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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000624-TA|BGIBMGA000624-PA|IPR001452|Src homology-3,
IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2,
IPR003961|Fibronectin, type III, IPR003962|Fibronectin, type III
subdomain, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin
I-set, IPR008957|Fibronectin, type III-like fold
         (2130 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|...  3397   0.0  
UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes a...  1868   0.0  
UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - ...  1773   0.0  
UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora...   830   0.0  
UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gamb...   793   0.0  
UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isof...   388   e-106
UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn...   344   2e-92
UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ...   318   8e-85
UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin -...   315   1e-83
UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin ...   312   9e-83
UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein;...   311   1e-82
UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Hom...   299   7e-79
UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whol...   287   3e-75
UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - ...   270   2e-70
UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whol...   268   1e-69
UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus...   266   3e-69
UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; ...   266   5e-69
UniRef50_UPI0000E460FC Cluster: PREDICTED: similar to Bent, part...   256   6e-66
UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole...   254   1e-65
UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep...   245   9e-63
UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whol...   244   2e-62
UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa...   235   1e-59
UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole...   231   2e-58
UniRef50_Q14324 Cluster: Myosin-binding protein C, fast-type; n=...   231   2e-58
UniRef50_UPI00015A6D36 Cluster: UPI00015A6D36 related cluster; n...   228   1e-57
UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh...   227   2e-57
UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella ve...   224   2e-56
UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whol...   222   7e-56
UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB...   219   9e-55
UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n...   215   1e-53
UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP000...   214   3e-53
UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Re...   213   4e-53
UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ...   212   8e-53
UniRef50_UPI0000F1EF40 Cluster: PREDICTED: similar to novel immu...   198   2e-48
UniRef50_Q7YRF6 Cluster: Cardiac titin; n=4; Eutheria|Rep: Cardi...   193   4e-47
UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG3351...   193   4e-47
UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome sh...   192   7e-47
UniRef50_Q1JPV5 Cluster: Zgc:136545; n=3; Danio rerio|Rep: Zgc:1...   192   9e-47
UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -...   192   1e-46
UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin ...   190   5e-46
UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein;...   186   4e-45
UniRef50_Q8N9C0 Cluster: Immunoglobulin superfamily member 22; n...   186   6e-45
UniRef50_UPI0000F33BB2 Cluster: Connectin; n=1; Bos taurus|Rep: ...   185   1e-44
UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscuri...   184   3e-44
UniRef50_A5PF15 Cluster: Novel protein similar to human obscurin...   182   7e-44
UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome sh...   182   1e-43
UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole...   180   4e-43
UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA...   178   1e-42
UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA...   176   6e-42
UniRef50_UPI0000ECA094 Cluster: eEF1A2 binding protein; n=3; Gal...   174   2e-41
UniRef50_Q8T104 Cluster: Projectin-like protein; n=1; Bombyx mor...   174   2e-41
UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB...   173   3e-41
UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel immu...   172   8e-41
UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA...   172   8e-41
UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=...   172   1e-40
UniRef50_Q7ZWM9 Cluster: LOC398550 protein; n=2; Xenopus|Rep: LO...   170   3e-40
UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - ...   170   3e-40
UniRef50_UPI00015A4170 Cluster: eEF1A2 binding protein; n=1; Dan...   170   4e-40
UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel he...   169   1e-39
UniRef50_Q4SK55 Cluster: Chromosome 2 SCAF14570, whole genome sh...   169   1e-39
UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG3...   168   2e-39
UniRef50_Q4RE91 Cluster: Chromosome undetermined SCAF15134, whol...   167   3e-39
UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-P...   164   3e-38
UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;...   162   8e-38
UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome s...   162   8e-38
UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB...   162   1e-37
UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and ...   159   6e-37
UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35...   159   1e-36
UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000...   158   1e-36
UniRef50_Q86VF2 Cluster: EEF1A2 binding protein; n=9; Euteleosto...   157   2e-36
UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gamb...   157   3e-36
UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella ve...   155   1e-35
UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|...   153   4e-35
UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s...   152   1e-34
UniRef50_Q676A1 Cluster: Cardiac myosin-binding protein C; n=1; ...   151   2e-34
UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus C...   150   4e-34
UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: H...   150   4e-34
UniRef50_Q4SM88 Cluster: Chromosome 3 SCAF14553, whole genome sh...   149   6e-34
UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n...   148   1e-33
UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella ve...   148   1e-33
UniRef50_UPI00005A1317 Cluster: PREDICTED: similar to eEF1A2 bin...   146   4e-33
UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopall...   146   4e-33
UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: C...   145   1e-32
UniRef50_P54296 Cluster: Myomesin-2; n=33; Euteleostomi|Rep: Myo...   144   3e-32
UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopteryg...   142   9e-32
UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin...   142   1e-31
UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella ve...   141   2e-31
UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome s...   140   4e-31
UniRef50_UPI0000F2E010 Cluster: PREDICTED: similar to chondroiti...   139   7e-31
UniRef50_P52179 Cluster: Myomesin-1; n=19; Euteleostomi|Rep: Myo...   139   7e-31
UniRef50_Q14896 Cluster: Myosin-binding protein C, cardiac-type;...   139   9e-31
UniRef50_UPI000065FB77 Cluster: Myomesin-1 (190 kDa titin-associ...   138   1e-30
UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscl...   138   2e-30
UniRef50_Q4RH24 Cluster: Chromosome 18 SCAF15072, whole genome s...   136   5e-30
UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscl...   136   5e-30
UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella ve...   136   8e-30
UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome ...   135   1e-29
UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscl...   135   1e-29
UniRef50_UPI0000F201CC Cluster: PREDICTED: similar to Myomesin 2...   135   1e-29
UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndr...   135   1e-29
UniRef50_A7DN46 Cluster: Fibronectin, type III domain protein pr...   134   3e-29
UniRef50_Q4STB1 Cluster: Chromosome 11 SCAF14249, whole genome s...   134   3e-29
UniRef50_UPI0000660A1C Cluster: Homolog of Gallus gallus "Myosin...   132   8e-29
UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-li...   130   4e-28
UniRef50_UPI0000E8095E Cluster: PREDICTED: similar to novel immu...   129   7e-28
UniRef50_UPI0000ECB822 Cluster: Obscurin-like protein 1 precurso...   128   2e-27
UniRef50_Q4RH47 Cluster: Chromosome undetermined SCAF15069, whol...   128   2e-27
UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladi...   127   3e-27
UniRef50_UPI000065E224 Cluster: eEF1A2 binding protein; n=2; Tak...   127   4e-27
UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar...   127   4e-27
UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep: P...   127   4e-27
UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion mole...   126   9e-27
UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella ve...   126   9e-27
UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleosto...   126   9e-27
UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p...   125   1e-26
UniRef50_UPI000066030F Cluster: Myomesin-2 (M-protein) (165 kDa ...   124   3e-26
UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome sh...   123   5e-26
UniRef50_UPI0000F1EA79 Cluster: PREDICTED: hypothetical protein;...   123   6e-26
UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin -...   122   1e-25
UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|...   122   1e-25
UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n...   121   3e-25
UniRef50_Q17AE8 Cluster: Titin; n=3; Culicidae|Rep: Titin - Aede...   120   3e-25
UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 pr...   120   4e-25
UniRef50_A0RX14 Cluster: Putative uncharacterized protein; n=1; ...   118   1e-24
UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome sh...   118   2e-24
UniRef50_Q53EP0 Cluster: Fibronectin type III domain-containing ...   117   3e-24
UniRef50_A7RGL5 Cluster: Predicted protein; n=1; Nematostella ve...   117   4e-24
UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella ve...   116   5e-24
UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep...   115   1e-23
UniRef50_Q9Y2H6 Cluster: Fibronectin type-III domain-containing ...   115   1e-23
UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemi...   115   2e-23
UniRef50_UPI0000E46511 Cluster: PREDICTED: similar to Fibronecti...   114   2e-23
UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precur...   114   2e-23
UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein;...   113   4e-23
UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, memb...   113   4e-23
UniRef50_P98160 Cluster: Basement membrane-specific heparan sulf...   113   5e-23
UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein;...   113   7e-23
UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein;...   112   9e-23
UniRef50_UPI0000D5788D Cluster: PREDICTED: similar to CG31738-PB...   112   9e-23
UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd prot...   112   1e-22
UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger ...   112   1e-22
UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep: Conn...   112   1e-22
UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|R...   112   1e-22
UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone speci...   111   2e-22
UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,...   111   2e-22
UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphat...   111   3e-22
UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n...   110   4e-22
UniRef50_Q172S1 Cluster: Stretchin-mlck; n=1; Aedes aegypti|Rep:...   110   4e-22
UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin...   110   5e-22
UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella ve...   110   5e-22
UniRef50_Q62234 Cluster: Myomesin-1; n=32; cellular organisms|Re...   109   6e-22
UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gal...   109   8e-22
UniRef50_Q4STB0 Cluster: Chromosome 11 SCAF14249, whole genome s...   109   8e-22
UniRef50_A6H8Q3 Cluster: Zgc:165344 protein; n=9; Clupeocephala|...   108   1e-21
UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA...   107   3e-21
UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphat...   107   3e-21
UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleosto...   107   3e-21
UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|...   107   4e-21
UniRef50_Q4RFP3 Cluster: Chromosome 16 SCAF15113, whole genome s...   106   6e-21
UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Eut...   106   6e-21
UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|...   106   8e-21
UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=2...   105   1e-20
UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2...   105   2e-20
UniRef50_UPI0000DB7210 Cluster: PREDICTED: similar to Stretchin-...   104   2e-20
UniRef50_Q4S0Y7 Cluster: Chromosome 5 SCAF14773, whole genome sh...   104   3e-20
UniRef50_A6NI63 Cluster: Uncharacterized protein MYOM3; n=42; Te...   104   3e-20
UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundab...   103   4e-20
UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC...   103   4e-20
UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;...   103   5e-20
UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA ...   103   5e-20
UniRef50_Q15772 Cluster: Striated muscle preferentially expresse...   103   5e-20
UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|...   103   5e-20
UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout...   103   7e-20
UniRef50_Q4SK53 Cluster: Chromosome 2 SCAF14570, whole genome sh...   103   7e-20
UniRef50_A7RZM7 Cluster: Predicted protein; n=1; Nematostella ve...   103   7e-20
UniRef50_Q4S5Q4 Cluster: Chromosome 9 SCAF14729, whole genome sh...   102   1e-19
UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell ad...   101   2e-19
UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome s...   101   2e-19
UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome s...   101   3e-19
UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA...   100   4e-19
UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-...   100   5e-19
UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG3...   100   5e-19
UniRef50_Q696W0 Cluster: Striated muscle preferentially expresse...   100   5e-19
UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t...    99   7e-19
UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -...   100   9e-19
UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleosto...   100   9e-19
UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor ...    99   1e-18
UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precur...    99   1e-18
UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan su...    98   2e-18
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ...    98   2e-18
UniRef50_A1L1W0 Cluster: Zgc:158442; n=3; Danio rerio|Rep: Zgc:1...    98   2e-18
UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanog...    98   2e-18
UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precurs...    98   3e-18
UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kD...    98   3e-18
UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote...    97   4e-18
UniRef50_Q177W1 Cluster: Factor for adipocyte differentiation; n...    97   4e-18
UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Eut...    97   4e-18
UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin p...    97   5e-18
UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; E...    97   5e-18
UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whol...    97   6e-18
UniRef50_Q1CVL1 Cluster: FG-GAP repeat/fibronectin type III doma...    97   6e-18
UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whol...    96   8e-18
UniRef50_Q9N3X8 Cluster: Protein sidekick homolog precursor; n=2...    96   8e-18
UniRef50_Q13203 Cluster: Myosin-binding protein H; n=35; Tetrapo...    96   8e-18
UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p...    96   8e-18
UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Da...    96   1e-17
UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9...    96   1e-17
UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eum...    95   1e-17
UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB...    95   2e-17
UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttn...    95   2e-17
UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome s...    95   2e-17
UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio reri...    95   2e-17
UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygo...    95   2e-17
UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: ...    95   2e-17
UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 ...    95   2e-17
UniRef50_UPI000155E24A Cluster: PREDICTED: similar to myosin bin...    94   3e-17
UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin lig...    94   3e-17
UniRef50_A4AI84 Cluster: Serine protease, subtilase family prote...    94   3e-17
UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin...    94   4e-17
UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc...    94   4e-17
UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; E...    94   4e-17
UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precurs...    94   4e-17
UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome s...    93   6e-17
UniRef50_A7RYG4 Cluster: Predicted protein; n=1; Nematostella ve...    93   6e-17
UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM pro...    93   1e-16
UniRef50_UPI0000DA2C8C Cluster: PREDICTED: similar to myosin bin...    93   1e-16
UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whol...    92   1e-16
UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome sh...    92   1e-16
UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ ...    92   1e-16
UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle pro...    91   2e-16
UniRef50_UPI0000D9D1DB Cluster: PREDICTED: similar to obscurin, ...    91   2e-16
UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome sh...    91   3e-16
UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome s...    91   3e-16
UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precurs...    91   3e-16
UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella ve...    91   4e-16
UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled p...    90   5e-16
UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Ne...    90   5e-16
UniRef50_Q05D81 Cluster: MYLK protein; n=14; Eutheria|Rep: MYLK ...    90   5e-16
UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; C...    90   5e-16
UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whol...    90   7e-16
UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome sh...    90   7e-16
UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin...    89   9e-16
UniRef50_UPI00015A6655 Cluster: myomesin family, member 3; n=6; ...    89   9e-16
UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella ve...    89   9e-16
UniRef50_UPI0000F2C7E8 Cluster: PREDICTED: similar to myomesin 1...    89   1e-15
UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin ...    89   1e-15
UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic a...    89   1e-15
UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whol...    89   1e-15
UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin...    89   2e-15
UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebr...    88   2e-15
UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whol...    88   2e-15
UniRef50_A7RGL3 Cluster: Predicted protein; n=1; Nematostella ve...    88   2e-15
UniRef50_A6NGQ3 Cluster: Uncharacterized protein OBSCN; n=2; Hom...    88   2e-15
UniRef50_O97394 Cluster: Protein sidekick precursor; n=9; Endopt...    88   2e-15
UniRef50_Q9VN14 Cluster: Contactin precursor; n=4; Endopterygota...    88   2e-15
UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA...    88   3e-15
UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembr...    88   3e-15
UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome sh...    88   3e-15
UniRef50_Q8T102 Cluster: Titin-like protein; n=3; Bombyx mori|Re...    88   3e-15
UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like p...    87   4e-15
UniRef50_UPI0000F20573 Cluster: PREDICTED: similar to hCG1644439...    87   5e-15
UniRef50_UPI0000D8D180 Cluster: UPI0000D8D180 related cluster; n...    87   5e-15
UniRef50_UPI00015B6345 Cluster: PREDICTED: similar to CG33141-PB...    87   7e-15
UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-ri...    87   7e-15
UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole...    87   7e-15
UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome sh...    87   7e-15
UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep: Round...    87   7e-15
UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin - ...    87   7e-15
UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep:...    87   7e-15
UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Re...    87   7e-15
UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep: Rou...    86   9e-15
UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella ve...    86   9e-15
UniRef50_UPI0000DB7559 Cluster: PREDICTED: similar to sticks and...    86   1e-14
UniRef50_UPI000065E234 Cluster: Homolog of Homo sapiens "OTTHUMP...    86   1e-14
UniRef50_Q7ZY97 Cluster: Tn3 protein; n=2; Xenopus|Rep: Tn3 prot...    86   1e-14
UniRef50_P32004 Cluster: Neural cell adhesion molecule L1 precur...    86   1e-14
UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout...    85   2e-14
UniRef50_Q3MHW8 Cluster: PALLD protein; n=7; Euteleostomi|Rep: P...    85   2e-14
UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1; ...    85   2e-14
UniRef50_UPI0000DB6D94 Cluster: PREDICTED: similar to CG33274-PA...    85   2e-14
UniRef50_UPI0000D55947 Cluster: PREDICTED: similar to CG33141-PA...    85   2e-14
UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527...    85   3e-14
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ...    85   3e-14
UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-ri...    85   3e-14
UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA...    85   3e-14
UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA;...    85   3e-14
UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecul...    85   3e-14
UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n...    84   4e-14
UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet; n...    84   4e-14
UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n...    84   5e-14
UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB...    84   5e-14
UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep: Rou...    84   5e-14
UniRef50_A7DN09 Cluster: Fibronectin, type III domain protein pr...    84   5e-14
UniRef50_UPI0000EB3119 Cluster: UPI0000EB3119 related cluster; n...    83   6e-14
UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhes...    83   8e-14
UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep...    83   8e-14
UniRef50_Q17AE6 Cluster: Kinesin motor protein, putative; n=2; C...    83   8e-14
UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens "OTTHUMP...    83   1e-13
UniRef50_Q7PRK4 Cluster: ENSANGP00000000600; n=1; Anopheles gamb...    83   1e-13
UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1; Du...    83   1e-13
UniRef50_A7T084 Cluster: Predicted protein; n=1; Nematostella ve...    83   1e-13
UniRef50_Q8N237 Cluster: CDNA FLJ34965 fis, clone NTONG2004308; ...    83   1e-13
UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome s...    82   1e-13
UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome sh...    82   1e-13
UniRef50_Q4RKT9 Cluster: Chromosome 1 SCAF15025, whole genome sh...    82   1e-13
UniRef50_Q9VJJ9 Cluster: CG31738-PB, isoform B; n=3; Drosophila ...    82   1e-13
UniRef50_UPI00005A24A2 Cluster: PREDICTED: similar to Glyceralde...    82   2e-13
UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n...    82   2e-13
UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella ve...    82   2e-13
UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31; Euteleosto...    82   2e-13
UniRef50_UPI0000F1E7B2 Cluster: PREDICTED: hypothetical protein;...    81   2e-13
UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome s...    81   2e-13
UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32; Euteleostomi|...    81   2e-13
UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38; Euteleosto...    81   2e-13
UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmoduli...    81   3e-13
UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36...    81   3e-13
UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|...    81   3e-13
UniRef50_A7SVH5 Cluster: Predicted protein; n=1; Nematostella ve...    81   3e-13
UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ...    81   4e-13
UniRef50_UPI0000E48846 Cluster: PREDICTED: similar to CG1915-PC;...    81   4e-13
UniRef50_UPI00006A08CF Cluster: myomesin family, member 3; n=1; ...    81   4e-13
UniRef50_Q8MQ86 Cluster: Putative uncharacterized protein F02G3....    81   4e-13
UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD...    80   6e-13
UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ...    80   6e-13
UniRef50_Q4SF99 Cluster: Chromosome undetermined SCAF14606, whol...    80   6e-13
UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome s...    80   6e-13
UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodopt...    80   6e-13
UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome sh...    80   8e-13
UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome s...    80   8e-13
UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and immunoglobulin...    80   8e-13
UniRef50_Q96JA1 Cluster: Leucine-rich repeats and immunoglobulin...    80   8e-13
UniRef50_Q4RE93 Cluster: Chromosome undetermined SCAF15134, whol...    79   1e-12
UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella ve...    79   1e-12
UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep:...    79   1e-12
UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel immu...    79   1e-12
UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase) hom...    79   1e-12
UniRef50_Q7PQF4 Cluster: ENSANGP00000011303; n=1; Anopheles gamb...    79   2e-12
UniRef50_A7SQD9 Cluster: Predicted protein; n=2; Nematostella ve...    79   2e-12
UniRef50_A7DN16 Cluster: Fibronectin, type III domain protein; n...    79   2e-12
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso...    79   2e-12
UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep: B...    78   2e-12
UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome sh...    78   2e-12
UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ...    78   3e-12
UniRef50_Q5W433 Cluster: Sialic-acid binding protein-4 precursor...    78   3e-12
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole...    77   4e-12
UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2...    77   4e-12
UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin, ...    77   5e-12
UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasi...    77   5e-12
UniRef50_Q4STY2 Cluster: Chromosome 10 SCAF14066, whole genome s...    77   5e-12
UniRef50_UPI0000EBE875 Cluster: PREDICTED: similar to Gene model...    77   7e-12
UniRef50_UPI000069F41E Cluster: Myosin light chain kinase, smoot...    77   7e-12
UniRef50_Q7Z553 Cluster: MAM domain-containing glycosylphosphati...    77   7e-12
UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB...    76   9e-12
UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-ri...    76   9e-12
UniRef50_Q4RRD1 Cluster: Chromosome 16 SCAF15002, whole genome s...    76   9e-12
UniRef50_Q6DFV6 Cluster: Gene model 784,; n=13; Murinae|Rep: Gen...    76   9e-12
UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome sh...    76   1e-11
UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome sh...    76   1e-11
UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Re...    76   1e-11
UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23; T...    76   1e-11
UniRef50_Q4KMG0 Cluster: Cell adhesion molecule-related/down-reg...    76   1e-11
UniRef50_UPI00015A663C Cluster: myomesin family, member 3; n=4; ...    75   2e-11
UniRef50_UPI00006A231D Cluster: Brother of CDO precursor (Protei...    75   2e-11
UniRef50_Q4T1T8 Cluster: Chromosome 2 SCAF10486, whole genome sh...    75   2e-11
UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece...    75   2e-11
UniRef50_Q17G58 Cluster: Lachesin; n=3; Culicidae|Rep: Lachesin ...    75   2e-11
UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella ve...    75   2e-11
UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep: P...    75   3e-11
UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hir...    75   3e-11
UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB...    74   4e-11
UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio ...    74   4e-11
UniRef50_UPI000069DD8B Cluster: Leucine-rich repeats and immunog...    74   4e-11
UniRef50_Q308M3 Cluster: Protein tyrosine phosphatase receptor t...    74   4e-11
UniRef50_Q18066 Cluster: Disorganized muscle protein 1; n=4; Chr...    74   4e-11
UniRef50_P05548 Cluster: CAVP-target protein; n=1; Branchiostoma...    74   4e-11
UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio r...    74   5e-11
UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome sh...    74   5e-11
UniRef50_A7RT95 Cluster: Predicted protein; n=1; Nematostella ve...    74   5e-11
UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella ve...    74   5e-11
UniRef50_O94898 Cluster: Leucine-rich repeats and immunoglobulin...    74   5e-11
UniRef50_Q4S969 Cluster: Chromosome 3 SCAF14700, whole genome sh...    73   7e-11
UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome s...    73   7e-11
UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ...    73   7e-11
UniRef50_UPI0000DB6DA8 Cluster: PREDICTED: similar to CG32387-PB...    73   9e-11
UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasi...    73   9e-11
UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep...    73   9e-11
UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome sh...    73   9e-11
UniRef50_A4X2B3 Cluster: Fibronectin, type III domain protein; n...    73   9e-11
UniRef50_A0JUG0 Cluster: Fibronectin, type III domain protein pr...    73   9e-11
UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27; Euteleo...    73   9e-11
UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular...    73   1e-10
UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n...    73   1e-10
UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome s...    73   1e-10
UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome sh...    73   1e-10
UniRef50_Q2EGT7 Cluster: Limbic system-associated membrane prote...    73   1e-10
UniRef50_P22648 Cluster: Fasciclin-2 precursor; n=1; Schistocerc...    73   1e-10
UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine kin...    72   2e-10
UniRef50_Q592R0 Cluster: Putative uncharacterized protein; n=1; ...    72   2e-10
UniRef50_Q0E9F2 Cluster: CG33141-PB, isoform B; n=9; Diptera|Rep...    72   2e-10
UniRef50_Q13449 Cluster: Limbic system-associated membrane prote...    72   2e-10
UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA;...    72   2e-10
UniRef50_Q9VCT4 Cluster: CG6669-PA; n=8; Diptera|Rep: CG6669-PA ...    72   2e-10
UniRef50_Q7PRJ5 Cluster: ENSANGP00000024207; n=3; Endopterygota|...    72   2e-10
UniRef50_A7RTW2 Cluster: Predicted protein; n=1; Nematostella ve...    72   2e-10
UniRef50_A7RGL6 Cluster: Predicted protein; n=1; Nematostella ve...    72   2e-10
UniRef50_Q26475 Cluster: REGA-1 protein precursor; n=1; Schistoc...    71   3e-10
UniRef50_O97137 Cluster: Fasciclin II transmembrane isoform; n=3...    71   3e-10
UniRef50_A7SS32 Cluster: Predicted protein; n=6; Nematostella ve...    71   3e-10
UniRef50_Q18245 Cluster: Ig-like and fibronectin type-III domain...    71   3e-10
UniRef50_Q7TPW1 Cluster: Nexilin; n=12; Euteleostomi|Rep: Nexili...    71   3e-10
UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep...    71   3e-10
UniRef50_UPI0000E4754C Cluster: PREDICTED: similar to DDM36; n=1...    71   4e-10
UniRef50_Q0ZGT2 Cluster: Nexilin; n=25; Euteleostomi|Rep: Nexili...    71   4e-10
UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583; ...    71   5e-10
UniRef50_UPI0000EB292A Cluster: Leucine-rich repeats and immunog...    71   5e-10
UniRef50_O18466 Cluster: LeechCAM; n=1; Hirudo medicinalis|Rep: ...    71   5e-10
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot...    71   5e-10
UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopu...    70   6e-10
UniRef50_Q4RQR3 Cluster: Chromosome 2 SCAF15004, whole genome sh...    70   6e-10
UniRef50_Q16UD9 Cluster: Sidestep protein; n=1; Aedes aegypti|Re...    70   6e-10
UniRef50_A7T5G7 Cluster: Predicted protein; n=1; Nematostella ve...    70   6e-10
UniRef50_A2A344 Cluster: ADAMTS-like 1; n=29; Euteleostomi|Rep: ...    70   6e-10
UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule p...    70   6e-10
UniRef50_UPI0000F1E5DD Cluster: PREDICTED: hypothetical protein;...    70   8e-10
UniRef50_UPI0000F1DA2E Cluster: PREDICTED: hypothetical protein;...    70   8e-10
UniRef50_Q7QJK6 Cluster: ENSANGP00000010870; n=1; Anopheles gamb...    70   8e-10
UniRef50_Q7QCP2 Cluster: ENSANGP00000010242; n=1; Anopheles gamb...    70   8e-10
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece...    70   8e-10
UniRef50_UPI0000DB6DA7 Cluster: PREDICTED: similar to Protein ty...    69   1e-09
UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob...    69   1e-09
UniRef50_UPI0000E80F57 Cluster: PREDICTED: hypothetical protein;...    69   1e-09
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu...    69   1e-09
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot...    69   1e-09
UniRef50_UPI0000F1DED3 Cluster: PREDICTED: similar to sialic-aci...    69   1e-09
UniRef50_UPI0000D9DD6E Cluster: PREDICTED: similar to hemicentin...    69   1e-09
UniRef50_A2BEV6 Cluster: Novel protein; n=8; Danio rerio|Rep: No...    69   1e-09
UniRef50_UPI00015B5C2D Cluster: PREDICTED: similar to lachesin; ...    69   2e-09
UniRef50_UPI0000E49A7A Cluster: PREDICTED: hypothetical protein,...    69   2e-09
UniRef50_A7RYG0 Cluster: Predicted protein; n=1; Nematostella ve...    69   2e-09
UniRef50_P15364 Cluster: Protein amalgam precursor; n=6; melanog...    69   2e-09
UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian...    68   2e-09
UniRef50_Q4RU88 Cluster: Chromosome 1 SCAF14995, whole genome sh...    68   2e-09
UniRef50_Q9V787 Cluster: Hibris; n=4; Sophophora|Rep: Hibris - D...    68   3e-09
UniRef50_Q5WRR1 Cluster: Wrapper/rega-1/klingon homolog protein ...    68   3e-09
UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor (...    67   4e-09
UniRef50_Q4ACB4 Cluster: Mahya; n=3; Endopterygota|Rep: Mahya - ...    67   4e-09
UniRef50_UPI00015B48D7 Cluster: PREDICTED: similar to lachesin; ...    66   8e-09
UniRef50_UPI0000DBF155 Cluster: UPI0000DBF155 related cluster; n...    66   8e-09
UniRef50_Q9VMN6 Cluster: CG31646-PA; n=9; Endopterygota|Rep: CG3...    66   8e-09
UniRef50_Q3SA91 Cluster: Putative uncharacterized protein; n=1; ...    66   8e-09
UniRef50_Q97Z97 Cluster: Kelch domain-containing protein SSO1033...    66   8e-09
UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhes...    66   1e-08
UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein;...    66   1e-08
UniRef50_UPI0000D8BAD9 Cluster: UPI0000D8BAD9 related cluster; n...    66   1e-08
UniRef50_Q4RFN0 Cluster: Chromosome 16 SCAF15113, whole genome s...    66   1e-08
UniRef50_Q9BN17 Cluster: Echinoid; n=10; Diptera|Rep: Echinoid -...    66   1e-08
UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella ve...    66   1e-08
UniRef50_UPI0000F21178 Cluster: PREDICTED: hypothetical protein;...    66   1e-08
UniRef50_Q4TAJ7 Cluster: Chromosome undetermined SCAF7304, whole...    66   1e-08
UniRef50_UPI0000F1D4AE Cluster: PREDICTED: similar to sidekick 1...    65   2e-08
UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein ty...    65   2e-08
UniRef50_UPI000069F509 Cluster: Uncharacterized protein C9orf94 ...    65   2e-08
UniRef50_UPI000069DA70 Cluster: Protein tyrosine phosphatase RQ;...    65   2e-08
UniRef50_Q4SYB6 Cluster: Chromosome 11 SCAF12108, whole genome s...    65   2e-08
UniRef50_Q4RKU0 Cluster: Chromosome 1 SCAF15025, whole genome sh...    65   2e-08
UniRef50_Q59E14 Cluster: CG33543-PC; n=3; Sophophora|Rep: CG3354...    65   2e-08
UniRef50_UPI0000F20868 Cluster: PREDICTED: similar to sialic-aci...    65   2e-08
UniRef50_UPI0000D55B25 Cluster: PREDICTED: similar to CG6669-PA;...    65   2e-08
UniRef50_UPI0000ECA5E8 Cluster: Transmembrane and immunoglobulin...    65   2e-08
UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R...    65   2e-08
UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella ve...    65   2e-08
UniRef50_O75445 Cluster: Usherin precursor; n=34; Eukaryota|Rep:...    65   2e-08
UniRef50_UPI0000E25314 Cluster: PREDICTED: similar to fast MyBP-...    64   3e-08
UniRef50_Q4STG8 Cluster: Chromosome undetermined SCAF14228, whol...    64   3e-08
UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gamb...    64   3e-08
UniRef50_Q22040 Cluster: Putative uncharacterized protein SSSD1....    64   3e-08
UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein;...    64   4e-08
UniRef50_UPI0000E48EAE Cluster: PREDICTED: similar to neuronal m...    64   4e-08
UniRef50_Q4TAD3 Cluster: Chromosome undetermined SCAF7373, whole...    64   4e-08
UniRef50_Q2WF53 Cluster: Neurotrimin; n=9; Clupeocephala|Rep: Ne...    64   4e-08
UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=2...    64   4e-08
UniRef50_Q7Z3B1 Cluster: Neuronal growth regulator 1 precursor; ...    64   4e-08
UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp...    64   5e-08
UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=2...    64   5e-08
UniRef50_UPI0000E4A429 Cluster: PREDICTED: similar to guanine de...    63   7e-08
UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio "Ro...    63   7e-08
UniRef50_Q4SUX1 Cluster: Chromosome undetermined SCAF13836, whol...    63   7e-08
UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome sh...    63   7e-08
UniRef50_A4JYK0 Cluster: Si:dkey-24p1.1; n=3; Danio rerio|Rep: S...    63   7e-08
UniRef50_Q09165 Cluster: Mesocentin precursor; n=5; Bilateria|Re...    63   7e-08
UniRef50_UPI0000E470DC Cluster: PREDICTED: hypothetical protein,...    63   9e-08
UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome sh...    63   9e-08
UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella ve...    63   9e-08
UniRef50_UPI00005889C1 Cluster: PREDICTED: similar to neural adh...    62   1e-07
UniRef50_UPI00004D96E1 Cluster: adlican; n=1; Xenopus tropicalis...    62   1e-07
UniRef50_Q9TWA6 Cluster: APCAM=CELL adhesion molecule from CDNA ...    62   1e-07
UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protei...    62   1e-07
UniRef50_Q059D2 Cluster: IP03328p; n=3; Endopterygota|Rep: IP033...    62   1e-07
UniRef50_A7T347 Cluster: Predicted protein; n=7; Nematostella ve...    62   1e-07
UniRef50_Q21043 Cluster: Putative uncharacterized protein pxn-2;...    62   2e-07

>UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|Rep:
            Titin-like protein - Bombyx mori (Silk moth)
          Length = 3354

 Score = 3397 bits (8431), Expect = 0.0
 Identities = 1634/1731 (94%), Positives = 1637/1731 (94%), Gaps = 28/1731 (1%)

Query: 413  TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ 472
            TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ
Sbjct: 1639 TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ 1698

Query: 473  YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
            YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ
Sbjct: 1699 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 1758

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
            VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA
Sbjct: 1759 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 1818

Query: 593  SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652
            SSTTELIVEAPLSDHGSEMTV            ADILEGIPPTFSKKPKAQYVDEGSDIL
Sbjct: 1819 SSTTELIVEAPLSDHGSEMTVLSRKSLSRESSLADILEGIPPTFSKKPKAQYVDEGSDIL 1878

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA
Sbjct: 1879 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 1938

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN
Sbjct: 1939 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 1998

Query: 773  KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
            KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP
Sbjct: 1999 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 2058

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            PLFINRFQEITVKEKGTIKLVARVT NPVPSITWYRNNEIISPSETITQNFDGENIELVI
Sbjct: 2059 PLFINRFQEITVKEKGTIKLVARVTGNPVPSITWYRNNEIISPSETITQNFDGENIELVI 2118

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
            TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT
Sbjct: 2119 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 2178

Query: 953  SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012
            SHTVSTKWYHNKKEISGMDHREIIQEGR            DVGVIKCIVKDQETSTMLVV
Sbjct: 2179 SHTVSTKWYHNKKEISGMDHREIIQEGRIHKLKIKKTKLTDVGVIKCIVKDQETSTMLVV 2238

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR
Sbjct: 2239 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 2298

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132
            KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK
Sbjct: 2299 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 2358

Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE
Sbjct: 2359 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 2418

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT
Sbjct: 2419 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 2478

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
            LIIRKCTEDDQCEYTCVLLDAKS+TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ
Sbjct: 2479 LIIRKCTEDDQCEYTCVLLDAKSSTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 2538

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
            AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE
Sbjct: 2539 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 2598

Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
            MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN
Sbjct: 2599 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 2658

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
            ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT
Sbjct: 2659 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 2718

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
            TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR               YKCIA
Sbjct: 2719 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRVATLVVTVTETTIGTYKCIA 2778

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK
Sbjct: 2779 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 2838

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP
Sbjct: 2839 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 2898

Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732
            VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN
Sbjct: 2899 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 2958

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
            ENCEYMFRVIAQNPVGFSEALESEPIVIKTAL +            IDNESVYITWFPSE
Sbjct: 2959 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALGL----------YGIDNESVYITWFPSE 3008

Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
            KNGGSPIIDYKVEIKQEGKKWK         ARIQKLSINTTYQFRIYARNEIGTSLPYT
Sbjct: 3009 KNGGSPIIDYKVEIKQEGKKWKTITTVTETTARIQKLSINTTYQFRIYARNEIGTSLPYT 3068

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
            SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW
Sbjct: 3069 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 3128

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA--------- 1963
            TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA         
Sbjct: 3129 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAQAYTSQTYL 3188

Query: 1964 ----TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
                 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV
Sbjct: 3189 FFCSAVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 3248

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
            DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG+     PGEQTEV
Sbjct: 3249 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGT-----PGEQTEV 3303

Query: 2080 XXXXXXXXXXXXXWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 2130
                         WLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK
Sbjct: 3304 TEPTSFSTQTTTSWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 3354



 Score =  694 bits (1714), Expect = 0.0
 Identities = 349/407 (85%), Positives = 349/407 (85%)

Query: 1    MKPKSNEKEVLSDSSEDKIIPPEEQXXXXXXXXXXXXXXXXXILRKLQIEELESSKPQHP 60
            MKPKSNEKEVLSDSSEDKIIPPEEQ                 ILRKLQIEELESSKPQHP
Sbjct: 967  MKPKSNEKEVLSDSSEDKIIPPEEQKSEPKLLLNNKKSKDKPILRKLQIEELESSKPQHP 1026

Query: 61   EEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK 120
            EEMTVPQF             QEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK
Sbjct: 1027 EEMTVPQFSKLKLKKSSVLPKQEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK 1086

Query: 121  QNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE 180
            QNGELSRNVKEAN             DLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE
Sbjct: 1087 QNGELSRNVKEANKIKKKKLKLPKIPDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE 1146

Query: 181  AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM 240
            AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM
Sbjct: 1147 AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM 1206

Query: 241  EVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPL 300
            EVSTPQHAETVDGPQF              ETSLVKLPKFQLKSRIKYITSWPPESIKPL
Sbjct: 1207 EVSTPQHAETVDGPQFTLPKLKKTAVKPKKETSLVKLPKFQLKSRIKYITSWPPESIKPL 1266

Query: 301  ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360
            ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE
Sbjct: 1267 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 1326

Query: 361  IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNP 407
            IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL P
Sbjct: 1327 IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLKP 1373


>UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes
            aegypti|Rep: Myosin light chain kinase - Aedes aegypti
            (Yellowfever mosquito)
          Length = 4604

 Score = 1868 bits (4632), Expect = 0.0
 Identities = 917/1840 (49%), Positives = 1223/1840 (66%), Gaps = 43/1840 (2%)

Query: 315  RNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKE 374
            + + E  +V  +V       DVE+ E ++    YE+  +++    E+ + +Q LE L   
Sbjct: 2784 KEVNEDDEVVYEVIYDDSEVDVEEDEYDR----YEE-EDAEHVVLELRKRRQKLESLIVH 2838

Query: 375  DVPE-QYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAET 433
               E    +T RKS     +E     T+K++       Y+  E    + ++ +    AE 
Sbjct: 2839 QEEEISIDLTRRKSQVTHEEE---SFTLKQQKKSLAT-YSEEEA---NEMYCIQPVEAEN 2891

Query: 434  DEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKID 493
            +EAI+LVEGE++Y++D SN +WW+V++  +EE+G+   + LMD   Y QY+QK LNEKID
Sbjct: 2892 EEAIHLVEGEKVYVIDRSNPEWWFVKRSWSEERGFARRELLMDAVTYPQYVQKTLNEKID 2951

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            KLP+FEKP   E+  AP  +EKL+P  T DG TVQFEC+VEGYPRPQITWFRQTA+IKPS
Sbjct: 2952 KLPIFEKPAPSEKPQAPKIIEKLQPITTQDGYTVQFECKVEGYPRPQITWFRQTAVIKPS 3011

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            QDFQ+YYDDDNVATL+IREVFPEDAGTFTCVAKN AGFASSTTEL V++  SDHGSE+  
Sbjct: 3012 QDFQIYYDDDNVATLIIREVFPEDAGTFTCVAKNIAGFASSTTELSVDSFTSDHGSEVAT 3071

Query: 614  XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                        ADILEGIPPTFS+KPKAQYVD GSD+LLECRLVAIPEPDI W + G E
Sbjct: 3072 LSRKSMSRESSLADILEGIPPTFSRKPKAQYVDVGSDVLLECRLVAIPEPDIHWFYNGTE 3131

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
            I    NI V +ESDMHMYC+V++I N+ K QEG+Y VVA NREGE++L I +K+KTG  E
Sbjct: 3132 ITTKGNIDVVVESDMHMYCTVVQIRNIDKKQEGSYQVVARNREGESALDITVKVKTGVLE 3191

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
            PPQ++EPLKSM +RQGE+V+LS Q+VGNP P + W KN + +K  PT++D + +++T+L 
Sbjct: 3192 PPQILEPLKSMSIRQGETVMLSTQIVGNPTPEVQWFKNGEVLKT-PTQADKNMYTVTLLS 3250

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
            P   ++ G YT+KA+N+ G  ET+A +TV+E    N + PLF+ RF+E +V + GTIKL 
Sbjct: 3251 PTH-ENAGEYTVKAKNAAGTVETTAFLTVDESNVGNPQAPLFLERFEEQSVPQGGTIKLP 3309

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            A+V+ NPVP I W RNN  +  S+ + Q +DG+NIEL I+N DSE DSG+YKC+ASN+ G
Sbjct: 3310 AKVSGNPVPEILWLRNNNTLLTSKKVKQAYDGQNIELTISNADSEQDSGNYKCIASNTVG 3369

Query: 914  KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973
            K+SHGARVT++V++VTFVK L+K+   EE K+V LEC+TSHTVSTKW+HN KE+SGMDHR
Sbjct: 3370 KASHGARVTVEVDRVTFVKKLKKTVTVEESKSVTLECETSHTVSTKWFHNGKEMSGMDHR 3429

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
             I+QEG+            D G+ +C VKDQ T   L V E  PEFIRK++D E KEK  
Sbjct: 3430 VIVQEGKVHKLVIKNPTIKDTGMYQCTVKDQVTECSLTVLEAKPEFIRKMEDVETKEKQN 3489

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            A+LEVEI SETADVVW ++G+ I  +K KY+F K+G  R L +R+TSVHDEGEY+C L D
Sbjct: 3490 AVLEVEITSETADVVWYKEGKKIVEEKGKYEFSKKGKTRSLLVRSTSVHDEGEYTCALAD 3549

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
            + C+AEV V+ELPPEIIT L++  V +G  A F+IELTKGDALVRW++D +E+ F+ H Q
Sbjct: 3550 QECSAEVVVIELPPEIITPLKDVTVARGENAVFDIELTKGDALVRWYRDDTELSFNGHYQ 3609

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
            LTIDGK+Q LKI     +DAG Y C VG+   TA LTVE P ++F  RLP+  +    TD
Sbjct: 3610 LTIDGKRQTLKIIKTVDEDAGVYKCVVGDQLSTAKLTVERPLVDFVKRLPDVTIATKQTD 3669

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
            A   VE+  E+ +VTWYK    I+ + K+ LI+D K R LI++  TEDD+ EYTC + + 
Sbjct: 3670 AVFVVEL-SESAEVTWYKNSKKIKASSKYELIADKKVRKLIVKNVTEDDEDEYTCTIANV 3728

Query: 1274 KSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            K+++KLKVEV++  P I  D  R Y I++  DVT  V + A P+P+ EW VN K++    
Sbjct: 3729 KTSSKLKVEVIKVAPTIFDDGSRTYTIRKEDDVTFNVKFNATPKPDSEWYVNEKLVIPSP 3788

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
               P+I  ++ASLTIKKV  +DAG Y +RL N CG A     + +  +P  P  P   +I
Sbjct: 3789 RFVPTIGEETASLTIKKVVESDAGDYTVRLVNECGDASASFTLIVKRQPGAPDAPEATQI 3848

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
               SI + W  PE+ GNSTI  Y++EYQE    +W  + NI++T T++  L  NS Y FR
Sbjct: 3849 TDDSITLFWKSPEDNGNSTITEYILEYQEKSKKKWTEITNISETTTTVTKLTKNSEYTFR 3908

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              AVNE+    AS  + YYK+    K ++P V + LK++    ++ I LTCI  GVP P+
Sbjct: 3909 VTAVNEMGKGPASPNSPYYKIAAPIKKEAPVVSEHLKDVHIGLDQTITLTCIVNGVPTPE 3968

Query: 1513 VTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            V+WYR+G  LK    TYEN                 Y C A N+ G VE+SC V I++KP
Sbjct: 3969 VSWYRNGTALKEKTITYENGAAKYVIVKTTKETSGTYVCKAVNEVGSVESSCKVVIEEKP 4028

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             IT+  + I QK +VGDEW V A  EG P PE++WY+    +E+  E+ I T  K+S I 
Sbjct: 4029 TITVDKKQIVQKLRVGDEWTVVANFEGYPVPEIVWYREDEVIESTAEHTIVTISKSSTIV 4088

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            I +L RS S KY +EA N+AG++SVE+ LKV DKPSKPEGP+I++E+S E+V IEWKPP 
Sbjct: 4089 IGKLDRSDSGKYVVEARNSAGSASVELQLKVIDKPSKPEGPIIVKELSPEAVVIEWKPPA 4148

Query: 1692 DDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
            DDGGLE+++Y+IEK +  N N WIKVADV +++++YCIQKL ++ +Y FRVIAQNP+G S
Sbjct: 4149 DDGGLEISQYSIEKCDDTNKNAWIKVADVQKNIKSYCIQKLLDSTQYHFRVIAQNPIGCS 4208

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
            E LES  I +K  L+ PS          + + S  ++W PSE NGGS I +Y VE+K+  
Sbjct: 4209 EPLESATITVKQVLEPPSPPRGPIETSGMTSHSFTLSWQPSEHNGGSKITEYIVEMKESK 4268

Query: 1811 KK-WK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
            KK WK             I+ LS N  Y FRI+A+N+IGTS    +++ I  GK +TPPS
Sbjct: 4269 KKVWKVVGSTSASETSLLIENLSANRGYDFRIFAKNKIGTSEALQTEESIVAGKEITPPS 4328

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
             PRN  +   TS+S+ L+W +PE+NGGS +T Y+IE +    + WTKI T+  +   +C+
Sbjct: 4329 APRNLRIVNVTSKSIKLEWQQPETNGGSDVTGYVIEKRLTTSQQWTKIKTLDATCLSYCV 4388

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-----------------TVPSPPT 1970
            +N+KEK E++FR+ AEN +G+S P  S++V L+ +A                  VPSPPT
Sbjct: 4389 DNLKEKSELVFRVFAENVIGLSPPATSETVTLKSYAKISEKWLTIRIAFFFTTAVPSPPT 4448

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
             PLE+R +G NI +  WG PE DGGAPL GYNI IR++ KTMWMEVG+V  +   FNI+D
Sbjct: 4449 GPLEVRYLGPNINIVEWGIPESDGGAPLEGYNIVIRNIKKTMWMEVGRVSADCQSFNIKD 4508

Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXX 2090
            L+E+  Y+IRI ARNE+G S+PLES+EP+K   G    A E+  ++T             
Sbjct: 4509 LAEDEEYLIRIIARNEVGNSDPLESEEPYKAQLGA---APEDTHDET-TRDFTEPSATNT 4564

Query: 2091 XXWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 2130
              WLREHNM ADI SYAR  LLRR EYFF++W  AK LFK
Sbjct: 4565 SSWLREHNMTADIHSYARHKLLRRREYFFKLWVNAKNLFK 4604



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 71/248 (28%), Positives = 115/248 (46%), Gaps = 13/248 (5%)

Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
           D  E E + ++ + P+ I ++ K       E ++ + +   ++ E  + +   +  E   
Sbjct: 311 DHTEQEERTEIKKTPKKIKKKIKKSGP--SEEDEALERLLNLEVEKTQ-LEEYEKIELEA 367

Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPK 279
            P     + KL PI+IERKE + +  Q  ET D PQ               E   V +PK
Sbjct: 368 KPKLEKPKPKLEPIRIERKEQKATKLQITETEDQPQMIKLKKVKVPGKKEIEE--VVVPK 425

Query: 280 FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKT 339
             LKSR+  +  +PP    P IS + + K  G L+R  +E  K+K +     K    +K 
Sbjct: 426 VLLKSRMMMV-QYPPAVQYPQISTIVTKKGIGELARVNEEEEKIKLKKIKKIKTTKRDKL 484

Query: 340 ELEQ-PLFSYEDIV---ESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEI 395
           ELEQ  L  YE+ V   E K +E E  Q KQ  E++ +E  P+  T+   K   +K + +
Sbjct: 485 ELEQVDLPEYEEEVSEEEQKPEEKEKYQRKQK-EKVDEE--PQVKTLKLGKGIVKKDEPV 541

Query: 396 VDEVTIKK 403
            + +T+KK
Sbjct: 542 EETITLKK 549



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 55/180 (30%), Positives = 93/180 (51%), Gaps = 13/180 (7%)

Query: 229  KLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKY 288
            KL PIKIERKE +   P   E  D P+               E   V +PK  LKSR+  
Sbjct: 1588 KLEPIKIERKEQK---PTKLEITDTPEPQTVKLRKTVIPEKKEIEEVTVPKVLLKSRVVQ 1644

Query: 289  ITSWPPESIKPLISYMGSIKQNGILSR-----NIKEAAKVKKQVFVPPKLPDVEKTELEQ 343
            +  +PPE+ KP I  + + +  G LSR     + ++  K+KK   +  + P++E  ++E+
Sbjct: 1645 V-EYPPEAQKPKIVQLETKQGVGELSRIEEEEDERKVKKIKKVKVIKKEKPELEVLDIEK 1703

Query: 344  PLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKK 403
              F  E  V+ +K+E +   ++Q ++E P E+  E+ T+   K   +K ++ ++EV +KK
Sbjct: 1704 --FEKEPTVQEEKEEEKPKYQRQ-IKEKPVEET-EERTLVLGKGKLKKEEDEIEEVKLKK 1759



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 51/216 (23%), Positives = 84/216 (38%), Gaps = 11/216 (5%)

Query: 44   LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRD 103
            L  ++IE  E  KP   E    P+              +E   V +PK  LKSR+  + +
Sbjct: 1589 LEPIKIERKEQ-KPTKLEITDTPEPQTVKLRKTVIPEKKEIEEVTVPKVLLKSRVVQV-E 1646

Query: 104  WPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDL----- 158
            +PP+  KP +  L + +  GELSR  +E +               E+  LE  D+     
Sbjct: 1647 YPPEAQKPKIVQLETKQGVGELSRIEEEEDERKVKKIKKVKVIKKEKPELEVLDIEKFEK 1706

Query: 159  ---FDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV-PDD 214
                  +++E KP   +  +    E   E  L+    +   +  EI+    +K  V P +
Sbjct: 1707 EPTVQEEKEEEKPKYQRQIKEKPVEETEERTLVLGKGKLKKEEDEIEEVKLKKTPVRPKE 1766

Query: 215  KETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAET 250
            +E  +      K  K T  +I +K+  V  P    T
Sbjct: 1767 EEEVEAVIKKKKEEKPTEDEIIKKQKHVEKPTFTPT 1802



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 49/214 (22%), Positives = 91/214 (42%), Gaps = 12/214 (5%)

Query: 46  KLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRDWP 105
           +++ +E +++K Q  E    PQ               E  VV  PK  LKSR+  ++ +P
Sbjct: 382 RIERKEQKATKLQITETEDQPQMIKLKKVKVPGKKEIEEVVV--PKVLLKSRMMMVQ-YP 438

Query: 106 PQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQ--- 162
           P    P ++ + + K  GEL+R  +E                 +++ LE+ DL + +   
Sbjct: 439 PAVQYPQISTIVTKKGIGELARVNEEEEKIKLKKIKKIKTTKRDKLELEQVDLPEYEEEV 498

Query: 163 -EDESKPDVSQPPQ-NIIEEAKSEP--KLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218
            E+E KP+  +  Q    E+   EP  K ++  +  + K   ++  +  K      KE  
Sbjct: 499 SEEEQKPEEKEKYQRKQKEKVDEEPQVKTLKLGKGIVKKDEPVEETITLKKTPKKPKEDV 558

Query: 219 QTPTSFNKRSKLTP--IKIERKEMEVSTPQHAET 250
           +  T+  K+ K  P  I+ +++   V  P  + T
Sbjct: 559 EAETTSVKKPKQKPELIEHDKEHKHVQKPTFSPT 592



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 5/75 (6%)

Query: 335  DVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTIT--PRKSSAQKI 392
            +VEKTELEQ  +   D+   K+++ +I Q+ Q  ++  +  + E+ TI   PRK S +  
Sbjct: 2468 EVEKTELEQ--YEKVDVDFKKREKLKITQQPQP-QQAVESTIEEEQTIQLKPRKKSVKPS 2524

Query: 393  DEIVDEVTIKKRLNP 407
             E ++E  +  +L P
Sbjct: 2525 VETIEETEVAFKLKP 2539



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 49/207 (23%), Positives = 86/207 (41%), Gaps = 13/207 (6%)

Query: 203 NEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVST----PQHAETVDGPQFXX 258
           NE  EKI +   K+  +  T+   + +L  + +   E EVS     P+  E     Q   
Sbjct: 462 NEEEEKIKL---KKIKKIKTTKRDKLELEQVDLPEYEEEVSEEEQKPEEKEKYQRKQKEK 518

Query: 259 XXXXXXXXXXXXETSLVKLPK-FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNI 317
                          +VK  +  +    +K     P E ++   + +   KQ   L  + 
Sbjct: 519 VDEEPQVKTLKLGKGIVKKDEPVEETITLKKTPKKPKEDVEAETTSVKKPKQKPELIEHD 578

Query: 318 KEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKED-V 376
           KE   V+K  F P ++PDVE  ELE+       + +  ++E    +++    + PKED V
Sbjct: 579 KEHKHVQKPTFSPTEIPDVE-VELEE-YRQPSPVPDVPEEETPHKKKRSKKPKEPKEDEV 636

Query: 377 PEQYTITPRKSSAQKIDEIVDEVTIKK 403
           PE+  I  +    ++I E  ++V  +K
Sbjct: 637 PERPLIMGKGKKPEEIPE--EDVKFRK 661



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%)

Query: 335  DVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDE 394
            ++EKTELE+      +IV+  K   EI+ E++  EE   EDVPE+    P K   + I  
Sbjct: 2218 EIEKTELEKYEKVDIEIVKKPKTVEEIVVEQKP-EEPKVEDVPEEVVFKP-KPKDRVIKP 2275

Query: 395  IVDEVTIKKRL 405
            + +EV +  +L
Sbjct: 2276 VEEEVEVDFKL 2286


>UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin -
             Drosophila melanogaster (Fruit fly)
          Length = 18074

 Score = 1773 bits (4397), Expect = 0.0
 Identities = 859/1864 (46%), Positives = 1210/1864 (64%), Gaps = 57/1864 (3%)

Query: 301   ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360
             IS  G +K    + +   EAA   K + +     D E+  +E+ +   ED ++  ++  E
Sbjct: 16213 ISMSGKVKLKKPIKKTFSEAADEAK-IKIIQDFDDGEEPIIEE-IRDDEDTIDEVEEPEE 16270

Query: 361   IIQEKQTLEEL---------PK------EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL 405
                E+   +E+         PK      ++  EQ+ I  R      +    D +T KK+ 
Sbjct: 16271 YFVEELPPDEVDFKLKPKKHPKPAYSVQDEEEEQFLIGIRHPKRDSVTYDEDSLTFKKKR 16330

Query: 406   NPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEE 465
                +  +   E    + ++++ +Y+A+ +EAINLVEGE++ ++   + +WWYV+K  TEE
Sbjct: 16331 KVVQQLFNE-ESENLNIMYSICNYIADNNEAINLVEGEKVTVVGRHSSEWWYVKKSTTEE 16389

Query: 466   KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS 525
             +GWVPAQYLM+   Y QY+Q KL+EKIDKLPVFE+P  E++ +AP F+EKL+P HTPDG 
Sbjct: 16390 EGWVPAQYLMEPEEYAQYVQNKLHEKIDKLPVFERPGPEDKPIAPRFIEKLQPIHTPDGY 16449

Query: 526   TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
             TVQFEC+VEG PRPQI WFR+TAIIKPSQDFQM+YDDDNVATL+IREVFPEDAG FT VA
Sbjct: 16450 TVQFECKVEGNPRPQIAWFRETAIIKPSQDFQMFYDDDNVATLIIREVFPEDAGQFTVVA 16509

Query: 586   KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
             KNAAGF SSTTELIVE+PLSDHGS+ T             ADILEGIPPTFSKKPKAQYV
Sbjct: 16510 KNAAGFTSSTTELIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQYV 16569

Query: 646   DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIESDMHMYCSVLKITNVKKF 703
             DE ++++LECRLVA+PEPDI W F GE+I  +E  N+ +  ESDMHMYCSV+ I+ VKK 
Sbjct: 16570 DENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKS 16629

Query: 704   QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             QEGTY V+A NREGEA LPI LK++T +KE PQ++EPL++M++R+GESV+LS Q+VGNP 
Sbjct: 16630 QEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPP 16689

Query: 764   PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             P +TW K+ KPVK    KSD D H++T++ P+K  ++G YT+KA N  G  ET+A +T+E
Sbjct: 16690 PKVTWYKDGKPVKN--AKSDKDLHTLTLITPQK-SEKGEYTVKAVNPLGSVETTANLTIE 16746

Query: 824   EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
             EP   NAEPPLF+ RF+E  V +KG I+L A+V+ NPVP + W  NN  + PSE I Q +
Sbjct: 16747 EPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVY 16806

Query: 884   DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
             DGENIEL+I + + E DSGDYKC+ASN  GK+SHGARV ++V++VTF K L+K+   EE 
Sbjct: 16807 DGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTFTKKLKKTITIEEV 16866

Query: 944   KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             +++ LEC+TSH V+TKW+ N KE+SGMDHR ++++G+            D G   C VK 
Sbjct: 16867 QSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKK 16926

Query: 1004  QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
             QET + + V +  P+FI+ L+D+EV EKD AIL+VE+ +E  +V W +DGE I P+    
Sbjct: 16927 QETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTEATEVTWYKDGEKITPENKNV 16986

Query: 1064  DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
             +F K G  R+L IR+ ++HDEG+Y+C +  + C+ E+ V+ELPPEI+  L +  V KG  
Sbjct: 16987 EFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVVIELPPEIVEPLNDVAVTKGEN 17046

Query: 1124  ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
             A FE+EL+KGDALV+WFK+G EI F+  IQL IDGKKQ L+I     +D GEYS +VG  
Sbjct: 17047 AVFEVELSKGDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVGEQ 17106

Query: 1184  KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
                A LTVEEP ++F +RLP+  L    TDA  TV++    ++VTW KK   I+  +K  
Sbjct: 17107 TSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQKHE 17166

Query: 1244  LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRG 1302
             +  +   R L+I   +++D  E +CV  +  S+TKL VE ++ PP I  D ++  ++K  
Sbjct: 17167 VFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKEN 17226

Query: 1303  SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
              DVT  V Y   P P   W     +I K K T P+ID +SA LTIKKV + D G Y ++L
Sbjct: 17227 DDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKVVDDDEGEYTVKL 17286

Query: 1363  ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
              N  G A+  +++ I+ KP+ PG P  LEI   SI + W  PE+ G S II Y++EYQ++
Sbjct: 17287 VNPVGEAEASLHLVIMRKPTAPGTPQPLEIMHDSITLYWKAPEDDGKSEIIEYILEYQDV 17346

Query: 1423  DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
                +W  ++ I  T  +I  LK ++ Y FR+ AVNEV  S  S  +   +++ + + ++P
Sbjct: 17347 KEEKWTEIRKIKDTTYTISKLKIDTEYVFRSIAVNEVGPSPPSPLSPPIRLVPKVETKAP 17406

Query: 1483  TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR-XXXXXXXXX 1541
             +V++PL+++ +E ++++ L+C+FGG+P+PKVTW ++G+  ++    YENR          
Sbjct: 17407 SVQEPLQDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYTIEKTT 17466

Query: 1542  XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                   Y C+A N+ G  ETSC + +QQKPV+ + ++ + QK + G    + A + G P 
Sbjct: 17467 IETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQ 17526

Query: 1602  PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
             P V W+K   + +  K   I T E TS   +K++ R  S KY + A+N +GT+ VE T++
Sbjct: 17527 PTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQ 17586

Query: 1662  VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
             V DKPS+P+  + +++I ++S+ +EW PP+DDGGL++ KY +EK +  NN W+KV+D ++
Sbjct: 17587 VIDKPSRPQS-LEIKDIKKDSIVLEWTPPVDDGGLDIEKYTLEKCDVQNNVWMKVSDFNK 17645

Query: 1722  DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
             D+++Y +QKL+ N +YMFRV+A NP+G SE  ES+P+ I    + PS          +++
Sbjct: 17646 DIKSYAVQKLSMNAQYMFRVVAANPIGESEPTESDPVTITKKFEKPSPPRGPTTVSGMND 17705

Query: 1782  ESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKLSINTTYQFR 1838
              S  + W PSE +GGS II+Y VEI++E +   +             ++K+  N  Y FR
Sbjct: 17706 TSFNLAWEPSETDGGSKIIEYIVEIREETETTYRSVGVTLGTVTNIHVEKVVRNKGYFFR 17765

Query: 1839  IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
             IYARNE+GTS  + + +KI +G+ +TPPS P+N    + TSRSVTL W  P  NGGS IT
Sbjct: 17766 IYARNEVGTSEAFETTEKIVLGRKITPPSPPQNLRAPDVTSRSVTLDWEVPARNGGSEIT 17825

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
              Y +E ++    +WTK++T+      + I+N+KEK E  FR+SAEN VG+  P  ++S+ 
Sbjct: 17826 GYCVEKRSSTSTNWTKVITLDAHQLHYTIDNLKEKCEYWFRVSAENEVGLGAPAVTESIS 17885

Query: 1959  LEKHAT--------------------VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
             L+ HA+                    VPSPPT PLE R++ +N  +  WG PE DGGAPL
Sbjct: 17886 LKTHASEFILVVRNCGSYTEFGFLKAVPSPPTGPLEARVLAANAHIFEWGLPESDGGAPL 17945

Query: 1999  LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             LGY+IAIRD+ KTMW+EVG+V    LKF IRDL ENH YMIRI+A+NEIGLSEPLES+EP
Sbjct: 17946 LGYHIAIRDMKKTMWIEVGRVPAGVLKFQIRDLQENHEYMIRIFAKNEIGLSEPLESEEP 18005

Query: 2059  FKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREHNMDADIRSYARGSLLRRDEYF 2118
             +K +        +EP  +TE+             WLR+H+MDADI SYARG LL+RDEYF
Sbjct: 18006 YKAMTAGHESLPDEP--RTEM------SSCNTSSWLRDHHMDADIHSYARGRLLQRDEYF 18057

Query: 2119  FRIW 2122
             FR+W
Sbjct: 18058 FRLW 18061



 Score =  167 bits (406), Expect = 3e-39
 Identities = 166/678 (24%), Positives = 295/678 (43%), Gaps = 68/678 (10%)

Query: 335  DVEKTELEQPLFSYEDIV--ESKKDENEIIQEKQT--LEELPKEDVPEQYTITPRKSSAQ 390
            DV+   + + +   E++V  E   +  +   +K+T  L+E   E  P+   +    +  +
Sbjct: 6351 DVKVVAVSEDVLPEEEVVPTEETPEAKQKAHKKRTKRLKEASVEGQPQ--LLEAAIAEIE 6408

Query: 391  KIDEIVDEV-----TIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGE-R 444
            K+DEI  E+     T+ K+       +   E      V  V   + E     N+++ E R
Sbjct: 6409 KVDEISQEISQKTITLLKKTEDTRPQFITTEQLIELDVEDVRRDL-EMKVTSNIIKKEKR 6467

Query: 445  LYILDTSN---QDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKP 501
              +LD S    +     QK + E    V  + L+++    Q  Q+    ++         
Sbjct: 6468 RVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLIQNQQETTTSEVIGQERKLVK 6527

Query: 502  TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
              +++   P   EKLRP+   P+  TV  EC+VEG P P+I W+    ++  S+ +++  
Sbjct: 6528 KKKKEIKPPRITEKLRPRQCVPEEPTV-LECKVEGVPFPEIKWYFNDILLFASEKYEITV 6586

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
             +  VA L I +V P D G +TC AKN AG A+S T +I+E    + G            
Sbjct: 6587 MEQ-VAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIILE---KEQG------------ 6630

Query: 621  XXXXXADILEGIPPTFSKKPKAQYVDEGS----DILLECRLVAIPEPDIAWLFKGEEIVP 676
                       +PP F+K  K ++++E       + + C++   P P++ W    EE++P
Sbjct: 6631 -----------VPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIP 6679

Query: 677  DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE- 733
             E + +    D       L++ N    +   Y+V A N+ G A  +  I+ ++    +E 
Sbjct: 6680 SETVQMFY--DEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI 6737

Query: 734  -PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
                 + PL +++V  G ++   A+  G PRP + W +N + +          T + T +
Sbjct: 6738 LKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTI 6797

Query: 793  KPKKV--KDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            K   +  K  G Y + A+N  G A++S +V+  ++  +E  +PP FI   +     E   
Sbjct: 6798 KVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEV 6857

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              + A V   P+ S  W+ +NE I  S  +          L+I N  S+   G + C A 
Sbjct: 6858 AIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKF-VGPFTCRAE 6916

Query: 910  NSAGKSSHGARVTI-------DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKW 960
            N  G  +  A V +       + E   FV+ L +  E  +G+ ++L CQ +   T   +W
Sbjct: 6917 NVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEW 6976

Query: 961  YHNKKEISGMDHREIIQE 978
            YHN ++I+      I Q+
Sbjct: 6977 YHNAEKITENKETTISQD 6994



 Score =  149 bits (361), Expect = 8e-34
 Identities = 116/436 (26%), Positives = 192/436 (44%), Gaps = 45/436 (10%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+F +K++P    +    +FE + EG P P + W+R++  I+ S D Q++      + L
Sbjct: 4393 APVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGK-SIL 4451

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            +IR+VF ED+  F+CVA+N  G A  +  L+V E   +  G                   
Sbjct: 4452 IIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQ---------------- 4495

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
                 PP+F    ++  V  G     + ++      D+ WL  G +I P     +  E  
Sbjct: 4496 -----PPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDS 4550

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----------GEKEPPQV 737
            +H     L I        G Y  VAVN  GEA       +++          G ++ P +
Sbjct: 4551 VH----TLLIIEPFAEDSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHI 4606

Query: 738  IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794
            +E LKS  V +G  VI   +V G P PT  W +     KP +       G+ + + ++  
Sbjct: 4607 VEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQMSRQGEYYQL-VISE 4665

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
               +DEG Y   AEN  G  +TSA + V  P  EN + P  I   ++++V E    +   
Sbjct: 4666 AFPEDEGTYKCVAENKLGSIQTSAQLKV-RPI-ENLDAPPTITALKDVSVTEGMPAQFKT 4723

Query: 855  RVT-RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             VT +    S+ W+R  ++I  +      FDG +  L+I     E DSG +    ++S G
Sbjct: 4724 TVTGKVKATSVQWFREGQLIPETPDFQMIFDGNSAVLLIGTTYEE-DSGIFTVRVTSSTG 4782

Query: 914  KSSHGARVTIDVEKVT 929
            +    A++T+   +++
Sbjct: 4783 QVESSAKLTVKKRRIS 4798



 Score =  144 bits (350), Expect = 2e-32
 Identities = 124/436 (28%), Positives = 201/436 (46%), Gaps = 45/436 (10%)

Query: 504  EEQSMAPIFVEKLR----PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            +EQ + P F + L+     +  P+   V   CQV G P P++ W+R    + PS+  QM+
Sbjct: 6627 KEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMF 6686

Query: 560  YDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
            YD+   +VA  VI    P +A  ++  A+N  G A     ++          E+      
Sbjct: 6687 YDEKTGDVALEVINPT-PNEAVVYSVQAQNQFGRAIGNANILSRV------DEVP----- 6734

Query: 618  XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
                     +IL+   PT +    A  V  G  +  E +   +P P++ W+  G EI+  
Sbjct: 6735 --------REILKA--PTVTPL-SAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREII-- 6781

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEK-E 733
            EN    IE+      + +K+ N+ + + G Y V A N+ GEA      +V   K  E+ +
Sbjct: 6782 ENEETIIETTETT--TTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIK 6839

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITIL 792
            PP+ I+PL+     + E  I+ A V   P  +  W  +N+P+K+    +     +  T+L
Sbjct: 6840 PPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLL 6899

Query: 793  KPK-KVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGT 849
                + K  G +T +AEN  G +  T+ V  + +   E  E P F+    Q + V +   
Sbjct: 6900 IENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEA 6959

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCV 907
            + L  +VT  P P + WY N E I+ ++  TI+Q+  G   +L IT V  E + G Y+CV
Sbjct: 6960 LLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGV-CQLQITEVFPE-NEGQYECV 7017

Query: 908  ASNSAGKSSHGARVTI 923
            A+N  GKS     V I
Sbjct: 7018 ATNKIGKSVSKTNVKI 7033



 Score =  140 bits (339), Expect = 4e-31
 Identities = 97/359 (27%), Positives = 162/359 (45%), Gaps = 15/359 (4%)

Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           L+ E ++ + + ++   + D     E   ++  + AP   +K R     +GS   F  +V
Sbjct: 219 LLREVSFREAITRRSGYEQDSQLSQELDRNQGPAQAPQISQKPRSSKLIEGSDAVFTARV 278

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
              P+P++TWF     +  SQ +++ Y    VATL ++     D G +T +A+N  G   
Sbjct: 279 GSNPKPRLTWFHNGQRLVASQKYEISYSS-GVATLRVKNATARDGGHYTLLAENLQGCVV 337

Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653
           S+  L VE P ++   E               A     +PP F K    + + EG     
Sbjct: 338 SSAVLAVE-PAAETAYEPKPVDVMAEQLEAGKA-----LPPAFVKAFGDREITEGRMTRF 391

Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVA 712
           +CR+   P P++ WL  G ++  D +  + + ES  H     L ITNV +   G    +A
Sbjct: 392 DCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHS----LMITNVTRLDAGAVQCLA 447

Query: 713 VNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
            N+ GE ++   L +   E+   PQ ++   +M VR+GE + +SA  +G P+P ITW K+
Sbjct: 448 RNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKD 507

Query: 772 NKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
              + +   +  G     T L+  +V   D G Y   A+N  G     A + VE P E+
Sbjct: 508 GVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQ 566



 Score =  115 bits (276), Expect = 2e-23
 Identities = 119/528 (22%), Positives = 215/528 (40%), Gaps = 43/528 (8%)

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            ELI +  L  +  E T                 E  PP  ++K + +        +LEC+
Sbjct: 6499 ELIEDQQLIQNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECK 6558

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +  +P P+I W F    +   E   + +   +    + LKI  V     G YT  A N  
Sbjct: 6559 VEGVPFPEIKWYFNDILLFASEKYEITVMEQV----AKLKIAKVTPSDVGVYTCEAKNEA 6614

Query: 717  GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----SVILSAQVVGNPRPTITWCKN- 771
            G A+    + ++  +  PPQ  +PLK   + + +     V ++ QV G P P + W +  
Sbjct: 6615 GVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGI 6674

Query: 772  -----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEE 824
                 ++ V+    +  GD  ++ ++ P    +  VY+++A+N  G  I   + +  V+E
Sbjct: 6675 EEVIPSETVQMFYDEKTGDV-ALEVINPTP-NEAVVYSVQAQNQFGRAIGNANILSRVDE 6732

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNF 883
               E  + P  +     + V   GT+   A+    P P + W RN  EII   ETI +  
Sbjct: 6733 VPREILKAPT-VTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETT 6791

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTID------VEKVTFVKHLQK 936
            +     + + N+  +  +G Y+  A N  G++ S G+ V  D      ++   F++ L+ 
Sbjct: 6792 E-TTTTIKVVNMTRK-RTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEP 6849

Query: 937  SYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
             Y  E    +I     S  +S+ +W+ + + I   +   I+ +               VG
Sbjct: 6850 KYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVG 6909

Query: 996  VIKCIVKD---QETSTM---LVVKETI-----PEFIRKL-QDFEVKEKDVAILEVEINSE 1043
               C  ++     TST    L+ +E       P F+ +L Q  EV + +  +L  ++  +
Sbjct: 6910 PFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGK 6969

Query: 1044 -TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
             T  V W  + E I   K     +    + +L I      +EG+Y C+
Sbjct: 6970 PTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECV 7017



 Score =  109 bits (263), Expect = 6e-22
 Identities = 81/318 (25%), Positives = 140/318 (44%), Gaps = 32/318 (10%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P  S+KP++  + EGSD +   R+ + P+P + W   G+ +V  +   ++  S +    +
Sbjct: 255 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGV----A 310

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVL--------------------KIKTGEKE 733
            L++ N      G YT++A N +G      VL                    +++ G+  
Sbjct: 311 TLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKAL 370

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSI 789
           PP  ++      + +G       +V GNP P + W  N + V+   +     ++  +HS+
Sbjct: 371 PPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSL 430

Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            I    ++ D G     A N  G     A + V E  +E    P F+ RF  +TV+E   
Sbjct: 431 MITNVTRL-DAGAVQCLARNKAGEVAIEAQLNVLE--KEQVVAPQFVQRFSTMTVREGEP 487

Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
           I + A     P P ITW ++   IS +       DG    L I  V +  D+G Y+C A 
Sbjct: 488 ITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTAN-DAGWYQCTAQ 546

Query: 910 NSAGKSSHGARVTIDVEK 927
           N AG +++ AR+ ++V +
Sbjct: 547 NIAGSTANRARLYVEVPR 564



 Score =  109 bits (262), Expect = 8e-22
 Identities = 153/648 (23%), Positives = 251/648 (38%), Gaps = 98/648 (15%)

Query: 480  YTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538
            Y  + + K+ E K     V      +EQ   P F++ L PK+  +      E  VE  P 
Sbjct: 6810 YEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPL 6869

Query: 539  PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
                WF     IK S + ++     N +TL+I     +  G FTC A+N  G  +ST  +
Sbjct: 6870 SSFQWFVHNEPIKSSNEVRIV-SQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATV 6928

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
             +  P  +                   A+  E  P    +  +   V +G  +LL C++ 
Sbjct: 6929 NL-IPQEE-------------------AEEFES-PRFVEELVQPVEVMDGEALLLTCQVT 6967

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
              P P + W    E+I   EN    I  D+   C  L+IT V    EG Y  VA N+ G+
Sbjct: 6968 GKPTPKVEWYHNAEKIT--ENKETTISQDLQGVCQ-LQITEVFPENEGQYECVATNKIGK 7024

Query: 719  ASLPIVLKIK-------------TGEKEP------------PQVIEPLKSMIV-RQGESV 752
            +     +KI+             TG +E             P++I+ L   I  ++GE  
Sbjct: 7025 SVSKTNVKIQAFEYIPDSEITGLTGSEEDLLDRTLSIDEQAPKIIKKLPEKIEPKEGEQA 7084

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L  +VVG P+P + W ++++ + A      ++  D  S+ ++      D G  + +A N
Sbjct: 7085 KLEVKVVGKPKPKVKWLRDDEQIFASEEYQIENFEDGTSVLVINHVYPDDLGTISFEAYN 7144

Query: 810  SEGIAETSAVITVEEPT-EENAEPPLFINRFQEITVKEKG-------------------- 848
              G+A T+A+  VE     ++   P ++++ +E+ V  K                     
Sbjct: 7145 PLGVAVTTALFAVEGIVGSKDYRKPEWVSQMEEMQVALKAAKCSPSLLNEMRDCRAALGE 7204

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            T K   +   NP+P I WY NN  +  SE        +   L I  + SE D G Y C  
Sbjct: 7205 TAKFSIQFAGNPIPDIQWYFNNVQLRASEKYRMVVQEQEATLEIMKITSE-DCGYYNCKL 7263

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
             N  G +    R   D+   + +       E  + KT + +     T+  +   ++ +  
Sbjct: 7264 INEIGMTM--TRAKFDISSTSTI------VEETKAKTTVKKKSGKKTMVKRSGASESQNV 7315

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028
                  II                 V V   +V+  E S +LVVK+      R++ D E 
Sbjct: 7316 QKTEIRIIPTSAVETSMNVIKVKQPVSV---LVEKSEISEVLVVKD------REVADAEE 7366

Query: 1029 KEKDVAILEVEINSETADVVW---ERDGEIIKPKKNKYDFEKRGHIRK 1073
            +   + I E+E   E  + V    E + E+   +K  Y   K+  I K
Sbjct: 7367 RSSQL-IEEIEEEEEIEEKVQHDEEDEVEVQVEQKETYTSSKKIEITK 7413



 Score =  101 bits (243), Expect = 2e-19
 Identities = 100/395 (25%), Positives = 162/395 (41%), Gaps = 33/395 (8%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITIL 792
            P   + ++   V + E      +  G P PT+ W + + P++  P          SI I+
Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 4453

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEE---PTEENAEPPLFINRFQEITVKEKGT 849
            +   V+D  V++  AEN  G A+ SA + VEE     +   +PP F+   Q  TV     
Sbjct: 4454 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 4513

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
             +  A+VT      + W +N   I PS       +     L+I    +E DSG Y+CVA 
Sbjct: 4514 ARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE-DSGRYECVAV 4572

Query: 910  NSAGK------------SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHT 955
            N+AG+            S      T   EK   +    KS   EEG  VI  C+     T
Sbjct: 4573 NAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPT 4632

Query: 956  VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLV 1011
             + +W   +  +    + ++ ++G             D G  KC+ +++    +TS  L 
Sbjct: 4633 PTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLK 4692

Query: 1012 VK--ETI--PEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPKKNKYDF 1065
            V+  E +  P  I  L+D  V E   A  +  +    +   V W R+G++I P+   +  
Sbjct: 4693 VRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLI-PETPDFQM 4751

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
               G+   L I  T   D G ++  +R  S T +V
Sbjct: 4752 IFDGNSAVLLIGTTYEEDSGIFT--VRVTSSTGQV 4784



 Score =  100 bits (239), Expect = 5e-19
 Identities = 92/367 (25%), Positives = 160/367 (43%), Gaps = 36/367 (9%)

Query: 676  PDENISVAIESDMHMYCSVLKITNVKKFQ-----EGTYTVVAVNREG---EASLPIVLKI 727
            P +N+   I S+ + Y S+ +   V  F+     E ++      R G   ++ L   L  
Sbjct: 188  PIQNLEKNIYSNGYSYTSIEEEFRVDTFEYRLLREVSFREAITRRSGYEQDSQLSQELDR 247

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
              G  + PQ+ +  +S  + +G   + +A+V  NP+P +TW  N + + A        + 
Sbjct: 248  NQGPAQAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSS 307

Query: 788  SITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE---------EPTEENAE----- 831
             +  L+ K    +D G YTL AEN +G   +SAV+ VE         +P +  AE     
Sbjct: 308  GVATLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAG 367

Query: 832  ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGE 886
               PP F+  F +  + E    +   RVT NP P + W  N   +    S  I  N  G 
Sbjct: 368  KALPPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGS 427

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQK--SYETEEG 943
            +  L+ITNV + +D+G  +C+A N AG+ +  A++ + + E+V   + +Q+  +    EG
Sbjct: 428  H-SLMITNV-TRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 485

Query: 944  KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            + + +      T   +  W  +  +IS    R +  +G             D G  +C  
Sbjct: 486  EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 545

Query: 1002 KDQETST 1008
            ++   ST
Sbjct: 546  QNIAGST 552



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 100/423 (23%), Positives = 160/423 (37%), Gaps = 30/423 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+KK +   V E      E      P P + W     E  P +N S  ++       S
Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWY---RESFPIQN-SPDLQIHTFSGKS 4449

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT------GEKEPPQVIEPLKSMIVR 747
            +L I  V       ++ VA NR G A     L ++       G  +PP  +  ++S  V 
Sbjct: 4450 ILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVA 4509

Query: 748  QGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
             G+     A+V G     + W KN    +P        +   H++ I++P   +D G Y 
Sbjct: 4510 TGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEP-FAEDSGRYE 4568

Query: 805  LKAENSEGIAETSAVITV------EEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVT 857
              A N+ G A       V      E+PT   +E  P  + + +  TV+E   +    RV 
Sbjct: 4569 CVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVD 4628

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              P P+  W R    + PS     +  GE  +LVI+    E D G YKCVA N  G    
Sbjct: 4629 GKPTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPE-DEGTYKCVAENKLGSIQT 4687

Query: 918  GARVTI-DVEKVTFVKHLQ--KSYETEEGKTVILECQTSHTV---STKWYHNKKEISGMD 971
             A++ +  +E +     +   K     EG     +   +  V   S +W+   + I    
Sbjct: 4688 SAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLIPETP 4747

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
              ++I +G             D G+    V           K T+ +  R++  F+++  
Sbjct: 4748 DFQMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVKK--RRISAFQLRTI 4805

Query: 1032 DVA 1034
            D A
Sbjct: 4806 DSA 4808



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 12/178 (6%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            EKPT+     AP  VE+L+ +   +GS V F C+V+G P P   W R    +KPS+ FQM
Sbjct: 4593 EKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQM 4652

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618
                +    LVI E FPED GT+ CVA+N  G   ++ +L V  P+ +  +  T+     
Sbjct: 4653 SRQGE-YYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVR-PIENLDAPPTI----- 4705

Query: 619  XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE-PDIAWLFKGEEIV 675
                     + EG+P  F      +          E +L  IPE PD   +F G   V
Sbjct: 4706 --TALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQL--IPETPDFQMIFDGNSAV 4759



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 111/482 (23%), Positives = 194/482 (40%), Gaps = 58/482 (12%)

Query: 774  PVKALPTKSDGDTHS--ITILKPKKVKDEGVYTLKAENSEGIAETSAVI---TVEEPTEE 828
            P K +   S+   H   + + K ++V+ E    L+        ET+ V    T++E   +
Sbjct: 4326 PPKGIAQPSESSVHGREVHMNKQQQVQKEIQGDLEITRKITATETTEVEHKGTIQERVVQ 4385

Query: 829  N----AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNF 883
                 A+ P+F  + Q   V E    K        P P++ WYR +  I  S  +    F
Sbjct: 4386 GPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTF 4445

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHL 934
             G++I L+I  V  E DS  + CVA N  G +   A + ++         ++  +FV  +
Sbjct: 4446 SGKSI-LIIRQVFVE-DSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTI 4503

Query: 935  QKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
            Q S     G+    + + + T  +   W  N  +I      ++++E              
Sbjct: 4504 Q-STTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE 4562

Query: 993  DVGVIKCIVKDQETSTML----VVK-------------ETIPEFIRKLQDFEVKEKDVAI 1035
            D G  +C+  +           +V+             E  P  + +L+   V+E    I
Sbjct: 4563 DSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVI 4622

Query: 1036 LEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
                ++ + T    W R    +KP +  +   ++G   +L I      DEG Y C+  ++
Sbjct: 4623 FRCRVDGKPTPTARWMRGENFVKPSRY-FQMSRQGEYYQLVISEAFPEDEGTYKCVAENK 4681

Query: 1095 ------SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELT-KGDAL-VRWFKDGS 1144
                  S   +V  +E    P  IT L++  V +G  A F+  +T K  A  V+WF++G 
Sbjct: 4682 LGSIQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQ 4741

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSIN-FT 1199
             I  +   Q+  DG    L I     +D+G ++  V    G  + +A LTV++  I+ F 
Sbjct: 4742 LIPETPDFQMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVKKRRISAFQ 4801

Query: 1200 LR 1201
            LR
Sbjct: 4802 LR 4803



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 129/648 (19%), Positives = 257/648 (39%), Gaps = 57/648 (8%)

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
            + +++G+ Q L+    +++   E S E+     T +   E+    F +   + I +    
Sbjct: 6390 EASVEGQPQLLEAAIAEIEKVDEISQEISQKTITLLKKTEDTRPQF-ITTEQLIELDVE- 6447

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCVL 1270
            D    +E+   +  +   K++ V++D++    +  + ++ +   I K  +++  E   ++
Sbjct: 6448 DVRRDLEMKVTSNIIKKEKRRVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLI 6507

Query: 1271 LDAKSTTKLKV-----EVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319
             + + TT  +V     ++V+       PP+I +  R  +        L    +  P P  
Sbjct: 6508 QNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECKVEGVPFPEI 6567

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +W  N  ++   +  + ++  + A L I KV  +D G+Y    +N  G A    N+ IL+
Sbjct: 6568 KWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNI-ILE 6626

Query: 1380 KPS--PPGKPNILEIDSSSINICWDEPEN---------TG--NSTIIYY--VVEYQEIDT 1424
            K    PP     L+I+     I   +PE          TG  N  + +Y  + E    +T
Sbjct: 6627 KEQGVPPQFTKPLKIEF----IEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSET 6682

Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSP 1482
             +    +        + N   N +  +   A N+    I +A+  +   +V +E  +++P
Sbjct: 6683 VQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI-LKAP 6741

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXX 1538
            TV  PL  +       +     + G+P+P+V W R+G+++    +T   T E        
Sbjct: 6742 TVT-PLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVV 6800

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKVGDE-WLV 1592
                     Y+  A N  GE ++S  VV   QKP   I      + ++ K+    E  ++
Sbjct: 6801 NMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAII 6860

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             A++E  P     W+ +   +++  E  I ++   S + I+  +      +T  A N  G
Sbjct: 6861 EAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGG 6920

Query: 1653 --TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
              TS+  V L   ++  + E P  + E+      ++    +D   L LT     K  P  
Sbjct: 6921 SVTSTATVNLIPQEEAEEFESPRFVEEL------VQPVEVMDGEALLLTCQVTGKPTPKV 6974

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
              +     +  + ET   Q L   C+     +     G  E + +  I
Sbjct: 6975 EWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKI 7022



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 90/403 (22%), Positives = 160/403 (39%), Gaps = 46/403 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRK-- 1073
            P F +K+Q   V E + A  EVE   E    V W R+     P +N  D +      K  
Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESF---PIQNSPDLQIHTFSGKSI 4450

Query: 1074 LYIRNTSVHDEGEYSCILRDES----CTAEVTVVEL---------PPEIITRLQNQKVNK 1120
            L IR   V D   +SC+  +      C+A + V E          PP  +T +Q+  V  
Sbjct: 4451 LIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVAT 4510

Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178
            G  A F+ ++T    L V W K+G +IQ S   ++  +     L I +   +D+G Y C 
Sbjct: 4511 GQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 4570

Query: 1179 ---EVGNSKCTAILTV------EEPSINFTLRLPEFI------LVPANTDAYLTVEIPDE 1223
                 G ++C     V      E+P+   + + P  +       V   +       +  +
Sbjct: 4571 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 4630

Query: 1224 -TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTK 1278
             T    W + ++ ++ +  F +    +   L+I +   +D+  Y CV    L   +++ +
Sbjct: 4631 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 4690

Query: 1279 LKVEVVE---FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHT 1334
            LKV  +E    PP I    ++  +  G             +    +W    ++I +    
Sbjct: 4691 LKVRPIENLDAPPTITAL-KDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLIPETPDF 4749

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            +   D  SA L I      D+GI+ +R+ ++ G  +    +T+
Sbjct: 4750 QMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTV 4792



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 75/323 (23%), Positives = 131/323 (40%), Gaps = 35/323 (10%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P    ++Q  +V +  +A FE+E   + +  V+W+++   IQ S  +Q+     K  L I
Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 4453

Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEP--SINFTLRLPEFILVPANT------- 1212
                ++D+  +SC      G +KC+A L VEE   +    ++ P F+    +T       
Sbjct: 4454 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 4513

Query: 1213 ---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
               DA +T   P   LDV W K    I+ + KF ++ +    TL+I +   +D   Y CV
Sbjct: 4514 ARFDAKVTGTRP---LDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 4570

Query: 1270 LLDAKSTTKLKVE-VVEFP--------------PKIVDYEREYRIKRGSDVTLLVDYQAF 1314
             ++A    +   + +V+ P              P IV+  +   ++ GS V         
Sbjct: 4571 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 4630

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P   W+     +K  ++ + S   +   L I +    D G YK   EN  G       
Sbjct: 4631 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 4690

Query: 1375 VTILDKPSPPGKPNILEIDSSSI 1397
            + +    +    P I  +   S+
Sbjct: 4691 LKVRPIENLDAPPTITALKDVSV 4713



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 76/249 (30%), Positives = 125/249 (50%), Gaps = 21/249 (8%)

Query: 160   DSQEDESKPDVSQPPQNIIEEAKSEPKLIEES-EQPIAKTSEIDNEVPEKINVPDDKETS 218
             ++ ED +KP  S+  + + ++     +LI++  EQ I KT   + E  EKI     K+  
Sbjct: 14724 ETVEDVTKPK-SKKKKVVKKKTDDHDELIKKMLEQEIEKT---ELEKYEKIEFDVPKKLK 14779

Query: 219   QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278
                    + + L PIKIERKE + +     +  D P+               E + V+LP
Sbjct: 14780 P------EFAALEPIKIERKEQKPTKVTILDATDVPKTVKLKPSKRKEKPAEELT-VQLP 14832

Query: 279   KFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVE- 337
             KF+LK+R+  +  +PP  + P  + +G+IK NG LSRNI+EA ++ K  F P K   ++ 
Sbjct: 14833 KFRLKARM-VLVEYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILK--FKPHKTKKIKK 14889

Query: 338   -KTELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQ-KID 393
              K +LE+  L  YE  + S+++  E    K+  E+ PK E+  E   +   K   + K +
Sbjct: 14890 IKDDLEKVELEKYEKYISSEEEPEEKTPYKKP-EKAPKPEEKQEDVKLKLGKGKKKPKEE 14948

Query: 394   EIVDEVTIK 402
             E  + VT+K
Sbjct: 14949 EAPENVTLK 14957



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 88/343 (25%), Positives = 148/343 (43%), Gaps = 30/343 (8%)

Query: 83    EPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXX-----XX 137
             E   V+LPKF+LK+R+  + ++PP  + P  T +G+IK NGELSRN++EA          
Sbjct: 14825 EELTVQLPKFRLKARMVLV-EYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILKFKPHK 14883

Query: 138   XXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAK 197
                      DLE+V LEK + + S E+E  P+   P +   +  K E K  E+ +  + K
Sbjct: 14884 TKKIKKIKDDLEKVELEKYEKYISSEEE--PEEKTPYKKPEKAPKPEEKQ-EDVKLKLGK 14940

Query: 198   TSE--IDNEVPEKINVPDDKETSQTPTSFNKRSKL--TPIKIERKEMEVSTPQHAETVDG 253
               +   + E PE + +   K   Q P    +  +L   P ++E  E +   P+  E V  
Sbjct: 14941 GKKKPKEEEAPENVTL---KNIPQKPQEVEEEVELKQKPKEVEIVEEQTKKPKDGEFVVE 14997

Query: 254   PQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGIL 313
             P                E   ++ P+   K +    T + P+      S   +I    + 
Sbjct: 14998 P--FEPSEFDRPEYVPDELEQIEHPEIPEKVKKPSKTKYKPKDKSK--SEPETIVSEIVA 15053

Query: 314   SRNIKEAAKVKKQV-FVPPKLPDVEKTELEQPLFSYEDIVESKKDEN---EIIQEKQTLE 369
                 +E A  ++ V F  P+    E+T+ E  L     + ++ KDEN   + +   +  E
Sbjct: 15054 GVPKEEEAIPEQDVKFRKPERDAPEETDSEIKL---RPVPQASKDENPDEQALVTPKAEE 15110

Query: 370   ELPK--EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEI 410
              +P+  ED        P+KS  +K+     E+  K+    FE+
Sbjct: 15111 PIPQEIEDKAIDDEKKPKKSKPKKVQPKEQEIA-KEEPEEFEV 15152



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 89/363 (24%), Positives = 145/363 (39%), Gaps = 57/363 (15%)

Query: 520  HTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
            +T +G    FEC++E    P  ++ WF+    I     F+  +D   VA L I  +  ED
Sbjct: 1435 NTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHDFGYVA-LDIVHLIAED 1493

Query: 578  AGTFTCVAKNAAGFASSTTEL-------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630
            +G +TC A N  G   +  EL       IV    ++ G E  +             +I E
Sbjct: 1494 SGVYTCRAVNLIGSDETQVELQCRSGEQIVTVTQNEAGLEQ-IHYLEDRSRYTRREEIDE 1552

Query: 631  GIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIES 686
                 P F+   K   + E      ECRL+ + +P   + W       +P ++ S   E+
Sbjct: 1553 STKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNN---LPLKSGSRFTET 1609

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREG----------------------EASLPIV 724
            +   + + L I +      GTYT  A N  G                      E +LP +
Sbjct: 1610 NNFGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRL 1668

Query: 725  LKIKTGEK------------EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCK 770
              ++ G K            + P    P++ + V + ++V   A++  VG+P+ T+ W +
Sbjct: 1669 QHLEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLR 1728

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            N +P++A    +         L  K V  +D G YT +A N  G A TSA + V+  T  
Sbjct: 1729 NGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSI 1788

Query: 829  NAE 831
              E
Sbjct: 1789 QLE 1791



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 22/262 (8%)

Query: 484  LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQ 540
            L+K  N +   +   E+ T E +  AP+F   L   ++  +G    FE ++     P+ +
Sbjct: 3375 LEKIANLEYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLK 3434

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            + W+     +K    F+ + D   V  L I  V+PED+G ++C A N  G A +T  + +
Sbjct: 3435 VEWYWNGRPLKAGSRFRTFCDFGFVI-LEISPVYPEDSGEYSCRAINEYGEAVTTATMKI 3493

Query: 601  EAPLS-------DHGSEMTVXXXXXXXXXXXXA-----DILEGIPPTFSKKPKAQYVDEG 648
            +   S         G E T+            +     D   G PP F   P    + E 
Sbjct: 3494 QGKRSIIMESQLPKGMEGTIDRIAELEGLGSRSTEFVPDDDTGKPPEFITSPFDMVIGEN 3553

Query: 649  SDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            +    ECRL  I +P   + W   G+ +     I     +D      +L+I    +   G
Sbjct: 3554 ALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTI--NDFGFV--ILEIAGCYQRDSG 3609

Query: 707  TYTVVAVNREGEASLPIVLKIK 728
             YT  A N+ GEA++   L++K
Sbjct: 3610 LYTCKATNKHGEATVSCKLQVK 3631



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 102/523 (19%), Positives = 208/523 (39%), Gaps = 34/523 (6%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKV 1281
            ++ WY    ++  +EK+ +    +   L I K T  D   YTC   +    A S T + +
Sbjct: 6566 EIKWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIIL 6625

Query: 1282 EVVE-FPPKI-----VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            E  +  PP+      +++  E + +R   VT+       P P  +W    + +   +  +
Sbjct: 6626 EKEQGVPPQFTKPLKIEFIEEKQPER-LKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQ 6684

Query: 1336 PSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNVT--ILDKPSPPGK-PNIL 1390
               D K+  + ++ +  T  +A +Y ++ +N  G A    N+   + + P    K P + 
Sbjct: 6685 MFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREILKAPTVT 6744

Query: 1391 EIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
             + +  +      + E +  G     + +     + I+  E I     T T   + N+  
Sbjct: 6745 PLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTR 6804

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
              + ++  +A N+V  + +S +        + +I+ P   +PL+      +E   +  I 
Sbjct: 6805 KRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIV 6864

Query: 1506 GGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
               P     W+   + +K++      +  N+               + C A N  G V +
Sbjct: 6865 ESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTS 6924

Query: 1562 SCVVG-IQQKPVITISN----EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            +  V  I Q+      +    E++ Q  +V  G+  L+T  + G P P+V WY N  K+ 
Sbjct: 6925 TATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKIT 6984

Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
             +KE  I+   +    ++I E+   +  +Y   A+N  G S  +  +K+      P+  +
Sbjct: 6985 ENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKIGKSVSKTNVKIQAFEYIPDSEI 7044

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
                 S E + ++    +D+   ++ K   EK EP      K+
Sbjct: 7045 TGLTGSEEDL-LDRTLSIDEQAPKIIKKLPEKIEPKEGEQAKL 7086



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 61/269 (22%), Positives = 106/269 (39%), Gaps = 20/269 (7%)

Query: 498  FEKPTSEEQSM--APIFVEKL-RPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKP 552
            +++   EE ++  AP+FV KL  P +  +G +  +EC++E YP P  ++ WF     +  
Sbjct: 1810 YQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKPLST 1869

Query: 553  SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--------SSTTELIVEAPL 604
               F+  YD    A L I  V+ ED+G +TC   N  G A        +S + +I E   
Sbjct: 1870 GHRFRTTYDF-GFAALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNVTSRSSIIHETQH 1928

Query: 605  SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP- 663
             +  +++               +      P F +  +   V+EG+ + LE  L+ + +P 
Sbjct: 1929 EEALTKIQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPT 1988

Query: 664  -DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722
              + W   G  I          +         L I        GTY   A N  GEA   
Sbjct: 1989 MKVEWYCNGRPIQTGHRFKTTYDFGF----VALDILYAHAEDTGTYMCKAKNAIGEAVTT 2044

Query: 723  IVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              + +   +      ++  +   +RQ E+
Sbjct: 2045 CAVNVTANKTLDLDTLDAQRLEKIRQLET 2073



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 67/257 (26%), Positives = 105/257 (40%), Gaps = 24/257 (9%)

Query: 481  TQYLQKKLNEKIDKLP--VFEKPTSEEQSMA---PIFVEKLR-PKHTPDGSTVQFECQVE 534
            T  + + L EK   L    F +P  + + ++   P+FV  L  PK   DG  +  EC++E
Sbjct: 1124 TSSMHRGLYEKTQNLENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLE 1183

Query: 535  --GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
              G P  ++ WF     +     F+ YYD   VA  +I+     D+G +T  A N  G A
Sbjct: 1184 PMGDPTMRVEWFHNGRPVTVGSRFRTYYDFGFVALDIIKAT-AADSGEYTVRATNHLGTA 1242

Query: 593  SST--------TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
             ++        T+++ E   ++   E                DI     P F++      
Sbjct: 1243 HTSACVRVIDHTDVVTETQ-NEQSLEQIQLLEDSRRRHHQEEDITIMQAPQFTRGLHNIE 1301

Query: 645  VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
              EG+++ LECRL  + +P   I W   G+ +        A E D   Y + L +     
Sbjct: 1302 TIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFD---YVA-LDLLGCYA 1357

Query: 703  FQEGTYTVVAVNREGEA 719
               G YT  A N+ GEA
Sbjct: 1358 IDSGVYTCQARNQLGEA 1374



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 93/376 (24%), Positives = 150/376 (39%), Gaps = 56/376 (14%)

Query: 496  PVFEKPTSEEQSMA-PIFVEKLR-PKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIK 551
            P+  +PT  E+    PIF + L  P    +G+   FE +V   G P  +  WF     ++
Sbjct: 2473 PLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSLKFEWFINGVELQ 2532

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
                 +  +D   V TL I  V PEDAG + C A NAAG A S+T + V+   +  G  +
Sbjct: 2533 MGSRLRTTHDFGFV-TLDITAVVPEDAGVYMCRAYNAAGEAVSSTAMKVKTKSNIDGQPL 2591

Query: 612  TVXXXXXXXXXXXXAD-----ILEGIP---PTFSKKPKA-QYVDEGSDILLECRLVAIPE 662
                           +      ++  P   P F+   ++   + EG  +LLE ++    +
Sbjct: 2592 IPESWEAIRLKEAAMNRVPEMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRAD 2651

Query: 663  PD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA- 719
            P+  I W   G  +         I S        L I  ++      YT  A N+ GEA 
Sbjct: 2652 PNLRIEWFKNGISLTTGSR----IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAV 2707

Query: 720  ---------------------SLPIVLKIKTGEKEPPQVIEP----------LKSMIVRQ 748
                                 SLP + +++  ++  P+  EP          L ++  ++
Sbjct: 2708 STSSLKIEDRHWLQAESLHPDSLPRIGELEAPKEGRPEAPEPTYETPVFITHLNNIECKE 2767

Query: 749  GESVILSAQV--VGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYT 804
             ++V     V    +P  +I W  N +P++A    KS  D     + L     ++ GVYT
Sbjct: 2768 SDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCALDLTNSYAENSGVYT 2827

Query: 805  LKAENSEGIAETSAVI 820
             KA NS+G A TS  +
Sbjct: 2828 CKATNSKGSATTSGTL 2843



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 60/238 (25%), Positives = 97/238 (40%), Gaps = 20/238 (8%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            AP F   L    T +G+ V  EC+++  G P  +I WF     +K    F+  Y+ D VA
Sbjct: 1290 APQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYVA 1349

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASST--------TELIVEAPLSDHGSEMTVXXXXX 618
             L +   +  D+G +TC A+N  G A ++         +LI+E        ++       
Sbjct: 1350 -LDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQKIQYLEDST 1408

Query: 619  XXXXXXXADILEGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIV 675
                    D +  I P F   PK+     EG     EC++  + +P+  + W   G  I 
Sbjct: 1409 RHRRSEFVDEVVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPIT 1468

Query: 676  PDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
                        +H +  V L I ++     G YT  AVN  G     + L+ ++GE+
Sbjct: 1469 VGHRFR-----PIHDFGYVALDIVHLIAEDSGVYTCRAVNLIGSDETQVELQCRSGEQ 1521



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 61/241 (25%), Positives = 95/241 (39%), Gaps = 21/241 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            E    AP+F   L+     +     FEC++     P  ++ W+     +K    F    +
Sbjct: 1552 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 1611

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL-----SDHGSEMTVXXX 616
               VA L I    PEDAGT+TC A NA G A ++   +V         S H + +     
Sbjct: 1612 FGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRLQH 1670

Query: 617  XXXXXXXXXADILEGI---PPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAWLFKG 671
                       + +      P F+   +   V E   +  E RL+ + +P   + WL  G
Sbjct: 1671 LEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNG 1730

Query: 672  EEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIK 728
            + I      +      MH +  V L +  V     GTYT  AVN  G+A  S  ++++ K
Sbjct: 1731 QPIEASNRTTT-----MHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSK 1785

Query: 729  T 729
            T
Sbjct: 1786 T 1786



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 18/234 (7%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            S AP+F   +R     +   V FE ++   G P+  + W R    I+ S      +D   
Sbjct: 1688 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 1747

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGSEMTVXXXXXX 619
            VA L ++ V PED+GT+TC A N  G A ++  LIV++  S      H + M        
Sbjct: 1748 VA-LNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSIQLETQHEAAMHKIHQLED 1806

Query: 620  XXXXXXADILE---GIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
                   +  E      P F +K      + EG     ECR+   P+P+  + W   G+ 
Sbjct: 1807 HSRYQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKP 1866

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
            +          +       + L I  V     G YT    N  GEA   IVL +
Sbjct: 1867 LSTGHRFRTTYDFGF----AALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNV 1916



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 107/485 (22%), Positives = 186/485 (38%), Gaps = 59/485 (12%)

Query: 947  ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
            +LEC+         KWY N   +   +  EI    +            DVGV  C  K++
Sbjct: 6554 VLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNE 6613

Query: 1005 ------ETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETA-----DVVWERD 1052
                   T+ +L  ++ +P +F + L+   ++EK    L+V +  +       +V W R 
Sbjct: 6614 AGVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRG 6673

Query: 1053 GEIIKPKKNKYDF--EKRGHIRKLYIRNT-------SVHDEGEYSCILRDESCTAEVTVV 1103
             E + P +    F  EK G +    I  T       SV  + ++   + + +  + V   
Sbjct: 6674 IEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVD-- 6731

Query: 1104 ELPPEI-----ITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQL 1154
            E+P EI     +T L    V  G    FE    K D L    V+W ++G EI  +    +
Sbjct: 6732 EVPREILKAPTVTPLSAVVVPTGGTLFFE---AKYDGLPRPEVKWMRNGREIIENEETII 6788

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LV 1208
                    +K+ +      G+Y      +VG +K +  + V +   +  ++ P FI  L 
Sbjct: 6789 ETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLE 6848

Query: 1209 PA----NTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
            P     +  A +   +  E L    W+     I+ + +  ++S   K TL+I        
Sbjct: 6849 PKYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFV 6908

Query: 1264 CEYTCVL------LDAKSTTKL----KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
              +TC        + + +T  L    + E  E P  + +  +   +  G  + L      
Sbjct: 6909 GPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTG 6968

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
             P P  EW  N++ I + K T  S D +    L I +V   + G Y+    N  G +  +
Sbjct: 6969 KPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKIGKSVSK 7028

Query: 1373 MNVTI 1377
             NV I
Sbjct: 7029 TNVKI 7033



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 55/238 (23%), Positives = 92/238 (38%), Gaps = 21/238 (8%)

Query: 505  EQSMAPIFVEKLRPKHT-PDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561
            ++   P FV +++ + T  + +  +FECQ+   G P  ++ WF     +     FQ  YD
Sbjct: 3949 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 4008

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAG--------FASSTTELIVEAPLSDHGSEM-- 611
               VA +    V+PED+G + C A N  G          S    ++ ++ L  H   +  
Sbjct: 4009 FGYVA-MNFGWVYPEDSGEYVCRATNLYGKDETRAIIKVSGKPGIVYDSQLPAHMQSIDR 4067

Query: 612  --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
               +             D      P F  K + Q V+EG       R+   P P + WL 
Sbjct: 4068 IREMEASWQVVPDEVDPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLI 4127

Query: 670  KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
             G  +V      +  +   H     L +   +++  G   V+A N  GE+     LK+
Sbjct: 4128 NGHTVVHGSRYKLTNDGMFH-----LDVPKTRQYDTGKVEVIARNSVGESIATTELKV 4180



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568
           P+F +  +      G    FE ++ G P+P +TW R+ A +  SQ F+M Y++     +L
Sbjct: 87  PVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSL 146

Query: 569 VIREVFPEDAGTFTCVAKNAAGFA 592
           +I ++ P D G +TC A+N  G A
Sbjct: 147 LINQIGPGDEGEYTCTARNQYGEA 170



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 32/334 (9%)

Query: 504  EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQ--ITWFRQTAIIKPSQDFQMYY 560
            E Q   P++ + L+ + H  +   +  E  VE    P   I W+    ++     F+M  
Sbjct: 2886 ETQYPPPVWTKPLQAEFHLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMT- 2944

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTT------ELIVEAPLSDHGSEMTV 613
             +    T+ + EV+  D G +TC A N AG A +STT      E I+E+     G+E   
Sbjct: 2945 SEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTTIFCSSKENIIESTQHPKGAEGLE 3004

Query: 614  XXXXXXXXXXXXADILE----GIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD--IA 666
                            E    GIPP F+ +      + EG     E  L+ + +    I 
Sbjct: 3005 QIQDLEDSLRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIE 3064

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            W + G+ +     +       ++ + +V L++   K    GTYT  A N+ G A +   L
Sbjct: 3065 WFYNGKVLEASHRVRT-----IYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNL 3119

Query: 726  K-IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---AL 778
            + +     + P+    I+PL+ +   Q      +   V +P   + W  N K ++    +
Sbjct: 3120 ECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRI 3179

Query: 779  PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             T SD   + +  +   +  D G Y  +A N  G
Sbjct: 3180 KTVSDFG-YVVLDISYLQDHDSGEYVCRAWNKYG 3212



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 24/253 (9%)

Query: 481  TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVE--GYP 537
            T+ LQK L E + K    E  T +EQ   P F E+++     P+G  + F+C+VE  G P
Sbjct: 3650 TESLQK-LEETMHKRE--ELVTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDP 3706

Query: 538  RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
              +I WF    ++          D   +A L +  ++  D+G +TC A N  G A+++ +
Sbjct: 3707 TMRIEWFYNGHVMATGSRVHQLNDFGFIA-LDVDYIYARDSGEYTCRATNKWGTATTSAK 3765

Query: 598  --------LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYVDE 647
                    ++ E+ L + G                   ++E +  PP F+ +  +  VDE
Sbjct: 3766 VTCKGKHNIVYESQLPE-GMTSEKLKELERGRIPEAPKVVEEVFGPPKFTTQITSVTVDE 3824

Query: 648  GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
               +  EC++    +P   + W   G+ + P  +      +   M    L I  V     
Sbjct: 3825 AEAVRFECQVEPKTDPSLRVEWYRNGKPL-PSGH---RYRNIFDMGFVSLDILYVYGEDS 3880

Query: 706  GTYTVVAVNREGE 718
            G Y   A+N  GE
Sbjct: 3881 GEYVCRAINNYGE 3893



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 83/378 (21%), Positives = 146/378 (38%), Gaps = 40/378 (10%)

Query: 370  ELPKEDVPEQYTI-TPRKSSAQKIDE---IVDEVTIKKRLNP---FEIFYTPVEVRCGDT 422
            E+  +  P+Q  + T    S  K+ E   ++ E  ++ R +P    E F   + +  G  
Sbjct: 2611 EMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSR 2670

Query: 423  VFAVYSYVAETDEAINL-VEGERLYILDTSNQDWWYVQKHLT--EEKGWVPAQYLMDENN 479
            + + + +   T     L  +   +Y    +NQ    V       E++ W+ A+ L  ++ 
Sbjct: 2671 IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDRHWLQAESLHPDSL 2730

Query: 480  YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY--P 537
                   +L    +  P   +PT E     P+F+  L      +   V+FEC VE    P
Sbjct: 2731 PRI---GELEAPKEGRPEAPEPTYE----TPVFITHLNNIECKESDNVRFECNVEPARDP 2783

Query: 538  RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--- 594
               I WF     ++ +  F+  YD    A L +   + E++G +TC A N+ G A++   
Sbjct: 2784 TMSIEWFYNGQPLQAAAKFKSIYDFGYCA-LDLTNSYAENSGVYTCKATNSKGSATTSGT 2842

Query: 595  -------TTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
                   T  L  + P  + G E    T                 +  PP ++K  +A++
Sbjct: 2843 LKCTGGKTMFLDTQHPQGEAGLEAVQETEEELANRYTSKTTKPETQYPPPVWTKPLQAEF 2902

Query: 645  -VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
             + E   I LE  +    +P+  I W F G+ +       +  E         + +  V 
Sbjct: 2903 HLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMTSEFGF----VTMDMIEVY 2958

Query: 702  KFQEGTYTVVAVNREGEA 719
               +G YT  A N+ GEA
Sbjct: 2959 ARDQGIYTCKAYNKAGEA 2976



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 58/274 (21%), Positives = 106/274 (38%), Gaps = 23/274 (8%)

Query: 1464 ASETTE--YYKVIKETKIQSPT--VEKPLKNITTEP-----NEDIELTCIFGGVPQPKVT 1514
            A+ETTE  +   I+E  +Q P    + P+     +P     NE  +    F G P P V 
Sbjct: 4367 ATETTEVEHKGTIQERVVQGPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVK 4426

Query: 1515 WYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            WYR+   ++ +      T+  +               + C+A N  G  + S  + ++++
Sbjct: 4427 WYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEER 4486

Query: 1571 P------VITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
                   +   S     Q   V    L    A + G  P +V W KNG K++   ++ + 
Sbjct: 4487 RRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKML 4546

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
             ++    + I E     S +Y   A N AG +  +    +   PSKPE P          
Sbjct: 4547 EEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDGDC-IVQSPSKPEKPTTPGSEKAPH 4605

Query: 1683 VTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            +  + K   +++G   + +  ++       RW++
Sbjct: 4606 IVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMR 4639



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 4/127 (3%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            DE  Y    + KL        +  +P   E   AP  +  L+     +G   QF+  V G
Sbjct: 4670 DEGTYKCVAENKLGSIQTSAQLKVRPI--ENLDAPPTITALKDVSVTEGMPAQFKTTVTG 4727

Query: 536  YPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
              +   + WFR+  +I  + DFQM + D N A L+I   + ED+G FT    ++ G   S
Sbjct: 4728 KVKATSVQWFREGQLIPETPDFQMIF-DGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVES 4786

Query: 595  TTELIVE 601
            + +L V+
Sbjct: 4787 SAKLTVK 4793



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 63/246 (25%), Positives = 103/246 (41%), Gaps = 21/246 (8%)

Query: 490  EKIDKLPVFE---KPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQITW 543
            EKI +L  +    KP  EE+   PIF+  L   +H  +G     EC+VE    P  +I W
Sbjct: 2066 EKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPINDPNLKIEW 2125

Query: 544  FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--- 600
            F     +     ++  +D   VA L I  V+ ED GT+ C A N  G A +T  + V   
Sbjct: 2126 FCNGKQLPTGHRYRTTHDFGYVA-LDILYVYGEDTGTYICKATNQLGEAVNTCNVRVLNR 2184

Query: 601  EAPLSD--HGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK-AQYVDEGSDILLEC 655
             + + D  H   +               ++ +    PP F+ + + +  + EG     E 
Sbjct: 2185 RSMILDTQHPDALEKIQKLESKVPNARTEVGDAPISPPHFTAELRGSTEIYEGQTAHFEA 2244

Query: 656  RLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
            ++  + +P+  I +   G+ +       +  +     Y S L IT+      G Y+V AV
Sbjct: 2245 QVAPVHDPNLRIEFYHNGKPLPSASRFHITFDFG---YVS-LDITHAVAEDAGEYSVRAV 2300

Query: 714  NREGEA 719
            N  G+A
Sbjct: 2301 NALGQA 2306



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+FV KL P+   +G   +F  +V G+PRP++ W      +     +++   +D +  L 
Sbjct: 4092 PVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKL--TNDGMFHLD 4149

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
            + +    D G    +A+N+ G + +TTEL V A   D+
Sbjct: 4150 VPKTRQYDTGKVEVIARNSVGESIATTELKVVARSDDY 4187



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 15/193 (7%)

Query: 1091 LRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK-GDA--LVRWFKDGSEI 1146
            LR +    E   + +PP   T   N   + +G  A FE  L   GD   ++ WF +G  +
Sbjct: 3013 LRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIEWFYNGKVL 3072

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT-----VEEP---SINF 1198
            + S+ ++         L++    ++D G Y+C   N   TA ++     V++P      F
Sbjct: 3073 EASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVDKPRGQKPRF 3132

Query: 1199 TLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
            T  +     +     A+     + + D  L V WY    ++  + +   +SD     L I
Sbjct: 3133 TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDI 3192

Query: 1256 RKCTEDDQCEYTC 1268
                + D  EY C
Sbjct: 3193 SYLQDHDSGEYVC 3205



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 59/237 (24%), Positives = 90/237 (37%), Gaps = 23/237 (9%)

Query: 507  SMAPIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQ----ITWFRQTAIIKPSQDFQMYYD 561
            + AP F+  L+      +G    FE +VE  P+      I W+     I  +   Q YYD
Sbjct: 1021 TQAPRFLGPLKGTTKILEGQRAHFEARVE--PQSDLGLVIEWYHNGRSITAANRIQTYYD 1078

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM---------T 612
               VA L I +V  EDAG +  VA+N  G A     +IVE   S   S M          
Sbjct: 1079 FGYVA-LDISQVRAEDAGVYLVVARNKLGEAQQQATMIVETRSSIDTSSMHRGLYEKTQN 1137

Query: 613  VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFK 670
            +             +I +  P   +     + + +G +I LECRL  + +P   + W   
Sbjct: 1138 LENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHN 1197

Query: 671  GEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
            G  +          +    +   ++K T       G YTV A N  G A     +++
Sbjct: 1198 GRPVTVGSRFRTYYDFGF-VALDIIKATAA---DSGEYTVRATNHLGTAHTSACVRV 1250



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 8/175 (4%)

Query: 746  VRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDE 800
            + +GE     A +  VG+    I W  N K ++A   + T     T ++ +L  K ++D 
Sbjct: 3041 IGEGELAHFEANLIPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTK-IEDT 3099

Query: 801  GVYTLKAENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            G YT +A N  G AE S  +  V++P  +       I   + +   +    +       +
Sbjct: 3100 GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVND 3159

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            P   + WY N +++  S  I    D   + L I+ +    DSG+Y C A N  G+
Sbjct: 3160 PDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDH-DSGEYVCRAWNKYGE 3213



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 76/393 (19%), Positives = 145/393 (36%), Gaps = 32/393 (8%)

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
            R+         V+++  P P  +W   S  I+     +    S  + L I++V   D+ +
Sbjct: 4404 RVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAV 4463

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNI------LEIDSSSI---NICWDEPENTG 1408
            +    EN  G A    N+ ++++    GK  I        I S+++    +   + + TG
Sbjct: 4464 FSCVAENRGGTAKCSANL-VVEERRRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTG 4522

Query: 1409 NSTI-IYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDISDASE 1466
               + +Y++    +I  +    +       T  I       S R+   AVN    +    
Sbjct: 4523 TRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDG 4582

Query: 1467 TTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
                    K  K  +P  EK       LK+ T E    +   C   G P P   W R   
Sbjct: 4583 DCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGEN 4642

Query: 1521 KLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSC------VVGIQQK 1570
             +K ++    +R                   YKC+A N  G ++TS       +  +   
Sbjct: 4643 FVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVRPIENLDAP 4702

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P IT + +D+     +  ++  T V   +    V W++ G  +    ++ +     ++V+
Sbjct: 4703 PTIT-ALKDVSVTEGMPAQF-KTTVTGKVKATSVQWFREGQLIPETPDFQMIFDGNSAVL 4760

Query: 1631 RIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
             I       S  +T+  +++ G   SS ++T+K
Sbjct: 4761 LIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVK 4793



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQ 881
            E  E   E P+FI     I  KE   ++    V   R+P  SI W+ N + +  +     
Sbjct: 2745 EAPEPTYETPVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKS 2804

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +D     L +TN  +E +SG Y C A+NS G ++    +     K  F+
Sbjct: 2805 IYDFGYCALDLTNSYAE-NSGVYTCKATNSKGSATTSGTLKCTGGKTMFL 2853



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 10/176 (5%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D E+ E  +   +  +      +V W  +G  ++   +            L 
Sbjct: 372  PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 431

Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127
            I N +  D G   C+ R+++      A++ V+E    + P+ + R     V +G   T  
Sbjct: 432  ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 491

Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
               +      + W KDG +I  +    + IDG    L+I     +DAG Y C   N
Sbjct: 492  ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQN 547



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 11/228 (4%)

Query: 201   IDNEVPEKINVPDDKETSQTP------TSFNKRSKLTPIKIERKEM-EVSTPQHAETVDG 253
             I  E+P+ +  P  +   + P      +SF +  KLTP+KIE+ E  +    + +  V+ 
Sbjct: 11813 IHQEIPKTVLQPYQRTEMELPQRARRDSSFKQPVKLTPMKIEKVEFKKPKMVEISSVVEF 11872

Query: 254   PQFXXXXX-XXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGI 312
             PQ                + +       +LKS I+++  + P     +++ + + ++ G 
Sbjct: 11873 PQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIRFV-PYAPYCFPYVVTELETNREVGE 11931

Query: 313   LSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372
             LSRN+ EA +V K      K    EK ELE+      +   S K   E++  K    +  
Sbjct: 11932 LSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLGAYESDHSDKSNKELLHPKYKRGKKE 11991

Query: 373   KEDVP-EQYTITPRKSSAQKIDEIVDEVTIKK-RLNPFEIFYTPVEVR 418
             K + P E   +   K    + +E  +EV +K  +L+  EI    + VR
Sbjct: 11992 KIETPDESRKLKFGKGKVPQNEEASEEVNLKPVKLDIAEIEDAEMPVR 12039



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 62/270 (22%), Positives = 100/270 (37%), Gaps = 23/270 (8%)

Query: 499  EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
            ++P +      P+F + L+      +  T  FE ++   G P  ++ W+R   II+ S  
Sbjct: 2345 QEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSR 2404

Query: 556  FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615
                +D   V+ L I  +  ED G + C A N  G A +T  + V   +S+   +M    
Sbjct: 2405 ITKQHDFGFVS-LDISHIRKEDEGVYMCRAVNPLGEAVTTASMRV---VSEASIQMDTQH 2460

Query: 616  XXXXXXXXXXADILEGIPP----TFSKKPKAQYVD------EGSDILLECRLVAIPEPDI 665
                         L   P      F K    Q +       EG+    E R+V + +P +
Sbjct: 2461 PDSISRIHQLEKPLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSL 2520

Query: 666  --AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
               W   G E+     +   + +        L IT V     G Y   A N  GEA    
Sbjct: 2521 KFEWFINGVEL----QMGSRLRTTHDFGFVTLDITAVVPEDAGVYMCRAYNAAGEAVSST 2576

Query: 724  VLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             +K+KT      Q + P     +R  E+ +
Sbjct: 2577 AMKVKTKSNIDGQPLIPESWEAIRLKEAAM 2606



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNNEIISPSETITQNFD 884
            EE   PP F  +   +TV E   ++   +V     PS  + WYRN + +         FD
Sbjct: 3805 EEVFGPPKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFD 3864

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
               + L I  V  E DSG+Y C A N+ G+     R T+  +K+
Sbjct: 3865 MGFVSLDILYVYGE-DSGEYVCRAINNYGEDR--TRATVSCKKL 3905



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 31/117 (26%), Positives = 61/117 (52%), Gaps = 9/117 (7%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
           PPQ I PL+++   +G  V + A++  VG+P   + W  N +P+ A    +         
Sbjct: 617 PPQFIIPLQNVQQTEGGRVHMEARIEPVGDPTMVVEWYLNGRPLAASARATSVFKFGFIA 676

Query: 792 LKPKKVK--DEGVYTLKAENSEGIAETSAVIT-VEEPT-EENAEPP---LFINRFQE 841
           L    +   D G Y  +  N+ G+AE+ A+++ V+ P+ E++++ P    +IN+ ++
Sbjct: 677 LDLLSIMGHDSGEYMCRVTNASGVAESRAILSVVQRPSIEQSSQNPNSLQYINQLED 733



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 5/105 (4%)

Query: 815  ETSAVITVEEP-TEENAEPPLFINRFQEIT-VKEKGTIKLVARV--TRNPVPSITWYRNN 870
            E++A    +EP T    + P+F    Q I  + E  T    AR+    +P   + WYRN 
Sbjct: 2337 ESTAPHQRQEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNE 2396

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            +II  S  IT+  D   + L I+++  E D G Y C A N  G++
Sbjct: 2397 KIIEDSSRITKQHDFGFVSLDISHIRKE-DEGVYMCRAVNPLGEA 2440



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 37/157 (23%), Positives = 67/157 (42%), Gaps = 13/157 (8%)

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            + +  ++  + W  +G++++           G +  L +  T + D G Y+C   ++  T
Sbjct: 3054 IPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVA-LEVLGTKIEDTGTYTCRATNKHGT 3112

Query: 1098 AEVTV----VELP----PEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSE 1145
            AE++     V+ P    P   + +Q  + +  G  A FE   I +   D  V W+ +G  
Sbjct: 3113 AEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 3172

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            ++ SN I+   D     L I      D+GEY C   N
Sbjct: 3173 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWN 3209



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 827  EENAEPPLFINRFQE-ITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNF 883
            +E   PP F    ++ + V E G I    RV    +P   I W+ N  +++    + Q  
Sbjct: 3670 DEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVHQLN 3729

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            D   I L +  + +  DSG+Y C A+N  G ++  A+VT
Sbjct: 3730 DFGFIALDVDYIYAR-DSGEYTCRATNKWGTATTSAKVT 3767



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 17/212 (8%)

Query: 44    LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVK----LPKFQLKSRIK 99
             L  ++IE++E  KP+  E  +V +F             QE    K        +LKS I+
Sbjct: 11848 LTPMKIEKVEFKKPKMVEISSVVEFPQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIR 11907

Query: 100   FIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLF 159
             F+  + P     +VT L + ++ GELSRNV EA                E+  LE++DL 
Sbjct: 11908 FV-PYAPYCFPYVVTELETNREVGELSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLG 11966

Query: 160   DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
               + D S  D S        +    PK     ++ I    E       K  VP ++E S+
Sbjct: 11967 AYESDHS--DKS-------NKELLHPKYKRGKKEKIETPDESRKLKFGKGKVPQNEEASE 12017

Query: 220   TPTSFNKRSKLTPIKIERKEMEVSTPQHAETV 251
                   K  KL   +IE  EM V T Q  E V
Sbjct: 12018 EVNL--KPVKLDIAEIEDAEMPVRT-QEEEVV 12046



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 5/103 (4%)

Query: 825 PTEENA--EPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880
           P EE+    PP FI   Q +   E G + + AR+    +P   + WY N   ++ S   T
Sbjct: 608 PGEEDRVYPPPQFIIPLQNVQQTEGGRVHMEARIEPVGDPTMVVEWYLNGRPLAASARAT 667

Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             F    I L + ++    DSG+Y C  +N++G +   A +++
Sbjct: 668 SVFKFGFIALDLLSIMGH-DSGEYMCRVTNASGVAESRAILSV 709



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F +  K     +G + L E RL   P+P + W  KG  ++  +   ++  ++     
Sbjct: 86  PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSY-NEATGDV 144

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
           S+L I  +    EG YT  A N+ GEA   + ++ +       Q I+ L+  I   G S
Sbjct: 145 SLL-INQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPIQNLEKNIYSNGYS 202



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 21/78 (26%), Positives = 35/78 (44%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
            IS +    K   G + + TA +   P P + W+ NG +L   ++Y I+     + +R+K 
Sbjct: 257  ISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRVKN 316

Query: 1635 LKRSHSSKYTIEASNTAG 1652
                    YT+ A N  G
Sbjct: 317  ATARDGGHYTLLAENLQG 334



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 6/120 (5%)

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880
            EE  E   + P+F    + + +KE        R+    +P   + WY NN  +      T
Sbjct: 1548 EEIDESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFT 1607

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
            +  +   + L I +   E D+G Y C A N+ G++   A   +  +K  +   L+  +ET
Sbjct: 1608 ETNNFGFVALDIMSTLPE-DAGTYTCRAYNAVGEAITSAVAVVHTKKSIY---LESQHET 1663



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 14/160 (8%)

Query: 1461 ISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWY 1516
            I    +T+ + +   E +  +  P   +PL+N        + L  T I    P  KV WY
Sbjct: 1935 IQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWY 1994

Query: 1517 RDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             +G+ ++T    K TY+                  Y C A N  GE  T+C V +     
Sbjct: 1995 CNGRPIQTGHRFKTTYDFGFVALDILYAHAEDTGTYMCKAKNAIGEAVTTCAVNVTANKT 2054

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            + +   D ++  K+    L T      PPP+ +  + G K
Sbjct: 2055 LDLDTLDAQRLEKI--RQLETYA----PPPKPVVEEKGQK 2088



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 59/249 (23%), Positives = 103/249 (41%), Gaps = 22/249 (8%)

Query: 164   DESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK-ETSQTPT 222
             +ES  D   P   ++ EA  E    + SE+P  K  E++ E  EK    DDK ET++   
Sbjct: 13747 EESIIDEPIPEDYVVTEAAEE----KPSEEPTFKVEELETEAVEKEVTDDDKGETTKQSV 13802

Query: 223   SFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQL 282
             +  K  KL   K E  E+ V T    +T D P++              E      P+ + 
Sbjct: 13803 TKRKIKKLVGPKEEIIEI-VET----KTGDTPEYEVIVTTEEVQEKSKEA-----PEEKK 13852

Query: 283   KSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL- 341
                ++     P + ++    Y+  + +  I    +++  K+     V  K   ++K +  
Sbjct: 13853 AKTVRKAKKIPKDDLQ---DYIQKLIEQDIPKTELEKYEKIDLDEPVKMKRKPIKKVKQS 13909

Query: 342   -EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVT 400
              EQP    E+ +E K  E +I +  +   + PK  V  +  I P K   +  + +V E T
Sbjct: 13910 EEQPKEETEEPIEDKPVE-KISEYSEVDSDEPKLTVAVKEFI-PEKPEEKPFEIVVLEET 13967

Query: 401   IKKRLNPFE 409
             ++ +  P E
Sbjct: 13968 VESKREPDE 13976



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIE 889
           PP+F   F+     + G      R+  NP P +TW R    +  S+    +++    ++ 
Sbjct: 86  PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVS 145

Query: 890 LVITNVDSEIDSGDYKCVASNSAGKS 915
           L+I  +    D G+Y C A N  G++
Sbjct: 146 LLINQIGPG-DEGEYTCTARNQYGEA 170



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 8/115 (6%)

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFG--GVPQPKVTWYRDGKKLKTA---KATYE- 1530
            T +Q+P   + L NI T    ++ L C     G P  ++ W+ +GK +KT    +  YE 
Sbjct: 1286 TIMQAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEF 1345

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQK 1583
            +                Y C A N  GE  TSC V I  K   ++   NE   QK
Sbjct: 1346 DYVALDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQK 1400



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGD 785
           G+  PP   +  K+    QG + +   ++ GNP+P +TW +   P+    K   + ++  
Sbjct: 82  GDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEAT 141

Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------EPTEENAEPPLFINR 838
                ++      DEG YT  A N  G A  S  I  E       +P  +N E  ++ N 
Sbjct: 142 GDVSLLINQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPI-QNLEKNIYSNG 200

Query: 839 FQEITVKEK 847
           +   +++E+
Sbjct: 201 YSYTSIEEE 209



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYNITTKE 1625
            QQ PV T   +   + H+ G   L+ A +E    P   + W+KNG  L        T   
Sbjct: 2619 QQAPVFTTHLQSYDKLHE-GQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDF 2677

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
                + I  L+   S+ YT +A+N  G +    +LK+ D+
Sbjct: 2678 GLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDR 2717



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 18/90 (20%), Positives = 42/90 (46%)

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            ++ ++  +  P +++  R+ R   G      + +   P P+ +W  N+  ++  +  +  
Sbjct: 7179 QVALKAAKCSPSLLNEMRDCRAALGETAKFSIQFAGNPIPDIQWYFNNVQLRASEKYRMV 7238

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            +  + A+L I K+ + D G Y  +L N  G
Sbjct: 7239 VQEQEATLEIMKITSEDCGYYNCKLINEIG 7268



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 64/298 (21%), Positives = 114/298 (38%), Gaps = 39/298 (13%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P+I  + ++ K+ +G+ A F   + +     + WF +G  +  S   +++       L++
Sbjct: 255  PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRV 314

Query: 1166 YDCDLDDAGEYSCEVGNSK-C---TAILTVE-------EPS-INFTLRLPEF--ILVPAN 1211
             +    D G Y+    N + C   +A+L VE       EP  ++      E    L PA 
Sbjct: 315  KNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPPAF 374

Query: 1212 TDAYLTVEIPDETL-------------DVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRK 1257
              A+   EI +  +             +V W    + V +D     L+++    +L+I  
Sbjct: 375  VKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITN 434

Query: 1258 CTEDDQCEYTC--------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             T  D     C        V ++A+     K +VV   P+ V       ++ G  +T+  
Sbjct: 435  VTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVA--PQFVQRFSTMTVREGEPITMSA 492

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            +    PQP   W  +   I         ID  +  L I +V   DAG Y+   +N  G
Sbjct: 493  NAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAG 550



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 732  KEPPQVIEPLKS-MIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGD 785
            K  P  + PL     +  G+++ L  ++  +G+P   + W  N +PV       T  D  
Sbjct: 1155 KSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSRFRTYYDFG 1214

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
              ++ I+K     D G YT++A N  G A TSA + V + T+
Sbjct: 1215 FVALDIIKATAA-DSGEYTVRATNHLGTAHTSACVRVIDHTD 1255



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 7/124 (5%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP--KVTWYRD 1518
            + D S  T   ++ + TK Q+P     LKN+  + N+     C    V  P  +V WY +
Sbjct: 1538 LEDRSRYTRREEIDESTK-QAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHN 1596

Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
               LK+     E                     Y C A+N  GE  TS V  +  K  I 
Sbjct: 1597 NLPLKSGSRFTETNNFGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIY 1656

Query: 1575 ISNE 1578
            + ++
Sbjct: 1657 LESQ 1660



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            ++ P+F    +++ V E   +   AR+    +P  ++ W RN + I  S   T   D   
Sbjct: 1688 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 1747

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + L +  V+ E DSG Y C A N  G++   A + +
Sbjct: 1748 VALNMKYVNPE-DSGTYTCRAVNELGQAVTSASLIV 1782



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
            I+ + DF     D++ L+   + E     W + GE     +   +   RG +    ++  
Sbjct: 3179 IKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYGEDFT--RTTLNCGGRGGVFYDSLQPD 3236

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK---GDA 1135
            S+    E  C    ++ T+   V E PP+ IT++ +  K+ +G  A FE  LT     D 
Sbjct: 3237 SLQRIRELECPQGQQADTSAPLVAE-PPKFITQIVDVTKLVEGQSAHFEARLTPITDPDL 3295

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +V W+ +G ++   +  +   D     L I  C  +++G Y     N
Sbjct: 3296 VVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARN 3342



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 36/196 (18%), Positives = 77/196 (39%), Gaps = 10/196 (5%)

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            C   G P P+V W  +G++++   +                          +C+A N  G
Sbjct: 393  CRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITNVTRLDAGAVQCLARNKAG 452

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            EV     + + +K  + ++ + +++   +    G+   ++A   G P P + W K+G ++
Sbjct: 453  EVAIEAQLNVLEKEQV-VAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQI 511

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
             +  E  +      + + I  +  + +  Y   A N AG+++    L V     +P    
Sbjct: 512  SSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQ 571

Query: 1674 IMREISRESVTIEWKP 1689
                + R +  IE +P
Sbjct: 572  RRLNLPRPTKVIEPEP 587



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            +P  +    P+F+++ +  TV+E    +   RVT +P P + W  N   +          
Sbjct: 4083 DPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKLTN 4142

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            DG    L +     + D+G  + +A NS G+S
Sbjct: 4143 DG-MFHLDVPKT-RQYDTGKVEVIARNSVGES 4172



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 4/102 (3%)

Query: 504 EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYY 560
           E+ + AP F+  LR      +G  V FE QV     P  ++ W++    I  S      +
Sbjct: 745 EQLNQAPQFIRPLRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIF 804

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
           +   V+ L I  +  EDAGT+T  A N  G A S + + V +
Sbjct: 805 NFGYVS-LNILHLRAEDAGTYTVRAVNRIGEAISQSSIRVHS 845



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
            E PQ   PL++  V +G  V L A +  V +P   + W  N +P++      T  D    
Sbjct: 1956 ERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFV 2015

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++ IL     +D G Y  KA+N+ G A T+  + V
Sbjct: 2016 ALDILYAH-AEDTGTYMCKAKNAIGEAVTTCAVNV 2049



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 1106 PPEIITRLQNQ-KVNKGNKATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161
            PP+  T +QNQ  + +   A FE  L   GD+ +R  W KDG  ++ S+ I    +    
Sbjct: 889  PPQFKTPIQNQLDLREHAHAHFEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYV 948

Query: 1162 KLKIYDCDLDDAGEYSCEVGNS 1183
             L I    + DAG Y+C   N+
Sbjct: 949  ALTIKQLTIYDAGTYTCRAYNA 970



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNN 870
            + +TS      +  + +AE P F    +   V E   + L A +    +P   + WY N 
Sbjct: 1938 LEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNG 1997

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
              I         +D   + L I    +E D+G Y C A N+ G++     V +   K
Sbjct: 1998 RPIQTGHRFKTTYDFGFVALDILYAHAE-DTGTYMCKAKNAIGEAVTTCAVNVTANK 2053



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 6/130 (4%)

Query: 815  ETSAVITVEEPTEEN-AEPPLFINRFQEI-TVKEKGTIKLVARVTR--NPVPSITWYRNN 870
            E S V T EE TEE   + P+F    + I  ++E       AR+T   +P   + WY N 
Sbjct: 3382 EYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYWNG 3441

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VT 929
              +          D   + L I+ V  E DSG+Y C A N  G++   A + I  ++ + 
Sbjct: 3442 RPLKAGSRFRTFCDFGFVILEISPVYPE-DSGEYSCRAINEYGEAVTTATMKIQGKRSII 3500

Query: 930  FVKHLQKSYE 939
                L K  E
Sbjct: 3501 MESQLPKGME 3510



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 18/198 (9%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            PP  I  L+ +   +   A  E  + + + L   +WF     I+ SN +++     K  L
Sbjct: 6840 PPRFIQPLEPKYFGEHEVAIIEA-IVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTL 6898

Query: 1164 KIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINF-TLRLPEFILVPANT---- 1212
             I +      G ++C   N      S  T  L  +E +  F + R  E ++ P       
Sbjct: 6899 LIENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGE 6958

Query: 1213 DAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVL 1270
               LT ++  + T  V WY     I + ++ T+  D++    L I +   +++ +Y CV 
Sbjct: 6959 ALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVA 7018

Query: 1271 LD--AKSTTKLKVEVVEF 1286
             +   KS +K  V++  F
Sbjct: 7019 TNKIGKSVSKTNVKIQAF 7036



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 7/105 (6%)

Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDT 786
           + PQ I PL+ +    +G++V   AQV  V +P   + W K+  P+ A   +    +   
Sbjct: 749 QAPQFIRPLRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIFNFGY 808

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            S+ IL   + +D G YT++A N  G A + + I V   ++  A+
Sbjct: 809 VSLNILH-LRAEDAGTYTVRAVNRIGEAISQSSIRVHSRSQVTAD 852



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
            + PQ    L ++   +G +V L    Q VG+P   I W  N KPVK         + D  
Sbjct: 1289 QAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYV 1348

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++ +L    + D GVYT +A N  G A TS  + +
Sbjct: 1349 ALDLLGCYAI-DSGVYTCQARNQLGEAVTSCSVRI 1382



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 11/128 (8%)

Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD---ALVRWFK 1141
            EYS +   E  T E       P     L+N + + +G  A FE  +T  D     V W+ 
Sbjct: 3382 EYSMVRTREETTEETK--GKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYW 3439

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI 1196
            +G  ++  +  +   D     L+I     +D+GEYSC    E G +  TA + ++ + SI
Sbjct: 3440 NGRPLKAGSRFRTFCDFGFVILEISPVYPEDSGEYSCRAINEYGEAVTTATMKIQGKRSI 3499

Query: 1197 NFTLRLPE 1204
                +LP+
Sbjct: 3500 IMESQLPK 3507



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 27/257 (10%)

Query: 159   FDSQEDESKPDVSQPPQN--IIEEAKSE---PKLIEESEQP-IAKTSEIDNEVPEKINVP 212
             F +++ E KP V + P+    I++ K +   P+++EE E   + K      EV E+  + 
Sbjct: 15786 FATKDSEKKPTVEELPEEQVTIQKKKKKAPVPEVVEEPEAEFLVKPKTPVQEVTEEAKIT 15845

Query: 213   DDKE-TSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271
               K+   +   +   +  +T       E++    +  E  +                  E
Sbjct: 15846 KSKKPVKEEEAAAELKVTITEEIPTEPEVQEIIEEIEEIEEEKPAEYVIEVKESQPEAVE 15905

Query: 272   TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331
                V LPK + K+ I        E  +  I+    +K     S  ++E AK+ K+   P 
Sbjct: 15906 DKEVSLPKKKPKAPIV-------EEPEAEITLKPKVK-----SEEVQEEAKIVKKK--PK 15951

Query: 332   KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYT----ITPRKS 387
             K+ +V   + E  +   E++V     E E+I+E + +++ PKE  PE       +  +K 
Sbjct: 15952 KIDEVAVAD-ELTVKVEEEVVPEPIVEEEVIEEFE-IKKKPKEPEPEDIVDAAIVKLKKP 16009

Query: 388   SAQKIDEIVDEVTIKKR 404
                  DE+V EVT+K +
Sbjct: 16010 EPVDADEVVAEVTLKPK 16026



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 5/114 (4%)

Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALV 1137
            +H   ++S   R E    E TV   P  +   +    + +G  A +E  +      +  V
Sbjct: 1801 IHQLEDHSRYQRREE--EEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKV 1858

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
             WF +G  +   +  + T D     L I     +D+GEY+C V N+   AI ++
Sbjct: 1859 EWFHNGKPLSTGHRFRTTYDFGFAALDILTVYAEDSGEYTCRVTNNLGEAINSI 1912



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%)

Query: 804  TLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEIT-VKEKGTIKLVARVT--RN 859
            TL A+  E I +        +P  EE  + P+F+     +  +KE     L  RV    +
Sbjct: 2059 TLDAQRLEKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPIND 2118

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P   I W+ N + +          D   + L I  V  E D+G Y C A+N  G++ +  
Sbjct: 2119 PNLKIEWFCNGKQLPTGHRYRTTHDFGYVALDILYVYGE-DTGTYICKATNQLGEAVNTC 2177

Query: 920  RVTI 923
             V +
Sbjct: 2178 NVRV 2181



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 1107 PEIITRLQNQKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            P+    L+N KVN+G     E   I +      V W+ +G  IQ  +  + T D     L
Sbjct: 1958 PQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFVAL 2017

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILT 1190
             I     +D G Y C+  N+   A+ T
Sbjct: 2018 DILYAHAEDTGTYMCKAKNAIGEAVTT 2044



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 9/121 (7%)

Query: 730  GEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKSD 783
            G ++ P   +PL+++  + + ++    A++  VG+P   + W +N K ++    +  + D
Sbjct: 2351 GTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHD 2410

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQE 841
                S+ I   +K +DEGVY  +A N  G A T+A + V  E   + + + P  I+R  +
Sbjct: 2411 FGFVSLDISHIRK-EDEGVYMCRAVNPLGEAVTTASMRVVSEASIQMDTQHPDSISRIHQ 2469

Query: 842  I 842
            +
Sbjct: 2470 L 2470



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 64/274 (23%), Positives = 108/274 (39%), Gaps = 20/274 (7%)

Query: 162  QEDESKPDVSQPPQNIIEEAKS---EPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218
            +ED  KP V   PQ ++ E K    +P+ + E +  +A T   +  V    + P  +E  
Sbjct: 5562 EEDLIKP-VQPEPQPVLWERKKKKPQPQDVIEEKLDVAPTKTYEKAVDVLPDEPKVEEKP 5620

Query: 219  QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278
            + P  + +  K  P K E  E EV    H + VD                       K P
Sbjct: 5621 E-PVLWQRGKKKIP-KSEPTE-EV----HPDEVDAQIETVVKEDEMIVEEKRRIKKTKRP 5673

Query: 279  KFQLKSRIKYITSWPPESIKP-----LISYMGSIKQNGILSRNIKEAAKVK-KQVFVPPK 332
            K   +   +     P E I P         +  I++     R +K+  K K  Q     +
Sbjct: 5674 KSTKEVTEELFEEQPEEEISPEEEVPQKEVIEEIEEIVEEKRRLKKTKKPKLTQQVTEEE 5733

Query: 333  LPDVEKT-ELEQPLFSYEDIVESKKDENEIIQEKQTLE-ELPKEDVPEQYTITPRKSSAQ 390
             P  E   E E+ +   E+IVE KK   ++ + K   E +L +E++P + T+   +++  
Sbjct: 5734 TPHEEIIKESEEVVQEQEEIVEEKKKVKKVKKPKTVAEKQLKEEEIPTEETVEEEETAED 5793

Query: 391  KIDEIVDEVTIKKRLNPF-EIFYTPVEVRCGDTV 423
            +   + +   +KK   P   +  T VE   G+ V
Sbjct: 5794 QQLVVEESKKVKKVKKPTGTVEKTDVEELPGEEV 5827



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 78/399 (19%), Positives = 160/399 (40%), Gaps = 40/399 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
            P    KL+  +   ++  +LE ++       +     +I+     KY+      + KL I
Sbjct: 6536 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 6595

Query: 1077 RNTSVHDEGEYSCILRDES--CTAEVTVV-----ELPPEIITRLQ----NQKVNKGNKAT 1125
               +  D G Y+C  ++E+   T+   ++      +PP+    L+     +K  +  K T
Sbjct: 6596 AKVTPSDVGVYTCEAKNEAGVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVT 6655

Query: 1126 FEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGN 1182
               ++T K +  V+W++   E+  S  +Q+  D K     L++ +   ++A  YS +  N
Sbjct: 6656 VTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQN 6715

Query: 1183 SKCTA-----ILTVEEPSINFTLRLP-----EFILVPANTDAYLTVEIPD-ETLDVTWYK 1231
                A     IL+  +      L+ P       ++VP     +   +       +V W +
Sbjct: 6716 QFGRAIGNANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMR 6775

Query: 1232 K-KSVIEDTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLDAKSTTKLKV---- 1281
              + +IE+ E  T+I   +  T I      RK T   +      + +AKS+  + V    
Sbjct: 6776 NGREIIENEE--TIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQK 6833

Query: 1282 --EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
              E ++ P  I   E +Y  +    +   +  ++ P  + +W V+++ IK     +    
Sbjct: 6834 PDEQIKPPRFIQPLEPKYFGEHEVAIIEAI-VESEPLSSFQWFVHNEPIKSSNEVRIVSQ 6892

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
            +  ++L I+  ++   G +  R EN  G       V ++
Sbjct: 6893 ANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATVNLI 6931



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)

Query: 529 FECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
           FE ++E  G    ++ W +    ++ S     Y++   VA L I+++   DAGT+TC A 
Sbjct: 910 FEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYVA-LTIKQLTIYDAGTYTCRAY 968

Query: 587 NAAGFASSTTELIV 600
           NA G  ++  +L V
Sbjct: 969 NAMGQDTTVAQLTV 982



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 41/185 (22%), Positives = 77/185 (41%), Gaps = 15/185 (8%)

Query: 1102 VVELPPEIITRLQN-QKVNKGNKATFEIEL---TKGDALVRWFKDGSEIQFSNHIQLTID 1157
            VV + P  +T  ++     +G  A FE ++   T  +  V WFK+G  I   +  +   D
Sbjct: 1419 VVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHD 1478

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
                 L I     +D+G Y+C   N     ++  +E  +    R  E I+     +A L 
Sbjct: 1479 FGYVALDIVHLIAEDSGVYTCRAVN-----LIGSDETQVELQCRSGEQIVTVTQNEAGL- 1532

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             E      D + Y ++  I+++ K   +     + + I+   E+ +  + C L+   S  
Sbjct: 1533 -EQIHYLEDRSRYTRREEIDESTKQAPVFTTSLKNVEIK---ENQRAHFECRLIPV-SDP 1587

Query: 1278 KLKVE 1282
             ++VE
Sbjct: 1588 SMRVE 1592



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 1107 PEIITRLQN-QKVNKGNKATFEIELT-KGDALVR--WFKDGSEIQFSNHIQLTIDGKKQK 1162
            P   T LQ+  K+++G     E ++  + D  +R  WFK+G  +   + I+ T D     
Sbjct: 2622 PVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDFGLVT 2681

Query: 1163 LKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193
            L I     DD+  Y+C    +VG +  T+ L +E+
Sbjct: 2682 LSINGLRADDSAIYTCKATNQVGEAVSTSSLKIED 2716



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 16/62 (25%), Positives = 28/62 (45%)

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            EW  N K+++     +      + +L +   +  D G Y  R  N  G A++  N+  +D
Sbjct: 3064 EWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVD 3123

Query: 1380 KP 1381
            KP
Sbjct: 3124 KP 3125


>UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora|Rep:
             Isoform B of Q9I7U4 - Drosophila melanogaster (Fruit fly)
          Length = 17903

 Score =  830 bits (2053), Expect = 0.0
 Identities = 392/769 (50%), Positives = 526/769 (68%), Gaps = 6/769 (0%)

Query: 584   VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
             VAKNAAGF SSTTELIVE+PLSDHGS+ T             ADILEGIPPTFSKKPKAQ
Sbjct: 16007 VAKNAAGFTSSTTELIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQ 16066

Query: 644   YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIESDMHMYCSVLKITNVK 701
             YVDE ++++LECRLVA+PEPDI W F GE+I  +E  N+ +  ESDMHMYCSV+ I+ VK
Sbjct: 16067 YVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVK 16126

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
             K QEGTY V+A NREGEA LPI LK++T +KE PQ++EPL++M++R+GESV+LS Q+VGN
Sbjct: 16127 KSQEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGN 16186

Query: 762   PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             P P +TW K+ KPVK    KSD D H++T++ P+K  ++G YT+KA N  G  ET+A +T
Sbjct: 16187 PPPKVTWYKDGKPVKN--AKSDKDLHTLTLITPQK-SEKGEYTVKAVNPLGSVETTANLT 16243

Query: 822   VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
             +EEP   NAEPPLF+ RF+E  V +KG I+L A+V+ NPVP + W  NN  + PSE I Q
Sbjct: 16244 IEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQ 16303

Query: 882   NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
              +DGENIEL+I + + E DSGDYKC+ASN  GK+SHGARV ++V++VTF K L+K+   E
Sbjct: 16304 VYDGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTFTKKLKKTITIE 16363

Query: 942   EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             E +++ LEC+TSH V+TKW+ N KE+SGMDHR ++++G+            D G   C V
Sbjct: 16364 EVQSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKV 16423

Query: 1002  KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
             K QET + + V +  P+FI+ L+D+EV EKD AIL+VE+ +E  +V W +DGE I P+  
Sbjct: 16424 KKQETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTEATEVTWYKDGEKITPENK 16483

Query: 1062  KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
               +F K G  R+L IR+ ++HDEG+Y+C +  + C+ E+ V+ELPPEI+  L +  V KG
Sbjct: 16484 NVEFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVVIELPPEIVEPLNDVAVTKG 16543

Query: 1122  NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
               A FE+EL+KGDALV+WFK+G EI F+  IQL IDGKKQ L+I     +D GEYS +VG
Sbjct: 16544 ENAVFEVELSKGDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVG 16603

Query: 1182  NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
                  A LTVEEP ++F +RLP+  L    TDA  TV++    ++VTW KK   I+  +K
Sbjct: 16604 EQTSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQK 16663

Query: 1242  FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIK 1300
               +  +   R L+I   +++D  E +CV  +  S+TKL VE ++ PP I  D ++  ++K
Sbjct: 16664 HEVFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVK 16723

Query: 1301  RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
                DVT  V Y   P P   W     +I K K T P+ID +SA LTIKK
Sbjct: 16724 ENDDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKK 16772



 Score =  176 bits (429), Expect = 5e-42
 Identities = 91/279 (32%), Positives = 152/279 (54%), Gaps = 10/279 (3%)

Query: 1433  ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---- 1488
             IT  +     +K N    F       V   +A  TT    VI ++K   PT+++      
Sbjct: 16712 ITSDKDQTIKVKENDDVTFTVKYTG-VPTPEACWTTRKV-VIPKSKRTIPTIDEQSAKLT 16769

Query: 1489  --KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX- 1545
               K++ +E ++++ L+C+FGG+P+PKVTW ++G+  ++    YENR              
Sbjct: 16770 IKKDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYTIEKTTIETE 16829

Query: 1546  XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
               Y C+A N+ G  ETSC + +QQKPV+ + ++ + QK + G    + A + G P P V 
Sbjct: 16830 ATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVT 16889

Query: 1606  WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
             W+K   + +  K   I T E TS   +K++ R  S KY + A+N +GT+ VE T++V DK
Sbjct: 16890 WHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDK 16949

Query: 1666  PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             PS+P+  + +++I ++S+ +EW PP+DDG  +  K + E
Sbjct: 16950 PSRPQS-LEIKDIKKDSIVLEWTPPVDDGDEDEVKRSAE 16987



 Score =  164 bits (399), Expect = 2e-38
 Identities = 170/701 (24%), Positives = 299/701 (42%), Gaps = 69/701 (9%)

Query: 494   KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
             +LP+  K  + ++  AP  +E LR     +G +V    Q+ G P P++TW++    +K +
Sbjct: 16145 RLPITLKVRTTDKE-APQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNA 16203

Query: 554   QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
             +       D ++ TL +      + G +T  A N  G   +T  L +E P   +      
Sbjct: 16204 K------SDKDLHTLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAE---- 16253

Query: 614   XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                                PP F ++ + Q V +  +I L  ++   P P++ WLF    
Sbjct: 16254 -------------------PPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTP 16294

Query: 674   IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
             + P E I    + +      ++K  N  +   G Y  +A N  G+ S    + ++  E  
Sbjct: 16295 LFPSERIQQVYDGENIEL--IIKDAN-PETDSGDYKCIASNPIGKTSHGARVIVEVDEVT 16351

Query: 734   PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
               + ++  K++ + + +S+ L  +   +   T  W  N K +  +  +    DG TH + 
Sbjct: 16352 FTKKLK--KTITIEEVQSLTLECET--SHVVTTKWFFNGKELSGMDHRVVVEDGKTHKL- 16406

Query: 791   ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
             +++   ++D G YT K +      ET + + V +        P FI   ++  V EK T 
Sbjct: 16407 VIRNTNLRDSGTYTCKVKKQ----ETQSTVEVLQ------RKPDFIKVLEDYEVTEKDTA 16456

Query: 851   KLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              L   +T      +TWY++ E I+P ++ +    DG+   LVI +V    D G Y C   
Sbjct: 16457 ILDVELT-TEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIH-DEGQYTC--- 16511

Query: 910   NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEIS 968
                G+      V I++     V+ L     T +G+  + E + S      KW+ N KEI 
Sbjct: 16512 KIEGQECSCELVVIELPP-EIVEPLNDVAVT-KGENAVFEVELSKGDALVKWFKNGKEIV 16569

Query: 969   GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028
               +  ++  +G+            DVG     V +Q +   L V+E + +F+ +L D  +
Sbjct: 16570 FNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVGEQTSKAKLTVEEPLVDFVIRLPDITL 16629

Query: 1029  KEKDV-AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
               K   A   V+++    +V W + G+ IKP + K++    G +R+L I + S  D GE 
Sbjct: 16630 ATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQ-KHEVFVEGTVRRLVIHDASDEDAGEI 16688

Query: 1088  SCILRDESCTAEVTVVELP-PEIITRLQNQ--KVNKGNKATFEIELT-KGDALVRWFKDG 1143
             SC+  + + + ++ V EL  P +IT  ++Q  KV + +  TF ++ T        W    
Sbjct: 16689 SCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWTTRK 16748

Query: 1144  SEIQFSNHIQLTIDGKKQKLKIYD---CDLDDAGEYSCEVG 1181
               I  S     TID +  KL I      +LD     SC  G
Sbjct: 16749 VVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFG 16789



 Score =  153 bits (372), Expect = 4e-35
 Identities = 137/536 (25%), Positives = 230/536 (42%), Gaps = 69/536 (12%)

Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
           Q L D+ +  + + + + + I    +F    +E +  +P+F   L+   + +G    FEC
Sbjct: 191 QTLRDQVDQQRIVTENIRKDIQVNSIF----TELRYASPLFTRPLKDAVSREGDRFVFEC 246

Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
           +V G P P + WF+    I+ + D++  +D   +  LVI E F  D+  F+C A N  G 
Sbjct: 247 EVTGTPEPAVEWFKDGISIQTNSDYKTTFDK-GICRLVIEETFAADSARFSCRASNLVGT 305

Query: 592 ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
             +   L V     ++ +E+ +                  +PP   +  ++    EGS  
Sbjct: 306 CDTNATLSVR----ENAAEVQL------------------VPPRILRFLQSGKATEGSSF 343

Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
              C +  +P P + W FK ++ + D    V   ++     + LK   V    +  YT  
Sbjct: 344 QFACVVAGVPLPTVQW-FKNDKCIDDSPDYVISYNNGE---ATLKFEEVFLEDDAVYTCS 399

Query: 712 AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
           A N  G       L ++  E  E P    PL + + R G+ + L A V G PRP + W  
Sbjct: 400 ASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLH 459

Query: 771 NNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE--PTE 827
           N KP +  P  S  +   +T++ P+    D G Y L A+N  G A TS  + V+   P E
Sbjct: 460 NGKPFQ--PRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNE 517

Query: 828 -------ENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
                   + EP  P      +++++ E   ++L   +   P P + WY N   +  S  
Sbjct: 518 TSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESAD 577

Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI------------DVE 926
           +   F G+   L+I  V  E D+G YK VA NSAG++S    + +              E
Sbjct: 578 VQLLFQGDRCSLIIQEVYQE-DAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAE 636

Query: 927 KVTFVKHLQKSYE-------TEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973
           + +  K  Q  +E        +EG+ V+LE Q S    ++ +W+   KE+  +D R
Sbjct: 637 RQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQ-LDQR 691



 Score =  144 bits (348), Expect = 3e-32
 Identities = 200/791 (25%), Positives = 313/791 (39%), Gaps = 121/791 (15%)

Query: 501  PTSEEQSMAPIFVEKLRPKHTPD------------GSTVQFECQVEGYPRPQITWFRQTA 548
            P   E   A + VE L P   P             G  ++ E  V G PRP++ W     
Sbjct: 403  PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNG- 461

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608
              KP Q     Y+   V TL+I + +P DAG++   AKN AG A ++  +IV+  L +  
Sbjct: 462  --KPFQPRDSKYEYGRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 518

Query: 609  SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
            S+  +            A  +E I P      K   + EG  + L+C +V  PEP++ W 
Sbjct: 519  SDSEM------------ASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWY 566

Query: 669  FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
                 +    ++ +  + D    CS++ I  V +   G Y VVA+N  GEAS    LK+ 
Sbjct: 567  HNERPVKESADVQLLFQGDR---CSLI-IQEVYQEDAGHYKVVAINSAGEASSSCELKVT 622

Query: 729  T-GEKEP-----------PQVIEP-----LKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
               + EP           P+  +P     L  ++  +GE V+L  Q  G+   T  W   
Sbjct: 623  PLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLT 682

Query: 772  NKPVKA---LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE---- 823
            NK ++    + T+SD +      IL      D+GVYT+K  N  G A+  + + V+    
Sbjct: 683  NKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNA 742

Query: 824  -EPTEENAEPPLFINR-----FQEITVKEKG----TIKLVARVTRNPVPSITWYRNNEII 873
             E    +      I R     F+E+   ++G     IK    V   P P + W+ N++ +
Sbjct: 743  PENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPV 802

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTF 930
                 +     GE   L I  +  +   G   CVA N AGK++  A + I    +   + 
Sbjct: 803  HGHNFLVST-SGERQVLTIQKLTHDA-VGKISCVAENEAGKATCVAFLNIRGSGLPASSD 860

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS-------------TKWYHNKKEIS------GMD 971
            V+ + + + TE  + V ++ QT  T S             T+ +H+   I       G  
Sbjct: 861  VQTVSQEHNTESSR-VTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQ 919

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
              EI++                    K     Q +         IP+   +L+  E+  +
Sbjct: 920  RPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRR-EIAPR 978

Query: 1032 DVAILEVEINSETADVVWER--DG---EIIKPKKNKYDFEKRGHIR--------KLYIRN 1078
                L  +I  + ADV  E   DG     IK +KN     +  H R         + ++ 
Sbjct: 979  FTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQ 1038

Query: 1079 TSVHDEGEY----SCILRDESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT- 1131
              V D G Y    S  +   + TA++ V +   PP    RLQ Q   KG K T E+E+T 
Sbjct: 1039 VGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTG 1098

Query: 1132 KGDALVRWFKDGSEIQ---FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184
              +  V W KD   ++    S H +L   G   +L I      D+G+Y        G +K
Sbjct: 1099 LPEPTVTWLKDDKPLKDAGISEH-RLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAK 1157

Query: 1185 CTAILTVEEPS 1195
              A   + EPS
Sbjct: 1158 SIADCAILEPS 1168



 Score =  144 bits (348), Expect = 3e-32
 Identities = 122/426 (28%), Positives = 197/426 (46%), Gaps = 42/426 (9%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--NVAT 567
            P+ +E +  K  P+   V   CQV G P P++ W+R    + PS+  QM+YD+   +VA 
Sbjct: 8185 PLKIEFIEEKQ-PERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVAL 8243

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
             VI    P +A  ++  A+N  G A     ++          E+               +
Sbjct: 8244 EVINPT-PNEAVVYSVQAQNQFGRAIGNANILSRV------DEVP-------------RE 8283

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            IL+   PT +    A  V  G  +  E +   +P P++ W+  G EI+  EN    IE+ 
Sbjct: 8284 ILKA--PTVTPL-SAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREII--ENEETIIETT 8338

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEK-EPPQVIEPLKS 743
                 + +K+ N+ + + G Y V A N+ GEA      +V   K  E+ +PP+ I+PL+ 
Sbjct: 8339 ETT--TTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEP 8396

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPK-KVKDEG 801
                + E  I+ A V   P  +  W  +N+P+K+    +     +  T+L    + K  G
Sbjct: 8397 KYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVG 8456

Query: 802  VYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRN 859
             +T +AEN  G +  T+ V  + +   E  E P F+    Q + V +   + L  +VT  
Sbjct: 8457 PFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGK 8516

Query: 860  PVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
            P P + WY N E I+ ++  TI+Q+  G   +L IT V  E + G Y+CVA+N  GKS  
Sbjct: 8517 PTPKVEWYHNAEKITENKETTISQDLQGV-CQLQITEVFPE-NEGQYECVATNKIGKSVS 8574

Query: 918  GARVTI 923
               V I
Sbjct: 8575 KTNVKI 8580



 Score =  140 bits (339), Expect = 4e-31
 Identities = 97/359 (27%), Positives = 162/359 (45%), Gaps = 15/359 (4%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            L+ E ++ + + ++   + D     E   ++  + AP   +K R     +GS   F  +V
Sbjct: 1944 LLREVSFREAITRRSGYEQDSQLSQELDRNQGPAQAPQISQKPRSSKLIEGSDAVFTARV 2003

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
               P+P++TWF     +  SQ +++ Y    VATL ++     D G +T +A+N  G   
Sbjct: 2004 GSNPKPRLTWFHNGQRLVASQKYEISYSS-GVATLRVKNATARDGGHYTLLAENLQGCVV 2062

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653
            S+  L VE P ++   E               A     +PP F K    + + EG     
Sbjct: 2063 SSAVLAVE-PAAETAYEPKPVDVMAEQLEAGKA-----LPPAFVKAFGDREITEGRMTRF 2116

Query: 654  ECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            +CR+   P P++ WL  G ++  D +  + + ES  H     L ITNV +   G    +A
Sbjct: 2117 DCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHS----LMITNVTRLDAGAVQCLA 2172

Query: 713  VNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
             N+ GE ++   L +   E+   PQ ++   +M VR+GE + +SA  +G P+P ITW K+
Sbjct: 2173 RNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKD 2232

Query: 772  NKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
               + +   +  G     T L+  +V   D G Y   A+N  G     A + VE P E+
Sbjct: 2233 GVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQ 2291



 Score =  134 bits (323), Expect = 3e-29
 Identities = 129/571 (22%), Positives = 241/571 (42%), Gaps = 30/571 (5%)

Query: 832   PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-----ITQNFDGE 886
             PP F  + +   V E   + L  R+   P P I W  N E I   E      +T++    
Sbjct: 16056 PPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHM 16115

Query: 887   NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV---TIDVEKVTFVKHLQKSYETEEG 943
                +V  +   +   G Y+ +A+N  G++     +   T D E    ++ L ++    EG
Sbjct: 16116 YCSVVHISKVKKSQEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPL-RNMVIREG 16174

Query: 944   KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             ++V+L  Q       K  WY + K +      + +                 V  +  + 
Sbjct: 16175 ESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNPL- 16233

Query: 1002  KDQETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGE 1054
                ET+  L ++E        P F+ + ++  V +K    L  +++     +V W  +  
Sbjct: 16234 GSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNT 16293

Query: 1055  IIKPKKNKYDFEKRGHIRKLYIRNTSVH-DEGEYSCILRD---ESCTAEVTVVELPPEII 1110
              + P +         +I +L I++ +   D G+Y CI  +   ++      +VE+     
Sbjct: 16294 PLFPSERIQQVYDGENI-ELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTF 16352

Query: 1111  TRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
             T+   + +      +  +E  T      +WF +G E+   +H  +  DGK  KL I + +
Sbjct: 16353 TKKLKKTITIEEVQSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTN 16412

Query: 1170  LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
             L D+G Y+C+V   +  + + V +   +F   L ++ +   +T A L VE+  E  +VTW
Sbjct: 16413 LRDSGTYTCKVKKQETQSTVEVLQRKPDFIKVLEDYEVTEKDT-AILDVELTTEATEVTW 16471

Query: 1230  YKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288
             YK  + +  + +    I D K R L+IR  T  D+ +YTC +   + + +L V  +E PP
Sbjct: 16472 YKDGEKITPENKNVEFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVV--IELPP 16529

Query: 1289  KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
             +IV+   +  + +G +    V+         +W  N K I   +  + +ID K  SL I 
Sbjct: 16530 EIVEPLNDVAVTKGENAVFEVELSK-GDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIV 16588

Query: 1349  KVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             K +  D G Y +++      A + +   ++D
Sbjct: 16589 KAKPEDVGEYSVQVGEQTSKAKLTVEEPLVD 16619



 Score =  131 bits (316), Expect = 2e-28
 Identities = 104/388 (26%), Positives = 168/388 (43%), Gaps = 44/388 (11%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+F +K++P    +    +FE + EG P P + W+R++  I+ S D Q++      + L
Sbjct: 6029 APVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGK-SIL 6087

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            +IR+VF ED+  F+CVA+N  G A  +  L+V E   +  G                   
Sbjct: 6088 IIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQ---------------- 6131

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
                 PP+F    ++  V  G     + ++      D+ WL  G +I P     +  E  
Sbjct: 6132 -----PPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDS 6186

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----------GEKEPPQV 737
            +H     L I        G Y  VAVN  GEA       +++          G ++ P +
Sbjct: 6187 VH----TLLIIEPFAEDSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHI 6242

Query: 738  IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794
            +E LKS  V +G  VI   +V G P PT  W +     KP +       G+ + + ++  
Sbjct: 6243 VEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQMSRQGEYYQL-VISE 6301

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
               +DEG Y   AEN  G  +TSA + V  P  EN + P  I   ++++V E    +   
Sbjct: 6302 AFPEDEGTYKCVAENKLGSIQTSAQLKV-RPI-ENLDAPPTITALKDVSVTEGMPAQFKT 6359

Query: 855  RVT-RNPVPSITWYRNNEIISPSETITQ 881
             VT +    S+ W+R  ++I  +    Q
Sbjct: 6360 TVTGKVKATSVQWFREGQLIPETPDFQQ 6387



 Score =  120 bits (288), Expect = 6e-25
 Identities = 72/223 (32%), Positives = 119/223 (53%), Gaps = 18/223 (8%)

Query: 301   ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360
             IS  G +K    + +   EAA   K + +     D E+  +E+ +   ED ++  ++  E
Sbjct: 15787 ISMSGKVKLKKPIKKTFSEAADEAK-IKIIQDFDDGEEPIIEE-IRDDEDTIDEVEEPEE 15844

Query: 361   IIQEKQTLEEL---------PK------EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL 405
                E+   +E+         PK      ++  EQ+ I  R      +    D +T KK+ 
Sbjct: 15845 YFVEELPPDEVDFKLKPKKHPKPAYSVQDEEEEQFLIGIRHPKRDSVTYDEDSLTFKKKR 15904

Query: 406   NPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEE 465
                +  +   E    + ++++ +Y+A+ +EAINLVEGE++ ++   + +WWYV+K  TEE
Sbjct: 15905 KVVQQLFNE-ESENLNIMYSICNYIADNNEAINLVEGEKVTVVGRHSSEWWYVKKSTTEE 15963

Query: 466   KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM 508
             +GWVPAQYLM+   Y QY+Q KL+EKIDKLPVFE+    +Q +
Sbjct: 15964 EGWVPAQYLMEPEEYAQYVQNKLHEKIDKLPVFERKLLPKQKV 16006



 Score =  114 bits (275), Expect = 2e-23
 Identities = 88/363 (24%), Positives = 162/363 (44%), Gaps = 23/363 (6%)

Query: 636  FSKKPKAQYVDEGSD----ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            F+K  K ++++E       + + C++   P P++ W    EE++P E + +  +      
Sbjct: 8182 FTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDV 8241

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE--PPQVIEPLKSMIVR 747
               L++ N    +   Y+V A N+ G A  +  I+ ++    +E      + PL +++V 
Sbjct: 8242 A--LEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREILKAPTVTPLSAVVVP 8299

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
             G ++   A+  G PRP + W +N + +          T + T +K   +  K  G Y +
Sbjct: 8300 TGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTRKRTGKYEV 8359

Query: 806  KAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A+N  G A++S +V+  ++  +E  +PP FI   +     E     + A V   P+ S 
Sbjct: 8360 WAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSF 8419

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
             W+ +NE I  S  +          L+I N  S+   G + C A N  G  +  A V + 
Sbjct: 8420 QWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKF-VGPFTCRAENVGGSVTSTATVNLI 8478

Query: 924  ------DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREI 975
                  + E   FV+ L +  E  +G+ ++L CQ +   T   +WYHN ++I+      I
Sbjct: 8479 PQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTI 8538

Query: 976  IQE 978
             Q+
Sbjct: 8539 SQD 8541



 Score =  103 bits (246), Expect = 7e-20
 Identities = 120/526 (22%), Positives = 212/526 (40%), Gaps = 46/526 (8%)

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            ELI +  L  +  E T                 E  PP  ++K + +        +LEC+
Sbjct: 8053 ELIEDQQLIQNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECK 8112

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +  +P P+I W F    +   E   + +   +    + LKI  V     G YT  A N  
Sbjct: 8113 VEGVPFPEIKWYFNDILLFASEKYEITVMEQV----AKLKIAKVTPSDVGVYTCEAKNEA 8168

Query: 717  GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE--SVILSAQVVGNPRPTITWCKN--- 771
            G A+      I  G+   P  IE ++    +Q E   V ++ QV G P P + W +    
Sbjct: 8169 GVATSR--TNIILGKFTKPLKIEFIEE---KQPERLKVTVTCQVTGKPNPEVKWYRGIEE 8223

Query: 772  ---NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEEPT 826
               ++ V+    +  GD  ++ ++ P    +  VY+++A+N  G  I   + +  V+E  
Sbjct: 8224 VIPSETVQMFYDEKTGDV-ALEVINPTP-NEAVVYSVQAQNQFGRAIGNANILSRVDEVP 8281

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDG 885
             E  + P  +     + V   GT+   A+    P P + W RN  EII   ETI +  + 
Sbjct: 8282 REILKAPT-VTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTE- 8339

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTID------VEKVTFVKHLQKSY 938
                + + N+  +  +G Y+  A N  G++ S G+ V  D      ++   F++ L+  Y
Sbjct: 8340 TTTTIKVVNMTRK-RTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKY 8398

Query: 939  ETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
              E    +I     S  +S+ +W+ + + I   +   I+ +               VG  
Sbjct: 8399 FGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPF 8458

Query: 998  KCIVKD---QETSTM---LVVKETI-----PEFIRKL-QDFEVKEKDVAILEVEINSE-T 1044
             C  ++     TST    L+ +E       P F+ +L Q  EV + +  +L  ++  + T
Sbjct: 8459 TCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPT 8518

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
              V W  + E I   K     +    + +L I      +EG+Y C+
Sbjct: 8519 PKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECV 8564



 Score =  102 bits (245), Expect = 9e-20
 Identities = 143/668 (21%), Positives = 262/668 (39%), Gaps = 51/668 (7%)

Query: 1017  PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
             P+ +  L++  ++E +  +L  +I  +    V W +DG+ +K  K+  D     H   L 
Sbjct: 16160 PQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSDKDL----HTLTLI 16215

Query: 1076  IRNTSVHDEGEYSCI----LRDESCTAEVTVVEL------PPEIITRLQNQKVNKGNKAT 1125
                 S  ++GEY+      L     TA +T+ E       PP  + R + Q V +  +  
Sbjct: 16216 TPQKS--EKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIR 16273

Query: 1126  FEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSC----E 1179
                +++      V+W  + + +  S  IQ   DG+  +L I D + + D+G+Y C     
Sbjct: 16274 LPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIELIIKDANPETDSGDYKCIASNP 16333

Query: 1180  VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
             +G +   A + VE   + FT +L + I +       L  E     +   W+     +   
Sbjct: 16334 IGKTSHGARVIVEVDEVTFTKKLKKTITIEEVQSLTLECET-SHVVTTKWFFNGKELSGM 16392

Query: 1240  EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
             +   ++ D K   L+IR     D   YTC +   K  T+  VEV++  P  +    +Y +
Sbjct: 16393 DHRVVVEDGKTHKLVIRNTNLRDSGTYTCKV--KKQETQSTVEVLQRKPDFIKVLEDYEV 16450

Query: 1300  KRGSDVTLLVDYQAFPQPND-EWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
                   T ++D +   +  +  W  +  KI  + K+ +   D K+  L I+ V   D G 
Sbjct: 16451 TEKD--TAILDVELTTEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIHDEGQ 16508

Query: 1358  YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             Y  ++E      +    + +++ P    +P + ++  +       E E +    ++ +  
Sbjct: 16509 YTCKIEGQ----ECSCELVVIELPPEIVEP-LNDVAVTKGENAVFEVELSKGDALVKWFK 16563

Query: 1418  EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
               +EI   E I +    K Q S++ +K           V E  +    +T++    ++E 
Sbjct: 16564 NGKEIVFNERIQLAIDGKKQ-SLRIVKAKPE------DVGEYSVQVGEQTSKAKLTVEEP 16616

Query: 1478  KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRX 1533
              +    +  P   + T+   D E T      P  +VTW + GK +K  +           
Sbjct: 16617 LVDF-VIRLPDITLATKTT-DAEFTVQLSQ-PDVEVTWCKKGKPIKPNQKHEVFVEGTVR 16673

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                             C+A N     +  CV  ++  PVIT S++D   K K  D+   T
Sbjct: 16674 RLVIHDASDEDAGEISCVAENVTSSTKL-CVEELKLPPVIT-SDKDQTIKVKENDDVTFT 16731

Query: 1594  AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
                 G+P PE  W      +   K    T  E+++ + IK+   S   K    +    G 
Sbjct: 16732 VKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFGGI 16791

Query: 1654  SSVEVTLK 1661
                +VT K
Sbjct: 16792 PEPKVTWK 16799



 Score =  101 bits (243), Expect = 2e-19
 Identities = 111/458 (24%), Positives = 194/458 (42%), Gaps = 54/458 (11%)

Query: 676  PDENISVAIESDMHMYCSVLKITNVKKFQ-----EGTYTVVAVNREG---EASLPIVLKI 727
            P +N+   I S+ + Y S+ +   V  F+     E ++      R G   ++ L   L  
Sbjct: 1913 PIQNLEKNIYSNGYSYTSIEEEFRVDTFEYRLLREVSFREAITRRSGYEQDSQLSQELDR 1972

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
              G  + PQ+ +  +S  + +G   + +A+V  NP+P +TW  N + + A        + 
Sbjct: 1973 NQGPAQAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSS 2032

Query: 788  SITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE---------EPTEENAE----- 831
             +  L+ K    +D G YTL AEN +G   +SAV+ VE         +P +  AE     
Sbjct: 2033 GVATLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAG 2092

Query: 832  ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGE 886
               PP F+  F +  + E    +   RVT NP P + W  N   +    S  I  N  G 
Sbjct: 2093 KALPPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGS 2152

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQK--SYETEEG 943
            +  L+ITNV + +D+G  +C+A N AG+ +  A++ + + E+V   + +Q+  +    EG
Sbjct: 2153 H-SLMITNV-TRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 2210

Query: 944  KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            + + +      T   +  W  +  +IS    R +  +G             D G  +C  
Sbjct: 2211 EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 2270

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
            ++   ST    +  + E  R+  ++E +  ++                 R  ++I+P   
Sbjct: 2271 QNIAGSTANRARLYV-EVPREQPNYEQRRLNL----------------PRPTKVIEPGAR 2313

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
                 K G I  L + +   HD GEY C + + S  AE
Sbjct: 2314 ATSVFKFGFI-ALDLLSIMGHDSGEYMCRVTNASGVAE 2350



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 147/637 (23%), Positives = 240/637 (37%), Gaps = 90/637 (14%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F++  K     EG   + EC +   PEP + W   G  I  + +     +  +   C 
Sbjct: 225  PLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGI---CR 281

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQG 749
             L I          ++  A N  G       L ++    E    PP+++  L+S    +G
Sbjct: 282  -LVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEG 340

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
             S   +  V G P PT+ W KN+K +   P       +    LK ++V  +D+ VYT  A
Sbjct: 341  SSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSA 400

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  GI   SA + V EP E   E P F         +    IKL A V   P P + W 
Sbjct: 401  SNPAGIEHCSASLIV-EPLEP-TELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 458

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923
             N +   P ++    ++   + L+I       D+G Y   A N AG++     V +    
Sbjct: 459  HNGKPFQPRDS---KYEYGRVTLIIPQAYPN-DAGSYVLSAKNLAGEAYTSCNVIVKGRL 514

Query: 924  -----------DVEKVTFVKHLQ-KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969
                       D+E +    HL  K     EGK V L+C        +  WYHN++ +  
Sbjct: 515  PNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKE 574

Query: 970  MDHREIIQEGRXXXXXXXXXXXXDVGVIKCI------------------VKDQETST--- 1008
                +++ +G             D G  K +                  +   E +T   
Sbjct: 575  SADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQ 634

Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVW-ERDGEIIKPKKNKY 1063
                 + K++ P+F R L D    E +  +LEV+ +  +     W   + E+   ++   
Sbjct: 635  AERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITT 694

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV--VELPP---------E 1108
              +    + KL + N S  D+G Y+  +     D  C + + V  V  P          E
Sbjct: 695  QSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVE 754

Query: 1109 IITRLQNQKVNK--GNKATFEIELTKGDALVR--------WFKDGSEIQFSNHIQLTIDG 1158
            II R Q  +  +   +K     E+ K + +V+        WF +   +   N + ++  G
Sbjct: 755  IIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFL-VSTSG 813

Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191
            ++Q L I     D  G+ SC    E G + C A L +
Sbjct: 814  ERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNI 850



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 99/384 (25%), Positives = 156/384 (40%), Gaps = 43/384 (11%)

Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEK---PTSEEQSMAPIFVEKLRPK-HTP-- 522
           +P  Y  D  +Y    +    E      V  K   P     S     +E ++P  H P  
Sbjct: 480 IPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLK 539

Query: 523 -----DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
                +G  V+ +C + G P P++ W+     +K S D Q+ +  D   +L+I+EV+ ED
Sbjct: 540 DVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDR-CSLIIQEVYQED 598

Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
           AG +  VA N+AG ASS+ EL V  PL+                      + +   P F 
Sbjct: 599 AGHYKVVAINSAGEASSSCELKV-TPLNQ--------AEPATRAQAERQSLPKDSQPKFE 649

Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
           +       DEG  ++LE +          W    +E+  D+ I+   +S++ ++  +L  
Sbjct: 650 RLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLIL-- 707

Query: 698 TNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGE-----KEPPQVIE-----PLKSM 744
            NV    +G YTV   N  G+A   S  IV  +   E     +   ++IE       K +
Sbjct: 708 NNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKEL 767

Query: 745 IV-RQGE--SVI-LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798
              +QGE   VI     V G P P + W  N++PV        + G+   +TI K     
Sbjct: 768 FSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTH-D 826

Query: 799 DEGVYTLKAENSEGIAETSAVITV 822
             G  +  AEN  G A   A + +
Sbjct: 827 AVGKISCVAENEAGKATCVAFLNI 850



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 81/306 (26%), Positives = 125/306 (40%), Gaps = 22/306 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+KK +   V E      E      P P + W     E  P +N S  ++       S
Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWY---RESFPIQN-SPDLQIHTFSGKS 6085

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT------GEKEPPQVIEPLKSMIVR 747
            +L I  V       ++ VA NR G A     L ++       G  +PP  +  ++S  V 
Sbjct: 6086 ILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVA 6145

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTK--SDGDTHSITILKPKKVKDEGVYT 804
             G+     A+V G     + W KN   ++ ++  K   +   H++ I++P   +D G Y 
Sbjct: 6146 TGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPF-AEDSGRYE 6204

Query: 805  LKAENSEGIAETSAVITV------EEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVT 857
              A N+ G A       V      E+PT   +E  P  + + +  TV+E   +    RV 
Sbjct: 6205 CVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVD 6264

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              P P+  W R    + PS     +  GE  +LVI+    E D G YKCVA N  G    
Sbjct: 6265 GKPTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPE-DEGTYKCVAENKLGSIQT 6323

Query: 918  GARVTI 923
             A++ +
Sbjct: 6324 SAQLKV 6329



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 45/115 (39%), Positives = 64/115 (55%), Gaps = 2/115 (1%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            EKPT+     AP  VE+L+ +   +GS V F C+V+G P P   W R    +KPS+ FQM
Sbjct: 6229 EKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQM 6288

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
                +    LVI E FPED GT+ CVA+N  G   ++ +L V  P+ +  +  T+
Sbjct: 6289 SRQGE-YYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVR-PIENLDAPPTI 6341



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 125/637 (19%), Positives = 252/637 (39%), Gaps = 42/637 (6%)

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
            + +++G+ Q L+    +++   E S E+     T +   E+    F +   + I +    
Sbjct: 7944 EASVEGQPQLLEAAIAEIEKVDEISQEISQKTITLLKKTEDTRPQF-ITTEQLIELDVE- 8001

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCVL 1270
            D    +E+   +  +   K++ V++D++    +  + ++ +   I K  +++  E   ++
Sbjct: 8002 DVRRDLEMKVTSNIIKKEKRRVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLI 8061

Query: 1271 LDAKSTTKLKV-----EVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319
             + + TT  +V     ++V+       PP+I +  R  +        L    +  P P  
Sbjct: 8062 QNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECKVEGVPFPEI 8121

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +W  N  ++   +  + ++  + A L I KV  +D G+Y    +N  G A    N+ IL 
Sbjct: 8122 KWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNI-ILG 8180

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTG--NSTIIYY--VVEYQEIDTTEWISVKNITK 1435
            K + P K   +E             + TG  N  + +Y  + E    +T +    +    
Sbjct: 8181 KFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGD 8240

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
                + N   N +  +   A N+    I +A+  +   +V +E  +++PTV  PL  +  
Sbjct: 8241 VALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI-LKAPTV-TPLSAVVV 8298

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549
                 +     + G+P+P+V W R+G+++    +T   T E                 Y+
Sbjct: 8299 PTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTRKRTGKYE 8358

Query: 1550 CIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKVGDE-WLVTAVIEGIPPPE 1603
              A N  GE ++S  VV   QKP   I      + ++ K+    E  ++ A++E  P   
Sbjct: 8359 VWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSS 8418

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
              W+ +   +++  E  I ++   S + I+  +      +T  A N  G  TS+  V L 
Sbjct: 8419 FQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATVNLI 8478

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
              ++  + E P  + E+      ++    +D   L LT     K  P    +     +  
Sbjct: 8479 PQEEAEEFESPRFVEEL------VQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITE 8532

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            + ET   Q L   C+     +     G  E + +  I
Sbjct: 8533 NKETTISQDLQGVCQLQITEVFPENEGQYECVATNKI 8569



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 87/339 (25%), Positives = 141/339 (41%), Gaps = 40/339 (11%)

Query: 512   FVEKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
             FV +L P  T    T   E  V+   P  ++TW ++   IKP+Q  +++ +   V  LVI
Sbjct: 16620 FVIRL-PDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQKHEVFVEG-TVRRLVI 16677

Query: 571   REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL--SDHGSEMTVXXXXXXXXXXXXADI 628
              +   EDAG  +CVA+N         E +   P+  SD    + V              +
Sbjct: 16678 HDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGV 16737

Query: 629   LEG----------IP------PTFSKKP-----KAQYVDE-GSDILLECRLVAIPEPDIA 666
                          IP      PT  ++      K   V E   ++ L C    IPEP + 
Sbjct: 16738 PTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFGGIPEPKVT 16797

Query: 667   WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
             W   G+     E+ S+  E+ +  Y   ++ T ++   E TYT VA N +G A     LK
Sbjct: 16798 WKKNGQVF---ESRSIRYENRVAKY--TIEKTTIET--EATYTCVATNEKGSAETSCRLK 16850

Query: 727   IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK---NNKPVKALPTKSD 783
             ++  +K   +V +   +  +R G  + + A V G P+PT+TW K     K  K++  ++ 
Sbjct: 16851 LQ--QKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWHKETIEQKTTKSVTIETT 16908

Query: 784   GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
               T + T+ K  + +  G Y + A N  G       + V
Sbjct: 16909 ETTSTYTVKKVTR-EQSGKYKVTATNESGTTYVECTVQV 16946



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 51/205 (24%), Positives = 100/205 (48%), Gaps = 11/205 (5%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            I P F+     + VD+G+D+ +E      P P+I     G ++  D +  ++ + +    
Sbjct: 975  IAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNR--- 1031

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               +++  V     G Y V A N  G+++    L +K     PP     L++ + ++GE 
Sbjct: 1032 -VTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKK-TIFPPVFGRRLQAQVSKKGEK 1089

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVYTLK 806
            + +  +V G P PT+TW K++KP+K          + G+++ + I++  +  D G Y ++
Sbjct: 1090 LTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL-IIEKAQTTDSGKYMVR 1148

Query: 807  AENSEGIAETSAVITVEEPTEENAE 831
            A N+ G A++ A   + EP+ E  +
Sbjct: 1149 ATNAGGEAKSIADCAILEPSPERLQ 1173



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 52/186 (27%), Positives = 84/186 (45%), Gaps = 6/186 (3%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
             VTW K   V E +      + V K T  I K T + +  YTCV  + K + +    +   
Sbjct: 16796 VTWKKNGQVFE-SRSIRYENRVAKYT--IEKTTIETEATYTCVATNEKGSAETSCRLKLQ 16852

Query: 1287  PPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
                +++ E +Y   +++ GS +T+    + +PQP   W   +   K  K         ++
Sbjct: 16853 QKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWHKETIEQKTTKSVTIETTETTS 16912

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             + T+KKV    +G YK+   N  G   VE  V ++DKPS P    I +I   SI + W  
Sbjct: 16913 TYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDKPSRPQSLEIKDIKKDSIVLEWTP 16972

Query: 1404  PENTGN 1409
             P + G+
Sbjct: 16973 PVDDGD 16978



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 75/323 (23%), Positives = 131/323 (40%), Gaps = 35/323 (10%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P    ++Q  +V +  +A FE+E   + +  V+W+++   IQ S  +Q+     K  L I
Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 6089

Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEP--SINFTLRLPEFILVPANT------- 1212
                ++D+  +SC      G +KC+A L VEE   +    ++ P F+    +T       
Sbjct: 6090 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 6149

Query: 1213 ---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
               DA +T   P   LDV W K    I+ + KF ++ +    TL+I +   +D   Y CV
Sbjct: 6150 ARFDAKVTGTRP---LDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 6206

Query: 1270 LLDAKSTTKLKVE-VVEFP--------------PKIVDYEREYRIKRGSDVTLLVDYQAF 1314
             ++A    +   + +V+ P              P IV+  +   ++ GS V         
Sbjct: 6207 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 6266

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P   W+     +K  ++ + S   +   L I +    D G YK   EN  G       
Sbjct: 6267 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 6326

Query: 1375 VTILDKPSPPGKPNILEIDSSSI 1397
            + +    +    P I  +   S+
Sbjct: 6327 LKVRPIENLDAPPTITALKDVSV 6349



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 76/249 (30%), Positives = 125/249 (50%), Gaps = 21/249 (8%)

Query: 160   DSQEDESKPDVSQPPQNIIEEAKSEPKLIEES-EQPIAKTSEIDNEVPEKINVPDDKETS 218
             ++ ED +KP  S+  + + ++     +LI++  EQ I KT   + E  EKI     K+  
Sbjct: 14267 ETVEDVTKPK-SKKKKVVKKKTDDHDELIKKMLEQEIEKT---ELEKYEKIEFDVPKKLK 14322

Query: 219   QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278
                    + + L PIKIERKE + +     +  D P+               E + V+LP
Sbjct: 14323 P------EFAALEPIKIERKEQKPTKVTILDATDVPKTVKLKPSKRKEKPAEELT-VQLP 14375

Query: 279   KFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVE- 337
             KF+LK+R+  +  +PP  + P  + +G+IK NG LSRNI+EA ++ K  F P K   ++ 
Sbjct: 14376 KFRLKARM-VLVEYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILK--FKPHKTKKIKK 14432

Query: 338   -KTELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQ-KID 393
              K +LE+  L  YE  + S+++  E    K+  E+ PK E+  E   +   K   + K +
Sbjct: 14433 IKDDLEKVELEKYEKYISSEEEPEEKTPYKKP-EKAPKPEEKQEDVKLKLGKGKKKPKEE 14491

Query: 394   EIVDEVTIK 402
             E  + VT+K
Sbjct: 14492 EAPENVTLK 14500



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 87/403 (21%), Positives = 157/403 (38%), Gaps = 30/403 (7%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P+P  EW  +   I+     K + D     L I++    D+  +  R  N  G  D    
Sbjct: 252  PEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNAT 311

Query: 1375 VTILDKPS-----PPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTE 1426
            +++ +  +     PP     L+   ++    +            T+ ++  +    D+ +
Sbjct: 312  LSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPD 371

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
            ++   N  +     + +       +   A N   I   S +    + ++ T++  P+ + 
Sbjct: 372  YVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL-IVEPLEPTEL--PSFKV 428

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXX 1545
            PL N      + I+L  I GG+P+P+V W  +GK  +   + YE  R             
Sbjct: 429  PLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDA 488

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQK-PVITISNE---DIKQ-KHKV-----------GDE 1589
              Y   A N  GE  TSC V ++ + P  T  +E   DI+  K  V           G  
Sbjct: 489  GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKP 548

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
              +  VI G P PEVIWY N   ++   +  +  +     + I+E+ +  +  Y + A N
Sbjct: 549  VRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAIN 608

Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
            +AG +S    LKV   P     P    +  R+S+  + +P  +
Sbjct: 609  SAGEASSSCELKV--TPLNQAEPATRAQAERQSLPKDSQPKFE 649



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 73/280 (26%), Positives = 127/280 (45%), Gaps = 19/280 (6%)

Query: 335  DVEKTELEQPLFSYEDIV--ESKKDENEIIQEKQT--LEELPKEDVPEQYTITPRKSSAQ 390
            DV+   + + +   E++V  E   +  +   +K+T  L+E   E  P+   +    +  +
Sbjct: 7905 DVKVVAVSEDVLPEEEVVPTEETPEAKQKAHKKRTKRLKEASVEGQPQ--LLEAAIAEIE 7962

Query: 391  KIDEIVDEV-----TIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGE-R 444
            K+DEI  E+     T+ K+       +   E      V  V   + E     N+++ E R
Sbjct: 7963 KVDEISQEISQKTITLLKKTEDTRPQFITTEQLIELDVEDVRRDL-EMKVTSNIIKKEKR 8021

Query: 445  LYILDTSN---QDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKP 501
              +LD S    +     QK + E    V  + L+++    Q  Q+    ++         
Sbjct: 8022 RVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLIQNQQETTTSEVIGQERKLVK 8081

Query: 502  TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
              +++   P   EKLRP+   P+  TV  EC+VEG P P+I W+    ++  S+ +++  
Sbjct: 8082 KKKKEIKPPRITEKLRPRQCVPEEPTV-LECKVEGVPFPEIKWYFNDILLFASEKYEITV 8140

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             +  VA L I +V P D G +TC AKN AG A+S T +I+
Sbjct: 8141 MEQ-VAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIIL 8179



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 88/343 (25%), Positives = 148/343 (43%), Gaps = 30/343 (8%)

Query: 83    EPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXX-----XX 137
             E   V+LPKF+LK+R+  + ++PP  + P  T +G+IK NGELSRN++EA          
Sbjct: 14368 EELTVQLPKFRLKARMVLV-EYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILKFKPHK 14426

Query: 138   XXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAK 197
                      DLE+V LEK + + S E+E  P+   P +   +  K E K  E+ +  + K
Sbjct: 14427 TKKIKKIKDDLEKVELEKYEKYISSEEE--PEEKTPYKKPEKAPKPEEKQ-EDVKLKLGK 14483

Query: 198   TSE--IDNEVPEKINVPDDKETSQTPTSFNKRSKL--TPIKIERKEMEVSTPQHAETVDG 253
               +   + E PE + +   K   Q P    +  +L   P ++E  E +   P+  E V  
Sbjct: 14484 GKKKPKEEEAPENVTL---KNIPQKPQEVEEEVELKQKPKEVEIVEEQTKKPKDGEFVVE 14540

Query: 254   PQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGIL 313
             P                E   ++ P+   K +    T + P+      S   +I    + 
Sbjct: 14541 P--FEPSEFDRPEYVPDELEQIEHPEIPEKVKKPSKTKYKPKDKSK--SEPETIVSEIVA 14596

Query: 314   SRNIKEAAKVKKQV-FVPPKLPDVEKTELEQPLFSYEDIVESKKDEN---EIIQEKQTLE 369
                 +E A  ++ V F  P+    E+T+ E  L     + ++ KDEN   + +   +  E
Sbjct: 14597 GVPKEEEAIPEQDVKFRKPERDAPEETDSEIKL---RPVPQASKDENPDEQALVTPKAEE 14653

Query: 370   ELPK--EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEI 410
              +P+  ED        P+KS  +K+     E+  K+    FE+
Sbjct: 14654 PIPQEIEDKAIDDEKKPKKSKPKKVQPKEQEIA-KEEPEEFEV 14695



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 12/207 (5%)

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATY 1529
            +  E +  SP   +PLK+  +   +     C   G P+P V W++DG  ++T    K T+
Sbjct: 216  IFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTF 275

Query: 1530 ENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQ----- 1582
            +                  + C A N  G  +T+  + +++    + +    I +     
Sbjct: 276  DKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSG 335

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K   G  +    V+ G+P P V W+KN   +++  +Y I+     + ++ +E+     + 
Sbjct: 336  KATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 395

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            YT  ASN AG      +L V  +P +P
Sbjct: 396  YTCSASNPAGIEHCSASLIV--EPLEP 420



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 93/408 (22%), Positives = 171/408 (41%), Gaps = 39/408 (9%)

Query: 1001 VKDQETSTMLVVKETIPEF---IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
            +++Q T   L  ++   E    I+ L+D   +E++V +    I  E   +  E +  I +
Sbjct: 111  IREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQN--IRDEETRIRREEEERIRR 168

Query: 1058 PKKNKYDFEKRGHIRKLYI-RNTSVHDEGEYSCIL-----RDESCTAEVTVVELPPEIIT 1111
              +++   E+   I++  I R  ++ D+ +   I+     +D    +  T +     + T
Sbjct: 169  ENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFT 228

Query: 1112 R-LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
            R L++    +G++  FE E+T   +  V WFKDG  IQ ++  + T D    +L I +  
Sbjct: 229  RPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETF 288

Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTL---RLPEFILVPANTD------AYL 1216
              D+  +SC     VG     A L+V E +    L   R+  F+     T+      A +
Sbjct: 289  AADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACV 348

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS- 1275
               +P  T  V W+K    I+D+  + +  +  + TL   +   +D   YTC   +    
Sbjct: 349  VAGVPLPT--VQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGI 406

Query: 1276 ---TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
               +  L VE +E P ++  ++        + G  + L       P+P   W+ N K  +
Sbjct: 407  EHCSASLIVEPLE-PTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQ 465

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              + +K   +    +L I +    DAG Y L  +N  G A    NV +
Sbjct: 466  P-RDSK--YEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIV 510



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 89/363 (24%), Positives = 145/363 (39%), Gaps = 57/363 (15%)

Query: 520  HTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
            +T +G    FEC++E    P  ++ WF+    I     F+  +D   VA L I  +  ED
Sbjct: 3071 NTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHDFGYVA-LDIVHLIAED 3129

Query: 578  AGTFTCVAKNAAGFASSTTEL-------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630
            +G +TC A N  G   +  EL       IV    ++ G E  +             +I E
Sbjct: 3130 SGVYTCRAVNLIGSDETQVELQCRSGEQIVTVTQNEAGLEQ-IHYLEDRSRYTRREEIDE 3188

Query: 631  GIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIES 686
                 P F+   K   + E      ECRL+ + +P   + W       +P ++ S   E+
Sbjct: 3189 STKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNN---LPLKSGSRFTET 3245

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREG----------------------EASLPIV 724
            +   + + L I +      GTYT  A N  G                      E +LP +
Sbjct: 3246 NNFGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRL 3304

Query: 725  LKIKTGEK------------EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCK 770
              ++ G K            + P    P++ + V + ++V   A++  VG+P+ T+ W +
Sbjct: 3305 QHLEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLR 3364

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            N +P++A    +         L  K V  +D G YT +A N  G A TSA + V+  T  
Sbjct: 3365 NGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSI 3424

Query: 829  NAE 831
              E
Sbjct: 3425 QLE 3427



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 22/262 (8%)

Query: 484  LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQ 540
            L+K  N +   +   E+ T E +  AP+F   L   ++  +G    FE ++     P+ +
Sbjct: 5011 LEKIANLEYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLK 5070

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            + W+     +K    F+ + D   V  L I  V+PED+G ++C A N  G A +T  + +
Sbjct: 5071 VEWYWNGRPLKAGSRFRTFCDFGFVI-LEISPVYPEDSGEYSCRAINEYGEAVTTATMKI 5129

Query: 601  EAPLS-------DHGSEMTVXXXXXXXXXXXXA-----DILEGIPPTFSKKPKAQYVDEG 648
            +   S         G E T+            +     D   G PP F   P    + E 
Sbjct: 5130 QGKRSIIMESQLPKGMEGTIDRIAELEGLGSRSTEFVPDDDTGKPPEFITSPFDMVIGEN 5189

Query: 649  SDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            +    ECRL  I +P   + W   G+ +     I     +D      +L+I    +   G
Sbjct: 5190 ALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTI--NDFGFV--ILEIAGCYQRDSG 5245

Query: 707  TYTVVAVNREGEASLPIVLKIK 728
             YT  A N+ GEA++   L++K
Sbjct: 5246 LYTCKATNKHGEATVSCKLQVK 5267



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 94/422 (22%), Positives = 166/422 (39%), Gaps = 53/422 (12%)

Query: 774  PVKALPTKSDGDTHS--ITILKPKKVKDEGVYTLKAENSEGIAETSAVI---TVEEPTEE 828
            P K +   S+   H   + + K ++V+ E    L+        ET+ V    T++E   +
Sbjct: 5962 PPKGIAQPSESSVHGREVHMNKQQQVQKEIQGDLEITRKITATETTEVEHKGTIQERVVQ 6021

Query: 829  N----AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNF 883
                 A+ P+F  + Q   V E    K        P P++ WYR +  I  S  +    F
Sbjct: 6022 GPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTF 6081

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHL 934
             G++I L+I  V  E DS  + CVA N  G +   A + ++         ++  +FV  +
Sbjct: 6082 SGKSI-LIIRQVFVE-DSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTI 6139

Query: 935  QKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
            Q S     G+    + + + T  +   W  N  +I      ++++E              
Sbjct: 6140 Q-STTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE 6198

Query: 993  DVGVIKCIVKDQETSTML----VVK-------------ETIPEFIRKLQDFEVKEKDVAI 1035
            D G  +C+  +           +V+             E  P  + +L+   V+E    I
Sbjct: 6199 DSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVI 6258

Query: 1036 LEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
                ++ + T    W R    +KP +  +   ++G   +L I      DEG Y C+  ++
Sbjct: 6259 FRCRVDGKPTPTARWMRGENFVKPSRY-FQMSRQGEYYQLVISEAFPEDEGTYKCVAENK 6317

Query: 1095 ------SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELT-KGDAL-VRWFKDGS 1144
                  S   +V  +E    P  IT L++  V +G  A F+  +T K  A  V+WF++G 
Sbjct: 6318 LGSIQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQ 6377

Query: 1145 EI 1146
             I
Sbjct: 6378 LI 6379



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 66/250 (26%), Positives = 101/250 (40%), Gaps = 26/250 (10%)

Query: 480  YTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538
            Y  + + K+ E K     V      +EQ   P F++ L PK+  +      E  VE  P 
Sbjct: 8357 YEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPL 8416

Query: 539  PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
                WF     IK S + ++     N +TL+I     +  G FTC A+N  G  +ST  +
Sbjct: 8417 SSFQWFVHNEPIKSSNEVRI-VSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATV 8475

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
             +  P  +                   A+  E  P    +  +   V +G  +LL C++ 
Sbjct: 8476 NL-IPQEE-------------------AEEFES-PRFVEELVQPVEVMDGEALLLTCQVT 8514

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
              P P + W    E+I   EN    I  D+   C  L+IT V    EG Y  VA N+ G+
Sbjct: 8515 GKPTPKVEWYHNAEKIT--ENKETTISQDLQGVCQ-LQITEVFPENEGQYECVATNKIGK 8571

Query: 719  ASLPIVLKIK 728
            +     +KI+
Sbjct: 8572 SVSKTNVKIQ 8581



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 107/435 (24%), Positives = 174/435 (40%), Gaps = 55/435 (12%)

Query: 996  VIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
            V + I KD Q  S    ++   P F R L+D   +E D  + E E+       V W +DG
Sbjct: 203  VTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDG 262

Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-------- 1102
              I+   + K  F+K   I +L I  T   D   +SC   +   +C    T+        
Sbjct: 263  ISIQTNSDYKTTFDKG--ICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAE 320

Query: 1103 VEL-PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159
            V+L PP I+  LQ+ K  +G+   F   +  G  L  V+WFK+   I  S    ++ +  
Sbjct: 321  VQLVPPRILRFLQSGKATEGSSFQFAC-VVAGVPLPTVQWFKNDKCIDDSPDYVISYNNG 379

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVE--EPSINFTLRLPEFILVPANTD 1213
            +  LK  +  L+D   Y+C   N      C+A L VE  EP+      LP F +  +N  
Sbjct: 380  EATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPT-----ELPSFKVPLSNAM 434

Query: 1214 AYLTVEIPDETL-------DVTWYKKKSVIEDTE------KFTLI------SDVKKRTLI 1254
            A +  +I  E +       +V W       +  +      + TLI      +D     L 
Sbjct: 435  ARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLS 494

Query: 1255 IRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
             +    +       +    L +  S +++  ++    P +    ++  I  G  V L   
Sbjct: 495  AKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCV 554

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA- 1369
                P+P   W  N + +K+    +        SL I++V   DAG YK+   N+ G A 
Sbjct: 555  IVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEAS 614

Query: 1370 -DVEMNVTILDKPSP 1383
               E+ VT L++  P
Sbjct: 615  SSCELKVTPLNQAEP 629



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 84/354 (23%), Positives = 145/354 (40%), Gaps = 29/354 (8%)

Query: 1474  IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
             ++ T  ++P + +PL+N+     E + L+    G P PKVTWY+DGK +K AK+  ++  
Sbjct: 16152 VRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSD-KDLH 16210

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVITISNEDIKQKHKVG 1587
                           Y   A N  G VET+  + I++      +P + +   + +   + G
Sbjct: 16211 TLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKG 16270

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
              E  + A + G P PEV W  N   L  +++   +   E   +I       + S  Y   
Sbjct: 16271 -EIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIELIIKDANPETDSGDYKCI 16329

Query: 1647  ASNTAGTSS------VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
             ASN  G +S      VEV    + K  K +  + + E+  +S+T+E     +   +  TK
Sbjct: 16330 ASNPIGKTSHGARVIVEVDEVTFTK--KLKKTITIEEV--QSLTLE----CETSHVVTTK 16381

Query: 1701  YAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
             +     E    +  + V D            L ++  Y  +V  Q      E L+ +P  
Sbjct: 16382 WFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKKQETQSTVEVLQRKPDF 16441

Query: 1760  IKTALDVP-SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK-VEIKQEGK 1811
             IK   D   +          +  E+  +TW+   K+G     + K VE  ++GK
Sbjct: 16442 IKVLEDYEVTEKDTAILDVELTTEATEVTWY---KDGEKITPENKNVEFIKDGK 16492



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 61/269 (22%), Positives = 106/269 (39%), Gaps = 20/269 (7%)

Query: 498  FEKPTSEEQSM--APIFVEKL-RPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKP 552
            +++   EE ++  AP+FV KL  P +  +G +  +EC++E YP P  ++ WF     +  
Sbjct: 3446 YQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKPLST 3505

Query: 553  SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--------SSTTELIVEAPL 604
               F+  YD    A L I  V+ ED+G +TC   N  G A        +S + +I E   
Sbjct: 3506 GHRFRTTYDF-GFAALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNVTSRSSIIHETQH 3564

Query: 605  SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP- 663
             +  +++               +      P F +  +   V+EG+ + LE  L+ + +P 
Sbjct: 3565 EEALTKIQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPT 3624

Query: 664  -DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722
              + W   G  I          +         L I        GTY   A N  GEA   
Sbjct: 3625 MKVEWYCNGRPIQTGHRFKTTYDFGF----VALDILYAHAEDTGTYMCKAKNAIGEAVTT 3680

Query: 723  IVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              + +   +      ++  +   +RQ E+
Sbjct: 3681 CAVNVTANKTLDLDTLDAQRLEKIRQLET 3709



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 67/257 (26%), Positives = 105/257 (40%), Gaps = 24/257 (9%)

Query: 481  TQYLQKKLNEKIDKLP--VFEKPTSEEQSMA---PIFVEKLR-PKHTPDGSTVQFECQVE 534
            T  + + L EK   L    F +P  + + ++   P+FV  L  PK   DG  +  EC++E
Sbjct: 2760 TSSMHRGLYEKTQNLENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLE 2819

Query: 535  --GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
              G P  ++ WF     +     F+ YYD   VA  +I+     D+G +T  A N  G A
Sbjct: 2820 PMGDPTMRVEWFHNGRPVTVGSRFRTYYDFGFVALDIIKAT-AADSGEYTVRATNHLGTA 2878

Query: 593  SST--------TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
             ++        T+++ E   ++   E                DI     P F++      
Sbjct: 2879 HTSACVRVIDHTDVVTETQ-NEQSLEQIQLLEDSRRRHHQEEDITIMQAPQFTRGLHNIE 2937

Query: 645  VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
              EG+++ LECRL  + +P   I W   G+ +        A E D   Y + L +     
Sbjct: 2938 TIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFD---YVA-LDLLGCYA 2993

Query: 703  FQEGTYTVVAVNREGEA 719
               G YT  A N+ GEA
Sbjct: 2994 IDSGVYTCQARNQLGEA 3010



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 93/376 (24%), Positives = 150/376 (39%), Gaps = 56/376 (14%)

Query: 496  PVFEKPTSEEQSMA-PIFVEKLR-PKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIK 551
            P+  +PT  E+    PIF + L  P    +G+   FE +V   G P  +  WF     ++
Sbjct: 4109 PLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSLKFEWFINGVELQ 4168

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
                 +  +D   V TL I  V PEDAG + C A NAAG A S+T + V+   +  G  +
Sbjct: 4169 MGSRLRTTHDFGFV-TLDITAVVPEDAGVYMCRAYNAAGEAVSSTAMKVKTKSNIDGQPL 4227

Query: 612  TVXXXXXXXXXXXXAD-----ILEGIP---PTFSKKPKA-QYVDEGSDILLECRLVAIPE 662
                           +      ++  P   P F+   ++   + EG  +LLE ++    +
Sbjct: 4228 IPESWEAIRLKEAAMNRVPEMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRAD 4287

Query: 663  PD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA- 719
            P+  I W   G  +         I S        L I  ++      YT  A N+ GEA 
Sbjct: 4288 PNLRIEWFKNGISLTTGSR----IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAV 4343

Query: 720  ---------------------SLPIVLKIKTGEKEPPQVIEP----------LKSMIVRQ 748
                                 SLP + +++  ++  P+  EP          L ++  ++
Sbjct: 4344 STSSLKIEDRHWLQAESLHPDSLPRIGELEAPKEGRPEAPEPTYETPVFITHLNNIECKE 4403

Query: 749  GESVILSAQV--VGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYT 804
             ++V     V    +P  +I W  N +P++A    KS  D     + L     ++ GVYT
Sbjct: 4404 SDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCALDLTNSYAENSGVYT 4463

Query: 805  LKAENSEGIAETSAVI 820
             KA NS+G A TS  +
Sbjct: 4464 CKATNSKGSATTSGTL 4479



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 83/337 (24%), Positives = 140/337 (41%), Gaps = 35/337 (10%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +EQ +AP FV++       +G  +       G P+P+ITW  Q   ++ S   + +   D
Sbjct: 2190 KEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITW--QKDGVQISSTAERFVGID 2247

Query: 564  NVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
              AT L I  V   DAG + C A+N AG  ++   L VE P      E            
Sbjct: 2248 GGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQRRL-------- 2299

Query: 623  XXXADILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                     +P PT   +P A+         +   L++I   D      GE +    N S
Sbjct: 2300 --------NLPRPTKVIEPGARATSVFKFGFIALDLLSIMGHD-----SGEYMCRVTNAS 2346

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEP 740
               ES      SV++  ++++  +   ++  +N+ E  +       I     + PQ I P
Sbjct: 2347 GVAES--RAILSVVQRPSIEQSSQNPNSLQYINQLEDYSRYQRTESIDEQLNQAPQFIRP 2404

Query: 741  LKSM-IVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKP 794
            L+ +    +G++V   AQV  V +P   + W K+  P+ A   +    +    S+ IL  
Sbjct: 2405 LRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIFNFGYVSLNILH- 2463

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             + +D G YT++A N  G A + + I V   ++  A+
Sbjct: 2464 LRAEDAGTYTVRAVNRIGEAISQSSIRVHSRSQVTAD 2500



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 57/200 (28%), Positives = 85/200 (42%), Gaps = 24/200 (12%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRK-- 1073
            P F +K+Q   V E + A  EVE   E    V W R+     P +N  D +      K  
Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRES---FPIQNSPDLQIHTFSGKSI 6086

Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE---------LPPEIITRLQNQKVNK 1120
            L IR   V D   +SC+  +      C+A + V E          PP  +T +Q+  V  
Sbjct: 6087 LIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVAT 6146

Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178
            G  A F+ ++T    L V W K+G +IQ S   ++  +     L I +   +D+G Y C 
Sbjct: 6147 GQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 6206

Query: 1179 ---EVGNSKCTAILTVEEPS 1195
                 G ++C     V+ PS
Sbjct: 6207 AVNAAGEARCDGDCIVQSPS 6226



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 60/238 (25%), Positives = 97/238 (40%), Gaps = 20/238 (8%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            AP F   L    T +G+ V  EC+++  G P  +I WF     +K    F+  Y+ D VA
Sbjct: 2926 APQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYVA 2985

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASST--------TELIVEAPLSDHGSEMTVXXXXX 618
             L +   +  D+G +TC A+N  G A ++         +LI+E        ++       
Sbjct: 2986 -LDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQKIQYLEDST 3044

Query: 619  XXXXXXXADILEGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIV 675
                    D +  I P F   PK+     EG     EC++  + +P+  + W   G  I 
Sbjct: 3045 RHRRSEFVDEVVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPIT 3104

Query: 676  PDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
                        +H +  V L I ++     G YT  AVN  G     + L+ ++GE+
Sbjct: 3105 VGHRFR-----PIHDFGYVALDIVHLIAEDSGVYTCRAVNLIGSDETQVELQCRSGEQ 3157



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 61/241 (25%), Positives = 95/241 (39%), Gaps = 21/241 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            E    AP+F   L+     +     FEC++     P  ++ W+     +K    F    +
Sbjct: 3188 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 3247

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL-----SDHGSEMTVXXX 616
               VA L I    PEDAGT+TC A NA G A ++   +V         S H + +     
Sbjct: 3248 FGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRLQH 3306

Query: 617  XXXXXXXXXADILEGI---PPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAWLFKG 671
                       + +      P F+   +   V E   +  E RL+ + +P   + WL  G
Sbjct: 3307 LEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNG 3366

Query: 672  EEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIK 728
            + I      +      MH +  V L +  V     GTYT  AVN  G+A  S  ++++ K
Sbjct: 3367 QPIEASNRTTT-----MHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSK 3421

Query: 729  T 729
            T
Sbjct: 3422 T 3422



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 18/234 (7%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            S AP+F   +R     +   V FE ++   G P+  + W R    I+ S      +D   
Sbjct: 3324 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 3383

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGSEMTVXXXXXX 619
            VA L ++ V PED+GT+TC A N  G A ++  LIV++  S      H + M        
Sbjct: 3384 VA-LNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSIQLETQHEAAMHKIHQLED 3442

Query: 620  XXXXXXADILE---GIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673
                   +  E      P F +K      + EG     ECR+   P+P+  + W   G+ 
Sbjct: 3443 HSRYQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKP 3502

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
            +          +       + L I  V     G YT    N  GEA   IVL +
Sbjct: 3503 LSTGHRFRTTYDFGF----AALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNV 3552



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 55/238 (23%), Positives = 92/238 (38%), Gaps = 21/238 (8%)

Query: 505  EQSMAPIFVEKLRPKHT-PDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561
            ++   P FV +++ + T  + +  +FECQ+   G P  ++ WF     +     FQ  YD
Sbjct: 5585 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 5644

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAG--------FASSTTELIVEAPLSDHGSEM-- 611
               VA +    V+PED+G + C A N  G          S    ++ ++ L  H   +  
Sbjct: 5645 FGYVA-MNFGWVYPEDSGEYVCRATNLYGKDETRAIIKVSGKPGIVYDSQLPAHMQSIDR 5703

Query: 612  --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
               +             D      P F  K + Q V+EG       R+   P P + WL 
Sbjct: 5704 IREMEASWQVVPDEVDPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLI 5763

Query: 670  KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
             G  +V      +  +   H     L +   +++  G   V+A N  GE+     LK+
Sbjct: 5764 NGHTVVHGSRYKLTNDGMFH-----LDVPKTRQYDTGKVEVIARNSVGESIATTELKV 5816



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 85/423 (20%), Positives = 164/423 (38%), Gaps = 30/423 (7%)

Query: 508   MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
             + P  VE L       G    FE ++       + WF+    I  ++  Q+  D    + 
Sbjct: 16527 LPPEIVEPLNDVAVTKGENAVFEVELSKGDA-LVKWFKNGKEIVFNERIQLAIDGKKQSL 16585

Query: 568   LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT-VXXXXXXXXXXXXA 626
              +++   PED G ++       G  +S  +L VE PL D    +  +             
Sbjct: 16586 RIVKAK-PEDVGEYSV----QVGEQTSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTV 16640

Query: 627   DILE-GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
              + +  +  T+ KK K    ++  ++ +E  +  +   D +    GE     EN++ + +
Sbjct: 16641 QLSQPDVEVTWCKKGKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTK 16700

Query: 686   SDMHMYCSVLKITN-------VKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQ 736
               +        IT+       VK+  + T+TV         +     K  I   ++  P 
Sbjct: 16701 LCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPT 16760

Query: 737   VIEPLKSMIVRQG------ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
             + E    + +++       + V LS    G P P +TW KN +  ++   + +      T
Sbjct: 16761 IDEQSAKLTIKKDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYT 16820

Query: 791   ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
             I K   ++ E  YT  A N +G AETS  + +++      E     +++    ++    +
Sbjct: 16821 IEK-TTIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVE-----DKYLTQKLRTGSIL 16874

Query: 851   KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
              + A V   P P++TW++       ++++T           +  V  E  SG YK  A+N
Sbjct: 16875 TIPATVRGYPQPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTRE-QSGKYKVTATN 16933

Query: 911   SAG 913
              +G
Sbjct: 16934 ESG 16936



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568
            P+F +  +      G    FE ++ G P+P +TW R+ A +  SQ F+M Y++     +L
Sbjct: 1812 PVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSL 1871

Query: 569  VIREVFPEDAGTFTCVAKNAAGFA 592
            +I ++ P D G +TC A+N  G A
Sbjct: 1872 LINQIGPGDEGEYTCTARNQYGEA 1895



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 32/334 (9%)

Query: 504  EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQ--ITWFRQTAIIKPSQDFQMYY 560
            E Q   P++ + L+ + H  +   +  E  VE    P   I W+    ++     F+M  
Sbjct: 4522 ETQYPPPVWTKPLQAEFHLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMT- 4580

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTT------ELIVEAPLSDHGSEMTV 613
             +    T+ + EV+  D G +TC A N AG A +STT      E I+E+     G+E   
Sbjct: 4581 SEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTTIFCSSKENIIESTQHPKGAEGLE 4640

Query: 614  XXXXXXXXXXXXADILE----GIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD--IA 666
                            E    GIPP F+ +      + EG     E  L+ + +    I 
Sbjct: 4641 QIQDLEDSLRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIE 4700

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            W + G+ +     +       ++ + +V L++   K    GTYT  A N+ G A +   L
Sbjct: 4701 WFYNGKVLEASHRVRT-----IYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNL 4755

Query: 726  K-IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---AL 778
            + +     + P+    I+PL+ +   Q      +   V +P   + W  N K ++    +
Sbjct: 4756 ECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRI 4815

Query: 779  PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             T SD   + +  +   +  D G Y  +A N  G
Sbjct: 4816 KTVSDFG-YVVLDISYLQDHDSGEYVCRAWNKYG 4848



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 24/253 (9%)

Query: 481  TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVE--GYP 537
            T+ LQK L E + K    E  T +EQ   P F E+++     P+G  + F+C+VE  G P
Sbjct: 5286 TESLQK-LEETMHKRE--ELVTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDP 5342

Query: 538  RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
              +I WF    ++          D   +A L +  ++  D+G +TC A N  G A+++ +
Sbjct: 5343 TMRIEWFYNGHVMATGSRVHQLNDFGFIA-LDVDYIYARDSGEYTCRATNKWGTATTSAK 5401

Query: 598  --------LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYVDE 647
                    ++ E+ L + G                   ++E +  PP F+ +  +  VDE
Sbjct: 5402 VTCKGKHNIVYESQLPE-GMTSEKLKELERGRIPEAPKVVEEVFGPPKFTTQITSVTVDE 5460

Query: 648  GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
               +  EC++    +P   + W   G+ + P  +      +   M    L I  V     
Sbjct: 5461 AEAVRFECQVEPKTDPSLRVEWYRNGKPL-PSGH---RYRNIFDMGFVSLDILYVYGEDS 5516

Query: 706  GTYTVVAVNREGE 718
            G Y   A+N  GE
Sbjct: 5517 GEYVCRAINNYGE 5529



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 83/378 (21%), Positives = 146/378 (38%), Gaps = 40/378 (10%)

Query: 370  ELPKEDVPEQYTI-TPRKSSAQKIDE---IVDEVTIKKRLNP---FEIFYTPVEVRCGDT 422
            E+  +  P+Q  + T    S  K+ E   ++ E  ++ R +P    E F   + +  G  
Sbjct: 4247 EMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSR 4306

Query: 423  VFAVYSYVAETDEAINL-VEGERLYILDTSNQDWWYVQKHLT--EEKGWVPAQYLMDENN 479
            + + + +   T     L  +   +Y    +NQ    V       E++ W+ A+ L  ++ 
Sbjct: 4307 IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDRHWLQAESLHPDSL 4366

Query: 480  YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY--P 537
                   +L    +  P   +PT E     P+F+  L      +   V+FEC VE    P
Sbjct: 4367 PRI---GELEAPKEGRPEAPEPTYE----TPVFITHLNNIECKESDNVRFECNVEPARDP 4419

Query: 538  RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--- 594
               I WF     ++ +  F+  YD    A L +   + E++G +TC A N+ G A++   
Sbjct: 4420 TMSIEWFYNGQPLQAAAKFKSIYDFGYCA-LDLTNSYAENSGVYTCKATNSKGSATTSGT 4478

Query: 595  -------TTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
                   T  L  + P  + G E    T                 +  PP ++K  +A++
Sbjct: 4479 LKCTGGKTMFLDTQHPQGEAGLEAVQETEEELANRYTSKTTKPETQYPPPVWTKPLQAEF 4538

Query: 645  -VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
             + E   I LE  +    +P+  I W F G+ +       +  E         + +  V 
Sbjct: 4539 HLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMTSEFGF----VTMDMIEVY 4594

Query: 702  KFQEGTYTVVAVNREGEA 719
               +G YT  A N+ GEA
Sbjct: 4595 ARDQGIYTCKAYNKAGEA 4612



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 58/274 (21%), Positives = 106/274 (38%), Gaps = 23/274 (8%)

Query: 1464 ASETTE--YYKVIKETKIQSPT--VEKPLKNITTEP-----NEDIELTCIFGGVPQPKVT 1514
            A+ETTE  +   I+E  +Q P    + P+     +P     NE  +    F G P P V 
Sbjct: 6003 ATETTEVEHKGTIQERVVQGPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVK 6062

Query: 1515 WYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            WYR+   ++ +      T+  +               + C+A N  G  + S  + ++++
Sbjct: 6063 WYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEER 6122

Query: 1571 P------VITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
                   +   S     Q   V    L    A + G  P +V W KNG K++   ++ + 
Sbjct: 6123 RRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKML 6182

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
             ++    + I E     S +Y   A N AG +  +    +   PSKPE P          
Sbjct: 6183 EEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDGDC-IVQSPSKPEKPTTPGSEKAPH 6241

Query: 1683 VTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            +  + K   +++G   + +  ++       RW++
Sbjct: 6242 IVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMR 6275



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 63/246 (25%), Positives = 103/246 (41%), Gaps = 21/246 (8%)

Query: 490  EKIDKLPVFE---KPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQITW 543
            EKI +L  +    KP  EE+   PIF+  L   +H  +G     EC+VE    P  +I W
Sbjct: 3702 EKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPINDPNLKIEW 3761

Query: 544  FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--- 600
            F     +     ++  +D   VA L I  V+ ED GT+ C A N  G A +T  + V   
Sbjct: 3762 FCNGKQLPTGHRYRTTHDFGYVA-LDILYVYGEDTGTYICKATNQLGEAVNTCNVRVLNR 3820

Query: 601  EAPLSD--HGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK-AQYVDEGSDILLEC 655
             + + D  H   +               ++ +    PP F+ + + +  + EG     E 
Sbjct: 3821 RSMILDTQHPDALEKIQKLESKVPNARTEVGDAPISPPHFTAELRGSTEIYEGQTAHFEA 3880

Query: 656  RLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
            ++  + +P+  I +   G+ +       +  +     Y S L IT+      G Y+V AV
Sbjct: 3881 QVAPVHDPNLRIEFYHNGKPLPSASRFHITFDFG---YVS-LDITHAVAEDAGEYSVRAV 3936

Query: 714  NREGEA 719
            N  G+A
Sbjct: 3937 NALGQA 3942



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+FV KL P+   +G   +F  +V G+PRP++ W      +     +++   +D +  L 
Sbjct: 5728 PVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKL--TNDGMFHLD 5785

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
            + +    D G    +A+N+ G + +TTEL V A   D+
Sbjct: 5786 VPKTRQYDTGKVEVIARNSVGESIATTELKVVARSDDY 5823



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 83/398 (20%), Positives = 148/398 (37%), Gaps = 46/398 (11%)

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
            TE     PLF    ++   +E         VT  P P++ W+++   I  +      FD 
Sbjct: 218  TELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDK 277

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-----DVEKV--TFVKHLQKSY 938
                LVI    +  DS  + C ASN  G     A +++     +V+ V    ++ LQ   
Sbjct: 278  GICRLVIEETFA-ADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGK 336

Query: 939  ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
             T EG +    C  +     + +W+ N K I       I                 D  V
Sbjct: 337  AT-EGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 395

Query: 997  IKCIVKD----QETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047
              C   +    +  S  L+V+      +P F   L +   +      LE  +      +V
Sbjct: 396  YTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEV 455

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY-------------SC----- 1089
             W  +G+  +P+ +KY++   G +  L I     +D G Y             SC     
Sbjct: 456  YWLHNGKPFQPRDSKYEY---GRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVK 511

Query: 1090 -ILRDESCTAEVT--VVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSE 1145
              L +E+  +E+   +  + P +   L++  + +G     + + + + +  V W+ +   
Sbjct: 512  GRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERP 571

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ++ S  +QL   G +  L I +   +DAG Y     NS
Sbjct: 572  VKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINS 609



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 15/193 (7%)

Query: 1091 LRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK-GDA--LVRWFKDGSEI 1146
            LR +    E   + +PP   T   N   + +G  A FE  L   GD   ++ WF +G  +
Sbjct: 4649 LRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIEWFYNGKVL 4708

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT-----VEEP---SINF 1198
            + S+ ++         L++    ++D G Y+C   N   TA ++     V++P      F
Sbjct: 4709 EASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVDKPRGQKPRF 4768

Query: 1199 TLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
            T  +     +     A+     + + D  L V WY    ++  + +   +SD     L I
Sbjct: 4769 TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDI 4828

Query: 1256 RKCTEDDQCEYTC 1268
                + D  EY C
Sbjct: 4829 SYLQDHDSGEYVC 4841



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            GD ++    + G P P V W+K+G  ++ + +Y  T  +    + I+E   + S++++  
Sbjct: 239  GDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCR 298

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE--GPVIMREISRESVT 1684
            ASN  GT     TL V +  ++ +   P I+R +     T
Sbjct: 299  ASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKAT 338



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 8/175 (4%)

Query: 746  VRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDE 800
            + +GE     A +  VG+    I W  N K ++A   + T     T ++ +L  K ++D 
Sbjct: 4677 IGEGELAHFEANLIPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTK-IEDT 4735

Query: 801  GVYTLKAENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            G YT +A N  G AE S  +  V++P  +       I   + +   +    +       +
Sbjct: 4736 GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVND 4795

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            P   + WY N +++  S  I    D   + L I+ +    DSG+Y C A N  G+
Sbjct: 4796 PDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDH-DSGEYVCRAWNKYGE 4849



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%)

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQ 881
            E  E   E P+FI     I  KE   ++    V   R+P  SI W+ N + +  +     
Sbjct: 4381 EAPEPTYETPVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKS 4440

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +D     L +TN  +E +SG Y C A+NS G ++    +     K  F+
Sbjct: 4441 IYDFGYCALDLTNSYAE-NSGVYTCKATNSKGSATTSGTLKCTGGKTMFL 4489



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 7/179 (3%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
            +P    PL     +   D+ +  I+ G P P++   ++G +L     T  +   NR    
Sbjct: 976  APRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIE 1035

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAV 1595
                       Y   A N  G+  ++  + +++     +    ++ Q  K G++  +   
Sbjct: 1036 LKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVE 1095

Query: 1596 IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            + G+P P V W K+   L++    E+ +  +  +  + I++ + + S KY + A+N  G
Sbjct: 1096 VTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGG 1154



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            ST  L V+   FPP      +    K+G  +T+ V+    P+P   W+ + K +K    +
Sbjct: 1060 STADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGIS 1119

Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            +  +     S  L I+K + TD+G Y +R  N  G A    +  IL+ PSP
Sbjct: 1120 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILE-PSP 1169



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 10/176 (5%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D E+ E  +   +  +      +V W  +G  ++   +            L 
Sbjct: 2097 PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 2156

Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127
            I N +  D G   C+ R+++      A++ V+E    + P+ + R     V +G   T  
Sbjct: 2157 ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 2216

Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
               +      + W KDG +I  +    + IDG    L+I     +DAG Y C   N
Sbjct: 2217 ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQN 2272



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 11/228 (4%)

Query: 201   IDNEVPEKINVPDDKETSQTP------TSFNKRSKLTPIKIERKEM-EVSTPQHAETVDG 253
             I  E+P+ +  P  +   + P      +SF +  KLTP+KIE+ E  +    + +  V+ 
Sbjct: 11502 IHQEIPKTVLQPYQRTEMELPQRARRDSSFKQPVKLTPMKIEKVEFKKPKMVEISSVVEF 11561

Query: 254   PQFXXXXX-XXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGI 312
             PQ                + +       +LKS I+++  + P     +++ + + ++ G 
Sbjct: 11562 PQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIRFV-PYAPYCFPYVVTELETNREVGE 11620

Query: 313   LSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372
             LSRN+ EA +V K      K    EK ELE+      +   S K   E++  K    +  
Sbjct: 11621 LSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLGAYESDHSDKSNKELLHPKYKRGKKE 11680

Query: 373   KEDVP-EQYTITPRKSSAQKIDEIVDEVTIKK-RLNPFEIFYTPVEVR 418
             K + P E   +   K    + +E  +EV +K  +L+  EI    + VR
Sbjct: 11681 KIETPDESRKLKFGKGKVPQNEEASEEVNLKPVKLDIAEIEDAEMPVR 11728



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 62/270 (22%), Positives = 100/270 (37%), Gaps = 23/270 (8%)

Query: 499  EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555
            ++P +      P+F + L+      +  T  FE ++   G P  ++ W+R   II+ S  
Sbjct: 3981 QEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSR 4040

Query: 556  FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615
                +D   V+ L I  +  ED G + C A N  G A +T  + V   +S+   +M    
Sbjct: 4041 ITKQHDFGFVS-LDISHIRKEDEGVYMCRAVNPLGEAVTTASMRV---VSEASIQMDTQH 4096

Query: 616  XXXXXXXXXXADILEGIPP----TFSKKPKAQYVD------EGSDILLECRLVAIPEPDI 665
                         L   P      F K    Q +       EG+    E R+V + +P +
Sbjct: 4097 PDSISRIHQLEKPLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSL 4156

Query: 666  --AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
               W   G E+     +   + +        L IT V     G Y   A N  GEA    
Sbjct: 4157 KFEWFINGVEL----QMGSRLRTTHDFGFVTLDITAVVPEDAGVYMCRAYNAAGEAVSST 4212

Query: 724  VLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             +K+KT      Q + P     +R  E+ +
Sbjct: 4213 AMKVKTKSNIDGQPLIPESWEAIRLKEAAM 4242



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 5/104 (4%)

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNNEIISPSETITQNFD 884
            EE   PP F  +   +TV E   ++   +V     PS  + WYRN + +         FD
Sbjct: 5441 EEVFGPPKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFD 5500

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
               + L I  V  E DSG+Y C A N+ G+     R T+  +K+
Sbjct: 5501 MGFVSLDILYVYGE-DSGEYVCRAINNYGEDR--TRATVSCKKL 5541



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 5/105 (4%)

Query: 815  ETSAVITVEEP-TEENAEPPLFINRFQEIT-VKEKGTIKLVARV--TRNPVPSITWYRNN 870
            E++A    +EP T    + P+F    Q I  + E  T    AR+    +P   + WYRN 
Sbjct: 3973 ESTAPHQRQEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNE 4032

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            +II  S  IT+  D   + L I+++  E D G Y C A N  G++
Sbjct: 4033 KIIEDSSRITKQHDFGFVSLDISHIRKE-DEGVYMCRAVNPLGEA 4076



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G +  + A+ +G P PE+   KNG +L  D    I+ K     I +K++    + +Y + 
Sbjct: 991  GADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVT 1050

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIE 1686
            ASNT G S+    L V      P  G  +  ++S+  E +T+E
Sbjct: 1051 ASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME 1093



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 22/165 (13%)

Query: 1599  IPPPEVIWYKNGNKLEND--KEYNITTKEKT----SVIRIKELKRSHSSKYTIEASNTAG 1652
             +P P+++W  NG  ++ +  K   I T+       SV+ I ++K+S    Y + A+N  G
Sbjct: 16083 VPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKSQEGTYEVIATNREG 16142

Query: 1653  TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
              + + +TLKV  + +  E P I+  + R  V       + +G   +    I  + P    
Sbjct: 16143 EARLPITLKV--RTTDKEAPQILEPL-RNMV-------IREGESVVLSTQIVGNPPPKVT 16192

Query: 1713  W------IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             W      +K A  D+D+ T  +    ++ +  + V A NP+G  E
Sbjct: 16193 WYKDGKPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNPLGSVE 16237



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            + PT   + +AP F   L  K    G+ V  E   +G+P P+I   +    +      ++
Sbjct: 966  DSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRI 1025

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
              +  N  T+ +++V   DAG +   A N  G ++ST +L+V+
Sbjct: 1026 -SNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVK 1067



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 37/157 (23%), Positives = 67/157 (42%), Gaps = 13/157 (8%)

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            + +  ++  + W  +G++++           G +  L +  T + D G Y+C   ++  T
Sbjct: 4690 IPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVA-LEVLGTKIEDTGTYTCRATNKHGT 4748

Query: 1098 AEVTV----VELP----PEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSE 1145
            AE++     V+ P    P   + +Q  + +  G  A FE   I +   D  V W+ +G  
Sbjct: 4749 AEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 4808

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            ++ SN I+   D     L I      D+GEY C   N
Sbjct: 4809 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWN 4845



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 53/228 (23%), Positives = 86/228 (37%), Gaps = 17/228 (7%)

Query: 507  SMAPIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQ----ITWFRQTAIIKPSQDFQMYYD 561
            + AP F+  L+      +G    FE +VE  P+      I W+     I  +   Q YYD
Sbjct: 2669 TQAPRFLGPLKGTTKILEGQRAHFEARVE--PQSDLGLVIEWYHNGRSITAANRIQTYYD 2726

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
               VA L I +V  EDAG +  VA+N    +S  T  +       +     +        
Sbjct: 2727 FGYVA-LDISQVRAEDAGVYLVVARNKLARSSIDTSSMHRGL---YEKTQNLENKPFVEP 2782

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDEN 679
                 +I +  P   +     + + +G +I LECRL  + +P   + W   G  +     
Sbjct: 2783 QYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSR 2842

Query: 680  ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
                 +    +   ++K T       G YTV A N  G A     +++
Sbjct: 2843 FRTYYDFGF-VALDIIKATAA---DSGEYTVRATNHLGTAHTSACVRV 2886



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 827  EENAEPPLFINRFQE-ITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNF 883
            +E   PP F    ++ + V E G I    RV    +P   I W+ N  +++    + Q  
Sbjct: 5306 DEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVHQLN 5365

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            D   I L +  + +  DSG+Y C A+N  G ++  A+VT
Sbjct: 5366 DFGFIALDVDYIYAR-DSGEYTCRATNKWGTATTSAKVT 5403



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 17/212 (8%)

Query: 44    LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVK----LPKFQLKSRIK 99
             L  ++IE++E  KP+  E  +V +F             QE    K        +LKS I+
Sbjct: 11537 LTPMKIEKVEFKKPKMVEISSVVEFPQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIR 11596

Query: 100   FIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLF 159
             F+  + P     +VT L + ++ GELSRNV EA                E+  LE++DL 
Sbjct: 11597 FV-PYAPYCFPYVVTELETNREVGELSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLG 11655

Query: 160   DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
               + D S  D S        +    PK     ++ I    E       K  VP ++E S+
Sbjct: 11656 AYESDHS--DKS-------NKELLHPKYKRGKKEKIETPDESRKLKFGKGKVPQNEEASE 11706

Query: 220   TPTSFNKRSKLTPIKIERKEMEVSTPQHAETV 251
                   K  KL   +IE  EM V T Q  E V
Sbjct: 11707 EVNL--KPVKLDIAEIEDAEMPVRT-QEEEVV 11735



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 1/103 (0%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATL 568
            P+F  +L+ + +  G  +  E +V G P P +TW +    +K +           N   L
Sbjct: 1073 PVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL 1132

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
            +I +    D+G +   A NA G A S  +  +  P  +   E+
Sbjct: 1133 IIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEV 1175



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F +  K     +G + L E RL   P+P + W  KG  ++  +   ++  ++     
Sbjct: 1811 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSY-NEATGDV 1869

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S+L I  +    EG YT  A N+ GEA   + ++ +       Q I+ L+  I   G S
Sbjct: 1870 SLL-INQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPIQNLEKNIYSNGYS 1927



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 21/78 (26%), Positives = 35/78 (44%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
            IS +    K   G + + TA +   P P + W+ NG +L   ++Y I+     + +R+K 
Sbjct: 1982 ISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRVKN 2041

Query: 1635 LKRSHSSKYTIEASNTAG 1652
                    YT+ A N  G
Sbjct: 2042 ATARDGGHYTLLAENLQG 2059



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 6/120 (5%)

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880
            EE  E   + P+F    + + +KE        R+    +P   + WY NN  +      T
Sbjct: 3184 EEIDESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFT 3243

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
            +  +   + L I +   E D+G Y C A N+ G++   A   +  +K  +   L+  +ET
Sbjct: 3244 ETNNFGFVALDIMSTLPE-DAGTYTCRAYNAVGEAITSAVAVVHTKKSIY---LESQHET 3299



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 14/160 (8%)

Query: 1461 ISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWY 1516
            I    +T+ + +   E +  +  P   +PL+N        + L  T I    P  KV WY
Sbjct: 3571 IQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWY 3630

Query: 1517 RDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             +G+ ++T    K TY+                  Y C A N  GE  T+C V +     
Sbjct: 3631 CNGRPIQTGHRFKTTYDFGFVALDILYAHAEDTGTYMCKAKNAIGEAVTTCAVNVTANKT 3690

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            + +   D ++  K+    L T      PPP+ +  + G K
Sbjct: 3691 LDLDTLDAQRLEKI--RQLETYA----PPPKPVVEEKGQK 3724



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 59/249 (23%), Positives = 103/249 (41%), Gaps = 22/249 (8%)

Query: 164   DESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK-ETSQTPT 222
             +ES  D   P   ++ EA  E    + SE+P  K  E++ E  EK    DDK ET++   
Sbjct: 13436 EESIIDEPIPEDYVVTEAAEE----KPSEEPTFKVEELETEAVEKEVTDDDKGETTKQSV 13491

Query: 223   SFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQL 282
             +  K  KL   K E  E+ V T    +T D P++              E      P+ + 
Sbjct: 13492 TKRKIKKLVGPKEEIIEI-VET----KTGDTPEYEVIVTTEEVQEKSKEA-----PEEKK 13541

Query: 283   KSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL- 341
                ++     P + ++    Y+  + +  I    +++  K+     V  K   ++K +  
Sbjct: 13542 AKTVRKAKKIPKDDLQ---DYIQKLIEQDIPKTELEKYEKIDLDEPVKMKRKPIKKVKQS 13598

Query: 342   -EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVT 400
              EQP    E+ +E K  E +I +  +   + PK  V  +  I P K   +  + +V E T
Sbjct: 13599 EEQPKEETEEPIEDKPVE-KISEYSEVDSDEPKLTVAVKEFI-PEKPEEKPFEIVVLEET 13656

Query: 401   IKKRLNPFE 409
             ++ +  P E
Sbjct: 13657 VESKREPDE 13665



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIE 889
            PP+F   F+     + G      R+  NP P +TW R    +  S+    +++    ++ 
Sbjct: 1811 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVS 1870

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKS 915
            L+I  +    D G+Y C A N  G++
Sbjct: 1871 LLINQIGPG-DEGEYTCTARNQYGEA 1895



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 8/115 (6%)

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFG--GVPQPKVTWYRDGKKLKTA---KATYE- 1530
            T +Q+P   + L NI T    ++ L C     G P  ++ W+ +GK +KT    +  YE 
Sbjct: 2922 TIMQAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEF 2981

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQK 1583
            +                Y C A N  GE  TSC V I  K   ++   NE   QK
Sbjct: 2982 DYVALDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQK 3036



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 12/129 (9%)

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGD 785
            G+  PP   +  K+    QG + +   ++ GNP+P +TW +   P+    K   + ++  
Sbjct: 1807 GDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEAT 1866

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------EPTEENAEPPLFINR 838
                 ++      DEG YT  A N  G A  S  I  E       +P  +N E  ++ N 
Sbjct: 1867 GDVSLLINQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPI-QNLEKNIYSNG 1925

Query: 839  FQEITVKEK 847
            +   +++E+
Sbjct: 1926 YSYTSIEEE 1934



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYNITTKE 1625
            QQ PV T   +   + H+ G   L+ A +E    P   + W+KNG  L        T   
Sbjct: 4255 QQAPVFTTHLQSYDKLHE-GQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDF 4313

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
                + I  L+   S+ YT +A+N  G +    +LK+ D+
Sbjct: 4314 GLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDR 4353



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 64/298 (21%), Positives = 114/298 (38%), Gaps = 39/298 (13%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P+I  + ++ K+ +G+ A F   + +     + WF +G  +  S   +++       L++
Sbjct: 1980 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRV 2039

Query: 1166 YDCDLDDAGEYSCEVGNSK-C---TAILTVE-------EPS-INFTLRLPEF--ILVPAN 1211
             +    D G Y+    N + C   +A+L VE       EP  ++      E    L PA 
Sbjct: 2040 KNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPPAF 2099

Query: 1212 TDAYLTVEIPDETL-------------DVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRK 1257
              A+   EI +  +             +V W    + V +D     L+++    +L+I  
Sbjct: 2100 VKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITN 2159

Query: 1258 CTEDDQCEYTC--------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             T  D     C        V ++A+     K +VV   P+ V       ++ G  +T+  
Sbjct: 2160 VTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVA--PQFVQRFSTMTVREGEPITMSA 2217

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            +    PQP   W  +   I         ID  +  L I +V   DAG Y+   +N  G
Sbjct: 2218 NAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAG 2275



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 7/102 (6%)

Query: 732  KEPPQVIEPLKS-MIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGD 785
            K  P  + PL     +  G+++ L  ++  +G+P   + W  N +PV       T  D  
Sbjct: 2791 KSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSRFRTYYDFG 2850

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
              ++ I+K     D G YT++A N  G A TSA + V + T+
Sbjct: 2851 FVALDIIKATAA-DSGEYTVRATNHLGTAHTSACVRVIDHTD 2891



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 7/124 (5%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP--KVTWYRD 1518
            + D S  T   ++ + TK Q+P     LKN+  + N+     C    V  P  +V WY +
Sbjct: 3174 LEDRSRYTRREEIDESTK-QAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHN 3232

Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
               LK+     E                     Y C A+N  GE  TS V  +  K  I 
Sbjct: 3233 NLPLKSGSRFTETNNFGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIY 3292

Query: 1575 ISNE 1578
            + ++
Sbjct: 3293 LESQ 3296



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 3/96 (3%)

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            ++ P+F    +++ V E   +   AR+    +P  ++ W RN + I  S   T   D   
Sbjct: 3324 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 3383

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + L +  V+ E DSG Y C A N  G++   A + +
Sbjct: 3384 VALNMKYVNPE-DSGTYTCRAVNELGQAVTSASLIV 3418



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%)

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
            I+ + DF     D++ L+   + E     W + GE     +   +   RG +    ++  
Sbjct: 4815 IKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYGEDFT--RTTLNCGGRGGVFYDSLQPD 4872

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK---GDA 1135
            S+    E  C    ++ T+   V E PP+ IT++ +  K+ +G  A FE  LT     D 
Sbjct: 4873 SLQRIRELECPQGQQADTSAPLVAE-PPKFITQIVDVTKLVEGQSAHFEARLTPITDPDL 4931

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +V W+ +G ++   +  +   D     L I  C  +++G Y     N
Sbjct: 4932 VVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARN 4978



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 10/108 (9%)

Query: 494   KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
             +L + +KP  E +       +KLR      GS +     V GYP+P +TW ++T   K +
Sbjct: 16848 RLKLQQKPVLEVEDK--YLTQKLRT-----GSILTIPATVRGYPQPTVTWHKETIEQKTT 16900

Query: 554   QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELI 599
             +   +    +  +T  +++V  E +G +   A N +G  +   T ++I
Sbjct: 16901 KSVTI-ETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVI 16947



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            +P  +    P+F+++ +  TV+E    +   RVT +P P + W  N   +          
Sbjct: 5719 DPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKLTN 5778

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            DG    L +     + D+G  + +A NS G+S
Sbjct: 5779 DG-MFHLDVPKT-RQYDTGKVEVIARNSVGES 5808



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
            E PQ   PL++  V +G  V L A +  V +P   + W  N +P++      T  D    
Sbjct: 3592 ERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFV 3651

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++ IL     +D G Y  KA+N+ G A T+  + V
Sbjct: 3652 ALDILYAH-AEDTGTYMCKAKNAIGEAVTTCAVNV 3685



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 1106 PPEIITRLQNQ-KVNKGNKATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161
            PP+  T +QNQ  + +   A FE  L   GD+ +R  W KDG  ++ S+ I    +    
Sbjct: 2537 PPQFKTPIQNQLDLREHAHAHFEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYV 2596

Query: 1162 KLKIYDCDLDDAGEYSCEVGNS 1183
             L I    + DAG Y+C   N+
Sbjct: 2597 ALTIKQLTIYDAGTYTCRAYNA 2618



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%)

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNN 870
            + +TS      +  + +AE P F    +   V E   + L A +    +P   + WY N 
Sbjct: 3574 LEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNG 3633

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
              I         +D   + L I    +E D+G Y C A N+ G++     V +   K
Sbjct: 3634 RPIQTGHRFKTTYDFGFVALDILYAHAE-DTGTYMCKAKNAIGEAVTTCAVNVTANK 3689



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 6/130 (4%)

Query: 815  ETSAVITVEEPTEEN-AEPPLFINRFQEI-TVKEKGTIKLVARVTR--NPVPSITWYRNN 870
            E S V T EE TEE   + P+F    + I  ++E       AR+T   +P   + WY N 
Sbjct: 5018 EYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYWNG 5077

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VT 929
              +          D   + L I+ V  E DSG+Y C A N  G++   A + I  ++ + 
Sbjct: 5078 RPLKAGSRFRTFCDFGFVILEISPVYPE-DSGEYSCRAINEYGEAVTTATMKIQGKRSII 5136

Query: 930  FVKHLQKSYE 939
                L K  E
Sbjct: 5137 MESQLPKGME 5146



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 81/389 (20%), Positives = 135/389 (34%), Gaps = 37/389 (9%)

Query: 1272  DAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
             +A+    LKV   +   P+I++  R   I+ G  V L       P P   W  + K +K 
Sbjct: 16143 EARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKN 16202

Query: 1331  CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
              K      D    +LT+   + ++ G Y ++  N  G  +   N+TI +      +P + 
Sbjct: 16203 AKS-----DKDLHTLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLF 16257

Query: 1391  EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
                    N+    P+       +   V    +   +W+           IQ +    +  
Sbjct: 16258 VERFEEQNV----PQK--GEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIE 16311

Query: 1451  FRAYAVN-EVDISD--------ASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIE 1500
                   N E D  D          +T+   +VI E  +   T  K L K IT E  + + 
Sbjct: 16312 LIIKDANPETDSGDYKCIASNPIGKTSHGARVIVE--VDEVTFTKKLKKTITIEEVQSLT 16369

Query: 1501  LTCIFGGVPQPKVTWYRDGKKLK--TAKATYEN--RXXXXXXXXXXXXXXXYKCIAFNDH 1556
             L C    V   K  W+ +GK+L     +   E+                  Y C      
Sbjct: 16370 LECETSHVVTTK--WFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKKQE 16427

Query: 1557  GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-EN 1615
              +   S V  +Q+KP      ED +   K   +  +  V       EV WYK+G K+   
Sbjct: 16428 TQ---STVEVLQRKPDFIKVLEDYEVTEK---DTAILDVELTTEATEVTWYKDGEKITPE 16481

Query: 1616  DKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             +K        K   + I+++      +YT
Sbjct: 16482 NKNVEFIKDGKARRLVIRDVTIHDEGQYT 16510



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 35/193 (18%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            C   G P P+V W  +G++++   +                          +C+A N  G
Sbjct: 2118 CRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITNVTRLDAGAVQCLARNKAG 2177

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            EV     + + +K  + ++ + +++   +    G+   ++A   G P P + W K+G ++
Sbjct: 2178 EVAIEAQLNVLEKEQV-VAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQI 2236

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
             +  E  +      + + I  +  + +  Y   A N AG+++    L V     +P    
Sbjct: 2237 SSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQ 2296

Query: 1674 IMREISRESVTIE 1686
                + R +  IE
Sbjct: 2297 RRLNLPRPTKVIE 2309



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
            + PQ    L ++   +G +V L    Q VG+P   I W  N KPVK         + D  
Sbjct: 2925 QAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYV 2984

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++ +L    + D GVYT +A N  G A TS  + +
Sbjct: 2985 ALDLLGCYAI-DSGVYTCQARNQLGEAVTSCSVRI 3018



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 11/128 (8%)

Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD---ALVRWFK 1141
            EYS +   E  T E       P     L+N + + +G  A FE  +T  D     V W+ 
Sbjct: 5018 EYSMVRTREETTEETK--GKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYW 5075

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI 1196
            +G  ++  +  +   D     L+I     +D+GEYSC    E G +  TA + ++ + SI
Sbjct: 5076 NGRPLKAGSRFRTFCDFGFVILEISPVYPEDSGEYSCRAINEYGEAVTTATMKIQGKRSI 5135

Query: 1197 NFTLRLPE 1204
                +LP+
Sbjct: 5136 IMESQLPK 5143



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 27/257 (10%)

Query: 159   FDSQEDESKPDVSQPPQN--IIEEAKSE---PKLIEESEQP-IAKTSEIDNEVPEKINVP 212
             F +++ E KP V + P+    I++ K +   P+++EE E   + K      EV E+  + 
Sbjct: 15329 FATKDSEKKPTVEELPEEQVTIQKKKKKAPVPEVVEEPEAEFLVKPKTPVQEVTEEAKIT 15388

Query: 213   DDKE-TSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271
               K+   +   +   +  +T       E++    +  E  +                  E
Sbjct: 15389 KSKKPVKEEEAAAELKVTITEEIPTEPEVQEIIEEIEEIEEEKPAEYVIEVKESQPEAVE 15448

Query: 272   TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331
                V LPK + K+ I        E  +  I+    +K     S  ++E AK+ K+   P 
Sbjct: 15449 DKEVSLPKKKPKAPIV-------EEPEAEITLKPKVK-----SEEVQEEAKIVKKK--PK 15494

Query: 332   KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYT----ITPRKS 387
             K+ +V   + E  +   E++V     E E+I+E + +++ PKE  PE       +  +K 
Sbjct: 15495 KIDEVAVAD-ELTVKVEEEVVPEPIVEEEVIEEFE-IKKKPKEPEPEDIVDAAIVKLKKP 15552

Query: 388   SAQKIDEIVDEVTIKKR 404
                  DE+V EVT+K +
Sbjct: 15553 EPVDADEVVAEVTLKPK 15569



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 7/98 (7%)

Query: 501   PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
             PT +EQS A + ++K           V   C   G P P++TW +   + + S+  +   
Sbjct: 16759 PTIDEQS-AKLTIKKDVVSELD--KEVTLSCVFGGIPEPKVTWKKNGQVFE-SRSIRY-- 16812

Query: 561   DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
              ++ VA   I +   E   T+TCVA N  G A ++  L
Sbjct: 16813 -ENRVAKYTIEKTTIETEATYTCVATNEKGSAETSCRL 16849



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 36/169 (21%), Positives = 60/169 (35%), Gaps = 11/169 (6%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------LDAKSTTKLK 1280
            V W+K    I+    +    D     L+I +    D   ++C         D  +T  ++
Sbjct: 256  VEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVR 315

Query: 1281 ---VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
                EV   PP+I+ + +  +   GS           P P  +W  N K I        S
Sbjct: 316  ENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVIS 375

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPP 1384
             ++  A+L  ++V   D  +Y     N  G  H    + V  L+    P
Sbjct: 376  YNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELP 424



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 18/195 (9%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            PP  I  L+ +   +   A  E  + + + L   +WF     I+ SN +++     K  L
Sbjct: 8387 PPRFIQPLEPKYFGEHEVAIIEA-IVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTL 8445

Query: 1164 KIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINF-TLRLPEFILVPANT---- 1212
             I +      G ++C   N      S  T  L  +E +  F + R  E ++ P       
Sbjct: 8446 LIENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGE 8505

Query: 1213 DAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVL 1270
               LT ++  + T  V WY     I + ++ T+  D++    L I +   +++ +Y CV 
Sbjct: 8506 ALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVA 8565

Query: 1271 LD--AKSTTKLKVEV 1283
             +   KS +K  V++
Sbjct: 8566 TNKIGKSVSKTNVKI 8580



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/86 (24%), Positives = 39/86 (45%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + +G+DV++   Y  FP P  +   N   + +  HT+ S      ++ +K+V   DAG Y
Sbjct: 988  VDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRY 1047

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384
             +   N  G +    ++ +     PP
Sbjct: 1048 AVTASNTVGQSTSTADLVVKKTIFPP 1073



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 5/114 (4%)

Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALV 1137
            +H   ++S   R E    E TV   P  +   +    + +G  A +E  +      +  V
Sbjct: 3437 IHQLEDHSRYQRREE--EEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKV 3494

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
             WF +G  +   +  + T D     L I     +D+GEY+C V N+   AI ++
Sbjct: 3495 EWFHNGKPLSTGHRFRTTYDFGFAALDILTVYAEDSGEYTCRVTNNLGEAINSI 3548



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%)

Query: 804  TLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEIT-VKEKGTIKLVARVT--RN 859
            TL A+  E I +        +P  EE  + P+F+     +  +KE     L  RV    +
Sbjct: 3695 TLDAQRLEKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPIND 3754

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P   I W+ N + +          D   + L I  V  E D+G Y C A+N  G++ +  
Sbjct: 3755 PNLKIEWFCNGKQLPTGHRYRTTHDFGYVALDILYVYGE-DTGTYICKATNQLGEAVNTC 3813

Query: 920  RVTI 923
             V +
Sbjct: 3814 NVRV 3817



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 1107 PEIITRLQNQKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            P+    L+N KVN+G     E   I +      V W+ +G  IQ  +  + T D     L
Sbjct: 3594 PQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFVAL 3653

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILT 1190
             I     +D G Y C+  N+   A+ T
Sbjct: 3654 DILYAHAEDTGTYMCKAKNAIGEAVTT 3680



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 9/121 (7%)

Query: 730  GEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKSD 783
            G ++ P   +PL+++  + + ++    A++  VG+P   + W +N K ++    +  + D
Sbjct: 3987 GTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHD 4046

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQE 841
                S+ I   +K +DEGVY  +A N  G A T+A + V  E   + + + P  I+R  +
Sbjct: 4047 FGFVSLDISHIRK-EDEGVYMCRAVNPLGEAVTTASMRVVSEASIQMDTQHPDSISRIHQ 4105

Query: 842  I 842
            +
Sbjct: 4106 L 4106



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 64/274 (23%), Positives = 108/274 (39%), Gaps = 20/274 (7%)

Query: 162  QEDESKPDVSQPPQNIIEEAKS---EPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218
            +ED  KP V   PQ ++ E K    +P+ + E +  +A T   +  V    + P  +E  
Sbjct: 7116 EEDLIKP-VQPEPQPVLWERKKKKPQPQDVIEEKLDVAPTKTYEKAVDVLPDEPKVEEKP 7174

Query: 219  QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278
            + P  + +  K  P K E  E EV    H + VD                       K P
Sbjct: 7175 E-PVLWQRGKKKIP-KSEPTE-EV----HPDEVDAQIETVVKEDEMIVEEKRRIKKTKRP 7227

Query: 279  KFQLKSRIKYITSWPPESIKP-----LISYMGSIKQNGILSRNIKEAAKVK-KQVFVPPK 332
            K   +   +     P E I P         +  I++     R +K+  K K  Q     +
Sbjct: 7228 KSTKEVTEELFEEQPEEEISPEEEVPQKEVIEEIEEIVEEKRRLKKTKKPKLTQQVTEEE 7287

Query: 333  LPDVEKT-ELEQPLFSYEDIVESKKDENEIIQEKQTLE-ELPKEDVPEQYTITPRKSSAQ 390
             P  E   E E+ +   E+IVE KK   ++ + K   E +L +E++P + T+   +++  
Sbjct: 7288 TPHEEIIKESEEVVQEQEEIVEEKKKVKKVKKPKTVAEKQLKEEEIPTEETVEEEETAED 7347

Query: 391  KIDEIVDEVTIKKRLNPF-EIFYTPVEVRCGDTV 423
            +   + +   +KK   P   +  T VE   G+ V
Sbjct: 7348 QQLVVEESKKVKKVKKPTGTVEKTDVEELPGEEV 7381



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 75/392 (19%), Positives = 156/392 (39%), Gaps = 33/392 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
            P    KL+  +   ++  +LE ++       +     +I+     KY+      + KL I
Sbjct: 8090 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 8149

Query: 1077 RNTSVHDEGEYSCILRDES--CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT- 1131
               +  D G Y+C  ++E+   T+   ++  +    +      +K  +  K T   ++T 
Sbjct: 8150 AKVTPSDVGVYTCEAKNEAGVATSRTNIILGKFTKPLKIEFIEEKQPERLKVTVTCQVTG 8209

Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGNSKCTA-- 1187
            K +  V+W++   E+  S  +Q+  D K     L++ +   ++A  YS +  N    A  
Sbjct: 8210 KPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIG 8269

Query: 1188 ---ILTVEEPSINFTLRLP-----EFILVPANTDAYLTVEIPD-ETLDVTWYKK-KSVIE 1237
               IL+  +      L+ P       ++VP     +   +       +V W +  + +IE
Sbjct: 8270 NANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIE 8329

Query: 1238 DTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLDAKSTTKLKV------EVVEF 1286
            + E  T+I   +  T I      RK T   +      + +AKS+  + V      E ++ 
Sbjct: 8330 NEE--TIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKP 8387

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            P  I   E +Y  +    +   +  ++ P  + +W V+++ IK     +    +  ++L 
Sbjct: 8388 PRFIQPLEPKYFGEHEVAIIEAI-VESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLL 8446

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
            I+  ++   G +  R EN  G       V ++
Sbjct: 8447 IENFQSKFVGPFTCRAENVGGSVTSTATVNLI 8478



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)

Query: 529  FECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            FE ++E  G    ++ W +    ++ S     Y++   VA L I+++   DAGT+TC A 
Sbjct: 2558 FEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYVA-LTIKQLTIYDAGTYTCRAY 2616

Query: 587  NAAGFASSTTELIV 600
            NA G  ++  +L V
Sbjct: 2617 NAMGQDTTVAQLTV 2630



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 41/185 (22%), Positives = 77/185 (41%), Gaps = 15/185 (8%)

Query: 1102 VVELPPEIITRLQN-QKVNKGNKATFEIEL---TKGDALVRWFKDGSEIQFSNHIQLTID 1157
            VV + P  +T  ++     +G  A FE ++   T  +  V WFK+G  I   +  +   D
Sbjct: 3055 VVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHD 3114

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
                 L I     +D+G Y+C   N     ++  +E  +    R  E I+     +A L 
Sbjct: 3115 FGYVALDIVHLIAEDSGVYTCRAVN-----LIGSDETQVELQCRSGEQIVTVTQNEAGL- 3168

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             E      D + Y ++  I+++ K   +     + + I+   E+ +  + C L+   S  
Sbjct: 3169 -EQIHYLEDRSRYTRREEIDESTKQAPVFTTSLKNVEIK---ENQRAHFECRLIPV-SDP 3223

Query: 1278 KLKVE 1282
             ++VE
Sbjct: 3224 SMRVE 3228



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 1107 PEIITRLQN-QKVNKGNKATFEIELT-KGDALVR--WFKDGSEIQFSNHIQLTIDGKKQK 1162
            P   T LQ+  K+++G     E ++  + D  +R  WFK+G  +   + I+ T D     
Sbjct: 4258 PVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDFGLVT 4317

Query: 1163 LKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193
            L I     DD+  Y+C    +VG +  T+ L +E+
Sbjct: 4318 LSINGLRADDSAIYTCKATNQVGEAVSTSSLKIED 4352



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 16/62 (25%), Positives = 28/62 (45%)

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            EW  N K+++     +      + +L +   +  D G Y  R  N  G A++  N+  +D
Sbjct: 4700 EWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVD 4759

Query: 1380 KP 1381
            KP
Sbjct: 4760 KP 4761


>UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gambiae
            str. PEST|Rep: ENSANGP00000010739 - Anopheles gambiae
            str. PEST
          Length = 1776

 Score =  793 bits (1961), Expect = 0.0
 Identities = 439/1161 (37%), Positives = 630/1161 (54%), Gaps = 28/1161 (2%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A+  EGI  T A +TV+E    N + PLF+ RF+E +V + GTIKL ARVT NPVP I W
Sbjct: 627  ADILEGIPPT-AFLTVDESNVGNPQAPLFLERFEEQSVPQGGTIKLPARVTGNPVPEILW 685

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             RNN  + PS+ + Q +DGENIEL+I N DSE DSG+YKC+ASN+ GK+SHGARVT++V+
Sbjct: 686  LRNNNTLLPSKRVKQAYDGENIELLINNADSEQDSGNYKCIASNTIGKASHGARVTVEVD 745

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            KVTF K L+K+   EE ++V LEC+TSHTVSTKW+HN KE+SGMDHR I+QEG+      
Sbjct: 746  KVTFTKKLKKTITVEESRSVTLECETSHTVSTKWFHNGKELSGMDHRMIVQEGKVHKLNI 805

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                  D GV +C VKDQ+T   L V E  PEF+RKL+D E KEK+ A+LEVEI SETAD
Sbjct: 806  KNPTINDTGVYRCTVKDQQTECSLTVIEAKPEFLRKLEDVETKEKEHAVLEVEITSETAD 865

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
            V W ++G  +     KY+F K+G  R L++RNTSVHDEGEY+C L D+ C+AEV+V+ELP
Sbjct: 866  VTWYKEGRKLVDTTGKYEFAKKGKSRVLFVRNTSVHDEGEYTCALADQECSAEVSVIELP 925

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            PEII+  ++  V +G  A FE+ELTKGDALVRW+++  E+ F+ H+QLTIDGK+Q LKI 
Sbjct: 926  PEIISAPRDVTVARGEDAIFELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQTLKIN 985

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
                 D GEY+C VG  +  A LTVE+P ++F  RLPE  L   + DA   VE+  E+ D
Sbjct: 986  KTVDADGGEYTCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVEL-SESAD 1044

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            V WY+    I  + K+ L+ D   R LI++   EDD+ EYTC + +AK+++KLKVE+++ 
Sbjct: 1045 VVWYRNSKAITASSKYELVVDKCIRKLIVKNSVEDDENEYTCTVSNAKTSSKLKVEIIKV 1104

Query: 1287 PPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
             P I  D  R + I++  DVT  V + A P+P  EW VN ++I        ++  ++ASL
Sbjct: 1105 APTIFEDGARTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASL 1164

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
            TIK+    DAG + L+L N CG A     + I  +P  P  P    I   SI + W  P 
Sbjct: 1165 TIKRAAEVDAGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATLITDDSITLFWKAPS 1224

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            + GNS I  Y++EYQE +  +W  V +IT+T T++  L  N+ Y FRA A+NEV    AS
Sbjct: 1225 DDGNSKITEYLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPAS 1284

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT- 1524
              + YYK++   + ++PTV + LK++     + + L+CI  GVP P V W+R+G+ LK  
Sbjct: 1285 PNSPYYKIMAPIQKEAPTVSEHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQD 1344

Query: 1525 -AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ- 1582
                T                   Y   A N  G       + +  KP        +++ 
Sbjct: 1345 HTIVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVREL 1404

Query: 1583 -KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                V  EW   +   G+   +    K  +  +N        +       I++L  S   
Sbjct: 1405 SPEAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQY 1464

Query: 1642 KYTIEASNTAGTSS--VEVTLKV---YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
             + + A N  G S      T+K+    + PS P GP+    ++  S T+ W+P   +GG 
Sbjct: 1465 HFRVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMTSSSFTLMWQPSESNGGS 1524

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            ++T+Y +E  E     W KVA      ET   I+ L  N  Y F++ A+N VG SE L++
Sbjct: 1525 KITEYVVEVKEAKKKVW-KVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQT 1583

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII--DYKVEIKQEGKKW 1813
               ++                      +  +T          P++  +++      G  W
Sbjct: 1584 VESIVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDW 1643

Query: 1814 KXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
                          +  +   T   FRI+A N +G S P  S+         T PS P  
Sbjct: 1644 TKIKTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSE---------TVPSPPTG 1694

Query: 1872 FVVSESTSRSVTL-KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
             +       ++ + +W  PES+GG+PI  Y I  +  K   W ++  V        I+++
Sbjct: 1695 PLEVRYLGPNINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDL 1754

Query: 1931 KEKDEIIFRISAENTVGVSLP 1951
            +E ++ + RI A N VG+S P
Sbjct: 1755 QESEDYLIRIMARNEVGLSDP 1775



 Score =  530 bits (1309), Expect = e-148
 Identities = 356/1098 (32%), Positives = 555/1098 (50%), Gaps = 77/1098 (7%)

Query: 993  DVGVIKCIVKDQETSTMLVVKETIP----EFIRKLQD-FEVKEKDVAILEVEINSETADV 1047
            D G  KCI  +         + T+      F +KL+    V+E     LE E  S T   
Sbjct: 719  DSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLKKTITVEESRSVTLECE-TSHTVST 777

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W  +G+ +    ++   ++ G + KL I+N +++D G Y C ++D+     +TV+E  P
Sbjct: 778  KWFHNGKELSGMDHRMIVQE-GKVHKLNIKNPTINDTGVYRCTVKDQQTECSLTVIEAKP 836

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIY 1166
            E + +L++ +  +   A  E+E+T   A V W+K+G + +  +   +    GK + L + 
Sbjct: 837  EFLRKLEDVETKEKEHAVLEVEITSETADVTWYKEGRKLVDTTGKYEFAKKGKSRVLFVR 896

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            +  + D GEY+C + + +C+A ++V E  P I   +  P  + V    DA   +E+    
Sbjct: 897  NTSVHDEGEYTCALADQECSAEVSVIELPPEI---ISAPRDVTVARGEDAIFELELTKGD 953

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-- 1282
              V WY+ +  +       L  D K++TL I K  + D  EYTCV+ + ++  +L VE  
Sbjct: 954  ALVRWYRNEEELSFNGHVQLTIDGKRQTLKINKTVDADGGEYTCVVGEQRAKARLTVEKP 1013

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            VV+F  ++ +        R +D    V+       +  W  NSK I      +  +D   
Sbjct: 1014 VVDFVRRLPEVTLT---TRDNDAVFAVELSE--SADVVWYRNSKAITASSKYELVVDKCI 1068

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L +K     D   Y   + N       ++ V I+        P I E  + +  I  D
Sbjct: 1069 RKLIVKNSVEDDENEYTCTVSN--AKTSSKLKVEIIKVA-----PTIFEDGARTFTIRKD 1121

Query: 1403 EPENTG---NST----IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
            E        N+T      + V +   I + +++S         +I+      +  F    
Sbjct: 1122 EDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASLTIKRAAEVDAGEFTLKL 1181

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP---- 1511
             NE   + AS T     +IK+   Q    E P   + T    D  +T +F   P      
Sbjct: 1182 TNECGDASASFTL----IIKK---QPGAPEAPEATLIT----DDSIT-LFWKAPSDDGNS 1229

Query: 1512 KVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---- 1563
            K+T Y    ++  + K  + T                   ++  A N+ G+   S     
Sbjct: 1230 KITEYLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPASPNSPY 1289

Query: 1564 --VVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
              ++   QK   T+S E +K  H  +G    ++ ++ G+P P+V W++NG  L+ D  + 
Sbjct: 1290 YKIMAPIQKEAPTVS-EHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQD--HT 1346

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            I T  ++S I I  L R+H+ KYT+EA N AG+++VE+TLKV DKPSKPEGP+++RE+S 
Sbjct: 1347 IVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVRELSP 1406

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMF 1739
            E+V IEWKPP DDGGLE++++ IEK +  N N WIKVADV R++++YCIQKL ++ +Y F
Sbjct: 1407 EAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQYHF 1466

Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            RVIAQNPVG SE LES  + I+  ++ PS          + + S  + W PSE NGGS I
Sbjct: 1467 RVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMTSSSFTLMWQPSESNGGSKI 1526

Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
             +Y VE+K+  KK WK             I+ L++N  Y F+I A+N++G+S P  + + 
Sbjct: 1527 TEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQTVES 1586

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF-KTVKGKSWTKI 1915
            I  GK ++   + +   V    + +  +  +   +    P+     +  +T  G  WTKI
Sbjct: 1587 IVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDWTKI 1646

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
             T+  +   +C++N+KEK E++FRI AEN VG+S PT S+        TVPSPPT PLE+
Sbjct: 1647 KTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSE--------TVPSPPTGPLEV 1698

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
            R +G NI +  WG PE DGGAP+ GY IAIR+  KTMWMEVG+V  +   FNI+DL E+ 
Sbjct: 1699 RYLGPNINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDLQESE 1758

Query: 2036 TYMIRIYARNEIGLSEPL 2053
             Y+IRI ARNE+GLS+PL
Sbjct: 1759 DYLIRIMARNEVGLSDPL 1776



 Score =  432 bits (1065), Expect = e-119
 Identities = 430/1693 (25%), Positives = 735/1693 (43%), Gaps = 137/1693 (8%)

Query: 147  DLERVTLEKSDLFDSQEDESKPDVSQP---PQNII-EEAKSEPKLIEESEQPIAKTSEID 202
            ++E+  LE+ +  +  E + KP+  +P   PQ I  +E K++  LI E E+         
Sbjct: 135  EIEKTQLEQYEKVEL-ESKPKPEKLKPVLVPQKIERKEQKAQKMLISEPEEQPQMVRLRK 193

Query: 203  NEVPEKINVPD---DKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXX 259
             +VPE+  + +    K   +         K    +++ K+  V  P+   T D P +   
Sbjct: 194  VKVPERKEIEEVVVPKVLLKMKPKKKVEEKPKEEELDSKKRSVEKPKFTPT-DIPDYETP 252

Query: 260  XXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKE 319
                       E   V+ P+     +   +   P E    ++  +G  K+        ++
Sbjct: 253  LEPYVKPEPEPEEKPVQEPEKPKVPKEPKVPEVPEEPEHKIV--LGKGKKP---EPEPED 307

Query: 320  AAKVKKQVFVPPKLPDVEKTELE-QPLFSYEDIVESKKDENE----IIQEKQTLEELPKE 374
              K +K V   P  P+ EK E++ +P        E K+ E +    +   K   ++L + 
Sbjct: 308  EFKFRKPV---PTKPEEEKEEIKLKPFTKPTPDTEPKEREADRDMALPVPKDITKKLLEM 364

Query: 375  DVPEQYTITPRKSSAQKID---EIVDEVTIKKRLNPFE-IFYTPVEVRCGDTVFAVYSYV 430
            DVP+       K     +    E VDEVT+ KR    +       EV    ++      +
Sbjct: 365  DVPKTELEKYEKIDLDVVKPPKETVDEVTMVKRKPKVKPSVEEEEEVETKLSLPKKKPSI 424

Query: 431  AETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGW-VPAQYLMDENNYTQ------- 482
             E +EA    +  R   +    +D   V+  LT  K   VPA+  + E+   +       
Sbjct: 425  TEPEEAEATFKVARKPSVPQQAED---VEASLTITKEEEVPAEEEITEHVVVRKQRPRPK 481

Query: 483  --YLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540
              + ++ L+E+  ++   +K       +AP  +EKL+P  T DG TVQFEC+VEG+PRP 
Sbjct: 482  PAFRREVLDEEEVRIKKIKKVRQPRPPLAPKIIEKLQPITTQDGYTVQFECKVEGFPRPS 541

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            ITWFRQTA+IKPSQDFQ+YYDDDNVATL+IREVFPEDAGTFTCVAKN AGFASS TEL+V
Sbjct: 542  ITWFRQTAVIKPSQDFQIYYDDDNVATLIIREVFPEDAGTFTCVAKNIAGFASSATELVV 601

Query: 601  EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT-----------------FSKKPKAQ 643
            ++  SDHGS++              ADILEGIPPT                 F ++ + Q
Sbjct: 602  DSYSSDHGSDVATLSRKSMSRESSLADILEGIPPTAFLTVDESNVGNPQAPLFLERFEEQ 661

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             V +G  I L  R+   P P+I WL     ++P + +  A + +       L I N    
Sbjct: 662  SVPQGGTIKLPARVTGNPVPEILWLRNNNTLLPSKRVKQAYDGEN----IELLINNADSE 717

Query: 704  QE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
            Q+ G Y  +A N  G+AS    + ++  +    + ++  K++ V +  SV L  +   + 
Sbjct: 718  QDSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLK--KTITVEESRSVTLECET--SH 773

Query: 763  RPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
              +  W  N K +  +  +    +G  H + I  P  + D GVY    ++ +    T   
Sbjct: 774  TVSTKWFHNGKELSGMDHRMIVQEGKVHKLNIKNPT-INDTGVYRCTVKDQQ----TECS 828

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSET 878
            +TV E   E      F+ + +++  KEK    L   +T +    +TWY+   +++  +  
Sbjct: 829  LTVIEAKPE------FLRKLEDVETKEKEHAVLEVEIT-SETADVTWYKEGRKLVDTTGK 881

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                  G++  L + N  S  D G+Y C  ++        A V++ +E    +    +  
Sbjct: 882  YEFAKKGKSRVLFVRNT-SVHDEGEYTCALADQ----ECSAEVSV-IELPPEIISAPRDV 935

Query: 939  ETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
                G+  I E + T      +WY N++E+S   H ++  +G+            D G  
Sbjct: 936  TVARGEDAIFELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQTLKINKTVDADGGEY 995

Query: 998  KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV-AILEVEINSETADVVWERDGEII 1056
             C+V +Q     L V++ + +F+R+L +  +  +D  A+  VE+ SE+ADVVW R+ + I
Sbjct: 996  TCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVEL-SESADVVWYRNSKAI 1054

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITR-L 1113
                +KY+      IRKL ++N+   DE EY+C + +   +++  V ++++ P I     
Sbjct: 1055 TAS-SKYELVVDKCIRKLIVKNSVEDDENEYTCTVSNAKTSSKLKVEIIKVAPTIFEDGA 1113

Query: 1114 QNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            +   + K    TF ++          W  +   I  S     T+  +   L I      D
Sbjct: 1114 RTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASLTIKRAAEVD 1173

Query: 1173 AGEYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANT-DAYLTVEIPDETLDVTW 1229
            AGE++ ++ N     +A  T+           PE  L+  ++   +      D    +T 
Sbjct: 1174 AGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATLITDDSITLFWKAPSDDGNSKITE 1233

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD------AKSTT---KLK 1280
            Y  +   ++ +K+T ++ + + T  + K T++ +  +    ++      A   +   K+ 
Sbjct: 1234 YLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPASPNSPYYKIM 1293

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
              + +  P + ++ ++  +  G  VTL       P P+  W  N + +K+  HT  ++  
Sbjct: 1294 APIQKEAPTVSEHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQ-DHTIVTV-G 1351

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINI 1399
            +S+++ I  ++    G Y +   N  G A VE+ + ++DKPS P  P ++ E+   ++ I
Sbjct: 1352 QSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVRELSPEAVVI 1411

Query: 1400 CWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAV 1456
             W  P + G   I  + +E   + +   WI V ++ +   S  IQ L  ++ Y FR  A 
Sbjct: 1412 EWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQYHFRVIAQ 1471

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ---PKV 1513
            N V  S+  E+    K+ +  +  SP    P   I T        T ++         K+
Sbjct: 1472 NPVGCSEPLESAT-VKIQQTVEPPSP----PRGPIETSGMTSSSFTLMWQPSESNGGSKI 1526

Query: 1514 TWY----RDGKK--LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE-TSCVVG 1566
            T Y    ++ KK   K A  T  +                +K  A N  G  E    V  
Sbjct: 1527 TEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQTVES 1586

Query: 1567 IQQKPVITISNED----IKQKHKVGDEWLVTAVIEGIPPP--EVIWYKNGNKLENDKEYN 1620
            I     I+   ED    +        +  V+  +   P P  ++ W +      +D    
Sbjct: 1587 IVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDWTKI 1646

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
             T +       +  +K      + I A N  G SS  V+  V   PS P GP+ +R +  
Sbjct: 1647 KTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSETV---PSPPTGPLEVRYLGP 1703

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
                +EW  P  DGG  +  Y I         W++V  V  D +++ I+ L E+ +Y+ R
Sbjct: 1704 NINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDLQESEDYLIR 1763

Query: 1741 VIAQNPVGFSEAL 1753
            ++A+N VG S+ L
Sbjct: 1764 IMARNEVGLSDPL 1776



 Score =  231 bits (565), Expect = 2e-58
 Identities = 225/978 (23%), Positives = 405/978 (41%), Gaps = 71/978 (7%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  + R + Q V +G        +T      + W ++ + +  S  ++   DG+  +L I
Sbjct: 652  PLFLERFEEQSVPQGGTIKLPARVTGNPVPEILWLRNNNTLLPSKRVKQAYDGENIELLI 711

Query: 1166 YDCDLD-DAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
             + D + D+G Y C     +G +   A +TVE   + FT +L + I V  +    L  E 
Sbjct: 712  NNADSEQDSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLKKTITVEESRSVTLECET 771

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
               T+   W+     +   +   ++ + K   L I+  T +D   Y C + D +  T+  
Sbjct: 772  -SHTVSTKWFHNGKELSGMDHRMIVQEGKVHKLNIKNPTINDTGVYRCTVKDQQ--TECS 828

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            + V+E  P+ +    +   K      L V+  +       +    K++      + +   
Sbjct: 829  LTVIEAKPEFLRKLEDVETKEKEHAVLEVEITSETADVTWYKEGRKLVDTTGKYEFAKKG 888

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
            KS  L ++     D G Y   L +       E++V  L  P     P  + +      I 
Sbjct: 889  KSRVLFVRNTSVHDEGEYTCALADQ--ECSAEVSVIELP-PEIISAPRDVTVARGEDAIF 945

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
              E E T    ++ +    +E+     + +    K QT    LK N +          VD
Sbjct: 946  --ELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQT----LKINKT----------VD 989

Query: 1461 ISDASETTEYYKVIKETKIQSP-TVEKPLKNIT------TEPNEDIELTCIFGGVPQPKV 1513
                ++  EY  V+ E + ++  TVEKP+ +        T    D +            V
Sbjct: 990  ----ADGGEYTCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVELSESADV 1045

Query: 1514 TWYRDGKKLKTAKATYENRXXX-----XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             WYR+ K + TA + YE                      Y C   N     +TS  + ++
Sbjct: 1046 VWYRNSKAI-TASSKYELVVDKCIRKLIVKNSVEDDENEYTCTVSN----AKTSSKLKVE 1100

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
               V     ED  +   +  +  VT  ++    P PE  W  N   +    ++  T  E+
Sbjct: 1101 IIKVAPTIFEDGARTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEE 1160

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            T+ + IK      + ++T++ +N  G +S   TL +  +P  PE P     I+ +S+T+ 
Sbjct: 1161 TASLTIKRAAEVDAGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATL-ITDDSITLF 1219

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            WK P DDG  ++T+Y +E  E +  +W +V  +     T  + KL +N EY FR  A N 
Sbjct: 1220 WKAPSDDGNSKITEYLLEYQEKNQKKWTEVTSITETTTT--VTKLTKNAEYTFRATAINE 1277

Query: 1747 VGFSEALESEP---IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            VG   A  + P   I+     + P+             ++V ++   +    G P+ D  
Sbjct: 1278 VGKGPASPNSPYYKIMAPIQKEAPTVSEHLKDVHVGLGQTVTLSCIVT----GVPVPDVA 1333

Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTY--QFRIYARNEIGTSLPYTSDDKITIGK 1861
                 +  K           + I   S++  +  ++ + ARN  G++       ++T+ K
Sbjct: 1334 WFRNGQPLKQDHTIVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATV-----ELTL-K 1387

Query: 1862 TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVTVG 1919
             +  PS+P    VV E +  +V ++W  P  +GG  I+ + IE      K+ W K+  V 
Sbjct: 1388 VIDKPSKPEGPIVVRELSPEAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQ 1447

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
             ++  +CI+ + +  +  FR+ A+N VG S P ES +V++++    PSPP  P+E   + 
Sbjct: 1448 RNIKSYCIQKLIDSTQYHFRVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMT 1507

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
            S+     W   E +GG+ +  Y + +++  K +W   G    +     I +L+ N  Y  
Sbjct: 1508 SSSFTLMWQPSESNGGSKITEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDF 1567

Query: 2040 RIYARNEIGLSEPLESDE 2057
            +I A+N++G SEPL++ E
Sbjct: 1568 KITAKNKVGSSEPLQTVE 1585



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 4/94 (4%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P  P AP E  ++  + +   W  P  DG + +  Y +  ++  +  W EV  +   T  
Sbjct: 1200 PGAPEAP-EATLITDDSITLFWKAPSDDGNSKITEYLLEYQEKNQKKWTEVTSITETTT- 1257

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
              +  L++N  Y  R  A NE+G   P   + P+
Sbjct: 1258 -TVTKLTKNAEYTFRATAINEVG-KGPASPNSPY 1289



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 57/262 (21%), Positives = 104/262 (39%), Gaps = 10/262 (3%)

Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPE- 207
           E V  E++ + D ++ +   +    P+ + ++ K +PK  + SE+       ++ E+ + 
Sbjct: 80  ETVASEETTVLDDKKLKPTTEAQAEPKKVEKKVKKKPKKDKPSEEDEQLQRLLNLEIEKT 139

Query: 208 KINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXX 267
           ++   +  E    P     +  L P KIERKE +      +E  + PQ            
Sbjct: 140 QLEQYEKVELESKPKPEKLKPVLVPQKIERKEQKAQKMLISEPEEQPQMVRLRKVKVPER 199

Query: 268 XXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQV 327
              E   V +PK  LK + K      P+  + L S   S+++      +I +  +   + 
Sbjct: 200 KEIEE--VVVPKVLLKMKPKKKVEEKPKE-EELDSKKRSVEKPKFTPTDIPD-YETPLEP 255

Query: 328 FVPPKLPDVEK--TELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPR 385
           +V P+    EK   E E+P    E  V    +E E    K  L +  K +   +     R
Sbjct: 256 YVKPEPEPEEKPVQEPEKPKVPKEPKVPEVPEEPE---HKIVLGKGKKPEPEPEDEFKFR 312

Query: 386 KSSAQKIDEIVDEVTIKKRLNP 407
           K    K +E  +E+ +K    P
Sbjct: 313 KPVPTKPEEEKEEIKLKPFTKP 334


>UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isoform
            N2-A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to titin isoform N2-A - Strongylocentrotus
            purpuratus
          Length = 10984

 Score =  388 bits (956), Expect = e-106
 Identities = 352/1352 (26%), Positives = 584/1352 (43%), Gaps = 95/1352 (7%)

Query: 766  ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            I W K+ +   P +    K DG   S++I +    +D G YT+K      I + +    +
Sbjct: 1025 IVWMKDGQKITPDEKFQVKRDGRRLSLSI-QDTSPEDSGQYTIK------IGDKTQTADL 1077

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            +    E  +P   +N        E  TI L   ++   VP   WY+++ +I+    +   
Sbjct: 1078 KVQAAEFVKP---LNNTSAAEYDE--TIVLECELSNELVPC-QWYKDDVLITVGPKVEVI 1131

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             DG+  +LV+ +V  E D+G+++CV  +    +      T+DV+    +K L +    E 
Sbjct: 1132 DDGKKRKLVLHDVRPE-DTGNFRCVVGDKESSA------TLDVKASEIMKPLAEVTAPEF 1184

Query: 943  GKTVILECQTSHT-VSTKWYHNKKEISGMD----HREIIQEGRXXXXXXXXXXXXDVGVI 997
             +T +LEC+ SH      W  + + I+  +      E++ +GR            D    
Sbjct: 1185 AETAVLECEVSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEF 1244

Query: 998  KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
             C V D +T   + VK  +P   + L+D     +   +LE E+++E A V W ++G+ I 
Sbjct: 1245 TCKVGDNQTVANVNVK--VPSITKPLEDTTTAFETTVVLECEVDNEKAPVKWMKNGKEIT 1302

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
             K  KY  E +G  R+L I  T   DEG+Y+C++ DES  A + V   P E ++ +Q+ +
Sbjct: 1303 -KMPKYLMESKGKKRRLTIFETIPEDEGDYTCVVGDESTVAVLAVEPAPIEFLSEIQSVQ 1361

Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEY 1176
              +   A F  E++  +A V W K+  EI+  +   +  + GKK+ LKI   D+ D  E+
Sbjct: 1362 AVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEF 1421

Query: 1177 SCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW-YKKK 1233
            +C+  +   +A LTV E  P+I+ TL+  +  +   + +     E   ET DV W +K K
Sbjct: 1422 TCKTKDKTSSASLTVTEHIPTISHTLK--DVKIEEGSNEVVFECETDVETADVAWLHKGK 1479

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY 1293
             ++ED  KF +    ++ +LI++  + +D  E+TC +   ++  +L VEV EF   +   
Sbjct: 1480 DIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAELIVEV-EF---LAPL 1535

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
             +E     G ++T  V+     + +  W+ + + IK   + K   D K   L IKKV+  
Sbjct: 1536 PKEQSAIPGDEITFEVELTKDTE-DVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKVDFD 1594

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STI 1412
            D  +Y      N G    + N+ +   P     P +  I   +      E   TG+ + +
Sbjct: 1595 DDAVYSF----NAGDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAIEATVTGSPAAV 1650

Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
              +      I++T+   ++     + SI+ L  + + R           +D    T    
Sbjct: 1651 TTWSKGDTPIESTKRFKIEAGKGPKASIR-LTIDKTERSDLGTYTLTAANDLGTDTAIIF 1709

Query: 1473 VIKETKIQSPT----VEKPLKNIT---TEPNEDIELTCIFGGVPQPK-VTWYRDGKKLKT 1524
            +I   K Q PT     E   +++T   T P +D       GG P  + V   RD K+   
Sbjct: 1710 IIVLDKPQPPTSLSITETTPESVTLVWTAPEDD-------GGSPVIEYVIEKRDMKRNTW 1762

Query: 1525 AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-- 1582
             K    +                ++  A N+ G  E         +PV      D+    
Sbjct: 1763 TKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTT----SEPVTAKYQFDVPHAP 1818

Query: 1583 -KHKVGDEWLVTAVIEGIPPP-----EVIWYKNGNKLENDKEYNITTKEKTSVI--RIKE 1634
             K +  D       +   PP      EV  Y    K  +   +   TKE  + +  R+K+
Sbjct: 1819 SKPETSDVIQTEMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKD 1878

Query: 1635 LKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWK 1688
            L    S ++ + A N AGTS     S     K  YD P  P  P     +++ ++T+ W 
Sbjct: 1879 LIEGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTC-ENVNKTTITVSWT 1937

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPV 1747
            PP DDGG  +T Y IE+ +    RW+K  + D+  E T+ +  L +  +Y FR+ A+N  
Sbjct: 1938 PPEDDGGSPVTGYVIERCDVSRGRWVK-CNRDKVTELTFTVSDLTDGGQYQFRISAENAA 1996

Query: 1748 GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
            G  + +  S     K   D P            +   + ITW P E +GGSP+  + VE 
Sbjct: 1997 GVGQPSPTSATFTAKLPFDAPGAPGKPQVTEY-NITKMTITWTPPESDGGSPVTGFVVER 2055

Query: 1807 KQE-GKKWKXXX--XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
            K++   +W              +  L+  + YQFR+ A N  G        D        
Sbjct: 2056 KEKTSSRWVRVTKETVTETTLTVTGLTEGSEYQFRVIAENLAGPGPASEPSDLQKAKLPF 2115

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
              P+ P    ++ +    + L WT PES+GGSPIT Y IE K   GK WTK +    +  
Sbjct: 2116 DVPTAPGKPDITSADKTEMELTWTIPESDGGSPITGYTIEKKEKTGK-WTKAIKTVVTET 2174

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNI 1982
               +  + EK E  FR++A N  G    +E    ++ K    VP PP+ P    +  + I
Sbjct: 2175 TTTVTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVPGPPSKPTTENINKTTI 2234

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
             +T W  PE DGG+P+ GY +   +  +  W++  K  V  L   I DL E + Y  R+ 
Sbjct: 2235 TIT-WTPPENDGGSPVTGYIVEKCEGARGRWVKCNKDLVTELTLTISDLHEGNDYQFRVS 2293

Query: 2043 ARNEIGLSEPLESDEPFKV-IPGEGSHADEEP 2073
            A N  G+ +P    +  K  +P +   A  +P
Sbjct: 2294 AENAAGVGQPGPPSDTVKAKLPFDAPGAPGKP 2325



 Score =  338 bits (830), Expect = 1e-90
 Identities = 369/1483 (24%), Positives = 595/1483 (40%), Gaps = 126/1483 (8%)

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
            +LEC  V+ P+ +  WL  G+ I P+E  S   E         L I +V K     +T  
Sbjct: 1189 VLECE-VSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEFTCK 1247

Query: 712  AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
              + +  A++ +         + P + +PL+        +V+L  + V N +  + W KN
Sbjct: 1248 VGDNQTVANVNV---------KVPSITKPLEDTTTAFETTVVLECE-VDNEKAPVKWMKN 1297

Query: 772  NKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
             K +  +P    +S G    +TI +    +DEG YT       G   T AV+ VE     
Sbjct: 1298 GKEITKMPKYLMESKGKKRRLTIFETIP-EDEGDYTCVV----GDESTVAVLAVE----- 1347

Query: 829  NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGEN 887
               P  F++  Q +   E         ++ +    + W +N E I P  E       G+ 
Sbjct: 1348 -PAPIEFLSEIQSVQAVEDEPAVFTCEISDDNA-EVIWLKNEEEIKPDDEKYEFVVSGKK 1405

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT-V 946
              L I + D   D+ ++ C   +    +S    +T+  E +  + H  K  + EEG   V
Sbjct: 1406 RGLKIKSTDVS-DTAEFTCKTKDKTSSAS----LTV-TEHIPTISHTLKDVKIEEGSNEV 1459

Query: 947  ILECQTS-HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
            + EC+T   T    W H  K+I   + + +I ++GR            D G   C +   
Sbjct: 1460 VFECETDVETADVAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVH 1519

Query: 1005 ETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
            ET   L+V+    EF+  L ++      D    EVE+  +T DV W +DG+ IKP  N  
Sbjct: 1520 ETIAELIVE---VEFLAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDN-V 1575

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT--RLQNQKVNKG 1121
               K G   KL I+     D+  YS    D+ C   +  V  PP+I    +L N  V  G
Sbjct: 1576 KIVKDGKKHKLIIKKVDFDDDAVYSFNAGDQKCDCNLN-VSAPPKINVDPKLTNISVKAG 1634

Query: 1122 NKATFEIELTKGDALV-RWFKDGSEIQFSNHIQLTI-DGKKQ--KLKIYDCDLDDAGEYS 1177
             K   E  +T   A V  W K  + I+ +   ++    G K   +L I   +  D G Y+
Sbjct: 1635 TKIAIEATVTGSPAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYT 1694

Query: 1178 CEVGNSKCT-----AILTVEEP----SINFTLRLPEFILV----PANTDAYLTVEIPDET 1224
                N   T      I+ +++P    S++ T   PE + +    P +      +E   E 
Sbjct: 1695 LTAANDLGTDTAIIFIIVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEK 1754

Query: 1225 LDV---TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
             D+   TW K  +  E T +   +  V+    + R    ++             T K + 
Sbjct: 1755 RDMKRNTWTKVDTTSELTCRVPKL--VEGNEYLFRVSATNELGTSEPFTTSEPVTAKYQF 1812

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            +V   P K    E    I+    +T    D+    +    +I+  K   K +  K + ++
Sbjct: 1813 DVPHAPSK---PETSDVIQTEMTLTWTPPDFNGGSEVTG-YIIERKEADKTRWVKITKET 1868

Query: 1341 KSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVT------ILDKPSPPGKPNILEI 1392
             +  LT +  +  +   Y+ R+   N  G +      T        D P PP +P    +
Sbjct: 1869 VT-ELTFRVKDLIEGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTCENV 1927

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYR 1450
            + ++I + W  PE+ G S +  YV+E  ++    W+      +T+   ++ +L     Y+
Sbjct: 1928 NKTTITVSWTPPEDDGGSPVTGYVIERCDVSRGRWVKCNRDKVTELTFTVSDLTDGGQYQ 1987

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN-EDIELTCI----F 1505
            FR  A N   +   S T+  +      K+       P K   TE N   + +T       
Sbjct: 1988 FRISAENAAGVGQPSPTSATF----TAKLPFDAPGAPGKPQVTEYNITKMTITWTPPESD 2043

Query: 1506 GGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEV 1559
            GG P   VT +   +K KT+    + T E                 Y  + IA N  G  
Sbjct: 2044 GGSP---VTGFVVERKEKTSSRWVRVTKETVTETTLTVTGLTEGSEYQFRVIAENLAGPG 2100

Query: 1560 ETSCVVGIQQKPV-----ITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKNGNK 1612
              S    +Q+  +           DI    K   E  W +     G P       K    
Sbjct: 2101 PASEPSDLQKAKLPFDVPTAPGKPDITSADKTEMELTWTIPESDGGSPITGYTIEKKEKT 2160

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT------SSVEVTLKVYDKP 1666
             +  K       E T+   + +L      ++ + A N AGT      S  ++    YD P
Sbjct: 2161 GKWTKAIKTVVTETTTT--VTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVP 2218

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-T 1725
              P  P     I++ ++TI W PP +DGG  +T Y +EK E    RW+K  + D   E T
Sbjct: 2219 GPPSKPT-TENINKTTITITWTPPENDGGSPVTGYIVEKCEGARGRWVK-CNKDLVTELT 2276

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
              I  L+E  +Y FRV A+N  G  +    S+ +  K   D P            +   +
Sbjct: 2277 LTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKAKLPFDAPG-APGKPQVTEYNITKM 2335

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYA 1841
             ITW P E +GGSP+  + VE K+    +W              +  L+  + YQFR+ A
Sbjct: 2336 TITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIVTGLTEGSEYQFRVIA 2395

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             N  G        D          PS P    V+ +    + L W  P+S+GGSPIT YI
Sbjct: 2396 ENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSADKTQMELTWAVPDSDGGSPITGYI 2455

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            I+ K   GK WT+ +    +     I+++ EK E  FR++A N  G    +E    ++ K
Sbjct: 2456 IQKKENTGK-WTQSLKTTTTETTATIKSLIEKKEYEFRVAAVNLAGTGPFSEPSDYQIAK 2514

Query: 1962 HA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
                VP PP  P  + +  +++ +T W  PE DGG+P+ GY +  RD   + W +V +  
Sbjct: 2515 APYDVPGPPGKPTILEVDSTSMTIT-WTPPETDGGSPVTGYVVEKRDRVSSRWTKVKETS 2573

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            +  + + I DL E + Y  R+ A N+ G+ +P E  +  +  P
Sbjct: 2574 IEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKP 2616



 Score =  308 bits (755), Expect = 2e-81
 Identities = 220/802 (27%), Positives = 358/802 (44%), Gaps = 45/802 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++ G+   L V ++A P+P  +W  +   ++     K     +   +TIK     D G +
Sbjct: 7887 VRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSF 7946

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVV 1417
            KL + N  G   + + V +LD+P  P  P +  +I S+ + + W EP +TG S I +Y++
Sbjct: 7947 KLDVSNTAGSDAITIRVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYII 8006

Query: 1418 EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            E +E D T W  +      T   + +L+  +SY FR +AVN++  S+  ET E  K+ K+
Sbjct: 8007 ERREEDRTSWTRLTTRALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKK 8066

Query: 1477 TKI-QSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
              + ++P+  KPL    T  +  +E       GG P   ++ Y   KK +T+   +    
Sbjct: 8067 YDVPEAPS--KPLVTNVTSDSVTLEWHSPKSDGGAP---ISGYIIEKK-ETSSNYWSKVT 8120

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED--IKQKH------- 1584
                           +   +      E     G    P   I  ED  +  K        
Sbjct: 8121 TVSSGVTSHRIPRLMRGEEYEFRVSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEP 8180

Query: 1585 ---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
               KVG+ + +     GIP P V W  +G  L+      I T  + S I +K +++++  
Sbjct: 8181 IMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGG 8240

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
            +YTI   NTAG  S++V ++V+D+P  P GP+ M  +S  +VT+ W PP DDGG  +  Y
Sbjct: 8241 RYTINLKNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTY 8300

Query: 1702 AIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760
             ++K      +W K  + D  ++ TY +  L EN +Y FRV+A+N  G S+ LE + I  
Sbjct: 8301 VVQKRGEIETKW-KHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITP 8359

Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW--KXXX 1817
            +   +VP           I  +SV + W P   +GG+P+  Y VE++Q    +W      
Sbjct: 8360 QGQYNVPDPPSAPKVTNII-GDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLT 8418

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVS 1875
                   R  +L   T Y+FR+ A N  GT  P    + + +      P  +    F   
Sbjct: 8419 PTPDMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFEKV 8478

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEK 1933
             +     T +   P     +P  ++     TV+  +   I +   G ++     E     
Sbjct: 8479 ITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSG 8538

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
            D +   I A N  G    T + +V        PSPP  PL +  +GSN V  SW  P  D
Sbjct: 8539 DYV---IRASNKAGEDTVTVTVNV-----VDSPSPPQGPLALVKLGSNEVTLSWSRPRDD 8590

Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
            GG+P+ GY +  R+     W  V     +T  F +  L+E+  Y  R+ A N +G+SEPL
Sbjct: 8591 GGSPITGYVLEKREGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPL 8649

Query: 2054 ESDEPFKVIPGEGSHADEEPGE 2075
            ES+   ++IP       ++PG+
Sbjct: 8650 ESE---RIIPKGDYDVPDQPGK 8668



 Score =  284 bits (696), Expect = 2e-74
 Identities = 220/825 (26%), Positives = 365/825 (44%), Gaps = 55/825 (6%)

Query: 660  IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
            + + DI W+  G++I PDE   V  +         L I +      G YT+    + G+ 
Sbjct: 1020 VKDEDIVWMKDGQKITPDEKFQVKRDGRRLS----LSIQDTSPEDSGQYTI----KIGDK 1071

Query: 720  SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779
            +    LK++  E      ++PL +    + +  I+    + N      W K++  +   P
Sbjct: 1072 TQTADLKVQAAE-----FVKPLNNTSAAEYDETIVLECELSNELVPCQWYKDDVLITVGP 1126

Query: 780  TKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836
                  DG    + +L   + +D G +        G  E+SA + V+    E  +P    
Sbjct: 1127 KVEVIDDGKKRKL-VLHDVRPEDTGNFRCVV----GDKESSATLDVK--ASEIMKP---- 1175

Query: 837  NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGENIELVI 892
                E+T  E     ++     +P    TW ++ + I+P E  ++ +    DG    L+I
Sbjct: 1176 --LAEVTAPEFAETAVLECEVSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLII 1233

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
             +V  + D+ ++ C      G +   A V + V  +T  K L+ +    E  TV+LEC+ 
Sbjct: 1234 HDVVKD-DNAEFTC----KVGDNQTVANVNVKVPSIT--KPLEDTTTAFE-TTVVLECEV 1285

Query: 953  SHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV 1011
             +  +  KW  N KEI+ M    +  +G+            D G   C+V D+ T  +L 
Sbjct: 1286 DNEKAPVKWMKNGKEITKMPKYLMESKGKKRRLTIFETIPEDEGDYTCVVGDESTVAVLA 1345

Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
            V+    EF+ ++Q  +  E + A+   EI+ + A+V+W ++ E IKP   KY+F   G  
Sbjct: 1346 VEPAPIEFLSEIQSVQAVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKK 1405

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG-NKATFEIEL 1130
            R L I++T V D  E++C  +D++ +A +TV E  P I   L++ K+ +G N+  FE E 
Sbjct: 1406 RGLKIKSTDVSDTAEFTCKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECET 1465

Query: 1131 TKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189
                A V W   G +I + ++   +   G++  L + D  ++DAGE++C +G  +  A L
Sbjct: 1466 DVETADVAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAEL 1525

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
             VE   + F   LP+        +    VE+  +T DV W K    I+  +   ++ D K
Sbjct: 1526 IVE---VEFLAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGK 1582

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI-VDYE-REYRIKRGSDVTL 1307
            K  LII+K   DD   Y+    D K    L V     PPKI VD +     +K G+ + +
Sbjct: 1583 KHKLIIKKVDFDDDAVYSFNAGDQKCDCNLNVSA---PPKINVDPKLTNISVKAGTKIAI 1639

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI---DSKSASLTIKKVENTDAGIYKLRLEN 1364
                   P     W      I+  K  K         S  LTI K E +D G Y L   N
Sbjct: 1640 EATVTGSPAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAAN 1699

Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
            + G     + + +LDKP PP   +I E    S+ + W  PE+ G S +I YV+E +++  
Sbjct: 1700 DLGTDTAIIFIIVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEKRDMKR 1759

Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
              W  V   ++    +  L   + Y FR  A NE+  S+   T+E
Sbjct: 1760 NTWTKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTTSE 1804



 Score =  283 bits (693), Expect = 5e-74
 Identities = 281/1104 (25%), Positives = 452/1104 (40%), Gaps = 89/1104 (8%)

Query: 1003 DQETSTMLVVKETIP---EFIRKLQDFEVKEKDVAILEVEINSETAD--VVWERDGEIIK 1057
            D +T+  +   ET     + +  L D +V EK  A  E +++ +  D  +VW +DG+ I 
Sbjct: 976  DLQTTQQMADLETFSAEGQDLTPLADAKVPEKIAATFECDVSRDVKDEDIVWMKDGQKIT 1035

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
            P + K+  ++ G    L I++TS  D G+Y+  + D++ TA++ V     E +  L N  
Sbjct: 1036 PDE-KFQVKRDGRRLSLSIQDTSPEDSGQYTIKIGDKTQTADLKV--QAAEFVKPLNNTS 1092

Query: 1118 VNKGNKA-TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
              + ++    E EL+      +W+KD   I     +++  DGKK+KL ++D   +D G +
Sbjct: 1093 AAEYDETIVLECELSNELVPCQWYKDDVLITVGPKVEVIDDGKKRKLVLHDVRPEDTGNF 1152

Query: 1177 SCEVGNSKCTAILTVEEPSINFTL---RLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
             C VG+ + +A L V+   I   L     PEF    A T A L  E+     + TW K  
Sbjct: 1153 RCVVGDKESSATLDVKASEIMKPLAEVTAPEF----AET-AVLECEVSHPKAEATWLKDG 1207

Query: 1234 SVIEDTE----KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
              I   E    K+ ++SD +KR LII    +DD  E+TC + D ++   + V+V      
Sbjct: 1208 QPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEFTCKVGDNQTVANVNVKVPSITKP 1267

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
            + D    +     + V L  +      P  +W+ N K I K          K   LTI +
Sbjct: 1268 LEDTTTAFE----TTVVLECEVDNEKAP-VKWMKNGKEITKMPKYLMESKGKKRRLTIFE 1322

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
                D G Y       C   D      +  +P+P     + EI   S+    DEP     
Sbjct: 1323 TIPEDEGDY------TCVVGDESTVAVLAVEPAP--IEFLSEI--QSVQAVEDEP----- 1367

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                 +  E  + D  E I +KN  + +   +  +   S + R   +   D+SD +E T 
Sbjct: 1368 ---AVFTCEISD-DNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEFT- 1422

Query: 1470 YYKVIKETKIQS-------PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
              K   +T   S       PT+   LK++  E   +  +      V    V W   GK +
Sbjct: 1423 -CKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECETDVETADVAWLHKGKDI 1481

Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI-- 1580
                   E+                 K ++  D GE   +C +G+ +     I   +   
Sbjct: 1482 ------VEDNSKFVIKRKGRRHSLIVKDVSVEDAGEF--TCRIGVHETIAELIVEVEFLA 1533

Query: 1581 ---KQKHKV-GDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
               K++  + GDE  +T  +E     E V W K+G K++      I    K   + IK++
Sbjct: 1534 PLPKEQSAIPGDE--ITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKV 1591

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
                 + Y    S  AG    +  L V   P     P +     +    I  +  +    
Sbjct: 1592 DFDDDAVY----SFNAGDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAIEATVTGSP 1647

Query: 1696 LELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
              +T ++      ++ +  K+      +      I K   +    + + A N +G   A 
Sbjct: 1648 AAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAANDLGTDTA- 1706

Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK- 1812
                I+    LD P              ESV + W   E +GGSP+I+Y +E K++ K+ 
Sbjct: 1707 ----IIFIIVLDKPQPPTSLSITETTP-ESVTLVWTAPEDDGGSPVIEYVIE-KRDMKRN 1760

Query: 1813 -WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
             W           R+ KL     Y FR+ A NE+GTS P+T+ + +T       P  P  
Sbjct: 1761 TWTKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTTSEPVTAKYQFDVPHAPSK 1820

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
               S+     +TL WT P+ NGGS +T YIIE K      W KI     +     ++++ 
Sbjct: 1821 PETSDVIQTEMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKDLI 1880

Query: 1932 EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
            E     FR+ A N  G S P+E S   + +    VP PP  P     V    +  SW  P
Sbjct: 1881 EGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQP-TCENVNKTTITVSWTPP 1939

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            E DGG+P+ GY I   DV++  W++  +  V  L F + DL++   Y  RI A N  G+ 
Sbjct: 1940 EDDGGSPVTGYVIERCDVSRGRWVKCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVG 1999

Query: 2051 EPLESDEPFKV-IPGEGSHADEEP 2073
            +P  +   F   +P +   A  +P
Sbjct: 2000 QPSPTSATFTAKLPFDAPGAPGKP 2023



 Score =  277 bits (679), Expect = 2e-72
 Identities = 205/786 (26%), Positives = 342/786 (43%), Gaps = 31/786 (3%)

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
            ++     K G    + V Y   P P   W  + + +K   H +    ++++++T+K VE 
Sbjct: 8177 FDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEK 8236

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411
             + G Y + L+N  G   +++ V + D+P PP  P  +  +  S++ + W  P + G S 
Sbjct: 8237 ANGGRYTINLKNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSESTVTLSWSPPSDDGGSR 8296

Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            I  YVV+ +    T+W  V    I      +  LK N  Y+FR  A N+   S   E   
Sbjct: 8297 IFTYVVQKRGEIETKWKHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQS 8356

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
                 +      P+  K    I              GG P    V   R     +  KAT
Sbjct: 8357 ITPQGQYNVPDPPSAPKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKAT 8416

Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQK 1583
                               Y  +  A N  G     E S  V ++   V    N D + +
Sbjct: 8417 LTPTPDMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFE 8476

Query: 1584 H----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                 + G  + +    +  P P V W +NG+ ++      I +    + +  +  +R+ 
Sbjct: 8477 KVITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTD 8536

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
            S  Y I ASN AG  +V VT+ V D PS P+GP+ + ++    VT+ W  P DDGG  +T
Sbjct: 8537 SGDYVIRASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPIT 8596

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
             Y +EK E     W  V+    D  T+ + KL E+ EY FRV A+N +G SE LESE I+
Sbjct: 8597 GYVLEKREGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPLESERII 8655

Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXX 1816
             K   DVP           I ++SV +TW   +++GG+P+  Y VE ++ G+    W   
Sbjct: 8656 PKGDYDVPD-QPGKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRT 8714

Query: 1817 XX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFV 1873
                      R+ +LS    Y+FR+ A N+ G S P  +   + + + +  P     +  
Sbjct: 8715 SYKPVMDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQF 8774

Query: 1874 VSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIK 1931
                T R+ TL   + P S   +P   ++++ K V  G+      T   +V  +  ++ +
Sbjct: 8775 RDVITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTN--KDAR 8832

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
              D   + I   N  G    T   +V L+K    PS P  P+++  +  + V  +W  P+
Sbjct: 8833 RTDSGTYTIKISNKAGTDTATIRVAV-LDK----PSAPEGPIKVTSITCDSVTLAWEPPK 8887

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             DGGA + GY +  R+  +  W  V    +++ ++ +  L +  +Y+ R+ A ++ G SE
Sbjct: 8888 DDGGADITGYILERREPDQFRWTRVTST-LSSPRYAVTGLKDGRSYLFRVRAVSKYGESE 8946

Query: 2052 PLESDE 2057
            PLE+++
Sbjct: 8947 PLETED 8952



 Score =  254 bits (621), Expect = 3e-65
 Identities = 178/696 (25%), Positives = 301/696 (43%), Gaps = 27/696 (3%)

Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVK 1431
            ++L KP    P  P + +   +S+ + W+ PE+ G S I  YV+E +E  +  W   + +
Sbjct: 7668 SVLVKPPYGRPSPPVVTDFTKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQ 7727

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            +I K + ++++LK  + Y FR  A+N+  I   S+ +E      +  + SP  E  + NI
Sbjct: 7728 SILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDGSELATAKSKFGVPSPPGEPTISNI 7787

Query: 1492 TTEPNEDIELT--CIFGGVPQPKVTWYRDGKKLKTAKATYENR----XXXXXXXXXXXXX 1545
            T + +  +  T     GG P    T  R   +  T      +                  
Sbjct: 7788 TAK-SVTLNWTPPSSDGGSPVTGYTVER-ADRFSTRWVPVNSHPIKDTKMDIHDLPATGS 7845

Query: 1546 XXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
              ++ +A N  G  + +     +G+   P +           +VG  + +    +  P P
Sbjct: 7846 YQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDTYKYHDTMVVRVGATFNLDVPFKATPKP 7905

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             V W K+G+ L+      I T ++ +++ IK   R     + ++ SNTAG+ ++ + ++V
Sbjct: 7906 TVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSNTAGSDAITIRVQV 7965

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             D+P +P GP++ ++I    + + WK P D GG  +T Y IE+ E D   W ++     D
Sbjct: 7966 LDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTTRALD 8025

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDN 1781
              T  +  L E   Y+FRV A N +G SE LE+ E I +K   DVP           + +
Sbjct: 8026 T-TVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDVPE-APSKPLVTNVTS 8083

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WK--XXXXXXXXXARIQKLSINTTYQFR 1838
            +SV + W   + +GG+PI  Y +E K+     W             RI +L     Y+FR
Sbjct: 8084 DSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRIPRLMRGEEYEFR 8143

Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            + A N  G     T    I    T   P     F          + +   P +   +P  
Sbjct: 8144 VSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAV 8203

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             +  + + +K  +  +I T         ++N+++ +   + I+ +NT G     ES  V 
Sbjct: 8204 TWSFDGRPLKPSAHIRIDT-SNRASTITVKNVEKANGGRYTINLKNTAG----AESLDVE 8258

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
            +      P PP  PLE+  V  + V  SW  P  DGG+ +  Y +  R   +T W  V K
Sbjct: 8259 VRVFDR-PGPPRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKHVNK 8317

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
              +  L + +  L EN  Y  R+ A N+ G S+PLE
Sbjct: 8318 DYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLE 8353



 Score =  247 bits (604), Expect = 3e-63
 Identities = 194/705 (27%), Positives = 300/705 (42%), Gaps = 42/705 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            D P  PGKP + E + + + I W  PE+ G S +  +VVE +E  ++ W+ V   T T+T
Sbjct: 2317 DAPGAPGKPQVTEYNITKMTITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTET 2376

Query: 1439 S--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEP 1495
            +  +  L   S Y+FR  A N      ASE ++  K   +    +P+   KP   +T+  
Sbjct: 2377 TLIVTGLTEGSEYQFRVIAENPAGPGPASEPSDLQKA--KLPFDAPSAPGKP--EVTSAD 2432

Query: 1496 NEDIELTCIF----GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
               +ELT       GG P   +T Y   KK  T K T   +                K  
Sbjct: 2433 KTQMELTWAVPDSDGGSP---ITGYIIQKKENTGKWTQSLKTTTTETTATIKSLIEKKEY 2489

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV----TAVIEGIPPPEVIWY 1607
             F     V  +      +     I+          G   ++    T++     PPE    
Sbjct: 2490 EFRV-AAVNLAGTGPFSEPSDYQIAKAPYDVPGPPGKPTILEVDSTSMTITWTPPETDGG 2548

Query: 1608 K--NGNKLEN-DKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAGT------ 1653
                G  +E  D+  +  TK K + I      I +LK  +  ++ + A N AG       
Sbjct: 2549 SPVTGYVVEKRDRVSSRWTKVKETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEP 2608

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            S        YD P  P  P I  ++ +  +T+ W PP DDGG ++  Y +EK + D  RW
Sbjct: 2609 SDQRRAKPPYDVPGPPGIPDIS-DVDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRW 2667

Query: 1714 IKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXX 1771
             K    D   E T  +  L E   YMFRV A+N  G  E+ L ++P   K   D P    
Sbjct: 2668 TKAHKEDLVTELTLTVYDLTEGTNYMFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPP 2727

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX--XXARIQK 1828
                   +D  S+++TW P + +GGS +  Y +E + + + KW              +  
Sbjct: 2728 PPTPTH-VDRTSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEISFTVTG 2786

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
            L+ +  Y FR+ A N+ G   P    D +        P  P   V S+ T  SV L+W+ 
Sbjct: 2787 LTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETSVHLEWSP 2846

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            P +NGG+ IT YI+E K      WTK     G      ++++KE +E  FR+ A N  G 
Sbjct: 2847 PSNNGGAEITEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVIAVNPAGP 2906

Query: 1949 SLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
              P+++    + K    VP  P  P    +  +++ +T W  P  DGG+P+ GY + ++D
Sbjct: 2907 GSPSDACKPFVAKPPYDVPDAPGKPAPSDLSPTSVTLT-WTPPPSDGGSPITGYTVEMKD 2965

Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
               T W +  +  ++     + DL E   Y  R+ A N+ G S+P
Sbjct: 2966 KFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKP 3010



 Score =  244 bits (598), Expect = 2e-62
 Identities = 191/811 (23%), Positives = 346/811 (42%), Gaps = 45/811 (5%)

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            P I+   +  + I V A T  +L V I    T  V W   +  ++D  +    +      
Sbjct: 8766 PKIDLGSQFRDVITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAV 8825

Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            L  +     D   YT  + +     T  ++V V++ P       +   I   S VTL   
Sbjct: 8826 LTNKDARRTDSGTYTIKISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDS-VTL--- 8881

Query: 1311 YQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
              A+  P D+       +I+  +   + + T+ +    S    +  +++  + ++++R  
Sbjct: 8882 --AWEPPKDDGGADITGYILERREPDQFRWTRVTSTLSSPRYAVTGLKDGRSYLFRVRAV 8939

Query: 1364 NNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            +  G ++ +E    IL     +KP  PG P    +   SI + W  P + G + I  Y++
Sbjct: 8940 SKYGESEPLETEDAILIKSAFEKPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYIL 8999

Query: 1418 EYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            E +E   T W+    K +      +  L     Y FR  A NE  +   S+T+    ++ 
Sbjct: 9000 EIKETRGTRWLRATRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSA--PIVS 9057

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYEN 1531
            +T I+     +PLK+++ +  + + L C     P  +V W +DG ++    +  +     
Sbjct: 9058 KTPIELAEFVEPLKDVSAKAGKIVTLECRISN-PNAEVKWMKDGFQIFGYDRVNEIKEGQ 9116

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
            R               Y C    + G+  TSC + +   P I +         K G+   
Sbjct: 9117 RRAITLRNVGDRDTGKYSC----ECGKQSTSCWLSVTAPPTIDVKAYKDVVVVKTGNTLR 9172

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +     G P P+V W+++  ++  D   +I T++  + I I+ + R  + K++I  +N A
Sbjct: 9173 LLVPYTGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEA 9232

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G  +  + + V D P  P GP+ + ++ R  V++ W+PP DDGG  +  Y +E+ E +  
Sbjct: 9233 GQETAIIRVNVIDVPGPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRR 9292

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXX 1770
             W  V++    V  + +  L+E  EY FRV A+N  G    L   EP+VI     VP+  
Sbjct: 9293 MWTSVSNYVSHV-PFTVSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPT-P 9350

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK--XXXXXXXXXARIQ 1827
                    +  + + +TW     +GG PI  Y +E ++   K+W              I+
Sbjct: 9351 PGKPEISNVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIK 9410

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKW 1886
             L+  + Y+FRI A N+ G   P        + ++    P+ P   ++ + T+ SV+L W
Sbjct: 9411 GLTEGSNYEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATSVSLSW 9470

Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946
            + P ++GGS IT+YI+E +      W     V  +     + N+ E  E  FR++A N  
Sbjct: 9471 SAPSTDGGSEITHYIVERRLKGSYMWIDRTVVHDT--SCSVNNLVEDKEYTFRVTAVNAA 9528

Query: 1947 GVSLPTESQSVRLEKHATVP-SPPTAPLEIR 1976
            G        S      + +P + P+  +EI+
Sbjct: 9529 GNESDPSRASESFVAESQLPGAAPSILIEIQ 9559



 Score =  237 bits (581), Expect = 2e-60
 Identities = 199/818 (24%), Positives = 349/818 (42%), Gaps = 50/818 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVI 753
            L + +V+    G +  V  ++E  A+L +         +  ++++PL  +   +  E+ +
Sbjct: 1139 LVLHDVRPEDTGNFRCVVGDKESSATLDV---------KASEIMKPLAEVTAPEFAETAV 1189

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEG 812
            L  +V  +P+   TW K+ +P+    T  +  +    ++   + +   ++  +K +N+E 
Sbjct: 1190 LECEV-SHPKAEATWLKDGQPI----TPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEF 1244

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
              +     TV      N + P      ++ T   + T+ L   V     P + W +N + 
Sbjct: 1245 TCKVGDNQTV---ANVNVKVPSITKPLEDTTTAFETTVVLECEVDNEKAP-VKWMKNGKE 1300

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            I+          G+   L I     E D GDY CV     G  S  A + ++   + F+ 
Sbjct: 1301 ITKMPKYLMESKGKKRRLTIFETIPE-DEGDYTCVV----GDESTVAVLAVEPAPIEFLS 1355

Query: 933  HLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXX 990
             +Q S +  E +  +  C+ S       W  N++EI   D + E +  G+          
Sbjct: 1356 EIQ-SVQAVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTD 1414

Query: 991  XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVVW 1049
              D     C  KD+ +S  L V E IP     L+D +++E  +  + E E + ETADV W
Sbjct: 1415 VSDTAEFTCKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECETDVETADVAW 1474

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
               G+ I    +K+  +++G    L +++ SV D GE++C +      AE+ +VE+  E 
Sbjct: 1475 LHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAEL-IVEV--EF 1531

Query: 1110 ITRL-QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            +  L + Q    G++ TFE+ELTK    V W KDG +I+  +++++  DGKK KL I   
Sbjct: 1532 LAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKV 1591

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEP-SINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
            D DD   YS   G+ KC   L V  P  IN   +L   I V A T   +   +      V
Sbjct: 1592 DFDDDAVYSFNAGDQKCDCNLNVSAPPKINVDPKLTN-ISVKAGTKIAIEATVTGSPAAV 1650

Query: 1228 T-WYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            T W K  + IE T++F + +    +    L I K    D   YT    +   T    + +
Sbjct: 1651 TTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAANDLGTDTAIIFI 1710

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLL--VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            +                    VTL+          P  E+++  + +K+   TK    S+
Sbjct: 1711 IVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEKRDMKRNTWTKVDTTSE 1770

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTI---LDKPSPPGKPNILEIDSS 1395
                  K VE  +  ++++   N  G ++       VT     D P  P KP   ++  +
Sbjct: 1771 LTCRVPKLVEGNEY-LFRVSATNELGTSEPFTTSEPVTAKYQFDVPHAPSKPETSDVIQT 1829

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRA 1453
             + + W  P+  G S +  Y++E +E D T W+ +   T T+ +  +++L   +SY FR 
Sbjct: 1830 EMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKDLIEGTSYEFRV 1889

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            YA+N+   S  SE +   K      +  P  +   +N+
Sbjct: 1890 YAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTCENV 1927



 Score =  236 bits (578), Expect = 4e-60
 Identities = 169/605 (27%), Positives = 280/605 (46%), Gaps = 42/605 (6%)

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
            +E+   I+ G    + + Y+A P P   W  N   ++K        ++   +LT +  E 
Sbjct: 8475 FEKVITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAER 8534

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411
            TD+G Y +R  N  G   V + V ++D PSPP  P  ++++ S+ + + W  P + G S 
Sbjct: 8535 TDSGDYVIRASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSP 8594

Query: 1412 IIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            I  YV+E +E     W +V + I  T   +  L  +  Y+FR  A N + +   SE  E 
Sbjct: 8595 ITGYVLEKREGGYGSWTNVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGV---SEPLES 8651

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVPQPKVTWYRDGKKLKTAK 1526
             ++I +     P     +K + T  ++ + LT       GG P   VT Y   K+ +   
Sbjct: 8652 ERIIPKGDYDVPDQPGKIK-VDTIQSDSVSLTWSRPQRDGGAP---VTGYIVEKRERGQP 8707

Query: 1527 ATYENRXXXXXXXXXX--------XXXXXYKCIAFNDHG---EVETSCVVGIQQ---KPV 1572
                NR                       ++  A N  G      T+  V +++    P 
Sbjct: 8708 EAGWNRTSYKPVMDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPK 8767

Query: 1573 ITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            I + ++  D+    + G  + +   I G P P V W  +  ++++ +    +T   ++V+
Sbjct: 8768 IDLGSQFRDVITV-RAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVL 8826

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690
              K+ +R+ S  YTI+ SN AGT +  + + V DKPS PEGP+ +  I+ +SVT+ W+PP
Sbjct: 8827 TNKDARRTDSGTYTIKISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDSVTLAWEPP 8886

Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
             DDGG ++T Y +E+ EPD  RW +V         Y +  L +   Y+FRV A +  G S
Sbjct: 8887 KDDGGADITGYILERREPDQFRWTRVTST-LSSPRYAVTGLKDGRSYLFRVRAVSKYGES 8945

Query: 1751 EALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808
            E LE+E  I+IK+A + P           + ++S+ ++W P   +GG+ I +Y +EIK+ 
Sbjct: 8946 EPLETEDAILIKSAFEKPP-APGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKET 9004

Query: 1809 EGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIG------TSLPYTSDDKITIG 1860
             G +W             R+  LS    Y+FR+ A NE G      TS P  S   I + 
Sbjct: 9005 RGTRWLRATRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSAPIVSKTPIELA 9064

Query: 1861 KTLTP 1865
            + + P
Sbjct: 9065 EFVEP 9069



 Score =  235 bits (576), Expect = 7e-60
 Identities = 189/734 (25%), Positives = 297/734 (40%), Gaps = 33/734 (4%)

Query: 1358 YKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            +++  +N  G +      T   KP   P +P+I ++  +S+ + W  PE+ G S +  Y+
Sbjct: 5645 FRVVAKNKAGASQPSSVATFSIKPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYI 5704

Query: 1417 VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            VE +E D   W+      IT T  ++Q+L     Y FR  A N+  +  ASE ++     
Sbjct: 5705 VERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVIAK 5764

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDI-ELTCIFGGVPQPK-VTWYRDGKKLKTAKATYENR 1532
                +    V+  + NIT    E         GG P    V   +D   ++        +
Sbjct: 5765 PPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEMKDKFGVRWTSLGKPTK 5824

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIK---QKHKVGD 1588
                           ++  A N  GE E      IQ  KP++     D+    +K +   
Sbjct: 5825 TSFKVTNLKTGSEYEFQVRAENKAGEGEP-----IQSTKPIVAKDAYDVPDAPEKPEPSS 5879

Query: 1589 EWLVTAVIEGIPPP-----EVIWYKNGNKLENDKEYNITTKEKT--SVIRIKELKRSHSS 1641
                +  +   PP      ++  Y    K +    +   T++    + + + +L+     
Sbjct: 5880 LTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEY 5939

Query: 1642 KYTIEASNTAGTSSVEVTL------KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
             + + A N AG S            K Y  P  P  P     I+  S T+ WK P  DGG
Sbjct: 5940 TFRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASN-ITETSATLNWKAPTSDGG 5998

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754
              +T Y IEK E  + RW      D    ++ ++ L    EY FRV A N  G  + ++ 
Sbjct: 5999 SPITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAAVNKAGSGKPSVP 6058

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW 1813
            SE    +     P             N SV ++W P   +GGS IIDY VE K     +W
Sbjct: 6059 SETFKAQPPYAAPEAPSAPVIEEVTAN-SVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRW 6117

Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                        + KL      QFR+ A N+ G   P  S   +T+    T P  P    
Sbjct: 6118 TEVNRTPETTFTVPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPT 6177

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
              E  + S+T++W+ P+++GGS ITNYI+E K      W ++ T   S   + +  +KE 
Sbjct: 6178 AVEVDAVSITVRWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKEN 6237

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992
              + FR+ A N  G   P+        K   TVPS P AP ++  V +  +  +W     
Sbjct: 6238 QTLEFRVIAVNKAGEGKPSSVGGPFTTKATYTVPSAPGAP-DVSNVKATSMTVTWTKSIS 6296

Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            DGG+P+ GY +   DV+   W+ V +V +      +  L E   Y  R+ A N  G S+P
Sbjct: 6297 DGGSPITGYVLEKCDVSTGRWVPVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKP 6356

Query: 2053 LESDEPFKVIPGEG 2066
             E  + +   P  G
Sbjct: 6357 SEPSKAYIAKPPYG 6370



 Score =  235 bits (575), Expect = 1e-59
 Identities = 196/722 (27%), Positives = 301/722 (41%), Gaps = 37/722 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKT 1436
            D PS PG P+I +I S+++ + W  PE+ G + II ++VE +E  +T W+ +   + T+T
Sbjct: 6773 DLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISRFDFTET 6832

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
              S+  LK  + Y FR  A N++ I   SE T   K  KE   +SP+    + NIT E +
Sbjct: 6833 TFSVTGLKDGNDYEFRVAAKNKIGIGKFSEPTRPTKA-KE-PYESPST-PDVSNITGE-S 6888

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX-----XXXXXXXXYKCI 1551
              +  T        P   +  + ++   +  T  NR                    ++ I
Sbjct: 6889 MTLNWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAEYEFRVI 6948

Query: 1552 AFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP-----PEVI 1605
            A N  G    S V      KP  T     I  + +V D    T  I   PP      ++ 
Sbjct: 6949 AENKAGLGRPSQVTHPFTAKPPYT--TPGIPDQPEVEDVTATTITISWSPPSYDGGSKIT 7006

Query: 1606 WYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVT 1659
             Y   +K +    +  I +    +      LK     ++ + A N AG       S  VT
Sbjct: 7007 GYTIESKSDATMRWVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVT 7066

Query: 1660 LK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             K  YD P  P+ P +   I+  S  + W  P  DGG  +T Y I+K +  + RW+K  +
Sbjct: 7067 CKPPYDPPPPPDAPDVY-NITPTSAALTWSTPRQDGGSPITGYVIDKKDKYSTRWVKADE 7125

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXX 1777
            V      + I+ L    +Y FRV A N  G  + +   E    K    VP          
Sbjct: 7126 VPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPD-APSPPSVS 7184

Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXXXXARIQKLSINTT 1834
             I   S+ ++W P   +GGS +  Y VE ++    +W             ++  LS +  
Sbjct: 7185 DITPSSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLSEDRK 7244

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y+FR+ A N  G   P               PS P     +   S  + L+WT P ++GG
Sbjct: 7245 YEFRVSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATNVDSTELVLEWTAPVADGG 7304

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
            SPITNY+IE +   G  W+KI     +     +  +K  DE  FR+ AEN VG+  P+++
Sbjct: 7305 SPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAENKVGLGRPSDN 7364

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS--WGTPEWDGGAPLLGYNIAIRDVTKTM 2012
                + K       P AP  +++ G+     S  W  P  DGG+P+ GY +  +D     
Sbjct: 7365 TESIVAKPPY--DTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSAR 7422

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV-IPGEGSHADE 2071
            W  V +V V      + DL E   Y  R+ A N  G+    +S +P  +  P +   A  
Sbjct: 7423 WTRVNRVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPVDAPSAPL 7482

Query: 2072 EP 2073
            EP
Sbjct: 7483 EP 7484



 Score =  233 bits (570), Expect = 4e-59
 Identities = 186/700 (26%), Positives = 289/700 (41%), Gaps = 37/700 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            D P  P  P I ++ + S+ I W  P + G S +  Y++E +E  +++W+ V        
Sbjct: 5472 DVPESPDTPKISDVTNDSMVISWQPPYSDGGSKVTEYIIEKKEPYSSKWVPVTKTRDLSY 5531

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT------ 1492
             I  LK N  Y FR  AVN+   S+ S  T   K      + S      + +++      
Sbjct: 5532 KITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVPSQPHSLKIADVSPTSLTL 5591

Query: 1493 --TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550
              +EP+ D     + G + + K    R   +      T  +                ++ 
Sbjct: 5592 EWSEPDSD-GGDNVSGYIIEKK---DRFSPRWTPVNQTAISDTKFKVTGLKDGQDCEFRV 5647

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            +A N  G  + S V     KP    S  DIK+  ++ V   W       G P    I   
Sbjct: 5648 VAKNKAGASQPSSVATFSIKPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYI--- 5704

Query: 1609 NGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYD 1664
               + E D++Y +         +   +++L   H  ++ + A N AG     E +  V  
Sbjct: 5705 -VERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVIA 5763

Query: 1665 KP--SKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
            KP    P+ PV +    I++ S  + W PP+DDGG  +T Y +E  +    RW  +    
Sbjct: 5764 KPPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEMKDKFGVRWTSLGKPT 5823

Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXI 1779
            +   ++ +  L    EY F+V A+N  G  E ++S +PIV K A DVP           +
Sbjct: 5824 K--TSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPD-APEKPEPSSL 5880

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKW--KXXXXXXXXXARIQKLSINTTYQ 1836
               SV +TW P   +GGS I  Y VE K++   +W              +  L   + Y 
Sbjct: 5881 TETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEYT 5940

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR+ A N+ G S P          K    P  P +   S  T  S TL W  P S+GGSP
Sbjct: 5941 FRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASNITETSATLNWKAPTSDGGSP 6000

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQ 1955
            ITNY IE +      WT       S     + +++   E  FR++A N  G   P+  S+
Sbjct: 6001 ITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAAVNKAGSGKPSVPSE 6060

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
            + + +     P  P+AP+ I  V +N V  SW  P  DGG+ ++ Y +  +D     W E
Sbjct: 6061 TFKAQPPYAAPEAPSAPV-IEEVTANSVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRWTE 6119

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            V +    T  F +  L E      R+ A N+ G  +P +S
Sbjct: 6120 VNRTPETT--FTVPKLKEGDAVQFRVTAVNKAGPGKPSQS 6157



 Score =  232 bits (567), Expect = 9e-59
 Identities = 218/913 (23%), Positives = 368/913 (40%), Gaps = 52/913 (5%)

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
            AG       ++  TA    +EPS     +     + P +     T    D    +T Y  
Sbjct: 3584 AGPGEASDASASFTAKAPFDEPSAPGVPKASN--ITPTSVTLSWTAPDSDGGSPITEYIL 3641

Query: 1233 KSVIEDTEKFTLIS--DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE---VVEFP 1287
            +S  + + KF+ ++   V   T  ++   E+ + ++  +  +    ++   E   V ++ 
Sbjct: 3642 ESKDKYSSKFSPVTRDTVTDLTFTVKNLKENGEYQFRVIAQNKAGPSEPSRETKVVAKYE 3701

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQA-FPQPNDE---WIVNSKIIKKCKHTKPSIDS-KS 1342
             ++        ++R S  ++ +D+   F     +   +I+  K  K  + T  S DS   
Sbjct: 3702 FEVPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIEKKE-KSGRWTPVSSDSVDG 3760

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICW 1401
             + T+K + + +   +++   N  G +   ++ V     P  PG+P + +I+ +S  + W
Sbjct: 3761 TTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTVLTAKPPGAPGRPEVSDINKTSATVTW 3820

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
                + G STI  Y+VE +E     W+ V  K I      + +L   + Y FR  A N +
Sbjct: 3821 KPSSSDGGSTITGYIVEKREKGRDRWVPVNRKPINAVTMKVTDLTEKTDYEFRVIAENRI 3880

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVPQPK--V 1513
                 SE +   K I ++    PT     K     P   + LT       GG P     +
Sbjct: 3881 GQGQPSEPSA--KFIAKSPFDVPTAPGAPKASDITPTS-LTLTWTPPTDDGGSPITNFII 3937

Query: 1514 TWY-RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             W  +   +    K                     ++ IA N  G+ E S    +  K  
Sbjct: 3938 EWKDKFSTRFTILKKDLFVELTFKVTGLKDKTEYTFRIIAENKEGQSEPSKETVVVAKYG 3997

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPP------EVIWYKNGNKLENDKEYNITTKEK 1626
              I  E    + K       T+V     PP      ++  Y    K ++ +   +T    
Sbjct: 3998 FDIPQEPSAPEVK---RLSPTSVELSWTPPRSDGGADITGYILEKKDKSGRWTPVTDSVD 4054

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             +   +K LK   + ++ + A N AG S       V  KP  P G   + ++ +  VT+ 
Sbjct: 4055 GTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVSLVAVKPPGPPGMPEVSDVDKNCVTLN 4114

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W PP  DGG  +  Y +EK E   + WI+V     +  T  +  L E  +Y FRVIA+N 
Sbjct: 4115 WTPPTSDGGSTIIGYTVEKREKGRS-WIRVNRTLVNETTMTVSDLVEKNDYEFRVIAENK 4173

Query: 1747 VGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
            VG  E    S   V K   DVP+          +   +  +TW P +++GGSPI  Y +E
Sbjct: 4174 VGPGEPSNPSIKFVAKAPFDVPAAPDAPEPSN-VTPTTATLTWTPPKRDGGSPITGYILE 4232

Query: 1806 IKQE-GKKWKXXXXXXXX--XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK- 1861
            +K     +W              ++ L   T YQFR+ A N+ G S P  S + + I K 
Sbjct: 4233 MKDRFATRWTQVNTDSMTEVTCTLKTLKEGTEYQFRVIAVNKAGQSKP--SAETVVIAKH 4290

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
                P  P    ++++T  S++L W  P+ NGGS +T Y IE K      W+ I  V   
Sbjct: 4291 PFDVPGAPSTPTITKATPNSISLAWRPPKVNGGSRVTGYYIEMKDEYRPRWSPINKVAIK 4350

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL--EIRMVG 1979
              ++ + ++ + ++  FR+ AEN  G   P+      L+  AT   P  AP   ++  + 
Sbjct: 4351 DTDYKVMDLTKNEKYYFRVKAENKAGQGKPS------LDTKATAKYPFDAPTIDDVSRIS 4404

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
                   W  P  DGGA + GY I  +D     W  V +  ++   F +++L E      
Sbjct: 4405 ETSAKIKWTPPSNDGGAEISGYIIEKKDRLAVKWSPVIEDTLDNTSFTVKNLREGEDVEF 4464

Query: 2040 RIYARNEIGLSEP 2052
            R+ A N+ G  +P
Sbjct: 4465 RVSAVNKAGTGKP 4477



 Score =  230 bits (563), Expect = 3e-58
 Identities = 136/440 (30%), Positives = 200/440 (45%), Gaps = 13/440 (2%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSS----VEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            ++  LK     ++ + A N AG S        ++K  D PS+P+    +++++  SVT+ 
Sbjct: 5633 KVTGLKDGQDCEFRVVAKNKAGASQPSSVATFSIKPPDAPSRPD----IKKVTENSVTLS 5688

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W PP  DGG  +T Y +E+ EPD + W+K         T+ +Q L    +Y FRVIA+N 
Sbjct: 5689 WSPPESDGGSPVTSYIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENK 5748

Query: 1747 VGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
             G   A E S+ ++ K   DVP           I   S  + W P   +GGSPI +Y VE
Sbjct: 5749 AGLGGASEASKSVIAKPPYDVPD-VPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVE 5807

Query: 1806 IKQE-GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
            +K + G +W           ++  L   + Y+F++ A N+ G   P  S   I       
Sbjct: 5808 MKDKFGVRWTSLGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYD 5867

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
             P  P     S  T  SVTL W+ P S+GGS IT YI+E K      W            
Sbjct: 5868 VPDAPEKPEPSSLTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTT 5927

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
              + +++E  E  FR+ AEN  G S P+E  +  + +K   VP  P +P E   +     
Sbjct: 5928 LTLNDLREGSEYTFRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSP-EASNITETSA 5986

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
              +W  P  DGG+P+  Y I  R+     W    + DV+   F +RDL   H Y  R+ A
Sbjct: 5987 TLNWKAPTSDGGSPITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAA 6046

Query: 2044 RNEIGLSEPLESDEPFKVIP 2063
             N+ G  +P    E FK  P
Sbjct: 6047 VNKAGSGKPSVPSETFKAQP 6066



 Score =  230 bits (562), Expect = 4e-58
 Identities = 196/700 (28%), Positives = 294/700 (42%), Gaps = 41/700 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            P  P  P++ +I  SS+ + W+ P + G ST+  Y+VE +E     W+ V    I +T  
Sbjct: 7175 PDAPSPPSVSDITPSSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTF 7234

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             + +L  +  Y FR  A N   +   SE +   +V K          +P           
Sbjct: 7235 KVNDLSEDRKYEFRVSAENAAGVGKPSEVS-LPRVAKSPYDAPSAPGRPTATNVDSTELV 7293

Query: 1499 IELTCIF--GGVPQPK-VTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAF 1553
            +E T     GG P    V   RD   L+ +K   +                 Y  + IA 
Sbjct: 7294 LEWTAPVADGGSPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAE 7353

Query: 1554 NDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP-----PEVIWY 1607
            N  G    S     I  KP       D  +  +V      +A +E  PP       V  Y
Sbjct: 7354 NKVGLGRPSDNTESIVAKP--PYDTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGY 7411

Query: 1608 KNGNKLENDKEY---NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTL 1660
                K +    +   N     +T+++ + +LK     ++ + A N AG    + S + T+
Sbjct: 7412 FVERKDQYSARWTRVNRVPVTETNMV-VGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTV 7470

Query: 1661 --KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
                 D PS P  P I   I+ +S T+ W  P  DGG  +T Y +E+ +P   RW     
Sbjct: 7471 IKDPVDAPSAPLEPTIA-SITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARW---TP 7526

Query: 1719 VDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXX 1776
            ++R  +T C I  L E  EY FRV+A N  G S     S+P V K+  DVP         
Sbjct: 7527 IERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPSKPQVT 7586

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINT 1833
              +   SV + W P   +GGSPI  Y V+ K+    +W              +  L+  +
Sbjct: 7587 E-VKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQKS 7645

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
             Y+FR+ A N+ G   P    + + +      PS P   VV++ T  SVTL+W  PES+G
Sbjct: 7646 EYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPP---VVTDFTKTSVTLQWNPPESDG 7702

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            GS IT Y++E K      W    +      E  ++++KE  +  FR+ A N  G+  P++
Sbjct: 7703 GSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSD 7762

Query: 1954 SQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
               +   K    VPSPP  P  I  + +  V  +W  P  DGG+P+ GY +   D   T 
Sbjct: 7763 GSELATAKSKFGVPSPPGEP-TISNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTR 7821

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            W+ V    +   K +I DL    +Y  RI A N  G S+P
Sbjct: 7822 WVPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKP 7861



 Score =  228 bits (557), Expect = 1e-57
 Identities = 146/462 (31%), Positives = 211/462 (45%), Gaps = 16/462 (3%)

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPVIMREISRESV 1683
            + I +L   +  ++ + A N AG       S  V  K+ +D P  P  P +  E +   +
Sbjct: 2277 LTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKAKLPFDAPGAPGKPQVT-EYNITKM 2335

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
            TI W PP  DGG  +T + +E+ E  ++RW++V        T  +  L E  EY FRVIA
Sbjct: 2336 TITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIVTGLTEGSEYQFRVIA 2395

Query: 1744 QNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            +NP G   A E   +   K   D PS           D   + +TW   + +GGSPI  Y
Sbjct: 2396 ENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSA-DKTQMELTWAVPDSDGGSPITGY 2454

Query: 1803 KVEIKQEGKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             ++ K+   KW            A I+ L     Y+FR+ A N  GT  P++      I 
Sbjct: 2455 IIQKKENTGKWTQSLKTTTTETTATIKSLIEKKEYEFRVAAVNLAGTG-PFSEPSDYQIA 2513

Query: 1861 KT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919
            K     P  P    + E  S S+T+ WT PE++GGSP+T Y++E +      WTK+    
Sbjct: 2514 KAPYDVPGPPGKPTILEVDSTSMTITWTPPETDGGSPVTGYVVEKRDRVSSRWTKVKETS 2573

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978
                 + I ++KE ++  FR+SAEN  GV  P+E S   R +    VP PP  P +I  V
Sbjct: 2574 IEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPPYDVPGPPGIP-DISDV 2632

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD-VNTLKFNIRDLSENHTY 2037
              N +  +W  P  DGGA +LGY +   D  +  W +  K D V  L   + DL+E   Y
Sbjct: 2633 DKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHKEDLVTELTLTVYDLTEGTNY 2692

Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
            M R+ A N  G+ E   + +P K  P         P   T V
Sbjct: 2693 MFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPPPPTPTHV 2734



 Score =  227 bits (556), Expect = 2e-57
 Identities = 181/705 (25%), Positives = 296/705 (41%), Gaps = 33/705 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
            P  P  P I E+ ++S+ + W+ P   G S II YVVE ++  +  W  V    +T  ++
Sbjct: 6071 PEAPSAPVIEEVTANSVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRWTEVNRTPETTFTV 6130

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-----IKETKIQSPTVEKPLKNITTE- 1494
              LK   + +FR  AVN+      S+++    +     + E   Q   VE    +IT   
Sbjct: 6131 PKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVEVDAVSITVRW 6190

Query: 1495 --PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
              P  D   + I   + + K  +    K++ T +++                   ++ IA
Sbjct: 6191 SAPKNDGG-SRITNYILEMKEQFSSFWKRVSTKESS---ELTYQVTGLKENQTLEFRVIA 6246

Query: 1553 FNDHGEVETSCVVG-IQQKPVITISNE----DIK--QKHKVGDEWLVTAVIEGIPPPEVI 1605
             N  GE + S V G    K   T+ +     D+   +   +   W  +    G P    +
Sbjct: 6247 VNKAGEGKPSSVGGPFTTKATYTVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYV 6306

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-D 1664
              K           N     +TS++ + +L+      + + A N AG S      K Y  
Sbjct: 6307 LEKCDVSTGRWVPVNRVPLRETSLV-VDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIA 6365

Query: 1665 KP--SKPEGPVI--MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DV 1719
            KP    P+ P    +  I  + +T+ W PP  DGG  +  Y IEK +  + RW +   + 
Sbjct: 6366 KPPYGLPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRET 6425

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXX 1778
              D++ Y +++L E  E  FRV A+N  G     E+   VI K+  DVPS          
Sbjct: 6426 IHDMQ-YTLRELTEGGEVEFRVAAENKAGVGPFSETTGTVIAKSPFDVPS-APGTPKISD 6483

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA--RIQKLSINTTYQ 1836
            I   S+ +TW P   +GG+ I ++ +E++    +W              +  LS   +Y+
Sbjct: 6484 ITGTSLVLTWTPPSSDGGTEITNFIIELRDRYGRWTRVNRTQVLKTGFNVMNLSEGDSYE 6543

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR+ A N++G   P  S  K+T     + P+ P    +S  T+ S TL W+ P  +GGS 
Sbjct: 6544 FRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQISNVTADSATLTWSPPRDDGGSS 6603

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955
            IT Y IE K      WT++     +  +  +  +   +E  FR+ A+N  G S P+E ++
Sbjct: 6604 ITGYFIEKKDKFSPRWTRVNHDAVTDTKFTVPALVPGEEYQFRVVAQNKAGASKPSEPTE 6663

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
            S  +      P  P AP    +  + + +T W  P  DGG+ + GY +  +D     W  
Sbjct: 6664 STLVRSPFNEPGAPGAPETSNVTETTLTLT-WTPPFSDGGSRITGYYVEKKDRMSLRWSP 6722

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            V        K  +  L+E   Y  R+ A N+ G S+P     P K
Sbjct: 6723 VNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVK 6767



 Score =  226 bits (553), Expect = 5e-57
 Identities = 135/437 (30%), Positives = 200/437 (45%), Gaps = 11/437 (2%)

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
            T + TS   +K L+     ++ + A N AGT        +  KP  P G      I + S
Sbjct: 4445 TLDNTS-FTVKNLREGEDVEFRVSAVNKAGTGKPSSIATLAAKPPGPPGVPEASNIDKIS 4503

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
             T+ W PP  DGG ++T Y +EK E   +RW+KV        T  +  L E   Y FRV 
Sbjct: 4504 ATLTWTPPESDGGSKVTGYIVEKRERGLDRWMKVNRAPVKDVTLKVLDLTEKKHYEFRVT 4563

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            A+N  G  E  +S   + K   DVP           I   S  ++W P   +GGSPI  Y
Sbjct: 4564 AENKAGLGEPSDSVSFIAKPPYDVPG-APSTPVASDISPTSATLSWSPPYSDGGSPITSY 4622

Query: 1803 KVEIKQE-GKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             +E+K     +W K          ++  L  N  YQFR+ A N+ G   P +    +T  
Sbjct: 4623 TIEMKDRFSSRWTKAKDMVTEETFQLNSLKENNEYQFRVIAENKAGPGEP-SPTVNVTAK 4681

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
                 P  P    V  ++  SV L W +P+S+GGS I  YIIE K VKG+ WT++ T   
Sbjct: 4682 YEFDTPQAPAEPDVRRTSPTSVELSWVKPKSDGGSKIKGYIIE-KKVKGEPWTQVTTDTV 4740

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
                  +  + E +++ FRISA N  G   P+ +  +  +     P PP  P E+  V  
Sbjct: 4741 DGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVVIAFKP----PGPPGTP-EVSDVDK 4795

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
              V  +W  P+ DGG+ ++GY +  R+  +  W+ + +  V  +  +I DL E + Y  R
Sbjct: 4796 TSVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREVTMSITDLVEKNEYEFR 4855

Query: 2041 IYARNEIGLSEPLESDE 2057
            + A N++G  EP    E
Sbjct: 4856 VIAENKVGPGEPSSPSE 4872



 Score =  224 bits (548), Expect = 2e-56
 Identities = 174/704 (24%), Positives = 288/704 (40%), Gaps = 36/704 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436
            D+P PP  P    +D +SI++ W  P++ G S +  Y++E ++    +W  V    I + 
Sbjct: 2721 DEPGPPPPPTPTHVDRTSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEI 2780

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
              ++  L  ++ Y FR  AVN+      S  ++  K      +       P+ +  TE +
Sbjct: 2781 SFTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAP-STPVPSDITETS 2839

Query: 1497 EDIELT--CIFGGVPQPK-VTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCI 1551
              +E +     GG    + +   +D    +  KA  T  +                ++ I
Sbjct: 2840 VHLEWSPPSNNGGAEITEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVI 2899

Query: 1552 AFNDHGEVETS--CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----V 1604
            A N  G    S  C   + + P       D   K    D    +  +   PPP      +
Sbjct: 2900 AVNPAGPGSPSDACKPFVAKPPYDV---PDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPI 2956

Query: 1605 IWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTSS----VEV 1658
              Y    K +    +   T+E  S   + + +LK     ++ + A N AG S     + V
Sbjct: 2957 TGYTVEMKDKFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKPSPELHV 3016

Query: 1659 TLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
            T K  ++ P  P    + RE S  S T++W PP  DGG E+T Y +EK E  + RW  V 
Sbjct: 3017 TAKYPFETPQAPTIDNVTRE-SPTSATVKWSPPKSDGGSEITGYVLEKKEKMSPRWSPVI 3075

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
            + + +  ++ ++ L +     FRV A N  G       +P  + T    P          
Sbjct: 3076 ESETET-SFTVKGLPDGENVEFRVSAVNKAG-----TGKPSQVATLSAKPPGAPDAPEVS 3129

Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX--XXARIQKLSINTT 1834
             ID  S  + W     +GGS I  Y +E +++G+ +W             ++  L+    
Sbjct: 3130 DIDRTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQ 3189

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y+FR+ A N++G   P     + T       P  P +   S+ T  S TL W  P+S+GG
Sbjct: 3190 YEFRVIAENKVGPGEPSNPSARFTAKAPFDEPEAPYSLAASDITPTSATLSWLPPDSDGG 3249

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
            SPI  Y +E K      WTK+           + N++E +E ++R+ AEN  G S P+  
Sbjct: 3250 SPILGYTLETKDRFSSRWTKVNKGLLQETSFKVTNLEENNEYVYRVIAENKAGPSKPSNE 3309

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
                 +     P  P   +      ++ V+T W  P +DGG+P+ GY + +++   T W 
Sbjct: 3310 CKFIAKHQFETPEAPGNVVAKDTTPTSTVIT-WREPSFDGGSPITGYTVEMKEPYSTRWT 3368

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               K  +    F ++ L EN  Y  R+ A N  G  +P     P
Sbjct: 3369 PANKEPIEETTFLVKRLKENENYQFRVVAHNLAGPGKPKAPKPP 3412



 Score =  220 bits (538), Expect = 3e-55
 Identities = 185/725 (25%), Positives = 290/725 (40%), Gaps = 40/725 (5%)

Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
            +D +M     D P PP KP    I+ ++I I W  PEN G S +  Y+VE  E     W+
Sbjct: 2206 SDNKMAKAPYDVPGPPSKPTTENINKTTITITWTPPENDGGSPVTGYIVEKCEGARGRWV 2265

Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
                  +T+   +I +L   + Y+FR  A N   +      ++  K     K+       
Sbjct: 2266 KCNKDLVTELTLTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKA----KLPFDAPGA 2321

Query: 1487 PLKNITTEPNEDIELTCIF------GGVPQPK-VTWYRDGKKLKTAKATYENRXXXXXXX 1539
            P K   TE N   ++T  +      GG P    V   ++    +  + T E         
Sbjct: 2322 PGKPQVTEYNIT-KMTITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIV 2380

Query: 1540 XXXXXXXXY--KCIAFNDHGEVETSCVVGIQQKPV-----ITISNEDIKQKHKVGDE--W 1590
                    Y  + IA N  G    S    +Q+  +           ++    K   E  W
Sbjct: 2381 TGLTEGSEYQFRVIAENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSADKTQMELTW 2440

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
             V     G P    I  K  N  +  +    TT E T+ I  K L      ++ + A N 
Sbjct: 2441 AVPDSDGGSPITGYIIQKKENTGKWTQSLKTTTTETTATI--KSLIEKKEYEFRVAAVNL 2498

Query: 1651 AGT------SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            AGT      S  ++    YD P  P  P I+ E+   S+TI W PP  DGG  +T Y +E
Sbjct: 2499 AGTGPFSEPSDYQIAKAPYDVPGPPGKPTIL-EVDSTSMTITWTPPETDGGSPVTGYVVE 2557

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTA 1763
            K +  ++RW KV +   +   Y I  L E  +Y FRV A+N  G  +  E S+    K  
Sbjct: 2558 KRDRVSSRWTKVKETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPP 2617

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXX--- 1819
             DVP           +D   + +TW P   +GG+ I+ Y VE    + K+W         
Sbjct: 2618 YDVPGPPGIPDISD-VDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHKEDLV 2676

Query: 1820 XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                  +  L+  T Y FR+ A N  G      +            P  P     +    
Sbjct: 2677 TELTLTVYDLTEGTNYMFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPPPPTPTHVDR 2736

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
             S+ L W+ P+ +GGS +T YI+E +      WTK+           +  + E     FR
Sbjct: 2737 TSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEISFTVTGLTEDAIYDFR 2796

Query: 1940 ISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
            +SA N  G   P+  S +++ +    VP  P+ P+   +  +++ +  W  P  +GGA +
Sbjct: 2797 VSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETSVHL-EWSPPSNNGGAEI 2855

Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              Y +  +D   + W + G+   +T+   ++DL E + Y  R+ A N  G   P ++ +P
Sbjct: 2856 TEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKP 2915

Query: 2059 FKVIP 2063
            F   P
Sbjct: 2916 FVAKP 2920



 Score =  219 bits (535), Expect = 7e-55
 Identities = 175/701 (24%), Positives = 284/701 (40%), Gaps = 47/701 (6%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436
            D P  PGKP   ++  +S+ + W  P + G S I  Y VE ++  +T W       I++T
Sbjct: 2923 DVPDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPITGYTVEMKDKFSTRWTKATRELISET 2982

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               + +LK    Y+FR  A N+   S  S              Q+PT++   +   T   
Sbjct: 2983 TVVLPDLKEKEEYQFRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRESPTSAT 3042

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCI 1551
                     GG    ++T Y   KK K +         E                 ++  
Sbjct: 3043 VKWSPPKSDGG---SEITGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVS 3099

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKN 1609
            A N  G  + S V  +  KP       ++    +      W V ++  G     +  Y  
Sbjct: 3100 AVNKAGTGKPSQVATLSAKPPGAPDAPEVSDIDRTSATVIWTVPSLDGG---STITGYTI 3156

Query: 1610 GNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV 1662
              + +    +    K   K + +++ +L   +  ++ + A N  G       S   T K 
Sbjct: 3157 ERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQYEFRVIAENKVGPGEPSNPSARFTAKA 3216

Query: 1663 -YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
             +D+P  P   +   +I+  S T+ W PP  DGG  +  Y +E  +  ++RW KV     
Sbjct: 3217 PFDEPEAPYS-LAASDITPTSATLSWLPPDSDGGSPILGYTLETKDRFSSRWTKVNKGLL 3275

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
               ++ +  L EN EY++RVIA+N  G S+       + K   + P              
Sbjct: 3276 QETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKDTTPT 3335

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFR 1838
             +V ITW     +GGSPI  Y VE+K+    +W              +++L  N  YQFR
Sbjct: 3336 STV-ITWREPSFDGGSPITGYTVEMKEPYSTRWTPANKEPIEETTFLVKRLKENENYQFR 3394

Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            + A N  G   P          K   PP+ P    V   +  SV L W+ P S+GGS +T
Sbjct: 3395 VVAHNLAGPGKP----------KAPKPPTPPE---VKRLSPTSVQLNWSAPTSDGGSEVT 3441

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             YI+E K   G+ WT + +         ++ +KE +++ FR+SA N  G   P+E   + 
Sbjct: 3442 AYIVEKKDKSGR-WTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIA 3500

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
                A  PS P+ P E+  +     + +W  P+ DGG+ + GY +  R+  +  W+ V +
Sbjct: 3501 ----AKPPSAPSKP-EVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNR 3555

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
              V      + DL E + Y  R+ A N  G  E  ++   F
Sbjct: 3556 KPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASF 3596



 Score =  210 bits (513), Expect = 3e-52
 Identities = 191/764 (25%), Positives = 308/764 (40%), Gaps = 43/764 (5%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-P-SPPGKPNILEIDSSSIN 1398
            K     +  +   +   ++++ EN  G     ++     K P   P   ++  I  +S  
Sbjct: 4350 KDTDYKVMDLTKNEKYYFRVKAENKAGQGKPSLDTKATAKYPFDAPTIDDVSRISETSAK 4409

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAV 1456
            I W  P N G + I  Y++E ++    +W  V   T   TS  ++NL+      FR  AV
Sbjct: 4410 IKWTPPSNDGGAEISGYIIEKKDRLAVKWSPVIEDTLDNTSFTVKNLREGEDVEFRVSAV 4469

Query: 1457 NEVDISDASE-TTEYYKVIKETKI-QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            N+      S   T   K      + ++  ++K    +T  P E    + + G + + +  
Sbjct: 4470 NKAGTGKPSSIATLAAKPPGPPGVPEASNIDKISATLTWTPPESDGGSKVTGYIVEKRER 4529

Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
                 + +K  +A  ++                ++  A N  G  E S  V    KP   
Sbjct: 4530 GL--DRWMKVNRAPVKD-VTLKVLDLTEKKHYEFRVTAENKAGLGEPSDSVSFIAKPPYD 4586

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK------LE-NDKEYNITTKEKT 1627
            +            D    +A +   PP     Y +G        +E  D+  +  TK K 
Sbjct: 4587 VPGAP--STPVASDISPTSATLSWSPP-----YSDGGSPITSYTIEMKDRFSSRWTKAKD 4639

Query: 1628 SV----IRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV-YDKPSKPEGPVIMREI 1678
             V     ++  LK ++  ++ + A N AG    + +V VT K  +D P  P  P + R  
Sbjct: 4640 MVTEETFQLNSLKENNEYQFRVIAENKAGPGEPSPTVNVTAKYEFDTPQAPAEPDV-RRT 4698

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            S  SV + W  P  DGG ++  Y IEK +     W +V     D  ++ ++ L E+ +  
Sbjct: 4699 SPTSVELSWVKPKSDGGSKIKGYIIEK-KVKGEPWTQVTTDTVDGTSFTVRGLPEDEDVE 4757

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            FR+ A N  G      +  I  K     P           +D  SV +TW P + +GGS 
Sbjct: 4758 FRISAVNKAGAGSPSNTVVIAFK-----PPGPPGTPEVSDVDKTSVTLTWTPPKLDGGSK 4812

Query: 1799 IIDYKVEIKQEGK-KWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            +I Y VE +++G+ +W              I  L     Y+FR+ A N++G   P +  +
Sbjct: 4813 VIGYIVEKREKGRDRWVRINRSPVREVTMSITDLVEKNEYEFRVIAENKVGPGEPSSPSE 4872

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
            +I        PS P++   ++ T  SVTL W+ P SNGGSPI  Y IE K      WT +
Sbjct: 4873 RIVAKAPYEVPSPPKSLKATDLTPISVTLNWSAPLSNGGSPIVGYTIEMKDKFSTRWTNV 4932

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
                 +     + N+KEK++  FR+ A N  G   P+E  SV  +     P  P+ P  I
Sbjct: 4933 SEHMVTTLSLNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFPFNAPEAPSPP-SI 4991

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              +    V  +W  P  DGG  + GY I  +D     W  V K  ++   F I+ L E  
Sbjct: 4992 ERISPTSVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIIDDTNFTIKGLKEGE 5051

Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
                R+ A N+ G  +P ++     + PG          +QT V
Sbjct: 5052 EAEFRVVAVNKAGSGKPSQTTVLAALPPGPPESPSISDVKQTSV 5095



 Score =  209 bits (510), Expect = 7e-52
 Identities = 181/746 (24%), Positives = 298/746 (39%), Gaps = 46/746 (6%)

Query: 1347 IKKVENTDAGIYKLRLENNCG---HADVEMNVTI---LDKPSPPGKPNILEIDSSSINIC 1400
            +  +   D+  +++  EN  G    +D    VT      +P+ P +P I  + + S  + 
Sbjct: 6533 VMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQISNVTADSATLT 6592

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
            W  P + G S+I  Y +E ++  +  W  V +  +T T+ ++  L     Y+FR  A N+
Sbjct: 6593 WSPPRDDGGSSITGYFIEKKDKFSPRWTRVNHDAVTDTKFTVPALVPGEEYQFRVVAQNK 6652

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-- 1516
               S  SE TE   +++    +      P  +  TE    +  T  F      ++T Y  
Sbjct: 6653 AGASKPSEPTE-STLVRSPFNEPGAPGAPETSNVTETTLTLTWTPPFSD-GGSRITGYYV 6710

Query: 1517 --RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQQKPV 1572
              +D   L+ +   +E+                Y  + +A ND G  + S        PV
Sbjct: 6711 EKKDRMSLRWSPVNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRSKPSA----PSYPV 6766

Query: 1573 ITISNEDIKQ---KHKVGDEWLVTAVIEGIPPPE------VIWYKNGNKLENDKEYNITT 1623
               S  D+        + D       +   PP        + +     +  + +   I+ 
Sbjct: 6767 KAKSPFDLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISR 6826

Query: 1624 KEKT-SVIRIKELKRSHSSKYTIEASNTAGTSSV-EVT-----LKVYDKPSKPEGPVIMR 1676
             + T +   +  LK  +  ++ + A N  G     E T      + Y+ PS P+    + 
Sbjct: 6827 FDFTETTFSVTGLKDGNDYEFRVAAKNKIGIGKFSEPTRPTKAKEPYESPSTPD----VS 6882

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
             I+ ES+T+ W  P  DGG  +T Y IEK EP  + W  V        +  +  L +  E
Sbjct: 6883 NITGESMTLNWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAE 6942

Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            Y FRVIA+N  G     + + P   K     P           +   ++ I+W P   +G
Sbjct: 6943 YEFRVIAENKAGLGRPSQVTHPFTAKPPYTTPG-IPDQPEVEDVTATTITISWSPPSYDG 7001

Query: 1796 GSPIIDYKVEIKQEG-KKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
            GS I  Y +E K +   +W K             +L   + YQFR+ A N+ G       
Sbjct: 7002 GSKITGYTIESKSDATMRWVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKP 7061

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
               +T      PP  P    V   T  S  L W+ P  +GGSPIT Y+I+ K      W 
Sbjct: 7062 SRPVTCKPPYDPPPPPDAPDVYNITPTSAALTWSTPRQDGGSPITGYVIDKKDKYSTRWV 7121

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAP 1972
            K   V     +  I+ ++  ++  FR+SA N  GV  P+   +    +    VP  P+ P
Sbjct: 7122 KADEVPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPDAPSPP 7181

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
                +  S++ + SW  P  DGG+ + GY +  R+     W+ V +  +    F + DLS
Sbjct: 7182 SVSDITPSSMTL-SWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLS 7240

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEP 2058
            E+  Y  R+ A N  G+ +P E   P
Sbjct: 7241 EDRKYEFRVSAENAAGVGKPSEVSLP 7266



 Score =  205 bits (501), Expect = 9e-51
 Identities = 122/422 (28%), Positives = 200/422 (47%), Gaps = 16/422 (3%)

Query: 1642 KYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
            ++ + A N AG    + SV +T ++   P  PE    +   S +SV + W PP + GG  
Sbjct: 5348 EFHVIAINKAGEGKPSPSVSLTFRLPGPPGTPE----VYNPSDKSVDLRWTPPTEQGGTR 5403

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
            +  Y IEK E   + W+++         Y +  L  NC + FRV A+N  G     + SE
Sbjct: 5404 IIGYFIEKCEVGKDNWVRINRSSIREANYVVGDLTLNCRFKFRVCAENRAGVGPPSDYSE 5463

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKX 1815
             ++IK   DVP           + N+S+ I+W P   +GGS + +Y +E K+    KW  
Sbjct: 5464 SVLIKLPYDVPESPDTPKISD-VTNDSMVISWQPPYSDGGSKVTEYIIEKKEPYSSKWVP 5522

Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                     +I  L  N  Y+FR+ A N+ G S                 PSQP +  ++
Sbjct: 5523 VTKTRDLSYKITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVPSQPHSLKIA 5582

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
            + +  S+TL+W+EP+S+GG  ++ YIIE K      WT +     S  +  +  +K+  +
Sbjct: 5583 DVSPTSLTLEWSEPDSDGGDNVSGYIIEKKDRFSPRWTPVNQTAISDTKFKVTGLKDGQD 5642

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              FR+ A+N  G S P+   +  ++     P  P+ P +I+ V  N V  SW  PE DGG
Sbjct: 5643 CEFRVVAKNKAGASQPSSVATFSIKP----PDAPSRP-DIKKVTENSVTLSWSPPESDGG 5697

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            +P+  Y +  R+  +  W++  +  +    F ++DL+  H Y  R+ A N+ GL    E+
Sbjct: 5698 SPVTSYIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEA 5757

Query: 2056 DE 2057
             +
Sbjct: 5758 SK 5759



 Score =  205 bits (500), Expect = 1e-50
 Identities = 194/736 (26%), Positives = 307/736 (41%), Gaps = 49/736 (6%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSS 1395
            +  S  +  +E  +  +Y++  EN  G +        + K     P  PG     +   +
Sbjct: 3276 QETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKDTTPT 3335

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453
            S  I W EP   G S I  Y VE +E  +T W       I +T   ++ LK N +Y+FR 
Sbjct: 3336 STVITWREPSFDGGSPITGYTVEMKEPYSTRWTPANKEPIEETTFLVKRLKENENYQFRV 3395

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
             A N   ++   +        K  K  +P   K L   + + N     +   GG    +V
Sbjct: 3396 VAHN---LAGPGKP-------KAPKPPTPPEVKRLSPTSVQLNWSAPTS--DGG---SEV 3440

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXX-----XXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            T Y   KK K+ + T                        ++  A N  G  + S V  I 
Sbjct: 3441 TAYIVEKKDKSGRWTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIA 3500

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT- 1627
             KP    S  ++    K       TA           +     +   D+   +  K  T 
Sbjct: 3501 AKPPSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTE 3560

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKPSKPEGPVIMREISRE 1681
            + +++ +L   ++ ++ + A N AG      +S   T K  +D+PS P  P     I+  
Sbjct: 3561 TTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASFTAKAPFDEPSAPGVPK-ASNITPT 3619

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFR 1740
            SVT+ W  P  DGG  +T+Y +E  +  ++++  V  D   D+ T+ ++ L EN EY FR
Sbjct: 3620 SVTLSWTAPDSDGGSPITEYILESKDKYSSKFSPVTRDTVTDL-TFTVKNLKENGEYQFR 3678

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            VIAQN  G SE      +V K   +VP           +   S+ + W P   +GGS I 
Sbjct: 3679 VIAQNKAGPSEPSRETKVVAKYEFEVPQ-APSAPEVRRLSPTSIQLDWTPPFADGGSDIT 3737

Query: 1801 DYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             Y +E K++  +W              ++ L  +   +FRI A N+ G S P     ++T
Sbjct: 3738 GYIIEKKEKSGRWTPVSSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKP----SQVT 3793

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVT 1917
            +  T  PP  P    VS+    S T+ W    S+GGS IT YI+E K  KG+  W  +  
Sbjct: 3794 V-LTAKPPGAPGRPEVSDINKTSATVTWKPSSSDGGSTITGYIVE-KREKGRDRWVPVNR 3851

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIR 1976
               +     + ++ EK +  FR+ AEN +G   P+E  +  + K    VP+ P AP    
Sbjct: 3852 KPINAVTMKVTDLTEKTDYEFRVIAENRIGQGQPSEPSAKFIAKSPFDVPTAPGAPKASD 3911

Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
            +  +++ +T W  P  DGG+P+  + I  +D   T +  + K     L F +  L +   
Sbjct: 3912 ITPTSLTLT-WTPPTDDGGSPITNFIIEWKDKFSTRFTILKKDLFVELTFKVTGLKDKTE 3970

Query: 2037 YMIRIYARNEIGLSEP 2052
            Y  RI A N+ G SEP
Sbjct: 3971 YTFRIIAENKEGQSEP 3986



 Score =  205 bits (500), Expect = 1e-50
 Identities = 128/444 (28%), Positives = 205/444 (46%), Gaps = 18/444 (4%)

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEV-----TLKV-YDKPSKPEGPVIMREISR 1680
            T+   IK L+  +  ++ + A N AG           T K  Y  P  P  P +  +I+ 
Sbjct: 7130 TTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPDAPSPPSVS-DITP 7188

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
             S+T+ W+PP  DGG  +T Y +EK E    RW+ V        T+ +  L+E+ +Y FR
Sbjct: 7189 SSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLSEDRKYEFR 7248

Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            V A+N  G  +  E S P V K+  D PS          +D+  + + W     +GGSPI
Sbjct: 7249 VSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATN-VDSTELVLEWTAPVADGGSPI 7307

Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
             +Y +E + + G +W             ++  L  N  YQFR+ A N++G   P  + + 
Sbjct: 7308 TNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAENKVGLGRPSDNTES 7367

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            I        P  P +  V+ +T+ S +L+W+ P S+GGSP+T Y +E K      WT++ 
Sbjct: 7368 IVAKPPYDTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVN 7427

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE-- 1974
             V  +     + ++KE  +  FR+ AEN  G+   ++S    + K       P+APLE  
Sbjct: 7428 RVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPV--DAPSAPLEPT 7485

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
            I  + ++    +W  P  DGG+ + GY +  +D     W  + +      K  I  L E 
Sbjct: 7486 IASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPIERCTDTNCK--ISGLKEG 7543

Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058
            + Y  R+ A N+ G S P    +P
Sbjct: 7544 NEYQFRVVATNKAGQSAPSNPSQP 7567



 Score =  204 bits (497), Expect = 3e-50
 Identities = 174/691 (25%), Positives = 276/691 (39%), Gaps = 30/691 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            PSPPG+P I  I + S+ + W  P + G S +  Y VE  +  +T W+ V +  I  T+ 
Sbjct: 7776 PSPPGEPTISNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTRWVPVNSHPIKDTKM 7835

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             I +L    SY+FR  A N    S  +  T+   +    K+ +    K    +       
Sbjct: 7836 DIHDLPATGSYQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDT---YKYHDTMVVRVGAT 7892

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
              L   F   P+P V W +DG  L+ +      T +                 +K    N
Sbjct: 7893 FNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSN 7952

Query: 1555 DHGEVETSCVVGI---QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
              G    +  V +    ++P   +  +DI     +   W   A   G P    I  +   
Sbjct: 7953 TAGSDAITIRVQVLDRPEQPRGPLVAKDIGST-DLFLSWKEPADTGGSPITHYIIER--R 8009

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDK 1665
            + +      +TT+   + +R+  L+   S  + + A N  G S     + T+K+   YD 
Sbjct: 8010 EEDRTSWTRLTTRALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDV 8069

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P  P  P++   ++ +SVT+EW  P  DGG  ++ Y IEK E  +N W KV  V   V +
Sbjct: 8070 PEAPSKPLV-TNVTSDSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTS 8128

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
            + I +L    EY FRV A+N  G   A   S PI  +    +P                 
Sbjct: 8129 HRIPRLMRGEEYEFRVSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEPIMAKVGES 8188

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
            +    P      +P + +  + +                + I   ++      R Y  N 
Sbjct: 8189 FRIEVP-YTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGGR-YTINL 8246

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
              T+   + D ++ +     PP  P     VSEST   VTL W+ P  +GGS I  Y+++
Sbjct: 8247 KNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSEST---VTLSWSPPSDDGGSRIFTYVVQ 8303

Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
             +      W  +         + +  +KE  +  FR+ AEN  G S P E QS+  +   
Sbjct: 8304 KRGEIETKWKHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITPQGQY 8363

Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
             VP PP+AP    ++G ++ +  W  P  DGGAP+ GY + +R  T   W++        
Sbjct: 8364 NVPDPPSAPKVTNIIGDSVTV-GWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLTPTPD 8422

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            + F    L     Y  R+ A N  G   P E
Sbjct: 8423 MTFRASRLIRGTEYEFRVCAVNRAGTGRPGE 8453



 Score =  200 bits (487), Expect = 4e-49
 Identities = 132/440 (30%), Positives = 201/440 (45%), Gaps = 15/440 (3%)

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPSKPEGPVIMREISRESV 1683
            E TS   +K LK     ++ + A N AGT    EVT+     PS P  P +  +I + S 
Sbjct: 3463 EDTS-FTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIAAKPPSAPSKPEVT-DIQKTSA 3520

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             + W  P +DGG ++T Y +EK E   ++W++V        T  +  L E   Y FRVIA
Sbjct: 3521 VVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTETTMKVPDLVEKNNYEFRVIA 3580

Query: 1744 QNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            +N  G  EA + S     K   D PS          I   SV ++W   + +GGSPI +Y
Sbjct: 3581 ENRAGPGEASDASASFTAKAPFDEPS-APGVPKASNITPTSVTLSWTAPDSDGGSPITEY 3639

Query: 1803 KVEIKQE-GKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
             +E K +   K+              ++ L  N  YQFR+ A+N+ G S P + + K+  
Sbjct: 3640 ILESKDKYSSKFSPVTRDTVTDLTFTVKNLKENGEYQFRVIAQNKAGPSEP-SRETKVVA 3698

Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919
                  P  P    V   +  S+ L WT P ++GGS IT YIIE K   G+ WT + +  
Sbjct: 3699 KYEFEVPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIEKKEKSGR-WTPVSSDS 3757

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
                   ++ + + +++ FRISA N  G S P++   +     A  P  P  P E+  + 
Sbjct: 3758 VDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTVLT----AKPPGAPGRP-EVSDIN 3812

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
                  +W     DGG+ + GY +  R+  +  W+ V +  +N +   + DL+E   Y  
Sbjct: 3813 KTSATVTWKPSSSDGGSTITGYIVEKREKGRDRWVPVNRKPINAVTMKVTDLTEKTDYEF 3872

Query: 2040 RIYARNEIGLSEPLESDEPF 2059
            R+ A N IG  +P E    F
Sbjct: 3873 RVIAENRIGQGQPSEPSAKF 3892



 Score =  199 bits (485), Expect = 8e-49
 Identities = 125/430 (29%), Positives = 200/430 (46%), Gaps = 18/430 (4%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEV---TLKV---YDKPSKPEGPVIMREISRESVTI 1685
            +++L+  H   + + A N AG+    V   T K    Y  P  P  PVI  E++  SV +
Sbjct: 6031 VRDLRAGHEYSFRVAAVNKAGSGKPSVPSETFKAQPPYAAPEAPSAPVI-EEVTANSVKL 6089

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQ 1744
             W+PP  DGG  +  Y +EK +  + RW    +V+R  ET + + KL E     FRV A 
Sbjct: 6090 SWEPPRLDGGSHIIDYVVEKKDAFSIRW---TEVNRTPETTFTVPKLKEGDAVQFRVTAV 6146

Query: 1745 NPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N  G  +  +S   + +K    VP           +D  S+ + W   + +GGS I +Y 
Sbjct: 6147 NKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVE-VDAVSITVRWSAPKNDGGSRITNYI 6205

Query: 1804 VEIKQEGKK-WKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
            +E+K++    WK            Q   +  N T +FR+ A N+ G   P +     T  
Sbjct: 6206 LEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVNKAGEGKPSSVGGPFTTK 6265

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
             T T PS P    VS   + S+T+ WT+  S+GGSPIT Y++E   V    W  +  V  
Sbjct: 6266 ATYTVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYVLEKCDVSTGRWVPVNRVPL 6325

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVG 1979
                  ++ ++EK E  FR+ A N  G S P+E     + K    +P  P  P +I  + 
Sbjct: 6326 RETSLVVDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIAKPPYGLPDAPAKP-DITNID 6384

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
            +  +  +W  P  DGG+P++GY I  +D     W    +  ++ +++ +R+L+E      
Sbjct: 6385 AKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRETIHDMQYTLRELTEGGEVEF 6444

Query: 2040 RIYARNEIGL 2049
            R+ A N+ G+
Sbjct: 6445 RVAAENKAGV 6454



 Score =  198 bits (484), Expect = 1e-48
 Identities = 128/440 (29%), Positives = 191/440 (43%), Gaps = 17/440 (3%)

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAG-------TSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            +  ++  LK +   ++ + A N  G       T S+ V    YD P  PE  V +   + 
Sbjct: 7333 TTFKVTGLKPNDEYQFRVIAENKVGLGRPSDNTESI-VAKPPYDTPDAPES-VQVTGTTA 7390

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
             S ++EW PP  DGG  +T Y +E+ +  + RW +V  V        +  L E  +Y FR
Sbjct: 7391 SSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVNRVPVTETNMVVGDLKEGLQYQFR 7450

Query: 1741 VIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            V A+N  G   + +S +P VIK  +D PS          I  +S  +TW    ++GGS +
Sbjct: 7451 VCAENRAGIGRSSDSTKPTVIKDPVDAPSAPLEPTIAS-ITADSATLTWIAPSRDGGSAV 7509

Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
              Y VE K     +W           +I  L     YQFR+ A N+ G S P        
Sbjct: 7510 TGYIVERKDPYTARWTPIERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKV 7569

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
                   P  P    V+E  + SVTLKW  P S+GGSPIT Y+++ K      WT + T 
Sbjct: 7570 AKSPYDVPEAPSKPQVTEVKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTT 7629

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977
                    +  + +K E  FR+ A N  G   P+E + SV ++     PSPP     +  
Sbjct: 7630 PVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPPV----VTD 7685

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
                 V   W  PE DGG+ + GY +  ++     W       +   +F ++DL E   Y
Sbjct: 7686 FTKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQY 7745

Query: 2038 MIRIYARNEIGLSEPLESDE 2057
              R+ A N+ G+  P +  E
Sbjct: 7746 EFRVMALNKAGIGPPSDGSE 7765



 Score =  196 bits (477), Expect = 7e-48
 Identities = 130/451 (28%), Positives = 201/451 (44%), Gaps = 19/451 (4%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPV 1673
            N  + E T  +++  L      ++ + A N AG S     S  V  K  +D PS P  P 
Sbjct: 6724 NFESTEDTK-LKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVKAKSPFDLPSAPGTPS 6782

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733
            I  +IS  ++T+ W PP  DGG  +  + +E+ E  + RW++++  D    T+ +  L +
Sbjct: 6783 IS-DISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISRFDFTETTFSVTGLKD 6841

Query: 1734 NCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
              +Y FRV A+N +G  +  E + P   K   + PS          I  ES+ + W    
Sbjct: 6842 GNDYEFRVAAKNKIGIGKFSEPTRPTKAKEPYESPSTPDVSN----ITGESMTLNWTAPR 6897

Query: 1793 KNGGSPIIDYKVEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSL 1849
             +GGSPI  Y +E ++ G+  W              +  L     Y+FR+ A N+ G   
Sbjct: 6898 TDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAEYEFRVIAENKAGLGR 6957

Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
            P       T     T P  P    V + T+ ++T+ W+ P  +GGS IT Y IE K+   
Sbjct: 6958 PSQVTHPFTAKPPYTTPGIPDQPEVEDVTATTITISWSPPSYDGGSKITGYTIESKSDAT 7017

Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVRLEKHATVPSP 1968
              W KI +       +    +KE  E  FR++A N  G       S+ V  +     P P
Sbjct: 7018 MRWVKIESTVPDT-TYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVTCKPPYDPPPP 7076

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
            P AP    +  ++  +T W TP  DGG+P+ GY I  +D   T W++  +V   T  F I
Sbjct: 7077 PDAPDVYNITPTSAALT-WSTPRQDGGSPITGYVIDKKDKYSTRWVKADEVPAGTTDFTI 7135

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
            + L   + Y  R+ A N  G+ +P    E F
Sbjct: 7136 KGLQAGNDYEFRVSAVNAAGVGKPSAPCERF 7166



 Score =  194 bits (474), Expect = 2e-47
 Identities = 127/455 (27%), Positives = 212/455 (46%), Gaps = 18/455 (3%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKV-YDKPSKPEGPV 1673
            N T   KT    +  L    S ++ + A N  G      S+ +VT K  Y +P+ P  P 
Sbjct: 6522 NRTQVLKTG-FNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQ 6580

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLN 1732
            I   ++ +S T+ W PP DDGG  +T Y IEK +  + RW +V  D   D + + +  L 
Sbjct: 6581 ISN-VTADSATLTWSPPRDDGGSSITGYFIEKKDKFSPRWTRVNHDAVTDTK-FTVPALV 6638

Query: 1733 ENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
               EY FRV+AQN  G S+  E +E  ++++  + P           +   ++ +TW P 
Sbjct: 6639 PGEEYQFRVVAQNKAGASKPSEPTESTLVRSPFNEPGAPGAPETSN-VTETTLTLTWTPP 6697

Query: 1792 EKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTS 1848
              +GGS I  Y VE K     +W           +++   L+  T Y+FR+ A N+ G S
Sbjct: 6698 FSDGGSRITGYYVEKKDRMSLRWSPVNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRS 6757

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
             P      +        PS P    +S+ +S ++TL+W  PES+GG+ I  +I+E +   
Sbjct: 6758 KPSAPSYPVKAKSPFDLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQF 6817

Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
               W +I     +     +  +K+ ++  FR++A+N +G+     S+  R  K       
Sbjct: 6818 STRWVQISRFDFTETTFSVTGLKDGNDYEFRVAAKNKIGIG--KFSEPTRPTKAKEPYES 6875

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
            P+ P    + G ++ + +W  P  DGG+P+ GY I  R+  ++ W  V +  + +L   +
Sbjct: 6876 PSTPDVSNITGESMTL-NWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVV 6934

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             +L +   Y  R+ A N+ GL  P +   PF   P
Sbjct: 6935 PNLRQGAEYEFRVIAENKAGLGRPSQVTHPFTAKP 6969



 Score =  193 bits (471), Expect = 4e-47
 Identities = 135/453 (29%), Positives = 190/453 (41%), Gaps = 18/453 (3%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTL-----KVYDKPSKPEGPVIMREIS 1679
            K +  ++ +L      ++ + A N AG     EV+L       YD PS P  P      S
Sbjct: 7230 KETTFKVNDLSEDRKYEFRVSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATNVDS 7289

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             E V +EW  P+ DGG  +T Y IE  +    RW K+        T+ +  L  N EY F
Sbjct: 7290 TELV-LEWTAPVADGGSPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQF 7348

Query: 1740 RVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            RVIA+N VG     ++ E IV K   D P             + S  + W P   +GGSP
Sbjct: 7349 RVIAENKVGLGRPSDNTESIVAKPPYDTPDAPESVQVTGTTAS-SASLEWSPPFSDGGSP 7407

Query: 1799 IIDYKVEIK-QEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            +  Y VE K Q   +W              +  L     YQFR+ A N  G      S  
Sbjct: 7408 VTGYFVERKDQYSARWTRVNRVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTK 7467

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
               I   +  PS P    ++  T+ S TL W  P  +GGS +T YI+E K      WT I
Sbjct: 7468 PTVIKDPVDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPI 7527

Query: 1916 VTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPL 1973
                 +   +C I  +KE +E  FR+ A N  G S P+     ++ K    VP  P+ P 
Sbjct: 7528 ERCTDT---NCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPSKP- 7583

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033
            ++  V +  V   W  P  DGG+P+ GY +  ++     W  V    V    F +  L++
Sbjct: 7584 QVTEVKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQ 7643

Query: 2034 NHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
               Y  R+ A N+ G  +P E      V P  G
Sbjct: 7644 KSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYG 7676



 Score =  190 bits (462), Expect = 5e-46
 Identities = 133/464 (28%), Positives = 207/464 (44%), Gaps = 20/464 (4%)

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV- 1662
            K   +  N  E+ +TT      + +  LK  +  ++ + A N AG    +  + VT K  
Sbjct: 4924 KFSTRWTNVSEHMVTTLS----LNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFP 4979

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
            ++ P  P  P I R IS  SV + W PP  DGG ++T Y IEK +  + RW  V     D
Sbjct: 4980 FNAPEAPSPPSIER-ISPTSVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIID 5038

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
               + I+ L E  E  FRV+A N  G  +  ++    +  AL  P           +   
Sbjct: 5039 DTNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQT---TVLAAL--PPGPPESPSISDVKQT 5093

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYA 1841
            SV ++W P E +GGS II Y VE K  G+  K           +   L   + Y+FR+ A
Sbjct: 5094 SVTLSWTPPESDGGSKIIGYIVEKKDMGRWVKVNRSPVRETTMVVTDLVEKSEYEFRVMA 5153

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             N++G   P     ++        P +P    V++     +T+KW+ P S+GGS IT YI
Sbjct: 5154 ENKVGVGEPSAPSSRVVAKLPFDVPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYI 5213

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLE 1960
            +E K      W+++        +  +  + E  +  FRI AEN  G S P+E S++   +
Sbjct: 5214 VEMKEPYSSRWSQVTKTTDFTFK--VTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFTAK 5271

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
                VP  P  P E+  +    +   W  P  DGG+P+LGY +  +D   T W  V    
Sbjct: 5272 LPFGVPGAPDTP-ELTDIKDFSLTVKWLAPTSDGGSPILGYFVEQKDQFSTRWQRVKSSP 5330

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064
            +  LKF + ++ ++      + A N+ G  +P  S      +PG
Sbjct: 5331 ILDLKFTVTNVQDDAECEFHVIAINKAGEGKPSPSVSLTFRLPG 5374



 Score =  186 bits (452), Expect = 8e-45
 Identities = 132/444 (29%), Positives = 201/444 (45%), Gaps = 17/444 (3%)

Query: 1632 IKELKRSHSSKYTIEASNTAGT-----SSVEVTLKV-YDKPSKPEGPVIMREISRESVTI 1685
            + +LK   + ++ + A N AG      SSV VTLK  +  P  P  P  + E+   S+T+
Sbjct: 6130 VPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAV-EVDAVSITV 6188

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
             W  P +DGG  +T Y +E  E  ++ W +V+  +    TY +  L EN    FRVIA N
Sbjct: 6189 RWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVN 6248

Query: 1746 PVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
              G  +      P   K    VPS          +   S+ +TW  S  +GGSPI  Y +
Sbjct: 6249 KAGEGKPSSVGGPFTTKATYTVPSAPGAPDVSN-VKATSMTVTWTKSISDGGSPITGYVL 6307

Query: 1805 E-IKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            E       +W              + +L   + Y FR+ A N  G S P +   K  I K
Sbjct: 6308 EKCDVSTGRWVPVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKP-SEPSKAYIAK 6366

Query: 1862 T-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
                 P  P    ++   ++ +TL W+ P S+GGSPI  Y IE K      WT+      
Sbjct: 6367 PPYGLPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRETI 6426

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVG 1979
               ++ +  + E  E+ FR++AEN  GV   +E+    + K    VPS P  P    + G
Sbjct: 6427 HDMQYTLRELTEGGEVEFRVAAENKAGVGPFSETTGTVIAKSPFDVPSAPGTPKISDITG 6486

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
            +++V+T W  P  DGG  +  + I +RD     W  V +  V    FN+ +LSE  +Y  
Sbjct: 6487 TSLVLT-WTPPSSDGGTEITNFIIELRD-RYGRWTRVNRTQVLKTGFNVMNLSEGDSYEF 6544

Query: 2040 RIYARNEIGLSEPLESDEPFKVIP 2063
            R+ A N++G+ +P +S +     P
Sbjct: 6545 RVTAENKMGVGKPSDSTQKVTAKP 6568



 Score =  184 bits (448), Expect = 2e-44
 Identities = 139/464 (29%), Positives = 204/464 (43%), Gaps = 26/464 (5%)

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV------YDKPSKPEGPVIMR 1676
            T   T  I +K+LK  +  ++ + A N AG  S     K       YD P  P  P    
Sbjct: 2876 TPGDTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKPFVAKPPYDVPDAPGKPA-PS 2934

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
            ++S  SVT+ W PP  DGG  +T Y +E  +  + RW K         T  +  L E  E
Sbjct: 2935 DLSPTSVTLTWTPPPSDGGSPITGYTVEMKDKFSTRWTKATRELISETTVVLPDLKEKEE 2994

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y FRVIA+N  G S+      +  K   + P               S  + W P + +GG
Sbjct: 2995 YQFRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRE-SPTSATVKWSPPKSDGG 3053

Query: 1797 SPIIDYKVEIKQE-GKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
            S I  Y +E K++   +W          +  ++ L      +FR+ A N+ GT  P    
Sbjct: 3054 SEITGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKP---S 3110

Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
               T+  +  PP  P    VS+    S T+ WT P  +GGS IT Y IE +      WT+
Sbjct: 3111 QVATL--SAKPPGAPDAPEVSDIDRTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTR 3168

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            +           + ++ EK++  FR+ AEN VG   P+ + S R    A     P AP  
Sbjct: 3169 VNKSLVKDTTLKVNDLTEKNQYEFRVIAENKVGPGEPS-NPSARFTAKAPF-DEPEAPYS 3226

Query: 1975 IRMVGSNIVMT----SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
              +  S+I  T    SW  P+ DGG+P+LGY +  +D   + W +V K  +    F + +
Sbjct: 3227 --LAASDITPTSATLSWLPPDSDGGSPILGYTLETKDRFSSRWTKVNKGLLQETSFKVTN 3284

Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074
            L EN+ Y+ R+ A N+ G S+P  S+E  K I        E PG
Sbjct: 3285 LEENNEYVYRVIAENKAGPSKP--SNE-CKFIAKHQFETPEAPG 3325



 Score =  181 bits (440), Expect = 2e-43
 Identities = 197/875 (22%), Positives = 344/875 (39%), Gaps = 68/875 (7%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            V W K  S ++ + +  + +  +   + I+ C  +D+  +    LD  +T     + +  
Sbjct: 7907 VKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFK---LDVSNTAGS--DAITI 7961

Query: 1287 PPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPND-------EWIVNSKIIKKCKHTKPSI 1338
              +++D   + R      D+     + ++ +P D        +I+  +   +   T+ + 
Sbjct: 7962 RVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTT 8021

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEI 1392
             +   ++ +  ++   + ++++   N  G ++ +E   TI      D P  P KP +  +
Sbjct: 8022 RALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDVPEAPSKPLVTNV 8081

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450
             S S+ + W  P++ G + I  Y++E +E  +  W  V  ++   TS  I  L     Y 
Sbjct: 8082 TSDSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRIPRLMRGEEYE 8141

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            FR  A N      AS  +   +  ++T +      +  + I  +  E   +   + G+P 
Sbjct: 8142 FRVSAENRAGPGPASTPSAPIRA-EDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPT 8200

Query: 1511 PKVTWYRDGKKLKTA---KATYENRXXX-XXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            P VTW  DG+ LK +   +    NR                Y     N  G       V 
Sbjct: 8201 PAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGGRYTINLKNTAGAESLDVEVR 8260

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNI 1621
            +  +P          +   V +    T  +   PP +     +  Y    + E + ++  
Sbjct: 8261 VFDRPG---PPRGPLEMSNVSES---TVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKH 8314

Query: 1622 TTKEKTSVIRIK--ELKRSHSSKYTIEASNTAGTS----SVEVTLK-VYDKPSKPEGPVI 1674
              K+    +  K   LK +   ++ + A N  G S       +T +  Y+ P  P  P +
Sbjct: 8315 VNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITPQGQYNVPDPPSAPKV 8374

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
               I  +SVT+ W PP +DGG  +T Y +E  +  + RWIK         T+   +L   
Sbjct: 8375 TNIIG-DSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLTPTPDMTFRASRLIRG 8433

Query: 1735 CEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
             EY FRV A N  G     E S  ++++     P           I   + +   F  + 
Sbjct: 8434 TEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFEKVITIRAGHT--FRID- 8490

Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPY 1851
                  I YK         W           RI   S N  TT   R   R + G  +  
Sbjct: 8491 ------IPYKA-TPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIR 8543

Query: 1852 TS----DDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
             S    +D +T+    +  PS P+    + +  S  VTL W+ P  +GGSPIT Y++E +
Sbjct: 8544 ASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEKR 8603

Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965
                 SWT + +         +  + E  E  FR+ AEN +GVS P ES+ +  +    V
Sbjct: 8604 EGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDYDV 8662

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD--VTKTMWMEVGKVDVNT 2023
            P  P   +++  + S+ V  +W  P+ DGGAP+ GY +  R+    +  W       V  
Sbjct: 8663 PDQP-GKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPVMD 8721

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                +  LSE   Y  R+ A N+ G+S P  +  P
Sbjct: 8722 TTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAP 8756



 Score =  180 bits (438), Expect = 4e-43
 Identities = 162/702 (23%), Positives = 276/702 (39%), Gaps = 37/702 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
            P PP  P +  I   S+ + W  P N G + +  YVVE ++  +  WI    +T T    
Sbjct: 8366 PDPPSAPKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKA-TLTPTPDMT 8424

Query: 1441 ---QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
                 L   + Y FR  AVN        E +    V+ E     P         K IT  
Sbjct: 8425 FRASRLIRGTEYEFRVCAVNRAGTGRPGEPSN--TVMVEDPAVKPKFNLDARFEKVITIR 8482

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENR---XXXXXXXXXXXXXXXYKC 1550
                  +   +   P P V+W ++G  + K+ + T ++                   Y  
Sbjct: 8483 AGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVI 8542

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608
             A N  GE   +  V +   P        + +   ++V   W       G P    +  K
Sbjct: 8543 RASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEK 8602

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----Y 1663
                  +    N+++K   +  R+ +L      ++ + A N  G S    + ++     Y
Sbjct: 8603 REGGYGSWT--NVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDY 8660

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WIKVADVDR 1721
            D P +P G + +  I  +SV++ W  P  DGG  +T Y +EK E       W + +    
Sbjct: 8661 DVPDQP-GKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPV 8719

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780
               T  + +L+E  EY FRV A N  G S  A  + P++++     P           I 
Sbjct: 8720 MDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVIT 8779

Query: 1781 NESVYITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
              +  +       +G  +P + + ++ KQ  +G++ K            +      +  +
Sbjct: 8780 VRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTY 8839

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSP 1896
             I   N+ GT    T+  ++ +   L  PS P   + V+  T  SVTL W  P+ +GG+ 
Sbjct: 8840 TIKISNKAGTD---TATIRVAV---LDKPSAPEGPIKVTSITCDSVTLAWEPPKDDGGAD 8893

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            IT YI+E +      WT++ +   S   + +  +K+    +FR+ A +  G S P E++ 
Sbjct: 8894 ITGYILERREPDQFRWTRVTSTLSSPR-YAVTGLKDGRSYLFRVRAVSKYGESEPLETED 8952

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
              L K A    P     +   V  + +  SW  P  DGGA +  Y + I++   T W+  
Sbjct: 8953 AILIKSAFEKPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKETRGTRWLRA 9012

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             +  + +  F +  LS+   Y  R+ A NE GL    ++  P
Sbjct: 9013 TRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSAP 9054



 Score =  178 bits (434), Expect = 1e-42
 Identities = 179/700 (25%), Positives = 273/700 (39%), Gaps = 52/700 (7%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            +D PS P +P I  I + S  + W  P   G S +  Y+VE ++  T  W  ++  T T 
Sbjct: 7475 VDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPIERCTDTN 7534

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
              I  LK  + Y+FR  A N+   S  S  ++  KV K          KP   +T     
Sbjct: 7535 CKISGLKEGNEYQFRVVATNKAGQSAPSNPSQ-PKVAKSPYDVPEAPSKP--QVTEVKAT 7591

Query: 1498 DIELTC----IFGGVPQPKVTWYRDGKKLKTA------KATYENRXXXXXXXXXXXXXXX 1547
             + L        GG P   +T Y   KK + A        T                   
Sbjct: 7592 SVTLKWRPPGSDGGSP---ITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQKSEYE 7648

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW- 1606
            ++ +A N  G  + S     +    + +     +    V  ++  T+V     PPE    
Sbjct: 7649 FRVVAANKKGFGQPS-----EPTNSVLVKPPYGRPSPPVVTDFTKTSVTLQWNPPESDGG 7703

Query: 1607 -YKNGNKLENDKEYNITTKEKTSVIRIK------ELKRSHSSKYTIEASNTAGT------ 1653
             +  G  LE  + Y++     TS   +K      +LK     ++ + A N AG       
Sbjct: 7704 SHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDG 7763

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            S +      +  PS P  P I   I+ +SVT+ W PP  DGG  +T Y +E+ +  + RW
Sbjct: 7764 SELATAKSKFGVPSPPGEPTI-SNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTRW 7822

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
            + V           I  L     Y FR++A N  G S+   S    I  A+  P      
Sbjct: 7823 VPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKP-TSPTDSIGMAV-APKLDTYK 7880

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSI 1831
                 +             K    P + +  +    Q   + K           I+    
Sbjct: 7881 YHDTMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVR 7940

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEP 1889
                 F++   N  G+       D ITI  + L  P QPR   V  +  S  + L W EP
Sbjct: 7941 EDEGSFKLDVSNTAGS-------DAITIRVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEP 7993

Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
               GGSPIT+YIIE +     SWT++ T         + +++E    +FR+ A N +G S
Sbjct: 7994 ADTGGSPITHYIIERREEDRTSWTRLTTRALDTTVR-VTSLQEGASYVFRVFAVNKIGDS 8052

Query: 1950 LPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
             P E+ ++++L+K   VP  P+ PL +  V S+ V   W +P+ DGGAP+ GY I  ++ 
Sbjct: 8053 EPLETKETIKLKKKYDVPEAPSKPL-VTNVTSDSVTLEWHSPKSDGGAPISGYIIEKKET 8111

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            +   W +V  V        I  L     Y  R+ A N  G
Sbjct: 8112 SSNYWSKVTTVSSGVTSHRIPRLMRGEEYEFRVSAENRAG 8151



 Score =  165 bits (400), Expect = 2e-38
 Identities = 125/447 (27%), Positives = 195/447 (43%), Gaps = 18/447 (4%)

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKP--SKPEGPVIMREI 1678
            TT    ++  +  L +    ++ + A+N  G     E T  V  KP   +P  PV+  + 
Sbjct: 7628 TTPVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPPVVT-DF 7686

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            ++ SVT++W PP  DGG  +T Y +EK E  + RW            + ++ L E  +Y 
Sbjct: 7687 TKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYE 7746

Query: 1739 FRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
            FRV+A N  G     + SE    K+   VPS          I  +SV + W P   +GGS
Sbjct: 7747 FRVMALNKAGIGPPSDGSELATAKSKFGVPSPPGEPTISN-ITAKSVTLNWTPPSSDGGS 7805

Query: 1798 PIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
            P+  Y VE       +W           +  I  L    +YQFRI A N  GTS P +  
Sbjct: 7806 PVTGYTVERADRFSTRWVPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPT 7865

Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
            D  +IG  + P      +  +       T     P      P   +  +  T++  S  K
Sbjct: 7866 D--SIGMAVAPKLDTYKYHDTMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIK 7923

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            I T         I+N   +DE  F++   NT G    +++ ++R++     P  P  PL 
Sbjct: 7924 IDTTDRDTIV-TIKNCVREDEGSFKLDVSNTAG----SDAITIRVQV-LDRPEQPRGPLV 7977

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
             + +GS  +  SW  P   GG+P+  Y I  R+  +T W  +    ++T    +  L E 
Sbjct: 7978 AKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTTRALDTT-VRVTSLQEG 8036

Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +Y+ R++A N+IG SEPLE+ E  K+
Sbjct: 8037 ASYVFRVFAVNKIGDSEPLETKETIKL 8063



 Score =  163 bits (395), Expect = 6e-38
 Identities = 107/441 (24%), Positives = 193/441 (43%), Gaps = 18/441 (4%)

Query: 1333  HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTIL-----DKPSPPGK 1386
             H +P   S   + T KK+++    + ++  EN  G +  +E+   IL     D PS PG+
Sbjct: 9837  HWQPLGTSLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGR 9896

Query: 1387  PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLK 1444
             P I  I   S+++ W  P + G S+I  Y++E ++  +  WI   +  +T T  ++ NL+
Sbjct: 9897  PTISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTTSQRWIKANHEPVTTTSHTLINLR 9956

Query: 1445  TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTC 1503
              ++ Y FR  A N +  S+ S  ++   V        P  V KP +N      + + +TC
Sbjct: 9957  EDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKP-QNAHVAEGKSVTVTC 10015

Query: 1504  IFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
                G P P+V WYR G+++   +        N                      N  G +
Sbjct: 10016 QVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGTI 10075

Query: 1560  ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKE 1618
               +  + +   P +T+        H +  E+++  V   G P P + W ++G  + +   
Sbjct: 10076 TDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGR 10135

Query: 1619  YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
             + I      + + I+ + +  + KY++ ASN  G  +  + + +   P  P     + EI
Sbjct: 10136 FEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECL-EI 10194

Query: 1679  SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
             + E++ + W PP+ DGG  ++ Y +EK E     W +V        T  +  L  + +Y 
Sbjct: 10195 TSEAIRLAWNPPIYDGGSNISSYMVEKREVGVLTWARVISSKNTHHT--VINLRSDTQYQ 10252

Query: 1739  FRVIAQNPVGFSEALESEPIV 1759
             FRV A N  G SE  E+  ++
Sbjct: 10253 FRVTAFNMYGASEPCEATAVI 10273



 Score =  137 bits (331), Expect = 4e-30
 Identities = 146/650 (22%), Positives = 272/650 (41%), Gaps = 29/650 (4%)

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENS 810
            V L       P  T+   + +K  +  PT+ D    H       +KV+ + +   K E +
Sbjct: 149  VTLEKPTEAAPEETVFTLEPSKVDETAPTEVDFQIAHEKPEEHEEKVEIK-IMKKKPEET 207

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEI-------TVKEKGTIKLVARVTRNPVPS 863
            E + E       +  T+E  E        +++        +++KG I++  +V R  + +
Sbjct: 208  EDVVEVKLTKKKKPLTKEEKEAEEIFELLKDVEPKNYEKVLRKKGIIQM--KVIRKHIEA 265

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCV--ASNSAGKSSHGAR 920
            +  ++  E +   +  TQ  + E    V   V SE+ ++   K V  A   A        
Sbjct: 266  VEKHKAEETVK--QLATQEVEAEVTLRVSEEVPSEVVEAAVIKPVEAAPVEAAPVKAVPE 323

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEG 979
              +  E+  F + L K  +  +G T  L C+ +      +W  + K +   D  E+ ++G
Sbjct: 324  KKLKPEEWKFTEEL-KPAKGFKGDTCELVCEVNDENAIVEWVKHGKVLKPSDKYELKEDG 382

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
                         D     C +   +T   L V+  + + +  L+   + E++ A+L  E
Sbjct: 383  TKRILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPV-KIVGDLKPLTITERETAVLTCE 441

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            +++  A V W +DGE I    +KY+    G  +KL I+N S  D  EY+C L   S T  
Sbjct: 442  VSNTKAAVTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPEDAAEYTCQLPRSSSTMT 501

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            +TV E P E+++ L          ATFE E+++  A V W K   E+  S+  ++  DG+
Sbjct: 502  LTVNEKPLEVLSPLTKLFAYLTGNATFECEVSEPWANVTWLKGDKEVVPSDKYKMESDGR 561

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
             +++ I     DD  +Y+C + + K +A L + E +I  T + PE              E
Sbjct: 562  FRRMIIQGIAEDDVSDYTCVLRDKKTSADLLLRE-TIKIT-KPPEDEDSRERQSVKFVCE 619

Query: 1220 IPDET--LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            +  +    DV W K   V+   ++  +I++    TL+I   +  D  +Y+ ++ + +   
Sbjct: 620  LTGDAAKADVKWKKGGQVVRKDKRHKIINEGLVSTLVIEDLSPSDAGKYSVLVDNMEMPF 679

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKP 1336
             L V+ ++ PP      +    + G           +P P  ++  + K I  +      
Sbjct: 680  TLSVQALK-PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITPENSDVTF 738

Query: 1337 SID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
              D  ++   +   +V   DAG Y +  +N  G  +V+  V+++  P PP
Sbjct: 739  QFDEATQEHKVIFHEVTPKDAGKYLVIAKNESG--EVKQAVSMMVTPRPP 786



 Score =  134 bits (325), Expect = 2e-29
 Identities = 107/428 (25%), Positives = 189/428 (44%), Gaps = 26/428 (6%)

Query: 1632  IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
             +K+ +R  S  YT+EA N  G  S+   + V D+P  P+GP+ ++ I+  S T  W  PL
Sbjct: 9757  VKDAEREDSGTYTLEAVNELGRHSITARVNVLDRPGPPQGPISIQSITNNSATFTWTLPL 9816

Query: 1692  DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             DDGG  + +Y +   E +   W  +      +  +  +KL +N  Y+ RV A+N  G S 
Sbjct: 9817  DDGGAPIQRYQVSIRESNRTHWQPLG--TSLLPNFTAKKLKDNTHYVLRVTAENQYGTSR 9874

Query: 1752  ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-E 1809
              LE  E I++K+  D PS          I  +SV+++W     +GGS I  Y +E +   
Sbjct: 9875  PLEIREAILVKSPFDPPS-APGRPTISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTT 9933

Query: 1810  GKKW-KXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL--TP 1865
              ++W K         +  +  L  +T Y+FR+ A N +G S P T   ++ +   +   P
Sbjct: 9934  SQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVP 9993

Query: 1866  P---SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
             P   S+P+N  V+E  S +VT    +        +  Y +  +   G+ +   +   G++
Sbjct: 9994  PQFVSKPQNAHVAEGKSVTVT---CQVSGYPAPEVRWYRLGREIAHGRKFQ--IGGDGNI 10048

Query: 1923  HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
             H      +  +D     ++  N  G        +V +    T+P+    P+ + ++G  I
Sbjct: 10049 HTLTANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHL-LLGEYI 10107

Query: 1983  VM--TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
             ++     GTP      P + ++    DV      E+ K   +     IR +++       
Sbjct: 10108 MLKVPFSGTPR-----PSIKWDRDGEDVVDGGRFEI-KATPHDTTLIIRGITKEDAGKYS 10161

Query: 2041  IYARNEIG 2048
             + A NE+G
Sbjct: 10162 VVASNELG 10169



 Score =  127 bits (306), Expect = 4e-27
 Identities = 120/471 (25%), Positives = 192/471 (40%), Gaps = 30/471 (6%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P  EV W K+G ++      N   + +   I ++ +    + KY+ E     G  S    
Sbjct: 9090 PNAEVKWMKDGFQIFGYDRVNEIKEGQRRAITLRNVGDRDTGKYSCEC----GKQSTSCW 9145

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
            L V   P+          + +   T+    P    G    K  +E H  D       A +
Sbjct: 9146 LSVTAPPTIDVKAYKDVVVVKTGNTLRLLVPYT--GCPSPK--VEWHRHD-------ARI 9194

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP-----IVIKTALDVPSXXXXX 1773
              D  T+ I+  +   +   R + +   G FS  L +E      I+    +DVP      
Sbjct: 9195 SEDTRTH-IETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAIIRVNVIDVPGPPTGP 9253

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSI 1831
                 +    V ++W P + +GGSPI  Y VE ++  ++ W             +  LS 
Sbjct: 9254 LEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMWTSVSNYVSHVPFTVSGLSE 9313

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
               Y+FR+ A N  G   P    + + I    + P+ P    +S      +TL W+EP  
Sbjct: 9314 KVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEISNVQRDRMTLTWSEPSH 9373

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            +GG PI  YIIE +    K W ++           I+ + E     FRISA N  G+  P
Sbjct: 9374 DGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIKGLTEGSNYEFRISAVNDTGIGNP 9433

Query: 1952 TE-SQSVRLEKH-ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
            +E S   +L +  A  P+PP AP+ I  + +  V  SW  P  DGG+ +  Y +  R   
Sbjct: 9434 SEVSAPPKLARSPAGRPTPPGAPI-IGDITATSVSLSWSAPSTDGGSEITHYIVERRLKG 9492

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEPF 2059
              MW++  +  V+    ++ +L E+  Y  R+ A N  G  S+P  + E F
Sbjct: 9493 SYMWID--RTVVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDPSRASESF 9541



 Score =  109 bits (261), Expect = 1e-21
 Identities = 70/229 (30%), Positives = 106/229 (46%), Gaps = 8/229 (3%)

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
            T +F I   NE G     T+  ++ +     PP+ P    +++     V+L W  P+ +G
Sbjct: 9221 TGKFSITLTNEAGQE---TAIIRVNVIDVPGPPTGPLE--ITDVGRHCVSLSWEPPKDDG 9275

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            GSPI +Y +E +    + WT +      V    +  + EK E  FR+ AEN  GV  P  
Sbjct: 9276 GSPIQSYTVEQREANRRMWTSVSNYVSHV-PFTVSGLSEKVEYEFRVCAENINGVGPPLH 9334

Query: 1954 S-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
              + V +    +VP+PP  P EI  V  + +  +W  P  DGG P+ GY I  R+     
Sbjct: 9335 GIEPVVIVAPYSVPTPPGKP-EISNVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQ 9393

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            W  V +  +    F I+ L+E   Y  RI A N+ G+  P E   P K+
Sbjct: 9394 WNRVNRDLIKDTTFTIKGLTEGSNYEFRISAVNDTGIGNPSEVSAPPKL 9442



 Score =  105 bits (253), Expect = 1e-20
 Identities = 120/527 (22%), Positives = 200/527 (37%), Gaps = 32/527 (6%)

Query: 1343  ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
             A L +K  E  D+G Y L   N  G   +   V +LD+P PP  P +I  I ++S    W
Sbjct: 9753  AELYVKDAEREDSGTYTLEAVNELGRHSITARVNVLDRPGPPQGPISIQSITNNSATFTW 9812

Query: 1402  DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
               P + G + I  Y V  +E + T W  +        + + LK N+ Y  R  A N+   
Sbjct: 9813  TLPLDDGGAPIQRYQVSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHYVLRVTAENQYGT 9872

Query: 1462  SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----R 1517
             S   E  E   V       S      + NI  + +  +  T          +T Y    R
Sbjct: 9873  SRPLEIREAILVKSPFDPPSAPGRPTISNIQRD-SVHVSWTAP-SSDGGSSITGYIIERR 9930

Query: 1518  DGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVG--IQQKPVI 1573
             D    +  KA +E                 Y  + +A N  G  E S V    + + P+ 
Sbjct: 9931  DTTSQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPID 9990

Query: 1574  TISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             T+  + + +        G    VT  + G P PEV WY+ G ++ + +++ I        
Sbjct: 9991  TVPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHT 10050

Query: 1630  IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDK---PSKPEGPVIMREISRESVT 1684
             +   +L      + ++  +N  G  T + E+ + V  K   P++   P+ +  +  E + 
Sbjct: 10051 LTANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHL--LLGEYIM 10108

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
             +  K P         K+  +  +  +    ++     D  T  I+ + +     + V+A 
Sbjct: 10109 L--KVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT-TLIIRGITKEDAGKYSVVAS 10165

Query: 1745  NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
             N +G      S  + I    D P           I +E++ + W P   +GGS I  Y V
Sbjct: 10166 NELGHDTC--SIQVNILRHPDSP----RNLECLEITSEAIRLAWNPPIYDGGSNISSYMV 10219

Query: 1805  EIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
             E ++ G   W            +  L  +T YQFR+ A N  G S P
Sbjct: 10220 EKREVGVLTWARVISSKNTHHTVINLRSDTQYQFRVTAFNMYGASEP 10266



 Score =  103 bits (248), Expect = 4e-20
 Identities = 74/283 (26%), Positives = 122/283 (43%), Gaps = 8/283 (2%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
            +P+PPG P I +I ++S+++ W  P   G S I +Y+VE +   +  WI    +  T  S
Sbjct: 9449 RPTPPGAPIIGDITATSVSLSWSAPSTDGGSEITHYIVERRLKGSYMWIDRTVVHDTSCS 9508

Query: 1440 IQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            + NL  +  Y FR  AVN   + SD S  +E +    +    +P++   ++N      + 
Sbjct: 9509 VNNLVEDKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQT 9568

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR-XXXXXXXXXXXXXXXYKCIAFN 1554
                C   G P+PKV+W   G++L   +    T +N                 Y  IA N
Sbjct: 9569 GMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKN 9628

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKL 1613
             HG V +S  + IQ+ P ++I         + G E  +   +  G P P   W ++  + 
Sbjct: 9629 KHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGE- 9687

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            E D     +TKE+  V    EL     ++Y +    T  T  +
Sbjct: 9688 ELDTRGRYSTKEQGRVHDF-ELPDLGGNRYPLSGFYTLKTEKL 9729



 Score =  103 bits (246), Expect = 7e-20
 Identities = 125/592 (21%), Positives = 231/592 (39%), Gaps = 39/592 (6%)

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
            T +EL  E +  L++     G   T E  ++  +A V+W KDG +I   + +    +G++
Sbjct: 9059 TPIELA-EFVEPLKDVSAKAGKIVTLECRISNPNAEVKWMKDGFQIFGYDRVNEIKEGQR 9117

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVE 1219
            + + + +    D G+YSCE G    +  L+V   P+I+        ++   NT   L   
Sbjct: 9118 RAITLRNVGDRDTGKYSCECGKQSTSCWLSVTAPPTIDVKAYKDVVVVKTGNTLRLLVPY 9177

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT 1277
                +  V W++  + I +  +  + +   +  + IR     D  +++  L +   + T 
Sbjct: 9178 TGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETA 9237

Query: 1278 KLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             ++V V++ P P     E     +    ++          P   + V  +   +   T  
Sbjct: 9238 IIRVNVIDVPGPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMWTSV 9297

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCG-----HA-DVEMNVTILDKPSPPGKPNIL 1390
            S        T+  +       +++  EN  G     H  +  + V     P+PPGKP I 
Sbjct: 9298 SNYVSHVPFTVSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEIS 9357

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSS 1448
             +    + + W EP + G   I  Y++E +E  + +W  V    I  T  +I+ L   S+
Sbjct: 9358 NVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIKGLTEGSN 9417

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--IFG 1506
            Y FR  AVN+  I + SE +   K+ +    +      P+    T  +  +  +     G
Sbjct: 9418 YEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATSVSLSWSAPSTDG 9477

Query: 1507 GVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE---- 1558
            G    ++T Y   ++LK +      T  +                ++  A N  G     
Sbjct: 9478 G---SEITHYIVERRLKGSYMWIDRTVVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDP 9534

Query: 1559 -------VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
                   V  S + G     +I I N  + +    G   +    I G P P+V W  +G 
Sbjct: 9535 SRASESFVAESQLPGAAPSILIEIQNAMVAE----GQTGMFMCKISGSPKPKVSWMHHGR 9590

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLK 1661
            +L   +++NIT       I +  +    +  YTI A N  G+  SS E+ ++
Sbjct: 9591 ELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQ 9642



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 9/217 (4%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            + + A NE+G    ++   ++ +     PP  P +  +   T+ S T  WT P  +GG+P
Sbjct: 9768 YTLEAVNELGR---HSITARVNVLDRPGPPQGPIS--IQSITNNSATFTWTLPLDDGGAP 9822

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            I  Y +  +      W  + T    +     + +K+    + R++AEN  G S P E + 
Sbjct: 9823 IQRYQVSIRESNRTHWQPLGT--SLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIRE 9880

Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
              L K     PS P  P  I  +  + V  SW  P  DGG+ + GY I  RD T   W++
Sbjct: 9881 AILVKSPFDPPSAPGRPT-ISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTTSQRWIK 9939

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                 V T    + +L E+  Y  R+ A N +G SEP
Sbjct: 9940 ANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEP 9976



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 105/439 (23%), Positives = 182/439 (41%), Gaps = 37/439 (8%)

Query: 1633  KELKRSHSSKYTIEASNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIE 1686
             K+LK +      + A N  GTS  +E+   +     +D PS P  P I   I R+SV + 
Sbjct: 9852  KKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTISN-IQRDSVHVS 9910

Query: 1687  WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
             W  P  DGG  +T Y IE+ +  + RWIK         ++ +  L E+ EY FRV+A+N 
Sbjct: 9911  WTAPSSDGGSSITGYIIERRDTTSQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENS 9970

Query: 1747  VGFSE-ALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
             +G SE +  S+ ++++  +D   P            + +SV +T   S    G P  + +
Sbjct: 9971  MGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVS----GYPAPEVR 10026

Query: 1804  -VEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
                + +E   G+K++             +L      +  +   N+ GT +    +  + +
Sbjct: 10027 WYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGT-ITDAFELNVLV 10085

Query: 1860  GKTLTPPSQ---PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
                LT P++   P + ++ E     V    T   S         +++    + K+     
Sbjct: 10086 MPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT 10145

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
             T+        I  I ++D   + + A N +G    T S  V + +H   P  P   LE  
Sbjct: 10146 TL-------IIRGITKEDAGKYSVVASNELGHD--TCSIQVNILRH---PDSPRN-LECL 10192

Query: 1977  MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
              + S  +  +W  P +DGG+ +  Y +  R+V    W  V  +        + +L  +  
Sbjct: 10193 EITSEAIRLAWNPPIYDGGSNISSYMVEKREVGVLTWARV--ISSKNTHHTVINLRSDTQ 10250

Query: 2037  YMIRIYARNEIGLSEPLES 2055
             Y  R+ A N  G SEP E+
Sbjct: 10251 YQFRVTAFNMYGASEPCEA 10269



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 68/264 (25%), Positives = 109/264 (41%), Gaps = 5/264 (1%)

Query: 1226  DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
             +V WY+    I    KF +  D    TL   +   +D  E +  + +   T     E+ V
Sbjct: 10024 EVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGTITDAFELNV 10083

Query: 1285  EFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
                PK+    R      +  G  + L V +   P+P+ +W  + + +      +      
Sbjct: 10084 LVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPH 10143

Query: 1342  SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
               +L I+ +   DAG Y +   N  GH    + V IL  P  P     LEI S +I + W
Sbjct: 10144 DTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECLEITSEAIRLAW 10203

Query: 1402  DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
             + P   G S I  Y+VE +E+    W  V +   T  ++ NL++++ Y+FR  A N    
Sbjct: 10204 NPPIYDGGSNISSYMVEKREVGVLTWARVISSKNTHHTVINLRSDTQYQFRVTAFNMYGA 10263

Query: 1462  SDASETTEYYKVIKETKIQSPTVE 1485
             S+  E T      K +K   P  E
Sbjct: 10264 SEPCEATAVI-CTKSSKAGRPQFE 10286



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 83/356 (23%), Positives = 147/356 (41%), Gaps = 34/356 (9%)

Query: 496   PVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
             P+ E+    + +  AP F++ L      +G+  +FEC+V     P ITWFR    +  S 
Sbjct: 10632 PLMERECYMDVRDAAPKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISI 10691

Query: 555   DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----APLSDHGSE 610
              ++M YDD    TL++++   +D   +TC A N+ G A+S+  L V+      L   G  
Sbjct: 10692 KYKMLYDDHKY-TLIVQDSEFDDIDEYTCKAVNSYGHATSSASLDVQLLDAKELDSRGER 10750

Query: 611   MTVXXXXXXXXXXXXADIL---EGIPPTFSKKPK----AQYVDEGSDILLE-----CRLV 658
               +            A  L   +   P+  K P+     +  + G   ++        + 
Sbjct: 10751 RGLDMKRKKIPLGERAKKLRKAQAEAPSSDKAPQLIRPLEDQECGFSFIMPLSFQVAEIP 10810

Query: 659   AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
              +PEP + W  +   + P  +     E  +H     L+I    +  +G YT    N+ G 
Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVH----TLEIDGTTEKDKGQYTAEISNQYGS 10866

Query: 719   ASLPIVLKI------KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
              +    L +      K  +   P     L+ + + +G +  L  +V G P P I W K++
Sbjct: 10867 IATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDH 10926

Query: 773   KPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             K +      ++    D +T S+ I++   ++D G YT  A N  G     + + VE
Sbjct: 10927 KEIFDGQHYSIEFGEDDETCSL-IIQEAFLQDAGTYTCLASNLLGRISCDSYVRVE 10981



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 142/656 (21%), Positives = 259/656 (39%), Gaps = 69/656 (10%)

Query: 503   SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
             S+    AP  + +++     +G T  F C++ G P+P+++W      + P +   +  +D
Sbjct: 9545  SQLPGAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRELMPGRKHNIT-ED 9603

Query: 563   DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXX 621
             + V  +V+  V   + G +T +AKN  G   S+ EL I   P       +          
Sbjct: 9604  NGVFKIVVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQE 9663

Query: 622   XXXXADILEGIP-PTFS-KKPKAQYVDEGSDILL--ECRLVAIPEPDIA---------WL 668
                   +  G P PTF+ ++   + +D         + R+     PD+          + 
Sbjct: 9664  IHIPVTLTYGTPKPTFTWRRHDGEELDTRGRYSTKEQGRVHDFELPDLGGNRYPLSGFYT 9723

Query: 669   FKGEEIVPDENISVAIESDMHMYCSV-----LKITNVKKFQEGTYTVVAVNREGEASLPI 723
              K E+++ +        ++  +   V     L + + ++   GTYT+ AVN  G  S+  
Sbjct: 9724  LKTEKLLRESGCGTTWANNNLLVNVVGGIAELYVKDAEREDSGTYTLEAVNELGRHSITA 9783

Query: 724   VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
              + +      PPQ    ++S I     +   +  +     P   +  + +       +  
Sbjct: 9784  RVNV-LDRPGPPQGPISIQS-ITNNSATFTWTLPLDDGGAPIQRYQVSIRESNRTHWQPL 9841

Query: 784   GDTHSITILKPKKVKDEGVYTLK--AENSEGIA---ETSAVITVEEPTEENAEPPL-FIN 837
             G T  +     KK+KD   Y L+  AEN  G +   E    I V+ P +  + P    I+
Sbjct: 9842  G-TSLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTIS 9900

Query: 838   RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
               Q  +V    T       + +   SIT Y    II   +T +Q +   N E V T   +
Sbjct: 9901  NIQRDSVHVSWTAP-----SSDGGSSITGY----IIERRDTTSQRWIKANHEPVTTTSHT 9951

Query: 898   EID-----SGDYKCVASNSAGKSSHGA-------RVTIDVEKVTFVKHLQKSYETEEGKT 945
              I+       +++ +A NS G S           R  ID     FV   Q ++   EGK+
Sbjct: 9952  LINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAH-VAEGKS 10010

Query: 946   VILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             V + CQ S       +WY   +EI+     +I  +G             DVG I   V +
Sbjct: 10011 VTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTN 10070

Query: 1004  Q--------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGE 1054
             +        E + +++ K T+P  +R      +   +  +L+V  + +    + W+RDGE
Sbjct: 10071 KGGTITDAFELNVLVMPKLTLPARLRT--PIHLLLGEYIMLKVPFSGTPRPSIKWDRDGE 10128

Query: 1055  IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP 1106
              +     +++ +   H   L IR  +  D G+YS +  +E    +C+ +V ++  P
Sbjct: 10129 DVVDG-GRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHP 10183



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 47/136 (34%), Positives = 66/136 (48%), Gaps = 6/136 (4%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I N+   D   F I+  N  G     E+  +R+     VP PPT PLEI  VG + V  S
Sbjct: 9213 IRNVVRGDTGKFSITLTNEAG----QETAIIRVNV-IDVPGPPTGPLEITDVGRHCVSLS 9267

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ DGG+P+  Y +  R+  + MW  V    V+ + F +  LSE   Y  R+ A N 
Sbjct: 9268 WEPPKDDGGSPIQSYTVEQREANRRMWTSVSNY-VSHVPFTVSGLSEKVEYEFRVCAENI 9326

Query: 2047 IGLSEPLESDEPFKVI 2062
             G+  PL   EP  ++
Sbjct: 9327 NGVGPPLHGIEPVVIV 9342



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 109/528 (20%), Positives = 203/528 (38%), Gaps = 37/528 (7%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEAS-----LPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            + +++  + + +E  + V AVN+ G ++      P++++  +   +     +    + VR
Sbjct: 8722 TTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVITVR 8781

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITIL-KPKKVKDEGVYTL 805
             G    L   + G P PT+ W  + K V      K+   T+S  +  K  +  D G YT+
Sbjct: 8782 AGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTYTI 8841

Query: 806  KAENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITV-----KEKGTIKLVARVTRN 859
            K  N  G    T  V  +++P+       +       +T+     K+ G   +   +   
Sbjct: 8842 KISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDSVTLAWEPPKDDGGADITGYILER 8901

Query: 860  PVPS-ITWYR-NNEIISPSETITQNFDGEN----IELVITNVDSE-IDSGDYKCVASNSA 912
              P    W R  + + SP   +T   DG +    +  V    +SE +++ D   + S   
Sbjct: 8902 REPDQFRWTRVTSTLSSPRYAVTGLKDGRSYLFRVRAVSKYGESEPLETEDAILIKSAFE 8961

Query: 913  GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH-NKKEISGMD 971
               + G     +V   +     Q  +     +      +   T  T+W    +K++   +
Sbjct: 8962 KPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKETRGTRWLRATRKQLKSPN 9021

Query: 972  HREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQDFEV 1028
             R   + +GR             +G         +TS  +V K  I   EF+  L+D   
Sbjct: 9022 FRVTGLSKGREYEFRVAAENEAGLGAFS------KTSAPIVSKTPIELAEFVEPLKDVSA 9075

Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            K   +  LE  I++  A+V W +DG  I    ++ +  K G  R + +RN    D G+YS
Sbjct: 9076 KAGKIVTLECRISNPNAEVKWMKDGFQIF-GYDRVNEIKEGQRRAITLRNVGDRDTGKYS 9134

Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQ--KVNKGNKATFEIELTK-GDALVRWFKDGSE 1145
            C    +S +  ++V   PP I  +       V  GN     +  T      V W +  + 
Sbjct: 9135 CECGKQSTSCWLSVT-APPTIDVKAYKDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDAR 9193

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTV 1191
            I       +     + ++ I +    D G++S  + N   + TAI+ V
Sbjct: 9194 ISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAIIRV 9241



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 7/179 (3%)

Query: 1321 WIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +I+  K+ K    T+ + D+    S T++ +   +   +++   N  G       V I  
Sbjct: 4721 YIIEKKV-KGEPWTQVTTDTVDGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVVIAF 4779

Query: 1380 KP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436
            KP  PPG P + ++D +S+ + W  P+  G S +I Y+VE +E     W+ +    + + 
Sbjct: 4780 KPPGPPGTPEVSDVDKTSVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREV 4839

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
              SI +L   + Y FR  A N+V   + S  +E  +++ +   + P+  K LK     P
Sbjct: 4840 TMSITDLVEKNEYEFRVIAENKVGPGEPSSPSE--RIVAKAPYEVPSPPKSLKATDLTP 4896



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 53/228 (23%), Positives = 102/228 (44%), Gaps = 16/228 (7%)

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
            +++ T ++++  E++  ++  V  +     K K      PP++         KR S  ++
Sbjct: 3375 IEETTFLVKRLKENENYQFRVVAHNLAGPGKPKAPKPPTPPEV---------KRLSPTSV 3425

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKH---TKPSIDS-KSASLTIKKVENTDAGIYKLRLE 1363
             +++ A        +    + KK K    T  + DS +  S T+K ++  +   +++   
Sbjct: 3426 QLNWSAPTSDGGSEVTAYIVEKKDKSGRWTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAV 3485

Query: 1364 NNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
            N  G     E+ V     PS P KP + +I  +S  + W  P+N G S +  Y VE +E 
Sbjct: 3486 NKAGTGKPSEVTVIAAKPPSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREK 3545

Query: 1423 DTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
               +W+ V  K +T+T   + +L   ++Y FR  A N     +AS+ +
Sbjct: 3546 GRDQWVRVNRKPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDAS 3593



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 15/202 (7%)

Query: 735   PQVIEPLKSMIVRQGESVILSAQVV---GNPRPTITWCKNNKPVKALPT----KSDGDTH 787
             PQ+I PL+         + LS QV    G P P + W   ++P+K        + DG  H
Sbjct: 10783 PQLIRPLEDQECGFSFIMPLSFQVAEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDG-VH 10841

Query: 788   SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE---PTEENAEPPLFINRFQEITV 844
             ++ I    + KD+G YT +  N  G   T   + V E      ++   P F    ++I +
Sbjct: 10842 TLEIDGTTE-KDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFI 10900

Query: 845   KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSG 902
              E    +L  +VT  P P+I W+++++ I   +  +  F  D E   L+I     + D+G
Sbjct: 10901 VEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQ-DAG 10959

Query: 903   DYKCVASNSAGKSSHGARVTID 924
              Y C+ASN  G+ S  + V ++
Sbjct: 10960 TYTCLASNLLGRISCDSYVRVE 10981



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 39/133 (29%), Positives = 68/133 (51%), Gaps = 8/133 (6%)

Query: 1836  QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             ++ + A NE+G     T   ++ I   L  P  PRN    E TS ++ L W  P  +GGS
Sbjct: 10159 KYSVVASNELGHD---TCSIQVNI---LRHPDSPRNLECLEITSEAIRLAWNPPIYDGGS 10212

Query: 1896  PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
              I++Y++E + V   +W ++++   + H H + N++   +  FR++A N  G S P E+ 
Sbjct: 10213 NISSYMVEKREVGVLTWARVIS-SKNTH-HTVINLRSDTQYQFRVTAFNMYGASEPCEAT 10270

Query: 1956  SVRLEKHATVPSP 1968
             +V   K +    P
Sbjct: 10271 AVICTKSSKAGRP 10283



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 7/135 (5%)

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILEI 1392
            TK  ID    + TIK ++  +   +++   N  G         +    P PP  P+I ++
Sbjct: 5033 TKDIIDD--TNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQTTVLAALPPGPPESPSISDV 5090

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450
              +S+ + W  PE+ G S II Y+VE +  D   W+ V    + +T   + +L   S Y 
Sbjct: 5091 KQTSVTLSWTPPESDGGSKIIGYIVEKK--DMGRWVKVNRSPVRETTMVVTDLVEKSEYE 5148

Query: 1451 FRAYAVNEVDISDAS 1465
            FR  A N+V + + S
Sbjct: 5149 FRVMAENKVGVGEPS 5163



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 44/155 (28%), Positives = 67/155 (43%), Gaps = 11/155 (7%)

Query: 1349 KVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINI 1399
            KV N   G    +++R EN  G  + ++    I+     D P  P KP    +  +S+ +
Sbjct: 5828 KVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPEKPEPSSLTETSVTL 5887

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVN 1457
             W  P + G S I  Y+VE +E   T W++     I KT  ++ +L+  S Y FR  A N
Sbjct: 5888 TWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEYTFRVIAEN 5947

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
            +   S  SE    +K  K   +          NIT
Sbjct: 5948 KAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASNIT 5982



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 8/123 (6%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADV-EMNVTILDKPS-----PPGKPNILEIDSSSI 1397
            + T+ K++  DA  +++   N  G     + +VT+  KP       P +P  +E+D+ SI
Sbjct: 6127 TFTVPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVEVDAVSI 6186

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
             + W  P+N G S I  Y++E +E  ++ W  +S K  ++    +  LK N +  FR  A
Sbjct: 6187 TVRWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIA 6246

Query: 1456 VNE 1458
            VN+
Sbjct: 6247 VNK 6249



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 48/200 (24%), Positives = 85/200 (42%), Gaps = 23/200 (11%)

Query: 532   QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
             ++ G P P++ W+ +   +KP   +  +Y++D V TL I     +D G +T    N  G 
Sbjct: 10808 EIPGMPEPKVKWYHEDRPLKPGAHYH-FYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGS 10866

Query: 592   ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
              ++   L V        +E+ +                    P F    +  ++ EGS  
Sbjct: 10867 IATKCRLDV--------NELFLTKFKDYRK------------PHFDLHLRDIFIVEGSAA 10906

Query: 652   LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
              L+C++  +PEP+I W    +EI   ++ S+    D    CS++ I        GTYT +
Sbjct: 10907 RLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDET-CSLI-IQEAFLQDAGTYTCL 10964

Query: 712   AVNREGEASLPIVLKIKTGE 731
             A N  G  S    ++++  E
Sbjct: 10965 ASNLLGRISCDSYVRVERTE 10984



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 7/120 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKT 1436
            D PS PG P I +I  +S+ + W  P + G + I  +++E ++     W  V    + KT
Sbjct: 6471 DVPSAPGTPKISDITGTSLVLTWTPPSSDGGTEITNFIIELRD-RYGRWTRVNRTQVLKT 6529

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494
              ++ NL    SY FR  A N++ +   S++T+  KV  +     P    E  + N+T +
Sbjct: 6530 GFNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQ--KVTAKPPYSQPAAPNEPQISNVTAD 6587



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 4/134 (2%)

Query: 1336 PSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEID 1393
            P I+S++  S T+K + + +   +++   N  G        T+  KP   P  P + +ID
Sbjct: 3073 PVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQVATLSAKPPGAPDAPEVSDID 3132

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITK-TQTSIQNLKTNSSYRF 1451
             +S  + W  P   G STI  Y +E +E     W  V K++ K T   + +L   + Y F
Sbjct: 3133 RTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQYEF 3192

Query: 1452 RAYAVNEVDISDAS 1465
            R  A N+V   + S
Sbjct: 3193 RVIAENKVGPGEPS 3206



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 27/93 (29%), Positives = 44/93 (47%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            D P  P +P++ +ID + + + W  P + G S I  Y+VE +E  ++ W  V   T    
Sbjct: 5176 DVPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYIVEMKEPYSSRWSQVTKTTDFTF 5235

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
             +  L     Y+FR  A N+   S  SE +  +
Sbjct: 5236 KVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTF 5268



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 17/184 (9%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKE----PPQVIEPLKSMIVRQGES 751
            + N+ + +E T+ V AVN  G  S P    +    E +     P ++  +++ +V +G++
Sbjct: 9509 VNNLVEDKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQT 9568

Query: 752  VILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
             +   ++ G+P+P ++W  + +   P +      D     I +       + G+YT+ A+
Sbjct: 9569 GMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDY-ETGMYTIIAK 9627

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVT-RNPVPSITW 866
            N  G   +SA + ++ P      P L I+R  Q+++V+    I +   +T   P P+ TW
Sbjct: 9628 NKHGSVRSSAELLIQRP------PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTW 9681

Query: 867  YRNN 870
             R++
Sbjct: 9682 RRHD 9685



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 6/139 (4%)

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPPGKPNILEI 1392
            + P +D K    T+  V++     + +   N  G      +V++  + P PPG P +   
Sbjct: 5328 SSPILDLK---FTVTNVQDDAECEFHVIAINKAGEGKPSPSVSLTFRLPGPPGTPEVYNP 5384

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYR 1450
               S+++ W  P   G + II Y +E  E+    W+ +   +I +    + +L  N  ++
Sbjct: 5385 SDKSVDLRWTPPTEQGGTRIIGYFIEKCEVGKDNWVRINRSSIREANYVVGDLTLNCRFK 5444

Query: 1451 FRAYAVNEVDISDASETTE 1469
            FR  A N   +   S+ +E
Sbjct: 5445 FRVCAENRAGVGPPSDYSE 5463



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 9/192 (4%)

Query: 1105  LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
             +PP+ +++ QN  V +G   T   +++   A  VRW++ G EI      Q+  DG    L
Sbjct: 9992  VPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTL 10051

Query: 1164  KIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPAN--TDAYLTVEI 1220
                    +D GE S  V N   T     E    +   L LP  +  P +     Y+ +++
Sbjct: 10052 TANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKV 10111

Query: 1221  P---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
             P        + W +    + D  +F + +     TLIIR  T++D  +Y+ V  +     
Sbjct: 10112 PFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHD 10171

Query: 1276  TTKLKVEVVEFP 1287
             T  ++V ++  P
Sbjct: 10172 TCSIQVNILRHP 10183



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 53/242 (21%), Positives = 97/242 (40%), Gaps = 12/242 (4%)

Query: 803   YTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             + + AENS G +E S V   + V +P +    PP F+++ Q   V E  ++ +  +V+  
Sbjct: 9963  FRVMAENSMGASEPSTVSQRVLVRDPID--TVPPQFVSKPQNAHVAEGKSVTVTCQVSGY 10020

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             P P + WYR    I+         DG NI  +  N     D G+     +N  G  +   
Sbjct: 10021 PAPEVRWYRLGREIAHGRKFQIGGDG-NIHTLTANQLFPEDVGEISVTVTNKGGTITDAF 10079

Query: 920   RVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREII 976
              + + V  K+T    L+       G+ ++L+   S T   S KW  + +++      EI 
Sbjct: 10080 ELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIK 10139

Query: 977   QEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
                             D G    +  ++   +T ++ V     P+  R L+  E+  + +
Sbjct: 10140 ATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECLEITSEAI 10199

Query: 1034  AI 1035
              +
Sbjct: 10200 RL 10201



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 2/118 (1%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            D P  P    +    +SS ++ W  P + G S +  Y VE ++  +  W  V  +  T+T
Sbjct: 7375 DTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVNRVPVTET 7434

Query: 1439 S--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
            +  + +LK    Y+FR  A N   I  +S++T+   +       S  +E  + +IT +
Sbjct: 7435 NMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPVDAPSAPLEPTIASITAD 7492



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 3/94 (3%)

Query: 1091  LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFS 1149
             L +  C  +V   +  P+ I  L+N    +GN   FE E++   + L+ WF+   E+  S
Sbjct: 10633 LMERECYMDVR--DAAPKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIIS 10690

Query: 1150  NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
                ++  D  K  L + D + DD  EY+C+  NS
Sbjct: 10691 IKYKMLYDDHKYTLIVQDSEFDDIDEYTCKAVNS 10724



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATL 568
           P+F  K +   T +G +  F   + GYP P+I + +    I P + D    +D+      
Sbjct: 689 PVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITPENSDVTFQFDEATQEHK 748

Query: 569 VI-REVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           VI  EV P+DAG +  +AKN +G       ++V
Sbjct: 749 VIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMV 781



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 10/129 (7%)

Query: 1340 SKSASLTIKKVENTDAGIYKLRL--ENNCGHADV-EMNVTILDK-----PSPPGKPNILE 1391
            +K+   T K    T+   Y+ R+  EN  G +   E + T   K     P  P  P + +
Sbjct: 5228 TKTTDFTFKVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFTAKLPFGVPGAPDTPELTD 5287

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449
            I   S+ + W  P + G S I+ Y VE ++  +T W  VK+  I   + ++ N++ ++  
Sbjct: 5288 IKDFSLTVKWLAPTSDGGSPILGYFVEQKDQFSTRWQRVKSSPILDLKFTVTNVQDDAEC 5347

Query: 1450 RFRAYAVNE 1458
             F   A+N+
Sbjct: 5348 EFHVIAINK 5356



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 10/114 (8%)

Query: 815  ETSAVITVEEPTEENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            E S  + VE+P     +P   ++ RF++ IT++   T ++       P P+++W +N + 
Sbjct: 8453 EPSNTVMVEDPA---VKPKFNLDARFEKVITIRAGHTFRIDIPYKATPTPTVSWTQNGDT 8509

Query: 873  ISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDV 925
            +  S  IT   D  N    +T   +E  DSGDY   ASN AG+ +    VT++V
Sbjct: 8510 VQKSNRIT--IDSNNYGTTLTARTAERTDSGDYVIRASNKAGEDT--VTVTVNV 8559



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 21/186 (11%)

Query: 1017  PEFIRKLQDFEVKEKDVAILEVEI----NSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
             P+ IR L+D E     +  L  ++          V W  +   +KP  + + +E+ G + 
Sbjct: 10783 PQLIRPLEDQECGFSFIMPLSFQVAEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDG-VH 10841

Query: 1073  KLYIRNTSVHDEGEYSCILRDE------SCTAEVTVVELP-------PEIITRLQNQKVN 1119
              L I  T+  D+G+Y+  + ++       C  +V  + L        P     L++  + 
Sbjct: 10842 TLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIV 10901

Query: 1120  KGNKATFEIELTK-GDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEY 1176
             +G+ A  + ++T   +  +RWFKD  EI    H  I+   D +   L I +  L DAG Y
Sbjct: 10902 EGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTY 10961

Query: 1177  SCEVGN 1182
             +C   N
Sbjct: 10962 TCLASN 10967



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 6/115 (5%)

Query: 1358 YKLRLENNCGHA--DVEMNVTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
            +++  EN  G +    E++VT     + P  P   N+     +S  + W  P++ G S I
Sbjct: 2997 FRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRESPTSATVKWSPPKSDGGSEI 3056

Query: 1413 IYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
              YV+E +E  +  W  V ++ T+T  +++ L    +  FR  AVN+      S+
Sbjct: 3057 TGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQ 3111



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 3/127 (2%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F+ KPKA    EG   +    +   P P+I +    +EI P EN  V  + D     
Sbjct: 688 PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITP-ENSDVTFQFDEATQE 746

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             +    V     G Y V+A N  GE    + + +    + P ++++   S+  R  +  
Sbjct: 747 HKVIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMVT--PRPPEELMKRKMSLKARASQQE 804

Query: 753 ILSAQVV 759
           I   + +
Sbjct: 805 IFEDEEI 811



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 18/172 (10%)

Query: 1507  GVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
             G+P+PKV WY + + LK     +    +                 Y     N +G + T 
Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATK 10870

Query: 1563  CVVGIQQKPVITISNEDIKQKH---KVGDEWLV-------TAVIEGIPPPEVIWYKNGNK 1612
             C + + +  +     +D ++ H    + D ++V          + G+P P + W+K+  +
Sbjct: 10871 CRLDVNE--LFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKE 10928

Query: 1613  LENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             + + + Y+I   E  +T  + I+E     +  YT  ASN  G  S +  ++V
Sbjct: 10929 IFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 50/212 (23%), Positives = 85/212 (40%), Gaps = 21/212 (9%)

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAI 684
           AD+L       +K P+ +   E   +   C L     + D+ W   G+ +  D+   +  
Sbjct: 589 ADLLLRETIKITKPPEDEDSRERQSVKFVCELTGDAAKADVKWKKGGQVVRKDKRHKIIN 648

Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
           E       S L I ++     G Y+V+  N E    +P  L ++    +PP      K++
Sbjct: 649 EG----LVSTLVIEDLSPSDAGKYSVLVDNME----MPFTLSVQA--LKPPVFTTKPKAV 698

Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV------- 797
             ++G S I    + G P P I + K+ K +   P  SD         +  KV       
Sbjct: 699 DTQEGMSAIFRYVIAGYPVPEIKFTKDWKEI--TPENSDVTFQFDEATQEHKVIFHEVTP 756

Query: 798 KDEGVYTLKAENSEG-IAETSAVITVEEPTEE 828
           KD G Y + A+N  G + +  +++    P EE
Sbjct: 757 KDAGKYLVIAKNESGEVKQAVSMMVTPRPPEE 788



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
           ++  PV   P  + +     F E+L+P     G T +  C+V       + W +   ++K
Sbjct: 313 VEAAPVKAVPEKKLKPEEWKFTEELKPAKGFKGDTCELVCEVND-ENAIVEWVKHGKVLK 371

Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           PS  +++  +D     LVI++  P D   +TC        AS   ++ V+
Sbjct: 372 PSDKYELK-EDGTKRILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPVK 420



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G    +E     IP P + W F G  + P  +I +    D     S + + NV+K   G 
Sbjct: 8186 GESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRI----DTSNRASTITVKNVEKANGGR 8241

Query: 708  YTVVAVNREGEASLPIVLKI 727
            YT+   N  G  SL + +++
Sbjct: 8242 YTINLKNTAGAESLDVEVRV 8261



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 13/164 (7%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVV 1284
             V WY +   ++    +    +    TL I   TE D+ +YT  + +   +  TK +++V 
Sbjct: 10817 VKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVN 10876

Query: 1285  E-FPPKIVDYE--------REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
             E F  K  DY         R+  I  GS   L       P+PN  W  + K I   +H  
Sbjct: 10877 ELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYS 10936

Query: 1336  PSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
                  D ++ SL I++    DAG Y     N  G    +  V +
Sbjct: 10937 IEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 52/243 (21%), Positives = 99/243 (40%), Gaps = 19/243 (7%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVRQ 748
            + +++T++++     + V AVN+ G++  P+     +K+K     P    +PL + +   
Sbjct: 8026 TTVRVTSLQEGASYVFRVFAVNKIGDSE-PLETKETIKLKKKYDVPEAPSKPLVTNVTSD 8084

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKA-----LPTKSDGDT-HSITILKPKKVK-DEG 801
              ++   +       P   +    K   +     + T S G T H I    P+ ++ +E 
Sbjct: 8085 SVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRI----PRLMRGEEY 8140

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNP 860
             + + AEN  G    S   +     E+    P F  RF E I  K   + ++    T  P
Sbjct: 8141 EFRVSAENRAGPGPASTP-SAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIP 8199

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
             P++TW  +   + PS  I  +       + + NV+ + + G Y     N+AG  S    
Sbjct: 8200 TPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVE-KANGGRYTINLKNTAGAESLDVE 8258

Query: 921  VTI 923
            V +
Sbjct: 8259 VRV 8261



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 2/94 (2%)

Query: 518   PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
             P H   G  +  +    G PRP I W R    +     F++     +  TL+IR +  ED
Sbjct: 10098 PIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT-TLIIRGITKED 10156

Query: 578   AGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSE 610
             AG ++ VA N  G  + + ++ I+  P S    E
Sbjct: 10157 AGKYSVVASNELGHDTCSIQVNILRHPDSPRNLE 10190



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%)

Query: 503  SEEQSMAPIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            +E+ ++ P F  +   P     G + + E    G P P +TW      +KPS   ++  D
Sbjct: 8164 AEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRI--D 8221

Query: 562  DDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              N  +T+ ++ V   + G +T   KN AG  S   E+ V
Sbjct: 8222 TSNRASTITVKNVEKANGGRYTINLKNTAGAESLDVEVRV 8261



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/135 (21%), Positives = 57/135 (42%), Gaps = 3/135 (2%)

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            V  + A  +E     ++   V E     A P + I   Q   V E  T   + +++ +P 
Sbjct: 9522 VTAVNAAGNESDPSRASESFVAESQLPGAAPSILIE-IQNAMVAEGQTGMFMCKISGSPK 9580

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            P ++W  +   + P        D    ++V+ +V ++ ++G Y  +A N  G     A +
Sbjct: 9581 PKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSV-TDYETGMYTIIAKNKHGSVRSSAEL 9639

Query: 922  TID-VEKVTFVKHLQ 935
             I    +++  +HLQ
Sbjct: 9640 LIQRPPQLSIDRHLQ 9654



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 6/115 (5%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
            V+W KDGS +Q S+ I++    +   + I +C  +D G +  +V N+  +  +T+    +
Sbjct: 7907 VKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSNTAGSDAITIRVQVL 7966

Query: 1197 NFTLRLPEFILVP---ANTDAYLTVEIPDET--LDVTWYKKKSVIEDTEKFTLIS 1246
            +     P   LV     +TD +L+ + P +T    +T Y  +   ED   +T ++
Sbjct: 7967 D-RPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLT 8020



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSD-GDTHSITILKPKKVKDE 800
            +M+VR G +  L       P+PT+ W K+   ++A    K D  D  +I  +K    +DE
Sbjct: 7884 TMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDE 7943

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
            G + L   N+ G    S  IT+     +  E P
Sbjct: 7944 GSFKLDVSNTAG----SDAITIRVQVLDRPEQP 7972



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTFT 582
            G+T++      G P P++ W R  A I  S+D + + +  DN   + IR V   D G F+
Sbjct: 9168 GNTLRLLVPYTGCPSPKVEWHRHDARI--SEDTRTHIETRDNRTQITIRNVVRGDTGKFS 9225

Query: 583  CVAKNAAGFASSTTEL-IVEAP 603
                N AG  ++   + +++ P
Sbjct: 9226 ITLTNEAGQETAIIRVNVIDVP 9247



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 19/69 (27%), Positives = 30/69 (43%)

Query: 1594  AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
             A I G+P P+V WY     L+    Y+   ++    + I         +YT E SN  G+
Sbjct: 10807 AEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGS 10866

Query: 1654  SSVEVTLKV 1662
              + +  L V
Sbjct: 10867 IATKCRLDV 10875



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284
             +TW++ K  +  + K+ ++ D  K TLI++    DD  EYTC  +++   +T+   ++V 
Sbjct: 10678 ITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEFDDIDEYTCKAVNSYGHATSSASLDVQ 10737

Query: 1285  EFPPKIVDYEREYR 1298
                 K +D   E R
Sbjct: 10738 LLDAKELDSRGERR 10751



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            T++ +  A  FV+ L      +   T+  EC++     P   W++   +I      ++  
Sbjct: 1074 TADLKVQAAEFVKPLNNTSAAEYDETIVLECELSNELVP-CQWYKDDVLITVGPKVEVI- 1131

Query: 561  DDDNVATLVIREVFPEDAGTFTCV 584
            DD     LV+ +V PED G F CV
Sbjct: 1132 DDGKKRKLVLHDVRPEDTGNFRCV 1155



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 3/94 (3%)

Query: 833   PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
             P FI   +     E    +    V+    P ITW+R  + +  S      +D     L++
Sbjct: 10647 PKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIV 10706

Query: 893   TNVDSEIDSGD-YKCVASNSAGKSSHGARVTIDV 925
                DSE D  D Y C A NS G ++  A + + +
Sbjct: 10707 Q--DSEFDDIDEYTCKAVNSYGHATSSASLDVQL 10738


>UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin
            - Gallus gallus (Chicken)
          Length = 8074

 Score =  344 bits (845), Expect = 2e-92
 Identities = 348/1452 (23%), Positives = 607/1452 (41%), Gaps = 102/1452 (7%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +LEG  P F+ K +     E  +++L+C +     P + W+  G+ I P +N  V I++D
Sbjct: 6250 VLEG-DPYFTGKLQDYTAVEKDEVILQCEISKADAP-VKWMKDGKPITPSKN--VVIKAD 6305

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                  +LK     K   G YT      +  A+L I       E    ++I PL S+ V 
Sbjct: 6306 GKKRILILK--KALKKDIGQYTCDCGTDQTSANLNI-------EDRDIEIIRPLYSVEVI 6356

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYT 804
            + E+     ++         W    +P+   P    K +G  H +T+   +  +  GV  
Sbjct: 6357 ETETARFDIEI-SEEGVHGNWKLKGEPLTESPDCEIKEEGKKHFLTLYNVRLDQAGGV-D 6414

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             +A N    A++ A + V+ P       PL     +++TV    +      ++   +P +
Sbjct: 6415 FQAAN----AKSGAHLRVK-PRVIGLLRPL-----KDVTVTAGESATFDCELSYEGIP-V 6463

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             WY   + + PS+ +    +G    L++ +V    D+G+    A +   +    A + + 
Sbjct: 6464 EWYLQGKKLEPSDKVVTRAEGRAHTLILRDVKLT-DAGEVSLTAKDFRTQ----ANLFVK 6518

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXX 983
               V F K L+     EE  T ILEC+ S      KW+ N +EI      +II EGR   
Sbjct: 6519 EPPVEFTKPLEDQ-TVEEEATAILECEVSRENAKVKWFKNGEEIHKTKKYDIISEGRVRK 6577

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV-AILEVEINS 1042
                     D     C  KD +TS  L V+    EF+R L D EVKEK + ++L V+  +
Sbjct: 6578 LIIHGCTLDDAKTYTCDAKDFKTSCFLNVEPLRVEFLRPLTDLEVKEKRICSVLNVKFLA 6637

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            +   V W +DG  I+ +K +YD   +G  R L I      DE EY+C  +    +  +TV
Sbjct: 6638 QGVKVKWFKDG--IEIEKAEYDIISKGAERILVISKCLFDDEAEYACEAKTARTSGLLTV 6695

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            +E        L + +VN+        E++K +A V WFK   E+      +   DG+K+ 
Sbjct: 6696 IEEEAVFTKNLHDLEVNENETVRLICEISKPNAEVTWFKGDEEVPDGGRFEYISDGRKRI 6755

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            L I +   +DAG+Y+C++ +S  T  LTV E +  F  R P+ + V     A     +  
Sbjct: 6756 LVIRNAHPEDAGKYTCKLPSSSTTGKLTVHELAAEFLTR-PQNLEVLEGDKAEFACSVSK 6814

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            E + V W    +V+E  +K+ +ISD KKRTL+++     D  +YT ++ +AK+T +L V 
Sbjct: 6815 EAITVQWLWGDTVLEPGDKYDIISDGKKRTLVVKDSVVGDAGKYTVMVGEAKATARLTV- 6873

Query: 1283 VVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSID 1339
             +E   K  DY   ++  +  G ++    +        ++W  N + I    K+     D
Sbjct: 6874 -IE---KTQDYNSLKDQEVNEGQEIIFNCEVNK-EGAKEKWYKNGEAIFDSAKYIIVQKD 6928

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
                +L I+  +  D   Y + L N+ G HA+    +T+L++     +P           
Sbjct: 6929 LVY-TLRIRDTQLKDQATYSISLSNHRGEHAESSAALTVLEEGLRIVEP----------- 6976

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
               ++ E     T+ ++    +   T +W   KN  +   + + L     Y+  +  + +
Sbjct: 6977 --LEDIETMEKKTVTFWCKVNRLNATLKW--TKNGEEITFNKRILYKIDKYK-HSLIIKD 7031

Query: 1459 VDISDASE---TTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKV 1513
                D  E   T    K + E  I     +  + L++ T    +D   TC      +  V
Sbjct: 7032 CGFKDEGEYTVTAGQDKSVAELLITEAPADFIEHLQDQTVTEFDDAVFTCQLSK-EKASV 7090

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             WYR+G+++K  K     +                +C       + ++   + +++ PV 
Sbjct: 7091 KWYRNGREIKEGKKYQFEKDGNLHRLIIKDCRLDDECEYSCGVDDRKSRARLFVEEIPVE 7150

Query: 1574 TISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
             I   +D+ +       ++     +G+   EV W +N   +    ++ + ++ K   +++
Sbjct: 7151 IIRPPQDVYEAPGADVIFMAELNKDGV---EVKWLRNNMIIIQGDKHQMMSEGKVHRLQV 7207

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             E+K     +Y   A +    + +E+      K       V +      +V  +  P  +
Sbjct: 7208 CEIKPRDQGEYRFIAKDKEARAKLELAAAPRIKTGDQNLVVDVGNPLTMTVPYDAYPRAE 7267

Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
               L+      E+  P         D   D  T+ I +  ++ +  ++V+ +N    +EA
Sbjct: 7268 AEWLKG-----EESLPTTT-----VDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQAEA 7317

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGK 1811
              +  ++     DVP            D E V + W   E +GGS II Y VE +  + K
Sbjct: 7318 FINVEVI-----DVPGPVRNLEVTEIYDGE-VGLAWQEPESDGGSKIIGYVVERRDIKRK 7371

Query: 1812 KWKXXXXXXX----XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
             W                +QK  +   Y FR+ ARN +GT  P  ++  +        P 
Sbjct: 7372 TWIVVTDHAENCEYTVTGLQKGGVE--YLFRVSARNRVGTGEPVETERPVEAKSKFEVPG 7429

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
             P+N  V++      TL W  PE +GGSPIT Y+IE +      W   +T G       +
Sbjct: 7430 PPQNVEVTDVNRFGRTLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVL 7489

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
             ++ E +E  FR+ A+N VGV  P+  +++V++      PS     L+        V  +
Sbjct: 7490 TDVVENEEYFFRVRAQNMVGVGKPSHPTRAVKITDPIERPS-GNINLDHSDQTKTSVQLT 7548

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P  DGG+P+LGY I  ++     W+      V    F +  L    +Y  R+ A N 
Sbjct: 7549 WEPPLEDGGSPILGYIIERKEEGTDKWIRCNPKLVPACAFKVTGLKAGSSYYYRVSAENA 7608

Query: 2047 IGLSEPLESDEP 2058
             G+S+P E+  P
Sbjct: 7609 AGVSDPAEAIGP 7620



 Score =  296 bits (727), Expect = 4e-78
 Identities = 287/1205 (23%), Positives = 498/1205 (41%), Gaps = 91/1205 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  +++L+P     G   +F   + G P+P+++W++    + P    +  +D     TL+
Sbjct: 2966 PQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEY-TLL 3024

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            + E FPED+  +TC AKN  G A+++  L VE P      E+ V                
Sbjct: 3025 LIETFPEDSAVYTCEAKNDYGVATTSASLSVEIP-EVVSPELEVPV-------------- 3069

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
               PP      +     EG     +CR+    +  ++W  K  EI P     +    D +
Sbjct: 3070 --YPPAVIVPLRDAVTSEGQSARFQCRVTG-TDLKVSWYSKDREIKPSRFFRMTQFEDTY 3126

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP--------- 740
                 L+I       EGTYT VA N  G+ +   +LK++  EK   + +E          
Sbjct: 3127 Q----LEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVA 3182

Query: 741  ------LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITI 791
                  L+ + V        + +V   P     W K  + +        +S     ++ I
Sbjct: 3183 PILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEI 3242

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTI 850
             +P +V D G Y+ KA N  G   ++A +TV        EPP FI +      VK+  + 
Sbjct: 3243 PRP-QVVDCGEYSCKASNQHGSVSSTAFLTV-------TEPPRFIKKLDSSRLVKQHDST 3294

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
            +   +V  +P   +TWY+    I PSE  + +F      L + N+  E DSGDY C A N
Sbjct: 3295 RYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVLEMHNLSVE-DSGDYSCEAQN 3353

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS 968
             AG +S    + +      F K      +T +G  V LEC+   T      WY +K+EI 
Sbjct: 3354 PAGSASTSTSLKVKAPP-AFTKK-PHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIR 3411

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTML--VVKETIPEFIRKLQD 1025
                 +++ E              DVG   C  V D  + + +  V     P F++KL D
Sbjct: 3412 SSKKYKVMSENYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSD 3471

Query: 1026 FEVKEKDVAILEVEI-NSETADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
              V   +   L+  +  ++   V+W +D GEII+  +N +      ++  L I N    +
Sbjct: 3472 VTVVVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLW-ISYSENVASLKIGNAEPTN 3530

Query: 1084 EGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VR 1138
             G+Y C +++++    C A++TV+E P  I+ +    KV  G+  T E  +     L  R
Sbjct: 3531 AGKYICQIKNDAGFQECFAKLTVLE-PAVIVEKPGPVKVTAGDSCTLECTVDGTPELTAR 3589

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEP 1194
            WFKDG+E+   +  +++   K   LKI +  L+D+GEY+ E    VG S CTA L V + 
Sbjct: 3590 WFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQVSDR 3649

Query: 1195 SI--NFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
             +  +FT +L E       + A L  ++     + V+W+     I   +K+         
Sbjct: 3650 IMPPSFTRKLKE-TYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTC 3708

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            +L +    E D   Y+C   +   + +    + V  PP  V     + +  G ++T    
Sbjct: 3709 SLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFVKKPEPFNVLSGENITFTSI 3768

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
             +  P    +W   S  +        ++    A L +  V+   +G Y  ++ N  G   
Sbjct: 3769 VKGSPPLEVKWFRGSIELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAGKIS 3828

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
               ++ + +      K N L ++     I   E   TG   I    V +++       S 
Sbjct: 3829 CTTHLFVKEPAKFVMKVNDLSVEKGKNLIL--ECTYTGTPPI---SVTWKKNGVILKHSE 3883

Query: 1431 K-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
            K +IT T+TS      NS    +      ++ +D+ +   +  +   T ++ P    PL+
Sbjct: 3884 KCSITTTETSAILEIPNSKLEDQGQYSCHIE-NDSGQDNCHGAI---TILEPPYFVTPLE 3939

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENR-XXXXXXXXXXXXX 1545
             +     +   L C   G P+  V+WY+   KL+   T K  ++N+              
Sbjct: 3940 PVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDS 3999

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEV 1604
              Y C   N  GE  +S ++ +Q++ +       ++  H+ VG        I G  P EV
Sbjct: 4000 GEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEV 4059

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W+K+  +++ D   + +  +  ++++I +  +S   +YT  ASN  GT+S    L + +
Sbjct: 4060 SWFKDNVRVKEDYNVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTE 4119

Query: 1665 KPSKP 1669
              + P
Sbjct: 4120 GKTPP 4124



 Score =  271 bits (665), Expect = 1e-70
 Identities = 279/1206 (23%), Positives = 476/1206 (39%), Gaps = 71/1206 (5%)

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            ++P    P  E     P  +  LR   T +G + +F+C+V G    +++W+ +   IKPS
Sbjct: 3056 EIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGTDL-KVSWYSKDREIKPS 3114

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            + F+M   +D    L I E +PED GT+T VA N+ G  +ST  L +EAP      ++  
Sbjct: 3115 RFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLE- 3172

Query: 614  XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                         ++   + P   ++ +   V         C +   P     W   G E
Sbjct: 3173 ----------EEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGRE 3222

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
            I   +  S+   +    Y S L+I   +    G Y+  A N+ G  S    L +     E
Sbjct: 3223 IYDGDKYSIRSSN----YLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTVT----E 3274

Query: 734  PPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
            PP+ I+ L  S +V+Q +S     +V G+P   +TW K    +      S     S+ +L
Sbjct: 3275 PPRFIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVL 3334

Query: 793  KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            +     V+D G Y+ +A+N  G A TS  + V+ P       P F  +   +   +   +
Sbjct: 3335 EMHNLSVEDSGDYSCEAQNPAGSASTSTSLKVKAP-------PAFTKKPHPVQTLKGSDV 3387

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
             L   +   P   I+WY++   I  S+      +     + I NVD+  D G+Y C A N
Sbjct: 3388 HLECELQGTPPFQISWYKDKREIRSSKKYKVMSENYLASIHILNVDTA-DVGEYHCKAVN 3446

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEI- 967
              G  S    VT+     TFVK L        G+T+ L+   + +  +S  W  +K EI 
Sbjct: 3447 DVGSDSCIGSVTLRAPP-TFVKKLS-DVTVVVGETIELQAAVEGAQPISVLWLKDKGEII 3504

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQ 1024
               ++  I                 + G   C +K+         K T+ E    + K  
Sbjct: 3505 RESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVLEPAVIVEKPG 3564

Query: 1025 DFEVKEKDVAILEVEINSETADVV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
              +V   D   LE  ++  T ++   W +DG  +    +KY       +  L I N  + 
Sbjct: 3565 PVKVTAGDSCTLECTVDG-TPELTARWFKDGNELSTD-HKYKISFFNKVSGLKILNAGLE 3622

Query: 1083 DEGEYSCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDA- 1135
            D GEY+  +++     SCTA + V +  +PP    +L+      G+ A  E ++      
Sbjct: 3623 DSGEYTFEVKNSVGKSSCTASLQVSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPI 3682

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV 1191
            LV WF DG EI   +  Q T+      LK+      D G YSC      G+ +C+A L+V
Sbjct: 3683 LVSWFHDGQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSV 3742

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
             EP  +F  +   F ++      + ++      L+V W++    +    K  +       
Sbjct: 3743 REPP-SFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQDSVA 3801

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
             L +         +YTC + +          + V+ P K V    +  +++G ++ L   
Sbjct: 3802 ELELFDVQPLQSGDYTCQVSNEAGKISCTTHLFVKEPAKFVMKVNDLSVEKGKNLILECT 3861

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
            Y   P  +  W  N  I+K  +    +    SA L I   +  D G Y   +EN+ G  +
Sbjct: 3862 YTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIENDSGQDN 3921

Query: 1371 VEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
                +TIL+ P    P +P  + +  S+   C  +   T    + +Y  + +   T    
Sbjct: 3922 CHGAITILEPPYFVTPLEPVQVTVGDSASLQC--QVAGTPEMIVSWYKGDTKLRGTA--- 3976

Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
            +VK   K Q +        S     Y + +V+ +    T+     ++E K+  P+  + L
Sbjct: 3977 TVKMHFKNQVATLVFSQVDSDDSGEY-ICKVENTVGEATSSSLLTVQERKLP-PSFTRKL 4034

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXX 1544
            +++       +   C   G    +V+W++D  ++K     +    +N             
Sbjct: 4035 RDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQILKTDKSL 4094

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPE 1603
               Y C A N  G   +S  + + +       +  I     + G+       I G  P  
Sbjct: 4095 MGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIR 4154

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            V W K+  ++     Y I+  E T+ + I  + R  S KYT  ASN  G  S    L V 
Sbjct: 4155 VTWAKDNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVK 4214

Query: 1664 DKPSKP 1669
            ++ + P
Sbjct: 4215 ERKTPP 4220



 Score =  264 bits (647), Expect = 2e-68
 Identities = 343/1431 (23%), Positives = 565/1431 (39%), Gaps = 118/1431 (8%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F+K      V+E   + L C  ++ P  ++ W FKG+E VPD      I         +L
Sbjct: 6702 FTKNLHDLEVNENETVRLICE-ISKPNAEVTW-FKGDEEVPDGGRFEYISDGRKR---IL 6756

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             I N      G YT    +      L  V ++       PQ +E L      +G+    +
Sbjct: 6757 VIRNAHPEDAGKYTCKLPSSSTTGKLT-VHELAAEFLTRPQNLEVL------EGDKAEFA 6809

Query: 756  AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              V      T+ W   +   +P       SDG   ++ ++K   V D G YT+      G
Sbjct: 6810 CSV-SKEAITVQWLWGDTVLEPGDKYDIISDGKKRTL-VVKDSVVGDAGKYTVMV----G 6863

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
             A+ +A +TV E T++        N  ++  V E   I     V +       WY+N E 
Sbjct: 6864 EAKATARLTVIEKTQD-------YNSLKDQEVNEGQEIIFNCEVNKEGAKE-KWYKNGEA 6915

Query: 873  ISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHG-ARVTIDVEKVTF 930
            I  S         +++   +   D+++ D   Y    SN  G+ +   A +T+  E +  
Sbjct: 6916 IFDSAKYI--IVQKDLVYTLRIRDTQLKDQATYSISLSNHRGEHAESSAALTVLEEGLRI 6973

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            V+ L+   ET E KTV   C+ +   +T KW  N +EI+  + R + +  +         
Sbjct: 6974 VEPLE-DIETMEKKTVTFWCKVNRLNATLKWTKNGEEIT-FNKRILYKIDKYKHSLIIKD 7031

Query: 990  -XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
                D G         ++   L++ E   +FI  LQD  V E D A+   +++ E A V 
Sbjct: 7032 CGFKDEGEYTVTAGQDKSVAELLITEAPADFIEHLQDQTVTEFDDAVFTCQLSKEKASVK 7091

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W R+G  IK  K KY FEK G++ +L I++  + DE EYSC + D    A + V E+P E
Sbjct: 7092 WYRNGREIKEGK-KYQFEKDGNLHRLIIKDCRLDDECEYSCGVDDRKSRARLFVEEIPVE 7150

Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            II   Q+     G    F  EL K    V+W ++   I   +  Q+  +GK  +L++ + 
Sbjct: 7151 IIRPPQDVYEAPGADVIFMAELNKDGVEVKWLRNNMIIIQGDKHQMMSEGKVHRLQVCEI 7210

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL--- 1225
               D GEY     + +  A L +        ++  +  LV  +    LT+ +P +     
Sbjct: 7211 KPRDQGEYRFIAKDKEARAKLELAAAP---RIKTGDQNLV-VDVGNPLTMTVPYDAYPRA 7266

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283
            +  W K +  +  T   T+ +     T  I +  + D+  Y  VL +  A++   + VEV
Sbjct: 7267 EAEWLKGEESLPTT---TVDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQAEAFINVEV 7323

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQ---AFPQPNDE-------WIVNSKIIKKCKH 1333
            ++ P  +          R  +VT + D +   A+ +P  +       ++V  + IK+   
Sbjct: 7324 IDVPGPV----------RNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVERRDIKRKTW 7373

Query: 1334 TKPSIDSKSASLTIKKVENTDAG-IYKLRLENNCGHAD---VEMNVTILDK---PSPPGK 1386
               +  +++   T+  ++      ++++   N  G  +    E  V    K   P PP  
Sbjct: 7374 IVVTDHAENCEYTVTGLQKGGVEYLFRVSARNRVGTGEPVETERPVEAKSKFEVPGPPQN 7433

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLK 1444
              + +++     + W+ PE  G S I  YV+E +   + +W         + S  + ++ 
Sbjct: 7434 VEVTDVNRFGRTLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVLTDVV 7493

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-------KPLKNITTEPNE 1497
             N  Y FR  A N V +   S  T   K+    +  S  +        K    +T EP  
Sbjct: 7494 ENEEYFFRVRAQNMVGVGKPSHPTRAVKITDPIERPSGNINLDHSDQTKTSVQLTWEPPL 7553

Query: 1498 DIELTCIFGGVPQPKVT----WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            +   + I G + + K      W R   KL  A A                    Y+  A 
Sbjct: 7554 EDGGSPILGYIIERKEEGTDKWIRCNPKLVPACA-------FKVTGLKAGSSYYYRVSAE 7606

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE------GIPPPEVIWY 1607
            N  G  + +  +G        +  +      K G E +V   I+      G P P   W 
Sbjct: 7607 NAAGVSDPAEAIGPLTADDPFVDLQWPLSAFKDGLEVIVPEPIKIRVPITGYPIPTATWS 7666

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
                 LE      + T    + + I   +R     YT+   N   + S E+ + V  +PS
Sbjct: 7667 FGDQVLEEGGRVTMKTTSTFAELVITPSERPDKGIYTLTLENPVSSVSGEIDVNVLARPS 7726

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
             P+   ++ ++SR +V + W+PP DDGG  +  Y IEK E     WIKV D   D E + 
Sbjct: 7727 APKELKVV-DVSRSTVQLSWEPPEDDGGSPVIDYIIEKREVSRKTWIKVMDHVIDQE-FS 7784

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L +  EY+FRV A N  G  E A   EPI +     VP             ++ +++
Sbjct: 7785 VPDLIQGKEYLFRVCACNKCGPGEPAYIDEPINMSAPATVPDPPENVKWRNP-TSKGIFL 7843

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEG-KKWKX-XXXXXXXXARIQKLSINTTYQFRIYARNE 1844
            TW P + +GG+ I  Y VE  Q G  KW+            + KL     Y +R+ A N 
Sbjct: 7844 TWEPPKYDGGARIKGYLVEKCQRGTDKWEICGEPVIETKMEVTKLKEGEWYAYRVKALNR 7903

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
            IG S P    D I        P    +  +    +     K   P    G P    I   
Sbjct: 7904 IGASKPSKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKAGTKIELPAKITGKP-EPQITWT 7962

Query: 1905 KTVKGKSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            K  K       +T+  + +     I + K  D   + I A N+ G +      +V L+K 
Sbjct: 7963 KAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYIIEAVNSSGRATAVVEVNV-LDK- 8020

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
               P PP A  ++  + +   + +W  P  DGG+ +  Y +  R     +W
Sbjct: 8021 ---PGPPAA-FDVSEITNESCLLTWNPPRDDGGSKITNYVLEKRATDSEIW 8067



 Score =  234 bits (573), Expect = 2e-59
 Identities = 244/1068 (22%), Positives = 431/1068 (40%), Gaps = 62/1068 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F+KKP      +GSD+ LEC L   P   I+W     EI   +   V  E+    Y 
Sbjct: 3369 PPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSEN----YL 3424

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + + I NV     G Y   AVN  G  S    + ++     PP  ++ L  + V  GE++
Sbjct: 3425 ASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRA----PPTFVKKLSDVTVVVGETI 3480

Query: 753  ILSAQVVGNPRPTITWCKN-NKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809
             L A V G    ++ W K+  + ++         + ++  LK    +  + G Y  + +N
Sbjct: 3481 ELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKN 3540

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G  E  A +TV        EP + + +   + V    +  L   V   P  +  W+++
Sbjct: 3541 DAGFQECFAKLTV-------LEPAVIVEKPGPVKVTAGDSCTLECTVDGTPELTARWFKD 3593

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID--VEK 927
               +S       +F  +   L I N   E DSG+Y     NS GKSS  A + +   +  
Sbjct: 3594 GNELSTDHKYKISFFNKVSGLKILNAGLE-DSGEYTFEVKNSVGKSSCTASLQVSDRIMP 3652

Query: 928  VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             +F + L+++Y  + G + +LEC+   S  +   W+H+ +EI+  D  +           
Sbjct: 3653 PSFTRKLKETY-GQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLK 3711

Query: 986  XXXXXXXDVGVIKC----IVKDQETSTMLVVKETIPEFIRKLQDFEV-KEKDVAILEVEI 1040
                   D+G   C    +    E S  L V+E  P F++K + F V   +++    +  
Sbjct: 3712 VNGLQESDMGTYSCTATNVAGSDECSAFLSVREP-PSFVKKPEPFNVLSGENITFTSIVK 3770

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SC 1096
             S   +V W R G I     +K +   +  + +L + +      G+Y+C + +E    SC
Sbjct: 3771 GSPPLEVKWFR-GSIELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAGKISC 3829

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
            T  + V E P + + ++ +  V KG     E   T    + V W K+G  ++ S    +T
Sbjct: 3830 TTHLFVKE-PAKFVMKVNDLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSIT 3888

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
                   L+I +  L+D G+YSC +    G   C   +T+ EP    T   P  + V  +
Sbjct: 3889 TTETSAILEIPNSKLEDQGQYSCHIENDSGQDNCHGAITILEPPYFVTPLEPVQVTVGDS 3948

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC--- 1268
                  V    E + V+WYK  + +  T    +    +  TL+  +   DD  EY C   
Sbjct: 3949 ASLQCQVAGTPEMI-VSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVE 4007

Query: 1269 -VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
              + +A S++ L V+  + PP      R+     G  VT              W  ++  
Sbjct: 4008 NTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVR 4067

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GK 1386
            +K+  +   S     A L I K + +  G Y     N  G A     + + +  +PP   
Sbjct: 4068 VKEDYNVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFD 4127

Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLK 1444
              I  +D         E   +G   I + +  + QEI T     +  +  T   +I  + 
Sbjct: 4128 TPITPVDGIIGESADFECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAHLTILRVD 4187

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT--TEPNEDIELT 1502
               S ++  YA NEV     +        +KE K   PT  + L      TE NE ++L 
Sbjct: 4188 RGDSGKYTCYASNEVGKDSCTAQLN----VKERK-TPPTFTRKLSEAVEETEGNE-LKLE 4241

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTA---KATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGE 1558
                G     V+WY++ +++ ++   + +++N                 Y C   N+ G 
Sbjct: 4242 GRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGS 4301

Query: 1559 VETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            V  +  V I++     + ++ ++    + GD   ++  + G  P  + W K G ++   +
Sbjct: 4302 VLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASE 4361

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
              + +     +++ +  + +S S +Y  +ASN AGT +    + V +K
Sbjct: 4362 RCSFSFANGVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKEK 4409



 Score =  214 bits (523), Expect = 2e-53
 Identities = 240/1082 (22%), Positives = 435/1082 (40%), Gaps = 76/1082 (7%)

Query: 639  KPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            KP A   V E    + EC  VA PE +  WL  G+ +   +      +         L I
Sbjct: 2351 KPLADLTVAESQRAVFECE-VANPESEGQWLKNGKPLPMTDQYRAETDGVKRR----LNI 2405

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
               K    G Y+    + +  A L +         E  ++ + LK++ V + +  + S +
Sbjct: 2406 PAAKMDDMGEYSYEIASSKTSAKLHV---------EAVKIKKTLKNLTVTETQEAVFSVE 2456

Query: 758  VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            +         W KN   +++         G  H++ I K   V DE VY+ K     G  
Sbjct: 2457 LSHPDVKGALWIKNGVELESNDKYEISVKGTVHTLKI-KHCVVTDESVYSFKL----GKI 2511

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
              +A + VE            I + +++T  E   +     V+ + VP + W+  N  + 
Sbjct: 2512 GANARLHVETVK--------IIKKPKDVTALENAVVSFELSVSHDTVP-VRWFHKNVELK 2562

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             S+        +  +L++ N+ S  D+G+Y         K+       + VE +   K +
Sbjct: 2563 QSDKYKMISQRKVHKLMLHNI-SPADAGEYTAFVGQLECKAK------LFVETIHITKTM 2615

Query: 935  QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
             KS E  E KT   +C+ SH  V + W  N  EI   +  +I+ +G+            D
Sbjct: 2616 -KSIEIPETKTASFQCEVSHFNVPSVWLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSSED 2674

Query: 994  VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
                  +  +   S  L VK  +      L+D   +EKD    EV +N E     W ++G
Sbjct: 2675 SAEYTFVCGNDRVSATLTVKPIL--ITSMLEDINAEEKDTITFEVTVNYEGISYKWLKNG 2732

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRL 1113
              IK   +K     +     L IRN    D  EYS +    + +A + V     E    +
Sbjct: 2733 VEIK-STDKCQIRTKKLTHSLSIRNVHFGDAAEYSFVAGKAASSATLYVEARHIEFRKHI 2791

Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
            ++ KV +  +A FE E+++ D  V+W KDG E+Q  + +++  +    +L I    + DA
Sbjct: 2792 KDIKVVEKKRAIFECEISEPDVQVQWMKDGQELQIGDRMKIQREKYVHRLIIPSTKMSDA 2851

Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
            G+Y+   G +  +A L VE   +     + + I V     A +  E+ ++ ++  WYK  
Sbjct: 2852 GQYTVVAGGNTSSANLIVEGRDVRIR-SIRKEIQVIERQRAEIEFEVNEDDIEPQWYKDG 2910

Query: 1234 SVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
              I     E+++ + + +   + I + T  D  EYT V    +S+  L V   E PP+I+
Sbjct: 2911 IEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGRNRSSVVLYVNAPE-PPQII 2969

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               +   ++ G            PQP   W  + + +      K   D++  +L + +  
Sbjct: 2970 QELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETF 3029

Query: 1352 NTDAGIYKLRLENNCGHA--DVEMNVTILDKPSP----PGKPNILEID-----SSSINIC 1400
              D+ +Y    +N+ G A     ++V I +  SP    P  P  + +      +S     
Sbjct: 3030 PEDSAVYTCEAKNDYGVATTSASLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSA 3089

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNL--KTNSSYRFRA-YAV 1456
              +   TG    + +  + +EI  + +  +     T Q  I     +   +Y F A  +V
Sbjct: 3090 RFQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSV 3149

Query: 1457 NEVDIS-----DASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTCIFGGV 1508
             +V  +     +A E   Y K+ +E +++   +P + + L+ +    N   + TC     
Sbjct: 3150 GQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETT 3209

Query: 1509 PQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
            P  K  WY+ G+++    K +  +                   Y C A N HG V ++  
Sbjct: 3210 PNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAF 3269

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            + + + P   I   D  +  K  D       + G P  +V WYK   ++   ++Y+++  
Sbjct: 3270 LTVTEPPRF-IKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFV 3328

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            +  +V+ +  L    S  Y+ EA N AG++S   +LKV   P+  + P  ++ +    V 
Sbjct: 3329 DSVAVLEMHNLSVEDSGDYSCEAQNPAGSASTSTSLKVKAPPAFTKKPHPVQTLKGSDVH 3388

Query: 1685 IE 1686
            +E
Sbjct: 3389 LE 3390



 Score =  204 bits (498), Expect = 2e-50
 Identities = 240/1119 (21%), Positives = 441/1119 (39%), Gaps = 91/1119 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F KKP+   V  G +I     +   P  ++ W     E+ P    ++ ++  +    
Sbjct: 3745 PPSFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQDSV---- 3800

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L++ +V+  Q G YT    N  G+ S    L +K    EP + +  +  + V +G+++
Sbjct: 3801 AELELFDVQPLQSGDYTCQVSNEAGKISCTTHLFVK----EPAKFVMKVNDLSVEKGKNL 3856

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810
            IL     G P  ++TW KN   +K     S   T +  IL+    K++D+G Y+   EN 
Sbjct: 3857 ILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIEND 3916

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G       IT+        EPP F+   + + V    +  L  +V   P   ++WY+ +
Sbjct: 3917 SGQDNCHGAITI-------LEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVSWYKGD 3969

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-- 928
              +  + T+  +F  +   LV + VDS+ DSG+Y C   N+ G+++  + +T+   K+  
Sbjct: 3970 TKLRGTATVKMHFKNQVATLVFSQVDSD-DSGEYICKVENTVGEATSSSLLTVQERKLPP 4028

Query: 929  TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            +F + L+  +ET  G  V  +C    S  +   W+ +   +    +              
Sbjct: 4029 SFTRKLRDVHETV-GLPVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQI 4087

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040
                   +G   C   +      +S  LV+ E  T P F   +   +    + A  E  I
Sbjct: 4088 LKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHI 4147

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
            + ++   V W +D + I+   N Y      +   L I      D G+Y+C   +E    S
Sbjct: 4148 SGTQPIRVTWAKDNQEIRTGGN-YQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDS 4206

Query: 1096 CTAEVTVVELP-PEIITRLQNQKVNK--GNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151
            CTA++ V E   P   TR  ++ V +  GN+   E  +     L V W+K+  E+  S H
Sbjct: 4207 CTAQLNVKERKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPH 4266

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFIL 1207
             +++       L I      DAG Y+C+V N      CT+ + + EP        P   L
Sbjct: 4267 CEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQP---L 4323

Query: 1208 VPANTDAYLTVEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
             PA T+   T+++       E + + W K    I  +E+ +         L +   T+ D
Sbjct: 4324 QPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSD 4383

Query: 1263 QCEYTCVLLD--------AKSTTKLKVEVVEFPPK--------IVDYEREYRIKRGSDVT 1306
              EY C   +        +K T K K  +V    K         V   +  ++   +  T
Sbjct: 4384 SGEYVCKASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVAT 4443

Query: 1307 LLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
             +      P PN +W+    + + +            A L IK    TD+G+YK    N 
Sbjct: 4444 FIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTTKTDSGLYKCVAFNQ 4503

Query: 1366 CGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYV--VEYQEI 1422
             G  +  +N+ + ++     + ++  ++         DE +      ++  V   EY++ 
Sbjct: 4504 HGEIERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDILELLKNVDPKEYEKY 4563

Query: 1423 DTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKI 1479
                 I+  + + +    ++  +   S+R       +    D  E  E    I++  T+ 
Sbjct: 4564 ARMYGITDFRGLLQAFELLKQTREEESHRLEIELTEKAQKED-QEFEELVAFIQQRLTQT 4622

Query: 1480 QSPTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
            +  T+ + ++N T   +ED    C I    P+ K++WY+  +KL ++   Y+ +      
Sbjct: 4623 EPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLDSSD-KYKIK------ 4675

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTA 1594
                      K     D G     C   I    +  I     +  H    K G+   ++ 
Sbjct: 4676 IEGDRHILKIKNCQLEDQGNYRIVCGPHIASARLTVIEPAVERHLHDTTFKEGNTCTLSC 4735

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
                IP  +  WY+NG  ++    Y+    +K   + IK+++     +YT +  N   T+
Sbjct: 4736 QF-SIPNAKSQWYRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLDNLETTA 4794

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             + +  +        +  V+      +S T E +   DD
Sbjct: 4795 DLTIEAEPIQFTKSIQNIVVS---EHQSATFECEVSFDD 4830



 Score =  183 bits (446), Expect = 4e-44
 Identities = 171/703 (24%), Positives = 311/703 (44%), Gaps = 56/703 (7%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PPTF++K  +A    EG+++ LE R+       ++W    +E+    +  ++ +++  + 
Sbjct: 4219 PPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLL- 4277

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L I +V +   G YT    N  G       + I+   K+PP   +PL+     +G++
Sbjct: 4278 ---LHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIRE-PKKPPVFDQPLQPAATEEGDT 4333

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809
            + LS  V G+    I W K  + ++A    S    + + +L+   V   D G Y  KA N
Sbjct: 4334 LQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSDSGEYVCKASN 4393

Query: 810  SEGIAETSAVITVEEPT-------EENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPV 861
              G     + +TV+E         + + E  L F++  Q I V EK     +A+V  +P+
Sbjct: 4394 VAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVATFIAKVGGDPI 4453

Query: 862  PSITWYRNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P++ W +    ++      I Q   G+  +L I +  ++ DSG YKCVA N  G+     
Sbjct: 4454 PNVKWMKGKWRQLNQGGRIIIQQ-RGDEAKLEIKDT-TKTDSGLYKCVAFNQHGEIERSV 4511

Query: 920  RVTIDVEKVTFV--------KHLQKSYETEEGKTV-ILECQTSHTVSTKWYHNKKEISGM 970
             + ++  K   V        K +    + +E +T+ ILE   +  V  K Y     + G+
Sbjct: 4512 NLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDILELLKN--VDPKEYEKYARMYGI 4569

Query: 971  -DHREIIQEGRXXXXXXXXXXXX-DVGVI-KCIVKDQETSTMLV-----VKETIP-EFIR 1021
             D R ++Q                ++ +  K   +DQE   ++      + +T P   IR
Sbjct: 4570 TDFRGLLQAFELLKQTREEESHRLEIELTEKAQKEDQEFEELVAFIQQRLTQTEPVTLIR 4629

Query: 1022 KLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
             +++  V   + AI E EI  N     + W +  + +    +KY  +  G    L I+N 
Sbjct: 4630 DIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLD-SSDKYKIKIEGDRHILKIKNC 4688

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRW 1139
             + D+G Y  +      +A +TV+E  P +   L +    +GN  T   + +  +A  +W
Sbjct: 4689 QLEDQGNYRIVCGPHIASARLTVIE--PAVERHLHDTTFKEGNTCTLSCQFSIPNAKSQW 4746

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199
            +++G  I+        +  K  KL I D   +D G+Y+C++ N + TA LT+E   I FT
Sbjct: 4747 YRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLDNLETTADLTIEAEPIQFT 4806

Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
              + + I+V  +  A    E+  +   VTWYK  + + ++ K++  S+ +   + I   T
Sbjct: 4807 KSI-QNIVVSEHQSATFECEVSFDDAVVTWYKGPTELTESPKYSFRSEGRCHYMTIHNVT 4865

Query: 1260 EDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292
             +D+  Y+ +       +A+ST +L +   E      PP + D
Sbjct: 4866 AEDEGVYSVIARLEPRGEARSTAELYLVTKEIKLELKPPDVPD 4908



 Score =  182 bits (443), Expect = 1e-43
 Identities = 228/1007 (22%), Positives = 389/1007 (38%), Gaps = 83/1007 (8%)

Query: 660  IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            I E DI   W  KGE + P     +  E         L +  VK  Q G     A+N   
Sbjct: 5657 ISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRF----LTLHKVKLEQAGEVLYQALN--- 5709

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             A    +L +K  E +      PLK + V +        + V      + W K    +K 
Sbjct: 5710 -AVTTAILTVKEIELD---FAVPLKDVTVPEKRQARF--ECVLTREANVIWSKGTDILKI 5763

Query: 778  ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
                   +DG  H I ++   +  DEG YT + E  +  A     + VE    +      
Sbjct: 5764 GEKFDIIADGKKH-ILVINDSQFDDEGEYTAEVEGKKSTAR----LFVEGVRLK------ 5812

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            FI   Q+ TVKE  T      ++   +  + WY+N++ +  S T+    +G+  +L +  
Sbjct: 5813 FITPLQDQTVKEGETAYFQFELSHEGM-LVKWYKNDKRLHTSRTVFITSEGKVHKLEMRE 5871

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
            V  + D  + K V  +    ++      ++ +    VK LQ  Y   E   + L+C+ S 
Sbjct: 5872 VTLD-DISEIKAVVKDM---NTQANLKVLEADPYFTVK-LQ-DYSALEKDDITLQCELSK 5925

Query: 955  TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014
             V  KWY + +E+       I  +G             D GV +C     +T+  + V+ 
Sbjct: 5926 DVPVKWYKDGEELVASSRISIKTDGLRRILTIKKATEGDKGVYECSCGTDKTNCNIGVEP 5985

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
             + +  R L   EV   + A  E+EI+      +W+  GE + P   + +  + G    L
Sbjct: 5986 RLIKVERPLYGVEVFVGETARFEIEISEPDVHPIWKLKGETLTPSP-ECEIIEDGKKHIL 6044

Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
             +    +   GE S    +    A + V ELP   IT L + KV + ++A FE E+++  
Sbjct: 6045 ILHQGRLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP 6104

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
               RW K   EI      ++  DG K  L I     DD  +Y  E  + + +A L +E  
Sbjct: 6105 KTFRWLKGTQEITPDERFEIISDGTKHALIIKSVAFDDEAKYMFEAEDKRTSAKLIIEGI 6164

Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
             + F   L +       T A  TVE+  E + V W+K    +  ++  ++  D K  TL 
Sbjct: 6165 RLKFITPLKDVTKKERET-AVFTVELSHENIPVVWFKNDQRLHTSKVVSMTDDGKFHTLT 6223

Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
            I+  T DD  +     +   S  KL   V+E  P      ++Y      +V L  +    
Sbjct: 6224 IKDLTIDDTSQIRVEAMGKSSEAKL--TVLEGDPYFTGKLQDYTAVEKDEVILQCEISKA 6281

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
              P  +W+ + K I   K+     D K   L +KK    D G Y      +CG      N
Sbjct: 6282 DAP-VKWMKDGKPITPSKNVVIKADGKKRILILKKALKKDIGQYTC----DCGTDQTSAN 6336

Query: 1375 VTILDKPSPPGKP----NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
            + I D+     +P     ++E +++  +I   E    GN     + ++ + +  +    +
Sbjct: 6337 LNIEDRDIEIIRPLYSVEVIETETARFDIEISEEGVHGN-----WKLKGEPLTESPDCEI 6391

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
            K   K           + Y  R      VD   A+  +  +  +K   I    + +PLK+
Sbjct: 6392 KEEGKKHFL-------TLYNVRLDQAGGVDFQAANAKSGAHLRVKPRVI---GLLRPLKD 6441

Query: 1491 ITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY 1548
            +T    E     C   + G+P   V WY  GKKL       E                  
Sbjct: 6442 VTVTAGESATFDCELSYEGIP---VEWYLQGKKL-------EPSDKVVTRAEGRAHTLIL 6491

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL---VTAVIE---GIPPP 1602
            + +   D GEV  +     + +  + +    ++    + D+ +    TA++E        
Sbjct: 6492 RDVKLTDAGEVSLT-AKDFRTQANLFVKEPPVEFTKPLEDQTVEEEATAILECEVSRENA 6550

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
            +V W+KNG ++   K+Y+I ++ +   + I       +  YT +A +
Sbjct: 6551 KVKWFKNGEEIHKTKKYDIISEGRVRKLIIHGCTLDDAKTYTCDAKD 6597



 Score =  181 bits (441), Expect = 2e-43
 Identities = 190/781 (24%), Positives = 321/781 (41%), Gaps = 54/781 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+F++K K  Y   GS  +LEC++   P   ++W   G+EI   +     +  +    
Sbjct: 3651 MPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNT--- 3707

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            CS LK+  +++   GTY+  A N  G       L +    +EPP  ++  +   V  GE+
Sbjct: 3708 CS-LKVNGLQESDMGTYSCTATNVAGSDECSAFLSV----REPPSFVKKPEPFNVLSGEN 3762

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKKVK--DEGVYTLKA 807
            +  ++ V G+P   + W + +  ++  P      T   S+  L+   V+    G YT + 
Sbjct: 3763 ITFTSIVKGSPPLEVKWFRGS--IELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQV 3820

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G    +  + V+EP +       F+ +  +++V++   + L    T  P  S+TW 
Sbjct: 3821 SNEAGKISCTTHLFVKEPAK-------FVMKVNDLSVEKGKNLILECTYTGTPPISVTWK 3873

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS-HGARVTIDVE 926
            +N  I+  SE  +      +  L I N   E D G Y C   N +G+ + HGA +TI +E
Sbjct: 3874 KNGVILKHSEKCSITTTETSAILEIPNSKLE-DQGQYSCHIENDSGQDNCHGA-ITI-LE 3930

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
               FV  L+   +   G +  L+CQ + T  +   WY    ++ G    ++  + +    
Sbjct: 3931 PPYFVTPLE-PVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFKNQVATL 3989

Query: 985  XXXXXXXXDVGVIKCIVK----DQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEV 1038
                    D G   C V+    +  +S++L V+E    P F RKL+D           + 
Sbjct: 3990 VFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDC 4049

Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
             I  SE  +V W +D   +K   N +      ++  L I  T     G+Y+C   +   T
Sbjct: 4050 GIAGSEPIEVSWFKDNVRVKEDYNVHT-SFIDNVAILQILKTDKSLMGQYTCTASNAIGT 4108

Query: 1098 AE------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
            A       +T  + PP   T +       G  A FE  ++    + V W KD  EI+   
Sbjct: 4109 ASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIRVTWAKDNQEIRTGG 4168

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLPE 1204
            + Q++       L I   D  D+G+Y+C    EVG   CTA L V+E      FT +L E
Sbjct: 4169 NYQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVKERKTPPTFTRKLSE 4228

Query: 1205 FILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             +      +  L   +   + L V+WYK    +  +    +        L I+   + D 
Sbjct: 4229 AVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDA 4288

Query: 1264 CEYTC-VLLDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQP-ND 1319
              YTC V  +A S       V+  P  P + D   +       D   L  +    +P   
Sbjct: 4289 GLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRI 4348

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +W+   + I+  +    S  +  A L +  V  +D+G Y  +  N  G       VT+ +
Sbjct: 4349 QWLKAGREIRASERCSFSFANGVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKE 4408

Query: 1380 K 1380
            K
Sbjct: 4409 K 4409



 Score =  178 bits (434), Expect = 1e-42
 Identities = 241/1074 (22%), Positives = 432/1074 (40%), Gaps = 81/1074 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P   ++ ++Q V +G+D     R+V  P+P+  W   G +I   + I      D    C 
Sbjct: 1805 PKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWYWPEDN--VCE 1862

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            ++ I +V      +  V AVN  GE S    L ++   K+    I+ L+ ++ ++ +S+ 
Sbjct: 1863 LV-IRDVTADDSASIMVKAVNIAGETSSHAFLLVQA--KQLISFIQNLQDVVAKERDSMA 1919

Query: 754  LSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
                    P   + W KN   + +       SD   H +++L  + + D   Y+      
Sbjct: 1920 TFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVE-MSDADDYSCALVED 1978

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            E + +T+A + VE    E      FI   +++ V E  T +L   V+   +    WY  +
Sbjct: 1979 ESV-KTTAKLIVEGAVVE------FIKELEDVEVPESFTGELECEVSPEDIEG-KWYHGD 2030

Query: 871  -EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             E+ S  + +  +  G  I L I +V+ + D G+Y  V     GK +H  ++ +    +T
Sbjct: 2031 VELSSNHKYVLASRRGRRI-LTIKDVNKD-DQGEYSFVVD---GKRTH-CKLKMKPRPMT 2084

Query: 930  FVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
             ++ L    +  EG  V LE + S   V   W  +  EI   D   I+ + +        
Sbjct: 2085 ILQGLTDQ-KVCEGDIVQLEVKVSVENVEGVWMKDGHEIQSSDRIHIVLDKQSHMLLIED 2143

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047
                D G     +   E ST   V     E I  L+D  V E   AILE ++++ +    
Sbjct: 2144 ATQEDSGTYSFSIPGLELSTTGQVTVYSVEIIVPLKDVHVVEGTKAILECKVSAPDVTSS 2203

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W  +   IKP + +     +G  ++L I  T   DEG Y  ++     +  VTV E+  
Sbjct: 2204 KWYLNDHQIKPDE-RVQAVCKGTKQRLVITRTHASDEGHYKLMVGKVETSCNVTVEEI-- 2260

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
            EII  L +    +    +FE+EL+     V W   G EI+     ++   GK  KL +  
Sbjct: 2261 EIIRGLHDITCTETQNVSFEVELSHSGIDVIWHFKGQEIKAGPKYKIEARGKIYKLTVVK 2320

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
               DD GEY    G  K +  L V   +I+  L     + V  +  A    E+ +   + 
Sbjct: 2321 MMKDDEGEYVFYAGGKKTSGKLIVAGGAISKPL---ADLTVAESQRAVFECEVANPESEG 2377

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287
             W K    +  T+++   +D  KR L I     DD  EY+  +  +K++ KL VE V   
Sbjct: 2378 QWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEYSYEIASSKTSAKLHVEAV--- 2434

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
             KI    +   +    +    V+          WI N   ++     + S+     +L I
Sbjct: 2435 -KIKKTLKNLTVTETQEAVFSVELSHPDVKGALWIKNGVELESNDKYEISVKGTVHTLKI 2493

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            K    TD  +Y  +L     +A + +  V I+ KP      ++  ++++ ++       +
Sbjct: 2494 KHCVVTDESVYSFKLGKIGANARLHVETVKIIKKPK-----DVTALENAVVSFELSVSHD 2548

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            T      +  VE ++ D  + IS + + K    + N+    +  + A+ V +++      
Sbjct: 2549 TVPVRWFHKNVELKQSDKYKMISQRKVHKLM--LHNISPADAGEYTAF-VGQLECK---- 2601

Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA- 1525
                 K+  ET      + K +K+I     +     C       P V W ++G +++ + 
Sbjct: 2602 ----AKLFVET----IHITKTMKSIEIPETKTASFQCEVSHFNVPSV-WLKNGVEIEMSE 2652

Query: 1526 --KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIK 1581
              K   + +                Y  +  ND   V  +  V    KP+ IT   EDI 
Sbjct: 2653 KFKIVVQGKLHQLNIMNTSSEDSAEYTFVCGND--RVSATLTV----KPILITSMLEDIN 2706

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
             + K    + VT   EGI      W KNG ++++  +  I TK+ T  + I+ +    ++
Sbjct: 2707 AEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQIRTKKLTHSLSIRNVHFGDAA 2763

Query: 1642 KYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEW 1687
            +Y+  A   A ++++ V  +  +        K  + +  +   EIS   V ++W
Sbjct: 2764 EYSFVAGKAASSATLYVEARHIEFRKHIKDIKVVEKKRAIFECEISEPDVQVQW 2817



 Score =  177 bits (432), Expect = 2e-42
 Identities = 224/998 (22%), Positives = 415/998 (41%), Gaps = 69/998 (6%)

Query: 695  LKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751
            L I +V+    G YT V    N+E  ++  +++     E+ P + ++ L+  + V +G+ 
Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIV-----EELPVRFVKTLEEEVTVVKGQP 5467

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLKA 807
            + L+ ++  N   ++ W ++ K +K  P K      G +HS+TI       D G YT+  
Sbjct: 5468 LYLTCEL--NKERSVVWRRDGKIIKDKPGKFALGIIGLSHSLTITDSDD-SDAGTYTVTV 5524

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            E+SE ++ +S V  VE   +   +P       ++  VK KGT      + ++  P+I W+
Sbjct: 5525 EDSE-LSCSSCVKVVEVIRDWLVKP------IRDQHVKPKGTATFTCDIVKD-TPNIKWF 5576

Query: 868  RNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            + +E I   P++      +G  I L I N     D G+Y            + A++T+  
Sbjct: 5577 KGDEEIPAEPTDKTEILKEGNKIFLKIKNA-GPADIGEYSVEVEGRR----YPAKLTLGE 5631

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
             +V  +K L+      E +T   + + S   +  +W    + +      EI  EG     
Sbjct: 5632 REVELLKPLE-DVTVYEKETANFDTEISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRFL 5690

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                      G +     +  T+ +L VKE   +F   L+D  V EK  A  E  +  E 
Sbjct: 5691 TLHKVKLEQAGEVLYQALNAVTTAILTVKEIELDFAVPLKDVTVPEKRQARFECVLTRE- 5749

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A+V+W +  +I+K  + K+D    G    L I ++   DEGEY+  +  +  TA + V  
Sbjct: 5750 ANVIWSKGTDILKIGE-KFDIIADGKKHILVINDSQFDDEGEYTAEVEGKKSTARLFVEG 5808

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            +  + IT LQ+Q V +G  A F+ EL+    LV+W+K+   +  S  + +T +GK  KL+
Sbjct: 5809 VRLKFITPLQDQTVKEGETAYFQFELSHEGMLVKWYKNDKRLHTSRTVFITSEGKVHKLE 5868

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            + +  LDD  E    V +    A L V E    FT++L ++  +  + D  L  E+  + 
Sbjct: 5869 MREVTLDDISEIKAVVKDMNTQANLKVLEADPYFTVKLQDYSALEKD-DITLQCEL-SKD 5926

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            + V WYK    +  + + ++ +D  +R L I+K TE D+  Y C     K+   + VE  
Sbjct: 5927 VPVKWYKDGEELVASSRISIKTDGLRRILTIKKATEGDKGVYECSCGTDKTNCNIGVE-- 5984

Query: 1285 EFPPKIVDYERE-YRIKRGSDVTLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
               P+++  ER  Y ++     T   + + + P  +  W +  + +      +   D K 
Sbjct: 5985 ---PRLIKVERPLYGVEVFVGETARFEIEISEPDVHPIWKLKGETLTPSPECEIIEDGKK 6041

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L + +      G    +  N    A++++    L   +P     + E D +       
Sbjct: 6042 HILILHQGRLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKF----- 6096

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
            E E +       ++   QEI   E    + + TK    I+++  +   ++   A      
Sbjct: 6097 ECEVSREPKTFRWLKGTQEITPDERFEIISDGTKHALIIKSVAFDDEAKYMFEA------ 6150

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
                + T    +I+  +++  T   PLK++T +  E    T        P V W+++ ++
Sbjct: 6151 --EDKRTSAKLIIEGIRLKFIT---PLKDVTKKERETAVFTVELSHENIP-VVWFKNDQR 6204

Query: 1522 LKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
            L T+K  +  +                   I     G+   + +  ++  P  T   +D 
Sbjct: 6205 LHTSKVVSMTDDGKFHTLTIKDLTIDDTSQIRVEAMGKSSEAKLTVLEGDPYFTGKLQDY 6264

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
                K  DE ++   I     P V W K+G  +   K   I    K  ++ +K+  +   
Sbjct: 6265 TAVEK--DEVILQCEISKADAP-VKWMKDGKPITPSKNVVIKADGKKRILILKKALKKDI 6321

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
             +YT +     GT      L + D+  +   P+   E+
Sbjct: 6322 GQYTCD----CGTDQTSANLNIEDRDIEIIRPLYSVEV 6355



 Score =  176 bits (429), Expect = 5e-42
 Identities = 219/964 (22%), Positives = 386/964 (40%), Gaps = 66/964 (6%)

Query: 712  AVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
            A+  EG+ ++P     K   +   E P++ E ++S  V QG       +VVG P P   W
Sbjct: 1779 ALPPEGKITIPTFKPEKVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQW 1838

Query: 769  CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
             +N   ++    +      D     +++     D     +KA N  G   + A + V+  
Sbjct: 1839 FRNGVQIERTDRIYWYWPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQA- 1897

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
                 +   FI   Q++  KE+ ++      T  P   + W++N   I   E    + D 
Sbjct: 1898 ----KQLISFIQNLQDVVAKERDSMATFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDR 1953

Query: 886  ENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
            +   L +  V+   D+ DY C +  + + K++  A++ ++   V F+K L+   E  E  
Sbjct: 1954 KAHFLSVLAVEMS-DADDYSCALVEDESVKTT--AKLIVEGAVVEFIKELE-DVEVPESF 2009

Query: 945  TVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGR-XXXXXXXXXXXXDVGVIKCIVK 1002
            T  LEC+ S   +  KWYH   E+S  +H+ ++   R             D G    +V 
Sbjct: 2010 TGELECEVSPEDIEGKWYHGDVELSS-NHKYVLASRRGRRILTIKDVNKDDQGEYSFVVD 2068

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG-EIIKPKKN 1061
             + T   L +K      ++ L D +V E D+  LEV+++ E  + VW +DG EI    + 
Sbjct: 2069 GKRTHCKLKMKPRPMTILQGLTDQKVCEGDIVQLEVKVSVENVEGVWMKDGHEIQSSDRI 2128

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCIL--RDESCTAEVTVVELPPEIITRLQNQKVN 1119
                +K+ H+  L I + +  D G YS  +   + S T +VTV  +  EII  L++  V 
Sbjct: 2129 HIVLDKQSHM--LLIEDATQEDSGTYSFSIPGLELSTTGQVTVYSV--EIIVPLKDVHVV 2184

Query: 1120 KGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            +G KA  E +++  D    +W+ +  +I+    +Q    G KQ+L I      D G Y  
Sbjct: 2185 EGTKAILECKVSAPDVTSSKWYLNDHQIKPDERVQAVCKGTKQRLVITRTHASDEGHYKL 2244

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
             VG  + +  +TVEE  I   +R    I      +    VE+    +DV W+ K   I+ 
Sbjct: 2245 MVGKVETSCNVTVEEIEI---IRGLHDITCTETQNVSFEVELSHSGIDVIWHFKGQEIKA 2301

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298
              K+ + +  K   L + K  +DD+ EY       K++ KL V        + D      
Sbjct: 2302 GPKYKIEARGKIYKLTVVKMMKDDEGEYVFYAGGKKTSGKLIVAGGAISKPLADL----- 2356

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
                S   +     A P+   +W+ N K +      +   D     L I   +  D G Y
Sbjct: 2357 TVAESQRAVFECEVANPESEGQWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEY 2416

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
               + ++   A + +    + K        + E   +  ++    P+  G +  I   VE
Sbjct: 2417 SYEIASSKTSAKLHVEAVKIKKTLK--NLTVTETQEAVFSVELSHPDVKG-ALWIKNGVE 2473

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSS-YRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +  D  E ISVK    T      + T+ S Y F+   +     ++A    E  K+IK+ 
Sbjct: 2474 LESNDKYE-ISVKGTVHTLKIKHCVVTDESVYSFKLGKIG----ANARLHVETVKIIKK- 2527

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXX 1535
                P     L+N         EL+     VP   V W+    +LK +        R   
Sbjct: 2528 ----PKDVTALENAVV----SFELSVSHDTVP---VRWFHKNVELKQSDKYKMISQRKVH 2576

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTA 1594
                         +  AF   G++E    + ++   +  T+ + +I +      +  V+ 
Sbjct: 2577 KLMLHNISPADAGEYTAF--VGQLECKAKLFVETIHITKTMKSIEIPETKTASFQCEVSH 2634

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
                +P    +W KNG ++E  +++ I  + K   + I       S++YT    N   ++
Sbjct: 2635 F--NVPS---VWLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSSEDSAEYTFVCGNDRVSA 2689

Query: 1655 SVEV 1658
            ++ V
Sbjct: 2690 TLTV 2693



 Score =  173 bits (420), Expect = 6e-41
 Identities = 257/1174 (21%), Positives = 453/1174 (38%), Gaps = 112/1174 (9%)

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            KKPK     E + +  E  +     P + W  K  E+   +   +  +  +H     L +
Sbjct: 2526 KKPKDVTALENAVVSFELSVSHDTVP-VRWFHKNVELKQSDKYKMISQRKVHK----LML 2580

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
             N+     G YT      E +A L +         E   + + +KS+ + + ++     +
Sbjct: 2581 HNISPADAGEYTAFVGQLECKAKLFV---------ETIHITKTMKSIEIPETKTASFQCE 2631

Query: 758  VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            V     P++ W KN   ++          G  H + I+     +D   YT    N     
Sbjct: 2632 VSHFNVPSV-WLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSS-EDSAEYTFVCGNDR--- 2686

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
              SA +TV+        P L  +  ++I  +EK TI     V    + S  W +N   I 
Sbjct: 2687 -VSATLTVK--------PILITSMLEDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIK 2736

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             ++            L I NV    D+ +Y  VA    GK++  A + ++   + F KH+
Sbjct: 2737 STDKCQIRTKKLTHSLSIRNVHFG-DAAEYSFVA----GKAASSATLYVEARHIEFRKHI 2791

Query: 935  QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
             K  +  E K  I EC+ S   V  +W  + +E+   D  +I +E              D
Sbjct: 2792 -KDIKVVEKKRAIFECEISEPDVQVQWMKDGQELQIGDRMKIQREKYVHRLIIPSTKMSD 2850

Query: 994  VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
             G    +     +S  L+V+          ++ +V E+  A +E E+N +  +  W +DG
Sbjct: 2851 AGQYTVVAGGNTSSANLIVEGRDVRIRSIRKEIQVIERQRAEIEFEVNEDDIEPQWYKDG 2910

Query: 1054 -EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPEIIT 1111
             EI    + +Y +     I ++ I  T+  D GEY+ +  R+ S          PP+II 
Sbjct: 2911 IEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGRNRSSVVLYVNAPEPPQIIQ 2970

Query: 1112 RLQNQKVNKGNKATF-EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
             LQ   V  G  A F  I   K    V W+KD  ++      +   D ++  L + +   
Sbjct: 2971 ELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETFP 3030

Query: 1171 DDAGEYSCEVGN----SKCTAILTVEEPSI-NFTLRLPEF---ILVPANT-------DAY 1215
            +D+  Y+CE  N    +  +A L+VE P + +  L +P +   ++VP           A 
Sbjct: 3031 EDSAVYTCEAKNDYGVATTSASLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSAR 3090

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-K 1274
                +    L V+WY K   I+ +  F +        L I +   +D+  YT V  ++  
Sbjct: 3091 FQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSVG 3150

Query: 1275 STTKLKVEVVEFPPKIV------DYEREYRI-----KRGSDVTLLVDY--------QAFP 1315
              T   +  +E P KI+      + E E ++     +R   + + V++        +  P
Sbjct: 3151 QVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTP 3210

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
                +W    + I           +  ++L I + +  D G Y  +  N  G       +
Sbjct: 3211 NVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFL 3270

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPE---NTGNS---TIIYYVVEYQEIDTTEWIS 1429
            T+ + P       I ++DSS +    D        G S    + +Y  E  EI  +E  S
Sbjct: 3271 TVTEPPR-----FIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGE-TEIHPSEKYS 3324

Query: 1430 VKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
            +  +       + NL    S  +   A N      AS +T       + K      +KP 
Sbjct: 3325 MSFVDSVAVLEMHNLSVEDSGDYSCEAQNPA--GSASTSTSL-----KVKAPPAFTKKP- 3376

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYEN-RXXXXXXXXXXXX 1544
              + T    D+ L C   G P  +++WY+D ++++++   K   EN              
Sbjct: 3377 HPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSENYLASIHILNVDTAD 3436

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y C A ND G    SC+  +  +   T   +       VG+   + A +EG  P  V
Sbjct: 3437 VGEYHCKAVNDVG--SDSCIGSVTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISV 3494

Query: 1605 IWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            +W K+ G  +   +   I+  E  + ++I   + +++ KY  +  N AG       L V 
Sbjct: 3495 LWLKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVL 3554

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWIKVADVDRD 1722
            +     E P  ++  + +S T+E      DG  ELT ++  + +E   +   K++  ++ 
Sbjct: 3555 EPAVIVEKPGPVKVTAGDSCTLECTV---DGTPELTARWFKDGNELSTDHKYKISFFNKV 3611

Query: 1723 VETYCIQK-LNENCEYMFRVIAQNPVGFSEALES 1755
                 +   L ++ EY F V  +N VG S    S
Sbjct: 3612 SGLKILNAGLEDSGEYTFEV--KNSVGKSSCTAS 3643



 Score =  159 bits (386), Expect = 8e-37
 Identities = 220/917 (23%), Positives = 364/917 (39%), Gaps = 105/917 (11%)

Query: 414  PVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQY 473
            PV+V  GD+  ++   VA T E I        Y  DT  +    V+ H   +   +    
Sbjct: 3940 PVQVTVGDSA-SLQCQVAGTPEMI-----VSWYKGDTKLRGTATVKMHFKNQVATLVFSQ 3993

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            + D ++  +Y+ K  N  + +       T +E+ + P F  KLR  H   G  V F+C +
Sbjct: 3994 V-DSDDSGEYICKVENT-VGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGI 4051

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G                 S+  ++ +  DNV          ED    T    N A    
Sbjct: 4052 AG-----------------SEPIEVSWFKDNVRV-------KEDYNVHTSFIDNVAILQI 4087

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY---VDEGSD 650
              T+  +    +      T               + EG  P F   P       + E +D
Sbjct: 4088 LKTDKSLMGQYT-----CTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESAD 4142

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKFQEGTYT 709
               EC +       + W    +EI    N  ++ +E+  H     L I  V +   G YT
Sbjct: 4143 F--ECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAH-----LTILRVDRGDSGKYT 4195

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITW 768
              A N  G+ S    L +K   K PP     L   +   +G  + L  +V G+   T++W
Sbjct: 4196 CYASNEVGKDSCTAQLNVKE-RKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSW 4254

Query: 769  CKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPT 826
             KNN+ V + P       ++  +L  K V   D G+YT K  N  G    ++ + + EP 
Sbjct: 4255 YKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREP- 4313

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                +PP+F    Q    +E  T++L   V  +    I W +    I  SE  + +F   
Sbjct: 4314 ---KKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSF-AN 4369

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------------DVE-KVTFVK 932
             + L+     ++ DSG+Y C ASN AG  +  ++VT+             D+E K+ FV 
Sbjct: 4370 GVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVS 4429

Query: 933  HLQKSYETEEG-KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXX 990
              Q     E+   T I +       + KW   K        R IIQ+ G           
Sbjct: 4430 EPQSIKVMEKTVATFIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTT 4489

Query: 991  XXDVGVIKCIVKDQ----ETSTMLVV----KETIPEFIR-KLQDFEVKEKD-----VAIL 1036
              D G+ KC+  +Q    E S  L V    +E + E +R KL+    K+K+     + IL
Sbjct: 4490 KTDSGLYKCVAFNQHGEIERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDIL 4549

Query: 1037 EVEINSETADV--------VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            E+  N +  +         + +  G +   +  K   E+  H  ++ +   +  ++ E+ 
Sbjct: 4550 ELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQTREEESHRLEIELTEKAQKEDQEFE 4609

Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF--EIELTKGDALVRWFKDGSEI 1146
             ++        +T  E P  +I  ++NQ V     A F  EI++   +  + W+K   ++
Sbjct: 4610 ELV--AFIQQRLTQTE-PVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKL 4666

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI 1206
              S+  ++ I+G +  LKI +C L+D G Y    G    +A LTV EP++     L +  
Sbjct: 4667 DSSDKYKIKIEGDRHILKIKNCQLEDQGNYRIVCGPHIASARLTVIEPAVE--RHLHDTT 4724

Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCE 1265
                NT   L+ +         WY+    I+   ++ T +SD K   LII+    +DQ +
Sbjct: 4725 FKEGNT-CTLSCQFSIPNAKSQWYRNGRPIKIGGRYSTQVSD-KVHKLIIKDVRTEDQGQ 4782

Query: 1266 YTCVLLDAKSTTKLKVE 1282
            YTC L + ++T  L +E
Sbjct: 4783 YTCKLDNLETTADLTIE 4799



 Score =  135 bits (327), Expect = 1e-29
 Identities = 136/611 (22%), Positives = 249/611 (40%), Gaps = 34/611 (5%)

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V++ P +  RL+  +V   + A F  E+ T  +   +W+K G EI   +   +       
Sbjct: 3179 VKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLS 3238

Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
             L+I    + D GEYSC+  N       TA LTV EP   F  +L    LV  +      
Sbjct: 3239 TLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTVTEPP-RFIKKLDSSRLVKQHDSTRYE 3297

Query: 1218 VEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD---- 1272
             ++     + VTWYK ++ I  +EK+++        L +   + +D  +Y+C   +    
Sbjct: 3298 CKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVLEMHNLSVEDSGDYSCEAQNPAGS 3357

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            A ++T LKV+    PP         +  +GSDV L  + Q  P     W  + + I+  K
Sbjct: 3358 ASTSTSLKVKA---PPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSK 3414

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
              K   ++  AS+ I  V+  D G Y  +  N+ G      +VT+   P+   K + + +
Sbjct: 3415 KYKVMSENYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSDVTV 3474

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITKTQTSIQNLKTNSSYR 1450
                        E     ++++   + + I  +E  WIS          I N +  ++ +
Sbjct: 3475 VVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSE-NVASLKIGNAEPTNAGK 3533

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +     N+       E      V++   I    VEKP   +     +   L C   G P+
Sbjct: 3534 YICQIKNDAGFQ---ECFAKLTVLEPAVI----VEKP-GPVKVTAGDSCTLECTVDGTPE 3585

Query: 1511 PKVTWYRDGKKLKTA---KATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVG 1566
                W++DG +L T    K ++ N+                Y     N  G+   +  + 
Sbjct: 3586 LTARWFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQ 3645

Query: 1567 IQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
            +  + +       +K+ + ++G   ++   + G PP  V W+ +G ++ +  +Y  T  +
Sbjct: 3646 VSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTD 3705

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT- 1684
             T  +++  L+ S    Y+  A+N AG+      L V + PS  + P     +S E++T 
Sbjct: 3706 NTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFVKKPEPFNVLSGENITF 3765

Query: 1685 ---IEWKPPLD 1692
               ++  PPL+
Sbjct: 3766 TSIVKGSPPLE 3776



 Score =  129 bits (312), Expect = 7e-28
 Identities = 107/433 (24%), Positives = 176/433 (40%), Gaps = 26/433 (6%)

Query: 1643 YTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLE 1697
            + + A N  G    S     +K+ D   +P G + +   + ++ SV + W+PPL+DGG  
Sbjct: 7500 FRVRAQNMVGVGKPSHPTRAVKITDPIERPSGNINLDHSDQTKTSVQLTWEPPLEDGGSP 7559

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757
            +  Y IE+ E   ++WI+          + +  L     Y +RV A+N  G S+  E+  
Sbjct: 7560 ILGYIIERKEEGTDKWIRCNPKLVPACAFKVTGLKAGSSYYYRVSAENAAGVSDPAEA-- 7617

Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXX 1817
             +     D P            D   V +   P       PI  Y +        W    
Sbjct: 7618 -IGPLTADDPFVDLQWPLSAFKDGLEVIV---PEPIKIRVPITGYPIPTAT----WSFGD 7669

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSL-------PYTSDDKITIGKTLTPPSQPR 1870
                   R+   + +T  +  I         +       P +S         L  PS P+
Sbjct: 7670 QVLEEGGRVTMKTTSTFAELVITPSERPDKGIYTLTLENPVSSVSGEIDVNVLARPSAPK 7729

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
               V + +  +V L W  PE +GGSP+ +YIIE + V  K+W K++       E  + ++
Sbjct: 7730 ELKVVDVSRSTVQLSWEPPEDDGGSPVIDYIIEKREVSRKTWIKVMD-HVIDQEFSVPDL 7788

Query: 1931 KEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
             +  E +FR+ A N  G   P    + + +   ATVP PP   ++ R   S  +  +W  
Sbjct: 7789 IQGKEYLFRVCACNKCGPGEPAYIDEPINMSAPATVPDPP-ENVKWRNPTSKGIFLTWEP 7847

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            P++DGGA + GY +         W   G+  + T K  +  L E   Y  R+ A N IG 
Sbjct: 7848 PKYDGGARIKGYLVEKCQRGTDKWEICGEPVIET-KMEVTKLKEGEWYAYRVKALNRIGA 7906

Query: 2050 SEPLESDEPFKVI 2062
            S+P +  +  + I
Sbjct: 7907 SKPSKPTDDIQAI 7919



 Score =  118 bits (284), Expect = 2e-24
 Identities = 114/469 (24%), Positives = 191/469 (40%), Gaps = 35/469 (7%)

Query: 484  LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
            L+K+   K+ +      P +E     P  V  L+ K   +G +V  EC + G+P+P +TW
Sbjct: 665  LRKESEAKVTETARVPVP-AEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTW 723

Query: 544  FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--------- 594
            +R+   I+ S DFQ+ +    +A LVIRE F ED+G FTC A N AG  S+         
Sbjct: 724  YREDYKIESSMDFQITFKA-GLARLVIREAFAEDSGRFTCTATNKAGSVSTSCHLHVKVS 782

Query: 595  ----TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL-EGIPPTFSKKPKAQYVDEGS 649
                T E I E  +++  S +               ++  E +PP F +KP    + EG 
Sbjct: 783  EETETRETISEKVVTEEKSYVETKDVVMEDVSAAAEEVSGEPVPPFFIRKPVVHKLIEGG 842

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
             I+ EC++   P+P + W   G  +       V+ + +    C  L+I+       G YT
Sbjct: 843  SIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETG-ECK-LEISMTFADDAGEYT 900

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
            +V  N+ GEAS  + L     E +    I+  + M+ +   +  +    V    P I++ 
Sbjct: 901  IVIRNKFGEASATVSL---LEEADYEAYIKSQQEMMYQTQVTAYVQEPKVAEVAPPISYG 957

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS--EGIAETSAVITVEEPTE 827
              +K  +             T++    V+DE  +    E    + I       T++E  E
Sbjct: 958  DFDKEYEKEQALIRKKMAKDTVMVRTFVEDEEFHISSFEERLIKEIELRIIKTTLDELLE 1017

Query: 828  ENAEPPL------------FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
            E+ E  +            F  R +     E   +    + T  P+P I WY++ + I  
Sbjct: 1018 EDGEEMMIDISESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRH 1077

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             E        +    +   V    D G Y   ASN  G +   A++ ++
Sbjct: 1078 GERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNMKGNAICSAKLYVE 1126



 Score =  114 bits (275), Expect = 2e-23
 Identities = 64/198 (32%), Positives = 99/198 (50%), Gaps = 4/198 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P   RN  V+E     V L W EPES+GGS I  Y++E + +K K+W  +VT      E+
Sbjct: 7327 PGPVRNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVERRDIKRKTWI-VVTDHAENCEY 7385

Query: 1926 CIENIKEKD-EIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIV 1983
             +  +++   E +FR+SA N VG   P E++  V  +    VP PP   +E+  V     
Sbjct: 7386 TVTGLQKGGVEYLFRVSARNRVGTGEPVETERPVEAKSKFEVPGPPQN-VEVTDVNRFGR 7444

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
              +W  PE+DGG+P+ GY I +R+     W        + L   + D+ EN  Y  R+ A
Sbjct: 7445 TLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVLTDVVENEEYFFRVRA 7504

Query: 2044 RNEIGLSEPLESDEPFKV 2061
            +N +G+ +P       K+
Sbjct: 7505 QNMVGVGKPSHPTRAVKI 7522



 Score =  101 bits (243), Expect = 2e-19
 Identities = 101/361 (27%), Positives = 168/361 (46%), Gaps = 35/361 (9%)

Query: 1018 EFIRKLQDFEVKEKDV----AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            +F+++++D  +KE +     AI EV I+  TA   W +DG  I+ +  K+ F   G  RK
Sbjct: 5354 KFVKEMKDIVLKEAESVGSSAIFEVLISPSTAITSWMKDGSNIR-ESPKHKFIADGKDRK 5412

Query: 1074 LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEI 1128
            L+I +  + D GEY+C+LR    +++ TA++ V ELP   +  L+ +  V KG       
Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTC 5472

Query: 1129 ELTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK--C 1185
            EL K  ++V W +DG  I+       L I G    L I D D  DAG Y+  V +S+  C
Sbjct: 5473 ELNKERSVV-WRRDGKIIKDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDSELSC 5531

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI--EDTEKFT 1243
            ++ + V E   ++ ++      V     A  T +I  +T ++ W+K    I  E T+K  
Sbjct: 5532 SSCVKVVEVIRDWLVKPIRDQHVKPKGTATFTCDIVKDTPNIKWFKGDEEIPAEPTDKTE 5591

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRG 1302
            ++ +  K  L I+     D  EY+           ++VE   +P K+   ERE   +K  
Sbjct: 5592 ILKEGNKIFLKIKNAGPADIGEYS-----------VEVEGRRYPAKLTLGEREVELLKPL 5640

Query: 1303 SDVTL----LVDYQAFPQPND---EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
             DVT+      ++       D   EW +  +I++     +   +     LT+ KV+   A
Sbjct: 5641 EDVTVYEKETANFDTEISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRFLTLHKVKLEQA 5700

Query: 1356 G 1356
            G
Sbjct: 5701 G 5701



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 78/251 (31%), Positives = 110/251 (43%), Gaps = 10/251 (3%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
            G+ A FE+ ++   A+  W KDGS I+ S   +   DGK +KL I D  L DAGEY+C  
Sbjct: 5371 GSSAIFEVLISPSTAITSWMKDGSNIRESPKHKFIADGKDRKLHIIDVQLSDAGEYTCVL 5430

Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
             +GN +   TA L VEE  + F   L E + V      YLT E+  E   V W +   +I
Sbjct: 5431 RLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTCELNKER-SVVWRRDGKII 5489

Query: 1237 EDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE-FPPKIVDYE 1294
            +D   KF L       +L I    + D   YT  + D++ +    V+VVE     +V   
Sbjct: 5490 KDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDSELSCSSCVKVVEVIRDWLVKPI 5549

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVEN 1352
            R+  +K     T   D      PN +W    + I      K  I  +     L IK    
Sbjct: 5550 RDQHVKPKGTATFTCDI-VKDTPNIKWFKGDEEIPAEPTDKTEILKEGNKIFLKIKNAGP 5608

Query: 1353 TDAGIYKLRLE 1363
             D G Y + +E
Sbjct: 5609 ADIGEYSVEVE 5619



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 49/133 (36%), Positives = 69/133 (51%), Gaps = 1/133 (0%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G +  + A I G P P++ W K    L  D    I T    S + I + KRS S  Y 
Sbjct: 7940 KAGTKIELPAKITGKPEPQITWTKAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYI 7999

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            IEA N++G ++  V + V DKP  P     + EI+ ES  + W PP DDGG ++T Y +E
Sbjct: 8000 IEAVNSSGRATAVVEVNVLDKPG-PPAAFDVSEITNESCLLTWNPPRDDGGSKITNYVLE 8058

Query: 1705 KHEPDNNRWIKVA 1717
            K   D+  W K++
Sbjct: 8059 KRATDSEIWHKLS 8071



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 59/201 (29%), Positives = 99/201 (49%), Gaps = 13/201 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTH 787
            +P  V++P  S+   QG++     +VVG P P   W  N + V       +  K DG T 
Sbjct: 1184 KPVFVLKPT-SVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDG-TQ 1241

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
            S+ I+ P   +D G + + A+N  G A  S  ++VE   +E+   P F+ R + ++VKE 
Sbjct: 1242 SLIIV-PAMPEDSGEWAVIAQNRAGKASVSVTLSVE--AKEDLVRPRFVERLRNVSVKEG 1298

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI--DSGDYK 905
              + +  + T NP P I W +N++II P +      +G      + N++S    D+  Y 
Sbjct: 1299 SRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAAL-NIESTARQDAAWYT 1357

Query: 906  CVASNSAGKSSHGARVTIDVE 926
              A N AG+ +   +V ++VE
Sbjct: 1358 ATAINKAGRDTTRCKVNVEVE 1378



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 60/225 (26%), Positives = 106/225 (47%), Gaps = 17/225 (7%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTK--SDGDTHSIT 790
           P   +PL+S++  +G +    A + G P P ++W ++ + + A  LP    S  D  +  
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKL 65

Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
           ++      + G YT++A N  G A ++A + V   T     PP F  R Q +T ++   +
Sbjct: 66  VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTA----PPNFSQRLQSMTARQGSQV 121

Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
           +L  RVT  P P + +YR+   I  S       +G+   L+I     E DSG Y   A+N
Sbjct: 122 RLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPE-DSGTYSVNATN 180

Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955
           + G+++  A + I  E        +++   ++ KT++   Q S T
Sbjct: 181 NVGRATSTAELLIQGE--------EEAVPAKKTKTIVSTAQISQT 217



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 55/204 (26%), Positives = 94/204 (46%), Gaps = 11/204 (5%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  KP +    +G     + ++V  P P+  W   G+++V D    + I+ D      
Sbjct: 1185 PVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKED---GTQ 1241

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752
             L I        G + V+A NR G+AS+ + L ++  E    P+ +E L+++ V++G  +
Sbjct: 1242 SLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRL 1301

Query: 753  ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAE 808
             ++ +  GNP P I W KN+    P K    + +G   +  + ++    +D   YT  A 
Sbjct: 1302 HMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAI 1361

Query: 809  NSEGIAETSAVITVEEPTEENAEP 832
            N  G   T   + VE    E+AEP
Sbjct: 1362 NKAGRDTTRCKVNVE---VEHAEP 1382



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 58/203 (28%), Positives = 98/203 (48%), Gaps = 11/203 (5%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
           PTF++  ++    EGS    E  +   P P+++W   G+ +       V I  SD     
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGR--- 62

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           + L I +V +   G YT+ A N  G+A+    L +  G   PP   + L+SM  RQG  V
Sbjct: 63  AKLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTA-PPNFSQRLQSMTARQGSQV 121

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  +V G P P + + ++   +++ P      +GD +S+ I+     +D G Y++ A N
Sbjct: 122 RLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSL-IIAEAYPEDSGTYSVNATN 180

Query: 810 SEGIAETSAVITVEEPTEENAEP 832
           + G A ++A + ++   EE A P
Sbjct: 181 NVGRATSTAELLIQ--GEEEAVP 201



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 31/245 (12%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E+   P+FV K        G T +F+ +V G P P+  WF     +      ++   +D 
Sbjct: 1180 ERLYKPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDG 1239

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              +L+I    PED+G +  +A+N AG AS +  L VEA                      
Sbjct: 1240 TQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEA---------------------- 1277

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
              D+   + P F ++ +   V EGS + +  +    P PDI WL   + IVP +   + I
Sbjct: 1278 KEDL---VRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRI 1334

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
            E       + L I +  +     YT  A+N+ G  +    + ++    EP    EP + +
Sbjct: 1335 EGTKG--AAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEP----EPERRL 1388

Query: 745  IVRQG 749
            I+ +G
Sbjct: 1389 IIPKG 1393



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 33/92 (35%), Positives = 56/92 (60%), Gaps = 1/92 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F ++L+      GS V+ + +V G P P + ++R    I+ S DFQ+  + D + +L+
Sbjct: 104 PNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGD-LYSLI 162

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           I E +PED+GT++  A N  G A+ST EL+++
Sbjct: 163 IAEAYPEDSGTYSVNATNNVGRATSTAELLIQ 194



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 14/255 (5%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P  PE  V  R  + + + + W+PP  DGG  +  Y +EK +   ++W ++   +  +ET
Sbjct: 7825 PDPPEN-VKWRNPTSKGIFLTWEPPKYDGGARIKGYLVEKCQRGTDKW-EICG-EPVIET 7881

Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
               + KL E   Y +RV A N +G S+  + ++ I    A + P           +  ++
Sbjct: 7882 KMEVTKLKEGEWYAYRVKALNRIGASKPSKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKA 7941

Query: 1784 VYITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
                  P++  G   P I + K E + +   +             I     + +  + I 
Sbjct: 7942 GTKIELPAKITGKPEPQITWTKAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYIIE 8001

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N  G +   T+  ++ +   L  P  P  F VSE T+ S  L W  P  +GGS ITNY
Sbjct: 8002 AVNSSGRA---TAVVEVNV---LDKPGPPAAFDVSEITNESCLLTWNPPRDDGGSKITNY 8055

Query: 1901 IIEFKTVKGKSWTKI 1915
            ++E +    + W K+
Sbjct: 8056 VLEKRATDSEIWHKL 8070



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 2/108 (1%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            SE +++   F  +L+   T +G+ V F C+  GYP P+I W++    I+  + + M    
Sbjct: 1028 SESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQ 1087

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APLSDHG 608
            D  A+L +  V PED G +T  A N  G A  + +L VE  AP +  G
Sbjct: 1088 DGSASLRLPVVLPEDEGIYTVFASNMKGNAICSAKLYVEPVAPTATPG 1135



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 4/111 (3%)

Query: 495  LPVFEKPTSEEQSM---APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
            +P F KP   E S    AP   E+++ +    G+   F  +V G P P+  WFR    I+
Sbjct: 1788 IPTF-KPEKVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIE 1846

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             +     Y+ +DNV  LVIR+V  +D+ +    A N AG  SS   L+V+A
Sbjct: 1847 RTDRIYWYWPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQA 1897



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS--QDFQMYYDDDNVA 566
           AP F + L+     +GS   FE  + G+P P+++W+R   ++  +     Q+ + D   A
Sbjct: 5   APTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGR-A 63

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            LVI  V   ++G +T  A N +G A+ST EL+V A
Sbjct: 64  KLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTA 99



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 6/152 (3%)

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
           +K + V+++ +  L+ E+   + ET+ V     P E    PP  +   +  TV E  ++ 
Sbjct: 653 IKGEAVREDHLL-LRKESEAKVTETARVPV---PAEIPVTPPTLVWGLKNKTVTEGESVT 708

Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
           L   ++ +P P++TWYR +  I  S      F      LVI    +E DSG + C A+N 
Sbjct: 709 LECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAE-DSGRFTCTATNK 767

Query: 912 AGKSSHGARVTIDVEKVTFVKH-LQKSYETEE 942
           AG  S    + + V + T  +  + +   TEE
Sbjct: 768 AGSVSTSCHLHVKVSEETETRETISEKVVTEE 799



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 9/185 (4%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNK-YDFEKRGHIRKL 1074
            P F + LQ     E   A  E  I+     +V W RDG+++                 KL
Sbjct: 6    PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKL 65

Query: 1075 YIRNTSVHDEGEYSCILRDES----CTAE--VTVVELPPEIITRLQNQKVNKGNKATFEI 1128
             I + +  + G Y+    + S     TAE  VT    PP    RLQ+    +G++   ++
Sbjct: 66   VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDV 125

Query: 1129 ELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             +T     +V++++DG EIQ S   Q+  +G    L I +   +D+G YS    N+   A
Sbjct: 126  RVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVGRA 185

Query: 1188 ILTVE 1192
              T E
Sbjct: 186  TSTAE 190



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 52/177 (29%), Positives = 80/177 (45%), Gaps = 9/177 (5%)

Query: 1196 INFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            + F   + + +L  A +    A   V I   T   +W K  S I ++ K   I+D K R 
Sbjct: 5353 LKFVKEMKDIVLKEAESVGSSAIFEVLISPSTAITSWMKDGSNIRESPKHKFIADGKDRK 5412

Query: 1253 LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLV 1309
            L I      D  EYTCVL   + + T+  K+ V E P + V   E E  + +G  + L  
Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTC 5472

Query: 1310 DYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
            +     + +  W  + KIIK K       I   S SLTI   +++DAG Y + +E++
Sbjct: 5473 ELNK--ERSVVWRRDGKIIKDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDS 5527



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 2/98 (2%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +++   P  V    P    +G T +F C+V GYP P++ W+  + +I+ S+ F++ Y  D
Sbjct: 1563 QKEKQKPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRKSKRFRLRY--D 1620

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             +  L I +    D G     A+N  GF     +L ++
Sbjct: 1621 GIHYLDIVDCKSYDTGEVKVTAENPEGFIEHKVKLEIQ 1658



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 39/191 (20%), Positives = 81/191 (42%), Gaps = 9/191 (4%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533
            ++PT  +PL+++               G P P+V+WYRDG+ L  A       +  + R 
Sbjct: 4    KAPTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRA 63

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592
                          Y   A N  G+  ++  + +         ++ ++    + G +  +
Sbjct: 64   KLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRL 123

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
               + GIP P V +Y++G ++++  ++ I  +     + I E     S  Y++ A+N  G
Sbjct: 124  DVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVG 183

Query: 1653 --TSSVEVTLK 1661
              TS+ E+ ++
Sbjct: 184  RATSTAELLIQ 194



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 6/127 (4%)

Query: 1462 SDASET-TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            S+A  T T    V  E  +  PT+   LKN T    E + L C   G PQP VTWYR+  
Sbjct: 669  SEAKVTETARVPVPAEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDY 728

Query: 1521 KLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            K++++   + T++                  + C A N  G V TSC + ++     T +
Sbjct: 729  KIESSMDFQITFKAGLARLVIREAFAEDSGRFTCTATNKAGSVSTSCHLHVKVSEE-TET 787

Query: 1577 NEDIKQK 1583
             E I +K
Sbjct: 788  RETISEK 794



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%)

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            + E  E +A   A+  V    +E  +P L +   +   V E  T +   RVT  P+P + 
Sbjct: 1543 RIEELERMAHEGALPAVAVDQKEKQKPELVLVP-EPARVLEGETARFRCRVTGYPLPKVN 1601

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            WY N+++I  S+     +DG +  L I +  S  D+G+ K  A N  G   H  ++ I
Sbjct: 1602 WYLNSQLIRKSKRFRLRYDGIHY-LDIVDCKS-YDTGEVKVTAENPEGFIEHKVKLEI 1657



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 75/338 (22%), Positives = 131/338 (38%), Gaps = 30/338 (8%)

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI--AETSAVITVEEPTE 827
            K  KPVK    K     H + I KP+    +  +T  AE  +     ET   + V    E
Sbjct: 602  KITKPVKPPQLKP----HEVKI-KPESAPPQFPFTEAAETYKAHYDVETKKEVDVSIKGE 656

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
               E  L + +  E  V E   + + A +   P P++ W   N+ ++  E++T       
Sbjct: 657  AVREDHLLLRKESEAKVTETARVPVPAEIPVTP-PTLVWGLKNKTVTEGESVTLECHISG 715

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
                      E    DYK        +SS   ++T        V  +++++  + G+   
Sbjct: 716  HPQPTVTWYRE----DYKI-------ESSMDFQITFKAGLARLV--IREAFAEDSGRFTC 762

Query: 948  LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007
                 + +VST  + + K     + RE I E +            DV     +++D   +
Sbjct: 763  TATNKAGSVSTSCHLHVKVSEETETRETISE-KVVTEEKSYVETKDV-----VMEDVSAA 816

Query: 1008 TMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSETAD-VVWERDG-EIIKPKKNKYD 1064
               V  E +P F IRK    ++ E    I E ++       V+W++ G  +    + K  
Sbjct: 817  AEEVSGEPVPPFFIRKPVVHKLIEGGSIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVS 876

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            +++     KL I  T   D GEY+ ++R++   A  TV
Sbjct: 877  YKRETGECKLEISMTFADDAGEYTIVIRNKFGEASATV 914



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TS 1628
            KPV  +    +K     G        + G P PE  W+ NG ++ ND  + I  KE  T 
Sbjct: 1184 KPVFVLKPTSVKCSQ--GQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQ 1241

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
             + I       S ++ + A N AG +SV VTL V  K
Sbjct: 1242 SLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAK 1278



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 1/100 (1%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD- 561
            ++E  + P FVE+LR     +GS +    +  G P P I W + + II P +  ++  + 
Sbjct: 1277 AKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEG 1336

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
                A L I     +DA  +T  A N AG  ++  ++ VE
Sbjct: 1337 TKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVE 1376



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 2/123 (1%)

Query: 481  TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540
            T  L+ +  EKI      E+    E  +API   +L P         +F C+VE  P  +
Sbjct: 3155 TAILKLEAPEKI-MYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVK 3213

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              W++    I     + +    + ++TL I      D G ++C A N  G  SST  L V
Sbjct: 3214 FQWYKAGREIYDGDKYSI-RSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTV 3272

Query: 601  EAP 603
              P
Sbjct: 3273 TEP 3275



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            +F + L      +  TV+  C++   P  ++TWF+    +     F+ Y  D     LVI
Sbjct: 6701 VFTKNLHDLEVNENETVRLICEISK-PNAEVTWFKGDEEVPDGGRFE-YISDGRKRILVI 6758

Query: 571  REVFPEDAGTFTC 583
            R   PEDAG +TC
Sbjct: 6759 RNAHPEDAGKYTC 6771



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+   +   I G P P V WY+   K+E+  ++ IT K   + + I+E     S ++T  
Sbjct: 704  GESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAEDSGRFTCT 763

Query: 1647 ASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWK 1688
            A+N AG+ S    L V   + ++    +  + ++ E   +E K
Sbjct: 764  ATNKAGSVSTSCHLHVKVSEETETRETISEKVVTEEKSYVETK 806



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 10/133 (7%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM----AP-IFVE-KLRPKHTPD-GSTV 527
            + E  +  Y  K LN      P   KPT + Q++    AP IF++ KL    T   G+ +
Sbjct: 7888 LKEGEWYAYRVKALNRIGASKP--SKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKAGTKI 7945

Query: 528  QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
            +   ++ G P PQITW +   +++P  D        N +T+ I +    D+GT+   A N
Sbjct: 7946 ELPAKITGKPEPQITWTKAEKLLRP-DDRITIETTPNHSTVTITDSKRSDSGTYIIEAVN 8004

Query: 588  AAGFASSTTELIV 600
            ++G A++  E+ V
Sbjct: 8005 SSGRATAVVEVNV 8017



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 9/158 (5%)

Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEV 1283
            W+   + V+ D     +I +   ++LII     +D  E+  +  +    A  +  L VE 
Sbjct: 1218 WFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEA 1277

Query: 1284 VE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             E    P+ V+  R   +K GS + + V     P P+  W+ NS II   K+ +  I+  
Sbjct: 1278 KEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGT 1337

Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              +A+L I+     DA  Y     N  G       V +
Sbjct: 1338 KGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNV 1375



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 45/195 (23%), Positives = 81/195 (41%), Gaps = 8/195 (4%)

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775
            E +LP V  +   EK+ P+++   +   V +GE+     +V G P P + W  N++ +  
Sbjct: 1553 EGALPAVA-VDQKEKQKPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRK 1611

Query: 776  -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
             K    + DG  H + I+  K   D G   + AEN EG  E    + +++  +  +    
Sbjct: 1612 SKRFRLRYDG-IHYLDIVDCKSY-DTGEVKVTAENPEGFIEHKVKLEIQQREDFRSVLRR 1669

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
                  E  V E G  KL+  V +   P+    +    +  +E IT     E  E + + 
Sbjct: 1670 APEPRHEPVVTEPG--KLLFEVQKIDKPAEATTKEVVKLKRAERITHEKLSEESEELRSK 1727

Query: 895  VDSEIDSGDYKCVAS 909
                 + G Y+ + +
Sbjct: 1728 FKRRTEEGYYEAITA 1742



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 15/165 (9%)

Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
            VK   +   EV+I  E+A   +    E  +  K  YD E +  +  + I+  +V ++   
Sbjct: 607  VKPPQLKPHEVKIKPESAPPQFPFT-EAAETYKAHYDVETKKEV-DVSIKGEAVRED--- 661

Query: 1088 SCILRDESC-----TAEVTV-VELP---PEIITRLQNQKVNKGNKATFEIELT-KGDALV 1137
              +LR ES      TA V V  E+P   P ++  L+N+ V +G   T E  ++      V
Sbjct: 662  HLLLRKESEAKVTETARVPVPAEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTV 721

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
             W+++  +I+ S   Q+T      +L I +   +D+G ++C   N
Sbjct: 722  TWYREDYKIESSMDFQITFKAGLARLVIREAFAEDSGRFTCTATN 766



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 53/278 (19%), Positives = 110/278 (39%), Gaps = 13/278 (4%)

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529
            KV     +++P + + +++ T     D        G P P+  W+R+G +++     Y  
Sbjct: 1795 KVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWY 1854

Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISN-EDIKQKH 1584
               +N                    A N  GE  +   + +Q K +I+ I N +D+  K 
Sbjct: 1855 WPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQAKQLISFIQNLQDVVAKE 1914

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            +  D           P  +V W+KNG ++ + ++Y + +  K   + +  ++ S +  Y+
Sbjct: 1915 R--DSMATFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDYS 1972

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWKPPLDDGGLELTKYAI 1703
                      SV+ T K+  + +  E    + ++   ES T E +  +    +E   Y  
Sbjct: 1973 CA---LVEDESVKTTAKLIVEGAVVEFIKELEDVEVPESFTGELECEVSPEDIEGKWYHG 2029

Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
            +     N++++  +   R + T      ++  EY F V
Sbjct: 2030 DVELSSNHKYVLASRRGRRILTIKDVNKDDQGEYSFVV 2067



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 6/122 (4%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A +S   +    +   +E   E    P+F+ +   +   +  T +   +V   P+P   W
Sbjct: 1159 ARSSPSCSPARRLDETDEGQLERLYKPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYW 1218

Query: 867  YRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            + N + +    T  I    DG    L+I     E DSG++  +A N AGK+S    VT+ 
Sbjct: 1219 FHNGQQVVNDYTHKIVIKEDGTQ-SLIIVPAMPE-DSGEWAVIAQNRAGKAS--VSVTLS 1274

Query: 925  VE 926
            VE
Sbjct: 1275 VE 1276



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 13/132 (9%)

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
            + GI+ K +  +  +D+ +K +    + V    E IP   V+W+KN  +L   K  ++T 
Sbjct: 6161 IEGIRLKFITPL--KDVTKKERETAVFTVELSHENIP---VVWFKNDQRLHTSKVVSMTD 6215

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV-------TLKVYDKPSKPEGPVIMR 1676
              K   + IK+L    +S+  +EA   +  + + V       T K+ D  +  +  VI++
Sbjct: 6216 DGKFHTLTIKDLTIDDTSQIRVEAMGKSSEAKLTVLEGDPYFTGKLQDYTAVEKDEVILQ 6275

Query: 1677 -EISRESVTIEW 1687
             EIS+    ++W
Sbjct: 6276 CEISKADAPVKW 6287



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 10/98 (10%)

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-----LPTKSDGDTH-SITILKP 794
            LK+    +G  V    +  G P P I W K+ K ++      +    DG     + ++ P
Sbjct: 1041 LKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLP 1100

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
            +   DEG+YT+ A N +G A  SA + V EP    A P
Sbjct: 1101 E---DEGIYTVFASNMKGNAICSAKLYV-EPVAPTATP 1134



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 3/73 (4%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            G P P++ WYK+G ++ + + Y++   ++ ++ +R+  +       YT+ ASN  G +  
Sbjct: 1060 GYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNMKGNAI- 1118

Query: 1657 EVTLKVYDKPSKP 1669
              + K+Y +P  P
Sbjct: 1119 -CSAKLYVEPVAP 1130



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 4/77 (5%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            A I G P PEV WY++G  L         I+  +  + + I  +  ++S +YTI+A+N +
Sbjct: 27   AHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGS 86

Query: 1652 G--TSSVEVTLKVYDKP 1666
            G  TS+ E+ +     P
Sbjct: 87   GQATSTAELLVTAGTAP 103



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 13/169 (7%)

Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
           L  K   +T +   +  K V +E  Y    E  + + E  +    EE + E   PP FI 
Sbjct: 777 LHVKVSEETETRETISEKVVTEEKSYV---ETKDVVMEDVSA-AAEEVSGEPV-PPFFIR 831

Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN----IELVIT 893
           +     + E G+I    +V  NP P + W +    ++       ++  E     +E+ +T
Sbjct: 832 KPVVHKLIEGGSIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETGECKLEISMT 891

Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK-SYETE 941
             D   D+G+Y  V  N  G++S    +  + +   ++K  Q+  Y+T+
Sbjct: 892 FAD---DAGEYTIVIRNKFGEASATVSLLEEADYEAYIKSQQEMMYQTQ 937



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 17/173 (9%)

Query: 958  TKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012
            T W+HN +++ +   H+ +I+E              D G    I +++      S  L V
Sbjct: 1216 TYWFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSV 1275

Query: 1013 --KETI--PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK-NKYDFE 1066
              KE +  P F+ +L++  VKE     + V+       D+VW ++ +II P K  +   E
Sbjct: 1276 EAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIE 1335

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCIL-----RDES-CTAEVTVVELPPEIITRL 1113
                   L I +T+  D   Y+        RD + C   V V    PE   RL
Sbjct: 1336 GTKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEPEPERRL 1388



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 16/50 (32%), Positives = 25/50 (50%)

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            I E++      +  LKN  T     +   C   G P PK+ WY+DGK+++
Sbjct: 1027 ISESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIR 1076



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 43/180 (23%), Positives = 71/180 (39%), Gaps = 7/180 (3%)

Query: 1226 DVTWYKKKSVIED-TEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLD----AKSTTKL 1279
            +V+WY+   V+   T     IS    R  L+I   TE +   YT    +    A ST +L
Sbjct: 36   EVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGSGQATSTAEL 95

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
             V     PP      +    ++GS V L V     P P  ++  +   I+     +   +
Sbjct: 96   LVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQE 155

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDSSSIN 1398
                SL I +    D+G Y +   NN G A     + I  ++ + P K     + ++ I+
Sbjct: 156  GDLYSLIIAEAYPEDSGTYSVNATNNVGRATSTAELLIQGEEEAVPAKKTKTIVSTAQIS 215



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 35/174 (20%), Positives = 67/174 (38%), Gaps = 10/174 (5%)

Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXX--XXXXYKCIAFNDHGEVET 1561
            G P P+  W+ +G+++    T K   +                   +  IA N  G+   
Sbjct: 1210 GRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASV 1269

Query: 1562 SCVVGIQQKPVITISN--EDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617
            S  + ++ K  +      E ++    K G    +     G P P+++W KN + +   K 
Sbjct: 1270 SVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKY 1329

Query: 1618 -EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
                I   +  + + I+   R  ++ YT  A N AG  +    + V  + ++PE
Sbjct: 1330 PRIRIEGTKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEPE 1383


>UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin -
            Caenorhabditis elegans
          Length = 6048

 Score =  318 bits (782), Expect = 8e-85
 Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%)

Query: 935  QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992
            +K+ + +  K    +C  S      +WY ++KEI SG    +I+ E              
Sbjct: 25   EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 84

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049
            D G   C      T   L V E   +  F+  L +  E+     A+L  ++N+  A +VW
Sbjct: 85   DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 144

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107
             R  + I+    ++  EK    R  L I+     D+ E++  I +D     +V V E   
Sbjct: 145  YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 204

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
              +  +++QKVN+ + AT E ++   DA V W+ DG  I       ++    +K++L I 
Sbjct: 205  TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 264

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
               ++D GEY C   + +  A L V+  +  F + L +  ++  + D  L  +  D    
Sbjct: 265  GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 322

Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              W++    I      KF   S     TL I K   ++   Y       + +  + V   
Sbjct: 323  GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 382

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338
            E  P +    ++   K G    + V +Q        P  + + N K I +   K  +  I
Sbjct: 383  EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 442

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
                A +  K  +  D G + L L N+ G A     + + DKP PP  P     + +  +
Sbjct: 443  KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 502

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
            ++ W  P+    + +  Y++E QE  +  W  V     T   +++LK +  Y+FR  A+N
Sbjct: 503  DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 562

Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508
            E  +SD    E+      Y    K   + +  V+K    +  EP E+     I G +   
Sbjct: 563  ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 622

Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
              + +  W++ G+        T K   E++                 C    DHG+    
Sbjct: 623  REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 675

Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
             +    +K     +   IK  + KVG+       I G P PE +W  NG  L+      +
Sbjct: 676  -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 734

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
            +++    +++I+   R+ S K+TI   N++G+     T+ V  +P+ P+GP+ + ++  +
Sbjct: 735  SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 794

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
              T+ W PP DDGG  LT Y +E  + DN  ++I+V  VD +  T  +  L     Y FR
Sbjct: 795  GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 854

Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            V A N  G SE L ++    IK   D P            D + + I W P  K+GG+PI
Sbjct: 855  VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 913

Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             +Y VE++  + K+WK         A I  L     YQFR+ A N+ G   P    +K  
Sbjct: 914  EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 973

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915
                  P     + + S +     T++W      GG PI     E K  KG    +    
Sbjct: 974  AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1027

Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
            +T+    +EH   CI +    D   +R++ +N+ G      + +V L++    PS P  P
Sbjct: 1028 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1082

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            LE+  V  + +  SW  P+ DGG P+  Y +   D     W+   K  V   K +I  L 
Sbjct: 1083 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1140

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            +  TY  R+ A N+ G S+ L +D+  K
Sbjct: 1141 KGQTYQFRVKAVNKEGASDALSTDKDTK 1168



 Score =  253 bits (619), Expect = 5e-65
 Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%)

Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            P ++D    +E ++K G D +L +     P P   W      ++     K + +      
Sbjct: 2158 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 2217

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
             +K+   +D G Y ++ EN  G    E+ VT+LD PS P  P ++  I     ++ W EP
Sbjct: 2218 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 2277

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
            E+ G + I +YV+E Q+  T  W +      T   + +L     Y+FR  AVN    SD 
Sbjct: 2278 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520
             E  E   + K+   ++     P      + + D++ T     GG P     V       
Sbjct: 2338 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577
                A                      ++  A N  GE    + S  +  + + +    N
Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456

Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634
             D  + Q+ K G        +EG P P++ W+ NG+ L +    +I    +  + +  K 
Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
              R+ S KY I A+N +G    EV + + D P  PEGP+  ++I++ESV ++W  PLDDG
Sbjct: 2517 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 2576

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
            G  +T Y +EK E D  RW+   +      +  + KL+E  EY FRV A N  G S  L 
Sbjct: 2577 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 2633

Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813
            S+  IV K   D P            D + V + W P   +GG+PI  Y VE K +   W
Sbjct: 2634 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 2692

Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
                        A    L+   TYQFR+ A N+ G   P      +        P     
Sbjct: 2693 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 2752

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
             ++         +K         +P+  +     T+   +   +     S   H    ++
Sbjct: 2753 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 2812

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
              D  +++I  EN  G      + +V       VP  P  PL+I  +       +W  P 
Sbjct: 2813 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 2866

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             +GG  +L Y +   D ++  W EVG     T K N   L     Y  R+ A N  G S+
Sbjct: 2867 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 2924

Query: 2052 PLESDEP 2058
            PLE++EP
Sbjct: 2925 PLEAEEP 2931



 Score =  251 bits (614), Expect = 2e-64
 Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            PKI+   R+ +IK G    L VD+   P P   W V                S + S+  
Sbjct: 3040 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3099

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
               +  D+G YKL+++N  G  +    V + D+PS P  P  + ++   S  + W  P++
Sbjct: 3100 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3159

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             G + I  YVVE ++  T  W+ V   +T T  ++  L     Y FR  A N    SD+ 
Sbjct: 3160 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 3219

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519
             T E   V+ +    +P   KP +  I    N+ I++        GG P       R D 
Sbjct: 3220 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 3275

Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571
            K  +  K                       Y+ +A N  G  + S          + + P
Sbjct: 3276 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 3335

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
               +  +  + + K G+  ++T      P P++ W K G K     E   TT  +T ++ 
Sbjct: 3336 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 3391

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            I   +RS S    I+A N  G +   + + V DKP  PE  +    +SR + T+ W  P 
Sbjct: 3392 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 3450

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            DDGG E+  Y IE  E  +  W KV  +      Y ++ L    +Y FR+ A+N VG S+
Sbjct: 3451 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 3509

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809
              +  P+VIK   D P            D   V + W P   +GGSPI+ Y VE   K+ 
Sbjct: 3510 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 3568

Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
            G  W              +  L  N TYQFR+ A N  G   P    + +T    +  P 
Sbjct: 3569 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 3628

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
             P    V + T  S  L W  P  +GG+PI  YI+E K +    WT+            +
Sbjct: 3629 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 3688

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
            +N+ EK+E  FR+ A N+ G   P++ S  V +E+    P
Sbjct: 3689 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 3728



 Score =  250 bits (612), Expect = 3e-64
 Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            IK G+DV   V  +  P P  EWI N K +   K    S D K+    ++      AG+Y
Sbjct: 1289 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 1347

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             L   N  G     + V +L KPS P G   +  +     ++ W  PE+ G + I +Y +
Sbjct: 1348 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 1407

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            E  ++ T  W+       T+T++ NL+    Y+FR  AVN+   SD   T     ++ + 
Sbjct: 1408 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 1465

Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533
              + P  V+KP      + + D+       GG P       +  K  + + A     ++ 
Sbjct: 1466 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 1525

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588
                          ++  A N  G  + S     VV   +     I  ED+     KVG 
Sbjct: 1526 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 1585

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
                   I+G P P+V W  NG  +   K   I  +   S   + +  R  S KYTI A+
Sbjct: 1586 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 1644

Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
            N  GT SV + +KV  KP+KP+GP+ + ++  +  T++WKPP DDGG  +  Y IEK   
Sbjct: 1645 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 1704

Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766
             +  W+      R  +T + +  LN+   Y FRV A N  G S+ LE+E  I+ K   D 
Sbjct: 1705 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 1761

Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824
            P            D++ V + W P   +GG+PI +Y++E + +  +W+           A
Sbjct: 1762 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 1820

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
             +  L+ N  Y+FR+ A N+ G S P  +   +        P   R+ + + +     ++
Sbjct: 1821 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 1880

Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
             +  P S   +P +T +  + + ++     K+        +  ++ ++  D   F I A 
Sbjct: 1881 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 1939

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            N  G    T   +V ++K    P+ P  PL++  V  + V  +W  P+ DGG P+  Y I
Sbjct: 1940 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 1994

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
               D     W+   KV  +     +  L   H Y  R+ A N  G S+PLE+
Sbjct: 1995 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2046



 Score =  243 bits (595), Expect = 4e-62
 Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%)

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356
            R+K G  +   V+ +  P P  EW +N   +    +T    ++  +  LT K     D+G
Sbjct: 2464 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 2523

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
             YK+   N  G  + E++V ILD P  P  P    +I   S+ + WDEP + G S I  Y
Sbjct: 2524 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 2583

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            VVE QE D   W+     + T   +  L     Y+FR  AVN    S  +  T  + ++ 
Sbjct: 2584 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 2640

Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529
            +     P     +  +  + +  D+E       GG P    +   +D  G  ++ A+   
Sbjct: 2641 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 2700

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584
            +                 ++  A N  G  + S   G +  KP       ++      + 
Sbjct: 2701 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 2759

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G    +    EG P P   W  N   ++     ++T    +S I I    R  +  Y 
Sbjct: 2760 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 2819

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            I   N  G  + +  + V D P  PEGP+ + EI +E  T+ WKPP D+GG ++  Y +E
Sbjct: 2820 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 2879

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
            K +     W +V     D  T  + KL    EY FRV A N  G S+ LE+ EPI+ K  
Sbjct: 2880 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 2937

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
             DVP            D + + I W P+  NGG+P+  Y VE K++G   W         
Sbjct: 2938 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 2996

Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879
                  L     Y+FR+ A N  G S P   +D +IT  + L P   +  R   +    +
Sbjct: 2997 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3056

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
             ++ + +         P   + +   +    +   +V    S       + K  D   ++
Sbjct: 3057 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3111

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            +  +N +G     E +++        PS P  PLE+  V  +  + +W  P+ DGGA + 
Sbjct: 3112 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3166

Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             Y +  RD     W+ V      T    +  L+E H Y  R+ A N  G S+ L +DEP
Sbjct: 3167 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 3224



 Score =  242 bits (593), Expect = 6e-62
 Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +K G+ +  +V     P P+  W  N K I + K  +   +   +   + K     +G Y
Sbjct: 1581 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 1639

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             +   N  G   V +N+ +  KP+ P  P  + ++      + W  PE+ G   I +Y +
Sbjct: 1640 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 1699

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            E        W+       T  ++ +L     Y+FR  AVN    SD  ET     ++ + 
Sbjct: 1700 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 1757

Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530
                P  ++P +   T+ + D ++L        GG P  +    +  K  + + A     
Sbjct: 1758 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 1815

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585
             +               ++ +A N  G  + S     V+   +     I  + +K    K
Sbjct: 1816 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 1875

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             G        + G P P V W+   N+ + N     +   E  S + +K+++R  S  +T
Sbjct: 1876 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 1935

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            I+A N  G     V + V DKP+ P GP+ + ++  + VT+ W+ P DDGG+ +  Y IE
Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 1995

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
            K++  + RW+  A V  D  T  +  L    EY FRV A N  G S+ LE+    + K  
Sbjct: 1996 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2055

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820
             D P            D + V + W P   +GG+PI +Y VE+K E    W         
Sbjct: 2056 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2114

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
               A +  L   + Y+FRI A+N+ G   P  S   +   + + PP   RN +       
Sbjct: 2115 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2173

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
                    P S   +P   +  E   V+     K+    G    H ++     D   + I
Sbjct: 2174 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 2232

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
             AEN  G    T    V +  H   PS P  PL++  +  +    +W  PE DGGA +  
Sbjct: 2233 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 2287

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            Y I  +D     W   G  +     F++ DL++ H Y  R+ A N  G S+PLE+ E
Sbjct: 2288 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 2342



 Score =  235 bits (575), Expect = 1e-59
 Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%)

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            + RIK G+ + L + ++  P P  +W  N   I        +    S+++ I      D 
Sbjct: 2756 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 2815

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414
            G+YK+ +EN  G    + NVT+LD P  P  P  I EI      + W  P + G + +++
Sbjct: 2816 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 2875

Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            Y+VE  +     W  V         +  L     Y FR  AVN    S   E  E     
Sbjct: 2876 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 2935

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
             +  +  P V+KP      +   DI+   T   GG P   VT Y   KK K +    E  
Sbjct: 2936 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 2991

Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582
                               ++ IA N  G  + S     Q       KP I  ++  IK 
Sbjct: 2992 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3051

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K        V  +  G P P   W    +      E  +  K  T+ I     KR+ S  
Sbjct: 3052 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3109

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y ++  N  G       + V D+PS PEGP+ + +++++S  + WKPP DDGG E++ Y 
Sbjct: 3110 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3169

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
            +EK +   N W+ V+       +  + KL E  EY FRV+A+N  G S++L + EP++ K
Sbjct: 3170 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 3228

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819
                 P            DN+ + I W P   NGGSP+  Y +E K  + G+  K     
Sbjct: 3229 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 3287

Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870
                A    R+QK     TY++R+ A N+ G   P  S    T       P        +
Sbjct: 3288 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 3344

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
             F V       +T+ +T       SP  +  I +    GK    + T   S  +  I + 
Sbjct: 3345 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 3395

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988
            +  D    +I A N  G +      ++++    TV   P AP  I    V  +    +W 
Sbjct: 3396 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 3447

Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             P+ DGGA + GY I  ++V   +W +V  + ++   + +R L     Y  RI A N +G
Sbjct: 3448 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 3506

Query: 2049 LSE 2051
            LS+
Sbjct: 3507 LSD 3509



 Score =  234 bits (572), Expect = 2e-59
 Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350
            D  +   +K G+ V   V     P P  +W   N ++    + T  +  ++   L I   
Sbjct: 986  DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1045

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
              +D G Y+L ++N+ G  + + N+T+LD+PS P  P  + ++   ++N+ W  P++ G 
Sbjct: 1046 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1105

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
              I YY VE  +  T  W+    +  T+  I  LK   +Y+FR  AVN+   SDA  T  
Sbjct: 1106 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1164

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524
                 K+TK ++P  ++P K  T +  + D +   +    P+      +T Y   KK K 
Sbjct: 1165 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 1218

Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574
             +   E      ++               ++  A N  G  E S     VV   +     
Sbjct: 1219 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 1278

Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
            I  E +K    KVG++      + G PPP+  W  N  K  +D++  I +++  +   ++
Sbjct: 1279 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 1337

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
               R H+  YT+ A+N +G+    V + V  KPS P GP+ +  +  +   +EWK P DD
Sbjct: 1338 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 1397

Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
            GG  +  Y IEK +    RW+     +    T  +  L    EY FRV A N  G S+ L
Sbjct: 1398 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 1455

Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
             +   I+ K   +VP            D + V + W  +  +GG+PI  + +E K +  +
Sbjct: 1456 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 1513

Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
            W+           A +  L     YQFRI ARN+ GT  P    D++        P   R
Sbjct: 1514 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 1573

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
              +   +     TLK+        +P   +    K + G+S  +I      +    +   
Sbjct: 1574 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 1631

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
              K    + I+A N  G    T+S ++ + K  + P+ P  P+E+  V  +     W  P
Sbjct: 1632 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 1686

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            E DGG P+  Y I   +    +W+  G+       F +  L++   Y  R+ A N  G S
Sbjct: 1687 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 1744

Query: 2051 EPLESD 2056
            +PLE++
Sbjct: 1745 DPLETE 1750



 Score =  223 bits (545), Expect = 4e-56
 Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
            D  +   IK G  ++  V     P P   W   +++ I+     K       + L +K++
Sbjct: 1867 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 1926

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
            E  D+G + ++  N  G  +  + + ++DKP+ P  P ++ ++    + + W  P++ G 
Sbjct: 1927 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 1986

Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
              I  YV+E  +  +  W+    +   KT   +  L     Y+FR   V  V+    S+ 
Sbjct: 1987 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2043

Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518
             E +     T +     +KP K     IT    + ++L        GG P +  V   +D
Sbjct: 2044 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2099

Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572
                           +               ++  A N  G        S V   +  P 
Sbjct: 2100 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2159

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            +   N   + K K G ++ +   + G P P + W   G  +E+D    +  ++  +   +
Sbjct: 2160 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 2219

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
            K   RS +  Y I+A N  GT + EV + V D PS P GP+ +  I ++   + WK P D
Sbjct: 2220 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 2279

Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
            DGG E++ Y IEK +    RW    +  +D   + +  L +  EY FRV A N  G S+ 
Sbjct: 2280 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337

Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
            LE+ E I+ K   D  +           D +   + W P   +GG+PI  Y VE++    
Sbjct: 2338 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396

Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
             W            A +  L    TYQFR+ A N+ G S P      +        P   
Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456

Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
            R+  V++      TL +        +P   + +    +     T I     +  +   ++
Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
                D   ++I A N  G     +   V +     +P  P  PL  + +    V+  W  
Sbjct: 2517 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 2571

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            P  DGG+P+  Y +  +      W+  G+    +LK N   LSE H Y  R+ A N  G 
Sbjct: 2572 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 2628

Query: 2050 SEPLESD 2056
            S PL SD
Sbjct: 2629 SAPLTSD 2635



 Score =  209 bits (510), Expect = 7e-52
 Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%)

Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
            ++  ++ G  + + + Y    P+P  +    +  I + + T   ++     +T    + +
Sbjct: 3736 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 3795

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
            DAG YK+   N  G    ++NV +LD P  P  P    +I + ++ + W  P++ G   I
Sbjct: 3796 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 3855

Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
              YVVE +     +W++V +   T   ++NL  N+ Y FR  A N+  + +  ET +   
Sbjct: 3856 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 3912

Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528
            ++ +    +P    +P    T+E    ++ T     GG P Q  V   R+    +  KA 
Sbjct: 3913 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 3972

Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583
            + N                Y  +  A+N  G+ E    S  +     P     N  +  +
Sbjct: 3973 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4032

Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639
              +   G+   +       P P+V + K  NK+   D    +   +  + + I++ + + 
Sbjct: 4033 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4092

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
               Y +E  N+ G+ S  + LKV DKP+ P+  + + +I+ +  T+ W PP  DGG  +T
Sbjct: 4093 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4151

Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
             Y +EK +    + +W KV+   R++  Y +  L ++  Y FRV A+   G SE  E ++
Sbjct: 4152 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 4210

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813
             +V K   +VP+           D+    + W P  ++GGS II Y+V+ +     +W  
Sbjct: 4211 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 4268

Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                      AR+  L  N  ++FRI A+N  G S P    ++  +     PP  P +  
Sbjct: 4269 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 4328

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
                     T+ W  P  +GGS IT Y +E +      WT          E  ++ ++E 
Sbjct: 4329 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 4388

Query: 1934 DEIIFRISAENTVGVSLPT 1952
            ++  FR+ A N  G  +P+
Sbjct: 4389 NDYEFRVVAINAAGKGIPS 4407



 Score =  199 bits (485), Expect = 8e-49
 Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%)

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391
            +D  + +L +  + N     ++++  NN G ++    +    I D   +P  PG+P I +
Sbjct: 833  VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 892

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
             D+  I+I W+ P   G + I  Y+VE ++ DT EW  VK +  T  SI  LK    Y+F
Sbjct: 893  FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 952

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
            R  AVN+      SE +E  ++ K   I +      LK+IT +    +      GG P P
Sbjct: 953  RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1011

Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            +V W++  ++L+   + T + R                   Y+    N HG  E    + 
Sbjct: 1012 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1071

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625
            +  +P  +  N  ++      D   ++         E I Y    KL+     +    K 
Sbjct: 1072 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1129

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679
            K +   I  LK+  + ++ ++A N  G S    T K       YD+P K   P ++ +  
Sbjct: 1130 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1188

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             + V++EW+PP  DGG  +T+Y IEK       W +   V  D     I  L E  EY F
Sbjct: 1189 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 1248

Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            RV A N  G  EA + S  +V K     P           ID E++      + K G   
Sbjct: 1249 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 1295

Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
              D  V  +   KK W            RI+     T +  R   R   G    T+   +
Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355

Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
              DK ++    L  PS P     VS        L+W  PE +GG+PI +Y IE   +   
Sbjct: 1356 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 1415

Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968
             W   V  G S   +  + N++   E  FR+ A N  G S P  + +  L K+   VP  
Sbjct: 1416 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 1472

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
               P E+     + V  +W  P+ DGGAP+  + I  +D     W E   V  +     +
Sbjct: 1473 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 1529

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             +L E   Y  RI ARN+ G  +P +  +
Sbjct: 1530 PNLKEGEEYQFRISARNKAGTGDPSDPSD 1558



 Score =  191 bits (465), Expect = 2e-46
 Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%)

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
            W   +  ++D +K  + S+  K   ++R  T      YT    +A  + K  VEV+    
Sbjct: 1311 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 1369

Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
               P   ++    Y  +  +D+   V       P D + +    +   +   P   S++ 
Sbjct: 1370 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 1426

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
              T+  ++      +++R  N  G +D +  N  IL K     P    KP +++ D   +
Sbjct: 1427 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 1486

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
            ++ W+ P++ G + I  +V+E ++ +    E + V    KT T + NLK    Y+FR  A
Sbjct: 1487 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 1544

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514
             N+    D S+ ++  +V+ + +  +P + +  L + T +    ++      G P P VT
Sbjct: 1545 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 1602

Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            W  +GK +  +KA  EN                   Y   A N +G    +  + ++ KP
Sbjct: 1603 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 1662

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626
                     K   +V D +   A ++  PP +     + +Y+       D  +    +  
Sbjct: 1663 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 1716

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680
             +   +  L +    K+ ++A N+ G S       ++  K  +D+P +P  P    +   
Sbjct: 1717 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 1775

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
            + V ++W PPL DGG  + +Y IEK      RW     V     T  +  L  N EY FR
Sbjct: 1776 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 1834

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            V+A N  G S+  ++   VI    ++                   I++        +P +
Sbjct: 1835 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 1894

Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
             +     +E   G + K           ++++    +  F I A N  G      +  KI
Sbjct: 1895 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 1951

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916
             +    T P+ P +  VS+     VTL W  P+ +GG PI NY+IE + T  G+ W    
Sbjct: 1952 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2008

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975
             V G      ++ +    E  FR++A N  G S P E+    L K     P    AP EI
Sbjct: 2009 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2067

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
                 + V   W  P  DGGAP+  Y + ++D     W +V  V        + +L E  
Sbjct: 2068 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2127

Query: 2036 TYMIRIYARNEIGLSEPLES 2055
             Y  RI A+N+ GL +P +S
Sbjct: 2128 KYEFRIRAKNKAGLGDPSDS 2147



 Score =  190 bits (463), Expect = 4e-46
 Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%)

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392
            P + S +A  T++ +E+     +++R EN  G +D    V ++ K    PPG P+  EI 
Sbjct: 3476 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 3534

Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447
              D++ +++ W+ P + G S I+ YVVE +++    +W  VK   +  T+  +  L  N 
Sbjct: 3535 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 3594

Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
            +Y+FR  AVN     + S  +E       V K     +P V K  KN + E   +  L  
Sbjct: 3595 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 3653

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
              GG P     +  + KKL     T  N                     ++ IA N  GE
Sbjct: 3654 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 3709

Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             E S    +V I++   +P+  I+N +DI  +   G+   +     G  P  +I   NGN
Sbjct: 3710 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 3767

Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
                EN++   +       VI     KRS +  Y I A+N  G  + ++ + V D P KP
Sbjct: 3768 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 3826

Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
             GP+   +I  +++T+ W+PP D+GG  +T Y +EK  P  + W+ V        T  ++
Sbjct: 3827 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 3883

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
             L+ N  Y FRV A+N  G  E LE+ + IV K   D P              E++ + W
Sbjct: 3884 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 3942

Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845
                 +GG+PI  Y +E ++ G  +W             R+  L+   TY+FR+ A N  
Sbjct: 3943 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4002

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904
            G      +   IT     T P      +  +  +      K   P +   +P   +    
Sbjct: 4003 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4062

Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
              +        V     +    IE  +  D  ++ +  EN+ G    ++S S+RL+    
Sbjct: 4063 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4114

Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020
            V   P +P  IR+  +  +     W  P  DGG+P+  Y +   D+  +   W +V    
Sbjct: 4115 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4173

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            V  L + +  L +++ Y  R+ A  + G+SEP E
Sbjct: 4174 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4207



 Score =  183 bits (445), Expect = 5e-44
 Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
            S+T+ K+       +++  EN  G +D +  +  +L K     P  PG+P I++ D+  I
Sbjct: 3191 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 3250

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
            +I WD P + G S + +Y +E ++  T  WI V    +  T  S   ++   +Y +R  A
Sbjct: 3251 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 3310

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513
            VN+      S+++       +   ++P  +  L  K    +  E + +T  F   PQP +
Sbjct: 3311 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 3368

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
            +W ++G K      T +++                K  A N +GE E +  + +  KP  
Sbjct: 3369 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 3428

Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631
              +       +H     W       G    E+  YK   +    + ++ +      +   
Sbjct: 3429 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 3485

Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686
            ++ L+     ++ I A N  G S     V V +K  +D P  P  P I    + + V++ 
Sbjct: 3486 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 3544

Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
            W PP DDGG  +  Y +E+ E      W  V  +     T CI   L+EN  Y FRV A 
Sbjct: 3545 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 3603

Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N  G  E    SEP+  +  ++ P             N S  +TW    ++GG+PI  Y 
Sbjct: 3604 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 3662

Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
            VE K+ G   W              ++ L     Y+FR+ A N  G   P    D + I 
Sbjct: 3663 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 3722

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919
            +    P    N +   +     T++   P + G   PI +       +     T +V V 
Sbjct: 3723 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 3781

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
                       K  D   ++ISA N  G      +  V        P  PT P+    + 
Sbjct: 3782 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 3836

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
            ++ +  SW  P+ +GG  +  Y +  R      W+ VG     TL+  +R+L  N  Y  
Sbjct: 3837 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 3893

Query: 2040 RIYARNEIGLSEPLESDE 2057
            R+ A N+ G+ EPLE+D+
Sbjct: 3894 RVRAENQYGVGEPLETDD 3911



 Score =  178 bits (434), Expect = 1e-42
 Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            D P P  KP + + D   I+I W+   N G + +  Y+VE +E  +  W        T  
Sbjct: 2939 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 2998

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            S  NLK    Y FR  AVN    SD S+ T+    I + +   P +    + I  +    
Sbjct: 2999 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3056

Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554
              L   F G P P  TW   D       +   + +                  YK    N
Sbjct: 3057 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3116

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            + GE E    V +Q +P         +   +V D    + V+   PP +    +  N + 
Sbjct: 3117 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3170

Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665
              ++    T    S       I + +L   H  ++ + A NT G S S+     V  K  
Sbjct: 3171 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 3230

Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
               P KP  P I+ +   + + I+W PP D+GG  +  Y IE+ +    RWIKV      
Sbjct: 3231 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 3289

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779
               +   ++ +   Y +RV+A N  G  +  +S      K   + P              
Sbjct: 3290 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 3349

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837
              E + IT  P      SP  D  +   +EG K            +  I     + +   
Sbjct: 3350 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 3403

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
            +I A N  G +    ++ KIT+   +  P  P N      +  + TL W  P+ +GG+ I
Sbjct: 3404 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 3457

Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
              Y IE++ V  + W K+   + G+ +   +  ++   +  FRI AEN VG+S   +   
Sbjct: 3458 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 3515

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015
            V ++     P  P+ P EI    +N V  +W  P  DGG+P+LGY +          W  
Sbjct: 3516 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 3574

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            V    V   +  +  L EN TY  R+ A N  G  EP    EP    P
Sbjct: 3575 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 3622



 Score =  176 bits (428), Expect = 6e-42
 Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P+I+ + ++       +A F  E   + +   RW ++G E+  S+  +        K  I
Sbjct: 4423 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 4482

Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218
             +    DAGEY+ EV    G+   TA L V+ P +     +P  IL   +      Y + 
Sbjct: 4483 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 4541

Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
              P     V   ++  +   T +     D    T+      E  + EYT      ++TT 
Sbjct: 4542 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 4601

Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
              + V   P      +    I      T  + ++  P  +    + S +++K   +K   
Sbjct: 4602 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 4655

Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387
            +  + +  +K +     G+     Y+ R+    EN  G   V  +  I   P  PP  P 
Sbjct: 4656 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 4715

Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443
               I+++    + + W  P + G   +  Y+VE QE +  EW           +  + NL
Sbjct: 4716 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 4775

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
                 YR+R +AVN+  +SD +E  +       +  + P +  PL ++  E    +   C
Sbjct: 4776 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 4834

Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559
               G P+P+  W++  K+L  T+K T  N+                  Y C A N  G  
Sbjct: 4835 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 4894

Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             T   + I+ KP + I  +     + + G+   +    +  P  E  W K+G K+EN+ +
Sbjct: 4895 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 4954

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
            ++ITT +K + +RI    R    +Y +   N+ G+ S  V + V D P  P  P+I   I
Sbjct: 4955 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5013

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737
              E+V + WKPP  DGG  +T Y IEK E     W   A   +   TY  I+ L    +Y
Sbjct: 5014 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5070

Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760
             FR+IA+N  G S+  E + P++I
Sbjct: 5071 EFRIIAENKHGQSKPCEPTAPVLI 5094



 Score =  171 bits (416), Expect = 2e-40
 Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%)

Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R  N  GH +       VT    ++KP  P  P + +I  +S  + W+ P   G + 
Sbjct: 3598 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 3657

Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            I  Y+VE +++   +W     K +  T   ++NL     Y FR  AVN     + S+ ++
Sbjct: 3658 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 3717

Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523
               V+ E +   P  +   LK+IT    E I++   + GG P+P +  +     +    +
Sbjct: 3718 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 3775

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580
            T                       YK  A N +G+        V+    KP   I   DI
Sbjct: 3776 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 3835

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
             Q   +   W       G    + I      K     ++        + +R++ L  +  
Sbjct: 3836 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 3890

Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
             ++ + A N  G      T    V    +D P  P  P  + E S E++T++W  P  DG
Sbjct: 3891 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 3949

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753
            G  +  Y IEK E  +  W K A  +     + +  L     Y FRV A N  G  E ++
Sbjct: 3950 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4009

Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810
             S PI    A   P           +                 +P + +     +I    
Sbjct: 4010 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4069

Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
             + K           I+K  +     + +   N  G      SD      K +  P+ P+
Sbjct: 4070 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4123

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928
            +  V +      TL W  P S+GGSPITNYI+E   ++     W K+ +   +++ + + 
Sbjct: 4124 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4182

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987
             + + +   FR+ AE   GVS P E   V + K+   VP+ P AP  +R   S      W
Sbjct: 4183 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 4241

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046
              P  DGG+ ++GY +  RD +   W+   K+D++      +  L +N  +  RI A+N 
Sbjct: 4242 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 4299

Query: 2047 IGLSEPLESDE 2057
             G S+P    E
Sbjct: 4300 AGFSKPSPPSE 4310



 Score =  163 bits (396), Expect = 5e-38
 Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391
            ++K     +K ++  + G YK R++  N CG +D     ++L K     PGKP   + ++
Sbjct: 537  ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 594

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449
            +D     + W+ PE  G + I  Y++E +E    +W  V         + + K   +  Y
Sbjct: 595  VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 654

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             +R  AVN+    D  +  +  K+ K  K         +K++  +  E I+      G P
Sbjct: 655  LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 713

Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P+  W  +GK LK       ++   +               +     N  G  +++  V
Sbjct: 714  LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 773

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
             +  +P       DI      G         +    P   +      ++N  +Y    K 
Sbjct: 774  TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 833

Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677
               T+ +++  L+   + K+ ++A N  G S   S +   ++   +D+P KP  P I  +
Sbjct: 834  DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 892

Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
               + + I W+PP  DGG  + +Y +E  +PD   W +V  V  D     I  L E  EY
Sbjct: 893  FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 950

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             FRV A N  G  +  E     +     +P+                 + W    K GG 
Sbjct: 951  QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1008

Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
            PI + K      +++   +              I     +   ++R+  +N  G      
Sbjct: 1009 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1064

Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910
             ++K  +   L  PS+P     VS+    ++ L W  P+ +GG PI  Y +E   T  G+
Sbjct: 1065 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1122

Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
             W     V  +   H I+ +K+     FR+ A N  G S    +      K+       T
Sbjct: 1123 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1179

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
               ++    ++ V   W  P+ DGGAP+  Y I  +      W E GKV  +     I  
Sbjct: 1180 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 1239

Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
            L E   Y  R+ A N+ G  E   SD   KV+
Sbjct: 1240 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 1269



 Score =  142 bits (343), Expect = 1e-31
 Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
            P PP       I  +   I W  P   G S I  Y VE +E  +T W   S  N+ + + 
Sbjct: 4321 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 4380

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497
            ++  L+  + Y FR  A+N       S  +   K+ +    +   V KP    T +P N 
Sbjct: 4381 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 4438

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553
                TC   G P+P   W R+G++L ++++  +E                    Y     
Sbjct: 4439 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 4498

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            N +G    +  + +Q  PVI    +D+       GD   +     G  P       N  +
Sbjct: 4499 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 4555

Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
            ++ D     I   +   +I I  L    + +Y    SN +G ++    L V   P  P+G
Sbjct: 4556 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 4615

Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
            P+ +  I   + T+ W+PP+ DGG ++T Y +EK +   + W+ V    +D+  Y +  L
Sbjct: 4616 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 4674

Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
             EN EY FRV AQN  G    L SE PI+ +   D P           +  + V ++W  
Sbjct: 4675 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 4733

Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847
               +GG  +  Y VE  ++E  +W              +  L     Y++R++A N+ G 
Sbjct: 4734 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 4793

Query: 1848 S 1848
            S
Sbjct: 4794 S 4794



 Score =  132 bits (320), Expect = 8e-29
 Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%)

Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
            K T KL V V++ P K     R   I+  +   + + ++  P+ N    + + +++K   
Sbjct: 3810 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 3865

Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384
                +       T  +V N DA     +++R EN  G  + +E +  I+     D P  P
Sbjct: 3866 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 3925

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442
            G+P  +E    +I + W  P + G + I  YV+E +E+ +TEW      NI  T+  +  
Sbjct: 3926 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 3985

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500
            L    +Y FR  A N     + S  +    +  +     P +   +  ++I     E  +
Sbjct: 3986 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4043

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
            +   F   P PKVT+ +   K+       K  Y +                 Y     N 
Sbjct: 4044 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4103

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611
             G    S  + +  KP    S + I+ +    D     W+  +   G P    I  K   
Sbjct: 4104 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4160

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
            +  + K   +++  +     +  L + +  ++ + A    G S       V V    ++ 
Sbjct: 4161 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 4220

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P++PE P + R+       +EW PP  DGG ++  Y ++  +  + RWI  A +D   + 
Sbjct: 4221 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 4277

Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
            +  +  L +N E+ FR+IA+N  GFS+ +  SE   +K+    P           I    
Sbjct: 4278 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 4336

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
              ITW    ++GGS I  Y VEI++ G   W              + KL     Y+FR+ 
Sbjct: 4337 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 4396

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
            A N  G  +P      I I +  +  S+P+  V  E T++
Sbjct: 4397 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 4434



 Score =  129 bits (311), Expect = 9e-28
 Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%)

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
            C  ADV +     + P+ P  P + + DS+   + WD P + G S II Y V+Y++  + 
Sbjct: 4206 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 4264

Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
             WI+ K     Q    +  L+ N  + FR  A N    S  S  +E  ++        P 
Sbjct: 4265 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 4324

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537
            +    K+I         +  +  G    K+T Y    R+ G  L T  + Y  R      
Sbjct: 4325 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 4382

Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590
                      ++ +A N  G+   S   G   IQ+    +P I +  ED  Q +     +
Sbjct: 4383 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 4442

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
               AV  G P P   W +NG +L     Y     +      IKE+    + +YT+E SN 
Sbjct: 4443 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 4500

Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
             G+ +    L V   P     PVI +++     TI     L  G L   K       P  
Sbjct: 4501 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 4546

Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766
            +  +    ++D D  T  I + +++       ++    G  E   S      T    L+V
Sbjct: 4547 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 4606

Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
               P           I   +  ++W P   +GGS I  Y VE +   K +W         
Sbjct: 4607 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 4666

Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
               I   L  N  Y+FR+ A+NE G   P  S+  I       PP+ P N  + +     
Sbjct: 4667 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 4726

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
            VTL W  P S+GG  +  YI+E +  +   W +        + + + N+ +  +  +R+ 
Sbjct: 4727 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 4786

Query: 1942 AENTVGVS 1949
            A N  G+S
Sbjct: 4787 AVNDAGLS 4794



 Score =  124 bits (299), Expect = 3e-26
 Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%)

Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
            W P   +GGSPI +Y   K++++    KW K           +  L  +  Y+FR+ A  
Sbjct: 4139 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4198

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
            + G S P    D +        P+QP    V +  S    L+W +P  +GGS I  Y ++
Sbjct: 4199 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 4257

Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
            ++      W   +     + E C   +  +++  E  FRI A+N  G S P+  S+  +L
Sbjct: 4258 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 4314

Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
            +     P PP   +  + +G N    +W  P  DGG+ + GYN+ IR+   T+W      
Sbjct: 4315 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 4373

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067
            +V   +F +  L E + Y  R+ A N  G   P     P K+    GS
Sbjct: 4374 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 4421



 Score =   99 bits (238), Expect = 7e-19
 Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%)

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P   I WY++ + I       +    +N+  +I N     D+G Y C A+   G  +H  
Sbjct: 45   PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 101

Query: 920  RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
               ++   K +F+  L  + E    K  +L C+ +       WY   K I   D R II+
Sbjct: 102  LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 161

Query: 978  E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
            +   GR                   I +D  +   + V+E    F+  ++  +V E D+A
Sbjct: 162  KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 221

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
             LE ++N + A+VVW  DG+ I     K+  E     R+L I    + D GEY C  +D+
Sbjct: 222  TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 281

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152
               A++ +V+   + I  L++ +V + +  T   +         WF++G +I        
Sbjct: 282  RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 340

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
            +         LKI   ++++A  Y  +    + +  +TV E
Sbjct: 341  ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 381



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%)

Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            P  P+  + +++ T+  + L W  P+ + G+P+  YIIE +  +  +W K+    G+  +
Sbjct: 485  PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 542

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
              ++++KE  E  FR+ A N  G+S P   +SV  +    VP  P   ++   V  +   
Sbjct: 543  FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 601

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
             +W  PE DGGAP+ GY I  R+ ++  W +VG+   +  +   + + E+  Y+ R+ A 
Sbjct: 602  LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 661

Query: 2045 NEIGLSEPLESDEPFKV 2061
            N+ G  +P +  +P K+
Sbjct: 662  NKAGPGDPCDHGKPIKM 678



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%)

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931
            +S     + TL W  P ++GGS IT+Y++E + +    W   VTV  +V +  + +  + 
Sbjct: 4619 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 4675

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988
            E  E  FR+SA+N  G+  P  S+   +   A +P  PPT+P  LEI  VG + V  SW 
Sbjct: 4676 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 4732

Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             P  DGG  L GY +  ++     W    +       +N+ +L +   Y  R++A N+ G
Sbjct: 4733 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 4792

Query: 2049 LSEPLESDEPFKVIPGEG 2066
            LS+  E D+      G G
Sbjct: 4793 LSDLAELDQTLFQASGSG 4810



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%)

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666
            L  D+   +T+  K     +  L  +H  ++ + A N  G      S   +  ++ +D P
Sbjct: 4652 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 4711

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
            + P    I+ ++  + VT+ W+ PL DGG  L  Y +EK E +++ W +          Y
Sbjct: 4712 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 4770

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             +  L +  +Y +RV A N  G S+  E +  + + A               ++ E    
Sbjct: 4771 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 4829

Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
              F  E + GSP  +Y+     +   +  K+            I  L+ +   ++   A 
Sbjct: 4830 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 4888

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
            N  GT     +    T  +   PP     +       +  T++   P          +  
Sbjct: 4889 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 4944

Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            + + ++  S   I T         I N   +D   +R+  EN+VG    T + +V     
Sbjct: 4945 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 4998

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
            A VP PP  P+ I  +    V+ SW  P  DGG+ +  Y I  R+     W    K    
Sbjct: 4999 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5057

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
                 I  L     Y  RI A N+ G S+P E   P  +IPG+
Sbjct: 5058 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5097



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%)

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
            T LDVP           I  E   + W P   NGG+ ++ Y VE     +  W+      
Sbjct: 2836 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 2895

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
               A++ KL     Y FR+ A N  G S P  +++ I        P       V++    
Sbjct: 2896 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 2955

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
             + +KW    +NGG+P+T YI+E K      WT+     G+      +N+K   E  FR+
Sbjct: 2956 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3013

Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996
             A N  G S P++    ++ K   + P   TA  +I++      N+ +   G P+     
Sbjct: 3014 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3068

Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            P   + +          + V  K    ++ F     +++  Y +++  +NE+G     E 
Sbjct: 3069 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3121

Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
            +  F+VI  +   A E P E ++V
Sbjct: 3122 EAIFEVIVQDRPSAPEGPLEVSDV 3145



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787
            E +P  +++P  +  V +G+S     +V+ +  P +TW K+++ +K       + +G+ +
Sbjct: 5472 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 5530

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
             +TI + K   D+G YT++A+NS G  E    + V   +E     PL      E   K  
Sbjct: 5531 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 5583

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905
               ++     R   P  T++  N +I  +    +T +  G     +    D      D  
Sbjct: 5584 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 5643

Query: 906  CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965
             V+  S   S       +D +  T+          +  + V+       TV TK      
Sbjct: 5644 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 5695

Query: 966  EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019
             +S    R   + +  G                +I+ +  D +  +  L  K T  +P F
Sbjct: 5696 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 5755

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
              +L D E +    A     ++ +   ++ W  +GE I    +++          L I +
Sbjct: 5756 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 5815

Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120
                DEG+Y C   +    E   A +TV              VE    +   L  + VN 
Sbjct: 5816 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 5875

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
            G   TFE  +      V W ++G E+   +   ++ DG+     I   D  DAG Y  EV
Sbjct: 5876 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 5935

Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
             +         +++ V E +     RLP  +  P       T+E  + E L V W++   
Sbjct: 5936 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 5995

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
             IE  E+   +       L I+   +DD   Y   ++  K
Sbjct: 5996 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6035



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P PE  W+K   +L +  +Y +  K    V+ I +L    + +YT  A+N++GT S
Sbjct: 4836 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 4895

Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
                L++  KP     P       +++  TIE K P         ++  +  + +NN   
Sbjct: 4896 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
             +   D+   T  I   +      +RV+ +N VG          V  T  DVP       
Sbjct: 4956 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5009

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833
                +D E+V ++W P   +GGS + +Y +E ++  G  W            I+ L    
Sbjct: 5010 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5068

Query: 1834 TYQFRIYARNEIGTSLP 1850
             Y+FRI A N+ G S P
Sbjct: 5069 QYEFRIIAENKHGQSKP 5085



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%)

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
            +P  P  PL I  +G +    SW  P  DGG+ +  Y +  RD++K  W+ V   +V  +
Sbjct: 4609 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 4667

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             + +  L ENH Y  R+ A+NE G+  PL S+ P
Sbjct: 4668 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 4701



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%)

Query: 708  YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            Y V AVN  G    A L   L   +G  E P+++ PL  +    G  V    ++ G+PRP
Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842

Query: 765  TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
               W   CK           + GD   + I+      D   YT +A NS G   T A + 
Sbjct: 4843 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 4901

Query: 822  VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            ++       +P +FI  ++      +KG TI+L       P     W ++ E I  +   
Sbjct: 4902 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +   D +   L I+N   E D G+Y+ V  NS G  S    VT+
Sbjct: 4956 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 4998



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+ K       +G +  F C+V     P +TW +    +K S  +   Y+ ++   L 
Sbjct: 5475 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 5533

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I  V  +D G +T  AKN+ G    T E IV   ++ H   +                + 
Sbjct: 5534 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 5589

Query: 630  E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
            E       P F+   + + + +     L C L   P P I W+  G   V ++ + V+  
Sbjct: 5590 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 5648

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737
            S +   CS L+I N +    GTYTV A N  G      VL ++T   EP P+V
Sbjct: 5649 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 5697



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P+F+ +      + G        +   PEP I WL  GE I   ++      +      +
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 5809

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742
             L+I++ KK  EG Y   A N  G+      L +K  +           +   +V + L 
Sbjct: 5810 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 5869

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799
              IV  GESV   A+V G P   + W +N + +          DG+T S TI       D
Sbjct: 5870 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 5927

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858
             G Y L+   S+G    S    V     E A+PP  + R    ++    G+         
Sbjct: 5928 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 5982

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
                ++ W+R +E I  +E +     G   +L I NV+ + D G Y
Sbjct: 5983 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6027



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790
            E P     L       G S   SA V G P P I W  N + +    ++          T
Sbjct: 5751 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 5810

Query: 791  I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842
            + +   K  DEG Y  +A NS G  +T A +TV  ++P       +  E  L + +    
Sbjct: 5811 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 5870

Query: 843  TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
             +   G ++   ARV   P   + W RN + ++  +  + + DGE +   I + D+  D+
Sbjct: 5871 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 5928

Query: 902  GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958
            G Y+  V S      S  + V +  +    V  L  S     G +    +E +    ++ 
Sbjct: 5929 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 5988

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005
            +W+   ++I   +  + ++ G             D G+ +  +VK+++
Sbjct: 5989 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6036



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568
            P F  +L    T  G + +F   V G P P I W      I  S   F+  Y     ATL
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 5811

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626
             I +    D G + C A N+AG   +   L V  + PL +  +   V             
Sbjct: 5812 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 5862

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
                      +K    + V+ G  +  E R+   PE ++ W+  G+E+   +  S++ + 
Sbjct: 5863 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 5913

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            +   +     I +      G Y  + V  +G   + +   +  GEK  P V     S+  
Sbjct: 5914 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 5968

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
              G S   + +       T+ W + ++ +   + + +   G+T  + I K  +  D+G+Y
Sbjct: 5969 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6027

Query: 804  TLK-AENSEGIAETSAVI 820
              K  +  + IA+ +A +
Sbjct: 6028 VAKVVKEKKAIAKYAAAL 6045



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%)

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            VE   E  D  W R  +   P  N Y+       RK   R  +V+D G       D++  
Sbjct: 4747 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 4804

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
                  E  P+I++ L +     G   TFE E++       RWFK   E+  ++   L  
Sbjct: 4805 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 4863

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209
             G KQ L I D   DDA EY+C   NS  T          N  ++    + +P       
Sbjct: 4864 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 4918

Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
             A     + ++IP +     +  W K    IE+  KF++ +D K  TL I   + +D  E
Sbjct: 4919 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 4978

Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289
            Y  V+ ++      T  + V  V  PP+
Sbjct: 4979 YRVVVENSVGSDSGTVNVTVADVPEPPR 5006



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%)

Query: 704  QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
            +E  + VVAVN+ G     +AS  ++ K +    +P    + LK++ ++ G+S+     V
Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 1886

Query: 759  VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
             G P PT+TW   +N+ ++     K D  +  S  ++K  +  D G +T+KA N+ G  E
Sbjct: 1887 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 1946

Query: 816  TSAVITV-EEPTEEN 829
             +  I V ++PT  N
Sbjct: 1947 ATVKINVIDKPTSPN 1961



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y + A N  G+++ + +         + E P  ++   ++  +    +     ++ +P P
Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842

Query: 863  SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
               W++   E++  S+    N  G+   L+I ++ S+ D+ +Y C A+NS+G  S  A +
Sbjct: 4843 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 4900

Query: 922  TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978
             I  +   F+       YE ++G+T+ L+   +       +W  + ++I       I  +
Sbjct: 4901 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 4960

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018
             +            D G  + +V++    ++ T+ V    +PE
Sbjct: 4961 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5003



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747
           C  L    V + +E  Y V AVN+ G    P      +K+K  +  P      +K + ++
Sbjct: 640 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 698

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
            GE++     + G P P   W  N KP+KA+            I+K +     D G +T+
Sbjct: 699 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 758

Query: 806 KAENSEGIAETSAVITV 822
             +NS G  +++A +TV
Sbjct: 759 TLKNSSGSCDSTATVTV 775



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  V  L   +   G  V FEC++ G PRP+  WF+    +  +  + +    D    L+
Sbjct: 4813 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 4871

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            I ++  +DA  +TC A N++G  S+   L ++
Sbjct: 4872 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 4903



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%)

Query: 696  KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
            +I  +K+ +E  + V AVN+ G  EAS P    +       P +  E +K++ ++ G  V
Sbjct: 1236 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 1295

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811
                 V G P P   W  N KPV     + + + +    +L+    K  G+YTL A N+ 
Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355

Query: 812  GIAETSA-VITVEEPT 826
            G  + S  VI + +P+
Sbjct: 1356 GSDKHSVEVIVLGKPS 1371



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%)

Query: 492  IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
            I  LP       E     P  V K      P      F C+  G P P   W R    + 
Sbjct: 4405 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 4464

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             S  ++ +   D V    I+EV+  DAG +T    N  G  ++T  L+V+AP
Sbjct: 4465 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 4515



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
            I+ +K+ +E  + V AVN+ G  + S P   ++   +  P  +  + LKS+ V+ G +V 
Sbjct: 941  ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1000

Query: 754  LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
               ++ G P P + W K N+ ++    L   +  + H+I  +      D G Y L  +NS
Sbjct: 1001 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1060

Query: 811  EGIAETSAVITV-EEPTEEN 829
             G  E  A +TV + P++ N
Sbjct: 1061 HGADEEKANLTVLDRPSKPN 1080



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%)

Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529
            +TKI +  P+    L +  TE     E +    G P+P + W  +G+++  +    +A+Y
Sbjct: 5745 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 5804

Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581
               +               Y C A N  G+ +T   + ++  +P++       + +E   
Sbjct: 5805 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 5864

Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
             KH        G+     A ++G P  EV+W +NG +L N  + +I+   +T    I   
Sbjct: 5865 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 5923

Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669
              S +  Y +E   + GT+ V V +L V  + + P
Sbjct: 5924 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 5957



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
            P    +L + +   G  A F   ++ + + L+ W  +G  I  S+   + +    K  L+
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 5812

Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207
            I D    D G+Y C   NS    +  A LTV  ++P +N          LR+ + +   +
Sbjct: 5813 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 5872

Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
            V           +     +V W +    + + +K ++  D +  +  I      D   Y 
Sbjct: 5873 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 5932

Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
              +     +  S   L V   +  P +           G      ++++       +W  
Sbjct: 5933 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 5992

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             S+ I+K +  K      +  L IK VE  D GIY
Sbjct: 5993 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6027



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%)

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740
            + SD ++      +  +++F +  + VVA+N  G+   SLP   +KI+      PQ++  
Sbjct: 4369 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 4428

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796
             +          + + + VG P PT  W +N + +          SDG  +  TI +   
Sbjct: 4429 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 4487

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEP 825
            + D G YT++  N  G    +A + V+ P
Sbjct: 4488 I-DAGEYTVEVSNPYGSDTATANLVVQAP 4515



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 32/121 (26%), Positives = 48/121 (39%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + +KA N  G +  S           +  P +  + F    VK   T+     V   P P
Sbjct: 2424 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 2483

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             I W+ N   +S       + + +N   + T   +  DSG YK VA+N +GK  H   V 
Sbjct: 2484 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 2543

Query: 923  I 923
            I
Sbjct: 2544 I 2544



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%)

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753
            T V+K     Y VVAVN+ G           T +   E P+    L  K   V+ GE ++
Sbjct: 3296 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 3355

Query: 754  LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            ++     +P+P I+W K   KP+  + T    D+ +  ++   +  D G   +KA N  G
Sbjct: 3356 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 3412

Query: 813  IAETSAVITV 822
             AE +  ITV
Sbjct: 3413 EAEANIKITV 3422



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%)

Query: 770  KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            K  K VK +P     DT+ SI+ LK  K   E  + ++A N  G  + S      EP+E+
Sbjct: 926  KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 971

Query: 829  NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
                P FI      +  + ITVK   T++   ++   P+P + W++ N+ +     +T  
Sbjct: 972  QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1029

Query: 883  FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923
             D    E  I  + S +  D G+Y+    NS G     A +T+
Sbjct: 1030 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1072



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            G  +  EC +   P P+  W FKG +E+V     ++  + D      VL I ++      
Sbjct: 4827 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 4881

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
             YT  A N  G  S    L+IKT     P+V  P K       ++GE++ L       P+
Sbjct: 4882 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 4937

Query: 764  PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
                W K+ + ++        +D    ++ I    + +D G Y +  ENS G    +  +
Sbjct: 4938 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 4996

Query: 821  TVEEPTEENAEPPLF 835
            TV +      EPP F
Sbjct: 4997 TVADV----PEPPRF 5007



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754
            + N+K+  +  + + A N+ G              +  P VI+   ++ + V+ G+   L
Sbjct: 2120 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2179

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
            +  V G P PTITW     PV++       +    T    K+    D G Y +KAEN  G
Sbjct: 2180 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 2239

Query: 813  IAETSAVITV 822
                   +TV
Sbjct: 2240 TDTAEVKVTV 2249



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%)

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856
            K+E  + + A NS G  E S    +    E+   P   IN  ++ITV+   TI++ +   
Sbjct: 3694 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 3753

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915
              NP P I  +  N  I  +E      D    E+VIT   S+  D+G YK  A+N  GK 
Sbjct: 3754 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 3811

Query: 916  S 916
            +
Sbjct: 3812 T 3812



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%)

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P PD+ W F G+ I   +     IE++   Y S   +    + Q G YT+ A N  G  S
Sbjct: 1597 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 1651

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779
            + I +K+K+   +P   IE       R            G P       K N K    +P
Sbjct: 1652 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 1711

Query: 780  TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832
                GDTH  T+    K  D   + +KA NSEG +   ET   I  + P +    P
Sbjct: 1712 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 1765



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)

Query: 697  ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753
            + N+K+ +E  + + A N+ G  + S P    +       P++  E L    V+ G ++ 
Sbjct: 1529 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 1588

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812
                + G P P +TW  N K +     + + + +      PK + K  G YT+ A N  G
Sbjct: 1589 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 1648

Query: 813  IAETSAVITVE-EPTE 827
                +  I V+ +PT+
Sbjct: 1649 TDSVTINIKVKSKPTK 1664



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%)

Query: 699  NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            N+K   E  + V+AVN  G  + S P   +I       P+++   + + ++ G +  L  
Sbjct: 3002 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3061

Query: 757  QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
              +G P PT TW   +      P    D  + + +I  P  K  D G Y LK +N  G  
Sbjct: 3062 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3121

Query: 815  ETSAVITVEE 824
            E    + V++
Sbjct: 3122 EAIFEVIVQD 3131



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749
            +  ++ N+ + +E  + V+AVN   EGE S P  ++ I+     P   I  LK + VR G
Sbjct: 3684 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 3743

Query: 750  ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806
            E++ I      GNP+P I     N P+ +   T  D +   I I     K  D G Y + 
Sbjct: 3744 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 3803

Query: 807  AENSEG 812
            A N  G
Sbjct: 3804 ATNKYG 3809



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%)

Query: 482  QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538
            Q+  K LN+  +  P     T  ++ + +AP I  +    +    G T+ F+  VEG P 
Sbjct: 2423 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 2482

Query: 539  PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            P+I WF   + +    +  +  + DN   L  +     D+G +  VA N +G
Sbjct: 2483 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 2534



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + ++A+N  G+ + S   +       N  P +  N  QEI VK      L   V+  P P
Sbjct: 2131 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2189

Query: 863  SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            +ITW +    + S       N DG+    V   + S  D+G Y   A N  G  +   +V
Sbjct: 2190 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 2247

Query: 922  TI 923
            T+
Sbjct: 2248 TV 2249



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%)

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            KN +  +AL    D  T ++  LK     +E  + + A N  G  + S           N
Sbjct: 1510 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 1566

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
              P +      + TVK   T+K +  +   P P +TW  N + I  S+   +N     I 
Sbjct: 1567 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 1624

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
                       SG Y   A+N  G  S    VTI+++
Sbjct: 1625 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 1657



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 524  GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            G ++ F+  V G P P +TW +     I+     ++  + +  + LV++++   D+GTFT
Sbjct: 1877 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 1935

Query: 583  CVAKNAAGFASSTTEL-IVEAPLSDHG 608
              A NA G   +T ++ +++ P S +G
Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNG 1962



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T++ +   + YP+ +  W +    I+ +  F +   DD  ATL I     ED G +  
Sbjct: 4923 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 4981

Query: 584  VAKNAAGFASSTTELIV 600
            V +N+ G  S T  + V
Sbjct: 4982 VVENSVGSDSGTVNVTV 4998



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+  AP F   LR +        +  C ++G P P I W +    +   +D        
Sbjct: 5592 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 5649

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             V +L I     +DAGT+T  A N  G   S   L V+
Sbjct: 5650 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 5687



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G  P    KP+          +  C  V  PEP   WL  G E+   E+     E+   +
Sbjct: 4420 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 4477

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            Y   +K   V     G YTV   N  G  +    L ++     PP + + + + I+  G+
Sbjct: 4478 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 4531

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
             V L     G      +   N + +    PT    + D H +  +    V++ G Y    
Sbjct: 4532 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 4591

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G A T   + V     E  + PL I+     T     T+     VT       ++ 
Sbjct: 4592 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 4646

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                 +S  E +T   + +++  ++T +  E    +++  A N  G
Sbjct: 4647 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 4691



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582
            G+ V+F+  V G P P+  W       KP  D ++  + ++  T  V+R    + AG +T
Sbjct: 1292 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 1348

Query: 583  CVAKNAAGFASSTTELIV 600
              A NA+G    + E+IV
Sbjct: 1349 LTATNASGSDKHSVEVIV 1366



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T  ++G P P + W K+G+ ++ D+   ++ +     + I   +   +  YT+ A+N  
Sbjct: 5617 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 5675

Query: 1652 GTSSVEVTLKVYDKPSKP 1669
            G    E  L V  K  +P
Sbjct: 5676 GVDVSECVLTVQTKGGEP 5693



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753
            +  +K  Q   + V A+N+ GE+  S P    +       P++   +  +  V+ G+++ 
Sbjct: 2413 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 2472

Query: 754  LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
                V G P P I W  N  P+ +   T  D +T + T L  K     D G Y + A N 
Sbjct: 2473 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 2532

Query: 811  EGIAETSAVITV 822
             G  E    + +
Sbjct: 2533 SGKDEHEVDVNI 2544



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%)

Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           KS+ D H +   KP        K V+D E +Y +KA N  G  +        +   + A 
Sbjct: 625 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 684

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
           P       +++ +K   TIK    ++  P+P   W  N + +     +  + +     + 
Sbjct: 685 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 744

Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           I N     DSG +     NS+G     A VT+
Sbjct: 745 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 775



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +  G  VT     Q  P+    W+ N + +     T  S D ++ S TI   + +DAG Y
Sbjct: 5873 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 5931

Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            +L + +       V   V + +K  PP    +  + SS        P   G ST   + +
Sbjct: 5932 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 5978

Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            E++ ++  T +W       +    ++++KT ++++     V + D     +     KV+K
Sbjct: 5979 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6033

Query: 1476 ETK 1478
            E K
Sbjct: 6034 EKK 6036



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            +E  + + A N  G ++ S           N +P +  +  + +T+K   +I     V+ 
Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 1888

Query: 859  NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             P P++TW+   N EI +       N + ++ +LV+  ++   DSG +   A N+ G+  
Sbjct: 1889 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 1946

Query: 917  HGARVTIDVEKVT 929
               ++ + ++K T
Sbjct: 1947 ATVKINV-IDKPT 1958



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544
            L+N   + N   +LTC   G P P + W +DG  +   +     R               
Sbjct: 5604 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 5663

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570
               Y   A ND G   + CV+ +Q K
Sbjct: 5664 AGTYTVTATNDLGVDVSECVLTVQTK 5689



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%)

Query: 503  SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            SE+Q   P F+      + L+      G+TV++E ++ G P P++ WF+    ++     
Sbjct: 969  SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1028

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608
             +    +    L I      D G +    KN+ G       L +++ P   +G
Sbjct: 1029 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1081


>UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin -
            Mytilus galloprovincialis (Mediterranean mussel)
          Length = 4736

 Score =  315 bits (773), Expect = 1e-83
 Identities = 278/1162 (23%), Positives = 486/1162 (41%), Gaps = 49/1162 (4%)

Query: 930  FVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            ++  L     TE  K  I E +        KW+ NK EI          +          
Sbjct: 1099 YIVELDDVKATEGDKKAIFESEFCKKNAKVKWFKNKLEIFAGHKYHFENDNMKYRLVVNN 1158

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQD--FEVKEKDVAILEVEINSET 1044
                D G     +   ++   L V+   P  EF +KL +   + K K+V  LE  ++   
Sbjct: 1159 VKLEDGGKYTLELNGVKSGAWLYVEAKAPHVEFTQKLPEKFSQTKRKEVD-LECFVSDPR 1217

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A V W ++G+ I+ +  K + ++R +   L I++    DE EY+C   D   T +  V +
Sbjct: 1218 ARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTCGDAKTTCQFKVTD 1277

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
               + +  L + +  + ++ATFE ++   +A V+W ++  E+      ++ +DG K++L 
Sbjct: 1278 PEWDFMKLLDDVEGIERDRATFECDVNDPEAEVKWSRNDKELTSGGKYEIQVDGFKRRLV 1337

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            + +C   D G Y+C+V + + TA L V EP + F  +L         T            
Sbjct: 1338 VKNCHSKDDGPYTCKVLDKETTANLFV-EPDVKFFKKLENKREREKGTLVLECKASNPHN 1396

Query: 1225 LDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
              V W K  + + +D  +  +    +   ++I+  T +D  +Y C + +  S  ++ V+ 
Sbjct: 1397 QPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLTREDAGQYACQVGERSSKWEVIVDE 1456

Query: 1284 VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            +  PP+I   D   E  +K+G  + + + +   P P+  W  +   + +   T   +   
Sbjct: 1457 LPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMPSGHWKKDGNPLSEA-DTDIRMTDT 1515

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINIC 1400
             AS+ I   +  D G Y+L L N  G   + + V +LD P  PG+P +++++ +    + 
Sbjct: 1516 LASIRIPDAQRGDTGQYELTLTNEVGSEVIPIPVRVLDVPGRPGEPLDVVDVFADKCALL 1575

Query: 1401 WDEPENTGNSTIIYYVVEYQ--EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
            WD P++ G S I +Y+VE +  E D+  +  V      +  +  LK    Y+FR  AVNE
Sbjct: 1576 WDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQVCTTEDLEVDVTGLKEGHRYQFRVRAVNE 1635

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL----TCIFGGVPQPKVT 1514
               S+     +   + K+     P+      N+     + +E+        GG P  K  
Sbjct: 1636 QGTSEPL-LADGEIIAKDP--WDPSDPPQDTNVEDYDKDYVEIGWKPPISDGGAPIEKYV 1692

Query: 1515 WYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGI 1567
              +  K         E   ++               ++  A N  G+ E    T  V+  
Sbjct: 1693 IEKCEKHRPEWVPGIEVPGDKRAGTVSGLTENREYIFRVSAVNKAGKSEPSEATPPVLTK 1752

Query: 1568 QQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNG-----NKLENDKEYN 1620
             ++    I N+D  +  +V  G ++ +     G P P++ W K G       LE     +
Sbjct: 1753 SRRVRPRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHIS 1812

Query: 1621 ITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            I  K EK S +  KE  R  ++ Y +  +N  G+ + +V + V   PS P+GP+ +  I+
Sbjct: 1813 IDNKTEKKSTLTCKEPSRKDTAMYNVTVTNKHGSDTADVEVVVLGPPSMPKGPIKVSNIT 1872

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             ES T+EW  P D GG  +  Y +EK +    +W  V +  +  +   + KL E  EY F
Sbjct: 1873 AESATLEWGEPEDLGGSPIDGYKVEKMDTKKGQWEPVREGVKGTKV-TVPKLKEGQEYKF 1931

Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            RV A +  G SE LE++PI+ K   D P            D   + + W P E +GG P+
Sbjct: 1932 RVAAMSQNGNSEPLETKPIIAKKPYDEPFPPGQPKCVDR-DRTHIKMKWEPPENDGGYPV 1990

Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
              Y VE K+ +  +W                K+     Y++R+ A N+ G S P  +   
Sbjct: 1991 NSYDVERKEPKTNRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKV 2050

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTVKGKSWTKI 1915
            I        P    + +   +  R    +  + P    G+P      E       +  K 
Sbjct: 2051 IQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAKC 2110

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
             +       H ++  +  D   + I+  N  G S+  +   + L+K    P  P  PL +
Sbjct: 2111 TSSEEDAKLH-VDKAERGDTGKYTITVTNESG-SMSADVNVIVLDK----PGAPEGPLAV 2164

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              V +++   SW  P  +GGA + GY +   +  K  W +V  + VN     ++ L E  
Sbjct: 2165 SDVFADMCRLSWNPPADNGGAEVTGYVVEKCEDGKDFWEKVPGL-VNGTAHPVKGLKEGK 2223

Query: 2036 TYMIRIYARNEIGLSEPLESDE 2057
             Y  R+ A N+ G   PLE+D+
Sbjct: 2224 KYKFRVKAENKYGAGAPLETDK 2245



 Score =  275 bits (674), Expect = 1e-71
 Identities = 309/1257 (24%), Positives = 515/1257 (40%), Gaps = 94/1257 (7%)

Query: 864  ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            + W++N  EI +  +   +N D     LV+ NV  E D G Y    +    KS     V 
Sbjct: 1128 VKWFKNKLEIFAGHKYHFEN-DNMKYRLVVNNVKLE-DGGKYTLELNGV--KSGAWLYVE 1183

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR-EIIQEGR 980
                 V F + L + +   + K V LEC  S      KW+ N + I     + EI +   
Sbjct: 1184 AKAPHVEFTQKLPEKFSQTKRKEVDLECFVSDPRARVKWFKNGQPIEYQSGKMEIQRREN 1243

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                        D     C   D +T+    V +   +F++ L D E  E+D A  E ++
Sbjct: 1244 RCILRIKDCQPDDEAEYTCTCGDAKTTCQFKVTDPEWDFMKLLDDVEGIERDRATFECDV 1303

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
            N   A+V W R+ + +     KY+ +  G  R+L ++N    D+G Y+C + D+  TA +
Sbjct: 1304 NDPEAEVKWSRNDKELT-SGGKYEIQVDGFKRRLVVKNCHSKDDGPYTCKVLDKETTANL 1362

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSN-HIQLTIDG 1158
              VE   +   +L+N++  +      E + +   +  V+W KDG  I   +  +++T  G
Sbjct: 1363 -FVEPDVKFFKKLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKG 1421

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDA 1214
            +  K+ I +   +DAG+Y+C+VG       + V+E    P IN    +PE I+V      
Sbjct: 1422 ELYKIVIKNLTREDAGQYACQVGERSSKWEVIVDELPKPPQIN-AKDIPEEIIVKKGE-- 1478

Query: 1215 YLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
             + + IP   + +    W K  + + + +    ++D    ++ I      D  +Y   L 
Sbjct: 1479 VIEIGIPFIGVPMPSGHWKKDGNPLSEADTDIRMTDTLA-SIRIPDAQRGDTGQYELTL- 1536

Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT-LLVDYQA--FPQPNDEWIVNSK-I 1327
                T ++  EV+  P +++D     R     DV  +  D  A  + +P D+     K  
Sbjct: 1537 ----TNEVGSEVIPIPVRVLDVPG--RPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHY 1590

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGI-------YKLRLENNCGH-----ADVEMNV 1375
            I + K ++   D      T + +E    G+       +++R  N  G      AD E+  
Sbjct: 1591 IVEMKDSEKDSDRFEQVCTTEDLEVDVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIA 1650

Query: 1376 TILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434
                 PS PP   N+ + D   + I W  P + G + I  YV+E  E    EW+    + 
Sbjct: 1651 KDPWDPSDPPQDTNVEDYDKDYVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVP 1710

Query: 1435 --KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNI 1491
              K   ++  L  N  Y FR  AVN+   S+ SE T    + K  +++   + K  LK I
Sbjct: 1711 GDKRAGTVSGLTENREYIFRVSAVNKAGKSEPSEATPPV-LTKSRRVRPRIMNKDDLKPI 1769

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDG--KKLKTAKAT--------YENRXXXXXXXXX 1541
              +  +D  +   + G P PK+ W + G  KK +  + +         E +         
Sbjct: 1770 RVKVGKDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPS 1829

Query: 1542 XXXXXXYKCIAFNDHG----EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
                  Y     N HG    +VE   V+G    P   I   +I  +     EW     + 
Sbjct: 1830 RKDTAMYNVTVTNKHGSDTADVEV-VVLGPPSMPKGPIKVSNITAESATL-EWGEPEDLG 1887

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            G P   +  YK   K++  K      +E  K + + + +LK     K+ + A +  G S 
Sbjct: 1888 GSP---IDGYKV-EKMDTKKGQWEPVREGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSE 1943

Query: 1656 -VE----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
             +E    +  K YD+P  P  P  + +  R  + ++W+PP +DGG  +  Y +E+ EP  
Sbjct: 1944 PLETKPIIAKKPYDEPFPPGQPKCV-DRDRTHIKMKWEPPENDGGYPVNSYDVERKEPKT 2002

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS- 1768
            NRW K+         Y   K+ +  EY +RV+A N  G SE ++ S+ I  K   + P  
Sbjct: 2003 NRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKV 2062

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827
                      I  ++      P   +G  +P + ++   +    + K           + 
Sbjct: 2063 SLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAKCTSSEEDAKLHVD 2122

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKW 1886
            K     T ++ I   NE G+    ++D  + +   L  P  P     VS+  +    L W
Sbjct: 2123 KAERGDTGKYTITVTNESGS---MSADVNVIV---LDKPGAPEGPLAVSDVFADMCRLSW 2176

Query: 1887 TEPESNGGSPITNYIIEFKTVKGKS-WTKIV-TVGGSVHEHCIENIKEKDEIIFRISAEN 1944
              P  NGG+ +T Y++E K   GK  W K+   V G+ H   ++ +KE  +  FR+ AEN
Sbjct: 2177 NPPADNGGAEVTGYVVE-KCEDGKDFWEKVPGLVNGTAHP--VKGLKEGKKYKFRVKAEN 2233

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
              G   P E+    L K+          LEI     N     W  P++DGGA + GY + 
Sbjct: 2234 KYGAGAPLETDKSILAKNPFDTPDAPKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIVE 2293

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             R      W+ V    +   KF+   L E      R+ A N+    +P +S +P  V
Sbjct: 2294 KRPKGGD-WVPVNNFPLADTKFSALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTV 2349



 Score =  248 bits (607), Expect = 1e-63
 Identities = 248/992 (25%), Positives = 395/992 (39%), Gaps = 62/992 (6%)

Query: 1104 ELPPEIITRLQNQKVNKGNK-ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            E P + I  L + K  +G+K A FE E  K +A V+WFK+  EI   +      D  K +
Sbjct: 1094 EKPDKYIVELDDVKATEGDKKAIFESEFCKKNAKVKWFKNKLEIFAGHKYHFENDNMKYR 1153

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEI 1220
            L + +  L+D G+Y+ E+   K  A L VE   P + FT +LPE        +  L   +
Sbjct: 1154 LVVNNVKLEDGGKYTLELNGVKSGAWLYVEAKAPHVEFTQKLPEKFSQTKRKEVDLECFV 1213

Query: 1221 PDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
             D    V W+K    IE  + K  +     +  L I+ C  DD+ EYTC   DAK+T + 
Sbjct: 1214 SDPRARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTCGDAKTTCQF 1273

Query: 1280 KVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
            KV   E+   K++D        R +    + D    P+   +W  N K +      +  +
Sbjct: 1274 KVTDPEWDFMKLLDDVEGIERDRATFECDVND----PEAEVKWSRNDKELTSGGKYEIQV 1329

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
            D     L +K   + D G Y       C   D E    +  +P           D     
Sbjct: 1330 DGFKRRLVVKNCHSKDDGPY------TCKVLDKETTANLFVEP-----------DVKFFK 1372

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
               ++ E    + ++            +W+   + I K    ++  +    Y+     + 
Sbjct: 1373 KLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLT 1432

Query: 1458 EVDISD----ASETTEYYKVIKETKIQSPTVE-KPL-KNITTEPNEDIELTCIFGGVPQP 1511
              D         E +  ++VI +   + P +  K + + I  +  E IE+   F GVP P
Sbjct: 1433 REDAGQYACQVGERSSKWEVIVDELPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMP 1492

Query: 1512 KVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
               W +DG  L  A       +                 Y+    N+ G       V + 
Sbjct: 1493 SGHWKKDGNPLSEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVGSEVIPIPVRVL 1552

Query: 1569 QKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
              P       D+      K    W       G P    I     ++ ++D+   + T E 
Sbjct: 1553 DVPGRPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQVCTTED 1612

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSV-----EVTLKVYDKPSKPEGPVIMREISRE 1681
              V  +  LK  H  ++ + A N  GTS       E+  K    PS P     + +  ++
Sbjct: 1613 LEV-DVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIAKDPWDPSDPPQDTNVEDYDKD 1671

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
             V I WKPP+ DGG  + KY IEK E     W+   +V  D     +  L EN EY+FRV
Sbjct: 1672 YVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVPGDKRAGTVSGLTENREYIFRV 1731

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG-SPII 1800
             A N  G SE  E+ P V+  +  V            I  +       P E  G  +P I
Sbjct: 1732 SAVNKAGKSEPSEATPPVLTKSRRVRPRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKI 1791

Query: 1801 DYK---VEIKQEGKKWKXXXXXXXXXARIQKL-----SINTTYQFRIYARNEIGTSLPYT 1852
            ++K   ++ K+E  +            +   L     S   T  + +   N+ G+    T
Sbjct: 1792 EWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSRKDTAMYNVTVTNKHGSD---T 1848

Query: 1853 SDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
            +D ++ +   L PPS P+  + VS  T+ S TL+W EPE  GGSPI  Y +E    K   
Sbjct: 1849 ADVEVVV---LGPPSMPKGPIKVSNITAESATLEWGEPEDLGGSPIDGYKVEKMDTKKGQ 1905

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971
            W   V  G    +  +  +KE  E  FR++A +  G S P E++ +  +K    P PP  
Sbjct: 1906 WEP-VREGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSEPLETKPIIAKKPYDEPFPPGQ 1964

Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031
            P  +    ++I M  W  PE DGG P+  Y++  ++     W ++ K  + T +++   +
Sbjct: 1965 PKCVDRDRTHIKM-KWEPPENDGGYPVNSYDVERKEPKTNRWAKINKEPITTCEYDDNKV 2023

Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             +   Y  R+ A N+ G SEP  + +  +  P
Sbjct: 2024 GKEKEYEYRVVAINDAGPSEPSVASKVIQAKP 2055



 Score =  237 bits (579), Expect = 3e-60
 Identities = 191/705 (27%), Positives = 305/705 (43%), Gaps = 32/705 (4%)

Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS----IDSK 1341
            P+I++ +  +  R+K G D T+ V+Y   P P  EW     + KK +  +PS    ID+K
Sbjct: 1758 PRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKIEW-KKKGLDKKEEPLEPSDHISIDNK 1816

Query: 1342 S---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397
            +   ++LT K+    D  +Y + + N  G    ++ V +L  PS P  P  +  I + S 
Sbjct: 1817 TEKKSTLTCKEPSRKDTAMYNVTVTNKHGSDTADVEVVVLGPPSMPKGPIKVSNITAESA 1876

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456
             + W EPE+ G S I  Y VE  +    +W  V+   K T+ ++  LK    Y+FR  A+
Sbjct: 1877 TLEWGEPEDLGGSPIDGYKVEKMDTKKGQWEPVREGVKGTKVTVPKLKEGQEYKFRVAAM 1936

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            ++   S+  ET          +   P   K +    T      E     GG P       
Sbjct: 1937 SQNGNSEPLETKPIIAKKPYDEPFPPGQPKCVDRDRTHIKMKWEPPENDGGYPVNSYDVE 1996

Query: 1517 R-DGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKP- 1571
            R + K  + AK   E                   Y+ +A ND G  E S     IQ KP 
Sbjct: 1997 RKEPKTNRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPE 2056

Query: 1572 --VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
                 +S + +    + + K G+   +   + G P P V W KNG  ++N  +   T+ E
Sbjct: 2057 KEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAK--CTSSE 2114

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            + + + + + +R  + KYTI  +N +G+ S +V + V DKP  PEGP+ + ++  +   +
Sbjct: 2115 EDAKLHVDKAERGDTGKYTITVTNESGSMSADVNVIVLDKPGAPEGPLAVSDVFADMCRL 2174

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
             W PP D+GG E+T Y +EK E   + W KV  +      + ++ L E  +Y FRV A+N
Sbjct: 2175 SWNPPADNGGAEVTGYVVEKCEDGKDFWEKVPGLVNGT-AHPVKGLKEGKKYKFRVKAEN 2233

Query: 1746 PVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
              G    LE++  I+ K   D P            D  S  + W   + +GG+ I  Y V
Sbjct: 2234 KYGAGAPLETDKSILAKNPFDTPD-APKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIV 2292

Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
            E + +G  W           +   L +      +FR+ A N+  T  P  S    T+   
Sbjct: 2293 EKRPKGGDWVPVNNFPLADTKFSALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTVKDP 2352

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            +     P    + + T  S  L WT+P  +GG  I  Y IE K   G  W     V  + 
Sbjct: 2353 IFAAGAPGTPNLDKITPNSAELSWTKPTKDGGGKILGYFIEKKKGHG-DWETATEVPANA 2411

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
                + ++ E ++  FRI A N  G   P++ +Q++  E  A  P
Sbjct: 2412 LHGKVNDLVEGEQYQFRIRAINEAGPGDPSKPTQAITAEYQAEKP 2456



 Score =  219 bits (535), Expect = 7e-55
 Identities = 180/699 (25%), Positives = 300/699 (42%), Gaps = 35/699 (5%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++  +K+G    + V Y+A+ +P+  W ++ + +         ++ ++  LT  K +  D
Sbjct: 2464 KDITVKQGQKYQIRVPYKAWLKPSALWTIDEEELPSVARIHTKVEDEAVMLTNDKSQRAD 2523

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTII 1413
            +G YK+ L N  G+    +NV +L  P+ P  P    +I+   + + W  P++ G   I 
Sbjct: 2524 SGKYKITLTNPSGNHSGFVNVNVLSPPAKPEGPFTASDINGDELTLSWGAPKDDGGEKIS 2583

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             Y++E ++  + +W  V    K  T  ++NL+  + Y FR  A N   IS   ET +   
Sbjct: 2584 NYIIERKKKGSPKWSKVTGTAKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDK--A 2641

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNED-IELTCI-----FGGVPQPKVTWYRDGKKLKTAK 1526
            ++ +    +P      K +  E  ED I LT        G + +  V   ++  K    K
Sbjct: 2642 ILAKLPYDTPGAPGTPKCL--EYTEDSITLTWTPPKNDGGNIIKGYVVEKKEKGKPDWTK 2699

Query: 1527 ATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGE---VETSCVVGIQQKPVITISNEDIK 1581
            A   +                Y  +  A N+ G     +TS  +  +  PV    ++   
Sbjct: 2700 ANISDILTNEFQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFT 2759

Query: 1582 QKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKR 1637
             +    KVG+ + +     G P P+  W      L E D+     T  +  ++  K  K 
Sbjct: 2760 PRDVIAKVGEPFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKE 2819

Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
              + +YT+   N  G  ++ + + V DKPSKPEGP+   +++ +S T+ W  P DDGG  
Sbjct: 2820 D-AGRYTLTMKNEKGQDTIALNVVVVDKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSP 2878

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-E 1756
            ++ Y +EK +    RW  V+   R  + Y +  L+E  EY FRV A+N  G SE LE  E
Sbjct: 2879 VSNYVVEKCDTRTGRWEPVSKFVRGAK-YEVMGLDEGHEYKFRVSAENENGVSEPLEVLE 2937

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815
            P++ +     P           +D +SV + +     +GG  I  Y VE K     +WK 
Sbjct: 2938 PVLAQHPYTAPGSPSNVHVLD-VDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKM 2996

Query: 1816 XXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR--N 1871
                     +  +  L  +  Y+FR+ A+N  G   P    D I      T    P    
Sbjct: 2997 HNDIASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKPKYTLSGAPGVPT 3056

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVTVGGSVHEHCIENI 1930
            F V ++    V LKW +P ++GG+ I  YI+E K  KG   W K+     S   + +  +
Sbjct: 3057 FTVGKTF---VDLKWDKPRNDGGAKIKGYIVE-KRAKGSDVWVKVNDYPVSDCGYTVNGL 3112

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969
             E  E  FR+ A N  G   P+ +  +   K   V + P
Sbjct: 3113 PEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAP 3151



 Score =  201 bits (491), Expect = 1e-49
 Identities = 224/935 (23%), Positives = 388/935 (41%), Gaps = 54/935 (5%)

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDAYL 1216
            GK+++ +     ++DAG     V +    A    E P ++   L     I V A     +
Sbjct: 2024 GKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDI 2083

Query: 1217 TVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
             V +    T  V+W K    +++  K T  S  +   L + K    D  +YT  + +   
Sbjct: 2084 PVGVSGTPTPTVSWEKNGRPVDNRAKCT--SSEEDAKLHVDKAERGDTGKYTITVTNESG 2141

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKH 1333
            +    V V+    K    E    +   SDV   +   ++  P D     V   +++KC+ 
Sbjct: 2142 SMSADVNVIVLD-KPGAPEGPLAV---SDVFADMCRLSWNPPADNGGAEVTGYVVEKCED 2197

Query: 1334 TK------PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTILDKP--SPP 1384
             K      P + + +A   +K ++      ++++ EN  G  A +E + +IL K     P
Sbjct: 2198 GKDFWEKVPGLVNGTAH-PVKGLKEGKKYKFRVKAENKYGAGAPLETDKSILAKNPFDTP 2256

Query: 1385 GKPNILEIDSSSINIC---WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTS 1439
              P  LEID    N C   W +P+  G + I  Y+VE +     +W+ V N  +  T+ S
Sbjct: 2257 DAPKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIVEKRP-KGGDWVPVNNFPLADTKFS 2315

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
               LK     +FR  AVN+      S++T+ + V K+    +     P  +  T  + ++
Sbjct: 2316 ALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTV-KDPIFAAGAPGTPNLDKITPNSAEL 2374

Query: 1500 ELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
              T          + ++ + KK     +TA     N                ++  A N+
Sbjct: 2375 SWTKPTKDGGGKILGYFIEKKKGHGDWETATEVPANALHGKVNDLVEGEQYQFRIRAINE 2434

Query: 1556 HGEVE----TSCVVGIQQ--KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
             G  +    T  +    Q  KP + +S  +DI  K   G ++ +    +    P  +W  
Sbjct: 2435 AGPGDPSKPTQAITAEYQAEKPHLDLSGIKDITVKQ--GQKYQIRVPYKAWLKPSALWTI 2492

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            +  +L +    +   +++  ++   + +R+ S KY I  +N +G  S  V + V   P+K
Sbjct: 2493 DEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPSGNHSGFVNVNVLSPPAK 2552

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            PEGP    +I+ + +T+ W  P DDGG +++ Y IE+ +  + +W KV    ++  T  +
Sbjct: 2553 PEGPFTASDINGDELTLSWGAPKDDGGEKISNYIIERKKKGSPKWSKVTGTAKE-PTCQV 2611

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
            + L    EY FRV+A+N  G S  LE++  I+ K   D P            + +S+ +T
Sbjct: 2612 RNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDTPGAPGTPKCLEYTE-DSITLT 2670

Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGK-KWKXX--XXXXXXXARIQKLSINTTYQFRIYARNE 1844
            W P + +GG+ I  Y VE K++GK  W             +++ L     Y+FR+ ARN 
Sbjct: 2671 WTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNEFQVKGLQEGKEYEFRVAARNN 2730

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR-SVTLKWTEPESNGGSPITNYIIE 1903
             G      +   I        P   ++F   +  ++     K   P +    P TN+ I 
Sbjct: 2731 AGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAKVGEPFKIVIPYNGNPIPDTNWSIG 2790

Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
             + +      K       + +   +   ++D   + ++ +N  G         V ++K  
Sbjct: 2791 TRDLFEGDRIKFENTPNEL-KLLNKKATKEDAGRYTLTMKNEKGQD-TIALNVVVVDK-- 2846

Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
              PS P  PLE   V  +    +W  P+ DGG+P+  Y +   D     W  V K  V  
Sbjct: 2847 --PSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVSNYVVEKCDTRTGRWEPVSKF-VRG 2903

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             K+ +  L E H Y  R+ A NE G+SEPLE  EP
Sbjct: 2904 AKYEVMGLDEGHEYKFRVSAENENGVSEPLEVLEP 2938



 Score =  182 bits (443), Expect = 1e-43
 Identities = 126/487 (25%), Positives = 212/487 (43%), Gaps = 16/487 (3%)

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQ 1441
            PG P    +  + +++ WD+P N G + I  Y+VE +   +  W+ V +  ++    ++ 
Sbjct: 3052 PGVPTFT-VGKTFVDLKWDKPRNDGGAKIKGYIVEKRAKGSDVWVKVNDYPVSDCGYTVN 3110

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIE 1500
             L     + FR  AVN+    + S TT   K+ ++    +P   K L      P   ++ 
Sbjct: 3111 GLPEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMI 3170

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
             +    G P P VTWY++G  + +   T     ++                 KC   N  
Sbjct: 3171 FSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPL 3230

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G    +C   IQ  P       D  Q+ ++G+++ +     G  P EV   KNG ++  +
Sbjct: 3231 GRDSCTCNFKIQSPPKFGKDFHD--QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQN 3288

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
                I   +    + I +     + +Y +E SN  G + +   LKV   P KP GP+ + 
Sbjct: 3289 GRIKIMPFDDYVSLTINDANLDDAGQYKVEVSNAGGAAELGFGLKVVGAPEKPTGPLGVS 3348

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
            +I++ +  ++WKPP  DGG ++T Y +E+ E     W+ V+   +D     +Q L +N  
Sbjct: 3349 DITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRCKDC-NQDVQGLYDNYL 3407

Query: 1737 YMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            Y FRV A N  G SE L +E PI+ K   D P           + ++ V +TW   + +G
Sbjct: 3408 YAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPD-APGVPEITEVGSDFVSLTWEKPKHDG 3466

Query: 1796 GSPIIDYKVEIKQEG-KKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
            G  I  Y ++ ++ G   W              I KL  +  Y+FR++A NE G S P  
Sbjct: 3467 GGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYEFRVFAENEAGMSKPSM 3526

Query: 1853 SDDKITI 1859
            +   + I
Sbjct: 3527 NSQAVKI 3533



 Score =  177 bits (430), Expect = 4e-42
 Identities = 112/393 (28%), Positives = 185/393 (47%), Gaps = 16/393 (4%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            DKP  PG P I E+ S  +++ W++P++ G   I  Y ++ +E  T  W  V N+    T
Sbjct: 3437 DKPDAPGVPEITEVGSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRV-NLQPCIT 3495

Query: 1439 SIQNLKT---NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
            +I N+     +  Y FR +A NE  +S  S  ++  K+        P     L+    + 
Sbjct: 3496 NIINIPKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDPKAAVIPEFSSGLRKCHAQQ 3555

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE--NRXXXXXXXXXXXXXXXYKCI 1551
             +  +  C   G P P + W++  +++ ++     Y   ++               Y C 
Sbjct: 3556 GKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCR 3615

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISN--EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            A N  G   +   + I   P IT+    +D+    K G+  ++     G P P + W  +
Sbjct: 3616 ASNHGGSRTSRANLEISSPPKITVPKRFQDVAIFEK-GESAVMKIPFTGNPKPTITWMHD 3674

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            G +++  + Y+    E+ +++ IK+  +     Y I A N  G+ S  + +++ D+P  P
Sbjct: 3675 GEEVKG-RNYHSEVTERHAILTIKDANKDQDGPYRITAKNDLGSDSAVIKIQINDRPDPP 3733

Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
              P     I  ESV + WKPPL+DGG  +T+Y IEK EP N  WI+VA V R +  + I 
Sbjct: 3734 RYPTC-ENIRDESVLLSWKPPLNDGGSFITQYIIEKCEPPNTNWIRVA-VSR-MCFHNIT 3790

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
             L+ N EY FRV+A+N  G S+  +    VIKT
Sbjct: 3791 SLSANKEYQFRVVAENFYGKSDPCD-PTAVIKT 3822



 Score =  173 bits (422), Expect = 3e-41
 Identities = 165/705 (23%), Positives = 281/705 (39%), Gaps = 44/705 (6%)

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT--SIQ 1441
            PG PN+ +I  +S  + W +P   G   I+ Y +E ++    +W +   +        + 
Sbjct: 2359 PGTPNLDKITPNSAELSWTKPTKDGGGKILGYFIEKKK-GHGDWETATEVPANALHGKVN 2417

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIE 1500
            +L     Y+FR  A+NE    D S+ T+   +  E + + P ++   +K+IT +  +  +
Sbjct: 2418 DLVEGEQYQFRIRAINEAGPGDPSKPTQ--AITAEYQAEKPHLDLSGIKDITVKQGQKYQ 2475

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFN-- 1554
            +   +    +P   W  D ++L +    +    +                 YK    N  
Sbjct: 2476 IRVPYKAWLKPSALWTIDEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPS 2535

Query: 1555 -DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI--WYKNGN 1611
             +H       V+    KP    +  DI      GDE  ++         E I  +     
Sbjct: 2536 GNHSGFVNVNVLSPPAKPEGPFTASDIN-----GDELTLSWGAPKDDGGEKISNYIIERK 2590

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV------YDK 1665
            K  + K   +T   K    +++ L+     ++ + A N  G S+   T K       YD 
Sbjct: 2591 KKGSPKWSKVTGTAKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDT 2650

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P  P  P  + E + +S+T+ W PP +DGG  +  Y +EK E     W K    D     
Sbjct: 2651 PGAPGTPKCL-EYTEDSITLTWTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNE 2709

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
            + ++ L E  EY FRV A+N  G  + A  S+ I  + A   P           I     
Sbjct: 2710 FQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAKVGE 2769

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
                         P  ++ +  +   EG + K            +K +     ++ +  +
Sbjct: 2770 PFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKEDAGRYTLTMK 2829

Query: 1843 NEIGTSLPYTSDDKITIGKTLTP-PSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            NE G        D I +   +   PS+P       + T  S TL W +P+ +GGSP++NY
Sbjct: 2830 NEKG-------QDTIALNVVVVDKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVSNY 2882

Query: 1901 IIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
            ++E    +   W  +   V G+ +E  +  + E  E  FR+SAEN  GVS P E     L
Sbjct: 2883 VVEKCDTRTGRWEPVSKFVRGAKYE--VMGLDEGHEYKFRVSAENENGVSEPLEVLEPVL 2940

Query: 1960 EKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
             +H  T P  P + + +  V  + V  ++  P  DGG  + GY +  +D T   W     
Sbjct: 2941 AQHPYTAPGSP-SNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKMHND 2999

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            +    LK+ +  L ++  Y  R+ A+N  GL EP +  +  +  P
Sbjct: 3000 IASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKP 3044



 Score =  144 bits (349), Expect = 2e-32
 Identities = 130/501 (25%), Positives = 219/501 (43%), Gaps = 43/501 (8%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            G+P P   W K+GN L ++ + +I   +  + IRI + +R  + +Y +  +N  G+  + 
Sbjct: 1488 GVPMPSGHWKKDGNPL-SEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVGSEVIP 1546

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE--KHEPDNNRWIK 1715
            + ++V D P +P  P+ + ++  +   + W  P DDGG  +  Y +E    E D++R+ +
Sbjct: 1547 IPVRVLDVPGRPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQ 1606

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXX 1774
            V   + D+E   +  L E   Y FRV A N  G SE L ++  I+ K   D PS      
Sbjct: 1607 VCTTE-DLEV-DVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIAKDPWD-PSDPPQDT 1663

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW--KXXXXXXXXXARIQKLSI 1831
                 D + V I W P   +GG+PI  Y +E  ++   +W              +  L+ 
Sbjct: 1664 NVEDYDKDYVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVPGDKRAGTVSGLTE 1723

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK----WT 1887
            N  Y FR+ A N+ G S P  +   +     LT   + R  ++++   + + +K    +T
Sbjct: 1724 NREYIFRVSAVNKAGKSEPSEATPPV-----LTKSRRVRPRIMNKDDLKPIRVKVGKDFT 1778

Query: 1888 EPESNGGSPITNYIIEFKTVKGKSW----TKIVTVGGSVHEHCIENIKE---KDEIIFRI 1940
             P    G P      + K +  K      +  +++     +      KE   KD  ++ +
Sbjct: 1779 IPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSRKDTAMYNV 1838

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            +  N  G S   + + V L      PS P  P+++  + +      WG PE  GG+P+ G
Sbjct: 1839 TVTNKHG-SDTADVEVVVLGP----PSMPKGPIKVSNITAESATLEWGEPEDLGGSPIDG 1893

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES----- 2055
            Y +   D  K  W  V +  V   K  +  L E   Y  R+ A ++ G SEPLE+     
Sbjct: 1894 YKVEKMDTKKGQWEPV-REGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSEPLETKPIIA 1952

Query: 2056 ----DEPFKVIPGEGSHADEE 2072
                DEPF   PG+    D +
Sbjct: 1953 KKPYDEPFP--PGQPKCVDRD 1971



 Score =  140 bits (340), Expect = 3e-31
 Identities = 119/444 (26%), Positives = 198/444 (44%), Gaps = 51/444 (11%)

Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD---DDN 564
           +AP F +K   K   +G  + F+C +E  P+P I WF+ T  +  S   +M  +    +N
Sbjct: 7   IAPRFTQKPVLKQEDNGKLLVFQCTLEAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGGNN 66

Query: 565 VATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
              ++ I+ V   DAGT+  VAKN  G  S++  L   AP    G +             
Sbjct: 67  YNVMMDIKGVTQADAGTYKVVAKNKLGEVSASINLNFSAP----GQKQQ----------- 111

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                 +GI P F++KP  +  D G + I LEC+L A P P I+W    ++I     I +
Sbjct: 112 ------DGIAPNFTQKPSTRQADNGKETICLECQLTADPVPQISWFRDDQQIKDGGRIKI 165

Query: 683 AIE-SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP- 740
             +    + Y  VL+I  V     G Y V A N  GE++  I L   + +K  PQ   P 
Sbjct: 166 QTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNALGESNATIRLNFDSDDKGKPQGTRPS 225

Query: 741 --LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALPTKSDGDTHSITIL 792
              K  I + G  +I   +V  +P+PTITW K  + +      K + T  D + + ++++
Sbjct: 226 FTTKPAIKQVGGKIIFDCKVTADPKPTITWMKGTQALTDGGRYKMIQT-GDKNNYDVSMV 284

Query: 793 KPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENA---EPPLFINRFQEITVKEKG 848
             K  KD+ G Y   A+NS G +  +  +  E    + A   + P F+ +   +  +EK 
Sbjct: 285 IDKPGKDDGGEYKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQFLAK--PVVKQEKT 342

Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE----TITQNFDGENIELVITNV--DSEIDSG 902
            + +   +   P P+I W++    +         +T +    +      N+      D G
Sbjct: 343 NLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATLNIKDPKPTDGG 402

Query: 903 DYKCVASNSAGKSSHGARVTIDVE 926
            +KC ASN  G+S+  A +T++ +
Sbjct: 403 SFKCTASNDFGESN--ANITLNFQ 424



 Score =  138 bits (333), Expect = 2e-30
 Identities = 178/750 (23%), Positives = 299/750 (39%), Gaps = 54/750 (7%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            L+ +K T++D   YT  + + K   T  L V VV+ P K      E  ++   DVT    
Sbjct: 2811 LLNKKATKEDAGRYTLTMKNEKGQDTIALNVVVVDKPSK-----PEGPLEC-IDVTPDSC 2864

Query: 1311 YQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIKKVE--NTDAGI-YKLRL--E 1363
               + +P D+    V++ +++KC       +  S  +   K E    D G  YK R+  E
Sbjct: 2865 TLTWNKPKDDGGSPVSNYVVEKCDTRTGRWEPVSKFVRGAKYEVMGLDEGHEYKFRVSAE 2924

Query: 1364 NNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            N  G ++ +E+   +L +     P  P   ++L++D  S+ + ++ P + G   I  Y V
Sbjct: 2925 NENGVSEPLEVLEPVLAQHPYTAPGSPSNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCV 2984

Query: 1418 EYQEIDTTEWISVKNITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI- 1474
            EY++  +  W    +I       ++  LK +  Y FR  A N   + + S+ T+  +   
Sbjct: 2985 EYKDPTSGRWKMHNDIASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKP 3044

Query: 1475 KETKIQSP-----TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
            K T   +P     TV K   ++  +   +     I G + + +      G  +      Y
Sbjct: 3045 KYTLSGAPGVPTFTVGKTFVDLKWDKPRNDGGAKIKGYIVEKRAK----GSDVWVKVNDY 3100

Query: 1530 E-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHK- 1585
              +                ++  A N  GE E S   G+ +  + V+  + E IK+ H  
Sbjct: 3101 PVSDCGYTVNGLPEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAPEFIKKLHPT 3160

Query: 1586 ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                +G E + +  + G P P+V WYKNG  + +     +T  +    +R  EL  +   
Sbjct: 3161 EMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEG 3220

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
            +   + SN  G  S     K+   P   +     +    E   I  K P    G    K 
Sbjct: 3221 EIKCDISNPLGRDSCTCNFKIQSPPKFGKDFHDQQVELGEQFKI--KIPFSGTGPFEVKV 3278

Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
                 E   N  IK+   D D  +  I   N +    ++V   N  G +E      +V  
Sbjct: 3279 RKNGREVVQNGRIKIMPFD-DYVSLTINDANLDDAGQYKVEVSNAGGAAELGFGLKVV-- 3335

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821
                 P           I   +  + W P + +GGS I  Y VE ++ GK +        
Sbjct: 3336 ---GAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRC 3392

Query: 1822 XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                  +Q L  N  Y FR+ A NE G S P T++  I        P  P    ++E  S
Sbjct: 3393 KDCNQDVQGLYDNYLYAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPDAPGVPEITEVGS 3452

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
              V+L W +P+ +GG  I  Y I+ +     +W+++       +   I  + E     FR
Sbjct: 3453 DFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYEFR 3512

Query: 1940 ISAENTVGVSLPT-ESQSVRLE--KHATVP 1966
            + AEN  G+S P+  SQ+V+++  K A +P
Sbjct: 3513 VFAENEAGMSKPSMNSQAVKIKDPKAAVIP 3542



 Score =  119 bits (287), Expect = 8e-25
 Identities = 108/443 (24%), Positives = 180/443 (40%), Gaps = 31/443 (6%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD---- 561
           +  AP F+ K  P    + + +   C +E  P+P I WF+ T  +K    + +       
Sbjct: 325 EGKAPQFLAK--PVVKQEKTNLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPG 382

Query: 562 --DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE---MTVXX 615
             D   ATL I++  P D G+F C A N  G +++   L  + A   D  SE        
Sbjct: 383 KADSYTATLNIKDPKPTDGGSFKCTASNDFGESNANITLNFQGAEQKDKPSEDQEKPAAP 442

Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
                          G  PTF+KKP  +   EG ++++ C+  A P+P  +W   G  + 
Sbjct: 443 KPAEKKNKPAPAKPAGTAPTFTKKPVIK--QEGKNLIVHCKCKANPKPTFSWYKSGLPLK 500

Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--E 733
               I   ++     Y + L + NV K     Y VVA N  GE +  I + +    K  E
Sbjct: 501 ETFRIKTRVDGKGDDYDTFLDLINVTKNDAAEYKVVAKNAHGEGNATITVNMDEPPKAAE 560

Query: 734 PPQVIEPLKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTH 787
           PP   + L  + + + G+ + ++ +V    +PT  W   NKP+K      L    D D +
Sbjct: 561 PPPQFQGLPQVTLEEGGKRLCITQKVKCKTKPTAMWYFLNKPIKHGGKYFLEISQDRDCY 620

Query: 788 SIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-----EPTEENAEPPLFINRFQ 840
           ++   +L PK++ D G Y    +   G  E SA + ++     +P      PP    +  
Sbjct: 621 NVVCEVLNPKEL-DSGEYKFSIKTPGGEGEGSARVDLKALMAPKPKVPKGSPPSSTQKLA 679

Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
              V +     L+A+V  N    +   ++ + +  S+     F      L I  V  + D
Sbjct: 680 PTEVLDGDACDLIAKVAGNEPIEVVCSKDGDKLKHSKDCQITFKDNVCRLYIPEVYPD-D 738

Query: 901 SGDYKCVASNSAGKSSHGARVTI 923
            G Y+    N  GK+   A + +
Sbjct: 739 GGKYQIDLENEFGKAMTSATLVV 761



 Score =  119 bits (287), Expect = 8e-25
 Identities = 96/435 (22%), Positives = 176/435 (40%), Gaps = 17/435 (3%)

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTI 1685
            T+  ++K L+     ++ + A N AG      T +     + P  P + +  + R+ +  
Sbjct: 2707 TNEFQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAK 2766

Query: 1686 EWKP-----PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
              +P     P +   +  T ++I   +      IK  +   +++    +   E+    + 
Sbjct: 2767 VGEPFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKEDAG-RYT 2825

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            +  +N  G  + +    +V+    D PS          +  +S  +TW   + +GGSP+ 
Sbjct: 2826 LTMKNEKG-QDTIALNVVVV----DKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVS 2880

Query: 1801 DYKVE-IKQEGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
            +Y VE       +W+            +  L     Y+FR+ A NE G S P    + + 
Sbjct: 2881 NYVVEKCDTRTGRWEPVSKFVRGAKYEVMGLDEGHEYKFRVSAENENGVSEPLEVLEPVL 2940

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
                 T P  P N  V +    SVTL +  P  +GG  I  Y +E+K      W     +
Sbjct: 2941 AQHPYTAPGSPSNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKMHNDI 3000

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977
                 ++ ++ +K+  +  FR+ A+N  G+  P++ +  +R +   T+   P  P     
Sbjct: 3001 ASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKPKYTLSGAPGVP--TFT 3058

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
            VG   V   W  P  DGGA + GY +  R     +W++V    V+   + +  L E   +
Sbjct: 3059 VGKTFVDLKWDKPRNDGGAKIKGYIVEKRAKGSDVWVKVNDYPVSDCGYTVNGLPEGGEF 3118

Query: 2038 MIRIYARNEIGLSEP 2052
              R+ A N+ G  EP
Sbjct: 3119 EFRVRAVNQAGEGEP 3133



 Score =  118 bits (284), Expect = 2e-24
 Identities = 108/442 (24%), Positives = 174/442 (39%), Gaps = 32/442 (7%)

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLK---VYDK--PSKPEGPVIMREISRESVTIEWKP 1689
            LK     K+ + A N   T     + K   V D    +   G   + +I+  S  + W  
Sbjct: 2319 LKERQVLKFRVSAVNQGSTGKPSKSTKPHTVKDPIFAAGAPGTPNLDKITPNSAELSWTK 2378

Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
            P  DGG ++  Y IEK +   + W    +V  +     +  L E  +Y FR+ A N  G 
Sbjct: 2379 PTKDGGGKILGYFIEKKKGHGD-WETATEVPANALHGKVNDLVEGEQYQFRIRAINEAGP 2437

Query: 1750 SEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
             +  + ++ I  +   + P           +     Y    P           YK  +K 
Sbjct: 2438 GDPSKPTQAITAEYQAEKPHLDLSGIKDITVKQGQKYQIRVP-----------YKAWLKP 2486

Query: 1809 EGKKWKXXXXXXXXXARIQK-------LSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
                W          ARI         +  N   Q     + +I  + P  +        
Sbjct: 2487 SAL-WTIDEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPSGNHSGFVNVN 2545

Query: 1862 TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
             L+PP++P   F  S+     +TL W  P+ +GG  I+NYIIE K      W+K+   G 
Sbjct: 2546 VLSPPAKPEGPFTASDINGDELTLSWGAPKDDGGEKISNYIIERKKKGSPKWSKVT--GT 2603

Query: 1921 SVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMV 1978
            +    C + N++   E  FR+ AEN  G+S P E+    L K     P  P  P  +   
Sbjct: 2604 AKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDTPGAPGTPKCLEYT 2663

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
              +I +T W  P+ DGG  + GY +  ++  K  W +    D+ T +F ++ L E   Y 
Sbjct: 2664 EDSITLT-WTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNEFQVKGLQEGKEYE 2722

Query: 2039 IRIYARNEIGLSEPLESDEPFK 2060
             R+ ARN  G+ +  ++ +  K
Sbjct: 2723 FRVAARNNAGVGDWAQTSQAIK 2744



 Score =  117 bits (282), Expect = 3e-24
 Identities = 174/718 (24%), Positives = 302/718 (42%), Gaps = 114/718 (15%)

Query: 476  DENNYTQYLQKKLNEKIDKLPV-FEKPTSEEQS-MAPIFVEKLRPKHTPDGS-TVQFECQ 532
            D   Y    + KL E    + + F  P  ++Q  +AP F +K   +   +G  T+  ECQ
Sbjct: 80   DAGTYKVVAKNKLGEVSASINLNFSAPGQKQQDGIAPNFTQKPSTRQADNGKETICLECQ 139

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYD----DDNVATLVIREVFPEDAGTFTCVAKNA 588
            +   P PQI+WFR    IK     ++  D    ++    L I  V  +DAG +   AKNA
Sbjct: 140  LTADPVPQISWFRDDQQIKDGGRIKIQTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNA 199

Query: 589  AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
             G +++T  L  ++   D G                     +G  P+F+ KP  + V  G
Sbjct: 200  LGESNATIRLNFDS--DDKGKP-------------------QGTRPSFTTKPAIKQV--G 236

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYCSVLKITNVKKFQEGT 707
              I+ +C++ A P+P I W+ KG + + D      I++ D + Y   + I    K   G 
Sbjct: 237  GKIIFDCKVTADPKPTITWM-KGTQALTDGGRYKMIQTGDKNNYDVSMVIDKPGKDDGGE 295

Query: 708  YTVVAVNREGEASLPIVLKIKT-GEKEPPQVIEP---LKSMIVRQGESVILSAQVVGNPR 763
            Y  +A N  G+++  I L  +  G K+ P+   P    K ++ ++  ++I++  +   P+
Sbjct: 296  YKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQFLAKPVVKQEKTNLIMTCNLEAKPQ 355

Query: 764  PTITWCKNNK--------PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIA 814
            P I W +            +K  P+    D+++ T+ +K  K  D G +   A N  G  
Sbjct: 356  PNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATLNIKDPKPTDGGSFKCTASNDFG-- 413

Query: 815  ETSAVITV--------EEPTEENAEP--PLFINR----------------FQEITVKEKG 848
            E++A IT+        ++P+E+  +P  P    +                 ++  +K++G
Sbjct: 414  ESNANITLNFQGAEQKDKPSEDQEKPAAPKPAEKKNKPAPAKPAGTAPTFTKKPVIKQEG 473

Query: 849  TIKLV-ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE----LVITNVDSEIDSGD 903
               +V  +   NP P+ +WY++   +  +  I    DG+  +    L + NV ++ D+ +
Sbjct: 474  KNLIVHCKCKANPKPTFSWYKSGLPLKETFRIKTRVDGKGDDYDTFLDLINV-TKNDAAE 532

Query: 904  YKCVASNSAGKSSHGARVTID-----VEKVTFVKHLQKSYETEEGK----TVILECQTSH 954
            YK VA N+ G+ +    V +D      E     + L +    E GK    T  ++C+T  
Sbjct: 533  YKVVAKNAHGEGNATITVNMDEPPKAAEPPPQFQGLPQVTLEEGGKRLCITQKVKCKTKP 592

Query: 955  TVSTKWYHNKKEI--SGMDHREIIQEG--RXXXXXXXXXXXXDVGVIKCIVK----DQET 1006
            T    WY   K I   G    EI Q+                D G  K  +K    + E 
Sbjct: 593  T--AMWYFLNKPIKHGGKYFLEISQDRDCYNVVCEVLNPKELDSGEYKFSIKTPGGEGEG 650

Query: 1007 STML-----------VVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054
            S  +           V K + P   +KL   EV + D   L  ++  +E  +VV  +DG+
Sbjct: 651  SARVDLKALMAPKPKVPKGSPPSSTQKLAPTEVLDGDACDLIAKVAGNEPIEVVCSKDGD 710

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEI 1109
             +K  K+      + ++ +LYI      D G+Y   L +E   + T+   VV   P++
Sbjct: 711  KLKHSKD-CQITFKDNVCRLYIPEVYPDDGGKYQIDLENEFGKAMTSATLVVSENPDM 767



 Score =  111 bits (268), Expect = 2e-22
 Identities = 85/316 (26%), Positives = 155/316 (49%), Gaps = 23/316 (7%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDM 688
           + I P F++KP  +  D G  ++ +C L A P+PDI W      +   + I + +E +  
Sbjct: 5   DDIAPRFTQKPVLKQEDNGKLLVFQCTLEAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGG 64

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKE-----PPQVIEPLK 742
           + Y  ++ I  V +   GTY VVA N+ GE S  I L     G+K+     P    +P  
Sbjct: 65  NNYNVMMDIKGVTQADAGTYKVVAKNKLGEVSASINLNFSAPGQKQQDGIAPNFTQKPST 124

Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKV 797
                  E++ L  Q+  +P P I+W ++++ +K      + T   G+ +   +L+   V
Sbjct: 125 RQADNGKETICLECQLTADPVPQISWFRDDQQIKDGGRIKIQTDPKGNNNYFIVLEINGV 184

Query: 798 --KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKE-KGTIKLV 853
             +D G Y + A+N+ G  E++A I +   +++  +P      F  +  +K+  G I   
Sbjct: 185 NAQDAGNYRVTAKNALG--ESNATIRLNFDSDDKGKPQGTRPSFTTKPAIKQVGGKIIFD 242

Query: 854 ARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIEL-VITNVDSEIDSGDYKCVASN 910
            +VT +P P+ITW +  + ++      + Q  D  N ++ ++ +   + D G+YKC+A N
Sbjct: 243 CKVTADPKPTITWMKGTQALTDGGRYKMIQTGDKNNYDVSMVIDKPGKDDGGEYKCLAKN 302

Query: 911 SAGKSSHGARVTIDVE 926
           S G S+  A +T++ E
Sbjct: 303 SLGDST--ATITLNFE 316



 Score =  111 bits (267), Expect = 2e-22
 Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 7/260 (2%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283
            D+ W+K    I  + KF + ++  K+ LI+     +DQ EY+C   +     T++  +E+
Sbjct: 3572 DIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEI 3631

Query: 1284 VEFPPKIVDYEREYRI---KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
               PPKI   +R   +   ++G    + + +   P+P   W+ + + +K  ++    +  
Sbjct: 3632 SS-PPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEEVKG-RNYHSEVTE 3689

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
            + A LTIK       G Y++  +N+ G     + + I D+P PP  P    I   S+ + 
Sbjct: 3690 RHAILTIKDANKDQDGPYRITAKNDLGSDSAVIKIQINDRPDPPRYPTCENIRDESVLLS 3749

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            W  P N G S I  Y++E  E   T WI V        +I +L  N  Y+FR  A N   
Sbjct: 3750 WKPPLNDGGSFITQYIIEKCEPPNTNWIRVAVSRMCFHNITSLSANKEYQFRVVAENFYG 3809

Query: 1461 ISDASETTEYYKVIKETKIQ 1480
             SD  + T   K  +   I+
Sbjct: 3810 KSDPCDPTAVIKTDESDAIK 3829



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 4/203 (1%)

Query: 1861 KTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919
            K +  P +P   + VS+ T  +  L+W  P+++GGS IT+Y++E + V    W  + +  
Sbjct: 3333 KVVGAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRC 3392

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMV 1978
               ++  ++ + +     FR+SA N  G S P  +++  + K     P  P  P EI  V
Sbjct: 3393 KDCNQD-VQGLYDNYLYAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPDAPGVP-EITEV 3450

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
            GS+ V  +W  P+ DGG  + GY I  R+     W  V      T   NI  L E+  Y 
Sbjct: 3451 GSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYE 3510

Query: 2039 IRIYARNEIGLSEPLESDEPFKV 2061
             R++A NE G+S+P  + +  K+
Sbjct: 3511 FRVFAENEAGMSKPSMNSQAVKI 3533



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 110/428 (25%), Positives = 186/428 (43%), Gaps = 36/428 (8%)

Query: 1653 TSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            T+   +  K+ +DKP  P  P I  E+  + V++ W+ P  DGG  +  Y I+K E   +
Sbjct: 3425 TAETPIIAKMPFDKPDAPGVPEIT-EVGSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTD 3483

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT--ALDVPS 1768
             W +V           I KL E+  Y FRV A+N  G S+ ++ S+ + IK   A  +P 
Sbjct: 3484 NWSRVNLQPCITNIINIPKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDPKAAVIPE 3543

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXAR 1825
                         +S     F  E +G  SP I +    ++     K++           
Sbjct: 3544 FSSGLRKCHAQQGKSAK---FECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLI 3600

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            +  +      ++   A N  G S    ++ +I+    +T P + ++  + E    S  +K
Sbjct: 3601 VHDVFGEDQDEYSCRASNH-GGSRTSRANLEISSPPKITVPKRFQDVAIFEK-GESAVMK 3658

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE--KDEI-IFRISA 1942
               P +    P   ++ + + VKG+++   VT       H I  IK+  KD+   +RI+A
Sbjct: 3659 I--PFTGNPKPTITWMHDGEEVKGRNYHSEVT-----ERHAILTIKDANKDQDGPYRITA 3711

Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
            +N +G    ++S  ++++ +   P PP  P     +    V+ SW  P  DGG+ +  Y 
Sbjct: 3712 KNDLG----SDSAVIKIQINDR-PDPPRYPT-CENIRDESVLLSWKPPLNDGGSFITQYI 3765

Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKF-NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            I   +   T W+   +V V+ + F NI  LS N  Y  R+ A N  G S+P    +P  V
Sbjct: 3766 IEKCEPPNTNWI---RVAVSRMCFHNITSLSANKEYQFRVVAENFYGKSDPC---DPTAV 3819

Query: 2062 IPGEGSHA 2069
            I  + S A
Sbjct: 3820 IKTDESDA 3827



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 68/289 (23%), Positives = 121/289 (41%), Gaps = 8/289 (2%)

Query: 1183 SKCTAILTVEEPSIN----FTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIE 1237
            S  T ++ ++E  +     F  +L    + P   +   +V++  + + DVTWYK    + 
Sbjct: 3134 SGTTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMG 3193

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE 1296
             T +  L  +    TL   +   +D+ E  C + +            ++ PPK      +
Sbjct: 3194 STSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPLGRDSCTCNFKIQSPPKFGKDFHD 3253

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
             +++ G    + + +        +   N + + +    K        SLTI      DAG
Sbjct: 3254 QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQNGRIKIMPFDDYVSLTINDANLDDAG 3313

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415
             YK+ + N  G A++   + ++  P  P  P  + +I  S+  + W  P+  G S I +Y
Sbjct: 3314 QYKVEVSNAGGAAELGFGLKVVGAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHY 3373

Query: 1416 VVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            VVE QE+    W++V +  K     +Q L  N  Y FR  AVNE   S+
Sbjct: 3374 VVERQEVGKPYWVTVSSRCKDCNQDVQGLYDNYLYAFRVSAVNEFGQSE 3422



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 89/430 (20%), Positives = 165/430 (38%), Gaps = 41/430 (9%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            + +  AP F+ K R     +G + +F+C++ G   P +TW    +++  S  +   Y   
Sbjct: 4196 DRKEAAPRFIRKPRNILAAEGQSTKFDCKIIGASPPIVTWSYDNSVLSQSVKYMQKY-RG 4254

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-------PLSDHGSEMTVXXX 616
            N   L I  +   D G +T +A+N+ G       L VE        P S   + M     
Sbjct: 4255 NEYELKISRLKMADKGLYTVIAENSFGKREEHATLKVEVNPELQRMPSSRDTTPMRRSRR 4314

Query: 617  XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP 676
                       + E    +F  +P+   +  GS+  L   + + P P + W    +++  
Sbjct: 4315 PSMSPAPEVKPVEEAPKISFGLRPR--LIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAK 4372

Query: 677  DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEP 734
            D +   +    +    + +K+ + K    GTYT  A+N   E E S  +V++ +  + + 
Sbjct: 4373 DPHYMCSYSGGV----ATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDK 4428

Query: 735  PQVIEPLK-SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
              + +  K S   R  +S    A    +   T T   + +      T +    H      
Sbjct: 4429 SDIFKSHKQSRTARTTKSGFSFADSSSSYNETSTSSSSTR------TSNRSSRH------ 4476

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
                    V     E+S   + +S      EP   + E P F  +   +++ E   +KL 
Sbjct: 4477 --------VEKSSYEDSYSSSRSSPRDKKREP---SVEAPEFTTQLSPLSLNEGDRLKLT 4525

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
              V   P P + W+ N +++   + I  +    +  L I +   + D G+Y C A N  G
Sbjct: 4526 CTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIID-DDGNYVCKAKNPGG 4584

Query: 914  KSSHGARVTI 923
            ++S    V +
Sbjct: 4585 QASSRTSVQV 4594



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 59/207 (28%), Positives = 92/207 (44%), Gaps = 18/207 (8%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYC 692
            P FS   +  +  +G     EC +   P PDI W FKG  EI       +  E D     
Sbjct: 3542 PEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRW-FKGTREIYSSPKFEIYNEGDKQ--- 3597

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM---IVRQG 749
             VL + +V    +  Y+  A N  G  +    L+I +    PP++  P +     I  +G
Sbjct: 3598 -VLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEISS----PPKITVPKRFQDVAIFEKG 3652

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVKDEGVYTLKAE 808
            ES ++     GNP+PTITW  + + VK     S+  + H+I  +K      +G Y + A+
Sbjct: 3653 ESAVMKIPFTGNPKPTITWMHDGEEVKGRNYHSEVTERHAILTIKDANKDQDGPYRITAK 3712

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLF 835
            N  G    SAVI ++    +  +PP +
Sbjct: 3713 NDLG--SDSAVIKIQ--INDRPDPPRY 3735



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 1/97 (1%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            ++ P F   LR  H   G + +FEC+V G P P I WF+ T  I  S  F++Y + D   
Sbjct: 3539 AVIPEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDK-Q 3597

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             L++ +VF ED   ++C A N  G  +S   L + +P
Sbjct: 3598 VLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEISSP 3634



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 80/347 (23%), Positives = 139/347 (40%), Gaps = 31/347 (8%)

Query: 759  VGNPRPTITWCKNNKPVKALPTKSD---GDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            V +PR  + W KN +P++    K +    +   I  +K  +  DE  YT       G A+
Sbjct: 1213 VSDPRARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTC----GDAK 1268

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
            T+    V +P  +      F+    ++   E+        V  +P   + W RN++ ++ 
Sbjct: 1269 TTCQFKVTDPEWD------FMKLLDDVEGIERDRATFECDV-NDPEAEVKWSRNDKELTS 1321

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
                    DG    LV+ N  S+ D G Y C   +   +++    V  DV+   F K L+
Sbjct: 1322 GGKYEIQVDGFKRRLVVKNCHSK-DDGPYTCKVLDK--ETTANLFVEPDVK---FFKKLE 1375

Query: 936  KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXX 992
               E E+G T++LEC+ S  H    KW  + + I+  D R E+ ++G             
Sbjct: 1376 NKREREKG-TLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLTRE 1434

Query: 993  DVGVIKCIVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVE---INSETADV 1047
            D G   C V ++ +   ++V E    P+   K    E+  K   ++E+    I       
Sbjct: 1435 DAGQYACQVGERSSKWEVIVDELPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMPSG 1494

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
             W++DG  +       D      +  + I +    D G+Y   L +E
Sbjct: 1495 HWKKDGNPLSEADT--DIRMTDTLASIRIPDAQRGDTGQYELTLTNE 1539



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 12/258 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G P P++ W+K   ++ +  ++ I  +    V+ + ++      +Y+  ASN  G+ +
Sbjct: 3565 VSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCRASNHGGSRT 3624

Query: 1656 VEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
                L++   P K   P   ++++   +  +   K P          +  +  E     +
Sbjct: 3625 SRANLEI-SSPPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEEVKGRNY 3683

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
               ++V        I+  N++ +  +R+ A+N +G      S+  VIK  ++        
Sbjct: 3684 H--SEVTERHAILTIKDANKDQDGPYRITAKNDLG------SDSAVIKIQINDRPDPPRY 3735

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSIN 1832
                 I +ESV ++W P   +GGS I  Y +E  +     W            I  LS N
Sbjct: 3736 PTCENIRDESVLLSWKPPLNDGGSFITQYIIEKCEPPNTNWIRVAVSRMCFHNITSLSAN 3795

Query: 1833 TTYQFRIYARNEIGTSLP 1850
              YQFR+ A N  G S P
Sbjct: 3796 KEYQFRVVAENFYGKSDP 3813



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 58/248 (23%), Positives = 102/248 (41%), Gaps = 19/248 (7%)

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
            +V+ VE  PKI    R   I+ GS+  LL   Q+ P P   W  ++K + K  H   S  
Sbjct: 4322 EVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYS 4381

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
               A++ ++  +  D G Y  R  N  G  +    V + D+     K +I +    S   
Sbjct: 4382 GGVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDKSDIFKSHKQS--- 4438

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
                   T  +T       +   D++   S  N T T +S       SS   R    +  
Sbjct: 4439 ------RTARTT----KSGFSFADSS---SSYNETSTSSSSTRTSNRSS---RHVEKSSY 4482

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            + S +S  +      +E  +++P     L  ++    + ++LTC   G P+P+V W+ +G
Sbjct: 4483 EDSYSSSRSSPRDKKREPSVEAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNG 4542

Query: 1520 KKLKTAKA 1527
            + +++  A
Sbjct: 4543 QLMQSDDA 4550



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 52/227 (22%), Positives = 99/227 (43%), Gaps = 11/227 (4%)

Query: 794  PKKVKDEGV-YTLKAENSEGIAE---TSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            PK ++D+   + + AEN  G+++    S  + +++P  + A  P F +  ++   ++  +
Sbjct: 3501 PKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDP--KAAVIPEFSSGLRKCHAQQGKS 3558

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
             K    V+  P P I W++    I  S       +G+   L++ +V  E D  +Y C AS
Sbjct: 3559 AKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGE-DQDEYSCRAS 3617

Query: 910  NSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKE 966
            N  G  +  A + I    K+T  K  Q     E+G++ +++   T +   T  W H+ +E
Sbjct: 3618 NHGGSRTSRANLEISSPPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEE 3677

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
            + G ++   + E              D G  +   K+   S   V+K
Sbjct: 3678 VKGRNYHSEVTERHAILTIKDANKDQD-GPYRITAKNDLGSDSAVIK 3723



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 13/189 (6%)

Query: 1006 TSTMLVVKE----TIPEFIRKLQDFEVKEKD-VAILEVEINSETA-DVVWERDGEIIKPK 1059
            T+ ++ +KE    T PEFI+KL   E+       I  V+++ +   DV W ++G +    
Sbjct: 3136 TTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNG-VPMGS 3194

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQN 1115
             ++    +   +  L       +DEGE  C + +    +SCT    + + PP+      +
Sbjct: 3195 TSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPLGRDSCTCNFKI-QSPPKFGKDFHD 3253

Query: 1116 QKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
            Q+V  G +   +I  +  G   V+  K+G E+  +  I++        L I D +LDDAG
Sbjct: 3254 QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQNGRIKIMPFDDYVSLTINDANLDDAG 3313

Query: 1175 EYSCEVGNS 1183
            +Y  EV N+
Sbjct: 3314 QYKVEVSNA 3322



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 509  APIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            AP F++KL P    P G  + F  QV G P P +TW++    +  +   ++  +DD V T
Sbjct: 3150 APEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDD-VFT 3208

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            L   E++  D G   C   N  G  S T    +++P
Sbjct: 3209 LRFTELYANDEGEIKCDISNPLGRDSCTCNFKIQSP 3244



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 43/135 (31%), Positives = 68/135 (50%), Gaps = 11/135 (8%)

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQV-IEPL---KSMIVRQGESVI 753
            V K +E  Y VVA+N  G +   +  K+     EKE P+V ++ L     + V+ GE + 
Sbjct: 2023 VGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLD 2082

Query: 754  LSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            +   V G P PT++W KN +PV  +A  T S+ D   + + K ++  D G YT+   N  
Sbjct: 2083 IPVGVSGTPTPTVSWEKNGRPVDNRAKCTSSEEDA-KLHVDKAER-GDTGKYTITVTNES 2140

Query: 812  GIAETSA-VITVEEP 825
            G       VI +++P
Sbjct: 2141 GSMSADVNVIVLDKP 2155



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 86/425 (20%), Positives = 153/425 (36%), Gaps = 48/425 (11%)

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-----LTIKKVENTDAGIYKLRLENNC 1366
            +A P+P+ +W   +  + +    K  ++    +     + IK V   DAG YK+  +N  
Sbjct: 33   EAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGGNNYNVMMDIKGVTQADAGTYKVVAKNKL 92

Query: 1367 GH--ADVEMNVTILDKPSPPG-------KPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            G   A + +N +   +    G       KP+  + D+    IC +          I +  
Sbjct: 93   GEVSASINLNFSAPGQKQQDGIAPNFTQKPSTRQADNGKETICLECQLTADPVPQISWFR 152

Query: 1418 EYQEIDTTEWISVKNITKTQTS------IQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
            + Q+I     I ++   K   +      I  +    +  +R  A N +  S+A+    + 
Sbjct: 153  DDQQIKDGGRIKIQTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNALGESNATIRLNFD 212

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKTA 1525
               K  K Q        K    +    I   C     P+P +TW +      DG + K  
Sbjct: 213  SDDK-GKPQGTRPSFTTKPAIKQVGGKIIFDCKVTADPKPTITWMKGTQALTDGGRYKMI 271

Query: 1526 KATYENRXXXXXXXX--XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ- 1582
            +   +N                  YKC+A N  G+   +  +  + K           Q 
Sbjct: 272  QTGDKNNYDVSMVIDKPGKDDGGEYKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQF 331

Query: 1583 --KHKVGDE---WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-------TTKEKTSVI 1630
              K  V  E    ++T  +E  P P + W++   +L+    Y+I            T+ +
Sbjct: 332  LAKPVVKQEKTNLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATL 391

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-----DKPSK-PEGPVIMREISRESVT 1684
             IK+ K +    +   ASN  G S+  +TL        DKPS+  E P   +   +++  
Sbjct: 392  NIKDPKPTDGGSFKCTASNDFGESNANITLNFQGAEQKDKPSEDQEKPAAPKPAEKKNKP 451

Query: 1685 IEWKP 1689
               KP
Sbjct: 452  APAKP 456



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 77/389 (19%), Positives = 148/389 (38%), Gaps = 47/389 (12%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSIT 790
            P+ I   ++++  +G+S     +++G   P +TW  +N    + VK +  K  G+ + + 
Sbjct: 4202 PRFIRKPRNILAAEGQSTKFDCKIIGASPPIVTWSYDNSVLSQSVKYMQ-KYRGNEYELK 4260

Query: 791  ILKPKKVKDEGVY---------------TLKAE-NSE-----GIAETSAVITVEEPTEEN 829
            I +  K+ D+G+Y               TLK E N E        +T+ +     P+   
Sbjct: 4261 ISR-LKMADKGLYTVIAENSFGKREEHATLKVEVNPELQRMPSSRDTTPMRRSRRPSMSP 4319

Query: 830  A-------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            A       E P      +   ++     KL+  V   PVP +TWY++N+ ++       +
Sbjct: 4320 APEVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCS 4379

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK-HLQKSYETE 941
            + G  +  +       +D+G Y C A N  G+    +RV ++     F K  + KS+  +
Sbjct: 4380 YSG-GVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDKSDIFKSH--K 4436

Query: 942  EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            + +T            +   +N+   S    R      R                 +   
Sbjct: 4437 QSRTARTTKSGFSFADSSSSYNETSTSSSSTR---TSNRSSRHVEKSSYEDSYSSSRSSP 4493

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK 1060
            +D++    +      PEF  +L    + E D   L   +  +   +V W  +G++++   
Sbjct: 4494 RDKKREPSV----EAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDD 4549

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
                    GH   L I +  + D+G Y C
Sbjct: 4550 AIKISAIAGH-HTLTIDSCIIDDDGNYVC 4577



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 1/77 (1%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            PE  + L+     +G  A FE E++ K    +RWFK   EI  S   ++  +G KQ L +
Sbjct: 3542 PEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIV 3601

Query: 1166 YDCDLDDAGEYSCEVGN 1182
            +D   +D  EYSC   N
Sbjct: 3602 HDVFGEDQDEYSCRASN 3618



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 3/128 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            GD   + A + G  P EV+  K+G+KL++ K+  IT K+    + I E+      KY I+
Sbjct: 686  GDACDLIAKVAGNEPIEVVCSKDGDKLKHSKDCQITFKDNVCRLYIPEVYPDDGGKYQID 745

Query: 1647 ASNTAGTSSVEVTLKVYDKP--SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
              N  G +    TL V + P  + PE   ++ +     V IE K P  +    + K   +
Sbjct: 746  LENEFGKAMTSATLVVSENPDMALPEVTPMLGDDPTGKV-IEQKIPEPEQVKPVEKIQPQ 804

Query: 1705 KHEPDNNR 1712
              EP+ ++
Sbjct: 805  IKEPEKSK 812



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
            ES  +E  V  L P  ++  Q+Q +++G        L + D+ V+W KDG+E+Q +    
Sbjct: 4635 ESRISEPDVDPLAPVFLSHPQSQSLDEGTAFKASCTLDEADS-VKWSKDGTEVQDTGRFN 4693

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             T D  K   +I      D+GEY+    NS+ ++
Sbjct: 4694 FTQDENKFTFEIPAALATDSGEYTVTAKNSRASS 4727



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 6/143 (4%)

Query: 459  QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518
            ++H T +    P    M  +  T  +++     +   P   KP  E    AP     LRP
Sbjct: 4284 EEHATLKVEVNPELQRMPSSRDTTPMRRSRRPSMSPAPEV-KPVEE----APKISFGLRP 4338

Query: 519  KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            +    GS  +    V+  P P++TW++    +     +   Y    VAT+ ++     D 
Sbjct: 4339 RLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSG-GVATIKVQSAKLVDT 4397

Query: 579  GTFTCVAKNAAGFASSTTELIVE 601
            GT+TC A N  G   +++ ++VE
Sbjct: 4398 GTYTCRAINELGEHETSSRVVVE 4420



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 60/224 (26%), Positives = 93/224 (41%), Gaps = 21/224 (9%)

Query: 705  EGTYTVVAVNR--EGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQ-GESVILSAQV 758
            E  + V AVN+  EGE S    L IK  EK     P+ I+ L    +   G  +I S QV
Sbjct: 3117 EFEFRVRAVNQAGEGEPSGTTGL-IKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQV 3175

Query: 759  VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816
             G P P +TW KN  P+ +           +  L+  ++   DEG   +K + S  +   
Sbjct: 3176 HGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEG--EIKCDISNPLGRD 3233

Query: 817  SAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
            S     +  +     PP F   F  Q++ + E+  IK+    T  P          E++ 
Sbjct: 3234 SCTCNFKIQS-----PPKFGKDFHDQQVELGEQFKIKIPFSGT-GPFEVKVRKNGREVVQ 3287

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
                    FD + + L I + + + D+G YK   SN+ G +  G
Sbjct: 3288 NGRIKIMPFD-DYVSLTINDANLD-DAGQYKVEVSNAGGAAELG 3329



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 6/107 (5%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSI 789
            E P+    L  + + +G+ + L+  V G P P + W  N + ++   A+   +    H++
Sbjct: 4503 EAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTL 4562

Query: 790  TILKPKKVKDEGVYTLKAENSEGIA--ETSAVITVEEPTEENAEPPL 834
            TI     + D+G Y  KA+N  G A   TS  +T   P + +  P +
Sbjct: 4563 TI-DSCIIDDDGNYVCKAKNPGGQASSRTSVQVTENRPVKSSTPPQI 4608



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            GD   +T  ++G P PEV W+ NG  +++D    I+       + I          Y  +
Sbjct: 4519 GDRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIIDDDGNYVCK 4578

Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKP--PLDDGGLELTKYAI 1703
            A N  G +S   +++V + +P K   P  ++  S     IE      L+DG     +  I
Sbjct: 4579 AKNPGGQASSRTSVQVTENRPVKSSTPPQIKSSSPRPDFIEHPTGVSLEDGDKATLESRI 4638

Query: 1704 EKHEPD 1709
               EPD
Sbjct: 4639 S--EPD 4642



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 50/242 (20%), Positives = 88/242 (36%), Gaps = 15/242 (6%)

Query: 947  ILEC-QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI----V 1001
            +L C Q++      WY + K+++   H      G             D G   C     +
Sbjct: 4349 LLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYTCRAINEL 4408

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
             + ETS+ +VV++   +F  K   F+  ++       +     AD     +         
Sbjct: 4409 GEHETSSRVVVEDRAHDF-DKSDIFKSHKQSRTARTTKSGFSFADSSSSYNETSTSSSST 4467

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
            +       H+ K     +S  D   YS              VE P E  T+L    +N+G
Sbjct: 4468 RTSNRSSRHVEK-----SSYEDS--YSSSRSSPRDKKREPSVEAP-EFTTQLSPLSLNEG 4519

Query: 1122 NKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
            ++      +  + +  V WF +G  +Q  + I+++       L I  C +DD G Y C+ 
Sbjct: 4520 DRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIIDDDGNYVCKA 4579

Query: 1181 GN 1182
             N
Sbjct: 4580 KN 4581



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 68/305 (22%), Positives = 118/305 (38%), Gaps = 21/305 (6%)

Query: 1099 EVTVVELPPEIITRLQNQKVNKGN--KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156
            EV  VE  P+I   L+ + +  G+  K    ++ T     V W+KD  ++    H   + 
Sbjct: 4322 EVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPK-VTWYKDNKDVAKDPHYMCSY 4380

Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
             G    +K+    L D G Y+C    E+G  + ++ + VE+ + +F  +   F     + 
Sbjct: 4381 SGGVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFD-KSDIFKSHKQSR 4439

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             A  T          + Y + S    +   T  S+   R  + +   ED          D
Sbjct: 4440 TARTTKSGFSFADSSSSYNETST---SSSSTRTSNRSSRH-VEKSSYEDSYSSSRSSPRD 4495

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
             K   +  VE  EF  ++        +  G  + L    +  P+P  EW  N ++++   
Sbjct: 4496 KK--REPSVEAPEFTTQL----SPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDD 4549

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILE 1391
              K S  +   +LTI      D G Y  + +N  G A    +V + + +P     P   +
Sbjct: 4550 AIKISAIAGHHTLTIDSCIIDDDGNYVCKAKNPGGQASSRTSVQVTENRPVKSSTPP--Q 4607

Query: 1392 IDSSS 1396
            I SSS
Sbjct: 4608 IKSSS 4612



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 11/180 (6%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F KK + +   E   ++LEC+        + WL  GE I  D+   + +     +Y  V+
Sbjct: 1370 FFKKLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDP-RLEVTRKGELYKIVI 1428

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVI 753
            K  N+ +   G Y      R  +  + IV ++     +PPQ+   +  + +IV++GE + 
Sbjct: 1429 K--NLTREDAGQYACQVGERSSKWEV-IVDELP----KPPQINAKDIPEEIIVKKGEVIE 1481

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +    +G P P+  W K+  P+    T     DT +   +   +  D G Y L   N  G
Sbjct: 1482 IGIPFIGVPMPSGHWKKDGNPLSEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVG 1541



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 19/81 (23%), Positives = 35/81 (43%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G E+ +   ++  P P+V WYK+   +  D  Y  +     + I+++  K   +  YT
Sbjct: 4342 QAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYT 4401

Query: 1645 IEASNTAGTSSVEVTLKVYDK 1665
              A N  G       + V D+
Sbjct: 4402 CRAINELGEHETSSRVVVEDR 4422



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 1501 LTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDH 1556
            LTC+    P PKVTWY+D K   K      +Y                   Y C A N+ 
Sbjct: 4350 LTCV-QSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYTCRAINEL 4408

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK 1585
            GE ETS  V ++ +        DI + HK
Sbjct: 4409 GEHETSSRVVVEDR-AHDFDKSDIFKSHK 4436



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 6/124 (4%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRN 859
            Y + A N  G +E S    V +   E   P + ++      EI VK    + +   V+  
Sbjct: 2031 YRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGT 2090

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P+++W +N   +      T +   E+ +L +   +   D+G Y    +N +G  S   
Sbjct: 2091 PTPTVSWEKNGRPVDNRAKCTSS--EEDAKLHVDKAERG-DTGKYTITVTNESGSMSADV 2147

Query: 920  RVTI 923
             V +
Sbjct: 2148 NVIV 2151



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 22/77 (28%), Positives = 31/77 (40%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G  PP V W  + + L    +Y    +     ++I  LK +    YT+ A N+ G   
Sbjct: 4225 IIGASPPIVTWSYDNSVLSQSVKYMQKYRGNEYELKISRLKMADKGLYTVIAENSFGKRE 4284

Query: 1656 VEVTLKVYDKPSKPEGP 1672
               TLKV   P     P
Sbjct: 4285 EHATLKVEVNPELQRMP 4301



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 20/145 (13%)

Query: 697  ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQG 749
            ++ + + +E  + V AVN+ G     EA+ P++ K +   +  P+++  + LK + V+ G
Sbjct: 1718 VSGLTENREYIFRVSAVNKAGKSEPSEATPPVLTKSR---RVRPRIMNKDDLKPIRVKVG 1774

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS------DGDTH---SITILKPKKVKDE 800
            +   +  + +G P P I W K     K  P +       D  T    ++T  +P + KD 
Sbjct: 1775 KDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSR-KDT 1833

Query: 801  GVYTLKAENSEGIAETSAVITVEEP 825
             +Y +   N  G       + V  P
Sbjct: 1834 AMYNVTVTNKHGSDTADVEVVVLGP 1858


>UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin a -
             Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 32757

 Score =  312 bits (765), Expect = 9e-83
 Identities = 324/1447 (22%), Positives = 577/1447 (39%), Gaps = 89/1447 (6%)

Query: 628   ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
             +LEG  P F+ K +     E  +++L C  V+     + W   G EI P +N+ +  +  
Sbjct: 11713 VLEG-EPYFTTKLQDYTAVEKDEVVLMCE-VSKSSAQVKWFKDGNEITPSKNVLIKADGK 11770

Query: 688   MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                   +L +   +K   G Y     + +  A L I       E+   +++ PL S+ V 
Sbjct: 11771 KR----ILTVKKAEKGNIGEYVCDCGSDKTAAKLNI-------EERDIKIVRPLYSVEVT 11819

Query: 748   QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--SITILKPKKVKDEG---- 801
             + E+     ++         W      +   P  S    H  SIT++K  ++K+EG    
Sbjct: 11820 ETETARFETEI-SEEDVHGHWKLKGDALHQSPVISFTPKHYFSITMMKDCEIKEEGTKHM 11878

Query: 802   --VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
               +Y ++ + +  +  ++A    +      A     +   +++TV    T      ++  
Sbjct: 11879 LILYNVRMDMAGAVDFSAANAKSKAQLRVKARVIGLLRPLKDVTVTAGETATFDCELSYE 11938

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
              +P + W+     + PS+ +    +G +  L + +V    ++G+ K  A +   +    A
Sbjct: 11939 GIP-VEWFLGGTKLEPSDRVVTRAEGRSHTLTLRDVKLT-EAGEVKLTAKDFLTQ----A 11992

Query: 920   RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978
             ++ ++   V F K L+     EE  T  LEC+ S      +W+ + +EI      +++ +
Sbjct: 11993 QLIVNEPPVEFTKPLEDQ-TVEEEATAELECEVSKEKAEVRWFRDGQEIRKTKKYDMVAD 12051

Query: 979   GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
             G             D     C  K  +TS  L V+    EF + L D EVKEK+ A  E 
Sbjct: 12052 GCKRKLVIHDCTLDDSKTYTCDAKHFKTSAFLNVEPPYVEFTKPLHDVEVKEKESARFEC 12111

Query: 1039  EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
             E++ E+A V W RDG  I+ K  KY+    G  R L I  +   DE EY C  R    + 
Sbjct: 12112 EVSRESAKVRWFRDGNEIR-KGKKYEMISEGVKRILIISKSVFDDEAEYECDARTSKSSG 12170

Query: 1099  EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158
              +TVVE        L N +  + +      E++K  A V W+K   E+      +   DG
Sbjct: 12171 MLTVVEEEARFTKNLANIEGTETDSVKLICEVSKPSAEVTWYKGDQELPEVGRYEHITDG 12230

Query: 1159  KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
             KK+ L I    +DDAGEY C++  S+ T  L + E +  F  R P+   V     A    
Sbjct: 12231 KKRILIIKGLRMDDAGEYHCKLPTSQTTGNLRINELAAEFIAR-PQNQEVVEGEKAQFVC 12289

Query: 1219  EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
              +  +T +V W K  + ++  +K+ +IS+ KKR LI++ C   D+  +  V+L   +   
Sbjct: 12290 SVSKDTYEVKWLKGNTELQSDDKYEIISEGKKRVLIVKNCELKDEGGF--VVLIGTTRAS 12347

Query: 1279  LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
               + V+E   +I+   ++ +   G +  L  +         +W+ N++ + +        
Sbjct: 12348 ADLTVLE-KLRIITPLKDTKANEGQETVLNCEVNT-EGAKAKWLKNNETLFESSKFIMVQ 12405

Query: 1339  DSKSASLTIKKVENTDAGIYKLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
                  SL IK  + +D   Y + L N     A    N+T+ +             +   I
Sbjct: 12406 KDNVFSLRIKDTQKSDEANYTITLTNQRAEQAKSSANITVHE-------------EDLRI 12452

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAV 1456
              +  ++ +      I +     ++  T +W+   + IT ++  +  +            +
Sbjct: 12453 VVPPEDVDTQEKKAISFTCKVNRQNVTVQWMKAGQEITLSKRILYRVDKEK----HTLTI 12508

Query: 1457  NEVDISDASETTEYYKVIKETK----IQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQP 1511
              +  ++D  E T      K T      ++PT     L + T    ED E +C      + 
Sbjct: 12509 KDCSLADEGEYTVIAGPDKATAELIISEAPTDFTAQLSDQTITEFEDAEFSCEL-TKEKA 12567

Query: 1512  KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
              + WYRDG++++        R                +C       +  T   + +++ P
Sbjct: 12568 DIKWYRDGREIREGPRYQFERDGKTCRLRIKECRPDDECEYACGVDDKRTRARLFVEETP 12627

Query: 1572  VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             V  I           G + +V  V       EV W +N   +    +Y + ++ K   ++
Sbjct: 12628 V-EIVRPPTDVFEPPGSD-VVYEVELNKDRVEVKWLRNNMTIVQGDKYQMMSEGKIHRLQ 12685

Query: 1632  IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
             + E++     +Y + A +    + +E+             P I + + ++ VT   KP +
Sbjct: 12686 VCEIRPRDQGEYRVIAKDKDARAKLELAAV----------PTI-KTLDQDLVTDAGKPFV 12734

Query: 1692  DDGGLELTKYAIEKHEPDNNRWIKVAD---VDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                G+    Y + + E   N      D      D   Y ++   ++ E  +++I QN  G
Sbjct: 12735 --MGVPYNAYPLAEAEWFYNDISLPKDNIHTSIDRTEYRLKDPKKSEEGRYKIIVQNKHG 12792

Query: 1749  FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
               EA     I +K  +DVP            D E + I W   E +GGS I+ Y VE + 
Sbjct: 12793 KGEAF----INLK-VIDVPGPVKNLQVVDTADGE-ISIAWEEPESDGGSKILAYVVERRD 12846

Query: 1809  -EGKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
              + K W             +  L  ++ Y FR+ ARN +G+     +D  +        P
Sbjct: 12847 VKRKTWTLATDCADSTEYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVP 12906

Query: 1867  SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
               P+N +V        T+ W  P  +GGS IT+YIIE +      W  ++          
Sbjct: 12907 DAPQNVIVGNVNKFGATVSWEPPLFDGGSEITSYIIELRDRTSVVWAPVMVTKPHERSAI 12966

Query: 1927  IENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
             I ++ E  E IFR+ AEN  G+  P+ + + V++      PSPP           + ++T
Sbjct: 12967 INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMDPIERPSPPLNLTHSEQTKDSCLLT 13026

Query: 1986  SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
              W TP  +GG  + GY I   +     W+         L + +  L     Y  R+ A N
Sbjct: 13027 -WETPLKNGGTAITGYIIERCEEGTDKWLRCNARLCPDLLYRMSGLKFGKKYSYRVIAEN 13085

Query: 2046  EIGLSEP 2052
               G S+P
Sbjct: 13086 AAGQSDP 13092



 Score =  281 bits (689), Expect = 1e-73
 Identities = 327/1448 (22%), Positives = 576/1448 (39%), Gaps = 105/1448 (7%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V  G     +C L     P + W   G ++ P + +    E   H     L + +VK  +
Sbjct: 11923 VTAGETATFDCELSYEGIP-VEWFLGGTKLEPSDRVVTRAEGRSH----TLTLRDVKLTE 11977

Query: 705   EGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPR 763
              G   + A +   +A L +         EPP +  +PL+   V +  +  L  +V    +
Sbjct: 11978 AGEVKLTAKDFLTQAQLIV--------NEPPVEFTKPLEDQTVEEEATAELECEV-SKEK 12028

Query: 764   PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
               + W ++ + +   K     +DG    + ++    + D   YT  A++ +    TSA +
Sbjct: 12029 AEVRWFRDGQEIRKTKKYDMVADGCKRKL-VIHDCTLDDSKTYTCDAKHFK----TSAFL 12083

Query: 821   TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
              VE P  E  +P        ++ VKEK + +    V+R     + W+R+   I   +   
Sbjct: 12084 NVEPPYVEFTKP------LHDVEVKEKESARFECEVSRESA-KVRWFRDGNEIRKGKKYE 12136

Query: 881   QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
                +G    L+I+    + D  +Y+C A  S  KSS    +T+  E+  F K+L  + E 
Sbjct: 12137 MISEGVKRILIISKSVFD-DEAEYECDARTS--KSS--GMLTVVEEEARFTKNLA-NIEG 12190

Query: 941   EEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
              E  +V L C+ S  +    WY   +E+  +   E I +G+            D G   C
Sbjct: 12191 TETDSVKLICEVSKPSAEVTWYKGDQELPEVGRYEHITDGKKRILIIKGLRMDDAGEYHC 12250

Query: 1000  IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
              +   +T+  L + E   EFI + Q+ EV E + A     ++ +T +V W + G      
Sbjct: 12251 KLPTSQTTGNLRINELAAEFIARPQNQEVVEGEKAQFVCSVSKDTYEVKWLK-GNTELQS 12309

Query: 1060  KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
              +KY+    G  R L ++N  + DEG +  ++     +A++TV+E    IIT L++ K N
Sbjct: 12310 DDKYEIISEGKKRVLIVKNCELKDEGGFVVLIGTTRASADLTVLE-KLRIITPLKDTKAN 12368

Query: 1120  KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
             +G +     E+    A  +W K+   +  S+   +        L+I D    D   Y+  
Sbjct: 12369 EGQETVLNCEVNTEGAKAKWLKNNETLFESSKFIMVQKDNVFSLRIKDTQKSDEANYTIT 12428

Query: 1180  VGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234
             + N     +K +A +TV E  +   +  PE +          T ++  + + V W K   
Sbjct: 12429 LTNQRAEQAKSSANITVHEEDLRIVVP-PEDVDTQEKKAISFTCKVNRQNVTVQWMKAGQ 12487

Query: 1235  VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE 1294
              I  +++     D +K TL I+ C+  D+ EYT +    K+T +L +   E P       
Sbjct: 12488 EITLSKRILYRVDKEKHTLTIKDCSLADEGEYTVIAGPDKATAELIIS--EAPTDFTAQL 12545

Query: 1295  REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
              +  I    D     +     + + +W  + + I++    +   D K+  L IK+    D
Sbjct: 12546 SDQTITEFEDAEFSCELTK-EKADIKWYRDGREIREGPRYQFERDGKTCRLRIKECRPDD 12604

Query: 1355  AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
                     E  CG  D      +  + +P      +EI     ++   EP     S ++Y
Sbjct: 12605 ------ECEYACGVDDKRTRARLFVEETP------VEIVRPPTDVF--EPPG---SDVVY 12647

Query: 1415  YVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
              V   ++    +W+   N+T  Q    Q +     +R +   +   D  +     +    
Sbjct: 12648 EVELNKDRVEVKWLR-NNMTIVQGDKYQMMSEGKIHRLQVCEIRPRDQGEYRVIAKDKDA 12706

Query: 1474  IKETKIQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYEN 1531
               + ++ + PT++   +++ T+  +   +   +   P  +  W Y D    K    T  +
Sbjct: 12707 RAKLELAAVPTIKTLDQDLVTDAGKPFVMGVPYNAYPLAEAEWFYNDISLPKDNIHTSID 12766

Query: 1532  RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-------VITISNEDI---- 1580
             R               YK I  N HG+ E    + +   P       V+  ++ +I    
Sbjct: 12767 RTEYRLKDPKKSEEGRYKIIVQNKHGKGEAFINLKVIDVPGPVKNLQVVDTADGEISIAW 12826

Query: 1581  KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
             ++    G   ++  V+E        W        +  EY +T  ++ S    K L R  +
Sbjct: 12827 EEPESDGGSKILAYVVERRDVKRKTWTL-ATDCADSTEYTVTGLQRDS----KYLFRVCA 12881

Query: 1641  SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
                     N     +V+   K +D P  P+  VI+  +++   T+ W+PPL DGG E+T 
Sbjct: 12882 RNRVGSGPNVETDKAVQAKNK-FDVPDAPQN-VIVGNVNKFGATVSWEPPLFDGGSEITS 12939

Query: 1701  YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759
             Y IE  +  +  W  V        +  I  + EN EY+FRV A+N  G  + +  + P+ 
Sbjct: 12940 YIIELRDRTSVVWAPVMVTKPHERSAIINDVIENKEYIFRVKAENKAGIGKPSAATNPVK 12999

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXX 1818
             I   ++ PS             +S  +TW    KNGG+ I  Y +E  +EG  KW     
Sbjct: 13000 IMDPIERPSPPLNLTHSEQ-TKDSCLLTWETPLKNGGTAITGYIIERCEEGTDKWLRCNA 13058

Query: 1819  XX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     R+  L     Y +R+ A N  G      SD    +G  L     P      +
Sbjct: 13059 RLCPDLLYRMSGLKFGKKYSYRVIAENAAG-----QSDPSNIVGPVLA--DDPHYAPTLD 13111

Query: 1877  STSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
              ++    L+   P   +   PIT Y I   T K       +T G  V         E   
Sbjct: 13112 LSAFKDGLEVFVPNPLSIRVPITGYPI--PTAKWTFGENALTAGDRVSMVTKSTFTELVI 13169

Query: 1936  IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWD 1993
                  + + T  ++L  +  SV  E    V + P+AP  L++  V    V   W  PE D
Sbjct: 13170 TPSVRADKGTYSLTLENDVASVSGEIEVNVIASPSAPKDLKVAEVTRKHVHLMWEAPEHD 13229

Query: 1994  GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
             GG+P+ GY +  R+V++  W++V    +   ++ + D+ E   Y+ R+ A N+ G  EP 
Sbjct: 13230 GGSPITGYQVEKREVSRKTWVKV-MSGLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPA 13288

Query: 2054  ESDEPFKV 2061
               ++P  V
Sbjct: 13289 YIEDPVNV 13296



 Score =  266 bits (652), Expect = 5e-69
 Identities = 205/773 (26%), Positives = 327/773 (42%), Gaps = 42/773 (5%)

Query: 1292  DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
             D  +   ++  + + L V  +  P+P  +W      + +    +  +      L I  V 
Sbjct: 24747 DLRKCVTVRASATLRLFVTIRGRPEPEVKWKKADGTLPE--RAQIEVTGSYTGLVIDNVN 24804

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
               D G Y L LENN G     +NV +LD PS P    + ++   S+ + W+ P+  G + 
Sbjct: 24805 RFDTGKYVLTLENNIGSKSAFVNVKVLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAK 24864

Query: 1412  IIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             I +Y+VE +E     + S+  N  +    + +L+    Y FR  AVNE+ +   +ETTE 
Sbjct: 24865 ITHYIVEKRESKRLAFTSITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEA 24924

Query: 1471  YKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
              K+    +   KI    V +    ++ E  +    + I G +    V     G    TA 
Sbjct: 24925 VKISQAPLPPGKITVIDVTRHTVTLSWEKPDHDGGSKITGYM----VEMMTKGSDKWTAC 24980

Query: 1527  ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET----SCVVG--IQQKPVITISNEDI 1580
              T +                 ++  A ND G+ +     + VV   I  +P+I +     
Sbjct: 24981 VTIK-ALEATIEGLTTGEEYSFRITAINDKGKSDPKPLGAPVVARDITIEPIIDLMFNTY 25039

Query: 1581  KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
               K   GD+  +     G P PEV W K+G+ L+     N+ T +  S I IK+  R  +
Sbjct: 25040 SVK--AGDDLKIDVPFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDA 25097

Query: 1641  SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
              KY I  +NT G  S E+++ V DKP  P G + + EIS + +++ W PP+ DGG ++  
Sbjct: 25098 GKYEITLTNTFGVKSAEISVIVLDKPG-PPGAIKVEEISADFISLSWDPPIYDGGCQINN 25156

Query: 1701  YAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
             Y +EK +     W I  A V R   +  + +L +  EY FR+ A+N  G S A++S PIV
Sbjct: 25157 YVVEKRDTTTTAWQIVSATVAR--TSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIV 25214

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX 1818
              +     P                + +TW     +GGSPI+ Y +E K Q    W     
Sbjct: 25215 AQYPF-TPPGPPTSLQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNR 25273

Query: 1819  XXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     ++  L     YQ+R+YA N  G      + D ++      PPSQPR   V  
Sbjct: 25274 GLITETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPSQPR---VMN 25330

Query: 1877  STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936
              T  SV+L WT+PE +GG+ +T YI+E   +    W K            +  + E    
Sbjct: 25331 ITRTSVSLSWTKPEFDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRY 25390

Query: 1937  IFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              FRI A+N  G+ S P+ES      K      PP   +E ++    ++          G 
Sbjct: 25391 DFRIIAKNAAGLFSEPSESTGPVTVKDDV--DPPRITIEDKLRQLVVIKA--------GE 25440

Query: 1996  APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
                +   I+ R +    W + GK      +F I     + T ++R   R + G
Sbjct: 25441 ILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLTSTTLIVRDAIRRDSG 25493



 Score =  266 bits (651), Expect = 6e-69
 Identities = 288/1212 (23%), Positives = 488/1212 (40%), Gaps = 99/1212 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV+K+       GS V+ +  ++G     + WF+ T I++         DD N+ T  
Sbjct: 5083 PSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRD--------DDPNITT-- 5132

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
                      TF     N A  A S   +       +HG + T             A + 
Sbjct: 5133 ----------TFE---NNIAVLAISNVAI-------NHGGKYTCQAENEAGKQKCEATVT 5172

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
               P  F +KP    V  G    LEC++   P+  + W   G+E+       +  + ++ 
Sbjct: 5173 VQEPARFVEKPPCISVTAGDSATLECKVSGSPDLKVKWFKDGKEMAGGRKYKITFKENV- 5231

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               +VLKI + ++     Y V   NR G+      + +     EPP      +S  V  G
Sbjct: 5232 ---AVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINV----LEPPVFSLKPQSQDVIPG 5284

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLK 806
             +V+L+A   G     I W + +K +    T   K + ++ S+  L   K      YT +
Sbjct: 5285 TTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLE-LHALKPSQSAKYTCQ 5343

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI-KLVARVTRNPVPSIT 865
              N  G    +A + V+       EPP F+ +     +   G++  L  +V  +P  SI 
Sbjct: 5344 VSNDAGKVSCTAALFVK-------EPPKFVMKLDLTKLVLNGSLATLECKVAGSPEISIR 5396

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            WY+N   I   +     F      L I++   E DSGDY C AS+ AG       VT+  
Sbjct: 5397 WYKNETEIGSDDKYQMAFTDSVATLRISSCCVE-DSGDYICQASSDAGSDRCSCLVTVK- 5454

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXX 983
            E   FVK  + S E  +G  V+LE   S +       + + K+I   D R II   +   
Sbjct: 5455 EPPEFVKPFE-SKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRN-DRRHIISLTKDVA 5512

Query: 984  XXXXXXXX-XDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEV-KEKDVAILEV 1038
                      D G  +C V +   Q +   LV  +  P F++K+ +  V   KDV++  V
Sbjct: 5513 ALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPSFVQKMDNTNVLLAKDVSLQCV 5572

Query: 1039 EINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095
               S    + W +D   IK  ++ +  FE +  +  +YI +  +   G+Y+C  ++E+  
Sbjct: 5573 LKGSMPMTISWMKDDHEIKESEHVQISFENQTAV--IYISSVQLKHGGKYTCHAQNEAGS 5630

Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152
              CTA +TV E P  I  + ++  V   + AT E   +    L  +W KDG+E+      
Sbjct: 5631 QKCTAVLTVKE-PANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNELTSGRKY 5689

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFI 1206
            ++        LKI   +  DAGEY+ EV    G S C A++TV +  I  +FT +L E  
Sbjct: 5690 KIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETE 5749

Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             +  +      +      ++VTW+K+   IE  EK   I      +L I +    D   Y
Sbjct: 5750 SIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNY 5809

Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            TC+  +   + +    + V+ PP I++      +  GS V   V     P     W  ++
Sbjct: 5810 TCIAKNQAGSDQCSGTLKVKEPPSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDT 5869

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
            K +          +  S+S+ +   + +D+G Y   + N+ G    +  + + + P    
Sbjct: 5870 KEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDSCQATLFVKEPPKFTR 5929

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEI---DTTEWISVKNITKTQTSIQ 1441
            KP  + +   S  + + E + TG   I  Y+  +  +I   D  +   V ++ + +    
Sbjct: 5930 KPEKITVVKPSQLVVF-ECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLARLEIISS 5988

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
            ++K +  Y   A   NE      SE+      +KE     P + KPL  +      +   
Sbjct: 5989 DIKDSGVYYCEAR--NEA----GSESCSMDLRVKE----PPVLVKPLSPLEVVNGSNAYF 6038

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
             C+  G    +VTW +D K +K++         ++                Y+CI  N+ 
Sbjct: 6039 ECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQCIVANEV 6098

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G   +   + I++ P      E++     +G       V+ G PP  + W K+ + +  D
Sbjct: 6099 GSCSSQSTLSIKEPPSFVERIENVVT--VLGKMVEFKCVVRGSPPLSIQWQKDESWILED 6156

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
                 T +   + + I   +  HS KYT +A N AG      TL V + P   E P ++ 
Sbjct: 6157 PSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEKPEVIN 6216

Query: 1677 EISRESVTIEWK 1688
              + + V+ E K
Sbjct: 6217 VTAGDPVSFECK 6228



 Score =  260 bits (636), Expect = 4e-67
 Identities = 221/844 (26%), Positives = 361/844 (42%), Gaps = 54/844 (6%)

Query: 1226  DVTWYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLLDAKSTTKL--- 1279
             D+T Y  ++ + + +++T+++ +   T     I   TE+ + +     L+ +   +    
Sbjct: 21422 DITGYIVETCLPEEDEWTIVTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEPASV 21481

Query: 1280  ----KVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
                 K E    PP+I    D  +   I+  S + L V  +  P P   W  + +  +   
Sbjct: 21482 PGSPKAEDRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRW--SREKGEPLD 21539

Query: 1333  HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
                  I     +L I+ V+  D G Y L +EN+ G     +NV +LD P  P    I EI
Sbjct: 21540 RASIEITPSFTTLLIENVDRFDGGKYMLTVENSSGTKTAFINVRVLDTPGAPQNLTIKEI 21599

Query: 1393  DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYR 1450
                S+++ WD P   G S I +Y+VE +E  T +  S+ N +  KT   I +L+  + Y 
Sbjct: 21600 TKDSVSLIWDPPVIDGGSRIRHYIVEKRE-STRKAYSIVNASCPKTSWRIGDLQEGNLYF 21658

Query: 1451  FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVP 1509
             FR  A NE  +    ET E  K I E  +  P  +  LK +T+       E     GG  
Sbjct: 21659 FRILAENEYGVGLPVETMEAIK-ISERPL--PPGKVTLKEVTSNSVTLSWEKPDHDGG-- 21713

Query: 1510  QPKVTWY---RDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSC 1563
               ++T Y     GK   K  +                     ++  A N+ G  +     
Sbjct: 21714 -SRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQGEEYSFRISATNEKGISDPRPLS 21772

Query: 1564  VVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
             V  I +  VI  + + +     V  GD+  +       P   V+W K+G  L+     N 
Sbjct: 21773 VPVIAKDVVIAPAFKLLFSTFSVLAGDDLKIDVPYVAQPKAAVVWQKDGISLKETTRVNT 21832

Query: 1622  TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
                E+   + +KE  R    KYTI+ +N+AG ++ ++ + V DKP  P GP+ + E++ +
Sbjct: 21833 EVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVLDKPGPPTGPIKIEEVTAD 21892

Query: 1682  SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFR 1740
             SVT+ W+PP  +GG  +  Y +EK +     W I  A V R   T    +L   CEY FR
Sbjct: 21893 SVTLSWQPPEYEGGCSINNYIVEKRDTSTTNWQIVSATVAR--TTTKAARLKTGCEYQFR 21950

Query: 1741  VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
             + A+N  G S  + SE +V +   ++P              ES+ + W     +GGS I+
Sbjct: 21951 IAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSA-TKESMVVVWNKPSSDGGSKIL 22009

Query: 1801  DYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
              Y +E K++    W           R  I  L     Y+FR+YA N +G S      +  
Sbjct: 22010 GYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFRVYAENIVGLSKASKVSEIQ 22069

Query: 1858  TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
                    PP +P   +V  S   SVTL+WT P+ +GG  IT Y++E K +    W K   
Sbjct: 22070 VARDPCDPPGKPEAVIVKRS---SVTLRWTPPQFDGGIKITGYVVEKKELPNGRWMKASF 22126

Query: 1918  VGGSVHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976
                   E  +  + E+ +  FR+ A N  GV S+P++S      K      PP   L+ +
Sbjct: 22127 ANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKDEV--DPPQIDLDAK 22184

Query: 1977  MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
                 N+V+ +  +   D G  +LG     + +    W++ G+   NT +  I++     T
Sbjct: 22185 -YSQNVVVNAGESFRIDAG--ILG-----KPIPSVHWIKSGEELTNTARLEIKNTDFTTT 22236

Query: 2037  YMIR 2040
               ++
Sbjct: 22237 LSVK 22240



 Score =  249 bits (610), Expect = 6e-64
 Identities = 182/672 (27%), Positives = 294/672 (43%), Gaps = 31/672 (4%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             +  G  + + + ++  P P   W  +   +          D     LTI   +  DAG Y
Sbjct: 23671 VHAGGSMRINIPFKGRPIPEINWTKDDGDLPDKAQIDKGPDF--THLTINICDRNDAGKY 23728

Query: 1359  KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
              L L+N+ G     ++V +LD P  P    + +I  + + + W+ P   G S I  Y+++
Sbjct: 23729 TLTLQNSAGTKSAFVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIID 23788

Query: 1419  YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV---- 1473
              +E     + ++    +KT   + +L     Y FR  A NE  I    ET E  K     
Sbjct: 23789 KRESTRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPP 23848

Query: 1474  IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGKKLKTAKATYEN 1531
             +   K+    V K   +++ +  +    + I G     QPK      G + +   AT   
Sbjct: 23849 LSVGKVTLTDVTKTTASLSWDKPDHDGGSRILGYYIEMQPK------GSE-EWIVATVCK 23901

Query: 1532  RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQKPVITISNEDIKQKHKV--G 1587
                              + +A+N+ G+ +   +    I +   I  S +     + V  G
Sbjct: 23902 TCEGTVAGLSSGQEYLLRVLAYNEKGKSDPRPLASPVIAKDVTIEPSFKLTFNTYSVQSG 23961

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
             ++  V    +G P P++ W K+G  L+     N+++   ++V++IKE  R  S KYTI A
Sbjct: 23962 EDLKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITA 24021

Query: 1648  SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
             +N  GT + EV + + DKP  P GPV + E+S   V I W+PP+  GG ++  Y +EK +
Sbjct: 24022 TNNIGTVTEEVAIIILDKPGPPTGPVKIDEVSATYVVISWEPPVYTGGCQINNYVVEKRD 24081

Query: 1708  PDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
                  W  V A + R   T  I KL    EY FRV A+N  G S +++S P+V+      
Sbjct: 24082 TTTTNWQTVSATIAR--TTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTE 24139

Query: 1767  PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR 1825
             P+          +  + + I W P   NGGSPII Y +E K++    W           R
Sbjct: 24140 PA-APGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTR 24198

Query: 1826  IQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883
             ++   L     Y++R++A N  G S      + +       PP  P   V+   T   +T
Sbjct: 24199 LRTNGLEEGIEYEYRVFAENIAGISPSSKVSESVVARDPCDPPGTPEAIVI---TRNLIT 24255

Query: 1884  LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
             L+WT+P+ +GGS IT YIIE K +    W K         +  I  + E+    FR+ A 
Sbjct: 24256 LQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQFTITGLHEEQRYEFRVIAR 24315

Query: 1944  NTVGV-SLPTES 1954
             N  G+ S+P+ES
Sbjct: 24316 NAAGILSVPSES 24327



 Score =  249 bits (609), Expect = 7e-64
 Identities = 181/674 (26%), Positives = 297/674 (44%), Gaps = 34/674 (5%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAG 1356
             +K GS  TL V ++  P P+  W  N   +      + SID+     S+TI++    D+G
Sbjct: 25833 VKDGSSFTLRVPFKGKPVPHVMW--NKPDVDL--RVRASIDTTDTCTSVTIEQATRDDSG 25888

Query: 1357  IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
              Y + L+N  G A + ++V +LD P PP    + E+  SS  I WD P+N G + +  Y+
Sbjct: 25889 KYTVTLQNVAGTATLTLSVKVLDSPGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYL 25948

Query: 1417  VEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
             V+ +E     W  + N     T  + NL+    Y FR    NE  +    ET E  K+  
Sbjct: 25949 VDLREATKMGWSRISNSCPRLTYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEGTKI-- 26006

Query: 1476  ETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGK----KLKTA 1525
              T+  SP    P   +T    E + L  +     GG  +    V     G+    K  + 
Sbjct: 26007 -TEKPSPP---PKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCGST 26062

Query: 1526  KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH 1584
             K+T+                        +D  ++    +V  Q + P I + +      +
Sbjct: 26063 KSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKDQLEAPEINMKDFQHNTAY 26122

Query: 1585  -KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
              K G    +   + G P P+V   K+G  L++   +N      + +I ++E   S + +Y
Sbjct: 26123 VKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRY 26182

Query: 1644  TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
              I ASN+ GT+   V + V D+P    GPV M +I+ +SV+++W PP  DGG  +T Y +
Sbjct: 26183 DITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV 26242

Query: 1704  EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
              K E     WI+V+       T  I KLN   EY FR+ A+N  G SE ++S+ + +   
Sbjct: 26243 LKRETTTANWIEVSSAVARC-TIKIMKLNTGVEYQFRIKAENRFGISEHIDSQTVTVSLP 26301

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
               +P           +  ES+ + W     +GGS +  Y +++K      W+        
Sbjct: 26302 YTLP-VAPSQPWVSAVTKESIVVNWKEPSSDGGSHVFGYHLQMKDRNSILWQKVNTTVIR 26360

Query: 1823  XARIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                 +  ++N    Y+F++ A N  G      S D +       PP+  R   V++ T  
Sbjct: 26361 ATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPNSVR---VTDITKN 26417

Query: 1881  SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
             S++L W +P  +GGS IT Y+IE K      W+K      +  +  +  + + +   FR+
Sbjct: 26418 SISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRV 26477

Query: 1941  SAENTVG-VSLPTE 1953
              A+N VG VS P+E
Sbjct: 26478 MAKNAVGSVSNPSE 26491



 Score =  246 bits (603), Expect = 4e-63
 Identities = 177/692 (25%), Positives = 307/692 (44%), Gaps = 33/692 (4%)

Query: 1295  REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
             RE +   G+ + ++   +  P P   W  N   +      + S    +  L ++    TD
Sbjct: 16895 RELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETS--GTTTKLEMRYCNRTD 16952

Query: 1355  AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
              G Y L +EN  G       V +LDKP P     + ++ S S  + W +PE+ G + I  
Sbjct: 16953 CGDYTLTVENPAGSKIATCTVLVLDKPGPVQHLRVSDVRSDSAQLSWKDPEDNGGARITN 17012

Query: 1415  YVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             +VVE ++  + +W+ + + +K ++ + ++L   +SY FR  A N+   S+  ETT+  K 
Sbjct: 17013 FVVEKKDAASPQWVPICSSSKKRSMMAKHLIEGTSYMFRVAAENQFGRSEYVETTKAIKA 17072

Query: 1474  IKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGKK----LK 1523
             +    +  P   K L ++  +  E + L   +    GG  +    V +  +G+K     K
Sbjct: 17073 MNP--LFPPGPPKDLHHVDADKTE-VWLQWNWPDRTGGSDITGFLVEYQEEGEKDWIVFK 17129

Query: 1524  TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583
             T      +                   I  +     +T+  V  Q+K V  I   D+K  
Sbjct: 17130 TVSIPECHVTGLEEGKTYRFRVKTENAIGLS---RPDTTVPVLCQEKLVPPIVEVDVKLI 17186

Query: 1584  H----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                  K G    + A++ G+P P   W  +G +++++    I T   ++V+ I +  R+H
Sbjct: 17187 EGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKIDTDNFSTVLSIADCTRNH 17246

Query: 1640  SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             +  Y +  SN+AG+ +V + + V D P+ P GPV + E++ +S+ I+W+PP DDGG  + 
Sbjct: 17247 TGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILEVTPDSMVIDWRPPKDDGGSPVM 17306

Query: 1700  KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
              Y +EK E +   W  V+          I +L +  EY+ R+ A+N +G   ALES P V
Sbjct: 17307 NYIVEKRESNKETWGGVSSGSTSTRLK-ISRLQQGVEYVVRIRAENKMGIGAALESAPTV 17365

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX 1819
              +   + P           +  +++ + W     +GGSPI  Y +E + +G KW      
Sbjct: 17366 ARHQFEAPG-HPGKPVASDLSEDALTLGWTMPLFDGGSPISGYIIERRHKGGKWIRVNKT 17424

Query: 1820  XXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                  R + L +     Y+FR++A N  G S P    D     + +T P  P N  V + 
Sbjct: 17425 PCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSPVSDPAKPCRPITVPGPPVNPKVKDY 17484

Query: 1878  TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC---IENIKEKD 1934
             +     L W +P  +GGSP+  YI+E +   G  W K+      + + C   ++ + E  
Sbjct: 17485 SCTYADLVWIKPTKDGGSPVLGYIVECQK-GGAEWEKVNK--DDLIKQCAYRVKGLTEDT 17541

Query: 1935  EIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
             E  FR+ A N +G     E     + K   +P
Sbjct: 17542 EYRFRVKAVNMIGEGETREIPESVIAKDIIIP 17573



 Score =  241 bits (590), Expect = 1e-61
 Identities = 252/1059 (23%), Positives = 416/1059 (39%), Gaps = 69/1059 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F +K     V    D+ L+C L       I+W+    EI   E++ ++ E+      
Sbjct: 5549 PPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQT---- 5604

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +V+ I++V+    G YT  A N  G      VL +K    EP  + E  KS+ V   +  
Sbjct: 5605 AVIYISSVQLKHGGKYTCHAQNEAGSQKCTAVLTVK----EPANITEQAKSVSVTVRDPA 5660

Query: 753  ILSAQVVGNPRPTITWCKN-NKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENS 810
             L  +  G       W K+ N+       K    DT SI  +   +  D G YT +  N 
Sbjct: 5661 TLECRYSGTKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSND 5720

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRN 869
             G +   AV+TV +   +    P F  + +E T   KG+   +  +    +P ++TW++ 
Sbjct: 5721 AGRSSCEAVVTVLDQIIK----PSFTRKLKE-TESIKGSFTQLECLVSGSLPINVTWFKE 5775

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            N+ I   E     F      L I+ +DS  DSG+Y C+A N AG        T+ V++  
Sbjct: 5776 NKEIEADEKHKCIFFENAASLEISRLDSS-DSGNYTCIAKNQAGSDQCSG--TLKVKEPP 5832

Query: 930  FVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             +    +S +   G  V      S T  ++  W+ + KE+S      + +          
Sbjct: 5833 SIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELF 5892

Query: 988  XXXXXDVGVIKCIVKDQETS----TMLVVKETIPEFIRKLQDFEV-KEKDVAILEVEIN- 1041
                 D G   C V +   S      L VKE  P+F RK +   V K   + + E +I  
Sbjct: 5893 FAKPSDSGQYVCEVSNDVGSDSCQATLFVKEP-PKFTRKPEKITVVKPSQLVVFECQITG 5951

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097
            +   D  W +DG  I P  +KY       + +L I ++ + D G Y C  R+E    SC+
Sbjct: 5952 TPEIDTYWFKDGNDISPS-DKYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCS 6010

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFS-NHIQL 1154
             ++ V E PP ++  L   +V  G+ A FE  L KG A   V W KD  +I+ S  H+ L
Sbjct: 6011 MDLRVKE-PPVLVKPLSPLEVVNGSNAYFEC-LVKGTAPFEVTWEKDSKDIKSSLKHVIL 6068

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
              +     L +  CD  D GEY C    EVG+    + L+++EP  +F  R+   + V  
Sbjct: 6069 QKNDSIITLDVQKCDALDVGEYQCIVANEVGSCSSQSTLSIKEPP-SFVERIENVVTVLG 6127

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                +  V      L + W K +S I +        +    TL I  C      +YTC  
Sbjct: 6128 KMVEFKCVVRGSPPLSIQWQKDESWILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQA 6187

Query: 1271 LDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-II 1328
            ++     K     VV+ PP+I++      +  G  V+        P+   +W  + K +I
Sbjct: 6188 MNEAGQEKCFSTLVVQEPPQIIEKPEVINVTAGDPVSFECKVSGTPELKVKWSKDGKEVI 6247

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
               +H+   I++ S  L ++ V+  D G Y   + N+      ++ + +L++  PP    
Sbjct: 6248 PSRQHSLSYINNVS-QLKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPP---- 6302

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
                  S I    +  E  G +  I   +      T EW         +T  + L+  +S
Sbjct: 6303 ------SFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKDGTKLSGRTKHKILQDENS 6356

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
                   + + D    + T       K    +     +  ++    PN  +     F G 
Sbjct: 6357 VSLDIECLEKAD----TGTYTCKLANKAGSCECSGTLRVKESQAVIPNTTVRFKGSFKGT 6412

Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            P   V W++D  +L    + +                     +  +  G    SC +   
Sbjct: 6413 PPFTVKWFKDDTELICGPSCFTGLEGLSCFLDLF-------AVGISHSGTY--SCQISND 6463

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
             +P   +      +  K+G+   +   + G  P  + WYKN   L +     +T     +
Sbjct: 6464 AEPPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISWYKNDAILSDGGNLRMTFDNSVA 6523

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            V+ I       +  YT EA N AGT S    L + + PS
Sbjct: 6524 VLEISTSSFDDNGVYTCEAQNDAGTKSCSTALTIKEPPS 6562



 Score =  237 bits (581), Expect = 2e-60
 Identities = 258/1102 (23%), Positives = 449/1102 (40%), Gaps = 69/1102 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P+F K  ++  V  G+ + LEC++       I W+  G+++    +  +A E  +    +
Sbjct: 4803 PSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFEEKI----A 4858

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESV 752
             L I   K    GTYT  A N  G +S    + ++    EPP  ++ L+  I+ +QG S 
Sbjct: 4859 CLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQ----EPPVFVKRLEPKILWKQGMSS 4914

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810
             LS  V G+P   +TW  N+KP+ +    K    T+  T+ +      D G YT +  N 
Sbjct: 4915 RLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNE 4974

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G    S+ +TV+EP       P F    + + V +  T  L   +T      ITW+++ 
Sbjct: 4975 AGCESCSSQVTVKEP-------PAFKKELRLVEVVKGCTAHLECEMTGTAPFEITWFKDK 5027

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +S S+T       E    +        D GDY+C  SN  GK +  A   +  +  +F
Sbjct: 5028 NPVS-SDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLK-DPPSF 5085

Query: 931  VKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
            VK ++ +     G  V L+   + S  ++ +W+ + + +   D       E         
Sbjct: 5086 VKKVENTTAVL-GSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAIS 5144

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVEIN-SE 1043
                   G   C  +++          T+ E   F+ K     V   D A LE +++ S 
Sbjct: 5145 NVAINHGGKYTCQAENEAGKQKCEATVTVQEPARFVEKPPCISVTAGDSATLECKVSGSP 5204

Query: 1044 TADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYI--RNTSVHDEGEYSCILRDESCTAEV 1100
               V W +DG E+   +K K  F++   + K+    R  S   + E S  +  E C+  +
Sbjct: 5205 DLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSI 5264

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDG 1158
             V+E PP    + Q+Q V  G         T G A  +++WF++  E+       +  + 
Sbjct: 5265 NVLE-PPVFSLKPQSQDVIPGTTVVLTAAFT-GTAPFMIKWFREDKEMLTGGTCFIKKET 5322

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
                L+++      + +Y+C+V N      CTA L V+EP   F ++L    LV   + A
Sbjct: 5323 NSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPP-KFVMKLDLTKLVLNGSLA 5381

Query: 1215 YLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLD 1272
             L  ++     + + WYK ++ I   +K+ +       TL I  C  +D  +Y C    D
Sbjct: 5382 TLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQASSD 5441

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            A S     +  V+ PP+ V       I +G+DV L                +SK I+  +
Sbjct: 5442 AGSDRCSCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDR 5501

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
                S+    A+L I K E  DAG Y+  + N  G    +  VT+ + PS      + ++
Sbjct: 5502 RHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPS-----FVQKM 5556

Query: 1393 DSSSINICWDEPENT---GNSTI-IYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNS 1447
            D++++ +  D        G+  + I ++ +  EI  +E + +    +T    I +++   
Sbjct: 5557 DNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLKH 5616

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
              ++  +A NE      S+       +KE       + +  K+++    +   L C + G
Sbjct: 5617 GGKYTCHAQNEA----GSQKCTAVLTVKEPA----NITEQAKSVSVTVRDPATLECRYSG 5668

Query: 1508 VPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
                K  W +DG +L + +     + +                 Y     ND G      
Sbjct: 5669 TKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEA 5728

Query: 1564 VVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
            VV +  + +       +K+   + G    +  ++ G  P  V W+K   ++E D+++   
Sbjct: 5729 VVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCI 5788

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEG-PVIMREI 1678
              E  + + I  L  S S  YT  A N AG+     TLKV + PS   KPE   VI    
Sbjct: 5789 FFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPSIIEKPESQDVIPGSK 5848

Query: 1679 SRESVTIEWKPPLDDGGLELTK 1700
             + +V +   PPL     + TK
Sbjct: 5849 VQFNVLLSGTPPLTINWFKDTK 5870



 Score =  237 bits (579), Expect = 3e-60
 Identities = 184/721 (25%), Positives = 307/721 (42%), Gaps = 37/721 (5%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTS 1439
             P PP      +  +S I + W+ P+  G + I  Y+V+  +  T +W    + + + +  
Sbjct: 13303 PDPPENLKWRDKSASKIFLSWEPPKWDGGTPIKGYIVDKCQRGTDKWEPCGDPMPELKFE 13362

Query: 1440  IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPN 1496
             +  L     Y +R  A+N++  S   ++T+  +++     + P ++   K L  +T +  
Sbjct: 13363 VTGLIEGQWYAYRVRALNKLGASKPCKSTD--EILAVDPKEPPEIQLDAKLLAGLTAKAG 13420

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIA 1552
               IEL     G P+PKV W +    LK        T                   Y   A
Sbjct: 13421 TKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKRDDTATYIIEA 13480

Query: 1553  FNDHGEVETSCVVGIQQKP-------VITISNEDI----KQKHKVGDEWLVTAVIEGIPP 1601
              N  G    +  V I  KP       +  I+NE            G   +   ++E    
Sbjct: 13481 VNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNYIVERKAV 13540

Query: 1602  PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
                IWYK  + ++       TT + T ++  KE      ++        A  + + +   
Sbjct: 13541 DSEIWYKLSSTVKQ------TTYKATKLVAFKEYIFRVYAENQFGIGAPAEHAPI-IARY 13593

Query: 1662  VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
              +D P  P   +   +I++++VT+ W  P +DGG  +T Y +E++EPD+++WI+   +  
Sbjct: 13594 PFDTPGPPY-KLEPSDIAKDAVTLSWYEPDEDGGSPITGYWVERYEPDHDKWIRCNKLPI 13652

Query: 1722  DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780
                 + ++ L    +Y FRV+A+N  G  + + E++ I+IK  +D P           + 
Sbjct: 13653 RDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPID-PPWAPGKPTVKDVA 13711

Query: 1781  NESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQK-LSINTTYQFR 1838
               S ++ W   E +GG+ I  Y VE+ + G  +W              K L     Y FR
Sbjct: 13712 KTSAFLQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSLEHFLKGLMEKQEYSFR 13771

Query: 1839  IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
             + A N  G S P    D +   + L PPS PR  +V  S+  S  LKWT PE +GGSPIT
Sbjct: 13772 VRAVNVAGESEPSEPSDPVLCKERLNPPSPPRWLLVVSSSRNSAELKWTAPERDGGSPIT 13831

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             NYI+E + V+ K W  + T    + ++ +  + E    +FR++AEN VG S   E +   
Sbjct: 13832 NYIVEKRDVRRKGWQAVDTTVKEL-KYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSV 13890

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
             L K       P   L I  V    V   W  P+ DGG P+L Y I  ++   T W++ GK
Sbjct: 13891 LAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKSGK 13950

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078
                    + + D+ E      ++ A NE G+  P    EP  ++  E       P ++  
Sbjct: 13951 TSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHP---SEPTDIVVIEDPTGPPSPPQELH 14007

Query: 2079  V 2079
             +
Sbjct: 14008 I 14008



 Score =  236 bits (578), Expect = 4e-60
 Identities = 267/1198 (22%), Positives = 479/1198 (39%), Gaps = 99/1198 (8%)

Query: 510  PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P+FV++L PK     G + +  C V+G P   +TWF     +  S+  ++ +   N ATL
Sbjct: 4896 PVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKT-NQATL 4954

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             I ++   D+G +TC             E++ EA      S++TV               
Sbjct: 4955 EIIDLSESDSGNYTC-------------EVMNEAGCESCSSQVTVKE------------- 4988

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                PP F K+ +   V +G    LEC +      +I W FK +  V  +     +  + 
Sbjct: 4989 ----PPAFKKELRLVEVVKGCTAHLECEMTGTAPFEITW-FKDKNPVSSDTKYNIVSKET 5043

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
              Y   L+I   +    G Y     N  G+ +   V K+K    +PP  ++ +++     
Sbjct: 5044 AAY---LEIKTFESADVGDYQCCISNDVGKITTKAVAKLK----DPPSFVKKVENTTAVL 5096

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKV--KDEGVYTL 805
            G +V L   + G+   T+ W K+ + V+   P  +    ++I +L    V     G YT 
Sbjct: 5097 GSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTC 5156

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            +AEN  G  +  A +TV+EP     +PP        +T  +  T++   +V+ +P   + 
Sbjct: 5157 QAENEAGKQKCEATVTVQEPARFVEKPPCI-----SVTAGDSATLE--CKVSGSPDLKVK 5209

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W+++ + ++        F  EN+ ++        DS +YK   SN  GK      + +  
Sbjct: 5210 WFKDGKEMAGGRKYKITFK-ENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINVLE 5268

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXX 983
              V  +K   +S +   G TV+L    + T     KW+   KE+       I +E     
Sbjct: 5269 PPVFSLK--PQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSS 5326

Query: 984  XXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEV 1038
                           C V +       +  L VKE  P+F+ KL   + V    +A LE 
Sbjct: 5327 LELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEP-PKFVMKLDLTKLVLNGSLATLEC 5385

Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095
            ++  S    + W ++   I    +KY       +  L I +  V D G+Y C    ++  
Sbjct: 5386 KVAGSPEISIRWYKNETEIG-SDDKYQMAFTDSVATLRISSCCVEDSGDYICQASSDAGS 5444

Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152
              C+  VTV E PPE +   +++++ KG     E  ++      +  FKD  +I+     
Sbjct: 5445 DRCSCLVTVKE-PPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDRRH 5503

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPEFILV 1208
             +++      L+I   +  DAG+Y C VGN    + C  ++T++EP  +F  ++    ++
Sbjct: 5504 IISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPP-SFVQKMDNTNVL 5562

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
             A   +   V      + ++W K    I+++E   +  + +   + I         +YTC
Sbjct: 5563 LAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLKHGGKYTC 5622

Query: 1269 VLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
               +   + K   V  V+ P  I +  +   +      TL   Y        +W+ +   
Sbjct: 5623 HAQNEAGSQKCTAVLTVKEPANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNE 5682

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +   +  K      S+ L I   E +DAG Y   + N+ G +  E  VT+LD+   P   
Sbjct: 5683 LTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFT 5742

Query: 1388 NILEIDSSSINICWDEPENTGNSTI---IYYVVEYQEIDTTE---WISVKNITKTQTSIQ 1441
              L+ ++ SI   + + E   + ++   + +  E +EI+  E    I  +N    +  I 
Sbjct: 5743 RKLK-ETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLE--IS 5799

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
             L ++ S  +   A N+      S T +    +KE       +EKP ++    P   ++ 
Sbjct: 5800 RLDSSDSGNYTCIAKNQAGSDQCSGTLK----VKEPP---SIIEKP-ESQDVIPGSKVQF 5851

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX--XXXXXYKCIAFNDHG 1557
              +  G P   + W++D K++ +    +  +N                  Y C   ND G
Sbjct: 5852 NVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVG 5911

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
                   + +++ P  T   E I    K     +    I G P  +  W+K+GN +    
Sbjct: 5912 SDSCQATLFVKEPPKFTRKPEKITVV-KPSQLVVFECQITGTPEIDTYWFKDGNDISPSD 5970

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP--SKPEGPV 1673
            +Y +T  +  + + I       S  Y  EA N AG+ S  + L+V + P   KP  P+
Sbjct: 5971 KYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSPL 6028



 Score =  234 bits (573), Expect = 2e-59
 Identities = 200/756 (26%), Positives = 322/756 (42%), Gaps = 47/756 (6%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284
             V W K    +++T +       +   L++++ T DD  +YT  + ++  ++T  + V V+
Sbjct: 21815 VVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVL 21874

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSIDSKS 1342
             + P          +I+  +  ++ + +Q  P+      +N+ I++K     T   I S +
Sbjct: 21875 DKPGPPTG---PIKIEEVTADSVTLSWQP-PEYEGGCSINNYIVEKRDTSTTNWQIVSAT 21930

Query: 1343  ASLTIKKVENTDAGI-YKLRL--ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDS 1394
              + T  K      G  Y+ R+  EN  G + V ++  ++ +     P PPG P +     
Sbjct: 21931 VARTTTKAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSATK 21990

Query: 1395  SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452
              S+ + W++P + G S I+ Y +E +E ++  W+      I  T+  I  L+    Y FR
Sbjct: 21991 ESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFR 22050

Query: 1453  AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQ 1510
              YA N V +S AS+ +E    I+  +       KP   I    +  +  T     GG+  
Sbjct: 22051 VYAENIVGLSKASKVSE----IQVARDPCDPPGKPEAVIVKRSSVTLRWTPPQFDGGI-- 22104

Query: 1511  PKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG--EVETS 1562
              K+T Y   KK     +  KA++ N                Y  + IA N  G   V + 
Sbjct: 22105 -KITGYVVEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSD 22163

Query: 1563  CVVGIQQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
                 I  K  +     D+  K+        G+ + + A I G P P V W K+G +L N 
Sbjct: 22164 STGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELTNT 22223

Query: 1617  KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
                 I   + T+ + +KE  R    +YT+   N  G  SV + +KV D+P  P+GP+ + 
Sbjct: 22224 ARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEKSVIINVKVLDRPGPPDGPISIY 22283

Query: 1677  EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
              ++ E   I WK PL DGG E++ Y +E+ E     W  V ++        I KL    E
Sbjct: 22284 GVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLVW-TVVELKVQTLNLKITKLLPGNE 22342

Query: 1737  YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
             Y+FRVI  N  G  E LES+P++       P           I  +S+ ITW     +GG
Sbjct: 22343 YIFRVIPVNKYGIGEPLESDPVIAANPFVTPE-APSNVEVSNITKDSMVITWERPTNDGG 22401

Query: 1797  SPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTS 1853
             S I  Y VE + +EG +W           R +   +    +Y+FR+ A N  G   P   
Sbjct: 22402 SAITGYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLLEMRSYEFRVSAENAAGVGKPSPP 22461

Query: 1854  DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
                      +  P  P N  V+  +  SV L W++P  +GG  I +YI+E   V    W 
Sbjct: 22462 TVYFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWV 22521

Query: 1914  KIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGV 1948
                   G        + + EK E  FRI A N +GV
Sbjct: 22522 MCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGV 22557



 Score =  234 bits (573), Expect = 2e-59
 Identities = 195/769 (25%), Positives = 337/769 (43%), Gaps = 49/769 (6%)

Query: 1216  LTVEIPDE---TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             L VEIP +   T  + W K    +++T +  + S      L I++   +D  +YT    +
Sbjct: 23964 LKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATN 24023

Query: 1273  AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
                T   +V ++    K        +I   S   +++ ++  P       +N+ +++K  
Sbjct: 24024 NIGTVTEEVAIIILD-KPGPPTGPVKIDEVSATYVVISWEP-PVYTGGCQINNYVVEKRD 24081

Query: 1333  HTKPSIDSKSASL---TIKKVENTDAGIYKLRL--ENNCGHA-DVEMNVTILD----KPS 1382
              T  +  + SA++   TIK  +      Y+ R+  EN  G +  ++    ++     +P+
Sbjct: 24082 TTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTEPA 24141

Query: 1383  PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSI 1440
              PG P +  +    + I W  P N G S II Y +E +E ++  W  +    IT T+   
Sbjct: 24142 APGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTRLRT 24201

Query: 1441  QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT---- 1493
               L+    Y +R +A N   IS +S+ +E   V+       P   + +   +N+ T    
Sbjct: 24202 NGLEEGIEYEYRVFAENIAGISPSSKVSE--SVVARDPCDPPGTPEAIVITRNLITLQWT 24259

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCI 1551
             +P  D   + I G + + K     DG+ +K   A++ N                Y  + I
Sbjct: 24260 KPQYDGG-SVITGYIIERKKL--PDGRWMK---ASFTNIIDTQFTITGLHEEQRYEFRVI 24313

Query: 1552  AFNDHGEV----ETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPE 1603
             A N  G +    E++  +  Q +      + D + K     K GD + + + I G P P+
Sbjct: 24314 ARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPD 24373

Query: 1604  VIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             ++W K+G ++++      I +    +V+ +K+  R     + +  SN  GT  V + +KV
Sbjct: 24374 IVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGGTKQVPINVKV 24433

Query: 1663  YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
              D+P  P+GP+ +  ++ E   + W  P  DGG  ++ Y IEK E     W  V +    
Sbjct: 24434 LDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSW-TVVEPKIQ 24492

Query: 1723  VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
               +Y + KL    EY+FRV+A N  G  E LESEP++ K   + P           I  +
Sbjct: 24493 AISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESEPVLAKNPFNKPG-PPSTPEASAITRD 24551

Query: 1783  SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQK--LSINTTYQFRI 1839
             S+ +TW   E +GGS I  + +E + +EG +W           R +   L+    Y+FR+
Sbjct: 24552 SIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLNDLRFRATGLTEGHFYEFRV 24611

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
              A N  G   P    +         PP  P N  V++ +S +V+L W+ P  +GG+P++ 
Sbjct: 24612 SAENAAGVGTPSEPSEYYKACDATYPPGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSG 24671

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVG 1947
             YI+E K +    WT      G    H  ++ +KE  E  FRI A N  G
Sbjct: 24672 YIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEG 24720



 Score =  234 bits (572), Expect = 2e-59
 Identities = 183/680 (26%), Positives = 283/680 (41%), Gaps = 39/680 (5%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             +K G+ + + V  +  P P   W   +  +K   H   +       + I +    DAG Y
Sbjct: 20424 VKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTT--ESYTLVVIPECTRYDAGKY 20481

Query: 1359  KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
              L LEN  G     +NV ++D P PP      EI   SI + W+ P   G S I  Y++E
Sbjct: 20482 VLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHSITLQWEIPLIDGGSKIKNYIIE 20541

Query: 1419  YQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
              +E     + +   N  K    I +L+  + Y FR  A NE+ I + +ET +  +  +  
Sbjct: 20542 KREATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIRASQAP 20601

Query: 1478  KIQSPTVEKPLKNIT-----TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKAT 1528
                   +   +   T     T+P  D       GG    ++T Y    +LK     A  T
Sbjct: 20602 SAPDDLIVTDVSKDTATLAWTKPKHD-------GG---SRITGYVIEAQLKDSDQWAHVT 20651

Query: 1529  YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQKH- 1584
                                ++  A N  G  E   +  VV  +Q          I QK  
Sbjct: 20652 TIKALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTV 20711

Query: 1585  --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
               K GD   V   + G P P V+W K   +L+  +  NI     ++++ I E+KR    +
Sbjct: 20712 VAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQ 20771

Query: 1643  YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
             Y++   N  GT +  +T++V+D P  P GP+ + E+S + V I W+ P +DGG+ +  Y 
Sbjct: 20772 YSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNYI 20831

Query: 1703  IEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
             +E  E     W+++ A V R   T+   +L    EY FRV AQN  G    + S P+V  
Sbjct: 20832 VEMRETTGTSWMELAATVIR--TTFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAA 20889

Query: 1762  TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
                DVP              +++ I+W     +GGSPI+ Y +E K++    W+      
Sbjct: 20890 YPFDVPG-QPGIPQIVAFTKDAMTISWNEPSSDGGSPILGYHIERKEKNSILWQRISKAV 20948

Query: 1821  XXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   +   L     Y+FR+ A N  G S      +       + PPSQP   V    T
Sbjct: 20949 VVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSEMTYALDPVDPPSQP---VALNIT 21005

Query: 1879  SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
                VTL+WT+PE +GG  IT Y +E + +    W K            +  + E     F
Sbjct: 21006 RHEVTLQWTKPEGDGGFSITGYTVEKRELPNGRWLKANFSNILETNFTVSGLTEDVSYEF 21065

Query: 1939  RISAENTVG-VSLPTESQSV 1957
             R+ A N+ G VS P++   V
Sbjct: 21066 RVLARNSAGAVSKPSKPSEV 21085



 Score =  232 bits (567), Expect = 9e-59
 Identities = 199/758 (26%), Positives = 325/758 (42%), Gaps = 45/758 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVV 1284
             V W K+   ++ T++  + +      L I +    D  +Y+    +   T    + V+V 
Sbjct: 20733 VVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQYSMTGKNILGTVTENITVQVH 20792

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             + P          ++   S   +L+ ++A P+ +    +N+ I++  + T  S    +A+
Sbjct: 20793 DIPGPPTG---PIKLDEVSCDYVLISWEA-PENDGGVPINNYIVEMRETTGTSWMELAAT 20848

Query: 1345  L--TIKKVENTDAGI---YKLRLENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDS 1394
             +  T  K      GI   ++++ +N  G      +  ++     D P  PG P I+    
Sbjct: 20849 VIRTTFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAAYPFDVPGQPGIPQIVAFTK 20908

Query: 1395  SSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFR 1452
              ++ I W+EP + G S I+ Y +E +E ++  W  IS   +         L    +Y FR
Sbjct: 20909 DAMTISWNEPSSDGGSPILGYHIERKEKNSILWQRISKAVVVGNMFKSSGLMDGIAYEFR 20968

Query: 1453  AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--IT---TEPNEDIELTCIFGG 1507
               A N   +S AS+ +E    +      S  V   +    +T   T+P  D   +     
Sbjct: 20969 VIAENLAGLSKASKPSEMTYALDPVDPPSQPVALNITRHEVTLQWTKPEGDGGFSITGYT 21028

Query: 1508  VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETS--- 1562
             V + ++    +G+ LK   A + N                Y  + +A N  G V      
Sbjct: 21029 VEKRELP---NGRWLK---ANFSNILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKP 21082

Query: 1563  -----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
                  C   I++  +   ++       K GD + + A + G P P ++W K+G +LE+  
Sbjct: 21083 SEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTGRPIPSIVWTKDGKELEDTA 21142

Query: 1618  EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
             +  I T +  S +  K+  R     YT+ ASN  G +     +KV D+P  PEGP+ + +
Sbjct: 21143 KMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGGFAKFVFNVKVLDRPGPPEGPLHVTD 21202

Query: 1678  ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
             ++ E   + W PPL DGG ++  Y I++ E     W  VA  D  V  Y + KL +  EY
Sbjct: 21203 MTVEKCVLSWLPPLHDGGGKIEYYIIQRRETSRLTWTNVA-TDLQVNRYKVTKLLKGNEY 21261

Query: 1738  MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             +FRV+A N  G  E LESEP  + T   VPS          I  +S+ + W   E NGGS
Sbjct: 21262 IFRVMAVNKYGVGEPLESEP-AVATNPYVPSDPPQAPEVTAITKDSMVVCWGHPEYNGGS 21320

Query: 1798  PIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
              I  Y +E + + G +W           R  +  L+    Y++RI A N  G S P  S 
Sbjct: 21321 SINTYIIERRDKTGLRWVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPSS 21380

Query: 1855  DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
                    T+  P  P N  V ++T  S+T+ W +P  +GGS IT YI+E    +   WT 
Sbjct: 21381 PFYKACDTIFQPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVETCLPEEDEWTI 21440

Query: 1915  IVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
             +  + G +     I N+ E  E    ISA N  GV  P
Sbjct: 21441 VTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEP 21478



 Score =  229 bits (561), Expect = 5e-58
 Identities = 229/896 (25%), Positives = 368/896 (41%), Gaps = 57/896 (6%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249
             +E P I+    L + I V A     L V I    T +V W K +  I +  +  + S   
Sbjct: 22573 LEAPDIDLDADLRKMITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFT 22632

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               +L+I      D  +YT  L +A  T    + V V++ P    D    +R+K  +  ++
Sbjct: 22633 --SLVIENVNRFDSGKYTLTLENASGTKSAFISVRVLDTP----DMPANFRVKEITKNSV 22686

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK-KVENTDAG-IYKLRL--E 1363
              + ++  P  +    + S I++K + T+    + +    +  K+E  + G IY  R+  E
Sbjct: 22687 TLTWEP-PLLDGGAKIKSYIVEKRESTRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAE 22745

Query: 1364  NNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
             N  G    A+    + I + P PPGK +++++   S+++ W++PE+ G S I YY VE Q
Sbjct: 22746 NEHGIGLPAETPEPLKISEVPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQ 22805

Query: 1421  EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
               D  +W     +    T + NL     Y FR  AVN+   SD         V K+  I+
Sbjct: 22806 AKDQDKWSLCAQVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPV-VAKDLAIE 22864

Query: 1481  SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXX 1536
              PTV   L   + +   D+++     G P+P +TW +DG  LK       A   +     
Sbjct: 22865 -PTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLT 22923

Query: 1537  XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTA 1594
                        Y  +  N  G+ E +  + I +KP        I +     +   W    
Sbjct: 22924 IKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSAESITLSWDPPT 22983

Query: 1595  VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
                G      I  K      N    + T    T  +++  LK     ++ I A N  G S
Sbjct: 22984 YTGGCQISNYIVQKRDTTTTNWVVVSATVARTT--LKVGNLKTGAEYQFRIFAENRYGKS 23041

Query: 1655  ----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
                 S  V  +   K   P G   +   ++ES+ +EW  P+ DGG  +  Y +E+ E ++
Sbjct: 23042 YGIDSDPVLAQYPFKEPGPPGTPFVSAFNKESMVVEWHKPVSDGGSAILGYHLERKEKNS 23101

Query: 1711  NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSX 1769
               W K+  +      Y    L E  EY FRV A+N VG  +  + SE  + +   D P  
Sbjct: 23102 ILWTKINKILIQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSEGCIARDPCDPPG- 23160

Query: 1770  XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RI 1826
                      +   SV + W P E +GGS +  Y VE +   EG+  K            +
Sbjct: 23161 ---TPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVEKRDLPEGRWMKASFANILETEFTV 23217

Query: 1827  QKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
               L  +  Y FR+ ARN  G+ S P  S   +T    + PP+    + V+   S+ +T+ 
Sbjct: 23218 TGLIEDCKYDFRVIARNGAGSVSRPSESTGSVTAKDEVEPPT----YEVASEYSQILTVN 23273

Query: 1886  WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII----FRI- 1940
               +  S   S +   I   +  KG      V V  S     I+N   K  ++     RI 
Sbjct: 23274 AGDTFSLEASVLGKPIPAMQWFKGD-----VEVENSARAE-IKNTDFKAVLVVKDAIRID 23327

Query: 1941  SAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
               + T+ +S    S+SV    +    P PP  PL +  V +     SW  P  DGG+ + 
Sbjct: 23328 GGQYTLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVTNEKCSLSWLPPRHDGGSSIS 23387

Query: 2000  GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              Y I  R+ ++  W  V   D     F +  L + + Y+ R+ A N+ G+ EPLES
Sbjct: 23388 YYVIQKRETSRLAWTVVSG-DCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEPLES 23442



 Score =  229 bits (560), Expect = 6e-58
 Identities = 182/697 (26%), Positives = 296/697 (42%), Gaps = 34/697 (4%)

Query: 1282  EVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPS 1337
             EV E P   +D    +   ++ G  + L    +  P P   W  I    +I++  H    
Sbjct: 18269 EVHEHPEIDLDASLRKGLSVRAGCPIRLFATIRGRPAPKVTWKRIGVDNVIRR-GHVD-Q 18326

Query: 1338  IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
             ID+ +  L I +    D+G Y L L N  G   V + V +LD P P G  +  +I  +S 
Sbjct: 18327 IDTMTF-LVIPESSREDSGKYSLTLSNPSGEKAVFVRVKVLDTPGPVGGLDATDITKTSC 18385

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAV 1456
              + W  PEN G S I+ Y+VE +E+D   W +  N + KT   I NL     Y FR  AV
Sbjct: 18386 QLAWLPPENDGGSPILNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAV 18445

Query: 1457  NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK---V 1513
             N+  I    ++ + Y          P  +  +  IT        L  +  G  +     V
Sbjct: 18446 NKYGIGLPQDSPKSYLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIV 18505

Query: 1514  TWYRDGK-KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-----EVETSCVVGI 1567
              + +DG+ + K    +                   ++  A N  G     E E    V  
Sbjct: 18506 EYQQDGQPEDKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKE 18565

Query: 1568  Q-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
             Q   P I +S  D+    + G + +V A++ G P P   W +  + +       I     
Sbjct: 18566 QLMAPKIIVS--DVVTA-RAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPT 18622

Query: 1627  TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             TS++ +K++ R  S  Y++ A N+    +  + + + D P  P+GP+ + E+  ++ T+ 
Sbjct: 18623 TSLLMVKDVTRKDSGYYSLSAENSTAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLA 18682

Query: 1687  WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQN 1745
             W  P +DGG  +T Y +EK +     W+         +T C + KL    EY FRV A+N
Sbjct: 18683 WDTPAEDGGSNITNYIVEKCDVTRGDWVTAVSC---TKTSCRVGKLTCGKEYGFRVRAEN 18739

Query: 1746  PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
               G SE + SE ++ +   D PS          +  E V ++W     +GGS +  Y +E
Sbjct: 18740 RFGISEPIYSEKMIARHPFDPPS-EPLNCCVNKVSKEFVVLSWEKPVNDGGSALTGYFIE 18798

Query: 1806  IKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
              K+     W                 L     Y FR+ A N+ G   P    D IT    
Sbjct: 18799 RKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFRVSAVNKAGQGKPSKQTDFITARSP 18858

Query: 1863  LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
             + PP +P    + + T  SV+L W+ P+ +GGS +  Y +EF  +K   W ++ +   +V
Sbjct: 18859 VDPPGKPE---IIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNSQNV 18915

Query: 1923  --HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
                E+ +  ++E  +  FRI A+  + VS+P+E   V
Sbjct: 18916 PKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDV 18952



 Score =  229 bits (559), Expect = 8e-58
 Identities = 243/1084 (22%), Positives = 435/1084 (40%), Gaps = 68/1084 (6%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHM 690
            PP F +K P A+ V  G  + LEC++       I+W +K + I+ D  N+ +  ++ +  
Sbjct: 6466 PPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISW-YKNDAILSDGGNLRMTFDNSV-- 6522

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
              +VL+I+       G YT  A N  G  S    L IK    EPP   +    +   +G+
Sbjct: 6523 --AVLEISTSSFDDNGVYTCEAQNDAGTKSCSTALTIK----EPPSFYKLPTPVEGLKGK 6576

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
               L+ ++ G+    ITW K+ K +K        S+G + ++ IL   +  D G Y  KA
Sbjct: 6577 DASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEGCSATLHILG-LEASDAGEYECKA 6635

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N+ G       + + EP       P F+ +    T      + L+  V  +   +++W 
Sbjct: 6636 TNNVGSDLCQGSVKLREP-------PAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWV 6688

Query: 868  RNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            ++ + I+   E     F+   + L +   DS   +G Y C   N AG +   A +T+ +E
Sbjct: 6689 QDKDHILRDGENRKITFENNEVTLKVFKADSTT-AGKYTCQLKNDAGVAECTANLTV-LE 6746

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
                V     S     G+   LEC  S T  +  KW+ +  E+S     +I         
Sbjct: 6747 PAAIVDKTD-SISVTAGEAAALECTVSGTPELKPKWFKDGVELSSGKKYKITFSKMISSL 6805

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQDFE-VKEKDVAILE 1037
                    D G     +K++  S    ++ T+      P F RKL+D + +  K + +  
Sbjct: 6806 KLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDKIVPPLFSRKLKDTQSIVGKSMELDC 6865

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
                S    + W  +   I    N Y+     +   L +    + D G Y C   + +  
Sbjct: 6866 KASGSAPLTISWFHNEVEIMSGPN-YEITFTENTCTLKVPTLKLSDSGTYKCKAVNSAGA 6924

Query: 1098 AEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153
            AE +   VV+ PP  +T  Q  +   G   TF   +     + ++WF+   EI      +
Sbjct: 6925 AETSASLVVKEPPSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCE 6984

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209
            + + G    L++++ D   AGEY+C++    G   C   L V+E + +F  +L    +  
Sbjct: 6985 IALRGDTAILELHNIDKSHAGEYTCQIINDAGKENCPVNLFVKEAA-HFVKKLKNLSVEM 7043

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268
              +            + V W+K    I  + K+ + +      L      ++   +YTC 
Sbjct: 7044 GKSLILECTYAGSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCE 7103

Query: 1269 VLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            V  DA     +  V ++E PP  ++      +  G  V L       P+    W      
Sbjct: 7104 VSNDAGHDICEAAVSILE-PPFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGK 7162

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            ++     K       A L + KV  +D G Y  + EN+ G A    ++T+ D  +PP  P
Sbjct: 7163 VRSSPTCKMEFFKGIACLKLAKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFP 7222

Query: 1388 ----NILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDT-TEWISVKNITKTQTSIQ 1441
                +I++I+   +     E    G+S + + ++ + + + + +E+    +      +I 
Sbjct: 7223 KKITSIMQIEGQPVQF---ECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNSAVLNIA 7279

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
              +   S  +   A N V     S +      ++E +   P  +K L  +     + +EL
Sbjct: 7280 KGEMRHSGEYTCVATNSV----GSASCRAKLTLQEPRYP-PVFDKKLVPVDVSVGDTVEL 7334

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
             C   G    KVTW +D K ++T      +  EN                Y C A ND G
Sbjct: 7335 ECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVG 7394

Query: 1558 EVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            +   S  V ++++  P           +   G    +   + G  P  V WYK+G ++  
Sbjct: 7395 KDSCSTEVSVKERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFT 7454

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
               Y++T K   +V+ IK+ + S S  Y  +A+N AGT+S EV++ +  +   P   + +
Sbjct: 7455 SDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKATNEAGTASFEVSVHITAQKVPPSFDLPL 7514

Query: 1676 REIS 1679
            + ++
Sbjct: 7515 KPVT 7518



 Score =  227 bits (554), Expect = 3e-57
 Identities = 191/758 (25%), Positives = 317/758 (41%), Gaps = 37/758 (4%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
             +TW K  S ++ T +  +       TL I+  T +D   Y  V+ +     +  VE++  
Sbjct: 22896 ITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIIIL 22955

Query: 1287  PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSAS 1344
               K        RI   S  ++ + +   P       +++ I++K   T  +  + S + +
Sbjct: 22956 E-KPGPPTGPVRIDEVSAESITLSWDP-PTYTGGCQISNYIVQKRDTTTTNWVVVSATVA 23013

Query: 1345  LTIKKVENTDAGI-YKLRL--ENNCGHA-----DVEMNVTILDKPSPPGKPNILEIDSSS 1396
              T  KV N   G  Y+ R+  EN  G +     D  +      +P PPG P +   +  S
Sbjct: 23014 RTTLKVGNLKTGAEYQFRIFAENRYGKSYGIDSDPVLAQYPFKEPGPPGTPFVSAFNKES 23073

Query: 1397  INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--LKTNSSYRFRAY 1454
             + + W +P + G S I+ Y +E +E ++  W  +  I    T  +   L+    Y FR Y
Sbjct: 23074 MVVEWHKPVSDGGSAILGYHLERKEKNSILWTKINKILIQDTRYKTSPLEEGIEYEFRVY 23133

Query: 1455  AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT---CIFGGVPQP 1511
             A N V I   S+T+E    I       P    P+  I T  +  +  T      G +   
Sbjct: 23134 AENIVGIGKCSKTSE--GCIARDPCDPPGTPVPV--IVTRHSVKLRWTPPEYDGGSLVTG 23189

Query: 1512  KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE--TSCVVGI 1567
              V   RD  + +  KA++ N                Y  + IA N  G V   +     +
Sbjct: 23190 YVVEKRDLPEGRWMKASFANILETEFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTGSV 23249

Query: 1568  QQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               K  +     ++  ++        GD + + A + G P P + W+K   ++EN     I
Sbjct: 23250 TAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEI 23309

Query: 1622  TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
                +  +V+ +K+  R    +YT+  SN AG+ SV   ++V D+P  PEGP+ +  ++ E
Sbjct: 23310 KNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVTNE 23369

Query: 1682  SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
               ++ W PP  DGG  ++ Y I+K E     W  V+  D     + + KL +  EY+FRV
Sbjct: 23370 KCSLSWLPPRHDGGSSISYYVIQKRETSRLAWTVVSG-DCGATMFKVTKLLKGNEYIFRV 23428

Query: 1742  IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
             +A N  G  E LES  ++++     P           I  +S+ + W   E +GG+ I+ 
Sbjct: 23429 MAVNKYGVGEPLESRAVIMRNPFVAPG-PPQDLEITNISRDSMTVCWTRPESDGGNEIVG 23487

Query: 1802  YKVEIK-QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             Y VE + + G +W             R+  L+ +  Y+FR+ A N  G   P        
Sbjct: 23488 YIVEKRDRAGIRWTKCNKRRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPSQPTVYYK 23547

Query: 1859  IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVT 1917
                    P QP N  + ++T  SVT+ W+ P  +GG  I  Y++E      + W T    
Sbjct: 23548 ACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGYVVEISKADEEEWITCTPP 23607

Query: 1918  VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
              G +  +  I  + E  E   RI A N +GV  P   Q
Sbjct: 23608 TGLNDTKFSITKLTEHQEYKVRICALNKLGVGEPVPIQ 23645



 Score =  221 bits (541), Expect = 1e-55
 Identities = 193/772 (25%), Positives = 332/772 (43%), Gaps = 54/772 (6%)

Query: 1226  DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
             +VTW K    ++ T +  +++      + I+  T +D  +Y   L +       ++ V+ 
Sbjct: 25060 EVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFGVKSAEISVIV 25119

Query: 1286  F----PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
                  PP  +  E          ++L  D   +   +    +N+ +++K   T  +    
Sbjct: 25120 LDKPGPPGAIKVEEI----SADFISLSWDPPIY---DGGCQINNYVVEKRDTTTTAWQIV 25172

Query: 1342  SASL---TIKKVENTDAGIYKLRL--ENNCGHAD-VEMNVTILDKP-SPPGKPNILEID- 1393
             SA++   +IK    T    Y+ R+  EN  G +  ++    +   P +PPG P  L++  
Sbjct: 25173 SATVARTSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIVAQYPFTPPGPPTSLQVSH 25232

Query: 1394  --SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449
                S + + W+ P + G S I+ Y +E ++  +  W  +    IT+TQ  +  L+    Y
Sbjct: 25233 ATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNRGLITETQFKVTGLEEGLQY 25292

Query: 1450  RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGV 1508
             ++R YA N   I   ++  +    +      +P  +  + NIT T  +         GG 
Sbjct: 25293 QYRVYAENIAGIGPCTKACD---PVSARDPCAPPSQPRVMNITRTSVSLSWTKPEFDGGA 25349

Query: 1509  PQPKVTWY-------RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---- 1557
                KVT Y        DG+ LK    T                   ++ IA N  G    
Sbjct: 25350 ---KVTGYIVERSELPDGRWLK-CNFTNLQETYFDVTGLIEDQRYDFRIIAKNAAGLFSE 25405

Query: 1558  EVETSCVVGIQQK---PVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
               E++  V ++     P ITI ++ ++Q    K G+   + A I G P P + W K+G +
Sbjct: 25406 PSESTGPVTVKDDVDPPRITIEDK-LRQLVVIKAGEILRIDAEISGRPIPVISWAKDGKE 25464

Query: 1613  LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             +E    + I++   ++ + +++  R  S +Y +   N AGT S+ V  KV D+P    GP
Sbjct: 25465 IEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNCKVLDRPGPSSGP 25524

Query: 1673  VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732
             + +  ++ E  T+ W PP ++GG E+  Y +EK E     W  V   D    T  + KL 
Sbjct: 25525 LDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVY-ADMKATTCKVTKLL 25583

Query: 1733  ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
             +  EY+FRV   N  G  EALES+P        VP+          + +E++ I W    
Sbjct: 25584 KGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTVPA-APTDVEVTSVTSEAMTICWERPI 25642

Query: 1793  KNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSL 1849
              +GGS I  Y +E +++ G +W           R++   L     Y++R++A N  G S 
Sbjct: 25643 SDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSA 25702

Query: 1850  PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
             P            L  PS P    + +ST  SVTL W +P  +GGSP+T Y++E++    
Sbjct: 25703 PSVPCPLTKAEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEYRNTND 25762

Query: 1910  KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
               WT  V    S  E  +  +    E +F + + N +G S P+     ++ K
Sbjct: 25763 DDWTVGVNNTKST-EFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDPQVAK 25813



 Score =  220 bits (538), Expect = 3e-55
 Identities = 213/890 (23%), Positives = 373/890 (41%), Gaps = 68/890 (7%)

Query: 1276  TTKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
             T+++++E ++  PKI   +  +    ++ G+   +       P P   W  + K   + K
Sbjct: 15569 TSEVRIEDIKTAPKIFMDISADELLCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKK 15628

Query: 1333  ---HTKPSIDSKSAS------LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
                H  P +DS+  S      +T+     + +G Y +  +N  G   V + V +LD P  
Sbjct: 15629 DRLHILP-VDSQVESTDTTSVVTVPVSLRSHSGRYTITAKNKSGQKHVNVRVNVLDVPGA 15687

Query: 1384  PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQ 1441
             P +  + ++  +++ + W  P+N G   I  Y +E + ++   W +V N T    +  + 
Sbjct: 15688 PKELKVTDVTRTTMRLIWKLPDNDGGERIKSYFIEKKAVNGKAW-TVANATCASMAFVVS 15746

Query: 1442  NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIE 1500
             NL     Y FR  A N +     +ETTE   V     I  P     +K N+ T+    + 
Sbjct: 15747 NLLEGQDYFFRVRAENRLGFGPFTETTE--PVRARDPIYPPDPPTKVKINLVTK--NTVT 15802

Query: 1501  LTCI----FGGVPQ-----PKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXY 1548
             LT +     GG P       +++W   G + +T K   +                    +
Sbjct: 15803 LTWVPPKNDGGAPVKHYIIERLSWDTSGPQKETWKQCNKRDVEETTFIIEDLKEGGEYEF 15862

Query: 1549  KCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVI 1605
             +  A N+ G    S   G I  K      + D+++  +   G +  + A I+G P P ++
Sbjct: 15863 RVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGAEGFDVNIVARIQGCPFPSLV 15922

Query: 1606  WYKNGNKLENDK---EYN-----ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
             W+K      +DK   +Y+     + + EK S+  I++ KR  S+ YT+ A+N+ GT++  
Sbjct: 15923 WHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLF-IQQSKRDDSAMYTLTATNSLGTATKS 15981

Query: 1658  VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
             + L +  +P  P GP+ + E+  E + + W PP DDGG ++T Y +EK E +   W+ V+
Sbjct: 15982 IKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGGSKITNYVVEKREENRKTWVHVS 16041

Query: 1718  DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
                ++ + Y +Q+L E  EY FRV+AQN  G    L SEP   +     P          
Sbjct: 16042 SDPKECQ-YIVQRLTEGHEYEFRVMAQNKYGVGPPLYSEPEKARNLFTPPG--PPTPKVT 16098

Query: 1778  XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTT 1834
                  +V + W P   +GGS I  Y VE KQEG ++W+          +  +  L     
Sbjct: 16099 DCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGL 16158

Query: 1835  YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESN 1892
             Y+FR+ A N  G   P    D I +     PP    +  V E         ++     S 
Sbjct: 16159 YRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSG 16218

Query: 1893  GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
               +P   +  +   +  ++  +  ++  ++    I++   + + I+ ++A+N  G     
Sbjct: 16219 KPAPEIIWNRDDAELPKEAAVETTSISSAL---VIKSCLRQHQGIYTLTAKNAGG----- 16270

Query: 1953  ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
             E +   + +   VP P   P     + ++    +W +PE DGG+ +  Y I  R+  +  
Sbjct: 16271 ERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIEKREADRRG 16330

Query: 2013  WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEE 2072
             W  V    V      ++ L +   Y  RI A N IG+    E+  P  V+  +     E 
Sbjct: 16331 WTSV-TYTVTRHNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAP--VVIKDPLSVPER 16387

Query: 2073  PGEQTEVXXXXXXXXXXXXXWLR-EHNMDADIRSYARGSLLRRDEYFFRI 2121
             P E  EV             W   +++  +DI SY     L   + F RI
Sbjct: 16388 P-EDVEV--TAITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRI 16434



 Score =  220 bits (537), Expect = 4e-55
 Identities = 213/847 (25%), Positives = 345/847 (40%), Gaps = 54/847 (6%)

Query: 1247  DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK------IVDYEREYRIK 1300
             DV++ T II    E  + E+    ++    ++  V       K       +D        
Sbjct: 15843 DVEETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGA 15902

Query: 1301  RGSDVTLLVDYQAFPQPNDEWIV------NSKI-IKKCKHTKPSIDSKSASLTIKKVENT 1353
              G DV ++   Q  P P+  W        + K+ ++  KH    +  +  SL I++ +  
Sbjct: 15903 EGFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKRD 15962

Query: 1354  DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
             D+ +Y L   N+ G A   + ++IL +P  P  P  I E+ +  I + W+ P + G S I
Sbjct: 15963 DSAMYTLTATNSLGTATKSIKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGGSKI 16022

Query: 1413  IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDA--SETTE 1469
               YVVE +E +   W+ V +  K  Q  +Q L     Y FR  A N+  +     SE  +
Sbjct: 16023 TNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPPLYSEPEK 16082

Query: 1470  YYKVIKETKIQSPTVEKPLKN-ITTE--PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
                +       +P V    K+ +  E  P  +   + I G   + K     + +K+K  K
Sbjct: 16083 ARNLFTPPGPPTPKVTDCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWEKVKD-K 16141

Query: 1527  ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKHK 1585
                  +                + +     GE  E + V+ ++ + +    + D   K K
Sbjct: 16142 EIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEK 16201

Query: 1586  V----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
             +    G    + A + G P PE+IW  N +  E  KE  + T   +S + IK   R H  
Sbjct: 16202 IVVHAGGVIRILAYVSGKPAPEIIW--NRDDAELPKEAAVETTSISSALVIKSCLRQHQG 16259

Query: 1642  KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
              YT+ A N  G     V ++V D P     P     ++ +S  + W  P DDGG  +T Y
Sbjct: 16260 IYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNY 16319

Query: 1702  AIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759
              IEK E D   W  V   V R      +Q L +   Y FR+ A+N +G     E + P+V
Sbjct: 16320 IIEKREADRRGWTSVTYTVTR--HNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVV 16377

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXX 1818
             IK  L VP           I N+S+ + W   + +GGS I  Y +E++  G+  +     
Sbjct: 16378 IKDPLSVPE-RPEDVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRIAK 16436

Query: 1819  XXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF--- 1872
                   R      L   ++Y+FR+ A N+IG   P  S   +T  K   PP+    F   
Sbjct: 16437 EDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFEPPNLDLEFRDK 16496

Query: 1873  -VVSESTSRSVTLKWT-EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
              VV    +  +  ++T +PE     P   +    + ++      + T    +    IE  
Sbjct: 16497 LVVRVGETCIIQSRYTGKPE-----PTIKWFKNDEELQANEEIALTTAKNRL-SLTIEKA 16550

Query: 1931  KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
             K      + +  EN++G       + +        P PP  P+    +  N ++ SW  P
Sbjct: 16551 KRDHSGKYMVVLENSIGT-----RKGICTVNVVDRPQPPEGPVIFDEIYRNYMVISWNPP 16605

Query: 1991  EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
               DGGA +  Y +  RD  + +WM V +    T    +  L E   Y+IRI A+N  G+S
Sbjct: 16606 LDDGGAAISNYIVEKRDTNRDLWMPVTESCTRT-SCKVPKLIEGREYIIRICAQNIHGIS 16664

Query: 2051  EPLESDE 2057
             +PL S E
Sbjct: 16665 DPLLSAE 16671



 Score =  215 bits (526), Expect = 8e-54
 Identities = 246/1060 (23%), Positives = 413/1060 (38%), Gaps = 72/1060 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F K P      +G D  L C L      +I W    +++          E      C
Sbjct: 6560 PPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEG-----C 6614

Query: 693  SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S  L I  ++    G Y   A N  G       +K++    EPP  ++ L +     GE 
Sbjct: 6615 SATLHILGLEASDAGEYECKATNNVGSDLCQGSVKLR----EPPAFVKKLSNTTAISGEE 6670

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI------LKPKKVKDE--GVY 803
            V+L   V G+   T++W ++   +       DG+   IT       LK  K      G Y
Sbjct: 6671 VVLLTTVKGSQPMTVSWVQDKDHILR-----DGENRKITFENNEVTLKVFKADSTTAGKY 6725

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            T + +N  G+AE +A +TV        EP   +++   I+V       L   V+  P   
Sbjct: 6726 TCQLKNDAGVAECTANLTV-------LEPAAIVDKTDSISVTAGEAAALECTVSGTPELK 6778

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              W+++   +S  +     F      L + + +   D+G+Y     N  G  S   ++T+
Sbjct: 6779 PKWFKDGVELSSGKKYKITFSKMISSLKLLSTERS-DTGEYTFSIKNEVGSDSCAMQLTV 6837

Query: 924  DVEKVTFVKHLQKSYETEE--GKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEG 979
             ++K+      +K  +T+   GK++ L+C+ S +  ++  W+HN+ EI    + EI    
Sbjct: 6838 -LDKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTE 6896

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035
                         D G  KC   +     ETS  LVVKE  P F+   Q  E        
Sbjct: 6897 NTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEP-PSFVTTPQPVEALPGTTVT 6955

Query: 1036 LEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-ILRD 1093
                +   T   + W R  + I   ++  +   RG    L + N      GEY+C I+ D
Sbjct: 6956 FTATVQGSTPMKLKWFRGSKEIVSGRS-CEIALRGDTAILELHNIDKSHAGEYTCQIIND 7014

Query: 1094 ---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149
               E+C   + V E     + +L+N  V  G     E         LV+W KDG EI  S
Sbjct: 7015 AGKENCPVNLFVKEAA-HFVKKLKNLSVEMGKSLILECTYAGSPKILVKWHKDGQEIYSS 7073

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEF 1205
                +T       L+  + D + AG+Y+CEV N      C A +++ EP   F +   E 
Sbjct: 7074 YKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAGHDICEAAVSILEPP--FFIESLEP 7131

Query: 1206 ILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            + V A     L  +I     + ++W+K    +  +    +        L + K  + D  
Sbjct: 7132 MEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEFFKGIACLKLAKVAKSDIG 7191

Query: 1265 EYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
            EYTC     +  A S+  L V+ V+ PP             G  V               
Sbjct: 7192 EYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVS 7251

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W+ + + ++       S D  SA L I K E   +G Y     N+ G A     +T+ + 
Sbjct: 7252 WLKDGEALRSDSEYTMSFDDNSAVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQEP 7311

Query: 1381 PSPPG-KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-Q 1437
              PP     ++ +D S  +    E   TG+  I + +  ++++I T     +  +  T  
Sbjct: 7312 RYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPH 7371

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
             +I       S R+  +A N  D+   S +TE    +KE KI     +KP   I     +
Sbjct: 7372 LTILKADKADSGRYSCHASN--DVGKDSCSTEVS--VKERKIPPSFTKKPSTTIEDIEGK 7427

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXX-XXXXXXXXXXXYKCIAF 1553
             +++     G     V WY+DG+++ T+     T+++                 Y C A 
Sbjct: 7428 VVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKAT 7487

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            N+ G       V I  + V    +  +K      G+   ++  + G PP ++ W K+  +
Sbjct: 7488 NEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRE 7547

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            L +     IT  + T+ + +  + ++ S  Y  +A+N AG
Sbjct: 7548 LSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKATNEAG 7587



 Score =  215 bits (525), Expect = 1e-53
 Identities = 237/987 (24%), Positives = 404/987 (40%), Gaps = 71/987 (7%)

Query: 1127  EIELTKGDALVRWFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNS- 1183
             E + +  D   RW K        N   +T  ++G++ + ++     + AG +S    +S 
Sbjct: 28608 ERKASSDDEEARWLKCNYTTITENFFTVTSLVEGEQYEFRVIA--RNGAGVHSMPSASSG 28665

Query: 1184  --KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTE 1240
                C    T  +  ++  L + E I + A +D  L   +  +    V W K    ++  E
Sbjct: 28666 LITCKDEYTPPKAELDSKL-VGETISIRAGSDLVLDAAVGGKPEPKVFWAKGDKELDPGE 28724

Query: 1241  KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYR 1298
             K++L     +   II+ C  +D   Y   + +A    T+ + V+V++ P           
Sbjct: 28725 KYSLTYTSTRAMAIIKSCDRNDTGRYILTVKNASGIKTSAVNVKVLDTPGPPAG---TIT 28781

Query: 1299  IKRGSDVTLLVDYQAFPQPNDE----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
             I R +D    V ++   +   +    +IV  +   +        + K+ S    K+   +
Sbjct: 28782 ISRVTDEKCTVSWKIPLEDGGDHVSHYIVERRETSRLNWVIMETECKTLSCVSTKLIKNN 28841

Query: 1355  AGIYKLRLENNCGHA-DVEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGN 1409
               I+++R  N  G    +E    I       P+PPG P+I  I    + I W +PEN G 
Sbjct: 28842 EYIFRVRGVNKYGPGVPLESEPVIARNAYTVPTPPGTPDITAIGKEHVIIEWFKPENDGG 28901

Query: 1410  STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             S I  Y+V+ +E  +  W  V     I  T+  I  L   S Y+FR  AVN    S  S+
Sbjct: 28902 SEIKNYLVDKREKSSVRWTRVNKTYTIYDTRLKITGLLEGSDYQFRVSAVNAAGTSAPSD 28961

Query: 1467  TTEYYKVIKETKIQSP--------TVEKPLKNITTEPNED--IELT-CIFGGVPQPKVTW 1515
              ++Y      T   +P        T +  +    T P  D   ++T  I   + +    W
Sbjct: 28962 ASQYAHCKDPTYTPAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGTEQW 29021

Query: 1516  YRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
             YR  +K L + + T                        F++ G +ET+    + + P I 
Sbjct: 29022 YRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMGTGEFSE-GSMETAPSERV-EIPDIE 29079

Query: 1575  ISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
             + +E  K    + G+   +   + G P P + W K G  L++ + +  TT+  TS+I ++
Sbjct: 29080 LPDELKKTVCIRAGNTLRLNVTVSGRPAPVITWRKTGIDLQS-RGFIDTTENSTSLI-VE 29137

Query: 1634  ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             ++ R  + KYTIEA N +G  ++ + +K+YD P  P G V +++ ++ESV I W  P  D
Sbjct: 29138 KVHRYDAGKYTIEAENPSGKKTITILVKIYDTPG-PCGAVNVKDYTKESVVITWDVPTID 29196

Query: 1694  GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
             GG  +  Y IEK E     + K    +     Y I  L E  +Y FRV+ +N  G  E  
Sbjct: 29197 GGAHINNYIIEKREASMKSY-KTVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPC 29255

Query: 1754  ES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-K 1811
             E+ EP+++     VP               +V + W     +GGS +  + +E  + G  
Sbjct: 29256 ETPEPVLVCEVPSVPQDLYLIDTT----KSTVILGWEKPLHDGGSRLSGFVIEACKTGTD 29311

Query: 1812  KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--- 1866
             +W           +  I  L+ N  Y FRI A N  G S P      +TI +    P   
Sbjct: 29312 RWMNVAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKID 29371

Query: 1867  --SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
                 P+  +V+    + + L    P     +P+ ++      +K K     +       +
Sbjct: 29372 LTGIPQK-IVNVPAGKPIVL--NIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTK 29428

Query: 1925  HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
               +      D   + ++ +N  G +     + + L+K    P  P  P++I  V +  V 
Sbjct: 29429 LTVRETTIDDTGDYTLNVKNVSGTATEV-IRVIILDK----PGVPVGPMKIEEVDATSVT 29483

Query: 1985  TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              SW  P+ DGGA + GY +  RD  +  WM V +  V    F    L E   Y+ R+ A 
Sbjct: 29484 CSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSE-SVTRPVFKFTRLVEGTEYVFRVAAT 29542

Query: 2045  NEIGLSEPLESD----EPFKVIPGEGS 2067
             N  G+   L+S+    +  K +PG  S
Sbjct: 29543 NRFGIGGFLQSEVVECKSVKTVPGAPS 29569



 Score =  215 bits (524), Expect = 1e-53
 Identities = 242/1128 (21%), Positives = 442/1128 (39%), Gaps = 74/1128 (6%)

Query: 595  TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD--ILEGIPPTFSKKPKAQYVDEGSDIL 652
            T  L++   + DH  E T             +   ++  +PP F ++ +   V+ GS   
Sbjct: 4574 TYTLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSAK 4633

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
             EC +   P     W   G E+   E   +      H + S L+I +      G YT  A
Sbjct: 4634 FECEIEEAPGVTFKWFKSGTELRHSEKCRII---SRH-HTSSLEIFSPAVADSGEYTCKA 4689

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             NR G  S     K+   E  PP+ +    SM +  G+       + G+    + W K+N
Sbjct: 4690 SNRHGSDSCS--AKLTVTELFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDN 4747

Query: 773  KPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
              +         SD + + + IL  +   D+G Y  KA NS G A     + V       
Sbjct: 4748 IAISLDDHYKESSDKNRYFLEILNLQH-SDQGTYLCKASNSVGTATCCTELRV------- 4799

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             + P F+  F+  TV     ++L  +V  +   SI W R+ + +  +      F+ E I 
Sbjct: 4800 VDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFE-EKIA 4858

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
             +        D+G Y C A+N AG SS  + VT+  E   FVK L+     ++G +  L 
Sbjct: 4859 CLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQ-EPPVFVKRLEPKILWKQGMSSRLS 4917

Query: 950  C--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---- 1003
            C  + S  +   W+ N K ++  +  +I  +              D G   C V +    
Sbjct: 4918 CTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGC 4977

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNK 1062
            +  S+ + VKE  P F ++L+  EV +   A LE E+      ++ W +D   +     K
Sbjct: 4978 ESCSSQVTVKEP-PAFKKELRLVEVVKGCTAHLECEMTGTAPFEITWFKDKNPVS-SDTK 5035

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVN 1119
            Y+   +     L I+     D G+Y C + ++     T  V  ++ PP  + +++N    
Sbjct: 5036 YNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLKDPPSFVKKVENTTAV 5095

Query: 1120 KGNKATFEIELTKGDA--LVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEY 1176
             G+    +  + KG A   V+WFKD   ++  + +I  T +     L I +  ++  G+Y
Sbjct: 5096 LGSAVKLQGTI-KGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKY 5154

Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYK 1231
            +C    E G  KC A +TV+EP+  F +  P  I V A   A L  ++     L V W+K
Sbjct: 5155 TCQAENEAGKQKCEATVTVQEPA-RF-VEKPPCISVTAGDSATLECKVSGSPDLKVKWFK 5212

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPK 1289
                +    K+ +        L I      D  EY   + +   K      + V+E PP 
Sbjct: 5213 DGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINVLE-PPV 5271

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
                 +   +  G+ V L   +        +W    K +          ++ S+SL +  
Sbjct: 5272 FSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLELHA 5331

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
            ++ + +  Y  ++ N+ G       + + + P       ++++D + + +      N   
Sbjct: 5332 LKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPK-----FVMKLDLTKLVL------NGSL 5380

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-----A 1464
            +T+   V    EI +  W   +    +    Q   T+S    R  +    D  D     +
Sbjct: 5381 ATLECKVAGSPEI-SIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQAS 5439

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
            S+          T  + P   KP ++       D+ L     G    +++ ++D K+++ 
Sbjct: 5440 SDAGSDRCSCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRN 5499

Query: 1525 AK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNE 1578
             +    +  ++                Y+C   N+ G+     +V +++ P  V  + N 
Sbjct: 5500 DRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPSFVQKMDNT 5559

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            ++     V     +  V++G  P  + W K+ ++++  +   I+ + +T+VI I  ++  
Sbjct: 5560 NVLLAKDVS----LQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLK 5615

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            H  KYT  A N AG+      L V +  +  E    +    R+  T+E
Sbjct: 5616 HGGKYTCHAQNEAGSQKCTAVLTVKEPANITEQAKSVSVTVRDPATLE 5663



 Score =  213 bits (520), Expect = 4e-53
 Identities = 264/1195 (22%), Positives = 453/1195 (37%), Gaps = 91/1195 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  +EK   +    GS VQF   + G P   I WF+ T                      
Sbjct: 5832 PSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDT---------------------- 5869

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
             +EV    +G    V KN     SS+ EL    P SD G +               A + 
Sbjct: 5870 -KEV---SSGIDCSVQKNDT---SSSIELFFAKP-SDSG-QYVCEVSNDVGSDSCQATLF 5920

Query: 630  EGIPPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
               PP F++KP K   V     ++ EC++   PE D  W   G +I P +   +     +
Sbjct: 5921 VKEPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSL 5980

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
                + L+I +      G Y   A N  G  S  + L++K    EPP +++PL  + V  
Sbjct: 5981 ----ARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVK----EPPVLVKPLSPLEVVN 6032

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTL 805
            G +      V G     +TW K++K +K+ L         SI  L  +K    D G Y  
Sbjct: 6033 GSNAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQC 6092

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
               N  G   + + ++++EP       P F+ R + +       ++    V  +P  SI 
Sbjct: 6093 IVANEVGSCSSQSTLSIKEP-------PSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQ 6145

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W ++   I    +I + F+  N+  +   V   I SG Y C A N AG+    +  T+ V
Sbjct: 6146 WQKDESWILEDPSIQRTFEN-NVATLTIPVCESIHSGKYTCQAMNEAGQEKCFS--TLVV 6202

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983
            ++   +    +      G  V  EC+ S T  +  KW  + KE+       +        
Sbjct: 6203 QEPPQIIEKPEVINVTAGDPVSFECKVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQ 6262

Query: 984  XXXXXXXXXDVGVIKCIVKDQETS-----TMLVVKETIP-EFIRKLQDFE-VKEKDVAIL 1036
                     D G     V +  ++     T+ V+++ IP  FI+ L + E +  K+V I 
Sbjct: 6263 LKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPPSFIKPLMEMEEIIGKNVQIG 6322

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
                 S    V WE+DG  +  +      +    +  L I      D G Y+C L +++ 
Sbjct: 6323 CKISGSLPITVEWEKDGTKLSGRTKHKILQDENSV-SLDIECLEKADTGTYTCKLANKAG 6381

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156
            + E +      E    + N  V    K +F+         V+WFKD +E+         +
Sbjct: 6382 SCECSGTLRVKESQAVIPNTTVRF--KGSFK---GTPPFTVKWFKDDTELICGPSCFTGL 6436

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
            +G    L ++   +  +G YSC++ N         E P   F  +LP   +V       L
Sbjct: 6437 EGLSCFLDLFAVGISHSGTYSCQISND-------AEPP--EFVQKLPAAKVVKMGEPLQL 6487

Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
              ++     L ++WYK  +++ D     +  D     L I   + DD   YTC   +   
Sbjct: 6488 ECKVTGTAPLRISWYKNDAILSDGGNLRMTFDNSVAVLEISTSSFDDNGVYTCEAQNDAG 6547

Query: 1276 TTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            T      + ++ PP            +G D +L  + +        W  + K +K+ +  
Sbjct: 6548 TKSCSTALTIKEPPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKY 6607

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            K   +  SA+L I  +E +DAG Y+ +  NN G    + +V + + P+   K +     S
Sbjct: 6608 KFVSEGCSATLHILGLEASDAGEYECKATNNVGSDLCQGSVKLREPPAFVKKLSNTTAIS 6667

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
                +     + +   T+ +   +   +   E   +      + +++  K +S+   + Y
Sbjct: 6668 GEEVVLLTTVKGSQPMTVSWVQDKDHILRDGENRKI-TFENNEVTLKVFKADSTTAGK-Y 6725

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
                 + +  +E T    V++   I   T      +I+    E   L C   G P+ K  
Sbjct: 6726 TCQLKNDAGVAECTANLTVLEPAAIVDKT-----DSISVTAGEAAALECTVSGTPELKPK 6780

Query: 1515 WYRDGKKL---KTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            W++DG +L   K  K T+                   Y     N+ G    +  + +  K
Sbjct: 6781 WFKDGVELSSGKKYKITFSKMISSLKLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDK 6840

Query: 1571 PVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             V  + +  +K     VG    +     G  P  + W+ N  ++ +   Y IT  E T  
Sbjct: 6841 IVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTENTCT 6900

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            +++  LK S S  Y  +A N+AG +    +L V + PS    P  +  +   +VT
Sbjct: 6901 LKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPSFVTTPQPVEALPGTTVT 6955



 Score =  211 bits (516), Expect = 1e-52
 Identities = 213/896 (23%), Positives = 354/896 (39%), Gaps = 52/896 (5%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVK 1249
             V+ P I    +L + +++ A     +  EI    + V +W K    IE   +F + S + 
Sbjct: 25419 VDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLT 25478

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
               TLI+R     D  +Y   L +   T  L V       K++D  R        D+T L 
Sbjct: 25479 STTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNC-----KVLD--RPGPSSGPLDITGLT 25531

Query: 1310  DYQAF-----PQPN-----DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
               +       PQ N       +IV  +   +   T    D K+ +  + K+   +  I++
Sbjct: 25532 AEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVYADMKATTCKVTKLLKGNEYIFR 25591

Query: 1360  LRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +R  N  G      +D    +     P+ P    +  + S ++ ICW+ P + G S+I  
Sbjct: 25592 VRGVNKYGTGEALESDPAKAMDPFTVPAAPTDVEVTSVTSEAMTICWERPISDGGSSISG 25651

Query: 1415  YVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             YV+E +E     W+ V  K +   +    NL+    Y +R +A N   +S  S      K
Sbjct: 25652 YVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSAPSVPCPLTK 25711

Query: 1473  VIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPK-VTWYRDGKKLK-TAKATY 1529
                   + SP  + K + +  T            GG P    +  YR+      T     
Sbjct: 25712 AEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEYRNTNDDDWTVGVNN 25771

Query: 1530  ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQK 1583
                               +   + N  G  E S     Q       +PV  ISNE  K  
Sbjct: 25772 TKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDPQVAKEREDEPVFLISNEMRKTL 25831

Query: 1584  H-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
               K G  + +    +G P P V+W K    L      +I T +  + + I++  R  S K
Sbjct: 25832 VVKDGSSFTLRVPFKGKPVPHVMWNKPDVDLR--VRASIDTTDTCTSVTIEQATRDDSGK 25889

Query: 1643  YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
             YT+   N AGT+++ +++KV D P  P   + ++E+++ S TI W  P ++GG  +  Y 
Sbjct: 25890 YTVTLQNVAGTATLTLSVKVLDSPG-PPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYL 25948

Query: 1703  IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
             ++  E     W ++++    + TY +  L E   Y FRV  +N  G    LE++     T
Sbjct: 25949 VDLREATKMGWSRISNSCPRL-TYKVTNLQEGGVYYFRVTGENEYGVGVPLETKE---GT 26004

Query: 1763  ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXX 1821
              +              +  ESV + W   E +GGS I +Y VE  ++G +KW        
Sbjct: 26005 KITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCGSTKS 26064

Query: 1822  XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-QPRNFVVSES-TS 1879
                 +  L  N  Y FR+ A N  G S P      + +   L  P    ++F  + +   
Sbjct: 26065 THFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKDQLEAPEINMKDFQHNTAYVK 26124

Query: 1880  RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
                 LK   P +    P  +   + + +K            S+  +  E++   D   + 
Sbjct: 26125 AGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESV-ASDAGRYD 26183

Query: 1940  ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
             I+A N+ G +  +    V L++    P P   P+E+  +  + V   W  P +DGG+P+ 
Sbjct: 26184 ITASNSNGTT-KSFVNVVVLDR----PGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPIT 26238

Query: 2000  GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              Y +  R+ T   W+EV    V      I  L+    Y  RI A N  G+SE ++S
Sbjct: 26239 NYIVLKRETTTANWIEVSSA-VARCTIKIMKLNTGVEYQFRIKAENRFGISEHIDS 26293



 Score =  211 bits (515), Expect = 2e-52
 Identities = 174/697 (24%), Positives = 296/697 (42%), Gaps = 34/697 (4%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438
             P+PP  P I +    SI++ W  P   G S +  Y+VE  E  T +W     K +T TQ 
Sbjct: 28975 PAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGTEQWYRATQKTLTSTQY 29034

Query: 1439  SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEP 1495
             ++  L +N  Y FR  AVN +   + SE +   +     +++ P +E P    K +    
Sbjct: 29035 TVTGLASNKKYSFRVAAVNAMGTGEFSEGS--METAPSERVEIPDIELPDELKKTVCIRA 29092

Query: 1496  NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAF 1553
                + L     G P P +TW + G  L++     T EN                Y   A 
Sbjct: 29093 GNTLRLNVTVSGRPAPVITWRKTGIDLQSRGFIDTTENSTSLIVEKVHRYDAGKYTIEAE 29152

Query: 1554  NDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             N  G+   + +V I   P      N     K  V   W V  +  G      I  K    
Sbjct: 29153 NPSGKKTITILVKIYDTPGPCGAVNVKDYTKESVVITWDVPTIDGGAHINNYIIEKREAS 29212

Query: 1613  LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKP 1669
             +++ K   +TT+ K ++ RI  L+      + +   N  G      T   + V + PS P
Sbjct: 29213 MKSYK--TVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPCETPEPVLVCEVPSVP 29270

Query: 1670  EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
             +   ++ + ++ +V + W+ PL DGG  L+ + IE  +   +RW+ VA V   V  + I 
Sbjct: 29271 QDLYLI-DTTKSTVILGWEKPLHDGGSRLSGFVIEACKTGTDRWMNVAHVKSSVLQHTIV 29329

Query: 1730  KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYIT 1787
              L EN +Y+FR+ A+N  G SE  +   P+ I+   ++P           ++      I 
Sbjct: 29330 SLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKIDLTGIPQKIVNVPAGKPIV 29389

Query: 1788  WFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
                  K   +P+  +    V++K +  + K           +++ +I+ T  + +  +N 
Sbjct: 29390 LNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETTIDDTGDYTLNVKNV 29449

Query: 1845  IGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
              GT+   T   ++ I   L  P  P     + E  + SVT  W  P+ +GG+ ++ YI+E
Sbjct: 29450 SGTA---TEVIRVII---LDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVE 29503

Query: 1904  FKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
              +      W   ++V  SV     +   + E  E +FR++A N  G+    +S+ V  + 
Sbjct: 29504 QRDAHRPGW---MSVSESVTRPVFKFTRLVEGTEYVFRVAATNRFGIGGFLQSEVVECKS 29560

Query: 1962  HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
               TVP  P+ P EI  V  + +  +W  PE +GG+ + GY I  ++     W+ + K  V
Sbjct: 29561 VKTVPGAPSTP-EILDVSHDGMTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPV 29619

Query: 2022  NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                ++    L E   Y  R+ A N  G  +P  + +P
Sbjct: 29620 TMTRYRATGLIEGLEYEYRVTAINSRGTGKPSANSKP 29656



 Score =  210 bits (512), Expect = 4e-52
 Identities = 175/676 (25%), Positives = 306/676 (45%), Gaps = 39/676 (5%)

Query: 632  IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            IPP+F+KKP     D EG  + +E R+       + W   G EI   +   V  +S + +
Sbjct: 7409 IPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAV 7468

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
             C    I   +    GTY   A N  G AS  + + I T +K PP    PLK + V +GE
Sbjct: 7469 LC----IKKSQLSDSGTYVCKATNEAGTASFEVSVHI-TAQKVPPSFDLPLKPVTVNEGE 7523

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808
            ++ LS  V G+P   I W K+ + + +              L+  +V   D G Y  KA 
Sbjct: 7524 TLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKAT 7583

Query: 809  NSEGI---AETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            N  G    A   A      P E +  +   FI   + + + EKGT   +A+V  +P+P++
Sbjct: 7584 NEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIPNV 7643

Query: 865  TWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             W +     ++    I+    G+  ++ I  V ++ DSG Y+CVASN  G+      + +
Sbjct: 7644 KWMKGKWRQMTHGGRISIEQKGQEAKMEIKEV-TKSDSGQYRCVASNKHGEIECSTDLNV 7702

Query: 924  DVEKVTFVKHLQ------KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-DHREII 976
            D +K T V+ ++      K    +E K + +  +    V  K Y     + G+ D R ++
Sbjct: 7703 DEKKETTVEMVKLKKTPSKQKSPKEEKDIDI-VELLRNVDPKEYEKYARMYGITDFRGLL 7761

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV-----VKETIPEFI-RKLQD--FEV 1028
            Q                 G I     +++ + ++      +++T P  + R + D    V
Sbjct: 7762 QAIEFLKKEKELESGRPEGEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTV 7821

Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            K++ V   E++IN     + W +  + +    +KYD +  G    L I++    DEG Y 
Sbjct: 7822 KKEAVFECEIKINYPEITLSWYKGTQKLD-SGDKYDIKIVGDRHILKIKDCQTRDEGNYR 7880

Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
             +      +A++TV+E   E+   +Q+    +G   T   +L+  +   +WF++G  ++ 
Sbjct: 7881 IVCGPHISSAKLTVLEA--EVEKPMQDVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEP 7938

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             +     +    QKL I D   +D GEY+C+  N + TA L +E   I+FT R+ + I+V
Sbjct: 7939 HSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRI-QNIVV 7997

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
              +  A    E+  +   VTWYK    ++++ K+T  S+ ++  +IIR  +  D+  Y+ 
Sbjct: 7998 REHQSATFECEVSFDNAVVTWYKDTWELKESPKYTFRSEGRRHFMIIRNVSSADEGVYSV 8057

Query: 1269 VLL-----DAKSTTKL 1279
            ++      +AKST +L
Sbjct: 8058 IVRLEPRGEAKSTAEL 8073



 Score =  210 bits (512), Expect = 4e-52
 Identities = 219/907 (24%), Positives = 378/907 (41%), Gaps = 66/907 (7%)

Query: 1188  ILTVEEPSI-NFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLI 1245
             I+T +E  I        + + + A  +  L+  I    +  VTWYK    + D     + 
Sbjct: 27582 IMTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEV-DKMLVDIT 27640

Query: 1246  SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSD 1304
             + +   +L IR    + +  YT    ++  TTK+ V V V+  P   +    +       
Sbjct: 27641 TVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQDTPGPPEGPLRFTNISAEK 27700

Query: 1305  VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYKLR 1361
              TL   + + P+ +    +++ +I+K + ++ S   + SK  + +    +      Y+ R
Sbjct: 27701 ATL---WWSPPENDGCAAISNYVIEKRETSRISWALVTSKCEACSFNATKLIKGNEYQFR 27757

Query: 1362  LE--NNCGHAD-VEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +   N  G    +E +  I       P  PG P+   +  +SI +CW  P + G + I  
Sbjct: 27758 VSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTPDCTHVTGNSITLCWTRPRHDGGNEIKQ 27817

Query: 1415  YVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
             Y++E +E  +  W+ V   + IT+ +  + NL   + Y FR  A N   I  AS  +  +
Sbjct: 27818 YILERREKKSLRWVKVSAKRPITELRHRVTNLTEGNEYEFRVMAENGAGIGPASGISRLF 27877

Query: 1472  KVIKETKIQS-PTVEKPLKN----IT---TEPNEDIELTCIFGGVPQPKVT---WYRDGK 1520
             K  + T   S PT+ K + +    +T   T+P  D  L  I   +   K +   W+R   
Sbjct: 27878 KCREPTSAPSAPTLVKVIDSTKTSVTLAWTKPVFDGGLEIIGYIIEMCKASLEEWHRVNN 27937

Query: 1521  KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVIT 1574
             +  T   T+                  ++  A N  G+ E S    I Q       P I 
Sbjct: 27938 Q--TCIQTHYR-----VTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEID 27990

Query: 1575  ISNEDIKQKHKVGDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
             I + D KQ H V +   V   I   G P P   W K    L      +I T +  S + I
Sbjct: 27991 I-DADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDL--GVMVDINTTDTFSTLTI 28047

Query: 1633  KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             +   R  + KYT+   N +G  ++ +T+KV D P  P GP+  ++++R ++T+ W  P +
Sbjct: 28048 ENCTRYDAGKYTLSLENNSGRKTITLTVKVLDTPGPP-GPLSFKDVTRGALTLMWDAPSN 28106

Query: 1693  DGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             DGG  +  Y +EK E     W +V++   R +    +  L+    Y FRV A+N  G  E
Sbjct: 28107 DGGARVHHYIVEKREASRLSWQEVSERCTRQI--LRVINLDIGVAYFFRVTAENQYGKGE 28164

Query: 1752  ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
               E +EPI+   A + P+            + +  + W   E +GGS I  Y VE +++G
Sbjct: 28165 PYEMTEPII---ATEEPASPKRLDVIDT-TSTTASLVWMKPEHDGGSRITGYIVETRKKG 28220

Query: 1811  K-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
                W            ++ L  NT Y+FR+ A+N+ G S P  +   + I +    P+  
Sbjct: 28221 SANWVFGGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTAD 28280

Query: 1870  RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIE 1928
              + +  +  +      +       G P      + + +K K   ++ + +        ++
Sbjct: 28281 LSSIDKQLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVK 28340

Query: 1929  NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988
             + K  D   + ++ EN  G    T +  V        P+PPT P+EI  V S   + +WG
Sbjct: 28341 DAKRGDSGKYYLTLENAAGSKTFTVTVIV-----IGRPTPPTGPVEISGVSSESCVLTWG 28395

Query: 1989  TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              P  DGG  +  Y +  R+   T W  V    V      +  L++   Y  R+ A N+ G
Sbjct: 28396 EPSDDGGTDITNYIVEKRESGSTTWQVVNS-SVKRTTIKVTHLTKYMEYTFRVSAENKFG 28454

Query: 2049  LSEPLES 2055
             +S+ +ES
Sbjct: 28455 VSKSIES 28461



 Score =  209 bits (511), Expect = 6e-52
 Identities = 130/439 (29%), Positives = 207/439 (47%), Gaps = 15/439 (3%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTSSV-----EVTLK-VYDKPSKPEGPVIMREISRESVT 1684
             R+K L      K+ + A N AG         ++ +K   D P  P  P + +++++ S  
Sbjct: 13658 RVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPIDPPWAPGKPTV-KDVAKTSAF 13716

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
             ++W  P  DGG ++  Y +E  +   + W++VAD    +E + ++ L E  EY FRV A 
Sbjct: 13717 LQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSLEHF-LKGLMEKQEYSFRVRAV 13775

Query: 1745  NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
             N  G SE  E S+P++ K  L+ PS            N S  + W   E++GGSPI +Y 
Sbjct: 13776 NVAGESEPSEPSDPVLCKERLNPPSPPRWLLVVSSSRN-SAELKWTAPERDGGSPITNYI 13834

Query: 1804  VEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             VE +   +K W+            +  L+  + Y FR+ A N +G S     +D +    
Sbjct: 13835 VEKRDVRRKGWQAVDTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSVLAKD 13894

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
             T   P  P N  ++E +   V LKW  P+++GG P+  Y+IE K   G  W K     G 
Sbjct: 13895 TFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKSGKTSGP 13954

Query: 1922  VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
                + + ++ E  E+ F++SAEN  GV  P+E   + + +  T P  P   L I     +
Sbjct: 13955 DCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIEDPTGPPSPPQELHITEAARD 14014

Query: 1982  IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD---LSENHTYM 2038
              +  +W  PE +GG+P++GY+I + +     WM V    V  LK+   D   +     Y 
Sbjct: 14015 HICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNSRPVKELKYRAGDEEGIVPEKEYT 14074

Query: 2039  IRIYARNEIGLSEPLESDE 2057
              R+ A N +G SEP +  E
Sbjct: 14075 FRVRAVNSVGASEPSDISE 14093



 Score =  209 bits (511), Expect = 6e-52
 Identities = 171/704 (24%), Positives = 289/704 (41%), Gaps = 38/704 (5%)

Query: 1373  MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
             M   I   P PP  P I +   ++    W  P   G   +  Y+VE+++    +W+    
Sbjct: 20301 MTKDIAYPPGPPSNPRITDTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTT 20360

Query: 1433  ITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-K 1489
             I    T+  + NL++   Y FR  A+N   + + SE  +  +++   ++    ++  L K
Sbjct: 20361 IPLRITEFVVSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRK 20420

Query: 1490  NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX 1547
              +  +    I +     G P P+V WY++   LK      T E+                
Sbjct: 20421 TLVVKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGK 20480

Query: 1548  YKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
             Y     N  G+      V +   P   + +   +I  KH +  +W +  +  G      I
Sbjct: 20481 YVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREIT-KHSITLQWEIPLIDGGSKIKNYI 20539

Query: 1606  WYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LK 1661
               K   +    K Y+ ITT  +    +I +L+ +    + + A N  G      T   ++
Sbjct: 20540 IEK---REATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIR 20596

Query: 1662  VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
                 PS P+  +I+ ++S+++ T+ W  P  DGG  +T Y IE    D+++W  V  +  
Sbjct: 20597 ASQAPSAPDD-LIVTDVSKDTATLAWTKPKHDGGSRITGYVIEAQLKDSDQWAHVTTIK- 20654

Query: 1722  DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI-- 1779
                 Y   +L EN EY+FR+ A N  G SE  ES P+VIK     P           +  
Sbjct: 20655 -ALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVA 20713

Query: 1780  ---DNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTT 1834
                DN  V I      +    P++ +K E ++  + ++             I ++     
Sbjct: 20714 KAGDNLKVEIPVLGRPR----PLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDG 20769

Query: 1835  YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
              Q+ +  +N +GT    T +  + +     PP+ P    + E +   V + W  PE++GG
Sbjct: 20770 GQYSMTGKNILGT---VTENITVQVHDIPGPPTGP--IKLDEVSCDYVLISWEAPENDGG 20824

Query: 1895  SPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
              PI NYI+E +   G SW ++  TV  +  +     +    E  FR+ A+N  GV     
Sbjct: 20825 VPINNYIVEMRETTGTSWMELAATVIRTTFKAA--RLTTGIEYQFRVKAQNRYGVGPYIT 20882

Query: 1954  SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
             S  V       VP  P  P +I     + +  SW  P  DGG+P+LGY+I  ++    +W
Sbjct: 20883 SGPVVAAYPFDVPGQPGIP-QIVAFTKDAMTISWNEPSSDGGSPILGYHIERKEKNSILW 20941

Query: 2014  MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
               + K  V    F    L +   Y  R+ A N  GLS+  +  E
Sbjct: 20942 QRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSE 20985



 Score =  209 bits (511), Expect = 6e-52
 Identities = 200/800 (25%), Positives = 337/800 (42%), Gaps = 52/800 (6%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVK 1249
             +E P IN          V A ++  + + +  + L  V+  K   V++ T +F       
Sbjct: 26106 LEAPEINMKDFQHNTAYVKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTD 26165

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
                + +R+    D   Y     ++  TTK  + V V++ P   V       I   S    
Sbjct: 26166 SLIIYLRESVASDAGRYDITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDS---- 26221

Query: 1308  LVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIK-KVENTDAGI---YKLR 1361
              V  +  P   D    I N  ++K+   T   I+  SA      K+   + G+   ++++
Sbjct: 26222 -VSLKWLPPAYDGGSPITNYIVLKRETTTANWIEVSSAVARCTIKIMKLNTGVEYQFRIK 26280

Query: 1362  LENNCG---HADVEMNVTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
              EN  G   H D +     L    P  P +P +  +   SI + W EP + G S +  Y 
Sbjct: 26281 AENRFGISEHIDSQTVTVSLPYTLPVAPSQPWVSAVTKESIVVNWKEPSSDGGSHVFGYH 26340

Query: 1417  VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
             ++ ++ ++  W  V    I  T   + N+     Y F+  A N   I   S++++   V+
Sbjct: 26341 LQMKDRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSD--PVL 26398

Query: 1475  KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYE 1530
                  + P   +         +   +     GG    K+T Y    +DG K + +KA   
Sbjct: 26399 AIDACEPPNSVRVTDITKNSISLAWQKPSYDGG---SKITGYLIEMKDGPKGRWSKANLT 26455

Query: 1531  NRXXXXXXXXXXXXXXXY--KCIAFNDHGEVET-SCVVG------IQQKPVITISNEDIK 1581
             N                Y  + +A N  G V   S +VG          P + +  E + 
Sbjct: 26456 NVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLD 26515

Query: 1582  Q-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
               K+K G    +   I   P P + WYK+G +LE+  + +I+   + + I ++E  R ++
Sbjct: 26516 VVKYKAGATVQLKIGIVAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNT 26575

Query: 1641  SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
               Y ++  N+ G++   V + V DKP  P G +  ++I+ +++TI W PP D+GG  +T 
Sbjct: 26576 GTYELKIKNSLGSAYAAVRVLVQDKPGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635

Query: 1701  YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760
             Y +EK E     W  +++  +D     + +L +  EY+FRV   N  G  + LES P++ 
Sbjct: 26636 YIVEKRETSRIMWSIISEKLQDC-IVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRPVIA 26694

Query: 1761  KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KWKXXXX 1818
             + +   PS          I   ++ + W     +GGS I  Y +E K+E K  +W     
Sbjct: 26695 QNSFVHPS-QPSKPQVTMITRSTMTVVWERPSLDGGSDIDGYYLE-KREKKSLQWFKVIK 26752

Query: 1819  XXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI--TIGKTLTPPSQPRNFVV 1874
                   R  +  L+    YQ+R+ A N+ G   PY SD  I       + PPS+P    V
Sbjct: 26753 DPIRDTRQKVHNLTEGNEYQYRVCAINKAGAG-PY-SDVSIFYKAYDPIDPPSEPTKLRV 26810

Query: 1875  SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEK 1933
              +ST  S+TL W +P  +GGS IT+Y+IE +      W  I + G     E  + ++K  
Sbjct: 26811 VDSTKTSITLGWVKPVYDGGSEITSYVIEQRIADETEWVTISSKGEVRTTEFVVSHLKPG 26870

Query: 1934  DEIIFRISAENTVGVSLPTE 1953
                 +R+SA N VG     E
Sbjct: 26871 VYYYYRVSAVNCVGTGRSIE 26890



 Score =  209 bits (511), Expect = 6e-52
 Identities = 172/622 (27%), Positives = 278/622 (44%), Gaps = 34/622 (5%)

Query: 1379  DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT- 1436
             DKP  PG+ +I+ I   SI I W  PE+ G   I+ Y +E+++   + W    K  +K  
Sbjct: 30062 DKPGQPGEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDR 30121

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             Q +I  L   + Y FR +A NE  +S    T    K  K +  ++P +++ +K+ TT+  
Sbjct: 30122 QFTIGGLMEATEYEFRVFAENETGLSRPRRTAMGIKT-KLSVGEAPCLKEDIKDTTTKLG 30180

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIA 1552
             E   LTC   G P P++ WYR GK+L   +  K + + R                Y C A
Sbjct: 30181 ESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRA 30240

Query: 1553  FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG--DEWLVTAVIEGIPPPEVIWYKNG 1610
              N+ GE+ETS  + +Q  P        +K+K+  G      +  V  G P P+++W+   
Sbjct: 30241 VNEAGEIETSGKLLLQAAPQFH-PGFPLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGK 30299

Query: 1611  NKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
               L   +   I   E  + + I+ ++R +++ +Y ++ SN  GT    + +++ DKP  P
Sbjct: 30300 KPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLP 30359

Query: 1670  EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE-PDNNRWIKVADVDRDVETYCI 1728
             EGPV++  + + SV I WKPP DDGG  +T Y +EK E  +  +W  V+       T  +
Sbjct: 30360 EGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGT-TCRV 30418

Query: 1729  QKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
               L E+  Y FRV AQN  G SE+LE    ++IK+  + P           +  +S  ++
Sbjct: 30419 PNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPG-VPQRPFVSSVTKDSCVVS 30477

Query: 1788  WFPSEKNGGSPIIDYKVEIKQEGK--KW--KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
             W P   +GG+ I +Y +E K+E K  KW               + L     Y+FR+   N
Sbjct: 30478 WKPPTSDGGAKIKNYFLE-KREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCEN 30536

Query: 1844  EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK----WTEPESNGGSPITN 1899
              IG    ++   +  I K+ T    P  F   E     V  K    +         P+  
Sbjct: 30537 -IGGESDWSEISEPVIPKSDTALRAP--FFKDELRDMCVKYKANATFVTKVVGHPKPVVK 30593

Query: 1900  YIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             +    K +    +  K+    G   +  I N  E D   ++I A N +G      S S  
Sbjct: 30594 WYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLG------SISTS 30647

Query: 1959  LEKHATVPSPPTAPLEIRMVGS 1980
             +     VP+    PL ++ +G+
Sbjct: 30648 MNLDVEVPAKIYLPLHLQGMGA 30669



 Score =  206 bits (503), Expect = 5e-51
 Identities = 233/1055 (22%), Positives = 426/1055 (40%), Gaps = 78/1055 (7%)

Query: 660   IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             I E DI   W  +G+ +       +  E +       L + NV+  Q G  +  A+N   
Sbjct: 11119 ISEDDIPGEWKLRGQVLTRSPTCDIRAEGNKRF----LTLKNVQLDQAGEVSYQALNAVT 11174

Query: 718   EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
              A    +L +K  E +      PL+ + V + +       +  +  P + W + +  V +
Sbjct: 11175 SA----MLTVKEIEMD---FTVPLRDVTVHEKKQAKFECTITKDV-PKVLWLRGSDIVTS 11226

Query: 778   ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPP 833
                     DG  H + ++   + +DEG YT+     E + +TS A +TVE    +     
Sbjct: 11227 DQKYDIIDDGKKHML-VINHCEFEDEGEYTI-----EVLGKTSTAKLTVEGMRLK----- 11275

Query: 834   LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
              F++   + TVKE  T +    ++ + VP +TWY+N   + PS T+  + DG+   L I 
Sbjct: 11276 -FVSPISDQTVKEGKTARFELELSHDSVP-VTWYKNETKLHPSRTVLTHVDGKKHILEIK 11333

Query: 894   NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953
             +V       D  C     A   S  A +T+      F   LQ  Y   E   VIL+C+ S
Sbjct: 11334 DVTL-----DDTCQIKAEAKGMSTTANLTVLEGDACFTVKLQ-DYTAVEKDEVILDCELS 11387

Query: 954   HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
               V  KW+HN+ EI       I  EG+            D G+  C     +TS+ L ++
Sbjct: 11388 KDVPVKWFHNETEIKASKMVAIKVEGKRRILNIKKVEDKDKGLYVCDCGTDKTSSTLNIE 11447

Query: 1014  ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
                 + +R +   E+ + + A  EVEI+ +     W+  GE++ P  +  +  + G    
Sbjct: 11448 ARDIKVVRPMYGVELFDGETARFEVEISEDDVHGQWKLQGEVLSPSPD-VEIIEDGAKHT 11506

Query: 1074  LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133
             L + N  V   GE S    +  C+A + V ELP   +T L +  V + ++A FE E+++ 
Sbjct: 11507 LTLYNCKVSQSGEVSFQGANAKCSANLKVKELPISFVTPLADVHVYEKDEARFECEISRQ 11566

Query: 1134  DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
                 RW K   EI+  +  +L  +GK+  L +     +D  +Y  E  +++ +A L ++ 
Sbjct: 11567 AKSFRWLKGSQEIKTDDKFELLQEGKRHILVVKAAAYEDEAKYMFEAEDNRTSAKLVIQG 11626

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
               + F   + + + V     A  ++E+  E + VTWYK    +  ++   +  D K  TL
Sbjct: 11627 IRLEFVRPIKD-VTVKERETAEFSIELSHEKVQVTWYKNDVRLHPSKVVHMSEDGKIHTL 11685

Query: 1254  IIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
               ++ + DD    + + ++A   T +  + V+E  P      ++Y      +V L+ +  
Sbjct: 11686 SFKEVSIDDT---SLIKVEALGKTCEAMLTVLEGEPYFTTKLQDYTAVEKDEVVLMCEVS 11742

Query: 1313  AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
                    +W  +   I   K+     D K   LT+KK E  + G Y     ++   A + 
Sbjct: 11743 K-SSAQVKWFKDGNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLN 11801

Query: 1373  MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEWIS 1429
             +    +    P     + E +++       E +  G+  +    +    +       + S
Sbjct: 11802 IEERDIKIVRPLYSVEVTETETARFETEISEEDVHGHWKLKGDALHQSPVISFTPKHYFS 11861

Query: 1430  VKNITKTQTSIQNLK-TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
             +  +   +   +  K     Y  R      VD S A+  ++    +K   I    + +PL
Sbjct: 11862 ITMMKDCEIKEEGTKHMLILYNVRMDMAGAVDFSAANAKSKAQLRVKARVI---GLLRPL 11918

Query: 1489  KNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546
             K++T    E     C   + G+P   V W+  G KL       E                
Sbjct: 11919 KDVTVTAGETATFDCELSYEGIP---VEWFLGGTKL-------EPSDRVVTRAEGRSHTL 11968

Query: 1547  XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL---VTAVIE---GIP 1600
               + +   + GEV+ +    + Q  +I ++   ++    + D+ +    TA +E      
Sbjct: 11969 TLRDVKLTEAGEVKLTAKDFLTQAQLI-VNEPPVEFTKPLEDQTVEEEATAELECEVSKE 12027

Query: 1601  PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN--TAGTSSVEV 1658
               EV W+++G ++   K+Y++        + I +     S  YT +A +  T+   +VE 
Sbjct: 12028 KAEVRWFRDGQEIRKTKKYDMVADGCKRKLVIHDCTLDDSKTYTCDAKHFKTSAFLNVEP 12087

Query: 1659  TLKVYDKP------SKPEGPVIMREISRESVTIEW 1687
                 + KP       + E      E+SRES  + W
Sbjct: 12088 PYVEFTKPLHDVEVKEKESARFECEVSRESAKVRW 12122



 Score =  206 bits (502), Expect = 7e-51
 Identities = 227/940 (24%), Positives = 390/940 (41%), Gaps = 81/940 (8%)

Query: 1161  QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
             Q+ K+  C L+  G             +  ++ P I     L + I+V A     + +  
Sbjct: 23624 QEYKVRICALNKLGVGEPVPIQGSVKPVDKMDAPEIELDSELRKGIVVHAGGSMRINIPF 23683

Query: 1221  PDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK- 1278
                 + ++ W K    + D  +     D    T+ I  C  +D  +YT  L ++  T   
Sbjct: 23684 KGRPIPEINWTKDDGDLPDKAQIDKGPDFTHLTINI--CDRNDAGKYTLTLQNSAGTKSA 23741

Query: 1279  -LKVEVVEFP--PK---IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
              + V+V++ P  P+   + D  R Y       VTL+ +    P  +    + + II K +
Sbjct: 23742 FVSVKVLDTPGAPQNLFVKDITRNY-------VTLVWEP---PLIDGGSKIKNYIIDKRE 23791

Query: 1333  HTKP---SIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDKPSPP 1384
              T+    +I +K +  + +  + T+ GIY  R+  EN  G     + E +V   D P   
Sbjct: 23792 STRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSV 23851

Query: 1385  GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNL 1443
             GK  + ++  ++ ++ WD+P++ G S I+ Y +E Q   + EWI V  + KT + ++  L
Sbjct: 23852 GKVTLTDVTKTTASLSWDKPDHDGGSRILGYYIEMQPKGSEEWI-VATVCKTCEGTVAGL 23910

Query: 1444  KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
              +   Y  R  A NE   SD         + K+  I+ P+ +      + +  ED+++  
Sbjct: 23911 SSGQEYLLRVLAYNEKGKSDPRPLASPV-IAKDVTIE-PSFKLTFNTYSVQSGEDLKVEI 23968

Query: 1504  IFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXX---XXXXXXXXXXXYKCIAFNDHGEV 1559
              F G P PK+ W +DG+ LK T +    +                   Y   A N+ G V
Sbjct: 23969 PFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATNNIGTV 24028

Query: 1560  ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN---D 1616
                  + I  KP        I       DE   T V+    PP    Y  G ++ N   +
Sbjct: 24029 TEEVAIIILDKPGPPTGPVKI-------DEVSATYVVISWEPPV---YTGGCQINNYVVE 24078

Query: 1617  KEYNITTKEKT-------SVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV----YD 1664
             K    TT  +T       + I+I +LK     ++ + A N  G S S++ T  V    + 
Sbjct: 24079 KRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFT 24138

Query: 1665  KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             +P+ P  P +   ++++ +TIEWKPP ++GG  +  Y +E+ E ++  W K+  +     
Sbjct: 24139 EPAAPGAPFV-SSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDT 24197

Query: 1725  TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
                   L E  EY +RV A+N  G S + + SE +V +   D P           I    
Sbjct: 24198 RLRTNGLEEGIEYEYRVFAENIAGISPSSKVSESVVARDPCDPPG----TPEAIVITRNL 24253

Query: 1784  VYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIY 1840
             + + W   + +GGS I  Y +E K+  +G+  K            I  L     Y+FR+ 
Sbjct: 24254 ITLQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQFTITGLHEEQRYEFRVI 24313

Query: 1841  ARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             ARN  G  S+P  S   IT    +  PS   +    +         ++      G P+ +
Sbjct: 24314 ARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPD 24373

Query: 1900  YIIEFKTVKG-KSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
              I+  K  K   S T  + +  ++      +++    D   F +S  N  G    T+   
Sbjct: 24374 -IVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGG----TKQVP 24428

Query: 1957  VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
             + + K    P PP  PL++  V +      W  P  DGGA +  Y I  R+ ++  W  V
Sbjct: 24429 INV-KVLDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSWTVV 24487

Query: 2017  GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
              +  +  + + +  L   + Y+ R+ A N+ G+ EPLES+
Sbjct: 24488 -EPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESE 24526



 Score =  205 bits (500), Expect = 1e-50
 Identities = 201/795 (25%), Positives = 321/795 (40%), Gaps = 65/795 (8%)

Query: 1291  VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
             +    +Y  K G DV +++  +  P PN  W    K I             S +L I KV
Sbjct: 26910 ISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEYSTTLIIPKV 26969

Query: 1351  ENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
                D G Y L +EN  G    + ++V +LD PS   +  +  +    + + W+ P   G 
Sbjct: 26970 TRDDTGKYLLEIENGVGEPKTITVSVKVLDTPSACNRLIVKNVTRGKLTLSWEPPYIDGG 27029

Query: 1410  STIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET- 1467
             S I  YVVE ++     +  V N    T   +  L    SY FR  A NE  + D  ET 
Sbjct: 27030 SPITNYVVEKKDAKMKAFTIVTNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETE 27089

Query: 1468  -----TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                  TE    IK+  +   T    +    T+P+ D       GG     +  Y   KK 
Sbjct: 27090 QPVRATEMPGAIKDLVLVDST-NTSVSLAWTKPDHD-------GG---SHINEYIIEKKT 27138

Query: 1523  KTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
             K  +         R               ++  A N+ G  + S +  I  K  +     
Sbjct: 27139 KDEETWSSGGTCRRCQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEA 27198

Query: 1579  DI------KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
             ++      +   ++G    +    +G P P + W K+   L+  ++      E  + + +
Sbjct: 27199 NLIDYPNGELSVRIGQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIV 27258

Query: 1633  KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             +  ++ ++ KYT+   N    +  ++ +     PS+P GP+   EI  +S+ I W  P +
Sbjct: 27259 RNARKENAGKYTLVLDNKLVKNFFDIKVITLGPPSQPIGPIRFDEIKAQSIIISWDVPQE 27318

Query: 1693  DGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             DGG E+T Y++EK E     W I  + V R   T+ I  L +  EY FRV A+N  G S+
Sbjct: 27319 DGGGEITCYSVEKRETSQAAWKIVCSSVVR--TTFKIPNLVKGTEYQFRVRAENKYGVSD 27376

Query: 1752  ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
              L S P V+      P           + ++ + + W     +GGSPI  Y +E K    
Sbjct: 27377 PLTS-PDVVAQHQYKPPGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLEKKDRNS 27435

Query: 1812  -KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTS-LPYTSDDKITIGKTLTPPS 1867
               W             R+  L     Y FR+YA+N  G S +   S  K+ I   + PP 
Sbjct: 27436 LLWMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPVSEQSKHKLAI-SPVDPPG 27494

Query: 1868  QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
              P N +  + T  SVTL+W  P+ +GGS I  Y +E +  + + W +   +  S  +  +
Sbjct: 27495 TP-NCI--DVTRDSVTLQWEPPKRDGGSRIVAYSVERRQGRAR-WLRCNFIDVSECQFTV 27550

Query: 1928  ENIKEKDEIIFRISAENTVG-VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
               +   D   FR+ A N VG VS P++S    + K  +V       +E     S  +   
Sbjct: 27551 TGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIMTKDESV----IPQIEFEAEKSLTIKA- 27605

Query: 1987  WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK------VDVNTL----KFNIRDLSENHT 2036
                    G    L  +I+ R V +  W + GK      VD+ T+       IRD   NH 
Sbjct: 27606 -------GENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDADRNHR 27658

Query: 2037  YMIRIYARNEIGLSE 2051
              +  + A+N  G ++
Sbjct: 27659 GIYTVEAKNSSGTTK 27673



 Score =  202 bits (494), Expect = 6e-50
 Identities = 180/728 (24%), Positives = 292/728 (40%), Gaps = 36/728 (4%)

Query: 1375  VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---- 1430
             +T      PPGKP I+++  SS+++ W  P++ G S +I Y VE+ ++   +W+ V    
Sbjct: 18853 ITARSPVDPPGKPEIIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNS 18912

Query: 1431  KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
             +N+ K +  +  L+  + Y+FR  A   +++S  SE ++   +I E       +   +KN
Sbjct: 18913 QNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIPIIAEHVPPRVEISLEMKN 18972

Query: 1491  -ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXX 1545
              I  +   ++ L     G P PKV W +DG  LK A   K T + +              
Sbjct: 18973 LIVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKES 19032

Query: 1546  XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPP 1601
               Y   A N  G    +  + +  KP    S   ++  H   D     W       G   
Sbjct: 19033 GEYTITAENPSGSKSANIKLKVLDKPGPPAS---VRISHVFADRVKLRWEPPLADGGSEI 19089

Query: 1602  PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
                I  K      N  +       + +   +++L   H  ++ I A N  G     VT  
Sbjct: 19090 TNYIVDKRETSRANWAQVTANINGQITDCSVEKLIEGHEYEFRISAENKYGVGDPIVTSS 19149

Query: 1662  V-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
             V     +D P   E PVI   ++R+ +T+ WK P +DG   +  Y +EK E  +  W+KV
Sbjct: 19150 VMAKNPFDVPGPCEPPVI-TNVTRDHMTVTWKAPANDGKATILGYMVEKRETQDLNWVKV 19208

Query: 1717  ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
                     T     L E  EY FRVIA N  G  +  +    V+      P         
Sbjct: 19209 NRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPVYPPGPPAFPKV 19268

Query: 1777  XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA---RIQKLSIN 1832
                 + S+ ++W     +GG  I+ Y VE K+ + ++W          A    +  L  N
Sbjct: 19269 VDSTHSSISLSWTKPAYDGGCEILGYLVEFKRADAEEWMKCNVPKNLQATKFNVTGLIDN 19328

Query: 1833  TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPE 1890
             T YQFR+ A N+IG   P    +K      L  P    +  + ++      VT++   P 
Sbjct: 19329 TEYQFRVSAVNKIGFGEPSEVPEKHLAKDILLAPEAELDADLRKALVLRAGVTMRIYVPL 19388

Query: 1891  SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
                 +P   +      +K +    I T       +C E+I   D   + ++ EN+ G   
Sbjct: 19389 RGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYC-EDINRYDAGKYVLTLENSSG--- 19444

Query: 1951  PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
              T+S ++ + K    P PP   L ++    + V  +W  P  DGG+P+  Y +  R   +
Sbjct: 19445 -TKSYTI-VVKVLDTPGPP-VNLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEKRLAER 19501

Query: 2011  TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070
               W  V      T  F I +L     Y  R+ A N  G+ E  E+  P K     G  A+
Sbjct: 19502 KAWTCVAPECPKT-SFRITNLEAGQAYCFRVLAENIYGIGEGCETAGPVKASEQPGPVAE 19560

Query: 2071  EEPGEQTE 2078
              +  E T+
Sbjct: 19561 FKSMEITK 19568



 Score =  202 bits (492), Expect = 1e-49
 Identities = 234/1090 (21%), Positives = 436/1090 (40%), Gaps = 68/1090 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP FS KP++Q V  G+ ++L           I W  + +E++      +  E++     
Sbjct: 5269 PPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNS---- 5324

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGES 751
            S L++  +K  Q   YT    N  G+ S    L +K    EPP+ +  L  + +V  G  
Sbjct: 5325 SSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVK----EPPKFVMKLDLTKLVLNGSL 5380

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK--VKDEGVYTLKAEN 809
              L  +V G+P  +I W KN   + +        T S+  L+     V+D G Y  +A +
Sbjct: 5381 ATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQASS 5440

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G    S ++TV+EP E       F+  F+   + +   + L   V+ +    I+ +++
Sbjct: 5441 DAGSDRCSCLVTVKEPPE-------FVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKD 5493

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            ++ I        +   +   L I   +   D+G Y+C   N  G++S    VT+  E  +
Sbjct: 5494 SKQIRNDRRHIISLTKDVAALQILKFEPG-DAGKYQCTVGNEVGQTSCDFLVTMK-EPPS 5551

Query: 930  FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            FV+ +  +      K V L+C  + S  ++  W  +  EI   +H +I  E +       
Sbjct: 5552 FVQKMDNT-NVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYIS 5610

Query: 988  XXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042
                   G   C  ++    Q+ + +L VKE       + +   V  +D A LE   + +
Sbjct: 5611 SVQLKHGGKYTCHAQNEAGSQKCTAVLTVKEPA-NITEQAKSVSVTVRDPATLECRYSGT 5669

Query: 1043 ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097
            +     W +DG E+   +K K        I K+     S  D GEY+  + ++    SC 
Sbjct: 5670 KVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKS--DAGEYTFEVSNDAGRSSCE 5727

Query: 1098 AEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
            A VTV++  + P    +L+  +  KG+    E  ++    + V WFK+  EI+     + 
Sbjct: 5728 AVVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKC 5787

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI-LVP 1209
                    L+I   D  D+G Y+C    + G+ +C+  L V+EP     +  PE   ++P
Sbjct: 5788 IFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPS--IIEKPESQDVIP 5845

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268
             +   +  +      L + W+K    +      ++  +    ++ +      D  +Y C 
Sbjct: 5846 GSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCE 5905

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKI 1327
            V  D  S +      V+ PPK      +  + + S + +        P+ +  W  +   
Sbjct: 5906 VSNDVGSDSCQATLFVKEPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGND 5965

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            I      K +     A L I   +  D+G+Y     N  G     M++ + + P      
Sbjct: 5966 ISPSDKYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPL 6025

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKT 1445
            + LE+ + S N  ++          + +  + ++I ++    I  KN +     +Q    
Sbjct: 6026 SPLEVVNGS-NAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDA 6084

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
                 ++    NEV    +  T      IKE     P+  + ++N+ T   + +E  C+ 
Sbjct: 6085 LDVGEYQCIVANEVGSCSSQSTLS----IKEP----PSFVERIENVVTVLGKMVEFKCVV 6136

Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGEVET 1561
             G P   + W +D   +    + + T+EN                 Y C A N+ G+ + 
Sbjct: 6137 RGSPPLSIQWQKDESWILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKC 6196

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + +Q+ P I    E I      GD       + G P  +V W K+G ++   +++++
Sbjct: 6197 FSTLVVQEPPQIIEKPEVINVT--AGDPVSFECKVSGTPELKVKWSKDGKEVIPSRQHSL 6254

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREI 1678
            +     S ++++ ++      Y  E SN       +VTL V ++   PS  +  + M EI
Sbjct: 6255 SYINNVSQLKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPPSFIKPLMEMEEI 6314

Query: 1679 SRESVTIEWK 1688
              ++V I  K
Sbjct: 6315 IGKNVQIGCK 6324



 Score =  200 bits (487), Expect = 4e-49
 Identities = 207/898 (23%), Positives = 365/898 (40%), Gaps = 57/898 (6%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249
             +EE  ++  + +    +  A  D  + + +      +VTW K    I    ++ + +   
Sbjct: 26901 LEEADVDLDISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEY 26960

Query: 1250  KRTLIIRKCTEDDQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
               TLII K T DD  +Y   +   +    T  + V+V++  P   +      + RG  +T
Sbjct: 26961 STTLIIPKVTRDDTGKYLLEIENGVGEPKTITVSVKVLD-TPSACNRLIVKNVTRGK-LT 27018

Query: 1307  LLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
             L  +  Y     P   ++V  K  K    T  + +  + +  +  +    +  +++  EN
Sbjct: 27019 LSWEPPYIDGGSPITNYVVEKKDAKMKAFTIVTNECANTTYKVDGLSEEISYFFRVSAEN 27078

Query: 1365  NCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
               G  D    E  V   + P       +++  ++S+++ W +P++ G S I  Y++E + 
Sbjct: 27079 EYGVGDPCETEQPVRATEMPGAIKDLVLVDSTNTSVSLAWTKPDHDGGSHINEYIIEKKT 27138

Query: 1422  IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-- 1479
              D   W S     + Q  +  LK  S   FR +A NE   SD S+       +KE  I  
Sbjct: 27139 KDEETWSSGGTCRRCQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPI--TVKEFLIPP 27196

Query: 1480  QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXX 1535
             ++  ++ P   ++    +++ +   + G P+P + W +D   LK ++       EN+   
Sbjct: 27197 EANLIDYPNGELSVRIGQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASL 27256

Query: 1536  XXXXXXXXXXXXYKCIAFN----DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                         Y  +  N    +  +++    +G   +P+  I  ++IK +  +   W 
Sbjct: 27257 IVRNARKENAGKYTLVLDNKLVKNFFDIKV-ITLGPPSQPIGPIRFDEIKAQSII-ISWD 27314

Query: 1592  VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNT 1650
             V     G    E+  Y    +  +   + I       +  +I  L +    ++ + A N 
Sbjct: 27315 VPQEDGG---GEITCYSVEKRETSQAAWKIVCSSVVRTTFKIPNLVKGTEYQFRVRAENK 27371

Query: 1651  AGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
              G S    S +V  +   KP  P G  ++  ++ + +T++W  P  DGG  +T Y +EK 
Sbjct: 27372 YGVSDPLTSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLEKK 27431

Query: 1707  EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
             + ++  W+KV         Y +  L E  EY FRV AQN  G S    SE    K A+  
Sbjct: 27432 DRNSLLWMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPV--SEQSKHKLAIS- 27488

Query: 1767  PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR- 1825
             P           +  +SV + W P +++GGS I+ Y VE +Q   +W           + 
Sbjct: 27489 PVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVAYSVERRQGRARWLRCNFIDVSECQF 27548

Query: 1826  -IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
              +  L+    ++FR+ ARN +GT  P +      + K  +   Q     +     +S+T+
Sbjct: 27549 TVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIMTKDESVIPQ-----IEFEAEKSLTI 27603

Query: 1885  KWTEPE----SNGGSPITNYIIEFKTVK--GKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
             K  E      S  G P+   +  +K  K   K    I TV GS     I +       I+
Sbjct: 27604 KAGENIKLSCSISGRPVPQ-VTWYKDGKEVDKMLVDITTVIGS-SSLFIRDADRNHRGIY 27661

Query: 1939  RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
              + A+N+ G    T    V +    T P PP  PL    + +      W  PE DG A +
Sbjct: 27662 TVEAKNSSG----TTKVDVLVRVQDT-PGPPEGPLRFTNISAEKATLWWSPPENDGCAAI 27716

Query: 1999  LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
               Y I  R+ ++  W  V         FN   L + + Y  R+ A N+ G+ +PLESD
Sbjct: 27717 SNYVIEKRETSRISWALVTS-KCEACSFNATKLIKGNEYQFRVSAVNKFGVGKPLESD 27773



 Score =  199 bits (486), Expect = 6e-49
 Identities = 227/1050 (21%), Positives = 434/1050 (41%), Gaps = 72/1050 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F K  +++ + +G+D++LE  +      +I+     ++I  D    +++  D+    
Sbjct: 5456 PPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDRRHIISLTKDV---- 5511

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L+I   +    G Y     N  G+ S   ++ +K    EPP  ++ + +  V   + V
Sbjct: 5512 AALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMK----EPPSFVQKMDNTNVLLAKDV 5567

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L   + G+   TI+W K++  +K    +    +  T ++  +   ++K  G YT  A+N
Sbjct: 5568 SLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQT-AVIYISSVQLKHGGKYTCHAQN 5626

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G  + +AV+TV+EP     +      +   +TV++  T++   R +   V    W ++
Sbjct: 5627 EAGSQKCTAVLTVKEPANITEQA-----KSVSVTVRDPATLE--CRYSGTKVLKAKWLKD 5679

Query: 870  -NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--DVE 926
             NE+ S  +   Q+ D  +I  +++   S  D+G+Y    SN AG+SS  A VT+   + 
Sbjct: 5680 GNELTSGRKYKIQSSDTSSILKILSAEKS--DAGEYTFEVSNDAGRSSCEAVVTVLDQII 5737

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
            K +F + L+++ E+ +G    LEC  S +  ++  W+   KEI   +  + I        
Sbjct: 5738 KPSFTRKLKET-ESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASL 5796

Query: 985  XXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                    D G   CI K+Q    + S  L VKE  P  I K +  +V         V +
Sbjct: 5797 EISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEP-PSIIEKPESQDVIPGSKVQFNVLL 5855

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
            + +    + W +D + +    +    +K      + +      D G+Y C + ++    S
Sbjct: 5856 SGTPPLTINWFKDTKEVSSGID-CSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDS 5914

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNK-ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153
            C A + V E PP+   + +   V K ++   FE ++T    +   WFKDG++I  S+  +
Sbjct: 5915 CQATLFVKE-PPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYK 5973

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209
            +T      +L+I   D+ D+G Y CE     G+  C+  L V+EP +      P  + V 
Sbjct: 5974 MTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSP--LEVV 6031

Query: 1210 ANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYT 1267
              ++AY    +      +VTW K    I+ + K  ++       TL ++KC   D  EY 
Sbjct: 6032 NGSNAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQ 6091

Query: 1268 CVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            C++  +  S +      ++ PP  V+         G  V      +  P  + +W  +  
Sbjct: 6092 CIVANEVGSCSSQSTLSIKEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDES 6151

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             I +    + + ++  A+LTI   E+  +G Y  +  N  G       + + + P    K
Sbjct: 6152 WILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEK 6211

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKT 1445
            P ++ + +    + ++   +      + +  + +E+  +   S+  I   +Q  +Q+++ 
Sbjct: 6212 PEVINVTAGD-PVSFECKVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQLKLQSVQL 6270

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
                 +     N +       T    +     +I  P+  KPL  +     +++++ C  
Sbjct: 6271 EDKGTYVFEVSNHISACQCKVTLNVLE-----QIIPPSFIKPLMEMEEIIGKNVQIGCKI 6325

Query: 1506 GGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
             G     V W +DG KL    K      EN                Y C   N  G  E 
Sbjct: 6326 SGSLPITVEWEKDGTKLSGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCEC 6385

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            S  + +++   + I N  ++ K             +G PP  V W+K+  +L        
Sbjct: 6386 SGTLRVKESQAV-IPNTTVRFK----------GSFKGTPPFTVKWFKDDTELICGPSCFT 6434

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
              +  +  + +  +  SHS  Y+ + SN A
Sbjct: 6435 GLEGLSCFLDLFAVGISHSGTYSCQISNDA 6464



 Score =  198 bits (484), Expect = 1e-48
 Identities = 180/695 (25%), Positives = 290/695 (41%), Gaps = 35/695 (5%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436
             +P PPG P +L+   SSI I W++P   G S I  Y+VE    +  EW  V     +T T
Sbjct: 21391 QPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVETCLPEEDEWTIVTPMAGLTAT 21450

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493
               +I NL  N  Y+    A+N   + + +      K   E ++  P +E      K +  
Sbjct: 21451 SFTITNLTENQEYKINISALNCEGVGEPASVPGSPKA--EDRLLPPEIELDSDLRKVVNI 21508

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYRD-GKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCI 1551
                  + L     G P P++ W R+ G+ L  A      +                Y   
Sbjct: 21509 RACSTLRLFVPVKGRPAPEIRWSREKGEPLDRASIEITPSFTTLLIENVDRFDGGKYMLT 21568

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
               N  G       V +   P     N  IK+  K  V   W    VI+G     +  Y  
Sbjct: 21569 VENSSGTKTAFINVRVLDTPGAP-QNLTIKEITKDSVSLIW-DPPVIDG--GSRIRHYIV 21624

Query: 1610  GNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEV--TLKVYD 1664
               +    K Y+I      KTS  RI +L+  +   + I A N  G    VE    +K+ +
Sbjct: 21625 EKRESTRKAYSIVNASCPKTSW-RIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISE 21683

Query: 1665  KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             +P  P G V ++E++  SVT+ W+ P  DGG  +T Y +E    ++++W +V  V   V 
Sbjct: 21684 RPLPP-GKVTLKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVK--VT 21740

Query: 1725  TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
                +  L +  EY FR+ A N  G S+    S P++ K  +  P+          +  + 
Sbjct: 21741 EAVVVGLTQGEEYSFRISATNEKGISDPRPLSVPVIAKDVVIAPAFKLLFSTFSVLAGDD 21800

Query: 1784  VYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
             + I   P      + ++  K  I  +E  +             +++ + +   ++ I   
Sbjct: 21801 LKID-VPYVAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKIT 21859

Query: 1843  NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
             N  G +   T+D  + +     PP+ P    + E T+ SVTL W  PE  GG  I NYI+
Sbjct: 21860 NSAGEA---TADINVIVLDKPGPPTGP--IKIEEVTADSVTLSWQPPEYEGGCSINNYIV 21914

Query: 1903  EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
             E +     +W +IV+   +        +K   E  FRI+AEN  G S    S+ V  +  
Sbjct: 21915 EKRDTSTTNW-QIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYP 21973

Query: 1963  ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
               +P PP  P  ++      ++  W  P  DGG+ +LGY+I  ++    +W++  K  + 
Sbjct: 21974 FEIPHPPGIPA-VQSATKESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIP 22032

Query: 2023  TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
               +F I  L E   Y  R+YA N +GLS+  +  E
Sbjct: 22033 DTRFKIGGLEEGIEYEFRVYAENIVGLSKASKVSE 22067



 Score =  198 bits (482), Expect = 2e-48
 Identities = 205/933 (21%), Positives = 370/933 (39%), Gaps = 58/933 (6%)

Query: 766  ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            + W  N K +K+        + DT+++ I K  K   EG YT +A    G   TS+ +TV
Sbjct: 4551 VNWLFNGKCIKSGKEFKCSKEHDTYTLVITKVMK-DHEGEYTCEAVGEAGKTSTSSHLTV 4609

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--IT 880
                     PP+F  R Q + V    + K    +   P  +  W+++   +  SE   I 
Sbjct: 4610 IPRV-----PPVFRQRIQNLEVNVGSSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRII 4664

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYE 939
                  ++E+    V    DSG+Y C ASN  G  S  A++T+ ++    FV     S  
Sbjct: 4665 SRHHTSSLEIFSPAV---ADSGEYTCKASNRHGSDSCSAKLTVTELFPPEFVSK-PDSMT 4720

Query: 940  TEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
               GK    +C    S  ++  W+ +   IS  DH +   +              D G  
Sbjct: 4721 LFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKNRYFLEILNLQHSDQGTY 4780

Query: 998  KCIVKDQ-ETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDG 1053
             C   +   T+T       +  P F++  +   V   +   LE +++ +T   ++W RDG
Sbjct: 4781 LCKASNSVGTATCCTELRVVDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDG 4840

Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108
            + +    + K  FE++  I  L I+ + + D G Y+C   +E    SC++ VTV E PP 
Sbjct: 4841 KKLHTTMDCKLAFEEK--IACLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQE-PPV 4897

Query: 1109 IITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
             + RL+ + + K   ++      KG  +  V WF +   +  S   ++T    +  L+I 
Sbjct: 4898 FVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEII 4957

Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPEFIL-VPANTDAYLTVEI 1220
            D    D+G Y+CEV    G   C++ +TV+E P+    LRL E +    A+ +  +T   
Sbjct: 4958 DLSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELRLVEVVKGCTAHLECEMTGTA 5017

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK 1278
            P    ++TW+K K+ +    K+ ++S      L I+     D  +Y C + +   K TTK
Sbjct: 5018 P---FEITWFKDKNPVSSDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTK 5074

Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS 1337
              V  ++ PP  V          GS V L    +       +W  +++I++    +   +
Sbjct: 5075 -AVAKLKDPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTT 5133

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
             ++  A L I  V     G Y  + EN  G    E  VT+ +      KP  + + +   
Sbjct: 5134 FENNIAVLAISNVAINHGGKYTCQAENEAGKQKCEATVTVQEPARFVEKPPCISVTAGDS 5193

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
                 +   + +  + ++    +     ++            I + +   S  ++    N
Sbjct: 5194 ATLECKVSGSPDLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSN 5253

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
             V     S +           ++ P      ++    P   + LT  F G     + W+R
Sbjct: 5254 RVGKEQCSCSINV--------LEPPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFR 5305

Query: 1518 DGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
            + K++ T    +     N                Y C   ND G+V  +  + +++ P  
Sbjct: 5306 EDKEMLTGGTCFIKKETNSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPKF 5365

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
             +   D+ +    G    +   + G P   + WYKN  ++ +D +Y +   +  + +RI 
Sbjct: 5366 -VMKLDLTKLVLNGSLATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRIS 5424

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                  S  Y  +AS+ AG+      + V + P
Sbjct: 5425 SCCVEDSGDYICQASSDAGSDRCSCLVTVKEPP 5457



 Score =  198 bits (482), Expect = 2e-48
 Identities = 221/928 (23%), Positives = 374/928 (40%), Gaps = 52/928 (5%)

Query: 1157  DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
             + ++ K+ I   + +  GE +   G+ K    L   E  ++  LR  + + + A +   L
Sbjct: 21459 ENQEYKINISALNCEGVGEPASVPGSPKAEDRLLPPEIELDSDLR--KVVNIRACSTLRL 21516

Query: 1217  TVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
              V +      ++ W ++K   E  ++ ++       TL+I      D  +Y   + ++  
Sbjct: 21517 FVPVKGRPAPEIRWSREKG--EPLDRASIEITPSFTTLLIENVDRFDGGKYMLTVENSSG 21574

Query: 1276  TTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
             T    + V V++ P    +   +   K    V+L+ D    P  +    +   I++K + 
Sbjct: 21575 TKTAFINVRVLDTPGAPQNLTIKEITK--DSVSLIWDP---PVIDGGSRIRHYIVEKRES 21629

Query: 1334  TKP--SIDSKSASLTIKKVENTDAG---IYKLRLENNCG---HADVEMNVTILDKPSPPG 1385
             T+   SI + S   T  ++ +   G    +++  EN  G     +    + I ++P PPG
Sbjct: 21630 TRKAYSIVNASCPKTSWRIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPPG 21689

Query: 1386  KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
             K  + E+ S+S+ + W++P++ G S I  Y+VE Q  ++ +W  V  +  T+  +  L  
Sbjct: 21690 KVTLKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQ 21749

Query: 1446  NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
                Y FR  A NE  ISD    +    VI +  + +P  +      +    +D+++   +
Sbjct: 21750 GEEYSFRISATNEKGISDPRPLS--VPVIAKDVVIAPAFKLLFSTFSVLAGDDLKIDVPY 21807

Query: 1506  GGVPQPKVTWYRDGKKLK-TAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
                P+  V W +DG  LK T +      E                 Y     N  GE   
Sbjct: 21808 VAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATA 21867

Query: 1562  SCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                V +  KP        I++     V   W       G      I  K      N +  
Sbjct: 21868 DINVIVLDKPGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINNYIVEKRDTSTTNWQIV 21927

Query: 1620  NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVI 1674
             + T    T+  +   LK     ++ I A N  G SSV V+  V     ++ P  P  P +
Sbjct: 21928 SATVARTTT--KAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAV 21985

Query: 1675  MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
              +  ++ES+ + W  P  DGG ++  Y IE  E ++  W+K          + I  L E 
Sbjct: 21986 -QSATKESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEG 22044

Query: 1735  CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
              EY FRV A+N VG S+A  S+   I+ A D P           +   SV + W P + +
Sbjct: 22045 IEYEFRVYAENIVGLSKA--SKVSEIQVARD-PCDPPGKPEAVIVKRSSVTLRWTPPQFD 22101

Query: 1795  GGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIG-TSLP 1850
             GG  I  Y VE K+    +W              +  L     Y+FR+ ARN  G +S+P
Sbjct: 22102 GGIKITGYVVEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVP 22161

Query: 1851  YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--TNYIIEFKTVK 1908
               S   IT    + PP    +   S++   +    +       G PI   ++I   + + 
Sbjct: 22162 SDSTGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELT 22221

Query: 1909  GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
               +  +I     +      E I+  D   + +  +N  G     E   +   K    P P
Sbjct: 22222 NTARLEIKNTDFTTTLSVKEAIR-VDGGQYTLLLKNVGG-----EKSVIINVKVLDRPGP 22275

Query: 1969  PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
             P  P+ I  V S     SW TP  DGGA +  Y +  R+ ++ +W  V ++ V TL   I
Sbjct: 22276 PDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLVWTVV-ELKVQTLNLKI 22334

Query: 2029  RDLSENHTYMIRIYARNEIGLSEPLESD 2056
               L   + Y+ R+   N+ G+ EPLESD
Sbjct: 22335 TKLLPGNEYIFRVIPVNKYGIGEPLESD 22362



 Score =  197 bits (480), Expect = 3e-48
 Identities = 201/906 (22%), Positives = 374/906 (41%), Gaps = 54/906 (5%)

Query: 1186  TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKF 1242
             T + T   P ++      + +   A     L + I   P  T++  WYK    +E   + 
Sbjct: 26497 TCVDTYGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIE--WYKDGKELESGAQI 26554

Query: 1243  TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR 1301
             ++ +  +   + +R+ T  +   Y   + ++  +    V V V+  P     E +++   
Sbjct: 26555 SISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYAAVRVLVQDKPGPPAGEIQFKKIT 26614

Query: 1302  GSDVTLLVDYQAFPQPN--DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
                +T++ D  A         +IV  +   +   +  S   +   +T+ ++   +  I++
Sbjct: 26615 ADTMTIMWDPPADEGGAMVTHYIVEKRETSRIMWSIISEKLQDCIVTVPRLIKGNEYIFR 26674

Query: 1360  LRLENNCGHAD-VEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +R  N  G  D +E    I       PS P KP +  I  S++ + W+ P   G S I  
Sbjct: 26675 VRGVNKHGVGDPLESRPVIAQNSFVHPSQPSKPQVTMITRSTMTVVWERPSLDGGSDIDG 26734

Query: 1415  YVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             Y +E +E  + +W  V    I  T+  + NL   + Y++R  A+N+      S+ + +YK
Sbjct: 26735 YYLEKREKKSLQWFKVIKDPIRDTRQKVHNLTEGNEYQYRVCAINKAGAGPYSDVSIFYK 26794

Query: 1473  VIKETKIQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY------RDGKKLKTA 1525
                     S PT  + + +  T            GG    ++T Y       D  +  T 
Sbjct: 26795 AYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGG---SEITSYVIEQRIADETEWVTI 26851

Query: 1526  KATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVET-SCVVGIQQKPVITISNEDI--- 1580
              +  E R                Y+  A N  G   +   V  +Q K ++  ++ D+   
Sbjct: 26852 SSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDILEEADVDLDIS 26911

Query: 1581  ---KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
                +   K G +  +   ++G P P V W K    +  D  Y I   E ++ + I ++ R
Sbjct: 26912 MSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEYSTTLIIPKVTR 26971

Query: 1638  SHSSKYTIEASNTAG-TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
               + KY +E  N  G   ++ V++KV D PS     +I++ ++R  +T+ W+PP  DGG 
Sbjct: 26972 DDTGKYLLEIENGVGEPKTITVSVKVLDTPSAC-NRLIVKNVTRGKLTLSWEPPYIDGGS 27030

Query: 1697  ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
              +T Y +EK +     +  V +   +  TY +  L+E   Y FRV A+N  G  +  E+E
Sbjct: 27031 PITNYVVEKKDAKMKAFTIVTNECANT-TYKVDGLSEEISYFFRVSAENEYGVGDPCETE 27089

Query: 1757  PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815
               V   A ++P             N SV + W   + +GGS I +Y +E K ++ + W  
Sbjct: 27090 QPV--RATEMPGAIKDLVLVDS-TNTSVSLAWTKPDHDGGSHINEYIIEKKTKDEETWSS 27146

Query: 1816  XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS----QPRN 1871
                       + +L   +   FR++A+NE G S  ++    IT+ + L PP        N
Sbjct: 27147 GGTCRRCQCEVTELKELSEVYFRVFAKNEKGRS-DFSQIGPITVKEFLIPPEANLIDYPN 27205

Query: 1872  FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
               +S    ++V +    P      PI  ++ +   +K     +            + N +
Sbjct: 27206 GELSVRIGQNVNIDL--PYKGKPKPIIQWMKDDVILKESEQVRFRQTENKA-SLIVRNAR 27262

Query: 1932  EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
             +++   + +  +N + V    + + + L      PS P  P+    + +  ++ SW  P+
Sbjct: 27263 KENAGKYTLVLDNKL-VKNFFDIKVITLGP----PSQPIGPIRFDEIKAQSIIISWDVPQ 27317

Query: 1992  WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
              DGG  +  Y++  R+ ++  W  V    V T  F I +L +   Y  R+ A N+ G+S+
Sbjct: 27318 EDGGGEITCYSVEKRETSQAAWKIVCSSVVRT-TFKIPNLVKGTEYQFRVRAENKYGVSD 27376

Query: 2052  PLESDE 2057
             PL S +
Sbjct: 27377 PLTSPD 27382



 Score =  195 bits (476), Expect = 1e-47
 Identities = 152/572 (26%), Positives = 237/572 (41%), Gaps = 27/572 (4%)

Query: 1415  YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS-----SYRFRAYAVNEVDISDASETTE 1469
             Y VE+++ ++  W   K  +KTQ  ++  +         Y FR  A+N   +   S TTE
Sbjct: 19846 YYVEFKDRNSLMW---KRASKTQLRVKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTE 19902

Query: 1470  YYKVIKETKIQS-PTVEKPLKN----ITTEPNED--IELT-CIFGGVPQPKVTWYRDGKK 1521
                 +        P V    +N    + T P  D   +LT  +   +  P  TW +    
Sbjct: 19903 SLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMK-ANH 19961

Query: 1522  LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
             +      Y                      A +   E     V   + +P     + ++K
Sbjct: 19962 VNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEMK 20021

Query: 1582  Q--KHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
                  K G   ++TA  I G PPP  +W K G + ++     I++   +S + IK   R 
Sbjct: 20022 DGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPTSSTLSIKYASRK 20081

Query: 1639  HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
             ++ +YTI ASN  G    +V +KV D P  P GP+    +S E  T+ W PP +DGG  +
Sbjct: 20082 NTGEYTITASNPFGIKDEKVKVKVLDVPGPP-GPIEASSVSAEKCTLTWLPPEEDGGCSI 20140

Query: 1699  TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
               Y +EK E     W K+A+   D   Y   KL +  EY+FRV A N  G  +  +S P+
Sbjct: 20141 KSYILEKRETSRLLWTKLAENVMDCR-YVASKLIKGNEYIFRVSAVNQYGTGDVTQSGPV 20199

Query: 1759  VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXX 1817
              +  +   P           +   +V I+W     +GGS I  Y VE K+  G +W    
Sbjct: 20200 KMVDSFGPPGPPSKPEIDN-VSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRWVRAS 20258

Query: 1818  XXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                    R  +  LS    Y+FR+ A N+ G   P      +       PP  P N  ++
Sbjct: 20259 KKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNPRIT 20318

Query: 1876  ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
             ++T  + T  W  P  +GG  +T YI+E K      W +  T+   + E  + N++   +
Sbjct: 20319 DTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNLQSGGK 20378

Query: 1936  IIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
               FR+SA N+ G+  P+E  Q V L     VP
Sbjct: 20379 YHFRVSALNSEGLGEPSEVEQVVELVDREEVP 20410



 Score =  194 bits (474), Expect = 2e-47
 Identities = 127/459 (27%), Positives = 209/459 (45%), Gaps = 21/459 (4%)

Query: 1596  IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             I+G P P   W K G  + + +    T++E+T ++ IKE  R  +  Y +   N  G  +
Sbjct: 29793 IKGKPLPTCKWTKEGRDISH-RAMIATSEERTELV-IKEAHRDDTGTYDLVLENKCGRKA 29850

Query: 1656  VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
             V + +KV  +P  PEGP+   +I   SV + W+PP DDGG ++  Y +E+ E     W  
Sbjct: 29851 VYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGSDIFGYIVERREVPKAAWYT 29910

Query: 1716  VADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXX 1773
             V    R V+T  + K L EN EY F++ A+N  G S++L+S E +  KT L  P      
Sbjct: 29911 VDS--RVVDTSLVVKGLKENVEYHFKITAENQFGISKSLKSDESVTPKTPLCPPEPPSFP 29968

Query: 1774  XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLS 1830
                  +   ++ ++W   + +GGS +  Y VE ++   +KW              +  L 
Sbjct: 29969 PEIMDVTKTTIGLSWSRPKDDGGSRVTGYYVERREISTEKWVRHNKTHITTTMYTLTGLI 30028

Query: 1831  INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
              +  YQFR+ A+N+IG S P    + +        P QP  F +   T  S+T+ W  PE
Sbjct: 30029 PDAEYQFRVVAQNDIGQSEPGPVSESVVCKDPFDKPGQPGEFDIISITKDSITIHWLRPE 30088

Query: 1891  SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
             S+GG  I  Y IEF+     +W K         +  I  + E  E  FR+ AEN  G+S 
Sbjct: 30089 SDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQFTIGGLMEATEYEFRVFAENETGLSR 30148

Query: 1951  PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
             P  + ++ ++   +V   P    +I+   + +           G + +L   I  R + +
Sbjct: 30149 PRRT-AMGIKTKLSVGEAPCLKEDIKDTTTKL-----------GESGILTCQIIGRPLPE 30196

Query: 2011  TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
               W   GK  + + K+ +     NH+  +    + + GL
Sbjct: 30197 IKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGL 30235



 Score =  194 bits (473), Expect = 2e-47
 Identities = 209/878 (23%), Positives = 358/878 (40%), Gaps = 52/878 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284
             + W+K    ++  E+  L +   + +L I K   D   +Y  VL ++  T K    V VV
Sbjct: 16519 IKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTRKGICTVNVV 16578

Query: 1285  EFP--PK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             + P  P+  V ++  YR          +D       N  +IV  +   +      +    
Sbjct: 16579 DRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISN--YIVEKRDTNRDLWMPVTESCT 16636

Query: 1342  SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSS 1396
               S  + K+      I ++  +N  G +D  ++     K     P  P  P + EI   +
Sbjct: 16637 RTSCKVPKLIEGREYIIRICAQNIHGISDPLLSAETKAKDVFKVPDAPQAPVVKEIYKDT 16696

Query: 1397  INICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRA 1453
               I W +P + G   I  Y+VE +E     W      +    T+  + +L     Y FR 
Sbjct: 16697 ALISWLQPAD-GGKPITNYIVEKKETKANMWARAGKDRIFPNTEYWVPDLLKGCEYEFRV 16755

Query: 1454  YAVNEVDISDASETTE--YYK---VIKETKIQSPTVEKPLKNITT--EPNEDIELTCIFG 1506
              A N + I D S +++  Y K   VI    +    ++K  +++T   +P +D     IFG
Sbjct: 16756 MAENVIGIGDPSPSSKPIYAKDPIVIPSPPVLPVAIDKTKESVTLSWQPPKDCGRGKIFG 16815

Query: 1507  GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV-- 1564
              + + +     +  ++     +  +                ++  A N  GE E + V  
Sbjct: 16816 YLLEYQKAGDEEWLQVNQTPDSCPS-TTFKVINLEDGALYRFRVKAVNAAGESEPAYVPE 16874

Query: 1565  -VGIQQK---PVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
              V  Q +   P + +     ++ K   G    + A I+G+P P+V W KN   +    E 
Sbjct: 16875 PVRAQDRFEPPELQLDLGMPRELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAE- 16933

Query: 1620  NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
              I T   T+ + ++   R+    YT+   N AG+     T+ V DKP  P   + + ++ 
Sbjct: 16934 -IETSGTTTKLEMRYCNRTDCGDYTLTVENPAGSKIATCTVLVLDKPG-PVQHLRVSDVR 16991

Query: 1680  RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
              +S  + WK P D+GG  +T + +EK +  + +W+ +    +   +   + L E   YMF
Sbjct: 16992 SDSAQLSWKDPEDNGGARITNFVVEKKDAASPQWVPICSSSKK-RSMMAKHLIEGTSYMF 17050

Query: 1740  RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             RV A+N  G SE +E+   +       P            D   V++ W   ++ GGS I
Sbjct: 17051 RVAAENQFGRSEYVETTKAIKAMNPLFPPGPPKDLHHVDADKTEVWLQWNWPDRTGGSDI 17110

Query: 1800  IDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
               + VE ++EG+K W            +  L    TY+FR+   N IG S P T+   + 
Sbjct: 17111 TGFLVEYQEEGEKDWIVFKTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRPDTTVPVLC 17170

Query: 1859  IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--TNYIIEFKTVKGKSWTKIV 1916
               K L PP    +  + E            P    G P+    ++I+ + +K +  TKI 
Sbjct: 17171 QEK-LVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKID 17229

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
             T   S     I +       I+ ++  N+ G    T S +V +     VP+ P  P+ I 
Sbjct: 17230 TDNFST-VLSIADCTRNHTGIYILTVSNSAGSK--TVSLNVTV---LDVPAAPIGPVNIL 17283

Query: 1977  MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
              V  + ++  W  P+ DGG+P++ Y +  R+  K  W  V     +T +  I  L +   
Sbjct: 17284 EVTPDSMVIDWRPPKDDGGSPVMNYIVEKRESNKETWGGVSSGSTST-RLKISRLQQGVE 17342

Query: 2037  YMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074
             Y++RI A N++G+   LES       P    H  E PG
Sbjct: 17343 YVVRIRAENKMGIGAALES------APTVARHQFEAPG 17374



 Score =  194 bits (473), Expect = 2e-47
 Identities = 183/835 (21%), Positives = 353/835 (42%), Gaps = 52/835 (6%)

Query: 1252  TLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             ++ I + T DD  +YT  L +   T  L   V+V++ P      E +   K  + +T   
Sbjct: 25876 SVTIEQATRDDSGKYTVTLQNVAGTATLTLSVKVLDSPGPPAHIEVKEVTKSSATITWDT 25935

Query: 1310  DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG 1367
                    P   ++V+ +   K   ++  I +    LT K     + G+Y  R+  EN  G
Sbjct: 25936 PDNEGGAPVKNYLVDLREATKMGWSR--ISNSCPRLTYKVTNLQEGGVYYFRVTGENEYG 25993

Query: 1368  HA---DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                  + +    I +KPSPP K  + ++   S+++ W +PE+ G S I  Y+VE  E   
Sbjct: 25994 VGVPLETKEGTKITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQ 26053

Query: 1425  TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
              +WI   +   T   +  L+ N+ Y FR  A N   +SD  +      V+ + ++++P +
Sbjct: 26054 QKWIKCGSTKSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMV--LPVLVKDQLEAPEI 26111

Query: 1485  E-KPLKNIT--TEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE---NRXXXXX 1537
               K  ++ T   +   ++++     G P PKV+  +DG+ LK T +  ++   +      
Sbjct: 26112 NMKDFQHNTAYVKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYL 26171

Query: 1538  XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAV 1595
                       Y   A N +G  ++   V +  +P   +   ++    +  V  +WL  A 
Sbjct: 26172 RESVASDAGRYDITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAY 26231

Query: 1596  IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654
               G P    I  K      N  E  +++      I+I +L      ++ I+A N  G S 
Sbjct: 26232 DGGSPITNYIVLKRETTTANWIE--VSSAVARCTIKIMKLNTGVEYQFRIKAENRFGISE 26289

Query: 1655  ---SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
                S  VT+ + Y  P  P  P +   +++ES+ + WK P  DGG  +  Y ++  + ++
Sbjct: 26290 HIDSQTVTVSLPYTLPVAPSQPWV-SAVTKESIVVNWKEPSSDGGSHVFGYHLQMKDRNS 26348

Query: 1711  NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSX 1769
               W KV         + +  +N    Y F+V A+N  G    +  S+P++   A + P+ 
Sbjct: 26349 ILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPN- 26407

Query: 1770  XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--I 1826
                      I   S+ + W     +GGS I  Y +E+K   K +W           +  +
Sbjct: 26408 ---SVRVTDITKNSISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTV 26464

Query: 1827  QKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVT 1883
               L+ N +Y+FR+ A+N +G+ S P      +T   T   P    P+ ++         T
Sbjct: 26465 SGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAGAT 26524

Query: 1884  LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI---IFRI 1940
             ++          P   +  + K ++  +    +++  +    CI +++E   +    + +
Sbjct: 26525 VQLKIGIVAKPQPTIEWYKDGKELESGAQ---ISISNTTEFTCI-SVREATRLNTGTYEL 26580

Query: 1941  SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
               +N++G +       V+ +K    P PP   ++ + + ++ +   W  P  +GGA +  
Sbjct: 26581 KIKNSLGSAYAAVRVLVQ-DK----PGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635

Query: 2001  YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
             Y +  R+ ++ MW  + +  +      +  L + + Y+ R+   N+ G+ +PLES
Sbjct: 26636 YIVEKRETSRIMWSIISE-KLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLES 26689



 Score =  192 bits (467), Expect = 1e-46
 Identities = 172/688 (25%), Positives = 281/688 (40%), Gaps = 44/688 (6%)

Query: 1315  PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
             P P+ +W  +   ++K +         S ++ IK  + +D G Y+++  N  G       
Sbjct: 14902 PPPSLKWTKDDGDLEKDRMEVEEAGQDS-TVVIKTTKRSDHGKYQIQAANPSGIKSAWTR 14960

Query: 1375  VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434
             V ++D P P      + +    + + W +P++ G S +  +++E +E     W       
Sbjct: 14961 VEVMDVPGPVLDLKPVVVTRKLMMLNWSDPDDDGGSDVTGFIIERREPKMHTWRQPIETP 15020

Query: 1435  KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT----VEKPLKN 1490
              ++  I  +     Y FR  A N+       +      V  +    SP      E+   +
Sbjct: 15021 SSKCEIVGIIEGQEYIFRVVAKNKYGCGPPVDLGPIRAVDPQGPPTSPEKFHYTERTKSS 15080

Query: 1491  ITTE--PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY 1548
             +T E  P  +   + I G + + K       +++     T +                 +
Sbjct: 15081 VTIEWRPPRNDGGSPIIGYIIEKKRQDQPAFQRVNPELCTVQ---IMTVDNLDELHMYEF 15137

Query: 1549  KCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQ------KHKVGDEWLVTAVIEGIPP 1601
             +  A N  GE E S  + +  Q   +  S   +K       + +  +   + A + G+P 
Sbjct: 15138 RAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVTGLPM 15197

Query: 1602  PEVIWYKNGNKLENDKEYNI-TTKEKTSV-----IRIKELKRSHSSKYTIEASNTAGTSS 1655
             P++ W K+   +E   E  +  TKE   V     + I  + R     YT+ ASN  GT S
Sbjct: 15198 PKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDKGTYTVTASNRLGTLS 15257

Query: 1656  VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK-----HEPDN 1710
               VT++V D+P+ P   V +  I  ES  + W  PLD GG ELT Y +E       +P+ 
Sbjct: 15258 HSVTVEVLDRPTPPRN-VAVSSIKAESCNLSWDAPLDIGGSELTNYIVEMKDLNVEDPEK 15316

Query: 1711  NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
               W++V     + + Y +  L     Y FRV A+N  G SEA E+E + IK    +P   
Sbjct: 15317 AEWVQVTKSIIE-KRYGVWNLVTGGNYKFRVKAENKYGISEACETEEVEIKDPSALPGPP 15375

Query: 1771  XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR----- 1825
                          + +TW P + +GGS I  Y +E +++G  +           R     
Sbjct: 15376 EKVTIAER-SKTHMLLTWEPPKDSGGSMITGYWLEKREKGTSYWSRVNKILVSKRGMKGW 15434

Query: 1826  ---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
                + +L     Y+FR  A N  G   P    +       LTPPS P    +++ T  SV
Sbjct: 15435 EYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADDPLTPPSMPAAPEIADKTKHSV 15494

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE---HCIENIKEKDEIIFR 1939
             TL WT P  +GG PI  YIIE +      W + V    ++H      I N+ E  +  FR
Sbjct: 15495 TLAWTPPAKDGGRPIKGYIIEIQDEGTSEWAR-VNDAENLHPSTVFTIPNLPELKKYRFR 15553

Query: 1940  ISAENTVGVSLPT-ESQSVRLEKHATVP 1966
             I A N +G S P+  +  VR+E   T P
Sbjct: 15554 IIAVNEIGESEPSPRTSEVRIEDIKTAP 15581



 Score =  191 bits (465), Expect = 2e-46
 Identities = 164/700 (23%), Positives = 292/700 (41%), Gaps = 42/700 (6%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
             P PP  P + +   +  ++ W +P   G S ++ Y+VE Q+    EW  V     I +  
Sbjct: 17473 PGPPVNPKVKDYSCTYADLVWIKPTKDGGSPVLGYIVECQK-GGAEWEKVNKDDLIKQCA 17531

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
               ++ L  ++ YRFR  AVN +   +  E  E   VI +  I  P +E      + +T  
Sbjct: 17532 YRVKGLTEDTEYRFRVKAVNMIGEGETREIPE--SVIAKDIIIPPEIEMDATCHERVTVR 17589

Query: 1495  PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXXXXXXXYKC 1550
                +I +       P P++TW +    L+  K T                       Y  
Sbjct: 17590 VGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNFPVVQMRIKEATRADHGKYVL 17649

Query: 1551  IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKN 1609
              A N+ GE   +  V +  +P      +++K  +   +  +V+    E     E+  Y  
Sbjct: 17650 KAVNEAGEASATITVNVLDRPGHC---QNLKMTYVTKNSCMVSWDAPEDNGGSEITNYIV 17706

Query: 1610  GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663
               +  + + + + + + T+ +   +L  +H   + + A N  G      T +  + +   
Sbjct: 17707 ECREPSIRTWAMISSDCTNRMVKAKLMENHEYLFRVSAENKCGPGPATETKTPILAIDPL 17766

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
              KP +PE    + +I +  V ++W+ P  DGG     Y +E+   D   W K+ +     
Sbjct: 17767 QKPGEPEN-FHVGDIGKNFVFLKWRKPDYDGGSPNLGYYLERKAKDAEAWEKLHEGVLKE 17825

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NE 1782
               + + K  EN  Y FRV + N  G S  + +  IV+K  +  P           +   E
Sbjct: 17826 TFFMVDKCVENHIYQFRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGE 17885

Query: 1783  SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
             SV +      +    P + + V+ K  G   +         ++  + K   + T ++ + 
Sbjct: 17886 SVRLE--AGLRGKPQPTVTW-VKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVT 17942

Query: 1841  ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
             A N  G+   Y +   +T+   L  P   R+  +S  ++    + W  PE +GG  + +Y
Sbjct: 17943 ATNPAGSFTAYAN---VTV---LDIPGPVRDMKISGISTDKCRVAWDPPEDDGGCEVDSY 17996

Query: 1901  IIEFKTVKGKSWTKIVTVGGS-VHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             IIE    +   W+   T   S V  +C +  + E +E IFR+ AEN +G   P ES+ + 
Sbjct: 17997 IIEKCETRRMVWS---TYSASLVTNYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPII 18053

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
              +     P PP AP E+  +G + +   W  PE DGG  + GY +  ++     W+ V K
Sbjct: 18054 AKTQYNRPGPPDAP-EVTKIGKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPVTK 18112

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               ++  +  + +L  NH Y  R+ A NE+GL EP ++  P
Sbjct: 18113 SPISERRMKVTNLIPNHDYQFRVKAENEVGLGEPSKASRP 18152



 Score =  191 bits (465), Expect = 2e-46
 Identities = 140/489 (28%), Positives = 223/489 (45%), Gaps = 24/489 (4%)

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             K G    +   I+G P PEV+WYK    L+     +I T E  +++ I E  R  + KY 
Sbjct: 20425 KSGASIRIFVPIKGRPAPEVVWYKENVPLKG--RAHIDTTESYTLVVIPECTRYDAGKYV 20482

Query: 1645  IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             +   N AG  +  V ++V D P  P   +  REI++ S+T++W+ PL DGG ++  Y IE
Sbjct: 20483 LTLENVAGKKTGFVNVRVVDTPGPPVN-LKPREITKHSITLQWEIPLIDGGSKIKNYIIE 20541

Query: 1705  KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
             K E     +  V   +    +Y I  L E  EY FRV A+N +G  E  E+ +PI    A
Sbjct: 20542 KREATRKAY-SVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIRASQA 20600

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXX 1822
                P           +  ++  + W   + +GGS I  Y +E + ++  +W         
Sbjct: 20601 PSAPDDLIVTD----VSKDTATLAWTKPKHDGGSRITGYVIEAQLKDSDQWAHVTTIKAL 20656

Query: 1823  XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
                  +L  N  Y FRI+A N  G S P  S   +   +T  P    R+       +++ 
Sbjct: 20657 DYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVAKAG 20716

Query: 1883  -TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
               LK   P      P+  +  E + +K      I     S   + I  IK KD   + ++
Sbjct: 20717 DNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILN-INEIKRKDGGQYSMT 20775

Query: 1942  AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
              +N +G    T ++++ ++ H  +P PPT P+++  V  + V+ SW  PE DGG P+  Y
Sbjct: 20776 GKNILG----TVTENITVQVH-DIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNY 20830

Query: 2002  NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-----SEPLESD 2056
              + +R+ T T WME+    + T  F    L+    Y  R+ A+N  G+     S P+ + 
Sbjct: 20831 IVEMRETTGTSWMELAATVIRT-TFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAA 20889

Query: 2057  EPFKVIPGE 2065
              PF V PG+
Sbjct: 20890 YPFDV-PGQ 20897



 Score =  190 bits (464), Expect = 3e-46
 Identities = 239/1083 (22%), Positives = 458/1083 (42%), Gaps = 77/1083 (7%)

Query: 629   LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIA-WLFKGEEIVPDENISVA 683
             L+ +P  F K+ K   + E    GS  + EC++   P   I  W+  G  +   E+    
Sbjct: 10812 LKAVPLKFVKELKDIVLQEAESIGSSAVFECQIS--PSTAITTWMKDGSNL--RESPKHK 10867

Query: 684   IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741
               SD       L+I +V+    G YT VA   N+E  ++  +++     E+ P +  + L
Sbjct: 10868 FTSDGKD--RKLQIIDVQLSDTGEYTCVAKLGNKEKTSTAKLIV-----EELPVKFTKTL 10920

Query: 742   KS-MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796
             +  M V +G+ + L+ ++  +    + W KN K +K +  K      G   S TI +   
Sbjct: 10921 EEEMSVIKGQPMYLTCEL--SKDRDVVWKKNGKELKQIAGKVQVNVIGLQRSATI-QDTN 10977

Query: 797   VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
               D GVYT + E+     +T A + + E   +    PL     ++  VK K T      +
Sbjct: 10978 DDDAGVYTCECED----IKTQANVKIIEIIRDWLTKPL-----RDQHVKPKATATFKCEL 11028

Query: 857   TRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              ++  P+  W++ +E I   P+       DG+ I L + N   + D G+Y   A    G+
Sbjct: 11029 YKD-TPNWKWFKGDEEIPTDPTNKTDVKKDGKEITLTVKNAQPD-DIGEY---AIEVEGR 11083

Query: 915   SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHRE 974
               + A++T+   +   +K L      E+G+       +   +  +W    + ++     +
Sbjct: 11084 R-YTAKLTLGEREAEILKPLASVEVVEKGEANFDTEISEDDIPGEWKLRGQVLTRSPTCD 11142

Query: 975   IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
             I  EG               G +     +  TS ML VKE   +F   L+D  V EK  A
Sbjct: 11143 IRAEGNKRFLTLKNVQLDQAGEVSYQALNAVTSAMLTVKEIEMDFTVPLRDVTVHEKKQA 11202

Query: 1035  ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
               E  I  +   V+W R  +I+   + KYD    G    L I +    DEGEY+  +  +
Sbjct: 11203 KFECTITKDVPKVLWLRGSDIVTSDQ-KYDIIDDGKKHMLVINHCEFEDEGEYTIEVLGK 11261

Query: 1095  SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
             + TA++TV  +  + ++ + +Q V +G  A FE+EL+     V W+K+ +++  S  +  
Sbjct: 11262 TSTAKLTVEGMRLKFVSPISDQTVKEGKTARFELELSHDSVPVTWYKNETKLHPSRTVLT 11321

Query: 1155  TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
              +DGKK  L+I D  LDD  +   E      TA LTV E    FT++L ++  V  + + 
Sbjct: 11322 HVDGKKHILEIKDVTLDDTCQIKAEAKGMSTTANLTVLEGDACFTVKLQDYTAVEKD-EV 11380

Query: 1215  YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
              L  E+  + + V W+  ++ I+ ++   +  + K+R L I+K  + D+  Y C     K
Sbjct: 11381 ILDCEL-SKDVPVKWFHNETEIKASKMVAIKVEGKRRILNIKKVEDKDKGLYVCDCGTDK 11439

Query: 1275  STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
             +++ L +E  +   K+V       +  G      V+       + +W +  +++      
Sbjct: 11440 TSSTLNIEARDI--KVVRPMYGVELFDGETARFEVEISE-DDVHGQWKLQGEVLSPSPDV 11496

Query: 1335  KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
             +   D    +LT+   + + +G    +  N    A++++    +   +P    ++ E D 
Sbjct: 11497 EIIEDGAKHTLTLYNCKVSQSGEVSFQGANAKCSANLKVKELPISFVTPLADVHVYEKDE 11556

Query: 1395  SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
             +       E E +  +    ++   QEI T +   +  + + +  I  +K  ++Y   A 
Sbjct: 11557 ARF-----ECEISRQAKSFRWLKGSQEIKTDDKFEL--LQEGKRHILVVKA-AAYEDEAK 11608

Query: 1455  AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
              + E +       T    VI+  +++     +P+K++T +  E  E + I     + +VT
Sbjct: 11609 YMFEAE----DNRTSAKLVIQGIRLE---FVRPIKDVTVKERETAEFS-IELSHEKVQVT 11660

Query: 1515  WYRDGKKLKTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             WY++  +L  +K  + +                    I     G+   + +  ++ +P  
Sbjct: 11661 WYKNDVRLHPSKVVHMSEDGKIHTLSFKEVSIDDTSLIKVEALGKTCEAMLTVLEGEPYF 11720

Query: 1574  TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
             T   +D     K  DE ++   +      +V W+K+GN++   K   I    K  ++ +K
Sbjct: 11721 TTKLQDYTAVEK--DEVVLMCEVSK-SSAQVKWFKDGNEITPSKNVLIKADGKKRILTVK 11777

Query: 1634  ELKRSHSSKYTIE--ASNTAGTSSVE-----VTLKVYD-KPSKPEGPVIMREISRESVTI 1685
             + ++ +  +Y  +  +  TA   ++E     +   +Y  + ++ E      EIS E V  
Sbjct: 11778 KAEKGNIGEYVCDCGSDKTAAKLNIEERDIKIVRPLYSVEVTETETARFETEISEEDVHG 11837

Query: 1686  EWK 1688
              WK
Sbjct: 11838 HWK 11840



 Score =  190 bits (464), Expect = 3e-46
 Identities = 113/368 (30%), Positives = 181/368 (49%), Gaps = 10/368 (2%)

Query: 1596  IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             I+G P P   W   G K+++  +   I T  K + + ++E     +  YT+   N +GT+
Sbjct: 29394 IKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETTIDDTGDYTLNVKNVSGTA 29453

Query: 1655  SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
             +  + + + DKP  P GP+ + E+   SVT  W+PP  DGG  ++ Y +E+ +     W+
Sbjct: 29454 TEVIRVIILDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVEQRDAHRPGWM 29513

Query: 1715  KVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
              V++ V R V  +   +L E  EY+FRV A N  G    L+SE +  K+   VP      
Sbjct: 29514 SVSESVTRPV--FKFTRLVEGTEYVFRVAATNRFGIGGFLQSEVVECKSVKTVPGAPSTP 29571

Query: 1774  XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSI- 1831
                  + ++ + +TW P E NGGS I  Y +E K+ G  +W           R +   + 
Sbjct: 29572 EILD-VSHDGMTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPVTMTRYRATGLI 29630

Query: 1832  -NTTYQFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEP 1889
                 Y++R+ A N  GT  P +++ K TI    + PP  P N  V+++T  SV+L W+ P
Sbjct: 29631 EGLEYEYRVTAINSRGTGKP-SANSKPTIAMDPIEPPGIPLNPRVTDTTRTSVSLAWSPP 29689

Query: 1890  ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
             E  GG+ +T Y+IE + V    WTK  T    + E+ + ++ +  E  FR+ A N  G  
Sbjct: 29690 EEEGGAAVTGYLIEMQKVDQVEWTKCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAG 29749

Query: 1950  LPTESQSV 1957
              P E   V
Sbjct: 29750 EPAEIPGV 29757



 Score =  189 bits (460), Expect = 8e-46
 Identities = 168/697 (24%), Positives = 294/697 (42%), Gaps = 40/697 (5%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436
             KP PP  P +  +  +S+ + W +P   G   I  Y+VE  E+ + EW+       IT+T
Sbjct: 22473 KPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITET 22532

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493
             +   + L     Y+FR  AVN++ + + ++      VI E K+++P ++      K IT 
Sbjct: 22533 RFEAKKLLEKHEYKFRICAVNKIGVGETADIPG--SVIIEDKLEAPDIDLDADLRKMITV 22590

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCI 1551
                  + L     G P P+V W + +G+  + A+    +                 Y   
Sbjct: 22591 RAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLT 22650

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
               N  G       V +   P +  +N  +K+  K+ V   W    +  G      I  K 
Sbjct: 22651 LENASGTKSAFISVRVLDTPDMP-ANFRVKEITKNSVTLTWEPPLLDGGAKIKSYIVEKR 22709

Query: 1610  GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKP 1666
              +     K Y+  T       +I+ L+      + + A N  G      T   LK+ + P
Sbjct: 22710 ES---TRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGLPAETPEPLKISEVP 22766

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
              +P G V + +++R+SV+++W+ P  DGG  +T Y +E    D ++W   A V + ++T 
Sbjct: 22767 -QPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKDQDKWSLCAQV-KALDTV 22824

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              +  L +  EY+FRVIA N  G S+  L + P+V K     P+             +  Y
Sbjct: 22825 -VTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKDLAIEPTVRTKLSTYSV---QVGY 22880

Query: 1786  ITWFPSEKNGG-SPIIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
                  +  +G   P I +  +   +KQ  +              I+  +      + I  
Sbjct: 22881 DLKIEARISGHPKPTITWNKDGSALKQTTRV-NVADTAHHTTLTIKDATREDGGMYNIVV 22939

Query: 1842  RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
              N +G      +  +I I +   PP+ P    + E ++ S+TL W  P   GG  I+NYI
Sbjct: 22940 ANVLGQQ---EATVEIIILEKPGPPTGPVR--IDEVSAESITLSWDPPTYTGGCQISNYI 22994

Query: 1902  IEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             ++ +     +W  +  TV  +  +  + N+K   E  FRI AEN  G S   +S  V  +
Sbjct: 22995 VQKRDTTTTNWVVVSATVARTTLK--VGNLKTGAEYQFRIFAENRYGKSYGIDSDPVLAQ 23052

Query: 1961  KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
                  P PP  P  +       ++  W  P  DGG+ +LGY++  ++    +W ++ K+ 
Sbjct: 23053 YPFKEPGPPGTPF-VSAFNKESMVVEWHKPVSDGGSAILGYHLERKEKNSILWTKINKIL 23111

Query: 2021  VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             +   ++    L E   Y  R+YA N +G+ +  ++ E
Sbjct: 23112 IQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSE 23148



 Score =  188 bits (457), Expect = 2e-45
 Identities = 175/705 (24%), Positives = 291/705 (41%), Gaps = 46/705 (6%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---IT 1434
             +D PS P K  +++   +SI + W +P   G S I  YV+E +  D TEW+++ +   + 
Sbjct: 26799 IDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSEITSYVIEQRIADETEWVTISSKGEVR 26858

Query: 1435  KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-- 1492
              T+  + +LK    Y +R  AVN V    + E  +   V  +  ++   V+  +   T  
Sbjct: 26859 TTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQ--PVQAKDILEEADVDLDISMSTQY 26916

Query: 1493  -TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX-----XXXXXX 1546
               +   D+E+     G P P VTW R G K  +  A Y  R                   
Sbjct: 26917 IAKAGRDVEIVIPLKGRPAPNVTW-RKGDKNISGDARYAIRNTEYSTTLIIPKVTRDDTG 26975

Query: 1547  XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ---KHKVGDEWLVTAVIEGIPPPE 1603
              Y     N  GE +T   V ++     +  N  I +   + K+   W    +  G P   
Sbjct: 26976 KYLLEIENGVGEPKT-ITVSVKVLDTPSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITN 27034

Query: 1604  VIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVT 1659
              +  K   K+   K + I T E   +  ++  L    S  + + A N  G       E  
Sbjct: 27035 YVVEKKDAKM---KAFTIVTNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETEQP 27091

Query: 1660  LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
             ++  + P   +  V++ + +  SV++ W  P  DGG  + +Y IEK   D   W      
Sbjct: 27092 VRATEMPGAIKDLVLV-DSTNTSVSLAWTKPDHDGGSHINEYIIEKKTKDEETWSSGGTC 27150

Query: 1720  DRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778
              R     C + +L E  E  FRV A+N  G S+  +  PI +K  L  P           
Sbjct: 27151 RR---CQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEANLIDYPNGE 27207

Query: 1779  ID---NESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSINT 1833
             +     ++V I   P  K    PII +  +  I +E ++ +           ++      
Sbjct: 27208 LSVRIGQNVNID-LPY-KGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKEN 27265

Query: 1834  TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESN 1892
               ++ +   N++  +     D K+    TL PPSQP   +   E  ++S+ + W  P+ +
Sbjct: 27266 AGKYTLVLDNKLVKNF---FDIKVI---TLGPPSQPIGPIRFDEIKAQSIIISWDVPQED 27319

Query: 1893  GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             GG  IT Y +E +     +W KIV          I N+ +  E  FR+ AEN  GVS P 
Sbjct: 27320 GGGEITCYSVEKRETSQAAW-KIVCSSVVRTTFKIPNLVKGTEYQFRVRAENKYGVSDPL 27378

Query: 1953  ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
              S  V  +     P PP  P+   +    + +  W  P +DGG+P+ GY++  +D    +
Sbjct: 27379 TSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTV-QWDAPGFDGGSPITGYHLEKKDRNSLL 27437

Query: 2013  WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             WM+V    ++  ++ +  L E   Y  R+YA+N  G+S   E  +
Sbjct: 27438 WMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPVSEQSK 27482



 Score =  188 bits (457), Expect = 2e-45
 Identities = 196/807 (24%), Positives = 324/807 (40%), Gaps = 60/807 (7%)

Query: 1280  KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI 1338
             K+++   P KIV+      +  G  + L +  +  P P   W     K+  K    K   
Sbjct: 29369 KIDLTGIPQKIVN------VPAGKPIVLNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIET 29422

Query: 1339  DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSI 1397
              +K   LT+++    D G Y L ++N  G A   + V ILDKP  P G   I E+D++S+
Sbjct: 29423 TAKFTKLTVRETTIDDTGDYTLNVKNVSGTATEVIRVIILDKPGVPVGPMKIEEVDATSV 29482

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAV 1456
                W+ P+  G + +  Y+VE ++     W+SV +++T+       L   + Y FR  A 
Sbjct: 29483 TCSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGTEYVFRVAAT 29542

Query: 1457  NEVDISD--ASETTEYYKVIKETKIQSPTVEKPLK------NITTEPNEDIELTCIFGGV 1508
             N   I     SE  E   V  +T   +P+  + L        +T  P ED   + I G +
Sbjct: 29543 NRFGIGGFLQSEVVECKSV--KTVPGAPSTPEILDVSHDGMTLTWTPPEDNGGSTIAGYI 29600

Query: 1509  PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
              + K         +     T                   Y+  A N  G  + S      
Sbjct: 29601 IERKEAGSDRWLSINKNPVTMTR---YRATGLIEGLEYEYRVTAINSRGTGKPSA----N 29653

Query: 1569  QKPVIT---ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNIT-T 1623
              KP I    I    I    +V D    +  +   PP E       G  +E  K   +  T
Sbjct: 29654 SKPTIAMDPIEPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVTGYLIEMQKVDQVEWT 29713

Query: 1624  KEKTSVIRIKELKRSHSS-----KYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPV-- 1673
             K  T+  +I E   +H       K+ + A N  G    + +   +KV +    P+  +  
Sbjct: 29714 KCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEK 29773

Query: 1674  IMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
             I +E  + R+   I    P+    L   K+  E  +  +   I  ++   ++    I++ 
Sbjct: 29774 IYQEGYVVRQGGVIRLSVPIKGKPLPTCKWTKEGRDISHRAMIATSEERTEL---VIKEA 29830

Query: 1732  NENCEYMFRVIAQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXIDNESVYITWFP 1790
             + +    + ++ +N  G       + + IK   +  P           I   SV ++W P
Sbjct: 29831 HRDDTGTYDLVLENKCG------RKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRP 29884

Query: 1791  SEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK-LSINTTYQFRIYARNEIGTS 1848
                +GGS I  Y VE ++  K  W          + + K L  N  Y F+I A N+ G S
Sbjct: 29885 PSDDGGSDIFGYIVERREVPKAAWYTVDSRVVDTSLVVKGLKENVEYHFKITAENQFGIS 29944

Query: 1849  LPYTSDDKITIGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
                 SD+ +T    L PP +P +F   + + T  ++ L W+ P+ +GGS +T Y +E + 
Sbjct: 29945 KSLKSDESVTPKTPLCPP-EPPSFPPEIMDVTKTTIGLSWSRPKDDGGSRVTGYYVERRE 30003

Query: 1907  VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATV 1965
             +  + W +      +   + +  +    E  FR+ A+N +G S P   S+SV  +     
Sbjct: 30004 ISTEKWVRHNKTHITTTMYTLTGLIPDAEYQFRVVAQNDIGQSEPGPVSESVVCKDPFDK 30063

Query: 1966  PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
             P  P    +I  +  + +   W  PE DGG  +LGY I  R   ++ W +  K      +
Sbjct: 30064 PGQP-GEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQ 30122

Query: 2026  FNIRDLSENHTYMIRIYARNEIGLSEP 2052
             F I  L E   Y  R++A NE GLS P
Sbjct: 30123 FTIGGLMEATEYEFRVFAENETGLSRP 30149



 Score =  187 bits (456), Expect = 3e-45
 Identities = 122/401 (30%), Positives = 183/401 (45%), Gaps = 15/401 (3%)

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             +VG+  ++ +   G P P + W+KN  +L+ ++E  +TT +    + I++ KR HS KY 
Sbjct: 16500 RVGETCIIQSRYTGKPEPTIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYM 16559

Query: 1645  IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             +   N+ GT     T+ V D+P  PEGPVI  EI R  + I W PPLDDGG  ++ Y +E
Sbjct: 16560 VVLENSIGTRKGICTVNVVDRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISNYIVE 16619

Query: 1705  KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
             K + + + W+ V   +    T C + KL E  EY+ R+ AQN  G S+ L S     K  
Sbjct: 16620 KRDTNRDLWMPV--TESCTRTSCKVPKLIEGREYIIRICAQNIHGISDPLLSAETKAKDV 16677

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXX-- 1820
               VP           I  ++  I+W     +GG PI +Y VE K+ +   W         
Sbjct: 16678 FKVPD-APQAPVVKEIYKDTALISWL-QPADGGKPITNYIVEKKETKANMWARAGKDRIF 16735

Query: 1821  -XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                   +  L     Y+FR+ A N IG   P  S   I     +  PS P   V  + T 
Sbjct: 16736 PNTEYWVPDLLKGCEYEFRVMAENVIGIGDPSPSSKPIYAKDPIVIPSPPVLPVAIDKTK 16795

Query: 1880  RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII-- 1937
              SVTL W  P+  G   I  Y++E++    + W ++     S      + I  +D  +  
Sbjct: 16796 ESVTLSWQPPKDCGRGKIFGYLLEYQKAGDEEWLQVNQTPDSCPSTTFKVINLEDGALYR 16855

Query: 1938  FRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRM 1977
             FR+ A N  G S P    + VR +       PP   L++ M
Sbjct: 16856 FRVKAVNAAGESEPAYVPEPVRAQDRF---EPPELQLDLGM 16893



 Score =  187 bits (456), Expect = 3e-45
 Identities = 228/970 (23%), Positives = 395/970 (40%), Gaps = 70/970 (7%)

Query: 1128  IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             IE+ K  +L  W +  ++     H ++T     ++ K   C ++ AG+           A
Sbjct: 27922 IEMCKA-SLEEWHRVNNQTCIQTHYRVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQA 27980

Query: 1188  ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLIS 1246
             +  +  P I+      +  +V       L +    + + + TW K    +          
Sbjct: 27981 VDRLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTD 28040

Query: 1247  DVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP--PKIVDYEREYRIKRG 1302
                  TL I  CT  D  +YT  L +   + T  L V+V++ P  P  + ++    + RG
Sbjct: 28041 TFS--TLTIENCTRYDAGKYTLSLENNSGRKTITLTVKVLDTPGPPGPLSFKD---VTRG 28095

Query: 1303  SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT--IKKVENTDAGI--- 1357
             + +TL+ D    P  +    V+  I++K + ++ S    S   T  I +V N D G+   
Sbjct: 28096 A-LTLMWDA---PSNDGGARVHHYIVEKREASRLSWQEVSERCTRQILRVINLDIGVAYF 28151

Query: 1358  YKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +++  EN  G  +  EM   I+  ++P+ P + ++++  S++ ++ W +PE+ G S I  
Sbjct: 28152 FRVTAENQYGKGEPYEMTEPIIATEEPASPKRLDVIDTTSTTASLVWMKPEHDGGSRITG 28211

Query: 1415  YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
             Y+VE ++  +  W+        +  ++ L  N+ Y FR  A N+  IS   +      +I
Sbjct: 28212 YIVETRKKGSANWVFGGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASV-II 28270

Query: 1475  KETKIQS----PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATY 1529
             KE +I+      +++K L  IT +      +     G P PKVTW  +  KLK T + + 
Sbjct: 28271 KEPRIEPTADLSSIDKQL--ITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSI 28328

Query: 1530  ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VETSCVVGIQQKPVITISNEDIKQK 1583
                ++R               Y     N  G      T  V+G    P   +    +  +
Sbjct: 28329 KISKDRTTLLVKDAKRGDSGKYYLTLENAAGSKTFTVTVIVIGRPTPPTGPVEISGVSSE 28388

Query: 1584  HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
               V   W   +   G      I  K  +     +  N + K  T  I++  L +     +
Sbjct: 28389 SCV-LTWGEPSDDGGTDITNYIVEKRESGSTTWQVVNSSVKRTT--IKVTHLTKYMEYTF 28445

Query: 1644  TIEASNTAGTS-SVE----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
              + A N  G S S+E    V    +  PS P  P ++  +   +++I W  P  DGG ++
Sbjct: 28446 RVSAENKFGVSKSIESQAIVAEHPFISPSPPTRPDVV-SVCANAISIRWDVPYHDGGSQV 28504

Query: 1699  TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEP 1757
             T Y IEK E +   W++   +      Y +  L E  EY FRV A N  G S+A E S P
Sbjct: 28505 TGYWIEKKERNTILWVRENKIPCVECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRP 28564

Query: 1758  IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK----QEGKKW 1813
             ++    +D P           +   SV I W     +GGS I+ Y VE K     E  +W
Sbjct: 28565 VLALNPVDPPG----TPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVERKASSDDEEARW 28620

Query: 1814  K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP-SQP 1869
                           +  L     Y+FR+ ARN  G  S+P  S   IT     TPP ++ 
Sbjct: 28621 LKCNYTTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKAEL 28680

Query: 1870  RNFVVSESTSRSVTLKWTEPESNGGSPITNYII---EFKTVKGKSWTKIVTVGGSVHEHC 1926
              + +V E+ S           + GG P         + +   G+ ++  +T   +     
Sbjct: 28681 DSKLVGETISIRAGSDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYS--LTYTSTRAMAI 28738

Query: 1927  IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
             I++    D   + ++ +N  G+   T + +V++      P PP   + I  V       S
Sbjct: 28739 IKSCDRNDTGRYILTVKNASGIK--TSAVNVKV---LDTPGPPAGTITISRVTDEKCTVS 28793

Query: 1987  WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
             W  P  DGG  +  Y +  R+ ++  W+ + + +  TL      L +N+ Y+ R+   N+
Sbjct: 28794 WKIPLEDGGDHVSHYIVERRETSRLNWV-IMETECKTLSCVSTKLIKNNEYIFRVRGVNK 28852

Query: 2047  IGLSEPLESD 2056
              G   PLES+
Sbjct: 28853 YGPGVPLESE 28862



 Score =  183 bits (446), Expect = 4e-44
 Identities = 168/700 (24%), Positives = 293/700 (41%), Gaps = 46/700 (6%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQ 1437
             P PP  P + +  S+++++ W  P   G + +  Y+VE ++I+  EW        +  T 
Sbjct: 24638 PGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATH 24697

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY-KVIKETKIQSPTVEKPL---KNITT 1493
              +++ LK N+ Y FR  AVN   I  A E  +    VI   K+++P +E      K +T 
Sbjct: 24698 FTVKKLKENAEYNFRICAVN---IEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTV 24754

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCI 1551
               +  + L     G P+P+V W + DG   + A+                      Y   
Sbjct: 24755 RASATLRLFVTIRGRPEPEVKWKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLT 24814

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
               N+ G       V +   P   ++ E  D+K +  V  +W    +  G      I  K 
Sbjct: 24815 LENNIGSKSAFVNVKVLDSPSAPVNFEVKDVK-RDSVQLQWEPPQIDGGAKITHYIVEKR 24873

Query: 1610  GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVT--LKVYDKP 1666
              +K       +IT     + IR+ +L+      + + A N  G     E T  +K+   P
Sbjct: 24874 ESK--RLAFTSITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKISQAP 24931

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
               P G + + +++R +VT+ W+ P  DGG ++T Y +E     +++W     +     T 
Sbjct: 24932 LPP-GKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKWTACVTIKALEAT- 24989

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
              I+ L    EY FR+ A N  G     +S+P      L  P           ID   ++ 
Sbjct: 24990 -IEGLTTGEEYSFRITAINDKG-----KSDP----KPLGAPVVARDITIEPIID--LMFN 25037

Query: 1787  TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQFRIY--ARN 1843
             T+  S K G    ID     +   +  WK          R+  L+  T  +  I    R 
Sbjct: 25038 TY--SVKAGDDLKIDVPFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATRE 25095

Query: 1844  EIGT-SLPYTSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
             + G   +  T+   +   +     L  P  P    V E ++  ++L W  P  +GG  I 
Sbjct: 25096 DAGKYEITLTNTFGVKSAEISVIVLDKPGPPGAIKVEEISADFISLSWDPPIYDGGCQIN 25155

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             NY++E +     +W +IV+   +     +  + +  E  FRI+AEN  G S   +S  + 
Sbjct: 25156 NYVVEKRDTTTTAW-QIVSATVARTSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIV 25214

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
              +   T P PPT+ L++     + ++ +W  P  DGG+P++GY+I  +D +  +W ++ +
Sbjct: 25215 AQYPFTPPGPPTS-LQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNR 25273

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               +   +F +  L E   Y  R+YA N  G+    ++ +P
Sbjct: 25274 GLITETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDP 25313



 Score =  180 bits (437), Expect = 5e-43
 Identities = 222/991 (22%), Positives = 385/991 (38%), Gaps = 97/991 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V E    ++EC  VA P  +  WL  G  +  D +  V  E    +   +  IT  +   
Sbjct: 2404 VAESQTAVMECE-VANPTSEGKWLKDGHSV--DFSDIVRSEDIDAVRRLIFVITRPQDIG 2460

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            E TY V   N +  A+L +         E  ++ + LK+  V + +  + S ++      
Sbjct: 2461 EYTYQVA--NSKTSANLRV---------EAVKIKKTLKNQTVTETQEAVFSLELTHLDVK 2509

Query: 765  TITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
               W KN    +P        DG  H++ I K    +DE VY  K     G    +A + 
Sbjct: 2510 GSQWIKNGVEIEPSDKYEITVDGLVHTLKI-KNCNSQDESVYGFKL----GKLSANARLN 2564

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            VE  T +  + P      +++T    GT      ++ + +P + W   N+ + PS  +  
Sbjct: 2565 VE--TIKIVKKP------KDVTSLVNGTASFELSLSHDDIP-VKWMFKNQELKPSANVQI 2615

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
              + +  +LVI NV+ E + G+Y  V  +            + VE +   K L K+ E  
Sbjct: 2616 MSERKAHKLVIQNVE-ESNDGEYTAVVGHLQ------CSAYLHVESLRVTKPL-KNLEVP 2667

Query: 942  EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            E      EC+ SH  V + W  N  EI   +   I+ +G+            D      +
Sbjct: 2668 ETHVATFECEVSHFNVPSTWLKNGVEIEMSEKFRIVVQGKLHQLKIMNTSRDDSAEYTFV 2727

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
              + + S  L V   +      L+D   +EKD    EV +N E     W ++G  I+   
Sbjct: 2728 CGNDKVSATLTVSPVL--ITSMLKDLNAQEKDTITFEVTVNYEGITYKWLKNGVEIR-SS 2784

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
            ++     +     L IRN    D G+Y  +       A++ V     E    +++ KV +
Sbjct: 2785 DRCQTRTKQLSHSLTIRNVHFGDVGDYKFVAGSAETAAKLFVEARVIEFTKHIKDIKVTE 2844

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
              KA FE EL++ +  V W KDG E++ S   +++ +    +L I    + DAGEYS   
Sbjct: 2845 KKKAVFECELSEPNVQVTWMKDGQELELSERYKVSTERHVHRLMIQTVRMSDAGEYSVVA 2904

Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT- 1239
            G+S   A LTVE   +  +    + I V     +    E+ ++ ++  W +    I+ + 
Sbjct: 2905 GSSVSKANLTVEGKDVRISEPAEKEITVLEKQRSTFEFEVNEDDIEGRWLRNGVEIQFSV 2964

Query: 1240 -EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298
             ++F      K   L I +    D  EYT +    +S   L V + E PP+I+ + +   
Sbjct: 2965 DQRFNYAIIRKIHRLTITETYRSDAGEYTFIAGKNRSIVTLHVNIPE-PPQIIRHMQPLS 3023

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK---KCKHTKPSIDSKSASLTIKKVENTDA 1355
            ++ G      V+    PQP   W  NS+ +    KCK  +   +    +L + +V   DA
Sbjct: 3024 VEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLR---EGNEHTLLLIEVFPEDA 3080

Query: 1356 GIYKLRLENNCGHA--DVEMNVTILDKPSP----PGKPNIL--EIDSSSIN---ICWDEP 1404
              Y    +N+ G A     +NV + +  SP    P  P ++   I ++S N       + 
Sbjct: 3081 AQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQC 3140

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE----- 1458
              +G    I +  + +EI  ++   V    +  Q  I  +       +   A N      
Sbjct: 3141 RVSGEDLTITWYCKDKEIKQSDIFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVS 3200

Query: 1459 ----VDISDASETTEYYKVIKETKIQSP-----TVEK-----------PLKNITTEPNED 1498
                + +   +E  +Y          SP     T++K           P+ +      E 
Sbjct: 3201 CSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTIQKDAIGQKPSFFQPIMSSVVAHGEV 3260

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE-----NRXXXXXXXXXXXXXXXYKCIA 1552
                    G+P+P+++W+ + + +K T    Y      N                Y C A
Sbjct: 3261 ARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKA 3320

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583
             N  GE   S  + + ++  +T   E+I+ K
Sbjct: 3321 VNIRGEAACSANLAVTEE--VTRVREEIEAK 3349



 Score =  179 bits (436), Expect = 7e-43
 Identities = 213/911 (23%), Positives = 361/911 (39%), Gaps = 70/911 (7%)

Query: 1192  EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250
             E P +   L +P  +   A T   +   I       VTW K ++ +    +        K
Sbjct: 16883 EPPELQLDLGMPRELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETSGTTTK 16942

Query: 1251  RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
               L +R C   D  +YT  + + A S       +V   P  V + R   ++  S      
Sbjct: 16943 --LEMRYCNRTDCGDYTLTVENPAGSKIATCTVLVLDKPGPVQHLRVSDVRSDSAQLSWK 17000

Query: 1310  DYQAFPQPNDEWIVNSKIIKKCKHTKPS-----IDSKSASLTIKKVENTDAGIYKLRLEN 1364
             D    P+ N    + + +++K     P        SK  S+  K +    + ++++  EN
Sbjct: 17001 D----PEDNGGARITNFVVEKKDAASPQWVPICSSSKKRSMMAKHLIEGTSYMFRVAAEN 17056

Query: 1365  NCGHAD-VEMNVTI--LDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVE 1418
               G ++ VE    I  ++   PPG P  L   + D + + + W+ P+ TG S I  ++VE
Sbjct: 17057 QFGRSEYVETTKAIKAMNPLFPPGPPKDLHHVDADKTEVWLQWNWPDRTGGSDITGFLVE 17116

Query: 1419  YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             YQE    +WI  K ++  +  +  L+   +YRFR    N + +S    T     V+ + K
Sbjct: 17117 YQEEGEKDWIVFKTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRPDTTV---PVLCQEK 17173

Query: 1479  IQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYEN- 1531
             +  P VE   K ++ I  +    I L  +  G+P P   W  DG+++K+    K   +N 
Sbjct: 17174 LVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKIDTDNF 17233

Query: 1532  RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDE 1589
                             Y     N  G    S  V +   P   I   +I +     +  +
Sbjct: 17234 STVLSIADCTRNHTGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILEVTPDSMVID 17293

Query: 1590  WLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEA 1647
             W       G P    I      K E++KE    +++   ++ ++I  L++       I A
Sbjct: 17294 WRPPKDDGGSPVMNYI----VEKRESNKETWGGVSSGSTSTRLKISRLQQGVEYVVRIRA 17349

Query: 1648  SNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
              N  G      S+  V    ++ P  P  PV   ++S +++T+ W  PL DGG  ++ Y 
Sbjct: 17350 ENKMGIGAALESAPTVARHQFEAPGHPGKPV-ASDLSEDALTLGWTMPLFDGGSPISGYI 17408

Query: 1703  IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIK 1761
             IE+      +WI+V         Y +  L E  EY FRV A+N  GFS  +  S+P    
Sbjct: 17409 IERRH-KGGKWIRVNKTPCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSPVSDPAKPC 17467

Query: 1762  TALDVPSXXXXXXXXXXIDNESVY--ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX 1819
               + VP            D    Y  + W    K+GGSP++ Y VE ++ G +W+     
Sbjct: 17468 RPITVPGPPVNPKVK---DYSCTYADLVWIKPTKDGGSPVLGYIVECQKGGAEWEKVNKD 17524

Query: 1820  XXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     R++ L+ +T Y+FR+ A N IG        + +     + PP       +  
Sbjct: 17525 DLIKQCAYRVKGLTEDTEYRFRVKAVNMIGEGETREIPESVIAKDIIIPP----EIEMDA 17580

Query: 1877  STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK-----IVTVGGSVHEHCIENIK 1931
             +    VT++     +  G        E    KG+S  +     ++T    V +  I+   
Sbjct: 17581 TCHERVTVRVGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNFPVVQMRIKEAT 17640

Query: 1932  EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
               D   + + A N  G +  T + +V L++     +     L++  V  N  M SW  PE
Sbjct: 17641 RADHGKYVLKAVNEAGEASATITVNV-LDRPGHCQN-----LKMTYVTKNSCMVSWDAPE 17694

Query: 1992  WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
              +GG+ +  Y +  R+ +   W  +     N  +     L ENH Y+ R+ A N+ G   
Sbjct: 17695 DNGGSEITNYIVECREPSIRTWAMISSDCTN--RMVKAKLMENHEYLFRVSAENKCGPGP 17752

Query: 2052  PLESDEPFKVI 2062
               E+  P   I
Sbjct: 17753 ATETKTPILAI 17763



 Score =  176 bits (428), Expect = 6e-42
 Identities = 208/934 (22%), Positives = 376/934 (40%), Gaps = 65/934 (6%)

Query: 1157  DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
             +  +   +I   +++ AGE+    G+      L   E  ++  LR    +   A    ++
Sbjct: 24705 ENAEYNFRICAVNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFV 24764

Query: 1217  TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AK 1274
             T+    E  +V W K    + +  +  +        L+I      D  +Y   L +    
Sbjct: 24765 TIRGRPEP-EVKWKKADGTLPERAQIEVTGSYTG--LVIDNVNRFDTGKYVLTLENNIGS 24821

Query: 1275  STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND------EWIVNSKII 1328
              +  + V+V++ P   V++E +  +KR S     V  Q  P   D       +IV  +  
Sbjct: 24822 KSAFVNVKVLDSPSAPVNFEVK-DVKRDS-----VQLQWEPPQIDGGAKITHYIVEKRES 24875

Query: 1329  KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDKPSP 1383
             K+   T  SI +     +I+  +  + G+Y  R+   N  G    A+    V I   P P
Sbjct: 24876 KRLAFT--SITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKISQAPLP 24933

Query: 1384  PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL 1443
             PGK  ++++   ++ + W++P++ G S I  Y+VE     + +W +   I   + +I+ L
Sbjct: 24934 PGKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKWTACVTIKALEATIEGL 24993

Query: 1444  KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
              T   Y FR  A+N+   SD         V ++  I+ P ++      + +  +D+++  
Sbjct: 24994 TTGEEYSFRITAINDKGKSDPKPLGAPV-VARDITIE-PIIDLMFNTYSVKAGDDLKIDV 25051

Query: 1504  IFGGVPQPKVTWYRDGKKLK-TAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHG-- 1557
              F G P P+VTW +DG  LK T +    T +                 Y+    N  G  
Sbjct: 25052 PFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFGVK 25111

Query: 1558  EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
               E S +V  +  P   I  E+I     +   W       G      +  K  +      
Sbjct: 25112 SAEISVIVLDKPGPPGAIKVEEISADF-ISLSWDPPIYDGGCQINNYVVEKR-DTTTTAW 25169

Query: 1618  EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMR 1676
             +    T  +TS I++  L +    ++ I A N  G S +++    V   P  P GP    
Sbjct: 25170 QIVSATVARTS-IKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIVAQYPFTPPGPPTSL 25228

Query: 1677  EIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733
             ++S   +  + + W  P  DGG  +  Y IE  +  +  W K+         + +  L E
Sbjct: 25229 QVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNRGLITETQFKVTGLEE 25288

Query: 1734  NCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
               +Y +RV A+N  G     ++ +P+  +     PS          I   SV ++W   E
Sbjct: 25289 GLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPS----QPRVMNITRTSVSLSWTKPE 25344

Query: 1793  KNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-S 1848
              +GG+ +  Y VE  +  +G+  K            +  L  +  Y FRI A+N  G  S
Sbjct: 25345 FDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRYDFRIIAKNAAGLFS 25404

Query: 1849  LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-----PESNGGS-PITNYII 1902
              P  S   +T+   + PP       + +   + V +K  E      E +G   P+ ++  
Sbjct: 25405 EPSESTGPVTVKDDVDPP----RITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAK 25460

Query: 1903  EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
             + K ++ K+  +I +   S     + +   +D   + ++ +N  G    T S +V   K 
Sbjct: 25461 DGKEIEAKARFEISSTLTST-TLIVRDAIRRDSGQYVLTLQNVAG----TRSLAVNC-KV 25514

Query: 1963  ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
                P P + PL+I  + +     +WG P+ +GGA +  Y +  R+ ++  W  V   D+ 
Sbjct: 25515 LDRPGPSSGPLDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLV-YADMK 25573

Query: 2023  TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
                  +  L + + Y+ R+   N+ G  E LESD
Sbjct: 25574 ATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESD 25607



 Score =  175 bits (426), Expect = 1e-41
 Identities = 196/849 (23%), Positives = 334/849 (39%), Gaps = 56/849 (6%)

Query: 1244  LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TK-LKVEVVEFPPKIVDYEREYRIKR 1301
             L+SD +K +L I++   DD   YT    ++  T TK +K+ ++  P   V       IK 
Sbjct: 15946 LVSD-EKCSLFIQQSKRDDSAMYTLTATNSLGTATKSIKLSILGRPGVPVG-----PIKI 15999

Query: 1302  GSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDA 1355
             G      +     P  +D    I N  + K+ ++ K     S D K     ++++     
Sbjct: 16000 GEVFAERIGLSWNPPADDGGSKITNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHE 16059

Query: 1356  GIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
               +++  +N  G     +++ E    +   P PP  P + +   S++++ W  P N G S
Sbjct: 16060 YEFRVMAQNKYGVGPPLYSEPEKARNLFTPPGPP-TPKVTDCTKSTVDLEWIPPLNDGGS 16118

Query: 1411  TIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
              I  Y VEY++    EW  VK+  I  T+  +  LK    YRFR  AVN   + +  E  
Sbjct: 16119 MITGYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVA 16178

Query: 1469  EYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTA 1525
             +  +V   T      ++  +K  I       I +     G P P++ W RD  +L  + A
Sbjct: 16179 DVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAA 16238

Query: 1526  KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---VITISNEDIKQ 1582
               T                   Y   A N  GE + + +V +   P    +  S E++  
Sbjct: 16239 VETTSISSALVIKSCLRQHQGIYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENL-T 16297

Query: 1583  KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
                    W       G      I  K             T     +V  ++ L       
Sbjct: 16298 NDSCKLTWYSPEDDGGSAITNYIIEKREADRRGWTSVTYTVTRHNAV--VQGLIDGKGYF 16355

Query: 1643  YTIEASNTAGTSSVEVT---LKVYDKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLE 1697
             + I A N  G      T   + + D  S PE P  V +  I+ +S+++ W+ P  DGG +
Sbjct: 16356 FRIAAENIIGMGPFTETAAPVVIKDPLSVPERPEDVEVTAITNDSISVAWRSPKYDGGSD 16415

Query: 1698  LTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSE-ALES 1755
             +T Y +E      + + ++A  D+ ++  +    L E   Y FRV A N +G  + +  +
Sbjct: 16416 ITSYVLEVRLIGQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFST 16475

Query: 1756  EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDY--KVEIKQEGKK 1812
             +P+  K   + P+          +      I    S   G   P I +    E  Q  ++
Sbjct: 16476 KPVTCKKEFEPPNLDLEFRDKLVVRVGETCI--IQSRYTGKPEPTIKWFKNDEELQANEE 16533

Query: 1813  WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                          I+K   + + ++ +   N IGT     +   + +     PP  P   
Sbjct: 16534 IALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTRKGICT---VNVVDRPQPPEGP--V 16588

Query: 1873  VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIK 1931
             +  E     + + W  P  +GG+ I+NYI+E +      W  +          C +  + 
Sbjct: 16589 IFDEIYRNYMVISWNPPLDDGGAAISNYIVEKRDTNRDLWMPVTE--SCTRTSCKVPKLI 16646

Query: 1932  EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
             E  E I RI A+N  G+S P  S   + +    VP  P AP+ ++ +  +  + SW  P 
Sbjct: 16647 EGREYIIRICAQNIHGISDPLLSAETKAKDVFKVPDAPQAPV-VKEIYKDTALISWLQPA 16705

Query: 1992  WDGGAPLLGYNIAIRDVTKTMWMEVGK--VDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
              DGG P+  Y +  ++    MW   GK  +  NT ++ + DL +   Y  R+ A N IG+
Sbjct: 16706 -DGGKPITNYIVEKKETKANMWARAGKDRIFPNT-EYWVPDLLKGCEYEFRVMAENVIGI 16763

Query: 2050  SEPLESDEP 2058
              +P  S +P
Sbjct: 16764 GDPSPSSKP 16772



 Score =  174 bits (424), Expect = 2e-41
 Identities = 177/702 (25%), Positives = 283/702 (40%), Gaps = 47/702 (6%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS- 1439
             PS P    +++   +S+ + W +P   G   II Y++E  +    EW  V N T  QT  
Sbjct: 27886 PSAPTLVKVIDSTKTSVTLAWTKPVFDGGLEIIGYIIEMCKASLEEWHRVNNQTCIQTHY 27945

Query: 1440  -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
              +  L++   Y+FR  AVN     + SET    + +         ++   K      N  
Sbjct: 27946 RVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGG 28005

Query: 1499  -IELTCIFGGVPQPKVTWYR-DGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
              ++L   F G P P  TW + DG   +     T +                 Y     N+
Sbjct: 28006 TVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENN 28065

Query: 1556  HGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
              G    +  V +   P     +S +D+  +  +   W   +   G      I  K     
Sbjct: 28066 SGRKTITLTVKVLDTPGPPGPLSFKDVT-RGALTLMWDAPSNDGGARVHHYIVEKREASR 28124

Query: 1614  ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
              + +E  ++ +    ++R+  L    +  + + A N  G        +      +P  P 
Sbjct: 28125 LSWQE--VSERCTRQILRVINLDIGVAYFFRVTAENQYGKGEPYEMTEPIIATEEPASPK 28182

Query: 1674  IMREISRESVT--IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
              +  I   S T  + W  P  DGG  +T Y +E  +  +  W+      + ++   ++ L
Sbjct: 28183 RLDVIDTTSTTASLVWMKPEHDGGSRITGYIVETRKKGSANWV-FGGQTKSLKMV-LEGL 28240

Query: 1732  NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
              EN EY FRV AQN  G S+  ++   ++IK     P+          ID + +      
Sbjct: 28241 VENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSS-----IDKQLITC---- 28291

Query: 1791  SEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQ-KLSIN-TTYQFRIYARNEIGT 1847
               K G S  ID  +  +   K  WK          R+  K+S + TT   +   R + G 
Sbjct: 28292 --KTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDAKRGDSGK 28349

Query: 1848  ---SLPYTSDDK------ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
                +L   +  K      I IG+  TPP+ P    +S  +S S  L W EP  +GG+ IT
Sbjct: 28350 YYLTLENAAGSKTFTVTVIVIGRP-TPPTGPVE--ISGVSSESCVLTWGEPSDDGGTDIT 28406

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQS 1956
             NYI+E +     +W     V  SV    I+  ++ +  E  FR+SAEN  GVS   ESQ+
Sbjct: 28407 NYIVEKRESGSTTWQ---VVNSSVKRTTIKVTHLTKYMEYTFRVSAENKFGVSKSIESQA 28463

Query: 1957  VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
             +  E     PSPPT P ++  V +N +   W  P  DGG+ + GY I  ++    +W+  
Sbjct: 28464 IVAEHPFISPSPPTRP-DVVSVCANAISIRWDVPYHDGGSQVTGYWIEKKERNTILWVRE 28522

Query: 2017  GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              K+      + +  L E   Y  R+YA N  GLS+  E   P
Sbjct: 28523 NKIPCVECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRP 28564



 Score =  173 bits (422), Expect = 3e-41
 Identities = 184/722 (25%), Positives = 288/722 (39%), Gaps = 51/722 (7%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---- 1433
             L  PS P  P I +    S+ + W  P   G   I  Y++E Q+  T+EW  V +     
Sbjct: 15475 LTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEIQDEGTSEWARVNDAENLH 15534

Query: 1434  TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KN 1490
               T  +I NL     YRFR  AVNE+  S+ S  T   + I++ K  +P +   +   + 
Sbjct: 15535 PSTVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVR-IEDIK-TAPKIFMDISADEL 15592

Query: 1491  ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550
             +        ++     G P PKVTW  DGK     K                        
Sbjct: 15593 LCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTSVVTVP 15652

Query: 1551  IAFNDH-GEVETSCVVGIQQKPV-ITISNEDI---KQKHKVGDEWLVT-AVIEGIPPPE- 1603
             ++   H G    +      QK V + ++  D+    ++ KV D    T  +I  +P  + 
Sbjct: 15653 VSLRSHSGRYTITAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMRLIWKLPDNDG 15712

Query: 1604  ---VIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS-VEV 1658
                +  Y    K  N K + +      S+   +  L       + + A N  G     E 
Sbjct: 15713 GERIKSYFIEKKAVNGKAWTVANATCASMAFVVSNLLEGQDYFFRVRAENRLGFGPFTET 15772

Query: 1659  TLKVYDK----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK-----HEPD 1709
             T  V  +    P  P   V +  +++ +VT+ W PP +DGG  +  Y IE+       P 
Sbjct: 15773 TEPVRARDPIYPPDPPTKVKINLVTKNTVTLTWVPPKNDGGAPVKHYIIERLSWDTSGPQ 15832

Query: 1710  NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768
                W +    D +  T+ I+ L E  EY FRV A N  G S  ++ + PIVIK     PS
Sbjct: 15833 KETWKQCNKRDVEETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPS 15892

Query: 1769  XXXXXXXXXXIDNESVYITW------FPSEKNGGSP--IIDYKVEIKQEGKKWKXXXXXX 1820
                        +   V I        FPS     +P    D KV + Q  K         
Sbjct: 15893 IDLREALEGA-EGFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPV-QYDKHVNKLVSDE 15950

Query: 1821  XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTS 1879
                  IQ+   + +  + + A N +GT+   T   K++I   L  P  P   + + E  +
Sbjct: 15951 KCSLFIQQSKRDDSAMYTLTATNSLGTA---TKSIKLSI---LGRPGVPVGPIKIGEVFA 16004

Query: 1880  RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
               + L W  P  +GGS ITNY++E +    K+W   V+      ++ ++ + E  E  FR
Sbjct: 16005 ERIGLSWNPPADDGGSKITNYVVEKREENRKTWVH-VSSDPKECQYIVQRLTEGHEYEFR 16063

Query: 1940  ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
             + A+N  GV  P  S+  +     T P PPT   ++     + V   W  P  DGG+ + 
Sbjct: 16064 VMAQNKYGVGPPLYSEPEKARNLFTPPGPPTP--KVTDCTKSTVDLEWIPPLNDGGSMIT 16121

Query: 2000  GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
             GY +  +   +  W +V   ++   KF +  L E   Y  R+ A N  G+ EP E  +  
Sbjct: 16122 GYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVI 16181

Query: 2060  KV 2061
             +V
Sbjct: 16182 EV 16183



 Score =  173 bits (420), Expect = 6e-41
 Identities = 166/712 (23%), Positives = 286/712 (40%), Gaps = 53/712 (7%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT-----EW--ISVKNI 1433
             P PP K  I  +  +++ + W  P+N G + + +Y++E    DT+      W   + +++
Sbjct: 15785 PDPPTKVKINLVTKNTVTLTWVPPKNDGGAPVKHYIIERLSWDTSGPQKETWKQCNKRDV 15844

Query: 1434  TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
              +T   I++LK    Y FR  AVNE   S  S T     +  +T   S  + + L+    
Sbjct: 15845 EETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGAE- 15903

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYR------DGK-----KLKTAKATYENRXXXXXXXXXX 1542
                 D+ +     G P P + W++      D K          K   + +          
Sbjct: 15904 --GFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKR 15961

Query: 1543  XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIP 1600
                  Y   A N  G    S  + I  +P + +    I +    ++G  W   A   G  
Sbjct: 15962 DDSAMYTLTATNSLGTATKSIKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGG-- 16019

Query: 1601  PPEVIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----S 1654
               ++  Y    + EN K + ++++  K     ++ L   H  ++ + A N  G      S
Sbjct: 16020 -SKITNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPPLYS 16078

Query: 1655  SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
               E    ++  P  P   V   + ++ +V +EW PPL+DGG  +T Y +E  +     W 
Sbjct: 16079 EPEKARNLFTPPGPPTPKVT--DCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWE 16136

Query: 1715  KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
             KV D +     + +  L E   Y FRV A N  G  E  E   ++      +P       
Sbjct: 16137 KVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPE----- 16191

Query: 1775  XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT 1834
                 +D ++           G   I+ Y          W          A ++  SI++ 
Sbjct: 16192 ----VDLDATVKEKIVVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAAVETTSISSA 16247

Query: 1835  YQFRIYARNEIGTSLPYTSD-----DKITIGKTLTPPSQPR-NFVVSESTSRSVTLKWTE 1888
                +   R   G       +      K  I + L  P      F     T+ S  L W  
Sbjct: 16248 LVIKSCLRQHQGIYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYS 16307

Query: 1889  PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
             PE +GGS ITNYIIE +    + WT  VT   + H   ++ + +     FRI+AEN +G+
Sbjct: 16308 PEDDGGSAITNYIIEKREADRRGWTS-VTYTVTRHNAVVQGLIDGKGYFFRIAAENIIGM 16366

Query: 1949  SLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
                TE+ + V ++   +VP  P   +E+  + ++ +  +W +P++DGG+ +  Y + +R 
Sbjct: 16367 GPFTETAAPVVIKDPLSVPERPE-DVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRL 16425

Query: 2008  VTKTMWMEVGKVD-VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             + +  +  + K D +   KF    L E  +Y  R+ A N+IG  +P  S +P
Sbjct: 16426 IGQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKP 16477



 Score =  171 bits (417), Expect = 1e-40
 Identities = 197/895 (22%), Positives = 345/895 (38%), Gaps = 52/895 (5%)

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252
             P +  +L +   I+V A  +  L  E+  + +  V W K  + ++  E   +   V   +
Sbjct: 18962 PRVEISLEMKNLIVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLS 19021

Query: 1253  LIIRKCTEDDQCEYTCVLLD---AKSTT-KLKVEVVEFPPKIVDYEREY--RIKRGSDVT 1306
             L +   T  +  EYT    +   +KS   KLKV     PP  V     +  R+K   +  
Sbjct: 19022 LELFSVTRKESGEYTITAENPSGSKSANIKLKVLDKPGPPASVRISHVFADRVKLRWEPP 19081

Query: 1307  LLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
             L             +IV+ +   +    +   +I+ +    +++K+       +++  EN
Sbjct: 19082 LADGGSEITN----YIVDKRETSRANWAQVTANINGQITDCSVEKLIEGHEYEFRISAEN 19137

Query: 1365  NCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
               G  D  +  +++     D P P   P I  +    + + W  P N G +TI+ Y+VE 
Sbjct: 19138 KYGVGDPIVTSSVMAKNPFDVPGPCEPPVITNVTRDHMTVTWKAPANDGKATILGYMVEK 19197

Query: 1420  QEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +E     W+ V        +I+   L   + Y FR  A+N+  +   S+ +     +   
Sbjct: 19198 RETQDLNWVKVNRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPV 19257

Query: 1478  KIQSP-----TVEKPLKNIT---TEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAK 1526
                 P      V+    +I+   T+P  D     I G + + K     +  K    K  +
Sbjct: 19258 YPPGPPAFPKVVDSTHSSISLSWTKPAYDGGCE-ILGYLVEFKRADAEEWMKCNVPKNLQ 19316

Query: 1527  ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKH- 1584
             AT  N                   I F +  EV E      I   P   + + D+++   
Sbjct: 19317 ATKFNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPEKHLAKDILLAPEAEL-DADLRKALV 19375

Query: 1585  -KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
              + G    +   + G P P+  W K    L+  +   I T E  + +  +++ R  + KY
Sbjct: 19376 LRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYDAGKY 19435

Query: 1644  TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
              +   N++GT S  + +KV D P  P   +I++E S++ V+I W  PL DGG  +  Y +
Sbjct: 19436 VLTLENSSGTKSYTIVVKVLDTPGPPVN-LIVKETSKDHVSITWDAPLIDGGSPVKSYVV 19494

Query: 1704  EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
             EK   +   W  VA  +    ++ I  L     Y FRV+A+N  G  E  E+   V   A
Sbjct: 19495 EKRLAERKAWTCVAP-ECPKTSFRITNLEAGQAYCFRVLAENIYGIGEGCETAGPV--KA 19551

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXX 1823
              + P           I   S  + W     +GGS ++ Y +EI +   KWK         
Sbjct: 19552 SEQPG-PVAEFKSMEITKNSCTLGWKKPISDGGSHVVAYALEICEGEDKWKLLMKSKVTQ 19610

Query: 1824  ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRS 1881
               I  L     Y FR+ A NE     P  ++  I     + PP+     +   S      
Sbjct: 19611 YTIGDLVEGKEYSFRVKAINESAEGPP--TELTILAKDQIVPPNCDLKGLPDSSYVAKEG 19668

Query: 1882  VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
              T++   P +   +P   +     T+       + +   +     I +    D   F I 
Sbjct: 19669 TTVRLNIPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNT-VLLIRDCHRGDAGKFTII 19727

Query: 1942  AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
               N+ G    T+  ++ + K    P   + P++   + +  +   WG P+ DGG+ +  Y
Sbjct: 19728 LRNSAG----TKEAAIDI-KVVGKPGICSGPIKFDEITAEAITVEWGPPKDDGGSEVTNY 19782

Query: 2002  NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
              +  R  T   W+ V    +      +  L +   Y+ R+ A N+ G+ E L SD
Sbjct: 19783 FLEKRHSTANKWVTVASA-IQKNSMRVTRLHDGTEYIFRVCAENKYGIGEFLRSD 19836



 Score =  171 bits (416), Expect = 2e-40
 Identities = 186/785 (23%), Positives = 303/785 (38%), Gaps = 72/785 (9%)

Query: 1358  YKLRLENNCGHADVE---MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +++  +NN G + V     +   +    PPG PN +++   S+ + W+ P+  G S I+ 
Sbjct: 27464 FRVYAQNNAGMSPVSEQSKHKLAISPVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVA 27523

Query: 1415  YVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471
             Y VE ++     W+     ++++ Q ++  L     + FR  A N V  +S  S+++ Y 
Sbjct: 27524 YSVERRQ-GRARWLRCNFIDVSECQFTVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYI 27582

Query: 1472  KVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKA 1527
                 E+ I  P +E +  K++T +  E+I+L+C   G P P+VTWY+DGK   K+     
Sbjct: 27583 MTKDESVI--PQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDIT 27640

Query: 1528  TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
             T                   Y   A N  G  +   +V +Q  P      E   +   + 
Sbjct: 27641 TVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQDTPG---PPEGPLRFTNIS 27697

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN------ITTKEKTSVIRIKELKRSHSS 1641
              E    A +   PP         N +   +E +      +T+K +       +L + +  
Sbjct: 27698 AE---KATLWWSPPENDGCAAISNYVIEKRETSRISWALVTSKCEACSFNATKLIKGNEY 27754

Query: 1642  KYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
             ++ + A N  G      S   +    Y  P  P  P     ++  S+T+ W  P  DGG 
Sbjct: 27755 QFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTPDCTH-VTGNSITLCWTRPRHDGGN 27813

Query: 1697  ELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE- 1754
             E+ +Y +E+ E  + RW+KV+      E  + +  L E  EY FRV+A+N  G   A   
Sbjct: 27814 EIKQYILERREKKSLRWVKVSAKRPITELRHRVTNLTEGNEYEFRVMAENGAGIGPASGI 27873

Query: 1755  SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813
             S     +     PS              SV + W     +GG  II Y +E+ K   ++W
Sbjct: 27874 SRLFKCREPTSAPSAPTLVKVIDSTKT-SVTLAWTKPVFDGGLEIIGYIIEMCKASLEEW 27932

Query: 1814  KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
                          R+ +L     Y+FR+ A N  G    ++    I          Q  +
Sbjct: 27933 HRVNNQTCIQTHYRVTELESGEEYKFRVCAVNGAGKG-EFSETPHIV---------QAVD 27982

Query: 1872  FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI---------VTVGGSV 1922
              + S         K T    NGG+   +     K V   +WTK          +    + 
Sbjct: 27983 RLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTF 28042

Query: 1923  HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
                 IEN    D   + +S EN  G    T +  V        P PP  PL  + V    
Sbjct: 28043 STLTIENCTRYDAGKYTLSLENNSGRKTITLTVKV-----LDTPGPP-GPLSFKDVTRGA 28096

Query: 1983  VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
             +   W  P  DGGA +  Y +  R+ ++  W EV +     +   + +L     Y  R+ 
Sbjct: 28097 LTLMWDAPSNDGGARVHHYIVEKREASRLSWQEVSERCTRQI-LRVINLDIGVAYFFRVT 28155

Query: 2043  ARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDA 2101
             A N+ G  EP E  EP  +I      A EEP     +             W++ EH+  +
Sbjct: 28156 AENQYGKGEPYEMTEP--II------ATEEPASPKRLDVIDTTSTTASLVWMKPEHDGGS 28207

Query: 2102  DIRSY 2106
              I  Y
Sbjct: 28208 RITGY 28212



 Score =  169 bits (412), Expect = 5e-40
 Identities = 192/884 (21%), Positives = 354/884 (40%), Gaps = 80/884 (9%)

Query: 1226  DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283
             ++TW K +S++E  ++  L ++     + I++ T  D  +Y    ++   +++  + V V
Sbjct: 17607 EITWSKGESILERDKRTMLTNNFPVVQMRIKEATRADHGKYVLKAVNEAGEASATITVNV 17666

Query: 1284  VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH----TKPSID 1339
             ++ P    + +  Y  K     + +V + A P+ N    + + I++ C+     T   I 
Sbjct: 17667 LDRPGHCQNLKMTYVTKN----SCMVSWDA-PEDNGGSEITNYIVE-CREPSIRTWAMIS 17720

Query: 1340  SKSASLTIK-KVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKP---NILEI 1392
             S   +  +K K+      ++++  EN CG     + +  +  +D    PG+P   ++ +I
Sbjct: 17721 SDCTNRMVKAKLMENHEYLFRVSAENKCGPGPATETKTPILAIDPLQKPGEPENFHVGDI 17780

Query: 1393  DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450
               + + + W +P+  G S  + Y +E +  D   W  +    + +T   +     N  Y+
Sbjct: 17781 GKNFVFLKWRKPDYDGGSPNLGYYLERKAKDAEAWEKLHEGVLKETFFMVDKCVENHIYQ 17840

Query: 1451  FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVP 1509
             FR  + N+   S    T++   V+KE +IQ P ++ K +  I  +  E + L     G P
Sbjct: 17841 FRVQSTNDGGESAWVSTSDI--VVKE-EIQKPVLDMKFVGTIVVKAGESVRLEAGLRGKP 17897

Query: 1510  QPKVTWYRD---GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
             QP VTW +D   G   + +  T  +                Y   A N  G       V 
Sbjct: 17898 QPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVT 17957

Query: 1567  IQQ--KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
             +     PV  +    I    K    W       G      I  K   +      Y+ +  
Sbjct: 17958 VLDIPGPVRDMKISGISTD-KCRVAWDPPEDDGGCEVDSYIIEKCETRRMVWSTYSASLV 18016

Query: 1625  EKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKV-YDKPSKPEGPVIMREIS 1679
               T+   +  L   +   + + A N  GT     S  +  K  Y++P  P+ P + + I 
Sbjct: 18017 --TNYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPIIAKTQYNRPGPPDAPEVTK-IG 18073

Query: 1680  RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             ++ +T+ W PP +DGG  +T Y +E+ E    RW+ V           +  L  N +Y F
Sbjct: 18074 KDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPVTKSPISERRMKVTNLIPNHDYQF 18133

Query: 1740  RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
             RV A+N VG  E  + S PI  K  ++ P               S+ ++W     +GG+P
Sbjct: 18134 RVKAENEVGLGEPSKASRPITAKDPIEPPGPPGSLKVVDSTKT-SITLSWAKPVYDGGAP 18192

Query: 1799  IIDYKVEIK-------------QEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
             +I Y VE++             +EG KK             I  L     Y+FR+ A+N+
Sbjct: 18193 VIGYLVEMRDKVEMEGEQVRDPEEGWKKCNTSGQLVLTEYTISNLDERQEYEFRVSAQNQ 18252

Query: 1845  IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
             +G   P    D ++  +    P       +  S  + ++++        G PI      F
Sbjct: 18253 VGMGRPANVKDAVSPKEVHEHP----EIDLDASLRKGLSVR-------AGCPIR----LF 18297

Query: 1905  KTVKGKSWTKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVG-----VSLPTESQ 1955
              T++G+   K+    + V   +    ++ I     ++   S+    G     +S P+  +
Sbjct: 18298 ATIRGRPAPKVTWKRIGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSGEK 18357

Query: 1956  SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
             +V +         P   L+   +       +W  PE DGG+P+L Y +  R+V +  W  
Sbjct: 18358 AVFVRVKVLDTPGPVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRKTWTN 18417

Query: 2016  VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
                 D+    F I +L+    Y  R+ A N+ G+  P +S + +
Sbjct: 18418 CTN-DLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSY 18460



 Score =  169 bits (412), Expect = 5e-40
 Identities = 204/915 (22%), Positives = 353/915 (38%), Gaps = 58/915 (6%)

Query: 1192  EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKK------KSVIEDTEKFTL 1244
             E P       L + ++V +     + V I      +V WYK+      ++ I+ TE +TL
Sbjct: 20408 EVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTL 20467

Query: 1245  ISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
             +        +I +CT  D  +Y   L  +  K T  + V VV+ P   V+ +     K  
Sbjct: 20468 V--------VIPECTRYDAGKYVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHS 20519

Query: 1303  SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
               +   +           +I+  +   +  ++  + + +  S  I  +E      +++  
Sbjct: 20520 ITLQWEIPLIDGGSKIKNYIIEKREATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSA 20579

Query: 1363  ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
             EN  G    A+    +     PS P    + ++   +  + W +P++ G S I  YV+E 
Sbjct: 20580 ENEMGIGEPAETPDPIRASQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVIEA 20639

Query: 1420  QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
             Q  D+ +W  V  I         L  N+ Y FR +AVN    S  SE  E   V+ + + 
Sbjct: 20640 QLKDSDQWAHVTTIKALDYIATELVENAEYVFRIFAVNS---SGRSEPRESRPVVIKEQT 20696

Query: 1480  QSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXX 1535
              +P  +      K +  +  +++++     G P+P V W ++ ++LK T +   EN    
Sbjct: 20697 TAPEFDLRSIYQKTVVAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASS 20756

Query: 1536  X---XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ---KPVITISNEDIKQKHKVGDE 1589
                            Y     N  G V  +  V +      P   I  +++   + V   
Sbjct: 20757 TILNINEIKRKDGGQYSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDY-VLIS 20815

Query: 1590  WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
             W       G+P    I         +  E   T    T   +   L      ++ ++A N
Sbjct: 20816 WEAPENDGGVPINNYIVEMRETTGTSWMELAATVIRTT--FKAARLTTGIEYQFRVKAQN 20873

Query: 1650  TAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
               G     TS   V    +D P +P  P I+   +++++TI W  P  DGG  +  Y IE
Sbjct: 20874 RYGVGPYITSGPVVAAYPFDVPGQPGIPQIV-AFTKDAMTISWNEPSSDGGSPILGYHIE 20932

Query: 1705  KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
             + E ++  W +++        +    L +   Y FRVIA+N  G S+A  S+P  +  AL
Sbjct: 20933 RKEKNSILWQRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKA--SKPSEMTYAL 20990

Query: 1765  DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXX 1823
             D P           I    V + W   E +GG  I  Y VE ++    +W          
Sbjct: 20991 D-PVDPPSQPVALNITRHEVTLQWTKPEGDGGFSITGYTVEKRELPNGRWLKANFSNILE 21049

Query: 1824  AR--IQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                 +  L+ + +Y+FR+ ARN  G  S P    + I     +  P    +   S     
Sbjct: 21050 TNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVV 21109

Query: 1881  SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN--IKEKDEIIF 1938
                  +       G PI + I+  K  K    T  + +       C+ N     +D   +
Sbjct: 21110 KAGDIFKLDAHVTGRPIPS-IVWTKDGKELEDTAKMEIKTLDFYSCLINKDSLRRDGGAY 21168

Query: 1939  RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
              ++A N  G +    +  V L++    P PP  PL +  +     + SW  P  DGG  +
Sbjct: 21169 TLTASNPGGFAKFVFNVKV-LDR----PGPPEGPLHVTDMTVEKCVLSWLPPLHDGGGKI 21223

Query: 1999  LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               Y I  R+ ++  W  V   D+   ++ +  L + + Y+ R+ A N+ G+ EPLES+  
Sbjct: 21224 EYYIIQRRETSRLTWTNVA-TDLQVNRYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPA 21282

Query: 2059  FKVIPGEGSHADEEP 2073
                 P   S   + P
Sbjct: 21283 VATNPYVPSDPPQAP 21297



 Score =  167 bits (407), Expect = 2e-39
 Identities = 159/657 (24%), Positives = 286/657 (43%), Gaps = 38/657 (5%)

Query: 1137  VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
             ++W++ G E+  S   +++ DG+   L +   + +D G Y+C    E G  + +  L ++
Sbjct: 30197 IKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQ 30256

Query: 1193  -EPSINFTLRLPEFILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
               P  +    L E       T   L  V I      + W+  K  +  +E   + +    
Sbjct: 30257 AAPQFHPGFPLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESY 30316

Query: 1251  RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
               L+IR            V L  K  T   V  VE   K +  E    +      ++++ 
Sbjct: 30317 THLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLPEGPVVVDALLKSSVIIS 30376

Query: 1311  YQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVEN--TDAGIY-KLRLEN 1364
             ++  P+ +   ++ + I++K +  +     + S + S T  +V N    +G Y ++  +N
Sbjct: 30377 WKP-PKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQN 30435

Query: 1365  NCGHAD-VEM-NVTIL----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
               G ++ +E+ +V I+    +KP  P +P +  +   S  + W  P + G + I  Y +E
Sbjct: 30436 QYGISESLEIPSVVIIKSPFEKPGVPQRPFVSSVTKDSCVVSWKPPTSDGGAKIKNYFLE 30495

Query: 1419  YQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
              +E    +WI+V    I +T  + + L     Y FR    N    SD SE +E      +
Sbjct: 30496 KREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSD 30555

Query: 1477  TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE------ 1530
             T +++P  +  L+++  +   +        G P+P V WY++GK++    A  +      
Sbjct: 30556 TALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKG 30615

Query: 1531  NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV-G 1587
                              Y+  A N  G + TS  + ++   K  + +  + +   H + G
Sbjct: 30616 GYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRG 30675

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN--ITTKEKTSVIRIKELKRSHSSKYTI 1645
             +   +   I G P P V W K G ++ N+  Y+  I T+  TS++ +K ++R  S  Y I
Sbjct: 30676 EVVTIKIPISGKPDPVVTWQK-GQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734

Query: 1646  EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
              A N  G     V L V D P  P+  V + +I R+++T+ W P  +DGG E+  Y IEK
Sbjct: 30735 CAKNRFGMDKQTVELDVADVPDPPK-DVKVSDIGRDTLTLTWSPG-NDGGSEIINYIIEK 30792

Query: 1706  HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761
                  +RWI+VA        Y +  L    +Y FRVIA+N  G S+ +  ++P+  K
Sbjct: 30793 CPTTGDRWIRVAQTSE--SQYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDPVTTK 30847



 Score =  166 bits (404), Expect = 5e-39
 Identities = 167/760 (21%), Positives = 292/760 (38%), Gaps = 42/760 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284
             +TW+K  + ++  ++    ++     L +  C   D  +Y   L +    T   + V+V+
Sbjct: 14135 ITWHKDGNEMKADDRTFFRAEYTSCHLEVPSCLHADAGQYKVTLENRNGATSGTINVKVI 14194

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLV-DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
               P    D       K    V+    DY     P   +++  +   +  + K        
Sbjct: 14195 GLPGPCKDIVASEITKSSCKVSWEPPDYDG-GSPILHYVLQRREAGRRTYVKVMSGENKL 14253

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSI 1397
             S  +K +       +++R  N  G  + +E+   ++      +P PP         S S+
Sbjct: 14254 SWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPPVDVETHNPTSESV 14313

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
              + W  P   G S I+ Y++E        +    +  +     +++ L     Y+FR  A
Sbjct: 14314 TLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKGLTHEKQYQFRVRA 14373

Query: 1456  VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVT 1514
              N   +SD S +T   K    T      +   L++ +  +  E+I L     G P P++T
Sbjct: 14374 ENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKRGEEIRLDANISGFPYPQIT 14433

Query: 1515  WYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             W R+   +  +  K   E                  K  A  +  E +       ++K  
Sbjct: 14434 WMRNNATIWPEPLKKRPERPIKKKKEKEEKKEEGAEKKEADAEKKEEDKEAKEEDKEKK- 14492

Query: 1573  ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIR 1631
                  E+ K+K K          +E    PE  ++ + N+        I +K K  S I 
Sbjct: 14493 -EEKKEEEKEKEKE---------VEEPEEPEEEYHPSLNE-----RLTIESKRKGESYII 14537

Query: 1632  IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
             IK+  R     +TI+  N  GT+S    + + D P  P       EI + S+  +W PPL
Sbjct: 14538 IKDTIRGDHGVFTIKVENDHGTASASCEVNILDTPGPPVN-FKFEEIRKNSILCKWDPPL 14596

Query: 1692  DDGGLELTKYAIEKHEPDNNR--WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
             DDGG E+  Y +E+ +       WI V  + R  + + + KL E  EY+FRV A+N  G 
Sbjct: 14597 DDGGSEILNYILERKDNSKAELGWITVTSILRGCK-FLVPKLIEGKEYLFRVTAENKYGP 14655

Query: 1750  SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808
              +   ++P++ +   D P           +   S+ +TW     NG S I  Y VE ++ 
Sbjct: 14656 GKPCITKPVIARNPFDPPDAPEKPEIKD-VTASSMCVTWLEPNDNG-SAIEGYWVEKREI 14713

Query: 1809  EGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
                 W            I  + L    TY FR+ A N  G        +  T    + PP
Sbjct: 14714 NSTHWARVNRTMVPDLEINVEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKTAQAPIMPP 14773

Query: 1867  SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
               P   +V +++  S+ ++W  P  NGG+ +  Y ++      K W++            
Sbjct: 14774 GPPIPRIV-DTSDYSIDIEWDPPADNGGAEVFGYHVDKLVAGTKDWSRATERPHKTRTFT 14832

Query: 1927  IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
             +  ++E  + I R+ A N  G   P  + +V +   A VP
Sbjct: 14833 VYGVREGAKYIVRVVAINCAGEGEPGLTDAVIVRNPAEVP 14872



 Score =  166 bits (404), Expect = 5e-39
 Identities = 208/959 (21%), Positives = 363/959 (37%), Gaps = 66/959 (6%)

Query: 1138  RWFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
             +W++   +   S    +T     KK   ++   +    GE+S   G+ +      VE P 
Sbjct: 29020 QWYRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMGTGEFS--EGSMETAPSERVEIPD 29077

Query: 1196  INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LI 1254
             I     L + + + A     L V +      V  ++K  +  D +    I   +  T LI
Sbjct: 29078 IELPDELKKTVCIRAGNTLRLNVTVSGRPAPVITWRKTGI--DLQSRGFIDTTENSTSLI 29135

Query: 1255  IRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
             + K    D  +YT    +   K T  + V++ + P        +   K    +T  V   
Sbjct: 29136 VEKVHRYDAGKYTIEAENPSGKKTITILVKIYDTPGPCGAVNVKDYTKESVVITWDVPTI 29195

Query: 1313  AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG---HA 1369
                   + +I+  +      +   + + K     I  +E      +++  EN  G     
Sbjct: 29196 DGGAHINNYIIEKREASMKSYKTVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPC 29255

Query: 1370  DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
             +    V + + PS P    +++   S++ + W++P + G S +  +V+E  +  T  W++
Sbjct: 29256 ETPEPVLVCEVPSVPQDLYLIDTTKSTVILGWEKPLHDGGSRLSGFVIEACKTGTDRWMN 29315

Query: 1430  VKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK- 1486
             V ++  +  Q +I +L  N  Y FR  A N   +S+  +      + ++ ++    +   
Sbjct: 29316 VAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKIDLTGI 29375

Query: 1487  PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXXXXXXX 1541
             P K +     + I L     G P P  +W   G K+K         T             
Sbjct: 29376 PQKIVNVPAGKPIVLNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETT 29435

Query: 1542  XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                   Y     N  G       V I  KP + +    I++     D   VT   E   P
Sbjct: 29436 IDDTGDYTLNVKNVSGTATEVIRVIILDKPGVPVGPMKIEEV----DATSVTCSWE---P 29488

Query: 1602  PEVIWYKN--GNKLENDKEYN---ITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGT- 1653
             P+     N  G  +E    +    ++  E  +  V +   L       + + A+N  G  
Sbjct: 29489 PQKDGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGTEYVFRVAATNRFGIG 29548

Query: 1654  ----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
                 S V     V   P  P  P I+ ++S + +T+ W PP D+GG  +  Y IE+ E  
Sbjct: 29549 GFLQSEVVECKSVKTVPGAPSTPEIL-DVSHDGMTLTWTPPEDNGGSTIAGYIIERKEAG 29607

Query: 1710  NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768
             ++RW+ +      +  Y    L E  EY +RV A N  G  + +  S+P +    ++ P 
Sbjct: 29608 SDRWLSINKNPVTMTRYRATGLIEGLEYEYRVTAINSRGTGKPSANSKPTIAMDPIEPPG 29667

Query: 1769  XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXAR-- 1825
                           SV + W P E+ GG+ +  Y +E+ K +  +W              
Sbjct: 29668 IPLNPRVTDTT-RTSVSLAWSPPEEEGGAAVTGYLIEMQKVDQVEWTKCNTTPTKICEYT 29726

Query: 1826  IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
             +  +     Y+FR+ A N  G   P      + + + L  P      +  E         
Sbjct: 29727 LTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEKIYQEGYV------ 29780

Query: 1886  WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-HEHCIENIKEKDEIIFRISAEN 1944
                    GG    +  I+ K +    WTK    G  + H   I   +E+ E++ + +  +
Sbjct: 29781 ----VRQGGVIRLSVPIKGKPLPTCKWTK---EGRDISHRAMIATSEERTELVIKEAHRD 29833

Query: 1945  TVGV-SLPTESQSVRLEKHATV-----PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
               G   L  E++  R   +  V     P PP  PLE   + +  V  SW  P  DGG+ +
Sbjct: 29834 DTGTYDLVLENKCGRKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGSDI 29893

Query: 1999  LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              GY +  R+V K  W  V    V+T    ++ L EN  Y  +I A N+ G+S+ L+SDE
Sbjct: 29894 FGYIVERREVPKAAWYTVDSRVVDT-SLVVKGLKENVEYHFKITAENQFGISKSLKSDE 29951



 Score =  165 bits (400), Expect = 2e-38
 Identities = 184/716 (25%), Positives = 297/716 (41%), Gaps = 61/716 (8%)

Query: 1379  DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436
             D P  P KP I ++ +SS+ + W EP + G S I  Y VE +EI++T W  V    +   
Sbjct: 14671 DPPDAPEKPEIKDVTASSMCVTWLEPNDNG-SAIEGYWVEKREINSTHWARVNRTMVPDL 14729

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             + +++ L    +Y FR  A N       S  +E      +  I  P    P    T++ +
Sbjct: 14730 EINVEGLLEGLTYIFRVCAENIAGPGKFSPPSE--PKTAQAPIMPPGPPIPRIVDTSDYS 14787

Query: 1497  EDIELT--CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXY-- 1548
              DIE       GG    +V  Y   K +   K    AT                   Y  
Sbjct: 14788 IDIEWDPPADNGGA---EVFGYHVDKLVAGTKDWSRATERPHKTRTFTVYGVREGAKYIV 14844

Query: 1549  KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPP 1601
             + +A N  GE E   T  V+ ++    + +   DI  ++ V    G+   + A + G PP
Sbjct: 14845 RVVAINCAGEGEPGLTDAVI-VRNPAEVPVIELDISVRNGVVVRAGEMLRIPAHVTGRPP 14903

Query: 1602  PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
             P + W K+   LE D+   +    + S + IK  KRS   KY I+A+N +G  S    ++
Sbjct: 14904 PSLKWTKDDGDLEKDR-MEVEEAGQDSTVVIKTTKRSDHGKYQIQAANPSGIKSAWTRVE 14962

Query: 1662  VYDKPSKPEGPVIMRE---ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             V D P    GPV+  +   ++R+ + + W  P DDGG ++T + IE+ EP  + W +   
Sbjct: 14963 VMDVP----GPVLDLKPVVVTRKLMMLNWSDPDDDGGSDVTGFIIERREPKMHTWRQ--P 15016

Query: 1719  VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXX 1776
             ++       I  + E  EY+FRV+A+N  G    ++  PI    A+D   P         
Sbjct: 15017 IETPSSKCEIVGIIEGQEYIFRVVAKNKYGCGPPVDLGPI---RAVDPQGPPTSPEKFHY 15073

Query: 1777  XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI---QKLSINT 1833
                   SV I W P   +GGSPII Y +E K++ +             +I     L    
Sbjct: 15074 TERTKSSVTIEWRPPRNDGGSPIIGYIIEKKRQDQPAFQRVNPELCTVQIMTVDNLDELH 15133

Query: 1834  TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
              Y+FR  A N  G S P  +   +     + P  +       +            P    
Sbjct: 15134 MYEFRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVT 15193

Query: 1894  GSPI-------TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946
             G P+        + +IE  T K    TK +    S  +  I  +   D+  + ++A N +
Sbjct: 15194 GLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDKGTYTVTASNRL 15253

Query: 1947  GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
             G    T S SV +E     P+PP   + +  + +     SW  P   GG+ L  Y + ++
Sbjct: 15254 G----TLSHSVTVEV-LDRPTPP-RNVAVSSIKAESCNLSWDAPLDIGGSELTNYIVEMK 15307

Query: 2007  DVT-----KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             D+      K  W++V K  +   ++ + +L     Y  R+ A N+ G+SE  E++E
Sbjct: 15308 DLNVEDPEKAEWVQVTK-SIIEKRYGVWNLVTGGNYKFRVKAENKYGISEACETEE 15362



 Score =  163 bits (397), Expect = 4e-38
 Identities = 132/460 (28%), Positives = 212/460 (46%), Gaps = 30/460 (6%)

Query: 1621  ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMR- 1676
             +T   + S I I ++  +    + ++A N AG    S+    +K+ D   +P  P+ +  
Sbjct: 12957 VTKPHERSAI-INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMDPIERPSPPLNLTH 13015

Query: 1677  -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNEN 1734
              E +++S  + W+ PL +GG  +T Y IE+ E   ++W++  A +  D+  Y +  L   
Sbjct: 13016 SEQTKDSCLLTWETPLKNGGTAITGYIIERCEEGTDKWLRCNARLCPDL-LYRMSGLKFG 13074

Query: 1735  CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
              +Y +RVIA+N  G S+      IV     D P            D   V++   P+  +
Sbjct: 13075 KKYSYRVIAENAAGQSDPSN---IVGPVLADDPHYAPTLDLSAFKDGLEVFV---PNPLS 13128

Query: 1795  GGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY--ARNEIGT-SLPY 1851
                PI  Y +       KW           R+  ++ +T  +  I    R + GT SL  
Sbjct: 13129 IRVPITGYPIPTA----KWTFGENALTAGDRVSMVTKSTFTELVITPSVRADKGTYSLTL 13184

Query: 1852  TSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
              +D     G+     +  PS P++  V+E T + V L W  PE +GGSPIT Y +E + V
Sbjct: 13185 ENDVASVSGEIEVNVIASPSAPKDLKVAEVTRKHVHLMWEAPEHDGGSPITGYQVEKREV 13244

Query: 1908  KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVP 1966
               K+W K+++ G    E+ + ++ E  E +FR+ A N  G   P   +  V +   ATVP
Sbjct: 13245 SRKTWVKVMS-GLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPAYIEDPVNVSSPATVP 13303

Query: 1967  SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
              PP   L+ R   ++ +  SW  P+WDGG P+ GY +         W   G   +  LKF
Sbjct: 13304 DPP-ENLKWRDKSASKIFLSWEPPKWDGGTPIKGYIVDKCQRGTDKWEPCGD-PMPELKF 13361

Query: 2027  NIRDLSENHTYMIRIYARNEIGLSEPLES-DEPFKVIPGE 2065
              +  L E   Y  R+ A N++G S+P +S DE   V P E
Sbjct: 13362 EVTGLIEGQWYAYRVRALNKLGASKPCKSTDEILAVDPKE 13401



 Score =  163 bits (397), Expect = 4e-38
 Identities = 127/468 (27%), Positives = 204/468 (43%), Gaps = 18/468 (3%)

Query: 1594  AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             A I G P P+V W + G  ++N  +  ++   +  + + I E  R  S KY++  SN +G
Sbjct: 18298 ATIRGRPAPKVTWKRIG--VDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSG 18355

Query: 1653  TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
               +V V +KV D P  P G +   +I++ S  + W PP +DGG  +  Y +EK E D   
Sbjct: 18356 EKAVFVRVKVLDTPG-PVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRKT 18414

Query: 1713  WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772
             W    + D    ++ I  L    EY FRV+A N  G     +S    + T          
Sbjct: 18415 WTNCTN-DLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATDPKSEPDPPK 18473

Query: 1773  XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829
                   I   S  + W    ++GGS I  Y VE +Q+G+   KW            +  L
Sbjct: 18474 KMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQDGQPEDKWTSYSVVKDLTIVVAGL 18533

Query: 1830  SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
               NT Y+FR+ ARN IG SL   ++    + + L  P    + VV+      + +     
Sbjct: 18534 KENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIVSDVVTARAGSKLIVDALV- 18592

Query: 1890  ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
              S   +P+T +      +   S   ++    +     ++++  KD   + +SAEN    S
Sbjct: 18593 -SGKPAPVTKWKRGSDDIV-TSDRVVIQKTPTTSLLMVKDVTRKDSGYYSLSAEN----S 18646

Query: 1950  LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
                 +Q +R+     +P PP  PL+I  V  +    +W TP  DGG+ +  Y +   DVT
Sbjct: 18647 TAKVNQIIRIII-MDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSNITNYIVEKCDVT 18705

Query: 2010  KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             +  W  V  V        +  L+    Y  R+ A N  G+SEP+ S++
Sbjct: 18706 RGDW--VTAVSCTKTSCRVGKLTCGKEYGFRVRAENRFGISEPIYSEK 18751



 Score =  163 bits (396), Expect = 5e-38
 Identities = 172/767 (22%), Positives = 300/767 (39%), Gaps = 50/767 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP FS+K K      G  + L+C+        I+W     EI+   N  +    +    
Sbjct: 6842 VPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTENT--- 6898

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            C+ LK+  +K    GTY   AVN  G A     L +K    EPP  +   + +    G +
Sbjct: 6899 CT-LKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVK----EPPSFVTTPQPVEALPGTT 6953

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V  +A V G+    + W + +K +   ++      GDT  + +    K    G YT +  
Sbjct: 6954 VTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAILELHNIDK-SHAGEYTCQII 7012

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G       + V+E          F+ + + ++V+   ++ L      +P   + W++
Sbjct: 7013 NDAGKENCPVNLFVKEAAH-------FVKKLKNLSVEMGKSLILECTYAGSPKILVKWHK 7065

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            + + I  S          +  L   N D E  +G Y C  SN AG     A V+I +E  
Sbjct: 7066 DGQEIYSSYKYNITTTESSCILECLNSDKEA-AGKYTCEVSNDAGHDICEAAVSI-LEPP 7123

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXX 986
             F++ L+   E   G  V L+CQ   T   K  W+    ++      ++           
Sbjct: 7124 FFIESLEPM-EVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEFFKGIACLKL 7182

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040
                  D+G   C  ++      +S  L V++  T P F +K+      E      E  +
Sbjct: 7183 AKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSIMQIEGQPVQFECRV 7242

Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
              S   +V W +DGE ++   ++Y      +   L I    +   GEY+C+  +     S
Sbjct: 7243 AGSSPMEVSWLKDGEALR-SDSEYTMSFDDNSAVLNIAKGEMRHSGEYTCVATNSVGSAS 7301

Query: 1096 CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152
            C A++T+ E   PP    +L    V+ G+    E  +T    + V W KD  +I+   + 
Sbjct: 7302 CRAKLTLQEPRYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNY 7361

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
            +++       L I   D  D+G YSC    +VG   C+  ++V+E  I  +        +
Sbjct: 7362 KISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPPSFTKKPSTTI 7421

Query: 1209 PANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
                   + +E      + L V WYK    I  ++ + +        L I+K    D   
Sbjct: 7422 EDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGT 7481

Query: 1266 YTCVLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            Y C   +   T   +V V     + PP      +   +  G  +TL    +  P    +W
Sbjct: 7482 YVCKATNEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQW 7541

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
            + + + +    +TK +    +A+L + +V  TD+G Y  +  N  G+
Sbjct: 7542 MKDRRELSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKATNEAGN 7588



 Score =  161 bits (390), Expect = 3e-37
 Identities = 124/428 (28%), Positives = 191/428 (44%), Gaps = 18/428 (4%)

Query: 1642  KYTIEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
             ++ + A N AG S      E+T  + D    P  PV +  I+R  VT++W  P  DGG  
Sbjct: 20966 EFRVIAENLAGLSKASKPSEMTYAL-DPVDPPSQPVALN-ITRHEVTLQWTKPEGDGGFS 21023

Query: 1698  LTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGF--SEALE 1754
             +T Y +EK E  N RW+K A+    +ET + +  L E+  Y FRV+A+N  G     +  
Sbjct: 21024 ITGYTVEKRELPNGRWLK-ANFSNILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKP 21082

Query: 1755  SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK 1814
             SE IV +  ++ P           +  ++  I    +   G  PI    +   ++GK+ +
Sbjct: 21083 SEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTG-RPIPS--IVWTKDGKELE 21139

Query: 1815  XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV- 1873
                             IN     R      +  S P      +   K L  P  P   + 
Sbjct: 21140 DTAKMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGGFAKFVFNVKVLDRPGPPEGPLH 21199

Query: 1874  VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
             V++ T     L W  P  +GG  I  YII+ +     +WT + T    V+ + +  + + 
Sbjct: 21200 VTDMTVEKCVLSWLPPLHDGGGKIEYYIIQRRETSRLTWTNVAT-DLQVNRYKVTKLLKG 21258

Query: 1934  DEIIFRISAENTVGVSLPTESQSVRLEKHATVPS-PPTAPLEIRMVGSNIVMTSWGTPEW 1992
             +E IFR+ A N  GV  P ES+   +  +  VPS PP AP E+  +  + ++  WG PE+
Sbjct: 21259 NEYIFRVMAVNKYGVGEPLESEPA-VATNPYVPSDPPQAP-EVTAITKDSMVVCWGHPEY 21316

Query: 1993  DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             +GG+ +  Y I  RD T   W++  K  V  L+F +  L+  H Y  RI A N  GLS P
Sbjct: 21317 NGGSSINTYIIERRDKTGLRWVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAP 21376

Query: 2053  LESDEPFK 2060
               S   +K
Sbjct: 21377 SPSSPFYK 21384



 Score =  159 bits (387), Expect = 6e-37
 Identities = 233/1100 (21%), Positives = 439/1100 (39%), Gaps = 81/1100 (7%)

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
            W+  G  I   + + + I+  +H     L + NV K   G Y+ V   ++   S  + + 
Sbjct: 2161 WMKNGLPISASDRVHIVIDKLVHK----LLVENVNKDDAGIYSFVVPIQDISTSGKLTV- 2215

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783
                  +  ++I  LK +   +G   +L A++  +    + W +N+K + A   +   + 
Sbjct: 2216 ------QSIEIISHLKDVHSIEGTKAVLEAKISASDVAAVKWYQNDKLLVASERIQMVAK 2269

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
            G T    +L      DEG Y +      G  ET+  +TVE+ +         I   ++  
Sbjct: 2270 G-TKQRLVLNRSFGSDEGQYKMAV----GRVETTCNLTVEKVS--------IIKHMEDCV 2316

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
              E   +     ++   + +  W   N+ +           G++  L I N   + + G 
Sbjct: 2317 CTETQNVTFEVELSHTGIDAY-WTFKNQPLKAGPKYKIESKGKHYSLTIINAMKD-EEGL 2374

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYH 962
            Y    + +AG+    A++T+    +    H        E +T ++EC+ ++  S  KW  
Sbjct: 2375 Y----AFAAGEKISSAKLTVSGGAINRPLH---DVTVAESQTAVMECEVANPTSEGKWLK 2427

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK 1022
            +   +   D                     D+G     V + +TS  L V+    +  + 
Sbjct: 2428 DGHSVDFSDIVRSEDIDAVRRLIFVITRPQDIGEYTYQVANSKTSANLRVEAV--KIKKT 2485

Query: 1023 LQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
            L++  V E   A+  +E+   +     W ++G  I+P  +KY+    G +  L I+N + 
Sbjct: 2486 LKNQTVTETQEAVFSLELTHLDVKGSQWIKNGVEIEPS-DKYEITVDGLVHTLKIKNCNS 2544

Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141
             DE  Y   L   S  A + V  +  +I+ + ++        A+FE+ L+  D  V+W  
Sbjct: 2545 QDESVYGFKLGKLSANARLNVETI--KIVKKPKDVTSLVNGTASFELSLSHDDIPVKWMF 2602

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201
               E++ S ++Q+  + K  KL I + +  + GEY+  VG+ +C+A L VE   +   L+
Sbjct: 2603 KNQELKPSANVQIMSERKAHKLVIQNVEESNDGEYTAVVGHLQCSAYLHVESLRVTKPLK 2662

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
              E   VP    A    E+    +  TW K    IE +EKF ++   K   L I   + D
Sbjct: 2663 NLE---VPETHVATFECEVSHFNVPSTWLKNGVEIEMSEKFRIVVQGKLHQLKIMNTSRD 2719

Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            D  EYT V  + K +  L V  V     + D   + +     +VT  V+Y+       +W
Sbjct: 2720 DSAEYTFVCGNDKVSATLTVSPVLITSMLKDLNAQEKDTITFEVT--VNYEGITY---KW 2774

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
            + N   I+     +      S SLTI+ V   D G YK       G A+    + +  + 
Sbjct: 2775 LKNGVEIRSSDRCQTRTKQLSHSLTIRNVHFGDVGDYKFV----AGSAETAAKLFVEARV 2830

Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSI 1440
                K +I +I  +       E E +  +  + ++ + QE++ +E   V       +  I
Sbjct: 2831 IEFTK-HIKDIKVTEKKKAVFECELSEPNVQVTWMKDGQELELSERYKVSTERHVHRLMI 2889

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED-I 1499
            Q ++ + +  +   A + V  ++ +   +  ++ +  + +   +EK       E NED I
Sbjct: 2890 QTVRMSDAGEYSVVAGSSVSKANLTVEGKDVRISEPAEKEITVLEKQRSTFEFEVNEDDI 2949

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
            E   +  GV   ++ +  D ++   A     +R               Y  IA  +   V
Sbjct: 2950 EGRWLRNGV---EIQFSVD-QRFNYAIIRKIHRLTITETYRSDAGE--YTFIAGKNRSIV 3003

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                 V I + P I    + +  +   G     +  + GIP P+V WYKN   L +  + 
Sbjct: 3004 TLH--VNIPEPPQIIRHMQPLSVE--AGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKC 3059

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEG-----P 1672
                +     + + E+    +++Y  EA N  G  TSS  + ++V +  S   G     P
Sbjct: 3060 KFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPP 3119

Query: 1673 VIMREI----SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            V++  I    + E  +  ++  +    L +T Y  +K E   +   +V+  D + +   I
Sbjct: 3120 VVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDK-EIKQSDIFRVSQFDENCQLE-I 3177

Query: 1729 QKLNENCEYMFRVIAQNPVG 1748
             ++    E  +  +A+N  G
Sbjct: 3178 TRVYPEDEGEYTCVARNSAG 3197



 Score =  155 bits (376), Expect = 1e-35
 Identities = 182/801 (22%), Positives = 313/801 (39%), Gaps = 76/801 (9%)

Query: 1349  KVENTDAGI---YKLRLENNCGHADVEMN---VTILDKPSPPGKPNILEIDSSSINICWD 1402
             KV N +AG+   +K+  EN  G   +  +   V  +D   PP    + +I  +SI++ W 
Sbjct: 26365 KVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPNSVRVTDITKNSISLAWQ 26424

Query: 1403  EPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV- 1459
             +P   G S I  Y++E ++     W   ++ N+T T+ ++  L  N SY FR  A N V 
Sbjct: 26425 KPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRVMAKNAVG 26484

Query: 1460  DISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
              +S+ SE       +      +P V+ P   L  +  +    ++L       PQP + WY
Sbjct: 26485 SVSNPSEIVGPVTCVDT--YGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIEWY 26542

Query: 1517  RDGKKLKT-AKATYENRXXXXXXXXXXXX---XXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             +DGK+L++ A+ +  N                   Y+    N  G    +  V +Q KP 
Sbjct: 26543 KDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYAAVRVLVQDKPG 26602

Query: 1573  ITISNEDIKQKHKVGDEWLVTAVIEGIPPPE----VIWYKNGNKLENDKEY--NITTKEK 1626
                   +I+ K    D    T  I   PP +    ++ +    K E  +     I+ K +
Sbjct: 26603 PPAG--EIQFKKITAD----TMTIMWDPPADEGGAMVTHYIVEKRETSRIMWSIISEKLQ 26656

Query: 1627  TSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRE 1681
               ++ +  L + +   + +   N  G      S   +    +  PS+P  P +   I+R 
Sbjct: 26657 DCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRPVIAQNSFVHPSQPSKPQVTM-ITRS 26715

Query: 1682  SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFR 1740
             ++T+ W+ P  DGG ++  Y +EK E  + +W KV  D  RD     +  L E  EY +R
Sbjct: 26716 TMTVVWERPSLDGGSDIDGYYLEKREKKSLQWFKVIKDPIRDTRQK-VHNLTEGNEYQYR 26774

Query: 1741  VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT--WFPSEKNGGSP 1798
             V A N  G      S+  +   A D             +D+    IT  W     +GGS 
Sbjct: 26775 VCAINKAGAGPY--SDVSIFYKAYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSE 26832

Query: 1799  IIDYKVEIK-QEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
             I  Y +E +  +  +W               +  L     Y +R+ A N +GT       
Sbjct: 26833 ITSYVIEQRIADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIE-- 26890

Query: 1855  DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI-IEFKTVKGKSWT 1913
                     +  P Q ++ +        +++  T+  +  G  +   I ++ +     +W 
Sbjct: 26891 --------IVQPVQAKDILEEADVDLDISMS-TQYIAKAGRDVEIVIPLKGRPAPNVTWR 26941

Query: 1914  K-IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP----SP 1968
             K    + G    + I N +    +I      +  G  L      V   K  TV       
Sbjct: 26942 KGDKNISGDAR-YAIRNTEYSTTLIIPKVTRDDTGKYLLEIENGVGEPKTITVSVKVLDT 27000

Query: 1969  PTA--PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
             P+A   L ++ V    +  SW  P  DGG+P+  Y +  +D     +  V     NT  +
Sbjct: 27001 PSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITNYVVEKKDAKMKAFTIVTNECANTT-Y 27059

Query: 2027  NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXX 2086
              +  LSE  +Y  R+ A NE G+ +P E+++P +        A E PG   ++       
Sbjct: 27060 KVDGLSEEISYFFRVSAENEYGVGDPCETEQPVR--------ATEMPGAIKDLVLVDSTN 27111

Query: 2087  XXXXXXWLR-EHNMDADIRSY 2106
                   W + +H+  + I  Y
Sbjct: 27112 TSVSLAWTKPDHDGGSHINEY 27132



 Score =  153 bits (370), Expect = 7e-35
 Identities = 122/474 (25%), Positives = 197/474 (41%), Gaps = 22/474 (4%)

Query: 1642  KYTIEASNTAGTSSVEVTLK--VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             ++ + A N  G      T +  +   P  P G  +   ++R SV + W PP  DGG  +T
Sbjct: 23129 EFRVYAENIVGIGKCSKTSEGCIARDPCDPPGTPVPVIVTRHSVKLRWTPPEYDGGSLVT 23188

Query: 1700  KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
              Y +EK +    RW+K +  +     + +  L E+C+Y FRVIA+N  G S +  SE   
Sbjct: 23189 GYVVEKRDLPEGRWMKASFANILETEFTVTGLIEDCKYDFRVIARNGAG-SVSRPSESTG 23247

Query: 1760  IKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID---YKVEIKQEGKKWK 1814
               TA D   P           I   +   T+       G PI     +K +++ E     
Sbjct: 23248 SVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARA 23307

Query: 1815  XXXXXXXXXARIQKLSINTTY-QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                        + K +I     Q+ ++  N  G+    +    + +     PP  P    
Sbjct: 23308 EIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSK---SVSFNVRVLDRPGPPEGP--LT 23362

Query: 1874  VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
             VS  T+   +L W  P  +GGS I+ Y+I+ +     +WT +V+         +  + + 
Sbjct: 23363 VSGVTNEKCSLSWLPPRHDGGSSISYYVIQKRETSRLAWT-VVSGDCGATMFKVTKLLKG 23421

Query: 1934  DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
             +E IFR+ A N  GV  P ES++V +      P PP   LEI  +  + +   W  PE D
Sbjct: 23422 NEYIFRVMAVNKYGVGEPLESRAVIMRNPFVAPGPPQ-DLEITNISRDSMTVCWTRPESD 23480

Query: 1994  GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
             GG  ++GY +  RD     W +  K  V  L+F +  L+E+H Y  R+ A N  G+ +P 
Sbjct: 23481 GGNEIVGYIVEKRDRAGIRWTKCNKRRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPS 23540

Query: 2054  ESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLRE-HNMDADIRSY 2106
             +    +K           +PG+ T               W R  ++   DI+ Y
Sbjct: 23541 QPTVYYK-----ACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGY 23589



 Score =  152 bits (368), Expect = 1e-34
 Identities = 151/691 (21%), Positives = 288/691 (41%), Gaps = 29/691 (4%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-E 889
            E P  + R Q  TV     ++   RV   P P   W++N  ++  S+ +   +  +++ E
Sbjct: 1849 EAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPEDHVCE 1908

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVIL 948
            LVI +V +E DS      A N AG++S  A + +  ++V +F + L+ +Y  E+   V  
Sbjct: 1909 LVIRDVLAE-DSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKEKDTMVTF 1967

Query: 949  ECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-- 1005
            EC+T+   V  KW  N  EI   D   +  + +            D     C V D +  
Sbjct: 1968 ECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQDDAEYSCAVVDDDHI 2027

Query: 1006 -TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064
             T+  L V+    E ++ L+  EV E      E E++ E A+  W  + + I P   KY 
Sbjct: 2028 RTTARLYVEGAPLEIVKNLESVEVPETYSGEFECELSREDAEGTWYFENKEITPSL-KYV 2086

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
               R     L +++    D+G+Y+  + D   +A + +   P  ++  L +  + +G+ A
Sbjct: 2087 VSSRRGRHTLSVKDVRKEDQGKYTFKVGDLKTSATLKMKLRPVTLMQGLSDLTICEGDIA 2146

Query: 1125 TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
              E+  ++ +    W K+G  I  S+ + + ID    KL + + + DDAG YS  V    
Sbjct: 2147 QLEVRFSQENVEGTWMKNGLPISASDRVHIVIDKLVHKLLVENVNKDDAGIYSFVVPIQD 2206

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFT 1243
             +    +   SI     L +   +   T A L  +I   +   V WY+   ++  +E+  
Sbjct: 2207 ISTSGKLTVQSIEIISHLKDVHSI-EGTKAVLEAKISASDVAAVKWYQNDKLLVASERIQ 2265

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
            +++   K+ L++ +    D+ +Y   +   ++T  L VE V     I+ +  +       
Sbjct: 2266 MVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKV----SIIKHMEDCVCTETQ 2321

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            +VT  V+  +    +  W   ++ +K     K     K  SLTI      + G+Y     
Sbjct: 2322 NVTFEVEL-SHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINAMKDEEGLYAFAAG 2380

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
                 A + ++   +++P       + E  ++ +      P + G      + V++ +I 
Sbjct: 2381 EKISSAKLTVSGGAINRPL--HDVTVAESQTAVMECEVANPTSEGKWLKDGHSVDFSDIV 2438

Query: 1424 TTEWISVKN-----ITKTQT------SIQNLKTNSSYRFRAYAVNE-VDISDASETTEYY 1471
             +E I         IT+ Q        + N KT+++ R  A  + + +     +ET E  
Sbjct: 2439 RSEDIDAVRRLIFVITRPQDIGEYTYQVANSKTSANLRVEAVKIKKTLKNQTVTETQEAV 2498

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
              ++ T +     +     +  EP++  E+T
Sbjct: 2499 FSLELTHLDVKGSQWIKNGVEIEPSDKYEIT 2529



 Score =  151 bits (365), Expect = 3e-34
 Identities = 122/484 (25%), Positives = 203/484 (41%), Gaps = 18/484 (3%)

Query: 1596  IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             ++G P PE+ W +   +  +     IT    T  + I+ + R    KY +   N++GT +
Sbjct: 21520 VKGRPAPEIRWSREKGEPLDRASIEITPSFTT--LLIENVDRFDGGKYMLTVENSSGTKT 21577

Query: 1656  VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
               + ++V D P  P+   I +EI+++SV++ W PP+ DGG  +  Y +EK E     +  
Sbjct: 21578 AFINVRVLDTPGAPQNLTI-KEITKDSVSLIWDPPVIDGGSRIRHYIVEKRESTRKAY-S 21635

Query: 1716  VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
             + +      ++ I  L E   Y FR++A+N  G    +E+   +  +   +P        
Sbjct: 21636 IVNASCPKTSWRIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPP---GKVT 21692

Query: 1776  XXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTT 1834
                + + SV ++W   + +GGS I  Y VE++ +   KW          A +  L+    
Sbjct: 21693 LKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQGEE 21752

Query: 1835  YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
             Y FRI A NE G S P      +     +  P+    F  + S      LK   P     
Sbjct: 21753 YSFRISATNEKGISDPRPLSVPVIAKDVVIAPAFKLLF-STFSVLAGDDLKIDVPYV--A 21809

Query: 1895  SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI-IFRISAENTVGVSLPTE 1953
              P    + +   +  K  T++ T     H + +     +D++  + I   N+ G     +
Sbjct: 21810 QPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAG-EATAD 21868

Query: 1954  SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
                + L+K    P PPT P++I  V ++ V  SW  PE++GG  +  Y +  RD + T W
Sbjct: 21869 INVIVLDK----PGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINNYIVEKRDTSTTNW 21924

Query: 2014  MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
               V      T     R L     Y  RI A N  G S  + S+      P E  H    P
Sbjct: 21925 QIVSATVARTTTKAAR-LKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIP 21983

Query: 2074  GEQT 2077
               Q+
Sbjct: 21984 AVQS 21987



 Score =  149 bits (361), Expect = 8e-34
 Identities = 219/1096 (19%), Positives = 418/1096 (38%), Gaps = 86/1096 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P   ++ ++Q V    ++   CR++  P+P+  W   G  +   + +      D H+ C 
Sbjct: 1851 PKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPED-HV-CE 1908

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I +V      +  V A+N  GEAS    L ++   K+     + L+    ++ ++++
Sbjct: 1909 -LVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQA--KQVVSFTQTLEDAYAKEKDTMV 1965

Query: 754  LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
                    P   + W KNN  +         SD   H +++L    ++D+  Y+    + 
Sbjct: 1966 TFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVL-IINMQDDAEYSCAVVDD 2024

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            + I  T+ +     P E        +   + + V E  + +    ++R      TWY  N
Sbjct: 2025 DHIRTTARLYVEGAPLE-------IVKNLESVEVPETYSGEFECELSREDAEG-TWYFEN 2076

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            + I+PS     +       L + +V  E D G Y    +   G     A + + +  VT 
Sbjct: 2077 KEITPSLKYVVSSRRGRHTLSVKDVRKE-DQGKY----TFKVGDLKTSATLKMKLRPVTL 2131

Query: 931  VKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            ++ L       EG    LE + S   V   W  N   IS  D   I+ +           
Sbjct: 2132 MQGL-SDLTICEGDIAQLEVRFSQENVEGTWMKNGLPISASDRVHIVIDKLVHKLLVENV 2190

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVV 1048
               D G+   +V  Q+ ST   +     E I  L+D    E   A+LE +I+ S+ A V 
Sbjct: 2191 NKDDAGIYSFVVPIQDISTSGKLTVQSIEIISHLKDVHSIEGTKAVLEAKISASDVAAVK 2250

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W ++ +++   + +     +G  ++L +  +   DEG+Y   +     T  +TV ++   
Sbjct: 2251 WYQNDKLLVASE-RIQMVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKV--S 2307

Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            II  +++    +    TFE+EL+       W      ++     ++   GK   L I + 
Sbjct: 2308 IIKHMEDCVCTETQNVTFEVELSHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINA 2367

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228
              D+ G Y+   G    +A LTV   +IN  L     + V  +  A +  E+ + T +  
Sbjct: 2368 MKDEEGLYAFAAGEKISSAKLTVSGGAINRPL---HDVTVAESQTAVMECEVANPTSEGK 2424

Query: 1229 WYKKKSVIE--DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            W K    ++  D  +   I  V++   +I +    D  EYT  + ++K++  L+VE V  
Sbjct: 2425 WLKDGHSVDFSDIVRSEDIDAVRRLIFVITR--PQDIGEYTYQVANSKTSANLRVEAV-- 2480

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
              KI    +   +    +    ++         +WI N   I+     + ++D    +L 
Sbjct: 2481 --KIKKTLKNQTVTETQEAVFSLELTHLDVKGSQWIKNGVEIEPSDKYEITVDGLVHTLK 2538

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
            IK   + D  +Y  +L     +A + +  + I+ KP           D +S+        
Sbjct: 2539 IKNCNSQDESVYGFKLGKLSANARLNVETIKIVKKPK----------DVTSL-------- 2580

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
               N T  + +    +    +W+      K   ++Q +    +++     V E +  + +
Sbjct: 2581 --VNGTASFELSLSHDDIPVKWMFKNQELKPSANVQIMSERKAHKLVIQNVEESNDGEYT 2638

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
                + +      ++S  V KPLKN+           C       P  TW ++G +++ +
Sbjct: 2639 AVVGHLQCSAYLHVESLRVTKPLKNLEVPETHVATFECEVSHFNVPS-TWLKNGVEIEMS 2697

Query: 1526 K----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
            +                         Y  +  ND  +V  +  V      +IT   +D+ 
Sbjct: 2698 EKFRIVVQGKLHQLKIMNTSRDDSAEYTFVCGND--KVSATLTV---SPVLITSMLKDLN 2752

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
             + K    + VT   EGI      W KNG ++ +       TK+ +  + I+ +      
Sbjct: 2753 AQEKDTITFEVTVNYEGI---TYKWLKNGVEIRSSDRCQTRTKQLSHSLTIRNVHFGDVG 2809

Query: 1642 KYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             Y   A +    + + V  +V +        K ++ +  V   E+S  +V + W    D 
Sbjct: 2810 DYKFVAGSAETAAKLFVEARVIEFTKHIKDIKVTEKKKAVFECELSEPNVQVTWMK--DG 2867

Query: 1694 GGLELT---KYAIEKH 1706
              LEL+   K + E+H
Sbjct: 2868 QELELSERYKVSTERH 2883



 Score =  149 bits (361), Expect = 8e-34
 Identities = 162/713 (22%), Positives = 280/713 (39%), Gaps = 45/713 (6%)

Query: 1374  NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-- 1431
             ++  LD   PPGKP+++ +  +S+ + W  P+  G   +  Y+VE  E     W+     
Sbjct: 19903 SLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMKANHV 19962

Query: 1432  NITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
             N+     ++ +L+   +  FR  A N    IS  SETTE      E +  + T++  +K+
Sbjct: 19963 NVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEMKD 20022

Query: 1491  -ITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544
              +T +    I +T     G P P   W + G++ K++     ++                
Sbjct: 20023 GVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPTSSTLSIKYASRKN 20082

Query: 1545  XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
                Y   A N  G  +    V +   P          +   V  E      +  +PP E 
Sbjct: 20083 TGEYTITASNPFGIKDEKVKVKVLDVP----GPPGPIEASSVSAE---KCTLTWLPPEED 20135

Query: 1605  IWYKNGNKLENDKEYN--ITTKEKTSVIRIK----ELKRSHSSKYTIEASNTAGTSSVEV 1658
                   + +   +E +  + TK   +V+  +    +L + +   + + A N  GT  V  
Sbjct: 20136 GGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYGTGDVTQ 20195

Query: 1659  T--LKVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
             +  +K+ D    P  P  P I   +S+ +VTI WK P  DGG ++  Y +E+ E    RW
Sbjct: 20196 SGPVKMVDSFGPPGPPSKPEI-DNVSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRW 20254

Query: 1714  IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXX 1772
             ++ +        + +  L+E  EY FRV A+N  GF E  E S+P++ K     P     
Sbjct: 20255 VRASKKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSN 20314

Query: 1773  XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKL 1829
                       + +  W     +GG  +  Y VE K+EG   W              +  L
Sbjct: 20315 PRITDTTKTTATF-NWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNL 20373

Query: 1830  SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWT 1887
                  Y FR+ A N  G   P   +  + +      P    +  + ++       +++  
Sbjct: 20374 QSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGASIRIF 20433

Query: 1888  EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
              P     +P   +  E   +KG++    +    S     I      D   + ++ EN  G
Sbjct: 20434 VPIKGRPAPEVVWYKENVPLKGRAH---IDTTESYTLVVIPECTRYDAGKYVLTLENVAG 20490

Query: 1948  VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
                 T   +VR+      P PP   L+ R +  + +   W  P  DGG+ +  Y I  R+
Sbjct: 20491 KK--TGFVNVRV---VDTPGPP-VNLKPREITKHSITLQWEIPLIDGGSKIKNYIIEKRE 20544

Query: 2008  VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
              T+  +  V   +     + I DL E   Y  R+ A NE+G+ EP E+ +P +
Sbjct: 20545 ATRKAY-SVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIR 20596



 Score =  146 bits (354), Expect = 6e-33
 Identities = 117/431 (27%), Positives = 191/431 (44%), Gaps = 18/431 (4%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPEGPVIMREISRESVTIEW 1687
             ++  L+     +Y + A N AG          +   D  + P  P +M  I+R SV++ W
Sbjct: 25282 KVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPSQPRVMN-ITRTSVSLSW 25340

Query: 1688  KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
               P  DGG ++T Y +E+ E  + RW+K    +     + +  L E+  Y FR+IA+N  
Sbjct: 25341 TKPEFDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRYDFRIIAKNAA 25400

Query: 1748  G-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKV 1804
             G FSE  ES  P+ +K  +D P           +  ++  I    +E +G   P+I +  
Sbjct: 25401 GLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAK 25460

Query: 1805  EIKQ-EGK-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGK 1861
             + K+ E K +++           ++      + Q+ +  +N  GT SL          G 
Sbjct: 25461 DGKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNCKVLDRPG- 25519

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
                P S P +  ++  T+   TL W  P+ NGG+ I +YI+E +     +WT +V     
Sbjct: 25520 ---PSSGPLD--ITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWT-LVYADMK 25573

Query: 1922  VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
                  +  + + +E IFR+   N  G     ES   +     TVP+ PT  +E+  V S 
Sbjct: 25574 ATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTVPAAPT-DVEVTSVTSE 25632

Query: 1982  IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
              +   W  P  DGG+ + GY I  R+ +   W+ V K  V  L+    +L E   Y  R+
Sbjct: 25633 AMTICWERPISDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRV 25692

Query: 2042  YARNEIGLSEP 2052
             +A N  GLS P
Sbjct: 25693 FAENAAGLSAP 25703



 Score =  144 bits (350), Expect = 2e-32
 Identities = 217/970 (22%), Positives = 374/970 (38%), Gaps = 63/970 (6%)

Query: 1135  ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTA---IL 1189
             A V W KDG  ++ +  +   +  +   L + +   DD G+Y+ ++ NS  + TA   ++
Sbjct: 21813 AAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVI 21872

Query: 1190  TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
              +++P         E +   + T ++   E  +    +  Y  +     T  + ++S   
Sbjct: 21873 VLDKPGPPTGPIKIEEVTADSVTLSWQPPEY-EGGCSINNYIVEKRDTSTTNWQIVSATV 21931

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSD 1304
              RT   +       CEY   +       KS+  +   VV ++P +I        ++  + 
Sbjct: 21932 ARTTT-KAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSATK 21990

Query: 1305  VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAGI-YKLR 1361
              +++V +          I+   I  K K++   +      +  T  K+   + GI Y+ R
Sbjct: 21991 ESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFR 22050

Query: 1362  L--ENNCG--HADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             +  EN  G   A     + +   P  PPGKP  + +  SS+ + W  P+  G   I  YV
Sbjct: 22051 VYAENIVGLSKASKVSEIQVARDPCDPPGKPEAVIVKRSSVTLRWTPPQFDGGIKITGYV 22110

Query: 1417  VEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA-SETTEYYKV 1473
             VE +E+    W+  S  NI +T+  +  L     Y FR  A N   +S   S++T    +
Sbjct: 22111 VEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTG--AI 22168

Query: 1474  IKETKIQSPTVEKPLK---NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY 1529
               + ++  P ++   K   N+     E   +     G P P V W + G++L  TA+   
Sbjct: 22169 TAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELTNTARLEI 22228

Query: 1530  ENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK--QKH 1584
             +N                   Y  +  N  GE      V +  +P        I      
Sbjct: 22229 KNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEKSVIINVKVLDRPGPPDGPISIYGVTSE 22288

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKY 1643
             K    W  T + +G    EV  Y    +  +   + +   K +T  ++I +L   +   +
Sbjct: 22289 KCCISWK-TPLHDG--GAEVSHYIVERRETSRLVWTVVELKVQTLNLKITKLLPGNEYIF 22345

Query: 1644  TIEASNTAGTSS-VEVTLKVYDKPS-KPEGP--VIMREISRESVTIEWKPPLDDGGLELT 1699
              +   N  G    +E    +   P   PE P  V +  I+++S+ I W+ P +DGG  +T
Sbjct: 22346 RVIPVNKYGIGEPLESDPVIAANPFVTPEAPSNVEVSNITKDSMVITWERPTNDGGSAIT 22405

Query: 1700  KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
              Y +EK + +  RW +          + +  L E   Y FRV A+N  G  +   S P V
Sbjct: 22406 GYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLLEMRSYEFRVSAENAAGVGKP--SPPTV 22463

Query: 1760  IKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXX 1816
                A D               +   SV + W     +GG  I  Y VE  +    +W   
Sbjct: 22464 YFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMC 22523

Query: 1817  X---XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                          +KL     Y+FRI A N+IG          + I   L  P    +  
Sbjct: 22524 TPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEAPDIDLDAD 22583

Query: 1874  VSES-TSRSV-TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
             + +  T R+  +L+   P     +P   +    KT    +    + +  S     IEN+ 
Sbjct: 22584 LRKMITVRAGGSLRLFVPIRGRPTPEVKW---GKTEGEINEAAQIDITSSFTSLVIENVN 22640

Query: 1932  EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
               D   + ++ EN  G    T+S  + +    T   P  A   ++ +  N V  +W  P 
Sbjct: 22641 RFDSGKYTLTLENASG----TKSAFISVRVLDTPDMP--ANFRVKEITKNSVTLTWEPPL 22694

Query: 1992  WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
              DGGA +  Y +  R+ T+ ++  V     N + + I  L E   Y  R+ A NE G+  
Sbjct: 22695 LDGGAKIKSYIVEKRESTRKVYSAV--TTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGL 22752

Query: 2052  PLESDEPFKV 2061
             P E+ EP K+
Sbjct: 22753 PAETPEPLKI 22762



 Score =  144 bits (349), Expect = 2e-32
 Identities = 137/560 (24%), Positives = 234/560 (41%), Gaps = 29/560 (5%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-------GD 785
            E P+++E ++S  V   + V    +V+G P P   W KN      L  KSD        D
Sbjct: 1849 EAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNG----ILLEKSDRVYWYWPED 1904

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
                 +++    +D     +KA N  G A + A + V+       +   F    ++   K
Sbjct: 1905 HVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQA-----KQVVSFTQTLEDAYAK 1959

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            EK T+      T  P   + W +NN  I   +    + D +   L +  ++ + D  +Y 
Sbjct: 1960 EKDTMVTFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQ-DDAEYS 2018

Query: 906  CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNK 964
            C   +        AR+ ++   +  VK+L+ S E  E  +   EC+ S       WY   
Sbjct: 2019 CAVVDD-DHIRTTARLYVEGAPLEIVKNLE-SVEVPETYSGEFECELSREDAEGTWYFEN 2076

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
            KEI+      +                 D G     V D +TS  L +K      ++ L 
Sbjct: 2077 KEITPSLKYVVSSRRGRHTLSVKDVRKEDQGKYTFKVGDLKTSATLKMKLRPVTLMQGLS 2136

Query: 1025 DFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
            D  + E D+A LEV  + E  +  W ++G  I      +    +  + KL + N +  D 
Sbjct: 2137 DLTICEGDIAQLEVRFSQENVEGTWMKNGLPISASDRVHIVIDK-LVHKLLVENVNKDDA 2195

Query: 1085 GEYSCI--LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFK 1141
            G YS +  ++D S + ++TV  +  EII+ L++    +G KA  E +++  D A V+W++
Sbjct: 2196 GIYSFVVPIQDISTSGKLTVQSI--EIISHLKDVHSIEGTKAVLEAKISASDVAAVKWYQ 2253

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201
            +   +  S  IQ+   G KQ+L +      D G+Y   VG  + T  LTVE+ SI   ++
Sbjct: 2254 NDKLLVASERIQMVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKVSI---IK 2310

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
              E  +     +    VE+    +D  W  K   ++   K+ + S  K  +L I    +D
Sbjct: 2311 HMEDCVCTETQNVTFEVELSHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINAMKD 2370

Query: 1262 DQCEYTCVLLDAKSTTKLKV 1281
            ++  Y     +  S+ KL V
Sbjct: 2371 EEGLYAFAAGEKISSAKLTV 2390



 Score =  141 bits (341), Expect = 2e-31
 Identities = 112/431 (25%), Positives = 183/431 (42%), Gaps = 23/431 (5%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYD---KPSKPEGPVIMREISRESVT 1684
             R+  L    S ++ + A N AG    S   V  K  D   KP  P  P +   +SR SV 
Sbjct: 22433 RVTGLLEMRSYEFRVSAENAAGVGKPSPPTVYFKAADPVFKPGPPNNPKVAY-VSRASVV 22491

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIA 1743
             + W  P+ DGG E+  Y +E  E  ++ W+         ET +  +KL E  EY FR+ A
Sbjct: 22492 LHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITETRFEAKKLLEKHEYKFRICA 22551

Query: 1744  QNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIID 1801
              N +G  E  +    ++I+  L+ P           I       +  F   +   +P + 
Sbjct: 22552 VNKIGVGETADIPGSVIIEDKLEAPDIDLDADLRKMITVRAGGSLRLFVPIRGRPTPEVK 22611

Query: 1802  YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             +     +  +  +           I+ ++   + ++ +   N  GT   + S       +
Sbjct: 22612 WGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLTLENASGTKSAFIS------VR 22665

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
              L  P  P NF V E T  SVTL W  P  +GG+ I +YI+E +    K ++ + T    
Sbjct: 22666 VLDTPDMPANFRVKEITKNSVTLTWEPPLLDGGAKIKSYIVEKRESTRKVYSAVTTCNKM 22725

Query: 1922  VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
               +  IE ++E     FR+ AEN  G+ LP E+      K + VP PP   + +  V   
Sbjct: 22726 TWK--IEPLEEGSIYFFRVLAENEHGIGLPAETPEPL--KISEVPQPP-GKVSVVDVTRK 22780

Query: 1982  IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
              V   W  PE DGG+ +  Y + ++   +  W    +  V  L   + +L++   Y+ R+
Sbjct: 22781 SVSLKWEKPEHDGGSRITYYEVEMQAKDQDKWSLCAQ--VKALDTVVTNLAQGGEYIFRV 22838

Query: 2042  YARNEIGLSEP 2052
              A N+ G S+P
Sbjct: 22839 IAVNDKGKSDP 22849



 Score =  140 bits (340), Expect = 3e-31
 Identities = 91/320 (28%), Positives = 143/320 (44%), Gaps = 9/320 (2%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KW-KXXXXXX 1820
             LD P           I  +SV + W P   +GGSPI +Y V +K+E     W +      
Sbjct: 26202 LDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV-LKRETTTANWIEVSSAVA 26260

Query: 1821  XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                 +I KL+    YQFRI A N  G S  +     +T+    T P  P    VS  T  
Sbjct: 26261 RCTIKIMKLNTGVEYQFRIKAENRFGIS-EHIDSQTVTVSLPYTLPVAPSQPWVSAVTKE 26319

Query: 1881  SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
             S+ + W EP S+GGS +  Y ++ K      W K+ T         + N+       F++
Sbjct: 26320 SIVVNWKEPSSDGGSHVFGYHLQMKDRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKV 26379

Query: 1941  SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
             +AEN  G+   ++S    L   A    PP + + +  +  N +  +W  P +DGG+ + G
Sbjct: 26380 AAENAAGIGPISKSSDPVLAIDAC--EPPNS-VRVTDITKNSISLAWQKPSYDGGSKITG 26436

Query: 2001  YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEPF 2059
             Y I ++D  K  W +    +V   KF +  L++N +Y  R+ A+N +G +S P E   P 
Sbjct: 26437 YLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPV 26496

Query: 2060  KVIPGEGSHADEEPGEQTEV 2079
               +   G+   + P E  +V
Sbjct: 26497 TCVDTYGAPEVDLPQEYLDV 26516



 Score =  140 bits (339), Expect = 4e-31
 Identities = 111/442 (25%), Positives = 194/442 (43%), Gaps = 26/442 (5%)

Query: 1630  IRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDK---PSKPEGPVIMREISRESV 1683
             ++   L+     +Y + A N AG S+  V     K  D    PS P  P I+ + ++ SV
Sbjct: 25677 VKASNLREGCEYEYRVFAENAAGLSAPSVPCPLTKAEDPLFLPSPPAKPKII-DSTKTSV 25735

Query: 1684  TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             T+ W  PL DGG  +T Y +E    +++ W    +  +  E + +  L    EY+F V +
Sbjct: 25736 TLSWNKPLFDGGSPVTGYMVEYRNTNDDDWTVGVNNTKSTE-FTVVGLTSGTEYVFVVRS 25794

Query: 1744  QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXX--IDNESVYITWFPSEKNGGSPII 1800
              N +G SE + E++P V K   D P             + + S +    P +      ++
Sbjct: 25795 INKIGPSEPSPETDPQVAKEREDEPVFLISNEMRKTLVVKDGSSFTLRVPFKGKPVPHVM 25854

Query: 1801  DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
               K ++    +              I++ + + + ++ +  +N  GT+        +T+ 
Sbjct: 25855 WNKPDVDLRVRA-SIDTTDTCTSVTIEQATRDDSGKYTVTLQNVAGTAT-------LTLS 25906

Query: 1861  -KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919
              K L  P  P +  V E T  S T+ W  P++ GG+P+ NY+++ +      W++I    
Sbjct: 25907 VKVLDSPGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYLVDLREATKMGWSRISNSC 25966

Query: 1920  GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
               +  + + N++E     FR++ EN  GV +P E++     K    PSPP   L +  V 
Sbjct: 25967 PRL-TYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEG--TKITEKPSPP-PKLGVTDVT 26022

Query: 1980  SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
                V  +W  PE DGG+ +  Y +   +  +  W++ G     +  F +  L EN  Y  
Sbjct: 26023 KESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCG--STKSTHFVVDGLRENAEYYF 26080

Query: 2040  RIYARNEIGLSEPLESDEPFKV 2061
             R+ A N  GLS+P +   P  V
Sbjct: 26081 RVRAENHAGLSDPKDMVLPVLV 26102



 Score =  140 bits (338), Expect = 5e-31
 Identities = 156/605 (25%), Positives = 243/605 (40%), Gaps = 45/605 (7%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437
             P PP  P +++   SSI++ W +P   G   I+ Y+VE++  D  EW+     KN+  T+
Sbjct: 19260 PGPPAFPKVVDSTHSSISLSWTKPAYDGGCEILGYLVEFKRADAEEWMKCNVPKNLQATK 19319

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
              ++  L  N+ Y+FR  AVN++   + SE  E  K + +  + +P  E      K +   
Sbjct: 19320 FNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPE--KHLAKDILLAPEAELDADLRKALVLR 19377

Query: 1495  PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKC 1550
                 + +     G P PK TW +    LK  +     T E                 Y  
Sbjct: 19378 AGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYDAGKYVL 19437

Query: 1551  IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYK 1608
                N  G    + VV +   P   + N  +K+  K  V   W    +  G P    +  K
Sbjct: 19438 TLENSSGTKSYTIVVKVLDTPGPPV-NLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEK 19496

Query: 1609  NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                +L   K +     E  KTS  RI  L+   +  + + A N  G      T     K 
Sbjct: 19497 ---RLAERKAWTCVAPECPKTS-FRITNLEAGQAYCFRVLAENIYGIGEGCETAGPV-KA 19551

Query: 1667  SKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             S+  GPV      EI++ S T+ WK P+ DGG  +  YA+E  E ++ +W  +  +   V
Sbjct: 19552 SEQPGPVAEFKSMEITKNSCTLGWKKPISDGGSHVVAYALEICEGED-KWKLL--MKSKV 19608

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX-XXXXIDNE 1782
               Y I  L E  EY FRV A N        E   I+ K  +  P+           +  E
Sbjct: 19609 TQYTIGDLVEGKEYSFRVKAINESAEGPPTELT-ILAKDQIVPPNCDLKGLPDSSYVAKE 19667

Query: 1783  SVYITWFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839
                +          +P + +K   V +   G+              I+        +F I
Sbjct: 19668 GTTVRLNIPITGIPAPAVIWKKGDVTLSDSGRI-SVESTTTNTVLLIRDCHRGDAGKFTI 19726

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
               RN  GT      D K+ +GK     S P  F   E T+ ++T++W  P+ +GGS +TN
Sbjct: 19727 ILRNSAGTK-EAAIDIKV-VGKPGIC-SGPIKF--DEITAEAITVEWGPPKDDGGSEVTN 19781

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
             Y +E +      W   VTV  ++ ++   +  + +  E IFR+ AEN  G+     S  V
Sbjct: 19782 YFLEKRHSTANKW---VTVASAIQKNSMRVTRLHDGTEYIFRVCAENKYGIGEFLRSDPV 19838

Query: 1958  RLEKH 1962
              L KH
Sbjct: 19839 -LAKH 19842



 Score =  138 bits (335), Expect = 1e-30
 Identities = 167/713 (23%), Positives = 278/713 (38%), Gaps = 54/713 (7%)

Query: 1379  DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKT 1436
             D   PPG P  + +   S+ + W  PE  G S +  YVVE +++    W+  S  NI +T
Sbjct: 23154 DPCDPPGTPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVEKRDLPEGRWMKASFANILET 23213

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKN---IT 1492
             + ++  L  +  Y FR  A N    +S  SE+T    V  + +++ PT E   +    +T
Sbjct: 23214 EFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTG--SVTAKDEVEPPTYEVASEYSQILT 23271

Query: 1493  TEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYEN---RXXXXXXXXXXXXXXXY 1548
                 +   L     G P P + W++   +++ +A+A  +N   +               Y
Sbjct: 23272 VNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEIKNTDFKAVLVVKDAIRIDGGQY 23331

Query: 1549  KCIAFNDHGEVETSCVVGIQQKP-----VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
                  N  G    S  V +  +P      +T+S        K    WL      G     
Sbjct: 23332 TLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVT---NEKCSLSWLPPRHDGG---SS 23385

Query: 1604  VIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLK 1661
             + +Y    +  +   + + + +   ++ ++ +L + +   + + A N  G    +E    
Sbjct: 23386 ISYYVIQKRETSRLAWTVVSGDCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEPLESRAV 23445

Query: 1662  VYDKPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             +   P    GP   + +  ISR+S+T+ W  P  DGG E+  Y +EK +    RW K   
Sbjct: 23446 IMRNPFVAPGPPQDLEITNISRDSMTVCWTRPESDGGNEIVGYIVEKRDRAGIRWTKCNK 23505

Query: 1719  VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778
                    + +  L E+ EY FR+ A+N  G  +   S+P V   A D             
Sbjct: 23506 RRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQP--SQPTVYYKACDPTFKPGQPTNAHL 23563

Query: 1779  IDN--ESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXX---XXXXXXARIQKLSIN 1832
             +D    SV + W     +GG  I  Y VEI K + ++W               I KL+ +
Sbjct: 23564 VDTTKNSVTVAWSRPIYDGGLDIQGYVVEISKADEEEWITCTPPTGLNDTKFSITKLTEH 23623

Query: 1833  TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
               Y+ RI A N++G   P      +   K +     P   + SE     V          
Sbjct: 23624 QEYKVRICALNKLGVGEPVPIQGSV---KPVDKMDAPEIELDSELRKGIVV-------HA 23673

Query: 1893  GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             GGS   N   + + +   +WTK    G    +  I+   +   +   I   N  G    T
Sbjct: 23674 GGSMRINIPFKGRPIPEINWTK--DDGDLPDKAQIDKGPDFTHLTINICDRNDAGKYTLT 23731

Query: 1953  ESQSVRLEK---HATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
                S   +       V   P AP  L ++ +  N V   W  P  DGG+ +  Y I  R+
Sbjct: 23732 LQNSAGTKSAFVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIIDKRE 23791

Query: 2008  VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
              T+  +  +     +   F + DL+E   Y  R+ A NE G+  P+E++E  K
Sbjct: 23792 STRQGFTNI-TTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVK 23843



 Score =  137 bits (332), Expect = 3e-30
 Identities = 167/772 (21%), Positives = 301/772 (38%), Gaps = 57/772 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F KK  +    EG  +  ECR+      +++WL  GE +  D   +++ + +     
Sbjct: 7218 PPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNS---- 7273

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +VL I   +    G YT VA N  G AS    L ++   + PP   + L  + V  G++V
Sbjct: 7274 AVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQE-PRYPPVFDKKLVPVDVSVGDTV 7332

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L   + G+    +TW K++K ++           +T  +TILK  K  D G Y+  A N
Sbjct: 7333 ELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKA-DSGRYSCHASN 7391

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK--EKGTIKLVARVTRNPVPSITWY 867
              G    S  ++V+E       PP F  +    T++  E   +K+  RV  +   ++ WY
Sbjct: 7392 DVGKDSCSTEVSVKE----RKIPPSFTKK-PSTTIEDIEGKVVKIEGRVAGSQPLTVNWY 7446

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++   I  S+     F      L I       DSG Y C A+N AG +S    V I  +K
Sbjct: 7447 KDGREIFTSDFYDVTFKSSLAVLCIKKSQLS-DSGTYVCKATNEAGTASFEVSVHITAQK 7505

Query: 928  VTFVKHLQ-KSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
            V     L  K     EG+T+ L C    S  +  +W  +++E+S   + +I         
Sbjct: 7506 VPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFVDGTATL 7565

Query: 985  XXXXXXXXDVGVIKCIVKDQETS-----TMLVVKETIPEFIRKLQDF---------EVKE 1030
                    D G   C   ++  +            + P+ ++K  +           + E
Sbjct: 7566 EMTRVSKTDSGDYLCKATNEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVE 7625

Query: 1031 KDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            K  A    ++  +   +V W +          +   E++G   K+ I+  +  D G+Y C
Sbjct: 7626 KGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRISIEQKGQEAKMEIKEVTKSDSGQYRC 7685

Query: 1090 ILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145
            +  ++     C+ ++ V E     +  ++ +K     K+  E +      L+R       
Sbjct: 7686 VASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPSKQKSPKEEKDIDIVELLRNVDPKEY 7745

Query: 1146 IQFSNHIQLT-IDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203
             +++    +T   G  Q ++    + + ++G    E+   +    L      +   +   
Sbjct: 7746 EKYARMYGITDFRGLLQAIEFLKKEKELESGRPEGEIVGRESEEDLAKLVADLQKRMEQT 7805

Query: 1204 EFILVPAN-TDAYLTVE----------IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            E + V  + TD   TV+          I    + ++WYK    ++  +K+ +     +  
Sbjct: 7806 EPVTVARDITDQTTTVKKEAVFECEIKINYPEITLSWYKGTQKLDSGDKYDIKIVGDRHI 7865

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
            L I+ C   D+  Y  V     S+ KL V   E    + D       K G   TL     
Sbjct: 7866 LKIKDCQTRDEGNYRIVCGPHISSAKLTVLEAEVEKPMQDVAG----KEGQTCTLTCQLS 7921

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
              P    +W  N K+++       ++ + +  L+IK V   D G Y  + +N
Sbjct: 7922 V-PNVKTQWFRNGKLLEPHSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKN 7972



 Score =  136 bits (328), Expect = 8e-30
 Identities = 163/676 (24%), Positives = 279/676 (41%), Gaps = 48/676 (7%)

Query: 1216  LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL--- 1271
             LT +I    L ++ WY+    +  + K+ + SD +  +L +    ++D+  YTC  +   
Sbjct: 30185 LTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRAVNEA 30244

Query: 1272  -DAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
              + +++ KL ++   +F P     + +Y    G+ + L V Y   P P   W    K + 
Sbjct: 30245 GEIETSGKLLLQAAPQFHPGF-PLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLN 30303

Query: 1330  KCKHTKPSIDSKSASLTIKKVEN-TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
               ++           L I+ V+  T+AG YK++L N  G  D  + V I DKP  P  P 
Sbjct: 30304 PSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLPEGPV 30363

Query: 1389  ILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKN-ITKTQTSIQNLKT 1445
             +++ +  SS+ I W  P++ G S I  Y+VE +E  +  +W  V + ++ T   + NL  
Sbjct: 30364 VVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRVPNLIE 30423

Query: 1446  NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIEL--- 1501
             +S Y FR  A N+  IS++ E      VI ++  + P V ++P  +  T+ +  +     
Sbjct: 30424 SSGYYFRVSAQNQYGISESLEIPSV--VIIKSPFEKPGVPQRPFVSSVTKDSCVVSWKPP 30481

Query: 1502  TCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAF---N 1554
             T   G   +      R+ K+ K    T    +E                  KC      +
Sbjct: 30482 TSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCENIGGES 30541

Query: 1555  DHGEVETSCVVGIQ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             D  E+    +       + P       D+  K+K  +   VT V+ G P P V WYKNG 
Sbjct: 30542 DWSEISEPVIPKSDTALRAPFFKDELRDMCVKYK-ANATFVTKVV-GHPKPVVKWYKNGK 30599

Query: 1612  KLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSS------VEVTLKVY 1663
             ++  D       + K    +  I     + ++ Y I A+N  G+ S      VEV  K+Y
Sbjct: 30600 EILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIY 30659

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
               P   +G   +  I  E VTI  K P+      +  +   +   +N  + +V       
Sbjct: 30660 -LPLHLQGMGAVHAIRGEVVTI--KIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFT 30716

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
                 ++ +       + + A+N  G    ++ + + +  A DVP           I  ++
Sbjct: 30717 SLVFLKGVQRKDSGYYIICAKNRFG----MDKQTVELDVA-DVPD-PPKDVKVSDIGRDT 30770

Query: 1784  VYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
             + +TW P   +GGS II+Y +E     G +W            +  L   T YQFR+ A 
Sbjct: 30771 LTLTWSPG-NDGGSEIINYIIEKCPTTGDRWIRVAQTSESQYTVMSLFGKTKYQFRVIAE 30829

Query: 1843  NEIGTSLPYTSDDKIT 1858
             N  G S P    D +T
Sbjct: 30830 NRFGVSDPSAPTDPVT 30845



 Score =  135 bits (327), Expect = 1e-29
 Identities = 178/772 (23%), Positives = 308/772 (39%), Gaps = 64/772 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMY 691
            PP F KK     V  G  + LEC +       + W    ++I    N  ++ +E+  H+ 
Sbjct: 7314 PPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHL- 7372

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             ++LK     K   G Y+  A N  G+ S    + +K  +  P    +P  ++   +G+ 
Sbjct: 7373 -TILK---ADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPPSFTKKPSTTIEDIEGKV 7428

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL--KPKKVKDEGVYTLKAEN 809
            V +  +V G+   T+ W K+ + +            S+ +L  K  ++ D G Y  KA N
Sbjct: 7429 VKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKATN 7488

Query: 810  SEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
              G A  E S  IT ++       PP F    + +TV E  T+ L   V  +P   I W 
Sbjct: 7489 EAGTASFEVSVHITAQKV------PPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWM 7542

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVE 926
            ++   +S S      F      L +T V S+ DSGDY C A+N AG K    A       
Sbjct: 7543 KDRRELSSSANTKITFVDGTATLEMTRV-SKTDSGDYLCKATNEAGNKPGAPAPAQAAPS 7601

Query: 927  KVTFVKHLQKSYETEEGKTV-ILECQTSHTVS---------TKWYHNK-KEISGMDHREI 975
                VK     +  E  K+V I+E  T+  ++          KW   K ++++      I
Sbjct: 7602 PPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRISI 7661

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV---KETIPEFIR-----KL 1023
             Q+G+            D G  +C+  ++    E ST L V   KET  E ++       
Sbjct: 7662 EQKGQEAKMEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPSK 7721

Query: 1024 QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
            Q    +EKD+ I+E+  N +  +  +E+   +      +   +    ++K      S   
Sbjct: 7722 QKSPKEEKDIDIVELLRNVDPKE--YEKYARMYGITDFRGLLQAIEFLKKEK-ELESGRP 7778

Query: 1084 EGEYSCILRDESCTAEVT-----VVELPPEIITR-LQNQKVNKGNKATFE--IELTKGDA 1135
            EGE      +E     V      + +  P  + R + +Q      +A FE  I++   + 
Sbjct: 7779 EGEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTVKKEAVFECEIKINYPEI 7838

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
             + W+K   ++   +   + I G +  LKI DC   D G Y    G    +A LTV E  
Sbjct: 7839 TLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTRDEGNYRIVCGPHISSAKLTVLEAE 7898

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
            +   +   + +         LT ++    +   W++   ++E   ++T       + L I
Sbjct: 7899 VEKPM---QDVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEPHSRYTCAVANYTQKLSI 7955

Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
            +    +DQ EYTC   + ++T  L +E   + F  +I +           +  +  D   
Sbjct: 7956 KDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRIQNIVVREHQSATFECEVSFDNAV 8015

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK--LRLE 1363
                 D W    ++ +  K+T  S + +   + I+ V + D G+Y   +RLE
Sbjct: 8016 VTWYKDTW----ELKESPKYTFRS-EGRRHFMIIRNVSSADEGVYSVIVRLE 8062



 Score =  133 bits (321), Expect = 6e-29
 Identities = 96/334 (28%), Positives = 142/334 (42%), Gaps = 12/334 (3%)

Query: 1728  IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
             I++ N      + + A N +G     E   I+I   LD P           +    V I+
Sbjct: 24006 IKEANREDSGKYTITATNNIG--TVTEEVAIII---LDKPGPPTGPVKIDEVSATYVVIS 24060

Query: 1788  WFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEI 1845
             W P    GG  I +Y VE +      W+           +I KL   + YQFR++A N  
Sbjct: 24061 WEPPVYTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRY 24120

Query: 1846  GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
             G S    S   + +    T P+ P    VS  T   +T++W  P +NGGSPI  Y +E K
Sbjct: 24121 GKSGSIDSTP-VVVSYPFTEPAAPGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERK 24179

Query: 1906  TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965
                   WTK+  +  +        ++E  E  +R+ AEN  G+S    S  V     A  
Sbjct: 24180 EKNSILWTKLNKLLITDTRLRTNGLEEGIEYEYRVFAENIAGIS---PSSKVSESVVARD 24236

Query: 1966  PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
             P  P    E  ++  N++   W  P++DGG+ + GY I  + +    WM+    ++   +
Sbjct: 24237 PCDPPGTPEAIVITRNLITLQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQ 24296

Query: 2026  FNIRDLSENHTYMIRIYARNEIG-LSEPLESDEP 2058
             F I  L E   Y  R+ ARN  G LS P ES  P
Sbjct: 24297 FTITGLHEEQRYEFRVIARNAAGILSVPSESTGP 24330



 Score =  132 bits (318), Expect = 1e-28
 Identities = 108/433 (24%), Positives = 183/433 (42%), Gaps = 26/433 (6%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK------PSKPEGPVIMREISRESVT 1684
             R   L   H  ++ + A N AG  +     + Y        P  P  P +  + S  +V+
Sbjct: 24597 RATGLTEGHFYEFRVSAENAAGVGTPSEPSEYYKACDATYPPGPPNNPKVT-DHSSTTVS 24655

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             + W  P+ DGG  ++ Y +E  + + + W +           + ++KL EN EY FR+ A
Sbjct: 24656 LAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICA 24715

Query: 1744  QNPVGFSEALESEPIVIKTA-LDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIID 1801
              N  G  E ++    VI    L+ P           +    S  +  F + +    P + 
Sbjct: 24716 VNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFVTIRGRPEPEVK 24775

Query: 1802  YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             +K       ++ +           I  ++   T ++ +   N IG+   + +       K
Sbjct: 24776 WKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLTLENNIGSKSAFVNV------K 24829

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VG 1919
              L  PS P NF V +    SV L+W  P+ +GG+ IT+YI+E +  K  ++T I    V 
Sbjct: 24830 VLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAKITHYIVEKRESKRLAFTSITNNCVR 24889

Query: 1920  GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
              S+    +++++E     FR+ A N +GV LP E  +    K +  P PP   + +  V 
Sbjct: 24890 NSIR---VDDLQEGGLYHFRVLAVNELGVGLPAE--TTEAVKISQAPLPP-GKITVIDVT 24943

Query: 1980  SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
              + V  SW  P+ DGG+ + GY + +       W     V +  L+  I  L+    Y  
Sbjct: 24944 RHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKW--TACVTIKALEATIEGLTTGEEYSF 25001

Query: 2040  RIYARNEIGLSEP 2052
             RI A N+ G S+P
Sbjct: 25002 RITAINDKGKSDP 25014



 Score =  131 bits (317), Expect = 2e-28
 Identities = 89/330 (26%), Positives = 142/330 (43%), Gaps = 11/330 (3%)

Query: 1739  FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
             + + A NP G    ++ E + +K  LDVP           +  E   +TW P E++GG  
Sbjct: 20086 YTITASNPFG----IKDEKVKVKV-LDVPGPPGPIEASS-VSAEKCTLTWLPPEEDGGCS 20139

Query: 1799  IIDYKVEIKQEGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
             I  Y +E ++  +             R    KL     Y FR+ A N+ GT    T    
Sbjct: 20140 IKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYGTG-DVTQSGP 20198

Query: 1857  ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
             + +  +  PP  P    +   +  +VT+ W  P  +GGS I  YI+E K  +G  W +  
Sbjct: 20199 VKMVDSFGPPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRWVRAS 20258

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEI 1975
                 S     +  + E+ E  FR++AEN  G   P+E SQ V  +  A  P PP+ P  I
Sbjct: 20259 KKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNP-RI 20317

Query: 1976  RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
                       +WG P +DGG  + GY +  +      W++   + +   +F + +L    
Sbjct: 20318 TDTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNLQSGG 20377

Query: 2036  TYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065
              Y  R+ A N  GL EP E ++  +++  E
Sbjct: 20378 KYHFRVSALNSEGLGEPSEVEQVVELVDRE 20407



 Score =  131 bits (317), Expect = 2e-28
 Identities = 84/298 (28%), Positives = 136/298 (45%), Gaps = 6/298 (2%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-X 1821
             LD P           +  E   +TW P ++NGG+ I  Y VE ++  +  W         
Sbjct: 25515 LDRPGPSSGPLDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVYADMKA 25574

Query: 1822  XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                ++ KL     Y FR+   N+ GT     SD    +    T P+ P +  V+  TS +
Sbjct: 25575 TTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDP-FTVPAAPTDVEVTSVTSEA 25633

Query: 1882  VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
             +T+ W  P S+GGS I+ Y+IE +   G  W ++             N++E  E  +R+ 
Sbjct: 25634 MTICWERPISDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVF 25693

Query: 1942  AENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
             AEN  G+S P+      + E    +PSPP  P  I    +++ + SW  P +DGG+P+ G
Sbjct: 25694 AENAAGLSAPSVPCPLTKAEDPLFLPSPPAKPKIIDSTKTSVTL-SWNKPLFDGGSPVTG 25752

Query: 2001  YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             Y +  R+     W  VG  +  + +F +  L+    Y+  + + N+IG SEP    +P
Sbjct: 25753 YMVEYRNTNDDDW-TVGVNNTKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDP 25809



 Score =  130 bits (315), Expect = 3e-28
 Identities = 117/565 (20%), Positives = 231/565 (40%), Gaps = 36/565 (6%)

Query: 1317  PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375
             P   +IV  + +++          K    T+  +      ++++  EN  G ++  E+  
Sbjct: 13829 PITNYIVEKRDVRRKGWQAVDTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELED 13888

Query: 1376  TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
             ++L K     P PP    I E+  + +++ W+ P+N G   ++ YV+E +E   T W+  
Sbjct: 13889 SVLAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKS 13948

Query: 1431  KNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
                +       + ++   +  +F+  A NE  +   SE T+   V+ E     P+  + L
Sbjct: 13949 GKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDI--VVIEDPTGPPSPPQEL 14006

Query: 1489  KNITTEPNEDIELTCIF----GGVP----------QPKVTWYR-DGKKLKTAKATYENRX 1533
              +IT    + I +        GG P               W R + + +K  K    +  
Sbjct: 14007 -HITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNSRPVKELKYRAGDEE 14065

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                              +  ++  ++ E    +     P +    +D+      G++  +
Sbjct: 14066 GIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCSPTLDFQTKDLVVVE--GEKMHL 14123

Query: 1593  TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                   +P P++ W+K+GN+++ D       +  +  + +     + + +Y +   N  G
Sbjct: 14124 PIPFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLEVPSCLHADAGQYKVTLENRNG 14183

Query: 1653  TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
              +S  + +KV   P  P   ++  EI++ S  + W+PP  DGG  +  Y +++ E     
Sbjct: 14184 ATSGTINVKVIGLPG-PCKDIVASEITKSSCKVSWEPPDYDGGSPILHYVLQRREAGRRT 14242

Query: 1713  WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXX 1771
             ++KV   +  + ++ ++ L +N EY FRV A N +G  E +E   P++ +     P    
Sbjct: 14243 YVKVMSGENKL-SWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPPV 14301

Query: 1772  XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQK 1828
                      +ESV +TW P   +GGS I+ Y +E   +G+   +             ++ 
Sbjct: 14302 DVETHNP-TSESVTLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKG 14360

Query: 1829  LSINTTYQFRIYARNEIGTSLPYTS 1853
             L+    YQFR+ A N  G S P  S
Sbjct: 14361 LTHEKQYQFRVRAENAAGVSDPSRS 14385



 Score =  129 bits (311), Expect = 9e-28
 Identities = 139/601 (23%), Positives = 238/601 (39%), Gaps = 33/601 (5%)

Query: 1499  IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXX----XXXXXYKCIAF 1553
             + L  ++ G P P++ W+   K L  ++    EN                    YK    
Sbjct: 30279 LRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLS 30338

Query: 1554  NDHGEVETSCVVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             N  G V+T   V IQ KP++       D   K  V   W       G      I  K   
Sbjct: 30339 NKFGTVDTVLRVEIQDKPLLPEGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREA 30398

Query: 1612  KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665
             K E ++ + +++    +  R+  L  S    + + A N  G S      SV +    ++K
Sbjct: 30399 K-EGEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEK 30457

Query: 1666  PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
             P  P+ P +   ++++S  + WKPP  DGG ++  Y +EK E   N+WI V   +    +
Sbjct: 30458 PGVPQRPFVS-SVTKDSCVVSWKPPTSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETS 30516

Query: 1726  YCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             Y  + L E  EY FRV  +N  G S+  E SEP++ K+   + +                
Sbjct: 30517 YTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDTALRAPFFKDELRDMCVKYKA 30576

Query: 1785  YITWFPSEKNGGSPIID-YK--VEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIY 1840
               T+         P++  YK   EI  +G K K            I     N    ++I 
Sbjct: 30577 NATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIR 30636

Query: 1841  ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
             A N++G+     + D     K   P        V       VT+K   P S    P+  +
Sbjct: 30637 ATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKI--PISGKPDPVVTW 30694

Query: 1901  IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
                 + +   ++ +++          ++ ++ KD   + I A+N  G+    + Q+V L+
Sbjct: 30695 QKGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGM----DKQTVELD 30750

Query: 1961  KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
               A VP PP   +++  +G + +  +W +P  DGG+ ++ Y I     T   W+ V +  
Sbjct: 30751 V-ADVPDPPK-DVKVSDIGRDTLTLTW-SPGNDGGSEIINYIIEKCPTTGDRWIRVAQTS 30807

Query: 2021  VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS--HADEEPGEQTE 2078
              +  ++ +  L     Y  R+ A N  G+S+P    +P      + +  + DEE  E  E
Sbjct: 30808 ES--QYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDPVTTKEDKLAIRNYDEEVDETRE 30865

Query: 2079  V 2079
             V
Sbjct: 30866 V 30866



 Score =  127 bits (307), Expect = 3e-27
 Identities = 87/302 (28%), Positives = 133/302 (44%), Gaps = 7/302 (2%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
             +D+P           +D ++  + W    ++GGS I +Y VE     +  W         
Sbjct: 18659 MDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSNITNYIVEKCDVTRGDWVTAVSCTKT 18718

Query: 1823  XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
               R+ KL+    Y FR+ A N  G S P  S+ K+       PPS+P N  V++ +   V
Sbjct: 18719 SCRVGKLTCGKEYGFRVRAENRFGISEPIYSE-KMIARHPFDPPSEPLNCCVNKVSKEFV 18777

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
              L W +P ++GGS +T Y IE K      W +   V     E+    + E  E  FR+SA
Sbjct: 18778 VLSWEKPVNDGGSALTGYFIERKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFRVSA 18837

Query: 1943  ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
              N  G   P++ Q+  +   + V  PP  P EI  V  + V   W  P+ DGG+ L+GY 
Sbjct: 18838 VNKAGQGKPSK-QTDFITARSPV-DPPGKP-EIIDVTKSSVSLVWSRPKHDGGSKLIGYY 18894

Query: 2003  IAIRDVTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             +    + +  W+ V     N  K  + +  L E   Y  RI A+  I +S P E  +   
Sbjct: 18895 VEFLKLKEDKWVRVNSNSQNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIP 18954

Query: 2061  VI 2062
             +I
Sbjct: 18955 II 18956



 Score =  125 bits (301), Expect = 2e-26
 Identities = 118/447 (26%), Positives = 201/447 (44%), Gaps = 37/447 (8%)

Query: 1626  KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISR 1680
             KTS  R+ +L       + + A N  G S    + K+     +D PS+P    +  ++S+
Sbjct: 18717 KTSC-RVGKLTCGKEYGFRVRAENRFGISEPIYSEKMIARHPFDPPSEPLNCCV-NKVSK 18774

Query: 1681  ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
             E V + W+ P++DGG  LT Y IE+ E ++  W++  +V      Y    L E  EY FR
Sbjct: 18775 EFVVLSWEKPVNDGGSALTGYFIERKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFR 18834

Query: 1741  VIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             V A N  G  + + +++ I  ++ +D P           +   SV + W   + +GGS +
Sbjct: 18835 VSAVNKAGQGKPSKQTDFITARSPVDPPGKPEIID----VTKSSVSLVWSRPKHDGGSKL 18890

Query: 1800  IDYKVE-IKQEGKKWKXXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
             I Y VE +K +  KW           +    +  L     Y+FRI A+  I  S+P    
Sbjct: 18891 IGYYVEFLKLKEDKWVRVNSNSQNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEES 18950

Query: 1855  DKITIGKTLTPPS-----QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
             D I I     PP      + +N +V ++   +V L   E E   G P+   ++  K    
Sbjct: 18951 DVIPIIAEHVPPRVEISLEMKNLIVVKA-GANVCL---EAEVY-GKPMPK-VVWKKDGAP 19004

Query: 1910  KSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
                 + + +   VH   +E  ++  K+   + I+AEN  G    ++S +++L K    P 
Sbjct: 19005 LKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSG----SKSANIKL-KVLDKPG 19059

Query: 1968  PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKF 2026
             PP A + I  V ++ V   W  P  DGG+ +  Y +  R+ ++  W +V   ++      
Sbjct: 19060 PP-ASVRISHVFADRVKLRWEPPLADGGSEITNYIVDKRETSRANWAQVTANINGQITDC 19118

Query: 2027  NIRDLSENHTYMIRIYARNEIGLSEPL 2053
             ++  L E H Y  RI A N+ G+ +P+
Sbjct: 19119 SVEKLIEGHEYEFRISAENKYGVGDPI 19145



 Score =  124 bits (298), Expect = 4e-26
 Identities = 109/452 (24%), Positives = 202/452 (44%), Gaps = 33/452 (7%)

Query: 1616  DKEYNITTKEKTSVIRIKELKRSHSS-----KYTIEASNTAGTSSVEVTLK--VYDKPSK 1668
             D+   +  K  T+VIR    K ++ +     ++ + A N AG   +  +    +     +
Sbjct: 26345 DRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACE 26404

Query: 1669  PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YC 1727
             P   V + +I++ S+++ W+ P  DGG ++T Y IE  +    RW K A++    +T + 
Sbjct: 26405 PPNSVRVTDITKNSISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSK-ANLTNVTDTKFT 26463

Query: 1728  IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
             +  L +N  Y FRV+A+N VG S +  SE +   T +D             +D       
Sbjct: 26464 VSGLTQNESYEFRVMAKNAVG-SVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAG 26522

Query: 1788  WFPSEKNG----GSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLS-INT-TYQFRI 1839
                  K G      P I++  + K+   G +             +++ + +NT TY+ +I
Sbjct: 26523 ATVQLKIGIVAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKI 26582

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
               +N +G++       ++ +     PP+    F   + T+ ++T+ W  P   GG+ +T+
Sbjct: 26583 --KNSLGSAYAAV---RVLVQDKPGPPAGEIQF--KKITADTMTIMWDPPADEGGAMVTH 26635

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK---EKDEIIFRISAENTVGVSLPTESQS 1956
             YI+E +      W+ I        + CI  +    + +E IFR+   N  GV  P ES+ 
Sbjct: 26636 YIVEKRETSRIMWSII----SEKLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRP 26691

Query: 1957  VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
             V  +     PS P+ P ++ M+  + +   W  P  DGG+ + GY +  R+     W +V
Sbjct: 26692 VIAQNSFVHPSQPSKP-QVTMITRSTMTVVWERPSLDGGSDIDGYYLEKREKKSLQWFKV 26750

Query: 2017  GKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              K  +   +  + +L+E + Y  R+ A N+ G
Sbjct: 26751 IKDPIRDTRQKVHNLTEGNEYQYRVCAINKAG 26782



 Score =  123 bits (297), Expect = 5e-26
 Identities = 92/319 (28%), Positives = 132/319 (41%), Gaps = 9/319 (2%)

Query: 1757  PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815
             PI +K  LD P           +  E  Y+ W     +GG+ I  Y +E ++  +  W  
Sbjct: 24428 PINVKV-LDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSWTV 24486

Query: 1816  XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV 1874
                     + ++ KL     Y FR+ A N+ G   P  S+  +        P  P     
Sbjct: 24487 VEPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESEP-VLAKNPFNKPGPPSTPEA 24545

Query: 1875  SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
             S  T  S+ L W  PE +GGS I  +++E +  +G  WTK      +        + E  
Sbjct: 24546 SAITRDSIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLNDLRFRATGLTEGH 24605

Query: 1935  EIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
                FR+SAEN  GV  P+E         AT P  PP  P ++    S  V  +W  P +D
Sbjct: 24606 FYEFRVSAENAAGVGTPSEPSEYYKACDATYPPGPPNNP-KVTDHSSTTVSLAWSRPIYD 24664

Query: 1994  GGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             GGAP+ GY +  +D+ +  W +      V    F ++ L EN  Y  RI A N  G  E 
Sbjct: 24665 GGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEGAGEH 24724

Query: 2053  LESDEPFKVIPGEGSHADE 2071
             +  D P  VI  E   A E
Sbjct: 24725 V--DVPGSVIAAEKLEAPE 24741



 Score =  122 bits (295), Expect = 8e-26
 Identities = 90/313 (28%), Positives = 132/313 (42%), Gaps = 8/313 (2%)

Query: 1754  ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK- 1812
             E   I+    LD P           + +E   I+W     +GG+ +  Y VE ++  +  
Sbjct: 22260 EKSVIINVKVLDRPGPPDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLV 22319

Query: 1813  WKXXXXXXXXX-ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
             W            +I KL     Y FR+   N+ G   P  SD  I     +TP + P N
Sbjct: 22320 WTVVELKVQTLNLKITKLLPGNEYIFRVIPVNKYGIGEPLESDPVIAANPFVTPEA-PSN 22378

Query: 1872  FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
               VS  T  S+ + W  P ++GGS IT YI+E +  +G  WT+      S     +  + 
Sbjct: 22379 VEVSNITKDSMVITWERPTNDGGSAITGYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLL 22438

Query: 1932  EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
             E     FR+SAEN  GV  P+  +   +       P PP  P ++  V    V+  W  P
Sbjct: 22439 EMRSYEFRVSAENAAGVGKPSPPTVYFKAADPVFKPGPPNNP-KVAYVSRASVVLHWSKP 22497

Query: 1991  EWDGGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
              +DGG  +  Y +   +VT   W M      +   +F  + L E H Y  RI A N+IG+
Sbjct: 22498 IYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGV 22557

Query: 2050  SEPLESDEPFKVI 2062
              E   +D P  VI
Sbjct: 22558 GE--TADIPGSVI 22568



 Score =  119 bits (286), Expect = 1e-24
 Identities = 108/430 (25%), Positives = 181/430 (42%), Gaps = 26/430 (6%)

Query: 1643  YTIEASNTAGTSS---VEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLE 1697
             + + A N  G S    +E ++   D    P  P  + + E+S+  V ++W+ P +DGG  
Sbjct: 13870 FRVAAENAVGPSEFCELEDSVLAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRP 13929

Query: 1698  LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757
             + +Y IEK E    RW+K          Y +  + E  E  F+V A+N  G     E   
Sbjct: 13930 VLRYVIEKKEKLGTRWVKSGKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTD 13989

Query: 1758  IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXX 1816
             IV+      P              + + I W   EKNGGSPII Y +E+ + G +KW   
Sbjct: 13990 IVVIEDPTGPPSPPQELHITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRV 14049

Query: 1817  XXXXXXXARIQK-----LSINTTYQFRIYARNEIGTSLPYT-SDDKITIGKTLTPPS--Q 1868
                     + +      +     Y FR+ A N +G S P   S++   I    +P    Q
Sbjct: 14050 NSRPVKELKYRAGDEEGIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCSPTLDFQ 14109

Query: 1869  PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
              ++ VV E     + +    P     SP   +  +   +K    T       S H   + 
Sbjct: 14110 TKDLVVVEGEKMHLPI----PFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLE-VP 14164

Query: 1929  NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988
             +    D   ++++ EN  G +  T +  V       +P P    +   +  S+  + SW 
Sbjct: 14165 SCLHADAGQYKVTLENRNGATSGTINVKV-----IGLPGPCKDIVASEITKSSCKV-SWE 14218

Query: 1989  TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              P++DGG+P+L Y +  R+  +  +++V   + N L + ++DL +N  Y  R+ A N+IG
Sbjct: 14219 PPDYDGGSPILHYVLQRREAGRRTYVKVMSGE-NKLSWPVKDLIQNGEYYFRVRAVNKIG 14277

Query: 2049  LSEPLESDEP 2058
               E +E   P
Sbjct: 14278 GGEFIELRNP 14287



 Score =  117 bits (282), Expect = 3e-24
 Identities = 111/451 (24%), Positives = 180/451 (39%), Gaps = 26/451 (5%)

Query: 1630  IRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
             +++  L  +H  ++ ++A N  G      +S  +T K   +P  P G + + + ++ S+T
Sbjct: 18120 MKVTNLIPNHDYQFRVKAENEVGLGEPSKASRPITAKDPIEPPGPPGSLKVVDSTKTSIT 18179

Query: 1685  IEWKPPLDDGGLELTKYAIE---KHEPDNNR-------WIKVADVDRDVET-YCIQKLNE 1733
             + W  P+ DGG  +  Y +E   K E +  +       W K     + V T Y I  L+E
Sbjct: 18180 LSWAKPVYDGGAPVIGYLVEMRDKVEMEGEQVRDPEEGWKKCNTSGQLVLTEYTISNLDE 18239

Query: 1734  NCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPS 1791
               EY FRV AQN VG    A   + +  K   + P           +       I  F +
Sbjct: 18240 RQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCPIRLFAT 18299

Query: 1792  EKNGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
              +   +P + +K + +    ++             I + S   + ++ +   N  G    
Sbjct: 18300 IRGRPAPKVTWKRIGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSGEKAV 18359

Query: 1851  YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
             +         K L  P        ++ T  S  L W  PE++GGSPI NYI+E + V  K
Sbjct: 18360 FVRV------KVLDTPGPVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRK 18413

Query: 1911  SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
             +WT   T         I N+    E  FR+ A N  G+ LP +S    L         P 
Sbjct: 18414 TWTN-CTNDLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATDPKSEPDPP 18472

Query: 1971  APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
               +++  +  N     W  P  DGG+ + GY +  +   +          V  L   +  
Sbjct: 18473 KKMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQDGQPEDKWTSYSVVKDLTIVVAG 18532

Query: 2031  LSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             L EN  Y  R+ ARN IG S   E++  F+V
Sbjct: 18533 LKENTKYRFRVAARNAIGCSLAREAEGIFEV 18563



 Score =  115 bits (276), Expect = 2e-23
 Identities = 99/435 (22%), Positives = 175/435 (40%), Gaps = 18/435 (4%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E  + P  +  L+     +G +V  ECQ+ G+P P I WFR+   I+ S DFQ+ Y + 
Sbjct: 736  KEPVVPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITY-EK 794

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--------PLSDHGSEMTVXX 615
            + A L+IRE F ED+G FTC A + AG  S++  L+V+          ++    +  V  
Sbjct: 795  SYARLMIREAFAEDSGRFTCTATSEAGTISTSCYLLVKVSEEIESREEITIQEKQTVVEA 854

Query: 616  XXXXXXXXXXADILEGIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                        +  G P  P F KKP  Q + EG  ++  C++   P+P I W   G  
Sbjct: 855  KDETMSEISSVSVDTGAPAAPFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKSGVP 914

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL----KIKT 729
            +       V+   D    C  L+I+       G YT+ A N+ GE S    L    + + 
Sbjct: 915  LTTGYRYRVSHNKDTG-ECK-LEISMTFADDAGEYTIFAKNQHGETSASTSLLEEEEFEA 972

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
              K+         + +V++ +   +   VV      +   +  +  + + T        I
Sbjct: 973  YMKKQDVTYVTEVTAMVQEPKVADVPPVVVSEYEKELIQRRMAQQTQMMQTFISETEFQI 1032

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            + ++ K +++  +  LK    E + E    + +    E  A    F    +   + E   
Sbjct: 1033 SAIERKIIQEIEIRILKITYQELVIEDGEEMVI-NVAEHEAVASSFSTPVKSYRILEGMG 1091

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            +    ++   P+P I WY++ + I            +    +   V    D G Y   AS
Sbjct: 1092 VTFHCKMGGKPLPKIAWYKDGKRIKHGGRYQMEVLQDGRASLRLPVVLPEDEGIYTAFAS 1151

Query: 910  NSAGKSSHGARVTID 924
            N  G +    ++ ++
Sbjct: 1152 NMKGNAVSSGKLYVE 1166



 Score =  112 bits (269), Expect = 1e-22
 Identities = 78/302 (25%), Positives = 122/302 (40%), Gaps = 7/302 (2%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
             LD P           +D  SV  +W P +K+GG+ +  Y VE +   +  W         
Sbjct: 29462 LDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSESVTR 29521

Query: 1823  XA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                +  +L   T Y FR+ A N  G    +   + +      T P  P    + + +   
Sbjct: 29522 PVFKFTRLVEGTEYVFRVAATNRFGIG-GFLQSEVVECKSVKTVPGAPSTPEILDVSHDG 29580

Query: 1882  VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
             +TL WT PE NGGS I  YIIE K      W  I     ++  +    + E  E  +R++
Sbjct: 29581 MTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPVTMTRYRATGLIEGLEYEYRVT 29640

Query: 1942  AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLL 1999
             A N+ G   P+ +    +        PP  PL  R+  +    V  +W  PE +GGA + 
Sbjct: 29641 AINSRGTGKPSANSKPTIAMDPI--EPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVT 29698

Query: 2000  GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
             GY I ++ V +  W +         ++ +  + +   Y  R+ A N  G  EP E     
Sbjct: 29699 GYLIEMQKVDQVEWTKCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAGEPAEIPGVV 29758

Query: 2060  KV 2061
             KV
Sbjct: 29759 KV 29760



 Score =  111 bits (267), Expect = 2e-22
 Identities = 136/593 (22%), Positives = 229/593 (38%), Gaps = 38/593 (6%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            Q + P F   L+P    +G T+   C V G P  +I W +    +  S + ++ +  D  
Sbjct: 7504 QKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITF-VDGT 7562

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
            ATL +  V   D+G + C A N AG           AP      E+              
Sbjct: 7563 ATLEMTRVSKTDSGDYLCKATNEAGNKPGAPAPAQAAP--SPPQEVKKFDNLFFIEVPKS 7620

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
              I+E    TF  K        G D          P P++ W+ KG+         ++IE
Sbjct: 7621 VHIVEKGTATFIAK-------VGGD----------PIPNVKWM-KGKWRQMTHGGRISIE 7662

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                   + ++I  V K   G Y  VA N+ GE      L +   ++   ++++  K+  
Sbjct: 7663 QKGQE--AKMEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPS 7720

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYT 804
             ++         +V   R  +   +  K  +    T   G   +I  LK +K  + G   
Sbjct: 7721 KQKSPKEEKDIDIVELLR-NVDPKEYEKYARMYGITDFRGLLQAIEFLKKEKELESGRPE 7779

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVP 862
             +    E   + + ++   +   E  EP         Q  TVK++   +   ++   P  
Sbjct: 7780 GEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTVKKEAVFECEIKI-NYPEI 7838

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            +++WY+  + +   +       G+   L I +  +  D G+Y+ V     G     A++T
Sbjct: 7839 TLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTR-DEGNYRIV----CGPHISSAKLT 7893

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRX 981
            +   +V   K +Q     +EG+T  L CQ S   V T+W+ N K +              
Sbjct: 7894 VLEAEVE--KPMQ-DVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEPHSRYTCAVANYT 7950

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G   C  K+ ET+  L ++     F +++Q+  V+E   A  E E++
Sbjct: 7951 QKLSIKDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRIQNIVVREHQSATFECEVS 8010

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
             + A V W +D   +K +  KY F   G    + IRN S  DEG YS I+R E
Sbjct: 8011 FDNAVVTWYKDTWELK-ESPKYTFRSEGRRHFMIIRNVSSADEGVYSVIVRLE 8062



 Score =  109 bits (262), Expect = 8e-22
 Identities = 108/451 (23%), Positives = 199/451 (44%), Gaps = 48/451 (10%)

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            ++P    P +      P+ +  ++     +G + +F+C+V G     ITW+ +   IK S
Sbjct: 3103 EVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLT-ITWYCKDKEIKQS 3161

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEM 611
              F++   D+N   L I  V+PED G +TCVA+N+AG  S +  L V  E  + D+ S+ 
Sbjct: 3162 DIFRVSQFDEN-CQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVDGETEVMDYSSKF 3220

Query: 612  --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
                             D + G  P+F +   +  V  G        +  IP+P+I+W  
Sbjct: 3221 PPQATSSPLTSIKTIQKDAI-GQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFH 3279

Query: 670  KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
              + I P +N  V    D     + L I +      G YT  AVN  GEA+    L +  
Sbjct: 3280 NQQPIKPTKN--VVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAV-- 3335

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
              +E  +V E +++ I  + +                    ++  VK   T+ + +T+S 
Sbjct: 3336 -TEEVTRVREEIEAKIEEEVKEF------------------SSLTVK---TEEEEETYST 3373

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            ++  P+K K     TL+ +  +    +S     E+P  E+   P       E+T+ E  +
Sbjct: 3374 SLHLPEKSK-----TLELKPEQKRFSSSLERKREKPVFESKLTP------AEVTIGE--S 3420

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            ++    V+  P P + W+ N + I+ S   T   + +   L+IT V  + + G+Y C AS
Sbjct: 3421 VRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYE-GEYSCTAS 3479

Query: 910  NSAGKSSHGARVTIDVEKVTFV-KHLQKSYE 939
            N  G+++    + +++ +++   K ++K ++
Sbjct: 3480 NRFGQTTCKTILKVELSQLSAAEKWVEKMFK 3510



 Score =  109 bits (262), Expect = 8e-22
 Identities = 59/203 (29%), Positives = 100/203 (49%), Gaps = 3/203 (1%)

Query: 1861  KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
             K +  P   +N  V ++    +++ W EPES+GGS I  Y++E + VK K+WT       
Sbjct: 12801 KVIDVPGPVKNLQVVDTADGEISIAWEEPESDGGSKILAYVVERRDVKRKTWTLATDCAD 12860

Query: 1921  SVHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVG 1979
             S  E+ +  ++   + +FR+ A N VG     E+ ++V+ +    VP  P   + +  V 
Sbjct: 12861 ST-EYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVPDAPQNVI-VGNVN 12918

Query: 1980  SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
                   SW  P +DGG+ +  Y I +RD T  +W  V     +     I D+ EN  Y+ 
Sbjct: 12919 KFGATVSWEPPLFDGGSEITSYIIELRDRTSVVWAPVMVTKPHERSAIINDVIENKEYIF 12978

Query: 2040  RIYARNEIGLSEPLESDEPFKVI 2062
             R+ A N+ G+ +P  +  P K++
Sbjct: 12979 RVKAENKAGIGKPSAATNPVKIM 13001



 Score =  109 bits (262), Expect = 8e-22
 Identities = 89/290 (30%), Positives = 131/290 (45%), Gaps = 19/290 (6%)

Query: 1779  IDNESVYITWFPSEKNGGSPIIDYKVEIKQ------EGKKW-KXXXXXXXXXARIQKLSI 1831
             I  ES  ++W      GGS + +Y VE+K       E  +W +           +  L  
Sbjct: 15279 IKAESCNLSWDAPLDIGGSELTNYIVEMKDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVT 15338

Query: 1832  NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
                Y+FR+ A N+ G S    +++ + I      P  P    ++E +   + L W  P+ 
Sbjct: 15339 GGNYKFRVKAENKYGISEACETEE-VEIKDPSALPGPPEKVTIAERSKTHMLLTWEPPKD 15397

Query: 1892  NGGSPITNYIIEFKTVKGKS-WTKIVTV-----GGSVHEHCIENIKEKDEIIFRISAENT 1945
             +GGS IT Y +E K  KG S W+++  +     G    E+ +  + E  E  FR  A N+
Sbjct: 15398 SGGSMITGYWLE-KREKGTSYWSRVNKILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNS 15456

Query: 1946  VGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
              G+  P+  S+S   +   T PS P AP EI     + V  +W  P  DGG P+ GY I 
Sbjct: 15457 AGIGPPSAISESAVADDPLTPPSMPAAP-EIADKTKHSVTLAWTPPAKDGGRPIKGYIIE 15515

Query: 2005  IRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             I+D   + W  V   +    +  F I +L E   Y  RI A NEIG SEP
Sbjct: 15516 IQDEGTSEWARVNDAENLHPSTVFTIPNLPELKKYRFRIIAVNEIGESEP 15565



 Score =  109 bits (261), Expect = 1e-21
 Identities = 101/439 (23%), Positives = 184/439 (41%), Gaps = 26/439 (5%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGP---VIMREISRESVTI 1685
             R+ ++      ++ + A N AG    S    + V + P+ P  P   + + E +R+ + I
Sbjct: 13959 RVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIEDPTGPPSPPQELHITEAARDHICI 14018

Query: 1686  EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC-----EYMFR 1740
              WK P  +GG  +  Y IE  E    +W++V    R V+    +  +E       EY FR
Sbjct: 14019 AWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNS--RPVKELKYRAGDEEGIVPEKEYTFR 14076

Query: 1741  VIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             V A N VG SE  +    V     D  P+          ++ E +++   P        I
Sbjct: 14077 VRAVNSVGASEPSDISENVFAIDSDCSPTLDFQTKDLVVVEGEKMHLP-IPFRAVPSPKI 14135

Query: 1800  IDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
               +K   E+K + + +            +         Q+++   N  G +        I
Sbjct: 14136 TWHKDGNEMKADDRTF-FRAEYTSCHLEVPSCLHADAGQYKVTLENRNGAT-----SGTI 14189

Query: 1858  TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
              + K +  P   ++ V SE T  S  + W  P+ +GGSPI +Y+++ +    +++ K+++
Sbjct: 14190 NV-KVIGLPGPCKDIVASEITKSSCKVSWEPPDYDGGSPILHYVLQRREAGRRTYVKVMS 14248

Query: 1918  VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIR 1976
              G +     ++++ +  E  FR+ A N +G     E ++ V  E     P PP   +E  
Sbjct: 14249 -GENKLSWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPP-VDVETH 14306

Query: 1977  MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
                S  V  +W  P +DGG+ ++GY +      +  +       V  L + ++ L+    
Sbjct: 14307 NPTSESVTLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKGLTHEKQ 14366

Query: 2037  YMIRIYARNEIGLSEPLES 2055
             Y  R+ A N  G+S+P  S
Sbjct: 14367 YQFRVRAENAAGVSDPSRS 14385



 Score =  108 bits (259), Expect = 2e-21
 Identities = 137/586 (23%), Positives = 236/586 (40%), Gaps = 65/586 (11%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            +K  K   V E      EC +     P   WL  G EI   E   + ++  +H     LK
Sbjct: 2658 TKPLKNLEVPETHVATFECEVSHFNVPS-TWLKNGVEIEMSEKFRIVVQGKLHQ----LK 2712

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            I N  +     YT V  N +  A+L +          P  +   LK +  ++ +++    
Sbjct: 2713 IMNTSRDDSAEYTFVCGNDKVSATLTV---------SPVLITSMLKDLNAQEKDTITFEV 2763

Query: 757  QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
              V     T  W KN   +++     T++   +HS+TI +     D G Y   A    G 
Sbjct: 2764 -TVNYEGITYKWLKNGVEIRSSDRCQTRTKQLSHSLTI-RNVHFGDVGDYKFVA----GS 2817

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            AET+A + VE    E      F    ++I V EK        ++  P   +TW ++ + +
Sbjct: 2818 AETAAKLFVEARVIE------FTKHIKDIKVTEKKKAVFECELSE-PNVQVTWMKDGQEL 2870

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
              SE    + +     L+I  V    D+G+Y  VA +S  K    A +T++ + V   + 
Sbjct: 2871 ELSERYKVSTERHVHRLMIQTVRMS-DAGEYSVVAGSSVSK----ANLTVEGKDVRISEP 2925

Query: 934  LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS-GMDHR---EIIQEGRXXXXXXXX 988
             +K     E +    E + +   +  +W  N  EI   +D R    II+  +        
Sbjct: 2926 AEKEITVLEKQRSTFEFEVNEDDIEGRWLRNGVEIQFSVDQRFNYAIIR--KIHRLTITE 2983

Query: 989  XXXXDVGVIKCIV-KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETAD 1046
                D G    I  K++   T+ V     P+ IR +Q   V+    A   VE+       
Sbjct: 2984 TYRSDAGEYTFIAGKNRSIVTLHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQ 3043

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEV 1100
            V W ++ + +     K  F + G+   L +      D  +Y+C  +++      S +  V
Sbjct: 3044 VSWYKNSQALS-SGFKCKFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNV 3102

Query: 1101 TVVEL----------PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150
             V E+          PP ++T +QN   N+G  A F+  ++  D  + W+    EI+ S+
Sbjct: 3103 EVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDKEIKQSD 3162

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVE 1192
              +++   +  +L+I     +D GEY+C   NS     C+A+L V+
Sbjct: 3163 IFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVD 3208



 Score =  107 bits (257), Expect = 3e-21
 Identities = 86/319 (26%), Positives = 136/319 (42%), Gaps = 13/319 (4%)

Query: 1739  FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
             + + A NP GF++ + +  +     LD P           +  E   ++W P   +GG  
Sbjct: 21168 YTLTASNPGGFAKFVFNVKV-----LDRPGPPEGPLHVTDMTVEKCVLSWLPPLHDGGGK 21222

Query: 1799  IIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
             I  Y ++ ++  +  W            ++ KL     Y FR+ A N+ G   P  S+  
Sbjct: 21223 IEYYIIQRRETSRLTWTNVATDLQVNRYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPA 21282

Query: 1857  ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
             +     + P   P+   V+  T  S+ + W  PE NGGS I  YIIE +   G  W K  
Sbjct: 21283 VATNPYV-PSDPPQAPEVTAITKDSMVVCWGHPEYNGGSSINTYIIERRDKTGLRWVKCN 21341

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV--PSPPTAPLE 1974
                 +     +  +    E  +RI AEN  G+S P+ S S   +   T+  P PP  P  
Sbjct: 21342 KRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPS-SPFYKACDTIFQPGPPGNPRV 21400

Query: 1975  IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV-DVNTLKFNIRDLSE 2033
             +    S+I + +W  P +DGG+ + GY +      +  W  V  +  +    F I +L+E
Sbjct: 21401 LDTTKSSITI-AWNKPVYDGGSDITGYIVETCLPEEDEWTIVTPMAGLTATSFTITNLTE 21459

Query: 2034  NHTYMIRIYARNEIGLSEP 2052
             N  Y I I A N  G+ EP
Sbjct: 21460 NQEYKINISALNCEGVGEP 21478



 Score =  103 bits (247), Expect = 5e-20
 Identities = 96/379 (25%), Positives = 158/379 (41%), Gaps = 23/379 (6%)

Query: 523   DGSTVQFECQVEGYPR-PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
             +G  V+F C +E Y R  ++TW+  +  +  S  +++ Y +  VA++ ++++   D G +
Sbjct: 31213 EGGHVRFVCCIENYDRNTEVTWYFGSRKLTASHKYEITYAN-GVASIYVKDIEECDDGLY 31271

Query: 582   TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
              C   +     ++  EL VE   S     +              + IL+  PP F+    
Sbjct: 31272 RCKVVSEDREDNAYAELFVETVRSFREYYLG-RSLKKPRRRIDKSKILQR-PPEFTLPLF 31329

Query: 642   AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
              +    G D+     +   PEP + WL  G  I PD        SD  +Y   L I NV 
Sbjct: 31330 NRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPK-KYTFTSDKGLY--QLMIHNVD 31386

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR----QGESVILSAQ 757
                +  YTVVA N+ GE S    L +         +    K ++      +G+SV    +
Sbjct: 31387 LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLR 31446

Query: 758   VVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             V G P PT+ W KN KP++  P     + D D + I  ++   ++D G Y + A N+ G 
Sbjct: 31447 VSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVD-YFILHIRETLIEDSGTYRVTATNTAGS 31505

Query: 814   AETSAVITVEEPT------EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             A   A + VE  T      +   E  +++    E T+K          V  NPV      
Sbjct: 31506 ASCQATLKVERLTYTRREFKSEEERHIYVRNQIEKTLKMAQEFSKAEVVALNPVAQEALK 31565

Query: 868   RNNEIISPSETITQNFDGE 886
                E+  P+ + T++  GE
Sbjct: 31566 EAAELYKPAVS-TKHVQGE 31583



 Score =  103 bits (246), Expect = 7e-20
 Identities = 106/426 (24%), Positives = 174/426 (40%), Gaps = 28/426 (6%)

Query: 1663  YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             ++KP  P  P     I+R+S+ + W+ P DDGG ++  + +EK + +  RW K      +
Sbjct: 24534 FNKPGPPSTPEASA-ITRDSIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLN 24592

Query: 1723  VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
                +    L E   Y FRV A+N  G      SEP     A D              D+ 
Sbjct: 24593 DLRFRATGLTEGHFYEFRVSAENAAGVGTP--SEPSEYYKACDATYPPGPPNNPKVTDHS 24650

Query: 1783  S--VYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR---IQKLSINTTYQ 1836
             S  V + W     +GG+P+  Y VE K   + +W          A    ++KL  N  Y 
Sbjct: 24651 STTVSLAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYN 24710

Query: 1837  FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             FRI A N  G          +   + L  P    +  + +  +   +       +  G P
Sbjct: 24711 FRICAVNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFVTIRGRP 24770

Query: 1897  ITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
                  +++K   G    +  + V GS     I+N+   D   + ++ EN +G    ++S 
Sbjct: 24771 EPE--VKWKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLTLENNIG----SKSA 24824

Query: 1956  SVRLEKHATVPSPPTAPL--EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
              V ++    V   P+AP+  E++ V  + V   W  P+ DGGA +  Y +  R+  +  +
Sbjct: 24825 FVNVK----VLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAKITHYIVEKRESKRLAF 24880

Query: 2014  MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
               +    V      + DL E   Y  R+ A NE+G+  P E+ E  K+     S A   P
Sbjct: 24881 TSITNNCVRN-SIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKI-----SQAPLPP 24934

Query: 2074  GEQTEV 2079
             G+ T +
Sbjct: 24935 GKITVI 24940



 Score =  101 bits (243), Expect = 2e-19
 Identities = 112/381 (29%), Positives = 162/381 (42%), Gaps = 75/381 (19%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568
            P  +  ++P     G   +F  +V G P+PQ++W++ +  +  S  F+  +  + N  TL
Sbjct: 3013 PQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQAL--SSGFKCKFLREGNEHTL 3070

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXX 625
            ++ EVFPEDA  + C AKN  G A+S+  L VE P     D G+ ++             
Sbjct: 3071 LLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLS------------- 3117

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
                   PP      +    +EG     +CR V+  +  I W  K +EI   +   V   
Sbjct: 3118 -------PPVVLTPIQNTSANEGQSARFQCR-VSGEDLTITWYCKDKEIKQSDIFRV--- 3166

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------PPQV 737
            S     C  L+IT V    EG YT VA N  G  S   +LK+  GE E        PPQ 
Sbjct: 3167 SQFDENCQ-LEITRVYPEDEGEYTCVARNSAGMVSCSALLKV-DGETEVMDYSSKFPPQA 3224

Query: 738  ----------------------IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
                                   +P+ S +V  GE     A V G P+P I+W  N +P+
Sbjct: 3225 TSSPLTSIKTIQKDAIGQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFHNQQPI 3284

Query: 776  KALPTKS-----DGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITV-EEPT-- 826
            K  PTK+     D  T++ T++      +  G YT KA N  G A  SA + V EE T  
Sbjct: 3285 K--PTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAVTEEVTRV 3342

Query: 827  --EENAEPPLFINRFQEITVK 845
              E  A+    +  F  +TVK
Sbjct: 3343 REEIEAKIEEEVKEFSSLTVK 3363



 Score =  100 bits (239), Expect = 5e-19
 Identities = 69/231 (29%), Positives = 115/231 (49%), Gaps = 17/231 (7%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTK--SDGDTHS 788
           + P   +PL+S++  +G +    AQV GNP P ++W ++ + + A  LP    S  D  +
Sbjct: 4   QAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRA 63

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
           + ++        G ++++A N  G A ++A + V   T E A PP FI R Q +TV++  
Sbjct: 64  VLMIPAVTAAHSGRFSVRATNGAGQATSTAELLV---TAETA-PPNFIQRLQSLTVRQGS 119

Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            ++L  RVT  P P + +YR    I  S       DG+   L+I     E DSG Y   A
Sbjct: 120 QVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPE-DSGTYSVSA 178

Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959
           SNS+G+++  A + +  E        +++   ++ KT+I   Q S T  T+
Sbjct: 179 SNSSGRATSTAELLVQGE--------EEAVPAKKSKTIISASQISQTRQTR 221



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 155/752 (20%), Positives = 268/752 (35%), Gaps = 48/752 (6%)

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             S T+K + +     +++R EN  G +D   +  ++       +P +    S    +    
Sbjct: 14355 SYTVKGLTHEKQYQFRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKR 14414

Query: 1404  PE----NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
              E    +   S   Y  + +   + T W       + +  I+  K     +       E 
Sbjct: 14415 GEEIRLDANISGFPYPQITWMRNNATIWPEPLK-KRPERPIKKKKEKEEKKEEGAEKKEA 14473

Query: 1460  DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
             D     E  E  +  KE K +    EK  +    EP E             P+  ++   
Sbjct: 14474 DAEKKEEDKEAKEEDKEKKEEKKEEEKEKEKEVEEPEE-------------PEEEYHPSL 14520

Query: 1520  KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISN 1577
              +  T ++  +                 +     NDHG    SC V I   P   +    
Sbjct: 14521 NERLTIESKRKGESYIIIKDTIRGDHGVFTIKVENDHGTASASCEVNILDTPGPPVNFKF 14580

Query: 1578  EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
             E+I+ K+ +  +W       G      I  +  N         +T+  +     + +L  
Sbjct: 14581 EEIR-KNSILCKWDPPLDDGGSEILNYILERKDNSKAELGWITVTSILRGCKFLVPKLIE 14639

Query: 1638  SHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
                  + + A N  G     +T  V     +D P  PE P I ++++  S+ + W  P +
Sbjct: 14640 GKEYLFRVTAENKYGPGKPCITKPVIARNPFDPPDAPEKPEI-KDVTASSMCVTWLEP-N 14697

Query: 1693  DGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             D G  +  Y +EK E ++  W +V   +  D+E   ++ L E   Y+FRV A+N  G  +
Sbjct: 14698 DNGSAIEGYWVEKREINSTHWARVNRTMVPDLEIN-VEGLLEGLTYIFRVCAENIAGPGK 14756

Query: 1752  ALESEPIVIKTALDVPSXXXXXXXXXXIDNE--SVYITWFPSEKNGGSPIIDYKVEIKQE 1809
                S P   KTA   P           +D    S+ I W P   NGG+ +  Y V+    
Sbjct: 14757 F--SPPSEPKTA-QAPIMPPGPPIPRIVDTSDYSIDIEWDPPADNGGAEVFGYHVDKLVA 14813

Query: 1810  GKK-WKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
             G K W                 +     Y  R+ A N  G   P  +D  I       P 
Sbjct: 14814 GTKDWSRATERPHKTRTFTVYGVREGAKYIVRVVAINCAGEGEPGLTDAVIVRNPAEVPV 14873

Query: 1867  SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
              +    V +    R+  +        G  P +    +      K   ++   G       
Sbjct: 14874 IELDISVRNGVVVRAGEMLRIPAHVTGRPPPSLKWTKDDGDLEKDRMEVEEAGQD-STVV 14932

Query: 1927  IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
             I+  K  D   ++I A N  G+    +S   R+E    VP P    L+  +V   ++M +
Sbjct: 14933 IKTTKRSDHGKYQIQAANPSGI----KSAWTRVEV-MDVPGP-VLDLKPVVVTRKLMMLN 14986

Query: 1987  WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
             W  P+ DGG+ + G+ I  R+     W +   ++  + K  I  + E   Y+ R+ A+N+
Sbjct: 14987 WSDPDDDGGSDVTGFIIERREPKMHTWRQ--PIETPSSKCEIVGIIEGQEYIFRVVAKNK 15044

Query: 2047  IGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078
              G   P++   P + +  +G     E    TE
Sbjct: 15045 YGCGPPVDLG-PIRAVDPQGPPTSPEKFHYTE 15075



 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 12/184 (6%)

Query: 1298  RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSID--SKSASLTIKKVE 1351
             R+++   + +  +    P P  EW+ +  +I+K           ID  +    L+I  V 
Sbjct: 15179 RVRKNEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVT 15238

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
               D G Y +   N  G     + V +LD+P+PP    +  I + S N+ WD P + G S 
Sbjct: 15239 RLDKGTYTVTASNRLGTLSHSVTVEVLDRPTPPRNVAVSSIKAESCNLSWDAPLDIGGSE 15298

Query: 1412  IIYYVVEYQEI-----DTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             +  Y+VE +++     +  EW+ V K+I + +  + NL T  +Y+FR  A N+  IS+A 
Sbjct: 15299 LTNYIVEMKDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVTGGNYKFRVKAENKYGISEAC 15358

Query: 1466  ETTE 1469
             ET E
Sbjct: 15359 ETEE 15362



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 8/202 (3%)

Query: 725   LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTK 781
             +K K    E P + E +K    + GES IL+ Q++G P P I W +  K +   +     
Sbjct: 30156 IKTKLSVGEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMS 30215

Query: 782   SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
             SDG  HS++++  ++ +DEG+YT +A N  G  ETS  + ++   + +   PL    +  
Sbjct: 30216 SDGRNHSLSVMTDEQ-EDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAG 30274

Query: 842   ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
                  +  +  + R    P+P I W+   + ++PSE +          LVI NV  + ++
Sbjct: 30275 CGTSLRLHVVYIGR----PIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNA 30330

Query: 902   GDYKCVASNSAGKSSHGARVTI 923
             G YK   SN  G      RV I
Sbjct: 30331 GRYKVQLSNKFGTVDTVLRVEI 30352



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 95/367 (25%), Positives = 153/367 (41%), Gaps = 33/367 (8%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            +E +++A  F   ++     +G  V F C++ G P P+I W++    IK    +QM    
Sbjct: 1068 AEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWYKDGKRIKHGGRYQMEVLQ 1127

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH----GSEMTVXXXXX 618
            D  A+L +  V PED G +T  A N  G A S+ +L VE+  +       +E        
Sbjct: 1128 DGRASLRLPVVLPEDEGIYTAFASNMKGNAVSSGKLYVESTAAAQPYYPQAEAVRRVQST 1187

Query: 619  XXXXXXXADILEGIPPTFS-KKPKAQYVDEGSDILLE--CRLVAIPEPDIAWLFKGEEIV 675
                   A    G  P  S  +  A+ +D+  +  LE   + V + +P      +G+   
Sbjct: 1188 SPMSARSASYSPGRSPARSVSRSPARRLDDTDESQLERLYKPVFVQKPSSFRCSEGQTAR 1247

Query: 676  PDENISVAIESDMHMYCSVLKITN-----VKKFQEGTYTVVAV---------------NR 715
             D  +      D   + S  ++ N     +   ++GT +++ V               NR
Sbjct: 1248 FDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNR 1307

Query: 716  EGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN-- 772
             G+ ++ + L ++  E    PQ IE LK++ V++G  V L+ + +GNP P I W KN+  
Sbjct: 1308 AGKTTVSMTLTVEAKENLVRPQFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWLKNSDI 1367

Query: 773  -KPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSAVITVE-EPTEEN 829
              P K    K +G         P+    D   YT  A N  G   T   + VE E TE  
Sbjct: 1368 ISPHKYPHIKIEGAKGQAHFQIPQTSGSDSAWYTATAINKAGRDTTRCRVNVEVEYTEPV 1427

Query: 830  AEPPLFI 836
             E  L I
Sbjct: 1428 PERRLII 1434



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 59/198 (29%), Positives = 94/198 (47%), Gaps = 10/198 (5%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSI 789
            P  ++   S    +G++     +VVG P P   W  + + V       +  K DG T S+
Sbjct: 1229 PVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDG-TQSM 1287

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
             ++ P   +D G +T+ A+N  G    S  +TVE   +EN   P FI + + I+VKE   
Sbjct: 1288 IVV-PAMPQDSGEWTVVAQNRAGKTTVSMTLTVE--AKENLVRPQFIEKLKNISVKEGSL 1344

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI-TNVDSEIDSGDYKCVA 908
            ++L  +   NP+P I W +N++IISP +      +G   +        S  DS  Y   A
Sbjct: 1345 VELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGSDSAWYTATA 1404

Query: 909  SNSAGKSSHGARVTIDVE 926
             N AG+ +   RV ++VE
Sbjct: 1405 INKAGRDTTRCRVNVEVE 1422



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 5/170 (2%)

Query: 1300  KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGI 1357
             K G+ + L  D    P+P  +W     ++K     + +ID+K   ++L+I K +  D   
Sbjct: 13418 KAGTKIELPADITGKPEPKVKWTKADLVLKP--DDRITIDTKPGHSTLSIAKTKRDDTAT 13475

Query: 1358  YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             Y +   N+ G A   ++V ILDKP PP   +I EI + S  + W+ P + G S +  Y+V
Sbjct: 13476 YIIEAVNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNYIV 13535

Query: 1418  EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             E + +D+  W  + +  K  T     L     Y FR YA N+  I   +E
Sbjct: 13536 ERKAVDSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVYAENQFGIGAPAE 13585



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 61/232 (26%), Positives = 99/232 (42%), Gaps = 9/232 (3%)

Query: 1240  EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK-----VEVVE--FPPKIVD 1292
             +K+T  S VK  T+++    E+ +  +     +A   +  +      EV E    PKI+ 
Sbjct: 18515 DKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIV 18574

Query: 1293  YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
              +     + GS + +       P P  +W   S  I             ++ L +K V  
Sbjct: 18575 SD-VVTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPTTSLLMVKDVTR 18633

Query: 1353  TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411
              D+G Y L  EN+    +  + + I+D P PP  P  ILE+D  +  + WD P   G S 
Sbjct: 18634 KDSGYYSLSAENSTAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSN 18693

Query: 1412  IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
             I  Y+VE  ++   +W++  + TKT   +  L     Y FR  A N   IS+
Sbjct: 18694 ITNYIVEKCDVTRGDWVTAVSCTKTSCRVGKLTCGKEYGFRVRAENRFGISE 18745



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 20/249 (8%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTS---EEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
            +E  Y+  L      K  +L   +K  S   E +   P+F  KL P     G +V+F   
Sbjct: 3367 EEETYSTSLHLPEKSKTLELKPEQKRFSSSLERKREKPVFESKLTPAEVTIGESVRFTVT 3426

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
            V G+P+P++ WF     I  S  +    + D  + L+I +V  +  G ++C A N   F 
Sbjct: 3427 VSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYS-LIITKVKKDYEGEYSCTASNR--FG 3483

Query: 593  SSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
             +T + I++  LS    +E  V               + G PP F+ + +     EGS++
Sbjct: 3484 QTTCKTILKVELSQLSAAEKWVEKMFK----------IPGQPPCFTTQIQPVQCVEGSEV 3533

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
              + ++   P PD+ W     +I   +  SV    D   +   L ++N+++   G YT  
Sbjct: 3534 KFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGF---LIMSNIQQRDSGLYTCK 3590

Query: 712  AVNREGEAS 720
            AVN  GEAS
Sbjct: 3591 AVNPFGEAS 3599



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 11/203 (5%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
           PTF++  ++    EGS    E ++   P P+++W   G+ +         I  SD     
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGR--- 62

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           +VL I  V     G ++V A N  G+A+    L + T E  PP  I+ L+S+ VRQG  V
Sbjct: 63  AVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLV-TAETAPPNFIQRLQSLTVRQGSQV 121

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  +V G P P + + +    +++        DGD +S+ I +    +D G Y++ A N
Sbjct: 122 RLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFP-EDSGTYSVSASN 180

Query: 810 SEGIAETSAVITVEEPTEENAEP 832
           S G A ++A + V+   EE A P
Sbjct: 181 SSGRATSTAELLVQ--GEEEAVP 201



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 93/417 (22%), Positives = 168/417 (40%), Gaps = 29/417 (6%)

Query: 1700  KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758
             +Y +E  + ++  W + +     V+   +  L E  EY FRVIA N  G  + +  +E +
Sbjct: 19845 RYYVEFKDRNSLMWKRASKTQLRVKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTESL 19904

Query: 1759  VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXX 1817
             V    +D P           +   SV + W   + +GG  +  Y VE ++  GK W    
Sbjct: 19905 VALDPIDPPG----KPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMKAN 19960

Query: 1818  XXXXXXA--RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVV 1874
                       +  L    T +FRI A+N  G  S P  + + +       PP+   +  +
Sbjct: 19961 HVNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEM 20020

Query: 1875  SESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH--CIENI 1930
              +  +     T+  T     G  P T   +  K  +    + IV +  +       I+  
Sbjct: 20021 KDGVTVKAGGTIVITASSILGKPPPT--AVWSKAGREFKSSDIVQISSTPTSSTLSIKYA 20078

Query: 1931  KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
               K+   + I+A N  G+    + + V++ K   VP PP  P+E   V +     +W  P
Sbjct: 20079 SRKNTGEYTITASNPFGI----KDEKVKV-KVLDVPGPP-GPIEASSVSAEKCTLTWLPP 20132

Query: 1991  EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
             E DGG  +  Y +  R+ ++ +W ++ + +V   ++    L + + Y+ R+ A N+ G  
Sbjct: 20133 EEDGGCSIKSYILEKRETSRLLWTKLAE-NVMDCRYVASKLIKGNEYIFRVSAVNQYGTG 20191

Query: 2051  EPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREH-NMDADIRSY 2106
             +  +S  P K++   G      PG  ++              W R   +  +DIR Y
Sbjct: 20192 DVTQSG-PVKMVDSFG-----PPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGY 20242



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 66/236 (27%), Positives = 106/236 (44%), Gaps = 21/236 (8%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTH 787
            ++E P     L    V  GESV  +  V G P+P + W  N K + +    +   + D +
Sbjct: 3400 KREKPVFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEY 3459

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE------------PPLF 835
            S+ I K KK   EG Y+  A N  G      ++ VE      AE            PP F
Sbjct: 3460 SLIITKVKK-DYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCF 3518

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVIT 893
              + Q +   E   +K   +VT  P P + W++ N  I  S+T  +  N DG    L+++
Sbjct: 3519 TTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGF-LIMS 3577

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            N+    DSG Y C A N  G++S  A + +  ++V+ V H Q+  + ++   V ++
Sbjct: 3578 NIQQR-DSGLYTCKAVNPFGEASCSAELIVFHKQVS-VFHKQQLVQEQKSYKVSMK 3631



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 58/215 (26%), Positives = 98/215 (45%), Gaps = 7/215 (3%)

Query: 1291  VDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
             +D++ ++  +  G  + L + ++A P P   W  +   +K    T    +  S  L +  
Sbjct: 14106 LDFQTKDLVVVEGEKMHLPIPFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLEVPS 14165

Query: 1350  VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
               + DAG YK+ LEN  G     +NV ++  P P       EI  SS  + W+ P+  G 
Sbjct: 14166 CLHADAGQYKVTLENRNGATSGTINVKVIGLPGPCKDIVASEITKSSCKVSWEPPDYDGG 14225

Query: 1410  STIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             S I++YV++ +E     ++ V     K    +++L  N  Y FR  AVN++   +  E  
Sbjct: 14226 SPILHYVLQRREAGRRTYVKVMSGENKLSWPVKDLIQNGEYYFRVRAVNKIGGGEFIELR 14285

Query: 1469  EYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELT 1502
                 VI E + Q P  + P+   T  P +E + LT
Sbjct: 14286 N--PVIAEDQKQRP--DPPVDVETHNPTSESVTLT 14316



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 60/249 (24%), Positives = 114/249 (45%), Gaps = 19/249 (7%)

Query: 732   KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTH 787
             + PP+   PL +     GE V     +  +P P++TW K    +K  P K    SD   +
Sbjct: 31319 QRPPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPKKYTFTSDKGLY 31378

Query: 788   SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKE 846
              + I     + D+  YT+ A N  G     A + V      E+   P+F      I   E
Sbjct: 31379 QLMIHNVD-LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVE 31437

Query: 847   KGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEI--DSG 902
               +++   RV+  P P++ W +N + +   P   + Q    E+++  I ++   +  DSG
Sbjct: 31438 GQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQ----EDVDYFILHIRETLIEDSG 31493

Query: 903   DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH 962
              Y+  A+N+AG +S   + T+ VE++T+ +   + +++EE + + +  Q   T+      
Sbjct: 31494 TYRVTATNTAGSAS--CQATLKVERLTYTR---REFKSEEERHIYVRNQIEKTLKMAQEF 31548

Query: 963   NKKEISGMD 971
             +K E+  ++
Sbjct: 31549 SKAEVVALN 31557



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 102/481 (21%), Positives = 195/481 (40%), Gaps = 35/481 (7%)

Query: 1010  LVVKETIPEFI--RKLQDFEVKEKDVAI-LEVEINSETA-DVVWERDGEIIKPKKNKYDF 1065
             LV +E +P+F    +L+   V +   +I + V I    A +VVW ++     P K +   
Sbjct: 20403 LVDREEVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAPEVVWYKENV---PLKGRAHI 20459

Query: 1066  EKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQNQKVNKG 1121
             +       + I   + +D G+Y   L +    ++    V VV+ P   +     +     
Sbjct: 20460 DTTESYTLVVIPECTRYDAGKYVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHS 20519

Query: 1122  NKATFEIELTKGDALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
                 +EI L  G + ++ +  +  E     +  +T + +K   KI D  L++A EY   V
Sbjct: 20520 ITLQWEIPLIDGGSKIKNYIIEKREATRKAYSVITTNWQKCSYKIPD--LEEAAEYYFRV 20577

Query: 1181  GNSKCTAI-LTVEEPSINFTLRLP----EFILVPANTD-AYLTVEIP--DETLDVTWYKK 1232
                    I    E P      + P    + I+   + D A L    P  D    +T Y  
Sbjct: 20578 SAENEMGIGEPAETPDPIRASQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVI 20637

Query: 1233  KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT----------KLKVE 1282
             ++ ++D++++  ++ +K    I  +  E+ +  +    +++   +          K +  
Sbjct: 20638 EAQLKDSDQWAHVTTIKALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTT 20697

Query: 1283  VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
               EF  + + Y++    K G ++ + +     P+P   W    + +K+ +       + S
Sbjct: 20698 APEFDLRSI-YQKTVVAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASS 20756

Query: 1343  ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
               L I +++  D G Y +  +N  G     + V + D P PP  P  + E+    + I W
Sbjct: 20757 TILNINEIKRKDGGQYSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDYVLISW 20816

Query: 1402  DEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
             + PEN G   I  Y+VE +E   T W+ +   + +T      L T   Y+FR  A N   
Sbjct: 20817 EAPENDGGVPINNYIVEMRETTGTSWMELAATVIRTTFKAARLTTGIEYQFRVKAQNRYG 20876

Query: 1461  I 1461
             +
Sbjct: 20877 V 20877



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 37/96 (38%), Positives = 63/96 (65%), Gaps = 1/96 (1%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           ++  P F+++L+      GS V+ + +V G P P + ++R+ A I+ S DFQ+  D D +
Sbjct: 100 ETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGD-L 158

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +L+I E FPED+GT++  A N++G A+ST EL+V+
Sbjct: 159 YSLLIAEAFPEDSGTYSVSASNSSGRATSTAELLVQ 194



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 74/313 (23%), Positives = 134/313 (42%), Gaps = 24/313 (7%)

Query: 1171  DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTW 1229
             +D GE S  V  S       +++P ++  ++    I+V A     L   +  +    VTW
Sbjct: 17847 NDGGE-SAWVSTSDIVVKEEIQKPVLD--MKFVGTIVVKAGESVRLEAGLRGKPQPTVTW 17903

Query: 1230  YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFP 1287
              K K+   D  + ++ +       ++ K    D  +Y     +     T    V V++ P
Sbjct: 17904 VKDKAT-GDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVTVLDIP 17962

Query: 1288  PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT- 1346
               +    R+ +I   S     V +   P+ +    V+S II+KC+  +    + SASL  
Sbjct: 17963 GPV----RDMKISGISTDKCRVAWDP-PEDDGGCEVDSYIIEKCETRRMVWSTYSASLVT 18017

Query: 1347  ----IKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
                 + ++   +  I+++R EN  G      +  I+ K     P PP  P + +I    +
Sbjct: 18018 NYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPIIAKTQYNRPGPPDAPEVTKIGKDEM 18077

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
              + W  PEN G  +I  Y++E +E     W+ V    I++ +  + NL  N  Y+FR  A
Sbjct: 18078 TVVWAPPENDGGKSITGYILERKEKRAVRWVPVTKSPISERRMKVTNLIPNHDYQFRVKA 18137

Query: 1456  VNEVDISDASETT 1468
              NEV + + S+ +
Sbjct: 18138 ENEVGLGEPSKAS 18150



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 136/624 (21%), Positives = 243/624 (38%), Gaps = 94/624 (15%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP   +  +   V+ G        +  IP+P ++W    + +          E + H   
Sbjct: 3012 PPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLREGNEHTLL 3071

Query: 693  SV-LKITNVKKFQ---EGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
             + +   +  ++    +  Y V   +      +P V+   TG    PP V+ P+++    
Sbjct: 3072 LIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLTPIQNTSAN 3131

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTL 805
            +G+S     +V G    TITW   +K +K   +   S  D +    +     +DEG YT 
Sbjct: 3132 EGQSARFQCRVSGEDL-TITWYCKDKEIKQSDIFRVSQFDENCQLEITRVYPEDEGEYTC 3190

Query: 806  KAENSEGIAETSAVITVEEPTE-----------ENAEPPLFINRFQEITVKEKGTI---- 850
             A NS G+   SA++ V+  TE             + P   I   Q+  + +K +     
Sbjct: 3191 VARNSAGMVSCSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTIQKDAIGQKPSFFQPI 3250

Query: 851  -----------KLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDS 897
                       +  A V+  P P I+W+ N + I P++ +  +FD       L+I +  S
Sbjct: 3251 MSSVVAHGEVARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFS 3310

Query: 898  EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957
            E  +G Y C A N  G+++  A + +  E+VT V+   ++   EE K       +S TV 
Sbjct: 3311 E-HAGQYTCKAVNIRGEAACSANLAV-TEEVTRVREEIEAKIEEEVKEF-----SSLTVK 3363

Query: 958  TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP 1017
            T+    ++E +      + ++ +                ++   + +  S+ L  K   P
Sbjct: 3364 TE----EEEETYSTSLHLPEKSK---------------TLELKPEQKRFSSSLERKREKP 3404

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             F  KL   EV   +     V ++      V W  +G+ I    + Y F +      L I
Sbjct: 3405 VFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAI-TSSSIYTFVEERDEYSLII 3463

Query: 1077 RNTSVHDEGEYSCILRD---ESCTAEVTVVEL-------------------PPEIITRLQ 1114
                   EGEYSC   +   ++    +  VEL                   PP   T++Q
Sbjct: 3464 TKVKKDYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQ 3523

Query: 1115 NQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY-DCDLD 1171
              +  +G++  F+ ++T G     V+WFK  S+I+ S    +  +       I  +    
Sbjct: 3524 PVQCVEGSEVKFQYKVT-GTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQR 3582

Query: 1172 DAGEYSCEV----GNSKCTAILTV 1191
            D+G Y+C+     G + C+A L V
Sbjct: 3583 DSGLYTCKAVNPFGEASCSAELIV 3606



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 78/346 (22%), Positives = 137/346 (39%), Gaps = 17/346 (4%)

Query: 1192  EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250
             E P I+    L + + V A     L   I       VTW  K+  +++  +   +  +  
Sbjct: 18272 EHPEIDLDASLRKGLSVRAGCPIRLFATIRGRPAPKVTW--KRIGVDNVIRRGHVDQIDT 18329

Query: 1251  RT-LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
              T L+I + + +D  +Y+  L +   +    ++V+V++ P  +   +     K    +  
Sbjct: 18330 MTFLVIPESSREDSGKYSLTLSNPSGEKAVFVRVKVLDTPGPVGGLDATDITKTSCQLAW 18389

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             L        P   +IV  + + +   T  + D K  S  I  +       +++   N  G
Sbjct: 18390 LPPENDGGSPILNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAVNKYG 18449

Query: 1368  HA---DVEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
                  D   +    D   +P PP K ++LEI  +S  + W +P   G S I  Y+VEYQ+
Sbjct: 18450 IGLPQDSPKSYLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQ 18509

Query: 1422  IDTTE--WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
                 E  W S   +      +  LK N+ YRFR  A N +  S A E    ++V KE  +
Sbjct: 18510 DGQPEDKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEV-KEQLM 18568

Query: 1480  QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
                 +   +  +T      + +  +  G P P   W R    + T+
Sbjct: 18569 APKIIVSDV--VTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTS 18612



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 6/198 (3%)

Query: 1276  TTKLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKK 1330
             TT+  V   E+ P  +  + E +    +K G  + +        P P   W    +  K 
Sbjct: 19999 TTEPLVCKDEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKS 20058

Query: 1331  CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
                 + S    S++L+IK     + G Y +   N  G  D ++ V +LD P PPG     
Sbjct: 20059 SDIVQISSTPTSSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKVLDVPGPPGPIEAS 20118

Query: 1391  EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSY 1449
              + +    + W  PE  G  +I  Y++E +E     W  + +N+   +     L   + Y
Sbjct: 20119 SVSAEKCTLTWLPPEEDGGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEY 20178

Query: 1450  RFRAYAVNEVDISDASET 1467
              FR  AVN+    D +++
Sbjct: 20179 IFRVSAVNQYGTGDVTQS 20196



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 485  QKKLNEKIDKLPVF----EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540
            +KK  E+  KL +     EK        AP  +E+++ +       V+F C+V G P P+
Sbjct: 1822 EKKKEEEERKLTIPTIRPEKVALSPSMEAPKILERIQSQTVALADEVRFRCRVIGKPDPE 1881

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              WF+   +++ S     Y+ +D+V  LVIR+V  ED+ +    A N AG ASS   L+V
Sbjct: 1882 CQWFKNGILLEKSDRVYWYWPEDHVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLV 1941

Query: 601  EA 602
            +A
Sbjct: 1942 QA 1943



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 32/91 (35%), Positives = 50/91 (54%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F  +++P    +GS V+F+ +V G P P + WF+  + IK SQ   +  + D    L+
Sbjct: 3516 PCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLI 3575

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +  +   D+G +TC A N  G AS + ELIV
Sbjct: 3576 MSNIQQRDSGLYTCKAVNPFGEASCSAELIV 3606



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 70/295 (23%), Positives = 115/295 (38%), Gaps = 24/295 (8%)

Query: 1192  EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250
             E P I    +L   +   A T   L  +I  +    V W K   V++  ++ T+ +    
Sbjct: 13401 EPPEIQLDAKLLAGLTAKAGTKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGH 13460

Query: 1251  RTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
              TL I K   DD   Y    +++  ++T  + V +++ P     ++        S++T  
Sbjct: 13461 STLSIAKTKRDDTATYIIEAVNSSGRATATVDVNILDKPGPPAAFDI-------SEITNE 13513

Query: 1309  VDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
                 A+  P D+       +IV  K +      K S   K  +    K+      I+++ 
Sbjct: 13514 SCVLAWNPPRDDGGSKVTNYIVERKAVDSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVY 13573

Query: 1362  LENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
              EN  G      +  I+     D P PP K    +I   ++ + W EP+  G S I  Y 
Sbjct: 13574 AENQFGIGAPAEHAPIIARYPFDTPGPPYKLEPSDIAKDAVTLSWYEPDEDGGSPITGYW 13633

Query: 1417  VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             VE  E D  +WI      I  T   ++ L T   Y+FR  A N       S+ T+
Sbjct: 13634 VERYEPDHDKWIRCNKLPIRDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETD 13688



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 53/187 (28%), Positives = 85/187 (45%), Gaps = 13/187 (6%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKK---NKYDFEKRGHIR 1072
            P F + LQ     E   A  E +++     +V W RDG+++        +  F   G   
Sbjct: 6    PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSD-GRAV 64

Query: 1073 KLYIRNTSVHDEGEYSCILRD----ESCTAE--VTVVELPPEIITRLQNQKVNKGNKATF 1126
             +    T+ H  G +S    +     + TAE  VT    PP  I RLQ+  V +G++   
Sbjct: 65   LMIPAVTAAHS-GRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRL 123

Query: 1127 EIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
            ++ +T   A +V+++++G+EIQ S   Q+  DG    L I +   +D+G YS    NS  
Sbjct: 124  DVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSG 183

Query: 1186 TAILTVE 1192
             A  T E
Sbjct: 184  RATSTAE 190



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 3/120 (2%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT 1436
             +D P  PGKP + ++  +S  + W +PE+ G + I  Y+VE  +  T EW+ V  NI   
Sbjct: 13696 IDPPWAPGKPTVKDVAKTSAFLQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSL 13755

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             +  ++ L     Y FR  AVN    S+ SE ++   V+ + ++  P+  + L  +++  N
Sbjct: 13756 EHFLKGLMEKQEYSFRVRAVNVAGESEPSEPSD--PVLCKERLNPPSPPRWLLVVSSSRN 13813



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 61/289 (21%), Positives = 110/289 (38%), Gaps = 11/289 (3%)

Query: 1192  EEPSINFTLRLPEFILVPANTDAYLTVE--IPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
             E P+I     + + + V A     +T    +        W K     + ++   + S   
Sbjct: 20010 EPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPT 20069

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               TL I+  +  +  EYT    +       K+KV+V++ P      E          +T 
Sbjct: 20070 SSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKVLDVPGPPGPIEASSVSAEKCTLTW 20129

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             L   +        +I+  +   +   TK + +         K+   +  I+++   N  G
Sbjct: 20130 LPPEEDGGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYG 20189

Query: 1368  HADVEMN--VTILDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
               DV  +  V ++D    P PP KP I  +  +++ I W  P   G S I  Y+VE +E 
Sbjct: 20190 TGDVTQSGPVKMVDSFGPPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGYIVERKER 20249

Query: 1423  DTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                 W+  S K ++  +  +  L     Y FR  A N+    + SE ++
Sbjct: 20250 RGMRWVRASKKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQ 20298



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 82/336 (24%), Positives = 139/336 (41%), Gaps = 51/336 (15%)

Query: 509   APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
             AP   E ++   T  G +    CQ+ G P P+I W+R    +  S+ ++M  D  N +  
Sbjct: 30165 APCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLS 30224

Query: 569   VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             V+ +   ED G +TC A N AG   ++ +L+++A    H                     
Sbjct: 30225 VMTDE-QEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFH--------------------- 30262

Query: 629   LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESD 687
                  P F  K K  Y   G+ + L    +  P P I W +  + + P EN+ +   ES 
Sbjct: 30263 -----PGFPLKEK-YYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESY 30316

Query: 688   MHMYCSVLKITNV-KKFQEGTYTVVAVNREGEASLPIVLKIKTGEK----EPPQVIEPL- 741
              H     L I NV +K   G Y V   N+ G  ++  VL+++  +K    E P V++ L 
Sbjct: 30317 TH-----LVIRNVQRKTNAGRYKVQLSNKFG--TVDTVLRVEIQDKPLLPEGPVVVDALL 30369

Query: 742   -KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE 800
               S+I+           ++ N        K  +    + +   G T  +    P  ++  
Sbjct: 30370 KSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRV----PNLIESS 30425

Query: 801   GVY-TLKAENSEGIAET---SAVITVEEPTEENAEP 832
             G Y  + A+N  GI+E+    +V+ ++ P E+   P
Sbjct: 30426 GYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPGVP 30461



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+E L P     G  V  +CQ+ G P  +I+WF+    ++ S   +M +    +A L 
Sbjct: 7123 PFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEF-FKGIACLK 7181

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            + +V   D G +TC A+N+ G A+S+  L V+
Sbjct: 7182 LAKVAKSDIGEYTCKAENSIGSATSSCHLTVQ 7213



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 47/174 (27%), Positives = 75/174 (43%), Gaps = 9/174 (5%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS--QDFQMYYDDDN 564
           + AP F + L+     +GS   FE QV G P P+++WFR   ++  +     Q+ + D  
Sbjct: 3   TQAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGR 62

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            A L+I  V    +G F+  A N AG A+ST EL+V A  +       +           
Sbjct: 63  -AVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQV 121

Query: 625 XADI-LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
             D+ + GIP      P  ++  EG++I        + + D+  L   E    D
Sbjct: 122 RLDVRVTGIP-----APVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPED 170



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            +Q + P F  KL+   +  GS  Q EC V G     +TWF++   I+  +  +  +  +N
Sbjct: 5734 DQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIF-FEN 5792

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
             A+L I  +   D+G +TC+AKN AG    +  L V+ P S
Sbjct: 5793 AASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPS 5833



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 1/102 (0%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T ++    P F +K+      +G  VQFEC+V G    +++W +    ++   ++ M + 
Sbjct: 7211 TVQDVKTPPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSF- 7269

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            DDN A L I +     +G +TCVA N+ G AS   +L ++ P
Sbjct: 7270 DDNSAVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQEP 7311



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 1/129 (0%)

Query: 474   LMDENNYTQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
             L D+  YT     K  E   K  +   P +  E +M P+F   L      +G +V+F+ +
Sbjct: 31387 LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLR 31446

Query: 533   VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
             V G P P + W +    ++     ++  +D +   L IRE   ED+GT+   A N AG A
Sbjct: 31447 VSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGSA 31506

Query: 593   SSTTELIVE 601
             S    L VE
Sbjct: 31507 SCQATLKVE 31515



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 48/198 (24%), Positives = 80/198 (40%), Gaps = 10/198 (5%)

Query: 631   GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
             G  P   +  K      G   +L C+++  P P+I W   G+E++      ++ +   H 
Sbjct: 30163 GEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHS 30222

Query: 691   YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-G 749
                 L +   ++  EG YT  AVN  GE      L ++   +  P    PLK       G
Sbjct: 30223 ----LSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGF--PLKEKYYAGCG 30276

Query: 750   ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK---DEGVYTLK 806
              S+ L    +G P P I W    KP+         +T S T L  + V+   + G Y ++
Sbjct: 30277 TSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQ 30336

Query: 807   AENSEGIAETSAVITVEE 824
               N  G  +T   + +++
Sbjct: 30337 LSNKFGTVDTVLRVEIQD 30354



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 51/215 (23%), Positives = 83/215 (38%), Gaps = 9/215 (4%)

Query: 718   EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             E S P++ K  T  + P    + L+ M V+   +     +VVG+P+P + W KN K + A
Sbjct: 30545 EISEPVIPKSDTALRAP-FFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILA 30603

Query: 778   ----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
                 +  +     +   ++      D   Y ++A N  G   TS  + VE P +     P
Sbjct: 30604 DGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAK--IYLP 30661

Query: 834   LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
             L +     +       + +   ++  P P +TW +  EII+ +             LV  
Sbjct: 30662 LHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVFL 30721

Query: 894   NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
                   DSG Y   A N  G       V +DV  V
Sbjct: 30722 KGVQRKDSGYYIICAKNRFGMDKQ--TVELDVADV 30754



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 45/148 (30%), Positives = 71/148 (47%), Gaps = 10/148 (6%)

Query: 708   YTVVAVNREGEASLPIVLK---IKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPR 763
             + V+A N  G  S P       +   E   PQ+  E  KS+ ++ GE++ LS  + G P 
Sbjct: 27561 FRVIARNAVGTVSPPSQSSGYIMTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPV 27620

Query: 764   PTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             P +TW K+ K V K L   +     S   ++       G+YT++A+NS G  +   ++ V
Sbjct: 27621 PQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRV 27680

Query: 823   EEPTEENAEPPLFINRFQEITVKEKGTI 850
             ++ T    E PL   RF  I+  EK T+
Sbjct: 27681 QD-TPGPPEGPL---RFTNISA-EKATL 27703



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 7/135 (5%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753
             +TN+ +  E  + V+AVN +G++  P +L      K+    P V   L +  V+ G  + 
Sbjct: 22825 VTNLAQGGEYIFRVIAVNDKGKSD-PRLLASPVVAKDLAIEPTVRTKLSTYSVQVGYDLK 22883

Query: 754   LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYTLKAENSE 811
             + A++ G+P+PTITW K+   +K     +  DT  H+   +K    +D G+Y +   N  
Sbjct: 22884 IEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVL 22943

Query: 812   GIAE-TSAVITVEEP 825
             G  E T  +I +E+P
Sbjct: 22944 GQQEATVEIIILEKP 22958



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            ++ + P+F  KL+   +  G +++ +C+  G     I+WF     I    ++++ + + N
Sbjct: 6839 DKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTE-N 6897

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
              TL +  +   D+GT+ C A N+AG A ++  L+V+ P S
Sbjct: 6898 TCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPS 6938



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 3/152 (1%)

Query: 715   REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
             +E E S  + +K K       +++    S+IV +G+S      + G P PT+TW    + 
Sbjct: 32118 KESETSAEVSVK-KIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRT 32176

Query: 775   VKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
             V +        T   + L+   V+  DEG YT+  ENSEG  E    + + +P  +    
Sbjct: 32177 VVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEEVT 32236

Query: 833   PLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             P  +   +         IK       +PVPS+
Sbjct: 32237 PTQVKSPEPSVASPVPPIKSPESSVTSPVPSV 32268



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 102/484 (21%), Positives = 193/484 (39%), Gaps = 44/484 (9%)

Query: 154   EKSDLFDSQEDESKPDV--SQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV 211
             EK+   D    + KP +   + P  +  +A + P   E   +P  K  +   ++P K   
Sbjct: 10435 EKTKEIDVPVKKEKPSIPDKKEPDEVSVKAVTRPAKDEVPTEPKEKLVKGKGKIPSKDQE 10494

Query: 212   PDD---KETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXX 268
             P+    K  ++ P++ + + K      +RK +E+S P      D  +             
Sbjct: 10495 PEKVQLKPFTKKPSAGSPKEKEAAEPKDRKPIELS-PLSRAPKDDIKKEPSIPTKKIDSQ 10553

Query: 269   XXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGS-------IKQNGILSRNIKEAA 321
                    ++ K      ++  T+ PP+ + P+             + + G+L +  +E  
Sbjct: 10554 ETPDKAKEVEKISTPVPVEDKTT-PPKKVTPVKKITPKEDEKKPIVIKKGVLPKEAEEKE 10612

Query: 322   KVK-------KQVFVPPKLPD--VEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372
             ++K       K    P K+P   VEKT+  + +      ++      + I  K + E + 
Sbjct: 10613 EIKLKPVERTKSGIEPEKIPSPKVEKTKPAESVPVQRKPIDDLTKTPKTISPKDSTEAVI 10672

Query: 373   KEDVPEQYTITPRKSSAQKIDEIV--DEVTIKKRLNPFEIFYTPVEVRCGDTVFAV-YSY 429
              + VP +  I+P++  +++  +I   D++ + K L+P  +    V  +  + VF   + Y
Sbjct: 10673 LKKVPHK--ISPKQEKSEETPQISGDDKIPVLKELSPGAVELRKVSTQFEEEVFEEEFEY 10730

Query: 430   VAETDEAINLVEGERLYILDT---SNQDWWYVQKHLTEEKGWVP---AQYLMDENNYTQY 483
              AE ++      G  L   D+      +  Y+++   E  G      A+         + 
Sbjct: 10731 EAEYEDEEEEAWGWELASRDSYGSEGSEEQYLEEGALETPGMPGGRRAKQTPSPGEGGKG 10790

Query: 484   LQKKLNEKIDKLPVFEKPTSEEQSMAPI-FVEKLRPKHTPD----GSTVQFECQVEGYPR 538
                K     DK P  + P   +    P+ FV++L+     +    GS+  FECQ+   P 
Sbjct: 10791 RGLKPGAGGDK-PPGDSPFGFQLKAVPLKFVKELKDIVLQEAESIGSSAVFECQIS--PS 10847

Query: 539   PQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
               IT W +  + ++ S   + +  D     L I +V   D G +TCVAK      +ST +
Sbjct: 10848 TAITTWMKDGSNLRESPKHK-FTSDGKDRKLQIIDVQLSDTGEYTCVAKLGNKEKTSTAK 10906

Query: 598   LIVE 601
             LIVE
Sbjct: 10907 LIVE 10910



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 7/134 (5%)

Query: 708   YTVVAVNREGEASLPIVLKIKTGEKE--PPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764
             + V AVN+ G+       K  T +KE  PP + +E    ++VR GE+ I+ ++  G P P
Sbjct: 16458 FRVSAVNQIGQGKPSFSTKPVTCKKEFEPPNLDLEFRDKLVVRVGETCIIQSRYTGKPEP 16517

Query: 765   TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             TI W KN++ ++A   +   +  +  S+TI K K+    G Y +  ENS G  +    + 
Sbjct: 16518 TIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKR-DHSGKYMVVLENSIGTRKGICTVN 16576

Query: 822   VEEPTEENAEPPLF 835
             V +  +    P +F
Sbjct: 16577 VVDRPQPPEGPVIF 16590



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 49/204 (24%), Positives = 87/204 (42%), Gaps = 10/204 (4%)

Query: 634   PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
             P F  + +   V   ++     ++V  P+P + W   G+EI+ D    + ++     Y  
Sbjct: 30561 PFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILAD-GAKIKVQEFKGGYFQ 30619

Query: 694   VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752
              L I+N  +     Y + A N+ G  S  + L ++   K   P  ++ + ++   +GE V
Sbjct: 30620 -LVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVV 30678

Query: 753   ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAEN 809
              +   + G P P +TW K  + +          T S T    LK  + KD G Y + A+N
Sbjct: 30679 TIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKN 30738

Query: 810   SEGIAETSAVITVEEPTEENAEPP 833
               G+ +     TVE    +  +PP
Sbjct: 30739 RFGMDKQ----TVELDVADVPDPP 30758



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 24/79 (30%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G T ++ C+V GYP P++ W+    +I+ S+ F+++Y  D +  L I +    D+G   
Sbjct: 1626 EGETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRLHY--DGIHYLEITDCKSYDSGDVR 1683

Query: 583  CVAKNAAGFASSTTELIVE 601
             +A+N  G A  T +L ++
Sbjct: 1684 VLAENPEGTAEHTVKLEIQ 1702



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 64/262 (24%), Positives = 101/262 (38%), Gaps = 32/262 (12%)

Query: 1428  ISVKNITKTQTSIQNLKTNSSYRF-RAYAVNEVDISDASETTEYY---------KVIKET 1477
             I VK+I +    +   K  S  R   AYA  E+ +       EYY         + I ++
Sbjct: 31258 IYVKDIEECDDGLYRCKVVSEDREDNAYA--ELFVETVRSFREYYLGRSLKKPRRRIDKS 31315

Query: 1478  KI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----E 1530
             KI  + P    PL N +    ED+         P+P VTW + G ++K     Y     +
Sbjct: 31316 KILQRPPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPKKYTFTSDK 31375

Query: 1531  NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----- 1585
                              Y  +A N  GE   SC   +   P   ++ + ++   K     
Sbjct: 31376 GLYQLMIHNVDLSDDAEYTVVANNKFGE--DSCKARLNVAPH-AVAEDTMRPMFKRLLAN 31432

Query: 1586  ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHS 1640
                  G        + G P P + W KNG  LE   +  +  ++    ++ I+E     S
Sbjct: 31433 IDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDS 31492

Query: 1641  SKYTIEASNTAGTSSVEVTLKV 1662
               Y + A+NTAG++S + TLKV
Sbjct: 31493 GTYRVTATNTAGSASCQATLKV 31514



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 14/138 (10%)

Query: 639   KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
             KP +  V EG      C +   P P + W+ +G  +V    I V+       Y S L+I+
Sbjct: 32142 KPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTT----QYKSTLEIS 32197

Query: 699   NVKKFQEGTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQG 749
             +V+   EG YTVV  N EG+     +L I   I   E  P QV  P  S+      ++  
Sbjct: 32198 SVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEEVTPTQVKSPEPSVASPVPPIKSP 32257

Query: 750   ESVILS-AQVVGNPRPTI 766
             ES + S    V +P P++
Sbjct: 32258 ESSVTSPVPSVKSPEPSV 32275



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 8/146 (5%)

Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL---EGIPPTFSKKPKAQYVDE 647
           F+     L++ A  + H    +V            A++L   E  PP F ++ ++  V +
Sbjct: 58  FSDGRAVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQ 117

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           GS + L+ R+  IP P + +  +G EI    +  +  + D++     L I        GT
Sbjct: 118 GSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYS----LLIAEAFPEDSGT 173

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKE 733
           Y+V A N  G A+    L ++ GE+E
Sbjct: 174 YSVSASNSSGRATSTAELLVQ-GEEE 198



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 56/243 (23%), Positives = 89/243 (36%), Gaps = 21/243 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561
            +E+   P F +KL          V FEC++   G P   + W      ++ +   +M  +
Sbjct: 1469 KEKQQKPHFKKKLTSVRMKRFGPVHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI-N 1527

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------------DHG 608
            +    +L     +  D+G  TC A N  G   ++  LIV+   S                
Sbjct: 1528 EFGYCSLDYEVAYSRDSGVITCRATNKFGADQTSATLIVKDEKSLVEDSQLPEGRKVQRM 1587

Query: 609  SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
             EM               D+ E   P     P+   V EG      CR+   P P + W 
Sbjct: 1588 DEMERIAHEGGPSGVTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWY 1647

Query: 669  FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
              G  I   +   +  +  +H     L+IT+ K +  G   V+A N EG A   + L+I+
Sbjct: 1648 LNGLLIRKSKRFRLHYDG-IH----YLEITDCKSYDSGDVRVLAENPEGTAEHTVKLEIQ 1702

Query: 729  TGE 731
              E
Sbjct: 1703 QKE 1705



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 59/243 (24%), Positives = 90/243 (37%), Gaps = 33/243 (13%)

Query: 486   KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
             KK   +IDK  + ++P        P F   L  +    G  V+F   +  +P P +TW +
Sbjct: 31306 KKPRRRIDKSKILQRP--------PEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLK 31357

Query: 546   QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
                 IKP      +  D  +  L+I  V   D   +T VA N  G  S    L V AP  
Sbjct: 31358 AGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNV-AP-- 31414

Query: 606   DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665
                                 A   + + P F +        EG  +  + R+   P P +
Sbjct: 31415 -------------------HAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTL 31455

Query: 666   AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
              W   G+ +     + V ++ D+  +  +L I        GTY V A N  G AS    L
Sbjct: 31456 KWEKNGKPLEFRPQVEV-VQEDVDYF--ILHIRETLIEDSGTYRVTATNTAGSASCQATL 31512

Query: 726   KIK 728
             K++
Sbjct: 31513 KVE 31515



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 46/185 (24%), Positives = 82/185 (44%), Gaps = 16/185 (8%)

Query: 1008  TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK------N 1061
             T + +   + E IR+ +     E +V I  +E  S T +    R    + P++      +
Sbjct: 31821 TYIELMRPVSELIRQPRARIPTEAEVEI--IERRSPTPERTRPRSPSPVSPERRSSRSSS 31878

Query: 1062  KYDFEKRGHIRKLY-IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
             +++   R  I   Y  R  ++  E +Y  +      T +   ++  P I  R+++ +V  
Sbjct: 31879 RFERSARFDIMSRYEARKAALKSERKYQVV------TQQPFSLDHAPRITVRMRSHRVPC 31932

Query: 1121  GNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
             G    F + + +K DA ++WF +G +IQ S+  Q T       L+I DC  +D G Y   
Sbjct: 31933 GQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVLSLQINDCQAEDTGTYRAL 31992

Query: 1180  VGNSK 1184
               NSK
Sbjct: 31993 CTNSK 31997



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 26/231 (11%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             +  +   QE    V+A N +G++     + P++ K  T E   P       +  V+ GE 
Sbjct: 23907 VAGLSSGQEYLLRVLAYNEKGKSDPRPLASPVIAKDVTIE---PSFKLTFNTYSVQSGED 23963

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809
             + +     G P P I W K+ + +K     +   T + T+LK K+   +D G YT+ A N
Sbjct: 23964 LKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATN 24023

Query: 810   SEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
             + G + E  A+I +++P      PP    +  E++     T  +++     PV +     
Sbjct: 24024 NIGTVTEEVAIIILDKP-----GPPTGPVKIDEVS----ATYVVIS--WEPPVYTGGCQI 24072

Query: 869   NNEIISPSETITQNFDGENIELVITNVD-SEIDSG---DYKCVASNSAGKS 915
             NN ++   +T T N+   +  +  T +  S++ +G    ++  A N  GKS
Sbjct: 24073 NNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKS 24123



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 45/207 (21%), Positives = 87/207 (42%), Gaps = 13/207 (6%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533
            Q+PT  +PL+++               G P P+V+W+RDG+ L  A       +  + R 
Sbjct: 4    QAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRA 63

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC--VVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                          +   A N  G+  ++   +V  +  P   I         + G +  
Sbjct: 64   VLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQ-GSQVR 122

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +   + GIP P V +Y+ G ++++  ++ I        + I E     S  Y++ ASN++
Sbjct: 123  LDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSS 182

Query: 1652 G--TSSVEVTLKVYDK--PSKPEGPVI 1674
            G  TS+ E+ ++  ++  P+K    +I
Sbjct: 183  GRATSTAELLVQGEEEAVPAKKSKTII 209



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 3/140 (2%)

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            EG    + +  E IA       V          P  +   + I V E  T K   RVT  
Sbjct: 1580 EGRKVQRMDEMERIAHEGGPSGVTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGY 1639

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P + WY N  +I  S+    ++DG +  L IT+  S  DSGD + +A N  G + H  
Sbjct: 1640 PTPKVNWYLNGLLIRKSKRFRLHYDGIHY-LEITDCKS-YDSGDVRVLAENPEGTAEHTV 1697

Query: 920  RVTIDVEKVTFVKHLQKSYE 939
            ++ I  +K  F   L+++ E
Sbjct: 1698 KLEIQ-QKEDFRTILRRAPE 1716



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV+         G+ ++ ECQV+      I W R    +  + D ++ +++  +A L 
Sbjct: 4803 PSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFEE-KIACLD 4861

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I++   +D GT+TC A N AG +S ++ + V+ P
Sbjct: 4862 IQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQEP 4895



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 7/137 (5%)

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
            +YA  E D +   ET      +KE  +  PT+   LKN+T    E + L C   G P P 
Sbjct: 715  SYAGEEWD-TKVPETAAIPSAVKEPVVP-PTLIAGLKNVTVTEGESVTLECQISGHPTPA 772

Query: 1513 VTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            + W+R+  +++ +   + TYE +                + C A ++ G + TSC + ++
Sbjct: 773  IMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFTCTATSEAGTISTSCYLLVK 832

Query: 1569 QKPVITISNEDIKQKHK 1585
                I  S E+I  + K
Sbjct: 833  VSEEIE-SREEITIQEK 848



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 1/102 (0%)

Query: 500  KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            K T +E    P+F +KL P     G TV+ EC + G    ++TW +    I+   ++++ 
Sbjct: 7305 KLTLQEPRYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKIS 7364

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
               +N   L I +    D+G ++C A N  G  S +TE+ V+
Sbjct: 7365 C-VENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVK 7405



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 6/133 (4%)

Query: 698   TNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             T + +  E  + + AVN  G +    S P+V+K +T   E        K+++ + G+++ 
Sbjct: 20661 TELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVAKAGDNLK 20720

Query: 754   LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSE 811
             +   V+G PRP + W K ++ +K     +  +T S TIL   ++  KD G Y++  +N  
Sbjct: 20721 VEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQYSMTGKNIL 20780

Query: 812   GIAETSAVITVEE 824
             G    +  + V +
Sbjct: 20781 GTVTENITVQVHD 20793



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 4/115 (3%)

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           + ET+A+ +     +E   PP  I   + +TV E  ++ L  +++ +P P+I W+R +  
Sbjct: 725 VPETAAIPSA---VKEPVVPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYR 781

Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
           I  S      ++     L+I    +E DSG + C A++ AG  S    + + V +
Sbjct: 782 IENSIDFQITYEKSYARLMIREAFAE-DSGRFTCTATSEAGTISTSCYLLVKVSE 835



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 17/163 (10%)

Query: 1047  VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV 1102
             V W + G  IKP   KY F     + +L I N  + D+ EY+ +      ++SC A + V
Sbjct: 31353 VTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNV 31412

Query: 1103  V-------ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQL 1154
                      + P     L N    +G    F++ ++   A  ++W K+G  ++F   +++
Sbjct: 31413 APHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEV 31472

Query: 1155  T-IDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192
                D     L I +  ++D+G Y    +   G++ C A L VE
Sbjct: 31473 VQEDVDYFILHIRETLIEDSGTYRVTATNTAGSASCQATLKVE 31515



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%)

Query: 697   ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGES 751
             +T++ +  E  + V+A N  G    A +P V+K+    + P   +E +  +  +VRQG  
Sbjct: 29727 LTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEKIYQEGYVVRQGGV 29786

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + LS  + G P PT  W K  + +      +  +  +  ++K     D G Y L  EN  
Sbjct: 29787 IRLSVPIKGKPLPTCKWTKEGRDISHRAMIATSEERTELVIKEAHRDDTGTYDLVLENKC 29846

Query: 812   G-IAETSAVITVEEPTEENAEPPLFINRFQEITVK--------EKGTIKLVARVTRNPVP 862
             G  A    V  +  P  +  E PL  +  Q  +V+        + G+      V R  VP
Sbjct: 29847 GRKAVYIKVKVIGRP--DPPEGPLEFDDIQARSVRVSWRPPSDDGGSDIFGYIVERREVP 29904

Query: 863   SITWYRNNEIISPSETITQNFDGENIE 889
                WY  +  +  +  + +    EN+E
Sbjct: 29905 KAAWYTVDSRVVDTSLVVKGLK-ENVE 29930



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 9/129 (6%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860
             +  KA N+ G +E S  +TV    +E A     +  F+   I V++   I++ A VT  P
Sbjct: 15137 FRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVTGLP 15196

Query: 861   VPSITWYRNNEII-SPSETI---TQNFD--GENIELVITNVDSEIDSGDYKCVASNSAGK 914
             +P I W +++ +I  P+E +   T+  D    + +L I  V + +D G Y   ASN  G 
Sbjct: 15197 MPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGV-TRLDKGTYTVTASNRLGT 15255

Query: 915   SSHGARVTI 923
              SH   V +
Sbjct: 15256 LSHSVTVEV 15264



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 10/107 (9%)

Query: 711   VAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
             V+V  E    +PI+      E  PP+V   +E    ++V+ G +V L A+V G P P + 
Sbjct: 18943 VSVPSEESDVIPII-----AEHVPPRVEISLEMKNLIVVKAGANVCLEAEVYGKPMPKVV 18997

Query: 768   WCKNNKPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEG 812
             W K+  P+K A   K     H +++ L     K+ G YT+ AEN  G
Sbjct: 18998 WKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSG 19044



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%)

Query: 503   SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
             +++ ++ P    KL       G  ++ E ++ G+P+P ITW +  + +K +    +  D 
Sbjct: 22858 AKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNV-ADT 22916

Query: 563   DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              +  TL I++   ED G +  V  N  G   +T E+I+
Sbjct: 22917 AHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIII 22954



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 41/214 (19%), Positives = 84/214 (39%), Gaps = 26/214 (12%)

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----E 1530
            E K + P  E  L        E +  T    G P+PKV W+ +GK + T+ + Y      
Sbjct: 3398 ERKREKPVFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAI-TSSSIYTFVEER 3456

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV---- 1586
            +                Y C A N  G+     ++ ++    ++ + + +++  K+    
Sbjct: 3457 DEYSLIITKVKKDYEGEYSCTASNRFGQTTCKTILKVELSQ-LSAAEKWVEKMFKIPGQP 3515

Query: 1587 --------------GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIR 1631
                          G E      + G P P+V W+K  +++++ +  ++    + +  + 
Sbjct: 3516 PCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLI 3575

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            +  +++  S  YT +A N  G +S    L V+ K
Sbjct: 3576 MSNIQQRDSGLYTCKAVNPFGEASCSAELIVFHK 3609



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 9/117 (7%)

Query: 712   AVNREGEASLPIVLKIKTGEKEPPQV-IEP-LKSMI-VRQGESVILSAQ-VVGNPRPTIT 767
             A++   E + P+V K    E EPP + I+P +K  + V+ G +++++A  ++G P PT  
Sbjct: 19992 AISAPSETTEPLVCK---DEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAV 20048

Query: 768   WCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             W K  +  K+  +   S   T S   +K    K+ G YT+ A N  GI +    + V
Sbjct: 20049 WSKAGREFKSSDIVQISSTPTSSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKV 20105



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 5/121 (4%)

Query: 697   ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGES 751
             ++N++   +  + V A+N EG    + +  V+++   E+ P   +  E  K+++V+ G S
Sbjct: 20370 VSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGAS 20429

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + +   + G P P + W K N P+K        +++++ ++      D G Y L  EN  
Sbjct: 20430 IRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVA 20489

Query: 812   G 812
             G
Sbjct: 20490 G 20490



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 6/138 (4%)

Query: 1558  EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
             E ETS  V ++ K   T+S + + + H +    GD       I+G P P V W   G  +
Sbjct: 32119 ESETSAEVSVK-KIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTV 32177

Query: 1614  ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
              +    +++T +  S + I  ++ S    YT+   N+ G      TL + +KP   E   
Sbjct: 32178 VSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAI-NKPILKEEVT 32236

Query: 1674  IMREISRESVTIEWKPPL 1691
               +  S E       PP+
Sbjct: 32237 PTQVKSPEPSVASPVPPI 32254



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 5/119 (4%)

Query: 708   YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP--LKSMIVRQGESVILSAQVVGNPRPT 765
             + V + N  GE++      I   E+    V++   + +++V+ GESV L A + G P+PT
Sbjct: 17841 FRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGESVRLEAGLRGKPQPT 17900

Query: 766   ITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             +TW K +K     P  S   G  +S  +L   K  D G Y + A N  G     A +TV
Sbjct: 17901 VTWVK-DKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVTV 17958



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 7/155 (4%)

Query: 672   EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG-----EASLPIVLK 726
             E+ + DE   V I S   +  +   ++++K      Y V AVN  G     E   P+  K
Sbjct: 26839 EQRIADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAK 26898

Query: 727   IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786
                 E +    I      I + G  V +   + G P P +TW K +K +      +  +T
Sbjct: 26899 DILEEADVDLDISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNT 26958

Query: 787   -HSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819
              +S T++ PK  +D+ G Y L+ EN  G  +T  V
Sbjct: 26959 EYSTTLIIPKVTRDDTGKYLLEIENGVGEPKTITV 26993



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 15/143 (10%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+   +   I G P P ++W++   ++EN  ++ IT ++  + + I+E     S ++T  
Sbjct: 756  GESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFTCT 815

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPL----DDGGLELTKY 1701
            A++ AGT S    L V           +  EI SRE +TI+ K  +    D+   E++  
Sbjct: 816  ATSEAGTISTSCYLLV----------KVSEEIESREEITIQEKQTVVEAKDETMSEISSV 865

Query: 1702 AIEKHEPDNNRWIKVADVDRDVE 1724
            +++   P    ++K   V + VE
Sbjct: 866  SVDTGAPAAPFFVKKPVVQKLVE 888



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-T 1436
             L+ PSPP    ++    +S  + W  PE  G S I  Y+VE +++    W +V    K  
Sbjct: 13796 LNPPSPPRWLLVVSSSRNSAELKWTAPERDGGSPITNYIVEKRDVRRKGWQAVDTTVKEL 13855

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             + ++  L   S Y FR  A N V  S+  E
Sbjct: 13856 KYTVTPLNEGSLYVFRVAAENAVGPSEFCE 13885



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 5/109 (4%)

Query: 710   VVAVN--REGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
             VVA+N   EGE  L   + ++   + P     I     ++VR GE + + A V G P P+
Sbjct: 14846 VVAINCAGEGEPGLTDAVIVRNPAEVPVIELDISVRNGVVVRAGEMLRIPAHVTGRPPPS 14905

Query: 766   ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             + W K++  + K      +    S  ++K  K  D G Y ++A N  GI
Sbjct: 14906 LKWTKDDGDLEKDRMEVEEAGQDSTVVIKTTKRSDHGKYQIQAANPSGI 14954



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNP 860
             + + A NSEG+ E S V  V E  +    P   ++    + + VK   +I++   +   P
Sbjct: 20381 FRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGASIRIFVPIKGRP 20440

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
              P + WY+ N  +     I      E+  LV+    +  D+G Y     N AGK +    
Sbjct: 20441 APEVVWYKENVPLKGRAHIDTT---ESYTLVVIPECTRYDAGKYVLTLENVAGKKTGFVN 20497

Query: 921   VTI 923
             V +
Sbjct: 20498 VRV 20500



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 11/147 (7%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEK-EPPQV---IEPLKSMIVRQGES 751
             IT + + QE    + A+N+ G    +PI   +K  +K + P++    E  K ++V  G S
Sbjct: 23617 ITKLTEHQEYKVRICALNKLGVGEPVPIQGSVKPVDKMDAPEIELDSELRKGIVVHAGGS 23676

Query: 752   VILSAQVVGNPRPTITWCKN--NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             + ++    G P P I W K+  + P KA   K    TH +TI    +  D G YTL  +N
Sbjct: 23677 MRINIPFKGRPIPEINWTKDDGDLPDKAQIDKGPDFTH-LTINICDR-NDAGKYTLTLQN 23734

Query: 810   SEGIAETSAVITVEEPTEENAEPPLFI 836
             S G    SA ++V+      A   LF+
Sbjct: 23735 SAG--TKSAFVSVKVLDTPGAPQNLFV 23759



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 63/270 (23%), Positives = 105/270 (38%), Gaps = 32/270 (11%)

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--IT 880
            +E   E    P+F+ +       E  T +   +V   P+P   W+ + + +    T  I 
Sbjct: 1219 DESQLERLYKPVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIV 1278

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE----KVTFVKHLQK 936
               DG    +V+  +    DSG++  VA N AGK++    +T++ +    +  F++ L K
Sbjct: 1279 VKEDGTQSMIVVPAMPQ--DSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQFIEKL-K 1335

Query: 937  SYETEEGKTV-------------ILECQTSHTVST-KWYHNKKE-ISGMDHREIIQEGRX 981
            +   +EG  V             I+  + S  +S  K+ H K E   G  H +I Q    
Sbjct: 1336 NISVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGS 1395

Query: 982  XXXXXXXXXXXDVG--VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
                         G    +C V  +   T     E +PE    +     K KDVA  E+E
Sbjct: 1396 DSAWYTATAINKAGRDTTRCRVNVEVEYT-----EPVPERRLIIPKGTYKAKDVAPPEIE 1450

Query: 1040 -INSETADVVWERDGEIIKPKKNKYDFEKR 1068
             ++       WE      K K+ K  F+K+
Sbjct: 1451 PLHLRYGQEQWEEGDLYDKEKQQKPHFKKK 1480



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRN 859
             + +K EN+ G++     + V    +E   PP+    +   + I VK   TI+L A +   
Sbjct: 17149 FRVKTENAIGLSRPDTTVPVL--CQEKLVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGL 17206

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHG 918
             PVP+  W  + E I  SE  T+  D +N   V++  D +   +G Y    SNSAG  +  
Sbjct: 17207 PVPTAKWVIDGEEIK-SEGNTK-IDTDNFSTVLSIADCTRNHTGIYILTVSNSAGSKTVS 17264

Query: 919   ARVTI 923
               VT+
Sbjct: 17265 LNVTV 17269



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 38/136 (27%), Positives = 66/136 (48%), Gaps = 12/136 (8%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLK---SMIVRQG 749
             ++ + + Q+  + V+A N  G +S+P      +  K  E +PPQ+    K   +++V  G
Sbjct: 22136 VSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKD-EVDPPQIDLDAKYSQNVVVNAG 22194

Query: 750   ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
             ES  + A ++G P P++ W K+ + +         +T   T L  K+    D G YTL  
Sbjct: 22195 ESFRIDAGILGKPIPSVHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLL 22254

Query: 808   ENSEGIAETSAVITVE 823
             +N  G  E S +I V+
Sbjct: 22255 KNVGG--EKSVIINVK 22268



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 89/439 (20%), Positives = 165/439 (37%), Gaps = 37/439 (8%)

Query: 780   TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFI 836
             T   G T +    K    K E  + + A N  G+ ET+ +   + +E+  E   +  L  
Sbjct: 22524 TPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEA-PDIDLDA 22582

Query: 837   NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
             +  + ITV+  G+++L   +   P P + W +    I+ +  I  +       LVI NV 
Sbjct: 22583 DLRKMITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQI--DITSSFTSLVIENV- 22639

Query: 897   SEIDSGDYKCVASNSAGKSSH--GARV--TIDVEKVTFVKHLQKSYETEEGKTVILE--C 950
             +  DSG Y     N++G  S     RV  T D+     VK + K+  T   +  +L+   
Sbjct: 22640 NRFDSGKYTLTLENASGTKSAFISVRVLDTPDMPANFRVKEITKNSVTLTWEPPLLDGGA 22699

Query: 951   QTSHTVSTKWYHNKKEISGMD-------HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             +    +  K    +K  S +          E ++EG              +G+       
Sbjct: 22700 KIKSYIVEKRESTRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGL------P 22753

Query: 1004  QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
              ET   L + E +P+   K+   +V  K V++   +   +    +   + E+    ++K+
Sbjct: 22754 AETPEPLKISE-VPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKDQDKW 22812

Query: 1064  DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP---------PEIITRLQ 1114
                 +       + N +   E  +  I  ++   ++  ++  P         P + T+L 
Sbjct: 22813 SLCAQVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKDLAIEPTVRTKLS 22872

Query: 1115  NQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
                V  G     E  ++      + W KDGS ++ +  + +        L I D   +D 
Sbjct: 22873 TYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDG 22932

Query: 1174  GEYSCEVGNSKCTAILTVE 1192
             G Y+  V N       TVE
Sbjct: 22933 GMYNIVVANVLGQQEATVE 22951



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 69/350 (19%), Positives = 130/350 (37%), Gaps = 36/350 (10%)

Query: 1284  VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             ++  P+I    R +R+  G +    ++ Q+ P  N +W  N + I++    + +  S   
Sbjct: 31915 LDHAPRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVL 31974

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------------DKPSPPG-KPNIL 1390
             SL I   +  D G Y+    N+ G A     + +             D+ +P    P+I 
Sbjct: 31975 SLQINDCQAEDTGTYRALCTNSKGEASDYATLDVSGGAFTTYSSRRRDEEAPTQIVPDIT 32034

Query: 1391  EID---SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ---TSIQNLK 1444
             + D   S++I        +         + E  E+ + E    + +  +     S + L 
Sbjct: 32035 KTDYYHSTTIRASSASRTHLEIQEFKTKLTERHEVSSFEKYESQRLASSPIRYASTEYLS 32094

Query: 1445  TNSSYRFRAYAVNEVDISDASETTEY-------YKVIKETKIQSPTVEKPLKNITTEPNE 1497
             + S      +  +E  +S  S+  E         K IK T + +  + KP   I +E  +
Sbjct: 32095 SASYSSSERHTTSEKHVSSESKLKESETSAEVSVKKIKAT-LSAKILTKPHSLIVSE-GD 32152

Query: 1498  DIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAF 1553
                  C   G P P VTW  +G+ + ++     +T + +               Y  +  
Sbjct: 32153 SARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVE 32212

Query: 1554  NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
             N  G+ E  C + I  KP++    E++        E  V + +  I  PE
Sbjct: 32213 NSEGKQEARCTLAI-NKPIL---KEEVTPTQVKSPEPSVASPVPPIKSPE 32258



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 1/91 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F ++++      GS+ +FEC++E  P     WF+    ++ S+  ++     + ++L 
Sbjct: 4615 PVFRQRIQNLEVNVGSSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRI-ISRHHTSSLE 4673

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            I      D+G +TC A N  G  S + +L V
Sbjct: 4674 IFSPAVADSGEYTCKASNRHGSDSCSAKLTV 4704



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 695   LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
             LK   + +F+        V   GE +  I +K +T   E        + ++V  G  + +
Sbjct: 16153 LKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRI 16212

Query: 755   SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAENSE 811
              A V G P P I W   N+    LP ++  +T SI+   ++K    + +G+YTL A+N+ 
Sbjct: 16213 LAYVSGKPAPEIIW---NRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYTLTAKNAG 16269

Query: 812   GIAETSAVITV 822
             G  + + ++ V
Sbjct: 16270 GERKKAVIVEV 16280



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 10/132 (7%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIV---LKIKTGEKEPPQVIEPLK----SMIVRQG 749
             +T++ + ++  + V+A N  G  S+P     L     E  PP+     K    ++ +R G
Sbjct: 28635 VTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKAELDSKLVGETISIRAG 28694

Query: 750   ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807
               ++L A V G P P + W K +K +      S     T ++ I+K     D G Y L  
Sbjct: 28695 SDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYSLTYTSTRAMAIIKSCDRNDTGRYILTV 28754

Query: 808   ENSEGIAETSAV 819
             +N+ GI +TSAV
Sbjct: 28755 KNASGI-KTSAV 28765



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 509   APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
             AP    ++R    P G   +F   V+  P   I WF     I+ S  +Q + +   V +L
Sbjct: 31918 APRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQ-FTNMSGVLSL 31976

Query: 569   VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              I +   ED GT+  +  N+ G AS    L V
Sbjct: 31977 QINDCQAEDTGTYRALCTNSKGEASDYATLDV 32008



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 5/98 (5%)

Query: 1571  PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL---ENDKEYNITTKEKT 1627
             P I    EDI  +   G    V     G P P + W + G KL   E+   ++I T E  
Sbjct: 32662 PRIEALPEDISVE--TGKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTEDL 32719

Query: 1628  SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
             + + I  +K + +  YT++ SN  G+    VT+ +  K
Sbjct: 32720 TTLIITGVKETDAGAYTLKLSNEHGSDLATVTISIRSK 32757



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 2/75 (2%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860
             + ++AEN+ G+++ S    + + T+    P +F++   +  + VK    I+L A ++  P
Sbjct: 14369 FRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKRGEEIRLDANISGFP 14428

Query: 861   VPSITWYRNNEIISP 875
              P ITW RNN  I P
Sbjct: 14429 YPQITWMRNNATIWP 14443



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 11/136 (8%)

Query: 696   KITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV---IEPLKSMIVRQG 749
             ++T + + Q   Y V A+N+ G AS P       +    KEPP++    + L  +  + G
Sbjct: 13362 EVTGLIEGQWYAYRVRALNKLG-ASKPCKSTDEILAVDPKEPPEIQLDAKLLAGLTAKAG 13420

Query: 750   ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
               + L A + G P P + W K +   KP   +   +     +++I K K+  D   Y ++
Sbjct: 13421 TKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKR-DDTATYIIE 13479

Query: 807   AENSEGIAETSAVITV 822
             A NS G A  +  + +
Sbjct: 13480 AVNSSGRATATVDVNI 13495



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 14/127 (11%)

Query: 697   ITNVKKFQEGTYTVVAVNREG------EASLPIVLKIKTGEKEPPQVI--EPLKSMIV-R 747
             +T + + Q   + ++A N  G      E++ P+ +K    + +PP++   + L+ ++V +
Sbjct: 25381 VTGLIEDQRYDFRIIAKNAAGLFSEPSESTGPVTVK---DDVDPPRITIEDKLRQLVVIK 25437

Query: 748   QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTL 805
              GE + + A++ G P P I+W K+ K ++A        T + T  I++    +D G Y L
Sbjct: 25438 AGEILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVL 25497

Query: 806   KAENSEG 812
               +N  G
Sbjct: 25498 TLQNVAG 25504



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 12/126 (9%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P+  W+ +G ++ ND  + I  KE  T  + +       S ++T+ A N AG +
Sbjct: 1252 VVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKT 1311

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-ELTKYAIEKHEPDNNRW 1713
            +V +TL V  K +    P  + ++   SV         +G L EL   AI    PD   W
Sbjct: 1312 TVSMTLTVEAKENLVR-PQFIEKLKNISV--------KEGSLVELAVKAIGNPLPD-IVW 1361

Query: 1714 IKVADV 1719
            +K +D+
Sbjct: 1362 LKNSDI 1367



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 14/147 (9%)

Query: 694   VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS-----MIVRQ 748
             ++ + N+ +     +   AVN  GE+   I + +   + E    +  LK      + VR+
Sbjct: 15123 IMTVDNLDELHMYEFRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRK 15182

Query: 749   GESVILSAQVVGNPRPTITWCKNN----KPVKAL--PTKSDGDTHSITILKPKKVK--DE 800
              E + + A+V G P P I W K++    KP + L   TK      S T L    V   D+
Sbjct: 15183 NEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDK 15242

Query: 801   GVYTLKAENSEGIAETSAVITV-EEPT 826
             G YT+ A N  G    S  + V + PT
Sbjct: 15243 GTYTVTASNRLGTLSHSVTVEVLDRPT 15269



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 6/136 (4%)

Query: 710   VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
             V +V+   E   P+      G  E     E L  +  + G +V L   +V  P+PTI W 
Sbjct: 26483 VGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIEWY 26542

Query: 770   KNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTE 827
             K+ K +++    S  +T   T +  ++    + G Y LK +NS G    SA   V    +
Sbjct: 26543 KDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLG----SAYAAVRVLVQ 26598

Query: 828   ENAEPPLFINRFQEIT 843
             +   PP    +F++IT
Sbjct: 26599 DKPGPPAGEIQFKKIT 26614



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G  V  +   +G P+P I W +   I+K S+  + +   +N A+L++R    E+AG +T 
Sbjct: 27213 GQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVR-FRQTENKASLIVRNARKENAGKYTL 27271

Query: 584   VAKN 587
             V  N
Sbjct: 27272 VLDN 27275



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 1/75 (1%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            +PP +I  L+N  V +G   T E +++      + WF++   I+ S   Q+T +    +L
Sbjct: 740  VPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARL 799

Query: 1164 KIYDCDLDDAGEYSC 1178
             I +   +D+G ++C
Sbjct: 800  MIREAFAEDSGRFTC 814



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 2/74 (2%)

Query: 744   MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEG 801
             ++V+ G+   L A V G P P+I W K+ K ++  A       D +S  I K    +D G
Sbjct: 21107 VVVKAGDIFKLDAHVTGRPIPSIVWTKDGKELEDTAKMEIKTLDFYSCLINKDSLRRDGG 21166

Query: 802   VYTLKAENSEGIAE 815
              YTL A N  G A+
Sbjct: 21167 AYTLTASNPGGFAK 21180



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%)

Query: 790   TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKG 848
             T     K  +  +Y  + +++    E++ V T +   +E  + P+   +F   I VK   
Sbjct: 17826 TFFMVDKCVENHIYQFRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGE 17885

Query: 849   TIKLVARVTRNPVPSITWYRNNEI-ISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
             +++L A +   P P++TW ++     +P  +I    D     L  T      D+G Y   
Sbjct: 17886 SVRLEAGLRGKPQPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKT---KRSDTGKYVVT 17942

Query: 908   ASNSAGKSSHGARVTI 923
             A+N AG  +  A VT+
Sbjct: 17943 ATNPAGSFTAYANVTV 17958



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 523   DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
             +G + +F C ++G P P +TW  +   +  S    +       +TL I  V   D G +T
Sbjct: 32150 EGDSARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHV-STTQYKSTLEISSVEYSDEGNYT 32208

Query: 583   CVAKNAAGFASSTTELIVEAPL 604
              V +N+ G   +   L +  P+
Sbjct: 32209 VVVENSEGKQEARCTLAINKPI 32230



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%)

Query: 1104  ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL--TIDGKKQ 1161
             E PP+II +L+ +      +  F  E +  + +  W+KD  ++  S+H Q+  + DG   
Sbjct: 32447 EAPPKIIQQLKAEAFEDKIRMIFVAESSLREVV--WYKDSRKLSQSSHYQIHSSADGTCC 32504

Query: 1162  KLKIYDCDLDDAGEYSCEV 1180
              L I D   DD GEYSCE+
Sbjct: 32505 -LYISDVSEDDQGEYSCEI 32522



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 8/125 (6%)

Query: 728   KTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
             K  E EP  +I  E  K+++V+ G S  L     G P P + W K +  ++   +    D
Sbjct: 25813 KEREDEPVFLISNEMRKTLVVKDGSSFTLRVPFKGKPVPHVMWNKPDVDLRVRASIDTTD 25872

Query: 786   THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
             T +   ++     D G YT+  +N  G    +A +T+     ++  PP  I   +E+T K
Sbjct: 25873 TCTSVTIEQATRDDSGKYTVTLQNVAG----TATLTLSVKVLDSPGPPAHI-EVKEVT-K 25926

Query: 846   EKGTI 850
                TI
Sbjct: 25927 SSATI 25931



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 5/121 (4%)

Query: 697   ITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPPQVIEP---LKSMIVRQGES 751
             +T +   ++ ++ V AVN    GE S   +    +   E P +  P    K++ +R G +
Sbjct: 29036 VTGLASNKKYSFRVAAVNAMGTGEFSEGSMETAPSERVEIPDIELPDELKKTVCIRAGNT 29095

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + L+  V G P P ITW K    +++       +  +  I++     D G YT++AEN  
Sbjct: 29096 LRLNVTVSGRPAPVITWRKTGIDLQSRGFIDTTENSTSLIVEKVHRYDAGKYTIEAENPS 29155

Query: 812   G 812
             G
Sbjct: 29156 G 29156



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 60/350 (17%), Positives = 138/350 (39%), Gaps = 38/350 (10%)

Query: 488   LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
             ++ K  K P+  K  +  +   P  +++L+ +   D   + F  +       ++ W++ +
Sbjct: 32428 MSPKRMKSPLTVKSPTPSKEAPPKIIQQLKAEAFEDKIRMIFVAESS---LREVVWYKDS 32484

Query: 548   AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
               +  S  +Q++   D    L I +V  +D G ++C   +  G  S T+   V       
Sbjct: 32485 RKLSQSSHYQIHSSADGTCCLYISDVSEDDQGEYSCEIISEGGAVSRTSFSFVGQVFQAI 32544

Query: 608   GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667
              +++T                 + +  + S K     +  GS+++++    A+     ++
Sbjct: 32545 YTKVTAFVAAH-----------KAVQESVSSK-----IQGGSEMVIKRESAAVSSMHESF 32588

Query: 668   LFKG---EEIVPDENISVAIESDMHM----YCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
               K    E  + + + S +  ++M        S+  +T+   +   + ++++ +   E +
Sbjct: 32589 TSKSIHMESTMQEASFSSSAMAEMKFETMSMSSMSSMTSESVYAMSSSSIMSSHSHAEET 32648

Query: 721   LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780
               +   + + +   P++    + + V  G+ + ++    G P P I W +     K LP 
Sbjct: 32649 -SVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGG---KKLPG 32704

Query: 781   KSDGD------THSIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             + D        T  +T  I+   K  D G YTLK  N  G    +  I++
Sbjct: 32705 EEDSSRFHIETTEDLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISI 32754



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%)

Query: 1571 PVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
            PV   S EDIK ++H      L+   ++     +V W  NG  +++ KE+  + +  T  
Sbjct: 4522 PVFENSLEDIKTEEHSEAKFSLIIRYVK-----KVNWLFNGKCIKSGKEFKCSKEHDTYT 4576

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            + I ++ + H  +YT EA   AG +S    L V   P  P  PV  + I    V +
Sbjct: 4577 LVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVI--PRVP--PVFRQRIQNLEVNV 4628



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 693   SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEK-EPPQVIEPL---KSMIVR 747
             +  K+ N++      + V AVN  GE+    V + ++  ++ EPP++   L   + +   
Sbjct: 16841 TTFKVINLEDGALYRFRVKAVNAAGESEPAYVPEPVRAQDRFEPPELQLDLGMPRELKAM 16900

Query: 748   QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI---LKPKKVKDEGVYT 804
              G  + + A + G P P +TW KN   V   PT+++ +T   T    ++     D G YT
Sbjct: 16901 AGTHINIMAGIKGMPFPKVTWKKNEADV---PTRAEIETSGTTTKLEMRYCNRTDCGDYT 16957

Query: 805   LKAENSEGI-AETSAVITVEEP 825
             L  EN  G    T  V+ +++P
Sbjct: 16958 LTVENPAGSKIATCTVLVLDKP 16979



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%)

Query: 807   AENSEGIAETSAVITVEEPTEENAEPPLF--INRFQEI-TVKEKGTIKLVARVTRNPVPS 863
             A N  G     +  T     ++  EPP +   + + +I TV    T  L A V   P+P+
Sbjct: 23232 ARNGAGSVSRPSESTGSVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPA 23291

Query: 864   ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             + W++ + E+ + +    +N D + + LV+ +    ID G Y    SN AG  S    V 
Sbjct: 23292 MQWFKGDVEVENSARAEIKNTDFKAV-LVVKDA-IRIDGGQYTLHLSNVAGSKSVSFNVR 23349

Query: 923   I 923
             +
Sbjct: 23350 V 23350



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 37/280 (13%)

Query: 632   IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             I P+F        V  G D+ +E      P P I W+  G+ +     ++V+  +     
Sbjct: 23945 IEPSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTAT---- 24000

Query: 692   CSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
              +VLKI    +   G YT+ A N  G  +  + I++  K G    P  I+ + +  V   
Sbjct: 24001 STVLKIKEANREDSGKYTITATNNIGTVTEEVAIIILDKPGPPTGPVKIDEVSATYV--- 24057

Query: 750   ESVILSAQVVGNPRPTIT-WCKNNKPV--KALPTKSDGDTHSITI----LKPKKVKDEGV 802
                     V+    P  T  C+ N  V  K   T ++  T S TI    +K  K+K    
Sbjct: 24058 --------VISWEPPVYTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSE 24109

Query: 803   YTLK--AENSEGIAET--SAVITVEEPTEENAEPPL-FINRF--QEITVKEK------GT 849
             Y  +  AEN  G + +  S  + V  P  E A P   F++      +T++ K      G+
Sbjct: 24110 YQFRVFAENRYGKSGSIDSTPVVVSYPFTEPAAPGAPFVSSVTKDHMTIEWKPPSNNGGS 24169

Query: 850   IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
               +   + R    SI W + N+++     +  N   E IE
Sbjct: 24170 PIIGYHLERKEKNSILWTKLNKLLITDTRLRTNGLEEGIE 24209



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%)

Query: 501   PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559
             P S+    AP F ++LR       +   F  +V G+P+P + W++    I+      ++ 
Sbjct: 30552 PKSDTALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQ 30611

Query: 560   YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
                     LVI      DA  +   A N  G  S++  L VE P
Sbjct: 30612 EFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVP 30655



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            A + GIP PE+ W+ N   ++  K   Y+      T+ + I +    H+ +YT +A N  
Sbjct: 3265 ACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIR 3324

Query: 1652 GTSSVEVTLKVYDKPSK 1668
            G ++    L V ++ ++
Sbjct: 3325 GEAACSANLAVTEEVTR 3341



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 5/130 (3%)

Query: 474   LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHT---PDGSTVQFE 530
             L++   Y+ +  K +NE  +  P      +++Q + P    K  P  +    +G+TV+  
Sbjct: 19616 LVEGKEYS-FRVKAINESAEGPPTELTILAKDQIVPPNCDLKGLPDSSYVAKEGTTVRLN 19674

Query: 531   CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
               + G P P + W +    +  S    +     N   L+IR+    DAG FT + +N+AG
Sbjct: 19675 IPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNTV-LLIRDCHRGDAGKFTIILRNSAG 19733

Query: 591   FASSTTELIV 600
                +  ++ V
Sbjct: 19734 TKEAAIDIKV 19743



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 3/67 (4%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+T++    V G P P ITW R+T I   S+ F      +N  +L++ +V   DAG +T 
Sbjct: 29093 GNTLRLNVTVSGRPAPVITW-RKTGIDLQSRGF--IDTTENSTSLIVEKVHRYDAGKYTI 29149

Query: 584   VAKNAAG 590
              A+N +G
Sbjct: 29150 EAENPSG 29156



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 2/116 (1%)

Query: 1407  TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             T  S  +   ++     ++    +K  T + +S+ ++ + S Y   + ++  +     +E
Sbjct: 32589 TSKSIHMESTMQEASFSSSAMAEMKFETMSMSSMSSMTSESVYAMSSSSI--MSSHSHAE 32646

Query: 1467  TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
              T     +   +  +P +E   ++I+ E  + + + C F G P P + W R GKKL
Sbjct: 32647 ETSVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKKL 32702



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 2/95 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV K        G   +F+C + G     + W +    I    D      D N   L 
Sbjct: 4710 PEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAIS-LDDHYKESSDKNRYFLE 4768

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
            I  +   D GT+ C A N+ G A+  TEL +V+ P
Sbjct: 4769 ILNLQHSDQGTYLCKASNSVGTATCCTELRVVDKP 4803



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 8/144 (5%)

Query: 693   SVLKITNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKS-MIVR 747
             +V  +T+ K++Q   + V A N  G +    S P++      ++    +   L+S + V+
Sbjct: 14357 TVKGLTHEKQYQ---FRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVK 14413

Query: 748   QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             +GE + L A + G P P ITW +NN  +   P K   +       + ++ K+EG    +A
Sbjct: 14414 RGEEIRLDANISGFPYPQITWMRNNATIWPEPLKKRPERPIKKKKEKEEKKEEGAEKKEA 14473

Query: 808   ENSEGIAETSAVITVEEPTEENAE 831
             +  +   +  A    +E  EE  E
Sbjct: 14474 DAEKKEEDKEAKEEDKEKKEEKKE 14497



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 3/123 (2%)

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
             +F+  T   + ++R  + ++P++ + K         ++ ++ +IV+ G ++ L A + G 
Sbjct: 17148 RFRVKTENAIGLSRP-DTTVPVLCQEKLVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGL 17206

Query: 762   PRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819
             P PT  W  + + +K+   TK D D  S  +      ++  G+Y L   NS G    S  
Sbjct: 17207 PVPTAKWVIDGEEIKSEGNTKIDTDNFSTVLSIADCTRNHTGIYILTVSNSAGSKTVSLN 17266

Query: 820   ITV 822
             +TV
Sbjct: 17267 VTV 17269



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 6/114 (5%)

Query: 632   IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             I PT   K     V  G D+ +E R+   P+P I W   G  +     ++VA ++  H  
Sbjct: 22863 IEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVA-DTAHH-- 22919

Query: 692   CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKS 743
              + L I +  +   G Y +V  N  G  EA++ I++  K G    P  I+ + +
Sbjct: 22920 -TTLTIKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSA 22972



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 6/144 (4%)

Query: 784   GDTHSITILKPKKVKD-EGVYTLKAENSEGIAETS---AVITVEEPTEENAEPPLFINRF 839
             G T S+ ++    V++ E  + +KA+N  GI++     A + ++EP  E       I++ 
Sbjct: 28228 GQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSSIDK- 28286

Query: 840   QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
             Q IT K   +  +   ++  P P +TW      +  ++ ++     +   L++ +     
Sbjct: 28287 QLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDA-KRG 28345

Query: 900   DSGDYKCVASNSAGKSSHGARVTI 923
             DSG Y     N+AG  +    V +
Sbjct: 28346 DSGKYYLTLENAAGSKTFTVTVIV 28369



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 1/100 (1%)

Query: 630   EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
             +G+ P     P+   V+ G  + + C     P P I W  +G + +P E  S     +  
Sbjct: 32658 QGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEW-SRGGKKLPGEEDSSRFHIETT 32716

Query: 690   MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
                + L IT VK+   G YT+   N  G     + + I++
Sbjct: 32717 EDLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISIRS 32756



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 39/161 (24%), Positives = 63/161 (39%), Gaps = 9/161 (5%)

Query: 1226 DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK--LK 1280
            D  W+   + V+ D     ++ +   +++I+      D  E+T V  +   K+T    L 
Sbjct: 1259 DTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKTTVSMTLT 1318

Query: 1281 VEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK--KCKHTKP 1336
            VE  E    P+ ++  +   +K GS V L V     P P+  W+ NS II   K  H K 
Sbjct: 1319 VEAKENLVRPQFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKI 1378

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
                  A   I +   +D+  Y     N  G       V +
Sbjct: 1379 EGAKGQAHFQIPQTSGSDSAWYTATAINKAGRDTTRCRVNV 1419



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E++   P+F   L    T + S  +F   +  Y + ++ W      IK  ++F+   + D
Sbjct: 4516 EDKEGYPVFENSLEDIKTEEHSEAKFSLIIR-YVK-KVNWLFNGKCIKSGKEFKCSKEHD 4573

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
               TLVI +V  +  G +TC A   AG  S+++ L V
Sbjct: 4574 TY-TLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTV 4609



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 15/145 (10%)

Query: 693   SVLKITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGE-KEPPQVIEPLKS---MIVR 747
             +V  I N+ + ++  + ++AVN  GE+   P   +++  + K  P++   + +   + VR
Sbjct: 15537 TVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVRIEDIKTAPKIFMDISADELLCVR 15596

Query: 748   QGESVILSAQVVGNPRPTITW-----CKNNKP--VKALPTKS---DGDTHSITILKPKKV 797
              G    + A + G P P +TW      K  K   +  LP  S     DT S+  +     
Sbjct: 15597 AGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTSVVTVPVSLR 15656

Query: 798   KDEGVYTLKAENSEGIAETSAVITV 822
                G YT+ A+N  G    +  + V
Sbjct: 15657 SHSGRYTITAKNKSGQKHVNVRVNV 15681



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 23/91 (25%), Positives = 40/91 (43%)

Query: 510   PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
             P+ ++ +   H   G  V  +  + G P P +TW +   II  +   Q+       + + 
Sbjct: 30661 PLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVF 30720

Query: 570   IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             ++ V  +D+G +   AKN  G    T EL V
Sbjct: 30721 LKGVQRKDSGYYIICAKNRFGMDKQTVELDV 30751



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 5/114 (4%)

Query: 814   AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
             +ETSA ++V++     +     + +   + V E  + + V  +   P P++TW      +
Sbjct: 32120 SETSAEVSVKKIKATLSAK--ILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTV 32177

Query: 874   SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
               S  I  +       L I++V+   D G+Y  V  NS GK    AR T+ + K
Sbjct: 32178 VSSHRIHVSTTQYKSTLEISSVEYS-DEGNYTVVVENSEGKQE--ARCTLAINK 32228



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 831   EPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             EPP     F++  V   G T  + +R T  P P+I W++N+E +  +E I        + 
Sbjct: 16485 EPPNLDLEFRDKLVVRVGETCIIQSRYTGKPEPTIKWFKNDEELQANEEIALTTAKNRLS 16544

Query: 890   LVITNVDSEIDSGDYKCVASNSAG 913
             L I     +  SG Y  V  NS G
Sbjct: 16545 LTIEKAKRD-HSGKYMVVLENSIG 16567



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 10/158 (6%)

Query: 785   DTHSITILKPKKVKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPP---LFINRF 839
             D+   T  K   ++D  +Y   +KA N+ G +E  A +      ++  EPP   L +   
Sbjct: 16836 DSCPSTTFKVINLEDGALYRFRVKAVNAAGESEP-AYVPEPVRAQDRFEPPELQLDLGMP 16894

Query: 840   QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
             +E+       I ++A +   P P +TW +N   +     I  +     +E+   N     
Sbjct: 16895 RELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETSGTTTKLEMRYCN---RT 16951

Query: 900   DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
             D GDY     N AG       V + ++K   V+HL+ S
Sbjct: 16952 DCGDYTLTVENPAGSKIATCTVLV-LDKPGPVQHLRVS 16988



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 696   KITNVKKFQEGTYTVVAVNREGEASL---PIVLKIKTGEKEPPQVIEP--LKSMIVRQGE 750
             ++T ++  +E  + V AVN  G+      P +++       P   I+    ++ IV+ G 
Sbjct: 27946 RVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGG 28005

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
             +V L     G P P  TW K +  +  +   +  DT S   ++     D G YTL  EN+
Sbjct: 28006 TVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENN 28065

Query: 811   EG 812
              G
Sbjct: 28066 SG 28067



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV   +P     G+TV F   V+G    ++ WFR +  I   +  ++    D  A L 
Sbjct: 6937 PSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGD-TAILE 6995

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +  +    AG +TC   N AG  +    L V+
Sbjct: 6996 LHNIDKSHAGEYTCQIINDAGKENCPVNLFVK 7027



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%)

Query: 797   VKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKL 852
             +K+ G+Y   ++A N+ G+ E   V  V E  +    P + ++    ++I V   G I++
Sbjct: 16153 LKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRI 16212

Query: 853   VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
             +A V+  P P I W R++  + P E   +     +  LVI +   +   G Y   A N+ 
Sbjct: 16213 LAYVSGKPAPEIIWNRDDAEL-PKEAAVET-TSISSALVIKSCLRQ-HQGIYTLTAKNAG 16269

Query: 913   GKSSHGARVTI 923
             G+      V +
Sbjct: 16270 GERKKAVIVEV 16280



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 32/136 (23%), Positives = 58/136 (42%), Gaps = 6/136 (4%)

Query: 677   DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
             D+  S ++  D+ +  + LK     +F+      +  +   EA    + ++K     P  
Sbjct: 18515 DKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEG--IFEVKEQLMAPKI 18572

Query: 737   VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
             ++  +  +  R G  +I+ A V G P P   W + +  +          T + ++L  K 
Sbjct: 18573 IVSDV--VTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPTTSLLMVKD 18630

Query: 797   V--KDEGVYTLKAENS 810
             V  KD G Y+L AENS
Sbjct: 18631 VTRKDSGYYSLSAENS 18646



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 5/99 (5%)

Query: 1091  LRDESCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSE 1145
             L++   +AEV+V +    L  +I+T+  +  V++G+ A F  ++    A  V W  +G  
Sbjct: 32117 LKESETSAEVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRT 32176

Query: 1146  IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
             +  S+ I ++    K  L+I   +  D G Y+  V NS+
Sbjct: 32177 VVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSE 32215



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 15/50 (30%), Positives = 26/50 (52%)

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            + E +  + +   P+K+        +   C  GG P PK+ WY+DGK++K
Sbjct: 1067 VAEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWYKDGKRIK 1116



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 34/181 (18%), Positives = 74/181 (40%), Gaps = 11/181 (6%)

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529
            KV     +++P + + +++ T    +++   C   G P P+  W+++G  L+ +   Y  
Sbjct: 1841 KVALSPSMEAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWY 1900

Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN--EDIKQKH 1584
               ++                    A N  GE  +   + +Q K V++ +   ED   K 
Sbjct: 1901 WPEDHVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKE 1960

Query: 1585 KVGDEWLVTAVIEGIPP-PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            K   + +VT   E   P  +V W KN  ++ +  +Y + +  K   + +  +     ++Y
Sbjct: 1961 K---DTMVTFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQDDAEY 2017

Query: 1644 T 1644
            +
Sbjct: 2018 S 2018



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 1/97 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            EQ + P F++ L       G  VQ  C++ G     + W +    +      ++  D+++
Sbjct: 6297 EQIIPPSFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKDGTKLSGRTKHKILQDENS 6356

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            V+ L I  +   D GT+TC   N AG    +  L V+
Sbjct: 6357 VS-LDIECLEKADTGTYTCKLANKAGSCECSGTLRVK 6392



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 504  EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            +E+ + P F +K        +G  V+ E +V G     + W++    I  S  + + +  
Sbjct: 7405 KERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKS 7464

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             ++A L I++    D+GT+ C A N AG AS    + + A
Sbjct: 7465 -SLAVLCIKKSQLSDSGTYVCKATNEAGTASFEVSVHITA 7503



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 12/137 (8%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQVIEPLKSMIVRQGESVIL 754
             I ++K+  E  + V AVN  G AS P V    I   ++     I+  +++   +G  V +
Sbjct: 15851 IEDLKEGGEYEFRVKAVNEAG-ASRPSVTAGPIVIKDQTCAPSIDLREALEGAEGFDVNI 15909

Query: 755   SAQVVGNPRPTITWCK--NNKPVKALPTKSD-------GDTHSITILKPKKVKDEGVYTL 805
              A++ G P P++ W K   +KP   +P + D        D      ++  K  D  +YTL
Sbjct: 15910 VARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKRDDSAMYTL 15969

Query: 806   KAENSEGIAETSAVITV 822
              A NS G A  S  +++
Sbjct: 15970 TATNSLGTATKSIKLSI 15986



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             GS +  +  V G P P++ W +    + P + + + Y     A  +I+     D G +  
Sbjct: 28694 GSDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYSLTYTSTR-AMAIIKSCDRNDTGRYIL 28752

Query: 584   VAKNAAGFASSTTEL-IVEAP 603
               KNA+G  +S   + +++ P
Sbjct: 28753 TVKNASGIKTSAVNVKVLDTP 28773



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%)

Query: 757   QVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILK-PKKVKDEGVYTLKA-ENSEGI 813
             Q V +P  +    K+  P+K+  P  S     S T LK P+  + +   T+K+ E     
Sbjct: 32371 QGVKSPIASPPRVKSPPPIKSPEPIASPLRVKSPTGLKSPEPQRAKSPPTVKSPEPIMSP 32430

Query: 814   AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
                 + +TV+ PT     PP  I + +    ++K  I+++  V  + +  + WY+++  +
Sbjct: 32431 KRMKSPLTVKSPTPSKEAPPKIIQQLKAEAFEDK--IRMIF-VAESSLREVVWYKDSRKL 32487

Query: 874   SPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             S S    I  + DG    L I++V SE D G+Y C   +  G  S
Sbjct: 32488 SQSSHYQIHSSADG-TCCLYISDV-SEDDQGEYSCEIISEGGAVS 32530



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 512   FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
             F + L  +   + +T + EC+V    + ++ WFR    I+ ++ + M  D      LVI 
Sbjct: 12003 FTKPLEDQTVEEEATAELECEVSK-EKAEVRWFRDGQEIRKTKKYDMVADGCK-RKLVIH 12060

Query: 572   EVFPEDAGTFTCVAKN 587
             +   +D+ T+TC AK+
Sbjct: 12061 DCTLDDSKTYTCDAKH 12076



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+ ++    + G P P++ W +   ++KP     +     + +TL I +   +D  T+  
Sbjct: 13420 GTKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGH-STLSIAKTKRDDTATYII 13478

Query: 584   VAKNAAGFASSTTEL-IVEAP 603
              A N++G A++T ++ I++ P
Sbjct: 13479 EAVNSSGRATATVDVNILDKP 13499



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 8/105 (7%)

Query: 840   QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDS 897
             + +TV+    I +V  V   P P ITW +   I+   +   +T NF    +++ I    +
Sbjct: 17584 ERVTVRVGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNF--PVVQMRIKEA-T 17640

Query: 898   EIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETE 941
               D G Y   A N AG++S  A +T++V ++    ++L+ +Y T+
Sbjct: 17641 RADHGKYVLKAVNEAGEAS--ATITVNVLDRPGHCQNLKMTYVTK 17683



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 1/110 (0%)

Query: 491   KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550
             K D  P+     +++ ++ P F           G  ++ E   +G P P+I W +    +
Sbjct: 23928 KSDPRPLASPVIAKDVTIEPSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQAL 23987

Query: 551   KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             K +    +         L I+E   ED+G +T  A N  G  +    +I+
Sbjct: 23988 KETTRLNV-SSTATSTVLKIKEANREDSGKYTITATNNIGTVTEEVAIII 24036



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 6/120 (5%)

Query: 696   KITNVKKFQEGTYTVVAVNREGEASL----PIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             ++T +K+  E  + V A N +G +      PI +K      E   +  P   + VR G++
Sbjct: 27156 EVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEANLIDYPNGELSVRIGQN 27215

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--SITILKPKKVKDEGVYTLKAEN 809
             V +     G P+P I W K++  +K         T   +  I++  + ++ G YTL  +N
Sbjct: 27216 VNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKENAGKYTLVLDN 27275



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTH 787
            EK  P+++   + + V +GE+     +V G P P + W  N    +  K      DG  H
Sbjct: 1609 EKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRLHYDG-IH 1667

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             + I   K   D G   + AEN EG AE +  + +++
Sbjct: 1668 YLEITDCKSY-DSGDVRVLAENPEGTAEHTVKLEIQQ 1703



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 9/135 (6%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQVIEPLKS---MIVRQGE 750
             IT + + Q   + V+A N  G  S+P           E E P V    +    +IV+ G+
Sbjct: 24299 ITGLHEEQRYEFRVIARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGD 24358

Query: 751   SVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
             S  + + + G P P I W K+ K +  A P      T + T+L  K     D G + L  
Sbjct: 24359 SFSIDSDIAGKPLPDIVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSL 24418

Query: 808   ENSEGIAETSAVITV 822
              N  G  +    + V
Sbjct: 24419 SNVGGTKQVPINVKV 24433



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 11/135 (8%)

Query: 795   KKVKDEGVYTLK--AENSEGIAE----TSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
             KK+K+   Y  +  A N EG  E      +VI  E+   E  E  L  +  + +TV+   
Sbjct: 24701 KKLKENAEYNFRICAVNIEGAGEHVDVPGSVIAAEKL--EAPEIELDADLRKCVTVRASA 24758

Query: 849   TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
             T++L   +   P P + W + +  +     I     G    LVI NV +  D+G Y    
Sbjct: 24759 TLRLFVTIRGRPEPEVKWKKADGTLPERAQI--EVTGSYTGLVIDNV-NRFDTGKYVLTL 24815

Query: 909   SNSAGKSSHGARVTI 923
              N+ G  S    V +
Sbjct: 24816 ENNIGSKSAFVNVKV 24830



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 2/87 (2%)

Query: 827   EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
             +E+  P +     + +T+K    IKL   ++  PVP +TWY++ + +           G 
Sbjct: 27586 DESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGS 27645

Query: 887   NIELVITNVDSEIDSGDYKCVASNSAG 913
             +  L I + D     G Y   A NS+G
Sbjct: 27646 S-SLFIRDADRN-HRGIYTVEAKNSSG 27670



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G++   +  + G P P++TW  +   +K +    +    D   TL++++    D+G +  
Sbjct: 28294 GNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDR-TTLLVKDAKRGDSGKYYL 28352

Query: 584   VAKNAAGFASSTTELIV 600
               +NAAG  + T  +IV
Sbjct: 28353 TLENAAGSKTFTVTVIV 28369



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 11/151 (7%)

Query: 814   AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
             +E    +  ++P   +  P + + R +   V      K    V   P  +I W+ N + I
Sbjct: 31901 SERKYQVVTQQPFSLDHAPRITV-RMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQI 31959

Query: 874   SPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
               S      N  G  + L I +  +E D+G Y+ + +NS G++S  A  T+DV    F  
Sbjct: 31960 QESHKYQFTNMSGV-LSLQINDCQAE-DTGTYRALCTNSKGEASDYA--TLDVSGGAFTT 32015

Query: 933   HLQKSYETEEGKTVILECQTSHTVSTKWYHN 963
             +  +  + EE  T I+   T     T +YH+
Sbjct: 32016 YSSRRRD-EEAPTQIVPDIT----KTDYYHS 32041



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 8/130 (6%)

Query: 798   KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVAR 855
             + E  + + A+N  G+   + V     P E +  P + ++    + ++V+    I+L A 
Sbjct: 18240 RQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCPIRLFAT 18299

Query: 856   VTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVASNSAG 913
             +   P P +TW R    I     I +      + +  ++    S  DSG Y    SN +G
Sbjct: 18300 IRGRPAPKVTWKR----IGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSG 18355

Query: 914   KSSHGARVTI 923
             + +   RV +
Sbjct: 18356 EKAVFVRVKV 18365



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 21/77 (27%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+ V  E +V G P P++ W +  A +K ++  +M     ++ +L +  V  +++G +T 
Sbjct: 18979 GANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHL-SLELFSVTRKESGEYTI 19037

Query: 584   VAKNAAGFASSTTELIV 600
              A+N +G  S+  +L V
Sbjct: 19038 TAENPSGSKSANIKLKV 19054



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 6/115 (5%)

Query: 803   YTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTI-KLVARVTRN 859
             + + A NS G +++ S    V    ++  EP +  +  F  + V + G I KL A VT  
Sbjct: 21065 FRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTGR 21124

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS-EIDSGDYKCVASNSAG 913
             P+PSI W ++ + +   +T        +    + N DS   D G Y   ASN  G
Sbjct: 21125 PIPSIVWTKDGKEL--EDTAKMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGG 21177



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 7/125 (5%)

Query: 803   YTLKAENSEGIAE----TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
             Y ++A N  G ++    T  ++ V+   +E  E  L       +T K    I+L A +T 
Sbjct: 13374 YRVRALNKLGASKPCKSTDEILAVDP--KEPPEIQLDAKLLAGLTAKAGTKIELPADITG 13431

Query: 859   NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
              P P + W + + ++ P + IT +    +  L I     + D+  Y   A NS+G+++  
Sbjct: 13432 KPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKRD-DTATYIIEAVNSSGRATAT 13490

Query: 919   ARVTI 923
               V I
Sbjct: 13491 VDVNI 13495



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 648   GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
             G+ I L   +   PEP + W      + PD+ I++    D     S L I   K+    T
Sbjct: 13420 GTKIELPADITGKPEPKVKWTKADLVLKPDDRITI----DTKPGHSTLSIAKTKRDDTAT 13475

Query: 708   YTVVAVNREGEASLPIVLKI 727
             Y + AVN  G A+  + + I
Sbjct: 13476 YIIEAVNSSGRATATVDVNI 13495



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 9/148 (6%)

Query: 672   EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG---EASLPIVLKIK 728
             E  +P+E+    +     +  +   ITN+ + QE    + A+N EG    AS+P   K +
Sbjct: 21429 ETCLPEEDEWTIVTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEPASVPGSPKAE 21488

Query: 729   TGEKEPP-QVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786
                  P  ++   L+ ++ +R   ++ L   V G P P I W +     + L   S   T
Sbjct: 21489 DRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRWSREKG--EPLDRASIEIT 21546

Query: 787   HSITILKPKKVK--DEGVYTLKAENSEG 812
              S T L  + V   D G Y L  ENS G
Sbjct: 21547 PSFTTLLIENVDRFDGGKYMLTVENSSG 21574



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 7/112 (6%)

Query: 805   LKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNPV 861
             + A N EG+ E ++V       E+   PP   L  +  + + ++   T++L   V   P 
Sbjct: 21467 ISALNCEGVGEPASV-PGSPKAEDRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPA 21525

Query: 862   PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             P I W R  E   P +  +         L+I NVD   D G Y     NS+G
Sbjct: 21526 PEIRWSR--EKGEPLDRASIEITPSFTTLLIENVD-RFDGGKYMLTVENSSG 21574



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 8/116 (6%)

Query: 712   AVNREGEASLPIVLKIKTGEKEPPQ---VIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
             +V+R  E++  +  K    E EPP      E  + + V  G++  L A V+G P P + W
Sbjct: 23238 SVSRPSESTGSVTAK---DEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQW 23294

Query: 769   CKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
              K +  V+  A     + D  ++ ++K     D G YTL   N  G    S  + V
Sbjct: 23295 FKGDVEVENSARAEIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSKSVSFNVRV 23350



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             GS ++ E  + G P P+++  +   ++K +  F      D++  + +RE    DAG +  
Sbjct: 26126 GSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLI-IYLRESVASDAGRYDI 26184

Query: 584   VAKNAAGFASSTTELIV 600
              A N+ G   S   ++V
Sbjct: 26185 TASNSNGTTKSFVNVVV 26201



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 502   TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYY 560
             T +E  +  I  E  +      G  ++  C + G P PQ+TW++    + K   D     
Sbjct: 27584 TKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVI 27643

Query: 561   DDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
                  ++L IR+      G +T  AKN++G
Sbjct: 27644 GS---SSLFIRDADRNHRGIYTVEAKNSSG 27670



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 17/172 (9%)

Query: 1136  LVRWFKDGSEIQFSNHIQLTID---GKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAI 1188
             +V+W+K+G EI  ++  ++ +    G   +L I + D +DA  Y      ++G+   +  
Sbjct: 30591 VVKWYKNGKEI-LADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMN 30649

Query: 1189  LTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLD---VTWYKKKSVIEDTEKFTL 1244
             L VE P+ I   L L     V A     +T++IP        VTW K + +I +T    +
Sbjct: 30650 LDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQV 30709

Query: 1245  ISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIV 1291
             I      +L+  K  +     Y  +         K T +L V  V  PPK V
Sbjct: 30710 IITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVELDVADVPDPPKDV 30761



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 47/196 (23%), Positives = 72/196 (36%), Gaps = 20/196 (10%)

Query: 1201  RLPEFILVPANTDAYL--------TVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKR 1251
             R PEF L   N  AY+        T+ +  E   VTW K    I+ D +K+T  SD    
Sbjct: 31320 RPPEFTLPLFNRSAYIGEDVRFGVTITVHPEP-SVTWLKAGHRIKPDPKKYTFTSDKGLY 31378

Query: 1252  TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR---------G 1302
              L+I      D  EYT V  +       K  +   P  + +       KR         G
Sbjct: 31379 QLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEG 31438

Query: 1303  SDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
               V   +     P P  +W  N K ++ + +      D     L I++    D+G Y++ 
Sbjct: 31439 QSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVT 31498

Query: 1362  LENNCGHADVEMNVTI 1377
               N  G A  +  + +
Sbjct: 31499 ATNTAGSASCQATLKV 31514



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 1/127 (0%)

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            A ST +L V     PP  +   +   +++GS V L V     P P  ++      I+   
Sbjct: 89   ATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSA 148

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSPPGKPNILE 1391
              +   D    SL I +    D+G Y +   N+ G A     + +  ++ + P K +   
Sbjct: 149  DFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSGRATSTAELLVQGEEEAVPAKKSKTI 208

Query: 1392 IDSSSIN 1398
            I +S I+
Sbjct: 209  ISASQIS 215



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 3/98 (3%)

Query: 1006 TSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKY 1063
            T+ +LV  ET P  FI++LQ   V++     L+V +    A VV + R+G  I+   + +
Sbjct: 92   TAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSAD-F 150

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
               + G +  L I      D G YS    + S  A  T
Sbjct: 151  QIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSGRATST 188



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 7/98 (7%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V  GS I L   +  +P P   W+  GEEI  + N  +    D   + +VL I +  +  
Sbjct: 17191 VKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKI----DTDNFSTVLSIADCTRNH 17246

Query: 705   EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIE 739
              G Y +   N  G  ++ +   VL +      P  ++E
Sbjct: 17247 TGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILE 17284



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 742   KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--D 799
             K++++R G ++ +   + G P P  TW K N  +K         T   T L  + +   D
Sbjct: 19372 KALVLRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYD 19431

Query: 800   EGVYTLKAENSEGIAETSAVITV 822
              G Y L  ENS G    + V+ V
Sbjct: 19432 AGKYVLTLENSSGTKSYTIVVKV 19454



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 7/125 (5%)

Query: 704   QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE----PLKSMIVRQGESVILSAQVV 759
             +E ++ V A+N   E   P  L I   ++  P   +    P  S + ++G +V L+  + 
Sbjct: 19620 KEYSFRVKAINESAEGP-PTELTILAKDQIVPPNCDLKGLPDSSYVAKEGTTVRLNIPIT 19678

Query: 760   GNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
             G P P + W K +  +      +     T+++ +++     D G +T+   NS G  E +
Sbjct: 19679 GIPAPAVIWKKGDVTLSDSGRISVESTTTNTVLLIRDCHRGDAGKFTIILRNSAGTKEAA 19738

Query: 818   AVITV 822
               I V
Sbjct: 19739 IDIKV 19743



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 53/232 (22%), Positives = 93/232 (40%), Gaps = 26/232 (11%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQGES 751
             +  + + +E ++ + A N +G  S P  L +    K+   VI P   ++     V  G+ 
Sbjct: 21744 VVGLTQGEEYSFRISATNEKG-ISDPRPLSVPVIAKDV--VIAPAFKLLFSTFSVLAGDD 21800

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAEN 809
             + +    V  P+  + W K+   +K     +    + H   +LK     D G YT+K  N
Sbjct: 21801 LKIDVPYVAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITN 21860

Query: 810   SEGIAETSA-VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
             S G A     VI +++P      PP    + +E+T         V    + P        
Sbjct: 21861 SAGEATADINVIVLDKP-----GPPTGPIKIEEVTADS------VTLSWQPPEYEGGCSI 21909

Query: 869   NNEIISPSETITQNFDGENIELVITNVD-SEIDSG---DYKCVASNSAGKSS 916
             NN I+   +T T N+   +  +  T    + + +G    ++  A N  GKSS
Sbjct: 21910 NNYIVEKRDTSTTNWQIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKSS 21961



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 10/189 (5%)

Query: 640   PKAQYVDEGSDILLECRLVAIPEPDI-AWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
             PK  YV   S +L   + +     +I +++ +  E+  DE +     S +    +  +  
Sbjct: 22480 PKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITE--TRFEAK 22537

Query: 699   NVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGESVI 753
              + +  E  + + AVN+ G    A +P  + I+   + P   ++  L+ MI VR G S+ 
Sbjct: 22538 KLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEAPDIDLDADLRKMITVRAGGSLR 22597

Query: 754   LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             L   + G P P + W K    +          + +  +++     D G YTL  EN+ G 
Sbjct: 22598 LFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLTLENASG- 22656

Query: 814   AETSAVITV 822
                SA I+V
Sbjct: 22657 -TKSAFISV 22664



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 12/134 (8%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGT-IKLVARVTRNP 860
             + + A N  G +E S   +     +    P +F++    E+     GT  K+ A +T  P
Sbjct: 15552 FRIIAVNEIGESEPSPRTSEVRIEDIKTAPKIFMDISADELLCVRAGTPFKIPATITGRP 15611

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
              P +TW    E    ++T  ++       L I  VDS+++S D   V +      SH  R
Sbjct: 15612 APKVTW----EFDGKAKTEKKD------RLHILPVDSQVESTDTTSVVTVPVSLRSHSGR 15661

Query: 921   VTIDVEKVTFVKHL 934
              TI  +  +  KH+
Sbjct: 15662 YTITAKNKSGQKHV 15675



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 7/99 (7%)

Query: 632   IPPTFSKK--PKAQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
             +PP    K  P + YV  EG+ + L   +  IP P + W  KG+  + D    +++ES  
Sbjct: 19649 VPPNCDLKGLPDSSYVAKEGTTVRLNIPITGIPAPAVIWK-KGDVTLSDSG-RISVESTT 19706

Query: 689   HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
                 +VL I +  +   G +T++  N  G     I +K+
Sbjct: 19707 TN--TVLLIRDCHRGDAGKFTIILRNSAGTKEAAIDIKV 19743



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 25/124 (20%), Positives = 54/124 (43%), Gaps = 2/124 (1%)

Query: 800   EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             E ++ + A N +G ++   ++      ++ A  P    +    +V+    +K+ AR++ +
Sbjct: 22833 EYIFRVIAVNDKGKSDPR-LLASPVVAKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGH 22891

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             P P+ITW ++   +  +  +       +  L I +   E D G Y  V +N  G+     
Sbjct: 22892 PKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATRE-DGGMYNIVVANVLGQQEATV 22950

Query: 920   RVTI 923
              + I
Sbjct: 22951 EIII 22954



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 5/97 (5%)

Query: 632   IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             IP    +  K+  +  G +I L C +   P P + W   G+E+  D+   + ++    + 
Sbjct: 27590 IPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEV--DK---MLVDITTVIG 27644

Query: 692   CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
              S L I +  +   G YTV A N  G   + ++++++
Sbjct: 27645 SSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQ 27681



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
            + KP I +  E I+     G+       + G P P+V WY NG  +   K + +   +  
Sbjct: 1610 KSKPEIVLLPEPIRVFE--GETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRL-HYDGI 1666

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
              + I + K   S    + A N  GT+   V L++  K
Sbjct: 1667 HYLEITDCKSYDSGDVRVLAENPEGTAEHTVKLEIQQK 1704



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVAI-ESDMHMYCSVLKITNVK 701
             V +   I +   +  +P P I WL K + ++  P E +     E D     + L I  V 
Sbjct: 15180 VRKNEPIEMPAEVTGLPMPKIEWL-KDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVT 15238

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
             +  +GTYTV A NR G  S  + +++      P  V
Sbjct: 15239 RLDKGTYTVTASNRLGTLSHSVTVEVLDRPTPPRNV 15274



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G T   E  V G P P + WF+    ++ S   ++  + D  A LV+++    D G +T 
Sbjct: 23275 GDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEI-KNTDFKAVLVVKDAIRIDGGQYTL 23333

Query: 584   VAKNAAGFAS 593
                N AG  S
Sbjct: 23334 HLSNVAGSKS 23343



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 5/105 (4%)

Query: 727   IKTGEKEPPQVIEPLKSMIV--RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784
             IK    EP   +  +   ++  + G S  +   + G P P +TW      +K     S  
Sbjct: 28270 IKEPRIEPTADLSSIDKQLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIK 28329

Query: 785   DTHSITILKPKKVK--DEGVYTLKAENSEGIAE-TSAVITVEEPT 826
              +   T L  K  K  D G Y L  EN+ G    T  VI +  PT
Sbjct: 28330 ISKDRTTLLVKDAKRGDSGKYYLTLENAAGSKTFTVTVIVIGRPT 28374



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/107 (21%), Positives = 44/107 (41%), Gaps = 6/107 (5%)

Query: 1558  EVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             +V T     +   P IT+      + H+V  G     T  ++  P   + W+ NG +++ 
Sbjct: 31906 QVVTQQPFSLDHAPRITVR----MRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQE 31961

Query: 1616  DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
               +Y  T       ++I + +   +  Y    +N+ G +S   TL V
Sbjct: 31962 SHKYQFTNMSGVLSLQINDCQAEDTGTYRALCTNSKGEASDYATLDV 32008



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/128 (19%), Positives = 51/128 (39%), Gaps = 3/128 (2%)

Query: 1256  RKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
             R  T +        L +++++ ++ V+ ++     KI+       +  G     + D   
Sbjct: 32103 RHTTSEKHVSSESKLKESETSAEVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDG 32162

Query: 1314  FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
              P P   W+   + +        S     ++L I  VE +D G Y + +EN+ G  +   
Sbjct: 32163 EPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARC 32222

Query: 1374  NVTILDKP 1381
              + I +KP
Sbjct: 32223 TLAI-NKP 32229



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 1013  KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
             KE  P+ I++L+    ++K   I   E  S   +VVW +D   +    +           
Sbjct: 32446 KEAPPKIIQQLKAEAFEDKIRMIFVAE--SSLREVVWYKDSRKLSQSSHYQIHSSADGTC 32503

Query: 1073  KLYIRNTSVHDEGEYSCILRDE 1094
              LYI + S  D+GEYSC +  E
Sbjct: 32504 CLYISDVSEDDQGEYSCEIISE 32525



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPEDAGTF 581
             G  +   C   G P P I W R    +   +D   ++ +  +++ TL+I  V   DAG +
Sbjct: 32676 GKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTEDLTTLIITGVKETDAGAY 32735

Query: 582   TCVAKNAAGFASSTTELIVEA 602
             T    N  G   +T  + + +
Sbjct: 32736 TLKLSNEHGSDLATVTISIRS 32756


>UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 11202

 Score =  311 bits (764), Expect = 1e-82
 Identities = 330/1441 (22%), Positives = 581/1441 (40%), Gaps = 81/1441 (5%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +LEG  P F+ K +     E  +++L C  V+     + W     EI P +N+ +  +  
Sbjct: 3376 VLEG-EPYFTTKLQDYTAVEKDEVVLMCE-VSKSSAQVKWFKDTNEITPSKNVLIKADGK 3433

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                  +L +   +K   G Y     + +  A L I       E+   ++  PL S+ V 
Sbjct: 3434 KR----ILTVKKAEKGNIGEYVCDCGSDKTAAKLNI-------EERDIKISRPLYSVEVT 3482

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYT 804
            + E+     ++         W      +   P    K +G  H + IL   ++   G   
Sbjct: 3483 ETETARFETEI-SEEDVHGHWKLKGDALHQSPDCEIKEEGTKHML-ILYNVRMDMAGAVD 3540

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A N    A+++A + V+  T     P       +++TV    T      ++   +P +
Sbjct: 3541 FSAAN----AKSTAQLRVKARTIGLLRP------LRDVTVTAGETATFDCELSYEDIP-V 3589

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W+  +  + PS+ +    +G    L + +V    ++G+ K  A +   +    A++T++
Sbjct: 3590 EWFVGSTKMEPSDRVVTRAEGRLHSLTLRDVIMT-EAGEVKLTAKDFVTQ----AKLTVN 3644

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983
               V F K L+     EE  T ILEC+ S      KW+ + +EI      E++ EGR   
Sbjct: 3645 EPPVEFSKPLEDQ-TVEEEATAILECELSREKADVKWFRDGQEIRKTKKHEMVAEGRIRR 3703

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                     D     C  K+ +TS  L V+    EF + L D EVKEK+ A  E E++ E
Sbjct: 3704 LIIKDCSLDDSKTYTCDAKEFKTSAFLNVEPPFVEFSKPLHDVEVKEKESAKFECEVSRE 3763

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
            +A V W +DG  I+ K  KY+   +G  R L I      DE EY C  R    +  +TVV
Sbjct: 3764 SAKVRWFKDGAEIR-KGKKYEIIAKGLQRILIISKAVFDDEAEYECDARTSKSSGMLTVV 3822

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            E        L N +  + +      E++K  A V W K   EI      +   DGKK+ L
Sbjct: 3823 EEEARFTKNLANVEGTETDSIKMVCEVSKPSAEVTWHKGDQEIPEGGRYEHVADGKKRIL 3882

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
             I D  +DDAGEY C++  S+ T  L + E +  F  R P+         A     +  +
Sbjct: 3883 IIQDLRMDDAGEYHCKLPASETTGTLKISELAAEFIAR-PQNQETVEGEKAEFVCSVSKD 3941

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
              +V W+K    +   +K+ ++ D K+R LII+ C   D+  +T  +   K++  L V  
Sbjct: 3942 NYEVKWFKGDKELTTDDKYEIVVDGKRRALIIKNCELKDEGAFTANIGSVKASANLLV-- 3999

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            +E   +I+   ++ ++K G ++ L  +  +      +W+ N++ + +      +      
Sbjct: 4000 IE-KLRIITPLKDTQVKEGQEIVLNCEVNS-EGAKAKWLKNNETMFESSKFVMAQRDTVF 4057

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
            SL IK  E +D   Y + L N  G  A    N+++ ++     +P    EI+     I +
Sbjct: 4058 SLRIKAAEKSDEASYTITLTNQRGEQAKCSANISVHEEALKIIEPLEDCEIEEKK-TITF 4116

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
                N  N T+  ++   QEI  ++ I  + + K + ++  +K  S      Y V    +
Sbjct: 4117 TCKVNRPNVTV-QWMKAGQEITLSKRILYR-VDKDKHTL-TIKDCSLADEGEYTV----V 4169

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
            +   + T    +I E           L++ T    ED E TC      +  V WYR+G++
Sbjct: 4170 AGTDKATAEL-IISEAPADFAA---QLRDQTITEFEDAEFTCKLSK-EKAHVKWYRNGRE 4224

Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
            ++     +  R                +C       +  +   + +++ PV  I      
Sbjct: 4225 IREGPRYHLERDGKECKLVVKECRPDDECEYACGVEDKRSRARLFVEEIPV-EIVRPPTD 4283

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                 G + +  A +      EV W +N   +    +Y + ++ K   +++ E++     
Sbjct: 4284 VFEPPGSDIVFEAELNK-DRVEVKWMRNNMIIVQGDKYQMISEGKVHRLQVCEIRPRDQG 4342

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
            +Y I A      + +E+      K +      ++ +  +  V      P D       ++
Sbjct: 4343 EYRIVAKEKDARAKLELAAIPKIKTTDQN---LVTDAGKPFVMAV---PYDAYPRAEAEW 4396

Query: 1702 AIEKHE-PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760
              +    P  N      D   +   Y +++  ++ +  ++++ +N  G  EA  +  ++ 
Sbjct: 4397 FFDDISLPGQN-----IDTSNERTEYRLKEPKKSDQGRYKIVIKNKHGTGEAFINLDVI- 4450

Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXX 1819
                DVP            D E V + W   E +GGS I+ Y VE +   +K W      
Sbjct: 4451 ----DVPGPVKNLHVVDTADGE-VSLAWEEPESDGGSKILAYVVERRDVKRKTWTMATDR 4505

Query: 1820 XXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   +  L  +  Y FR+ ARN +G     T+D+ +        P  P+ F+V    
Sbjct: 4506 ADIPEYCVGGLHRDNMYFFRVCARNRVGNGETVTTDEAVQAKNKFDVPDAPQKFMVGVVN 4565

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
                T+ W  P  +GGS +T+YIIE +      W   + V        + ++ E  E IF
Sbjct: 4566 RFGATVSWEPPLFDGGSEVTSYIIELRDRTSVKWEPAMVVKAEDLTATLSDVVENKEYIF 4625

Query: 1939 RISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
            R+ AEN  G+  P+  +  V++      PSPP           + V  SW TP  +GG+ 
Sbjct: 4626 RVRAENKAGIGQPSAATDPVKIMDPIERPSPP-LNFNYTNQTRDSVQLSWETPISNGGSM 4684

Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            + GY I   +     W+         L + +  L     Y  R+ A N  G+SEP ++  
Sbjct: 4685 ITGYIIEKCEDGTDKWLRCNARLCPDLYYRVSGLKFGQKYHYRVCAENAAGVSEPADAIG 4744

Query: 2058 P 2058
            P
Sbjct: 4745 P 4745



 Score =  281 bits (688), Expect = 2e-73
 Identities = 213/770 (27%), Positives = 335/770 (43%), Gaps = 42/770 (5%)

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSIN 1398
            S S S+ IK       G+Y +  +N+ G     + V +LD P P G P   E + S S  
Sbjct: 7813 SISCSMVIKDCTRAQRGVYTITAKNDGGEVKKSVIVEVLDVPGPVGVPFTAENLTSESCK 7872

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVN 1457
            + W  P++ G S I  Y++E +E +   W S       Q ++  NL    +Y FR  AVN
Sbjct: 7873 LNWFFPDDDGGSAISNYIIEKREAERKAWTSCSYTAGRQNAVVNNLVLKKAYFFRVAAVN 7932

Query: 1458 EVDISDASETTEYYKVIKET--------KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             + +   ++ T    VIK+         +++   + K   ++T +P ++   + +   + 
Sbjct: 7933 AIGVGPFNQ-TACEIVIKDRINVPDRPEELEVTAITKDHISLTWKPPKNDGGSEVISYIL 7991

Query: 1510 QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------- 1562
            + + T  +D     T     E R               ++  A N+ G  + S       
Sbjct: 7992 EAR-TIGKDKFVRLTKDKLMERRYTYDGLREGETYE--FRVSAVNEVGPGKPSFSTKPIT 8048

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
            C   ++  P I +   D K   +VG+ + +     G P P + W ++  +L+ D      
Sbjct: 8049 CKDELEP-PTIELDFRD-KVVVRVGESFALQGRYTGKPAPSITWSRDDKELKADNHIKFK 8106

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
                T  + I + +R HS KY +   N  G       + V D+P  PEGPV+  E+ R+ 
Sbjct: 8107 NTLTTMCLGIVKAQRGHSGKYCVTVENCTGARKGICNVIVADRPLPPEGPVVFDEVHRDH 8166

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRV 1741
            + I WKPPLDDGG E++ Y IEK + + + W  V       +T+C + KL E  EY+ R+
Sbjct: 8167 MVISWKPPLDDGGSEISNYIIEKRDVNRDMWTTVTSA--TTKTHCKVPKLVEGREYILRI 8224

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
             A+N  G S+ LESE +  K    VP           + N+S  + W    ++GG PI +
Sbjct: 8225 SAENMYGISDPLESEEMKAKDLFRVPE-APEQPTVKDVYNDSALVIW-NRPRDGGKPITN 8282

Query: 1802 YKVEIKQ-EGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
            Y +E K+   K+W          A   R+Q+L     Y+FR+ A NEIGT  P      I
Sbjct: 8283 YILEKKEPSAKRWSRATRDPIYPATQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPI 8342

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
                 +  PS P      + T  SV+L W  P  +G   I  Y+IE++      W K   
Sbjct: 8343 LAKDPIVLPSPPVLPEAVDKTKDSVSLSWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANE 8402

Query: 1918 VGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLE 1974
               S  +    + N+ E +E  FRI A N  G S P    + V++      P PP   L 
Sbjct: 8403 TPESCPDTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDKPGPP-RNLA 8461

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
            I  + S     +W  PE DGGA +  Y +  +DV    W+ V       L    + L E 
Sbjct: 8462 ISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAAS-KKLSLMAQYLMEG 8520

Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVI-----PGEGSHADEEPGEQTEV 2079
              Y+ R+ A N+ G S  +E+++P K +     PG   +      ++TEV
Sbjct: 8521 TQYLFRVAAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDADKTEV 8570



 Score =  246 bits (602), Expect = 5e-63
 Identities = 172/617 (27%), Positives = 272/617 (44%), Gaps = 25/617 (4%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            LDKP PP    I EI S S  + W +PE+ G + I +Y+V+ +++    W+ V   +K  
Sbjct: 8451 LDKPGPPRNLAISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAASKKL 8510

Query: 1438 TSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
            + + Q L   + Y FR  A N+   S   ET +  K +    +  P   K L ++  +  
Sbjct: 8511 SLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAVDP--LYPPGPPKNLHHVDADKT 8568

Query: 1497 E---DIELTCIFGGVPQPKVTWY--RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
            E     E     GG    ++T +     ++  T   T++                 Y+  
Sbjct: 8569 EVWLQWEWPDRTGG---SEITGFIVEHQEEGATDWVTFKTVSNPQCHVTGLVEGKTYRFR 8625

Query: 1552 AFNDHG----EVETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPE 1603
              + +       +TS  +  Q+K +      D+K       K G   L+ AV+ GIP P 
Sbjct: 8626 VKSQNAIGISRPDTSVPITCQEKTLAPTIEVDVKLIEGLVVKAGSTILLPAVMLGIPTPT 8685

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
              W   GN+L+ + ++ I T+  ++ + I E  R+ S +Y++  SN AG+ SV + + V 
Sbjct: 8686 AKWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSNPAGSKSVALHVTVL 8745

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN--NRWIKVADVDR 1721
            D PS P GPV + E++ + + I+W+ P DDGG  L  Y +EK +       W  V+    
Sbjct: 8746 DVPSAPVGPVNILEVTPDHMIIQWRAPKDDGGSPLMSYVVEKKDVKKPWEPWSVVSSGST 8805

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
              +   + +L +  EY+ RV A+N +G    LES P + K   D P            +N
Sbjct: 8806 STKAK-VPRLEKGREYIVRVRAENKIGIGAGLESPPTIAKQMFDPPGPPGQPTCSDITEN 8864

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRI 1839
             +V ++W   E +GGSP+  Y VE ++   KW           R +   +    +Y+FRI
Sbjct: 8865 -AVTVSWAEPETDGGSPVSGYIVERREMTGKWIRVNKTPVLDIRYRVCGLFEGNSYEFRI 8923

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
            +A N  G S P    D +   + +TPP  P N  + + +     L WT+P  +GGSPI  
Sbjct: 8924 FAENVAGVSQPSYPSDPMKAKRPITPPGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILG 8983

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
            Y++E +      W KI           +  + E  E  FRI A N VG   P E     L
Sbjct: 8984 YVVEIQRSGSAQWDKINKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTETVL 9043

Query: 1960 EKHATVPSPPTAPLEIR 1976
             K   VP   T  +  R
Sbjct: 9044 AKDILVPPEVTVDVACR 9060



 Score =  237 bits (580), Expect = 2e-60
 Identities = 185/723 (25%), Positives = 316/723 (43%), Gaps = 48/723 (6%)

Query: 1364 NNCGHAD---VEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVV 1417
            N CG  +   ++  V +    + P  P +L   +  + SI + W+ P   G + +  Y+V
Sbjct: 4927 NKCGPGEPAYIDEPVNVSSPATVPDPPELLKWRDKSAKSIFLLWEPPRYDGGAAVKGYIV 4986

Query: 1418 EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +  +  T +W +  + I + +  +  L     Y +R  AVN +  S   + T+  +++  
Sbjct: 4987 DKCQRGTDKWEACGDPIPELKFQVTGLIEGQWYAYRVRAVNRLGASRPCKATD--EILAV 5044

Query: 1477 TKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TY 1529
               + P ++   K L  +T      I+L     G P+P+V W +    LK  +     T 
Sbjct: 5045 DPKEPPEIQLDAKLLAGLTARAGTKIDLPADVLGKPEPRVKWTKADLVLKPEERITIDTK 5104

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-------VITISNEDI-- 1580
                              Y   A N  G    +  V I  KP       +  I+NE    
Sbjct: 5105 PGHSTLSIANTTRSDTATYIIEAVNTSGRATATVDVNILDKPGPPAAFDISEITNESCCL 5164

Query: 1581 --KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
                    G   +   ++E  P  +  W K    ++       T  + T ++ +KE    
Sbjct: 5165 AWNAPRDDGGSPVANYIVEMRPTDKEEWQKLSATIKQ------TAFKATKLVPLKE---- 5214

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV---YDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
            +  + + E     GT +  V +     +D P  P   V   +I+R++VT+ W  P +DGG
Sbjct: 5215 YVFRVSAENQYGIGTPAEHVPIVAKYSFDTPGAPTR-VQPSDITRDAVTLTWYEPDEDGG 5273

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754
              +T Y +E+ +P+ ++WIK   +     T+ ++ L    +Y FRV+A+N  G  + ++E
Sbjct: 5274 SPITGYWVERFDPETDKWIKSNKLPIKDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVE 5333

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW 1813
            ++P++IK  +D P           I   S  + W   E +GG+ I  Y +E+++ G ++W
Sbjct: 5334 TDPVLIKDPID-PPWAPGKPFVKDIAKTSADLQWTRPEHDGGAKIESYIIELQKTGTEEW 5392

Query: 1814 -KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
             +           ++ L     Y FR+ A N  G S P    D +   + L  P+ PR  
Sbjct: 5393 VRVAEDVPTTEHSLKGLMEKQEYSFRVKAINVAGESEPSDPSDPVVCKERLYVPNPPRWL 5452

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE 1932
             V   T  +  LKWTEP+S+GGSPITNY++E + V+ ++W  + T      ++ +  + E
Sbjct: 5453 EVVNITKINCDLKWTEPDSDGGSPITNYVVEKRDVRRRTWQAVDTTVKDT-KYTVTPLSE 5511

Query: 1933 KDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
                +FR++AEN VG+S   E +   L K   T P PP A L +  V    V   W  P 
Sbjct: 5512 GSLYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYA-LTVVEVSKRHVDLKWEPPN 5570

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             DGG P+  Y I  ++   T W++ GK      K+ + D+ E      ++ A NE G+  
Sbjct: 5571 SDGGRPITKYVIEKKEKVGTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGH 5630

Query: 2052 PLE 2054
            P E
Sbjct: 5631 PSE 5633



 Score =  230 bits (562), Expect = 4e-58
 Identities = 196/794 (24%), Positives = 344/794 (43%), Gaps = 52/794 (6%)

Query: 1229  WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVV 1284
             W + ++ +  + +  +        LII+  +  D  EY+ V  ++    + T K+ +  +
Sbjct: 10026 WKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDI 10085

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN--SKIIKKCKHTK----PSI 1338
               PP     E  + I   SD+       ++ +P ++   N  + +++KC  ++     ++
Sbjct: 10086 PGPP-----EPPFEI---SDIDSDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWVTAL 10137

Query: 1339  DS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-P-SPPGKP---NILEI 1392
              S   A   I K+      I+++R EN  G +D   +  ++ K P   PG+P    I ++
Sbjct: 10138 SSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDPLASERMVAKFPFDVPGEPLNCRINKV 10197

Query: 1393  DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450
             +   + + WD+PE+ G S +  Y +E +E ++  W+   +  +  T+     L     Y 
Sbjct: 10198 NKDCMFVAWDKPESDGGSPVTGYYIERKERNSLLWVKANDSVVRTTEYPCAGLIEGLEYT 10257

Query: 1451  FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KN----ITTEPNEDIELTC 1503
             FR  A+N       S+ T++  +   T + +P   + L   KN    + T+P  D     
Sbjct: 10258 FRVSAINRAGQGKPSKKTDF--ITARTPVDAPGKPEVLDVTKNAVSLVWTKPKNDGGSKI 10315

Query: 1504  I---FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
             I      +  P  TW R     +                           +  +   E+ 
Sbjct: 10316 IGYYVEAMRLPGDTWVRCNTSSQNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEIT 10375

Query: 1561  TSCVVGIQQKPV-ITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
                +V  +  P  I +S +  K    K G +  + A + G P P+V W KNG  L+ DKE
Sbjct: 10376 DPILVSAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKE 10435

Query: 1619  YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
             + ++ K     + +  + + H+  Y I A+N +G ++ E+ LK+ D P  P   V + EI
Sbjct: 10436 FKMSQKRHLFSLSLDAVTKLHAGNYGIHAANASGNTTAEIQLKILDIPG-PPASVKLDEI 10494

Query: 1679  SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEY 1737
               + V + W+ PL DGG  +T Y ++K E     W +V A + RD     +++L E  EY
Sbjct: 10495 LSDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEY 10554

Query: 1738  MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
              FRV A+N  G  +A+ SEP+V +    VP           I  E + ++W     +G S
Sbjct: 10555 QFRVRAENHYGTGDAIISEPVVARNPFTVPG-ACDPPVLTNITKEHMTVSWKEPSDDGKS 10613

Query: 1798  PIIDYKVEIKQEGKK--WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
             PI+ Y VE K+E K+  W              +  LS    Y+FR+ A N+ G   P   
Sbjct: 10614 PILGYLVE-KRETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFRVIAVNKAGLGKPSDP 10672

Query: 1854  DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
              +  +    L PP  P +    ++T+ ++ L WT+P ++GGS I  Y++E K +    W 
Sbjct: 10673 SNAASALDPLYPPGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVECKRINTTDWI 10732

Query: 1914  KI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
             +  V        + +  + E  E   R+SA N +G S P E     + K   V   P A 
Sbjct: 10733 RCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPEKHIAKDVFV--TPEAE 10790

Query: 1973  LEIRMVGSNIVMTS 1986
             L+  +    +V+T+
Sbjct: 10791 LDAEL-KDTLVLTA 10803



 Score =  222 bits (542), Expect = 1e-55
 Identities = 196/832 (23%), Positives = 345/832 (41%), Gaps = 42/832 (5%)

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP-PKIVDYEREYRIKRGSDVTLL 1308
            +++I+ CT   +  YT    +     K  V  EV++ P P  V +  E        +   
Sbjct: 7817 SMVIKDCTRAQRGVYTITAKNDGGEVKKSVIVEVLDVPGPVGVPFTAENLTSESCKLNWF 7876

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                        +I+  +  ++   T  S  +   +  +  +    A  +++   N  G 
Sbjct: 7877 FPDDDGGSAISNYIIEKREAERKAWTSCSYTAGRQNAVVNNLVLKKAYFFRVAAVNAIGV 7936

Query: 1369 ADVEMN---VTILDKPSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEI 1422
                     + I D+ + P +P  LE+ + +   I++ W  P+N G S +I Y++E + I
Sbjct: 7937 GPFNQTACEIVIKDRINVPDRPEELEVTAITKDHISLTWKPPKNDGGSEVISYILEARTI 7996

Query: 1423 DTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
               +++ +    + + + +   L+   +Y FR  AVNEV     S +T+   +  + +++
Sbjct: 7997 GKDKFVRLTKDKLMERRYTYDGLREGETYEFRVSAVNEVGPGKPSFSTK--PITCKDELE 8054

Query: 1481 SPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXX--- 1535
             PT+E   ++ +     E   L   + G P P +TW RD K+LK      ++N       
Sbjct: 8055 PPTIELDFRDKVVVRVGESFALQGRYTGKPAPSITWSRDDKELKADNHIKFKNTLTTMCL 8114

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI---TISNEDIKQKHKVGDEWLV 1592
                        Y     N  G  +  C V +  +P+     +  +++ + H V   W  
Sbjct: 8115 GIVKAQRGHSGKYCVTVENCTGARKGICNVIVADRPLPPEGPVVFDEVHRDHMV-ISWKP 8173

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                 G      I  K    +  D    +T+    +  ++ +L         I A N  G
Sbjct: 8174 PLDDGGSEISNYIIEK--RDVNRDMWTTVTSATTKTHCKVPKLVEGREYILRISAENMYG 8231

Query: 1653 TS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
             S    S E+  K ++  P  PE P + +++  +S  + W  P  DGG  +T Y +EK E
Sbjct: 8232 ISDPLESEEMKAKDLFRVPEAPEQPTV-KDVYNDSALVIWNRP-RDGGKPITNYILEKKE 8289

Query: 1708 PDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALD 1765
            P   RW +   D       Y +Q+L E CEY FRV A+N +G  + ++ S+PI+ K  + 
Sbjct: 8290 PSAKRWSRATRDPIYPATQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDPIV 8349

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW----KXXXXXX 1820
            +PS             +SV ++W     +G   I  Y +E ++ G  +W    +      
Sbjct: 8350 LPSPPVLPEAVDK-TKDSVSLSWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANETPESCP 8408

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                 +  L     +QFRI A N  G S P    + + +   L  P  PRN  +SE TS 
Sbjct: 8409 DTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDKPGPPRNLAISEITSE 8468

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
            S  L W +PE +GG+ I++YI++ K V  ++W  +      +     + + E  + +FR+
Sbjct: 8469 SAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAASKKL-SLMAQYLMEGTQYLFRV 8527

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            +AEN  G S   E+           P  P   L         V   W  P+  GG+ + G
Sbjct: 8528 AAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDADKTEVWLQWEWPDRTGGSEITG 8587

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            + +  ++   T W  V    V+  + ++  L E  TY  R+ ++N IG+S P
Sbjct: 8588 FIVEHQEEGATDW--VTFKTVSNPQCHVTGLVEGKTYRFRVKSQNAIGISRP 8637



 Score =  218 bits (532), Expect = 2e-54
 Identities = 140/457 (30%), Positives = 218/457 (47%), Gaps = 16/457 (3%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPE---GPVIMREISR 1680
            K +  R+K L      K+ + A N AG    SVE    +   P  P    G   +++I++
Sbjct: 5300 KDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVETDPVLIKDPIDPPWAPGKPFVKDIAK 5359

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
             S  ++W  P  DGG ++  Y IE  +     W++VA+ D     + ++ L E  EY FR
Sbjct: 5360 TSADLQWTRPEHDGGAKIESYIIELQKTGTEEWVRVAE-DVPTTEHSLKGLMEKQEYSFR 5418

Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            V A N  G SE  + S+P+V K  L VP+          I   +  + W   + +GGSPI
Sbjct: 5419 VKAINVAGESEPSDPSDPVVCKERLYVPNPPRWLEVVN-ITKINCDLKWTEPDSDGGSPI 5477

Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
             +Y VE +   ++ W+            +  LS  + Y FR+ A N +G S     +D +
Sbjct: 5478 TNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSV 5537

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
                T T P  P    V E + R V LKW  P S+GG PIT Y+IE K   G  W K   
Sbjct: 5538 LAKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKSGK 5597

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
              G   ++ + ++ E  E+ F++ AEN  GV  P+E   +   + A   SPP+ PLE+++
Sbjct: 5598 TSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAI--SPPSPPLEVKI 5655

Query: 1978 VGSN--IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD-LSEN 2034
            V ++   +  +W  PE +GG+P+ GY++ + +     WM +    V  L+F   + +   
Sbjct: 5656 VDASREHINITWKAPEKNGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPE 5715

Query: 2035 HTYMIRIYARNEIGLSEPLE-SDEPFKVIPGEGSHAD 2070
              Y++R+ A N IG+S+P E SD  F   P      D
Sbjct: 5716 KKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTID 5752



 Score =  210 bits (513), Expect = 3e-52
 Identities = 172/690 (24%), Positives = 281/690 (40%), Gaps = 40/690 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            I+ G  + L       P P  +W  +     K +H     + KS++L+IKK   TD GIY
Sbjct: 6483 IRAGETLRLPAVVTGRPVPEVKWTKDGAEPDK-EHVVIEAEIKSSTLSIKKALRTDHGIY 6541

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
            ++   N  G   V + V ++D P P      + +    I++ W +P + G S I+ YVVE
Sbjct: 6542 QITGTNPSGTKSVSVKVDVMDVPGPVVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVE 6601

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             ++     +     +   +  I  L     Y FR  A N+  +    E      V  +  
Sbjct: 6602 RKDAKMHIYRQPLEVAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDPKGV 6661

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-----RDGKKLKTAKATYENRX 1533
              +P   +  +          E     GG   P + +Y     +D  +   A        
Sbjct: 6662 PSAPEKLRYTERTKNTITLTWEAPRSDGG--SPIIGYYIEKMRQDSNEYDVANRNLCKDL 6719

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVIT----ISNEDIKQKH 1584
                          ++  A N+ G  E S  + +     +  P +       ++ I  + 
Sbjct: 6720 TITLENLTENMMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRK 6779

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK------TSVIRIKELKRS 1638
                E  + A I G+P P   W KNG  ++   E      E+      T+ I I E  R 
Sbjct: 6780 GAAIE--IPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQ 6837

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
             +  Y + A+NT G     + + + D+P  P   +++ +I  ES  + W  P D+GG +L
Sbjct: 6838 DTGMYKLTATNTRGVGQRTMRVDILDRPLPPRN-IVVSDIKAESCYLTWDAPEDNGGSDL 6896

Query: 1699 TKYAIEKHEPDNNR--WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
            T Y +EK +    +  W ++     D   Y + KL     Y F++ A+N  G S+  ESE
Sbjct: 6897 TNYIVEKRDASKKKSDWDQLTCCIMD-RRYGVYKLEAYGTYQFQIKAENKYGISDGCESE 6955

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKX 1815
             +V+K    +P               S+ +TW P + NGGS I  Y +E ++ G   W  
Sbjct: 6956 KVVLKDPFGLPGPPQRPRIISHT-RSSMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSR 7014

Query: 1816 XXXXXXXXARIQKLSINTT-------YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
                      ++ L  N         Y+FR+ A+N  G   P  + + +       PPSQ
Sbjct: 7015 VNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATECVFALDPRNPPSQ 7074

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHC 1926
            P   VV++ +  SV+L WT P+ +GGSPI  YI+E +      W +I T    +  + + 
Sbjct: 7075 PPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYT 7134

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            +  +KE  +  FRI A N  G S P+   S
Sbjct: 7135 VPGLKENKKCRFRIVAVNAAGESEPSPRTS 7164



 Score =  208 bits (508), Expect = 1e-51
 Identities = 139/483 (28%), Positives = 222/483 (45%), Gaps = 19/483 (3%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSK 1642
            K GD   + A + G P PEV W K G+  +  K   +  +  T+   +++   +R  + K
Sbjct: 9359 KAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGK 9418

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y I A+N AGT S E  + V D+P  P   + + +IS +   + W+ P DDGG E+  Y 
Sbjct: 9419 YIITATNAAGTCSAEAKVNVLDRPG-PIRDLKVSDISIDRCKLAWEIPEDDGGCEIYNYI 9477

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            IEK E     W  +        +  + +L E  EY+FRV A+N +G   A+ESE I+ +T
Sbjct: 9478 IEKCEAKRGVW-SIHSAAIITNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESIIART 9536

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821
                P           I  +++ + W   + +GG PI  Y +E K+E   +W        
Sbjct: 9537 QFSRPGAPDAPEVTK-ITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVKSPY 9595

Query: 1822 XXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
               ++   S+  N  YQFR+ A NEIG           T    + PP    N  V++S+ 
Sbjct: 9596 AGTQMTVTSLLPNHEYQFRVKAENEIGVGDASKPSRTFTARDPVEPPGPVSNLKVTDSSK 9655

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSV--HEHCIENIKEK 1933
             S+TL WT+P  +GG+P+  Y++E +      KG    K   V   +   E  + ++ EK
Sbjct: 9656 TSITLAWTKPTYDGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEK 9715

Query: 1934 DEIIFRISAENT----VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
             E  FR++ +++    + VS P   ++V +         P   LE+  +  +    +W  
Sbjct: 9716 LEYEFRVTRDDSGKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTDMTMSSCNLTWSP 9775

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            PE DGG+ +  Y +  R++ +  W  V K +V    F I +L     Y  R+ A NE G 
Sbjct: 9776 PETDGGSNVTHYIVEKREIDRKTWATV-KANVEKTTFKISNLVPGTEYYFRVVAVNEYGP 9834

Query: 2050 SEP 2052
              P
Sbjct: 9835 GVP 9837



 Score =  195 bits (475), Expect = 1e-47
 Identities = 169/698 (24%), Positives = 279/698 (39%), Gaps = 40/698 (5%)

Query: 1384  PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTS 1439
             PGKP +L++  +++++ W +P+N G S II Y VE   +    W+    S +N+ + + +
Sbjct: 10287 PGKPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSSQNVPREEYT 10346

Query: 1440  IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTEPN 1496
                L+  ++Y+FR  A   V+IS  SE T+   ++   +   P +E  +   K +  +  
Sbjct: 10347 ATGLEEGANYQFRVIAKTAVNISRPSEITD--PILVSAENVPPRIELSVQMKKMLPVKAG 10404

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552
              D+ L     G P PKVTW ++G+ LK  K    +   +                Y   A
Sbjct: 10405 SDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFSLSLDAVTKLHAGNYGIHA 10464

Query: 1553  FNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
              N  G         ++ I   P     +E +  + K+   W    V  G P    +  K 
Sbjct: 10465 ANASGNTTAEIQLKILDIPGPPASVKLDEILSDRVKL--SWEAPLVDGGSPITNYVVDKR 10522

Query: 1610  GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSK 1668
                     + +      T+   ++ L   H  ++ + A N  GT    ++  V  + P  
Sbjct: 10523 ETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYGTGDAIISEPVVARNPFT 10582

Query: 1669  PEG---PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
               G   P ++  I++E +T+ WK P DDG   +  Y +EK E     W K+        T
Sbjct: 10583 VPGACDPPVLTNITKEHMTVSWKEPSDDGKSPILGYLVEKRETKEVNWTKINRKPLLERT 10642

Query: 1726  YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNES 1783
               +  L+E  +Y FRVIA N  G  +   S+P    +ALD   P             N +
Sbjct: 10643 LEVGGLSEGAQYEFRVIAVNKAGLGK--PSDPSNAASALDPLYPPGPPISPKAIDTTNST 10700

Query: 1784  VYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW---KXXXXXXXXXARIQKLSINTTYQFRI 1839
             + +TW     +GGS I+ Y VE K+     W               +  L  N+ YQ R+
Sbjct: 10701 IKLTWTKPANDGGSDILGYLVECKRINTTDWIRCNVPKNLQDTNYVVTGLLENSEYQLRV 10760

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
              A N+IG S P    +K         P    +  + ++   +   K        G PI  
Sbjct: 10761 SAVNKIGFSQPCEVPEKHIAKDVFVTPEAELDAELKDTLVLTAGSKMKLHAKIKGRPIPR 10820

Query: 1900  YI-IEFKT-VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
                 +  T +K +    I T        C+E +   D   + ++ ++  G+ + T     
Sbjct: 10821 VTWAKMNTNIKDRQGIIIKTTDTDTLV-CVEKVNRYDAGKYILNLDSVSGMKMYTV---- 10875

Query: 1958  RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
              + K    P PP   L I+    +     W  P  DGG+ + GY +  RD  +  W  V 
Sbjct: 10876 -IVKVLDTPGPP-LNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVT 10933

Query: 2018  KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
                  T  F I DL    +Y  R+ A+N+ G+ EP E+
Sbjct: 10934 TSCTKT-SFKIEDLEPGRSYCFRVLAQNQYGIGEPCET 10970



 Score =  188 bits (458), Expect = 1e-45
 Identities = 198/885 (22%), Positives = 344/885 (38%), Gaps = 51/885 (5%)

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
            Y+K   IE  +             ++    E ++ ++  + ++A    K +   V+ P K
Sbjct: 8389 YQKPGAIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMAVNAAG--KSEPAYVKEPVK 8446

Query: 1290 IVDYEREYRIKRG---SDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSID 1339
            + D   +    R    S++T    Y  + +P D+       +IV  K +           
Sbjct: 8447 VHDRLDKPGPPRNLAISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAA 8506

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTI--LDKPSPPGKPNIL---EID 1393
            SK  SL  + +      ++++  EN  G  A VE N  I  +D   PPG P  L   + D
Sbjct: 8507 SKKLSLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDAD 8566

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
             + + + W+ P+ TG S I  ++VE+QE   T+W++ K ++  Q  +  L    +YRFR 
Sbjct: 8567 KTEVWLQWEWPDRTGGSEITGFIVEHQEEGATDWVTFKTVSNPQCHVTGLVEGKTYRFRV 8626

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQ 1510
             + N + IS    +     +  + K  +PT+E   K ++ +  +    I L  +  G+P 
Sbjct: 8627 KSQNAIGISRPDTSV---PITCQEKTLAPTIEVDVKLIEGLVVKAGSTILLPAVMLGIPT 8683

Query: 1511 PKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---C 1563
            P   W  +G +LKT       T  N                Y     N  G    +    
Sbjct: 8684 PTAKWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSNPAGSKSVALHVT 8743

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
            V+ +   PV  ++  ++   H +  +W       G P    +  K   K   +    +++
Sbjct: 8744 VLDVPSAPVGPVNILEVTPDHMI-IQWRAPKDDGGSPLMSYVVEKKDVKKPWEPWSVVSS 8802

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNT----AGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
               ++  ++  L++       + A N     AG  S     K    P  P G     +I+
Sbjct: 8803 GSTSTKAKVPRLEKGREYIVRVRAENKIGIGAGLESPPTIAKQMFDPPGPPGQPTCSDIT 8862

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
              +VT+ W  P  DGG  ++ Y +E+ E    +WI+V         Y +  L E   Y F
Sbjct: 8863 ENAVTVSWAEPETDGGSPVSGYIVERREM-TGKWIRVNKTPVLDIRYRVCGLFEGNSYEF 8921

Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            R+ A+N  G S+ +  S+P+  K  +  P                  + W    ++GGSP
Sbjct: 8922 RIFAENVAGVSQPSYPSDPMKAKRPI-TPPGPPSNIKLKDWSKSYADLVWTKPSRDGGSP 8980

Query: 1799 IIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            I+ Y VEI++ G  +W             R+  L+    Y+FRI A N++G   P    +
Sbjct: 8981 ILGYVVEIQRSGSAQWDKINKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTE 9040

Query: 1856 KITIGKTLTPPSQPRNFVVSE-STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
             +     L PP    +    +  T R+  +        G         +   V G+    
Sbjct: 9041 TVLAKDILVPPEVTVDVACRDLLTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRT 9100

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
             +     + E  I++    D   + I A+N+ G     ++Q+  +     +P      L+
Sbjct: 9101 EMNNNFPLVELVIQDAVRADYGKYAIQAKNSSG-----QAQATIIVNVLDIPG-ACQNLK 9154

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
            +  V  +  M SW  PE +GG  +  Y I  R  ++  W  V   D  T +     L +N
Sbjct: 9155 VAYVTKDSCMVSWENPEDNGGTEITNYKIECRQPSQRGWTVVSS-DC-TKRLVKAPLVQN 9212

Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
              Y  R+ A N+IG   P ES  P   +       + E  + TE+
Sbjct: 9213 CEYFFRVSAENKIGAGPPTESKTPVLAVDPVEKPGEPENFQITEI 9257



 Score =  186 bits (452), Expect = 8e-45
 Identities = 181/713 (25%), Positives = 289/713 (40%), Gaps = 50/713 (7%)

Query: 1376 TILDKPSPPG---KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
            T+L +  PPG   KP I  +   S+ + W+EPE+ G S I  Y +E +E  +  W  V  
Sbjct: 7547 TLLIQQVPPGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLERKETTSKRWSRVTR 7606

Query: 1433 --ITKTQTSIQNLKTN----SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
              +      + +  T     S Y FR  A+N   +   SE +E         I  P+   
Sbjct: 7607 DPVRPMPMGVSHRVTGLIEGSQYLFRVSAINAAGVGPPSEPSE--PTFAREPIAPPSPPT 7664

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXXXXXXXXX 1541
            P     T+   D+E            + ++ + K+  T     AK               
Sbjct: 7665 PKVTDWTKTTADLEWIPPLKDGGSKIIGYFVEYKEEGTEAWVKAKDKEVRGTKFVITGLK 7724

Query: 1542 XXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTA 1594
                  ++ IA N  G     E +  + ++ + ++ +   D+  K K+    G    + A
Sbjct: 7725 ENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKMVIHAGGVIRILA 7784

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             + G PPP + W ++   + ++     TT    S++ IK+  R+    YTI A N  G  
Sbjct: 7785 YVSGQPPPVITWSRDEYPVPSEAVIE-TTSISCSMV-IKDCTRAQRGVYTITAKNDGGEV 7842

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
               V ++V D P     P     ++ ES  + W  P DDGG  ++ Y IEK E +   W 
Sbjct: 7843 KKSVIVEVLDVPGPVGVPFTAENLTSESCKLNWFFPDDDGGSAISNYIIEKREAERKAWT 7902

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXX 1773
                     +   +  L     Y FRV A N +G     ++   IVIK  ++VP      
Sbjct: 7903 S-CSYTAGRQNAVVNNLVLKKAYFFRVAAVNAIGVGPFNQTACEIVIKDRINVPD-RPEE 7960

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLS 1830
                 I  + + +TW P + +GGS +I Y +E +  GK K+           R     L 
Sbjct: 7961 LEVTAITKDHISLTWKPPKNDGGSEVISYILEARTIGKDKFVRLTKDKLMERRYTYDGLR 8020

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF----VVSESTSRSVTLKW 1886
               TY+FR+ A NE+G   P  S   IT    L PP+   +F    VV    S ++  ++
Sbjct: 8021 EGETYEFRVSAVNEVGPGKPSFSTKPITCKDELEPPTIELDFRDKVVVRVGESFALQGRY 8080

Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK--DEIIFRISAEN 1944
            T       +P   +  + K +K  +  K      ++   C+  +K +      + ++ EN
Sbjct: 8081 T----GKPAPSITWSRDDKELKADNHIKF---KNTLTTMCLGIVKAQRGHSGKYCVTVEN 8133

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
              G      +  V     A  P PP  P+    V  + ++ SW  P  DGG+ +  Y I 
Sbjct: 8134 CTGARKGICNVIV-----ADRPLPPEGPVVFDEVHRDHMVISWKPPLDDGGSEISNYIIE 8188

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             RDV + MW  V      T    +  L E   Y++RI A N  G+S+PLES+E
Sbjct: 8189 KRDVNRDMWTTVTSATTKT-HCKVPKLVEGREYILRISAENMYGISDPLESEE 8240



 Score =  184 bits (448), Expect = 2e-44
 Identities = 192/758 (25%), Positives = 311/758 (41%), Gaps = 65/758 (8%)

Query: 1349 KVENTDAGI---YKLRLENNCG--H-ADVEMNVTILDKPSPPGKP---NILEIDSSSINI 1399
            +V + D G    +++R EN  G  H ++  + +TI D  SPP  P    I++     INI
Sbjct: 5606 RVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPSPPLEVKIVDASREHINI 5665

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI---QNLKTNSSYRFRAYAV 1456
             W  PE  G S I  Y VE  E +T +W+ +      +      + +     Y  R  A+
Sbjct: 5666 TWKAPEKNGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAI 5725

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N + +SD SE ++   V  +    +PT++   ++I     E +++   +  +P+P + W 
Sbjct: 5726 NAIGVSDPSEISD--GVFAKDPDSAPTIDVATQDIVVVEGEKMDIKIPYRAIPKPSMVWK 5783

Query: 1517 RDGKKLKTAKA---TYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQ 1569
            +   +LKT      T E NR               Y     N  G V  +    V+G+  
Sbjct: 5784 KGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTGTVSVTVIGLPG 5843

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTKEKTS 1628
            +      +E  K   K+   W       G P   ++ Y    +    K +  + + E   
Sbjct: 5844 QCKDISPSELTKNSCKIS--WEPPENDGGSP---ILHYVLERREAQKKTFLPVMSGENVL 5898

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSK--PEGPVIMREIS--RESV 1683
               +K+L  +    + ++A N  G+   +E+   V  +  K  P+ P+ +  ++    S+
Sbjct: 5899 SFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSI 5958

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
            T+ W  P  DGG  +T Y IEK E D +R+ +         +Y +  L E  EY FRV A
Sbjct: 5959 TVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRA 6018

Query: 1744 QNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID-------------NESVY--IT 1787
            +N  G S+   S P+++    +D P           +              + S Y  +T
Sbjct: 6019 ENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLSIKKGEEIRLDAYISGSPYPTVT 6078

Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTY--QFRIYARNE 1844
            W  +++N   P    K EI ++ KK  +           + +LS   T   +  +  R+ 
Sbjct: 6079 WLRNDENVRQPPAKKKPEIVKKKKKTVQPEPEEEFHPPLVDRLSYEQTKKGETALMVRDA 6138

Query: 1845 IGTSLP-YTSDDKITIG--------KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            I T    +T   +   G          L  P  P NF   E  + SV   W  P  +GGS
Sbjct: 6139 IRTDHGNFTIRVENAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCTWDAPLDDGGS 6198

Query: 1896 PITNYIIEFK--TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
             I NYI+E K  T     W   VT     + + +  + E  E IFR++AEN  G   P  
Sbjct: 6199 EIINYILEKKDNTSDDIGWV-TVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHPCY 6257

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
            S+ +  +     P  P  P  I  V S+ V  SW  P+ D G+P+LGY +  R+V    W
Sbjct: 6258 SEPLVAKNQFEPPDAPNVP-RIGEVTSSTVALSWHEPK-DNGSPILGYWVERREVNSKYW 6315

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            + V    ++ L   +  L E   Y+ R+ A N  G  E
Sbjct: 6316 IRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGE 6353



 Score =  178 bits (434), Expect = 1e-42
 Identities = 170/701 (24%), Positives = 288/701 (41%), Gaps = 39/701 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITK-TQT 1438
            P PP    + +   S  ++ W +P   G S I+ YVVE Q   + +W  + K++ K    
Sbjct: 8950 PGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILGYVVEIQRSGSAQWDKINKDLIKFCAF 9009

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP--TVEKPLKNI-TTEP 1495
             +  L     YRFR  A N+V   +  E TE   V+ +  +  P  TV+   +++ T   
Sbjct: 9010 RVPGLNEGIEYRFRIKASNKVGDGEPRELTE--TVLAKDILVPPEVTVDVACRDLLTVRA 9067

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXXXXXXXYKCI 1551
             + I L     G P P++TW +D + L   K T  N                    Y   
Sbjct: 9068 GQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDAVRADYGKYAIQ 9127

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKNG 1610
            A N  G+ + + +V +   P      +++K  +   D  +V+    E     E+  YK  
Sbjct: 9128 AKNSSGQAQATIIVNVLDIPGAC---QNLKVAYVTKDSCMVSWENPEDNGGTEITNYKIE 9184

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV--YD 1664
             +  + + + + + + T  +    L ++    + + A N  G    T S    L V   +
Sbjct: 9185 CRQPSQRGWTVVSSDCTKRLVKAPLVQNCEYFFRVSAENKIGAGPPTESKTPVLAVDPVE 9244

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
            KP +PE   I  EI +  V ++WK P  DGG     Y +EK   + + W ++        
Sbjct: 9245 KPGEPENFQIT-EIGKTFVFLKWKKPEYDGGSRNLAYHVEKKPKEADEWERLHKGAIKET 9303

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NES 1783
             +   +  EN  Y FRV  +N  G S  + +  +++K  L  P           +   ++
Sbjct: 9304 YFMADRCIENQIYQFRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDA 9363

Query: 1784 VYITWFPSEKNGG-SPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838
            V I    +E  G   P + +  E       +G + +          ++       T ++ 
Sbjct: 9364 VSIE---AELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYI 9420

Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            I A N  GT    +++ K+ +   L  P   R+  VS+ +     L W  PE +GG  I 
Sbjct: 9421 ITATNAAGTC---SAEAKVNV---LDRPGPIRDLKVSDISIDRCKLAWEIPEDDGGCEIY 9474

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
            NYIIE    K   W+ I +     +   +  + E +E IFR+ AEN +G     ES+S+ 
Sbjct: 9475 NYIIEKCEAKRGVWS-IHSAAIITNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESII 9533

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
                 + P  P AP E+  +  + ++  W +P+ DGG P+ GY +  ++     W  V K
Sbjct: 9534 ARTQFSRPGAPDAP-EVTKITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVK 9592

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
                  +  +  L  NH Y  R+ A NEIG+ +  +    F
Sbjct: 9593 SPYAGTQMTVTSLLPNHEYQFRVKAENEIGVGDASKPSRTF 9633



 Score =  178 bits (433), Expect = 2e-42
 Identities = 229/1033 (22%), Positives = 417/1033 (40%), Gaps = 89/1033 (8%)

Query: 660  IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            I E D+   W  +G+ +       +  E         L I NV+  Q G  T  A+N   
Sbjct: 2960 ISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRF----LTIKNVQLDQAGEVTYQALNAVT 3015

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             A    +L +K G+      ++   ++   + + V    ++  +    + W  N   +KA
Sbjct: 3016 SA----MLNVKEGDAFFSVKLQDYTAV---EKDEVTFDCELSRDV--PVKWFHNEIEIKA 3066

Query: 778  LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
                +        IL  KKV  KD+GVY        G  +TS+ + +E    +  +P   
Sbjct: 3067 SKMVTIKVEGKRRILNLKKVENKDKGVYVCDC----GTDKTSSNLNIEARDIKVVKPIYG 3122

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
            +  F      +  T +    ++ + V    W    +++S S  +    DG    L + N 
Sbjct: 3123 VELF------DGETARFEVEISEDDVHG-QWKLKGDVLSASPDVEIIEDGAKHTLTLYNC 3175

Query: 896  DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ--KSYETEEGKTVILECQTS 953
                 SG+     +N+  K S  A + +    ++FV  L   + YE +E +  I   + +
Sbjct: 3176 RVS-QSGEVTFQGANA--KCS--ANLKVKELPISFVMPLSDVQVYEKDEARFEIELSREA 3230

Query: 954  HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
             TV  +W    +E+   +  EI+ EG+            D        +D+ TS  LV++
Sbjct: 3231 KTV--RWLKGSQELKVDEKFEILAEGKRHILVVKSVAYEDEAKYMFEAEDKRTSAKLVIQ 3288

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
                EF+R ++D  VKE++ A   +E++ E   V W ++   + P K  +   + G I  
Sbjct: 3289 GIRLEFVRPIKDVTVKERETAEFSIELSHEKIQVTWYKNDVRLHPSKVVH-MSEHGKIHT 3347

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133
            L  +  S+ D          ++  A +TV+E  P   T+LQ+    + ++     E++K 
Sbjct: 3348 LSFKEVSIDDTSLIKVEALGKTSEAMLTVLEGEPYFTTKLQDYTAVEKDEVVLMCEVSKS 3407

Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
             A V+WFKD +EI  S ++ +  DGKK+ L +   +  + GEY C+ G+ K  A L +EE
Sbjct: 3408 SAQVKWFKDTNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIEE 3467

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
              I  +  L    +    T  + T EI +E +   W  K   +  +    +  +  K  L
Sbjct: 3468 RDIKISRPLYSVEVTETETARFET-EISEEDVHGHWKLKGDALHQSPDCEIKEEGTKHML 3526

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDY 1311
            I+     D          +AKST +L+V+       ++   R+  +  G   T    + Y
Sbjct: 3527 ILYNVRMDMAGAVDFSAANAKSTAQLRVKARTI--GLLRPLRDVTVTAGETATFDCELSY 3584

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
            +  P    EW V S  ++         + +  SLT++ V  T+AG  KL  ++    A  
Sbjct: 3585 EDIPV---EWFVGSTKMEPSDRVVTRAEGRLHSLTLRDVIMTEAGEVKLTAKDFVTQA-- 3639

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
               +T+ + P    KP    ++  ++     E E T    I+   +  ++ D   +   +
Sbjct: 3640 --KLTVNEPPVEFSKP----LEDQTV-----EEEAT---AILECELSREKADVKWFRDGQ 3685

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT---EYYKVIKETKIQSPTVE--K 1486
             I KT+      +  +  R R   + +  + D+   T   + +K      ++ P VE  K
Sbjct: 3686 EIRKTKKH----EMVAEGRIRRLIIKDCSLDDSKTYTCDAKEFKTSAFLNVEPPFVEFSK 3741

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546
            PL ++  +  E  +  C        KV W++DG +++  K  YE                
Sbjct: 3742 PLHDVEVKEKESAKFECEVSR-ESAKVRWFKDGAEIRKGK-KYE-----IIAKGLQRILI 3794

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI-----P 1600
              K + F+D  E E       +   ++T+  E+ +  K+    E   T  I+ +     P
Sbjct: 3795 ISKAV-FDDEAEYECDARTS-KSSGMLTVVEEEARFTKNLANVEGTETDSIKMVCEVSKP 3852

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--TIEASNTAGTSSV-E 1657
              EV W+K   ++     Y      K  ++ I++L+   + +Y   + AS T GT  + E
Sbjct: 3853 SAEVTWHKGDQEIPEGGRYEHVADGKKRILIIQDLRMDDAGEYHCKLPASETTGTLKISE 3912

Query: 1658 VTLKVYDKPSKPE 1670
            +  +   +P   E
Sbjct: 3913 LAAEFIARPQNQE 3925



 Score =  175 bits (427), Expect = 8e-42
 Identities = 115/401 (28%), Positives = 183/401 (45%), Gaps = 18/401 (4%)

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             K G +  V A++ G P P   W +  N + +     +   +   V+ IK++ R  S +Y+
Sbjct: 10005 KAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYS 10064

Query: 1645  IEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
             + A N++G   +E TLK+   D P  PE P  + +I  ++ T+ W  P +DGG  +T Y 
Sbjct: 10065 LVAENSSG--KIEQTLKIIIRDIPGPPEPPFEISDIDSDACTLSWNKPTEDGGSNITNYV 10122

Query: 1703  IEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
             +EK +     W  V  +    +  C I KL    EY+FRV A+N  G S+ L SE +V K
Sbjct: 10123 VEKCDVSRGDW--VTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDPLASERMVAK 10180

Query: 1762  TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820
                DVP           ++ + +++ W   E +GGSP+  Y +E K+     W       
Sbjct: 10181 FPFDVPG-EPLNCRINKVNKDCMFVAWDKPESDGGSPVTGYYIERKERNSLLWVKANDSV 10239

Query: 1821  XXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                       +     Y FR+ A N  G   P    D IT    +  P +P    V + T
Sbjct: 10240 VRTTEYPCAGLIEGLEYTFRVSAINRAGQGKPSKKTDFITARTPVDAPGKPE---VLDVT 10296

Query: 1879  SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHCIENIKEKDEI 1936
               +V+L WT+P+++GGS I  Y +E   + G +W +  T   +V   E+    ++E    
Sbjct: 10297 KNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSSQNVPREEYTATGLEEGANY 10356

Query: 1937  IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
              FR+ A+  V +S P+E     L     V  PP   L ++M
Sbjct: 10357 QFRVIAKTAVNISRPSEITDPILVSAENV--PPRIELSVQM 10395



 Score =  174 bits (423), Expect = 3e-41
 Identities = 168/718 (23%), Positives = 288/718 (40%), Gaps = 58/718 (8%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +  G  + + + Y+A P+P+  W      +K       + +     L + K ++ DAG+Y
Sbjct: 5760 VVEGEKMDIKIPYRAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVY 5819

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             + LEN+ G     ++VT++  P      +  E+  +S  I W+ PEN G S I++YV+E
Sbjct: 5820 TVTLENSLGSVTGTVSVTVIGLPGQCKDISPSELTKNSCKISWEPPENDGGSPILHYVLE 5879

Query: 1419 YQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +E     ++ V +     +  +++L  NS Y FR  AVN++   +  E      + ++ 
Sbjct: 5880 RREAQKKTFLPVMSGENVLSFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQK 5939

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWY------RDGKKLKTAKATYE 1530
            +   P +E    N T+       +   + GG P   +T Y      +DG + +       
Sbjct: 5940 QHPDPPIEVAGLNPTSNSITVTWMAPPYDGGCP---ITGYIIEKIEKDGDRFERCVPNLV 5996

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQ--QKPVITI-SNEDIKQK 1583
                             ++  A N  G  +    T  ++       P +T+ +       
Sbjct: 5997 PGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLS 6056

Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN---DKEYNITTKEKTSV----------- 1629
             K G+E  + A I G P P V W +N   +      K+  I  K+K +V           
Sbjct: 6057 IKKGEEIRLDAYISGSPYPTVTWLRNDENVRQPPAKKKPEIVKKKKKTVQPEPEEEFHPP 6116

Query: 1630 ----IRIKELKRSHSSKYTIEASNT-AGTSSVEV-----------TLKVYDKPSKPEGPV 1673
                +  ++ K+  ++    +A  T  G  ++ V            + V DKP  P    
Sbjct: 6117 LVDRLSYEQTKKGETALMVRDAIRTDHGNFTIRVENAHGFATASCDVNVLDKPGPPVN-F 6175

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVADVDRDVETYCIQKL 1731
               EI   SV   W  PLDDGG E+  Y +EK +   D+  W+ V    +    Y + KL
Sbjct: 6176 GFDEIRNTSVVCTWDAPLDDGGSEIINYILEKKDNTSDDIGWVTVTSTHKGY-NYPVTKL 6234

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
             E  EY+FRV A+N  G      SEP+V K   + P           + + +V ++W   
Sbjct: 6235 IEGKEYIFRVTAENKFGCGHPCYSEPLVAKNQFE-PPDAPNVPRIGEVTSSTVALSWH-E 6292

Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTS 1848
             K+ GSPI+ Y VE ++   K+          A   +++ L     Y FR+ A N  G  
Sbjct: 6293 PKDNGSPILGYWVERREVNSKYWIRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPG 6352

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
                  D       + PP  P   +V + T+ ++ + W  P  NGG  I  Y +E   V 
Sbjct: 6353 EFSVPTDPQAAMDPILPPGPPVPKIV-DVTNTTIDISWQPPLYNGGGEILGYHVERCLVG 6411

Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
             K W +         ++ +  + E  +   R+ A N  G   P  ++ V+ ++    P
Sbjct: 6412 EKDWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEPEEAP 6469



 Score =  171 bits (417), Expect = 1e-40
 Identities = 216/903 (23%), Positives = 355/903 (39%), Gaps = 56/903 (6%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            E P + F + +   +++ A     L   +    +    + K     D E   + +++K  
Sbjct: 6467 EAPGVEFDISVRNGVIIRAGETLRLPAVVTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSS 6526

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
            TL I+K    D   Y     +   T    +KV+V++ P  +VD +     K+   +T   
Sbjct: 6527 TLSIKKALRTDHGIYQITGTNPSGTKSVSVKVDVMDVPGPVVDLKTVNVSKKMISLTWSD 6586

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG-H 1368
                       ++V  K  K   + +P ++  +    I  + + +  ++++   N  G  
Sbjct: 6587 PLDNGGSDIMGYVVERKDAKMHIYRQP-LEVAACKCDIVGLLDGEEYMFRVVARNKFGLG 6645

Query: 1369 ADVEMN-VTILDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
            A VE+  V  +D    PS P K    E   ++I + W+ P + G S II Y +E    D+
Sbjct: 6646 APVELGPVLAVDPKGVPSAPEKLRYTERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDS 6705

Query: 1425 TEW-ISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
             E+ ++ +N+ K  T +++NL  N  + FR  AVNEV   + S+       I+E +  SP
Sbjct: 6706 NEYDVANRNLCKDLTITLENLTENMMFDFRVKAVNEVGNGEPSKAISVN--IQEDE-NSP 6762

Query: 1483 TVE--KPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE----NR 1532
            TV+  K  K+  I       IE+     G+P P   W ++G  +   T   T E    NR
Sbjct: 6763 TVKWMKFFKSDAIIVRKGAAIEIPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINR 6822

Query: 1533 XXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV--ITISNEDIKQKHKV 1586
                               YK  A N  G  + +  V I  +P+    I   DIK +   
Sbjct: 6823 QTITTKIGIPESVRQDTGMYKLTATNTRGVGQRTMRVDILDRPLPPRNIVVSDIKAE-SC 6881

Query: 1587 GDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
               W       G      ++  ++ +K ++D +  +T         + +L+   + ++ I
Sbjct: 6882 YLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWD-QLTCCIMDRRYGVYKLEAYGTYQFQI 6940

Query: 1646 EASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
            +A N  G S    S +V LK  +  P  P+ P I+   +R S+ + W+PP D+GG  +  
Sbjct: 6941 KAENKYGISDGCESEKVVLKDPFGLPGPPQRPRIISH-TRSSMVVTWEPPKDNGGSTIQG 6999

Query: 1701 YAIEKHEPDNNRWIKV--ADVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            Y +EK E     W +V  A V +       Y +  L E  EY FRV+AQN  G     E+
Sbjct: 7000 YWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEA 7059

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814
               V       P               SV ++W P +++GGSPI  Y VE++ EG  +WK
Sbjct: 7060 TECVFALDPRNPPSQPPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWK 7119

Query: 1815 XXXX----XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
                           +  L  N   +FRI A N  G S P      I +   L  P    
Sbjct: 7120 RINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPSPRTSDIIVQDILEEPVITI 7179

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV---KGKSWTKIVTVGGSVHEHCI 1927
            +    E  +         P +  G P+ N   EF      + K+    + V   +     
Sbjct: 7180 DVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTAPSEKKNERHTLPVDSDISSSDT 7239

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMT 1985
             ++    E     S    +  +    ++ V++     V   P AP +I +  +       
Sbjct: 7240 TSVVTIPESKLHHSGRYIITANNQAGTKIVKV--RVNVLDLPGAPKDITISDITRGTCRL 7297

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
            SW  P+ DGG  +  Y I  + V    W +V      T    + DL E   Y+ RI A N
Sbjct: 7298 SWKPPDCDGGDRIKSYFIEKKTVEGKAWTKVNPA-CTTQSLVVPDLIEGQEYLFRIRAEN 7356

Query: 2046 EIG 2048
              G
Sbjct: 7357 RFG 7359



 Score =  171 bits (415), Expect = 2e-40
 Identities = 187/877 (21%), Positives = 373/877 (42%), Gaps = 46/877 (5%)

Query: 830  AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886
            A P  F+   Q+I ++E  +I    V     +P  +IT W ++   I  S       DG+
Sbjct: 2655 AVPLKFVKELQDIVLQEAESIGSSAVFECQISPSTAITTWMKDGSNIRESPKHKFTSDGK 2714

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            + +L I +V    D+G+Y CVA     + +  A++ ++   V F K+L++     +G+ +
Sbjct: 2715 DRKLQIIDVQLS-DTGEYTCVAKLGNKEKTSTAKLVVEELPVKFTKNLEEETSVLKGQPM 2773

Query: 947  ILECQTSHTVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
             L C+ S      W  N KE+  +  + +I   G             D GV  C  ++ +
Sbjct: 2774 YLTCELSKDKDVVWKKNGKELKEIPGKIQINIIGLQRAVTIQDMNDDDAGVYTCECENIK 2833

Query: 1006 TSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWER-DGEIIKPKKNKY 1063
            T T + V E + +++ K L+D  VK K  A  + E+  ET +  W + + EI     +K 
Sbjct: 2834 TETNVKVIEIVRDWLVKPLRDQHVKPKSTATFKGELFKETPNWKWYKGNDEIPNEPTDKT 2893

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
            + +K G    L I+N    D  EY+  +      A++T+ E   EI+  L + +V +  +
Sbjct: 2894 EVKKEGKEITLTIKNAQPDDVAEYAVEVEGRRYAAKLTLGEREAEILKPLASVEVVEKTE 2953

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            A FE E+++ D    W   G  +  S    +  +G K+ L I +  LD AGE + +  N+
Sbjct: 2954 ANFETEISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRFLTIKNVQLDQAGEVTYQALNA 3013

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
              +A+L V+E    F+++L ++  V  +    D  L+ ++P     V W+  +  I+ ++
Sbjct: 3014 VTSAMLNVKEGDAFFSVKLQDYTAVEKDEVTFDCELSRDVP-----VKWFHNEIEIKASK 3068

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300
              T+  + K+R L ++K    D+  Y C     K+++ L +E  +   K+V       + 
Sbjct: 3069 MVTIKVEGKRRILNLKKVENKDKGVYVCDCGTDKTSSNLNIEARDI--KVVKPIYGVELF 3126

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
             G      V+       + +W +   ++      +   D    +LT+     + +G    
Sbjct: 3127 DGETARFEVEISE-DDVHGQWKLKGDVLSASPDVEIIEDGAKHTLTLYNCRVSQSGEVTF 3185

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
            +  N    A++++    +    P     + E D +   I     E +  +  + ++   Q
Sbjct: 3186 QGANAKCSANLKVKELPISFVMPLSDVQVYEKDEARFEI-----ELSREAKTVRWLKGSQ 3240

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
            E+   E   +  + + +  I  +K + +Y   A  + E +     + T    VI+  +++
Sbjct: 3241 ELKVDEKFEI--LAEGKRHILVVK-SVAYEDEAKYMFEAE----DKRTSAKLVIQGIRLE 3293

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXX 1539
                 +P+K++T +  E  E + I     + +VTWY++  +L  +K  +           
Sbjct: 3294 ---FVRPIKDVTVKERETAEFS-IELSHEKIQVTWYKNDVRLHPSKVVHMSEHGKIHTLS 3349

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                       I     G+   + +  ++ +P  T   +D     K  DE ++   +   
Sbjct: 3350 FKEVSIDDTSLIKVEALGKTSEAMLTVLEGEPYFTTKLQDYTAVEK--DEVVLMCEVSK- 3406

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE--ASNTAGTSSVE 1657
               +V W+K+ N++   K   I    K  ++ +K+ ++ +  +Y  +  +  TA   ++E
Sbjct: 3407 SSAQVKWFKDTNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIE 3466

Query: 1658 -----VTLKVYD-KPSKPEGPVIMREISRESVTIEWK 1688
                 ++  +Y  + ++ E      EIS E V   WK
Sbjct: 3467 ERDIKISRPLYSVEVTETETARFETEISEEDVHGHWK 3503



 Score =  168 bits (408), Expect = 2e-39
 Identities = 175/769 (22%), Positives = 322/769 (41%), Gaps = 45/769 (5%)

Query: 1312 QAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
            + F    D+WI ++K+ IK        + +K         EN  AG  K  +E      D
Sbjct: 5282 ERFDPETDKWIKSNKLPIKDTTFRVKGLPTKKKYKFRVLAENL-AGQGKPSVET-----D 5335

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
              +    +D P  PGKP + +I  +S ++ W  PE+ G + I  Y++E Q+  T EW+ V
Sbjct: 5336 PVLIKDPIDPPWAPGKPFVKDIAKTSADLQWTRPEHDGGAKIESYIIELQKTGTEEWVRV 5395

Query: 1431 -KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
             +++  T+ S++ L     Y FR  A+N    S+ S+ ++   V+ + ++  P   + L+
Sbjct: 5396 AEDVPTTEHSLKGLMEKQEYSFRVKAINVAGESEPSDPSD--PVVCKERLYVPNPPRWLE 5453

Query: 1490 NIT-TEPNEDIELT--CIFGGVPQPK-VTWYRDGKKLK------TAKATYENRXXXXXXX 1539
             +  T+ N D++ T     GG P    V   RD ++        T K T           
Sbjct: 5454 VVNITKINCDLKWTEPDSDGGSPITNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGS 5513

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       +  ++  E+E S +         P   ++  ++ ++H V  +W      
Sbjct: 5514 LYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYALTVVEVSKRH-VDLKWEPPNSD 5572

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--- 1653
             G P  + +  K   K+      +  T    S  R+ ++      ++ + A N AG    
Sbjct: 5573 GGRPITKYVIEKK-EKVGTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHP 5631

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            S   V + + D  S P  P+ ++  + SRE + I WK P  +GG  +T Y +E  E +  
Sbjct: 5632 SEPTVIMTIEDAISPPSPPLEVKIVDASREHINITWKAPEKNGGSPITGYHVELSEAETE 5691

Query: 1712 RWIKVADVD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSX 1769
            +W+++     +++     + +    +Y+ RV A N +G S+  E S+ +  K     P+ 
Sbjct: 5692 KWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTI 5751

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQ 1827
                     ++ E + I   P        ++  K   E+K E +              + 
Sbjct: 5752 DVATQDIVVVEGEKMDIK-IPYRAIPKPSMVWKKGDTELKTEDRL-TLTCELNRVHLELL 5809

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
            K        + +   N +G+    T    +T+   +  P Q ++   SE T  S  + W 
Sbjct: 5810 KCKHEDAGVYTVTLENSLGS---VTGTVSVTV---IGLPGQCKDISPSELTKNSCKISWE 5863

Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
             PE++GGSPI +Y++E +  + K++  +++ G +V    ++++    E  FR+ A N +G
Sbjct: 5864 PPENDGGSPILHYVLERREAQKKTFLPVMS-GENVLSFVVKDLMLNSEYHFRVKAVNKIG 5922

Query: 1948 VSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
                 E ++ V +E+    P PP     +    ++I +T W  P +DGG P+ GY I   
Sbjct: 5923 SGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSITVT-WMAPPYDGGCPITGYIIEKI 5981

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            +     +       V    + +  L+E   Y  R+ A N  G S+P  S
Sbjct: 5982 EKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRS 6030



 Score =  167 bits (406), Expect = 3e-39
 Identities = 191/825 (23%), Positives = 318/825 (38%), Gaps = 66/825 (8%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283
            ++TW K   V+   ++  + ++     L+I+     D  +Y     ++    +  + V V
Sbjct: 9084 EITWTKDARVLGRDKRTEMNNNFPLVELVIQDAVRADYGKYAIQAKNSSGQAQATIIVNV 9143

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH------TKPS 1337
            ++ P    + +  Y  K     + +V ++         I N KI  +C+       T  S
Sbjct: 9144 LDIPGACQNLKVAYVTKD----SCMVSWENPEDNGGTEITNYKI--ECRQPSQRGWTVVS 9197

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPN---ILE 1391
             D     +    V+N +   +++  EN  G     + +  V  +D    PG+P    I E
Sbjct: 9198 SDCTKRLVKAPLVQNCEY-FFRVSAENKIGAGPPTESKTPVLAVDPVEKPGEPENFQITE 9256

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449
            I  + + + W +PE  G S  + Y VE +  +  EW  +    I +T         N  Y
Sbjct: 9257 IGKTFVFLKWKKPEYDGGSRNLAYHVEKKPKEADEWERLHKGAIKETYFMADRCIENQIY 9316

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
            +FR    NE   S+   T E   ++KE  +Q     K +  +  +  + + +     G P
Sbjct: 9317 QFRVQTKNEGGESNWVTTAEV--LVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKP 9374

Query: 1510 QPKVTWYRDG------KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
            QP+V W ++G      K L+    T  N                Y   A N  G      
Sbjct: 9375 QPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEA 9434

Query: 1564 VVGIQQKP--VITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             V +  +P  +  +   DI   + K+   W +     G      I  K   K      ++
Sbjct: 9435 KVNVLDRPGPIRDLKVSDISIDRCKLA--WEIPEDDGGCEIYNYIIEKCEAKRGVWSIHS 9492

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVE----VTLKVYDKPSKPEGPVIM 1675
                  T+  ++  L   +   + + A N  G   +VE    +    + +P  P+ P + 
Sbjct: 9493 AAII--TNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESIIARTQFSRPGAPDAPEVT 9550

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
            + I+++++ + W  P +DGG  +T Y +EK E    RW  V           +  L  N 
Sbjct: 9551 K-ITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVKSPYAGTQMTVTSLLPNH 9609

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEK 1793
            EY FRV A+N +G  +A  S+P    TA D   P               S+ + W     
Sbjct: 9610 EYQFRVKAENEIGVGDA--SKPSRTFTARDPVEPPGPVSNLKVTDSSKTSITLAWTKPTY 9667

Query: 1794 NGGSPIIDYKVEI--KQEGKK----WK---XXXXXXXXXARIQKLSINTTYQFRI----Y 1840
            +GG+P+I Y VEI  K  GKK    WK              +  L     Y+FR+     
Sbjct: 9668 DGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFRVTRDDS 9727

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
             +  +  S P          K L  P       V++ T  S  L W+ PE++GGS +T+Y
Sbjct: 9728 GKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTDMTMSSCNLTWSPPETDGGSNVTHY 9787

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
            I+E + +  K+W    TV  +V +    I N+    E  FR+ A N  G  +P  +    
Sbjct: 9788 IVEKREIDRKTW---ATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVTPKSY 9844

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            L         P   +++  +  N     W  P  DGGA + GY I
Sbjct: 9845 LASDPVSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVI 9889



 Score =  165 bits (401), Expect = 1e-38
 Identities = 175/783 (22%), Positives = 305/783 (38%), Gaps = 48/783 (6%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E +PP F KK      + G+ +  EC +   P     W   G EI   + + +       
Sbjct: 220  EEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRII----SR 275

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               S L++ +  K   G Y+  A N+ G  +    L I     EP + +  L ++ +   
Sbjct: 276  QTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA--SEPARFLRKLSNISIPMS 333

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLK 806
            + + L  +  G+ +  +TW K+ K + A    +   T +   L+  +  D    G+Y+ +
Sbjct: 334  QKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGIYSCE 393

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
              N+ G     A +T         EP  F+ +  ++++     ++L    T  P   +TW
Sbjct: 394  VSNAFGREICHATVTAV------TEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTW 447

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            Y++ + +  S          +  L   +  +   +G Y C  SN  G     A+V    E
Sbjct: 448  YKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTE 507

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRXXX 983
               FVK L         + + LEC  +    +   WY + K++ +   +   +       
Sbjct: 508  PARFVKKL-TDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCIL 566

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAI---LEVE 1039
                       G   C V +   +   +    I  F    + + ++K+K VA+   L++E
Sbjct: 567  ECLHECNDATPGKYSCEVSNSIGTD--ICHANITTFTEPARFELKLKDKQVAMSKNLKLE 624

Query: 1040 INSETAD---VVWERDGEIIKPKKNKYDFEKRGHIRKL-YIRNTSVHDEGEYSCILRD-- 1093
                 A    V W +DG+ +     +Y+    G+   L  +   +    G+YSC + +  
Sbjct: 625  CTFTGAPKIFVTWYKDGKQLY-ASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSY 683

Query: 1094 --ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSN 1150
              + C AEVT    P   +  L +Q + +G K   E      G   V W+KDG +   S 
Sbjct: 684  GKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASY 743

Query: 1151 HIQLTIDGKKQKLK-IYDCDLDDAGEYSCEV----GNSKCTAILTV-EEPSI--NFTLRL 1202
                 + G    L+ +++CD +  G+YSCEV    G+  C A++T+  E  I   FT + 
Sbjct: 744  RCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKP 803

Query: 1203 PEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
             E I         L   +   + L V WYK    I  ++ + +        + +RK T  
Sbjct: 804  SEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVT 863

Query: 1262 DQCEYTCVLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
            D   YTC   +   T   +V V     + PP      +   +  G  + L       P  
Sbjct: 864  DSGVYTCSASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPV 923

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              +W+ + + +     TK +    +A+L I +   TDAG Y  +  NN G    +  VTI
Sbjct: 924  KIQWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTI 983

Query: 1378 LDK 1380
             DK
Sbjct: 984  KDK 986



 Score =  163 bits (396), Expect = 5e-38
 Identities = 182/744 (24%), Positives = 307/744 (41%), Gaps = 69/744 (9%)

Query: 1179 EVGNSKCTAILTV--EEPSINFTLRLPEFILVPAN-TDAYLTVEIPDETLDVT-----WY 1230
            EVGN + +  ++V  +E   + T++  +F    A        +EIP E + +      W 
Sbjct: 6741 EVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIEIPAEIVGLPLPTFEWT 6800

Query: 1231 KKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
            K   VI+  TE  TL S+   R  I  K    +       +    +T    V        
Sbjct: 6801 KNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGMYKLTATNTRGVGQRTMRVD 6860

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTI 1347
            I+D     R    SD+     Y  +  P D     + + I++K   +K   D    +  I
Sbjct: 6861 ILDRPLPPRNIVVSDIKAESCYLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWDQLTCCI 6920

Query: 1348 K-------KVENTDAGIYKLRLENNCGHAD-VEMNVTILDKP----SPPGKPNILEIDSS 1395
                    K+E      ++++ EN  G +D  E    +L  P     PP +P I+    S
Sbjct: 6921 MDRRYGVYKLEAYGTYQFQIKAENKYGISDGCESEKVVLKDPFGLPGPPQRPRIISHTRS 6980

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN-------SS 1448
            S+ + W+ P++ G STI  Y +E +E     W  V     T+ +++ L+ N       + 
Sbjct: 6981 SMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAE 7040

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI---- 1504
            Y+FR  A N   +   SE TE    +     ++P  + P   +T +    + L+      
Sbjct: 7041 YKFRVMAQNAAGVGPPSEATECVFALDP---RNPPSQPPAPVVTDKSPSSVSLSWTPPDR 7097

Query: 1505 FGGVP-QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC----IAFNDHGEV 1559
             GG P +  +   +D    +  +    ++                KC    +A N  GE 
Sbjct: 7098 DGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGES 7157

Query: 1560 ETS------CVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNG-- 1610
            E S       V  I ++PVITI     +  + + G    + A I G P P V W  +G  
Sbjct: 7158 EPSPRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTA 7217

Query: 1611 -NKLENDK-----EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             ++ +N++     + +I++ + TSV+ I E K  HS +Y I A+N AGT  V+V + V D
Sbjct: 7218 PSEKKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIVKVRVNVLD 7277

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             P  P+  + + +I+R +  + WKPP  DGG  +  Y IEK   +   W KV +     +
Sbjct: 7278 LPGAPK-DITISDITRGTCRLSWKPPDCDGGDRIKSYFIEKKTVEGKAWTKV-NPACTTQ 7335

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
            +  +  L E  EY+FR+ A+N  G+       E    +  +  P           +    
Sbjct: 7336 SLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKARDPIH-PPDPPTRVKIIDVSKGI 7394

Query: 1784 VYITWFPSEKNGGSPIIDYKVE--------IKQEGKKWKXXXXXXXXXARIQKLSINTTY 1835
            V +TW P + +GG+P+  Y +E         +QE  +            +++ L     Y
Sbjct: 7395 VTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQCNRRDIDTTTFKVEDLHEGAEY 7454

Query: 1836 QFRIYARNEIGTSLPYTSDDKITI 1859
            +FR+ A NE+G S P ++   I +
Sbjct: 7455 EFRVKAVNEVGASRPSSTAGPIIV 7478



 Score =  161 bits (391), Expect = 2e-37
 Identities = 164/679 (24%), Positives = 296/679 (43%), Gaps = 46/679 (6%)

Query: 695  LKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751
            L+I +V+    G YT VA   N+E  ++  +V+     E+ P +  + L+    V +G+ 
Sbjct: 2718 LQIIDVQLSDTGEYTCVAKLGNKEKTSTAKLVV-----EELPVKFTKNLEEETSVLKGQP 2772

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLKA 807
            + L+ ++  +    + W KN K +K +P K      G   ++TI +     D GVYT + 
Sbjct: 2773 MYLTCEL--SKDKDVVWKKNGKELKEIPGKIQINIIGLQRAVTI-QDMNDDDAGVYTCEC 2829

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            EN     +T   + V E   +    PL     ++  VK K T      + +   P+  WY
Sbjct: 2830 EN----IKTETNVKVIEIVRDWLVKPL-----RDQHVKPKSTATFKGELFKE-TPNWKWY 2879

Query: 868  RNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            + N+ I   P++      +G+ I L I N   + D  +Y   A    G+  + A++T+  
Sbjct: 2880 KGNDEIPNEPTDKTEVKKEGKEITLTIKNAQPD-DVAEY---AVEVEGR-RYAAKLTLGE 2934

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
             +   +K L  S E  E      E + S   V  +W    + ++     +I  EG     
Sbjct: 2935 REAEILKPL-ASVEVVEKTEANFETEISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRFL 2993

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                      G +     +  TS ML VKE    F  KLQD+   EKD    + E+ S  
Sbjct: 2994 TIKNVQLDQAGEVTYQALNAVTSAMLNVKEGDAFFSVKLQDYTAVEKDEVTFDCEL-SRD 3052

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W  +   IK  K     +  G  R L ++     D+G Y C    +  ++ + +  
Sbjct: 3053 VPVKWFHNEIEIKASK-MVTIKVEGKRRILNLKKVENKDKGVYVCDCGTDKTSSNLNIEA 3111

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
               +++  +   ++  G  A FE+E+++ D   +W   G  +  S  +++  DG K  L 
Sbjct: 3112 RDIKVVKPIYGVELFDGETARFEVEISEDDVHGQWKLKGDVLSASPDVEIIEDGAKHTLT 3171

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            +Y+C +  +GE + +  N+KC+A L V+E  I+F + L + + V    +A   +E+  E 
Sbjct: 3172 LYNCRVSQSGEVTFQGANAKCSANLKVKELPISFVMPLSD-VQVYEKDEARFEIELSREA 3230

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              V W K    ++  EKF ++++ K+  L+++    +D+ +Y     D +++ KL ++ +
Sbjct: 3231 KTVRWLKGSQELKVDEKFEILAEGKRHILVVKSVAYEDEAKYMFEAEDKRTSAKLVIQGI 3290

Query: 1285 --EFPPKIVDYEREYRIKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
              EF   I D   + R      + L  +  Q     ND  +  SK++   +H       K
Sbjct: 3291 RLEFVRPIKDVTVKERETAEFSIELSHEKIQVTWYKNDVRLHPSKVVHMSEH------GK 3344

Query: 1342 SASLTIKKVENTDAGIYKL 1360
              +L+ K+V   D  + K+
Sbjct: 3345 IHTLSFKEVSIDDTSLIKV 3363



 Score =  161 bits (391), Expect = 2e-37
 Identities = 183/758 (24%), Positives = 305/758 (40%), Gaps = 52/758 (6%)

Query: 1338 IDSKSASLTIKKVENTDAG---IYKLRLENNCGHADVEMNV---TILDKPSPPGKP--NI 1389
            ++S   S    KVE    G   ++++  EN  G  +  +       +D   PPG P   I
Sbjct: 6318 VNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGEFSVPTDPQAAMDPILPPGPPVPKI 6377

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNS 1447
            +++ +++I+I W  P   G   I+ Y VE   +   +W+          + ++  L   +
Sbjct: 6378 VDVTNTTIDISWQPPLYNGGGEILGYHVERCLVGEKDWVRCTEFRCKDRKYTVTGLTEGA 6437

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK---NITTEPNEDIELTCI 1504
             Y  R YAVNE     A   TE  +  KE + ++P VE  +     +     E + L  +
Sbjct: 6438 DYNLRVYAVNEGG-HGAPGMTEPVQA-KEPE-EAPGVEFDISVRNGVIIRAGETLRLPAV 6494

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVET 1561
              G P P+V W +DG +        E                    Y+    N  G    
Sbjct: 6495 VTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPSGTKSV 6554

Query: 1562 SCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
            S  V +   P  V+ +   ++ +K  +   W       G    +++ Y    K      Y
Sbjct: 6555 SVKVDVMDVPGPVVDLKTVNVSKK-MISLTWSDPLDNGG---SDIMGYVVERKDAKMHIY 6610

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEV-TLKVYDKPSKPEGPVIMR- 1676
                +       I  L       + + A N  G  + VE+  +   D    P  P  +R 
Sbjct: 6611 RQPLEVAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDPKGVPSAPEKLRY 6670

Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNEN 1734
             E ++ ++T+ W+ P  DGG  +  Y IEK   D+N + +   ++ +D+ T  ++ L EN
Sbjct: 6671 TERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDSNEYDVANRNLCKDL-TITLENLTEN 6729

Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX--XXXXXXXXIDNESVYITWFPSE 1792
              + FRV A N VG  E  ++  + I+   + P+            I  +   I   P+E
Sbjct: 6730 MMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIE-IPAE 6788

Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
              G  P+  ++   K      +           I + +I T        R + G     T
Sbjct: 6789 IVG-LPLPTFEWT-KNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGM-YKLT 6845

Query: 1853 SDDKITIGKT------LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
            + +   +G+       L  P  PRN VVS+  + S  L W  PE NGGS +TNYI+E + 
Sbjct: 6846 ATNTRGVGQRTMRVDILDRPLPPRNIVVSDIKAESCYLTWDAPEDNGGSDLTNYIVEKRD 6905

Query: 1907 VKGKS--WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
               K   W ++ T       + +  ++      F+I AEN  G+S   ES+ V L+    
Sbjct: 6906 ASKKKSDWDQL-TCCIMDRRYGVYKLEAYGTYQFQIKAENKYGISDGCESEKVVLKDPFG 6964

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT- 2023
            +P PP  P  I    S++V+T W  P+ +GG+ + GY +  R+     W  V +  V   
Sbjct: 6965 LPGPPQRPRIISHTRSSMVVT-WEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAPVTKP 7023

Query: 2024 ----LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
                L++N+  L E   Y  R+ A+N  G+  P E+ E
Sbjct: 7024 AVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATE 7061



 Score =  156 bits (378), Expect = 7e-36
 Identities = 120/446 (26%), Positives = 200/446 (44%), Gaps = 35/446 (7%)

Query: 1642 KYTIEASNTAGTSSV-EVTLKVY-----DKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
            K+ + A N AG     E T  V+     + PS+P  PV+  + S  SV++ W PP  DGG
Sbjct: 7042 KFRVMAQNAAGVGPPSEATECVFALDPRNPPSQPPAPVVTDK-SPSSVSLSWTPPDRDGG 7100

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIAQNPVGFSE-A 1752
              +  Y +E  +  ++ W ++   D+ + T  Y +  L EN +  FR++A N  G SE +
Sbjct: 7101 SPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPS 7160

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKVEIKQEGK 1811
              +  I+++  L+ P           ++  +      P+  +G   P + ++ +     +
Sbjct: 7161 PRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTAPSE 7220

Query: 1812 KWKX----------XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            K                       I +  ++ + ++ I A N+ GT +      K+ +  
Sbjct: 7221 KKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIV-----KVRVN- 7274

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
             L  P  P++  +S+ T  +  L W  P+ +GG  I +Y IE KTV+GK+WTK V    +
Sbjct: 7275 VLDLPGAPKDITISDITRGTCRLSWKPPDCDGGDRIKSYFIEKKTVEGKAWTK-VNPACT 7333

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVGS 1980
                 + ++ E  E +FRI AEN  G    T + +  +       P PPT  ++I  V  
Sbjct: 7334 TQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKARDPIHPPDPPTR-VKIIDVSK 7392

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIA-----IRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
             IV  +W  P+ DGGAP+  YNI           +  W +  + D++T  F + DL E  
Sbjct: 7393 GIVTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQCNRRDIDTTTFKVEDLHEGA 7452

Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKV 2061
             Y  R+ A NE+G S P  +  P  V
Sbjct: 7453 EYEFRVKAVNEVGASRPSSTAGPIIV 7478



 Score =  150 bits (364), Expect = 4e-34
 Identities = 161/598 (26%), Positives = 264/598 (44%), Gaps = 80/598 (13%)

Query: 632  IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            IPPTF+KKP     D EG  + LE R+       + W    +EI   +   V+ +S++ +
Sbjct: 795  IPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAV 854

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
             C  L+   V     G YT  A N  G AS  +V+ I T +K PP    PLK M V +GE
Sbjct: 855  MC--LRKATVT--DSGVYTCSASNEAGTASFQVVVNI-TEQKRPPTFDIPLKPMTVSEGE 909

Query: 751  SVILSAQVVGNPRPTITWCKNNKPV-KALPTKS---DGDTHSITILKPKKVKDEGVYTLK 806
             + LS  V G+P   I W K+ + V  +  TK    DG T ++ I +  K  D G Y  K
Sbjct: 910  RLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTFVDG-TATLEINQASKT-DAGDYLCK 967

Query: 807  AENSEGIAETSAVITVEE------------PTEENAEPPL----FINRFQEITVKEKGTI 850
            A N+ G   +   +T+++            PT   A   L    FI   + I + EKGT 
Sbjct: 968  ATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTA 1027

Query: 851  KLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              +A+V  +P+P++ W +     ++    I     G+  +L I  V ++ DSG Y+CVAS
Sbjct: 1028 TFIAKVGGDPIPNVKWMKGKWRQMTHGGRINIQQKGQESKLEIKEV-TKSDSGQYRCVAS 1086

Query: 910  NSAGKSSHGARVTIDVEK------VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN 963
            N  G+      + +D +K      V   K   K    +E K + +  +    V  K Y  
Sbjct: 1087 NKHGEIECSTDLNVDEKKESGPEVVKLKKTPSKQKSPKEDKDIDI-VELLRNVDPKEYEK 1145

Query: 964  KKEISGM-DHREIIQ-----EGRXXXXXXXXXXXXDVG-VIKCIVKDQETSTMLVVKETI 1016
               + G+ D R ++Q     +              D+  ++  + +  E S  + + + I
Sbjct: 1146 YARMYGITDFRGLLQAIEFLKKEKGEESGRPEEDEDLAKLVSDLQRRMENSEPVTLLKDI 1205

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             +     Q  ++ ++ V   E+++N     + W +D + ++   +KYD +  G  + L I
Sbjct: 1206 TD-----QTTQLNKEAVFECEIKVNYPEITLAWYKDTQKLE-TNDKYDIKLVGDRQILKI 1259

Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136
            +N+   D+ +++                       R+QN  VN+   ATFE EL+  +A+
Sbjct: 1260 KNS---DQIQFT----------------------KRIQNIVVNERQSATFECELSFDNAV 1294

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-----EVGNSKCTAIL 1189
            V W+KD  E++ S       +G++  + I +   DD G YS       VG +K TA L
Sbjct: 1295 VTWYKDAWELKESLKYTFKCEGRRHFMIIRNVTADDEGVYSVIARLEPVGETKSTAEL 1352



 Score =  149 bits (362), Expect = 6e-34
 Identities = 158/746 (21%), Positives = 291/746 (39%), Gaps = 39/746 (5%)

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN---VTILD---KPSPPGKPNILE 1391
            + ++  + T+  V      I+++R EN  G          V I+D   +PSPP   N   
Sbjct: 4605 VKAEDLTATLSDVVENKEYIFRVRAENKAGIGQPSAATDPVKIMDPIERPSPPLNFNYTN 4664

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSY 1449
                S+ + W+ P + G S I  Y++E  E  T +W+  + +        +  LK    Y
Sbjct: 4665 QTRDSVQLSWETPISNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLYYRVSGLKFGQKY 4724

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKN--ITTEPNEDIELTCIFG 1506
             +R  A N   +S+ ++      ++ +     PT++    KN      PN  I +     
Sbjct: 4725 HYRVCAENAAGVSEPADAIG--PLLADDPHVGPTIDLSGFKNGLEVIVPNALI-IKVPIT 4781

Query: 1507 GVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            G P PK  W    K+L    + +  T                   Y     ND   V   
Sbjct: 4782 GYPVPKPKWTFGDKELTAGDRVSMVTKPTYTELVVAPSVRPDKGTYTLQLENDVTSVSGE 4841

Query: 1563 CVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-N 1620
              V +   P      +  +  +H V   W       G P   V  Y    +  + K +  
Sbjct: 4842 IEVNVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSP---VSGYNVEKREVSRKTWVK 4898

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIM-- 1675
            + +  +     + ++       +++ A N  G      ++  + V    + P+ P ++  
Sbjct: 4899 VISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDPPELLKW 4958

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
            R+ S +S+ + W+PP  DGG  +  Y ++K +   ++W    D   +++ + +  L E  
Sbjct: 4959 RDKSAKSIFLLWEPPRYDGGAAVKGYIVDKCQRGTDKWEACGDPIPELK-FQVTGLIEGQ 5017

Query: 1736 EYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
             Y +RV A N +G S   ++ + I+     + P           +   +      P++  
Sbjct: 5018 WYAYRVRAVNRLGASRPCKATDEILAVDPKEPPEIQLDAKLLAGLTARAGTKIDLPADVL 5077

Query: 1795 GG-SPIIDY-KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
            G   P + + K ++  + ++ +         + +  ++  T      Y    + TS   T
Sbjct: 5078 GKPEPRVKWTKADLVLKPEE-RITIDTKPGHSTLS-IANTTRSDTATYIIEAVNTSGRAT 5135

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
            +   + I   L  P  P  F +SE T+ S  L W  P  +GGSP+ NYI+E +    + W
Sbjct: 5136 ATVDVNI---LDKPGPPAAFDISEITNESCCLAWNAPRDDGGSPVANYIVEMRPTDKEEW 5192

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
             K+            + +  K E +FR+SAEN  G+  P E   +  +     P  PT  
Sbjct: 5193 QKLSATIKQTAFKATKLVPLK-EYVFRVSAENQYGIGTPAEHVPIVAKYSFDTPGAPTR- 5250

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            ++   +  + V  +W  P+ DGG+P+ GY +   D     W++  K+ +    F ++ L 
Sbjct: 5251 VQPSDITRDAVTLTWYEPDEDGGSPITGYWVERFDPETDKWIKSNKLPIKDTTFRVKGLP 5310

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEP 2058
                Y  R+ A N  G  +P    +P
Sbjct: 5311 TKKKYKFRVLAENLAGQGKPSVETDP 5336



 Score =  141 bits (342), Expect = 2e-31
 Identities = 120/439 (27%), Positives = 191/439 (43%), Gaps = 31/439 (7%)

Query: 1643 YTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLE 1697
            + + A N AG    S+    +K+ D   +P  P+     +  R+SV + W+ P+ +GG  
Sbjct: 4625 FRVRAENKAGIGQPSAATDPVKIMDPIERPSPPLNFNYTNQTRDSVQLSWETPISNGGSM 4684

Query: 1698 LTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
            +T Y IEK E   ++W++  A +  D+  Y +  L    +Y +RV A+N  G SE  ++ 
Sbjct: 4685 ITGYIIEKCEDGTDKWLRCNARLCPDLY-YRVSGLKFGQKYHYRVCAENAAGVSEPADA- 4742

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
              +     D P            +   V +   P+      PI  Y V       KW   
Sbjct: 4743 --IGPLLADDPHVGPTIDLSGFKNGLEVIV---PNALIIKVPITGYPVP----KPKWTFG 4793

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIG-----KTLTPPSQ 1868
                    R+  ++   TY   + A   R + GT      +D  ++        +  PS 
Sbjct: 4794 DKELTAGDRVSMVT-KPTYTELVVAPSVRPDKGTYTLQLENDVTSVSGEIEVNVIACPSA 4852

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
            P++F V+E T   V L W  PE +GGSP++ Y +E + V  K+W K+++ G    E+ + 
Sbjct: 4853 PKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVEKREVSRKTWVKVIS-GVQDLEYTVT 4911

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
            ++ E  E +F + A N  G   P    + V +   ATVP PP   L+ R   +  +   W
Sbjct: 4912 DVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDPPEL-LKWRDKSAKSIFLLW 4970

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              P +DGGA + GY +         W   G   +  LKF +  L E   Y  R+ A N +
Sbjct: 4971 EPPRYDGGAAVKGYIVDKCQRGTDKWEACGD-PIPELKFQVTGLIEGQWYAYRVRAVNRL 5029

Query: 2048 GLSEPLE-SDEPFKVIPGE 2065
            G S P + +DE   V P E
Sbjct: 5030 GASRPCKATDEILAVDPKE 5048



 Score =  139 bits (337), Expect = 7e-31
 Identities = 121/574 (21%), Positives = 231/574 (40%), Gaps = 30/574 (5%)

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375
            P   ++V  + +++          K    T+  +      ++++  EN  G ++  E+  
Sbjct: 5476 PITNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELED 5535

Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
            ++L K     P PP    ++E+    +++ W+ P + G   I  YV+E +E   T W+  
Sbjct: 5536 SVLAKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKS 5595

Query: 1431 KNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
               +  ++   + ++   +  +F+  A NE  +   SE T    +       SP +E  +
Sbjct: 5596 GKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPSPPLEVKI 5655

Query: 1489 K-------NIT---TEPNEDIELTCIFGGVPQPKVT-WYRDGKKLKTAKATYENRXXXXX 1537
                    NIT    E N    +T     + + +   W R   +    +  ++       
Sbjct: 5656 VDASREHINITWKAPEKNGGSPITGYHVELSEAETEKWMRINPR-PVKELRFKAEEGIIP 5714

Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                         I  +D  E+            P I ++ +DI      G++  +    
Sbjct: 5715 EKKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTIDVATQDIVVVE--GEKMDIKIPY 5772

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
              IP P ++W K   +L+ +    +T +     + + + K   +  YT+   N+ G+ + 
Sbjct: 5773 RAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTG 5832

Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
             V++ V   P + +  +   E+++ S  I W+PP +DGG  +  Y +E+ E     ++ V
Sbjct: 5833 TVSVTVIGLPGQCKD-ISPSELTKNSCKISWEPPENDGGSPILHYVLERREAQKKTFLPV 5891

Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXX 1775
                 +V ++ ++ L  N EY FRV A N +G  E LE   P++I+     P        
Sbjct: 5892 MS-GENVLSFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAG 5950

Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWK--XXXXXXXXXARIQKLSIN 1832
                 N S+ +TW     +GG PI  Y +E I+++G +++             +  L+  
Sbjct: 5951 LNPTSN-SITVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEG 6009

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
              YQFR+ A N  G S P  S   I     + PP
Sbjct: 6010 KEYQFRVRAENIAGASDPSRSTPLIMAADPVDPP 6043



 Score =  139 bits (336), Expect = 9e-31
 Identities = 127/464 (27%), Positives = 193/464 (41%), Gaps = 29/464 (6%)

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIMR- 1676
            + T  K +   +  L       + + A N  G S    +E ++   D  + P  P  +  
Sbjct: 5495 VDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYALTV 5554

Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
             E+S+  V ++W+PP  DGG  +TKY IEK E    RW+K          Y +  ++E  
Sbjct: 5555 VEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKSGKTSGPESKYRVTDVDEGT 5614

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID--NESVYITWFPSEK 1793
            E  F+V A+N  G      SEP VI T  D  S          +D   E + ITW   EK
Sbjct: 5615 EVQFQVRAENEAGVGHP--SEPTVIMTIEDAISPPSPPLEVKIVDASREHINITWKAPEK 5672

Query: 1794 NGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQK---LSINTTYQFRIYARNEIGTSL 1849
            NGGSPI  Y VE+ + E +KW           R +    +     Y  R+ A N IG S 
Sbjct: 5673 NGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSD 5732

Query: 1850 PYTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
            P    D +      + P+     ++ VV E     + +    P      P   +      
Sbjct: 5733 PSEISDGVFAKDPDSAPTIDVATQDIVVVEGEKMDIKI----PYRAIPKPSMVWKKGDTE 5788

Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
            +K +    +      VH   ++  K +D  ++ ++ EN++G    T S +V         
Sbjct: 5789 LKTEDRLTLTCELNRVHLELLK-CKHEDAGVYTVTLENSLGSVTGTVSVTVI---GLPGQ 5844

Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
                +P E+     N    SW  PE DGG+P+L Y +  R+  K  ++ V   + N L F
Sbjct: 5845 CKDISPSELT---KNSCKISWEPPENDGGSPILHYVLERREAQKKTFLPVMSGE-NVLSF 5900

Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070
             ++DL  N  Y  R+ A N+IG  E LE   P  +I  +  H D
Sbjct: 5901 VVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPV-IIEEQKQHPD 5943



 Score =  138 bits (333), Expect = 2e-30
 Identities = 195/934 (20%), Positives = 359/934 (38%), Gaps = 76/934 (8%)

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNF 883
            T     PP+F  +   +       +K    +   P  +  W++    I  S+   I    
Sbjct: 217  TRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRIISRQ 276

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
               ++EL     D   DSG+Y C ASN  G  +  A++ I   E   F++ L  +     
Sbjct: 277  TTSSLELPSPTKD---DSGEYSCRASNKHGSDTCSAQLNITASEPARFLRKL-SNISIPM 332

Query: 943  GKTVILECQTS--HTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
             + + LEC+ +    +   WY + K++ +   +   + +                G+  C
Sbjct: 333  SQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGIYSC 392

Query: 1000 IVKD---QETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054
             V +   +E     V   T P  F++KL D  +       LE     +    V W +DG+
Sbjct: 393  EVSNAFGREICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKDGK 452

Query: 1055 IIKPKKNKYDFEKRGHIRKL-YIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEI 1109
             +     +Y+ +   +   L  +   +    G YSC    I   + C A+V  V  P   
Sbjct: 453  QLY-ASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTEPARF 511

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK-IYD 1167
            + +L +  +    K   E   T    + V W+KDG ++  S      + G    L+ +++
Sbjct: 512  VKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCILECLHE 571

Query: 1168 CDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
            C+    G+YSCEV NS     C A +T       F L+L +  +  +             
Sbjct: 572  CNDATPGKYSCEVSNSIGTDICHANITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAP 631

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTL-IIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             + VTWYK    +  + ++         TL  + +CT++   +Y+C + ++        E
Sbjct: 632  KIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSYGKDICHAE 691

Query: 1283 VVEF--PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V  F  P + V    +  +++G  + L   ++   +    W  + K           +  
Sbjct: 692  VTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASYRCNTKVIG 751

Query: 1341 KSASLT-IKKVENTDAGIYKLRLENNCG----HADVEMNVTILDKPSPPGKPNILEIDSS 1395
             +  L  + + +    G Y   + N  G    HA V +       P+   KP+   I+ +
Sbjct: 752  NTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKPS-EHIEDA 810

Query: 1396 SINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
               +   E   +G+  + + +  + +EI+T++   V    K+  ++  L+  +      Y
Sbjct: 811  EGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVS--FKSNVAVMCLRKATVTDSGVY 868

Query: 1455 AVNEVDISDASETTEYYKVIKET-KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
              +    S+ + T  +  V+  T + + PT + PLK +T    E + L+C   G P  K+
Sbjct: 869  TCS---ASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKI 925

Query: 1514 TWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
             W +D +++ ++ +T     +                 Y C A N+ G   +   V I+ 
Sbjct: 926  QWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTIKD 985

Query: 1570 K--------------PVIT--ISN----EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWY 1607
            K              P  T  + N    E+ K  H V  G    + A + G P P V W 
Sbjct: 986  KAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFI-AKVGGDPIPNVKWM 1044

Query: 1608 K-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            K    ++ +    NI  K + S + IKE+ +S S +Y   ASN  G       L V +K 
Sbjct: 1045 KGKWRQMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEK- 1103

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
             K  GP +   +  +    + K P +D  +++ +
Sbjct: 1104 -KESGPEV---VKLKKTPSKQKSPKEDKDIDIVE 1133



 Score =  138 bits (333), Expect = 2e-30
 Identities = 97/364 (26%), Positives = 160/364 (43%), Gaps = 18/364 (4%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLK---VYDKPSKPEGPVIMREI--SRESVTI 1685
            R++EL      ++ + A N  GT    V  K     D    P  PV+   +  +++SV++
Sbjct: 8310 RVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDPIVLPSPPVLPEAVDKTKDSVSL 8369

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIA 1743
             W+ P  DG  ++  Y IE  +P    W+K  +         + +  L E  E+ FR++A
Sbjct: 8370 SWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMA 8429

Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
             N  G SE A   EP+ +   LD P           I +ES Y+TW   E +GG+ I  Y
Sbjct: 8430 VNAAGKSEPAYVKEPVKVHDRLDKPGPPRNLAISE-ITSESAYLTWQKPEDDGGAVISHY 8488

Query: 1803 KVEIKQ-EGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             V+ K    + W          + + Q L   T Y FR+ A N+ G S    ++  I   
Sbjct: 8489 IVQKKDVAAENWVPVCAASKKLSLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAV 8548

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
              L PP  P+N    ++    V L+W  P+  GGS IT +I+E +      W    TV  
Sbjct: 8549 DPLYPPGPPKNLHHVDADKTEVWLQWEWPDRTGGSEITGFIVEHQEEGATDWVTFKTVS- 8607

Query: 1921 SVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
              +  C +  + E     FR+ ++N +G+S P  S  +  ++       PT  ++++++ 
Sbjct: 8608 --NPQCHVTGLVEGKTYRFRVKSQNAIGISRPDTSVPITCQEKTLA---PTIEVDVKLIE 8662

Query: 1980 SNIV 1983
              +V
Sbjct: 8663 GLVV 8666



 Score =  134 bits (323), Expect = 3e-29
 Identities = 163/681 (23%), Positives = 266/681 (39%), Gaps = 61/681 (8%)

Query: 1418  EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             E +E    EW     +     SI  LK    YRFR  A N +  S  +ET E Y+ IKE 
Sbjct: 9932  EEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYE-IKEQ 9990

Query: 1478  KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533
               +   +   L  +T +    + +  +  G P P   W R    +    + A    +N  
Sbjct: 9991  MFEPKIIMTEL--VTAKAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMC 10048

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-----KPVITISNEDIKQKHKVGD 1588
                           Y  +A N  G++E +  + I+      +P   IS+ D         
Sbjct: 10049 VLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDIPGPPEPPFEISDID---SDACTL 10105

Query: 1589  EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
              W       G      +  +  +    D    +++  K    RI +L       + + A 
Sbjct: 10106 SWNKPTEDGGSNITNYV-VEKCDVSRGDWVTALSSCGKAG-CRIGKLIPGKEYIFRVRAE 10163

Query: 1649  NTAGTS----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
             N  G S    S  +  K  +D P +P    I  +++++ + + W  P  DGG  +T Y I
Sbjct: 10164 NRFGISDPLASERMVAKFPFDVPGEPLNCRI-NKVNKDCMFVAWDKPESDGGSPVTGYYI 10222

Query: 1704  EKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761
             E+ E ++  W+K  D V R  E  C   L E  EY FRV A N  G  + + +++ I  +
Sbjct: 10223 ERKERNSLLWVKANDSVVRTTEYPC-AGLIEGLEYTFRVSAINRAGQGKPSKKTDFITAR 10281

Query: 1762  TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXX 1820
             T +D P           +   +V + W   + +GGS II Y VE ++  G  W       
Sbjct: 10282 TPVDAPG----KPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSS 10337

Query: 1821  XXXARIQ----KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                 R +     L     YQFR+ A+  +  S P    D I +     PP          
Sbjct: 10338 QNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILVSAENVPP---------- 10387

Query: 1877  STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE---- 1932
                 SV +K   P   G        +  K +   +W+K      +  E  +   +     
Sbjct: 10388 RIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFSL 10447

Query: 1933  KDEIIFRISAENTVGVSLPTESQSVRLE---KHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
               + + ++ A N  G+     S +   E   K   +P PP A +++  + S+ V  SW  
Sbjct: 10448 SLDAVTKLHAGN-YGIHAANASGNTTAEIQLKILDIPGPP-ASVKLDEILSDRVKLSWEA 10505

Query: 1990  PEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             P  DGG+P+  Y +  R+ ++  W +V  K+  +T + ++  L E H Y  R+ A N  G
Sbjct: 10506 PLVDGGSPITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYG 10565

Query: 2049  -----LSEPLESDEPFKVIPG 2064
                  +SEP+ +  PF  +PG
Sbjct: 10566 TGDAIISEPVVARNPF-TVPG 10585



 Score =  125 bits (301), Expect = 2e-26
 Identities = 114/476 (23%), Positives = 193/476 (40%), Gaps = 15/476 (3%)

Query: 1592  VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
             V  V++  P P     +   K E  +E+   T  K   I I  LK     ++ + A N+ 
Sbjct: 9914  VEPVVQPPPEPVAAEEEKEEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSM 9973

Query: 1652  GTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
             G+S    T + Y+ K    E  +IM E+       + +      G        ++ E + 
Sbjct: 9974  GSSLPTETREAYEIKEQMFEPKIIMTELVTAKAGAKLRVEALVSGKPAPACQWKRGENNV 10033

Query: 1711  NRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
                 ++A    +++    I+ ++      + ++A+N  G  E  ++  I+I+   D+P  
Sbjct: 10034 VSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIE--QTLKIIIR---DIPGP 10088

Query: 1770  XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXX-XXXXARIQ 1827
                      ID+++  ++W    ++GGS I +Y VE     +  W            RI 
Sbjct: 10089 PEPPFEISDIDSDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWVTALSSCGKAGCRIG 10148

Query: 1828  KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
             KL     Y FR+ A N  G S P  S+ ++        P +P N  +++     + + W 
Sbjct: 10149 KLIPGKEYIFRVRAENRFGISDPLASE-RMVAKFPFDVPGEPLNCRINKVNKDCMFVAWD 10207

Query: 1888  EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
             +PES+GGSP+T Y IE K      W K         E+    + E  E  FR+SA N  G
Sbjct: 10208 KPESDGGSPVTGYYIERKERNSLLWVKANDSVVRTTEYPCAGLIEGLEYTFRVSAINRAG 10267

Query: 1948  VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
                P++       +  T    P  P E+  V  N V   W  P+ DGG+ ++GY +    
Sbjct: 10268 QGKPSKKTDFITAR--TPVDAPGKP-EVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMR 10324

Query: 2008  VTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +    W+       N  +  +    L E   Y  R+ A+  + +S P E  +P  V
Sbjct: 10325 LPGDTWVRCNTSSQNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILV 10380



 Score =  121 bits (291), Expect = 3e-25
 Identities = 99/402 (24%), Positives = 169/402 (42%), Gaps = 15/402 (3%)

Query: 1302  GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
             GS + L    +  P P   W   +  IK  +            + ++KV   DAG Y L 
Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863

Query: 1362  LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
             L++  G     + V +LD P PP    I E    S +I WDEP   G S I  Y+V+ ++
Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPLNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRD 10923

Query: 1422  IDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
              +   W +V  + TKT   I++L+   SY FR  A N+  I +  ET +    ++ ++  
Sbjct: 10924 AERKAWSNVTTSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVD---AVRASEQP 10980

Query: 1481  SPTVEKPLKNITTEPNEDIELTCIFGGVPQ--PKVTWYRDGKKLKTAKATYENRXXXXXX 1538
              P ++     +T +         I  G  +    V    +G+  K  +            
Sbjct: 10981 GPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGED-KWKELLRSKNMQYSAK 11039

Query: 1539  XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK------HKVGDEWLV 1592
                      Y+  A ND G+      + +  K +  + + D++         K G    +
Sbjct: 11040 DLVEGREYKYRVFATNDSGDGPVK-ELSVLAKDINVLPSCDLRDLPNLNYIAKEGSNVRL 11098

Query: 1593  TAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
                I G P P V W K  ++ L +     + +    + + I++ +R+ +SKYTI   N+A
Sbjct: 11099 KIPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKYTITLRNSA 11158

Query: 1652  GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             GT    + ++V  KP  P GP+  +E++ +  T++W  P DD
Sbjct: 11159 GTKESTIFVRVVGKPGIPNGPIKFKEVTADGATLKWSAPKDD 11200



 Score =  120 bits (290), Expect = 3e-25
 Identities = 81/300 (27%), Positives = 133/300 (44%), Gaps = 9/300 (3%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW---KXXXXX 1819
             LD+P           + ++ V ++W     +GGSPI +Y V+ ++  + +W         
Sbjct: 10480 LDIPGPPASVKLDEIL-SDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQVSAKISR 10538

Query: 1820  XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                   +++L     YQFR+ A N  GT     S+  +      T P      V++  T 
Sbjct: 10539 DTTECSVERLIEGHEYQFRVRAENHYGTGDAIISEP-VVARNPFTVPGACDPPVLTNITK 10597

Query: 1880  RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
               +T+ W EP  +G SPI  Y++E +  K  +WTKI           +  + E  +  FR
Sbjct: 10598 EHMTVSWKEPSDDGKSPILGYLVEKRETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFR 10657

Query: 1940  ISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
             + A N  G+  P++ S +         P PP +P  I    S I +T W  P  DGG+ +
Sbjct: 10658 VIAVNKAGLGKPSDPSNAASALDPLYPPGPPISPKAIDTTNSTIKLT-WTKPANDGGSDI 10716

Query: 1999  LGYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             LGY +  + +  T W+      ++    + +  L EN  Y +R+ A N+IG S+P E  E
Sbjct: 10717 LGYLVECKRINTTDWIRCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPE 10776



 Score =  119 bits (287), Expect = 8e-25
 Identities = 88/286 (30%), Positives = 132/286 (46%), Gaps = 14/286 (4%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---W-KXXXXXXXXXARIQKLSINTT 1834
            I  ES Y+TW   E NGGS + +Y VE +   KK   W +           + KL    T
Sbjct: 6876 IKAESCYLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWDQLTCCIMDRRYGVYKLEAYGT 6935

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            YQF+I A N+ G S    S+ K+ +      P  P+   +   T  S+ + W  P+ NGG
Sbjct: 6936 YQFQIKAENKYGISDGCESE-KVVLKDPFGLPGPPQRPRIISHTRSSMVVTWEPPKDNGG 6994

Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS 1949
            S I  Y +E +      W+++    VT       E+ + ++ E  E  FR+ A+N  GV 
Sbjct: 6995 STIQGYWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVG 7054

Query: 1950 LPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
             P+E+ + V        PS P AP+      S++ + SW  P+ DGG+P+ GY + ++D 
Sbjct: 7055 PPSEATECVFALDPRNPPSQPPAPVVTDKSPSSVSL-SWTPPDRDGGSPIKGYIVEVQDE 7113

Query: 2009 TKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                W  +   D  + T  + +  L EN     RI A N  G SEP
Sbjct: 7114 GSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEP 7159



 Score =  118 bits (285), Expect = 1e-24
 Identities = 87/292 (29%), Positives = 134/292 (45%), Gaps = 18/292 (6%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXAR-IQKLSINTT 1834
            I N SV  TW     +GGS II+Y +E K        W             + KL     
Sbjct: 6180 IRNTSVVCTWDAPLDDGGSEIINYILEKKDNTSDDIGWVTVTSTHKGYNYPVTKLIEGKE 6239

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y FR+ A N+ G   P  S+  +   +   PP  P    + E TS +V L W EP+ NG 
Sbjct: 6240 YIFRVTAENKFGCGHPCYSEPLVAKNQ-FEPPDAPNVPRIGEVTSSTVALSWHEPKDNG- 6297

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG---VSLP 1951
            SPI  Y +E + V  K W ++ +   S     +E + E    +FR+ AEN  G    S+P
Sbjct: 6298 SPILGYWVERREVNSKYWIRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGEFSVP 6357

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
            T+ Q+        +P  P  P  + +  + I + SW  P ++GG  +LGY++    V + 
Sbjct: 6358 TDPQAAM---DPILPPGPPVPKIVDVTNTTIDI-SWQPPLYNGGGEILGYHVERCLVGEK 6413

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE-----IGLSEPLESDEP 2058
             W+   +      K+ +  L+E   Y +R+YA NE      G++EP+++ EP
Sbjct: 6414 DWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEP 6465



 Score =  117 bits (282), Expect = 3e-24
 Identities = 67/228 (29%), Positives = 113/228 (49%), Gaps = 9/228 (3%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            +++I  +N+ GT   + + D I +      P   +N  V ++    V+L W EPES+GGS
Sbjct: 4429 RYKIVIKNKHGTGEAFINLDVIDV------PGPVKNLHVVDTADGEVSLAWEEPESDGGS 4482

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTES 1954
             I  Y++E + VK K+WT + T    + E+C+  +   +   FR+ A N VG     T  
Sbjct: 4483 KILAYVVERRDVKRKTWT-MATDRADIPEYCVGGLHRDNMYFFRVCARNRVGNGETVTTD 4541

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
            ++V+ +    VP  P   + + +V       SW  P +DGG+ +  Y I +RD T   W 
Sbjct: 4542 EAVQAKNKFDVPDAPQKFM-VGVVNRFGATVSWEPPLFDGGSEVTSYIIELRDRTSVKWE 4600

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
                V    L   + D+ EN  Y+ R+ A N+ G+ +P  + +P K++
Sbjct: 4601 PAMVVKAEDLTATLSDVVENKEYIFRVRAENKAGIGQPSAATDPVKIM 4648



 Score =  116 bits (279), Expect = 7e-24
 Identities = 69/260 (26%), Positives = 120/260 (46%), Gaps = 5/260 (1%)

Query: 1587  GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
             G +  + A I+G P P V W K    +++ +   I T +  +++ ++++ R  + KY + 
Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863

Query: 1647  ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
               + +G     V +KV D P  P   ++++E S++S +I W  PL DGG E+T Y ++K 
Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPLN-LMIKETSKDSASILWDEPLIDGGSEITGYIVDKR 10922

Query: 1707  EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
             + +   W  V        ++ I+ L     Y FRV+AQN  G  E  E+   V  +    
Sbjct: 10923 DAERKAWSNVT-TSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAVRASEQPG 10981

Query: 1767  PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826
             P           +  +S  ++W     +GGS II Y +E+     KWK            
Sbjct: 10982 P---VMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGEDKWKELLRSKNMQYSA 11038

Query: 1827  QKLSINTTYQFRIYARNEIG 1846
             + L     Y++R++A N+ G
Sbjct: 11039 KDLVEGREYKYRVFATNDSG 11058



 Score =  113 bits (271), Expect = 7e-23
 Identities = 153/694 (22%), Positives = 280/694 (40%), Gaps = 82/694 (11%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  F K    Q + +G  + LE     I +  + W   G++       +  +  +    C
Sbjct: 698  PARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASYRCNTKVIGNT---C 754

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751
             +  +    +   G Y+   +N +G      ++ + T  K PP   + P + +   +G+ 
Sbjct: 755  VLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKL 814

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            V L ++V G+   ++ W K+NK +    +   S     ++  L+   V D GVYT  A N
Sbjct: 815  VKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASN 874

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G A    V+ + E       PP F    + +TV E   + L   V  +P   I W ++
Sbjct: 875  EAGTASFQVVVNITE----QKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKD 930

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKV 928
               ++ S +    F      L I N  S+ D+GDY C A+N+AG      +VTI D   V
Sbjct: 931  RREVTSSASTKMTFVDGTATLEI-NQASKTDAGDYLCKATNNAGSEFSKTKVTIKDKAGV 989

Query: 929  T------------FVKHLQKSYETEEGKTV-ILECQTSHTVS---------TKWYHNK-K 965
                           K L   +  EE K++ I+E  T+  ++          KW   K +
Sbjct: 990  APAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKWMKGKWR 1049

Query: 966  EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV---KETIPE 1018
            +++      I Q+G+            D G  +C+  ++    E ST L V   KE+ PE
Sbjct: 1050 QMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKESGPE 1109

Query: 1019 FIR-----KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
             ++       Q    ++KD+ I+E+  N +  +  +E+   +      +   +    ++K
Sbjct: 1110 VVKLKKTPSKQKSPKEDKDIDIVELLRNVDPKE--YEKYARMYGITDFRGLLQAIEFLKK 1167

Query: 1074 LYIRNTSVHDEGE-YSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132
                 +   +E E  + ++ D     E +    P  ++  + +Q      +A FE E+  
Sbjct: 1168 EKGEESGRPEEDEDLAKLVSDLQRRMENSE---PVTLLKDITDQTTQLNKEAVFECEIKV 1224

Query: 1133 G--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
               +  + W+KD  +++ ++   + + G +Q LKI + D                     
Sbjct: 1225 NYPEITLAWYKDTQKLETNDKYDIKLVGDRQILKIKNSD--------------------- 1263

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
                 I FT R+   I+V     A    E+  +   VTWYK    ++++ K+T   + ++
Sbjct: 1264 ----QIQFTKRIQN-IVVNERQSATFECELSFDNAVVTWYKDAWELKESLKYTFKCEGRR 1318

Query: 1251 RTLIIRKCTEDDQCEYTCVL-LDAKSTTKLKVEV 1283
              +IIR  T DD+  Y+ +  L+    TK   E+
Sbjct: 1319 HFMIIRNVTADDEGVYSVIARLEPVGETKSTAEL 1352



 Score =  109 bits (263), Expect = 6e-22
 Identities = 67/207 (32%), Positives = 98/207 (47%), Gaps = 7/207 (3%)

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
            +DD  T+     PP Q     +S  T  S+T+ W EPES+GGSPIT Y +E K    K W
Sbjct: 7542 ADDSCTLLIQQVPPGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLERKETTSKRW 7601

Query: 1913 TKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPS 1967
            +++    V        H +  + E  + +FR+SA N  GV  P+E S+     +    PS
Sbjct: 7602 SRVTRDPVRPMPMGVSHRVTGLIEGSQYLFRVSAINAAGVGPPSEPSEPTFAREPIAPPS 7661

Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027
            PPT   ++           W  P  DGG+ ++GY +  ++     W++    +V   KF 
Sbjct: 7662 PPTP--KVTDWTKTTADLEWIPPLKDGGSKIIGYFVEYKEEGTEAWVKAKDKEVRGTKFV 7719

Query: 2028 IRDLSENHTYMIRIYARNEIGLSEPLE 2054
            I  L EN  +  R+ A N  GL EP E
Sbjct: 7720 ITGLKENALFKFRVIALNAAGLGEPGE 7746



 Score =  105 bits (252), Expect = 1e-20
 Identities = 185/990 (18%), Positives = 365/990 (36%), Gaps = 83/990 (8%)

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA--DILEGIPPTFSKKPKAQYVDEGSDI 651
            +T+ L + +P  D   E +             A  +I    P  F +K     +     +
Sbjct: 277  TTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITASEPARFLRKLSNISIPMSQKL 336

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
             LEC+     +  + W   G+++      +  +  +    C++  +        G Y+  
Sbjct: 337  RLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNS---CTLESLQECDNTTTGIYSCE 393

Query: 712  AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
              N  G     I     T   EP + ++ L  M +   + + L     G P+  +TW K+
Sbjct: 394  VSNAFGRE---ICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKD 450

Query: 772  NKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-VITVEEPTE 827
             K + A     TK   ++  +  L     +  G Y+ +  N  G  +  A V+ V EP  
Sbjct: 451  GKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTEPAR 510

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
                   F+ +  ++ +     ++L    T  P   +TWY++ + +  S        G+ 
Sbjct: 511  -------FVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDT 563

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
              L   +  ++   G Y C  SNS G     A +T   E   F   L K  +    K + 
Sbjct: 564  CILECLHECNDATPGKYSCEVSNSIGTDICHANITTFTEPARFELKL-KDKQVAMSKNLK 622

Query: 948  LECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQ 1004
            LEC  +    +   WY + K++           G             +  G   C V + 
Sbjct: 623  LECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNS 682

Query: 1005 ETSTMLVVKETI----PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPK 1059
                +   + T       F++ L D  +++     LE          V W +DG+     
Sbjct: 683  YGKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAY-A 741

Query: 1060 KNKYDFEKRGHIRKL-YIRNTSVHDEGEYSCILRDES----CTAEVTV---VELPPEIIT 1111
              + + +  G+   L Y+     +  G+YSC + +E     C A VT+    ++PP   T
Sbjct: 742  SYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPP-TFT 800

Query: 1112 RLQNQKVN--KGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            +  ++ +   +G     E  ++    L V W+KD  EI  S+   ++       + +   
Sbjct: 801  KKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKA 860

Query: 1169 DLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI-PD 1222
             + D+G Y+C   N   TA    ++ + E     T  +P + + V       L+  +   
Sbjct: 861  TVTDSGVYTCSASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGS 920

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--------AK 1274
              + + W K +  +  +    +       TL I + ++ D  +Y C   +         K
Sbjct: 921  PPVKIQWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTK 980

Query: 1275 STTKLKVEVV-----------EFPPKI-----VDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
             T K K  V            +   K+     ++  +   I      T +      P PN
Sbjct: 981  VTIKDKAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPN 1040

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
             +W +  K  +     + +I  K   + L IK+V  +D+G Y+    N   H ++E +  
Sbjct: 1041 VKW-MKGKWRQMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNK--HGEIECSTD 1097

Query: 1377 I-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
            + +D+    G P ++++  +        P+   +  I+  +      +  ++  +  IT 
Sbjct: 1098 LNVDEKKESG-PEVVKLKKTPSK--QKSPKEDKDIDIVELLRNVDPKEYEKYARMYGITD 1154

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
             +  +Q ++     +       E D   A   ++  + ++ +  +  T+ K + + TT+ 
Sbjct: 1155 FRGLLQAIEFLKKEKGEESGRPEEDEDLAKLVSDLQRRMENS--EPVTLLKDITDQTTQL 1212

Query: 1496 NEDIELTC-IFGGVPQPKVTWYRDGKKLKT 1524
            N++    C I    P+  + WY+D +KL+T
Sbjct: 1213 NKEAVFECEIKVNYPEITLAWYKDTQKLET 1242



 Score =  103 bits (246), Expect = 7e-20
 Identities = 95/382 (24%), Positives = 169/382 (44%), Gaps = 22/382 (5%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437
             P PP  P  ++  +S+I + W +P N G S I+ Y+VE + I+TT+WI     KN+  T 
Sbjct: 10685 PGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVECKRINTTDWIRCNVPKNLQDTN 10744

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKN-ITTEP 1495
               +  L  NS Y+ R  AVN++  S   E  E + + K+  +     ++  LK+ +    
Sbjct: 10745 YVVTGLLENSEYQLRVSAVNKIGFSQPCEVPEKH-IAKDVFVTPEAELDAELKDTLVLTA 10803

Query: 1496  NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCI 1551
                ++L     G P P+VTW +    +K  +     T +                 Y   
Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNG 1610
               +  G    + +V +   P   + N  IK+  K     L    +I+G    E+  Y   
Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPL-NLMIKETSKDSASILWDEPLIDG--GSEITGYIVD 10920

Query: 1611  NKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              +    K + N+TT    +  +I++L+   S  + + A N  G      T+    + S+ 
Sbjct: 10921 KRDAERKAWSNVTTSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAV-RASEQ 10979

Query: 1670  EGPVIMRE---ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
              GPV+  +   ++++S T+ WK P+ DGG  +  Y +E    + ++W ++    ++++ Y
Sbjct: 10980 PGPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGE-DKWKELLR-SKNMQ-Y 11036

Query: 1727  CIQKLNENCEYMFRVIAQNPVG 1748
               + L E  EY +RV A N  G
Sbjct: 11037 SAKDLVEGREYKYRVFATNDSG 11058



 Score =  100 bits (240), Expect = 4e-19
 Identities = 120/523 (22%), Positives = 204/523 (39%), Gaps = 29/523 (5%)

Query: 1554 NDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            N HG    SC V +  KP   +    ++I+    V   W       G      I  K  N
Sbjct: 6152 NAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCT-WDAPLDDGGSEIINYILEKKDN 6210

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKP 1666
              ++     +T+  K     + +L       + + A N  G      S   V    ++ P
Sbjct: 6211 TSDDIGWVTVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHPCYSEPLVAKNQFEPP 6270

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
              P  P I  E++  +V + W  P D+G   +  Y +E+ E ++  WI+V          
Sbjct: 6271 DAPNVPRI-GEVTSSTVALSWHEPKDNGS-PILGYWVERREVNSKYWIRVNSNLLSALNV 6328

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNESVY 1785
             ++ L E   Y+FRV A+N  G  E   S P   + A+D +            + N ++ 
Sbjct: 6329 KVEGLMEGLVYVFRVCAENLAGPGEF--SVPTDPQAAMDPILPPGPPVPKIVDVTNTTID 6386

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYAR 1842
            I+W P   NGG  I+ Y VE    G+K W           +  +  L+    Y  R+YA 
Sbjct: 6387 ISWQPPLYNGGGEILGYHVERCLVGEKDWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAV 6446

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
            NE G   P  ++  +   +    P    +  V              P    G P+    +
Sbjct: 6447 NEGGHGAPGMTEP-VQAKEPEEAPGVEFDISVRNGVIIRAGETLRLPAVVTGRPVPE--V 6503

Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
            ++     +   + V +   +      I+     D  I++I+  N  G    T+S SV+++
Sbjct: 6504 KWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPSG----TKSVSVKVD 6559

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
                VP P    L+   V   ++  +W  P  +GG+ ++GY +  +D    ++ +   ++
Sbjct: 6560 V-MDVPGP-VVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVERKDAKMHIYRQ--PLE 6615

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            V   K +I  L +   YM R+ ARN+ GL  P+E      V P
Sbjct: 6616 VAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDP 6658



 Score =   99 bits (238), Expect = 7e-19
 Identities = 132/594 (22%), Positives = 228/594 (38%), Gaps = 32/594 (5%)

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVR 1138
            S+H E +++  L  E+        E+PP    ++ N + N GN   FE E+ +  +   +
Sbjct: 199  SIHVEEKHT--LTGETSQGFTRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFK 256

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEP 1194
            WFK GSEI+ S+ +++        L++     DD+GEYSC      G+  C+A L +   
Sbjct: 257  WFKAGSEIKQSDKVRIISRQTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITAS 316

Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF-TLISDVKKRT 1252
                 LR    I +P +    L  +   D  L VTWYK    +  + ++ T ++D     
Sbjct: 317  EPARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTL 376

Query: 1253 LIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
              +++C       Y+C + +A  +      V  V  P + V    +  I     + L   
Sbjct: 377  ESLQECDNTTTGIYSCEVSNAFGREICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECT 436

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKLRLENNCGHA 1369
            +   P+    W  + K +         + S S  L  + +  N   G Y   + N  G  
Sbjct: 437  FTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTD 496

Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
                 V  + +P+   K  + ++          E   TG   I  +V  Y++     + S
Sbjct: 497  KCHAQVVAVTEPARFVK-KLTDVAIPVTQKLRLECTFTGAPKI--FVTWYKD-GKQLYAS 552

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
             +  TK       L+               ++S++  T   +  I  T  +    E  LK
Sbjct: 553  YRYNTKVIGDTCILECLHECNDATPGKYSCEVSNSIGTDICHANI-TTFTEPARFELKLK 611

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX------XXX 1543
            +     +++++L C F G P+  VTWY+DGK+L  A   Y                    
Sbjct: 612  DKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQL-YASYRYNTTVVGNTCTLECLHECTKE 670

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP---VITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                Y C   N +G+      V     P   V T++++ ++Q    G +  + A  +GI 
Sbjct: 671  TPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQQ----GQKLRLEASFKGIG 726

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIR-IKELKRSHSSKYTIEASNTAGT 1653
               V WYK+G +       N      T V+  + E   +   KY+ E  N  G+
Sbjct: 727  KIFVTWYKDGKQAYASYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGS 780



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 74/291 (25%), Positives = 120/291 (41%), Gaps = 19/291 (6%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK--PSKPEGPVIMREI---SRESVTIE 1686
            +  L  +H  ++ ++A N  G        + +    P +P GPV   ++   S+ S+T+ 
Sbjct: 9602 VTSLLPNHEYQFRVKAENEIGVGDASKPSRTFTARDPVEPPGPVSNLKVTDSSKTSITLA 9661

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNR-----WIKVADVDRDVET-YCIQKLNENCEYMFR 1740
            W  P  DGG  L  Y +E       +     W +     + + T + +  L+E  EY FR
Sbjct: 9662 WTKPTYDGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFR 9721

Query: 1741 VIAQNPVGFS-----EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            V   +   +S      A E    V    LD P           +   S  +TW P E +G
Sbjct: 9722 VTRDDSGKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTD-MTMSSCNLTWSPPETDG 9780

Query: 1796 GSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
            GS +  Y VE ++ + K W            +I  L   T Y FR+ A NE G  +P  +
Sbjct: 9781 GSNVTHYIVEKREIDRKTWATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVT 9840

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
                     ++ P  P+   V E +  S T+ W +P  +GG+ I  Y+I++
Sbjct: 9841 PKSYLASDPVSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVIDY 9891



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 53/191 (27%), Positives = 96/191 (50%), Gaps = 9/191 (4%)

Query: 1859  IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
             I K L  P  P N ++ E++  S ++ W EP  +GGS IT YI++ +  + K+W+  VT 
Sbjct: 10876 IVKVLDTPGPPLNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSN-VTT 10934

Query: 1919  GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRM 1977
               +     IE+++      FR+ A+N  G+  P E+  +VR    A+    P    +  +
Sbjct: 10935 SCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAVR----ASEQPGPVMDFKTLL 10990

Query: 1978  VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
             V  +    SW  P  DGG+ ++ Y + + +  +  W E+  +    ++++ +DL E   Y
Sbjct: 10991 VTKDSCTLSWKKPISDGGSRIIAYVLEVLN-GEDKWKEL--LRSKNMQYSAKDLVEGREY 11047

Query: 2038  MIRIYARNEIG 2048
               R++A N+ G
Sbjct: 11048 KYRVFATNDSG 11058



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 5/170 (2%)

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGI 1357
            + G+ + L  D    P+P  +W     ++K     + +ID+K   ++L+I     +D   
Sbjct: 5065 RAGTKIDLPADVLGKPEPRVKWTKADLVLKP--EERITIDTKPGHSTLSIANTTRSDTAT 5122

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            Y +   N  G A   ++V ILDKP PP   +I EI + S  + W+ P + G S +  Y+V
Sbjct: 5123 YIIEAVNTSGRATATVDVNILDKPGPPAAFDISEITNESCCLAWNAPRDDGGSPVANYIV 5182

Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            E +  D  EW  +   I +T      L     Y FR  A N+  I   +E
Sbjct: 5183 EMRPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYGIGTPAE 5232



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 52/180 (28%), Positives = 75/180 (41%), Gaps = 3/180 (1%)

Query: 1286  FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
             F PKI+  E     K G+ + +       P P  +W      +                L
Sbjct: 9992  FEPKIIMTEL-VTAKAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVL 10050

Query: 1346  TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
              IK V   D+G Y L  EN+ G  +  + + I D P PP  P  I +IDS +  + W++P
Sbjct: 10051 IIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDIPGPPEPPFEISDIDSDACTLSWNKP 10110

Query: 1405  ENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
                G S I  YVVE  ++   +W+ ++ +  K    I  L     Y FR  A N   ISD
Sbjct: 10111 TEDGGSNITNYVVEKCDVSRGDWVTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISD 10170



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 91/450 (20%), Positives = 177/450 (39%), Gaps = 26/450 (5%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            EQ   P F   L+P    +G  +   C V G P  +I W +    +  S   +M +  D 
Sbjct: 889  EQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTF-VDG 947

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
             ATL I +    DAG + C A N AG   S T++ ++       + +             
Sbjct: 948  TATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTIK-----DKAGVAPAAAPAAPTTPQ 1002

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVA 683
                L+ +   F ++PK+ ++ E        ++   P P++ W+  K  ++     I++ 
Sbjct: 1003 ATKKLDNL--FFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRINIQ 1060

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
             +       S L+I  V K   G Y  VA N+ GE      L +   ++  P+V++  K+
Sbjct: 1061 QKGQE----SKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKESGPEVVKLKKT 1116

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGV 802
               ++         +V   R  +   +  K  +    T   G   +I  LK +K ++ G 
Sbjct: 1117 PSKQKSPKEDKDIDIVELLR-NVDPKEYEKYARMYGITDFRGLLQAIEFLKKEKGEESG- 1174

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PV 861
               + E  E +A+   +++  +   EN+EP   +    + T +          +  N P 
Sbjct: 1175 ---RPEEDEDLAK---LVSDLQRRMENSEPVTLLKDITDQTTQLNKEAVFECEIKVNYPE 1228

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             ++ WY++ + +  ++       G+   L I N D    +   + +  N    ++    +
Sbjct: 1229 ITLAWYKDTQKLETNDKYDIKLVGDRQILKIKNSDQIQFTKRIQNIVVNERQSATFECEL 1288

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
            + D   VT+ K    ++E +E      +C+
Sbjct: 1289 SFDNAVVTWYK---DAWELKESLKYTFKCE 1315



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 21/271 (7%)

Query: 1803  KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
             K E +++ ++W            I  L     Y+FR+ ARN +G+SLP  + +   I + 
Sbjct: 9931  KEEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYEIKEQ 9990

Query: 1863  LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
             +  P      +++E  +     K        G P      ++K  +    +         
Sbjct: 9991  MFEP----KIIMTELVTAKAGAKLRVEALVSGKPAP--ACQWKRGENNVVSSSRLAVHKS 10044

Query: 1923  HEHC---IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
                C   I+++  +D   + + AEN+ G    T    +R      +P PP  P EI  + 
Sbjct: 10045 QNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIR-----DIPGPPEPPFEISDID 10099

Query: 1980  SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
             S+    SW  P  DGG+ +  Y +   DV++  W+             I  L     Y+ 
Sbjct: 10100 SDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWV-TALSSCGKAGCRIGKLIPGKEYIF 10158

Query: 2040  RIYARNEIGLSEPLESDE-----PFKVIPGE 2065
             R+ A N  G+S+PL S+      PF V PGE
Sbjct: 10159 RVRAENRFGISDPLASERMVAKFPFDV-PGE 10188



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 68/315 (21%), Positives = 129/315 (40%), Gaps = 17/315 (5%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284
            + W K  + ++  ++ TL  ++ +  L + KC  +D   YT  L ++    T  + V V+
Sbjct: 5780 MVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTGTVSVTVI 5839

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343
              P +  D       K    ++          P   +++  +  +K K   P +  ++  
Sbjct: 5840 GLPGQCKDISPSELTKNSCKISWEPPENDGGSPILHYVLERREAQK-KTFLPVMSGENVL 5898

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEM-NVTILDK----PSPPGKPNILEIDSSSI 1397
            S  +K +       ++++  N  G  + +E+ N  I+++    P PP +   L   S+SI
Sbjct: 5899 SFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSI 5958

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITK-TQTSIQNLKTNSSYRFRAYA 1455
             + W  P   G   I  Y++E  E D   +   V N+      ++  L     Y+FR  A
Sbjct: 5959 TVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRA 6018

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPK 1512
             N    SD S +T    ++    +  P V    +    ++ +  E+I L     G P P 
Sbjct: 6019 ENIAGASDPSRSTPL--IMAADPVDPPQVTLFARIASGLSIKKGEEIRLDAYISGSPYPT 6076

Query: 1513 VTWYRDGKKLKTAKA 1527
            VTW R+ + ++   A
Sbjct: 6077 VTWLRNDENVRQPPA 6091



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 46/210 (21%), Positives = 92/210 (43%), Gaps = 16/210 (7%)

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT---- 1376
            + +  K ++    TK +    + SL +  +      ++++R EN  G+      +     
Sbjct: 7313 YFIEKKTVEGKAWTKVNPACTTQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKA 7372

Query: 1377 --ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT-----EW-- 1427
               +  P PP +  I+++    + + W  P+N G + + +Y +E    D++      W  
Sbjct: 7373 RDPIHPPDPPTRVKIIDVSKGIVTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQ 7432

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
             + ++I  T   +++L   + Y FR  AVNEV  S  S T     +I + + ++P +E P
Sbjct: 7433 CNRRDIDTTTFKVEDLHEGAEYEFRVKAVNEVGASRPSSTAG--PIIVKDQNRAPFIELP 7490

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
             + +  E   D  +     G P P +TW +
Sbjct: 7491 -EFMEIEQGTDAHIVAKIKGCPFPTLTWQK 7519



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 37/175 (21%), Positives = 67/175 (38%), Gaps = 1/175 (0%)

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
            V    +P P  +W    K +                L +      D G Y L+LEN+   
Sbjct: 4778 VPITGYPVPKPKWTFGDKELTAGDRVSMVTKPTYTELVVAPSVRPDKGTYTLQLENDVTS 4837

Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
               E+ V ++  PS P    + E+    +++ W+ PE+ G S +  Y VE +E+    W+
Sbjct: 4838 VSGEIEVNVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVEKREVSRKTWV 4897

Query: 1429 SV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
             V   +   + ++ ++     Y F   A N+    + +   E   V     +  P
Sbjct: 4898 KVISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDP 4952



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 68/325 (20%), Positives = 135/325 (41%), Gaps = 23/325 (7%)

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252
             P I  ++++ + + V A +D  L  E+  + +  VTW K    ++  ++F +       +
Sbjct: 10387 PRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFS 10446

Query: 1253  LIIRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYER--EYRIKRGSDVT 1306
             L +   T+     Y     +A   T    +LK+  +  PP  V  +     R+K   +  
Sbjct: 10447 LSLDAVTKLHAGNYGIHAANASGNTTAEIQLKILDIPGPPASVKLDEILSDRVKLSWEAP 10506

Query: 1307  LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAGIYKLRLEN 1364
             L VD  +   P   ++V+ +   + +  + S  I   +   +++++       +++R EN
Sbjct: 10507 L-VDGGS---PITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAEN 10562

Query: 1365  NCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
             + G  D  ++  ++ +     P     P +  I    + + W EP + G S I+ Y+VE 
Sbjct: 10563 HYGTGDAIISEPVVARNPFTVPGACDPPVLTNITKEHMTVSWKEPSDDGKSPILGYLVEK 10622

Query: 1420  QEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +E     W  I+ K + +    +  L   + Y FR  AVN+  +   S+ +     +   
Sbjct: 10623 RETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFRVIAVNKAGLGKPSDPSNAASALDPL 10682

Query: 1478  KIQSPTVEKPLKNITTEPNEDIELT 1502
                 P +    K I T  N  I+LT
Sbjct: 10683 YPPGPPISP--KAIDT-TNSTIKLT 10704



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 63/256 (24%), Positives = 108/256 (42%), Gaps = 18/256 (7%)

Query: 1714  IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
             IK  D D  V   C++K+N      + +   +  G    ++   +++K  LD P      
Sbjct: 10838 IKTTDTDTLV---CVEKVNRYDAGKYILNLDSVSG----MKMYTVIVKV-LDTPGPPLNL 10889

Query: 1774  XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSI 1831
                     +S  I W     +GGS I  Y V+ +  E K W          + +I+ L  
Sbjct: 10890 MIKET-SKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVTTSCTKTSFKIEDLEP 10948

Query: 1832  NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
               +Y FR+ A+N+ G   P  + D +   +   P    +  +V   T  S TL W +P S
Sbjct: 10949 GRSYCFRVLAQNQYGIGEPCETVDAVRASEQPGPVMDFKTLLV---TKDSCTLSWKKPIS 11005

Query: 1892  NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
             +GGS I  Y++E    + K W +++       ++  +++ E  E  +R+ A N  G   P
Sbjct: 11006 DGGSRIIAYVLEVLNGEDK-WKELLR--SKNMQYSAKDLVEGREYKYRVFATNDSGDG-P 11061

Query: 1952  TESQSVRLEKHATVPS 1967
              +  SV  +    +PS
Sbjct: 11062 VKELSVLAKDINVLPS 11077



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 48/150 (32%), Positives = 78/150 (52%), Gaps = 16/150 (10%)

Query: 692  CSVLKIT--NVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPP-QVIEPLKS--M 744
            C  L IT  N+ +     + V AVN    GE S  I + I+  E  P  + ++  KS  +
Sbjct: 6716 CKDLTITLENLTENMMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAI 6775

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKN----NKPVKALPTKSD---GDTHSITILKPKKV 797
            IVR+G ++ + A++VG P PT  W KN    ++P +A+  +S+     T +  I  P+ V
Sbjct: 6776 IVRKGAAIEIPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESV 6835

Query: 798  K-DEGVYTLKAENSEGIAE-TSAVITVEEP 825
            + D G+Y L A N+ G+ + T  V  ++ P
Sbjct: 6836 RQDTGMYKLTATNTRGVGQRTMRVDILDRP 6865



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 7/128 (5%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860
            + +KA N  G  E S  I+V    +EN+    ++  F+   I V++   I++ A +   P
Sbjct: 6734 FRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIEIPAEIVGLP 6793

Query: 861  VPSITWYRNNEII-SPSETITQNFDGENIELVITNV----DSEIDSGDYKCVASNSAGKS 915
            +P+  W +N  +I  P+E +T   +  N + + T +        D+G YK  A+N+ G  
Sbjct: 6794 LPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGMYKLTATNTRGVG 6853

Query: 916  SHGARVTI 923
                RV I
Sbjct: 6854 QRTMRVDI 6861



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 84/425 (19%), Positives = 156/425 (36%), Gaps = 22/425 (5%)

Query: 1178  CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVI 1236
             CEV        + V  P       L + +++ A +   L  +I    +  VTW K  + I
Sbjct: 10772 CEVPEKHIAKDVFVT-PEAELDAELKDTLVLTAGSKMKLHAKIKGRPIPRVTWAKMNTNI 10830

Query: 1237  EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK---VEVVEFPPKIVDY 1293
             +D +   + +      + + K    D  +Y  + LD+ S  K+    V+V++ P   ++ 
Sbjct: 10831 KDRQGIIIKTTDTDTLVCVEKVNRYDAGKYI-LNLDSVSGMKMYTVIVKVLDTPGPPLNL 10889

Query: 1294  EREYRIKRGSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               +   K     ++L D       ++   +IV+ +  ++   +  +      S  I+ +E
Sbjct: 10890 MIKETSK--DSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVTTSCTKTSFKIEDLE 10947

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNILEIDSSSINICWDEPENTG 1408
                +  +++  +N  G  +    V  +   ++P P      L +   S  + W +P + G
Sbjct: 10948 PGRSYCFRVLAQNQYGIGEPCETVDAVRASEQPGPVMDFKTLLVTKDSCTLSWKKPISDG 11007

Query: 1409  NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
              S II YV+E       +W  +      Q S ++L     Y++R +A N+       E +
Sbjct: 11008 GSRIIAYVLEVLN-GEDKWKELLRSKNMQYSAKDLVEGREYKYRVFATNDSGDGPVKELS 11066

Query: 1469  EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--DGKKLKTAK 1526
                K I          + P  N   +   ++ L     G P P V+W +  D     T +
Sbjct: 11067 VLAKDINVLP-SCDLRDLPNLNYIAKEGSNVRLKIPIIGKPTPAVSWKKGEDENLTDTGR 11125

Query: 1527  ATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583
                E+                   Y     N  G  E++  V +  KP   I N  IK K
Sbjct: 11126 VCVESTAVNTTLLIRDCQRTDASKYTITLRNSAGTKESTIFVRVVGKP--GIPNGPIKFK 11183

Query: 1584  HKVGD 1588
                 D
Sbjct: 11184 EVTAD 11188



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 4/120 (3%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQV 533
           DEN   +Y  + +NE    +         E+ + P F +K   +H  D  G  V+ E +V
Sbjct: 763 DENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKK-PSEHIEDAEGKLVKLESRV 821

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
            G     + W++    I  S  + + +   NVA + +R+    D+G +TC A N AG AS
Sbjct: 822 SGSQPLSVIWYKDNKEINTSDIYDVSFKS-NVAVMCLRKATVTDSGVYTCSASNEAGTAS 880



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 5/122 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
             + + A NS G +  +      E  E+  EP + +     +T K    +++ A V+  P P
Sbjct: 9965  FRVAARNSMGSSLPTETREAYEIKEQMFEPKIIMTEL--VTAKAGAKLRVEALVSGKPAP 10022

Query: 863   SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             +  W R  N ++S S         +N+ ++I    S  DSG+Y  VA NS+GK     ++
Sbjct: 10023 ACQWKRGENNVVSSSRLAVHK--SQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKI 10080

Query: 922   TI 923
              I
Sbjct: 10081 II 10082



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 8/109 (7%)

Query: 709   TVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPT 765
             T V ++R  E + PI++   + E  PP++   ++  K + V+ G  V L A+V G P P 
Sbjct: 10364 TAVNISRPSEITDPILV---SAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPK 10420

Query: 766   ITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSEG 812
             +TW KN + +KA    K     H  ++      K   G Y + A N+ G
Sbjct: 10421 VTWSKNGETLKADKEFKMSQKRHLFSLSLDAVTKLHAGNYGIHAANASG 10469



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           +  + + P+F +K+    +  G+ V+FEC++E  P     WF+  + IK S   ++    
Sbjct: 217 TRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRI-ISR 275

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
              ++L +     +D+G ++C A N  G  + + +L + A
Sbjct: 276 QTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA 315



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 708  YTVVAVNREGEASLPIVLKIKT--GEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764
            + V AVN  G        K  T   E EPP + ++    ++VR GES  L  +  G P P
Sbjct: 8027 FRVSAVNEVGPGKPSFSTKPITCKDELEPPTIELDFRDKVVVRVGESFALQGRYTGKPAP 8086

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE-TSAVI 820
            +ITW +++K +KA   +  K+   T  + I+K ++    G Y +  EN  G  +    VI
Sbjct: 8087 SITWSRDDKELKADNHIKFKNTLTTMCLGIVKAQR-GHSGKYCVTVENCTGARKGICNVI 8145

Query: 821  TVEEP 825
              + P
Sbjct: 8146 VADRP 8150



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            LK   + KF+        +   GE +  + +K +T        +   + M++  G  + +
Sbjct: 7723 LKENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKMVIHAGGVIRI 7782

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAENSE 811
             A V G P P ITW ++  PV   P+++  +T SI+   ++K       GVYT+ A+N  
Sbjct: 7783 LAYVSGQPPPVITWSRDEYPV---PSEAVIETTSISCSMVIKDCTRAQRGVYTITAKNDG 7839

Query: 812  GIAETSAVITV 822
            G  + S ++ V
Sbjct: 7840 GEVKKSVIVEV 7850



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 11/136 (8%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV---IEPLKSMIVRQG 749
            ++T + + Q   Y V AVNR G AS P       +    KEPP++    + L  +  R G
Sbjct: 5009 QVTGLIEGQWYAYRVRAVNRLG-ASRPCKATDEILAVDPKEPPEIQLDAKLLAGLTARAG 5067

Query: 750  ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
              + L A V+G P P + W K +   KP + + T      HS   +      D   Y ++
Sbjct: 5068 TKIDLPADVLGKPEPRVKWTKADLVLKPEERI-TIDTKPGHSTLSIANTTRSDTATYIIE 5126

Query: 807  AENSEGIAETSAVITV 822
            A N+ G A  +  + +
Sbjct: 5127 AVNTSGRATATVDVNI 5142



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 7/101 (6%)

Query: 630   EGIPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
             E +PP      +  K   V  GSD+ LE  +   P P + W   GE +  D+   ++   
Sbjct: 10383 ENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMS--Q 10440

Query: 687   DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
               H++   L +  V K   G Y + A N  G  +  I LKI
Sbjct: 10441 KRHLFS--LSLDAVTKLHAGNYGIHAANASGNTTAEIQLKI 10479



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 5/131 (3%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQV---IEPLKSMIVRQGESV 752
            +T + +  +    V AVN  G  +  +   ++  E +E P V   I     +I+R GE++
Sbjct: 6430 VTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEPEEAPGVEFDISVRNGVIIRAGETL 6489

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSE 811
             L A V G P P + W K+           + +  S T+   K ++ D G+Y +   N  
Sbjct: 6490 RLPAVVTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPS 6549

Query: 812  GIAETSAVITV 822
            G    S  + V
Sbjct: 6550 GTKSVSVKVDV 6560



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 10/147 (6%)

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEP 740
            I  D+  +C+  ++  + +  E  + + A N+ G+   P  L      K+   PP+V   
Sbjct: 8999 INKDLIKFCA-FRVPGLNEGIEYRFRIKASNKVGDGE-PRELTETVLAKDILVPPEVTVD 9056

Query: 741  LKS---MIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKK 796
            +     + VR G+ + L  +V G P P ITW K+ + + +   T+ + +   + ++    
Sbjct: 9057 VACRDLLTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDA 9116

Query: 797  VK-DEGVYTLKAENSEGIAETSAVITV 822
            V+ D G Y ++A+NS G A+ + ++ V
Sbjct: 9117 VRADYGKYAIQAKNSSGQAQATIIVNV 9143



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 4/123 (3%)

Query: 803  YTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            + +K++N+ GI+  +TS  IT +E T       + +   + + VK   TI L A +   P
Sbjct: 8624 FRVKSQNAIGISRPDTSVPITCQEKTLAPTIE-VDVKLIEGLVVKAGSTILLPAVMLGIP 8682

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
             P+  W      +          +G +  L I+   +  DSG+Y    SN AG  S    
Sbjct: 8683 TPTAKWQSEGNELKTEGKFKIVTEGNSTTLTISEC-ARTDSGEYSLTVSNPAGSKSVALH 8741

Query: 921  VTI 923
            VT+
Sbjct: 8742 VTV 8744



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGES 751
            +T + + +E  + V A N  G  + S    L +     +PPQV         + +++GE 
Sbjct: 6003 VTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLSIKKGEE 6062

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTK 781
            + L A + G+P PT+TW +N++ V+  P K
Sbjct: 6063 IRLDAYISGSPYPTVTWLRNDENVRQPPAK 6092



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +TV+    I LV RV   P P ITW ++  ++   +    N +   +ELVI +     D 
Sbjct: 9063 LTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDA-VRADY 9121

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILE 949
            G Y   A NS+G++   A + ++V  +    ++L+ +Y T++   V  E
Sbjct: 9122 GKYAIQAKNSSGQAQ--ATIIVNVLDIPGACQNLKVAYVTKDSCMVSWE 9168



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/121 (22%), Positives = 57/121 (47%), Gaps = 6/121 (4%)

Query: 708  YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            + V   N  GE++     ++   E+  +P   ++ + +++V+ G++V + A+++G P+P 
Sbjct: 9318 FRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKPQPE 9377

Query: 766  ITWCKNNKP---VKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            + W K        K L  + +  T+   + L   +  D G Y + A N+ G     A + 
Sbjct: 9378 VKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEAKVN 9437

Query: 822  V 822
            V
Sbjct: 9438 V 9438



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+ ++ E  V G P P   W R    +  S    ++    N+  L+I++V  +D+G ++ 
Sbjct: 10007 GAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVH-KSQNMCVLIIKDVSRQDSGEYSL 10065

Query: 584   VAKNAAGFASSTTELIV 600
             VA+N++G    T ++I+
Sbjct: 10066 VAENSSGKIEQTLKIII 10082



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 17/45 (37%), Positives = 27/45 (60%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
            + KP PP K ++LEI  +S  + W +P   G + I  YV++Y E+
Sbjct: 9850 VSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVIDYLEL 9894



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 10/149 (6%)

Query: 695   LKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVRQGE 750
             + I  +K+ ++  + V A N  G +SLP       +IK    EP  ++  L  +  + G 
Sbjct: 9952  ISIAGLKEGRKYRFRVAARNSMG-SSLPTETREAYEIKEQMFEPKIIMTEL--VTAKAGA 10008

Query: 751   SVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
              + + A V G P P   W +  NN    +           + I+K    +D G Y+L AE
Sbjct: 10009 KLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAE 10068

Query: 809   NSEGIAETSAVITVEEPTEENAEPPLFIN 837
             NS G  E +  I + +      EPP  I+
Sbjct: 10069 NSSGKIEQTLKIIIRD-IPGPPEPPFEIS 10096



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 524  GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            GS+  FECQ+   P   IT W +  + I+ S   + +  D     L I +V   D G +T
Sbjct: 2676 GSSAVFECQIS--PSTAITTWMKDGSNIRESPKHK-FTSDGKDRKLQIIDVQLSDTGEYT 2732

Query: 583  CVAKNAAGFASSTTELIVE 601
            CVAK      +ST +L+VE
Sbjct: 2733 CVAKLGNKEKTSTAKLVVE 2751



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 2/124 (1%)

Query: 802  VYTLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            +Y  + +      E++ V T E    EE  +P L +     + VK    + + A +   P
Sbjct: 9315 IYQFRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKP 9374

Query: 861  VPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             P + W +  +    S+ +  Q   G N   +  +     D+G Y   A+N+AG  S  A
Sbjct: 9375 QPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEA 9434

Query: 920  RVTI 923
            +V +
Sbjct: 9435 KVNV 9438



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA---VITVEEPTEENAEP 832
            + +P    G ++++T L   K   E  + ++AEN  G ++ S    +I   +P +   + 
Sbjct: 5990 RCVPNLVPGFSYTVTGLTEGK---EYQFRVRAENIAGASDPSRSTPLIMAADPVDP-PQV 6045

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
             LF      +++K+   I+L A ++ +P P++TW RN+E
Sbjct: 6046 TLFARIASGLSIKKGEEIRLDAYISGSPYPTVTWLRNDE 6084



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 2/112 (1%)

Query: 1297  YRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
             Y  K GS+V L +     P P   W     + +           + + +L I+  + TDA
Sbjct: 11088 YIAKEGSNVRLKIPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDA 11147

Query: 1356  GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406
               Y + L N+ G  +  + V ++ KP  P  P    E+ +    + W  P++
Sbjct: 11148 SKYTITLRNSAGTKESTIFVRVVGKPGIPNGPIKFKEVTADGATLKWSAPKD 11199



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 9/168 (5%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G+ I L   ++  PEP + W      + P+E I++    D     S L I N  +    T
Sbjct: 5067 GTKIDLPADVLGKPEPRVKWTKADLVLKPEERITI----DTKPGHSTLSIANTTRSDTAT 5122

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y + AVN  G A+  + + I   +  PP   +   S I  +   +  +A       P   
Sbjct: 5123 YIIEAVNTSGRATATVDVNI-LDKPGPPAAFD--ISEITNESCCLAWNAPRDDGGSPVAN 5179

Query: 768  WCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGI 813
            +    +P      +    T   T  K  K+    E V+ + AEN  GI
Sbjct: 5180 YIVEMRPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYGI 5227



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 1/72 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +    +V+G P P+ITW +   ++   +  +M  ++  +  LVI++    D G +  
Sbjct: 9068 GQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEM-NNNFPLVELVIQDAVRADYGKYAI 9126

Query: 584  VAKNAAGFASST 595
             AKN++G A +T
Sbjct: 9127 QAKNSSGQAQAT 9138



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 50/226 (22%), Positives = 91/226 (40%), Gaps = 22/226 (9%)

Query: 705   EGTYTVVAVNREGEASLP-----IVLKIKTGEKEPPQVIEPLKSMIV-------RQGESV 752
             E T+ V A+NR G+         I  +        P+V++  K+ +          G S 
Sbjct: 10255 EYTFRVSAINRAGQGKPSKKTDFITARTPVDAPGKPEVLDVTKNAVSLVWTKPKNDGGSK 10314

Query: 753   ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             I+   V     P  TW + N   + +P +     ++ T L+        V    A N   
Sbjct: 10315 IIGYYVEAMRLPGDTWVRCNTSSQNVPREE----YTATGLEEGANYQFRVIAKTAVNISR 10370

Query: 813   IAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
              +E +  I V   + EN  P   L +   + + VK    + L A V   P+P +TW +N 
Sbjct: 10371 PSEITDPILV---SAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNG 10427

Query: 871   EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             E +   +    +       L +  V +++ +G+Y   A+N++G ++
Sbjct: 10428 ETLKADKEFKMSQKRHLFSLSLDAV-TKLHAGNYGIHAANASGNTT 10472



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             GS V  E +V G P P++TW +    +K  ++F+M     ++ +L +  V    AG +  
Sbjct: 10404 GSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKM-SQKRHLFSLSLDAVTKLHAGNYGI 10462

Query: 584   VAKNAAGFASSTTEL-IVEAP 603
              A NA+G  ++  +L I++ P
Sbjct: 10463 HAANASGNTTAEIQLKILDIP 10483



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 39/174 (22%), Positives = 70/174 (40%), Gaps = 12/174 (6%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  GS ILL   ++ IP P   W  +G E+  +    +  E +     + L I+   +  
Sbjct: 8666 VKAGSTILLPAVMLGIPTPTAKWQSEGNELKTEGKFKIVTEGN----STTLTISECARTD 8721

Query: 705  EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
             G Y++   N  G  S+ +   VL + +    P  ++E     ++ Q  +        G+
Sbjct: 8722 SGEYSLTVSNPAGSKSVALHVTVLDVPSAPVGPVNILEVTPDHMIIQWRA---PKDDGGS 8778

Query: 762  PRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            P  +    K +  KP +     S G T +   +   +   E +  ++AEN  GI
Sbjct: 8779 PLMSYVVEKKDVKKPWEPWSVVSSGSTSTKAKVPRLEKGREYIVRVRAENKIGI 8832



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 16/146 (10%)

Query: 775  VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            VKA   +  G    IT LK   +    V  L   N+ G+ E   V    E  +    P L
Sbjct: 7706 VKAKDKEVRGTKFVITGLKENALFKFRVIAL---NAAGLGEPGEVADALEMKDRTILPVL 7762

Query: 835  FINRFQEITVKEK------GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
             +    +++VKEK      G I+++A V+  P P ITW R +E   PSE + +     + 
Sbjct: 7763 EL----DVSVKEKMVIHAGGVIRILAYVSGQPPPVITWSR-DEYPVPSEAVIET-TSISC 7816

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGK 914
             +VI +  +    G Y   A N  G+
Sbjct: 7817 SMVIKDC-TRAQRGVYTITAKNDGGE 7841



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  G  + +E  L+  P+P++ W  +G+     + + V +E+  +   + L+++N ++  
Sbjct: 9358 VKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNF--TKLQLSNSRRGD 9415

Query: 705  EGTYTVVAVNREGEAS 720
             G Y + A N  G  S
Sbjct: 9416 TGKYIITATNAAGTCS 9431



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ +     V G P P++ W +   ++KP +   +     + +TL I      D  T+  
Sbjct: 5067 GTKIDLPADVLGKPEPRVKWTKADLVLKPEERITIDTKPGH-STLSIANTTRSDTATYII 5125

Query: 584  VAKNAAGFASSTTEL-IVEAP 603
             A N +G A++T ++ I++ P
Sbjct: 5126 EAVNTSGRATATVDVNILDKP 5146



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 743   SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800
             ++++  G  + L A++ G P P +TW K N  +K         T + T++  +KV   D 
Sbjct: 10798 TLVLTAGSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDA 10857

Query: 801   GVYTLKAENSEGIAETSAVITV 822
             G Y L  ++  G+   + ++ V
Sbjct: 10858 GKYILNLDSVSGMKMYTVIVKV 10879



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 18/187 (9%)

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP-KKVKDEGVYTL 805
            R G S I    V      +  W + N P K + T S    +++  LK  KK +   V   
Sbjct: 7097 RDGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNS----YTVPGLKENKKCRFRIVAVN 7152

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGT-IKLVARVTRNPVPS 863
             A  SE    TS +I V++  EE   P + I+   QE+     GT +K+ A ++  P+P+
Sbjct: 7153 AAGESEPSPRTSDII-VQDILEE---PVITIDVTSQELLNCRAGTTLKIPATISGKPLPN 7208

Query: 864  ITWYRNNEIISPSET------ITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSS 916
            +TW  +    S  +       +  +    +   V+T  +S++  SG Y   A+N AG   
Sbjct: 7209 VTWEFDGTAPSEKKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKI 7268

Query: 917  HGARVTI 923
               RV +
Sbjct: 7269 VKVRVNV 7275



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P +    + ++V +GE + +       P+P++ W K +  +K    L    + +   + +
Sbjct: 5749 PTIDVATQDIVVVEGEKMDIKIPYRAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLEL 5808

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            LK K  +D GVYT+  ENS G    +  +TV
Sbjct: 5809 LKCKH-EDAGVYTVTLENSLGSVTGTVSVTV 5838



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 14/45 (31%), Positives = 24/45 (53%)

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +W  +G+E++     ++  +G    L I +C   D+GEYS  V N
Sbjct: 8687 KWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSN 8731


>UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Homo
             sapiens (Human)
          Length = 34350

 Score =  299 bits (733), Expect = 7e-79
 Identities = 200/685 (29%), Positives = 321/685 (46%), Gaps = 41/685 (5%)

Query: 1292  DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKV 1350
             D  +   ++ G  + L V  +  P P   W   +  ++     +  +D KS    T  + 
Sbjct: 20625 DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRD----RIGLDIKSTDFDTFLRC 20680

Query: 1351  ENT---DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
             EN    DAG Y L LEN+CG  +  + V +LD P PP    + EI   S  + W+ P   
Sbjct: 20681 ENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIID 20740

Query: 1408  GNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             G S II YVV+ ++ +   W +V    +KT   + NL+   SY FR +A NE  I D  E
Sbjct: 20741 GGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE 20800

Query: 1467  TTEYYKVIKETKIQSPTVEKPLKNITT--------EPNEDIELTCIFGGVPQPKVTWYRD 1518
             T +    +K ++   P V+  +++++         +P+ D   + I G V        + 
Sbjct: 20801 TRD---AVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGG-SRIIGYVVDFLTEENKW 20856

Query: 1519  GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
              + +K+    Y  +               ++  A N++GE   S +  + +  V+    +
Sbjct: 20857 QRVMKSLSLQYSAKDLTEGKEYT------FRVSAENENGEGTPSEITVVARDDVVAPDLD 20910

Query: 1579  -----DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
                  D+    K    + +   I+G P P V W K  + L  D   ++ +    + + + 
Sbjct: 20911 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVY 20970

Query: 1634  ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             + ++S + KYTI   N AGT    +++KV  KP  P GP+   E++ E++T++W PP DD
Sbjct: 20971 DCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDD 21030

Query: 1694  GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
             GG E+T Y +EK +  NN+W+  A   +   T+ + +L+E  EY FRV A+N  G  E L
Sbjct: 21031 GGSEITNYILEKRDSVNNKWVTCASAVQKT-TFRVTRLHEGMEYTFRVSAENKYGVGEGL 21089

Query: 1754  ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812
             +SEPIV +   DVP           + ++SV +TW   +K GGSPI  Y +E K+     
Sbjct: 21090 KSEPIVARHPFDVPD-APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 21148

Query: 1813  WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
             WK            ++  L+    Y+FR+ A N  G   P    + +     + PP +P 
Sbjct: 21149 WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPE 21208

Query: 1871  NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
                V   T  SVTL WTEP+ +GG  +T YI+E + +  KSW K   V        + ++
Sbjct: 21209 ---VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 21265

Query: 1931  KEKDEIIFRISAENTVG-VSLPTES 1954
              E  +  FRI A+NT G +S P+ES
Sbjct: 21266 VEGGKYEFRIRAKNTAGAISAPSES 21290



 Score =  290 bits (711), Expect = 3e-76
 Identities = 346/1472 (23%), Positives = 590/1472 (40%), Gaps = 117/1472 (7%)

Query: 636   FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
             F+K      V E   I L C  V+ P  ++ W    EEI+      +  E        +L
Sbjct: 13392 FTKNLANIEVSETDTIKLVCE-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKR----IL 13446

Query: 696   KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
              I N      G Y     +   +       K+K  E     + +P +++ + +GE     
Sbjct: 13447 VIQNAHLEDAGNYNCRLPSSRTDG------KVKVHELAAEFISKP-QNLEILEGEKAEFV 13499

Query: 756   AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
               +     P + W +++K +++       +DG    + ++K   ++D G Y +      G
Sbjct: 13500 CSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR-VLVVKDATLQDMGTYVVMV----G 13553

Query: 813   IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
              A  +A +TV E           +   ++  VKE+  +     V      +  W+RN E 
Sbjct: 13554 AARAAAHLTVIEKLR-------IVVPLKDTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEA 13605

Query: 873   ISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVT 929
             I  S    I Q      + +   ++D   D  +Y    +N  G++    A + ++ E + 
Sbjct: 13606 IFDSSKYIILQKDLVYTLRIRDAHLD---DQANYNVSLTNHRGENVKSAANLIVEEEDLR 13662

Query: 930   FVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
              V+ L K  ET E K+V   C+ +   V+ KW  N +E+   D+R   +  +        
Sbjct: 13663 IVEPL-KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVP-FDNRVSYRVDKYKHMLTIK 13720

Query: 989   XXXX-DVG-VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                  D G  I    +D+  + +L++ E   EF+  L+D  V E D A+   +++ E A+
Sbjct: 13721 DCGFPDEGEYIVTAGQDKSVAELLII-EAPTEFVEHLEDQTVTEFDDAVFSCQLSREKAN 13779

Query: 1047  VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
             V W R+G  IK  K KY FEK G I +L I++  + DE EY+C + D    A + V E+P
Sbjct: 13780 VKWYRNGREIKEGK-KYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIP 13838

Query: 1107  PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
              EII   Q+     G    F  EL K    V+W ++   +   +  Q+  +GK  +L+I 
Sbjct: 13839 VEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQIC 13898

Query: 1167  DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL- 1225
             D    D GEY     + +  A L +        ++  +  LV  +    LT+ +P +   
Sbjct: 13899 DIKPRDQGEYRFIAKDKEARAKLELAAAP---KIKTADQDLV-VDVGKPLTMVVPYDAYP 13954

Query: 1226  --DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
               +  W+K+    E     T+ +  ++ +  I +  + D+  Y  VL +   K+   + +
Sbjct: 13955 KAEAEWFKEN---EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINL 14011

Query: 1282  EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKPSID 1339
             +V++ P  + + E         +V+L  +       +    ++V  + IK+      +  
Sbjct: 14012 KVIDVPGPVRNLEVTETFD--GEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDR 14069

Query: 1340  SKSASLTIKKVENTDAG-IYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEI 1392
             ++S   T+  ++      ++++   N  G  + VE +  +      D P PP    I ++
Sbjct: 14070 AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDV 14129

Query: 1393  DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450
             +   +++ W+ PE  G + I  YV+E ++  +  W +   +     S  + ++     Y 
Sbjct: 14130 NRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS 14189

Query: 1451  FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVP 1509
             FR  A N + +   S  T + KV    +  SP V     + T    +   E     GG P
Sbjct: 14190 FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSP 14249

Query: 1510  ----------QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
                       + K  W R   KL   + TY+                 Y+  A N  G  
Sbjct: 14250 ILGYIIERCEEGKDNWIRCNMKL-VPELTYK------VTGLEKGNKYLYRVSAENKAGVS 14302

Query: 1560  ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE------GIPPPEVIWYKNGNKL 1613
             + S ++G        +         K G E +V   I       G P P   W      L
Sbjct: 14303 DPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVL 14362

Query: 1614  ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
             E      + T    + + I   +RS    YT++  N   T S E+ + V  +PS P+  +
Sbjct: 14363 ETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPK-EL 14421

Query: 1674  IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733
                +I+++SV + W+PP DDGG  LT Y +EK E     W KV D   D+E + +  L +
Sbjct: 14422 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLE-FTVPDLVQ 14480

Query: 1734  NCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
               EY+F+V A+N  G  E A   EP+ + T   VP             N S+++TW P +
Sbjct: 14481 GKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTAN-SIFLTWDPPK 14539

Query: 1793  KNGGSPIIDYKVEIKQEGK-KWKX-XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
              +GGS I  Y VE    G  KW             +  L     Y +R+ A N  G S P
Sbjct: 14540 NDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 14599

Query: 1851  YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
                 ++I    T   P    +  +    +     K   P +  G P      E K     
Sbjct: 14600 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP------EPKI---- 14649

Query: 1911  SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV----- 1965
             +WTK   +        IEN+ +K  +    S  +  G  +  E+ +V     A V     
Sbjct: 14650 TWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYI-IEAVNVCGRATAVVEVNVL 14708

Query: 1966  --PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
               P PP A  +I  V +   + +W  P  DGG+ +  Y +  R     +W ++    V  
Sbjct: 14709 DKPGPPAA-FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKD 14766

Query: 2024  LKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
               F    L  N  Y+ R+ A N  G+ EP+++
Sbjct: 14767 TNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 14798



 Score =  283 bits (695), Expect = 3e-74
 Identities = 321/1444 (22%), Positives = 574/1444 (39%), Gaps = 102/1444 (7%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V  G     +C L +  +  + W  KG+++ P + +    E  +H     L + +VK   
Sbjct: 13134 VTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVH----TLTLRDVKLED 13188

Query: 705   EGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPR 763
              G   + A + +  A+L +        KEPP +  +PL+   V +G + +L  +V     
Sbjct: 13189 AGEVQLTAKDFKTHANLFV--------KEPPVEFTKPLEDQTVEEGATAVLECEV-SREN 13239

Query: 764   PTITWCKNNKPV---KALPTKSDGDTHSITI--LKPKKVKDEGVYTLKAENSEGIAETSA 818
               + W KN   +   K     +DG    + I    P+ +K    YT  A++ +    TS 
Sbjct: 13240 AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIK---TYTCDAKDFK----TSC 13292

Query: 819   VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
              + V  P  E      F+    ++ V+EK   +    ++R     + W+++   I   + 
Sbjct: 13293 NLNVVPPHVE------FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKK 13345

Query: 879   ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                   G  + +++ N     D  +Y C    +  ++S    +T+  E+  F K+L  + 
Sbjct: 13346 YDIISKGA-VRILVINKCLLDDEAEYSCEVRTA--RTS--GMLTVLEEEAVFTKNLA-NI 13399

Query: 939   ETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
             E  E  T+ L C+ S       WY   +EI      EI+ EGR            D G  
Sbjct: 13400 EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNY 13459

Query: 998   KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
              C +    T   + V E   EFI K Q+ E+ E + A     I+ E+  V W+RD + ++
Sbjct: 13460 NCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLE 13519

Query: 1058  PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
                +KYD    G  R L +++ ++ D G Y  ++      A +TV+E    I+  L++ +
Sbjct: 13520 -SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTR 13577

Query: 1118  VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
             V +  +  F  E+    A  +WF++   I  S+   +        L+I D  LDD   Y+
Sbjct: 13578 VKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYN 13637

Query: 1178  CEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
               + N      K  A L VEE  +     L +   +   +  +   ++    + + W K 
Sbjct: 13638 VSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWC-KVNRLNVTLKWTKN 13696

Query: 1233  KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292
                +    + +   D  K  L I+ C   D+ EY       KS  +L +  +E P + V+
Sbjct: 13697 GEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLI--IEAPTEFVE 13754

Query: 1293  YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
             +  +  +    D           + N +W  N + IK+ K  K   D     L IK    
Sbjct: 13755 HLEDQTVTEFDDAVFSCQLSR-EKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 13813

Query: 1353  TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
              D   Y   +E+    A + +    ++   PP   +ILE   + +    +  ++      
Sbjct: 13814 DDECEYACGVEDRKSRARLFVEEIPVEIIRPP--QDILEAPGADVVFLAELNKDKVEVQW 13871

Query: 1413  IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             +   +   + D  + +S   I + Q      +    YRF         I+   E     +
Sbjct: 13872 LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRF---------IAKDKEARAKLE 13922

Query: 1473  VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-TYEN 1531
             +    KI++       +++  +  + + +   +   P+ +  W+++ + L T    T   
Sbjct: 13923 LAAAPKIKTAD-----QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAE 13977

Query: 1532  RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDE 1589
             +               YK +  N HG+ E    + +   P   + N ++ +    +V   
Sbjct: 13978 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG-PVRNLEVTETFDGEVSLA 14036

Query: 1590  WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSK-YTIEA 1647
             W       G    ++I Y    +    K + + T    S    +  L++      + + A
Sbjct: 14037 WEEPLTDGG---SKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSA 14093

Query: 1648  SNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
              N  GT   VE    V     YD P  P   V + +++R  V++ W+PP  DGG E+T Y
Sbjct: 14094 RNRVGTGEPVETDNPVEARSKYDVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNY 14152

Query: 1702  AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-I 1760
              IE  +  + RW     V  +  +  +  + E  EY FRV AQN +G  +   + P V +
Sbjct: 14153 VIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKV 14212

Query: 1761  KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXX 1817
                ++ PS            + SV + W P  K+GGSPI+ Y +E  +EGK  W      
Sbjct: 14213 ADPIERPSPPVNLTSSDQTQS-SVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMK 14271

Query: 1818  XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSE 1876
                    ++  L     Y +R+ A N+ G S P      +T       P+   + F    
Sbjct: 14272 LVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 14331

Query: 1877  STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936
                    +    P +    P   +    K ++     K+ T+  +  E  I   +  D+ 
Sbjct: 14332 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL-SAYAELVISPSERSDKG 14390

Query: 1937  IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDG 1994
             I+ +  EN V        +++  E    V + P+AP E++   +  + V  +W  P+ DG
Sbjct: 14391 IYTLKLENRV--------KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG 14442

Query: 1995  GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
             G+PL GY +  R+V++  W +V    V  L+F + DL +   Y+ ++ ARN+ G  EP  
Sbjct: 14443 GSPLTGYVVEKREVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAY 14501

Query: 2055  SDEP 2058
              DEP
Sbjct: 14502 VDEP 14505



 Score =  276 bits (676), Expect = 6e-72
 Identities = 202/711 (28%), Positives = 312/711 (43%), Gaps = 35/711 (4%)

Query: 1287  PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-- 1341
             PP+++   +  RE  IK G  + L    +  P P   W    K   +   TK  ID    
Sbjct: 18142 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTW----KKEDRDAPTKARIDVTPV 18197

Query: 1342  SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
              + L I+   + D GIY L +EN  G   V + V +LDKP PP    + EI   S  + W
Sbjct: 18198 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTW 18257

Query: 1402  DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVD 1460
              EP + G S I  YVVE +++ + +W  +   +K ++   ++L   + Y FR  A N+  
Sbjct: 18258 KEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 18317

Query: 1461  ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVPQPK--VT 1514
                  ET +  K +    +  P   K L ++  +  E + L        GG P     V 
Sbjct: 18318 RGPFVETPKPIKALDP--LHPPGPPKDLHHVDVDKTE-VSLVWNKPDRDGGSPITGYLVE 18374

Query: 1515  WYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             +  +G +      T  N                  K       G  +T+  +  Q+K V 
Sbjct: 18375 YQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVP 18434

Query: 1574  TISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
                  D+K       K G      A+I G+P P   W  +G++++ D+ Y + T   +SV
Sbjct: 18435 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 18494

Query: 1630  IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
             + IK   R  + +Y I  SN AG+ +V V L V D P  P GP+ + +++ E +TI W+P
Sbjct: 18495 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 18554

Query: 1690  PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
             P DDGG  +  Y +EK +   + W  V+      +   I  L + CEY+FRV A+N +G 
Sbjct: 18555 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLK-IPHLQKGCEYVFRVRAENKIGV 18613

Query: 1750  SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809
                L+S P V K     PS           +N +  ++W   + +GGSPI  Y +E ++ 
Sbjct: 18614 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT-VSWTLPKSDGGSPITGYYMERREV 18672

Query: 1810  GKKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
               KW             R+  L    TY+FR++A N  G S P  S D I   + + PP 
Sbjct: 18673 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 18732

Query: 1868  QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC- 1926
              P N  + + +  +  L WT+P S+GGSPI  Y++E +      W +I      +   C 
Sbjct: 18733 PPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINK--DELIRQCA 18790

Query: 1927  --IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
               +  + E +E  FRI A N VG   P E     + K   +  PP   L++
Sbjct: 18791 FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK--DILHPPEVELDV 18839



 Score =  267 bits (654), Expect = 3e-69
 Identities = 275/1199 (22%), Positives = 476/1199 (39%), Gaps = 92/1199 (7%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+ + P F  KL+  H   G  V FEC++ G    Q++W++   ++K   + Q  +   
Sbjct: 8037 KERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF-VH 8095

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
            NVATL I +      G + C A N  G ASS+ +LI    LS+H                
Sbjct: 8096 NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLI----LSEH---------------- 8135

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                    +PP F  KP +  +  G     +C +       I W     EI P  N  + 
Sbjct: 8136 -------EVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 8188

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK- 742
            +  +     + L +  V K   G YT  A N  G+ S    L    G +EPP+ I+ L+ 
Sbjct: 8189 LVEN----TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHL----GVQEPPRFIKKLEP 8240

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--KVKDE 800
            S IV+Q E      ++ G+P   + W K+   ++           S+ +L+     V+D 
Sbjct: 8241 SRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 8300

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            G YT +A N+ G A +S  + V+       EPP+F  +   I   +   + L   +   P
Sbjct: 8301 GDYTCEAHNAAGSASSSTSLKVK-------EPPIFRKKPHPIETLKGADVHLECELQGTP 8353

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
               ++WY++   +   +      +     + I NVD+  D G+Y+C A+N  G  +    
Sbjct: 8354 PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDA-ADIGEYQCKATNDVGSDTCVGS 8412

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEI-SGMDHREIIQ 977
            + +      FVK L     T  GK V L+   + +  +S  W+ +K EI    D+  I  
Sbjct: 8413 IALKAPP-RFVKKL-SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 8470

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
                           + G   C +K+    QE    L V E     + K +  +V   D 
Sbjct: 8471 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP-ATIVEKPESIKVTTGDT 8529

Query: 1034 AILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
              LE  +  +      W +DG+ +    NKY       +  L I N +  D G YS  ++
Sbjct: 8530 CTLECTVAGTPELSTKWFKDGKEL-TSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 8588

Query: 1093 D----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE 1145
            +    +SCTA + V +  +PP    +L+      G+    E ++     + V WF +G+E
Sbjct: 8589 NPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNE 8648

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201
            I      Q T+      L +   +  D+G+Y+C      G+ +C+A LTV EP       
Sbjct: 8649 ISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKP 8708

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
             P  +L   N   + ++        V+W+K  S +   ++  +  +     L +      
Sbjct: 8709 DPMDVLTGTNV-TFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTS 8767

Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
               EYTC++ +          + ++ P K V    +Y I++G  + L   +   P  +  
Sbjct: 8768 QSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 8827

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W  N   +   +    +   KSA L I      DAG Y   +EN  G       + IL+ 
Sbjct: 8828 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 8887

Query: 1381 P--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQ 1437
            P      +P  + +  S+   C  +   T    + +Y  + +   TT + +  +N   T 
Sbjct: 8888 PYFVKQLEPVKVSVGDSASLQC--QLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
                 +  N S  +   A N V   + S +T  +  ++E K+  P+  + L+++      
Sbjct: 8946 V-FNQVDINDSGEYICKAENSV--GEVSAST--FLTVQEQKL-PPSFSRQLRDVQETVGL 8999

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAF 1553
             +   C   G     V+WY+DGK LK +     +  +N                Y C A 
Sbjct: 9000 PVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 9059

Query: 1554 NDHGEVETSCVVGI---QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
            N  G   +S  + +   +  P   I    +     VG+       + G  P +V W K+ 
Sbjct: 9060 NPIGSASSSARLILTEGKNPPFFDIRLAPVDA--VVGESADFECHVTGTQPIKVSWAKDS 9117

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
             ++ +  +Y I+  E ++ + + ++ +  S +YT  A N  G  S    L + ++   P
Sbjct: 9118 REIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPP 9176



 Score =  262 bits (643), Expect = 6e-68
 Identities = 222/868 (25%), Positives = 365/868 (42%), Gaps = 58/868 (6%)

Query: 1228  TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287
             TW     V+E  ++  + +      L+I      D+  YT  L +   T   +++V    
Sbjct: 14354 TWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIA 14413

Query: 1288  PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDS 1340
                   E ++      D+T    +  +  P+D+       ++V  + + +   TK     
Sbjct: 14414 RPSAPKELKF-----GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV 14468

Query: 1341  KSASLTIKKVENTDAGIYKLRLENNCG-----HADVEMNV-TILDKPSPPGKPNILEIDS 1394
                  T+  +      ++K+   N CG     + D  +N+ T    P PP      +  +
Sbjct: 14469 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 14528

Query: 1395  SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRA 1453
             +SI + WD P+N G S I  Y+VE     + +W++  + + +T+  +  L+    Y +R 
Sbjct: 14529 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRV 14588

Query: 1454  YAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A+N    S  S  TE  + +   +     ++ K L  +T +    IEL     G P+PK
Sbjct: 14589 KALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPK 14648

Query: 1513  VTWYRDGKKLKTAK-ATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             +TW +    LK  K  T EN   +               Y   A N  G       V + 
Sbjct: 14649 ITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVL 14708

Query: 1569  QKP-------VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
              KP       +  ++NE            G   +   V+E       +W+K  + +++  
Sbjct: 14709 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD-- 14766

Query: 1618  EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPV 1673
                 T  + T +I  KE        + + A N  G      +  +T K    P  P   +
Sbjct: 14767 ----TNFKATKLIPNKEY------IFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRL 14816

Query: 1674  IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733
                +I++++VT+ W  P DDGG  +T Y +E+ +PD ++W++   +     TY ++ L  
Sbjct: 14817 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 14876

Query: 1734  NCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
               +Y FRV+A+N  G  +  +S EPI+IK  +D P           +   SV + W   E
Sbjct: 14877 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPID-PPWPPGKPTVKDVGKTSVRLNWTKPE 14935

Query: 1793  KNGGSPIIDYKVEIKQEG-KKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
              +GG+ I  Y +E+ + G  +W +           +  L     Y FR+ A N+ G S P
Sbjct: 14936 HDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEP 14995

Query: 1851  YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
                 D +   + L PPS PR   V   T  +  LKWT PE +GGSPITNYI+E + V+ K
Sbjct: 14996 SEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK 15055

Query: 1911  SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPP 1969
              W  + T      +  +  + E    +FR++AEN +G S  TE +   L K   T P PP
Sbjct: 15056 GWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPP 15114

Query: 1970  TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029
              A L +  V    V   W  P+ DGG P+  Y I  ++   T W++ GK       F + 
Sbjct: 15115 YA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVT 15173

Query: 2030  DLSENHTYMIRIYARNEIGLSEPLESDE 2057
             D+ E      ++ A NE G+  P E  E
Sbjct: 15174 DVIEGTEVQFQVRAENEAGVGHPSEPTE 15201



 Score =  261 bits (640), Expect = 1e-67
 Identities = 260/1070 (24%), Positives = 452/1070 (42%), Gaps = 66/1070 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+F+++ K      G  + L CRL       + W   G  +  DEN+  +   ++   
Sbjct: 7100 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNV--- 7156

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + LKI        G Y+  A N  G AS    L  +  +K P   I+P+ S+ V  GES
Sbjct: 7157 -ATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV-SIDVIAGES 7214

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
                  V G     ITW K+NK ++          G+T  + ILK  K  D G YT +A 
Sbjct: 7215 ADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK-GDSGQYTCQAT 7273

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867
            N  G    SA ++V+       EPP F+ + +   V ++G +I+L  +++ +P   ++W+
Sbjct: 7274 NDVGKDMCSAQLSVK-------EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF 7326

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            RN+  +  S     +F   ++ L+  N  S  DSGDY C A N  G +S    +T+    
Sbjct: 7327 RNDSELHESWKYNMSFI-NSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 7385

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            V   K         +G  VIL+C+ S T      W  ++K++      +I  +       
Sbjct: 7386 VFTQK--PSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443

Query: 986  XXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                   DVG   C   ++   +T +  V  +  P F++KL D      D   L   +  
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEG 7503

Query: 1043 -ETADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----C 1096
             +   VVW +D GE+I+  +N        +I  L + +    + G+Y C +++++    C
Sbjct: 7504 FQPISVVWLKDRGEVIRESENT-RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMREC 7562

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
            +A +TV+E P  II + +   V  GN    E  +T    L  +WFKDG E+   +   +T
Sbjct: 7563 SAVLTVLE-PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHIT 7621

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEFILVPANTD 1213
               K   LKI   ++ D G YS EV NS   +  TV   S++ + R+  P FI    + +
Sbjct: 7622 FINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTV---SVHVSDRIVPPSFIRKLKDVN 7678

Query: 1214 AYLTVEIPDE-------TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            A L   +  E        + V W++  + I    K          TL +      D   Y
Sbjct: 7679 AILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIY 7738

Query: 1267 TCVLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            TCV  +   + +   V  V+ PP          +  G  +T     +  P    +W   S
Sbjct: 7739 TCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS 7798

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
            + +   +    S++     L + +V+  ++G Y   + N+ G A    ++ + +  +   
Sbjct: 7799 RELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVK 7858

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
            +     +++ S  +   E   TG   I + ++ +   I  +E  S+  +T+  T ++ L+
Sbjct: 7859 RLADFSVETGSPIVL--EATYTGTPPISVSWIKDEYLISQSERCSI-TMTEKSTILEILE 7915

Query: 1445 -TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
             T   Y   +  +      D  E          + ++ P   +PL+++     E   L C
Sbjct: 7916 STIEDYAQYSCLIENEAGQDICEAL-------VSVLEPPYFIEPLEHVEAVIGEPATLQC 7968

Query: 1504 IFGGVPQPKVTWYRDGKKLKTA---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
               G P+ +++WY++  KL++A   K  ++N                 Y C A N  G V
Sbjct: 7969 KVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAV 8028

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             +S V+ I+++ +       +K  H+ +G        I G  P +V WYK+G  L++D  
Sbjct: 8029 ASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN 8088

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLKVYDKP 1666
               +     + ++I +  +SH  +Y   ASN  GT  SS ++ L  ++ P
Sbjct: 8089 LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVP 8138



 Score =  261 bits (640), Expect = 1e-67
 Identities = 196/695 (28%), Positives = 303/695 (43%), Gaps = 41/695 (5%)

Query: 1282  EVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP-SI 1338
             E +E P   +D E  +   I+ G  + L V  +  P P  +W    K+  + +      +
Sbjct: 23862 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDV 23918

Query: 1339  DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
              S   SL +  V   D+G Y L LEN+ G     + V +LD PSPP    + EI   S++
Sbjct: 23919 TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVS 23978

Query: 1399  ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             I W+ P   G S I  Y+VE +E     + +V  N  K    I  L+   SY FR  A N
Sbjct: 23979 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAEN 24038

Query: 1458  EVDISDASETTEYYKVIKETKIQSP-TVEKPLKNIT----TEPNEDIELTCIFGGVP-QP 1511
             E  I   ++T +  KV +  +     TV+   +N      T+P  D     I   V  Q 
Sbjct: 24039 EYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQA 24098

Query: 1512  KVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-SCVVGIQQ 1569
             K +  + +  ++K+ +A   N                ++ +A N+ G  +  S  V I  
Sbjct: 24099 KHSEKWSECARVKSLQAVITN--------LTQGEEYLFRVVAVNEKGRSDPRSLAVPIVA 24150

Query: 1570  KPVITISNEDIKQKH-----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
             K ++     D+K        +VG +  +   I G P P + W K+G  L+     N+T  
Sbjct: 24151 KDLVI--EPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 24208

Query: 1625  EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
                + + IKE  +    +Y I  +N  G  +  + +   DKP  P+GPV   ++S ES+T
Sbjct: 24209 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 24268

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             + W PPL  GG ++T Y ++K +     W +  A V R   T  + KL    EY FR+ A
Sbjct: 24269 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVAR--TTLKVTKLKTGTEYQFRIFA 24326

Query: 1744  QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
             +N  G S ALES+PIV +     P           I  +S+ I W     NGGSP+I Y 
Sbjct: 24327 ENRYGQSFALESDPIVAQYPYKEPG-PPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYH 24385

Query: 1804  VEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             +E K+     W             + Q L     Y+FR+YA N +G      + +     
Sbjct: 24386 LERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 24445

Query: 1861  KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
                 PP  P   +V  +    +TL+WT+P  +GGS IT YI+E + +    W K      
Sbjct: 24446 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 24502

Query: 1921  SVHEHCIENIKEKDEIIFRISAENTVG-VSLPTES 1954
                +  +  + E     FR+ A+N  G +S P++S
Sbjct: 24503 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS 24537



 Score =  256 bits (628), Expect = 4e-66
 Identities = 263/1191 (22%), Positives = 485/1191 (40%), Gaps = 95/1191 (7%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            ++ + P F+ KL+  +   G++V  EC+V G     + WF+    I      Q  + + N
Sbjct: 7663 DRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE-N 7721

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            V TL +  + P D G +TCVA N AG    +  L V+ P S   +  +V           
Sbjct: 7722 VCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSV----------- 7770

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
              ++L G+  TF+       V  G+           P   + W     E+VP E+ ++++
Sbjct: 7771 --EVLPGMSLTFTS------VIRGT-----------PPFKVKWFKGSRELVPGESCNISL 7811

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
            E     + + L++  V+  + G Y+ +  N  G AS    L +    KEP   ++ L   
Sbjct: 7812 ED----FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV----KEPATFVKRLADF 7863

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGV 802
             V  G  ++L A   G P  +++W K+   +      S   T   TIL+     ++D   
Sbjct: 7864 SVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQ 7923

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y+   EN  G     A+++V        EPP FI   + +         L  +V   P  
Sbjct: 7924 YSCLIENEAGQDICEALVSV-------LEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI 7976

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             I+WY+ +  +  +      F      LVI  VD   D G+Y C A NS G  +  A + 
Sbjct: 7977 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHS-DVGEYSCKADNSVGAVASSAVLV 8035

Query: 923  IDVEKVT--FVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978
            I   K+   F + L+  +ET  G  V  EC+   S  +   WY +   +    + +    
Sbjct: 8036 IKERKLPPFFARKLKDVHET-LGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 8094

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE-TIPEF--IRKLQ-DFEVKE 1030
                           +G   C   +      +S  L++ E  +P F  ++ +  D  + E
Sbjct: 8095 HNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGE 8154

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC- 1089
                   V   +    + W +D   I+P  N Y      +   L +      D G+Y+C 
Sbjct: 8155 SGTFKCHV-TGTAPIKITWAKDNREIRPGGN-YKMTLVENTATLTVLKVGKGDAGQYTCY 8212

Query: 1090 ---ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT-FEIELTKGDAL-VRWFKDGS 1144
               I   +SC+A + V E PP  I +L+  ++ K ++ T +E ++     + V W+KD +
Sbjct: 8213 ASNIAGKDSCSAHLGVQE-PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 8271

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTL 1200
            EIQ S+  +++       L++++  ++D+G+Y+CE     G++  +  L V+EP I    
Sbjct: 8272 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPI--FR 8329

Query: 1201 RLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
            + P  I      D +L  E+       V+WYK K  +   +K+ ++S+    ++ I    
Sbjct: 8330 KKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVD 8389

Query: 1260 EDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
              D  EY C    D  S T +    ++ PP+ V    +     G +V L    +     +
Sbjct: 8390 AADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPIS 8449

Query: 1319 DEWIVN-SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              W  +  +I+++  +   S     A+L   +VE  +AG Y  +++N+ G  +    +++
Sbjct: 8450 VVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV 8509

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT 1436
            L+  +   KP  +++ +   + C  E    G   +   +  + +E+ +     +    K 
Sbjct: 8510 LEPATIVEKPESIKVTTG--DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 8567

Query: 1437 Q-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
                I N+  + S  +     N V     + + +        +   P+  + LK      
Sbjct: 8568 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV-----SDRTVPPSFTRKLKETNGLS 8622

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCI 1551
               + + C   G P   V+W+ +G ++ + +       +N                Y CI
Sbjct: 8623 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 8682

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            A N  G  E S  + +++ P   +   D       G     T++++G PP  V W+K  +
Sbjct: 8683 ATNMAGSDECSAPLTVREPPSF-VQKPD-PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSS 8740

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            +L      N++ ++  + + + ++  S S +YT   SN AG +S    L +
Sbjct: 8741 ELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 8791



 Score =  256 bits (627), Expect = 5e-66
 Identities = 198/757 (26%), Positives = 326/757 (43%), Gaps = 35/757 (4%)

Query: 1218  VEIPDETLDVTWYK--KKSVIEDTEKFTLISDVK---KRTLIIRKCTEDDQCEYTCVLLD 1272
             +E+ ++  D  WY+    + I +TE FT + D+K   K +  +         EY+  + +
Sbjct: 30305 LEMQEKDTD-QWYRVHTNATIRNTE-FT-VPDLKMGQKYSFRVAAVNVKGMSEYSESIAE 30361

Query: 1273  AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
              +   ++++  +E      D ++   I+ G+ + L+V     P P   W  + + I    
Sbjct: 30362 IEPVERIEIPDLELAD---DLKKTVTIRAGASLRLMVSVSGRPPPVITW--SKQGIDLAS 30416

Query: 1333  HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
                       + L + KV   DAG Y +  EN  G     + V + D P P     + E+
Sbjct: 30417 RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEV 30476

Query: 1393  DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRF 1451
                S+ I W+ P   G + +  Y+VE +E     + +V    +KT   I  L   + Y F
Sbjct: 30477 SRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYF 30536

Query: 1452  RAYAVNEVDISDASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
             R    N   I +  ET++   V    +   K++   V K    +  E       + + G 
Sbjct: 30537 RVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGY 30596

Query: 1508  VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCV 1564
             V +          K+ T K T                   ++  A N+ G  E   T   
Sbjct: 30597 VLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYL---FRIRAQNEKGVSEPRETVTA 30653

Query: 1565  VGIQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             V +Q     P I +S    K  H   G    +   I G PPP   W+  G+KL   +   
Sbjct: 30654 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 30713

Query: 1621  ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
             + T  K + + I+E     + +YT+E  N  GT+S  + + + DKP  P GP+ + EI  
Sbjct: 30714 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 30773

Query: 1681  ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMF 1739
              S+TI W+PP  DGG  L+ Y +E+ +     W+ V++ V R   T+   +L E  EY+F
Sbjct: 30774 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTR--STFKFTRLTEGNEYVF 30831

Query: 1740  RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             RV A N  G    L+SE I  ++++ +P           +  + + +TW+P E +GGS +
Sbjct: 30832 RVAATNRFGIGSYLQSEVIECRSSIRIPG-PPETLQIFDVSRDGMTLTWYPPEDDGGSQV 30890

Query: 1800  IDYKVEIKQ-EGKKWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDK 1856
               Y VE K+    +W           R +   L+    Y+ R+ A N  G+  P      
Sbjct: 30891 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30950

Query: 1857  ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
             I     + PP +P+N  V+++T  SV+L W+ PE  GGS +T Y+IE + V    WTK  
Sbjct: 30951 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCN 31010

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
             T    + E+ + ++ +  E  FR+ A N  G   P E
Sbjct: 31011 TTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAE 31047



 Score =  252 bits (616), Expect = 1e-64
 Identities = 252/1068 (23%), Positives = 432/1068 (40%), Gaps = 60/1068 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P    +K     V  G    LEC++   PE  + W   G+ +   +    +  + +    
Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI---- 6685

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            S L+I +V++   GTYT    N  G++S   V+ + +    PP     LK+     G S 
Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDV-SDRAVPPSFTRRLKNTGGVLGASC 6744

Query: 753  ILSAQVVGNPRPTITWC-KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810
            IL  +V G+   ++ W  +  K V     ++    +  T+ L      D G YT  A N 
Sbjct: 6745 ILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 6804

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G  E  AV+TV+EP       P F+   + + V     +   + +   P   + W+R  
Sbjct: 6805 AGSDECRAVLTVQEP-------PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 6857

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +   +     F+    EL + N+D    SG+Y CV SN+AG++S   R+ +  E   F
Sbjct: 6858 RELVKGDRCNIYFEDTVAELELFNIDIS-QSGEYTCVVSNNAGQASCTTRLFVK-EPAAF 6915

Query: 931  VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            +K L   +  E GK++ILE   + T  +S  W  +   I+  +   I+   +        
Sbjct: 6916 LKRLS-DHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILN 6974

Query: 989  XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSET 1044
                D G   C ++++   +    LV     P F+ +L+  E    D   L+ ++  +  
Sbjct: 6975 STKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPE 7034

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV- 1103
              V W +    ++P   +Y      ++  L     +++D GEY+C   +   TA    V 
Sbjct: 7035 ITVSWYKGDTKLRPTP-EYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 7093

Query: 1104 -----ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID 1157
                 +LPP    +L++ +   G   T    L     + V W++DG  ++   ++Q +  
Sbjct: 7094 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFV 7153

Query: 1158 GKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN--FTLRLPEFILVPAN 1211
                 LKI   DL  +G+YSC     +G +  +A LT  EP  +  F ++ P  I V A 
Sbjct: 7154 DNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDVIAG 7212

Query: 1212 TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              A     +   + + +TW K    I     +T+        L I K  + D  +YTC  
Sbjct: 7213 ESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 7272

Query: 1271 LD--AKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVN-SK 1326
             +   K     ++ V E PPK V      ++ K+G  + L       P+    W  N S+
Sbjct: 7273 TNDVGKDMCSAQLSVKE-PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSE 7331

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
            + +  K+    I+S  A LTI +    D+G Y     N  G A     +T+   P    K
Sbjct: 7332 LHESWKYNMSFINSV-ALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQK 7390

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
            P+ +     S  I   E   T    +++     Q  ++ ++        T   I NL+ +
Sbjct: 7391 PSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEAS 7450

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
                +   A NEV  SD    +  +K       + P   K L + +T   + +EL  I  
Sbjct: 7451 DVGEYHCKATNEVG-SDTCSCSVKFK-------EPPRFVKKLSDTSTLIGDAVELRAIVE 7502

Query: 1507 GVPQPKVTWYRD-GKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G     V W +D G+ ++ ++ T     +N                Y C   ND G  E 
Sbjct: 7503 GFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMREC 7562

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            S V+ + +   I    E +      G+ + +  V+ G P     W+K+G +L  D +++I
Sbjct: 7563 SAVLTVLEPARIIEKPEPMTV--TTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHI 7620

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            T   K + ++I   + S    Y+ E  N+ G S+  V++ V D+   P
Sbjct: 7621 TFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPP 7668



 Score =  251 bits (615), Expect = 1e-64
 Identities = 271/1159 (23%), Positives = 474/1159 (40%), Gaps = 79/1159 (6%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            + E  PPTF  +PK+     G      C +   P  +  W   G  + P  N  ++   +
Sbjct: 4472 VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN 4531

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             H    +L+++N+     G Y+  A N+ G A +     I   +    + +EP++S I  
Sbjct: 4532 KH----ILELSNLTIQDRGVYSCKASNKFG-ADICQAELIIIDKPHFIKELEPVQSAI-- 4584

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTL 805
              + V L  QV  + + T+TW K+ + +      K   +    T+  P  K+KD G Y  
Sbjct: 4585 -NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVC 4643

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSI 864
             A N  G +  SA +TV        EPP F+ +     +   G + +L  ++  +PV  +
Sbjct: 4644 TASNEAGSSSCSATVTVR-------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV 4696

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TW++NN+ +S S T+   F      L IT+V  E DSG Y C A N  G  S    + I 
Sbjct: 4697 TWFKNNKELSESNTVRMYFVNSEAILDITDVKVE-DSGSYSCEAVNDVGSDSCSTEIVIK 4755

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXX 982
             E  +F+K L+ + +   G   +L+C+ S T      W+ +KK+I       +  +    
Sbjct: 4756 -EPPSFIKTLEPA-DIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV 4813

Query: 983  XXXXXXXXXXDVGVIKCIVKDQ--ETSTML--VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
                      DVG  +C+V ++  +   M   ++KE  P F++K+ D          L+ 
Sbjct: 4814 CLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEP-PTFVKKVDDLIALGGQTVTLQA 4872

Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095
             +  SE   V W +  E+I+ +  K        +  L I +  +   G+Y+C+  +E+  
Sbjct: 4873 AVRGSEPISVTWMKGQEVIR-EDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS 4931

Query: 1096 -CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153
              +    +V+ P +II R +  +V  G+ AT E  +     L  +W+KDG  +  S   +
Sbjct: 4932 QTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4991

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSIN--FTLRLPEFIL 1207
            ++      +LK Y  +L D+G+Y    S EVG+S C    TV +  I   FT  L     
Sbjct: 4992 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDS 5051

Query: 1208 VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            V  N    L  +I     + V+W+K    I  ++++ +       +L I +   +D   +
Sbjct: 5052 V-VNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNF 5110

Query: 1267 TCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            TC   ++  S       +V+ PP  V       +  GS V L   +Q        W   +
Sbjct: 5111 TCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 5170

Query: 1326 KII---KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            K +     C  TK +++S   SL +  V+ +D+G Y  ++ N  G  +   N+ + +  +
Sbjct: 5171 KELVSGGSCYITKEALES---SLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT 5227

Query: 1383 PPGK---PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT 1438
               K     +L+   ++   C    + TG   I I +    +EI  +    +  +  T  
Sbjct: 5228 FVEKLEPSQLLKKGDATQLAC----KVTGTPPIKITWFANDREIKESSKHRMSFVESTAV 5283

Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
              + ++    S  +   A NE      S       ++KE    SP   K  K I      
Sbjct: 5284 LRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV----IVKE----SPYFTKEFKPIEVLKEY 5335

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXXXXXXXXXXXXXXXYKCIAF 1553
            D+ L     G P  ++TW++D   L++ +   T+  ++                Y+C   
Sbjct: 5336 DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVT 5395

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N+ G    S  V +++ P      E        G      A ++G  P  V W K+ +++
Sbjct: 5396 NEVGSSICSARVTLREPPSFIKKIESTSSLR--GGTAAFQATLKGSLPITVTWLKDSDEI 5453

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
              D    +T +   + + +  ++  H  KY  +A N AG       L V +  +  E  V
Sbjct: 5454 TEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAV 5513

Query: 1674 IMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWIKVADVDR-DVETYCIQKL 1731
             +     +  T++ K     G  E+T K+  +  E       K++  D   +      + 
Sbjct: 5514 SIDVTQGDPATLQVK---FSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEK 5570

Query: 1732 NENCEYMFRVIAQNPVGFS 1750
             ++ EY F V  QN VG S
Sbjct: 5571 KDSGEYTFEV--QNDVGRS 5587



 Score =  248 bits (608), Expect = 1e-63
 Identities = 245/1035 (23%), Positives = 430/1035 (41%), Gaps = 63/1035 (6%)

Query: 664  DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
            ++ W F+ + +  DE        D + Y  V+   N +  Q G Y   A+N  G+ +   
Sbjct: 4317 EVNWYFENKLVPSDEKFKCL--QDQNTYTLVIDKVNTEDHQ-GEYVCEALNDSGKTATSA 4373

Query: 724  VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPT 780
              K+   ++  P +   ++ + V  G     + ++   P     W K  + +        
Sbjct: 4374 --KLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI 4431

Query: 781  KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ 840
            +S     S+ IL+ + V D G YT KA N  G    +A +TV E     A PP F++R +
Sbjct: 4432 RSSKYISSLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTE-----AYPPTFLSRPK 4485

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV-ITNVDSEI 899
             +T       K +  VT  PV    W ++   +SPS     + D EN  ++ ++N+  + 
Sbjct: 4486 SLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKIS-DAENKHILELSNLTIQ- 4543

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
            D G Y C ASN  G     A + I ++K  F+K L+   ++   K V LECQ      V+
Sbjct: 4544 DRGVYSCKASNKFGADICQAELII-IDKPHFIKELEP-VQSAINKKVHLECQVDEDRKVT 4601

Query: 958  TKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
              W  + +++  G D++ I  E +            D G   C   ++  S+      T+
Sbjct: 4602 VTWSKDGQKLPPGKDYK-ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660

Query: 1017 ---PEFIRKLQ-DFEVKEKDVAILEVEIN-SETADVVWERDG-EIIKPKKNKYDFEKRGH 1070
               P F++K+   + +   + A L  ++  S    V W ++  E+ +    +  F     
Sbjct: 4661 REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 4720

Query: 1071 IRKLYIRNTSVHDEGEYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATF 1126
            I  L I +  V D G YSC  + D   +SC+ E+ + E PP  I  L+   + +G  A  
Sbjct: 4721 I--LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE-PPSFIKTLEPADIVRGTNALL 4777

Query: 1127 EIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
            + E++  G   + WFKD  +I+ S   +L        L+I+  +  D GEY C    EVG
Sbjct: 4778 QCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 4837

Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
               C A   ++EP   F  ++ + I +   T          E + VTW K + VI +  K
Sbjct: 4838 KCGCMATHLLKEPP-TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGK 4896

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300
              +        LII         +YTC+   +A S T +   +V+ P KI++     ++ 
Sbjct: 4897 IKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVT 4956

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
             G   TL       P+   +W  + + +   K  + S  +  A L     E  D+G Y  
Sbjct: 4957 AGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTF 5016

Query: 1361 RLENNCGHADVEMNVTILDKPSPP--GKPNILEIDSSSINICWDEPENTGNSTI-IYYVV 1417
             + N  G +  E   T+LD+   P   KP +  +DS     C  + +  G+  + + +  
Sbjct: 5017 EISNEVGSSSCETTFTVLDRDIAPFFTKP-LRNVDSVVNGTCRLDCKIAGSLPMRVSWFK 5075

Query: 1418 EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            + +EI  ++   +  +  T +  I  +  N +  F   A N V   D+S       +++E
Sbjct: 5076 DGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL----IVQE 5131

Query: 1477 TKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
                   V KP  K++   P   + L   F G     + W++  K+L +  + Y  +   
Sbjct: 5132 PP---SFVTKPGSKDVL--PGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEAL 5186

Query: 1536 XXXXXX----XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C   N  G VE S  + +++ P   +   +  Q  K GD   
Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-PATFVEKLEPSQLLKKGDATQ 5245

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +   + G PP ++ W+ N  +++   ++ ++  E T+V+R+ ++    S +Y  EA N A
Sbjct: 5246 LACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEA 5305

Query: 1652 GTSSVEVTLKVYDKP 1666
            G+      + V + P
Sbjct: 5306 GSDHCSSIVIVKESP 5320



 Score =  248 bits (606), Expect = 2e-63
 Identities = 190/706 (26%), Positives = 301/706 (42%), Gaps = 43/706 (6%)

Query: 1300  KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK---HTKPS-----IDSKSASLTIKKVE 1351
             K GS + +    +  P P   W  + K  K  K   H  P          S+ + I + +
Sbjct: 16750 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 16809

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              +  G Y +  +N  G       V ++D P PP    + +I   S  + W  P++ G   
Sbjct: 16810 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDR 16869

Query: 1412  IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE- 1469
             I  YV+E + ID   W  V  +   T   + +L +   Y FR  A N   I    ET + 
Sbjct: 16870 IKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQR 16929

Query: 1470  ------YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
                    Y      K++   + K   +++ +P ++   + +   + +  + W   G K +
Sbjct: 16930 TTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC-LAWDPTGTKKE 16988

Query: 1524  TAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNE 1578
               +   +                    ++  A N  G  + S  VG    Q+P +  S  
Sbjct: 16989 AWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI- 17047

Query: 1579  DIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE-------YNITTKEKTSV 1629
             D+K+  +V  G    + A I+G+P P + W+K   K  ++KE        N    + T  
Sbjct: 17048 DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCT 17107

Query: 1630  IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
             + I + +RS +  YTI A N  GT+S E+ L V  +P  P GP+    +S + +T+ W P
Sbjct: 17108 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFP 17167

Query: 1690  PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
             P DDGG ++T Y IEK E +   W+ V+   ++  TY I KL E  EY+FR++AQN  G 
Sbjct: 17168 PKDDGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHEYVFRIMAQNKYGI 17226

Query: 1750  SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808
              E L+SEP   +    VP           +   S+ + W   E +GGSP+  Y +E+K  
Sbjct: 17227 GEPLDSEPETARNLFSVPG-APDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDT 17285

Query: 1809  EGKKWK------XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
               K+WK                ++  L   + YQFR+YA N  G        D  T    
Sbjct: 17286 TSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 17345

Query: 1863  LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
             + PP  P    V++ T  S  L+W+ P  +GGS +T YI+E+K    + W K        
Sbjct: 17346 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 17404

Query: 1923  HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
              +  +  +KE     FR+SA N  G+  P E   V +E    + SP
Sbjct: 17405 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDV-IEMKDRLVSP 17449



 Score =  247 bits (605), Expect = 2e-63
 Identities = 188/685 (27%), Positives = 304/685 (44%), Gaps = 31/685 (4%)

Query: 1300  KRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             K G DV +L+ ++  P P   W  + K +    +++  + DS S  LTI +V   D G Y
Sbjct: 28211 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKY 28269

Query: 1359  KLRLENNCGHADVE-MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
              L +EN  G      ++V +LD P+   K  +  +   ++ + WD P   G S II YV+
Sbjct: 28270 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 28329

Query: 1418  EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             E ++     W  V +  + T   + +L   + + FR  A NE+ I +  ETTE    +K 
Sbjct: 28330 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE---PVKA 28386

Query: 1477  TKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKT-AKATYENRX 1533
              ++ +P  +  +K+ +T+ +  +  T     GG    +    R GK  +T + A      
Sbjct: 28387 AEVPAPIRDLSMKD-STKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 28445

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ------KHKVG 1587
                           ++  A N+ G  +   +  I  K +I     D+          ++G
Sbjct: 28446 EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG 28505

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
                 +    +G P P + W K+G  L+  +    +  E    + IK  K+ H  KYT+  
Sbjct: 28506 HNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVIL 28565

Query: 1648  SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
              N     +V +T+     PSKP+GP+   EI  +SV + W  P D+GG E+T Y+IEK E
Sbjct: 28566 DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRE 28625

Query: 1708  PDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
                  W  V + V R   T+ +  L ++ EY FRV A+N  G S+ L S  IV K    +
Sbjct: 28626 TSQTNWKMVCSSVAR--TTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRI 28683

Query: 1767  PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXX--XXXX 1823
             P           + ++ + +TW     +GGS +  + VE K+     W+           
Sbjct: 28684 PG-PPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE 28742

Query: 1824  ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVSESTSRSV 1882
              R   L     YQFR+YA N  G S P +   K T+    + PP  P +++  + T  ++
Sbjct: 28743 YRATGLVEGLDYQFRVYAENSAGLSSP-SDPSKFTLAVSPVDPPGTP-DYI--DVTRETI 28798

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
             TLKW  P  +GGS I  Y IE K    + W +      S  ++ +  +   D   FRI A
Sbjct: 28799 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 28857

Query: 1943  ENTVG-VSLPTESQSVRLEKHATVP 1966
              N VG +S P++S  + + +   VP
Sbjct: 28858 RNAVGTISPPSQSSGIIMTRDENVP 28882



 Score =  245 bits (600), Expect = 9e-63
 Identities = 188/708 (26%), Positives = 303/708 (42%), Gaps = 35/708 (4%)

Query: 1287  PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             PP+I    D  +   ++  + + L V  +  P+P  +W     I+      +  + S   
Sbjct: 26031 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFT 26088

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
              L I  V   D+G Y L LENN G     +NV +LD PS P    I E+   S+ + W+ 
Sbjct: 26089 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 26148

Query: 1404  PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
             P   G + I  Y+VE +E     + ++  N TKT   I+NL+   SY FR  A NE  I 
Sbjct: 26149 PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 26208

Query: 1463  DASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
               +ETTE  KV    +   ++    V +    I  E  E    + I G V + +    + 
Sbjct: 26209 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT---KG 26265

Query: 1519  GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVG--IQQKPV 1572
              +K  T   T                   ++  A N+ G  +       V+   I+ KP 
Sbjct: 26266 SEKWSTC--TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 26323

Query: 1573  ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
             + +       K +  ++  +    +G P   V W K+G  L+     N+++ +  + + I
Sbjct: 26324 VELPFHTFNVKAR--EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 26381

Query: 1633  KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             KE  +     Y +  SN+AG+ +V +T+ V D+P  P GP+ + E+S +S+TI W PP  
Sbjct: 26382 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEY 26440

Query: 1693  DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
             DGG +++ Y +EK E  +  W  V+       +  I +L    EY FRV A+N  G S  
Sbjct: 26441 DGGCQISNYIVEKKETTSTTWHIVSQAVART-SIKIVRLTTGSEYQFRVCAENRYGKSSY 26499

Query: 1753  LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK- 1811
              ES  +V +     P               ++ +TW     +GGS +I Y +E K+    
Sbjct: 26500 SESSAVVAEYPFSPPGPPGTPKVVHA-TKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 26558

Query: 1812  KWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
              W             ++  L     Y++R+YA N  G      S + +       PP QP
Sbjct: 26559 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 26618

Query: 1870  RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
                 V+  T +SV+LKW++P  +GG+ IT YI+E + +    W K            +  
Sbjct: 26619 E---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 26675

Query: 1930  IKEKDEIIFRISAENTV-GVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
             + E     FR+ A N    VS P+ES    + K      PP   ++++
Sbjct: 26676 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDV--EPPRVMMDVK 26721



 Score =  245 bits (599), Expect = 1e-62
 Identities = 274/1209 (22%), Positives = 485/1209 (40%), Gaps = 96/1209 (7%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            VEK +     +   +  EC V G P  ++ W +    I PS+ F M +++ NVA+  I+ 
Sbjct: 6071 VEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN-NVASFRIQS 6129

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
            V  +D+G +T   +N   F SS+ +  +                           + + I
Sbjct: 6130 VMKQDSGQYTFKVEN--DFGSSSCDAYLRV-------------------------LDQNI 6162

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F+KK        GS I +EC++         W   G+EI    + S       H   
Sbjct: 6163 PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEI----STSAKYRLVCHERS 6218

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGES 751
              L++ N++      YT    N  G+ +   +L +K    EPP  +++P +   +    +
Sbjct: 6219 VSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK----EPPSFLVKPGRQQAIPDS-T 6273

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809
            V   A + G P   I W K++  + + P    G   S + L    V     G YT    N
Sbjct: 6274 VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR 868
              G    + ++ V        EPP F+ + +   + + G + +L  ++  +P   + W+R
Sbjct: 6334 DVGSDSCTTMLLV-------TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFR 6386

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            N   +  S+     F      + + N+ +E DSGD+ C A N AG +S   +V +    V
Sbjct: 6387 NEHELPASDKYRMTFIDSVAVIQMNNLSTE-DSGDFICEAQNPAGSTSCSTKVIVKEPPV 6445

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
                      ET +   V LEC+ S T      WY +K+++      +I  +        
Sbjct: 6446 --FSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 6503

Query: 987  XXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042
                  D+G   C  +++   +T    V  +  P F+ KL    V   + A L+  I  +
Sbjct: 6504 LNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGA 6563

Query: 1043 ETADVVWERDGE-IIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE- 1099
            +   V W ++ E +I+  +N +  F +  ++  L        + G+Y C ++++    E 
Sbjct: 6564 QPIFVQWLKEKEEVIRESENIRITFVE--NVATLQFAKAEPANAGKYICQIKNDGGMEEN 6621

Query: 1100 -VTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
              T++ L P +I        V  G   T E ++     L V W+KDG  +  S   + + 
Sbjct: 6622 MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF 6681

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFILVPA 1210
              K   L+I   +  DAG Y+ +V    G S CTA++ V + ++  +FT RL     V  
Sbjct: 6682 YNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGV-L 6740

Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                 L  ++   + + V W+ +K+ I    K+         TL +      D   YTCV
Sbjct: 6741 GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 6800

Query: 1270 LLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
              +   + + + V  V+ PP  V       +  G +VT     +  P     W   ++ +
Sbjct: 6801 AANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAREL 6860

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
             K        +   A L +  ++ + +G Y   + NN G A     + + +  +   + +
Sbjct: 6861 VKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLS 6920

Query: 1389 ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
               ++     I   E   TG   I + +  +   I T+E  ++  +T  +T I  +  NS
Sbjct: 6921 DHSVEPGKSIIL--ESTYTGTLPISVTWKKDGFNITTSEKCNI--VTTEKTCILEI-LNS 6975

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            + R       E++ ++A    +    +  T ++ P     L+ +     + + L C   G
Sbjct: 6976 TKRDAGQYSCEIE-NEAGR--DVCGALVST-LEPPYFVTELEPLEAAVGDSVSLQCQVAG 7031

Query: 1508 VPQPKVTWYRDGKKLKTAKA--TY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
             P+  V+WY+   KL+      TY   N                Y C A N  G   +  
Sbjct: 7032 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 7091

Query: 1564 VVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
            V  IQ++   P      +DI+Q   VG    +T  + G  P +V WY++G  L +D+   
Sbjct: 7092 VFRIQERQLPPSFARQLKDIEQT--VGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 7149

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP---EGPVIMRE 1677
             +  +  + ++I +   SHS +Y+  ASN  GT+S    L   +    P     PV +  
Sbjct: 7150 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDV 7209

Query: 1678 ISRESVTIE 1686
            I+ ES   E
Sbjct: 7210 IAGESADFE 7218



 Score =  244 bits (598), Expect = 2e-62
 Identities = 242/1086 (22%), Positives = 448/1086 (41%), Gaps = 65/1086 (5%)

Query: 633  PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F KK + ++ V +      EC++   PE  + W     EI       ++    +   
Sbjct: 8231 PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSV--- 8287

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             +VL++ N+     G YT  A N  G AS    LK+K    EPP   +    +   +G  
Sbjct: 8288 -AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK----EPPIFRKKPHPIETLKGAD 8342

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V L  ++ G P   ++W K+ + +   K     S+    SI IL      D G Y  KA 
Sbjct: 8343 VHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA-DIGEYQCKAT 8401

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G       I ++ P       P F+ +  +I+      ++L   +      S+ W++
Sbjct: 8402 NDVGSDTCVGSIALKAP-------PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK 8454

Query: 869  NN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            +  EI+  S+ I  ++  ENI  +  +     ++G Y C   N AG     A +++ +E 
Sbjct: 8455 DKGEIVRESDNIWISYS-ENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV-LEP 8512

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             T V+   +S +   G T  LEC  + T  +STKW+ + KE++  +  +I    +     
Sbjct: 8513 ATIVEK-PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLK 8571

Query: 986  XXXXXXXDVGVIKCIV-----KDQETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVE 1039
                   D GV    V     KD  T+++ V   T+P  F RKL++         ++E +
Sbjct: 8572 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECK 8631

Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094
            +  S    V W  +G  I   + KY      +   L +      D G+Y+CI  +    +
Sbjct: 8632 VYGSPPISVSWFHEGNEISSGR-KYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSD 8690

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHI 1152
             C+A +TV E PP  + +     V  G   TF   + KG     V WFK  SE+   +  
Sbjct: 8691 ECSAPLTVRE-PPSFVQKPDPMDVLTGTNVTFT-SIVKGTPPFSVSWFKGSSELVPGDRC 8748

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             ++++    +L+++D D   +GEY+C    E G + CT  L ++ P+  F  RL ++ + 
Sbjct: 8749 NVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA-KFVKRLNDYSIE 8807

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
                            + VTW K    +  +++  + +  K   L I   T +D  +Y C
Sbjct: 8808 KGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNC 8867

Query: 1269 VLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
             + +A  K +   ++ ++E PP  V      ++  G   +L       P+    W     
Sbjct: 8868 YIENASGKDSCSAQILILE-PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDT 8926

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             ++     K    +  A+L   +V+  D+G Y  + EN+ G       +T+ ++  PP  
Sbjct: 8927 KLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSF 8986

Query: 1387 PNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
               L     ++   + +D   +      + +  + + +  +  +    +  T T +   K
Sbjct: 8987 SRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT-LNIFK 9045

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
            T+ S   +        I  AS +     ++ E K   P  +  L  +     E  +  C 
Sbjct: 9046 TDRSLAGQYSCTATNPIGSASSSARL--ILTEGK-NPPFFDIRLAPVDAVVGESADFECH 9102

Query: 1505 FGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G    KV+W +D +++++    + +Y EN                Y C A N+ G+  
Sbjct: 9103 VTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDS 9162

Query: 1561 TSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             +  + I+++ +     + + +  +   G+ + +   + G  P  V WYKN  +++    
Sbjct: 9163 CTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSN 9222

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
              IT K  T V+++++   + +  YT + SN AG++    ++ V  +P KP  PV  + +
Sbjct: 9223 CEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI-VIKEPKKP--PVFDQHL 9279

Query: 1679 SRESVT 1684
            +  +V+
Sbjct: 9280 TPVTVS 9285



 Score =  244 bits (596), Expect = 3e-62
 Identities = 272/1208 (22%), Positives = 492/1208 (40%), Gaps = 98/1208 (8%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            +EK  P     G+    EC V G P     WF+    +       + + +  VA+L I  
Sbjct: 7575 IEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFIN-KVASLKIPC 7633

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
                D G ++   KN+ G ++ T        +S H S+  V                   
Sbjct: 7634 AEMSDKGLYSFEVKNSVGKSNCT--------VSVHVSDRIV------------------- 7666

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F +K K      G+ ++LECR+       + W   G EIV       +   ++   C
Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENV---C 7723

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L ++ ++    G YT VA N  G      VL +    +EPP   +   S+ V  G S+
Sbjct: 7724 T-LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV----QEPPSFEQTPDSVEVLPGMSL 7778

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
              ++ + G P   + W K ++ +    + +      +T L+  +V+  + G Y+    N 
Sbjct: 7779 TFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTND 7838

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G A  +  + V+EP         F+ R  + +V+    I L A  T  P  S++W ++ 
Sbjct: 7839 AGSASCTTHLFVKEPA-------TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDE 7891

Query: 871  EIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             +IS SE  +IT       +E++ + ++   D   Y C+  N AG+    A V++ +E  
Sbjct: 7892 YLISQSERCSITMTEKSTILEILESTIE---DYAQYSCLIENEAGQDICEALVSV-LEPP 7947

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             F++ L+   E   G+   L+C+   T  +   WY    ++      ++  +        
Sbjct: 7948 YFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 8006

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040
                  DVG   C   +      +S +LV+KE    P F RKL+D           E  I
Sbjct: 8007 NKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRI 8066

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            N SE   V W +DG ++K   N        ++  L I  T     G+Y+C   +   TA 
Sbjct: 8067 NGSEPLQVSWYKDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTAS 8125

Query: 1100 ------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151
                  ++  E+PP    +  +  +  G   TF+  +T G A ++  W KD  EI+   +
Sbjct: 8126 SSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVT-GTAPIKITWAKDNREIRPGGN 8184

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRL-PEFI 1206
             ++T+      L +      DAG+Y+C      G   C+A L V+EP   F  +L P  I
Sbjct: 8185 YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPP-RFIKKLEPSRI 8243

Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            +       Y         + V WYK ++ I+++ KF +        L +   + +D  +Y
Sbjct: 8244 VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDY 8303

Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            TC   +A  +      + V+ PP            +G+DV L  + Q  P  +  W  + 
Sbjct: 8304 TCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDK 8363

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
            + ++  K  K   ++   S+ I  V+  D G Y+ +  N+ G      ++ +   P    
Sbjct: 8364 RELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVK 8423

Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISV-KNITKTQTSIQ 1441
            K  +I  +    + +     E     +++++  + + +  ++  WIS  +NI   Q S  
Sbjct: 8424 KLSDISTVVGKEVQL-QTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFS-- 8480

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
             ++  ++ ++     N+  + +   T     V++   I    VEKP ++I     +   L
Sbjct: 8481 RVEPANAGKYTCQIKNDAGMQECFAT---LSVLEPATI----VEKP-ESIKVTTGDTCTL 8532

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHG 1557
             C   G P+    W++DGK+L +    K ++ N+                Y     N  G
Sbjct: 8533 ECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            +   +  + +  + V       +K+ + + G   ++   + G PP  V W+  GN++ + 
Sbjct: 8593 KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSG 8652

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
            ++Y  T  + T  + +  L+ S S  YT  A+N AG+      L V + PS  + P  M 
Sbjct: 8653 RKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMD 8712

Query: 1677 EISRESVT 1684
             ++  +VT
Sbjct: 8713 VLTGTNVT 8720



 Score =  243 bits (595), Expect = 4e-62
 Identities = 244/1062 (22%), Positives = 433/1062 (40%), Gaps = 60/1062 (5%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L+C++       ++W   G+EI   +   +A         + L+I  V     G +T  A
Sbjct: 5059 LDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT----ASLEIIRVDMNDAGNFTCRA 5114

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             N  G       L ++    EPP  +    S  V  G +V L +   G+   TI W K N
Sbjct: 5115 TNSVGSKDSSGALIVQ----EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 5170

Query: 773  KPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            K + +  +   +     S   L   K  D G YT K  N  G  E SA + V+EP     
Sbjct: 5171 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT--- 5227

Query: 831  EPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
                F+ + +   + +KG   +L  +VT  P   ITW+ N+  I  S     +F      
Sbjct: 5228 ----FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAV 5283

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL- 948
            L +T+V  E DSG+Y C A N AG S H + + I  E   F K  +     +E   ++L 
Sbjct: 5284 LRLTDVGIE-DSGEYMCEAQNEAG-SDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLA 5341

Query: 949  ECQTSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007
            E   +      W+ +   + SG  ++  IQ+              D G  +C V ++  S
Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQD-HLVSLQILKFVAADAGEYQCRVTNEVGS 5400

Query: 1008 TMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKN-K 1062
            ++   + T+   P FI+K++         A  +  +  S    V W +D + I    N +
Sbjct: 5401 SICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIR 5460

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKV 1118
              FE   ++  LY+    V  +G+Y C  ++++    C+A ++V E P  I     +  V
Sbjct: 5461 MTFEN--NVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-PATITEEAVSIDV 5517

Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
             +G+ AT +++ +   +   +WFKDG E+   +  ++++      LKI   +  D+GEY+
Sbjct: 5518 TQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 5577

Query: 1178 CEV----GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
             EV    G S C A + V +  I  +FT +L +   +  +      +      + + W+K
Sbjct: 5578 FEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFK 5637

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI 1290
                I  +EK+          L I +    D   YTC   +     +    + V+ PP  
Sbjct: 5638 DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYF 5697

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
            V+  +   +   + V L            +W  ++K +          D  S SL +   
Sbjct: 5698 VEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAA 5757

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
            + TD+G Y  +L N+ G A  +  + + + P    KP+ + +  +  +  + E + TG  
Sbjct: 5758 KATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTF-ECQITGTP 5816

Query: 1411 TI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             I + + ++  EI   +   +  I    T  I   +  +S  +   A N+   +  S   
Sbjct: 5817 KIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 5876

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA- 1527
            +    +KE     PT  + LK +      D+EL C   G P  +VTW ++ ++++++K  
Sbjct: 5877 K----VKEP----PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKY 5928

Query: 1528 TYENRXXXXXXXXXX---XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584
            T  +R                  Y+CI  N+ G    S  V +++ P      E+     
Sbjct: 5929 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVL 5988

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K    +  T  + G PP  + W K+   L+ D    I+  +  + ++I+ +   HS +YT
Sbjct: 5989 KSSATFQST--VAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYT 6046

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             +A N +G       L V +     E    +    ++ +T+E
Sbjct: 6047 CQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLE 6088



 Score =  243 bits (594), Expect = 5e-62
 Identities = 176/609 (28%), Positives = 276/609 (45%), Gaps = 30/609 (4%)

Query: 1379  DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436
             DKPS PG+  IL I   S+ + W++PE  G   I+ Y VEY++   + W   + + I   
Sbjct: 31356 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 31415

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             Q +I  L   + Y FR +A NE  +S    T    K  K T  ++P + K +K++TT+  
Sbjct: 31416 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVTTKLG 31474

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIA 1552
             E  +L+C   G P P + WYR GK+L   +  K + + R                Y CIA
Sbjct: 31475 EAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIA 31534

Query: 1553  FNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNG 1610
              N+ GEVETS  + +Q  P        +K+K+   VG    +  +  G P P + W+   
Sbjct: 31535 TNEVGEVETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQ 31593

Query: 1611  NKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
               L+N +   I   E  + + +K ++R +H+ KY ++ SN  GT    + +++ DKP KP
Sbjct: 31594 KLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKP 31653

Query: 1670  EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
              GP+++  + + S  I WKPP DDGG  +T Y +EK E       ++      V T  I 
Sbjct: 31654 TGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIV 31713

Query: 1730  KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
              L EN  Y FRV AQN  G S+ LE S  ++IK+  + P           +  +S  + W
Sbjct: 31714 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG-APGKPTITAVTKDSCVVAW 31772

Query: 1789  FPSEKNGGSPIIDYKVEIKQEGK--KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNE 1844
              P   +GG+ I +Y +E K+E K  KW              ++ L     Y+FR+   N 
Sbjct: 31773 KPPASDGGAKIRNYYLE-KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENL 31831

Query: 1845  IGTSLPYTSDDKITIGKTLTPPSQP------RNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
              G S      + IT  K+  P   P      RN  V   ++ ++  K T        PI 
Sbjct: 31832 GGESEWSEISEPIT-PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT----GHPKPIV 31886

Query: 1899  NYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
              +  + K +       +I    G  H+  I ++ + D  ++++ A N  G    T S  V
Sbjct: 31887 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 31946

Query: 1958  RLEKHATVP 1966
              +     +P
Sbjct: 31947 EVPAKIHLP 31955



 Score =  242 bits (593), Expect = 6e-62
 Identities = 215/796 (27%), Positives = 348/796 (43%), Gaps = 54/796 (6%)

Query: 1195  SINFTLRLPEFILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
             +I  +L+LP F          L +EIP       +++W K    ++ T +  +       
Sbjct: 25236 TIQPSLKLP-FNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 25294

Query: 1252  TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
              L I++  +DD  +YT    ++  T    L V V+E P   V      R    S   +++
Sbjct: 25295 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG---PVRFDEVSADFVVI 25351

Query: 1310  DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL---TIKKVENTDAGIYKLRL--EN 1364
              ++  P       +++ I++K   T  +    SA++   TIK  +      Y+ R+  EN
Sbjct: 25352 SWEP-PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAEN 25410

Query: 1365  NCGH-ADVEMNVTILD----KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
               G  A ++    I+     +P PPG P +  I    + + W EP N G + II Y +E 
Sbjct: 25411 RYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 25470

Query: 1420  QEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +E ++  W+ +    I  T+     L     Y F+  A N V I   S+ +E +  +   
Sbjct: 25471 KEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF--VARD 25528

Query: 1478  KIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPKVTWYRDGKKL----KTAKATYEN 1531
                 P   +P   + T  N  ++       GG    K+T Y   KK     +  KA++ N
Sbjct: 25529 PCDPPG--RPEAIVITRNNVTLKWKKPAYDGG---SKITGYIVEKKDLPDGRWMKASFTN 25583

Query: 1532  RXXXXXXXXXXXXXXXY--KCIAFNDHGEV-ETSCVVG-IQQKPVITISNEDIKQKHK-- 1585
                             Y  + IA N  G   E S   G I  +  I   N  +  K+K  
Sbjct: 25584 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 25643

Query: 1586  ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNI-TTKEKTSVIRIKELKRSH 1639
                  G+ +++ A I G P P+V+W K+G +LE       I +T +KT+++ +K+  R+ 
Sbjct: 25644 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV-VKDCIRTD 25702

Query: 1640  SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
               +Y ++ SN  GT S+ +T+KV D+P  PEGP+ +  ++ E   + W PPL DGG  ++
Sbjct: 25703 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 25762

Query: 1700  KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
              Y IEK E     W +V+  +     Y + KL    EY+FRV+A N  G  E LES P+ 
Sbjct: 25763 HYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 25821

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XX 1816
                    P           I  +S+ +TW     +GG+ I  Y +E + +EG +W     
Sbjct: 25822 ACNPYK-PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 25880

Query: 1817  XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     R+  L+   +Y+FR+ A N  G   P            L PP  P N  V++
Sbjct: 25881 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTD 25940

Query: 1877  STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDE 1935
             ++  SV+L W++P  +GG+P+  Y++E K      WT      G    +  +  +KE  E
Sbjct: 25941 TSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 26000

Query: 1936  IIFRISAENTVGVSLP 1951
               FRI A N+ GV  P
Sbjct: 26001 YNFRICAINSEGVGEP 26016



 Score =  240 bits (588), Expect = 3e-61
 Identities = 245/1068 (22%), Positives = 429/1068 (40%), Gaps = 65/1068 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F +KP++Q V+  + + L+  +       I W    +E+      SV  +       
Sbjct: 5694 PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTS---- 5749

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751
            + L++   K    GTY     N  G A+    L +K    EPPQ I+ P   +++R G+S
Sbjct: 5750 TSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK----EPPQFIKKPSPVLVLRNGQS 5805

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI--LKPKKVKDEGVYTLKAEN 809
                 Q+ G P+  ++W  +   + A+          +    +   +V++ G Y  +A N
Sbjct: 5806 TTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARN 5865

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G A  S  + V+EP       P FI   + + V +   ++L   VT  P   +TW +N
Sbjct: 5866 DAGTASCSIELKVKEP-------PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKN 5918

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            N  I  S+  T         L IT  D   D+G+Y+C+ SN  G  S   RV +  E  +
Sbjct: 5919 NREIRSSKKYTLTDRVSVFNLHITKCDPS-DTGEYQCIVSNEGGSCSCSTRVALK-EPPS 5976

Query: 930  FVKHLQKSYET-EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            F+K ++ +    +   T       S  +S  W  + + +   D+  I             
Sbjct: 5977 FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRS 6036

Query: 989  XXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSE 1043
                  G   C  K++         L+V+E   + + K +  +V EKD   LE V   + 
Sbjct: 6037 VDNGHSGRYTCQAKNESGVERCYAFLLVQEPA-QIVEKAKSVDVTEKDPMTLECVVAGTP 6095

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAE 1099
               V W +DG+ I P +  +      ++    I++    D G+Y+  + ++    SC A 
Sbjct: 6096 ELKVKWLKDGKQIVPSRY-FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154

Query: 1100 VTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
            + V++  +PP    +L       G+    E +++    +  +WFKDG EI  S   +L  
Sbjct: 6155 LRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC 6214

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
              +   L++ + +L+D   Y+C+V    G+  C+ ILTV+EP  +F ++      +P +T
Sbjct: 6215 HERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP-SFLVKPGRQQAIPDST 6273

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLL 1271
              +  +        + W+K    +    K  +  +     L +         +YTC V  
Sbjct: 6274 VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333

Query: 1272 DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIK 1329
            D  S +   + +V  PPK V   E    +K G    L       P+    W  N  ++  
Sbjct: 6334 DVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPA 6393

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
              K+    IDS  A + +  +   D+G +    +N  G       V + + P     P I
Sbjct: 6394 SDKYRMTFIDSV-AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPI 6452

Query: 1390 LE-IDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTN 1446
            +E + ++ +++ C  E   T    +++Y  + Q   + ++ I+ KN   T   I N+ T+
Sbjct: 6453 VETLKNAEVSLEC--ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNF-HTSIHILNVDTS 6509

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
                +   A NEV  SD    T   K       + P     L ++T    E  EL     
Sbjct: 6510 DIGEYHCKAQNEVG-SDTCVCTVKLK-------EPPRFVSKLNSLTVVAGEPAELQASIE 6561

Query: 1507 GVPQPKVTWYRDGKKL----KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G     V W ++ +++    +  + T+ EN                Y C   ND G  E 
Sbjct: 6562 GAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEEN 6621

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + + +  VI      +     VG+   +   + G P   V WYK+G  L + +++  
Sbjct: 6622 MATLMVLEPAVIVEKAGPMTVT--VGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKF 6679

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            +   K S +RI  ++R  +  YT +  N  G SS    + V D+   P
Sbjct: 6680 SFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPP 6727



 Score =  239 bits (585), Expect = 6e-61
 Identities = 195/695 (28%), Positives = 293/695 (42%), Gaps = 36/695 (5%)

Query: 1280  KVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             K E    PP+I    D  +   I+    + L V  +  P P  +W  +          K 
Sbjct: 22777 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE----SLDKA 22832

Query: 1337  SIDSKSAS--LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
             SI+S S+   L +  V   D+G Y L +EN+ G     +NV +LD P PP    + E+  
Sbjct: 22833 SIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTK 22892

Query: 1395  SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRA 1453
             +S+ + WD P   G S I  Y+VE +E     + +V  N  KT   +  L+   SY FR 
Sbjct: 22893 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22952

Query: 1454  YAVNEVDISDASETTEYYKVIKET----KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
              A NE  I   +ET E  K  +      KI    V +   +++ E  E    + I G + 
Sbjct: 22953 LAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIV 23012

Query: 1510  QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSCVVGI 1567
             + +           T K T                   ++  A N+ G  +     V  I
Sbjct: 23013 EMQTKGSDKWATCATVKVT-----EATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVI 23067

Query: 1568  QQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
              +  VI  + + +     V  G++  V     G P P V W+K+   L+     N  + E
Sbjct: 23068 AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTE 23127

Query: 1626  KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
               S++ IK+  R     Y ++ +N+AG +   + + V DKP  P GPV M E++ +S+T+
Sbjct: 23128 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITL 23187

Query: 1686  EWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
              W PP  DGG  +  Y +EK +     W I  A V R     C  +L   CEY FR+ A+
Sbjct: 23188 SWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKAC--RLKTGCEYQFRIAAE 23245

Query: 1745  NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
             N  G S  L SEP V +    VP              +S+ + W     +GGS +I Y +
Sbjct: 23246 NRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS-SRDSMEVQWNEPISDGGSRVIGYHL 23304

Query: 1805  EIKQEGK-KWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             E K+     W           + +   L     Y+FR+ A N +G   P    +      
Sbjct: 23305 ERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 23364

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
                PP +P   +V   T  SVTL+W +P  +GGS IT YI+E K +    W K  +    
Sbjct: 23365 PCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK-ASFTNI 23420

Query: 1922  VHEHC-IENIKEKDEIIFRISAENTVGV-SLPTES 1954
             +  H  +  + E     FR+ A N  GV S P+ES
Sbjct: 23421 IDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 23455



 Score =  238 bits (583), Expect = 1e-60
 Identities = 195/762 (25%), Positives = 325/762 (42%), Gaps = 47/762 (6%)

Query: 1219  EIPDETLDVTWYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             +I D + D  W +  +  +   K FT+ S  + +    R C ++       +   A+   
Sbjct: 19465 KIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ----VGIGRPAELKE 19520

Query: 1278  KLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKC 1331
              +K + +  PP+I D +   R    ++ G  + L    +  P P   W  +    +++K 
Sbjct: 19521 AIKPKEILEPPEI-DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRK- 19578

Query: 1332  KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
                +  +    A L I      D+G Y L L N  G   V +NV +LD P P     + +
Sbjct: 19579 --GQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSD 19636

Query: 1392  IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYR 1450
             +  +S ++ W  PEN G S + +Y+VE +E D   W +V   + KT   + NL   + Y 
Sbjct: 19637 VTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYY 19696

Query: 1451  FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FG 1506
             FR  AVNE      ++  +   V+    +  P   + L+ +T        L  +     G
Sbjct: 19697 FRVTAVNEYGPGVPTDVPK--PVLASDPLSEPDPPRKLE-VTEMTKNSATLAWLPPLRDG 19753

Query: 1507  GVP-QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHG-----E 1558
             G      +T YR+ ++       Y                  YK    A N  G     E
Sbjct: 19754 GAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPRE 19813

Query: 1559  VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
              E       Q  P   +  E I  K   G +  + A + G P P   W K  +++     
Sbjct: 19814 AEGVYEAKEQLLPPKILMPEQITIK--AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSH 19871

Query: 1619  YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
               +   + +S++ IK++ R  S  Y++ A N++GT + ++ + V D P  P+ P  + +I
Sbjct: 19872 LAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDI 19931

Query: 1679  SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI-KVADVDRDVETYC-IQKLNENCE 1736
               ++ ++ W  PL+DGG  +T Y +EK +     W+  +A V    +T C + KL    E
Sbjct: 19932 DADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV---TKTSCRVGKLIPGQE 19988

Query: 1737  YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
             Y+FRV A+N  G SE L S  +V +    VPS          ++ + +++ W   + +GG
Sbjct: 19989 YIFRVRAENRFGISEPLTSPKMVAQFPFGVPS-EPKNARVTKVNKDCIFVAWDRPDSDGG 20047

Query: 1797  SPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTS 1853
             SPII Y +E K+     W                 +     Y FRIYA N+ G+S P   
Sbjct: 20048 SPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 20107

Query: 1854  DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
              + +T    + PP +P    V++ST   V+L W  P+ +GGS I  Y +E   + G  W 
Sbjct: 20108 TEYVTARMPVDPPGKPEVIDVTKST---VSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 20164

Query: 1914  KIVTVGGSV--HEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
             +  T    +   E+    ++EK +  FR  A   V +S P+E
Sbjct: 20165 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSE 20206



 Score =  238 bits (583), Expect = 1e-60
 Identities = 199/754 (26%), Positives = 323/754 (42%), Gaps = 35/754 (4%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
             +TW K    ++ T +  +   +   TL I++  +DD  +Y   + +        +E+V  
Sbjct: 24188 ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTL 24247

Query: 1287  PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL- 1345
               K    +   +    S  ++ + +   P       + + I++K   T    D  SA++ 
Sbjct: 24248 D-KPDPPKGPVKFDDVSAESITLSWNP-PLYTGGCQITNYIVQKRDTTTTVWDVVSATVA 24305

Query: 1346  -TIKKVENTDAGI-YKLRL--ENNCGHA-DVEMNVTILD----KPSPPGKPNILEIDSSS 1396
              T  KV     G  Y+ R+  EN  G +  +E +  +      +P PPG P    I   S
Sbjct: 24306 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDS 24365

Query: 1397  INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAY 1454
             + I W EP N G S +I Y +E +E ++  W  V    I  TQ   QNL+    Y FR Y
Sbjct: 24366 MVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVY 24425

Query: 1455  AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG-VPQPKV 1513
             A N V +  AS+ +E Y  +       P   +P+     E           GG +    +
Sbjct: 24426 AENIVGVGKASKNSECY--VARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYI 24483

Query: 1514  TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEV-ETSCVVG-IQQ 1569
                RD    +  KA++ N                Y  + IA N  G + + S   G I  
Sbjct: 24484 VEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITA 24543

Query: 1570  KPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             K  + +    +  K +       G+ + + A + G P P + W +   ++E      I  
Sbjct: 24544 KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 24603

Query: 1624  KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
              +  +++ +K+  R    +Y + ASN AG+ S  V +KV D+P  PEGPV +  ++ E  
Sbjct: 24604 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC 24663

Query: 1684  TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             ++ W PPL DGG +++ Y +EK E     W  VA  +    +  + KL E  EY+FR++A
Sbjct: 24664 SLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS-EVVTNSLKVTKLLEGNEYVFRIMA 24722

Query: 1744  QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
              N  G  E LES P+++K    +P           I  +S+ + W   + +GGS II Y 
Sbjct: 24723 VNKYGVGEPLESAPVLMKNPFVLPG-PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 24781

Query: 1804  VEIK-QEGKKW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             VE + + G +W             R+  L+ +  Y+FR+ A N  G   P  +       
Sbjct: 24782 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 24841

Query: 1861  KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--V 1918
               +  P  P N  + ++T  S+TL W +P  +GGS I  Y++E      + W +IVT   
Sbjct: 24842 DPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEW-QIVTPQT 24900

Query: 1919  GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             G  V    I  + E  E   R+ A N VG+   T
Sbjct: 24901 GLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT 24934



 Score =  236 bits (578), Expect = 4e-60
 Identities = 240/1090 (22%), Positives = 432/1090 (39%), Gaps = 63/1090 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P    +KP+   V  G+   LEC +   PE    W   G E+  D    +   + +    
Sbjct: 7571 PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKV---- 7626

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + LKI   +   +G Y+    N  G+++  + + + +    PP  I  LK +    G SV
Sbjct: 7627 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV-SDRIVPPSFIRKLKDVNAILGASV 7685

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
            +L  +V G+   ++ W ++   + + P      + ++  L    ++  D G+YT  A N 
Sbjct: 7686 VLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANV 7745

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G  E SAV+TV+EP       P F      + V    ++   + +   P   + W++ +
Sbjct: 7746 AGSDECSAVLTVQEP-------PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS 7798

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              + P E+   + +    EL +  V   ++SGDY C+ +N AG +S    + +  E  TF
Sbjct: 7799 RELVPGESCNISLEDFVTELELFEVQP-LESGDYSCLVTNDAGSASCTTHLFVK-EPATF 7856

Query: 931  VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            VK L   +  E G  ++LE   + T  +S  W  ++  IS  +   I    +        
Sbjct: 7857 VKRLA-DFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 7915

Query: 989  XXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SET 1044
                D     C++++   Q+    LV     P FI  L+  E    + A L+ +++ +  
Sbjct: 7916 STIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPE 7975

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEV 1100
              + W ++   ++     Y  + + ++  L I      D GEYSC   D S     ++ V
Sbjct: 7976 IRISWYKEHTKLRSAP-AYKMQFKNNVASLVINKVDHSDVGEYSC-KADNSVGAVASSAV 8033

Query: 1101 TVVE---LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
             V++   LPP    +L++     G    FE  +   + L V W+KDG  ++   ++Q + 
Sbjct: 8034 LVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF 8093

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA------ILTVEEPSINFTLRLPEFILVPA 1210
                  L+I   D    G+Y+C   N   TA      IL+  E    F L+     L   
Sbjct: 8094 VHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALG 8153

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
             +  +         + +TW K    I     + +       TL + K  + D  +YTC  
Sbjct: 8154 ESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 8213

Query: 1271 LDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKII 1328
             +          + V+ PP+ +      RI +  + T         P+    W  +   I
Sbjct: 8214 SNIAGKDSCSAHLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI 8273

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
            ++    + S     A L +  +   D+G Y     N  G A    ++ + + P    KP+
Sbjct: 8274 QESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPH 8333

Query: 1389 ILE-IDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
             +E +  + +++ C  E + T    + +Y  + +     ++  +     T   I N+   
Sbjct: 8334 PIETLKGADVHLEC--ELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA 8391

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
                ++  A N+V     S+T      +K      P   K L +I+T   ++++L     
Sbjct: 8392 DIGEYQCKATNDV----GSDTCVGSIALKAP----PRFVKKLSDISTVVGKEVQLQTTIE 8443

Query: 1507 GVPQPKVTWYRD-GKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G     V W++D G+ ++ +   +    EN                Y C   ND G  E 
Sbjct: 8444 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 8503

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + + +   I    E IK     GD   +   + G P     W+K+G +L +D +Y I
Sbjct: 8504 FATLSVLEPATIVEKPESIKVT--TGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKI 8561

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE---I 1678
            +   K S ++I  +  S S  Y+ E  N  G  S   +L+V D+   P     ++E   +
Sbjct: 8562 SFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGL 8621

Query: 1679 SRESVTIEWK 1688
            S  SV +E K
Sbjct: 8622 SGSSVVMECK 8631



 Score =  235 bits (574), Expect = 1e-59
 Identities = 255/1071 (23%), Positives = 432/1071 (40%), Gaps = 75/1071 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F KK +       S    +  +   P   I WL   + +  D+N+ ++    +    
Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV---- 6029

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L+I +V     G YT  A N  G       L ++    EP Q++E  KS+ V + + +
Sbjct: 6030 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ----EPAQIVEKAKSVDVTEKDPM 6085

Query: 753  ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L   V G P   + W K+ K   P +      + +  S  I    K +D G YT K EN
Sbjct: 6086 TLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMK-QDSGQYTFKVEN 6144

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G +   A + V    ++N  PP F  +  ++      +I +  +V+ +   S  W+++
Sbjct: 6145 DFGSSSCDAYLRV---LDQNI-PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKD 6200

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + IS S          ++ L + N++ E D+ +Y C  SN AG  +    +T+      
Sbjct: 6201 GKEISTSAKYRLVCHERSVSLEVNNLELE-DTANYTCKVSNVAGDDACSGILTVKEPPSF 6259

Query: 930  FVKHLQKSY---ETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             VK  ++      T E K ++   + +     KW+ +  E+       I  EG       
Sbjct: 6260 LVKPGRQQAIPDSTVEFKAIL---KGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 6316

Query: 987  XXXXXXDVGVIKCIVKDQETS----TMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEI- 1040
                    G   C V +   S    TML+V E  P+F++KL+  + VK  D + LE +I 
Sbjct: 6317 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-PKFVKKLEASKIVKAGDSSRLECKIA 6375

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SC 1096
             S    VVW R+   + P  +KY       +  + + N S  D G++ C  ++     SC
Sbjct: 6376 GSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSC 6434

Query: 1097 TAEVTVVELP-----PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
            + +V V E P     P I+  L+N +V+       E EL+      V W+KD  +++ S 
Sbjct: 6435 STKVIVKEPPVFSSFPPIVETLKNAEVS------LECELSGTPPFEVVWYKDKRQLRSSK 6488

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI 1206
              ++        + I + D  D GEY C    EVG+  C   + ++EP   F  +L    
Sbjct: 6489 KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP-RFVSKLNSLT 6547

Query: 1207 LVPANTDAYLTVEIPD-ETLDVTWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            +V A   A L   I   + + V W K+K  VI ++E   +       TL   K    +  
Sbjct: 6548 VV-AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAG 6606

Query: 1265 EYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            +Y C +  D      +   +V  P  IV+      +  G   TL       P+ + EW  
Sbjct: 6607 KYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYK 6666

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            + K++   +  K S  +K +SL I  VE  DAG Y  +++NN G +     V + D+  P
Sbjct: 6667 DGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP 6726

Query: 1384 PGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQ 1441
            P     L+     +   C  E +  G+S I   V  + E   T+ +S  K  T    ++ 
Sbjct: 6727 PSFTRRLKNTGGVLGASCILECKVAGSSPI--SVAWFHE--KTKIVSGAKYQTTFSDNVC 6782

Query: 1442 NLKTNS--SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
             L+ NS  S     Y     +++ + E          T  + P+  K  + +   P +++
Sbjct: 6783 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVL-----TVQEPPSFVKEPEPLEVLPGKNV 6837

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENR-XXXXXXXXXXXXXXXYKCIAFND 1555
              T +  G P  KV W+R  ++L         +E+                 Y C+  N+
Sbjct: 6838 TFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNN 6897

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             G  + SC   +  K              + G   ++ +   G  P  V W K+G  +  
Sbjct: 6898 AG--QASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6955

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             ++ NI T EKT ++ I    +  + +Y+ E  N AG       +   + P
Sbjct: 6956 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 7006



 Score =  233 bits (569), Expect = 5e-59
 Identities = 254/1091 (23%), Positives = 436/1091 (39%), Gaps = 71/1091 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            IPP+F+KK K     +GS I LEC +       I W    +EI   E    +     H  
Sbjct: 5600 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFS----FHDN 5655

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L+I+ ++    GTYT  A N+ G       L +    KEPP  +E  +S  V     
Sbjct: 5656 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV----KEPPYFVEKPQSQDVNPNTR 5711

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAEN 809
            V L A V G    TI W K+NK + +   +S    DT +   L   K  D G Y  +  N
Sbjct: 5712 VQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSN 5771

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR 868
              G A + A + V+       EPP FI +   + V   G +     ++T  P   ++WY 
Sbjct: 5772 DVGTATSKATLFVK-------EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL 5824

Query: 869  N-NEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            + NEI +  +      DG    ++    V+   +SG Y C A N AG +S    + +  E
Sbjct: 5825 DGNEITAIQKHGISFIDGLATFQISGARVE---NSGTYVCEARNDAGTASCSIELKVK-E 5880

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              TF++ L K  E  +   V LEC+ + T      W  N +EI       +         
Sbjct: 5881 PPTFIREL-KPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNL 5939

Query: 985  XXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                    D G  +CIV ++      ST + +KE  P FI+K+++     K  A  +  +
Sbjct: 5940 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP-PSFIKKIENTTTVLKSSATFQSTV 5998

Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---- 1095
              S    + W +D +I+    N Y       +  L IR+      G Y+C  ++ES    
Sbjct: 5999 AGSPPISITWLKDDQILDEDDNVY-ISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVER 6057

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
            C A + V E P +I+ + ++  V + +  T E  +     L V+W KDG +I  S +  +
Sbjct: 6058 CYAFLLVQE-PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSM 6116

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFILV 1208
            + +      +I      D+G+Y+ +V    G+S C A L V + +I  +FT +L +   V
Sbjct: 6117 SFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV 6176

Query: 1209 PANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
               +  ++  ++     +   W+K    I  + K+ L+   +  +L +     +D   YT
Sbjct: 6177 -LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 6235

Query: 1268 CVLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            C + +         +  V+ PP  +      +    S V      +  P    +W  +  
Sbjct: 6236 CKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDV 6295

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             +         ++  ++ L +  V+ +  G Y   + N+ G       + + + P    K
Sbjct: 6296 ELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKK 6355

Query: 1387 ---PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQN 1442
                 I++   SS   C  +   +    ++++  E+ E+  ++   +  I       + N
Sbjct: 6356 LEASKIVKAGDSSRLEC--KIAGSPEIRVVWFRNEH-ELPASDKYRMTFIDSVAVIQMNN 6412

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
            L T  S  F   A N    +  S       ++KE  + S     P+  + T  N ++ L 
Sbjct: 6413 LSTEDSGDFICEAQNPAGSTSCSTKV----IVKEPPVFSSF--PPI--VETLKNAEVSLE 6464

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            C   G P  +V WY+D ++L+++K    A+                   Y C A N+ G 
Sbjct: 6465 CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS 6524

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
                C V +++ P        +      G+   + A IEG  P  V W K   ++  + E
Sbjct: 6525 DTCVCTVKLKEPPRFVSKLNSLTV--VAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE 6582

Query: 1619 -YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
               IT  E  + ++  + + +++ KY  +  N  G      TL V +     E    M  
Sbjct: 6583 NIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTV 6642

Query: 1678 ISRESVTIEWK 1688
               E+ T+E K
Sbjct: 6643 TVGETCTLECK 6653



 Score =  232 bits (568), Expect = 7e-59
 Identities = 185/693 (26%), Positives = 284/693 (40%), Gaps = 30/693 (4%)

Query: 1292  DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
             +  R   ++ G  + + V  +  P P   W  ++  +K   + + +       L I +  
Sbjct: 21708 ELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENT--ESFTLLIIPECN 21765

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
               D G + + +EN  G     +NV +LD P P       +I   S+ + WD P   G S 
Sbjct: 21766 RYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSR 21825

Query: 1412  IIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             I  Y+VE +E     +  +     K    +  L     Y FR  A NE  I + +ETTE 
Sbjct: 21826 ITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE- 21884

Query: 1471  YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-----RDGKKLKTA 1525
                +K ++  SP     + +IT              G    K+T Y     R G    T 
Sbjct: 21885 --PVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDG--GSKITGYVIEAQRKGSDQWTH 21940

Query: 1526  KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISNEDIKQ 1582
               T +                 ++ +A N  G     E+  V+  +Q  +  +    I Q
Sbjct: 21941 ITTVKG-LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 21999

Query: 1583  K---HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
             K    K GD   V   + G P P V W K    L+  +  N  T   ++++ I E  RS 
Sbjct: 22000 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSD 22059

Query: 1640  SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             S  Y + A N  G     +T++V+D P  P GP+   E+S + VT  W PP +DGG+ ++
Sbjct: 22060 SGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPIS 22119

Query: 1700  KYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
              Y +E  + D+  W+++A  V R   TY   +L    EY FRV AQN  G    + S  I
Sbjct: 22120 NYVVEMRQTDSTTWVELATTVIR--TTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACI 22177

Query: 1759  VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXX 1817
             V      VP           +  +S+ I+W     +GGSPI+ Y VE K+  G  W+   
Sbjct: 22178 VANYPFKVPG-PPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVS 22236

Query: 1818  XXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                      +   L+    Y+FR+ A N  G S P    + +     + PP +P   V  
Sbjct: 22237 KALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKP---VPL 22293

Query: 1876  ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
               T  +VTLKW +PE  GG  IT+YI+E + +    W K        +E  +  + E   
Sbjct: 22294 NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 22353

Query: 1936  IIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
               FR+ A+N  G   P    S  +     V +P
Sbjct: 22354 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAP 22386



 Score =  232 bits (568), Expect = 7e-59
 Identities = 197/760 (25%), Positives = 319/760 (41%), Gaps = 45/760 (5%)

Query: 1247  DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
             + K R   I    + D CE T  +   K+  +L    ++      ++++ + ++ G+ + 
Sbjct: 29250 EYKFRVSAINGAGKGDSCEVTGTI---KAVDRLTAPELDID---ANFKQTHVVRAGASIR 29303

Query: 1307  LLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
             L + YQ  P P   W    ++  ++   HT  S     ++LT++     DAG Y L +EN
Sbjct: 29304 LFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSF----STLTVENCNRNDAGKYTLTVEN 29359

Query: 1365  NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
             N G   +   V +LD P PPG     ++   S  + WD P   G + I +YVVE +E   
Sbjct: 29360 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 29419

Query: 1425  TEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
               W +  +  T+    + +L     Y FR  AVNE  +    E  E  + I  T  + P 
Sbjct: 29420 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG---EPYEMPEPIVAT--EQPA 29474

Query: 1484  VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXX 1539
               + L  + T  +  +            ++T Y    + K +    +A +  +       
Sbjct: 29475 PPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVER 29534

Query: 1540  XXXXXXXXYKCIAFNDHG-----EVETSCVVGIQQ-KPVIT---ISNEDIKQKHKVGDEW 1590
                     ++  A ND G     E  +S ++   Q +P      I+N+ I  K   G  +
Sbjct: 29535 LVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCK--AGSPF 29592

Query: 1591  LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
              +   I G P P+V W     +L+     +ITT +  + + +K+  R  S +Y +   NT
Sbjct: 29593 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 29652

Query: 1651  AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
             AG  +  VT+ V  +P    GP+ +  +S ES  + W  P D GG E+T Y +EK E   
Sbjct: 29653 AGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGT 29712

Query: 1711  NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
               W  V    +  +   +  L +  EY FRV ++N  G S+ LES PI+ +    VP   
Sbjct: 29713 TAWQLVNSSVKRTQIK-VTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPF-VPPSA 29770

Query: 1771  XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXXARIQ 1827
                     +   ++ I W     +GGS II Y VE K+     W  +          ++ 
Sbjct: 29771 PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVT 29830

Query: 1828  KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
              L     YQFR YA N  G S    +   I     +  P +P    V++ T  +V+L W+
Sbjct: 29831 GLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWS 29887

Query: 1888  EPESNGGSPITNYIIEFKTVK---GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
              P  +GGS +  YIIE K V       W K      S +   +  + E D   FR+ A+N
Sbjct: 29888 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 29947

Query: 1945  TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
               GV +   S+S          +PP A L+ R+ G  + +
Sbjct: 29948 AAGV-ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTI 29986



 Score =  231 bits (565), Expect = 2e-58
 Identities = 221/892 (24%), Positives = 366/892 (41%), Gaps = 44/892 (4%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVK 1249
             VE P +   ++  + I+V A     +  +I    L V +W K    IE+  +  +IS   
Sbjct: 26711 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN 26770

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP-PKIVDYEREYRIKRGSDVT 1306
                L ++ C   D  +Y   L +   T  + V  +V++ P P     E          ++
Sbjct: 26771 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 26830

Query: 1307  LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
                  +      D +IV  +       T    + +  S  + K+   +  I+++   N  
Sbjct: 26831 WGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKY 26890

Query: 1367  GHADVEMNVTI--LDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
             G  +   +V I  LD    PSPP    I  +   S+ +CW  PE+ G S I  Y++E +E
Sbjct: 26891 GVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERRE 26950

Query: 1422  IDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
              ++  W+ V  K +   +     L+    Y +R YA N   +S  SET+   +      +
Sbjct: 26951 KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL 27010

Query: 1480  QSPTVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTW-YR-----DGK-KLKTAKAT-YE 1530
              SP  +  + +          +  +F GG P    T  Y+     D K  +++ + T Y 
Sbjct: 27011 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 27070

Query: 1531  NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDE 1589
                               K  A +     +       +++P+  I +E  K    K G  
Sbjct: 27071 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 27130

Query: 1590  WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
             + +T    G P P V+W K    L   + Y  TT  +TS + I+   R+ S KYT+   N
Sbjct: 27131 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTS-LTIENANRNDSGKYTLTIQN 27188

Query: 1650  TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
                 +S+ + +KV D P  P   + ++++++ES  + W  P +DGG  +  Y IEK E  
Sbjct: 27189 VLSAASLTLVVKVLDTPGPPTN-ITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREAS 27247

Query: 1710  NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
                W+ V +    + +Y +  L E   Y FRV  +N  G     E++  V  T    P  
Sbjct: 27248 KKAWVSVTNNCNRL-SYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 27306

Query: 1770  XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK 1828
                      I  +SV +TW   E +GGS I+ Y VE  ++G+K W            +  
Sbjct: 27307 KLGVTS---ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSG 27363

Query: 1829  LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-QPRNFVVSESTSRS-VTLKW 1886
             L  N+ Y FR++A N+ G S P      + I + L PP    +NF       R+   LK 
Sbjct: 27364 LRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKV 27423

Query: 1887  TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK---DEIIFRISAE 1943
               P S  G P+    +    V  K+  +  T      E+   N+KE    D   + I+A 
Sbjct: 27424 DIPIS--GKPLPKVTLSRDGVPLKATMRFNT--EITAENLTINLKESVTADAGRYEITAA 27479

Query: 1944  NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
             N+ G +       V L++    P PPT P+ I  +    V   W  P++DGG+ +  Y +
Sbjct: 27480 NSSGTT-KAFINIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL 27534

Query: 2004  AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
               R+ +  +W EV      T+   +  L+    Y  RI A N  G+S+ ++S
Sbjct: 27535 LKRETSTAVWTEVSATVARTM-MKVMKLTTGEEYQFRIKAENRFGISDHIDS 27585



 Score =  230 bits (563), Expect = 3e-58
 Identities = 211/770 (27%), Positives = 325/770 (42%), Gaps = 50/770 (6%)

Query: 1216  LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             L V++P     T  VTW+K    ++ T +    S      L I+    +D   Y   L +
Sbjct: 23092 LKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTN 23151

Query: 1273  A--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
             +  ++   L V V++ P       +   +   S +TL       P+ +    +N+ I++K
Sbjct: 23152 SAGEAIETLNVIVLDKPGPPTGPVKMDEVTADS-ITLS---WGPPKYDGGSSINNYIVEK 23207

Query: 1331  ---CKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHAD-VEMNVTILDKP--- 1381
                   T   + +  A  TIK         Y+ R+  EN  G +  +    T+   P   
Sbjct: 23208 RDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 23267

Query: 1382  -SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
               PPG P +      S+ + W+EP + G S +I Y +E +E ++  W+ +    I +T+ 
Sbjct: 23268 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKF 23327

Query: 1439  SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
                 L+    Y FR  A N V I   S+ +E Y  +       P   +P   I T  +  
Sbjct: 23328 KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY--VARDPCDPPG--RPEAIIVTRNSVT 23383

Query: 1499  IELT--CIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXY--KC 1550
             ++       GG    K+T Y   KK     +  KA++ N                Y  + 
Sbjct: 23384 LQWKKPTYDGG---SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRV 23440

Query: 1551  IAFNDHGEV-ETSCVVG-IQQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPP 1602
             IA N  G   E S   G I  +  +      +  K+K       G+ + V A I G P P
Sbjct: 23441 IARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIP 23500

Query: 1603  EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
              + W K   +L N     I + +  + + +K+  R  S  Y ++A N AG  SV V +KV
Sbjct: 23501 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 23560

Query: 1663  YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
              D+P  PEGPV++  ++ E  T+ WKPPL DGG ++  Y +E+ E     W  V D +  
Sbjct: 23561 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW-TVVDANVQ 23619

Query: 1723  VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
               +  + KL E  EY FR++A N  G  E LESEP+V K    VP           +  +
Sbjct: 23620 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPD-APKAPEVTTVTKD 23678

Query: 1783  SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRI 1839
             S+ + W     +GGS I+ Y +E + +EG +W           R++   +  N  Y+FR+
Sbjct: 23679 SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRV 23738

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
              A N  G S P            +  P  P N  V + T  SV L W++P  +GG  I  
Sbjct: 23739 SAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQG 23798

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGV 1948
             YI+E   V    WT      G    +  +E + EK E  FRI A N  GV
Sbjct: 23799 YIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 23848



 Score =  230 bits (563), Expect = 3e-58
 Identities = 170/673 (25%), Positives = 288/673 (42%), Gaps = 33/673 (4%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             ++ G    + + ++  P P   W             +  ++     L+I   +  DAG Y
Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNY--TQLSIDNCDRNDAGKY 25020

Query: 1359  KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
              L+LEN+ G     + V +LD P PP    + E+   S  + W+ P   G + +  YV++
Sbjct: 25021 ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID 25080

Query: 1419  YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
              +E     + +V +  +KT   ++NL   + Y FR  A NE  +    ET +  K  +  
Sbjct: 25081 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPP 25140

Query: 1478  ----KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVTWYRDGKKLKTAKATYEN 1531
                 K+    V +   ++  E  E    + + G V   QPK T     K    A++   N
Sbjct: 25141 SPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT----EKWSIVAESKVCN 25196

Query: 1532  RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-----KV 1586
                             ++  A+N+ G+ +   V+G+            +K        + 
Sbjct: 25197 ---AVVTGLSSGQEYQFRVKAYNEKGKSDPR-VLGVPVIAKDLTIQPSLKLPFNTYSIQA 25252

Query: 1587  GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
             G++  +   + G P P + W K+G  L+     N+     ++V+ IKE  +    KYT+ 
Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 25312

Query: 1647  ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
             A+N+AGT++  +++ V +KP  P GPV   E+S + V I W+PP   GG +++ Y +EK 
Sbjct: 25313 ATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 25372

Query: 1707  EPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
             +     W  V A V R   T  I KL    EY FR+ A+N  G S  L+S+ ++++    
Sbjct: 25373 DTTTTTWHMVSATVAR--TTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 25430

Query: 1766  VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA 1824
              P           I  + + + W     +GG+ II Y +E K++    W           
Sbjct: 25431 EPG-PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDT 25489

Query: 1825  RIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
             + +   ++    Y+F++ A N +G   P    +         PP +P   V+   T  +V
Sbjct: 25490 KFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI---TRNNV 25546

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
             TLKW +P  +GGS IT YI+E K +    W K         E  +  + E     FR+ A
Sbjct: 25547 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 25606

Query: 1943  ENTVG-VSLPTES 1954
              N  G  S P++S
Sbjct: 25607 RNAAGNFSEPSDS 25619



 Score =  229 bits (561), Expect = 5e-58
 Identities = 207/857 (24%), Positives = 348/857 (40%), Gaps = 45/857 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284
             VTW+K    IE      +   +   +L +R  T D +  YT    +A  + K  +KV+V 
Sbjct: 28917 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28976

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
             + P K+V   R   I  G  +TL  D        P   +I+  +   +          ++
Sbjct: 28977 DTPGKVVGPIRFTNIT-GEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEA 29035

Query: 1343  ASLTIKKVENTDAGIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
              S T  K+ N +   +++   N  G      +D  +       P  PG P    I  +SI
Sbjct: 29036 QSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 29095

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454
              + W  PE+ G S I  Y++E +E  +T W+ V   + I++T+  +  L   + Y F   
Sbjct: 29096 TLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 29155

Query: 1455  AVNEVDISDASETTEYYKVIKETKIQSP-TVEKPLKNITTEPNEDIELTCIFGGVP---- 1509
             A N   +  AS  +   K  +      P TV K      T  + +       GG+     
Sbjct: 29156 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 29215

Query: 1510  --QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG- 1566
               +       D  K+  A+A  + R               ++  A N  G+ ++  V G 
Sbjct: 29216 IIEMCKADLGDWHKVN-AEACVKTRYTVTDLQAGEEYK--FRVSAINGAGKGDSCEVTGT 29272

Query: 1567  IQQKPVITISNEDI----KQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             I+    +T    DI    KQ H V  G    +    +G P P  +W K  + L      +
Sbjct: 29273 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS--LRAD 29330

Query: 1621  ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
             I T +  S + ++   R+ + KYT+   N +G+ S+  T+KV D P  P GP+  ++++R
Sbjct: 29331 IHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTR 29389

Query: 1681  ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
              S T+ W  PL DGG  +  Y +EK E     W +V       + + +  L E   Y FR
Sbjct: 29390 GSATLMWDAPLLDGGARIHHYVVEKREASRRSW-QVISEKCTRQIFKVNDLAEGVPYYFR 29448

Query: 1741  VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
             V A N  G  E  E    ++ T    P               S  + W   + +GGS I 
Sbjct: 29449 VSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDT---SKSSAVLAWLKPDHDGGSRIT 29505

Query: 1801  DYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
              Y +E++Q+G   W            +++L   T Y+FR+ A+N+ G S P  +   + I
Sbjct: 29506 GYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 29565

Query: 1860  GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTV 1918
              +    P+     + ++  +      +T      G P      + + ++ K   ++ +T 
Sbjct: 29566 KEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 29625

Query: 1919  GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
                     +++    D   + ++ ENT GV   T S +V +      P P T P+E+  V
Sbjct: 29626 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVK--TFSVTVVVIGR---PGPVTGPIEVSSV 29680

Query: 1979  GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
              +   + SWG P+  GG  +  Y +  R+   T W  V    V   +  +  L++   Y 
Sbjct: 29681 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYS 29739

Query: 2039  IRIYARNEIGLSEPLES 2055
              R+ + N  G+S+PLES
Sbjct: 29740 FRVSSENRFGVSKPLES 29756



 Score =  229 bits (559), Expect = 8e-58
 Identities = 268/1206 (22%), Positives = 488/1206 (40%), Gaps = 88/1206 (7%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            +P F ++ +P        V    +V G P  +ITWF+   I++  + ++ +   D++ +L
Sbjct: 5319 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFI-QDHLVSL 5377

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             I +    DAG + C   N  G +  +  + +  P S    ++              A +
Sbjct: 5378 QILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS-FIKKIESTSSLRGGTAAFQATL 5436

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF-KGEEIVPDENISVAIESD 687
               +P T +    +  + E  +I +        E ++A L+  G E+  D       ++D
Sbjct: 5437 KGSLPITVTWLKDSDEITEDDNIRMTF------ENNVASLYLSGIEVKHDGKYVCQAKND 5490

Query: 688  MHMY-CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIEPLKSMI 745
              +  CS L   +VK  +  T T  AV+ +     P  L++K +G KE       + +  
Sbjct: 5491 AGIQRCSAL--LSVK--EPATITEEAVSIDVTQGDPATLQVKFSGTKE-------ITAKW 5539

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
             + G+ + L ++   +   T++  K                    I+  +K KD G YT 
Sbjct: 5540 FKDGQELTLGSKYKISVTDTVSILK--------------------IISTEK-KDSGEYTF 5578

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            + +N  G +   A I V     +   PP F  + +++   +   I L   V  +   SI 
Sbjct: 5579 EVQNDVGRSSCKARINV----LDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 5634

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W+++++ IS SE    +F      L I+ ++   DSG Y C A+N AG +     +T+  
Sbjct: 5635 WFKDDQEISASEKYKFSFHDNTAFLEISQLEG-TDSGTYTCSATNKAGHNQCSGHLTVK- 5692

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983
            E   FV+  Q S +      V L+     T  ++ KW+ + KE+     R + ++     
Sbjct: 5693 EPPYFVEKPQ-SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS 5751

Query: 984  XXXXXXXXXDVGVIKC-IVKDQETST---MLVVKETIPEFIRKLQDFEV-KEKDVAILEV 1038
                     D G   C +  D  T+T    L VKE  P+FI+K     V +       E 
Sbjct: 5752 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP-PQFIKKPSPVLVLRNGQSTTFEC 5810

Query: 1039 EI-NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
            +I  +    V W  DG EI   +K+   F     +    I    V + G Y C  R+++ 
Sbjct: 5811 QITGTPKIRVSWYLDGNEITAIQKHGISF--IDGLATFQISGARVENSGTYVCEARNDAG 5868

Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152
            TA  ++   V+ PP  I  L+  +V K +    E E+T      V W K+  EI+ S   
Sbjct: 5869 TASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKY 5928

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             LT       L I  CD  D GEY C    E G+  C+  + ++EP  +F  ++     V
Sbjct: 5929 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP-SFIKKIENTTTV 5987

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
              ++  + +       + +TW K   ++++ +   +       TL IR         YTC
Sbjct: 5988 LKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTC 6047

Query: 1269 VLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
               +     +     +V+ P +IV+  +   +     +TL       P+   +W+ + K 
Sbjct: 6048 QAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQ 6107

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-K 1386
            I   ++   S ++  AS  I+ V   D+G Y  ++EN+ G +  +  + +LD+  PP   
Sbjct: 6108 IVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 6167

Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTT-EWISVKNITKTQTSIQNLK 1444
              + ++D    +    E + +G+  I   +  + +EI T+ ++  V +       + NL+
Sbjct: 6168 KKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLE 6227

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
               +  +    V+ V   DA         I   K     + KP +     P+  +E   I
Sbjct: 6228 LEDTANYTC-KVSNVAGDDACSG------ILTVKEPPSFLVKPGRQ-QAIPDSTVEFKAI 6279

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P  K+ W++D  +L +    +     +                Y C   ND G   
Sbjct: 6280 LKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDS 6339

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             + ++ + + P   +   +  +  K GD   +   I G P   V+W++N ++L    +Y 
Sbjct: 6340 CTTMLLVTEPPKF-VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYR 6398

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            +T  +  +VI++  L    S  +  EA N AG++S    + V + P     P I+  +  
Sbjct: 6399 MTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKN 6458

Query: 1681 ESVTIE 1686
              V++E
Sbjct: 6459 AEVSLE 6464



 Score =  227 bits (555), Expect = 3e-57
 Identities = 209/895 (23%), Positives = 364/895 (40%), Gaps = 51/895 (5%)

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVKKRT 1252
             P+I+ +    + I VPA     L + I        +W+   S + ++E+ T+ +  K   
Sbjct: 30663 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 30722

Query: 1253  LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
             L IR+ T  D  EYT  L +   TT   ++V+    K        +I      ++ + ++
Sbjct: 30723 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILD-KPGPPTGPIKIDEIDATSITISWE 30781

Query: 1313  AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT---IKKVENTDAGIYKLRLE--NNCG 1367
               P+ +    ++  ++++    +P     S S+T    K    T+   Y  R+   N  G
Sbjct: 30782 P-PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 30840

Query: 1368  HADVEMNVTI-----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
                   +  I     +  P PP    I ++    + + W  PE+ G S +  Y+VE +E+
Sbjct: 30841 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEV 30900

Query: 1423  DTTEWISVKNITKTQTSIQN--LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
                 W+ V  +  T T  ++  L     Y  R  A+N       S  ++   ++    I 
Sbjct: 30901 RADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSK--PIVAMDPIA 30958

Query: 1481  SP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKTAKATYENRX 1533
              P   + P    TT  +  +  + +       KVT Y       D  +      T     
Sbjct: 30959 PPGKPQNPRVTDTTRTSVSLAWS-VPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 31017

Query: 1534  XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQKH------KV 1586
                           ++ +A N  G  E + V G ++   ++   + ++ +++      + 
Sbjct: 31018 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQ 31077

Query: 1587  GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
             G    +T  I+G P P   W K G  +   K   I T E  + + IKE  R  S  Y + 
Sbjct: 31078 GGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATSETHTELVIKEADRGDSGTYDLV 31135

Query: 1647  ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
               N  G  +V + ++V   P+ PEGP+   +I   SV + W+PP DDGG ++  Y +E+ 
Sbjct: 31136 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 31195

Query: 1707  EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALD 1765
             E     W  +    R   +  ++ L EN EY FRV A+N  G S+ L+S EP+  KT L+
Sbjct: 31196 EVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLN 31254

Query: 1766  VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXXX 1822
              P           +   SV ++W   + +GGS +  Y +E K+    KW           
Sbjct: 31255 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTT 31314

Query: 1823  XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
                +  L  +  YQFRI A+N++G S    + + +        PSQP    +   +  SV
Sbjct: 31315 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 31374

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
             TL+W +PE +GG  I  Y +E++     +W K         +  I  + E  E  FR+ A
Sbjct: 31375 TLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFA 31434

Query: 1943  ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
             EN  G+S P  + ++ ++   T    P    E++ V + +           G A  L   
Sbjct: 31435 ENETGLSRPRRT-AMSIKTKLTSGEAPGIRKEMKDVTTKL-----------GEAAQLSCQ 31482

Query: 2003  IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             I  R +    W   GK  + + K+ +      HT  +    + + G+   + ++E
Sbjct: 31483 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 31537



 Score =  227 bits (554), Expect = 3e-57
 Identities = 206/781 (26%), Positives = 325/781 (41%), Gaps = 48/781 (6%)

Query: 1207  LVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             LV A     + VEIP        VTW K   +++ T++    +      L I +C   D 
Sbjct: 22001 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDS 22060

Query: 1264  CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
               Y    L A++      +V+      +       IK     +  V +   P  ND  + 
Sbjct: 22061 GPYP---LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 22117

Query: 1324  NSKIIKKCKHTKPSIDSKSASLTIK---KVENTDAGI---YKLRLENNCGHADVEMNVTI 1377
              S  + + + T  +   + A+  I+   K      G+   ++++ +N  G      +  I
Sbjct: 22118 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACI 22177

Query: 1378  LDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
             +       P PPG P +  +   S+ I W EP + G S I+ Y VE +E +   W +V  
Sbjct: 22178 VANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSK 22237

Query: 1433  ITKTQTSIQN--LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
                     ++  L    +Y FR  A N    S  S+ +E   ++    I  P    PL N
Sbjct: 22238 ALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE--PMLALDPIDPPGKPVPL-N 22294

Query: 1491  ITTEP-NEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
             IT              GG    K+T Y    RD    +  KA + N              
Sbjct: 22295 ITRHTVTLKWAKPEYTGGF---KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTED 22351

Query: 1546  XXY--KCIAFNDHGEV----ETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAV 1595
               Y  + IA N  G +    E S  +  +          D+K K     K G+ + + A 
Sbjct: 22352 AAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEAD 22411

Query: 1596  IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             + G PPP + W K+G +LE   +  I   + ++ +  K+  R  S  YT+ A+N  G + 
Sbjct: 22412 VSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 22471

Query: 1656  VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
                 +KV D+P  PEGP+ + E++ E   + W PPLDDGG ++  Y ++K E     W  
Sbjct: 22472 HIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTN 22531

Query: 1716  VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
             VA  +  V    + KL +  EY+FRV+A N  G  E LESEP++       P        
Sbjct: 22532 VAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYG-PPDPPKNPE 22589

Query: 1776  XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSIN 1832
                I  +S+ + W   + +GGS II+Y VE + + G++W           R  +  L+  
Sbjct: 22590 VTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEG 22649

Query: 1833  TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
               Y+FRI A N  G S P  +        T+  P  P N  V +++  S+++ W +P  +
Sbjct: 22650 HEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYD 22709

Query: 1893  GGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
             GGS IT Y++E    +   W +IVT   G     + I  + E  E   RI A N+ G+  
Sbjct: 22710 GGSEITGYMVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 22768

Query: 1951  P 1951
             P
Sbjct: 22769 P 22769



 Score =  225 bits (550), Expect = 1e-56
 Identities = 249/1194 (20%), Positives = 467/1194 (39%), Gaps = 94/1194 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+++L P  +     V  ECQV+   +  +TW +    + P +D+++ + +D +ATL 
Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATLE 4629

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I     +D+GT+ C A N AG +S +  + V  P S                       +
Sbjct: 4630 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS----------------------FV 4667

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            + + P++   P       G    L C+L   P   + W    +E+     + +   +   
Sbjct: 4668 KKVDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSE- 4719

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               ++L IT+VK    G+Y+  AVN  G  S    + I    KEPP  I+ L+   + +G
Sbjct: 4720 ---AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI----KEPPSFIKTLEPADIVRG 4772

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKA 807
             + +L  +V G     I+W K+ K +++          S+  L+       D G Y    
Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G     A       T    EPP F+ +  ++      T+ L A V  +   S+TW 
Sbjct: 4833 ANEVGKCGCMA-------THLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 4885

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            +  E+I     I  +F      L+I +V      G Y C+A N AG  +    + +  E 
Sbjct: 4886 KGQEVIREDGKIKMSFSNGVAVLIIPDVQISF-GGKYTCLAENEAGSQTSVGELIVK-EP 4943

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
               ++  +   +   G    LE   + T  +  KWY + + +       I  +       
Sbjct: 4944 AKIIERAE-LIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLK 5002

Query: 986  XXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
                   D G     + ++      ET+  ++ ++  P F + L++ +        L+ +
Sbjct: 5003 FYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCK 5062

Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ES 1095
            I  S    V W +DG+ I    ++Y          L I    ++D G ++C   +     
Sbjct: 5063 IAGSLPMRVSWFKDGKEI-AASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSK 5121

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
             ++   +V+ PP  +T+  ++ V  G+    +        L +RWFK   E+       +
Sbjct: 5122 DSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYI 5181

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            T +  +  L++Y     D+G Y+C+V    G  +C+A L V+EP+  F  +L    L+  
Sbjct: 5182 TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA-TFVEKLEPSQLLKK 5240

Query: 1211 NTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268
                 L  ++     + +TW+     I+++ K  +        L +     +D  EY C 
Sbjct: 5241 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 5300

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
               +A S     + +V+  P      +   + +  DV LL +    P     W  ++ I+
Sbjct: 5301 AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 5360

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
            +  +  K  I     SL I K    DAG Y+ R+ N  G +     VT+ + PS      
Sbjct: 5361 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS-----F 5415

Query: 1389 ILEIDS-SSINICWDEPENTGNSTIIYYVVEYQEID-TTEWISVKNITKTQTS---IQNL 1443
            I +I+S SS+       + T   ++   V   ++ D  TE  +++   +   +   +  +
Sbjct: 5416 IKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGI 5475

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
            +     ++   A N+  I   S        +KE      T+ +   +I     +   L  
Sbjct: 5476 EVKHDGKYVCQAKNDAGIQRCSALLS----VKE----PATITEEAVSIDVTQGDPATLQV 5527

Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             F G  +    W++DG++L    K   +  +                 Y     ND G  
Sbjct: 5528 KFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRS 5587

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKE 1618
                 + +    +     + +K+   +   ++ +  ++ G  P  + W+K+  ++   ++
Sbjct: 5588 SCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEK 5647

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            Y  +  + T+ + I +L+ + S  YT  A+N AG +     L V + P   E P
Sbjct: 5648 YKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKP 5701



 Score =  224 bits (548), Expect = 2e-56
 Identities = 224/984 (22%), Positives = 400/984 (40%), Gaps = 67/984 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P T  +KP++  V  G    LEC +   PE    W   G+E+  D    ++  + +    
Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV---- 8567

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            S LKI NV     G Y+    N  G+ S    L++ +    PP     LK      G SV
Sbjct: 8568 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV-SDRTVPPSFTRKLKETNGLSGSSV 8626

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            ++  +V G+P  +++W      + +     T    +T ++T+   ++  D G YT  A N
Sbjct: 8627 VMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEE-SDSGDYTCIATN 8685

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G  E SA +TV EP       P F+ +   + V     +   + V   P  S++W++ 
Sbjct: 8686 MAGSDECSAPLTVREP-------PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKG 8738

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            +  + P +    + +    EL + +VD+   SG+Y C+ SN AGK+S    + I      
Sbjct: 8739 SSELVPGDRCNVSLEDSVAELELFDVDTS-QSGEYTCIVSNEAGKASCTTHLYIKAP-AK 8796

Query: 930  FVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            FVK L   Y  E+GK +ILE   + T  +S  W  N   ++      I    +       
Sbjct: 8797 FVKRLN-DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIP 8855

Query: 988  XXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NS 1042
                 D G   C +++       S  +++ E  P F+++L+  +V   D A L+ ++  +
Sbjct: 8856 SSTVEDAGQYNCYIENASGKDSCSAQILILEP-PYFVKQLEPVKVSVGDSASLQCQLAGT 8914

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTA 1098
                V W +    ++P    Y    R ++  L      ++D GEY C   +     S + 
Sbjct: 8915 PEIGVSWYKGDTKLRPTTT-YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAST 8973

Query: 1099 EVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
             +TV E  LPP    +L++ +   G    F+  ++  + + V W+KDG  ++ S ++Q +
Sbjct: 8974 FLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTS 9033

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVP 1209
                   L I+  D   AG+YSC   N      S    ILT  +    F +RL     V 
Sbjct: 9034 FLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV 9093

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              +  +       + + V+W K    I    K+ +        L + K  + D  +YTC 
Sbjct: 9094 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 9153

Query: 1270 LLDA----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP-NDEWIVN 1324
             ++       T +L ++    PP       E   +   +   L    A  QP    W  N
Sbjct: 9154 AVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN 9213

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
            +  I+   + + +  + +  L ++K    DAG+Y  ++ N+ G A    ++ I +   PP
Sbjct: 9214 NIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 9273

Query: 1385 G-KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
                ++  +  S            G+  I I ++   +EI  ++  S      + T++  
Sbjct: 9274 VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS--FASGTAVLE 9331

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN----ITTEPN-- 1496
            L+  +      Y     +++  S+TT+    IK+    +P  +K   +      +EP   
Sbjct: 9332 LRDVAKADSGDYVCKASNVA-GSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSI 9390

Query: 1497 ---EDIELTCI--FGGVPQPKVTWYRDG-KKLKTAKATYENRXXXXXXX----XXXXXXX 1546
               E    T I   GG P P V W +   ++L      + ++                  
Sbjct: 9391 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 9450

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQK 1570
             Y+C+AFN+HGE+E++  + + ++
Sbjct: 9451 LYRCVAFNEHGEIESNVNLQVDER 9474



 Score =  224 bits (547), Expect = 2e-56
 Identities = 238/963 (24%), Positives = 395/963 (41%), Gaps = 77/963 (7%)

Query: 1141  KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200
             +D  E+QF+  ++  ++G + + ++   +     + S  VG   C      + P +  ++
Sbjct: 16996 RDVEELQFT--VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC------QRPDMPPSI 17047

Query: 1201  RLPEFILVPANTDAYLTVEIPDETLD-VTWYK--------KKSVIEDTEKFTLISDVKKR 1251
              L EF+ V   T+  +  +I       +TW+K        K+ V+ DT    L+ D    
Sbjct: 17048 DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD-DTC 17106

Query: 1252  TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             TL+I +    D   YT   ++   T   ++++ V+  P   V    ++       +TL  
Sbjct: 17107 TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVG-PIKFESVSADQMTL-- 17163

Query: 1310  DYQAFPQPND--EWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDAGIYKLRLE 1363
                 FP  +D    I N  I K+  + K     S + K  + TI K+      ++++  +
Sbjct: 17164 --SWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 17221

Query: 1364  NNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             N  G      ++ E    +   P  P KP +  +  +S+ + W+EPE  G S +  Y +E
Sbjct: 17222 NKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE 17281

Query: 1419  YQEIDTTEWISV-KNITKTQT-----SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
              ++  +  W  V ++  K  T      +  L   S Y+FR YA+N   +  AS  ++   
Sbjct: 17282 MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSD--P 17339

Query: 1473  VIKETKIQSPTVEKPLKNITTEPNEDIELTCIF---GGVPQPKVTWYRDGKKLKTAKATY 1529
                   I  P    P     T+ + D+E +      G      +  Y++  K +  K   
Sbjct: 17340 ATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKD 17399

Query: 1530  ENRXXXXXXXXXXXXXXXYK----CIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKH 1584
             +                 YK     +     GE  E + V+ ++ + V      D   + 
Sbjct: 17400 KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 17459

Query: 1585  KV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
             ++    G    + A + G PPP V W  N   L   +E  I T   +S + IK  +RSH 
Sbjct: 17460 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP--QEATIETTAISSSMVIKNCQRSHQ 17517

Query: 1641  SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
               Y++ A N AG     + + V D P     P +   ++ ES  + W  P DDGG  +T 
Sbjct: 17518 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 17577

Query: 1701  YAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758
             Y IEK E D   W  V   V R   T  +Q L +   Y FR+ A+N +G    +E SE +
Sbjct: 17578 YVIEKRESDRRAWTPVTYTVTRQNAT--VQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 17635

Query: 1759  VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818
             VI+  + VP             N +V +TW P + +GGS II+Y +E +  G +      
Sbjct: 17636 VIREPITVPERPEDLEVKEVTKN-TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVT 17694

Query: 1819  XXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                  +R   ++ L    TY++R+ A N +G   P      IT    L PP+   +F   
Sbjct: 17695 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 17754

Query: 1876  ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK-- 1933
              +         T   S    P  ++  +   V     T I T   ++    +E IK K  
Sbjct: 17755 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL---ALEKIKAKRS 17811

Query: 1934  DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
             D   + +  EN+ G S     Q   +++    P PP  P+    V  + ++ SW  P  D
Sbjct: 17812 DSGKYCVVVENSTG-SRKGFCQVNVVDR----PGPPVGPVSFDEVTKDYMVISWKPPLDD 17866

Query: 1994  GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
             GG+ +  Y I  ++V K +WM V      T    +  L E   Y+ RI+A N  G+S+PL
Sbjct: 17867 GGSKITNYIIEKKEVGKDVWMPVTSASAKT-TCKVSKLLEGKDYIFRIHAENLYGISDPL 17925

Query: 2054  ESD 2056
              SD
Sbjct: 17926 VSD 17928



 Score =  223 bits (545), Expect = 4e-56
 Identities = 192/796 (24%), Positives = 337/796 (42%), Gaps = 44/796 (5%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVK 1249
             +E P I+        + V A ++  + + I  + L      +  V ++ T +F      +
Sbjct: 27398 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 27457

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
               T+ +++    D   Y     ++  TTK  + +V    +         I   ++ ++ +
Sbjct: 27458 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD-RPGPPTGPVVISDITEESVTL 27516

Query: 1310  DYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI---YKLRLENN 1365
              ++         + N  ++K+   T    + S + + T+ KV     G    ++++ EN 
Sbjct: 27517 KWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENR 27576

Query: 1366  CGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
              G +D   +  +  K     P PP  P +  +   SI + W EP + G S ++ Y +E +
Sbjct: 27577 FGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK 27636

Query: 1421  EIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             + ++  W       I  T   +  +     Y FR YA N   +   S  +E   V+    
Sbjct: 27637 DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSE--PVLAIDA 27694

Query: 1479  IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXX 1534
              + P   +         +   +     GG    K+T Y    RD    +  KA++ N   
Sbjct: 27695 CEPPRNVRITDISKNSVSLSWQQPAFDGG---SKITGYIVERRDLPDGRWTKASFTNVTE 27751

Query: 1535  XXXXXXXXXXXXXYKCIAF--NDHGEVET-SCVVG------IQQKPVITISNEDIKQ-KH 1584
                          Y+   F  N  G +   S VVG          PVI +  E  +  K+
Sbjct: 27752 TQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKY 27811

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             + G    + A I G P P + WYK+  +L+ +    +      + I IK+  R +S  Y 
Sbjct: 27812 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 27871

Query: 1645  IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             ++  N  G++S  + +++ DKP  P GP+  + ++ E +T+ W+PP DDGG ++T Y +E
Sbjct: 27872 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 27931

Query: 1705  KHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
             K E     W  V++ ++  + T    K+ +  EY+FRV A N  G  E LES+ +V K A
Sbjct: 27932 KRETSRVVWSMVSEHLEECIIT--TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 27989

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXX 1821
                P           I   S+ + W     +GGS I  Y +E K++ K   W        
Sbjct: 27990 FVTPG-PPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLE-KRDKKSLGWFKVLKETI 28047

Query: 1822  XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI-TIGKTLTPPSQPRNFVVSEST 1878
                R  +  L+ N+ YQ+R+ A N  G   P++   +       + PP  P    +++ST
Sbjct: 28048 RDTRQKVTGLTENSDYQYRVCAVNAAGQG-PFSEPSEFYKAADPIDPPGPPAKIRIADST 28106

Query: 1879  SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEII 1937
               S+TL W++P  +GGS +T Y++E +  + + WT + T G     E+ + N+K      
Sbjct: 28107 KSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYY 28166

Query: 1938  FRISAENTVGVSLPTE 1953
             FR+SA N  G   P E
Sbjct: 28167 FRVSAVNCAGQGEPIE 28182



 Score =  223 bits (544), Expect = 6e-56
 Identities = 198/807 (24%), Positives = 354/807 (43%), Gaps = 56/807 (6%)

Query: 1191  VEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
             ++EP I  T  L      L+     +  T+++P        VTW  ++  +++T++ ++ 
Sbjct: 29565 IKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSIT 29624

Query: 1246  SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSD 1304
             +   + TL ++     D   Y   L +        V VV    P  V    E  +   S 
Sbjct: 29625 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSA 29682

Query: 1305  VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP--SIDSKSASLTIKKVENTDAGIYKLRL 1362
              + ++ +          I N  + K+   T     ++S      IK    T    Y  R+
Sbjct: 29683 ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRV 29742

Query: 1363  --ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
               EN  G +    +  I+ +     PS P +P +  + +++++I W+EP + G S II Y
Sbjct: 29743 SSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGY 29802

Query: 1416  VVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
              VE +E +T  W+    +   + +  +  L     Y+FR YA+N   +S ASE +    +
Sbjct: 29803 WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR--PI 29860

Query: 1474  IKETKIQSP-------TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
             + +  + +P            +  I + P  D     +   + +  V+   DG+ LK   
Sbjct: 29861 MAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLK-CN 29919

Query: 1527  ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV----ETSCVVGIQQKPVITISNEDIKQ 1582
              T  +                ++ +A N  G +    E++  V  + +     +  D + 
Sbjct: 29920 YTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARL 29979

Query: 1583  KH-----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
                    + G + ++ A + G P P++IW K   +L+  ++ ++    K +   IK   R
Sbjct: 29980 HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDR 30039

Query: 1638  SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
             S S KYT+   N +GT +V V +KV D P  P G + +  +++E  T+ W  P +DGG E
Sbjct: 30040 SDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTLAWSLPQEDGGAE 30098

Query: 1698  LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757
             +T Y +E+ E     W+ + + +    +Y + +L +N EY+FRV A N  G    +ESEP
Sbjct: 30099 ITHYIVERRETSRLNWV-IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 30157

Query: 1758  IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KW-- 1813
             IV + +  +PS             E + I W   E +GG+ I +Y V+ K+E K  +W  
Sbjct: 30158 IVARNSFTIPSPPGIPEEVGT-GKEHIIIQWTKPESDGGNEISNYLVD-KREKKSLRWTR 30215

Query: 1814  -KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK---TLTPPSQP 1869
                         ++  L     YQFR+ A N  G S P  + + I+  +   T  PPS P
Sbjct: 30216 VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAP 30275

Query: 1870  RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCI 1927
             R   V ++T  S++L WT+P  +GG+ I  Y++E +      W ++ T   ++   E  +
Sbjct: 30276 R---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHT-NATIRNTEFTV 30331

Query: 1928  ENIKEKDEIIFRISAENTVGVSLPTES 1954
              ++K   +  FR++A N  G+S  +ES
Sbjct: 30332 PDLKMGQKYSFRVAAVNVKGMSEYSES 30358



 Score =  221 bits (540), Expect = 2e-55
 Identities = 185/703 (26%), Positives = 304/703 (43%), Gaps = 40/703 (5%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV----KNITK 1435
             KPSPP  P  ++   +S+++ W  P + G S I+ Y+VEYQ++   EW       ++  +
Sbjct: 18039 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 18098

Query: 1436  TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
             T+  +  L+   +Y+FR  AVN    SD +   E   V+ + +++ P +     N+  E 
Sbjct: 18099 TKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPE--PVLVKDRLEPPELILDA-NMAREQ 18155

Query: 1496  N----EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXY 1548
             +    + + L+ I  GVP PKVTW ++ +   T KA  +                    Y
Sbjct: 18156 HIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIY 18214

Query: 1549  KCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWY 1607
                  N  G    S  V +  KP      E  + +K      W       G      +  
Sbjct: 18215 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 18274

Query: 1608  KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYD 1664
             +           + T+K+K+     K L   +   + + A N  G      T   +K  D
Sbjct: 18275 RRDVASAQWSPLSATSKKKSHFA--KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 18332

Query: 1665  KPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
              P  P GP   +   ++ +  V++ W  P  DGG  +T Y +E  E     WIK   V  
Sbjct: 18333 -PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVT- 18390

Query: 1722  DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
             ++E   +  L +   Y FRV A+N VG      + PI  +  L  PS          +  
Sbjct: 18391 NLECV-VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVV 18449

Query: 1782  ESVYITWFPSEKNGGS-PIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
             ++     FP+   G   P   +     EIK + + +            I+      T ++
Sbjct: 18450 KAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSVLTIKNCLRRDTGEY 18508

Query: 1838  RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
             +I   N  G+    T    +T+     PP+ P N +  + T   +T+ W  P+ +GGSP+
Sbjct: 18509 QITVSNAAGSK---TVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPV 18563

Query: 1898  TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
              NYI+E +  +  +W  +V+ G S  +  I ++++  E +FR+ AEN +GV  P +S   
Sbjct: 18564 INYIVEKQDTRKDTWG-VVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 18622

Query: 1958  RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
               +   + PSPP  P+ +  +  N    SW  P+ DGG+P+ GY +  R+VT   W+ V 
Sbjct: 18623 VAKHKFSPPSPPGKPV-VTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVN 18680

Query: 2018  KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             K  +  LKF +  L E +TY  R++A N  GLS+P  S +P K
Sbjct: 18681 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIK 18723



 Score =  220 bits (538), Expect = 3e-55
 Identities = 238/1072 (22%), Positives = 437/1072 (40%), Gaps = 75/1072 (6%)

Query: 633  PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHM 690
            P TF +K + +Q + +G    L C++   P   I W     EI       ++ +ES    
Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVES---- 5280

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
              +VL++T+V     G Y   A N  G      ++ +    KE P   +  K + V +  
Sbjct: 5281 -TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV----KESPYFTKEFKPIEVLKEY 5335

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV-KDEGVYTLKAE 808
             V+L A+V G P   ITW K+N  +++    K+    H +++   K V  D G Y  +  
Sbjct: 5336 DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVT 5395

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G +  SA +T+        EPP FI + +  +    GT    A +  +   ++TW +
Sbjct: 5396 NEVGSSICSARVTLR-------EPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLK 5448

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            +++ I+  + I   F+     L ++ ++ + D G Y C A N AG     A +++  E  
Sbjct: 5449 DSDEITEDDNIRMTFENNVASLYLSGIEVKHD-GKYVCQAKNDAGIQRCSALLSVK-EPA 5506

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDHR----------EI 975
            T  +    S +  +G    L+ + S T  ++ KW+ + +E++ G  ++          +I
Sbjct: 5507 TITEE-AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKI 5565

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE-VKEKDVA 1034
            I   +            DVG   C  K +     L++    P F +KL+  + +K   + 
Sbjct: 5566 ISTEKKDSGEYTFEVQNDVGRSSC--KARINVLDLIIP---PSFTKKLKKMDSIKGSFID 5620

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            +  +   S    + W +D + I   + KY F    +   L I      D G Y+C   ++
Sbjct: 5621 LECIVAGSHPISIQWFKDDQEISASE-KYKFSFHDNTAFLEISQLEGTDSGTYTCSATNK 5679

Query: 1095 S----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQF 1148
            +    C+  +TV E PP  + + Q+Q VN   +   +  L  G A   ++WFKD  E+  
Sbjct: 5680 AGHNQCSGHLTVKE-PPYFVEKPQSQDVNPNTRVQLK-ALVGGTAPMTIKWFKDNKELHS 5737

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204
                 +  D     L+++     D+G Y C    +VG +   A L V+EP        P 
Sbjct: 5738 GAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPV 5797

Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
             +L    +  +         + V+WY   + I   +K  +       T  I     ++  
Sbjct: 5798 LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 5857

Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             Y C   +   T    +E+ V+ PP  +   +   + + SDV L  +    P     W+ 
Sbjct: 5858 TYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLK 5917

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            N++ I+  K    +      +L I K + +D G Y+  + N  G       V + + PS 
Sbjct: 5918 NNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSF 5977

Query: 1384 PGK-PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SI 1440
              K  N   +  SS      +    G+  I I ++ + Q +D  + + +  +    T  I
Sbjct: 5978 IKKIENTTTVLKSSATF---QSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQI 6034

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            +++    S R+   A NE  +    E    + +++E    +  VEK  K++     + + 
Sbjct: 6035 RSVDNGHSGRYTCQAKNESGV----ERCYAFLLVQE---PAQIVEK-AKSVDVTEKDPMT 6086

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR-XXXXXXXXXXXXXXXYKCIAFNDH 1556
            L C+  G P+ KV W +DGK++  ++    ++EN                 Y     ND 
Sbjct: 6087 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            G       + +  + +     + + +  KV G    +   + G  P    W+K+G ++  
Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
              +Y +   E++  + +  L+   ++ YT + SN AG  +    L V + PS
Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPS 6258



 Score =  220 bits (537), Expect = 4e-55
 Identities = 207/803 (25%), Positives = 340/803 (42%), Gaps = 53/803 (6%)

Query: 1202  LPEFI-LVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
             LP+   L   N++  L + I  +    V+W K +  +    + ++ S     TLI+  C 
Sbjct: 20914 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQ 20973

Query: 1260  EDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
             + D  +YT  L +   T +  + + V   P I     ++       +TL     A P+ +
Sbjct: 20974 KSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK---WAPPKDD 21030

Query: 1319  DEWIVNSKIIKK--CKHTKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHADVEM 1373
                 + + I++K    + K    + +   T  +V     G+   +++  EN  G  +   
Sbjct: 21031 GGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLK 21090

Query: 1374  NVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
             +  I+     D P  P  PNI+++   S+++ W +P+ TG S I  Y +E++E ++  W 
Sbjct: 21091 SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLW- 21149

Query: 1429  SVKNITKTQTSIQNLKTNS-----SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
               K   KT   +++ K         Y FR  A+N   +   S  +E   V+    I  P 
Sbjct: 21150 --KRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSE--PVVALDPIDPPG 21205

Query: 1484  VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXX 1539
               + + NIT      I     + G    K+T Y    RD       KA + N        
Sbjct: 21206 KPEVI-NITRNSVTLIWTEPKYDG--GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 21262

Query: 1540  XXXXXXXXY--KCIAFNDHGEV-------ETSCVVGIQQKPVITISNEDIKQ--KHKVGD 1588
                     Y  +  A N  G +       ET       + P I + +  IK     K GD
Sbjct: 21263 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVL-DPTIKDGLTIKAGD 21321

Query: 1589  EWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
               ++ A+ I G P P+  W K G  +       IT+   +S++ IK   R  + +YTI A
Sbjct: 21322 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITA 21381

Query: 1648  SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
             +N  GT    V + V D P  P GPV +  +S E  T+ W PPL+DGG  +  Y +EK E
Sbjct: 21382 TNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 21440

Query: 1708  PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
                  W  V++ D     +   KL +  EY+FRV A N  G  E ++SEP+ +      P
Sbjct: 21441 TSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPP 21499

Query: 1768  SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR- 1825
                          N +  ++W     +GGS I  Y VE ++ +  +W           R 
Sbjct: 21500 GPPEKPEVSNVTKNTAT-VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 21558

Query: 1826  -IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
              +  L   +TY+FR+ A N  G   P  + D + +     PP  P N  V+++T +S +L
Sbjct: 21559 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 21618

Query: 1885  KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAE 1943
              W +P  +GG  IT Y++E + V  ++W K  T     + +  + +++ K++  FRISA 
Sbjct: 21619 AWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAI 21678

Query: 1944  NTVGVSLPTESQSVRLEKHATVP 1966
             N  GV  P     V + +    P
Sbjct: 21679 NDAGVGEPAVIPDVEIVEREMAP 21701



 Score =  219 bits (534), Expect = 9e-55
 Identities = 226/1068 (21%), Positives = 428/1068 (40%), Gaps = 58/1068 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F KKP      +G+D+ LEC L   P   ++W     E+   +   +  E+    + 
Sbjct: 8325 PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSEN----FL 8380

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + + I NV     G Y   A N  G  +    + +K     PP+ ++ L  +    G+ V
Sbjct: 8381 TSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA----PPRFVKKLSDISTVVGKEV 8436

Query: 753  ILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809
             L   + G    ++ W K+  + V+         + +I  L+  +V+  + G YT + +N
Sbjct: 8437 QLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 8496

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G+ E  A ++V        EP   + + + I V    T  L   V   P  S  W+++
Sbjct: 8497 DAGMQECFATLSV-------LEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKD 8549

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV- 928
             + ++       +F  +   L I NV +  DSG Y     N  GK S  A + +    V 
Sbjct: 8550 GKELTSDNKYKISFFNKVSGLKIINV-APSDSGVYSFEVQNPVGKDSCTASLQVSDRTVP 8608

Query: 929  -TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             +F + L+++     G +V++EC+   S  +S  W+H   EIS     +           
Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 8667

Query: 986  XXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEI 1040
                   D G   CI  +     E S  L V+E  P F++K    +V    +V    +  
Sbjct: 8668 VNMLEESDSGDYTCIATNMAGSDECSAPLTVREP-PSFVQKPDPMDVLTGTNVTFTSIVK 8726

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
             +    V W +    + P  ++ +      + +L + +      GEY+CI+ +E+  A  
Sbjct: 8727 GTPPFSVSWFKGSSELVPG-DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 8785

Query: 1101 TV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
            T    ++ P + + RL +  + KG     E   T    + V W K+G  +  S    +T 
Sbjct: 8786 TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITT 8845

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
              K   L+I    ++DAG+Y+C +    G   C+A + + EP   F  +L E + V    
Sbjct: 8846 TEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPY-FVKQL-EPVKVSVGD 8903

Query: 1213 DAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-- 1269
             A L  ++     + V+WYK  + +  T  + +       TL+  +   +D  EY C   
Sbjct: 8904 SASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE 8963

Query: 1270 --LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
              + +  ++T L V+  + PP      R+ +   G  V            +  W  + K 
Sbjct: 8964 NSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKP 9023

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +K   + + S    +A+L I K + + AG Y     N  G A     + + +  +PP   
Sbjct: 9024 LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 9083

Query: 1388 -NILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLK 1444
              +  +D+        E   TG   I + +  + +EI +     +  +  +   ++  + 
Sbjct: 9084 IRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVD 9143

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
               S ++  YAVNEV     +        IKE  I     ++  + +        +L   
Sbjct: 9144 KGDSGQYTCYAVNEVGKDSCTAQLN----IKERLIPPSFTKRLSETVEETEGNSFKLEGR 9199

Query: 1505 FGGVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE 1560
              G     V WY++  +++     + T++N                 Y C   ND G   
Sbjct: 9200 VAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL 9259

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
             +  + I++     + ++ +        E++ ++  ++G  P  + W K G +++     
Sbjct: 9260 CTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRC 9319

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            + +    T+V+ ++++ ++ S  Y  +ASN AG+ + +  + + DKP+
Sbjct: 9320 SFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPA 9367



 Score =  218 bits (533), Expect = 1e-54
 Identities = 225/903 (24%), Positives = 364/903 (40%), Gaps = 84/903 (9%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            VEK        G T   EC V G P     WF+    +     +++ + +  V+ L I  
Sbjct: 8516 VEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFN-KVSGLKIIN 8574

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
            V P D+G ++   +N  G  S T  L V        S+ TV                   
Sbjct: 8575 VAPSDSGVYSFEVQNPVGKDSCTASLQV--------SDRTV------------------- 8607

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F++K K      GS +++EC++   P   ++W  +G EI         +  +    C
Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT---C 8664

Query: 693  SVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            + L +  +++   G YT +A N  G  E S P+ +      +EPP  ++    M V  G 
Sbjct: 8665 A-LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV------REPPSFVQKPDPMDVLTGT 8717

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808
            +V  ++ V G P  +++W K +  +      +     S+  L+   V     G YT    
Sbjct: 8718 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 8777

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G A  +  + ++ P +       F+ R  + ++++   + L    T  P  S+TW +
Sbjct: 8778 NEAGKASCTTHLYIKAPAK-------FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKK 8830

Query: 869  NNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            N   ++PS+   IT       +E+  + V+   D+G Y C   N++GK S  A++ I +E
Sbjct: 8831 NGINVTPSQRCNITTTEKSAILEIPSSTVE---DAGQYNCYIENASGKDSCSAQILI-LE 8886

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
               FVK L+   +   G +  L+CQ + T  +   WY    ++      ++         
Sbjct: 8887 PPYFVKQLE-PVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945

Query: 985  XXXXXXXXDVGVIKC----IVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEV 1038
                    D G   C     V +   ST L V+E    P F R+L+D +       + + 
Sbjct: 8946 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC 9005

Query: 1039 EIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRD 1093
             I+ SE   V W +DG+ +K   N        +   L I  T     G+YSC     +  
Sbjct: 9006 AISGSEPISVSWYKDGKPLKDSPN-VQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 9064

Query: 1094 ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
             S +A + + E   PP    RL       G  A FE  +T    + V W KD  EI+   
Sbjct: 9065 ASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGG 9124

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLPE 1204
              Q++       L +   D  D+G+Y+C    EVG   CTA L ++E  I  +FT RL E
Sbjct: 9125 KYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSE 9184

Query: 1205 FILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             +         L   +   + + V WYK    I+ T    +        L +RK   +D 
Sbjct: 9185 TVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDA 9244

Query: 1264 CEYTC-VLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319
              YTC V  DA S   T+ + ++  + PP    +     +  G  V L    Q       
Sbjct: 9245 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRI 9304

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +W+   + IK       S  S +A L ++ V   D+G Y  +  N  G    +  VTI D
Sbjct: 9305 QWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKD 9364

Query: 1380 KPS 1382
            KP+
Sbjct: 9365 KPA 9367



 Score =  217 bits (531), Expect = 2e-54
 Identities = 198/748 (26%), Positives = 332/748 (44%), Gaps = 48/748 (6%)

Query: 1337  SIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD--VEMNVTILDK---PSPPGKPNILE 1391
             S  +K+     K +E  D  I+++  EN  G +D  V  ++   D+   P  P +P + E
Sbjct: 17891 SASAKTTCKVSKLLEGKDY-IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17949

Query: 1392  IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT---KTQTSIQNLKTNSS 1448
             +   S  + W++P + G   I  Y++E +E  +  W  V        T+  + +L     
Sbjct: 17950 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 18008

Query: 1449  YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI---- 1504
             Y FR  A NE+ I D S  ++   V  +  I  P+     + I T  N  ++LT      
Sbjct: 18009 YEFRVSAENEIGIGDPSPPSK--PVFAKDPIAKPSPPVNPEAIDTTCNS-VDLTWQPPRH 18065

Query: 1505  FGG--VPQPKVTWYRDG-KKLKTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHGEV 1559
              GG  +    V + + G ++ + A  T E+                YK   +A N  GE 
Sbjct: 18066 DGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES 18125

Query: 1560  ETSCV---VGIQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             + + V   V ++ +   P + +     +++H KVGD   ++A+I+G+P P+V W K    
Sbjct: 18126 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 18185

Query: 1613  LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                    ++T     S + I+         Y++   N AG+ +V V + V DKP  P   
Sbjct: 18186 APTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR-D 18242

Query: 1673  VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732
             + + EI ++S  + WK PLDDGG  +T Y +E+ +  + +W  ++   +  +++  + LN
Sbjct: 18243 LEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKHLN 18301

Query: 1733  ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFP 1790
             E  +Y+FRV A+N  G    +E+ P  IK ALD   P           +D   V + W  
Sbjct: 18302 EGNQYLFRVAAENQYGRGPFVET-PKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 18359

Query: 1791  SEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL 1849
              +++GGSPI  Y VE ++EG + W            +  L    TY+FR+ A N +G  L
Sbjct: 18360 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGL 18419

Query: 1850  PYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
             P T+   I   + L PPS   +  + E        T+++         P   +  +   +
Sbjct: 18420 PDTT-IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI 18478

Query: 1908  KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
             K      + T   S     I+N   +D   ++I+  N  G    +++ +V L     VP 
Sbjct: 18479 KTDEHYTVETDNFS-SVLTIKNCLRRDTGEYQITVSNAAG----SKTVAVHLTV-LDVPG 18532

Query: 1968  PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027
             PPT P+ I  V    +  SW  P+ DGG+P++ Y +  +D  K  W  V      T K  
Sbjct: 18533 PPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKT-KLK 18591

Query: 2028  IRDLSENHTYMIRIYARNEIGLSEPLES 2055
             I  L +   Y+ R+ A N+IG+  PL+S
Sbjct: 18592 IPHLQKGCEYVFRVRAENKIGVGPPLDS 18619



 Score =  217 bits (531), Expect = 2e-54
 Identities = 170/693 (24%), Positives = 291/693 (41%), Gaps = 26/693 (3%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
             P PP  P +++    SI++ W +P   G + I+ YV+E QE DT +W  V     I  T+
Sbjct: 30269 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 30328

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPN 1496
              ++ +LK    Y FR  AVN   +S+ SE+    + ++  +I    +   LK  +T    
Sbjct: 30329 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 30388

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
               + L     G P P +TW + G  L +     T E+                Y   A N
Sbjct: 30389 ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAEN 30448

Query: 1555  DHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
               G+   + +V +   P    ++  +++  +  V   W +  +  G P    I  K    
Sbjct: 30449 QSGKKSATVLVKVYDTPGPCPSVKVKEVS-RDSVTITWEIPTIDGGAPVNNYIVEKREAA 30507

Query: 1613  LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             +   K   +TTK   ++ RI  L       + +   N  G      T         P  P
Sbjct: 30508 MRAFK--TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVP 30565

Query: 1673  VIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730
               +   ++++ +VT+ W+ PL DGG  LT Y +E  +    RW+KV  +   V  + +  
Sbjct: 30566 AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 30625

Query: 1731  LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDNESVYITWF 1789
             LNE  +Y+FR+ AQN  G SE  E+   V    L V P+          I   +      
Sbjct: 30626 LNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVEL 30685

Query: 1790  PSEKNGGSPIID---YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
                  G  P      +     +E ++             I++ +I  T ++ +  +N  G
Sbjct: 30686 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 30745

Query: 1847  TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
             T+   +   K+ I     PP+ P    + E  + S+T+ W  PE +GG+P++ Y++E + 
Sbjct: 30746 TT---SETIKVIILDKPGPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 30800

Query: 1907  VKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965
                  W  +  +V  S  +     + E +E +FR++A N  G+    +S+ +       +
Sbjct: 30801 AHRPGWLPVSESVTRSTFK--FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 30858

Query: 1966  PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
             P PP   L+I  V  + +  +W  PE DGG+ + GY +  ++V    W+ V KV V   +
Sbjct: 30859 PGPPET-LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 30917

Query: 2026  FNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             +    L+E   Y  R+ A N  G  +P    +P
Sbjct: 30918 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30950



 Score =  217 bits (530), Expect = 3e-54
 Identities = 236/1040 (22%), Positives = 413/1040 (39%), Gaps = 74/1040 (7%)

Query: 1105  LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
             LPP+I+   Q   +  G K   E  +  K     +W K   E+  S+H+ +        L
Sbjct: 19825 LPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 19883

Query: 1164  KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDAY-LTVEIP 1221
              I D    D+G YS    NS  T    ++   ++      P F +   + DA  L+  IP
Sbjct: 19884 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19943

Query: 1222  --DETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AK 1274
               D   ++T Y  +K  +   +  T ++ V K +  + K     +  +     +    ++
Sbjct: 19944 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 20003

Query: 1275  STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
               T  K+ V +FP  +    +  R+ + +   + V +          I+   I +K +++
Sbjct: 20004 PLTSPKM-VAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNS 20062

Query: 1335  KPSIDSKSASLTIKKVENTDAGI-----YKLRLE--NNCGHADVEMN---VTILDKPSPP 1384
                +  K+    ++  E   AG+     Y  R+   N  G +        VT      PP
Sbjct: 20063 LLWV--KANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPP 20120

Query: 1385  GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKTQTSI 1440
             GKP ++++  S++++ W  P++ G S II Y VE  ++   +W+        I + + + 
Sbjct: 20121 GKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA 20180

Query: 1441  QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDI 1499
               L+  + Y+FRA A   V+IS  SE ++   ++ E       +   +K++ T +   ++
Sbjct: 20181 TGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNV 20240

Query: 1500  ELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
              L     G P P V+W +DG  LK A+    A   N                Y   A N 
Sbjct: 20241 CLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENS 20300

Query: 1556  HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
              G    +  + +  KP    S   +K      D     A++   PP E    +  N + +
Sbjct: 20301 SGSKSATIKLKVLDKPGPPAS---VKINKMYSDR----AMLSWEPPLEDGGSEITNYIVD 20353

Query: 1616  DKEYN------ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYD 1664
              +E +      ++     +   +++L   H  ++ I A N  G      +   +    YD
Sbjct: 20354 KRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYD 20413

Query: 1665  KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
              P + + PVI   I+++ +T+ WKPP DDGG  +T Y +EK E     W KV        
Sbjct: 20414 PPGRCDPPVISN-ITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIER 20472

Query: 1725  TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             T     L E  EY FRV A N  G  +  ++           P               SV
Sbjct: 20473 TLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSV 20532

Query: 1785  YITWFPSEKNGGSPIIDYKVEIKQ-EGKKW---KXXXXXXXXXARIQKLSINTTYQFRIY 1840
              ++W     +GGSPII Y VE+K+ +   W               +  L  +T YQFR+Y
Sbjct: 20533 SLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVY 20592

Query: 1841  ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPIT 1898
             A N+IG S P    DK      L PP    +  + ++      VT++   P      P  
Sbjct: 20593 AVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKI 20652

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
              +      ++ +    I +        C EN+ + D   + ++ EN+ G     + +   
Sbjct: 20653 TWSKPNVNLRDRIGLDIKSTDFDTFLRC-ENVNKYDAGKYILTLENSCG-----KKEYTI 20706

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
             + K    P PP   + ++ +  +    +W  P  DGG+P++ Y +  RD  +  W  V  
Sbjct: 20707 VVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-T 20764

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078
              + +   F + +L E  +Y  R++A NE G+ +P E+ +  K        A + PG   +
Sbjct: 20765 TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVK--------ASQTPGPVVD 20816

Query: 2079  VXXXXXXXXXXXXXWLREHN 2098
             +             W + H+
Sbjct: 20817 LKVRSVSKSSCSIGWKKPHS 20836



 Score =  217 bits (529), Expect = 4e-54
 Identities = 266/1201 (22%), Positives = 467/1201 (38%), Gaps = 92/1201 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F++K+    T   S+  F+  V G P   ITW +         D Q+  +DDNV    
Sbjct: 5975 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLK---------DDQILDEDDNVYI-- 6023

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
                                 F  S   L + +  + H    T             A +L
Sbjct: 6024 --------------------SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 6063

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
               P    +K K+  V E   + LEC +   PE  + WL  G++IVP    S++ E+++ 
Sbjct: 6064 VQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 6123

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             +    +I +V K   G YT    N  G +S    L++   +  PP   + L  M    G
Sbjct: 6124 SF----RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV-LDQNIPPSFTKKLTKMDKVLG 6178

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKA 807
             S+ +  +V G+   +  W K+ K +  +   +      S+++ +   +++D   YT K 
Sbjct: 6179 SSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 6238

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G    S ++TV+EP     +P     R Q I      T++  A +   P   I W+
Sbjct: 6239 SNVAGDDACSGILTVKEPPSFLVKP----GRQQAI---PDSTVEFKAILKGTPPFKIKWF 6291

Query: 868  RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            +++ E++S  +      +G    L + +VD+   +G Y C  +N  G  S    + +  E
Sbjct: 6292 KDDVELVSGPKCFI-GLEGSTSFLNLYSVDAS-KTGQYTCHVTNDVGSDSCTTMLLV-TE 6348

Query: 927  KVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
               FVK L+ S   + G +  LEC+   S  +   W+ N+ E+   D   +         
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI 6408

Query: 985  XXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                    D G   C  ++       ST ++VKE  P F       E  +     LE E+
Sbjct: 6409 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP-PVFSSFPPIVETLKNAEVSLECEL 6467

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
            + +   +VVW +D   ++  K KY    +     ++I N    D GEY C  ++E    +
Sbjct: 6468 SGTPPFEVVWYKDKRQLRSSK-KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDT 6526

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE-IQFSNHIQ 1153
            C   V + E PP  +++L +  V  G  A  +  +     + V+W K+  E I+ S +I+
Sbjct: 6527 CVCTVKLKE-PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIR 6585

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209
            +T       L+    +  +AG+Y C++    G  +  A L V EP++      P  + V 
Sbjct: 6586 ITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVG 6645

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                    V    E L V WYK   ++  ++K       K  +L I      D   YT  
Sbjct: 6646 ETCTLECKVAGTPE-LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQ 6704

Query: 1270 LLD--AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324
            + +   KS+    V+V +   PP      +      G+   L          +  W    
Sbjct: 6705 VQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEK 6764

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
            +KI+   K+ + +      +L +  ++++D G Y     N  G  +    +T+ + PS  
Sbjct: 6765 TKIVSGAKY-QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFV 6823

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNL 1443
             +P  LE+     N+ +           + +    +E+   +  ++    T  +  + N+
Sbjct: 6824 KEPEPLEVLPGK-NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNI 6882

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
              + S  +     N  +   AS TT  +  +KE         K L + + EP + I L  
Sbjct: 6883 DISQSGEYTCVVSN--NAGQASCTTRLF--VKE----PAAFLKRLSDHSVEPGKSIILES 6934

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             + G     VTW +DG  + T++     T E                 Y C   N+ G  
Sbjct: 6935 TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRD 6994

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                +V   + P      E ++    VGD   +   + G P   V WYK   KL    EY
Sbjct: 6995 VCGALVSTLEPPYFVTELEPLEA--AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEY 7052

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
                    + +   ++  + S +YT +A N+ GT+S +   ++ ++   P     +++I 
Sbjct: 7053 RTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIE 7112

Query: 1680 R 1680
            +
Sbjct: 7113 Q 7113



 Score =  215 bits (525), Expect = 1e-53
 Identities = 135/442 (30%), Positives = 209/442 (47%), Gaps = 13/442 (2%)

Query: 1626  KTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISR 1680
             K +  R+K L      ++ + A N AG      S+  + +K    P  P G   ++++ +
Sbjct: 14865 KDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGK 14924

Query: 1681  ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
              SV + W  P  DGG ++  Y IE  +   + W++VA+     + + +  L E  EY FR
Sbjct: 14925 TSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQ-HLLPGLMEGQEYSFR 14983

Query: 1741  VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             V A N  G SE  E S+P++ +  L  PS            N +  + W   EK+GGSPI
Sbjct: 14984 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKN-TADLKWTVPEKDGGSPI 15042

Query: 1800  IDYKVEIKQEGKK-WKXXXXXXXXX-ARIQKLSINTTYQFRIYARNEIGTSLPYTS-DDK 1856
              +Y VE +   +K W+            +  L+  + Y FR+ A N IG S  YT  +D 
Sbjct: 15043 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQS-DYTEIEDS 15101

Query: 1857  ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
             +    T T P  P    V + T R V LKW  P+++GG PI  Y+IE K   G  W K  
Sbjct: 15102 VLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG 15161

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
                G      + ++ E  E+ F++ AEN  GV  P+E   +   +  T P  P   L + 
Sbjct: 15162 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 15221

Query: 1977  MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD-LSENH 2035
               G   +  +W  PE +GG+P++GY++ +  V    WM V    +  LKF + + +  + 
Sbjct: 15222 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 15281

Query: 2036  TYMIRIYARNEIGLSEPLESDE 2057
              Y++R+ A N IG+SEP E  E
Sbjct: 15282 EYVLRVRAVNAIGVSEPSEISE 15303



 Score =  215 bits (525), Expect = 1e-53
 Identities = 213/871 (24%), Positives = 352/871 (40%), Gaps = 56/871 (6%)

Query: 1228  TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVE 1285
             +W K    I  ++   + S      L I+  T  D  EYT    +   T    +KV V++
Sbjct: 21339 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD 21398

Query: 1286  FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
              P      E        + +T     +    P   +I+  +   +   T  S D +S   
Sbjct: 21399 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 21458

Query: 1346  TIKKVENTDAGIYKLRLENNCGHADVEMN--VTILDK---PSPPGKPNILEIDSSSINIC 1400
                K+   +  I+++   N+ G  +   +  V ++D+   P PP KP +  +  ++  + 
Sbjct: 21459 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 21518

Query: 1401  WDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             W  P + G S I  Y VE +E  +  W+ ++K  ++  +  +  L+  S+Y FR  A N 
Sbjct: 21519 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 21578

Query: 1459  VDISDASETTEYYKVIKETKIQSP--------TVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
               I   SE ++   +        P        T +K       +P+ D  L      V  
Sbjct: 21579 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 21638

Query: 1511  PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQ 1568
              KV    D   +K    T                   ++  A ND G  E + +  V I 
Sbjct: 21639 QKVG---DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 21695

Query: 1569  QKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
             ++ +      D + +     + G    +   I+G P PEV W K+   L+N    NI   
Sbjct: 21696 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENT 21753

Query: 1625  EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MR--EISRE 1681
             E  +++ I E  R  + K+ +   N AG  S  V ++V D P    GPV+ +R  +I+++
Sbjct: 21754 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTP----GPVLNLRPTDITKD 21809

Query: 1682  SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
             SVT+ W  PL DGG  +T Y +EK E     +   A       TY +  L+E CEY FRV
Sbjct: 21810 SVTLHWDLPLIDGGSRITNYIVEKREATRKSY-STATTKCHKCTYKVTGLSEGCEYFFRV 21868

Query: 1742  IAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
             +A+N  G  E  E+ EP+    A   P           I   +V + W   + +GGS I 
Sbjct: 21869 MAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD----ITKSTVSLAWPKPKHDGGSKIT 21924

Query: 1801  DYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
              Y +E +++G  +W            ++ L+    Y F++ A N  G S P  S   I  
Sbjct: 21925 GYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 21984

Query: 1860  GKTLTPPSQPRNFVVSESTSRSV-TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
              +T+ P    R        +++   +K   P      P   +    + +K        T 
Sbjct: 21985 EQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETT 22044

Query: 1919  GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
               S   +  E ++  D   + ++A N VG         + ++ H  +P PPT P++   V
Sbjct: 22045 ATSTILNINECVRS-DSGPYPLTARNIVG----EVGDVITIQVH-DIPGPPTGPIKFDEV 22098

Query: 1979  GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
              S+ V  SW  PE DGG P+  Y + +R    T W+E+    + T  +    L+    Y 
Sbjct: 22099 SSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT-TYKATRLTTGLEYQ 22157

Query: 2039  IRIYARNEIGLSEPLES-----DEPFKVIPG 2064
              R+ A+N  G+   + S     + PFKV PG
Sbjct: 22158 FRVKAQNRYGVGPGITSACIVANYPFKV-PG 22187



 Score =  213 bits (521), Expect = 3e-53
 Identities = 239/1100 (21%), Positives = 425/1100 (38%), Gaps = 56/1100 (5%)

Query: 596  TELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD--ILEGIPPTFSKKPKAQYVDEGSDILL 653
            T +I +    DH  E               A   +++   P   +K +   V  G     
Sbjct: 4343 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKF 4402

Query: 654  ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
             C + + P     W   G EI   +  S+        Y S L+I   +    G YT  A 
Sbjct: 4403 TCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK----YISSLEILRTQVVDCGEYTCKAS 4458

Query: 714  NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
            N  G  S    L +   E  PP  +   KS+    G++      V G P     W K+  
Sbjct: 4459 NEYGSVSCTATLTVT--EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 4516

Query: 774  PVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             +   P    SD +   I  L    ++D GVY+ KA N  G     A + +        +
Sbjct: 4517 ALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII-------ID 4569

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
             P FI   + +       + L  +V  +   ++TW ++ + + P +     F+ +   L 
Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 4629

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
            I     + DSG Y C ASN AG SS  A VT+  E  +FVK +  SY    G++  L C+
Sbjct: 4630 IPLAKLK-DSGTYVCTASNEAGSSSCSATVTVR-EPPSFVKKVDPSYLMLPGESARLHCK 4687

Query: 952  T--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKD---QE 1005
               S  +   W+ N KE+S  +   +                 D G   C  V D     
Sbjct: 4688 LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDS 4747

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYD 1064
             ST +V+KE  P FI+ L+  ++     A+L+ E++ +   ++ W +D + I+  K KY 
Sbjct: 4748 CSTEIVIKEP-PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-KYR 4805

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVT-VVELPPEIITRLQNQKVNKG 1121
               +  +  L I + +  D GEY C++ +E   C    T +++ PP  + ++ +     G
Sbjct: 4806 LFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGG 4865

Query: 1122 NKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
               T +  +   + + V W K    I+    I+++       L I D  +   G+Y+C  
Sbjct: 4866 QTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLA 4925

Query: 1179 --EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235
              E G+      L V+EP+    +   E I V A   A L   +     L   WYK    
Sbjct: 4926 ENEAGSQTSVGELIVKEPA--KIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4983

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295
            +  ++K+ +        L        D  +YT  + +   ++  +         I  +  
Sbjct: 4984 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFT 5043

Query: 1296 EYRIKRGSDV--TLLVDYQ-AFPQP-NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            +      S V  T  +D + A   P    W  + K I      + +    +ASL I +V+
Sbjct: 5044 KPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVD 5103

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              DAG +  R  N+ G  D    + + + PS   KP   ++   S        + +   T
Sbjct: 5104 MNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLT 5163

Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
            I ++    + +        K   ++   +  +KT+ S  +     N     + S      
Sbjct: 5164 IRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL--- 5220

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----A 1527
              +KE    +  VEK   +   +  +  +L C   G P  K+TW+ + +++K +     +
Sbjct: 5221 -FVKE---PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS 5276

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
              E+                Y C A N+ G    S +V +++ P  T   + I+   +  
Sbjct: 5277 FVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY- 5335

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
             + ++ A + G PP E+ W+K+   L + ++Y    ++    ++I +   + + +Y    
Sbjct: 5336 -DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRV 5394

Query: 1648 SNTAGTSSVEVTLKVYDKPS 1667
            +N  G+S     + + + PS
Sbjct: 5395 TNEVGSSICSARVTLREPPS 5414



 Score =  213 bits (521), Expect = 3e-53
 Identities = 206/899 (22%), Positives = 374/899 (41%), Gaps = 44/899 (4%)

Query: 1186  TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTL 1244
             T I +   P I+  L   E +   A T   L   I  +    + WYK    ++      +
Sbjct: 27789 TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV 27848

Query: 1245  ISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
              +     +++I+     +   Y   L +A   ++  ++V++++ P        E++    
Sbjct: 27849 ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGP-PGGPIEFKTVTA 27907

Query: 1303  SDVTLLVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
               +TLL    A         +IV  +   +   +  S   +   +T  K+   +  I+++
Sbjct: 27908 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRV 27967

Query: 1361  RLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
             R  N  G  +   + +++ K     P PPG P + +I  +S+ + W  P   G S I  Y
Sbjct: 27968 RAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY 28027

Query: 1416  VVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
              +E ++  +  W  V  + I  T+  +  L  NS Y++R  AVN       SE +E+YK 
Sbjct: 28028 FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKA 28087

Query: 1474  IKETKIQSPTVEKPLKNITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLK--TAKATY 1529
                     P  +  + + T           ++  G      V   R G++ +  T     
Sbjct: 28088 ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKG 28147

Query: 1530  ENRXXXXXXXXXXXXXXXY-KCIAFNDHGEVE-TSCVVGIQQKPVITISNEDIKQK---- 1583
             E R               Y +  A N  G+ E       +Q K ++     D+       
Sbjct: 28148 EVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTS 28207

Query: 1584  --HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                K G++  V    +G PPP V W K+   L +D  Y+I   + +S++ I ++ R+ + 
Sbjct: 28208 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 28267

Query: 1642  KYTIEASNTAG-TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
             KY +   N  G   S  V++KV D P+  +  + ++ +SR +VT+ W PPL DGG  +  
Sbjct: 28268 KYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRGTVTLLWDPPLIDGGSPIIN 28326

Query: 1701  YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759
             Y IEK +     W  V        ++ +  L+E   + FRV+A+N +G  E  E +EP+ 
Sbjct: 28327 YVIEKRDATKRTW-SVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPV- 28384

Query: 1760  IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXX 1818
                A +VP+              SV ++W   + +GGS I +Y VE K +G++ W     
Sbjct: 28385 --KAAEVPAPIRDLSMKDS-TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI 28441

Query: 1819  XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                    + +L   +  +FR++A+NE G S P T          +TP     +   ++ T
Sbjct: 28442 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 28501

Query: 1879  SR-SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
              R    +    P      P  +++ +   +K   + +       +    I+N K++    
Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGK 28560

Query: 1938  FRISAENTV-GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996
             + +  +N V  +++P    ++        PS P  P+    + ++ V+ SW  PE +GG 
Sbjct: 28561 YTVILDNAVCRIAVPITVITL------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGG 28614

Query: 1997  PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              +  Y+I  R+ ++T W  V    V    F + +L ++  Y  R+ A N  G+S+PL S
Sbjct: 28615 EITCYSIEKRETSQTNWKMVCS-SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 28672



 Score =  213 bits (520), Expect = 4e-53
 Identities = 228/896 (25%), Positives = 367/896 (40%), Gaps = 72/896 (8%)

Query: 1204  EFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
             + + + A +D  L   +  +    + W K    ++  EK +L    K+ T +I+ C   D
Sbjct: 29982 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 30041

Query: 1263  QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-- 1320
               +YT  + +A  T  + V V     K++D          S VT      A+  P ++  
Sbjct: 30042 SGKYTLTVKNASGTKAVSVMV-----KVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG 30096

Query: 1321  -----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMN 1374
                  +IV  +   +        +  + S  + ++   +  I+++R  N  G    VE  
Sbjct: 30097 AEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESE 30156

Query: 1375  VTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
               +       PSPPG P  +      I I W +PE+ G + I  Y+V+ +E  +  W  V
Sbjct: 30157 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 30216

Query: 1431  KN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP----- 1482
                  +  T+  + +L     Y+FR  AVN    S+ SE + +    + +    P     
Sbjct: 30217 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR 30276

Query: 1483  ---TVEKPLKNITTEPNEDIELTCIFGGV--PQPKVT--WYRDGKKLKTAKATYENRXXX 1535
                T +  +    T+P  D   T I G V   Q K T  WYR         AT  N    
Sbjct: 30277 VVDTTKHSISLAWTKPMYDGG-TDIVGYVLEMQEKDTDQWYR-----VHTNATIRN-TEF 30329

Query: 1536  XXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKV--GD 1588
                         ++  A N  G  E S  +  I+    I I +    +D+K+   +  G 
Sbjct: 30330 TVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGA 30389

Query: 1589  EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
                +   + G PPP + W K G  L +     I T E  S++ + ++ R  + KYTIEA 
Sbjct: 30390 SLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAE 30447

Query: 1649  NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
             N +G  S  V +KVYD P  P   V ++E+SR+SVTI W+ P  DGG  +  Y +EK E 
Sbjct: 30448 NQSGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREA 30506

Query: 1709  DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768
                R  K          Y I  L E   Y FRV+ +N  G  E  E+   V+ +  +VP 
Sbjct: 30507 AM-RAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVS--EVP- 30562

Query: 1769  XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ 1827
                       +   +V + W     +GGS +  Y +E  + G ++W              
Sbjct: 30563 LVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHT 30622

Query: 1828  KLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGK-----TLTPPSQPRNFVVSESTSR 1880
               S+N    Y FRI A+NE G S P  +   +T+       T+   + P+   +     R
Sbjct: 30623 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK-TIHVPAGR 30681

Query: 1881  SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
              V L    P +    P  ++      ++ +S    V     V +  I     +D   + +
Sbjct: 30682 PVEL--VIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGEYTL 30738

Query: 1941  SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
               +N  G +  T  + + L+K    P PPT P++I  + +  +  SW  PE DGGAPL G
Sbjct: 30739 ELKNVTGTTSET-IKVIILDK----PGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 30793

Query: 2001  YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
             Y +  RD  +  W+ V +  V    F    L+E + Y+ R+ A N  G+   L+S+
Sbjct: 30794 YVVEQRDAHRPGWLPVSE-SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSE 30848



 Score =  208 bits (508), Expect = 1e-51
 Identities = 225/926 (24%), Positives = 383/926 (41%), Gaps = 55/926 (5%)

Query: 1161  QKLKIYDCDLDDAG--EYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
             Q+ KI  C L+  G  E +   G  K    L  E P ++    L + I+V A   A + +
Sbjct: 24916 QEYKIRVCALNKVGLGEATSVPGTVKPEDKL--EAPELDLDSELRKGIVVRAGGSARIHI 24973

Query: 1219  EIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
                   T ++TW +++   E T+K  +   V    L I  C  +D  +Y   L ++  + 
Sbjct: 24974 PFKGRPTPEITWSREEG--EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK 25031

Query: 1278  K--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
                + V+V++ P       +   +K     +  + ++  P  +    V + +I K + T+
Sbjct: 25032 SAFVTVKVLDTPGP----PQNLAVKEVRKDSAFLVWEP-PIIDGGAKVKNYVIDKRESTR 25086

Query: 1336  PSIDSKSA--SLTIKKVEN-TDAGIYKLRL--ENNCG-HADVEM--NVTILDKPSPPGKP 1387
              +  + S+  S T  KVEN T+  IY  R+  EN  G    VE    V   + PSPPGK 
Sbjct: 25087 KAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKV 25146

Query: 1388  NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
              + ++  +S ++ W++PE+ G S ++ YVVE Q   T +W  V         +  L +  
Sbjct: 25147 TLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQ 25206

Query: 1448  SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
              Y+FR  A NE   SD         + K+  IQ P+++ P    + +  ED+++     G
Sbjct: 25207 EYQFRVKAYNEKGKSD-PRVLGVPVIAKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIG 25264

Query: 1508  VPQPKVTWYRDGKKLK-TAKATYENRXXXX---XXXXXXXXXXXYKCIAFNDHGEVETSC 1563
              P+P ++W +DG+ LK T +   E                    Y   A N  G    + 
Sbjct: 25265 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 25324

Query: 1564  VVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
              V + +K   PV  +  +++     V   W   A   G      I  K           +
Sbjct: 25325 SVIVLEKPGPPVGPVRFDEVSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 25383

Query: 1621  ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMR 1676
              T    T  I+I +LK     ++ I A N  G S    S  V ++   K   P G   + 
Sbjct: 25384 ATVARTT--IKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVT 25441

Query: 1677  EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
              IS++ + ++W  P++DGG ++  Y +E+ E ++  W+K+         +    L+E  E
Sbjct: 25442 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 25501

Query: 1737  YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
             Y F+V A+N VG  +  + SE  V +   D P           I   +V + W     +G
Sbjct: 25502 YEFKVSAENIVGIGKPSKVSECFVARDPCDPPG----RPEAIVITRNNVTLKWKKPAYDG 25557

Query: 1796  GSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPY 1851
             GS I  Y VE K   +G+  K            +  L  +  Y+FR+ ARN  G  S P 
Sbjct: 25558 GSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS 25617

Query: 1852  TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
              S   IT    +  P+   +    +         +       G PI + +      + + 
Sbjct: 25618 DSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 25677

Query: 1912  WTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969
                 + +  ++ +    +++    D   + +   N  G    T+S  + + K    P PP
Sbjct: 25678 TAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG----TKSIPITV-KVLDRPGPP 25732

Query: 1970  TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029
               PL++  V +     +W  P  DGGA +  Y I  R+ ++  W +V   +V  L + + 
Sbjct: 25733 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV-STEVQALNYKVT 25791

Query: 2030  DLSENHTYMIRIYARNEIGLSEPLES 2055
              L   + Y+ R+ A N+ G+ EPLES
Sbjct: 25792 KLLPGNEYIFRVMAVNKYGIGEPLES 25817



 Score =  208 bits (507), Expect = 2e-51
 Identities = 223/960 (23%), Positives = 396/960 (41%), Gaps = 70/960 (7%)

Query: 750   ESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
             + VIL  ++     P + W K+ K   P K    K+DG    + ILK     D G YT  
Sbjct: 12960 DEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRML-ILKKALKSDIGQYTCD 13017

Query: 807   AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
                  G  +TS  + +E+   +   P         + V E  T +    ++ + + +  W
Sbjct: 13018 C----GTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISEDDIHA-NW 13066

Query: 867   YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
                 E +  +       +G+   LV+ N   +  +G     A+N   KSS   RV   V 
Sbjct: 13067 KLKGEALLQTPDCEIKEEGKIHSLVLHNCRLD-QTGGVDFQAANV--KSSAHLRVKPRV- 13122

Query: 927   KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
              +  ++ L K      G+T   +C+ S+  +  +WY   K++   D      EG+     
Sbjct: 13123 -IGLLRPL-KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLT 13180

Query: 986   XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                    D G ++   KD +T   L VKE   EF + L+D  V+E   A+LE E++ E A
Sbjct: 13181 LRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENA 13240

Query: 1046  DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W ++G EI+K KK  Y+    G +RKL I + +  D   Y+C  +D   +  + VV 
Sbjct: 13241 KVKWFKNGTEILKSKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP 13298

Query: 1105  LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
                E +  L + +V +   A FE EL++ +A V+WFKDG+EI+      +   G  + L 
Sbjct: 13299 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 13358

Query: 1165  IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
             I  C LDD  EYSCEV  ++ + +LTV E    FT  L   I V       L  E+    
Sbjct: 13359 INKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLAN-IEVSETDTIKLVCEVSKPG 13417

Query: 1225  LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              +V WYK    I +T ++ ++++ +KR L+I+    +D   Y C L    S T  KV+V 
Sbjct: 13418 AEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL--PSSRTDGKVKVH 13475

Query: 1285  EFPPKIVDYEREYRIKRG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
             E   + +   +   I  G  ++    +  ++FP    +W  + K ++         D K 
Sbjct: 13476 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPV---QWKRDDKTLESGDKYDVIADGKK 13532

Query: 1343  ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINIC 1400
               L +K     D G Y + +    G A    ++T+++K     P K   ++     +  C
Sbjct: 13533 RVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNC 13588

Query: 1401  WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
                  NT  +   ++  E    D++++I ++        I++   +    +     N   
Sbjct: 13589 ---EVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 13645

Query: 1461  ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
              +  S       +++E  ++   + +PLK+I T   + +   C    +    + W ++G+
Sbjct: 13646 ENVKSAAN---LIVEEEDLR---IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGE 13698

Query: 1521  KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNE 1578
             ++      ++NR                K   F D GE  V       + +  +I    E
Sbjct: 13699 EV-----PFDNR--VSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTE 13751

Query: 1579  DIKQKHKVGDEWLVTAVIE---GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
              ++            AV           V WY+NG +++  K+Y          + IK+ 
Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDC 13811

Query: 1636  KRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSK-PEGP----VIMREISRESVTIEW 1687
             +     +Y     +    + +   E+ +++   P    E P    V + E++++ V ++W
Sbjct: 13812 RLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQW 13871



 Score =  205 bits (501), Expect = 9e-51
 Identities = 229/937 (24%), Positives = 390/937 (41%), Gaps = 70/937 (7%)

Query: 1157  DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
             + ++ K++IY  + +  GE +   G  K    +   E  ++  LR  + + + A     L
Sbjct: 22750 ENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLR--KVVTIRACCTLRL 22807

Query: 1217  TVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
              V I      +V W +     E  +K ++ S      LI+      D  +Y   + ++  
Sbjct: 22808 FVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 22865

Query: 1276  TTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
             +    + V V++ P    D + +   K  + VTL  D    P  +    + + I++K + 
Sbjct: 22866 SKSAFVNVRVLDTPGPPQDLKVKEVTK--TSVTLTWDP---PLLDGGSKIKNYIVEKRES 22920

Query: 1334  TKPSIDSKSASL--TIKKVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSPPG 1385
             T+ +  + + +   T  KV+    G    +++  EN  G    A+   +V   ++P PPG
Sbjct: 22921 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22980

Query: 1386  KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
             K  ++++  +S+++ W++PE+ G S I+ Y+VE Q   + +W +   +  T+ +I  L  
Sbjct: 22981 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQ 23040

Query: 1446  NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
                Y FR  A NE  ISD  + +    VI +  +  P  +      T    ED+++   F
Sbjct: 23041 GEEYSFRVSAQNEKGISDPRQLS--VPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPF 23098

Query: 1506  GGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P P VTW++D   LK      A++T EN                Y     N  GE  
Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAEST-ENNSLLTIKDACREDVGHYVVKLTNSAGEAI 23157

Query: 1561  TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN----D 1616
              +  V +  KP        +K      DE    ++     PP+   Y  G+ + N     
Sbjct: 23158 ETLNVIVLDKP--GPPTGPVKM-----DEVTADSITLSWGPPK---YDGGSSINNYIVEK 23207

Query: 1617  KEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYD-KP 1666
             ++ + TT +  S       I+   LK     ++ I A N  G S+    E T+  Y  K 
Sbjct: 23208 RDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 23267

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
               P G  ++   SR+S+ ++W  P+ DGG  +  Y +E+ E ++  W+K+         +
Sbjct: 23268 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKF 23327

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
                 L E  EY FRV A+N VG  +  + SE  V +   D P           +   SV 
Sbjct: 23328 KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPG----RPEAIIVTRNSVT 23383

Query: 1786  ITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXX-XXXXXXXARIQKLSINTTYQFRIYAR 1842
             + W     +GGS I  Y VE K+  EG+  K            +  L  +  Y+FR+ AR
Sbjct: 23384 LQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIAR 23443

Query: 1843  NEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             N  G  S P  S   IT    + PP    +    ++        +       G PI   I
Sbjct: 23444 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-I 23502

Query: 1902  IEFKTVKGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
                K  +  S T  + +  +       +++    D   + + A+N  G    T +  V L
Sbjct: 23503 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV-L 23561

Query: 1960  EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
             ++    P PP  P+ I  V +     +W  P  DGG+ ++ Y +  R+ ++ +W  V   
Sbjct: 23562 DR----PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DA 23616

Query: 2020  DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
             +V TL   +  L E + Y  RI A N+ G+ EPLES+
Sbjct: 23617 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE 23653



 Score =  205 bits (500), Expect = 1e-50
 Identities = 242/1076 (22%), Positives = 420/1076 (39%), Gaps = 69/1076 (6%)

Query: 633  PPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP--DENISVAIESDMH 689
            PP F KK +A + V  G    LEC++   PE  + W F+ E  +P  D+     I+S   
Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW-FRNEHELPASDKYRMTFIDS--- 6404

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIEPLKSMIVR 747
               +V+++ N+     G +   A N  G  S    +++K        P ++E LK+    
Sbjct: 6405 --VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNA--- 6459

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
                V L  ++ G P   + W K+ + +   K     S     SI IL      D G Y 
Sbjct: 6460 ---EVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVD-TSDIGEYH 6515

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             KA+N  G    + V TV+       EPP F+++   +TV      +L A +       +
Sbjct: 6516 CKAQNEVG--SDTCVCTVKLK-----EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFV 6568

Query: 865  TWYRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             W +  E +I  SE I   F  EN+  +        ++G Y C   N  G   + A + +
Sbjct: 6569 QWLKEKEEVIRESENIRITFV-ENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV 6627

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRX 981
             +E    V+       T  G+T  LEC+ + T  +S +WY + K ++     +     + 
Sbjct: 6628 -LEPAVIVEKAGPMTVTV-GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI 6685

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAI 1035
                       D G     V++   ++S   VV    +   P F R+L++         I
Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCI 6745

Query: 1036 LEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD- 1093
            LE ++  S    V W  +   I     KY      ++  L + +    D G Y+C+  + 
Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGA-KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 6804

Query: 1094 ---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149
               + C A +TV E PP  +   +  +V  G   TF   +       V WF+   E+   
Sbjct: 6805 AGSDECRAVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 6863

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEF 1205
            +   +  +    +L++++ D+  +GEY+C V N+     CT  L V+EP+  F  RL + 
Sbjct: 6864 DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA-FLKRLSDH 6922

Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
             + P  +    +       + VTW K    I  +EK  +++  K   L I   T+ D  +
Sbjct: 6923 SVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQ 6982

Query: 1266 YTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            Y+C + +   +      V  +E PP  V          G  V+L       P+    W  
Sbjct: 6983 YSCEIENEAGRDVCGALVSTLE-PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYK 7041

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
                ++     +    +  A+L   KV   D+G Y  + EN+ G A  +    I ++  P
Sbjct: 7042 GDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP 7101

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE---IDTTEWISVKNITKTQTSI 1440
            P     L+    ++ +          S  I  V  Y++   +   E +    +    T +
Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDDENLQTSFVDNVAT-L 7159

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            + L+T+ S+  +        +  AS +       +E K +SP  +    +I     E  +
Sbjct: 7160 KILQTDLSHSGQYSCSASNPLGTASSSARL--TAREPK-KSPFFDIKPVSIDVIAGESAD 7216

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
              C   G    ++TW +D K+++           N                Y C A ND 
Sbjct: 7217 FECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 7276

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G+   S  + +++ P   +   +  +  K G+   +   I G P  +V W++N ++L   
Sbjct: 7277 GKDMCSAQLSVKEPPKF-VKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 7335

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             +YN++     +++ I E     S  Y  EA N  G +S    L V   P   + P
Sbjct: 7336 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKP 7391



 Score =  205 bits (500), Expect = 1e-50
 Identities = 228/1047 (21%), Positives = 410/1047 (39%), Gaps = 71/1047 (6%)

Query: 1103  VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
             +E+ P +        V    +   ++    +  A V W KDG  ++ +  + ++      
Sbjct: 26318 IEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 26377

Query: 1162  KLKIYDCDLDDAGEYSCEVGNSKCT-----AILTVEEPSINFTLRLPEFILVPANTDAYL 1216
              L I +   +D G Y   V NS  +      I+ ++ P     +R+ E +   + T ++ 
Sbjct: 26378 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDE-VSCDSITISWN 26436

Query: 1217  TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCV--LLD 1272
               E  D    ++ Y  +     +  + ++S    RT I  +R  T  +     C      
Sbjct: 26437 PPEY-DGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYG 26495

Query: 1273  AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
               S ++    V E+P          ++   +  T+LV +Q         ++   +  + K
Sbjct: 26496 KSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL--EYK 26553

Query: 1333  HTKPSIDSKSASLTIK----KVENTDAGI---YKLRLENNCGHADVEMN---VTILDKPS 1382
                  + SK+  + I     KV   D G+   Y++  EN  G      +   V   D   
Sbjct: 26554 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 26613

Query: 1383  PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSI 1440
             PPG+P +  I   S+++ W +P   G + I  Y+VE +E+    W+     NI +T   +
Sbjct: 26614 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 26673

Query: 1441  QNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTEPN 1496
               L  +  Y FR +A N  D +S+ SE+T    +I +  ++ P V   +K    I  +  
Sbjct: 26674 TELTEDQRYEFRVFARNAADSVSEPSESTG--PIIVKDDVEPPRVMMDVKFRDVIVVKAG 26731

Query: 1497  EDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
             E +++     G P P ++W +DG    ++ +T   + +N                Y    
Sbjct: 26732 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 26791

Query: 1553  FNDHGEVETSCVVGIQQKPVITISNEDIK--QKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
              N  G    +    +  KP       +I      K    W       G    ++ +Y   
Sbjct: 26792 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGA---DIDYYIVE 26848

Query: 1611  NKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSV--EVTLKVYDKPS 1667
              +  +   + I   E + +  ++ +L + +   + +   N  G       V +K  D  +
Sbjct: 26849 KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFT 26908

Query: 1668  KPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
              P  P  +    +++ES+T+ W  P  DGG E++ Y IE+ E ++ RW++V    + V  
Sbjct: 26909 VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNK--KPVYD 26966

Query: 1726  YCIQK--LNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNE 1782
               ++   L E CEY +RV A+N  G S   E+ P++  +  + +PS              
Sbjct: 26967 LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS-GKT 27025

Query: 1783  SVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIY 1840
             ++ I W     +GG+PI  Y VE K+ +   WK            I  L+    Y FR+ 
Sbjct: 27026 TITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVK 27085

Query: 1841  ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
             + N++G S P  S D     +    P    +  + ++        +T      G P+ N 
Sbjct: 27086 SVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN- 27144

Query: 1901  IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             ++  K          V    S     IEN    D   + ++ +N +  +  T      + 
Sbjct: 27145 VLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT-----LVV 27199

Query: 1961  KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
             K    P PPT  + ++ V     + SW  PE DGGAP+  Y+I  R+ +K  W+ V   +
Sbjct: 27200 KVLDTPGPPTN-ITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTN-N 27257

Query: 2021  VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVX 2080
              N L + + +L E   Y  R+   NE G+  P E+ E  K+         E+P    ++ 
Sbjct: 27258 CNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI--------TEKPSPPEKLG 27309

Query: 2081  XXXXXXXXXXXXWLR-EHNMDADIRSY 2106
                         WL+ EH+  + I  Y
Sbjct: 27310 VTSISKDSVSLTWLKPEHDGGSRIVHY 27336



 Score =  202 bits (494), Expect = 6e-50
 Identities = 174/670 (25%), Positives = 270/670 (40%), Gaps = 36/670 (5%)

Query: 1315  PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
             P P   W      + K +    ++ +KS  L IK     D G Y +   N+CG       
Sbjct: 16059 PVPTKVWTKEEGELDKDRVVIDNVGTKS-ELIIKDALRKDHGRYVITATNSCGSKFAAAR 16117

Query: 1375  VTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
             V + D P P    KP +       +N  W +PE+ G S I  +++E ++     W     
Sbjct: 16118 VEVFDVPGPVLDLKPVVTNRKMCLLN--WSDPEDDGGSEITGFIIERKDAKMHTWRQPIE 16175

Query: 1433  ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
               +++  I  L     Y+FR  A N+       E      V       SP      +   
Sbjct: 16176 TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTK 16235

Query: 1493  TEPNEDIELTCIFGGVP-QPKVTWYR--DGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
             +    D +     GG P Q  +   R  D    +                        ++
Sbjct: 16236 STITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFR 16295

Query: 1550  CIAFNDHGEVETSCVVGI-----QQKPVITI--SNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
               A N+ GE E S  + +     +  P I +  S      K K G+   + A + G+P P
Sbjct: 16296 VKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMP 16355

Query: 1603  EVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGTSSV 1656
             ++ W KN   +E   +    TKE+ S       + I +  R     YT+ ASN  G+   
Sbjct: 16356 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 16415

Query: 1657  EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WI 1714
              V ++VYD+PS P   + + +I  ES  + W  PLD+GG E+T Y I+K +    +  W 
Sbjct: 16416 NVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWE 16474

Query: 1715  KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
             +V +   + + Y I KL  N +Y FRV A N  G S+  +S+ +VI+    +P       
Sbjct: 16475 EVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPK 16533

Query: 1775  XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT 1833
                     S+ ++W P   NGGSPI  Y +E ++EG   W            ++ +  N 
Sbjct: 16534 VLARTKG-SMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 16592

Query: 1834  T-------YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
                     YQFR  A N  G   P    D    G  + PP  P    V + T  S++L W
Sbjct: 16593 PRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGW 16652

Query: 1887  TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAEN 1944
               P  +GGSPI  YI+E +      W ++      +   E  + N+KE  +  FR+ A N
Sbjct: 16653 KPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVN 16712

Query: 1945  TVGVSLPTES 1954
               G S P+++
Sbjct: 16713 EAGESEPSDT 16722



 Score =  202 bits (494), Expect = 6e-50
 Identities = 217/903 (24%), Positives = 372/903 (41%), Gaps = 67/903 (7%)

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRT 1252
             PS+   ++L E ++V A T       I    +    W    S I+  E +T+ +D     
Sbjct: 18435 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 18494

Query: 1253  LIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
             L I+ C   D  EY   + +A    T  + + V++ P           I   +   + + 
Sbjct: 18495 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG---PINILDVTPEHMTIS 18551

Query: 1311  YQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAG---IYKLRLENN 1365
             +Q         ++N  I++K    K +  + S  +S T  K+ +   G   ++++R EN 
Sbjct: 18552 WQPPKDDGGSPVINY-IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 18610

Query: 1366  CGHAD-VEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
              G    ++   T+       PSPPGKP + +I  ++  + W  P++ G S I  Y +E +
Sbjct: 18611 IGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR 18670

Query: 1421  EIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             E+ T +W+ V    I   +  +  L   ++Y FR +A N   +S  S +++  K  +  K
Sbjct: 18671 EV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 18729

Query: 1479  IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
                P +   LK+ + E   D+  T        P + +  + +K  TA+    N+      
Sbjct: 18730 PPGPPINPKLKDKSRE-TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 18788

Query: 1539  XXXXX------XXXXYKCIAFNDHGE------VETSCVVGIQQKPVIT--ISNEDIKQKH 1584
                            ++  A N  GE       E+     I   P +   ++  D+    
Sbjct: 18789 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV- 18847

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             +VG    + A ++G P P++ W K G  L  +K  ++        ++IKE  R+   KY 
Sbjct: 18848 RVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 18907

Query: 1645  IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             I A N++G +     + V D+P  P   + +  +++E+ TI W+ PLD+GG E+T + +E
Sbjct: 18908 ISAKNSSGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVE 18966

Query: 1705  KHEPDNNRWIKVADVDRDVETYCIQ-KLNENCEYMFRVIAQNPVGFSEALESE-PIVIKT 1762
               +P+   W  VA    DV    I+  L  N EY FRV A+N VG    +E++ PI+   
Sbjct: 18967 YRKPNQKGWSIVAS---DVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAIN 19023

Query: 1763  ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821
              +D P                VY+ W   + +GGSP + Y VE + +G   W+       
Sbjct: 19024 PIDRPGEPENLHIADK-GKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSI 19082

Query: 1822  XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                   + +   N  Y+FR+  +NE G S  +   +++ + + L  P      V+    S
Sbjct: 19083 KETHYMVDRCVENQIYEFRVQTKNEGGES-DWVKTEEVVVKEDLQKP------VLDLKLS 19135

Query: 1880  RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-------VTVGGSVHEHCIENIKE 1932
               +T+K  +              E    K K  T +       +       +  +   K 
Sbjct: 19136 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 19195

Query: 1933  KDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992
              D   + ++A NT G  +   + +V L+K       P   L+I  V S+     W  PE 
Sbjct: 19196 SDGGKYVVTATNTAGSFVAYATVNV-LDKPG-----PVRNLKIVDVSSDRCTVCWDPPED 19249

Query: 1993  DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             DGG  +  Y I  +  TK M        V T    +  L E + Y+ R+ A N+IG   P
Sbjct: 19250 DGGCEIQNY-ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPP 19308

Query: 2053  LES 2055
              ES
Sbjct: 19309 TES 19311



 Score =  202 bits (493), Expect = 8e-50
 Identities = 182/753 (24%), Positives = 322/753 (42%), Gaps = 44/753 (5%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V E  +   EC +   P+    WL   +EI  D+   +  +   H    V+K    +   
Sbjct: 12778 VFEKDEAKFECEVSREPKT-FRWLKGTQEITGDDRFELIKDGTKHSM--VIKSAAFE--D 12832

Query: 705   EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             E  Y   A ++     L I+  I+       + + PLK +  ++ ES + + ++  +   
Sbjct: 12833 EAKYMFEAEDKHTSGKL-IIEGIRL------KFLTPLKDVTAKEKESAVFTVEL-SHDNI 12884

Query: 765   TITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
              + W KN++ +   +++  + +G THSIT  K   + D     ++A        + A +T
Sbjct: 12885 RVKWFKNDQRLHTTRSVSMQDEGKTHSITF-KDLSIDDTSQIRVEAMGMS----SEAKLT 12939

Query: 822   VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
             V E        P F  + Q+ T  EK  + L   +++   P + W+++ + I PS+    
Sbjct: 12940 VLEGD------PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVI 12992

Query: 882   NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
               DG+   L++     + D G Y C      G      ++ I+  ++  V+ L  S E  
Sbjct: 12993 KADGKKRMLILKKA-LKSDIGQYTC----DCGTDKTSGKLDIEDREIKLVRPLH-SVEVM 13046

Query: 942   EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
             E +T   E + S   +   W    + +      EI +EG+              G +   
Sbjct: 13047 ETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ 13106

Query: 1001  VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
               + ++S  L VK  +   +R L+D  V   + A  + E++ E   V W   G+ ++P  
Sbjct: 13107 AANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPS- 13165

Query: 1061  NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
             +K      G +  L +R+  + D GE     +D    A + V E P E    L++Q V +
Sbjct: 13166 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 13225

Query: 1121  GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
             G  A  E E+++ +A V+WFK+G+EI  S   ++  DG+ +KL I+DC  +D   Y+C+ 
Sbjct: 13226 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285

Query: 1181  GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
              + K +  L V  P + F   L + + V     A    E+  E   V W+K  + I+  +
Sbjct: 13286 KDFKTSCNLNVVPPHVEFLRPLTD-LQVREKEMARFECELSRENAKVKWFKDGAEIKKGK 13344

Query: 1241  KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFPPKIVDYEREYR 1298
             K+ +IS    R L+I KC  DD+ EY+C +  A+++  L V  E   F   + + E    
Sbjct: 13345 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSE- 13403

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
                 +D   LV   + P     W    + I +    +   + +   L I+     DAG Y
Sbjct: 13404 ----TDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNY 13459

Query: 1359  KLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
               RL ++     V+++    +  S P    ILE
Sbjct: 13460 NCRLPSSRTDGKVKVHELAAEFISKPQNLEILE 13492



 Score =  202 bits (493), Expect = 8e-50
 Identities = 187/693 (26%), Positives = 290/693 (41%), Gaps = 34/693 (4%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
             P  P  P +  +   S+ + W+ P + G S I+ YV+E ++ +   W       I + + 
Sbjct: 23664 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 23723

Query: 1439  SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
              +  L  N  Y FR  A N   +S+ S  + Y K         P     + +IT      
Sbjct: 23724 RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFL 23783

Query: 1499  IELTCIF-GGVP-QPKVTWYRD---GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
                  I+ GG   Q  +    D   G+       T  N+               ++  A 
Sbjct: 23784 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 23843

Query: 1554  NDHGEVETSCVVG---IQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIW 1606
             N  G  E + V G   +++K   P I +  E  K  + + G    +   I+G P PEV W
Sbjct: 23844 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 23903

Query: 1607  YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
              K   ++ +    ++T+   TS++ +  + R  S KYT+   N++GT S  VT++V D P
Sbjct: 23904 GKVDGEIRDAAIIDVTSSF-TSLV-LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23961

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
             S P   + + EI+++SV+I W+PPL DGG ++  Y +EK E     +  V   +    ++
Sbjct: 23962 SPPVN-LKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVV-TNCHKNSW 24019

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              I +L E C Y FRV A+N  G    A  ++PI +      P           +   SV 
Sbjct: 24020 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPG----KITVDDVTRNSVS 24075

Query: 1786  ITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
             ++W   E +GGS II Y VE++ +  +KW          A I  L+    Y FR+ A NE
Sbjct: 24076 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNE 24135

Query: 1845  IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
              G S P +    I + K L      +    S S      LK   P S    P   +  + 
Sbjct: 24136 KGRSDPRSLAVPI-VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG 24194

Query: 1905  KTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
               +  K  T+I VT    +    I+   + D   + I+  N VG       + V L+K  
Sbjct: 24195 LPL--KQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-QKTASIEIVTLDK-- 24249

Query: 1964  TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
               P PP  P++   V +  +  SW  P + GG  +  Y +  RD T T+W +V    V  
Sbjct: 24250 --PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW-DVVSATVAR 24306

Query: 2024  LKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
                 +  L     Y  RI+A N  G S  LESD
Sbjct: 24307 TTLKVTKLKTGTEYQFRIFAENRYGQSFALESD 24339



 Score =  200 bits (488), Expect = 3e-49
 Identities = 172/697 (24%), Positives = 288/697 (41%), Gaps = 38/697 (5%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK---TQ 1437
             P PP  P++ +    S ++ W +P   G   I  YVVE+Q++    WI     T    TQ
Sbjct: 21600 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 21659

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
               + +L+T   Y FR  A+N+  + + +   +   V +E         +  + +      
Sbjct: 21660 FVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGL 21719

Query: 1498  DIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDH 1556
              I +     G P P+VTW +D   LK  +A  EN                  K +   ++
Sbjct: 21720 SIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTLLIIPECNRYDTGKFVMTIEN 21778

Query: 1557  GEVETSCVVGIQ----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
                + S  V ++      PV+ +   DI  K  V   W +  +  G     +  Y    +
Sbjct: 21779 PAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPLIDGG---SRITNYIVEKR 21834

Query: 1613  LENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVT--LKVYDKPSK 1668
                 K Y+  TTK      ++  L       + + A N  G     E T  +K  + PS 
Sbjct: 21835 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP 21894

Query: 1669  PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
             P+   IM +I++ +V++ W  P  DGG ++T Y IE     +++W  +  V + +E   +
Sbjct: 21895 PDSLNIM-DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-KGLECV-V 21951

Query: 1729  QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI-----DNES 1783
             + L E  EY F+V+A N  G S   ES P+++K    +P           +     DN  
Sbjct: 21952 RNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIK 22011

Query: 1784  VYITWFPSEKNGGSPIIDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
             V I      K    P + +K   +I ++ ++             I +   + +  + + A
Sbjct: 22012 VEIPVLGRPK----PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTA 22067

Query: 1842  RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             RN +G      +   I +     PP+ P  F   E +S  VT  W  PE++GG PI+NY+
Sbjct: 22068 RNIVGEVGDVIT---IQVHDIPGPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYV 22122

Query: 1902  IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             +E +     +W ++ T       +    +    E  FR+ A+N  GV     S  +    
Sbjct: 22123 VEMRQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANY 22181

Query: 1962  HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                VP PP  P ++  V  + +  SW  P  DGG+P+LGY++  ++    +W  V K  V
Sbjct: 22182 PFKVPGPPGTP-QVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV 22240

Query: 2022  NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                 F    L++   Y  R+ A N  G S+P +  EP
Sbjct: 22241 PGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEP 22277



 Score =  199 bits (485), Expect = 8e-49
 Identities = 194/869 (22%), Positives = 358/869 (41%), Gaps = 53/869 (6%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284
             VTW   +  +   ++ T+ +     +++I+ C    Q  Y+ +  +     K  + V+V+
Sbjct: 17483 VTWNMNERTLP--QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 17540

Query: 1285  EFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             + P P    +           +T          P   +++  +   +   T  +      
Sbjct: 17541 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 17600

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
             + T++ +    A  +++  EN+ G    VE +  ++ +     P  P    + E+  +++
Sbjct: 17601 NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTV 17660

Query: 1398  NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
              + W+ P+  G S II YV+E + I T ++  V N  +   + +++ LK   +Y +R  A
Sbjct: 17661 TLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSA 17720

Query: 1456  VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVT 1514
             VN V     S  T+   +  + ++  PT+    ++ +T    E   LT  + G P+PKV+
Sbjct: 17721 VNIVGQGKPSFCTK--PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVS 17778

Query: 1515  WYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
             W++D   +    +T   T                   Y  +  N  G  +  C V +  +
Sbjct: 17779 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 17838

Query: 1571  ---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
                PV  +S +++ + + V   W       G      I  K   ++  D    +T+    
Sbjct: 17839 PGPPVGPVSFDEVTKDYMV-ISWKPPLDDGGSKITNYIIEK--KEVGKDVWMPVTSASAK 17895

Query: 1628  SVIRIKELKRSHSSKYTIEASNTAGTSS--VEVTLKVYDK---PSKPEGPVIMREISRES 1682
             +  ++ +L       + I A N  G S   V  ++K  D+   P  P+ P++  E++++S
Sbjct: 17896 TTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV-TEVTKDS 17954

Query: 1683  VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRV 1741
               + W  P  DGG  +T Y +EK E  + RW +V  D       + +  L E C+Y FRV
Sbjct: 17955 ALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRV 18013

Query: 1742  IAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
              A+N +G  + +  S+P+  K  +  PS            N SV +TW P   +GGS I+
Sbjct: 18014 SAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCN-SVDLTWQPPRHDGGSKIL 18072

Query: 1801  DYKVEIKQEG-KKWKXXXXX----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
              Y VE ++ G ++W+              ++  L    TY+FR+ A N  G S P    +
Sbjct: 18073 GYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPE 18132

Query: 1856  KITIGKTLTPPS--QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
              + +   L PP      N    +      TL+ +        P   +  E +    K+  
Sbjct: 18133 PVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI 18192

Query: 1914  KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973
              +  VG  +    I N   +D  I+ ++ EN  G S     + + L+K    P PP   L
Sbjct: 18193 DVTPVGSKLE---IRNAAHEDGGIYSLTVENPAG-SKTVSVKVLVLDK----PGPP-RDL 18243

Query: 1974  EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033
             E+  +  +    +W  P  DGG+ +  Y +  RDV    W  +         F  + L+E
Sbjct: 18244 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNE 18302

Query: 2034  NHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
              + Y+ R+ A N+ G    +E+ +P K +
Sbjct: 18303 GNQYLFRVAAENQYGRGPFVETPKPIKAL 18331



 Score =  198 bits (483), Expect = 1e-48
 Identities = 131/433 (30%), Positives = 196/433 (45%), Gaps = 19/433 (4%)

Query: 1569  QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN--GNKLENDKEYNITTKEK 1626
             QKPV+ +    +    K GD   + A + G P PEV W K+     L       I T+  
Sbjct: 19126 QKPVLDLKLSGVLTV-KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 19184

Query: 1627  TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             +S   + + KRS   KY + A+NTAG+     T+ V DKP       I+ ++S +  T+ 
Sbjct: 19185 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVC 19243

Query: 1687  WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
             W PP DDGG E+  Y +EK E     W   +       T  + +L E  EY+FRV A+N 
Sbjct: 19244 WDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRLIEGNEYIFRVRAENK 19302

Query: 1747  VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
             +G     ES+P++ KT  D P           +  E + + W P E +GG  I  Y +E 
Sbjct: 19303 IGTGPPTESKPVIAKTKYDKPGRPDPPEVTK-VSKEEMTVVWNPPEYDGGKSITGYFLEK 19361

Query: 1807  KQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
             K++   +W           R  +Q L  +  YQFR+ A NEIG   P      +     +
Sbjct: 19362 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 19421

Query: 1864  TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-----TVKGKSWTKIVTV 1918
              PP  P NF V ++T  S+TL W +P  +GG+PI  Y++E +         + W +    
Sbjct: 19422 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 19481

Query: 1919  GGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
                V  E  + ++ E  E  FR+ A+N VG+  P E +     K   +  PP   L+  M
Sbjct: 19482 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKE--ILEPPEIDLDASM 19539

Query: 1978  VGSNIVMTSWGTP 1990
                 +V+   G P
Sbjct: 19540 --RKLVIVRAGCP 19550



 Score =  198 bits (483), Expect = 1e-48
 Identities = 168/659 (25%), Positives = 292/659 (44%), Gaps = 41/659 (6%)

Query: 1137  VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
             ++W++ G E+  S   +++ DG+   L +   + +D G Y+C    EVG  + ++ L ++
Sbjct: 31491 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 31550

Query: 1193  E-PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250
               P  +    L E       +   L V      +  +TW+  + +++++E  T+ +    
Sbjct: 31551 ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHY 31610

Query: 1251  RTLIIRKCTEDDQC-EYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               L+++         +Y   L +   T    L VE+ + P K         + + S V  
Sbjct: 31611 THLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAV-- 31668

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENT--DAGIY-KLR 1361
              + ++        WI N  +++KC+  + +   + S + S+T  ++ N   +AG Y ++ 
Sbjct: 31669 -ISWKPPADDGGSWITNY-VVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVS 31726

Query: 1362  LENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
              +N  G +D +E++  ++     +KP  PGKP I  +   S  + W  P + G + I  Y
Sbjct: 31727 AQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNY 31786

Query: 1416  VVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
              +E +E    +WISV  + I +T  S++NL     Y FR    N    S+ SE +E    
Sbjct: 31787 YLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITP 31846

Query: 1474  IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
               +  IQ+P  ++ L+N+      +  L C   G P+P V WYR GK++      Y  + 
Sbjct: 31847 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQE 31906

Query: 1534  XXXX------XXXXXXXXXXYKCIAFNDHGEVE--TSCVVGIQQKPVITISNEDIKQKHK 1585
                                 Y+  A N  G V    S  V +  K  +  + E +   H 
Sbjct: 31907 FKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHA 31966

Query: 1586  V-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKY 1643
             + G+   +     G P P + W K  + ++N+  Y  I T+  TS++    ++R  +  Y
Sbjct: 31967 LRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 32026

Query: 1644  TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
              + A N  G     V L V D P  P G V + ++SR+SV + W  P  DGG ++T Y +
Sbjct: 32027 VVCAKNRFGIDQKTVELDVADVPDPPRG-VKVSDVSRDSVNLTWTEPASDGGSKITNYIV 32085

Query: 1704  EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761
             EK      RW++V    R+   Y +  L     Y FRVIA+N  G S+  E SEP + K
Sbjct: 32086 EKCATTAERWLRVGQA-RETR-YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITK 32142



 Score =  196 bits (477), Expect = 7e-48
 Identities = 175/699 (25%), Positives = 298/699 (42%), Gaps = 44/699 (6%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437
             P PP  P + +   SS+++ W +P   G + +  YVVE +E    EW +      +   Q
Sbjct: 25930 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 25989

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
              ++  LK N+ Y FR  A+N   + + +  T    V+ + +I+ P +E      K +   
Sbjct: 25990 FTVTKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLR 26047

Query: 1495  PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCI 1551
              +  + L     G P+P+V W +  + + T +A  E   +                Y   
Sbjct: 26048 ASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLT 26106

Query: 1552  AFNDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
               N+ G       V +   P   + ++  ++K K  V   W    +I+G    ++  Y  
Sbjct: 26107 LENNSGSKTAFVNVRVLDSPSAPVNLTIREVK-KDSVTLSW-EPPLIDG--GAKITNYIV 26162

Query: 1610  GNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV-YDKP 1666
               +    K Y  IT     +  RI+ L+   S  + + ASN  G     E T  V   +P
Sbjct: 26163 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 26222

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
               P G V + +++R + TI+W+ P  DGG ++T Y +E     + +W     V + +E  
Sbjct: 26223 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQV-KTLEA- 26280

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              I  L    EY+FRV A N  G S+  +   P++ +     PS             E + 
Sbjct: 26281 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340

Query: 1786  ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNE 1844
             I   P +   G P     V  +++G+  K         ++ +  LSI         ++ +
Sbjct: 26341 ID-VPFK---GRP--QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEA------SKED 26388

Query: 1845  IGTSLPYTSDD--KITIGKT---LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             +GT     S+    IT+  T   L  P  P    + E +  S+T+ W  PE +GG  I+N
Sbjct: 26389 VGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN 26448

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
             YI+E K     +W  IV+   +     I  +    E  FR+ AEN  G S  +ES +V  
Sbjct: 26449 YIVEKKETTSTTW-HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 26507

Query: 1960  EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
             E   + P PP  P  +    S +++T W  P  DGG+ ++GY++  ++ +  +W +  K+
Sbjct: 26508 EYPFSPPGPPGTPKVVHATKSTMLVT-WQVPVNDGGSRVIGYHLEYKERSSILWSKANKI 26566

Query: 2020  DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              +   +  +  L E   Y  R+YA N  G+ +  +S EP
Sbjct: 26567 LIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEP 26605



 Score =  195 bits (475), Expect = 1e-47
 Identities = 186/711 (26%), Positives = 309/711 (43%), Gaps = 65/711 (9%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437
             P+PP  P + +   SS+++ W +P   G S II Y+VE +  D+  W+     +N+ KT+
Sbjct: 20516 PAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 20575

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPN 1496
               +  L  ++ Y+FR YAVN++  SD S+  + +            ++  L K +     
Sbjct: 20576 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 20635

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCI 1551
               + L     G P PK+TW +    L+       K+T +                 Y   
Sbjct: 20636 VTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKST-DFDTFLRCENVNKYDAGKYILT 20694

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT---AVIEGIPPPEVIWYK 1608
               N  G+ E + VV +   P   + N  +K+  K  D   VT    +I+G  P  +I Y 
Sbjct: 20695 LENSCGKKEYTIVVKVLDTPGPPV-NVTVKEISK--DSAYVTWEPPIIDGGSP--IINYV 20749

Query: 1609  NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                +    K ++  T E  KTS  R+  L+   S  + + A N  G      T     K 
Sbjct: 20750 VQKRDAERKSWSTVTTECSKTS-FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAV-KA 20807

Query: 1667  SKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             S+  GPV+   +R +S+ S +I WK P  DGG  +  Y ++    + N+W +V      +
Sbjct: 20808 SQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRVMK-SLSL 20865

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
             + Y  + L E  EY FRV A+N  G  E   SE I +    DV +          +D + 
Sbjct: 20866 Q-YSAKDLTEGKEYTFRVSAENENG--EGTPSE-ITVVARDDVVAPD--------LDLKG 20913

Query: 1784  VYITWFPSEKNGGSPIIDYKVEIKQEGK-----KWKXXXXXXXXXARI--QKLSINTTYQ 1836
             +    + +++N      +++++I  +GK      WK          R+  +  ++NTT  
Sbjct: 20914 LPDLCYLAKENS-----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLI 20968

Query: 1837  FRIYARNEIGT------SLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEP 1889
                  +++ G       ++  T +  I+I K +  P  P   +   E T+ ++TLKW  P
Sbjct: 20969 VYDCQKSDAGKYTITLKNVAGTKEGTISI-KVVGKPGIPTGPIKFDEVTAEAMTLKWAPP 21027

Query: 1890  ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVG 1947
             + +GGS ITNYI+E +      W   VT   +V +    +  + E  E  FR+SAEN  G
Sbjct: 21028 KDDGGSEITNYILEKRDSVNNKW---VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 21084

Query: 1948  VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
             V    +S+ +       VP  P  P  I  V  + V  +W  P+  GG+P+ GY++  ++
Sbjct: 21085 VGEGLKSEPIVARHPFDVPDAPPPP-NIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKE 21143

Query: 2008  VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                 +W    K  +    F +  L+E   Y  R+ A N  G+ +P    EP
Sbjct: 21144 RNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEP 21194



 Score =  194 bits (474), Expect = 2e-47
 Identities = 212/907 (23%), Positives = 361/907 (39%), Gaps = 56/907 (6%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249
             +E P I+  L L + I + A     L V I    T +V W K    I D     + S   
Sbjct: 23864 LEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 23923

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               +L++      D  +YT  L ++  T    + V V++ P   V+ +     K    +T 
Sbjct: 23924 --SLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW 23981

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
                          +IV  +   +  +     +    S  I +++   +  +++  EN  G
Sbjct: 23982 EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 24041

Query: 1368  ---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                 A     + + + P PPGK  + ++  +S+++ W +PE+ G S II Y+VE Q   +
Sbjct: 24042 IGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHS 24101

Query: 1425  TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
              +W     +   Q  I NL     Y FR  AVNE   SD         ++ +  +  P V
Sbjct: 24102 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA--VPIVAKDLVIEPDV 24159

Query: 1485  EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544
             +    + + +  +D+++     G P+P +TW +DG  L   K T                
Sbjct: 24160 KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL---KQTTRINVTDSLDLTTLSI 24216

Query: 1545  XXXYKCIAFNDHGEVETSCVVGIQQK----PVITISNED-IKQKHKVGDEWLVTAVIEGI 1599
                +K    +D G+   +    + QK     ++T+   D  K   K  D    +  +   
Sbjct: 24217 KETHK----DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWN 24272

Query: 1600  PPPEVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGT 1653
             PP      +  N +   ++   T  +  S       +++ +LK     ++ I A N  G 
Sbjct: 24273 PPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQ 24332

Query: 1654  S-SVEVTLKVYDKPSK---PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
             S ++E    V   P K   P G      IS++S+ I+W  P+++GG  +  Y +E+ E +
Sbjct: 24333 SFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 24392

Query: 1710  NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPS 1768
             +  W KV         +  Q L E  EY FRV A+N VG  +A + SE  V +   D P 
Sbjct: 24393 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 24452

Query: 1769  XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-R 1825
                       +    + + W     +GGS I  Y VE +   +G+  K            
Sbjct: 24453 ----TPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFT 24508

Query: 1826  IQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSV 1882
             +  L+ +  Y+FR+ A+N  G  S P  S   IT    +  P  S    F  +   +   
Sbjct: 24509 VSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGE 24568

Query: 1883  TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
             T +          P   ++   K ++  +  +I           +++    D   + + A
Sbjct: 24569 TFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA-LLIVKDAIRIDGGQYILRA 24627

Query: 1943  ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
              N  G    ++S  V + K    P PP  P+++  V S     +W  P  DGG+ +  Y 
Sbjct: 24628 SNVAG----SKSFPVNV-KVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 24682

Query: 2003  IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES-----DE 2057
             +  R+ ++  W  V   +V T    +  L E + Y+ RI A N+ G+ EPLES       
Sbjct: 24683 VEKRETSRLAWTVVAS-EVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741

Query: 2058  PFKVIPG 2064
             PF V+PG
Sbjct: 24742 PF-VLPG 24747



 Score =  192 bits (467), Expect = 1e-46
 Identities = 176/700 (25%), Positives = 303/700 (43%), Gaps = 46/700 (6%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NIT 1434
             +D P PP K  I +   SSI + W +P   G S +  YVVE ++ +  EW +V     + 
Sbjct: 28091 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 28150

Query: 1435  KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNI 1491
              T+  + NLK   +Y FR  AVN     +  E  E   V  +  +++P ++  +    ++
Sbjct: 28151 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE--PVQAKDILEAPEIDLDVALRTSV 28208

Query: 1492  TTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXX---XXXXXXXX 1547
               +  ED+++   F G P P VTW +D K L   A+ + EN                   
Sbjct: 28209 IAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGK 28268

Query: 1548  YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKH-KVGDEWLV--TAVIEGIPPPE 1603
             Y     N  GE ++S V V +   P    + + ++ KH   G   L+    +I+G  P  
Sbjct: 28269 YILTIENGVGEPKSSTVSVKVLDTPA---ACQKLQVKHVSRGTVTLLWDPPLIDGGSP-- 28323

Query: 1604  VIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS-VEVT-- 1659
             +I Y    +    + +++ + + +S   ++ +L       + + A N  G     E T  
Sbjct: 28324 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP 28383

Query: 1660  LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
             +K  + P+ P   + M++ ++ SV + W  P  DGG  +T+Y +E+       W   A +
Sbjct: 28384 VKAAEVPA-PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAGI 28441

Query: 1720  DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
              +  E   + +L E     FRV A+N  G S+ +   PI +K  +  P           +
Sbjct: 28442 SKTCEIE-VSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQV 28500

Query: 1780  D---NESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSINTT 1834
                   +V++   P  K    P I +  +    +E +  +           I+       
Sbjct: 28501 TVRIGHNVHLE-LP-YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 28558

Query: 1835  YQFRIYARNEI-GTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESN 1892
              ++ +   N +   ++P T    IT+G    PPS+P+  +   E  + SV L W  PE N
Sbjct: 28559 GKYTVILDNAVCRIAVPIT---VITLG----PPSKPKGPIRFDEIKADSVILSWDVPEDN 28611

Query: 1893  GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             GG  IT Y IE +     +W K+V    +     + N+ +  E  FR+ AEN  GVS P 
Sbjct: 28612 GGGEITCYSIEKRETSQTNW-KMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPL 28670

Query: 1953  ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
              S  +  +    +P PP  P+ I  V S+ +  +W  P +DGG+ + G+++  ++    +
Sbjct: 28671 VSSIIVAKHQFRIPGPPGKPV-IYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL 28729

Query: 2013  WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             W +V    ++  ++    L E   Y  R+YA N  GLS P
Sbjct: 28730 WQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 28769



 Score =  191 bits (466), Expect = 2e-46
 Identities = 205/757 (27%), Positives = 301/757 (39%), Gaps = 73/757 (9%)

Query: 1349  KVENTDAG-IYKLRL--ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
             KV    AG IY+ R+  EN  G    +     V  +D   PP    I +I  +S+++ W 
Sbjct: 27657 KVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 27716

Query: 1403  EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEV- 1459
             +P   G S I  Y+VE +++    W   S  N+T+TQ  I  L  NS Y FR +A N V 
Sbjct: 27717 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 27776

Query: 1460  DISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTEPNEDIELTCIFGGVPQPKVTWY 1516
              IS+ SE       I       P ++ PL+    +       ++L     G P P + WY
Sbjct: 27777 SISNPSEVVGPITCIDS--YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWY 27834

Query: 1517  RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAF---NDHGEVETSCVVGIQQKP- 1571
             +D K+L+T A    EN                  C      N  G    +  V I  KP 
Sbjct: 27835 KDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPG 27894

Query: 1572  -------VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
                      T++ E I    +     G   +   ++E      V+W      LE   E  
Sbjct: 27895 PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE---ECI 27951

Query: 1621  ITTKEKTSVIRIKE--LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
             ITT   T +I+  E   +    +KY I       + SV V    +  P  P  P + + I
Sbjct: 27952 ITT---TKIIKGNEYIFRVRAVNKYGI--GEPLESDSV-VAKNAFVTPGPPGIPEVTK-I 28004

Query: 1679  SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEY 1737
             ++ S+T+ W  P+ DGG +++ Y +EK +  +  W KV  +  RD     +  L EN +Y
Sbjct: 28005 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQK-VTGLTENSDY 28063

Query: 1738  MFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
              +RV A N  G  +   SEP     A D   P               S+ + W     +G
Sbjct: 28064 QYRVCAVNAAG--QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDG 28121

Query: 1796  GSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPY 1851
             GS +  Y VEI+Q E ++W               +  L     Y FR+ A N  G   P 
Sbjct: 28122 GSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 28181

Query: 1852  TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKG 1909
               ++          P Q ++ + +      V L+ T   +  G  +   +I FK      
Sbjct: 28182 EMNE----------PVQAKDILEAPEIDLDVALR-TSVIAKAGEDV-QVLIPFKGRPPPT 28229

Query: 1910  KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP--- 1966
              +W K     GS   + IEN      +       N  G  + T    V   K +TV    
Sbjct: 28230 VTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV 28289

Query: 1967  -SPPTA--PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
                P A   L+++ V    V   W  P  DGG+P++ Y I  RD TK  W  V     +T
Sbjct: 28290 LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSST 28349

Query: 2024  LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
               F + DLSE   +  R+ A NEIG+ EP E+ EP K
Sbjct: 28350 -SFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK 28385



 Score =  190 bits (462), Expect = 5e-46
 Identities = 204/900 (22%), Positives = 371/900 (41%), Gaps = 65/900 (7%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249
             +E P I     L + +++ A+    L V I      +V W K + ++ D  +  + S   
Sbjct: 26029 IEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFT 26088

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
                L+I   T  D   Y   L +     T  + V V++ P   V+      +K+ S VTL
Sbjct: 26089 M--LVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDS-VTL 26144

Query: 1308  LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGI---YKLRL 1362
               +    P  +    + + I++K + T+ +  +   + + T  ++EN   G    +++  
Sbjct: 26145 SWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 26201

Query: 1363  ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
              N  G    A+    V + + P PPG+  ++++  ++  I W++PE+ G S I  YVVE 
Sbjct: 26202 SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEM 26261

Query: 1420  QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
             Q   + +W +   +   + +I  L     Y FR  AVNE   SD  +      + ++ +I
Sbjct: 26262 QTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ-LGVPVIARDIEI 26320

Query: 1480  QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXX 1538
             + P+VE P      +  E +++   F G PQ  V W +DG+ LK T +    +       
Sbjct: 26321 K-PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 26379

Query: 1539  X---XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                         Y+    N  G +     + +  +P             ++ +    +  
Sbjct: 26380 SIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRP-------GPPGPIRIDEVSCDSIT 26432

Query: 1596  IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASN 1649
             I   PP      +  N +   KE   TT    S       I+I  L      ++ + A N
Sbjct: 26433 ISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 26492

Query: 1650  TAGTSSV-EVTLKVYDKPSKPEGPVIMREI---SRESVTIEWKPPLDDGGLELTKYAIEK 1705
               G SS  E +  V + P  P GP    ++   ++ ++ + W+ P++DGG  +  Y +E 
Sbjct: 26493 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 26552

Query: 1706  HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTAL 1764
              E  +  W K   +        +  L+E   Y +RV A+N  G  +  +S EP+  +   
Sbjct: 26553 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 26612

Query: 1765  DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXX 1821
             D P           I  +SV + W     +GG+ I  Y VE ++  +G+  K        
Sbjct: 26613 DPPG----QPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 26668

Query: 1822  XXARIQKLSINTTYQFRIYARNEI-GTSLPYTSDDKITIGKTLTPPSQPRNFVVSE--ST 1878
                 + +L+ +  Y+FR++ARN     S P  S   I +   + PP    +    +    
Sbjct: 26669 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVV 26728

Query: 1879  SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE---KDE 1935
                  LK     +    P+ ++  +   ++ ++ T+I+    S   H +  +K+   +D 
Sbjct: 26729 KAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII----STDNHTLLTVKDCIRRDT 26784

Query: 1936  IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
               + ++ +N  G    T S +V   K    P PP  PLEI  + +     SWG P+ DGG
Sbjct: 26785 GQYVLTLKNVAG----TRSVAVNC-KVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGG 26839

Query: 1996  APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
             A +  Y +  R+ +   W  + + ++      +  L + + Y+ R+   N+ G+ EPLES
Sbjct: 26840 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 26898



 Score =  187 bits (456), Expect = 3e-45
 Identities = 169/699 (24%), Positives = 289/699 (41%), Gaps = 43/699 (6%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436
             KP PP  P +++I  SS+ + W +P   G   I  Y+VE  ++   EW        I KT
Sbjct: 23764 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKT 23823

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493
                ++ L     Y FR  A+N+  + + ++      +I E K+++P ++  L   K I  
Sbjct: 23824 NIEVEKLLEKHEYNFRICAINKAGVGEHADVPG--PIIVEEKLEAPDIDLDLELRKIINI 23881

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCI 1551
                  + L     G P P+V W +   +++ A       +                Y   
Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 23941

Query: 1552  AFNDHGEVETSCVVGI--QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
               N  G       V +     P + +   +I  K  V   W    +  G      I  K 
Sbjct: 23942 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEI-TKDSVSITWEPPLLDGGSKIKNYIVEKR 24000

Query: 1610  GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKP 1666
                        +T   K S  +I +L+   S  + + A N  G      T   +KV + P
Sbjct: 24001 -EATRKSYAAVVTNCHKNS-WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP 24058

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
              +P G + + +++R SV++ W  P  DGG ++ +Y +E     + +W + A V + ++  
Sbjct: 24059 -QPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV-KSLQA- 24115

Query: 1727  CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              I  L +  EY+FRV+A N  G S+    + PIV K  +  P              + + 
Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 24175

Query: 1786  ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA-RIQKLSINTTY-----QFRI 1839
             I    S +    P I +     ++G   K         +  +  LSI  T+     Q+ I
Sbjct: 24176 IEVPISGR--PKPTITW----TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGI 24229

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
                N +G      S + +T+ K   PP  P  F   + ++ S+TL W  P   GG  ITN
Sbjct: 24230 TVANVVGQKT--ASIEIVTLDKP-DPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITN 24284

Query: 1900  YIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             YI++ +      W  +  TV  +  +  +  +K   E  FRI AEN  G S   ES  + 
Sbjct: 24285 YIVQKRDTTTTVWDVVSATVARTTLK--VTKLKTGTEYQFRIFAENRYGQSFALESDPIV 24342

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
              +     P PP  P    +   ++V+  W  P  +GG+P++GY++  ++    +W +V K
Sbjct: 24343 AQYPYKEPGPPGTPFATAISKDSMVI-QWHEPVNNGGSPVIGYHLERKERNSILWTKVNK 24401

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
               ++  +F  ++L E   Y  R+YA N +G+ +  ++ E
Sbjct: 24402 TIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSE 24440



 Score =  186 bits (453), Expect = 6e-45
 Identities = 218/966 (22%), Positives = 386/966 (39%), Gaps = 81/966 (8%)

Query: 1158  GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
             G+K   ++   ++    EYS  +  ++   +  +E P +     L + + + A     L 
Sbjct: 30337 GQKYSFRVAAVNVKGMSEYSESI--AEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 30394

Query: 1218  VEIPDETLDV-TWYKK------KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
             V +      V TW K+      +++I+ TE ++L        LI+ K    D  +YT   
Sbjct: 30395 VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--------LIVDKVNRYDAGKYTIEA 30446

Query: 1271  LD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
              +   K +  + V+V + P          ++K  S  ++ + ++  P  +    VN+ I+
Sbjct: 30447 ENQSGKKSATVLVKVYDTPGPCPSV----KVKEVSRDSVTITWE-IPTIDGGAPVNNYIV 30501

Query: 1329  KKCKHTKPSIDSKSA--SLTIKKVENTDAG-IYKLRL--ENNCG---HADVEMNVTILDK 1380
             +K +    +  + +   S T+ ++     G +Y  R+  EN  G     +    V + + 
Sbjct: 30502 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 30561

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QT 1438
             P  P K  ++++  S++ + W++P   G S +  YV+E  +  T  W+ V  +  T  + 
Sbjct: 30562 PLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH 30621

Query: 1439  SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEP 1495
             ++ +L     Y FR  A NE  +S+  ET      +++ ++  PT++    P K I    
Sbjct: 30622 TVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV-TVQDLRV-LPTIDLSTMPQKTIHVPA 30679

Query: 1496  NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCI 1551
                +EL     G P P  +W+  G KL+ ++     T+                  Y   
Sbjct: 30680 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 30739

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK--N 1609
               N  G    +  V I  KP        I       DE   T++     PPE+      +
Sbjct: 30740 LKNVTGTTSETIKVIILDKPGPPTGPIKI-------DEIDATSITISWEPPELDGGAPLS 30792

Query: 1610  GNKLENDKEYN-----ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             G  +E    +      ++     S  +   L   +   + + A+N  G  S   +  +  
Sbjct: 30793 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 30852

Query: 1665  K-----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
             +     P  PE   I  ++SR+ +T+ W PP DDGG ++T Y +E+ E   +RW++V  V
Sbjct: 30853 RSSIRIPGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKV 30911

Query: 1720  DRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXX 1778
                +  Y    L E  EY  RV A N  G  + +  S+PIV    +  P           
Sbjct: 30912 PVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPI-APPGKPQNPRVTD 30970

Query: 1779  IDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXAR--IQKLSINTTY 1835
                 SV + W   E  GGS +  Y +E+ K +  +W              +  L     Y
Sbjct: 30971 TTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEY 31030

Query: 1836  QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNG 1893
             +FR+ A N  G   P      + + + L  P    +    E     +   ++ T P    
Sbjct: 31031 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGK 31090

Query: 1894  GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
               PI  +  E + +  ++   ++    +  E  I+     D   + +  EN  G     +
Sbjct: 31091 PFPICKWTKEGQDISKRA---MIATSETHTELVIKEADRGDSGTYDLVLENKCG----KK 31143

Query: 1954  SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
             +  +++    + P+ P  PLE   +    V  SW  P  DGGA +LGY +  R+V K  W
Sbjct: 31144 AVYIKVRVIGS-PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAW 31202

Query: 2014  MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
               +    V      ++ L EN  Y  R+ A N+ G+S+PL+S+EP  V P    +  E P
Sbjct: 31203 YTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEP--VTPKTPLNPPEPP 31259

Query: 2074  GEQTEV 2079
                 EV
Sbjct: 31260 SNPPEV 31265



 Score =  186 bits (452), Expect = 8e-45
 Identities = 173/698 (24%), Positives = 291/698 (41%), Gaps = 41/698 (5%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436
             KP PPG P +L+   SSI+I W++P   G S I  Y+VE    +  EW  V     +  T
Sbjct: 22682 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 22741

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493
               +I  L  N  Y+ R YA+N   + + +      K   E ++  P +E      K +T 
Sbjct: 22742 SYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKA--EDRMLPPEIELDADLRKVVTI 22799

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYRD-GKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
                  + L     G P P+V W RD G+ L K +  +  +                Y   
Sbjct: 22800 RACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILT 22859

Query: 1552  AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT---AVIEGIPPPEVIWYK 1608
               N  G       V +   P      +D+K K        +T    +++G    ++  Y 
Sbjct: 22860 VENSSGSKSAFVNVRVLDTPG---PPQDLKVKEVTKTSVTLTWDPPLLDG--GSKIKNYI 22914

Query: 1609  NGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVY 1663
                +    K Y+   T   KTS  ++ +L+   S  + + A N  G    +    ++K  
Sbjct: 22915 VEKRESTRKAYSTVATNCHKTSW-KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 22973

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             ++P  P G + + +++R SV++ W+ P  DGG  +  Y +E     +++W   A V   V
Sbjct: 22974 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK--V 23030

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
                 I  L +  EY FRV AQN  G S+  + S P++ K  +  P+          +  E
Sbjct: 23031 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 23090

Query: 1783  SVYITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
              + +   P        +  +K  V +KQ  +              I+         + + 
Sbjct: 23091 DLKVD-VPFIGRPTPAVTWHKDNVPLKQTTRV-NAESTENNSLLTIKDACREDVGHYVVK 23148

Query: 1841  ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
               N  G ++   +   I + K   PP+ P    + E T+ S+TL W  P+ +GGS I NY
Sbjct: 23149 LTNSAGEAIETLN--VIVLDKP-GPPTGPVK--MDEVTADSITLSWGPPKYDGGSSINNY 23203

Query: 1901  IIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
             I+E +     +W  +  TV  +  + C   +K   E  FRI+AEN  G S    S+    
Sbjct: 23204 IVEKRDTSTTTWQIVSATVARTTIKAC--RLKTGCEYQFRIAAENRYGKSTYLNSEPTVA 23261

Query: 1960  EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
             +    VP PP  P+ + +   + +   W  P  DGG+ ++GY++  ++    +W+++ K 
Sbjct: 23262 QYPFKVPGPPGTPV-VTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 23320

Query: 2020  DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              +   KF    L E   Y  R+ A N +G+ +P +  E
Sbjct: 23321 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE 23358



 Score =  184 bits (448), Expect = 2e-44
 Identities = 168/704 (23%), Positives = 281/704 (39%), Gaps = 46/704 (6%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
             P PP  P + +    + ++ W +P + G S I+ YVVE Q+  T +W  +     I +  
Sbjct: 18731 PGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCA 18790

Query: 1438  TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTE 1494
               +  L   + YRFR  A N V   +  E  E   VI +  +  P VE  +     IT  
Sbjct: 18791 FRVPGLIEGNEYRFRIKAANIVGEGEPRELAE--SVIAKDILHPPEVELDVTCRDVITVR 18848

Query: 1495  PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YEN--RXXXXXXXXXXXXXXXYKC 1550
               + I +     G P+P +TW ++GK L   K     ++  R               Y  
Sbjct: 18849 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 18908

Query: 1551  IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608
              A N  G  + S +V +  +P     N  +    K      W       G    E+  + 
Sbjct: 18909 SAKNSSGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENPLDNGG---SEITNFI 18964

Query: 1609  NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKV 1662
                +  N K ++I   + T  +    L  ++   + + A N  G      T +  + +  
Sbjct: 18965 VEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 19024

Query: 1663  YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
              D+P +PE  + + +  +  V ++W+ P  DGG     Y +E+    ++ W +V      
Sbjct: 19025 IDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK 19083

Query: 1723  VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
                Y + +  EN  Y FRV  +N  G S+ +++E +V+K  L  P           +   
Sbjct: 19084 ETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG 19143

Query: 1783  SVYITWFPSEKNGGSPII----DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838
                I      +    P +    D          + K           + K   +   ++ 
Sbjct: 19144 DT-IRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 19202

Query: 1839  IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
             + A N  G+ + Y + +       L  P   RN  + + +S   T+ W  PE +GG  I 
Sbjct: 19203 VTATNTAGSFVAYATVN------VLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQ 19256

Query: 1899  NYIIEFKTVKGKSWTK----IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
             NYI+E    K   W+     ++T G +V       + E +E IFR+ AEN +G   PTES
Sbjct: 19257 NYILEKCETKRMVWSTYSATVLTPGTTV-----TRLIEGNEYIFRVRAENKIGTGPPTES 19311

Query: 1955  QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
             + V  +     P  P  P E+  V    +   W  PE+DGG  + GY +  ++   T W+
Sbjct: 19312 KPVIAKTKYDKPGRPDPP-EVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWV 19370

Query: 2015  EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              V K  +   +  +++L  +H Y  R+ A NEIG+ EP     P
Sbjct: 19371 PVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRP 19414



 Score =  184 bits (448), Expect = 2e-44
 Identities = 168/697 (24%), Positives = 286/697 (41%), Gaps = 35/697 (5%)

Query: 1380  KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436
             KP PP   +I++   +SI + W +P   G S I+ YVVE  + D  EW  V     +  T
Sbjct: 24846 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 24905

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITT 1493
             +  I  L  +  Y+ R  A+N+V + +A+      K   E K+++P ++   +  K I  
Sbjct: 24906 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVK--PEDKLEAPELDLDSELRKGIVV 24963

Query: 1494  EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKC 1550
                    +   F G P P++TW R+  +  T K   E   N                Y  
Sbjct: 24964 RAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYIL 25022

Query: 1551  IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYK 1608
                N  G       V +   P     N  +K+  K    +LV    +I+G    +V  Y 
Sbjct: 25023 KLENSSGSKSAFVTVKVLDTPGPP-QNLAVKEVRK-DSAFLVWEPPIIDG--GAKVKNYV 25078

Query: 1609  NGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD--K 1665
                +    K Y N+++K   +  +++ L       + + A N  G      T+      +
Sbjct: 25079 IDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE 25138

Query: 1666  PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
             P  P G V + ++S+ S ++ W+ P  DGG  +  Y +E       +W  VA+    V  
Sbjct: 25139 PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCN 25196

Query: 1726  YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
               +  L+   EY FRV A N  G S+  +   P++ K     PS             E +
Sbjct: 25197 AVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 25256

Query: 1785  YITWFPSEKNGGSPIIDYKV-EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
              I   P        I   K  E  ++  +             I++ + +   ++ + A N
Sbjct: 25257 KIE-IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATN 25315

Query: 1844  EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
               GT+   T +  + + +   PP  P  F   E ++  V + W  P   GG  I+NYI+E
Sbjct: 25316 SAGTA---TENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYIVE 25370

Query: 1904  FKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
              +     +W  +  TV  +  +  I  +K   E  FRI AEN  G S P +S++V ++  
Sbjct: 25371 KRDTTTTTWHMVSATVARTTIK--ITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYP 25428

Query: 1963  ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
                P PP  P  +  +  + ++  W  P  DGG  ++GY++  ++    +W+++ K  + 
Sbjct: 25429 FKEPGPPGTPF-VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 25487

Query: 2023  TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
               KF    L E   Y  ++ A N +G+ +P +  E F
Sbjct: 25488 DTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 25524



 Score =  184 bits (447), Expect = 3e-44
 Identities = 107/367 (29%), Positives = 174/367 (47%), Gaps = 6/367 (1%)

Query: 1585  KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
             K G+   + A+++G P P V W+K+G ++E      IT    ++ + +++  R H   YT
Sbjct: 28898 KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYT 28957

Query: 1645  IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
             +EA N +G++  E+ +KV D P K  GP+    I+ E +T+ W  PL+DG   +T Y IE
Sbjct: 28958 VEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE 29017

Query: 1705  KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
             K E     W  + D   + ++Y   KL    EY FRV A N  G    L+S+P+V +   
Sbjct: 29018 KRETSRLAWALIED-KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQY 29076

Query: 1765  DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXX 1822
              VP           I   S+ +TW   E +GGS I  Y +E ++ +  +W K        
Sbjct: 29077 TVPD-APGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPIS 29135

Query: 1823  XAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
               R  +  L+    Y+F + A N  G          I   + + PP  P    V++++  
Sbjct: 29136 ETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKT 29195

Query: 1881  SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
             +V+L+W++P  +GG  I  YIIE        W K+         + + +++  +E  FR+
Sbjct: 29196 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 29255

Query: 1941  SAENTVG 1947
             SA N  G
Sbjct: 29256 SAINGAG 29262



 Score =  183 bits (446), Expect = 4e-44
 Identities = 178/727 (24%), Positives = 290/727 (39%), Gaps = 68/727 (9%)

Query: 1381  PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV----KNITKT 1436
             P PP  P + +   SSI++ W  P   G S I  Y+VE QE  TT+W  V    K IT  
Sbjct: 16632 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 16691

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEP 1495
             +  + NLK    YRFR  AVNE   S+ S+TT         +     ++   ++ +  + 
Sbjct: 16692 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 16751

Query: 1496  NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------------ATYENRXXXXXXXXXXX 1543
                I +  +  G P PK +W  DGK  K  K             T EN            
Sbjct: 16752 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 16811

Query: 1544  XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPP 1602
                 Y   A N  G+   +C V +   P      +D+K      G   L   + +     
Sbjct: 16812 HTGKYSITAKNKAGQKTANCRVKVMDVPG---PPKDLKVSDITRGSCRLSWKMPDDDGGD 16868

Query: 1603  EVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
              +  Y    +  + K +     +  ++   + +L       + + A N  G      T++
Sbjct: 16869 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16928

Query: 1662  ---VYDKPSKPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIE--KHEPDNNR-- 1712
                  D    P+ P+ ++   I++ +V + WKPP +DGG  +T Y +E    +P   +  
Sbjct: 16929 RTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKE 16988

Query: 1713  -WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
              W +    D +   + ++ L E  EY FRV A N  G S+   +         D+P    
Sbjct: 16989 AWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID 17048

Query: 1772  XXXXXXXIDNESVYI------------TWF---PSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
                     +  +V I            TWF   P + +   P++ Y   + +        
Sbjct: 17049 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVL-YDTHVNK-------L 17100

Query: 1817  XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                      I +   + T  + I A N +GT+   + + ++ +     PP  P  F   E
Sbjct: 17101 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTA---SKEMRLNVLGRPGPPVGPIKF---E 17154

Query: 1877  STSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
             S S   +TL W  P+ +GGS ITNY+IE +    K+W  + +       + I  + E  E
Sbjct: 17155 SVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHE 17213

Query: 1936  IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              +FRI A+N  G+  P +S+        +VP  P  P  +  V  N +  +W  PE+DGG
Sbjct: 17214 YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT-VSSVTRNSMTVNWEEPEYDGG 17272

Query: 1996  APLLGYNIAIRDVTKTMWMEVGKVDVNTL----KFNIRDLSENHTYMIRIYARNEIGLSE 2051
             +P+ GY + ++D T   W  V +  +  +     + +  L E   Y  R+YA N  G+  
Sbjct: 17273 SPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGP 17332

Query: 2052  PLESDEP 2058
                  +P
Sbjct: 17333 ASLPSDP 17339



 Score =  182 bits (443), Expect = 1e-43
 Identities = 246/1098 (22%), Positives = 447/1098 (40%), Gaps = 107/1098 (9%)

Query: 631   GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
             GI   F    + Q V EG      C L +  +  + W     ++     + ++ E   H 
Sbjct: 12498 GIRLKFMSPLEDQTVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHK 12556

Query: 691   YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                        + +E T   ++  +     L    ++K  E +P   ++      V + E
Sbjct: 12557 L----------EMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDE 12606

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKA 807
              + L  +V  +    + W K+ + +   P    K+DG    I  +K   +KD+G Y    
Sbjct: 12607 -ITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKADG-LRRILKIKKADLKDKGEYVCDC 12662

Query: 808   ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
                 G  +T A +TVE    +  E PL+     E+ V E    ++       P     W 
Sbjct: 12663 ----GTDKTKANVTVEARLIK-VEKPLY---GVEVFVGETAHFEIELS---EPDVHGQWK 12711

Query: 868   RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
                + ++ S       DG+   L++ N    + +G+    A+N+  KS+  A + +    
Sbjct: 12712 LKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQAANA--KSA--ANLKVKELP 12766

Query: 928   VTFVKHLQ--KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984
             + F+  L   K +E +E K    EC+ S    T +W    +EI+G D  E+I++G     
Sbjct: 12767 LIFITPLSDVKVFEKDEAK---FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSM 12823

Query: 985   XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                     D        +D+ TS  L+++    +F+  L+D   KEK+ A+  VE++ + 
Sbjct: 12824 VIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDN 12883

Query: 1045  ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
               V W ++ + +   ++    +  G    +  ++ S+ D  +        S  A++TV+E
Sbjct: 12884 IRVKWFKNDQRLHTTRS-VSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLE 12942

Query: 1105  LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
               P    +LQ+    + ++   + E++K DA V+WFKDG EI+ S +  +  DGKK+ L 
Sbjct: 12943 GDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLI 13002

Query: 1165  IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
             +      D G+Y+C+ G  K +  L +E+  I     L    ++   T  + T EI ++ 
Sbjct: 13003 LKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFET-EISEDD 13061

Query: 1225  LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
             +   W  K   +  T    +  + K  +L++  C  D          + KS+  L+V+  
Sbjct: 13062 IHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVK-- 13119

Query: 1285  EFPPKIVDYER---EYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
                P+++   R   +  +  G   T    + Y+  P    EW +  K ++      P  +
Sbjct: 13120 ---PRVIGLLRPLKDVTVTAGETATFDCELSYEDIPV---EWYLKGKKLEPSDKVVPRSE 13173

Query: 1340  SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
              K  +LT++ V+  DAG  +L  ++   HA    N+ + + P    KP  LE        
Sbjct: 13174 GKVHTLTLRDVKLEDAGEVQLTAKDFKTHA----NLFVKEPPVEFTKP--LE-------- 13219

Query: 1400  CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
               D+    G + ++   V  +E    +W   KN T+   S +  +  +  R R   +++ 
Sbjct: 13220 --DQTVEEGATAVLECEVS-RENAKVKWF--KNGTEILKS-KKYEIVADGRVRKLVIHDC 13273

Query: 1460  ---DISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
                DI   +   + +K      +  P VE  +PL ++     E     C        KV 
Sbjct: 13274 TPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVK 13332

Query: 1515  WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVI 1573
             W++DG ++K  K  Y+                  KC+  +D  E E SC V   +   ++
Sbjct: 13333 WFKDGAEIKKGK-KYD-----IISKGAVRILVINKCL-LDD--EAEYSCEVRTARTSGML 13383

Query: 1574  TISNED-IKQKHKVGDEWLVTAVIEGI-----PPPEVIWYKNGNKLENDKEYNITTKEKT 1627
             T+  E+ +  K+    E   T  I+ +     P  EVIWYK   ++     Y I T+ + 
Sbjct: 13384 TVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 13443

Query: 1628  SVIRIKELKRSHSSKYT--IEASNTAGTSSV-EVTLKVYDKPS-----KPEGPVIMREIS 1679
              ++ I+      +  Y   + +S T G   V E+  +   KP      + E    +  IS
Sbjct: 13444 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 13503

Query: 1680  RESVTIEWKPPLDDGGLE 1697
             +ES  ++WK   DD  LE
Sbjct: 13504 KESFPVQWK--RDDKTLE 13519



 Score =  181 bits (440), Expect = 2e-43
 Identities = 176/746 (23%), Positives = 300/746 (40%), Gaps = 44/746 (5%)

Query: 795  KKVKDEGVYTLKA---ENSEGIAETSAV-ITVEEPTEENAEP----PLFINRFQEITVKE 846
            +K KDE ++  K    E  + +AE   + I   +P +    P    P    R Q  TV +
Sbjct: 2032 RKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQ 2091

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYK 905
                    RV   P P   WY+N   I  S+ I   +  +N+ ELVI +V +E DS    
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE-DSASIM 2150

Query: 906  CVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHN 963
              A N AG++S  A + +  ++ +TF + LQ     E+      EC+TS   V  KWY +
Sbjct: 2151 VKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD 2210

Query: 964  KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFI 1020
              E+   D   +  + +            D     C++ + E   T+  L+V+  + EF+
Sbjct: 2211 GMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV 2270

Query: 1021 RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
            ++LQD EV E     LE  ++ E  +  W  +   +K    KY    R   + L +++ +
Sbjct: 2271 KELQDIEVPESYSGELECIVSPENIEGKWYHNDVELK-SNGKYTITSRRGRQNLTVKDVT 2329

Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWF 1140
              D+GEYS ++  +  T ++ +   P  I+  L +QKV +G+    E++++       W 
Sbjct: 2330 KEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWM 2389

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200
            KDG E+Q S+ + + ID +   L I D   +DAG YS  +     +    V   S++   
Sbjct: 2390 KDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT 2449

Query: 1201 RLPEFILVPANTDAYL--TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
             L + + V   T A L   V +PD T  V WY     I+  ++   I    K+ L+I + 
Sbjct: 2450 PLKD-VNVIEGTKAVLECKVSVPDVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRT 2507

Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
               D+  Y  ++   ++   L VE +    KI+   R+       +V   V+  +    +
Sbjct: 2508 HASDEGPYKLIVGRVETNCNLSVEKI----KIIRGLRDLTCTETQNVVFEVEL-SHSGID 2562

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
              W    K IK     K     K   LT+  +   D G Y      N     + +    +
Sbjct: 2563 VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAI 2622

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
             KP       + E   +        P++ G                 EW+          
Sbjct: 2623 SKPLT--DQTVAESQEAVFECEVANPDSKG-----------------EWLRDGKHLPLTN 2663

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            +I++       R    A    DI + +      K   + K+++  ++K LKN+T    +D
Sbjct: 2664 NIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQD 2723

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKT 1524
               T          V W ++G  L++
Sbjct: 2724 AVFTVELTHPNVKGVQWIKNGVVLES 2749



 Score =  179 bits (436), Expect = 7e-43
 Identities = 174/747 (23%), Positives = 309/747 (41%), Gaps = 47/747 (6%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            SK    Q V E  + + EC  VA P+    WL  G+ +    NI    ESD H    ++ 
Sbjct: 2623 SKPLTDQTVAESQEAVFECE-VANPDSKGEWLRDGKHLPLTNNIRS--ESDGHKRRLIIA 2679

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
             T +    E TY V       +  +  V KIK          + LK++ V + +  + + 
Sbjct: 2680 ATKLDDIGEYTYKVATSKTSAKLKVEAV-KIK----------KTLKNLTVTETQDAVFTV 2728

Query: 757  QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            ++       + W KN   +++         G  +S+ I K   + DE VY  +     G 
Sbjct: 2729 ELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRI-KNCAIVDESVYGFRL----GR 2783

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
               SA + VE            I + +++T  E  T+     V+ + VP + W+  N  I
Sbjct: 2784 LGASARLHVETVK--------IIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEI 2834

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
             PS+      + +  +L++ N+ S  D+G+Y  V     G+    A++ ++   +T    
Sbjct: 2835 KPSDKHRLVSERKVHKLMLQNI-SPSDAGEYTAVV----GQLECKAKLFVETLHIT---K 2886

Query: 934  LQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
              K+ E  E KT   EC+ SH  V + W  N  EI   +  +I+ +G+            
Sbjct: 2887 TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTE 2946

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            D      +  + + S  L V   +      L+D   +EKD    EV +N E     W ++
Sbjct: 2947 DSAEYTFVCGNDQVSATLTVTPIM--ITSMLKDINAEEKDTITFEVTVNYEGISYKWLKN 3004

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112
            G  IK   +K     +     L IRN    D  +Y+ +    + TA + V     E    
Sbjct: 3005 GVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKH 3063

Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            +++ KV +  +A FE E+++ D  V+W KD  E+Q ++ I++  +    +L I    + D
Sbjct: 3064 IKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
            AG+Y+   G +  TA L VE   +     + + + V     A +  E+ ++ +D  WYK 
Sbjct: 3124 AGKYTVVAGGNVSTAKLFVEGRDVRIR-SIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKD 3182

Query: 1233 KSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
               I  +  E+   + + +   + I +  + D  EYT V    +S+  L V   E PP++
Sbjct: 3183 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE-PPQV 3241

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
            +   +   ++ G            PQP   W    +++      K   D +  +L + + 
Sbjct: 3242 LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEA 3301

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTI 1377
               DA +Y    +N+ G A    ++++
Sbjct: 3302 FPEDAAVYTCEAKNDYGVATTSASLSV 3328



 Score =  178 bits (434), Expect = 1e-42
 Identities = 156/561 (27%), Positives = 249/561 (44%), Gaps = 26/561 (4%)

Query: 804  TLKAENSEGIAETSAVITVEEPT---EENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            T+K    E   E S VI  ++ T   +    P   +    +  V E   ++L  +V+   
Sbjct: 2324 TVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLES 2383

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            V  + W ++ + + PS+ +    D ++  L+I ++  E D+G+Y      + G S+ G  
Sbjct: 2384 VEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE-DAGNYSFTIP-ALGLSTSGRV 2440

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQE 978
                V+ +T +K +       EG   +LEC+ S     S KWY N ++I   D  + I +
Sbjct: 2441 SVYSVDVITPLKDVN----VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2496

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
            G             D G  K IV   ET+  L V++   + IR L+D    E    + EV
Sbjct: 2497 GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI--KIIRGLRDLTCTETQNVVFEV 2554

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
            E++    DV+W    + IKP  +KY  E  G I KL + N    DEG+Y+    +   + 
Sbjct: 2555 ELSHSGIDVLWNFKDKEIKPS-SKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSG 2613

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158
            ++TV      I   L +Q V +  +A FE E+   D+   W +DG  +  +N+I+   DG
Sbjct: 2614 KLTVAG--GAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDG 2671

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
             K++L I    LDD GEY+ +V  SK +A L VE   I  TL+    + V    DA  TV
Sbjct: 2672 HKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLK---NLTVTETQDAVFTV 2728

Query: 1219 EIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            E+    +  V W K   V+E  EK+ +       +L I+ C   D+  Y   L    ++ 
Sbjct: 2729 ELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASA 2788

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            +L VE V    KI+   ++      + V   V       P   +  N +I    KH   S
Sbjct: 2789 RLHVETV----KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIKPSDKHRLVS 2844

Query: 1338 IDSKSASLTIKKVENTDAGIY 1358
             + K   L ++ +  +DAG Y
Sbjct: 2845 -ERKVHKLMLQNISPSDAGEY 2864



 Score =  178 bits (434), Expect = 1e-42
 Identities = 153/697 (21%), Positives = 291/697 (41%), Gaps = 36/697 (5%)

Query: 1382  SPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436
             +PPG P ++++  +S   +++ W +P   G   II Y++E  + D  +W  ++ +   KT
Sbjct: 29179 NPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT 29238

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEP 1495
             + ++ +L+    Y+FR  A+N     D+ E T   K +         ++   K       
Sbjct: 29239 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRA 29298

Query: 1496  NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAF 1553
                I L   + G P P   W +    L       T ++                Y     
Sbjct: 29299 GASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVE 29358

Query: 1554  NDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKN 1609
             N+ G    +  V +   P     I+ +D+ +    G   L+    +++G     +  Y  
Sbjct: 29359 NNSGSKSITFTVKVLDTPGPPGPITFKDVTR----GSATLMWDAPLLDG--GARIHHYVV 29412

Query: 1610  GNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDK 1665
               +  + + + + +++ T  + ++ +L       + + A N  G      +   +   ++
Sbjct: 29413 EKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQ 29472

Query: 1666  PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
             P+ P    ++ + S+ S  + W  P  DGG  +T Y +E  +  ++ W++     +   T
Sbjct: 29473 PAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQ--LT 29529

Query: 1726  YCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + +++L E  EY FRV A+N  G+SE  E+   ++IK     P+          I  ++ 
Sbjct: 29530 FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAG 29589

Query: 1785  YITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
                      +G  +P + +K+E  +  E  +             ++      + ++ +  
Sbjct: 29590 SPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTL 29649

Query: 1842  RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
              N  G      S   + IG+   P + P    VS  ++ S  L W EP+  GG+ ITNYI
Sbjct: 29650 ENTAGVKT--FSVTVVVIGRP-GPVTGP--IEVSSVSAESCVLSWGEPKDGGGTEITNYI 29704

Query: 1902  IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             +E +     +W ++V       +  + ++ +  E  FR+S+EN  GVS P ES  +  E 
Sbjct: 29705 VEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEH 29763

Query: 1962  HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                 PS PT P E+  V +N +   W  P  DGG+ ++GY +  ++    +W++  KV  
Sbjct: 29764 PFVPPSAPTRP-EVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC 29822

Query: 2022  NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                 + +  L E   Y  R YA N  G+S+  E+  P
Sbjct: 29823 LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRP 29859



 Score =  178 bits (433), Expect = 2e-42
 Identities = 212/908 (23%), Positives = 369/908 (40%), Gaps = 68/908 (7%)

Query: 1194  PSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTW------YKKKSVIEDTEKFTLIS 1246
             P       L   ++V A     + V I      +VTW       K ++ IE+TE FTL  
Sbjct: 21701 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL-- 21758

Query: 1247  DVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304
                   LII +C   D  ++   + +   K +  + V V++ P  +++  R   I + S 
Sbjct: 21759 ------LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNL-RPTDITKDS- 21810

Query: 1305  VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAG---IYK 1359
             VTL  D    P  +    + + I++K + T+ S  + +        KV     G    ++
Sbjct: 21811 VTLHWD---LPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFR 21867

Query: 1360  LRLENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             +  EN  G     +    V   + PSPP   NI++I  S++++ W +P++ G S I  YV
Sbjct: 21868 VMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYV 21927

Query: 1417  VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             +E Q   + +W  +  +   +  ++NL     Y F+  AVN    S   E+     ++KE
Sbjct: 21928 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPV--IVKE 21985

Query: 1477  TKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRX 1533
               +      + +  K +  +  ++I++     G P+P VTW +  + LK T +  +E   
Sbjct: 21986 QTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTA 22045

Query: 1534  XXXXXXX---XXXXXXXYKCIAFN---DHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
                              Y   A N   + G+V T  V  I   P   I  +++     V 
Sbjct: 22046 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDF-VT 22104

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
               W       G+P    +      + ++     + T    +  +   L      ++ ++A
Sbjct: 22105 FSWDPPENDGGVPISNYV--VEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKA 22162

Query: 1648  SNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
              N  G     TS+  V    +  P  P  P +   ++++S+TI W  PL DGG  +  Y 
Sbjct: 22163 QNRYGVGPGITSACIVANYPFKVPGPPGTPQV-TAVTKDSMTISWHEPLSDGGSPILGYH 22221

Query: 1703  IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761
             +E+ E +   W  V+        +    L +   Y FRVIA+N  G S+ +  SEP++  
Sbjct: 22222 VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLAL 22281

Query: 1762  TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXX 1819
               +D P           I   +V + W   E  GG  I  Y VE +    G+  K     
Sbjct: 22282 DPIDPPG----KPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 22337

Query: 1820  XXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                    +  L+ +  Y+FR+ A+N  G  S P    D IT    +  P    +    ++
Sbjct: 22338 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 22397

Query: 1878  TSRSVTLKW-TEPESNGGSPIT-NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
                     +  E + +G  P T  +  + K ++G +  +I     S +    ++   +D 
Sbjct: 22398 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-LVNKDSTRRDS 22456

Query: 1936  IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
               + ++A N  G +    +  V L++    P PP  PL +  V S   + SW  P  DGG
Sbjct: 22457 GAYTLTATNPGGFAKHIFNVKV-LDR----PGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 22511

Query: 1996  APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
             A +  Y +  R+ ++  W  V   +V   K  +  L + + Y+ R+ A N+ G+ EPLES
Sbjct: 22512 AKIDHYIVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 22570

Query: 2056  DEPFKVIP 2063
             +    V P
Sbjct: 22571 EPVLAVNP 22578



 Score =  177 bits (432), Expect = 2e-42
 Identities = 242/1060 (22%), Positives = 407/1060 (38%), Gaps = 87/1060 (8%)

Query: 645  VDEGSDILLECRLVAIPE-PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V EG+  +LEC+ V++P+   + W    E+I PD+ +   ++         L I      
Sbjct: 2456 VIEGTKAVLECK-VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHAS 2510

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             EG Y ++    E   +L +  KIK        +I  L+ +   + ++V+   ++  +  
Sbjct: 2511 DEGPYKLIVGRVETNCNLSVE-KIK--------IIRGLRDLTCTETQNVVFEVEL-SHSG 2560

Query: 764  PTITWC---KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
              + W    K  KP      ++ G  + +T+L   K  DEG YT  A   E I  TS  +
Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMK-DDEGKYTFYA--GENI--TSGKL 2615

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            TV          PL      + TV E         V  NP     W R+ + +  +  I 
Sbjct: 2616 TVAGGA---ISKPL-----TDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIR 2666

Query: 881  QNFDGENIELVI--TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
               DG    L+I  T +D +I    YK   S ++ K        + VE V   K L+   
Sbjct: 2667 SESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAK--------LKVEAVKIKKTLKNLT 2717

Query: 939  ETEEGKTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
             TE    V  +E    +    +W  N   +   +   I  +G             D  V 
Sbjct: 2718 VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2777

Query: 998  KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
               +     S  L V ET+ + I+K +D    E      EV ++ +T  V W      IK
Sbjct: 2778 GFRLGRLGASARLHV-ETV-KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIK 2835

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
            P  +K+       + KL ++N S  D GEY+ ++    C A++ V  L   I   ++N +
Sbjct: 2836 PS-DKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETL--HITKTMKNIE 2892

Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
            V +   A+FE E++  +    W K+G EI+ S   ++ + GK  +L I +   +D+ EY+
Sbjct: 2893 VPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2952

Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237
               GN + +A LTV    I  T  L +      +T  +  V +  E +   W K    I+
Sbjct: 2953 FVCGNDQVSATLTVTP--IMITSMLKDINAEEKDTITF-EVTVNYEGISYKWLKNGVEIK 3009

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYER 1295
             T+K  + +     +L IR     D  +YT V   A ST  L VE   +EF   I D  +
Sbjct: 3010 STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI-K 3068

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
                KR      + +    P    +W+ + + ++     K   +     L I     +DA
Sbjct: 3069 VLEKKRAMFECEVSE----PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
            G Y +    N   A + +    +   S   +  ++E   + +    +E +   +      
Sbjct: 3125 GKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGI 3184

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
             + +Q  +  +++  + I +   S         Y F A         + S  T Y     
Sbjct: 3185 EINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-------NRSSVTLYVNAP- 3236

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENR 1532
                + P V + L+ +T +  +      +  G PQPK++WY++ + L T    K  ++ +
Sbjct: 3237 ----EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ 3292

Query: 1533 XXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C A ND+G   TS  + ++   V++   E       +     
Sbjct: 3293 EYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQ 3352

Query: 1592 VTAVIEGIPPP----------EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
             T   EG P            +V WY    K++  + + +T  E T  + I E       
Sbjct: 3353 DTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEG 3412

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
             YT  ASN  G  S    L + + P       I +EI  E
Sbjct: 3413 TYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEME 3451



 Score =  176 bits (429), Expect = 5e-42
 Identities = 155/678 (22%), Positives = 278/678 (41%), Gaps = 27/678 (3%)

Query: 712  AVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
            A+  EG+ ++P     K   +   E P++ E ++S  V QG       +VVG P P   W
Sbjct: 2052 ALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEW 2111

Query: 769  CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
             KN   ++    +      D     +++    +D     +KA N  G   + A + V+  
Sbjct: 2112 YKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA- 2170

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
                 +   F    Q++  KEK T+      T  P   + WY++   +   +    + D 
Sbjct: 2171 ----KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDR 2226

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
            +   L I  +D+  D+ DY CV        +  A++ ++   V FVK LQ   E  E  +
Sbjct: 2227 KVHFLSILTIDTS-DAEDYSCVLVEDENVKT-TAKLIVEGAVVEFVKELQ-DIEVPESYS 2283

Query: 946  VILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
              LEC  S   +  KWYHN  E+       I                 D G    ++  +
Sbjct: 2284 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343

Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY- 1063
            +T+  L +K      ++ L D +V E D+  LEV+++ E+ + VW +DG+ ++P    + 
Sbjct: 2344 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2403

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
              +K+ H+  L I + +  D G YS  +     +    V     ++IT L++  V +G K
Sbjct: 2404 VIDKQSHM--LLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTK 2461

Query: 1124 ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            A  E +++  D   V+W+ +  +I+  + +Q  + G KQ+L I      D G Y   VG 
Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGR 2521

Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242
             +    L+VE+  I   LR    +      +    VE+    +DV W  K   I+ + K+
Sbjct: 2522 VETNCNLSVEKIKIIRGLR---DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKY 2578

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
             + +  K   L +    +DD+ +YT    +  ++ KL V        + D      +   
Sbjct: 2579 KIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTD----QTVAES 2634

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
             +     +  A P    EW+ + K +    + +   D     L I   +  D G Y  ++
Sbjct: 2635 QEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKV 2693

Query: 1363 ENNCGHADVEMNVTILDK 1380
              +   A +++    + K
Sbjct: 2694 ATSKTSAKLKVEAVKIKK 2711



 Score =  176 bits (429), Expect = 5e-42
 Identities = 171/705 (24%), Positives = 309/705 (43%), Gaps = 56/705 (7%)

Query: 632  IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            IPP+F+K+      + EG+   LE R+       +AW     EI P  N  +  +++   
Sbjct: 9174 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNT-- 9231

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               VL++        G YT    N  G A     + IK   K+PP   + L  + V +GE
Sbjct: 9232 --LVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE-PKKPPVFDQHLTPVTVSEGE 9288

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808
             V LS  V G+    I W K  + +K     S        +L+ + V   D G Y  KA 
Sbjct: 9289 YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKAS 9348

Query: 809  NSEGIAETSAVITVEE-----PTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNP 860
            N  G   T + +T+++     P  + A       F++  Q I V EK T   +A+V  +P
Sbjct: 9349 NVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 9408

Query: 861  VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            +P++ W +     ++    +  +  G+  +L I +  ++ DSG Y+CVA N  G+     
Sbjct: 9409 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDT-TKTDSGLYRCVAFNEHGEIESNV 9467

Query: 920  RVTIDV----EKV-----TFVKH--LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
             + +D     EK+       +K   + K    EE +  I+E   +  V  K Y     + 
Sbjct: 9468 NLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKN--VDPKEYEKYARMY 9525

Query: 969  GM-DHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLV------VKETIP-EF 1019
            G+ D R ++Q                ++  I+   +D++    LV      + +T P   
Sbjct: 9526 GITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTL 9585

Query: 1020 IRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            I+ +++  V + + A+ E++I  N     + W +  E ++P  +K++    G    L ++
Sbjct: 9586 IKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPS-DKFEISIDGDRHTLRVK 9644

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
            N  + D+G Y  +      +A++TV+E  P     LQ+  + +G   T   + +  +   
Sbjct: 9645 NCQLKDQGNYRLVCGPHIASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSVPNVKS 9702

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
             WF++G  ++     +  ++ K  KL I D   +D G+Y+C+  + + +A L +E   I 
Sbjct: 9703 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQ 9762

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
            FT R+ + I+V  +  A    E+  +   VTWYK  + + +++K+   +D +   + I  
Sbjct: 9763 FTKRI-QNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHN 9821

Query: 1258 CTEDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292
             T DD+  Y+ +       +A+ST +L +   E      PP I D
Sbjct: 9822 VTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPD 9866



 Score =  174 bits (424), Expect = 2e-41
 Identities = 197/865 (22%), Positives = 337/865 (38%), Gaps = 48/865 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV 1284
             VTW KK+     T+    ++ V  + L IR    +D   Y+  + +     T  +KV V+
Sbjct: 18177 VTW-KKEDRDAPTKARIDVTPVGSK-LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 18234

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             + P    D E     K    +T              ++V  + +   + +  S  SK  S
Sbjct: 18235 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 18294

Query: 1345  LTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL---EIDSSSIN 1398
                K +   +  ++++  EN  G     +    +  LD   PPG P  L   ++D + ++
Sbjct: 18295 HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVS 18354

Query: 1399  ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             + W++P+  G S I  Y+VEYQE  T +WI  K +T  +  +  L+   +YRFR  A N 
Sbjct: 18355 LVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 18414

Query: 1459  VDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
             V +    +TT    +  + K+  P+VE   K ++ +  +    +    I  GVP P   W
Sbjct: 18415 VGLG-LPDTT--IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKW 18471

Query: 1516  YRDGKKLKTAK-ATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETS---CVVGIQ 1568
               DG ++KT +  T E                    Y+    N  G    +    V+ + 
Sbjct: 18472 TTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP 18531

Query: 1569  QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
               P   I+  D+  +H +   W       G P    I  K   +   D    +++    +
Sbjct: 18532 GPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTR--KDTWGVVSSGSSKT 18588

Query: 1629  VIRIKELKRSHSSKYTIEASNTAGT----SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
              ++I  L++     + + A N  G      S     K    P  P G  ++ +I+  + T
Sbjct: 18589 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 18648

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
             + W  P  DGG  +T Y +E+ E    +W++V         + +  L E   Y FRV A+
Sbjct: 18649 VSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAE 18707

Query: 1745  NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
             N  G S+ +  S+PI     +  P              E+  + W     +GGSPI+ Y 
Sbjct: 18708 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDK-SRETADLVWTKPLSDGGSPILGYV 18766

Query: 1804  VEIKQEG-KKWKXXXXXXXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
             VE ++ G  +W              R+  L     Y+FRI A N +G   P    + +  
Sbjct: 18767 VECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIA 18826

Query: 1860  GKTLTPPSQPRNFVVSESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
                L PP    +    +  +  V  T++          P   +  E K +  +    ++ 
Sbjct: 18827 KDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQ 18886

Query: 1918  VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
                 V E  I+     D   + ISA+N+ G      +Q   +      P  P   L++  
Sbjct: 18887 DLPRV-ELQIKEAVRADHGKYIISAKNSSG-----HAQGSAIVNVLDRPG-PCQNLKVTN 18939

Query: 1978  VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
             V       SW  P  +GG+ +  + +  R   +  W  V   DV T +    +L  N+ Y
Sbjct: 18940 VTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS-DV-TKRLIKANLLANNEY 18997

Query: 2038  MIRIYARNEIGLSEPLESDEPFKVI 2062
               R+ A N++G+   +E+  P   I
Sbjct: 18998 YFRVCAENKVGVGPTIETKTPILAI 19022



 Score =  171 bits (415), Expect = 2e-40
 Identities = 164/708 (23%), Positives = 296/708 (41%), Gaps = 36/708 (5%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT 1436
             +D P PPGKP + ++  +S+ + W +PE+ G + I  YV+E  +  T EW+ V + +  T
Sbjct: 14908 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 14967

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEP 1495
             Q  +  L     Y FR  AVN+   S+ SE ++   V+   K+  P+  + L+ I  T+ 
Sbjct: 14968 QHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD--PVLCREKLYPPSPPRWLEVINITKN 15025

Query: 1496  NEDIELTCIF--GGVPQPK-VTWYRDGKKL------KTAKATYENRXXXXXXXXXXXXXX 1546
               D++ T     GG P    +   RD ++        T K T                  
Sbjct: 15026 TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVA 15085

Query: 1547  XYKCIAFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
                 I  +D+ E+E S +         P   ++  D+ ++H V  +W       G P   
Sbjct: 15086 AENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQR 15144

Query: 1604  VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTL 1660
              +  K   +L         T       R+ ++      ++ + A N AG    S     L
Sbjct: 15145 YVIEKK-ERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 15203

Query: 1661  KVYDKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
              + D  S P  P+ +   +  R+ + I WKPP  +GG  +  Y +E       +W++V  
Sbjct: 15204 SIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 15263

Query: 1719  VD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXX 1776
                +D++    + +  + EY+ RV A N +G SE  E SE +V K     P+        
Sbjct: 15264 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDI 15323

Query: 1777  XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQ-KLSINTTY 1835
               I+ E + I   P  +    P + +  + K+     +         A ++   S+    
Sbjct: 15324 IVIEGEKLSIP-VPF-RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 15381

Query: 1836  Q-FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
               + I   N++G++   T+   +   K +  P   ++   S+ T  S  L W  PE +GG
Sbjct: 15382 GIYTITLENKLGSA---TASINV---KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGG 15435

Query: 1895  SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
             +PI +Y++E +    +++  +++ G +     ++++    E  FR+ A N VG     E 
Sbjct: 15436 TPILHYVLERREAGRRTYIPVMS-GENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL 15494

Query: 1955  QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
             ++  + +    P  P   +E+    +  +  +W  P +DGG+ ++GY I      +  W 
Sbjct: 15495 KNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWK 15554

Query: 2015  EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
                +  V  L +  + L E   Y  R+ A N  G+SEP  +  P K +
Sbjct: 15555 RCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV 15602



 Score =  166 bits (404), Expect = 5e-39
 Identities = 246/1096 (22%), Positives = 440/1096 (40%), Gaps = 86/1096 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P   ++ ++Q V +GSD     R+V  P+P+  W   G +I   + I      D    C 
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCE 2135

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I +V      +  V A+N  GE S    L ++   K+     + L+ ++ ++ +++ 
Sbjct: 2136 -LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA--KQLITFTQELQDVVAKEKDTMA 2192

Query: 754  LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
                    P   + W K+   V         SD   H ++IL      D   Y+      
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL-TIDTSDAEDYSCVLVED 2251

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            E + +T+A + VE    E      F+   Q+I V E  + +L   V+   +    WY N+
Sbjct: 2252 ENV-KTTAKLIVEGAVVE------FVKELQDIEVPESYSGELECIVSPENIEG-KWYHND 2303

Query: 871  -EIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             E+ S  + TIT     +N  L + +V  E D G+Y  V     GK +   ++ +    +
Sbjct: 2304 VELKSNGKYTITSRRGRQN--LTVKDVTKE-DQGEYSFVID---GKKT-TCKLKMKPRPI 2356

Query: 929  TFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
              ++ L    +  EG  V LE + S  +V   W  + +E+   D   I+ + +       
Sbjct: 2357 AILQGL-SDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046
                 D G     +     ST   V     + I  L+D  V E   A+LE +++  +   
Sbjct: 2416 DMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTS 2475

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
            V W  + E IKP  ++     +G  ++L I  T   DEG Y  I+        ++V ++ 
Sbjct: 2476 VKWYLNDEQIKP-DDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI- 2533

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRW-FKDGSEIQFSNHIQLTIDGKKQKLKI 1165
             +II  L++    +     FE+EL+     V W FKD  EI+ S+  ++   GK  KL +
Sbjct: 2534 -KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD-KEIKPSSKYKIEAHGKIYKLTV 2591

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
             +   DD G+Y+   G +  +  LTV   +I+  L       V  + +A    E+ +   
Sbjct: 2592 LNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQ---TVAESQEAVFECEVANPDS 2648

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
               W +    +  T      SD  KR LII     DD  EYT  +  +K++ KLKVE V 
Sbjct: 2649 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAV- 2707

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
               KI    +   +    D    V+         +WI N  +++  +    S+     SL
Sbjct: 2708 ---KIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSL 2764

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
             IK     D  +Y  RL      A + +  V I+ KP      ++  ++++++       
Sbjct: 2765 RIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK-----DVTALENATVAFEVSVS 2819

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             +T      +  VE +  D    +S + + K    +QN+  + +  + A  V +++    
Sbjct: 2820 HDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLM--LQNISPSDAGEYTA-VVGQLECK-- 2874

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
                   K+  ET      + K +KNI     +     C       P + W ++G +++ 
Sbjct: 2875 ------AKLFVETL----HITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2923

Query: 1525 A---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
            +   K   + +                Y  +  ND  +V  +  V      +IT   +DI
Sbjct: 2924 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND--QVSATLTV---TPIMITSMLKDI 2978

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
              + K    + VT   EGI      W KNG ++++  +  + TK+ T  + I+ +    +
Sbjct: 2979 NAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDA 3035

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEWKPPLD 1692
            + YT  A     T+++ V  +  +        K  + +  +   E+S   +T++W    D
Sbjct: 3036 ADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMK--D 3093

Query: 1693 DGGLELT-KYAIEKHE 1707
            D  L++T +  I+K +
Sbjct: 3094 DQELQITDRIKIQKEK 3109



 Score =  165 bits (401), Expect = 1e-38
 Identities = 188/777 (24%), Positives = 330/777 (42%), Gaps = 67/777 (8%)

Query: 1316  QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             +P+ EWIV +  ++ CK+          S+T K +E  +  ++++R EN  G     ++ 
Sbjct: 15772 KPDSEWIVVTSTLRHCKY----------SVT-KLIEGKEY-LFRVRAENRFGPGPPCVSK 15819

Query: 1376  TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
              ++ K     P  P KP + ++ S+S+ + W+EP++ G S I+ Y +E +E+++T W  V
Sbjct: 15820 PLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTHWSRV 15878

Query: 1431  KN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
                 +   + ++  L    +Y FR  A N       S  ++            P + +  
Sbjct: 15879 NKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT 15938

Query: 1489  KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXX 1544
                +T    + E     GG    ++  Y   K+L    + ++ T +              
Sbjct: 15939 DTSSTTIELEWEPPAFNGG---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 15995

Query: 1545  XXXYKC--IAFNDHGEV---ETSCV-VGIQQKPVITISNEDIKQKHKV--GDEWLVTAVI 1596
                YK    A N  GE    ET  V V   Q+P     +  +K   ++  G    + AV+
Sbjct: 15996 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVV 16055

Query: 1597  EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
              G P P  +W K   +L+ D+        K+ +I IK+  R    +Y I A+N+ G+   
Sbjct: 16056 TGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELI-IKDALRKDHGRYVITATNSCGSKFA 16114

Query: 1657  EVTLKVYDKPSKPEGPVI-MREI--SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
                ++V+D P    GPV+ ++ +  +R+   + W  P DDGG E+T + IE+ +   + W
Sbjct: 16115 AARVEVFDVP----GPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTW 16170

Query: 1714  IKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772
              +  + +R   + C I  L E  EY FRVIA+N  G    +E  PI+    L  P+    
Sbjct: 16171 RQPIETER---SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPER 16227

Query: 1773  XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829
                       ++ + W     NGGSPI  Y +E ++  K   +             ++ L
Sbjct: 16228 LTYTER-TKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENL 16286

Query: 1830  SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
               +  Y+FR+ A NEIG S P    + +     + P  + R  V  ++           P
Sbjct: 16287 DEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIP 16346

Query: 1890  ESNGGSPI-------TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
                 G P+          +IE  T   +   + V+   +  E  I     +D+  + ++A
Sbjct: 16347 ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTA 16406

Query: 1943  ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
              N +G    +  ++V +E +   PSPP   L +  + +     +W  P  +GG+ +  Y 
Sbjct: 16407 SNRLG----SVFRNVHVEVYDR-PSPP-RNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 16460

Query: 2003  IAIRDVT--KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             I  RD +  K  W EV    V   ++ I  L  N  Y  R+ A N+ G+S+  +SD+
Sbjct: 16461 IDKRDASRKKAEWEEVTNTAVEK-RYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 16516



 Score =  165 bits (401), Expect = 1e-38
 Identities = 221/972 (22%), Positives = 399/972 (41%), Gaps = 75/972 (7%)

Query: 1128  IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY-SCEV-GNSKC 1185
             IE+ K D L  W K  +E        +T     ++ K     ++ AG+  SCEV G  K 
Sbjct: 29217 IEMCKAD-LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKA 29275

Query: 1186  TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245
                LT  E  I+   +    +   A+   ++  +    T    W K  S +  + +  + 
Sbjct: 29276 VDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ-GRPTPTAVWSKPDSNL--SLRADIH 29332

Query: 1246  SDVKKRTLIIRKCTEDDQCEYTCVLLD---AKSTT-KLKVEVVEFPPKIVDYEREYRIKR 1301
             +     TL +  C  +D  +YT  + +   +KS T  +KV     PP  + ++    + R
Sbjct: 29333 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD---VTR 29389

Query: 1302  GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAGI-- 1357
             GS  TL+ D    P  +    ++  +++K + ++ S  + S+  +  I KV +   G+  
Sbjct: 29390 GS-ATLMWDA---PLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPY 29445

Query: 1358  -YKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
              +++   N  G  +  EM   I+  ++P+PP + ++++   SS  + W +P++ G S I 
Sbjct: 29446 YFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRIT 29505

Query: 1414  YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
              Y++E ++  +  W+   +  +   +++ L   + Y FR  A N+   S+  E      +
Sbjct: 29506 GYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV-I 29564

Query: 1474  IKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKA 1527
             IKE +I+       + N  IT +      +     G P PKVTW  +  +LK     +  
Sbjct: 29565 IKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSIT 29624

Query: 1528  TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
             T ++R               Y     N  G    S  V +  +P       ++     V 
Sbjct: 29625 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVS---SVS 29681

Query: 1588  DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKY--- 1643
              E   + V+    P +    +  N +   +E   T  +   S ++  ++K +H +KY   
Sbjct: 29682 AE---SCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEY 29738

Query: 1644  --TIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
                + + N  G S    +  +     +  PS P  P +   +S  +++I W+ P  DGG 
Sbjct: 29739 SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVY-HVSANAMSIRWEEPYHDGGS 29797

Query: 1697  ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755
             ++  Y +EK E +   W+K   V      Y +  L E  EY FR  A N  G S+A E S
Sbjct: 29798 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 29857

Query: 1756  EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---- 1811
              PI+ +  +D P           +   +V + W     +GGS ++ Y +E K   +    
Sbjct: 29858 RPIMAQNPVDAPG----RPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 29913

Query: 1812  KWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQ 1868
             +W              +  LS   TY+FR+ A+N  G  S    S   +T      PP  
Sbjct: 29914 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 29973

Query: 1869  PRNF-VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV--GGSVHEH 1925
               +  +  +  +           + GG P    II  K  K     + V++   G     
Sbjct: 29974 ELDARLHGDLVTIRAGSDLVLDAAVGGKPEPK-IIWTKGDKELDLCEKVSLQYTGKRATA 30032

Query: 1926  CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNIVM 1984
              I+     D   + ++ +N  G    T++ SV ++    + SP P   L +  V      
Sbjct: 30033 VIKFCDRSDSGKYTLTVKNASG----TKAVSVMVK---VLDSPGPCGKLTVSRVTQEKCT 30085

Query: 1985  TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              +W  P+ DGGA +  Y +  R+ ++  W+ V + +  TL + +  L +N+ Y+ R+ A 
Sbjct: 30086 LAWSLPQEDGGAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAV 30144

Query: 2045  NEIGLSEPLESD 2056
             N+ G   P+ES+
Sbjct: 30145 NKYGPGVPVESE 30156



 Score =  163 bits (395), Expect = 6e-38
 Identities = 179/733 (24%), Positives = 293/733 (39%), Gaps = 51/733 (6%)

Query: 1358  YKLRLENNCGHADVEMN---VTILDKPSPPGKP-NILEIDSS--SINICWDEPENTGNST 1411
             ++++ EN  G  +  +    V   D   PPG P N   +D++  SI + W +P   G + 
Sbjct: 19395 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 19454

Query: 1412  IIYYVVEYQE--IDTTE---W---ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
             II YVVE +    D +    W    +   + + + ++ +L  N  Y FR  A N+V I  
Sbjct: 19455 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 19514

Query: 1464  ASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--- 1517
              +E  E  K  KE  ++ P ++      K +       I L  I  G P PKVTW +   
Sbjct: 19515 PAELKEAIKP-KEI-LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGI 19572

Query: 1518  DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITI 1575
             D    K      +                 Y     N  GE      V +     PV  +
Sbjct: 19573 DNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 19632

Query: 1576  SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKE 1634
                D+  K      W   A  E     +V  Y    +  + K ++  T E K +   +  
Sbjct: 19633 KVSDV-TKTSCHVSW---APPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTN 19688

Query: 1635  LKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKP 1689
             L   +   + + A N  G    + V   +   D  S+P+ P  + + E+++ S T+ W P
Sbjct: 19689 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 19748

Query: 1690  PLDDGGLELTKY--AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
             PL DGG ++  Y  +  + E   +RW + + V +D+ +  +  L E  +Y FRV A+N V
Sbjct: 19749 PLRDGGAKIDGYITSYREEEQPADRWTEYS-VVKDL-SLVVTGLKEGKKYKFRVAARNAV 19806

Query: 1748  GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
             G S   E+E +       +P              + + I      K    P   +K    
Sbjct: 19807 GVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK--PHPTCKWKKGED 19864

Query: 1808  Q--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
             +                   I+ ++   +  + + A N  GT    T   K+ +     P
Sbjct: 19865 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTD---TQKIKVVVMDAPGP 19921

Query: 1866  PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
             P  P  F +S+  + + +L W  P  +GGS ITNYI+E   V    W  +  +       
Sbjct: 19922 PQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDW--VTALASVTKTS 19977

Query: 1926  C-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
             C +  +    E IFR+ AEN  G+S P  S  +  +    VPS P     +  V  + + 
Sbjct: 19978 CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP-KNARVTKVNKDCIF 20036

Query: 1985  TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              +W  P+ DGG+P++GY I  ++    +W++     V + ++    L E   Y  RIYA 
Sbjct: 20037 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 20096

Query: 2045  NEIGLSEPLESDE 2057
             N+ G S P +  E
Sbjct: 20097 NKAGSSPPSKPTE 20109



 Score =  162 bits (393), Expect = 1e-37
 Identities = 159/704 (22%), Positives = 283/704 (40%), Gaps = 35/704 (4%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITK 1435
             +++PSPP      +   SS+ + W+ P   G S I+ Y++E  E     WI  ++K + +
Sbjct: 14216 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 14275

Query: 1436  TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE- 1494
                 +  L+  + Y +R  A N+  +SD SE      +  +     PT++        E 
Sbjct: 14276 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILG--PLTADDAFVEPTMDLSAFKDGLEV 14333

Query: 1495  --PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
               PN  I +     G P+P  TW    K L+T                        K I 
Sbjct: 14334 IVPNP-ITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI- 14391

Query: 1553  FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWY 1607
             +    E     + G  +  V  I+     ++ K GD    +  +   PP +     +  Y
Sbjct: 14392 YTLKLENRVKTISG--EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGY 14449

Query: 1608  KNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVY 1663
                 +  + K +       T +   + +L +     + + A N  G      V+  + + 
Sbjct: 14450 VVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 14509

Query: 1664  DKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
                + P+ P  V  R+ +  S+ + W PP +DGG  +  Y +E+    +++W+   +   
Sbjct: 14510 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 14569

Query: 1722  DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780
             + +   +  L E   Y +RV A N  G S+ +  +E I      + P           + 
Sbjct: 14570 ETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 14628

Query: 1781  NESVYITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
              ++      P+   G   P I + K + I ++ K+             I     + T  +
Sbjct: 14629 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 14688

Query: 1838  RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
              I A N  G +   T+  ++ +   L  P  P  F +++ T+ S  L W  P  +GGS I
Sbjct: 14689 IIEAVNVCGRA---TAVVEVNV---LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI 14742

Query: 1898  TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
             TNY++E +    + W K+ +     +    + I  K E IFR++AEN  GV  P ++  +
Sbjct: 14743 TNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK-EYIFRVAAENMYGVGEPVQASPI 14801

Query: 1958  RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
               +     P PPT  LE   +  + V  +W  P+ DGG+P+ GY +   D     W+   
Sbjct: 14802 TAKYQFDPPGPPTR-LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN 14860

Query: 2018  KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             K+ V    + ++ L+    Y  R+ A N  G  +P +S EP  +
Sbjct: 14861 KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 14904



 Score =  161 bits (391), Expect = 2e-37
 Identities = 238/1087 (21%), Positives = 450/1087 (41%), Gaps = 84/1087 (7%)

Query: 629   LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVA 683
             L+ +P  F K+ K   + E    GS  + EC LV+       W+  G  I    ++  +A
Sbjct: 12037 LKAVPLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIA 12095

Query: 684   IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741
                D  ++     I +V+    G YT V    N+E  ++  +V+     E+ P + ++ L
Sbjct: 12096 DGKDRKLH-----IIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTL 12145

Query: 742   KSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796
             +  + V +G+ + LS ++  N    + W K+ K V   P +      G   ++TI     
Sbjct: 12146 EEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADD 12203

Query: 797   VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
               D G YT+  EN+  +  +S V  VE   +   +P       ++  VK KGT      +
Sbjct: 12204 T-DAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP------IRDQHVKPKGTAIFACDI 12256

Query: 857   TRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              ++  P+I W++  + I   P++      DG ++ L I N   E D  +Y   A    GK
Sbjct: 12257 AKD-TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPE-DIAEY---AVEIEGK 12311

Query: 915   SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973
               + A++T+   +V  +K ++      E ++   + + S   +  +W    + +      
Sbjct: 12312 R-YPAKLTLGEREVELLKPIE-DVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTC 12369

Query: 974   EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
             EI  EG               G +     +  T+ +L VKE   +F   L+D  V E+  
Sbjct: 12370 EIKAEGGKRFLTLRKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQ 12429

Query: 1034  AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
             A  E  +  E A+V+W +  +IIK   +K+D    G    L I ++   DEG Y+  +  
Sbjct: 12430 ARFECVLTRE-ANVIWSKGPDIIK-SSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG 12487

Query: 1094  ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
             +  +A + V  +  + ++ L++Q V +G  ATF  EL+     V WFK+ +++  S  + 
Sbjct: 12488 KKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL 12547

Query: 1154  LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
             ++ +GK  KL++ +  LDD  +   +V     TA L V E    FT++L +   V  + +
Sbjct: 12548 ISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKD-E 12606

Query: 1214  AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
               L  E+  + + V W+K    I  + K+++ +D  +R L I+K    D+ EY C     
Sbjct: 12607 ITLKCEV-SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTD 12665

Query: 1274  KSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQ-AFPQPNDEWIVNSKIIKKC 1331
             K+   + VE      +++  E+  Y ++     T   + + + P  + +W +  + +   
Sbjct: 12666 KTKANVTVEA-----RLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTAS 12720

Query: 1332  KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
                +   D K   L +   +    G    +  N    A++++    L   +P     + E
Sbjct: 12721 PDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFE 12780

Query: 1392  IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQN--LKTNSS 1448
              D +       E E +       ++   QEI   +    +K+ TK    I++   +  + 
Sbjct: 12781 KDEAKF-----ECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 12835

Query: 1449  YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
             Y F A            + T    +I+  +++  T   PLK++T +  E    T      
Sbjct: 12836 YMFEA----------EDKHTSGKLIIEGIRLKFLT---PLKDVTAKEKESAVFTVELSH- 12881

Query: 1509  PQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
                +V W+++ ++L T ++ + ++                   I     G    + +  +
Sbjct: 12882 DNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL 12941

Query: 1568  QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
             +  P  T   +D     K  DE ++   I     P V W+K+G +++  K   I    K 
Sbjct: 12942 EGDPYFTGKLQDYTGVEK--DEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK 12998

Query: 1628  SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-SRESVTIE 1686
              ++ +K+  +S   +YT +     GT      L + D+  K   P+   E+   E+   E
Sbjct: 12999 RMLILKKALKSDIGQYTCD----CGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFE 13054

Query: 1687  WKPPLDD 1693
              +   DD
Sbjct: 13055 TEISEDD 13061



 Score =  161 bits (390), Expect = 3e-37
 Identities = 169/711 (23%), Positives = 284/711 (39%), Gaps = 48/711 (6%)

Query: 1378  LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITK 1435
             LD   PPGKP  L I   ++ + W +PE TG   I  Y+VE +++    W+     NI +
Sbjct: 22281 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 22340

Query: 1436  TQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLK---NI 1491
              + ++  L  +++Y FR  A N    IS  SE ++   +     +++P ++  +K    +
Sbjct: 22341 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD--AITCRDDVEAPKIKVDVKFKDTV 22398

Query: 1492  TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXX---XXX 1547
               +  E   L     G P P + W +DGK+L+ TAK   +                    
Sbjct: 22399 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGA 22458

Query: 1548  YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
             Y   A N  G  +    V +  +P      E      +V  E     V+   PP +    
Sbjct: 22459 YTLTATNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEVTSE---KCVLSWFPPLDDGGA 22512

Query: 1608  KNGNKLENDKEY------NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSV 1656
             K  + +   +E       N+ ++ + + +++ +L + +   + + A N  G      S  
Sbjct: 22513 KIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 22572

Query: 1657  EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
              + +  Y  P  P+ P +   I+++S+ + W  P  DGG E+  Y +E+ +    RWIK 
Sbjct: 22573 VLAVNPYGPPDPPKNPEVTT-ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKC 22631

Query: 1717  ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
                      Y +  L E  EY FR++A+N  G S    + P                   
Sbjct: 22632 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRV 22691

Query: 1777  XXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXAR---IQKLSIN 1832
                   S+ I W     +GGS I  Y VEI   E  +W+         A    I  L+ N
Sbjct: 22692 LDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTEN 22751

Query: 1833  TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES-TSRSV-TLKWTEPE 1890
               Y+ RIYA N  G   P            + PP    +  + +  T R+  TL+   P 
Sbjct: 22752 QEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPI 22811

Query: 1891  SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-NIKEKDEIIFRISAENTVGVS 1949
                 +P   +  +     G+S  K      S +   I  N+   D   + ++ EN+ G  
Sbjct: 22812 KGRPAPEVKWARDH----GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG-- 22865

Query: 1950  LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
               ++S  V +    T P PP   L+++ V    V  +W  P  DGG+ +  Y +  R+ T
Sbjct: 22866 --SKSAFVNVRVLDT-PGPPQ-DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 22921

Query: 2010  KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             +  +  V   + +   + +  L E  +Y  R+ A NE G+  P E+ E  K
Sbjct: 22922 RKAYSTVA-TNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK 22971



 Score =  160 bits (389), Expect = 3e-37
 Identities = 192/881 (21%), Positives = 342/881 (38%), Gaps = 84/881 (9%)

Query: 1232  KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPK 1289
             K  V +  E   L +      +II +C      +Y+    +   + T   +V+V++ P  
Sbjct: 16782 KDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGP 16841

Query: 1290  IVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKS 1342
               D        + SD+T      ++  P+D+       +++  + I     TK + D  S
Sbjct: 16842 PKDL-------KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGS 16894

Query: 1343  ASLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTILDK---PSPPGKPNILEIDSSS 1396
              +  +  + +     +++R EN  G     +     T  D    P PP K  I  I  ++
Sbjct: 16895 TTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT 16954

Query: 1397  INICWDEPENTGNSTIIYYVVEYQEIDTT-----EW--ISVKNITKTQTSIQNLKTNSSY 1449
             +++ W  P+N G S + +Y+VE    D T      W   + +++ + Q ++++L     Y
Sbjct: 16955 VHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEY 17014

Query: 1450  RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGV 1508
              FR  AVN   +S  S T        +     P+++  LK  +  E   ++ +     GV
Sbjct: 17015 EFRVKAVNAAGVSKPSATVGPCDC--QRPDMPPSID--LKEFMEVEEGTNVNIVAKIKGV 17070

Query: 1509  PQPKVTWYR------DGKK-----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
             P P +TW++      D K+         K   ++                Y   A N+ G
Sbjct: 17071 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 17130

Query: 1558  EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
                    + +  +P   +    IK +    D+      +   PP +    K  N +   +
Sbjct: 17131 TASKEMRLNVLGRPGPPVG--PIKFESVSADQ----MTLSWFPPKDDGGSKITNYVIEKR 17184

Query: 1618  EYN------ITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKVYDKP 1666
             E N      ++++ K     I +L   H   + I A N  G      S  E    ++  P
Sbjct: 17185 EANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVP 17244

Query: 1667  SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE- 1724
               P+ P +   ++R S+T+ W+ P  DGG  +T Y +E  +  + RW +V  D  + +  
Sbjct: 17245 GAPDKPTV-SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 17303

Query: 1725  --TYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
               +Y +  L E  +Y FRV A N  G   A L S+P   +  +  P              
Sbjct: 17304 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWT--K 17361

Query: 1782  ESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFR 1838
              S  + W P  K+GGS +  Y VE K+EGK +W+          +  +  L     Y+FR
Sbjct: 17362 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 17421

Query: 1839  IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSP 1896
             + A N  G   P    D I +   L  P    +  V +         ++     S    P
Sbjct: 17422 VSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 17481

Query: 1897  ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
                + +  +T+  ++  +   +  S+    I+N +   + ++ + A+N  G     E + 
Sbjct: 17482 TVTWNMNERTLPQEATIETTAISSSM---VIKNCQRSHQGVYSLLAKNEAG-----ERKK 17533

Query: 1957  VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
               +     VP P   P     + +     +W +PE DGG+P+  Y I  R+  +  W  V
Sbjct: 17534 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 17593

Query: 2017  GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
                 V      ++ L +   Y  RI A N IG+   +E+ E
Sbjct: 17594 -TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE 17633



 Score =  159 bits (386), Expect = 8e-37
 Identities = 115/396 (29%), Positives = 184/396 (46%), Gaps = 15/396 (3%)

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             D P +PE  VI    +R +VT++WK P  DGG ++T Y +EK +  + RW+K +  +   
Sbjct: 25531 DPPGRPEAIVI----TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE 25586

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVG-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDN 1781
               + +  L E+  Y FRVIA+N  G FSE  +S   I  +  +D P+          I  
Sbjct: 25587 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 25646

Query: 1782  ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
              +   T+       G PI D  V   ++GK+ +         + IQK ++      R   
Sbjct: 25647 HAGE-TFVLEADIRGKPIPD--VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 25703

Query: 1842  RNEIG--TSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPIT 1898
                I   +++  T    IT+ K L  P  P     V+  T+    L W  P  +GG+ I+
Sbjct: 25704 GQYILKLSNVGGTKSIPITV-KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 25762

Query: 1899  NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             +YIIE +     SWT++ T   +++ + +  +   +E IFR+ A N  G+  P ES  V 
Sbjct: 25763 HYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 25821

Query: 1959  LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
                    P PP+ P E+  +  + ++ +W  P  DGG  + GY +  RD     W +  K
Sbjct: 25822 ACNPYKPPGPPSTP-EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 25880

Query: 2019  VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
               +  L+  +  L+E H+Y  R+ A N  G+ EP E
Sbjct: 25881 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 25916



 Score =  158 bits (384), Expect = 1e-36
 Identities = 122/395 (30%), Positives = 175/395 (44%), Gaps = 18/395 (4%)

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             D P +PE  ++    +R SVT++WK P  DGG ++T Y +EK E    RW+K A     +
Sbjct: 23367 DPPGRPEAIIV----TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK-ASFTNII 23421

Query: 1724  ETYC-IQKLNENCEYMFRVIAQNPVG-FSEALESE-PIVIKTALDVPSXXXXXXXXXXID 1780
             +T+  +  L E+  Y FRVIA+N  G FSE  ES   I  +  +D P           I 
Sbjct: 23422 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIV 23481

Query: 1781  NESVYITWFPSEKNGGS-PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839
               +       ++  G   P I +   IK + +                 LS+      R+
Sbjct: 23482 VHAGESFKVDADIYGKPIPTIQW---IKGDQELSNTARLEIKSTDFATSLSVKDAV--RV 23536

Query: 1840  YARNEIGTSLPYTSDDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPI 1897
              + N I  +     +  +T+  K L  P  P    V+S  T+   TL W  P  +GGS I
Sbjct: 23537 DSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 23596

Query: 1898  TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
              NYI+E +      WT +V          +  + E +E  FRI A N  GV  P ES+ V
Sbjct: 23597 INYIVERRETSRLVWT-VVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPV 23655

Query: 1958  RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
               +    VP  P AP E+  V  + ++  W  P  DGG+ +LGY +  RD     W    
Sbjct: 23656 VAKNPFVVPDAPKAP-EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCH 23714

Query: 2018  KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             K  +  L+  +  L ENH Y  R+ A N  GLSEP
Sbjct: 23715 KRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 23749



 Score =  158 bits (384), Expect = 1e-36
 Identities = 113/414 (27%), Positives = 182/414 (43%), Gaps = 14/414 (3%)

Query: 1666  PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
             P KP+ P +  + +R SV++ W  P D+GG ++T Y IE  + D + W K       +  
Sbjct: 30960 PGKPQNPRVT-DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 31018

Query: 1726  YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXID-NES 1783
             Y +  L +  EY FRV+A N  G  E  E    V +   L+ P           I   + 
Sbjct: 31019 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 31078

Query: 1784  VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
               I      K    PI  +  E +   K+             I++     +  + +   N
Sbjct: 31079 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 31138

Query: 1844  EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
             + G    Y    K+ +  +   P  P  +   +   RSV + W  P  +GG+ I  YI+E
Sbjct: 31139 KCGKKAVYI---KVRVIGSPNSPEGPLEY--DDIQVRSVRVSWRPPADDGGADILGYILE 31193

Query: 1904  FKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEK 1961
              + V   +W  I + V G+     ++ +KE  E  FR+SAEN  G+S P +S+  V  + 
Sbjct: 31194 RREVPKAAWYTIDSRVRGT--SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 31251

Query: 1962  HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                 P PP+ P E+  V  + V  SW  P+ DGG+ + GY I  ++ +   W+   K  +
Sbjct: 31252 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 31311

Query: 2022  NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075
              T  + +  L  +  Y  RI A+N++GLSE   + EP  V+  +      +PGE
Sbjct: 31312 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEP--VVCKDPFDKPSQPGE 31363



 Score =  156 bits (378), Expect = 7e-36
 Identities = 106/368 (28%), Positives = 166/368 (45%), Gaps = 15/368 (4%)

Query: 1623  TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
             +K+  S +R+++  R     Y I+  N  G +    T+ V D P  P    +  +I + S
Sbjct: 15686 SKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN-FVFEDIRKTS 15744

Query: 1683  VTIEWKPPLDDGGLELTKYAIEKHE---PDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             V  +W+PPLDDGG E+  Y +EK +   PD+  WI V    R  + Y + KL E  EY+F
Sbjct: 15745 VLCKWEPPLDDGGSEIINYTLEKKDKTKPDSE-WIVVTSTLRHCK-YSVTKLIEGKEYLF 15802

Query: 1740  RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             RV A+N  G      S+P+V K     P             N S+ + W    K+ GSPI
Sbjct: 15803 RVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSN-SMLVKW-NEPKDNGSPI 15860

Query: 1800  IDYKVEIKQ-EGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
             + Y +E ++     W            A +  L    TY FR+ A N  G        D 
Sbjct: 15861 LGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 15920

Query: 1857  ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
              T    ++PP  P   V ++++S ++ L+W  P  NGG  I  Y ++ + V    W++  
Sbjct: 15921 KTAHDPISPPGPPIPRV-TDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCT 15979

Query: 1917  TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
                  V ++ ++ I+E  +   R+SA N  G   P E+Q V +   A    PP   L++ 
Sbjct: 15980 EKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPAVELDVS 16036

Query: 1977  MVGSNIVM 1984
             + G   +M
Sbjct: 16037 VKGGIQIM 16044



 Score =  155 bits (377), Expect = 1e-35
 Identities = 198/880 (22%), Positives = 337/880 (38%), Gaps = 48/880 (5%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284
             +TW K    + D     + S      L      + D  +Y   L ++  K    + V+V+
Sbjct: 20652 ITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 20711

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             + P   V+   +   K  + VT          P   ++V  +  ++   +  + +    S
Sbjct: 20712 DTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS 20771

Query: 1345  LTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
               +  +E   +  +++  EN  G  D       V     P P     +  +  SS +I W
Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGW 20831

Query: 1402  DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              +P + G S II YVV++   +  +W  V      Q S ++L     Y FR  A NE   
Sbjct: 20832 KKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGE 20890

Query: 1462  SDASETTEYYKVIKETKIQSPTVE-KPLKNI--TTEPNEDIELTCIFGGVPQPKVTWYRD 1518
                SE T    V+    + +P ++ K L ++    + N +  L     G P P V+W + 
Sbjct: 20891 GTPSEIT----VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 20946

Query: 1519  GKKLKT-AKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
                L T  + + E+                   Y     N  G  E +  + +  KP I 
Sbjct: 20947 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 21006

Query: 1575  IS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
                   D      +  +W       G      I  K  +   N+K     +  + +  R+
Sbjct: 21007 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS--VNNKWVTCASAVQKTTFRV 21064

Query: 1633  KELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
               L       + + A N  G      S   V    +D P  P  P I+ ++  +SV++ W
Sbjct: 21065 TRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV-DVRHDSVSLTW 21123

Query: 1688  KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
               P   GG  +T Y +E  E ++  W +       +  + +  L E  EY FRV+A N  
Sbjct: 21124 TDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLA 21183

Query: 1748  GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
             G  + +L SEP+V    +D P           I   SV + W   + +GG  +  Y VE 
Sbjct: 21184 GVGKPSLPSEPVVALDPIDPPG----KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEK 21239

Query: 1807  KQ-EGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKT 1862
             +    K W              +  L     Y+FRI A+N  G  S P  S + I     
Sbjct: 21240 RDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDE 21299

Query: 1863  LTPPSQPRNFVVSES-TSRSVTLKWTEPESNGGSPI--TNYIIEFKTVKGKSWTKIVTVG 1919
                P+   +  + +  T ++         S  G P+  +++    K ++    T+I +  
Sbjct: 21300 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 21359

Query: 1920  GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
              S     I+    KD   + I+A N  G    T+ + V++     VP PP  P+EI  V 
Sbjct: 21360 TS-SMLTIKYATRKDAGEYTITATNPFG----TKVEHVKVTV-LDVPGPP-GPVEISNVS 21412

Query: 1980  SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
             +     +W  P  DGG+P+  Y +  R+ ++ +W  V + D+ + +     L + + Y+ 
Sbjct: 21413 AEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIF 21471

Query: 2040  RIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
             R+ A N  G  EP++S EP K++   G     E  E + V
Sbjct: 21472 RVSAVNHYGKGEPVQS-EPVKMVDRFGPPGPPEKPEVSNV 21510



 Score =  155 bits (376), Expect = 1e-35
 Identities = 180/814 (22%), Positives = 322/814 (39%), Gaps = 64/814 (7%)

Query: 1300  KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
             K  +D+   V  +    P   +IV  + +++          K    T+  +      +++
Sbjct: 15024 KNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFR 15083

Query: 1360  LRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
             +  EN  G +D  E+  ++L K     P PP    ++++    +++ W+ P+N G   I 
Sbjct: 15084 VAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 15143

Query: 1414  YYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
              YV+E +E   T W+          +  + ++   +  +F+  A NE  +   SE TE  
Sbjct: 15144 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 15203

Query: 1472  KVIKETKIQSPTVEKPLKN-------ITTEPNEDIELTCIFGG----VPQPKVTWYR-DG 1519
              +   T   SP ++  + +       I  +P E    + I G      P     W R + 
Sbjct: 15204 SIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 15263

Query: 1520  KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNE 1578
             + +K  K   E                    I  ++  E+  + V      KP I +   
Sbjct: 15264 RPIKDLKFKVEE--GVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 15321

Query: 1579  DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
             DI      G++  +      +P P V W+K+G +++      +     ++ + + +  R+
Sbjct: 15322 DIIVIE--GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA 15379

Query: 1639  HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
              +  YTI   N  G+++  + +KV   P  P   +   +I++ S  + W+PP  DGG  +
Sbjct: 15380 DAGIYTITLENKLGSATASINVKVIGLPG-PCKDIKASDITKSSCKLTWEPPEFDGGTPI 15438

Query: 1699  TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
               Y +E+ E     +I V   +  + ++ ++ L  N EY FRV A N VG  E +E +  
Sbjct: 15439 LHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP 15497

Query: 1759  VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWK--X 1815
             VI      P              E++ ITW P   +GGS I+ Y +E I +  ++WK   
Sbjct: 15498 VIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCN 15557

Query: 1816  XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-V 1874
                        + L     YQFR+ A N  G S P  +       K + P   P+  +  
Sbjct: 15558 EHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT---KAVDPIDAPKVILRT 15614

Query: 1875  SESTSRSVTLKWTEPESNGGSPITNYI-----IEFKTVKGKSWTKIVTVGGSVHEH---- 1925
             S    R   +      S    P   +I     I  + +K ++   +    G V E     
Sbjct: 15615 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 15674

Query: 1926  -------CIENIKE-KDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976
                     I+N K+ + ++  R S     G+  +  E+     +   TV    T    I 
Sbjct: 15675 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 15734

Query: 1977  MVGSNI----VMTSWGTPEWDGGAPLLGYNIAIRDVTK--TMWMEVGKVDVNTLKFNIRD 2030
              V  +I    V+  W  P  DGG+ ++ Y +  +D TK  + W+ V    +   K+++  
Sbjct: 15735 FVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTK 15793

Query: 2031  LSENHTYMIRIYARNEIG-----LSEPLESDEPF 2059
             L E   Y+ R+ A N  G     +S+PL + +PF
Sbjct: 15794 LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF 15827



 Score =  153 bits (370), Expect = 7e-35
 Identities = 116/432 (26%), Positives = 195/432 (45%), Gaps = 20/432 (4%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVTIEWK 1688
             + + L+     ++ + A N  G        + Y    P  P G      + R  +T++W 
Sbjct: 24410 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 24469

Query: 1689  PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPV 1747
              P+ DGG  +T Y +EK +  + RW+K A     +ET + +  L E+  Y FRVIA+N  
Sbjct: 24470 KPVYDGGSMITGYIVEKRDLPDGRWMK-ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 24528

Query: 1748  G-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKV 1804
             G  S+  +S  PI  K  +++P           I   +       ++ +G   P I++  
Sbjct: 24529 GAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 24588

Query: 1805  EIKQEGKKWKXXXXXXXXXAR-IQKLSINTTY-QFRIYARNEIGT-SLPYTSDDKITIGK 1861
               K+  +  +         A  I K +I     Q+ + A N  G+ S P          K
Sbjct: 24589 GDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV-------K 24641

Query: 1862  TLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
              L  P  P   V V+  TS   +L W+ P  +GGS I++Y++E +     +WT +V    
Sbjct: 24642 VLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWT-VVASEV 24700

Query: 1921  SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
               +   +  + E +E +FRI A N  GV  P ES  V ++    +P PP + LE+  +  
Sbjct: 24701 VTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKS-LEVTNIAK 24759

Query: 1981  NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
             + +   W  P+ DGG+ ++GY +  RD +   W++  K  +  L+  +  L+E+H Y  R
Sbjct: 24760 DSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFR 24819

Query: 2041  IYARNEIGLSEP 2052
             + A N  G+ EP
Sbjct: 24820 VSAENAAGVGEP 24831



 Score =  151 bits (367), Expect = 2e-34
 Identities = 176/756 (23%), Positives = 297/756 (39%), Gaps = 41/756 (5%)

Query: 940  TEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD-VGVIK 998
            +EEG  V L    ++     WY   K +   +  + +Q+              D  G   
Sbjct: 4300 SEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYV 4359

Query: 999  CIV-----KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERD 1052
            C       K   ++ + VVK   P   RK++  EV    +A    EI S       W + 
Sbjct: 4360 CEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKA 4419

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE-LPP 1107
            G  I  + +K       +I  L I  T V D GEY+C   +E    SCTA +TV E  PP
Sbjct: 4420 GREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
              ++R ++     G  A F   +T G  ++   W KDG+ +  S + +++    K  L++
Sbjct: 4479 TFLSRPKSLTTFVGKAAKFICTVT-GTPVIETIWQKDGAALSPSPNWKISDAENKHILEL 4537

Query: 1166 YDCDLDDAGEYSCEVGN----SKCTA-ILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
             +  + D G YSC+  N      C A ++ +++P  +F   L E +    N   +L  ++
Sbjct: 4538 SNLTIQDRGVYSCKASNKFGADICQAELIIIDKP--HFIKEL-EPVQSAINKKVHLECQV 4594

Query: 1221 -PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
              D  + VTW K    +   + + +  + K  TL I      D   Y C   +   ++  
Sbjct: 4595 DEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSC 4654

Query: 1280 KVEV-VEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
               V V  PP  V   +  Y +  G    L    +  P     W  N+K + +    +  
Sbjct: 4655 SATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMY 4714

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
              +  A L I  V+  D+G Y     N+ G       + I + PS        +I   + 
Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTN 4774

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             +   E   TG   I ++  + ++I +    S K    +Q S+  L+    + F +  V 
Sbjct: 4775 ALLQCEVSGTGPFEISWF-KDKKQIRS----SKKYRLFSQKSLVCLEI---FSFNSADVG 4826

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
            E +   A+E  +   +      + PT  K + ++     + + L     G     VTW +
Sbjct: 4827 EYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK 4886

Query: 1518 DGKKLK---TAKATYENRXXXXXX-XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
              + ++     K ++ N                 Y C+A N+ G  +TS    I ++P  
Sbjct: 4887 GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEPAK 4945

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
             I   ++ Q    GD   +   + G P  +  WYK+G  L   K+Y I+ K   + ++  
Sbjct: 4946 IIERAELIQV-TAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFY 5004

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              +   S +YT E SN  G+SS E T  V D+   P
Sbjct: 5005 SAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 5040



 Score =  150 bits (363), Expect = 5e-34
 Identities = 198/893 (22%), Positives = 344/893 (38%), Gaps = 49/893 (5%)

Query: 1191  VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVK 1249
             +E P I+    + + ++V A     L   +       VTW  +K  I++  +   +  V 
Sbjct: 19528 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTW--RKVGIDNVVRKGQVDLVD 19585

Query: 1250  KRT-LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
                 L+I   T DD  +Y+  L++   +    + V V++ P  + D +     K    V+
Sbjct: 19586 TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVS 19645

Query: 1307  LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
                           +IV  +   +   +  + + K  S  +  +   +   +++   N  
Sbjct: 19646 WAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEY 19705

Query: 1367  GHA---DVEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
             G     DV   V   D   +P PP K  + E+  +S  + W  P   G + I  Y+  Y+
Sbjct: 19706 GPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYR 19765

Query: 1421  EID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             E +     W     +      +  LK    Y+FR  A N V +S   E    Y+  KE +
Sbjct: 19766 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA-KE-Q 19823

Query: 1479  IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXX 1534
             +  P +  P + IT +  + + +     G P P   W +   ++ T+   A +  ++   
Sbjct: 19824 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 19882

Query: 1535  XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK--QKHKVGDEWLV 1592
                          Y   A N  G       V +   P       DI           W +
Sbjct: 19883 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHI 19942

Query: 1593  TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                  G      I  +  +    D    + +  KTS  R+ +L       + + A N  G
Sbjct: 19943 PLEDGGSNITNYI-VEKCDVSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFG 20000

Query: 1653  TSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
              S    + K+     +  PS+P+   + + ++++ + + W  P  DGG  +  Y IE+ E
Sbjct: 20001 ISEPLTSPKMVAQFPFGVPSEPKNARVTK-VNKDCIFVAWDRPDSDGGSPIIGYLIERKE 20059

Query: 1708  PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
              ++  W+K  D       Y    L E  EY FR+ A N  G S    S+P    TA  +P
Sbjct: 20060 RNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSP--PSKPTEYVTA-RMP 20116

Query: 1768  SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARI 1826
                        +   +V + W   + +GGS II Y VE  K  G KW           + 
Sbjct: 20117 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 20176

Query: 1827  Q----KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV-SESTSRS 1881
             +     L     YQFR  AR  +  S P    D +TI     PP    +  + S  T ++
Sbjct: 20177 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 20236

Query: 1882  VTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
              T    +    G   P  ++  +   +K     K + +  ++    + ++  KD   + I
Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLCTLELFSVNRKDSGDYTI 20295

Query: 1941  SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
             +AEN+ G    ++S +++L K    P PP A ++I  + S+  M SW  P  DGG+ +  
Sbjct: 20296 TAENSSG----SKSATIKL-KVLDKPGPP-ASVKINKMYSDRAMLSWEPPLEDGGSEITN 20349

Query: 2001  YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
             Y +  R+ ++  W +V    V     ++  L E H Y  RI A N+ G+ +P+
Sbjct: 20350 YIVDKRETSRPNWAQV-SATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 20401



 Score =  150 bits (363), Expect = 5e-34
 Identities = 177/746 (23%), Positives = 296/746 (39%), Gaps = 54/746 (7%)

Query: 1349  KVENTDAGI-YKLRL--ENNCGHADVEMN---VTILDKPSPPGKPNILEIDSSSINICWD 1402
             K +N + GI Y+ R+  EN  G      N       D   PPG P  + +  + I + W 
Sbjct: 24410 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 24469

Query: 1403  EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
             +P   G S I  Y+VE +++    W+  S  N+ +TQ ++  L  +  Y FR  A N   
Sbjct: 24470 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 24529

Query: 1461  -ISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
              IS  S++T       E ++   +++   ++ I     E   L     G P P + W R 
Sbjct: 24530 AISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRG 24589

Query: 1519  GKKLK-TAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
              K+++ +A+   +N   +               Y   A N  G       V +  +P   
Sbjct: 24590 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPP 24649

Query: 1575  ISNEDIK--QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIR 1631
                  +      K    W       G    ++  Y    +  +   + +   E  T+ ++
Sbjct: 24650 EGPVQVTGVTSEKCSLTWSPPLQDGG---SDISHYVVEKRETSRLAWTVVASEVVTNSLK 24706

Query: 1632  IKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEW 1687
             + +L   +   + I A N  G    +E    +   P    GP   + +  I+++S+T+ W
Sbjct: 24707 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 24766

Query: 1688  KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
               P  DGG E+  Y +EK +    RWIK            +  L E+ EY FRV A+N  
Sbjct: 24767 NRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAA 24826

Query: 1748  GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN--ESVYITWFPSEKNGGSPIIDYKVE 1805
             G  E   S   V   A D             +D    S+ + W     +GGS I+ Y VE
Sbjct: 24827 GVGEP--SPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 24884

Query: 1806  I-KQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIG----TSLPYT--SDD 1855
             I K + ++W+              I KL+ +  Y+ R+ A N++G    TS+P T   +D
Sbjct: 24885 ICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPED 24944

Query: 1856  KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
             K+   +        +  VV    S  + + +       G P     I +   +G+   K+
Sbjct: 24945 KLEAPELDLDSELRKGIVVRAGGSARIHIPFK------GRPTPE--ITWSREEGEFTDKV 24996

Query: 1916  -VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
              +  G +  +  I+N    D   + +  EN+ G    ++S  V + K    P PP   L 
Sbjct: 24997 QIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTV-KVLDTPGPPQN-LA 25050

Query: 1975  IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
             ++ V  +     W  P  DGGA +  Y I  R+ T+  +  V      T  F + +L+E 
Sbjct: 25051 VKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKT-SFKVENLTEG 25109

Query: 2035  HTYMIRIYARNEIGLSEPLESDEPFK 2060
               Y  R+ A NE G+  P+E+ +  K
Sbjct: 25110 AIYYFRVMAENEFGVGVPVETVDAVK 25135



 Score =  149 bits (362), Expect = 6e-34
 Identities = 178/802 (22%), Positives = 301/802 (37%), Gaps = 60/802 (7%)

Query: 1358  YKLRLENNCGHADVE--MNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
             +++  EN+ G +        T+   P  PPG P+ +++   +I + W+ P   G S I+ 
Sbjct: 28756 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 28815

Query: 1415  YVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471
             Y +E ++     W+  +  ++++ Q ++  L     Y FR  A N V  IS  S+++   
Sbjct: 28816 YSIEKRQ-GNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGI- 28873

Query: 1472  KVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG----KKLKT 1524
              ++   +   P VE   +    +  +  E + +  +  G P P+VTW++DG    K++  
Sbjct: 28874 -IMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 28932

Query: 1525  AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584
                                    Y   A N  G  +    V +Q  P   +    I+  +
Sbjct: 28933 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVG--PIRFTN 28990

Query: 1585  KVGDE---WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
               G++   W    + +G  P   I +    K E  +      ++K        +K  + +
Sbjct: 28991 ITGEKMTLWWDAPLNDGCAP---ITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGN 29047

Query: 1642  KY--TIEASNTAGT----SSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
             +Y   + A N  G      S  V  ++ Y  P  P  P     I+  S+T+ W  P  DG
Sbjct: 29048 EYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPE-PSNITGNSITLTWARPESDG 29106

Query: 1695  GLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEAL 1753
             G E+ +Y +E+ E  + RW+KV       ET + +  L E  EY F V+A+N  G   A 
Sbjct: 29107 GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPAS 29166

Query: 1754  ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKK 1812
                 ++       P               +V + W     +GG  II Y +E+ K +   
Sbjct: 29167 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 29226

Query: 1813  WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ-- 1868
             W           R  +  L     Y+FR+ A N  G          I     LT P    
Sbjct: 29227 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDI 29286

Query: 1869  PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
               NF  +       +++     +  G P T   +  K     S    +    S     +E
Sbjct: 29287 DANFKQTHVVRAGASIRLF--IAYQGRP-TPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 29343

Query: 1929  NIKEKDEIIFRISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSW 1987
             N    D   + ++ EN  G      S+S+    K    P PP  P+  + V        W
Sbjct: 29344 NCNRNDAGKYTLTVENNSG------SKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMW 29396

Query: 1988  GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
               P  DGGA +  Y +  R+ ++  W  + +     + F + DL+E   Y  R+ A NE 
Sbjct: 29397 DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEY 29455

Query: 2048  GLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDADIRSY 2106
             G+ EP E  EP          A E+P     +             WL+ +H+  + I  Y
Sbjct: 29456 GVGEPYEMPEPIV--------ATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGY 29507

Query: 2107  ARGSLLRRDEYFFRIWHYAKQL 2128
                   +  +++    H  KQL
Sbjct: 29508 LLEMRQKGSDFWVEAGH-TKQL 29528



 Score =  147 bits (355), Expect = 4e-33
 Identities = 117/440 (26%), Positives = 189/440 (42%), Gaps = 28/440 (6%)

Query: 1631  RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEGPVIMREISRESVT 1684
             ++  L   H  ++ I A N AG S+   T   Y       KP  P  P ++ + SR S++
Sbjct: 22642 KVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVL-DTSRSSIS 22700

Query: 1685  IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
             I W  P+ DGG E+T Y +E   P+ + W I          +Y I  L EN EY  R+ A
Sbjct: 22701 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 22760

Query: 1744  QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIID 1801
              N  G  E AL       +  +  P           +   +   +  F   K   +P + 
Sbjct: 22761 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVK 22820

Query: 1802  YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             +  +  +   K             +  ++   + ++ +   N  G+   + +       +
Sbjct: 22821 WARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNV------R 22874

Query: 1862  TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
              L  P  P++  V E T  SVTL W  P  +GGS I NYI+E +    K+++   TV  +
Sbjct: 22875 VLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS---TVATN 22931

Query: 1922  VHEHC--IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978
              H+    ++ ++E     FR+ AEN  G+ LP E ++SV+  +    P PP   + +  V
Sbjct: 22932 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PLPP-GKITLMDV 22987

Query: 1979  GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
               N V  SW  PE DGG+ +LGY + ++      W     V V   +  I  L +   Y 
Sbjct: 22988 TRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVT--EATITGLIQGEEYS 23045

Query: 2039  IRIYARNEIGLSEPLESDEP 2058
              R+ A+NE G+S+P +   P
Sbjct: 23046 FRVSAQNEKGISDPRQLSVP 23065



 Score =  140 bits (338), Expect = 5e-31
 Identities = 102/345 (29%), Positives = 149/345 (43%), Gaps = 14/345 (4%)

Query: 1739  FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
             + + A N  G ++A  +  IV+   LD P           I  ESV + W P + +GGS 
Sbjct: 27474 YEITAANSSGTTKAFIN--IVV---LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQ 27528

Query: 1799  IIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
             + +Y + +K+E     W +          ++ KL+    YQFRI A N  G S  +    
Sbjct: 27529 VTNY-ILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGIS-DHIDSA 27586

Query: 1856  KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
              +T+    T P  P    V+  T  S+T+ W EP SNGGS +  Y +E K      W K 
Sbjct: 27587 CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 27646

Query: 1916  VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
               +        +  I       FR+ AEN  GV  P+      L   A     P   + I
Sbjct: 27647 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC---EPPRNVRI 27703

Query: 1976  RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
               +  N V  SW  P +DGG+ + GY +  RD+    W +    +V   +F I  L++N 
Sbjct: 27704 TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNS 27763

Query: 2036  TYMIRIYARNEIG-LSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
              Y  R++ARN +G +S P E   P   I   G    + P E TEV
Sbjct: 27764 QYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEV 27808



 Score =  137 bits (331), Expect = 4e-30
 Identities = 196/790 (24%), Positives = 319/790 (40%), Gaps = 70/790 (8%)

Query: 1214  AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271
             A L+ +I    L D+ WY+    +  + K+ + SD +  TL +    ++D+  YTC+   
Sbjct: 31477 AQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 31536

Query: 1272  ---DAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
                + ++++KL ++   +F P     E+ Y    GS + L V Y   P P   W    K+
Sbjct: 31537 EVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWFHGQKL 31595

Query: 1328  IKKCKHTKPSIDSKSASLTIKKVE-NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             ++  ++           L +K V+  T AG YK++L N  G  D  ++V I DKP  P  
Sbjct: 31596 LQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG 31655

Query: 1387  PNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKN-ITKTQTSIQNL 1443
             P ++E +  +S  I W  P + G S I  YVVE  E  +  EW  V + I+ T   I NL
Sbjct: 31656 PIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNL 31715

Query: 1444  KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
               N+ Y FR  A N   ISD  E +    VI ++  + P    P K   T   +D   +C
Sbjct: 31716 TENAGYYFRVSAQNTFGISDPLEVSSV--VIIKSPFEKPGA--PGKPTITAVTKD---SC 31768

Query: 1504  IFGGVPQ-----PKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIA 1552
             +    P       K+  Y    R+ K+ K    T E                 Y  +   
Sbjct: 31769 VVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKC 31828

Query: 1553  FNDHGEVETSCV-VGIQQKPVITISNEDIKQKHK---VGDEWLVTAV--IEGIPPPEVIW 1606
              N  GE E S +   I  K  + I     K++ +   V  +   T V  + G P P V W
Sbjct: 31829 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 31888

Query: 1607  YKNGNKLEND-KEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSS------VEV 1658
             Y+ G ++  D  +Y I   K     + I  +    ++ Y + A+N  G+ S      VEV
Sbjct: 31889 YRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 31948

Query: 1659  TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
               K++  P   EG   +  +  E V+I  K P       +  +   +   DNN   +V  
Sbjct: 31949 PAKIH-LPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITWQKGQDLIDNNGHYQVI- 32004

Query: 1719  VDRDVETYCIQKLNENCEYMFRVI-AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
             V R   +       E  +  F V+ A+N  G    ++ + + +  A DVP          
Sbjct: 32005 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFG----IDQKTVELDVA-DVPD-PPRGVKVS 32058

Query: 1778  XIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQ 1836
              +  +SV +TW     +GGS I +Y VE      ++W            +  L   T+YQ
Sbjct: 32059 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQ 32118

Query: 1837  FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             FR+ A N+ G S P    +      T+T   + R     E    +  +  T+   +    
Sbjct: 32119 FRVIAENKFGLSKPSEPSE-----PTITKEDKTRAMNYDEEVDETREVSMTKASHSSTKE 32173

Query: 1897  I-TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             +   Y+I     +G+         G VH  C+E   +K  +   +  + T  V +  E  
Sbjct: 32174 LYEKYMIAEDLGRGEF--------GIVH-RCVETSSKKTYMAKFVKVKGTDQVLVKKEIS 32224

Query: 1956  SVRLEKHATV 1965
              + + +H  +
Sbjct: 32225 ILNIARHRNI 32234



 Score =  134 bits (323), Expect = 3e-29
 Identities = 205/920 (22%), Positives = 361/920 (39%), Gaps = 86/920 (9%)

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            KKPK     E + +  E  +     P + W  K  EI P +   +  E  +H     L +
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK----LML 2853

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
             N+     G YT V    E +A L +         E   + + +K++ V + ++     +
Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFV---------ETLHITKTMKNIEVPETKTASFECE 2904

Query: 758  VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            V     P++ W KN   ++          G  H + I+     +D   YT    N +   
Sbjct: 2905 VSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS-TEDSAEYTFVCGNDQ--- 2959

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
              SA +TV         P +  +  ++I  +EK TI     V    + S  W +N   I 
Sbjct: 2960 -VSATLTVT--------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIK 3009

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             ++            L I NV    D+ DY  VA    GK++  A + ++   + F KH+
Sbjct: 3010 STDKCQMRTKKLTHSLNIRNVHFG-DAADYTFVA----GKATSTATLYVEARHIEFRKHI 3064

Query: 935  QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
             K  +  E K  + EC+ S   ++ +W  + +E+   D  +I +E              D
Sbjct: 3065 -KDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123

Query: 994  VGVIKCIVKDQETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVVWERD 1052
             G    +V     ST  +  E     IR ++ + +V EK  A++E E+N +  D  W +D
Sbjct: 3124 AGKYT-VVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKD 3182

Query: 1053 GEIIK---PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPE 1108
            G  I     +++KY  E+R H  +++I  T   D GEY+ +  R+ S          PP+
Sbjct: 3183 GIEINFQVQERHKYVVERRIH--RMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQ 3240

Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
            ++  LQ   V  G  A F   ++ +    + W+K+   +      +   DG++  L + +
Sbjct: 3241 VLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3300

Query: 1168 CDLDDAGEYSCEVGN----SKCTAILTVEEPSI-NFTLRLPEF---ILVPANTD------ 1213
               +DA  Y+CE  N    +  +A L+VE P + +    +P +   I+ P          
Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ 3360

Query: 1214 -AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             A     +    L V+WY K   I+ +  F +        L I +   +D+  YT V  +
Sbjct: 3361 PARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3420

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI-IKKC 1331
            A         +    P+ + +E   RI++  ++ +     +F    +E + ++++ + K 
Sbjct: 3421 AVGQVSSTANLSLEAPESILHE---RIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKI 3477

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAG-IYKLRLEN-NCGHADV-EMNVTILDKPSPPGK-- 1386
              T   +       T    E    G I+   + N +    DV  ++VT++  P P  +  
Sbjct: 3478 NETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWF 3537

Query: 1387 -PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
               +L   S+     +D  +   +S II +     E + T  ++  +  KT  S   LK 
Sbjct: 3538 FNGVLLTPSADYKFVFDGDD---HSLIILFTKLEDEGEYT-CMASNDYGKTICSAY-LKI 3592

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
            NS          E  ++ + E        K      P   K LK I              
Sbjct: 3593 NSKGEGHKDTETESAVAKSLE--------KLGGPCPPHFLKELKPIRCAQGLPAIFEYTV 3644

Query: 1506 GGVPQPKVTWYRDGKKLKTA 1525
             G P P VTW+++ K+L T+
Sbjct: 3645 VGEPAPTVTWFKENKQLCTS 3664



 Score =  133 bits (321), Expect = 6e-29
 Identities = 118/411 (28%), Positives = 171/411 (41%), Gaps = 31/411 (7%)

Query: 1666  PSKPEGPVIMREIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             P KP GP    E+S   ++S+ + W  P+DDGG E+  Y +EK + +  RW K       
Sbjct: 25825 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 25884

Query: 1723  VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXID 1780
                  +  L E   Y FRV A+N  G  E   SEP V   A D   P             
Sbjct: 25885 DLRLRVTGLTEGHSYEFRVAAENAAGVGEP--SEPSVFYRACDALYPPGPPSNPKVTDTS 25942

Query: 1781  NESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR---IQKLSINTTYQ 1836
               SV + W     +GG+P+  Y VE+K+    +W           +   + KL  NT Y 
Sbjct: 25943 RSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 26002

Query: 1837  FRIYARNEIGTSLPYTSDDKITIGKTLTPP-----SQPRNFVVSESTSRSVTLKWTEPES 1891
             FRI A N  G   P T    +   + + PP     +  R  VV  +   S TL+      
Sbjct: 26003 FRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA---SATLRLFVTIK 26059

Query: 1892  NGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
                 P     ++++  +G    +  + V  S     I+N+   D   + ++ EN  G   
Sbjct: 26060 GRPEP----EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK- 26114

Query: 1951  PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
              T   +VR+      PS P   L IR V  + V  SW  P  DGGA +  Y +  R+ T+
Sbjct: 26115 -TAFVNVRV---LDSPSAP-VNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 26169

Query: 2011  TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
               +  +      T  F I +L E  +Y  R+ A NE G+  P E+ EP KV
Sbjct: 26170 KAYATITNNCTKT-TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 26219



 Score =  130 bits (313), Expect = 5e-28
 Identities = 142/602 (23%), Positives = 246/602 (40%), Gaps = 42/602 (6%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E    P+F + L P    +G  VQ  C V+G    +I W +    IKPS D   +    
Sbjct: 9267 KEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPS-DRCSFSFAS 9325

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
              A L +R+V   D+G + C A N AG  S TT+           S++T+          
Sbjct: 9326 GTAVLELRDVAKADSGDYVCKASNVAG--SDTTK-----------SKVTIKDKPAVAPAT 9372

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
              A + +G    F  +P++  V E +      ++   P P++ W  KG+    ++   V 
Sbjct: 9373 KKAAV-DG-RLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT-KGKWRQLNQGGRVF 9429

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
            I        + L+I +  K   G Y  VA N  GE    + L++   +K+  ++   L++
Sbjct: 9430 IHQKGDE--AKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQ-EKIEGDLRA 9486

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKP----KKVK 798
            M+ +    ++            +   KN  P +     +  G T    +L+     K+ +
Sbjct: 9487 MLKK--TPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQ 9544

Query: 799  DEGVYTLKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIKLV 853
            +E  + L+ E  E       E   +++  +      EP   I   +  TV K+   +  +
Sbjct: 9545 EEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEI 9604

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                  P   ++WY+  E + PS+    + DG+   L + N   + D G+Y+ V      
Sbjct: 9605 DIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLK-DQGNYRLVC----- 9658

Query: 914  KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDH 972
               H A   + V +  + +HLQ     +EG+T  + CQ S   V ++W+ N + +     
Sbjct: 9659 -GPHIASAKLTVIEPAWERHLQ-DVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGR 9716

Query: 973  REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKD 1032
             +   E +            D G   C  +D ETS  L ++    +F +++Q+  V E  
Sbjct: 9717 HKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQ 9776

Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
             A  E E++ + A V W + G     +  KY+F   G    + I N +  DEG YS I R
Sbjct: 9777 SATFECEVSFDDAIVTWYK-GPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIAR 9835

Query: 1093 DE 1094
             E
Sbjct: 9836 LE 9837



 Score =  129 bits (311), Expect = 9e-28
 Identities = 112/445 (25%), Positives = 188/445 (42%), Gaps = 29/445 (6%)

Query: 1630  IRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--VYDKPSKPEGPVI---MREISRESVT 1684
             ++++ L   H  ++ ++A N  G     +  +  V   P +P GP     + + ++ S+T
Sbjct: 19382 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSIT 19441

Query: 1685  IEWKPPLDDGGLELTKYAIEKH------EPDNNRWIKVADVDRDV-ETYCIQKLNENCEY 1737
             + W  P+ DGG  +  Y +E         PD   W +     + V + + +  L+EN EY
Sbjct: 19442 LGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCNAAAQLVRKEFTVTSLDENQEY 19500

Query: 1738  MFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXX-IDNESVYITWFPSEKNG 1795
              FRV AQN VG     E  E I  K  L+ P            I      I  F   +  
Sbjct: 19501 EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR 19560

Query: 1796  GSPIIDY-KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
              +P + + KV I    +K +           I   + + + ++ +   N  G    + + 
Sbjct: 19561 PAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNV 19620

Query: 1855  DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
                   + L  P    +  VS+ T  S  + W  PE++GGS +T+YI+E +    K+W+ 
Sbjct: 19621 ------RVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 19674

Query: 1915  IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPL 1973
             +         H + N+   +E  FR++A N  G  +PT+  + V      + P PP   L
Sbjct: 19675 VTPEVKKTSFH-VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPP-RKL 19732

Query: 1974  EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK--TMWMEVGKVDVNTLKFNIRDL 2031
             E+  +  N    +W  P  DGGA + GY  + R+  +    W E     V  L   +  L
Sbjct: 19733 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSV--VKDLSLVVTGL 19790

Query: 2032  SENHTYMIRIYARNEIGLSEPLESD 2056
              E   Y  R+ ARN +G+S P E++
Sbjct: 19791 KEGKKYKFRVAARNAVGVSLPREAE 19815



 Score =  125 bits (302), Expect = 1e-26
 Identities = 86/303 (28%), Positives = 131/303 (43%), Gaps = 7/303 (2%)

Query: 1754  ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812
             +S PI +K  LD P           +  E  Y+ W P  ++GG+ I  Y +E ++  +  
Sbjct: 25717 KSIPITVKV-LDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 25775

Query: 1813  W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
             W +          ++ KL     Y FR+ A N+ G   P  S   +T      PP  P  
Sbjct: 25776 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP-VTACNPYKPPGPPST 25834

Query: 1872  FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
               VS  T  S+ + W  P  +GG+ I  YI+E +  +G  WTK      +     +  + 
Sbjct: 25835 PEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 25894

Query: 1932  EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
             E     FR++AEN  GV  P+E S   R       P PP+ P ++     + V  +W  P
Sbjct: 25895 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP-KVTDTSRSSVSLAWSKP 25953

Query: 1991  EWDGGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
              +DGGAP+ GY + +++     W        +   +F +  L EN  Y  RI A N  G+
Sbjct: 25954 IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGV 26013

Query: 2050  SEP 2052
              EP
Sbjct: 26014 GEP 26016



 Score =  124 bits (300), Expect = 2e-26
 Identities = 90/303 (29%), Positives = 135/303 (44%), Gaps = 11/303 (3%)

Query: 1757  PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815
             PI + T L  PS          I  +SV ++W   E NGG  I  Y +E ++  +  WK 
Sbjct: 28575 PITVIT-LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKM 28633

Query: 1816  XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFV 1873
                       ++  L  +  YQFR+ A N  G S P  S   I + K     P  P   V
Sbjct: 28634 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS--IIVAKHQFRIPGPPGKPV 28691

Query: 1874  VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
             +   TS  ++L W  P  +GGS +T + +E K      W K+ T   S  E+    + E 
Sbjct: 28692 IYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEG 28751

Query: 1934  DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
              +  FR+ AEN+ G+S P++     L    +   PP  P  I +    I +  W  P  D
Sbjct: 28752 LDYQFRVYAENSAGLSSPSDPSKFTLA--VSPVDPPGTPDYIDVTRETITL-KWNPPLRD 28808

Query: 1994  GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEP 2052
             GG+ ++GY+I  R   +  W+     DV+  ++ +  LS    Y  RI ARN +G +S P
Sbjct: 28809 GGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPP 28867

Query: 2053  LES 2055
              +S
Sbjct: 28868 SQS 28870



 Score =  124 bits (299), Expect = 3e-26
 Identities = 159/709 (22%), Positives = 282/709 (39%), Gaps = 39/709 (5%)

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
            VK QE    L+ KE  P     L D   +E D+  L   I +   +V W  + +++ P  
Sbjct: 4274 VKIQEAEGGLI-KEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLV-PSD 4330

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHD-EGEYSC-ILRDESCTA---EVTVVELPPEIITR-LQ 1114
             K+   +  +   L I   +  D +GEY C  L D   TA   ++TVV+    +I R ++
Sbjct: 4331 EKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIE 4390

Query: 1115 NQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
              +V  G+ A F  E+    +   +WFK G EI  S+   +        L+I    + D 
Sbjct: 4391 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 4450

Query: 1174 GEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLDVT 1228
            GEY+C    E G+  CTA LTV E      L  P+ +       A ++        ++  
Sbjct: 4451 GEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETI 4510

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEF 1286
            W K  + +  +  + +     K  L +   T  D+  Y+C   +       + E  +++ 
Sbjct: 4511 WQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 4570

Query: 1287 PPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            P  I + E  +  I +   +   VD     +    W  + + +   K  K   + K A+L
Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDEDR--KVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDSSSINI-CWD 1402
             I   +  D+G Y     N  G +     VT+ + PS   K  P+ L +   S  + C  
Sbjct: 4629 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKL 4688

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            +       T      E  E +T     V +  +    I ++K   S  +   AVN  D+ 
Sbjct: 4689 KGSPVIQVTWFKNNKELSESNTVRMYFVNS--EAILDITDVKVEDSGSYSCEAVN--DVG 4744

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
              S +TE   VIKE     P+  K L+        +  L C   G    +++W++D K++
Sbjct: 4745 SDSCSTEI--VIKEP----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI 4798

Query: 1523 KTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
            +++K     + ++                Y+C+  N+ G+        +++ P      +
Sbjct: 4799 RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVD 4858

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            D+      G    + A + G  P  V W K    +  D +  ++     +V+ I +++ S
Sbjct: 4859 DLIALG--GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQIS 4916

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
               KYT  A N AG+ +    L V +     E   +++  + +  T+E+
Sbjct: 4917 FGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 4965



 Score =  124 bits (298), Expect = 4e-26
 Identities = 123/454 (27%), Positives = 188/454 (41%), Gaps = 34/454 (7%)

Query: 1627  TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             T+   ++ L      ++ ++A N  G S   + L V  +  +   P I   +S    TI+
Sbjct: 16278 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP-PTIKLRLSVRGDTIK 16336

Query: 1687  WKP------PLDDGGLELTKYAIEKHE-----PDNNRWIKVADVDR-DVET-YCIQKLNE 1733
              K       P D  GL + K    K+E     P +   I   +V R + +T   I K   
Sbjct: 16337 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 16396

Query: 1734  NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
               +  + V A N +G      +  + +    D PS          I  ES Y+TW     
Sbjct: 16397 EDKGTYTVTASNRLG--SVFRNVHVEV---YDRPSPPRNLAVTD-IKAESCYLTWDAPLD 16450

Query: 1794  NGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSL 1849
             NGGS I  Y ++ +   +K   W+            I KL  N  Y+FR+ A N+ G S 
Sbjct: 16451 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISD 16510

Query: 1850  PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
                SD K+ I      P  P    V   T  S+ + WT P  NGGSPIT Y +E +    
Sbjct: 16511 ECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGS 16569

Query: 1910  KSWTK-----IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
               W++     I  VG    E  +  + E  +  FR  A N  G+  P+E     +     
Sbjct: 16570 PYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPI 16629

Query: 1965  VP-SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD--V 2021
              P  PP+ P E++    + +   W  P  DGG+P+ GY + +++   T W  V + D  +
Sbjct: 16630 FPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLI 16688

Query: 2022  NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              T +  + +L E   Y  R+ A NE G SEP ++
Sbjct: 16689 TTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT 16722



 Score =  123 bits (297), Expect = 5e-26
 Identities = 83/293 (28%), Positives = 131/293 (44%), Gaps = 15/293 (5%)

Query: 1779  IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXX-XARIQKLSINTTY 1835
             + ++   + W P E +GG  I +Y +E K E K+  W             + +L     Y
Sbjct: 19235 VSSDRCTVCWDPPEDDGGCEIQNYILE-KCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 19293

Query: 1836  QFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
              FR+ A N+IGT  P  ++ K  I KT    P +P    V++ +   +T+ W  PE +GG
Sbjct: 19294 IFRVRAENKIGTGPP--TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGG 19351

Query: 1895  SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-E 1953
               IT Y +E K      W  +           ++N+    E  FR+ AEN +G+  P+  
Sbjct: 19352 KSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLP 19411

Query: 1954  SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
             S+ V  +     P PPT    +     +I +  WG P +DGGAP++GY + +R       
Sbjct: 19412 SRPVVAKDPIEPPGPPTNFRVVDTTKHSITL-GWGKPVYDGGAPIIGYVVEMRPKIADAS 19470

Query: 2014  MEVGKVDVNTL------KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
              + G    N        +F +  L EN  Y  R+ A+N++G+  P E  E  K
Sbjct: 19471 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 19523



 Score =  123 bits (296), Expect = 6e-26
 Identities = 145/607 (23%), Positives = 241/607 (39%), Gaps = 44/607 (7%)

Query: 1499  IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXX----XXXXXYKCIAF 1553
             + L  ++ G P P +TW+   K L+ ++  T EN                    YK    
Sbjct: 31573 LRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 31632

Query: 1554  NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV--IWYKNG- 1610
             N  G V+    V IQ KP        I+   K       +AVI   PP +    W  N  
Sbjct: 31633 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN------SAVISWKPPADDGGSWITNYV 31686

Query: 1611  -NKLENDK--EYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTL 1660
               K E  +  E+ + +     +  RI  L  +    + + A NT G       SSV +  
Sbjct: 31687 VEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIK 31746

Query: 1661  KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
               ++KP  P  P I   ++++S  + WKPP  DGG ++  Y +EK E   N+WI V   +
Sbjct: 31747 SPFEKPGAPGKPTITA-VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE 31805

Query: 1721  RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXI 1779
                  + ++ L E  EY FRV  +N  G SE  E SEPI  K+ + + +           
Sbjct: 31806 IRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLN 31865

Query: 1780  DNESVYITWFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARI-QKLSINTTY 1835
                    T          PI+ +     EI  +G K++           I   ++ +   
Sbjct: 31866 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 31925

Query: 1836  QFRIYARNEIGTSLPYTSDDKITI-GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
              +++ A N+ G S+  T+  ++ +  K   P +      V       V++K   P S   
Sbjct: 31926 VYQVRATNQ-GGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKI--PFSGKP 31982

Query: 1895  SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
              P+  +      +      +++             ++ KD   + + A+N  G+    + 
Sbjct: 31983 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGI----DQ 32038

Query: 1955  QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
             ++V L+  A VP PP   +++  V  + V  +W  P  DGG+ +  Y +     T   W+
Sbjct: 32039 KTVELDV-ADVPDPPRG-VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWL 32096

Query: 2015  EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP--FKVIPGEGSHADEE 2072
              VG+      ++ + +L    +Y  R+ A N+ GLS+P E  EP   K       + DEE
Sbjct: 32097 RVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEE 32154

Query: 2073  PGEQTEV 2079
               E  EV
Sbjct: 32155 VDETREV 32161



 Score =  120 bits (288), Expect = 6e-25
 Identities = 88/313 (28%), Positives = 139/313 (44%), Gaps = 10/313 (3%)

Query: 1764  LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822
             LD P           +  E   + W P  ++GGS II+Y VE ++  +  W         
Sbjct: 23561 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 23620

Query: 1823  XA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
              + ++ KL     Y FRI A N+ G   P  S+  +     + P + P+   V+  T  S
Sbjct: 23621 LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDA-PKAPEVTTVTKDS 23679

Query: 1882  VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRI 1940
             + + W  P S+GGS I  Y++E +  +G  WT+    + G +    +  + E  +  FR+
Sbjct: 23680 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLR-VTGLIENHDYEFRV 23738

Query: 1941  SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
             SAEN  G+S P+   + +        P PP  P  I +  S++ + SW  P +DGG  + 
Sbjct: 23739 SAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFL-SWSKPIYDGGCEIQ 23797

Query: 2000  GYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             GY +   DV+   W M      +N     +  L E H Y  RI A N+ G+ E   +D P
Sbjct: 23798 GYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGE--HADVP 23855

Query: 2059  FKVIPGEGSHADE 2071
               +I  E   A +
Sbjct: 23856 GPIIVEEKLEAPD 23868



 Score =  115 bits (276), Expect = 2e-23
 Identities = 109/456 (23%), Positives = 179/456 (39%), Gaps = 28/456 (6%)

Query: 1618  EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
             EY++       V  +KE K+    K+ + A N  G S       VY+   +   P I+  
Sbjct: 19776 EYSVVKDLSLVVTGLKEGKKY---KFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP 19832

Query: 1678  ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
                E +TI+    L      +  +   K  P   +W K  D         + K + +   
Sbjct: 19833 ---EQITIKAGKKL-----RIEAHVYGKPHP-TCKWKKGEDEVVTSSHLAVHKADSSSIL 19883

Query: 1738  MFRVIAQNPVGF-------SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
             + + + +   G+       S   +++ I +   +D P           ID ++  ++W  
Sbjct: 19884 IIKDVTRKDSGYYSLTAENSSGTDTQKIKV-VVMDAPGPPQPPFDISDIDADACSLSWHI 19942

Query: 1791  SEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTS 1848
               ++GGS I +Y VE     +  W          + R+ KL     Y FR+ A N  G S
Sbjct: 19943 PLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGIS 20002

Query: 1849  LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
              P TS  K+        PS+P+N  V++     + + W  P+S+GGSPI  Y+IE K   
Sbjct: 20003 EPLTSP-KMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERN 20061

Query: 1909  GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
                W K         E+    + E  E  FRI A N  G S P++         A +P  
Sbjct: 20062 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT---ARMPVD 20118

Query: 1969  PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV--DVNTLKF 2026
             P    E+  V  + V   W  P+ DGG+ ++GY +    +    W+        +   ++
Sbjct: 20119 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 20178

Query: 2027  NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
                 L E   Y  R  AR  + +S P E  +P  ++
Sbjct: 20179 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 20214



 Score =  107 bits (258), Expect = 3e-21
 Identities = 105/448 (23%), Positives = 177/448 (39%), Gaps = 41/448 (9%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  V  L+     +G +V  EC + GYP P +TW+R+   I+ S DFQ+ +    +A L+
Sbjct: 943  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLM 1001

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXXXXXXXXAD 627
            IRE F ED+G FTC A N AG  S++  L V+         + +T              D
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061

Query: 628  IL--------------EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
            ++              E   P F  KP  Q + EG  ++  C++   P+P + W   G  
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121

Query: 674  IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
            +       V+          V+ +T       G YT+V  N+ GE S    L     E +
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFAD--DAGEYTIVVRNKHGETSASASL---LEEAD 1176

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
               +++  + M+ +   +  +    VG   P   + +  K  +             T++ 
Sbjct: 1177 YELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVV 1236

Query: 794  PKKVKDEGVYTLKAENS--EGIAETSAVITVEEPTEENAEPPLFIN-------------R 838
               V+D+  +    E    + I       T+EE  EE+ E  + ++             R
Sbjct: 1237 RTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLR 1296

Query: 839  FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVD 896
             +   + E   +    +++  P+P I WY++ + I   E    +F  DG    L I  V 
Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1355

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTID 924
             E D G Y   ASN  G +    ++ ++
Sbjct: 1356 PE-DEGIYTAFASNIKGNAICSGKLYVE 1382



 Score =  107 bits (258), Expect = 3e-21
 Identities = 77/283 (27%), Positives = 123/283 (43%), Gaps = 11/283 (3%)

Query: 1779  IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXA-RIQKLSINTT 1834
             I   SV   W P   +GGS II+Y +E K + K   +W             + KL     
Sbjct: 15740 IRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKE 15799

Query: 1835  YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
             Y FR+ A N  G   P  S   +       PP  P   +V + TS S+ +KW EP+ NG 
Sbjct: 15800 YLFRVRAENRFGPGPPCVSKPLVA-KDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG- 15857

Query: 1895  SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
             SPI  Y +E + V    W+++     +  +  ++ + E    +FR+ AEN  G   P + 
Sbjct: 15858 SPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAG---PGKF 15914

Query: 1955  QSVRLEKHATVP-SPPTAPL-EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
                   K A  P SPP  P+  +    S  +   W  P ++GG  ++GY +  + V    
Sbjct: 15915 SPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 15974

Query: 2013  WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
             W    +  +   ++ ++++ E   Y +R+ A N  G   P E+
Sbjct: 15975 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGET 16017



 Score =  107 bits (258), Expect = 3e-21
 Identities = 80/287 (27%), Positives = 127/287 (44%), Gaps = 12/287 (4%)

Query: 1779  IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQ 1836
             +  ES  ++W   +  GG+ I +Y VE ++ G   W+           ++  L+    Y 
Sbjct: 29680 VSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYS 29739

Query: 1837  FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             FR+ + N  G S P  S   I       PPS P    V   ++ +++++W EP  +GGS 
Sbjct: 29740 FRVSSENRFGVSKPLESAP-IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSK 29798

Query: 1897  ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955
             I  Y +E K      W K   V      + +  + E  E  FR  A N  GVS  +E S+
Sbjct: 29799 IIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR 29858

Query: 1956  SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT---M 2012
              +  +     P  P    E+  V  + V   W  P +DGG+ ++GY I  + V++     
Sbjct: 29859 PIMAQNPVDAPGRP----EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 29914

Query: 2013  WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEP 2058
             W++     V+   F +  LSE  TY  R+ A+N  G +S+  ES  P
Sbjct: 29915 WLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGP 29961



 Score =  107 bits (256), Expect = 4e-21
 Identities = 116/515 (22%), Positives = 208/515 (40%), Gaps = 31/515 (6%)

Query: 1554  NDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY--KN 1609
             NDHG  +  C V +     P I    EDI+ K  V  +W    + +G    E+I Y  + 
Sbjct: 15712 NDHGIAKAPCTVSVLDTPGPPINFVFEDIR-KTSVLCKW-EPPLDDG--GSEIINYTLEK 15767

Query: 1610  GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKVY 1663
              +K + D E+ + T   +     + +L       + + A N  G      S   V    +
Sbjct: 15768 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF 15827

Query: 1664  DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
               P  P+ P++  +++  S+ ++W  P D+G   +  Y +EK E ++  W +V     + 
Sbjct: 15828 GPPDAPDKPIV-EDVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNA 15885

Query: 1724  ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNE 1782
                 +  L E   Y+FRV A+N  G  +   S P   KTA D +              + 
Sbjct: 15886 LKANVDGLLEGLTYVFRVCAENAAGPGKF--SPPSDPKTAHDPISPPGPPIPRVTDTSST 15943

Query: 1783  SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRI 1839
             ++ + W P   NGG  I+ Y V+ +  G  +W           +  ++++     Y+ R+
Sbjct: 15944 TIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRV 16003

Query: 1840  YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
              A N  G   P      +T+ +   PP+   +  V              P    G P+  
Sbjct: 16004 SAVNAAGEG-PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPT 16062

Query: 1900  YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
              +   +  +      ++   G+  E  I++   KD   + I+A N+ G    ++  + R+
Sbjct: 16063 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG----SKFAAARV 16118

Query: 1960  EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
             E    VP  P   L+  +    + + +W  PE DGG+ + G+ I  +D     W +   +
Sbjct: 16119 EVF-DVPG-PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ--PI 16174

Query: 2020  DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
             +    K +I  L E   Y  R+ A+N+ G   P+E
Sbjct: 16175 ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVE 16209



 Score =  104 bits (249), Expect = 3e-20
 Identities = 81/313 (25%), Positives = 140/313 (44%), Gaps = 19/313 (6%)

Query: 523   DGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
             +G  V++ C++E Y +  Q+TW+     ++ S+ +++ Y+D  VA L ++++   D GT+
Sbjct: 32508 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGTY 32566

Query: 582   TCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
              C   N  G  SS  EL V+    + D+    T+              +LE  PP F+  
Sbjct: 32567 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMR---LLER-PPEFTLP 32622

Query: 640   PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKIT 698
                +    G ++     +   PEP + W   G++I P D +     ESD  +Y   L I 
Sbjct: 32623 LYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY--QLTIN 32680

Query: 699   NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-----RQGESVI 753
             +V    +  YTVVA N+ GE S    L +          + P+   ++     ++G+SV 
Sbjct: 32681 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 32740

Query: 754   LSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENS 810
                +V G P PT+ W K+ +P+   P      +G  +    ++    +D G Y + A N+
Sbjct: 32741 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 32800

Query: 811   EGIAETSAVITVE 823
              G     A + VE
Sbjct: 32801 AGSTSCQAHLQVE 32813



 Score =  104 bits (249), Expect = 3e-20
 Identities = 172/833 (20%), Positives = 327/833 (39%), Gaps = 71/833 (8%)

Query: 736   QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK 795
             +++   +SM V +GES   S    G P PT+TW +  + +          T   +  +  
Sbjct: 33489 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 33548

Query: 796   KVK--DEGVYTLKAENSEGIAETSAVITVEEP--TEENAEPPLFINRFQEITVKEKGTIK 851
              V+  DEG Y++  ENSEG  E    +T+++   TE+    P  + +  E  VK    +K
Sbjct: 33549 SVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV-KSPEPRVKSPEAVK 33607

Query: 852   LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
                RV ++P PS     + + +SP+ET  +    E ++ +  +   +I     K  AS  
Sbjct: 33608 SPKRV-KSPEPS-----HPKAVSPTET--KPTPTEKVQHLPVSAPPKITQF-LKAEASKE 33658

Query: 912   AGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM 970
               K +     ++   ++VT+ K  +K  E    +          T   K  +  +   G 
Sbjct: 33659 IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ---FHYSADGTYELKINNLTESDQGE 33715

Query: 971   DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK-------DQETSTMLVVKETIPE----- 1018
                EI  EG                + + + K       DQ+T+   V ++T P+     
Sbjct: 33716 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 33775

Query: 1019  -----FIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGEII-KPKKNKYDFEKRGHI 1071
                   +  LQD  V    VA   V+   E     +W +DG+ I +  K K   +K G  
Sbjct: 33776 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 33835

Query: 1072  RKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131
               L I  T   D G Y+C +++ + +   +  +L  + I   + QKV+   + T EI   
Sbjct: 33836 --LEIHKTDTSDSGLYTCTVKNSAGSVSSSC-KLTIKAIKDTEAQKVS--TQKTSEITPQ 33890

Query: 1132  KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY--SCEVGNSKCTAI- 1188
             K  A+V+       ++ S  I+++    ++KL + +    +A +   S EV  S  T++ 
Sbjct: 33891 K-KAVVQEEISQKALR-SEEIKMSEAKSQEKLALKE----EASKVLISEEVKKSAATSLE 33944

Query: 1189  LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE------------TLDVTWYKKKSVI 1236
              ++    I  T +  E +   A   A+ T    +E              DV W      +
Sbjct: 33945 KSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVEL 34004

Query: 1237  EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-----VEFPPKIV 1291
              ++E++        +TL I++ +  D+   TC+    +   K + ++     +   P  +
Sbjct: 34005 TNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFI 34064

Query: 1292  DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                R   I  G +V    +    P P  EW  N+  I    +   S      SL I+   
Sbjct: 34065 SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 34124

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              +D+G Y ++ +N  G      ++ +L     P +  +L   S   ++       +   +
Sbjct: 34125 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR-TSGDTSLQGSFSSQSVQMS 34183

Query: 1412  IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
                    +    ++   S+  +     S Q++ +         + + + IS+ ++     
Sbjct: 34184 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 34243

Query: 1472  KVIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
               + +  I+   P +E    +I+ +  + + + C F G P P+VTW   G+K+
Sbjct: 34244 SKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 34296



 Score =   99 bits (238), Expect = 7e-19
 Identities = 108/439 (24%), Positives = 183/439 (41%), Gaps = 33/439 (7%)

Query: 1044  TADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT--AEV 1100
             T ++ W R+ GE      +K   EK  +  +L I N   +D G+Y   L + S +  A V
Sbjct: 24980 TPEITWSREEGEFT----DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 25035

Query: 1101  TVVELP-PEIITRLQNQKVNKGNK-ATFEIELTKGDALVR-WFKDGSEIQFSNHIQLTID 1157
             TV  L  P     L  ++V K +    +E  +  G A V+ +  D  E     +  ++  
Sbjct: 25036 TVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSK 25095

Query: 1158  GKKQKLK--------IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
               K   K        IY   +    E+   V      A+   E PS    + L +     
Sbjct: 25096 CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDV---- 25151

Query: 1210  ANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
             + T A L  E P  D    V  Y  +   + TEK++++++ K    ++   +   + ++ 
Sbjct: 25152 SQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 25211

Query: 1268  CVLLDAKSTTKLKVEVVEFPPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDE 1320
                 + K  +  +V  V    K +  +         Y I+ G D+ + +     P+PN  
Sbjct: 25212 VKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNIS 25271

Query: 1321  WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
             W+ + + +K+         + S  L IK+    D G Y +   N+ G A   ++V +L+K
Sbjct: 25272 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 25331

Query: 1381  PSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT 1438
             P PP G     E+ +  + I W+ P  TG   I  Y+VE ++  TT W  V   + +T  
Sbjct: 25332 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI 25391

Query: 1439  SIQNLKTNSSYRFRAYAVN 1457
              I  LKT + Y+FR +A N
Sbjct: 25392 KITKLKTGTEYQFRIFAEN 25410



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 60/204 (29%), Positives = 102/204 (50%), Gaps = 10/204 (4%)

Query: 713   VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             ++R    ++ I  K+ +GE   P + + +K +  + GE+  LS Q+VG P P I W +  
Sbjct: 31440 LSRPRRTAMSIKTKLTSGEA--PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFG 31497

Query: 773   KPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
             K +   +     SDG TH++T++  ++ +DEGVYT  A N  G  ETS+ + ++   + +
Sbjct: 31498 KELIQSRKYKMSSDGRTHTLTVMTEEQ-EDEGVYTCIATNEVGEVETSSKLLLQATPQFH 31556

Query: 830   AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
                PL    +  +      T++L       PVP++TW+   +++  SE IT         
Sbjct: 31557 PGYPLKEKYYGAVG----STLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTH 31612

Query: 890   LVITNVDSEIDSGDYKCVASNSAG 913
             LV+ NV  +  +G YK   SN  G
Sbjct: 31613 LVMKNVQRKTHAGKYKVQLSNVFG 31636



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 61/201 (30%), Positives = 103/201 (51%), Gaps = 13/201 (6%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LP----TKSDGDT 786
           + P   +PL+S++V +G +    A + G P P ++W ++ + +    LP    + SDG  
Sbjct: 4   QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
             +TI    K  + G Y+LKA N  G A ++A + V+  T     PP F+ R Q +TV++
Sbjct: 64  -KLTIPAVTKA-NSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQ 117

Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
              ++L  RVT  P P + +YR+   I  S     + +G+   L+I     E DSG Y  
Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE-DSGTYSV 176

Query: 907 VASNSAGKSSHGARVTIDVEK 927
            A+NS G+++  A + +  E+
Sbjct: 177 NATNSVGRATSTAELLVQGEE 197



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 58/201 (28%), Positives = 101/201 (50%), Gaps = 13/201 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTH 787
            +P  V++P+ S    +G++     +VVG P P   W  + + +       +  K DG T 
Sbjct: 1456 KPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG-TQ 1513

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
            S+ I+ P    D G +T+ A+N  G +  S ++TVE    E+   P+F+ + + + +KE 
Sbjct: 1514 SLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVE--AVEHQVKPMFVEKLKNVNIKEG 1570

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI--DSGDYK 905
              +++  R T NP P I W +N++II P +      +G   E  +  +DS +  DS  Y 
Sbjct: 1571 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL-KIDSTVSQDSAWYT 1629

Query: 906  CVASNSAGKSSHGARVTIDVE 926
              A N AG+ +   +V ++VE
Sbjct: 1630 ATAINKAGRDTTRCKVNVEVE 1650



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 54/175 (30%), Positives = 80/175 (45%), Gaps = 9/175 (5%)

Query: 1298  RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK----CKHTKPSIDSKSAS--LTIKKVE 1351
             ++K G  V +  D    P P  EW  N  +I+K     + TK  +    A   L+I K  
Sbjct: 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395

Query: 1352  NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
               D G Y +   N  G     ++V + D+PSPP    + +I + S  + WD P + G S 
Sbjct: 16396 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 16455

Query: 1412  IIYYVVEYQEID--TTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
             I +YV++ ++      EW  V N   + +  I  L  N  Y FR  AVN+  ISD
Sbjct: 16456 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISD 16510



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 61/202 (30%), Positives = 99/202 (49%), Gaps = 9/202 (4%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
           PTF++  ++  V EGS    E  +   P P+++W   G+ I       V I  SD     
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR--- 62

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           + L I  V K   G Y++ A N  G+A+    L +K  E  PP  ++ L+SM VRQG  V
Sbjct: 63  AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA-ETAPPNFVQRLQSMTVRQGSQV 121

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  +V G P P + + ++   +++        +GD +S+ I +    +D G Y++ A N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP-EDSGTYSVNATN 180

Query: 810 SEGIAETSAVITVEEPTEENAE 831
           S G A ++A + V+   E  A+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAK 202



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 109/506 (21%), Positives = 193/506 (38%), Gaps = 39/506 (7%)

Query: 598   LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
             ++ +A L D G+ + +             + L  + P      K   V E  +++  C  
Sbjct: 13536 VVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE- 13589

Query: 658   VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             V        W F+ EE + D +  + ++ D+ +Y   L+I +     +  Y V   N  G
Sbjct: 13590 VNTEGAKAKW-FRNEEAIFDSSKYIILQKDL-VY--TLRIRDAHLDDQANYNVSLTNHRG 13645

Query: 718   EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775
             E        I   E+E  +++EPLK +   + +SV    + V     T+ W KN + V  
Sbjct: 13646 ENVKSAANLIV--EEEDLRIVEPLKDIETMEKKSVTFWCK-VNRLNVTLKWTKNGEEVPF 13702

Query: 776   -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
                +  + D   H +TI K     DEG Y + A   + +AE   ++ +E PTE       
Sbjct: 13703 DNRVSYRVDKYKHMLTI-KDCGFPDEGEYIVTAGQDKSVAE---LLIIEAPTE------- 13751

Query: 835   FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
             F+   ++ TV E        +++R    ++ WYRN   I   +      DG    L+I +
Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 13810

Query: 895   VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
                + D  +Y C   +   +    AR+ ++   V  ++  Q   E      V L      
Sbjct: 13811 CRLD-DECEYACGVEDRKSR----ARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKD 13865

Query: 955   TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014
              V  +W  N   +   D  +++ EG+            D G  + I KD+E    L +  
Sbjct: 13866 KVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLEL-A 13924

Query: 1015  TIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
               P+     QD  V       + V  ++   A+  W ++ E +  K      +       
Sbjct: 13925 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK----TIDTTAEQTS 13980

Query: 1074  LYIRNTSVHDEGEYSCILRDESCTAE 1099
               I      D+G Y  +L+++   AE
Sbjct: 13981 FRILEAKKGDKGRYKIVLQNKHGKAE 14006



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 61/211 (28%), Positives = 94/211 (44%), Gaps = 9/211 (4%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  KP +    EG     + ++V  P P+  W   G++IV D    V I+ D      
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESV 752
            ++  T       G +TVVA NR G +S+ ++L ++  E +  P  +E LK++ +++G  +
Sbjct: 1517 IVPAT---PSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQL 1573

Query: 753  ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAE 808
             +  +  GNP P I W KN+    P K    + +G      +     V +D   YT  A 
Sbjct: 1574 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633

Query: 809  NSEGIAETSAVITVE-EPTEENAEPPLFINR 838
            N  G   T   + VE E  E   E  L I R
Sbjct: 1634 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPR 1664



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 70/270 (25%), Positives = 116/270 (42%), Gaps = 25/270 (9%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  +++L+P     G   +F   + G P+P+I+W+++  ++      +  +D     TL+
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY-TLL 3297

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP-LSDHGSEMTVXXXXXXXXXXXXADI 628
            + E FPEDA  +TC AKN  G A+++  L VE P +     EM V               
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV--------------- 3342

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                PP      +     EG     +CR V+  +  ++W  K ++I P     +    D 
Sbjct: 3343 ---YPPAIITPLQDTVTSEGQPARFQCR-VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT 3398

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            +     L+I       EGTYT VA N  G+ S    L ++  E    + IE    M +++
Sbjct: 3399 YQ----LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKE 3454

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKAL 778
              S  LSA+  G     +   K N+ ++ L
Sbjct: 3455 FSSSFLSAEEEGLHSAELQLSKINETLELL 3484



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 51/198 (25%), Positives = 92/198 (46%), Gaps = 3/198 (1%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             ++ G +V L + Y+  P+P+  W+ +   +K+ +  + S      +L+IK  +    G Y
Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 28561

Query: 1359  KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
              + L+N      V + V  L  PS P  P    EI + S+ + WD PE+ G   I  Y +
Sbjct: 28562 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 28621

Query: 1418  EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             E +E   T W  V  ++ +T   + NL  ++ Y+FR  A N   +S     +       +
Sbjct: 28622 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPL-VSSIIVAKHQ 28680

Query: 1477  TKIQSPTVEKPLKNITTE 1494
              +I  P  +  + N+T++
Sbjct: 28681 FRIPGPPGKPVIYNVTSD 28698



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 149/701 (21%), Positives = 260/701 (37%), Gaps = 54/701 (7%)

Query: 639   KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
             KP++  V EG      C     P P + WL KG+ +       V        Y S  +I+
Sbjct: 33493 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK----YKSTFEIS 33548

Query: 699   NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
             +V+   EG Y+VV  N EG+      L I+        V  P +   V+  E  + S + 
Sbjct: 33549 SVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR---VKSPEPRVKSPEA 33605

Query: 759   VGNPR----PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
             V +P+    P  +  K   P +  PT ++   H + +  P K+       LKAE S+ IA
Sbjct: 33606 VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH-LPVSAPPKI----TQFLKAEASKEIA 33660

Query: 815   E-----TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARVTRNPVPSITWYR 868
             +      S+V+  +E T       L  N   +      GT +L +  +T +         
Sbjct: 33661 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI 33720

Query: 869   NNEIISPSETITQNFDGENIELVITNVD--SEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             + E    S+T  Q F G+  + +   V   SE    D K   S    K+   A   I   
Sbjct: 33721 SGE-GGTSKTNLQ-FMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS-S 33777

Query: 927   KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYHNKKEISGMDHREIIQEGRXXXXX 985
             K   V  LQ +  + +         T     T  W  + K I+     ++ ++       
Sbjct: 33778 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 33837

Query: 986   XXXXXXXDVGVIKCIVKDQETS-------TMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
                    D G+  C VK+   S       T+  +K+T  + +   +  E+  +  A+++ 
Sbjct: 33838 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 33897

Query: 1039  EINSETADVVWERDGEI-IKPKKNKYDFEKRGHIRKLYIR---NTSVHDEGEYSCILRDE 1094
             EI+ +       R  EI +   K++     +    K+ I      S     E S +  + 
Sbjct: 33898 EISQKAL-----RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 33952

Query: 1095  SCTAEVT-VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
             + T++ +  V    EI        +N+G +   +  +  G   V+W  +G E+  S   +
Sbjct: 33953 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA-GATDVKWVLNGVELTNSEEYR 34011

Query: 1154  LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV--EEPSINFTLRLPEFIL 1207
               + G  Q L I      D G  +C    + G  KC   LT+  E       +  P    
Sbjct: 34012 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQN 34071

Query: 1208  VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             +    +   T EI  E + ++ W+K    I  +   ++       +L IR  +  D  +Y
Sbjct: 34072 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 34131

Query: 1267  TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
             T    + +        ++   P + +  RE  ++   D +L
Sbjct: 34132 TIKAKNFRGQCSATASLMVL-PLVEEPSREVVLRTSGDTSL 34171



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 65/245 (26%), Positives = 104/245 (42%), Gaps = 31/245 (12%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E+   P+FV K       +G T +F+ +V G P P+  WF     I      ++   +D 
Sbjct: 1452 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1511

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              +L+I    P D+G +T VA+N AG +S +  L VEA                      
Sbjct: 1512 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA---------------------- 1549

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
               +   + P F +K K   + EGS + ++ R    P PDI WL   + IVP +   + I
Sbjct: 1550 ---VEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRI 1606

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
            E       + LKI +        YT  A+N+ G  +    + ++    EP    EP + +
Sbjct: 1607 EGTKGE--AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP----EPERKL 1660

Query: 745  IVRQG 749
            I+ +G
Sbjct: 1661 IIPRG 1665



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 94/421 (22%), Positives = 165/421 (39%), Gaps = 35/421 (8%)

Query: 1074  LYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEIITR-LQNQKVNKGNKAT-FE 1127
             + I+N     +G YS + ++E+     T  V V+++P  + T  L +   N+  K T F 
Sbjct: 17507 MVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFS 17566

Query: 1128  IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
              E   G  +  +  +  E        +T    +Q   +    L     Y   +       
Sbjct: 17567 PEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIG 17624

Query: 1188  ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW-------------YKKKS 1234
             +    E S    +R P  I VP   +     E+   T+ +TW             Y  +S
Sbjct: 17625 MGPFVETSEALVIREP--ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES 17682

Query: 1235  VIEDTEKFTLISD--VKKRTLIIRKCTEDDQCEYTCVLLDAKS-------TTKLKVEVVE 1285
              +  TEKF  +++  +  R   ++   E D  EY    ++          T  +  +   
Sbjct: 17683 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 17742

Query: 1286  FPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
              PP + +D+  +  I+ G    L   Y   P+P   W  +   + +   T       + +
Sbjct: 17743 APPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLA 17802

Query: 1345  LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDE 1403
             L   K + +D+G Y + +EN+ G       V ++D+P PP G  +  E+    + I W  
Sbjct: 17803 LEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKP 17862

Query: 1404  PENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
             P + G S I  Y++E +E+    W+ V + + KT   +  L     Y FR +A N   IS
Sbjct: 17863 PLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 17922

Query: 1463  D 1463
             D
Sbjct: 17923 D 17923



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 49/187 (26%), Positives = 78/187 (41%), Gaps = 6/187 (3%)

Query: 1299  IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAG 1356
             +K G  + L    +  P P   W  +       +  +  ID++  S+  ++ K + +D G
Sbjct: 19140 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 19199

Query: 1357  IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
              Y +   N  G       V +LDKP P     I+++ S    +CWD PE+ G   I  Y+
Sbjct: 19200 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYI 19259

Query: 1417  VEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
             +E  E     W +      T  T++  L   + Y FR  A N++        TE   VI 
Sbjct: 19260 LEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKI---GTGPPTESKPVIA 19316

Query: 1476  ETKIQSP 1482
             +TK   P
Sbjct: 19317 KTKYDKP 19323



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 124/586 (21%), Positives = 227/586 (38%), Gaps = 62/586 (10%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            +K  K   V E      EC +     P + WL  G EI   E   + ++  +H     L 
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ----LI 2939

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            I N        YT V  N +  A+L +          P  +   LK +   + +++    
Sbjct: 2940 IMNTSTEDSAEYTFVCGNDQVSATLTVT---------PIMITSMLKDINAEEKDTITFEV 2990

Query: 757  QVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
              V     +  W KN   +K+      ++   THS+ I +     D   YT  A    G 
Sbjct: 2991 -TVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNI-RNVHFGDAADYTFVA----GK 3044

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A ++A + VE    E      F    ++I V EK        V+  P  ++ W ++++ +
Sbjct: 3045 ATSTATLYVEARHIE------FRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQEL 3097

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
              ++ I    +     L+I +     D+G Y  VA  +       A++ ++   V  ++ 
Sbjct: 3098 QITDRIKIQKEKYVHRLLIPSTRMS-DAGKYTVVAGGNVST----AKLFVEGRDVR-IRS 3151

Query: 934  LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXX 990
            ++K  +  E +  ++E + +   V   WY +  EI+    +  + + E R          
Sbjct: 3152 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3211

Query: 991  XXDVGVIKCIV-KDQETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVV 1048
              D G    +  +++ + T+ V     P+ +++LQ   V+  K      V        + 
Sbjct: 3212 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEVTV 1102
            W ++ +++     K  F   G    L +      D   Y+C  +++      S +  V V
Sbjct: 3272 WYKEEQLLSTGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330

Query: 1103 VEL----------PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152
             E+          PP IIT LQ+   ++G  A F+  ++  D  V W+    +I+ S   
Sbjct: 3331 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFF 3390

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEP 1194
            ++T      +L+I +   +D G Y    S  VG    TA L++E P
Sbjct: 3391 RMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 64/231 (27%), Positives = 104/231 (45%), Gaps = 35/231 (15%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ--DFQMYYDDDN 564
           + AP F + L+     +GST  FE  + G+P P+++WFR   +I  S     Q+ + D  
Sbjct: 3   TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            A L I  V   ++G ++  A N +G A+ST             +E+ V           
Sbjct: 63  -AKLTIPAVTKANSGRYSLKATNGSGQATST-------------AELLVKA--------- 99

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
                E  PP F ++ ++  V +GS + L+ R+  IP P + +   G EI    +  ++ 
Sbjct: 100 -----ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQ 154

Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735
           E D++     L I        GTY+V A N  G A+    L ++ GE+E P
Sbjct: 155 EGDLYS----LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ-GEEEVP 200



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 9/212 (4%)

Query: 1288  PKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             P IV++  EY     IK G  + +    Q  P P   W  +   I+K  + + +    S 
Sbjct: 28882 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28941

Query: 1344  SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWD 1402
             SL ++       G+Y +  +N  G A  E+ V + D P    G      I    + + WD
Sbjct: 28942 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 29001

Query: 1403  EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVD 1460
              P N G + I +Y++E +E     W  +++  + Q  T+I+ +  N  Y+FR  AVN+  
Sbjct: 29002 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGN-EYQFRVSAVNKFG 29060

Query: 1461  ISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
             +    ++      I+ T   +P + +P  NIT
Sbjct: 29061 VGRPLDSDPVVAQIQYTVPDAPGIPEP-SNIT 29091



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 41/112 (36%), Positives = 60/112 (53%), Gaps = 2/112 (1%)

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            ++P    P  E     P  +  L+   T +G   +F+C+V G    +++W+ +   IKPS
Sbjct: 3329 EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPS 3387

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            + F+M   +D    L I E +PED GT+T VA NA G  SST  L +EAP S
Sbjct: 3388 RFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 13/205 (6%)

Query: 476  DENNYTQYLQ-KKLNEKIDKL---PVFE-KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFE 530
            +E  ++  LQ  K+NE ++ L   PV+  K  SE++   PIF++++       G      
Sbjct: 3464 EEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3523

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
              V G P+P+I WF    ++ PS D++  +D D+  +L+I     ED G +TC+A N  G
Sbjct: 3524 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD-HSLIILFTKLEDEGEYTCMASNDYG 3582

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG-IPPTFSKKPKAQYVDEGS 649
                +  L + +    H    T              + L G  PP F K+ K     +G 
Sbjct: 3583 KTICSAYLKINSKGEGHKDTET------ESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 3636

Query: 650  DILLECRLVAIPEPDIAWLFKGEEI 674
              + E  +V  P P + W  + +++
Sbjct: 3637 PAIFEYTVVGEPAPTVTWFKENKQL 3661



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 80/324 (24%), Positives = 121/324 (37%), Gaps = 30/324 (9%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            DEG+   +    V           +  E +  E I   IE +M  + S       +    
Sbjct: 3410 DEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHS 3469

Query: 706  GTYTVVAVNREGE--ASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGN 761
                +  +N   E  +  P+       EKE   P  I+ + +  +  G+   LS  V+G 
Sbjct: 3470 AELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGI 3529

Query: 762  PRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P+P I W  N     P        DGD HS+ IL  K ++DEG YT  A N  G    SA
Sbjct: 3530 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTK-LEDEGEYTCMASNDYGKTICSA 3588

Query: 819  VITVEEPTEENAE------------------PPLFINRFQEITVKEKGTIKLVARVTRNP 860
             + +    E + +                  PP F+   + I   +         V   P
Sbjct: 3589 YLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEP 3648

Query: 861  VPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P++TW++ N+ +  S   TI  N +G      I N     DSG Y C A N  G+S+  
Sbjct: 3649 APTVTWFKENKQLCTSVYYTIIHNPNGSG--TFIVNDPQREDSGLYICKAENMLGESTCA 3706

Query: 919  ARVTIDVEKVTFVKHLQKSYETEE 942
            A + + +E         K+  T E
Sbjct: 3707 AELLVLLEDTDMTDTPCKAKSTPE 3730



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 64/217 (29%), Positives = 88/217 (40%), Gaps = 28/217 (12%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            EG  P F K+     +  G    L   ++ IP+P I W F G  + P  +     + D H
Sbjct: 3499 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3558

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT---GEKE------------- 733
                 L I   K   EG YT +A N  G+      LKI +   G K+             
Sbjct: 3559 S----LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3614

Query: 734  -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT 786
                 PP  ++ LK +   QG   I    VVG P PT+TW K NK +      T      
Sbjct: 3615 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3674

Query: 787  HSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             S T I+   + +D G+Y  KAEN  G +  +A + V
Sbjct: 3675 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 36/96 (37%), Positives = 61/96 (63%), Gaps = 1/96 (1%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           ++  P FV++L+      GS V+ + +V G P P + ++R  A I+ S DFQ+  + D +
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-L 158

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +L+I E +PED+GT++  A N+ G A+ST EL+V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 64/298 (21%), Positives = 122/298 (40%), Gaps = 11/298 (3%)

Query: 1186  TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTL 1244
             TA   VE P I+   +  + I+V A     L  ++  + L  + W +    IE++ +  +
Sbjct: 24542 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 24601

Query: 1245  ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKR 1301
              +   K  LI++     D  +Y     +   +    + V+V++ P P     +       
Sbjct: 24602 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 24661

Query: 1302  GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
                +T     Q        ++V  +   +   T  + +  + SL + K+   +  ++++ 
Sbjct: 24662 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 24721

Query: 1362  LENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
               N  G  +   +  +L K     P PP    +  I   S+ +CW+ P++ G S II Y+
Sbjct: 24722 AVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 24781

Query: 1417  VEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             VE ++     WI  + + IT  +  +  L  +  Y FR  A N   + + S  T YYK
Sbjct: 24782 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYK 24839



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 72/330 (21%), Positives = 133/330 (40%), Gaps = 40/330 (12%)

Query: 646   DEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             +EG  +   C++    +   + W F   ++   E   +  E  +    ++L + ++ K  
Sbjct: 32507 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV----AILYVKDITKLD 32562

Query: 705   EGTYTVVAVNREGEASLPIVLKIK------------TGEK------------EPPQVIEP 740
             +GTY    VN  GE S    L +K            T +K             PP+   P
Sbjct: 32563 DGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLP 32622

Query: 741   LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALPTKSDGDTHSITILKP 794
             L +     GE+V     +  +P P +TW K+ + +      K    +SD   + +TI   
Sbjct: 32623 LYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI-NS 32681

Query: 795   KKVKDEGVYTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
                 D+  YT+ A N   E   +    +T+  P  ++   P+F         +E  ++  
Sbjct: 32682 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 32741

Query: 853   VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
               RV+  P P++ W ++ + +S    I    +G +   +        D+G Y+  A+N+A
Sbjct: 32742 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTA 32801

Query: 913   GKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             G +S   +  + VE++ + K   KS E  E
Sbjct: 32802 GSTS--CQAHLQVERLRYKKQEFKSKEEHE 32829



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)

Query: 510  PIFVEKLRP-KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P FV+KL   K    G ++Q EC++ G P  +++WFR  + +  S  + M + + +VA L
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFIN-SVALL 7349

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             I E   ED+G + C A N  G AS +T L V+AP
Sbjct: 7350 TINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 7384



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 54/172 (31%), Positives = 90/172 (52%), Gaps = 16/172 (9%)

Query: 678   ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---P 734
             E  S+  ES +   C+ + +T +   QE  + V A N +G++  P VL +    K+    
Sbjct: 25184 EKWSIVAESKV---CNAV-VTGLSSGQEYQFRVKAYNEKGKSD-PRVLGVPVIAKDLTIQ 25238

Query: 735   PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
             P +  P  +  ++ GE + +   V+G PRP I+W K+ +P+K     +  +T + T+L  
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 25298

Query: 795   KK-VKDE-GVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEIT 843
             K+  KD+ G YT+ A NS G A E  +VI +E+P      PP+   RF E++
Sbjct: 25299 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP-----GPPVGPVRFDEVS 25345



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 12/163 (7%)

Query: 1315  PQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-----TIKKVENTDAGIYKLRLENNCGHA 1369
             P+ +    + + I++KC+  +    + SA++     T+ ++   +  I+++R EN  G  
Sbjct: 19247 PEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 19306

Query: 1370  DVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                 +  ++     DKP  P  P + ++    + + W+ PE  G  +I  Y +E +E  +
Sbjct: 19307 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 19366

Query: 1425  TEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             T W+ V    I + +  +QNL  +  Y+FR  A NE+ I + S
Sbjct: 19367 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPS 19409



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 75/299 (25%), Positives = 130/299 (43%), Gaps = 15/299 (5%)

Query: 319   EAAKVKKQVF--VPPKLPDVEKTELEQPLFSYEDIVESK-KDENEIIQEKQTLEELPKED 375
             EA KV  Q    + P+   V + E+ Q     E+I  S+ K + ++  +++  + L  E+
Sbjct: 33875 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEE 33934

Query: 376   VPEQYTITPRKSSAQKIDEIVDEVTIKKRLNP-FEIFYTPVEVRCGDTVFAVYSYVAETD 434
             V +    +  KS   +      + + + R +   + F T + +  G  +    +    TD
Sbjct: 33935 VKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD 33994

Query: 435   EAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDK 494
                 ++ G  L    T+++++ Y      +      A +  DE   T     K  E I K
Sbjct: 33995 VKW-VLNGVEL----TNSEEYRYGVSGSDQTLTIKQASH-RDEGILTCI--SKTKEGIVK 34046

Query: 495   LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
                ++   S+E S AP F+ + R ++  +G  V F C++ G P P+I WF+    I  S 
Sbjct: 34047 CQ-YDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 34105

Query: 555   DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
             +  +     NV +L IR     D+G +T  AKN  G  S+T  L+V  PL +  S   V
Sbjct: 34106 NVSI-SRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-LPLVEEPSREVV 34162



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 69/297 (23%), Positives = 126/297 (42%), Gaps = 18/297 (6%)

Query: 1187  AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI 1245
             A+ T E P I   ++L   + V A T   L   +  +    +TW K   +++  ++ T+ 
Sbjct: 14608 AVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE 14667

Query: 1246  SDVKKRTLIIRKCTEDDQCEYT--CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
             +  KK T+ I      D   Y    V +  ++T  ++V V++ P     ++    I   +
Sbjct: 14668 NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFD----ITDVT 14723

Query: 1304  DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSIDSKSASLTIKKVENTDAGIYK 1359
             + + L+ +          I N  + ++   +    K S   K  +    K+      I++
Sbjct: 14724 NESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFR 14783

Query: 1360  LRLENNCGHAD-VEMN-VTILDKPSPPGKPNILE---IDSSSINICWDEPENTGNSTIIY 1414
             +  EN  G  + V+ + +T   +  PPG P  LE   I   ++ + W EP++ G S I  
Sbjct: 14784 VAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITG 14843

Query: 1415  YVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             Y VE  + DT +W+    +    T+  ++ L     YRFR  A N       S++TE
Sbjct: 14844 YWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTE 14900



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 62/257 (24%), Positives = 110/257 (42%), Gaps = 16/257 (6%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
             ++W K    ++++E         K TL I+   ++   +YT +L +A     + + V+  
Sbjct: 28522 ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITL 28581

Query: 1287  -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSIDSKSA 1343
              PP        +   +   V L  D    P+ N    +    I+K     T   +   S 
Sbjct: 28582 GPPSKPKGPIRFDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 28638

Query: 1344  SLTIKKVEN--TDAGI-YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSS 1395
             + T  KV N   DA   +++R EN  G +   ++  I+ K     P PPGKP I  + S 
Sbjct: 28639 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 28698

Query: 1396  SINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRA 1453
              +++ WD P   G S +  + VE +E ++  W  ++   I+  +     L     Y+FR 
Sbjct: 28699 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 28758

Query: 1454  YAVNEVDISDASETTEY 1470
             YA N   +S  S+ +++
Sbjct: 28759 YAENSAGLSSPSDPSKF 28775



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 2/104 (1%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            SE +++   F  +++     +G  V F C++ GYP P+I W++    IK  + +QM +  
Sbjct: 1284 SESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ 1343

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APL 604
            D  A+L I  V PED G +T  A N  G A  + +L VE  APL
Sbjct: 1344 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1387



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 9/185 (4%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNK-YDFEKRGHIRKL 1074
            P F + LQ   V E   A  E  I+     +V W RDG++I                 KL
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 1075 YIRNTSVHDEGEYSCILRDES----CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEI 1128
             I   +  + G YS    + S     TAE+ V     PP  + RLQ+  V +G++   ++
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125

Query: 1129 ELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             +T     +V++++DG+EIQ S   Q++ +G    L I +   +D+G YS    NS   A
Sbjct: 126  RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRA 185

Query: 1188 ILTVE 1192
              T E
Sbjct: 186  TSTAE 190



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 14/281 (4%)

Query: 1107  PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
             P I  R+++ +V  G    F + + +K  A V+W+ +G E+Q S+ I  T       L+I
Sbjct: 33301 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 33360

Query: 1166  YDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPE--FILVPANTDAYLTVEIP 1221
              DC  DD+G Y     N K  A    T++    ++T    +     VP +    LT    
Sbjct: 33361 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELT---R 33417

Query: 1222  DETLDVTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS----T 1276
              E   V+ +KK S +E +     + S + +    +         E     L+ KS    +
Sbjct: 33418 TEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKS 33477

Query: 1277  TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             T  K++      +I+   R   +  G       D    P P   W+   +++      + 
Sbjct: 33478 TTRKIKTT-LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQV 33536

Query: 1337  SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             +     ++  I  V+ +D G Y + +EN+ G  + E  +TI
Sbjct: 33537 TTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 33577



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 80/400 (20%), Positives = 138/400 (34%), Gaps = 13/400 (3%)

Query: 1282  EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             E +   P IV   ++  +   S     V     P+P   W  + K I +    K S D  
Sbjct: 33773 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG 33832

Query: 1342  SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILEIDSSSINIC 1400
                L I K + +D+G+Y   ++N+ G       +TI   K +   K +  +    +    
Sbjct: 33833 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKK 33892

Query: 1401  WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE-- 1458
                 E      +    ++  E  + E +++K         + +K +++       V+E  
Sbjct: 33893 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 33952

Query: 1459  VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
                S ASE    +  IK    Q    E     +        ++  +  GV       YR 
Sbjct: 33953 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 34012

Query: 1519  GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITIS 1576
             G        T +                   CI+    G V+    + + ++        
Sbjct: 34013 GVSGSDQTLTIKQASHRDEGILT--------CISKTKEGIVKCQYDLTLSKELSDAPAFI 34064

Query: 1577  NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
             ++   Q    G   L T  I G P PE+ W+KN   +      +I+       + I+   
Sbjct: 34065 SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 34124

Query: 1637  RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
              S S KYTI+A N  G  S   +L V     +P   V++R
Sbjct: 34125 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 34164



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 84/402 (20%), Positives = 149/402 (37%), Gaps = 60/402 (14%)

Query: 541   ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             + W      +  S++++ Y    +  TL I++    D G  TC++K   G      +L +
Sbjct: 33995 VKWVLNGVELTNSEEYR-YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 34053

Query: 601   EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAI 660
                LSD                           P F  +P++Q ++EG ++L  C +   
Sbjct: 34054 SKELSD--------------------------APAFISQPRSQNINEGQNVLFTCEISGE 34087

Query: 661   PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
             P P+I W      I    N+S++   +++     L+I N      G YT+ A N  G+ S
Sbjct: 34088 PSPEIEWFKNNLPISISSNVSISRSRNVYS----LEIRNASVSDSGKYTIKAKNFRGQCS 34143

Query: 721   LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780
                 L +       P V EP + +++R      L     G+          +K   +  +
Sbjct: 34144 ATASLMVL------PLVEEPSREVVLRTSGDTSLQ----GSFSSQSVQMSASKQEASFSS 34193

Query: 781   KSDGDTHSITILKPKKVKDEGVYTLKAE----NSEGIAETSAVITVEEPTEENAE----- 831
              S     S+T +K   +  + + +++      +S      S +  +E  T +  +     
Sbjct: 34194 FSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRG 34253

Query: 832   -PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE- 889
              PP       +I++ E   + +    T  P P +TW      I   E     F  EN + 
Sbjct: 34254 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQE--QGRFHIENTDD 34311

Query: 890   ---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
                L+I +V  + D G Y     N  G  S  A V I +  +
Sbjct: 34312 LTTLIIMDVQKQ-DGGLYTLSLGNEFGSDS--ATVNIHIRSI 34350



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 2/110 (1%)

Query: 495  LPVFEKPTSE-EQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
            +P F+    E   SM AP   E+++ +    GS   F  +V G P P+  W++    I+ 
Sbjct: 2061 IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2120

Query: 553  SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            S     Y+ +DNV  LVIR+V  ED+ +    A N AG  SS   L+V+A
Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 62/302 (20%), Positives = 121/302 (40%), Gaps = 13/302 (4%)

Query: 1227  VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV 1284
             V+W+K    ++ +++ T+ +D     L + K    D   YT  L +    +T  + V+V+
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404

Query: 1285  EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
               P    D +     K    +T          P   +++  +   +  +          S
Sbjct: 15405 GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS 15464

Query: 1345  LTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDS---SSIN 1398
              T+K +       ++++  N  G  + +E+   ++  D   PP  P  +E+ +    ++ 
Sbjct: 15465 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMT 15524

Query: 1399  ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQT-SIQNLKTNSSYRFRAYAV 1456
             I W  P   G S I+ Y++E        W    +++    T + + L+    Y+FR  A 
Sbjct: 15525 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAE 15584

Query: 1457  NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
             N   IS+ S  T   K +    I +P V     ++  +  ++I L     G P P +TW 
Sbjct: 15585 NAAGISEPSRATPPTKAV--DPIDAPKVIL-RTSLEVKRGDEIALDASISGSPYPTITWI 15641

Query: 1517  RD 1518
             +D
Sbjct: 15642 KD 15643



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 82/345 (23%), Positives = 146/345 (42%), Gaps = 28/345 (8%)

Query: 634   PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
             P F ++ +   V   S+  L C++   P+P + W  +G+EI+ D  +   I+     Y  
Sbjct: 31855 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD-GLKYRIQEFKGGYHQ 31913

Query: 694   VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752
             ++ I +V       Y V A N+ G  S    L+++   K   P+ +E + ++   +GE V
Sbjct: 31914 LI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 31972

Query: 753   ILSAQVVGNPRPTITWCK------NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
              +     G P P ITW K      NN   + + T+S     S+      + KD G Y + 
Sbjct: 31973 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRS---FTSLVFPNGVERKDAGFYVVC 32029

Query: 807   AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSIT 865
             A+N  GI +     TVE    +  +PP    R  +++   + ++ L       +    IT
Sbjct: 32030 AKNRFGIDQK----TVELDVADVPDPP----RGVKVSDVSRDSVNLTWTEPASDGGSKIT 32081

Query: 866   WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTI 923
              Y   +  + +E   +          + N+  +  S  ++ +A N  G  K S  +  TI
Sbjct: 32082 NYIVEKCATTAERWLRVGQARETRYTVINLFGK-TSYQFRVIAENKFGLSKPSEPSEPTI 32140

Query: 924   DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
               E  T  + +    E +E + V +  + SH+ STK  + K  I+
Sbjct: 32141 TKEDKT--RAMNYDEEVDETREVSM-TKASHS-STKELYEKYMIA 32181



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 60/267 (22%), Positives = 107/267 (40%), Gaps = 14/267 (5%)

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            + ++I    + ++WYK    +E ++KF +  D  + TL ++ C   DQ  Y  V      
Sbjct: 9604 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC--GPH 9661

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
                K+ V+E  P    + ++  +K G   T+   +   P    EW  N +I+K     K
Sbjct: 9662 IASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHK 9718

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDS 1394
              ++ K   LTI  V   D G Y       C + D+E +  +  +  P      I  I  
Sbjct: 9719 TEVEHKVHKLTIADVRAEDQGQY------TCKYEDLETSAELRIEAEPIQFTKRIQNIVV 9772

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRA 1453
            S       E E + +  I+ +     E+  ++  + +N  +    +I N+  +    +  
Sbjct: 9773 SEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSV 9832

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQ 1480
             A  E    +A  T E Y   KE K++
Sbjct: 9833 IARLE-PRGEARSTAELYLTTKEIKLE 9858



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 60/235 (25%), Positives = 99/235 (42%), Gaps = 33/235 (14%)

Query: 509   APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
             AP   ++++   T  G   Q  CQ+ G P P I W+R    +  S+ ++M   D    TL
Sbjct: 31459 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTL 31517

Query: 569   VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
              +     ED G +TC+A N  G   ++++L+++A    H                     
Sbjct: 31518 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--------------------- 31556

Query: 629   LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                  P +  K K  Y   GS + L    +  P P + W F G++++ +   ++ IE+  
Sbjct: 31557 -----PGYPLKEK-YYGAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSE-NITIENTE 31608

Query: 689   HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPL 741
             H    V+K    +K   G Y V   N  G  +A L + ++ K  +   P VIE L
Sbjct: 31609 HYTHLVMKNVQ-RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL 31662



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 10/209 (4%)

Query: 628   ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
             +  G  P   K+ K      G    L C++V  P PDI W   G+E++      ++ +  
Sbjct: 31454 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 31513

Query: 688   MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV- 746
              H     L +   ++  EG YT +A N  GE      L ++   +  P    PLK     
Sbjct: 31514 TH----TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYG 31567

Query: 747   RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVY 803
               G ++ L    +G P P +TW    K ++     +  +T   T L  K V+ +   G Y
Sbjct: 31568 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKY 31627

Query: 804   TLKAENSEGIAETSAVITVEEPTEENAEP 832
              ++  N  G  +    + +++  ++   P
Sbjct: 31628 KVQLSNVFGTVDAILDVEIQDKPDKPTGP 31656



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 61/251 (24%), Positives = 95/251 (37%), Gaps = 34/251 (13%)

Query: 480   YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539
             Y +   KK+  + D + + E+P        P F   L  K    G  V+F   +  +P P
Sbjct: 32595 YCRRTMKKIKRRTDTMRLLERP--------PEFTLPLYNKTAYVGENVRFGVTITVHPEP 32646

Query: 540   QITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
              +TW++    IKP  + + Y    D  +  L I  V  +D   +T VA+N  G  S   +
Sbjct: 32647 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 32706

Query: 598   LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
             L V   L    ++ T                   + P F +        EG  +  E R+
Sbjct: 32707 LTV--TLHPPPTDST-------------------LRPMFKRLLANAECQEGQSVCFEIRV 32745

Query: 658   VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
               IP P + W   G+ +    NI + I   +  Y   L I +      G Y V A N  G
Sbjct: 32746 SGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYY--ALHIRDTLPEDTGYYRVTATNTAG 32802

Query: 718   EASLPIVLKIK 728
               S    L+++
Sbjct: 32803 STSCQAHLQVE 32813



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 48/166 (28%), Positives = 78/166 (46%), Gaps = 20/166 (12%)

Query: 1047  VVWERDGEIIKPKKN--KYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100
             V W + G+ IKP  N  KY FE    + +L I + +  D+ EY+ + R    ++SC A++
Sbjct: 32648 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKL 32707

Query: 1101  TVVELPPEIITRLQ--------NQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNH 1151
             TV   PP   + L+        N +  +G    FEI ++      ++W KDG  +    +
Sbjct: 32708 TVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN 32767

Query: 1152  IQLTIDG-KKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192
             I++  +G     L I D   +D G Y    +   G++ C A L VE
Sbjct: 32768 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 32813



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 2/126 (1%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534
            +D N+  +Y+ K  N  + ++      T +EQ + P F  +LR      G  V F+C + 
Sbjct: 8950 VDINDSGEYICKAENS-VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAIS 9008

Query: 535  GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
            G     ++W++    +K S + Q  +  DN ATL I +     AG ++C A N  G ASS
Sbjct: 9009 GSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASS 9067

Query: 595  TTELIV 600
            +  LI+
Sbjct: 9068 SARLIL 9073



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 16/157 (10%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             ITN+ + +E  + VVAVN +G +     ++PIV K    E   P V     S  V+ G+ 
Sbjct: 24117 ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE---PDVKPAFSSYSVQVGQD 24173

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDE-GVYTLKAEN 809
             + +   + G P+PTITW K+  P+K     +  D+  +T L  K+  KD+ G Y +   N
Sbjct: 24174 LKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVAN 24233

Query: 810   SEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVK 845
               G    S  ++T+++P     +PP    +F +++ +
Sbjct: 24234 VVGQKTASIEIVTLDKP-----DPPKGPVKFDDVSAE 24265



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 65/275 (23%), Positives = 110/275 (40%), Gaps = 31/275 (11%)

Query: 1415  YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY-RFRAYAVNEVDISDASETTEYY-- 1471
             Y + Y+  D    + VK+ITK        K  + Y    +YA  E+ +    E  +YY  
Sbjct: 32542 YEITYE--DGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA--ELFVKGVREVYDYYCR 32597

Query: 1472  KVIKETKIQSPTVEK---------PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
             + +K+ K ++ T+           PL N T    E++         P+P VTWY+ G+K+
Sbjct: 32598 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKI 32657

Query: 1523  KTA----KATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVI 1573
             K      K T+E+                   Y  +A N +GE   +    V +   P  
Sbjct: 32658 KPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTD 32717

Query: 1574  TISNEDIKQ-----KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KT 1627
             +      K+     + + G        + GIPPP + W K+G  L       I  +    
Sbjct: 32718 STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDY 32777

Query: 1628  SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
               + I++     +  Y + A+NTAG++S +  L+V
Sbjct: 32778 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 32812



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 2/128 (1%)

Query: 476   DENNYTQYLQKKLNEKI--DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
             D+  YT   + K  E     KL V   P   + ++ P+F   L      +G +V FE +V
Sbjct: 32686 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 32745

Query: 534   EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
              G P P + W +    +    + ++ ++  +   L IR+  PED G +   A N AG  S
Sbjct: 32746 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 32805

Query: 594   STTELIVE 601
                 L VE
Sbjct: 32806 CQAHLQVE 32813



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 8/148 (5%)

Query: 695   LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGES 751
             L +T +K+ ++  + V A N  G  SLP   +     KE   PP+++ P + + ++ G+ 
Sbjct: 19785 LVVTGLKEGKKYKFRVAARNAVG-VSLPREAEGVYEAKEQLLPPKILMP-EQITIKAGKK 19842

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAEN 809
             + + A V G P PT  W K    V      +    D+ SI I+K    KD G Y+L AEN
Sbjct: 19843 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 19902

Query: 810   SEGIAETSAVITVEEPTEENAEPPLFIN 837
             S G  +T  +  V        +PP  I+
Sbjct: 19903 SSG-TDTQKIKVVVMDAPGPPQPPFDIS 19929



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 38/197 (19%), Positives = 84/197 (42%), Gaps = 7/197 (3%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533
            Q+PT  +PL+++               G P P+V+W+RDG+ + T+       +  + R 
Sbjct: 4    QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLV 1592
                          Y   A N  G+  ++  + ++ +       + ++    + G +  +
Sbjct: 64   KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
               + GIP P V +Y++G ++++  ++ I+ +     + I E     S  Y++ A+N+ G
Sbjct: 124  QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183

Query: 1653 TSSVEVTLKVYDKPSKP 1669
             ++    L V  +   P
Sbjct: 184  RATSTAELLVQGEEEVP 200



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 1/105 (0%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            E+     +  AP F+ K   +   +G +V F CQV G P+P + W +    +     +++
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKV 1130

Query: 559  YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             Y+       LVI   F +DAG +T V +N  G  S++  L+ EA
Sbjct: 1131 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 26/91 (28%), Positives = 48/91 (52%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+++L+P     G    FE  V G P P +TWF++   +  S  + + ++ +   T +
Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3680

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            + +   ED+G + C A+N  G ++   EL+V
Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCAAELLV 3711



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 10/153 (6%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             + N+ + +E T+ V+AVN  G +    S P+++K +T   E        K +I + G+++
Sbjct: 21951 VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 22010

Query: 753   ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
              +   V+G P+PT+TW K ++ +K     +   T + TIL   +    D G Y L A N 
Sbjct: 22011 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 22070

Query: 811   EGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
              G  E   VIT++    +   PP    +F E++
Sbjct: 22071 VG--EVGDVITIQ--VHDIPGPPTGPIKFDEVS 22099



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 5/136 (3%)

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A+ +    V  P E    PP  ++  + +TV E  ++ L   ++  P P++TWYR +  I
Sbjct: 924  AKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI 983

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
              S      F      L+I    +E DSG + C A N AG  S    + + V +  F K 
Sbjct: 984  ESSIDFQITFQSGIARLMIREAFAE-DSGRFTCSAVNEAGTVSTSCYLAVQVSE-EFEKE 1041

Query: 934  ---LQKSYETEEGKTV 946
               + + + TEE + V
Sbjct: 1042 TTAVTEKFTTEEKRFV 1057



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+ + P F  +L+      G  V   C++ G    Q+ W+R   +++  ++ Q  + D 
Sbjct: 7096 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVD- 7154

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            NVATL I +     +G ++C A N  G ASS+  L    P
Sbjct: 7155 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 7194



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 87/445 (19%), Positives = 153/445 (34%), Gaps = 33/445 (7%)

Query: 540   QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
             ++TW++    +K +  FQ +Y  D    L I  +   D G + C      G + +  + +
Sbjct: 33675 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 33734

Query: 600   VEAPLSDHGSEMTVXXXXXXXXXXXXADILE----GIPPTFSKKP----KAQYVDEGSDI 651
              +A  S H     +            + +        P   S KP      Q     SD 
Sbjct: 33735 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 33794

Query: 652   LLECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
             + +  + A   P P   W   G+ I   +     +  D   +   L+I        G YT
Sbjct: 33795 VAKFAVKATGEPRPTAIWTKDGKAIT--QGGKYKLSEDKGGF--FLEIHKTDTSDSGLYT 33850

Query: 710   VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP-RPTITW 768
                 N  G  S    L IK  +    Q +   K+  +   +  ++  ++     R     
Sbjct: 33851 CTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIK 33910

Query: 769   CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL-KAENSEGIAETSAVITVEEPTE 827
                 K  + L  K +       +L  ++VK     +L K+   E I +TS      E   
Sbjct: 33911 MSEAKSQEKLALKEEAS----KVLISEEVKKSAATSLEKSIVHEEITKTS---QASEEVR 33963

Query: 828   ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
              +AE   F     ++++ E   + L A +       + W  N   ++ SE       G +
Sbjct: 33964 THAEIKAFST---QMSINEGQRLVLKANIA--GATDVKWVLNGVELTNSEEYRYGVSGSD 34018

Query: 888   IELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
               L I    S  D G   C++    G  K  +   ++ ++          +S    EG+ 
Sbjct: 34019 QTLTIKQA-SHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQN 34077

Query: 946   VILECQTSHTVS--TKWYHNKKEIS 968
             V+  C+ S   S   +W+ N   IS
Sbjct: 34078 VLFTCEISGEPSPEIEWFKNNLPIS 34102



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            ++ +AP F + LR   +    T + +C++ G    +++WF+    I  S  +++ + +  
Sbjct: 5035 DRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT 5094

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
             +  +IR V   DAG FTC A N+ G   S+  LIV+ P S
Sbjct: 5095 ASLEIIR-VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 5134



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 1/108 (0%)

Query: 501   PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559
             P S+    AP F E+LR  +    S     C+V G+P+P + W+RQ   II     +++ 
Sbjct: 31846 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 31905

Query: 560   YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
                     L+I  V  +DA  +   A N  G  S T  L VE P   H
Sbjct: 31906 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31953



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 70/320 (21%), Positives = 130/320 (40%), Gaps = 32/320 (10%)

Query: 1271  LDAKSTTKLKVEVVEFPPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             L  + T++ K EV+   P  +D+        R +R+  G +   +++ Q+ P    +W  
Sbjct: 33277 LKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYH 33336

Query: 1324  NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD--VEMNVTILDKP 1381
             N   +++      +  S   +L I      D+G Y+    N  G A     ++VT  D  
Sbjct: 33337 NGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYT 33396

Query: 1382  SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKN-ITKT 1436
             +   +    E+  S        PE T   T  Y V  +++    E  S    VK+ +T+T
Sbjct: 33397 TYASQRRDEEVPRSVF------PELT--RTEAYAVSSFKKTSEMEASSSVREVKSQMTET 33448

Query: 1437  QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             + S+ + + ++S   ++ A+ E  + + S T +      +T + +  + KP +++T    
Sbjct: 33449 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKI-----KTTLAARILTKP-RSMTVYEG 33502

Query: 1497  EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552
             E    +C   G P P VTW R G+ L T+      T + +               Y  + 
Sbjct: 33503 ESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV 33562

Query: 1553  FNDHGEVETSCVVGIQQKPV 1572
              N  G+ E    + IQ+  V
Sbjct: 33563 ENSEGKQEAEFTLTIQKARV 33582



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENR 1532
            E  +  PT+   LKN+T    E + L C   G P P VTWYR+  +++++   + T+++ 
Sbjct: 937  EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG 996

Query: 1533 -XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
                            + C A N+ G V TSC + +Q
Sbjct: 997  IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            ++++ P F  +L+      G++   EC+V G     + WF +   I     +Q  + D N
Sbjct: 6722 DRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSD-N 6780

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            V TL +  +   D G +TCVA N AG       L V+ P S
Sbjct: 6781 VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS 6821



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T +++   P  V    P    +G T +F C+V GYP+P++ W+    +I+ S+ F++ Y 
Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY- 1891

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             D +  L I +    D G     A+N  G      +L ++
Sbjct: 1892 -DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ 1930



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 44/151 (29%), Positives = 70/151 (46%), Gaps = 12/151 (7%)

Query: 686   SDMHMYCSVLKITNVK-----KFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQV 737
             SD    C+ +K+T        + +E ++ V A N +G  S P  L +    K+   PP  
Sbjct: 23019 SDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAF 23077

Query: 738   IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797
                  +  V  GE + +    +G P P +TW K+N P+K     +   T + ++L  K  
Sbjct: 23078 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 23137

Query: 798   --KDEGVYTLKAENSEGIA-ETSAVITVEEP 825
               +D G Y +K  NS G A ET  VI +++P
Sbjct: 23138 CREDVGHYVVKLTNSAGEAIETLNVIVLDKP 23168



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 35/169 (20%), Positives = 68/169 (40%), Gaps = 4/169 (2%)

Query: 807   AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
             AEN  G++         +    + E P      +++T K     +L  ++   P+P I W
Sbjct: 31434 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 31493

Query: 867   YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             YR  + +  S     + DG    L +   + E D G Y C+A+N  G+    +++ +   
Sbjct: 31494 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE-DEGVYTCIATNEVGEVETSSKLLLQAT 31552

Query: 927   KVTFVKH-LQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDH 972
                   + L++ Y    G T+ L          +  W+H +K +   ++
Sbjct: 31553 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSEN 31601



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 3/130 (2%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV 533
            +D+ +  QY    +NE + K     +   +E+ + P F ++L       +G++ + E +V
Sbjct: 9142 VDKGDSGQYTCYAVNE-VGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRV 9200

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G     + W++    I+P+ + ++ + + N   L +R+    DAG +TC   N AG A 
Sbjct: 9201 AGSQPITVAWYKNNIEIQPTSNCEITFKN-NTLVLQVRKAGMNDAGLYTCKVSNDAGSAL 9259

Query: 594  STTELIVEAP 603
             T+ ++++ P
Sbjct: 9260 CTSSIVIKEP 9269



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 36/131 (27%), Positives = 66/131 (50%), Gaps = 5/131 (3%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLP-IVLKIKTGEK-EPP--QVIEPLKSMI-VRQGES 751
             + ++K  Q+ ++ V AVN +G +     + +I+  E+ E P  ++ + LK  + +R G S
Sbjct: 30331 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 30390

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + L   V G P P ITW K    + +       +++S+ I+      D G YT++AEN  
Sbjct: 30391 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQS 30450

Query: 812   GIAETSAVITV 822
             G    + ++ V
Sbjct: 30451 GKKSATVLVKV 30461



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 5/116 (4%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--I 791
            PP ++  LK++ V +GESV L   + G P PT+TW + +  +++           I   +
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
            ++    +D G +T  A N  G   TS  + V+   E   E      +F   T +EK
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKF---TTEEK 1054



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 10/117 (8%)

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMI-VRQGESVILSAQV 758
             +F+    T V ++   E S P+ +     E  PP++     +KS++ V+ G +V L A V
Sbjct: 20190 QFRAIARTAVNISPPSEPSDPVTI---LAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 20246

Query: 759   VGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              G P PT++W K+    KP + +      +  ++ +    + KD G YT+ AENS G
Sbjct: 20247 FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR-KDSGDYTITAENSSG 20302



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 4/120 (3%)

Query: 486   KKLNEKIDKLPVFEK--PTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT 542
             KK ++K  +  V  K  P + E  S  P+ V  L+       S  +F  +  G PRP   
Sbjct: 33752 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 33811

Query: 543   WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             W +    I     +++  +D     L I +    D+G +TC  KN+AG  SS+ +L ++A
Sbjct: 33812 WTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 33870



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 14/140 (10%)

Query: 696   KITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQG 749
             K+T ++  Q   + V+AVN  GE   A +P  + +K    EPP++I      +   ++ G
Sbjct: 18102 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD-RLEPPELILDANMAREQHIKVG 18160

Query: 750   ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI---TILKPKKVKDEGVYTLK 806
             +++ LSA + G P P +TW K ++     PTK+  D   +     ++    +D G+Y+L 
Sbjct: 18161 DTLRLSAIIKGVPFPKVTWKKEDRDA---PTKARIDVTPVGSKLEIRNAAHEDGGIYSLT 18217

Query: 807   AENSEGIAETSA-VITVEEP 825
              EN  G    S  V+ +++P
Sbjct: 18218 VENPAGSKTVSVKVLVLDKP 18237



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 8/149 (5%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQVIE--P--LKSMIVRQGE 750
             +T +       + ++A N  G  S P      I T ++  P ++E  P     +I++ GE
Sbjct: 28842 VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGE 28901

Query: 751   SVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKD-EGVYTLKAE 808
             S+ + A V G P P +TW K+   + K +  +      S ++      +D  GVYT++A+
Sbjct: 28902 SLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 28961

Query: 809   NSEGIAETSAVITVEEPTEENAEPPLFIN 837
             N+ G A+    + V++   +   P  F N
Sbjct: 28962 NASGSAKAEIKVKVQDTPGKVVGPIRFTN 28990



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 73/330 (22%), Positives = 129/330 (39%), Gaps = 42/330 (12%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E +   F  + K   + EG  +   C++   P P IAW   G+ I   E   +    D  
Sbjct: 1287 EAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1346

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               + L+I  V    EG YT  A N +G A       I +G+      +EP   +     
Sbjct: 1347 ---ASLRIPVVLPEDEGIYTAFASNIKGNA-------ICSGKL----YVEPAAPL---GA 1389

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             + I + + V   R       +  P++  P +          + P ++    +   +   
Sbjct: 1390 PTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR----------MSPARMSPARMSPARMSP 1439

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
               + ET      +E   E    P+F+ +       E  T +   +V   P+P   W+ +
Sbjct: 1440 GRRLEET------DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493

Query: 870  NEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VE 926
             + I    T  +    DG    +++    S  DSG++  VA N AG+SS    +T++ VE
Sbjct: 1494 GQQIVNDYTHKVVIKEDGTQSLIIVPATPS--DSGEWTVVAQNRAGRSSISVILTVEAVE 1551

Query: 927  ---KVTFVKHLQKSYETEEGKTVILECQTS 953
               K  FV+ L K+   +EG  + ++ + +
Sbjct: 1552 HQVKPMFVEKL-KNVNIKEGSQLEMKVRAT 1580



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 51/230 (22%), Positives = 89/230 (38%), Gaps = 12/230 (5%)

Query: 693   SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQ 748
             +V  + N+ +  E  + V   N  GE+    + +  T + +     P   E L+++ VR 
Sbjct: 31809 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 31868

Query: 749   GESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVY 803
               +  L  +V G+P+P + W +  K + A   K       G  H + I+      D  VY
Sbjct: 31869 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL-IIASVTDDDATVY 31927

Query: 804   TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
              ++A N  G    +A + VE P + +   P  +     +       + +    +  P P 
Sbjct: 31928 QVRATNQGGSVSGTASLEVEVPAKIHL--PKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 31985

Query: 864   ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             ITW +  ++I  +             LV  N     D+G Y   A N  G
Sbjct: 31986 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 32035



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 54/226 (23%), Positives = 96/226 (42%), Gaps = 22/226 (9%)

Query: 705   EGTYTVVAVNREGEA--SLP---IVLKIKTGEKEPPQVIEPLKSMIV-------RQGESV 752
             E ++ + A+N+ G +  S P   +  ++       P+VI+  KS +          G S 
Sbjct: 20088 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 20147

Query: 753   ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             I+   V     P   W + N     +P +     ++ T L+ K           A N   
Sbjct: 20148 IIGYFVEACKLPGDKWVRCNTAPHQIPQEE----YTATGLEEKAQYQFRAIARTAVNISP 20203

Query: 813   IAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNN 870
              +E S  +T+     EN  P + ++   +  +TVK    + L A V   P+P+++W ++ 
Sbjct: 20204 PSEPSDPVTI---LAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDG 20260

Query: 871   EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              ++ P+E I          L + +V+ + DSGDY   A NS+G  S
Sbjct: 20261 TLLKPAEGIKMAMQRNLCTLELFSVNRK-DSGDYTITAENSSGSKS 20305



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 3/118 (2%)

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            + E  E +A   A+  V    +E  +P + +   + + V E  T +   RVT  P P + 
Sbjct: 1815 RIEELERMAHEGALTGVTTDQKEKQKPDIVLYP-EPVRVLEGETARFRCRVTGYPQPKVN 1873

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            WY N ++I  S+     +DG +  L I +  S  D+G+ K  A N  G   H  ++ I
Sbjct: 1874 WYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKS-YDTGEVKVTAENPEGVIEHKVKLEI 1929



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 13/129 (10%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQGES 751
             + N+ + Q   + V AVN  GE+   + L +   + E P  I+   S+      V+ GE 
Sbjct: 16283 VENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEP 16342

Query: 752   VILSAQVVGNPRPTITWCKN----NKPVKALP-TKSD-GDTHSITILK-PKKVK-DEGVY 803
             V + A V G P P I W KN     KP  AL  TK +   + + T L  PK V+ D+G Y
Sbjct: 16343 VHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTY 16402

Query: 804   TLKAENSEG 812
             T+ A N  G
Sbjct: 16403 TVTASNRLG 16411



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 6/124 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRN 859
             + +KAEN  G+      I +E   +E   PP   L +   + + VK   T++  A +   
Sbjct: 18407 FRVKAENIVGLGLPDTTIPIE--CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGV 18464

Query: 860   PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             PVP+  W  +   I   E  T   D  +  L I N     D+G+Y+   SN+AG  +   
Sbjct: 18465 PVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR-DTGEYQITVSNAAGSKTVAV 18523

Query: 920   RVTI 923
              +T+
Sbjct: 18524 HLTV 18527



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 34/130 (26%), Positives = 66/130 (50%), Gaps = 11/130 (8%)

Query: 691   YCSVLKITNVKKFQEGTYTVVA---VNREGEASLPIVLKIKTGEKEPPQVIEPLKS---M 744
             Y  V ++T  ++++   +   A   V+   E++ PI++K    + EPP+V+  +K    +
Sbjct: 26670 YFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVK---DDVEPPRVMMDVKFRDVI 26726

Query: 745   IVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGV 802
             +V+ GE + ++A + G P P I+W K+   +  +A       D H++  +K    +D G 
Sbjct: 26727 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 26786

Query: 803   YTLKAENSEG 812
             Y L  +N  G
Sbjct: 26787 YVLTLKNVAG 26796



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 14/198 (7%)

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529
            K+     +++P + + +++ T     D        G P P+  WY++G K++ +   Y  
Sbjct: 2068 KIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWY 2127

Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE--DIKQKH 1584
               +N                    A N  GE  +   + +Q K +IT + E  D+  K 
Sbjct: 2128 WPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE 2187

Query: 1585 KVGDEWLVTAVIEGIPP-PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            K   + + T   E   P  +V WYK+G ++    +Y + +  K   + I  +  S +  Y
Sbjct: 2188 K---DTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2244

Query: 1644 T---IEASNTAGTSSVEV 1658
            +   +E  N   T+ + V
Sbjct: 2245 SCVLVEDENVKTTAKLIV 2262



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 1/102 (0%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            TS +    PIF +K  P  T  G+ V  EC+++G P   ++W++    ++  + +++   
Sbjct: 8318 TSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MS 8376

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            ++ + ++ I  V   D G + C A N  G  +    + ++AP
Sbjct: 8377 ENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAP 8418



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 54/243 (22%), Positives = 85/243 (34%), Gaps = 21/243 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561
            +E+   P F +KL            FEC++   G P   + W      ++ +   +M  +
Sbjct: 1697 KEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI-N 1755

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGS---------- 609
            +    +L     +  D+G  TC A N  G   ++  LIV  E  L +             
Sbjct: 1756 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1815

Query: 610  -EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
             E                D  E   P     P+   V EG      CR+   P+P + W 
Sbjct: 1816 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1875

Query: 669  FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
              G+ I   +   V  +  +H     L I + K +  G   V A N EG     + L+I+
Sbjct: 1876 LNGQLIRKSKRFRVRYDG-IH----YLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ 1930

Query: 729  TGE 731
              E
Sbjct: 1931 QRE 1933



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+ V  +  V G P P ++W +   ++KP++  +M     N+ TL +  V  +D+G +T 
Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVNRKDSGDYTI 20295

Query: 584   VAKNAAGFASSTTELIV 600
              A+N++G  S+T +L V
Sbjct: 20296 TAENSSGSKSATIKLKV 20312



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            +Q++ P F +KL       GS++  EC+V G       WF+    I  S  +++   + +
Sbjct: 6159 DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERS 6218

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            V +L +  +  ED   +TC   N AG  + +  L V+ P S
Sbjct: 6219 V-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPS 6258



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P PE  W+ +G ++ ND  + +  KE  T  + I     S S ++T+ A N AG S
Sbjct: 1480 VVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRS 1539

Query: 1655 SVEVTLKV 1662
            S+ V L V
Sbjct: 1540 SISVILTV 1547



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 9/158 (5%)

Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEV 1283
            W+   + ++ D     +I +   ++LII   T  D  E+T V  +    +     L VE 
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549

Query: 1284 VEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            VE    P  V+  +   IK GS + + V     P P+  W+ NS II   K+ K  I+  
Sbjct: 1550 VEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGT 1609

Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               A+L I    + D+  Y     N  G       V +
Sbjct: 1610 KGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568
            P FV+KL    T  G  V+    VEG+    + W +    +I+ S++ ++ + D N+ATL
Sbjct: 7478 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFID-NIATL 7536

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             +      ++G + C  KN AG    +  L V  P
Sbjct: 7537 QLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 7571



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 47/207 (22%), Positives = 87/207 (42%), Gaps = 17/207 (8%)

Query: 697   ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGES 751
             +T++ +  E  + V+A N  G    A +P  +K+    + P   ++    + + VRQG  
Sbjct: 31021 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGV 31080

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + L+  + G P P   W K  + +      +  +TH+  ++K     D G Y L  EN  
Sbjct: 31081 IRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKC 31140

Query: 812   GIAETSAVITVEEPTEENA-EPPLFINRFQEITVK-------EKGTIKLVARV-TRNPVP 862
             G  + +  I V      N+ E PL  +  Q  +V+       + G   ++  +  R  VP
Sbjct: 31141 G--KKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVP 31198

Query: 863   SITWYRNNEIISPSETITQNFDGENIE 889
                WY  +  +  +  + +    EN+E
Sbjct: 31199 KAAWYTIDSRVRGTSLVVKGLK-ENVE 31224



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 3/124 (2%)

Query: 477  ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
            E++  +Y+ + LN+   K     K T  +++ AP+   K+ P     G   +F C+++  
Sbjct: 4352 EDHQGEYVCEALNDS-GKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 4409

Query: 537  PRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596
            P  +  WF+    I  S D         +++L I      D G +TC A N  G  S T 
Sbjct: 4410 PNVRFQWFKAGREIYES-DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4468

Query: 597  ELIV 600
             L V
Sbjct: 4469 TLTV 4472



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 39/124 (31%), Positives = 57/124 (45%), Gaps = 6/124 (4%)

Query: 704   QEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQGESVILSAQVVG 760
             +E    V AVN  G  S P  +      K+P   P +      +IV +GE + +      
Sbjct: 15281 KEYVLRVRAVNAIG-VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRA 15339

Query: 761   NPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVK-DEGVYTLKAENSEGIAETSA 818
              P PT++W K+ K VKA    +  + H S  +  PK V+ D G+YT+  EN  G A  S 
Sbjct: 15340 VPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASI 15399

Query: 819   VITV 822
              + V
Sbjct: 15400 NVKV 15403



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%)

Query: 803   YTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
             + +KA N   EG     A   + +      E  L +     ITV+   TI+++ARV   P
Sbjct: 18804 FRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRP 18863

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
              P ITW +  +++   + +    D   +EL I       D G Y   A NS+G +   A 
Sbjct: 18864 EPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEA-VRADHGKYIISAKNSSGHAQGSAI 18922

Query: 921   VTIDVEKVTFVKHLQKSYETEEGKTVILE 949
             V + +++    ++L+ +  T+E  T+  E
Sbjct: 18923 VNV-LDRPGPCQNLKVTNVTKENCTISWE 18950



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 5/122 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
             + + A N+ G++       V E  E+   P + +   ++IT+K    +++ A V   P P
Sbjct: 19798 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP--EQITIKAGKKLRIEAHVYGKPHP 19855

Query: 863   SITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             +  W +  +E+++ S       D  +I L+I +V  + DSG Y   A NS+G  +   +V
Sbjct: 19856 TCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVTRK-DSGYYSLTAENSSGTDTQKIKV 19913

Query: 922   TI 923
              +
Sbjct: 19914 VV 19915



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 5/116 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNP 860
             + + A N +G++E S  I   EP E    P L +  +  + +T++   +++L+  V+  P
Sbjct: 30342 FRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRP 30401

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              P ITW +    ++    I      E+  L+I +  +  D+G Y   A N +GK S
Sbjct: 30402 PPVITWSKQGIDLASRAIIDTT---ESYSLLIVDKVNRYDAGKYTIEAENQSGKKS 30454



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 28/121 (23%), Positives = 52/121 (42%)

Query: 702   KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
             KF+     +  +   GE +  I +K +    +          ++V  G  + + A V G 
Sbjct: 17419 KFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 17478

Query: 762   PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             P PT+TW  N + +    T       S  ++K  +   +GVY+L A+N  G  + + ++ 
Sbjct: 17479 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 17538

Query: 822   V 822
             V
Sbjct: 17539 V 17539



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 746   VRQGESVILSAQVVGNPRPTITWCKNNKP-VKALPTKSDGDTHSITILKPKKVK-DEGVY 803
             VR G+++ + A+V G P P ITW K  K  V+        D   + +   + V+ D G Y
Sbjct: 18847 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 18906

Query: 804   TLKAENSEGIAETSAVITV 822
              + A+NS G A+ SA++ V
Sbjct: 18907 IISAKNSSGHAQGSAIVNV 18925



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 23/76 (30%), Positives = 37/76 (48%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+   +   I G P P V WY+   ++E+  ++ IT +   + + I+E     S ++T  
Sbjct: 957  GESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 1016

Query: 1647 ASNTAGTSSVEVTLKV 1662
            A N AGT S    L V
Sbjct: 1017 AVNEAGTVSTSCYLAV 1032



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 6/182 (3%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787
            EK+ P ++   + + V +GE+     +V G P+P + W  N + +   K    + DG  H
Sbjct: 1837 EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG-IH 1895

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
             + I+  K   D G   + AEN EG+ E    + +++  +  +          E  V E 
Sbjct: 1896 YLDIVDCKSY-DTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEP 1954

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
            G ++   +    PV + T  +    +  +E IT     E  E + +      + G Y+ +
Sbjct: 1955 GKLQFEVQKVDRPVDT-TETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAI 2013

Query: 908  AS 909
             +
Sbjct: 2014 TA 2015



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 1/102 (0%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T+ E   +P F  K        G +  FEC V G    +ITW +    I+P  ++ +   
Sbjct: 7190 TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC- 7248

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              N   L I +V   D+G +TC A N  G    + +L V+ P
Sbjct: 7249 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 14/179 (7%)

Query: 747   RQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
             + G S I+   V   P  T  W + N++P+K L  K +        + P K   E V  +
Sbjct: 15237 KNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG------VVPDK---EYVLRV 15287

Query: 806   KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864
             +A N+ G++E S +       + + +P + +     I ++ EK +I +  R    PVP++
Sbjct: 15288 RAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAV--PVPTV 15345

Query: 865   TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             +W+++ + +  S+ +T   D  +  L +       D+G Y     N  G ++    V +
Sbjct: 15346 SWHKDGKEVKASDRLTMKNDHISAHLEVPK-SVRADAGIYTITLENKLGSATASINVKV 15403



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V  G+++ L+  +   P P ++W   G  + P E I +A++ ++   C+ L++ +V +  
Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CT-LELFSVNRKD 20289

Query: 705   EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737
              G YT+ A N  G  S  I LK+      P  V
Sbjct: 20290 SGDYTITAENSSGSKSATIKLKVLDKPGPPASV 20322



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 9/99 (9%)

Query: 731   EKEPPQV-IEPL--KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDG 784
             E +PP++ ++P    +++V  GES  + A + G P PTI W K ++ +     L  KS  
Sbjct: 23464 EVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 23523

Query: 785   DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
                S+++    +V D G Y LKA+N  G  E S  + V+
Sbjct: 23524 FATSLSVKDAVRV-DSGNYILKAKNVAG--ERSVTVNVK 23559



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 520   HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
             H P G  V+    + G P P  +WF   + ++ S+   +      VA L IRE    D G
Sbjct: 30676 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIRDTG 30734

Query: 580   TFTCVAKNAAGFASSTTELIV 600
              +T   KN  G  S T ++I+
Sbjct: 30735 EYTLELKNVTGTTSETIKVII 30755



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 2/125 (1%)

Query: 799   DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
             +E  + + A+N +GI++    ++V    ++   PP F   F   TV     +K+      
Sbjct: 23042 EEYSFRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG 23100

Query: 859   NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
              P P++TW+++N  +  +  +       N  L I +   E D G Y    +NSAG++   
Sbjct: 23101 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE-DVGHYVVKLTNSAGEAIET 23159

Query: 919   ARVTI 923
               V +
Sbjct: 23160 LNVIV 23164



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 36/136 (26%), Positives = 66/136 (48%), Gaps = 13/136 (9%)

Query: 697   ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQ 748
             ++ +++  E  + V A N+ G     E  LP+++K    + EPP++     P  ++ VR 
Sbjct: 27361 VSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK---EQLEPPEIDMKNFPSHTVYVRA 27417

Query: 749   GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITI-LKPKKVKDEGVYTLK 806
             G ++ +   + G P P +T  ++  P+KA +   ++    ++TI LK     D G Y + 
Sbjct: 27418 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 27477

Query: 807   AENSEGIAETSAVITV 822
             A NS G  +    I V
Sbjct: 27478 AANSSGTTKAFINIVV 27493



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQV---IEPLKSMIVRQGE 750
             ++N+K      + V AVN  G+   PI +      K   E P++   +    S+I + GE
Sbjct: 28156 VSNLKPGVNYYFRVSAVNCAGQGE-PIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 28214

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808
              V +     G P PT+TW K+ K + +    S  +T S ++L   +V   D G Y L  E
Sbjct: 28215 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 28274

Query: 809   NSEGIAETSAV 819
             N  G  ++S V
Sbjct: 28275 NGVGEPKSSTV 28285



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 512   FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
             F + L  +   +G+T   EC+V      ++ WF+    I  S+ +++  D   V  LVI 
Sbjct: 13214 FTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADG-RVRKLVIH 13271

Query: 572   EVFPEDAGTFTCVAKN 587
             +  PED  T+TC AK+
Sbjct: 13272 DCTPEDIKTYTCDAKD 13287



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 5/114 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNP 860
             + + A N  GI E   V  V E  +    P L ++      I V   G I+++A V+  P
Sbjct: 17420 FRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKP 17479

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              P++TW  N   +    TI       +  +VI N       G Y  +A N AG+
Sbjct: 17480 PPTVTWNMNERTLPQEATIETT--AISSSMVIKNCQRS-HQGVYSLLAKNEAGE 17530



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%)

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTI 1156
            A V +   PP +++ L+N  V +G   T E  ++   +  V W+++  +I+ S   Q+T 
Sbjct: 934  APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
                 +L I +   +D+G ++C   N   T
Sbjct: 994  QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            ++  P F+ + +   T  G   +F C V G P  +  W +  A + PS ++++  D +N 
Sbjct: 4474 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKI-SDAENK 4532

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              L +  +  +D G ++C A N  G      ELI+
Sbjct: 4533 HILELSNLTIQDRGVYSCKASNKFGADICQAELII 4567



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 7/133 (5%)

Query: 795   KKVKDEGVYTLK--AENS--EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
             K++++   Y L+  A N+  EG    +  +TV EP E  A   L ++    I +    T+
Sbjct: 15991 KEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVE-LDVSVKGGIQIMAGKTL 16049

Query: 851   KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
             ++ A VT  PVP+  W +    +     +  N  G   EL+I +   + D G Y   A+N
Sbjct: 16050 RIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNV-GTKSELIIKDALRK-DHGRYVITATN 16107

Query: 911   SAGKSSHGARVTI 923
             S G     ARV +
Sbjct: 16108 SCGSKFAAARVEV 16120



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 10/148 (6%)

Query: 779   PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP---LF 835
             PT   G   ++T LK      E  + + A NSEG+ E  A +      +E  EPP   L 
Sbjct: 25982 PTGLQGKQFTVTKLKENT---EYNFRICAINSEGVGEP-ATLPGSVVAQERIEPPEIELD 26037

Query: 836   INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
              +  + + ++   T++L   +   P P + W +   I++    I          LVI NV
Sbjct: 26038 ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNV 26095

Query: 896   DSEIDSGDYKCVASNSAGKSSHGARVTI 923
              +  DSG Y     N++G  +    V +
Sbjct: 26096 -TRFDSGRYNLTLENNSGSKTAFVNVRV 26122



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 12/191 (6%)

Query: 632   IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             +PP+   K   + V+EG+++ +  ++  +P P + W FK     PD    V  ++ ++  
Sbjct: 17043 MPPSIDLKEFME-VEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLYDTHVNKL 17100

Query: 692   C----SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                    L I   ++   G YT+ AVN  G AS  + L +  G   PP  + P+K   V 
Sbjct: 17101 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV-LGRPGPP--VGPIKFESVS 17157

Query: 748   QGESVI--LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYT 804
               +  +     +  G  + T    +  +  +        +    T   PK ++  E V+ 
Sbjct: 17158 ADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFR 17217

Query: 805   LKAENSEGIAE 815
             + A+N  GI E
Sbjct: 17218 IMAQNKYGIGE 17228



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 14/153 (9%)

Query: 700   VKKFQEGT---YTVVAVNREGEASLPIVLKIKTGEKE--PPQV-IEPLKSMIVRQGESVI 753
             VK  +EG    Y V AVN  G+       K  T + E  PP + ++    + +R GE+  
Sbjct: 17705 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFA 17764

Query: 754   LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
             L+ +  G P+P ++W K+   V        K+   T ++  +K K+  D G Y +  ENS
Sbjct: 17765 LTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR-SDSGKYCVVVENS 17823

Query: 811   EGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
              G  +    + V     +   PP+    F E+T
Sbjct: 17824 TGSRKGFCQVNV----VDRPGPPVGPVSFDEVT 17852



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 12/134 (8%)

Query: 475   MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM----AP-IFVE-KLRPKHTPD-GSTV 527
             ++E  +  Y  K LN +    P   +PT E Q++    AP IF++ KL    T   G+ +
Sbjct: 14578 LEEGKWYAYRVKALNRQGASKP--SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 14635

Query: 528   QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTFTCVAK 586
             +    V G P P+ITW +   I+K  QD ++  ++    +T+ I +    D GT+   A 
Sbjct: 14636 ELPATVTGKPEPKITWTKADMILK--QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 14693

Query: 587   NAAGFASSTTELIV 600
             N  G A++  E+ V
Sbjct: 14694 NVCGRATAVVEVNV 14707



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 7/119 (5%)

Query: 709   TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSA-QVVGNPRPT 765
             T  A++   E++  I+ K +   + P  V++P     + ++ G++++L+A  ++G P P 
Sbjct: 21280 TAGAISAPSESTETIICKDEY--EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK 21337

Query: 766   ITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
              +W K  K ++   +   +   T S+  +K    KD G YT+ A N  G       +TV
Sbjct: 21338 SSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 21396



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 8/106 (7%)

Query: 712   AVNREGEASLPIVLKIKTGEKEPPQV-IEPL--KSMIVRQGESVILSAQVVGNPRPTITW 768
             A+++  +++ PI  K    E E P++ ++P    +++V  GE+  L A V G P PTI W
Sbjct: 24530 AISKPSDSTGPITAK---DEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 24586

Query: 769   CKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              + +K ++  A     + D  ++ I+K     D G Y L+A N  G
Sbjct: 24587 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 24632



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 499   EKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
             EK T+ +   ++A   + K R     +G + +F C  +G P P +TW R+  ++  S   
Sbjct: 33475 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 33534

Query: 557   QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             Q+       +T  I  V   D G ++ V +N+ G   +   L ++
Sbjct: 33535 QV-TTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 33578



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 18/66 (27%), Positives = 29/66 (43%)

Query: 1597  EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
             +G P P V W + G  L     + +TT +  S   I  ++ S    Y++   N+ G    
Sbjct: 33512 DGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEA 33571

Query: 1657  EVTLKV 1662
             E TL +
Sbjct: 33572 EFTLTI 33577



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 12/129 (9%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPV 861
             + +KA N+ G+++ SA +   +    +  P + +  F E+   E+GT + +VA++   P 
Sbjct: 17016 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEV---EEGTNVNIVAKIKGVPF 17072

Query: 862   PSITWYR-------NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             P++TW++       N E +     + +    +   LVI       D+G Y   A N+ G 
Sbjct: 17073 PTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQ-SRRSDTGLYTITAVNNLGT 17131

Query: 915   SSHGARVTI 923
             +S   R+ +
Sbjct: 17132 ASKEMRLNV 17140



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 25/120 (20%), Positives = 57/120 (47%), Gaps = 4/120 (3%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQV---IEPLKSMIVRQGESV 752
             + +++  ++  + + A+N  G     ++  ++  E+E  P      E  ++++VR G S+
Sbjct: 21662 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSI 21721

Query: 753   ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              +   + G P P +TW K+N  +K      + ++ ++ I+      D G + +  EN  G
Sbjct: 21722 RIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 21781



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 743   SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDE 800
             ++I++ GE+  L A V G P PT+ W K+ K ++  A       D  +  + K    +D 
Sbjct: 22397 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 22456

Query: 801   GVYTLKAENSEGIAE 815
             G YTL A N  G A+
Sbjct: 22457 GAYTLTATNPGGFAK 22471



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 695   LKITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             +++  + +  E  + + A+N+ G     +   PI+++ K    +    +E  K + +R G
Sbjct: 23825 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 23884

Query: 750   ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
              S+ L   + G P P + W K +  ++         + +  +L      D G YTL  EN
Sbjct: 23885 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLEN 23944

Query: 810   SEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
             S G    SA +TV     +   PP+ + +  EIT
Sbjct: 23945 SSG--TKSAFVTVR--VLDTPSPPVNL-KVTEIT 23973



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 7/135 (5%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753
             I+ +   +E  + V AVN +G +  P  L +    ++    P V  P  +  V+  E + 
Sbjct: 26282 ISGLTAGEEYVFRVAAVNEKGRSD-PRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340

Query: 754   LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSE 811
             +     G P+ T+ W K+ + +K     +   + ++T L  K+   +D G Y L   NS 
Sbjct: 26341 IDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA 26400

Query: 812   G-IAETSAVITVEEP 825
             G I     +I ++ P
Sbjct: 26401 GSITVPITIIVLDRP 26415



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 1/78 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G +++ +  V+G P P++TWF+    I+   + ++  D     +L +R+   +  G +T 
Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRDHRGVYTV 28958

Query: 584   VAKNAAGFASSTTELIVE 601
              AKNA+G A +  ++ V+
Sbjct: 28959 EAKNASGSAKAEIKVKVQ 28976



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 47/216 (21%), Positives = 86/216 (39%), Gaps = 8/216 (3%)

Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISD 1247
            +T + P+  FT  L   +++  +T  +          +V+W++   VI   T     IS 
Sbjct: 1    MTTQAPT--FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF 58

Query: 1248 VKKRT-LIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
               R  L I   T+ +   Y+    +    A ST +L V+    PP  V   +   +++G
Sbjct: 59   SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQG 118

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
            S V L V     P P  ++  +   I+     + S +    SL I +    D+G Y +  
Sbjct: 119  SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
             N+ G A     + +  +   P K     + ++ I+
Sbjct: 179  TNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQIS 214



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 4/100 (4%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PPT     K   V EG  + LEC +   P P + W  +  +I    +  +  +S +    
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI---- 997

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
            + L I        G +T  AVN  G  S    L ++  E+
Sbjct: 998  ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 8/131 (6%)

Query: 700   VKKFQEGT---YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMI-VRQGESV 752
             VK+ +EG      V AVN  GE        +   E + P  +E    +K  I +  G+++
Sbjct: 15990 VKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTL 16049

Query: 753   ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
              + A V G P PT  W K    + K      +  T S  I+K    KD G Y + A NS 
Sbjct: 16050 RIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 16109

Query: 812   GIAETSAVITV 822
             G    +A + V
Sbjct: 16110 GSKFAAARVEV 16120



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 7/133 (5%)

Query: 696   KITNVKKFQEGTYTVVAVNREG--EA-SLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGE 750
             +I+ + + QE    V A+N+ G  EA S+P  +K +   + P   +  E  K ++VR G 
Sbjct: 24908 EISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGG 24967

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
             S  +     G P P ITW +             G  ++   +      D G Y LK ENS
Sbjct: 24968 SARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENS 25027

Query: 811   EGIAETSAVITVE 823
              G    SA +TV+
Sbjct: 25028 SG--SKSAFVTVK 25038



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 50/230 (21%), Positives = 94/230 (40%), Gaps = 10/230 (4%)

Query: 702   KFQEGTYTVVA--VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI--VRQGESVILSAQ 757
             ++Q  TY + A  V++  EAS PI+ +        P+V +  +S +  +    +    ++
Sbjct: 29837 EYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSK 29896

Query: 758   VVGN--PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN--SEGI 813
             VVG    R  ++   + + +K   T    +  ++T L      +  V    A    S+G 
Sbjct: 29897 VVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGS 29956

Query: 814   AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
               T  V   +E     AE    ++    +T++    + L A V   P P I W + ++ +
Sbjct: 29957 ESTGPVTCRDEYAPPKAELDARLHG-DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL 30015

Query: 874   SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
                E ++  + G+    VI   D   DSG Y     N++G  +    V +
Sbjct: 30016 DLCEKVSLQYTGKRATAVIKFCDRS-DSGKYTLTVKNASGTKAVSVMVKV 30064



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 5/123 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNP 860
             + + A N+ G  E + V    + TE    P   ++ R+QE I V++ G I+L   +   P
Sbjct: 31032 FRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP 31091

Query: 861   VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
              P   W +  + IS    I  +    + ELVI   D   DSG Y  V  N  GK +   +
Sbjct: 31092 FPICKWTKEGQDISKRAMIATS--ETHTELVIKEADRG-DSGTYDLVLENKCGKKAVYIK 31148

Query: 921   VTI 923
             V +
Sbjct: 31149 VRV 31151



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 39/159 (24%), Positives = 63/159 (39%), Gaps = 11/159 (6%)

Query: 450   TSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEK-IDKLPVFEKPTSEEQSM 508
             T  + W    K   EE  +   + L++   Y ++  K +N   + K      P   ++  
Sbjct: 16985 TKKEAWRQCNKRDVEELQFT-VEDLVEGGEY-EFRVKAVNAAGVSKPSATVGPCDCQRPD 17042

Query: 509   APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD------ 562
              P  ++        +G+ V    +++G P P +TWF+     KP     + YD       
Sbjct: 17043 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPP-KKPDNKEPVLYDTHVNKLV 17101

Query: 563   -DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              D+  TLVI +    D G +T  A N  G AS    L V
Sbjct: 17102 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 17140



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 742   KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--D 799
             K++I+R G ++ L   V G P P ITW K N  ++         T   T L+ + V   D
Sbjct: 20628 KTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 20687

Query: 800   EGVYTLKAENSEGIAETSAVITV 822
              G Y L  ENS G  E + V+ V
Sbjct: 20688 AGKYILTLENSCGKKEYTIVVKV 20710



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/139 (20%), Positives = 61/139 (43%), Gaps = 6/139 (4%)

Query: 787   HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
             H++T L      ++ ++ ++A+N +G++E    +T     +    P + ++   + T+  
Sbjct: 30621 HTVTSLNEG---EQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 30677

Query: 847   KG--TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
                  ++LV  +   P P+ +W+     +  SE +T     +  +L I       D+G+Y
Sbjct: 30678 PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR-DTGEY 30736

Query: 905   KCVASNSAGKSSHGARVTI 923
                  N  G +S   +V I
Sbjct: 30737 TLELKNVTGTTSETIKVII 30755



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
             + ++AEN+ GI+E S      +  +    P + +    E  VK    I L A ++ +P P
Sbjct: 15579 FRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE--VKRGDEIALDASISGSPYP 15636

Query: 863   SITWYRNNEIISPSE 877
             +ITW ++  +I P E
Sbjct: 15637 TITWIKDENVIVPEE 15651



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 5/131 (3%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEK--EPPQVIEP--LKSMIVRQGES 751
             +T+++  +E  + V A+N  G+  S  +   IK  ++   P   I+    ++ +VR G S
Sbjct: 29242 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGAS 29301

Query: 752   VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             + L     G P PT  W K +  +         D+ S   ++     D G YTL  EN+ 
Sbjct: 29302 IRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNS 29361

Query: 812   GIAETSAVITV 822
             G    +  + V
Sbjct: 29362 GSKSITFTVKV 29372



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
            +SN DI     +GD   ++  + GIP P++ W+ NG  L    +Y          + I  
Sbjct: 3509 VSNADIS----MGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3564

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
             K     +YT  ASN  G +     LK+  K
Sbjct: 3565 TKLEDEGEYTCMASNDYGKTICSAYLKINSK 3595



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F +K  P     GS V  +C++ G P  ++ W +    ++ S+ F++     +  +L 
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFD-TSLH 7443

Query: 570  IREVFPEDAGTFTCVAKNAAG 590
            I  +   D G + C A N  G
Sbjct: 7444 ILNLEASDVGEYHCKATNEVG 7464



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 1/72 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G T++   +V+G P P ITW ++  ++   +   +  D   V  L I+E    D G +  
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADHGKYII 18908

Query: 584   VAKNAAGFASST 595
              AKN++G A  +
Sbjct: 18909 SAKNSSGHAQGS 18920



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582
             G  ++ E  V G PRP I+W +    +K  Q  ++  ++   +T++ I+E   +D G +T
Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLK--QTTRVNVEETATSTVLHIKEGNKDDFGKYT 25310

Query: 583   CVAKNAAGFASSTTELIV 600
               A N+AG A+    +IV
Sbjct: 25311 VTATNSAGTATENLSVIV 25328



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 9/125 (7%)

Query: 705   EGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQ 757
             E  + V +VN+ G     ++S P + K +  E+EP   I  E  K++IV+ G S  ++  
Sbjct: 27079 EYVFRVKSVNKVGASDPSDSSDPQIAKER--EEEPLFDIDSEMRKTLIVKAGASFTMTVP 27136

Query: 758   VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
               G P P + W K +  ++        D+ +   ++     D G YTL  +N    A  +
Sbjct: 27137 FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 27196

Query: 818   AVITV 822
              V+ V
Sbjct: 27197 LVVKV 27201



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 11/142 (7%)

Query: 695   LKITNVKKFQEGTYTVVAVNREGEASL----PIVLK--IKTGEKEPPQVIEPLKSMIVRQ 748
             ++++ +K+     + V A N +G +      PI +K  I T E +   +  P   + VR 
Sbjct: 28447 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDI--PGAQVTVRI 28504

Query: 749   GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLK 806
             G +V L     G P+P+I+W K+  P+K         T +   L  K  K E  G YT+ 
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564

Query: 807   AENSE-GIAETSAVITVEEPTE 827
              +N+   IA    VIT+  P++
Sbjct: 28565 LDNAVCRIAVPITVITLGPPSK 28586



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 6/127 (4%)

Query: 802   VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNP 860
             +Y  + +      E+  V T E   +E+ + P+   +   + TVK   TI+L A V   P
Sbjct: 19097 IYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKP 19156

Query: 861   VPSITWYRNNEI--ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
              P + W ++ +   ++ S  +  +   ++ +  +T      D G Y   A+N+AG  S  
Sbjct: 19157 FPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA-KRSDGGKYVVTATNTAG--SFV 19213

Query: 919   ARVTIDV 925
             A  T++V
Sbjct: 19214 AYATVNV 19220



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G  ++ E  + G P+P ITW +    +K +    +  D  ++ TL I+E   +D G +  
Sbjct: 24171 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGGQYGI 24229

Query: 584   VAKNAAGFASSTTELI 599
                N  G  +++ E++
Sbjct: 24230 TVANVVGQKTASIEIV 24245



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 523   DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTF 581
             +G  +   C   G P P++TW      I   +  + + ++ D++ TL+I +V  +D G +
Sbjct: 34269 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 34328

Query: 582   TCVAKNAAGFASSTTELIVEA 602
             T    N  G  S+T  + + +
Sbjct: 34329 TLSLGNEFGSDSATVNIHIRS 34349



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 13/200 (6%)

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            Y V     S + E  E     +E  +  P +  PL++  T   +     C   G    KV
Sbjct: 3317 YGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKV 3375

Query: 1514 TWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            +WY   KK+K ++      +E+                Y  +A N  G+V ++  + ++ 
Sbjct: 3376 SWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435

Query: 1570 KPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI------ 1621
               I      ++I+ + K      ++A  EG+   E+   K    LE   E  +      
Sbjct: 3436 PESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFD 3495

Query: 1622 TTKEKTSVIRIKELKRSHSS 1641
            + KE T  I IKE+  +  S
Sbjct: 3496 SEKEGTGPIFIKEVSNADIS 3515



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 6/106 (5%)

Query: 632   IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             I P+         +  G D+ +E  ++  P P+I+W+  GE +     ++V    +    
Sbjct: 25237 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV----EETAT 25292

Query: 692   CSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPP 735
              +VL I    K   G YTV A N  G A  +L +++  K G    P
Sbjct: 25293 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP 25338



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 747   RQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYT 804
             R G SV L A + G P PTI W K++K ++  AL    +    +  ++K     + G Y 
Sbjct: 27812 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 27871

Query: 805   LKAENSEGIAETSAVITVE 823
             LK  N+ G A  SA I V+
Sbjct: 27872 LKLRNAMGSA--SATIRVQ 27888



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 53/244 (21%), Positives = 91/244 (37%), Gaps = 20/244 (8%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXX 1538
            P  E+ L+++T +  +   +TC F  VP  K  W+R+G+ LK     K   E++      
Sbjct: 9672 PAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTI 9730

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE- 1597
                          + D   +ETS  + I+ +P+         Q   V +    T   E 
Sbjct: 9731 ADVRAEDQGQYTCKYED---LETSAELRIEAEPIQFTKRI---QNIVVSEHQSATFECEV 9784

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI--------EASN 1649
                  V WYK   +L   ++YN     +   + I  +       Y++        EA +
Sbjct: 9785 SFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARS 9844

Query: 1650 TAGTSSVEVTLKVYDKPSK-PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
            TA        +K+  KP   P+  V +  +   +V  E  PP+    + L     E+ +P
Sbjct: 9845 TAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKP 9904

Query: 1709 DNNR 1712
               R
Sbjct: 9905 PPKR 9908



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 14/134 (10%)

Query: 1604  VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV----- 1658
             V+W+KN  KL   +   I+++ KT  + +KE+     S+   +    + T+ ++V     
Sbjct: 12531 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADP 12590

Query: 1659  --TLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGG--LELTKYAIEKHEPDNNRW 1713
               T+K++DK +  +  + ++ E+S++ V ++W     DG   +   KY+I+         
Sbjct: 12591 YFTVKLHDKTAVEKDEITLKCEVSKD-VPVKW---FKDGEEIVPSPKYSIKADGLRRILK 12646

Query: 1714  IKVADVDRDVETYC 1727
             IK AD+    E  C
Sbjct: 12647 IKKADLKDKGEYVC 12660



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 4/100 (4%)

Query: 504   EEQSMAPIFVEKLRPKHTP---DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
             +EQ   P    K  P HT     GS ++ +  + G P P++T  R    +K +  F    
Sbjct: 27395 KEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEI 27454

Query: 561   DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
               +N+ T+ ++E    DAG +   A N++G   +   ++V
Sbjct: 27455 TAENL-TINLKESVTADAGRYEITAANSSGTTKAFINIVV 27493



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G  V  E   +G P+P I+W +    +K S +F  +   +N  TL I+    E  G +T 
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKES-EFVRFSKTENKITLSIKNAKKEHGGKYTV 28563

Query: 584   VAKNA 588
             +  NA
Sbjct: 28564 ILDNA 28568



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 14/101 (13%)

Query: 1201  RLPEFILVPANTDAYL--------TVEIPDETLDVTWYKKKSVI---EDTEKFTLISDVK 1249
             R PEF L   N  AY+        T+ +  E   VTWYK    I   ++ +K+T  SD  
Sbjct: 32615 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKG 32673

Query: 1250  KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP 1288
                L I   T DD  EYT V  +   + + K K+ V   PP
Sbjct: 32674 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 32714



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 9/142 (6%)

Query: 808  ENSEGIAETSAVITVEEPTEENAEP-----PLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            E    +     V+T    TEE A P     P FI +     + E G++    +V  NP P
Sbjct: 1052 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKP 1111

Query: 863  SITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
             + W ++   ++      ++ N      +LVI+   ++ D+G+Y  V  N  G++S  A 
Sbjct: 1112 HVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFAD-DAGEYTIVVRNKHGETSASAS 1170

Query: 921  VTIDVEKVTFVKHLQKS-YETE 941
            +  + +    +K  Q+  Y+T+
Sbjct: 1171 LLEEADYELLMKSQQEMLYQTQ 1192



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P++ WYK+G ++++ + Y +   ++  + +RI  +       YT  ASN  G +
Sbjct: 1314 MSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1373

Query: 1655 SVEVTLKVYDKPSKPEG 1671
                + K+Y +P+ P G
Sbjct: 1374 I--CSGKLYVEPAAPLG 1388



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 8/123 (6%)

Query: 697   ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGE-KEPPQV---IEPLKSMIVRQGE 750
             +T++ + QE  + V A N+ G    P  LK  IK  E  EPP++       K +IVR G 
Sbjct: 19491 VTSLDENQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGC 19549

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVKDEGVYTLKAEN 809
              + L A V G P P +TW K          + D  DT +  ++      D G Y+L   N
Sbjct: 19550 PIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVN 19609

Query: 810   SEG 812
               G
Sbjct: 19610 PAG 19612



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 839   FQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
             + E+     GT +KL A ++  P P+I WY++++ +  +  +      +   ++I + D 
Sbjct: 27805 YTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDAD- 27863

Query: 898   EIDSGDYKCVASNSAGKSSHGARVTI 923
              ++SG Y+    N+ G +S   RV I
Sbjct: 27864 RLNSGCYELKLRNAMGSASATIRVQI 27889



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/129 (22%), Positives = 54/129 (41%), Gaps = 4/129 (3%)

Query: 796   KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVA 854
             + K++  + + A N  G+ E + +  VE    E A    L     + + V+   +I++  
Sbjct: 21666 QTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFV 21725

Query: 855   RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              +   P P +TW ++N  +     I      E+  L+I    +  D+G +     N AGK
Sbjct: 21726 PIKGRPAPEVTWTKDNINLKNRANIENT---ESFTLLIIPECNRYDTGKFVMTIENPAGK 21782

Query: 915   SSHGARVTI 923
              S    V +
Sbjct: 21783 KSGFVNVRV 21791



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 56/251 (22%), Positives = 103/251 (41%), Gaps = 28/251 (11%)

Query: 698   TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
             T   K  + TY V  ++   E    ++ + + G  EP +  EP+K+          L+  
Sbjct: 21843 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDS-LNIM 21901

Query: 758   VVGNPRPTITWCKNNKP---------VKALPTKSDGDTHSITI------LKPKKVKDEGV 802
              +     ++ W K             ++A    SD  TH  T+      ++     +E  
Sbjct: 21902 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYT 21961

Query: 803   YTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINR-FQEITVKEKG-TIKLVARVTR 858
             + + A NS G +    S  + V+E T     P L +   +Q++ + + G  IK+   V  
Sbjct: 21962 FQVMAVNSAGRSAPRESRPVIVKEQT---MLPELDLRGIYQKLVIAKAGDNIKVEIPVLG 22018

Query: 859   NPVPSITWYRNNEIISPSETITQNFDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
              P P++TW + ++I+  ++ +  NF+      ++  N     DSG Y   A N  G+   
Sbjct: 22019 RPKPTVTWKKGDQILKQTQRV--NFETTATSTILNINECVRSDSGPYPLTARNIVGEV-- 22074

Query: 918   GARVTIDVEKV 928
             G  +TI V  +
Sbjct: 22075 GDVITIQVHDI 22085



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 807   AENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNPVPS 863
             A NSEG+ E  A++      E+   PP   L  +  + +T++   T++L   +   P P 
Sbjct: 22760 AMNSEGLGEP-ALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE 22818

Query: 864   ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             + W R++       +I          L++ NV +  DSG Y     NS+G  S    V +
Sbjct: 22819 VKWARDHGESLDKASIEST--SSYTLLIVGNV-NRFDSGKYILTVENSSGSKSAFVNVRV 22875



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 8/145 (5%)

Query: 784   GDTHSITILKPKKV-KDEGVYTLKAENSEGIAET----SAVITVEEPTEENAEPPLFINR 838
             G T  +T    + V K E  + +KA+N  G +E     S+VI  E   E  A+     N 
Sbjct: 29523 GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITN- 29581

Query: 839   FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
              Q IT K      +   ++  P P +TW      +  ++ ++     +   L + +    
Sbjct: 29582 -QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKD-SMR 29639

Query: 899   IDSGDYKCVASNSAGKSSHGARVTI 923
              DSG Y     N+AG  +    V +
Sbjct: 29640 GDSGRYFLTLENTAGVKTFSVTVVV 29664



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%)

Query: 510   PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
             P  +E +   H   G  V  +    G P P ITW +   +I  +  +Q+       + + 
Sbjct: 31955 PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVF 32014

Query: 570   IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMT 612
                V  +DAG +   AKN  G    T EL + + P    G +++
Sbjct: 32015 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVS 32058



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 39/181 (21%), Positives = 75/181 (41%), Gaps = 12/181 (6%)

Query: 1507 GVPQPKVTWYRDGKKL---KTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G P P+  W+ DG+++    T K     +                 +  +A N  G    
Sbjct: 1482 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1541

Query: 1562 SCVVGIQ--QKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617
            S ++ ++  +  V  +  E +K  + K G +  +     G P P+++W KN + +   K 
Sbjct: 1542 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1601

Query: 1618 -EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVI 1674
             +  I   +  + ++I       S+ YT  A N AG  T+  +V ++V     +PE  +I
Sbjct: 1602 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1661

Query: 1675 M 1675
            +
Sbjct: 1662 I 1662



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 9/97 (9%)

Query: 735   PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSI--- 789
             P  I+  + M V +G +V + A++ G P PT+TW K    KP    P   D   + +   
Sbjct: 17044 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 17103

Query: 790   ---TILKPK-KVKDEGVYTLKAENSEGIAETSAVITV 822
                T++ P+ +  D G+YT+ A N+ G A     + V
Sbjct: 17104 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 17140



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 13/181 (7%)

Query: 640   PKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
             P AQ  V  G ++ LE      P+P I+WL  G  +   E +  +   +       L I 
Sbjct: 28496 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK----ITLSIK 28551

Query: 699   NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
             N KK   G YTV+  N     ++PI + I  G    P+   P++   ++  +SVILS  V
Sbjct: 28552 NAKKEHGGKYTVILDNAVCRIAVPITV-ITLGPPSKPK--GPIRFDEIK-ADSVILSWDV 28607

Query: 759   VGNPRPTITWCKNNKPVKALPTKSDGDTHSI---TILKPKKVKD-EGVYTLKAENSEGIA 814
               +       C + +  +   T       S+   T   P  VKD E  + ++AEN  G++
Sbjct: 28608 PEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVS 28667

Query: 815   E 815
             +
Sbjct: 28668 Q 28668



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%)

Query: 1592  VTAVIEG--IPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEAS 1648
             +T V+E   +   EV WYK+G KL+ +  +    + + T  ++I  L  S   +Y  E S
Sbjct: 33662 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 33721

Query: 1649  NTAGTSSVEV 1658
                GTS   +
Sbjct: 33722 GEGGTSKTNL 33731



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G+TV+F   + G P P   W    + IK  + + +  D+ + + L I+     D G +  
Sbjct: 18452 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-SVLTIKNCLRRDTGEYQI 18510

Query: 584   VAKNAAGFASSTTELIV 600
                NAAG  +    L V
Sbjct: 18511 TVSNAAGSKTVAVHLTV 18527



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 32/156 (20%), Positives = 69/156 (44%), Gaps = 10/156 (6%)

Query: 673   EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
             + + +EN    +   + +  S   +T  K++   T+ V A N  GE +   +  +   + 
Sbjct: 20848 DFLTEENKWQRVMKSLSLQYSAKDLTEGKEY---TFRVSAENENGEGTPSEITVVARDDV 20904

Query: 733   EPPQV-IEPLKSM--IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
               P + ++ L  +  + ++  +  L   + G P P+++W K   P+ A  T+   ++ ++
Sbjct: 20905 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL-ATDTRVSVESSAV 20963

Query: 790   T---ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
                 I+   +  D G YT+  +N  G  E +  I V
Sbjct: 20964 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20999



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/116 (20%), Positives = 46/116 (39%), Gaps = 5/116 (4%)

Query: 800   EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT--VKEKGTIKLVARVT 857
             E  + + AEN  G    S +  V    ++   P L +    ++    KE    +L   + 
Sbjct: 20877 EYTFRVSAENENGEGTPSEITVVAR--DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIK 20934

Query: 858   RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
               P PS++W +  + ++    ++      N  L++ +     D+G Y     N AG
Sbjct: 20935 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS-DAGKYTITLKNVAG 20989



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 9/131 (6%)

Query: 798   KDEGVYTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
             K E  + + A N  G+ E + V   I VEE  E   +  L +   + I ++  G+++L  
Sbjct: 23833 KHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA-PDIDLDLELRKIINIRAGGSLRLFV 23891

Query: 855   RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              +   P P + W + +  I  +  I  +       LV+ NV +  DSG Y     NS+G 
Sbjct: 23892 PIKGRPTPEVKWGKVDGEIRDAAII--DVTSSFTSLVLDNV-NRYDSGKYTLTLENSSGT 23948

Query: 915   SSHGARVTIDV 925
              S  A VT+ V
Sbjct: 23949 KS--AFVTVRV 23957



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 1/90 (1%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P IV Y    R+  G           +PQP   W +N ++I+K K  +   D     L I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG-IHYLDI 1899

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               ++ D G  K+  EN  G  + ++ + I
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 9/109 (8%)

Query: 509  APIFVEKLRPKHT------PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            A +FVE L    T      P+  T  FEC+V  +  P + W +    I+ S+ F++    
Sbjct: 2875 AKLFVETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-Q 2932

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASST-TELIVEAPLSDHGSE 610
              +  L+I     ED+  +T V  N    A+ T T +++ + L D  +E
Sbjct: 2933 GKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAE 2981



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G  ++ E  V G P P   W +    +  S    ++  D + + L+I++V  +D+G ++ 
Sbjct: 19840 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSS-SILIIKDVTRKDSGYYSL 19898

Query: 584   VAKNAAGFASSTTELIV-EAP 603
              A+N++G  +   +++V +AP
Sbjct: 19899 TAENSSGTDTQKIKVVVMDAP 19919



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 5/125 (4%)

Query: 803   YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI---NRFQEITVKEKGTIKLVA-RVTR 858
             + ++A+N+ G     +  T     ++  E P  +        +T+K   TI L A  +  
Sbjct: 21273 FRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 21332

Query: 859   NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
              P+P  +W +  + I PS+ ITQ        ++     +  D+G+Y   A+N  G     
Sbjct: 21333 KPLPKSSWSKAGKDIRPSD-ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 21391

Query: 919   ARVTI 923
              +VT+
Sbjct: 21392 VKVTV 21396



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582
             G  ++ E  V G P+P +TW +   I+K +Q  ++ ++    +T++ I E    D+G + 
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 22064

Query: 583   CVAKNAAG 590
               A+N  G
Sbjct: 22065 LTARNIVG 22072



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 4/88 (4%)

Query: 838   RFQEITVKEKG-TIKLVARVTRNPVPSITWYR-NNEIISPSETITQNFDGENIELVITNV 895
             +F++  V   G T +L A V   P+P+I W R + EI   +    +N D +   L+I   
Sbjct: 24557 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK--ALLIVKD 24614

Query: 896   DSEIDSGDYKCVASNSAGKSSHGARVTI 923
                ID G Y   ASN AG  S    V +
Sbjct: 24615 AIRIDGGQYILRASNVAGSKSFPVNVKV 24642



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G T + E  V G P P I W R    I+ S   ++  + D  A L++++    D G +  
Sbjct: 24567 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI-KNTDFKALLIVKDAIRIDGGQYIL 24625

Query: 584   VAKNAAGFAS 593
              A N AG  S
Sbjct: 24626 RASNVAGSKS 24635



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 9/141 (6%)

Query: 789   ITILKPKKVKDEGVYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITV 844
             +T  +  K+ +   Y ++  A N  G+ E ++V    +P ++   P L ++    + I V
Sbjct: 24904 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 24963

Query: 845   KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
             +  G+ ++       P P ITW R     +    I +  +    +L I N D   D+G Y
Sbjct: 24964 RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVN--YTQLSIDNCDRN-DAGKY 25020

Query: 905   KCVASNSAGKSSHGARVTIDV 925
                  NS+G  S  A VT+ V
Sbjct: 25021 ILKLENSSGSKS--AFVTVKV 25039



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 13/125 (10%)

Query: 697   ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGE 750
             +T +K+  E  + + A+N EG    A+LP  + +     EPP++    +  K +++R   
Sbjct: 25992 VTKLKENTEYNFRICAINSEGVGEPATLPGSV-VAQERIEPPEIELDADLRKVVVLRASA 26050

Query: 751   SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVK--DEGVYTLKA 807
             ++ L   + G P P + W    K    L  ++  + T S T+L    V   D G Y L  
Sbjct: 26051 TLRLFVTIKGRPEPEVKW---EKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 26107

Query: 808   ENSEG 812
             EN+ G
Sbjct: 26108 ENNSG 26112



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 1592  VTAVIEGIPPPEVIWYKNGNKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
             V     G P PEV W   G K+ + ++  ++I   +  + + I ++++     YT+   N
Sbjct: 34275 VACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGN 34334

Query: 1650  TAGTSSVEVTLKV 1662
               G+ S  V + +
Sbjct: 34335 EFGSDSATVNIHI 34347



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 15/50 (30%), Positives = 24/50 (48%)

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            I E++      +  +KN        +   C   G P PK+ WY+DGK++K
Sbjct: 1283 ISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK 1332



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%)

Query: 524   GSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDD----DNVATLVIREVFPEDA 578
             G  V     V G P P+I W + +T I KP+   Q+  ++    +    L I +   ED 
Sbjct: 16340 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 16399

Query: 579   GTFTCVAKNAAG 590
             GT+T  A N  G
Sbjct: 16400 GTYTVTASNRLG 16411



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 56/273 (20%), Positives = 103/273 (37%), Gaps = 14/273 (5%)

Query: 150   RVTLEKSDLFDSQEDESKPDVSQP--PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEV-- 205
             ++T E+  L    + E+ P    P  P+  + E K      +  E+P AK +E    V  
Sbjct: 10569 QITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVK 10628

Query: 206   PEKINVPDDKETSQTPTSFN-KRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXX 264
              EK+++   K   Q          K     +E + + V   +  E  +   +        
Sbjct: 10629 EEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEP 10688

Query: 265   XXXXXXETSLVKLPKFQLKSRIKYITS-WPPESIKPLISYMGSIKQNGILSRNIKEAAKV 323
                        +    + +   +YIT    P  +KP+       K     ++ +K+A   
Sbjct: 10689 TEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPE 10748

Query: 324   KK-QVFVPPKLPDVEKTELEQPLFSYEDIVE---SKKDENEIIQEKQTLEELPKEDVPEQ 379
             +K  V +P KL        E+P   +E+ +    +K+++ ++ +    +   PK  V E+
Sbjct: 10749 EKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEE 10808

Query: 380   YTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFY 412
                 PRK  A  +   V EV   K L P E+ +
Sbjct: 10809 KVPVPRKEVAPPVR--VPEV--PKELEPEEVAF 10837



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 4/58 (6%)

Query: 1138  RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN---SKCTAI-LTV 1191
             +W  DGSEI+   H  +  D     L I +C   D GEY   V N   SK  A+ LTV
Sbjct: 18470 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 12/136 (8%)

Query: 937  SYETEEGKTVILECQT--SHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXD 993
            S++  EG+T   + +        T W+H+ ++I +   H+ +I+E              D
Sbjct: 1465 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1524

Query: 994  VGVIKCIVKDQ----ETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINSE-T 1044
             G    + +++      S +L V+    +  P F+ KL++  +KE     ++V       
Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPN 1584

Query: 1045 ADVVWERDGEIIKPKK 1060
             D+VW ++ +II P K
Sbjct: 1585 PDIVWLKNSDIIVPHK 1600



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 19/81 (23%), Positives = 33/81 (40%)

Query: 174   PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPI 233
             P  + EE + EP   EE  +      E++   P ++     K   + PT   K+ +  P 
Sbjct: 11161 PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPA 11220

Query: 234   KIERKEMEVSTPQHAETVDGP 254
             K+ +K  E   P   +  + P
Sbjct: 11221 KVSKKIPEEKVPVPVQKKEAP 11241



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 8/107 (7%)

Query: 822   VEEPT--EENAEPPLFI---NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
             V EP   ++  EPP  I   N  +E  +K   T++L A +   P P +TW + +      
Sbjct: 18130 VPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK 18189

Query: 877   ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
               I     G  +E  I N   E D G Y     N AG  +   +V +
Sbjct: 18190 ARIDVTPVGSKLE--IRNAAHE-DGGIYSLTVENPAGSKTVSVKVLV 18233



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 4/83 (4%)

Query: 645   VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
             V  G+ +     +  +P P   W   G EI  DE+ +V  E+D   + SVL I N  +  
Sbjct: 18449 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV--ETD--NFSSVLTIKNCLRRD 18504

Query: 705   EGTYTVVAVNREGEASLPIVLKI 727
              G Y +   N  G  ++ + L +
Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTV 18527



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             G  ++ +    G P P +TW +    +K +        ++N + L I++   ED G +  
Sbjct: 23089 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLTIKDACREDVGHYVV 23147

Query: 584   VAKNAAGFASSTTELIV 600
                N+AG A  T  +IV
Sbjct: 23148 KLTNSAGEAIETLNVIV 23164



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 744   MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKV--KDE 800
             ++V  GE+ +L A + G P P + W K+ K ++    + +   T   T L  K     D 
Sbjct: 25644 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 25703

Query: 801   GVYTLKAENSEGIAETSAVITV 822
             G Y LK  N  G       + V
Sbjct: 25704 GQYILKLSNVGGTKSIPITVKV 25725



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 2/81 (2%)

Query: 524   GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
             GS +  +  V G P P+I W +    +   +   + Y     AT VI+     D+G +T 
Sbjct: 29989 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR-ATAVIKFCDRSDSGKYTL 30047

Query: 584   VAKNAAGF-ASSTTELIVEAP 603
               KNA+G  A S    ++++P
Sbjct: 30048 TVKNASGTKAVSVMVKVLDSP 30068


>UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whole
            genome shotgun sequence; n=4; Euteleostomi|Rep:
            Chromosome undetermined SCAF15134, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 7759

 Score =  287 bits (703), Expect = 3e-75
 Identities = 276/1136 (24%), Positives = 471/1136 (41%), Gaps = 54/1136 (4%)

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            V F K L+     EE  T  LEC+ S       W  + +EI      E++ +GR      
Sbjct: 10   VEFTKPLEDQ-TVEEEATATLECEVSRENADVLWLRDGQEIRKTKKYEMVIDGRKRALVI 68

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                  D     C  KD +TS  L V+    EF + L D EV+EK+ A  E E++ E   
Sbjct: 69   HDCTLDDSRTYTCGAKDFKTSCFLTVEPPHVEFTKPLHDVEVREKESARFECEVSRENIK 128

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
            V W +DG  I+ K  KY+   +G    L +  +   DE EY C  +    +  +TV+E  
Sbjct: 129  VRWFKDGSEIR-KGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDAKTSKSSGMLTVIEEE 187

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
                  L + +  + +      E++K DA V WFK   E+      +  +DGK++ L I 
Sbjct: 188  ARFTKNLSHVEAAERDSVKLICEVSKPDADVSWFKGDEELPEGGRYEHIVDGKRRILLIR 247

Query: 1167 DCDLDDAGEYSCEVGNS-KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
            D  + DAGEY+C +  + K +  L V E +  F +  P    V     A  T  +  ET 
Sbjct: 248  DLKMADAGEYNCRLSPAIKTSGSLKVNELAAEF-ISKPCSQEVVEGEKAVFTCIVSKETF 306

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
            +V W+K    +ED +K+ ++SD KKRTL+I+ C   D+  Y  ++   K++  LK  V+E
Sbjct: 307  EVKWFKGDKELEDGDKYQMVSDGKKRTLVIKNCELKDESGYVVIIGVTKASADLK--VLE 364

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSAS 1344
               KI+   ++     G +V L  +         +W+ N + + +  K      DS   S
Sbjct: 365  -KLKIITPLKDTEAIEGDEVVLNCEANT-DGAKAKWLQNGETLFESSKCVMVQRDS-VFS 421

Query: 1345 LTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDS-SSINICWD 1402
            L I+ V   D   + + L N  G  A    ++T+ ++      P + +ID+     + + 
Sbjct: 422  LRIRNVHKGDEANFSISLTNQRGEQATSSCSLTVKEESLRIIVP-LEDIDTQEKKTVSFS 480

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
               N  N+T + ++   +E+   + +  + ++ K   +I++        + A A      
Sbjct: 481  CKVNRPNAT-LKWLKSGEEVTFNKRLVYRVDVDKHILTIKDCTLADEGEYTAIA------ 533

Query: 1462 SDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
             D+  T E   +I E    +PT     LK+ T    ED E  C      +  V WY++G+
Sbjct: 534  GDSKSTAEL--IISE----APTDFSVHLKDQTITEFEDAEFICKL-TKEKADVKWYKNGR 586

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNED 1579
            +++        +                +C       +  +   + +++ PV I    +D
Sbjct: 587  EIREGPRYTFEKDGKMCILRIKECRPDDECEYACGVDDKRSRARLFVEEIPVEIIRPPQD 646

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            + +    G + L  A +      EV W +N   +    ++ + ++ K   +++ E++   
Sbjct: 647  VFE--PPGSDVLFEAELNK-DRVEVKWLRNNMPVVQGDKHQMMSEGKVHRLQVCEIRPRD 703

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
              +Y I A +    + +E+      K +  +    +R+    SV     P      L   
Sbjct: 704  QGEYRIIAKDKDARAKLELAAVPQIKTTDQKYVTDVRKPITMSVPYSAYPQAQADWL--- 760

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
             Y   +  P  N +      +     Y ++   ++ +  ++VI +N  G     E E  +
Sbjct: 761  -YD-NQSLPKENIYTSGEHTE-----YRLKDPQKSHQGHYKVIIKNTHG-----EGEAFI 808

Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXX 1818
                +DVP            D E V +TW   E +GGS +  Y +E +  + K W     
Sbjct: 809  SLDVIDVPGPVRNLQVVDTADGE-VSLTWEEPENDGGSKVTGYVLERRDVKRKTWTLVTD 867

Query: 1819 XXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                    +  L  +  Y FR+ ARN +G      +D  +        P  P N +V + 
Sbjct: 868  QAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNVETDKPVQAKNKFDVPDAPLNVIVGDV 927

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
            +    T+ W  PE +GGSPIT+YI+E +      W+ +           I ++ E  E I
Sbjct: 928  SKFGCTVSWERPEWDGGSPITSYIVELRDRTSVKWSSVHVTTADELSAIINDVIENKEYI 987

Query: 1938 FRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996
            FR+ AEN  GV  P+  SQ V++      PSPP   L  +    N V  +W TP  +GG+
Sbjct: 988  FRVRAENKAGVGKPSAASQPVKIMDPIEPPSPP-LNLAWQDQNKNSVQLTWETPLSNGGS 1046

Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             + GY +   +     W+         L + +  L     Y  R++A N  GLS+P
Sbjct: 1047 MITGYIVERCEDETDKWLRCNARLCPDLFYKVSGLKYGSKYNYRVFAENAAGLSKP 1102



 Score =  261 bits (639), Expect = 2e-67
 Identities = 191/683 (27%), Positives = 313/683 (45%), Gaps = 33/683 (4%)

Query: 1287 PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342
            PP+++      RE +   G+ +TL+   +  P P   W  N +++  +        DSK 
Sbjct: 4798 PPELILDAGMTREVKAMAGTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDSK- 4856

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L I+     D G Y L +EN  G       V +LDKP P     + ++ S S  + W 
Sbjct: 4857 --LEIRFCNREDCGDYTLTVENPAGSKTATCTVLVLDKPGPIQHLRVSDVRSDSAYLSWK 4914

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDI 1461
            +PE+ G + I  +VVE ++  +T+W+ V + +K ++  +++L   +SY FR  A N+   
Sbjct: 4915 DPEDNGGARITNFVVEKKDTASTQWVPVCSTSKKRSMMLKHLMEGTSYSFRVAAENQYGR 4974

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTW 1515
            S+  ET +  K +    +  P   K L +   +  E + L   +    GG  +    V +
Sbjct: 4975 SEYVETPKAIKAMNP--LFPPGPPKDLHHTDVDKTE-VWLAWNWPDRNGGSEITGFLVEF 5031

Query: 1516 YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSCVVGIQQKPVI 1573
              +G+K      T  +                ++  A N  G    +T+  +  Q+K V 
Sbjct: 5032 QEEGEKEWDEWKTV-SIPESHVTGLEEGKTYRFRVRAENAIGLSRPDTTLPILCQEKLVP 5090

Query: 1574 TISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             +   D+K       K G    + A++ GIP P   W   G ++ +     I T   ++V
Sbjct: 5091 PVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPTAKWSIEGEEITSQGNTKIDTDNFSTV 5150

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
            + I E  R+HS  Y +  SN AGT +V + + V D P+ P GPV + E++ +S+ IEW+P
Sbjct: 5151 LSINECTRNHSGTYLLTVSNPAGTKTVALNVTVLDVPAAPIGPVDILEVTPDSMKIEWRP 5210

Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
            P DDGG  +T Y +EK E +   W  V+       +  I +L +  EY+ R+ AQN +G 
Sbjct: 5211 PKDDGGSPITNYIVEKRESNKETWGGVSSSSL-ATSLNITRLQKGVEYVVRIRAQNKMGI 5269

Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809
               LES+P V + +  +P           +  ++V + W     +GGS I  Y +E + +
Sbjct: 5270 GAPLESKPTVAEHSF-MPPSPPGKPQPSDVSEDAVMLGWTMPLSDGGSQITGYLIERRHK 5328

Query: 1810 GKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
            G KW           R + L +     Y+FR++A N  G S P    D     + +T PS
Sbjct: 5329 GGKWIRVNRTPCKDMRYKVLGLFEGNDYEFRVFAENIAGYSGPSPISDPCKPCRPITVPS 5388

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
             P N  V + +  +V L WT+P  +GGSPI  Y +E K    + W K V +   + + C 
Sbjct: 5389 PPVNPKVKDYSKTTVDLVWTKPTKDGGSPILGYSVEMKKADTEEWKK-VNLDDFI-KQCA 5446

Query: 1928 ENIKEKDEII---FRISAENTVG 1947
              +K  +E +   FR+ A N VG
Sbjct: 5447 YRVKGLEEGVTYRFRVFATNMVG 5469



 Score =  228 bits (558), Expect = 1e-57
 Identities = 197/842 (23%), Positives = 355/842 (42%), Gaps = 49/842 (5%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F+K      V E      EC  V+     + W   G EI   +   +  +   H    VL
Sbjct: 101  FTKPLHDVEVREKESARFECE-VSRENIKVRWFKDGSEIRKGKKYEIIAQGRQH----VL 155

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             +       E  Y   A   +    L ++       +E  +  + L  +   + +SV L 
Sbjct: 156  IVHKSVFDDEAEYECDAKTSKSSGMLTVI-------EEEARFTKNLSHVEAAERDSVKLI 208

Query: 756  AQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             +V   P   ++W K ++  P              I +++  K+ D G Y  +   +   
Sbjct: 209  CEV-SKPDADVSWFKGDEELPEGGRYEHIVDGKRRILLIRDLKMADAGEYNCRLSPA--- 264

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
             +TS  + V E   E    P      QE+   EK     +  V++     + W++ ++ +
Sbjct: 265  IKTSGSLKVNELAAEFISKPCS----QEVVEGEKAVFTCI--VSKETF-EVKWFKGDKEL 317

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
               +      DG+   LVI N + + +SG    V      K+S   +V   +EK+  +  
Sbjct: 318  EDGDKYQMVSDGKKRTLVIKNCELKDESG---YVVIIGVTKASADLKV---LEKLKIITP 371

Query: 934  LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
            L K  E  EG  V+L C+ +      KW  N + +       ++Q               
Sbjct: 372  L-KDTEAIEGDEVVLNCEANTDGAKAKWLQNGETLFESSKCVMVQRDSVFSLRIRNVHKG 430

Query: 993  DVGVIKCIVKDQE-----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
            D       + +Q      +S  L VKE     I  L+D + +EK       ++N   A +
Sbjct: 431  DEANFSISLTNQRGEQATSSCSLTVKEESLRIIVPLEDIDTQEKKTVSFSCKVNRPNATL 490

Query: 1048 VWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
             W + GE +   K+  Y  +   HI  L I++ ++ DEGEY+ I  D   TAE+ + E P
Sbjct: 491  KWLKSGEEVTFNKRLVYRVDVDKHI--LTIKDCTLADEGEYTAIAGDSKSTAELIISEAP 548

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
             +    L++Q + +   A F  +LTK  A V+W+K+G EI+         DGK   L+I 
Sbjct: 549  TDFSVHLKDQTITEFEDAEFICKLTKEKADVKWYKNGREIREGPRYTFEKDGKMCILRIK 608

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
            +C  DD  EY+C V + +  A L VEE  +   +R P+ +  P  +D     E+  + ++
Sbjct: 609  ECRPDDECEYACGVDDKRSRARLFVEEIPVEI-IRPPQDVFEPPGSDVLFEAELNKDRVE 667

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            V W +    +   +K  ++S+ K   L + +    DQ EY  +  D  +  KL++  V  
Sbjct: 668  VKWLRNNMPVVQGDKHQMMSEGKVHRLQVCEIRPRDQGEYRIIAKDKDARAKLELAAV-- 725

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             P+I   +++Y       +T+ V Y A+PQ   +W+ +++ + K          +     
Sbjct: 726  -PQIKTTDQKYVTDVRKPITMSVPYSAYPQAQADWLYDNQSLPK---ENIYTSGEHTEYR 781

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            +K  + +  G YK+ ++N  G  +  +++ ++D P P     +++     +++ W+EPEN
Sbjct: 782  LKDPQKSHQGHYKVIIKNTHGEGEAFISLDVIDVPGPVRNLQVVDTADGEVSLTWEEPEN 841

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             G S +  YV+E +++    W  V +  ++ + ++  L+ +  Y FR  A N V      
Sbjct: 842  DGGSKVTGYVLERRDVKRKTWTLVTDQAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNV 901

Query: 1466 ET 1467
            ET
Sbjct: 902  ET 903



 Score =  224 bits (547), Expect = 2e-56
 Identities = 146/494 (29%), Positives = 228/494 (46%), Gaps = 34/494 (6%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G +  + A ++G P P V W K    L+ D   +I TK   S + I + KR  SS Y 
Sbjct: 1429 KAGSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYI 1488

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            IEA+N+ G ++  V + + DKP  P    I  EI+ +S  + W PP DDGG  +T Y +E
Sbjct: 1489 IEATNSCGRATATVDVNILDKPGPPAAFDIS-EITNDSCFLAWNPPRDDGGSRVTNYIVE 1547

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            +   D+  W +++   +   TY    L +  EY+FRV A+N  G     E   I+ +   
Sbjct: 1548 RRAADSEIWHRLSSTVKQT-TYRAAGLVKFKEYIFRVFAENQFGVGTPAEHPSIIARYPF 1606

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXX 1823
            D P           +  +SV ++W+  +++GGSPI  Y VE  + E  KW          
Sbjct: 1607 DTPGAPYNLQPSD-VAKDSVNLSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPIKD 1665

Query: 1824 A--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
               +++ L+    Y+FR+ A N  GT  P    D I +   + PP  P    V +    S
Sbjct: 1666 TNYKVKGLATRKKYKFRVLAENLAGTGKPSKETDLILVKDPIDPPWPPGKPTVKDVAKTS 1725

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
              L WT+PE +GG+ I +Y++E        W ++V    S+ E+ ++ + EK E  FR+ 
Sbjct: 1726 CFLMWTKPEHDGGAKIDSYVVEMLKSGTVDWIRVVD-NVSLLEYFLKGLMEKQEYSFRVR 1784

Query: 1942 AENTVGVSLPTESQ------------------SVRLEKHATV------PSPPTAP--LEI 1975
            A N  G S P+E                    + +  K A +        PP+AP  L++
Sbjct: 1785 AVNVAGESEPSEPSDPVLCKERLSTYLKCAHLNTQKPKEADITWLCVSSDPPSAPRWLDV 1844

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              +  +     W  PE DGG+P+  Y +  RDV +  W  V    V  L + +  L+E  
Sbjct: 1845 VNISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAV-DTTVKELIYTVTPLNEGS 1903

Query: 2036 TYMIRIYARNEIGL 2049
             Y+ R+ A N +G+
Sbjct: 1904 LYVFRVAAENAVGV 1917



 Score =  219 bits (536), Expect = 5e-55
 Identities = 205/883 (23%), Positives = 359/883 (40%), Gaps = 66/883 (7%)

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT-KLKVEVVEFP 1287
            + +K +    E+  L +      LI+      D+  YT  L  D KS + +++V V+  P
Sbjct: 1155 FGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLENDVKSVSGEIEVNVIAAP 1214

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
                D++     ++   ++          P   + V  + + +    K     +    T+
Sbjct: 1215 SAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVSRKTWVKVVTGIQDQEFTV 1274

Query: 1348 KKVENTDAGIYKLRLENNCG-----HADVEMNVTI-LDKPSPPGKPNILEIDSSSINICW 1401
              V      ++K+   N CG     + D  +N++     P PP      +  +SSI + W
Sbjct: 1275 TDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPDPPENLRWRDKSASSIFLTW 1334

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            + P+  G S I  Y ++  +  T +W    ++  +T+  +  L     Y +R  A+N + 
Sbjct: 1335 EPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKVTGLTEGQWYAYRVRALNRLG 1394

Query: 1461 ISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
             S   + T+  + +   +     ++ K L  +T +    IEL     G P+P+V W +  
Sbjct: 1395 ASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGKPEPRVKWTKAD 1454

Query: 1520 KKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---- 1571
              LK        T                   Y   A N  G    +  V I  KP    
Sbjct: 1455 LVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYIIEATNSCGRATATVDVNILDKPGPPA 1514

Query: 1572 ---VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
               +  I+N+            G   +   ++E       IW++  + ++       TT 
Sbjct: 1515 AFDISEITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQ------TTY 1568

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
                +++ KE      ++        A   S+ +    +D P  P   +   +++++SV 
Sbjct: 1569 RAAGLVKFKEYIFRVFAENQFGVGTPAEHPSI-IARYPFDTPGAPYN-LQPSDVAKDSVN 1626

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            + W  P +DGG  +T Y +E++EP++++WI+   +      Y ++ L    +Y FRV+A+
Sbjct: 1627 LSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPIKDTNYKVKGLATRKKYKFRVLAE 1686

Query: 1745 NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N  G  + + E++ I++K  +D P           +   S ++ W   E +GG+ I  Y 
Sbjct: 1687 NLAGTGKPSKETDLILVKDPID-PPWPPGKPTVKDVAKTSCFLMWTKPEHDGGAKIDSYV 1745

Query: 1804 VEIKQEGK-KW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            VE+ + G   W +           ++ L     Y FR+ A N  G S P    D +   +
Sbjct: 1746 VEMLKSGTVDWIRVVDNVSLLEYFLKGLMEKQEYSFRVRAVNVAGESEPSEPSDPVLCKE 1805

Query: 1862 TLT--------------------------PPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             L+                          PPS PR   V   +  S  LKWT PE +GGS
Sbjct: 1806 RLSTYLKCAHLNTQKPKEADITWLCVSSDPPSAPRWLDVVNISRSSANLKWTVPERDGGS 1865

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-S 1954
            PITNY++E + V+ K W  + T    +  + +  + E    +FR++AEN VGV    E +
Sbjct: 1866 PITNYVVEKRDVRRKGWQAVDTTVKEL-IYTVTPLNEGSLYVFRVAAENAVGVGPFCELT 1924

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
             SV  +   T P PP A L +  V    V   W  P+ DGG P+L Y+I  ++   T W+
Sbjct: 1925 DSVLAKDTFTTPGPPYA-LAVVAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWV 1983

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            + GK      K+ + D+ E      ++ A NE G+  P E  E
Sbjct: 1984 KCGKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTE 2026



 Score =  213 bits (519), Expect = 6e-53
 Identities = 191/717 (26%), Positives = 296/717 (41%), Gaps = 65/717 (9%)

Query: 1276 TTKLKVEVVEFPPKI-VDYERE--YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KK 1330
            T ++ VE ++ PP I +D   +    I+ G  + +    +  P P   W  + K    KK
Sbjct: 3372 TGEVLVEDIQLPPSISIDVTADDLLCIRAGDPIRIPATIKGRPAPKVTWDFDGKAKSHKK 3431

Query: 1331 CK-HTKPSIDSK-----SASLTIKKVE-NTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
             K HT P +DS+     + S+ I  V   T +G Y +  +N  G   V + V +LD P P
Sbjct: 3432 NKLHTLP-VDSEVESTDTTSVVIVPVSLRTHSGRYTITAKNKSGQKHVNVRVIVLDVPGP 3490

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QN 1442
            P    + +I  S++ + W  PE+ G   I  Y +E + I    W  V     +Q  +   
Sbjct: 3491 PKDLKVTDITRSTVRLIWKLPESDGGERIKSYFIEKKCITDKAWTKVNAACASQAYVVPG 3550

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIEL 1501
            L     Y FR  A N +     + TTE         I  P     LK N+ T+    +  
Sbjct: 3551 LLEGQDYLFRVRAENRLGFGPFTTTTE--PAHARDPIYPPDPPTKLKVNLVTKNTVTLSW 3608

Query: 1502 TCIF--GGVPQP-----KVTWYRDGKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCI 1551
             C    GG P       +++W   GK+ +T K   +                    ++  
Sbjct: 3609 ECPKNNGGSPVTHYIIERLSWDTSGKEKETWKQCNKRDVEELSFVVEDLQEGGEYEFRIK 3668

Query: 1552 AFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            A N  G    S   G   I+ +    I       + + G +  + A + G P P + W K
Sbjct: 3669 AVNAAGPSRPSTTAGPLVIKDQTFAPIIELRESMEGEEGCDVSMVAKVSGCPFPTLTWQK 3728

Query: 1609 NGN-KLEN------DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
                K E       D+  N    +    + I++  RS S+ Y++ ASN+ G+ + ++ L 
Sbjct: 3729 ASTAKPEEKVAILYDQHINKLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSVTKDIKLS 3788

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            V+  P  P GPV   E+  E + + W PP DDGG ++T Y +EK E +   W+ V+D  +
Sbjct: 3789 VFGPPGPPVGPVKFTEVFAERIGLAWNPPTDDGGSKITSYVVEKREDNRKSWVHVSDDPK 3848

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            +   + + +L EN EY FR++AQN  G    L S+P   +    VP           +  
Sbjct: 3849 EC-AFVVTRLTENHEYEFRIMAQNKFGVGPPLLSDPEKARNLFTVPG-QCEKPTVTEVCL 3906

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA------RIQKLSINTT 1834
            ES+ + W   + +GGSP+  Y +E K+   K+W                  +  L     
Sbjct: 3907 ESMTVNWEEPKYDGGSPVTGYFIEKKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAM 3966

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            YQFR+ A N  G  LP    D I     + PP  P   V+ + T  SV L+W  P  +GG
Sbjct: 3967 YQFRVIAANAAGCGLPSMPSDPILCRDPIKPPGPPTPKVI-DWTRSSVELEWIPPLLDGG 4025

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            S + +       ++G   TK V  G          +KE     FR+ A N  GV  P
Sbjct: 4026 SKVKD-----TEIRG---TKFVVAG----------LKEGGLYRFRVRAVNAAGVGEP 4064



 Score =  209 bits (510), Expect = 7e-52
 Identities = 181/698 (25%), Positives = 304/698 (43%), Gaps = 40/698 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNI-TKTQ 1437
            P  P +P +LE+   S  I W+ P + G   I  Y++E +E     W+  + + I  K +
Sbjct: 4595 PDAPKQPTVLEVYHDSALISWEPPAD-GGKPITGYIIERKETMANRWVRCNTERIHPKVE 4653

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE--YYK--VIKE---TKIQSPTVEKPLKN 1490
              + +L     Y FR  A NEV + D S  ++  + K  ++K      ++     K    
Sbjct: 4654 YWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPIFAKDPIVKPGPPVNLKVIDFSKESVT 4713

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYK 1549
            ++ +P  D     IFG + + +     +  K+  T  +  E +               ++
Sbjct: 4714 LSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVNHTPDSCQETKFKVINLEEGALCN--FR 4771

Query: 1550 CIAFNDHGEVETSCV---VGIQQK---PVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPP 1602
             +A N  GE E + +   V +Q +   P + +     ++ K   G    + A I+G+P P
Sbjct: 4772 VMAVNAAGESEPAYLREAVRVQDRLEPPELILDAGMTREVKAMAGTHITLMATIKGVPFP 4831

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             V W KN  + E     +I T +  S + I+   R     YT+   N AG+ +   T+ V
Sbjct: 4832 TVTWKKN--EAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVENPAGSKTATCTVLV 4889

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             DKP  P   + + ++  +S  + WK P D+GG  +T + +EK +  + +W+ V    + 
Sbjct: 4890 LDKPG-PIQHLRVSDVRSDSAYLSWKDPEDNGGARITNFVVEKKDTASTQWVPVCSTSKK 4948

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDN 1781
              +  ++ L E   Y FRV A+N  G SE +E+ P  IK    + P           +D 
Sbjct: 4949 -RSMMLKHLMEGTSYSFRVAAENQYGRSEYVET-PKAIKAMNPLFPPGPPKDLHHTDVDK 5006

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIY 1840
              V++ W   ++NGGS I  + VE ++EG+K W          + +  L    TY+FR+ 
Sbjct: 5007 TEVWLAWNWPDRNGGSEITGFLVEFQEEGEKEWDEWKTVSIPESHVTGLEEGKTYRFRVR 5066

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--T 1898
            A N IG S P T+   I   + L PP    +  + E            P    G P+   
Sbjct: 5067 AENAIGLSRPDTTLP-ILCQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPTA 5125

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             + IE + +  +  TKI T   S        +   +E     S    + VS P  +++V 
Sbjct: 5126 KWSIEGEEITSQGNTKIDTDNFST-------VLSINECTRNHSGTYLLTVSNPAGTKTVA 5178

Query: 1959 LEKHAT-VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
            L      VP+ P  P++I  V  + +   W  P+ DGG+P+  Y +  R+  K  W  V 
Sbjct: 5179 LNVTVLDVPAAPIGPVDILEVTPDSMKIEWRPPKDDGGSPITNYIVEKRESNKETWGGVS 5238

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
               + T   NI  L +   Y++RI A+N++G+  PLES
Sbjct: 5239 SSSLAT-SLNITRLQKGVEYVVRIRAQNKMGIGAPLES 5275



 Score =  200 bits (487), Expect = 4e-49
 Identities = 123/406 (30%), Positives = 186/406 (45%), Gaps = 13/406 (3%)

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
            + P + +   D K   KVGD   ++    G P P + W KN  +L+ D++ N+ +     
Sbjct: 4399 EPPTLELDIRD-KMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHL 4457

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             + I + +R HS  Y +   NTAG+ S   T+ V D+P  PEGPV+  E+ R  + I W 
Sbjct: 4458 SLTIAKARRDHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVFNEVYRNYMVISWN 4517

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPV 1747
            PPLDDGG  ++ Y IEK + + + W+ V        T C + KL E  EY+ R++AQN  
Sbjct: 4518 PPLDDGGCAISNYIIEKRDTNRDLWMPV--TSSCTRTTCKVPKLIEGREYIIRIMAQNIY 4575

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G S+ LES     +    VP           + ++S  I+W P   +GG PI  Y +E K
Sbjct: 4576 GISDPLESAETKARDIYKVPD-APKQPTVLEVYHDSALISWEP-PADGGKPITGYIIERK 4633

Query: 1808 QE-GKKW---KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
            +    +W               +  L     Y+FR+ A NE+G   P      I     +
Sbjct: 4634 ETMANRWVRCNTERIHPKVEYWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPIFAKDPI 4693

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
              P  P N  V + +  SVTL W  P   G   I  Y++EF+    + W+K+     S  
Sbjct: 4694 VKPGPPVNLKVIDFSKESVTLSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVNHTPDSCQ 4753

Query: 1924 E--HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
            E    + N++E     FR+ A N  G S P    ++VR++     P
Sbjct: 4754 ETKFKVINLEEGALCNFRVMAVNAAGESEPAYLREAVRVQDRLEPP 4799



 Score =  190 bits (464), Expect = 3e-46
 Identities = 139/521 (26%), Positives = 220/521 (42%), Gaps = 24/521 (4%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            D  +   ++ G  + L V  +  P P   W   +  +K+ +    +       L ++ + 
Sbjct: 7233 DLRKALVLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDTLLMVEDIN 7292

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              DAG Y L LEN+ G     + V +LD P PP    + E   +   I WD P   G S 
Sbjct: 7293 RYDAGKYVLMLENSSGSKSYTIVVKVLDSPGPPVNLTVKETTRNQAWITWDAPLIDGGSP 7352

Query: 1412 IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            +  YVVE +  +   W  V     KT   I NL+   +Y FR  A N   I +  ET   
Sbjct: 7353 VKSYVVEKRLAERKAWTCVSAECPKTSFRILNLEAGQAYCFRVLAENNYGIGEGCETPGS 7412

Query: 1471 YKVIKET-KIQSPTVEKPLKNITT----EPNED--IELTCIFGGVPQPKVTWYRDGKKLK 1523
             +  ++   +     +K  KN  T    +P  D    +T     + + +  W    K++K
Sbjct: 7413 VRASEQPGPVTDFKAQKTTKNSVTLAWKKPISDGGSYITAYVLELSEGEDKW----KQIK 7468

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISN----E 1578
              K                     ++  A N+ GE   T   V  + + V+   N     
Sbjct: 7469 KGK-----EASHTMSELTEGKEYTFRVRALNESGEGPPTELTVMAKDQFVLPDCNLSGLH 7523

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            D     K G    +   + G+P P  +W K    L +     +   +  + + I++ +R 
Sbjct: 7524 DNCYIVKEGSTTRINIPVIGVPYPTALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRG 7583

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
             +  YTI   N+AG+   + +LKV  +P    GP+   EI+ + +T+EW PP DDGG E+
Sbjct: 7584 DADTYTINVRNSAGSKDCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAEV 7643

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            + Y +EK    +N+W  VA   +      I +L E  EY+FRV A+N  G  E L SEP+
Sbjct: 7644 SNYIVEKRRTTDNKWATVASAIQKTSMRVI-RLQEGKEYIFRVFAENKYGVGEYLRSEPV 7702

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            + +   +VP           I +ES  +TW   +  GGSPI
Sbjct: 7703 IAQHPFNVPG-APAPPEIVSIRHESAILTWADPKDTGGSPI 7742



 Score =  188 bits (458), Expect = 1e-45
 Identities = 182/732 (24%), Positives = 281/732 (38%), Gaps = 38/732 (5%)

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTS-- 1439
            PPGKP  +++  SS+++ W  P++ G S +I Y +EY ++   +W     N    QT   
Sbjct: 6725 PPGKPEPMDVTKSSVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESY 6784

Query: 1440 -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497
             +  L+    Y+FR  A   +++S ASE ++   VI E       +   +KN I  +  E
Sbjct: 6785 VVTGLEEGQQYQFRVIAKTAINVSMASELSDPIPVIAENVPPRVDLGINMKNLIVVKAGE 6844

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            ++ L     G P PKVTW RDG  L  A+       ++                Y  +A 
Sbjct: 6845 NVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVHLLELYSVTRKETGDYTILAE 6904

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            N +G    +  V +  KP    S +  K    +V   W       G      I  K    
Sbjct: 6905 NINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEPPLADGGSEITNYIIEKRETS 6964

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPS 1667
              N            +   +++L   H  ++ + A N  G     +T  V     YD P 
Sbjct: 6965 RANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYGVGDPAMTDPVTVKNPYDVPG 7024

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
              E PVI   I+++S+T+ WK P +DG   +  Y +EK E     W KV        T  
Sbjct: 7025 PCEPPVI-TNITKDSMTVSWKAPANDGRAPILGYMVEKREATELTWAKVNRRPVIDRTIK 7083

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
              +L E  EY FRVIA N  G  +  ++    +      P               S+ ++
Sbjct: 7084 ASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPVYPPGPPAFPKVVDSTRSSISLS 7143

Query: 1788 WFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARN 1843
            W     +GG  II Y VE K+ E + W          A    +  L  NT YQFR+ A N
Sbjct: 7144 WTKPAYDGGCEIIGYLVECKRAEAEDWTKCNVPKKLQATKFLVTSLMDNTEYQFRVSALN 7203

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSPITNYI 1901
            +IG S P            L PP    +  + ++      VT++   P     +P   + 
Sbjct: 7204 KIGFSEPSDVPGNHMPKDILLPPEAELDADLRKALVLRAGVTMRLYVPVRGRPAPKVTWT 7263

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
                 +K +    I T         +E+I   D   + +  EN+ G    ++S ++ + K
Sbjct: 7264 KVNYNLKERQGLLINTSEWDT-LLMVEDINRYDAGKYVLMLENSSG----SKSYTI-VVK 7317

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                P PP   L ++    N    +W  P  DGG+P+  Y +  R   +  W  V   + 
Sbjct: 7318 VLDSPGPP-VNLTVKETTRNQAWITWDAPLIDGGSPVKSYVVEKRLAERKAWTCV-SAEC 7375

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXX 2081
                F I +L     Y  R+ A N  G+ E  E+       PG    A E+PG  T+   
Sbjct: 7376 PKTSFRILNLEAGQAYCFRVLAENNYGIGEGCET-------PG-SVRASEQPGPVTDFKA 7427

Query: 2082 XXXXXXXXXXXW 2093
                       W
Sbjct: 7428 QKTTKNSVTLAW 7439



 Score =  184 bits (449), Expect = 2e-44
 Identities = 217/924 (23%), Positives = 371/924 (40%), Gaps = 65/924 (7%)

Query: 1194 PSINFTLRLPEFILVPANTDAYLTV---EIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            P +   ++L E I+V A T   L      IP  T    W  +   I       + +D   
Sbjct: 5091 PVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPT--AKWSIEGEEITSQGNTKIDTDNFS 5148

Query: 1251 RTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
              L I +CT +    Y   + +     T  L V V++ P   +       I   +  ++ 
Sbjct: 5149 TVLSINECTRNHSGTYLLTVSNPAGTKTVALNVTVLDVPAAPIG---PVDILEVTPDSMK 5205

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKP-----SIDSKSASLTIKKVENTDAGIYKLRLE 1363
            ++++  P+ +    + + I++K +  K      S  S + SL I +++     + ++R +
Sbjct: 5206 IEWRP-PKDDGGSPITNYIVEKRESNKETWGGVSSSSLATSLNITRLQKGVEYVVRIRAQ 5264

Query: 1364 NNCG-HADVEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
            N  G  A +E   T+ +     PSPPGKP   ++   ++ + W  P + G S I  Y++E
Sbjct: 5265 NKMGIGAPLESKPTVAEHSFMPPSPPGKPQPSDVSEDAVMLGWTMPLSDGGSQITGYLIE 5324

Query: 1419 YQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             +     +WI V        +  +  L   + Y FR +A N    S  S  ++  K  + 
Sbjct: 5325 RRH-KGGKWIRVNRTPCKDMRYKVLGLFEGNDYEFRVFAENIAGYSGPSPISDPCKPCRP 5383

Query: 1477 TKIQSPTVEKPLKN--------ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
              + SP V   +K+        + T+P +D   + I G   + K     + KK+      
Sbjct: 5384 ITVPSPPVNPKVKDYSKTTVDLVWTKPTKDGG-SPILGYSVEMKKADTEEWKKVNLDD-- 5440

Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE---DIKQKHK 1585
            +  +               ++  A N  G+ E+  V        I I  E   D   + +
Sbjct: 5441 FIKQCAYRVKGLEEGVTYRFRVFATNMVGDGESREVPESVVAQDILIPPEIEMDATCRER 5500

Query: 1586 V----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
            V    G    +   I+  P PEVIW K    LEN K   I        +RIKE  R+   
Sbjct: 5501 VTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEATRADHG 5560

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
            KY ++ASN  G +S  +T+ V D+PS  +  +     +++S  I W+ P D+GG E+T Y
Sbjct: 5561 KYILKASNEGGEASCTITVNVLDRPSHCQN-LHTTYATKDSCMINWEAPKDNGGSEITNY 5619

Query: 1702 AIEKHEPDNNRWIKVAD--VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PI 1758
             +E  EP    W  ++    +R ++     KL E  EY+FRV A+N +G    +E++ P+
Sbjct: 5620 IVECREPSVRMWSMISSNCTNRKIKA----KLMEGHEYLFRVCAENKMGPGPCVETKTPL 5675

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXX 1817
            +    L+ P           I    VY+ W   + +GGSP + Y +E K ++ ++W+   
Sbjct: 5676 LAIDPLEKPG-EPENFRVTDIGKNHVYLRWRKPDYDGGSPNLSYNLECKAKDAEEWEKLN 5734

Query: 1818 XXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                        K   N TY FR+   NE G S      D I + + +  P        +
Sbjct: 5735 TGVLTDTFFLADKCIENQTYTFRVQTVNEGGESTWVKLSD-ILVKEEIQKPVIDLKLAGT 5793

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
             +     +++          P   +I + K V G +       G    +  +   +  D 
Sbjct: 5794 LTVKVGESVRMEAALRGKPQPEVKWIKD-KAV-GDNPRISYETGPDYSKFLLTKSRRTDT 5851

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              + I+A N  G      + SV       VP  P   L +  +G++     W  PE DGG
Sbjct: 5852 GKYIITATNLAGTFTAYANVSV-----LDVPG-PVRNLRLTGIGADKCRVVWDAPEDDGG 5905

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              +  Y +   +  + +W       V T   N+  L E + Y+ R+ A N++G + P   
Sbjct: 5906 CEVDSYILEKCETRRMVW-STYSASVVTPYCNVIRLVEGNEYIFRVRAENKMG-TGPATE 5963

Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079
             +P  V          +P E T+V
Sbjct: 5964 TKPVTVKTQFNKPGPPDPPEVTKV 5987



 Score =  180 bits (438), Expect = 4e-43
 Identities = 204/912 (22%), Positives = 352/912 (38%), Gaps = 66/912 (7%)

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252
            P ++  + +   I+V A  + +L  E+  + L  VTW +    +   E   ++       
Sbjct: 6826 PRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVHL 6885

Query: 1253 LIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP--PKIVDYEREY--RIKRGSDVT 1306
            L +   T  +  +YT +   ++      +KV+V++ P  P  V   + +  R+K   +  
Sbjct: 6886 LELYSVTRKETGDYTILAENINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEPP 6945

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
            L             +I+  +   +        +I       +++K+       +++  EN
Sbjct: 6946 LADGGSEITN----YIIEKRETSRANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAEN 7001

Query: 1365 NCGHADVEMN--VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
              G  D  M   VT+    D P P   P I  I   S+ + W  P N G + I+ Y+VE 
Sbjct: 7002 QYGVGDPAMTDPVTVKNPYDVPGPCEPPVITNITKDSMTVSWKAPANDGRAPILGYMVEK 7061

Query: 1420 QEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            +E     W  V        +I+   L   + Y FR  A+N+  +   S+ +     +   
Sbjct: 7062 REATELTWAKVNRRPVIDRTIKASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPV 7121

Query: 1478 KIQSP-----TVEKPLKNIT---TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
                P      V+    +I+   T+P  D     I G + + K     D  K    K   
Sbjct: 7122 YPPGPPAFPKVVDSTRSSISLSWTKPAYDGGCE-IIGYLVECKRAEAEDWTKCNVPKKLQ 7180

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE-----DIKQKH 1584
              +               ++  A N  G  E S V G      I +  E     D+++  
Sbjct: 7181 ATKFLVTSLMDNTEYQ--FRVSALNKIGFSEPSDVPGNHMPKDILLPPEAELDADLRKAL 7238

Query: 1585 --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
              + G    +   + G P P+V W K    L+  +   I T E  +++ ++++ R  + K
Sbjct: 7239 VLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDTLLMVEDINRYDAGK 7298

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y +   N++G+ S  + +KV D P  P   + ++E +R    I W  PL DGG  +  Y 
Sbjct: 7299 YVLMLENSSGSKSYTIVVKVLDSPGPPVN-LTVKETTRNQAWITWDAPLIDGGSPVKSYV 7357

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            +EK   +   W  V+  +    ++ I  L     Y FRV+A+N  G  E  E+   V   
Sbjct: 7358 VEKRLAERKAWTCVS-AECPKTSFRILNLEAGQAYCFRVLAENNYGIGEGCETPGSV--R 7414

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822
            A + P             N SV + W     +GGS I  Y +E+ +   KWK        
Sbjct: 7415 ASEQPGPVTDFKAQKTTKN-SVTLAWKKPISDGGSYITAYVLELSEGEDKWKQIKKGKEA 7473

Query: 1823 XARIQKLSINTTYQFRIYARNEIG----TSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
               + +L+    Y FR+ A NE G    T L   + D+  +            ++V E +
Sbjct: 7474 SHTMSELTEGKEYTFRVRALNESGEGPPTELTVMAKDQFVLPDCNLSGLHDNCYIVKEGS 7533

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
            +  + +    P      P T    +  T+ G +    V     +    I + +  D   +
Sbjct: 7534 TTRINI----PVIGVPYP-TALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTY 7588

Query: 1939 RISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
             I+  N+ G      S+  +   K    P   T P++   + ++ +   WG P+ DGGA 
Sbjct: 7589 TINVRNSAG------SKDCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAE 7642

Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-----SEP 2052
            +  Y +  R  T   W  V      T    IR L E   Y+ R++A N+ G+     SEP
Sbjct: 7643 VSNYIVEKRRTTDNKWATVASAIQKTSMRVIR-LQEGKEYIFRVFAENKYGVGEYLRSEP 7701

Query: 2053 LESDEPFKVIPG 2064
            + +  PF V PG
Sbjct: 7702 VIAQHPFNV-PG 7712



 Score =  178 bits (434), Expect = 1e-42
 Identities = 158/700 (22%), Positives = 287/700 (41%), Gaps = 41/700 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            PSPP  P + +   +++++ W +P   G S I+ Y VE ++ DT EW  V     I +  
Sbjct: 5387 PSPPVNPKVKDYSKTTVDLVWTKPTKDGGSPILGYSVEMKKADTEEWKKVNLDDFIKQCA 5446

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
              ++ L+   +YRFR +A N V   ++ E  E   V+ +  +  P +E      + +T  
Sbjct: 5447 YRVKGLEEGVTYRFRVFATNMVGDGESREVPE--SVVAQDILIPPEIEMDATCRERVTVR 5504

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCI- 1551
               ++ +       P+P+V W ++   L+ +K     +N                 K I 
Sbjct: 5505 VGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEATRADHGKYIL 5564

Query: 1552 -AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKN 1609
             A N+ GE   +  V +  +P      +++   +   D  ++     +     E+  Y  
Sbjct: 5565 KASNEGGEASCTITVNVLDRPSHC---QNLHTTYATKDSCMINWEAPKDNGGSEITNYIV 5621

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663
              +  + + +++ +   T+     +L   H   + + A N  G      T +  + +   
Sbjct: 5622 ECREPSVRMWSMISSNCTNRKIKAKLMEGHEYLFRVCAENKMGPGPCVETKTPLLAIDPL 5681

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
            +KP +PE    + +I +  V + W+ P  DGG     Y +E    D   W K+       
Sbjct: 5682 EKPGEPEN-FRVTDIGKNHVYLRWRKPDYDGGSPNLSYNLECKAKDAEEWEKLNTGVLTD 5740

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NE 1782
              +   K  EN  Y FRV   N  G S  ++   I++K  +  P           +   E
Sbjct: 5741 TFFLADKCIENQTYTFRVQTVNEGGESTWVKLSDILVKEEIQKPVIDLKLAGTLTVKVGE 5800

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
            SV +    + +    P + + ++ K  G   +         ++  + K     T ++ I 
Sbjct: 5801 SVRME--AALRGKPQPEVKW-IKDKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIIT 5857

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N  GT   Y +   + +      P   RN  ++   +    + W  PE +GG  + +Y
Sbjct: 5858 ATNLAGTFTAYANVSVLDV------PGPVRNLRLTGIGADKCRVVWDAPEDDGGCEVDSY 5911

Query: 1901 IIEFKTVKGKSWTKIVTVGGSV-HEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
            I+E    +   W+   T   SV   +C +  + E +E IFR+ AEN +G    TE++ V 
Sbjct: 5912 ILEKCETRRMVWS---TYSASVVTPYCNVIRLVEGNEYIFRVRAENKMGTGPATETKPVT 5968

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
            ++     P PP  P E+  V  + +   W  PE DGG  + GY +  ++     W+   K
Sbjct: 5969 VKTQFNKPGPPDPP-EVTKVSKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNK 6027

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              ++  +  + +L  NH Y  R+ A NE+GL EP +   P
Sbjct: 6028 SPISERRMKVSNLIPNHEYQFRVKAENEVGLGEPSKPSRP 6067



 Score =  175 bits (426), Expect = 1e-41
 Identities = 202/870 (23%), Positives = 343/870 (39%), Gaps = 58/870 (6%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            VTW  KK+  E   +  + +      L IR C  +D  +YT  + +   +      V+  
Sbjct: 4833 VTW--KKNEAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVENPAGSKTATCTVL-- 4888

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSID 1339
               ++D     +  R SDV     Y ++  P D        ++V  K     +       
Sbjct: 4889 ---VLDKPGPIQHLRVSDVRSDSAYLSWKDPEDNGGARITNFVVEKKDTASTQWVPVCST 4945

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI--LDKPSPPGKPNIL---EID 1393
            SK  S+ +K +    +  +++  EN  G ++ VE    I  ++   PPG P  L   ++D
Sbjct: 4946 SKKRSMMLKHLMEGTSYSFRVAAENQYGRSEYVETPKAIKAMNPLFPPGPPKDLHHTDVD 5005

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
             + + + W+ P+  G S I  ++VE+QE    EW   K ++  ++ +  L+   +YRFR 
Sbjct: 5006 KTEVWLAWNWPDRNGGSEITGFLVEFQEEGEKEWDEWKTVSIPESHVTGLEEGKTYRFRV 5065

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQ 1510
             A N + +S    T     ++ + K+  P VE   K ++ I  +    I L  I  G+P 
Sbjct: 5066 RAENAIGLSRPDTT---LPILCQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPV 5122

Query: 1511 PKVTWYRDGKKLKT---AKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            P   W  +G+++ +    K   +N                 Y     N  G    +  V 
Sbjct: 5123 PTAKWSIEGEEITSQGNTKIDTDNFSTVLSINECTRNHSGTYLLTVSNPAGTKTVALNVT 5182

Query: 1567 IQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NIT 1622
            +   P   I   DI +     +  EW       G P    I      K E++KE    ++
Sbjct: 5183 VLDVPAAPIGPVDILEVTPDSMKIEWRPPKDDGGSPITNYI----VEKRESNKETWGGVS 5238

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYD---KPSKPEGPVIMREI 1678
            +    + + I  L++       I A N  G  + +E    V +    P  P G     ++
Sbjct: 5239 SSSLATSLNITRLQKGVEYVVRIRAQNKMGIGAPLESKPTVAEHSFMPPSPPGKPQPSDV 5298

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            S ++V + W  PL DGG ++T Y IE+      +WI+V         Y +  L E  +Y 
Sbjct: 5299 SEDAVMLGWTMPLSDGGSQITGYLIERRH-KGGKWIRVNRTPCKDMRYKVLGLFEGNDYE 5357

Query: 1739 FRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
            FRV A+N  G+S  +  S+P      + VPS              +V + W    K+GGS
Sbjct: 5358 FRVFAENIAGYSGPSPISDPCKPCRPITVPS-PPVNPKVKDYSKTTVDLVWTKPTKDGGS 5416

Query: 1798 PIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
            PI+ Y VE+K    +E KK            R++ L    TY+FR++A N +G       
Sbjct: 5417 PILGYSVEMKKADTEEWKKVNLDDFIKQCAYRVKGLEEGVTYRFRVFATNMVGDGESREV 5476

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
             + +     L PP    +    E  +  V             P    I   +    ++  
Sbjct: 5477 PESVVAQDILIPPEIEMDATCRERVTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSK 5536

Query: 1914 KIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
            +I  +      H  I+     D   + + A N  G +  T + +V L++    PS     
Sbjct: 5537 RITIIQNLPVVHLRIKEATRADHGKYILKASNEGGEASCTITVNV-LDR----PS-HCQN 5590

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            L       +  M +W  P+ +GG+ +  Y +  R+ +  MW  +     N  K   + L 
Sbjct: 5591 LHTTYATKDSCMINWEAPKDNGGSEITNYIVECREPSVRMWSMISSNCTNR-KIKAK-LM 5648

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
            E H Y+ R+ A N++G    +E+  P   I
Sbjct: 5649 EGHEYLFRVCAENKMGPGPCVETKTPLLAI 5678



 Score =  161 bits (392), Expect = 1e-37
 Identities = 118/391 (30%), Positives = 178/391 (45%), Gaps = 25/391 (6%)

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
            QKPVI +         KVG+   + A + G P PEV W K+    +N +  +  T    S
Sbjct: 5782 QKPVIDLKLAGTLTV-KVGESVRMEAALRGKPQPEVKWIKDKAVGDNPR-ISYETGPDYS 5839

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
               + + +R+ + KY I A+N AGT +    + V D P  P   + +  I  +   + W 
Sbjct: 5840 KFLLTKSRRTDTGKYIITATNLAGTFTAYANVSVLDVPG-PVRNLRLTGIGADKCRVVWD 5898

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPV 1747
             P DDGG E+  Y +EK E     W   +     V  YC + +L E  EY+FRV A+N +
Sbjct: 5899 APEDDGGCEVDSYILEKCETRRMVWSTYSA--SVVTPYCNVIRLVEGNEYIFRVRAENKM 5956

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G   A E++P+ +KT  + P           +  + + + W P E +GG  I  Y +E K
Sbjct: 5957 GTGPATETKPVTVKTQFNKPGPPDPPEVTK-VSKDEMTVVWAPPENDGGKSITGYILERK 6015

Query: 1808 QE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
            ++   +W           R  +  L  N  YQFR+ A NE+G   P      I       
Sbjct: 6016 EKRAVRWVPCNKSPISERRMKVSNLIPNHEYQFRVKAENEVGLGEPSKPSRPIAA----- 6070

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-------GKSWTKIVT 1917
                P    VS+ST  S+TL W++P  +GG+PI  Y ++ +           + W +I T
Sbjct: 6071 --KDPIGLKVSDSTKTSITLSWSKPVYDGGAPIIGYSLDLRLKSEADPEKPSEGWKRIDT 6128

Query: 1918 VGGSV-HEHCIENIKEKDEIIFRISAENTVG 1947
             G  V  E  I  + EK E  F++SA+N VG
Sbjct: 6129 HGPLVLTEFTINQLDEKKEYEFKVSAQNQVG 6159



 Score =  159 bits (387), Expect = 6e-37
 Identities = 120/474 (25%), Positives = 204/474 (43%), Gaps = 22/474 (4%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            + A + G P P++ W ++  ++   KE  + T   ++ + IK  KR H   YT+ A N  
Sbjct: 4126 IIAYVSGKPAPQISWCRDDGEVP--KEAKVETTGISNSLVIKNCKRQHQGIYTLSAKNEG 4183

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G     V ++V D P     P     ++ +S  + W  P D+GG  +T Y IEK E D  
Sbjct: 4184 GERRKAVIVEVLDVPGPVGLPFAGENLTNDSCKLTWYSPEDNGGSAITNYIIEKRESDRM 4243

Query: 1712 RWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSX 1769
             W  V+  V R+     +Q L +   Y FR+ A+N +G    +E++ +V IK  + VP  
Sbjct: 4244 GWTSVSYTVTRN--NAVVQGLLDGKGYFFRIAAENIIGMGPFIETDKMVLIKDPISVPE- 4300

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK----KWKXXXXXXXXXAR 1825
                     +   S+ + W P + +GG+ + +Y +E +  G+    +             
Sbjct: 4301 RPEDLIISAVTKTSISVAWMPPKYDGGAEVTEYVLESRTIGRDNFVRVGGDTKLMDRKFT 4360

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            +  L   ++++FR+ A N++G   P  +   +     L PP+   +  + +     V   
Sbjct: 4361 LSGLKEGSSHEFRVSAVNQVGQGKPSFATKPVQCKDELEPPTLELD--IRDKMMVKVGDS 4418

Query: 1886 WTEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
             T     GG  +P  ++    + +KG     + +    +    I   +      + ++ E
Sbjct: 4419 CTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHL-SLTIAKARRDHSGCYCVNVE 4477

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            NT G      + +V        P PP  P+    V  N ++ SW  P  DGG  +  Y I
Sbjct: 4478 NTAGSRSGACTITV-----VDRPQPPEGPVVFNEVYRNYMVISWNPPLDDGGCAISNYII 4532

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              RD  + +WM V      T    +  L E   Y+IRI A+N  G+S+PLES E
Sbjct: 4533 EKRDTNRDLWMPVTSSCTRT-TCKVPKLIEGREYIIRIMAQNIYGISDPLESAE 4585



 Score =  158 bits (384), Expect = 1e-36
 Identities = 121/458 (26%), Positives = 208/458 (45%), Gaps = 30/458 (6%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIM- 1675
            ++TT ++ S I I ++  +    + + A N AG    S+    +K+ D    P  P+ + 
Sbjct: 966  HVTTADELSAI-INDVIENKEYIFRVRAENKAGVGKPSAASQPVKIMDPIEPPSPPLNLA 1024

Query: 1676 -REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNE 1733
             ++ ++ SV + W+ PL +GG  +T Y +E+ E + ++W++  A +  D+  Y +  L  
Sbjct: 1025 WQDQNKNSVQLTWETPLSNGGSMITGYIVERCEDETDKWLRCNARLCPDL-FYKVSGLKY 1083

Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
              +Y +RV A+N  G S+      ++     D P            D   V +   P   
Sbjct: 1084 GSKYNYRVFAENAAGLSKPTN---VIGPLLADDPHVGPTFDLSAFKDGLEVIV---PHPL 1137

Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA---RNEIGT-SL 1849
                PI  Y   +     KW              +L+  +T+   I     R + GT +L
Sbjct: 1138 VIRVPITGYPTPVS----KWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTL 1193

Query: 1850 PYTSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
               +D K   G+     +  PS P++F V E T + V L W  P+ +GGSP+T Y +E +
Sbjct: 1194 QLENDVKSVSGEIEVNVIAAPSAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKR 1253

Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHAT 1964
             V  K+W K+VT G    E  + ++ E  E +F++SA N  G   P    + V +   AT
Sbjct: 1254 DVSRKTWVKVVT-GIQDQEFTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPAT 1312

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
            +P PP   L  R   ++ +  +W  P++DGG+ + GYNI         W   G + V   
Sbjct: 1313 IPDPP-ENLRWRDKSASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDL-VPET 1370

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
            K  +  L+E   Y  R+ A N +G S+P ++ +  + +
Sbjct: 1371 KLKVTGLTEGQWYAYRVRALNRLGASQPCKATDEIQAV 1408



 Score =  156 bits (379), Expect = 5e-36
 Identities = 197/853 (23%), Positives = 341/853 (39%), Gaps = 68/853 (7%)

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKRGSDVTLL 1308
            +L+I+ C    Q  YT    +     +  + VEV++ P P  + +  E      +D   L
Sbjct: 4161 SLVIKNCKRQHQGIYTLSAKNEGGERRKAVIVEVLDVPGPVGLPFAGE---NLTNDSCKL 4217

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT-----IKKVENTDAGIYKLRLE 1363
              Y   P+ N    + + II+K +  +    S S ++T     ++ + +     +++  E
Sbjct: 4218 TWYS--PEDNGGSAITNYIIEKRESDRMGWTSVSYTVTRNNAVVQGLLDGKGYFFRIAAE 4275

Query: 1364 NNCGHA---DVEMNVTILDKPSPPGKPNILEIDS---SSINICWDEPENTGNSTIIYYVV 1417
            N  G     + +  V I D  S P +P  L I +   +SI++ W  P+  G + +  YV+
Sbjct: 4276 NIIGMGPFIETDKMVLIKDPISVPERPEDLIISAVTKTSISVAWMPPKYDGGAEVTEYVL 4335

Query: 1418 EYQEIDTTEWISVKNITK---TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            E + I    ++ V   TK    + ++  LK  SS+ FR  AVN+V     S  T+   V 
Sbjct: 4336 ESRTIGRDNFVRVGGDTKLMDRKFTLSGLKEGSSHEFRVSAVNQVGQGKPSFATK--PVQ 4393

Query: 1475 KETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
             + +++ PT+E  +++ +  +  +   L+  FGG P P ++W ++ ++LK  +    +  
Sbjct: 4394 CKDELEPPTLELDIRDKMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHST 4453

Query: 1534 XXXXXXXXXXXXXXYK---CI-AFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKV 1586
                          +    C+   N  G    +C   VV   Q P   +   ++ + + V
Sbjct: 4454 ASHLSLTIAKARRDHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVFNEVYRNYMV 4513

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
               W       G      I  K       D    +T+    +  ++ +L         I 
Sbjct: 4514 -ISWNPPLDDGGCAISNYIIEKRDT--NRDLWMPVTSSCTRTTCKVPKLIEGREYIIRIM 4570

Query: 1647 ASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
            A N  G S    S E   + +Y  P  P+ P ++ E+  +S  I W+PP  DGG  +T Y
Sbjct: 4571 AQNIYGISDPLESAETKARDIYKVPDAPKQPTVL-EVYHDSALISWEPPA-DGGKPITGY 4628

Query: 1702 AIEKHEPDNNRWIK--VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758
             IE+ E   NRW++     +   VE Y +  L + CEY FRV A+N VG  + +  S+PI
Sbjct: 4629 IIERKETMANRWVRCNTERIHPKVE-YWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPI 4687

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXX 1817
              K  +  P              ESV ++W P    G   I  Y +E ++ G ++W    
Sbjct: 4688 FAKDPIVKPG-PPVNLKVIDFSKESVTLSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVN 4746

Query: 1818 XX----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                       ++  L       FR+ A N  G S P    + + +   L PP      +
Sbjct: 4747 HTPDSCQETKFKVINLEEGALCNFRVMAVNAAGESEPAYLREAVRVQDRLEPP----ELI 4802

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYI----IEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
            +    +R V       ++  G+ IT       + F TV  K     V     +     ++
Sbjct: 4803 LDAGMTREV-------KAMAGTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDS 4855

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
              E          + T+ V  P  S++            P   L +  V S+    SW  
Sbjct: 4856 KLEIRFCNREDCGDYTLTVENPAGSKTATCTVLVLDKPGPIQHLRVSDVRSDSAYLSWKD 4915

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            PE +GGA +  + +  +D   T W+ V           ++ L E  +Y  R+ A N+ G 
Sbjct: 4916 PEDNGGARITNFVVEKKDTASTQWVPVCSTS-KKRSMMLKHLMEGTSYSFRVAAENQYGR 4974

Query: 2050 SEPLESDEPFKVI 2062
            SE +E+ +  K +
Sbjct: 4975 SEYVETPKAIKAM 4987



 Score =  151 bits (366), Expect = 2e-34
 Identities = 167/718 (23%), Positives = 281/718 (39%), Gaps = 50/718 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKT 1436
            PS P  P I +    S+ + W  PE  G S I  Y+++ Q+   ++W+ V +       T
Sbjct: 3281 PSMPAAPEIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVNDPDTLHPTT 3340

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN---ITT 1493
            + ++ +L+    +RFR  AVN+V  SD S  T   +V+ E     P++   +     +  
Sbjct: 3341 EFTVPSLRELKRHRFRIIAVNDVGESDPSPRTG--EVLVEDIQLPPSISIDVTADDLLCI 3398

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
               + I +     G P PKVTW  DGK     K                        ++ 
Sbjct: 3399 RAGDPIRIPATIKGRPAPKVTWDFDGKAKSHKKNKLHTLPVDSEVESTDTTSVVIVPVSL 3458

Query: 1554 NDH-GEVETSCVVGIQQK----PVITISNEDIKQKHKVGDEWLVTA-VIEGIPPPE---- 1603
              H G    +      QK     VI +      +  KV D    T  +I  +P  +    
Sbjct: 3459 RTHSGRYTITAKNKSGQKHVNVRVIVLDVPGPPKDLKVTDITRSTVRLIWKLPESDGGER 3518

Query: 1604 VIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK- 1661
            +  Y    K   DK +  +     +    +  L       + + A N  G      T + 
Sbjct: 3519 IKSYFIEKKCITDKAWTKVNAACASQAYVVPGLLEGQDYLFRVRAENRLGFGPFTTTTEP 3578

Query: 1662 --VYDKPSKPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN-----R 1712
                D    P+ P  ++   +++ +VT+ W+ P ++GG  +T Y IE+   D +      
Sbjct: 3579 AHARDPIYPPDPPTKLKVNLVTKNTVTLSWECPKNNGGSPVTHYIIERLSWDTSGKEKET 3638

Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK--TALDVPSX 1769
            W +    D +  ++ ++ L E  EY FR+ A N  G S  +  + P+VIK  T   +   
Sbjct: 3639 WKQCNKRDVEELSFVVEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVIKDQTFAPIIEL 3698

Query: 1770 XXXXXXXXXIDNESV-YITWFP----SEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA 1824
                      D   V  ++  P    + +   +   + KV I  + +             
Sbjct: 3699 RESMEGEEGCDVSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYD-QHINKLVNQDKCTL 3757

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
             IQ+   + +  + + A N +G+    T D K+++     PP  P  F  +E  +  + L
Sbjct: 3758 LIQQACRSDSAIYSLTASNSVGS---VTKDIKLSVFGPPGPPVGPVKF--TEVFAERIGL 3812

Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
             W  P  +GGS IT+Y++E +    KSW   V+         +  + E  E  FRI A+N
Sbjct: 3813 AWNPPTDDGGSKITSYVVEKREDNRKSWVH-VSDDPKECAFVVTRLTENHEYEFRIMAQN 3871

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
              GV  P  S   +     TVP     P  +  V    +  +W  P++DGG+P+ GY I 
Sbjct: 3872 KFGVGPPLLSDPEKARNLFTVPGQCEKP-TVTEVCLESMTVNWEEPKYDGGSPVTGYFIE 3930

Query: 2005 IRDVTKTMWMEVGKVDVNTL----KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             ++ T   W  V +  +  L     +++  L E   Y  R+ A N  G   P    +P
Sbjct: 3931 KKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAMYQFRVIAANAAGCGLPSMPSDP 3988



 Score =  149 bits (362), Expect = 6e-34
 Identities = 86/283 (30%), Positives = 135/283 (47%), Gaps = 5/283 (1%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQ 1836
            I   S  + W   E++GGSPI +Y VE +   +K W+            +  L+  + Y 
Sbjct: 1847 ISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAVDTTVKELIYTVTPLNEGSLYV 1906

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR+ A N +G        D +    T T P  P    V   T R V L+W  P+++GG P
Sbjct: 1907 FRVAAENAVGVGPFCELTDSVLAKDTFTTPGPPYALAVVAVTKRYVDLQWEAPKNDGGRP 1966

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955
            I  Y IE K   G  W K     G   ++ + ++ E  E+ F++SAEN  G+  P+E ++
Sbjct: 1967 ILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTE 2026

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
             + +E    VPSPP   L +     + +  +W  P  DGG P+ GY+I + +     WM 
Sbjct: 2027 ILTIEDPTGVPSPPVE-LHVTGASRDFLAVAWKPPLRDGGCPISGYHIEMCEAGTEKWMR 2085

Query: 2016 VGKVDVNTLKFNIRD-LSENHTYMIRIYARNEIGLSEPLESDE 2057
            V    V  LK+ + + +     Y++R+ A N +G+SEP +  E
Sbjct: 2086 VNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEPSDISE 2128



 Score =  147 bits (356), Expect = 3e-33
 Identities = 166/687 (24%), Positives = 272/687 (39%), Gaps = 55/687 (8%)

Query: 1346 TIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDK---PSPPGKPNILEIDSSSI 1397
            TIK  + T+   Y+ R+   N  G    +D       +D    P PP  P +++   SSI
Sbjct: 7081 TIKASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPVYPPGPPAFPKVVDSTRSSI 7140

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454
            ++ W +P   G   II Y+VE +  +  +W      K +  T+  + +L  N+ Y+FR  
Sbjct: 7141 SLSWTKPAYDGGCEIIGYLVECKRAEAEDWTKCNVPKKLQATKFLVTSLMDNTEYQFRVS 7200

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKV 1513
            A+N++  S+ S+    +            ++  L K +       + L     G P PKV
Sbjct: 7201 ALNKIGFSEPSDVPGNHMPKDILLPPEAELDADLRKALVLRAGVTMRLYVPVRGRPAPKV 7260

Query: 1514 TWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            TW +    LK  +     T E                 Y  +  N  G    + VV +  
Sbjct: 7261 TWTKVNYNLKERQGLLINTSEWDTLLMVEDINRYDAGKYVLMLENSSGSKSYTIVVKVLD 7320

Query: 1570 KPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-- 1625
             P   + N  +K+  +    W+     +I+G  P  V  Y    +L   K +   + E  
Sbjct: 7321 SPGPPV-NLTVKETTR-NQAWITWDAPLIDGGSP--VKSYVVEKRLAERKAWTCVSAECP 7376

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVI---MREISRE 1681
            KTS  RI  L+   +  + + A N  G     E    V  + S+  GPV     ++ ++ 
Sbjct: 7377 KTS-FRILNLEAGQAYCFRVLAENNYGIGEGCETPGSV--RASEQPGPVTDFKAQKTTKN 7433

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
            SVT+ WK P+ DGG  +T Y +E  E ++ +W ++        T  + +L E  EY FRV
Sbjct: 7434 SVTLAWKKPISDGGSYITAYVLELSEGED-KWKQIKKGKEASHT--MSELTEGKEYTFRV 7490

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
             A N  G     E   ++ K    +P             +++ YI    S      P+I 
Sbjct: 7491 RALNESGEGPPTELT-VMAKDQFVLPDCNLSGL------HDNCYIVKEGSTTRINIPVIG 7543

Query: 1802 YKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGT------SLPYTS 1853
                +      WK          R  ++     TT   R   R +  T      +   + 
Sbjct: 7544 ----VPYPTALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTYTINVRNSAGSK 7599

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
            D K ++     P          E T+  +TL+W  P+ +GG+ ++NYI+E +      W 
Sbjct: 7600 DCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAEVSNYIVEKRRTTDNKWA 7659

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973
             + +         I  ++E  E IFR+ AEN  GV     S+ V  +    VP  P AP 
Sbjct: 7660 TVASAIQKTSMRVIR-LQEGKEYIFRVFAENKYGVGEYLRSEPVIAQHPFNVPGAP-APP 7717

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            EI  +     + +W  P+  GG+P+ G
Sbjct: 7718 EIVSIRHESAILTWADPKDTGGSPITG 7744



 Score =  146 bits (354), Expect = 6e-33
 Identities = 105/375 (28%), Positives = 171/375 (45%), Gaps = 28/375 (7%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKY 1643
            + G + +V A++ G P P   W K GN+     E     K  TS  + IK + R+ S  Y
Sbjct: 6460 RAGSKMVVEAIVAGKPAPFCKW-KQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYY 6518

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
            ++ A N+ G ++  + + V D P  PE P+ + E   ++ T+ W  P +DGG  +T Y I
Sbjct: 6519 SLSAENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYII 6578

Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            EK +     W+ V+       ++ + KL    EY FRV A+N  G SE + SE I+ +  
Sbjct: 6579 EKCDISQGDWVTVSS-SCTKTSFRMTKLIPGKEYGFRVRAENRFGISEPIYSERIIARYP 6637

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
             D PS          I+ + V ++W     +GGSPI  Y +E K+     W         
Sbjct: 6638 FDPPS-EPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVK 6696

Query: 1823 XAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
              +     L     Y FR+ A N  G                  PP +P    V++S   
Sbjct: 6697 ATQYTCSGLIEGLEYTFRVSALNLAGQD----------------PPGKPEPMDVTKS--- 6737

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEKDEIIF 1938
            SV+L W+ P+ +GGS +  Y +E+  + G+ WT+  T  +      + +  ++E  +  F
Sbjct: 6738 SVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESYVVTGLEEGQQYQF 6797

Query: 1939 RISAENTVGVSLPTE 1953
            R+ A+  + VS+ +E
Sbjct: 6798 RVIAKTAINVSMASE 6812



 Score =  140 bits (339), Expect = 4e-31
 Identities = 108/411 (26%), Positives = 176/411 (42%), Gaps = 19/411 (4%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD--RDV 1723
            PS P  P I  + ++ SVT+ WKPP  DGG  +  Y I+  +   + W++V D D     
Sbjct: 3281 PSMPAAPEIADK-TKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVNDPDTLHPT 3339

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
              + +  L E   + FR+IA N VG S+ +  +  ++++     PS          +   
Sbjct: 3340 TEFTVPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVEDIQLPPSISIDVTADDLLCIR 3399

Query: 1783 SVYITWFPSEKNGG-SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
            +      P+   G  +P + +  + K +  K K         + ++     +     +  
Sbjct: 3400 AGDPIRIPATIKGRPAPKVTWDFDGKAKSHK-KNKLHTLPVDSEVESTDTTSVVIVPVSL 3458

Query: 1842 RNEIG----TSLPYTSDDKITIGK-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            R   G    T+   +    + +    L  P  P++  V++ T  +V L W  PES+GG  
Sbjct: 3459 RTHSGRYTITAKNKSGQKHVNVRVIVLDVPGPPKDLKVTDITRSTVRLIWKLPESDGGER 3518

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQ 1955
            I +Y IE K +  K+WTK+     S   + +  + E  + +FR+ AEN +G     T ++
Sbjct: 3519 IKSYFIEKKCITDKAWTKVNAACAS-QAYVVPGLLEGQDYLFRVRAENRLGFGPFTTTTE 3577

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-----IRDVTK 2010
                      P PPT  L++ +V  N V  SW  P+ +GG+P+  Y I           K
Sbjct: 3578 PAHARDPIYPPDPPT-KLKVNLVTKNTVTLSWECPKNNGGSPVTHYIIERLSWDTSGKEK 3636

Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
              W +  K DV  L F + DL E   Y  RI A N  G S P  +  P  +
Sbjct: 3637 ETWKQCNKRDVEELSFVVEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVI 3687



 Score =  139 bits (336), Expect = 9e-31
 Identities = 116/470 (24%), Positives = 193/470 (41%), Gaps = 17/470 (3%)

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
            ++   I G P P   W     +L   D+   +T K   + + +    R     YT++  N
Sbjct: 1138 VIRVPITGYPTPVSKWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLEN 1197

Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
               + S E+ + V   PS P+   ++ E++R+ V + W+ P  DGG  LT Y +EK +  
Sbjct: 1198 DVKSVSGEIEVNVIAAPSAPKDFKVL-EVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVS 1256

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768
               W+KV    +D E + +  + E  EY+F+V A N  G  E A   EP+ I +   +P 
Sbjct: 1257 RKTWVKVVTGIQDQE-FTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPD 1315

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-XXXARI 1826
                          S+++TW P + +GGS I  Y ++  Q G  KW+           ++
Sbjct: 1316 PPENLRWRDK-SASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKV 1374

Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
              L+    Y +R+ A N +G S P  + D+I       PP    +  +    +     K 
Sbjct: 1375 TGLTEGQWYAYRVRALNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKI 1434

Query: 1887 TEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
              P    G   P   +      +K      I T  G      I   K  D   + I A N
Sbjct: 1435 ELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGH-STVTIAKTKRDDSSTYIIEATN 1493

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
            + G +  T   ++ L+K    P PP A  +I  + ++    +W  P  DGG+ +  Y + 
Sbjct: 1494 SCGRATATVDVNI-LDK----PGPPAA-FDISEITNDSCFLAWNPPRDDGGSRVTNYIVE 1547

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
             R     +W  +    V    +    L +   Y+ R++A N+ G+  P E
Sbjct: 1548 RRAADSEIWHRLSST-VKQTTYRAAGLVKFKEYIFRVFAENQFGVGTPAE 1596



 Score =  137 bits (332), Expect = 3e-30
 Identities = 134/567 (23%), Positives = 243/567 (42%), Gaps = 39/567 (6%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            E P E    L++Q V +   AT E E+++ +A V W +DG EI+ +   ++ IDG+K+ L
Sbjct: 7    EPPVEFTKPLEDQTVEEEATATLECEVSRENADVLWLRDGQEIRKTKKYEMVIDGRKRAL 66

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
             I+DC LDD+  Y+C   + K +  LTVE P + FT  L + + V     A    E+  E
Sbjct: 67   VIHDCTLDDSRTYTCGAKDFKTSCFLTVEPPHVEFTKPLHD-VEVREKESARFECEVSRE 125

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV-- 1281
             + V W+K  S I   +K+ +I+  ++  LI+ K   DD+ EY C    +KS+  L V  
Sbjct: 126  NIKVRWFKDGSEIRKGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDAKTSKSSGMLTVIE 185

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            E   F   +   E   R     D   L+   + P  +  W    + + +    +  +D K
Sbjct: 186  EEARFTKNLSHVEAAER-----DSVKLICEVSKPDADVSWFKGDEELPEGGRYEHIVDGK 240

Query: 1342 SASLTIKKVENTDAGIYKLRLENNC-GHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
               L I+ ++  DAG Y  RL         +++N    +  S P    ++E    ++  C
Sbjct: 241  RRILLIRDLKMADAGEYNCRLSPAIKTSGSLKVNELAAEFISKPCSQEVVE-GEKAVFTC 299

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--LKTNSSYRFRAYAVNE 1458
                E      + ++  + +  D  ++  V +  K    I+N  LK  S Y         
Sbjct: 300  IVSKE---TFEVKWFKGDKELEDGDKYQMVSDGKKRTLVIKNCELKDESGY--------- 347

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            V I   ++ +   KV+++ KI +     PLK+      +++ L C        K  W ++
Sbjct: 348  VVIIGVTKASADLKVLEKLKIIT-----PLKDTEAIEGDEVVLNC-EANTDGAKAKWLQN 401

Query: 1519 GKKL-KTAKATYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVET-SCVVGIQQKPV- 1572
            G+ L +++K     R                  +     N  GE  T SC + ++++ + 
Sbjct: 402  GETLFESSKCVMVQRDSVFSLRIRNVHKGDEANFSISLTNQRGEQATSSCSLTVKEESLR 461

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            I +  EDI  + K   + +  +     P   + W K+G ++  +K           ++ I
Sbjct: 462  IIVPLEDIDTQEK---KTVSFSCKVNRPNATLKWLKSGEEVTFNKRLVYRVDVDKHILTI 518

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVT 1659
            K+   +   +YT  A ++  T+ + ++
Sbjct: 519  KDCTLADEGEYTAIAGDSKSTAELIIS 545



 Score =  131 bits (316), Expect = 2e-28
 Identities = 129/496 (26%), Positives = 200/496 (40%), Gaps = 32/496 (6%)

Query: 1643 YTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLE 1697
            + + A N  G    + + K Y   D  S+P+ P  M   EI++ S T+ W  PL DGG +
Sbjct: 6319 FRVMACNKYGIGVPQDSPKSYLAVDPISEPDPPKKMDVLEITKNSATLGWLKPLRDGGAK 6378

Query: 1698 LTKYAIEKHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            +  Y ++  E  +  ++W   + V +D+ T  +  LNE  +Y FRV A+N VG   A E+
Sbjct: 6379 INGYVVDYQEEGSPEDKWTPYSVV-KDL-TIVVVGLNEGKKYKFRVAARNSVGVGLAREA 6436

Query: 1756 EPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV--EIKQEGKK 1812
            E +  IK  L  P             ++ V       +    +P   +K   E     ++
Sbjct: 6437 EGVFEIKERLMAPKIIMPDIVTVRAGSKMVVEAIVAGKP---APFCKWKQGNEDVLTSER 6493

Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                         I+ ++   +  + + A N  G +       ++T+     PP  P   
Sbjct: 6494 LSVVKTLTSCTLIIKHVTRADSGYYSLSAENSTGKANQIL---RVTVMDIPGPPEAPLE- 6549

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK- 1931
             ++E    + TL W  P+ +GGS ITNYIIE   +    W   VTV  S  +      K 
Sbjct: 6550 -ITEQDIDACTLLWNSPQEDGGSNITNYIIEKCDISQGDW---VTVSSSCTKTSFRMTKL 6605

Query: 1932 -EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
                E  FR+ AEN  G+S P  S+ +        PS P   L+I  +  + V+ SW  P
Sbjct: 6606 IPGKEYGFRVRAENRFGISEPIYSERIIARYPFDPPSEPQN-LQINKINKDFVILSWERP 6664

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
              DGG+P+ GY I  ++    +W+   +  V   ++    L E   Y  R+ A N  G  
Sbjct: 6665 NSDGGSPITGYCIERKERNSLLWVRANESVVKATQYTCSGLIEGLEYTFRVSALNLAG-Q 6723

Query: 2051 EPLESDEPFKVIPGEGSHADEEP---GEQTEVXXXXXXXXXXXXXWLR--EHNMDADIRS 2105
            +P    EP  V     S     P   G    +             W R   + MD    S
Sbjct: 6724 DPPGKPEPMDVTKSSVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTES 6783

Query: 2106 YARGSLLRRDEYFFRI 2121
            Y    L    +Y FR+
Sbjct: 6784 YVVTGLEEGQQYQFRV 6799



 Score =  124 bits (299), Expect = 3e-26
 Identities = 69/227 (30%), Positives = 112/227 (49%), Gaps = 9/227 (3%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            +++  +N  G    + S D I +      P   RN  V ++    V+L W EPE++GGS 
Sbjct: 793  YKVIIKNTHGEGEAFISLDVIDV------PGPVRNLQVVDTADGEVSLTWEEPENDGGSK 846

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            +T Y++E + VK K+WT +VT      E+ +  ++     +FR+ A N VG     E+  
Sbjct: 847  VTGYVLERRDVKRKTWT-LVTDQAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNVETDK 905

Query: 1957 -VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
             V+ +    VP  P   + +  V       SW  PEWDGG+P+  Y + +RD T   W  
Sbjct: 906  PVQAKNKFDVPDAPLNVI-VGDVSKFGCTVSWERPEWDGGSPITSYIVELRDRTSVKWSS 964

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
            V     + L   I D+ EN  Y+ R+ A N+ G+ +P  + +P K++
Sbjct: 965  VHVTTADELSAIINDVIENKEYIFRVRAENKAGVGKPSAASQPVKIM 1011



 Score =  124 bits (298), Expect = 4e-26
 Identities = 157/703 (22%), Positives = 268/703 (38%), Gaps = 59/703 (8%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITK 1435
            + +P PP K ++LEI  +S  + W +P   G + I  YVV+YQE  + E  W     +  
Sbjct: 6345 ISEPDPPKKMDVLEITKNSATLGWLKPLRDGGAKINGYVVDYQEEGSPEDKWTPYSVVKD 6404

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
                +  L     Y+FR  A N V +  A E    ++ IKE ++ +P +  P   +T   
Sbjct: 6405 LTIVVVGLNEGKKYKFRVAARNSVGVGLAREAEGVFE-IKE-RLMAPKIIMP-DIVTVRA 6461

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXX----XXXXXXXXXXXYKCI 1551
               + +  I  G P P   W +  + + T++     +                   Y   
Sbjct: 6462 GSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYYSLS 6521

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            A N  G+      V +   P    +  +I ++       L  +  E        +     
Sbjct: 6522 AENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYIIEKC 6581

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPE 1670
             +       +++    +  R+ +L       + + A N  G S    + ++  + P  P 
Sbjct: 6582 DISQGDWVTVSSSCTKTSFRMTKLIPGKEYGFRVRAENRFGISEPIYSERIIARYPFDPP 6641

Query: 1671 GPVIMREISR---ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
                  +I++   + V + W+ P  DGG  +T Y IE+ E ++  W++  +       Y 
Sbjct: 6642 SEPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVKATQYT 6701

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
               L E  EY FRV A N  G     + EP+                    +   SV + 
Sbjct: 6702 CSGLIEGLEYTFRVSALNLAGQDPPGKPEPM-------------------DVTKSSVSLV 6742

Query: 1788 WFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX----XXXXXARIQKLSINTTYQFRIYAR 1842
            W   + +GGS +I Y +E  K  G+KW                +  L     YQFR+ A+
Sbjct: 6743 WSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESYVVTGLEEGQQYQFRVIAK 6802

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPS-----QPRNFVVSESTSRSVTLKWTEPESNGGS-P 1896
              I  S+     D I +     PP        +N +V ++   +V L   + E  G   P
Sbjct: 6803 TAINVSMASELSDPIPVIAENVPPRVDLGINMKNLIVVKA-GENVFL---DAEVFGKPLP 6858

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTES 1954
               +  +   +      K+V      H H +E  ++  K+   + I AEN  G    T  
Sbjct: 6859 KVTWKRDGIPLVLAEGMKMVQ---KKHVHLLELYSVTRKETGDYTILAENINGSKYATIK 6915

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW- 2013
              V L+K    P PP A ++   V S+ V   W  P  DGG+ +  Y I  R+ ++  W 
Sbjct: 6916 VKV-LDK----PGPP-ASVKTTKVFSDRVKLRWEPPLADGGSEITNYIIEKRETSRANWA 6969

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
            +    +  +    ++  L E H Y  R+ A N+ G+ +P  +D
Sbjct: 6970 LVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYGVGDPAMTD 7012



 Score =  123 bits (296), Expect = 6e-26
 Identities = 110/446 (24%), Positives = 181/446 (40%), Gaps = 20/446 (4%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P  PE  +  R+ S  S+ + W+PP  DGG  +  Y I++ +   ++W    D+  + + 
Sbjct: 1314 PDPPEN-LRWRDKSASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKL 1372

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
              +  L E   Y +RV A N +G S+  ++ + I      + P           +  ++ 
Sbjct: 1373 K-VTGLTEGQWYAYRVRALNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAG 1431

Query: 1785 YITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
                 P+E  G   P + + K + + +   +             I K   + +  + I A
Sbjct: 1432 SKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYIIEA 1491

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             N  G +   T D  I     L  P  P  F +SE T+ S  L W  P  +GGS +TNYI
Sbjct: 1492 TNSCGRATA-TVDVNI-----LDKPGPPAAFDISEITNDSCFLAWNPPRDDGGSRVTNYI 1545

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            +E +    + W ++ +            +K K E IFR+ AEN  GV  P E  S+    
Sbjct: 1546 VERRAADSEIWHRLSSTVKQTTYRAAGLVKFK-EYIFRVFAENQFGVGTPAEHPSIIARY 1604

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                P  P   L+   V  + V  SW  P+ DGG+P+ GY +   +     W+   K+ +
Sbjct: 1605 PFDTPGAPYN-LQPSDVAKDSVNLSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPI 1663

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXX 2081
                + ++ L+    Y  R+ A N  G  +P  S E   ++  +       PG+ T    
Sbjct: 1664 KDTNYKVKGLATRKKYKFRVLAENLAGTGKP--SKETDLILVKDPIDPPWPPGKPT---V 1718

Query: 2082 XXXXXXXXXXXWLR-EHNMDADIRSY 2106
                       W + EH+  A I SY
Sbjct: 1719 KDVAKTSCFLMWTKPEHDGGAKIDSY 1744



 Score =  121 bits (292), Expect = 2e-25
 Identities = 77/282 (27%), Positives = 121/282 (42%), Gaps = 4/282 (1%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXXXARIQKLSINTTYQ 1836
            I N+S ++ W P   +GGS + +Y VE +  + + W +          R   L     Y 
Sbjct: 1521 ITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQTTYRAAGLVKFKEYI 1580

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR++A N+ G   P      I        P  P N   S+    SV L W EP+ +GGSP
Sbjct: 1581 FRVFAENQFGVGTP-AEHPSIIARYPFDTPGAPYNLQPSDVAKDSVNLSWYEPDEDGGSP 1639

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            IT Y +E    +   W +   +      + ++ +  + +  FR+ AEN  G   P++   
Sbjct: 1640 ITGYWVERYEPEHDKWIRCNKLPIKDTNYKVKGLATRKKYKFRVLAENLAGTGKPSKETD 1699

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
            + L K    P  P     ++ V        W  PE DGGA +  Y + +       W+ V
Sbjct: 1700 LILVKDPIDPPWPPGKPTVKDVAKTSCFLMWTKPEHDGGAKIDSYVVEMLKSGTVDWIRV 1759

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               +V+ L++ ++ L E   Y  R+ A N  G SEP E  +P
Sbjct: 1760 VD-NVSLLEYFLKGLMEKQEYSFRVRAVNVAGESEPSEPSDP 1800



 Score =  121 bits (291), Expect = 3e-25
 Identities = 86/321 (26%), Positives = 146/321 (45%), Gaps = 9/321 (2%)

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
            D PS P    ++  ISR S  ++W  P  DGG  +T Y +EK +     W  V    +++
Sbjct: 1834 DPPSAPRWLDVVN-ISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAVDTTVKEL 1892

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
              Y +  LNE   Y+FRV A+N VG     E ++ ++ K     P           +   
Sbjct: 1893 -IYTVTPLNEGSLYVFRVAAENAVGVGPFCELTDSVLAKDTFTTPG-PPYALAVVAVTKR 1950

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINTTYQFRI 1839
             V + W   + +GG PI+ Y +E K++ G +W             R+  +   T  QF++
Sbjct: 1951 YVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGTEVQFQV 2010

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             A NE G   P    + +TI      PS P    V+ ++   + + W  P  +GG PI+ 
Sbjct: 2011 SAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGASRDFLAVAWKPPLRDGGCPISG 2070

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCI-ENIKEKDEIIFRISAENTVGVSLPTE-SQSV 1957
            Y IE      + W ++ +      ++ + E +  + E I R+ A N+VGVS P++ S++V
Sbjct: 2071 YHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEPSDISENV 2130

Query: 1958 RLEKHATVPSPPTAPLEIRMV 1978
              ++    P+     L++ +V
Sbjct: 2131 FAKESDCNPALDFQTLDLVVV 2151



 Score =  119 bits (286), Expect = 1e-24
 Identities = 110/450 (24%), Positives = 192/450 (42%), Gaps = 30/450 (6%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREI--SRESVTI 1685
            R+ ++      ++ + A N AG    S     L + D    P  PV +     SR+ + +
Sbjct: 1996 RVTDVIEGTEVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGASRDFLAV 2055

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744
             WKPPL DGG  ++ Y IE  E    +W++V         Y +++ +    EY+ RV A 
Sbjct: 2056 AWKPPLRDGGCPISGYHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAI 2115

Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N VG SE  + SE +  K +   P+          ++ E ++I   P  +   SP    K
Sbjct: 2116 NSVGVSEPSDISENVFAKESDCNPALDFQTLDLVVVETEKLHIP-VPF-RAVPSP----K 2169

Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL-------PYTSDDK 1856
            V   ++GK+ K                     +       E+ +SL         T ++K
Sbjct: 2170 VTWHKDGKELKADERLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKVTLENK 2229

Query: 1857 I-----TIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
            +     TI  K +  P   ++ + SE T  S  + W  P+ +GGSP+ +Y+++ +    +
Sbjct: 2230 LGAASGTISVKVIGLPGPCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQRREAGRR 2289

Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPP 1969
            ++  +++ G +     ++++    E  FR+ A N +G     E ++ V  E     P PP
Sbjct: 2290 TYVNMMS-GENKVSWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNPVIAEDQKHAPDPP 2348

Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029
               +E     S+    +W  P +DGG  ++GY + ++      W       V  L + +R
Sbjct: 2349 V-DVETHNPTSSTTTLTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPVLSYTVR 2407

Query: 2030 DLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
             L E  +Y  R+ A N  G+SEP   + PF
Sbjct: 2408 GLKEGKSYTFRVKAENAAGVSEP-SRNTPF 2436



 Score =  113 bits (272), Expect = 5e-23
 Identities = 112/467 (23%), Positives = 187/467 (40%), Gaps = 43/467 (9%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            AVI G P P+V W + G  ++N  +  ++   +  S + I E  R  S KY++  SN+AG
Sbjct: 6203 AVIRGRPAPKVTWKRLG--VDNVIRRGHVDQVDTMSFLVIPESTREDSGKYSLHLSNSAG 6260

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
              +V V +KV +                           D G   +  Y +EK E D   
Sbjct: 6261 EKAVFVRVKVLEN--------------------------DGGS-PILNYIVEKREVDRKT 6293

Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772
            W K  + D    ++ +  +    EY FRV+A N  G     +S    +            
Sbjct: 6294 WTKCTE-DLKKTSFKVTNMTPGIEYYFRVMACNKYGIGVPQDSPKSYLAVDPISEPDPPK 6352

Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829
                  I   S  + W    ++GG+ I  Y V+ ++EG    KW            +  L
Sbjct: 6353 KMDVLEITKNSATLGWLKPLRDGGAKINGYVVDYQEEGSPEDKWTPYSVVKDLTIVVVGL 6412

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
            +    Y+FR+ ARN +G  L   ++    I + L  P      +V+      + ++    
Sbjct: 6413 NEGKKYKFRVAARNSVGVGLAREAEGVFEIKERLMAPKIIMPDIVTVRAGSKMVVE--AI 6470

Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
             +   +P   +    + V       +V    S     I+++   D   + +SAEN+ G +
Sbjct: 6471 VAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSC-TLIIKHVTRADSGYYSLSAENSTGKA 6529

Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
                +Q +R+     +P PP APLEI     +     W +P+ DGG+ +  Y I   D++
Sbjct: 6530 ----NQILRVTV-MDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYIIEKCDIS 6584

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
            +  W+ V      T  F +  L     Y  R+ A N  G+SEP+ S+
Sbjct: 6585 QGDWVTVSSSCTKT-SFRMTKLIPGKEYGFRVRAENRFGISEPIYSE 6630



 Score =  105 bits (252), Expect = 1e-20
 Identities = 76/269 (28%), Positives = 120/269 (44%), Gaps = 20/269 (7%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G+   + A + G P P + W  N  K + D+   I ++   S++ IK  +R    KY 
Sbjct: 2855 RAGEILRLPATVTGKPYPSITWTINDAKPDKDR-VEILSEGSNSIVEIKNAQRKDCGKYH 2913

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            I A N +GT      ++V D P  P   +    ++R+ + + W  P DDGG +LT + +E
Sbjct: 2914 ISACNPSGTKGASTRVEVVDVPG-PVTDLKPVVVTRKMIFLNWDDPEDDGGSDLTGFIVE 2972

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            + +   + W +  +     +  C+  + E  EYMFRVIA+N  G    +E  PI    A+
Sbjct: 2973 RRDAKMHTWRQPVET-ASSKCECV-GIMEGQEYMFRVIAKNKYGMGPPVELGPI---KAV 3027

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK---QEGKKWKXXXXXXX 1821
            D                 S+ + W P   +GGSP+I Y VE K   Q+  +         
Sbjct: 3028 DPQERT----------KNSITLAWKPPRNDGGSPVIGYFVEKKRQDQQAFEPCNTEICPN 3077

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLP 1850
                ++ L     Y+FRI   N IG S P
Sbjct: 3078 MTMTVEGLDDAWMYEFRIKCANLIGESEP 3106



 Score =  103 bits (248), Expect = 4e-20
 Identities = 113/462 (24%), Positives = 182/462 (39%), Gaps = 41/462 (8%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W  +G + E  K+ N    E+ S + +++L+     ++ I+A N AG S    T      
Sbjct: 3629 WDTSGKEKETWKQCNKRDVEELSFV-VEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVI 3687

Query: 1666 PSKPEGPVI-MREISRESVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVAD--- 1718
              +   P+I +RE        +        G     LT       +P+    I       
Sbjct: 3688 KDQTFAPIIELRESMEGEEGCDVSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYDQHIN 3747

Query: 1719 --VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
              V++D  T  IQ+   +   ++ + A N VG      ++ I + +    P         
Sbjct: 3748 KLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSV----TKDIKL-SVFGPPGPPVGPVKF 3802

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI-QKLSINTT 1834
              +  E + + W P   +GGS I  Y VE +++ +K W          A +  +L+ N  
Sbjct: 3803 TEVFAERIGLAWNPPTDDGGSKITSYVVEKREDNRKSWVHVSDDPKECAFVVTRLTENHE 3862

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y+FRI A+N+ G   P  SD +       T P Q     V+E    S+T+ W EP+ +GG
Sbjct: 3863 YEFRIMAQNKFGVGPPLLSDPE-KARNLFTVPGQCEKPTVTEVCLESMTVNWEEPKYDGG 3921

Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
            SP+T Y IE K    K WT++    +      +   +  + E     FR+ A N  G  L
Sbjct: 3922 SPVTGYFIEKKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAMYQFRVIAANAAGCGL 3981

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
            P+      L +    P  P  P  I    S++ +  W  P  DGG+              
Sbjct: 3982 PSMPSDPILCRDPIKPPGPPTPKVIDWTRSSVEL-EWIPPLLDGGS-------------- 4026

Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                +V   ++   KF +  L E   Y  R+ A N  G+ EP
Sbjct: 4027 ----KVKDTEIRGTKFVVAGLKEGGLYRFRVRAVNAAGVGEP 4064



 Score =   99 bits (238), Expect = 7e-19
 Identities = 103/474 (21%), Positives = 192/474 (40%), Gaps = 31/474 (6%)

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPS--KPEGPVIMR- 1676
            + T  K  +  +  L       + + A N  G     E+T  V  K +   P  P  +  
Sbjct: 1885 VDTTVKELIYTVTPLNEGSLYVFRVAAENAVGVGPFCELTDSVLAKDTFTTPGPPYALAV 1944

Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
              +++  V ++W+ P +DGG  + +Y+IEK E    RW+K          Y +  + E  
Sbjct: 1945 VAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGT 2004

Query: 1736 EYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
            E  F+V A+N  G     E +E + I+    VPS             + + + W P  ++
Sbjct: 2005 EVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGA-SRDFLAVAWKPPLRD 2063

Query: 1795 GGSPIIDYKVEIKQEG-KKWKXXXX--XXXXXARIQKLSI-NTTYQFRIYARNEIGTSLP 1850
            GG PI  Y +E+ + G +KW             R+++  +    Y  R+ A N +G S P
Sbjct: 2064 GGCPISGYHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEP 2123

Query: 1851 YTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPES-------NGGSPITNY 1900
                + +   ++   P+   Q  + VV E+    + + +    S       +G     + 
Sbjct: 2124 SDISENVFAKESDCNPALDFQTLDLVVVETEKLHIPVPFRAVPSPKVTWHKDGKELKADE 2183

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
             + F          +         H  +++    D   ++++ EN +G +  T S  V  
Sbjct: 2184 RLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKVTLENKLGAASGTISVKV-- 2241

Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
                 +P  P   +    +  +    SW  P++DGG+P++ Y +  R+  +  ++ +   
Sbjct: 2242 ---IGLPG-PCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQRREAGRRTYVNMMSG 2297

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
            + N + + ++DL     Y  R+ A N+IG  E +E   P  VI  +  HA + P
Sbjct: 2298 E-NKVSWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNP--VIAEDQKHAPDPP 2348



 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 78/300 (26%), Positives = 126/300 (42%), Gaps = 25/300 (8%)

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXX 1819
            + LDVP           I  +   + W   E +GG  +  Y +E K E ++  W      
Sbjct: 5872 SVLDVPGPVRNLRLTG-IGADKCRVVWDAPEDDGGCEVDSYILE-KCETRRMVWSTYSAS 5929

Query: 1820 XXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   + +L     Y FR+ A N++GT  P T    +T+      P  P    V++ +
Sbjct: 5930 VVTPYCNVIRLVEGNEYIFRVRAENKMGTG-PATETKPVTVKTQFNKPGPPDPPEVTKVS 5988

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
               +T+ W  PE++GG  IT YI+E K  +   W        S     + N+    E  F
Sbjct: 5989 KDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNKSPISERRMKVSNLIPNHEYQF 6048

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGA 1996
            R+ AEN VG+  P++            P     P+ +++  S    +  SW  P +DGGA
Sbjct: 6049 RVKAENEVGLGEPSKPSR---------PIAAKDPIGLKVSDSTKTSITLSWSKPVYDGGA 6099

Query: 1997 PLLGYNIAIR-----DVTKTM--WMEVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIG 2048
            P++GY++ +R     D  K    W  +       L +F I  L E   Y  ++ A+N++G
Sbjct: 6100 PIIGYSLDLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKEYEFKVSAQNQVG 6159



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 69/285 (24%), Positives = 126/285 (44%), Gaps = 20/285 (7%)

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITT------------KEKTSV-IRIKELKRSHSSKYTI 1645
            +P P+V W+K+G +L+ D+  + +             KE TS  + +     + + +Y +
Sbjct: 2165 VPSPKVTWHKDGKELKADERLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKV 2224

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
               N  G +S  +++KV   P  P   ++  EI++ S  + W PP  DGG  +  Y +++
Sbjct: 2225 TLENKLGAASGTISVKVIGLPG-PCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQR 2283

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764
             E     ++ +   +  V ++ ++ L    EY FRV A N +G  E +E   P++ +   
Sbjct: 2284 REAGRRTYVNMMSGENKV-SWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNPVIAEDQK 2342

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK--XXXXXXX 1821
              P             + +  +TW P   +GG  I+ Y +E++Q+G  KW+         
Sbjct: 2343 HAPDPPVDVETHNPTSSTTT-LTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPV 2401

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
                ++ L    +Y FR+ A N  G S P  +   I     + PP
Sbjct: 2402 LSYTVRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPP 2446



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 87/329 (26%), Positives = 143/329 (43%), Gaps = 28/329 (8%)

Query: 1156 IDGKKQKLKIYDCDLDDAGE--YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
            I+GK+   K+  C+    GE  Y  E  N    A  T+ +P  N   R        + + 
Sbjct: 1278 IEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPA--TIPDPPENLRWR------DKSASS 1329

Query: 1214 AYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVL 1270
             +LT E P  D    +  Y        T+K+    D+   T L +   TE     Y    
Sbjct: 1330 IFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKVTGLTEGQWYAYRVRA 1389

Query: 1271 LD-------AKSTTKLKVEVVEFPPKI-VDYE--REYRIKRGSDVTLLVDYQAFPQPNDE 1320
            L+        K+T +++    + PP+I +D +       K GS + L  + +  P+P  +
Sbjct: 1390 LNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGKPEPRVK 1449

Query: 1321 WIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
            W     ++K     + SID+K   +++TI K +  D+  Y +   N+CG A   ++V IL
Sbjct: 1450 WTKADLVLKP--DDRISIDTKPGHSTVTIAKTKRDDSSTYIIEATNSCGRATATVDVNIL 1507

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            DKP PP   +I EI + S  + W+ P + G S +  Y+VE +  D+  W  + +  K  T
Sbjct: 1508 DKPGPPAAFDISEITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQTT 1567

Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASE 1466
                 L     Y FR +A N+  +   +E
Sbjct: 1568 YRAAGLVKFKEYIFRVFAENQFGVGTPAE 1596



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 72/279 (25%), Positives = 127/279 (45%), Gaps = 15/279 (5%)

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELK 1636
            ED +++ K G+E   T   E  P PE    ++     N++  +I  + +  S + +K+  
Sbjct: 2524 EDKEKEKKEGEEEKKT---EKTPEPEAEVEESDYPTINER-LSINNRHRGVSSVVVKDSA 2579

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            R+    Y ++  N  G++S    + V + P  PE P I  +I+  S+ + WK P +D G 
Sbjct: 2580 RADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQI-EDITAHSMLVTWKEP-NDNGS 2637

Query: 1697 ELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754
             +  Y +E+ E +++RW +V  D+  D +   ++ L E   Y+FRV A+N  G  + ++ 
Sbjct: 2638 PIMGYWVERREINSSRWTRVNRDIVPDTQLN-VEGLLEGLTYIFRVAAENQAGPGKFSVP 2696

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW 1813
            S+P   ++ + +P            D+ S+ + W P   NGG  I+ Y V+    G K W
Sbjct: 2697 SDPKTAQSPV-LPPGPPVARVAATTDH-SIDVEWDPPVDNGGGEILGYHVDKAMAGTKDW 2754

Query: 1814 KXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
                          +  +     YQ R+ A N  G   P
Sbjct: 2755 SRSTERPWKNRAFTVYGVREGAKYQIRVIACNAAGEGTP 2793



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 2/167 (1%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++ GS + +       P P  +W   ++ +   +         S +L IK V   D+G Y
Sbjct: 6459 VRAGSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYY 6518

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             L  EN+ G A+  + VT++D P PP  P  I E D  +  + W+ P+  G S I  Y++
Sbjct: 6519 SLSAENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYII 6578

Query: 1418 EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            E  +I   +W++V  + TKT   +  L     Y FR  A N   IS+
Sbjct: 6579 EKCDISQGDWVTVSSSCTKTSFRMTKLIPGKEYGFRVRAENRFGISE 6625



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 93/425 (21%), Positives = 184/425 (43%), Gaps = 32/425 (7%)

Query: 1126 FEIELTKGDALVRWFK---DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            + +E+ K D    W K   D    Q +  ++   +G   + +++  ++   GE S EV  
Sbjct: 5421 YSVEMKKADT-EEWKKVNLDDFIKQCAYRVKGLEEGVTYRFRVFATNMVGDGE-SREVPE 5478

Query: 1183 SKCTA-ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
            S     IL   E  ++ T R    + V  N +    ++   E  +V W K+++V+E++++
Sbjct: 5479 SVVAQDILIPPEIEMDATCRERVTVRVGHNVNIIGYIKARPEP-EVIWSKEETVLENSKR 5537

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRI 1299
             T+I ++    L I++ T  D  +Y     +   +++  + V V++ P    +    Y  
Sbjct: 5538 ITIIQNLPVVHLRIKEATRADHGKYILKASNEGGEASCTITVNVLDRPSHCQNLHTTYAT 5597

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKSASLTIK-KVENTD 1354
            K     + +++++A P+ N    + + I+ +C+         I S   +  IK K+    
Sbjct: 5598 KD----SCMINWEA-PKDNGGSEITNYIV-ECREPSVRMWSMISSNCTNRKIKAKLMEGH 5651

Query: 1355 AGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEIDSSSINICWDEPENTG 1408
              ++++  EN  G    VE    +     L+KP  P    + +I  + + + W +P+  G
Sbjct: 5652 EYLFRVCAENKMGPGPCVETKTPLLAIDPLEKPGEPENFRVTDIGKNHVYLRWRKPDYDG 5711

Query: 1409 NSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             S  + Y +E +  D  EW  ++   +T T         N +Y FR   VNE      S 
Sbjct: 5712 GSPNLSYNLECKAKDAEEWEKLNTGVLTDTFFLADKCIENQTYTFRVQTVNE---GGEST 5768

Query: 1467 TTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
              +   ++ + +IQ P ++  L   +T +  E + +     G PQP+V W +D       
Sbjct: 5769 WVKLSDILVKEEIQKPVIDLKLAGTLTVKVGESVRMEAALRGKPQPEVKWIKDKAVGDNP 5828

Query: 1526 KATYE 1530
            + +YE
Sbjct: 5829 RISYE 5833



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 68/256 (26%), Positives = 117/256 (45%), Gaps = 22/256 (8%)

Query: 1226 DVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            +V W K K+V ++    +    D  K  L   + T+  +   T   L    T    V V+
Sbjct: 5815 EVKWIKDKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIITATNLAGTFTAYANVSVL 5874

Query: 1285 EFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            + P  +    R  R+   G+D   +V + A P+ +    V+S I++KC+  +    + SA
Sbjct: 5875 DVPGPV----RNLRLTGIGADKCRVV-WDA-PEDDGGCEVDSYILEKCETRRMVWSTYSA 5928

Query: 1344 SLT------IKKVENTDAGIYKLRLENNCGH--ADVEMNVTI---LDKPSPPGKPNILEI 1392
            S+       I+ VE  +  I+++R EN  G   A     VT+    +KP PP  P + ++
Sbjct: 5929 SVVTPYCNVIRLVEGNEY-IFRVRAENKMGTGPATETKPVTVKTQFNKPGPPDPPEVTKV 5987

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450
                + + W  PEN G  +I  Y++E +E     W+      I++ +  + NL  N  Y+
Sbjct: 5988 SKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNKSPISERRMKVSNLIPNHEYQ 6047

Query: 1451 FRAYAVNEVDISDASE 1466
            FR  A NEV + + S+
Sbjct: 6048 FRVKAENEVGLGEPSK 6063



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 39/118 (33%), Positives = 65/118 (55%), Gaps = 3/118 (2%)

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            +S+ +K     D G+Y +++EN+ G A     V +L+ P  P KP I +I + S+ + W 
Sbjct: 2571 SSVVVKDSARADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWK 2630

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
            EP + G S I+ Y VE +EI+++ W  V    +  TQ +++ L    +Y FR  A N+
Sbjct: 2631 EPNDNG-SPIMGYWVERREINSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQ 2687



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 8/193 (4%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            L PP  P    + + T+ S+ + W EP  N GSPI  Y +E + +    WT++       
Sbjct: 2606 LEPPEAPEKPQIEDITAHSMLVTWKEPNDN-GSPIMGYWVERREINSSRWTRVNRDIVPD 2664

Query: 1923 HEHCIENIKEKDEIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
             +  +E + E    IFR++AEN  G    S+P++ ++   +     P PP A   +    
Sbjct: 2665 TQLNVEGLLEGLTYIFRVAAENQAGPGKFSVPSDPKTA--QSPVLPPGPPVA--RVAATT 2720

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
             + +   W  P  +GG  +LGY++         W    +       F +  + E   Y I
Sbjct: 2721 DHSIDVEWDPPVDNGGGEILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQI 2780

Query: 2040 RIYARNEIGLSEP 2052
            R+ A N  G   P
Sbjct: 2781 RVIACNAAGEGTP 2793



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 4/171 (2%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +  G  + ++      P P   W  +   + K    K      S SL IK  +    GIY
Sbjct: 4118 VHAGGTIRIIAYVSGKPAPQISWCRDDGEVPK--EAKVETTGISNSLVIKNCKRQHQGIY 4175

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVV 1417
             L  +N  G     + V +LD P P G P   E + + S  + W  PE+ G S I  Y++
Sbjct: 4176 TLSAKNEGGERRKAVIVEVLDVPGPVGLPFAGENLTNDSCKLTWYSPEDNGGSAITNYII 4235

Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
            E +E D   W SV   +T+    +Q L     Y FR  A N + +    ET
Sbjct: 4236 EKRESDRMGWTSVSYTVTRNNAVVQGLLDGKGYFFRIAAENIIGMGPFIET 4286



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 49/175 (28%), Positives = 78/175 (44%), Gaps = 15/175 (8%)

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
            T + + L W +PE +GGS +T +I+E +  K  +W + V    S  E C+  I E  E +
Sbjct: 2947 TRKMIFLNWDDPEDDGGSDLTGFIVERRDAKMHTWRQPVETASSKCE-CV-GIMEGQEYM 3004

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
            FR+ A+N  G+  P E   ++    A  P   T          N +  +W  P  DGG+P
Sbjct: 3005 FRVIAKNKYGMGPPVELGPIK----AVDPQERT---------KNSITLAWKPPRNDGGSP 3051

Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            ++GY +  +   +  +          +   +  L +   Y  RI   N IG SEP
Sbjct: 3052 VIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEP 3106



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 52/214 (24%), Positives = 86/214 (40%), Gaps = 7/214 (3%)

Query: 1287 PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            PP++   ++ +    +K G +V L  +    P P   W  +   +   +  K        
Sbjct: 6825 PPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVH 6884

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             L +  V   + G Y +  EN  G     + V +LDKP PP      ++ S  + + W+ 
Sbjct: 6885 LLELYSVTRKETGDYTILAENINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEP 6944

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITK--TQTSIQNLKTNSSYRFRAYAVNEVD 1460
            P   G S I  Y++E +E     W  V  NI    T  S++ L     Y+FR  A N+  
Sbjct: 6945 PLADGGSEITNYIIEKRETSRANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYG 7004

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
            + D +  T+   V     +  P     + NIT +
Sbjct: 7005 VGDPA-MTDPVTVKNPYDVPGPCEPPVITNITKD 7037



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 2/180 (1%)

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            + + V    +P P  +W    K +    +  + +  S    L +      D G Y L+LE
Sbjct: 1137 LVIRVPITGYPTPVSKWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLE 1196

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
            N+      E+ V ++  PS P    +LE+    +++ W+ P++ G S +  Y VE +++ 
Sbjct: 1197 NDVKSVSGEIEVNVIAAPSAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVS 1256

Query: 1424 TTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
               W+  V  I   + ++ ++     Y F+  A N+    + +   E   +     I  P
Sbjct: 1257 RKTWVKVVTGIQDQEFTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPDP 1316



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 5/146 (3%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            PSPP + ++       + + W  P   G   I  Y +E  E  T +W+ V +  + + + 
Sbjct: 2037 PSPPVELHVTGASRDFLAVAWKPPLRDGGCPISGYHIEMCEAGTEKWMRVNSRPVKELKY 2096

Query: 1439 SIQN-LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
             ++  +     Y  R  A+N V +S+ S+ +E   V  +    +P ++    ++     E
Sbjct: 2097 RVEEGVVPEKEYILRVRAINSVGVSEPSDISE--NVFAKESDCNPALDFQTLDLVVVETE 2154

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK 1523
             + +   F  VP PKVTW++DGK+LK
Sbjct: 2155 KLHIPVPFRAVPSPKVTWHKDGKELK 2180



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 1/119 (0%)

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            S  L +    + DAG YK+ LEN  G A   ++V ++  P P       EI   S  + W
Sbjct: 2206 SCHLEVDSSLHADAGQYKVTLENKLGAASGTISVKVIGLPGPCKDILASEITKHSCKVSW 2265

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
            D P+  G S +I+YV++ +E     +++ +    K   ++++L     Y FR  AVN++
Sbjct: 2266 DPPDYDGGSPVIHYVLQRREAGRRTYVNMMSGENKVSWTVKDLIPGGEYYFRVQAVNKI 2324



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 48/191 (25%), Positives = 77/191 (40%), Gaps = 5/191 (2%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTY 1835
            I   S+ +TW     NG SPI+ Y VE ++    +W           +  ++ L    TY
Sbjct: 2620 ITAHSMLVTWKEPNDNG-SPIMGYWVERREINSSRWTRVNRDIVPDTQLNVEGLLEGLTY 2678

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             FR+ A N+ G        D  T    + PP  P   V + +T  S+ ++W  P  NGG 
Sbjct: 2679 IFRVAAENQAGPGKFSVPSDPKTAQSPVLPPGPPVARVAA-TTDHSIDVEWDPPVDNGGG 2737

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             I  Y ++      K W++            +  ++E  +   R+ A N  G   P  ++
Sbjct: 2738 EILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQIRVIACNAAGEGTPGFTE 2797

Query: 1956 SVRLEKHATVP 1966
            SV +   A  P
Sbjct: 2798 SVFVRNPAGQP 2808



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 38/96 (39%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
            L+   T PS P AP EI     + V  SW  PE DGG+P+ GY I I+D  K+ W+ V  
Sbjct: 3274 LDNGGTPPSMPAAP-EIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVND 3332

Query: 2019 VDV--NTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             D    T +F +  L E   +  RI A N++G S+P
Sbjct: 3333 PDTLHPTTEFTVPSLRELKRHRFRIIAVNDVGESDP 3368



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 6/115 (5%)

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
            TPPS P    +++ T  SVTL W  PE +GGSPI  YII+ +      W + V    ++H
Sbjct: 3279 TPPSMPAAPEIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVR-VNDPDTLH 3337

Query: 1924 ---EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
               E  + +++E     FRI A N VG S P+      L +   +  PP+  +++
Sbjct: 3338 PTTEFTVPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVE--DIQLPPSISIDV 3390



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 9/220 (4%)

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            NDHG    +C V + + P    + E  + +       LVT          ++ Y    + 
Sbjct: 2592 NDHGSASAACEVNVLEPPE---APEKPQIEDITAHSMLVTWKEPNDNGSPIMGYWVERRE 2648

Query: 1614 ENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKP 1669
             N   +    ++    + + ++ L    +  + + A N AG    SV    K    P  P
Sbjct: 2649 INSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQAGPGKFSVPSDPKTAQSPVLP 2708

Query: 1670 EGPVIMREISR--ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
             GP + R  +    S+ +EW PP+D+GG E+  Y ++K       W +  +       + 
Sbjct: 2709 PGPPVARVAATTDHSIDVEWDPPVDNGGGEILGYHVDKAMAGTKDWSRSTERPWKNRAFT 2768

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
            +  + E  +Y  RVIA N  G      +E + ++     P
Sbjct: 2769 VYGVREGAKYQIRVIACNAAGEGTPGFTESVFVRNPAGQP 2808



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 9/136 (6%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I+N + KD   + ISA N  G    T+  S R+E    VP P T  L+  +V   ++  +
Sbjct: 2901 IKNAQRKDCGKYHISACNPSG----TKGASTRVEV-VDVPGPVT-DLKPVVVTRKMIFLN 2954

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  PE DGG+ L G+ +  RD     W +   V+  + K     + E   YM R+ A+N+
Sbjct: 2955 WDDPEDDGGSDLTGFIVERRDAKMHTWRQ--PVETASSKCECVGIMEGQEYMFRVIAKNK 3012

Query: 2047 IGLSEPLESDEPFKVI 2062
             G+  P+E   P K +
Sbjct: 3013 YGMGPPVELG-PIKAV 3027



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 7/160 (4%)

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQV-I 738
            V +  D  +      ++ +K+     + V AVN+ G+       K      E EPP + +
Sbjct: 4346 VRVGGDTKLMDRKFTLSGLKEGSSHEFRVSAVNQVGQGKPSFATKPVQCKDELEPPTLEL 4405

Query: 739  EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPK 795
            +    M+V+ G+S  LS +  G P P I+W KNN+ +K    +   S     S+TI K +
Sbjct: 4406 DIRDKMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHLSLTIAKAR 4465

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
            +    G Y +  EN+ G    +  ITV +  +    P +F
Sbjct: 4466 R-DHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVF 4504



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 16/190 (8%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQ 1836
            +  + +++ W   E +GGS +  + VE +++ K   W+              +     Y 
Sbjct: 2946 VTRKMIFLNWDDPEDDGGSDLTGFIVE-RRDAKMHTWRQPVETASSKCECVGIMEGQEYM 3004

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR+ A+N+ G   P      + +G       Q R       T  S+TL W  P ++GGSP
Sbjct: 3005 FRVIAKNKYGMGPP------VELGPIKAVDPQER-------TKNSITLAWKPPRNDGGSP 3051

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            +  Y +E K    +++    T         +E + +     FRI   N +G S P+   +
Sbjct: 3052 VIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEPSIPLT 3111

Query: 1957 VRLEKHATVP 1966
            V ++     P
Sbjct: 3112 VVIQDDEVAP 3121



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 3/139 (2%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            P PP         SS+  + W  P   G   I+ Y++E Q+    +W    +  +     
Sbjct: 2345 PDPPVDVETHNPTSSTTTLTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPVLSY 2404

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497
            +++ LK   SY FR  A N   +S+ S  T + K +         +   L++ +  +   
Sbjct: 2405 TVRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGY 2464

Query: 1498 DIELTCIFGGVPQPKVTWY 1516
            +I L     G P P++TWY
Sbjct: 2465 EICLDANISGSPYPQITWY 2483



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 87/404 (21%), Positives = 142/404 (35%), Gaps = 39/404 (9%)

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVT------LLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            V+ FP +I   E +  +K G  +       L       P P+  W +N     K +    
Sbjct: 2832 VLVFPTEIPFVELDLSVKNGVTIRAGEILRLPATVTGKPYPSITWTINDAKPDKDRVEIL 2891

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
            S  S S  + IK  +  D G Y +   N  G       V ++D P P      + +    
Sbjct: 2892 SEGSNSI-VEIKNAQRKDCGKYHISACNPSGTKGASTRVEVVDVPGPVTDLKPVVVTRKM 2950

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            I + WD+PE+ G S +  ++VE ++     W        ++     +     Y FR  A 
Sbjct: 2951 IFLNWDDPEDDGGSDLTGFIVERRDAKMHTWRQPVETASSKCECVGIMEGQEYMFRVIAK 3010

Query: 1457 NEVDISDASETTEYYKV--IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            N+  +    E      V   + TK       KP +N    P        + G   + K  
Sbjct: 3011 NKYGMGPPVELGPIKAVDPQERTKNSITLAWKPPRNDGGSP--------VIGYFVEKK-- 3060

Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--CVVGIQQKPV 1572
              +D +  +                        ++    N  GE E S    V IQ   V
Sbjct: 3061 -RQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEPSIPLTVVIQDDEV 3119

Query: 1573 ITISNEDIKQKHKVGDEWLV--------TAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
               + E    KH  GD  +V         A + G+P P++ W K+   +E   E  +   
Sbjct: 3120 ---APEIHMLKHFKGDSIVVKKGDAIEIPADVLGLPIPKIEWSKDDVIIEKPTENLLMET 3176

Query: 1625 EK------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            E       T+ + I  + R     YT+ ASN  G++   +++ V
Sbjct: 3177 EVTGRMNCTTKLSIPSVNRRDRGSYTVSASNNMGSAKHTISVMV 3220



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 68/318 (21%), Positives = 133/318 (41%), Gaps = 29/318 (9%)

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSK-CTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
            +GKK K ++       A   S  VG ++    +  ++E  +   + +P+ + V A +   
Sbjct: 6414 EGKKYKFRV-------AARNSVGVGLAREAEGVFEIKERLMAPKIIMPDIVTVRAGSKMV 6466

Query: 1216 LTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA- 1273
            +   +  +      W +    +  +E+ +++  +   TLII+  T  D   Y+    ++ 
Sbjct: 6467 VEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYYSLSAENST 6526

Query: 1274 -KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
             K+   L+V V++ P      E    I    D+         PQ +    + + II+KC 
Sbjct: 6527 GKANQILRVTVMDIPGPP---EAPLEITE-QDIDACTLLWNSPQEDGGSNITNYIIEKCD 6582

Query: 1333 HTKPSIDSKSASLT------IKKVENTDAGIYKLRLENNCGHADVEMNVTIL-----DKP 1381
             ++    + S+S T       K +   + G +++R EN  G ++   +  I+     D P
Sbjct: 6583 ISQGDWVTVSSSCTKTSFRMTKLIPGKEYG-FRVRAENRFGISEPIYSERIIARYPFDPP 6641

Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTS 1439
            S P    I +I+   + + W+ P + G S I  Y +E +E ++  W+      +  TQ +
Sbjct: 6642 SEPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVKATQYT 6701

Query: 1440 IQNLKTNSSYRFRAYAVN 1457
               L     Y FR  A+N
Sbjct: 6702 CSGLIEGLEYTFRVSALN 6719



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPL--EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005
            V +  +  S        V  PP AP   +I  + ++ ++ +W  P  D G+P++GY +  
Sbjct: 2588 VKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWKEPN-DNGSPIMGYWVER 2646

Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            R++  + W  V +  V   + N+  L E  TY+ R+ A N+ G
Sbjct: 2647 REINSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQAG 2689



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 8/177 (4%)

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375
            P   ++V  + +++          K    T+  +      ++++  EN  G     E+  
Sbjct: 1866 PITNYVVEKRDVRRKGWQAVDTTVKELIYTVTPLNEGSLYVFRVAAENAVGVGPFCELTD 1925

Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
            ++L K     P PP    ++ +    +++ W+ P+N G   I+ Y +E +E   T W+  
Sbjct: 1926 SVLAKDTFTTPGPPYALAVVAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKC 1985

Query: 1431 KNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
               +    +  + ++   +  +F+  A NE  I   SE TE   +   T + SP VE
Sbjct: 1986 GKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVE 2042



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 21/152 (13%)

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP---EGPVIMR--EISRESVT 1684
            +++  L  +H  ++ ++A N       EV L    KPS+P   + P+ ++  + ++ S+T
Sbjct: 6035 MKVSNLIPNHEYQFRVKAEN-------EVGLGEPSKPSRPIAAKDPIGLKVSDSTKTSIT 6087

Query: 1685 IEWKPPLDDGGLELTKYAIE---KHEPDNNR----WIKVADVDRDVET-YCIQKLNENCE 1736
            + W  P+ DGG  +  Y+++   K E D  +    W ++      V T + I +L+E  E
Sbjct: 6088 LSWSKPVYDGGAPIIGYSLDLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKE 6147

Query: 1737 YMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767
            Y F+V AQN VG+   A   E +  K  L+ P
Sbjct: 6148 YEFKVSAQNQVGWGRHAYLKEAVSPKEILEAP 6179



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 11/137 (8%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVL--KIKTGE-KEPPQV---IEPLKSMIVRQ 748
            LK+T + + Q   Y V A+NR G AS P     +I+  + KEPP++    + L  +  + 
Sbjct: 1372 LKVTGLTEGQWYAYRVRALNRLG-ASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKA 1430

Query: 749  GESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G  + L A+V G P P + W K +   KP   +   +     ++TI K K+  D   Y +
Sbjct: 1431 GSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKR-DDSSTYII 1489

Query: 806  KAENSEGIAETSAVITV 822
            +A NS G A  +  + +
Sbjct: 1490 EATNSCGRATATVDVNI 1506



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 39/137 (28%), Positives = 65/137 (47%), Gaps = 8/137 (5%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEK-EPPQVIEPL---KSMIVRQG 749
            K+ N+++     + V+AVN  GE+  P  L+  ++  ++ EPP++I      + +    G
Sbjct: 4758 KVINLEEGALCNFRVMAVNAAGESE-PAYLREAVRVQDRLEPPELILDAGMTREVKAMAG 4816

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
              + L A + G P PT+TW KN   V          T S   ++    +D G YTL  EN
Sbjct: 4817 THITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVEN 4876

Query: 810  SEGI-AETSAVITVEEP 825
              G    T  V+ +++P
Sbjct: 4877 PAGSKTATCTVLVLDKP 4893



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 12/126 (9%)

Query: 716  EGEASLPIVLKIKTGEKEPP-QVIEPLK--SMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            E E S+P+ + I+  E  P   +++  K  S++V++G+++ + A V+G P P I W K++
Sbjct: 3103 ESEPSIPLTVVIQDDEVAPEIHMLKHFKGDSIVVKKGDAIEIPADVLGLPIPKIEWSKDD 3162

Query: 773  ----KPVKAL--PTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAE-TSAVITVE 823
                KP + L   T+  G  +  T L    V  +D G YT+ A N+ G A+ T +V+ + 
Sbjct: 3163 VIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRRDRGSYTVSASNNMGSAKHTISVMVLG 3222

Query: 824  EPTEEN 829
            E    N
Sbjct: 3223 ELKRTN 3228



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 2/82 (2%)

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDE 800
            + ++V  G ++ + A V G P P I+WC+++  V K    ++ G ++S+ ++K  K + +
Sbjct: 4114 EKIVVHAGGTIRIIAYVSGKPAPQISWCRDDGEVPKEAKVETTGISNSL-VIKNCKRQHQ 4172

Query: 801  GVYTLKAENSEGIAETSAVITV 822
            G+YTL A+N  G    + ++ V
Sbjct: 4173 GIYTLSAKNEGGERRKAVIVEV 4194



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 8/109 (7%)

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPT 765
            T + V+   E S PI +     E  PP+V   I     ++V+ GE+V L A+V G P P 
Sbjct: 6803 TAINVSMASELSDPIPV---IAENVPPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPK 6859

Query: 766  ITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812
            +TW ++  P+             + +L+   V  K+ G YT+ AEN  G
Sbjct: 6860 VTWKRDGIPLVLAEGMKMVQKKHVHLLELYSVTRKETGDYTILAENING 6908



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            EN G S I+ Y+VE +E+D   W    +++ KT   + N+     Y FR  A N+  I  
Sbjct: 6272 ENDGGSPILNYIVEKREVDRKTWTKCTEDLKKTSFKVTNMTPGIEYYFRVMACNKYGIGV 6331

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
              ++ + Y  +       P  +  +  IT
Sbjct: 6332 PQDSPKSYLAVDPISEPDPPKKMDVLEIT 6360



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 2/75 (2%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860
            + +KAEN+ G++E S      +  +    P +F++   +  + VK    I L A ++ +P
Sbjct: 2417 FRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGYEICLDANISGSP 2476

Query: 861  VPSITWYRNNEIISP 875
             P ITWY NN++I P
Sbjct: 2477 YPQITWYWNNQVIQP 2491



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 25/86 (29%), Positives = 42/86 (48%)

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
            +E ++ S+T+ WKPP +DGG  +  Y +EK   D   +           T  ++ L++  
Sbjct: 3030 QERTKNSITLAWKPPRNDGGSPVIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAW 3089

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIK 1761
             Y FR+   N +G SE      +VI+
Sbjct: 3090 MYEFRIKCANLIGESEPSIPLTVVIQ 3115



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 3/121 (2%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + + A NS G+        V E  E    P + +     +TV+    + + A V   P P
Sbjct: 6420 FRVAARNSVGVGLAREAEGVFEIKERLMAPKIIMPDI--VTVRAGSKMVVEAIVAGKPAP 6477

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
               W + NE +  SE ++      +  L+I +V +  DSG Y   A NS GK++   RVT
Sbjct: 6478 FCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHV-TRADSGYYSLSAENSTGKANQILRVT 6536

Query: 923  I 923
            +
Sbjct: 6537 V 6537



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 1/121 (0%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + + A N  G  + S      +  +E   P L ++   ++ VK   +  L  R    P P
Sbjct: 4372 FRVSAVNQVGQGKPSFATKPVQCKDELEPPTLELDIRDKMMVKVGDSCTLSGRFGGRPTP 4431

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            +I+W +NNE +   E I  +    ++ L I     +  SG Y     N+AG  S    +T
Sbjct: 4432 AISWTKNNEELKGDEQINLHSTASHLSLTIAKARRD-HSGCYCVNVENTAGSRSGACTIT 4490

Query: 923  I 923
            +
Sbjct: 4491 V 4491



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 7/124 (5%)

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVG 760
            Q  T+ V  VN  GE++   +  I   E+    VI+ LK   ++ V+ GESV + A + G
Sbjct: 5752 QTYTFRVQTVNEGGESTWVKLSDILVKEEIQKPVID-LKLAGTLTVKVGESVRMEAALRG 5810

Query: 761  NPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             P+P + W K +K V   P  S   G  +S  +L   +  D G Y + A N  G     A
Sbjct: 5811 KPQPEVKWIK-DKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIITATNLAGTFTAYA 5869

Query: 819  VITV 822
             ++V
Sbjct: 5870 NVSV 5873



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 4/96 (4%)

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNN-KPVK-ALPTKSDGDTHSITILKPKKVKDEGVY 803
            +R GE + L A V G P P+ITW  N+ KP K  +   S+G ++SI  +K  + KD G Y
Sbjct: 2854 IRAGEILRLPATVTGKPYPSITWTINDAKPDKDRVEILSEG-SNSIVEIKNAQRKDCGKY 2912

Query: 804  TLKAENSEGIAETSA-VITVEEPTEENAEPPLFINR 838
             + A N  G    S  V  V+ P       P+ + R
Sbjct: 2913 HISACNPSGTKGASTRVEVVDVPGPVTDLKPVVVTR 2948



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 9/129 (6%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGTIKLVARVTRNP 860
            + +K  N  G +E S  +TV    +E A     +  F+   I VK+   I++ A V   P
Sbjct: 3093 FRIKCANLIGESEPSIPLTVVIQDDEVAPEIHMLKHFKGDSIVVKKGDAIEIPADVLGLP 3152

Query: 861  VPSITWYRNNEII-SPSETITQNFD--GE---NIELVITNVDSEIDSGDYKCVASNSAGK 914
            +P I W +++ II  P+E +    +  G      +L I +V+   D G Y   ASN+ G 
Sbjct: 3153 IPKIEWSKDDVIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRR-DRGSYTVSASNNMGS 3211

Query: 915  SSHGARVTI 923
            + H   V +
Sbjct: 3212 AKHTISVMV 3220



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 8/138 (5%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI---NRFQEITVKEKGTIKLVARVTRN 859
            + + A N+ G +E  A +      ++  EPP  I      +E+       I L+A +   
Sbjct: 4770 FRVMAVNAAGESEP-AYLREAVRVQDRLEPPELILDAGMTREVKAMAGTHITLMATIKGV 4828

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P++TW +N   + P   I  +     +E+   N +   D GDY     N AG  +   
Sbjct: 4829 PFPTVTWKKNEAEVPPRADIETSQTDSKLEIRFCNRE---DCGDYTLTVENPAGSKTATC 4885

Query: 920  RVTIDVEKVTFVKHLQKS 937
             V + ++K   ++HL+ S
Sbjct: 4886 TVLV-LDKPGPIQHLRVS 4902



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
            P++I P   + VR G  +++ A V G P P   W + N+ V      S   T +   L  
Sbjct: 6449 PKIIMP-DIVTVRAGSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLII 6507

Query: 795  KKVK--DEGVYTLKAENSEGIAETSAVITV 822
            K V   D G Y+L AENS G A     +TV
Sbjct: 6508 KHVTRADSGYYSLSAENSTGKANQILRVTV 6537



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            E DGG+P+L Y +  R+V +  W +  + D+    F + +++    Y  R+ A N+ G+ 
Sbjct: 6272 ENDGGSPILNYIVEKREVDRKTWTKCTE-DLKKTSFKVTNMTPGIEYYFRVMACNKYGIG 6330

Query: 2051 EPLESDEPFKVI 2062
             P +S + +  +
Sbjct: 6331 VPQDSPKSYLAV 6342



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 20/81 (24%), Positives = 44/81 (54%), Gaps = 2/81 (2%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            GS ++   +V+G P P++ W +   ++KP     +     + +T+ I +   +D+ T+  
Sbjct: 1431 GSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGH-STVTIAKTKRDDSSTYII 1489

Query: 584  VAKNAAGFASSTTEL-IVEAP 603
             A N+ G A++T ++ I++ P
Sbjct: 1490 EATNSCGRATATVDVNILDKP 1510



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 9/107 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-- 561
            ++Q+ API +E        +G  V    +V G P P +TW ++ +  KP +   + YD  
Sbjct: 3688 KDQTFAPI-IELRESMEGEEGCDVSMVAKVSGCPFPTLTW-QKASTAKPEEKVAILYDQH 3745

Query: 562  -----DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
                 + +  TL+I++    D+  ++  A N+ G  +   +L V  P
Sbjct: 3746 INKLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSVTKDIKLSVFGP 3792



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 4/81 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ +     ++G P P +TW +  A + P  D +    D   + L IR    ED G +T 
Sbjct: 4816 GTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTD---SKLEIRFCNREDCGDYTL 4872

Query: 584  VAKNAAGFASST-TELIVEAP 603
              +N AG  ++T T L+++ P
Sbjct: 4873 TVENPAGSKTATCTVLVLDKP 4893



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 10/126 (7%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRN 859
            + ++AEN+ G++     + +    +E   PP+    +   + I VK   TI+L A +   
Sbjct: 5063 FRVRAENAIGLSRPDTTLPIL--CQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGI 5120

Query: 860  PVPSITW-YRNNEIISPSETITQNFDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
            PVP+  W     EI S   T     D +N   V++ N  +   SG Y    SN AG  + 
Sbjct: 5121 PVPTAKWSIEGEEITSQGNT---KIDTDNFSTVLSINECTRNHSGTYLLTVSNPAGTKTV 5177

Query: 918  GARVTI 923
               VT+
Sbjct: 5178 ALNVTV 5183



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 16/145 (11%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKE-PPQVIEPLKS---MIVRQGES 751
            + ++++ +   + ++AVN  GE+   P   ++   + + PP +   + +   + +R G+ 
Sbjct: 3344 VPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVEDIQLPPSISIDVTADDLLCIRAGDP 3403

Query: 752  VILSAQVVGNPRPTITW-----CKNNKPVK--ALPTKSD---GDTHSITILKPKKVKDEG 801
            + + A + G P P +TW      K++K  K   LP  S+    DT S+ I+        G
Sbjct: 3404 IRIPATIKGRPAPKVTWDFDGKAKSHKKNKLHTLPVDSEVESTDTTSVVIVPVSLRTHSG 3463

Query: 802  VYTLKAENSEGIAETSA-VITVEEP 825
             YT+ A+N  G    +  VI ++ P
Sbjct: 3464 RYTITAKNKSGQKHVNVRVIVLDVP 3488



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%)

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKV 797
            K++++R G ++ L   V G P P +TW K N  +K     L   S+ DT  + +++    
Sbjct: 7236 KALVLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDT--LLMVEDINR 7293

Query: 798  KDEGVYTLKAENSEGIAETSAVITV 822
             D G Y L  ENS G    + V+ V
Sbjct: 7294 YDAGKYVLMLENSSGSKSYTIVVKV 7318



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 57/268 (21%), Positives = 111/268 (41%), Gaps = 22/268 (8%)

Query: 1482 PTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXX 1534
            P VE  KPL++ T E      L C         V W RDG++++  K  YE      +  
Sbjct: 8    PPVEFTKPLEDQTVEEEATATLECEVSR-ENADVLWLRDGQEIRKTKK-YEMVIDGRKRA 65

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVT 1593
                         Y C A     + +TSC + ++   V  T    D++ + K    +   
Sbjct: 66   LVIHDCTLDDSRTYTCGA----KDFKTSCFLTVEPPHVEFTKPLHDVEVREKESARFECE 121

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
               E I   +V W+K+G+++   K+Y I  + +  V+ + +      ++Y  +A  T+ +
Sbjct: 122  VSRENI---KVRWFKDGSEIRKGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDA-KTSKS 177

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            S +   ++   + +K    V   E  R+SV +  +    D   +++ +  ++  P+  R+
Sbjct: 178  SGMLTVIEEEARFTKNLSHVEAAE--RDSVKLICEVSKPDA--DVSWFKGDEELPEGGRY 233

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRV 1741
              + D  R +      K+ +  EY  R+
Sbjct: 234  EHIVDGKRRILLIRDLKMADAGEYNCRL 261



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 12/162 (7%)

Query: 697  ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI--EPLKSMI-VRQGES 751
            +  +K+ +  T+ V A N  G  E S            +PP+V     L+S + V++G  
Sbjct: 2406 VRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGYE 2465

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD---THSITILKPKKVKDEGVYTLKAE 808
            + L A + G+P P ITW  NN+ ++  P +   +      + I + +K K+     +K +
Sbjct: 2466 ICLDANISGSPYPQITWYWNNQVIQPEPLRKRPERPLKKKVEIKEEEKTKEVTEEEMKED 2525

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
              +   E       E+ TE+  EP   +      T+ E+ +I
Sbjct: 2526 KEKEKKEGEE----EKKTEKTPEPEAEVEESDYPTINERLSI 2563



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 39/175 (22%), Positives = 70/175 (40%), Gaps = 16/175 (9%)

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            ++++ EN  G  +       +    P G   + +   +SI + W +P   G + II Y +
Sbjct: 6048 FRVKAENEVGLGEPSKPSRPIAAKDPIGL-KVSDSTKTSITLSWSKPVYDGGAPIIGYSL 6106

Query: 1418 EYQ---EIDTTE----WISVKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
            + +   E D  +    W  +     +  T+ +I  L     Y F+  A N+V     +  
Sbjct: 6107 DLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKEYEFKVSAQNQVGWGRHAYL 6166

Query: 1468 TEYYKVIKETKIQSPTVEKPL---KNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
             E   V  +  +++P ++      K +       I L  +  G P PKVTW R G
Sbjct: 6167 KE--AVSPKEILEAPEIDLDASLRKGLAVRAGCPIRLFAVIRGRPAPKVTWKRLG 6219



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 21/159 (13%)

Query: 700  VKKFQEG---TYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            V+  QEG    + + AVN  G +     + P+V+K +T       +IE  +SM   +G  
Sbjct: 3654 VEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVIKDQTFAP----IIELRESMEGEEGCD 3709

Query: 752  VILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSI------TILKPKKVK-DEGV 802
            V + A+V G P PT+TW K +  KP + +    D   + +      T+L  +  + D  +
Sbjct: 3710 VSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYDQHINKLVNQDKCTLLIQQACRSDSAI 3769

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
            Y+L A NS G       ++V  P      P  F   F E
Sbjct: 3770 YSLTASNSVGSVTKDIKLSVFGPPGPPVGPVKFTEVFAE 3808



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 23/104 (22%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            + +TV+    + ++  +   P P + W +   ++  S+ IT   +   + L I    +  
Sbjct: 5499 ERVTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEA-TRA 5557

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
            D G Y   ASN  G++S    +T++V ++ +  ++L  +Y T++
Sbjct: 5558 DHGKYILKASNEGGEAS--CTITVNVLDRPSHCQNLHTTYATKD 5599



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 8/118 (6%)

Query: 628  ILEGIPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
            I E +PP             V  G ++ L+  +   P P + W   G  +V  E + +  
Sbjct: 6820 IAENVPPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQ 6879

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
            +  +H+    L++ +V + + G YT++A N  G     I +K+   +  PP  ++  K
Sbjct: 6880 KKHVHL----LELYSVTRKETGDYTILAENINGSKYATIKVKV-LDKPGPPASVKTTK 6932



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +T++    ++L A VT  P PSITW   N+     + +    +G N  + I N   + D 
Sbjct: 2852 VTIRAGEILRLPATVTGKPYPSITW-TINDAKPDKDRVEILSEGSNSIVEIKNAQRK-DC 2909

Query: 902  GDYKCVASNSAGKSSHGARVTI 923
            G Y   A N +G      RV +
Sbjct: 2910 GKYHISACNPSGTKGASTRVEV 2931



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 8/133 (6%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP----LKSMIVRQGESV 752
            +T +++ +   + V A N  G +     L I   EK  P V+E     ++ +IV+ G ++
Sbjct: 5052 VTGLEEGKTYRFRVRAENAIGLSRPDTTLPILCQEKLVPPVVEVDVKLIEGIIVKAGTTI 5111

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809
             L A + G P PT  W    + + +   TK D D  S T+L   +      G Y L   N
Sbjct: 5112 RLPAIMRGIPVPTAKWSIEGEEITSQGNTKIDTDNFS-TVLSINECTRNHSGTYLLTVSN 5170

Query: 810  SEGIAETSAVITV 822
              G    +  +TV
Sbjct: 5171 PAGTKTVALNVTV 5183



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRN 859
            Y ++A N  G ++     T E    +  EPP   L       +T K    I+L A V   
Sbjct: 1385 YRVRALNRLGASQPCKA-TDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGK 1443

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P + W + + ++ P + I+ +    +  + I     + DS  Y   A+NS G+++   
Sbjct: 1444 PEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRD-DSSTYIIEATNSCGRATATV 1502

Query: 920  RVTI 923
             V I
Sbjct: 1503 DVNI 1506



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            ++I V   GTI+++A V+  P P I+W R++  + P E   +   G +  LVI N   + 
Sbjct: 4114 EKIVVHAGGTIRIIAYVSGKPAPQISWCRDDGEV-PKEAKVET-TGISNSLVIKNCKRQ- 4170

Query: 900  DSGDYKCVASNSAGK 914
              G Y   A N  G+
Sbjct: 4171 HQGIYTLSAKNEGGE 4185



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 7/98 (7%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  G+ I L   +  IP P   W  +GEEI    N  +    D   + +VL I    +  
Sbjct: 5105 VKAGTTIRLPAIMRGIPVPTAKWSIEGEEITSQGNTKI----DTDNFSTVLSINECTRNH 5160

Query: 705  EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIE 739
             GTY +   N  G  ++ +   VL +      P  ++E
Sbjct: 5161 SGTYLLTVSNPAGTKTVALNVTVLDVPAAPIGPVDILE 5198



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 5/93 (5%)

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL--FINRFQEITVK 845
            S  ++K     D GVY +K EN  G A  +  + V EP E   +P +         +T K
Sbjct: 2571 SSVVVKDSARADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWK 2630

Query: 846  E---KGTIKLVARVTRNPVPSITWYRNNEIISP 875
            E    G+  +   V R  + S  W R N  I P
Sbjct: 2631 EPNDNGSPIMGYWVERREINSSRWTRVNRDIVP 2663



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 41/195 (21%), Positives = 84/195 (43%), Gaps = 14/195 (7%)

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287
            W K  +++ DT +  + +     TL+IR C   D   YT  + ++  +   K  + V   
Sbjct: 7551 WKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTYTINVRNSAGSKDCKFSLKVVGR 7610

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK---PSIDS--KS 1342
            P I     ++       +TL       P+ +    V++ I++K + T     ++ S  + 
Sbjct: 7611 PGICTGPIQFDEITADGITL---EWGPPKDDGGAEVSNYIVEKRRTTDNKWATVASAIQK 7667

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSI 1397
             S+ + +++     I+++  EN  G  +   +  ++ +     P  P  P I+ I   S 
Sbjct: 7668 TSMRVIRLQEGKEYIFRVFAENKYGVGEYLRSEPVIAQHPFNVPGAPAPPEIVSIRHESA 7727

Query: 1398 NICWDEPENTGNSTI 1412
             + W +P++TG S I
Sbjct: 7728 ILTWADPKDTGGSPI 7742



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 506 QSMAPI-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           +S  P+ F + L  +   + +T   EC+V       + W R    I+ ++ ++M  D   
Sbjct: 5   RSEPPVEFTKPLEDQTVEEEATATLECEVSR-ENADVLWLRDGQEIRKTKKYEMVIDGRK 63

Query: 565 VATLVIREVFPEDAGTFTCVAKN 587
            A LVI +   +D+ T+TC AK+
Sbjct: 64  RA-LVIHDCTLDDSRTYTCGAKD 85



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAII-KPSQDFQMYYDDD---NVAT-LVIREVFPEDA 578
            G  ++    V G P P+I W +   II KP+++  M  +     N  T L I  V   D 
Sbjct: 3139 GDAIEIPADVLGLPIPKIEWSKDDVIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRRDR 3198

Query: 579  GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            G++T  A N  G A  T  ++V   L      +T+
Sbjct: 3199 GSYTVSASNNMGSAKHTISVMVLGELKRTNDCLTI 3233



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 7/108 (6%)

Query: 1357 IYKLRLENNCGHA--DVEMNVTILDKPS-PPGKP--NILEIDSSSINICWDEPENTGNST 1411
            I+++  EN  G     V  +      P  PPG P   +      SI++ WD P + G   
Sbjct: 2679 IFRVAAENQAGPGKFSVPSDPKTAQSPVLPPGPPVARVAATTDHSIDVEWDPPVDNGGGE 2738

Query: 1412 IIYYVVEYQEIDTTEWI-SVKNITKTQT-SIQNLKTNSSYRFRAYAVN 1457
            I+ Y V+     T +W  S +   K +  ++  ++  + Y+ R  A N
Sbjct: 2739 ILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQIRVIACN 2786


>UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - Aedes
            aegypti (Yellowfever mosquito)
          Length = 7100

 Score =  270 bits (663), Expect = 2e-70
 Identities = 201/700 (28%), Positives = 306/700 (43%), Gaps = 40/700 (5%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENT 1353
            R+  ++ G D  + + Y AFP+P   W  N + +  K       +  ++A   +   + T
Sbjct: 4790 RDITVRAGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTRVHQQLTDEAAIFVVTNSKRT 4849

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
            D+  Y+L L+N  G+     N  +LD+PS P    +       + +CW+ P + G S + 
Sbjct: 4850 DSKQYRLMLKNPSGYDIATCNAKVLDRPSKPENIGVESYGGEHLTLCWNAPLDDGGSPVT 4909

Query: 1414 YYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             YVVE +E +++ W  V +  T T   I+NL+ N  Y FR YA N+  +S+ +++     
Sbjct: 4910 NYVVERKEKNSSNWTKVSSYCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDT--- 4966

Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF----GGVPQPKVTWY-------RDGK 1520
            +I +     PT    P +  TTE  + + +T I     GG P   +T Y        +G 
Sbjct: 4967 IIAKHPFDVPTQPGTPTRVETTE--DSVTITWIKPASNGGSP---ITHYIVEKRPAAEGT 5021

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC------VVGIQQKPVIT 1574
              K  + T ++                ++  A N  G+   S       V      P IT
Sbjct: 5022 WTKVQQGTLKD-LMCKVSGLTENREYIFRVAAVNAAGQSPFSAASDPIMVTAAFTAPKIT 5080

Query: 1575 --ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
              I   DI    +  D + +       P P+  W  NGN++  ++   +   +  ++ + 
Sbjct: 5081 SDIGMRDILVIAR--DPFKIIVPFSASPRPDAFWLVNGNEVSRNERIELQVTDTEAIFKN 5138

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
               KR  S  YTI   N  G  S    + V DKP+ P GP+ + EI+ ES T+ WK PLD
Sbjct: 5139 DNAKRLDSGSYTIHLVNCVGKDSASCRVLVVDKPTPPIGPLEVSEITPESCTLSWKVPLD 5198

Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
            DGG  +T Y +E++EP    W K +   R    Y    +  N +Y FRV A+N  G S+ 
Sbjct: 5199 DGGSPITNYIVERYEP-LGYWTKASSFVRSTH-YDNMGMENNKQYSFRVRAENQYGISDP 5256

Query: 1753 L-ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EG 1810
            L   EPI+ +    VP            D   V +TW     +GGS I  Y+ E +    
Sbjct: 5257 LILEEPIIARYPFTVPDPPNPPRVSDW-DASYVTVTWERPLMDGGSRIQGYRFEYRDVTD 5315

Query: 1811 KKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
              W          + ++  L     Y+FR+ A+N  G S P  S  +  I   +TPPS P
Sbjct: 5316 STWIVCNFLIKDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAP 5375

Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
                V +     V L WT P S+GGS IT Y +E + + G  W K       V E  I N
Sbjct: 5376 GAPAVIKVGKSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTELTITN 5435

Query: 1930 IKEKDEIIFRISAENTVGVSLP-TESQSVRLEKHATVPSP 1968
            + E     FR+ A N  GVS P TE++SVR+ +      P
Sbjct: 5436 LIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKP 5475



 Score =  251 bits (615), Expect = 1e-64
 Identities = 335/1348 (24%), Positives = 547/1348 (40%), Gaps = 113/1348 (8%)

Query: 705  EGT---YTVVAVNR--EGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQV 758
            EGT   + V A+NR  EGEAS P    I   + +PP++    L ++ +R G +      V
Sbjct: 3462 EGTAYQFRVKAINRAGEGEASKPTDSHIARSKNQPPKIDRYSLSNVKIRAGLTFEFDVPV 3521

Query: 759  VGNPRPTITWC-KNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAE 815
             G P P   W  K+N  +     K   + +  T L+   VK  D GVYTL A+N  GI  
Sbjct: 3522 QGEPVPAKEWTHKDNMIINTDRVKVVYENYR-TKLRVMDVKRSDSGVYTLTAKNKNGIDI 3580

Query: 816  TSA-VITVEEPTEENAEPPLFINRFQEITV-------KEKGTIKLVARVTRN-PVPSITW 866
                V+ ++ P     E P+      +  V       K+ G  +++  V        + W
Sbjct: 3581 ADVNVVVLDVPAPP--EGPIRHENLSKTGVTLMWRPPKDDGGSEILHYVVEKLDTDQLRW 3638

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDS----GDYKCVASNSAGKSSH-GARV 921
                E IS         +G + +  +  V+ + +S          A +   K    G  V
Sbjct: 3639 IPVGETISTKIRPDNLIEGHSYQFRVRAVNKQGESIPLSTSQPITAKDPYTKPDKPGKPV 3698

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981
             +D     +V  L+ S   ++G + I    TS+ V  K  +   + +G          + 
Sbjct: 3699 VVDWSD-NYVT-LEWSIPKKDGGSPI----TSYVVEKKPRYGDWKFAGEFTELFKPHAKI 3752

Query: 982  XXXXXXXXXXXDV-GVIKCIVKD-QETSTMLVVKETI--PEFIRK-LQDFEVKEKDVAIL 1036
                        +  V K  V D  E+S  +V K     P F +  L+D  V        
Sbjct: 3753 TDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRFVPPHFDKNALKDLIVPVGKKIAY 3812

Query: 1037 EVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094
             V +  S      W+RDG +I P+  +   E   +   L I  +   D G Y+ I+++  
Sbjct: 3813 NVTVEASPNVTATWKRDGVVI-PESQRVIREAYNNEVSLEIPFSIREDCGMYTLIVKNSC 3871

Query: 1095 ---SCTAEVTVVELP--PEIITRLQN------------QKVNKGNKATFEIELTKGDALV 1137
               S +  VTV++ P  PE   R+ N             K + G+  T  +      +  
Sbjct: 3872 GEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKMDMSRG 3931

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
             W   G     +N I   I  K+   ++    +++ GE      +    A    EEPS  
Sbjct: 3932 TWSAAGMSTSLANEISRLIHNKRYSFRVKA--VNEIGESEPLESSHPIVAKNDFEEPS-- 3987

Query: 1198 FTLRLPEFILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVK--KRTL 1253
                 P+ +   AN+ + L    P  D    +T Y  +   +D+  ++    V   +R L
Sbjct: 3988 -QPPKPQVVDWDANSVS-LEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRVPGIQRNL 4045

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK-------LKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
             +     + + E+  + ++A   ++       +        PKIV   R+  +K G    
Sbjct: 4046 KVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGLIFH 4105

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            L V++   P P   W +N K ++  K T  +       +        D+G YKL++ N+ 
Sbjct: 4106 LDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKLKISNSS 4165

Query: 1367 GHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI-DT 1424
            G  +  +++T+LD+P PP G  N  EI   S+ I W  P++ G S I  YVVE +++   
Sbjct: 4166 GTDEGSLHLTVLDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSEITGYVVEKKDLTHG 4225

Query: 1425 TEWI-SVKNITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
              W+ +V  ++   T T +  L   + Y FR  A N    SD       + V+ + +   
Sbjct: 4226 GGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDG--LMSKHPVVAKDQFVV 4283

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQ--PKVTWY----RD---GKKLKTAKATYENR 1532
            P    P K   T+ N D         +     +++ Y    RD   G+ ++  K    N 
Sbjct: 4284 P--GPPTKPDITDSNYDFITLSWKPPISDGGSRISGYNIERRDTATGRWIQANKYPIPN- 4340

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETS-----C-VVGIQQKPVITISNEDIKQ-KHK 1585
                           Y+  A N  G+ + S     C    +QQ P + + +   +  K +
Sbjct: 4341 IEFTDTGVMRGHQYDYRVSAVNAAGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVR 4400

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
             G+  ++T  + G P P V W++NG K+       I T  + +V R++  +R  S  Y I
Sbjct: 4401 AGEPIIITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKI 4460

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            +ASN  G  + E  + V D+P  P   V   E ++++VT+ W PP DDGG E+T Y+IE 
Sbjct: 4461 KASNQYGEDTREFEVIVVDRPQPPRN-VFALETTQDTVTLNWDPPKDDGGSEITGYSIEY 4519

Query: 1706 HEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
             E  ++ W  V   V R   T  I+ L EN EY+FRV A+N  G S+  ES+ I  K+  
Sbjct: 4520 KEFPSDNWKMVYGTVPRCAHT--IKHLTENHEYIFRVRAENIYGASDPTESKTISPKSP- 4576

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXX--XXX 1821
            D P             + S  I+W P       P+  Y VE ++ G  +W          
Sbjct: 4577 DPPQTVDKPAVEDYTPS-SCTISWKPPRVQ-TRPVTGYIVEKRERGTGEWVQVNNYPTVN 4634

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                I  L     Y+FR+ + N++G S P    D IT       P+QP    + + +  +
Sbjct: 4635 TTYTIPDLMEGFRYEFRVKSVNDVGVSKPSEPTDPITAQYQRKRPNQPDPPSIDKISRNN 4694

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG--SVHEHCIENIKEKDEIIFR 1939
            VTL W     +    I  Y+I+++      W    +     S   + +EN++E  E  FR
Sbjct: 4695 VTLSWRTLRRDAKEKIKGYLIQYRIKDEDKWIDSNSAADLCSDQSYRVENLEENKEYQFR 4754

Query: 1940 ISAENTVGVSLPTE-SQSVRLEKHATVP 1966
            + A N +G S P+  S SV L++    P
Sbjct: 4755 LIAVNDIGSSDPSRPSISVILQEQPNKP 4782



 Score =  245 bits (600), Expect = 9e-63
 Identities = 223/804 (27%), Positives = 339/804 (42%), Gaps = 58/804 (7%)

Query: 1287 PPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            PPKI      + RIK G++V   V     P P  +W++N + +K+ +  K      +  +
Sbjct: 3199 PPKIDRTNLIDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKI 3258

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
            TI+     ++G Y +  EN  G     + VT+LD PSPPG P  + EI ++   + W  P
Sbjct: 3259 TIRSATRGESGTYTIEAENENGKDTATVFVTVLDVPSPPGGPLKVPEITANGAILEWRAP 3318

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            E+ G   I  Y++E  +     W+       +K Q  I  L    SY+FR  A N++  S
Sbjct: 3319 EDDGGLPIDNYIIEKLDEAKGTWVYAGDSGSSKCQAEIDGLIEGHSYKFRVRAQNKMGKS 3378

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVP-----QPKV 1513
            +         V+ +   ++P   + L  IT    + +EL        GG P       K+
Sbjct: 3379 EPLSMAN--AVVAKNPFRAPQRPENL-TITDYDKDYVELEWKAPENDGGAPITGYVVEKL 3435

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQ 1569
            + Y  G   K A+   +                 ++  A N  GE E    T   +   +
Sbjct: 3436 SKY-SGDWEKCAEVEGD-ACTAKVPDLIEGTAYQFRVKAINRAGEGEASKPTDSHIARSK 3493

Query: 1570 KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
                 I    +   K + G  +     ++G P P   W    N + N     +  +   +
Sbjct: 3494 NQPPKIDRYSLSNVKIRAGLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYRT 3553

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             +R+ ++KRS S  YT+ A N  G    +V + V D P+ PEGP+    +S+  VT+ W+
Sbjct: 3554 KLRVMDVKRSDSGVYTLTAKNKNGIDIADVNVVVLDVPAPPEGPIRHENLSKTGVTLMWR 3613

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            PP DDGG E+  Y +EK + D  RWI V + +   +       L E   Y FRV A N  
Sbjct: 3614 PPKDDGGSEILHYVVEKLDTDQLRWIPVGETISTKIRP---DNLIEGHSYQFRVRAVNKQ 3670

Query: 1748 GFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
            G S  L  S+PI  K     P            DN  V + W   +K+GGSPI  Y VE 
Sbjct: 3671 GESIPLSTSQPITAKDPYTKPDKPGKPVVVDWSDN-YVTLEWSIPKKDGGSPITSYVVEK 3729

Query: 1807 KQEGKKWKXXXXXXXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
            K     WK            A+I  L  +  Y+FRI A N+ G S P  S D I      
Sbjct: 3730 KPRYGDWKFAGEFTELFKPHAKITDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRF 3789

Query: 1864 TPPSQPRNFV------VSESTSRSVTLKWTEPESNGGSPITNYII-EFKTVKGKSWTKIV 1916
             PP   +N +      V +  + +VT++   P           +I E + V  +++   V
Sbjct: 3790 VPPHFDKNALKDLIVPVGKKIAYNVTVE-ASPNVTATWKRDGVVIPESQRVIREAYNNEV 3848

Query: 1917 T--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            +  +  S+ E C          ++ +  +N+ G    +   +V L+K    PSPP  PL 
Sbjct: 3849 SLEIPFSIREDC---------GMYTLIVKNSCGEYSASGHVTV-LDK----PSPPEGPLR 3894

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
            I  + +      W  P+ DGG+P+  Y I   D+++  W   G     +L   I  L  N
Sbjct: 3895 ITNITTEGCHLEWKLPKDDGGSPITHYVIEKMDMSRGTWSAAGM--STSLANEISRLIHN 3952

Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058
              Y  R+ A NEIG SEPLES  P
Sbjct: 3953 KRYSFRVKAVNEIGESEPLESSHP 3976



 Score =  239 bits (586), Expect = 5e-61
 Identities = 206/781 (26%), Positives = 326/781 (41%), Gaps = 46/781 (5%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
            G  +   V  +A P     W  +  +I + +       +   SL I      D G+Y L 
Sbjct: 3807 GKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLI 3866

Query: 1362 LENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
            ++N+CG      +VT+LDKPSPP  P  I  I +   ++ W  P++ G S I +YV+E  
Sbjct: 3867 VKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKM 3926

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
            ++    W +    T     I  L  N  Y FR  AVNE+  S+  E++  + ++ +   +
Sbjct: 3927 DMSRGTWSAAGMSTSLANEISRLIHNKRYSFRVKAVNEIGESEPLESS--HPIVAKNDFE 3984

Query: 1481 SPTVEKPLKNITTEPNE-DIELTC--IFGGVPQPKVTWYRDGKKLK------TAKATYEN 1531
             P+     + +  + N   +E       GG P   +T Y   KK K      TA      
Sbjct: 3985 EPSQPPKPQVVDWDANSVSLEWNAPKSDGGAP---ITEYIVQKKEKDSPYWSTAGRVPGI 4041

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQ--KPVITISNEDIKQKHK 1585
            +               ++ IA N  GE E S     V+   +   P I     D+  K  
Sbjct: 4042 QRNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVK-- 4099

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
             G  + +     G P PEV+W  NG  +E+DK   +T     +++      R  S  Y +
Sbjct: 4100 AGLIFHLDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKL 4159

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            + SN++GT    + L V D+P  PEGP+   EI+ +SVTI WKPP D+GG E+T Y +EK
Sbjct: 4160 KISNSSGTDEGSLHLTVLDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSEITGYVVEK 4219

Query: 1706 HE-PDNNRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKT 1762
             +      W+  VA V        + +LN+  +Y FRV+A+N  G S+ L S+ P+V K 
Sbjct: 4220 KDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLMSKHPVVAKD 4279

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821
               VP            + + + ++W P   +GGS I  Y +E +     +W        
Sbjct: 4280 QFVVPGPPTKPDITDS-NYDFITLSWKPPISDGGSRISGYNIERRDTATGRWIQANKYPI 4338

Query: 1822 XXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                     +     Y +R+ A N  G   P     K        P  Q     +     
Sbjct: 4339 PNIEFTDTGVMRGHQYDYRVSAVNAAGQGQPSDPSSKC----WAKPMQQAPKLNLDSFGK 4394

Query: 1880 RSVTLKWTEP----ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKD 1934
            R++ ++  EP        G+PI         VK    ++      S H    +E  + KD
Sbjct: 4395 RTIKVRAGEPIIITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKD 4454

Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG 1994
               ++I A N  G     E + + +++    P PP     +      + + +W  P+ DG
Sbjct: 4455 SDTYKIKASNQYGED-TREFEVIVVDR----PQPPRNVFALETTQDTVTL-NWDPPKDDG 4508

Query: 1995 GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            G+ + GY+I  ++     W  V    V      I+ L+ENH Y+ R+ A N  G S+P E
Sbjct: 4509 GSEITGYSIEYKEFPSDNWKMVYGT-VPRCAHTIKHLTENHEYIFRVRAENIYGASDPTE 4567

Query: 2055 S 2055
            S
Sbjct: 4568 S 4568



 Score =  237 bits (580), Expect = 2e-60
 Identities = 203/790 (25%), Positives = 320/790 (40%), Gaps = 35/790 (4%)

Query: 1286 FPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342
            F P  +D    +   +K G  + L       P P   W++N +++ K     +   +   
Sbjct: 2311 FAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYR 2370

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
            A LTI  V     G Y+++ EN+ G+ + +  +T+LDKP+ P  P  +  +     ++ W
Sbjct: 2371 AKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITVLDKPTAPEGPLKVSNVHKEGCSLKW 2430

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
            + P + G   I +Y VE  + +T  W+ V     T   + NL+    Y FR  AVN+  +
Sbjct: 2431 NPPLDDGGVPIDHYNVEKFDKETGRWVPVGRTPDTHMDVTNLEPGQEYLFRVSAVNDEGV 2490

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT----CIFGGVPQPK-VTWY 1516
            S+   T ++  ++ +     P      +    + N  IEL        GG P  K +   
Sbjct: 2491 SEPLSTEQF--IMAKNPFDEPGKPGTPEAYDWDRNF-IELRWTPPVCDGGSPITKYIVEK 2547

Query: 1517 RDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKP-- 1571
            R+   +K  +A     N+               +K  A N+ G  V +     I  KP  
Sbjct: 2548 REHGTIKWIRAAEVIGNKCEAKVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPRK 2607

Query: 1572 -VITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
                I   ++K     +G+ +     I G P P+V W  N   +       I      S 
Sbjct: 2608 LPPKIDRRNLKNLSVAIGEPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYNSK 2667

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689
                   R  S KY I+A+N  GT  VE+T+ V  KPS PEGP+ +++++++S  +EW+ 
Sbjct: 2668 FANTNPDRRDSGKYVIKATNKFGTDQVEITVTVRSKPSAPEGPLEVKDMTKDSCRLEWQK 2727

Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
            P DDGG+ +  Y +EK +PDN  W+    V+     + ++ L     Y FRV A N  G 
Sbjct: 2728 PKDDGGVPIDHYVVEKFDPDNGIWMTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGE 2787

Query: 1750 SEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
            S+ LES    + K +  VP            +N +V + W P   +GGSPI  Y +E K 
Sbjct: 2788 SDPLESAGTYLAKDSFSVPDTPSAPTVVDWSENHAV-LKW-PEPDDGGSPITGYIIEKKD 2845

Query: 1809 E-GKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            +    W+           A +  L     YQFR+ A N+ G S P  +    T      P
Sbjct: 2846 KYSPIWEKACETTSPSPTATVGGLVEGNEYQFRVIAVNKAGQSDPSDASRTFTAKPRFAP 2905

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P   R  +   S S    LK+    S   +P   + +   TV      +I+    +  + 
Sbjct: 2906 PKIDRRTIRDISISAGSMLKFDVNVSGEPAPKCEWRVNKATVSSDRRLEILNTDYN-SKF 2964

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
             +      D   + I+A N+ G        +V        P  P  PL++  V       
Sbjct: 2965 ILRPANRNDSGDYEITATNSSGRDYVCVQVTV-----TDKPGAPEGPLQVSDVTKETCKL 3019

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWM-EVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
             W  P  DGG  +  Y I   D     W+     V+ N    +I  L     Y  R+ A 
Sbjct: 3020 KWKRPRDDGGCDIEYYQIERFDEDANAWVPHARSVETNA---DISGLQNGKKYKFRVSAV 3076

Query: 2045 NEIGLSEPLE 2054
            N  G S+PLE
Sbjct: 3077 NAEGESKPLE 3086



 Score =  235 bits (576), Expect = 7e-60
 Identities = 204/778 (26%), Positives = 332/778 (42%), Gaps = 32/778 (4%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
            IK G  V   +D +  P P  +W    K ++    +   ++D  +    ++   N  +G 
Sbjct: 1734 IKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNL-SGK 1792

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYV 1416
            Y +   N+ G    E+ +TIL KP  P  P    E+      + W  P + G   I  Y 
Sbjct: 1793 YTIVATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKPPLDDGGMPIDGYE 1852

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +E  +  T +WI     +  + +I  L+    Y+FR  A N+   S+  E  E   + K+
Sbjct: 1853 IEKLDPLTGQWIPCGQSSTPEANISGLQEGKQYKFRVKAFNKEGDSEPLEM-ETIVIAKD 1911

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPK-VTWYRD--GKKLKTAKATYEN 1531
               +     +P      +   D+E T     GG P  + +   RD   +K + A     +
Sbjct: 1912 PFSEPSKPGRPTPTDWGKDFVDLEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGD 1971

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKP---VITISNEDIKQKH-KV 1586
            R               ++ IA N  G  E S +   +  KP      I  +++ +K  + 
Sbjct: 1972 RTRGTVEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRF 2031

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            G    V A + G P P++ W   G  +  + D+   +  ++  + + I+ LKRS S  Y 
Sbjct: 2032 GQLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYK 2091

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            + A N  GT +VE+ L V  KPSK  GP+ + +++ E   + W PP DDGG  +  Y +E
Sbjct: 2092 VTAKNKNGTDTVEMELVVLAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQAYVVE 2151

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTA 1763
            + + D+ RWI+V +  R  E   +  L E  +YMFRV A N  G SE LE+E     K  
Sbjct: 2152 RMDVDSGRWIQVCET-RFPEAD-VSGLQEGKDYMFRVKAVNSEGESEPLETETSTRAKNP 2209

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXX- 1821
             D PS             + V + W   E +GG+PI  Y +E K     KW         
Sbjct: 2210 YDAPSAPGKPKATDW-SRKHVMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAMETDGP 2268

Query: 1822 -XXARIQKLSINTTYQFRIYARNEIGTSLPYTS-DDKITIGKTLTPPSQPRNFVVSESTS 1879
               A++Q L   TTYQFR+ A N+ G S PY+   D + +     PP   R+ + + +  
Sbjct: 2269 VNKAKVQDLFEGTTYQFRVKAVNKGGPS-PYSPLSDPVLVKDRFAPPRIDRSTLKNMTLK 2327

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
               +L+     S   +P   +++    V+  +    V       +  I  +       + 
Sbjct: 2328 GGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTYE 2387

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            I AEN+ G      + +V L+K    P+ P  PL++  V        W  P  DGG P+ 
Sbjct: 2388 IKAENSSGYDEHQFTITV-LDK----PTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVPID 2442

Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             YN+   D     W+ VG+        ++ +L     Y+ R+ A N+ G+SEPL +++
Sbjct: 2443 HYNVEKFDKETGRWVPVGRTP--DTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQ 2498



 Score =  229 bits (561), Expect = 5e-58
 Identities = 237/932 (25%), Positives = 393/932 (42%), Gaps = 79/932 (8%)

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYK 1231
            AG+      +SKC A    + P +N        I V A     +T+ +    +  V W++
Sbjct: 4364 AGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVRAGEPIIITIPLVGAPIPTVEWFR 4423

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP-- 1287
                I +T + T+ ++ +     + +    D   Y     +   + T + +V VV+ P  
Sbjct: 4424 NGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKIKASNQYGEDTREFEVIVVDRPQP 4483

Query: 1288 PKIV---DYEREY--------RIKRGSDVT-LLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            P+ V   +  ++         +   GS++T   ++Y+ FP  +D W +    + +C HT 
Sbjct: 4484 PRNVFALETTQDTVTLNWDPPKDDGGSEITGYSIEYKEFP--SDNWKMVYGTVPRCAHT- 4540

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPP---GKPNILE 1391
                       IK +      I+++R EN  G +D   + TI  K P PP    KP + +
Sbjct: 4541 -----------IKHLTENHEYIFRVRAENIYGASDPTESKTISPKSPDPPQTVDKPAVED 4589

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSY 1449
               SS  I W +P       +  Y+VE +E  T EW+ V N     T+  I +L     Y
Sbjct: 4590 YTPSSCTISW-KPPRVQTRPVTGYIVEKRERGTGEWVQVNNYPTVNTTYTIPDLMEGFRY 4648

Query: 1450 RFRAYAVNEVDISDASETTE----YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-- 1503
             FR  +VN+V +S  SE T+     Y+  +  +   P+++K  +N  T     +      
Sbjct: 4649 EFRVKSVNDVGVSKPSEPTDPITAQYQRKRPNQPDPPSIDKISRNNVTLSWRTLRRDAKE 4708

Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE 1560
             I G + Q ++   +D  K   + +  +                 Y  + IA ND G  +
Sbjct: 4709 KIKGYLIQYRI---KDEDKWIDSNSAADLCSDQSYRVENLEENKEYQFRLIAVNDIGSSD 4765

Query: 1561 TS----CVVGIQQ--KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
             S     V+  +Q  KP++ + N  DI  +   G+++ +       P P   W+ N  +L
Sbjct: 4766 PSRPSISVILQEQPNKPMMDLRNVRDITVR--AGEDFNIHIPYTAFPKPVATWFANDEQL 4823

Query: 1614 EN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            ++ D   +    ++ ++  +   KR+ S +Y +   N +G        KV D+PSKPE  
Sbjct: 4824 DDKDTRVHQQLTDEAAIFVVTNSKRTDSKQYRLMLKNPSGYDIATCNAKVLDRPSKPEN- 4882

Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKL 1731
            + +     E +T+ W  PLDDGG  +T Y +E+ E +++ W KV+       TY  I+ L
Sbjct: 4883 IGVESYGGEHLTLCWNAPLDDGGSPVTNYVVERKEKNSSNWTKVSSY--CTTTYLKIRNL 4940

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
              N +Y FRV A+N  G SE  +S+ I+ K   DVP+           + +SV ITW   
Sbjct: 4941 RINQQYEFRVYAENKYGMSEPAQSDTIIAKHPFDVPTQPGTPTRVETTE-DSVTITWIKP 4999

Query: 1792 EKNGGSPIIDYKVEIK--QEGKKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
              NGGSPI  Y VE +   EG   K           ++  L+ N  Y FR+ A N  G S
Sbjct: 5000 ASNGGSPITHYIVEKRPAAEGTWTKVQQGTLKDLMCKVSGLTENREYIFRVAAVNAAGQS 5059

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSE-STSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
                + D I +    T P    +  + +         K   P S    P   +++    V
Sbjct: 5060 PFSAASDPIMVTAAFTAPKITSDIGMRDILVIARDPFKIIVPFSASPRPDAFWLVNGNEV 5119

Query: 1908 KGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
                  ++ VT   ++ ++  +N K  D   + I   N VG     +S S R+      P
Sbjct: 5120 SRNERIELQVTDTEAIFKN--DNAKRLDSGSYTIHLVNCVG----KDSASCRV-LVVDKP 5172

Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
            +PP  PLE+  +       SW  P  DGG+P+  Y I  R      W +     V +  +
Sbjct: 5173 TPPIGPLEVSEITPESCTLSWKVPLDDGGSPITNY-IVERYEPLGYWTKASSF-VRSTHY 5230

Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
            +   +  N  Y  R+ A N+ G+S+PL  +EP
Sbjct: 5231 DNMGMENNKQYSFRVRAENQYGISDPLILEEP 5262



 Score =  229 bits (560), Expect = 6e-58
 Identities = 296/1272 (23%), Positives = 483/1272 (37%), Gaps = 75/1272 (5%)

Query: 841  EITVKEKGTIKLVARVT-RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            +IT KE    K++       P     W    + I          +G+    +I N   E 
Sbjct: 170  DITCKEGREKKVIFECAFTKPNAKAKWMLRKDEIFTGPKYKFKTEGDVYSCLIINPKVE- 228

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVILECQTSHTVST 958
            DSG Y       AG S        + + V  F K L+K+ +        LEC   ++++ 
Sbjct: 229  DSGKYTI---EIAGISCFAYLTVEEADPVYKFTKTLKKNEKGFITHDTHLECAVDNSLAP 285

Query: 959  -KWYHNKKEISGMDHREIIQE--GRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVK 1013
              W+  + ++     + +I +                D     C ++ Q  +T T L + 
Sbjct: 286  ISWWKGETKLENDGEKYVIGKDLNGTVTLIIKNSVLEDADTYTCKIEKQTDKTETKLKIL 345

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            E   +F + L+  ++  KD   L  E++     V W +  E I  + +K    K G   K
Sbjct: 346  EYNYKFTKVLKSQQLFVKDTVTLACELDHVLGTVEWFKGDEKIV-ESDKVQIIKDGRKHK 404

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133
            L +++ +  D G Y C+   +   AE+  V+ P + + +L++   ++  +   +I++   
Sbjct: 405  LVLKDVAKADSGMYRCVSNADKTEAEI-FVKRPNKFMKKLKDTTGDETKECVLDIQVQDE 463

Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVG--NSKCTAILT 1190
            +A V++F   +EI  ++ I +   G    KL     +L DAGE +C  G   SKCT  + 
Sbjct: 464  EADVQFFLGETEIVKNDRIDIVSPGDGTWKLVYKKLELGDAGEITCVCGPLTSKCTLKVN 523

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTV-----EIPDETLDVTWYKKKSVIEDTEKFTLI 1245
             +E    F   +P  +  PA  +  L V     E     +    +K    +   E   ++
Sbjct: 524  KKETKPKF--EVPPKVETPAKVEKVLEVPFTTGESRQSKVTAKVFKVGKPVTPAE-VDIV 580

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKRGS 1303
             +  K  L  +K    D  E+  VL +A    +    VV  + P    D E     +   
Sbjct: 581  VENDKLVLKFKKTEFQDSGEFKIVLENATGAEEHTTNVVFQDKPQAPQDIECTNIFQTRC 640

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
             V           P  ++++  + + K        D           + T    YK R++
Sbjct: 641  VVKWKAPVNDGGAPLTKYVLERQDVFKRSGWDKLEDVPGDQTKFSVTDLTPGRHYKFRVK 700

Query: 1364 --NNCGHAD---VEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
              N  G +D   +E ++   D   +P PP    I   D   +++ W  P++ G + I  Y
Sbjct: 701  AVNKMGESDYCSMEEDIIAKDPWNEPDPPRDLVISNWDKEFVDLAWKVPKSDGGAPIQSY 760

Query: 1416 VVEYQEIDTTEWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            +VEY+      W   + +  TQ  T+++NL    ++ FR  A N+   S  S +TE  K+
Sbjct: 761  IVEYKPYTAANWKQYETVGPTQLKTTVKNLTVGETFEFRVKATNQGGESKPSNSTEPLKI 820

Query: 1474 IKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGKKLKTA 1525
                +   P +E   +K IT +  + I     +GG P+P+V W +       D +K KT 
Sbjct: 821  --RDRYVKPFIEGDGIKPITLKKGQTIRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTI 878

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQ 1582
                                  YK    N  GE  T+    V+ +  +PV  I  E  + 
Sbjct: 879  DVE-SCATTLNVRHSVRADSGTYKLKLKNSSGEFVTAAKVLVLDVPSQPVGPIKIEKARS 937

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
             H V   W       G P    +  K   +     +      E+ +    + L++    +
Sbjct: 938  NHVV-ISWQPPEDTGGCPLTGYLLEKMDVENGTWLQAGECGPEQLT-FDFQHLQKGRKFE 995

Query: 1643 YTIEASNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            + ++A N  G S+ +E  L V     YD P  P  P +  +   + V ++W  P  DGG 
Sbjct: 996  FRVKAYNKEGESTPLETLLAVKTVNPYDPPEAPGKPAV-DDYGVDFVELKWAAPEKDGGR 1054

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALE- 1754
             +T Y IE        W + A  +   +T C +  L E   Y FRV A N  G S+  E 
Sbjct: 1055 PVTHYIIECKNKFMTDWGECAKTETP-DTVCKVHGLKEKVVYQFRVRAVNKGGTSKPSEP 1113

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK---QEGK 1811
            SE   +K     P           I      + W    K    P I +           +
Sbjct: 1114 SENHTVKHKNLKPRIDRTNLKNLTI-KVGKSMLWSVDVKGEPEPDISWSWRDNIPLTVSE 1172

Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
              K           I+      T +++I A N  G        + + +G    P      
Sbjct: 1173 NIKIETGNYHTNFSIKDAKRADTGKYKILATNASGKD--EAEVELVVLG---APGKCQGK 1227

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV--GGSVHEHCIEN 1929
              VS  T + + LKW +P  +GG PI  Y IE    +   W +  TV  G  + E  I  
Sbjct: 1228 LEVSNVTKKGLKLKWKKPLDDGGCPIKEYKIEKLKNRNGKWVRCGTVKGGPEILEADITG 1287

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
            + E     FR+   N  G S P ES+ V  +     P  P  P EI    +  V   W  
Sbjct: 1288 LDEGATYKFRVFGVNDEGESEPLESEEVVAKNPFDEPWKPGQP-EIVDFDNKSVKLKWAP 1346

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            P+ DGGAP+  Y I  ++  K  W +V +V  +     + DL EN     RI A N+ G 
Sbjct: 1347 PKSDGGAPITQYVIQKKERFKD-WEDVKEVPGHETTATVEDLKENTELQFRIVAVNKAGR 1405

Query: 2050 SEPLESDEPFKV 2061
            S   +     KV
Sbjct: 1406 SPESDPTATHKV 1417



 Score =  228 bits (557), Expect = 1e-57
 Identities = 197/792 (24%), Positives = 319/792 (40%), Gaps = 35/792 (4%)

Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            PPKI     R+  I  GS +   V+    P P  EW VN   +   +  +      ++  
Sbjct: 2905 PPKIDRRTIRDISISAGSMLKFDVNVSGEPAPKCEWRVNKATVSSDRRLEILNTDYNSKF 2964

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404
             ++     D+G Y++   N+ G   V + VT+ DKP  P  P  + ++   +  + W  P
Sbjct: 2965 ILRPANRNDSGDYEITATNSSGRDYVCVQVTVTDKPGAPEGPLQVSDVTKETCKLKWKRP 3024

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             + G   I YY +E  + D   W+      +T   I  L+    Y+   + V+ V+    
Sbjct: 3025 RDDGGCDIEYYQIERFDEDANAWVPHARSVETNADISGLQNGKKYK---FRVSAVNAEGE 3081

Query: 1465 SETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVP-QPKVTWYRD 1518
            S+  E     I +     P+  +  K     P + ++L  +     GG P    V   +D
Sbjct: 3082 SKPLEQVGDFIAKNPFDEPSAPQNCKATDWGP-DFVKLAWLPPISDGGSPITGYVVEVKD 3140

Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGI-----QQK 1570
              G+  K  +   +                 ++  A ND G    ++    I      Q 
Sbjct: 3141 KYGEWEKKMQVPAD-ATAAEVPDLMEGQKYEFRVRAVNDAGPGAPSNATPPIICKPKNQP 3199

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P I  +N  I  + K G+  +    + G P P   W  N  +L+ ++ + I   +  + I
Sbjct: 3200 PKIDRTNL-IDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKI 3258

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690
             I+   R  S  YTIEA N  G  +  V + V D PS P GP+ + EI+     +EW+ P
Sbjct: 3259 TIRSATRGESGTYTIEAENENGKDTATVFVTVLDVPSPPGGPLKVPEITANGAILEWRAP 3318

Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
             DDGGL +  Y IEK +     W+   D         I  L E   Y FRV AQN +G S
Sbjct: 3319 EDDGGLPIDNYIIEKLDEAKGTWVYAGDSGSSKCQAEIDGLIEGHSYKFRVRAQNKMGKS 3378

Query: 1751 EALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQ 1808
            E L  +  +V K     P            D + V + W   E +GG+PI  Y VE + +
Sbjct: 3379 EPLSMANAVVAKNPFRAPQ-RPENLTITDYDKDYVELEWKAPENDGGAPITGYVVEKLSK 3437

Query: 1809 EGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
                W+           A++  L   T YQFR+ A N  G        D         PP
Sbjct: 3438 YSGDWEKCAEVEGDACTAKVPDLIEGTAYQFRVKAINRAGEGEASKPTDSHIARSKNQPP 3497

Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
               R  + +      +T ++  P      P   +  +   +      K+V          
Sbjct: 3498 KIDRYSLSNVKIRAGLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYRTKLR- 3556

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            + ++K  D  ++ ++A+N  G+ +  +   V L+    VP+PP  P+    +    V   
Sbjct: 3557 VMDVKRSDSGVYTLTAKNKNGIDI-ADVNVVVLD----VPAPPEGPIRHENLSKTGVTLM 3611

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ DGG+ +L Y +   D  +  W+ VG+  ++T K    +L E H+Y  R+ A N+
Sbjct: 3612 WRPPKDDGGSEILHYVVEKLDTDQLRWIPVGET-IST-KIRPDNLIEGHSYQFRVRAVNK 3669

Query: 2047 IGLSEPLESDEP 2058
             G S PL + +P
Sbjct: 3670 QGESIPLSTSQP 3681



 Score =  223 bits (544), Expect = 6e-56
 Identities = 208/808 (25%), Positives = 331/808 (40%), Gaps = 51/808 (6%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
            IK G  +   VD +  P+P+  W     I +   ++ K    +   + +IK  +  D G 
Sbjct: 1138 IKVGKSMLWSVDVKGEPEPDISWSWRDNIPLTVSENIKIETGNYHTNFSIKDAKRADTGK 1197

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            YK+   N  G  + E+ + +L  P    GK  +  +    + + W +P + G   I  Y 
Sbjct: 1198 YKILATNASGKDEAEVELVVLGAPGKCQGKLEVSNVTKKGLKLKWKKPLDDGGCPIKEYK 1257

Query: 1417 VEYQEIDTTEWI---SVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
            +E  +    +W+   +VK   +  +  I  L   ++Y+FR + VN+   S+  E+ E   
Sbjct: 1258 IEKLKNRNGKWVRCGTVKGGPEILEADITGLDEGATYKFRVFGVNDEGESEPLESEE--- 1314

Query: 1473 VIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVP--QPKVTWYRDGKKLKTA 1525
            V+ +     P   KP +  I    N+ ++L        GG P  Q  +      K  +  
Sbjct: 1315 VVAKNPFDEPW--KPGQPEIVDFDNKSVKLKWAPPKSDGGAPITQYVIQKKERFKDWEDV 1372

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVIT-ISNEDIK 1581
            K    +                ++ +A N  G   E + +    ++ + +   I   ++K
Sbjct: 1373 KEVPGHETTATVEDLKENTELQFRIVAVNKAGRSPESDPTATHKVKHRALKPRIDRTNLK 1432

Query: 1582 QKHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS-H 1639
                 G + +   V ++G P PE+ W      +  D  Y I  K+  +   IK+  RS H
Sbjct: 1433 PIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNTKFTIKDSMRSKH 1492

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
            S  Y I A N  G    +V + V   PSKP+GP+ ++++++    ++WK P DDGG  +T
Sbjct: 1493 SGVYEIIAKNEHGMDKEKVEITVLASPSKPKGPLEVKDVTKNGCKLKWKKPEDDGGKPIT 1552

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP-I 1758
             Y +EK++    RW+ +     D E + +  L E   Y FRV A N  G SE LE+E   
Sbjct: 1553 GYQLEKYDQKVGRWVPIGKTPGDTEEFDVTGLQEGQHYKFRVKAINDEGESEPLETEEYT 1612

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXX 1817
            V K   D P            DN SV + W     +GG+PI  Y +E K+ G+ KW+   
Sbjct: 1613 VAKNPFDKPKAPTDLVINDW-DNSSVTLQWKRPSSDGGAPISGYFIEKKERGETKWEPAL 1671

Query: 1818 XXXX--XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                    A+I  L    TYQFR+ A N+ GT          T+      P   R  +  
Sbjct: 1672 TTYSPECQAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTP 1731

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
             +    +++++        +P         TVK     K V       ++ I+N+    +
Sbjct: 1732 ITIKAGLSVQYDIDIEGEPAP---------TVKWFHGDKEVVTDA---DYKIDNVDYNTK 1779

Query: 1936 IIFRISAENTVG--VSLPTESQSV-RLEKHATV---PSPPTAPLEIRMVGSNIVMTSWGT 1989
                    N  G    + T SQ   R E   T+   P  P  PLE   V  +     W  
Sbjct: 1780 FFIMRGRRNLSGKYTIVATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKP 1839

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            P  DGG P+ GY I   D     W+  G+   +T + NI  L E   Y  R+ A N+ G 
Sbjct: 1840 PLDDGGMPIDGYEIEKLDPLTGQWIPCGQ--SSTPEANISGLQEGKQYKFRVKAFNKEGD 1897

Query: 2050 SEPLESDEPFKVIPGEGSHADEEPGEQT 2077
            SEPLE +    VI  +      +PG  T
Sbjct: 1898 SEPLEMET--IVIAKDPFSEPSKPGRPT 1923



 Score =  202 bits (492), Expect = 1e-49
 Identities = 131/478 (27%), Positives = 216/478 (45%), Gaps = 14/478 (2%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQT 1438
            PS PG P ++++  S +++ W  P + G S I  Y VE ++I    W+     NI  T+ 
Sbjct: 5372 PSAPGAPAVIKVGKSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTEL 5431

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            +I NL     Y FR YAVN   +S  S  T   ++ ++   + P   K LK       + 
Sbjct: 5432 TITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGKS 5491

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFN 1554
            ++LTC   G P+P   W R+GK++    + A  +                   Y C A N
Sbjct: 5492 VQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALN 5551

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
              G + T+  V I   P +     D+      GD   +     G  P EV   K+  KL 
Sbjct: 5552 FVGAIHTTAAVKIGVPPKLVNIPSDVYLIK--GDNAKIKLGFSGDHPMEVNISKDREKLV 5609

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
              +    T  +  +VI I++++ S    Y +   N +G+ S  V + V   P  P GP++
Sbjct: 5610 ETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSGSVSCNVNVHVTGLPGPPTGPLL 5669

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
            +  +++   T+ WKPP  DGG ++T Y +E+ +  +  W+ V++  ++ +   I+ L E 
Sbjct: 5670 ISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIVSNYIKETQ-LIIKGLIEF 5728

Query: 1735 CEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
             EY+FRV A N  G    LE ++PI  +   D+PS          +  + V + W     
Sbjct: 5729 SEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPS-PPGIPIIHEVGGDFVNLEWDKPFS 5787

Query: 1794 NGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTS 1848
            +GG+ I+ Y +E +++G   W+           I    L     Y+FR+ A+NE+G S
Sbjct: 5788 DGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAAQNEVGCS 5845



 Score =  201 bits (491), Expect = 1e-49
 Identities = 172/704 (24%), Positives = 293/704 (41%), Gaps = 36/704 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKT 1436
            DKP  P    I + D+SS+ + W  P + G + I  Y +E +E   T+W         + 
Sbjct: 1619 DKPKAPTDLVINDWDNSSVTLQWKRPSSDGGAPISGYFIEKKERGETKWEPALTTYSPEC 1678

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495
            Q  I +L    +Y+FR  A+N+    +AS+ T ++ V  + +   P +++  L  IT + 
Sbjct: 1679 QAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTV--KHRYLRPRIDRTNLTPITIKA 1736

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYEN---RXXXXXXXXXXXXXXXYKCI 1551
               ++      G P P V W+   K++ T A    +N                   Y  +
Sbjct: 1737 GLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNLSGKYTIV 1796

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKN 1609
            A N  GE      + I  KP       +  + HK G +  W       G+P   +  Y+ 
Sbjct: 1797 ATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKPPLDDGGMP---IDGYEI 1853

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVY 1663
                    ++    +  T    I  L+     K+ ++A N  G S      ++ +    +
Sbjct: 1854 EKLDPLTGQWIPCGQSSTPEANISGLQEGKQYKFRVKAFNKEGDSEPLEMETIVIAKDPF 1913

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             +PSKP  P    +  ++ V +EW  P  DGG  +T+Y I+K +  + +W   A V  D 
Sbjct: 1914 SEPSKPGRPT-PTDWGKDFVDLEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGDR 1972

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
                ++ + E  EY FRVIA N  G SE  +    V+    ++            +    
Sbjct: 1973 TRGTVEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFG 2032

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839
              +          +P I ++++ K    +E ++ +           I+ L  + +  +++
Sbjct: 2033 QLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKV 2092

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPIT 1898
             A+N+ GT    T + ++ +   L  PS+      VS+ T+    L W  PE +GG P+ 
Sbjct: 2093 TAKNKNGTD---TVEMELVV---LAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQ 2146

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ-SV 1957
             Y++E   V    W ++        E  +  ++E  + +FR+ A N+ G S P E++ S 
Sbjct: 2147 AYVVERMDVDSGRWIQVCET--RFPEADVSGLQEGKDYMFRVKAVNSEGESEPLETETST 2204

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
            R +     PS P  P        + VM  W  PE DGGAP+  Y I  +D+  T WM+  
Sbjct: 2205 RAKNPYDAPSAPGKPKATDWSRKH-VMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAM 2263

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            + D    K  ++DL E  TY  R+ A N+ G S      +P  V
Sbjct: 2264 ETDGPVNKAKVQDLFEGTTYQFRVKAVNKGGPSPYSPLSDPVLV 2307



 Score =  201 bits (490), Expect = 2e-49
 Identities = 173/706 (24%), Positives = 303/706 (42%), Gaps = 42/706 (5%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKNITKT 1436
            +P+ P  P+I +I  +++ + W          I  Y+++Y+  D  +WI   S  ++   
Sbjct: 4678 RPNQPDPPSIDKISRNNVTLSWRTLRRDAKEKIKGYLIQYRIKDEDKWIDSNSAADLCSD 4737

Query: 1437 QT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTE 1494
            Q+  ++NL+ N  Y+FR  AVN++  SD S  +    VI + +   P ++ + +++IT  
Sbjct: 4738 QSYRVENLEENKEYQFRLIAVNDIGSSDPSRPS--ISVILQEQPNKPMMDLRNVRDITVR 4795

Query: 1495 PNEDIELTCIFGGVPQPKVTWYR-----DGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
              ED  +   +   P+P  TW+      D K  +  +   +                 Y+
Sbjct: 4796 AGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTRVHQQLTDEAAIFVVTNSKRTDSKQYR 4855

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWY 1607
             +  N  G    +C   +  +P      E+I  +   G+   +   A ++    P V  Y
Sbjct: 4856 LMLKNPSGYDIATCNAKVLDRPS---KPENIGVESYGGEHLTLCWNAPLDDGGSP-VTNY 4911

Query: 1608 KNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE-----VTLK 1661
                K +N   +  +++   T+ ++I+ L+ +   ++ + A N  G S        +   
Sbjct: 4912 VVERKEKNSSNWTKVSSYCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDTIIAKH 4971

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
             +D P++P  P  + E + +SVTI W  P  +GG  +T Y +EK       W KV     
Sbjct: 4972 PFDVPTQPGTPTRV-ETTEDSVTITWIKPASNGGSPITHYIVEKRPAAEGTWTKVQQGTL 5030

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXI- 1779
                  +  L EN EY+FRV A N  G S  +  S+PI++  A   P           + 
Sbjct: 5031 KDLMCKVSGLTENREYIFRVAAVNAAGQSPFSAASDPIMVTAAFTAPKITSDIGMRDILV 5090

Query: 1780 ---DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQ 1836
               D   + + +  S +     +++     + E  + +             K   + +Y 
Sbjct: 5091 IARDPFKIIVPFSASPRPDAFWLVNGNEVSRNERIELQVTDTEAIFKNDNAKRLDSGSYT 5150

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
              I+  N +G     ++  ++ +    TPP  P    VSE T  S TL W  P  +GGSP
Sbjct: 5151 --IHLVNCVGKD---SASCRVLVVDKPTPPIGPLE--VSEITPESCTLSWKVPLDDGGSP 5203

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            ITNYI+E     G  WTK  +   S H   +  ++   +  FR+ AEN  G+S P   + 
Sbjct: 5204 ITNYIVERYEPLGY-WTKASSFVRSTHYDNM-GMENNKQYSFRVRAENQYGISDPLILEE 5261

Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
              + ++  TVP PP  P  +    ++ V  +W  P  DGG+ + GY    RDVT + W+ 
Sbjct: 5262 PIIARYPFTVPDPPNPP-RVSDWDASYVTVTWERPLMDGGSRIQGYRFEYRDVTDSTWI- 5319

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            V    +    + + +L     Y  R+ A+N  G+S+P  S + FK+
Sbjct: 5320 VCNFLIKDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKI 5365



 Score =  199 bits (486), Expect = 6e-49
 Identities = 173/676 (25%), Positives = 279/676 (41%), Gaps = 29/676 (4%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            PE + RL+   V  G       E   K +   RW ++G EI       L        L I
Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHI 5534

Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
             +    D G+Y+CE    VG    TA + +  P     +    +++   N    L     
Sbjct: 5535 SNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFS-G 5593

Query: 1222 DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT- 1277
            D  ++V   K +  + +TE  K+T+  D     + IR   + D+  Y      D+ S + 
Sbjct: 5594 DHPMEVNISKDREKLVETEHIKYTVFDDYA--VIYIRDVEDSDKGVYLVNFKNDSGSVSC 5651

Query: 1278 KLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             + V V   P P        +  K    V+         +    ++V  + IK       
Sbjct: 5652 NVNVHVTGLPGPPTGPLLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIV 5711

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTI-----LDKPSPPGKPNIL 1390
            S   K   L IK +      ++++   N  G  A +E    I      D PSPPG P I 
Sbjct: 5712 SNYIKETQLIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSPPGIPIIH 5771

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSS 1448
            E+    +N+ WD+P + G + I+ Y +E +E  T  W  V  ++ +  +I   NL     
Sbjct: 5772 EVGGDFVNLEWDKPFSDGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRF 5831

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
            Y FR  A NEV  S+ S+ ++  K       + P V KPL  +T   N ++E  C   GV
Sbjct: 5832 YEFRVAAQNEVGCSEFSKASQLVKAEDPDICKPPEVVKPLNTLTCVQNRNVEFVCKITGV 5891

Query: 1509 PQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
            P+PK+TW++  +++ +    Y     +                Y C A N  G   T   
Sbjct: 5892 PRPKITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKSTKAS 5951

Query: 1565 VGIQQKPVITISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
            + I+  P + +            G+   +     G P P   W   G ++E+   Y+I T
Sbjct: 5952 LIIKSPPKLNVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIET 6011

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
            +E+ +V+ I++  +  S  YTI   N  G  + ++ +++ D P KP   + + +I  + V
Sbjct: 6012 RERHTVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKPRN-LTVDQIGLDHV 6070

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
            T+ W PP  DGG  +T Y +EK E   + WI+ A   R      I  L+   +Y FRV A
Sbjct: 6071 TLSWLPPSWDGGASITNYIVEKREVPLSTWIR-AGTTR-FNQLIIPHLSPGHQYEFRVFA 6128

Query: 1744 QNPVGFSEALESEPIV 1759
            +N  G SE  +   +V
Sbjct: 6129 ENVYGRSEPSDQTELV 6144



 Score =  194 bits (474), Expect = 2e-47
 Identities = 136/477 (28%), Positives = 214/477 (44%), Gaps = 16/477 (3%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKY 1643
            K G    +   I G P P   W  N  ++E D  E  +  ++  + + I  + R+H+  Y
Sbjct: 2327 KGGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTY 2386

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
             I+A N++G    + T+ V DKP+ PEGP+ +  + +E  +++W PPLDDGG+ +  Y +
Sbjct: 2387 EIKAENSSGYDEHQFTITVLDKPTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVPIDHYNV 2446

Query: 1704 EKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEP-IVIK 1761
            EK + +  RW+ V    R  +T+  +  L    EY+FRV A N  G SE L +E  I+ K
Sbjct: 2447 EKFDKETGRWVPVG---RTPDTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQFIMAK 2503

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXX 1818
               D P            D   + + W P   +GGSPI  Y VE ++ G  KW       
Sbjct: 2504 NPFDEPGKPGTPEAYDW-DRNFIELRWTPPVCDGGSPITKYIVEKREHGTIKWIRAAEVI 2562

Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                 A++ +L+    Y+F++ A NE G  +       IT      PP   R  + + S 
Sbjct: 2563 GNKCEAKVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPRKLPPKIDRRNLKNLSV 2622

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
            +      +    S   +P  ++ I  + V   +   I  V  +  +    N   +D   +
Sbjct: 2623 AIGEPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYN-SKFANTNPDRRDSGKY 2681

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
             I A N  G      + +VR     + PS P  PLE++ +  +     W  P+ DGG P+
Sbjct: 2682 VIKATNKFGTDQVEITVTVR-----SKPSAPEGPLEVKDMTKDSCRLEWQKPKDDGGVPI 2736

Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
              Y +   D    +WM  GKV+    +F +  L   H Y  R+ A N  G S+PLES
Sbjct: 2737 DHYVVEKFDPDNGIWMTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGESDPLES 2793



 Score =  192 bits (469), Expect = 7e-47
 Identities = 196/872 (22%), Positives = 361/872 (41%), Gaps = 54/872 (6%)

Query: 1227 VTWYKKKSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            +TW  K   I  ++ E+  L ++  K  LIIR     D   Y     +   T  +++E+V
Sbjct: 2049 ITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKNKNGTDTVEMELV 2108

Query: 1285 EF--PPKIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
                P K +   +   +   G  +  L       +P   ++V    +   +  +   +++
Sbjct: 2109 VLAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQAYVVERMDVDSGRWIQVC-ETR 2167

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEIDSS 1395
                 +  ++     +++++  N+ G ++ +E   +       D PS PGKP   +    
Sbjct: 2168 FPEADVSGLQEGKDYMFRVKAVNSEGESEPLETETSTRAKNPYDAPSAPGKPKATDWSRK 2227

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK--TQTSIQNLKTNSSYRFRA 1453
             + + W EPE+ G + I  Y++E ++I++T+W+          +  +Q+L   ++Y+FR 
Sbjct: 2228 HVMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAMETDGPVNKAKVQDLFEGTTYQFRV 2287

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPK 1512
             AVN+   S  S  ++   V+ + +   P +++  LKN+T +  + + L C   G P P 
Sbjct: 2288 KAVNKGGPSPYSPLSD--PVLVKDRFAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPT 2345

Query: 1513 VTWYRDGKKLKT----AKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
              W  +  +++      +  +E+ R               Y+  A N  G  E    + +
Sbjct: 2346 KYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITV 2405

Query: 1568 QQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-K 1624
              KP        +   HK G   +W       G+P    I + N  K + +    +   +
Sbjct: 2406 LDKPTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVP----IDHYNVEKFDKETGRWVPVGR 2461

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMREI 1678
               + + +  L+      + + A N  G S   S E  +     +D+P KP  P    + 
Sbjct: 2462 TPDTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQFIMAKNPFDEPGKPGTPEAY-DW 2520

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
             R  + + W PP+ DGG  +TKY +EK E    +WI+ A+V  +     + +LNE   Y 
Sbjct: 2521 DRNFIELRWTPPVCDGGSPITKYIVEKREHGTIKWIRAAEVIGNKCEAKVTELNEGEVYE 2580

Query: 1739 FRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG- 1796
            F+V A N  G     + S+PI  K     P           +     +   F  + +G  
Sbjct: 2581 FKVRAVNEAGPGVWSDHSKPITAKPRKLPPKIDRRNLKNLSVAIGEPF--GFDVKISGEP 2638

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINT--TYQFRIYARNEIGTSLPYTSD 1854
            +P +D+ +  +                ++    + +   + ++ I A N+ GT       
Sbjct: 2639 APDVDWTINDRMVTVTTTRTIDNVPYNSKFANTNPDRRDSGKYVIKATNKFGT------- 2691

Query: 1855 DKITIGKTL-TPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
            D++ I  T+ + PS P     V + T  S  L+W +P+ +GG PI +Y++E        W
Sbjct: 2692 DQVEITVTVRSKPSAPEGPLEVKDMTKDSCRLEWQKPKDDGGVPIDHYVVEKFDPDNGIW 2751

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTA 1971
                 V     E  +E +       FR+ A N  G S P ES    L K + +VP  P+A
Sbjct: 2752 MTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGESDPLESAGTYLAKDSFSVPDTPSA 2811

Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031
            P  +    ++ V+  W  P+ DGG+P+ GY I  +D    +W +  +    +    +  L
Sbjct: 2812 PTVVDWSENHAVL-KWPEPD-DGGSPITGYIIEKKDKYSPIWEKACETTSPSPTATVGGL 2869

Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             E + Y  R+ A N+ G S+P ++   F   P
Sbjct: 2870 VEGNEYQFRVIAVNKAGQSDPSDASRTFTAKP 2901



 Score =  192 bits (469), Expect = 7e-47
 Identities = 171/700 (24%), Positives = 281/700 (40%), Gaps = 47/700 (6%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT---KT 1436
            KP  PGKP +++   + + + W  P+  G S I  YVVE ++    +W      T   K 
Sbjct: 3690 KPDKPGKPVVVDWSDNYVTLEWSIPKKDGGSPITSYVVE-KKPRYGDWKFAGEFTELFKP 3748

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK-PLKNITTEP 1495
               I +L  +  Y FR  AVN+  +SD SE+++   ++ +++   P  +K  LK++    
Sbjct: 3749 HAKITDLVKDEEYEFRICAVNKAGVSDPSESSD--PIVCKSRFVPPHFDKNALKDLIVPV 3806

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
             + I         P    TW RDG    +  +  +  Y N                Y  I
Sbjct: 3807 GKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLI 3866

Query: 1552 AFNDHGEVETSCVVGIQQKP--------VITISNEDIKQKHKV----GDEWLVTAVIEGI 1599
              N  GE   S  V +  KP        +  I+ E    + K+    G   +   VIE +
Sbjct: 3867 VKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKM 3926

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
                  W   G       E +     K    R+K +     S+  +E+S+        V 
Sbjct: 3927 DMSRGTWSAAGMSTSLANEISRLIHNKRYSFRVKAVNEIGESE-PLESSHPI------VA 3979

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
               +++PS+P  P ++ +    SV++EW  P  DGG  +T+Y ++K E D+  W     V
Sbjct: 3980 KNDFEEPSQPPKPQVV-DWDANSVSLEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRV 4038

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
                    +  L    E+ FRVIA N  G SE  ++   V+  +  +            +
Sbjct: 4039 PGIQRNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVV 4098

Query: 1780 DNESVY--ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTY 1835
                ++     F  E    +P + + +  K      +           +  ++ N   + 
Sbjct: 4099 KAGLIFHLDVNFTGEP---APEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSG 4155

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             +++   N  GT         +T+     PP  P N+   E T +SVT+ W  P+ NGGS
Sbjct: 4156 DYKLKISNSSGTD---EGSLHLTVLDRPDPPEGPMNY--EEITEKSVTISWKPPKDNGGS 4210

Query: 1896 PITNYIIEFKTV-KGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTE 1953
             IT Y++E K +  G  W   V      + H  +  + + ++  FR+ AEN  G S    
Sbjct: 4211 EITGYVVEKKDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLM 4270

Query: 1954 SQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
            S+  V  +    VP PPT P +I     + +  SW  P  DGG+ + GYNI  RD     
Sbjct: 4271 SKHPVVAKDQFVVPGPPTKP-DITDSNYDFITLSWKPPISDGGSRISGYNIERRDTATGR 4329

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            W++  K  +  ++F    +   H Y  R+ A N  G  +P
Sbjct: 4330 WIQANKYPIPNIEFTDTGVMRGHQYDYRVSAVNAAGQGQP 4369



 Score =  188 bits (457), Expect = 2e-45
 Identities = 210/848 (24%), Positives = 335/848 (39%), Gaps = 80/848 (9%)

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
            +D  K  ++    +  D+ E   V+L A    + K+EV     K +  + +  +  G   
Sbjct: 1193 ADTGKYKILATNASGKDEAEVELVVLGAPGKCQGKLEVSNVTKKGLKLKWKKPLDDGGCP 1252

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI-YKLRL-- 1362
                  +     N +W+       +C   K   +   A +T       D G  YK R+  
Sbjct: 1253 IKEYKIEKLKNRNGKWV-------RCGTVKGGPEILEADIT-----GLDEGATYKFRVFG 1300

Query: 1363 ENNCGHAD-VEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             N+ G ++ +E    +     D+P  PG+P I++ D+ S+ + W  P++ G + I  YV+
Sbjct: 1301 VNDEGESEPLESEEVVAKNPFDEPWKPGQPEIVDFDNKSVKLKWAPPKSDGGAPITQYVI 1360

Query: 1418 EYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            + +E    +W  VK +   +T  ++++LK N+  +FR  AVN+   S  S+ T  +KV  
Sbjct: 1361 QKKE-RFKDWEDVKEVPGHETTATVEDLKENTELQFRIVAVNKAGRSPESDPTATHKV-- 1417

Query: 1476 ETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---- 1530
            + +   P +++  LK I     + +       G P+P++TW    K +  A   YE    
Sbjct: 1418 KHRALKPRIDRTNLKPIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPV-FADDHYEIINK 1476

Query: 1531 --NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD 1588
              N                Y+ IA N+HG  +    + +   P       ++K   K G 
Sbjct: 1477 DYNTKFTIKDSMRSKHSGVYEIIAKNEHGMDKEKVEITVLASPSKPKGPLEVKDVTKNGC 1536

Query: 1589 --EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
              +W       G P       K   K+        T  + T    +  L+     K+ ++
Sbjct: 1537 KLKWKKPEDDGGKPITGYQLEKYDQKVGRWVPIGKTPGD-TEEFDVTGLQEGQHYKFRVK 1595

Query: 1647 ASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
            A N  G      T    V    +DKP  P   +++ +    SVT++WK P  DGG  ++ 
Sbjct: 1596 AINDEGESEPLETEEYTVAKNPFDKPKAPT-DLVINDWDNSSVTLQWKRPSSDGGAPISG 1654

Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES----- 1755
            Y IEK E    +W              I  L E   Y FRV A N  G  EA +      
Sbjct: 1655 YFIEKKERGETKWEPALTTYSPECQAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHT 1714

Query: 1756 ------EPIVIKTALDVPSXXXXXXXXXXIDNE---SVYITWFPSEKNGGSPIIDYKVEI 1806
                   P + +T L   +          ID E   +  + WF  +K   +   DYK++ 
Sbjct: 1715 VKHRYLRPRIDRTNLTPITIKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTD-ADYKIDN 1773

Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
                 K+            I +   N + ++ I A N  G      ++ +ITI   L+ P
Sbjct: 1774 VDYNTKF-----------FIMRGRRNLSGKYTIVATNSQGED---RAEVEITI---LSKP 1816

Query: 1867 SQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
              P      SE       LKW  P  +GG PI  Y IE        W  I     S  E 
Sbjct: 1817 GTPEGPLEASEVHKHGCKLKWKPPLDDGGMPIDGYEIEKLDPLTGQW--IPCGQSSTPEA 1874

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVM 1984
             I  ++E  +  FR+ A N  G S P E +++ + K   + PS P  P      G + V 
Sbjct: 1875 NISGLQEGKQYKFRVKAFNKEGDSEPLEMETIVIAKDPFSEPSKPGRPTPTDW-GKDFVD 1933

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              W  P+ DGGAP+  Y I  RD +   W +   V  +  +  + D+ E H Y  R+ A 
Sbjct: 1934 LEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGDRTRGTVEDVEEGHEYEFRVIAV 1993

Query: 2045 NEIGLSEP 2052
            N+ G SEP
Sbjct: 1994 NKAGPSEP 2001



 Score =  154 bits (373), Expect = 3e-35
 Identities = 132/483 (27%), Positives = 203/483 (42%), Gaps = 24/483 (4%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            VG +      +E  P     W ++G  +   +            + I    R     YT+
Sbjct: 3806 VGKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTL 3865

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
               N+ G  S    + V DKPS PEGP+ +  I+ E   +EWK P DDGG  +T Y IEK
Sbjct: 3866 IVKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEK 3925

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764
             +     W   A +   +    I +L  N  Y FRV A N +G SE LE S PIV K   
Sbjct: 3926 MDMSRGTW-SAAGMSTSLANE-ISRLIHNKRYSFRVKAVNEIGESEPLESSHPIVAKNDF 3983

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXX--XXX 1821
            + PS           D  SV + W   + +GG+PI +Y V+ K+ +   W          
Sbjct: 3984 EEPSQPPKPQVVDW-DANSVSLEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRVPGIQ 4042

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSEST 1878
               ++  L+  T ++FR+ A N  G S P   SD  +T  + + P   +  R+ VV    
Sbjct: 4043 RNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGL 4102

Query: 1879 SRSVTLKWT-EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
               + + +T EP     +P   + +  K V+    T +  VG     H + N    D   
Sbjct: 4103 IFHLDVNFTGEP-----APEVVWTLNGKPVESDKRTTMTAVGHHTIVHTV-NCNRGDSGD 4156

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
            +++   N+ G    T+  S+ L      P PP  P+    +    V  SW  P+ +GG+ 
Sbjct: 4157 YKLKISNSSG----TDEGSLHLTV-LDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSE 4211

Query: 1998 LLGYNIAIRDVTK-TMWM-EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            + GY +  +D+T    W+  V  V        +  L++ + Y  R+ A N  G S+ L S
Sbjct: 4212 ITGYVVEKKDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLMS 4271

Query: 2056 DEP 2058
              P
Sbjct: 4272 KHP 4274



 Score =  132 bits (319), Expect = 1e-28
 Identities = 89/292 (30%), Positives = 132/292 (45%), Gaps = 6/292 (2%)

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW-KXXXXXXXX 1822
            +D P+          I  ES  ++W     +GGSPI +Y VE  +    W K        
Sbjct: 5169 VDKPTPPIGPLEVSEITPESCTLSWKVPLDDGGSPITNYIVERYEPLGYWTKASSFVRST 5228

Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
                  +  N  Y FR+ A N+ G S P   ++ I      T P  P    VS+  +  V
Sbjct: 5229 HYDNMGMENNKQYSFRVRAENQYGISDPLILEEPIIARYPFTVPDPPNPPRVSDWDASYV 5288

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            T+ W  P  +GGS I  Y  E++ V   +W  +       + + + N+    E  FR+ A
Sbjct: 5289 TVTWERPLMDGGSRIQGYRFEYRDVTDSTWI-VCNFLIKDNSYQVYNLVPGREYEFRVRA 5347

Query: 1943 ENTVGVSLPTESQSVRLEKHA--TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            +N  GVS P+ S S R + H   T PS P AP  I+ VG + V  SW  P  DGG+ + G
Sbjct: 5348 QNAAGVSKPSAS-SKRFKIHGKITPPSAPGAPAVIK-VGKSFVDLSWTPPASDGGSRITG 5405

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            Y +  RD+    W++  + ++   +  I +L E   Y  R+YA N  G+S P
Sbjct: 5406 YYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVSPP 5457



 Score =  118 bits (284), Expect = 2e-24
 Identities = 152/653 (23%), Positives = 255/653 (39%), Gaps = 40/653 (6%)

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKP 1387
            TK S   +S       +EN     +++R EN  G +D + +   I+ +     P PP  P
Sbjct: 5219 TKASSFVRSTHYDNMGMENNKQYSFRVRAENQYGISDPLILEEPIIARYPFTVPDPPNPP 5278

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446
             + + D+S + + W+ P   G S I  Y  EY+++  + WI    + K  +  + NL   
Sbjct: 5279 RVSDWDASYVTVTWERPLMDGGSRIQGYRFEYRDVTDSTWIVCNFLIKDNSYQVYNLVPG 5338

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVI-KETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
              Y FR  A N   +S  S +++ +K+  K T   +P     +K   +  +         
Sbjct: 5339 REYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAPGAPAVIKVGKSFVDLSWTPPASD 5398

Query: 1506 GGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG-- 1557
            GG    ++T Y    RD    +  K    N                Y  +  A N++G  
Sbjct: 5399 GG---SRITGYYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVS 5455

Query: 1558 --EVETSCV-VGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNG 1610
                ET  V +G Q   + T   E +K+       +G    +T    G P P   W +NG
Sbjct: 5456 PPSTETRSVRIGEQ---LDTEKPEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNG 5512

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
             ++ +  ++ + +K     + I  +       YT EA N  G       +K+   P    
Sbjct: 5513 KEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVN 5572

Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730
             P  +  I  ++  I+      D  +E+   + ++ +      IK    D D     I+ 
Sbjct: 5573 IPSDVYLIKGDNAKIKLGFS-GDHPMEVN-ISKDREKLVETEHIKYTVFD-DYAVIYIRD 5629

Query: 1731 LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
            + ++ + ++ V  +N  G   ++     V  T L  P           +      ++W P
Sbjct: 5630 VEDSDKGVYLVNFKNDSG---SVSCNVNVHVTGL--PGPPTGPLLISHVTKNMCTVSWKP 5684

Query: 1791 SEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSIN-TTYQFRIYARNEIGTS 1848
             + +GG  I  Y VE +  + + W            I K  I  + Y FR+ A NE G  
Sbjct: 5685 PKYDGGRKITHYVVERRDIKSQHWLIVSNYIKETQLIIKGLIEFSEYLFRVSAVNENGMG 5744

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
             P    D I        PS P   ++ E     V L+W +P S+GG+ I  Y IE +   
Sbjct: 5745 APLEGADPIKARGPYDLPSPPGIPIIHEVGGDFVNLEWDKPFSDGGTRILGYWIEKREQG 5804

Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVRLE 1960
              +W ++ TV  S+      N+ E     FR++A+N VG S     SQ V+ E
Sbjct: 5805 TDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAAQNEVGCSEFSKASQLVKAE 5857



 Score =  111 bits (267), Expect = 2e-22
 Identities = 107/448 (23%), Positives = 181/448 (40%), Gaps = 32/448 (7%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDK---PSKPEGPVIMREIS 1679
            K +  ++  L      ++ + A N AG S    +    K++ K   PS P  P +++ + 
Sbjct: 5326 KDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAPGAPAVIK-VG 5384

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
            +  V + W PP  DGG  +T Y +E+ +    RW+K  + +  V    I  L E   Y F
Sbjct: 5385 KSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEF 5444

Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            RV A N  G S  + E+  + I   LD   P              +SV +T    E +G 
Sbjct: 5445 RVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGKSVQLT---CEAHGK 5501

Query: 1797 -SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
              P   +    K+   G ++            I  ++      +   A N +G ++  T+
Sbjct: 5502 PEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALNFVG-AIHTTA 5560

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
              KI +   L         +  ++    +      P     S     ++E + +K     
Sbjct: 5561 AVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFSGDHPMEVNISKDREKLVETEHIK----- 5615

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAP 1972
               TV        I ++++ D+ ++ ++ +N  G      S S  +  H T +P PPT P
Sbjct: 5616 --YTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSG------SVSCNVNVHVTGLPGPPTGP 5667

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            L I  V  N+   SW  P++DGG  +  Y +  RD+    W+ V    +   +  I+ L 
Sbjct: 5668 LLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIVSNY-IKETQLIIKGLI 5726

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            E   Y+ R+ A NE G+  PLE  +P K
Sbjct: 5727 EFSEYLFRVSAVNENGMGAPLEGADPIK 5754



 Score =  106 bits (255), Expect = 6e-21
 Identities = 62/188 (32%), Positives = 94/188 (50%), Gaps = 5/188 (2%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            PP+ P   ++S  T    T+ W  P+ +GG  IT+Y++E + +K + W  IV+      +
Sbjct: 5663 PPTGP--LLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWL-IVSNYIKETQ 5719

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
              I+ + E  E +FR+SA N  G+  P E +  ++      +PSPP  P+ I  VG + V
Sbjct: 5720 LIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSPPGIPI-IHEVGGDFV 5778

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
               W  P  DGG  +LGY I  R+     W  V  V  +    N  +L E   Y  R+ A
Sbjct: 5779 NLEWDKPFSDGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAA 5838

Query: 2044 RNEIGLSE 2051
            +NE+G SE
Sbjct: 5839 QNEVGCSE 5846



 Score =  105 bits (252), Expect = 1e-20
 Identities = 121/479 (25%), Positives = 206/479 (43%), Gaps = 44/479 (9%)

Query: 726  KIKTGEKEPPQVIEPLKSMIVRQG-ESVILSAQVVGNPRPTITWCKNNKPVKALPT---K 781
            ++K  E++      PL  +  ++G E  ++       P     W      +   P    K
Sbjct: 153  QLKKVERKQDTFSRPLVDITCKEGREKKVIFECAFTKPNAKAKWMLRKDEIFTGPKYKFK 212

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
            ++GD +S  I+ P KV+D G YT++     GI+   A +TVEE     A+P   + +F +
Sbjct: 213  TEGDVYSCLIINP-KVEDSGKYTIEI---AGIS-CFAYLTVEE-----ADP---VYKFTK 259

Query: 842  ITVK-EKGTI----KLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITN 894
               K EKG I     L   V  +  P   W    ++ +  E   I ++ +G  + L+I N
Sbjct: 260  TLKKNEKGFITHDTHLECAVDNSLAPISWWKGETKLENDGEKYVIGKDLNG-TVTLIIKN 318

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
               E D+  Y C       K+    ++ I      F K L KS +     TV L C+  H
Sbjct: 319  SVLE-DADTYTCKIEKQTDKTE--TKLKILEYNYKFTKVL-KSQQLFVKDTVTLACELDH 374

Query: 955  TVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
             + T +W+   ++I   D  +II++GR            D G+ +C+    +T   + VK
Sbjct: 375  VLGTVEWFKGDEKIVESDKVQIIKDGRKHKLVLKDVAKADSGMYRCVSNADKTEAEIFVK 434

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH-IR 1072
                +F++KL+D    E    +L++++  E ADV +   GE    K ++ D    G    
Sbjct: 435  RP-NKFMKKLKDTTGDETKECVLDIQVQDEEADVQFFL-GETEIVKNDRIDIVSPGDGTW 492

Query: 1073 KLYIRNTSVHDEGEYSCIL--RDESCTAEVT------VVELPPEIITRLQNQKVNKGNKA 1124
            KL  +   + D GE +C+       CT +V         E+PP++ T  + +KV +    
Sbjct: 493  KLVYKKLELGDAGEITCVCGPLTSKCTLKVNKKETKPKFEVPPKVETPAKVEKVLEVPFT 552

Query: 1125 TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            T E   +K  A V  FK G  +     + + ++  K  LK    +  D+GE+   + N+
Sbjct: 553  TGESRQSKVTAKV--FKVGKPVT-PAEVDIVVENDKLVLKFKKTEFQDSGEFKIVLENA 608



 Score =  105 bits (252), Expect = 1e-20
 Identities = 71/291 (24%), Positives = 120/291 (41%), Gaps = 14/291 (4%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVE 1285
            +TW+K    I    ++ + SD     L I     +D  EYTC  ++       K   +++
Sbjct: 5896 ITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKSTKASLIIK 5955

Query: 1286 FPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             PPK+ +    +R       G ++ + + +  FP+P   W +  + I+   H       +
Sbjct: 5956 SPPKL-NVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETRER 6014

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
               LTI+     D+G Y + +EN  G    ++ + I D P  P    + +I    + + W
Sbjct: 6015 HTVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKPRNLTVDQIGLDHVTLSW 6074

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              P   G ++I  Y+VE +E+  + WI        Q  I +L     Y FR +A N    
Sbjct: 6075 LPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQLIIPHLSPGHQYEFRVFAENVYGR 6134

Query: 1462 SDASETTEY-------YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
            S+ S+ TE         K  K  K +     KP +    EP  D + T +F
Sbjct: 6135 SEPSDQTELVSLKDLGIKPAKRVKYELDENGKPKRQGKREPISDYD-TYVF 6184



 Score =  103 bits (248), Expect = 4e-20
 Identities = 90/353 (25%), Positives = 152/353 (43%), Gaps = 13/353 (3%)

Query: 1138 RWFK-DGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
            RW K + S I  +   I   I+G   + ++Y  +       S E  + +    L  E+P 
Sbjct: 5417 RWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPE 5476

Query: 1196 INFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
              +  RL +F LVP      LT E    P+ T    W +    I    +F L S     +
Sbjct: 5477 --WVKRL-KFSLVPLGKSVQLTCEAHGKPEPTC--RWLRNGKEITHGGQFALESKNGVFS 5531

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
            L I   T  D+ +YTC  L+          V +  PPK+V+   +  + +G +  + + +
Sbjct: 5532 LHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGF 5591

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
                        + + + + +H K ++    A + I+ VE++D G+Y +  +N+ G    
Sbjct: 5592 SGDHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSGSVSC 5651

Query: 1372 EMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
             +NV +   P PP  P ++  +  +   + W  P+  G   I +YVVE ++I +  W+ V
Sbjct: 5652 NVNVHVTGLPGPPTGPLLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIV 5711

Query: 1431 KN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
             N I +TQ  I+ L   S Y FR  AVNE  +    E  +  K      + SP
Sbjct: 5712 SNYIKETQLIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSP 5764



 Score =  103 bits (247), Expect = 5e-20
 Identities = 79/318 (24%), Positives = 138/318 (43%), Gaps = 26/318 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F ++L+     DG  +Q  C V G P PQI W +    +  S    + Y    +A+L 
Sbjct: 6802 PKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKS-GIASLR 6860

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I E+FPED+GT+ C AKN+ G  S+  +L V+      G                   ++
Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTG-----------RSGDKKGSMV 6909

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDM 688
            +   P  +K   + Y  +GS+++++C  +  P+P ++ WL    EI    +     + D+
Sbjct: 6910 KA--PIINKHTDSGYYKDGSEVVIKCN-ITCPDPFNVIWLHDNREIKNTPDFEYLNDGDV 6966

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            +     L I  +     GTYT  A N+ GE+     + +   +KE P   +   S+ V  
Sbjct: 6967 YS----LHIPEIFPEDAGTYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLD 7022

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYT 804
            G   + + +    P   + W K+ +P+     +       + ++ TI K    +D G Y 
Sbjct: 7023 GVKAVFTCETFDAP-TKLEWYKDGEPINESSNRYRFVKKDNKYTFTIAK-CSFEDIGQYQ 7080

Query: 805  LKAENSEGIAETSAVITV 822
            ++A   +G A  S  + V
Sbjct: 7081 VRAVTRQGDALASFSVNV 7098



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 68/283 (24%), Positives = 112/283 (39%), Gaps = 31/283 (10%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
            PP F    +++   +   ++L   V+ +P+P I W +N + ++ S+ I   +      L 
Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGIASLR 6860

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT------------------FVKH 933
            I  +  E DSG Y C A NS G++S   +  +DV+KV                     KH
Sbjct: 6861 INELFPE-DSGTYVCTAKNSMGETS--TQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKH 6917

Query: 934  LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
                Y  ++G  V+++C  +     +  W H+ +EI      E + +G            
Sbjct: 6918 TDSGYY-KDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFP 6976

Query: 992  XDVGVIKCIV--KDQE-----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
             D G   C    K  E     T T+L  ++  P F +      V +   A+   E     
Sbjct: 6977 EDAGTYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLDGVKAVFTCETFDAP 7036

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
              + W +DGE I    N+Y F K+ +     I   S  D G+Y
Sbjct: 7037 TKLEWYKDGEPINESSNRYRFVKKDNKYTFTIAKCSFEDIGQY 7079



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 61/225 (27%), Positives = 95/225 (42%), Gaps = 32/225 (14%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  V+ L          V+F C++ G PRP+ITW +    I     + MY D D +  L 
Sbjct: 5865 PEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGD-MHHLA 5923

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I +VF EDA  +TC A N  G  S+   LI+++P      ++ V                
Sbjct: 5924 INDVFGEDADEYTCRAVNKGGVKSTKASLIIKSP-----PKLNV---------------- 5962

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
               PP F       + D G +I ++      P+P   W  KGE+I    +  +    + H
Sbjct: 5963 ---PPRFR---DTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETR-ERH 6015

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
               +VL I +  +   GTYT+   N  G+ +  I ++I     +P
Sbjct: 6016 ---TVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKP 6057



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 66/260 (25%), Positives = 111/260 (42%), Gaps = 25/260 (9%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F+K+ K     +G  + L C +   P P I W   G+++   + I +  +S +    
Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGI---- 6856

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--------TGEKEPPQVIEPL--- 741
            + L+I  +     GTY   A N  GE S    L +K        +G+K+   V  P+   
Sbjct: 6857 ASLRINELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINK 6916

Query: 742  --KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKK 796
               S   + G  V++   +       + W  +N+ +K  P     +DGD +S+ I +   
Sbjct: 6917 HTDSGYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFP 6976

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             +D G YT +A N  G + +S  ITV     E  E P F      ++V + G   +    
Sbjct: 6977 -EDAGTYTCEAFNKGGESFSSCTITV---LGEQKESPTFAKFPASLSVLD-GVKAVFTCE 7031

Query: 857  TRNPVPSITWYRNNEIISPS 876
            T +    + WY++ E I+ S
Sbjct: 7032 TFDAPTKLEWYKDGEPINES 7051



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 34/220 (15%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSIT 790
            P  VI P +S    +G+S     +V+G   P +TW  NN+ +K       +  GD +   
Sbjct: 6529 PRFVIRP-QSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELKQSVKFMKRYAGDDYYF- 6586

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------------------EPT----- 826
            I+   K+ D G Y ++AEN  G  E    + V                    EP+     
Sbjct: 6587 IINRVKLDDRGEYIIRAENHYGAREEVIFLNVHPMSKQVPVYKPETHTVRKREPSPRPLW 6646

Query: 827  -EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
             EE+   P+F    +   ++ + T KL+  ++  PVP++ WY+N   +S  E    + DG
Sbjct: 6647 QEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHTDG 6706

Query: 886  -ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
               +E++ T V    DSG+YKCVA N  GK+   + V ++
Sbjct: 6707 VVTMEIIDTKVG---DSGEYKCVAINPLGKAETSSVVIVE 6743



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 53/196 (27%), Positives = 86/196 (43%), Gaps = 13/196 (6%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789
            +PP+V++PL ++   Q  +V    ++ G PRP ITW K  + +         SDGD H +
Sbjct: 5863 KPPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHL 5922

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG- 848
             I      +D   YT +A N  G+  T A + ++ P + N  P     RF++    + G 
Sbjct: 5923 AI-NDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPP-----RFRDTAFFDNGE 5976

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKCV 907
             I++    T  P P   W    E I        + +      V+T  D S++DSG Y   
Sbjct: 5977 NIEIKIPFTGFPKPRCHWTLKGEQIESGS--HYHIETRERHTVLTIRDGSQMDSGTYTIT 6034

Query: 908  ASNSAGKSSHGARVTI 923
              N  G+ +   ++ I
Sbjct: 6035 IENELGQDTADIKIQI 6050



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 18/256 (7%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
            PP+  + LK +I   GE + L+  V G+P P I W KN K + +           I  L+
Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGIASLR 6860

Query: 794  PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEEN----------AEPPLFINRFQE 841
              ++  +D G Y   A+NS G   T   + V++                + P+       
Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKHTDS 6920

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
               K+   + +   +T     ++ W  +N  I  +       DG+   L I  +  E D+
Sbjct: 6921 GYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFPE-DA 6979

Query: 902  GDYKCVASNSAGKSSHGARVTI---DVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVS 957
            G Y C A N  G+S     +T+     E  TF K    S    +G   +  C+T      
Sbjct: 6980 GTYTCEAFNKGGESFSSCTITVLGEQKESPTFAK-FPASLSVLDGVKAVFTCETFDAPTK 7038

Query: 958  TKWYHNKKEISGMDHR 973
             +WY + + I+   +R
Sbjct: 7039 LEWYKDGEPINESSNR 7054



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 52/222 (23%), Positives = 84/222 (37%), Gaps = 19/222 (8%)

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            D      T E   +  +  +  P   K LK++     E ++L C   G P P++ W ++G
Sbjct: 6780 DARSRQSTRELMPLQSDALMHPPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNG 6839

Query: 1520 KKLKTAKA---TYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            KKL ++      Y++                 Y C A N  GE  T C + +++    T 
Sbjct: 6840 KKLTSSDVIDIKYKSGIASLRINELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTG 6899

Query: 1576 SNEDIK---------QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             + D K          KH      K G E ++   I    P  VIW  +  +++N  ++ 
Sbjct: 6900 RSGDKKGSMVKAPIINKHTDSGYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFE 6959

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
                     + I E+    +  YT EA N  G S    T+ V
Sbjct: 6960 YLNDGDVYSLHIPEIFPEDAGTYTCEAFNKGGESFSSCTITV 7001



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 8/131 (6%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I +  + D   + I+ EN +G     ++  ++++  +  P  P   L +  +G + V  S
Sbjct: 6020 IRDGSQMDSGTYTITIENELG----QDTADIKIQI-SDCPDKPRN-LTVDQIGLDHVTLS 6073

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P WDGGA +  Y +  R+V  + W+  G    N L   I  LS  H Y  R++A N 
Sbjct: 6074 WLPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQL--IIPHLSPGHQYEFRVFAENV 6131

Query: 2047 IGLSEPLESDE 2057
             G SEP +  E
Sbjct: 6132 YGRSEPSDQTE 6142



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 8/155 (5%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            LK+ ++    E  + V+AVN  GE+  S      +       P+++ PL+ M+V+ G   
Sbjct: 4045 LKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGLIF 4104

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
             L     G P P + W  N KPV++    T +    H+I         D G Y LK  NS
Sbjct: 4105 HLDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKLKISNS 4164

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
             G  E S  +TV     +  +PP     ++EIT K
Sbjct: 4165 SGTDEGSLHLTV----LDRPDPPEGPMNYEEITEK 4195



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 8/117 (6%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            + I   NE+G     T+D KI I      P +PRN  V +     VTL W  P  +GG+ 
Sbjct: 6031 YTITIENELGQD---TADIKIQISDC---PDKPRNLTVDQIGLDHVTLSWLPPSWDGGAS 6084

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            ITNYI+E + V   +W +  T     ++  I ++    +  FR+ AEN  G S P++
Sbjct: 6085 ITNYIVEKREVPLSTWIRAGTT--RFNQLIIPHLSPGHQYEFRVFAENVYGRSEPSD 6139



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 62/279 (22%), Positives = 109/279 (39%), Gaps = 30/279 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P+F ++L+D    + +   L   ++ +    +VW ++G+ +    +  D + +  I  L 
Sbjct: 6802 PKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLT-SSDVIDIKYKSGIASLR 6860

Query: 1076 IRNTSVHDEGEYSCILRDE------SCTAEVTVVE-------------LPPEIITRLQNQ 1116
            I      D G Y C  ++        C  +V  V              +   II +  + 
Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKHTDS 6920

Query: 1117 KVNK-GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
               K G++   +  +T  D   V W  D  EI+ +   +   DG    L I +   +DAG
Sbjct: 6921 GYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFPEDAG 6980

Query: 1175 EYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228
             Y+CE  N      S CT  +  E+       + P  + V     A  T E  D    + 
Sbjct: 6981 TYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLDGVKAVFTCETFDAPTKLE 7040

Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            WYK  + + E + ++  +    K T  I KC+ +D  +Y
Sbjct: 7041 WYKDGEPINESSNRYRFVKKDNKYTFTIAKCSFEDIGQY 7079



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 5/96 (5%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            API  +     +  DGS V  +C +   P P  + W      IK + DF+ Y +D +V +
Sbjct: 6911 APIINKHTDSGYYKDGSEVVIKCNIT-CPDPFNVIWLHDNREIKNTPDFE-YLNDGDVYS 6968

Query: 568  LVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVE 601
            L I E+FPEDAGT+TC A N  G  F+S T  ++ E
Sbjct: 6969 LHIPEIFPEDAGTYTCEAFNKGGESFSSCTITVLGE 7004



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 17/278 (6%)

Query: 492  IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
            + K  + E      Q+ AP FV + +     +G + +F C+V G   P +TW+     +K
Sbjct: 6512 VTKYKIHETSFDRRQA-APRFVIRPQSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELK 6570

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD----H 607
             S  F   Y  D+    +I  V  +D G +   A+N  G       L V  P+S     +
Sbjct: 6571 QSVKFMKRYAGDDY-YFIINRVKLDDRGEYIIRAENHYGAREEVIFLNVH-PMSKQVPVY 6628

Query: 608  GSEMTVXXXXXXXXXXXXADILEGIPP-TFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
              E                +  +  P  TF+ +P+   + +   +L  C L   P P + 
Sbjct: 6629 KPETHTVRKREPSPRPLWQEESDAAPVFTFALRPRVMQMRDTCKLL--CCLSGKPVPTVK 6686

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIV 724
            W   G E+   E      +  + M     +I + K    G Y  VA+N  G  E S  ++
Sbjct: 6687 WYKNGRELSRYEYSMTHTDGVVTM-----EIIDTKVGDSGEYKCVAINPLGKAETSSVVI 6741

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
            ++ +  + E PQV     +M + + + +  +++ +G P
Sbjct: 6742 VEDRRHQSELPQVEVTKPTMKIPEPKPLPSASKSLGPP 6779



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 56/285 (19%), Positives = 110/285 (38%), Gaps = 11/285 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G+P P++ W+K   ++ +   Y + +      + I ++    + +YT  A N  G  S
Sbjct: 5888 ITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKS 5947

Query: 1656 VEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
             + +L +   P K   P   R+ +       IE K P          + ++  + ++   
Sbjct: 5948 TKASL-IIKSPPKLNVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSH 6006

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
              +   +R      I+  ++     + +  +N +G   A     I I    D P      
Sbjct: 6007 YHIETRERHT-VLTIRDGSQMDSGTYTITIENELGQDTA--DIKIQISDCPDKPRNLTVD 6063

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSIN 1832
                 I  + V ++W P   +GG+ I +Y VE ++     W            I  LS  
Sbjct: 6064 Q----IGLDHVTLSWLPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQLIIPHLSPG 6119

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
              Y+FR++A N  G S P    + +++      P++   + + E+
Sbjct: 6120 HQYEFRVFAENVYGRSEPSDQTELVSLKDLGIKPAKRVKYELDEN 6164



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 16/236 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEK---EPPQVIEPLKSMIVRQGE 750
            L ITN+ +     + V AVN  G +      + ++ GE+   E P+ ++ LK  +V  G+
Sbjct: 5431 LTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGK 5490

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            SV L+ +  G P PT  W +N K +        +S     S+ I      +DEG YT +A
Sbjct: 5491 SVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHI-SNVTYRDEGDYTCEA 5549

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G   T+A + +         PP  +N   ++ + +    K+    + +    +   
Sbjct: 5550 LNFVGAIHTTAAVKI-------GVPPKLVNIPSDVYLIKGDNAKIKLGFSGDHPMEVNIS 5602

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ++ E +  +E I      +   + I +V+ + D G Y     N +G  S    V +
Sbjct: 5603 KDREKLVETEHIKYTVFDDYAVIYIRDVE-DSDKGVYLVNFKNDSGSVSCNVNVHV 5657



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 42/133 (31%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 697  ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            + ++K+  E  + +VAVN+ G   E+      K+K    +P      LK ++VR G+ V 
Sbjct: 1384 VEDLKENTELQFRIVAVNKAGRSPESDPTATHKVKHRALKPRIDRTNLKPIVVRGGKMVH 1443

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
                V G P P ITW    KPV A         D +T   TI    + K  GVY + A+N
Sbjct: 1444 YDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNT-KFTIKDSMRSKHSGVYEIIAKN 1502

Query: 810  SEGIAETSAVITV 822
              G+ +    ITV
Sbjct: 1503 EHGMDKEKVEITV 1515



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 11/184 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP   K        +  ++   C++  +P P I W     EI       +  + DMH   
Sbjct: 5864 PPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHH-- 5921

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGE 750
              L I +V       YT  AVN+ G  S    L IK+  K   PP+  +   +     GE
Sbjct: 5922 --LAINDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPPRFRD---TAFFDNGE 5976

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAE 808
            ++ +     G P+P   W    + +++         + H++  ++     D G YT+  E
Sbjct: 5977 NIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETRERHTVLTIRDGSQMDSGTYTITIE 6036

Query: 809  NSEG 812
            N  G
Sbjct: 6037 NELG 6040



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 10/181 (5%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P + K+ K   V  G  + L C     PEP   WL  G+EI        A+ES   ++  
Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEIT--HGGQFALESKNGVFS- 5531

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I+NV    EG YT  A+N  G       +KI      PP+++     + + +G++  
Sbjct: 5532 -LHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGV----PPKLVNIPSDVYLIKGDNAK 5586

Query: 754  LSAQVVGNPRPTITWCKN-NKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            +     G+    +   K+  K V+    K +  D +++  ++  +  D+GVY +  +N  
Sbjct: 5587 IKLGFSGDHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDS 5646

Query: 812  G 812
            G
Sbjct: 5647 G 5647



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 57/227 (25%), Positives = 104/227 (45%), Gaps = 16/227 (7%)

Query: 699  NVKKFQEGTYTVVAVNREGEAS-LPIVLKIKT-GEKEPPQVIEPLKSMIVRQGESVI--- 753
            +++K ++  + V A N+EGE++ L  +L +KT    +PP+   P K  +   G   +   
Sbjct: 987  HLQKGRKFEFRVKAYNKEGESTPLETLLAVKTVNPYDPPEA--PGKPAVDDYGVDFVELK 1044

Query: 754  LSAQVVGNPRPT---ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT--LKAE 808
             +A      RP    I  CKN K +      +  +T   T+ K   +K++ VY   ++A 
Sbjct: 1045 WAAPEKDGGRPVTHYIIECKN-KFMTDWGECAKTETPD-TVCKVHGLKEKVVYQFRVRAV 1102

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-Y 867
            N  G ++ S          +N +P +     + +T+K   ++     V   P P I+W +
Sbjct: 1103 NKGGTSKPSEPSENHTVKHKNLKPRIDRTNLKNLTIKVGKSMLWSVDVKGEPEPDISWSW 1162

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            R+N  ++ SE I       +    I +     D+G YK +A+N++GK
Sbjct: 1163 RDNIPLTVSENIKIETGNYHTNFSIKDA-KRADTGKYKILATNASGK 1208



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 50/234 (21%), Positives = 86/234 (36%), Gaps = 33/234 (14%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  +P++ +  EG      CR++ +  P + W    +E+            D + +  
Sbjct: 6529 PRFVIRPQSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELKQSVKFMKRYAGDDYYFI- 6587

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLK-----------------IKTGEKEP-- 734
               I  VK    G Y + A N  G     I L                  ++  E  P  
Sbjct: 6588 ---INRVKLDDRGEYIIRAENHYGAREEVIFLNVHPMSKQVPVYKPETHTVRKREPSPRP 6644

Query: 735  ---------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
                     P     L+  +++  ++  L   + G P PT+ W KN + +          
Sbjct: 6645 LWQEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHT 6704

Query: 786  THSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838
               +T+ +   KV D G Y   A N  G AETS+V+ VE+   ++  P + + +
Sbjct: 6705 DGVVTMEIIDTKVGDSGEYKCVAINPLGKAETSSVVIVEDRRHQSELPQVEVTK 6758



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 11/135 (8%)

Query: 696  KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749
            ++ ++ + Q+  + V AVN  G      A+ PI+ K K    +PP++    L  + ++ G
Sbjct: 3159 EVPDLMEGQKYEFRVRAVNDAGPGAPSNATPPIICKPKN---QPPKIDRTNLIDVRIKAG 3215

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807
             +V+   +V G P PT  W  N + +K        D D ++   ++     + G YT++A
Sbjct: 3216 NNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKITIRSATRGESGTYTIEA 3275

Query: 808  ENSEGIAETSAVITV 822
            EN  G    +  +TV
Sbjct: 3276 ENENGKDTATVFVTV 3290



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P +V++L+    P G +VQ  C+  G P P   W R    I     F +    + V +L 
Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFAL-ESKNGVFSLH 5533

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I  V   D G +TC A N  G   +T  + +  P
Sbjct: 5534 ISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVP 5567



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 2/108 (1%)

Query: 497  VFEKPTSEEQSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555
            + +   ++ +++AP    K L  K    G  +  E  V G P PQITW  +   I   +D
Sbjct: 2004 ISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLNVEADVTGEPAPQITWELKGKPITGKED 2063

Query: 556  FQMYYDDDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             ++  D+++  T L+IR +   D+G +   AKN  G  +   EL+V A
Sbjct: 2064 ERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKNKNGTDTVEMELVVLA 2111



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 11/135 (8%)

Query: 696  KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQG 749
            KIT++ K +E  + + AVN+ G     E+S PIV K +     PP   +  LK +IV  G
Sbjct: 3751 KITDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRF---VPPHFDKNALKDLIVPVG 3807

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDE-GVYTLKA 807
            + +  +  V  +P  T TW ++   + ++     +   + +++  P  ++++ G+YTL  
Sbjct: 3808 KKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLIV 3867

Query: 808  ENSEGIAETSAVITV 822
            +NS G    S  +TV
Sbjct: 3868 KNSCGEYSASGHVTV 3882



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 8/136 (5%)

Query: 698  TNVKKFQEGTYTVVAVNR--EGEASLPIV-LKIKTGEKEPPQVIEPL--KSMIVRQGESV 752
            T V +  +  Y V AVN   +G+ S P      K  ++ P   ++    +++ VR GE +
Sbjct: 4346 TGVMRGHQYDYRVSAVNAAGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVRAGEPI 4405

Query: 753  ILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            I++  +VG P PT+ W +N    P  +  T      H++  ++  + KD   Y +KA N 
Sbjct: 4406 IITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKIKASNQ 4465

Query: 811  EG-IAETSAVITVEEP 825
             G       VI V+ P
Sbjct: 4466 YGEDTREFEVIVVDRP 4481



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 12/138 (8%)

Query: 700  VKKFQEGT---YTVVAVNREGEASL-PIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVI 753
            V+   EGT   + V AVN+ G +   P+   +   ++  P  I+   LK+M ++ G+S+ 
Sbjct: 2274 VQDLFEGTTYQFRVKAVNKGGPSPYSPLSDPVLVKDRFAPPRIDRSTLKNMTLKGGQSLR 2333

Query: 754  LSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  ++ G P PT  W  N   V+     +  + +     +TI    +  + G Y +KAEN
Sbjct: 2334 LDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHN-GTYEIKAEN 2392

Query: 810  SEGIAETSAVITV-EEPT 826
            S G  E    ITV ++PT
Sbjct: 2393 SSGYDEHQFTITVLDKPT 2410



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G P P V WYKNG +L    EY++T  +    + I + K   S +Y   A N  G + 
Sbjct: 6677 LSGKPVPTVKWYKNGRELSR-YEYSMTHTDGVVTMEIIDTKVGDSGEYKCVAINPLGKAE 6735

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
                + V D+  + E P +  E+++ ++ I    PL      L
Sbjct: 6736 TSSVVIVEDRRHQSELPQV--EVTKPTMKIPEPKPLPSASKSL 6776



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 7/123 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIV---LKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            + +V++  E  + V+AVN+ G +    +   +  K     P    + L   ++R G+ + 
Sbjct: 1977 VEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLN 2036

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAEN 809
            + A V G P P ITW    KP+     +     + D  +  I++  K  D G+Y + A+N
Sbjct: 2037 VEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKN 2096

Query: 810  SEG 812
              G
Sbjct: 2097 KNG 2099



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA-TLVIREVF 574
           ++P     G T+++  Q  G P P++ W +   +I    + +   D ++ A TL +R   
Sbjct: 834 IKPITLKKGQTIRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTIDVESCATTLNVRHSV 893

Query: 575 PEDAGTFTCVAKNAAG-FASSTTELIVEAP 603
             D+GT+    KN++G F ++   L+++ P
Sbjct: 894 RADSGTYKLKLKNSSGEFVTAAKVLVLDVP 923



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 6/136 (4%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749
            +V K+  +K+     + V AVN+ G +  S P        +   P++    LK++ ++ G
Sbjct: 1082 TVCKVHGLKEKVVYQFRVRAVNKGGTSKPSEPSENHTVKHKNLKPRIDRTNLKNLTIKVG 1141

Query: 750  ESVILSAQVVGNPRPTITWC-KNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLK 806
            +S++ S  V G P P I+W  ++N P+          G+ H+   +K  K  D G Y + 
Sbjct: 1142 KSMLWSVDVKGEPEPDISWSWRDNIPLTVSENIKIETGNYHTNFSIKDAKRADTGKYKIL 1201

Query: 807  AENSEGIAETSAVITV 822
            A N+ G  E    + V
Sbjct: 1202 ATNASGKDEAEVELVV 1217



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 11/135 (8%)

Query: 696  KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749
            K+T + + +   + V AVN  G     + S PI  K +   K PP++    LK++ V  G
Sbjct: 2569 KVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPR---KLPPKIDRRNLKNLSVAIG 2625

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPK-KVKDEGVYTLKA 807
            E      ++ G P P + W  N++ V    T++ D   ++          +D G Y +KA
Sbjct: 2626 EPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYNSKFANTNPDRRDSGKYVIKA 2685

Query: 808  ENSEGIAETSAVITV 822
             N  G  +    +TV
Sbjct: 2686 TNKFGTDQVEITVTV 2700



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 3/99 (3%)

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---EN 1531
            +E    +P     L+    +  +  +L C   G P P V WY++G++L   + +    + 
Sbjct: 6647 QEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHTDG 6706

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
                            YKC+A N  G+ ETS VV ++ +
Sbjct: 6707 VVTMEIIDTKVGDSGEYKCVAINPLGKAETSSVVIVEDR 6745



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 18/209 (8%)

Query: 633  PPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP   +   K   +  G  + L+C++   P P   WL     +  D N  + +E     Y
Sbjct: 2313 PPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPTKYWLLNKARVEKD-NPEIRVE--FEDY 2369

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGE 750
             + L I  V +   GTY + A N  G       + +     +P     PLK S + ++G 
Sbjct: 2370 RAKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITVL---DKPTAPEGPLKVSNVHKEGC 2426

Query: 751  SVILSAQV--VGNPRPTITWCKNNKPV-KALPTKSDGDTH-SITILKPKKVKDEGVYTLK 806
            S+  +  +   G P       K +K   + +P     DTH  +T L+P +   E ++ + 
Sbjct: 2427 SLKWNPPLDDGGVPIDHYNVEKFDKETGRWVPVGRTPDTHMDVTNLEPGQ---EYLFRVS 2483

Query: 807  AENSEGIAE---TSAVITVEEPTEENAEP 832
            A N EG++E   T   I  + P +E  +P
Sbjct: 2484 AVNDEGVSEPLSTEQFIMAKNPFDEPGKP 2512



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 6/165 (3%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            PE++++L+   V       L  E + +      W R+G+ I     ++  E +  +  L+
Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEIT-HGGQFALESKNGVFSLH 5533

Query: 1076 IRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132
            I N +  DEG+Y+C   +      T     + +PP+++    +  + KG+ A  ++  + 
Sbjct: 5534 ISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFSG 5593

Query: 1133 GDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
               + V   KD  ++  + HI+ T+      + I D +  D G Y
Sbjct: 5594 DHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVY 5638



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 4/140 (2%)

Query: 789  ITILKPKKVKDEGVYTLK--AENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVK 845
            +T L    + + GVY  +  A N+ G++  S    +V    + + E P ++ R +   V 
Sbjct: 5428 VTELTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVP 5487

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
               +++L       P P+  W RN + I+               L I+NV    D GDY 
Sbjct: 5488 LGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYR-DEGDYT 5546

Query: 906  CVASNSAGKSSHGARVTIDV 925
            C A N  G     A V I V
Sbjct: 5547 CEALNFVGAIHTTAAVKIGV 5566



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 6/148 (4%)

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIE-PLKSMIVRQGESVILSAQVVGN 761
            E  + V+AVN+ G++      +  T +    PP++    ++ + +  G  +     V G 
Sbjct: 2874 EYQFRVIAVNKAGQSDPSDASRTFTAKPRFAPPKIDRRTIRDISISAGSMLKFDVNVSGE 2933

Query: 762  PRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            P P   W  N   V +       + D +S  IL+P    D G Y + A NS G       
Sbjct: 2934 PAPKCEWRVNKATVSSDRRLEILNTDYNSKFILRPANRNDSGDYEITATNSSGRDYVCVQ 2993

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEK 847
            +TV +      E PL ++   + T K K
Sbjct: 2994 VTVTDKPGA-PEGPLQVSDVTKETCKLK 3020



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 21/87 (24%), Positives = 38/87 (43%)

Query: 516  LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575
            L+P     G  V ++  V+G P P+ITW  +   +     +++   D N    +   +  
Sbjct: 1431 LKPIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNTKFTIKDSMRS 1490

Query: 576  EDAGTFTCVAKNAAGFASSTTELIVEA 602
            + +G +  +AKN  G      E+ V A
Sbjct: 1491 KHSGVYEIIAKNEHGMDKEKVEITVLA 1517



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + +E  +   P P I W  KG+ I   E+  + ++++   Y + L I N+K+   G 
Sbjct: 2032 GQLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNED--YKTNLIIRNLKRSDSGI 2089

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
            Y V A N+ G  ++ + L +     +P + + PLK
Sbjct: 2090 YKVTAKNKNGTDTVEMELVVLA---KPSKCMGPLK 2121



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 42/195 (21%), Positives = 75/195 (38%), Gaps = 13/195 (6%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PPE++  L      +     F  ++T      + W K   EI   +   +  DG    L 
Sbjct: 5864 PPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHLA 5923

Query: 1165 IYDCDLDDAGEYSCEV---GNSKCT--AILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            I D   +DA EY+C     G  K T  +++    P +N   R  +      +    + ++
Sbjct: 5924 INDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPPRFRDTAFF--DNGENIEIK 5981

Query: 1220 IPDETLD---VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AK 1274
            IP          W  K   IE    + + +  +   L IR  ++ D   YT  + +   +
Sbjct: 5982 IPFTGFPKPRCHWTLKGEQIESGSHYHIETRERHTVLTIRDGSQMDSGTYTITIENELGQ 6041

Query: 1275 STTKLKVEVVEFPPK 1289
             T  +K+++ + P K
Sbjct: 6042 DTADIKIQISDCPDK 6056



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 1/125 (0%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            +E  + + A N  G ++ S            A P +     ++I++     +K    V+ 
Sbjct: 2873 NEYQFRVIAVNKAGQSDPSDASRTFTAKPRFAPPKIDRRTIRDISISAGSMLKFDVNVSG 2932

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P   W  N   +S    +       N + ++   +   DSGDY+  A+NS+G+    
Sbjct: 2933 EPAPKCEWRVNKATVSSDRRLEILNTDYNSKFILRPANRN-DSGDYEITATNSSGRDYVC 2991

Query: 919  ARVTI 923
             +VT+
Sbjct: 2992 VQVTV 2996



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 35/139 (25%), Positives = 55/139 (39%), Gaps = 3/139 (2%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A N  G +E S +         N  P +      +  ++    + + A VT  P P ITW
Sbjct: 1992 AVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLNVEADVTGEPAPQITW 2051

Query: 867  YRNNEIISPSETITQNFDGENIE--LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
                + I+  E      D E+ +  L+I N+    DSG YK  A N  G  +    + + 
Sbjct: 2052 ELKGKPITGKEDERIRLDNEDYKTNLIIRNL-KRSDSGIYKVTAKNKNGTDTVEMELVVL 2110

Query: 925  VEKVTFVKHLQKSYETEEG 943
             +    +  L+ S  T EG
Sbjct: 2111 AKPSKCMGPLKVSDVTAEG 2129



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 2/112 (1%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + L A N  G ++ S         E+  +P + +   ++ITV+      +    T  P P
Sbjct: 4753 FRLIAVNDIGSSDPSRPSISVILQEQPNKPMMDLRNVRDITVRAGEDFNIHIPYTAFPKP 4812

Query: 863  SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
              TW+ N+E +   +T + Q    E    V+TN     DS  Y+ +  N +G
Sbjct: 4813 VATWFANDEQLDDKDTRVHQQLTDEAAIFVVTN-SKRTDSKQYRLMLKNPSG 4863



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 55/248 (22%), Positives = 96/248 (38%), Gaps = 12/248 (4%)

Query: 691  YCSV--LKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            YC+   LKI N++  Q+  + V A N+ G  E +    +  K     P Q   P +    
Sbjct: 4929 YCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDTIIAKHPFDVPTQPGTPTRVETT 4988

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKD--EGVY 803
                ++           P   +    +P  +   TK    T    + K   + +  E ++
Sbjct: 4989 EDSVTITWIKPASNGGSPITHYIVEKRPAAEGTWTKVQQGTLKDLMCKVSGLTENREYIF 5048

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVP 862
             + A N+ G +  SA       T     P +  +   ++I V  +   K++   + +P P
Sbjct: 5049 RVAAVNAAGQSPFSAASDPIMVTAAFTAPKITSDIGMRDILVIARDPFKIIVPFSASPRP 5108

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARV 921
               W  N   +S +E I       + E +  N +++ +DSG Y     N  GK S   RV
Sbjct: 5109 DAFWLVNGNEVSRNERI--ELQVTDTEAIFKNDNAKRLDSGSYTIHLVNCVGKDSASCRV 5166

Query: 922  TIDVEKVT 929
             + V+K T
Sbjct: 5167 LV-VDKPT 5173



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 11/141 (7%)

Query: 698 TNVKKFQEGT---YTVVAVNREGEA---SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
           T VK    G    + V A N+ GE+   +    LKI+    +P    + +K + +++G++
Sbjct: 785 TTVKNLTVGETFEFRVKATNQGGESKPSNSTEPLKIRDRYVKPFIEGDGIKPITLKKGQT 844

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVK-DEGVYTLKA 807
           +    Q  G P P + W K++  +     K    D ++ + T+     V+ D G Y LK 
Sbjct: 845 IRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTIDVESCATTLNVRHSVRADSGTYKLKL 904

Query: 808 ENSEGIAETSA-VITVEEPTE 827
           +NS G   T+A V+ ++ P++
Sbjct: 905 KNSSGEFVTAAKVLVLDVPSQ 925



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 40/173 (23%), Positives = 73/173 (42%), Gaps = 13/173 (7%)

Query: 665  IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLP 722
            I +  K E+   D N +  + SD        ++ N+++ +E  + ++AVN  G +  S P
Sbjct: 4715 IQYRIKDEDKWIDSNSAADLCSDQSY-----RVENLEENKEYQFRLIAVNDIGSSDPSRP 4769

Query: 723  IVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
             +  I   +   P + +  ++ + VR GE   +       P+P  TW  N++ +    T+
Sbjct: 4770 SISVILQEQPNKPMMDLRNVRDITVRAGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTR 4829

Query: 782  SD---GDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEEPTEEN 829
                  D  +I ++   K  D   Y L  +N  G  IA  +A +       EN
Sbjct: 4830 VHQQLTDEAAIFVVTNSKRTDSKQYRLMLKNPSGYDIATCNAKVLDRPSKPEN 4882



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%)

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
            A P PD  WL  G E+  +E I + + +D     ++ K  N K+   G+YT+  VN  G+
Sbjct: 5104 ASPRPDAFWLVNGNEVSRNERIELQV-TDTE---AIFKNDNAKRLDSGSYTIHLVNCVGK 5159

Query: 719  AS 720
             S
Sbjct: 5160 DS 5161



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 51/241 (21%), Positives = 98/241 (40%), Gaps = 23/241 (9%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            +T +++ Q   + V A+N EGE+  P+  +  T  K P    +    +++   ++  ++ 
Sbjct: 1581 VTGLQEGQHYKFRVKAINDEGESE-PLETEEYTVAKNPFDKPKAPTDLVINDWDNSSVTL 1639

Query: 757  QVVGNPRPTITWCKNNKPVKA--LPTKSDGDTH---SITILKPK---KVKD---EGVYTL 805
            Q     RP+        P+    +  K  G+T    ++T   P+   K+ D   +  Y  
Sbjct: 1640 QW---KRPS---SDGGAPISGYFIEKKERGETKWEPALTTYSPECQAKIPDLPEKRTYQF 1693

Query: 806  K--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            +  A N  G  E S              P +       IT+K   +++    +   P P+
Sbjct: 1694 RVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTPITIKAGLSVQYDIDIEGEPAPT 1753

Query: 864  ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            + W+  + E+++ ++    N D  N +  I      + SG Y  VA+NS G+      +T
Sbjct: 1754 VKWFHGDKEVVTDADYKIDNVD-YNTKFFIMRGRRNL-SGKYTIVATNSQGEDRAEVEIT 1811

Query: 923  I 923
            I
Sbjct: 1812 I 1812



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 516  LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575
            L P     G +VQ++  +EG P P + WF     +    D+++   D N    ++R    
Sbjct: 1729 LTPITIKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRG-RR 1787

Query: 576  EDAGTFTCVAKNAAGFASSTTELIV 600
              +G +T VA N+ G   +  E+ +
Sbjct: 1788 NLSGKYTIVATNSQGEDRAEVEITI 1812



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 2/122 (1%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + +KA N  G +  S +       +  A P +  +  + +T+K   +++L  +++  P P
Sbjct: 2285 FRVKAVNKGGPSPYSPLSDPVLVKDRFAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAP 2344

Query: 863  SITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            +  W  N   +   +  I   F+    +L I  V +   +G Y+  A NS+G   H   +
Sbjct: 2345 TKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGV-TRAHNGTYEIKAENSSGYDEHQFTI 2403

Query: 922  TI 923
            T+
Sbjct: 2404 TV 2405



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ V F+ +V G P P   W      +K ++ F++  D D    + IR     ++GT+T 
Sbjct: 3215 GNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQ-DYDYNTKITIRSATRGESGTYTI 3273

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
             A+N  G  ++T  + V    S  G  + V
Sbjct: 3274 EAENENGKDTATVFVTVLDVPSPPGGPLKV 3303



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 522  PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            P G  + +   VE  P    TW R   +I  SQ   +    +N  +L I     ED G +
Sbjct: 3805 PVGKKIAYNVTVEASPNVTATWKRDGVVIPESQRV-IREAYNNEVSLEIPFSIREDCGMY 3863

Query: 582  TCVAKNAAG-FASSTTELIVEAPLSDHG 608
            T + KN+ G +++S    +++ P    G
Sbjct: 3864 TLIVKNSCGEYSASGHVTVLDKPSPPEG 3891



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 5/132 (3%)

Query: 696  KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESV 752
            KI ++ + +   + V A+N+ G  EAS P            P++    L  + ++ G SV
Sbjct: 1681 KIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTPITIKAGLSV 1740

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDG-DTHSITILKPKKVKDEGVYTLKAENS 810
                 + G P PT+ W   +K V      K D  D ++   +   +    G YT+ A NS
Sbjct: 1741 QYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNLSGKYTIVATNS 1800

Query: 811  EGIAETSAVITV 822
            +G       IT+
Sbjct: 1801 QGEDRAEVEITI 1812



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 3/97 (3%)

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGE 886
            +N  P +      ++ +K    +    +VT  P+P+  W  N   +  +E    Q++D  
Sbjct: 3196 KNQPPKIDRTNLIDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYD-Y 3254

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            N ++ I +  +  +SG Y   A N  GK +    VT+
Sbjct: 3255 NTKITIRSA-TRGESGTYTIEAENENGKDTATVFVTV 3290



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 2/86 (2%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T +F+  V+G P P   W  +  +I  +   ++ Y++     L + +V   D+G +T 
Sbjct: 3512 GLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYR-TKLRVMDVKRSDSGVYTL 3570

Query: 584  VAKNAAGFASSTTELIV-EAPLSDHG 608
             AKN  G   +   ++V + P    G
Sbjct: 3571 TAKNKNGIDIADVNVVVLDVPAPPEG 3596


>UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whole
            genome shotgun sequence; n=488; root|Rep: Chromosome
            undetermined SCAF15134, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 10495

 Score =  268 bits (656), Expect = 1e-69
 Identities = 263/1086 (24%), Positives = 443/1086 (40%), Gaps = 62/1086 (5%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PPTF+K  +    + G+D  L+C++       IAW     EI          +     +
Sbjct: 7400 MPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKD----H 7455

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L+I  ++K   G Y   A N  G       L +K    EPP          V  G +
Sbjct: 7456 SATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVK----EPPTFTVKPDGQDVIPGST 7511

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V   A   G    T+ W K +K + +  T   K D  + S+  L+  K  D   Y  +  
Sbjct: 7512 VSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLE-LQAVKPSDSARYACQVS 7570

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867
            N  G  + +A++ V+EP       P F+ + +  T+   G + +L  R T +PV    W+
Sbjct: 7571 NDAGKVDCTALLFVKEP-------PTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWF 7623

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++   I+P    T   D     L I    +  +SGDY CVAS+ AG       VT+    
Sbjct: 7624 KDEMEITPGPKYTMAADDLVASLEIVQC-TLAESGDYVCVASSEAGSDCCRGTVTVKAPP 7682

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXX 985
             +FV+ L+ S +  +G  ++LE Q S +   +     N K I       I  +       
Sbjct: 7683 -SFVRSLE-SKDVVKGSELMLEGQVSGSAPFTVTLCKNGKAIRNDKRHRITVKDELIALQ 7740

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE-VKEKDVAILEVEIN 1041
                   DVG+ +C V++Q          T+   P F++KL++   +   +V++L V   
Sbjct: 7741 VLAVEAGDVGLYQCTVENQVGRVSCDCHVTLKDPPSFVQKLENLSSLVGSEVSLLCVLKG 7800

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CT 1097
            SE   V W +D   +K  ++        +   L+I +   +  G+YSC  ++++    C+
Sbjct: 7801 SEPMVVSWMKDNHELKEAEH-IQITYESNTALLHITDVQRNHAGKYSCQAQNQAGSQTCS 7859

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
            A +TV E P EI    ++  V +G+ AT E   +    L   W K G E+      ++  
Sbjct: 7860 ALLTVKE-PAEITDEAKSISVTQGDPATLEARFSGTKPLRAMWIKAGKELISGQRYKVLS 7918

Query: 1157 DGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI--NFTLRLPEFILVPA 1210
                  LKI   D  D GEY    S +VG S C   LT+ +  I  +FT +L +   + A
Sbjct: 7919 TDSSSVLKINKTDKSDGGEYTFRVSNDVGQSSCEVTLTILDQIIPPSFTRKLKQTEGIKA 7978

Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
            +  A+L   +     + V WYK    I+   K           L I      D   YTC+
Sbjct: 7979 SF-AHLECLVSGSLPITVHWYKDDKEIQADHKHKCTFFENVAFLEISDLDSKDGGSYTCI 8037

Query: 1270 LLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
              +     +   + +V+ PP I++      +  GS V   V     P    +W  N K I
Sbjct: 8038 AKNKAGAVQCSAILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEI 8097

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
                      D+ S SL +   +++D+G Y+  ++N+ G    +  + + + P     P 
Sbjct: 8098 LSSADCSVIKDNTSTSLALFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEPPKFTRTPA 8157

Query: 1389 ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446
             + +     N  + E + TG   I +Y+  E  EI  +E   +  +    +  +   +T 
Sbjct: 8158 RVSVTRLGQNKVF-ECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLASLEVCGTETK 8216

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
             S  +   A NE      SE+      +KE     PT+ K L       +    L C   
Sbjct: 8217 DSGLYYCEARNEA----GSESCSMELKVKEI----PTIIKDLAPAELVKDSTAHLECQVT 8268

Query: 1507 GVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXX---XXXXXXYKCIAFNDHGEVETS 1562
            G    +VTWYRD K++K+ AK ++                     Y+C   N+ G   + 
Sbjct: 8269 GTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCTSK 8328

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
              + +++ P  T   E+      +G   +   V+EG P   V W K+ N +  D +   T
Sbjct: 8329 ATLKLKEPPTFTKKLENTDTV--LGKMAVFQCVVEGSPTLSVQWQKDDNWILEDPKIERT 8386

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
             +   ++++I   +  HS KY+ +  N AG +    TL V + P   E P +++    + 
Sbjct: 8387 FENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQEPPQITEKPEVIKVTVGDP 8446

Query: 1683 VTIEWK 1688
            V+++ K
Sbjct: 8447 VSLDCK 8452



 Score =  219 bits (534), Expect = 9e-55
 Identities = 248/1066 (23%), Positives = 423/1066 (39%), Gaps = 76/1066 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PPTF+ KP  Q V  GS +             + W  + +EIV      +  ++      
Sbjct: 7494 PPTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATS---- 7549

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGES 751
            S L++  VK      Y     N  G+     +L +K    EPP  +  L++  +V  G+S
Sbjct: 7550 SSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVK----EPPTFVRKLEATTLVTCGQS 7605

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
              L  +  G+P     W K+   +   P  T +  D  +   +    + + G Y   A +
Sbjct: 7606 SRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASS 7665

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G       +TV+ P       P F+   +   V +   + L  +V+ +   ++T  +N
Sbjct: 7666 EAGSDCCRGTVTVKAP-------PSFVRSLESKDVVKGSELMLEGQVSGSAPFTVTLCKN 7718

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + I   +        E I L +  V++  D G Y+C   N  G+ S    VT+  +  +
Sbjct: 7719 GKAIRNDKRHRITVKDELIALQVLAVEAG-DVGLYQCTVENQVGRVSCDCHVTLK-DPPS 7776

Query: 930  FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            FV+ L+ +  +  G  V L C  + S  +   W  +  E+   +H +I  E         
Sbjct: 7777 FVQKLE-NLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITYESNTALLHIT 7835

Query: 988  XXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042
                   G   C  ++Q      S +L VKE   E   + +   V + D A LE   + +
Sbjct: 7836 DVQRNHAGKYSCQAQNQAGSQTCSALLTVKEPA-EITDEAKSISVTQGDPATLEARFSGT 7894

Query: 1043 ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097
            +    +W + G E+I  ++ K        + K  I  T   D GEY+  + ++    SC 
Sbjct: 7895 KPLRAMWIKAGKELISGQRYKVLSTDSSSVLK--INKTDKSDGGEYTFRVSNDVGQSSCE 7952

Query: 1098 AEVTVVE--LPPEIITRLQNQKVNKGNKATF-EIELTKGDAL---VRWFKDGSEIQFSNH 1151
              +T+++  +PP    +L   K  +G KA+F  +E     +L   V W+KD  EIQ  + 
Sbjct: 7953 VTLTILDQIIPPSFTRKL---KQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQADHK 8009

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
             + T       L+I D D  D G Y+C    + G  +C+AIL V+EP     L  PE + 
Sbjct: 8010 HKCTFFENVAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEPPC--ILEKPESMN 8067

Query: 1208 VPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            V   +  +  V +     L + W+K +  I  +   ++I D    +L +      D  EY
Sbjct: 8068 VLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSLALFFAKSSDSGEY 8127

Query: 1267 TCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVN 1324
             C +  D  ST+      V+ PPK         + R G +          P+ +  W   
Sbjct: 8128 RCEIQNDVGSTSCQATLFVKEPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKE 8187

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-- 1382
               I   +  + S  +  ASL +   E  D+G+Y     N  G     M + + + P+  
Sbjct: 8188 GSEIHPSERYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVKEIPTII 8247

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSI 1440
                P  L  DS++   C    + TG S   + +  + +EI ++   S   I  T    +
Sbjct: 8248 KDLAPAELVKDSTAHLEC----QVTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEV 8303

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
                      ++    NEV    +  T +    +KE     PT  K L+N  T   +   
Sbjct: 8304 HKCGAADVGEYQCTVANEVGSCTSKATLK----LKEP----PTFTKKLENTDTVLGKMAV 8355

Query: 1501 LTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXX-XXXXXXXYKCIAFNDH 1556
              C+  G P   V W +D   +      + T+EN                 Y C   N+ 
Sbjct: 8356 FQCVVEGSPTLSVQWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVNEA 8415

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G+ + S  + +Q+ P IT   E IK    VGD   +   + G P  +V W K G +L++ 
Sbjct: 8416 GQTKCSATLTVQEPPQITEKPEVIKVT--VGDPVSLDCKVTGSPALKVKWMKEGKELQSI 8473

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            +++ +  +   S ++I+  +R    +Y +E +N    +S +V L V
Sbjct: 8474 RQHKLVFENNISSLKIQAAEREDEGEYILEVANHISRTSCKVRLVV 8519



 Score =  213 bits (521), Expect = 3e-53
 Identities = 214/862 (24%), Positives = 368/862 (42%), Gaps = 62/862 (7%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP  +E+++ K       V+F  +V G P P+  WF+   +++ ++    ++ +DNV  L
Sbjct: 1807 APRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCEL 1866

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            VIR+V  ED+ +    A N AG ASS   L+V+                        A  
Sbjct: 1867 VIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAKA 1926

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                         A   ++ + +  EC   + P   + WL    EI   +   +  +  +
Sbjct: 1927 AVSFTQHLED---ATANEKDTMVTFECE-TSEPFIKVKWLKNNTEIFSGDKYRMHSDRKV 1982

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            H + SVL I +++   +  YT V  + E   +    L ++    E  + +E ++      
Sbjct: 1983 H-FLSVL-IIDLR--DDAEYTCVLADDESVRT-SARLTVEGAALELIKHMENIEVPETYA 2037

Query: 749  GE-SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            GE  V LS + V          K   P       S    H++++   +K +D+G YT   
Sbjct: 2038 GEFEVELSREDVEGS--WFFGDKELSPSSKHIMSSRRGRHTLSVKDVRK-EDQGKYTFVC 2094

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
                G   TSA + ++        P   +    +++V E    +L  R ++  V   TW 
Sbjct: 2095 ----GDLRTSASLKMK------LRPVTLMLPLTDLSVCEGDIAQLEVRFSQENVEG-TWM 2143

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++ + ISPS+ +    D +  +L++ NV +E D+  Y  V   +   S+ G    + V+ 
Sbjct: 2144 KSGQAISPSDRVHIVIDKQVHKLLLENVSTE-DAASYSFVVP-AQDISTAGK---LSVQT 2198

Query: 928  VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            +  V  L K   T EG   +LE + S     S KWYHN K+++  D  + + +G      
Sbjct: 2199 IDIVVPL-KDLSTVEGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLV 2257

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D G  K +V   +TS  L V++     ++ ++D    E       VE++    
Sbjct: 2258 FSRTHASDQGQYKLVVGKVDTSCTLTVEKV--HIVKHMEDRVCSESQKVTFRVEVSHPGI 2315

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            D VW    +++KP   KY  E +  +  L I +T   +EG+Y     +++ +A +TV   
Sbjct: 2316 DPVWTVRNQLLKPGA-KYKMESKDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTV--- 2371

Query: 1106 PPEIITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
                ITR LQ+  V +   A  E E+   +A  RW K+G  + FS ++   + G  ++L 
Sbjct: 2372 SGGAITRPLQDVTVAESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLT 2431

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
            I      D GEYS +V NSK TA L VE   I  TLR      V    DA  T+E+   +
Sbjct: 2432 ITITRPQDVGEYSYQVANSKTTANLRVEAVKIKKTLRNQ---TVTETQDAVFTLELTHAD 2488

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
                 W K    ++ ++K+ + SD   ++L IR C   D+  Y+  L    +  +L VE 
Sbjct: 2489 VKGSQWIKNGVELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVET 2548

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVD----YQAFPQPND---EWIVNSKIIKKCKHTKP 1336
            ++             IK+  DVT L+D    ++     +D   +W+     +K     K 
Sbjct: 2549 IKI------------IKKTKDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKI 2596

Query: 1337 SIDSKSASLTIKKVENTDAGIY 1358
              + ++  L ++ V +++AG Y
Sbjct: 2597 LRERRAHKLILQNVNSSNAGEY 2618



 Score =  208 bits (509), Expect = 1e-51
 Identities = 194/775 (25%), Positives = 326/775 (42%), Gaps = 41/775 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F +K +      GS++ L C L       ++W+    E+   E+I +  ES+     
Sbjct: 7774 PPSFVQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITYESNT---- 7829

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            ++L IT+V++   G Y+  A N+ G  +   +L +K    EP ++ +  KS+ V QG+  
Sbjct: 7830 ALLHITDVQRNHAGKYSCQAQNQAGSQTCSALLTVK----EPAEITDEAKSISVTQGDPA 7885

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810
             L A+  G       W K  K + +        T S ++LK  K    D G YT +  N 
Sbjct: 7886 TLEARFSGTKPLRAMWIKAGKELISGQRYKVLSTDSSSVLKINKTDKSDGGEYTFRVSND 7945

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G +     +T+ +       PP F  + ++    +     L   V+ +   ++ WY+++
Sbjct: 7946 VGQSSCEVTLTILD----QIIPPSFTRKLKQTEGIKASFAHLECLVSGSLPITVHWYKDD 8001

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            + I         F      L I+++DS+ D G Y C+A N AG     A +   V++   
Sbjct: 8002 KEIQADHKHKCTFFENVAFLEISDLDSK-DGGSYTCIAKNKAGAVQCSAILL--VKEPPC 8058

Query: 931  VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            +    +S     G  V      S T  ++ KW+ N+KEI       +I++          
Sbjct: 8059 ILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSLALFF 8118

Query: 989  XXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDV-AILEVEIN-S 1042
                D G  +C +++   ST     L VKE  P+F R      V       + E ++  +
Sbjct: 8119 AKSSDSGEYRCEIQNDVGSTSCQATLFVKEP-PKFTRTPARVSVTRLGQNKVFECQVTGT 8177

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTA 1098
               DV W ++G  I P + +Y       +  L +  T   D G Y C  R+E    SC+ 
Sbjct: 8178 PEIDVYWFKEGSEIHPSE-RYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSM 8236

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS-NHIQLTI 1156
            E+ V E+P  II  L   ++ K + A  E ++T      V W++D  EI+ S  H    I
Sbjct: 8237 ELKVKEIPT-IIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQI 8295

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS--KCT--AILTVEEPSINFTLRLPEFILVPANT 1212
            +G    L+++ C   D GEY C V N    CT  A L ++EP   FT +L     V    
Sbjct: 8296 NGTLG-LEVHKCGAADVGEYQCTVANEVGSCTSKATLKLKEPP-TFTKKLENTDTVLGKM 8353

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              +  V     TL V W K  + I +  K     +     L I  C      +Y+C +++
Sbjct: 8354 AVFQCVVEGSPTLSVQWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVN 8413

Query: 1273 AKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
                TK    + V+ PP+I +     ++  G  V+L       P    +W+   K ++  
Sbjct: 8414 EAGQTKCSATLTVQEPPQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSI 8473

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
            +  K   ++  +SL I+  E  D G Y L + N+      ++ + +L +    GK
Sbjct: 8474 RQHKLVFENNISSLKIQAAEREDEGEYILEVANHISRTSCKVRLVVLVEWQKDGK 8528



 Score =  198 bits (484), Expect = 1e-48
 Identities = 204/826 (24%), Positives = 341/826 (41%), Gaps = 86/826 (10%)

Query: 500   KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
             K T +E    P+F  KL P+    G +++ EC + G    ++TW +    I+   ++ + 
Sbjct: 9482  KLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNIS 9541

Query: 560   YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
               D N   L I +    D G + C A N  G  S +             S++TV      
Sbjct: 9542  CVD-NTPHLTILKADKGDTGKYFCHAMNDVGKVSCS-------------SDVTVKERKN- 9586

Query: 620   XXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                          PP F+KKP     D EG  + +E R+       ++W  +  EI   +
Sbjct: 9587  -------------PPVFTKKPSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSD 9633

Query: 679   NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
                ++ +S++ + C  +K ++V     G YT  A N  G AS    + I   +K PP   
Sbjct: 9634  KYDISFKSNVAVLC--IKSSHVT--DSGRYTCQASNEAGRASCCTTVGISEAKK-PPVFD 9688

Query: 739   EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKK 796
              PLK + V +GE + L   V G+    I W K+ K + +        T     L+  P  
Sbjct: 9689  VPLKPLTVDEGEKMSLKCHVCGSAPLIIQWMKDRKELTSGGNTKISFTDGTACLEISPAS 9748

Query: 797   VKDEGVYTLKAENSEGIAETSAVITVEE-------PTEENA--------EPPLFINRFQE 841
              KD G Y  KA N  G   + A + V +       P E  A        +   FI   + 
Sbjct: 9749  RKDAGDYLCKATNDAGSEFSKAKVAVRQKPGAALAPAEAPAVAAPVKRQDNLFFIEEPKA 9808

Query: 842   ITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEID 900
             + V EK T   + +V  +P+PS+ W +     ++    I+ +  G+  +L I  V +  D
Sbjct: 9809  VRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGGRISVDQKGQEAKLEIREV-TRSD 9867

Query: 901   SGDYKCVASNSAGKSSHGARVTIDVEKVTFV----------KHLQKSYETEEGKTVILEC 950
             SG Y+C+ASN  G+    + + ++ +K + V          K   K    +E K + +  
Sbjct: 9868  SGQYRCIASNKHGEIECSSDLLVEEKKESAVLEGDLRAKLKKTPSKQKSPKEEKDIDI-V 9926

Query: 951   QTSHTVSTKWYHNKKEISGM-DHREIIQ------------EGRXXXXXXXXXXXXDVGVI 997
             +    V  K Y     + G+ D+R ++Q             GR            D+  +
Sbjct: 9927  ELLRNVDPKEYEKYARMYGITDYRGMLQAIEQLKKEKAMESGRPELERAERESDEDMARL 9986

Query: 998   KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
                ++ +   T  V   T+   I     F  KE +    EV IN     + W +  + + 
Sbjct: 9987  VADLQKRMERTEPV---TVLSDISDQSVFTGKEAEFQC-EVTINYPEITLSWYKGTQKLD 10042

Query: 1058  PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
                +KYD    G    L IR     D+G Y  +      +A++TV+E   E+   LQ+  
Sbjct: 10043 -SSDKYDISISGDRHLLRIRRCQTSDQGNYRVVCGPHISSAKLTVMEA--EVEKHLQDTS 10099

Query: 1118  VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
               +G   T   +L+  +   +WFK+G  ++        +  K QKL I D   +D G Y+
Sbjct: 10100 GKEGQSCTLSCQLSIPNVQAQWFKNGKRLEMKGKFTSEVKHKIQKLLISDLKPEDQGRYT 10159

Query: 1178  CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237
             C+  + + +A L VE   I+FT R+   I V     A    E+  +   V+WYK    ++
Sbjct: 10160 CQYQSLESSADLWVEAEQIHFTKRIHN-IEVNERQSATFECEVSFDNAIVSWYKDTWELK 10218

Query: 1238  DTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKVE 1282
             ++ K+   S+ ++  ++IR  T ED++ E   V L A+   +  VE
Sbjct: 10219 ESPKYNFTSEGRRHFMVIRNVTIEDEEIELAMVPLAARVLIEETVE 10264



 Score =  197 bits (480), Expect = 3e-48
 Identities = 220/1022 (21%), Positives = 405/1022 (39%), Gaps = 58/1022 (5%)

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQ 736
            + + V   S   M  S+++  +V +   G     AV  EG A      L I+    +   
Sbjct: 6594 QRLQVTSASRKQMLSSMVETASVAESAAG---FSAVKAEGAALRTESKLTIECAAAQQQV 6650

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
            V++  K+  +R+  +  L        + ++   K    V+++  KS  +     ++ P  
Sbjct: 6651 VVQETKAAAIRESTTSQLRVSTEAAFQQSVQVVKEE--VRSVLVKSREEDVGAAVV-PSA 6707

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
                 ++  +  +   + E   V+  E       E P  +   ++I+V E     L   +
Sbjct: 6708 TLPTTIHEEETVDISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTI 6767

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            T      + W  N +++ P +    + + +   LVI+ V  E+  G+Y C A N AGK++
Sbjct: 6768 TH--AAKVNWLFNGQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTT 6825

Query: 917  HGARVTIDVEKVTFVKHLQ-KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHR 973
              +R+T+ V +V  V  L+  + E   G +    C+ S    V+ +WY +  EI   +  
Sbjct: 6826 TSSRLTV-VPRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKY 6884

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVK-----DQETSTMLVVKETIPEFIRKLQDFEV 1028
             I+                D G   C V      D   ++++V +   P F+ K +   +
Sbjct: 6885 RIVSSSTSSALELVSPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTL 6944

Query: 1029 KEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
                 A+ +  +  S   DVVW +D   I   + KY  +   +   L+I++  +  +G Y
Sbjct: 6945 FVGKEAVFQCSLTGSSPMDVVWHKDNLAIS-SEGKYVMKSDKNKYSLHIQSLELAHQGVY 7003

Query: 1088 SCILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKD 1142
             C   +   TA    E+ V++  P  +           +    E ++ +   + + W +D
Sbjct: 7004 LCKASNSVGTATFSTELWVID-KPSFVKPFDQASAAVNDPVRLECQVNEDTGVTIIWTRD 7062

Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSIN 1197
            G ++  S   +L+ + K   ++I    L D+G+Y C    E G+S C A++ V+E PSI 
Sbjct: 7063 GKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSIR 7122

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256
              L+  E +       AYL  EI      ++TW K +  I   +K+ +IS      L I 
Sbjct: 7123 KELQTVEAL---KGGPAYLEYEIAGTAPFEITWSKNRKPITSDKKYNIISQQSLSRLEIL 7179

Query: 1257 KCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
                 D  +Y  V+ +   K +TK   ++ E PP             G+ V L    +  
Sbjct: 7180 TFESADVGDYQMVVSNEVGKVSTKAVAKLKE-PPSFTKRVDSVTAVLGTTVKLQGTVKGS 7238

Query: 1315 PQPNDEWIVNSKIIKKCKHT-KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
                 +W+ +S+ ++    +   + D+  A L+I  V  +  G Y  + EN  G    E 
Sbjct: 7239 SPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQKSEA 7298

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQE-IDTTEWIS 1429
             +T+  +P+   +P      ++SI++   E    E+T + +    V  +++  + T    
Sbjct: 7299 TLTV-QEPARVVEP------AASISVTAGESATLESTISGSPELKVKWFKDGKEMTSGRK 7351

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
             K   K  T+   + +        Y +   +     E T    V+  T    PT  KPL+
Sbjct: 7352 CKMTVKDNTATMKILSAEKSDSAEYIMQVSNKVGKDECTCSLTVLDRT--MPPTFTKPLR 7409

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXX 1545
             +      D  L C   G     + W++D  ++    K      ++              
Sbjct: 7410 RVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKDHSATLQIAGLEKADS 7469

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              YKC A N  G  ETS  + +++ P  T+  +   Q    G      A   G  P  V 
Sbjct: 7470 GVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDG--QDVIPGSTVSFRAAFTGTAPLTVK 7527

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W+K   ++ +   Y I     +S + ++ +K S S++Y  + SN AG       L V + 
Sbjct: 7528 WFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVKEP 7587

Query: 1666 PS 1667
            P+
Sbjct: 7588 PT 7589



 Score =  195 bits (476), Expect = 1e-47
 Identities = 212/983 (21%), Positives = 390/983 (39%), Gaps = 57/983 (5%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789
            EPP   +  + M   +G+ V L  ++ G     +TW K+ KP+   +     S+G + ++
Sbjct: 8734 EPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTL 8793

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
             I+  +   D G Y  K  NS G      ++ + EP       P F+ +   +TV     
Sbjct: 8794 HIIGLEST-DIGQYECKVSNSVGSDTCQTLVKLREP-------PSFVKKLSNMTVVLGQE 8845

Query: 850  IKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            + L A V  +   +++W ++ + I+   +     F+   + L +   D+   +G Y C  
Sbjct: 8846 VTLQATVKGSEPITVSWVQDKDHILRDGDNRRITFENNTVTLKVFKADAST-AGRYTCHL 8904

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKE 966
            +N AG S   A + + +E    V     +     G    LE +   T  + TKW+ +  E
Sbjct: 8905 TNDAGTSECFANLNV-LEPAKIVDK-PDALSVTAGDIAALEVKVCGTPELVTKWFKDGIE 8962

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVG-----VIKCIVKDQETSTMLVVKETIP-EFI 1020
            ++  +  +I                 D G     ++  + KD     + V+ + IP  F 
Sbjct: 8963 LASGNKYKISFSRMISCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFS 9022

Query: 1021 RKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
            RKL+D          +E +++ S    + W  DGE I+   N Y+     +   L +   
Sbjct: 9023 RKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPN-YEISFSNNSCILRVPTL 9081

Query: 1080 SVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA- 1135
             + D G Y C   +E+ T+E      V+ PP  +   Q+ +   G+  TF   + KG A 
Sbjct: 9082 KLSDSGLYKCKAVNEAGTSETAATMDVKEPPSFVVPPQSLEALPGSNVTFSA-MVKGSAP 9140

Query: 1136 -LVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEV----GNSKCTAIL 1189
              ++WF+   E++       ++    Q  L++++ D   AGEY+C++    G       L
Sbjct: 9141 LKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAGKESWPVNL 9200

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
            +++EP+  F+ +L +  +                 + V WYK    +  + K+  I+  +
Sbjct: 9201 SIKEPAA-FSKKLKDVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYN-ITTTE 9258

Query: 1250 KRTLIIRKCTEDDQC--EYTC-VLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
               ++    T+D +   +Y C V  DA + T +  V ++E PP  V+      +  G  V
Sbjct: 9259 SSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSILE-PPYFVESLEPMEVTAGDAV 9317

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
             L       P+    W      ++     +       A L + K    D G Y  + EN 
Sbjct: 9318 CLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENR 9377

Query: 1366 CGHADVEMNVTILDKPSPPGKPN-ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEID 1423
             G       + +L+  +PP  P  I  +  +       E    G+S I + ++ + + + 
Sbjct: 9378 IGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGEPLK 9437

Query: 1424 TTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
                 S+     T    I+  +   S  +   A N V       T+   K+  +     P
Sbjct: 9438 AGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSV-----GSTSCRAKLTLQEPRYPP 9492

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXX 1538
              ++ L        + IEL C   G    KVTW +D K +++      +  +N       
Sbjct: 9493 VFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTIL 9552

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVI 1596
                     Y C A ND G+V  S  V ++++  P +         +   G    +   +
Sbjct: 9553 KADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRV 9612

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
             G  P  V WYK   ++ +  +Y+I+ K   +V+ IK    + S +YT +ASN AG +S 
Sbjct: 9613 SGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAGRASC 9672

Query: 1657 EVTLKVYDKPSKPEGPVIMREIS 1679
              T+ + +    P   V ++ ++
Sbjct: 9673 CTTVGISEAKKPPVFDVPLKPLT 9695



 Score =  194 bits (473), Expect = 2e-47
 Identities = 230/1054 (21%), Positives = 403/1054 (38%), Gaps = 63/1054 (5%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            VDE S   L   +    +  + WLF G+ + P +    + E D +    + K+  VK+  
Sbjct: 6755 VDEDSKATLSTTITHAAK--VNWLFNGQLVKPGKEFRCSKEKDTYTLV-ISKV--VKEMH 6809

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            +G Y   A N  G+ +    L +    + PP     + ++ +  G S     +V   P  
Sbjct: 6810 QGEYVCEAENEAGKTTTSSRLTVV--PRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDV 6867

Query: 765  TITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
               W K+   +K        S   + ++ ++ P K  D G Y+ K  N  G+   +A + 
Sbjct: 6868 NFRWYKSGVEIKQSEKYRIVSSSTSSALELVSPVKA-DSGEYSCKVSNPHGVDTCAASLI 6926

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V E       PP+F+++ + +T+           +T +    + W+++N  IS       
Sbjct: 6927 VTE-----LYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVM 6981

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
              D     L I +++     G Y C ASNS G ++    + + ++K +FVK   ++    
Sbjct: 6982 KSDKNKYSLHIQSLEL-AHQGVYLCKASNSVGTATFSTELWV-IDKPSFVKPFDQA-SAA 7038

Query: 942  EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
                V LECQ +    V+  W  + K++      ++  E +            D G   C
Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVC 7098

Query: 1000 IVKDQ--ETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEI-NSETADVVWERDGEI 1055
               ++   +S   VV    P  IRK LQ  E  +   A LE EI  +   ++ W ++ + 
Sbjct: 7099 TATNEAGSSSCEAVVMVQEPPSIRKELQTVEALKGGPAYLEYEIAGTAPFEITWSKNRKP 7158

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITR 1112
            I   K KY+   +  + +L I      D G+Y  ++ +E     T  V  ++ PP    R
Sbjct: 7159 ITSDK-KYNIISQQSLSRLEILTFESADVGDYQMVVSNEVGKVSTKAVAKLKEPPSFTKR 7217

Query: 1113 LQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCD 1169
            + +     G     +    KG +   V+W KD   ++  +  I LT D     L I    
Sbjct: 7218 VDSVTAVLGTTVKLQ-GTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVA 7276

Query: 1170 LDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DET 1224
            +   G+Y C    E G  K  A LTV+EP+    +     I V A   A L   I     
Sbjct: 7277 ISHGGKYVCQAENEAGQQKSEATLTVQEPA--RVVEPAASISVTAGESATLESTISGSPE 7334

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLK 1280
            L V W+K    +    K  +       T+ I    + D  EY   + +     + T  L 
Sbjct: 7335 LKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKSDSAEYIMQVSNKVGKDECTCSLT 7394

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V     PP      R      G+D +L             W  +   I      +     
Sbjct: 7395 VLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKD 7454

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
             SA+L I  +E  D+G+YK R  N+ G  +    + + + P+   KP+  ++   S    
Sbjct: 7455 HSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDGQDVIPGSTVSF 7514

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
                  T   T+ ++  + + +    +   K+ T +   +Q +K + S R+     N+  
Sbjct: 7515 RAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSARYACQVSNDAG 7574

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDG 1519
              D +        +KE     PT  + L+  T     +   L C   G P     W++D 
Sbjct: 7575 KVDCTALL----FVKE----PPTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKDE 7626

Query: 1520 KKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VI 1573
             ++    K   A  +                 Y C+A ++ G       V ++  P  V 
Sbjct: 7627 MEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPSFVR 7686

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
            ++ ++D+ +    G E ++   + G  P  V   KNG  + NDK + IT K++   +++ 
Sbjct: 7687 SLESKDVVK----GSELMLEGQVSGSAPFTVTLCKNGKAIRNDKRHRITVKDELIALQVL 7742

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             ++      Y     N  G  S +  + + D PS
Sbjct: 7743 AVEAGDVGLYQCTVENQVGRVSCDCHVTLKDPPS 7776



 Score =  192 bits (467), Expect = 1e-46
 Identities = 222/1003 (22%), Positives = 390/1003 (38%), Gaps = 95/1003 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V E    +LEC  VA  E +  W+ +G+ +   EN+   ++  +      L IT  +   
Sbjct: 2385 VAESQTAVLECE-VANAEAEGRWMKEGQPVDFSENVVSEVKGAVRR----LTITITRPQD 2439

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y+    N +  A+L +         E  ++ + L++  V + +  + + ++      
Sbjct: 2440 VGEYSYQVANSKTTANLRV---------EAVKIKKTLRNQTVTETQDAVFTLELTHADVK 2490

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
               W KN   +++       SDG   S+ I +    +DE VY+ K      + + SA   
Sbjct: 2491 GSQWIKNGVELQSSDKYEISSDGMVQSLKI-RNCNTQDESVYSFK------LGKLSANAR 2543

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            +      N E    I + +++T    GT      ++ + VP + W      + PS+    
Sbjct: 2544 L------NVETIKIIKKTKDVTTLMDGTASFEMSLSHDDVP-VKWMFKGAELKPSDRCKI 2596

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
              +    +L++ NV+S  ++G+Y  V  +           T+ VE +  VK + K     
Sbjct: 2597 LRERRAHKLILQNVNSS-NAGEYTAVVGHLQ------CSATLTVEALQIVKPM-KDASVA 2648

Query: 942  EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            E +    EC+ SH  V + W  +  EI   +   I+ +G+            D      I
Sbjct: 2649 ETQAATFECEVSHFNVPSTWLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFI 2708

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
              +   S  L V   +      L+D   +E+D    EV +N E     W ++G  +K   
Sbjct: 2709 CGNDRVSATLTVSPVL--ITSMLKDLNAQERDTITFEVTVNHEGITYKWLKNGVEVK-SS 2765

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
            ++     R     L IRN    D GEY  +    + +A + V     E   ++++ K+ +
Sbjct: 2766 DRCQVRSRQLTHTLTIRNVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKIIE 2825

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCE 1179
              KA FE E+++ +  V W KDG E+  S    +T   K   +L I    + DAGEYS  
Sbjct: 2826 KKKAIFECEVSEPNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVV 2885

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
             G+S   A L VE   I         I V     A +  E+ ++ ++  W K  + +   
Sbjct: 2886 AGSSVSKAQLVVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNGAELSLE 2945

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
            E+F+ +   K   + I +    D  EYT +    +S+  L+V + E PP+I+ +     +
Sbjct: 2946 ERFSYVVIRKVHRITISETFRSDAGEYTFIAGKNRSSVNLRVNIPE-PPQILRHMEPQSV 3004

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            + G      V+    PQP   W  NS+++      K   ++   SL + +V   DA +Y 
Sbjct: 3005 EVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYS 3064

Query: 1360 LRLENNCGHAD--VEMNVTILDKPSP----PGKPNILEIDSSSINICWDEPEN-----TG 1408
               +N+ G A     +NV + +  SP       P ++    SS +    EP        G
Sbjct: 3065 CEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHG 3124

Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
            +   I +  + +EI  +E+  +     + Q  I  +       +   A N    +  S T
Sbjct: 3125 DDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSAT 3184

Query: 1468 ---------------------TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
                                 T    + K    Q PT  +P+++ T              
Sbjct: 3185 LTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPIRSCTVAHGAVARFHACVS 3244

Query: 1507 GVPQPKVTWYRDGKKLK-TAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            G+P+P+V+W+ + + ++ T    +      N                Y C A N  GE  
Sbjct: 3245 GMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSAGEAA 3304

Query: 1561 TSC---VVGIQQKPVITIS-------NEDIKQK-HKVGDEWLV 1592
             S    +  +QQ+ V  +         +DIK+  H  G E LV
Sbjct: 3305 CSATLTITKVQQEEVTVVKEQTQIQIQQDIKEPFHGSGSEELV 3347



 Score =  186 bits (453), Expect = 6e-45
 Identities = 181/781 (23%), Positives = 317/781 (40%), Gaps = 50/781 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            IPP+FS+K K  +   G    +EC++   P   I+W   GEEI    N  ++  ++    
Sbjct: 9017 IPPSFSRKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNS--- 9073

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            C +L++  +K    G Y   AVN  G +     + +    KEPP  + P +S+    G +
Sbjct: 9074 C-ILRVPTLKLSDSGLYKCKAVNEAGTSETAATMDV----KEPPSFVVPPQSLEALPGSN 9128

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLKAE 808
            V  SA V G+    + W +  K ++   T S   T +  ++      D    G YT +  
Sbjct: 9129 VTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQII 9188

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G       ++++EP         F  + ++++V++   + L    T  P  ++ WY+
Sbjct: 9189 NDAGKESWPVNLSIKEPA-------AFSKKLKDVSVEKGKPLTLECTYTGTPKITVNWYK 9241

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            + + +  S          +  L   + D +  +G Y C  SN AG+ +  A V+I +E  
Sbjct: 9242 DGQQVFASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSI-LEPP 9300

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             FV+ L+   E   G  V L+C+ + T  +   W+    ++       +           
Sbjct: 9301 YFVESLE-PMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLKL 9359

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040
                  D+G   C  +++     +S  L V E  T P F +K+   +  E      E  I
Sbjct: 9360 SKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRI 9419

Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
              S   +V W RDGE +K    ++      +   L I    +   GEY+C+  +     S
Sbjct: 9420 AGSSPIEVSWLRDGEPLK-AGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTS 9478

Query: 1096 CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152
            C A++T+ E   PP    +L  Q+V  G+    E  +T    + V W KD  +I+   + 
Sbjct: 9479 CRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNY 9538

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE---PSINFTLRLPEF 1205
             ++       L I   D  D G+Y C    +VG   C++ +TV+E   P + FT +  E 
Sbjct: 9539 NISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPPV-FTKKPSEH 9597

Query: 1206 ILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            +         +   +   + + V+WYK+ + I  ++K+ +        L I+     D  
Sbjct: 9598 MEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSG 9657

Query: 1265 EYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
             YTC   +    A   T + +   + PP      +   +  G  ++L            +
Sbjct: 9658 RYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAPLIIQ 9717

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W+ + K +    +TK S    +A L I      DAG Y  +  N+ G    +  V +  K
Sbjct: 9718 WMKDRKELTSGGNTKISFTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVAVRQK 9777

Query: 1381 P 1381
            P
Sbjct: 9778 P 9778



 Score =  184 bits (448), Expect = 2e-44
 Identities = 243/1164 (20%), Positives = 451/1164 (38%), Gaps = 87/1164 (7%)

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            VA L ++    +D G +TC A+N AG  S +T L ++  L      + +           
Sbjct: 8674 VAVLELQSAGFDDDGVYTCEAQNDAGSVSCSTTLSIKGQLLIDFLWLILIILGLDSEAAV 8733

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
                    PP+F+K P+     +G D+ L C L       + W    + ++      +  
Sbjct: 8734 E-------PPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLS 8786

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
            E         L I  ++    G Y     N  G  +   ++K++    EPP  ++ L +M
Sbjct: 8787 EGSS----VTLHIIGLESTDIGQYECKVSNSVGSDTCQTLVKLR----EPPSFVKKLSNM 8838

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI------LKPKKV- 797
             V  G+ V L A V G+   T++W ++   +       DGD   IT       LK  K  
Sbjct: 8839 TVVLGQEVTLQATVKGSEPITVSWVQDKDHILR-----DGDNRRITFENNTVTLKVFKAD 8893

Query: 798  -KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
                G YT    N  G +E  A + V EP +        +++   ++V       L  +V
Sbjct: 8894 ASTAGRYTCHLTNDAGTSECFANLNVLEPAK-------IVDKPDALSVTAGDIAALEVKV 8946

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
               P     W+++   ++       +F      L + + + ++DSG+Y     N  GK  
Sbjct: 8947 CGTPELVTKWFKDGIELASGNKYKISFSRMISCLNVLSTE-KLDSGEYTFEIMNEVGKDL 9005

Query: 917  HGARVTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMD 971
                +T+ ++K+   +F + L K   T  GK   +EC+ S +   +  W+H+ +EI    
Sbjct: 9006 SKINLTV-LDKIIPPSFSRKL-KDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGP 9063

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE 1027
            + EI                 D G+ KC   ++    ET+  + VKE  P F+   Q  E
Sbjct: 9064 NYEISFSNNSCILRVPTLKLSDSGLYKCKAVNEAGTSETAATMDVKEP-PSFVVPPQSLE 9122

Query: 1028 -VKEKDVAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEG 1085
             +   +V    +   S    + W R  + ++P +   +       +  L + N      G
Sbjct: 9123 ALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVM-LELFNVDRSHAG 9181

Query: 1086 EYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWF 1140
            EY+C I+ D   ES    +++ E P     +L++  V KG   T E   T    + V W+
Sbjct: 9182 EYTCQIINDAGKESWPVNLSIKE-PAAFSKKLKDVSVEKGKPLTLECTYTGTPKITVNWY 9240

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCD-LDDAGEYSCEVGNSK----CTAILTVEEPS 1195
            KDG ++  S    +T       L+    D  + AG+Y CEV N      C A +++ EP 
Sbjct: 9241 KDGQQVFASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSILEPP 9300

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
              + +   E + V A     L  ++     + V+W+K    +  +    L        L 
Sbjct: 9301 --YFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLK 9358

Query: 1255 IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            + K T+ D  EY+C   +      S+ +L V   + PP         +   G  +     
Sbjct: 9359 LSKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECR 9418

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
                      W+ + + +K         D  +A L I++ E   +G Y     N+ G   
Sbjct: 9419 IAGSSPIEVSWLRDGEPLKAGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTS 9478

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWI 1428
                +T+ +   PP     L     ++    + E   TG++ I + +  ++++I +    
Sbjct: 9479 CRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNY 9538

Query: 1429 SVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEK 1486
            ++  +  T   +I       + ++  +A+N+V  +S +S+ T     +KE K      +K
Sbjct: 9539 NISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVT-----VKERKNPPVFTKK 9593

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXX 1542
            P +++       +++     G     V+WY++  ++ ++     +   N           
Sbjct: 9594 PSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHV 9653

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPP 1601
                 Y C A N+ G       VGI +     + +  +K      G++  +   + G  P
Sbjct: 9654 TDSGRYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAP 9713

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
              + W K+  +L +     I+  + T+ + I    R  +  Y  +A+N AG+   +  + 
Sbjct: 9714 LIIQWMKDRKELTSGGNTKISFTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVA 9773

Query: 1662 VYDKP----SKPEGPVIMREISRE 1681
            V  KP    +  E P +   + R+
Sbjct: 9774 VRQKPGAALAPAEAPAVAAPVKRQ 9797



 Score =  183 bits (446), Expect = 4e-44
 Identities = 237/1068 (22%), Positives = 425/1068 (39%), Gaps = 86/1068 (8%)

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            EG+  +LE ++ A     + W    +++ P + I    +         L  +      +G
Sbjct: 2212 EGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQR----LVFSRTHASDQG 2267

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
             Y +V    +   +L +         E   +++ ++  +  + + V    +V  +P    
Sbjct: 2268 QYKLVVGKVDTSCTLTV---------EKVHIVKHMEDRVCSESQKVTFRVEV-SHPGIDP 2317

Query: 767  TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             W   N   KP      +S    HS+TIL   K  +EG Y   A    G   +SA++TV 
Sbjct: 2318 VWTVRNQLLKPGAKYKMESKDKVHSLTILDTMK-DEEGQYMFHA----GEQTSSAMLTVS 2372

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                     PL     Q++TV E  T  L   V  N      W +  + +  SE +    
Sbjct: 2373 GGAITR---PL-----QDVTVAESQTAVLECEVA-NAEAEGRWMKEGQPVDFSENVVSEV 2423

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
             G    L IT +    D G+Y    +NS  K++   RV    E V   K L+    TE  
Sbjct: 2424 KGAVRRLTIT-ITRPQDVGEYSYQVANS--KTTANLRV----EAVKIKKTLRNQTVTETQ 2476

Query: 944  KTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
              V  LE   +    ++W  N  E+   D  EI  +G             D  V    + 
Sbjct: 2477 DAVFTLELTHADVKGSQWIKNGVELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLG 2536

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN- 1061
                +  L V ETI + I+K +D        A  E+ ++ +   V W   G  +KP    
Sbjct: 2537 KLSANARLNV-ETI-KIIKKTKDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRC 2594

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
            K   E+R H  KL ++N +  + GEY+ ++    C+A +TV  L  +I+  +++  V + 
Sbjct: 2595 KILRERRAH--KLILQNVNSSNAGEYTAVVGHLQCSATLTVEAL--QIVKPMKDASVAET 2650

Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              ATFE E++  +    W KDG EI+ S   ++ + GK  +LKI +   DD+ EY+   G
Sbjct: 2651 QAATFECEVSHFNVPSTWLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFICG 2710

Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
            N + +A LTV    I  T  L +      +T  +  V +  E +   W K    ++ +++
Sbjct: 2711 NDRVSATLTVSPVLI--TSMLKDLNAQERDTITF-EVTVNHEGITYKWLKNGVEVKSSDR 2767

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDYEREYRI 1299
              + S     TL IR     D  EY  V   A ++  L VE  V+EF  KI D +   + 
Sbjct: 2768 CQVRSRQLTHTLTIRNVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKIIEKK 2827

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIY 1358
            K   +  +     + P     W+ + + +   +    +   K    L I+ V  +DAG Y
Sbjct: 2828 KAIFECEV-----SEPNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEY 2882

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             +   ++   A + +    + + +PP + +I  ++     I ++  E+      +    E
Sbjct: 2883 SVVAGSSVSKAQLVVEGRDI-RIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNGAE 2941

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
                +   ++ ++ + +   S         Y F A   N   ++      E  ++++  +
Sbjct: 2942 LSLEERFSYVVIRKVHRITISETFRSDAGEYTFIA-GKNRSSVNLRVNIPEPPQILRHME 3000

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY---ENRXX 1534
             QS  V K L   + E +          GVPQP+V+WY++ + L    K  +    N+  
Sbjct: 3001 PQSVEVGK-LARFSVEVS----------GVPQPQVSWYKNSQMLSAGFKCKFLCEANQHS 3049

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y C A ND+G   ++  + ++   V++           +      T+
Sbjct: 3050 LLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISSTS 3109

Query: 1595 VIEGIP----------PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
              EG P            ++ W+    +++  + + ++  E +  + I  +      +Y+
Sbjct: 3110 AREGEPARFHCRVHGDDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGEYS 3169

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPL 1691
              A+N+ GT+S   TL + D  + PE G  + +     S+T   K P+
Sbjct: 3170 CVATNSGGTASCSATLTL-DGQTLPEAGAAVPQWHVSTSLTSIKKAPI 3216



 Score =  183 bits (445), Expect = 5e-44
 Identities = 233/1035 (22%), Positives = 424/1035 (40%), Gaps = 95/1035 (9%)

Query: 666  AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            +W F  +E+ P     ++     H     L + +V+K  +G YT V  +    ASL + L
Sbjct: 2052 SWFFGDKELSPSSKHIMSSRRGRH----TLSVKDVRKEDQGKYTFVCGDLRTSASLKMKL 2107

Query: 726  KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
            +       P  ++ PL  + V +G+   L  +         TW K+ + +    + SD  
Sbjct: 2108 R-------PVTLMLPLTDLSVCEGDIAQLEVR-FSQENVEGTWMKSGQAI----SPSD-R 2154

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
             H +   +  K+  E V T  A +   +     + T  + + +  +    +   ++++  
Sbjct: 2155 VHIVIDKQVHKLLLENVSTEDAASYSFVVPAQDISTAGKLSVQTID---IVVPLKDLSTV 2211

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            E     L A+++   + S+ WY N++ ++PS+ I     G    LV +   +  D G YK
Sbjct: 2212 EGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLVFSRTHAS-DQGQYK 2270

Query: 906  CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNK 964
             V     GK       T+ VEKV  VKH++    +E  K V    + SH  +   W    
Sbjct: 2271 LV----VGKVD--TSCTLTVEKVHIVKHMEDRVCSESQK-VTFRVEVSHPGIDPVWTVRN 2323

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
            + +      ++  + +            + G       +Q +S ML V        R LQ
Sbjct: 2324 QLLKPGAKYKMESKDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTVSG--GAITRPLQ 2381

Query: 1025 DFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
            D  V E   A+LE E+ +  A+  W ++G+ +   +N    E +G +R+L I  T   D 
Sbjct: 2382 DVTVAESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVS-EVKGAVRRLTITITRPQDV 2440

Query: 1085 GEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDG 1143
            GEYS  + +   TA + V  +  +I   L+NQ V +   A F +ELT  D    +W K+G
Sbjct: 2441 GEYSYQVANSKTTANLRVEAV--KIKKTLRNQTVTETQDAVFTLELTHADVKGSQWIKNG 2498

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203
             E+Q S+  +++ DG  Q LKI +C+  D   YS ++G     A L VE   I   ++  
Sbjct: 2499 VELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVETIKI---IKKT 2555

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
            + +    +  A   + +  + + V W  K + ++ +++  ++ + +   LI++     + 
Sbjct: 2556 KDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQNVNSSNA 2615

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             EYT V+   + +  L VE ++    IV   ++  +      T   +   F  P+  W+ 
Sbjct: 2616 GEYTAVVGHLQCSATLTVEALQ----IVKPMKDASVAETQAATFECEVSHFNVPS-TWLK 2670

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            +   I+  +  +  +  K   L I      D+  Y       CG+  V   +T+    SP
Sbjct: 2671 DGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTF----ICGNDRVSATLTV----SP 2722

Query: 1384 PGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQ 1441
                ++L ++++   +    E           ++    E+ +++   V++   T T +I+
Sbjct: 2723 VLITSMLKDLNAQERDTITFEVTVNHEGITYKWLKNGVEVKSSDRCQVRSRQLTHTLTIR 2782

Query: 1442 NLK--TNSSYRFRA-YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            N+       Y+F A  A    ++   +   E+ + IK+ KI    +EK       E +E 
Sbjct: 2783 NVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKI----IEKKKAIFECEVSE- 2837

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
                      P  +V W +DG++L  ++  Y                   + +  +D GE
Sbjct: 2838 ----------PNIQVMWMKDGQELDLSEERY------VTTAEKYVHRLMIQTVRMSDAGE 2881

Query: 1559 VETSCVVGIQ-QKPVITISNEDIKQKHKVGDEWLV----TAVIE---GIPPPEVIWYKNG 1610
               S V G    K  + +   DI+       +  V     A IE        E  W KNG
Sbjct: 2882 Y--SVVAGSSVSKAQLVVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNG 2939

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
             +L  ++ ++     K   I I E  RS + +YT      AG +   V L+V    + PE
Sbjct: 2940 AELSLEERFSYVVIRKVHRITISETFRSDAGEYTF----IAGKNRSSVNLRV----NIPE 2991

Query: 1671 GPVIMREISRESVTI 1685
             P I+R +  +SV +
Sbjct: 2992 PPQILRHMEPQSVEV 3006



 Score =  171 bits (416), Expect = 2e-40
 Identities = 232/1075 (21%), Positives = 420/1075 (39%), Gaps = 116/1075 (10%)

Query: 633  PPTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F++ P    V   G + + EC++   PE D+ W  +G EI P E   ++  + +   
Sbjct: 8149 PPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSL--- 8205

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L++   +    G Y   A N  G  S  + LK+K    E P +I+ L    + +  +
Sbjct: 8206 -ASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVK----EIPTIIKDLAPAELVKDST 8260

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK--VKDEGVYTLKAEN 809
              L  QV G     +TW ++ K +K+    S    +    L+  K    D G Y     N
Sbjct: 8261 AHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVAN 8320

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYR 868
              G   + A + ++EP       P F  + +   TV  K  +     V  +P  S+ W +
Sbjct: 8321 EVGSCTSKATLKLKEP-------PTFTKKLENTDTVLGKMAV-FQCVVEGSPTLSVQWQK 8372

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            ++  I     I + F+  N+ ++       + SG Y C   N AG++   A  T+ V++ 
Sbjct: 8373 DDNWILEDPKIERTFEN-NVAILKIPACEAVHSGKYSCQVVNEAGQTKCSA--TLTVQEP 8429

Query: 929  TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
              +    +  +   G  V L+C+   S  +  KW    KE+  +   +++ E        
Sbjct: 8430 PQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENNISSLKI 8489

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                  D G                  E I E    +     K + V ++E         
Sbjct: 8490 QAAEREDEG------------------EYILEVANHISRTSCKVRLVVLVE--------- 8522

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-V 1103
              W++DG+ I     K+   ++ +   + I      D G YSC L +   SC +  ++ V
Sbjct: 8523 --WQKDGKKIFSGV-KHKLIQQDNSVSVEIEQLEPSDAGRYSCKLTNAAGSCESSGSLQV 8579

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            + PP  ++  + Q      K  F+    KG     V+WFKD  E+         +DG   
Sbjct: 8580 KEPPSFVSPPEPQSAVPNAKVRFKGTF-KGTPPFTVQWFKDDRELMTGPTCFTGLDGLSC 8638

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA--NTDAYLTVE 1219
             L++Y  ++  +G YSC+V N+  +A       S N T+++    L  A  + D   T E
Sbjct: 8639 FLELYSVNISQSGVYSCQVSNAAGSA-----RCSANLTVKVAVLELQSAGFDDDGVYTCE 8693

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
              ++   V+     S+     K  L+ D     LII             + LD+++  + 
Sbjct: 8694 AQNDAGSVSCSTTLSI-----KGQLLIDFLWLILII-------------LGLDSEAAVE- 8734

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
                   PP            +G DV+L  +          W  + K + + +  K   +
Sbjct: 8735 -------PPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSE 8787

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSIN 1398
              S +L I  +E+TD G Y+ ++ N+ G    +  V + + PS   K  N+  +    + 
Sbjct: 8788 GSSVTLHIIGLESTDIGQYECKVSNSVGSDTCQTLVKLREPPSFVKKLSNMTVVLGQEVT 8847

Query: 1399 ICWDEPENTGNSTI-IYYVVEYQEI---DTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            +   +    G+  I + +V +   I        I+ +N T T   +     +++ R+  +
Sbjct: 8848 L---QATVKGSEPITVSWVQDKDHILRDGDNRRITFENNTVT-LKVFKADASTAGRYTCH 8903

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
              N+   +  SE      V++  KI    V+KP   ++    +   L     G P+    
Sbjct: 8904 LTND---AGTSECFANLNVLEPAKI----VDKP-DALSVTAGDIAALEVKVCGTPELVTK 8955

Query: 1515 WYRDGKKLKTA---KATYENRXX-XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            W++DG +L +    K ++                   Y     N+ G+  +   + +  K
Sbjct: 8956 WFKDGIELASGNKYKISFSRMISCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDK 9015

Query: 1571 PVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             +    +  +K  H V G    +   + G PP  + W+ +G ++++   Y I+    + +
Sbjct: 9016 IIPPSFSRKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCI 9075

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            +R+  LK S S  Y  +A N AGTS    T+ V + PS    P  +  +   +VT
Sbjct: 9076 LRVPTLKLSDSGLYKCKAVNEAGTSETAATMDVKEPPSFVVPPQSLEALPGSNVT 9130



 Score =  167 bits (405), Expect = 4e-39
 Identities = 211/1029 (20%), Positives = 409/1029 (39%), Gaps = 78/1029 (7%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V EG    LE R  +    +  W+  G+ I P + + + I+  +H     L + NV    
Sbjct: 2121 VCEGDIAQLEVRF-SQENVEGTWMKSGQAISPSDRVHIVIDKQVHK----LLLENVSTED 2175

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
              +Y+ V   ++   S    L ++T +     ++ PLK +   +G   +L A++      
Sbjct: 2176 AASYSFVVPAQD--ISTAGKLSVQTID-----IVVPLKDLSTVEGTKAVLEAKISAQDIS 2228

Query: 765  TITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            ++ W  N+K   P   + T + G    + +       D+G Y L      G  +TS  +T
Sbjct: 2229 SVKWYHNDKQVTPSDRIQTVAKGAKQRL-VFSRTHASDQGQYKLVV----GKVDTSCTLT 2283

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            VE+           +   ++    E   +     V+   +  + W   N+++ P      
Sbjct: 2284 VEKVH--------IVKHMEDRVCSESQKVTFRVEVSHPGIDPV-WTVRNQLLKPGAKYKM 2334

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
                +   L I +   + + G Y       AG+ +  A +T+    +T  + LQ      
Sbjct: 2335 ESKDKVHSLTILDTMKD-EEGQYMF----HAGEQTSSAMLTVSGGAIT--RPLQ-DVTVA 2386

Query: 942  EGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            E +T +LEC+ ++  +  +W    + +   ++     +G             DVG     
Sbjct: 2387 ESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLTITITRPQDVGEYSYQ 2446

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPK 1059
            V + +T+  L V+    +  + L++  V E   A+  +E+ +++     W ++G  ++  
Sbjct: 2447 VANSKTTANLRVEAV--KIKKTLRNQTVTETQDAVFTLELTHADVKGSQWIKNGVELQ-S 2503

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
             +KY+    G ++ L IRN +  DE  YS  L   S  A + V  +  +II + ++    
Sbjct: 2504 SDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVETI--KIIKKTKDVTTL 2561

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
                A+FE+ L+  D  V+W   G+E++ S+  ++  + +  KL + + +  +AGEY+  
Sbjct: 2562 MDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQNVNSSNAGEYTAV 2621

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
            VG+ +C+A LTVE   I   ++  +   V     A    E+    +  TW K    IE +
Sbjct: 2622 VGHLQCSATLTVEALQI---VKPMKDASVAETQAATFECEVSHFNVPSTWLKDGVEIEMS 2678

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
            EKF ++   K   L I   ++DD  EYT +  + + +  L V  V     + D   + R 
Sbjct: 2679 EKFRIVVQGKLHQLKIVNTSKDDSAEYTFICGNDRVSATLTVSPVLITSMLKDLNAQERD 2738

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
                +VT  V+++       +W+ N   +K     +      + +LTI+ V   D G Y+
Sbjct: 2739 TITFEVT--VNHEGITY---KWLKNGVEVKSSDRCQVRSRQLTHTLTIRNVHFGDGGEYQ 2793

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
                +    A++ +   +++         I+E   +       EP     +  + ++ + 
Sbjct: 2794 FVAGSAATSANLFVEARVIEFTRKIKDIKIIEKKKAIFECEVSEP-----NIQVMWMKDG 2848

Query: 1420 QEIDTTE--WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            QE+D +E  +++       +  IQ ++ + +  +   A + V  +         ++    
Sbjct: 2849 QELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSSVSKAQLVVEGRDIRIAPPA 2908

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533
            +     +EK    I  E NED             +  W ++G +L    + +        
Sbjct: 2909 ERDITVLEKHRATIEFEVNED-----------DVEGRWLKNGAELSLEERFSYVVIRKVH 2957

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y  IA  +   V     V I + P I    E   Q  +VG     +
Sbjct: 2958 RITISETFRSDAGEYTFIAGKNRSSVNLR--VNIPEPPQILRHME--PQSVEVGKLARFS 3013

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
              + G+P P+V WYKN   L    +     +     + + E+    ++ Y+ EA N  G 
Sbjct: 3014 VEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGA 3073

Query: 1654 SSVEVTLKV 1662
            +S   +L V
Sbjct: 3074 ASSTASLNV 3082



 Score =  149 bits (360), Expect = 1e-33
 Identities = 150/696 (21%), Positives = 289/696 (41%), Gaps = 32/696 (4%)

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            D+ V++   +     T +V +   P  +  L+D  V E   A L   I +  A V W  +
Sbjct: 6720 DISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTI-THAAKVNWLFN 6778

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVV-ELPP 1107
            G+++KP K     +++     +  +      +GEY C   +E+     ++ +TVV  +PP
Sbjct: 6779 GQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTTTSSRLTVVPRVPP 6838

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
                ++   ++N G+ A F  E++   D   RW+K G EI+ S   ++        L++ 
Sbjct: 6839 VFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALELV 6898

Query: 1167 DCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
                 D+GEYSC+V N      C A L V E      +  PE + +    +A     +  
Sbjct: 6899 SPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTLFVGKEAVFQCSLTG 6958

Query: 1223 ET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
             + +DV W+K    I    K+ + SD  K +L I+      Q  Y C   ++  T     
Sbjct: 6959 SSPMDVVWHKDNLAISSEGKYVMKSDKNKYSLHIQSLELAHQGVYLCKASNSVGTATFST 7018

Query: 1282 E--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
            E  V++ P  +  +++         V L             W  + K + +    K S +
Sbjct: 7019 ELWVIDKPSFVKPFDQASAAVN-DPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFE 7077

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
             K A + I K +  D+G Y     N  G +  E  V + + PS   +  +  +++     
Sbjct: 7078 DKVAVVEIPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSI--RKELQTVEALKGGP 7135

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
             + E E  G +       + ++  T++     NI  +Q S+  L+  +   F +  V + 
Sbjct: 7136 AYLEYEIAGTAPFEITWSKNRKPITSD--KKYNII-SQQSLSRLEILT---FESADVGDY 7189

Query: 1460 DISDASETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
             +  ++E  +   K + + K + P+  K + ++T      ++L     G     V W +D
Sbjct: 7190 QMVVSNEVGKVSTKAVAKLK-EPPSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKD 7248

Query: 1519 GKKLK----TAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVI 1573
             + L+    +   T++N                 Y C A N+ G+ ++   + +Q+   +
Sbjct: 7249 SEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQKSEATLTVQEPARV 7308

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
                  I      G+   + + I G P  +V W+K+G ++ + ++  +T K+ T+ ++I 
Sbjct: 7309 VEPAASISVT--AGESATLESTISGSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKIL 7366

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              ++S S++Y ++ SN  G      +L V D+   P
Sbjct: 7367 SAEKSDSAEYIMQVSNKVGKDECTCSLTVLDRTMPP 7402



 Score =  147 bits (357), Expect = 3e-33
 Identities = 143/626 (22%), Positives = 253/626 (40%), Gaps = 47/626 (7%)

Query: 795  KKVKDEGVYTLK----AENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKE 846
            +K KDE ++ +K    AE      E    I   +P      P    P  + R Q  TV  
Sbjct: 1762 RKTKDELLHHMKEKEEAERKRMEEEGKVTIPTFKPERVQLSPSMEAPRILERIQSKTVAP 1821

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYK 905
               ++   RV   P P   W++N  ++  +E +   +  +N+ ELVI +V +E DS    
Sbjct: 1822 MDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCELVIRDVTAE-DSASIM 1880

Query: 906  CVASNSAGK-SSH------------------GARVTID------VEKVTFVKHLQKSYET 940
              A+N AG+ SSH                  G+ V++          V+F +HL+ +   
Sbjct: 1881 VKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAKAAVSFTQHLEDATAN 1940

Query: 941  EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            E+   V  EC+TS   +  KW  N  EI   D   +  + +            D     C
Sbjct: 1941 EKDTMVTFECETSEPFIKVKWLKNNTEIFSGDKYRMHSDRKVHFLSVLIIDLRDDAEYTC 2000

Query: 1000 IVKDQE---TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
            ++ D E   TS  L V+    E I+ +++ EV E      EVE++ E  +  W    + +
Sbjct: 2001 VLADDESVRTSARLTVEGAALELIKHMENIEVPETYAGEFEVELSREDVEGSWFFGDKEL 2060

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
             P        +RG    L +++    D+G+Y+ +  D   +A + +   P  ++  L + 
Sbjct: 2061 SPSSKHIMSSRRGR-HTLSVKDVRKEDQGKYTFVCGDLRTSASLKMKLRPVTLMLPLTDL 2119

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
             V +G+ A  E+  ++ +    W K G  I  S+ + + ID +  KL + +   +DA  Y
Sbjct: 2120 SVCEGDIAQLEVRFSQENVEGTWMKSGQAISPSDRVHIVIDKQVHKLLLENVSTEDAASY 2179

Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSV 1235
            S  V     +    +   +I+  + L +   V   T A L  +I  + +  V WY     
Sbjct: 2180 SFVVPAQDISTAGKLSVQTIDIVVPLKDLSTV-EGTKAVLEAKISAQDISSVKWYHNDKQ 2238

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295
            +  +++   ++   K+ L+  +    DQ +Y  V+    ++  L VE V     IV +  
Sbjct: 2239 VTPSDRIQTVAKGAKQRLVFSRTHASDQGQYKLVVGKVDTSCTLTVEKVH----IVKHME 2294

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +        VT  V+  + P  +  W V ++++K     K     K  SLTI      + 
Sbjct: 2295 DRVCSESQKVTFRVEV-SHPGIDPVWTVRNQLLKPGAKYKMESKDKVHSLTILDTMKDEE 2353

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKP 1381
            G Y          A + ++   + +P
Sbjct: 2354 GQYMFHAGEQTSSAMLTVSGGAITRP 2379



 Score =  147 bits (356), Expect = 3e-33
 Identities = 181/779 (23%), Positives = 294/779 (37%), Gaps = 46/779 (5%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            + E  PP F  KP+   +  G + + +C L      D+ W  K    +  E     ++SD
Sbjct: 6927 VTELYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVW-HKDNLAISSEG-KYVMKSD 6984

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             + Y   L I +++   +G Y   A N  G A+    L +     + P  ++P       
Sbjct: 6985 KNKYS--LHIQSLELAHQGVYLCKASNSVGTATFSTELWV----IDKPSFVKPFDQASAA 7038

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDTHSITILKPKKVKDEGVYTL 805
              + V L  QV  +   TI W ++ K V +++  K S  D  ++  +   K+KD G Y  
Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVC 7098

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A N  G +   AV+ V+       EPP      Q +   + G   L   +       IT
Sbjct: 7099 TATNEAGSSSCEAVVMVQ-------EPPSIRKELQTVEALKGGPAYLEYEIAGTAPFEIT 7151

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W +N + I+  +            L I   +S  D GDY+ V SN  GK S  A   +  
Sbjct: 7152 WSKNRKPITSDKKYNIISQQSLSRLEILTFES-ADVGDYQMVVSNEVGKVSTKAVAKLK- 7209

Query: 926  EKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMDHR-EIIQEGRXX 982
            E  +F K +  S     G TV L+   + S  ++ KW  + + +   D    +  +    
Sbjct: 7210 EPPSFTKRVD-SVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVA 7268

Query: 983  XXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
                        G   C  ++    Q++   L V+E     +       V   + A LE 
Sbjct: 7269 FLSIATVAISHGGKYVCQAENEAGQQKSEATLTVQEP-ARVVEPAASISVTAGESATLES 7327

Query: 1039 EIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY----SCILR 1092
             I+ S    V W +DG E+   +K K   +      K+     S  D  EY    S  + 
Sbjct: 7328 TISGSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKS--DSAEYIMQVSNKVG 7385

Query: 1093 DESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149
             + CT  +TV++  +PP     L+    N GN A+ + +++    + + WFKD  EI   
Sbjct: 7386 KDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAG 7445

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEF 1205
               Q         L+I   +  D+G Y C   NS    + +  L V+EP   FT++    
Sbjct: 7446 PKFQAGFKDHSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPP-TFTVKPDGQ 7504

Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
             ++P +T ++         L V W+K+   I     + +  D    +L ++     D   
Sbjct: 7505 DVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSAR 7564

Query: 1266 YTC-VLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            Y C V  DA       +  V+ PP  V   E    +  G    L       P    +W  
Sbjct: 7565 YACQVSNDAGKVDCTALLFVKEPPTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFK 7624

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            +   I        + D   ASL I +    ++G Y     +  G       VT+   PS
Sbjct: 7625 DEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPS 7683



 Score =  146 bits (354), Expect = 6e-33
 Identities = 194/988 (19%), Positives = 375/988 (37%), Gaps = 71/988 (7%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSI 789
            E P+++E ++S  V   + V    +VVG P P   W KN   V+           D    
Sbjct: 1806 EAPRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCE 1865

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT--EENAE--------PPL----- 834
             +++    +D     +KA N  G A + A + V+     +++          P       
Sbjct: 1866 LVIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAK 1925

Query: 835  ----FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
                F    ++ T  EK T+      T  P   + W +NN  I   +    + D +   L
Sbjct: 1926 AAVSFTQHLEDATANEKDTMVTFECETSEPFIKVKWLKNNTEIFSGDKYRMHSDRKVHFL 1985

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
             +  +D   D  +Y CV ++     +  AR+T++   +  +KH++ + E  E      E 
Sbjct: 1986 SVLIIDLR-DDAEYTCVLADDESVRT-SARLTVEGAALELIKHME-NIEVPETYAGEFEV 2042

Query: 951  QTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009
            + S   V   W+   KE+S      +                 D G    +  D  TS  
Sbjct: 2043 ELSREDVEGSWFFGDKELSPSSKHIMSSRRGRHTLSVKDVRKEDQGKYTFVCGDLRTSAS 2102

Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRG 1069
            L +K      +  L D  V E D+A LEV  + E  +  W + G+ I P    +    + 
Sbjct: 2103 LKMKLRPVTLMLPLTDLSVCEGDIAQLEVRFSQENVEGTWMKSGQAISPSDRVHIVIDK- 2161

Query: 1070 HIRKLYIRNTSVHDEGEYSCIL--RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127
             + KL + N S  D   YS ++  +D S   +++V  +  +I+  L++    +G KA  E
Sbjct: 2162 QVHKLLLENVSTEDAASYSFVVPAQDISTAGKLSVQTI--DIVVPLKDLSTVEGTKAVLE 2219

Query: 1128 IELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
             +++  D + V+W+ +  ++  S+ IQ    G KQ+L        D G+Y   VG    +
Sbjct: 2220 AKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLVFSRTHASDQGQYKLVVGKVDTS 2279

Query: 1187 AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLIS 1246
              LTVE+  I   ++  E  +   +      VE+    +D  W  +  +++   K+ + S
Sbjct: 2280 CTLTVEKVHI---VKHMEDRVCSESQKVTFRVEVSHPGIDPVWTVRNQLLKPGAKYKMES 2336

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
              K  +L I    +D++ +Y     +  S+  L V        + D          S   
Sbjct: 2337 KDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTVSGGAITRPLQDV-----TVAESQTA 2391

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            +L    A  +    W+   + +   ++    +      LTI      D G Y  ++ N+ 
Sbjct: 2392 VLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLTITITRPQDVGEYSYQVANSK 2451

Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426
              A++ +    + K        + E   +   +     +  G S  I   VE Q  D  E
Sbjct: 2452 TTANLRVEAVKIKKTL--RNQTVTETQDAVFTLELTHADVKG-SQWIKNGVELQSSDKYE 2508

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
              S   +   +    N +  S Y F+   ++    ++A    E  K+IK+TK  +  ++ 
Sbjct: 2509 ISSDGMVQSLKIRNCNTQDESVYSFKLGKLS----ANARLNVETIKIIKKTKDVTTLMDG 2564

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546
                  +  ++D+ +  +F G         +  ++ +  K   +N               
Sbjct: 2565 TASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQN--------VNSSNAG 2616

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
             Y  +     G ++ S  + ++   ++  + +  + +      E  V+     +P     
Sbjct: 2617 EYTAVV----GHLQCSATLTVEALQIVKPMKDASVAETQAATFECEVSHF--NVPS---T 2667

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN-----TAGTSSVEVTL 1660
            W K+G ++E  +++ I  + K   ++I    +  S++YT    N     T   S V +T 
Sbjct: 2668 WLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFICGNDRVSATLTVSPVLITS 2727

Query: 1661 KVYDKPSKPEGPVIMR-EISRESVTIEW 1687
             + D  ++    +     ++ E +T +W
Sbjct: 2728 MLKDLNAQERDTITFEVTVNHEGITYKW 2755



 Score =  112 bits (269), Expect = 1e-22
 Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 25/248 (10%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568
            P F++ +R      G+  +F   V G P+P+++WF     I+P+ +   ++++  N ATL
Sbjct: 3220 PTFIQPIRSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATL 3279

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-----------------------EAPLS 605
            +I + F E AG +TC A N+AG A+ +  L +                       + P  
Sbjct: 3280 IIVDAFTEHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVKEQTQIQIQQDIKEPFH 3339

Query: 606  DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665
              GSE  V            +     + P+F+KK K Q V EG  + L+C LVA P P I
Sbjct: 3340 GSGSEELVRRDPTDGCSSTTSGT-GNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSI 3398

Query: 666  AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
             W    + +       +  +S MHM+ + L I  VK+   G+Y V+A+N EG A     L
Sbjct: 3399 LWFHNNKTLGKARRRRICSDSQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASL 3458

Query: 726  KIKTGEKE 733
             +   E++
Sbjct: 3459 LVSMREEQ 3466



 Score =  110 bits (265), Expect = 4e-22
 Identities = 154/710 (21%), Positives = 280/710 (39%), Gaps = 47/710 (6%)

Query: 1079 TSVHDEGEYSC-ILRD--ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATFEIELTKG 1133
            T++H+E      ++R+  E    E TVV     P ++T L++  V++ +KAT    +T  
Sbjct: 6711 TTIHEEETVDISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTITHA 6770

Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEV----GNSKCTAI 1188
             A V W  +G  ++     + + +     L I     +   GEY CE     G +  ++ 
Sbjct: 6771 -AKVNWLFNGQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTTTSSR 6829

Query: 1189 LTVEEPSINFTLRLPEFIL-VPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246
            LTV  P +    RL    L +   + A    E+ D   ++  WYK    I+ +EK+ ++S
Sbjct: 6830 LTVV-PRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVS 6888

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVE-FPPKIVDYEREYRIKRGS 1303
                  L +    + D  EY+C + +     T    + V E +PP  V       +  G 
Sbjct: 6889 SSTSSALELVSPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTLFVGK 6948

Query: 1304 DVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
            +             +  W   N  I  + K+   S D    SL I+ +E    G+Y  + 
Sbjct: 6949 EAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVMKS-DKNKYSLHIQSLELAHQGVYLCKA 7007

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQ 1420
             N+ G A     + ++DKPS   KP   +  S+++N  +  +   N      I +  + +
Sbjct: 7008 SNSVGTATFSTELWVIDKPSFV-KP--FDQASAAVNDPVRLECQVNEDTGVTIIWTRDGK 7064

Query: 1421 EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            ++  +    +    K     I   K   S ++   A NE      S + E   +++E   
Sbjct: 7065 KVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVCTATNEA----GSSSCEAVVMVQEP-- 7118

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXX 1535
              P++ K L+ +         L     G    ++TW ++ K + + K     + ++    
Sbjct: 7119 --PSIRKELQTVEALKGGPAYLEYEIAGTAPFEITWSKNRKPITSDKKYNIISQQSLSRL 7176

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                        Y+ +  N+ G+V T  V  +++ P  T   + +     +G    +   
Sbjct: 7177 EILTFESADVGDYQMVVSNEVGKVSTKAVAKLKEPPSFTKRVDSVTAV--LGTTVKLQGT 7234

Query: 1596 IEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            ++G  P  V W K+   L ++D    +T     + + I  +  SH  KY  +A N AG  
Sbjct: 7235 VKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQ 7294

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL-TKYAIEKHEPDNNRW 1713
              E TL V +     E    +   + ES T+E       G  EL  K+  +  E  + R 
Sbjct: 7295 KSEATLTVQEPARVVEPAASISVTAGESATLE---STISGSPELKVKWFKDGKEMTSGRK 7351

Query: 1714 IKVADVDRDVETYCIQ-KLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
             K+   D       +  + +++ EY+ +V   N VG  E   S  ++ +T
Sbjct: 7352 CKMTVKDNTATMKILSAEKSDSAEYIMQV--SNKVGKDECTCSLTVLDRT 7399



 Score =  107 bits (257), Expect = 3e-21
 Identities = 132/552 (23%), Positives = 217/552 (39%), Gaps = 43/552 (7%)

Query: 605  SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664
            S  G   T             A +L   PP   +KP++  V  GS +     L   P   
Sbjct: 8028 SKDGGSYTCIAKNKAGAVQCSAILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLT 8087

Query: 665  IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
            I W    +EI+   + SV  ++      + L +   K    G Y     N  G  S    
Sbjct: 8088 IKWFKNQKEILSSADCSVIKDNT----STSLALFFAKSSDSGEYRCEIQNDVGSTSCQAT 8143

Query: 725  LKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
            L +    KEPP+    P +  + R G++ +   QV G P   + W K    +        
Sbjct: 8144 LFV----KEPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQM 8199

Query: 784  GDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
               +S+  L+    + KD G+Y  +A N  G    S  + V+       E P  I     
Sbjct: 8200 SFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVK-------EIPTIIKDLAP 8252

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEID 900
              + +  T  L  +VT      +TWYR+  EI S ++      +G  + L +    +  D
Sbjct: 8253 AELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQING-TLGLEVHKCGA-AD 8310

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVST 958
             G+Y+C  +N  G  +  A + +  E  TF K L+ + +T  GK  + +C  + S T+S 
Sbjct: 8311 VGEYQCTVANEVGSCTSKATLKLK-EPPTFTKKLENT-DTVLGKMAVFQCVVEGSPTLSV 8368

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKE 1014
            +W  +   I      E   E                G   C V ++    + S  L V+E
Sbjct: 8369 QWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQE 8428

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG-EIIKPKKNKYDFEKRGHIR 1072
              P+   K +  +V   D   L+ ++    A  V W ++G E+   +++K  FE   +I 
Sbjct: 8429 P-PQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFE--NNIS 8485

Query: 1073 KLYIRNTSVHDEGEYSCILRDE----SCTAE-VTVVELPPE---IITRLQNQKVNKGNKA 1124
             L I+     DEGEY   + +     SC    V +VE   +   I + ++++ + + N  
Sbjct: 8486 SLKIQAAEREDEGEYILEVANHISRTSCKVRLVVLVEWQKDGKKIFSGVKHKLIQQDNSV 8545

Query: 1125 TFEIE-LTKGDA 1135
            + EIE L   DA
Sbjct: 8546 SVEIEQLEPSDA 8557



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 69/229 (30%), Positives = 110/229 (48%), Gaps = 9/229 (3%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTK--SDGDTHS 788
           + P   +PL+S++  +G +    AQV G+P P ++W ++ +   V ALP    S  D  +
Sbjct: 4   QAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRA 63

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
           +  L        G Y+++A N  G A ++A + V   T E A PP F+ R Q  TV++  
Sbjct: 64  VLRLTAVTAAHSGRYSVRATNGAGQATSTAELLV---TVETA-PPNFVQRLQSSTVRQGS 119

Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            ++L  RVT  P P++ +YR    I  S       DG+   L+I     E DSG Y   A
Sbjct: 120 QVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPE-DSGTYSVTA 178

Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957
           +NS+G+++  A + +  E+    K  +    T E +T     Q   T S
Sbjct: 179 ANSSGRATSTAELLVQGEEAMPTKKTKTVVSTSEIRTSKARVQKIKTTS 227



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 115/423 (27%), Positives = 179/423 (42%), Gaps = 71/423 (16%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568
            P  +  + P+    G   +F  +V G P+PQ++W++ + ++  S  F+  +  + N  +L
Sbjct: 2993 PQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQML--SAGFKCKFLCEANQHSL 3050

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            ++ EVFPEDA  ++C AKN  G ASST  L VE       SE+               D+
Sbjct: 3051 LLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEV------SEVV------------SPDL 3092

Query: 629  LEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
               + PP  +    +    EG      CR V   +  I+W  K +EI   E   ++   D
Sbjct: 3093 AAAVAPPVITSPISSTSAREGEPARFHCR-VHGDDVKISWFHKEKEIKQSEFFRMSQFED 3151

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI------KTGEKEP------- 734
                C  L+I+ V    EG Y+ VA N  G AS    L +      + G   P       
Sbjct: 3152 S---CQ-LEISRVYPEDEGEYSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTS 3207

Query: 735  ------------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS 782
                        P  I+P++S  V  G      A V G P+P ++W  N +P++  PT +
Sbjct: 3208 LTSIKKAPIGQKPTFIQPIRSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQ--PTTN 3265

Query: 783  -----DGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAE 831
                 +  T++ T I+     +  G YT +A NS G A  SA +T+     EE T    +
Sbjct: 3266 VVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVKEQ 3325

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGEN 887
              + I +  +      G+ +LV R   +   S T    N  + PS T    F    +GE 
Sbjct: 3326 TQIQIQQDIKEPFHGSGSEELVRRDPTDGCSSTTSGTGN--VKPSFTKKLKFQSVLEGEP 3383

Query: 888  IEL 890
            +EL
Sbjct: 3384 VEL 3386



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 128/582 (21%), Positives = 218/582 (37%), Gaps = 60/582 (10%)

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            K  K   V E      EC +     P   WL  G EI   E   + ++  +H     LKI
Sbjct: 2640 KPMKDASVAETQAATFECEVSHFNVPS-TWLKDGVEIEMSEKFRIVVQGKLHQ----LKI 2694

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
             N  K     YT +  N    A+L +          P  +   LK +  ++ +++     
Sbjct: 2695 VNTSKDDSAEYTFICGNDRVSATLTV---------SPVLITSMLKDLNAQERDTITFEV- 2744

Query: 758  VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
             V +   T  W KN   VK+      +S   TH++TI +     D G Y   A    G A
Sbjct: 2745 TVNHEGITYKWLKNGVEVKSSDRCQVRSRQLTHTLTI-RNVHFGDGGEYQFVA----GSA 2799

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
             TSA + VE    E      F  + ++I + EK        V+  P   + W ++ + + 
Sbjct: 2800 ATSANLFVEARVIE------FTRKIKDIKIIEKKKAIFECEVSE-PNIQVMWMKDGQELD 2852

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             SE        + +  ++       D+G+Y  VA +S  K    A++ ++   +      
Sbjct: 2853 LSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSSVSK----AQLVVEGRDIRIAPPA 2908

Query: 935  QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
            ++     E     +E + +   V  +W  N  E+S  +    +   +            D
Sbjct: 2909 ERDITVLEKHRATIEFEVNEDDVEGRWLKNGAELSLEERFSYVVIRKVHRITISETFRSD 2968

Query: 994  VGVIKCIVKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWER 1051
             G    I     +S  L V     P+ +R ++   V+   +A   VE++      V W +
Sbjct: 2969 AGEYTFIAGKNRSSVNLRVNIPEPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYK 3028

Query: 1052 DGEIIKPK-KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV---- 1102
            + +++    K K+  E   H   L +      D   YSC  +++    S TA + V    
Sbjct: 3029 NSQMLSAGFKCKFLCEANQH--SLLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSE 3086

Query: 1103 --------VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
                       PP I + + +    +G  A F   +   D  + WF    EI+ S   ++
Sbjct: 3087 VVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHGDDVKISWFHKEKEIKQSEFFRM 3146

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVE 1192
            +      +L+I     +D GEYSC   NS     C+A LT++
Sbjct: 3147 SQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTLD 3188



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 114/490 (23%), Positives = 190/490 (38%), Gaps = 43/490 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E   M P F+  +    TP+G+T+ FEC + G P P ++WF+    I P+    ++  + 
Sbjct: 5365 EVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEG 5424

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS----DHGSEMTVXXXXXX 619
            +   L I  V  +D+G + C A N  G   S   L+V    +      G E+T       
Sbjct: 5425 DNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVNAKAFAGRTRGREVTAVSLRSA 5484

Query: 620  XXXXXXADILEGIPPTFSKKP-----KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
                   D++ G      ++      + ++  E  +     RLVA  +       +GE+ 
Sbjct: 5485 KIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADESQRAVRLVANADRQSETSEQGEKY 5544

Query: 675  VPDENISVAIESDMHMYCSVL-KITNVKKFQ------EGTYTVVAVNREGEASLPIVLK- 726
            V   N  V  E           K +++  FQ         + +   N    A  P++L+ 
Sbjct: 5545 V-SINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTESPPKFIIPLTNITAAAGTPVILQC 5603

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN-----PRPTITWCKNNKPVKALPT- 780
            + +G   P    E  K          I+  + VG+       P + W  N K + +    
Sbjct: 5604 LVSGTPNP--TAEWYKDGGRVTDSRCIIQEKTVGHFNLLITNPVVQWSHNGKVITSSSVY 5661

Query: 781  KSDGDTHSITILKPKKVKD-EGVYTLKAENSEG------IAETSAVIT------VEEPTE 827
            K   +    T++  K   + EG Y+  A N  G        E  AV        VE+  +
Sbjct: 5662 KLIEEREDYTLVITKVTSEYEGEYSCTATNRFGQTTCTTYLEVKAVDVSQAEKWVEKMFK 5721

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDG 885
               +PP F    Q     E   +    +V+ +PVP + WY+    + P     I  N DG
Sbjct: 5722 VTGQPPKFSVPIQPSRCPEGTEVFFHYQVSGDPVPDVKWYKGAFQVQPGRNCVIISNPDG 5781

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
                L + ++  E DSG Y C ASN+ G++S  A + +  E V   K  Q +   ++G  
Sbjct: 5782 SGC-LSLKSLKQE-DSGMYMCRASNTFGEASSSAELAVFKESVVVSKQEQLTVVQKKGYK 5839

Query: 946  VILECQTSHT 955
            V +  Q + +
Sbjct: 5840 VSVTEQATES 5849



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 59/194 (30%), Positives = 97/194 (50%), Gaps = 9/194 (4%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
           PTF++  ++    EGS    E ++   P P+++W   G+ +       V I  SD     
Sbjct: 6   PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGR--- 62

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           +VL++T V     G Y+V A N  G+A+    L + T E  PP  ++ L+S  VRQG  V
Sbjct: 63  AVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLV-TVETAPPNFVQRLQSSTVRQGSQV 121

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  +V G P PT+ + +    +++        DGD +S+ I +    +D G Y++ A N
Sbjct: 122 RLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFP-EDSGTYSVTAAN 180

Query: 810 SEGIAETSAVITVE 823
           S G A ++A + V+
Sbjct: 181 SSGRATSTAELLVQ 194



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 81/337 (24%), Positives = 132/337 (39%), Gaps = 42/337 (12%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP   +  + Q V+ G        +  +P+P ++W    + +          E++ H   
Sbjct: 2992 PPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHS-- 3049

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---------EPPQVIEPLKS 743
              L +  V       Y+  A N  G AS    L ++  E           PP +  P+ S
Sbjct: 3050 --LLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISS 3107

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEG 801
               R+GE      +V G+    I+W    K +K               L+  +V  +DEG
Sbjct: 3108 TSAREGEPARFHCRVHGDD-VKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEG 3166

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENA----------------------EPPLFINRF 839
             Y+  A NS G A  SA +T++  T   A                      + P FI   
Sbjct: 3167 EYSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPI 3226

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            +  TV      +  A V+  P P ++W+ N   I P+  +  +F+       +  VD+  
Sbjct: 3227 RSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFT 3286

Query: 900  D-SGDYKCVASNSAGKSSHGARVTI---DVEKVTFVK 932
            + +G Y C A+NSAG+++  A +TI     E+VT VK
Sbjct: 3287 EHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVK 3323



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 39/99 (39%), Positives = 58/99 (58%), Gaps = 1/99 (1%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           ++E ++ P  +  L+     +G ++  ECQ+ G P P I WFR+   I+ S DF   Y  
Sbjct: 585 AQEPAVPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSY-T 643

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           D +A LVIRE F ED+G F+C A N AG  S++  L+V+
Sbjct: 644 DGIARLVIREAFAEDSGRFSCTATNEAGTISTSCYLLVK 682



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 38/96 (39%), Positives = 63/96 (65%), Gaps = 1/96 (1%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           ++  P FV++L+      GS V+ + +V G P P + ++R+ A I+ S DFQ+  D D +
Sbjct: 100 ETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGD-L 158

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +L+I E FPED+GT++  A N++G A+ST EL+V+
Sbjct: 159 YSLLIAEAFPEDSGTYSVTAANSSGRATSTAELLVQ 194



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 77/321 (23%), Positives = 134/321 (41%), Gaps = 33/321 (10%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            Q + P F++ L  K   +  ++ F  +V G P P++ WF     +      +M  D D++
Sbjct: 5170 QGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSI 5229

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
             +L + +V   D G + C A N  G A S T ++V   LS     +              
Sbjct: 5230 -SLTVLDVTKADQGEYICEAVNNVGEARSVTLVVV---LSQE-MRLMPPPPAVTHQHVME 5284

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
             D+ +      S+ P  Q      +ILLE   V + E ++    K  +I+    I     
Sbjct: 5285 FDVEDN---DTSRSPSPQ------EILLE---VELDENEVKEFEKQVKII---TIPEYTA 5329

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
             +  M  S+  + +V  ++EG    V    +    L I  ++    + PP+ I P+  M 
Sbjct: 5330 DNKSMIVSLDVLPSV--YEEGAVDFVTHEHD---DLKIAFEV---TEMPPRFINPICDME 5381

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEG 801
              +G +++    ++G P P ++W K +K +    K     S+GD H + I      +D G
Sbjct: 5382 TPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKIC-TVTTQDSG 5440

Query: 802  VYTLKAENSEGIAETSAVITV 822
            VY  +A N  G   + A + V
Sbjct: 5441 VYICRAINVVGETLSRASLVV 5461



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 72/328 (21%), Positives = 133/328 (40%), Gaps = 22/328 (6%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD- 561
            S  ++ AP F++K   +   +G +V FECQV G P+P + W +    +     +++ Y  
Sbjct: 733  SAGETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKR 792

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXX 618
            +     L I   F +DAG +    KN  G  S++  L+ E     L   G          
Sbjct: 793  ETGECKLEISMTFADDAGEYAIFVKNPHGEVSASASLLEEGTGTVLLSSGCHRPWLRGQG 852

Query: 619  XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                    +  E     + K+    +  E +  +++   V + + +   +     +V + 
Sbjct: 853  STSASVFTEQYE----AYMKQHDLTFKTEVTTTVIQEPAVIVTQMEQKQITTPVSVVSER 908

Query: 679  NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
               ++   +  +    L+I  +  ++E    +V  +RE      +++    GE E P   
Sbjct: 909  EFLISAFEERIIQEIELRIMRI-TYRE----LVTEDRE------LMVTAAEGEAEQPAFN 957

Query: 739  EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPK 795
             P+K+  + +G  V    ++ G P P I W K+    +P      ++  D  +   L   
Sbjct: 958  TPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQV 1017

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVE 823
              +DEGVYT  A N  G A +S  + VE
Sbjct: 1018 LPEDEGVYTAFAANVLGNAVSSGKLYVE 1045



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 43/313 (13%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  ++ L P      ST   ECQV G    ++TW+R    IK S     +   +    L 
Sbjct: 8244 PTIIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAK-HSFSQINGTLGLE 8302

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            + +    D G + C   N  G  +S   L ++ P                         L
Sbjct: 8303 VHKCGAADVGEYQCTVANEVGSCTSKATLKLKEP-------------------PTFTKKL 8343

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E       K    Q V EGS           P   + W      I+ D  I    E+++ 
Sbjct: 8344 ENTDTVLGKMAVFQCVVEGS-----------PTLSVQWQKDDNWILEDPKIERTFENNV- 8391

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               ++LKI   +    G Y+   VN  G+      L +    +EPPQ+ E  + + V  G
Sbjct: 8392 ---AILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTV----QEPPQITEKPEVIKVTVG 8444

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
            + V L  +V G+P   + W K  K ++++        ++I+ LK +    +DEG Y L+ 
Sbjct: 8445 DPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENNISSLKIQAAEREDEGEYILEV 8504

Query: 808  ENSEGIAETSAVI 820
             N   I+ TS  +
Sbjct: 8505 ANH--ISRTSCKV 8515



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 94/466 (20%), Positives = 186/466 (39%), Gaps = 43/466 (9%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            +PP  +  L  ++V + +  TF  E+       V+WF + +++   + I++  DG    L
Sbjct: 5172 VPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSISL 5231

Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTV---------EEPSI------NFTLRLPE 1204
             + D    D GEY CE    VG ++   ++ V           P++       F +   +
Sbjct: 5232 TVLDVTKADQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDVEDND 5291

Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL-IIRKCTEDDQ 1263
                P+  +  L VE+ DE  +V  ++K+  I    ++T  +     +L ++    E+  
Sbjct: 5292 TSRSPSPQEILLEVEL-DEN-EVKEFEKQVKIITIPEYTADNKSMIVSLDVLPSVYEEGA 5349

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             ++   +       K+  EV E PP+ ++   +     G+ +         P P   W  
Sbjct: 5350 VDF---VTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFK 5406

Query: 1324 -NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             + KI    K    S +  +  L I  V   D+G+Y  R  N  G      ++ +++  +
Sbjct: 5407 GDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVNAKA 5466

Query: 1383 PPGKPNILEIDSSSINICWDEPEN----TGNSTI-------IYYVVEY-QEIDTTEWI-- 1428
              G+    E+ + S+     +P+      G +++       I    E+ QE D ++    
Sbjct: 5467 FAGRTRGREVTAVSLRSAKIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADESQRAVR 5526

Query: 1429 SVKNITK-TQTSIQNLK-TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
             V N  + ++TS Q  K  + ++   A    E  +    ++++      +     P    
Sbjct: 5527 LVANADRQSETSEQGEKYVSINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTESPPKFII 5586

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
            PL NIT      + L C+  G P P   WY+DG ++  ++   + +
Sbjct: 5587 PLTNITAAAGTPVILQCLVSGTPNPTAEWYKDGGRVTDSRCIIQEK 5632



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 15/188 (7%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIK----PKKNKYDFEKRGHI 1071
            P F + LQ     E   A  E +++ S   +V W RDG+++     P       + R  +
Sbjct: 6    PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRAVL 65

Query: 1072 RKLYIRNTSVHDEGEYSCILRD----ESCTAE--VTVVELPPEIITRLQNQKVNKGNKAT 1125
            R   +  T+ H  G YS    +     + TAE  VTV   PP  + RLQ+  V +G++  
Sbjct: 66   RLTAV--TAAHS-GRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVR 122

Query: 1126 FEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
             ++ +T      V+++++G+EIQ S   Q+  DG    L I +   +D+G YS    NS 
Sbjct: 123  LDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSVTAANSS 182

Query: 1185 CTAILTVE 1192
              A  T E
Sbjct: 183  GRATSTAE 190



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 63/297 (21%), Positives = 117/297 (39%), Gaps = 24/297 (8%)

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            E  AE+S++ T+EE  +    PP F+    +  V E  ++   A V   P P + W+ N 
Sbjct: 5154 ETTAESSSLATLEEKGQ--GVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNK 5211

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +   + I    DG++I L + +V ++ D G+Y C A N+ G++     V +  +++  
Sbjct: 5212 TQLVEDDRIKMERDGDSISLTVLDV-TKADQGEYICEAVNNVGEARSVTLVVVLSQEMRL 5270

Query: 931  ------VKHLQ-KSYETEEGKT--------VILECQTSHTVSTKWYHNKKEISGMDHREI 975
                  V H     ++ E+  T        ++LE +       ++   +K++  +   E 
Sbjct: 5271 MPPPPAVTHQHVMEFDVEDNDTSRSPSPQEILLEVELDENEVKEF---EKQVKIITIPEY 5327

Query: 976  IQEGRXXXXXXXXX-XXXDVGVIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
              + +             + G +  +  +  +      V E  P FI  + D E  E   
Sbjct: 5328 TADNKSMIVSLDVLPSVYEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTT 5387

Query: 1034 AILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             + E  +    + +V W +  + I P   KY     G    L I   +  D G Y C
Sbjct: 5388 ILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYIC 5444



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 1/99 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E    P F +K+      +G  ++FEC++ G    +++W R    +K   +F M Y DDN
Sbjct: 9391 EAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGEPLKAGGEFSMLY-DDN 9449

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             A L I       +G +TCVA N+ G  S   +L ++ P
Sbjct: 9450 TAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEP 9488



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 55/261 (21%), Positives = 92/261 (35%), Gaps = 3/261 (1%)

Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
            ++ S   L+ +    PP  +    + R+     +T   +    P P  +W  N   + + 
Sbjct: 5158 ESSSLATLEEKGQGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVED 5217

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGKPNI 1389
               K   D  S SLT+  V   D G Y     NN G A     V +L +     P  P +
Sbjct: 5218 DRIKMERDGDSISLTVLDVTKADQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAV 5277

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSS 1448
                    ++  ++   + +   I   VE  E +  E+   VK IT  + +  N     S
Sbjct: 5278 THQHVMEFDVEDNDTSRSPSPQEILLEVELDENEVKEFEKQVKIITIPEYTADNKSMIVS 5337

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
                     E  +   +   +  K+  E     P    P+ ++ T     I   C   G 
Sbjct: 5338 LDVLPSVYEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGT 5397

Query: 1509 PQPKVTWYRDGKKLKTAKATY 1529
            P P V+W++  KK+      Y
Sbjct: 5398 PSPIVSWFKGDKKIPPNSKKY 5418



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 8/157 (5%)

Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGE 886
           + + P F    Q +   E       A+V+ +PVP ++W+R+ +++S +    +  +F   
Sbjct: 2   STQAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDG 61

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR--VTIDVEKVTFVKHLQKSYETEEGK 944
              L +T V +   SG Y   A+N AG+++  A   VT++     FV+ LQ S    +G 
Sbjct: 62  RAVLRLTAV-TAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSS-TVRQGS 119

Query: 945 TVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEG 979
            V L+ + +   S   K+Y    EI      +I+Q+G
Sbjct: 120 QVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDG 156



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 14/230 (6%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQDFQMYYDDDN 564
           + AP F + L+     +GS   FE QV G P P+++WFR  Q   +      Q+ + D  
Sbjct: 3   TQAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGR 62

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            A L +  V    +G ++  A N AG A+ST EL+V    +       +           
Sbjct: 63  -AVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQV 121

Query: 625 XADI-LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE---NI 680
             D+ + GIP      P  ++  EG++I        + + D+  L   E    D    ++
Sbjct: 122 RLDVRVTGIP-----SPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSV 176

Query: 681 SVAIESDMHMYCSVLKITNVKKF-QEGTYTVVAVNREGEASLPIVLKIKT 729
           + A  S      + L +   +    + T TVV+ + E   S   V KIKT
Sbjct: 177 TAANSSGRATSTAELLVQGEEAMPTKKTKTVVSTS-EIRTSKARVQKIKT 225



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 45/201 (22%), Positives = 86/201 (42%), Gaps = 15/201 (7%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533
            Q+PT  +PL+++               G P P+V+W+RDG+ L  A       +  + R 
Sbjct: 4    QAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRA 63

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC--VVGIQQKP---VITISNEDIKQKHKVGD 1588
                          Y   A N  G+  ++   +V ++  P   V  + +  ++Q  +V  
Sbjct: 64   VLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRL 123

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
            +  VT    GIP P V +Y+ G ++++  ++ I        + I E     S  Y++ A+
Sbjct: 124  DVRVT----GIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSVTAA 179

Query: 1649 NTAGTSSVEVTLKVYDKPSKP 1669
            N++G ++    L V  + + P
Sbjct: 180  NSSGRATSTAELLVQGEEAMP 200



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 6/102 (5%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK--SDGDTHSIT- 790
            P   + LK   V +GE V L  ++V +P P+I W  NNK + KA   +  SD   H  T 
Sbjct: 3367 PSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTT 3426

Query: 791  --ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
              I+   K KD G Y + A NSEG AE++A + V    E++A
Sbjct: 3427 SLIIDRVKEKDSGSYKVMAINSEGSAESTASLLVSMREEQSA 3468



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 2/138 (1%)

Query: 464  EEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD 523
            +EKG +    L +     Q +++      +  P       E +   P  V    P    +
Sbjct: 1526 DEKGLIEETQLPEGRRAPQRMEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFE 1585

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G   +F C+V GYP P++ W+    +I+ S+ ++++Y  D +  L I ++   D+G    
Sbjct: 1586 GDIARFRCRVTGYPAPKVNWYLNGQLIRKSKRYRLHY--DGIYYLEIVDIKSYDSGEVRV 1643

Query: 584  VAKNAAGFASSTTELIVE 601
            VA N  G    T +L V+
Sbjct: 1644 VADNPLGTTEHTVKLEVQ 1661



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 99/469 (21%), Positives = 179/469 (38%), Gaps = 55/469 (11%)

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKPVK--ALPTKSDGDT 786
            G+  PP  ++PL    V + +S+   A+V G P P + W C   + V+   +  + DGD+
Sbjct: 5169 GQGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDS 5228

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITV 844
             S+T+L   K  D+G Y  +A N+ G A +  ++ V         PP  +      E  V
Sbjct: 5229 ISLTVLDVTKA-DQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDV 5287

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGD 903
            ++  T +  +         +      E     + IT   +  +N  ++   V  ++    
Sbjct: 5288 EDNDTSRSPSPQEILLEVELDENEVKEFEKQVKIITIPEYTADNKSMI---VSLDVLPSV 5344

Query: 904  YKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVILECQTSHTVS--TK 959
            Y+  A +         ++  +V ++   F+  +    ET EG T++ EC    T S    
Sbjct: 5345 YEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPI-CDMETPEGTTILFECSLMGTPSPIVS 5403

Query: 960  WYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKE 1014
            W+   K+I     + +   EG             D GV  C    +V +  +   LVV  
Sbjct: 5404 WFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVN 5463

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV---WERDGEIIKPKKNKYDFEKRGHI 1071
                F  + +  EV    V++   +I  +  D++      DGE +   + +++F++    
Sbjct: 5464 A-KAFAGRTRGREVTA--VSLRSAKIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADE 5520

Query: 1072 RKLYI-------RNTSVHDEGE-YSCILRD------------------ESCTAEVTVVEL 1105
             +  +       R +   ++GE Y  I  D                  + C+ +  V E 
Sbjct: 5521 SQRAVRLVANADRQSETSEQGEKYVSINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTES 5580

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHI 1152
            PP+ I  L N     G     +  L  G  +    W+KDG  +  S  I
Sbjct: 5581 PPKFIIPLTNITAAAGTPVILQC-LVSGTPNPTAEWYKDGGRVTDSRCI 5628



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 2/128 (1%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            ++++  +Y+ +  N K+ K       T  +++M P F + LR      G+    +C+V G
Sbjct: 7369 EKSDSAEYIMQVSN-KVGKDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSG 7427

Query: 536  YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
                 I WF+    I     FQ  + D + ATL I  +   D+G + C A N+AGF  ++
Sbjct: 7428 SQPMTIAWFKDDHEITAGPKFQAGFKDHS-ATLQIAGLEKADSGVYKCRATNSAGFKETS 7486

Query: 596  TELIVEAP 603
              L V+ P
Sbjct: 7487 GTLYVKEP 7494



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 2/94 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FVE L P     G  V  +C+V G P  +++WF+    ++ S   ++ Y    VA L 
Sbjct: 9300 PYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEY-TKGVACLK 9358

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEA 602
            + +    D G ++C A+N  G  SS+  L ++EA
Sbjct: 9359 LSKATKADIGEYSCKAENRIGATSSSCRLNVLEA 9392



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 3/145 (2%)

Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
           E   V  V +  +E A PP  I   + +TV E  ++ L  ++   P P I W+R +  I 
Sbjct: 574 EPQEVSAVPKAAQEPAVPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIE 633

Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
            S     ++      LVI    +E DSG + C A+N AG  S    + + V +    +  
Sbjct: 634 SSIDFHTSYTDGIARLVIREAFAE-DSGRFSCTATNEAGTISTSCYLLVKVSEEIEYREE 692

Query: 935 QKSYETEEGKT--VILECQTSHTVS 957
             +  TE G T   I  C   H V+
Sbjct: 693 PVAEVTEVGVTQEKICWCLIKHWVA 717



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 52/205 (25%), Positives = 83/205 (40%), Gaps = 30/205 (14%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-----------------QT 547
            E+   P+FV K  P    +G T +F+ +V G P P   WF                  QT
Sbjct: 1101 ERLYKPVFVMKPTPLRCSEGQTARFDLKVVGRPMPDTYWFHNGEEKLDMFFSCTGLVLQT 1160

Query: 548  AIIKPSQDFQMYYD------DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +  +  Q     Y       +D V +L+I    P+D+G +T +A+N AG  S +  L V+
Sbjct: 1161 SFFRTGQQVVSDYSHKIVIKEDGVQSLIIVPAMPKDSGEWTVIAQNRAGRTSVSITLTVD 1220

Query: 602  --APLSDHGSEMTVXXXXX----XXXXXXXADILEGIP-PTFSKKPKAQYVDEGSDILLE 654
              + +    S   +                +   E +  P F +K K   V EG+ + L 
Sbjct: 1221 GKSEICPAASAPVMTRLPSGLGPNSFTWIQSPARESLTRPQFVEKLKNMTVKEGTLVELA 1280

Query: 655  CRLVAIPEPDIAWLFKGEEIVPDEN 679
             + +  P PDI WL   + I P ++
Sbjct: 1281 VKAIGNPLPDIVWLKNSDIISPHKH 1305



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQV 533
            D+ +  +Y    +N+ + K+      T +E+   P+F +K   +H  D  G  V+ E +V
Sbjct: 9555 DKGDTGKYFCHAMND-VGKVSCSSDVTVKERKNPPVFTKK-PSEHMEDTEGRLVKIEGRV 9612

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G     ++W+++ A I  S  + + +   NVA L I+     D+G +TC A N AG AS
Sbjct: 9613 SGSQPMSVSWYKEDAEIHSSDKYDISFKS-NVAVLCIKSSHVTDSGRYTCQASNEAGRAS 9671

Query: 594  STT 596
              T
Sbjct: 9672 CCT 9674



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G    FECQV G P   + WF++ + I PS+ +QM +  +++A+L +     +D+G + C
Sbjct: 8165 GQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSF-LNSLASLEVCGTETKDSGLYYC 8223

Query: 584  VAKNAAGFASSTTELIVE 601
             A+N AG  S + EL V+
Sbjct: 8224 EARNEAGSESCSMELKVK 8241



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 7/147 (4%)

Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL---EGIPPTFSKKPKAQYVDE 647
           F+     L + A  + H    +V            A++L   E  PP F ++ ++  V +
Sbjct: 58  FSDGRAVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQ 117

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           GS + L+ R+  IP P + +  +G EI    +  +  + D++     L I        GT
Sbjct: 118 GSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYS----LLIAEAFPEDSGT 173

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEP 734
           Y+V A N  G A+    L ++  E  P
Sbjct: 174 YSVTAANSSGRATSTAELLVQGEEAMP 200



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            +Q + P F  KL+       S    EC V G     + W++    I+     +  + + N
Sbjct: 7959 DQIIPPSFTRKLKQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQADHKHKCTFFE-N 8017

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            VA L I ++  +D G++TC+AKN AG    +  L+V+ P
Sbjct: 8018 VAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEP 8056



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 7/141 (4%)

Query: 1453 AYAVNEVDISD--ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            A A++E +  D    E +   K  +E  +  PT+   LKN+T    E + L C  GG P 
Sbjct: 562  AVALSEEEFEDWEPQEVSAVPKAAQEPAVP-PTLIVGLKNVTVTEGESLTLECQIGGQPT 620

Query: 1511 PKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            P + W+R+  +++++     +Y +                 + C A N+ G + TSC + 
Sbjct: 621  PVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFSCTATNEAGTISTSCYLL 680

Query: 1567 IQQKPVITISNEDIKQKHKVG 1587
            ++    I    E + +  +VG
Sbjct: 681  VKVSEEIEYREEPVAEVTEVG 701



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 3/102 (2%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            TS   ++ P F +KL+ +   +G  V+ +C++   P P I WF     +  ++  ++  D
Sbjct: 3359 TSGTGNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSD 3418

Query: 562  DD---NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                 +  +L+I  V  +D+G++  +A N+ G A ST  L+V
Sbjct: 3419 SQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASLLV 3460



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 5/131 (3%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534
            +D   YT  +  ++ + + K+ +    T  ++ + P F  KL+  HT  G   + EC+V 
Sbjct: 8988 LDSGEYTFEIMNEVGKDLSKINL----TVLDKIIPPSFSRKLKDCHTVVGKAGEMECKVS 9043

Query: 535  GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
            G P   I+W      I+   ++++ +  +N   L +  +   D+G + C A N AG + +
Sbjct: 9044 GSPPFAISWHHDGEEIQSGPNYEISF-SNNSCILRVPTLKLSDSGLYKCKAVNEAGTSET 9102

Query: 595  TTELIVEAPLS 605
               + V+ P S
Sbjct: 9103 AATMDVKEPPS 9113



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 19/54 (35%), Positives = 33/54 (61%)

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
            ++ P  E+   P F+ + + +TVKE   ++L  +   NP+P I W +N++IISP
Sbjct: 1249 IQSPARESLTRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISP 1302



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 31/106 (29%), Positives = 54/106 (50%), Gaps = 3/106 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV+KL    +  GS V   C ++G     ++W +    +K ++  Q+ Y + N A L 
Sbjct: 7775 PSFVQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITY-ESNTALLH 7833

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613
            I +V    AG ++C A+N AG  + +  L V+ P  ++D    ++V
Sbjct: 7834 ITDVQRNHAGKYSCQAQNQAGSQTCSALLTVKEPAEITDEAKSISV 7879



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 61/316 (19%), Positives = 120/316 (37%), Gaps = 27/316 (8%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E   P F KKP AQ + EG  ++ EC++   P+P + W   G  +       VA + +  
Sbjct: 736  ETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETG 795

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK--------IKTGEKEP------- 734
              C  L+I+       G Y +   N  GE S    L         + +G   P       
Sbjct: 796  E-CK-LEISMTFADDAGEYAIFVKNPHGEVSASASLLEEGTGTVLLSSGCHRPWLRGQGS 853

Query: 735  --PQVIEPLKSMIVRQGESVI---LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
                V        ++Q +      ++  V+  P   +T  +  +    +   S+ +   I
Sbjct: 854  TSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQMEQKQITTPVSVVSERE-FLI 912

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            +  + + +++  +  ++    E + E   ++      E  AE P F    +   + E   
Sbjct: 913  SAFEERIIQEIELRIMRITYRELVTEDRELMVTA--AEGEAEQPAFNTPVKNYRIMEGMG 970

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVA 908
            +    R++  P+P I W+++ + + PS+    +        L +  V  E D G Y   A
Sbjct: 971  VTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQVLPE-DEGVYTAFA 1029

Query: 909  SNSAGKSSHGARVTID 924
            +N  G +    ++ ++
Sbjct: 1030 ANVLGNAVSSGKLYVE 1045



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--I 791
           PP +I  LK++ V +GES+ L  Q+ G P P I W + +  +++        T  I   +
Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLV 650

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSA--VITVEEPTEENAEP 832
           ++    +D G ++  A N  G   TS   ++ V E  E   EP
Sbjct: 651 IREAFAEDSGRFSCTATNEAGTISTSCYLLVKVSEEIEYREEP 693



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+FV+++ P     G   +F CQ  G P P +TW +    +  + DF +  D  N + L
Sbjct: 4350 APVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDI-IDRANRSKL 4408

Query: 569  VIREVFPEDAGTFTCVAKNAAG--FASSTTEL 598
             +     +  GT+ C+  N  G    S+T E+
Sbjct: 4409 TVFYPTADHEGTYDCIITNKHGKSLCSATLEI 4440



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 3/135 (2%)

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            + E  E +A       V    E     P  +   +   V E    +   RVT  P P + 
Sbjct: 1545 RMEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFEGDIARFRCRVTGYPAPKVN 1604

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            WY N ++I  S+    ++DG    L I ++ S  DSG+ + VA N  G + H  ++ +  
Sbjct: 1605 WYLNGQLIRKSKRYRLHYDG-IYYLEIVDIKS-YDSGEVRVVADNPLGTTEHTVKLEVQ- 1661

Query: 926  EKVTFVKHLQKSYET 940
            +K  F   L+++ E+
Sbjct: 1662 QKEDFRSVLRRAPES 1676



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 7/156 (4%)

Query: 1216  LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
             +T+  P+ TL  +WYK    ++ ++K+ +     +  L IR+C   DQ  Y  V     S
Sbjct: 10023 VTINYPEITL--SWYKGTQKLDSSDKYDISISGDRHLLRIRRCQTSDQGNYRVVCGPHIS 10080

Query: 1276  TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
             + KL V   E    + D       K G   TL     + P    +W  N K ++      
Sbjct: 10081 SAKLTVMEAEVEKHLQDTSG----KEGQSCTLSCQL-SIPNVQAQWFKNGKRLEMKGKFT 10135

Query: 1336  PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
               +  K   L I  ++  D G Y  + ++    AD+
Sbjct: 10136 SEVKHKIQKLLISDLKPEDQGRYTCQYQSLESSADL 10171



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E   P F+   K   + EG  +   CR+   P P IAW   G+ + P ++  +    D  
Sbjct: 950  EAEQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGR 1009

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
               + L++  V    EG YT  A N  G A     L ++     PPQ
Sbjct: 1010 ---ASLRLAQVLPEDEGVYTAFAANVLGNAVSSGKLYVEPSGAFPPQ 1053



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 1/104 (0%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV+            V+ ECQV       I W R    +  S D ++ ++D  VA + 
Sbjct: 7026 PSFVKPFDQASAAVNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFED-KVAVVE 7084

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            I +   +D+G + C A N AG +S    ++V+ P S      TV
Sbjct: 7085 IPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSIRKELQTV 7128



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 18/38 (47%), Positives = 26/38 (68%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            PQ +E LK+M V++G  V L+ + +GNP P I W KN+
Sbjct: 1260 PQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNS 1297



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            A + G+P PEV W+ N   ++   +  ++      T+ + I +    H+ +YT  A+N+A
Sbjct: 3241 ACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSA 3300

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
            G ++   TL +     + E   +++E ++  +  + K P    G E
Sbjct: 3301 GEAACSATLTI--TKVQQEEVTVVKEQTQIQIQQDIKEPFHGSGSE 3344



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 8/124 (6%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE----NI 888
            P F  + +  +V E   ++L   +  +P PSI W+ NN+ +  +       D +      
Sbjct: 3367 PSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTT 3426

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV---EKVTFVKHLQKSYETEEGKT 945
             L+I  V  E DSG YK +A NS G +   A + + +   +   ++ H +++ + ++   
Sbjct: 3427 SLIIDRV-KEKDSGSYKVMAINSEGSAESTASLLVSMREEQSANYLSHARRAAKAQDSTA 3485

Query: 946  VILE 949
               E
Sbjct: 3486 TSAE 3489



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 24/83 (28%), Positives = 38/83 (45%)

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K +VG+    T    G P P V W K+G+ L N+ +++I  +   S + +      H   
Sbjct: 4361 KARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDRANRSKLTVFYPTADHEGT 4420

Query: 1643 YTIEASNTAGTSSVEVTLKVYDK 1665
            Y    +N  G S    TL++ DK
Sbjct: 4421 YDCIITNKHGKSLCSATLEIADK 4443



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 510  PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P FV KL        G + + EC+  G P     WF+    I P   + M  DD  VA+L
Sbjct: 7588 PTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADD-LVASL 7646

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
             I +    ++G + CVA + AG       + V+AP S
Sbjct: 7647 EIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPS 7683



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 51/244 (20%), Positives = 87/244 (35%), Gaps = 22/244 (9%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561
            +E+   P F +KL            FEC++   G P   + W      ++ +   +M  +
Sbjct: 1427 KEKQQKPQFKKKLTSIRMKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMV-N 1485

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--------EAPLSD------H 607
            +    +L     +  D+G  TC A N  G   ++  LIV        E  L +       
Sbjct: 1486 EFGYCSLDYEVAYARDSGVITCRATNNFGIDQTSATLIVKDEKGLIEETQLPEGRRAPQR 1545

Query: 608  GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667
              E+               +  E   P     P+   V EG      CR+   P P + W
Sbjct: 1546 MEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNW 1605

Query: 668  LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
               G+ I   +   +  +    +Y   L+I ++K +  G   VVA N  G     + L++
Sbjct: 1606 YLNGQLIRKSKRYRLHYDG---IY--YLEIVDIKSYDSGEVRVVADNPLGTTEHTVKLEV 1660

Query: 728  KTGE 731
            +  E
Sbjct: 1661 QQKE 1664



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 2/95 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+FV K  P     G    F+C + G     + W +    I     + M   D N  +L 
Sbjct: 6933 PVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVM-KSDKNKYSLH 6991

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
            I+ +     G + C A N+ G A+ +TEL +++ P
Sbjct: 6992 IQSLELAHQGVYLCKASNSVGTATFSTELWVIDKP 7026



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 60/298 (20%), Positives = 114/298 (38%), Gaps = 32/298 (10%)

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            VA++   E    + +++  GE   P  ++   +  + +G SV+   QV GNP+P + W K
Sbjct: 716  VALSVAVETKEQVTVEVSAGETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKK 775

Query: 771  NNKPVKA---LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            N  P+            +T    + +      D G Y +  +N  G    SA + +EE T
Sbjct: 776  NGLPLTTGYRYRVAYKRETGECKLEISMTFADDAGEYAIFVKNPHGEVSASASL-LEEGT 834

Query: 827  ----------------EENAEPPLFINRFQEITVKEKGTIK--LVARVTRNPVPSITWYR 868
                            + +    +F  +++    +   T K  +   V + P   +T   
Sbjct: 835  GTVLLSSGCHRPWLRGQGSTSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQME 894

Query: 869  NNEIISPSETITQN--FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
              +I +P   +++         E +I  ++  I    Y+ + +         A    + E
Sbjct: 895  QKQITTPVSVVSEREFLISAFEERIIQEIELRIMRITYRELVTEDRELMVTAAEG--EAE 952

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REIIQEGR 980
            +  F   + K+Y   EG  V   C+ S     K  W+ + + +   DH   E +Q+GR
Sbjct: 953  QPAFNTPV-KNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGR 1009



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 29/98 (29%), Positives = 38/98 (38%), Gaps = 6/98 (6%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXXX 1535
            +P   K +  +     E  E TC F G P P VTW +DG  L T    ++     NR   
Sbjct: 4350 APVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPL-TNNPDFDIIDRANRSKL 4408

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
                        Y CI  N HG+   S  + I  K V+
Sbjct: 4409 TVFYPTADHEGTYDCIITNKHGKSLCSATLEIADKIVV 4446



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F  K+       GS+ +F C+V   P     W++    IK S+ +++     + A  +
Sbjct: 6838 PVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALEL 6897

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +  V   D+G ++C   N  G  +    LIV
Sbjct: 6898 VSPV-KADSGEYSCKVSNPHGVDTCAASLIV 6927



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 496  PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555
            P    P   + ++   F+E+ +     + ST  F  +V G P P + W +          
Sbjct: 9788 PAVAAPVKRQDNL--FFIEEPKAVRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGG 9845

Query: 556  FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
                      A L IREV   D+G + C+A N  G    +++L+VE
Sbjct: 9846 RISVDQKGQEAKLEIREVTRSDSGQYRCIASNKHGEIECSSDLLVE 9891



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 87/445 (19%), Positives = 172/445 (38%), Gaps = 65/445 (14%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            +PP +I  L+N  V +G   T E ++  +   ++ WF++  +I+ S     +      +L
Sbjct: 590  VPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARL 649

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
             I +   +D+       G   CTA  T E  +I+              T  YL V++ +E
Sbjct: 650  VIREAFAEDS-------GRFSCTA--TNEAGTIS--------------TSCYLLVKVSEE 686

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
                  Y+++ V E TE    ++  K    +I+            V ++ K    ++V  
Sbjct: 687  IE----YREEPVAEVTE--VGVTQEKICWCLIKHWVA------LSVAVETKEQVTVEVSA 734

Query: 1284 VEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DS 1340
             E   P  +      ++  G  V         P+P+  W  N   +      + +   ++
Sbjct: 735  GETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRET 794

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-------PSPPGKPNILEID 1393
                L I      DAG Y + ++N   H +V  + ++L++        S   +P +    
Sbjct: 795  GECKLEISMTFADDAGEYAIFVKNP--HGEVSASASLLEEGTGTVLLSSGCHRPWLRGQG 852

Query: 1394 SSSINICWDEPEN-------TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
            S+S ++  ++ E        T  + +   V++   +  T+ +  K IT T  S+ + +  
Sbjct: 853  STSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQ-MEQKQIT-TPVSVVSEREF 910

Query: 1447 SSYRFRAYAVNEVDISD--------ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
                F    + E+++           +E  E      E + + P    P+KN        
Sbjct: 911  LISAFEERIIQEIELRIMRITYRELVTEDRELMVTAAEGEAEQPAFNTPVKNYRIMEGMG 970

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523
            +   C   G P PK+ W++DG++L+
Sbjct: 971  VTFHCRMSGKPLPKIAWFKDGQRLR 995



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 31/125 (24%), Positives = 50/125 (40%)

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            A ST +L V V   PP  V   +   +++GS V L V     P P  ++      I+   
Sbjct: 89   ATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPSPTVKFYREGAEIQSSA 148

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
              +   D    SL I +    D+G Y +   N+ G A     + +  + + P K     +
Sbjct: 149  DFQILQDGDLYSLLIAEAFPEDSGTYSVTAANSSGRATSTAELLVQGEEAMPTKKTKTVV 208

Query: 1393 DSSSI 1397
             +S I
Sbjct: 209  STSEI 213



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P+V WYK   +++  +    I+  + +  + +K LK+  S  Y   ASNT G +
Sbjct: 5750 VSGDPVPDVKWYKGAFQVQPGRNCVIISNPDGSGCLSLKSLKQEDSGMYMCRASNTFGEA 5809

Query: 1655 SVEVTLKVY 1663
            S    L V+
Sbjct: 5810 SSSAELAVF 5818



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/94 (26%), Positives = 41/94 (43%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F +++       G+TV+ +  V+G     + W + +  ++          D+NVA L 
Sbjct: 7212 PSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLS 7271

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I  V     G + C A+N AG   S   L V+ P
Sbjct: 7272 IATVAISHGGKYVCQAENEAGQQKSEATLTVQEP 7305



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  +EK    +   GS V F   + G P   I WF+    I  S D  +  D+ +  +L 
Sbjct: 8057 PCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTS-TSLA 8115

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +      D+G + C  +N  G  S    L V+ P
Sbjct: 8116 LFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEP 8149



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 3/99 (3%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            SE     P F +   P     G  V   C++ G    Q+TWF+    +  S+ ++M  + 
Sbjct: 8729 SEAAVEPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEG 8788

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             +V TL I  +   D G + C   N+ G  S T + +V+
Sbjct: 8789 SSV-TLHIIGLESTDIGQYECKVSNSVG--SDTCQTLVK 8824



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 25/102 (24%), Positives = 53/102 (51%), Gaps = 4/102 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+   +   I G P P ++W++   ++E+  +++ +  +  + + I+E     S +++  
Sbjct: 606  GESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFSCT 665

Query: 1647 ASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            A+N AGT  +S  + +KV ++    E PV   E++   VT E
Sbjct: 666  ATNEAGTISTSCYLLVKVSEEIEYREEPV--AEVTEVGVTQE 705



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G P P+V WY NG  +   K Y +   +    + I ++K   S +  + A N  GT+ 
Sbjct: 1595 VTGYPAPKVNWYLNGQLIRKSKRYRL-HYDGIYYLEIVDIKSYDSGEVRVVADNPLGTTE 1653

Query: 1656 VEVTLKVYDK 1665
              V L+V  K
Sbjct: 1654 HTVKLEVQQK 1663



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 19/91 (20%), Positives = 46/91 (50%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G  P +V W+K+   L   ++Y + ++  +  + I  L+ +   +Y  + SN+ G+ +
Sbjct: 8759 LAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTLHIIGLESTDIGQYECKVSNSVGSDT 8818

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             +  +K+ + PS  +    M  +  + VT++
Sbjct: 8819 CQTLVKLREPPSFVKKLSNMTVVLGQEVTLQ 8849



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/94 (27%), Positives = 37/94 (39%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV   +      GS V F   V+G    ++ WFR    ++P +         N   L 
Sbjct: 9112 PSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLE 9171

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +  V    AG +TC   N AG  S    L ++ P
Sbjct: 9172 LFNVDRSHAGEYTCQIINDAGKESWPVNLSIKEP 9205



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F  K   +    GSTV F     G     + WF++   I     + +  D  + ++L 
Sbjct: 7495 PTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATS-SSLE 7553

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            ++ V P D+  + C   N AG    T  L V+ P
Sbjct: 7554 LQAVKPSDSARYACQVSNDAGKVDCTALLFVKEP 7587



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 2/78 (2%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQL-TIDGKKQKLK 1164
            P   T ++N ++ +G   TF   ++ K    + WFKDG  ++ S+H Q+ T+   +  L+
Sbjct: 954  PAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLR 1013

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            +     +D G Y+    N
Sbjct: 1014 LAQVLPEDEGVYTAFAAN 1031



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 1/50 (2%)

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKY 1063
            T P+F+ KL++  VKE  +  L V+ I +   D+VW ++ +II P K+ +
Sbjct: 1258 TRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISPHKHPH 1307



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 18/58 (31%), Positives = 28/58 (48%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            + E    P FVEKL+     +G+ V+   +  G P P I W + + II P +   + Y
Sbjct: 1253 ARESLTRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISPHKHPHIKY 1310



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK----SASLTIKKVENTD 1354
            +  G  V L  +  A P P+  W  N+K + K +  +   DS+    + SL I +V+  D
Sbjct: 3378 VLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTTSLIIDRVKEKD 3437

Query: 1355 AGIYKLRLENNCGHAD 1370
            +G YK+   N+ G A+
Sbjct: 3438 SGSYKVMAINSEGSAE 3453



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            P  +V+W K+G +L+  +E  +TT EK    + I+ ++ S + +Y++ A ++   S  ++
Sbjct: 2838 PNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSS--VSKAQL 2895

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             ++  D    P     +  + +   TIE++   DD
Sbjct: 2896 VVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDD 2930



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 540  QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE-DAGTFTCVAKNAAGFASSTTEL 598
            ++ W     ++KP ++F+   + D   TLVI +V  E   G + C A+N AG  ++++ L
Sbjct: 6772 KVNWLFNGQLVKPGKEFRCSKEKDTY-TLVISKVVKEMHQGEYVCEAENEAGKTTTSSRL 6830

Query: 599  IV 600
             V
Sbjct: 6831 TV 6832


>UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus
            musculus (Mouse)
          Length = 8268

 Score =  266 bits (653), Expect = 3e-69
 Identities = 273/1226 (22%), Positives = 500/1226 (40%), Gaps = 97/1226 (7%)

Query: 469  VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
            +P+  + D+  YT  ++ ++ +    + V       ++ + P FV +L+      G++V 
Sbjct: 3365 IPSAEMNDKGLYTFEVENRVGKSSCTVSVHVS----DRVVPPSFVRRLKDTSATLGASVV 3420

Query: 529  FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
             EC+V G     + WF     I  S   Q  + D NV TL +  + P D G +TCVA N 
Sbjct: 3421 LECRVSGSAPISVGWFLDGNEIISSPKCQSSFAD-NVCTLTLSSLEPSDTGAYTCVAANV 3479

Query: 589  AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
            AG   S+  L V+ P S   +  +V             ++L G+  TF+       V  G
Sbjct: 3480 AGQDESSAVLTVQEPPSFEQTPDSV-------------EVLPGMSLTFTS------VIRG 3520

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
            +           P   + W     E+V  E  ++++E     + + L++  V+  Q G Y
Sbjct: 3521 T-----------PPFKVKWFKGSRELVSGEACTISLED----FVTELELLEVEPGQSGDY 3565

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
            + +  N  G AS    L +    KEP   ++ L    V  G  ++L A   G P  +++W
Sbjct: 3566 SCLVTNDAGSASCTTHLFV----KEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSW 3621

Query: 769  CKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
             KN  P+   P      T   +IL+     ++D   Y    EN  G     A+++V    
Sbjct: 3622 MKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSV---- 3677

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                EPP FI   + +       I L  +V   P   I+WY+ +  +  +      F   
Sbjct: 3678 ---LEPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNN 3734

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGK 944
               LVI  VD   D G+Y C A NS G  +  A + I   K+  +F + L+  +ET  G 
Sbjct: 3735 VASLVINKVDHS-DVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHET-LGF 3792

Query: 945  TVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
             V  EC+   S  +   WY + + +    + ++                  VG   C   
Sbjct: 3793 PVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSAS 3852

Query: 1003 D----QETSTMLVVKE-TIPEFI-RKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEI 1055
            +      +S  L++ E  +P F   K    ++   +    +  +  +    + W +D   
Sbjct: 3853 NPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNRE 3912

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIIT 1111
            I+P  N Y      +   L +   +  D G+Y+C    +   +SC+A++ V E PP  I 
Sbjct: 3913 IRPGGN-YKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQE-PPRFIK 3970

Query: 1112 RLQNQKVNKGNKAT-FEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
            +L   ++ K ++ T +E ++     + V W+KD  EIQ S+  +++ +     L+++   
Sbjct: 3971 KLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLS 4030

Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DET 1224
            ++D+G+Y+CE     G++  +  L V+EP +      P   L  A  D +L  E+     
Sbjct: 4031 VEDSGDYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVETLKGA--DVHLECELQGTPP 4088

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEV 1283
              V+W+K K  +   +K+ ++S+    ++ I      D  EY C    D  S T +    
Sbjct: 4089 FQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVT 4148

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342
            ++ PP+ V    +     G +V L    +     +  W  +  +I+++  +   S     
Sbjct: 4149 MKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENI 4208

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            A+L   + E  +AG Y  +++N+ G  +    +++L+  +   KP  +++ +   + C  
Sbjct: 4209 ATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEPAAIVEKPESIKVTTG--DTCTL 4266

Query: 1403 EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVD 1460
            E   +G   +   +  + +E+ +     +    K     I N+    S  +     N V 
Sbjct: 4267 ECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNPVG 4326

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
              D+ + +    +    +I  P+  + LK         + + C   G P   V W+ DG 
Sbjct: 4327 -KDSCKVS----IQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGN 4381

Query: 1521 KLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            ++ + +       +N                Y CIA N  G  E S  + +++ P   + 
Sbjct: 4382 EISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSF-VQ 4440

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
              D       G     T++++G PP  V W+K   +L      N++ ++    + + ++ 
Sbjct: 4441 KPD-PMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVD 4499

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKV 1662
             S S +YT   SN AG +S    L V
Sbjct: 4500 TSQSGEYTCIVSNEAGRASCTTRLFV 4525



 Score =  258 bits (632), Expect = 1e-66
 Identities = 244/1080 (22%), Positives = 443/1080 (41%), Gaps = 53/1080 (4%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F KK +A     G     +  L       + WL   +EI  D+NI +  E+++    
Sbjct: 1146 PPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNV---- 1201

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L ++ ++   +G Y   A N  G      +L +K    EP  ++E   S+ V QG+  
Sbjct: 1202 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK----EPATIMEEAVSIDVTQGDPA 1257

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810
             L  +  G    +  W K+ + +   P      T +++ILK    + KD G YT + +N 
Sbjct: 1258 TLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQND 1317

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G +   A I V +       PP F  + +++   +   I L   V  +   SI W++++
Sbjct: 1318 VGRSSCKASINVLDLII----PPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDD 1373

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            + IS S+    +F      L I+ ++   DSG Y C A+N AG S     +T+  E   F
Sbjct: 1374 QEISASDKHKFSFHDNTAFLEISQLEGT-DSGTYTCSATNKAGHSQCSGHLTVK-EPPYF 1431

Query: 931  VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            V+  Q S +   G  V L+     T  ++ KW+ + KE+     R + ++          
Sbjct: 1432 VEKPQ-SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFS 1490

Query: 989  XXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEV-KEKDVAILEVEIN-S 1042
                D G   C + +   +T     + VKE  P+FI+K     V +       E ++  +
Sbjct: 1491 AKAADSGTYICQLSNDVGTTSSKATIFVKEP-PQFIKKPSPVLVLRNGQSTTFECQVTGT 1549

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
                V W  DG  I   + KY       +    I N  V + G Y C  R+++ TA  ++
Sbjct: 1550 PEIRVSWYLDGNEITDLR-KYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSI 1608

Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDG 1158
               V+ PP  I  L+  +V K +    E E+       V W K+  EI+      ++   
Sbjct: 1609 ELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKM 1668

Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
                L I  CD  D GEY C    E G+  C+A + ++EP  +F  ++     V  ++  
Sbjct: 1669 SVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPP-SFIKKIENVTTVLKSSAT 1727

Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
            + +       + +TW K   ++E+ +   +  +    TL +R         YTC   +  
Sbjct: 1728 FQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNES 1787

Query: 1275 STTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
               +    + V+ P +I++  +   +     VTL       P+   +W+ + K I   ++
Sbjct: 1788 GIERCYAFLLVQEPAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRY 1847

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNILEI 1392
               S ++  AS  I+ V   D+G Y  ++EN+ G +  +  + +LD+  PP     + ++
Sbjct: 1848 FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKM 1907

Query: 1393 DSSSINICWDEPENTGNSTI-IYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYR 1450
            D    +    E + +G+  I   +  + +EI T+ ++  V +       + NL+   +  
Sbjct: 1908 DKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTAN 1967

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +     N    +  S        I   K     + KP +     P+  +E   +  G P 
Sbjct: 1968 YTCKVSNVAGDNACSG-------ILTVKEPPSFLVKPERQQAI-PDSTVEFKAVLKGTPP 2019

Query: 1511 PKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
             K+ W +D  +L +    +     +                Y C   ND G    + ++ 
Sbjct: 2020 FKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDSSKTGQYTCQVTNDVGSDSCTTMLL 2079

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
            + + P   +   +  +  K GD   +   I G P  +V+WY+N ++L    +Y +T  + 
Sbjct: 2080 VTEPPKF-VKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDS 2138

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             +VI++  L    S  +  EA N AG++S    + V + P     P I+  +    V++E
Sbjct: 2139 VAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNTEVSLE 2198



 Score =  257 bits (630), Expect = 2e-66
 Identities = 267/1184 (22%), Positives = 466/1184 (39%), Gaps = 67/1184 (5%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  V  L+   T +G   +F+CQV G    +++W+ +   IKPS+ F+M   +D    L 
Sbjct: 6    PAIVTPLQDTVTSEGRPARFQCQVSGTDL-KVSWYCKDKKIKPSRFFRMTQFEDTYQ-LE 63

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I E +PED GT+  VA NA G  SST  L +EAP S                     ++ 
Sbjct: 64   IAEAYPEDEGTYAFVANNAVGQVSSTATLRLEAPES-----------ILHERIGQQIEME 112

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
                P   ++ +   V  G      C +   P     W   G EI   +  S+   +   
Sbjct: 113  MKAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSN--- 169

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             Y S L+I   +    G YT  A N  G  S    L +   E  PP  +   K++    G
Sbjct: 170  -YVSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT--EAYPPTFLSRPKALTTFVG 226

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807
            ++      V G P   I W K+   +   P    +D D      L    V+D G+Y+ KA
Sbjct: 227  KAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKA 286

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G     A +T+        + P FI   + +       I L  +V  +   +ITW 
Sbjct: 287  SNKFGADICQAELTI-------IDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWS 339

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++ + +   +     F+ +   L I     + DSG Y C ASN AG SS  A V +  E 
Sbjct: 340  KDGQKLPAGKDYKIYFEDKIASLEIPLAKLK-DSGTYTCTASNEAGSSSSSAAVAVR-EP 397

Query: 928  VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             +FVK +  SY    G++  L C+   S  +   W+ N KE+S  +   +          
Sbjct: 398  PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILD 457

Query: 986  XXXXXXXDVGVIKC----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI- 1040
                   D G   C     V     ST +V+KE  P FI+ L+  ++     A+L+ EI 
Sbjct: 458  ITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKEP-PSFIKTLEPADIVRGANALLQCEIA 516

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTA 1098
             +   +V W +D + I+  K KY    +     L I + +  D G+Y C++ +E   C  
Sbjct: 517  GTGPFEVNWFKDKKQIRSSK-KYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGC 575

Query: 1099 EVT-VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156
              T +++ PP  + ++ +     G   T +  +   + + V W K    I+    I+++ 
Sbjct: 576  VATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSF 635

Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
                  L I D  +   G+Y+C    E G+      L V+EP+    +   E I V A  
Sbjct: 636  SNGVAVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPA--KIIERAELIQVTAGD 693

Query: 1213 DAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
             A L   +     L   WYK    +  ++K+ +        L        D  +YT  + 
Sbjct: 694  PATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEIS 753

Query: 1272 D----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            +    +   T   V   +  P      R      G    L             W  + K 
Sbjct: 754  NEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKE 813

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +      + +    +ASL I +V+  DAG +  R  N+ G  D    + + + PS   KP
Sbjct: 814  LTASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKP 873

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
               ++   S        + +   TI ++  + + +        K  +++   +  +KT+ 
Sbjct: 874  GSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSD 933

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            S  +     N     + S        +KE    +  +EK   +   +  +  +L C   G
Sbjct: 934  SGTYTCKVSNVAGSVECSADL----FVKE---PATFIEKLEPSQLLKKGDGTQLACKVTG 986

Query: 1508 VPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
             P  K+TW+ + ++L+ +   K ++ E+                Y C A N+ G    + 
Sbjct: 987  TPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTG 1046

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
            +V +++ P  T   + I+   +   + ++ A + G PP E+ W+K+   L + ++Y    
Sbjct: 1047 IVIVKESPYFTKEFKSIEVLKEY--DVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFL 1104

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +++   +++ +   + + +Y    +N  G+S+    + + + PS
Sbjct: 1105 QDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPS 1148



 Score =  254 bits (621), Expect = 3e-65
 Identities = 252/1096 (22%), Positives = 449/1096 (40%), Gaps = 74/1096 (6%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            + E  PPTF  +PKA     G      C +   P  +I W   G  + P  +  V    +
Sbjct: 206  VTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADN 265

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             H     L+++N+     G Y+  A N+ G       L I     + P  I+ L+++   
Sbjct: 266  KHS----LELSNLTVQDRGIYSCKASNKFGADICQAELTI----IDKPHFIKELEAVQSA 317

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK-P-KKVKDEGVYTL 805
              + + L  QV  + + TITW K+ + + A           I  L+ P  K+KD G YT 
Sbjct: 318  INKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTC 377

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSI 864
             A N  G + +SA + V        EPP F+ +     +   G + +L  ++  +PV  +
Sbjct: 378  TASNEAGSSSSSAAVAVR-------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV 430

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TW++NN+ +S S T+  +F      L IT+V  + DSG Y C A+N  G  S    V I 
Sbjct: 431  TWFKNNKELSESNTVRMSFVNSEAILDITDVKVD-DSGTYSCEATNDVGSDSCSTEVVIK 489

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXX 982
             E  +F+K L+ + +   G   +L+C+ + T      W+ +KK+I       +  +    
Sbjct: 490  -EPPSFIKTLEPA-DIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKKYRLFTQKTFV 547

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVE 1039
                      DVG  +C+V ++      V    +   P F++K+ DF         L+  
Sbjct: 548  YLEISSFNSADVGDYECVVANEVGKCGCVATHLLKEPPTFVKKVDDFTALAGQTVTLQAA 607

Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--- 1095
            +  SE   V+W +  E+IK +  K        +  L I +  +   G+Y+C+  +E+   
Sbjct: 608  VRGSEPISVMWMKGQEVIK-EDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQ 666

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
             +    +V+ P +II R +  +V  G+ AT E  ++    L  +W+KDG  +  S   ++
Sbjct: 667  TSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRI 726

Query: 1155 TIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSIN--FT--LRLPEFI 1206
            +      +LK Y  +L D+G+Y    S EVG+S C    TV +  I   FT  LR  + +
Sbjct: 727  SFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSV 786

Query: 1207 LVPA-NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
            +  A   D  +   +P   + V+W+K    +  ++++ +       +L I +   +D   
Sbjct: 787  VGGACRLDCKIAGSLP---MRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGN 843

Query: 1266 YTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
            +TC   ++  S       +V+ PP  V       +  GS V L   +Q       +W   
Sbjct: 844  FTCRATNSVGSKDSSGALIVQEPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKG 903

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTIL 1378
             K +        + ++  +SL +  V+ +D+G Y  ++ N  G  +      V+   T +
Sbjct: 904  DKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSVECSADLFVKEPATFI 963

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ 1437
            +K  P     +L+    +   C    + TG   I I +    +E+  +    +     T 
Sbjct: 964  EKLEP---SQLLKKGDGTQLAC----KVTGTPPIKITWFANDRELRESSKHKMSFAESTA 1016

Query: 1438 T-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               + ++    S  +   A NE      S+      ++KE    SP   K  K+I     
Sbjct: 1017 VLRLTDVAIEDSGEYMCEAQNEA----GSDHCTGIVIVKE----SPYFTKEFKSIEVLKE 1068

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXXXXXXXXXXXXXXXYKCIA 1552
             D+ L     G P  ++TW++D   L++ +   T+  +                 Y+C  
Sbjct: 1069 YDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVAADAGEYQCRV 1128

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             N+ G    S  V +++ P      E        G      A ++G  P  V W K+ ++
Sbjct: 1129 TNEVGSSTCSARVTLREPPSFIKKIEATSSLR--GGTAAFQATLKGSLPITVTWLKDNDE 1186

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            +  D    +T +   + + +  ++  H  KY  +A N AG       L V +  +  E  
Sbjct: 1187 ITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIMEEA 1246

Query: 1673 VIMREISRESVTIEWK 1688
            V +     +  T++ K
Sbjct: 1247 VSIDVTQGDPATLQVK 1262



 Score =  253 bits (620), Expect = 3e-65
 Identities = 292/1267 (23%), Positives = 489/1267 (38%), Gaps = 72/1267 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P TF KK     V+ G  I+LE          + W   G  I P E  ++         C
Sbjct: 2646 PATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKT---C 2702

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             +L+I +  K   G Y+    N  G  +   ++       EPP  +  L+ +    G+SV
Sbjct: 2703 -ILEILSSTKGDAGHYSCEIENEAGRDACDALVSTL----EPPYFVTELEPLEASVGDSV 2757

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
             L  QV G P  T++W K +  +++ P      T+++  L   KV   D G YT  AENS
Sbjct: 2758 SLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENS 2817

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G A +  +  ++E       PP F  + ++I       + L  R+  +    + WYR+ 
Sbjct: 2818 IGTAASKTIFRIQE----RQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG 2873

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT 929
             ++   E +  +F      L I   D    SG Y C ASN  G +S  AR+T  + +K  
Sbjct: 2874 VLLRDDENLQMSFVDNVATLKILQTDLS-HSGQYSCSASNPLGTASSTARLTAREPKKSP 2932

Query: 930  FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            F      S +   G++   EC  +    +   W  + KEI    +  I   G        
Sbjct: 2933 FFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRIL 2992

Query: 988  XXXXXDVGVIKC-----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-LEVEIN 1041
                 D G   C     + KD   S  L VKE  P+FI+KL   +V ++  +I LE +I+
Sbjct: 2993 KVGKGDSGQYTCQATNDVGKDM-CSAQLSVKEP-PKFIKKLDASKVAKQGESIQLECKIS 3050

Query: 1042 -SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESC 1096
             S    VVW R+   +  +  KY+      +  L I   S  D G+Y C       D SC
Sbjct: 3051 GSPEIKVVWFRNDSELH-ESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASC 3109

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
            +  + V + PP    +       KG+    + E++      V W KD  +++ S   ++T
Sbjct: 3110 STALKV-KAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKIT 3168

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
                   L I++ +  D GEY C    EVG+  C   +  +EP   F  +L +   +  +
Sbjct: 3169 SKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPP-RFVKKLSDASTLIGD 3227

Query: 1212 TDAYLTVEIPDETLDVTWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                  V    + + V W K K  VI ++E   +       TL +         +Y C +
Sbjct: 3228 PVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQI 3287

Query: 1271 L-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
              DA       V  V  P  IV+      +  G+  TL       P+ + +W  + + + 
Sbjct: 3288 KNDAGMRECSAVLTVLEPATIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELS 3347

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
                   +     ASL I   E  D G+Y   +EN  G +   ++V + D+  PP     
Sbjct: 3348 SGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRR 3407

Query: 1390 LEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446
            L+  S+++      E   +G++ I + + ++  EI ++            T ++ +L+ +
Sbjct: 3408 LKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPS 3467

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
             +  +   A N     ++S           T  + P+ E+   ++   P   +  T +  
Sbjct: 3468 DTGAYTCVAANVAGQDESSAVL--------TVQEPPSFEQTPDSVEVLPGMSLTFTSVIR 3519

Query: 1507 GVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETS 1562
            G P  KV W++  ++L + +A   + E+                 Y C+  ND G    S
Sbjct: 3520 GTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSA--S 3577

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
            C   +  K   T          + G   ++ A   G PP  V W KN   L       IT
Sbjct: 3578 CTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGIT 3637

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
            T EK+S++ I E      ++Y     N AG    E  + V + P   E    +     E 
Sbjct: 3638 TTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAIGEP 3697

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            +T++ K    DG  E+     ++H    +          +V +  I K++ +    +   
Sbjct: 3698 ITLQCKV---DGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCK 3754

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP--II 1800
            A+N VG      S  +VIK     PS          +     +   F    NG  P  + 
Sbjct: 3755 AENSVG--AVASSAVLVIKERKLPPS---FARKLKDVHETLGFPVAFECRINGSEPLQVS 3809

Query: 1801 DYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
             YK  E+ ++    +          +I +   +   Q+   A N +GT+   +S  K+ +
Sbjct: 3810 WYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTA---SSSAKLIL 3866

Query: 1860 GKTLTPP 1866
             +   PP
Sbjct: 3867 SEHEVPP 3873



 Score =  252 bits (618), Expect = 6e-65
 Identities = 290/1262 (22%), Positives = 515/1262 (40%), Gaps = 82/1262 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+F+++ K      G  + L CRL       + W   G  +  DEN+ ++   ++   
Sbjct: 2834 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNV--- 2890

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + LKI        G Y+  A N  G AS    L  +  +K P   I+P+ S+ V  GES
Sbjct: 2891 -ATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPV-SIDVIAGES 2948

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
                  V G     +TW K+NK ++          G+T  + ILK  K  D G YT +A 
Sbjct: 2949 ADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK-GDSGQYTCQAT 3007

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867
            N  G    SA ++V+       EPP FI +     V ++G +I+L  +++ +P   + W+
Sbjct: 3008 NDVGKDMCSAQLSVK-------EPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWF 3060

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            RN+  +  S     +F   ++ L+  N  S  D+GDY C A N  G +S    + +    
Sbjct: 3061 RNDSELHESWKYNMSF-VNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPP 3119

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            V   K         +G  VIL+C+ S T      W  ++K++      +I  +       
Sbjct: 3120 VFTQK--PPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLH 3177

Query: 986  XXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                   D+G   C   ++   +T    V  +  P F++KL D      D   L+  +  
Sbjct: 3178 IFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDASTLIGDPVELQAVVEG 3237

Query: 1043 -ETADVVWERD-GEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---- 1095
             +   VVW +D GE+I+  +N +  F    +I  L + +      G+Y C +++++    
Sbjct: 3238 FQPISVVWLKDKGEVIRESENVRISFV--DNIATLQLGSPEASQSGKYVCQIKNDAGMRE 3295

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
            C+A +TV+E P  I+ + +   V  GN  T E  +     L  +WFKDG E+   +   +
Sbjct: 3296 CSAVLTVLE-PATIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHI 3354

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSI--NFTLRLPEFILV 1208
            T       LKI   +++D G Y+ E    VG S CT  + V +  +  +F  RL +    
Sbjct: 3355 TFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKD---T 3411

Query: 1209 PANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
             A   A + +E        + V W+   + I  + K          TL +      D   
Sbjct: 3412 SATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPSDTGA 3471

Query: 1266 YTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
            YTCV  + A       V  V+ PP          +  G  +T     +  P    +W   
Sbjct: 3472 YTCVAANVAGQDESSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKG 3531

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
            S+ +   +    S++     L + +VE   +G Y   + N+ G A    ++ + +  +  
Sbjct: 3532 SRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKEPATFV 3591

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNL 1443
             +     +++ S  +       T   ++ +   EY    +        IT T+ +SI  +
Sbjct: 3592 KRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNC----GITTTEKSSILEI 3647

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
              ++   +  YA   ++     +  E    +    ++ P   +PL+++     E I L C
Sbjct: 3648 LESTIEDYAQYAC-LIENEAGQDICEALVSV----LEPPYFIEPLEHVEAAIGEPITLQC 3702

Query: 1504 IFGGVPQPKVTWYRDGKKLKTA---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
               G P+ +++WY++  KL++A   K  ++N                 Y C A N  G V
Sbjct: 3703 KVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAV 3762

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             +S V+ I+++ +       +K  H+ +G        I G  P +V WYK+G  L++D  
Sbjct: 3763 ASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDAN 3822

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLKVYDKPSKPE-GPVIM 1675
              ++     + ++I +  +SH  +Y   ASN  GT  SS ++ L  ++ P   +  PV +
Sbjct: 3823 LQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSV 3882

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
                 ES + +         +++T +A +  E       K+  V+ +  T  + K+ +  
Sbjct: 3883 DLALGESGSFKCH-VTGTAPIKIT-WAKDNREIRPGGNYKMTLVE-NTATLTVLKVAKGD 3939

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
               +   A N  G       +    +  +  P           I  +  Y  +    K G
Sbjct: 3940 AGQYTCYASNVAG------KDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRY--ECKIG 3991

Query: 1796 GSP---IIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851
            GSP   ++ YK E++ QE  K++           +  LS+  +  +   ARN  G++   
Sbjct: 3992 GSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSS 4051

Query: 1852 TS 1853
            TS
Sbjct: 4052 TS 4053



 Score =  252 bits (617), Expect = 8e-65
 Identities = 257/1083 (23%), Positives = 427/1083 (39%), Gaps = 61/1083 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P    +K  +  V  G    LEC++   PE  + W   G+ +   +    +  + +    
Sbjct: 2364 PAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI---- 2419

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            S LKI +V+K   GTYT    N  G++S   V+ + +    PP     LK      G S 
Sbjct: 2420 SSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDV-SDRMVPPSFTRRLKDTGGVLGTSC 2478

Query: 753  ILSAQVVGNPRPTITWC-KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810
            IL  +V G+   +I W  +  K V     ++    +  T+ L      D G YT  A N 
Sbjct: 2479 ILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANV 2538

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G  E  A++TV+EP       P F+   + + V     I   + +   P   + W+R  
Sbjct: 2539 AGSDECRALLTVQEP-------PSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGA 2591

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +         F+    EL + N+D    SG+Y CV SN+AG++S   R+ +  E  TF
Sbjct: 2592 RELVKGNRCNIYFEDTVAELELFNIDIS-QSGEYTCVVSNNAGQASCTTRLFVK-EPATF 2649

Query: 931  VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            VK L   +  E GK++ILE   + T  +S  W  +   I+  +   I+   +        
Sbjct: 2650 VKKLS-DHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILS 2708

Query: 989  XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSET 1044
                D G   C ++++   +    LV     P F+ +L+  E    D   L+ ++  +  
Sbjct: 2709 STKGDAGHYSCEIENEAGRDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPE 2768

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV- 1103
              V W + G+       +Y      ++  L     S++D GEY+C+  +   TA    + 
Sbjct: 2769 ITVSWFK-GDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIF 2827

Query: 1104 -----ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID 1157
                 +LPP    +L++ +   G   T    L     + V W++DG  ++   ++Q++  
Sbjct: 2828 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFV 2887

Query: 1158 GKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN--FTLRLPEFILVPAN 1211
                 LKI   DL  +G+YSC     +G +  TA LT  EP  +  F ++ P  I V A 
Sbjct: 2888 DNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIK-PVSIDVIAG 2946

Query: 1212 TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              A     +   + + VTW K    I     +T+        L I K  + D  +YTC  
Sbjct: 2947 ESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 3006

Query: 1271 LD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
             +   K     ++ V E P  I   +     K+G  + L       P+    W  N   +
Sbjct: 3007 TNDVGKDMCSAQLSVKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSEL 3066

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
             +      S  +  A LTI +    D G Y     N  G A     + +   P    KP 
Sbjct: 3067 HESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKPP 3126

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNS 1447
             +     S  I   E   T    +++     Q   + ++ I+ KN   T   I NL+   
Sbjct: 3127 PVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFD-TSLHIFNLEAPD 3185

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
               +   A NEV  SD    T  +K       + P   K L + +T   + +EL  +  G
Sbjct: 3186 IGEYHCKATNEVG-SDTCACTVKFK-------EPPRFVKKLSDASTLIGDPVELQAVVEG 3237

Query: 1508 VPQPKVTWYRD-GKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
                 V W +D G+ ++ ++    +  +N                Y C   ND G  E S
Sbjct: 3238 FQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQIKNDAGMRECS 3297

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
             V+ + +   I    E +      G+ + +  V+ G P     W+K+G +L +   ++IT
Sbjct: 3298 AVLTVLEPATIVEKPEPMTVT--TGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHIT 3355

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
                 + ++I   + +    YT E  N  G SS  V++ V D+   P     +R +   S
Sbjct: 3356 FVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPS---FVRRLKDTS 3412

Query: 1683 VTI 1685
             T+
Sbjct: 3413 ATL 3415



 Score =  252 bits (616), Expect = 1e-64
 Identities = 279/1212 (23%), Positives = 498/1212 (41%), Gaps = 106/1212 (8%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            VEK  P     G+    EC V G P     WF+    +       + +   N+A+L I  
Sbjct: 3309 VEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVR-NLASLKIPS 3367

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
                D G +T   +N  G +S T        +S H S+  V                   
Sbjct: 3368 AEMNDKGLYTFEVENRVGKSSCT--------VSVHVSDRVV------------------- 3400

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F ++ K      G+ ++LECR+       + W   G EI+       +   ++   C
Sbjct: 3401 PPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNV---C 3457

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L +++++    G YT VA N  G+     VL +    +EPP   +   S+ V  G S+
Sbjct: 3458 T-LTLSSLEPSDTGAYTCVAANVAGQDESSAVLTV----QEPPSFEQTPDSVEVLPGMSL 3512

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
              ++ + G P   + W K ++ + +    +      +T L+  +V+    G Y+    N 
Sbjct: 3513 TFTSVIRGTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTND 3572

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G A  +  + V+EP         F+ R  + +V+    I L A  +  P  S++W +N 
Sbjct: 3573 AGSASCTTHLFVKEPA-------TFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNE 3625

Query: 871  EII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
              +  SP+  IT       +E++ + ++   D   Y C+  N AG+    A V++ +E  
Sbjct: 3626 YPLSQSPNCGITTTEKSSILEILESTIE---DYAQYACLIENEAGQDICEALVSV-LEPP 3681

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             F++ L+   E   G+ + L+C+   T  +   WY    ++      ++  +        
Sbjct: 3682 YFIEPLE-HVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 3740

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040
                  DVG   C  ++      +S +LV+KE    P F RKL+D           E  I
Sbjct: 3741 NKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRI 3800

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            N SE   V W +DGE++K   N        H+  L I  T     G+Y+C   +   TA 
Sbjct: 3801 NGSEPLQVSWYKDGELLKDDAN-LQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTAS 3859

Query: 1100 ------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151
                  ++  E+PP    +  +  +  G   +F+  +T G A ++  W KD  EI+   +
Sbjct: 3860 SSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVT-GTAPIKITWAKDNREIRPGGN 3918

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
             ++T+      L +      DAG+Y+C      G   C+A L V+EP   F  +L +  +
Sbjct: 3919 YKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPP-RFIKKLDQSRI 3977

Query: 1208 VPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            V    D Y   E        + V WYK +  I+++ KF +  +     L +   + +D  
Sbjct: 3978 V--KQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSG 4035

Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            +YTC   +A  +      + V+ PP            +G+DV L  + Q  P     W  
Sbjct: 4036 DYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHK 4095

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            + + ++  K  K   ++   S+ I  V+  D G Y+ +  N+ G      +VT+   P  
Sbjct: 4096 DKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKAPPQF 4155

Query: 1384 PGK-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISV-KNITKTQTS 1439
              K  +I  I    + +     E     ++ ++  + + +  ++  WIS  +NI   Q S
Sbjct: 4156 VKKLTDISTIIGKEVQL-QTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFS 4214

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
                +  ++ ++     N+  + +   T     V++   I    VEKP ++I     +  
Sbjct: 4215 --RAEPANAGKYTCQIKNDAGMQECYAT---LSVLEPAAI----VEKP-ESIKVTTGDTC 4264

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXX-XXXXXYKCIAFND 1555
             L C   G P+    W++DGK+L +    K ++ N+                Y     N 
Sbjct: 4265 TLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNP 4324

Query: 1556 HGEVETSCVVGIQ-QKPVITIS-NEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             G  + SC V IQ    +I  S    +K+ + + G   ++   + G PP  V+W+ +GN+
Sbjct: 4325 VG--KDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNE 4382

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            + + ++Y  T  + T  + +  L+ + +  YT  A+N AG+      L V + PS  + P
Sbjct: 4383 ISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKP 4442

Query: 1673 VIMREISRESVT 1684
              M  ++  +VT
Sbjct: 4443 DPMDVLTGSNVT 4454



 Score =  250 bits (613), Expect = 2e-64
 Identities = 279/1201 (23%), Positives = 480/1201 (39%), Gaps = 96/1201 (7%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+ + P F  KL+  H   G  V FEC++ G    Q++W++   ++K   + QM +   
Sbjct: 3771 KERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSF-VH 3829

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
            +VATL I +      G + C A N  G ASS+ +LI    LS+H                
Sbjct: 3830 HVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLI----LSEH---------------- 3869

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                    +PP F  KP +  +  G     +C +       I W     EI P  N  + 
Sbjct: 3870 -------EVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 3922

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-K 742
            +  +     + L +  V K   G YT  A N  G+ S    L    G +EPP+ I+ L +
Sbjct: 3923 LVEN----TATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQL----GVQEPPRFIKKLDQ 3974

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDE 800
            S IV+Q E      ++ G+P   + W K+   ++       S  D+ +I  +    V+D 
Sbjct: 3975 SRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDS 4034

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            G YT +A N+ G A +S  + V+       EPP+F  +   +   +   + L   +   P
Sbjct: 4035 GDYTCEARNAAGSASSSTSLKVK-------EPPVFRKKPFPVETLKGADVHLECELQGTP 4087

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
               ++W+++   +   +      +     + I NVD+  D G+Y+C A+N  G  +    
Sbjct: 4088 PFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDT-ADIGEYQCKATNDVGSDTCVGS 4146

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEI-SGMDHREIIQ 977
            VT+      FVK L     T  GK V L+   + +  +S  W+ +K EI    D+  I  
Sbjct: 4147 VTMKAPP-QFVKKL-TDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISY 4204

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
                           + G   C +K+    QE    L V E     + K +  +V   D 
Sbjct: 4205 SENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEP-AAIVEKPESIKVTTGDT 4263

Query: 1034 AILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
              LE  ++ +      W +DG+ +    NKY       +  L I N    D G YS  ++
Sbjct: 4264 CTLECTVSGTPELSTKWFKDGKEL-TSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQ 4322

Query: 1093 D----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE 1145
            +    +SC   + V +  +PP    +L+      G+    E ++     + V WF DG+E
Sbjct: 4323 NPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNE 4382

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201
            I      Q T+      L +   +  DAG+Y+C      G+ +C+A LTV EP       
Sbjct: 4383 ISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKP 4442

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
             P  +L  +N   + ++        V+W+K  + +    +  +        L +      
Sbjct: 4443 DPMDVLTGSNV-TFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTS 4501

Query: 1262 DQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
               EYTC++ +    A  TT+L    V+ P   V    +Y I++G  + L   +   P  
Sbjct: 4502 QSGEYTCIVSNEAGRASCTTRL---FVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPI 4558

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            +  W  N   +   +    +   KSA L I      D+G Y   +EN  G       + I
Sbjct: 4559 SVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILI 4618

Query: 1378 LDKPSPPGKPNILEI---DSSSINICWDEPENTGNSTIIYYVVEYQEIDT-TEWISVKNI 1433
            L+ P    +   +++   DS+S+  C  +   T    + +Y  + +   T T  +  KN 
Sbjct: 4619 LEPPYFVKQLEPVKVTVGDSASLQ-C--QLAGTPEIGVSWYKGDTKLRPTATCKMHFKNN 4675

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
              T    Q + ++ S  +   A N V   + S +T  +  ++E K+  P+  + L+++  
Sbjct: 4676 VATLVFTQ-VDSSDSGEYICRAENSV--GEVSSST--FLTVQEQKL-PPSFSRQLRDVQE 4729

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYK 1549
                 +   C   G     V+WY+DGK LK +     +  +N                Y 
Sbjct: 4730 TVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYS 4789

Query: 1550 CIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            C A N  G   +   ++  + K               VG+   +   + G  P +V W K
Sbjct: 4790 CTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAK 4849

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            +  ++ +   Y I+  E ++ + I ++ +  S +YT  A N  G  S    L + ++   
Sbjct: 4850 DNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP 4909

Query: 1669 P 1669
            P
Sbjct: 4910 P 4910



 Score =  248 bits (607), Expect = 1e-63
 Identities = 253/1080 (23%), Positives = 436/1080 (40%), Gaps = 76/1080 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP      +     EG     +C+ V+  +  ++W  K ++I P     +    D +   
Sbjct: 5    PPAIVTPLQDTVTSEGRPARFQCQ-VSGTDLKVSWYCKDKKIKPSRFFRMTQFEDTYQ-- 61

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---------------KEPPQV 737
              L+I       EGTY  VA N  G+ S    L+++  E               K  P +
Sbjct: 62   --LEIAEAYPEDEGTYAFVANNAVGQVSSTATLRLEAPESILHERIGQQIEMEMKAAPVI 119

Query: 738  IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794
               ++ + V  G     + ++ G P     W K  + +        +S     S+ IL+ 
Sbjct: 120  KRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRT 179

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
            + V D G YT KA N  G    +A +TV E     A PP F++R + +T       K + 
Sbjct: 180  QVV-DCGEYTCKASNEYGSVSCTATLTVTE-----AYPPTFLSRPKALTTFVGKAAKFLC 233

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             V+  PV  I W ++   +SPS             L ++N+  + D G Y C ASN  G 
Sbjct: 234  TVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQ-DRGIYSCKASNKFGA 292

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMD 971
                A +TI ++K  F+K L+ + ++   K + LECQ      V+  W  + +++ +G D
Sbjct: 293  DICQAELTI-IDKPHFIKELE-AVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKD 350

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQ-DF 1026
            ++ I  E +            D G   C   ++     +S  + V+E  P F++K+   +
Sbjct: 351  YK-IYFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREP-PSFVKKVDPSY 408

Query: 1027 EVKEKDVAILEVEIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
             +   + A L  ++  S    V W ++  E+ +    +  F     I  L I +  V D 
Sbjct: 409  LMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAI--LDITDVKVDDS 466

Query: 1085 GEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
            G YSC   ++    SC+ EV + E PP  I  L+   + +G  A  + E+   G   V W
Sbjct: 467  GTYSCEATNDVGSDSCSTEVVIKE-PPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNW 525

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195
            FKD  +I+ S   +L        L+I   +  D G+Y C    EVG   C A   ++EP 
Sbjct: 526  FKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCVATHLLKEPP 585

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
              F  ++ +F  +   T          E + V W K + VI++  K  +        L I
Sbjct: 586  -TFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTI 644

Query: 1256 RKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
                     +YTC+   +A S T +   +V+ P KI++     ++  G   TL       
Sbjct: 645  PDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGT 704

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P+   +W  + + +   K  + S  +  A L     E  D+G Y   + N  G +  E  
Sbjct: 705  PELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 764

Query: 1375 VTILDKPSPP--GKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVK 1431
             T+LD+   P   KP +  +DS     C  + +  G+  + + +  + +E+  ++   + 
Sbjct: 765  FTVLDRDIAPLFTKP-LRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIA 823

Query: 1432 NITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
             +  T +  I  +  N +  F   A N V   D+S       +++E       V KP   
Sbjct: 824  FVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGAL----IVQEPP---SFVTKPGSR 876

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXX 1546
                P   + L   F G     + W++  K+L +  + Y  +                  
Sbjct: 877  DVL-PGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSG 935

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
             Y C   N  G VE S  + +++ P   I   +  Q  K GD   +   + G PP ++ W
Sbjct: 936  TYTCKVSNVAGSVECSADLFVKE-PATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITW 994

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            + N  +L    ++ ++  E T+V+R+ ++    S +Y  EA N AG+      + V + P
Sbjct: 995  FANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKESP 1054



 Score =  240 bits (587), Expect = 3e-61
 Identities = 242/1077 (22%), Positives = 438/1077 (40%), Gaps = 75/1077 (6%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F KK  +++ V +      EC++   PE  + W     EI       ++ E  +   
Sbjct: 3965 PPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSV--- 4021

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             ++L++ ++     G YT  A N  G AS    LK+K    EPP   +    +   +G  
Sbjct: 4022 -AILEMHSLSVEDSGDYTCEARNAAGSASSSTSLKVK----EPPVFRKKPFPVETLKGAD 4076

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V L  ++ G P   ++W K+ + +   K     S+    SI IL      D G Y  KA 
Sbjct: 4077 VHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTA-DIGEYQCKAT 4135

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G       +T++ P       P F+ +  +I+      ++L   +      S+ W++
Sbjct: 4136 NDVGSDTCVGSVTMKAP-------PQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFK 4188

Query: 869  NN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            +  EI+  S+ I  ++  ENI  +  +     ++G Y C   N AG     A +++ +E 
Sbjct: 4189 DKGEIVRESDNIWISYS-ENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSV-LEP 4246

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
               V+   +S +   G T  LEC  S T  +STKW+ + KE++  +  +I    +     
Sbjct: 4247 AAIVEK-PESIKVTTGDTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLK 4305

Query: 986  XXXXXXXDVGVIKCIVKD----QETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVE 1039
                   D GV    V++          + V + I  P F RKL++         ++E +
Sbjct: 4306 IINVVPGDSGVYSFEVQNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECK 4365

Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094
            +  S    V+W  DG  I   + KY      +   L +      D G+Y+CI  +    +
Sbjct: 4366 VYGSPPISVLWFHDGNEISSGR-KYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSD 4424

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHI 1152
             C+A +TV E PP  + +     V  G+  TF   + KG     V WFK  +E+      
Sbjct: 4425 ECSAPLTVRE-PPSFVQKPDPMDVLTGSNVTFT-SIVKGSPPFTVSWFKGSTELVPGARC 4482

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             +++     +L+++D D   +GEY+C    E G + CT  L V+ P+I F  RL ++ + 
Sbjct: 4483 NVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRASCTTRLFVKAPAI-FVKRLNDYSIE 4541

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
                            + VTW K    +  +++  + +  K   L I   T +D  +Y C
Sbjct: 4542 KGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNC 4601

Query: 1269 VLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
             + +A  K +   ++ ++E PP  V      ++  G   +L       P+    W     
Sbjct: 4602 YIENASGKDSCSAQILILE-PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDT 4660

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             ++     K    +  A+L   +V+++D+G Y  R EN+ G       +T+ ++  PP  
Sbjct: 4661 KLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSF 4720

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKNITKTQTS-IQ 1441
               L           D  E  G   +    V   E  +  W      +K+    QTS + 
Sbjct: 4721 SRQLR----------DVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLD 4770

Query: 1442 NLKTNSSYRFRAYAVNEVDISDAS---ETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            N+ T + ++       +   +  +     +   K+I       P  + PL  +     E 
Sbjct: 4771 NIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGES 4830

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFN 1554
             +L C   G    KVTW +D +++++    + +Y EN                Y C A N
Sbjct: 4831 ADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVN 4890

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            + G+   +  + I+++ +     + + +  +   G+ + +   + G  P  V WYKN  +
Sbjct: 4891 EVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVE 4950

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            +       I  K    ++++K    + +  YT +A+N AG++    ++ V  +P KP
Sbjct: 4951 IHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSI-VIKEPKKP 5006



 Score =  238 bits (583), Expect = 1e-60
 Identities = 250/1090 (22%), Positives = 447/1090 (41%), Gaps = 69/1090 (6%)

Query: 633  PPTFSKKPKAQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F KK  A  V  +G  I LEC++   PE  + W     E+      +++  + +   
Sbjct: 3024 PPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSV--- 3080

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             ++L I        G Y   A N  G+AS    LK+K     PP   +    +   +G  
Sbjct: 3081 -ALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKA----PPVFTQKPPPVGALKGSD 3135

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKA 807
            VIL  ++ G P   + W K+ K V++      T  + DT S+ I    +  D G Y  KA
Sbjct: 3136 VILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDT-SLHIFN-LEAPDIGEYHCKA 3193

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G ++T A       T +  EPP F+ +  + +      ++L A V      S+ W 
Sbjct: 3194 TNEVG-SDTCAC------TVKFKEPPRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWL 3246

Query: 868  RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            ++  E+I  SE +  +F  +NI  +         SG Y C   N AG     A +T+ +E
Sbjct: 3247 KDKGEVIRESENVRISFV-DNIATLQLGSPEASQSGKYVCQIKNDAGMRECSAVLTV-LE 3304

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              T V+  +    T  G    LEC  + T  +S KW+ + +E+S      I         
Sbjct: 3305 PATIVEKPEPMTVTT-GNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVRNLASL 3363

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEV 1038
                    D G+    V+++   +   V   +      P F+R+L+D         +LE 
Sbjct: 3364 KIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLEC 3423

Query: 1039 EIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL----- 1091
             ++ S    V W  DG EII   K +  F    ++  L + +    D G Y+C+      
Sbjct: 3424 RVSGSAPISVGWFLDGNEIISSPKCQSSFAD--NVCTLTLSSLEPSDTGAYTCVAANVAG 3481

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
            +DES +A +TV E PP       + +V  G   TF   +       V+WFK   E+    
Sbjct: 3482 QDES-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGE 3539

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI 1206
               ++++    +L++ + +   +G+YSC    + G++ CT  L V+EP+  F  RL +  
Sbjct: 3540 ACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKEPA-TFVKRLADTS 3598

Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            +   +             + V+W K +  +  +    + +  K   L I + T +D  +Y
Sbjct: 3599 VETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQY 3658

Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
             C++ +   +   +  V V+E PP  ++         G  +TL       P+    W   
Sbjct: 3659 ACLIENEAGQDICEALVSVLE-PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKE 3717

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
               ++     K    +  ASL I KV+++D G Y  + EN+ G       + I ++  PP
Sbjct: 3718 HTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPP 3777

Query: 1385 GKPNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
                 L+    ++   + ++   N      + +  + + +     + +  +    T +Q 
Sbjct: 3778 SFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVAT-LQI 3836

Query: 1443 LKTNSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            L+T+ S+  ++   A N +  + +S       ++ E ++      KP+ ++     E   
Sbjct: 3837 LQTDQSHVGQYNCSASNPLGTASSSAKL----ILSEHEVPPFFDLKPV-SVDLALGESGS 3891

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
              C   G    K+TW +D ++++     K T  EN                Y C A N  
Sbjct: 3892 FKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVA 3951

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G+   S  +G+Q+ P   I   D  +  K  +       I G P  +V+WYK+  +++  
Sbjct: 3952 GKDSCSAQLGVQEPPRF-IKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQES 4010

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
             ++ ++ ++  +++ +  L    S  YT EA N AG++S   +LKV + P   + P  + 
Sbjct: 4011 SKFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVE 4070

Query: 1677 EISRESVTIE 1686
             +    V +E
Sbjct: 4071 TLKGADVHLE 4080



 Score =  238 bits (582), Expect = 1e-60
 Identities = 245/1087 (22%), Positives = 441/1087 (40%), Gaps = 68/1087 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            I P F+K  +      G    L+C++       ++W   G+E+   +   +A        
Sbjct: 772  IAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVEGT--- 828

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L+I+ V     G +T  A N  G       L ++    EPP  +    S  V  G +
Sbjct: 829  -ASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQ----EPPSFVTKPGSRDVLPGSA 883

Query: 752  VILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            V L +   G+   TI W K +K +        TK   +  S   L   K  D G YT K 
Sbjct: 884  VCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSE--SSLELYAVKTSDSGTYTCKV 941

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITW 866
             N  G  E SA + V+EP         FI + +   + +KG   +L  +VT  P   ITW
Sbjct: 942  SNVAGSVECSADLFVKEPAT-------FIEKLEPSQLLKKGDGTQLACKVTGTPPIKITW 994

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            + N+  +  S     +F      L +T+V  E DSG+Y C A N AG S H   + I  E
Sbjct: 995  FANDRELRESSKHKMSFAESTAVLRLTDVAIE-DSGEYMCEAQNEAG-SDHCTGIVIVKE 1052

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRXXX 983
               F K   KS E  +   V+L  + + T      W+ +   + SG  ++  +Q+ +   
Sbjct: 1053 SPYFTKEF-KSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQD-QLVS 1110

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEI 1040
                     D G  +C V ++  S+    + T+   P FI+K++         A  +  +
Sbjct: 1111 LQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIEATSSLRGGTAAFQATL 1170

Query: 1041 N-SETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--- 1095
              S    V W +D + I    N +  FE   ++  LY+    V  +G+Y C  ++++   
Sbjct: 1171 KGSLPITVTWLKDNDEITEDDNIRMTFEN--NVASLYLSGIEVKHDGKYVCQAKNDAGIQ 1228

Query: 1096 -CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153
             C+A ++V E P  I+    +  V +G+ AT +++ +    +  +WFKDG E+      +
Sbjct: 1229 RCSALLSVKE-PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYK 1287

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFIL 1207
            +++      LKI   +  D+GEY+ EV    G S C A + V +  I  +FT +L +   
Sbjct: 1288 ISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDS 1347

Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
            +  +      +      + + W+K    I  ++K           L I +    D   YT
Sbjct: 1348 IKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYT 1407

Query: 1268 CVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            C   +    ++    + V+ PP  V+  +   +  G+ V L            +W  ++K
Sbjct: 1408 CSATNKAGHSQCSGHLTVKEPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNK 1467

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             +          D  S  L +   +  D+G Y  +L N+ G    +  + + + P    K
Sbjct: 1468 ELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQFIKK 1527

Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLK 1444
            P+ + +  +  +  + E + TG   I + + ++  EI       +  +    T  I N +
Sbjct: 1528 PSPVLVLRNGQSTTF-ECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNAR 1586

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTC 1503
              +S  +   A N+   +  S          E K++ P +  + L+ +    + D+EL C
Sbjct: 1587 VENSGTYVCEARNDAGTASCSI---------ELKVKEPPIFIRELEPVEVVKDSDVELEC 1637

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXX---XXXXXYKCIAFNDHGEV 1559
               G    +VTW ++ K++++ K  T   +                  Y+CI  N+ G  
Sbjct: 1638 EVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSC 1697

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
              S  V +++ P      E++    K    +  T  + G PP  + W K+   LE +   
Sbjct: 1698 ACSARVALKEPPSFIKKIENVTTVLKSSATFQST--VAGSPPISITWLKDDQILEENDNV 1755

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            +I+ ++  + ++++ +   HS +YT +A N +G       L V +     E    +    
Sbjct: 1756 HISFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPAQIIEKAKSVDVTE 1815

Query: 1680 RESVTIE 1686
            ++ VT+E
Sbjct: 1816 KDPVTLE 1822



 Score =  231 bits (564), Expect = 2e-58
 Identities = 240/1063 (22%), Positives = 431/1063 (40%), Gaps = 59/1063 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PPTF KK        G  + L+  +       + W+ KG+E++ ++     I+       
Sbjct: 584  PPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWM-KGQEVIKEDG---KIKMSFSNGV 639

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +VL I +V+    G YT +A N  G  +    L +K    EP ++IE  + + V  G+  
Sbjct: 640  AVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVK----EPAKIIERAELIQVTAGDPA 695

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810
             L   V G P     W K+ +P+ A         ++I  LK    ++ D G YT +  N 
Sbjct: 696  TLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNE 755

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G +      TV +        PLF    + +     G  +L  ++  +    ++W+++ 
Sbjct: 756  VGSSSCETTFTVLD----RDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDG 811

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVT 929
            + ++ S+     F      L I+ VD   D+G++ C A+NS G K S GA +    E  +
Sbjct: 812  KELTASDRYQIAFVEGTASLEISRVDMN-DAGNFTCRATNSVGSKDSSGALIV--QEPPS 868

Query: 930  FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            FV     S +   G  V L+   Q S  ++ KW+   KE+       I +E         
Sbjct: 869  FVTK-PGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELY 927

Query: 988  XXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEK-DVAILEVEIN- 1041
                 D G   C V +     E S  L VKE    FI KL+  ++ +K D   L  ++  
Sbjct: 928  AVKTSDSGTYTCKVSNVAGSVECSADLFVKEPAT-FIEKLEPSQLLKKGDGTQLACKVTG 986

Query: 1042 SETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----C 1096
            +    + W   D E+ +  K+K  F +   + +L   + ++ D GEY C  ++E+    C
Sbjct: 987  TPPIKITWFANDRELRESSKHKMSFAESTAVLRL--TDVAIEDSGEYMCEAQNEAGSDHC 1044

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
            T  + +V+  P      ++ +V K        E+       + WFKD + ++     +  
Sbjct: 1045 TG-IVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTF 1103

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
            +  +   L++      DAGEY C    EVG+S C+A +T+ EP  +F  ++     +   
Sbjct: 1104 LQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPP-SFIKKIEATSSLRGG 1162

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
            T A+         + VTW K    I + +   +  +    +L +         +Y C   
Sbjct: 1163 TAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAK 1222

Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            +     +    + V+ P  I++      + +G   TL V +    + + +W  + + +  
Sbjct: 1223 NDAGIQRCSALLSVKEPATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTL 1282

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNI 1389
                K S+    + L I   E  D+G Y   ++N+ G +  + ++ +LD   PP     +
Sbjct: 1283 GPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKL 1342

Query: 1390 LEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNS 1447
             ++DS   +    E    G+  I I +  + QEI  ++         T    I  L+   
Sbjct: 1343 RKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTD 1402

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            S  +   A N+   S  S     +  +KE       VEKP ++    P   ++L  + GG
Sbjct: 1403 SGTYTCSATNKAGHSQCSG----HLTVKEPPY---FVEKP-QSQDVNPGTRVQLKALVGG 1454

Query: 1508 VPQPKVTWYRDGKKLK--TAKATYENRXXXXXX--XXXXXXXXXYKCIAFNDHGEVETSC 1563
                 + W++D K+L    A++ +++                  Y C   ND G   +  
Sbjct: 1455 TAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKA 1514

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             + +++ P        +      G        + G P   V WY +GN++ + ++Y I+ 
Sbjct: 1515 TIFVKEPPQFIKKPSPVLVLRN-GQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISF 1573

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             +  +  +I   +  +S  Y  EA N AGT+S  + LKV + P
Sbjct: 1574 VDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPP 1616



 Score =  230 bits (563), Expect = 3e-58
 Identities = 266/1189 (22%), Positives = 477/1189 (40%), Gaps = 96/1189 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F++K+    +  G T  F+  ++G     +TW +    I    + +M +++ NVA+L 
Sbjct: 1147 PSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFEN-NVASLY 1205

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            +  +  +  G + C AKN AG    +  L V+ P +     +++             D+ 
Sbjct: 1206 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIMEEAVSI-------------DVT 1252

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +G P T                 L+ +     E    W   G+E+       +++   + 
Sbjct: 1253 QGDPAT-----------------LQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTV- 1294

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               S+LKI + +K   G YT    N  G +S    + +      PP   + L+ M   +G
Sbjct: 1295 ---SILKIISTEKKDSGEYTFEVQNDVGRSSCKASINV-LDLIIPPSFTKKLRKMDSIKG 1350

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKA 807
              + L   V G+   +I W K+++ + A      S  D  +   +   +  D G YT  A
Sbjct: 1351 SFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSA 1410

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G ++ S  +TV+       EPP F+ + Q   V     ++L A V      +I W+
Sbjct: 1411 TNKAGHSQCSGHLTVK-------EPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWF 1463

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++N+ + P    +   D  +  L + +  +  DSG Y C  SN  G +S  A + +  E 
Sbjct: 1464 KDNKELHPGAARSVWKDDTSTILELFSAKA-ADSGTYICQLSNDVGTTSSKATIFVK-EP 1521

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
              F+K          G++   ECQ + T  +   WY +  EI+ +    I          
Sbjct: 1522 PQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQ 1581

Query: 986  XXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEI 1040
                   + G   C  ++       S  L VKE  P FIR+L+  E VK+ DV  LE E+
Sbjct: 1582 ISNARVENSGTYVCEARNDAGTASCSIELKVKEP-PIFIRELEPVEVVKDSDVE-LECEV 1639

Query: 1041 NSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095
               T  +V W ++ + I+  K KY   ++  +  L+I      D GEY CI+ +E    +
Sbjct: 1640 MGTTPFEVTWLKNNKEIRSGK-KYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCA 1698

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154
            C+A V + E PP  I +++N      + ATF+  +     + + W KD   ++ ++++ +
Sbjct: 1699 CSARVALKE-PPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHI 1757

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            + +     L++   D   +G Y+C    E G  +C A L V+EP+     +     +   
Sbjct: 1758 SFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPA-QIIEKAKSVDVTEK 1816

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-V 1269
            +      V      L V W K    I  +  F++  +    +  I+   + D  +YT  V
Sbjct: 1817 DPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 1876

Query: 1270 LLDAKSTT---KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
              D  S++    L+V   + PP       +     GS + +          + +W  + K
Sbjct: 1877 ENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGK 1936

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             I      +      + SL +  +E  D   Y  ++ N  G       +T+ + PS   K
Sbjct: 1937 EISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVK 1996

Query: 1387 PNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---TKTQTSIQN 1442
            P   + I  S++     +    G      + +++ + D  E +S        +  TS  N
Sbjct: 1997 PERQQAIPDSTVEF---KAVLKGTPP---FKIKWLK-DDVELVSGPKCFIGLEGSTSFLN 2049

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
            L +  S +   Y     +   +   T    V +  K     V+K   +   +  +   L 
Sbjct: 2050 LYSVDSSKTGQYTCQVTNDVGSDSCTTMLLVTEPPKF----VKKLEASKIIKAGDSARLE 2105

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            C   G P+ +V WYR+  +L TA   Y     ++                + C A N  G
Sbjct: 2106 CKITGSPEIQVVWYRNEHEL-TASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAG 2164

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
                S  V +++ PV + S   I +  K   E  +   + G PP EV+WYK+  +L + K
Sbjct: 2165 STSCSTKVIVKEPPVFS-SFPPIVETLK-NTEVSLECELSGTPPFEVVWYKDKRQLRSSK 2222

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +Y + +K   + I I  ++ +   +Y  +A N  G+ +    +K+ + P
Sbjct: 2223 KYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKEPP 2271



 Score =  229 bits (559), Expect = 8e-58
 Identities = 243/1085 (22%), Positives = 438/1085 (40%), Gaps = 78/1085 (7%)

Query: 626  ADILEGIPPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
            AD+    P TF +K + +Q + +G    L C++   P   I W     E+       ++ 
Sbjct: 952  ADLFVKEPATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHKMSF 1011

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
                    +VL++T+V     G Y   A N  G      ++ +K    E P   +  KS+
Sbjct: 1012 AEST----AVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVK----ESPYFTKEFKSI 1063

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEG 801
             V +   V+L A+V G P   ITW K+N  +++     T       S+ +LK     D G
Sbjct: 1064 EVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLK-FVAADAG 1122

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             Y  +  N  G +  SA +T+ EP       P FI + +  +    GT    A +  +  
Sbjct: 1123 EYQCRVTNEVGSSTCSARVTLREP-------PSFIKKIEATSSLRGGTAAFQATLKGSLP 1175

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             ++TW ++N+ I+  + I   F+     L ++ ++ + D G Y C A N AG     A +
Sbjct: 1176 ITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHD-GKYVCQAKNDAGIQRCSALL 1234

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDHR----- 973
            ++  E  T ++    S +  +G    L+ + S T  +S KW+ + +E++ G  ++     
Sbjct: 1235 SVK-EPATIMEEAV-SIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTD 1292

Query: 974  -----EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE- 1027
                 +II   +            DVG   C  K       L++    P F +KL+  + 
Sbjct: 1293 TVSILKIISTEKKDSGEYTFEVQNDVGRSSC--KASINVLDLIIP---PSFTKKLRKMDS 1347

Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
            +K   + +  +   S    + W +D + I    +K+ F    +   L I      D G Y
Sbjct: 1348 IKGSFIDLECIVAGSHPISIQWFKDDQEISAS-DKHKFSFHDNTAFLEISQLEGTDSGTY 1406

Query: 1088 SCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFK 1141
            +C   +++    C+  +TV E PP  + + Q+Q VN G +   +  L  G A   ++WFK
Sbjct: 1407 TCSATNKAGHSQCSGHLTVKE-PPYFVEKPQSQDVNPGTRVQLKA-LVGGTAPMTIKWFK 1464

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN 1197
            D  E+       +  D     L+++     D+G Y C+    VG +   A + V+EP   
Sbjct: 1465 DNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQF 1524

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
                 P  +L    +  +         + V+WY   + I D  K+ +       T  I  
Sbjct: 1525 IKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISN 1584

Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ 1316
               ++   Y C   +   T    +E+ V+ PP  +       + + SDV L  +      
Sbjct: 1585 ARVENSGTYVCEARNDAGTASCSIELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTP 1644

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
                W+ N+K I+  K    S       L I K + +D G Y+  + N  G       V 
Sbjct: 1645 FEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVA 1704

Query: 1377 ILDKPSPPGK-PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNIT 1434
            + + PS   K  N+  +  SS      +    G+  I I ++ + Q ++  + + +    
Sbjct: 1705 LKEPPSFIKKIENVTTVLKSSATF---QSTVAGSPPISITWLKDDQILEENDNVHISFED 1761

Query: 1435 KTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
               T  ++++    S R+   A NE  I    E    + +++E    +  +EK  K++  
Sbjct: 1762 SVATLQVRSVDNGHSGRYTCQAKNESGI----ERCYAFLLVQEP---AQIIEKA-KSVDV 1813

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXXXXXXXXX-YK 1549
               + + L C+  G P+ KV W +DGK++  ++    ++EN                 Y 
Sbjct: 1814 TEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYT 1873

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYK 1608
                ND G       + +  + +     + + +  KV G    +   + G  P    W+K
Sbjct: 1874 FKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFK 1933

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS- 1667
            +G ++    +Y +   E T  + +  L+   ++ YT + SN AG ++    L V + PS 
Sbjct: 1934 DGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSF 1993

Query: 1668 --KPE 1670
              KPE
Sbjct: 1994 LVKPE 1998



 Score =  227 bits (554), Expect = 3e-57
 Identities = 245/1135 (21%), Positives = 455/1135 (40%), Gaps = 68/1135 (5%)

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXX 625
            +L +R  + +D    T   +    F   T  L I    ++D G+  T             
Sbjct: 800  SLPMRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGN-FTCRATNSVGSKDSS 858

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAI 684
              ++   PP+F  KP ++ V  GS + L+          I W FKG+ E+V   +  +  
Sbjct: 859  GALIVQEPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKW-FKGDKELVSGGSCYITK 917

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-S 743
            E+      S L++  VK    GTYT    N  G       L +    KEP   IE L+ S
Sbjct: 918  ETSE----SSLELYAVKTSDSGTYTCKVSNVAGSVECSADLFV----KEPATFIEKLEPS 969

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEG 801
             ++++G+   L+ +V G P   ITW  N++ ++  +    S  ++ ++  L    ++D G
Sbjct: 970  QLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSG 1029

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             Y  +A+N  G    + ++ V+       E P F   F+ I V ++  + L+A V   P 
Sbjct: 1030 EYMCEAQNEAGSDHCTGIVIVK-------ESPYFTKEFKSIEVLKEYDVMLLAEVAGTPP 1082

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
              ITW+++N  +            + + L +    +  D+G+Y+C  +N  G S+  ARV
Sbjct: 1083 FEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVA-ADAGEYQCRVTNEVGSSTCSARV 1141

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGR 980
            T+  E  +F+K ++ +     G        + S  ++  W  +  EI+  D+  +  E  
Sbjct: 1142 TLR-EPPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENN 1200

Query: 981  XXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAIL 1036
                          G   C  K+    Q  S +L VKE     + +    +V + D A L
Sbjct: 1201 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP-ATIMEEAVSIDVTQGDPATL 1259

Query: 1037 EVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094
            +V+ + ++     W +DG+ +     KY       +  L I +T   D GEY+  ++++ 
Sbjct: 1260 QVKFSGTKEISAKWFKDGQEL-TLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDV 1318

Query: 1095 ---SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQF 1148
               SC A + V++L  PP    +L+     KG+    E  +     + ++WFKD  EI  
Sbjct: 1319 GRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISA 1378

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204
            S+  + +       L+I   +  D+G Y+C    + G+S+C+  LTV+EP   + +  P+
Sbjct: 1379 SDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPP--YFVEKPQ 1436

Query: 1205 FILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
               V   T   L   +     + + W+K    +      ++  D     L +      D 
Sbjct: 1437 SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADS 1496

Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEW 1321
              Y C L +   TT  K  + V+ PP+ +       + R G   T        P+    W
Sbjct: 1497 GTYICQLSNDVGTTSSKATIFVKEPPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSW 1556

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
             ++   I   +    S     A+  I      ++G Y     N+ G A   + + + + P
Sbjct: 1557 YLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPP 1616

Query: 1382 SPPGKPNILE-IDSSSINICWDEPENTGNSTI-IYYVVEYQEIDT-TEWISVKNITKTQT 1438
                +   +E +  S + +   E E  G +   + ++   +EI +  ++   + ++    
Sbjct: 1617 IFIRELEPVEVVKDSDVEL---ECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYL 1673

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             I     +    ++    NE      S        +KE     P+  K ++N+TT     
Sbjct: 1674 HITKCDPSDVGEYQCIIANEGGSCACSARV----ALKE----PPSFIKKIENVTTVLKSS 1725

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENR-XXXXXXXXXXXXXXXYKCIAFN 1554
                    G P   +TW +D + L+       ++E+                 Y C A N
Sbjct: 1726 ATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKN 1785

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            + G       + +Q+   I    + +    K  D   +  V+ G P  +V W K+G ++ 
Sbjct: 1786 ESGIERCYAFLLVQEPAQIIEKAKSVDVTEK--DPVTLECVVAGTPELKVKWLKDGKQIV 1843

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              + ++++ +   +  RI+ + +  S +YT +  N  G+SS +  L+V D+   P
Sbjct: 1844 PSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPP 1898



 Score =  221 bits (541), Expect = 1e-55
 Identities = 250/1121 (22%), Positives = 443/1121 (39%), Gaps = 63/1121 (5%)

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
            F  S   L V +  + H    T             A +L   P    +K K+  V E   
Sbjct: 1759 FEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPAQIIEKAKSVDVTEKDP 1818

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            + LEC +   PE  + WL  G++IVP    S++ E+++  +    +I +V K   G YT 
Sbjct: 1819 VTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF----RIQSVMKQDSGQYTF 1874

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
               N  G +S    L++   +  PP   + L  M    G S+ +  +V G+   +  W K
Sbjct: 1875 KVENDFGSSSCDAYLRV-LDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFK 1933

Query: 771  NNKPVKALPTKSDGDTHSITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            + K + +   K     H  T+   +   +++D   YT K  N  G    S ++TV+    
Sbjct: 1934 DGKEI-STSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVK---- 1988

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886
               EPP F+ + +        T++  A +   P   I W +++ E++S  +      +G 
Sbjct: 1989 ---EPPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFI-GLEGS 2044

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
               L + +VDS   +G Y C  +N  G  S    + +  E   FVK L+ S   + G + 
Sbjct: 2045 TSFLNLYSVDSS-KTGQYTCQVTNDVGSDSCTTMLLV-TEPPKFVKKLEASKIIKAGDSA 2102

Query: 947  ILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003
             LEC+   S  +   WY N+ E++  D  ++                 D G   C  ++ 
Sbjct: 2103 RLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNP 2162

Query: 1004 ---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPK 1059
                  ST ++VKE  P F       E  +     LE E++ +   +VVW +D   ++  
Sbjct: 2163 AGSTSCSTKVIVKEP-PVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSS 2221

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQN 1115
            K KY    +     ++I N    D GEY C  ++E    +C   V + E PP+ I++L +
Sbjct: 2222 K-KYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKE-PPKFISKLNS 2279

Query: 1116 QKVNKGNKATFEIELTKGDAL-VRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
              V  G  A  +  +     + V+W K+  E I+ S +I+++       L+    +  +A
Sbjct: 2280 LTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANA 2339

Query: 1174 GEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            G+Y C+V N     +  A LTV EP++    +     +    T A          L V W
Sbjct: 2340 GKYICQVKNDGGVRENMATLTVLEPAV-IIEKAGSMTVTVGETCALECKVAGTPELSVEW 2398

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE-- 1285
            YK   ++  ++K       K  +L I    ++D   YT  + +   KS+    V+V +  
Sbjct: 2399 YKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRM 2458

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSAS 1344
             PP      ++     G+   L          +  W    +KI+   K+ + +      +
Sbjct: 2459 VPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKY-QTTFSDNVCT 2517

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            L +  ++++D G Y     N  G  +    +T+ + PS   +P  LE+     NI +   
Sbjct: 2518 LQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEPLEVLPGK-NITFTSV 2576

Query: 1405 -ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
               T    + ++    + +           T  +  + N+  + S  +     N  +   
Sbjct: 2577 IRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSN--NAGQ 2634

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            AS TT  +  +KE      T  K L + + EP + I L   + G     VTW +DG  + 
Sbjct: 2635 ASCTTRLF--VKE----PATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSIT 2688

Query: 1524 TAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
             ++     T E                 Y C   N+ G      +V   + P      E 
Sbjct: 2689 PSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRDACDALVSTLEPPYFVTELEP 2748

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            ++    VGD   +   + G P   V W+K   KL +  EY        + +   ++  + 
Sbjct: 2749 LEA--SVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSIND 2806

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            S +YT  A N+ GT++ +   ++ ++   P     +++I +
Sbjct: 2807 SGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQ 2847



 Score =  221 bits (539), Expect = 2e-55
 Identities = 286/1305 (21%), Positives = 502/1305 (38%), Gaps = 82/1305 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F +  +      G  I L+C++   PE  I+W  +  ++       +  ++++    
Sbjct: 3680 PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNV---- 3735

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L I  V     G YT  A N  G  +   VL IK   K PP     LK +    G  V
Sbjct: 3736 ASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKE-RKLPPSFARKLKDVHETLGFPV 3794

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLKAENS 810
                ++ G+    ++W K+ + +K          H +  L+  +      G Y   A N 
Sbjct: 3795 AFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNP 3854

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYR 868
             G A +SA + + E    +  PP F  +    ++ + E G+ K    VT      ITW +
Sbjct: 3855 LGTASSSAKLILSE----HEVPPFFDLKPVSVDLALGESGSFK--CHVTGTAPIKITWAK 3908

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            +N  I P              L +  V ++ D+G Y C ASN AGK S  A++ +  E  
Sbjct: 3909 DNREIRPGGNYKMTLVENTATLTVLKV-AKGDAGQYTCYASNVAGKDSCSAQLGVQ-EPP 3966

Query: 929  TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             F+K L +S   ++ +    EC+   S  +   WY ++ EI       +  E        
Sbjct: 3967 RFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEM 4026

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                  D G   C  ++      +ST L VKE  P F +K    E  +     LE E+  
Sbjct: 4027 HSLSVEDSGDYTCEARNAAGSASSSTSLKVKEP-PVFRKKPFPVETLKGADVHLECELQG 4085

Query: 1043 ETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097
                 V W +D   ++  K KY       +  ++I N    D GEY C   ++    +C 
Sbjct: 4086 TPPFQVSWHKDKRELRSGK-KYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCV 4144

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEI-QFSNHIQLT 1155
              VT+ + PP+ + +L +     G +   +  +   + + V WFKD  EI + S++I ++
Sbjct: 4145 GSVTM-KAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWIS 4203

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPAN 1211
                   L+    +  +AG+Y+C++ N     +C A L+V EP+    +  PE I V   
Sbjct: 4204 YSENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEPAA--IVEKPESIKVTTG 4261

Query: 1212 TDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                L   +     L   W+K    +    K+ +    K   L I      D   Y+  +
Sbjct: 4262 DTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEV 4321

Query: 1271 LD--AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
             +   K + K+ ++V +   PP      +E     GS V +       P  +  W  +  
Sbjct: 4322 QNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGN 4381

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             I   +  + ++   + +LT+  +E  DAG Y     N  G  +    +T+ + PS   K
Sbjct: 4382 EISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQK 4441

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
            P+ +++ + S        + +   T+ ++    + +           +  +  + ++ T+
Sbjct: 4442 PDPMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTS 4501

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIF 1505
             S  +     NE     AS TT  +       +++P +  K L + + E  + + L   F
Sbjct: 4502 QSGEYTCIVSNEA--GRASCTTRLF-------VKAPAIFVKRLNDYSIEKGKPLILEGTF 4552

Query: 1506 GGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
             G P   VTW ++G  +  ++     T E                 Y C   N  G+   
Sbjct: 4553 SGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSC 4612

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            S  + I + P      E +K    VGD   +   + G P   V WYK   KL       +
Sbjct: 4613 SAQILILEPPYFVKQLEPVKVT--VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKM 4670

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
              K   + +   ++  S S +Y   A N+ G  S    L V ++   P     +R++ +E
Sbjct: 4671 HFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV-QE 4729

Query: 1682 SVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            +V +         G E   ++ Y   K   D+   I+ + +D ++ T  I K + +    
Sbjct: 4730 TVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPN-IQTSFLD-NIATLNIFKTDRSLSGQ 4787

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            +   A NP+G   A     +++    + P           +  ES  +        G  P
Sbjct: 4788 YSCTATNPIG--SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADL---ECHVTGTQP 4842

Query: 1799 I-IDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            I + +  + ++   G  ++           I K+    + Q+  YA NE+G     +   
Sbjct: 4843 IKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKD---SCTA 4899

Query: 1856 KITIGKTLTPPSQPRNF--VVSESTSRSVTLKWTEPESNGGSPIT 1898
            ++ I + L PPS  +     V E+   S  L   E    G  PIT
Sbjct: 4900 QLNIKERLIPPSFTKKLSETVEETEGNSFKL---EGRVAGSQPIT 4941



 Score =  215 bits (526), Expect = 8e-54
 Identities = 237/1074 (22%), Positives = 416/1074 (38%), Gaps = 65/1074 (6%)

Query: 633  PPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F KK +A + +  G    LEC++   PE  + W     E+   +   +     +   
Sbjct: 2083 PPKFVKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSV--- 2139

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             +V+++ ++     G +   A N  G  S    +++K        P ++E LK+      
Sbjct: 2140 -AVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNT----- 2193

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
              V L  ++ G P   + W K+ + +   K     S     SI IL  +   D G Y  K
Sbjct: 2194 -EVSLECELSGTPPFEVVWYKDKRQLRSSKKYKVASKNFHASIHILNVEST-DIGEYHCK 2251

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A+N  G       + ++EP       P FI++   +TV      +L A +      S+ W
Sbjct: 2252 AQNEVGSDACVCAVKLKEP-------PKFISKLNSLTVVAGEPAELQASIEGAQPISVQW 2304

Query: 867  YRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
             +  E +I  SE I  +F      L    V+   ++G Y C   N  G   + A +T+ +
Sbjct: 2305 LKEKEEVIRESENIRISFVNNVATLQFAKVEPA-NAGKYICQVKNDGGVRENMATLTV-L 2362

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983
            E    ++    S     G+T  LEC+ + T  +S +WY + K ++     +     +   
Sbjct: 2363 EPAVIIEKAG-SMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISS 2421

Query: 984  XXXXXXXXXDVGVIKCIVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAILE 1037
                     D G     V++   ++S   VV    +   P F R+L+D         ILE
Sbjct: 2422 LKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILE 2481

Query: 1038 VEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
             ++  S    + W  +   I     KY      ++  L + +    D G Y+C+  +   
Sbjct: 2482 CKVAGSSPISIAWFHEKTKIVSGA-KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAG 2540

Query: 1094 -ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151
             + C A +TV E PP  +   +  +V  G   TF   +       V WF+   E+   N 
Sbjct: 2541 SDECRALLTVQE-PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNR 2599

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFIL 1207
              +  +    +L++++ D+  +GEY+C V N+     CT  L V+EP+  F  +L +  +
Sbjct: 2600 CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA-TFVKKLSDHSV 2658

Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
             P  +            + VTW K    I  +E+  +++  K   L I   T+ D   Y+
Sbjct: 2659 EPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYS 2718

Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            C + +   +      V  +E PP  V          G  V+L       P+    W    
Sbjct: 2719 CEIENEAGRDACDALVSTLE-PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGD 2777

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
              ++     +    +  A+L   KV   D+G Y    EN+ G A  +    I ++  PP 
Sbjct: 2778 TKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPS 2837

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE---IDTTEWISVKNITKTQTSIQN 1442
                L+    ++ +          S  I  V  Y++   +   E + +  +    T ++ 
Sbjct: 2838 FARQLKDIEQTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDDENLQMSFVDNVAT-LKI 2895

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
            L+T+ S+  +        +  AS T       +E K +SP  +    +I     E  +  
Sbjct: 2896 LQTDLSHSGQYSCSASNPLGTASSTARL--TAREPK-KSPFFDIKPVSIDVIAGESADFE 2952

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            C   G    +VTW +D K+++           N                Y C A ND G+
Sbjct: 2953 CHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 3012

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
               S  + +++ P   I   D  +  K G+   +   I G P  +V+W++N ++L    +
Sbjct: 3013 DMCSAQLSVKEPPKF-IKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWK 3071

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            YN++     +++ I E     +  Y  EA N  G +S    LKV   P   + P
Sbjct: 3072 YNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKP 3125



 Score =  209 bits (511), Expect = 6e-52
 Identities = 235/1069 (21%), Positives = 419/1069 (39%), Gaps = 60/1069 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F KKP      +G+D+ LEC L   P   ++W     E+   +   +  E+ +    
Sbjct: 4059 PPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLL---- 4114

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + + I NV     G Y   A N  G  +    + +K     PPQ ++ L  +    G+ V
Sbjct: 4115 TSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKA----PPQFVKKLTDISTIIGKEV 4170

Query: 753  ILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809
             L   + G    ++ W K+  + V+         + +I  L+  + +  + G YT + +N
Sbjct: 4171 QLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPANAGKYTCQIKN 4230

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G+ E  A ++V        EP   + + + I V    T  L   V+  P  S  W+++
Sbjct: 4231 DAGMQECYATLSV-------LEPAAIVEKPESIKVTTGDTCTLECTVSGTPELSTKWFKD 4283

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKV 928
             + ++       +F  +   L I NV    DSG Y     N  GK S   +V+I V +++
Sbjct: 4284 GKELTSDNKYKISFFNKVSGLKIINVVPG-DSGVYSFEVQNPVGKDS--CKVSIQVSDRI 4340

Query: 929  TFVKHLQKSYETE--EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
                  +K  ET    G +V++EC+   S  +S  W+H+  EIS     +          
Sbjct: 4341 IPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCAL 4400

Query: 985  XXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVE 1039
                    D G   CI  +     E S  L V+E  P F++K    +V    +V    + 
Sbjct: 4401 TVNMLEEADAGDYTCIATNVAGSDECSAPLTVREP-PSFVQKPDPMDVLTGSNVTFTSIV 4459

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
              S    V W +    + P   + +   +  + +L + +      GEY+CI+ +E+  A 
Sbjct: 4460 KGSPPFTVSWFKGSTELVPGA-RCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRAS 4518

Query: 1100 VTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
             T    V+ P   + RL +  + KG     E   +    + V W K+G  +  S    +T
Sbjct: 4519 CTTRLFVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNIT 4578

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
               K   L+I    ++D+G+Y+C +    G   C+A + + EP   F  +L E + V   
Sbjct: 4579 TTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILEPPY-FVKQL-EPVKVTVG 4636

Query: 1212 TDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-- 1268
              A L  ++     + V+WYK  + +  T    +       TL+  +    D  EY C  
Sbjct: 4637 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRA 4696

Query: 1269 --VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
               + +  S+T L V+  + PP      R+ +   G  V            +  W  + K
Sbjct: 4697 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGK 4756

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             +K   + + S     A+L I K + + +G Y     N  G A     + + +  +PP  
Sbjct: 4757 PLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFF 4816

Query: 1387 PNILEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNL 1443
               L    + +    D E   TG   I + +  + +EI +     +  +  +   +I  +
Sbjct: 4817 DIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKV 4876

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
                S ++  YAVNEV     +        IKE  I     +K  + +        +L  
Sbjct: 4877 DKGDSGQYTCYAVNEVGKDSCTAQLN----IKERLIPPSFTKKLSETVEETEGNSFKLEG 4932

Query: 1504 IFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEV 1559
               G     V WY++  ++      +  ++N                 Y C A ND G  
Sbjct: 4933 RVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSA 4992

Query: 1560 E-TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
              TS +V  + K                GD   ++  ++G  P  + W K G +++    
Sbjct: 4993 LCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPSDR 5052

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             + +    T+++ +KE  ++ S  Y  +ASN AG+ + +  + + +KP+
Sbjct: 5053 CSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPA 5101



 Score =  199 bits (485), Expect = 8e-49
 Identities = 196/784 (25%), Positives = 321/784 (40%), Gaps = 56/784 (7%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            IPP+F++K K      GS +++EC++   P   + W   G EI         +  +    
Sbjct: 4341 IPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNT--- 4397

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
            C+ L +  +++   G YT +A N  G  E S P+ +      +EPP  ++    M V  G
Sbjct: 4398 CA-LTVNMLEEADAGDYTCIATNVAGSDECSAPLTV------REPPSFVQKPDPMDVLTG 4450

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             +V  ++ V G+P  T++W K +  +   A    S  D+     L        G YT   
Sbjct: 4451 SNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTSQSGEYTCIV 4510

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G A  +  + V+ P        +F+ R  + ++++   + L    +  P  S+TW 
Sbjct: 4511 SNEAGRASCTTRLFVKAPA-------IFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWK 4563

Query: 868  RN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            +N  N I S    IT       +E++ + V+   DSG Y C   N++GK S  A++ I +
Sbjct: 4564 KNGINVIASQRCNITTTEKSAILEILSSTVE---DSGQYNCYIENASGKDSCSAQILI-L 4619

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983
            E   FVK L+   +   G +  L+CQ + T  +   WY    ++      ++  +     
Sbjct: 4620 EPPYFVKQLE-PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVAT 4678

Query: 984  XXXXXXXXXDVGVIKC----IVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILE 1037
                     D G   C     V +  +ST L V+E    P F R+L+D +       + E
Sbjct: 4679 LVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 4738

Query: 1038 VEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LR 1092
              ++ SE   V W +DG+ +K   N        +I  L I  T     G+YSC     + 
Sbjct: 4739 CAVSGSEPISVSWYKDGKPLKDSPN-IQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIG 4797

Query: 1093 DESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149
              S  A++ + E   PP     L       G  A  E  +T    + V W KD  EI+  
Sbjct: 4798 SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSG 4857

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLP 1203
             + Q++       L I   D  D+G+Y+C    EVG   CTA L ++E  I  +FT +L 
Sbjct: 4858 GNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 4917

Query: 1204 EFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
            E +         L   +   + + V WYK    I  T    ++       L +++ +  D
Sbjct: 4918 ETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMAD 4977

Query: 1263 QCEYTC-VLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
               YTC    DA S   T+ + ++  + PP    +        G  V L    Q      
Sbjct: 4978 AGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIR 5037

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
             +W+   + +K       S  S +A L +K+    D+G Y  +  N  G    +  VTI 
Sbjct: 5038 IQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIK 5097

Query: 1379 DKPS 1382
            +KP+
Sbjct: 5098 EKPA 5101



 Score =  195 bits (476), Expect = 1e-47
 Identities = 218/1100 (19%), Positives = 413/1100 (37%), Gaps = 60/1100 (5%)

Query: 602  APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAI 660
            A L D G+  T             A +    PP+F KK    Y+   G    L C+L   
Sbjct: 367  AKLKDSGT-YTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGS 425

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P   + W    +E+     + ++  +      ++L IT+VK    GTY+  A N  G  S
Sbjct: 426  PVIQVTWFKNNKELSESNTVRMSFVNSE----AILDITDVKVDDSGTYSCEATNDVGSDS 481

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780
                + I    KEPP  I+ L+   + +G + +L  ++ G     + W K+ K +++   
Sbjct: 482  CSTEVVI----KEPPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKK 537

Query: 781  KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ 840
                   +   L+        V   +   +  + +   V      T    EPP F+ +  
Sbjct: 538  YRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCV-----ATHLLKEPPTFVKKVD 592

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
            + T     T+ L A V  +   S+ W +  E+I     I  +F      L I +V   + 
Sbjct: 593  DFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISL- 651

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VST 958
             G Y C+A N AG  +    + +  E    ++  +   +   G    LE   S T  +  
Sbjct: 652  GGKYTCLAENEAGSQTSVGELIVK-EPAKIIERAE-LIQVTAGDPATLEYTVSGTPELKP 709

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVV 1012
            KWY + + +       I  +              D G     + ++      ET+  ++ 
Sbjct: 710  KWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 769

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
            ++  P F + L++ +        L+ +I  S    V W +DG+ +    ++Y        
Sbjct: 770  RDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKEL-TASDRYQIAFVEGT 828

Query: 1072 RKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
              L I    ++D G ++C   +      ++   +V+ PP  +T+  ++ V  G+    + 
Sbjct: 829  ASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSRDVLPGSAVCLKS 888

Query: 1129 ELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNS 1183
                   L ++WFK   E+       +T +  +  L++Y     D+G Y+C+V    G+ 
Sbjct: 889  AFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSV 948

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF 1242
            +C+A L V+EP+  F  +L    L+       L  ++     + +TW+     + ++ K 
Sbjct: 949  ECSADLFVKEPA-TFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKH 1007

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR 1301
             +        L +     +D  EY C    +A S     + +V+  P      +   + +
Sbjct: 1008 KMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKESPYFTKEFKSIEVLK 1067

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
              DV LL +    P     W  ++  ++  +  K  +  +  SL + K    DAG Y+ R
Sbjct: 1068 EYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVAADAGEYQCR 1127

Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQ 1420
            + N  G +     VT+ + PS   K  I    S        +    G+  I + ++ +  
Sbjct: 1128 VTNEVGSSTCSARVTLREPPSFIKK--IEATSSLRGGTAAFQATLKGSLPITVTWLKDND 1185

Query: 1421 EI---DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            EI   D        N+     S   +K +  Y     A N+  I   S        +KE 
Sbjct: 1186 EITEDDNIRMTFENNVASLYLSGIEVKHDGKY--VCQAKNDAGIQRCSALLS----VKE- 1238

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533
                 T+ +   +I     +   L   F G  +    W++DG++L    K   +  +   
Sbjct: 1239 ---PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVS 1295

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-V 1592
                          Y     ND G       + +    +     + +++   +   ++ +
Sbjct: 1296 ILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDL 1355

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
              ++ G  P  + W+K+  ++    ++  +  + T+ + I +L+ + S  YT  A+N AG
Sbjct: 1356 ECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 1415

Query: 1653 TSSVEVTLKVYDKPSKPEGP 1672
             S     L V + P   E P
Sbjct: 1416 HSQCSGHLTVKEPPYFVEKP 1435



 Score =  184 bits (447), Expect = 3e-44
 Identities = 172/703 (24%), Positives = 305/703 (43%), Gaps = 52/703 (7%)

Query: 632  IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            IPP+F+KK      + EG+   LE R+       +AW     EI P  N  +  +++   
Sbjct: 4908 IPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNN--- 4964

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               +L++        G YT  A N  G A     + IK   K+PP   + L  +   +G+
Sbjct: 4965 -ALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKE-PKKPPVFDQHLAPVTASEGD 5022

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808
            SV LS  V G+    I W K  + VK     S        +L+ K+    D G Y  KA 
Sbjct: 5023 SVQLSCHVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKAS 5082

Query: 809  NSEGIAETSAVITVEE-----PTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNP 860
            N  G   +   +T++E     P  + A       F++  Q I V EK T   +A+V  +P
Sbjct: 5083 NVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 5142

Query: 861  VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            +P++ W +     ++    I  +  G+  +L I +  ++ DSG Y+CVA N  G+     
Sbjct: 5143 IPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDT-TKTDSGLYRCVAFNKHGEIESNV 5201

Query: 920  RVTIDV----EKVT--FVKHLQKSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGM 970
             + +D     EK+       L+K+   ++G     E         V  K Y     + G+
Sbjct: 5202 NLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGI 5261

Query: 971  -DHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLVV----KETIPEFIRKLQ 1024
             D R ++Q                ++  ++   +D++    LV     + T  E +  ++
Sbjct: 5262 TDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTLIK 5321

Query: 1025 DFE----VKEKDVAI-LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
            D E    +K+ D    ++++IN     + W +  E ++P  NKY+    G    L ++N 
Sbjct: 5322 DIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPS-NKYEISIDGDRHTLRVKNC 5380

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRW 1139
               D+G Y  +      +A++TV+E  P     LQ+  + +G   T   + +  +    W
Sbjct: 5381 QPKDQGNYRLVCGPHIASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEW 5438

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199
            F++G  ++    ++  ++ K  KL I D   +D G+Y+C+  + + +A L +E   I FT
Sbjct: 5439 FRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQGQYTCKHEDLETSAELRIEAEPIQFT 5498

Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
             R+ + I+V  +  A    E+  +   VTWYK  + + +++K+   +D +   + I   T
Sbjct: 5499 KRI-QNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVT 5557

Query: 1260 EDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292
             DD+  Y+ +       +A+ST +L +   E      PP I D
Sbjct: 5558 PDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPD 5600



 Score =  144 bits (350), Expect = 2e-32
 Identities = 159/671 (23%), Positives = 268/671 (39%), Gaps = 31/671 (4%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P   R+++  EV    +A    EI  +      W + G  I  + +K       ++  L 
Sbjct: 117  PVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIY-ESDKCSIRSSNYVSSLE 175

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVEL-PPEIITRLQNQKVNKGNKATFEIEL 1130
            I  T V D GEY+C   +E    SCTA +TV E  PP  ++R +      G  A F   +
Sbjct: 176  ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTV 235

Query: 1131 TKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----C 1185
            +    + + W KDG+ +  S   ++T    K  L++ +  + D G YSC+  N      C
Sbjct: 236  SGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADIC 295

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244
             A LT+ +   +F   L E +    N   +L  ++  D  + +TW K    +   + + +
Sbjct: 296  QAELTIIDKP-HFIKEL-EAVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKI 353

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRG 1302
              + K  +L I      D   YTC    +A S++      V  PP  V   +  Y +  G
Sbjct: 354  YFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPG 413

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
                L    +  P     W  N+K + +    + S  +  A L I  V+  D+G Y    
Sbjct: 414  ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEA 473

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
             N+ G       V I + PS        +I   +  +   E   TG   + ++  + ++I
Sbjct: 474  TNDVGSDSCSTEVVIKEPPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFK-DKKQI 532

Query: 1423 DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
             +++    K    TQ +   L+ +S   F +  V + +   A+E  +   V      + P
Sbjct: 533  RSSK----KYRLFTQKTFVYLEISS---FNSADVGDYECVVANEVGKCGCVATHLLKEPP 585

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXX- 1538
            T  K + + T    + + L     G     V W +  + +K     K ++ N        
Sbjct: 586  TFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIP 645

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                     Y C+A N+ G  +TS    I ++P   I   ++ Q    GD   +   + G
Sbjct: 646  DVQISLGGKYTCLAENEAGS-QTSVGELIVKEPAKIIERAELIQV-TAGDPATLEYTVSG 703

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             P  +  WYK+G  L   K+Y I+ K   + ++    +   S +YT E SN  G+SS E 
Sbjct: 704  TPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCET 763

Query: 1659 TLKVYDKPSKP 1669
            T  V D+   P
Sbjct: 764  TFTVLDRDIAP 774



 Score =  143 bits (346), Expect = 5e-32
 Identities = 212/968 (21%), Positives = 373/968 (38%), Gaps = 99/968 (10%)

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAI 684
            A IL   PP F K+ +   V  G    L+C+L   PE  ++W +KG+ ++ P     +  
Sbjct: 4614 AQILILEPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSW-YKGDTKLRPTATCKMHF 4672

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
            ++++    + L  T V     G Y   A N  GE S    L ++  +K PP     L+ +
Sbjct: 4673 KNNV----ATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQE-QKLPPSFSRQLRDV 4727

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGV 802
                G  V+    V G+   +++W K+ KP+K  P        +I  L   K      G 
Sbjct: 4728 QETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQ 4787

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y+  A N  G A + A + +     E   PP F      +      +  L   VT     
Sbjct: 4788 YSCTATNPIGSASSGAKLIL----TEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPI 4843

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             +TW ++N  I        ++   +  L I  VD   DSG Y C A N  GK S  A++ 
Sbjct: 4844 KVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKG-DSGQYTCYAVNEVGKDSCTAQLN 4902

Query: 923  IDVEKV--TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978
            I    +  +F K L ++ E  EG +  LE +   S  ++  WY N  EI    + EI+ +
Sbjct: 4903 IKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFK 4962

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQETSTM----LVVKE--TIPEFIRKLQDFEVKEKD 1032
                          D G+  C   +   S +    +V+KE    P F + L      E D
Sbjct: 4963 NNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHLAPVTASEGD 5022

Query: 1033 VAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-- 1089
               L   +  SE   + W + G  +KP  ++  F        L ++ T+  D G+Y C  
Sbjct: 5023 SVQLSCHVQGSEPIRIQWLKAGREVKP-SDRCSFSFASGTAMLELKETAKADSGDYVCKA 5081

Query: 1090 --ILRDESCTAEVTVVELPPE--------------IITRLQNQKVNKGNKATFEIELTKG 1133
              +   ++   +VT+ E P                 ++  Q+ +V +   ATF I    G
Sbjct: 5082 SNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF-IAKVGG 5140

Query: 1134 DAL--VRWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCT 1186
            D +  V+W K    ++     I +   G + KL+I D    D+G Y C    + G  +  
Sbjct: 5141 DPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESN 5200

Query: 1187 AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL-- 1244
              L V+E      +   +   +   T A       +E +D+    K    ++ EK+    
Sbjct: 5201 VNLQVDERKKQEKIE-GDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMY 5259

Query: 1245 -ISDVK---KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDYEREYR 1298
             I+D +   +   ++++  E++        L+     + + E  V     ++   E    
Sbjct: 5260 GITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTL 5319

Query: 1299 IKRGSDVTLLVDYQA---------FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
            IK   + T+L D  A         +P+    W   ++ ++     + SID    +L +K 
Sbjct: 5320 IKDIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKN 5379

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
             +  D G Y+L     CG       +T+++   P  + ++ ++       C         
Sbjct: 5380 CQPKDQGNYRL----VCGPHIASAKLTVIE---PAWERHLQDVTLKEGQTC--------T 5424

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT- 1468
             T  + V   +    +EW     + K Q  +   KT   ++     + +V   D  + T 
Sbjct: 5425 MTCQFSVPNVK----SEWFRNGRVLKPQGRV---KTEVEHKVHKLTIADVRAEDQGQYTC 5477

Query: 1469 --EYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-K 1523
              E  +   E +I++  ++  K ++NI    ++     C         VTWY+   +L +
Sbjct: 5478 KHEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTE 5536

Query: 1524 TAKATYEN 1531
            + K  + N
Sbjct: 5537 SQKYNFRN 5544



 Score =  123 bits (297), Expect = 5e-26
 Identities = 138/604 (22%), Positives = 244/604 (40%), Gaps = 46/604 (7%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E    P+F + L P    +G +VQ  C V+G    +I W +    +KPS D   +    
Sbjct: 5001 KEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPS-DRCSFSFAS 5059

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXX 622
              A L ++E    D+G + C A N AG  +S  ++ I E P +   ++            
Sbjct: 5060 GTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAA--------- 5110

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENIS 681
                  ++G    F  +P++  V E +      ++   P P++ W   K  ++     I 
Sbjct: 5111 ------VDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIL 5163

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            +  + D     + L+I +  K   G Y  VA N+ GE    + L++   +K+  ++   L
Sbjct: 5164 IHQKGDE----AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQ-EKIEGDL 5218

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKP----KK 796
            ++M+ +     +            +   KN  P +     +  G T    +L+     K+
Sbjct: 5219 RAMLKK--TPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQ 5276

Query: 797  VKDEGVYTLKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIK 851
             ++E  + L+ E  E       E   ++   +      EP   I   +  TV K+   I 
Sbjct: 5277 SQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTLIKDIENQTVLKDNDAIF 5336

Query: 852  LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
             +      P   ++WY+  E + PS     + DG+   L + N   + D G+Y+ V    
Sbjct: 5337 EIDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKNCQPK-DQGNYRLVC--- 5392

Query: 912  AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGM 970
                 H A   + V +  + +HLQ     +EG+T  + CQ S   V ++W+ N + +   
Sbjct: 5393 ---GPHIASAKLTVIEPAWERHLQ-DVTLKEGQTCTMTCQFSVPNVKSEWFRNGRVLKPQ 5448

Query: 971  DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
               +   E +            D G   C  +D ETS  L ++    +F +++Q+  V E
Sbjct: 5449 GRVKTEVEHKVHKLTIADVRAEDQGQYTCKHEDLETSAELRIEAEPIQFTKRIQNIVVSE 5508

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
               A  E E++ + A V W + G     +  KY+F   G    + I N +  DEG YS I
Sbjct: 5509 HQSATFECEVSFDDAIVTWYK-GPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVI 5567

Query: 1091 LRDE 1094
             R E
Sbjct: 5568 ARLE 5571



 Score =  107 bits (258), Expect = 3e-21
 Identities = 129/599 (21%), Positives = 240/599 (40%), Gaps = 34/599 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            P I  R++  +V  G+ A F  E+ +G   VR  WFK G EI  S+   +        L+
Sbjct: 117  PVIKRRIEPLEVALGHLAKFTCEI-QGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLE 175

Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA-YLTVE 1219
            I    + D GEY+C    E G+  CTA LTV E      L  P+ +       A +L   
Sbjct: 176  ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTV 235

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT 1277
                 +++ W K  + +  +    +     K +L +   T  D+  Y+C   +       
Sbjct: 236  SGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADIC 295

Query: 1278 KLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            + ++ +++ P  I + E  +  I +   +   VD     +    W  + + +   K  K 
Sbjct: 296  QAELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDR--KVTITWSKDGQKLPAGKDYKI 353

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDS 1394
              + K ASL I   +  D+G Y     N  G +     V + + PS   K  P+ L +  
Sbjct: 354  YFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPG 413

Query: 1395 SSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFR 1452
             S  +     +  G+  I + +    +E+  +  + +  + ++    I ++K + S  + 
Sbjct: 414  ESARL---HCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYS 470

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A N+V  SD+  T     VIKE     P+  K L+        +  L C   G    +
Sbjct: 471  CEATNDVG-SDSCSTEV---VIKEP----PSFIKTLEPADIVRGANALLQCEIAGTGPFE 522

Query: 1513 VTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            V W++D K+++++K     T +                 Y+C+  N+ G+        ++
Sbjct: 523  VNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCVATHLLK 582

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
            + P      +D       G    + A + G  P  V+W K    ++ D +  ++     +
Sbjct: 583  EPPTFVKKVDDFTAL--AGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVA 640

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
            V+ I +++ S   KYT  A N AG+ +    L V +     E   +++  + +  T+E+
Sbjct: 641  VLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 699



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 46/120 (38%), Positives = 62/120 (51%), Gaps = 5/120 (4%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
            G+ A FE  ++   A+  W KDGS I+ S   +   DGK +KL I D  L DAGEY+C  
Sbjct: 8126 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVL 8185

Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
             +GN +   TA L VEE  + F   L E + V      YL+ E+  E  DV W K   ++
Sbjct: 8186 RLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIV 8244



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 32/87 (36%), Positives = 53/87 (60%), Gaps = 1/87 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV +L P     G +V  +CQV G P   ++WF+    ++ + +++ Y+  +NVATLV
Sbjct: 2740 PYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYF-TNNVATLV 2798

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTT 596
              +V   D+G +TC+A+N+ G A+S T
Sbjct: 2799 FNKVSINDSGEYTCMAENSIGTAASKT 2825



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 50/162 (30%), Positives = 82/162 (50%), Gaps = 12/162 (7%)

Query: 1018 EFIRKLQDFEVKEKDV----AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            +F+++++D  + E +     AI E  ++  TA   W +DG  I+ +  K+ F   G  RK
Sbjct: 8109 KFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIR-ESPKHRFIADGKDRK 8167

Query: 1074 LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEI 1128
            L+I +  + D GEY+C+LR    +++ TA++ V ELP   +  L+ +  V KG       
Sbjct: 8168 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSC 8227

Query: 1129 ELTKGDALVRWFKDGS-EIQFSNHIQLTIDGKKQKLKIYDCD 1169
            EL K   +V W KDG   ++    I   + G  + L I D D
Sbjct: 8228 ELNKERDVV-WRKDGKIVVEKPGRIVPGVIGLMRALTINDAD 8268



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 2/95 (2%)

Query: 510  PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P F++KL   K    G ++Q EC++ G P  ++ WFR  + +  S  + M + + +VA L
Sbjct: 3025 PKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVN-SVALL 3083

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             I E   ED G + C A N  G AS +T L V+AP
Sbjct: 3084 TINEASAEDTGDYICEAHNGVGDASCSTALKVKAP 3118



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 60/274 (21%), Positives = 108/274 (39%), Gaps = 14/274 (5%)

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            + ++I    + ++WYK    +E + K+ +  D  + TL ++ C   DQ  Y  V      
Sbjct: 5338 IDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKNCQPKDQGNYRLVC--GPH 5395

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
                K+ V+E  P    + ++  +K G   T+   +   P    EW  N +++K     K
Sbjct: 5396 IASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRVLKPQGRVK 5452

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDS 1394
              ++ K   LTI  V   D G Y       C H D+E +  +  +  P      I  I  
Sbjct: 5453 TEVEHKVHKLTIADVRAEDQGQY------TCKHEDLETSAELRIEAEPIQFTKRIQNIVV 5506

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRA 1453
            S       E E + +  I+ +     E+  ++  + +N  +    +I N+  +    +  
Sbjct: 5507 SEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSV 5566

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
             A  E    +A  T E Y   KE K++    + P
Sbjct: 5567 IARLE-PRGEARSTAELYLTTKEIKLEMKPPDIP 5599



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+ + P F  +L+      G  V   C++ G    Q+ W+R   +++  ++ QM +  D
Sbjct: 2830 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSF-VD 2888

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            NVATL I +     +G ++C A N  G ASST  L    P
Sbjct: 2889 NVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREP 2928



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 31/101 (30%), Positives = 54/101 (53%), Gaps = 1/101 (0%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           ++ +AP+F + LR   +  G   + +C++ G    +++WF+    +  S  +Q+ + +  
Sbjct: 769 DRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVE-G 827

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            A+L I  V   DAG FTC A N+ G   S+  LIV+ P S
Sbjct: 828 TASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 868



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 1/99 (1%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T +EQ + P F  +LR      G  V FEC V G     ++W++    +K S + Q  + 
Sbjct: 4710 TVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSF- 4768

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             DN+ATL I +     +G ++C A N  G ASS  +LI+
Sbjct: 4769 LDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLIL 4807



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV++  P     G  + F   + G P  ++ WFR    +       +Y+ +D VA L 
Sbjct: 2554 PSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYF-EDTVAELE 2612

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDHGSE 610
            +  +    +G +TCV  N AG AS TT L V+ P      LSDH  E
Sbjct: 2613 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPATFVKKLSDHSVE 2659



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            ++ + P F  +L+      G++   EC+V G     I WF +   I     +Q  + D N
Sbjct: 2456 DRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSD-N 2514

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            V TL +  +   D G++TCVA N AG       L V+ P S
Sbjct: 2515 VCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPS 2555



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 3/130 (2%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV 533
            +D+ +  QY    +NE + K     +   +E+ + P F +KL       +G++ + E +V
Sbjct: 4876 VDKGDSGQYTCYAVNE-VGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRV 4934

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G     + W++    I P+ + ++ + + N   L ++     DAG +TC A N AG A 
Sbjct: 4935 AGSQPITVAWYKNNVEIHPTSNCEIMFKN-NALLLQVKRASMADAGLYTCKATNDAGSAL 4993

Query: 594  STTELIVEAP 603
             T+ ++++ P
Sbjct: 4994 CTSSIVIKEP 5003



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 1/96 (1%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           E   AP+   ++ P     G   +F C+++G P  +  WF+    I  S D       + 
Sbjct: 112 EMKAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYES-DKCSIRSSNY 170

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           V++L I      D G +TC A N  G  S T  L V
Sbjct: 171 VSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 206



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 2/99 (2%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           ++  P F+ + +   T  G   +F C V G P  +I W +  A + PS D ++  D DN 
Sbjct: 208 EAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRV-TDADNK 266

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
            +L +  +  +D G ++C A N  G      EL I++ P
Sbjct: 267 HSLELSNLTVQDRGIYSCKASNKFGADICQAELTIIDKP 305



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568
            P FV+KL    T  G  V+ +  VEG+    + W +    +I+ S++ ++ + D N+ATL
Sbjct: 3212 PRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVD-NIATL 3270

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             +       +G + C  KN AG    +  L V  P
Sbjct: 3271 QLGSPEASQSGKYVCQIKNDAGMRECSAVLTVLEP 3305



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            +Q + P F +KL       GS++  EC+V G       WF+    I  S  +++    +N
Sbjct: 1893 DQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC-HEN 1951

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
              +L +  +  ED   +TC   N AG  + +  L V+ P S
Sbjct: 1952 TVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPS 1992



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            + +EK        G T   EC+V G P   + W++   ++  SQ  +  +  + +++L I
Sbjct: 2366 VIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLKI 2424

Query: 571  REVFPEDAGTFTCVAKNAAGFASST 595
              V  EDAGT+T   +N  G +S T
Sbjct: 2425 LSVEKEDAGTYTFQVQNNVGKSSCT 2449



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568
            P F+ KL       G   + +  +EG     + W ++   +I+ S++ ++ + + NVATL
Sbjct: 2271 PKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVN-NVATL 2329

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613
               +V P +AG + C  KN  G   +   L V  P  + +    MTV
Sbjct: 2330 QFAKVEPANAGKYICQVKNDGGVRENMATLTVLEPAVIIEKAGSMTV 2376



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 1/102 (0%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T+ E   +P F  K        G +  FEC V G    ++TW +    I+P  ++ +   
Sbjct: 2924 TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITC- 2982

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              N   L I +V   D+G +TC A N  G    + +L V+ P
Sbjct: 2983 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3024



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 42/163 (25%), Positives = 68/163 (41%), Gaps = 9/163 (5%)

Query: 1196 INFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            + F   + + +L  A +    A     +   T   TW K  S I ++ K   I+D K R 
Sbjct: 8108 LKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 8167

Query: 1253 LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLV 1309
            L I      D  EYTCVL   + + T+  K+ V E P + V   E E  + +G  + L  
Sbjct: 8168 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSC 8227

Query: 1310 DYQAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVE 1351
            +     + +  W  + KI ++K     P +     +LTI   +
Sbjct: 8228 ELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDAD 8268



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 4/139 (2%)

Query: 830  AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886
            A P  F+   ++I + E  ++    +     +P  +IT W ++   I  S       DG+
Sbjct: 8105 AVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGK 8164

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            + +L I +V    D+G+Y CV      + +  A++ ++   V FVK L++     +G+ +
Sbjct: 8165 DRKLHIIDVQLS-DAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPL 8223

Query: 947  ILECQTSHTVSTKWYHNKK 965
             L C+ +      W  + K
Sbjct: 8224 YLSCELNKERDVVWRKDGK 8242



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 55/245 (22%), Positives = 92/245 (37%), Gaps = 22/245 (8%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXX 1538
            P  E+ L+++T +  +   +TC F  VP  K  W+R+G+ LK     K   E++      
Sbjct: 5406 PAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTI 5464

Query: 1539 XXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
                      Y C     H ++ETS  + I+ +P+         Q   V +    T   E
Sbjct: 5465 ADVRAEDQGQYTC----KHEDLETSAELRIEAEPIQFTKRI---QNIVVSEHQSATFECE 5517

Query: 1598 -GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI--------EAS 1648
                   V WYK   +L   ++YN     +   + I  +       Y++        EA 
Sbjct: 5518 VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEAR 5577

Query: 1649 NTAGTSSVEVTLKVYDKPSK-PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
            +TA        +K+  KP   P+  V +  +   +V  E  PP     + L     E+ +
Sbjct: 5578 STAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKK 5637

Query: 1708 PDNNR 1712
            P   R
Sbjct: 5638 PPAKR 5642



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 22/97 (22%), Positives = 44/97 (45%), Gaps = 1/97 (1%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            +P F ++ +         V    +V G P  +ITWF+    ++  + ++ +  D  V+  
Sbjct: 1053 SPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQ 1112

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            V++ V   DAG + C   N  G ++ +  + +  P S
Sbjct: 1113 VLKFV-AADAGEYQCRVTNEVGSSTCSARVTLREPPS 1148



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 17/48 (35%), Positives = 28/48 (58%)

Query: 168  PDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK 215
            P V++PP+  + E K+ P ++++ E P AK  E+  E P +  VP  K
Sbjct: 7692 PKVTEPPKKPVPEKKAPPAVVKKPEPPPAKVPEVPKEAPPEKKVPPKK 7739



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F +K  P     GS V  +C++ G P  ++ W +    ++ S+ F++   + + +  +
Sbjct: 3119 PVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLHI 3178

Query: 570  IREVFPEDAGTFTCVAKNAAG 590
                 P D G + C A N  G
Sbjct: 3179 FNLEAP-DIGEYHCKATNEVG 3198



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 49/238 (20%), Positives = 93/238 (39%), Gaps = 20/238 (8%)

Query: 170  VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSK 229
            V + P+  I E K    L+++ E P  K  +    VP  + +P ++E  + P       +
Sbjct: 6737 VPEVPKKPIPEEKKPTALLKKMEAPPPKAPKKREVVPVPVALPREEEEEEVPFEEVPEEE 6796

Query: 230  LTP---IKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRI 286
            + P   +  E +      P   E V   +               E    +    ++K ++
Sbjct: 6797 ILPEEEVPSEEEAPPEEVPPEEEEVLPEEEEVLPEEEEVLPEEEEVQPEEEALPEIKPKV 6856

Query: 287  KYITSWPPESIK-PLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL---- 341
                  P    K P    +   K+    ++  + + KV+++  +PPK  +V   E+    
Sbjct: 6857 PKPAPVPEIKKKVPEKKVVVPKKEEAPPTKVPEVSKKVEERRIIPPKEEEVPPAEVYEEA 6916

Query: 342  ----------EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSA 389
                      E P    E+IVE +++E E++  +    E+ K+ VPE  T  P+K+ A
Sbjct: 6917 EEPTPEEIPEEPPSIEEEEIVEEEEEEEEVLPPR--APEVVKKAVPEAPTPVPKKAEA 6972



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 524  GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            GS+  FEC V   P   IT W +  + I+ S   +   D  +   L I +V   DAG +T
Sbjct: 8126 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYT 8182

Query: 583  CVAKNAAGFASSTTELIVE 601
            CV +      +ST +LIVE
Sbjct: 8183 CVLRLGNKEKTSTAKLIVE 8201


>UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; n=12;
            Caenorhabditis|Rep: Muscle M-line assembly protein unc-89
            - Caenorhabditis elegans
          Length = 8081

 Score =  266 bits (652), Expect = 5e-69
 Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%)

Query: 460  KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506
            +H+ E+KG   +  L+  D NN     YT     K   +E + +L +    FEK T+EE 
Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
             + P+F+E L+     +G TV  EC+V     PQI +F+    ++  Q  Q+   +D   
Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620
             L I+    ED G + C A N AG A++  +L       VE  ++D   ++         
Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802

Query: 621  XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
                 +    G   P F +  ++  V E    +L+C++   P P I W  +G+E+     
Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862

Query: 680  ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734
            +    + D  +    L   NV +   G Y   A N  G A    PI++ ++   K   E 
Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790
            P  ++P+K  +V  GE+ +L  ++ G P+P++ W KN    KP   +  ++ D  T  +T
Sbjct: 3920 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            +    K+ D   Y  +A N  G   +   +TV+EP +     P F      I VKE  T 
Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            K   +V+    P + W+++   +   + +  ++ D     LVI +  ++ D G+Y+   S
Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093

Query: 910  NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968
            N AG ++    +T+   +   +K         +G  ++L  +      T KWY   + ++
Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153

Query: 969  GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018
                 +I+Q                D G  + ++       + ++T+ V K     ++P 
Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077
            F + L D  V +    +LEVEI  +  DV W ++G+ IK  K     E  G+ + +L I 
Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
            +    D GEYS    +E+   E      V   PEI++ L    V +G  ATF +++    
Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190
              V+W+K+G EI  +   +   DG    L+I +  ++DA +Y    S + G++  +A LT
Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387

Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
            V+          PE +  L+P        A   V++      V WYK    I + +    
Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302
             +     +L I     DD  +Y  V+  DA          V+ P   IV    +  + +G
Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361
                L V+    P+   +W  N K I      +P  D      L I    + DA  YK+ 
Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564

Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416
            L +  G+ AD    +T+     P  +P I++ ++   ++I      E E +G+   + + 
Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
               +E+      ++K I K   +   L+  SS             ++A       K+  E
Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531
             KI   T  KPLK+ +    E+ E +      P+  V WY++G+++K       +   + 
Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587
            +               YK +  N  GE E+S  + +++       I    ED  Q    G
Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
             + +    I+G  P +V W ++ N +       I   + T+  + I       + +YT+E
Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671
              N +G +  +   +V +KP    G
Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878



 Score =  248 bits (607), Expect = 1e-63
 Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ +    +VEG P+  + W++ T  +  SQ  ++    ++   L I      D G +  
Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            V         ST    VE+      + +TV                    P+F K    Q
Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             V +G+ ++LE  +   P+ D+ W   G+EI  D  +      D+      L I + ++ 
Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
              G Y+V A N  GE    I  K K      P+++  L    V+QGE+   + +V G P 
Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
              + W KN K +    TK +GD      +   +V+D   Y +   N  G A++SA +TV+
Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389

Query: 824  EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
               + ++   P  ++     TVK+  T     +V + PV  + WY+N + I P+     N
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             DG +  L I N   + D+ DYK V SN AG +   A +T+ +  +  VK L+ + E  +
Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504

Query: 943  GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000
            GK  +L+ +T+      KWY N KEI+  D  +   +G              D    K +
Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564

Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053
            + D++ +T      L VK     P+ I+ L+D  V       LE+E +     V W ++G
Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624

Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109
            + +     K    ++    K  L I ++ V D G+Y   + +E+ +A  +  + + P+I 
Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684

Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166
             +  L++Q + +G  A F +E      +V+W+K+G EI+ ++   I+   D K Q L I 
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743

Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220
            +   DDA  Y   +    G ++ +A LTV++        ++  E  +V         V+I
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
              E  DV W +  +VI       +  I D   R LII      D  EYT  +++   K+ 
Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            +  K EV E  P+IV       I  G D    V+  A P    +W  N + IK   H + 
Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920

Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
              I  K   L I + +  D   YK+ L N  G  D    +T++       KPN+L+I   
Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973

Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
              ++  +EP+         G   +I +    QE+   +    K   K ++   +L   SS
Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032

Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503
             +    A   V  +D  E      V +K  K   PT       PLK+   E  + + L C
Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092

Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
               G P P+V W +DG  L+     T +   +                 Y+  A N+ G 
Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 5152

Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611
              + C V + +      KP   I    +K    + GD+      + G+P P + W+ NG 
Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 5209

Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
             ++ D    +    +    + I++++          A N  GT
Sbjct: 5210 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252



 Score =  246 bits (603), Expect = 4e-63
 Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V +G+ ILL   +   P+  + W +KG E V     +  ++     Y   L+I + +   
Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179

Query: 705  EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
             G Y VV + +     S   V   K  EK   P   + L    V +G  ++L  ++ G P
Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239

Query: 763  RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            +  + W KN   +K    +  G+      +   + KD G Y++ A N  G  E+ A + V
Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
                  +A+P + ++     TVK+  T     +V + PV  + WY+N + I  ++T   N
Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935
             DG +  L I N   E D+ DYK V SN AG +   A +T+       D  K   V  L 
Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407

Query: 936  KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
             +   ++G+T     +    V   KWY N KEI     ++                  D 
Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464

Query: 995  GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
               K +V     D ++S  L VK      ++ L+D EV +   A+L+VE N +  ++ W 
Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103
            ++G+ I P           +  +L I +    D  EY  +L DE       SC   V + 
Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160
               P+II  L++Q V+ G+    EIE +     V+W+K+G E+    +  I++  ID  K
Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644

Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
              L+I    ++D G+Y  EV    G++  +  +TVE P I F   L +  +     +A  
Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271
            +VE   +   V WYK    I+   +F +      K  L+I+    DD   Y  VL     
Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762

Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            +A+S+ +L V+  +    KIV    +  + +G+ +   V  Q  P+ +  W+ ++ +I  
Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821

Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
              +     ID  +  L I   +  DAG Y + + N  G A  +    + +KP        
Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447
            +EI     ++   + E +     + +    QEI     +  K I   K + +I   + + 
Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
               ++    N     D+S       V+K   ++   +   LK++  E  + +EL     G
Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993

Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            +P+  + WY++G++LK     ++                        Y+ +  ND GEV 
Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052

Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            +  VV ++  K     S  +     K      GD   +   I G P PEVIW K+G  L+
Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112

Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670
             D    +    + T+ +RI+  K+S   +Y + A N AG  TS  +VT+ +  ++PSKP+
Sbjct: 5113 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 5172



 Score =  218 bits (533), Expect = 1e-54
 Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+E L       G+ V  +    G P+P +TW+     I  S D      DD  +TL 
Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812

Query: 570  IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626
            I    P+   G   C A+N AG  S T  +I       S+  SE               +
Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872

Query: 627  --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
              + +   P     P F  K K     +G   + EC +         WL  G+EI     
Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932

Query: 680  ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733
            I V   +    + +  L + NV     G YT +  N  G    EA+L ++  + K  EK+
Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791
             P+ I  L+    +  E V+L  +V+G P+P ++W  +NK +  +++  +S      +TI
Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849
                ++  +G YT  AEN+EG ++T A +TV+       E P+F    Q  E+++ EK  
Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103

Query: 850  IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901
            + L   V  +P P + +Y  +E       I+ S  I    D  N    +VI+ +  E D 
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960
              YK +A+NS G ++  +++T  VE   F + L+K+   +E + + +E +   +    +W
Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221

Query: 961  YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014
            + + K +S   + E+ +  E              D G       +     E+S    V +
Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281

Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070
            ++  P F+R+L   EVK  + A L V +       V W +DG+ ++   +    +  G  
Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341

Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124
               + I++  + D G+Y+C   +   E+ T A   VV+  +PPE + +L   +V +    
Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401

Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
            T  +++    +  V WFKD + I   N H IQ         L I D    D G YSC   
Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461

Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232
             E G +  TA   +   SI   FT +L P  +      D  +TV I     +V W+K  K
Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
               I+++  F         TL I++   +D   YTC       +AK+T  + V+     P
Sbjct: 3521 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346
              V   + Y +++G    L+V  +  P+P  +W  +   I    +H  +   ++ S +L 
Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640

Query: 1347 IKKVENTDAGIYKLRLENNCG 1367
            IK   N D G Y  +  N  G
Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661



 Score =  209 bits (511), Expect = 6e-52
 Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +E+  AP+FV+ L+P     G   +   +VEG P P++ WF+    I       +    +
Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633

Query: 564  NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
            N + TLVI++    D G +TC A N AG      E + E  +  +  E            
Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                   E + P F +  K  +  EG  ++LEC++     P I +    + +   +++ +
Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734

Query: 683  AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
             +  D ++    L I N KK   G Y   AVN  G+A+    LKI+   K    V +   
Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791

Query: 743  SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781
             +  + Q E+V                   +L +  V   +  I  CK   +P   +   
Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851

Query: 782  SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824
             +G    ++     + KD+G  TL               +AEN  G A T    ++T+E 
Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3911

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883
              + + E P F+   +   V    T  L  +++  P PS+ WY+N E + PS+ +  +N 
Sbjct: 3912 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940
            D     L +TN   + D  +Y+C ASN  G       +T+ +  +V   F K L  + + 
Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029

Query: 941  EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
            +E +T   EC+ S T    KW+ +   +      H E   +G             D G  
Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088

Query: 998  KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052
            +  +  D   +   V    +P    K    L D  V +    +L VE+  +   V W + 
Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106
             E +   +     +      KL I +  + D G Y  +L  +S + E    VTV +    
Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208

Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
               P     L +Q V KG     E+E+      V+W+K+G EI+    ++  +   K +L
Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217
             I D    D GEYS    N    A     +  +N + + PE +  LVP        A   
Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273
            V++      V WYK    I D +  T  +     +L I     +D  +Y  V+     DA
Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380

Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
             S+  L V++ +       P+IV       +K+G   T  V  +  P    +W  N K I
Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
               K  K + D  S SL I   +  D   YK+ + N+ G AD    +T+      PG   
Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493

Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443
            +  ++ + +        + E       I +    +EI  ++          K Q  I + 
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
              + +  ++    +E    D +       +  +   + P + K L++        I+L  
Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
               G P+  V WY++GK+L  A A         +N+               YK    N+ 
Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G   +S  + ++  P IT   + +K +     E    +V     P  V WYKNG +++ +
Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725

Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
              + I  K  T   + IK   R  +  Y I   NTAG   SS ++T+K
Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773



 Score =  202 bits (494), Expect = 6e-50
 Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V +G   +L+      P+ +I W   G+EI P +      + D       L I +     
Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557

Query: 705  EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
               Y VV  + +G  A     L +K   KEP ++I+ L+  +V  G  + L  +  G+P+
Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616

Query: 764  PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             T+ W KN K +     K +  +   D   +  +    V+D G Y ++  N  G A +S 
Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876
             ITVE P     +P     + Q IT  E         V  N  P I  WY+N + I P S
Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
              I +       +LVI N   + D+  YK V  N+AG++   A++T+   K    K + K
Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784

Query: 937  SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991
              E +   +G  ++ E +        +W  +   IS   +  I + +             
Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844

Query: 992  XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
             D G     V ++        K  +   PE +R L++ E+ E D  + +VE+++    V 
Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105
            W ++ + IKP  +  + +K G  + +L I    + D  +Y  +L + +  C +   +  +
Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963

Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159
             P   +I+  L++  V +      ++++     +++W+K+G E++        +   +  
Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214
            +  L I      D G Y   +GN K      +++ V+    +       F+    +T+  
Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083

Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267
                LT++  I  E   +V W K   V++  ++ T+ ++     TL IR   + D  +Y 
Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 5143

Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
                +    +T+  KV V E       PK V   +      G      V  +  P+P  +
Sbjct: 5144 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 5203

Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            W +N   IK   + T   +   +  LTI+ V   D G  K   +N  G  D  +      
Sbjct: 5204 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437
                 G  + L          WD     G+   I   V+       EW    K I  T  
Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480
            T I+N   + + R +     E DI             +ET   Y+V     ++E K +  
Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535
            +P +  PL++ T    + I L+C    +P+  V WY+DG  L+    T   YE       
Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587
                        Y+C+A N HG + TSC V ++  ++ V     E    K  V      G
Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646
            D + +   + G P PE+ WY+NG  L N     I T+ + +  + + E   S    Y  E
Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561

Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685
            A N      T  T+ V++ L   +KP   EG  P  + E+S  SV++
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608



 Score =  180 bits (439), Expect = 3e-43
 Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E+++  P FV KLR K   +G  + FEC+VEG+P P++ W      ++PS DF++ YD  
Sbjct: 642  EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622
              A L IR+  P+D G +T   +N  G   S  EL V+A P  +H               
Sbjct: 702  T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                     + P F    +    DEG ++  +  +   P P+I W   G+ +   E +  
Sbjct: 746  ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796

Query: 683  AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
              E  +   C +L I +V +  +G  T    NR G AS    LK++     PP   +PL+
Sbjct: 797  ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798
               V++  +V+    V G P PT+T+    K +K     +        + I+I      K
Sbjct: 852  DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
             +G    KA+N  G AE+ A +TVE+  EE+   P F+   ++ TVK          V  
Sbjct: 912  HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            NP P +TW+ N   +       +  +  N +  +T +DS   +G   C A N+ G+    
Sbjct: 972  NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029

Query: 919  AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
            AR V +  EK      FV+ L    ET +  TV+ E +       +  WY   +E+   D
Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
              EI +               D G I+ +  + E S     K T+
Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133



 Score =  177 bits (430), Expect = 4e-42
 Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            V+ L     P G     + +    P+ +I W++    I PS   Q   D DN   LVI +
Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
               +DA  +  V  +  G  +            D    +TV               L   
Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691
             P   K  + Q V  GS I LE      P+  + W   G+E+      ++ I+  D + Y
Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750
              VL+I +      G Y V   N  G A+    + +     EP    ++PLK   + +GE
Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698

Query: 751  SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            +   S +    PR  + W KN    KP      +   DT    ++K     D   Y +  
Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866
            EN+ G AE+SA +TV++      +    I +  E  V  KG  K+V  V     P  + W
Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812

Query: 867  YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
             R+  +IS  +  I +  D     L+I + D + D+G+Y     N +GK+   A+  +D 
Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984
            EK   V+ L+ + E  EG   + + + S  V   KWY N +EI    H E  + G     
Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929

Query: 985  XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038
                    D G     V+     D ++S  L VVK  + + +  L+D +V+E     L+V
Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095
            ++      + W ++G+ +KP  + + FE++    +  L I ++   D G Y  +L  D+ 
Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049

Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143
                 +VV +              ++ L++ +V +G+  T +  +  G+    V W KDG
Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108

Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193
              +Q  + I  ++ +DG    L+I      D G+Y     N      S C   +T   E+
Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 5167

Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244
            PS   F + L     +P +   + + V  +P  TL   W+     I+  ++ TL      
Sbjct: 5168 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 5225

Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
                 I DV++      KC    E+   E  C             + + +PP+      +
Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354
             RI  G  + +     A P    EW  + K I+   HT  + ++D  +  + I   E +D
Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344

Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
             G+Y     N  G A+ +    V IL+      +       +  +    D+  N G    
Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401

Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458
            +   V+     +  W    +     ++TSIQ        L  N S       +R  A N 
Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461

Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
                + S +       +E K   + P   K L ++  +  +   L C   G P P++ WY
Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521

Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568
            R+G+ L+    T      +                 Y+C A N HG+ +T     +Q   
Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581

Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
               +KP          ++ +S+  +   + +  E  VT    G+P P V W K+G  L  
Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637

Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
            D  +  + +    V  +RIK         Y   A+N  G+++ +  +++ D
Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688



 Score =  176 bits (429), Expect = 5e-42
 Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567
            AP+F + L+     +   ++ E +V G   P + WF+    +    + +M  + +  V T
Sbjct: 3188 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 3246

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            LV+++    DAG +T  A N AG    T E   EA ++                      
Sbjct: 3247 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 3282

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
             LE   PTF ++     V       L   +  +P+P + WL  G+ +  D +  +A    
Sbjct: 3283 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 3339

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
               Y   +K   ++    G Y   A N  GEA       +      PP+ +E L  + V+
Sbjct: 3340 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 3396

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802
            + ES  LS +VVG P P++ W K++ P+       +  ++   + S+TI   ++  D G+
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 3455

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y+ +A N  G A T+A   +      ++ PP F  + + + V+E+ T+ L   V   PVP
Sbjct: 3456 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 3511

Query: 863  SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            ++ W+++++ I+   S    ++    +  L I     E D G Y C A+N AG++   A 
Sbjct: 3512 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 3570

Query: 921  VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976
            + +  ++E   FV+ L K YE E+GK   +++  +       KW+ +   I+ +D++ +I
Sbjct: 3571 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 3628

Query: 977  Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
            +   E              D G   C   ++      V +  IP++  + Q  E    +V
Sbjct: 3629 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3684

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
              L +E   ET  V  E D  +++ K NK       H +  + +N    + G++  +   
Sbjct: 3685 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3737

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
            E    ++T+     E +   + + VN   KA    +L              +IQF+  ++
Sbjct: 3738 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3783

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
              +  +  +L       ++ G++   VG++  +   T    +  F + L     V     
Sbjct: 3784 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3833

Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271
            A L  ++  E    + W K+   +E + +      D    TL     T+ D  EY C   
Sbjct: 3834 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3893

Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321
            +   +   +  ++   E  PKI     D+ +  +   +  G    L       P+P+ +W
Sbjct: 3894 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3953

Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378
              N + +K     K  ++D  +  LT+   +  D   Y+    N  G   +DV + V   
Sbjct: 3954 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 4013

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437
             + +P     +  I          E + +G    + +  +   +   + +  ++    TQ
Sbjct: 4014 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 4073

Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494
               I++ KT+    +R    N+  ++++         +  T + S T  ++K L ++   
Sbjct: 4074 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 4125

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549
                I L+    G P+  V WY+  + + +++ T      E+                Y+
Sbjct: 4126 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 4184

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604
             +   D   VE+S  V +  K    IS    K     Q    G   ++   IEG  P +V
Sbjct: 4185 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 4242

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             WYKNG+++++ K  ++   +    + I + +     +Y++ A+N AG    +  + V  
Sbjct: 4243 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 4300

Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691
            KP    G  P  +++    +  ++ K P+
Sbjct: 4301 KPEIVSGLVPTTVKQGETATFNVKVKGPV 4329



 Score =  171 bits (417), Expect = 1e-40
 Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563
            MAP F+ K++      G +  FEC V         W +    I+     ++      +  
Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
                LV+  V PEDAG +TC+ +N AG  +    L V   L     +             
Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                      P F    + +       ++LEC+++  P+P ++WL   + I  +   S+ 
Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
            +ES   +    + IT+ +   +G YT +A N EG +     L   T + E P   + L++
Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792
              +  GE ++LS  V G+P+P + +   ++  K + TK              +TH   ++
Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
                 +D   Y   A NS G A +++ IT +       E P+F    ++ +VKEK  IK+
Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911
              +V     P + W+++++ +S         + E  +  ++    +  D+G Y   ASN 
Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267

Query: 912  AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
            AG  +SS  A VT  +EK TFV+ L     +  E  T+ +  +     S +W  + + + 
Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327

Query: 969  GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020
                  I  ++               D G   C   +     +  +   VVK  + PEF+
Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387

Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077
             KL   EVKEK+   L V+ + +    V W +D   I    N +  +K+  +    L I 
Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446

Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131
            +    D G YSC  R+E+     TA   ++   +PPE   +L+  +V +  + T ++++T
Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504

Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182
              G  +  V WFKD   I   N HI    +G     L I     +D G Y+C    E G 
Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564

Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237
            +K TA + V+E   +  F   L  +  V     A L V +  +   +V W+K      I+
Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286
            +        +    TL+I+     D  +YTC   +   K  T  +LK+    F       
Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683

Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344
              P  ++  +E     G  V L         P  ++  N + ++  +H +  + +  +  
Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            LTI+  +  D G Y+    N  G A+   ++ I
Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776



 Score =  169 bits (412), Expect = 5e-40
 Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            TF K  K Q + EG +          P   + W   G+EI P+    +  ++D   Y  V
Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            +K  N  +    TY +V  N  GEA     L +K  +    ++++ L+  +V +G  ++ 
Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799

Query: 755  SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
              ++ G P   + W ++   + A    +  K D  T+ + I+    +KD G YT++  N 
Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G A++ A   V+E  E        +   + I + E         V+  PV  + WY+N+
Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909

Query: 871  EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            + I P+  +     G +  EL I     + D  DYK V SN+AG     A +T+    V 
Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968

Query: 930  FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984
             +    K  + EE + V L+ +        KWY N +E+     G    E  + G     
Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028

Query: 985  XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033
                    D G  + ++   K +  S  +V     K + P     F+  L+D EV+E D+
Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087

Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
              L+  I  E   +V+WE+DG +++                L IR+    D G+Y    +
Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 5147

Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142
            +E+ +A    +VTV E       P+ +  L+      G+K  F +++       ++WF +
Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 5207

Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193
            G  I+F + I L    DG    L I D   +D G   C   N   T     E       +
Sbjct: 5208 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244
                  LR P    VP   D  + V  P         + T +V W+K    IE T    +
Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325

Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290
             + V     I I    E D   Y CV ++    A++    +VE++E         + PKI
Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349
                 +  +  G  + L     A P+ +  W  +   ++    T    +   +A+L I  
Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
                D G Y+    N  G  +   +V +        K       +  +   W +    G+
Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502

Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455
            S  +   V        +W      ++N  +T  +TS     +L  N S       +R  A
Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509
             N    +    T      + +T+       KP      L +++      I+L C   G+P
Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622

Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561
             P V W +DG  L + ++  + N                     Y+C+A N++G   T  
Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682

Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
                     S VV   Q P  T+   D++     G    +   ++  P PE++WYK+G  
Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740

Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +       I+ + +  + + I          Y + A+N +GT+  + T  V   P
Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795



 Score =  156 bits (379), Expect = 5e-36
 Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F++ L+ +   +G   +F  +    PR  + W++    IKP+  F +    D    LVI+
Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
                +DA T+  V +N AG A S+ +L V+                          I++G
Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +        + Q V +G+ ++ E ++   PE D+ WL     I    N ++  + D   Y
Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              ++   ++K    G YTV  +N  G+A        K    E P+++  L+++ + +G+ 
Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
             +   +V   P   + W KN++ +K    L  K  G       +   ++ D   Y +   
Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N+ G  ++SA +TV +P          ++  +++ V+E   ++L  +V   P   I WY+
Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002

Query: 869  NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926
            N + + P ++        E+ E  +T   S+  D G Y+ V  N  G+   G+ V +   
Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062

Query: 927  K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975
            K         F+  L K  E EEG  + L+C  +     +  W  +   +   D     +
Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026
              +G             D+G  +   K++  S     K T+         P+F+  L+  
Sbjct: 5122 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180

Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
                 D     V++       + W  +G  IK   +   D    G+   L IR+    D 
Sbjct: 5181 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 5239

Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128
            G   CI ++E+ T E TV E                 PP     L ++++  G+    E 
Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298

Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181
             +     A V WFKDG +I+ + H ++  T+DG   ++KI   +  D G Y C    E+G
Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357

Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
             ++  A   VE              P IN  L   E   V       L+ ++       V
Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414

Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
             WYK    +  D+       +    TL I   TE+D   Y CV  +A  T      V V+
Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474

Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334
             P + V  E E              RG   TL       P P  +W  N ++++    T 
Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534

Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386
             + S D  S SLT+ +   +D GIY+   EN  G A       V+M +   +KP    GK
Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593

Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437
            P   ILE+   S+   N+   E + TG  N ++ +       I+ +  EW +  +    Q
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490
              I+N   +    +R  A NE    + S TT+ +  + +       T  Q P     + +
Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            + T   + ++L C     P P++ WY+DG
Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738



 Score =  149 bits (361), Expect = 8e-34
 Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            S E +    F+  L+     +G  +  +C + G P P++ W +   +++      M    
Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
            D  ATL IR     D G +   AKN AG A+S  ++ V    ++ G + +          
Sbjct: 5124 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 5169

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                       P F    K      G       ++  +P+P + W   G  I  D+ I++
Sbjct: 5170 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 5219

Query: 683  AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734
               +D + YC  L I +V++   GT   +A N  G        +   G  +        P
Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
            P+   PL    +  G+ + +   V  NP   + W K+ K ++    T+          +K
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336

Query: 794  --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846
              P +  D GVY   A N  G AET A   VE  E  EE       P      ++ TV  
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
               I+L  +V   P  S+ WY++   +      +  ++ +    +  N  +E D G Y+C
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956
            VA+N+ G  +    V + V K    K  ++ + T        + G +  L+C  +     
Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516

Query: 957  STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007
              KWY N + +     R +I+                 D G+ +C         K Q T+
Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575

Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055
               + + +T          P+FI +L D  V   +V  LE ++       V W +DG  +
Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101
            I+  + ++  E    + +L I+N +VHDEG Y C+  +E+ +A               V 
Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158
                PP    ++ + +  +G     E ++       + W+KDG+ +  S+ IQ+++  DG
Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
                L I  C  DD G Y     N   TA
Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783



 Score =  143 bits (346), Expect = 5e-32
 Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            + +  AP     L  K    G  ++  C+V+  PR  + W++    ++      + Y++D
Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
              ATL I +   ED G + CVA NA G  +++  + V+ P  +   E             
Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                   G  P F+K     + D G    L+C +   P P+I W   G+ +         
Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733
            IE+     CS L +       EG Y   A N  G+A          +L    K K  E +
Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
            PP+ I  L  M V  G  + L  +V G P P++ W K+  P+         ++       
Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653

Query: 791  I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845
            + +K   V DEG Y   A N  G A T + + +++         ++PP F  +  ++   
Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            E   +KL  +V  +P+P + WY++  I++PS+ I  +   + +  ++       D G Y+
Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773

Query: 906  CVASNSAGKSSHGARVTI 923
             +A+N +G +      T+
Sbjct: 5774 VIATNPSGTAQDKGTATV 5791



 Score =  141 bits (342), Expect = 2e-31
 Identities = 270/1279 (21%), Positives = 483/1279 (37%), Gaps = 84/1279 (6%)

Query: 151  VTLEKSDLFDSQEDESKPD-VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKI 209
            +T E  +   S + E  P+ V + P++  ++ KS  K I E  +   K  +   +V EK 
Sbjct: 1515 MTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574

Query: 210  NVPDDKETS-QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXX--X 266
              P  KE S + P S  K+S+   +K   K+ +       E +  P+             
Sbjct: 1575 ASPTKKEKSPEKPASPTKKSE-NEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKS 1633

Query: 267  XXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQ 326
                E S  K     +KS  K   S      KP                 +K   K +K 
Sbjct: 1634 PTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKS 1693

Query: 327  VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRK 386
                 + P     + + P  S  + V+S K+++    E++      KE  PE+      K
Sbjct: 1694 PQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVK 1753

Query: 387  SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446
            S  +K ++  ++   +K  +P +   +PV++   D V       + T +  +  + E   
Sbjct: 1754 SPTKK-EKSPEKSAEEKPKSPTKKESSPVKM-ADDEV------KSPTKKEKSPEKVEEKP 1805

Query: 447  ILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQ 506
               T  +     +K   EE    P +     ++ T+    +  EK  + P  EKP S   
Sbjct: 1806 ASPTKKEKT--PEKSAAEELK-SPTKKEKSPSSPTKKTGDESKEKSPEKPE-EKPKSPTP 1861

Query: 507  SMAPIFVEKLRPKHTPDGST-----VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
              +P    K +   +P+        +  + +++   +  +  F    +++ + + + + D
Sbjct: 1862 KKSPPGSPKKKKSKSPEAEKPPAPKLTRDLKLQTVNKTDLAHFE--VVVEHATECKWFLD 1919

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
               + T     V  +D   F C + +   F S T  ++     +  GS  T         
Sbjct: 1920 GKEITTAQGVTVSKDDQFEFRC-SIDTTMFGSGTVSVVAS---NAAGSVETKTELKVLET 1975

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                    E   P F+ K +   V +G  + ++  ++A+  P   W   G  ++ D    
Sbjct: 1976 PK------ETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNG 2026

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            V I+++ +   S L I N +    G  TV A N  G +     L +       P V++  
Sbjct: 2027 VTIKNEENK--SSLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGP 2081

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
            KS+ +++ E+    A + G P PT+ W  N K V+   T +   T  +  LK    K E 
Sbjct: 2082 KSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQ 2141

Query: 802  VYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-R 858
              T+K  A+NS G     A + V    E N + P F ++  +    E   ++    +   
Sbjct: 2142 TGTVKVTAQNSAGQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGP 2197

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
            +P   ++W  N + ++ S+T+     G+    + I     E+ SG     A N+AG+   
Sbjct: 2198 SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECET 2256

Query: 918  GARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHRE 974
             A+VT++   +K  FV+  Q    T E         T   + +  WY N K++   +  +
Sbjct: 2257 SAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVK 2316

Query: 975  I--IQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDF 1026
            +  + E                G I+        K Q T+ + V K+T +P+F   + D 
Sbjct: 2317 VKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDR 2376

Query: 1027 EVKE-KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
            +VKE +DV             V W  +GE +    N    +K G    + I   +    G
Sbjct: 2377 QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAG 2435

Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALV 1137
            E SC        +       V  V   P     L+++ + +G     +  + + K    +
Sbjct: 2436 ELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKI 2495

Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVE 1192
             W KDG EI    H ++   +    KL I    L+D G  +     E G ++C+A L V 
Sbjct: 2496 TWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVV 2555

Query: 1193 E--PSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248
            +  P     F   +    L   +T     +   D T  V WY    ++  TE   + +  
Sbjct: 2556 KGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNAN 2615

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDV 1305
               T+ I   T D   +  CV  +       +  +    P  V++E    +   + G  +
Sbjct: 2616 GVYTMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTL 2675

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
             L       P+P   W VN K +++ ++ K   +  + ++TIK +    +G       N 
Sbjct: 2676 KLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINE 2735

Query: 1366 CGHADVEMNVTILDKPSPP 1384
             G A  E  + +L +  PP
Sbjct: 2736 YGKATSEATLLVLPRGEPP 2754



 Score =  133 bits (321), Expect = 6e-29
 Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%)

Query: 936  KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989
            K  + ++G + + EC    T  V  KW  + KEI  +    +      EG          
Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953

Query: 990  XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036
                D G   CIV     KD   +T+ V++       +  PEFI  LQD   K  +  +L
Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013

Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
            E ++  E    V W  D + I   +     E    + ++ I ++ +  +G+Y+CI  +  
Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071

Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143
             T++    +TV    P     LQN++++ G K      + KG         +     K  
Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130

Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195
            ++I  S+ I +  D      ++ I     +D   Y     NS  TA  T      VE P 
Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253
                L+      V    +  + V++     DV W+K  K V ED   +     +    TL
Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309
            ++++    D  +YT    +   T +   + EV +    P  V       +K     TL V
Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307

Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367
              +  P P+ EW+ + + ++    H    ++ S S S+TIK     D+G Y  R  N  G
Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367

Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
             A  E N  ++    PP    K + LE+          +   T   +     VE+ + DT
Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422

Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
               I   ++ + QT++   +L  N + +     Y+    + +  + TT  + +I+++   
Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534
             P   + L+ +     E ++L     G P P V W++D K +        AK        
Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 3540

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593
                         Y C A N+ GE +T+  + +Q++    +  + +K  + + G    + 
Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651
              +EG P PEV W+K+G  +  D ++ I  K +  +  + IK+   +   KYT +A+N A
Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660

Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686
            G       LK+    ++K +  E   +  E  +E+  +E
Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699



 Score =  131 bits (316), Expect = 2e-28
 Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%)

Query: 656  RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
            ++   P PDI W     ++  DE  +   + D       + I  V+    G YT +A N 
Sbjct: 570  KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626

Query: 716  EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
             G+AS     ++   EKE  PP  +  L+    ++G+ +    +V G P P + W  +++
Sbjct: 627  YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686

Query: 774  PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            P++       + DG T  + I +  +  D GVYT+K +N  G  E+ A + V+   ++N 
Sbjct: 687  PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
              P F    + +   E   ++  + +T +P P I W+ N + +S SE +    +     L
Sbjct: 746  VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948
             I +V    D G   C  SN  G +S   R+ + V     TF K L+     +E  TV+ 
Sbjct: 806  TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863

Query: 949  ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
            E   S       T     K+  +G +  EI+  +G               G I    +++
Sbjct: 864  EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923

Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
                E+   L V++      + P F++ ++D  VK  + A+ E  +  +   +V W  +G
Sbjct: 924  HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104
              +         E   H  KL I   S    G   C     + R E+    V +     +
Sbjct: 984  HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
             PP+ +  L ++     N   FE+ +  +    V W+  G E++ S+ +++       K+
Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101

Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
             I +  ++DAGE      NS    +  A LTV++         PEF L P +    LTVE
Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152

Query: 1220 IPDETL 1225
               E +
Sbjct: 1153 KGSEAV 1158



 Score =  130 bits (313), Expect = 5e-28
 Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%)

Query: 500  KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            K   +++   P F + L       G +   +C V G P P+I W+R   +++      + 
Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
               D   +L + E    D G + C A+NA G A +     V+  L               
Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582

Query: 620  XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
                    + EG PP F  +     V  G+ I LEC++  +P P + W   G  ++ D  
Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640

Query: 680  ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732
               + E+   +Y   L+I N     EGTY  VA N  G A+    +++  G         
Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789
            +PP+    +  +   +G+ + L  +V  +P P + W K+     A+ T SD    S+   
Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754

Query: 790  ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832
               T+L P  V  D+G+Y + A N  G A+     TV++ P +  A            + 
Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890
            P  +   + I + EK + +L  + + +P P+I W+++ E + P     + ++ DG   EL
Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            V+ +   + D+G Y+CVA N+ G +     V +
Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905



 Score =  127 bits (306), Expect = 4e-27
 Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            + + AP  +E L     P+  + +  C+  G P+P I WF+    + P    Q+    D 
Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
            V  LV+     +DAG + CVA+N  G  S+ T   V     D                  
Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
             + I EG  P F+     +    G  +  EC     P P I WL  G E+  DE I +  
Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731
             +D       L +++V    EG +  VA N  G AS    L I+              GE
Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032

Query: 732  KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782
             E   P++   L +M + +G  V +     G P PT+ W K+ + +       K +    
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092

Query: 783  DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834
            +   H + I+      DEG Y+L+A N  G A+T   + +  P    +A+       PP 
Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893
            F+ + +   V           V  +P P + W+ N + I P   I  Q+  G +  L+I 
Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +   E D+G+Y   A NS G +S  A + + V  +  +K
Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249



 Score =  121 bits (292), Expect = 2e-25
 Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%)

Query: 469  VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
            +P+  L D   YT        E I++    +     E    P  V  L     P+G    
Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891

Query: 529  FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
            F+ +V   P  Q+ W++    IKP+   +          L I     +D   +  V  NA
Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950

Query: 589  AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
            AG   S+  L V  P                        I++G+     ++P+       
Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
              + L+ ++  IP+  I W   G+E+ PD +     E         L I + KK   G Y
Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             VV  N +GE     V+ +K+ +   P      + PLK   V +G+ + L   + G P P
Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100

Query: 765  TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
             + W K+   ++      +    DG T ++ I   KK  D G Y + A+N  G A +   
Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 5158

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            +TV E  E+ ++P  F+   +          +   +V   P P++ W+ N   I   + I
Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 5217

Query: 880  T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928
            T  +    N  L I +V  E D G  KC+A N  G           + H      D+   
Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276

Query: 929  TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985
                          G  + +EC    + T   +W+ + K+I    H EI           
Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336

Query: 986  XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030
                   D+GV  C+  ++    ET     V           +E  P+    L+D  V  
Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396

Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
                 L  ++++   A VVW +DG  ++   +    +E+ G    L I +++  D G Y 
Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455

Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
            C+        + SC+  V V +         P     L +   ++G+  T +  +T GD 
Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514

Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
               ++W+++G  ++      I+ + DG    L + +  + D G Y CE     G +K  A
Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573

Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233
               V       E+P ++   + P+FIL  ++    L   I  E          V W K  
Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632

Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283
              + +  +F   ++  K    L I+  T  D+  Y CV    +  +TTK  V +      
Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692

Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
                   PP+      + R   G  + L     A P P   W  +  I+      + S+ 
Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752

Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
                A+L I      D GIY++   N  G A  +   T+   P   G
Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799



 Score =  116 bits (278), Expect = 9e-24
 Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            EKP  +E    P F+ +L       G+ +  EC+V G P P + W +    +     F+ 
Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643

Query: 559  YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
              +    V  L I+     D GT+ CVA N  G  S+TT+  V     D G    V    
Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698

Query: 618  XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
                           PP F+ K       EG  + LEC++ A P P++ W   G  + P 
Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
            + I +++  D     + L I +     +G Y V+A N  G A       +K     +G +
Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801

Query: 733  -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778
                       + P+++EPL+++ + + +S  L  +  G+P+PTI W K+ +   P   L
Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861

Query: 779  PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829
                  D     ++     +D G Y   AEN+ G A TS  + V     +P +       
Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             + P F         K   ++        NP PSI W ++   +   E I      +  +
Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944
             +I +  + +  G ++CVA+N  G +S  A + I+ ++    + L + + E EE K
Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037



 Score =  114 bits (274), Expect = 3e-23
 Identities = 135/593 (22%), Positives = 242/593 (40%), Gaps = 45/593 (7%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            P++   L+ Q VNK + A FE+ +       +WF DG EI  +  + ++ D + +    +
Sbjct: 1885 PKLTRDLKLQTVNKTDLAHFEVVVEHATEC-KWFLDGKEITTAQGVTVSKDDQFE----F 1939

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ET- 1224
             C +D     S  V      A  +VE  +    L  P+    P  TD    +E+   +T 
Sbjct: 1940 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTV 1999

Query: 1225 -LDVT--------WYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQC--EYTCVLLD 1272
             +DV         WY+  +++ED +   T+ ++  K +LII    +  +   E +  +  
Sbjct: 2000 QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGS 2059

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            ++S+ +L V      P +VD  +   IK             FP P  +W +N KI+++ +
Sbjct: 2060 SESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESR 2119

Query: 1333 H--TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
               T  + D  +  ++  K+E T  G  K+  +N+ G    + ++ +      P   + L
Sbjct: 2120 TITTIKTEDVYTLKISNAKIEQT--GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQL 2177

Query: 1391 --EIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKT 1445
              ++      + W+ E +     T + +++  Q +  ++ + V +        +I   K 
Sbjct: 2178 TDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKP 2237

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
              S    A A N      A E     KV      + P   +  +N  T   E ++ + I 
Sbjct: 2238 EMSGTLTAKAKNA-----AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIV 2292

Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCI---AFNDHGEV 1559
             G P P VTWY + KKL   +  K  Y +                   I   A N  G+V
Sbjct: 2293 TGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKV 2352

Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            + +  + + +K  +    +N D +Q  K G++   TA +EG P P V W  NG  +    
Sbjct: 2353 QATAQLKVDKKTEVPKFTTNMDDRQV-KEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHP 2411

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDKPS 1667
               +T K+    I I  +    + + + EA+N  G+   +V L   KV D P+
Sbjct: 2412 NITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPT 2464



 Score =  112 bits (269), Expect = 1e-22
 Identities = 206/1012 (20%), Positives = 379/1012 (37%), Gaps = 71/1012 (7%)

Query: 726  KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782
            K    EK P P++   LK   V + +  +   +VV        W  + K +      T S
Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932

Query: 783  DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
              D           +   G  ++ A N+ G  ET   + V E  +E  +P  F ++ +++
Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901
             V +  T+++      +P+    WY+N  ++   +  +T   +     L+I N     DS
Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958
            G     ASN  G S   A++T++    T  V    KS   +E +T   +   S     + 
Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014
            KW  N+K +        I+                 G +K   ++   Q++    L V+ 
Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166

Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070
             +  P+F  +L D    E +     +E++  S   +V W  +G+ +         +    
Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226

Query: 1071 IRKLYIRNTSVHDEGEYSCILRDES--C--TAEVTVV--ELPPEIITRLQNQKVNKGNKA 1124
               + I        G  +   ++ +  C  +A+VTV      PE +   QN +       
Sbjct: 2227 TYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESV 2286

Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180
             F   +T K    V W+ +  ++  S  +++    +  K  ++I    ++  G    E  
Sbjct: 2287 KFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346

Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234
               G  + TA L V++ +    FT  + +   V    D   T  +       V W     
Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
             +      T+     + T+ I   T +      CE T  +   K   +L V+ V   P  
Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347
                 +  I  G ++TL+        P+P   W+ +   I    H K    +  S  L+I
Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406
             + +  D G   ++ E+  G A+   ++ ++ K  P  KP   + D + IN+   +    
Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582

Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
                TG+ T  + + +  Q +  TE   + N     T  I  +  + + + +  A N+  
Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
              + S T    KV+    ++    E  L + T    + ++L  +  G P+P V+WY +GK
Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576
            KL+ ++    +                Y     C A N++G+  +   + +  +      
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756

Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
             E +   + + G + +   V  G P P + WY N  ++ N   Y I T +KTS + I   
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816

Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684
                H  +   +A N AG  S    +  Y  D  S+ E      E   + +T
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868



 Score =  111 bits (268), Expect = 2e-22
 Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%)

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
            Q  S  +  +V G P P ITW K++  +   +     SD D      + P +V D G YT
Sbjct: 561  QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A N  G A TSA   V +  E+ A PP F+ + ++   KE   I     V   P P +
Sbjct: 621  CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
             W  +++ + PS      +DG+  +L I +   + D+G Y     N  G     A + + 
Sbjct: 680  VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738

Query: 924  -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
             D +K       Q + E    +EG+ V  +   +   + +  W+ N K +S  +  + I 
Sbjct: 739  ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031
            E                G++ C   ++  S        + V    P F + L+D  V+EK
Sbjct: 799  EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858

Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088
               + EV+++      + +   G+ +K  +   +        ++ I NTS+  HD GE  
Sbjct: 859  STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917

Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137
               ++E  TAE    +TV +        P  +  +++Q V  G  A FE  +    +  V
Sbjct: 918  AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977

Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
             WF +G ++ Q S  +++       KL I       AG   C     VG  +  A L V 
Sbjct: 978  TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035

Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
             P      + P+F+ +  +     D  +  E+  E      VTWY K   ++ +++  + 
Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301
                   + I+    +D  E   V  +++ +     KL V+   F P+         +++
Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            GS+          P P  EW VN + ++
Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181



 Score =  108 bits (260), Expect = 1e-21
 Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E  PP F  K + +   EG  I  EC +   PEP++ WL   + + P  +  +  +    
Sbjct: 644  EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746
               + L+I + +    G YTV   N  G       L ++    +    P+    ++ +  
Sbjct: 702  --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804
             +GE V   + + G+P P I W  N KP+             I IL  K V    +G+ T
Sbjct: 760  DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             +  N  G A     + V  P      PP F    ++ TV+EK T+     V+  P P++
Sbjct: 820  CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875

Query: 865  TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            T+    + +   E   +    +    + I N   +   G+    A N  G +   AR+T+
Sbjct: 876  TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935

Query: 924  DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976
            + E+       TF+K ++ ++ +T E        + +      W+ N  ++       + 
Sbjct: 936  EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027
             E                G + C  ++     ET   LVV     ++  P+F+  L D  
Sbjct: 995  IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054

Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
                +  + EV +  E    V W   GE +K        E  G I K+ I+N  + D GE
Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113

Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126
               +  +    +   A++TV + P  PE   R  +  V KG++A F
Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159



 Score =  102 bits (244), Expect = 1e-19
 Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%)

Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144
            +  DES   E+     P   P+ IT++++ K  KG+ A FE  +  TKG    +W KDG 
Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925

Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194
            EI+    I++ T  G +    Q+L + +   +DAG+Y+C V    G   C A LTV E  
Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985

Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246
                  + PEFI+        T   + +E   I +    V+W +  K++ +++     + 
Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304
             V++ T+   + +   Q +YTC+  + + T+K +  + V    P      +   +  G  
Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356
            + L    +  PQP+ ++   S+  K + K T  S   I+    +    + I ++   D  
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             YK    N+ G A     +T   + +P  +  + +           E +  G++  + + 
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222

Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             + + +       +K   +T      ++   T  + ++ A A N    +++S   E  + 
Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527
                 ++ PT  + L     + NE   L+    GVP P V W +DG+ ++T      AK 
Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586
                                Y C A N  GE +T     + +  V     E +   + K 
Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644
             +   ++  + G P P V W+K+   +  D  + I   T   +  + I + ++     Y+
Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688
              A N AG +       +      PE    +R +  RE  T++ K
Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502



 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F + L  K   + STV FE  V G+P P +T+      +K  ++       D    + 
Sbjct: 844  PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903

Query: 570  IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            I      +  G     A+N  G A S   L VE    +  S                   
Sbjct: 904  IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                 PTF K  + Q V  G   + E  +   P P++ W   G ++  D+  S  ++ + 
Sbjct: 946  -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            H +   L I + +    GT    A N  G  E    +V+     +K+PP+ +E L     
Sbjct: 998  HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804
                +V+   +V G P+PT+TW    + +K        +   SI I +K  K++D G   
Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A NSEG  ET A +TV++        P F  R   +TV++       A     P+P+ 
Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171

Query: 865  TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917
             W  N   +   +    +T++    DG +I  + T    SE++      VA N+ G    
Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
            GA++TI+ +K + V   Q    +E  K +  + + +   +T
Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%)

Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
            D+ W +D  ++ + +++ +  ++ G    + I    V D G Y+C+  +E    S +A  
Sbjct: 578  DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636

Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154
             V+++     PP  +T+L++++  +G+   FE E+    +  + W  D   ++ S+  +L
Sbjct: 637  RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209
              DG+  KL+I D   DD G Y+ ++    G+ +  A L V+ +P  N     PEF    
Sbjct: 697  QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754

Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
               +        + +V   D   ++ W+     + ++EK   IS+     L I+  T   
Sbjct: 755  EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814

Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
                TC     L  A    +LKV V   PP       +  ++  S V   VD   +P+P 
Sbjct: 815  DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
              + +  K +K  +     +        S+    ++  D  I   + +N  G A+    +
Sbjct: 875  LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933

Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433
            T+  ++      P  L+     I    D+   TG   +    V         W I+   +
Sbjct: 934  TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489
             +    ++    N  ++    +       +  A      ++      + +P  +K P K 
Sbjct: 987  DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046

Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540
              I  +  E ++ T +F     G P+P VTWY  G++LK +       ++          
Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    + +A N  G  ET   + +Q+KP         +    + G E + +A   GI
Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651
            P P   W  NG K+ + +E    T+++++V     L    ++ Y        ++ A NT 
Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
            G       L +  +P K    V  +++S   V  E    + +   E T
Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            G  PTF+K  + + + EG   L++ +L +  P+P I WL  G EI  D +  +  E D  
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748
            +  S+L+    K   +G  T+ A +  G A     L +  G     P     +  + + +
Sbjct: 2520 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 2576

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806
            G+++     + G+P P + W    + V A       + + +  +K   V  +    +K  
Sbjct: 2577 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 2636

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A N  G   T   + V  P      P  F     + T +E  T+KL A +   P P ++W
Sbjct: 2637 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2691

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924
            Y N + +  S+ I  + +     + I ++  +  SG   C A N  GK++  A + +   
Sbjct: 2692 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2750

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980
             E   F++ L         K V     T     S  WY N KEI   D   I+ + +
Sbjct: 2751 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2807



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 20/271 (7%)

Query: 653  LECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            LEC+L+    P P + W    + +   E+  ++  + ++     +KI  V     G    
Sbjct: 2580 LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVY----TMKIHGVTADMTGKIKC 2635

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            VA N+ GE S    LK+      P +    L     R+G+++ L A ++G P P ++W  
Sbjct: 2636 VAYNKAGEVSTEGPLKVVA--PIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693

Query: 771  NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            N K ++    +   S+  T+++TI K       G    +A N  G A + A + V     
Sbjct: 2694 NGKKLEESQNIKIHSEKGTYTVTI-KDITCDYSGQVVCEAINEYGKATSEATLLVLP--- 2749

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDG 885
               EPP F+     +  +  GT K+V +V  T +P PS+TWY NN+ I  S+  T   D 
Sbjct: 2750 -RGEPPDFLEWLSNVRART-GT-KVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDD 2806

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            +   L I + + ++  G+  C A N AG+ S
Sbjct: 2807 KTSTLTINSFNPDVHVGEIICKAENDAGEVS 2837



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+ KL+D E KE DV   E E+      ++VW  D + ++P  + +  +  G   KL 
Sbjct: 648  PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125
            IR+    D G Y+  +++E       AE+ V   P      PE    ++  + ++G +  
Sbjct: 707  IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766

Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
            F+  +T GD    + WF +G  +  S  ++   +     L I D      G  +C+    
Sbjct: 767  FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825

Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235
            +G++ C   L V  P    T   P E   V   +     V++   P+ TL  T   K+  
Sbjct: 826  LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286
              +     +  D   R  I     +    E      +    A+S  +L VE  E      
Sbjct: 886  NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345
            P  + D E +  +K G         +  P P   W +N  K+ +     K    +    L
Sbjct: 946  PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400
            TI   +   AG    R EN  G  + +  + +L        P  +EI     ++    + 
Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062

Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
            ++   E     T+ +Y+ + +E+  ++ + ++    + + SI+N+K   +   RA A N 
Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
               S+ S+ T+  K+  + K  +P  +    ++T E   +   +    G+P P   W  +
Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176

Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566
            G+K++     A+ T +                 Y          +A N  G  ET   + 
Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236

Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
            I+ +K  + +  +D+    +V  E  +   ++   P           L + K   ++T E
Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293

Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
             TS +     E K S S S  T+    + G +   +++   +  SK +    +RE
Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%)

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
            +Y  E   + +   +   P+PDI W F+G +I      S           + L IT   K
Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
               G Y   A N  G+A   I++ + T     P  I+PL +      + + +  +V G P
Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534

Query: 763  RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
             P + W K  +P+     +    DG      I+     +D G+Y+  A N  G A TS  
Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594

Query: 820  ITVEEPTEEN 829
            +TVE   + N
Sbjct: 6595 VTVEAEGDYN 6604



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%)

Query: 486  KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
            +++   I+K+       +++ + APIF  +LR  +        FEC V   P P++TW  
Sbjct: 7504 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 7563

Query: 546  QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
            Q  I++ S D      D+NVA L++    P D G + C A N  G   S+  LI
Sbjct: 7564 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 7616



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531
            K+++ ++P     L++ TT+ +E + L C   G P+PKV+W  D K +     T E+   
Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589
                            Y CIA N  G  +T   + +Q + PV T   ++++ K   +G++
Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103

Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641
             +++  ++G P P V +Y      K   K+ +     I   +  +  R  I ++ +    
Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163

Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             Y   A+N+ G  TS+ ++T KV + P   +G        +E + +E K       +E  
Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
            K      E  N+   K  + +  V T  +++        +   A NP G +E+
Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E+Q   P FVE L  K     +TV FE +VEG P+P +TW+ +   +K S   ++   D 
Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622
            ++  + I+ +  EDAG    VA N+ G   +  +L V+  P +       V         
Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156

Query: 623  XXXADILEGIP-PTFSKKPKAQYVDEGSD 650
               +    GIP PT+      + V +G +
Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565
            S+ P F +KLRP    +  T+  +  V G P P + WF+    I          D+    
Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 3538

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608
             TL I++   ED G +TC A N AG A +T  + V    EAPL   G
Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%)

Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G P P +TWY+D  +L      T  +  +                 Y C+A N++G+  T
Sbjct: 573  GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632

Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            S    V+ ++++         ++ K  K GD       +EG P PE++W  +   L    
Sbjct: 633  SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            ++ +    +T+ + I++ +   +  YT++  N  G+   +  L V   P K
Sbjct: 693  DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
            ++P + +PL+NI     +   L C F G P+P + W++DG+++          + +    
Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581
                         Y+C+A N +G   TSC V +    +KP  I  S  + K         
Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932

Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639
             ++ K GD      +  G P P + W K+G +L +D++  +    + T  + + ++    
Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992

Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
               +   A+N  GT+S +  L +
Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           D   YT  +Q +      K  +F +   ++  +AP F   +      +G  V+F+  + G
Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
            P P+I WF     +  S+  + +  +D +  L I++V     G  TC   N  G AS  
Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832

Query: 596 TELIVEAP 603
             L V  P
Sbjct: 833 GRLKVRVP 840



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534
            ++P    PL     +P + +   C+  G P P + W +DG +L +      +A  +    
Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586
                         ++C+A N+HG   T           +G +  P +    E+ K + + 
Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042

Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633
            G       E  V  +I    GIP P V WYK+G ++  D    K    T +     + I 
Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
                    +Y++EA+N  G++  E +L +
Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%)

Query: 748  QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
            + +++ +   V G P P I W         + P       + G + +   +     ++ G
Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             Y   A+N  G A+ +  I V+  T  N   PL +N+    T      +++  RV   P 
Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            P + W +    I  S  I    DG  +  +I N     DSG Y CVA N AG+++    V
Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595

Query: 922  TIDVE 926
            T++ E
Sbjct: 6596 TVEAE 6600



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 26/93 (27%), Positives = 49/93 (52%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F++ L  K       ++ + +V+G P P++ W ++   I  S   +   D   + +L+
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            I +    D+G ++CVA N AG A+++  + VEA
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559
            Q  AP+F ++L+ K    G  +   C V+G P+P + +  F +T  ++     S    + 
Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142

Query: 560  YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612
            +D  N    +VI ++  ED  ++  +A N+ G A+ST+++   VEAP+ + G + T
Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            L V E    + +  AP F+  L+ K T     V  EC+V G P+P+++W      I  +Q
Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604
            +       + V  + I        G +TC+A+N  G + +   L V  EAP+
Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 23/71 (32%), Positives = 36/71 (50%)

Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           S+ +   +V GYP P ITW++    +   +    Y D+D    + I  V   D G +TC+
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622

Query: 585 AKNAAGFASST 595
           A N  G AS++
Sbjct: 623 ATNEYGQASTS 633



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%)

Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
            ET    KV++  K  + P     L+++     + +++  I   +  P   WY++G  L+ 
Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022

Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578
             K   T +N                   + A N+ G  E+S  + +      P++    +
Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
             +  K     E+  T  I G P P V W  N   +E  +       E    ++I   K  
Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIE 2140

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692
             +    + A N+AG  S +  LKV      P+    +  +++ E   + W   LD
Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%)

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846
            L+PK  +       KA ++  I    A I    P  T++N +    P+F  R +++ +++
Sbjct: 7482 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 7541

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
                     V+ +P P +TW    +I+  ++ +T   D  N+  +I N  +  D G+Y C
Sbjct: 7542 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 7600

Query: 907  VASNSAGKSSHGARV 921
             A N  G      R+
Sbjct: 7601 TAINEYGTDKSSCRL 7615



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            +   P P+V W   G  LE++    I      + + +         +Y   A N  GT  
Sbjct: 7551 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 7610

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711
                L   + PS+P  P    E+S ++ + I+W+ P     LE   Y +E      N   
Sbjct: 7611 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 7668

Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
              WI V++   D E+  ++ L+    Y FRV AQN  G      S  IV
Sbjct: 7669 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 7716



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068
            +E  P   R L +  + E +V  + V      T  V W +DG+ I    P   +  F   
Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110
              I  L I N S  DEGEYS    ++  +A+    + ++                PP  +
Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153

Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168
             +L+N+ V       F+  +    A  V WF +G +I     I++ +  G    L I D 
Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213

Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
             L+DAGEY        G++  +A+L V  P ++      E  + P  T+ Y
Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%)

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            F P      R+  +++           A P P   W    KI++         D+  A L
Sbjct: 7526 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 7585

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
             +      D G Y     N  G       +   + PS PG+P       + I I W+ PE
Sbjct: 7586 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 7645

Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
                   I Y +EY+     +    WI+V + I      +++L     Y+FR  A N
Sbjct: 7646 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 7702



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437
            P+PP + P I E+    + + W   +        + YV+E +E+   +W  ++ NI +  
Sbjct: 6275 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 6334

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              ++NL+   SY+FR  A N   ISD S
Sbjct: 6335 CKVRNLELGKSYQFRVRAENIYGISDPS 6362



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+ + +  Y+ +    + EC + A P P + W F+G+  + + N  V IE D ++  +
Sbjct: 7528 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 7583

Query: 694  VLKITNVKKFQEGTYTVVAVNREG 717
             L + +   +  G Y   A+N  G
Sbjct: 7584 RLILNHAAPYDLGEYVCTAINEYG 7607



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%)

Query: 503  SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558
            SE+ + AP F   +  K +  +  T+     V G+P P I W FR   I    P+   ++
Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
            Y    +  TL I     E+ G + C AKN  G A
Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472
           E R      A+  Y  + +  EAI L +G+ + +LD  N   W V+ K      GWVP  
Sbjct: 61  ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120

Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500
           Y      +  Y Q++   +I+ + + ++
Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P++ WYK+  +L  D+ +   + E     + I  ++ + + +YT  A+N  G +
Sbjct: 571  VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
            S     +V     +   P  + ++
Sbjct: 631  STSAFFRVLKVEKEAAPPAFVTKL 654


>UniRef50_UPI0000E460FC Cluster: PREDICTED: similar to Bent, partial;
            n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to Bent, partial - Strongylocentrotus purpuratus
          Length = 1581

 Score =  256 bits (626), Expect = 6e-66
 Identities = 186/740 (25%), Positives = 312/740 (42%), Gaps = 39/740 (5%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            D  R+ +IK G +  L V ++A P P   W +N   +    H     + +   + +K  +
Sbjct: 244  DKLRDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMAD 303

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNS 1410
             +D G Y+L+L N+ G      NV + D+PSPP  P  I ++ +   ++ W  PE+ G S
Sbjct: 304  KSDTGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSLAWQAPEDDGGS 363

Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             I+ Y++E  E D   W  V    +    +   L   ++Y+FR  A N    +     +E
Sbjct: 364  DILNYIIEKSEGDDDYWSKVTGFCQDPKGVATKLNQGTNYKFRVRAENSAGFTSEPLESE 423

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTA 1525
              K  K     + +  KP      +   D+E T         K++ Y    R+ +  +  
Sbjct: 424  MVKA-KNPYEAASSPGKPSIPTYDKTTADLEWTA-SSSDGGDKISGYIVERRESRSSRWV 481

Query: 1526 KATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG------EVETSCVVGIQQKPVITISN 1577
            KAT E                 Y  +  A N  G      E +        + P I  S 
Sbjct: 482  KATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSG 541

Query: 1578 EDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
              +   + K G  + +     G P P V W K+  +++    + + T E  S +     +
Sbjct: 542  FGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAE 601

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            R     Y I+  N+ G+ S  + + V D+P+ P GP+   E ++ESV + WK P  DG  
Sbjct: 602  RGDQGSYMIKLDNSRGSDSYSLNVLVLDRPTAPGGPIEYSEFTKESVRLTWKAPEQDGNS 661

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALES 1755
             ++ Y++E+ +P  + W +V        T C+ K L    +Y+FR+ A N  G SE LE 
Sbjct: 662  SVSGYSVERRDPKKDFWTRV--TSNAPTTSCVVKDLVYQNDYVFRICAINQYGTSEPLEG 719

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWK 1814
              + +K   D P           +   S  ++W P + +GGSP+  Y VE    + ++W+
Sbjct: 720  RQVKVKLPFDEPD-APSAPKIDAMSRISADLSWAPPDHDGGSPVTGYLVEFHPTDAREWQ 778

Query: 1815 XXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                         +  L   T YQFR+ A N+ G   P  S + +     + P   P   
Sbjct: 779  RANSFPIRDTVYTVPNLREGTEYQFRVIAANDAGEGKPSRSSESVVAKDPILPADAPGRP 838

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSVHEHCIE 1928
             + + T  S  + W++P S+GG+PI  Y IE +      KG  WT  + V        + 
Sbjct: 839  TLEKVTKDSAAISWSKPVSDGGAPIKGYTIEKRKAGPGPKG-DWTPCLEVSPKEESAVVP 897

Query: 1929 NIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLE-IRMVGS-----N 1981
            ++ E +E+ FR+ A N      P+  + +  +E     P      LE I++ G      N
Sbjct: 898  DLVEGEELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEIN 957

Query: 1982 IVMTSWGTP--EWD-GGAPL 1998
            + +T + TP   W+ G +P+
Sbjct: 958  LPLTGFPTPTATWELGSSPV 977



 Score =  238 bits (583), Expect = 1e-60
 Identities = 169/639 (26%), Positives = 274/639 (42%), Gaps = 25/639 (3%)

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            + ++K G    + +    FP P   W + S  +K+      +       L +   E  DA
Sbjct: 945  DIKVKGGEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDA 1004

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            G Y + ++N+ G     + VT++ +P  P G   + +I  +S+ + W +P N G   +  
Sbjct: 1005 GRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVTLSWKQPVN-GPEDVEN 1063

Query: 1415 YVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            YVVE ++ DT  W  V + +      ++NLK    Y+FR  A N+  +S    T+E   +
Sbjct: 1064 YVVEKRDPDTGAWSKVSSFVPSPHFKVKNLKEGGEYQFRVSAENQYGVSKPI-TSE--TI 1120

Query: 1474 IKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKAT 1528
            I +     P +  +P    TT     I+ T        P V +  + +K      TA   
Sbjct: 1121 IAKNPFDPPGMPSQPEVTTTTSTTISIQWTRPSNDGGNPIVGYTVEKRKEHGDWSTATRA 1180

Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VETSCVVGIQQKPV---ITISNEDIKQ 1582
                               ++  A N+ G     ++S  +  +  PV   +  S+ + + 
Sbjct: 1181 PVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPSDSSDAITARPPPVKPKVDSSSRNREV 1240

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWY---KNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                G+++ V    EG PPP + W    KNG  +E          E +S++   E +R  
Sbjct: 1241 TAVAGEKFRVEISFEGSPPPNITWSRSDKNGITVEPSNRIAFEDTELSSIMANSEAERGD 1300

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
            +  Y +  SN  GT +  V + V DKPS PEGP+   +++ +   + WKPP DDGG  +T
Sbjct: 1301 AGTYAVTFSNEKGTDTATVRIIVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVT 1360

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758
             Y IEK     + W KV+   R   TY +  L+E     FRV A+N  G    LE S+ I
Sbjct: 1361 NYVIEKQAAGRSAWTKVSTYVR-TTTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAI 1419

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW--KXX 1816
             IK   D P           +D   V ++W   E +GGSPII Y VE ++   +W     
Sbjct: 1420 TIKDPFDAPE-APGKPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERDGEWIPVND 1478

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     +  L     Y+FR++A+N+ G      +   I     +  PS P   V S+
Sbjct: 1479 YNVKETTLPVGNLRDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPSAPGVPVASD 1538

Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
                +V L+W +P S+GGS +  Y++E +      W  +
Sbjct: 1539 IGRDTVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPV 1577



 Score =  226 bits (553), Expect = 5e-57
 Identities = 184/740 (24%), Positives = 313/740 (42%), Gaps = 32/740 (4%)

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412
            D+G Y + ++N  G       VT++DK S P  P  I +I S  + + W+ PE+ G   +
Sbjct: 10   DSGGYTVTVQNAHGTETATAQVTVIDKSSAPKAPLEITDIFSEYLTLTWNAPEDDGGLPL 69

Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
              Y+VE +++  + W  + + TK  T  +  L   + Y FR  A N   +S   E ++  
Sbjct: 70   SNYIVERRDVRRSGWSVINDTTKDTTMKVTRLVEGTEYMFRVAAENSEGVSKWLEASK-- 127

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVP-QPKVTWYRDGKKLKTAK 1526
             V+ +     P     +  +     + +EL        GG P +  V   R+    +  +
Sbjct: 128  SVVAKNPYDEPG-SPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQE 186

Query: 1527 ATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVI---TISNEDI 1580
             T                     ++  A N  G  + S C    + KP     T+  + +
Sbjct: 187  VTTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECSAPQKTKPKFARPTLKGDKL 246

Query: 1581 KQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            +  K K G E++++ + E  P PE+ W  NGNK+       +  +E+ + +++K   +S 
Sbjct: 247  RDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKSD 306

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
            +  Y ++ +N +G       + V D+PS P GP+ + ++  +  ++ W+ P DDGG ++ 
Sbjct: 307  TGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSLAWQAPEDDGGSDIL 366

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF-SEALESEPI 1758
             Y IEK E D++ W KV    +D +     KLN+   Y FRV A+N  GF SE LESE +
Sbjct: 367  NYIIEKSEGDDDYWSKVTGFCQDPKGVA-TKLNQGTNYKFRVRAENSAGFTSEPLESEMV 425

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXX 1816
              K   +  S           D  +  + W  S  +GG  I  Y VE ++    +W K  
Sbjct: 426  KAKNPYEAAS-SPGKPSIPTYDKTTADLEWTASSSDGGDKISGYIVERRESRSSRWVKAT 484

Query: 1817 XXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPPSQPRNFVV 1874
                   A  +  L     Y FR++A N  G S P   SD  +   +   P      F +
Sbjct: 485  REPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSGFGL 544

Query: 1875 SESTSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
             +   ++        P     +P   ++ + K +K      + T   +    C    +  
Sbjct: 545  GDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLC-SFAERG 603

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
            D+  + I  +N+ G    ++S S+ +      P+ P  P+E        V  +W  PE D
Sbjct: 604  DQGSYMIKLDNSRG----SDSYSLNV-LVLDRPTAPGGPIEYSEFTKESVRLTWKAPEQD 658

Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
            G + + GY++  RD  K  W  V   +  T    ++DL   + Y+ RI A N+ G SEPL
Sbjct: 659  GNSSVSGYSVERRDPKKDFWTRVTS-NAPTTSCVVKDLVYQNDYVFRICAINQYGTSEPL 717

Query: 2054 ESDEPFKVIPGEGSHADEEP 2073
            E  +    +P +   A   P
Sbjct: 718  EGRQVKVKLPFDEPDAPSAP 737



 Score =  192 bits (468), Expect = 9e-47
 Identities = 142/518 (27%), Positives = 233/518 (44%), Gaps = 29/518 (5%)

Query: 1569 QKPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
            ++P + I + EDIK K   G+++ +   + G P P   W    + ++      +TT    
Sbjct: 934  ERPKLDIGSLEDIKVKG--GEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTARTY 991

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
            + +++   +R  + +YTI   N +G+ +  V + V  +P  P+GPV + +IS  SVT+ W
Sbjct: 992  TKLKVDSAERQDAGRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVTLSW 1051

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            K P+ +G  ++  Y +EK +PD   W KV+        + ++ L E  EY FRV A+N  
Sbjct: 1052 KQPV-NGPEDVENYVVEKRDPDTGAWSKVSSFVPSPH-FKVKNLKEGGEYQFRVSAENQY 1109

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G S+ + SE I+ K   D P             + ++ I W     +GG+PI+ Y VE +
Sbjct: 1110 GVSKPITSETIIAKNPFDPPGMPSQPEVTTT-TSTTISIQWTRPSNDGGNPIVGYTVEKR 1168

Query: 1808 QEGKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            +E   W                KL+  T+Y+FR+ A NE G   P  S D IT      P
Sbjct: 1169 KEHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPSDSSDAIT---ARPP 1225

Query: 1866 PSQPRNFVVSESTSRSVTL----KWTEPESNGGSPITNYIIEFKTVKG---KSWTKIVTV 1918
            P +P+  V S S +R VT     K+    S  GSP  N         G   +   +I   
Sbjct: 1226 PVKPK--VDSSSRNREVTAVAGEKFRVEISFEGSPPPNITWSRSDKNGITVEPSNRIAFE 1283

Query: 1919 GGSVHEHCIENIKEK-DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
               +      +  E+ D   + ++  N  G    T++ +VR+      PS P  PL    
Sbjct: 1284 DTELSSIMANSEAERGDAGTYAVTFSNEKG----TDTATVRIIV-VDKPSAPEGPLAATD 1338

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
            V ++    SW  P+ DGG+ +  Y I  +   ++ W +V    V T  +++ +L E    
Sbjct: 1339 VTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTY-VRTTTYDVVNLDEGSVL 1397

Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075
              R+ A N+ G+  PLE  +   +   +   A E PG+
Sbjct: 1398 KFRVSAENQHGVGPPLEGSQAITI--KDPFDAPEAPGK 1433



 Score =  168 bits (408), Expect = 2e-39
 Identities = 163/728 (22%), Positives = 291/728 (39%), Gaps = 43/728 (5%)

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSP------PGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R EN+ G     +   ++   +P      PGKP+I   D ++ ++ W    + G   
Sbjct: 405  FRVRAENSAGFTSEPLESEMVKAKNPYEAASSPGKPSIPTYDKTTADLEWTASSSDGGDK 464

Query: 1412 IIYYVVEYQEIDTTEWI-SVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            I  Y+VE +E  ++ W+ + +   KT   ++ NL     Y FR +A N   +S  S  ++
Sbjct: 465  ISGYIVERRESRSSRWVKATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESD 524

Query: 1470 YYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
            ++  + + + ++P ++     L ++  +     ++   F G P P V W +D K++K + 
Sbjct: 525  HH--VAKAQFEAPKIDTSGFGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSD 582

Query: 1527 A----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
                 T E+                Y     N  G    S  V +  +P       +  +
Sbjct: 583  RFTVDTTESNSTLLCSFAERGDQGSYMIKLDNSRGSDSYSLNVLVLDRPTAPGGPIEYSE 642

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHS 1640
              K     L     E      V  Y +  + +  K++   +T+   T+   +K+L   + 
Sbjct: 643  FTKESVR-LTWKAPEQDGNSSVSGY-SVERRDPKKDFWTRVTSNAPTTSCVVKDLVYQND 700

Query: 1641 SKYTIEASNTAGTSSV----EVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
              + I A N  GTS      +V +K+ +D+P  P  P I   +SR S  + W PP  DGG
Sbjct: 701  YVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAPKI-DAMSRISADLSWAPPDHDGG 759

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754
              +T Y +E H  D   W +          Y +  L E  EY FRVIA N  G  + +  
Sbjct: 760  SPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIAANDAGEGKPSRS 819

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--- 1811
            SE +V K  + +P+          +  +S  I+W     +GG+PI  Y +E ++ G    
Sbjct: 820  SESVVAKDPI-LPADAPGRPTLEKVTKDSAAISWSKPVSDGGAPIKGYTIEKRKAGPGPK 878

Query: 1812 -KWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
              W            A +  L      +FR+ A N+     P        I      P  
Sbjct: 879  GDWTPCLEVSPKEESAVVPDLVEGEELEFRVRANNDECPGKPSAPTPATVIEDKPERPKL 938

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
                +           +   P +   +P   + +    VK +S   +VT   +  +  ++
Sbjct: 939  DIGSLEDIKVKGGEKFEINLPLTGFPTPTATWELGSSPVK-ESGRVLVTTARTYTKLKVD 997

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988
            + + +D   + I+ +N  G        +V  E     P  P  P+++  +  N V  SW 
Sbjct: 998  SAERQDAGRYTITVKNDSGSDTARVKVTVIAE-----PDVPQGPVQVSDISPNSVTLSWK 1052

Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             P  +G   +  Y +  RD     W +V    V +  F +++L E   Y  R+ A N+ G
Sbjct: 1053 QPV-NGPEDVENYVVEKRDPDTGAWSKVSSF-VPSPHFKVKNLKEGGEYQFRVSAENQYG 1110

Query: 2049 LSEPLESD 2056
            +S+P+ S+
Sbjct: 1111 VSKPITSE 1118



 Score =  161 bits (392), Expect = 1e-37
 Identities = 130/453 (28%), Positives = 202/453 (44%), Gaps = 28/453 (6%)

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            R+ S  YT+   N  GT +    + V DK S P+ P+ + +I  E +T+ W  P DDGGL
Sbjct: 8    RADSGGYTVTVQNAHGTETATAQVTVIDKSSAPKAPLEITDIFSEYLTLTWNAPEDDGGL 67

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755
             L+ Y +E+ +   + W  + D  +D  T  + +L E  EYMFRV A+N  G S+ LE S
Sbjct: 68   PLSNYIVERRDVRRSGWSVINDTTKDT-TMKVTRLVEGTEYMFRVAAENSEGVSKWLEAS 126

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814
            + +V K   D P            D + V + W   +K+GG+PI  Y VE ++ G  +W+
Sbjct: 127  KSVVAKNPYDEPG-SPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQ 185

Query: 1815 XXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                        ++  L +N   +FR+ A N+ GT  P             T P   R  
Sbjct: 186  EVTTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECS-----APQKTKPKFARPT 240

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIK 1931
            +  +   R + +K       G   + + I E       SWT     V GS H   ++N +
Sbjct: 241  LKGDKL-RDIKIK------AGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVG-LKNEE 292

Query: 1932 EKDEIIFRISAENTVG---VSLPTESQSVRLEKHATV---PSPPTAPLEIRMVGSNIVMT 1985
            E  E+  +++ ++  G   + L  +S  V+   +  V   PSPP  P+EI  V ++    
Sbjct: 293  ELTEVKVKMADKSDTGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSL 352

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
            +W  PE DGG+ +L Y I   +     W +V        K     L++   Y  R+ A N
Sbjct: 353  AWQAPEDDGGSDILNYIIEKSEGDDDYWSKVTGF-CQDPKGVATKLNQGTNYKFRVRAEN 411

Query: 2046 EIGL-SEPLESDEPFKVIPGEGSHADEEPGEQT 2077
              G  SEPLES+      P E + +  +P   T
Sbjct: 412  SAGFTSEPLESEMVKAKNPYEAASSPGKPSIPT 444



 Score =  156 bits (378), Expect = 7e-36
 Identities = 186/791 (23%), Positives = 313/791 (39%), Gaps = 85/791 (10%)

Query: 1302 GSDVT-LLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            GS VT  LV++   P    EW   NS  I+   +T P++  +      + +   DAG  K
Sbjct: 759  GSPVTGYLVEFH--PTDAREWQRANSFPIRDTVYTVPNL-REGTEYQFRVIAANDAGEGK 815

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
                +      V     IL   +P G+P + ++   S  I W +P + G + I  Y +E 
Sbjct: 816  PSRSSE----SVVAKDPILPADAP-GRPTLEKVTKDSAAISWSKPVSDGGAPIKGYTIEK 870

Query: 1420 QEIDTT---EWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            ++       +W     ++  + S  + +L       FR  A N+      S  T     +
Sbjct: 871  RKAGPGPKGDWTPCLEVSPKEESAVVPDLVEGEELEFRVRANNDECPGKPSAPTP--ATV 928

Query: 1475 KETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWY-------RDGKKLKTAK 1526
             E K + P ++   L++I  +  E  E+     G P P  TW          G+ L T  
Sbjct: 929  IEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTA 988

Query: 1527 ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV--GIQQKPV----ITISNED 1579
             TY   +                K  + +D   V+ + +    + Q PV    I+ ++  
Sbjct: 989  RTYTKLKVDSAERQDAGRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVT 1048

Query: 1580 IKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            +  K  V G E +   V+E   P    W K            +++   +   ++K LK  
Sbjct: 1049 LSWKQPVNGPEDVENYVVEKRDPDTGAWSK------------VSSFVPSPHFKVKNLKEG 1096

Query: 1639 HSSKYTIEASNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
               ++ + A N  G     TS   +    +D P  P  P +    S  +++I+W  P +D
Sbjct: 1097 GEYQFRVSAENQYGVSKPITSETIIAKNPFDPPGMPSQPEVTTTTST-TISIQWTRPSND 1155

Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG----- 1748
            GG  +  Y +EK + ++  W           ++   KL E   Y FRV A N  G     
Sbjct: 1156 GGNPIVGYTVEKRK-EHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPS 1214

Query: 1749 -FSEALESEPIVIKTALDVPSXXXXXXXXXX------IDNESV---YITWFPSEKNGGSP 1798
              S+A+ + P  +K  +D  S                I  E      ITW  S+KNG + 
Sbjct: 1215 DSSDAITARPPPVKPKVDSSSRNREVTAVAGEKFRVEISFEGSPPPNITWSRSDKNGITV 1274

Query: 1799 IIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
                ++  +                +  ++    T   + +   NE GT    T+  +I 
Sbjct: 1275 EPSNRIAFED------TELSSIMANSEAERGDAGT---YAVTFSNEKGTD---TATVRII 1322

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
            +    + P  P     ++ T+    L W  P+ +GGS +TNY+IE +     +WTK+ T 
Sbjct: 1323 VVDKPSAPEGP--LAATDVTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTY 1380

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977
              +   + + N+ E   + FR+SAEN  GV  P E SQ++ ++     P  P  P     
Sbjct: 1381 VRTT-TYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAITIKDPFDAPEAPGKP-NADE 1438

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
            V    V  SW  PE DGG+P++GY +  R+     W+ V   +V      + +L +   Y
Sbjct: 1439 VDRGFVRLSWEAPEADGGSPIIGYIVEKRE-RDGEWIPVNDYNVKETTLPVGNLRDTAEY 1497

Query: 2038 MIRIYARNEIG 2048
              R++A+N+ G
Sbjct: 1498 EFRVFAKNKAG 1508



 Score =  136 bits (328), Expect = 8e-30
 Identities = 111/474 (23%), Positives = 210/474 (44%), Gaps = 29/474 (6%)

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNV 1375
            P   +IV  + +++   +  +  +K  ++ + ++      ++++  EN+ G +  +E + 
Sbjct: 68   PLSNYIVERRDVRRSGWSVINDTTKDTTMKVTRLVEGTEYMFRVAAENSEGVSKWLEASK 127

Query: 1376 TIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--I 1428
            +++     D+P  PG P +++ D   + + W +P+  G + I  YVVE +E+ +T W  +
Sbjct: 128  SVVAKNPYDEPGSPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQEV 187

Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KP 1487
            +   +  T+  + NL  N    FR  AVN+      SE +   K   + K   PT++   
Sbjct: 188  TTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECSAPQKT--KPKFARPTLKGDK 245

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXX 1543
            L++I  +  ++  L+ IF   P P+++W  +G K+           E             
Sbjct: 246  LRDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKS 305

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW-LVTAVIEGIPPP 1602
                Y+    ND G+V+TSC V +Q +P  +     I+      D+  L     E     
Sbjct: 306  DTGTYELKLTNDSGDVKTSCNVIVQDRP--SPPRGPIEISDVFADKCSLAWQAPEDDGGS 363

Query: 1603 EVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            +++ Y    K E D +Y   +T   +       +L +  + K+ + A N+AG +S  +  
Sbjct: 364  DILNYII-EKSEGDDDYWSKVTGFCQDPKGVATKLNQGTNYKFRVRAENSAGFTSEPLES 422

Query: 1661 KV------YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            ++      Y+  S P  P I     + +  +EW     DGG +++ Y +E+ E  ++RW+
Sbjct: 423  EMVKAKNPYEAASSPGKPSI-PTYDKTTADLEWTASSSDGGDKISGYIVERRESRSSRWV 481

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767
            K          Y +  L    EY+FRV A+N  G S  + ES+  V K   + P
Sbjct: 482  KATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAP 535



 Score =  116 bits (278), Expect = 9e-24
 Identities = 137/620 (22%), Positives = 232/620 (37%), Gaps = 47/620 (7%)

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
            T   TW    S ++++ +  + +      L +      D   YT  + +     T ++KV
Sbjct: 965  TPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDAGRYTITVKNDSGSDTARVKV 1024

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             V+  P       +   I   S           P+  + ++V  +       +K S    
Sbjct: 1025 TVIAEPDVPQGPVQVSDISPNSVTLSWKQPVNGPEDVENYVVEKRDPDTGAWSKVSSFVP 1084

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSS 1396
            S    +K ++      +++  EN  G +    + TI+     D P  P +P +    S++
Sbjct: 1085 SPHFKVKNLKEGGEYQFRVSAENQYGVSKPITSETIIAKNPFDPPGMPSQPEVTTTTSTT 1144

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAY 1454
            I+I W  P N G + I+ Y VE ++ +  +W +        TS     L   +SY FR  
Sbjct: 1145 ISIQWTRPSNDGGNPIVGYTVEKRK-EHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVK 1203

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPK 1512
            AVNE      S++++   +        P V+   +N  +T    E   +   F G P P 
Sbjct: 1204 AVNEAGPGKPSDSSD--AITARPPPVKPKVDSSSRNREVTAVAGEKFRVEISFEGSPPPN 1261

Query: 1513 VTWYRDGKKLKTA----KATYENRXXXXXXXXXXX---XXXXYKCIAFNDHGEVETSCVV 1565
            +TW R  K   T     +  +E+                   Y     N+ G    +  +
Sbjct: 1262 ITWSRSDKNGITVEPSNRIAFEDTELSSIMANSEAERGDAGTYAVTFSNEKGTDTATVRI 1321

Query: 1566 GIQQKPVI---TISNEDI---------KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
             +  KP      ++  D+         K     G   +   VIE        W K    +
Sbjct: 1322 IVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTYV 1381

Query: 1614 ENDKEYNITTKEKTSVIRIK-ELKRSHSSKYTIEASNTAGTSSVEVTLK-VYDKPSKPEG 1671
                 Y++   ++ SV++ +   +  H     +E S         +T+K  +D P  P G
Sbjct: 1382 RT-TTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQA-------ITIKDPFDAPEAP-G 1432

Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
                 E+ R  V + W+ P  DGG  +  Y +EK E D   WI V D +    T  +  L
Sbjct: 1433 KPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERD-GEWIPVNDYNVKETTLPVGNL 1491

Query: 1732 NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
             +  EY FRV A+N  G   A  +   I  K  ++ PS          I  ++V + W  
Sbjct: 1492 RDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPS-APGVPVASDIGRDTVDLQWDK 1550

Query: 1791 SEKNGGSPIIDYKVEIKQEG 1810
               +GGS +  Y VE ++EG
Sbjct: 1551 PSSDGGSKLAGYVVEKREEG 1570



 Score =  101 bits (243), Expect = 2e-19
 Identities = 60/214 (28%), Positives = 96/214 (44%), Gaps = 6/214 (2%)

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
            T P  P  +  SE T  SV L W  PE +G S ++ Y +E +  K   WT+ VT      
Sbjct: 632  TAPGGPIEY--SEFTKESVRLTWKAPEQDGNSSVSGYSVERRDPKKDFWTR-VTSNAPTT 688

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
               ++++  +++ +FRI A N  G S P E + V+++     P  P+AP +I  +     
Sbjct: 689  SCVVKDLVYQNDYVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAP-KIDAMSRISA 747

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
              SW  P+ DGG+P+ GY +         W       +    + + +L E   Y  R+ A
Sbjct: 748  DLSWAPPDHDGGSPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIA 807

Query: 2044 RNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQT 2077
             N+ G  +P  S E   V+  +     + PG  T
Sbjct: 808  ANDAGEGKPSRSSE--SVVAKDPILPADAPGRPT 839



 Score =  101 bits (242), Expect = 2e-19
 Identities = 72/277 (25%), Positives = 114/277 (41%), Gaps = 8/277 (2%)

Query: 1747 VGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
            V FS    ++   ++   +D PS          +  +   ++W P + +GGS + +Y +E
Sbjct: 1306 VTFSNEKGTDTATVRIIVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVTNYVIE 1365

Query: 1806 IKQEGKK-W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
             +  G+  W K           +  L   +  +FR+ A N+ G   P      ITI    
Sbjct: 1366 KQAAGRSAWTKVSTYVRTTTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAITIKDPF 1425

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
              P  P      E     V L W  PE++GGSPI  YI+E +   G+ W  +        
Sbjct: 1426 DAPEAPGKPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERDGE-WIPVNDYNVKET 1484

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV--PSPPTAPLEIRMVGSN 1981
               + N+++  E  FR+ A+N  G   P     + +E  A +  PS P  P+    +G +
Sbjct: 1485 TLPVGNLRDTAEYEFRVFAKNKAGKG-PASRTLLGIEPKAIINAPSAPGVPVASD-IGRD 1542

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
             V   W  P  DGG+ L GY +  R+     W  V K
Sbjct: 1543 TVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPVSK 1579



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 61/279 (21%), Positives = 118/279 (42%), Gaps = 16/279 (5%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            V W K    ++ +++FT+ +     TL+       DQ  Y   L +++ +    + V+  
Sbjct: 569  VEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAERGDQGSYMIKLDNSRGSDSYSLNVLVL 628

Query: 1287 P-PKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
              P       EY    K    +T     Q        + V  +  KK   T+ + ++ + 
Sbjct: 629  DRPTAPGGPIEYSEFTKESVRLTWKAPEQDGNSSVSGYSVERRDPKKDFWTRVTSNAPTT 688

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADV----EMNVTI-LDKPSPPGKPNILEIDSSSIN 1398
            S  +K +   +  ++++   N  G ++     ++ V +  D+P  P  P I  +   S +
Sbjct: 689  SCVVKDLVYQNDYVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAPKIDAMSRISAD 748

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAV 1456
            + W  P++ G S +  Y+VE+   D  EW    +  I  T  ++ NL+  + Y+FR  A 
Sbjct: 749  LSWAPPDHDGGSPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIAA 808

Query: 1457 NEVDISDASETTEYYKVIKETKIQS-----PTVEKPLKN 1490
            N+      S ++E   V K+  + +     PT+EK  K+
Sbjct: 809  NDAGEGKPSRSSESV-VAKDPILPADAPGRPTLEKVTKD 846



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL------KVYDKPSKPEG 1671
            +YN+    K + + +  L+ +   ++ + A N AG      TL       + + PS P  
Sbjct: 1478 DYNV----KETTLPVGNLRDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPSAPGV 1533

Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
            PV   +I R++V ++W  P  DGG +L  Y +EK E  +  W  V+
Sbjct: 1534 PVAS-DIGRDTVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPVS 1578



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 9/136 (6%)

Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
           K+ N+   +E  + V AVN+ G     E S P   K K     P    + L+ + ++ G+
Sbjct: 198 KVDNLPVNKELEFRVAAVNKAGTGKPSECSAP--QKTKPKFARPTLKGDKLRDIKIKAGQ 255

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808
             +LS      P P I+W  N   V         +   +T +K K     D G Y LK  
Sbjct: 256 EFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKSDTGTYELKLT 315

Query: 809 NSEGIAETSAVITVEE 824
           N  G  +TS  + V++
Sbjct: 316 NDSGDVKTSCNVIVQD 331



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 10/157 (6%)

Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEP---LKSMIVRQGES 751
           +TN+   +E  + V A NR G +  S      +   + E P++      L  + ++ G  
Sbjct: 495 VTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSGFGLGDLRIKAGAR 554

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             ++   VG P P + W K+NK +K     T    +++S  +    +  D+G Y +K +N
Sbjct: 555 FDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAERGDQGSYMIKLDN 614

Query: 810 SEGIAETSA-VITVEEPTEENAEPPLFINRFQEITVK 845
           S G    S  V+ ++ PT      P+  + F + +V+
Sbjct: 615 SRGSDSYSLNVLVLDRPTAPGG--PIEYSEFTKESVR 649



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 5/124 (4%)

Query: 704  QEGTYTVVAVNRE--GEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVG 760
            +E  + V A N E  G+ S P    +   + E P++ I  L+ + V+ GE   ++  + G
Sbjct: 903  EELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTG 962

Query: 761  NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818
             P PT TW   + PVK           + T LK      +D G YT+  +N  G      
Sbjct: 963  FPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDAGRYTITVKNDSGSDTARV 1022

Query: 819  VITV 822
             +TV
Sbjct: 1023 KVTV 1026



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 1/128 (0%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            +E  + ++A N E   + SA        ++   P L I   ++I VK     ++   +T 
Sbjct: 903  EELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTG 962

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P+ TW   +  +  S  +         +L + + + + D+G Y     N +G  +  
Sbjct: 963  FPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQ-DAGRYTITVKNDSGSDTAR 1021

Query: 919  ARVTIDVE 926
             +VT+  E
Sbjct: 1022 VKVTVIAE 1029



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 1/127 (0%)

Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
           V  E  + + A N  G  + S     ++   + A P L  ++ ++I +K      L    
Sbjct: 204 VNKELEFRVAAVNKAGTGKPSECSAPQKTKPKFARPTLKGDKLRDIKIKAGQEFVLSVIF 263

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              P P I+W  N   ++ S+ +    + E  E+ +   D   D+G Y+   +N +G   
Sbjct: 264 EAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKS-DTGTYELKLTNDSGDVK 322

Query: 917 HGARVTI 923
               V +
Sbjct: 323 TSCNVIV 329



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 35/159 (22%), Positives = 64/159 (40%), Gaps = 14/159 (8%)

Query: 768 WCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
           W K   +PVK L        +++T L P +   E ++ + AEN  G++  S         
Sbjct: 480 WVKATREPVKTL-------AYTVTNLIPGR---EYLFRVFAENRAGLSTPSPESDHHVAK 529

Query: 827 EENAEPPLFINRFQ--EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            +   P +  + F   ++ +K      +       P P + W ++N+ + PS+  T +  
Sbjct: 530 AQFEAPKIDTSGFGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTT 589

Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             N  L+ +  +   D G Y     NS G  S+   V +
Sbjct: 590 ESNSTLLCSFAERG-DQGSYMIKLDNSRGSDSYSLNVLV 627



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 7/90 (7%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQT---AIIKPSQDFQMYYDDDNVATLVIR-EVFPEDAG 579
            G   + E   EG P P ITW R       ++PS   ++ ++D  +++++   E    DAG
Sbjct: 1245 GEKFRVEISFEGSPPPNITWSRSDKNGITVEPSN--RIAFEDTELSSIMANSEAERGDAG 1302

Query: 580  TFTCVAKNAAGFASSTTELI-VEAPLSDHG 608
            T+     N  G  ++T  +I V+ P +  G
Sbjct: 1303 TYAVTFSNEKGTDTATVRIIVVDKPSAPEG 1332


>UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole
            genome shotgun sequence; n=5; Euteleostomi|Rep:
            Chromosome undetermined SCAF9829, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 9369

 Score =  254 bits (623), Expect = 1e-65
 Identities = 151/476 (31%), Positives = 220/476 (46%), Gaps = 8/476 (1%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G +  + A ++G P P V W K    L  D    I T+   S + I    R  ++ Y 
Sbjct: 3168 RAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYI 3227

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            IEA N  G ++  + + + DKP  P    I  EI+ ES  + W PP DDGG  +T Y +E
Sbjct: 3228 IEAVNVCGRATATIDVNILDKPGPPAAFDIS-EITSESCCLAWNPPRDDGGSPITNYIVE 3286

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
              + D   WIK++   +   T+   KL    EY+FR+ A+N  G  E  E  PIV K + 
Sbjct: 3287 SRQTDKEEWIKLSATVKHT-TFKACKLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSF 3345

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW--KXXXXXXX 1821
            D P           I  ++V +TWF  +++GGSPI  Y VE    E +KW          
Sbjct: 3346 D-PPGSPTRVTPSDITKDAVTLTWFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKD 3404

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
               R++ L     Y+FR+ A N  G     +  D + I   + PP  P    V +    S
Sbjct: 3405 TSFRVKGLRTKKKYRFRVLAENLAGPGKASSETDPVLIKDPIDPPWAPGKPAVRDVGKTS 3464

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
              L WT PE +GG+ I  YIIEF+    + W   +     + EH ++ +KEK E  FR+ 
Sbjct: 3465 ALLAWTRPEHDGGAKIEGYIIEFQKTGSEEWV-CIAENVPLTEHQLQGLKEKQEYSFRVK 3523

Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
            A N  G S P+E     + K    P  P   LE+  +        W  P  DGG+P+  Y
Sbjct: 3524 AVNKAGESEPSEPSDPVICKERLYPPSPPQWLEVSNITRINAELKWQVPSSDGGSPITNY 3583

Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             +  RDV +  W  V    V  LK+ +  L+E   Y+ R+ A N +G+SE  E ++
Sbjct: 3584 VVEKRDVRRKTWQSV-DTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCELED 3638



 Score =  235 bits (575), Expect = 1e-59
 Identities = 186/735 (25%), Positives = 314/735 (42%), Gaps = 30/735 (4%)

Query: 1346 TIKKVENTDAGIYKLRLENNCG-----HADVEMNVTI-LDKPSPPGKPNILEIDSSSINI 1399
            T+  V      ++ +   N CG     + D  +N++     P PP      +  + SI +
Sbjct: 3012 TVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLKWRDKCAKSIFL 3071

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             W+ P+  G S +  YVV+  +  T +W    + + + +  +  L     Y +R  A N+
Sbjct: 3072 LWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQVSGLLEGQWYSYRVRAFNK 3131

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
            +  S  S  T+  + +   +     ++ K L  +T      IEL     G P P+V W +
Sbjct: 3132 LGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADVKGKPAPRVKWTK 3191

Query: 1518 DGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
                L+        T  +                Y   A N  G    +  V I  KP  
Sbjct: 3192 ADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATATIDVNILDKPGP 3251

Query: 1574 TISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
              +  DI +         W       G P    I      + + ++   ++   K +  +
Sbjct: 3252 PAAF-DISEITSESCCLAWNPPRDDGGSPITNYI--VESRQTDKEEWIKLSATVKHTTFK 3308

Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLKV-YDKPSKPEGPVIMREISRESVTIE 1686
              +L       + I A N  G       V +  K  +D P  P   V   +I++++VT+ 
Sbjct: 3309 ACKLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSFDPPGSPTR-VTPSDITKDAVTLT 3367

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W  P +DGG  +T Y +EK +P++ +WI+   +     ++ ++ L    +Y FRV+A+N 
Sbjct: 3368 WFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKDTSFRVKGLRTKKKYRFRVLAENL 3427

Query: 1747 VGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
             G  +A  E++P++IK  +D P           +   S  + W   E +GG+ I  Y +E
Sbjct: 3428 AGPGKASSETDPVLIKDPID-PPWAPGKPAVRDVGKTSALLAWTRPEHDGGAKIEGYIIE 3486

Query: 1806 IKQEG-KKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
             ++ G ++W            ++Q L     Y FR+ A N+ G S P    D +   + L
Sbjct: 3487 FQKTGSEEWVCIAENVPLTEHQLQGLKEKQEYSFRVKAVNKAGESEPSEPSDPVICKERL 3546

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
             PPS P+   VS  T  +  LKW  P S+GGSPITNY++E + V+ K+W  + T    + 
Sbjct: 3547 YPPSPPQWLEVSNITRINAELKWQVPSSDGGSPITNYVVEKRDVRRKTWQSVDTTVKDL- 3605

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNI 1982
            ++ +  + E    +FR++AEN+VG+S   E +   L K   T P PP A L +  V    
Sbjct: 3606 KYIVSPLNEGSLYVFRVAAENSVGMSEFCELEDAVLAKDTFTTPGPPYA-LTVLEVTKRH 3664

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            V   W  P+ DGG P+  Y I  ++   T W++  K      +F + D+ E      ++ 
Sbjct: 3665 VELKWEAPKSDGGRPITKYVIEKKEKLGTRWLKCCKTPDKQSQFKVTDVDEGSEVQFQVR 3724

Query: 2043 ARNEIGLSEPLESDE 2057
            A NE G+ +P E  E
Sbjct: 3725 AENEAGVGDPSEPTE 3739



 Score =  235 bits (574), Expect = 1e-59
 Identities = 185/748 (24%), Positives = 331/748 (44%), Gaps = 37/748 (4%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHS 788
            +E P+  + L ++   + +SV +  +V       +TW +  + +  +       DG    
Sbjct: 1925 EEAPKFTKNLSNVEGMETDSVKMICEV-SKASAEVTWYRGEEELPEVGRYEQIMDGRKR- 1982

Query: 789  ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            I I+K  +++D G YT +   +    +TSAV+ + E   E      FI+R Q   V E  
Sbjct: 1983 ILIIKGLRMEDAGQYTCRLSPN---IKTSAVLQLNELAAE------FISRPQNQEVVEGQ 2033

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
              +    V++     + W+R ++ +   +      +G+   L + N + + D G Y  VA
Sbjct: 2034 AAEFTCSVSKETY-EVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCELK-DEGGY--VA 2089

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEI 967
               A K+S    VT  +  +T +K      E +EG  ++  C+ +      KW  N++ I
Sbjct: 2090 HIGAIKASADLLVTEKLRVITPIKDT----EVKEGSEIVFNCEANAEGAKAKWLKNEETI 2145

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLV---VKETIPEFIRK 1022
                   + Q               D       + +Q  E +T      V E    F++ 
Sbjct: 2146 FETSKYMMAQRDNVFSLRIRDAQKTDEASYTVSLTNQRGEQATCTASAKVAEEKHRFLQP 2205

Query: 1023 LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
            ++D E +EK       ++N     V W + G+ +   K +  +   G    L I++  + 
Sbjct: 2206 IEDIETQEKKTISFVCKVNRPEVMVKWTKAGQEVALSK-RIVYRADGLKHTLTIKDCVME 2264

Query: 1083 DEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD 1142
            DEGEY+ ++ ++ CTA++ V E P +    L++Q V +   A F  +L K  A V+W+K+
Sbjct: 2265 DEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADFTCKLNKEKASVKWYKN 2324

Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL 1202
            G EI+      +  +GK  +L I +C  DD  EY+C +   +  A L VEE  +   +R 
Sbjct: 2325 GREIREGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTRARLFVEETPVEI-IRP 2383

Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
            P+ +L P  +D    VE+  + ++V W +   +I   +K+ +IS+ K   L + +    D
Sbjct: 2384 PQDMLEPPASDIVFEVELNKDRVEVKWMRNNMIIVQGDKYQMISEGKIHRLQVCEIRPRD 2443

Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
            Q EY  V  D  +  KL++  V   PKI   +++     G    + V Y A+P+   EW 
Sbjct: 2444 QGEYRIVAKDKDARAKLELAAV---PKIKTTDQKLVTDAGKPFIMRVPYDAYPRAEAEWF 2500

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
                 +   ++   S+D       +K     D G YK+ + N  G A+  + + ++D P 
Sbjct: 2501 FEDTSL-PVQNIDTSVD--KTEYRLKSPSKEDQGQYKVVISNKHGAAEAFIVLDVIDVPG 2557

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQ 1441
                  +L+     +++ W+EPE+ G S II YVVE +++    W ++       +  + 
Sbjct: 2558 SVKNLRVLDTADGEVSLAWEEPESDGGSKIIAYVVERRDVKRKTWALATDRADTPEYCVT 2617

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTE 1469
             L  +S+Y FR  A N V    A  T +
Sbjct: 2618 GLHKDSAYLFRVCARNRVGSGPAVVTED 2645



 Score =  230 bits (563), Expect = 3e-58
 Identities = 229/868 (26%), Positives = 376/868 (43%), Gaps = 62/868 (7%)

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            +W  DG +I       +   G    L I +C   D GEY   V N   +  + +    ++
Sbjct: 6544 KWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYVLIVTNPAGSKTVALHVTVLD 6603

Query: 1198 FTLRLPEFILVPANTDAYLTVE--IP--DETLDVTWY--KKKSVIEDTEKFTLISDVKKR 1251
                    I +   T  Y+ ++   P  D    +T Y  +KK V +  E ++++S     
Sbjct: 6604 LPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVKKPWEPWSVVSSSGTN 6663

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG----SDVT 1306
            T       E  + EY   ++  ++  K+ +   +E PP I  +        G    SD+T
Sbjct: 6664 TKAKVSRLEKGR-EY---VVRVRAENKIGISTGLESPPTIAKHMFNPPGPPGLPVCSDIT 6719

Query: 1307 ---LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIK-KVENTDAG-IYKL 1360
               + V++   P  +    ++  +I++ + T   I  +K+  L ++ +V     G  Y+ 
Sbjct: 6720 ENAVTVEW-TLPDYDGGSPISGYVIERREMTGKWIRVNKTPVLDLRYRVSGLFEGNSYEF 6778

Query: 1361 RL--ENNCGHADVEMN------VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
            R+  EN  G +D  +          + +P PPG P + +   S  +ICW +P   G S +
Sbjct: 6779 RVFAENIAGISDPSLASDPVKAARAITRPGPPGNPKLRDWSKSYADICWTKPTRDGGSPV 6838

Query: 1413 IYYVVEYQEIDTTEWISV-KNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            + YVVE Q+  + +W  + K++ K     +  L     YRFR  A N+V  S+  E  E 
Sbjct: 6839 LGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRIRAANKVGESEPRELAE- 6897

Query: 1471 YKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
              V+ +  +  P  TV+   ++  T   + I L  I+   P+    W R  K     K T
Sbjct: 6898 -TVLAKDILVPPEVTVDVSCRDALTIRADQI-LNLIYEKKPKSSEEWERLHKG--AIKET 6953

Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH---- 1584
            Y                  ++    N+ GE        +  K  I      IK       
Sbjct: 6954 Y-----FMADRCIENQIYQFRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVV 7008

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT--SVIRIKELKRSHSSK 1642
            K GD   + A+++G P P+V W K+ +  E  K   +  +  T  S + +   +R+ S K
Sbjct: 7009 KAGDSIPIEAMVKGKPQPDVKWTKDNSTEEIKKGPRVQIENGTDFSKLLLTGARRTDSGK 7068

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y I  +N+AG+ S   T+ V D+P  P   + +  IS +   + W+ P D+GG ++  Y 
Sbjct: 7069 YVIAVTNSAGSCSAFATVSVLDRPG-PVQDLKVSGISIDRCHLAWEAPEDNGGCDIYNYI 7127

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            IEK E     W   ++     +T  + +L E  EY+FRV A+N +G   A++SEPIV  T
Sbjct: 7128 IEKCETKRGVWSVHSNAVITNKTK-VTRLIEGNEYIFRVRAENKMGPGPAVQSEPIVAGT 7186

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXX 1821
               VP           I  E + + W   EK+GG PI  Y +E ++E   +W        
Sbjct: 7187 QFSVP-YAPEMPEVTKIAKEEMTVQWSEPEKDGGKPITGYLLEKREEHAVRWSPVNKDPT 7245

Query: 1822 XXARIQKLSINTT--YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
                     +     YQ+R+ A NEIG S P  S   +T    + PP+ P N  V +ST 
Sbjct: 7246 PATHFTVTGLIPLHDYQYRVKAVNEIGISSPSKSSRAVTAKDAVGPPAPPSNLRVLDSTK 7305

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFK----TVKGKSWTKIVTVGGS--VHEHCIENIKEK 1933
             +VTL WT+P S GG+PI  Y++E +      KG    K   V     V +  + ++ ++
Sbjct: 7306 STVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQLVVCDFTVTSLDDQ 7365

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEK 1961
                FR+SA+N VG+SLP + +   + K
Sbjct: 7366 LVYEFRVSAQNQVGMSLPCDLKDAVIPK 7393



 Score =  229 bits (561), Expect = 5e-58
 Identities = 170/691 (24%), Positives = 291/691 (42%), Gaps = 27/691 (3%)

Query: 1282 EVVEFPPKIVDYERE--YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
            +++  P  ++  E +    +  G+ + L    +  P+P   W   +  IK  +       
Sbjct: 8232 DIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITWAKMNTNIKDRQGIVIKSS 8291

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
            +    + ++ V   DAG Y   LE+  G     + V + D P PP    + E      +I
Sbjct: 8292 NTDTIVMVENVNRYDAGKYIFNLESLAGMKMYTIVVKVYDTPGPPVNLMVKETSKDGASI 8351

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             WD P   G   + +Y+VE ++ +   W  V  N  KT   + +L    SY FR   V+ 
Sbjct: 8352 FWDSPLTDGGYEVTHYIVEKRDTERKAWSIVSMNCNKTSFEVPDLNAGRSYCFR---VSG 8408

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDIELTCIFGGVPQPKVTWYR 1517
            V+   A E  E    ++ +  + P      K +  T+ +  I             +++  
Sbjct: 8409 VNKLGAGEYCETADSVRAS--EEPGAVMDFKTVLVTKDSCTISWKKPLSDGGSRIISYVL 8466

Query: 1518 D--GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            +      K  +                     Y+  A ND GE     +  + +  +I  
Sbjct: 8467 EVLNGDDKYKELMRSKNMQYSAKDLVEGKEYTYRVKAINDSGEGAAKELTVVAKDQIIH- 8525

Query: 1576 SNEDIKQKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTS 1628
             N D+++        K G    +   I G P P+V W K  ++ L++       +    +
Sbjct: 8526 PNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDDEDLKDSGRVCAESSSVNT 8585

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             + I++ +R+ +SKYTI   N+AG     + ++V  KP  P GP+  ++++ +  T++W 
Sbjct: 8586 TLLIRDCQRNDASKYTITLRNSAGIKESTIFIRVVGKPGIPVGPIKFKDVTADGATLKWG 8645

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
             P DDGG ++  Y +EK +   N W+ V+    +  +  +  L+E  EY+FRV A+N  G
Sbjct: 8646 APKDDGGSDIANYILEKRDSVTNMWVTVSS-SVETNSMRVTGLHEGTEYIFRVCAENKYG 8704

Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
              E L+S+PI+ K   +VP           + + S Y+ W    K GGSPI  Y +E K+
Sbjct: 8705 VGEGLKSDPIIAKHPFNVPE-APPPPQIMNMQHNSAYLAWLDPRKTGGSPITGYHLEFKE 8763

Query: 1809 EGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
                 WK             +  L+    Y+FR+ A N  G   P    D       +  
Sbjct: 8764 RNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRVMAINLAGIGKPSAPTDPRVALDPIDV 8823

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P +P    +++ST   VTL+W EP+ +GG  +T YIIE + +  K W K   V       
Sbjct: 8824 PGKPEVISITKST---VTLQWIEPQFDGGHRLTGYIIEKRDLPSKIWMKANNVNVLEPAF 8880

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
             + +++E  +  FRI A+N  G   P   Q+
Sbjct: 8881 TVMDLQEGCKYEFRIRAKNAAGAISPASEQT 8911



 Score =  229 bits (560), Expect = 6e-58
 Identities = 204/857 (23%), Positives = 363/857 (42%), Gaps = 67/857 (7%)

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIV-DYEREYRIKRGS 1303
            +++  + ++I      D   +  +   A ST ++   +   P PK+   ++     ++ +
Sbjct: 5196 AEILTQDILIEPTVTLDVSAHDLLNCRADSTIRIPATITGRPLPKVTWTFDGTAETEKKN 5255

Query: 1304 DVTLL-VDYQAFPQPNDEWIVNS--KIIKKCKHTKPSIDSKSAS--LTIKKVENTDAGIY 1358
            D+ +L VD +  P    E I ++  K +    H    I S   +  +TI   +   +G Y
Sbjct: 5256 DLHILPVDSEVRPFSLGELIYHNAFKSLTLFPHVSFQIHSSDTTSVVTIPISKLAHSGRY 5315

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             +  E+  GH  V++ VT+LD P PP    + ++   +  + W  P+  G   +  Y +E
Sbjct: 5316 IINAESPAGHKVVKVRVTVLDLPGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIE 5375

Query: 1419 YQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE- 1476
             + +    W  V      Q+ +  +L     Y FR  A N       ++T E  K     
Sbjct: 5376 KKTVHGKAWTKVNPACAAQSLVVPDLNNGQEYLFRIRAENRFGFGPFTQTIERTKASDPI 5435

Query: 1477 ------TKIQSPTVEKPLKNITTE-PNED---------IELTCIFGGVPQPKVTWYRDGK 1520
                  T+++   V K    +T + P  D         ++L C      Q K  W R  +
Sbjct: 5436 NPPDPPTRLKIQNVHKGAVTLTWKAPKNDGGSPVTHYSVDLLCWDASGTQ-KEHWRRCNR 5494

Query: 1521 K-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQ-QKPVITI 1575
            + +++ +   E+                ++ +A+N+ G    S   G   IQ Q    +I
Sbjct: 5495 RDVESTRFKVED--------LTYGDEYEFRVVAYNEAGPSRPSTTAGPITIQDQSCAPSI 5546

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-----NGNKLE--NDKEYNITTKEKTS 1628
              ++  +  + G +  + A I G P P + WYK     + NK+E   D+  N    + + 
Sbjct: 5547 ELQEFMEVEQ-GSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSC 5605

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             + I++ KR  +  YT+ ASN+ G +S E+ L V  +P  P  P+   EI  E +T+ W 
Sbjct: 5606 TLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNVLGRPGPPSAPIKFEEIGAERITLSWL 5665

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
            PP DDGG ++T Y I +   +   W+ V    ++   + ++ L    EY+FRV+AQN  G
Sbjct: 5666 PPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKE-RIWTVENLMTGHEYVFRVMAQNKYG 5724

Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
              E L+SEP V +     P           +D ++           G   II Y      
Sbjct: 5725 VGEPLDSEPEVARDLYIGPE----------VDLDTSVKEKMVVHAGGVIRIIAYVSGQPT 5774

Query: 1809 EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYTSDDK--ITIGKT 1862
                W          A+++   I++    +  +R  +G    T+     + K  +T+   
Sbjct: 5775 PDITWSRDGSALPPEAKVETTFISSALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVL 5834

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
              P      F     ++ S  L W  PE++GGSPI+NYI+E +  + K+WT  V+   S 
Sbjct: 5835 DVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIVEKREAERKAWTS-VSFTASR 5893

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSN 1981
                   +       FR++AEN +G+    E+ + V + +  ++P  P   LE+  V  +
Sbjct: 5894 TNAVAHGLTSGKSYFFRVAAENAIGIGPFVETAAEVVIREPISIPERP-EELEVHKVTKD 5952

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
            ++  +W  P+ DGG+ +  Y +  R + K  +  + K  +   K+    L E  TY  R+
Sbjct: 5953 LISVTWKPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRV 6012

Query: 2042 YARNEIGLSEPLESDEP 2058
             A NE+G  +P    +P
Sbjct: 6013 IAVNEVGPGKPSFCTKP 6029



 Score =  206 bits (503), Expect = 5e-51
 Identities = 214/942 (22%), Positives = 380/942 (40%), Gaps = 64/942 (6%)

Query: 766  ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            + W K+ K   P K +   +DG    +T+ K +K  + G YT       G  +T+A + +
Sbjct: 1513 VKWFKDGKELTPSKNIAIITDGKKRILTVRKAEKA-NIGEYTCDC----GSDKTTAKLNI 1567

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            EE   +   P         + V E  T K    ++ + V    W    E +  S  +   
Sbjct: 1568 EERDIKIVRP------LYSVEVTETETAKFETEISEDDVHG-NWKLKGEALQQSADVEMK 1620

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             +G    LV+ NV  ++ +G     A+N+  +SS  A++ +    V  V+ L K      
Sbjct: 1621 EEGTRHMLVLYNVHMDM-AGAVDFSAANA--RSS--AQLRVKARSVGLVRPL-KDVMVTA 1674

Query: 943  GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            G+T   EC+ S+  +  +W+   +++   +  +    GR            + G +K   
Sbjct: 1675 GETATFECELSYEGIVVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTA 1734

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
            KD +T   L+VKE   EF + L+D  V+E     LE  ++ E A+V W RDG+ ++ K  
Sbjct: 1735 KDFQTQAHLIVKEPPVEFTKPLEDQTVEEDSTVTLECAVSRENAEVRWFRDGQELR-KTK 1793

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
            K+D    G  R L I N S  D   Y+C  +D   +  + V     E    LQ+ +V + 
Sbjct: 1794 KFDLLSLGCKRMLVIHNCSSEDIKMYTCDTKDFKTSCYLDVTPPHVEFTKLLQDVEVRER 1853

Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              A FE E+++  A VRWFKDGSEI+     ++T  G ++ L I+    DD  EY C+  
Sbjct: 1854 EAAKFECEVSRESAKVRWFKDGSEIRKGKKYEITASGVQRTLIIHKSGFDDEAEYECDAR 1913

Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAY-LTVEIPDETLDVTWYKKKSVIEDTE 1240
             SK + +LTV E +  FT  L    +    TD+  +  E+   + +VTWY+ +  + +  
Sbjct: 1914 TSKTSGLLTVIEEAPKFTKNLSN--VEGMETDSVKMICEVSKASAEVTWYRGEEELPEVG 1971

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300
            ++  I D +KR LII+    +D  +YTC  L     T   +++ E   + +   +   + 
Sbjct: 1972 RYEQIMDGRKRILIIKGLRMEDAGQYTC-RLSPNIKTSAVLQLNELAAEFISRPQNQEVV 2030

Query: 1301 RG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             G  ++ T  V  + +     +W    K ++         + K   LT+K  E  D G Y
Sbjct: 2031 EGQAAEFTCSVSKETY---EVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCELKDEGGY 2087

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
               +      A  ++ VT   +   P K    E+   S  I ++   N   +   +   E
Sbjct: 2088 VAHI--GAIKASADLLVTEKLRVITPIKDT--EVKEGS-EIVFNCEANAEGAKAKWLKNE 2142

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
                +T++++  +        I++ +      +     N+    + +  T   KV +E  
Sbjct: 2143 ETIFETSKYMMAQRDNVFSLRIRDAQKTDEASYTVSLTNQ--RGEQATCTASAKVAEE-- 2198

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538
                   +P+++I T+  + I   C     P+  V W + G+++  +K            
Sbjct: 2199 --KHRFLQPIEDIETQEKKTISFVCKVNR-PEVMVKWTKAGQEVALSK-------RIVYR 2248

Query: 1539 XXXXXXXXXYKCIAFNDHGEV-----ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                      K     D GE      E  C   +            +K +     E    
Sbjct: 2249 ADGLKHTLTIKDCVMEDEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADF 2308

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT--IEASNTA 1651
                      V WYKNG ++     Y++  + K   + IKE +     +Y   ++   T 
Sbjct: 2309 TCKLNKEKASVKWYKNGREIREGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTR 2368

Query: 1652 G-----TSSVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEW 1687
                   + VE+     D    P   ++   E++++ V ++W
Sbjct: 2369 ARLFVEETPVEIIRPPQDMLEPPASDIVFEVELNKDRVEVKW 2410



 Score =  205 bits (501), Expect = 9e-51
 Identities = 137/451 (30%), Positives = 209/451 (46%), Gaps = 17/451 (3%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVE-----VTLK-VYDKPSKPEGPVIMREIS 1679
            K +  R+K L+     ++ + A N AG          V +K   D P  P  P + R++ 
Sbjct: 3403 KDTSFRVKGLRTKKKYRFRVLAENLAGPGKASSETDPVLIKDPIDPPWAPGKPAV-RDVG 3461

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
            + S  + W  P  DGG ++  Y IE  +  +  W+ +A+ +  +  + +Q L E  EY F
Sbjct: 3462 KTSALLAWTRPEHDGGAKIEGYIIEFQKTGSEEWVCIAE-NVPLTEHQLQGLKEKQEYSF 3520

Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            RV A N  G SE  E S+P++ K  L  PS          I   +  + W     +GGSP
Sbjct: 3521 RVKAVNKAGESEPSEPSDPVICKERLYPPSPPQWLEVSN-ITRINAELKWQVPSSDGGSP 3579

Query: 1799 IIDYKVEIKQEGKK-WKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
            I +Y VE +   +K W+           I   L+  + Y FR+ A N +G S     +D 
Sbjct: 3580 ITNYVVEKRDVRRKTWQSVDTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCELEDA 3639

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            +    T T P  P    V E T R V LKW  P+S+GG PIT Y+IE K   G  W K  
Sbjct: 3640 VLAKDTFTTPGPPYALTVLEVTKRHVELKWEAPKSDGGRPITKYVIEKKEKLGTRWLKCC 3699

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEI 1975
                   +  + ++ E  E+ F++ AEN  GV  P+E ++ + +E   + PSPP   L I
Sbjct: 3700 KTPDKQSQFKVTDVDEGSEVQFQVRAENEAGVGDPSEPTEILNIEDPTSAPSPP-LDLTI 3758

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM-WMEVGKVDVNTLKFNIRD-LSE 2033
                   +  +W  P  DGG P+ GY++ + +    + W+ V    +  LKF I D +  
Sbjct: 3759 PDASREHITATWKPPAKDGGCPISGYHVEVAEARPELKWLRVNNRPIKELKFRIDDGIKP 3818

Query: 2034 NHTYMIRIYARNEIGLSEPLE-SDEPFKVIP 2063
               Y+IR+ A N +G  +P E +D+ F   P
Sbjct: 3819 EKKYVIRVRAINSVGTGDPSEITDKIFTKDP 3849



 Score =  195 bits (475), Expect = 1e-47
 Identities = 190/802 (23%), Positives = 321/802 (40%), Gaps = 48/802 (5%)

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-------NSKIIKKCKHTKPSIDSKSA 1343
            ++ +    +++GSD++++   +  P P   W         N   ++  +H    +   S 
Sbjct: 5546 IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSC 5605

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWD 1402
            +L I++ +  D G+Y L   N+ G A  EM + +L +P PP  P    EI +  I + W 
Sbjct: 5606 TLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNVLGRPGPPSAPIKFEEIGAERITLSWL 5665

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDI 1461
             P++ G S +  YV+  +  +   W+ V +  K +  +++NL T   Y FR  A N+  +
Sbjct: 5666 PPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKERIWTVENLMTGHEYVFRVMAQNKYGV 5725

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPL---KNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
             +  ++    +V ++  I  P V+      + +       I +     G P P +TW RD
Sbjct: 5726 GEPLDSEP--EVARDLYI-GPEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRD 5782

Query: 1519 GKKLKTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV--- 1572
            G  L   +A  E                    Y   A N  GE + +  V +   P    
Sbjct: 5783 GSALPP-EAKVETTFISSALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVLDVPGPVG 5841

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            I  + E++         W       G P    I  K   + +     + T     +V   
Sbjct: 5842 IPFTTENLSND-SCKLNWFFPENDGGSPISNYIVEKREAERKAWTSVSFTASRTNAVAH- 5899

Query: 1633 KELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKP--SKPEGP--VIMREISRESVTIEW 1687
              L    S  + + A N  G    VE   +V  +   S PE P  + + +++++ +++ W
Sbjct: 5900 -GLTSGKSYFFRVAAENAIGIGPFVETAAEVVIREPISIPERPEELEVHKVTKDLISVTW 5958

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            KPP  DGG E+T Y +E      +++ ++         Y    L E   Y FRVIA N V
Sbjct: 5959 KPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRVIAVNEV 6018

Query: 1748 GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIIDYK-- 1803
            G  + +  ++PI  K  L+ P+          I   ES  +    + K   S I  Y+  
Sbjct: 6019 GPGKPSFCTKPITCKDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPS-IAWYRDD 6077

Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
             E+K + K              + K     + ++ +   N  G+     +   +T+    
Sbjct: 6078 EEVKAD-KHVMFKNTLTTMSLGLMKAQREHSGRYVVVVENSTGSRKGICN---VTVVGVP 6133

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG-GSV 1922
              P  P    V E  + +  + W  P  +GG PITNYI+E K    K W++         
Sbjct: 6134 EAPEMP---TVREVYATNALVLWNRPR-DGGKPITNYILEKKETMAKRWSRATREPLYPA 6189

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGSN 1981
             +  ++++ E  E  FR+ AEN +G   P+E     L K   V PSPP  P E      +
Sbjct: 6190 TQFRVQDLVEGCEYEFRVMAENELGTGDPSEPSKPILAKDPIVCPSPPVTP-EAYDKTKD 6248

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK--VDVNTLKFNIRDLSENHTYMI 2039
             V   W  P  DG   + GY +  +      W++  +       L F +  L++   Y+ 
Sbjct: 6249 SVSLKWKLPRHDGKGRIFGYLVEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVF 6308

Query: 2040 RIYARNEIGLSEPLESDEPFKV 2061
            RI+  N  G S+P    EP KV
Sbjct: 6309 RIFTVNAAGKSDPAYIREPIKV 6330



 Score =  194 bits (472), Expect = 3e-47
 Identities = 185/711 (26%), Positives = 291/711 (40%), Gaps = 50/711 (7%)

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            VVEF   +   ++   I+ G  + L       PQP  +W  +   I K +    + + K+
Sbjct: 4502 VVEFDASV---KKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMIVET-EGKN 4557

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            +SL IKK   TD G YK+   N+ G    E  V I+D P P      + +   +I + W 
Sbjct: 4558 SSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVPGPVVDLKTVTVTKKNITLTWS 4617

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            +P + G S II Y V  ++     +         +  IQ L     Y FR  A N+    
Sbjct: 4618 DPHDNGGSDIIGYDVLRKDAKMKLFRHPMETASCKCDIQGLLAGEEYDFRVIARNKYGDG 4677

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC----IFGGVPQPK--VTWY 1516
              S+      ++ +    +P+  + L + T      I L        GG P     V   
Sbjct: 4678 APSDLGP---ILAQDPKGTPSAPEKL-HYTDRGKTTIMLAWQPPRTDGGSPIRGYYVEKM 4733

Query: 1517 R-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQK--- 1570
            R D  + + A                      ++  A N+ G+ E S  +   IQ     
Sbjct: 4734 RSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELA 4793

Query: 1571 PVITI-----SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624
            PVITI     SN  I +K    D   + A ++G+P P + W K+   +E   E  +  + 
Sbjct: 4794 PVITILKFFKSNAIIIKKGSAID---IPAEVKGLPLPSLQWVKDDVVIETPVEDKMIMET 4850

Query: 1625 ---EKTSV---IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
               ++T++   I I E  R     Y + A N  G +   + +++ D+P  P   V++ +I
Sbjct: 4851 EEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFGKAQHVIRVEILDRPLPPRN-VVVSDI 4909

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEY 1737
              +S  + W  P D+GG E+T Y IE+ +    +   +V   +     Y + KLN N  Y
Sbjct: 4910 KADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQTTNLIDRRYGVYKLNVNGAY 4969

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             FR+ A+N  G S+  +SE + +     +P               ++ +TW P   NGGS
Sbjct: 4970 QFRIKAENKYGISDGCDSEKVQLSDPFGLPGPPRNPKIIAATAT-TMTLTWDPPLDNGGS 5028

Query: 1798 PIIDYKVEIKQEGKK-WKXXXXXXXXXARIQ-------KLSINTTYQFRIYARNEIGTSL 1849
             I  Y +E ++ G   W            ++       KL   T YQFRI A N  G   
Sbjct: 5029 TIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAGVGP 5088

Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
            P  + +         PPS P    V + T  S+TL W+ P+ +GGSP+  YIIE      
Sbjct: 5089 PSEASECRFAVDPCNPPSSPGAPEVKDKTKNSITLSWSPPDKDGGSPVKGYIIEVHEEGC 5148

Query: 1910 KSWTKIVTVGGSVH---EHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
              W + V     +H   E  + ++KE  +  FRI A N  G S P  +  +
Sbjct: 5149 PDWRR-VNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAEI 5198



 Score =  188 bits (459), Expect = 1e-45
 Identities = 110/396 (27%), Positives = 186/396 (46%), Gaps = 6/396 (1%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G   ++ A + GIP P   W  +G  + ++   +I T   ++++ I E +R  + +Y 
Sbjct: 6524 KAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYV 6583

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            +  +N AG+ +V + + V D P  P GP+ + E++ + + I+W+ P DDGG  +T Y +E
Sbjct: 6584 LIVTNPAGSKTVALHVTVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVE 6643

Query: 1705 KHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            K +       W  V+    + +   + +L +  EY+ RV A+N +G S  LES P + K 
Sbjct: 6644 KKDVKKPWEPWSVVSSSGTNTKAK-VSRLEKGREYVVRVRAENKIGISTGLESPPTIAKH 6702

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW--KXXXXXX 1820
              + P            +N +V + W   + +GGSPI  Y +E ++   KW         
Sbjct: 6703 MFNPPGPPGLPVCSDITEN-AVTVEWTLPDYDGGSPISGYVIERREMTGKWIRVNKTPVL 6761

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                R+  L    +Y+FR++A N  G S P  + D +   + +T P  P N  + + +  
Sbjct: 6762 DLRYRVSGLFEGNSYEFRVFAENIAGISDPSLASDPVKAARAITRPGPPGNPKLRDWSKS 6821

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
               + WT+P  +GGSP+  Y++E +      W +I      +  + +  + E  E  FRI
Sbjct: 6822 YADICWTKPTRDGGSPVLGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRI 6881

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
             A N VG S P E     L K   VP   T  +  R
Sbjct: 6882 RAANKVGESEPRELAETVLAKDILVPPEVTVDVSCR 6917



 Score =  179 bits (436), Expect = 7e-43
 Identities = 131/434 (30%), Positives = 197/434 (45%), Gaps = 18/434 (4%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKV----YDKPSKPEGPVIMR--EISRESVT 1684
            R+K + +  + +Y +E  N   T  V++ + +    +D   KP+ P+ +   + + +S+T
Sbjct: 4059 RVKAVNKVGAGQY-LELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKSIT 4117

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            I WK P +DGG  +  Y +EK E D +R+ +V        ++ +  L EN EY FRV A+
Sbjct: 4118 ITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVRAE 4177

Query: 1745 NPVGFSEALESEPIVIKTA--LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            N  G SE   S  + +K A  +D P           I N SV   W P E +GGS I++Y
Sbjct: 4178 NVAGVSEPSRSTQL-LKAADPVDKPGAPINFTFDE-IRNTSVICNWEPPEDDGGSEILNY 4235

Query: 1803 ---KVEIKQEGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
               K + K+E   W          +  + KL     Y FR+ A N+ G   P  S   +T
Sbjct: 4236 ILEKRDYKKEEVGWITITSTLKGNSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGP-LT 4294

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
                  PP  P    V E T+ +  L W EP+ NG SPI  Y IE K V  K WT++   
Sbjct: 4295 AKNQFDPPDAPNTPRVHEVTASTARLSWHEPKDNG-SPILGYWIERKEVNSKHWTRVNRA 4353

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
              +  E  + N+ E    IFR+ AEN  G    +E         A +P  P  P  +   
Sbjct: 4354 LINSLEVKVSNLMEGLTYIFRVCAENLAGPGPFSEPSDRTTAMDAILPPGPPTPWIVD-T 4412

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
            G + V+ +W  P ++GG  +LGY++      +  W    +     L F +  L E   Y 
Sbjct: 4413 GKDFVIVAWKPPLYNGGGDILGYHVEKVLAGEKEWTRSTEFRCKDLTFTVTGLIEGADYY 4472

Query: 2039 IRIYARNEIGLSEP 2052
            IR+ A N+ G   P
Sbjct: 4473 IRVVAINDAGPGAP 4486



 Score =  179 bits (435), Expect = 9e-43
 Identities = 180/704 (25%), Positives = 296/704 (42%), Gaps = 40/704 (5%)

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            VA N  G   + T  I  A   D G+                  +LE I     K  + Q
Sbjct: 677  VAINIIGLQHAVT--IQNATEEDTGAYTCEVEGREDISTTTNVKVLEIIKDWLVKPLRDQ 734

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAIESDMHMYCSVLKITNVKK 702
            +V   S    +  L     P+  WL KGE EI P E + +A +         L I N + 
Sbjct: 735  HVKPKSKATFKGELFK-DTPNWKWL-KGETEITPSEKMEIAKDGAN----VTLTINNCQP 788

Query: 703  FQEGTYTVVAVNREGEASLPI--VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
                 YT+   +R   A L +   ++ +  E+E  ++++PL S+ V + E      ++  
Sbjct: 789  DDVSEYTIEVEDRRYTAKLTLGGAVRRRFQEREA-EILKPLASLEVVEKEEANFDTEI-- 845

Query: 761  NPRPTI-TWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            +    I  W    + +   PT   K +G    +T LK  +V   G  + +A N    A T
Sbjct: 846  SEEDIIGEWKLRGQVLTRSPTCDIKLEGRKRFLT-LKNVQVDQAGEVSYQALN----AVT 900

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            + ++TV+E  E       F++  ++++V EK   K    VT+  VP + W++  EI++P 
Sbjct: 901  TGMLTVKE-LEMG-----FVDPLKDVSVPEKKQAKFECTVTKE-VPKVMWFKGAEIVTPG 953

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
                   DG    LVI + + + D   Y          S    ++ ++  ++ FV+ LQ 
Sbjct: 954  PKYEIIDDGLKHMLVINSCEFD-DEAQYTIEVLGQRSSS----QLRVEGIRLNFVQPLQD 1008

Query: 937  SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                +EGKT   E + +H  V   WY N+ ++       +  EG+            D  
Sbjct: 1009 Q-TVKEGKTAHFELELTHDNVPVLWYRNEVKLHVSRTVLMHVEGKKHRLEMRTVSLDDTC 1067

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEI 1055
             IK   K   +   L V E    F+ KLQDF   EKD  +L  E+ S+   VVW    + 
Sbjct: 1068 QIKAEAKGIYSVAQLTVVEGDAVFVVKLQDFAATEKDELLLSCEL-SKDVPVVWYHSEKE 1126

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115
            I   K     +  G  R L ++      +G Y+C    +  +A V V     +I+  L  
Sbjct: 1127 ITASKTVV-LKSEGTCRSLLLKRVEQSSKGTYTCDCGTDKTSAVVDVQARDVKIVRPLYG 1185

Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
             ++  G  A FE+E+++ D   +W  +G  +  S  + +  DG K  L +Y+C +  AGE
Sbjct: 1186 VELFDGETARFEVEISEDDVRGQWKLNGDVLSRSPDVDIIEDGSKHTLILYNCRVAMAGE 1245

Query: 1176 YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235
             +    N+KC+A L V+E  +NF   L + + V    +A   VE+        W K    
Sbjct: 1246 VAYTAANAKCSAKLKVKELPLNFLTSLND-VQVYEKDEARFEVELSRPPKSFRWLKGSQE 1304

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            ++  EK+ LI +     L+IR    +D+ +Y     D ++  KL
Sbjct: 1305 LQSDEKYELIQEGHTYVLLIRSAIYEDEAKYMFEAEDKRTACKL 1348



 Score =  174 bits (424), Expect = 2e-41
 Identities = 118/387 (30%), Positives = 168/387 (43%), Gaps = 8/387 (2%)

Query: 1585 KVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            + GD  ++TA  I G P P   W K G   +      I T   +S + IK   R  + +Y
Sbjct: 8938 RAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRKDTGEY 8997

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
             I ASN  G     V + V D P  P GP+    IS E V + W  P ++GG  +  Y +
Sbjct: 8998 VITASNPFGVKEETVKVTVLDVPDSP-GPIECSGISSEKVALSWTAPTENGGSPIKYYTL 9056

Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            EK E     W  + +   D   Y   KL +  EY FRV A N  G SE   SE + +   
Sbjct: 9057 EKRETSRLLWTVLEEKVVDCH-YVAYKLIQGNEYFFRVSAVNQYGASEPSHSEAVKMVDR 9115

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX 1822
               P           +D  S  +TW     +GGS II Y VE K++ G +W         
Sbjct: 9116 FGPPGPPSKPEVEK-VDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRASKKSIA 9174

Query: 1823 XARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                Q   L+ +  Y+FR++A N  G   P      +       PP  P N  ++++T  
Sbjct: 9175 ELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNPRITDTTKT 9234

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
            + TL W +P  NGG  IT Y+IE K    + W K       + E  +  ++   +  FRI
Sbjct: 9235 TATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAKYHFRI 9294

Query: 1941 SAENTVGVSLPTE-SQSVRLEKHATVP 1966
            SA N+ G   P E S+ V + + A+ P
Sbjct: 9295 SAVNSKGAGEPAETSELVEIIERASEP 9321



 Score =  173 bits (421), Expect = 4e-41
 Identities = 120/398 (30%), Positives = 183/398 (45%), Gaps = 27/398 (6%)

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
            +I++ S  + W+ P DDGG  ++ Y +E+ E     ++ V   + +V T+ ++ L  NCE
Sbjct: 3997 DITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLSGE-NVLTHTVKDLYVNCE 4055

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX-------------IDNES 1783
            Y FRV A N VG  + LE    VI   + +P                          ++S
Sbjct: 4056 YFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKS 4115

Query: 1784 VYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXX--XXXARIQKLSINTTYQFRIY 1840
            + ITW   + +GG PI  Y VE I+++G +++             +  L  N  YQFR+ 
Sbjct: 4116 ITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVR 4175

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N  G S P  S   +     +  P  P NF   E  + SV   W  PE +GGS I NY
Sbjct: 4176 AENVAGVSEPSRSTQLLKAADPVDKPGAPINFTFDEIRNTSVICNWEPPEDDGGSEILNY 4235

Query: 1901 IIEFKTVKGK--SWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
            I+E +  K +   W  I  T+ G  +   +  + E  E IFR++AEN  G   P  S  +
Sbjct: 4236 ILEKRDYKKEEVGWITITSTLKG--NSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGPL 4293

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
              +     P  P  P  +  V ++    SW  P+ D G+P+LGY I  ++V    W  V 
Sbjct: 4294 TAKNQFDPPDAPNTP-RVHEVTASTARLSWHEPK-DNGSPILGYWIERKEVNSKHWTRVN 4351

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEP 2052
            +  +N+L+  + +L E  TY+ R+ A N  G    SEP
Sbjct: 4352 RALINSLEVKVSNLMEGLTYIFRVCAENLAGPGPFSEP 4389



 Score =  166 bits (404), Expect = 5e-39
 Identities = 188/797 (23%), Positives = 305/797 (38%), Gaps = 58/797 (7%)

Query: 1287 PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            PP++   V  ++  ++K G+ V L  +    P P   W      +K C+    +      
Sbjct: 8051 PPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPRVTWKRGDNSLKSCEGQVITHQRHHF 8110

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             L +  V     G+Y +  EN                P P   P++ +   S+I++ W  
Sbjct: 8111 QLEMTAVTKEHTGVYTILAEN-------------ATPPGPIVNPSVTDTTYSTISLAWTA 8157

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            P N G S +I Y+VE +  +T +WI     +N+ +T   IQNL   + Y+ R  AVN V 
Sbjct: 8158 PANDGGSPVIGYLVECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVG 8217

Query: 1461 ISDASETTEYYKVIKETKIQSPTV-EKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
             S+  E    + V K+  +    V    LK  +       + L     G P+PK+TW + 
Sbjct: 8218 FSEPVEVPGKH-VAKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITWAKM 8276

Query: 1519 GKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDH---GEVETSCVVGIQQKPVI 1573
               +K  +      +                 K I FN     G    + VV +   P  
Sbjct: 8277 NTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYI-FNLESLAGMKMYTIVVKVYDTPGP 8335

Query: 1574 TISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSV 1629
             + N  +K+  K G    W       G    EV  Y    +    K ++I +    KTS 
Sbjct: 8336 PV-NLMVKETSKDGASIFWDSPLTDGGY---EVTHYIVEKRDTERKAWSIVSMNCNKTS- 8390

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--SRESVTIEW 1687
              + +L    S  + +   N  G      T        +P   +  + +  +++S TI W
Sbjct: 8391 FEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMDFKTVLVTKDSCTISW 8450

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            K PL DGG  +  Y +E    D+    K     ++++ Y  + L E  EY +RV A N  
Sbjct: 8451 KKPLSDGGSRIISYVLEVLNGDDK--YKELMRSKNMQ-YSAKDLVEGKEYTYRVKAINDS 8507

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV--- 1804
            G   A E   +     +              I  E   +           P + +K    
Sbjct: 8508 GEGAAKELTVVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDD 8567

Query: 1805 -EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863
             ++K  G+              I+    N   ++ I  RN  G     T   ++ +GK  
Sbjct: 8568 EDLKDSGRVCAESSSVNTTLL-IRDCQRNDASKYTITLRNSAGIK-ESTIFIRV-VGKPG 8624

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
             P   P  F   + T+   TLKW  P+ +GGS I NYI+E +      W   VTV  SV 
Sbjct: 8625 IPVG-PIKF--KDVTADGATLKWGAPKDDGGSDIANYILEKRDSVTNMW---VTVSSSVE 8678

Query: 1924 EHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
             +   +  + E  E IFR+ AEN  GV    +S  +  +    VP  P  P +I  +  N
Sbjct: 8679 TNSMRVTGLHEGTEYIFRVCAENKYGVGEGLKSDPIIAKHPFNVPEAPPPP-QIMNMQHN 8737

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
                +W  P   GG+P+ GY++  ++    +W       +   + ++  L+E   Y  R+
Sbjct: 8738 SAYLAWLDPRKTGGSPITGYHLEFKERNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRV 8797

Query: 2042 YARNEIGLSEPLESDEP 2058
             A N  G+ +P    +P
Sbjct: 8798 MAINLAGIGKPSAPTDP 8814



 Score =  163 bits (397), Expect = 4e-38
 Identities = 177/759 (23%), Positives = 320/759 (42%), Gaps = 68/759 (8%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENN--CGHADVEMNVTI---LDKPSPPGKPNILEIDSS 1395
            K  S  + K+      I+++  EN   CG   +   +T     D P  P  P + E+ +S
Sbjct: 4257 KGNSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGPLTAKNQFDPPDAPNTPRVHEVTAS 4316

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453
            +  + W EP++ G S I+ Y +E +E+++  W  V    I   +  + NL    +Y FR 
Sbjct: 4317 TARLSWHEPKDNG-SPILGYWIERKEVNSKHWTRVNRALINSLEVKVSNLMEGLTYIFRV 4375

Query: 1454 YAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
             A N       S+ S+ T     I      +P +    K+      +   L    G +  
Sbjct: 4376 CAENLAGPGPFSEPSDRTTAMDAILPPGPPTPWIVDTGKDFVIVAWKP-PLYNGGGDILG 4434

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY-KCIAFNDHGE-----VETSCV 1564
              V     G+K  T    +  +               Y + +A ND G       E   V
Sbjct: 4435 YHVEKVLAGEKEWTRSTEFRCKDLTFTVTGLIEGADYYIRVVAINDAGPGAPGVTEPVMV 4494

Query: 1565 VGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
               Q+ PV+   +  +K+    + G+   + AV+ G P PEV W K+  +++ D+   + 
Sbjct: 4495 KEPQESPVVEF-DASVKKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMI-VE 4552

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE---IS 1679
            T+ K S + IK+  R+   KY I  +N++GT S E  + + D P    GPV+  +   ++
Sbjct: 4553 TEGKNSSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVP----GPVVDLKTVTVT 4608

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYM 1738
            ++++T+ W  P D+GG ++  Y + + +     +    +        C IQ L    EY 
Sbjct: 4609 KKNITLTWSDPHDNGGSDIIGYDVLRKDAKMKLFRHPMET---ASCKCDIQGLLAGEEYD 4665

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            FRVIA+N  G     +  PI+ +     PS              ++ + W P   +GGSP
Sbjct: 4666 FRVIARNKYGDGAPSDLGPILAQDPKGTPSAPEKLHYTDR-GKTTIMLAWQPPRTDGGSP 4724

Query: 1799 IIDYKVE-IKQEGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTS-- 1853
            I  Y VE ++ +  +++             I+ LS N  YQFR+ A NE+G   P  +  
Sbjct: 4725 IRGYYVEKMRSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAIT 4784

Query: 1854 ----DDKITIGKTLTPPSQPRNFVVSESTSRSV----------TLKWTEPESNGGSPITN 1899
                DD++    T+    +    ++ + ++  +          +L+W + +    +P+ +
Sbjct: 4785 AKIQDDELAPVITILKFFKSNAIIIKKGSAIDIPAEVKGLPLPSLQWVKDDVVIETPVED 4844

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
             +I  +T +    T    +        I     +D+  +++ AEN  G     ++Q V  
Sbjct: 4845 KMI-METEEMDRTTLRTKI-------AIPETVRQDKGNYKLVAENCFG-----KAQHVIR 4891

Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW-MEVGK 2018
             +    P PP   +   +   +  +T W  PE +GG+ +  Y I  RD +K     EV  
Sbjct: 4892 VEILDRPLPPRNVVVSDIKADSCYLT-WDVPEDNGGSEITNYIIERRDASKKKSDFEVQT 4950

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             ++   ++ +  L+ N  Y  RI A N+ G+S+  +S++
Sbjct: 4951 TNLIDRRYGVYKLNVNGAYQFRIKAENKYGISDGCDSEK 4989



 Score =  163 bits (397), Expect = 4e-38
 Identities = 159/596 (26%), Positives = 242/596 (40%), Gaps = 43/596 (7%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +  G  + ++      P P+  W  +   +      K      S++L IK       G+Y
Sbjct: 5757 VHAGGVIRIIAYVSGQPTPDITWSRDGSALPP--EAKVETTFISSALIIKPCSRKHLGVY 5814

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVV 1417
             L  +N  G     + V +LD P P G P   E + + S  + W  PEN G S I  Y+V
Sbjct: 5815 TLTAKNAGGEKKKNVTVEVLDVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIV 5874

Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            E +E +   W SV    ++T      L +  SY FR  A N + I    ET     VI+E
Sbjct: 5875 EKREAERKAWTSVSFTASRTNAVAHGLTSGKSYFFRVAAENAIGIGPFVETAAEV-VIRE 5933

Query: 1477 T--------KIQSPTVEKPLKNITTEPNED---IELTC-IFGGVPQPKVTWYRDGK-KLK 1523
                     +++   V K L ++T +P +     E+T  I       K  + R  K KL 
Sbjct: 5934 PISIPERPEELEVHKVTKDLISVTWKPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLL 5993

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQK-----PVITISN 1577
              K TY+                 ++ IA N+ G  + S C   I  K     P I +  
Sbjct: 5994 ERKYTYDG--------LREGDTYEFRVIAVNEVGPGKPSFCTKPITCKDELEPPTIELDF 6045

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
             D K   +VG+  L+     G PPP + WY++  +++ DK         T  + + + +R
Sbjct: 6046 RD-KIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTLTTMSLGLMKAQR 6104

Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
             HS +Y +   N+ G+      + V   P  PE P + RE+   +  + W  P  DGG  
Sbjct: 6105 EHSGRYVVVVENSTGSRKGICNVTVVGVPEAPEMPTV-REVYATNALVLWNRP-RDGGKP 6162

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755
            +T Y +EK E    RW +         T + +Q L E CEY FRV+A+N +G  +  E S
Sbjct: 6163 ITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAENELGTGDPSEPS 6222

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814
            +PI+ K  +  PS             +SV + W     +G   I  Y VE K+ G  +W 
Sbjct: 6223 KPILAKDPIVCPSPPVTPEAYDK-TKDSVSLKWKLPRHDGKGRIFGYLVEYKKPGAVEWI 6281

Query: 1815 XXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
                           +  L+    Y FRI+  N  G S P    + I +   L  P
Sbjct: 6282 QANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIKVHDRLEKP 6337



 Score =  162 bits (394), Expect = 8e-38
 Identities = 117/463 (25%), Positives = 209/463 (45%), Gaps = 12/463 (2%)

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            F+   +++TVKE+ T +    ++   + S+ WY+N+  + PS+ I  +  G+    + T 
Sbjct: 1396 FVKPIKDVTVKERETAEFSVELSHENI-SVVWYKNDIRLHPSKVIHMSDHGK----IHTL 1450

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
               E+   D   +   +  K+   A +T+    + F   LQ +Y   E   V L C+ S 
Sbjct: 1451 AFKEVSIDDTSMIKVEAMDKTV-TAMLTVIEGDLYFTTKLQ-NYTAVEKDEVKLRCELSK 1508

Query: 955  TV-STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
             +   KW+ + KE++   +  II +G+            ++G   C     +T+  L ++
Sbjct: 1509 AIGDVKWFKDGKELTPSKNIAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIE 1568

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            E   + +R L   EV E + A  E EI+ +     W+  GE ++   +  + ++ G    
Sbjct: 1569 ERDIKIVRPLYSVEVTETETAKFETEISEDDVHGNWKLKGEALQQSAD-VEMKEEGTRHM 1627

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133
            L + N  +   G       +   +A++ V      ++  L++  V  G  ATFE EL+  
Sbjct: 1628 LVLYNVHMDMAGAVDFSAANARSSAQLRVKARSVGLVRPLKDVMVTAGETATFECELSYE 1687

Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
              +V WF  G +++    ++  + G+   L I D +L +AGE      + +  A L V+E
Sbjct: 1688 GIVVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTAKDFQTQAHLIVKE 1747

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
            P + FT  L E   V  ++   L   +  E  +V W++    +  T+KF L+S   KR L
Sbjct: 1748 PPVEFTKPL-EDQTVEEDSTVTLECAVSRENAEVRWFRDGQELRKTKKFDLLSLGCKRML 1806

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYE 1294
            +I  C+ +D   YTC   D K++  L V    VEF   + D E
Sbjct: 1807 VIHNCSSEDIKMYTCDTKDFKTSCYLDVTPPHVEFTKLLQDVE 1849



 Score =  161 bits (390), Expect = 3e-37
 Identities = 108/399 (27%), Positives = 179/399 (44%), Gaps = 17/399 (4%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G +  V AV+ G P P   W +  + +       +       V+ IK++ R+ S +Y+
Sbjct: 7673 RAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGNLCVLIIKDVSRTDSGEYS 7732

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            + A N++   +  + + + D P  PEGPV + +I  ++ ++ W  PL+DGG  +T Y +E
Sbjct: 7733 LVAENSSSKVTQALKIVIRDIPGPPEGPVEISDIDSDACSLSWNKPLEDGGSNITNYVVE 7792

Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            K +     W  V  V    +T C + KL    EY+FR+ A+N  G S+ ++S+ +V K  
Sbjct: 7793 KCDVSRGDW--VTAVSSVSKTSCRLGKLIPGKEYVFRIRAENRFGLSDPIQSDRMVAKFP 7850

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW---KXXXXXX 1820
               P            + + +++ W     +GGSPI  Y +E K+    +          
Sbjct: 7851 FGEP----LNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIERKERNSLFFVKANDTIVR 7906

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                    L     Y F++ A N    S P  +   +T    +  P +P    V + T  
Sbjct: 7907 TTQYPCAGLIKGLEYTFKVSAINRACQSKPSANTYFVTARTPVYTPGKPE---VLDITKN 7963

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHCIENIKEKDEIIF 1938
            SVTL WT P+++GGS I  Y +E   V G SW +  T   +V   E+ +  ++      F
Sbjct: 7964 SVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQF 8023

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
            R+ A+  V +S P+E     L     V  PP   L +RM
Sbjct: 8024 RVIAKTAVNISKPSEPTDPVLVCAENV--PPRLDLNVRM 8060



 Score =  156 bits (379), Expect = 5e-36
 Identities = 122/469 (26%), Positives = 216/469 (46%), Gaps = 19/469 (4%)

Query: 830  AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886
            A P  F+ + Q+I ++E  +I    V     +P  +IT W ++   +          DG+
Sbjct: 531  AVPLKFVKKLQDIVLQEAESIGSSAVFECQISPSTAITSWMKDGGNLREGPKYKFTADGK 590

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            + +L I +V    D+G+Y CVA N+  + +  A++ ++   V +VK L+      +G+ +
Sbjct: 591  DRKLNILDVQLS-DTGEYTCVARNAGKEITCTAKLIVEELPVKWVKELEPETTCMKGQPM 649

Query: 947  ILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
             L C+ +      W  N   +     +  I   G             D G   C V+ +E
Sbjct: 650  YLTCELNKERDVTWKRNGAVLKKKAGKVAINIIGLQHAVTIQNATEEDTGAYTCEVEGRE 709

Query: 1006 ---TSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
               T+T + V E I +++ K L+D  VK K  A  + E+  +T +  W +    I P + 
Sbjct: 710  DISTTTNVKVLEIIKDWLVKPLRDQHVKPKSKATFKGELFKDTPNWKWLKGETEITPSE- 768

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--------VELPPEIITRL 1113
            K +  K G    L I N    D  EY+  + D   TA++T+         E   EI+  L
Sbjct: 769  KMEIAKDGANVTLTINNCQPDDVSEYTIEVEDRRYTAKLTLGGAVRRRFQEREAEILKPL 828

Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
             + +V +  +A F+ E+++ D +  W   G  +  S    + ++G+K+ L + +  +D A
Sbjct: 829  ASLEVVEKEEANFDTEISEEDIIGEWKLRGQVLTRSPTCDIKLEGRKRFLTLKNVQVDQA 888

Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
            GE S +  N+  T +LTV+E  + F   L + + VP    A     +  E   V W+K  
Sbjct: 889  GEVSYQALNAVTTGMLTVKELEMGFVDPLKD-VSVPEKKQAKFECTVTKEVPKVMWFKGA 947

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             ++    K+ +I D  K  L+I  C  DD+ +YT  +L  +S+++L+VE
Sbjct: 948  EIVTPGPKYEIIDDGLKHMLVINSCEFDDEAQYTIEVLGQRSSSQLRVE 996



 Score =  155 bits (376), Expect = 1e-35
 Identities = 130/502 (25%), Positives = 201/502 (40%), Gaps = 20/502 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P P   W     +L  D+  ++ TK   + + +    R     YT++  N   + S
Sbjct: 2883 ITGYPTPVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLENDISSVS 2942

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
             EV + V   PS P+   +  E+SR  V + W+ P  DGG  +T Y IEK E     W+K
Sbjct: 2943 GEVEVNVIACPSAPKDFKVA-EVSRHHVHLMWEAPEHDGGSPVTHYQIEKREVSRKTWVK 3001

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXX 1774
            VA    D+E + +  + E  EY+F V A N  G  E A   EP+ I +   VP       
Sbjct: 3002 VASGVLDLE-HTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLK 3060

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK-XXXXXXXXXARIQKLSIN 1832
                   +S+++ W P + +GGSP+  Y V+  Q G  KW+           ++  L   
Sbjct: 3061 WRDKC-AKSIFLLWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQVSGLLEG 3119

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
              Y +R+ A N++G S P  + D I       PP    +  +    +     K   P   
Sbjct: 3120 QWYSYRVRAFNKLGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADV 3179

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLP 1951
             G P          +  ++  ++       H    I N    D   + I A N  G +  
Sbjct: 3180 KGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATA 3239

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
            T   ++ L+K    P PP A  +I  + S     +W  P  DGG+P+  Y +  R   K 
Sbjct: 3240 TIDVNI-LDK----PGPPAA-FDISEITSESCCLAWNPPRDDGGSPITNYIVESRQTDKE 3293

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071
             W+++    V    F    L+    Y+ RI A N+ G+ EP E       +P    ++ +
Sbjct: 3294 EWIKL-SATVKHTTFKACKLTGMKEYIFRISAENQFGIGEPAEH------VPIVAKYSFD 3346

Query: 2072 EPGEQTEVXXXXXXXXXXXXXW 2093
             PG  T V             W
Sbjct: 3347 PPGSPTRVTPSDITKDAVTLTW 3368



 Score =  153 bits (371), Expect = 5e-35
 Identities = 103/383 (26%), Positives = 160/383 (41%), Gaps = 10/383 (2%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
            I   D K     G  +++    +  P  E  W+     L      NI T    +  R+K 
Sbjct: 2468 IKTTDQKLVTDAGKPFIMRVPYDAYPRAEAEWFFEDTSLPVQ---NIDTSVDKTEYRLKS 2524

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
              +    +Y +  SN  G +   + L V D P   +   ++     E V++ W+ P  DG
Sbjct: 2525 PSKEDQGQYKVVISNKHGAAEAFIVLDVIDVPGSVKNLRVLDTADGE-VSLAWEEPESDG 2583

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
            G ++  Y +E+ +     W    D   D   YC+  L+++  Y+FRV A+N VG   A+ 
Sbjct: 2584 GSKIIAYVVERRDVKRKTWALATD-RADTPEYCVTGLHKDSAYLFRVCARNRVGSGPAVV 2642

Query: 1755 SEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812
            +E  V  K   DVP           ++     I+W P + +GGS I  Y +E++     K
Sbjct: 2643 TEDAVQAKNKFDVPDAPEDVAVET-VNKFGATISWKPPKFDGGSEITAYVIELRDRTSVK 2701

Query: 1813 WKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
            W+           A +  +  N  Y FR+ A N  G   P  + + + I   +  PS P 
Sbjct: 2702 WEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIERPSPPL 2761

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
            N   S+    +VTL W  P SNGGS IT YIIE        W +          + +  +
Sbjct: 2762 NLNFSDQIKTAVTLTWETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLSYRVSGL 2821

Query: 1931 KEKDEIIFRISAENTVGVSLPTE 1953
            K     ++R+ AEN  GVS P +
Sbjct: 2822 KPGQNYLYRVCAENAAGVSDPVQ 2844



 Score =  151 bits (366), Expect = 2e-34
 Identities = 166/744 (22%), Positives = 288/744 (38%), Gaps = 47/744 (6%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTILD---KPSPPGKPNILEIDSSSI 1397
            S T+  V      I+++R EN  G    +     V I+D   +PSPP   N  +   +++
Sbjct: 2714 SATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIERPSPPLNLNFSDQIKTAV 2773

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYA 1455
             + W+ P + G S I  Y++E  E  T +W+  + +        +  LK   +Y +R  A
Sbjct: 2774 TLTWETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLSYRVSGLKPGQNYLYRVCA 2833

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVE-----KPLKNITTEPNEDIELTCIFGGVPQ 1510
             N   +SD  +  +   ++ +     PT +     K L+ I  +P   + +     G P 
Sbjct: 2834 ENAAGVSDPVQ--QLGPLLADDPHVGPTFDLSGFRKGLEVIVPQP---LTIRVPITGYPT 2888

Query: 1511 PKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            P   W    K+L    + +  T                   Y     ND   V     V 
Sbjct: 2889 PVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLENDISSVSGEVEVN 2948

Query: 1567 IQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTK 1624
            +   P      +  +  +H V   W       G P   V  Y+   +  + K +  + + 
Sbjct: 2949 VIACPSAPKDFKVAEVSRHHVHLMWEAPEHDGGSP---VTHYQIEKREVSRKTWVKVASG 3005

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIM--REIS 1679
                   + ++  +    +++ A N  G      ++  + +    + P+ P  +  R+  
Sbjct: 3006 VLDLEHTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLKWRDKC 3065

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
             +S+ + W+PP  DGG  +  Y ++K +   ++W    D   +++   +  L E   Y +
Sbjct: 3066 AKSIFLLWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQ-VSGLLEGQWYSY 3124

Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG-S 1797
            RV A N +G S  +  ++ I    A + P           +   +      P++  G  +
Sbjct: 3125 RVRAFNKLGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADVKGKPA 3184

Query: 1798 PIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            P + + K + + +   +             I   +   T  + I A N  G +   T D 
Sbjct: 3185 PRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATA-TIDV 3243

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
             I     L  P  P  F +SE TS S  L W  P  +GGSPITNYI+E +    + W K+
Sbjct: 3244 NI-----LDKPGPPAAFDISEITSESCCLAWNPPRDDGGSPITNYIVESRQTDKEEWIKL 3298

Query: 1916 -VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
              TV  +  + C   +    E IFRISAEN  G+  P E   +  +     P  PT    
Sbjct: 3299 SATVKHTTFKAC--KLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSFDPPGSPTRVTP 3356

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
              +    + +T W  P+ DGG+P+ GY +   D     W+   K+ V    F ++ L   
Sbjct: 3357 SDITKDAVTLT-WFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKDTSFRVKGLRTK 3415

Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058
              Y  R+ A N  G  +     +P
Sbjct: 3416 KKYRFRVLAENLAGPGKASSETDP 3439



 Score =  142 bits (345), Expect = 7e-32
 Identities = 92/302 (30%), Positives = 141/302 (46%), Gaps = 10/302 (3%)

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK----XXX 1817
            T LD+P           +  + + I W   + +GG+PI +Y VE K   K W+       
Sbjct: 6600 TVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVKKPWEPWSVVSS 6659

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL-TPPSQPRNFVVSE 1876
                  A++ +L     Y  R+ A N+IG S    S    TI K +  PP  P   V S+
Sbjct: 6660 SGTNTKAKVSRLEKGREYVVRVRAENKIGISTGLESPP--TIAKHMFNPPGPPGLPVCSD 6717

Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936
             T  +VT++WT P+ +GGSPI+ Y+IE + + GK W ++         + +  + E +  
Sbjct: 6718 ITENAVTVEWTLPDYDGGSPISGYVIERREMTGK-WIRVNKTPVLDLRYRVSGLFEGNSY 6776

Query: 1937 IFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
             FR+ AEN  G+S P+  S  V+  +  T P PP  P ++R    +     W  P  DGG
Sbjct: 6777 EFRVFAENIAGISDPSLASDPVKAARAITRPGPPGNP-KLRDWSKSYADICWTKPTRDGG 6835

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            +P+LGY +  +      W  + K  +    + +  L E   Y  RI A N++G SEP E 
Sbjct: 6836 SPVLGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRIRAANKVGESEPREL 6895

Query: 2056 DE 2057
             E
Sbjct: 6896 AE 6897



 Score =  139 bits (337), Expect = 7e-31
 Identities = 151/686 (22%), Positives = 283/686 (41%), Gaps = 46/686 (6%)

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            EF++ ++D  VKE++ A   VE++ E   VVW ++   + P K  +     G I  L  +
Sbjct: 1395 EFVKPIKDVTVKERETAEFSVELSHENISVVWYKNDIRLHPSKVIH-MSDHGKIHTLAFK 1453

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
              S+ D         D++ TA +TV+E      T+LQN    + ++     EL+K    V
Sbjct: 1454 EVSIDDTSMIKVEAMDKTVTAMLTVIEGDLYFTTKLQNYTAVEKDEVKLRCELSKAIGDV 1513

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            +WFKDG E+  S +I +  DGKK+ L +   +  + GEY+C+ G+ K TA L +EE  I 
Sbjct: 1514 KWFKDGKELTPSKNIAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIEERDIK 1573

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
                L    +    T  + T EI ++ +   W  K   ++ +    +  +  +  L++  
Sbjct: 1574 IVRPLYSVEVTETETAKFET-EISEDDVHGNWKLKGEALQQSADVEMKEEGTRHMLVLYN 1632

Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
               D          +A+S+ +L+V+       +V   ++  +  G   T   +  ++   
Sbjct: 1633 VHMDMAGAVDFSAANARSSAQLRVKARSV--GLVRPLKDVMVTAGETATFECEL-SYEGI 1689

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              EW +  + ++  +  K  +  ++ +LTI+ V  ++AG  KL  ++    A + +    
Sbjct: 1690 VVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTAKDFQTQAHLIVKEPP 1749

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKT 1436
            ++  + P +   +E DS+    C    EN      + +  + QE+  T+   + ++  K 
Sbjct: 1750 VEF-TKPLEDQTVEEDSTVTLECAVSRENAE----VRWFRDGQELRKTKKFDLLSLGCKR 1804

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               I N    SS   + Y  +  D       T  Y  +    ++     K L+++     
Sbjct: 1805 MLVIHNC---SSEDIKMYTCDTKDFK-----TSCYLDVTPPHVE---FTKLLQDVEVRER 1853

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            E  +  C        KV W++DG +++  K  YE                 +K   F+D 
Sbjct: 1854 EAAKFECEVSR-ESAKVRWFKDGSEIRKGK-KYE-----ITASGVQRTLIIHKS-GFDDE 1905

Query: 1557 GEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI-----PPPEVIWYKNG 1610
             E E       +   ++T+  E  K  K+    E + T  ++ I        EV WY+  
Sbjct: 1906 AEYECDARTS-KTSGLLTVIEEAPKFTKNLSNVEGMETDSVKMICEVSKASAEVTWYRGE 1964

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV----EVTLKVYDKP 1666
             +L     Y      +  ++ IK L+   + +YT   S    TS+V    E+  +   +P
Sbjct: 1965 EELPEVGRYEQIMDGRKRILIIKGLRMEDAGQYTCRLSPNIKTSAVLQLNELAAEFISRP 2024

Query: 1667 SKPE-----GPVIMREISRESVTIEW 1687
               E            +S+E+  ++W
Sbjct: 2025 QNQEVVEGQAAEFTCSVSKETYEVKW 2050



 Score =  139 bits (336), Expect = 9e-31
 Identities = 123/574 (21%), Positives = 227/574 (39%), Gaps = 23/574 (4%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547
            LK+ T    ED + TC      +  V WY++G++++     +  R               
Sbjct: 2295 LKDQTVTEFEDADFTCKLNK-EKASVKWYKNGREIREGPRYHMQREGKVCRLIIKECRPD 2353

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
             +C       E  T   + +++ PV  I       +    D  +V  V       EV W 
Sbjct: 2354 DECEYACGMDERRTRARLFVEETPVEIIRPPQDMLEPPASD--IVFEVELNKDRVEVKWM 2411

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +N   +    +Y + ++ K   +++ E++     +Y I A +    + +E+      K +
Sbjct: 2412 RNNMIIVQGDKYQMISEGKIHRLQVCEIRPRDQGEYRIVAKDKDARAKLELAAVPKIKTT 2471

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
              +   ++ +  +  +    + P D       ++  E    D +  ++  D   D   Y 
Sbjct: 2472 DQK---LVTDAGKPFIM---RVPYDAYPRAEAEWFFE----DTSLPVQNIDTSVDKTEYR 2521

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
            ++  ++  +  ++V+  N  G +EA      ++   +DVP            D E V + 
Sbjct: 2522 LKSPSKEDQGQYKVVISNKHGAAEAF-----IVLDVIDVPGSVKNLRVLDTADGE-VSLA 2575

Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEI 1845
            W   E +GGS II Y VE +   +K W             +  L  ++ Y FR+ ARN +
Sbjct: 2576 WEEPESDGGSKIIAYVVERRDVKRKTWALATDRADTPEYCVTGLHKDSAYLFRVCARNRV 2635

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
            G+     ++D +        P  P +  V        T+ W  P+ +GGS IT Y+IE +
Sbjct: 2636 GSGPAVVTEDAVQAKNKFDVPDAPEDVAVETVNKFGATISWKPPKFDGGSEITAYVIELR 2695

Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHAT 1964
                  W   +          + ++ E  E IFR+ AEN  GV  P+ + + V++     
Sbjct: 2696 DRTSVKWEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIE 2755

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
             PSPP        + + + +T W TP  +GG+ + GY I   +     W+         L
Sbjct: 2756 RPSPPLNLNFSDQIKTAVTLT-WETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDL 2814

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             + +  L     Y+ R+ A N  G+S+P++   P
Sbjct: 2815 SYRVSGLKPGQNYLYRVCAENAAGVSDPVQQLGP 2848



 Score =  138 bits (335), Expect = 1e-30
 Identities = 212/935 (22%), Positives = 372/935 (39%), Gaps = 93/935 (9%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK 1250
            E P + F   + + +++ A     L   +      +V W K +  I D ++  + ++ K 
Sbjct: 4499 ESPVVEFDASVKKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEI-DKDRMIVETEGKN 4557

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
             +L I+K T  D  +Y     ++  T   + +V++++ P  +VD +     K+  ++TL 
Sbjct: 4558 SSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVPGPVVDLKTVTVTKK--NITL- 4614

Query: 1309 VDYQAFPQPNDEW---IVNSKIIKK---CKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
                 +  P+D     I+   +++K    K  +  +++ S    I+ +   +   +++  
Sbjct: 4615 ----TWSDPHDNGGSDIIGYDVLRKDAKMKLFRHPMETASCKCDIQGLLAGEEYDFRVIA 4670

Query: 1363 ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             N  G         IL +     PS P K +  +   ++I + W  P   G S I  Y V
Sbjct: 4671 RNKYGDGAPSDLGPILAQDPKGTPSAPEKLHYTDRGKTTIMLAWQPPRTDGGSPIRGYYV 4730

Query: 1418 EYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            E    D+ E+   + K  T+   +I+NL  N  Y+FR  AVNEV   + S+     K+  
Sbjct: 4731 EKMRSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAITA-KIQD 4789

Query: 1476 ETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE 1530
            +      T+ K  K+  I  +    I++     G+P P + W +D   ++T    K   E
Sbjct: 4790 DELAPVITILKFFKSNAIIIKKGSAIDIPAEVKGLPLPSLQWVKDDVVIETPVEDKMIME 4849

Query: 1531 N--------RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
                     R               YK +A N  G+ +    V I  +P+       +  
Sbjct: 4850 TEEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFGKAQHVIRVEILDRPLPP--RNVVVS 4907

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWY----KNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
              K    +L   V E     E+  Y    ++ +K ++D E   TT        + +L  +
Sbjct: 4908 DIKADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQ-TTNLIDRRYGVYKLNVN 4966

Query: 1639 HSSKYTIEASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             + ++ I+A N  G S    S +V L   +  P  P  P I+   +  ++T+ W PPLD+
Sbjct: 4967 GAYQFRIKAENKYGISDGCDSEKVQLSDPFGLPGPPRNPKIIAATAT-TMTLTWDPPLDN 5025

Query: 1694 GGLELTKYAIEKHEPDNNRWIKV--ADVDRDVET---YCIQKLNENCEYMFRVIAQNPVG 1748
            GG  +  Y +EK E     W +V  A V +       Y + KL E  EY FR+ A N  G
Sbjct: 5026 GGSTIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAG 5085

Query: 1749 FSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
                 E SE        + PS            N S+ ++W P +K+GGSP+  Y +E+ 
Sbjct: 5086 VGPPSEASECRFAVDPCNPPSSPGAPEVKDKTKN-SITLSWSPPDKDGGSPVKGYIIEVH 5144

Query: 1808 QEG-KKWKXXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT---- 1858
            +EG   W+               +  L      +FRIYA N  G S P  + + +T    
Sbjct: 5145 EEGCPDWRRVNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAEILTQDIL 5204

Query: 1859 IGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESN-----GGSPITNYIIEFKTVKGKS 1911
            I  T+T      + +   ++ST R        P         G+  T    +   +   S
Sbjct: 5205 IEPTVTLDVSAHDLLNCRADSTIRIPATITGRPLPKVTWTFDGTAETEKKNDLHILPVDS 5264

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRI-SAENTVGVSLPTESQS------VRLEKHA- 1963
              +  ++G  ++ +  +++     + F+I S++ T  V++P    +      +  E  A 
Sbjct: 5265 EVRPFSLGELIYHNAFKSLTLFPHVSFQIHSSDTTSVVTIPISKLAHSGRYIINAESPAG 5324

Query: 1964 --------TVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
                    TV   P  P ++++  V       +W  P+ DGG  +  Y I  + V    W
Sbjct: 5325 HKVVKVRVTVLDLPGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIEKKTVHGKAW 5384

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             +V           + DL+    Y+ RI A N  G
Sbjct: 5385 TKVNPA-CAAQSLVVPDLNNGQEYLFRIRAENRFG 5418



 Score =  138 bits (335), Expect = 1e-30
 Identities = 126/512 (24%), Positives = 197/512 (38%), Gaps = 31/512 (6%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            LD    PGKP ++ I  S++ + W EP+  G   +  Y++E +++ +  W+   N+   +
Sbjct: 8818 LDPIDVPGKPEVISITKSTVTLQWIEPQFDGGHRLTGYIIEKRDLPSKIWMKANNVNVLE 8877

Query: 1438 T--SIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTV---EKPLKNI 1491
               ++ +L+    Y FR  A N    IS ASE T+   +I   +  +PT+    +  + +
Sbjct: 8878 PAFTVMDLQEGCKYEFRIRAKNAAGAISPASEQTD--TIICRDEYAAPTIVIDAQVKEGL 8935

Query: 1492 TTEPNEDIELTCI-FGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXX 1546
            T    + I +T     G P P   W + GK  K +      T                  
Sbjct: 8936 TVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRKDTG 8995

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
             Y   A N  G  E +  V +   P     I    I  + KV   W       G P    
Sbjct: 8996 EYVITASNPFGVKEETVKVTVLDVPDSPGPIECSGISSE-KVALSWTAPTENGGSP---- 9050

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--TIEASNTAGTS--SVEVTL 1660
            I Y    K E  +      +EK         K    ++Y   + A N  G S  S    +
Sbjct: 9051 IKYYTLEKRETSRLLWTVLEEKVVDCHYVAYKLIQGNEYFFRVSAVNQYGASEPSHSEAV 9110

Query: 1661 KVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
            K+ D+   P  P  P +  ++   S T+ W+ P DDGG ++  Y +EK E    RW++ +
Sbjct: 9111 KMVDRFGPPGPPSKPEV-EKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRAS 9169

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
                    + +  L E+ EY FRV A+N  GF E  E    V   A+  P          
Sbjct: 9170 KKSIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNPRIT 9229

Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTT 1834
                 +  + W     NGG  I  Y +E K+EG + W              + +L     
Sbjct: 9230 DTTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAK 9289

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
            Y FRI A N  G   P  + + + I +  + P
Sbjct: 9290 YHFRISAVNSKGAGEPAETSELVEIIERASEP 9321



 Score =  136 bits (328), Expect = 8e-30
 Identities = 183/847 (21%), Positives = 315/847 (37%), Gaps = 63/847 (7%)

Query: 524  GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            GS+  FECQ+   P   IT W +    ++    ++   D  +   L I +V   D G +T
Sbjct: 552  GSSAVFECQIS--PSTAITSWMKDGGNLREGPKYKFTADGKD-RKLNILDVQLSDTGEYT 608

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            CVA+NA    + T +LIVE        E+ V              + E  P T   K + 
Sbjct: 609  CVARNAGKEITCTAKLIVE--------ELPVKW------------VKELEPETTCMKGQP 648

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYCSVLKITNVK 701
             Y        L C L    E D+ W   G  +      +++ I    H     + I N  
Sbjct: 649  MY--------LTCEL--NKERDVTWKRNGAVLKKKAGKVAINIIGLQH----AVTIQNAT 694

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            +   G YT      EG   +     +K  E     +++PL+   V+         ++   
Sbjct: 695  EEDTGAYTCEV---EGREDISTTTNVKVLEIIKDWLVKPLRDQHVKPKSKATFKGELF-K 750

Query: 762  PRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
              P   W K      P + +    DG   ++TI    +  D   YT++ E+    A+ + 
Sbjct: 751  DTPNWKWLKGETEITPSEKMEIAKDGANVTLTI-NNCQPDDVSEYTIEVEDRRYTAKLTL 809

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
               V    +E       +     + V EK        ++   +    W    ++++ S T
Sbjct: 810  GGAVRRRFQEREAE--ILKPLASLEVVEKEEANFDTEISEEDIIG-EWKLRGQVLTRSPT 866

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                 +G    L + NV  +  +G+    A N+         +T+   ++ FV  L K  
Sbjct: 867  CDIKLEGRKRFLTLKNVQVD-QAGEVSYQALNAVTT----GMLTVKELEMGFVDPL-KDV 920

Query: 939  ETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
               E K    EC  T       W+   + ++     EII +G             D    
Sbjct: 921  SVPEKKQAKFECTVTKEVPKVMWFKGAEIVTPGPKYEIIDDGLKHMLVINSCEFDDEAQY 980

Query: 998  KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
               V  Q +S+ L V+     F++ LQD  VKE   A  E+E+  +   V+W R+ E+  
Sbjct: 981  TIEVLGQRSSSQLRVEGIRLNFVQPLQDQTVKEGKTAHFELELTHDNVPVLWYRN-EVKL 1039

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
                       G   +L +R  S+ D  +     +     A++TVVE     + +LQ+  
Sbjct: 1040 HVSRTVLMHVEGKKHRLEMRTVSLDDTCQIKAEAKGIYSVAQLTVVEGDAVFVVKLQDFA 1099

Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
              + ++     EL+K D  V W+    EI  S  + L  +G  + L +   +    G Y+
Sbjct: 1100 ATEKDELLLSCELSK-DVPVVWYHSEKEITASKTVVLKSEGTCRSLLLKRVEQSSKGTYT 1158

Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237
            C+ G  K +A++ V+   +     L    L    T A   VEI ++ +   W     V+ 
Sbjct: 1159 CDCGTDKTSAVVDVQARDVKIVRPLYGVELFDGET-ARFEVEISEDDVRGQWKLNGDVLS 1217

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297
             +    +I D  K TLI+  C      E      +AK + KLKV+  E P   +    + 
Sbjct: 1218 RSPDVDIIEDGSKHTLILYNCRVAMAGEVAYTAANAKCSAKLKVK--ELPLNFLTSLNDV 1275

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
            ++    +    V+    P  +  W+  S+ ++  +  +   +  +  L I+     D   
Sbjct: 1276 QVYEKDEARFEVELSR-PPKSFRWLKGSQELQSDEKYELIQEGHTYVLLIRSAIYEDEAK 1334

Query: 1358 YKLRLEN 1364
            Y    E+
Sbjct: 1335 YMFEAED 1341



 Score =  135 bits (326), Expect = 1e-29
 Identities = 126/504 (25%), Positives = 213/504 (42%), Gaps = 31/504 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMIVRQGE 750
            +K+   K+F   T   V V++ GE S   +  + TG     ++    ++PLK + V + +
Sbjct: 869  IKLEGRKRFL--TLKNVQVDQAGEVSYQALNAVTTGMLTVKELEMGFVDPLKDVSVPEKK 926

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKA 807
                   V     P + W K  + V   P      DG  H + ++   +  DE  YT+  
Sbjct: 927  QAKFECTVTKEV-PKVMWFKGAEIVTPGPKYEIIDDGLKHML-VINSCEFDDEAQYTI-- 982

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
               E + + S+     E    N     F+   Q+ TVKE  T      +T + VP + WY
Sbjct: 983  ---EVLGQRSSSQLRVEGIRLN-----FVQPLQDQTVKEGKTAHFELELTHDNVP-VLWY 1033

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            RN   +  S T+  + +G+   L +  V     S D  C     A      A++T+    
Sbjct: 1034 RNEVKLHVSRTVLMHVEGKKHRLEMRTV-----SLDDTCQIKAEAKGIYSVAQLTVVEGD 1088

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
              FV  LQ    TE+ + ++L C+ S  V   WYH++KEI+      +  EG        
Sbjct: 1089 AVFVVKLQDFAATEKDE-LLLSCELSKDVPVVWYHSEKEITASKTVVLKSEGTCRSLLLK 1147

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                   G   C     +TS ++ V+    + +R L   E+ + + A  EVEI+ +    
Sbjct: 1148 RVEQSSKGTYTCDCGTDKTSAVVDVQARDVKIVRPLYGVELFDGETARFEVEISEDDVRG 1207

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W+ +G+++  +    D  + G    L + N  V   GE +    +  C+A++ V ELP 
Sbjct: 1208 QWKLNGDVLS-RSPDVDIIEDGSKHTLILYNCRVAMAGEVAYTAANAKCSAKLKVKELPL 1266

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
              +T L + +V + ++A FE+EL++     RW K   E+Q     +L  +G    L I  
Sbjct: 1267 NFLTSLNDVQVYEKDEARFEVELSRPPKSFRWLKGSQELQSDEKYELIQEGHTYVLLIRS 1326

Query: 1168 CDLDDAGEYSCEVGNSK--CTAIL 1189
               +D  +Y  E  + +  C  IL
Sbjct: 1327 AIYEDEAKYMFEAEDKRTACKLIL 1350



 Score =  132 bits (320), Expect = 8e-29
 Identities = 182/828 (21%), Positives = 319/828 (38%), Gaps = 53/828 (6%)

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            ++ FVK + K    +E +T     + SH  +S  WY N   +       +   G+     
Sbjct: 1393 RLEFVKPI-KDVTVKERETAEFSVELSHENISVVWYKNDIRLHPSKVIHMSDHGKIHTLA 1451

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D  +IK    D+  + ML V E    F  KLQ++   EKD   L  E++    
Sbjct: 1452 FKEVSIDDTSMIKVEAMDKTVTAMLTVIEGDLYFTTKLQNYTAVEKDEVKLRCELSKAIG 1511

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            DV W +DG+ + P KN       G  R L +R     + GEY+C    +  TA++ + E 
Sbjct: 1512 DVKWFKDGKELTPSKN-IAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIEER 1570

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
              +I+  L + +V +   A FE E+++ D    W   G  +Q S  +++  +G +  L +
Sbjct: 1571 DIKIVRPLYSVEVTETETAKFETEISEDDVHGNWKLKGEALQQSADVEMKEEGTRHMLVL 1630

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
            Y+  +D AG       N++ +A L V+  S+     L + ++V A   A    E+  E +
Sbjct: 1631 YNVHMDMAGAVDFSAANARSSAQLRVKARSVGLVRPLKD-VMVTAGETATFECELSYEGI 1689

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVV 1284
             V W+     +E  E+       +   L IR     +  E   V L AK   T+  + V 
Sbjct: 1690 VVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGE---VKLTAKDFQTQAHLIVK 1746

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKS 1342
            E P +      +  ++  S VTL     A  + N E  W  + + ++K K          
Sbjct: 1747 EPPVEFTKPLEDQTVEEDSTVTLEC---AVSRENAEVRWFRDGQELRKTKKFDLLSLGCK 1803

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSPPGKPNILEIDSSSINICW 1401
              L I    + D  +Y       C   D + +  + +  P       + +++        
Sbjct: 1804 RMLVIHNCSSEDIKMY------TCDTKDFKTSCYLDVTPPHVEFTKLLQDVEVREREAAK 1857

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
             E E +  S  + +  +  EI        K    T + +Q         F   A  E D 
Sbjct: 1858 FECEVSRESAKVRWFKDGSEIR-----KGKKYEITASGVQRTLIIHKSGFDDEAEYECD- 1911

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
            +  S+T+    VI+E    +P   K L N+     + +++ C        +VTWYR  ++
Sbjct: 1912 ARTSKTSGLLTVIEE----APKFTKNLSNVEGMETDSVKMICEVSKA-SAEVTWYRGEEE 1966

Query: 1522 LKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            L      YE      +               Y C        ++TS V+ + +     IS
Sbjct: 1967 LPEV-GRYEQIMDGRKRILIIKGLRMEDAGQYTC---RLSPNIKTSAVLQLNELAAEFIS 2022

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
                 Q+   G     T  +      EV W++   +LEN  ++ I ++ K  V+ +K  +
Sbjct: 2023 RPQ-NQEVVEGQAAEFTCSVSK-ETYEVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCE 2080

Query: 1637 RSHSSKY-----TIEAS-NTAGTSSVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKP 1689
                  Y      I+AS +   T  + V   + D   K    ++   E + E    +W  
Sbjct: 2081 LKDEGGYVAHIGAIKASADLLVTEKLRVITPIKDTEVKEGSEIVFNCEANAEGAKAKWLK 2140

Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDR-DVETYCIQKLNENCE 1736
              ++   E +KY + +   DN   +++ D  + D  +Y +   N+  E
Sbjct: 2141 N-EETIFETSKYMMAQR--DNVFSLRIRDAQKTDEASYTVSLTNQRGE 2185



 Score =  131 bits (317), Expect = 2e-28
 Identities = 241/1104 (21%), Positives = 421/1104 (38%), Gaps = 84/1104 (7%)

Query: 1004 QETSTMLVVKETIPEF----IRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKP 1058
            + T  +LV  E +P      +R  +  +VK     ILE E+  +    V W+R    +K 
Sbjct: 8038 EPTDPVLVCAENVPPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPRVTWKRGDNSLKS 8097

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEIITRLQN 1115
             + +    +R H +      T  H  G Y+ +  + +    +   +V +     I+    
Sbjct: 8098 CEGQVITHQRHHFQLEMTAVTKEHT-GVYTILAENATPPGPIVNPSVTDTTYSTISLAWT 8156

Query: 1116 QKVNKGNKAT--FEIELTKGDALVRWFKDG--SEIQFSNH-IQLTIDGKKQKLKIYDCDL 1170
               N G      + +E  + +    W +      +Q +++ IQ  ID  + + +I   + 
Sbjct: 8157 APANDGGSPVIGYLVECKRANT-ADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNR 8215

Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTW 1229
                E     G      I+   E  ++  L+  E + + A     L   I       +TW
Sbjct: 8216 VGFSEPVEVPGKHVAKDIIVAPEAVLSAELK--EGLELNAGATMRLEATIKGRPRPKITW 8273

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP 1287
             K  + I+D +   + S      +++      D  +Y   L  L       + V+V + P
Sbjct: 8274 AKMNTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYIFNLESLAGMKMYTIVVKVYDTP 8333

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP--SIDSKSASL 1345
               V+   +   K G+ +     +   P  +  + V   I++K    +   SI S + + 
Sbjct: 8334 GPPVNLMVKETSKDGASI-----FWDSPLTDGGYEVTHYIVEKRDTERKAWSIVSMNCNK 8388

Query: 1346 TIKKVENTDAG-IYKLRLE--NNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
            T  +V + +AG  Y  R+   N  G   + +   +V   ++P        + +   S  I
Sbjct: 8389 TSFEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMDFKTVLVTKDSCTI 8448

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
             W +P + G S II YV+E    D  ++  +      Q S ++L     Y +R  A+N+ 
Sbjct: 8449 SWKKPLSDGGSRIISYVLEVLNGD-DKYKELMRSKNMQYSAKDLVEGKEYTYRVKAINDS 8507

Query: 1460 DISDASETTEYYKVIKETKIQSPTVE-KPLKNI--TTEPNEDIELTCIFGGVPQPKVTWY 1516
                A E T    V+ + +I  P  + + L N+    +    + L     G P PKV+W 
Sbjct: 8508 GEGAAKELT----VVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWK 8563

Query: 1517 R-DGKKLK-TAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            + D + LK + +   E+                   Y     N  G  E++  + +  KP
Sbjct: 8564 KGDDEDLKDSGRVCAESSSVNTTLLIRDCQRNDASKYTITLRNSAGIKESTIFIRVVGKP 8623

Query: 1572 VITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
             I +    IK K    D    +W       G      I  K  +    +    +++  +T
Sbjct: 8624 GIPVG--PIKFKDVTADGATLKWGAPKDDGGSDIANYILEKRDS--VTNMWVTVSSSVET 8679

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRES 1682
            + +R+  L       + + A N  G      S   +    ++ P  P  P IM  +   S
Sbjct: 8680 NSMRVTGLHEGTEYIFRVCAENKYGVGEGLKSDPIIAKHPFNVPEAPPPPQIM-NMQHNS 8738

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
              + W  P   GG  +T Y +E  E ++  W + +     ++   +  L E  EY FRV+
Sbjct: 8739 AYLAWLDPRKTGGSPITGYHLEFKERNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRVM 8798

Query: 1743 AQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
            A N  G  + +  ++P V    +DVP           I   +V + W   + +GG  +  
Sbjct: 8799 AINLAGIGKPSAPTDPRVALDPIDVPG----KPEVISITKSTVTLQWIEPQFDGGHRLTG 8854

Query: 1802 YKVEIKQ-EGKKW-KXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSD-DKI 1857
            Y +E +    K W K         A  +  L     Y+FRI A+N  G   P +   D I
Sbjct: 8855 YIIEKRDLPSKIWMKANNVNVLEPAFTVMDLQEGCKYEFRIRAKNAAGAISPASEQTDTI 8914

Query: 1858 TIGKTLTPPSQPRNFVVSES-TSRS-VTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTK 1914
                    P+   +  V E  T R+  T+  T     G  +P + +    K  K     +
Sbjct: 8915 ICRDEYAAPTIVIDAQVKEGLTVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQ 8974

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            I T   S     I+    KD   + I+A N  GV   T   +V       VP  P  P+E
Sbjct: 8975 IETTPTS-STLSIKYATRKDTGEYVITASNPFGVKEETVKVTV-----LDVPDSP-GPIE 9027

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW--MEVGKVDVNTLKFNIRDLS 2032
               + S  V  SW  P  +GG+P+  Y +  R+ ++ +W  +E   VD + + +    L 
Sbjct: 9028 CSGISSEKVALSWTAPTENGGSPIKYYTLEKRETSRLLWTVLEEKVVDCHYVAYK---LI 9084

Query: 2033 ENHTYMIRIYARNEIGLSEPLESD 2056
            + + Y  R+ A N+ G SEP  S+
Sbjct: 9085 QGNEYFFRVSAVNQYGASEPSHSE 9108



 Score =  131 bits (316), Expect = 2e-28
 Identities = 93/291 (31%), Positives = 133/291 (45%), Gaps = 14/291 (4%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR----IQKLSINTT 1834
            I  +S Y+TW   E NGGS I +Y +E +   KK                 + KL++N  
Sbjct: 4909 IKADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQTTNLIDRRYGVYKLNVNGA 4968

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            YQFRI A N+ G S    S+ K+ +      P  PRN  +  +T+ ++TL W  P  NGG
Sbjct: 4969 YQFRIKAENKYGISDGCDSE-KVQLSDPFGLPGPPRNPKIIAATATTMTLTWDPPLDNGG 5027

Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS 1949
            S I  Y +E +      W ++    VT       ++ +  + E  E  FRI+A N  GV 
Sbjct: 5028 STIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAGVG 5087

Query: 1950 LPTESQSVRLEKH-ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
             P+E+   R        PS P AP E++    N +  SW  P+ DGG+P+ GY I + + 
Sbjct: 5088 PPSEASECRFAVDPCNPPSSPGAP-EVKDKTKNSITLSWSPPDKDGGSPVKGYIIEVHEE 5146

Query: 2009 TKTMWMEVGKVDV--NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
                W  V   D    + +  + DL E      RIYA N  G SEP  + E
Sbjct: 5147 GCPDWRRVNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAE 5197



 Score =  125 bits (302), Expect = 1e-26
 Identities = 174/872 (19%), Positives = 337/872 (38%), Gaps = 63/872 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+K        E   + + C  V+    ++ W ++GEE +P+       E  M     
Sbjct: 1928 PKFTKNLSNVEGMETDSVKMICE-VSKASAEVTW-YRGEEELPEVG---RYEQIMDGRKR 1982

Query: 694  VLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +L I  ++    G YT  ++ N +  A L +       E     +  P    +V +G++ 
Sbjct: 1983 ILIIKGLRMEDAGQYTCRLSPNIKTSAVLQL------NELAAEFISRPQNQEVV-EGQAA 2035

Query: 753  ILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
              +  V       + W + +K ++        S+G    +T+ K  ++KDEG Y      
Sbjct: 2036 EFTCSV-SKETYEVKWFRGDKELENGDKFVIVSEGKRRVLTV-KNCELKDEGGYVAHI-- 2091

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G  + SA + V E           I   ++  VKE   I            +  W +N
Sbjct: 2092 --GAIKASADLLVTEKLR-------VITPIKDTEVKEGSEIVFNCEANAEGAKA-KWLKN 2141

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH-GARVTIDVEKV 928
             E I  +             L I +   + D   Y    +N  G+ +   A   +  EK 
Sbjct: 2142 EETIFETSKYMMAQRDNVFSLRIRDAQ-KTDEASYTVSLTNQRGEQATCTASAKVAEEKH 2200

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             F++ ++   ET+E KT+   C+ +   V  KW    +E++         +G        
Sbjct: 2201 RFLQPIE-DIETQEKKTISFVCKVNRPEVMVKWTKAGQEVALSKRIVYRADGLKHTLTIK 2259

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D G    +V +   +  L+V E   +F   L+D  V E + A    ++N E A V
Sbjct: 2260 DCVMEDEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADFTCKLNKEKASV 2319

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W ++G  I+ +  +Y  ++ G + +L I+     DE EY+C + +    A + V E P 
Sbjct: 2320 KWYKNGREIR-EGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTRARLFVEETPV 2378

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
            EII   Q+      +   FE+EL K    V+W ++   I   +  Q+  +GK  +L++ +
Sbjct: 2379 EIIRPPQDMLEPPASDIVFEVELNKDRVEVKWMRNNMIIVQGDKYQMISEGKIHRLQVCE 2438

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPD-ETL 1225
                D GEY     +    A L +   P I  T    + ++  A     + V        
Sbjct: 2439 IRPRDQGEYRIVAKDKDARAKLELAAVPKIKTT---DQKLVTDAGKPFIMRVPYDAYPRA 2495

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283
            +  W+ + + +      T +   + R   ++  +++DQ +Y  V+ +     +  + ++V
Sbjct: 2496 EAEWFFEDTSLPVQNIDTSVDKTEYR---LKSPSKEDQGQYKVVISNKHGAAEAFIVLDV 2552

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND-----EWIVNSKIIKKCKHTKPSI 1338
            ++ P  +    +  R+   +D  + + ++  P+ +       ++V  + +K+      + 
Sbjct: 2553 IDVPGSV----KNLRVLDTADGEVSLAWEE-PESDGGSKIIAYVVERRDVKRKTWALATD 2607

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA------DVEMNVTILDKPSPPGKPNILEI 1392
             + +    +  +    A ++++   N  G        D        D P  P    +  +
Sbjct: 2608 RADTPEYCVTGLHKDSAYLFRVCARNRVGSGPAVVTEDAVQAKNKFDVPDAPEDVAVETV 2667

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450
            +     I W  P+  G S I  YV+E ++  + +W +    +    S  + ++  N  Y 
Sbjct: 2668 NKFGATISWKPPKFDGGSEITAYVIELRDRTSVKWEATLECSPHDLSATLNDVVENKEYI 2727

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
            FR  A N   +   S  T   K++   +  SP
Sbjct: 2728 FRVRAENRAGVGRPSPATNPVKIMDPIERPSP 2759



 Score =  125 bits (302), Expect = 1e-26
 Identities = 183/893 (20%), Positives = 352/893 (39%), Gaps = 74/893 (8%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVK 1249
            ++E  +  T+ +PE +   A     +   +  +   +  W + +  +  + +  +     
Sbjct: 7655 IKEQMLEPTILMPESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGN 7714

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               LII+  +  D  EY+ V  ++ S  T  LK+ + + P      E    I        
Sbjct: 7715 LCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPP---EGPVEISDIDSDAC 7771

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKS-ASLTIKKVENTDAGIYKLRL 1362
             + +   P  +    + + +++KC  ++     ++ S S  S  + K+      ++++R 
Sbjct: 7772 SLSWNK-PLEDGGSNITNYVVEKCDVSRGDWVTAVSSVSKTSCRLGKLIPGKEYVFRIRA 7830

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPN---ILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
            EN  G +D   +  ++ K  P G+P    I + +   + + WD+P   G S I  Y +E 
Sbjct: 7831 ENRFGLSDPIQSDRMVAK-FPFGEPLNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIER 7889

Query: 1420 QEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            +E ++  ++   +  +  TQ     L     Y F+  A+N    S  S  T  Y V   T
Sbjct: 7890 KERNSLFFVKANDTIVRTTQYPCAGLIKGLEYTFKVSAINRACQSKPSANT--YFVTART 7947

Query: 1478 KIQSPTVEKPL---KN----ITTEPNEDIELTCIFGGVPQPKV---TWYRDGKKLKTAKA 1527
             + +P   + L   KN    + T P  D     I   V   +V   +W R     +    
Sbjct: 7948 PVYTPGKPEVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPK 8007

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHK 1585
                                   +  +   E     +V  +  P     N  +++  K K
Sbjct: 8008 EEYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKGLKVK 8067

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
             G   ++ A + G P P V W +  N L++ +   IT +     + +  + + H+  YTI
Sbjct: 8068 AGATVILEAEVFGKPMPRVTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKEHTGVYTI 8127

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYA 1702
             A N                 + P GP++   + + +  ++++ W  P +DGG  +  Y 
Sbjct: 8128 LAEN-----------------ATPPGPIVNPSVTDTTYSTISLAWTAPANDGGSPVIGYL 8170

Query: 1703 IEKHEPDNNRWIKVADVDRDVE--TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759
            +E    +   WI+  ++ R+++  +Y IQ L +  EY  R+ A N VGFSE +E     V
Sbjct: 8171 VECKRANTADWIR-CNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVGFSEPVEVPGKHV 8229

Query: 1760 IKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818
             K  +  P           ++ N    +    + K    P I +  ++    K  +    
Sbjct: 8230 AKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITW-AKMNTNIKDRQGIVI 8288

Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   I  +     Y    Y  N    SL       I + K    P  P N +V E++
Sbjct: 8289 KSSNTDTIVMVENVNRYDAGKYIFNL--ESLAGMKMYTIVV-KVYDTPGPPVNLMVKETS 8345

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
                ++ W  P ++GG  +T+YI+E +  + K+W+ IV++  +     + ++       F
Sbjct: 8346 KDGASIFWDSPLTDGGYEVTHYIVEKRDTERKAWS-IVSMNCNKTSFEVPDLNAGRSYCF 8404

Query: 1939 RISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWGTPEWDGG 1995
            R+S  N +G     E + SVR  +       P A ++ +  +V  +    SW  P  DGG
Sbjct: 8405 RVSGVNKLGAGEYCETADSVRASEE------PGAVMDFKTVLVTKDSCTISWKKPLSDGG 8458

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            + ++ Y + + +     + E+  +    ++++ +DL E   Y  R+ A N+ G
Sbjct: 8459 SRIISYVLEVLN-GDDKYKEL--MRSKNMQYSAKDLVEGKEYTYRVKAINDSG 8508



 Score =  121 bits (292), Expect = 2e-25
 Identities = 65/198 (32%), Positives = 107/198 (54%), Gaps = 7/198 (3%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT--KIVTVGGSV 1922
            PP  P N +  E T   + ++W  P+ +GG+PITNY++E K VK K W    +V+  G+ 
Sbjct: 6607 PPVGPINIL--EVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVK-KPWEPWSVVSSSGTN 6663

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
             +  +  +++  E + R+ AEN +G+S   ES     +     P PP  P+    +  N 
Sbjct: 6664 TKAKVSRLEKGREYVVRVRAENKIGISTGLESPPTIAKHMFNPPGPPGLPV-CSDITENA 6722

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            V   W  P++DGG+P+ GY I  R++T   W+ V K  V  L++ +  L E ++Y  R++
Sbjct: 6723 VTVEWTLPDYDGGSPISGYVIERREMTGK-WIRVNKTPVLDLRYRVSGLFEGNSYEFRVF 6781

Query: 2043 ARNEIGLSEPLESDEPFK 2060
            A N  G+S+P  + +P K
Sbjct: 6782 AENIAGISDPSLASDPVK 6799



 Score =  119 bits (287), Expect = 8e-25
 Identities = 94/325 (28%), Positives = 133/325 (40%), Gaps = 11/325 (3%)

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            + A NP G  E    E + + T LDVP           I +E V ++W    +NGGSPI 
Sbjct: 8999 ITASNPFGVKE----ETVKV-TVLDVPDSPGPIECSG-ISSEKVALSWTAPTENGGSPIK 9052

Query: 1801 DYKVEIKQEGKK-WKXXXXXXXXXARIQ-KLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             Y +E ++  +  W            +  KL     Y FR+ A N+ G S P  S+  + 
Sbjct: 9053 YYTLEKRETSRLLWTVLEEKVVDCHYVAYKLIQGNEYFFRVSAVNQYGASEPSHSE-AVK 9111

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
            +     PP  P    V +    S T+ W  P  +GGS I  Y +E K  KG  W +    
Sbjct: 9112 MVDRFGPPGPPSKPEVEKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRASKK 9171

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977
              +     +  + E  E  FR+ AEN  G   P+E S  VR    A  P PP  P  I  
Sbjct: 9172 SIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNP-RITD 9230

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
                    +WG P  +GG  + GY I  +      W++         +F + +L     Y
Sbjct: 9231 TTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAKY 9290

Query: 2038 MIRIYARNEIGLSEPLESDEPFKVI 2062
              RI A N  G  EP E+ E  ++I
Sbjct: 9291 HFRISAVNSKGAGEPAETSELVEII 9315



 Score =  118 bits (284), Expect = 2e-24
 Identities = 117/476 (24%), Positives = 192/476 (40%), Gaps = 33/476 (6%)

Query: 1600 PPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            PPP+    ++   LE +KE +N  T  K   + +  LK S   K+ + A N  G S    
Sbjct: 7589 PPPQPPVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTE 7648

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN-RWIKVA 1717
            T +  +   +   P I+     ESV+          G +L   A+   +P    +W++  
Sbjct: 7649 TREPVEIKEQMLEPTILMP---ESVSAR-------AGAKLRVEAVVAGKPAPMCKWMRGE 7698

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTAL-----DVPSXXX 1771
            D         + +    C  + + +++   G +S   E+    +  AL     D+P    
Sbjct: 7699 DAVVPSSRLAVHQSGNLCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPPE 7758

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKL 1829
                   ID+++  ++W    ++GGS I +Y VE     +  W          + R+ KL
Sbjct: 7759 GPVEISDIDSDACSLSWNKPLEDGGSNITNYVVEKCDVSRGDWVTAVSSVSKTSCRLGKL 7818

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
                 Y FRI A N  G S P  SD  +       P  +P N  +S++    + + W +P
Sbjct: 7819 IPGKEYVFRIRAENRFGLSDPIQSDRMVA----KFPFGEPLNCCISKTNKDCMFVAWDKP 7874

Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
              +GGSPIT Y IE K      + K   T+  +    C   IK   E  F++SA N    
Sbjct: 7875 SGDGGSPITGYYIERKERNSLFFVKANDTIVRTTQYPCAGLIKGL-EYTFKVSAINRACQ 7933

Query: 1949 SLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
            S P+  +  V        P  P    E+  +  N V   W  P+ DGG+ ++GY +    
Sbjct: 7934 SKPSANTYFVTARTPVYTPGKP----EVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMR 7989

Query: 2008 VTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            V    W+       N  K  + +  L  +  Y  R+ A+  + +S+P E  +P  V
Sbjct: 7990 VPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLV 8045



 Score =  118 bits (283), Expect = 2e-24
 Identities = 93/321 (28%), Positives = 143/321 (44%), Gaps = 27/321 (8%)

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
            LES  +   TA  +P             N S  ++W   E +GGSPI  Y +E ++  KK
Sbjct: 3973 LESTLLFCTTATGLPGQCKDIRSTDITKN-SCQVSWEMPEDDGGSPISSYTLERREASKK 4031

Query: 1813 --WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL------PYTSDD------KIT 1858
                           ++ L +N  Y FR+ A N++G         P  +++       + 
Sbjct: 4032 TYMPVLSGENVLTHTVKDLYVNCEYFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLI 4091

Query: 1859 IGKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
            +   LT  P  P      + TS+S+T+ W  P+++GG PI  YI+E     G  + ++  
Sbjct: 4092 LNFDLTEKPDPPLQVETCDPTSKSITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTP 4151

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
                     +  +KE  E  FR+ AEN  GVS P  S+S +L K A     P AP+    
Sbjct: 4152 SLVPGFSFVVTGLKENMEYQFRVRAENVAGVSEP--SRSTQLLKAADPVDKPGAPINFTF 4209

Query: 1978 --VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV-NTLK---FNIRDL 2031
              + +  V+ +W  PE DGG+ +L Y +  RD  K    EVG + + +TLK   F +  L
Sbjct: 4210 DEIRNTSVICNWEPPEDDGGSEILNYILEKRDYKKE---EVGWITITSTLKGNSFPVTKL 4266

Query: 2032 SENHTYMIRIYARNEIGLSEP 2052
             E   Y+ R+ A N+ G   P
Sbjct: 4267 IEGKEYIFRVTAENKFGCGPP 4287



 Score =  116 bits (279), Expect = 7e-24
 Identities = 159/713 (22%), Positives = 269/713 (37%), Gaps = 65/713 (9%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE------------- 1426
            KP P  K  +LEI  +S  + W +P   G + I  YV+EY E+   E             
Sbjct: 7538 KPDPCEKIEVLEITKNSATVGWIKPARDGGAKIDGYVIEYIEVHEGEEPPPPPPQPPVVE 7597

Query: 1427 -----------WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
                       W +   +   + S+  LK +  Y+FR  A N + +S  +ET E  + IK
Sbjct: 7598 DEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTETREPVE-IK 7656

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--DGKKLKTAKATYE--N 1531
            E  ++ PT+  P ++++      + +  +  G P P   W R  D     +  A ++  N
Sbjct: 7657 EQMLE-PTILMP-ESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGN 7714

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ---KPVITISNEDIKQKHKVGD 1588
                            Y  +A N   +V  +  + I+     P   +   DI        
Sbjct: 7715 LCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPPEGPVEISDI-DSDACSL 7773

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
             W       G      +  +  +    D    +++  KTS  R+ +L       + I A 
Sbjct: 7774 SWNKPLEDGGSNITNYV-VEKCDVSRGDWVTAVSSVSKTS-CRLGKLIPGKEYVFRIRAE 7831

Query: 1649 NTAGTSS-VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
            N  G S  ++    V   P        + + +++ + + W  P  DGG  +T Y IE+ E
Sbjct: 7832 NRFGLSDPIQSDRMVAKFPFGEPLNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIERKE 7891

Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
             ++  ++K  D       Y    L +  EY F+V A N     ++  S      TA   P
Sbjct: 7892 RNSLFFVKANDTIVRTTQYPCAGLIKGLEYTFKVSAINRA--CQSKPSANTYFVTA-RTP 7948

Query: 1768 SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXAR- 1825
                       I   SV + W   + +GGS II Y VE ++  G  W           + 
Sbjct: 7949 VYTPGKPEVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKE 8008

Query: 1826 ---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
               +  L  +  YQFR+ A+  +  S P    D + +     PP    N  + +      
Sbjct: 8009 EYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKG----- 8063

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
             LK       G + I    +  K +   +W +    G +  + C   +       F++  
Sbjct: 8064 -LK----VKAGATVILEAEVFGKPMPRVTWKR----GDNSLKSCEGQVITHQRHHFQL-- 8112

Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
            E T      T   ++ L ++AT P P   P       S I + +W  P  DGG+P++GY 
Sbjct: 8113 EMTAVTKEHTGVYTI-LAENATPPGPIVNPSVTDTTYSTISL-AWTAPANDGGSPVIGYL 8170

Query: 2003 IAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            +  +      W+      ++    + I++L + + Y  RI A N +G SEP+E
Sbjct: 8171 VECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVGFSEPVE 8223



 Score =  115 bits (277), Expect = 1e-23
 Identities = 77/302 (25%), Positives = 129/302 (42%), Gaps = 13/302 (4%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXX-ARIQKLSINTTY 1835
            I  +  ++ W   E NGG  I +Y +E K E K+  W            ++ +L     Y
Sbjct: 7103 ISIDRCHLAWEAPEDNGGCDIYNYIIE-KCETKRGVWSVHSNAVITNKTKVTRLIEGNEY 7161

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             FR+ A N++G   P    + I  G   + P  P    V++     +T++W+EPE +GG 
Sbjct: 7162 IFRVRAENKMGPG-PAVQSEPIVAGTQFSVPYAPEMPEVTKIAKEEMTVQWSEPEKDGGK 7220

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            PIT Y++E +      W+ +           +  +    +  +R+ A N +G+S P++S 
Sbjct: 7221 PITGYLLEKREEHAVRWSPVNKDPTPATHFTVTGLIPLHDYQYRVKAVNEIGISSPSKSS 7280

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--- 2012
                 K A  P  P + L +     + V   W  P   GGAP++GY + +R         
Sbjct: 7281 RAVTAKDAVGPPAPPSNLRVLDSTKSTVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGD 7340

Query: 2013 --WMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHA 2069
              W        +    F +  L +   Y  R+ A+N++G+S P +  +   VIP E   A
Sbjct: 7341 DGWKRCNVAAQLVVCDFTVTSLDDQLVYEFRVSAQNQVGMSLPCDLKD--AVIPKEILEA 7398

Query: 2070 DE 2071
             E
Sbjct: 7399 PE 7400



 Score =  113 bits (272), Expect = 5e-23
 Identities = 134/608 (22%), Positives = 246/608 (40%), Gaps = 47/608 (7%)

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKF--TLISDVKK 1250
            P ++    + E ++V A     +   +  + T D+TW +  S +    K   T IS    
Sbjct: 5743 PEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRDGSALPPEAKVETTFISSA-- 5800

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKRGSDVTL 1307
              LII+ C+      YT    +A    K  + VEV++ P P  + +  E        +  
Sbjct: 5801 --LIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVLDVPGPVGIPFTTENLSNDSCKLNW 5858

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
                     P   +IV  +  ++   T  S  +   +     + +  +  +++  EN  G
Sbjct: 5859 FFPENDGGSPISNYIVEKREAERKAWTSVSFTASRTNAVAHGLTSGKSYFFRVAAENAIG 5918

Query: 1368 ---HADVEMNVTILDKPSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQE 1421
                 +    V I +  S P +P  LE+   +   I++ W  P++ G S I  Y++E + 
Sbjct: 5919 IGPFVETAAEVVIREPISIPERPEELEVHKVTKDLISVTWKPPKSDGGSEITMYILEARM 5978

Query: 1422 I--DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            I  D    ++ + + + + +   L+   +Y FR  AVNEV     S  T+   +  + ++
Sbjct: 5979 IGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRVIAVNEVGPGKPSFCTK--PITCKDEL 6036

Query: 1480 QSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXX 1537
            + PT+E   ++ I     E   L   + G P P + WYRD +++K  K   ++N      
Sbjct: 6037 EPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTLTTMS 6096

Query: 1538 ---XXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                         Y  +  N  G  +  C   VVG+ + P +      +++ +      L
Sbjct: 6097 LGLMKAQREHSGRYVVVVENSTGSRKGICNVTVVGVPEAPEM----PTVREVYATNALVL 6152

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEAS 1648
                 +G  P  +  Y    K    K ++  T+E     +  R+++L      ++ + A 
Sbjct: 6153 WNRPRDGGKP--ITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAE 6210

Query: 1649 NTAGTSS-VEVTLKVYDK-----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            N  GT    E +  +  K     PS P  P    + +++SV+++WK P  DG   +  Y 
Sbjct: 6211 NELGTGDPSEPSKPILAKDPIVCPSPPVTPEAY-DKTKDSVSLKWKLPRHDGKGRIFGYL 6269

Query: 1703 IEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759
            +E  +P    WI+  +         + +  LN+  EY+FR+   N  G S+ A   EPI 
Sbjct: 6270 VEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIK 6329

Query: 1760 IKTALDVP 1767
            +   L+ P
Sbjct: 6330 VHDRLEKP 6337



 Score =  112 bits (269), Expect = 1e-22
 Identities = 65/239 (27%), Positives = 112/239 (46%), Gaps = 9/239 (3%)

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
            R++  S     Q+++   N+ G +  +   D I +      P   +N  V ++    V+L
Sbjct: 2521 RLKSPSKEDQGQYKVVISNKHGAAEAFIVLDVIDV------PGSVKNLRVLDTADGEVSL 2574

Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
             W EPES+GGS I  Y++E + VK K+W  + T      E+C+  + +    +FR+ A N
Sbjct: 2575 AWEEPESDGGSKIIAYVVERRDVKRKTWA-LATDRADTPEYCVTGLHKDSAYLFRVCARN 2633

Query: 1945 TVGVSLPTESQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
             VG      ++ +V+ +    VP  P   + +  V       SW  P++DGG+ +  Y I
Sbjct: 2634 RVGSGPAVVTEDAVQAKNKFDVPDAPE-DVAVETVNKFGATISWKPPKFDGGSEITAYVI 2692

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
             +RD T   W    +   + L   + D+ EN  Y+ R+ A N  G+  P  +  P K++
Sbjct: 2693 ELRDRTSVKWEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIM 2751



 Score =  109 bits (262), Expect = 8e-22
 Identities = 63/202 (31%), Positives = 97/202 (48%), Gaps = 8/202 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  PR+  VS+ T  +  L W  P+ +GG  + +Y IE KTV GK+WTK V    +    
Sbjct: 5338 PGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIEKKTVHGKAWTK-VNPACAAQSL 5396

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
             + ++    E +FRI AEN  G    T++ +  +       P PPT  L+I+ V    V 
Sbjct: 5397 VVPDLNNGQEYLFRIRAENRFGFGPFTQTIERTKASDPINPPDPPTR-LKIQNVHKGAVT 5455

Query: 1985 TSWGTPEWDGGAPLLGYNIAI-----RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
             +W  P+ DGG+P+  Y++ +         K  W    + DV + +F + DL+    Y  
Sbjct: 5456 LTWKAPKNDGGSPVTHYSVDLLCWDASGTQKEHWRRCNRRDVESTRFKVEDLTYGDEYEF 5515

Query: 2040 RIYARNEIGLSEPLESDEPFKV 2061
            R+ A NE G S P  +  P  +
Sbjct: 5516 RVVAYNEAGPSRPSTTAGPITI 5537



 Score =  102 bits (245), Expect = 9e-20
 Identities = 105/427 (24%), Positives = 182/427 (42%), Gaps = 38/427 (8%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
            G+ A FE +++   A+  W KDG  ++     + T DGK +KL I D  L D GEY+C  
Sbjct: 552  GSSAVFECQISPSTAITSWMKDGGNLREGPKYKFTADGKDRKLNILDVQLSDTGEYTCVA 611

Query: 1181 GNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
             N+     CTA L VEE  + +   L            YLT E+  E  DVTW +  +V+
Sbjct: 612  RNAGKEITCTAKLIVEELPVKWVKELEPETTCMKGQPMYLTCELNKER-DVTWKRNGAVL 670

Query: 1237 EDTEKFTLISDV-KKRTLIIRKCTEDDQCEYTCVL---LDAKSTTKLKV-EVVEFPPKIV 1291
            +       I+ +  +  + I+  TE+D   YTC +    D  +TT +KV E+++    +V
Sbjct: 671  KKKAGKVAINIIGLQHAVTIQNATEEDTGAYTCEVEGREDISTTTNVKVLEIIK--DWLV 728

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               R+  +K  S  T   +      PN +W+     I   +  + + D  + +LTI   +
Sbjct: 729  KPLRDQHVKPKSKATFKGELFK-DTPNWKWLKGETEITPSEKMEIAKDGANVTLTINNCQ 787

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              D   Y + +E+    A + +   +  +     +  IL+   +S+ +   E  N     
Sbjct: 788  PDDVSEYTIEVEDRRYTAKLTLGGAV-RRRFQEREAEILK-PLASLEVVEKEEAN----- 840

Query: 1412 IIYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
               +  E  E D   EW  ++    T++   ++K     RF    +  V +  A E +  
Sbjct: 841  ---FDTEISEEDIIGEW-KLRGQVLTRSPTCDIKLEGRKRF--LTLKNVQVDQAGEVS-- 892

Query: 1471 YKVIKETKIQSPTVEK-------PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            Y+ +        TV++       PLK+++    +  +  C       PKV W++ G ++ 
Sbjct: 893  YQALNAVTTGMLTVKELEMGFVDPLKDVSVPEKKQAKFECTV-TKEVPKVMWFK-GAEIV 950

Query: 1524 TAKATYE 1530
            T    YE
Sbjct: 951  TPGPKYE 957



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 60/193 (31%), Positives = 87/193 (45%), Gaps = 2/193 (1%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            L  P   ++  VS  +     L W  PE NGG  I NYIIE    K   W+ + +     
Sbjct: 7089 LDRPGPVQDLKVSGISIDRCHLAWEAPEDNGGCDIYNYIIEKCETKRGVWS-VHSNAVIT 7147

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
            ++  +  + E +E IFR+ AEN +G     +S+ +      +VP  P  P E+  +    
Sbjct: 7148 NKTKVTRLIEGNEYIFRVRAENKMGPGPAVQSEPIVAGTQFSVPYAPEMP-EVTKIAKEE 7206

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            +   W  PE DGG P+ GY +  R+     W  V K       F +  L   H Y  R+ 
Sbjct: 7207 MTVQWSEPEKDGGKPITGYLLEKREEHAVRWSPVNKDPTPATHFTVTGLIPLHDYQYRVK 7266

Query: 2043 ARNEIGLSEPLES 2055
            A NEIG+S P +S
Sbjct: 7267 AVNEIGISSPSKS 7279



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 1/168 (0%)

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            + G+ + L  D +  P P  +W     +++             + L+I      D   Y 
Sbjct: 3168 RAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYI 3227

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
            +   N CG A   ++V ILDKP PP   +I EI S S  + W+ P + G S I  Y+VE 
Sbjct: 3228 IEAVNVCGRATATIDVNILDKPGPPAAFDISEITSESCCLAWNPPRDDGGSPITNYIVES 3287

Query: 1420 QEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            ++ D  EWI +    K T      L     Y FR  A N+  I + +E
Sbjct: 3288 RQTDKEEWIKLSATVKHTTFKACKLTGMKEYIFRISAENQFGIGEPAE 3335



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 56/208 (26%), Positives = 95/208 (45%), Gaps = 14/208 (6%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P Q ++   ++ T  S  + W  PE +GGSPI++Y +E +    K++  +++ G +V  H
Sbjct: 3987 PGQCKDIRSTDITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLS-GENVLTH 4045

Query: 1926 CIENIKEKDEIIFRISAENTVGVSL------PTESQSVRLEKHATV-----PSPPTAPLE 1974
             ++++    E  FR+ A N VG         P  ++ V+L  +  +        P  PL+
Sbjct: 4046 TVKDLYVNCEYFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQ 4105

Query: 1975 IRMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            +      S  +  +W  P+ DGG P+ GY +   +     +  V    V    F +  L 
Sbjct: 4106 VETCDPTSKSITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLK 4165

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            EN  Y  R+ A N  G+SEP  S +  K
Sbjct: 4166 ENMEYQFRVRAENVAGVSEPSRSTQLLK 4193



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 51/172 (29%), Positives = 78/172 (45%), Gaps = 4/172 (2%)

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            K G+ + L       P P  +W+ + K I             S  L+I + +  D G Y 
Sbjct: 6524 KAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYV 6583

Query: 1360 LRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
            L + N  G   V ++VT+LD P PP G  NILE+    + I W  P++ G + I  YVVE
Sbjct: 6584 LIVTNPAGSKTVALHVTVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVE 6643

Query: 1419 YQEIDT--TEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
             +++      W  V +  T T+  +  L+    Y  R  A N++ IS   E+
Sbjct: 6644 KKDVKKPWEPWSVVSSSGTNTKAKVSRLEKGREYVVRVRAENKIGISTGLES 6695



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 88/413 (21%), Positives = 169/413 (40%), Gaps = 39/413 (9%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITI 791
            + P+   PL+ + V +GE + L   V+G+P   + W K+ + +K+   T+      S+ +
Sbjct: 4    QAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCL 63

Query: 792  LKPKKVKDE-GVYTLKAENSEGIAETSAVITVEE------PTE----------ENAEPPL 834
                  K E G Y  KA N+ G     + ++V+E      P E             +   
Sbjct: 64   EVEAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRRLDNLF 123

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVIT 893
            FI   + I+  EKGT   +A++   P+P++ W +     I+P   I+ +  G++ ++ I 
Sbjct: 124  FIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDAKMEIR 183

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---------KVTFVKHLQKSYETEEGK 944
             V ++ DSG Y+CVASN  G+    A + +  +         +V   K   K    ++ +
Sbjct: 184  EV-TKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGEFGDVRVMLKKTPSKQKSPKKEE 242

Query: 945  TVILECQTSHTVSTKWYHN-KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
              I+E    H    K Y    +E    D+R I+Q                V  +  + ++
Sbjct: 243  WNIVELLRGH--DPKEYEKILQEHDIHDYRAILQAMDLLKKEKEAEPSKTVDQVDRVEEE 300

Query: 1004 QETSTMLVVKETIP----EFIRKLQDFEVKEKDVAIL--EVEINSETADVVWERDGEIIK 1057
                 +  ++  I       +  + D +  E   A     ++IN     + W +    ++
Sbjct: 301  DMARFIQQLESHIAAEPVSVLEDITDQKTAENQSATFRCRIQINYPEISLTWYKGTRRLE 360

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII 1110
             + +KY+    G +  L + +    DEG+Y  +      TA + V    P+++
Sbjct: 361  -QGHKYEISSVGDLHCLKVNDCDPSDEGDYRVVCGPHISTAMLAVAGKCPDLL 412



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 62/268 (23%), Positives = 116/268 (43%), Gaps = 13/268 (4%)

Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
            P+++ + +++ E + W            +  L  +  Y+FR+ A+N +G SL   + + +
Sbjct: 7594 PVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTETREPV 7653

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWTKI 1915
             I + +  P+     ++ ES S     K        G  +P+  ++     V   S    
Sbjct: 7654 EIKEQMLEPT----ILMPESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSS-RLA 7708

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
            V   G++    I+++   D   + + AEN+   S  T++  + +     +P PP  P+EI
Sbjct: 7709 VHQSGNLCVLIIKDVSRTDSGEYSLVAENSS--SKVTQALKIVIRD---IPGPPEGPVEI 7763

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              + S+    SW  P  DGG+ +  Y +   DV++  W+      V+     +  L    
Sbjct: 7764 SDIDSDACSLSWNKPLEDGGSNITNYVVEKCDVSRGDWV-TAVSSVSKTSCRLGKLIPGK 7822

Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             Y+ RI A N  GLS+P++SD      P
Sbjct: 7823 EYVFRIRAENRFGLSDPIQSDRMVAKFP 7850



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 11/205 (5%)

Query: 1793 KNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTS 1848
            ++GG PI +Y +E K+   K+W          A   R+Q L     Y+FR+ A NE+GT 
Sbjct: 6157 RDGGKPITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAENELGTG 6216

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
             P      I     +  PS P      + T  SV+LKW  P  +G   I  Y++E+K   
Sbjct: 6217 DPSEPSKPILAKDPIVCPSPPVTPEAYDKTKDSVSLKWKLPRHDGKGRIFGYLVEYKKPG 6276

Query: 1909 GKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAENTVGVSLPT---ESQSV--RLEK 1961
               W +           +  +  + +  E +FRI   N  G S P    E   V  RLEK
Sbjct: 6277 AVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIKVHDRLEK 6336

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTS 1986
               +     A   + M+G++I +++
Sbjct: 6337 PELLLDANMARDHLAMLGTDITLSA 6361



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 10/288 (3%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250
            E P I   ++L   +   A T   L  ++  +    V W K   V+   ++ T+ +    
Sbjct: 3151 EPPEIQLDVKLLAGLTARAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDH 3210

Query: 1251 RTLIIRKCTEDDQCEYT--CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
              L I   T  D   Y    V +  ++T  + V +++ P     ++          +   
Sbjct: 3211 SKLSIANTTRGDTATYIIEAVNVCGRATATIDVNILDKPGPPAAFDISEITSESCCLAWN 3270

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                    P   +IV S+   K +  K S   K  +    K+      I+++  EN  G 
Sbjct: 3271 PPRDDGGSPITNYIVESRQTDKEEWIKLSATVKHTTFKACKLTGMKEYIFRISAENQFGI 3330

Query: 1369 ADVEMNVTILDKPS--PPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
             +   +V I+ K S  PPG P  +   +I   ++ + W EP+  G S I  Y VE  + +
Sbjct: 3331 GEPAEHVPIVAKYSFDPPGSPTRVTPSDITKDAVTLTWFEPDEDGGSPITGYWVEKFDPE 3390

Query: 1424 TTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + +WI    +    TS  ++ L+T   YRFR  A N      AS  T+
Sbjct: 3391 SEKWIRCNKLPVKDTSFRVKGLRTKKKYRFRVLAENLAGPGKASSETD 3438



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 22/314 (7%)

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRT 1252
            P+I   ++L E ++  A T   L  ++    +    W      I    +  + +      
Sbjct: 6509 PTIEVDVKLIEGVIAKAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTI 6568

Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            L I +C   D  EY  ++ +     T  L V V++ P   V       I   +   +++ 
Sbjct: 6569 LSISECQRGDTGEYVLIVTNPAGSKTVALHVTVLDLPGPPVG---PINILEVTPDYMMIQ 6625

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDAG---IYKLRLE 1363
            ++A P+ +    + + +++K    KP    S+ S S + T  KV   + G   + ++R E
Sbjct: 6626 WRA-PKDDGGTPITNYVVEKKDVKKPWEPWSVVSSSGTNTKAKVSRLEKGREYVVRVRAE 6684

Query: 1364 NNCG-HADVEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
            N  G    +E   TI     + P PPG P   +I  +++ + W  P+  G S I  YV+E
Sbjct: 6685 NKIGISTGLESPPTIAKHMFNPPGPPGLPVCSDITENAVTVEWTLPDYDGGSPISGYVIE 6744

Query: 1419 YQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             +E+ T +WI V    +   +  +  L   +SY FR +A N   ISD S  ++  K  + 
Sbjct: 6745 RREM-TGKWIRVNKTPVLDLRYRVSGLFEGNSYEFRVFAENIAGISDPSLASDPVKAARA 6803

Query: 1477 TKIQSPTVEKPLKN 1490
                 P     L++
Sbjct: 6804 ITRPGPPGNPKLRD 6817



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 38/179 (21%), Positives = 73/179 (40%), Gaps = 1/179 (0%)

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
            +T+ V    +P P   WI   K +   +            LT+      D G Y L+LEN
Sbjct: 2877 LTIRVPITGYPTPVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLEN 2936

Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
            +      E+ V ++  PS P    + E+    +++ W+ PE+ G S + +Y +E +E+  
Sbjct: 2937 DISSVSGEVEVNVIACPSAPKDFKVAEVSRHHVHLMWEAPEHDGGSPVTHYQIEKREVSR 2996

Query: 1425 TEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
              W+ V   +   + ++ ++     Y F   A N+    + +   E   +     +  P
Sbjct: 2997 KTWVKVASGVLDLEHTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDP 3055



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 73/370 (19%), Positives = 149/370 (40%), Gaps = 30/370 (8%)

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADV-EM 1373
            P   ++V  + +++   T  S+D+  K     +  +      ++++  EN+ G ++  E+
Sbjct: 3579 PITNYVVEKRDVRR--KTWQSVDTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCEL 3636

Query: 1374 NVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
               +L K     P PP    +LE+    + + W+ P++ G   I  YV+E +E   T W+
Sbjct: 3637 EDAVLAKDTFTTPGPPYALTVLEVTKRHVELKWEAPKSDGGRPITKYVIEKKEKLGTRWL 3696

Query: 1429 S-VKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
               K   K +Q  + ++   S  +F+  A NE  + D SE TE   +   T   SP ++ 
Sbjct: 3697 KCCKTPDKQSQFKVTDVDEGSEVQFQVRAENEAGVGDPSEPTEILNIEDPTSAPSPPLDL 3756

Query: 1487 PLKNITTEP-NEDIELTCIFGGVP-----------QPKVTWYR-DGKKLKTAKATYENRX 1533
             + + + E      +     GG P           +P++ W R + + +K  K   ++  
Sbjct: 3757 TIPDASREHITATWKPPAKDGGCPISGYHVEVAEARPELKWLRVNNRPIKELKFRIDD-- 3814

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLV 1592
                             +   D  E+            P + +  +DI      G++  +
Sbjct: 3815 GIKPEKKYVIRVRAINSVGTGDPSEITDKIFTKDPDSAPTLKLEAQDIVVIE--GEKLHL 3872

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                + IP P ++W K+  + + D   ++T +   + + + +   + +  YTI   N  G
Sbjct: 3873 KVPYKAIPTPTMVWQKDTLECKVDDRLSMTLEMNDAHLELLKCTHADAGTYTIVLKNALG 3932

Query: 1653 TSSVEVTLKV 1662
              +  V +KV
Sbjct: 3933 MVTGTVNVKV 3942



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 40/137 (29%), Positives = 69/137 (50%), Gaps = 8/137 (5%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            A + G PPP+V W + G  ++N  ++  +   +  + + + +  R  S KY +   + AG
Sbjct: 7423 ATVRGRPPPKVTWRRMG--IDNVVRKGKVDIIDTMTFLLVPDSTRDDSGKYCLTVQSLAG 7480

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE----P 1708
              +V V +KV D P  P   +   +I + S  + W PP +DGG E+  Y +EK E    P
Sbjct: 7481 EKAVFVNVKVLDTPG-PVMNLEATDIKQTSAMLSWTPPENDGGSEILHYIVEKREIDRKP 7539

Query: 1709 DNNRWIKVADVDRDVET 1725
            D    I+V ++ ++  T
Sbjct: 7540 DPCEKIEVLEITKNSAT 7556



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            PS PRN VVSE TS S  L W  PE NGG+ I++Y++E K V  + W  +      +   
Sbjct: 6380 PSPPRNLVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLM 6439

Query: 1926 CIENIKEKDEIIFRISAENTVGVS 1949
             +  + E  + +FR++AEN  G S
Sbjct: 6440 AM-YLMEGIQYLFRVAAENQFGRS 6462



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 3/148 (2%)

Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKN 1432
            + +   P PP  P I +   ++  + W +P + G   I  Y++E+++  T +W+  ++  
Sbjct: 9214 IAVAFPPGPPVNPRITDTTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSP 9273

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNI 1491
               T+  +  L+T + Y FR  AVN     + +ET+E  ++I+        ++  L + +
Sbjct: 9274 HRITEFVVAELETGAKYHFRISAVNSKGAGEPAETSELVEIIERASEPDLELDVELRRTL 9333

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
                   I L     G P P VTW ++G
Sbjct: 9334 VVRACCSIRLFVPIKGRPTPTVTWTKEG 9361



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 6/168 (3%)

Query: 1625 EKTSVIRIKELKRSH----SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            EK  ++    + R H     +  T+ A+     + V    K  DKPS P   +++ E++ 
Sbjct: 6335 EKPELLLDANMARDHLAMLGTDITLSATLKGVPTPVVSWKKNNDKPSPPRN-LVVSEVTS 6393

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
            ES  + WK P D+GG  ++ Y +EK +    +W+ V+  ++ +    +  L E  +Y+FR
Sbjct: 6394 ESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLMAMY-LMEGIQYLFR 6452

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
            V A+N  G S+ + ++  V       P            D   V++ W
Sbjct: 6453 VAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHHTDADKTEVWLAW 6500



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 2/127 (1%)

Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
            H++    V     P PP KP + ++D  S  + W  P + G S II Y VE +E   T W
Sbjct: 9106 HSEAVKMVDRFGPPGPPSKPEVEKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRW 9165

Query: 1428 I--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
            +  S K+I +    +  L  +  Y FR +A N     + SE +   + I       P V 
Sbjct: 9166 VRASKKSIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVN 9225

Query: 1486 KPLKNIT 1492
              + + T
Sbjct: 9226 PRITDTT 9232



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 9/193 (4%)

Query: 1282 EVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
            E++E P   +D   ++   ++    + L    +  P P   W     I    +  K  I 
Sbjct: 7394 EILEAPEIDLDAMLKQGLTVRATCPIRLCATVRGRPPPKVTWR-RMGIDNVVRKGKVDII 7452

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
                 L +      D+G Y L +++  G   V +NV +LD P P       +I  +S  +
Sbjct: 7453 DTMTFLLVPDSTRDDSGKYCLTVQSLAGEKAVFVNVKVLDTPGPVMNLEATDIKQTSAML 7512

Query: 1400 CWDEPENTGNSTIIYYVVEYQEI----DTTEWISVKNITKTQTSIQNLK--TNSSYRFRA 1453
             W  PEN G S I++Y+VE +EI    D  E I V  ITK   ++  +K   +   +   
Sbjct: 7513 SWTPPENDGGSEILHYIVEKREIDRKPDPCEKIEVLEITKNSATVGWIKPARDGGAKIDG 7572

Query: 1454 YAVNEVDISDASE 1466
            Y +  +++ +  E
Sbjct: 7573 YVIEYIEVHEGEE 7585



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 15/177 (8%)

Query: 1358 YKLRLENNCGHADV-EMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++  EN  G  D  E +  IL K     PSPP  P   +    S+++ W  P + G   
Sbjct: 6205 FRVMAENELGTGDPSEPSKPILAKDPIVCPSPPVTPEAYDKTKDSVSLKWKLPRHDGKGR 6264

Query: 1412 IIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
            I  Y+VEY++    EWI    S +        +  L     Y FR + VN    SD +  
Sbjct: 6265 IFGYLVEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYI 6324

Query: 1468 TEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
             E  KV    +++ P +       ++       DI L+    GVP P V+W ++  K
Sbjct: 6325 REPIKV--HDRLEKPELLLDANMARDHLAMLGTDITLSATLKGVPTPVVSWKKNNDK 6379



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 64/286 (22%), Positives = 112/286 (39%), Gaps = 13/286 (4%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS----VLKITNV 700
            V++GSDI +  ++   P P + W +K      D  + V  +  ++   S     L I   
Sbjct: 5554 VEQGSDISIIAKIRGCPFPTLTW-YKAPPHKSDNKVEVQYDEHINKIVSDDSCTLLIQQG 5612

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
            K+   G YT++A N  G+AS  + L +  G   PP      + +   +     L  +  G
Sbjct: 5613 KRPDTGLYTLMASNSLGKASKEMRLNV-LGRPGPPSAPIKFEEIGAERITLSWLPPKDDG 5671

Query: 761  NPRPT--ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET-S 817
              + T  + W +       +P  S+      T+ +      E V+ + A+N  G+ E   
Sbjct: 5672 GSKVTNYVIWRRVANRKSWVPVTSEPKERIWTV-ENLMTGHEYVFRVMAQNKYGVGEPLD 5730

Query: 818  AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
            +   V        E  L  +  +++ V   G I+++A V+  P P ITW R+   + P  
Sbjct: 5731 SEPEVARDLYIGPEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRDGSALPPEA 5790

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             +   F       +I    S    G Y   A N+ G+      V +
Sbjct: 5791 KVETTFIS---SALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEV 5833



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 63/293 (21%), Positives = 107/293 (36%), Gaps = 12/293 (4%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW---KXXXXXXXXXARIQKLSINTTYQFR 1838
            ++ + W     +GGSP+I Y VE K+     W               IQ L     YQ R
Sbjct: 8150 TISLAWTAPANDGGSPVIGYLVECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCR 8209

Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            I A N +G S P     K      +  P    +  + E    +         +  G P  
Sbjct: 8210 ITAVNRVGFSEPVEVPGKHVAKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRP 8269

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
                       K    IV    +      +EN+   D   +  + E+  G+ + T    +
Sbjct: 8270 KITWAKMNTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYIFNLESLAGMKMYT----I 8325

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
             ++ + T P PP   L ++    +     W +P  DGG  +  Y +  RD  +  W  + 
Sbjct: 8326 VVKVYDT-PGPP-VNLMVKETSKDGASIFWDSPLTDGGYEVTHYIVEKRDTERKAW-SIV 8382

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070
             ++ N   F + DL+   +Y  R+   N++G  E  E+ +  +     G+  D
Sbjct: 8383 SMNCNKTSFEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMD 8435



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 17/232 (7%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           E + AP F   L P    +G  +  +C V G P  ++ W +    +K S++ Q+ + D +
Sbjct: 1   ESAQAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGS 60

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
           V  L +      +AG + C A NAAG     + + V+           V           
Sbjct: 61  VC-LEVEAASKTEAGDYLCKASNAAGSTFCKSRVSVK-----EKEFRAVPAEAVVPAIST 114

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVA 683
               L+ +   F ++PK     E        ++   P P++ W+  K  +I P   IS+ 
Sbjct: 115 PVRRLDNL--FFIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIH 172

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE----ASLPIVLKIKTGE 731
            +       + ++I  V K   GTY  VA N+ GE    A + +  K + GE
Sbjct: 173 HKGQ----DAKMEIREVTKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGE 220



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 62/286 (21%), Positives = 112/286 (39%), Gaps = 20/286 (6%)

Query: 1639 HSSKYTIEASNTAGTSSVE-----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
            H  +Y ++A N  G SS       VT K    P  P   + + + ++ +VT+ W  P+  
Sbjct: 7259 HDYQYRVKAVNEIGISSPSKSSRAVTAKDAVGPPAPPSNLRVLDSTKSTVTLGWTKPVST 7318

Query: 1694 GGLELTKYAIEKH-----EPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            GG  +  Y +E       +  ++ W +        V  + +  L++   Y FRV AQN V
Sbjct: 7319 GGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQLVVCDFTVTSLDDQLVYEFRVSAQNQV 7378

Query: 1748 GFSEALESEPIVI-KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP--IIDYKV 1804
            G S   + +  VI K  L+ P           +   +       +   G  P  +   ++
Sbjct: 7379 GMSLPCDLKDAVIPKEILEAPEIDLDAMLKQGLTVRATCPIRLCATVRGRPPPKVTWRRM 7438

Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
             I    +K K           +   + + + ++ +  ++  G    + +       K L 
Sbjct: 7439 GIDNVVRKGKVDIIDTMTFLLVPDSTRDDSGKYCLTVQSLAGEKAVFVNV------KVLD 7492

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
             P    N   ++    S  L WT PE++GGS I +YI+E + +  K
Sbjct: 7493 TPGPVMNLEATDIKQTSAMLSWTPPENDGGSEILHYIVEKREIDRK 7538



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 92/411 (22%), Positives = 164/411 (39%), Gaps = 54/411 (13%)

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886
            E+A+ P F    + +TV E   + L   V  +P   + W ++  E+ S  ET     DG 
Sbjct: 1    ESAQAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDG- 59

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------------------- 924
            ++ L +    S+ ++GDY C ASN+AG +   +RV++                       
Sbjct: 60   SVCLEV-EAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRR 118

Query: 925  VEKVTFVKHLQKSYETEEG-KTVILECQTSHTVSTKWYHNK-KEISGMDHREIIQEGRXX 982
            ++ + F++  +    TE+G  T I +       + KW   K ++I+      I  +G+  
Sbjct: 119  LDNLFFIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDA 178

Query: 983  XXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV--KETIPEF--IR-KLQDFEVKEKD- 1032
                      D G  +C+  ++    E S  + V  K+ + EF  +R  L+    K+K  
Sbjct: 179  KMEIREVTKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGEFGDVRVMLKKTPSKQKSP 238

Query: 1033 -------VAILEVEINSETADVVWERDGEIIKPKKNKYDF---EKRGHIRKLYIRNTSVH 1082
                   V +L      E   ++ E D    +      D    EK     K   +   V 
Sbjct: 239  KKEEWNIVELLRGHDPKEYEKILQEHDIHDYRAILQAMDLLKKEKEAEPSKTVDQVDRVE 298

Query: 1083 DEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF--EIELTKGDALVRWF 1140
            +E     I + ES      +   P  ++  + +QK  +   ATF   I++   +  + W+
Sbjct: 299  EEDMARFIQQLES-----HIAAEPVSVLEDITDQKTAENQSATFRCRIQINYPEISLTWY 353

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
            K    ++  +  +++  G    LK+ DCD  D G+Y    G    TA+L V
Sbjct: 354  KGTRRLEQGHKYEISSVGDLHCLKVNDCDPSDEGDYRVVCGPHISTAMLAV 404



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 94/488 (19%), Positives = 186/488 (38%), Gaps = 34/488 (6%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKV 1662
            W  +G + E+ +  N    E T   ++++L      ++ + A N AG S    T   + +
Sbjct: 5479 WDASGTQKEHWRRCNRRDVESTR-FKVEDLTYGDEYEFRVVAYNEAGPSRPSTTAGPITI 5537

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVAD- 1718
             D+   P   + ++E        +        G     LT Y    H+ DN   ++  + 
Sbjct: 5538 QDQSCAPS--IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEH 5595

Query: 1719 ----VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
                V  D  T  IQ+       ++ ++A N +G     ++   +    L  P       
Sbjct: 5596 INKIVSDDSCTLLIQQGKRPDTGLYTLMASNSLG-----KASKEMRLNVLGRPGPPSAPI 5650

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSIN 1832
                I  E + ++W P + +GGS + +Y +  +   +K W             ++ L   
Sbjct: 5651 KFEEIGAERITLSWLPPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKERIWTVENLMTG 5710

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV-TLKWTEPES 1891
              Y FR+ A+N+ G   P  S+ ++     + P       V  +    +   ++     S
Sbjct: 5711 HEYVFRVMAQNKYGVGEPLDSEPEVARDLYIGPEVDLDTSVKEKMVVHAGGVIRIIAYVS 5770

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
               +P   +  +   +  ++  +   +  ++    I+    K   ++ ++A+N  G    
Sbjct: 5771 GQPTPDITWSRDGSALPPEAKVETTFISSAL---IIKPCSRKHLGVYTLTAKNAGG---- 5823

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
             + ++V +E    VP P   P     + ++    +W  PE DGG+P+  Y +  R+  + 
Sbjct: 5824 EKKKNVTVEV-LDVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIVEKREAERK 5882

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071
             W  V      T       L+   +Y  R+ A N IG+   +E+    +V+  E     E
Sbjct: 5883 AWTSVSFTASRT-NAVAHGLTSGKSYFFRVAAENAIGIGPFVET--AAEVVIREPISIPE 5939

Query: 2072 EPGEQTEV 2079
             P E+ EV
Sbjct: 5940 RP-EELEV 5946



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            DKPSPP    + E+ S S  + W  PE+ G + I +YVVE +++   +W+ V    K  +
Sbjct: 6378 DKPSPPRNLVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLS 6437

Query: 1439 SI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
             +   L     Y FR  A N+   SD   T    K +
Sbjct: 6438 LMAMYLMEGIQYLFRVAAENQFGRSDFIVTKTPVKAV 6474



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 10/135 (7%)

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEM-------NVTILDKPSPPGKPNILEIDSSSINI 1399
            +K V    AG Y L L N     +V++       N  + +KP PP +    +  S SI I
Sbjct: 4060 VKAVNKVGAGQY-LELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKSITI 4118

Query: 1400 CWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             W  P+N G   I  Y+VE   ++ D  E ++   +      +  LK N  Y+FR  A N
Sbjct: 4119 TWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVRAEN 4178

Query: 1458 EVDISDASETTEYYK 1472
               +S+ S +T+  K
Sbjct: 4179 VAGVSEPSRSTQLLK 4193



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 13/150 (8%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-----WIS---VKN 1432
            P+PP    +L+   S++ + W +P +TG + II YVVE +   + +     W        
Sbjct: 7292 PAPPSNLRVLDSTKSTVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQ 7351

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---K 1489
            +     ++ +L     Y FR  A N+V +S   +  +   VI +  +++P ++      +
Sbjct: 7352 LVVCDFTVTSLDDQLVYEFRVSAQNQVGMSLPCDLKD--AVIPKEILEAPEIDLDAMLKQ 7409

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
             +T      I L     G P PKVTW R G
Sbjct: 7410 GLTVRATCPIRLCATVRGRPPPKVTWRRMG 7439



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 7/121 (5%)

Query: 708  YTVVAVNREGEASLPIVLKIKT--GEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764
            + V+AVN  G        K  T   E EPP + ++    +I+R GES +L  +  G P P
Sbjct: 6010 FRVIAVNEVGPGKPSFCTKPITCKDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPP 6069

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            +I W ++++ VKA   +  K+   T S+ ++K ++ +  G Y +  ENS G  +    +T
Sbjct: 6070 SIAWYRDDEEVKADKHVMFKNTLTTMSLGLMKAQR-EHSGRYVVVVENSTGSRKGICNVT 6128

Query: 822  V 822
            V
Sbjct: 6129 V 6129



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 2/140 (1%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQK-LSINTTYQ 1836
            + +ES Y+TW   E NGG+ I  Y VE K    ++W          + +   L     Y 
Sbjct: 6391 VTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLMAMYLMEGIQYL 6450

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FR+ A N+ G S    +   +     L PP  P+N   +++    V L W  P+      
Sbjct: 6451 FRVAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHHTDADKTEVWLAWEWPDRTVPPT 6510

Query: 1897 ITNYIIEFKTVKGKSWTKIV 1916
            I   +   + V  K+ T IV
Sbjct: 6511 IEVDVKLIEGVIAKAGTTIV 6530



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 10/130 (7%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRN 859
            + +KA N  G  E S  IT +   +E A P + I +F     I +K+   I + A V   
Sbjct: 4766 FRVKAVNEVGDGEPSKAITAKIQDDELA-PVITILKFFKSNAIIIKKGSAIDIPAEVKGL 4824

Query: 860  PVPSITWYRNNEII-SPSETI----TQNFDGENIELVITNVDS-EIDSGDYKCVASNSAG 913
            P+PS+ W +++ +I +P E      T+  D   +   I   ++   D G+YK VA N  G
Sbjct: 4825 PLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFG 4884

Query: 914  KSSHGARVTI 923
            K+ H  RV I
Sbjct: 4885 KAQHVIRVEI 4894



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 7/128 (5%)

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
            V  +K+   PSPP   L +  V S     +W  PE +GGA +  Y +  +DV    W+ V
Sbjct: 6371 VSWKKNNDKPSPPRN-LVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPV 6429

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI-----PGEGSHADE 2071
               +   L      L E   Y+ R+ A N+ G S+ + +  P K +     PG   +   
Sbjct: 6430 SAAN-KKLSLMAMYLMEGIQYLFRVAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHH 6488

Query: 2072 EPGEQTEV 2079
               ++TEV
Sbjct: 6489 TDADKTEV 6496



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 3/121 (2%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + + A+N  G++  +      E  E+  EP + +   + ++ +    +++ A V   P P
Sbjct: 7633 FRVAAKNLMGLSLFTETREPVEIKEQMLEPTILMP--ESVSARAGAKLRVEAVVAGKPAP 7690

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
               W R  + + PS  +  +  G    L+I +V S  DSG+Y  VA NS+ K +   ++ 
Sbjct: 7691 MCKWMRGEDAVVPSSRLAVHQSGNLCVLIIKDV-SRTDSGEYSLVAENSSSKVTQALKIV 7749

Query: 923  I 923
            I
Sbjct: 7750 I 7750



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 16/141 (11%)

Query: 697  ITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPP-QVIEPLKS--MIVRQGES 751
            I N+ + QE  + V AVN   +GE S  I  KI+  E  P   +++  KS  +I+++G +
Sbjct: 4755 IENLSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELAPVITILKFFKSNAIIIKKGSA 4814

Query: 752  VILSAQVVGNPRPTITWCKNN----KPVK---ALPTKS-DGDTHSITILKPKKVK-DEGV 802
            + + A+V G P P++ W K++     PV+    + T+  D  T    I  P+ V+ D+G 
Sbjct: 4815 IDIPAEVKGLPLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGN 4874

Query: 803  YTLKAENSEGIAETSAVITVE 823
            Y L AEN  G A+   VI VE
Sbjct: 4875 YKLVAENCFGKAQ--HVIRVE 4893



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIE----PLKSMIVRQGESVILSAQVVGNPRPT 765
            VVA+N  G  +  +   +   E +   V+E      K +I+R GE + L A V G P+P 
Sbjct: 4475 VVAINDAGPGAPGVTEPVMVKEPQESPVVEFDASVKKGVIIRAGEPLKLPAVVTGRPQPE 4534

Query: 766  ITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            + W K+   +    +  +++G   S+ I K  +  D G Y +   NS G
Sbjct: 4535 VKWAKDEGEIDKDRMIVETEGKNSSLFIKKTTRT-DHGKYKISGTNSSG 4582



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 708  YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            + V   N  GE++     ++   E+  EP   I+   + +V+ G+S+ + A V G P+P 
Sbjct: 6968 FRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVVKAGDSIPIEAMVKGKPQPD 7027

Query: 766  ITWCKNN--KPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            + W K+N  + +K  P     +G   S  +L   +  D G Y +   NS G     A ++
Sbjct: 7028 VKWTKDNSTEEIKKGPRVQIENGTDFSKLLLTGARRTDSGKYVIAVTNSAGSCSAFATVS 7087

Query: 822  V 822
            V
Sbjct: 7088 V 7088



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 22/173 (12%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLF--KGEEIVPDENISVA-IESDMHMYCSVLKITNVKK 702
            ++G   ++   + A+  P  +W+      + VP E  +V  +E D+H    V+       
Sbjct: 7974 NDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQFRVI------- 8026

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVV 759
                  T V +++  E + P+++     E  PP++   +   K + V+ G +VIL A+V 
Sbjct: 8027 ----AKTAVNISKPSEPTDPVLV---CAENVPPRLDLNVRMQKGLKVKAGATVILEAEVF 8079

Query: 760  GNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDE-GVYTLKAENS 810
            G P P +TW + +  +K+   +      H   +      K+  GVYT+ AEN+
Sbjct: 8080 GKPMPRVTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKEHTGVYTILAENA 8132



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 3/84 (3%)

Query: 742  KSMIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798
            + + VR G++++++A  ++G P PT  W K  K  KA  L       T S   +K    K
Sbjct: 8933 EGLTVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRK 8992

Query: 799  DEGVYTLKAENSEGIAETSAVITV 822
            D G Y + A N  G+ E +  +TV
Sbjct: 8993 DTGEYVITASNPFGVKEETVKVTV 9016



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 9/110 (8%)

Query: 1358 YKLRLENNCGHADVEMNVTIL------DKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R EN  G ++   +  +L      DKP  P      EI ++S+   W+ PE+ G S 
Sbjct: 4172 FRVRAENVAGVSEPSRSTQLLKAADPVDKPGAPINFTFDEIRNTSVICNWEPPEDDGGSE 4231

Query: 1412 IIYYVVEYQEIDTTE--WISVKNITKTQT-SIQNLKTNSSYRFRAYAVNE 1458
            I+ Y++E ++    E  WI++ +  K  +  +  L     Y FR  A N+
Sbjct: 4232 ILNYILEKRDYKKEEVGWITITSTLKGNSFPVTKLIEGKEYIFRVTAENK 4281



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 26/212 (12%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXX 1535
            Q+P  + PL+ +T    E + L C   G P  KV W +D ++LK+++ T     +     
Sbjct: 4    QAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCL 63

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK----------------PVITISNED 1579
                        Y C A N  G       V +++K                PV  + N  
Sbjct: 64   EVEAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRRLDNLF 123

Query: 1580 IKQKHK---VGDEWLVT--AVIEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIK 1633
              ++ K     ++   T  A I G P P V W K    ++      +I  K + + + I+
Sbjct: 124  FIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDAKMEIR 183

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            E+ +S S  Y   ASN  G       ++V  K
Sbjct: 184  EVTKSDSGTYRCVASNKHGEIECSAEMEVTKK 215



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 59/278 (21%), Positives = 116/278 (41%), Gaps = 26/278 (9%)

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKV 797
            L+     + + ++LS ++  +    + W  + K + A  T   KS+G   S+ +LK  + 
Sbjct: 1095 LQDFAATEKDELLLSCEL--SKDVPVVWYHSEKEITASKTVVLKSEGTCRSL-LLKRVEQ 1151

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
              +G YT       G  +TSAV+ V+    +   P   +  F      +  T +    ++
Sbjct: 1152 SSKGTYTCDC----GTDKTSAVVDVQARDVKIVRPLYGVELF------DGETARFEVEIS 1201

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
             + V    W  N +++S S  +    DG    L++ N    + +G+    A+N+  K S 
Sbjct: 1202 EDDVRG-QWKLNGDVLSRSPDVDIIEDGSKHTLILYNCRVAM-AGEVAYTAANA--KCSA 1257

Query: 918  GARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREI 975
              +V  + +  +T +  +Q  YE +E +    E + S    S +W    +E+   +  E+
Sbjct: 1258 KLKVKELPLNFLTSLNDVQV-YEKDEAR---FEVELSRPPKSFRWLKGSQELQSDEKYEL 1313

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
            IQEG             D        +D+ T+  L+++
Sbjct: 1314 IQEGHTYVLLIRSAIYEDEAKYMFEAEDKRTACKLILQ 1351



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 10/169 (5%)

Query: 661  PEPDIAWLFKGEEIVPDENI--SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
            P P    +   E++ P++ +  +     D+ +  S LK +   KF+     ++ ++   E
Sbjct: 7589 PPPQPPVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTE 7648

Query: 719  ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PV 775
               P+ +K +  E   P ++ P +S+  R G  + + A V G P P   W +      P 
Sbjct: 7649 TREPVEIKEQMLE---PTILMP-ESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPS 7704

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
              L     G+   + I+K     D G Y+L AENS      +  I + +
Sbjct: 7705 SRLAVHQSGNL-CVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRD 7752



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ ++ E  V G P P   W R    + PS    ++    N+  L+I++V   D+G ++ 
Sbjct: 7675 GAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVH-QSGNLCVLIIKDVSRTDSGEYSL 7733

Query: 584  VAKNAAGFASSTTELIV 600
            VA+N++   +   ++++
Sbjct: 7734 VAENSSSKVTQALKIVI 7750



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 9/106 (8%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T ++QS AP  +E         GS +    ++ G P P +TW++     K     ++ YD
Sbjct: 5536 TIQDQSCAPS-IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPP-HKSDNKVEVQYD 5593

Query: 562  D-------DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +       D+  TL+I++    D G +T +A N+ G AS    L V
Sbjct: 5594 EHINKIVSDDSCTLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNV 5639



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 6/125 (4%)

Query: 704  QEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGESVILSAQVVG 760
            +E TY V A+N  GE A+  + +  K     P   +  L +M  I ++G +V L   + G
Sbjct: 8495 KEYTYRVKAINDSGEGAAKELTVVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISG 8554

Query: 761  NPRPTITWCK-NNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
             P P ++W K +++ +K            ++  +++  +  D   YT+   NS GI E++
Sbjct: 8555 KPIPKVSWKKGDDEDLKDSGRVCAESSSVNTTLLIRDCQRNDASKYTITLRNSAGIKEST 8614

Query: 818  AVITV 822
              I V
Sbjct: 8615 IFIRV 8619



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 4/125 (3%)

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEEN-AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            +Y  + +      E++ V T E   +E   EP + I       VK   +I + A V   P
Sbjct: 6965 IYQFRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVVKAGDSIPIEAMVKGKP 7024

Query: 861  VPSITWYRNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P + W ++N  E I     + Q  +G +   ++       DSG Y    +NSAG  S  
Sbjct: 7025 QPDVKWTKDNSTEEIKKGPRV-QIENGTDFSKLLLTGARRTDSGKYVIAVTNSAGSCSAF 7083

Query: 919  ARVTI 923
            A V++
Sbjct: 7084 ATVSV 7088



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449
            +I  +S  + W+ PE+ G S I  Y +E +E     ++ V +     T ++++L  N  Y
Sbjct: 3997 DITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLSGENVLTHTVKDLYVNCEY 4056

Query: 1450 RFRAYAVNEV 1459
             FR  AVN+V
Sbjct: 4057 FFRVKAVNKV 4066



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            + ++    +KL A VT  P P + W ++   I     I +  +G+N  L I    +  D 
Sbjct: 4513 VIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMIVET-EGKNSSLFIKKT-TRTDH 4570

Query: 902  GDYKCVASNSAGKSSHGARVTI 923
            G YK   +NS+G  S   RV I
Sbjct: 4571 GKYKISGTNSSGTKSAETRVDI 4592



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 11/135 (8%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVI--EPLKSMIVRQGE 750
            I N+    E    + AVNR G  S P+ +  K   K+    P  V+  E  + + +  G 
Sbjct: 8197 IQNLIDKNEYQCRITAVNRVG-FSEPVEVPGKHVAKDIIVAPEAVLSAELKEGLELNAGA 8255

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            ++ L A + G PRP ITW K N  +K    +  KS  +T +I +++     D G Y    
Sbjct: 8256 TMRLEATIKGRPRPKITWAKMNTNIKDRQGIVIKS-SNTDTIVMVENVNRYDAGKYIFNL 8314

Query: 808  ENSEGIAETSAVITV 822
            E+  G+   + V+ V
Sbjct: 8315 ESLAGMKMYTIVVKV 8329



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 9/155 (5%)

Query: 446  YILDTSNQDWWYVQKHLTEEKGW-VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSE 504
            Y+L+  N D  Y  K L   K     A+ L++   YT Y  K +N+  +         ++
Sbjct: 8464 YVLEVLNGDDKY--KELMRSKNMQYSAKDLVEGKEYT-YRVKAINDSGEGAAKELTVVAK 8520

Query: 505  EQSMAPIFVEKLRPKH---TPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYY 560
            +Q + P    +  P       +GSTV+ +  + G P P+++W +     +K S       
Sbjct: 8521 DQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDDEDLKDSGRVCAES 8580

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
               N  TL+IR+    DA  +T   +N+AG   ST
Sbjct: 8581 SSVNT-TLLIRDCQRNDASKYTITLRNSAGIKEST 8614



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 10/137 (7%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVL-KIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            K+ ++    E  + VVA N  G +        I   ++     IE  + M V QG  + +
Sbjct: 5503 KVEDLTYGDEYEFRVVAYNEAGPSRPSTTAGPITIQDQSCAPSIELQEFMEVEQGSDISI 5562

Query: 755  SAQVVGNPRPTITWCK--NNKPVKALPTKSD-------GDTHSITILKPKKVKDEGVYTL 805
             A++ G P PT+TW K   +K    +  + D        D     +++  K  D G+YTL
Sbjct: 5563 IAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSCTLLIQQGKRPDTGLYTL 5622

Query: 806  KAENSEGIAETSAVITV 822
             A NS G A     + V
Sbjct: 5623 MASNSLGKASKEMRLNV 5639



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%)

Query: 827  EENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
            ++  EPP     F++ I ++   +  L  R T  P PSI WYR++E +   + +      
Sbjct: 6033 KDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTL 6092

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              + L +     E  SG Y  V  NS G       VT+
Sbjct: 6093 TTMSLGLMKAQRE-HSGRYVVVVENSTGSRKGICNVTV 6129



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P+    L+   VN+G K + +  +     L V+W KD  E++ S   Q+T       L++
Sbjct: 6    PKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCLEV 65

Query: 1166 YDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPA 1210
                  +AG+Y C+  N+     C + ++V+E        +P   +VPA
Sbjct: 66   EAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFR---AVPAEAVVPA 111



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 10/108 (9%)

Query: 813  IAETSAVITV-EEPTE------ENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNPVPS 863
            IA+T+  I+   EPT+      EN  P L +N R Q+ + VK   T+ L A V   P+P 
Sbjct: 8026 IAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPR 8085

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
            +TW R +  +   E         + +L +T V  E  +G Y  +A N+
Sbjct: 8086 VTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKE-HTGVYTILAENA 8132



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 6/95 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
            PT   + +   V EG  + L+    AIP P + W     E   D+ +S+ +E +D H+  
Sbjct: 3853 PTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKVDDRLSMTLEMNDAHL-- 3910

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
             +LK T+      GTYT+V  N  G  +  + +K+
Sbjct: 3911 ELLKCTHA---DAGTYTIVLKNALGMVTGTVNVKV 3942



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 12/142 (8%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIF-VEKLRPKHT---PDGSTVQF 529
            + EN   Q+  K +NE  D  P        ++  +AP+  + K    +      GS +  
Sbjct: 4758 LSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELAPVITILKFFKSNAIIIKKGSAIDI 4817

Query: 530  ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV------ATLVIREVFPEDAGTFTC 583
              +V+G P P + W +   +I+   + +M  + + +        + I E   +D G +  
Sbjct: 4818 PAEVKGLPLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGNYKL 4877

Query: 584  VAKNAAGFASSTTEL-IVEAPL 604
            VA+N  G A     + I++ PL
Sbjct: 4878 VAENCFGKAQHVIRVEILDRPL 4899



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582
            G+T++ E  ++G PRP+ITW +    IK  Q   +     N  T+V +  V   DAG + 
Sbjct: 8254 GATMRLEATIKGRPRPKITWAKMNTNIKDRQG--IVIKSSNTDTIVMVENVNRYDAGKYI 8311

Query: 583  CVAKNAAGFASST 595
               ++ AG    T
Sbjct: 8312 FNLESLAGMKMYT 8324



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 24/105 (22%), Positives = 46/105 (43%)

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            T K+  +  +  P +    ++  +  G  + L V Y+A P P   W  ++   K      
Sbjct: 3841 TDKIFTKDPDSAPTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKVDDRLS 3900

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
             +++   A L + K  + DAG Y + L+N  G     +NV ++ +
Sbjct: 3901 MTLEMNDAHLELLKCTHADAGTYTIVLKNALGMVTGTVNVKVIGR 3945



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 1/108 (0%)

Query: 493  DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
            D   + +K  +++   AP    + +     +G  +  +   +  P P + W + T   K 
Sbjct: 3836 DPSEITDKIFTKDPDSAPTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKV 3895

Query: 553  SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                 M  +  N A L + +    DAGT+T V KNA G  + T  + V
Sbjct: 3896 DDRLSMTLEM-NDAHLELLKCTHADAGTYTIVLKNALGMVTGTVNVKV 3942



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 3/67 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  ++    V G P P ITW R  + + P    +  +     + L+I+    +  G +T 
Sbjct: 5760 GGVIRIIAYVSGQPTPDITWSRDGSALPPEAKVETTFIS---SALIIKPCSRKHLGVYTL 5816

Query: 584  VAKNAAG 590
             AKNA G
Sbjct: 5817 TAKNAGG 5823



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 6/117 (5%)

Query: 800  EGVYTLKAENS--EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            E  Y +KA N   EG A+   V+  ++    N +     N       KE  T++L   ++
Sbjct: 8496 EYTYRVKAINDSGEGAAKELTVVAKDQIIHPNCDLRELPNMCY--IAKEGSTVRLKIPIS 8553

Query: 858  RNPVPSITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
              P+P ++W + ++E +  S  +       N  L+I +     D+  Y     NSAG
Sbjct: 8554 GKPIPKVSWKKGDDEDLKDSGRVCAESSSVNTTLLIRDCQRN-DASKYTITLRNSAG 8609


>UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep:
            Projectin - Procambarus clarkii (Red swamp crayfish)
          Length = 8625

 Score =  245 bits (600), Expect = 9e-63
 Identities = 205/798 (25%), Positives = 314/798 (39%), Gaps = 39/798 (4%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            IK  + +   V  +  P+P   W VN   + + +        K   L I   + TD+G Y
Sbjct: 5282 IKVNTRLNYTVPIRGAPRPKVSWTVNGSPVVESERVDLQTYGKQTILDIPFAQRTDSGRY 5341

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             L LEN+ G       VT L   +  G  N+ ++   S  + +  P + G S I++Y+VE
Sbjct: 5342 TLTLENDLGKVSASGTVTSLTSLTAEGPLNVYDVTRESCKVSFKTPIDDGGSPILHYLVE 5401

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
              ++    W     +      +  L     Y FR  AVN +  S+    T+   + K  +
Sbjct: 5402 KMDVSRGTWTEAAEVAGLVAEVHGLVHMKEYHFRVKAVNAIGESEPL-CTDKSIIAKNAQ 5460

Query: 1479 IQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPKVTWYRDGKKLK------TAKATYE 1530
             +     +P        + D+E T     GG P   +T Y   KK +      TA     
Sbjct: 5461 DEPSPPGRPNVVDWDSDHVDMEWTPPAHDGGAP---ITGYLIQKKERGSPYWQTAARVSG 5517

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKHKV 1586
                             ++ IA N  G  E S     V+   +     I       + K 
Sbjct: 5518 PETKGTVPNLTEGQEYEFRIIAVNKAGNSEPSEPSDAVICRPRHLAPKILGPLYDVRIKA 5577

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G    V     G P P+V W+ +  +L+ D    IT     SV+      R+ S +Y I 
Sbjct: 5578 GQVLHVDVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHTVNTMRNDSGEYRIR 5637

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
              N +G       + V D P  PEGP++  E+   SV + WKPP+DDGG  +T Y IEK 
Sbjct: 5638 VKNESGQDEATFQVIVLDTPGAPEGPLVYEEVQANSVVMSWKPPVDDGGSPITGYVIEKR 5697

Query: 1707 E-PDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTA 1763
            +      W+   + VD       + +L E  +Y  RV A+N  G  E LES+ P+  K++
Sbjct: 5698 DISHGGGWVPAVNWVDPKQNHATVPRLLEGTQYDSRVRAENMQGRGEPLESDRPVTAKSS 5757

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXX 1822
             DVP            D + + I W P    GGSPI  Y VE       +WK        
Sbjct: 5758 ADVPGAPGRPSCTDS-DKDFIKIAWAPPRSTGGSPITGYDVERCGIHSGRWKKVNRDPVR 5816

Query: 1823 XARIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE--ST 1878
                   S+N    YQ+R+ A N++G S P      IT       P    + ++ +    
Sbjct: 5817 TTEFVDDSVNEGEQYQYRVVANNKMGPSNPSDPSQAITAKPMREAPKLYLDGLLGKKLKV 5876

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDE 1935
                 +    P S    P+  +  + K ++    T + T      +HC   ++  + +D 
Sbjct: 5877 RAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTS----DHCRLFVDKARREDS 5932

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              F I+AEN  G     + + + ++K    P PP  PL    V ++ V  SW  P+ +GG
Sbjct: 5933 GTFTITAENPYGKD-SADIEVIVVDK----PGPPIGPLTPTEVTAHTVSLSWKPPQDNGG 5987

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            A + GY   +   T T   E          F ++ L E   Y  R+ A N  G+SEPLE 
Sbjct: 5988 AEVTGY--VVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLEG 6045

Query: 2056 DEPFKVIPGEGSHADEEP 2073
                   P +   A + P
Sbjct: 6046 KPVEAKNPFDPPEAPDRP 6063



 Score =  227 bits (555), Expect = 3e-57
 Identities = 207/785 (26%), Positives = 332/785 (42%), Gaps = 47/785 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSK----IIKKCKHTKPS--IDSK--SASLTIKKV 1350
            IK G      +D    P+P + W +  K    I+ +   TK    +DS   +  L I K 
Sbjct: 3206 IKVGQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKA 3265

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409
            +   +G Y L   N  G   V++++TIL  PS P  P  + ++ ++   + WD+PE+ G 
Sbjct: 3266 QRKMSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKANGCKLKWDKPEDDGG 3325

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
              + +Y +E  +  T +W+        +  +  L+    Y+FR  AVN    S+  E  +
Sbjct: 3326 LPVDHYEIEKLDPITGQWMPCGESKTPEFDVTGLQEGKKYKFRVKAVNPEGESEPLEADK 3385

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNED-IELTCIF----GGVPQPK-VTWYRD--GKK 1521
               +I +     P+  KP K   T  + D +EL        GG    K +   RD  G+ 
Sbjct: 3386 --AIIAKNPFDPPS--KPGKPKATNWDRDFVELEWAKPKDDGGAEITKYIVEKRDVTGRG 3441

Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVIT---ISN 1577
                 +   NR               ++ +A N  G  E S     +  KP      I  
Sbjct: 3442 WTPCGSGPGNRTSIRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRFLAPRIDR 3501

Query: 1578 EDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
            + + +K  + G  +   + +EG P P+V W   G  ++N++   IT+++  + I I++ K
Sbjct: 3502 KSVGRKTIRSGITFKNESKVEGEPDPKVTWSLQGAPIKNER-VTITSEDHLTTIVIRKAK 3560

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            RS +  Y I A N +GT   E+ L V  KP KP+GP+ + +++ ES  ++W+PP DDGG 
Sbjct: 3561 RSDTGVYKIFAKNDSGTDEAELDLIVIGKPGKPKGPLKVSDVTAESAKLKWEPPEDDGGE 3620

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
             +  Y +E+ + +  RW+ V +         +  L E  +Y FRV A N  G SE LE++
Sbjct: 3621 PIDHYVVERMDTETGRWVPVKETKTPEAE--VPGLTEGKDYHFRVRAVNSEGESEPLETD 3678

Query: 1757 PIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK 1814
                 K   D PS           D     + W   E +GG+PI  Y +E K +   KW 
Sbjct: 3679 TATRAKNPYDPPS-KPGKPEVKDFDRTWCELKWKAPESDGGAPISHYVIERKDKYAAKWV 3737

Query: 1815 XXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                        ++  L+   TYQFR+ A N+ G S P  + D  T       P   R  
Sbjct: 3738 KHCDTKSDKPEFKVNDLTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTN 3797

Query: 1873 VVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIEN 1929
            + + +      +K+   + N  G PI          +  +    + +    H  +  I +
Sbjct: 3798 LENITVRAGQMIKF---DCNVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIAS 3854

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
                    F I A+NT G    T  + + L+K    P  P  PL++  +        W  
Sbjct: 3855 CTRAHNGTFVIKADNTAGHDEVT-IEVIVLDK----PGKPEGPLKVSDIHKEGCTLKWKE 3909

Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            P  DGGAP+  Y +   D     W+ VG+    T+   + +L   H Y  R+ A N  G 
Sbjct: 3910 PLDDGGAPIEQYIVEKMDTETGRWVPVGRSREPTMA--VENLEPMHEYKFRVSAINSEGE 3967

Query: 2050 SEPLE 2054
            SEPLE
Sbjct: 3968 SEPLE 3972



 Score =  221 bits (541), Expect = 1e-55
 Identities = 211/832 (25%), Positives = 324/832 (38%), Gaps = 43/832 (5%)

Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            L + +T  + V+    PPKI        R K G      V+    P P  +W++N K IK
Sbjct: 4661 LPSDATHPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIK 4720

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-N 1388
                T    +  +  L +       +G Y +  EN  G    ++ V +LDKP  P  P  
Sbjct: 4721 PSSVTNIRYNDYNTKLRVTGATREQSGTYTIVAENANGKDSADVEVIVLDKPGTPQGPLK 4780

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTN 1446
            + E+ +    + W  P + G   I +YVVE  +  T  W+        +T+  ++ L   
Sbjct: 4781 VSEVYAEGCKLDWKPPADDGGCPIDHYVVEQLDEATGRWVPAGETAGKETTFDVEGLTPG 4840

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--- 1503
              Y+FR  AVN +  SD   T +  +   +     P+  K + NI     + ++L     
Sbjct: 4841 HKYKFRVKAVNRLGTSDPLVTQQAIEA--KNPFDPPSSPKDV-NIADFDCDFVDLEWKKP 4897

Query: 1504 -IFGGVPQPKVTWYRDGKK-----LKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDH 1556
               GG P   +T Y   K+     L    AT + ++               ++ +A N  
Sbjct: 4898 ETDGGAP---ITGYIIEKRDRYNPLWDKCATVDGDQCKAHVPDLLEGNVYEFRVVAINKA 4954

Query: 1557 GEVETS-----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            G  E S      V   +  P     N  +  K K GD   +   + G PP    W    N
Sbjct: 4955 GPGEPSEPTKPHVARPKNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPATKQWRVRDN 5014

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
             L      +I  ++  + I+I + KRS S  +T+ A N  G  +  V + V D P  PEG
Sbjct: 5015 DLYPSDRLSIINEDYMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITVLDVPGAPEG 5074

Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731
            PV    I+R   +I WKPP DDGG E+T Y +EK + +  RW+   +V +D   + +  L
Sbjct: 5075 PVKFSNINRNGCSIAWKPPKDDGGSEITSYVVEKMDMETYRWVPCGEV-KDTH-FQVDNL 5132

Query: 1732 NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
             E  +Y FRV A N  G        + I  K     P+           D + V + W  
Sbjct: 5133 IEGHDYKFRVSAVNRQGQGPPCTGVDTITAKDPYSKPTKPGTPEVMDW-DKDRVDLQWTE 5191

Query: 1791 SEKNGGSPIIDYKVEIKQEGKKWKXXX---XXXXXXARIQKLSINTTYQFRIYARNEIGT 1847
               +GG+PI  + VE K+    W+            A +  L+    YQFR+ A N+ G 
Sbjct: 5192 PRSDGGAPITGWIVEKKKRFGPWEKALELPAKHGPKASVPDLTEGEEYQFRVIAVNKAGN 5251

Query: 1848 SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
            S P  S   +        P      +       +  L +T P      P  ++ +    V
Sbjct: 5252 SDPSDSSQPVVCKARFEKPGIDTKDLEDLIIKVNTRLNYTVPIRGAPRPKVSWTVNGSPV 5311

Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
                   + T G       I   +  D   + ++ EN +G    + S +V      T   
Sbjct: 5312 VESERVDLQTYGKQTILD-IPFAQRTDSGRYTLTLENDLG--KVSASGTVTSLTSLTA-- 5366

Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027
                PL +  V       S+ TP  DGG+P+L Y +   DV++  W E    +V  L   
Sbjct: 5367 --EGPLNVYDVTRESCKVSFKTPIDDGGSPILHYLVEKMDVSRGTWTEA--AEVAGLVAE 5422

Query: 2028 IRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
            +  L     Y  R+ A N IG SEPL +D+   +I          PG    V
Sbjct: 5423 VHGLVHMKEYHFRVKAVNAIGESEPLCTDK--SIIAKNAQDEPSPPGRPNVV 5472



 Score =  221 bits (539), Expect = 2e-55
 Identities = 187/764 (24%), Positives = 306/764 (40%), Gaps = 36/764 (4%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
            P P   W +N K  +        ID +     + I        G + ++ +N  GH +V 
Sbjct: 3819 PIPKKTWFIN-KARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHDEVT 3877

Query: 1373 MNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
            + V +LDKP  P  P  + +I      + W EP + G + I  Y+VE  + +T  W+ V 
Sbjct: 3878 IEVIVLDKPGKPEGPLKVSDIHKEGCTLKWKEPLDDGGAPIEQYIVEKMDTETGRWVPVG 3937

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
               +   +++NL+    Y+FR  A+N    S+  E  +   ++ +     P  + P K  
Sbjct: 3938 RSREPTMAVENLEPMHEYKFRVSAINSEGESEPLEGLD--TIVAKNPFDPP--DPPGKPE 3993

Query: 1492 TTEPNED-IELTCIF----GGVPQPKVTWYRDGKKLKTAKATYENRXXX---XXXXXXXX 1543
             T+ ++D +EL         G P    +       L +     E +              
Sbjct: 3994 ATDWDKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLREVKGDTPKGRVNDLDEG 4053

Query: 1544 XXXXYKCIAFNDHGEVETS-CVVGIQQKP---VITISNEDIKQKH-KVGDEWLVTAVIEG 1598
                ++  A N+ G  + S   + I  KP      I   +++    + G+  L+   + G
Sbjct: 4054 ETYEFRVRAVNEAGPSDPSEASLPITCKPRKLAPKIDRRNLRDLTVREGEPILLDVKVIG 4113

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             PPPEV W+     ++  K+  +      +     E  R HS    I A+N  G    E+
Sbjct: 4114 EPPPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVATNQHGRDEAEI 4173

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
            T+ V  KP KPEGP+ ++++ +E   ++WKPP DDGG  +  Y +EK +PD   W+ V  
Sbjct: 4174 TITVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYVVEKFDPDMGLWLPVGK 4233

Query: 1719 VDR-DVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXX 1776
                D+E   +  L    EY FRV A N  G SE L +  PI+ K    VP         
Sbjct: 4234 TSTPDME---VTDLTPGHEYEFRVKAVNKEGESEPLVTLSPILAKDPFTVPGKPGAPEAT 4290

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINT 1833
               D+  + + W    ++GG+ I  Y +E + +    W+          +     L    
Sbjct: 4291 DW-DSNHIDLKWSMPLEDGGAAISHYIIEKRDKYTNLWEKACETPTPECKGTATNLIEGM 4349

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
             YQFRI A N  G   P      I       PP   R  +   + S    LK+    S  
Sbjct: 4350 EYQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKYDCDISGE 4409

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
              P  ++  E + ++      I  +  +  +  I +    D   + I+A N+ G    T 
Sbjct: 4410 PPPTASWTYEGRKLEASRHVTIANIDYN-SKLVIRDTVRADSGEYVITATNSSGKDQVTV 4468

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
              +V        PSPP  P+++  V        W  P+ DGG P+  Y +   D    +W
Sbjct: 4469 RVTV-----TDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLW 4523

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            +  G+         + +LS    Y  R+ A N  G S+PL ++E
Sbjct: 4524 VPAGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEE 4567



 Score =  220 bits (537), Expect = 4e-55
 Identities = 187/786 (23%), Positives = 325/786 (41%), Gaps = 35/786 (4%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++  IK G +V   ++ +  P P+ +W++  + +K       ++D  +    +   +   
Sbjct: 2612 KQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNT-KFNMIDAKRKQ 2670

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTII 1413
             G YK+   N  G  +  + + +L  P  P  P  + ++   S  + WD+P++ G   I 
Sbjct: 2671 TGTYKIIATNRDGKDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCKLKWDKPDDDGGKPIQ 2730

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             Y+VE Q+  T  W+ V         +  L+    Y FR  A+N+   S+  ET ++  +
Sbjct: 2731 EYLVEKQDPTTGRWVPVGRTKDLAMDVPGLQEGKEYNFRVKAINDEGESEPLET-DHSTL 2789

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVPQPKVTWYRDGKKLK--TAKA 1527
             K+     P  +  + +I     + ++L        GG P   +T Y   KK +  T + 
Sbjct: 2790 AKDP--YGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAP---ITKYIIEKKERYGTWET 2844

Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKPVITISNE 1578
             +E+   +               ++ +A N  G  + S             KP+I  + E
Sbjct: 2845 IHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLI--NRE 2902

Query: 1579 DIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
             +K+   +   +  +   ++G PPPE+ W     K+E    Y I  ++  +   + + +R
Sbjct: 2903 KLKKITTRASQKVFLEVDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAER 2962

Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
             H+  Y I A N +G+   E+ + V D+P KPEGP+ + ++ +E   ++W+ P DDGGL 
Sbjct: 2963 RHTGIYKIHAKNDSGSDEAELEIIVLDRPGKPEGPLEISDVHKEGCKLKWEKPKDDGGLP 3022

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE- 1756
            +T Y  EK +  + +W+     D D     +  L    +Y FRV A N  G S+ L+ + 
Sbjct: 3023 ITGYVAEKMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDEGESDPLDGDR 3082

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815
             I+ K   D P            D  SV + W P  ++GG+ I  Y +E+K +    +  
Sbjct: 3083 AIIAKDPFDKPG-PPGLPEIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVE 3141

Query: 1816 XXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                     +  I  L     Y+FR+ A N+ G   P  S    T       P   R  V
Sbjct: 3142 VGKVKGNVCQGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTARAKFRKPRIDRTNV 3201

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
                        +         P   + ++ K +      ++VT      +    N K  
Sbjct: 3202 KDVVIKVGQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLL 3261

Query: 1934 -DEIIFRISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
              +   ++S +  +  +      SV+++      PS P  PLE+  V +N     W  PE
Sbjct: 3262 IMKAQRKMSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKANGCKLKWDKPE 3321

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             DGG P+  Y I   D     WM  G  +  T +F++  L E   Y  R+ A N  G SE
Sbjct: 3322 DDGGLPVDHYEIEKLDPITGQWMPCG--ESKTPEFDVTGLQEGKKYKFRVKAVNPEGESE 3379

Query: 2052 PLESDE 2057
            PLE+D+
Sbjct: 3380 PLEADK 3385



 Score =  215 bits (524), Expect = 1e-53
 Identities = 190/789 (24%), Positives = 316/789 (40%), Gaps = 46/789 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            IK G      VDY   P P+  W     ++                ++I      DAG+Y
Sbjct: 2308 IKVGRSHKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLY 2367

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             L++EN  G     + + +L KPS P  P  +  +  +   + W++P++ G   I  Y V
Sbjct: 2368 TLKIENRNGQDSETVELVVLGKPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEV 2427

Query: 1418 EYQEIDTTEWISVKN----ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            E  ++ T +W+        +     +++ L+    Y+FR  AVN  D  D+        +
Sbjct: 2428 EKMDLATGKWVRCGKCPGALAPPYFNVEGLEPGHQYKFRVTAVN--DEGDSDPLEADGAI 2485

Query: 1474 IKETKIQSPTVE-KPLKNITTEPNEDIELTCIF----GGVPQPKVTWYRDGKKLKTAKAT 1528
            + +     PT   +P   I    N+ ++L        GG P  K    +  K +   +  
Sbjct: 2486 LAKNPYDVPTAPGRP--EIVDYDNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVA 2543

Query: 1529 YENRXX------------XXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVI 1573
             E +                           ++ +A N  G   E E +    ++ K + 
Sbjct: 2544 AELKQDVIQPLKPGTPVETKVGGLKHRAEYQFRVVAVNKAGNSPESEPTDYHLVKHKALK 2603

Query: 1574 T-ISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
              I    +KQ   K G        IEG PPP V W     +++ D    I   +  +   
Sbjct: 2604 PRIDRTHLKQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVK-DSNIEIVNVDYNTKFN 2662

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            + + KR  +  Y I A+N  G     V + V   P KP+GP+ + +++++S  ++W  P 
Sbjct: 2663 MIDAKRKQTGTYKIIATNRDGKDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCKLKWDKPD 2722

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            DDGG  + +Y +EK +P   RW+ V    +D+    +  L E  EY FRV A N  G SE
Sbjct: 2723 DDGGKPIQEYLVEKQDPTTGRWVPVGRT-KDL-AMDVPGLQEGKEYNFRVKAINDEGESE 2780

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
             LE++   +      P            D + V + W   +  GG+PI  Y +E K+   
Sbjct: 2781 PLETDHSTLAKDPYGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAPITKYIIEKKERYG 2840

Query: 1812 KWKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
             W+            R+  L    TYQFR+ A N+ G   P +   K  + K        
Sbjct: 2841 TWETIHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDP-SDPTKPHLAKARFLKPLI 2899

Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSP--ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
                + + T+R+    + E +  G  P  I   +   K   G ++  ++     + +  +
Sbjct: 2900 NREKLKKITTRASQKVFLEVDVKGEPPPEIWWTLKNKKVETGPNY--VIQAEDYLTKFTL 2957

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
             + + +   I++I A+N  G S   E + + L++    P  P  PLEI  V        W
Sbjct: 2958 NDAERRHTGIYKIHAKNDSG-SDEAELEIIVLDR----PGKPEGPLEISDVHKEGCKLKW 3012

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              P+ DGG P+ GY     DVT   W+  G+ D +     +  L     Y  R+ A N+ 
Sbjct: 3013 EKPKDDGGLPITGYVAEKMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDE 3072

Query: 2048 GLSEPLESD 2056
            G S+PL+ D
Sbjct: 3073 GESDPLDGD 3081



 Score =  213 bits (519), Expect = 6e-53
 Identities = 185/713 (25%), Positives = 294/713 (41%), Gaps = 53/713 (7%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-- 1436
            DKP PPG P I++ D +S+ + WD P   G + I  YV+E +  +   ++ V  +     
Sbjct: 3091 DKPGPPGLPEIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVEVGKVKGNVC 3150

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495
            Q  I  LK    Y FR  AVN+  + + S++T  +      K + P +++  +K++  + 
Sbjct: 3151 QGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTA--RAKFRKPRIDRTNVKDVVIKV 3208

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA------------TYENRXXXXXXXXXXX 1543
             +         G P+P  TW    K L +               +  N            
Sbjct: 3209 GQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKAQRK 3268

Query: 1544 XXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                Y   A N+HGE        ++G   KP   +   D+K  +    +W       G+P
Sbjct: 3269 MSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKA-NGCKLKWDKPEDDGGLP 3327

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS----- 1655
               V  Y+         ++    + KT    +  L+     K+ ++A N  G S      
Sbjct: 3328 ---VDHYEIEKLDPITGQWMPCGESKTPEFDVTGLQEGKKYKFRVKAVNPEGESEPLEAD 3384

Query: 1656 -VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
               +    +D PSKP  P       R+ V +EW  P DDGG E+TKY +EK +     W 
Sbjct: 3385 KAIIAKNPFDPPSKPGKPKATNW-DRDFVELEWAKPKDDGGAEITKYIVEKRDVTGRGWT 3443

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXX 1773
                   +  +  I  +  + EY+FRV+A+N  G SE  + S+ ++ K     P      
Sbjct: 3444 PCGSGPGNRTSIRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRFLAPRIDRKS 3503

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-----IQK 1828
                 I +    IT+    K  G P  D KV    +G   K                I+K
Sbjct: 3504 VGRKTIRSG---ITFKNESKVEGEP--DPKVTWSLQGAPIKNERVTITSEDHLTTIVIRK 3558

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWT 1887
               + T  ++I+A+N+ GT       D I IGK    P +P+    VS+ T+ S  LKW 
Sbjct: 3559 AKRSDTGVYKIFAKNDSGTD--EAELDLIVIGK----PGKPKGPLKVSDVTAESAKLKWE 3612

Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
             PE +GG PI +Y++E    +   W  +        E  +  + E  +  FR+ A N+ G
Sbjct: 3613 PPEDDGGEPIDHYVVERMDTETGRWVPVKET--KTPEAEVPGLTEGKDYHFRVRAVNSEG 3670

Query: 1948 VSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
             S P E+ +    K+    PS P  P E++          W  PE DGGAP+  Y I  +
Sbjct: 3671 ESEPLETDTATRAKNPYDPPSKPGKP-EVKDFDRTWCELKWKAPESDGGAPISHYVIERK 3729

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
            D     W++      +  +F + DL+E  TY  R+ A N+ G S+P ++ + F
Sbjct: 3730 DKYAAKWVKHCDTKSDKPEFKVNDLTEGETYQFRVKAVNKAGQSKPSDASDNF 3782



 Score =  212 bits (517), Expect = 1e-52
 Identities = 158/603 (26%), Positives = 265/603 (43%), Gaps = 29/603 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQT 1438
            PSPPG P + +I  + +++ W  PE+ G S I  Y++E +E+ +  W+     NI  TQ 
Sbjct: 6852 PSPPGTPVVTKIGKNYVDLKWSVPESDGGSRITGYMIEKRELGSI-WMKCNDYNIVDTQY 6910

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            ++ NL   S   FR YA+N    SD S++ +  K+ +    + P   K L+N     ++ 
Sbjct: 6911 TVLNLTEGSEVEFRVYAINAAGKSDPSQSAQPVKIREAAPGEKPFFVKNLQNTAVALHKS 6970

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTA-KATYEN---RXXXXXXXXXXXXXXXYKCIAFN 1554
            + L C   G P P   W R+G+++    + T E    +               Y C+A N
Sbjct: 6971 VTLECEAEGKPTPTARWLRNGREVTLGGRITSEESKGKFKLFISDMWEVDEGDYACVAAN 7030

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            D G+  +   V I   P IT   + +      GD   +     G  P +V   +NG  +E
Sbjct: 7031 DAGQATSIAHVKIGNPPRITQMQDALYLPE--GDNTKIKIYFTGDLPLDVTLSQNGLPVE 7088

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
              +    T  ++  +I I+E+ +  + +YT+   N +G+ +    + +   P  P  P+ 
Sbjct: 7089 ESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVKNDSGSVTGNFIVYITGVPGAPTAPLD 7148

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
            + +ISR    + W+PP+ DGGL +T Y +E+ +     WI +    +D  ++ +Q L E 
Sbjct: 7149 VTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWITINSFCKDC-SFTVQGLTEG 7207

Query: 1735 CEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
             EY+FRV+A N  G    L    PI  K   D PS          +  + V++ W     
Sbjct: 7208 QEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPS-PPGTPNVTEVGGDFVHLEWDKPAH 7266

Query: 1794 NGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLP 1850
            +GGS I  Y VE ++ G   W           +I    L  +  Y+FR++A N+ G S P
Sbjct: 7267 DGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGMSEP 7326

Query: 1851 YTSDDKITI--GKTLTPP---SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
             T    + I      TPP   +  RN +  +  S ++T +        G P  N I  FK
Sbjct: 7327 STCSTSVRIKDPNAATPPEIITPLRNVMALQHRSATLTCQ------IAGKPRPN-ISWFK 7379

Query: 1906 TVKG--KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
             ++    S    +   G  +   + ++  +DE  +   A+N+ G+       S++L    
Sbjct: 7380 GMRELCNSAKYAMNRDGDTYTLTVHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKI 7439

Query: 1964 TVP 1966
             VP
Sbjct: 7440 NVP 7442



 Score =  209 bits (511), Expect = 6e-52
 Identities = 130/389 (33%), Positives = 195/389 (50%), Gaps = 10/389 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            G+E+ +T      P P+V W+   N++  +N  ++++ +   ++V   K  KRS   KYT
Sbjct: 6569 GEEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYT 6628

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            I+ +N+ G  S    + V D+PS P+GP+ + +I+ ++ ++ W+PPLDDGG  +T Y +E
Sbjct: 6629 IKLTNSEGADSGSCKVNVVDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVE 6688

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763
            + EP    W+KV+   R    Y +  L  N  YMFRV A+N  G S+ LE+ +PI  K  
Sbjct: 6689 RLEPVTGMWVKVSAFVRSCH-YDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFP 6747

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXX--XXXX 1820
              VP            D  SV +TW     +GGS I  YKVE +      W         
Sbjct: 6748 FTVPDPPGRPNILDH-DINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVK 6806

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                 +  L IN  Y+FR+ A+N  G S       KI +    + PS P   VV++    
Sbjct: 6807 ETTYTVHSLLINHEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPSPPGTPVVTKIGKN 6866

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
             V LKW+ PES+GGS IT Y+IE K   G  W K         ++ + N+ E  E+ FR+
Sbjct: 6867 YVDLKWSVPESDGGSRITGYMIE-KRELGSIWMKCNDYNIVDTQYTVLNLTEGSEVEFRV 6925

Query: 1941 SAENTVGVSLPTES-QSVRLEKHATVPSP 1968
             A N  G S P++S Q V++ + A    P
Sbjct: 6926 YAINAAGKSDPSQSAQPVKIREAAPGEKP 6954



 Score =  204 bits (497), Expect = 3e-50
 Identities = 163/687 (23%), Positives = 294/687 (42%), Gaps = 38/687 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  +  LQN  V      T E E   K     RW ++G E+     I  T +  K K K+
Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRI--TSEESKGKFKL 7011

Query: 1166 YDCDL--DDAGEYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
            +  D+   D G+Y+C   N   + T+I  V+  +     ++ + + +P   +  + +   
Sbjct: 7012 FISDMWEVDEGDYACVAANDAGQATSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFT 7071

Query: 1222 -DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT 1277
             D  LDVT  +    +E+++  KFT+  +     + IR+  + D  +YT  +  D+ S T
Sbjct: 7072 GDLPLDVTLSQNGLPVEESQRLKFTVFDEFI--IIFIREVVKQDAGQYTLTVKNDSGSVT 7129

Query: 1278 KLKVEVVEFPPKIVDYEREYR-IKRGS-DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
               +  +   P       +   I R   ++           P   ++V  K I       
Sbjct: 7130 GNFIVYITGVPGAPTAPLDVTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWIT 7189

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------DKPSPPGKPNI 1389
             +   K  S T++ +      ++++   N  G       V  +      D PSPPG PN+
Sbjct: 7190 INSFCKDCSFTVQGLTEGQEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPSPPGTPNV 7249

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNS 1447
             E+    +++ WD+P + G S I  Y VE +EI +  W  V       TQ ++ NL  + 
Sbjct: 7250 TEVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDR 7309

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
             Y FR +A N+  +S+ S  +   ++        P +  PL+N+    +    LTC   G
Sbjct: 7310 QYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRNVMALQHRSATLTCQIAG 7369

Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX----YKCIAFNDHGEVETSC 1563
             P+P ++W++  ++L  +     NR                   Y C A N  G   T  
Sbjct: 7370 KPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGEDEDEYMCRAQNSGGIRSTKA 7429

Query: 1564 VVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
             + I+  P I +     D     K G+  ++     G P P + W + G  +E+   Y++
Sbjct: 7430 DISIKLAPKINVPPRFRDTAFFDK-GENAVIKIPFIGNPRPRITWQREGETIESGGHYSV 7488

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
             T+++ +++ ++++    +  Y + A N  G+ SV + +++ D+P  P  P +   +  E
Sbjct: 7489 ETQQRHAILHLRDVTNLDTGNYRLTAENELGSDSVIIKIQISDRPDPPRLPKVESILGTE 7548

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
             V + W+ PL DGG  +  Y IEK E     WI+ ++    + T  I+ L+   +Y FRV
Sbjct: 7549 CV-LTWQIPLWDGGANINNYIIEKRELPMESWIRCSNT--RLTTAQIKGLSPGHKYQFRV 7605

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPS 1768
             A+N  G      S+P  + + ++ P+
Sbjct: 7606 YAENVYG-----RSDPSAVTSVVETPA 7627



 Score =  188 bits (458), Expect = 1e-45
 Identities = 126/465 (27%), Positives = 198/465 (42%), Gaps = 10/465 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G PPP   W   G KLE  +   I   +  S + I++  R+ S +Y I A+N++G   
Sbjct: 4406 ISGEPPPTASWTYEGRKLEASRHVTIANIDYNSKLVIRDTVRADSGEYVITATNSSGKDQ 4465

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            V V + V DKPS PEGP+ + ++      ++WK P DDGG  +  Y +EK +P+   W+ 
Sbjct: 4466 VTVRVTVTDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLWVP 4525

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXX 1774
                     +  +  L+   EY FRV A N  G S+ L +E  V+ K   + P       
Sbjct: 4526 AGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPENLK 4585

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXARIQKLSIN 1832
                 D   V + W P + +GG+PI  Y VE K +   W              +  L   
Sbjct: 4586 VADY-DQNKVDLKWEPPKSDGGAPIQKYIVEKKDKYGGWDKACEVPANKTSCSVPDLIEG 4644

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
             TY+FR+ A N  G  LP  +   +T+     PP   R  ++   +    +  +    S 
Sbjct: 4645 ETYEFRVRAVNPAGPGLPSDATHPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSG 4704

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
               P   +++  K +K  S T I     +         +E+    + I AEN  G     
Sbjct: 4705 EPVPEKKWLLNKKDIKPSSVTNIRYNDYNTKLRVTGATREQSG-TYTIVAENANGKD-SA 4762

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
            + + + L+K    P  P  PL++  V +      W  P  DGG P+  Y +   D     
Sbjct: 4763 DVEVIVLDK----PGTPQGPLKVSEVYAEGCKLDWKPPADDGGCPIDHYVVEQLDEATGR 4818

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            W+  G+       F++  L+  H Y  R+ A N +G S+PL + +
Sbjct: 4819 WVPAGETAGKETTFDVEGLTPGHKYKFRVKAVNRLGTSDPLVTQQ 4863



 Score =  186 bits (452), Expect = 8e-45
 Identities = 176/718 (24%), Positives = 284/718 (39%), Gaps = 45/718 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS- 1439
            P PP  P    I  + + + W  P   G + I  Y+VEY++ D  EW    ++    T+ 
Sbjct: 6157 PGPPDAPRPDRIGRNCVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNY 6216

Query: 1440 -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNE 1497
             +  L     Y FR  AVNEV  S  S  +   K+  E +   P ++   +++      E
Sbjct: 6217 TVLGLTELEEYYFRVIAVNEVGPSAPSRPSALIKI--EEQANKPRIDLSAVRDPPVRAGE 6274

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA------KATYENRXXXXXXXXXXXXXXXYKCI 1551
            D  +   + G P+P  TWY D + +         +   ++                YK  
Sbjct: 6275 DFSIHVPYTGFPKPTSTWYHDDEDINIGADPRIHEKLTDDYCAMIVTNAQRSDTGPYKLR 6334

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW-LVTAVIEGIPPPEVIWYKNG 1610
              N  G    S  V +  +P      E+++     GD   L     +     E+  Y   
Sbjct: 6335 LQNPSGFDSVSLNVRVLDRPA---PPENLRADEFNGDALTLFWNPPKDNGGAEITNYVVE 6391

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLK-VYD 1664
             +        +++      +RI+ L  ++   + + A N  G     TS+  +  +  +D
Sbjct: 6392 KREGRGNWTKVSSYVTAPFLRIRNLVVNNEYDFRVMAENQYGQSDPCTSANPIRARHPFD 6451

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             P  P  P  + E + +S+TI+W  P  DGG  +  Y +EK    +N W K +       
Sbjct: 6452 PPGAPGAPRGL-ESTEDSITIQWSKPRHDGGSHIQGYVVEKRIVGDNTWTKASHAMVKDT 6510

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVG---FSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            TY +  L E+ EY FRV A N  G   +S+  E+   +   A  + S             
Sbjct: 6511 TYRVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCISFRAPKITSDLSIRDMTVIAGE 6570

Query: 1782 ESVYITWFPSEKNGGSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTY-QF 1837
            E      F +      P + + +   E+  + +              + K +  +   ++
Sbjct: 6571 EFTITVPFIASPQ---PKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKY 6627

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
             I   N  G     +   K+ +    +PP  P    VS+ T  + +L W  P  +GGSPI
Sbjct: 6628 TIKLTNSEGAD---SGSCKVNVVDRPSPPQGPLE--VSDITPDTCSLAWRPPLDDGGSPI 6682

Query: 1898 TNYIIE-FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            TNY +E  + V G  W K+     S H + +  ++     +FR+ AEN  G+S P E+  
Sbjct: 6683 TNYQVERLEPVTGM-WVKVSAFVRSCH-YDVMGLEPNRSYMFRVRAENQYGLSDPLETLD 6740

Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
                K   TVP PP  P  I     N V+ +W  P  DGG+ + GY +  RDVT T W  
Sbjct: 6741 PITAKFPFTVPDPPGRP-NILDHDINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAA 6799

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
                 V    + +  L  NH Y  R+ A+N  G S   +   P K I  +G ++   P
Sbjct: 6800 ANDFLVKETTYTVHSLLINHEYEFRVKAKNAAGFS---KYSPPSKKIKMKGKYSVPSP 6854



 Score =  183 bits (445), Expect = 5e-44
 Identities = 206/876 (23%), Positives = 351/876 (40%), Gaps = 61/876 (6%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
            DVTW + ++V+ +T++  + +      + I   T  D   YT  + +        VE+V 
Sbjct: 2327 DVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLKIENRNGQDSETVELVV 2386

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ----PNDEWIVNSKIIKKCKHTKPSIDSK 1341
               K    +    +    D    + ++        P  E+ V    +   K  +      
Sbjct: 2387 LG-KPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEVEKMDLATGKWVRCGKCPG 2445

Query: 1342 SASLTIKKVENTDAGI-YKLRLE--NNCGHAD-VEMNVTIL-----DKPSPPGKPNILEI 1392
            + +     VE  + G  YK R+   N+ G +D +E +  IL     D P+ PG+P I++ 
Sbjct: 2446 ALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEADGAILAKNPYDVPTAPGRPEIVDY 2505

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-----------TKTQTSIQ 1441
            D+ S+++ W  PE+ G + I+ Y+V+ ++    +W     +           T  +T + 
Sbjct: 2506 DNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVAAELKQDVIQPLKPGTPVETKVG 2565

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIE 1500
             LK  + Y+FR  AVN+   S  SE T+Y+ V  + K   P +++  LK  T +   +++
Sbjct: 2566 GLKHRAEYQFRVVAVNKAGNSPESEPTDYHLV--KHKALKPRIDRTHLKQTTIKAGRNVK 2623

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHG 1557
                  G P P V W    +++K +     N                   YK IA N  G
Sbjct: 2624 FDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNTKFNMIDAKRKQTGTYKIIATNRDG 2683

Query: 1558 EVETSCVVGIQQ---KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            + E +  + +     KP   +   D+ +K     +W       G P  E +  K      
Sbjct: 2684 KDEAAVEIVVLSGPGKPKGPLKVSDVTKK-SCKLKWDKPDDDGGKPIQEYLVEKQD---P 2739

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEV---TLKV--YDKPSK 1668
                +    + K   + +  L+      + ++A N  G S  +E    TL    Y  P K
Sbjct: 2740 TTGRWVPVGRTKDLAMDVPGLQEGKEYNFRVKAINDEGESEPLETDHSTLAKDPYGPPGK 2799

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P  P I+ +   + V ++W+ P D GG  +TKY IEK E     W  + + +       +
Sbjct: 2800 PGIPDIV-DWDVDRVDLKWEAPKDTGGAPITKYIIEKKERYGT-WETIHESEGPKTECRV 2857

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYI 1786
              L E   Y FRV+A N  G  +  + ++P + K     P              ++ V++
Sbjct: 2858 PGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLINREKLKKITTRASQKVFL 2917

Query: 1787 TWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
                  K    P I + ++ K  + G  +            +       T  ++I+A+N+
Sbjct: 2918 E--VDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAERRHTGIYKIHAKND 2975

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
             G+     ++ +I +   L  P +P     +S+       LKW +P+ +GG PIT Y+ E
Sbjct: 2976 SGSD---EAELEIIV---LDRPGKPEGPLEISDVHKEGCKLKWEKPKDDGGLPITGYVAE 3029

Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
               V    W       G   +  +  ++   +  FR+ A N  G S P +     + K  
Sbjct: 3030 KMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDEGESDPLDGDRAIIAKDP 3089

Query: 1964 -TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
               P PP  P EI     N V   W  P  DGGA + GY + ++      ++EVGKV  N
Sbjct: 3090 FDKPGPPGLP-EIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVEVGKVKGN 3148

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              +  I  L E   Y  R+ A N+ GL EP +S  P
Sbjct: 3149 VCQGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLP 3184



 Score =  183 bits (445), Expect = 5e-44
 Identities = 114/392 (29%), Positives = 176/392 (44%), Gaps = 12/392 (3%)

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
            K K + G+   +   + G P P   W K G KLE  K  ++ T      + + + +R  S
Sbjct: 5873 KLKVRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARREDS 5932

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
              +TI A N  G  S ++ + V DKP  P GP+   E++  +V++ WKPP D+GG E+T 
Sbjct: 5933 GTFTITAENPYGKDSADIEVIVVDKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAEVTG 5992

Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760
            Y +E+  P            +    + ++ L E  +Y FRV A+N  G SE LE +P+  
Sbjct: 5993 YVVERPTPTTTYERSCQGTAK--PNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKPVEA 6050

Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX 1820
            K   D P               +  + W P    GG PI  Y +E ++ G  W       
Sbjct: 6051 KNPFD-PPEAPDRPDIVDYSPSTCSLEWKPPTDTGGRPITGYIIEKRERGGDWIRVNHYP 6109

Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT--IGKTLT-PPSQPRNFVVS 1875
                +  +Q LS    Y+FRI A NE G   P    + I   + K L  PP  PR   + 
Sbjct: 6110 TPNTQYTVQGLSEGNRYEFRIIALNEAGPGKPSKPSNSIVAKVPKYLPGPPDAPRPDRIG 6169

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
             +    VTL W  P  +GG+ I  Y++E++      W    ++      + +  + E +E
Sbjct: 6170 RN---CVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNYTVLGLTELEE 6226

Query: 1936 IIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
              FR+ A N VG S P+  S  +++E+ A  P
Sbjct: 6227 YYFRVIAVNEVGPSAPSRPSALIKIEEQANKP 6258



 Score =  180 bits (438), Expect = 4e-43
 Identities = 198/865 (22%), Positives = 356/865 (41%), Gaps = 56/865 (6%)

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF 1286
            W KK   +E +++ ++ +      L + K   +D   +T    +   K +  ++V VV+ 
Sbjct: 5898 WSKKGKKLEPSKRTSMETTSDHCRLFVDKARREDSGTFTITAENPYGKDSADIEVIVVDK 5957

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSIDSKS 1342
            P   +       +      T+ + ++  PQ N    V   ++++   T    +    +  
Sbjct: 5958 PGPPIGPLTPTEVTAH---TVSLSWKP-PQDNGGAEVTGYVVERPTPTTTYERSCQGTAK 6013

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-----LDKPSPPGKPNILEIDSSSI 1397
             + T+K +E      +++R EN  G ++      +      D P  P +P+I++   S+ 
Sbjct: 6014 PNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKPVEAKNPFDPPEAPDRPDIVDYSPSTC 6073

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
            ++ W  P +TG   I  Y++E +E    +WI V +     TQ ++Q L   + Y FR  A
Sbjct: 6074 SLEWKPPTDTGGRPITGYIIEKRE-RGGDWIRVNHYPTPNTQYTVQGLSEGNRYEFRIIA 6132

Query: 1456 VNEVDISDASETTEYYKVIKETKI-----QSPTVEKPLKNITT----EPNEDIELTCIFG 1506
            +NE      S+ +    V K  K       +P  ++  +N  T     P++D     I G
Sbjct: 6133 LNEAGPGKPSKPSNSI-VAKVPKYLPGPPDAPRPDRIGRNCVTLSWRPPSQDGGAK-IRG 6190

Query: 1507 GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---EVETSC 1563
             + + +    +D  + + A +                    ++ IA N+ G       S 
Sbjct: 6191 YLVEYR---QKDEDEWQPANSLPHPDTNYTVLGLTELEEYYFRVIAVNEVGPSAPSRPSA 6247

Query: 1564 VVGIQQ---KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
            ++ I++   KP I +S        + G+++ +     G P P   WY +   +    +  
Sbjct: 6248 LIKIEEQANKPRIDLSAVR-DPPVRAGEDFSIHVPYTGFPKPTSTWYHDDEDINIGADPR 6306

Query: 1621 ITTK--EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
            I  K  +    + +   +RS +  Y +   N +G  SV + ++V D+P+ PE  +   E 
Sbjct: 6307 IHEKLTDDYCAMIVTNAQRSDTGPYKLRLQNPSGFDSVSLNVRVLDRPAPPEN-LRADEF 6365

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            + +++T+ W PP D+GG E+T Y +EK E   N W KV+          I+ L  N EY 
Sbjct: 6366 NGDALTLFWNPPKDNGGAEITNYVVEKREGRGN-WTKVSSY-VTAPFLRIRNLVVNNEYD 6423

Query: 1739 FRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
            FRV+A+N  G S+   S  PI  +   D P            + +S+ I W     +GGS
Sbjct: 6424 FRVMAENQYGQSDPCTSANPIRARHPFDPPGAPGAPRGLESTE-DSITIQWSKPRHDGGS 6482

Query: 1798 PIIDYKVEIKQEG-KKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
             I  Y VE +  G   W             R+  L+ +  Y+FR+ A N  G   P++  
Sbjct: 6483 HIQGYVVEKRIVGDNTWTKASHAMVKDTTYRVINLTEHQEYEFRVAAINAAGQG-PWSDP 6541

Query: 1855 DKITIGKTLTPPSQPRNFVVSEST-SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
             +     +   P    +  + + T         T P      P   + I    V   +  
Sbjct: 6542 SENIKCISFRAPKITSDLSIRDMTVIAGEEFTITVPFIASPQPKVQWWIGPNEVIPDNRV 6601

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973
            +   +  S +     N   K   I + + + T      + S  V +      PSPP  PL
Sbjct: 6602 QF-HMDSSNNSTVFVNKSAKRSDIGKYTIKLTNSEGADSGSCKVNVVDR---PSPPQGPL 6657

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033
            E+  +  +    +W  P  DGG+P+  Y +   +    MW++V    V +  +++  L  
Sbjct: 6658 EVSDITPDTCSLAWRPPLDDGGSPITNYQVERLEPVTGMWVKVSAF-VRSCHYDVMGLEP 6716

Query: 2034 NHTYMIRIYARNEIGLSEPLESDEP 2058
            N +YM R+ A N+ GLS+PLE+ +P
Sbjct: 6717 NRSYMFRVRAENQYGLSDPLETLDP 6741



 Score =  180 bits (437), Expect = 5e-43
 Identities = 141/478 (29%), Positives = 203/478 (42%), Gaps = 28/478 (5%)

Query: 1598 GIPPPEVIWYKNGNKLENDKE------YNITTKEKTSV----IRIKELKRSHSSKYTIEA 1647
            G P P VIW K+  ++  D+E      YN      +S     +  +E +     +    A
Sbjct: 2014 GEPEPRVIWKKDDKEVIPDEEQRLPEPYNCRRSPSSSSRGHSLHAEEGRSLRHRQVQASA 2073

Query: 1648 SNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
             +T   S   E  + V  KP++PEGP+   EI  + VT++WK PLDDGGL +  Y IEK 
Sbjct: 2074 RSTLWASVKEEADVVVLGKPTRPEGPLFPEEIRADHVTLKWKKPLDDGGLPIEGYVIEKM 2133

Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALD 1765
            + D   WI   +V  + + + +  L    +Y FRV A N  G SE LE+ EPI+ +   D
Sbjct: 2134 DMDTGAWIPAGEVGPEKQEFTVDGLTPKKKYKFRVKAVNKEGESEPLENDEPILARNPYD 2193

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX-- 1822
             PS           DN  V + W P E +GG PI  Y +E+K +    WK          
Sbjct: 2194 EPS-RPGKPEIIDYDNTMVVLRWTPPESDGGRPITHYHIEMKDKLSVDWKEVVQTKDTNC 2252

Query: 1823 XARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNF-VVSESTSR 1880
             A++  L   T Y FR+ A N+ G       +D+ +   K   P     NF  V+    R
Sbjct: 2253 EAQVPGLKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGR 2312

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
            S   KW         P   +      +       I        E  I +   KD  ++ +
Sbjct: 2313 S--HKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHT-EISITDATRKDAGLYTL 2369

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
              EN  G     +S++V L      PS P  PLE+  V        W  P+ DGG P+  
Sbjct: 2370 KIENRNG----QDSETVELVVLGK-PSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKE 2424

Query: 2001 YNIAIRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
            Y +   D+    W+  GK    +    FN+  L   H Y  R+ A N+ G S+PLE+D
Sbjct: 2425 YEVEKMDLATGKWVRCGKCPGALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEAD 2482



 Score =  177 bits (431), Expect = 3e-42
 Identities = 140/476 (29%), Positives = 211/476 (44%), Gaps = 32/476 (6%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P+  W+ N  + +ND+    I  ++  + I I    R+H+  + I+A NTAG  
Sbjct: 3815 VTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHD 3874

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
             V + + V DKP KPEGP+ + +I +E  T++WK PLDDGG  + +Y +EK + +  RW+
Sbjct: 3875 EVTIEVIVLDKPGKPEGPLKVSDIHKEGCTLKWKEPLDDGGAPIEQYIVEKMDTETGRWV 3934

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXX 1773
             V    R+  T  ++ L    EY FRV A N  G SE LE  + IV K   D P      
Sbjct: 3935 PVGR-SRE-PTMAVENLEPMHEYKFRVSAINSEGESEPLEGLDTIVAKNPFDPPDPPGKP 3992

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKV----EIKQEGKKWKXXXXXXXXXARIQKL 1829
                  D + V + W    K+ G+P +   +         G + +          R+  L
Sbjct: 3993 EATDW-DKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLR-EVKGDTPKGRVNDL 4050

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITI-GKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
                TY+FR+ A NE G S P  +   IT   + L P    RN        R +T++  E
Sbjct: 4051 DEGETYEFRVRAVNEAGPSDPSEASLPITCKPRKLAPKIDRRNL-------RDLTVREGE 4103

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            P       I     E +   GK   K         +  +EN+    + I         GV
Sbjct: 4104 PILLDVKVIGEPPPEVEWFHGKKPIK------ETKDLRVENVPYNTKYINDEPLRKHSGV 4157

Query: 1949 S-LPTESQSVRLEKHATV-----PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
            + +   +Q  R E   T+     P  P  P+E++ V        W  P+ DGG+P+ GY 
Sbjct: 4158 TKIVATNQHGRDEAEITITVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYV 4217

Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
            +   D    +W+ VGK   +T    + DL+  H Y  R+ A N+ G SEPL +  P
Sbjct: 4218 VEKFDPDMGLWLPVGK--TSTPDMEVTDLTPGHEYEFRVKAVNKEGESEPLVTLSP 4271



 Score =  173 bits (422), Expect = 3e-41
 Identities = 207/871 (23%), Positives = 335/871 (38%), Gaps = 56/871 (6%)

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-- 1284
            TW+  K+  ++ +    I +   RT ++I  CT      +     +     ++ +EV+  
Sbjct: 3824 TWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHDEVTIEVIVL 3883

Query: 1285 ------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
                  E P K+ D  +E    +  +   L D  A   P +++IV  K+  +     P  
Sbjct: 3884 DKPGKPEGPLKVSDIHKEGCTLKWKEP--LDDGGA---PIEQYIVE-KMDTETGRWVPVG 3937

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEI 1392
             S+  ++ ++ +E      +++   N+ G ++ +E   TI+     D P PPGKP   + 
Sbjct: 3938 RSREPTMAVENLEPMHEYKFRVSAINSEGESEPLEGLDTIVAKNPFDPPDPPGKPEATDW 3997

Query: 1393 DSSSINICWDEP-ENTGNSTIIYYV--VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
            D   + + W +P ++ G  ++   +  V       +    VK  T  +  + +L    +Y
Sbjct: 3998 DKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLREVKGDT-PKGRVNDLDEGETY 4056

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             FR  AVNE   SD SE +      K  K+      + L+++T    E I L     G P
Sbjct: 4057 EFRVRAVNEAGPSDPSEAS-LPITCKPRKLAPKIDRRNLRDLTVREGEPILLDVKVIGEP 4115

Query: 1510 QPKVTWYRDGKKLKTAK-ATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P+V W+   K +K  K    EN                    K +A N HG  E    +
Sbjct: 4116 PPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVATNQHGRDEAEITI 4175

Query: 1566 GIQQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             +  KP       ++K  HK G   +W       G P    +      K + D    +  
Sbjct: 4176 TVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYV----VEKFDPDMGLWLPV 4231

Query: 1624 -KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMR 1676
             K  T  + + +L   H  ++ ++A N  G S   VTL        +  P KP  P    
Sbjct: 4232 GKTSTPDMEVTDLTPGHEYEFRVKAVNKEGESEPLVTLSPILAKDPFTVPGKPGAPE-AT 4290

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
            +     + ++W  PL+DGG  ++ Y IEK +   N W K  +            L E  E
Sbjct: 4291 DWDSNHIDLKWSMPLEDGGAAISHYIIEKRDKYTNLWEKACETPTPECKGTATNLIEGME 4350

Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            Y FR+ A N  G  E  + S+ I+ K     P           I   S  +  +  + +G
Sbjct: 4351 YQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGS--MLKYDCDISG 4408

Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSD 1854
              P          EG+K +              KL I  T   R  +   + T+   +  
Sbjct: 4409 EPP---PTASWTYEGRKLEASRHVTIANIDYNSKLVIRDT--VRADSGEYVITATNSSGK 4463

Query: 1855 DKITIGKTLT-PPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
            D++T+  T+T  PS P   + VS+       LKW  P+ +GG+PI  Y +E        W
Sbjct: 4464 DQVTVRVTVTDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLW 4523

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
                   G      + N+    E  FR+ A N  G S P  ++   L K           
Sbjct: 4524 VPAGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPEN 4583

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
            L++     N V   W  P+ DGGAP+  Y +  +D     W +  +V  N    ++ DL 
Sbjct: 4584 LKVADYDQNKVDLKWEPPKSDGGAPIQKYIVEKKD-KYGGWDKACEVPANKTSCSVPDLI 4642

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            E  TY  R+ A N  G   P ++  P  V P
Sbjct: 4643 EGETYEFRVRAVNPAGPGLPSDATHPVTVKP 4673



 Score =  162 bits (393), Expect = 1e-37
 Identities = 175/732 (23%), Positives = 301/732 (41%), Gaps = 51/732 (6%)

Query: 1358 YKLRLENNCGHAD---VEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTGNST 1411
            +++R  N  G +D    E +V   D    PGKP  L++   D + +++ W+ P++ G + 
Sbjct: 4549 FRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPENLKVADYDQNKVDLKWEPPKSDGGAP 4608

Query: 1412 IIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            I  Y+VE ++     W     +   KT  S+ +L    +Y FR  AVN       S+ T 
Sbjct: 4609 IQKYIVEKKD-KYGGWDKACEVPANKTSCSVPDLIEGETYEFRVRAVNPAGPGLPSDAT- 4666

Query: 1470 YYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
             + V  + K   P +++  L  + ++  +         G P P+  W  + K +K +  T
Sbjct: 4667 -HPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVT 4725

Query: 1529 ---YEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584
               Y +                 Y  +A N +G+      V +  KP        + + +
Sbjct: 4726 NIRYNDYNTKLRVTGATREQSGTYTIVAENANGKDSADVEVIVLDKPGTPQGPLKVSEVY 4785

Query: 1585 KVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
              G   +W   A   G P    +  +             T  ++T+   ++ L   H  K
Sbjct: 4786 AEGCKLDWKPPADDGGCPIDHYVVEQLDEATGRWVPAGETAGKETT-FDVEGLTPGHKYK 4844

Query: 1643 YTIEASNTAGTSSVEVTLKV------YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            + ++A N  GTS   VT +       +D PS P+  V + +   + V +EWK P  DGG 
Sbjct: 4845 FRVKAVNRLGTSDPLVTQQAIEAKNPFDPPSSPK-DVNIADFDCDFVDLEWKKPETDGGA 4903

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
             +T Y IEK +  N  W K A VD D     +  L E   Y FRV+A N  G  E  E  
Sbjct: 4904 PITGYIIEKRDRYNPLWDKCATVDGDQCKAHVPDLLEGNVYEFRVVAINKAGPGEPSEPT 4963

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
               +    ++P           ID  ++      +  N   P+    V      K+W+  
Sbjct: 4964 KPHVARPKNLPP---------RIDRNAMMDVKVKAGDNLNLPV--PVVGEPPATKQWRVR 5012

Query: 1817 XXXXXXXARIQKLSIN--TTYQFRIYARNEIG----TSLPYTSDDKITIGKT-LTPPSQP 1869
                    R+  ++ +  TT +     R++ G     +     +D  T+  T L  P  P
Sbjct: 5013 DNDLYPSDRLSIINEDYMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITVLDVPGAP 5072

Query: 1870 RNFVVSESTSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
               V   + +R+  ++ W  P+ +GGS IT+Y++E   ++   W     V  +  +  ++
Sbjct: 5073 EGPVKFSNINRNGCSIAWKPPKDDGGSEITSYVVEKMDMETYRWVPCGEVKDTHFQ--VD 5130

Query: 1929 NIKEKDEIIFRISAENTVGVSLP-TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
            N+ E  +  FR+SA N  G   P T   ++  +   + P+ P  P E+     + V   W
Sbjct: 5131 NLIEGHDYKFRVSAVNRQGQGPPCTGVDTITAKDPYSKPTKPGTP-EVMDWDKDRVDLQW 5189

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV-NTLKFNIRDLSENHTYMIRIYARNE 2046
              P  DGGAP+ G+ I  +      W +  ++   +  K ++ DL+E   Y  R+ A N+
Sbjct: 5190 TEPRSDGGAPITGW-IVEKKKRFGPWEKALELPAKHGPKASVPDLTEGEEYQFRVIAVNK 5248

Query: 2047 IGLSEPLESDEP 2058
             G S+P +S +P
Sbjct: 5249 AGNSDPSDSSQP 5260



 Score =  160 bits (389), Expect = 3e-37
 Identities = 172/715 (24%), Positives = 281/715 (39%), Gaps = 55/715 (7%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKT 1436
            D+PS PGKP I++ D++ + + W  PE+ G   I +Y +E ++  + +W  V     T  
Sbjct: 2193 DEPSRPGKPEIIDYDNTMVVLRWTPPESDGGRPITHYHIEMKDKLSVDWKEVVQTKDTNC 2252

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495
            +  +  LK  + Y FR  A N+  I +ASE T+ +  + + K + P +++   K++T + 
Sbjct: 2253 EAQVPGLKEGTVYSFRVKAANKAGIGEASEPTDNH--LCKHKNRKPRIDRTNFKSVTIKV 2310

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCI 1551
                +    + G P P VTW R    L  T +   EN                   Y   
Sbjct: 2311 GRSHKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLK 2370

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYK- 1608
              N +G+   +  + +  KP       ++   H  G   +W       G+P  E    K 
Sbjct: 2371 IENRNGQDSETVELVVLGKPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEVEKM 2430

Query: 1609 ---NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVT 1659
                G  +   K              ++ L+  H  K+ + A N  G S         + 
Sbjct: 2431 DLATGKWVRCGK---CPGALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEADGAILA 2487

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
               YD P+ P  P I+ +   +SV ++W  P  DGG  + KY ++K +     W   A++
Sbjct: 2488 KNPYDVPTAPGRPEIV-DYDNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVAAEL 2546

Query: 1720 DRD----------VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI---VIKTALDV 1766
             +D          VET  +  L    EY FRV+A N  G S   ESEP    ++K     
Sbjct: 2547 KQDVIQPLKPGTPVETK-VGGLKHRAEYQFRVVAVNKAGNSP--ESEPTDYHLVKHKALK 2603

Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826
            P           I  ++     F     G  P     V  +QE K             + 
Sbjct: 2604 PRIDRTHLKQTTI--KAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNTKF 2661

Query: 1827 QKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVT 1883
              +      T  ++I A N  G       D+       L+ P +P+    VS+ T +S  
Sbjct: 2662 NMIDAKRKQTGTYKIIATNRDG------KDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCK 2715

Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
            LKW +P+ +GG PI  Y++E +      W  +        +  +  ++E  E  FR+ A 
Sbjct: 2716 LKWDKPDDDGGKPIQEYLVEKQDPTTGRWVPVGRTKDLAMD--VPGLQEGKEYNFRVKAI 2773

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            N  G S P E+    L K    P       +I     + V   W  P+  GGAP+  Y I
Sbjct: 2774 NDEGESEPLETDHSTLAKDPYGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAPITKYII 2833

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
              ++   T W  + + +    +  +  L E +TY  R+ A N+ G  +P +  +P
Sbjct: 2834 EKKERYGT-WETIHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKP 2887



 Score =  155 bits (375), Expect = 2e-35
 Identities = 151/643 (23%), Positives = 281/643 (43%), Gaps = 64/643 (9%)

Query: 499  EKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            E+P   +Q   +AP F +K   K    G  ++FEC++   PRP ITWFR    ++ S   
Sbjct: 106  EQPVDIKQIDGLAPTFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARC 165

Query: 557  QMYYDDDN---VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            ++  + D      T+    V  EDAG +   AKN  G +++T  L  ++      S M +
Sbjct: 166  KVTTEKDEKSYFVTMAFTNVTVEDAGKYKVTAKNELGESNATISLNFDS------SFMML 219

Query: 614  XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                            EG+ PTF+++P  +  ++G+ ++  CR VA P+P I W FKG++
Sbjct: 220  TADEVPSPK-------EGVRPTFTERPSIKQSEDGTSVIFSCRCVANPQPTIVWEFKGKK 272

Query: 674  IVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTG 730
            +       + +E D  +Y  V L++  V    EG Y  VA N+  EG A++ +  + KT 
Sbjct: 273  LREGARHRMKLEPDGKLYYMVILEVNKVTNADEGEYRAVASNKLGEGVATINLHFEGKTA 332

Query: 731  EKEPPQVIE------PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALP 779
              + P++ +      P K  I ++G+ +++   +  NP P +TW K  + ++     ++ 
Sbjct: 333  -SDKPKIPDGKAPRFPKKPEIRQEGDKLVMECILEANPEPEVTWFKGTEIIQEQGRISMY 391

Query: 780  TKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLF 835
             K  G      S+TI+KP +  D G +   A N  G +  +  +  E+         P F
Sbjct: 392  KKICGKDQFIVSVTIMKP-EASDGGQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTF 450

Query: 836  INRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETIT---QNFDGENIEL- 890
            +++   I   E GT I +  R    P P++ W+++ + +  ++ +         E  E  
Sbjct: 451  LDK-PSIIPNESGTMITMKVRCKAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYS 509

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYETEEGK 944
             I       D+G YKCVA N  G+++    + I+       +   FV+     +E + G+
Sbjct: 510  CIVKDPCGADAGKYKCVAMNQFGEATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGR 569

Query: 945  TVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX----XDVGVIK 998
             V++E   +     +++W  + KE+        + + +                D GV K
Sbjct: 570  -VLMEALVRADPKPTSRWTKDGKELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYK 628

Query: 999  CIVKDQ--ETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEI 1055
            C +K++  E +  L +  E  P   R  +   V  + V I  V I++      W +D   
Sbjct: 629  CNIKNEFGELNANLNLNIEVAPTIKRPPRIVSVFNRKVVIECVVISTSKPACSWFKDSSK 688

Query: 1056 IK-PKKNKYDFEKRG---HIRKLYIRNTSVHDEGEYSCILRDE 1094
            ++   ++  +  + G   ++ ++ +      D G Y  + ++E
Sbjct: 689  VRLDTRHCVNINEEGEGKYVVQMEMLKAEKMDCGSYKVVAKNE 731



 Score =  147 bits (355), Expect = 4e-33
 Identities = 180/750 (24%), Positives = 318/750 (42%), Gaps = 93/750 (12%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--- 563
            + AP F +K + +   DG+ + F+C++   P+P I WFR+   +K S   ++        
Sbjct: 4    NFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGKGG 63

Query: 564  NV--ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
            N+    L++ +V  EDAG +   AKN  G  S++  L          +E  V        
Sbjct: 64   NIHDVQLILDDVEEEDAGLYKVKAKNKYGEVSASINLNFSP------NEQPVDIKQ---- 113

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                   ++G+ PTF++KP  +  + G  I  ECR++A P P I W   G ++       
Sbjct: 114  -------IDGLAPTFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCK 166

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK------IKTGEK--E 733
            V  E D   Y   +  TNV     G Y V A N  GE++  I L       + T ++   
Sbjct: 167  VTTEKDEKSYFVTMAFTNVTVEDAGKYKVTAKNELGESNATISLNFDSSFMMLTADEVPS 226

Query: 734  PPQVIEP--LKSMIVRQ---GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783
            P + + P   +   ++Q   G SVI S + V NP+PTI W    K ++      +  + D
Sbjct: 227  PKEGVRPTFTERPSIKQSEDGTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPD 286

Query: 784  GDTHSITILKPKKV--KDEGVYTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRF 839
            G  + + IL+  KV   DEG Y   A N   EG+A  +     +  +++   P     RF
Sbjct: 287  GKLYYMVILEVNKVTNADEGEYRAVASNKLGEGVATINLHFEGKTASDKPKIPDGKAPRF 346

Query: 840  -QEITVKEKGTIKLVAR--VTRNPVPSITWYRNNEIISPSETIT--QNFDGENIELV-IT 893
             ++  ++++G  KLV    +  NP P +TW++  EII     I+  +   G++  +V +T
Sbjct: 347  PKKPEIRQEGD-KLVMECILEANPEPEVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVT 405

Query: 894  NVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH------LQK-SYETEEGKT 945
             +  E  D G ++C A N  G S+  A + ++ EK   +        L K S    E  T
Sbjct: 406  IMKPEASDGGQWRCNAFNPFGDSN--ANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGT 463

Query: 946  VI---LECQTSHTVSTKWYHNKKEISG-----MDHREIIQEGRXXXXXXXXXXXXDVGVI 997
            +I   + C+     + +W+ + K++       +   ++  E              D G  
Sbjct: 464  MITMKVRCKAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKY 523

Query: 998  KCIVKDQ---ETSTMLVVKETIPE-------FIRK-LQDFEVKEKDVAILEVEINSETAD 1046
            KC+  +Q    T+ + +  E+ PE       F+ K    FE K   V ++E  + ++   
Sbjct: 524  KCVAMNQFGEATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGRV-LMEALVRADPKP 582

Query: 1047 VV-WERDGEIIKPKK--NKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDE--SCTAEV 1100
               W +DG+ +   +       EK    R ++ +R     D G Y C +++E     A +
Sbjct: 583  TSRWTKDGKELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANL 642

Query: 1101 TV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTID 1157
             + +E+ P I    +   V         + ++       WFKD S+++      + +  +
Sbjct: 643  NLNIEVAPTIKRPPRIVSVFNRKVVIECVVISTSKPACSWFKDSSKVRLDTRHCVNINEE 702

Query: 1158 GKKQ---KLKIYDCDLDDAGEYSCEVGNSK 1184
            G+ +   ++++   +  D G Y     N K
Sbjct: 703  GEGKYVVQMEMLKAEKMDCGSYKVVAKNEK 732



 Score =  146 bits (353), Expect = 8e-33
 Identities = 90/308 (29%), Positives = 145/308 (47%), Gaps = 8/308 (2%)

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW-KXXXXXXX 1821
            +D PS          I  ++  + W P   +GGSPI +Y+VE ++     W K       
Sbjct: 6647 VDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVERLEPVTGMWVKVSAFVRS 6706

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                +  L  N +Y FR+ A N+ G S P  + D IT     T P  P    + +    S
Sbjct: 6707 CHYDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFPFTVPDPPGRPNILDHDINS 6766

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
            V L W  P S+GGS I  Y +E++ V   +W            + + ++    E  FR+ 
Sbjct: 6767 VVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVKETTYTVHSLLINHEYEFRVK 6826

Query: 1942 AENTVGVS-LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            A+N  G S     S+ ++++   +VPSPP  P+ +  +G N V   W  PE DGG+ + G
Sbjct: 6827 AKNAAGFSKYSPPSKKIKMKGKYSVPSPPGTPV-VTKIGKNYVDLKWSVPESDGGSRITG 6885

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            Y I  R++  ++WM+    ++   ++ + +L+E      R+YA N  G S+P +S +P K
Sbjct: 6886 YMIEKRELG-SIWMKCNDYNIVDTQYTVLNLTEGSEVEFRVYAINAAGKSDPSQSAQPVK 6944

Query: 2061 V---IPGE 2065
            +    PGE
Sbjct: 6945 IREAAPGE 6952



 Score =  141 bits (342), Expect = 2e-31
 Identities = 206/878 (23%), Positives = 338/878 (38%), Gaps = 76/878 (8%)

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288
            W+ KK  +    K+   S+    TL+I K T DD  +YT   +    +  L V+  +   
Sbjct: 1336 WFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKYTVECMGIACSCILTVQEPDPDF 1395

Query: 1289 KIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLT 1346
            K V    ++       D TL     +  +    W    + I++ +  +   D + +  LT
Sbjct: 1396 KFVRPLPKKISSYTTKDATLEAQVNSH-KAIVHWFKGEEKIEEDEKFETYKDMTGTVRLT 1454

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            IK     D G Y  ++   C     E  ++I+D+P    K    ++ S ++       EN
Sbjct: 1455 IKNASKKDKGKYTAKIFR-CEKEFTETLLSIVDQPFKFTK----QLKSKTVT------EN 1503

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            +    I+   V+  E +   +   + +T     ++ +K     +    +++  D  + S 
Sbjct: 1504 S--KVILECDVDEAEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSISMDDAGNYSC 1561

Query: 1467 TTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
             T   +   E  +Q     +K L++  T   +           P   + W+ +GK++ T 
Sbjct: 1562 RTNADETTCEIIVQYENKFKKKLQDQMTYERQPATFEVELVD-PNAPLQWFINGKEV-TE 1619

Query: 1526 KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQQKPVITISNEDIKQ 1582
               YE  +               ++       G +ET+C   VG  +KP      E I+ 
Sbjct: 1620 GDNYEFQKKGGVHRLIIKEAATAHEGEIKAVCGNLETACQLSVGEGEKPPSIKPEEPIEG 1679

Query: 1583 KHKVGDEWLVTAVIEG--IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
                   + V   I G  I   +    K+G  + N KE  +   +K  +   K+  R  S
Sbjct: 1680 PVTKPLVFEVPYTIPGARISKVDAKLLKDGKPM-NVKEVEVNILDKKVIYTFKKPSRDQS 1738

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
             KYTI  SN AG SS EV + + D+PS P   V + EI   S  I + PP DDGGL LT 
Sbjct: 1739 GKYTIRMSNKAGESSKEVKINMQDRPSPPTN-VEVSEIFSTSCLITFGPPKDDGGLPLTY 1797

Query: 1701 YAIEKHE-----------PDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVG 1748
            Y IE+ +                W +VA++  D    +  + L    +Y F+V   N +G
Sbjct: 1798 YIIERQDFSVKASHPRIWERTGGWAQVAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLG 1857

Query: 1749 FSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
             S+  +  + I+ K   D P              +   + W   E +GG+PI  Y +E +
Sbjct: 1858 PSDPFIHPKVILAKDPWDEPGKILHVEVNDW-GPDHADLRWSRPETDGGAPITGYVIEFR 1916

Query: 1808 QEGKKWKXXXXXXXXXAR------------IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
                            A+            I  L     Y+FR+ A N+ G   P     
Sbjct: 1917 TRAMPGAGEVDRFSDWAKGIEIQGDVTEGTIPDLKEGNQYEFRVRAVNKAGPGEPSDPTK 1976

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE----PESNGGSPITNYI---------- 1901
             I        P     FV+++   +++ +K T+        GG P    I          
Sbjct: 1977 PIQAKHRFVKP-----FVINKDEFKNIVIKKTQLFKLDVKYGGEPEPRVIWKKDDKEVIP 2031

Query: 1902 -IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
              E +  +  +  +  +     H    E  +       + SA +T+  S+  E+  V L 
Sbjct: 2032 DEEQRLPEPYNCRRSPSSSSRGHSLHAEEGRSLRHRQVQASARSTLWASVKEEADVVVLG 2091

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
            K  T P  P  P EIR   ++ V   W  P  DGG P+ GY I   D+    W+  G+V 
Sbjct: 2092 K-PTRPEGPLFPEEIR---ADHVTLKWKKPLDDGGLPIEGYVIEKMDMDTGAWIPAGEVG 2147

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                +F +  L+    Y  R+ A N+ G SEPLE+DEP
Sbjct: 2148 PEKQEFTVDGLTPKKKYKFRVKAVNKEGESEPLENDEP 2185



 Score =  139 bits (336), Expect = 9e-31
 Identities = 128/535 (23%), Positives = 229/535 (42%), Gaps = 39/535 (7%)

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018
            KW+  K E+      +   EG             D+G           S +L V+E  P+
Sbjct: 1335 KWFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKYTVECMGIACSCILTVQEPDPD 1394

Query: 1019 FI------RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            F       +K+  +  K+   A LE ++NS  A V W +  E I+  +    ++      
Sbjct: 1395 FKFVRPLPKKISSYTTKD---ATLEAQVNSHKAIVHWFKGEEKIEEDEKFETYKDMTGTV 1451

Query: 1073 KLYIRNTSVHDEGEYSC-ILRDESCTAE--VTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
            +L I+N S  D+G+Y+  I R E    E  +++V+ P +   +L+++ V + +K   E +
Sbjct: 1452 RLTIKNASKKDKGKYTAKIFRCEKEFTETLLSIVDQPFKFTKQLKSKTVTENSKVILECD 1511

Query: 1130 LTKGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
            + + +A V WF  G ++   + I ++  DGKK++L      +DDAG YSC     + T  
Sbjct: 1512 VDEAEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSISMDDAGNYSCRTNADETTCE 1571

Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248
            + V+  +  F  +L + +       A   VE+ D    + W+     + + + +      
Sbjct: 1572 IIVQYEN-KFKKKLQDQMTYERQP-ATFEVELVDPNAPLQWFINGKEVTEGDNYEFQKKG 1629

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
                LII++     + E   V  + ++  +L V   E PP I   + E  I+ G     L
Sbjct: 1630 GVHRLIIKEAATAHEGEIKAVCGNLETACQLSVGEGEKPPSI---KPEEPIE-GPVTKPL 1685

Query: 1309 VDYQAFPQPNDEWI-VNSKIIK-----KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
            V    +  P      V++K++K       K  + +I  K    T KK     +G Y +R+
Sbjct: 1686 VFEVPYTIPGARISKVDAKLLKDGKPMNVKEVEVNILDKKVIYTFKKPSRDQSGKYTIRM 1745

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
             N  G +  E+ + + D+PSPP    + EI S+S  I +  P++ G   + YY++E Q+ 
Sbjct: 1746 SNKAGESSKEVKINMQDRPSPPTNVEVSEIFSTSCLITFGPPKDDGGLPLTYYIIERQDF 1805

Query: 1423 D-----------TTEWISVKNITKTQT---SIQNLKTNSSYRFRAYAVNEVDISD 1463
                        T  W  V  I   +      ++L+    Y+F+    N++  SD
Sbjct: 1806 SVKASHPRIWERTGGWAQVAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLGPSD 1860



 Score =  129 bits (311), Expect = 9e-28
 Identities = 87/325 (26%), Positives = 138/325 (42%), Gaps = 10/325 (3%)

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            F + A+NP G  ++ + E IV+    D P           +   +V ++W P + NGG+ 
Sbjct: 5935 FTITAENPYG-KDSADIEVIVV----DKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAE 5989

Query: 1799 IIDYKVEIKQEGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
            +  Y VE       ++            ++ L     Y+FR+ A N  G S P      +
Sbjct: 5990 VTGYVVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKP-V 6048

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
                   PP  P    + + +  + +L+W  P   GG PIT YIIE K  +G  W ++  
Sbjct: 6049 EAKNPFDPPEAPDRPDIVDYSPSTCSLEWKPPTDTGGRPITGYIIE-KRERGGDWIRVNH 6107

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR 1976
                  ++ ++ + E +   FRI A N  G   P++ S S+  +    +P PP AP   R
Sbjct: 6108 YPTPNTQYTVQGLSEGNRYEFRIIALNEAGPGKPSKPSNSIVAKVPKYLPGPPDAPRPDR 6167

Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
             +G N V  SW  P  DGGA + GY +  R   +  W     +      + +  L+E   
Sbjct: 6168 -IGRNCVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNYTVLGLTELEE 6226

Query: 2037 YMIRIYARNEIGLSEPLESDEPFKV 2061
            Y  R+ A NE+G S P       K+
Sbjct: 6227 YYFRVIAVNEVGPSAPSRPSALIKI 6251



 Score =  127 bits (306), Expect = 4e-27
 Identities = 127/529 (24%), Positives = 202/529 (38%), Gaps = 35/529 (6%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436
            D P  PG P  LE    SI I W +P + G S I  YVVE + +    W    +  +  T
Sbjct: 6451 DPPGAPGAPRGLESTEDSITIQWSKPRHDGGSHIQGYVVEKRIVGDNTWTKASHAMVKDT 6510

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               + NL  +  Y FR  A+N       S+ +E  K I   +    T +  ++++T    
Sbjct: 6511 TYRVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCI-SFRAPKITSDLSIRDMTVIAG 6569

Query: 1497 EDIELTCIFGGVPQPKVTWY------RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550
            E+  +T  F   PQPKV W+          +++    +  N                Y  
Sbjct: 6570 EEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYTI 6629

Query: 1551 IAFNDHGEVETSCVVGIQQKP--------VITISNEDIKQKHKV----GDEWLVTAVIEG 1598
               N  G    SC V +  +P        V  I+ +      +     G   +    +E 
Sbjct: 6630 KLTNSEGADSGSCKVNVVDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVER 6689

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            + P   +W K  +       Y++   E       +   R+ +     +   T    + + 
Sbjct: 6690 LEPVTGMWVK-VSAFVRSCHYDVMGLEPNRSYMFR--VRAENQYGLSDPLETLDPITAKF 6746

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
               V D P +P   ++  +I+  SV + W  P  DGG ++  Y +E  +  +  W    D
Sbjct: 6747 PFTVPDPPGRPN--ILDHDIN--SVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAAND 6802

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXX 1777
                  TY +  L  N EY FRV A+N  GFS+ +  S+ I +K    VPS         
Sbjct: 6803 FLVKETTYTVHSLLINHEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPS-PPGTPVVT 6861

Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTY 1835
             I    V + W   E +GGS I  Y +E ++ G  W           +  +  L+  +  
Sbjct: 6862 KIGKNYVDLKWSVPESDGGSRITGYMIEKRELGSIWMKCNDYNIVDTQYTVLNLTEGSEV 6921

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
            +FR+YA N  G S P  S   + I +   P  +P  F V    + +V L
Sbjct: 6922 EFRVYAINAAGKSDPSQSAQPVKI-REAAPGEKP--FFVKNLQNTAVAL 6967



 Score =  120 bits (289), Expect = 4e-25
 Identities = 147/634 (23%), Positives = 257/634 (40%), Gaps = 62/634 (9%)

Query: 469  VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
            V A+  + E+N T  +    +     L   E P+ +E  + P F E+   K + DG++V 
Sbjct: 195  VTAKNELGESNAT--ISLNFDSSFMMLTADEVPSPKE-GVRPTFTERPSIKQSEDGTSVI 251

Query: 529  FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN----VATLVIREVFPEDAGTFTCV 584
            F C+    P+P I W  +   ++     +M  + D     +  L + +V   D G +  V
Sbjct: 252  FSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVTNADEGEYRAV 311

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            A N  G   +T  L  E   +    +                 I +G  P F KKP+ + 
Sbjct: 312  ASNKLGEGVATINLHFEGKTASDKPK-----------------IPDGKAPRFPKKPEIR- 353

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIE-SDMHMYCSVLKITNVKK 702
              EG  +++EC L A PEP++ W FKG EI+ ++  IS+  +      +   + I   + 
Sbjct: 354  -QEGDKLVMECILEANPEPEVTW-FKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEA 411

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEP----PQVIEPLKSMIVRQGESVILSAQV 758
               G +   A N  G+++  I L  + G+  P    P  ++    +    G  + +  + 
Sbjct: 412  SDGGQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRC 471

Query: 759  VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSI----TILKPKKVKDEGVYTLKAENSE 811
               P+PT+ W K+ K ++A   L  K    T  +     I+K     D G Y   A N  
Sbjct: 472  KAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQF 531

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK-GTIKLVARVTRNPVPSITWYRNN 870
            G A  +  + +E   E   + P+F+ +   I  +EK G + + A V  +P P+  W ++ 
Sbjct: 532  GEATANVNLNIESDPEPTGQAPVFVEK-PTIKFEEKAGRVLMEALVRADPKPTSRWTKDG 590

Query: 871  ---EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
               ++   + T+T+  D      +        D G YKC   N  G+ +  A + +++E 
Sbjct: 591  KELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELN--ANLNLNIEV 648

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREII---QEGR-- 980
               +K   +       K V++EC    T   +  W+ +  ++  +D R  +   +EG   
Sbjct: 649  APTIKRPPRIVSVFNRK-VVIECVVISTSKPACSWFKDSSKVR-LDTRHCVNINEEGEGK 706

Query: 981  -XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
                         D G  K + K+++  T    +         L++ E K+K+    E  
Sbjct: 707  YVVQMEMLKAEKMDCGSYKVVAKNEKGETTFAGRGA--HHRDMLEEKEEKKKEEVKEEKM 764

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
               E A V  E   E    KK+K    KR  I+K
Sbjct: 765  EQQEAAQVEEESKKEEKAVKKDK---PKRREIKK 795



 Score =  109 bits (263), Expect = 6e-22
 Identities = 73/292 (25%), Positives = 127/292 (43%), Gaps = 13/292 (4%)

Query: 1206 ILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            ++   +  A LT +I  +   +++W+K    + ++ K+ +  D    TL +     +D+ 
Sbjct: 7353 VMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGEDED 7412

Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPND 1319
            EY C   ++      K ++ ++  PKI +    +R      +G +  + + +   P+P  
Sbjct: 7413 EYMCRAQNSGGIRSTKADISIKLAPKI-NVPPRFRDTAFFDKGENAVIKIPFIGNPRPRI 7471

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             W    + I+   H       + A L ++ V N D G Y+L  EN  G   V + + I D
Sbjct: 7472 TWQREGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELGSDSVIIKIQISD 7531

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
            +P PP  P +  I  +   + W  P   G + I  Y++E +E+    WI   N   T   
Sbjct: 7532 RPDPPRLPKVESILGTECVLTWQIPLWDGGANINNYIIEKRELPMESWIRCSNTRLTTAQ 7591

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            I+ L     Y+FR YA N    SD S  T     + ET   +P  +KP K +
Sbjct: 7592 IKGLSPGHKYQFRVYAENVYGRSDPSAVTS----VVET--PAPLTKKPKKKV 7637



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 8/218 (3%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            Q+ +  +N+ G+    T +  + I      P+ P +  V++ +     L W  P  +GG 
Sbjct: 7116 QYTLTVKNDSGS---VTGNFIVYITGVPGAPTAPLD--VTDISRHMCNLAWRPPVYDGGL 7170

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954
            P+T+Y++E K +   +W  I +         ++ + E  E +FR+ A N  G+  P T  
Sbjct: 7171 PVTHYVVERKDITYANWITINSFCKDC-SFTVQGLTEGQEYLFRVMAVNENGMGPPLTGV 7229

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
              ++ +     PSPP  P  +  VG + V   W  P  DGG+ + GY +  R++   +W 
Sbjct: 7230 NPIKAKAPYDPPSPPGTP-NVTEVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWT 7288

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             V +      + N+ +L E+  Y  R++A N+ G+SEP
Sbjct: 7289 MVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGMSEP 7326



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 118/519 (22%), Positives = 198/519 (38%), Gaps = 33/519 (6%)

Query: 1548 YKCIAFNDHGEVETSCVV---GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
            Y     ND G V  + +V   G+   P   +   DI  +H     W       G+P    
Sbjct: 7117 YTLTVKNDSGSVTGNFIVYITGVPGAPTAPLDVTDIS-RHMCNLAWRPPVYDGGLPVTHY 7175

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVT 1659
            +  +      N    N   K+ +    ++ L       + + A N  G     T    + 
Sbjct: 7176 VVERKDITYANWITINSFCKDCS--FTVQGLTEGQEYLFRVMAVNENGMGPPLTGVNPIK 7233

Query: 1660 LKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             K  YD PS P  P +  E+  + V +EW  P  DGG  +  Y +EK E  +N W  V  
Sbjct: 7234 AKAPYDPPSPPGTPNVT-EVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWTMVNQ 7292

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK--TALDVPSXXXXXXX 1775
                     +  L E+ +Y FRV A+N  G SE    S  + IK   A   P        
Sbjct: 7293 YICLPTQINVSNLIEDRQYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRN 7352

Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINT 1833
               + + S  +T   + K    P I +   +++     K+            +  +    
Sbjct: 7353 VMALQHRSATLTCQIAGKP--RPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGED 7410

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
              ++   A+N  G      +D  I +   +  P + R+    +    +V      P    
Sbjct: 7411 EDEYMCRAQNSGGIRST-KADISIKLAPKINVPPRFRDTAFFDKGENAVI---KIPFIGN 7466

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
              P   +  E +T++      + T       H + ++   D   +R++AEN +G    ++
Sbjct: 7467 PRPRITWQREGETIESGGHYSVETQQRHAILH-LRDVTNLDTGNYRLTAENELG----SD 7521

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
            S  ++++  +  P PP  P    ++G+  V+T W  P WDGGA +  Y I  R++    W
Sbjct: 7522 SVIIKIQI-SDRPDPPRLPKVESILGTECVLT-WQIPLWDGGANINNYIIEKRELPMESW 7579

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            +      + T +  I+ LS  H Y  R+YA N  G S+P
Sbjct: 7580 IRCSNTRLTTAQ--IKGLSPGHKYQFRVYAENVYGRSDP 7616



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 78/317 (24%), Positives = 152/317 (47%), Gaps = 33/317 (10%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM- 688
           +   P+F++KPK +  D+G+ ++ +C+L A P+P I W  +   +     + + ++    
Sbjct: 3   DNFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGKG 62

Query: 689 -HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQV--IEP--L 741
            +++   L + +V++   G Y V A N+ GE S  I L     E+  +  Q+  + P   
Sbjct: 63  GNIHDVQLILDDVEEEDAGLYKVKAKNKYGEVSASINLNFSPNEQPVDIKQIDGLAPTFA 122

Query: 742 KSMIVRQ---GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITI-L 792
           +  +++Q   G+ +    +++ +PRPTITW ++   V+      + T+ D  ++ +T+  
Sbjct: 123 QKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCKVTTEKDEKSYFVTMAF 182

Query: 793 KPKKVKDEGVYTLKAENSEGIAETS---------AVITVEE-PTEENAEPPLFINRFQEI 842
               V+D G Y + A+N  G +  +          ++T +E P+ +    P F  R   I
Sbjct: 183 TNVTVEDAGKYKVTAKNELGESNATISLNFDSSFMMLTADEVPSPKEGVRPTFTER-PSI 241

Query: 843 TVKEKGT-IKLVARVTRNPVPSITW-YRNNEIISPS-ETITQNFDGENIELVITNVD--S 897
              E GT +    R   NP P+I W ++  ++   +   +    DG+   +VI  V+  +
Sbjct: 242 KQSEDGTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVT 301

Query: 898 EIDSGDYKCVASNSAGK 914
             D G+Y+ VASN  G+
Sbjct: 302 NADEGEYRAVASNKLGE 318



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 144/662 (21%), Positives = 249/662 (37%), Gaps = 68/662 (10%)

Query: 466  KGWVPAQYLMDENNYTQYLQ-KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG 524
            K W  A++L+      +Y   +KL+  +DK  + +      Q  AP FV + +   T +G
Sbjct: 7967 KEW--AKFLLPIGRLAEYSSLRKLH--LDKYRIHDTHFDRRQC-APRFVIRPQNAFTYEG 8021

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
             +V+F C++     P + WF     ++ S  +   Y  ++ +  VI  V  ED G +   
Sbjct: 8022 QSVKFSCRIVAVAAPTVCWFHNNMELRQSVKYMKRYSGEDYS-FVINRVKLEDRGEYIIR 8080

Query: 585  AKNAAGFASSTTELIVEAPLSDHGS----EMTVXXXXXXXXXXXXADILEGIPP-TFSKK 639
            A+N  G       L V+ PL         +  +             +  EG P  TF  +
Sbjct: 8081 AENHYGAREEPVFLNVQ-PLPPEAPPYRPQEQIIRRRQPLTYKLWQEEGEGAPSFTFLLR 8139

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+     +   +L  C L   P P + W +KG + +   + S +    +      ++I N
Sbjct: 8140 PRVIQCHQTCKLL--CCLAGKPVPTVKW-YKGSQELSKFDYSQSHADGV----VTIEIVN 8192

Query: 700  VKKFQEGTYTVVAVNREG--EASLPIVLK----IKTGEKEPPQVIEPLKSMIVRQGESVI 753
             K    G Y  VA N  G  E S  ++++    I+T  K+ P    P   +      S  
Sbjct: 8193 CKPADSGKYRCVATNSLGTDETSCVVIVEDRRYIETTIKDLPPPPTPAIRVDDTSSSSYF 8252

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             S    G         +++   K     S   + +      + +K  G    K ++S G 
Sbjct: 8253 TSTHKDG---------RSSTSTKVEAASSSSTSSAAASGAKRTLKPYG----KRQDSTGS 8299

Query: 814  AETSAVITVE---EPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRN 869
               S   T E    P +    PP F     + + +K+   + L   V  +P P ++W+++
Sbjct: 8300 TSRSRSATKELELPPDDSLMGPPGFSGELPKTLAIKDGEALCLKCTVKGDPEPQVSWFKD 8359

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV---- 925
             E +S S+ I   +      L I  V  E D G Y C A++S G +    +++I      
Sbjct: 8360 GEPLSSSDIIDLKYRQGLASLTINEVFPE-DEGLYVCKATSSLGSAETKCKLSISPMEQQ 8418

Query: 926  --------EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREI 975
                    +K+  +     S E  +G    L C+          W HN+KEI        
Sbjct: 8419 INGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHNEKEIKPSKDFLY 8478

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKC-----IVKDQETSTMLVV----KETIPEFIRKLQDF 1026
            + EG             D G   C     + +   T T+ V+    ++  P F +  +  
Sbjct: 8479 VTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEKKQPAFKKFPRSQ 8538

Query: 1027 EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY-IRNTSVHDEG 1085
             V E   A   V+   +   V W +DG+ +     ++ F++ G     Y I +    D G
Sbjct: 8539 TVMEGKSATFSVKFEKDPLKVSWIKDGKPVDESSPRFKFQQEGKKEFSYEIPSCLPTDVG 8598

Query: 1086 EY 1087
            +Y
Sbjct: 8599 QY 8600



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 71/250 (28%), Positives = 103/250 (41%), Gaps = 6/250 (2%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            K  K   A FE E +K D+  +WF    E+      +   +G    L I    LDD G+Y
Sbjct: 1314 KEGKDKFAKFEAEFSKKDSKPKWFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKY 1373

Query: 1177 SCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234
            + E     C+ ILTV+E  P   F   LP+ I      DA L  ++      V W+K + 
Sbjct: 1374 TVECMGIACSCILTVQEPDPDFKFVRPLPKKISSYTTKDATLEAQVNSHKAIVHWFKGEE 1433

Query: 1235 VIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVD 1292
             IE+ EKF    D+     L I+  ++ D+ +YT  +    K  T+  + +V+ P K   
Sbjct: 1434 KIEEDEKFETYKDMTGTVRLTIKNASKKDKGKYTAKIFRCEKEFTETLLSIVDQPFKFTK 1493

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
              +   +   S V L  D     +   EW     K+    K  K   D K   L  K + 
Sbjct: 1494 QLKSKTVTENSKVILECDVDE-AEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSIS 1552

Query: 1352 NTDAGIYKLR 1361
              DAG Y  R
Sbjct: 1553 MDDAGNYSCR 1562



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 63/230 (27%), Positives = 111/230 (48%), Gaps = 15/230 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKT-GEKEPPQVIEPLKSMIVRQGE 750
            + ++N+ + ++  + V A N  G    ++    ++IK      PP++I PL++++  Q  
Sbjct: 7300 INVSNLIEDRQYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRNVMALQHR 7359

Query: 751  SVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            S  L+ Q+ G PRP I+W K  + +          DGDT+++T+      +DE  Y  +A
Sbjct: 7360 SATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTV-HDVYGEDEDEYMCRA 7418

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSITW 866
            +NS GI  T A I+++   + N  P     RF++    +KG   ++      NP P ITW
Sbjct: 7419 QNSGGIRSTKADISIKLAPKINVPP-----RFRDTAFFDKGENAVIKIPFIGNPRPRITW 7473

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             R  E I      +      +  L + +V + +D+G+Y+  A N  G  S
Sbjct: 7474 QREGETIESGGHYSVETQQRHAILHLRDV-TNLDTGNYRLTAENELGSDS 7522



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 45/173 (26%), Positives = 80/173 (46%), Gaps = 1/173 (0%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++ +++ G  + + +     PQP  EW    K ++  K T     S    L + K    D
Sbjct: 5872 KKLKVRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARRED 5931

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTII 1413
            +G + +  EN  G    ++ V ++DKP PP G     E+ + ++++ W  P++ G + + 
Sbjct: 5932 SGTFTITAENPYGKDSADIEVIVVDKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAEVT 5991

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             YVVE     TT   S +   K   +++ L+    YRFR  A N   +S+  E
Sbjct: 5992 GYVVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLE 6044



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 95/391 (24%), Positives = 157/391 (40%), Gaps = 24/391 (6%)

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTS 1654
            EG P P   W +NG ++       IT++E     +  I ++       Y   A+N AG +
Sbjct: 6978 EGKPTPTARWLRNGREVTLGGR--ITSEESKGKFKLFISDMWEVDEGDYACVAANDAGQA 7035

Query: 1655 SVEVTLKVYDKP--SKPEGPVIMREISRESVTIEWKP--PLDDGGLELTKYAIEKHEPDN 1710
            +    +K+ + P  ++ +  + + E     + I +    PLD   + L++  +   E   
Sbjct: 7036 TSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFTGDLPLD---VTLSQNGLPVEESQR 7092

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
               +K    D  +  +  + + ++    + +  +N  G   ++    IV  T   VP   
Sbjct: 7093 ---LKFTVFDEFIIIFIREVVKQDAG-QYTLTVKNDSG---SVTGNFIVYITG--VPGAP 7143

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQK 1828
                    I      + W P   +GG P+  Y VE K      W          +  +Q 
Sbjct: 7144 TAPLDVTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWITINSFCKDCSFTVQG 7203

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
            L+    Y FR+ A NE G   P T  + I       PPS P    V+E     V L+W +
Sbjct: 7204 LTEGQEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPSPPGTPNVTEVGGDFVHLEWDK 7263

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            P  +GGS I  Y +E + +    WT +        +  + N+ E  +  FR+ AEN  G+
Sbjct: 7264 PAHDGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGM 7323

Query: 1949 SLP-TESQSVRLEKHATVPSPPTAPLEIRMV 1978
            S P T S SVR+ K     +PP     +R V
Sbjct: 7324 SEPSTCSTSVRI-KDPNAATPPEIITPLRNV 7353



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 109/425 (25%), Positives = 165/425 (38%), Gaps = 47/425 (11%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKK-CKHT-KPSIDSK---SASLTIKKVENTDAG 1356
            G+ V       A PQP   W    K +++  +H  K   D K      L + KV N D G
Sbjct: 247  GTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVTNADEG 306

Query: 1357 IYKLRLENNCGHADVEMNV-----TILDKP------SP--PGKPNILEIDSSSINICW-- 1401
             Y+    N  G     +N+     T  DKP      +P  P KP I +     +  C   
Sbjct: 307  EYRAVASNKLGEGVATINLHFEGKTASDKPKIPDGKAPRFPKKPEIRQEGDKLVMECILE 366

Query: 1402 --DEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
               EPE T    T I  + E   I   + I  K+      +I   + +   ++R  A N 
Sbjct: 367  ANPEPEVTWFKGTEI--IQEQGRISMYKKICGKDQFIVSVTIMKPEASDGGQWRCNAFNP 424

Query: 1459 VDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
               S+A+    + K     +  +PT ++KP   I  E    I +       PQP V W++
Sbjct: 425  FGDSNANIALNFEKGKAIPEGFAPTFLDKP-SIIPNESGTMITMKVRCKAKPQPTVEWFK 483

Query: 1518 DGKKLKTAK--------ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            DGKKL+ AK         T E                  YKC+A N  GE   +  + I+
Sbjct: 484  DGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFGEATANVNLNIE 543

Query: 1569 QKPVIT------ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
              P  T      +    IK + K G   L+ A++   P P   W K+G +L+  +     
Sbjct: 544  SDPEPTGQAPVFVEKPTIKFEEKAG-RVLMEALVRADPKPTSRWTKDGKELDVARVTATV 602

Query: 1623 TKEKTSVIRIK-ELKR---SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
            TKEK  + RI+ EL++   +    Y     N  G  +  + L +   P+    P I+   
Sbjct: 603  TKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTIKRPPRIVSVF 662

Query: 1679 SRESV 1683
            +R+ V
Sbjct: 663  NRKVV 667



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 47/156 (30%), Positives = 78/156 (50%), Gaps = 8/156 (5%)

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPN 1388
            K S   +S    +  +E   + ++++R EN  G +D +E    I  K     P PPG+PN
Sbjct: 6699 KVSAFVRSCHYDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFPFTVPDPPGRPN 6758

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTN 1446
            IL+ D +S+ + WD P + G S I  Y VEY+++  T W +  +  + +T  ++ +L  N
Sbjct: 6759 ILDHDINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVKETTYTVHSLLIN 6818

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
              Y FR  A N    S  S  ++  K+  +  + SP
Sbjct: 6819 HEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPSP 6854



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 50/176 (28%), Positives = 86/176 (48%), Gaps = 7/176 (3%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLT 1346
            PKI+    + RIK G  + + VDY   PQP+  W  + K ++   + T  +I++ S   T
Sbjct: 5564 PKILGPLYDVRIKAGQVLHVDVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHT 5623

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPE 1405
            +  + N D+G Y++R++N  G  +    V +LD P  P  P +  E+ ++S+ + W  P 
Sbjct: 5624 VNTMRN-DSGEYRIRVKNESGQDEATFQVIVLDTPGAPEGPLVYEEVQANSVVMSWKPPV 5682

Query: 1406 NTGNSTIIYYVVEYQEID-TTEWISVKNIT---KTQTSIQNLKTNSSYRFRAYAVN 1457
            + G S I  YV+E ++I     W+   N     +   ++  L   + Y  R  A N
Sbjct: 5683 DDGGSPITGYVIEKRDISHGGGWVPAVNWVDPKQNHATVPRLLEGTQYDSRVRAEN 5738



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 58/216 (26%), Positives = 94/216 (43%), Gaps = 21/216 (9%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-----------WTK 1914
            PS P N  VSE  S S  + +  P+ +GG P+T YIIE +    K+           W +
Sbjct: 1764 PSPPTNVEVSEIFSTSCLITFGPPKDDGGLPLTYYIIERQDFSVKASHPRIWERTGGWAQ 1823

Query: 1915 IVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973
            +  +          E+++ K +  F+++  N +G S P     V L K           +
Sbjct: 1824 VAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLGPSDPFIHPKVILAKDPWDEPGKILHV 1883

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR--------DVTK-TMWMEVGKVDVNTL 2024
            E+   G +     W  PE DGGAP+ GY I  R        +V + + W +  ++  +  
Sbjct: 1884 EVNDWGPDHADLRWSRPETDGGAPITGYVIEFRTRAMPGAGEVDRFSDWAKGIEIQGDVT 1943

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
            +  I DL E + Y  R+ A N+ G  EP +  +P +
Sbjct: 1944 EGTIPDLKEGNQYEFRVRAVNKAGPGEPSDPTKPIQ 1979



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 58/250 (23%), Positives = 107/250 (42%), Gaps = 39/250 (15%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P  +  LR        +    CQ+ G PRP I+WF+    +  S  + M  D D   TL 
Sbjct: 7344 PEIITPLRNVMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTY-TLT 7402

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXXXXXADI 628
            + +V+ ED   + C A+N+ G  S+  ++ ++ AP  +                      
Sbjct: 7403 VHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKIN---------------------- 7440

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
               +PP F       + D+G + +++   +  P P I W  +GE I    + SV  +   
Sbjct: 7441 ---VPPRFR---DTAFFDKGENAVIKIPFIGNPRPRITWQREGETIESGGHYSVETQ-QR 7493

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            H   ++L + +V     G Y + A N  G  S  +++KI+  ++  P  +  ++S++   
Sbjct: 7494 H---AILHLRDVTNLDTGNYRLTAENELGSDS--VIIKIQISDRPDPPRLPKVESIL--- 7545

Query: 749  GESVILSAQV 758
            G   +L+ Q+
Sbjct: 7546 GTECVLTWQI 7555



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 23/215 (10%)

Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-------ALPTKS 782
           G+   P   +  K      G  +I   ++  +P+P+I W + + PVK        +    
Sbjct: 2   GDNFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGK 61

Query: 783 DGDTHSI-TILKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAEPPLFI 836
            G+ H +  IL   + +D G+Y +KA+N  G  E SA I +     E+P +      L  
Sbjct: 62  GGNIHDVQLILDDVEEEDAGLYKVKAKNKYG--EVSASINLNFSPNEQPVDIKQIDGLAP 119

Query: 837 NRFQEITVK-EKG--TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGEN--IE 889
              Q+  +K E+G   IK   R+  +P P+ITW+R+   +  S    +T   D ++  + 
Sbjct: 120 TFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCKVTTEKDEKSYFVT 179

Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           +  TNV  E D+G YK  A N  G+S+    +  D
Sbjct: 180 MAFTNVTVE-DAGKYKVTAKNELGESNATISLNFD 213



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 92/440 (20%), Positives = 163/440 (37%), Gaps = 42/440 (9%)

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            T KL  E  E  P      R   I+      LL      P P  +W   S+ + K  +++
Sbjct: 8120 TYKLWQEEGEGAPSFTFLLRPRVIQCHQTCKLLCCLAGKPVPTVKWYKGSQELSKFDYSQ 8179

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD--------KPSPPGKP 1387
               D    ++ I   +  D+G Y+    N+ G  +    V + D        K  PP   
Sbjct: 8180 SHADGV-VTIEIVNCKPADSGKYRCVATNSLGTDETSCVVIVEDRRYIETTIKDLPPPPT 8238

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS--VKNITKTQTSIQNLKT 1445
              + +D +S +  +      G S+    V       T+   +   K   K     Q+  T
Sbjct: 8239 PAIRVDDTSSSSYFTSTHKDGRSSTSTKVEAASSSSTSSAAASGAKRTLKPYGKRQD-ST 8297

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCI 1504
             S+ R R+ A  E+++              ++ +  P     L K +  +  E + L C 
Sbjct: 8298 GSTSRSRS-ATKELELPP-----------DDSLMGPPGFSGELPKTLAIKDGEALCLKCT 8345

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P+P+V+W++DG+ L ++        +                 Y C A +  G  E
Sbjct: 8346 VKGDPEPQVSWFKDGEPLSSSDIIDLKYRQGLASLTINEVFPEDEGLYVCKATSSLGSAE 8405

Query: 1561 TSCVVGI----QQ--------KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            T C + I    QQ          +  I+   + Q+   G    ++  I G    +V+W  
Sbjct: 8406 TKCKLSISPMEQQINGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLH 8465

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            N  +++  K++   T+  T +++I E+    +  YT EA N  G +    TL V     +
Sbjct: 8466 NEKEIKPSKDFLYVTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEE 8525

Query: 1669 PEGPVIMREISRESVTIEWK 1688
             + P   ++  R    +E K
Sbjct: 8526 KKQPA-FKKFPRSQTVMEGK 8544



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 65/326 (19%), Positives = 131/326 (40%), Gaps = 35/326 (10%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDV--KKRTLI---IRKCTEDDQCEYTCVLL----DAKST 1276
            +VTW+K   +I++  + ++   +  K + ++   I K    D  ++ C       D+ + 
Sbjct: 372  EVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEASDGGQWRCNAFNPFGDSNAN 431

Query: 1277 TKLKVE----VVE-FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
              L  E    + E F P  +D       + G+ +T+ V  +A PQP  EW  + K ++  
Sbjct: 432  IALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRCKAKPQPTVEWFKDGKKLEAA 491

Query: 1332 KHT-----KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
            K       K + +    S  +K     DAG YK    N  G A   +N+ I   P P G+
Sbjct: 492  KRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFGEATANVNLNIESDPEPTGQ 551

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW------ISVKNITKTQTSI 1440
              +  ++  +I       E      ++  +V      T+ W      + V  +T T T  
Sbjct: 552  APVF-VEKPTIKF-----EEKAGRVLMEALVRADPKPTSRWTKDGKELDVARVTATVTKE 605

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNE 1497
            ++         R     +  +   +   E+ ++     +    +PT+++P + I +  N 
Sbjct: 606  KDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTIKRPPR-IVSVFNR 664

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK 1523
             + + C+     +P  +W++D  K++
Sbjct: 665  KVVIECVVISTSKPACSWFKDSSKVR 690



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            VY + A      ++++  + + E      E P F+   Q   V    ++ L       P 
Sbjct: 6925 VYAINAAGKSDPSQSAQPVKIREAAP--GEKPFFVKNLQNTAVALHKSVTLECEAEGKPT 6982

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            P+  W RN   ++    IT        +L I+++  E+D GDY CVA+N AG+++  A V
Sbjct: 6983 PTARWLRNGREVTLGGRITSEESKGKFKLFISDM-WEVDEGDYACVAANDAGQATSIAHV 7041

Query: 922  TI 923
             I
Sbjct: 7042 KI 7043



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 69/310 (22%), Positives = 130/310 (41%), Gaps = 21/310 (6%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PPEIIT L+N    +   AT   ++  K    + WFK   E+  S    +  DG    L 
Sbjct: 7343 PPEIITPLRNVMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLT 7402

Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVE 1219
            ++D   +D  EY C   NS       A ++++  P IN   R  +        +A + + 
Sbjct: 7403 VHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKINVPPRFRDTAFFDKGENAVIKIP 7462

Query: 1220 -IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
             I +    +TW ++   IE    +++ +  +   L +R  T  D   Y     +     +
Sbjct: 7463 FIGNPRPRITWQREGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELGSDS 7522

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
              +K+++ + P    D  R  +++       ++ +Q  P  +    +N+ II+K +    
Sbjct: 7523 VIIKIQISDRP----DPPRLPKVESILGTECVLTWQ-IPLWDGGANINNYIIEKRELPME 7577

Query: 1337 S-IDSKSASLTIKKVENTDAG-IYKLRL--ENNCGHADVEMNVTILDKPSP---PGKPNI 1389
            S I   +  LT  +++    G  Y+ R+  EN  G +D     ++++ P+P     K  +
Sbjct: 7578 SWIRCSNTRLTTAQIKGLSPGHKYQFRVYAENVYGRSDPSAVTSVVETPAPLTKKPKKKV 7637

Query: 1390 LEIDSSSINI 1399
             E+D +   I
Sbjct: 7638 YEVDETGKKI 7647



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 15/185 (8%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L C++   P P+I+W FKG   + + +   A+  D   Y   L + +V    E  Y   A
Sbjct: 7363 LTCQIAGKPRPNISW-FKGMRELCN-SAKYAMNRDGDTY--TLTVHDVYGEDEDEYMCRA 7418

Query: 713  VNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
             N  G  S    + IK   K   PP+  +   +    +GE+ ++    +GNPRP ITW +
Sbjct: 7419 QNSGGIRSTKADISIKLAPKINVPPRFRD---TAFFDKGENAVIKIPFIGNPRPRITWQR 7475

Query: 771  NNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
              + +++    S      H+I  L+     D G Y L AEN  G    S +I ++    +
Sbjct: 7476 EGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELG--SDSVIIKIQ--ISD 7531

Query: 829  NAEPP 833
              +PP
Sbjct: 7532 RPDPP 7536



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 13/183 (7%)

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            + +P   + L   EV +     L  +I   T  DVVW  + + IKP K+ + +   G   
Sbjct: 8427 DKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHNEKEIKPSKD-FLYVTEGDTY 8485

Query: 1073 KLYIRNTSVHDEGEYSCILRDE------SCTAEVTVV---ELPPEIITRLQNQKVNKGNK 1123
             L I      D G Y+C   ++      +CT  V +    +  P      ++Q V +G  
Sbjct: 8486 LLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEKKQPAFKKFPRSQTVMEGKS 8545

Query: 1124 ATFEIELTKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVG 1181
            ATF ++  K    V W KDG  + + S   +   +GKK+   +I  C   D G+Y  +  
Sbjct: 8546 ATFSVKFEKDPLKVSWIKDGKPVDESSPRFKFQQEGKKEFSYEIPSCLPTDVGQYVVKAT 8605

Query: 1182 NSK 1184
            + K
Sbjct: 8606 SKK 8608



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 67/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%)

Query: 1120 KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL--TIDGKKQ---KLKIYDCDLDDA 1173
            +G+K   E  L    +  V WFK    IQ    I +   I GK Q    + I   +  D 
Sbjct: 355  EGDKLVMECILEANPEPEVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEASDG 414

Query: 1174 GEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFI----LVPANTDAYLTVEI----- 1220
            G++ C      G+S     L  E+         P F+    ++P  +   +T+++     
Sbjct: 415  GQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRCKAK 474

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC-----EYTCVLL---- 1271
            P  T++  W+K    +E  ++  +        +    C   D C     +Y CV +    
Sbjct: 475  PQPTVE--WFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFG 532

Query: 1272 DAKSTTKLKVEVVEFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            +A +   L +E    P    P  V+       ++   V +    +A P+P   W  + K 
Sbjct: 533  EATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGRVLMEALVRADPKPTSRWTKDGKE 592

Query: 1328 IKKCKHT----KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            +   + T    K   D     + ++K + TD G+YK  ++N  G  +  +N+ I   P+ 
Sbjct: 593  LDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTI 652

Query: 1384 PGKPNILEIDSSSINI 1399
               P I+ + +  + I
Sbjct: 653  KRPPRIVSVFNRKVVI 668



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 10/194 (5%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G  P F K  +   V     + LEC     P P   WL  G E+     +   I S+   
Sbjct: 6951 GEKPFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREV----TLGGRITSEESK 7006

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L I+++ +  EG Y  VA N  G+A+   +  +K G   PP++ +   ++ + +G+
Sbjct: 7007 GKFKLFISDMWEVDEGDYACVAANDAGQAT--SIAHVKIG--NPPRITQMQDALYLPEGD 7062

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAE 808
            +  +     G+    +T  +N  PV+       +  D   I  ++    +D G YTL  +
Sbjct: 7063 NTKIKIYFTGDLPLDVTLSQNGLPVEESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVK 7122

Query: 809  NSEGIAETSAVITV 822
            N  G    + ++ +
Sbjct: 7123 NDSGSVTGNFIVYI 7136



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 11/135 (8%)

Query: 696  KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749
            ++ ++ + +   + V AVN  G     EASLPI  K +   K  P++    L+ + VR+G
Sbjct: 4046 RVNDLDEGETYEFRVRAVNEAGPSDPSEASLPITCKPR---KLAPKIDRRNLRDLTVREG 4102

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV-KDEGVYTLKA 807
            E ++L  +V+G P P + W    KP+K     + +   ++   +  + + K  GV  + A
Sbjct: 4103 EPILLDVKVIGEPPPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVA 4162

Query: 808  ENSEGIAETSAVITV 822
             N  G  E    ITV
Sbjct: 4163 TNQHGRDEAEITITV 4177



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 5/134 (3%)

Query: 697  ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            + N+ + QE  + ++AVN+ G  E S P    I       P+++ PL  + ++ G+ + +
Sbjct: 5524 VPNLTEGQEYEFRIIAVNKAGNSEPSEPSDAVICRPRHLAPKILGPLYDVRIKAGQVLHV 5583

Query: 755  SAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
                +G P+P + W  ++K   +    T +  + HS+         D G Y ++ +N  G
Sbjct: 5584 DVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHTVNTMRNDSGEYRIRVKNESG 5643

Query: 813  IAE-TSAVITVEEP 825
              E T  VI ++ P
Sbjct: 5644 QDEATFQVIVLDTP 5657



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 62/270 (22%), Positives = 104/270 (38%), Gaps = 20/270 (7%)

Query: 1719 VDRDVETYCIQKLN----ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            ++RD +TY +   +    +  EYM R  AQN  G         I +   ++VP       
Sbjct: 7392 MNRDGDTYTLTVHDVYGEDEDEYMCR--AQNSGGIRSTKADISIKLAPKINVPPRFRDTA 7449

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXARIQKLSIN 1832
                 +N  + I +  + +    P I ++ E +  + G  +            ++ ++  
Sbjct: 7450 FFDKGENAVIKIPFIGNPR----PRITWQREGETIESGGHYSVETQQRHAILHLRDVTNL 7505

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
             T  +R+ A NE+G+        KI I     PP  P+   V         L W  P  +
Sbjct: 7506 DTGNYRLTAENELGSDSVII---KIQISDRPDPPRLPK---VESILGTECVLTWQIPLWD 7559

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
            GG+ I NYIIE + +  +SW +      +  +  I+ +    +  FR+ AEN  G S P+
Sbjct: 7560 GGANINNYIIEKRELPMESWIRCSNTRLTTAQ--IKGLSPGHKYQFRVYAENVYGRSDPS 7617

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
               SV          P     E+   G  I
Sbjct: 7618 AVTSVVETPAPLTKKPKKKVYEVDETGKKI 7647



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 502  TSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            T + ++M P I    L P  +  G +  F+  V G P P+  W      IKPS    + Y
Sbjct: 4670 TVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRY 4729

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +D N   L +     E +GT+T VA+NA G  S+  E+IV
Sbjct: 4730 NDYN-TKLRVTGATREQSGTYTIVAENANGKDSADVEVIV 4768



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 19/152 (12%)

Query: 697  ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            IT +K+ ++  + V AVN+ G     +++LP   + K   ++P      +K ++++ G+ 
Sbjct: 3154 ITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTARAKF--RKPRIDRTNVKDVVIKVGQQ 3211

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA-----------LPTKSDGDTHSITILKPKKVKDE 800
             +    V+G+P+PT TW   +KP+ +           L   S G+   + I+K ++ K  
Sbjct: 3212 YLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKAQR-KMS 3270

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
            G Y L A N  G       IT+  P  +   P
Sbjct: 3271 GKYVLTATNEHGEDSVKIDITILGPPSKPKGP 3302



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T + E +VEG P P++TW  Q A IK  +       +D++ T+VIR+    D G +  
Sbjct: 3512 GITFKNESKVEGEPDPKVTWSLQGAPIKNER--VTITSEDHLTTIVIRKAKRSDTGVYKI 3569

Query: 584  VAKNAAGFASSTTELIV 600
             AKN +G   +  +LIV
Sbjct: 3570 FAKNDSGTDEAELDLIV 3586



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 56/263 (21%), Positives = 103/263 (39%), Gaps = 17/263 (6%)

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            ++PE D      G  I   E  S+ ++ +D ++  +   + N+ +  E  + V A+N  G
Sbjct: 6873 SVPESDGGSRITGYMIEKRELGSIWMKCNDYNIVDTQYTVLNLTEGSEVEFRVYAINAAG 6932

Query: 718  -----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
                 +++ P+ ++ +    E P  ++ L++  V   +SV L  +  G P PT  W +N 
Sbjct: 6933 KSDPSQSAQPVKIR-EAAPGEKPFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNG 6991

Query: 773  KPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            + V      T  +        +      DEG Y   A N  G A + A + +        
Sbjct: 6992 REVTLGGRITSEESKGKFKLFISDMWEVDEGDYACVAANDAGQATSIAHVKI-------G 7044

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
             PP        + + E    K+    T +    +T  +N   +  S+ +      E I +
Sbjct: 7045 NPPRITQMQDALYLPEGDNTKIKIYFTGDLPLDVTLSQNGLPVEESQRLKFTVFDEFIII 7104

Query: 891  VITNVDSEIDSGDYKCVASNSAG 913
             I  V  + D+G Y     N +G
Sbjct: 7105 FIREVVKQ-DAGQYTLTVKNDSG 7126



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 40/146 (27%), Positives = 72/146 (49%), Gaps = 13/146 (8%)

Query: 697  ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            + ++ + +E  + V+AVN+ G     ++S P+V K +   ++P    + L+ +I++    
Sbjct: 5230 VPDLTEGEEYQFRVIAVNKAGNSDPSDSSQPVVCKARF--EKPGIDTKDLEDLIIKVNTR 5287

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            +  +  + G PRP ++W  N  PV   + +  ++ G    + I   ++  D G YTL  E
Sbjct: 5288 LNYTVPIRGAPRPKVSWTVNGSPVVESERVDLQTYGKQTILDIPFAQRT-DSGRYTLTLE 5346

Query: 809  NSEGIAETSAVITVEEPTEENAEPPL 834
            N  G  + SA  TV   T   AE PL
Sbjct: 5347 NDLG--KVSASGTVTSLTSLTAEGPL 5370



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 3/129 (2%)

Query: 797  VKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
            +K+  VY+  +KA N  GI E S          +N +P +    F+ +T+K   + K   
Sbjct: 2259 LKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGRSHKWAV 2318

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
                 P P +TW R   ++S ++ I       + E+ IT+   + D+G Y     N  G+
Sbjct: 2319 DYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRK-DAGLYTLKIENRNGQ 2377

Query: 915  SSHGARVTI 923
             S    + +
Sbjct: 2378 DSETVELVV 2386



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 9/137 (6%)

Query: 700  VKKFQEGT---YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVI 753
            V   +EGT   + V A N+ G  EAS P    +   +   P++     KS+ ++ G S  
Sbjct: 2256 VPGLKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGRSHK 2315

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             +   VG P P +TW +    +         + D H+   +     KD G+YTLK EN  
Sbjct: 2316 WAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLKIENRN 2375

Query: 812  G-IAETSAVITVEEPTE 827
            G  +ET  ++ + +P++
Sbjct: 2376 GQDSETVELVVLGKPSK 2392



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 5/94 (5%)

Query: 641  KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
            K   +  G ++  +  +   P P + W+ K +E V D NI + +  D   Y +   + + 
Sbjct: 2612 KQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQE-VKDSNIEI-VNVD---YNTKFNMIDA 2666

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
            K+ Q GTY ++A NR+G+    + + + +G  +P
Sbjct: 2667 KRKQTGTYKIIATNRDGKDEAAVEIVVLSGPGKP 2700



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 9/138 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
            ++IT+V+   E  + VVA N+ G     +AS  ++ K +     P    + +    +R G
Sbjct: 3455 IRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRF--LAPRIDRKSVGRKTIRSG 3512

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAE 808
             +    ++V G P P +TW     P+K        + H  TI ++  K  D GVY + A+
Sbjct: 3513 ITFKNESKVEGEPDPKVTWSLQGAPIKNERVTITSEDHLTTIVIRKAKRSDTGVYKIFAK 3572

Query: 809  NSEGIAETSA-VITVEEP 825
            N  G  E    +I + +P
Sbjct: 3573 NDSGTDEAELDLIVIGKP 3590



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 5/132 (3%)

Query: 698  TNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVIL 754
            TN+ +  E  + + AVNR G  E S P    I      PP++    L+ + +  G  +  
Sbjct: 4343 TNLIEGMEYQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKY 4402

Query: 755  SAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
               + G P PT +W    + ++A    T ++ D +S  +++     D G Y + A NS G
Sbjct: 4403 DCDISGEPPPTASWTYEGRKLEASRHVTIANIDYNSKLVIRDTVRADSGEYVITATNSSG 4462

Query: 813  IAETSAVITVEE 824
              + +  +TV +
Sbjct: 4463 KDQVTVRVTVTD 4474



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 64/274 (23%), Positives = 103/274 (37%), Gaps = 29/274 (10%)

Query: 1132 KGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS------ 1183
            KGD    V WFKDG  +  S+ I L        L I +   +D G Y C+  +S      
Sbjct: 8347 KGDPEPQVSWFKDGEPLSSSDIIDLKYRQGLASLTINEVFPEDEGLYVCKATSSLGSAET 8406

Query: 1184 KCTAILTVEEPSINFTL-------RLPEFIL---VPANTDAYLTVEIPDET-LDVTWYKK 1232
            KC   ++  E  IN          R+ + +L   VP  T   L+ +I   T  DV W   
Sbjct: 8407 KCKLSISPMEQQINGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHN 8466

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEV---VE 1285
            +  I+ ++ F  +++     L I +   +D   YTC       +  ST  L V +    +
Sbjct: 8467 EKEIKPSKDFLYVTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEK 8526

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC--KHTKPSIDSKSA 1343
              P    + R   +  G   T  V ++  P     WI + K + +   +        K  
Sbjct: 8527 KQPAFKKFPRSQTVMEGKSATFSVKFEKDPL-KVSWIKDGKPVDESSPRFKFQQEGKKEF 8585

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            S  I     TD G Y ++  +  G      ++ +
Sbjct: 8586 SYEIPSCLPTDVGQYVVKATSKKGDTTAAFSLNV 8619



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 35/129 (27%), Positives = 54/129 (41%), Gaps = 3/129 (2%)

Query: 475  MDENNYTQYLQKKLNEKIDKLP--VFEKPTSEEQSMAPIFVE-KLRPKHTPDGSTVQFEC 531
            + E    Q+  K +N+     P    +  T++ + +AP+     L       G  ++F+C
Sbjct: 3754 LTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTNLENITVRAGQMIKFDC 3813

Query: 532  QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
             V G P P+ TWF   A     Q      ++D+   +VI        GTF   A N AG 
Sbjct: 3814 NVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGH 3873

Query: 592  ASSTTELIV 600
               T E+IV
Sbjct: 3874 DEVTIEVIV 3882



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 40/148 (27%), Positives = 63/148 (42%), Gaps = 8/148 (5%)

Query: 696  KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
            ++  +K+     + VVAVN+ G  + S P    +       P +  E LK +  R  + V
Sbjct: 2856 RVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLINREKLKKITTRASQKV 2915

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENS 810
             L   V G P P I W   NK V+  P         +T   L   + +  G+Y + A+N 
Sbjct: 2916 FLEVDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAERRHTGIYKIHAKND 2975

Query: 811  EGIAETS-AVITVEEPTEENAEPPLFIN 837
             G  E    +I ++ P +   E PL I+
Sbjct: 2976 SGSDEAELEIIVLDRPGK--PEGPLEIS 3001



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 48/187 (25%), Positives = 81/187 (43%), Gaps = 19/187 (10%)

Query: 699  NVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEPL--KSMIVRQGESVI 753
            +V + ++  Y VVA N+ G +  S P   +  K   + P   ++ L  K + VR GE + 
Sbjct: 5824 SVNEGEQYQYRVVANNKMGPSNPSDPSQAITAKPMREAPKLYLDGLLGKKLKVRAGEPID 5883

Query: 754  LSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            +   + G P+P   W K  K   P K    ++  D   + + K ++ +D G +T+ AEN 
Sbjct: 5884 IKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARR-EDSGTFTITAENP 5942

Query: 811  EGIAETS-AVITVEEPTEENAEPPLFINRFQEITV-------KEKGTIKLVARVTRNPVP 862
             G       VI V++P       PL        TV       ++ G  ++   V   P P
Sbjct: 5943 YGKDSADIEVIVVDKPGPPIG--PLTPTEVTAHTVSLSWKPPQDNGGAEVTGYVVERPTP 6000

Query: 863  SITWYRN 869
            + T+ R+
Sbjct: 6001 TTTYERS 6007



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 833  PLFINRFQEITVKEKGTIKLV--ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            P  I+R   I V+ K     V    V+  PVP   W  N + I PS      ++  N +L
Sbjct: 4677 PPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRYNDYNTKL 4736

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             +T    E  SG Y  VA N+ GK S    V +
Sbjct: 4737 RVTGATRE-QSGTYTIVAENANGKDSADVEVIV 4768



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 7/134 (5%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEKEPPQVIEPL--KSMIVRQGESV 752
            ++ N+ + QE  + V A+N  G+       + IK      P++   L  + M V  GE  
Sbjct: 6513 RVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCISFRAPKITSDLSIRDMTVIAGEEF 6572

Query: 753  ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKAE 808
             ++   + +P+P + W        P   +    D   +S + + K  K  D G YT+K  
Sbjct: 6573 TITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYTIKLT 6632

Query: 809  NSEGIAETSAVITV 822
            NSEG    S  + V
Sbjct: 6633 NSEGADSGSCKVNV 6646



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 6/171 (3%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++ LQ+  V       LE E   + T    W R+G  +         E +G   KL+
Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRITSEESKGKF-KLF 7012

Query: 1076 IRNTSVHDEGEYSCILRDESCTA-EVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132
            I +    DEG+Y+C+  +++  A  +  V++  PP I        + +G+    +I  T 
Sbjct: 7013 ISDMWEVDEGDYACVAANDAGQATSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFTG 7072

Query: 1133 GDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
               L V   ++G  ++ S  ++ T+  +   + I +    DAG+Y+  V N
Sbjct: 7073 DLPLDVTLSQNGLPVEESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVKN 7123



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 21/163 (12%)

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEW--LVTAVIEGIPPP-EVIWYKNGNKLENDKEYNI 1621
            VG +  PVI     D++QK+   ++    +  V+EGIPPP ++ ++K   ++ +   Y I
Sbjct: 1153 VGKEGPPVIV----DVQQKYTAVEDQNGYIDLVVEGIPPPTKIKFFKGITEIIDGGRYKI 1208

Query: 1622 TTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
             T+ +T+ I   I++ K +    Y +   N  G  S E+   V D        +  R + 
Sbjct: 1209 HTEGETNTITLCIRKTKANDEGHYKVIVGNEHGEDSAEMDFYVSDASG-----MDFRAML 1263

Query: 1680 RESVTIEWKPPLDD---GGLELT----KYAIEKHEPDNNRWIK 1715
            ++    +WK   +D   G L+ T    K  + K E     W+K
Sbjct: 1264 KKKKYAKWKKDNEDPDWGDLKETEKEVKPQLRKVERKQEMWVK 1306



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 3/122 (2%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            + + A N  G  E S              P +     +++T+     +K    ++  P P
Sbjct: 4353 FRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKYDCDISGEPPP 4412

Query: 863  SITWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            + +W      +  S  +T  N D  N +LVI +     DSG+Y   A+NS+GK     RV
Sbjct: 4413 TASWTYEGRKLEASRHVTIANID-YNSKLVIRDT-VRADSGEYVITATNSSGKDQVTVRV 4470

Query: 922  TI 923
            T+
Sbjct: 4471 TV 4472



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 7/133 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEA--SLPIVL-KIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            +  + + +E  + V+AVN  G +  S P  L KI+    +P   +  ++   VR GE   
Sbjct: 6218 VLGLTELEEYYFRVIAVNEVGPSAPSRPSALIKIEEQANKPRIDLSAVRDPPVRAGEDFS 6277

Query: 754  LSAQVVGNPRPTITWCKNNKPVK--ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAEN 809
            +     G P+PT TW  +++ +   A P   +   D +   I+   +  D G Y L+ +N
Sbjct: 6278 IHVPYTGFPKPTSTWYHDDEDINIGADPRIHEKLTDDYCAMIVTNAQRSDTGPYKLRLQN 6337

Query: 810  SEGIAETSAVITV 822
              G    S  + V
Sbjct: 6338 PSGFDSVSLNVRV 6350



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P FV+ L+        +V  EC+ EG P P   W R    +          +      L 
Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRITS-EESKGKFKLF 7012

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I +++  D G + CVA N AG A+S   + +  P
Sbjct: 7013 ISDMWEVDEGDYACVAANDAGQATSIAHVKIGNP 7046



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 632  IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            +PP   +K      +  GS +  +C +   P P  +W ++G ++    ++++A   D   
Sbjct: 4380 LPPKIDRKNLRDVTISAGSMLKYDCDISGEPPPTASWTYEGRKLEASRHVTIA-NID--- 4435

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            Y S L I +  +   G Y + A N  G+  + + + + T +  PP+   P+K   VR
Sbjct: 4436 YNSKLVIRDTVRADSGEYVITATNSSGKDQVTVRVTV-TDKPSPPE--GPIKVSDVR 4489



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +  +  + G P+P   W ++   ++PS+   M    D+   L + +   ED+GTFT 
Sbjct: 5879 GEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDH-CRLFVDKARREDSGTFTI 5937

Query: 584  VAKNAAGFASSTTELIV 600
             A+N  G  S+  E+IV
Sbjct: 5938 TAENPYGKDSADIEVIV 5954



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G   + +  +   P P+  WL   ++I P    ++        Y + L++T   + Q GT
Sbjct: 4693 GQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRYND----YNTKLRVTGATREQSGT 4748

Query: 708  YTVVAVNREGE--ASLPIVLKIKTGEKEPP 735
            YT+VA N  G+  A + +++  K G  + P
Sbjct: 4749 YTIVAENANGKDSADVEVIVLDKPGTPQGP 4778



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 1/87 (1%)

Query: 514  EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
            + LR      GS ++++C + G P P  +W  +   ++ S+   +   D N + LVIR+ 
Sbjct: 4387 KNLRDVTISAGSMLKYDCDISGEPPPTASWTYEGRKLEASRHVTIANIDYN-SKLVIRDT 4445

Query: 574  FPEDAGTFTCVAKNAAGFASSTTELIV 600
               D+G +   A N++G    T  + V
Sbjct: 4446 VRADSGEYVITATNSSGKDQVTVRVTV 4472



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 9/162 (5%)

Query: 670  KGEEIVPDENISVAIESDMHMYCSV-----LKITNVKKFQEGTYTVVAVNREGEA--SLP 722
            K ++ +PD  ++  ++ D+            K+  +K   E  + VVAVN+ G +  S P
Sbjct: 2532 KKDKFMPDWEVAAELKQDVIQPLKPGTPVETKVGGLKHRAEYQFRVVAVNKAGNSPESEP 2591

Query: 723  IVLKIKTGEKEPPQVIEP-LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
                +   +   P++    LK   ++ G +V     + G P P++ W    + VK    +
Sbjct: 2592 TDYHLVKHKALKPRIDRTHLKQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIE 2651

Query: 782  -SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
              + D ++   +   K K  G Y + A N +G  E +  I V
Sbjct: 2652 IVNVDYNTKFNMIDAKRKQTGTYKIIATNRDGKDEAAVEIVV 2693



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 708  YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRP 764
            + VVA+N+ G  E S P    +   +  PP++    +  + V+ G+++ L   VVG P  
Sbjct: 4946 FRVVAINKAGPGEPSEPTKPHVARPKNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPA 5005

Query: 765  TITW-CKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            T  W  ++N   P   L   ++    +I I   K+  D G +TL A N  G    +  IT
Sbjct: 5006 TKQWRVRDNDLYPSDRLSIINEDYMTTIKITDCKR-SDSGAFTLNARNKNGEDTCTVNIT 5064

Query: 822  VEEPTEENAEPPLFIN 837
            V +       P  F N
Sbjct: 5065 VLDVPGAPEGPVKFSN 5080



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 5/99 (5%)

Query: 630  EGIPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            + +PP   +       V  G ++ L   +V  P     W  +  ++ P + +S+  E   
Sbjct: 4971 KNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPATKQWRVRDNDLYPSDRLSIINED-- 5028

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
              Y + +KIT+ K+   G +T+ A N+ GE +  + + +
Sbjct: 5029 --YMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITV 5065



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 3/89 (3%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G +  +    +A P+P + W     E++PD  +   ++S  +    V K  + K+   G 
Sbjct: 6569 GEEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNK--SAKRSDIGK 6626

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
            YT+   N EG  S    + +      PPQ
Sbjct: 6627 YTIKLTNSEGADSGSCKVNV-VDRPSPPQ 6654



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 48/205 (23%), Positives = 85/205 (41%), Gaps = 18/205 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  F+K+ K++ V E S ++LEC  V   E ++ W + G+++ PD  I + I  D     
Sbjct: 1488 PFKFTKQLKSKTVTENSKVILECD-VDEAEAEVEWFYGGQKLTPDSKI-LKIMKDGKKRQ 1545

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             V K  ++     G Y+    N + E +  I+++ +   K      + L+  +  + +  
Sbjct: 1546 LVFK--SISMDDAGNYS-CRTNAD-ETTCEIIVQYENKFK------KKLQDQMTYERQPA 1595

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
                ++V +P   + W  N K V        +  G  H + I+K      EG       N
Sbjct: 1596 TFEVELV-DPNAPLQWFINGKEVTEGDNYEFQKKGGVHRL-IIKEAATAHEGEIKAVCGN 1653

Query: 810  SEGIAETSAVITVEEPTEENAEPPL 834
             E   + S V   E+P     E P+
Sbjct: 1654 LETACQLS-VGEGEKPPSIKPEEPI 1677



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNC 1366
            A PQP+ EW      +K+    K ++      +     L +  VE  DAG+YK++ +N  
Sbjct: 32   ASPQPSIEWFREDTPVKESSRVKITVKPGKGGNIHDVQLILDDVEEEDAGLYKVKAKNKY 91

Query: 1367 GHADVEMNVTILDKPSP 1383
            G     +N+       P
Sbjct: 92   GEVSASINLNFSPNEQP 108



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  G  I ++  L   P+P   W  KG+++ P +  S+   SD   +C  L +   ++  
Sbjct: 5876 VRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSD---HCR-LFVDKARRED 5931

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735
             GT+T+ A N  G+ S  I + I   +  PP
Sbjct: 5932 SGTFTITAENPYGKDSADIEV-IVVDKPGPP 5961



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F ++L+ K   + S V  EC V+     ++ WF     + P         D     LV +
Sbjct: 1491 FTKQLKSKTVTENSKVILECDVDE-AEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFK 1549

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             +  +DAG ++C   NA     +T E+IV+
Sbjct: 1550 SISMDDAGNYSC-RTNA---DETTCEIIVQ 1575



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 36/137 (26%), Positives = 63/137 (45%), Gaps = 7/137 (5%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEP--LKSMIVRQGESV 752
            K+ ++ + +   + V AVN+ G++         T + K    VI+   L+++ VR G+ +
Sbjct: 3750 KVNDLTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTNLENITVRAGQMI 3809

Query: 753  ILSAQVVGNPRPTITWCKNN-KPVKALP-TKSDGDTHSITILKPKKVK-DEGVYTLKAEN 809
                 V G P P  TW  N  +     P  K D + H   I+     +   G + +KA+N
Sbjct: 3810 KFDCNVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADN 3869

Query: 810  SEGIAE-TSAVITVEEP 825
            + G  E T  VI +++P
Sbjct: 3870 TAGHDEVTIEVIVLDKP 3886


>UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whole
            genome shotgun sequence; n=11; Euteleostomi|Rep:
            Chromosome undetermined SCAF15134, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 8402

 Score =  244 bits (598), Expect = 2e-62
 Identities = 179/686 (26%), Positives = 291/686 (42%), Gaps = 32/686 (4%)

Query: 1287 PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            PP+++   D  +   ++ G  + + + ++  P P   W      +      +   D    
Sbjct: 2686 PPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQL 2745

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
            S+ I   +  DAG Y L LEN+ G     ++V +LD P  P    + +I   S+ + W+ 
Sbjct: 2746 SIDI--CDKYDAGKYILTLENSAGTKSAFVSVKVLDTPGAPVNLTVKDIKRESVTLTWEP 2803

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            P   G + I  Y+VE +E     + +V N  TKT   + +LK  + Y FR  A NE  + 
Sbjct: 2804 PLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVG 2863

Query: 1463 DASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            +A+ET +  K     +   K+    V K   + + E  +    + I G   + +     +
Sbjct: 2864 EAAETEDSVKTSEPPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEE 2923

Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
                 TAK T E                 ++  AFN+ G  +   +         TI + 
Sbjct: 2924 WTVATTAK-TCEG----TVTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATI-HP 2977

Query: 1579 DIKQKHKV-----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
              K          G+   +   + G P P++ W K+G  L+     N++  + ++ I IK
Sbjct: 2978 AFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIYIK 3037

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
            +  +  + KYTI A+N+ GT++ E+T+ + DKP  P GPV + E+S   VT+ W+PP   
Sbjct: 3038 DANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNYVTLSWEPPEYT 3097

Query: 1694 GGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
            GG ++  Y +EK +     W I  A + R   T  + KL    EY FRV A+N  G S A
Sbjct: 3098 GGCQINNYIVEKRDTTTTAWQIVSATIAR--TTIKVTKLKTGIEYQFRVSAENRYGKSPA 3155

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK- 1811
            + S  +V +     P              +++ + W     NGGSP++ Y +E K++   
Sbjct: 3156 IVSPAVVAQYPFTQP-VAPGTPTISAATKDTMTVEWKAPTNNGGSPVLGYHIERKEKNSL 3214

Query: 1812 KWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
             W             +  +L     Y+FR+YA N  G S      +         PP  P
Sbjct: 3215 LWTKLNKLLIPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISESTVARDPCDPPGTP 3274

Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929
                  E T   VTL+WT P+ +GGS IT Y++E K      W K         +  +  
Sbjct: 3275 E---AIEITRNHVTLQWTRPQYDGGSAITGYVVERKKHPDTRWMKASFTNIIDTQFTVTG 3331

Query: 1930 IKEKDEIIFRISAENTVGV-SLPTES 1954
            + E     FR+ A N   + S P+ES
Sbjct: 3332 LTEDCVYEFRVIARNAASICSRPSES 3357



 Score =  241 bits (591), Expect = 1e-61
 Identities = 170/665 (25%), Positives = 279/665 (41%), Gaps = 23/665 (3%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +K GS  T+ V ++  P P   W  N   +               S+++++    D+G Y
Sbjct: 4862 VKDGSSFTMTVPFKGKPVPTVTW--NKPDVDLRVRAVIDTTDTFTSISLEQANREDSGKY 4919

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             + L N  G   + +NV +LD P  P +  + ++  SS  + WD PEN G   +  Y+V+
Sbjct: 4920 TVTLSNVAGTTSLALNVRVLDSPGAPARVEVKDVTKSSATVTWDTPENEGGGPVKNYLVD 4979

Query: 1419 YQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +E     W  + +     T  + NL+    Y FR    NE      +ET E  K+   T
Sbjct: 4980 IREASKKGWTRLTDTCHRLTYKVTNLQEGGVYYFRVTGENEYGTGLPAETKEGTKITGIT 5039

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGK----KLKTAKA 1527
            K+       P   +T    E + L  +     GG  +    V     G+    K  T K 
Sbjct: 5040 KMIEKPSPPPKLGVTDVTKESVTLAWVKPEQDGGSRITGYLVEALEKGQEKWVKCGTTKF 5099

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-K 1585
             +                       F++  E+  + VV  Q + P I + N      + +
Sbjct: 5100 IHFTVSGLRENAEYFFRVRAENHAGFSETKEMVNAVVVKDQFECPEINMKNFPHNTVYVR 5159

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
             G        + G P P+V   K+  +L++   +N      +  I ++E     S +Y I
Sbjct: 5160 AGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVAGDSGRYDI 5219

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
             ASN++GTS   + + V D+PS P+GPV + +++ +SV+++W  P  DGG  +T Y I+K
Sbjct: 5220 TASNSSGTSKSFLNIVVLDRPSAPQGPVELFDVTEDSVSLKWLAPAYDGGSPITNYIIQK 5279

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
             E     W+ V+       T  I KL    EY FR+ A+N  G SE ++S P+ +     
Sbjct: 5280 RETTTANWMDVSSAVARC-TMKIMKLTTGLEYQFRIRAENKYGISEHIDSPPVSVNLPYT 5338

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA 1824
            VP           +  E + + W   + +GGS +  Y +++K +    W+          
Sbjct: 5339 VPE-APSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVNKTVIRAT 5397

Query: 1825 RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
              +  +IN    Y+F++ A N  G S+     D +       P   P N  + + T  +V
Sbjct: 5398 HFKITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEP---PLNLRIIDITKNTV 5454

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            TL W +P  +GGSPIT YIIE K      W K      +     +  + + +   FR+ A
Sbjct: 5455 TLSWEKPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQDETYEFRVMA 5514

Query: 1943 ENTVG 1947
             N VG
Sbjct: 5515 RNAVG 5519



 Score =  233 bits (569), Expect = 5e-59
 Identities = 180/706 (25%), Positives = 306/706 (43%), Gaps = 43/706 (6%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            D  +   ++  + + L V  +  P+P  +W      + +    +  + S    L I  V+
Sbjct: 3777 DLRKIVNVRATATLRLFVTIRGKPEPEVKWSKADGTLNE--RAQIEVTSSYTMLVIDNVD 3834

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              D G Y + LEN  G     +NV +LD PS P    + ++  +S+++CW+ P   G + 
Sbjct: 3835 RFDTGKYVVTLENLSGSKTAFVNVRVLDSPSAPTNLEVKDVKQNSVSLCWEPPLIDGGAK 3894

Query: 1412 IIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            I +Y+VE +E     + SV  N  +    I +L+    Y FR  AVNE+ +     +T+ 
Sbjct: 3895 ISHYIVEKREQKRMAFTSVCTNCVRNSYIISDLQQGGRYYFRVLAVNELGVG-LPASTDQ 3953

Query: 1471 YKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVT--WYRDGKKL 1522
             KV    +   K+    V +    ++ E  E+   + I   +   QPK    W    + +
Sbjct: 3954 VKVSEPPLPPGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCE-V 4012

Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG------IQQKPVITIS 1576
            K  +AT +                 ++ IA ND G+ +   ++       I  +P+I + 
Sbjct: 4013 KALEATVDG--------LSTGEEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLL 4064

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
             +    K   GD+  +    +G P PEV W K+G  L+     N+ T + +S I IK+  
Sbjct: 4065 FDTYSVK--AGDDLKIDVPFKGRPQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDAT 4122

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            +  + KY I  +++ GT S  + + + DKP  P   + + E+S + V++ W PP  DGG 
Sbjct: 4123 KDDTGKYEITLTSSVGTKSAVIAVIILDKPGPPSN-IKVDEVSADFVSLSWDPPTYDGGC 4181

Query: 1697 ELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            ++  Y +EK +     W I  A V R   +  + +L +  EY FR+ ++N  G S A++S
Sbjct: 4182 QINNYVVEKRDTTTTTWQIVSATVAR--TSIKVTRLTQGTEYQFRIASENRYGKSSAIDS 4239

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814
             P+V +   + P                + + W     +GGSP+  Y +E K++    W 
Sbjct: 4240 VPVVAQYPFEPPGPPTNLHVAHA-SKYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWT 4298

Query: 1815 XXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
                      + +         YQFR+YA N  G      + D +       P   PRN 
Sbjct: 4299 KVNRGLLTENQFKMTGTEEGLMYQFRVYAENIAGIGPCTKASDAVA---ARDPCEPPRNL 4355

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE 1932
             V+  T  SV+L W +PE +GG  IT +I+E K +    W K            +  + E
Sbjct: 4356 RVTNITRTSVSLFWDKPEYDGGVKITGFIVERKELPNGRWLKCNFTNLQDTYFDVTGLTE 4415

Query: 1933 KDEIIFRISAENTVG-VSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
              +  F + A+N+   +S P+ES      K      PPT  LE ++
Sbjct: 4416 DVQYEFHVIAKNSAELLSAPSESTGPVTVKDDV--DPPTIILEDKL 4459



 Score =  219 bits (536), Expect = 5e-55
 Identities = 214/890 (24%), Positives = 360/890 (40%), Gaps = 40/890 (4%)

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTL 1244
            TA   V+ P         + ++V A     L   +  + +    W+K    +E++ +  +
Sbjct: 2289 TAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARAEI 2348

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFP-PKIVDYEREYRIKR 1301
             +   K  L+++     D  +YT VL +   T  +   V+V++ P P           + 
Sbjct: 2349 KNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSNVTEE 2408

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
               ++ L            +I+  +   +   T  S D  +    + K+   +  I+++ 
Sbjct: 2409 KCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVTKLLKGNEYIFRVM 2468

Query: 1362 LENNCGHAD-VEMNVTILDKPS-PPGKPNILEIDS---SSINICWDEPENTGNSTIIYYV 1416
              N  G  + +E    I+  P  PPG P  LEI +    S+ +CW+ PE  G STI+ Y+
Sbjct: 2469 AVNKYGVGEPLESVPVIMRNPFVPPGPPQELEITNITRDSMTVCWNRPETNGGSTIVGYI 2528

Query: 1417 VEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            +E ++     W   + + +T  +  +  L  +  Y FR  A N   +      T  +K  
Sbjct: 2529 IEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXXPT--FKPG 2586

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDI-ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
              T   +  V+    +I+   +  I +  C   G    ++T   + + +     T  N  
Sbjct: 2587 CPT--NAHVVDTRKDSISLSWHRPIYDGGCEIQGY-AVEITKADEEEWVICTPPTGVNAT 2643

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-----KPVITISNEDIKQ--KHKV 1586
                           +  A N  G  E + V G+ +     +P   I + D+++    + 
Sbjct: 2644 KFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRA 2703

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G    +    +G P PE+ W K   +L    +  + T E  S + I    +  + KY + 
Sbjct: 2704 GGSMRICIPFKGRPTPEIRWAKEDAELPG--KVQVETGEDYSQLSIDICDKYDAGKYILT 2761

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
              N+AGT S  V++KV D P  P   + +++I RESVT+ W+PPL DGG  +  Y +EK 
Sbjct: 2762 LENSAGTKSAFVSVKVLDTPGAPVN-LTVKDIKRESVTLTWEPPLIDGGARIKNYLVEKR 2820

Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
            E     +  V D      +Y +  L E   Y FRV+A+N  G  EA E+E  V KT+   
Sbjct: 2821 ESTRKVYSNV-DNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVGEAAETEDSV-KTS--E 2876

Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR 1825
            P           +   +   +W   + +GGS I+ Y +E++  G ++W            
Sbjct: 2877 PPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEEWTVATTAKTCEGT 2936

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            +  LS    Y FR+ A NE G S P      +T       P+    F  + S      LK
Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTF-NTYSIQNGENLK 2995

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945
               P      P   +  + + +K  +   +     S   + I++  + D   + I+A N+
Sbjct: 2996 IDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIY-IKDANKDDAGKYTITATNS 3054

Query: 1946 VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005
            VG +   E   + L+K    P PPT P++I  V SN V  SW  PE+ GG  +  Y +  
Sbjct: 3055 VGTA-TEEITVIILDK----PGPPTGPVKIEEVSSNYVTLSWEPPEYTGGCQINNYIVEK 3109

Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            RD T T W  V      T    +  L     Y  R+ A N  G S  + S
Sbjct: 3110 RDTTTTAWQIVSATIART-TIKVTKLKTGIEYQFRVSAENRYGKSPAIVS 3158



 Score =  219 bits (535), Expect = 7e-55
 Identities = 199/803 (24%), Positives = 339/803 (42%), Gaps = 56/803 (6%)

Query: 1189 LTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFT 1243
            + ++EP I  T  L      L+        T++IP        V W  ++  +++T++  
Sbjct: 7192 VVIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVIWKLEEMKLKETDRIL 7251

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302
            + +  ++ TL++R     D  +Y  VL ++       V V V   P       E      
Sbjct: 7252 IRTTDERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVTVAVVGRPSPPTGPVEVSGVSS 7311

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYK 1359
               TL     A     D   + + I++K +    S   ++S     TIK    T    Y 
Sbjct: 7312 ESCTLSWSEPADDGGTD---ITNYIVEKRESGSASWQVVNSSVKRTTIKVTHLTKYMEYT 7368

Query: 1360 LRL--ENNCGHA-DVEMNVTILDKP----SPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
             R+  EN  G +  VE    ++  P    SPP +P+++ + +++I I WD P   G S I
Sbjct: 7369 FRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRPDVVSVSANAIGIKWDVPYADGGSKI 7428

Query: 1413 IYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
              Y +E +E +T  W+    +   +    + NL     Y+FR YA+N   I+  S+ +E 
Sbjct: 7429 TGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQFRVYAMN---IAGLSKASEA 7485

Query: 1471 YKVIKETKIQSPTVEKPLKNIT--------TEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
             + I       P  +  + +IT        T P  D   + I G V + KV    +    
Sbjct: 7486 SRPILALNPVDPPGKPEVTDITRSSASLCWTVPFNDGG-SKIVGYVVERKVYSADEWDDN 7544

Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHG----EVETSCVVGIQQK---PVI 1573
            +  K  Y                  Y+   IA N  G      E+S  V  + +   P  
Sbjct: 7545 RWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGVHSAASESSGPVTCKDEYSPPRA 7604

Query: 1574 TISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             + ++ + +   +  G + ++   + G P P V W K    LE  ++Y++T     ++  
Sbjct: 7605 ELDSKLVGETVTISAGSDLVLDGAVGGKPEPTVYWSKGDKILELGEKYSLTYTATRAMAV 7664

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            IK   RS + +Y +   N +G  +  V LKV D P  P   +++  ++ E  T+ WK PL
Sbjct: 7665 IKNCDRSDTGRYCLTVKNASGVKTAWVNLKVLDTPGPPADKIVISRVTEEKCTVSWKIPL 7724

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            +DGG  +T Y +E+ E     W+ V + +    +    +L +N EY+FRV   N  G   
Sbjct: 7725 EDGGDSVTHYVVERRETSRLNWVLV-EAECKTLSCVSSRLIKNNEYIFRVRGVNKFGPGV 7783

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
             LESEP++ + A  +PS          +  E V I W   E +GGS I +Y V+ +++  
Sbjct: 7784 PLESEPVIARNAYTIPS-QPGTPETTAVGKEHVIIEWLKPESDGGSEISNYIVDKREKSS 7842

Query: 1812 -KW---KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK---TLT 1864
             +W              ++  L   + YQFR+ A N  G S P  +   I       T  
Sbjct: 7843 TRWTRVNKTYTIYDTRLKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPA 7902

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            PPS PR   ++++T  S+++ WT P  +GGS ++ Y++E      + W +  T     +E
Sbjct: 7903 PPSVPR---ITDTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNE 7959

Query: 1925 HCIENIKEKDEIIFRISAENTVG 1947
                 +    +  FR++A N+ G
Sbjct: 7960 FVAAGLAANKKYRFRVAALNSKG 7982



 Score =  213 bits (520), Expect = 4e-53
 Identities = 193/769 (25%), Positives = 331/769 (43%), Gaps = 48/769 (6%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
            +V+W K   +++ T +  +++      ++I+  T+DD  +Y   L  +  T    + V+ 
Sbjct: 4089 EVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIAVI- 4147

Query: 1286 FPPKIVDYEREYRIKRGSDVTL-LVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSA 1343
                I+D        +  +V+   V     P   D    +N+ +++K   T  +    SA
Sbjct: 4148 ----ILDKPGPPSNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRDTTTTTWQIVSA 4203

Query: 1344 SL---TIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDK-P-SPPGKPNILEIDSSS 1396
            ++   +IK    T    Y+ R+  EN  G +    +V ++ + P  PPG P  L +  +S
Sbjct: 4204 TVARTSIKVTRLTQGTEYQFRIASENRYGKSSAIDSVPVVAQYPFEPPGPPTNLHVAHAS 4263

Query: 1397 ---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451
               + + W+ P + G S +  Y +E +E ++  W  V    +T+ Q  +   +    Y+F
Sbjct: 4264 KYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWTKVNRGLLTENQFKMTGTEEGLMYQF 4323

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQ 1510
            R YA N   I+     T+    +       P     + NIT T  +   +     GGV  
Sbjct: 4324 RVYAEN---IAGIGPCTKASDAVAARDPCEPPRNLRVTNITRTSVSLFWDKPEYDGGV-- 4378

Query: 1511 PKVTWYR-DGKKLKTA---KATYENRXXXXXXXXXXXXXXXYK--CIAFND----HGEVE 1560
             K+T +  + K+L      K  + N                Y+   IA N         E
Sbjct: 4379 -KITGFIVERKELPNGRWLKCNFTNLQDTYFDVTGLTEDVQYEFHVIAKNSAELLSAPSE 4437

Query: 1561 TSCVVGIQQK--PVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            ++  V ++    P   I  + ++Q    + G+   + A I G P P V W K+G ++E  
Sbjct: 4438 STGPVTVKDDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPVVSWSKDGKEIEAK 4497

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
                IT+    + + +++  R  S +Y +   N AGT SV V  KV D+P  P GP+ + 
Sbjct: 4498 ARCEITSTNFNTTLIVRDAIRRDSGQYVLTLHNVAGTRSVAVNCKVLDRPGPPSGPLAIT 4557

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
             ++ E  ++ W PP ++GG E+  Y +EK E     W  V   D    T  + KL +  E
Sbjct: 4558 GLTAEKCSLAWGPPQENGGAEIMHYIVEKRETSRLAWTLVYG-DMKATTCKVTKLLKGNE 4616

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y+FRV   N  G  E LESEP        VP+          + +E++ I W     +GG
Sbjct: 4617 YIFRVRGVNKYGDGEPLESEPTKAMDPFTVPT-PPTNVQVTAVTSEAMTICWERPVSDGG 4675

Query: 1797 SPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTS 1853
            S I  Y +E +++ G +W           R++   L     Y++R++A N  G S P   
Sbjct: 4676 SSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRVFAENSAGLSAPSIP 4735

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
               I        PS P    + +ST  +VTL W +P  +GG+P+T Y +E++      W 
Sbjct: 4736 CPLIKAEDPQFLPSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPVTGYRVEYRKTLDDEW- 4794

Query: 1914 KIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             +V V  + + E  +  +    E +F I + N +GVS P+     ++ K
Sbjct: 4795 -VVAVQNTKNTEFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDKQVAK 4842



 Score =  212 bits (518), Expect = 8e-53
 Identities = 174/695 (25%), Positives = 294/695 (42%), Gaps = 35/695 (5%)

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
            V    +Y  + G DV + +  +  P PN  W    + +        S   ++ +L I KV
Sbjct: 5943 VQMTTQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTERATTLVIPKV 6002

Query: 1351 ENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
               D G Y L +EN  G    V +++ +LD PS   K  +  +    + + W+ P   G 
Sbjct: 6003 TRDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLLVKNVSRGELTLSWEAPVIDGG 6062

Query: 1410 STIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
              +  Y+VE +      + +       T   +  L  + +Y FR  A NE  + D  ET+
Sbjct: 6063 CPVTNYIVEKKGSTMKAYQVITAECANTSYKVSGLDIDVAYFFRVSAENEYGVGDPCETS 6122

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLK--- 1523
                 ++ T+   P  +  + + +T+ +  ++ T     GG     +T Y   KK +   
Sbjct: 6123 G---PVRATETPGPVKDLVMLD-STKGSVTLQWTRPDHDGG---SHITDYIIEKKAQEEN 6175

Query: 1524 --TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQQ---KPVITIS 1576
              T  AT + R               ++  A N+ G  + S +  + +Q     P   +S
Sbjct: 6176 SWTLAATCK-RCSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLS 6234

Query: 1577 N-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
            +  + +   +VG    +    +G P P + W K+   L+  ++    T +  + + ++  
Sbjct: 6235 DYPNAELAVRVGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGA 6294

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
            K+ H+ +YT+   N    +  ++ +     PS P GP+   EI  +S+ I W  P +DGG
Sbjct: 6295 KKEHAGQYTLVLDNRTIKNYFDINVITLGPPSVPVGPIRFDEIKAQSIIISWDEPKEDGG 6354

Query: 1696 LELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
             E+T Y++EK E     W  V + V R   T+ I  L +  +Y FRV A+N  G S  L 
Sbjct: 6355 GEITCYSVEKRETSQANWKMVCSSVVR--TTFKIPNLVKGTQYQFRVRAENKYGVSNPLT 6412

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW 1813
            S  +V +     P           + ++ + I W   + +GGSPI+ Y VE K      W
Sbjct: 6413 SLDVVAQHQYK-PPGPPGKPVAYNVTSDGMTIRWEAPDFDGGSPIMGYHVEKKDRNSLMW 6471

Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
            +            RI  L     Y FR+YA N  G S P +   K  +   ++P   P  
Sbjct: 6472 QKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLS-PVSEQSKHAL--AISPVDPPGT 6528

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
             V  + T  SVTL+W  P+ +GGS I  Y +E +  +GK W +      S  +  +  + 
Sbjct: 6529 PVCIDVTRDSVTLQWDTPKKDGGSKIVGYSVERRQGRGK-WLRCNFTDVSETQFTVTALS 6587

Query: 1932 EKDEIIFRISAENTVG-VSLPTESQSVRLEKHATV 1965
              D   FR+ A N VG +S P+ S    + K  ++
Sbjct: 6588 PGDRFEFRVIARNAVGTISPPSNSSGYIMTKDESI 6622



 Score =  207 bits (506), Expect = 2e-51
 Identities = 189/722 (26%), Positives = 306/722 (42%), Gaps = 61/722 (8%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P  PG P+   +  +SI +CW  P + G + I  Y++E +E  +  W+ V +   IT+ +
Sbjct: 6784 PDAPGTPDATHVTGNSITMCWTRPRSDGGNEIKQYILERREKKSLRWVKVSSKRAITELR 6843

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITTEPN 1496
              + NL   + Y FR  A N   +  AS T+  +K  + T   S PTV K + +  T+ +
Sbjct: 6844 HRVTNLTEGNEYEFRVMAENGAGVGPASSTSRLFKCREPTSAPSAPTVIKVIDS--TKSS 6901

Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYEN-----RXXXXXXXXXXXXXXXYKC 1550
              IE T  +F G  +  + +  D  K    +    N                     ++ 
Sbjct: 6902 VTIEWTKPVFDGGMEI-IGYNIDMCKASLEEWHRVNSQICIHTRYTAKGLVPGELYKFRV 6960

Query: 1551 IAFNDHGEVETSCVVG-IQQKPVITISNEDI----KQKHKVGDEWLVTAVI--EGIPPPE 1603
             A N  GE E S +   +Q    +T    DI    KQ H V +   VT  +   G P P 
Sbjct: 6961 SAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFKQTHTVKNGGTVTLQVAFRGKPAPL 7020

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
              W K   +L    + N T    T  + I+   R  + KYT+   N +G  S+  T+KV 
Sbjct: 7021 ATWSKADGELPIMADVNTTNTSST--LTIEGCTRYEAGKYTLSLENNSGRKSITFTIKVL 7078

Query: 1664 DKPSKPEGPVIMREISRESVTIE---------------------WKPPLDDGGLELTKYA 1702
            D P  P GP+  ++++   +  E                     W  P  DGG  +  Y 
Sbjct: 7079 DTPGPP-GPIAFKDMTEPIIATEEPAPPKRLDVIDTTSSTASLVWLKPEHDGGSRIRGYV 7137

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
            +E     +++W+   +  + ++   ++ L EN EY FRV A+N  G SE   +   +VIK
Sbjct: 7138 VEYRAKGSDQWLLSGET-KSLKML-VEGLIENREYDFRVKAKNDAGISEPQGTFGSVVIK 7195

Query: 1762 TALDVPSXXXXXXXXXXIDNE--SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX 1818
                 P+          I  +  + +    P        +I    E+K +E  +      
Sbjct: 7196 EPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVIWKLEEMKLKETDRILIRTT 7255

Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   ++    + + ++ +   N  G    +T    + +G+  +PP+ P    VS  +
Sbjct: 7256 DERTTLLVRDSKRSDSGKYYLVLENSAGVKT-FTVTVAV-VGRP-SPPTGPVE--VSGVS 7310

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEI 1936
            S S TL W+EP  +GG+ ITNYI+E +     SW     V  SV    I+  ++ +  E 
Sbjct: 7311 SESCTLSWSEPADDGGTDITNYIVEKRESGSASWQ---VVNSSVKRTTIKVTHLTKYMEY 7367

Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996
             FR+ AEN  GVS   ES  V ++     PSPPT P ++  V +N +   W  P  DGG+
Sbjct: 7368 TFRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRP-DVVSVSANAIGIKWDVPYADGGS 7426

Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
             + GY I  ++    +W+   K+      + + +L E   Y  R+YA N  GLS+  E+ 
Sbjct: 7427 KITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQFRVYAMNIAGLSKASEAS 7486

Query: 2057 EP 2058
             P
Sbjct: 7487 RP 7488



 Score =  198 bits (482), Expect = 2e-48
 Identities = 174/664 (26%), Positives = 289/664 (43%), Gaps = 57/664 (8%)

Query: 1323 VNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HAD---V 1371
            + + II+K + T  +   + S  A  T+K ++ T    Y+ R+  EN  G   H D   V
Sbjct: 5272 ITNYIIQKRETTTANWMDVSSAVARCTMKIMKLTTGLEYQFRIRAENKYGISEHIDSPPV 5331

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
             +N+     P  P  P I  +    I + W EP++ G S +  Y ++ ++ ++  W  V 
Sbjct: 5332 SVNLPYT-VPEAPSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVN 5390

Query: 1432 N--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK--ETKIQSPTVEKP 1487
               I  T   I N+     Y F+  A N   +S  S+ ++    I   E  +    ++  
Sbjct: 5391 KTVIRATHFKITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEPPLNLRIIDIT 5450

Query: 1488 LKNITT---EPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXX 1540
               +T    +PN D       GG P   +T Y    ++G   +  KA   N         
Sbjct: 5451 KNTVTLSWEKPNYD-------GGSP---ITGYIIEKKEGSSSRWFKANLTNVTDTRFTVT 5500

Query: 1541 XXXXXXXY--KCIAFNDHGEVET-SCVVG------IQQKPVITISNEDIKQ-KHKVGDEW 1590
                   Y  + +A N  G +   S + G          P I I  E + + K +   + 
Sbjct: 5501 GLNQDETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQEYLSEVKFRAESDV 5560

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASN 1649
             +   I   P P + W+K+G +L+   + +   T E TSV  +++  R +S  Y ++  N
Sbjct: 5561 ELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFESTSVF-LRDTTRLNSGSYEVKVKN 5619

Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
            + G++   V L + DKP  P G +  ++++ +++TI W PP D+GG  +T Y +EK E  
Sbjct: 5620 SLGSACATVKLLIQDKPGPPAGEIQFKKVTADNITIMWSPPADEGGAMVTHYIVEKRETS 5679

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
               W  V++   D     + +L +  EY+FRV   N  G  + LESEP++ K A  VP  
Sbjct: 5680 RVMWSIVSEKLVDC-IVNVPRLIQGNEYIFRVRGVNKYGIGDPLESEPVIAKNAF-VPPS 5737

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KWKXXXXXXXXXAR-- 1825
                     I   ++ + W     +GGS I  Y +E K+E K  +W           R  
Sbjct: 5738 EPSKPKVTMITKSTMTVIWERPALDGGSDIDGYYLE-KREKKSLQWFKVVKGTIRDTRQK 5796

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            +  L  N  YQFR+ A N+ G      + D       +  P +P    V +ST  S+TL 
Sbjct: 5797 VSNLVENNEYQFRVCAVNKAGAGNYSEASDLYRAYDPIDLPGEPSKLRVVDSTKSSITLG 5856

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAE 1943
            W +P  +GGS IT+Y+++    + + W   VT+   V   E+ + ++K      F++SA 
Sbjct: 5857 WEKPIYDGGSEITHYVLDQMNTEEREW---VTINPQVKACEYVVSHLKPGTYYFFKVSAV 5913

Query: 1944 NTVG 1947
            N  G
Sbjct: 5914 NCKG 5917



 Score =  196 bits (479), Expect = 4e-48
 Identities = 176/703 (25%), Positives = 298/703 (42%), Gaps = 60/703 (8%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTS 1439
            PSPP KP I++   +++ + W++P   G + +  Y VEY++    EW ++V+N   T+ +
Sbjct: 4748 PSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPVTGYRVEYRKTLDDEWVVAVQNTKNTEFT 4807

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPN 1496
            +  L   + Y F   ++N++ +S+ S  ++  K + + + + P  E   +  K +  +  
Sbjct: 4808 VVKLTPGAEYVFVIKSINKIGVSEPSPESD--KQVAKEREEEPVFEISNEMRKTLIVKDG 4865

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
                +T  F G P P VTW +    L+      T +                 Y     N
Sbjct: 4866 SSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTSISLEQANREDSGKYTVTLSN 4925

Query: 1555 DHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
              G    +  V +   P     +  +D+  K      W  T   EG  P  V  Y    +
Sbjct: 4926 VAGTTSLALNVRVLDSPGAPARVEVKDV-TKSSATVTW-DTPENEGGGP--VKNYLVDIR 4981

Query: 1613 LENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-------SSVEVT--LKV 1662
              + K +  +T        ++  L+      + +   N  GT          ++T   K+
Sbjct: 4982 EASKKGWTRLTDTCHRLTYKVTNLQEGGVYYFRVTGENEYGTGLPAETKEGTKITGITKM 5041

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             +KPS P   + + ++++ESVT+ W  P  DGG  +T Y +E  E    +W+K       
Sbjct: 5042 IEKPSPPP-KLGVTDVTKESVTLAWVKPEQDGGSRITGYLVEALEKGQEKWVKCGTT--K 5098

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDN 1781
               + +  L EN EY FRV A+N  GFSE  E    +V+K   + P             +
Sbjct: 5099 FIHFTVSGLRENAEYFFRVRAENHAGFSETKEMVNAVVVKDQFECPE-----INMKNFPH 5153

Query: 1782 ESVYITWFPSEKNG----GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR------IQKLSI 1831
             +VY+    + K      G P+   KV + ++  + K                 +++   
Sbjct: 5154 NTVYVRAGSTLKCEIPLMGRPL--PKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVA 5211

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPE 1890
              + ++ I A N  GTS  + +   I +   L  PS P+  V + + T  SV+LKW  P 
Sbjct: 5212 GDSGRYDITASNSSGTSKSFLN---IVV---LDRPSAPQGPVELFDVTEDSVSLKWLAPA 5265

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD---EIIFRISAENTVG 1947
             +GGSPITNYII+ +     +W  +     S    C   I +     E  FRI AEN  G
Sbjct: 5266 YDGGSPITNYIIQKRETTTANWMDV----SSAVARCTMKIMKLTTGLEYQFRIRAENKYG 5321

Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
            +S   +S  V +    TVP  P+ P EI  V    +  +W  P+ DGG+ + GY++ ++D
Sbjct: 5322 ISEHIDSPPVSVNLPYTVPEAPSTP-EITAVTRECITVAWKEPKSDGGSHVFGYHLQMKD 5380

Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
                +W  V K  +    F I +++    Y  ++ A N  G+S
Sbjct: 5381 KNSILWQRVNKTVIRATHFKITNINAGLIYEFKVAAENAAGVS 5423



 Score =  195 bits (475), Expect = 1e-47
 Identities = 108/367 (29%), Positives = 176/367 (47%), Gaps = 7/367 (1%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            G+ +++ A   G P PEVIW K+G +++       + T    +++ +K+  R     + +
Sbjct: 3387 GETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGGHFVL 3446

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            +  N  G   V VT+KV D+P  P+GP+ ++ ++ E   + W  P  DGG  ++ Y IEK
Sbjct: 3447 KLVNVGGVKMVPVTVKVLDRPGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISHYIIEK 3506

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
             E     W  V    + + +Y I KL    EY+FRV A N  G  E LESEP++ +    
Sbjct: 3507 RETSRLSWTMVEPKIQAI-SYKITKLLPGNEYIFRVTAVNKYGVGEPLESEPVIARNPFT 3565

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXX 1822
             PS          I  +S+ +TW   E NGG+ I  Y +E + ++G +W           
Sbjct: 3566 TPS-APSTPEASAITRDSIVLTWERPESNGGADIEGYILEKRDKDGVRWTKCNKKRLNDL 3624

Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
              R+  L+   +Y+F++ A N  G   P    + I +   + PP  P N  V++ +S +V
Sbjct: 3625 RFRVTGLTEGHSYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNPKVTDHSSTTV 3684

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRIS 1941
            +L W+ P  +GG+ IT Y++E K      W       G     + +  ++E  E  FRI 
Sbjct: 3685 SLSWSRPIYDGGANITGYVVEMKEAADDEWVICTPPTGVQATHYTVRKLRENAEYSFRIC 3744

Query: 1942 AENTVGV 1948
            A N  G+
Sbjct: 3745 AVNYEGL 3751



 Score =  191 bits (466), Expect = 2e-46
 Identities = 172/709 (24%), Positives = 293/709 (41%), Gaps = 56/709 (7%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT- 1436
            +D P  P K  +++   SSI + W++P   G S I +YV++    +  EW+++    K  
Sbjct: 5834 IDLPGEPSKLRVVDSTKSSITLGWEKPIYDGGSEITHYVLDQMNTEEREWVTINPQVKAC 5893

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLK---NIT 1492
            +  + +LK  + Y F+  AVN        E  + Y+ ++   I +   ++  ++     T
Sbjct: 5894 EYVVSHLKPGTYYFFKVSAVN---CKGKGEDIKMYQPVQAKDILEEADLDLDVQMTTQYT 5950

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
                 D+E+     G P P VTW R  + +       +NR                  + 
Sbjct: 5951 ARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAA-----DNRYTISSTERATTLVIPK--VT 6003

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGD--------EWLVTAVIEGI 1599
             +D G+       G+ +  ++T+S + +      QK  V +         W    +  G 
Sbjct: 6004 RDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLLVKNVSRGELTLSWEAPVIDGGC 6063

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            P    I  K G+ +   K Y + T E  +   ++  L    +  + + A N  G      
Sbjct: 6064 PVTNYIVEKKGSTM---KAYQVITAECANTSYKVSGLDIDVAYFFRVSAENEYGVGDPCE 6120

Query: 1659 TLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            T         P GPV   +M + ++ SVT++W  P  DGG  +T Y IEK   + N W  
Sbjct: 6121 TSGPVRATETP-GPVKDLVMLDSTKGSVTLQWTRPDHDGGSHITDYIIEKKAQEENSWTL 6179

Query: 1716 VADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
             A   R     C +  L EN    FRV A+N  G S+  +  PI ++  +  P       
Sbjct: 6180 AATCKR---CSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLSDY 6236

Query: 1775 XXXXID---NESVYITWFPSEKNGGSPIIDY-KVEIK-QEGKKWKXXXXXXXXXARIQKL 1829
                +     ++++I   P  K    P+I + K  +  +E +K +           ++  
Sbjct: 6237 PNAELAVRVGQNIHIE-LPF-KGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGA 6294

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTE 1888
                  Q+ +   N   T   Y   + IT+G    PPS P   +   E  ++S+ + W E
Sbjct: 6295 KKEHAGQYTLVLDNR--TIKNYFDINVITLG----PPSVPVGPIRFDEIKAQSIIISWDE 6348

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            P+ +GG  IT Y +E +     +W K+V          I N+ +  +  FR+ AEN  GV
Sbjct: 6349 PKEDGGGEITCYSVEKRETSQANW-KMVCSSVVRTTFKIPNLVKGTQYQFRVRAENKYGV 6407

Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
            S P  S  V  +     P PP  P+   +    + +  W  P++DGG+P++GY++  +D 
Sbjct: 6408 SNPLTSLDVVAQHQYKPPGPPGKPVAYNVTSDGMTI-RWEAPDFDGGSPIMGYHVEKKDR 6466

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
               MW +V    ++  ++ I  L E   Y  R+YA N  GLS   E  +
Sbjct: 6467 NSLMWQKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLSPVSEQSK 6515



 Score =  191 bits (465), Expect = 2e-46
 Identities = 204/812 (25%), Positives = 324/812 (39%), Gaps = 64/812 (7%)

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            ++++ + +K G  VTL V ++  P P   W      +        +  + S++LTI+   
Sbjct: 6994 NFKQTHTVKNGGTVTLQVAFRGKPAPLATWSKADGELPIMADVNTT--NTSSTLTIEGCT 7051

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG---------------------KPNIL 1390
              +AG Y L LENN G   +   + +LD P PPG                     + +++
Sbjct: 7052 RYEAGKYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEPAPPKRLDVI 7111

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
            +  SS+ ++ W +PE+ G S I  YVVEY+   + +W+        +  ++ L  N  Y 
Sbjct: 7112 DTTSSTASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVEGLIENREYD 7171

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGV 1508
            FR  A N+  IS+   T     VIKE +I+       + N  IT + +    +     G 
Sbjct: 7172 FRVKAKNDAGISEPQGTFGSV-VIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGR 7230

Query: 1509 PQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VET 1561
            P PKV W  +  KLK        T + R               Y  +  N  G      T
Sbjct: 7231 PAPKVIWKLEEMKLKETDRILIRTTDERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVT 7290

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
              VVG    P   +    +  +      W   A   G      I  K  +   + +  N 
Sbjct: 7291 VAVVGRPSPPTGPVEVSGVSSE-SCTLSWSEPADDGGTDITNYIVEKRESGSASWQVVNS 7349

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV----YDKPSKPEGPVIMR 1676
            + K  T  I++  L +     + + A N  G S SVE T  V    +  PS P  P ++ 
Sbjct: 7350 SVKRTT--IKVTHLTKYMEYTFRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRPDVV- 7406

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
             +S  ++ I+W  P  DGG ++T Y IEK E +   W++   +      Y +  L E  E
Sbjct: 7407 SVSANAIGIKWDVPYADGGSKITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLE 7466

Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            Y FRV A N  G S+A E S PI+    +D P           I   S  + W     +G
Sbjct: 7467 YQFRVYAMNIAGLSKASEASRPILALNPVDPPG----KPEVTDITRSSASLCWTVPFNDG 7522

Query: 1796 GSPIIDYKVEIK------QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT 1847
            GS I+ Y VE K       +  +W              +  LS   TY++ + A+N  G 
Sbjct: 7523 GSKIVGYVVERKVYSADEWDDNRWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGV 7582

Query: 1848 -SLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESNGGSP-ITNYIIEF 1904
             S    S   +T     +PP ++  + +V E+ + S         + GG P  T Y  + 
Sbjct: 7583 HSAASESSGPVTCKDEYSPPRAELDSKLVGETVTISAGSDLVLDGAVGGKPEPTVYWSKG 7642

Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
              +        +T   +     I+N    D   + ++ +N  GV    ++  V L K   
Sbjct: 7643 DKILELGEKYSLTYTATRAMAVIKNCDRSDTGRYCLTVKNASGV----KTAWVNL-KVLD 7697

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
             P PP   + I  V       SW  P  DGG  +  Y +  R+ ++  W+ V + +  TL
Sbjct: 7698 TPGPPADKIVISRVTEEKCTVSWKIPLEDGGDSVTHYVVERRETSRLNWVLV-EAECKTL 7756

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
                  L +N+ Y+ R+   N+ G   PLES+
Sbjct: 7757 SCVSSRLIKNNEYIFRVRGVNKFGPGVPLESE 7788



 Score =  187 bits (455), Expect = 3e-45
 Identities = 150/576 (26%), Positives = 240/576 (41%), Gaps = 34/576 (5%)

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
            W +P + G S I+ Y +E +E ++  W  +    I   +     L+    Y +R YA N 
Sbjct: 2117 WHKPPSDGGSAILGYHLERKEKNSILWTKINKTLIQDCRFKSTPLEEGIEYEYRVYAENI 2176

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT---CIFGGVPQPKVTW 1515
            V I   S+ +E    + +     P   +P   I T  +  +  T      G +    V  
Sbjct: 2177 VGIGKCSKVSEI--CVAQDPCDPPG--RPEALIVTRHSVKLRWTPPQYDGGSLITGYVVE 2232

Query: 1516 YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE--TSCVVGIQQKP 1571
             RD  + K  KA++ N                Y  + IA N  G +   +     I  K 
Sbjct: 2233 KRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTGSITAKD 2292

Query: 1572 VITISNEDIKQKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             +     +    +      K G+ + + A +EG P P   W+K   ++EN     I   +
Sbjct: 2293 EVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARAEIKNTD 2352

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
              +++ +K+  R    +YT+  +N AGT SV  ++KV D+P   EGP+ +  ++ E  ++
Sbjct: 2353 FKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSNVTEEKCSL 2412

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
             W PP  DGG  ++ Y I+K E     W  V+  D     + + KL +  EY+FRV+A N
Sbjct: 2413 SWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSS-DCGATMFKVTKLLKGNEYIFRVMAVN 2471

Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
              G  E LES P++++    VP           I  +S+ + W   E NGGS I+ Y +E
Sbjct: 2472 KYGVGEPLESVPVIMRNPF-VPPGPPQELEITNITRDSMTVCWNRPETNGGSTIVGYIIE 2530

Query: 1806 IK-QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
             + + G +W             R+  L+ +  Y+FR+ A N  G         K      
Sbjct: 2531 KRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXXPTFK------ 2584

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGS 1921
               P  P N  V ++   S++L W  P  +GG  I  Y +E      + W       G +
Sbjct: 2585 ---PGCPTNAHVVDTRKDSISLSWHRPIYDGGCEIQGYAVEITKADEEEWVICTPPTGVN 2641

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
              +  I  + E  E   RI A N +GV  PTE   V
Sbjct: 2642 ATKFTITKLIEHQEYKVRICAINKLGVGEPTEVPGV 2677



 Score =  186 bits (454), Expect = 4e-45
 Identities = 117/389 (30%), Positives = 178/389 (45%), Gaps = 7/389 (1%)

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            A + G P P ++W K+G +LE+  +  I T +  +V+  K+  R     +T+ ASN  G 
Sbjct: 220  ANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPGGF 279

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            +     +KV D+P  P+  + + +++ E   + W  P  DGG ++  + I+K E     W
Sbjct: 280  AKFTFNVKVLDRPGPPDS-LTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAW 338

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
              VA  D       + KL +  EY+FRV+A N  G  E LESEP++      VPS     
Sbjct: 339  TNVA-TDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVICTNPY-VPSDPPGQ 396

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLS 1830
                 I  +S+ + W   E +GGS I  Y +E + + G +W           R  +  L+
Sbjct: 397  PEVTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTVTDLRFKVSGLT 456

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
            +   Y+FR++A N  G S P  S        T+  P  P N  V ++T  S+TL W +P 
Sbjct: 457  LGHEYEFRVFAENNAGLSQPSLSSPFYKAEDTIFMPGPPGNPRVLDTTKSSITLSWNKPV 516

Query: 1891 SNGGSPITNYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
             +GGS IT YI+E    +   WT      G +     I N+KE  E    ISA N  GV 
Sbjct: 517  YDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATSFTITNLKENQEYKINISATNCEGVG 576

Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
             P     +   +   +P       E+R V
Sbjct: 577  EPAAVPGIPKAEDRLLPPEIELGAELRKV 605



 Score =  184 bits (447), Expect = 3e-44
 Identities = 206/896 (22%), Positives = 359/896 (40%), Gaps = 53/896 (5%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249
            +E P +     L + I+V A     + +      T ++ W K+ + +    +     D  
Sbjct: 2684 IEPPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYS 2743

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
            + ++ I  C + D  +Y   L ++  T    + V+V++ P   V+   +  IKR S VTL
Sbjct: 2744 QLSIDI--CDKYDAGKYILTLENSAGTKSAFVSVKVLDTPGAPVNLTVK-DIKRES-VTL 2799

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKP---SIDSKSASLTIKKVENTDAGIYKLRL-- 1362
              +    P  +    + + +++K + T+    ++D+K    + +  +  +  +Y  R+  
Sbjct: 2800 TWEP---PLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLA 2856

Query: 1363 ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
            EN  G    A+ E +V   + P   GK  +  +  ++ +  W++P+  G S I+ Y +E 
Sbjct: 2857 ENEFGVGEAAETEDSVKTSEPPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEM 2916

Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            Q   + EW         + ++  L T   Y FR  A NE   SD           K+  I
Sbjct: 2917 QPAGSEEWTVATTAKTCEGTVTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPV-TAKDATI 2975

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXX-- 1536
              P  +      + +  E++++     G P PK+ W +DG+ LK T +    N       
Sbjct: 2976 H-PAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKI 3034

Query: 1537 -XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLV 1592
                        Y   A N  G       V I  K   P   +  E++   + V   W  
Sbjct: 3035 YIKDANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNY-VTLSWEP 3093

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                 G      I  K        +  + T    T  I++ +LK     ++ + A N  G
Sbjct: 3094 PEYTGGCQINNYIVEKRDTTTTAWQIVSATIARTT--IKVTKLKTGIEYQFRVSAENRYG 3151

Query: 1653 TSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
             S   V+  V     + +P  P  P I    +++++T+EWK P ++GG  +  Y IE+ E
Sbjct: 3152 KSPAIVSPAVVAQYPFTQPVAPGTPTI-SAATKDTMTVEWKAPTNNGGSPVLGYHIERKE 3210

Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDV 1766
             ++  W K+  +      +   +L E  EY FRV A+N  G SEA + SE  V +   D 
Sbjct: 3211 KNSLLWTKLNKLLIPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISESTVARDPCDP 3270

Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR 1825
            P           I    V + W   + +GGS I  Y VE K+    +W           +
Sbjct: 3271 PG----TPEAIEITRNHVTLQWTRPQYDGGSAITGYVVERKKHPDTRWMKASFTNIIDTQ 3326

Query: 1826 --IQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
              +  L+ +  Y+FR+ ARN     S P  S  +IT    +  P    +    + T    
Sbjct: 3327 FTVTGLTEDCVYEFRVIARNAASICSRPSESTGEITAKDEIEAPEATMDSKFKDLTIVHA 3386

Query: 1883 TLKWTEPESNGGSPITN--YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
               +       G P+    ++ + K V   +    V    +     +++    D   F +
Sbjct: 3387 GETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGGHFVL 3446

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
               N  GV +   +  V L++    P PP  PLE++ V +      W  P  DGGA +  
Sbjct: 3447 KLVNVGGVKMVPVTVKV-LDR----PGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISH 3501

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
            Y I  R+ ++  W  V +  +  + + I  L   + Y+ R+ A N+ G+ EPLES+
Sbjct: 3502 YIIEKRETSRLSWTMV-EPKIQAISYKITKLLPGNEYIFRVTAVNKYGVGEPLESE 3556



 Score =  182 bits (442), Expect = 1e-43
 Identities = 173/697 (24%), Positives = 288/697 (41%), Gaps = 39/697 (5%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436
            KP  P   ++++    SI++ W  P   G   I  Y VE  + D  EW+       +  T
Sbjct: 2584 KPGCPTNAHVVDTRKDSISLSWHRPIYDGGCEIQGYAVEITKADEEEWVICTPPTGVNAT 2643

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEP 1495
            + +I  L  +  Y+ R  A+N++ + + +E     K I + +     ++  L K I    
Sbjct: 2644 KFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRA 2703

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
               + +   F G P P++ W ++  +L  K    T E+                Y     
Sbjct: 2704 GGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQLSIDICDKYDAGKYILTLE 2763

Query: 1554 NDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            N  G       V +   P   + ++ +DIK++  V   W    +I+G     +  Y    
Sbjct: 2764 NSAGTKSAFVSVKVLDTPGAPVNLTVKDIKRE-SVTLTW-EPPLIDG--GARIKNYLVEK 2819

Query: 1612 KLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPS 1667
            +    K Y N+  K   +  R+ +LK      + + A N  G    +  E ++K  + P 
Sbjct: 2820 RESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVGEAAETEDSVKTSEPPL 2879

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
               G V +  +++ + +  W+ P  DGG  +  Y IE     +  W  VA   +  E   
Sbjct: 2880 SV-GKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEEWT-VATTAKTCEG-T 2936

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L+   EYMFRV A N  G S+    + P+  K A   P+           + E++ I
Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKI 2996

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR------IQKLSINTTYQFRIY 1840
               P     G P  D K+E K++G+  K          +      I+  + +   ++ I 
Sbjct: 2997 D-IPVI---GCP--DPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTIT 3050

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N +GT+   T +  + I     PP+ P    + E +S  VTL W  PE  GG  I NY
Sbjct: 3051 ATNSVGTA---TEEITVIILDKPGPPTGPVK--IEEVSSNYVTLSWEPPEYTGGCQINNY 3105

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
            I+E +     +W +IV+   +     +  +K   E  FR+SAEN  G S    S +V  +
Sbjct: 3106 IVEKRDTTTTAW-QIVSATIARTTIKVTKLKTGIEYQFRVSAENRYGKSPAIVSPAVVAQ 3164

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
               T P  P  P  I     + +   W  P  +GG+P+LGY+I  ++    +W ++ K+ 
Sbjct: 3165 YPFTQPVAPGTPT-ISAATKDTMTVEWKAPTNNGGSPVLGYHIERKEKNSLLWTKLNKLL 3223

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            +    F   +L E   Y  R+YA N  GLSE  +  E
Sbjct: 3224 IPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISE 3260



 Score =  182 bits (442), Expect = 1e-43
 Identities = 161/683 (23%), Positives = 282/683 (41%), Gaps = 31/683 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKNITKTQ 1437
            P PP  P + +  S+++++ W  P   G + I  YVVE +E    EW+       +  T 
Sbjct: 3668 PGPPNNPKVTDHSSTTVSLSWSRPIYDGGANITGYVVEMKEAADDEWVICTPPTGVQATH 3727

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494
             +++ L+ N+ Y FR  AVN   + +  +      VI   K+++P +E      K +   
Sbjct: 3728 YTVRKLRENAEYSFRICAVNYEGLGEHVDLPG--SVIAAEKLEAPEIELDADLRKIVNVR 3785

Query: 1495 PNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
                + L     G P+P+V W + DG   + A+    +                   +  
Sbjct: 3786 ATATLRLFVTIRGKPEPEVKWSKADGTLNERAQIEVTSSYTMLVIDNVDRFDTGKYVVTL 3845

Query: 1554 NDHGEVETSCV-VGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             +    +T+ V V +   P    + E  D+KQ + V   W    +  G      I  K  
Sbjct: 3846 ENLSGSKTAFVNVRVLDSPSAPTNLEVKDVKQ-NSVSLCWEPPLIDGGAKISHYIVEKRE 3904

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKP 1669
             K         T   + S I I +L++     + + A N  G      T +V   +P  P
Sbjct: 3905 QKRMAFTSV-CTNCVRNSYI-ISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSEPPLP 3962

Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
             G V + +++R +VT+ W+ P +DGG ++T Y +E     +++W    +V + +E   + 
Sbjct: 3963 PGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCEV-KALEA-TVD 4020

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
             L+   EY FRVIA N  G S+A     P+V+K     P              + + I  
Sbjct: 4021 GLSTGEEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLLFDTYSVKAGDDLKID- 4079

Query: 1789 FPSEKNGGSPIIDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
             P  K    P + +K   ++ ++  +             I+  + + T ++ I   + +G
Sbjct: 4080 VPF-KGRPQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVG 4138

Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
            T         +     L  P  P N  V E ++  V+L W  P  +GG  I NY++E + 
Sbjct: 4139 TK------SAVIAVIILDKPGPPSNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRD 4192

Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
                +W +IV+   +     +  + +  E  FRI++EN  G S   +S  V  +     P
Sbjct: 4193 TTTTTW-QIVSATVARTSIKVTRLTQGTEYQFRIASENRYGKSSAIDSVPVVAQYPFEPP 4251

Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
             PPT  L +       ++  W  P  DGG+P+ GY+I  ++    +W +V +  +   +F
Sbjct: 4252 GPPT-NLHVAHASKYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWTKVNRGLLTENQF 4310

Query: 2027 NIRDLSENHTYMIRIYARNEIGL 2049
             +    E   Y  R+YA N  G+
Sbjct: 4311 KMTGTEEGLMYQFRVYAENIAGI 4333



 Score =  181 bits (441), Expect = 2e-43
 Identities = 203/908 (22%), Positives = 362/908 (39%), Gaps = 71/908 (7%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKK------KSVIEDTEKFTL 1244
            EEP    +  + + ++V   +   +TV    + +  VTW K       ++VI+ T+ FT 
Sbjct: 4846 EEPVFEISNEMRKTLIVKDGSSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTS 4905

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRG 1302
            IS        + +   +D  +YT  L +   TT L   V V++ P      E +   K  
Sbjct: 4906 IS--------LEQANREDSGKYTVTLSNVAGTTSLALNVRVLDSPGAPARVEVKDVTKSS 4957

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
            + VT          P   ++V+ +   K   T+  +      LT K     + G+Y  R+
Sbjct: 4958 ATVTWDTPENEGGGPVKNYLVDIREASKKGWTR--LTDTCHRLTYKVTNLQEGGVYYFRV 5015

Query: 1363 --ENNCGH---ADVEMNVTI------LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              EN  G    A+ +    I      ++KPSPP K  + ++   S+ + W +PE  G S 
Sbjct: 5016 TGENEYGTGLPAETKEGTKITGITKMIEKPSPPPKLGVTDVTKESVTLAWVKPEQDGGSR 5075

Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
            I  Y+VE  E    +W+          ++  L+ N+ Y FR  A N    S+  E     
Sbjct: 5076 ITGYLVEALEKGQEKWVKCGTTKFIHFTVSGLRENAEYFFRVRAENHAGFSETKEMVN-- 5133

Query: 1472 KVIKETKIQSPTVEK---PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKA 1527
             V+ + + + P +     P   +       ++      G P PKV+  +D  +LK T + 
Sbjct: 5134 AVVVKDQFECPEINMKNFPHNTVYVRAGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRF 5193

Query: 1528 TYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI--KQ 1582
              E   +                Y   A N  G  ++   + +  +P       ++    
Sbjct: 5194 NAEVTPDSIKIILRESVAGDSGRYDITASNSSGTSKSFLNIVVLDRPSAPQGPVELFDVT 5253

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            +  V  +WL  A   G P    I  K      N    ++++      ++I +L      +
Sbjct: 5254 EDSVSLKWLAPAYDGGSPITNYIIQKRETTTAN--WMDVSSAVARCTMKIMKLTTGLEYQ 5311

Query: 1643 YTIEASNTAGTS----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
            + I A N  G S    S  V++ + Y  P  P  P I   ++RE +T+ WK P  DGG  
Sbjct: 5312 FRIRAENKYGISEHIDSPPVSVNLPYTVPEAPSTPEI-TAVTRECITVAWKEPKSDGGSH 5370

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756
            +  Y ++  + ++  W +V         + I  +N    Y F+V A+N  G S  +  S+
Sbjct: 5371 VFGYHLQMKDKNSILWQRVNKTVIRATHFKITNINAGLIYEFKVAAENAAGVSVFSKVSD 5430

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKX 1815
             ++   A + P           I   +V ++W     +GGSPI  Y +E K+    +W  
Sbjct: 5431 AVLAIDACEPP----LNLRIIDITKNTVTLSWEKPNYDGGSPITGYIIEKKEGSSSRWFK 5486

Query: 1816 XXXXXXXXARIQKLSIN--TTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPR 1870
                     R     +N   TY+FR+ ARN +G+ S P       T   T   P    P+
Sbjct: 5487 ANLTNVTDTRFTVTGLNQDETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQ 5546

Query: 1871 NFV--VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
             ++  V       V LK+        +P   +  + K +K            S     + 
Sbjct: 5547 EYLSEVKFRAESDVELKFNIIAK--PAPTIEWFKDGKELKPSVQLSFKHTFESTSVF-LR 5603

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988
            +    +   + +  +N++G +  T    ++ +K    P PP   ++ + V ++ +   W 
Sbjct: 5604 DTTRLNSGSYEVKVKNSLGSACATVKLLIQ-DK----PGPPAGEIQFKKVTADNITIMWS 5658

Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             P  +GGA +  Y +  R+ ++ MW  V +  V+ +  N+  L + + Y+ R+   N+ G
Sbjct: 5659 PPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCI-VNVPRLIQGNEYIFRVRGVNKYG 5717

Query: 2049 LSEPLESD 2056
            + +PLES+
Sbjct: 5718 IGDPLESE 5725



 Score =  181 bits (440), Expect = 2e-43
 Identities = 208/901 (23%), Positives = 362/901 (40%), Gaps = 55/901 (6%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249
            +E P I     L + + V A     L V I  +   +V W K    + +  +  + S   
Sbjct: 3767 LEAPEIELDADLRKIVNVRATATLRLFVTIRGKPEPEVKWSKADGTLNERAQIEVTSSYT 3826

Query: 1250 KRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
               L+I      D  +Y   L  L    T  + V V++ P    + E +  +K+ S V+L
Sbjct: 3827 M--LVIDNVDRFDTGKYVVTLENLSGSKTAFVNVRVLDSPSAPTNLEVK-DVKQNS-VSL 3882

Query: 1308 LVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
              +            +IV  +  K+   T    +    S  I  ++      +++   N 
Sbjct: 3883 CWEPPLIDGGAKISHYIVEKREQKRMAFTSVCTNCVRNSYIISDLQQGGRYYFRVLAVNE 3942

Query: 1366 CG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
             G    A  +  V + + P PPGK ++L++   ++ + W++PEN G S I  Y+VE Q  
Sbjct: 3943 LGVGLPASTDQ-VKVSEPPLPPGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPK 4001

Query: 1423 DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
               +W     +   + ++  L T   Y FR  AVN+   SDA        V+K+  ++ P
Sbjct: 4002 GDDKWTLCCEVKALEATVDGLSTGEEYAFRVIAVNDKGKSDAKPLISPV-VVKDITVE-P 4059

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
             +       + +  +D+++   F G PQP+V+W +DG+ LK  + T  N           
Sbjct: 4060 IINLLFDTYSVKAGDDLKIDVPFKGRPQPEVSWKKDGQLLK--QTTRVN-----VLTSKS 4112

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKP----VITISNEDIKQKHKVGDEWLVTAVIEG 1598
                  K    +D G+ E +    +  K     VI +         KV +       +  
Sbjct: 4113 SSKIVIKDATKDDTGKYEITLTSSVGTKSAVIAVIILDKPGPPSNIKVDEVSADFVSLSW 4172

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAG 1652
             PP      +  N +   ++   TT +  S       I++  L +    ++ I + N  G
Sbjct: 4173 DPPTYDGGCQINNYVVEKRDTTTTTWQIVSATVARTSIKVTRLTQGTEYQFRIASENRYG 4232

Query: 1653 TSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
             SS ++    V   P +P GP   + +   S+  + + W  P  DGG  +T Y IE  E 
Sbjct: 4233 KSSAIDSVPVVAQYPFEPPGPPTNLHVAHASKYGMLVLWNRPASDGGSPVTGYHIECKEQ 4292

Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768
            ++  W KV         + +    E   Y FRV A+N  G     ++   V   A D P 
Sbjct: 4293 NSLLWTKVNRGLLTENQFKMTGTEEGLMYQFRVYAENIAGIGPCTKASDAV--AARD-PC 4349

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXXXXAR 1825
                      I   SV + W   E +GG  I  + VE K+   G+  K            
Sbjct: 4350 EPPRNLRVTNITRTSVSLFWDKPEYDGGVKITGFIVERKELPNGRWLKCNFTNLQDTYFD 4409

Query: 1826 IQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVT 1883
            +  L+ +  Y+F + A+N     S P  S   +T+   + PP+      + +    R+  
Sbjct: 4410 VTGLTEDVQYEFHVIAKNSAELLSAPSESTGPVTVKDDVDPPTIILEDKLRQLVVIRAGE 4469

Query: 1884 LKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            L   + E  G   P+ ++  + K ++ K+  +I +   +     + +   +D   + ++ 
Sbjct: 4470 LIRLDAEITGRPLPVVSWSKDGKEIEAKARCEITSTNFNT-TLIVRDAIRRDSGQYVLTL 4528

Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
             N  G    T S +V   K    P PP+ PL I  + +     +WG P+ +GGA ++ Y 
Sbjct: 4529 HNVAG----TRSVAVNC-KVLDRPGPPSGPLAITGLTAEKCSLAWGPPQENGGAEIMHYI 4583

Query: 2003 IAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            +  R+ ++  W  V G +   T K  +  L + + Y+ R+   N+ G  EPLES EP K 
Sbjct: 4584 VEKRETSRLAWTLVYGDMKATTCK--VTKLLKGNEYIFRVRGVNKYGDGEPLES-EPTKA 4640

Query: 2062 I 2062
            +
Sbjct: 4641 M 4641



 Score =  176 bits (428), Expect = 6e-42
 Identities = 136/537 (25%), Positives = 222/537 (41%), Gaps = 12/537 (2%)

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295
            I DT KFT+   ++K     R C  +         +  K   + K+E  +F     D  +
Sbjct: 987  ITDT-KFTVTKLLEKLEYQFRVCAINKVGVGEHADVPGKVLVEDKLEAPDFELD-ADMRK 1044

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
               I+  S + L V  +  P P  +W      IK+       +    ASL I+ V+  D+
Sbjct: 1045 MINIRAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQV--DVTGSYASLVIENVDRFDS 1102

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
            G Y L  EN  G     ++V +LD PSPP    + EI  +S+ + W+ P   G S I +Y
Sbjct: 1103 GKYTLTAENASGTKSAFISVRVLDSPSPPSNFTVKEITKNSVTLTWEPPLLDGGSKIRHY 1162

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            +VE +E     +  +    +    ++ L     + FR  A NE  +   ++  E  K+ +
Sbjct: 1163 IVEKRESTRKVYSPITTCNRMSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISE 1222

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
            + +         + N T     +  +      +   +V       +  T  AT +     
Sbjct: 1223 KPQPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVK-ALET 1281

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQKPVI--TISNEDIKQKHKVGDEWL 1591
                        +K  A ND G+ +   +    + +  VI   +  +      +VG +  
Sbjct: 1282 VIPNLLKGEEYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLK 1341

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +   I G P P + W K+G  L+     N+T     + + IK+  R     Y I  SN  
Sbjct: 1342 IEVPIAGHPKPTIAWTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNAL 1401

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G     + + + DKP  P GPV + EIS ES+T+ W+PP   GG  ++ Y +EK +    
Sbjct: 1402 GCKDATIEVIILDKPGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTT 1461

Query: 1712 RWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
             W+ V A V R   T  I  L    EY FR+ A+N  G S A+ S+P++ +     P
Sbjct: 1462 NWMVVSATVAR--TTLKIGNLKTGAEYQFRIFAENRYGKSYAIVSDPLLAQYPFQEP 1516



 Score =  175 bits (426), Expect = 1e-41
 Identities = 197/898 (21%), Positives = 362/898 (40%), Gaps = 90/898 (10%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249
            +EE  ++  +++       A  D  + + +      +VTW +    +    ++T+ S  +
Sbjct: 5934 LEEADLDLDVQMTTQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTER 5993

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVT 1306
              TL+I K T DD  +Y   LL+ ++    + ++V    K++D     ++  +K  S   
Sbjct: 5994 ATTLVIPKVTRDDCGKY---LLEIENGVG-EPKIVTVSLKVLDSPSACQKLLVKNVSRGE 6049

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAGI---YKLR 1361
            L + ++A P  +    V + I++K   T  +    +A    T  KV   D  +   +++ 
Sbjct: 6050 LTLSWEA-PVIDGGCPVTNYIVEKKGSTMKAYQVITAECANTSYKVSGLDIDVAYFFRVS 6108

Query: 1362 LENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             EN  G  D       V   + P P     +L+    S+ + W  P++ G S I  Y++E
Sbjct: 6109 AENEYGVGDPCETSGPVRATETPGPVKDLVMLDSTKGSVTLQWTRPDHDGGSHITDYIIE 6168

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE----TTEYYKVI 1474
             +  +   W       +    +  LK N+  +FR +A NE   SD S+    T + + + 
Sbjct: 6169 KKAQEENSWTLAATCKRCSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIP 6228

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYE 1530
             E  +     + P   +     ++I +   F G P+P ++W +D   LK ++     T +
Sbjct: 6229 PEANLS----DYPNAELAVRVGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTD 6284

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFN----DHGEVETSCVVGIQQKPVITISNEDIKQKHKV 1586
            N+               Y  +  N    ++ ++     +G    PV  I  ++IK +  +
Sbjct: 6285 NKTAVTVRGAKKEHAGQYTLVLDNRTIKNYFDINV-ITLGPPSVPVGPIRFDEIKAQSII 6343

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTI 1645
               W       G    E+  Y    +  +   + +       +  +I  L +    ++ +
Sbjct: 6344 -ISWDEPKEDGG---GEITCYSVEKRETSQANWKMVCSSVVRTTFKIPNLVKGTQYQFRV 6399

Query: 1646 EASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
             A N  G S    S++V  +   KP  P G  +   ++ + +TI W+ P  DGG  +  Y
Sbjct: 6400 RAENKYGVSNPLTSLDVVAQHQYKPPGPPGKPVAYNVTSDGMTIRWEAPDFDGGSPIMGY 6459

Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
             +EK + ++  W KV         Y I  L E  EY FRV A+N  G S   E      K
Sbjct: 6460 HVEKKDRNSLMWQKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLSPVSEQS----K 6515

Query: 1762 TALDV-PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX 1820
             AL + P           +  +SV + W   +K+GGS I+ Y VE +Q   KW       
Sbjct: 6516 HALAISPVDPPGTPVCIDVTRDSVTLQWDTPKKDGGSKIVGYSVERRQGRGKWLRCNFTD 6575

Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                +  +  LS    ++FR+ ARN +GT               ++PPS    +++++  
Sbjct: 6576 VSETQFTVTALSPGDRFEFRVIARNAVGT---------------ISPPSNSSGYIMTKDE 6620

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
            S S  ++W+ P+          +    ++ G+   ++V           ++ KE D+ I 
Sbjct: 6621 SISPEIEWS-PDQQLTLRAGENVRLSCSITGRPVPQVV---------WYKDGKEIDKRIM 6670

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
             I  E + G+   T             P P   P+    + +      W  PE DG + +
Sbjct: 6671 -IDIEISTGIGTNT-------------PGPVEGPIRFTGITAEKCTVWWNPPENDGCSAI 6716

Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
              Y +  R+ ++  W  V         +N  +L + + Y  RI A N+ G+ +PL+SD
Sbjct: 6717 THYVVEKRETSRISWALVTS-KCEACSYNATNLIKGNEYQFRISAVNKFGVGKPLDSD 6773



 Score =  174 bits (423), Expect = 3e-41
 Identities = 129/465 (27%), Positives = 208/465 (44%), Gaps = 23/465 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G P PE+ W K   +++   + ++T    + VI  + + R  S KYT+ A N +GT S
Sbjct: 1060 VRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVI--ENVDRFDSGKYTLTAENASGTKS 1117

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
              ++++V D PS P    + +EI++ SVT+ W+PPL DGG ++  Y +EK E     +  
Sbjct: 1118 AFISVRVLDSPSPPSNFTV-KEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSP 1176

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXX 1774
            +   +R   ++ ++ L E   + FRV+A+N  G    A  +EPI I      P       
Sbjct: 1177 ITTCNR--MSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEKPQPPGKVTVVD 1234

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINT 1833
                + N +V + W     +GGS I  Y+VE+  ++ + W            I  L    
Sbjct: 1235 ----VSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVKALETVIPNLLKGE 1290

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
             YQF++ A N+ G S P      +     +  P+  R  V + S      LK   P +  
Sbjct: 1291 EYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAV-RPKVSTYSVQVGYDLKIEVPIAGH 1349

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLP 1951
              P   +  +   +K    T  V V  S H+    I++    D  ++ I+  N +G    
Sbjct: 1350 PKPTIAWTKDGIALKQ---TTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNALGCKDA 1406

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
            T  + + L+K    P PPT P+++  + +  +  SW  P + GG P+  Y +  RD T T
Sbjct: 1407 T-IEVIILDK----PGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTT 1461

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
             WM V      T    I +L     Y  RI+A N  G S  + SD
Sbjct: 1462 NWMVVSATVART-TLKIGNLKTGAEYQFRIFAENRYGKSYAIVSD 1505



 Score =  171 bits (417), Expect = 1e-40
 Identities = 117/371 (31%), Positives = 169/371 (45%), Gaps = 14/371 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+ + + A I G P P V W K G ++       I   +  + I +KE  R    +Y + 
Sbjct: 650  GETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTDFVARIIVKEAIRVDGGQYILL 709

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW--KPPLDDGGLELTKYAIE 1704
              N  G  SV + +KV D+P  PEGP+ +  +S E  +I W  KPP+ DGG +++ Y +E
Sbjct: 710  VKNVGGEKSVTINVKVLDRPGPPEGPIAIYGVSNEKCSISWKPKPPVQDGGSDVSHYIVE 769

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            + E     W  V +         I KL    EY+FRVI  N  G  E LESEP++ +   
Sbjct: 770  RRETSRLVW-TVVEPKVQTLNLKITKLLPGNEYIFRVIPVNKYGVGEPLESEPMIARNPF 828

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXX 1823
              P+          I  +S+ +TW     +GGSPI  Y VE + ++G +W          
Sbjct: 829  VTPN-PPTDVEVSTITKDSMVVTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSE 887

Query: 1824 ARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP--PSQPRNFVVSESTS 1879
             R +   +  N +Y+FR+ A N  G   P          K L P   + P N   +  TS
Sbjct: 888  LRFRVTGLLENHSYEFRVAAENAAGVGTP---SQPTVYYKALDPVFKAGPPNNPKALDTS 944

Query: 1880 RS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHEHCIENIKEKDEII 1937
            RS VTL W +P  +GG  I  YI+E        W T     G +  +  +  + EK E  
Sbjct: 945  RSTVTLIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQ 1004

Query: 1938 FRISAENTVGV 1948
            FR+ A N VGV
Sbjct: 1005 FRVCAINKVGV 1015



 Score =  169 bits (412), Expect = 5e-40
 Identities = 169/688 (24%), Positives = 282/688 (40%), Gaps = 45/688 (6%)

Query: 1204 EFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
            E + + A +D  L   +   P+ T  V W K   ++E  EK++L     +   +I+ C  
Sbjct: 7613 ETVTISAGSDLVLDGAVGGKPEPT--VYWSKGDKILELGEKYSLTYTATRAMAVIKNCDR 7670

Query: 1261 DDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQP 1317
             D   Y   + +A    T  + ++V++ P    D     R+ +    V+  +  +     
Sbjct: 7671 SDTGRYCLTVKNASGVKTAWVNLKVLDTPGPPADKIVISRVTEEKCTVSWKIPLEDGGDS 7730

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVT 1376
               ++V  +   +        + K+ S    ++   +  I+++R  N  G    +E    
Sbjct: 7731 VTHYVVERRETSRLNWVLVEAECKTLSCVSSRLIKNNEYIFRVRGVNKFGPGVPLESEPV 7790

Query: 1377 ILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
            I       PS PG P    +    + I W +PE+ G S I  Y+V+ +E  +T W  V  
Sbjct: 7791 IARNAYTIPSQPGTPETTAVGKEHVIIEWLKPESDGGSEISNYIVDKREKSSTRWTRVNK 7850

Query: 1433 ---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP------- 1482
               I  T+  +  L   S Y+FR  AVN    S  S+ T Y      T   +P       
Sbjct: 7851 TYTIYDTRLKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRIT 7910

Query: 1483 -TVEKPLKNITTEPNED--IELT-CIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXX 1537
             T +  +    T P  D   +++  +   + +    WYR   K LKT +           
Sbjct: 7911 DTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKK 7970

Query: 1538 XXXXXXXXXXYKCIAFND-HGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTA 1594
                           F+D   EVE    +   + P + ++ +D+K+    + G    +  
Sbjct: 7971 YRFRVAALNSKGTGEFSDPSSEVEP---LERTEMPDLELA-DDLKKTVCLRAGGTLRLMV 8026

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             + G P P V W K G +L++ + Y I T +  + + ++++ R  S KY +EA N +G  
Sbjct: 8027 FVTGRPTPVVAWRKTGVELQS-RGY-IETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKK 8084

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            +  + +KVYD P  P G V +++ +RESV I W  P  DGG  ++ Y IEK E  N +  
Sbjct: 8085 TATILVKVYDTPGPP-GSVKVKDYTRESVVITWDVPSVDGGAHVSNYIIEKREA-NMKSY 8142

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            K    +     + I  L E   Y FRV+ +N  G  E  E+   V+    +VPS      
Sbjct: 8143 KTVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVL--VCEVPSVPLDLQ 8200

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSI 1831
                +   SV + W     +GGS +  Y +E  + G  +W          ++  I  L  
Sbjct: 8201 IID-VTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPSLME 8259

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITI 1859
            N  Y FR+ A N  G S P  +   +TI
Sbjct: 8260 NDQYLFRVRATNSRGASEPMDTVTPVTI 8287



 Score =  151 bits (365), Expect = 3e-34
 Identities = 121/501 (24%), Positives = 211/501 (42%), Gaps = 24/501 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P PEV W K    L    +  +T+    +++ I  + R  + KY +   N +G+ +
Sbjct: 3796 IRGKPEPEVKWSKADGTLNERAQIEVTSSY--TMLVIDNVDRFDTGKYVVTLENLSGSKT 3853

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
              V ++V D PS P   + ++++ + SV++ W+PPL DGG +++ Y +EK E     +  
Sbjct: 3854 AFVNVRVLDSPSAPTN-LEVKDVKQNSVSLCWEPPLIDGGAKISHYIVEKREQKRMAFTS 3912

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
            V   +    +Y I  L +   Y FRV+A N +G      ++ + +      P        
Sbjct: 3913 VC-TNCVRNSYIISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSE----PPLPPGKVS 3967

Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTT 1834
               +   +V ++W   E +GGS I +Y VE++ +G  KW          A +  LS    
Sbjct: 3968 LLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCEVKALEATVDGLSTGEE 4027

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y FR+ A N+ G S        + + K +T          + S      LK   P     
Sbjct: 4028 YAFRVIAVNDKGKSDAKPLISPVVV-KDITVEPIINLLFDTYSVKAGDDLKIDVPFKGRP 4086

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
             P  ++  + + +K  +   ++T   S  +  I++  + D   + I+  ++VG      +
Sbjct: 4087 QPEVSWKKDGQLLKQTTRVNVLT-SKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIA 4145

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
              + L+K    P PP + +++  V ++ V  SW  P +DGG  +  Y +  RD T T W 
Sbjct: 4146 VII-LDK----PGPP-SNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRDTTTTTWQ 4199

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074
             V      T    +  L++   Y  RI + N  G S  ++S      +P    +  E PG
Sbjct: 4200 IVSATVART-SIKVTRLTQGTEYQFRIASENRYGKSSAIDS------VPVVAQYPFEPPG 4252

Query: 2075 EQTEVXXXXXXXXXXXXXWLR 2095
              T +             W R
Sbjct: 4253 PPTNLHVAHASKYGMLVLWNR 4273



 Score =  144 bits (348), Expect = 3e-32
 Identities = 171/793 (21%), Positives = 304/793 (38%), Gaps = 62/793 (7%)

Query: 1349 KVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            K+ N +AG+   +K+  EN  G    + V   V  +D   PP    I++I  +++ + W+
Sbjct: 5400 KITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEPPLNLRIIDITKNTVTLSWE 5459

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            +P   G S I  Y++E +E  ++ W   ++ N+T T+ ++  L  + +Y FR  A N V 
Sbjct: 5460 KPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQDETYEFRVMARNAVG 5519

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
                           +T   +P +E P   L  +      D+EL       P P + W++
Sbjct: 5520 SLSNPSMIAGPATCVDT-YGAPEIEIPQEYLSEVKFRAESDVELKFNIIAKPAPTIEWFK 5578

Query: 1518 DGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
            DGK+LK +     K T+E+                Y+    N  G    +  + IQ KP 
Sbjct: 5579 DGKELKPSVQLSFKHTFES-TSVFLRDTTRLNSGSYEVKVKNSLGSACATVKLLIQDKPG 5637

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT--SVI 1630
                  +I+ K    D   +           ++ +    K E  +       EK    ++
Sbjct: 5638 PPAG--EIQFKKVTADNITIMWSPPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCIV 5695

Query: 1631 RIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
             +  L + +   + +   N  G      S   +    +  PS+P  P +   I++ ++T+
Sbjct: 5696 NVPRLIQGNEYIFRVRGVNKYGIGDPLESEPVIAKNAFVPPSEPSKPKVTM-ITKSTMTV 5754

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQ 1744
             W+ P  DGG ++  Y +EK E  + +W KV     RD     +  L EN EY FRV A 
Sbjct: 5755 IWERPALDGGSDIDGYYLEKREKKSLQWFKVVKGTIRDTRQK-VSNLVENNEYQFRVCAV 5813

Query: 1745 NPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N  G     E+  +      +D+P             + S+ + W     +GGS I  Y 
Sbjct: 5814 NKAGAGNYSEASDLYRAYDPIDLPGEPSKLRVVDSTKS-SITLGWEKPIYDGGSEITHYV 5872

Query: 1804 VE-IKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            ++ +  E ++W            +   L   T Y F++ A N  G       D K     
Sbjct: 5873 LDQMNTEEREWVTINPQVKACEYVVSHLKPGTYYFFKVSAVNCKGKG----EDIK----- 5923

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI-IEFKTVKGKSWTKIVTVGG 1920
             +  P Q ++ +        V +  T+  +  G  +  +I ++ +     +W +      
Sbjct: 5924 -MYQPVQAKDILEEADLDLDVQMT-TQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMA 5981

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP----SPPTA--PLE 1974
            + + + I + +    ++      +  G  L      V   K  TV       P+A   L 
Sbjct: 5982 ADNRYTISSTERATTLVIPKVTRDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLL 6041

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
            ++ V    +  SW  P  DGG P+  Y +  +  T   +  +     NT  + +  L  +
Sbjct: 6042 VKNVSRGELTLSWEAPVIDGGCPVTNYIVEKKGSTMKAYQVITAECANT-SYKVSGLDID 6100

Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWL 2094
              Y  R+ A NE G+ +P E+  P +        A E PG   ++             W 
Sbjct: 6101 VAYFFRVSAENEYGVGDPCETSGPVR--------ATETPGPVKDLVMLDSTKGSVTLQWT 6152

Query: 2095 R-EHNMDADIRSY 2106
            R +H+  + I  Y
Sbjct: 6153 RPDHDGGSHITDY 6165



 Score =  141 bits (342), Expect = 2e-31
 Identities = 113/422 (26%), Positives = 183/422 (43%), Gaps = 28/422 (6%)

Query: 1642 KYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695
            +Y + A N  G       S + V     D P +PE  ++    +R SV + W PP  DGG
Sbjct: 2168 EYRVYAENIVGIGKCSKVSEICVAQDPCDPPGRPEALIV----TRHSVKLRWTPPQYDGG 2223

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALE 1754
              +T Y +EK +    +W+K +  +     + +  L E+ +Y FR+IA+N  G  S+  E
Sbjct: 2224 SLITGYVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSE 2283

Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID---YKVEIKQEG 1810
            S   I  K  +D P           +  ++   T+       G PI     +K +++ E 
Sbjct: 2284 STGSITAKDEVDPPKYETDPMYNQMLVVKAGE-TFNLEATVEGKPIPTAQWFKGDVEVEN 2342

Query: 1811 KKWKXXXXXXXXXARIQKLSINTTY-QFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQ 1868
                           + K ++     Q+ +   N  GT S+P++        K L  P  
Sbjct: 2343 SARAEIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSV-------KVLDRPGP 2395

Query: 1869 PRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
                  VS  T    +L W  P  +GG+ +++YII+ +     +WT + +  G+      
Sbjct: 2396 SEGPLTVSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVT 2455

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
            + +K  +E IFR+ A N  GV  P ES  V +      P PP   LEI  +  + +   W
Sbjct: 2456 KLLKG-NEYIFRVMAVNKYGVGEPLESVPVIMRNPFVPPGPPQE-LEITNITRDSMTVCW 2513

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              PE +GG+ ++GY I  RD     W +  K  V  L+F +  L+E+H Y  R+ A N  
Sbjct: 2514 NRPETNGGSTIVGYIIEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVA 2573

Query: 2048 GL 2049
            G+
Sbjct: 2574 GV 2575



 Score =  138 bits (335), Expect = 1e-30
 Identities = 171/736 (23%), Positives = 288/736 (39%), Gaps = 64/736 (8%)

Query: 1358 YKLRLEN--NCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            Y++  EN    G       + +   P  PPG+P  L +   S+ + W  P+  G S I  
Sbjct: 2169 YRVYAENIVGIGKCSKVSEICVAQDPCDPPGRPEALIVTRHSVKLRWTPPQYDGGSLITG 2228

Query: 1415 YVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471
            YVVE +++   +W+  S  NIT+ + ++  L  +S Y FR  A N    IS  SE+T   
Sbjct: 2229 YVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTG-- 2286

Query: 1472 KVIKETKIQSPTVE-KPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKA 1527
             +  + ++  P  E  P+ N  +  +  E   L     G P P   W++ D +   +A+A
Sbjct: 2287 SITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARA 2346

Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-----VITISNED 1579
              +N   +               Y  +  N  G       V +  +P      +T+SN  
Sbjct: 2347 EIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSN-- 2404

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRS 1638
               + K    WL      G      I  K   +  +   + + + +   ++ ++ +L + 
Sbjct: 2405 -VTEEKCSLSWLPPRHDGGAGVSHYIIQK---RETSRLTWTVVSSDCGATMFKVTKLLKG 2460

Query: 1639 HSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEWKPPLDDG 1694
            +   + + A N  G    +E    +   P  P GP   + +  I+R+S+T+ W  P  +G
Sbjct: 2461 NEYIFRVMAVNKYGVGEPLESVPVIMRNPFVPPGPPQELEITNITRDSMTVCWNRPETNG 2520

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
            G  +  Y IEK +    RW K          + +  L E+ EY FRV A+N  G      
Sbjct: 2521 GSTIVGYIIEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXX 2580

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813
                  K      +             +S+ ++W     +GG  I  Y VEI K + ++W
Sbjct: 2581 P---TFKPGCPTNAHVVDTR------KDSISLSWHRPIYDGGCEIQGYAVEITKADEEEW 2631

Query: 1814 KXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLP------YTSDDKITIGKTLT 1864
                      A    I KL  +  Y+ RI A N++G   P          DKI   + + 
Sbjct: 2632 VICTPPTGVNATKFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVIL 2691

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
                 +  VV    S  + +    P     +P   +  E   + GK     V  G    +
Sbjct: 2692 DSDLRKGIVVRAGGSMRICI----PFKGRPTPEIRWAKEDAELPGKVQ---VETGEDYSQ 2744

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
              I+   + D   + ++ EN+ G    T+S  V + K    P  P   L ++ +    V 
Sbjct: 2745 LSIDICDKYDAGKYILTLENSAG----TKSAFVSV-KVLDTPGAP-VNLTVKDIKRESVT 2798

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
             +W  P  DGGA +  Y +  R+ T+ ++  V      T  + + DL E   Y  R+ A 
Sbjct: 2799 LTWEPPLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKT-SYRVTDLKEGTLYYFRVLAE 2857

Query: 2045 NEIGLSEPLESDEPFK 2060
            NE G+ E  E+++  K
Sbjct: 2858 NEFGVGEAAETEDSVK 2873



 Score =  137 bits (332), Expect = 3e-30
 Identities = 97/343 (28%), Positives = 158/343 (46%), Gaps = 18/343 (5%)

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            + + A N  G S++  +  IV+   LD PS          +  +SV + W     +GGSP
Sbjct: 5217 YDITASNSSGTSKSFLN--IVV---LDRPSAPQGPVELFDVTEDSVSLKWLAPAYDGGSP 5271

Query: 1799 IIDYKVEIKQEGK-KWKXXXXXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
            I +Y ++ ++     W            +I KL+    YQFRI A N+ G S  +     
Sbjct: 5272 ITNYIIQKRETTTANWMDVSSAVARCTMKIMKLTTGLEYQFRIRAENKYGIS-EHIDSPP 5330

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI- 1915
            +++    T P  P    ++  T   +T+ W EP+S+GGS +  Y ++ K      W ++ 
Sbjct: 5331 VSVNLPYTVPEAPSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVN 5390

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
             TV  + H   I NI       F+++AEN  GVS+ ++     L   A  P     PL +
Sbjct: 5391 KTVIRATHFK-ITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEP-----PLNL 5444

Query: 1976 RMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033
            R++    N V  SW  P +DGG+P+ GY I  ++ + + W +    +V   +F +  L++
Sbjct: 5445 RIIDITKNTVTLSWEKPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQ 5504

Query: 2034 NHTYMIRIYARNEIG-LSEPLESDEPFKVIPGEGSHADEEPGE 2075
            + TY  R+ ARN +G LS P     P   +   G+   E P E
Sbjct: 5505 DETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQE 5547



 Score =  135 bits (326), Expect = 1e-29
 Identities = 112/432 (25%), Positives = 184/432 (42%), Gaps = 25/432 (5%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYD---KPSKPEGPVIMREISRESVT 1684
            R+  L  +HS ++ + A N AG    S   V  K  D   K   P  P  + + SR +VT
Sbjct: 891  RVTGLLENHSYEFRVAAENAAGVGTPSQPTVYYKALDPVFKAGPPNNPKAL-DTSRSTVT 949

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIA 1743
            + W  P+ DGG E+  Y +E     ++ W          +T + + KL E  EY FRV A
Sbjct: 950  LIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQFRVCA 1009

Query: 1744 QNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIID 1801
             N VG  E  +    ++++  L+ P           I+  +   +  F   +   +P I 
Sbjct: 1010 INKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIK 1069

Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            +     +  +  +           I+ +    + ++ + A N  GT   + S       +
Sbjct: 1070 WGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLTAENASGTKSAFISV------R 1123

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
             L  PS P NF V E T  SVTL W  P  +GGS I +YI+E +    K ++ I T    
Sbjct: 1124 VLDSPSPPSNFTVKEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSPITTCNRM 1183

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGS 1980
              +  +E + E     FR+ AEN  GV LP + ++ +++ +    P PP   + +  V +
Sbjct: 1184 SWK--VEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEK---PQPP-GKVTVVDVSN 1237

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
              V  +W  P  DGG+ +  Y + +       W       V  L+  I +L +   Y  +
Sbjct: 1238 TTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVC--ATVKALETVIPNLLKGEEYQFK 1295

Query: 2041 IYARNEIGLSEP 2052
            + A N+ G S+P
Sbjct: 1296 VSAINDKGKSDP 1307



 Score =  133 bits (321), Expect = 6e-29
 Identities = 104/431 (24%), Positives = 185/431 (42%), Gaps = 25/431 (5%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDK---PSKPEGPVIMREISRESVT 1684
            R+  L   HS ++ + A N AG    S+    +KV D    P  P  P +  + S  +V+
Sbjct: 3627 RVTGLTEGHSYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNPKVT-DHSSTTVS 3685

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVI 1742
            + W  P+ DGG  +T Y +E  E  ++ W+ +      V+   Y ++KL EN EY FR+ 
Sbjct: 3686 LSWSRPIYDGGANITGYVVEMKEAADDEWV-ICTPPTGVQATHYTVRKLRENAEYSFRIC 3744

Query: 1743 AQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPII 1800
            A N  G  E ++    VI    L+ P           ++   +  +  F + +    P +
Sbjct: 3745 AVNYEGLGEHVDLPGSVIAAEKLEAPEIELDADLRKIVNVRATATLRLFVTIRGKPEPEV 3804

Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             +        ++ +           I  +    T ++ +   N  G+   + +       
Sbjct: 3805 KWSKADGTLNERAQIEVTSSYTMLVIDNVDRFDTGKYVVTLENLSGSKTAFVN------V 3858

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
            + L  PS P N  V +    SV+L W  P  +GG+ I++YI+E +  K  ++T + T   
Sbjct: 3859 RVLDSPSAPTNLEVKDVKQNSVSLCWEPPLIDGGAKISHYIVEKREQKRMAFTSVCT-NC 3917

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
              + + I ++++     FR+ A N +GV LP  +  V++ +    P  P   + +  V  
Sbjct: 3918 VRNSYIISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSE----PPLPPGKVSLLDVTR 3973

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + V  SW  PE DGG+ +  Y + ++      W      +V  L+  +  LS    Y  R
Sbjct: 3974 HTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLC--CEVKALEATVDGLSTGEEYAFR 4031

Query: 2041 IYARNEIGLSE 2051
            + A N+ G S+
Sbjct: 4032 VIAVNDKGKSD 4042



 Score =  132 bits (319), Expect = 1e-28
 Identities = 146/610 (23%), Positives = 247/610 (40%), Gaps = 35/610 (5%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436
            K  PP  P  L+   S++ + W +P   G   I  Y+VE     + EW +      IT T
Sbjct: 931  KAGPPNNPKALDTSRSTVTLIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDT 990

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493
            + ++  L     Y+FR  A+N+V + + ++     KV+ E K+++P  E      K I  
Sbjct: 991  KFTVTKLLEKLEYQFRVCAINKVGVGEHADVPG--KVLVEDKLEAPDFELDADMRKMINI 1048

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCI 1551
                 + L     G P P++ W + DG+  +TA+     +                Y   
Sbjct: 1049 RAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLT 1108

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            A N  G       V +   P    SN  +K+  K+ V   W    +++G    ++  Y  
Sbjct: 1109 AENASGTKSAFISVRVLDSP-SPPSNFTVKEITKNSVTLTW-EPPLLDG--GSKIRHYIV 1164

Query: 1610 GNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDK 1665
              +    K Y+ ITT  + S  +++ L       + + A N  G    + +   +K+ +K
Sbjct: 1165 EKRESTRKVYSPITTCNRMS-WKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEK 1223

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P +P G V + ++S  +V++ W+ P+ DGG  ++ Y +E    D+  W   A V + +ET
Sbjct: 1224 P-QPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATV-KALET 1281

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              I  L +  EY F+V A N  G S+  +    V+   L +            +      
Sbjct: 1282 -VIPNLLKGEEYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDL 1340

Query: 1786 ITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
                P   +    I   K  + +KQ   +             I+  + +    + I   N
Sbjct: 1341 KIEVPIAGHPKPTIAWTKDGIALKQT-TRVNVTDSTHQTTLTIKDATRDDGGMYNINISN 1399

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
             +G      +  ++ I     PP+ P    V E ++ S+TL W  P   GG PI+NY++E
Sbjct: 1400 ALGCK---DATIEVIILDKPGPPTGP--VKVDEISAESITLSWEPPSYTGGCPISNYVVE 1454

Query: 1904 FKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
             +     +W  +  TV  +  +  I N+K   E  FRI AEN  G S    S  +  +  
Sbjct: 1455 KRDTTTTNWMVVSATVARTTLK--IGNLKTGAEYQFRIFAENRYGKSYAIVSDPLLAQYP 1512

Query: 1963 ATVPSPPTAP 1972
               P PP  P
Sbjct: 1513 FQEPGPPGTP 1522



 Score =  132 bits (319), Expect = 1e-28
 Identities = 86/298 (28%), Positives = 139/298 (46%), Gaps = 7/298 (2%)

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-X 1821
            LD P           +  E   + W P ++NGG+ I+ Y VE ++  +  W         
Sbjct: 4544 LDRPGPPSGPLAITGLTAEKCSLAWGPPQENGGAEIMHYIVEKRETSRLAWTLVYGDMKA 4603

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
               ++ KL     Y FR+   N+ G   P  S+    +    T P+ P N  V+  TS +
Sbjct: 4604 TTCKVTKLLKGNEYIFRVRGVNKYGDGEPLESEPTKAMDP-FTVPTPPTNVQVTAVTSEA 4662

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
            +T+ W  P S+GGS I+ Y+IE +   G  W ++             N++E  E  +R+ 
Sbjct: 4663 MTICWERPVSDGGSSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRVF 4722

Query: 1942 AENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
            AEN+ G+S P+     ++ E    +PSPP  P  +    + + + SW  P +DGGAP+ G
Sbjct: 4723 AENSAGLSAPSIPCPLIKAEDPQFLPSPPAKPKIVDSTKTTVTL-SWNKPLFDGGAPVTG 4781

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL-ESDE 2057
            Y +  R      W+   +   NT +F +  L+    Y+  I + N+IG+SEP  ESD+
Sbjct: 4782 YRVEYRKTLDDEWVVAVQNTKNT-EFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDK 4838



 Score =  130 bits (313), Expect = 5e-28
 Identities = 95/319 (29%), Positives = 136/319 (42%), Gaps = 9/319 (2%)

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815
            P+ +K  LD P           +  E  Y+ W     +GG+ I  Y +E ++  +  W  
Sbjct: 3458 PVTVKV-LDRPGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISHYIIEKRETSRLSWTM 3516

Query: 1816 XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV 1874
                    + +I KL     Y FR+ A N+ G   P  S+  I      T PS P     
Sbjct: 3517 VEPKIQAISYKITKLLPGNEYIFRVTAVNKYGVGEPLESEPVIA-RNPFTTPSAPSTPEA 3575

Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
            S  T  S+ L W  PESNGG+ I  YI+E +   G  WTK      +     +  + E  
Sbjct: 3576 SAITRDSIVLTWERPESNGGADIEGYILEKRDKDGVRWTKCNKKRLNDLRFRVTGLTEGH 3635

Query: 1935 EIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
               F++SAEN  GV  P+  S+ +++      P PP  P ++    S  V  SW  P +D
Sbjct: 3636 SYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNP-KVTDHSSTTVSLSWSRPIYD 3694

Query: 1994 GGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            GGA + GY + +++     W+       V    + +R L EN  Y  RI A N  GL E 
Sbjct: 3695 GGANITGYVVEMKEAADDEWVICTPPTGVQATHYTVRKLRENAEYSFRICAVNYEGLGEH 3754

Query: 2053 LESDEPFKVIPGEGSHADE 2071
            +  D P  VI  E   A E
Sbjct: 3755 V--DLPGSVIAAEKLEAPE 3771



 Score =  124 bits (300), Expect = 2e-26
 Identities = 103/398 (25%), Positives = 173/398 (43%), Gaps = 15/398 (3%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438
            P+PP  P I +    SI++ W  P   G S +  YVVE  E  + +W   + K +   + 
Sbjct: 7901 PAPPSVPRITDTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEF 7960

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497
                L  N  YRFR  A+N     + S+ +   + ++ T++    +   LK  +      
Sbjct: 7961 VAAGLAANKKYRFRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGG 8020

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
             + L     G P P V W + G +L++     T ++                Y   A N 
Sbjct: 8021 TLRLMVFVTGRPTPVVAWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENP 8080

Query: 1556 HGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
             G+   + +V +   P    ++  +D  ++  V   W V +V  G      I  K    +
Sbjct: 8081 SGKKTATILVKVYDTPGPPGSVKVKDYTRESVV-ITWDVPSVDGGAHVSNYIIEKREANM 8139

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVT--LKVYDKPSKPE 1670
            ++ K   +TT+ + ++ RI  L+      + +   N  G     E T  + V + PS P 
Sbjct: 8140 KSYK--TVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLVCEVPSVPL 8197

Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730
               I+ ++++ SVT+ W+ PL DGG  LT Y IE  +  ++RW  VA     V  + I  
Sbjct: 8198 DLQII-DVTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPS 8256

Query: 1731 LNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVP 1767
            L EN +Y+FRV A N  G SE +++  P+ I+    +P
Sbjct: 8257 LMENDQYLFRVRATNSRGASEPMDTVTPVTIQDIKVIP 8294



 Score =  122 bits (293), Expect = 1e-25
 Identities = 87/289 (30%), Positives = 123/289 (42%), Gaps = 8/289 (2%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQ 1836
            I  E   + W P E +G S I  Y VE ++  +  W          +     L     YQ
Sbjct: 6696 ITAEKCTVWWNPPENDGCSAITHYVVEKRETSRISWALVTSKCEACSYNATNLIKGNEYQ 6755

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            FRI A N+ G   P  SD  I      T P  P     +  T  S+T+ WT P S+GG+ 
Sbjct: 6756 FRISAVNKFGVGKPLDSDPVIA-QMQYTVPDAPGTPDATHVTGNSITMCWTRPRSDGGNE 6814

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            I  YI+E +  K   W K+ +        H + N+ E +E  FR+ AEN  GV  P  S 
Sbjct: 6815 IKQYILERREKKSLRWVKVSSKRAITELRHRVTNLTEGNEYEFRVMAENGAGVG-PASST 6873

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
            S RL K     S P+AP  I+++ S  + V   W  P +DGG  ++GYNI +   +   W
Sbjct: 6874 S-RLFKCREPTSAPSAPTVIKVIDSTKSSVTIEWTKPVFDGGMEIIGYNIDMCKASLEEW 6932

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062
              V        ++  + L     Y  R+ A N  G  E      P + +
Sbjct: 6933 HRVNSQICIHTRYTAKGLVPGELYKFRVSAVNGSGEGEASVMPNPVQAL 6981



 Score =  121 bits (291), Expect = 3e-25
 Identities = 107/441 (24%), Positives = 180/441 (40%), Gaps = 21/441 (4%)

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVY--DKPSKPEGPVIMR--EISRESVT 1684
            +++  L      ++ + A N AG S   + T  +   D    P  P + R  + ++ S++
Sbjct: 7859 LKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRITDTTKHSIS 7918

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            + W  P+ DGG +++ Y +E  E  + +W +          +    L  N +Y FRV A 
Sbjct: 7919 MTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKKYRFRVAAL 7978

Query: 1745 NPVGFSE----ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            N  G  E    + E EP+      D+                ++ +  F + +   +P++
Sbjct: 7979 NSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP--TPVV 8036

Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             ++    +   +             ++K+S   + ++ + A N  G            + 
Sbjct: 8037 AWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKKTA------TILV 8090

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
            K    P  P +  V + T  SV + W  P  +GG+ ++NYIIE +    KS+ K VT   
Sbjct: 8091 KVYDTPGPPGSVKVKDYTRESVVITWDVPSVDGGAHVSNYIIEKREANMKSY-KTVTTEC 8149

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
                  I  ++E     FR+  EN  GV  P E+    L     VPS P   L+I  V  
Sbjct: 8150 RKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLV--CEVPSVPL-DLQIIDVTK 8206

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + V   W  P  DGG+ L GY I    +    W  V     +  +F I  L EN  Y+ R
Sbjct: 8207 SSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPSLMENDQYLFR 8266

Query: 2041 IYARNEIGLSEPLESDEPFKV 2061
            + A N  G SEP+++  P  +
Sbjct: 8267 VRATNSRGASEPMDTVTPVTI 8287



 Score =  119 bits (286), Expect = 1e-24
 Identities = 161/786 (20%), Positives = 291/786 (37%), Gaps = 57/786 (7%)

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTI 1377
            ++I+  +  K  +  K S       L  +    T+   Y+ R+  EN  G         +
Sbjct: 6817 QYILERREKKSLRWVKVSSKRAITELRHRVTNLTEGNEYEFRVMAENGAGVGPASSTSRL 6876

Query: 1378 L---DKPSPPGKPNILE-IDS--SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
                +  S P  P +++ IDS  SS+ I W +P   G   II Y ++  +    EW  V 
Sbjct: 6877 FKCREPTSAPSAPTVIKVIDSTKSSVTIEWTKPVFDGGMEIIGYNIDMCKASLEEWHRVN 6936

Query: 1432 N--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
            +     T+ + + L     Y+FR  AVN     +AS      + +         ++   K
Sbjct: 6937 SQICIHTRYTAKGLVPGELYKFRVSAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFK 6996

Query: 1490 NITTEPN-EDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXX-XXXXXX 1546
               T  N   + L   F G P P  TW + DG+    A     N                
Sbjct: 6997 QTHTVKNGGTVTLQVAFRGKPAPLATWSKADGELPIMADVNTTNTSSTLTIEGCTRYEAG 7056

Query: 1547 XYKCIAFNDHGEVETSCVVGI--------------QQKPVITISNEDIKQKHKVGDEWLV 1592
             Y     N+ G    +  + +                +P+I        ++  V D    
Sbjct: 7057 KYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEPAPPKRLDVIDTTSS 7116

Query: 1593 TAVIEGIPP-----PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
            TA +  + P       +  Y    + +   ++ ++ + K+  + ++ L  +    + ++A
Sbjct: 7117 TASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVEGLIENREYDFRVKA 7176

Query: 1648 SNTAGTSSVEVTL-KVYDKPSKPEGPVIMREISRESVTIEWKP------PLDDGGLELTK 1700
             N AG S  + T   V  K  + E    +  I+ + +T +         P+         
Sbjct: 7177 KNDAGISEPQGTFGSVVIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVI 7236

Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760
            + +E+ +      I +   D +  T  ++    +    + ++ +N  G      +  +V 
Sbjct: 7237 WKLEEMKLKETDRILIRTTD-ERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVTVAVVG 7295

Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK-XXXX 1818
            +     PS          + +ES  ++W     +GG+ I +Y VE ++ G   W+     
Sbjct: 7296 R-----PSPPTGPVEVSGVSSESCTLSWSEPADDGGTDITNYIVEKRESGSASWQVVNSS 7350

Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                  ++  L+    Y FR+ A N+ G S    S   + I      PS P    V   +
Sbjct: 7351 VKRTTIKVTHLTKYMEYTFRVCAENKFGVSKSVES-TPVVIKHPFVAPSPPTRPDVVSVS 7409

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
            + ++ +KW  P ++GGS IT Y IE K      W +   +      + + N+ E  E  F
Sbjct: 7410 ANAIGIKWDVPYADGGSKITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQF 7469

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
            R+ A N  G+S  +E+    L   A  P  P    E+  +  +     W  P  DGG+ +
Sbjct: 7470 RVYAMNIAGLSKASEASRPIL---ALNPVDPPGKPEVTDITRSSASLCWTVPFNDGGSKI 7526

Query: 1999 LGYNI-----AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-SEP 2052
            +GY +     +  +     W++     +    F +  LSE  TY   + A+N  G+ S  
Sbjct: 7527 VGYVVERKVYSADEWDDNRWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGVHSAA 7586

Query: 2053 LESDEP 2058
             ES  P
Sbjct: 7587 SESSGP 7592



 Score =  118 bits (283), Expect = 2e-24
 Identities = 123/544 (22%), Positives = 214/544 (39%), Gaps = 66/544 (12%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G+   ++  I G P P+V+WYK+G ++  DK   I                       
Sbjct: 6637 RAGENVRLSCSITGRPVPQVVWYKDGKEI--DKRIMID---------------------- 6672

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            IE S   GT++          P   EGP+    I+ E  T+ W PP +DG   +T Y +E
Sbjct: 6673 IEISTGIGTNT----------PGPVEGPIRFTGITAEKCTVWWNPPENDGCSAITHYVVE 6722

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            K E     W  V     +  +Y    L +  EY FR+ A N  G  + L+S+P++ +   
Sbjct: 6723 KRETSRISWALVTS-KCEACSYNATNLIKGNEYQFRISAVNKFGVGKPLDSDPVIAQMQY 6781

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXX 1823
             VP             N S+ + W     +GG+ I  Y +E +++   +W          
Sbjct: 6782 TVPDAPGTPDATHVTGN-SITMCWTRPRSDGGNEIKQYILERREKKSLRWVKVSSKRAIT 6840

Query: 1824 A---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880
                R+  L+    Y+FR+ A N  G     ++       +  + PS P    V +ST  
Sbjct: 6841 ELRHRVTNLTEGNEYEFRVMAENGAGVGPASSTSRLFKCREPTSAPSAPTVIKVIDSTKS 6900

Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
            SVT++WT+P  +GG  I  Y I+      + W ++ +       +  + +   +   FR+
Sbjct: 6901 SVTIEWTKPVFDGGMEIIGYNIDMCKASLEEWHRVNSQICIHTRYTAKGLVPGELYKFRV 6960

Query: 1941 SAENTVGVS----LPTESQSV------------RLEKHATVPSPPTAPLEIRMVGSNIVM 1984
            SA N  G      +P   Q++              ++  TV +  T  L++   G    +
Sbjct: 6961 SAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFKQTHTVKNGGTVTLQVAFRGKPAPL 7020

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
             +W   + DG  P++  ++   + + T+ +E   + +      ++ + S   +    I  
Sbjct: 7021 ATWS--KADGELPIMA-DVNTTNTSSTLTIEGCTRYEAGKYTLSLENNSGRKSITFTIKV 7077

Query: 2044 RNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDAD 2102
             +  G   P+     FK +  E   A EEP     +             WL+ EH+  + 
Sbjct: 7078 LDTPGPPGPI----AFKDMT-EPIIATEEPAPPKRLDVIDTTSSTASLVWLKPEHDGGSR 7132

Query: 2103 IRSY 2106
            IR Y
Sbjct: 7133 IRGY 7136



 Score =  114 bits (275), Expect = 2e-23
 Identities = 80/304 (26%), Positives = 129/304 (42%), Gaps = 9/304 (2%)

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822
            LD P           +  E   ++W    ++GG  +  Y VE ++  +  W         
Sbjct: 7696 LDTPGPPADKIVISRVTEEKCTVSWKIPLEDGGDSVTHYVVERRETSRLNWVLVEAECKT 7755

Query: 1823 XARIQ-KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
             + +  +L  N  Y FR+   N+ G  +P  S+  I      T PSQP     +      
Sbjct: 7756 LSCVSSRLIKNNEYIFRVRGVNKFGPGVPLESEPVIA-RNAYTIPSQPGTPETTAVGKEH 7814

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRI 1940
            V ++W +PES+GGS I+NYI++ +      WT++            +  + E  E  FR+
Sbjct: 7815 VIIEWLKPESDGGSEISNYIVDKREKSSTRWTRVNKTYTIYDTRLKVTGLLEGSEYQFRV 7874

Query: 1941 SAENTVGVSLPTESQSVRLEKHAT-VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            +A N  G S P+++    L +  T  P+PP+ P        +I MT W  P +DGG+ + 
Sbjct: 7875 TAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRITDTTKHSISMT-WTRPMYDGGSDVS 7933

Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESD 2056
            GY + I +     W       + T +F    L+ N  Y  R+ A N  G    S+P    
Sbjct: 7934 GYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKKYRFRVAALNSKGTGEFSDPSSEV 7993

Query: 2057 EPFK 2060
            EP +
Sbjct: 7994 EPLE 7997



 Score =  113 bits (272), Expect = 5e-23
 Identities = 107/453 (23%), Positives = 183/453 (40%), Gaps = 36/453 (7%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV--EVTLKVYDKPSKPEGP--VIMREISRE 1681
            K +  ++ +L + +   + +   N  G          K  D  + P  P  V +  ++ E
Sbjct: 4602 KATTCKVTKLLKGNEYIFRVRGVNKYGDGEPLESEPTKAMDPFTVPTPPTNVQVTAVTSE 4661

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
            ++TI W+ P+ DGG  ++ Y IEK E    RW +V              L E CEY +RV
Sbjct: 4662 AMTICWERPVSDGGSSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRV 4721

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT--WFPSEKNGGSPI 1799
             A+N  G S    S P  +  A D             +D+    +T  W     +GG+P+
Sbjct: 4722 FAENSAGLSAP--SIPCPLIKAEDPQFLPSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPV 4779

Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
              Y+VE ++    +W             + KL+    Y F I + N+IG S P    DK 
Sbjct: 4780 TGYRVEYRKTLDDEWVVAVQNTKNTEFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDKQ 4839

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK--- 1914
               +    P     F +S    +++ +K      +G S       + K V   +W K   
Sbjct: 4840 VAKEREEEPV----FEISNEMRKTLIVK------DGSSFTMTVPFKGKPVPTVTWNKPDV 4889

Query: 1915 ------IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
                  ++    +     +E    +D   + ++  N  G +  + + +VR+      P  
Sbjct: 4890 DLRVRAVIDTTDTFTSISLEQANREDSGKYTVTLSNVAGTT--SLALNVRV---LDSPGA 4944

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
            P A +E++ V  +    +W TPE +GG P+  Y + IR+ +K  W  +     + L + +
Sbjct: 4945 P-ARVEVKDVTKSSATVTWDTPENEGGGPVKNYLVDIREASKKGWTRLTDT-CHRLTYKV 5002

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +L E   Y  R+   NE G   P E+ E  K+
Sbjct: 5003 TNLQEGGVYYFRVTGENEYGTGLPAETKEGTKI 5035



 Score =  113 bits (271), Expect = 7e-23
 Identities = 73/259 (28%), Positives = 121/259 (46%), Gaps = 11/259 (4%)

Query: 1210 ANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
            +NT   L  E P  D    ++ Y+ +   +D+E +T+ + VK    +I    + ++ ++ 
Sbjct: 1236 SNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVKALETVIPNLLKGEEYQFK 1295

Query: 1268 CVLLDAKSTT---KLKVEVVE----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
               ++ K  +   +L   VV       P +      Y ++ G D+ + V     P+P   
Sbjct: 1296 VSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLKIEVPIAGHPKPTIA 1355

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W  +   +K+      +  +   +LTIK     D G+Y + + N  G  D  + V ILDK
Sbjct: 1356 WTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNALGCKDATIEVIILDK 1415

Query: 1381 PSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT 1438
            P PP G   + EI + SI + W+ P  TG   I  YVVE ++  TT W+ V   + +T  
Sbjct: 1416 PGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTTNWMVVSATVARTTL 1475

Query: 1439 SIQNLKTNSSYRFRAYAVN 1457
             I NLKT + Y+FR +A N
Sbjct: 1476 KIGNLKTGAEYQFRIFAEN 1494



 Score =  112 bits (269), Expect = 1e-22
 Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 2/200 (1%)

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
            K L  P  P +  V++ T+    L W  P  +GG+ I  +II+ +     +WT + T   
Sbjct: 287  KVLDRPGPPDSLTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAWTNVAT-DL 345

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
              +   +  + + +E IFR+ A N  GV  P ES+ V +  +  VPS P    E+  +  
Sbjct: 346  QANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV-ICTNPYVPSDPPGQPEVTTITK 404

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + ++  W  PE DGG+ +  Y I  RD T   W++  K  V  L+F +  L+  H Y  R
Sbjct: 405  DSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTVTDLRFKVSGLTLGHEYEFR 464

Query: 2041 IYARNEIGLSEPLESDEPFK 2060
            ++A N  GLS+P  S   +K
Sbjct: 465  VFAENNAGLSQPSLSSPFYK 484



 Score =  108 bits (259), Expect = 2e-21
 Identities = 105/419 (25%), Positives = 170/419 (40%), Gaps = 26/419 (6%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P   V +  I+++S+ + W+ P +DGG  +  Y +EK + D  RW +          + +
Sbjct: 833  PPTDVEVSTITKDSMVVTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSELRFRV 892

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE--SVYI 1786
              L EN  Y FRV A+N  G      S+P V   ALD             +D    +V +
Sbjct: 893  TGLLENHSYEFRVAAENAAGVGTP--SQPTVYYKALDPVFKAGPPNNPKALDTSRSTVTL 950

Query: 1787 TWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXX---XXXXXXARIQKLSINTTYQFRIYAR 1842
             W     +GG  I  Y VE       +W               + KL     YQFR+ A 
Sbjct: 951  IWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQFRVCAI 1010

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS--RSVTLKWTEPESNGGSPITNY 1900
            N++G         K+ +   L  P    +  + +  +   + TL+   P     +P   +
Sbjct: 1011 NKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIKW 1070

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
                  +K    T  V V GS     IEN+   D   + ++AEN  G    +   SVR+ 
Sbjct: 1071 GKADGEIKE---TAQVDVTGSYASLVIENVDRFDSGKYTLTAENASGTK--SAFISVRV- 1124

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
                 PSPP+    ++ +  N V  +W  P  DGG+ +  Y +  R+ T+ ++  +    
Sbjct: 1125 --LDSPSPPSN-FTVKEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSPI--TT 1179

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
             N + + +  L E   +  R+ A NE G+  P +  EP K+     S   + PG+ T V
Sbjct: 1180 CNRMSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKI-----SEKPQPPGKVTVV 1233



 Score =  107 bits (256), Expect = 4e-21
 Identities = 89/321 (27%), Positives = 133/321 (41%), Gaps = 18/321 (5%)

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            F + A NP GF++   +  +     LD P           +  E   + W     +GG+ 
Sbjct: 269  FTLTASNPGGFAKFTFNVKV-----LDRPGPPDSLTVTD-VTAEKCVLNWLHPTHDGGAK 322

Query: 1799 IIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            I +Y +  K+E  +  W            ++ KL     Y FR+ A N+ G   P  S+ 
Sbjct: 323  I-EYFIIQKRETSRLAWTNVATDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 381

Query: 1856 KITIGKTLT--PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
             I     +   PP QP    V+  T  S+ + W  PE +GGS I  Y+IE +   G  W 
Sbjct: 382  VICTNPYVPSDPPGQPE---VTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWV 438

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAP 1972
            K      +     +  +    E  FR+ AEN  G+S P+  S   + E    +P PP  P
Sbjct: 439  KCNKRTVTDLRFKVSGLTLGHEYEFRVFAENNAGLSQPSLSSPFYKAEDTIFMPGPPGNP 498

Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDL 2031
              +    S+I + SW  P +DGG+ + GY +      +  W +   K       F I +L
Sbjct: 499  RVLDTTKSSITL-SWNKPVYDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATSFTITNL 557

Query: 2032 SENHTYMIRIYARNEIGLSEP 2052
             EN  Y I I A N  G+ EP
Sbjct: 558  KENQEYKINISATNCEGVGEP 578



 Score =  104 bits (249), Expect = 3e-20
 Identities = 102/385 (26%), Positives = 158/385 (41%), Gaps = 28/385 (7%)

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            + +EW  P  DGG  +  Y +E+ E ++  W K+         +    L E  EY +RV 
Sbjct: 2113 MVVEWHKPPSDGGSAILGYHLERKEKNSILWTKINKTLIQDCRFKSTPLEEGIEYEYRVY 2172

Query: 1743 AQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
            A+N VG  +  + SE  V +   D P           +   SV + W P + +GGS I  
Sbjct: 2173 AENIVGIGKCSKVSEICVAQDPCDPPG----RPEALIVTRHSVKLRWTPPQYDGGSLITG 2228

Query: 1802 YKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKI 1857
            Y VE +   EGK  K            +  L+ ++ Y FRI A+N  G  S P  S   I
Sbjct: 2229 YVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTGSI 2288

Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK-IV 1916
            T    + PP     +      ++ + +K  E  +          +E K +    W K  V
Sbjct: 2289 TAKDEVDPP----KYETDPMYNQMLVVKAGETFN------LEATVEGKPIPTAQWFKGDV 2338

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRIS-----AENTVGVSLPTESQSVRLE-KHATVPSPPT 1970
             V  S     I+N   K  ++ + +      + T+ ++    ++SV    K    P P  
Sbjct: 2339 EVENSARAE-IKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSE 2397

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
             PL +  V       SW  P  DGGA +  Y I  R+ ++  W  V   D     F +  
Sbjct: 2398 GPLTVSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSS-DCGATMFKVTK 2456

Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055
            L + + Y+ R+ A N+ G+ EPLES
Sbjct: 2457 LLKGNEYIFRVMAVNKYGVGEPLES 2481



 Score =  100 bits (239), Expect = 5e-19
 Identities = 56/198 (28%), Positives = 94/198 (47%), Gaps = 2/198 (1%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            PP  P       +   S++ K   P  +GGS +++YI+E +      WT +     +++ 
Sbjct: 731  PPEGPIAIYGVSNEKCSISWKPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNL 790

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
              I  +   +E IFR+   N  GV  P ES+ +        P+PPT  +E+  +  + ++
Sbjct: 791  K-ITKLLPGNEYIFRVIPVNKYGVGEPLESEPMIARNPFVTPNPPT-DVEVSTITKDSMV 848

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
             +W  P  DGG+P+ GY +  RD     W    K  V+ L+F +  L ENH+Y  R+ A 
Sbjct: 849  VTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSELRFRVTGLLENHSYEFRVAAE 908

Query: 2045 NEIGLSEPLESDEPFKVI 2062
            N  G+  P +    +K +
Sbjct: 909  NAAGVGTPSQPTVYYKAL 926



 Score =   99 bits (238), Expect = 7e-19
 Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 15/199 (7%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG-GS 1921
            + PP +P    V+ +T   VTL WT P+ +GG  +T Y++E    K   W K +  G   
Sbjct: 24   IDPPGKPDVINVTRNT---VTLMWTPPKYDGGHKLTGYVVE----KSGDWWKGLDEGTNH 76

Query: 1922 VH----EHCIENIKEKDEIIFRISAENTVG-VSLPTES-QSVRLEKHATVPSPPTAPLEI 1975
            V+     + + ++ E  +  FR+ A+N+ G V +P+ES + +  +     P PP+ P EI
Sbjct: 77   VNIQGCAYTVTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTP-EI 135

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              V  N V  SW  P  DGG+ + GY +  ++     W+   K  V  L+F ++ LSE  
Sbjct: 136  DNVSRNAVTISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGV 195

Query: 2036 TYMIRIYARNEIGLSEPLE 2054
             Y  R+ A N+ G  EP E
Sbjct: 196  EYEFRVTAENKAGFGEPRE 214



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 71/339 (20%), Positives = 140/339 (41%), Gaps = 11/339 (3%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249
            +E P       + + I + A +   L V +    T ++ W K    I++T +  +     
Sbjct: 1031 LEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYA 1090

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
              +L+I      D  +YT    +A  T    + V V++ P    ++  +   K    +T 
Sbjct: 1091 --SLVIENVDRFDSGKYTLTAENASGTKSAFISVRVLDSPSPPSNFTVKEITKNSVTLTW 1148

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
                         +IV  +   + K   P       S  ++ +       +++  EN  G
Sbjct: 1149 EPPLLDGGSKIRHYIVEKRESTR-KVYSPITTCNRMSWKVEPLPEGGIFFFRVLAENEYG 1207

Query: 1368 ---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                A +   + I +KP PPGK  ++++ ++++++ W++P + G S I +Y VE    D+
Sbjct: 1208 VGLPAKIAEPIKISEKPQPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDS 1267

Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
              W     +   +T I NL     Y+F+  A+N+   SD  +  +   V+    +  P V
Sbjct: 1268 EAWTVCATVKALETVIPNLLKGEEYQFKVSAINDKGKSDPRQLAQ--SVVARDLVIHPAV 1325

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
               +   + +   D+++     G P+P + W +DG  LK
Sbjct: 1326 RPKVSTYSVQVGYDLKIEVPIAGHPKPTIAWTKDGIALK 1364



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 99/417 (23%), Positives = 174/417 (41%), Gaps = 20/417 (4%)

Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
            D  + W KDG  ++ +  + ++      K+ I D + DDAG+Y+    NS  TA   +  
Sbjct: 3005 DPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTITATNSVGTATEEITV 3064

Query: 1194 PSINFTLRLPEFILVPANTDAYLTV--EIPDET--LDVTWYKKKSVIEDTEKFTLISDVK 1249
              ++        + +   +  Y+T+  E P+ T    +  Y  +     T  + ++S   
Sbjct: 3065 IILDKPGPPTGPVKIEEVSSNYVTLSWEPPEYTGGCQINNYIVEKRDTTTTAWQIVSATI 3124

Query: 1250 KRTLI-IRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDV 1305
             RT I + K     + ++     +   KS   +   VV ++P           I   +  
Sbjct: 3125 ARTTIKVTKLKTGIEYQFRVSAENRYGKSPAIVSPAVVAQYPFTQPVAPGTPTISAATKD 3184

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDAGI-YKLRL 1362
            T+ V+++A        ++   I +K K++     ++      T  K    + GI Y+ R+
Sbjct: 3185 TMTVEWKAPTNNGGSPVLGYHIERKEKNSLLWTKLNKLLIPDTHFKTAELEEGIEYEFRV 3244

Query: 1363 --ENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
              EN  G ++   +  +    D   PPG P  +EI  + + + W  P+  G S I  YVV
Sbjct: 3245 YAENMAGLSEASKISESTVARDPCDPPGTPEAIEITRNHVTLQWTRPQYDGGSAITGYVV 3304

Query: 1418 EYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI-SDASETTEYYKVI 1474
            E ++   T W+  S  NI  TQ ++  L  +  Y FR  A N   I S  SE+T      
Sbjct: 3305 ERKKHPDTRWMKASFTNIIDTQFTVTGLTEDCVYEFRVIARNAASICSRPSESTGEITAK 3364

Query: 1475 KETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530
             E +    T++   K++T     E   +   + G P P+V W +DGK++  A    E
Sbjct: 3365 DEIEAPEATMDSKFKDLTIVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRME 3421



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 65/203 (32%), Positives = 92/203 (45%), Gaps = 19/203 (9%)

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
            V L   D P KP+  VI   ++R +VT+ W PP  DGG +LT Y +EK    +  W K  
Sbjct: 19   VALDPIDPPGKPD--VI--NVTRNTVTLMWTPPKYDGGHKLTGYVVEK----SGDWWKGL 70

Query: 1718 D-----VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXX 1770
            D     V+     Y +  L E  +Y FRV A+N  G +  + SE   + T  D   P   
Sbjct: 71   DEGTNHVNIQGCAYTVTDLTEGSQYQFRVRAKNSAG-AVGVPSESTELLTCKDEYGPPGP 129

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQ 1827
                    +   +V I+W    ++GGS I  Y VE K++ G +W           R  +Q
Sbjct: 130  PSTPEIDNVSRNAVTISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQ 189

Query: 1828 KLSINTTYQFRIYARNEIGTSLP 1850
             LS    Y+FR+ A N+ G   P
Sbjct: 190  GLSEGVEYEFRVTAENKAGFGEP 212



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 62/238 (26%), Positives = 99/238 (41%), Gaps = 24/238 (10%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX------XARIQKLSIN 1832
            +   +V + W P + +GG  +  Y VE  + G  WK                 +  L+  
Sbjct: 35   VTRNTVTLMWTPPKYDGGHKLTGYVVE--KSGDWWKGLDEGTNHVNIQGCAYTVTDLTEG 92

Query: 1833 TTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
            + YQFR+ A+N  G   +P  S + +T      PP  P    +   +  +VT+ W  P  
Sbjct: 93   SQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNVSRNAVTISWKRPAQ 152

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            +GGS I  Y +E K  +G  W +            ++ + E  E  FR++AEN  G   P
Sbjct: 153  DGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAENKAGFGEP 212

Query: 1952 TESQSVRLEKHAT---VPS----------PPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996
             E    +LE + T   +PS            TA +EI+    + V+ +  +   DGGA
Sbjct: 213  RE--VFKLEANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGA 268



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 8/130 (6%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVE------VTLK-VYDKPSKPEGPVIMREISRESVT 1684
            + +L      ++ + A N+AG   V       +T K  Y  P  P  P I   +SR +VT
Sbjct: 86   VTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEI-DNVSRNAVT 144

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            I WK P  DGG ++  Y +E+ E    RW++ +        + +Q L+E  EY FRV A+
Sbjct: 145  ISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAE 204

Query: 1745 NPVGFSEALE 1754
            N  GF E  E
Sbjct: 205  NKAGFGEPRE 214



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 9/189 (4%)

Query: 1287 PPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            PPKI D E +Y     +  G   TL       P P+  W+   + I +    +       
Sbjct: 632  PPKI-DLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTDFV 690

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
            A + +K+    D G Y L ++N  G   V +NV +LD+P PP  P  I  + +   +I W
Sbjct: 691  ARIIVKEAIRVDGGQYILLVKNVGGEKSVTINVKVLDRPGPPEGPIAIYGVSNEKCSISW 750

Query: 1402 --DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458
                P   G S + +Y+VE +E     W  V+   +T    I  L   + Y FR   VN+
Sbjct: 751  KPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNLKITKLLPGNEYIFRVIPVNK 810

Query: 1459 VDISDASET 1467
              + +  E+
Sbjct: 811  YGVGEPLES 819



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 7/159 (4%)

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILD 1379
            +I+  +   +   T  + D ++  L + K+   +  I+++   N  G  + +E    I  
Sbjct: 326  FIIQKRETSRLAWTNVATDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVICT 385

Query: 1380 KP----SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNI 1433
             P     PPG+P +  I   S+ +CW+ PE+ G S I  YV+E ++     W+  + + +
Sbjct: 386  NPYVPSDPPGQPEVTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTV 445

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
            T  +  +  L     Y FR +A N   +S  S ++ +YK
Sbjct: 446  TDLRFKVSGLTLGHEYEFRVFAENNAGLSQPSLSSPFYK 484



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 50/228 (21%), Positives = 90/228 (39%), Gaps = 8/228 (3%)

Query: 1273 AKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            ++ST  +  +    PPK      Y +   +K G    L    +  P P  +W      ++
Sbjct: 2282 SESTGSITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVE 2341

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-N 1388
                 +       A L +K     D G Y L L N  G   V  +V +LD+P P   P  
Sbjct: 2342 NSARAEIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLT 2401

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNS 1447
            +  +     ++ W  P + G + + +Y+++ +E     W  V  +   T   +  L   +
Sbjct: 2402 VSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVTKLLKGN 2461

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITTE 1494
             Y FR  AVN+  + +  E+     +++   +   P  E  + NIT +
Sbjct: 2462 EYIFRVMAVNKYGVGEPLESVPV--IMRNPFVPPGPPQELEITNITRD 2507



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 83/385 (21%), Positives = 162/385 (42%), Gaps = 35/385 (9%)

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
            KK + ++   +    GE+S    +S+   +   E P +     L + + + A     L V
Sbjct: 7969 KKYRFRVAALNSKGTGEFSDP--SSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMV 8026

Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
             +      V  ++K  V   +  +   +D     L++ K +  D  +Y     +   K T
Sbjct: 8027 FVTGRPTPVVAWRKTGVELQSRGYIETTD-SYTCLMVEKVSRYDSGKYVVEAENPSGKKT 8085

Query: 1277 TKLKVEVVEFPP-----KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
              + V+V + P      K+ DY RE         ++++ +   P  +    V++ II+K 
Sbjct: 8086 ATILVKVYDTPGPPGSVKVKDYTRE---------SVVITWDV-PSVDGGAHVSNYIIEKR 8135

Query: 1332 KHTKPSIDSKSASL--TIKKVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSP 1383
            +    S  + +     T+ ++   + G+   +++  EN  G     +   +V + + PS 
Sbjct: 8136 EANMKSYKTVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLVCEVPSV 8195

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQ 1441
            P    I+++  SS+ + W++P + G S +  YV+E  ++ +  W  ++    + +Q +I 
Sbjct: 8196 PLDLQIIDVTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIP 8255

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK---PLKNITTEPNED 1498
            +L  N  Y FR  A N    S+  +T      I++ K+  P ++    P K       + 
Sbjct: 8256 SLMENDQYLFRVRATNSRGASEPMDTVTPV-TIQDIKV-IPKIDLSSIPQKVAYVHRGKP 8313

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523
            IEL       P P  +WY  G KLK
Sbjct: 8314 IELRIPVKAKPLPVCSWYFGGVKLK 8338



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 72/308 (23%), Positives = 132/308 (42%), Gaps = 31/308 (10%)

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKF 1242
            T + T   P I         +   A +D  L   I   P  T++  W+K    ++ + + 
Sbjct: 5532 TCVDTYGAPEIEIPQEYLSEVKFRAESDVELKFNIIAKPAPTIE--WFKDGKELKPSVQL 5589

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYR 1298
            +     +  ++ +R  T  +   Y   + +    A +T KL ++    PP     E +++
Sbjct: 5590 SFKHTFESTSVFLRDTTRLNSGSYEVKVKNSLGSACATVKLLIQDKPGPPA---GEIQFK 5646

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKP--SIDSKSASLTIKKVENTD 1354
                 ++T++     +  P DE   +V   I++K + ++   SI S+     I  V    
Sbjct: 5647 KVTADNITIM-----WSPPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCIVNVPRLI 5701

Query: 1355 AG---IYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPEN 1406
             G   I+++R  N  G  D   +  ++ K     PS P KP +  I  S++ + W+ P  
Sbjct: 5702 QGNEYIFRVRGVNKYGIGDPLESEPVIAKNAFVPPSEPSKPKVTMITKSTMTVIWERPAL 5761

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             G S I  Y +E +E  + +W  V    I  T+  + NL  N+ Y+FR  AVN+    + 
Sbjct: 5762 DGGSDIDGYYLEKREKKSLQWFKVVKGTIRDTRQKVSNLVENNEYQFRVCAVNKAGAGNY 5821

Query: 1465 SETTEYYK 1472
            SE ++ Y+
Sbjct: 5822 SEASDLYR 5829



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 1/154 (0%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P+  W  + K ++     +         L  K     D G + L   N  G A    N
Sbjct: 226  PIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPGGFAKFTFN 285

Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNI 1433
            V +LD+P PP    + ++ +    + W  P + G + I Y++++ +E     W +V  ++
Sbjct: 286  VKVLDRPGPPDSLTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAWTNVATDL 345

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
               +  +  L   + Y FR  AVN+  + +  E+
Sbjct: 346  QANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 379



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 63/305 (20%), Positives = 127/305 (41%), Gaps = 19/305 (6%)

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTL 1244
            TA   V+ P I+   +  + ++V A     L   I  + L  V W K+   I +  +  +
Sbjct: 625  TAKDEVDPPKIDLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEI 684

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
             +      +I+++    D  +Y  ++  +  + +  + V+V++ P      E    I   
Sbjct: 685  KNTDFVARIIVKEAIRVDGGQYILLVKNVGGEKSVTINVKVLDRPGPP---EGPIAIYGV 741

Query: 1303 SDVTLLVDYQAFPQPND------EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
            S+    + ++  P   D       +IV  +   +   T      ++ +L I K+   +  
Sbjct: 742  SNEKCSISWKPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNLKITKLLPGNEY 801

Query: 1357 IYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            I+++   N  G  +   +  ++ +     P+PP    +  I   S+ + W+ P N G S 
Sbjct: 802  IFRVIPVNKYGVGEPLESEPMIARNPFVTPNPPTDVEVSTITKDSMVVTWERPANDGGSP 861

Query: 1412 IIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            I  Y+VE ++ D   W   + + +++ +  +  L  N SY FR  A N   +   S+ T 
Sbjct: 862  IQGYIVEKRDKDGVRWTRCNKRTVSELRFRVTGLLENHSYEFRVAAENAAGVGTPSQPTV 921

Query: 1470 YYKVI 1474
            YYK +
Sbjct: 922  YYKAL 926



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 5/108 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW---ISVKNITKTQ 1437
            P PPG P +L+   SSI + W++P   G S I  Y+VE    +  EW      K  T T 
Sbjct: 492  PGPPGNPRVLDTTKSSITLSWNKPVYDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATS 551

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
             +I NLK N  Y+    A N   + + +      K   E ++  P +E
Sbjct: 552  FTITNLKENQEYKINISATNCEGVGEPAAVPGIPKA--EDRLLPPEIE 597



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 63/303 (20%), Positives = 123/303 (40%), Gaps = 18/303 (5%)

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKK-KSVIEDTEKFT 1243
            TA   +E P      +  +  +V A     +  +   + L +V W K  K V + T +  
Sbjct: 3362 TAKDEIEAPEATMDSKFKDLTIVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRME 3421

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302
            + + + +  L ++ C   D   +   L++      + V V V   P   D   E +   G
Sbjct: 3422 VKTTLTRTILTVKDCIRVDGGHFVLKLVNVGGVKMVPVTVKVLDRPGPPDGPLEVK---G 3478

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIK--KVENTDAGI 1357
                    + + P  +    ++  II+K + ++ S   ++ K  +++ K  K+   +  I
Sbjct: 3479 VTAEKCYLHWSHPTHDGGASISHYIIEKRETSRLSWTMVEPKIQAISYKITKLLPGNEYI 3538

Query: 1358 YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
            +++   N  G  +   +  ++ +     PS P  P    I   SI + W+ PE+ G + I
Sbjct: 3539 FRVTAVNKYGVGEPLESEPVIARNPFTTPSAPSTPEASAITRDSIVLTWERPESNGGADI 3598

Query: 1413 IYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
              Y++E ++ D   W   + K +   +  +  L    SY F+  A N   +   S  +EY
Sbjct: 3599 EGYILEKRDKDGVRWTKCNKKRLNDLRFRVTGLTEGHSYEFKVSAENAAGVGKPSAPSEY 3658

Query: 1471 YKV 1473
             KV
Sbjct: 3659 IKV 3661



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 43/171 (25%), Positives = 66/171 (38%), Gaps = 10/171 (5%)

Query: 1358 YKLRLENNCGHADVEMNVTIL-------DKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
            +++R +N+ G   V    T L         P PP  P I  +  +++ I W  P   G S
Sbjct: 97   FRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNVSRNAVTISWKRPAQDGGS 156

Query: 1411 TIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             I  Y VE +E     W+  S + +   +  +Q L     Y FR  A N+    +  E  
Sbjct: 157  DIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAENKAGFGEPREVF 216

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            +    +    I S    K  K +      +I+ T  F  V   K +  RDG
Sbjct: 217  KLEANVTGRPIPSLVWTKDGKELEDTAKMEIK-TFDFHTVLVNKDSLRRDG 266



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 8/151 (5%)

Query: 677  DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKI-KTGEKE 733
            D+   VA+++  +   +V+K+T   ++    + + ++N+ G  E S     ++ K  E+E
Sbjct: 4791 DDEWVVAVQNTKNTEFTVVKLTPGAEY---VFVIKSINKIGVSEPSPESDKQVAKEREEE 4847

Query: 734  PPQVI--EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            P   I  E  K++IV+ G S  ++    G P PT+TW K +  ++        DT +   
Sbjct: 4848 PVFEISNEMRKTLIVKDGSSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTSIS 4907

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            L+    +D G YT+   N  G    +  + V
Sbjct: 4908 LEQANREDSGKYTVTLSNVAGTTSLALNVRV 4938



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 8/121 (6%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-----YQEIDTTEWISVKN 1432
            LD   PPGKP+++ +  +++ + W  P+  G   +  YVVE     ++ +D  E  +  N
Sbjct: 21   LDPIDPPGKPDVINVTRNTVTLMWTPPKYDGGHKLTGYVVEKSGDWWKGLD--EGTNHVN 78

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            I     ++ +L   S Y+FR  A N    +   SE+TE      E     P     + N+
Sbjct: 79   IQGCAYTVTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNV 138

Query: 1492 T 1492
            +
Sbjct: 139  S 139



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 9/133 (6%)

Query: 697  ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGE 750
            IT + + QE    + A+N+ G      +P V+K    + EPP+VI   +  K ++VR G 
Sbjct: 2647 ITKLIEHQEYKVRICAINKLGVGEPTEVPGVVK-PIDKIEPPEVILDSDLRKGIVVRAGG 2705

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            S+ +     G P P I W K +  +        G+ +S   +      D G Y L  ENS
Sbjct: 2706 SMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQLSIDICDKYDAGKYILTLENS 2765

Query: 811  EGIAETSAVITVE 823
             G    SA ++V+
Sbjct: 2766 AG--TKSAFVSVK 2776



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVIL 754
            +T +    E  + V A N +G +   P+   +   +    P       +  ++ GE++ +
Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKI 2996

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENSEG 812
               V+G P P I W K+ + +K     +  +T S T   +K     D G YT+ A NS G
Sbjct: 2997 DIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTITATNSVG 3056

Query: 813  IA-ETSAVITVEEP 825
             A E   VI +++P
Sbjct: 3057 TATEEITVIILDKP 3070



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 7/135 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753
            I N+ K +E  + V A+N +G++  P  L      ++    P V   + +  V+ G  + 
Sbjct: 1283 IPNLLKGEEYQFKVSAINDKGKSD-PRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLK 1341

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITI-LKPKKVKDEGVYTLKAENSE 811
            +   + G+P+PTI W K+   +K     +  D TH  T+ +K     D G+Y +   N+ 
Sbjct: 1342 IEVPIAGHPKPTIAWTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNAL 1401

Query: 812  GIAE-TSAVITVEEP 825
            G  + T  VI +++P
Sbjct: 1402 GCKDATIEVIILDKP 1416



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%)

Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF 2026
            PP  P ++  V  N V   W  P++DGG  L GY +    D  K +      V++    +
Sbjct: 26   PPGKP-DVINVTRNTVTLMWTPPKYDGGHKLTGYVVEKSGDWWKGLDEGTNHVNIQGCAY 84

Query: 2027 NIRDLSENHTYMIRIYARNEIG-LSEPLESDE 2057
             + DL+E   Y  R+ A+N  G +  P ES E
Sbjct: 85   TVTDLTEGSQYQFRVRAKNSAGAVGVPSESTE 116



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 8/100 (8%)

Query: 718  EASLPIVLKIKTGEKEPPQVI--EPLKSMIV-RQGESVILSAQVVGNPRPTITWCKNNKP 774
            E++ P+ +K    + +PP +I  + L+ ++V R GE + L A++ G P P ++W K+ K 
Sbjct: 4437 ESTGPVTVK---DDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPVVSWSKDGKE 4493

Query: 775  VKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENSEG 812
            ++A        T+  T  I++    +D G Y L   N  G
Sbjct: 4494 IEAKARCEITSTNFNTTLIVRDAIRRDSGQYVLTLHNVAG 4533



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 57/254 (22%), Positives = 99/254 (38%), Gaps = 26/254 (10%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI--KTGEKEPPQVIEPLKSMIVRQGE 750
            S L I    +++ G YT+   N  G  S+   +K+    G   P    +  + +I  +  
Sbjct: 7043 STLTIEGCTRYEAGKYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEP 7102

Query: 751  SVILSAQVVGNPRPT--ITWCKNNKP---------VKALPTKSD-----GDTHSITILKP 794
            +      V+     T  + W K             V+     SD     G+T S+ +L  
Sbjct: 7103 APPKRLDVIDTTSSTASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVE 7162

Query: 795  KKVKD-EGVYTLKAENSEGIAE---TSAVITVEEPT-EENAEPPLFINRFQEITVKEKGT 849
              +++ E  + +KA+N  GI+E   T   + ++EP  E  A+     N  Q IT K   +
Sbjct: 7163 GLIENREYDFRVKAKNDAGISEPQGTFGSVVIKEPRIEPTADLSSITN--QLITCKISNS 7220

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              +   ++  P P + W      +  ++ I      E   L++ +     DSG Y  V  
Sbjct: 7221 FTIDIPISGRPAPKVIWKLEEMKLKETDRILIRTTDERTTLLVRD-SKRSDSGKYYLVLE 7279

Query: 910  NSAGKSSHGARVTI 923
            NSAG  +    V +
Sbjct: 7280 NSAGVKTFTVTVAV 7293



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 7/122 (5%)

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVA 854
            K E  + + A N  G+ E  A +  +   E+  E P F    +  + I ++   T++L  
Sbjct: 1000 KLEYQFRVCAINKVGVGE-HADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFV 1058

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             V   P P I W + +  I   ET   +  G    LVI NVD   DSG Y   A N++G 
Sbjct: 1059 PVRGRPTPEIKWGKADGEI--KETAQVDVTGSYASLVIENVD-RFDSGKYTLTAENASGT 1115

Query: 915  SS 916
             S
Sbjct: 1116 KS 1117



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 5/116 (4%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNP 860
            + + A NS+G  E S   +  EP E    P L +  +  + + ++  GT++L+  VT  P
Sbjct: 7973 FRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP 8032

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             P + W R   +   S    +  D     L++  V S  DSG Y   A N +GK +
Sbjct: 8033 TPVVAW-RKTGVELQSRGYIETTDSYTC-LMVEKV-SRYDSGKYVVEAENPSGKKT 8085



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 9/125 (7%)

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQVI---EPLKSMIVR 747
            CS  ++T +K+     + V A N +G +    +  I   +   PP+      P   + VR
Sbjct: 6186 CSC-EVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLSDYPNAELAVR 6244

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804
             G+++ +     G PRP I+W K+N P+K    +  ++  +  ++T+   KK +  G YT
Sbjct: 6245 VGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGAKK-EHAGQYT 6303

Query: 805  LKAEN 809
            L  +N
Sbjct: 6304 LVLDN 6308



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 4/118 (3%)

Query: 489  NEK--IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
            NEK   D  P+    T+++ ++ P F          +G  ++ +  V G P P+I W + 
Sbjct: 2954 NEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKD 3013

Query: 547  TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS-STTELIVEAP 603
               +K +    +  +  +   + I++   +DAG +T  A N+ G A+   T +I++ P
Sbjct: 3014 GQALKETTRLNV-SNTKSSTKIYIKDANKDDAGKYTITATNSVGTATEEITVIILDKP 3070



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  ++ E  + G+P+P I W +    +K +    +  D  +  TL I++   +D G +  
Sbjct: 1337 GYDLKIEVPIAGHPKPTIAWTKDGIALKQTTRVNV-TDSTHQTTLTIKDATRDDGGMYNI 1395

Query: 584  VAKNAAGFASSTTELIV 600
               NA G   +T E+I+
Sbjct: 1396 NISNALGCKDATIEVII 1412



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 11/154 (7%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV-IEPL--KSMIVRQGE 750
            +T + +  +  + ++A N  G  S P           E +PP+   +P+  + ++V+ GE
Sbjct: 2256 VTGLTEDSKYDFRIIAKNAAGAISKPSESTGSITAKDEVDPPKYETDPMYNQMLVVKAGE 2315

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            +  L A V G P PT  W K +  V+  A     + D  ++ ++K     D G YTL   
Sbjct: 2316 TFNLEATVEGKPIPTAQWFKGDVEVENSARAEIKNTDFKALLVVKDAVRVDGGQYTLVLN 2375

Query: 809  NSEGIAETS-AVITVEEPTEENAEPPLFINRFQE 841
            N  G      +V  ++ P    +E PL ++   E
Sbjct: 2376 NVAGTKSVPFSVKVLDRPGP--SEGPLTVSNVTE 2407



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKV--KDEG 801
            IV  GE+ I+ A   G P P + W K+ K V KA P      T + TIL  K     D G
Sbjct: 3383 IVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGG 3442

Query: 802  VYTLKAENSEGIAETSAVITV 822
             + LK  N  G+      + V
Sbjct: 3443 HFVLKLVNVGGVKMVPVTVKV 3463



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 5/126 (3%)

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT--VKEKGTIKLVARVT 857
            E V+ +K+ N  G++E S     +   E   EP   I+     T  VK+  +  +     
Sbjct: 4816 EYVFVIKSINKIGVSEPSPESDKQVAKEREEEPVFEISNEMRKTLIVKDGSSFTMTVPFK 4875

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              PVP++TW + +  +     I       +I L   N +   DSG Y    SN AG +S 
Sbjct: 4876 GKPVPTVTWNKPDVDLRVRAVIDTTDTFTSISLEQANRE---DSGKYTVTLSNVAGTTSL 4932

Query: 918  GARVTI 923
               V +
Sbjct: 4933 ALNVRV 4938



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/126 (21%), Positives = 57/126 (45%), Gaps = 3/126 (2%)

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV--KEKGTIKLVARVT 857
            E  + ++AEN  G +ET  ++      ++   P + +  F   TV  +   T+K    + 
Sbjct: 5112 EYFFRVRAENHAGFSETKEMVNAVVVKDQFECPEINMKNFPHNTVYVRAGSTLKCEIPLM 5171

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              P+P ++  ++N  +  +         ++I++++    +  DSG Y   ASNS+G S  
Sbjct: 5172 GRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVAG-DSGRYDITASNSSGTSKS 5230

Query: 918  GARVTI 923
               + +
Sbjct: 5231 FLNIVV 5236



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T   E  VEG P P   WF+    ++ S   ++  + D  A LV+++    D G +T 
Sbjct: 2314 GETFNLEATVEGKPIPTAQWFKGDVEVENSARAEI-KNTDFKALLVVKDAVRVDGGQYTL 2372

Query: 584  VAKNAAGFAS 593
            V  N AG  S
Sbjct: 2373 VLNNVAGTKS 2382



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 8/118 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHM 690
            I P F        +  G ++ ++  ++  P+P I W   G+ +     ++V+  +S   +
Sbjct: 2975 IHPAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKI 3034

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKEPPQVIEPLKSMIV 746
            Y     I +  K   G YT+ A N  G A+  + +++  K G    P  IE + S  V
Sbjct: 3035 Y-----IKDANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNYV 3087



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 8/115 (6%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
            E E PQ  E L  +  R    V L   ++  P PTI W K+ K +K     S   T   T
Sbjct: 5541 EIEIPQ--EYLSEVKFRAESDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFEST 5598

Query: 791  --ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
               L+     + G Y +K +NS G    SA  TV+   ++   PP    +F+++T
Sbjct: 5599 SVFLRDTTRLNSGSYEVKVKNSLG----SACATVKLLIQDKPGPPAGEIQFKKVT 5649



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 754 LSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           L A V G P P++ W K+ K ++  A       D H++ + K    +D G +TL A N  
Sbjct: 218 LEANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPG 277

Query: 812 GIAE-TSAVITVEEP 825
           G A+ T  V  ++ P
Sbjct: 278 GFAKFTFNVKVLDRP 292



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 34/131 (25%), Positives = 62/131 (47%), Gaps = 7/131 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGES 751
            +T + +  E  + V A+N+ G    A +P  + ++   + P   ++  ++ MI +R   +
Sbjct: 994  VTKLLEKLEYQFRVCAINKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAAST 1053

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + L   V G P P I W K +  +K         +++  +++     D G YTL AEN+ 
Sbjct: 1054 LRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLTAENAS 1113

Query: 812  GIAETSAVITV 822
            G    SA I+V
Sbjct: 1114 G--TKSAFISV 1122



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 21/77 (27%), Positives = 35/77 (45%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  ++    V+  P P  +W+     +K S D      +   + LVIR+    D G +T 
Sbjct: 8311 GKPIELRIPVKAKPLPVCSWYFGGVKLKDSLDRIKIDSNGKYSHLVIRDTTINDTGDYTL 8370

Query: 584  VAKNAAGFASSTTELIV 600
              KNA G A+   ++I+
Sbjct: 8371 EVKNAVGMATELIKVII 8387



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +  E   +G PRP I+W +    +K S+  + +   DN   + +R    E AG +T 
Sbjct: 6246 GQNIHIELPFKGKPRPVISWLKDNLPLKESEKIR-FRTTDNKTAVTVRGAKKEHAGQYTL 6304

Query: 584  VAKN 587
            V  N
Sbjct: 6305 VLDN 6308



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 6/118 (5%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKLVARVTRN 859
            + + A+N+ G     +  T     ++  +PP +       Q + VK   T  L A V   
Sbjct: 2267 FRIIAKNAAGAISKPSESTGSITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGK 2326

Query: 860  PVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            P+P+  W++ + E+ + +    +N D +   L++      +D G Y  V +N AG  S
Sbjct: 2327 PIPTAQWFKGDVEVENSARAEIKNTDFK--ALLVVKDAVRVDGGQYTLVLNNVAGTKS 2382



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            GST++ E  + G P P+++  +    +K +  F      D++  +++RE    D+G +  
Sbjct: 5161 GSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSI-KIILRESVAGDSGRYDI 5219

Query: 584  VAKNAAGFASSTTELIV-EAPLSDHG 608
             A N++G + S   ++V + P +  G
Sbjct: 5220 TASNSSGTSKSFLNIVVLDRPSAPQG 5245



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 17/130 (13%)

Query: 697  ITNVKKFQEGTYTVVAVNREG------EASLPIVLKIKTGEKEPPQVIEPLK----SMIV 746
            +T + + +   Y V+A N  G      E+S P+  K    E  PP+     K    ++ +
Sbjct: 7561 VTGLSEEETYEYHVIAKNAAGVHSAASESSGPVTCK---DEYSPPRAELDSKLVGETVTI 7617

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVY 803
              G  ++L   V G P PT+ W K +K +  L  K   +   T ++ ++K     D G Y
Sbjct: 7618 SAGSDLVLDGAVGGKPEPTVYWSKGDK-ILELGEKYSLTYTATRAMAVIKNCDRSDTGRY 7676

Query: 804  TLKAENSEGI 813
             L  +N+ G+
Sbjct: 7677 CLTVKNASGV 7686



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 4/113 (3%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGT-IKLVARVTRNPVPS 863
            A+NS  +    +  T     +++ +PP  I  ++ +++ V   G  I+L A +T  P+P 
Sbjct: 4425 AKNSAELLSAPSESTGPVTVKDDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPV 4484

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            ++W ++ + I             N  L++ +     DSG Y     N AG  S
Sbjct: 4485 VSWSKDGKEIEAKARCEITSTNFNTTLIVRDAIRR-DSGQYVLTLHNVAGTRS 4536



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 708  YTVVAVNREG--EASLPI--VLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNP 762
            + V A+N +G  E S P   V  ++  E    ++ + LK  + +R G ++ L   V G P
Sbjct: 7973 FRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP 8032

Query: 763  RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             P + W K    +++       D+++  +++     D G Y ++AEN  G    + ++ V
Sbjct: 8033 TPVVAWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKKTATILVKV 8092



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T   E  + G P P + W ++   I  +   ++  + D VA ++++E    D G +  
Sbjct: 650 GETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIK-NTDFVARIIVKEAIRVDGGQYIL 708

Query: 584 VAKNAAGFASSTTELIV 600
           + KN  G  S T  + V
Sbjct: 709 LVKNVGGEKSVTINVKV 725



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 4/80 (5%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            ST++    V G P P+I W +    IK +    +     + A+LVI  V   D+G +T  
Sbjct: 1052 STLRLFVPVRGRPTPEIKWGKADGEIKETAQVDV---TGSYASLVIENVDRFDSGKYTLT 1108

Query: 585  AKNAAGFASSTTEL-IVEAP 603
            A+NA+G  S+   + ++++P
Sbjct: 1109 AENASGTKSAFISVRVLDSP 1128



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            S V+ +  +   P P I WF+    +KPS      +  ++  ++ +R+    ++G++   
Sbjct: 5558 SDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFES-TSVFLRDTTRLNSGSYEVK 5616

Query: 585  AKNAAGFASSTTELIVE 601
             KN+ G A +T +L+++
Sbjct: 5617 VKNSLGSACATVKLLIQ 5633



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 5/127 (3%)

Query: 704  QEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGN 761
            +E  + V+AVN +G++   P++  +   +     +I  L  +  V+ G+ + +     G 
Sbjct: 4026 EEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLLFDTYSVKAGDDLKIDVPFKGR 4085

Query: 762  PRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGI-AETSA 818
            P+P ++W K+ + +K     +     + S  ++K     D G Y +   +S G  +   A
Sbjct: 4086 PQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIA 4145

Query: 819  VITVEEP 825
            VI +++P
Sbjct: 4146 VIILDKP 4152



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 3/99 (3%)

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK 798
            P  ++ VR G ++     ++G P P ++  K+N  +K+ +   ++    SI I+  + V 
Sbjct: 5152 PHNTVYVRAGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVA 5211

Query: 799  -DEGVYTLKAENSEGIAETSA-VITVEEPTEENAEPPLF 835
             D G Y + A NS G +++   ++ ++ P+       LF
Sbjct: 5212 GDSGRYDITASNSSGTSKSFLNIVVLDRPSAPQGPVELF 5250



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 16/83 (19%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
            E+  + +  ++L   +   P P+I W+++ + + PS  ++     E+  + + +  + ++
Sbjct: 5551 EVKFRAESDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFESTSVFLRDT-TRLN 5609

Query: 901  SGDYKCVASNSAGKSSHGARVTI 923
            SG Y+    NS G +    ++ I
Sbjct: 5610 SGSYEVKVKNSLGSACATVKLLI 5632



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVPSI 864
            A N  G+ E + V  V +P ++   P + ++    + I V+  G++++       P P I
Sbjct: 2662 AINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEI 2721

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             W + +  + P +   +   GE+   +  ++  + D+G Y     NSAG  S
Sbjct: 2722 RWAKEDAEL-PGKVQVET--GEDYSQLSIDICDKYDAGKYILTLENSAGTKS 2770



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 7/98 (7%)

Query: 731 EKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
           E +PP++    K   +++V  GE+  L A + G P P++ W K  + +         +T 
Sbjct: 629 EVDPPKIDLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTD 688

Query: 788 SIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            +   I+K     D G Y L  +N  G  E S  I V+
Sbjct: 689 FVARIIVKEAIRVDGGQYILLVKNVGG--EKSVTINVK 724



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 10/123 (8%)

Query: 700  VKKFQEGTY---TVVAVNREGEAS-----LPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            V   + GTY    V AVN +G+        P+  K    E +    ++       R G  
Sbjct: 5897 VSHLKPGTYYFFKVSAVNCKGKGEDIKMYQPVQAKDILEEADLDLDVQMTTQYTARAGRD 5956

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT-HSITILKPKKVKDE-GVYTLKAEN 809
            V +   + G P P +TW + ++ + A    +   T  + T++ PK  +D+ G Y L+ EN
Sbjct: 5957 VEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTERATTLVIPKVTRDDCGKYLLEIEN 6016

Query: 810  SEG 812
              G
Sbjct: 6017 GVG 6019


>UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa|Rep:
            Hemicentin-1 precursor - Homo sapiens (Human)
          Length = 5635

 Score =  235 bits (574), Expect = 1e-59
 Identities = 291/1201 (24%), Positives = 482/1201 (40%), Gaps = 129/1201 (10%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G ++  EC+V+G P P +TW +    +  ++  ++  D+ ++  L ++ +   D G + C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI--LQLKNIHVSDTGRYVC 2363

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            VA N AG      +L V AP S  G+  +                    P   S      
Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRS--------------------PENIS------ 2397

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             V E + + L C    IP P I W FK    V   N SV I S   M    L++      
Sbjct: 2398 -VVEKNSVSLTCEASGIPLPSITW-FKDGWPVSLSN-SVRILSGGRM----LRLMQTTME 2450

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGN 761
              G YT V  N  GE      L +      PP ++    L+ + V++ +SV L+ +V GN
Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLV----PPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506

Query: 762  PRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P P ITW K+ +P+   +A    S G    IT +   +V   G YT  A +  G    S 
Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHIISGGRFLQITNV---QVPHTGRYTCLASSPAGHKSRSF 2563

Query: 819  VITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
             + V   PT             +++TV       LV      P  +ITW+++   +  + 
Sbjct: 2564 SLNVFVSPTIAGVGSD---GNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNR 2620

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL--- 934
             I     G  ++++    D   ++G Y CVA+N AG+      V + +  +     L   
Sbjct: 2621 NIRILPGGRTLQILNAQED---NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGP 2677

Query: 935  ---QKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
                K  + +   T+ LEC+     + S  WY + + +   DH  I   G          
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEA 2735

Query: 990  XXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRKLQDF--------EVKEKDVAI---- 1035
               D G   C+  +   E      V   +P   +KL +           + KDV I    
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 1036 -LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
             L  E N +    + W +DG  +    +K      G  R L I    V D G Y+C+  +
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPL-TSSDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVN 2852

Query: 1094 ES--CTAEVTVVELPPEII----TRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSE 1145
            E+   + +  V  L P II    + L  +     NK+     L+ G    R  W KDG  
Sbjct: 2853 EAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQP 2912

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201
            +   +H +   +G+   L+I +  + D G Y C      G++K    L V  P      +
Sbjct: 2913 LLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK 2970

Query: 1202 LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
              E + V  N    LT E+      D++W K +  I+      ++     RTL I +   
Sbjct: 2971 -SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPG--GRTLQIIRAKV 3027

Query: 1261 DDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE----YRIKRGSDVTLLVDYQAFP 1315
             D  EYTC+ ++    +K K  + V  PP I D++ E      ++ G+ V+L  +  A P
Sbjct: 3028 SDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVP 3087

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P   W  N ++I +  H +   D +   L IKK E +D G Y  R  N  G  D   ++
Sbjct: 3088 PPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHL 3145

Query: 1376 TILDKPS--PPGKPNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKN 1432
             +   PS   P +  I+E  S+ + +  D    TG     I ++  ++ I+ ++ + V+ 
Sbjct: 3146 NVYVPPSIEGPEREVIVETISNPVTLTCDA---TGIPPPTIAWLKNHKRIENSDSLEVRI 3202

Query: 1433 IT-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            ++  ++  I   + + S  +   A N        +  +YY +  +        E P  ++
Sbjct: 3203 LSGGSKLQIARSQHSDSGNYTCIASNM-----EGKAQKYYFLSIQVPPSVAGAEIP-SDV 3256

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXX 1547
            +    E++EL C   G+P P + W +DGK + + +        N                
Sbjct: 3257 SVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGK 3316

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIW 1606
            Y C+A N  GE +    + +   P I  + ++ ++   + D  + +     G PPP++ W
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             KNG  L       +    +  VIRI   + S  + YT  ASN AG  +    L+V+  P
Sbjct: 3377 LKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434

Query: 1667 S 1667
            +
Sbjct: 3435 N 3435



 Score =  215 bits (525), Expect = 1e-53
 Identities = 273/1202 (22%), Positives = 469/1202 (39%), Gaps = 101/1202 (8%)

Query: 500  KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            K TS    + P      +   T +G  V   C+  G P+P + W ++  +I  S      
Sbjct: 971  KTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAK 1027

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
            +      +L +     E++G + C A N AG+A    +L V       G +  +      
Sbjct: 1028 FSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----- 1082

Query: 620  XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
                               KP    V  G ++ L C + ++P P I W  + + I P   
Sbjct: 1083 -----------------QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSP 1125

Query: 680  ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE 739
                + S        +KIT  +    G Y  VA N  G  +  + L +      PP++  
Sbjct: 1126 RHTFLPS------GSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV----PPKIQR 1175

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799
              K + V+ G+ V +     G P P ITW K    +         +      +      D
Sbjct: 1176 GPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSD 1235

Query: 800  EGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
             G+YT  A N  G  ET   + V+E PT E+ EPP +   FQE    ++      A+ T 
Sbjct: 1236 AGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIEFPCPAKGT- 1293

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P+I W  N   ++  E      +   + LVI +V +  D+G+Y CVA N AG +   
Sbjct: 1294 -PKPTIKWLHNGRELTGREPGISILEDGTL-LVIASV-TPYDNGEYICVAVNEAGTTERK 1350

Query: 919  ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREII 976
              + + V  V   K    +      +   L C+   T S    WY +  +++     + +
Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410

Query: 977  QEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTM-----LVVKETIPEFIRKLQDFEVKE 1030
              G+            D G   C  +    TS       ++V  TI       +   V  
Sbjct: 1411 NNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLN 1468

Query: 1031 KDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            +DVA LE ++  +   D+ W +DG+ +       +   RG +  L+++N   +D+G Y C
Sbjct: 1469 RDVA-LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRYQC 1525

Query: 1090 ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDG 1143
             + + +      +   + +PP I        ++    +  ++E  T+G  +  + W+KDG
Sbjct: 1526 TVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDG 1585

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203
              I  S+   L ID K Q L I    + D+  Y+C V N   TA     E S +  + +P
Sbjct: 1586 QPIMSSSQ-ALYID-KGQYLHIPRAQVSDSATYTCHVANVAGTA-----EKSFHVDVYVP 1638

Query: 1204 EFI----LVPANTDAY----LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
              I      P N        LT+E     + +  +TW K    ++  +   + +  KK  
Sbjct: 1639 PMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK-- 1696

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV--DYEREYRIKRGSDVTLLV 1309
            L I    E D+ +Y CV        ++K EV V  PP I   D    + +   + + L  
Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
                 P P   W+ + ++I +    K  ++ +   +   +V NT  G+Y+    N  G  
Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNT--GLYRCMAANTAGDH 1814

Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
              E  VT+   P+         +      +      N   +  I ++ + Q ++T +   
Sbjct: 1815 KKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ--- 1871

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
              N+ K Q+S + L+   +    A     V  + A ET ++ ++      + P++E   K
Sbjct: 1872 -GNL-KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH---EPPSLEDAGK 1926

Query: 1490 --NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENR-XXXXXXXXXXXXX 1545
              N T   +  ++L C   G P P +TWY+D + L  +   T+ NR              
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDA 1986

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              YKC+A N  G  E    + +   P I+ SN  +     V +   +     GIP P + 
Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV--VVNNPVRLECEARGIPAPSLT 2044

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W K+G+ + +     +       ++ +   + S + +YT  A N AG    ++ L+VY  
Sbjct: 2045 WLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1666 PS 1667
            P+
Sbjct: 2104 PN 2105



 Score =  209 bits (511), Expect = 6e-52
 Identities = 270/1179 (22%), Positives = 456/1179 (38%), Gaps = 93/1179 (7%)

Query: 518  PKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575
            PKH     G  V   C  +G P P ITW +  + +    +  +   D    TL I +  P
Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATP 1233

Query: 576  EDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT 635
             DAG +TCVA N AG   +   L V+ P        TV             D+      T
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEP-------PTVE------------DLEPPYNTT 1274

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F ++   Q ++        C     P+P I WL  G E+   E   ++I  D     ++L
Sbjct: 1275 FQERVANQRIE------FPCPAKGTPKPTIKWLHNGRELTGREP-GISILEDG----TLL 1323

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVI 753
             I +V  +  G Y  VAVN  G       LK+      PP +   E + ++ V   +   
Sbjct: 1324 VIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV----PPVIKDKEQVTNVSVLLNQLTN 1379

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L  +V G P P I W K+N  V    T    +   I  L     +D G Y+ KA N  G 
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439

Query: 814  AETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            ++    I V  P      P +    F  E++V     + L  +V   P P I W+++ + 
Sbjct: 1440 SQKYFNIDVLVP------PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKP 1493

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +   +   +  D   + L + N     D G Y+C  SN+AGK +   ++TI +       
Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRN-DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551

Query: 933  HLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
            ++           + LEC+T      +  WY + + I        I +G+          
Sbjct: 1552 NVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVS 1611

Query: 991  XXDVGVIKCIVKDQETST--MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD-- 1046
              D     C V +   +      V   +P  I       + ++ V    + +  + A   
Sbjct: 1612 --DSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNP 1669

Query: 1047 ---VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
               + W +DG  +K   N    E  G  +KL I +    D G+Y C+    +   E+   
Sbjct: 1670 SPILTWLKDGVPVKANDN-IRIEAGG--KKLEIMSAQEIDRGQYICVATSVAGEKEIKYE 1726

Query: 1103 --VELPPEIITRLQNQK--VNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157
              V +PP I    +     V   N    +  +T      + W KDG  I   +  ++ ++
Sbjct: 1727 VDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN 1786

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTD 1213
            G+K  L I    + + G Y C   N+    K    +TV  P    +  L E ++V     
Sbjct: 1787 GRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPV 1844

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
            A   +        +TW K    + +T +  L      R L I K   +D   YTCV  +A
Sbjct: 1845 ALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903

Query: 1274 KSTTKLKVEV-VEFPPKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
               T+  +++ V  PP + D  +     +   + V L       P P   W  +++++  
Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSG 1963

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
               T  +  ++   + I+  + +DAGIYK    N+ G  ++  ++ +   PS  G  N++
Sbjct: 1964 S--TSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMV 2021

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
             +  ++      E       ++ +          +  + V +  +   ++ + + + + R
Sbjct: 2022 AVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGR 2080

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +   AVN           E  + I       P +    +N++   ++ +EL C    +P 
Sbjct: 2081 YTCVAVNAAG--------EKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPP 2132

Query: 1511 PKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            P +TW +DG  L  K   +  ENR               Y C A N  G+ E +  V I 
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
              P I  S+E  +     G+   +     GIPPP +IW K G+ +  D    +       
Sbjct: 2193 VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR 2252

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             ++I   ++S ++ Y+  ASN AGT+  E  L+VY +P+
Sbjct: 2253 QLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPT 2291



 Score =  200 bits (488), Expect = 3e-49
 Identities = 249/1088 (22%), Positives = 430/1088 (39%), Gaps = 92/1088 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P+ S       V   + + LEC    IP P + WL  G  +    N    +       
Sbjct: 2010 VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR--- 2066

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              +L +T+ +    G YT VAVN  GE    I L++      PP ++   +++ V   ++
Sbjct: 2067 --ILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV----PPNIMGEEQNVSVLISQA 2120

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            V L  Q    P PT+TW K+  P+   P  S  +  S+  ++  +V+D G YT +A N  
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNN 870
            G  E +  + +  P        L      ++TV E   I L+   +  P P++ W  + +
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDEL-----TQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKV 928
             +++ S    +   G   +L I ++  + D+  Y CVASN AG  K  +  +V I     
Sbjct: 2236 PVLTDSMGRVRILSGGR-QLQI-SIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTIT 2293

Query: 929  TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
                H  +   T  GK++ LEC+       +  W  +   +      EI+ EG       
Sbjct: 2294 NSGSHPTEIIVT-RGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQL 2350

Query: 987  XXXXXXDVGVIKCI------VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                  D G   C+      + D++    +    +I    R  ++  V EK+   L  E 
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEA 2410

Query: 1041 NS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESC 1096
            +      + W +DG  +    N       G  R L +  T++ D G+Y+C++R+   E  
Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRILSGG--RMLRLMQTTMEDAGQYTCVVRNAAGEER 2467

Query: 1097 TAEVTVVELPPEII--TRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQ 1153
                  V +PP I+    L++ KV +    T   E+T      + W KDG  +Q      
Sbjct: 2468 KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHH 2527

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSIN--FTLRLPEFI 1206
            +   G+   L+I +  +   G Y+C   +     S+  ++     P+I    +   PE +
Sbjct: 2528 IISGGR--FLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDV 2585

Query: 1207 LVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
             V  N+   L  E        +TW+K  + +E      ++     RTL I    ED+   
Sbjct: 2586 TVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG--GRTLQILNAQEDNAGR 2643

Query: 1266 YTCVLLDAKSTTKLKVEVVEFPPKIVD---------YEREYRIKRGSDVTLLVDYQAFPQ 1316
            Y+CV  +         EV  + P I++           +E +IK  + +TL  +  A P 
Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
             +  W  + + +K   H   +I +   +L IK+ + +D G Y     N  G  +++ +V 
Sbjct: 2704 ASLSWYKDGQPLKSDDHV--NIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVN 2761

Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENT--GNSTIIYYVVEYQEIDTTEWISVKN-I 1433
            I     PP    + EI +        E ++    N   +Y         T  W    + +
Sbjct: 2762 I---QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPL 2818

Query: 1434 TKTQ----------TSIQNLKTNSSYRFRAYAVNEVDISDASETTEY-YKVIKETKIQSP 1482
            T +             I   K   + R+   AVNE       ++ +Y  +V+    I+  
Sbjct: 2819 TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA----GEDSLQYDVRVLVPPIIKGA 2874

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXX 1540
              + P + +T   N+   + C+  G P P+ +W +DG+ L          N         
Sbjct: 2875 NSDLP-EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNT 2933

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                   Y C+A N  G  +    + +   P VI   +E++     V +   +T  + G 
Sbjct: 2934 QITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTV--VVNNFISLTCEVSGF 2991

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            PPP++ W KN   ++ +    I    +T  ++I   K S   +YT  A N AG S  + +
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVPGGRT--LQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049

Query: 1660 LKVYDKPS 1667
            L VY  PS
Sbjct: 3050 LTVYVPPS 3057



 Score =  197 bits (481), Expect = 2e-48
 Identities = 269/1219 (22%), Positives = 480/1219 (39%), Gaps = 120/1219 (9%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            S ++ EC+  G P P ITW++    I  S    +Y D      +   +V   D+ T+TC 
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKGQYLHIPRAQV--SDSATYTCH 1619

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
              N AG A  +  + V  P                        ++EG   T    P  + 
Sbjct: 1620 VANVAGTAEKSFHVDVYVP-----------------------PMIEGNLAT----PLNKQ 1652

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V     + LEC+    P P + WL  G  +  ++NI +            L+I + ++  
Sbjct: 1653 VVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK------LEIMSAQEID 1706

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNP 762
             G Y  VA +  GE  +    K +     PP +   +     IV     + L   V G+P
Sbjct: 1707 RGQYICVATSVAGEKEI----KYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762

Query: 763  RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             PTI W K+ + +               ++   +V + G+Y   A N+ G  +    +TV
Sbjct: 1763 PPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQ 881
              P      P +  +   E  V +   + L       P PSITW ++++ ++ ++  +  
Sbjct: 1823 HVP------PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKI 1876

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-ET 940
               G  +++  T ++   D+G Y CVA+N+AG++     + + V +   ++   K   ET
Sbjct: 1877 QSSGRVLQIAKTLLE---DAGRYTCVATNAAGETQQ--HIQLHVHEPPSLEDAGKMLNET 1931

Query: 941  E-EGKTVILECQTS-HTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
                  V LEC+ + + V    WY + + +SG      +  G+            D G+ 
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS--DAGIY 1989

Query: 998  KCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG 1053
            KC+  +   +T L     +   P          V   +   LE E     A  + W +DG
Sbjct: 1990 KCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDG 2049

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
              +    N       G I  L + +  + D G Y+C+  + +   +  +   V +PP I+
Sbjct: 2050 SPVSSFSNGLQVLSGGRI--LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIM 2107

Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
               QN  V           L + DA+    + W KDG  +       L+I   +  LKI 
Sbjct: 2108 GEEQNVSVLISQAVEL---LCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIE 2162

Query: 1167 DCDLDDAGEYSCEVGN--SKCTAILTVE---EPSINFTLRLPEFILVPANTDAYLTVEIP 1221
            D  + D G Y+CE  N   K      V     P+I  +  L +  ++  N  + L     
Sbjct: 2163 DAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSG 2222

Query: 1222 DETLDVTWYKKKS-VIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
                ++ W KK S V+ D+  +  ++S    R L I    + D   Y+CV  +   T K 
Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSG--GRQLQISIAEKSDAALYSCVASNVAGTAKK 2280

Query: 1280 KVEV-VEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            +  + V   P I +   +  E  + RG  ++L  + Q  P P   W+ +   + K K  +
Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK----PNILE 1391
              I  +   L +K +  +D G Y     N  G  D + ++++   PS  G      NI  
Sbjct: 2341 --ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISV 2398

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
            ++ +S+++   E       +I ++   +        +S+ N  +  +  + L+   +   
Sbjct: 2399 VEKNSVSLTC-EASGIPLPSITWFKDGWP-------VSLSNSVRILSGGRMLRLMQTTME 2450

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGVP 1509
             A     V  + A E     K+   + +  P +  E  L+++  +  + + LTC   G P
Sbjct: 2451 DAGQYTCVVRNAAGEER---KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNP 2507

Query: 1510 QPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             P++TW++DG+ L+  +A +                    Y C+A +  G    S  + +
Sbjct: 2508 VPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567

Query: 1568 QQKPVIT-ISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTK 1624
               P I  + ++   +   V      + V E    PP  + W+K+G  LE+++   I   
Sbjct: 2568 FVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG 2627

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
             +T  ++I   +  ++ +Y+  A+N AG       +KVY  P   +G +    +S + V 
Sbjct: 2628 GRT--LQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVK 2685

Query: 1685 IEWKPPLDDGGLELTKYAI 1703
            I+    L    LE   YAI
Sbjct: 2686 IKVNNTLT---LECEAYAI 2701



 Score =  196 bits (477), Expect = 7e-48
 Identities = 270/1212 (22%), Positives = 474/1212 (39%), Gaps = 118/1212 (9%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568
            P+F+++        GS V   C V+GYP P I W R   +   S+ F +          L
Sbjct: 793  PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             I  ++  D GT+ C A+N  G   S T + V   ++                       
Sbjct: 853  FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP---------------------- 890

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESD 687
            L GI P+ +       V EG  + L C L+A  P P+  W+     ++ +  I+V  +  
Sbjct: 891  LIGISPSVAN------VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS 944

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMI 745
            +H       I  V+    G YT VA N  G    +  +V+ +    +   Q++  +    
Sbjct: 945  LH-------IERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTI---- 993

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
              +G  V L  +  GNP+P++ W K  + +     K S G   S+ ++ P   ++ G Y 
Sbjct: 994  --EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG-EESGEYV 1050

Query: 805  LKAENSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
              A N+ G A+    +TV   P     +  L  ++  EI+V     + L   V   P P 
Sbjct: 1051 CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI 1110

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ITW +  ++ISP           ++++  T      DSG Y CVA+N AG  +   ++ +
Sbjct: 1111 ITWAKETQLISPFSPRHTFLPSGSMKITETRTS---DSGMYLCVATNIAGNVTQAVKLNV 1167

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXX 983
             V     ++   K  + + G+ V + C    T       +K   + +   E         
Sbjct: 1168 HVPPK--IQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT 1225

Query: 984  XXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQD--FEVKEKDVAILE 1037
                     D G+  C+  +     ET   L V+E  P  +  L+       ++ VA   
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQE--PPTVEDLEPPYNTTFQERVANQR 1283

Query: 1038 VEI-----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
            +E       +    + W  +G  +  ++      + G +  L I + + +D GEY C+  
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL--LVIASVTPYDNGEYICVAV 1341

Query: 1093 DESCTAEVTV---VELPPEIITRLQNQKV----NKGNKATFEIELTKGDALVRWFKDGSE 1145
            +E+ T E      V +PP I  + Q   V    N+      E+E T    ++ W+KD  +
Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP-SPIIMWYKDNVQ 1400

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLR 1201
            +  S+ IQ   +GK   LK++    +DAG YSC+     G S+    + V  P       
Sbjct: 1401 VTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTN 1458

Query: 1202 LPEFILVPANTDAYLTVEIPDETL-DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCT 1259
             P  + V  N D  L  ++      D+ W+K  K +        L+   + + L ++   
Sbjct: 1459 FPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD--RGQVLHLKNAR 1516

Query: 1260 EDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFP 1315
             +D+  Y C + +A  K    +K+  +  PP I   +   +  +   S + L  + +  P
Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKL-TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLP 1575

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P   W  + + I         ID K   L I + + +D+  Y   + N  G A+   +V
Sbjct: 1576 MPAITWYKDGQPIMSSSQAL-YID-KGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHV 1633

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWD---EPENTGN-STIIYYVVEYQEIDTTEWISVK 1431
             +   P   G  N+    +  + I      E +  GN S I+ ++ +   +   +     
Sbjct: 1634 DVYVPPMIEG--NLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKAND----- 1686

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE--KPLK 1489
            NI + +   + L+  S+          V  S A E    Y+V     +  P +E      
Sbjct: 1687 NI-RIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEV---DVLVPPAIEGGDETS 1742

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXX 1547
                  N  +EL C   G P P + W +DG+ +  +       N                
Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGL 1802

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
            Y+C+A N  G+ +    V +   P I  S  +E +  K+K      +  +  GIP P + 
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYK---PVALQCIANGIPNPSIT 1859

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W K+   + N  + N+  +    V++I +     + +YT  A+N AG +   + L V++ 
Sbjct: 1860 WLKDDQPV-NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP 1918

Query: 1666 PSKPEGPVIMRE 1677
            PS  +   ++ E
Sbjct: 1919 PSLEDAGKMLNE 1930



 Score =  193 bits (470), Expect = 5e-47
 Identities = 242/1089 (22%), Positives = 423/1089 (38%), Gaps = 92/1089 (8%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L C   + P   I W   G  +  + NI +            L+I N ++   G Y+ VA
Sbjct: 2595 LVCEAYSYPPATITWFKDGTPLESNRNIRILPGG------RTLQILNAQEDNAGRYSCVA 2648

Query: 713  VNREGEASLPIVLK------IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
             N  GE      +K      I  G+   P  + P K + ++   ++ L  +    P  ++
Sbjct: 2649 TNEAGEMIKHYEVKVYIPPIINKGDLWGPG-LSP-KEVKIKVNNTLTLECEAYAIPSASL 2706

Query: 767  TWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            +W K+ +P+K+        + H++ I K  ++ D G YT  A N  G  E    + ++ P
Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQI-KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765

Query: 826  T--EENAEPPLFINRFQEITVKE---KGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
               ++  E    ++  +    K+      I L       P P++TWY++   ++ S+ + 
Sbjct: 2766 PSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVL 2825

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQKSY 938
                G  +++    V+   D+G Y CVA N AG+ S  +  RV +          L +  
Sbjct: 2826 ILPGGRVLQIPRAKVE---DAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEV 2882

Query: 939  ETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
                 K+ ++EC +S + + +  W  + + +   DH + +  GR            D+G 
Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQIT--DIGR 2940

Query: 997  IKCIVKDQETSTMLVVKETI---PEFIR-KLQDFEVKEKDVAILEVEINS-ETADVVWER 1051
              C+ ++   S        +   P  I  K ++  V   +   L  E++     D+ W +
Sbjct: 2941 YVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLK 3000

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPE 1108
            + + IK   N       G  R L I    V D GEY+CI  +++  ++      V +PP 
Sbjct: 3001 NEQPIKLNTNTL-IVPGG--RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPS 3057

Query: 1109 IITR----LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            I       L    V +G   + E E       ++ W+K+G  I  S H+++  DG  Q L
Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QML 3115

Query: 1164 KIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
             I   ++ D G+Y C   N      K   +     PSI    R  E I+   +    LT 
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTC 3173

Query: 1219 E---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            +   IP  T  + W K    IE+++   +        L I +    D   YTC+  + + 
Sbjct: 3174 DATGIPPPT--IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231

Query: 1276 TT-KLKVEVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
               K     ++ PP +   E   +  +  G +V L+ +    P P  +W+ + K I   +
Sbjct: 3232 KAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN---- 1388
              +  + +  ++L I     +D G Y     N  G  D   N+ +   P+  G  +    
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
            ++ +  +SINI   E   TG                  W+         + I+ L     
Sbjct: 3352 LMTLVDTSINI---ECRATGTPP-----------PQINWLKNGLPLPLSSHIRLLAAGQV 3397

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPL--KNITTEPNEDIELTC 1503
             R     V++V +     +       K   +Q    P ++  +  + IT        + C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457

Query: 1504 IFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVET 1561
            I  G P P + W RDG+ L   A  T                    Y CIA N+ GEV  
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSK 3517

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
              ++ + + P I  S E  +    V +   +T +  GIP P++ W K+G  L    +  +
Sbjct: 3518 HFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQ--V 3575

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP--SKPEGPVIMREIS 1679
             T     V+RI   +   + +YT  AS+ AG    E  ++V+  P  +  + P  +  + 
Sbjct: 3576 QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLR 3635

Query: 1680 RESVTIEWK 1688
               VT+E K
Sbjct: 3636 NRQVTLECK 3644



 Score =  184 bits (449), Expect = 2e-44
 Identities = 262/1206 (21%), Positives = 456/1206 (37%), Gaps = 135/1206 (11%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            +G+ +   C+  G P P + W ++ + ++  S              + I E    DA  +
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE--KSDAALY 2267

Query: 582  TCVAKNAAGFASS--TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
            +CVA N AG A      ++ +   +++ GS  T              ++ +GIPP     
Sbjct: 2268 SCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEV-QGIPP----- 2321

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P   ++ +G  ++                 KG EI+ DE               +L++ N
Sbjct: 2322 PTVTWMKDGHPLIKA---------------KGVEIL-DEG-------------HILQLKN 2352

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS---MIVRQGESVILSA 756
            +     G Y  VAVN  G       L +      PP +I   +S   + V +  SV L+ 
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTC 2408

Query: 757  QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            +  G P P+ITW K+  PV    +        +  L    ++D G YT    N+ G    
Sbjct: 2409 EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
               ++V  P     E     N  +++ VKEK ++ L   VT NPVP ITW+++ + +   
Sbjct: 2469 IFGLSVLVPPHIVGE-----NTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQED 2523

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            E       G  ++  ITNV     +G Y C+AS+ AG  S    + + V     +  +  
Sbjct: 2524 EAHHIISGGRFLQ--ITNVQVP-HTGRYTCLASSPAGHKSRSFSLNVFVSPT--IAGVGS 2578

Query: 937  SYETEEGKTVILECQTS--------HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                E+  TVIL   TS           +  W+ +   +    +  I+  GR        
Sbjct: 2579 DGNPED-VTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILN 2635

Query: 989  XXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK-------LQDFEVKEK--DVAILE 1037
                + G   C+  ++  E      VK  IP  I K       L   EVK K  +   LE
Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695

Query: 1038 VEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             E  +  +A + W +DG+ +K   +  +    GH   L I+   + D G Y+C+  + + 
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAG 2752

Query: 1097 TAEVTV---VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDAL-----------VRWF 1140
              E+     +++PP    +  + N      N    ++ +    +L           + W+
Sbjct: 2753 EDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWY 2812

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196
            KDG  +  S+ + +   G+   L+I    ++DAG Y+C    E G       + V  P I
Sbjct: 2813 KDGHPLTSSDKVLILPGGR--VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPI 2870

Query: 1197 --NFTLRLPEFILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
                   LPE + V  N  A +  +         +W K    + + +    +S+   R L
Sbjct: 2871 IKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSN--GRIL 2928

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDY 1311
             I      D   Y CV  +   + K    + V  PP ++  + E   +   + ++L  + 
Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEV 2988

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
              FP P+  W+ N + IK   +T   I     +L I + + +D G Y     N  G +  
Sbjct: 2989 SGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKK 3046

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWIS 1429
            + ++T+   PS      I + DS S+++      N    T +    E   +      W  
Sbjct: 3047 KFSLTVYVPPS------IKDHDSESLSVV-----NVREGTSVSLECESNAVPPPVITWYK 3095

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEK 1486
               +    T ++ L        +   V++             +  K   +     P++E 
Sbjct: 3096 NGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155

Query: 1487 PLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXX 1541
            P + +  E  +  + LTC   G+P P + W ++ K+++ + +                  
Sbjct: 3156 PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y CIA N  G+ +    + IQ  P +  +         +G+   +     GIP 
Sbjct: 3216 HSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT 3275

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P + W K+G  + + +   I      S + I     S + KYT  A+N AG       L 
Sbjct: 3276 PLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN 3335

Query: 1662 VYDKPS 1667
            VY  P+
Sbjct: 3336 VYVTPT 3341



 Score =  180 bits (439), Expect = 3e-43
 Identities = 241/1193 (20%), Positives = 429/1193 (35%), Gaps = 91/1193 (7%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            +T+  EC+    P   ++W++    +K      +     N  TL I+E    D G +TCV
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAA---NGHTLQIKEAQISDTGRYTCV 2746

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            A N AG      ++ ++ P S                     ++L+       +  +A+ 
Sbjct: 2747 ASNIAGEDELDFDVNIQVPPS-------------FQKLWEIGNMLDT-----GRNGEAKD 2788

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V   + I L C   A P P + W   G  +   + + +           VL+I   K   
Sbjct: 2789 VIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGG------RVLQIPRAKVED 2842

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G YT VAVN  GE SL   +++           +  + + V   +S ++     G+P P
Sbjct: 2843 AGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAP 2902

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
              +W K+ +P+             I  +   ++ D G Y   AEN+ G A+    + V  
Sbjct: 2903 RNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P      P +   + + +TV     I L   V+  P P ++W +N + I  +        
Sbjct: 2963 P------PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPG 3016

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET---E 941
            G  ++++   V    D G+Y C+A N AG+S     +T+ V   +   H  +S       
Sbjct: 3017 GRTLQIIRAKVS---DGGEYTCIAINQAGESKKKFSLTVYVPP-SIKDHDSESLSVVNVR 3072

Query: 942  EGKTVILECQTSHTVST--KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            EG +V LEC+++        WY N + I+   H EI+ +G+               V + 
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132

Query: 1000 IV---KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
            I    +D +   + V      E   +    E     V +           + W ++ + I
Sbjct: 3133 INVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRI 3192

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRL 1113
            +   +  +        KL I  +   D G Y+CI  +    A+      +++PP +    
Sbjct: 3193 E-NSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAE 3251

Query: 1114 QNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
                V+       E+          L++W KDG  I      ++ +      L IY    
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALT 3311

Query: 1171 DDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
             D G+Y+C   N      +   +     P+I       E ++   +T   +         
Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPP 3371

Query: 1226 -DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              + W K    +  +    L++    + + I +    D   YTCV  +          + 
Sbjct: 3372 PQINWLKNGLPLPLSSHIRLLA--AGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429

Query: 1285 EFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             F P  +D      E  + +GS  ++       P P+  W+ + + +    H   ++ + 
Sbjct: 3430 VFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHL--TVSTH 3487

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
               L + K E  D+G Y     N  G       + +L+ P   G     EI S  +N   
Sbjct: 3488 GMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEI-SVIVN--- 3543

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD- 1460
                N    T I   +   ++    W+           +Q L      R     V +   
Sbjct: 3544 ----NPLELTCIASGIPAPKMT---WMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGR 3596

Query: 1461 -----ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
                  S A +  + Y V           ++P ++IT   N  + L C    VP P +TW
Sbjct: 3597 YTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP-RDITVLRNRQVTLECKSDAVPPPVITW 3655

Query: 1516 YRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             R+G++L+                          Y C+A N  G+     ++ +   P I
Sbjct: 3656 LRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNI 3715

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRI 1632
                + +     +    ++  + EG+P P + W K+G  L  N   Y+I    +   + I
Sbjct: 3716 KGGPQSLVIL--LNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSIL---ENGFLHI 3770

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            +    + + +Y   A+N AGT    + L+V+  PS   GP  M  I     T+
Sbjct: 3771 QSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTL 3823



 Score =  178 bits (434), Expect = 1e-42
 Identities = 266/1185 (22%), Positives = 444/1185 (37%), Gaps = 112/1185 (9%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            ++ +C V G P P I W +   +I     F++     N   LVI +    + G + C+A 
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILL---NGRKLVIAQAQVSNTGLYRCMAA 1808

Query: 587  NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ-YV 645
            N AG               DH  E  V                  +PPT      ++  V
Sbjct: 1809 NTAG---------------DHKKEFEVTVH---------------VPPTIKSSGLSERVV 1838

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
             +   + L+C    IP P I WL K ++ V     ++ I+S       VL+I        
Sbjct: 1839 VKYKPVALQCIANGIPNPSITWL-KDDQPVNTAQGNLKIQSSGR----VLQIAKTLLEDA 1893

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGESVILSAQVVGNPR 763
            G YT VA N  GE    I L +     EPP + +  K +   V     V L  +  GNP 
Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVH----EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPV 1949

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            P ITW K+N+ +    + +  +   I  ++  ++ D G+Y   A NS G  E    + V 
Sbjct: 1950 PVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                     P        + V     ++L       P PS+TW ++   +S      Q  
Sbjct: 2010 -------VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVL 2062

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
             G  I L +T+     D+G Y CVA N+AG+      + + V      +    S    + 
Sbjct: 2063 SGGRI-LALTSAQIS-DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQA 2120

Query: 944  KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
              ++ +       +  W  +   +        I E R            D G   C   +
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLS-ISENR-SVLKIEDAQVQDTGRYTCEATN 2178

Query: 1004 --QETSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE-II 1056
               +T     V   +P  I    +L    V E ++  L  E +     +++W++ G  ++
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVL 2238

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRL 1113
                 +      G  R+L I      D   YSC+  + + TA+      V + P I    
Sbjct: 2239 TDSMGRVRILSGG--RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSG 2296

Query: 1114 QNQK---VNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
             +     V +G   + E E+       V W KDG  +  +  +++  +G   +LK  +  
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLK--NIH 2354

Query: 1170 LDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            + D G Y C   N      K   +     PSI    R PE I V       LT E     
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414

Query: 1225 L-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVE 1282
            L  +TW+K    +  +    ++S    R L + + T +D  +YTCV+ +A     K+   
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSG--GRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGL 2472

Query: 1283 VVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
             V  PP IV      + ++K    VTL  +    P P   W  + + ++  +     I S
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQ--EDEAHHIIS 2530

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-----PPGKPNILEIDSS 1395
                L I  V+    G Y     +  GH     ++ +   P+       G P  + +  +
Sbjct: 2531 GGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN 2590

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
            S      E  +   +TI ++  +   +++   I +    +T   I N + +++ R+   A
Sbjct: 2591 SPTSLVCEAYSYPPATITWF-KDGTPLESNRNIRILPGGRT-LQILNAQEDNAGRYSCVA 2648

Query: 1456 VNEV-DISDASETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
             NE  ++    E   Y   +I +  +  P +    K +  + N  + L C    +P   +
Sbjct: 2649 TNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSP--KEVKIKVNNTLTLECEAYAIPSASL 2706

Query: 1514 TWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            +WY+DG+ LK+        N                Y C+A N  GE E    V IQ  P
Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766

Query: 1572 ----VITISNE-DIKQKHKVGDEWLVTAV-----IEGIPPPEVIWYKNGNKLENDKEYNI 1621
                +  I N  D  +  +  D  +   +         PPP + WYK+G+ L +  +  I
Sbjct: 2767 SFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI 2826

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                +  V++I   K   + +YT  A N AG  S++  ++V   P
Sbjct: 2827 LPGGR--VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869



 Score =  176 bits (429), Expect = 5e-42
 Identities = 262/1150 (22%), Positives = 439/1150 (38%), Gaps = 122/1150 (10%)

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
            +  A +SD G   T              D+   +PP    + +   V     + L C+  
Sbjct: 2070 LTSAQISDTG-RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
            AIP P + WL  G  ++    +S++         SVLKI + +    G YT  A N  G+
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISENR------SVLKIEDAQVQDTGRYTCEATNVAGK 2182

Query: 719  ASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
                  + I      PP +   + L  + V +G  + L  +  G P P + W K   PV 
Sbjct: 2183 TEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVL 2238

Query: 777  A-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENA 830
                  +   S G    I+I +     D  +Y+  A N  G A+    + V   PT  N+
Sbjct: 2239 TDSMGRVRILSGGRQLQISIAEK---SDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
                  +   EI V    +I L   V   P P++TW ++   +  ++ +    +G  ++L
Sbjct: 2296 G-----SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQL 2350

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ-KSYETEEGKTVILE 949
               +V    D+G Y CVA N AG +     +++         H   ++    E  +V L 
Sbjct: 2351 KNIHVS---DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLT 2407

Query: 950  CQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--E 1005
            C+ S     S  W+ +   +S  +   I+  GR            D G   C+V++   E
Sbjct: 2408 CEASGIPLPSITWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465

Query: 1006 TSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKN 1061
               +  +   +P  I     L+D +VKEK    L  E+  +   ++ W +DG+ ++ +  
Sbjct: 2466 ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQ-EDE 2524

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELP----------P 1107
             +     G  R L I N  V   G Y+C+       +S +  + V   P          P
Sbjct: 2525 AHHIISGG--RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
            E +T + N   +   +A      +   A + WFKDG+ ++ + +I++   G+   L+I +
Sbjct: 2583 EDVTVILNSPTSLVCEA-----YSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILN 2635

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVE-----EPSIN----FTLRL-PEFILVPANTDAYLT 1217
               D+AG YSC   N     I   E      P IN    +   L P+ + +  N    L 
Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695

Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
             E   IP  +L  +WYK    ++  +   + ++    TL I++    D   YTCV  +  
Sbjct: 2696 CEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN--GHTLQIKEAQISDTGRYTCVASNIA 2751

Query: 1275 STTKLKVEV-VEFPP---------KIVDYEREYRIKR---GSDVTLLVDYQAFPQPNDEW 1321
               +L  +V ++ PP          ++D  R    K     + ++L  +  A P P   W
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTW 2811

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              +   +      K  I      L I + +  DAG Y     N  G   ++ +V +L  P
Sbjct: 2812 YKDGHPL--TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869

Query: 1382 SPPGKPNILE------IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
               G  + L       ++ S++  C         ++         E D  +++S   I +
Sbjct: 2870 IIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQ 2929

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
                I N +     R+   A N      A    +Y+ +     +    +    +N+T   
Sbjct: 2930 ----ILNTQITDIGRYVCVAEN-----TAGSAKKYFNL--NVHVPPSVIGPKSENLTVVV 2978

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            N  I LTC   G P P ++W ++ +  KL T                       Y CIA 
Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAI 3038

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611
            N  GE +    + +   P I   + +      V +   V+   E   +PPP + WYKNG 
Sbjct: 3039 NQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGR 3098

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS--KP 1669
             +       I    +  ++ IK+ + S + +Y   A N AG       L VY  PS   P
Sbjct: 3099 MITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP 3156

Query: 1670 EGPVIMREIS 1679
            E  VI+  IS
Sbjct: 3157 EREVIVETIS 3166



 Score =  173 bits (422), Expect = 3e-41
 Identities = 232/1115 (20%), Positives = 425/1115 (38%), Gaps = 83/1115 (7%)

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653
            S   L +E      G E T               ++  + PT     +     EG  + L
Sbjct: 941  SDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTL 1000

Query: 654  ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
             C+    P+P + W  KGE ++   +   +  +D  +Y     + +    + G Y   A 
Sbjct: 1001 PCKASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLY-----VVSPGGEESGEYVCTAT 1054

Query: 714  NREGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
            N  G A   + L +       G++      +P++  ++  GE V L  +V   P P ITW
Sbjct: 1055 NTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITW 1113

Query: 769  CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
             K  + +     +          +   +  D G+Y   A N  G    +  + V  P + 
Sbjct: 1114 AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKI 1173

Query: 829  NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGEN 887
               P     +  ++ V ++  I   A+ T  P+P ITW +    ++   E    N DG  
Sbjct: 1174 QRGP-----KHLKVQVGQRVDIPCNAQGT--PLPVITWSKGGSTMLVDGEHHVSNPDGT- 1225

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-----E 942
              L I       D+G Y CVA+N AG       +T+ V++   V+ L+  Y T       
Sbjct: 1226 --LSIDQATPS-DAGIYTCVATNIAGTDE--TEITLHVQEPPTVEDLEPPYNTTFQERVA 1280

Query: 943  GKTVILECQTSHTV--STKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKC 999
             + +   C    T   + KW HN +E++G +    I+++G             D G   C
Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYIC 1338

Query: 1000 IVKDQETST--MLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
            +  ++  +T     +K  +P  I+   ++ +  V    +  L  E+    + ++ W +D 
Sbjct: 1339 VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN 1398

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
              +  + +       G I KL+    +  D G YSC   + + T++      V +PP II
Sbjct: 1399 VQVT-ESSTIQTVNNGKILKLF--RATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTII 1455

Query: 1111 -TRLQNQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
             T   N+  V        E ++ KG     + WFKDG  + F     + +  + Q L + 
Sbjct: 1456 GTNFPNEVSVVLNRDVALECQV-KGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLK 1513

Query: 1167 DCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            +   +D G Y C V N+         LT+  P       +   I V  N+   L  E   
Sbjct: 1514 NARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRG 1573

Query: 1223 ETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
              +  +TWYK    I  + +   I   K + L I +    D   YTC + +   T +   
Sbjct: 1574 LPMPAITWYKDGQPIMSSSQALYID--KGQYLHIPRAQVSDSATYTCHVANVAGTAEKSF 1631

Query: 1282 EVVEFPPKIVDYEREYRIKR----GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
             V  + P +++      + +       +TL       P P   W+ +   +K   + +  
Sbjct: 1632 HVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR-- 1689

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
            I++    L I   +  D G Y     +  G  +++  V +L  P+  G            
Sbjct: 1690 IEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVN 1749

Query: 1398 NICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            N+   +   TG+    I ++ + Q ID  +   +  +   +  I   + +++  +R  A 
Sbjct: 1750 NLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKIL-LNGRKLVIAQAQVSNTGLYRCMAA 1808

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTW 1515
            N           ++ K  + T    PT++   L        + + L CI  G+P P +TW
Sbjct: 1809 NTAG--------DHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITW 1860

Query: 1516 YRDGKKLKTAKATYENRXX---XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             +D + + TA+   + +                  Y C+A N  GE +    + + + P 
Sbjct: 1861 LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            +  + + + +   V +   +     G P P + WYK+   L      ++T   +  +I I
Sbjct: 1921 LEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRGQIIDI 1978

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +  + S +  Y   A N+AG + +  +L+V+  PS
Sbjct: 1979 ESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS 2013



 Score =  173 bits (421), Expect = 4e-41
 Identities = 252/1208 (20%), Positives = 458/1208 (37%), Gaps = 111/1208 (9%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            S     C+   YP   ITWF+    ++ +++ ++        TL I     ++AG ++CV
Sbjct: 2591 SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQEDNAGRYSCV 2647

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            A N AG      E+ V  P   +  ++                      P  S  PK   
Sbjct: 2648 ATNEAGEMIKHYEVKVYIPPIINKGDLW--------------------GPGLS--PKEVK 2685

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            +   + + LEC   AIP   ++W   G+ +  D+++++A           L+I   +   
Sbjct: 2686 IKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH------TLQIKEAQISD 2739

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIV--RQGES--------V 752
             G YT VA N  GE  L   + I+     PP  Q +  + +M+   R GE+        +
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQV----PPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             L  +    P PT+TW K+  P+ +           +  +   KV+D G YT  A N  G
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855

Query: 813  IAETSAVITVEEPT---EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
                   + V  P      N++ P      +E+TV    +  +    + +P P  +W ++
Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLP------EEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + +   +      +G  ++++ T +    D G Y CVA N+AG +     + + V   +
Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQIT---DIGRYVCVAENTAGSAKKYFNLNVHVPP-S 2965

Query: 930  FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             +    ++        + L C+ S        W  N++ I    +  I+  GR       
Sbjct: 2966 VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRA 3025

Query: 988  XXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIR-----KLQDFEVKEKDVAILEVEI 1040
                 D G   CI  +Q  E+     +   +P  I+      L    V+E     LE E 
Sbjct: 3026 KVS--DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECES 3083

Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            N+    V+ W ++G +I    +    E     + L+I+   V D G+Y C   + +   +
Sbjct: 3084 NAVPPPVITWYKNGRMITESTH---VEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD 3140

Query: 1100 VTV---VELPPEIITRLQNQKVNK-GNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQL 1154
                  V +PP I    +   V    N  T   + T      + W K+   I+ S+ +++
Sbjct: 3141 KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEV 3200

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPA 1210
             I     KL+I      D+G Y+C   N +  A     L+++ P       +P  + V  
Sbjct: 3201 RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLL 3260

Query: 1211 NTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              +  L        T  + W K    I   E   +       TL I      D  +YTCV
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320

Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNS 1325
              +   +      + V   P    + +   ++    D ++ ++ +A   P P   W+ N 
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNG 3380

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP- 1384
              +    H +  + +    + I + + +D  +Y     N  G  +   N+ +   P+   
Sbjct: 3381 LPLPLSSHIR--LLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN 3438

Query: 1385 --GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
              G   I  +  SS ++          S  + ++ + Q +     ++V         +  
Sbjct: 3439 SMGTEEITVLKGSSTSMACITDGTPAPS--MAWLRDGQPLGLDAHLTVSTHGMV-LQLLK 3495

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
             +T  S ++   A NE     A E ++++  KV++   I      + +  I   P   +E
Sbjct: 3496 AETEDSGKYTCIASNE-----AGEVSKHFILKVLEPPHINGSEEHEEISVIVNNP---LE 3547

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            LTCI  G+P PK+TW +DG+ L       T                   Y C+A +  G+
Sbjct: 3548 LTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             +   +V +   P I  ++E          +  +    + +PPP + W +NG +L+    
Sbjct: 3608 DDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR 3667

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
              I +  +   ++I       ++ YT  ASN AG ++ E  L V   P+   GP  +  +
Sbjct: 3668 VRILSGGR--YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVIL 3725

Query: 1679 SRESVTIE 1686
              +S  +E
Sbjct: 3726 LNKSTVLE 3733



 Score =  165 bits (402), Expect = 9e-39
 Identities = 238/1078 (22%), Positives = 414/1078 (38%), Gaps = 81/1078 (7%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G PP F ++P    ++ GS++ L C +   PEP I W  +  + +P  +   ++ S   +
Sbjct: 790  GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L I N+    +GTY   A N+ G+      + + TG   P   I P  + ++   +
Sbjct: 848  RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV-TGLVAPLIGISPSVANVIEGQQ 906

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKA 807
              +    + GNP P   W KN+  +   P    +SDG  H    ++  +++D G YT  A
Sbjct: 907  LTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLH----IERVQLQDGGEYTCVA 962

Query: 808  ENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
             N  G   +T++V+    PT ++ +        Q ++  E   + L  + + NP PS+ W
Sbjct: 963  SNVAGTNNKTTSVVVHVLPTIQHGQ--------QILSTIEGIPVTLPCKASGNPKPSVIW 1014

Query: 867  YRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
             +  E+IS S    +   DG    L + +   E +SG+Y C A+N+AG +    ++T+ V
Sbjct: 1015 SKKGELISTSSAKFSAGADG---SLYVVSPGGE-ESGEYVCTATNTAGYAKRKVQLTVYV 1070

Query: 926  EKVTF--VKHLQKSYETE----EGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQ 977
                F   + L +    E     G+ V L C+          W    + IS    R    
Sbjct: 1071 RPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFL 1130

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVA 1034
                           D G+  C+  +   +    VK  +   P+  R  +  +V+     
Sbjct: 1131 P--SGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRV 1188

Query: 1035 ILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
             +          V+ W + G  +      +     G    L I   +  D G Y+C+  +
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATPSDAGIYTCVATN 1245

Query: 1094 ESCTAEV----------TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDG 1143
             + T E           TV +L P   T  Q +  N+  +     + T     ++W  +G
Sbjct: 1246 IAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTP-KPTIKWLHNG 1304

Query: 1144 SEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINF 1198
             E+      I +  DG    L I      D GEY C    E G ++    L V  P +  
Sbjct: 1305 RELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIK 1362

Query: 1199 TLRLPEFILVPAN--TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256
                   + V  N  T+ +  VE     + + WYK    ++ TE  T+ +    + L + 
Sbjct: 1363 DKEQVTNVSVLLNQLTNLFCEVEGTPSPI-IMWYKDN--VQVTESSTIQTVNNGKILKLF 1419

Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV--DYEREYRIKRGSDVTLLVDYQA 1313
            + T +D   Y+C  ++   T++    + V  PP I+  ++  E  +    DV L    + 
Sbjct: 1420 RATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKG 1479

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P P+  W  + K +         +D +   L +K     D G Y+  + N  G    ++
Sbjct: 1480 TPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKN 1432
             +TI   PS  G     +I     ++   E E  G     I +  + Q I ++       
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALY 1596

Query: 1433 ITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            I K Q   I   + + S  +  +  N   ++  +E + +  V     I+   +  PL N 
Sbjct: 1597 IDKGQYLHIPRAQVSDSATYTCHVAN---VAGTAEKSFHVDVYVPPMIEG-NLATPL-NK 1651

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYK 1549
                   + L C   G P P +TW +DG  +K                          Y 
Sbjct: 1652 QVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYI 1711

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            C+A +  GE E    V +   P I   +E       V +   +   + G PPP ++W K+
Sbjct: 1712 CVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKD 1771

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            G  ++    + I    +  V  I + + S++  Y   A+NTAG    E  + V+  P+
Sbjct: 1772 GQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPT 1827



 Score =  164 bits (399), Expect = 2e-38
 Identities = 241/1072 (22%), Positives = 409/1072 (38%), Gaps = 79/1072 (7%)

Query: 632  IPPTFS--KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +PP+ +  + P    V  G ++ L C    IP P I WL  G+ I   E   + + ++  
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG- 3301

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               S L I        G YT VA N  GE      L +           E  K M +   
Sbjct: 3302 ---STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD- 3357

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             S+ +  +  G P P I W KN  P+             +  +   +V D  VYT  A N
Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G+      + V  P   N +  +     +EITV +  +  +       P PS+ W R+
Sbjct: 3418 RAGVDNKHYNLQVFAPP--NMDNSMGT---EEITVLKGSSTSMACITDGTPAPSMAWLRD 3472

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + +     +T +  G  ++L+    +   DSG Y C+ASN AG+ S        + KV 
Sbjct: 3473 GQPLGLDAHLTVSTHGMVLQLLKAETE---DSGKYTCIASNEAGEVSKHF-----ILKVL 3524

Query: 930  FVKHLQKSYETEEGKTVI-----LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXX 982
               H+  S E EE   ++     L C  S   + K  W  + + +   D  + +  G   
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL 3584

Query: 983  XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILE 1037
                      D G   C+      +     +V+  +P  I    + +D  V       LE
Sbjct: 3585 RISTAQVE--DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE 3642

Query: 1038 VEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095
             + ++    V+ W R+GE ++    +      G  R L I N  + D   Y+C+  + + 
Sbjct: 3643 CKSDAVPPPVITWLRNGERLQATP-RVRILSGG--RYLQINNADLGDTANYTCVASNIAG 3699

Query: 1096 -CTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151
              T E +  V +PP I    Q+  +   NK+T    + +G    R  W KDG+ +   NH
Sbjct: 3700 KTTREFILTVNVPPNIKGGPQSLVILL-NKSTVLECIAEGVPTPRITWRKDGAVLA-GNH 3757

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPEFI 1206
             + +I  +   L I    + D G Y C   N+  T    ++      PSI      P  +
Sbjct: 3758 ARYSIL-ENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI---APGPTNM 3813

Query: 1207 LVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             V  N    L  E   IP  +++  W K   ++   +       +   +L+I   + DD 
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSIN--WRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871

Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
              Y C + +     K  V++ V+ PP I D   ++ + + +   +       P P+  W 
Sbjct: 3872 ATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             N   I+            S ++ I   +   AG Y     N  G A   + + + + P 
Sbjct: 3932 KNG--IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
               +P+ L +  ++  +   E   T +  I +           E I+V    +    + +
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQ---------KEGINVNTSGRNHAVLPS 4040

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIEL 1501
                 S   R  A   + ++     T   K+  +  +Q P V  P LK      ++ I L
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGKI--KLNVQVPPVISPHLKEYVIAVDKPITL 4098

Query: 1502 TCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            +C   G+P P +TW++DG+ + ++ +    +                Y C+A N  G   
Sbjct: 4099 SCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSS 4158

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
            TS  + +   P I  S E     ++   + ++  V +GIP P + W K+   L N     
Sbjct: 4159 TSTKLTVHVPPRIR-STEGHYTVNE-NSQAILPCVADGIPTPAINWKKDNVLLAN--LLG 4214

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
              T E    + ++ +    S  YT  A+N AG  +  V+L V+  P+  E P
Sbjct: 4215 KYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELP 4266



 Score =  160 bits (389), Expect = 3e-37
 Identities = 222/1029 (21%), Positives = 397/1029 (38%), Gaps = 84/1029 (8%)

Query: 680  ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
            +++ ++  +    SV L I  V    EG Y  +AV+  G         +     EPP VI
Sbjct: 468  VTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS----EPPPVI 523

Query: 739  EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV 797
            +   ++ V  GE  +L+  ++      +TW +N++ V+ A P +     +    LK  K 
Sbjct: 524  QVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKF 583

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
             D G Y     +  G +  S  +TV+EP +    P     + Q  T   +  + ++   T
Sbjct: 584  NDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMP-----KNQSFTGGSE--VSIMCSAT 636

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              P P I W  N+  I  S       DG    L I N   + D+G Y C+ASNSAG    
Sbjct: 637  GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPK-DAGIYGCLASNSAGTDKQ 692

Query: 918  GARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHRE 974
             + +  I+  K+  V   Q       G   ++EC+TS       KW+    E+       
Sbjct: 693  NSTLRYIEAPKLMVV---QSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF-- 747

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEK 1031
            +I +              D G   C+  ++    T  + +   + P FI++  D  ++  
Sbjct: 748  LIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIG 807

Query: 1032 DVAILEVEINSETADVV-WER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
                L   +       + W R D   I  +        +     L+I N    D+G Y C
Sbjct: 808  SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867

Query: 1090 ILRDE--SCTAEVTVVE---LPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKD 1142
               ++     +E TV     + P I        V +G + T    L  G+ +   RW K+
Sbjct: 868  EAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKN 927

Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-----NSKCTAILTVEEPSIN 1197
             + +  + +I +  DG    L I    L D GEY+C        N+K T+++    P+I 
Sbjct: 928  SAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQ 984

Query: 1198 FTLRLPEFIL-VPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLII 1255
               ++   I  +P       +    +    V W KK  +I   + KF+  +D    +L +
Sbjct: 985  HGQQILSTIEGIPVTLPCKAS---GNPKPSVIWSKKGELISTSSAKFSAGAD---GSLYV 1038

Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER--------EYRIKRGSDVT 1306
                 ++  EY C   +     K KV++ V   P++   +R        E  +  G +VT
Sbjct: 1039 VSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVT 1098

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            L  + ++ P P   W   +++I         +   S S+ I +   +D+G+Y     N  
Sbjct: 1099 LPCEVKSLPPPIITWAKETQLISPFSPRHTFL--PSGSMKITETRTSDSGMYLCVATNIA 1156

Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426
            G+    + + +   P     P  L++    +    D P N   + +   V+ + +  +T 
Sbjct: 1157 GNVTQAVKLNVHVPPKIQRGPKHLKV---QVGQRVDIPCNAQGTPL--PVITWSKGGSTM 1211

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE- 1485
             +  ++         ++   +      Y     +I+   E TE    ++E     PTVE 
Sbjct: 1212 LVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE-TEITLHVQE----PPTVED 1266

Query: 1486 -KPLKNITTE---PNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXX 1538
             +P  N T +    N+ IE  C   G P+P + W  +G++L   +   +  E+       
Sbjct: 1267 LEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIA 1326

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                     Y C+A N+ G  E    + +   PVI    +       +     +   +EG
Sbjct: 1327 SVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEG 1386

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             P P ++WYK  + ++  +   I T     ++++       + +Y+ +A N AGTS    
Sbjct: 1387 TPSPIIMWYK--DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444

Query: 1659 TLKVYDKPS 1667
             + V   P+
Sbjct: 1445 NIDVLVPPT 1453



 Score =  151 bits (367), Expect = 2e-34
 Identities = 241/1167 (20%), Positives = 421/1167 (36%), Gaps = 118/1167 (10%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            GS+    C  +G P P + W R    +    D  +      +  L + +   ED+G +TC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTC 3506

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            +A N AG  S    L V  P   +GSE                 I  GIP      PK  
Sbjct: 3507 IASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIP-----APKMT 3561

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            ++ +G           +P+ D      G E                    VL+I+  +  
Sbjct: 3562 WMKDGR---------PLPQTDQVQTLGGGE--------------------VLRISTAQVE 3592

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGESVILSAQVVG 760
              G YT +A +  G+     ++++      PP +    EP + + V +   V L  +   
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHV----PPNIAGTDEP-RDITVLRNRQVTLECKSDA 3647

Query: 761  NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
             P P ITW +N + ++A P            +    + D   YT  A N  G      ++
Sbjct: 3648 VPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFIL 3707

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            TV  P      P   +     I + +   ++ +A     P P ITW ++  +++ +    
Sbjct: 3708 TVNVPPNIKGGPQSLV-----ILLNKSTVLECIAEGV--PTPRITWRKDGAVLAGNHARY 3760

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
               +   + +   +V    D+G Y C+A+N+AG       + + V           +   
Sbjct: 3761 SILENGFLHIQSAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIV 3817

Query: 941  EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
                T+  E       S  W  N   ++   ++   +               D    +C 
Sbjct: 3818 NVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECT 3877

Query: 1001 VKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEII 1056
            V +    +  T+ +  +  P    +  DF V +   A++    +      + W ++G  +
Sbjct: 3878 VTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRL 3937

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA--EVTV-VELPPEIITRL 1113
             P+ + Y     G I    I  T ++  G Y+C+ R+ + +A   VT+ V  PP I  + 
Sbjct: 3938 LPRGDGYRILSSGAIE---ILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQP 3994

Query: 1114 QNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS--NHIQLTIDGKKQKLKIYDCDL 1170
                V   N      E T      + W K+G  +  S  NH  L   G    L+I     
Sbjct: 3995 SELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG----LQISRAVR 4050

Query: 1171 DDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL- 1225
            +DAG Y C   N   TA+    L V+ P +  +  L E+++     D  +T+    + L 
Sbjct: 4051 EDAGTYMCVAQNPAGTALGKIKLNVQVPPV-ISPHLKEYVIA---VDKPITLSCEADGLP 4106

Query: 1226 --DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLK 1280
              D+TW+K  ++++E   +  L S     +L I      D   YTC+  +    S+T  K
Sbjct: 4107 PPDITWHKDGRAIVESIRQRVLSSG----SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC--KHTKPSI 1338
            +  V  PP+I   E  Y +   S   L       P P   W  ++ ++     K+T    
Sbjct: 4163 L-TVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTA--- 4218

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
                  L ++ V   D+G Y     N  G     +++T+   P+    P           
Sbjct: 4219 -EPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPG---------- 4267

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
               D   N G    +        +    W    NI        N  +       +   + 
Sbjct: 4268 ---DVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSG 4324

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEK-PLKNITTEP-NEDIELTCIFGGVPQPKVTWY 1516
              +  A  +  + K I    ++ P V K    +   EP   +  L C   G P P + W 
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWN 4384

Query: 1517 RDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            R G  ++ +    +                  Y C+A N+ G VE S  + +Q  P+IT+
Sbjct: 4385 RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL 4444

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
              E ++     G + ++     G P P + W + G+ +  D   N+ +      + I + 
Sbjct: 4445 --EPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS---LYIADA 4499

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++  +S++   A N  G+  V V + V
Sbjct: 4500 QKEDTSEFECVARNLMGSVLVRVPVIV 4526



 Score =  149 bits (362), Expect = 6e-34
 Identities = 233/1097 (21%), Positives = 389/1097 (35%), Gaps = 84/1097 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP  +  PK Q    GS++ + C     P+P IAW      IV      +   SD     
Sbjct: 611  PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT--SD----- 663

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I N      G Y  +A N  G       L+      E P+++     ++V  G+  
Sbjct: 664  GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRY----IEAPKLMVVQSELLVALGDIT 719

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            ++  +  G P P + W K +  ++            +  ++  +  D G YT  A N  G
Sbjct: 720  VMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG 779

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NN 870
             A     + V         PP+FI    +++++    + L   V   P P+I W R  N 
Sbjct: 780  RATGKITLDV-------GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
             I S   +++         L I N+ +  D G Y C A N  GK      VT+       
Sbjct: 833  PIFSRPFSVSSISQLRTGALFILNLWAS-DKGTYICEAENQFGKIQSETTVTVTGLVAPL 891

Query: 931  VKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            +          EG+ + L C     +     +W  N   +    +  +  +G        
Sbjct: 892  IGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQ 951

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046
                 +   +   V      T  VV   +P      Q     E     L  + + +    
Sbjct: 952  LQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPS 1011

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103
            V+W + GE+I     K+     G    LY+ +    + GEY C   + +  A+  V   V
Sbjct: 1012 VIWSKKGELISTSSAKFSAGADG---SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068

Query: 1104 ELPPEII---TRLQNQK-----VNKGNKATFEIEL-TKGDALVRWFKDGSEIQ-FSNHIQ 1153
             + P +      L   K     V  G + T   E+ +    ++ W K+   I  FS    
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHT 1128

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
                G    +KI +    D+G Y C      GN      L V  P      R P+ + V 
Sbjct: 1129 FLPSG---SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQ 1183

Query: 1210 ANTDAYLTVEIPDETLDV-TWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
                  +        L V TW K  S ++ D E      D    TL I + T  D   YT
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYT 1240

Query: 1268 CVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIK-----RGSDVTLLVDYQAFPQPNDEW 1321
            CV  +   T + ++ + V+ PP + D E  Y            +      +  P+P  +W
Sbjct: 1241 CVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKW 1300

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
            + N + +   +    SI      L I  V   D G Y     N  G  + + N+ +   P
Sbjct: 1301 LHNGRELTG-REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359

Query: 1382 SPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
                K  +  +    + +   + E E T +  I++Y      +  TE  +++ +   +  
Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWY---KDNVQVTESSTIQTVNNGK-- 1414

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNED 1498
            I  L   +      Y+   ++I+  S+  +Y+ +  +  +    +     N ++   N D
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQ--KYFNI--DVLVPPTIIGTNFPNEVSVVLNRD 1470

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFND 1555
            + L C   G P P + W++DGK L       E                    Y+C   N 
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             G+      + I   P I   N        +     +     G+P P + WYK+G  + +
Sbjct: 1531 AGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS 1590

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG---- 1671
              +      +K   + I   + S S+ YT   +N AGT+     + VY  P   EG    
Sbjct: 1591 SSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVY-VPPMIEGNLAT 1647

Query: 1672 PVIMREISRESVTIEWK 1688
            P+  + +   S+T+E K
Sbjct: 1648 PLNKQVVIAHSLTLECK 1664



 Score =  147 bits (356), Expect = 3e-33
 Identities = 238/1118 (21%), Positives = 422/1118 (37%), Gaps = 93/1118 (8%)

Query: 599  IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            I +  LSD G  E                D+ E  PP   + P    V  G   +L C +
Sbjct: 486  IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE--PPPVIQVPNNVTVTPGERAVLTCLI 543

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            ++  + ++ W     ++   E   +   +++      L++ +VK    G Y  +  +  G
Sbjct: 544  ISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-----LELKSVKFNDAGEYHCMVSSEGG 598

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             ++  + L +    +EPP+V    K+     G  V +     G P+P I W  N+  +  
Sbjct: 599  SSAASVFLTV----QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG 654

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI-AETSAVITVEEPTEENAEPPLFI 836
               +    +     +K    KD G+Y   A NS G   + S +  +E P     +  L +
Sbjct: 655  -SHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLV 713

Query: 837  NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
                +ITV E        + +  P P + W++ +  + PS  +  +     + L+     
Sbjct: 714  -ALGDITVME-------CKTSGIPPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQET 762

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSH 954
             ++D+GDY CVA N AG+++   ++T+DV               E G  V L C  Q   
Sbjct: 763  QDLDAGDYTCVAINEAGRAT--GKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP 820

Query: 955  TVSTKW--YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETST 1008
              + KW    N    S       I + R            D G   C  ++Q    ++ T
Sbjct: 821  EPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSET 880

Query: 1009 MLVVKETIPEFIRKLQDF-EVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDF 1065
             + V   +   I        V E     L   +   +   +  W ++  ++   +N Y  
Sbjct: 881  TVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML--LQNPYIT 938

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGN 1122
             +      L+I    + D GEY+C+  + + T   T   VV + P I    Q     +G 
Sbjct: 939  VRSD--GSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGI 996

Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
              T   + +      V W K G  I  S+       DG    L +     +++GEY C  
Sbjct: 997  PVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG---SLYVVSPGGEESGEYVCTA 1053

Query: 1179 --EVGNSKCTAILTV-EEPSI-----NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTW 1229
                G +K    LTV   P +       +   P  I V A  +  L  E+       +TW
Sbjct: 1054 TNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITW 1113

Query: 1230 YKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287
             K+  +I   + + T +      ++ I +    D   Y CV  +        V++ V  P
Sbjct: 1114 AKETQLISPFSPRHTFL---PSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP 1170

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLT 1346
            PKI    +  +++ G  V +  + Q  P P   W    S ++   +H    + +   +L+
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEH---HVSNPDGTLS 1227

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-----PPGKPNILEIDSSSINICW 1401
            I +   +DAGIY     N  G  + E+ + + + P+     PP      E  ++   I +
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEF 1286

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
              P        I ++   +E+   E  IS+     T   I ++    +  +   AVNE  
Sbjct: 1287 PCPAKGTPKPTIKWLHNGRELTGREPGISILE-DGTLLVIASVTPYDNGEYICVAVNE-- 1343

Query: 1461 ISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
               A  T   Y +    K+  P V   ++ + N++   N+   L C   G P P + WY+
Sbjct: 1344 ---AGTTERKYNL----KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396

Query: 1518 DGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            D  ++  +    T  N                Y C A N  G  +    + +   P I  
Sbjct: 1397 DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIG 1456

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
            +N   +    +  +  +   ++G P P++ W+K+G  L    + N+   ++  V+ +K  
Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            +R+   +Y    SN AG  + ++ L +Y  PS   G V
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNV 1553



 Score =  121 bits (291), Expect = 3e-25
 Identities = 205/965 (21%), Positives = 343/965 (35%), Gaps = 83/965 (8%)

Query: 632  IPPTFS--KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +PP  +   +P+   V     + LEC+  A+P P I WL  GE +     + +       
Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGG--- 3674

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L+I N        YT VA N  G+ +   +L +      PP +    +S+++   
Sbjct: 3675 ---RYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV----PPNIKGGPQSLVILLN 3727

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            +S +L     G P P ITW K+   +     +     +    ++   V D G Y   A N
Sbjct: 3728 KSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATN 3787

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
            + G       + V  P      P         +TV       L    T  P PSI W +N
Sbjct: 3788 AAGTDRRRIDLQVHVPPSIAPGPT-------NMTVIVNVQTTLACEATGIPKPSINWRKN 3840

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
              +++  +         +  LVI +   + D+  Y+C  +N AG       +T+ V    
Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVD-DTATYECTVTNGAGDDKRTVDLTVQVPPS- 3898

Query: 930  FVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
             +      +   +    ++ C  S       +  K  I  +   +  +            
Sbjct: 3899 -IADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILAT 3957

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETI--PEFIR-KLQDFEVKEKDVAILEVEINSETAD 1046
                 G   C+ ++   S    V   +  P  I+ +  +  V   +  +L  E     + 
Sbjct: 3958 QLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSP 4017

Query: 1047 -VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--- 1102
             + W+++G  +      +     G ++   I      D G Y C+ ++ + TA   +   
Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGGLQ---ISRAVREDAGTYMCVAQNPAGTALGKIKLN 4074

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQLTIDG 1158
            V++PP I   L+   +      T   E    D L    + W KDG  I  S   ++   G
Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCE---ADGLPPPDITWHKDGRAIVESIRQRVLSSG 4131

Query: 1159 KKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPE-FILVPANTD 1213
                L+I      DAG Y+C      G+S  +  LTV  P     +R  E    V  N+ 
Sbjct: 4132 S---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP---RIRSTEGHYTVNENSQ 4185

Query: 1214 AYLT-VEIPDETLDVTWYKKKSVIEDT-EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
            A L  V     T  + W K   ++ +   K+T         LI+     +D   YTCV  
Sbjct: 4186 AILPCVADGIPTPAINWKKDNVLLANLLGKYTA---EPYGELILENVVLEDSGFYTCVAN 4242

Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            +A       V + V   P   +   +  + +G  + L       P P   W  N+ II  
Sbjct: 4243 NAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPA 4302

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
              H   S++  S  L I++V   D+G Y    EN+ G       V + + P       + 
Sbjct: 4303 --HFD-SVNGHS-ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP-------VF 4351

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
            + D  S    W EP   G + I+   V+     T +W       +    I+ L   S   
Sbjct: 4352 KGDYPS---NWIEP--LGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS--- 4403

Query: 1451 FRAYAVNEVDISD-ASETTEYYKVIKET---KIQSPTV--EKPLKNITTEPNEDIELTCI 1504
               Y     D  D     T    V++ +    +QSP +   +P++ +     + I L C 
Sbjct: 4404 LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGK-IILNCQ 4462

Query: 1505 FGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
              G PQP +TW R G  +    +    +                ++C+A N  G V    
Sbjct: 4463 ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRV 4522

Query: 1564 VVGIQ 1568
             V +Q
Sbjct: 4523 PVIVQ 4527



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V   C   GYP+P+I W      I  S  ++M  D     TL I+   P+DAG + C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD----GTLFIKNAAPKDAGIYGC 681

Query: 584 VAKNAAGFASSTTEL-IVEAP 603
           +A N+AG     + L  +EAP
Sbjct: 682 LASNSAGTDKQNSTLRYIEAP 702



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 5/146 (3%)

Query: 514  EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
            E L   +  +G++V  EC+    P P ITW++   +I  S   ++  D      L I++ 
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ---MLHIKKA 3120

Query: 574  FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP 633
               D G + C A N AG       L V  P S  G E  V             D   GIP
Sbjct: 3121 EVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIP 3179

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVA 659
            P      K     E SD  LE R+++
Sbjct: 3180 PPTIAWLKNHKRIENSD-SLEVRILS 3204



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G     EC+  G P PQ+ WF+    ++PS        D  +  L I+E    DAG +TC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGDYTC 772

Query: 584 VAKNAAGFASSTTELIVEAP 603
           VA N AG A+    L V +P
Sbjct: 773 VAINEAGRATGKITLDVGSP 792



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 35/117 (29%), Positives = 50/117 (42%), Gaps = 10/117 (8%)

Query: 489  NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
            ++K  ++ V   PT +   ++   V K +P        V  +C   G P P ITW +   
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKP--------VALQCIANGIPNPSITWLKDDQ 1865

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
             +  +Q          V  L I +   EDAG +TCVA NAAG      +L V  P S
Sbjct: 1866 PVNTAQGNLKIQSSGRV--LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 7/95 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568
            P F E         G  ++  C+  G P P++TW     II P+     ++D  N  + L
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII-PA-----HFDSVNGHSEL 4313

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            VI  V  ED+GT+ C A+N+ GF  +   + V+ P
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 14/203 (6%)

Query: 469  VPAQYLMDENNYTQYLQKKLN--EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGST 526
            +P   + D   YT ++       EK   + V+  P  E     P+       K      +
Sbjct: 1605 IPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPL------NKQVVIAHS 1658

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            +  EC+  G P P +TW +    +K + + ++      +  +  +E+   D G + CVA 
Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVAT 1715

Query: 587  NAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
            + AG      E+ ++  P  + G E +               +    PPT       Q +
Sbjct: 1716 SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775

Query: 646  DE--GSDILLECRLVAIPEPDIA 666
            DE  G  ILL  R + I +  ++
Sbjct: 1776 DERDGFKILLNGRKLVIAQAQVS 1798



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 4/82 (4%)

Query: 522  PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            P G      C+V+G P P I W R+   I+ S   +   +     +L I     EDAG +
Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGN----GSLAIYGTVNEDAGDY 4417

Query: 582  TCVAKNAAGFASSTTELIVEAP 603
            TCVA N AG    +  L +++P
Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 38/185 (20%), Positives = 69/185 (37%), Gaps = 4/185 (2%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541
            PT  +   +++    E + L+C   G+P PK+TW  +   +     +             
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVS 4319

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C A N  G V+    V +++ PV    +        +G   ++   ++G P 
Sbjct: 4320 KEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFK-GDYPSNWIEPLGGNAILNCEVKGDPT 4378

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P + W + G  +E    + I      S + I       +  YT  A+N AG     ++L 
Sbjct: 4379 PTIQWNRKGVDIE--ISHRIRQLGNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435

Query: 1662 VYDKP 1666
            +   P
Sbjct: 4436 LQSPP 4440



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            + S     C  +G P P I W +   ++    +    Y  +    L++  V  ED+G +T
Sbjct: 4182 ENSQAILPCVADGIPTPAINWKKDNVLLA---NLLGKYTAEPYGELILENVVLEDSGFYT 4238

Query: 583  CVAKNAAGFASSTTELIV 600
            CVA NAAG  + T  L V
Sbjct: 4239 CVANNAAGEDTHTVSLTV 4256



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 5/106 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+   +    H    + +   C+  G P P ITW ++   +  S              L 
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQ 4044

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613
            I     EDAGT+ CVA+N AG A    +L V+ P  +S H  E  +
Sbjct: 4045 ISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVI 4090



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 4/78 (5%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +   CQ  G P+P ITW RQ   I  S D ++    +N  +L I +   ED   F C
Sbjct: 4454 GGKIILNCQATGEPQPTITWSRQGHSI--SWDDRVNVLSNN--SLYIADAQKEDTSEFEC 4509

Query: 584  VAKNAAGFASSTTELIVE 601
            VA+N  G       +IV+
Sbjct: 4510 VARNLMGSVLVRVPVIVQ 4527



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 519  KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            KH P   T    C   G P P I W +    + P  D         +  L  +      A
Sbjct: 3910 KHAPAVIT----CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL---NHA 3962

Query: 579  GTFTCVAKNAAGFASSTTELIVEAP 603
            G +TCVA+NAAG A     L V  P
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEP 3987


>UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole
            genome shotgun sequence; n=6; Fungi/Metazoa group|Rep:
            Chromosome undetermined SCAF9901, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 4648

 Score =  231 bits (564), Expect = 2e-58
 Identities = 172/616 (27%), Positives = 282/616 (45%), Gaps = 41/616 (6%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436
            DKPS PG+ +I+++ ++S+ I W  PE  G   ++ Y VE ++   + W   + + + + 
Sbjct: 2147 DKPSQPGEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCNKQRLKEK 2206

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
              ++  L   + Y FR  A NE  IS    T    K     + Q P++ K +  +TT+  
Sbjct: 2207 DFTVAGLAEATEYEFRVLAENETGISRPRRTATCIKTKLSVECQ-PSLRKEMDEVTTKLG 2265

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
            +   + C   G P P + WY  GK++    K   ++                   Y C A
Sbjct: 2266 QPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHSLSIITDQQEDEGEYTCKA 2325

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             ND GE ETS ++ ++  P     +  +K  +   +G    +  V  G P P+++W    
Sbjct: 2326 INDAGEAETSGILMLEAAPSFH-PDYPLKDTYCTGLGTTLRIHVVYIGRPQPKIMWLHGA 2384

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRS-HSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              LEN ++  I T E  + + IK ++R  H  KY I   N  G +     +++YDKP +P
Sbjct: 2385 KTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHNHFGRADTAFNVEIYDKPDRP 2444

Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE-PDNNRWIKVADVDRDVETYC- 1727
             GP+I+  + + SV I WKPP DDGG  +T Y +EKHE  +   W  V+       T C 
Sbjct: 2445 RGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEWELVSSSING--TSCR 2502

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L ++  Y FRV AQN  G SE LE + PI+IK+ L+ PS          I  +S  +
Sbjct: 2503 VPNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPS-PPLCPIVSGITKDSCVV 2561

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR-----IQKLSINTTYQFRIY 1840
            +W P   +GGS I  Y +E+K + K+ W           +     ++ L+    Y FR+ 
Sbjct: 2562 SWKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVFRVK 2621

Query: 1841 ARNEIGTSLPYTSDDKITIGKT----LTPPS---QPRNFVVSESTSRSVTLKWT-EPESN 1892
              N +G    Y S++ ++I       +  P+   + RN  V   ++ ++  K T +P+  
Sbjct: 2622 CEN-LGGQSDY-SEETLSIHPAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPK-- 2677

Query: 1893 GGSPITNYIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
               P+  ++   K +   GK   KI    G  H+  I  + E+D  +++I A N  G   
Sbjct: 2678 ---PVVKWLRRGKEIHSDGKK-IKIQEFKGGYHQLVISEVDEEDSTVYQIRATNQGGSIC 2733

Query: 1951 PTESQSVRLEKHATVP 1966
             T S  V +     +P
Sbjct: 2734 ATISLDVEVPAKIHLP 2749



 Score =  218 bits (533), Expect = 1e-54
 Identities = 172/692 (24%), Positives = 290/692 (41%), Gaps = 28/692 (4%)

Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
            VE +E P   +  D ++   ++ G  + L V     P P   W  +   +      +  +
Sbjct: 1157 VERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITWSKSETDLHNRGFIE--V 1214

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
             + S +L I KV   DAG Y +  EN+ G  +  + V + D P P     I E+   S+ 
Sbjct: 1215 TNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKVYDTPGPTRPIKIKELTKESVT 1274

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVN 1457
            I W+ P   G + +  Y++E +E     + +V +  +KT   I  L     Y FR    N
Sbjct: 1275 ISWEAPAIDGGAPVNNYIIERREASMRAYKTVTSKCSKTTFKIDGLMEGMLYYFRVLPEN 1334

Query: 1458 EVDISDASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
               I +  ET +   V    +   K++   V K    +  E  E    + + G + +   
Sbjct: 1335 IYGIGEPRETPDAILVCEVPLSPHKLEVIDVTKTTVTLGWEKPEHDGGSRLTGYIIEACK 1394

Query: 1514 TWYRDGKKLKTAKAT-YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---CVVGIQQ 1569
                   K+ T K T +E+                ++  A N  G  E       V +Q+
Sbjct: 1395 FGTDRWMKVATLKTTDFEH----TIEKLNESEQYLFRIRAINSRGASEPKELVTAVTVQE 1450

Query: 1570 KPVIT-ISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
            + V+  +    I QK      G    +   I G PPP   WY   N+++     +  +  
Sbjct: 1451 QRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYFRENRIKITDRIHFKSTG 1510

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            K S + I +     +  YT+E +N  G  S  + + +  KP +P+GP+   EI   +VT 
Sbjct: 1511 KFSKLVIHDTNIDDTGDYTLEVTNAVGLISEVIKVIILSKPDEPKGPLRFDEIDATTVTC 1570

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQ 1744
             W PP+ DGG  ++ + +E+ +     W+ V + V R   T+  + L E  EY+FR  A 
Sbjct: 1571 SWDPPIRDGGAPISGFVVEQRDAHRPGWVTVCESVSR--PTFKFENLIEGDEYVFRAAAT 1628

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
            N  G  E L+SE +  K+  +VP           I  + + + W P E++GG  +  Y +
Sbjct: 1629 NRYGTGEFLQSEIVTCKSLTNVPG-PPGRPTVFDISRDGMTVAWNPPEEDGGLEVSGYII 1687

Query: 1805 EIKQ-EGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            E K+    +W           R +   +     Y+ R+ A N  G S P           
Sbjct: 1688 ERKEVRSDRWVRANKNPITMTRYRSTELIEGLEYEHRVTALNAKGLSKPSLPSKPAVATD 1747

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
             + PP  P+N  ++++T  SV+L W+ P+  G + +  Y+IE + V   +W K  T    
Sbjct: 1748 PIDPPGCPQNPRITDTTKTSVSLAWSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSL 1807

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            + E+ + N+ + +E  FR+ A N  G   P E
Sbjct: 1808 ICEYTLTNMPQGEEFKFRVMACNAGGSGEPAE 1839



 Score =  198 bits (484), Expect = 1e-48
 Identities = 134/448 (29%), Positives = 200/448 (44%), Gaps = 20/448 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P P   W K+   L  +    I + E  S + IK  +RS S  Y +   N  G   
Sbjct: 1879 IRGKPQPTCKWSKDFGALSTNAM--IVSTEDVSELVIKGAERSDSGLYDLLLENRVGKKK 1936

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
             ++ +KV  +PS PEGP++  +I   SV + WK P+D+GG E+  Y +E+ E   N W  
Sbjct: 1937 AQIKVKVIGRPSAPEGPLVFDDIHANSVKVSWKVPIDNGGSEILGYILERREATRNAWYT 1996

Query: 1716 VADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXX 1773
            V    R  ET  + K L E  EY F+V A+N  GFS +L+SE P+V KT L  P      
Sbjct: 1997 VE--SRITETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHPVVPKTPLCSPEPPSTP 2054

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW-KXXXXXXXXXARIQKLSI 1831
                 I   SV + W   + +GGS +  Y VE +      W +           +  L+ 
Sbjct: 2055 PEIMDITKNSVALAWSRPKDDGGSAVTGYFVEYRIVSSDTWSRHETQITSTMFTLSGLTP 2114

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
            ++ YQFRI+A N IG S      D +T       PSQP    + + T+ SV ++W  PE 
Sbjct: 2115 DSEYQFRIFAVNSIGESEAGPVSDSVTCKDPFDKPSQPGEIDIVQVTNNSVAIRWQAPEC 2174

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            +GG  +  Y +E +     +W K         +  +  + E  E  FR+ AEN  G+S P
Sbjct: 2175 DGGKEVLGYWVECRKSIESTWKKCNKQRLKEKDFTVAGLAEATEYEFRVLAENETGISRP 2234

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
              + +  ++   +V   P+   E+     + V T  G P       ++   I  R V   
Sbjct: 2235 RRTATC-IKTKLSVECQPSLRKEM-----DEVTTKLGQP------AIMKCQIIGRPVPDI 2282

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
             W   GK  V + K+ +     NH+  I
Sbjct: 2283 KWYHAGKEIVESRKYQMSSDGRNHSLSI 2310



 Score =  188 bits (459), Expect = 1e-45
 Identities = 215/958 (22%), Positives = 398/958 (41%), Gaps = 69/958 (7%)

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            K   ++   +++  GE+S     ++   +  +E P +     L + I + A     L+V+
Sbjct: 1131 KYYFRVAGVNINGTGEFSEPCAAAE--PVERIETPDVELADDLKKTICLRAGGSLRLSVK 1188

Query: 1220 IPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
            +    +  +TW K ++ + +   F  +++    TLII K    D  +YT V  ++  K  
Sbjct: 1189 VTGRPVPAITWSKSETDLHN-RGFIEVTNTST-TLIIDKVHRYDAGKYTVVAENSAGKQE 1246

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK- 1335
              + V+V + P       R  +IK  +  ++ + ++A P  +    VN+ II++ + +  
Sbjct: 1247 ANILVKVYDTPGPT----RPIKIKELTKESVTISWEA-PAIDGGAPVNNYIIERREASMR 1301

Query: 1336 --PSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMN---VTILDKPSPPGKPN 1388
               ++ SK +  T K     +  +Y  R+  EN  G  +       + + + P  P K  
Sbjct: 1302 AYKTVTSKCSKTTFKIDGLMEGMLYYFRVLPENIYGIGEPRETPDAILVCEVPLSPHKLE 1361

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTN 1446
            ++++  +++ + W++PE+ G S +  Y++E  +  T  W+ V  +  T  + +I+ L  +
Sbjct: 1362 VIDVTKTTVTLGWEKPEHDGGSRLTGYIIEACKFGTDRWMKVATLKTTDFEHTIEKLNES 1421

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTC 1503
              Y FR  A+N    S+  E       ++E ++  P V+    P K I     + +EL  
Sbjct: 1422 EQYLFRIRAINSRGASEPKELVTAV-TVQEQRVM-PEVDFSAIPQKVINVLAGKTLELDL 1479

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VET 1561
               G P P  +WY    ++K     +                        +D G+  +E 
Sbjct: 1480 PIVGRPPPVCSWYFRENRIKITDRIHFKSTGKFSKLVIHDTN-------IDDTGDYTLEV 1532

Query: 1562 SCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPP--EVIWYKNGNKLENDK 1617
            +  VG+  +   VI +S  D  +     DE   T V     PP  +     +G  +E   
Sbjct: 1533 TNAVGLISEVIKVIILSKPDEPKGPLRFDEIDATTVTCSWDPPIRDGGAPISGFVVEQRD 1592

Query: 1618 EYN---ITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGT----SSVEVTLKVYDKPSK 1668
             +    +T  E  S    + + L       +   A+N  GT     S  VT K       
Sbjct: 1593 AHRPGWVTVCESVSRPTFKFENLIEGDEYVFRAAATNRYGTGEFLQSEIVTCKSLTNVPG 1652

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P G   + +ISR+ +T+ W PP +DGGLE++ Y IE+ E  ++RW++       +  Y  
Sbjct: 1653 PPGRPTVFDISRDGMTVAWNPPEEDGGLEVSGYIIERKEVRSDRWVRANKNPITMTRYRS 1712

Query: 1729 QKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
             +L E  EY  RV A N  G S+ +L S+P V    +D P               SV + 
Sbjct: 1713 TELIEGLEYEHRVTALNAKGLSKPSLPSKPAVATDPIDPPGCPQNPRITDT-TKTSVSLA 1771

Query: 1788 WFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNE 1844
            W P +  G + +  Y +E+++ G   W              +  +     ++FR+ A N 
Sbjct: 1772 WSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSLICEYTLTNMPQGEEFKFRVMACNA 1831

Query: 1845 IGTSLPYTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             G+  P      +T+ + L  P    +P+ +    +  +   ++ + P      P   + 
Sbjct: 1832 GGSGEPAEVPGTVTVTEMLESPDFDLEPK-YKDLYTVRQGGVVRLSVPIRGKPQPTCKWS 1890

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             +F  +   S   ++     V E  I+  +  D  ++ +  EN VG     +   +++ K
Sbjct: 1891 KDFGAL---STNAMIVSTEDVSELVIKGAERSDSGLYDLLLENRVG----KKKAQIKV-K 1942

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
                PS P  PL    + +N V  SW  P  +GG+ +LGY +  R+ T+  W  V +  +
Sbjct: 1943 VIGRPSAPEGPLVFDDIHANSVKVSWKVPIDNGGSEILGYILERREATRNAWYTV-ESRI 2001

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
               +  ++ L E   Y  ++ A N  G S  L+S+ P  V+P     + E P    E+
Sbjct: 2002 TETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHP--VVPKTPLCSPEPPSTPPEI 2057



 Score =  182 bits (444), Expect = 7e-44
 Identities = 150/658 (22%), Positives = 296/658 (44%), Gaps = 43/658 (6%)

Query: 1191 VEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245
            V+EP I  T  L E    L+ + + +  T+++P        +TW  ++  +++T++ ++ 
Sbjct: 433  VKEPHIEPTADLSEIDGQLIMSRSGSTFTIDVPISGRPAPKITWKLEEMRLKNTDRVSIK 492

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
                + ++ +++    D  +Y  +L +A  T    V+V     K         I   +  
Sbjct: 493  EAQNRTSISVKEAMRGDSGKYNLILENAAGTKTFVVDV-NVIGKPSPPTGPIEISSITAE 551

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDS--KSASLTIKKVENTDAGIYKL 1360
            + ++++   P+ +    + + I++K +    +   I+S  K  SL +  +       +++
Sbjct: 552  SCILNWHP-PEDDGGTDITNYIVEKRESGSTAWQLINSSVKRTSLFVSHLTKYMQYTFRV 610

Query: 1361 RLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
              ENN G +    + TI+ +     P PP +P++  I ++++ + W+EP + G S +  Y
Sbjct: 611  SAENNFGVSKATESETIVAEHPFTPPGPPTRPSVFNITANTMTLKWEEPYHDGGSKVTGY 670

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             +E +E +   W+    I   + +   ++L     Y+FR YA+N   +S ASE ++    
Sbjct: 671  WIEKKERNNILWVRENKIPCFECNYRAESLVEGLEYQFRVYAMNSAGLSKASEASK--GA 728

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKA 1527
            + +  +  PT  KP     T     ++ +        P V +  + K        +  K 
Sbjct: 729  VAQNPVDPPT--KPEVTNVTRTTVSLKWSAPLNDGGSPIVGYIIERKPYTLTGEGRWLKC 786

Query: 1528 TYENRXXXXXXXXXXXXXXXY--KCIAFNDHG--EVETSCVVGIQQK-----PVITISNE 1578
             Y N                Y  + IA N +    + +     +Q K     P   + ++
Sbjct: 787  NYTNVTDTFYTVTALGEGEPYEFRVIAKNANQVCSIPSESTGSVQCKTDFEPPKAQLDSK 846

Query: 1579 DIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
             + +   V  G + ++ A + G P P+  W K   +L+  ++Y++      ++  IK   
Sbjct: 847  LMSETVMVRAGSDLVLDAAVGGRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCD 906

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            R  + KY +   N +GT + EV++KV D P   EG + + +++ ES T+ WKPP++DGG 
Sbjct: 907  RDDTGKYILTVKNVSGTKTAEVSVKVLDTPGVCEGSITISKVTEESCTLSWKPPVEDGGD 966

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
            +++ Y +E+ + +   W+ V    +++    I +L +N EY+FRV   N  G    L+SE
Sbjct: 967  DVSHYIVERRDTNRLNWVIVHAECKELNCN-ITRLFKNTEYLFRVRGVNKYGPGVYLQSE 1025

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW 1813
            P+V +    VPS             +   I W   E +GGSP+I Y VE ++ +  +W
Sbjct: 1026 PMVARNTFTVPSPPGSPEIVAS-GKDFATIEWMKPESDGGSPLIHYLVERREKKSARW 1082



 Score =  181 bits (441), Expect = 2e-43
 Identities = 121/406 (29%), Positives = 191/406 (47%), Gaps = 16/406 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G  + +   I G P P++ W     +L+N    +I   +  + I +KE  R  S KY + 
Sbjct: 457  GSTFTIDVPISGRPAPKITWKLEEMRLKNTDRVSIKEAQNRTSISVKEAMRGDSGKYNLI 516

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
              N AGT +  V + V  KPS P GP+ +  I+ ES  + W PP DDGG ++T Y +EK 
Sbjct: 517  LENAAGTKTFVVDVNVIGKPSPPTGPIEISSITAESCILNWHPPEDDGGTDITNYIVEKR 576

Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
            E  +  W  +    +    + +  L +  +Y FRV A+N  G S+A ESE IV +     
Sbjct: 577  ESGSTAWQLINSSVKRTSLF-VSHLTKYMQYTFRVSAENNFGVSKATESETIVAEHPF-T 634

Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXX 1823
            P           I   ++ + W     +GGS +  Y +E K+     W  +         
Sbjct: 635  PPGPPTRPSVFNITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVRENKIPCFECN 694

Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883
             R + L     YQFR+YA N  G S    +         + PP++P    V+  T  +V+
Sbjct: 695  YRAESLVEGLEYQFRVYAMNSAGLSKASEASKGAVAQNPVDPPTKPE---VTNVTRTTVS 751

Query: 1884 LKWTEPESNGGSPITNYIIEFK--TVKGKS-WTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940
            LKW+ P ++GGSPI  YIIE K  T+ G+  W K      +   + +  + E +   FR+
Sbjct: 752  LKWSAPLNDGGSPIVGYIIERKPYTLTGEGRWLKCNYTNVTDTFYTVTALGEGEPYEFRV 811

Query: 1941 SAENTVGV-SLPTESQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
             A+N   V S+P+ES  SV+ +   T   PP A L+ +++   +++
Sbjct: 812  IAKNANQVCSIPSESTGSVQCK---TDFEPPKAQLDSKLMSETVMV 854



 Score =  174 bits (423), Expect = 3e-41
 Identities = 180/712 (25%), Positives = 301/712 (42%), Gaps = 53/712 (7%)

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
            R  +C      VE  P +   +       G  A  + ++       ++W+  G EI  S 
Sbjct: 2236 RTATCIKTKLSVECQPSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESR 2295

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLPEF 1205
              Q++ DG+   L I     +D GEY+C    + G ++ + IL +E  PS +    L + 
Sbjct: 2296 KYQMSSDGRNHSLSIITDQQEDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDYPLKDT 2355

Query: 1206 ILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
                  T   +  V I      + W      +E+TE  T+ +      LII+        
Sbjct: 2356 YCTGLGTTLRIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHG 2415

Query: 1265 -EYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
             +Y   L +   ++ T   VE+ + P +         + + S   +++ ++  P  +   
Sbjct: 2416 GKYRIRLHNHFGRADTAFNVEIYDKPDRPRGPIILDALLKNS---VIISWKP-PTDDGGC 2471

Query: 1322 IVNSKIIKKCKHTKPS---IDSKSASLTIKKVEN-TDAGIYKLRL--ENNCGHAD-VEMN 1374
            ++ + I++K +  +     + S S + T  +V N TD+  Y  R+  +N  G+++ +E+ 
Sbjct: 2472 MITNYIVEKHEDKEGGEWELVSSSINGTSCRVPNLTDSAGYFFRVYAQNRYGNSEPLELT 2531

Query: 1375 VTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-- 1427
              IL     +KPSPP  P +  I   S  + W  P + G S I  Y +E +  D  EW  
Sbjct: 2532 SPILIKSQLEKPSPPLCPIVSGITKDSCVVSWKPPISDGGSKIKSYCLEMKYKDKREWSE 2591

Query: 1428 ---ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
               ++   I +T  S++ L     Y FR    N    SD SE T         +I++P  
Sbjct: 2592 WTPVTTDEIKQTVFSVKCLTEGVEYVFRVKCENLGGQSDYSEETLSIHPAAAIEIRAPAF 2651

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGKKLKTA--KATYENRXXX 1535
            ++ L+N++ +   +  L C   G P+P V W R       DGKK+K    K  Y      
Sbjct: 2652 KEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQEFKGGYHQ---L 2708

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWL 1591
                        Y+  A N  G +  +  + ++    I +  +++K K  +    G+   
Sbjct: 2709 VISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIHLP-KNLKDKEAIPALRGEVVN 2767

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            +     G P P + W K  + ++++  Y  I T+  TS++    +++  +  Y + A N 
Sbjct: 2768 IKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYIVCAKNR 2827

Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
             G     V L V D P  P G V   +ISR+SVT+ W  P +DGG  +  Y IEK     
Sbjct: 2828 FGIDQQTVELDVADVPDPPRG-VKASDISRDSVTLNWVAPANDGGSRVISYIIEKCPTTA 2886

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761
             RW +VA   RD   Y +  L     Y FRVIA+N  G S   E S P++ K
Sbjct: 2887 ERWQRVAQ-SRDTH-YTVINLFGGTSYQFRVIAENKFGQSAPSETSGPVMTK 2936



 Score =  170 bits (414), Expect = 3e-40
 Identities = 206/918 (22%), Positives = 353/918 (38%), Gaps = 84/918 (9%)

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
            + E ++V A +D  L   +         W K    ++  EK+ L     +   +I+ C  
Sbjct: 848  MSETVMVRAGSDLVLDAAVGGRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCDR 907

Query: 1261 DDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
            DD  +Y   +  +    T ++ V+V++ P      E    I + ++ +  + ++   +  
Sbjct: 908  DDTGKYILTVKNVSGTKTAEVSVKVLDTPGVC---EGSITISKVTEESCTLSWKPPVEDG 964

Query: 1319 DE----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
             +    +IV  +   +        + K  +  I ++      ++++R  N  G      +
Sbjct: 965  GDDVSHYIVERRDTNRLNWVIVHAECKELNCNITRLFKNTEYLFRVRGVNKYGPGVYLQS 1024

Query: 1375 VTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE----------- 1418
              ++ +     PSPPG P I+        I W +PE+ G S +I+Y+VE           
Sbjct: 1025 EPMVARNTFTVPSPPGSPEIVASGKDFATIEWMKPESDGGSPLIHYLVERREKKSARWVK 1084

Query: 1419 ---------------YQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
                            QE  T EW     K +  T+  +  L   + Y FR   VN    
Sbjct: 1085 INRDGGAEVIGYILEMQEAGTEEWKKAHEKTLRGTEYVVIGLSAATKYYFRVAGVNINGT 1144

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
             + SE     + ++  +I++P VE      K I       + L+    G P P +TW + 
Sbjct: 1145 GEFSEPCAAAEPVE--RIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITWSKS 1202

Query: 1519 GKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
               L                           Y  +A N  G+ E + +V +   P  T  
Sbjct: 1203 ETDLHNRGFIEVTNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKVYDTPGPTRP 1262

Query: 1577 NEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
             + IK+  K  V   W   A+  G P    I  +    +   K   +T+K   +  +I  
Sbjct: 1263 IK-IKELTKESVTISWEAPAIDGGAPVNNYIIERREASMRAYK--TVTSKCSKTTFKIDG 1319

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            L       + +   N  G      T   + V + P  P    ++ ++++ +VT+ W+ P 
Sbjct: 1320 LMEGMLYYFRVLPENIYGIGEPRETPDAILVCEVPLSPHKLEVI-DVTKTTVTLGWEKPE 1378

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             DGG  LT Y IE  +   +RW+KVA +      + I+KLNE+ +Y+FR+ A N  G   
Sbjct: 1379 HDGGSRLTGYIIEACKFGTDRWMKVATLKTTDFEHTIEKLNESEQYLFRIRAINSRG--- 1435

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI----K 1807
               SEP  + TA+ V               + V             PI+     +     
Sbjct: 1436 --ASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYF 1493

Query: 1808 QEGKKWKXXXXXXXXXARIQKL-----SINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
            +E +             +  KL     +I+ T  + +   N +G     +   K+ I   
Sbjct: 1494 RENRIKITDRIHFKSTGKFSKLVIHDTNIDDTGDYTLEVTNAVGL---ISEVIKVIILSK 1550

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
               P  P  F   E  + +VT  W  P  +GG+PI+ +++E +      W   VTV  SV
Sbjct: 1551 PDEPKGPLRF--DEIDATTVTCSWDPPIRDGGAPISGFVVEQRDAHRPGW---VTVCESV 1605

Query: 1923 HEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
                   EN+ E DE +FR +A N  G     +S+ V  +    VP PP  P  +  +  
Sbjct: 1606 SRPTFKFENLIEGDEYVFRAAATNRYGTGEFLQSEIVTCKSLTNVPGPPGRP-TVFDISR 1664

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + +  +W  PE DGG  + GY I  ++V    W+   K  +   ++   +L E   Y  R
Sbjct: 1665 DGMTVAWNPPEEDGGLEVSGYIIERKEVRSDRWVRANKNPITMTRYRSTELIEGLEYEHR 1724

Query: 2041 IYARNEIGLSEPLESDEP 2058
            + A N  GLS+P    +P
Sbjct: 1725 VTALNAKGLSKPSLPSKP 1742



 Score =  136 bits (330), Expect = 5e-30
 Identities = 117/492 (23%), Positives = 201/492 (40%), Gaps = 25/492 (5%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-- 1435
            +D P  P  P I +   +S+++ W  P++ G++ +  Y++E Q++ TT WI         
Sbjct: 1749 IDPPGCPQNPRITDTTKTSVSLAWSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSLI 1808

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTE 1494
             + ++ N+     ++FR  A N     + +E      V +  +     +E   K++ T  
Sbjct: 1809 CEYTLTNMPQGEEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVR 1868

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIA 1552
                + L+    G PQP   W +D   L T     + E+                Y  + 
Sbjct: 1869 QGGVVRLSVPIRGKPQPTCKWSKDFGALSTNAMIVSTEDVSELVIKGAERSDSGLYDLLL 1928

Query: 1553 FNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-K 1608
             N  G+ +      V+G    P   +  +DI   + V   W V     G    E++ Y  
Sbjct: 1929 ENRVGKKKAQIKVKVIGRPSAPEGPLVFDDI-HANSVKVSWKVPIDNGG---SEILGYIL 1984

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-TSSVEVTLKVYDK-- 1665
               +   +  Y + ++   + + +K LK      + + A N+ G +SS++    V  K  
Sbjct: 1985 ERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHPVVPKTP 2044

Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
               P  P  P  + +I++ SV + W  P DDGG  +T Y +E     ++ W +  +    
Sbjct: 2045 LCSPEPPSTPPEIMDITKNSVALAWSRPKDDGGSAVTGYFVEYRIVSSDTWSR-HETQIT 2103

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
               + +  L  + EY FR+ A N +G SEA   S+ +  K   D PS          + N
Sbjct: 2104 STMFTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSVTCKDPFDKPS-QPGEIDIVQVTN 2162

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK--XXXXXXXXXARIQKLSINTTYQFR 1838
             SV I W   E +GG  ++ Y VE ++     WK             +  L+  T Y+FR
Sbjct: 2163 NSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCNKQRLKEKDFTVAGLAEATEYEFR 2222

Query: 1839 IYARNEIGTSLP 1850
            + A NE G S P
Sbjct: 2223 VLAENETGISRP 2234



 Score =  126 bits (305), Expect = 5e-27
 Identities = 93/335 (27%), Positives = 145/335 (43%), Gaps = 11/335 (3%)

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            DV    I+    +   ++ ++ +N VG  +A     I +K  +  PS          I  
Sbjct: 1907 DVSELVIKGAERSDSGLYDLLLENRVGKKKA----QIKVKV-IGRPSAPEGPLVFDDIHA 1961

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK-LSINTTYQFRI 1839
             SV ++W     NGGS I+ Y +E ++  +  W            + K L   T Y F++
Sbjct: 1962 NSVKVSWKVPIDNGGSEILGYILERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKV 2021

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPIT 1898
             A N  G S    S+  +     L  P  P     + + T  SV L W+ P+ +GGS +T
Sbjct: 2022 TAENSFGFSSSLKSEHPVVPKTPLCSPEPPSTPPEIMDITKNSVALAWSRPKDDGGSAVT 2081

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSV 1957
             Y +E++ V   +W++  T   S     +  +    E  FRI A N++G S     S SV
Sbjct: 2082 GYFVEYRIVSSDTWSRHETQITSTM-FTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSV 2140

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
              +     PS P   ++I  V +N V   W  PE DGG  +LGY +  R   ++ W +  
Sbjct: 2141 TCKDPFDKPSQP-GEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCN 2199

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            K  +    F +  L+E   Y  R+ A NE G+S P
Sbjct: 2200 KQRLKEKDFTVAGLAEATEYEFRVLAENETGISRP 2234



 Score =  124 bits (299), Expect = 3e-26
 Identities = 84/293 (28%), Positives = 128/293 (43%), Gaps = 9/293 (3%)

Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXX 1816
            +V    +  PS          I  ES  + W P E +GG+ I +Y VE ++ G   W+  
Sbjct: 527  VVDVNVIGKPSPPTGPIEISSITAESCILNWHPPEDDGGTDITNYIVEKRESGSTAWQLI 586

Query: 1817 XXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875
                   +  +  L+    Y FR+ A N  G S   T  + I      TPP  P    V 
Sbjct: 587  NSSVKRTSLFVSHLTKYMQYTFRVSAENNFGVSKA-TESETIVAEHPFTPPGPPTRPSVF 645

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
              T+ ++TLKW EP  +GGS +T Y IE K      W +   +      +  E++ E  E
Sbjct: 646  NITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVRENKIPCFECNYRAESLVEGLE 705

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
              FR+ A N+ G+S  +E+    + ++     PPT P E+  V    V   W  P  DGG
Sbjct: 706  YQFRVYAMNSAGLSKASEASKGAVAQNPV--DPPTKP-EVTNVTRTTVSLKWSAPLNDGG 762

Query: 1996 APLLGYNIAIRDVTKT---MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
            +P++GY I  +  T T    W++    +V    + +  L E   Y  R+ A+N
Sbjct: 763  SPIVGYIIERKPYTLTGEGRWLKCNYTNVTDTFYTVTALGEGEPYEFRVIAKN 815



 Score =  122 bits (295), Expect = 8e-26
 Identities = 69/255 (27%), Positives = 118/255 (46%), Gaps = 5/255 (1%)

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            +G P P ++W K+   L+  ++      E  + + IK +++ +  KYT+   N     S 
Sbjct: 105  KGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSF 164

Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
             + +     PSKP GP+ + E+  +S+ I W  P DDGG ++T Y +EK +   + W   
Sbjct: 165  HIHVITLGPPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTVEKRDTSQSNWKMA 224

Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
                +D + + +  L +  +Y F+V A+N  G SE L S+ ++ K     P         
Sbjct: 225  CSHVQDTQ-FKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFR-PPGPPGKPVV 282

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINT 1833
              + ++ + I W     +GG+PI  + VE K+     W+            RI  L    
Sbjct: 283  YNVTSDGMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGL 342

Query: 1834 TYQFRIYARNEIGTS 1848
             Y FR+YA+N+ G S
Sbjct: 343  EYSFRVYAQNDAGFS 357



 Score =  117 bits (281), Expect = 4e-24
 Identities = 93/377 (24%), Positives = 165/377 (43%), Gaps = 17/377 (4%)

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W  P  DGG  ++ Y IEK   D   W  +    R  E + ++KL E+ E  FRV A+N 
Sbjct: 1    WLKPSYDGGSIISDYIIEKKLKDEE-W-SLGGTSRQCE-FEVKKLKEHSEVFFRVAARNE 57

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXID---NESVYITWFPSEKNGGSPIIDYK 1803
             G  E +   PI +   +  P           +      +V+I   P +      ++  K
Sbjct: 58   KGQGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHNVHIE-LPYKGKPKPSMLWLK 116

Query: 1804 VEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
              +  +E ++ +           I+ +      ++ +   N++     +     IT+G  
Sbjct: 117  DNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIH--VITLG-- 172

Query: 1863 LTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
              PPS+P   + + E  + S+ + W EP  +GG  IT Y +E +     +W K+      
Sbjct: 173  --PPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTVEKRDTSQSNW-KMACSHVQ 229

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
              +  + N+ +  +  F++ AEN  GVS P  SQ V  +     P PP  P+ +  V S+
Sbjct: 230  DTQFKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPV-VYNVTSD 288

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
             +   W  P +DGG P+ G+++  +++   MW +V  + +   ++ I  L E   Y  R+
Sbjct: 289  GMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFRV 348

Query: 2042 YARNEIGLSEPLESDEP 2058
            YA+N+ G S   +  +P
Sbjct: 349  YAQNDAGFSRIGDESKP 365



 Score =  114 bits (274), Expect = 3e-23
 Identities = 67/222 (30%), Positives = 109/222 (49%), Gaps = 7/222 (3%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            ++ +   N  GT   +  D  + IGK  +PP+ P    +S  T+ S  L W  PE +GG+
Sbjct: 512  KYNLILENAAGTKT-FVVDVNV-IGKP-SPPTGP--IEISSITAESCILNWHPPEDDGGT 566

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             ITNYI+E +     +W +++          + ++ +  +  FR+SAEN  GVS  TES+
Sbjct: 567  DITNYIVEKRESGSTAW-QLINSSVKRTSLFVSHLTKYMQYTFRVSAENNFGVSKATESE 625

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
            ++  E   T P PPT P  +  + +N +   W  P  DGG+ + GY I  ++    +W+ 
Sbjct: 626  TIVAEHPFTPPGPPTRP-SVFNITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVR 684

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              K+      +    L E   Y  R+YA N  GLS+  E+ +
Sbjct: 685  ENKIPCFECNYRAESLVEGLEYQFRVYAMNSAGLSKASEASK 726



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 17/319 (5%)

Query: 523  DGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            +G +V+F C +E Y    ++TW+     ++ S  +++ Y+D  VA + I ++   D GT+
Sbjct: 3199 EGDSVKFVCNIENYDSTTEVTWYCGVRQLEASDKYEIAYED-GVAVITINKITRADDGTY 3257

Query: 582  TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
             C   N  G  S+  EL V   +  +    T             A +L+  PP F+    
Sbjct: 3258 RCKIVNEYGEDSAYAELFVTG-VRLYRDYFTSRVVKKTKRRVDTARMLQK-PPEFTLPLV 3315

Query: 642  AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYCSVLKITNV 700
             +    G D+     +   P+P + W   G++++P  ++      SD  +Y   L I N+
Sbjct: 3316 NRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFISDKGLY--QLIIHNL 3373

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-----LKSMIVRQGESVILS 755
                +  Y+VVA NR GE S    L +    K     + P     L ++  ++G+ V   
Sbjct: 3374 DAEDDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFE 3433

Query: 756  AQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             +V G+  PT+ W K+  P+    ++    +G  + I  ++    +D GVY + A NS G
Sbjct: 3434 IRVSGH--PTLRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAG 3491

Query: 813  IAETSAVITVEEPTEENAE 831
             A   A + VE  T    E
Sbjct: 3492 SASCQATLKVERVTHVKKE 3510



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 135/620 (21%), Positives = 232/620 (37%), Gaps = 35/620 (5%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            I+DA E  E   ++      S   + PLK+   T     + +  ++ G PQPK+ W    
Sbjct: 2326 INDAGEA-ETSGILMLEAAPSFHPDYPLKDTYCTGLGTTLRIHVVYIGRPQPKIMWLHGA 2384

Query: 1520 KKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
            K L+     T + T                   Y+    N  G  +T+  V I  KP   
Sbjct: 2385 KTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHNHFGRADTAFNVEIYDKPDRP 2444

Query: 1575 ISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
                  D   K+ V   W       G      I  K+ +K   + E   ++   TS  R+
Sbjct: 2445 RGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEWELVSSSINGTSC-RV 2503

Query: 1633 KELKRSHSSKYTIEASNTAGTSS-VEVTLKVY-----DKPSKPEGPVIMREISRESVTIE 1686
              L  S    + + A N  G S  +E+T  +      +KPS P  P++   I+++S  + 
Sbjct: 2504 PNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPSPPLCPIVSG-ITKDSCVVS 2562

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV---ETYCIQKLNENCEYMFRVIA 1743
            WKPP+ DGG ++  Y +E    D   W +   V  D      + ++ L E  EY+FRV  
Sbjct: 2563 WKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVFRVKC 2622

Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            +N  G S+ + E+  I    A+++ +                             P++ +
Sbjct: 2623 ENLGGQSDYSEETLSIHPAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKW 2682

Query: 1803 K---VEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
                 EI  +GKK K            I ++    +  ++I A N+ G+     S D   
Sbjct: 2683 LRRGKEIHSDGKKIKIQEFKGGYHQLVISEVDEEDSTVYQIRATNQGGSICATISLDVEV 2742

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
              K   P +      +       V +K   P      P+  +      +      +++  
Sbjct: 2743 PAKIHLPKNLKDKEAIPALRGEVVNIKI--PFVGKPDPVITWQKGQDLIDSNGHYQVIVT 2800

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
                       +++KD   + + A+N  G+    + Q+V L+  A VP PP   ++   +
Sbjct: 2801 RSFTSLVFPSGVEKKDAGFYIVCAKNRFGI----DQQTVELDV-ADVPDPPRG-VKASDI 2854

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
              + V  +W  P  DGG+ ++ Y I     T   W  V +       + + +L    +Y 
Sbjct: 2855 SRDSVTLNWVAPANDGGSRVISYIIEKCPTTAERWQRVAQ--SRDTHYTVINLFGGTSYQ 2912

Query: 2039 IRIYARNEIGLSEPLESDEP 2058
             R+ A N+ G S P E+  P
Sbjct: 2913 FRVIAENKFGQSAPSETSGP 2932



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 48/167 (28%), Positives = 83/167 (49%), Gaps = 2/167 (1%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            I+ G +V + + Y+  P+P+  W+ ++  +K+ +  +       A+L IK V   + G Y
Sbjct: 92   IRLGHNVHIELPYKGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKY 151

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             L L+N        ++V  L  PS P G   + E+ + SI I WDEP + G   I  Y V
Sbjct: 152  TLTLDNKVNRRSFHIHVITLGPPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTV 211

Query: 1418 EYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            E ++   + W ++  ++  TQ  + NL     Y+F+ YA N   +S+
Sbjct: 212  EKRDTSQSNWKMACSHVQDTQFKVLNLIKGVQYQFKVYAENRYGVSE 258



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 56/204 (27%), Positives = 100/204 (49%), Gaps = 10/204 (4%)

Query: 1866 PSQPRNFVVSESTSR-SVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923
            P +PR  ++ ++  + SV + W  P  +GG  ITNYI+E  +  +G  W ++V+   +  
Sbjct: 2441 PDRPRGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEW-ELVSSSINGT 2499

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNI 1982
               + N+ +     FR+ A+N  G S P E  S + ++     PSPP  P+ +  +  + 
Sbjct: 2500 SCRVPNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPSPPLCPI-VSGITKDS 2558

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK---FNIRDLSENHTYMI 2039
             + SW  P  DGG+ +  Y + ++   K  W E   V  + +K   F+++ L+E   Y+ 
Sbjct: 2559 CVVSWKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVF 2618

Query: 2040 RIYARNEIGLSEPLESDEPFKVIP 2063
            R+   N  G S+   S+E   + P
Sbjct: 2619 RVKCENLGGQSD--YSEETLSIHP 2640



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 8/202 (3%)

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTK 781
            +K K   +  P + + +  +  + G+  I+  Q++G P P I W    K +   +     
Sbjct: 2241 IKTKLSVECQPSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMS 2300

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
            SDG  HS++I+  ++ +DEG YT KA N  G AETS ++ +E     + + PL       
Sbjct: 2301 SDGRNHSLSIITDQQ-EDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDYPLKDTYCTG 2359

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +      T+++       P P I W    + +  +E IT         L+I NV   +  
Sbjct: 2360 LGT----TLRIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHG 2415

Query: 902  GDYKCVASNSAGKSSHGARVTI 923
            G Y+    N  G++     V I
Sbjct: 2416 GKYRIRLHNHFGRADTAFNVEI 2437



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 124/610 (20%), Positives = 234/610 (38%), Gaps = 45/610 (7%)

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            ++  + S  + E+S    VE+  E    P   +N+   +TV     ++    V  +P PS
Sbjct: 4045 SVSVKESTTLVESSTA--VEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPS 4102

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ITW  +  +I+ S          +  L I++V +  D G Y  +  N+AGK      +TI
Sbjct: 4103 ITWIHDGAVITSSAHHHIFSTQYDSHLEISSV-TMADEGSYMVLVENAAGKQEAHFTLTI 4161

Query: 924  -----DVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVSTKWYHN-KKEISGMDHREI 975
                   + VT  + +    ET   K+   +   Q   +   K     K  +SG    ++
Sbjct: 4162 FKAESTEQVVTPTRVMSPETETPFSKSPDPVRSPQRVRSPDPKSPQRVKSPVSGKTTPKL 4221

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035
                                  + +  D E  + + V     E         + E     
Sbjct: 4222 PGLKSPPPSDKAPITSSVKSPKRVMSPDPEKKSSISVGPN-KEITSSHSQLTIAEGQSLT 4280

Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC------ 1089
            L   I   ++ + W  +G+ +    ++Y +   G  + L I + S H +G+ +C      
Sbjct: 4281 LSARIPGASS-IRWLLNGKELS-NSDQYRYGVSGANQNLTIMSVSHHHQGKITCEAETAE 4338

Query: 1090 -ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI 1146
             ++R +  T   T     P  +++ ++Q V +G    F  E++ G+    + W KD   I
Sbjct: 4339 GLVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVS-GEPFPDIEWLKDNMPI 4397

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA-------ILTVEEPSIN 1197
              S++I+L+       L+I++    D+G+Y+ +  N   +C+A        LT E   + 
Sbjct: 4398 NVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMM 4457

Query: 1198 FTLRLPEFILVPANTDAYLTVEI-----PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
              L+        +   ++   E+     P      +       + D    + +S +   +
Sbjct: 4458 MVLQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSES 4517

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF----PPKIVDYEREYRIKRGSDVTLL 1308
            ++    T   Q +   V   A++++ L+    E     PPKI    +   ++ G  +TL 
Sbjct: 4518 MV--SMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLS 4575

Query: 1309 VDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
              +   P P  +WI    +I  + K  +    +  ++L I  V+  DAG Y L L N  G
Sbjct: 4576 GAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTLMLTNEFG 4635

Query: 1368 HADVEMNVTI 1377
                 +NV I
Sbjct: 4636 SDTATVNVHI 4645



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 81/381 (21%), Positives = 149/381 (39%), Gaps = 18/381 (4%)

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            W +P   G S I  Y++E +++   EW       + +  ++ LK +S   FR  A NE  
Sbjct: 1    WLKPSYDGGSIISDYIIE-KKLKDEEWSLGGTSRQCEFEVKKLKEHSEVFFRVAARNEKG 59

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
              +         +      ++   E P   ++     ++ +   + G P+P + W +D  
Sbjct: 60   QGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHNVHIELPYKGKPKPSMLWLKDNL 119

Query: 1521 KLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---CVVGIQQKPVI 1573
             LK ++       EN+               Y     N             +G   KPV 
Sbjct: 120  PLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIHVITLGPPSKPVG 179

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRI 1632
             I  ++++    +   W       G    ++  Y    +  +   + +     + +  ++
Sbjct: 180  PIRLDEVR-ADSIMISWDEPNDDGG---GDITCYTVEKRDTSQSNWKMACSHVQDTQFKV 235

Query: 1633 KELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
              L +    ++ + A N  G S    S  V  K   +P  P G  ++  ++ + +TI+W+
Sbjct: 236  LNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPVVYNVTSDGMTIQWE 295

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
             P+ DGG  +  + +EK E ++  W KV  +      Y I  L E  EY FRV AQN  G
Sbjct: 296  KPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFRVYAQNDAG 355

Query: 1749 FSE-ALESEPIVIKTALDVPS 1768
            FS    ES+P +  + +  P+
Sbjct: 356  FSRIGDESKPTMAVSPVASPN 376



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 66/297 (22%), Positives = 119/297 (40%), Gaps = 15/297 (5%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  +P++Q V EG ++   C +   P PDI WL         +N+ + + S++ + CS
Sbjct: 4357 PHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWL--------KDNMPINVSSNIKLSCS 4408

Query: 694  V----LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L+I NV     G YTV A N  G+ S    L + T  +EP +++  L++  +   
Sbjct: 4409 QNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMVLQTETISTA 4468

Query: 750  ESVILS---AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
             S+  S    +V G   P      +             ++    ++    V       +K
Sbjct: 4469 GSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSESMVSMTSSSQMK 4528

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
              +    AE S+ +       +   PP   +  Q + V+E  T+ L    + +P P + W
Sbjct: 4529 KMSVFSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQW 4588

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              + + I   E   +  +  +I  +  +   E D+G Y  + +N  G  +    V I
Sbjct: 4589 IHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTLMLTNEFGSDTATVNVHI 4645



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%)

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDE 800
            + + +G+S+ LSA++ G    +I W  N K +           G   ++TI+       +
Sbjct: 4271 LTIAEGQSLTLSARIPG--ASSIRWLLNGKELSNSDQYRYGVSGANQNLTIMSVSH-HHQ 4327

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            G  T +AE +EG+       TV   T  ++  P F+++ +   V E   +K    V+  P
Sbjct: 4328 GKITCEAETAEGLVRCQFDTTV---TTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEP 4384

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---- 916
             P I W ++N  I+ S  I  +     ++L I NV +  DSG Y   A N  G+ S    
Sbjct: 4385 FPDIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAA-DSGKYTVKAKNEFGQCSATSS 4443

Query: 917  -HGARVT---------IDVEKVTFVKHLQKSYETEE--GKTVILECQTSH-TVSTKWYHN 963
             H   +T         +  E ++    +QKS+   E  GK   +   +S  + + K+  +
Sbjct: 4444 LHVHTLTQEPMEMMMVLQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLID 4503

Query: 964  KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL 1023
            K+  S M    ++ E               V          +T +  +   + P+     
Sbjct: 4504 KRSESSMS--AMMSESMVSMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGSPPKIKSLS 4561

Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
            Q+  V+E     L    + + A +V W   G+ I  ++ +Y  E    I  L I      
Sbjct: 4562 QNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEG 4621

Query: 1083 DEGEYSCILRDE--SCTAEVTV 1102
            D G Y+ +L +E  S TA V V
Sbjct: 4622 DAGAYTLMLTNEFGSDTATVNV 4643



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 79/326 (24%), Positives = 132/326 (40%), Gaps = 33/326 (10%)

Query: 498  FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
            F+   +   S AP F+ + R ++  +G  V+F C+V G P P I W +    I  S + +
Sbjct: 4345 FDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWLKDNMPINVSSNIK 4404

Query: 558  MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
            +     NV  L I  V   D+G +T  AKN  G  S+T+ L V     +    M V    
Sbjct: 4405 LSC-SQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMVLQTE 4463

Query: 618  XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
                         G  P    K    + D  S             P  A  F  ++   +
Sbjct: 4464 TISTAGSIQKSFSG--PEVHGKAFPMHADSSS-------------PSAAAKFLIDK-RSE 4507

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQ 736
             ++S  +   M    S+   + +KK        V  + E  +SL  +  ++K G   PP+
Sbjct: 4508 SSMSAMMSESM---VSMTSSSQMKKMS------VFSHAEASSSLQTLSSELKMG--SPPK 4556

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITI-LK 793
            +    ++M V +G+++ LS    G+P P + W  + +  P +    + +  T   T+ + 
Sbjct: 4557 IKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRIS 4616

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAV 819
              K  D G YTL   N  G ++T+ V
Sbjct: 4617 AVKEGDAGAYTLMLTNEFG-SDTATV 4641



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 27/292 (9%)

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286
            W K    ++++E+        K TL+I+   ++++ +YT  L +  +     + V+    
Sbjct: 114  WLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIHVITLGP 173

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            P K V   R   ++  S   +++ +    +PND+   +       K      + K A   
Sbjct: 174  PSKPVGPIRLDEVRADS---IMISWD---EPNDDGGGDITCYTVEKRDTSQSNWKMACSH 227

Query: 1347 IK----KVENTDAGI---YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDS 1394
            ++    KV N   G+   +K+  EN  G ++  ++  ++ K     P PPGKP +  + S
Sbjct: 228  VQDTQFKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPVVYNVTS 287

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452
              + I W++P   G + I  + VE +E+++  W  V    I +T+  I  L     Y FR
Sbjct: 288  DGMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFR 347

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIEL 1501
             YA N+   S   +  E    +  + + SP +E   +  + +T +  ++I L
Sbjct: 348  VYAQNDAGFSRIGD--ESKPTMAVSPVASPNIEFGPEYFEGLTVKAGDNIRL 397



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 10/203 (4%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P+  K+        G   +++C+++  P PDI W   G+EIV      ++ +   H    
Sbjct: 2251 PSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHS--- 2307

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESV 752
             L I   ++  EG YT  A+N  GEA    +L ++      P    PLK +     G ++
Sbjct: 2308 -LSIITDQQEDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDY--PLKDTYCTGLGTTL 2364

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLKAEN 809
             +    +G P+P I W    K ++     +   T   T L  K V+     G Y ++  N
Sbjct: 2365 RIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHN 2424

Query: 810  SEGIAETSAVITVEEPTEENAEP 832
              G A+T+  + + +  +    P
Sbjct: 2425 HFGRADTAFNVEIYDKPDRPRGP 2447



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 56/204 (27%), Positives = 91/204 (44%), Gaps = 10/204 (4%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F ++ +   V   S+  L C++   P+P + WL +G+EI  D    + I+     Y  
Sbjct: 2649 PAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGK-KIKIQEFKGGY-H 2706

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752
             L I+ V +     Y + A N+ G     I L ++   K   P+ ++  +++   +GE V
Sbjct: 2707 QLVISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIHLPKNLKDKEAIPALRGEVV 2766

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKV--KDEGVYTLKAEN 809
             +    VG P P ITW K    + +        T S T ++ P  V  KD G Y + A+N
Sbjct: 2767 NIKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYIVCAKN 2826

Query: 810  SEGIAETSAVITVEEPTEENAEPP 833
              GI +     TVE    +  +PP
Sbjct: 2827 RFGIDQQ----TVELDVADVPDPP 2846



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 11/209 (5%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            + EG  + L  R+       I WL  G+E+   +     +          L I +V    
Sbjct: 4273 IAEGQSLTLSARIPGASS--IRWLLNGKELSNSDQYRYGVSGANQN----LTIMSVSHHH 4326

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            +G  T  A   EG         + T     P  +   +S  V +G++V  + +V G P P
Sbjct: 4327 QGKITCEAETAEGLVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFP 4386

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITV 822
             I W K+N P+          + ++  L+   V   D G YT+KA+N  G    ++ + V
Sbjct: 4387 DIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHV 4446

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIK 851
               T+E  E  + +   Q  T+   G+I+
Sbjct: 4447 HTLTQEPMEMMMVL---QTETISTAGSIQ 4472



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 20/165 (12%)

Query: 1047 VVWERDGEIIKP--KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100
            V W + G+ + P     KY F     + +L I N    D+ EYS + R    ++SC A +
Sbjct: 3339 VTWHKSGQKLIPGLDDKKYTFISDKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKARL 3398

Query: 1101 TVVELP--------PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152
            TVV  P        P     L N +  +G    FEI ++ G   +RW KDG+ + F   I
Sbjct: 3399 TVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFEIRVS-GHPTLRWEKDGAPLAFGPSI 3457

Query: 1153 QLTIDGKKQ-KLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192
            ++  +G     L + D   +D+G Y    +   G++ C A L VE
Sbjct: 3458 EVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAGSASCQATLKVE 3502



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 72/325 (22%), Positives = 114/325 (35%), Gaps = 14/325 (4%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G+P     KP +  V+ G  +   C +   P P I W+  G  I    +  +        
Sbjct: 4069 GVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVITSSAHHHIF----STQ 4124

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            Y S L+I++V    EG+Y V+  N  G+      L I   E    QV+ P + M      
Sbjct: 4125 YDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAE-STEQVVTPTRVMSPETET 4183

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
                S   V +P+  +       P +     S   T  +  LK     D+   T   ++ 
Sbjct: 4184 PFSKSPDPVRSPQ-RVRSPDPKSPQRVKSPVSGKTTPKLPGLKSPPPSDKAPITSSVKSP 4242

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            + +               N E     +   ++T+ E  ++ L AR+      SI W  N 
Sbjct: 4243 KRVMSPDPEKKSSISVGPNKE---ITSSHSQLTIAEGQSLTLSARIP--GASSIRWLLNG 4297

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKV 928
            + +S S+       G N  L I +V S    G   C A  + G  +      VT      
Sbjct: 4298 KELSNSDQYRYGVSGANQNLTIMSV-SHHHQGKITCEAETAEGLVRCQFDTTVTTSHSAA 4356

Query: 929  TFVKHLQKSYETEEGKTVILECQTS 953
                   +S    EG+ V   C+ S
Sbjct: 4357 PHFLSQPRSQNVVEGQNVKFTCEVS 4381



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 57/211 (27%), Positives = 100/211 (47%), Gaps = 17/211 (8%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NKPVKALPTK-----SDGD 785
            ++PP+   PL +     GE +     +  +P P +TW K+  K +  L  K     SD  
Sbjct: 3305 QKPPEFTLPLVNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFISDKG 3364

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFINRFQEI 842
             + + I+     +D+  Y++ A N  G     A +TV  P  + A+    P+F      +
Sbjct: 3365 LYQL-IIHNLDAEDDAEYSVVARNRYGEDSCKARLTV-VPRPKPADLTLRPMFKRLLANL 3422

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG-ENIELVITNVDSEIDS 901
              KE   ++   RV+ +  P++ W ++   ++   +I    +G +   L + +V  E DS
Sbjct: 3423 ECKEGQDVRFEIRVSGH--PTLRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPE-DS 3479

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            G Y+  A+NSAG +S   + T+ VE+VT VK
Sbjct: 3480 GVYRVTATNSAGSAS--CQATLKVERVTHVK 3508



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 4/128 (3%)

Query: 476  DENNYTQYLQKKLNEKIDK--LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            D+  Y+   + +  E   K  L V  +P   + ++ P+F   L      +G  V+FE +V
Sbjct: 3377 DDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFEIRV 3436

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G+P   + W +  A +      ++ ++  +   L +R+V PED+G +   A N+AG AS
Sbjct: 3437 SGHPT--LRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAGSAS 3494

Query: 594  STTELIVE 601
                L VE
Sbjct: 3495 CQATLKVE 3502



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 66/291 (22%), Positives = 119/291 (40%), Gaps = 35/291 (12%)

Query: 723  IVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT-ITWCKNNKPVKALPTK 781
            +V K+K    E   V   ++  +V++G+SV     +      T +TW    + ++A    
Sbjct: 3174 LVAKVKIAPYENGPVGGLIRHAVVKEGDSVKFVCNIENYDSTTEVTWYCGVRQLEASDKY 3233

Query: 782  SDGDTHSITILKPKKVK--DEGVYTLKAENSEG----IAE-------------TSAVITV 822
                   + ++   K+   D+G Y  K  N  G     AE             TS V+  
Sbjct: 3234 EIAYEDGVAVITINKITRADDGTYRCKIVNEYGEDSAYAELFVTGVRLYRDYFTSRVVKK 3293

Query: 823  EEPTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-- 876
             +   + A    +PP F       T      ++    +T +P P +TW+++ + + P   
Sbjct: 3294 TKRRVDTARMLQKPPEFTLPLVNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLD 3353

Query: 877  -ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKV 928
             +  T   D    +L+I N+D+E D  +Y  VA N  G+ S  AR+T+       D+   
Sbjct: 3354 DKKYTFISDKGLYQLIIHNLDAE-DDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLR 3412

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
               K L  + E +EG+ V  E + S   + +W  +   ++     E++ EG
Sbjct: 3413 PMFKRLLANLECKEGQDVRFEIRVSGHPTLRWEKDGAPLAFGPSIEVVHEG 3463



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  PR    S+ +  SVTL W  P ++GGS + +YIIE      + W + V      H +
Sbjct: 2843 PDPPRGVKASDISRDSVTLNWVAPANDGGSRVISYIIEKCPTTAERWQR-VAQSRDTH-Y 2900

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             + N+       FR+ AEN  G S P+E+    + K
Sbjct: 2901 TVINLFGGTSYQFRVIAENKFGQSAPSETSGPVMTK 2936



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 60/327 (18%), Positives = 122/327 (37%), Gaps = 18/327 (5%)

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            L+  IP  +  + W      + +++++        + L I   +   Q + TC    A+ 
Sbjct: 4281 LSARIPGAS-SIRWLLNGKELSNSDQYRYGVSGANQNLTIMSVSHHHQGKITCEAETAEG 4339

Query: 1276 TTKLKVEVV-----EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
              + + +          P  +   R   +  G +V    +    P P+ EW+ ++  I  
Sbjct: 4340 LVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWLKDNMPINV 4399

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN-I 1389
              + K S       L I  V   D+G Y ++ +N  G      ++ +      P +   +
Sbjct: 4400 SSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMV 4459

Query: 1390 LEIDS----SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--L 1443
            L+ ++     SI   +  PE  G +  ++             I  ++ +     +    +
Sbjct: 4460 LQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSESMV 4519

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELT 1502
               SS + +  +V     S A  ++    +  E K+ SP   K L +N+  E  + + L+
Sbjct: 4520 SMTSSSQMKKMSV----FSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLS 4575

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY 1529
              F G P P V W   G+++ T +  Y
Sbjct: 4576 GAFSGDPAPLVQWIHSGQRIPTEEKRY 4602



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G     +CQ+ G P P I W+     I  S+ +QM  D  N +  +I +   ED G +TC
Sbjct: 2265 GQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHSLSIITDQ-QEDEGEYTC 2323

Query: 584  VAKNAAGFASSTTELIVEAPLSDH 607
             A N AG A ++  L++EA  S H
Sbjct: 2324 KAINDAGEAETSGILMLEAAPSFH 2347



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 3/115 (2%)

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMI-VRQGESVILSAQVVGNPRPTIT 767
            V +N  GE S P          E P V   + LK  I +R G S+ LS +V G P P IT
Sbjct: 1139 VNINGTGEFSEPCAAAEPVERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAIT 1198

Query: 768  WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            W K+   +         +T +  I+      D G YT+ AENS G  E + ++ V
Sbjct: 1199 WSKSETDLHNRGFIEVTNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKV 1253



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 11/183 (6%)

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIKPKKNK 1062
            +ET   +VV E+I          E   K +  L++ E    +  +      E+  PK   
Sbjct: 3819 RETGARVVVSESIESEYLTAFTSEYIPKPIKKLQMPEPTKSSLSLAKAAKTEVTLPK--- 3875

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122
             DF  R   RK  +R      E ++      ES T     ++L P I  R+++ +V+ G+
Sbjct: 3876 IDFASRYAERKQALRTERKSAEKKF------ESMTQPPFSLDLTPRITVRMRSHRVSYGS 3929

Query: 1123 KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              +F + +  K +  + WF +G E+  S+   ++       L+I +C  DD+G Y     
Sbjct: 3930 STSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVLTLQINNCVADDSGAYRVICK 3989

Query: 1182 NSK 1184
            N+K
Sbjct: 3990 NAK 3992



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 3/125 (2%)

Query: 478  NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM--APIFVEKLRPKHTPDGSTVQFECQVEG 535
            + Y +  Q    E+      FE  T    S+   P    ++R      GS+  F   V+ 
Sbjct: 3880 SRYAERKQALRTERKSAEKKFESMTQPPFSLDLTPRITVRMRSHRVSYGSSTSFTLNVQA 3939

Query: 536  YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
             P P+ITWF     +  S  + M  +   V TL I     +D+G +  + KNA G  S  
Sbjct: 3940 KPEPEITWFHNGKELHQSSKYHM-SNISGVLTLQINNCVADDSGAYRVICKNAKGETSDY 3998

Query: 596  TELIV 600
              L V
Sbjct: 3999 ATLDV 4003



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 1/108 (0%)

Query: 501  PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559
            P +  +  AP F E+LR       S     C++ G P+P + W R+   I    +  ++ 
Sbjct: 2640 PAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQ 2699

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
                    LVI EV  ED+  +   A N  G   +T  L VE P   H
Sbjct: 2700 EFKGGYHQLVISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIH 2747



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 41/188 (21%), Positives = 73/188 (38%), Gaps = 8/188 (4%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGD 785
            E   P   E L++M V+   +  L  ++ G P+P + W +  K +     K    +  G 
Sbjct: 2645 EIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQEFKGG 2704

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
             H + I +  + +D  VY ++A N  G    +  + VE P + +   P  +   + I   
Sbjct: 2705 YHQLVISEVDE-EDSTVYQIRATNQGGSICATISLDVEVPAKIHL--PKNLKDKEAIPAL 2761

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
                + +       P P ITW +  ++I  +             LV  +   + D+G Y 
Sbjct: 2762 RGEVVNIKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYI 2821

Query: 906  CVASNSAG 913
              A N  G
Sbjct: 2822 VCAKNRFG 2829



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 5/157 (3%)

Query: 575  PEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX--XXXADILEGI 632
            P  A  F    ++ +  ++  +E +V    S    +M+V              +++  G 
Sbjct: 4494 PSAAAKFLIDKRSESSMSAMMSESMVSMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGS 4553

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP      +   V+EG  + L       P P + W+  G+ I P E     +E+   +  
Sbjct: 4554 PPKIKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRI-PTEEKRYRVENSTDI-- 4610

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
            S L+I+ VK+   G YT++  N  G  +  + + I++
Sbjct: 4611 STLRISAVKEGDAGAYTLMLTNEFGSDTATVNVHIRS 4647



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 5/117 (4%)

Query: 809  NSEGIAETSAVITVEEPTE--ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            N  G  E S      EP E  E  +  L  +  + I ++  G+++L  +VT  PVP+ITW
Sbjct: 1140 NINGTGEFSEPCAAAEPVERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITW 1199

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             ++   +     I       +  L+I  V    D+G Y  VA NSAGK      V +
Sbjct: 1200 SKSETDLHNRGFI--EVTNTSTTLIIDKV-HRYDAGKYTVVAENSAGKQEANILVKV 1253



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 58/252 (23%), Positives = 95/252 (37%), Gaps = 38/252 (15%)

Query: 480  YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539
            +T  + KK   ++D   + +KP        P F   L  +    G  ++F   +  +P P
Sbjct: 3286 FTSRVVKKTKRRVDTARMLQKP--------PEFTLPLVNRTAYIGEDLRFGVTITVHPDP 3337

Query: 540  QITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
            ++TW +    + P  D + Y    D  +  L+I  +  ED   ++ VA+N  G  S    
Sbjct: 3338 RVTWHKSGQKLIPGLDDKKYTFISDKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKAR 3397

Query: 598  L-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            L +V  P                      AD+   + P F +        EG D+  E R
Sbjct: 3398 LTVVPRP--------------------KPADLT--LRPMFKRLLANLECKEGQDVRFEIR 3435

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +     P + W   G  +    +I V  E    +   +L + +V     G Y V A N  
Sbjct: 3436 VSG--HPTLRWEKDGAPLAFGPSIEVVHEG---LDYFILHVRDVLPEDSGVYRVTATNSA 3490

Query: 717  GEASLPIVLKIK 728
            G AS    LK++
Sbjct: 3491 GSASCQATLKVE 3502



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARV 856
            ++ ++ ++A NS G +E   ++T     E+   P +  +   +  I V    T++L   +
Sbjct: 1422 EQYLFRIRAINSRGASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPI 1481

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVI--TNVDSEIDSGDYKCVASNSAGK 914
               P P  +WY     I  ++ I     G+  +LVI  TN+D   D+GDY    +N+ G 
Sbjct: 1482 VGRPPPVCSWYFRENRIKITDRIHFKSTGKFSKLVIHDTNID---DTGDYTLEVTNAVGL 1538

Query: 915  SSHGARVTI 923
             S   +V I
Sbjct: 1539 ISEVIKVII 1547



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 44/155 (28%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 697  ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGES 751
            +TN+ + +E  + V+A N  G    A +P  + +    + P   +EP  K +  VRQG  
Sbjct: 1813 LTNMPQGEEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVRQGGV 1872

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            V LS  + G P+PT  W K+   +         +  S  ++K  +  D G+Y L  EN  
Sbjct: 1873 VRLSVPIRGKPQPTCKWSKDFGALSTNAMIVSTEDVSELVIKGAERSDSGLYDLLLENRV 1932

Query: 812  GIAETSAVITVEEPTEENA-EPPLFINRFQEITVK 845
            G  +  A I V+     +A E PL  +     +VK
Sbjct: 1933 G--KKKAQIKVKVIGRPSAPEGPLVFDDIHANSVK 1965



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  V+F C V+G P P ITW    A+I  S    ++    + + L I  V   D G++  
Sbjct: 4086 GDLVRFSCDVDGDPAPSITWIHDGAVITSSAHHHIFSTQYD-SHLEISSVTMADEGSYMV 4144

Query: 584  VAKNAAG 590
            + +NAAG
Sbjct: 4145 LVENAAG 4151



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 53/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)

Query: 736  QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL----PTKSDGDTHSITI 791
            +V E  +++    G  V++S  +        T     KP+K L    PTKS     S+++
Sbjct: 3809 EVEEKAQTLKRETGARVVVSESIESEYLTAFTSEYIPKPIKKLQMPEPTKS-----SLSL 3863

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN-----AEPPLFINRFQEITVKE 846
             K  K +   V   K + +   AE    +  E  + E       +PP  ++    ITV+ 
Sbjct: 3864 AKAAKTE---VTLPKIDFASRYAERKQALRTERKSAEKKFESMTQPPFSLDLTPRITVRM 3920

Query: 847  KG-------TIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSE 898
            +        +      V   P P ITW+ N  E+   S+    N  G  + L I N  ++
Sbjct: 3921 RSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGV-LTLQINNCVAD 3979

Query: 899  IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
             DSG Y+ +  N+ G++S  A + +   +      L+K  E
Sbjct: 3980 -DSGAYRVICKNAKGETSDYATLDVAGTEYAAFSSLRKDEE 4019



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE---NDKEYNITT 1623
            +Q+ P  T+    + +   +G++      I   P P V W+K+G KL    +DK+Y   +
Sbjct: 3304 LQKPPEFTLPL--VNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFIS 3361

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
             +    + I  L     ++Y++ A N  G  S +  L V  +P KP    +     R   
Sbjct: 3362 DKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKARLTVVPRP-KPADLTLRPMFKRLLA 3420

Query: 1684 TIEWKPPLD 1692
             +E K   D
Sbjct: 3421 NLECKEGQD 3429



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 6/120 (5%)

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIE--PLKSMIVRQGES 751
           ++  +K+  E  + V A N +G+     +  IK  +    P   +   P  ++ +R G +
Sbjct: 38  EVKKLKEHSEVFFRVAARNEKGQGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHN 97

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809
           V +     G P+P++ W K+N P+K         T +   L  K V+  +EG YTL  +N
Sbjct: 98  VHIELPYKGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDN 157



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 17/156 (10%)

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIE----PLKSMIVRQGE 750
            I  + + ++  + + A+N  G AS P  +V  +   E+     ++    P K + V  G+
Sbjct: 1415 IEKLNESEQYLFRIRAINSRG-ASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGK 1473

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            ++ L   +VG P P  +W      +K    +  KS G   S  ++    + D G YTL+ 
Sbjct: 1474 TLELDLPIVGRPPPVCSWYFRENRIKITDRIHFKSTG-KFSKLVIHDTNIDDTGDYTLEV 1532

Query: 808  ENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEI 842
             N+ G I+E   VI + +P E     PL   RF EI
Sbjct: 1533 TNAVGLISEVIKVIILSKPDEPKG--PL---RFDEI 1563



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V  E   +G P+P + W +    +K S+  + +   +N ATL+I+ V  E+ G +T 
Sbjct: 95  GHNVHIELPYKGKPKPSMLWLKDNLPLKESEQIR-FKKTENKATLMIKNVRKENEGKYTL 153

Query: 584 VAKNAAGFASSTTELIVEAPLS 605
              N     S    +I   P S
Sbjct: 154 TLDNKVNRRSFHIHVITLGPPS 175



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)

Query: 1582 QKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            + H+V  G     T  ++  P PE+ W+ NG +L    +Y+++       ++I       
Sbjct: 3921 RSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVLTLQINNCVADD 3980

Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
            S  Y +   N  G +S   TL V
Sbjct: 3981 SGAYRVICKNAKGETSDYATLDV 4003



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/113 (23%), Positives = 42/113 (37%)

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            L+++ +  +   E    P KIV+      +  G  V    D    P P+  WI +  +I 
Sbjct: 4054 LVESSTAVEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVIT 4113

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
               H         + L I  V   D G Y + +EN  G  +    +TI    S
Sbjct: 4114 SSAHHHIFSTQYDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAES 4166



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 30/135 (22%), Positives = 57/135 (42%), Gaps = 3/135 (2%)

Query: 1559 VETSCVVG-IQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            VE+S  V  + ++P +   I N+       +GD    +  ++G P P + W  +G  + +
Sbjct: 4055 VESSTAVEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVITS 4114

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
               ++I + +  S + I  +  +    Y +   N AG      TL ++   S  +     
Sbjct: 4115 SAHHHIFSTQYDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAESTEQVVTPT 4174

Query: 1676 REISRESVTIEWKPP 1690
            R +S E+ T   K P
Sbjct: 4175 RVMSPETETPFSKSP 4189



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 6/90 (6%)

Query: 1100 VTVVE--LPPEI-ITRLQNQKVNKGNKATFEIELT---KGDALVRWFKDGSEIQFSNHIQ 1153
            VTV E  + PE+  + +  + +N     T E++L    +   +  W+   + I+ ++ I 
Sbjct: 1446 VTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYFRENRIKITDRIH 1505

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
                GK  KL I+D ++DD G+Y+ EV N+
Sbjct: 1506 FKSTGKFSKLVIHDTNIDDTGDYTLEVTNA 1535



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            G    ++    G P P V W  +G ++  + K Y +      S +RI  +K   +  YT+
Sbjct: 4569 GQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTL 4628

Query: 1646 EASNTAGTSSVEVTLKV 1662
              +N  G+ +  V + +
Sbjct: 4629 MLTNEFGSDTATVNVHI 4645



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GST   +  + G P P+ITW  +   +K + D     +  N  ++ ++E    D+G +  
Sbjct: 457 GSTFTIDVPISGRPAPKITWKLEEMRLK-NTDRVSIKEAQNRTSISVKEAMRGDSGKYNL 515

Query: 584 VAKNAAG 590
           + +NAAG
Sbjct: 516 ILENAAG 522



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 22/84 (26%), Positives = 38/84 (45%)

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            ++  P+I    R +R+  GS  +  ++ QA P+P   W  N K + +      S  S   
Sbjct: 3910 LDLTPRITVRMRSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVL 3969

Query: 1344 SLTIKKVENTDAGIYKLRLENNCG 1367
            +L I      D+G Y++  +N  G
Sbjct: 3970 TLQINNCVADDSGAYRVICKNAKG 3993



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 5/127 (3%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEI-TVKEKGTIKLVARV 856
            +E  + + A N+ G  E + V      TE    P   +  +++++ TV++ G ++L   +
Sbjct: 1820 EEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVRQGGVVRLSVPI 1879

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
               P P+  W ++   +S +  I    D    ELVI   +   DSG Y  +  N  GK  
Sbjct: 1880 RGKPQPTCKWSKDFGALSTNAMIVSTEDVS--ELVIKGAERS-DSGLYDLLLENRVGKKK 1936

Query: 917  HGARVTI 923
               +V +
Sbjct: 1937 AQIKVKV 1943



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 4/89 (4%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P  + + ++  V  GS       + A PEP+I W   G+E+       ++  S +   
Sbjct: 3912 LTPRITVRMRSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGV--- 3968

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEAS 720
               L+I N      G Y V+  N +GE S
Sbjct: 3969 -LTLQINNCVADDSGAYRVICKNAKGETS 3996



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 18/77 (23%), Positives = 34/77 (44%)

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            T  + G P P++ W K+   +       ++  +    + I  +  + S KYT++A N  G
Sbjct: 4377 TCEVSGEPFPDIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFG 4436

Query: 1653 TSSVEVTLKVYDKPSKP 1669
              S   +L V+    +P
Sbjct: 4437 QCSATSSLHVHTLTQEP 4453



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 11/125 (8%)

Query: 708 YTVVAVNREGEASLPIV----LKIKTGEKEPP--QVIEPLKS--MIVRQGESVILSAQVV 759
           + V+A N     S+P      ++ KT + EPP  Q+   L S  ++VR G  ++L A V 
Sbjct: 809 FRVIAKNANQVCSIPSESTGSVQCKT-DFEPPKAQLDSKLMSETVMVRAGSDLVLDAAVG 867

Query: 760 GNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
           G P P   W K N+ +            T ++ ++K     D G Y L  +N  G     
Sbjct: 868 GRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCDRDDTGKYILTVKNVSGTKTAE 927

Query: 818 AVITV 822
             + V
Sbjct: 928 VSVKV 932



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 3/67 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G +++   +V G P P ITW +    +      ++    +   TL+I +V   DAG +T 
Sbjct: 1180 GGSLRLSVKVTGRPVPAITWSKSETDLHNRGFIEV---TNTSTTLIIDKVHRYDAGKYTV 1236

Query: 584  VAKNAAG 590
            VA+N+AG
Sbjct: 1237 VAENSAG 1243



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 109/504 (21%), Positives = 197/504 (39%), Gaps = 57/504 (11%)

Query: 634  PTFSKKPKAQ---YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            P F  +PK +    V +G  + L   +   P+P   W      +    N  +    D+  
Sbjct: 1853 PDFDLEPKYKDLYTVRQGGVVRLSVPIRGKPQPTCKWSKDFGAL--STNAMIVSTEDV-- 1908

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI--KTGEKEPPQVIEPLKSMIVRQ 748
              S L I   ++   G Y ++  NR G+    I +K+  +    E P V + + +  V+ 
Sbjct: 1909 --SELVIKGAERSDSGLYDLLLENRVGKKKAQIKVKVIGRPSAPEGPLVFDDIHANSVKV 1966

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
               V +     G+        +      A  T     T +  ++K  K   E  + + AE
Sbjct: 1967 SWKVPIDNG--GSEILGYILERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKVTAE 2024

Query: 809  NSEGIAET--SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSIT 865
            NS G + +  S    V +    + EPP       +IT   K ++ L  +R   +   ++T
Sbjct: 2025 NSFGFSSSLKSEHPVVPKTPLCSPEPPSTPPEIMDIT---KNSVALAWSRPKDDGGSAVT 2081

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG-DYKCVASNSAGKSSHGA---RV 921
             Y     I  S+T +++ + +    + T      DS   ++  A NS G+S  G     V
Sbjct: 2082 GYFVEYRIVSSDTWSRH-ETQITSTMFTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSV 2140

Query: 922  T-------------IDVEKVT--FVKHLQKSYETEEGKTVI---LECQTSHTVSTKWYH- 962
            T             ID+ +VT   V    ++ E + GK V+   +EC+ S  + + W   
Sbjct: 2141 TCKDPFDKPSQPGEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKS--IESTWKKC 2198

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEF 1019
            NK+ +   D   +                 + G    I + + T+T +  K ++   P  
Sbjct: 2199 NKQRLKEKDFT-VAGLAEATEYEFRVLAENETG----ISRPRRTATCIKTKLSVECQPSL 2253

Query: 1020 IRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIR 1077
             +++ +   K    AI++ +I      D+ W   G EI++ +K +   + R H   L I 
Sbjct: 2254 RKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNH--SLSII 2311

Query: 1078 NTSVHDEGEYSCILRDESCTAEVT 1101
                 DEGEY+C   +++  AE +
Sbjct: 2312 TDQQEDEGEYTCKAINDAGEAETS 2335


>UniRef50_Q14324 Cluster: Myosin-binding protein C, fast-type; n=24;
            Euteleostomi|Rep: Myosin-binding protein C, fast-type -
            Homo sapiens (Human)
          Length = 1142

 Score =  231 bits (564), Expect = 2e-58
 Identities = 187/768 (24%), Positives = 335/768 (43%), Gaps = 41/768 (5%)

Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            F +KL   ++V   +   L VEI+     + W ++G+ IKP  +KY FE  G  R L I 
Sbjct: 258  FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPS-SKYVFENVGKKRILTIN 316

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
              ++ D+  Y   ++DE C  E+ V E P  I+T L++Q+V  G++    +E+++  A V
Sbjct: 317  KCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV 376

Query: 1138 RWFKDGSEI----QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
             W KDG E+     F    +   DGK+  L   D   +D G Y       +C A L VEE
Sbjct: 377  MWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEE 436

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
              +     + + + V A+  A    E+ DE +   WYK    +  +++ T+    +   L
Sbjct: 437  KQLEVLQDIAD-LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKL 495

Query: 1254 IIRKCTEDDQCEYTCV-------LLDAK-STTKLKVEVV--EFPPKI-VD-----YEREY 1297
            +I     +D+ +YT V        L AK +  ++KVE V  + PPKI +D      E   
Sbjct: 496  VIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 555

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAG 1356
             +  G+ + L V     P P   W+   ++    +  T+       +S  I+  +  D G
Sbjct: 556  VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 615

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             Y +++ N  G     + + ++D P PP    I  +      + W+ P   G   +  Y+
Sbjct: 616  RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 675

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSS--YRFRAYAVNEVDISDASETTEYYKVI 1474
            VE ++  +  W+ +     T+T+ ++ K      Y  R +AVN + +S  S  T+ +  I
Sbjct: 676  VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 735

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG-KKLKTAKATYENRX 1533
              T      + + + + TT            GG+    V +  +G ++   A      R 
Sbjct: 736  APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 795

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV------GIQQKPVITISNEDIKQKH--K 1585
                          ++ +  N  G  E + +        I + P I +    ++Q +  K
Sbjct: 796  GFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRH-LRQTYIRK 854

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            VG++  +    +G P P+V+W K G  L+  +  ++ T +  +V  +++  RS S +Y +
Sbjct: 855  VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYEL 913

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
                     +  + ++V +K   P   V+++E+   +  +EW+ P DDG  E+  Y ++K
Sbjct: 914  SVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 972

Query: 1706 HEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEA 1752
             +     W  V   +R+  T C +  L    EY FRV  +N  G S++
Sbjct: 973  ADKKTMEWFNV--YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS 1018



 Score =  142 bits (345), Expect = 7e-32
 Identities = 152/647 (23%), Positives = 269/647 (41%), Gaps = 47/647 (7%)

Query: 920  RVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
            +  ++V+K   F K L  +Y+ + G  + L  + S   ++ KW+ N +EI          
Sbjct: 247  KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037
             G+            D    +  VKD++  T L VKE     +  L+D +V   D   + 
Sbjct: 307  VGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366

Query: 1038 VEINSETADVVWERDG-EIIKPK--KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            VE++ E A V+W +DG E+ +    K +Y F+K G    L   +    D G Y  I    
Sbjct: 367  VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
             C AE+ V E   E++  + +  V    +A F+ E++      +W+K+G E++ S  I +
Sbjct: 427  QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486

Query: 1155 TIDGKKQKLKIYDCDLDDAGEY------------SCEVG--NSKCTAILTVEEPSINFTL 1200
            +  G+  KL I D   +D G+Y            S ++     K   +   E P I+   
Sbjct: 487  SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDC 546

Query: 1201 ---RLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISD-VKKRTLII 1255
                    I+V A     L V I  E   V TW K   V   TE  T I   V   + +I
Sbjct: 547  SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVI 606

Query: 1256 RKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQ 1312
                 +D+  YT  + +   +    + ++VV+ P    D     RI   G D  +LV ++
Sbjct: 607  ESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP----DPPEAVRITSVGEDWAILV-WE 661

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT---DAGIYKLRL--ENNCG 1367
                   + +    + +K K ++  +       T    E+T   +  +Y++R+   N  G
Sbjct: 662  PPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG 721

Query: 1368 HADVEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
             +   MN       +P  +P  L   ++  ++  + W  P   G   I  Y+VEY    +
Sbjct: 722  VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS 781

Query: 1425 TEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDISDASETTEYYKVIKETKI 1479
             EW+  + + + +   +++NL T +   FR   VN     + +  ++     ++ +  KI
Sbjct: 782  EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKI 841

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
            + P   +  +    +  E + L   F G P+P+V W + G  L T++
Sbjct: 842  RLPRHLR--QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 886



 Score =  116 bits (278), Expect = 9e-24
 Identities = 107/479 (22%), Positives = 192/479 (40%), Gaps = 35/479 (7%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            G++  +   I G PPP   W K        +    I  +   S   I+  +R    +YTI
Sbjct: 560  GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 619

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            + +N  G     + L+V D P  PE  V +  +  +   + W+PP+ DGG  +T Y +E+
Sbjct: 620  KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 678

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTAL 1764
             +  + RW+K+        TY   K+ E   Y  RV A N +G S+ ++ ++P +     
Sbjct: 679  KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----P 734

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXX 1823
              P+          + + +  + W P  + G   I  Y VE   EG ++W          
Sbjct: 735  IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 794

Query: 1824 A--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                ++ L       FR+   N  G + P T    +TI +   PP       + ++  R 
Sbjct: 795  CGFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRK 854

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKD-EIIFR 1939
            V           G  + N ++ F   +GK   ++V T GG+  +    +++  D + +F 
Sbjct: 855  V-----------GEQL-NLVVPF---QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF 899

Query: 1940 I-------SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992
            +       S E  + V +     +  +       + P   + ++ V     +  W  P+ 
Sbjct: 900  VRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKD 959

Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            DG + ++GY +   D     W  V + + +T    + DL   + Y  R+Y  N  GLS+
Sbjct: 960  DGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVSDLIVGNEYYFRVYTENICGLSD 1017



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 103/432 (23%), Positives = 166/432 (38%), Gaps = 43/432 (9%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA-GTSSVEVT---LK 1661
            WYKNG ++   K   I+   +   + I +++      YT      A G+ S ++    +K
Sbjct: 471  WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIK 530

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            V   P K E P I  + S +  T E    +  G       +I    P    W+K  +V  
Sbjct: 531  VEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 587

Query: 1722 ------------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
                        D  ++ I+      E  + +   NPVG     E    +    +DVP  
Sbjct: 588  TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPD- 641

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ- 1827
                     +  +   + W P   +GG P+  Y VE K++G ++W             + 
Sbjct: 642  PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 701

Query: 1828 -KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
             K+     Y+ R++A N IG S P  +         + P S+P + +V + T  + TLKW
Sbjct: 702  TKMIEGILYEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKW 758

Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946
              P   G   I  Y++E+     + W    T         ++N+     I+FR+   N  
Sbjct: 759  RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 818

Query: 1947 GVSLP-TESQSVRLEKHATVPS----PPTAPLEIRMVGS--NIVMTSWGTPE----W-DG 1994
            G + P T +Q V + + A  P            IR VG   N+V+   G P     W  G
Sbjct: 819  GRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG 878

Query: 1995 GAPLLGYNIAIR 2006
            GAPL    + +R
Sbjct: 879  GAPLDTSRVHVR 890



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 69/309 (22%), Positives = 124/309 (40%), Gaps = 25/309 (8%)

Query: 1282 EVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPS 1337
            E+ E PPKI       + Y  K G  + L+V +Q  P+P   W      +   + H + S
Sbjct: 834  EIAE-PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTS 892

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
                     +++   +D+G Y+L ++         + + +++K  PP    + E+  ++ 
Sbjct: 893  --DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 950

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456
             + W  P++ GNS I+ Y V+  +  T EW +V    + T  ++ +L   + Y FR Y  
Sbjct: 951  LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1010

Query: 1457 NEVDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIELTC 1503
            N   +SD+   ++    I +T I              +P    PL +          L C
Sbjct: 1011 NICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1070

Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
               G P+PKV W ++  ++    K     Y+                 Y C A N+ GE 
Sbjct: 1071 AVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1130

Query: 1560 ETSCVVGIQ 1568
               C + ++
Sbjct: 1131 LAECKLEVR 1139



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 6/136 (4%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            IE+ + +DE  + I   N VG  +     S+ L+    VP PP A + I  VG +  +  
Sbjct: 606  IESAQREDEGRYTIKVTNPVGEDVA----SIFLQV-VDVPDPPEA-VRITSVGEDWAILV 659

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P +DGG P+ GY +  +      WM++         +    + E   Y +R++A N 
Sbjct: 660  WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 719

Query: 2047 IGLSEPLESDEPFKVI 2062
            IG+S+P  + +PF  I
Sbjct: 720  IGVSQPSMNTKPFMPI 735



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            MAP F+  L  +    G +    C V G+P+P++ W +    I+    F +  +   V T
Sbjct: 1047 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLT 1105

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            L IR   P DAGT+TC A N  G A +  +L V  P
Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1141



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 43/198 (21%), Positives = 74/198 (37%), Gaps = 7/198 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P    ++        L W  P  +GG P+T Y++E K    + W K+     +  E 
Sbjct: 640  PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT--ET 697

Query: 1926 CIENIKEKDEIIF--RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
              E+ K  + I++  R+ A N +GVS P+ +    +      P+     L +  V     
Sbjct: 698  TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP---IAPTSEPLHLIVEDVTDTTT 754

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
               W  P   G   + GY +         W+      V    F +++L      + R+  
Sbjct: 755  TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 814

Query: 2044 RNEIGLSEPLESDEPFKV 2061
             N  G +EP    +P  +
Sbjct: 815  VNIAGRTEPATLAQPVTI 832



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 85/331 (25%), Positives = 127/331 (38%), Gaps = 48/331 (14%)

Query: 636 FSKKPKAQY-VDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYC 692
           F+KK    Y VD G+ I L   +V I +PD+   W   G+EI P                
Sbjct: 258 FTKKLDPAYQVDRGNKIKL---MVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKR--- 311

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGES 751
            +L I       +  Y V   + +    L +        KEPP  ++ PL+   V  G+ 
Sbjct: 312 -ILTINKCTLADDAAYEVAVKDEKCFTELFV--------KEPPVLIVTPLEDQQVFVGDR 362

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT-------KSDGDTHSITILKPKKVKDEGVYT 804
           V ++ +V       + W K+   +    +       K DG  H I I      +D G Y 
Sbjct: 363 VEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRH-ILIFSDVVQEDRGRYQ 420

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
           +     +  AE    + VEE   E       +    ++TVK          V+   V   
Sbjct: 421 VITNGGQCEAE----LIVEEKQLE------VLQDIADLTVKASEQAVFKCEVSDEKVTG- 469

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            WY+N   + PS+ IT +  G   +LVI +V  E D GDY  V    A   S  A++   
Sbjct: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE-DEGDYTFVPDGYA-LGSLSAKLNFL 527

Query: 925 VEKVTFVK-------HLQKSYETEEGKTVIL 948
             KV +V        HL  S +T E   V++
Sbjct: 528 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 558



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 53/262 (20%), Positives = 102/262 (38%), Gaps = 22/262 (8%)

Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
           + W+  G E+  +++              +L  ++V +   G Y V+    + EA L + 
Sbjct: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIV- 434

Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTK 781
                 E++  +V++ +  + V+  E  +   +V  + + T  W KN    +P K +   
Sbjct: 435 ------EEKQLEVLQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITIS 487

Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE---NAEPPLF--- 835
             G  H + ++   + +DEG YT    +   +   SA +   E   E     EPP     
Sbjct: 488 HVGRFHKL-VIDDVRPEDEGDYTF-VPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLD 545

Query: 836 -INRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
              +  E  I V     ++L   +T  P P  TW + +E+ + +E  T+     +    +
Sbjct: 546 CSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 605

Query: 893 TNVDSEIDSGDYKCVASNSAGK 914
                  D G Y    +N  G+
Sbjct: 606 IESAQREDEGRYTIKVTNPVGE 627



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSIT 790
            P+ + PL   +V  G S  L+  V G+P+P + W KN   +    K L T   G   ++ 
Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLN 1107

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            I +P    D G YT +A N  G A     + V  P
Sbjct: 1108 IRRPSPF-DAGTYTCRAVNELGEALAECKLEVRVP 1141



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 21/178 (11%)

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE-GEASLPI-V 724
           W   G E+ P + I+++     H     L I +V+   EG YT V      G  S  +  
Sbjct: 471 WYKNGVEVRPSKRITISHVGRFHK----LVIDDVRPEDEGDYTFVPDGYALGSLSAKLNF 526

Query: 725 LKIKTG---EKEPPQVIEPLK------SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
           L+IK     ++EPP++           +++V  G  + L   + G P P  TW K ++  
Sbjct: 527 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 586

Query: 776 KALPTKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETS---AVITVEEPTE 827
                ++  +     S  +++  + +DEG YT+K  N  G    S    V+ V +P E
Sbjct: 587 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 644



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 19/71 (26%), Positives = 33/71 (46%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +   + G P P+V+W KN  ++  D ++ IT  +    + I+      +  YT  A N  
Sbjct: 1068 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNEL 1127

Query: 1652 GTSSVEVTLKV 1662
            G +  E  L+V
Sbjct: 1128 GEALAECKLEV 1138



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 10/133 (7%)

Query: 708 YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNP 762
           + VV VN  G      + +  T  +  EPP++  P  L+   +R+ GE + L     G P
Sbjct: 810 FRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 869

Query: 763 RPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
           RP + W K   P+          D  ++  ++     D G Y L  +  E + +T+   T
Sbjct: 870 RPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ-IENMKDTA---T 925

Query: 822 VEEPTEENAEPPL 834
           +     E A PP+
Sbjct: 926 IRIRVVEKAGPPI 938


>UniRef50_UPI00015A6D36 Cluster: UPI00015A6D36 related cluster; n=2;
            Danio rerio|Rep: UPI00015A6D36 UniRef100 entry - Danio
            rerio
          Length = 2222

 Score =  228 bits (557), Expect = 1e-57
 Identities = 253/1076 (23%), Positives = 438/1076 (40%), Gaps = 74/1076 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +  +P +F K+ K Q  +EG  + L C L     P + WL   + + P E   +      
Sbjct: 448  VNAVPISFIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMR----- 501

Query: 689  HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            H+   + L I N      GTY  V  ++  +A +    KI+T   +P    + L++ +  
Sbjct: 502  HIVTILELVIRNPVPEDSGTYICVCEDQSTKADI----KIRT---QPITFKQKLRNQMTE 554

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
            +G SVIL  ++     P + W K N  +K+           I  LK   +  +D G+Y+ 
Sbjct: 555  EGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKIRQKGCILELKIFNLTQEDSGLYSC 613

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             +E     AET+A +TV      +  P  F    +     E G+I L   ++++  P + 
Sbjct: 614  ASET----AETAANVTV------SGAPATFKQDLKNQEALEGGSITLHCELSKSDAP-VE 662

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W + +++I P        +G+  ELVI+NV  E D+G Y CV     G     A V +  
Sbjct: 663  WRKGDKLILPGPRFQMRLNGKTAELVISNVFPE-DAGTYSCVT----GDQKTTAEVKVKR 717

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXX 984
               TF K   KS E +EG +V L C+ S      +W+  ++ +   +  ++  +      
Sbjct: 718  LPATF-KATLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAEL 776

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D GV +C+  +Q+T  ++ V      F ++L++ E  E +  IL  E++  +
Sbjct: 777  LIRKAQPEDSGVYRCVCGEQKTEAIIKVNALPITFKQELKNQEGDEGNNVILRCELSKAS 836

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            ADV W +  E++ P + KY   + G   +L IR     D G Y C+  D++  A V +  
Sbjct: 837  ADVEWMKGEEVLTPGE-KYQMRQIGTKLELVIRKAIPEDSGVYICVCPDQTSKATVKINA 895

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
             P      L+NQ+V +GN      EL+K  A V+W+K    +   +  Q+ I+G+  +L 
Sbjct: 896  TPITFKQNLRNQEVTEGNTVALRCELSKPGATVKWWKGAEMLLAGDRYQMRIEGRIAELL 955

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I + + +D G YSC  G  K  A + V  P I F ++L    +   N    L  E+    
Sbjct: 956  IKNVNSEDVGSYSCTTGKEKTVAEVKVRVPPITFKVKLKNQEVEEEN-KLTLHCELSKAG 1014

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              V W K + V+    K+ +  +   R LII     +D   Y+C+  + K  TK  V V 
Sbjct: 1015 CPVEWRKGEEVLRPGYKYQIRENDVARELIIMSAMPEDSGVYSCICGEQK--TKATVRVF 1072

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
              P       +      G  V L  +      P   W+   + I      K   +  +A 
Sbjct: 1073 ATPVTFKQNLKNQEAPEGGVVVLHCELSKAGVP-VTWLKGDEEIYSGTKYKIKQEGLAAE 1131

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            L IK V   D G Y   + +    A+V +    L         +  E +++ ++    +P
Sbjct: 1132 LHIKNVLPMDVGEYSCIIGDQRTTAEVNVRERPLFFCGELQNQDAEEGETAFLSCELSQP 1191

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
                       +++     + ++   ++  + Q  I +L +  S  +R  A       D 
Sbjct: 1192 AVAVEWKKGAVILK----PSYKFEMKQDGCELQLQINDLTSQDSGAYRCCA-------DG 1240

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
             ET      +KE  +      + L+N  TE  E   L C     P     W +    LK 
Sbjct: 1241 IETRASI-TVKERPL---FFREELQNQETEEGETAFLCCEL-SKPGVPAQWKKGAMLLKN 1295

Query: 1525 A---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
                  T E N                Y+C A    G +ET   + +++KP+        
Sbjct: 1296 GHKYSMTQEGNEVLLQIHDLTSQDSGIYRCCA----GNLETRANIVVKEKPLFFFEELHN 1351

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
            +Q  +    +L   + +  P  EV W K   +L    +Y +        ++I +L    S
Sbjct: 1352 QQAEEGETAFLCCELSK--PGVEVQWKKGAIRLRPGNKYEMKQDGCKVQLQIHDLTSEDS 1409

Query: 1641 SKYTIEASNTAGTSSV---EVTLKVYDKPSKPEG-----PVIMREISRESVTIEWK 1688
              Y   + + A T+S+   E++L   ++    E       ++  E+S+  V+++W+
Sbjct: 1410 GTYKCCSGSLATTASIVVKELSLFFSEELQNHEAEEGKTAILSCELSKPGVSVQWR 1465



 Score =  194 bits (472), Expect = 3e-47
 Identities = 209/854 (24%), Positives = 357/854 (41%), Gaps = 86/854 (10%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F + LR +   +G+TV   C++   P   + W++   ++     +QM  +   +A L+I+
Sbjct: 900  FKQNLRNQEVTEGNTVALRCELSK-PGATVKWWKGAEMLLAGDRYQMRIEG-RIAELLIK 957

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
             V  ED            G  S TT           G E TV            A++   
Sbjct: 958  NVNSEDV-----------GSYSCTT-----------GKEKTV------------AEVKVR 983

Query: 632  IPP-TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMH 689
            +PP TF  K K Q V+E + + L C L     P + W  KGEE++ P     +  E+D+ 
Sbjct: 984  VPPITFKVKLKNQEVEEENKLTLHCELSKAGCP-VEWR-KGEEVLRPGYKYQIR-ENDV- 1039

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L I +      G Y+ +   ++ +A++ +          P    + LK+    +G
Sbjct: 1040 --ARELIIMSAMPEDSGVYSCICGEQKTKATVRVFAT-------PVTFKQNLKNQEAPEG 1090

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK 806
              V+L  ++     P +TW K ++ + +      K +G    + I K     D G Y+  
Sbjct: 1091 GVVVLHCELSKAGVP-VTWLKGDEEIYSGTKYKIKQEGLAAELHI-KNVLPMDVGEYSCI 1148

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
                 G   T+A + V E       P  F    Q    +E  T  L   +++ P  ++ W
Sbjct: 1149 I----GDQRTTAEVNVRE------RPLFFCGELQNQDAEEGETAFLSCELSQ-PAVAVEW 1197

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             +   I+ PS       DG  ++L I ++ S+ DSG Y+C A     ++S    +T+   
Sbjct: 1198 KKGAVILKPSYKFEMKQDGCELQLQINDLTSQ-DSGAYRCCADGIETRAS----ITVKER 1252

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             + F + LQ   ETEEG+T  L C+ S   V  +W      +       + QEG      
Sbjct: 1253 PLFFREELQNQ-ETEEGETAFLCCELSKPGVPAQWKKGAMLLKNGHKYSMTQEGNEVLLQ 1311

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D G+ +C   + ET   +VVKE    F  +L + + +E + A L  E++    
Sbjct: 1312 IHDLTSQDSGIYRCCAGNLETRANIVVKEKPLFFFEELHNQQAEEGETAFLCCELSKPGV 1371

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            +V W++    ++P  NKY+ ++ G   +L I + +  D G Y C     + TA + V EL
Sbjct: 1372 EVQWKKGAIRLRPG-NKYEMKQDGCKVQLQIHDLTSEDSGTYKCCSGSLATTASIVVKEL 1430

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
                   LQN +  +G  A    EL+K    V+W K    ++ S   ++  DG +Q+L+I
Sbjct: 1431 SLFFSEELQNHEAEEGKTAILSCELSKPGVSVQWRKGTVLLKLSKRYEIKQDGCQQQLQI 1490

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
            ++    D+G Y+C  G+   TA L V+E  + F   L        NT      E+    +
Sbjct: 1491 HELTAQDSGTYTCCAGSLITTASLLVKEKPLFFCDVLQNQEAEEGNT-VIFRCELSKPGV 1549

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
             V W K  ++++ ++K+ +  D  K  L + + T  D   Y C      +T  L V+   
Sbjct: 1550 SVQWKKGTALLKPSQKYEIKEDGCKLQLNVHELTAQDSGTYKCCAGSLVTTASLVVK--- 1606

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
               ++ + E E     G  V L  +  +    + +W     ++K  K  +   D +   L
Sbjct: 1607 --EELQNQESE----EGKTVILCCEL-SNTGVSVQWKKGMVLLKPSKKFEIKQDGRQLQL 1659

Query: 1346 TIKKVENTDAGIYK 1359
             I ++   D+G YK
Sbjct: 1660 QIHELTTQDSGTYK 1673



 Score =  192 bits (469), Expect = 7e-47
 Identities = 188/748 (25%), Positives = 309/748 (41%), Gaps = 53/748 (7%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            FS++ +    +EG   +L C L + P   + W  KG  ++    +S   E         L
Sbjct: 1434 FSEELQNHEAEEGKTAILSCEL-SKPGVSVQWR-KGTVLL---KLSKRYEIKQDGCQQQL 1488

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            +I  +     GTYT  A +    ASL +       +++P    + L++    +G +VI  
Sbjct: 1489 QIHELTAQDSGTYTCCAGSLITTASLLV-------KEKPLFFCDVLQNQEAEEGNTVIFR 1541

Query: 756  AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             ++   P  ++ W K     KP +    K DG    + + +    +D G Y   A +   
Sbjct: 1542 CEL-SKPGVSVQWKKGTALLKPSQKYEIKEDGCKLQLNVHE-LTAQDSGTYKCCAGS--- 1596

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            +  T++++  EE   + +E              E  T+ L   ++   V S+ W +   +
Sbjct: 1597 LVTTASLVVKEELQNQESE--------------EGKTVILCCELSNTGV-SVQWKKGMVL 1641

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            + PS+      DG  ++L I  + ++ DSG YKC A N    +S    + +    + F K
Sbjct: 1642 LKPSKKFEIKQDGRQLQLQIHELTTQ-DSGTYKCCAGNLVTTAS----LMVKEPPIFFRK 1696

Query: 933  HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            +LQ S E EEGK   L+C+ S   V+ +W      +      E+ Q G            
Sbjct: 1697 NLQ-SLEAEEGKMATLKCELSKAGVAVQWKKGTVLLKPGKKYEMKQNGCLLQLQINDLKS 1755

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D G   C      T+  LVVK     F R+LQ+    E   A+   E++   A V W R
Sbjct: 1756 EDSGSYLCCSGSIMTTASLVVKGLPITFKRELQNQVSIEGGSAVFTCELSKPGAPVEW-R 1814

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
             G +I     KY     G + KL I N    D G Y+C  +D   TAE+TV  LP     
Sbjct: 1815 KGRVILKAGAKYHTTLEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAELTVQGLPATFKA 1874

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             L++Q+V +GN  T   EL+K    V W+K    ++     QL     K +L I     +
Sbjct: 1875 TLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKAQSE 1934

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            D+G Y C  G  K  AI+ V    I F   L    +   NT A L  E+      V W+K
Sbjct: 1935 DSGVYRCVCGEQKTEAIIKVNATPITFKQNLRNQEVTEGNTVA-LRCELSKPGATVKWWK 1993

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
               ++   E++ +  + +   L+I+    +D   Y+C +   K+  ++KV  +      V
Sbjct: 1994 GAEMLLAGERYQMRIEGRIAELLIKNVNSEDVGSYSCTMGKEKTVAEVKVRALP-----V 2048

Query: 1292 DYEREYR---IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
             ++RE +    K G       +    P    +W     I+K     +   +     L I 
Sbjct: 2049 TFKRELQNEVTKEGGQAVFSCELSK-PGAQVDWRKGRVILKADDKYEMKQEGTFTQLFIH 2107

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVT 1376
             VE +DAG Y  + +++   A++ +  T
Sbjct: 2108 NVEPSDAGNYSCKTKDSESTAELTVKAT 2135



 Score =  185 bits (451), Expect = 1e-44
 Identities = 183/779 (23%), Positives = 320/779 (41%), Gaps = 42/779 (5%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +   P TF +  + Q V EG+ + L C L + P   + W    E ++  +   + IE  +
Sbjct: 893  INATPITFKQNLRNQEVTEGNTVALRCEL-SKPGATVKWWKGAEMLLAGDRYQMRIEGRI 951

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVR 747
                + L I NV     G+Y+       G+      +K++     PP   +  LK+  V 
Sbjct: 952  ----AELLIKNVNSEDVGSYSCTT----GKEKTVAEVKVRV----PPITFKVKLKNQEVE 999

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTL 805
            +   + L  ++     P + W K  + ++        + D     I+     +D GVY+ 
Sbjct: 1000 EENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKYQIRENDVARELIIMSAMPEDSGVYSC 1058

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
                  G  +T A + V       A P  F    +     E G + L   +++  VP +T
Sbjct: 1059 IC----GEQKTKATVRVF------ATPVTFKQNLKNQEAPEGGVVVLHCELSKAGVP-VT 1107

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W + +E I          +G   EL I NV   +D G+Y C+     G     A V +  
Sbjct: 1108 WLKGDEEIYSGTKYKIKQEGLAAELHIKNV-LPMDVGEYSCII----GDQRTTAEVNVRE 1162

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              + F   LQ   + EEG+T  L C+ S   V+ +W      +      E+ Q+G     
Sbjct: 1163 RPLFFCGELQNQ-DAEEGETAFLSCELSQPAVAVEWKKGAVILKPSYKFEMKQDGCELQL 1221

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G  +C     ET   + VKE    F  +LQ+ E +E + A L  E++   
Sbjct: 1222 QINDLTSQDSGAYRCCADGIETRASITVKERPLFFREELQNQETEEGETAFLCCELSKPG 1281

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
                W++   ++K   +KY   + G+   L I + +  D G Y C   +    A + V E
Sbjct: 1282 VPAQWKKGAMLLK-NGHKYSMTQEGNEVLLQIHDLTSQDSGIYRCCAGNLETRANIVVKE 1340

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
             P      L NQ+  +G  A    EL+K    V+W K    ++  N  ++  DG K +L+
Sbjct: 1341 KPLFFFEELHNQQAEEGETAFLCCELSKPGVEVQWKKGAIRLRPGNKYEMKQDGCKVQLQ 1400

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I+D   +D+G Y C  G+   TA + V+E S+ F+  L         T A L+ E+    
Sbjct: 1401 IHDLTSEDSGTYKCCSGSLATTASIVVKELSLFFSEELQNHEAEEGKT-AILSCELSKPG 1459

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            + V W K   +++ ++++ +  D  ++ L I + T  D   YTC      +T  L V+  
Sbjct: 1460 VSVQWRKGTVLLKLSKRYEIKQDGCQQQLQIHELTAQDSGTYTCCAGSLITTASLLVK-- 1517

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            E P    D  +    + G+ V    +    P  + +W   + ++K  +  +   D     
Sbjct: 1518 EKPLFFCDVLQNQEAEEGNTVIFRCELSK-PGVSVQWKKGTALLKPSQKYEIKEDGCKLQ 1576

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICW 1401
            L + ++   D+G YK    +    A + +   + ++ S  GK  IL  E+ ++ +++ W
Sbjct: 1577 LNVHELTAQDSGTYKCCAGSLVTTASLVVKEELQNQESEEGKTVILCCELSNTGVSVQW 1635



 Score =  179 bits (435), Expect = 9e-43
 Identities = 232/1082 (21%), Positives = 416/1082 (38%), Gaps = 84/1082 (7%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++  IP  F+K+ + Q V EG  + L C   +IP     W  KG E +     S      
Sbjct: 358  LVRAIPAEFTKELQNQEVKEGESVTLMCE-YSIPGIQFVWR-KGPETLKS---SEKYHMR 412

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                C  L I NVK    G YT +  +++  A++       T    P   I+ LK+    
Sbjct: 413  QRKSCISLAIHNVKPDDSGNYTCICRDQKTMATV-------TVNAVPISFIKELKNQETE 465

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL----KPKKVKDEGVY 803
            +G+++ L  ++     P + W K  + +   P +     H +TIL    +    +D G Y
Sbjct: 466  EGKTMTLRCELSKAGVP-VEWLKGKQTL--CPGEKYQMRHIVTILELVIRNPVPEDSGTY 522

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
                E+      T A I +        +P  F  + +    +E  ++ L   +++  +P 
Sbjct: 523  ICVCEDQ----STKADIKI------RTQPITFKQKLRNQMTEEGSSVILHCEISKADIP- 571

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + W + N ++   E       G  +EL I N+  E DSG Y C AS +A      A VT+
Sbjct: 572  VEWRKGNILLKSGEKYKIRQKGCILELKIFNLTQE-DSGLYSC-ASETA---ETAANVTV 626

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982
                 TF + L K+ E  EG ++ L C+ S +    +W    K I      ++   G+  
Sbjct: 627  SGAPATFKQDL-KNQEALEGGSITLHCELSKSDAPVEWRKGDKLILPGPRFQMRLNGKTA 685

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C+  DQ+T+  + VK     F   L+  EV+E +   L  E++ 
Sbjct: 686  ELVISNVFPEDAGTYSCVTGDQKTTAEVKVKRLPATFKATLKSQEVQEGNSVTLNCELSK 745

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
                V W +  E++K  + KY    +    +L IR     D G Y C+  ++   A + V
Sbjct: 746  AGGRVEWWKGEEMLKTGE-KYQLRHKEAKAELLIRKAQPEDSGVYRCVCGEQKTEAIIKV 804

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
              LP      L+NQ+ ++GN      EL+K  A V W K    +      Q+   G K +
Sbjct: 805  NALPITFKQELKNQEGDEGNNVILRCELSKASADVEWMKGEEVLTPGEKYQMRQIGTKLE 864

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            L I     +D+G Y C   +    A + +    I F   L    +   NT A L  E+  
Sbjct: 865  LVIRKAIPEDSGVYICVCPDQTSKATVKINATPITFKQNLRNQEVTEGNTVA-LRCELSK 923

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
                V W+K   ++   +++ +  + +   L+I+    +D   Y+C     K+  ++KV 
Sbjct: 924  PGATVKWWKGAEMLLAGDRYQMRIEGRIAELLIKNVNSEDVGSYSCTTGKEKTVAEVKVR 983

Query: 1283 V--VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V  + F  K+ + E    ++  + +TL  +      P  EW    ++++     +   + 
Sbjct: 984  VPPITFKVKLKNQE----VEEENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKYQIREND 1038

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
             +  L I      D+G+Y       CG    +  V +   P    K N+   ++      
Sbjct: 1039 VARELIIMSAMPEDSGVYSC----ICGEQKTKATVRVFATP-VTFKQNLKNQEA------ 1087

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
               PE  G   +++  +    +  T W+       + T  +  +   +       V  +D
Sbjct: 1088 ---PE--GGVVVLHCELSKAGVPVT-WLKGDEEIYSGTKYKIKQEGLAAELHIKNVLPMD 1141

Query: 1461 ISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            + + S      +   E  ++   +     L+N   E  E   L+C     P   V W + 
Sbjct: 1142 VGEYSCIIGDQRTTAEVNVRERPLFFCGELQNQDAEEGETAFLSCEL-SQPAVAVEWKKG 1200

Query: 1519 GKKLKTA-KATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
               LK + K   +                    Y+C A      +ET   + ++++P+  
Sbjct: 1201 AVILKPSYKFEMKQDGCELQLQINDLTSQDSGAYRCCA----DGIETRASITVKERPL-- 1254

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
               E+++ +     E          P     W K    L+N  +Y++T +    +++I +
Sbjct: 1255 FFREELQNQETEEGETAFLCCELSKPGVPAQWKKGAMLLKNGHKYSMTQEGNEVLLQIHD 1314

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVY--------DKPSKPEGPVIMREISRESVTIE 1686
            L    S  Y   A N    +++ V  K           +  + E   +  E+S+  V ++
Sbjct: 1315 LTSQDSGIYRCCAGNLETRANIVVKEKPLFFFEELHNQQAEEGETAFLCCELSKPGVEVQ 1374

Query: 1687 WK 1688
            WK
Sbjct: 1375 WK 1376



 Score =  178 bits (433), Expect = 2e-42
 Identities = 184/731 (25%), Positives = 289/731 (39%), Gaps = 41/731 (5%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            T  K+ +   V EG     EC L      +  W   G+ IV ++ I VA E   +     
Sbjct: 4    TIVKRIRTATVLEGESCSFECVLSHDITDEAFWNMNGQLIVSNQRIIVANEGRKY----T 59

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            + I  V     G    V  N + E S   +L +K   ++P +V   + ++    GE   L
Sbjct: 60   MSIEEVMTSDAGE---VVCNIK-ELSCRTMLFVK---EKPVRVFRDMLNVKATPGEDPEL 112

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEG 812
            S ++   P  T+ W KN + ++  P  +     H +  I+    + D G Y  +A+   G
Sbjct: 113  SCEIT-KPDATVKWLKNGRQIRVSPKYEITQKDHLVKLIIHNAAIMDSGEYCCEAD---G 168

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            IA T A + V +          F    +++  +EKG + L    TR P  ++TW +   +
Sbjct: 169  IA-TRARLDVRDLQHA------FAKELKDVFAEEKGIVVLECE-TRQPATTVTWLKGLMV 220

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV--EKVTF 930
            +              + L I N++   DS  Y C      G     A +T+    +KV  
Sbjct: 221  LRSGHKYIMKKKDVLLTLTIFNLEKS-DSAVYIC----DVGMMQSRALLTVQFSGQKVVI 275

Query: 931  VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
            V  L+   E  EG+T+I  C+   S     KWY ++  +   D  EI+   G        
Sbjct: 276  VDELEDK-ECLEGETIIFRCRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTFK 334

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D G I     D+ +   L+V+    EF ++LQ+ EVKE +   L  E +      
Sbjct: 335  QLARKDTGTIIFEAGDKRSYASLLVRAIPAEFTKELQNQEVKEGESVTLMCEYSIPGIQF 394

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
            VW +  E +K  + KY   +R     L I N    D G Y+CI RD+   A VTV  +P 
Sbjct: 395  VWRKGPETLKSSE-KYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQKTMATVTVNAVPI 453

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
              I  L+NQ+  +G   T   EL+K    V W K    +      Q+       +L I +
Sbjct: 454  SFIKELKNQETEEGKTMTLRCELSKAGVPVEWLKGKQTLCPGEKYQMRHIVTILELVIRN 513

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
               +D+G Y C   +    A + +    I F  +L    +    +   L  EI    + V
Sbjct: 514  PVPEDSGTYICVCEDQSTKADIKIRTQPITFKQKLRN-QMTEEGSSVILHCEISKADIPV 572

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287
             W K   +++  EK+ +        L I   T++D   Y+C    A+  T   V V   P
Sbjct: 573  EWRKGNILLKSGEKYKIRQKGCILELKIFNLTQEDSGLYSCASETAE--TAANVTVSGAP 630

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
                   +      G  +TL  +      P  EW    K+I      +  ++ K+A L I
Sbjct: 631  ATFKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNGKTAELVI 689

Query: 1348 KKVENTDAGIY 1358
              V   DAG Y
Sbjct: 690  SNVFPEDAGTY 700



 Score =  173 bits (421), Expect = 4e-41
 Identities = 152/592 (25%), Positives = 248/592 (41%), Gaps = 34/592 (5%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVI 753
            L+I  +     GTY   A N    ASL +        KEPP      L+S+   +G+   
Sbjct: 1659 LQIHELTTQDSGTYKCCAGNLVTTASLMV--------KEPPIFFRKNLQSLEAEEGKMAT 1710

Query: 754  LSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            L  ++       + W K     KP K    K +G    + I    K +D G Y       
Sbjct: 1711 LKCEL-SKAGVAVQWKKGTVLLKPGKKYEMKQNGCLLQLQI-NDLKSEDSGSYLC----C 1764

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G   T+A + V+        P  F    Q     E G+      +++   P + W +  
Sbjct: 1765 SGSIMTTASLVVK------GLPITFKRELQNQVSIEGGSAVFTCELSKPGAP-VEWRKGR 1817

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
             I+          +G   +L I N+  E D+G+Y C   +S       A +T+     TF
Sbjct: 1818 VILKAGAKYHTTLEGRLTKLAINNL-VEGDAGNYTCKTKDSQST----AELTVQGLPATF 1872

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
             K   KS E +EG +V L C+ S      +W+  ++ +   +  ++  +           
Sbjct: 1873 -KATLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKA 1931

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
               D GV +C+  +Q+T  ++ V  T   F + L++ EV E +   L  E++   A V W
Sbjct: 1932 QSEDSGVYRCVCGEQKTEAIIKVNATPITFKQNLRNQEVTEGNTVALRCELSKPGATVKW 1991

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             +  E++   + +Y     G I +L I+N +  D G YSC +  E   AEV V  LP   
Sbjct: 1992 WKGAEMLLAGE-RYQMRIEGRIAELLIKNVNSEDVGSYSCTMGKEKTVAEVKVRALPVTF 2050

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
               LQN+   +G +A F  EL+K  A V W K    ++  +  ++  +G   +L I++ +
Sbjct: 2051 KRELQNEVTKEGGQAVFSCELSKPGAQVDWRKGRVILKADDKYEMKQEGTFTQLFIHNVE 2110

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
              DAG YSC+  +S+ TA LTV+   + F   L      P      L  E+    + VTW
Sbjct: 2111 PSDAGNYSCKTKDSESTAELTVKATPVTFKQNLKN-QEAPEGGVVVLHCELSKAGVPVTW 2169

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
             K    I    K+ +  +     L I+     D  EY+C++ D ++T ++ V
Sbjct: 2170 LKGDEEIYSGTKYKIKQEGLAAELHIKNVLPMDVGEYSCIIGDQRTTAEVNV 2221



 Score =  147 bits (357), Expect = 3e-33
 Identities = 128/478 (26%), Positives = 203/478 (42%), Gaps = 34/478 (7%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +++G+P TF ++ + Q   EG   +  C L + P   + W  KG  I+          + 
Sbjct: 1775 VVKGLPITFKRELQNQVSIEGGSAVFTCEL-SKPGAPVEWR-KGRVIL---KAGAKYHTT 1829

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            +    + L I N+ +   G YT    + +  A L       T +  P      LKS  V+
Sbjct: 1830 LEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAEL-------TVQGLPATFKATLKSQEVQ 1882

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTL 805
            +G SV L+ + +      + W K  + +K          +  +  +++  + +D GVY  
Sbjct: 1883 EGNSVTLNCE-LSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKAQSEDSGVYRC 1941

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
                  G  +T A+I V      NA P  F    +   V E  T+ L   +++ P  ++ 
Sbjct: 1942 VC----GEQKTEAIIKV------NATPITFKQNLRNQEVTEGNTVALRCELSK-PGATVK 1990

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W++  E++   E      +G   EL+I NV+SE D G Y C    + GK    A V +  
Sbjct: 1991 WWKGAEMLLAGERYQMRIEGRIAELLIKNVNSE-DVGSYSC----TMGKEKTVAEVKVRA 2045

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              VTF + LQ    T+EG   +  C+ S       W   +  +   D  E+ QEG     
Sbjct: 2046 LPVTFKRELQNEV-TKEGGQAVFSCELSKPGAQVDWRKGRVILKADDKYEMKQEGTFTQL 2104

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G   C  KD E++  L VK T   F + L++ E  E  V +L  E++   
Sbjct: 2105 FIHNVEPSDAGNYSCKTKDSESTAELTVKATPVTFKQNLKNQEAPEGGVVVLHCELSKAG 2164

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
              V W +  E I     KY  ++ G   +L+I+N    D GEYSCI+ D+  TAEV V
Sbjct: 2165 VPVTWLKGDEEIY-SGTKYKIKQEGLAAELHIKNVLPMDVGEYSCIIGDQRTTAEVNV 2221



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 96/389 (24%), Positives = 159/389 (40%), Gaps = 35/389 (8%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++G+P TF    K+Q V EG+ + L C L +     + W +KGEE++           + 
Sbjct: 1865 VQGLPATFKATLKSQEVQEGNSVTLNCEL-SKAGGRVEW-WKGEEMLKTGEKYQLRHKEA 1922

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
                + L I   +    G Y  V     GE     ++K+      P    + L++  V +
Sbjct: 1923 K---AELLIRKAQSEDSGVYRCVC----GEQKTEAIIKVNA---TPITFKQNLRNQEVTE 1972

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            G +V L  + +  P  T+ W K  + + A      G+ + + I    ++ +     +K  
Sbjct: 1973 GNTVALRCE-LSKPGATVKWWKGAEMLLA------GERYQMRI--EGRIAE---LLIKNV 2020

Query: 809  NSEGIAETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            NSE +   S  +  E+   E    A P  F    Q    KE G       +++ P   + 
Sbjct: 2021 NSEDVGSYSCTMGKEKTVAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSK-PGAQVD 2079

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W +   I+   +      +G   +L I NV+   D+G+Y C   +S       A +T+  
Sbjct: 2080 WRKGRVILKADDKYEMKQEGTFTQLFIHNVEPS-DAGNYSCKTKDSEST----AELTVKA 2134

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              VTF ++L K+ E  EG  V+L C+ S   V   W    +EI      +I QEG     
Sbjct: 2135 TPVTFKQNL-KNQEAPEGGVVVLHCELSKAGVPVTWLKGDEEIYSGTKYKIKQEGLAAEL 2193

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
                    DVG   CI+ DQ T+  + V+
Sbjct: 2194 HIKNVLPMDVGEYSCIIGDQRTTAEVNVR 2222



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F + L+ +   +G ++   C++     P + W +   +I P   FQM  +    A LVI 
Sbjct: 633 FKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNG-KTAELVIS 690

Query: 572 EVFPEDAGTFTCV 584
            VFPEDAGT++CV
Sbjct: 691 NVFPEDAGTYSCV 703



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 2/76 (2%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F+++L+ + T +G T+   C++     P + W +    + P + +QM +    +  LVIR
Sbjct: 455 FIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMRHIV-TILELVIR 512

Query: 572 EVFPEDAGTFTCVAKN 587
              PED+GT+ CV ++
Sbjct: 513 NPVPEDSGTYICVCED 528



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 8/106 (7%)

Query: 499  EKPTSEEQSMA-PI-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            EK  +E +  A P+ F  +L+ + T +G    F C++   P  Q+ W +   I+K    +
Sbjct: 2035 EKTVAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSK-PGAQVDWRKGRVILKADDKY 2093

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            +M   +     L I  V P DAG ++C  K+    + ST EL V+A
Sbjct: 2094 EMK-QEGTFTQLFIHNVEPSDAGNYSCKTKD----SESTAELTVKA 2134



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 2/88 (2%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F ++L+ +   +G +V   C+    P  Q  W +    +K S+ + M      ++ L I 
Sbjct: 366 FTKELQNQEVKEGESVTLMCEYS-IPGIQFVWRKGPETLKSSEKYHMRQRKSCIS-LAIH 423

Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELI 599
            V P+D+G +TC+ ++    A+ T   +
Sbjct: 424 NVKPDDSGNYTCICRDQKTMATVTVNAV 451



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            + ++  F E+L+     +G T    C++   P   + W + T ++K S+ +++  D    
Sbjct: 1428 KELSLFFSEELQNHEAEEGKTAILSCELSK-PGVSVQWRKGTVLLKLSKRYEIKQDGCQ- 1485

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPL 604
              L I E+  +D+GT+TC     AG   +T  L+V E PL
Sbjct: 1486 QQLQIHELTAQDSGTYTC----CAGSLITTASLLVKEKPL 1521



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 6/90 (6%)

Query: 514  EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
            E+L+ + + +G TV   C++       + W +   ++KPS+ F++  D   +  L I E+
Sbjct: 1607 EELQNQESEEGKTVILCCELSN-TGVSVQWKKGMVLLKPSKKFEIKQDGRQLQ-LQIHEL 1664

Query: 574  FPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              +D+GT+ C A N      +T  L+V+ P
Sbjct: 1665 TTQDSGTYKCCAGNLV----TTASLMVKEP 1690



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 2/72 (2%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F + LR +   +G+TV   C++   P   + W++   ++   + +QM  +   +A L+I+
Sbjct: 1961 FKQNLRNQEVTEGNTVALRCELSK-PGATVKWWKGAEMLLAGERYQMRIEG-RIAELLIK 2018

Query: 572  EVFPEDAGTFTC 583
             V  ED G+++C
Sbjct: 2019 NVNSEDVGSYSC 2030



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F ++L+ +   +G+ V   C++       + W +   ++ P + +QM      +  LVIR
Sbjct: 811 FKQELKNQEGDEGNNVILRCELSK-ASADVEWMKGEEVLTPGEKYQMRQIGTKLE-LVIR 868

Query: 572 EVFPEDAGTFTCVAKNAAGFAS 593
           +  PED+G + CV  +    A+
Sbjct: 869 KAIPEDSGVYICVCPDQTSKAT 890



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 4/88 (4%)

Query: 499 EKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
           +K T+E +   +   F   L+ +   +G++V   C++      ++ W++   ++K  + +
Sbjct: 707 QKTTAEVKVKRLPATFKATLKSQEVQEGNSVTLNCELSK-AGGRVEWWKGEEMLKTGEKY 765

Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCV 584
           Q+ + +   A L+IR+  PED+G + CV
Sbjct: 766 QLRHKEAK-AELLIRKAQPEDSGVYRCV 792



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 20/88 (22%), Positives = 43/88 (48%), Gaps = 4/88 (4%)

Query: 499  EKPTSEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            EK  +E +   P   F  KL+ +   + + +   C++     P + W +   +++P   +
Sbjct: 974  EKTVAEVKVRVPPITFKVKLKNQEVEEENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKY 1032

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCV 584
            Q+  ++D    L+I    PED+G ++C+
Sbjct: 1033 QIR-ENDVARELIIMSAMPEDSGVYSCI 1059



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 18/79 (22%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            Q +   F   L+ +   +G++V   C++      ++ W++   ++K  + +Q+ + +   
Sbjct: 1866 QGLPATFKATLKSQEVQEGNSVTLNCELSK-AGGRVEWWKGEEMLKTGEKYQLRHKEAK- 1923

Query: 566  ATLVIREVFPEDAGTFTCV 584
            A L+IR+   ED+G + CV
Sbjct: 1924 AELLIRKAQSEDSGVYRCV 1942



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F +KLR + T +GS+V   C++     P + W +   ++K  + +++      +  L I 
Sbjct: 544 FKQKLRNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKI-RQKGCILELKIF 601

Query: 572 EVFPEDAGTFTCVAKNAAGFASST 595
            +  ED+G ++C ++ A   A+ T
Sbjct: 602 NLTQEDSGLYSCASETAETAANVT 625


>UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome shotgun
            sequence; n=4; Tetraodontidae|Rep: Chromosome 1
            SCAF14995, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 5505

 Score =  227 bits (556), Expect = 2e-57
 Identities = 191/754 (25%), Positives = 330/754 (43%), Gaps = 46/754 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++ IP TF+++ K     EG++++L C L + P   + W  KGEE++ +      +   M
Sbjct: 946  VQAIPTTFTQQLKNIQAQEGTNVVLRCEL-SKPGIPVEWR-KGEELLKN-----GVRFQM 998

Query: 689  HMYCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                + L++   K   E  G Y+ V  +++  A++ I          P    + +K++ +
Sbjct: 999  RRRETTLELLIWKPVPEDSGVYSCVCGHQKSTATVRITAV-------PVTFKQKMKNVQI 1051

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVY 803
             +G   I   ++      ++ W K    V     K      DT     +   K  D  +Y
Sbjct: 1052 EEGNVAIFRCEL-SKAGQSVEWMKGGDAVIRGGEKYQMRQRDTLLELRISDVKPDDSDIY 1110

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            T    N     ET+A +TV      +A P  F  + + + V+E  ++ L   +++  +P 
Sbjct: 1111 TCICAN----IETTATLTV------HALPVTFKQKLKNVHVEEGNSLTLYCEISKPGIP- 1159

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + W R  +++   +          +EL I +VD E DSG Y CV  +   K    A V +
Sbjct: 1160 VEWRRGGDLLENGDKYQIKQREMALELTIRDVDPE-DSGVYTCVCRDQRTK----ATVKV 1214

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS---GMDHREIIQEG 979
                 +F   L KS + EEG +V L C+ S   V  +W  + + +S        ++  EG
Sbjct: 1215 VAVPASFKVSL-KSQDAEEGTSVSLCCELSKKGVHVQWKRDAQPLSEEMSPGKYQMKVEG 1273

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
            +            D G   C+  D++T+  + VK     F R +Q   VKE D  +L  E
Sbjct: 1274 KTAQLTIHGVQPEDAGRYSCVAGDEKTTAEVRVKALPVAFKRDIQSVAVKEGDRGVLCGE 1333

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            ++   +   W +   ++KP + KY+ ++ G + KL I +    D G+Y+C   +   TAE
Sbjct: 1334 LSRPGSQAEWRKGRVVLKPGR-KYEMKQEGCLVKLVINHVEESDAGKYTCKTNNSQSTAE 1392

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            +TV  LPP     L NQ+V +GN      EL+K  + V W K    ++  +  Q+     
Sbjct: 1393 LTVHGLPPTFRLPLVNQEVMEGNSVILHCELSKASSWVEWRKGKVLLKHGDKYQVRKKEL 1452

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            + ++KI D  + D GEYSC  G     A +TV+E  I F   L   + V    +  L  E
Sbjct: 1453 QVEMKILDLGVSDGGEYSCVCGEQTTRATITVKERPIKFLQELKN-VQVQEGNEVKLRCE 1511

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            I      V W K + V+ D EK+ +        L+IRKC  +D   Y+CV  + +ST  +
Sbjct: 1512 ISKAGASVEWKKGEKVLSDGEKYQMKQSGSILELVIRKCQPEDSGTYSCVCAEVRSTATI 1571

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
             +  +  P       R   +     VTL  +      P  EW   ++++K+ +  +   +
Sbjct: 1572 IITAI--PITFKQKLRNQEVVEEGSVTLRCELSKAGVP-VEWRKEAQLLKEGEKYQMRQE 1628

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             ++A +TI+ V   D G Y   +      A++++
Sbjct: 1629 GRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKV 1662



 Score =  211 bits (515), Expect = 2e-52
 Identities = 196/806 (24%), Positives = 348/806 (43%), Gaps = 69/806 (8%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            + + P F++ L+     +G T+  +C++   P   + W R   +++ ++ +++   +  +
Sbjct: 2404 KELPPFFIDCLQSVTAHEGDTLSLKCELSK-PGVAVQWKRNKVVLRSNRKYELK-QEGCL 2461

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
              L IR + PED G+++C A       S+ T  +V   + D  +  +             
Sbjct: 2462 LQLSIRGLTPEDHGSYSCHA------GSAETAALVTVKVRDTATIFSPTE---------- 2505

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
                  +PP F ++ ++  V+EG    L C    + +P ++  +K  ++V   +    ++
Sbjct: 2506 ------LPPFFKEELQSLEVEEGGAASLSC---VLSKPGVSVRWKKNKLVLRSSRKYEMK 2556

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
             D  +    L+I  +K    G+Y+  A + E  A + +        + PP   + L ++ 
Sbjct: 2557 QDGCLL--QLQIKGLKPEDAGSYSCHAGDAETTAMVAVT-------EVPPFFKKNLINVE 2607

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802
              +G    L  ++   P  ++ W KN  P++A      K DG    + +      +D G 
Sbjct: 2608 AEEGGVASLCCEL-SKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQLQV-SDLTPEDTGG 2665

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y+ +AE SE    TSAV+ V+E          F +  Q +  +E G + L   ++++ V 
Sbjct: 2666 YSCQAEMSE----TSAVLKVKE------HATFFSSDLQSVEAEESGAVTLCCELSKSGVS 2715

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             + W +N   +  S       DG  ++L I ++  E DSG Y C    SAG +   A + 
Sbjct: 2716 GVQWKKNGVPLRVSRKYEMKQDGRLLQLHIKDLTPE-DSGGYSC----SAGNAKTSANLV 2770

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
            +      F   L+ S E EEG +  L CQ S    S +W  N+  +      E+ Q+G  
Sbjct: 2771 VRELPPIFKMSLE-SVEVEEGSSASLRCQLSKPGASVQWKKNRMPLRADGKYEMKQDGCL 2829

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G   C      TS  + VKE  P FI +LQ  E +E   A L  E++
Sbjct: 2830 IQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITELQSVEAEEGGAASLCCELS 2889

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
                 V W+++  I     ++Y+ ++ G + +L+I+     D G ++C       +A VT
Sbjct: 2890 KPGVKVQWKKN-RIPLRGSSRYEMKQEGCLLQLHIQELRPEDGGVFTCQTESAETSASVT 2948

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V E        LQ+ K  +G  A+   EL+K  A V+W K+   ++     ++  DG   
Sbjct: 2949 VKE-------NLQSVKAEEGAAASLCCELSKPGASVQWKKNEVALRAGGRFEMKQDGCLI 3001

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
            +L++ D  L+D+G YSC  G +K +A L V E  + FT  L   + V   + A L  ++ 
Sbjct: 3002 QLQVKDLKLEDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQR-VEVEEGSSASLRCQLS 3060

Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
               + V W K +  +    K+ +  D     L I+    +D   YTC   +A+  T   V
Sbjct: 3061 KPGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAE--TSGAV 3118

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTL 1307
            EV   P   +   +    + G  V+L
Sbjct: 3119 EVKALPTLFITELQSVEAEEGGSVSL 3144



 Score =  187 bits (455), Expect = 3e-45
 Identities = 250/1214 (20%), Positives = 475/1214 (39%), Gaps = 88/1214 (7%)

Query: 502  TSEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            T+E    AP   F  KLR +   +  +V   C++   P   + W +    ++ S  +Q+ 
Sbjct: 1746 TAELTVRAPPVTFKTKLRSQQVEEEKSVTLSCELSK-PGLGVEWKKGQEQLQNSFKYQIR 1804

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
             +   +  L I+     D+G ++C      G   +T ++ V      +   + +      
Sbjct: 1805 -NRQGIMELTIKNTQLVDSGLYSC----NYGDVKTTADITVTRKGDPYTPFLFIHFSGAD 1859

Query: 620  XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
                        IP +F    K Q   EG ++ L C L     P + W     E+     
Sbjct: 1860 QLTNTFC--YSAIPLSFKTGLKNQEAPEGGNVALRCELSRTGVP-VQWFRSENELCHGGR 1916

Query: 680  ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKEPPQVI 738
              + +  ++    + + I N++    G Y+ V   ++  A + +        EKE     
Sbjct: 1917 YQMTLRGNV----AEMHIRNIQPEDVGEYSCVFGEQKTTAEVNVRAAASVFFEKE----- 1967

Query: 739  EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPK 795
              L+S  V +G+ V+LS +V     P +TW K+N  ++       K +G  HS+ I K  
Sbjct: 1968 --LESQAVLEGKPVLLSCEVSSANVP-VTWKKDNVVLEDGGRYILKKEGARHSLEIGK-L 2023

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
            +++D G +           +T+A + V E           +   Q++TV        V  
Sbjct: 2024 QLEDAGEFCCITRGK----KTTAQLVVRERVR-------IVTALQDVTVTAGEEANFVCE 2072

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            ++   +    W+  +  +  +E       G    LV+     E ++G    V       S
Sbjct: 2073 LSHADMAEGVWWLGSSPLQRNEMNQMTCQGRQRRLVLAMTTPE-ETGTVAFVVGEER-TS 2130

Query: 916  SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC-QTSHTVSTKWYHNKKEISGMDHRE 974
            +H   + +   KV F +   +     EG+T +L C  T  T    W  N   +   +  E
Sbjct: 2131 AH--LLVVPKPKVLF-EEKPRDLVVMEGETAVLSCVTTDFTSPVTWKCNHVPLRNGNKYE 2187

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
            + +EG+            D G+  C   D ++S  L V E  P F   LQ  EV+E   A
Sbjct: 2188 MHKEGKVNLLHIHDADPQDTGIYSCDTGDVQSSARLTVTERPPFFQDGLQSVEVEEGGSA 2247

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
             L  E++     V W++D   ++  + K++ ++ G   +L+IR+    D G Y C     
Sbjct: 2248 FLCCELSKPGVPVDWKKDRLPLRSSR-KHEIKQDGCFLQLHIRDLKPEDSGSYLCQAGSA 2306

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
              TA VTV EL P     L++ +V +G+ A+   EL+K  A V+W K+   ++     ++
Sbjct: 2307 ETTAVVTVKELRPFFTKELRDLEVEEGSSASLRCELSKPGASVQWKKNRMPLRAGGKFEM 2366

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
              DG   +L++ D   +D+G YSC   +++ +++++V+E    F +   + +        
Sbjct: 2367 KQDGCLFQLQMKDLVPEDSGSYSCHADSAETSSLVSVKELP-PFFIDCLQSVTAHEGDTL 2425

Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
             L  E+    + V W + K V+    K+ L  +     L IR  T +D   Y+C    A+
Sbjct: 2426 SLKCELSKPGVAVQWKRNKVVLRSNRKYELKQEGCLLQLSIRGLTPEDHGSYSCHAGSAE 2485

Query: 1275 STTKLKVEV---------VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            +   + V+V          E PP   +  +   ++ G   +L     + P  +  W  N 
Sbjct: 2486 TAALVTVKVRDTATIFSPTELPPFFKEELQSLEVEEGGAASLSC-VLSKPGVSVRWKKNK 2544

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
             +++  +  +   D     L IK ++  DAG Y      + G A+    V + + P P  
Sbjct: 2545 LVLRSSRKYEMKQDGCLLQLQIKGLKPEDAGSYSC----HAGDAETTAMVAVTEVP-PFF 2599

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLK 1444
            K N++ +++    +     E +     + +      +       +K +    Q  + +L 
Sbjct: 2600 KKNLINVEAEEGGVASLCCELSKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQLQVSDLT 2659

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
               +  +   A       + SET+   KV    K  +      L+++  E +  + L C 
Sbjct: 2660 PEDTGGYSCQA-------EMSETSAVLKV----KEHATFFSSDLQSVEAEESGAVTLCCE 2708

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSC 1563
                    V W ++G  L+ ++  YE +                    ++   G  +TS 
Sbjct: 2709 LSKSGVSGVQWKKNGVPLRVSR-KYEMKQDGRLLQLHIKDLTPEDSGGYSCSAGNAKTSA 2767

Query: 1564 VVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
             + +++  P+  +S E ++ +   G    +   +   P   V W KN   L  D +Y + 
Sbjct: 2768 NLVVRELPPIFKMSLESVEVEE--GSSASLRCQLSK-PGASVQWKKNRMPLRADGKYEMK 2824

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT------LKVYDKPSKPEGPV--I 1674
                   +++K+L+   S  Y+  A +   +++V V       +         EG    +
Sbjct: 2825 QDGCLIQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITELQSVEAEEGGAASL 2884

Query: 1675 MREISRESVTIEWK 1688
              E+S+  V ++WK
Sbjct: 2885 CCELSKPGVKVQWK 2898



 Score =  185 bits (450), Expect = 1e-44
 Identities = 171/663 (25%), Positives = 301/663 (45%), Gaps = 45/663 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+K+ +   V+EGS   L C L + P   + W  K   +         ++ D  ++  
Sbjct: 2319 PFFTKELRDLEVEEGSSASLRCEL-SKPGASVQW--KKNRMPLRAGGKFEMKQDGCLF-- 2373

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L++ ++     G+Y+  A + E  +SL  V ++      PP  I+ L+S+   +G+++ 
Sbjct: 2374 QLQMKDLVPEDSGSYSCHADSAE-TSSLVSVKEL------PPFFIDCLQSVTAHEGDTLS 2426

Query: 754  LSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            L  ++   P   + W K NK V    +    K +G    ++I +    +D G Y+  A  
Sbjct: 2427 LKCEL-SKPGVAVQW-KRNKVVLRSNRKYELKQEGCLLQLSI-RGLTPEDHGSYSCHA-- 2481

Query: 810  SEGIAETSAVITVE--------EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
              G AET+A++TV+         PTE    PP F    Q + V+E G   L   V   P 
Sbjct: 2482 --GSAETAALVTVKVRDTATIFSPTEL---PPFFKEELQSLEVEEGGAASLSC-VLSKPG 2535

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             S+ W +N  ++  S       DG  ++L I  +  E D+G Y C     AG +   A V
Sbjct: 2536 VSVRWKKNKLVLRSSRKYEMKQDGCLLQLQIKGLKPE-DAGSYSC----HAGDAETTAMV 2590

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980
             +      F K+L  + E EEG    L C+ S   VS +W  N   +      E+ Q+G 
Sbjct: 2591 AVTEVPPFFKKNLI-NVEAEEGGVASLCCELSKPGVSVQWKKNGVPLRAGSKYEMKQDGC 2649

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                        D G   C  +  ETS +L VKE    F   LQ  E +E     L  E+
Sbjct: 2650 LMQLQVSDLTPEDTGGYSCQAEMSETSAVLKVKEHATFFSSDLQSVEAEESGAVTLCCEL 2709

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            + S  + V W+++G  ++  + KY+ ++ G + +L+I++ +  D G YSC   +   +A 
Sbjct: 2710 SKSGVSGVQWKKNGVPLRVSR-KYEMKQDGRLLQLHIKDLTPEDSGGYSCSAGNAKTSAN 2768

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            + V ELPP     L++ +V +G+ A+   +L+K  A V+W K+   ++     ++  DG 
Sbjct: 2769 LVVRELPPIFKMSLESVEVEEGSSASLRCQLSKPGASVQWKKNRMPLRADGKYEMKQDGC 2828

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
              +L++ D   +D+G YSC  G++  +A + V+E +  F   L + +       A L  E
Sbjct: 2829 LIQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITEL-QSVEAEEGGAASLCCE 2887

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +    + V W K +  +  + ++ +  +     L I++   +D   +TC    A+++  +
Sbjct: 2888 LSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHIQELRPEDGGVFTCQTESAETSASV 2947

Query: 1280 KVE 1282
             V+
Sbjct: 2948 TVK 2950



 Score =  184 bits (449), Expect = 2e-44
 Identities = 185/742 (24%), Positives = 322/742 (43%), Gaps = 45/742 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP F    ++    EG  + L+C L    +P +A  +K  ++V   N    ++ +  + 
Sbjct: 2406 LPPFFIDCLQSVTAHEGDTLSLKCEL---SKPGVAVQWKRNKVVLRSNRKYELKQEGCLL 2462

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK----IKTGEKEPPQVIEPLKSMIVR 747
               L I  +     G+Y+  A + E  A + + ++    I +  + PP   E L+S+ V 
Sbjct: 2463 --QLSIRGLTPEDHGSYSCHAGSAETAALVTVKVRDTATIFSPTELPPFFKEELQSLEVE 2520

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G +  LS  V+  P  ++ W KN   +++      K DG    + I K  K +D G Y+
Sbjct: 2521 EGGAASLSC-VLSKPGVSVRWKKNKLVLRSSRKYEMKQDGCLLQLQI-KGLKPEDAGSYS 2578

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A    G AET+A++ V E       PP F      +  +E G   L   +++ P  S+
Sbjct: 2579 CHA----GDAETTAMVAVTEV------PPFFKKNLINVEAEEGGVASLCCELSK-PGVSV 2627

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W +N   +          DG  ++L ++++  E D+G Y C A  S  ++S   +V   
Sbjct: 2628 QWKKNGVPLRAGSKYEMKQDGCLMQLQVSDLTPE-DTGGYSCQAEMS--ETSAVLKVK-- 2682

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VS-TKWYHNKKEISGMDHREIIQEGRXX 982
             E  TF     +S E EE   V L C+ S + VS  +W  N   +      E+ Q+GR  
Sbjct: 2683 -EHATFFSSDLQSVEAEESGAVTLCCELSKSGVSGVQWKKNGVPLRVSRKYEMKQDGRLL 2741

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C   + +TS  LVV+E  P F   L+  EV+E   A L  +++ 
Sbjct: 2742 QLHIKDLTPEDSGGYSCSAGNAKTSANLVVRELPPIFKMSLESVEVEEGSSASLRCQLSK 2801

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
              A V W+++   ++    KY+ ++ G + +L +++    D G YSC       +A V V
Sbjct: 2802 PGASVQWKKNRMPLRAD-GKYEMKQDGCLIQLQMKDLQPEDSGSYSCHAGSAVTSATVAV 2860

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
             EL P  IT LQ+ +  +G  A+   EL+K    V+W K+   ++ S+  ++  +G   +
Sbjct: 2861 KELAPFFITELQSVEAEEGGAASLCCELSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQ 2920

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            L I +   +D G ++C+  +++ +A +TV+E   N      + +       A L  E+  
Sbjct: 2921 LHIQELRPEDGGVFTCQTESAETSASVTVKE---NL-----QSVKAEEGAAASLCCELSK 2972

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
                V W K +  +    +F +  D     L ++    +D   Y+C    AK++  L V 
Sbjct: 2973 PGASVQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKLEDSGSYSCHAGKAKTSATLAVR 3032

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
              E P       +   ++ GS  +L       P  + +W  N   ++  +  +   D   
Sbjct: 3033 --ELPLFFTRSLQRVEVEEGSSASLRCQLSK-PGVSVQWKKNRMPLRAGRKYEMKQDGCL 3089

Query: 1343 ASLTIKKVENTDAGIYKLRLEN 1364
              L IK V + D+G Y     N
Sbjct: 3090 FELRIKDVLSEDSGSYTCHAGN 3111



 Score =  181 bits (441), Expect = 2e-43
 Identities = 175/751 (23%), Positives = 314/751 (41%), Gaps = 44/751 (5%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +  +P TF +K K   ++EG+  +  C L    +  + W+  G+ ++         + D 
Sbjct: 1035 ITAVPVTFKQKMKNVQIEEGNVAIFRCELSKAGQ-SVEWMKGGDAVIRGGEKYQMRQRDT 1093

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
             +    L+I++VK      YT +  N E  A+L +          P    + LK++ V +
Sbjct: 1094 LLE---LRISDVKPDDSDIYTCICANIETTATLTV-------HALPVTFKQKLKNVHVEE 1143

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G S+ L  ++   P   + W +    ++       K       +TI +    +D GVYT 
Sbjct: 1144 GNSLTLYCEI-SKPGIPVEWRRGGDLLENGDKYQIKQREMALELTI-RDVDPEDSGVYTC 1201

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
               +      T A + V       A P  F    +    +E  ++ L   +++  V  + 
Sbjct: 1202 VCRDQR----TKATVKVV------AVPASFKVSLKSQDAEEGTSVSLCCELSKKGV-HVQ 1250

Query: 866  WYRN----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            W R+    +E +SP +      +G+  +L I  V  E D+G Y CVA    G     A V
Sbjct: 1251 WKRDAQPLSEEMSPGK-YQMKVEGKTAQLTIHGVQPE-DAGRYSCVA----GDEKTTAEV 1304

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGR 980
             +    V F + +Q S   +EG   +L  + S   S  +W   +  +      E+ QEG 
Sbjct: 1305 RVKALPVAFKRDIQ-SVAVKEGDRGVLCGELSRPGSQAEWRKGRVVLKPGRKYEMKQEGC 1363

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                        D G   C   + +++  L V    P F   L + EV E +  IL  E+
Sbjct: 1364 LVKLVINHVEESDAGKYTCKTNNSQSTAELTVHGLPPTFRLPLVNQEVMEGNSVILHCEL 1423

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
            +  ++ V W R G+++    +KY   K+    ++ I +  V D GEYSC+  +++  A +
Sbjct: 1424 SKASSWVEW-RKGKVLLKHGDKYQVRKKELQVEMKILDLGVSDGGEYSCVCGEQTTRATI 1482

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
            TV E P + +  L+N +V +GN+     E++K  A V W K    +      Q+   G  
Sbjct: 1483 TVKERPIKFLQELKNVQVQEGNEVKLRCEISKAGASVEWKKGEKVLSDGEKYQMKQSGSI 1542

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
             +L I  C  +D+G YSC     + TA + +    I F  +L    +V   +   L  E+
Sbjct: 1543 LELVIRKCQPEDSGTYSCVCAEVRSTATIIITAIPITFKQKLRNQEVVEEGS-VTLRCEL 1601

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
                + V W K+  ++++ EK+ +  + +   + IR  T  D  EY C +  A ++ ++K
Sbjct: 1602 SKAGVPVEWRKEAQLLKEGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIK 1661

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V  +   P     E E  + +  D        + P    +W     I+K     +  ++ 
Sbjct: 1662 VRAL---PVTFKQEMENLVVKEGDSGEFCCELSKPGAPVDWRKGRVILKPGYKYEMKLEG 1718

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
            +   L I  +E +DAG Y  +  ++   A++
Sbjct: 1719 RLNKLIINNIEESDAGKYTCKSSDSQSTAEL 1749



 Score =  173 bits (422), Expect = 3e-41
 Identities = 151/654 (23%), Positives = 285/654 (43%), Gaps = 34/654 (5%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +P +F    K+Q  +EG+ + L C L +     + W  +  + + +E      +  +   
Sbjct: 1217 VPASFKVSLKSQDAEEGTSVSLCCEL-SKKGVHVQWK-RDAQPLSEEMSPGKYQMKVEGK 1274

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L I  V+    G Y+ VA    G+      +++K     P      ++S+ V++G+ 
Sbjct: 1275 TAQLTIHGVQPEDAGRYSCVA----GDEKTTAEVRVKA---LPVAFKRDIQSVAVKEGDR 1327

Query: 752  VILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
             +L  ++   P     W K     KP +    K +G    + I   ++  D G YT K  
Sbjct: 1328 GVLCGEL-SRPGSQAEWRKGRVVLKPGRKYEMKQEGCLVKLVINHVEE-SDAGKYTCKTN 1385

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            NS+  AE    +TV      +  PP F        V E  ++ L   +++     + W +
Sbjct: 1386 NSQSTAE----LTV------HGLPPTFRLPLVNQEVMEGNSVILHCELSKAS-SWVEWRK 1434

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
               ++   +          +E+ I ++    D G+Y CV     G+ +  A +T+    +
Sbjct: 1435 GKVLLKHGDKYQVRKKELQVEMKILDLGVS-DGGEYSCVC----GEQTTRATITVKERPI 1489

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             F++ L K+ + +EG  V L C+ S    S +W   +K +S  +  ++ Q G        
Sbjct: 1490 KFLQEL-KNVQVQEGNEVKLRCEISKAGASVEWKKGEKVLSDGEKYQMKQSGSILELVIR 1548

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D G   C+  +  ++  +++      F +KL++ EV E+    L  E++     V
Sbjct: 1549 KCQPEDSGTYSCVCAEVRSTATIIITAIPITFKQKLRNQEVVEEGSVTLRCELSKAGVPV 1608

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W ++ +++K +  KY   + G   ++ IR  ++ D GEY+C +   + +AE+ V  LP 
Sbjct: 1609 EWRKEAQLLK-EGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPV 1667

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
                 ++N  V +G+   F  EL+K  A V W K    ++     ++ ++G+  KL I +
Sbjct: 1668 TFKQEMENLVVKEGDSGEFCCELSKPGAPVDWRKGRVILKPGYKYEMKLEGRLNKLIINN 1727

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
             +  DAG+Y+C+  +S+ TA LTV  P + F  +L     V       L+ E+    L V
Sbjct: 1728 IEESDAGKYTCKSSDSQSTAELTVRAPPVTFKTKL-RSQQVEEEKSVTLSCELSKPGLGV 1786

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
             W K +  ++++ K+ + +      L I+     D   Y+C   D K+T  + V
Sbjct: 1787 EWKKGQEQLQNSFKYQIRNRQGIMELTIKNTQLVDSGLYSCNYGDVKTTADITV 1840



 Score =  169 bits (410), Expect = 1e-39
 Identities = 240/1185 (20%), Positives = 450/1185 (37%), Gaps = 103/1185 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E + +   F  +L+     + + V  EC+    P  ++TW +    ++ S+ + +     
Sbjct: 551  EIRELQHTFARELKDSRAEEKAKVTLECETRR-PAKRVTWLKGMVELRSSRKY-VIRQKG 608

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
             V +L I  +   D+  + C      G   S  +L V+                      
Sbjct: 609  AVLSLTINSLEKSDSDIYIC----DVGTMQSRAQLTVQGETWSSSGWTLCCYGRLCKSSR 664

Query: 624  XXADILEGIPPTFSKKPKAQYVDE--------GSDILLECRLVAIPEPDIAWLFKGEEIV 675
               D     P  F    K   +DE        G  +   CR+      ++ W      + 
Sbjct: 665  NDKDCFIFFPRMFPSGQKVFILDELEDVECLEGDTVTFRCRICPSDYSEVKWYLDETLLY 724

Query: 676  PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735
             ++   + + +  +    VL    + +   GT +  A ++   ASL +        +  P
Sbjct: 725  TNDLNEIQLLAGGY---HVLTFRQLARKDTGTISFSAGDKRSYASLLV-------RERRP 774

Query: 736  QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITI 791
             +I+ L+     +G  ++LS  V   P   I W K+        +   ++S G    +TI
Sbjct: 775  TIIKALEDCEAIEGGGLVLSC-VTSKPCH-IRWYKDGCLMWNSSRYFASRS-GCEARLTI 831

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
             +     D GVY    E S G   T AV+TV+      A P  F    + +  +E  TI 
Sbjct: 832  REVGS-NDAGVY----ECSAGSVTTRAVVTVK------AIPAEFTQTLKTVEAREGETIT 880

Query: 852  LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
            L    +  P     W +  E I P +          I L I  +  E DSG+Y C   + 
Sbjct: 881  LTCEYSL-PGVHFHWNKGYESIRPGDRYIMRQRKTVISLTIKTLQPE-DSGEYTCQCRDH 938

Query: 912  AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGM 970
               +S    + +     TF + L K+ + +EG  V+L C+ S   +  +W   ++ +   
Sbjct: 939  RTTAS----LKVQAIPTTFTQQL-KNIQAQEGTNVVLRCELSKPGIPVEWRKGEELLKNG 993

Query: 971  DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
               ++ +               D GV  C+   Q+++  + +      F +K+++ +++E
Sbjct: 994  VRFQMRRRETTLELLIWKPVPEDSGVYSCVCGHQKSTATVRITAVPVTFKQKMKNVQIEE 1053

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
             +VAI   E++     V W + G+ +     KY   +R  + +L I +    D   Y+CI
Sbjct: 1054 GNVAIFRCELSKAGQSVEWMKGGDAVIRGGEKYQMRQRDTLLELRISDVKPDDSDIYTCI 1113

Query: 1091 LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150
              +   TA +TV  LP     +L+N  V +GN  T   E++K    V W + G  ++  +
Sbjct: 1114 CANIETTATLTVHALPVTFKQKLKNVHVEEGNSLTLYCEISKPGIPVEWRRGGDLLENGD 1173

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
              Q+       +L I D D +D+G Y+C   + +  A + V     +F + L        
Sbjct: 1174 KYQIKQREMALELTIRDVDPEDSGVYTCVCRDQRTKATVKVVAVPASFKVSLKSQD-AEE 1232

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIED---TEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
             T   L  E+  + + V W +    + +     K+ +  + K   L I     +D   Y+
Sbjct: 1233 GTSVSLCCELSKKGVHVQWKRDAQPLSEEMSPGKYQMKVEGKTAQLTIHGVQPEDAGRYS 1292

Query: 1268 CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            CV  D K+T +++V+ +  P       +   +K G D  +L    + P    EW     +
Sbjct: 1293 CVAGDEKTTAEVRVKAL--PVAFKRDIQSVAVKEG-DRGVLCGELSRPGSQAEWRKGRVV 1349

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +K  +  +   +     L I  VE +DAG Y  +  N+   A++ ++          G P
Sbjct: 1350 LKPGRKYEMKQEGCLVKLVINHVEESDAGKYTCKTNNSQSTAELTVH----------GLP 1399

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
                +   +  +        GNS I++  +  +     EW   K + K     Q  K   
Sbjct: 1400 PTFRLPLVNQEVM------EGNSVILHCELS-KASSWVEWRKGKVLLKHGDKYQVRKKEL 1452

Query: 1448 SYRFRAYAVNEVDISDAS-----ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
                +   +   D  + S     +TT     +KE  I+     + LKN+  +   +++L 
Sbjct: 1453 QVEMKILDLGVSDGGEYSCVCGEQTTRATITVKERPIK---FLQELKNVQVQEGNEVKLR 1509

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX-----XXXXXYKCIAFNDHG 1557
            C         V W + G+K+ +    Y+ +                    Y C+      
Sbjct: 1510 CEISKA-GASVEW-KKGEKVLSDGEKYQMKQSGSILELVIRKCQPEDSGTYSCVC----A 1563

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE----GIPPPEVIWYKNGNKL 1613
            EV ++  + I   P IT   +   +  +V +E  VT   E    G+P   V W K    L
Sbjct: 1564 EVRSTATIIITAIP-ITFKQK--LRNQEVVEEGSVTLRCELSKAGVP---VEWRKEAQLL 1617

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            +  ++Y +  + + + + I+ +  +   +Y    +  A ++ ++V
Sbjct: 1618 KEGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKV 1662



 Score =  164 bits (398), Expect = 3e-38
 Identities = 156/578 (26%), Positives = 244/578 (42%), Gaps = 42/578 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESD 687
            ++ +P  F +  ++  V EG   +L C  ++ P     W  KG  ++ P     +  E  
Sbjct: 1306 VKALPVAFKRDIQSVAVKEGDRGVL-CGELSRPGSQAEWR-KGRVVLKPGRKYEMKQEG- 1362

Query: 688  MHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                C V L I +V++   G YT    N +  A L +          PP    PL +  V
Sbjct: 1363 ----CLVKLVINHVEESDAGKYTCKTNNSQSTAELTV-------HGLPPTFRLPLVNQEV 1411

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVY 803
             +G SVIL  ++       + W K    +K       GD + +    +    K+ D GV 
Sbjct: 1412 MEGNSVILHCEL-SKASSWVEWRKGKVLLK------HGDKYQVRKKELQVEMKILDLGVS 1464

Query: 804  TLKAENSE-GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
                 +   G   T A ITV+E       P  F+   + + V+E   +KL   +++    
Sbjct: 1465 DGGEYSCVCGEQTTRATITVKE------RPIKFLQELKNVQVQEGNEVKLRCEISKAGA- 1517

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            S+ W +  +++S  E       G  +ELVI     E DSG Y CV +         A + 
Sbjct: 1518 SVEWKKGEKVLSDGEKYQMKQSGSILELVIRKCQPE-DSGTYSCVCAEVRST----ATII 1572

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
            I    +TF + L+     EEG +V L C+ S   V  +W    + +   +  ++ QEGR 
Sbjct: 1573 ITAIPITFKQKLRNQEVVEEG-SVTLRCELSKAGVPVEWRKEAQLLKEGEKYQMRQEGRA 1631

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G   C V    TS  + V+     F +++++  VKE D      E++
Sbjct: 1632 AEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPVTFKQEMENLVVKEGDSGEFCCELS 1691

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
               A V W +   I+KP   KY+ +  G + KL I N    D G+Y+C   D   TAE+T
Sbjct: 1692 KPGAPVDWRKGRVILKPGY-KYEMKLEGRLNKLIINNIEESDAGKYTCKSSDSQSTAELT 1750

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V   P    T+L++Q+V +    T   EL+K    V W K   ++Q S   Q+       
Sbjct: 1751 VRAPPVTFKTKLRSQQVEEEKSVTLSCELSKPGLGVEWKKGQEQLQNSFKYQIRNRQGIM 1810

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199
            +L I +  L D+G YSC  G+ K TA +TV      +T
Sbjct: 1811 ELTIKNTQLVDSGLYSCNYGDVKTTADITVTRKGDPYT 1848



 Score =  152 bits (369), Expect = 9e-35
 Identities = 149/604 (24%), Positives = 254/604 (42%), Gaps = 43/604 (7%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP F K       +EG    L C L + P   + W   G  +       +  +  +   
Sbjct: 2595 VPPFFKKNLINVEAEEGGVASLCCEL-SKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQ- 2652

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L+++++     G Y+  A   E  A    VLK+K   +        L+S+   +  +
Sbjct: 2653 ---LQVSDLTPEDTGGYSCQAEMSETSA----VLKVK---EHATFFSSDLQSVEAEESGA 2702

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V L  ++  +    + W KN  P++       K DG    + I K    +D G Y+  A 
Sbjct: 2703 VTLCCELSKSGVSGVQWKKNGVPLRVSRKYEMKQDGRLLQLHI-KDLTPEDSGGYSCSAG 2761

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N    A+TSA + V E       PP+F    + + V+E  +  L  ++++ P  S+ W +
Sbjct: 2762 N----AKTSANLVVREL------PPIFKMSLESVEVEEGSSASLRCQLSK-PGASVQWKK 2810

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            N   +          DG  I+L + ++  E DSG Y C     AG +   A V +     
Sbjct: 2811 NRMPLRADGKYEMKQDGCLIQLQMKDLQPE-DSGSYSC----HAGSAVTSATVAVKELAP 2865

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             F+  LQ S E EEG    L C+ S   V  +W  N+  + G    E+ QEG        
Sbjct: 2866 FFITELQ-SVEAEEGGAASLCCELSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHIQ 2924

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D GV  C  +  ETS  + VKE        LQ  + +E   A L  E++   A V
Sbjct: 2925 ELRPEDGGVFTCQTESAETSASVTVKEN-------LQSVKAEEGAAASLCCELSKPGASV 2977

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W+++ E+      +++ ++ G + +L +++  + D G YSC       +A + V ELP 
Sbjct: 2978 QWKKN-EVALRAGGRFEMKQDGCLIQLQVKDLKLEDSGSYSCHAGKAKTSATLAVRELPL 3036

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
                 LQ  +V +G+ A+   +L+K    V+W K+   ++     ++  DG   +L+I D
Sbjct: 3037 FFTRSLQRVEVEEGSSASLRCQLSKPGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKD 3096

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
               +D+G Y+C  GN++ +  + V+     F   L + +         L  ++    + V
Sbjct: 3097 VLSEDSGSYTCHAGNAETSGAVEVKALPTLFITEL-QSVEAEEGGSVSLCCQLSKPGVSV 3155

Query: 1228 TWYK 1231
             W K
Sbjct: 3156 QWKK 3159



 Score =  148 bits (358), Expect = 2e-33
 Identities = 145/571 (25%), Positives = 243/571 (42%), Gaps = 47/571 (8%)

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNN 870
            G + ++A +TV+E   + + P       ++I  KE  +++L      NP P +  W++  
Sbjct: 79   GKSRSTAQLTVKERPLQVSHP------LEDIDAKENSSVQLSCGF--NPSPRVVRWFKGR 130

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +  S   +   +G   EL I  +   +DSG Y+CVA    G +   A + ++V  +  
Sbjct: 131  TALKTSNKYSMRREGYRAELTIHGLTG-MDSGQYRCVA----GGAQSTAHLQVEVRTLKL 185

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEI-SGMDHREIIQEGRXXXXXXXX 988
            V+HL+   + EE  +    C+ +  ++  +W  N   + S   +R  IQ           
Sbjct: 186  VRHLEP-VDVEEDGSATFSCELNFVIANAEWLLNNVRLYSNAVNR--IQHMGTMHSLTIK 242

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
                 VG +         S  L VKE    F++ L+D   +E+    L  EI+ ETA  V
Sbjct: 243  KLRPQVGRVTFKAGLLSESAPLKVKERPAVFLKSLEDAVGEEEGEVCLHCEISKETATPV 302

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV----- 1103
            W +DG ++    +K++F + G  R L IR+ S  D G Y+C        A+VTV      
Sbjct: 303  WRKDGSVLTAD-DKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLE 361

Query: 1104 -------------ELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFS 1149
                         +L   I+ RL+   V +G   TFE  L+   D    W  +G  +   
Sbjct: 362  NSSFACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATD 421

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
            + +Q   +G K +L I +  L D+G+    + +  C  +L V+E  ++    L     VP
Sbjct: 422  SRLQAIGNGCKYRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVP 481

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
               DA L+ EI    + + W K   +I  + K+ +        L+IR  T  D  +Y C 
Sbjct: 482  GE-DAELSCEITKTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCE 540

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
                 S  + KVE+ E         ++ R +  + VTL  + +  P     W+     ++
Sbjct: 541  ADGVAS--RAKVEIRELQHTFARELKDSRAEEKAKVTLECETRR-PAKRVTWLKGMVELR 597

Query: 1330 KCKHTKPSIDSKSA--SLTIKKVENTDAGIY 1358
              +  K  I  K A  SLTI  +E +D+ IY
Sbjct: 598  SSR--KYVIRQKGAVLSLTINSLEKSDSDIY 626



 Score =  125 bits (301), Expect = 2e-26
 Identities = 127/516 (24%), Positives = 213/516 (41%), Gaps = 42/516 (8%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            FS   ++   +E   + L C L       + W   G  +     +S   E         L
Sbjct: 2688 FSSDLQSVEAEESGAVTLCCELSKSGVSGVQWKKNGVPL----RVSRKYEMKQDGRLLQL 2743

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             I ++     G Y+  A N +  A+L +        + PP     L+S+ V +G S  L 
Sbjct: 2744 HIKDLTPEDSGGYSCSAGNAKTSANLVV-------RELPPIFKMSLESVEVEEGSSASLR 2796

Query: 756  AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             Q+   P  ++ W KN  P++A      K DG    +  +K  + +D G Y+  A    G
Sbjct: 2797 CQL-SKPGASVQWKKNRMPLRADGKYEMKQDGCLIQLQ-MKDLQPEDSGSYSCHA----G 2850

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
             A TSA + V+E        P FI   Q +  +E G   L   +++ P   + W +N   
Sbjct: 2851 SAVTSATVAVKELA------PFFITELQSVEAEEGGAASLCCELSK-PGVKVQWKKNRIP 2903

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +  S       +G  ++L I  +  E D G + C   ++   +S           VT  +
Sbjct: 2904 LRGSSRYEMKQEGCLLQLHIQELRPE-DGGVFTCQTESAETSAS-----------VTVKE 2951

Query: 933  HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            +LQ S + EEG    L C+ S    S +W  N+  +      E+ Q+G            
Sbjct: 2952 NLQ-SVKAEEGAAASLCCELSKPGASVQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKL 3010

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D G   C     +TS  L V+E    F R LQ  EV+E   A L  +++     V W++
Sbjct: 3011 EDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQRVEVEEGSSASLRCQLSKPGVSVQWKK 3070

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
            +   ++  + KY+ ++ G + +L I++    D G Y+C   +   +  V V  LP   IT
Sbjct: 3071 NRMPLRAGR-KYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAETSGAVEVKALPTLFIT 3129

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ 1147
             LQ+ +  +G   +   +L+K    V+W K+G  ++
Sbjct: 3130 ELQSVEAEEGGSVSLCCQLSKPGVSVQWKKNGMPLR 3165



 Score =  120 bits (289), Expect = 4e-25
 Identities = 136/571 (23%), Positives = 231/571 (40%), Gaps = 60/571 (10%)

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDMHMYCSVLKITNVKKFQE 705
            E S + L C     P P +   FKG   +   N  S+  E     Y + L I  +     
Sbjct: 107  ENSSVQLSCGFN--PSPRVVRWFKGRTALKTSNKYSMRREG----YRAELTIHGLTGMDS 160

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ---VVGNP 762
            G Y  VA   +  A L +       E    +++  L+ + V +  S   S +   V+ N 
Sbjct: 161  GQYRCVAGGAQSTAHLQV-------EVRTLKLVRHLEPVDVEEDGSATFSCELNFVIANA 213

Query: 763  RPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSA 818
                 W  NN  + +      +  G  HS+TI   KK++ + G  T KA    G+   SA
Sbjct: 214  E----WLLNNVRLYSNAVNRIQHMGTMHSLTI---KKLRPQVGRVTFKA----GLLSESA 262

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             + V+E       P +F+   ++   +E+G + L   +++     + W ++  +++  + 
Sbjct: 263  PLKVKE------RPAVFLKSLEDAVGEEEGEVCLHCEISKETATPV-WRKDGSVLTADDK 315

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---------------HGARVTI 923
                  G+   L+I ++  + D+G Y C    S  K+                 G+    
Sbjct: 316  HEFLQFGKARALIIRSLSKD-DAGLYTCDFGTSQTKAKVTVHGECLENSSFACRGSGTKR 374

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRX 981
            D+  +T V+ L K+    EG+T   EC  SH+V  +  W  N + ++     + I  G  
Sbjct: 375  DLH-ITIVQRL-KTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATDSRLQAIGNGCK 432

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G +   +KD    T+L VKE      R L + +    + A L  EI 
Sbjct: 433  YRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVPGEDAELSCEIT 492

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
                 + W +DG +I+ +  KY+     ++ KL IRN ++ D G+Y C     +  A+V 
Sbjct: 493  KTDVTIRWLKDGRLIR-QSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGVASRAKVE 551

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            + EL       L++ +  +  K T E E  +    V W K   E++ S    +   G   
Sbjct: 552  IRELQHTFARELKDSRAEEKAKVTLECETRRPAKRVTWLKGMVELRSSRKYVIRQKGAVL 611

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             L I   +  D+  Y C+VG  +  A LTV+
Sbjct: 612  SLTINSLEKSDSDIYICDVGTMQSRAQLTVQ 642



 Score =  115 bits (277), Expect = 1e-23
 Identities = 136/639 (21%), Positives = 238/639 (37%), Gaps = 56/639 (8%)

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
            W   GE + P   +++  +  +H  C    +T+ +    G    VA      A L +   
Sbjct: 37   WTLNGEVLEPSAAVNIDRKGTVHSLC----LTSTESSMCGPVVFVAGKSRSTAQLTV--- 89

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783
                ++ P QV  PL+ +  ++  SV LS     +PR  + W K    +K       + +
Sbjct: 90   ----KERPLQVSHPLEDIDAKENSSVQLSCGFNPSPR-VVRWFKGRTALKTSNKYSMRRE 144

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
            G    +TI     + D G Y   A    G A+++A + VE  T +       +   + + 
Sbjct: 145  GYRAELTIHGLTGM-DSGQYRCVA----GGAQSTAHLQVEVRTLK------LVRHLEPVD 193

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
            V+E G+      +    + +  W  NN  +  +        G    L I  +  ++    
Sbjct: 194  VEEDGSATFSCELNF-VIANAEWLLNNVRLYSNAVNRIQHMGTMHSLTIKKLRPQVGRVT 252

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYH 962
            +K      AG  S  A + +      F+K L+ +   EEG+ V L C+ S   +T  W  
Sbjct: 253  FK------AGLLSESAPLKVKERPAVFLKSLEDAVGEEEGE-VCLHCEISKETATPVWRK 305

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---- 1018
            +   ++  D  E +Q G+            D G+  C     +T   + V     E    
Sbjct: 306  DGSVLTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLENSSF 365

Query: 1019 --------------FIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKY 1063
                           +++L+   V E +    E  ++    D   W  +G+++    ++ 
Sbjct: 366  ACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATD-SRL 424

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
                 G   +L I+   + D G+    ++D +C   + V E P  I   L N K   G  
Sbjct: 425  QAIGNGCKYRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVPGED 484

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            A    E+TK D  +RW KDG  I+ S   ++ +     KL I +  + D+G+Y CE    
Sbjct: 485  AELSCEITKTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGV 544

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
               A + + E    F   L +           L  E       VTW K    +  + K+ 
Sbjct: 545  ASRAKVEIRELQHTFARELKD-SRAEEKAKVTLECETRRPAKRVTWLKGMVELRSSRKYV 603

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            +       +L I    + D   Y C +   +S  +L V+
Sbjct: 604  IRQKGAVLSLTINSLEKSDSDIYICDVGTMQSRAQLTVQ 642



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 105/431 (24%), Positives = 181/431 (41%), Gaps = 44/431 (10%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++  +PP F    ++  V+EGS   L C+L + P   + W      +  D    +  +  
Sbjct: 2770 VVRELPPIFKMSLESVEVEEGSSASLRCQL-SKPGASVQWKKNRMPLRADGKYEMKQDG- 2827

Query: 688  MHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                C + L++ +++    G+Y+  A    G A     + +K   +  P  I  L+S+  
Sbjct: 2828 ----CLIQLQMKDLQPEDSGSYSCHA----GSAVTSATVAVK---ELAPFFITELQSVEA 2876

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVY 803
             +G +  L  + +  P   + W KN  P++       K +G    + I +  + +D GV+
Sbjct: 2877 EEGGAASLCCE-LSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHI-QELRPEDGGVF 2934

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            T + E+    AETSA +TV+E               Q +  +E     L   +++ P  S
Sbjct: 2935 TCQTES----AETSASVTVKE-------------NLQSVKAEEGAAASLCCELSK-PGAS 2976

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + W +N   +          DG  I+L + ++  E DSG Y C     AGK+   A + +
Sbjct: 2977 VQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKLE-DSGSYSC----HAGKAKTSATLAV 3031

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982
                + F + LQ+  E EEG +  L CQ S   VS +W  N+  +      E+ Q+G   
Sbjct: 3032 RELPLFFTRSLQR-VEVEEGSSASLRCQLSKPGVSVQWKKNRMPLRAGRKYEMKQDGCLF 3090

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C   + ETS  + VK     FI +LQ  E +E     L  +++ 
Sbjct: 3091 ELRIKDVLSEDSGSYTCHAGNAETSGAVEVKALPTLFITELQSVEAEEGGSVSLCCQLSK 3150

Query: 1043 ETADVVWERDG 1053
                V W+++G
Sbjct: 3151 PGVSVQWKKNG 3161



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 112/532 (21%), Positives = 204/532 (38%), Gaps = 40/532 (7%)

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W  N E++ PS  +  +  G    L +T+ +S +  G    VA    GKS   A++T+  
Sbjct: 37   WTLNGEVLEPSAAVNIDRKGTVHSLCLTSTESSM-CGPVVFVA----GKSRSTAQLTVK- 90

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984
            E+   V H  +  + +E  +V L C  + +    +W+  +  +   +   + +EG     
Sbjct: 91   ERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVRWFKGRTALKTSNKYSMRREGYRAEL 150

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G  +C+    +++  L V+    + +R L+  +V+E   A    E+N   
Sbjct: 151  TIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKLVRHLEPVDVEEDGSATFSCELNFVI 210

Query: 1045 ADVVWERDGEIIKPKKNKYD-FEKRGHIRKLYIRNTSVH-DEGEYSCILRDESCTAEVTV 1102
            A+  W  +   ++   N  +  +  G +  L I+          +   L  ES  A + V
Sbjct: 211  ANAEWLLNN--VRLYSNAVNRIQHMGTMHSLTIKKLRPQVGRVTFKAGLLSES--APLKV 266

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
             E P   +  L++    +  +     E++K  A   W KDGS +   +  +    GK + 
Sbjct: 267  KERPAVFLKSLEDAVGEEEGEVCLHCEISKETATPVWRKDGSVLTADDKHEFLQFGKARA 326

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTV-----EEPS-------------INFTLRLPE 1204
            L I     DDAG Y+C+ G S+  A +TV     E  S             I    RL  
Sbjct: 327  LIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLENSSFACRGSGTKRDLHITIVQRLKT 386

Query: 1205 FILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
              ++   T   + +L+  + D+     W     V+    +   I +  K  L I++    
Sbjct: 387  LSVLEGETCTFECHLSHSVDDQP---CWTINGQVVATDSRLQAIGNGCKYRLTIKEAQLS 443

Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            D  +    + D    T L V+  E P  I       +   G D  L  +          W
Sbjct: 444  DSGDVVFTIKDLACRTLLFVK--EKPVHIFRDLLNIKAVPGEDAELSCEITK-TDVTIRW 500

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
            + + ++I++    + ++    A L I+     D+G Y    +     A VE+
Sbjct: 501  LKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGVASRAKVEI 552



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 85/348 (24%), Positives = 133/348 (38%), Gaps = 9/348 (2%)

Query: 939  ETEEGKTVILECQTSHTVST--KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
            E  E +  + + +TS       +W  N + +       I ++G               G 
Sbjct: 14   EVMEPEAALFQVETSLRSGRPPRWTLNGEVLEPSAAVNIDRKGTVHSLCLTSTESSMCGP 73

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
            +  +     ++  L VKE   +    L+D + KE     L    N     V W +    +
Sbjct: 74   VVFVAGKSRSTAQLTVKERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVRWFKGRTAL 133

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
            K   NKY   + G+  +L I   +  D G+Y C+      TA + V     +++  L+  
Sbjct: 134  KTS-NKYSMRREGYRAELTIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKLVRHLEPV 192

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDDAGE 1175
             V +   ATF  EL    A   W  +   + +SN + ++   G    L I        G 
Sbjct: 193  DVEEDGSATFSCELNFVIANAEWLLNNVRL-YSNAVNRIQHMGTMHSLTIKKLR-PQVGR 250

Query: 1176 YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235
             + + G    +A L V+E    F L+  E  +     +  L  EI  ET    W K  SV
Sbjct: 251  VTFKAGLLSESAPLKVKERPAVF-LKSLEDAVGEEEGEVCLHCEISKETATPVWRKDGSV 309

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            +   +K   +   K R LIIR  ++DD   YTC      S TK KV V
Sbjct: 310  LTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDF--GTSQTKAKVTV 355



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 120/652 (18%), Positives = 236/652 (36%), Gaps = 30/652 (4%)

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
            +R +   EV E + A+ +VE +  +     W  +GE+++P     + +++G +  L + +
Sbjct: 7    VRGMSPVEVMEPEAALFQVETSLRSGRPPRWTLNGEVLEPSA-AVNIDRKGTVHSLCLTS 65

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138
            T     G    +      TA++TV E P ++   L++    + +             +VR
Sbjct: 66   TESSMCGPVVFVAGKSRSTAQLTVKERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVR 125

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF 1198
            WFK  + ++ SN   +  +G + +L I+     D+G+Y C  G ++ TA L VE  ++  
Sbjct: 126  WFKGRTALKTSNKYSMRREGYRAELTIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKL 185

Query: 1199 TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
               L E + V  +  A  + E+     +  W      +       +       +L I+K 
Sbjct: 186  VRHL-EPVDVEEDGSATFSCELNFVIANAEWLLNNVRLYSNAVNRIQHMGTMHSLTIKKL 244

Query: 1259 -TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
              +  +  +   LL   +  K+K     F   + D   E       +V L  +       
Sbjct: 245  RPQVGRVTFKAGLLSESAPLKVKERPAVFLKSLEDAVGE----EEGEVCLHCEISK-ETA 299

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               W  +  ++      +     K+ +L I+ +   DAG+Y      +   A V ++   
Sbjct: 300  TPVWRKDGSVLTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGEC 359

Query: 1378 LDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
            L+  S    G     ++  + +          G +      + +   D   W     +  
Sbjct: 360  LENSSFACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVA 419

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK-----VIKETKIQSPTVEKPLKN 1490
            T + +Q +     YR     + E  +SD+ +     K      +   K +   + + L N
Sbjct: 420  TDSRLQAIGNGCKYRL---TIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLN 476

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXX 1546
            I   P ED EL+C         + W +DG+ ++ +        +N               
Sbjct: 477  IKAVPGEDAELSCEITKT-DVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSG 535

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
             Y C A       +   +  +Q      + +   ++K KV  E          P   V W
Sbjct: 536  DYCCEADGVASRAKVE-IRELQHTFARELKDSRAEEKAKVTLECETRR-----PAKRVTW 589

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             K   +L + ++Y I  K     + I  L++S S  Y  +       + + V
Sbjct: 590  LKGMVELRSSRKYVIRQKGAVLSLTINSLEKSDSDIYICDVGTMQSRAQLTV 641



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 117/598 (19%), Positives = 210/598 (35%), Gaps = 48/598 (8%)

Query: 1109 IITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS--NHIQLTIDGKKQKLKI 1165
            I+  L++ +  +G+  TF   +   D + V+W+ D + +  +  N IQL + G    L  
Sbjct: 685  ILDELEDVECLEGDTVTFRCRICPSDYSEVKWYLDETLLYTNDLNEIQL-LAGGYHVLTF 743

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
                  D G  S   G+ +  A L V E        L +   +       +   +  +  
Sbjct: 744  RQLARKDTGTISFSAGDKRSYASLLVRERRPTIIKALEDCEAIEGG--GLVLSCVTSKPC 801

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
             + WYK   ++ ++ ++       +  L IR+   +D   Y C       TT+  V V  
Sbjct: 802  HIRWYKDGCLMWNSSRYFASRSGCEARLTIREVGSNDAGVYECSA--GSVTTRAVVTVKA 859

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
             P +     +    + G  +TL  +Y + P  +  W    + I+              SL
Sbjct: 860  IPAEFTQTLKTVEAREGETITLTCEY-SLPGVHFHWNKGYESIRPGDRYIMRQRKTVISL 918

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
            TIK ++  D+G Y       C   D     ++  +  P      L+      NI   E  
Sbjct: 919  TIKTLQPEDSGEY------TCQCRDHRTTASLKVQAIPTTFTQQLK------NIQAQE-- 964

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              G + ++   +    I   EW   + + K     Q  +  ++     +     D    S
Sbjct: 965  --GTNVVLRCELSKPGIPV-EWRKGEELLKNGVRFQMRRRETTLELLIWKPVPEDSGVYS 1021

Query: 1466 ETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
                + K     +I +   T ++ +KN+  E        C      Q  V W + G  + 
Sbjct: 1022 CVCGHQKSTATVRITAVPVTFKQKMKNVQIEEGNVAIFRCELSKAGQ-SVEWMKGGDAVI 1080

Query: 1524 TAKATYENRXXXXXXXXXXXX-----XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
                 Y+ R                    Y CI  N    +ET+  + +   PV     +
Sbjct: 1081 RGGEKYQMRQRDTLLELRISDVKPDDSDIYTCICAN----IETTATLTVHALPVTF--KQ 1134

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
             +K  H      L        P   V W + G+ LEN  +Y I  +E    + I+++   
Sbjct: 1135 KLKNVHVEEGNSLTLYCEISKPGIPVEWRRGGDLLENGDKYQIKQREMALELTIRDVDPE 1194

Query: 1639 HSSKYTIEASNTAGTSSVEV-----TLKVYDKPSKPE---GPVIMREISRESVTIEWK 1688
             S  YT    +    ++V+V     + KV  K    E      +  E+S++ V ++WK
Sbjct: 1195 DSGVYTCVCRDQRTKATVKVVAVPASFKVSLKSQDAEEGTSVSLCCELSKKGVHVQWK 1252



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 11/198 (5%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAII--- 550
            L   ++ +S+  +  P+F   L    T  G T++  C+V G P P ++WF+ Q++++   
Sbjct: 4344 LKELQQRSSQPTNTPPVFESLLSDWTTKIGQTIKLTCKVTGSPTPVVSWFKGQSSLLPLH 4403

Query: 551  -----KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN-AAGFASSTTELIVEAPL 604
                 + S  F +Y       + +  +V P D        ++      S T  LI+++  
Sbjct: 4404 CTCQPRSSVGFVLYMHSSFTHSYMC-DVRPLDGLPLEDDPRHIILADCSGTCTLILDSLS 4462

Query: 605  SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664
            +    +               A ++   PP F  + ++  + +G +I   C  +  P P 
Sbjct: 4463 AQDSGQYACFAHSFMGSAGTLAKVVVQAPPRFVSRLESACLIKGENIQFSCSTLTTPLPQ 4522

Query: 665  IAWLFKGEEIVPDENISV 682
            I W  +G E++  E   +
Sbjct: 4523 IRWSKEGRELIDMEKYCI 4540



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 49/184 (26%), Positives = 78/184 (42%), Gaps = 16/184 (8%)

Query: 1074 LYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE- 1129
            L + + S  D G+Y+C        + T    VV+ PP  ++RL++  + KG    F    
Sbjct: 4456 LILDSLSAQDSGQYACFAHSFMGSAGTLAKVVVQAPPRFVSRLESACLIKGENIQFSCST 4515

Query: 1130 LTKGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEV--GNSKC 1185
            LT     +RW K+G E+       +  D +     L +      D G+Y CE+      C
Sbjct: 4516 LTTPLPQIRWSKEGRELIDMEKYCIRNDARSGILSLTVIGATEADIGQYECELMWRTKTC 4575

Query: 1186 -TAILTVEEPSINFTLRLPEFILV-PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
             T +L V EP +     L E +L+ P  T +     +P  T  V   +    +ED E+  
Sbjct: 4576 RTYLLKVGEPDL-----LKEILLMDPFITQSSADQAVPASTGQVL-QQPPCFLEDEEEEI 4629

Query: 1244 LISD 1247
             IS+
Sbjct: 4630 YISE 4633



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 25/89 (28%), Positives = 50/89 (56%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            EL P  IT LQ+ +  +G  A+   EL++     +W K+   ++ ++  ++  +G   +L
Sbjct: 3167 ELAPFFITELQSVEAEEGGAASLCCELSRPAVKAQWKKNRIPLRANSRYEMKQEGCLLQL 3226

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             I +   +D G YSC+ G+++ +A L+V+
Sbjct: 3227 HIQELRPEDGGSYSCQAGSAETSARLSVK 3255



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 31/283 (10%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            I+  IP TF +K + Q V E   + L C L     P + W  + + +   E   +  E  
Sbjct: 1572 IITAIPITFKQKLRNQEVVEEGSVTLRCELSKAGVP-VEWRKEAQLLKEGEKYQMRQEG- 1629

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                 + + I  V     G Y          A + +     T ++E       +++++V+
Sbjct: 1630 ---RAAEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPVTFKQE-------MENLVVK 1679

Query: 748  QGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G+S     + +  P   + W K     KP      K +G  + + I+   +  D G YT
Sbjct: 1680 EGDSGEFCCE-LSKPGAPVDWRKGRVILKPGYKYEMKLEGRLNKL-IINNIEESDAGKYT 1737

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             K+ +S+  AE    +TV  P      P  F  + +   V+E+ ++ L   +++ P   +
Sbjct: 1738 CKSSDSQSTAE----LTVRAP------PVTFKTKLRSQQVEEEKSVTLSCELSK-PGLGV 1786

Query: 865  TWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDSGDYKC 906
             W +  E +  S +   +N  G  +EL I N    +DSG Y C
Sbjct: 1787 EWKKGQEQLQNSFKYQIRNRQG-IMELTIKNTQL-VDSGLYSC 1827



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 77/398 (19%), Positives = 148/398 (37%), Gaps = 43/398 (10%)

Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
           +F++ L      +   V   C++       + W R+   +  + D   +        L+I
Sbjct: 272 VFLKSLEDAVGEEEGEVCLHCEISKETATPV-W-RKDGSVLTADDKHEFLQFGKARALII 329

Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630
           R +  +DAG +TC       F +S T+    A ++ HG E                D+  
Sbjct: 330 RSLSKDDAGLYTC------DFGTSQTK----AKVTVHG-ECLENSSFACRGSGTKRDL-- 376

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
               T  ++ K   V EG     EC L    +    W   G+ +  D  +  AI +    
Sbjct: 377 --HITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATDSRLQ-AIGNGC-K 432

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
           Y   +K   +    +  +T+       + +   +L +K   ++P  +   L ++    GE
Sbjct: 433 YRLTIKEAQLSDSGDVVFTI------KDLACRTLLFVK---EKPVHIFRDLLNIKAVPGE 483

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAE 808
              LS ++      TI W K+ + ++  P        ++   +++   ++D G Y  +A 
Sbjct: 484 DAELSCEIT-KTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEA- 541

Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
             +G+A + A + + E          F    ++   +EK  + L    TR P   +TW +
Sbjct: 542 --DGVA-SRAKVEIRELQH------TFARELKDSRAEEKAKVTLECE-TRRPAKRVTWLK 591

Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
               +  S        G  + L I +++   DS  Y C
Sbjct: 592 GMVELRSSRKYVIRQKGAVLSLTINSLEKS-DSDIYIC 628



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 1/89 (1%)

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            E  P FI +LQ  E +E   A L  E++       W+++  I     ++Y+ ++ G + +
Sbjct: 3167 ELAPFFITELQSVEAEEGGAASLCCELSRPAVKAQWKKN-RIPLRANSRYEMKQEGCLLQ 3225

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            L+I+     D G YSC       +A ++V
Sbjct: 3226 LHIQELRPEDGGSYSCQAGSAETSARLSV 3254



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 2/116 (1%)

Query: 488  LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
            L+  +D    F K     + M P+F E  + +     ST+   C VEG     + W +  
Sbjct: 3771 LDTAVDVQAAF-KSYKTSKDMRPVFSEVFKNQSADLHSTLTLVCVVEGN-LSTVRWLKNG 3828

Query: 548  AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              I           +  V +LVI+ +   D+G +TC A N  G  S    + V  P
Sbjct: 3829 QSIMNDHRCCSETTETGVCSLVIKNLASTDSGVYTCEAVNKFGITSYNGNITVVQP 3884



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 6/77 (7%)

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTR 858
            YTL+  +S  + +TS +  ++E  + +++P    P+F +   + T K   TIKL  +VT 
Sbjct: 4327 YTLQGRSS--VVKTSWLKDLKELQQRSSQPTNTPPVFESLLSDWTTKIGQTIKLTCKVTG 4384

Query: 859  NPVPSITWYRNNEIISP 875
            +P P ++W++    + P
Sbjct: 4385 SPTPVVSWFKGQSSLLP 4401



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F +++      +G + +F C++   P   + W +   I+KP   ++M  +   +  L+I 
Sbjct: 1669 FKQEMENLVVKEGDSGEFCCELSK-PGAPVDWRKGRVILKPGYKYEMKLEG-RLNKLIIN 1726

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             +   DAG +TC + +    + ST EL V AP
Sbjct: 1727 NIEESDAGKYTCKSSD----SQSTAELTVRAP 1754



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELV 891
            P+F   F+  +     T+ LV  V  N + ++ W +N + I++     ++  +     LV
Sbjct: 3792 PVFSEVFKNQSADLHSTLTLVCVVEGN-LSTVRWLKNGQSIMNDHRCCSETTETGVCSLV 3850

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            I N+ S  DSG Y C A N  G +S+   +T+
Sbjct: 3851 IKNLAST-DSGVYTCEAVNKFGITSYNGNITV 3881



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 8/117 (6%)

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            IL     +D G Y   A +  G A T A + V+ P       P F++R +   + +   I
Sbjct: 4457 ILDSLSAQDSGQYACFAHSFMGSAGTLAKVVVQAP-------PRFVSRLESACLIKGENI 4509

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKC 906
            +        P+P I W +    +   E      D  +  L +T +  +E D G Y+C
Sbjct: 4510 QFSCSTLTTPLPQIRWSKEGRELIDMEKYCIRNDARSGILSLTVIGATEADIGQYEC 4566



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 48/218 (22%), Positives = 92/218 (42%), Gaps = 15/218 (6%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540
            S TV++ L+++  E      L C     P   V W ++   L+ A   +E +        
Sbjct: 2946 SVTVKENLQSVKAEEGAAASLCCELSK-PGASVQWKKNEVALR-AGGRFEMKQDGCLIQL 3003

Query: 1541 XXXXXXXYKCIAFNDH-GEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEG 1598
                       +++ H G+ +TS  + +++ P+  T S + ++ +   G    +   +  
Sbjct: 3004 QVKDLKLEDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQRVEVEE--GSSASLRCQLSK 3061

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             P   V W KN   L   ++Y +        +RIK++    S  YT  A N   + +VEV
Sbjct: 3062 -PGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAETSGAVEV 3120

Query: 1659 ----TLKVYDKPS---KPEGPV-IMREISRESVTIEWK 1688
                TL + +  S   +  G V +  ++S+  V+++WK
Sbjct: 3121 KALPTLFITELQSVEAEEGGSVSLCCQLSKPGVSVQWK 3158



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            +AP F+ +L+     +G      C++   P  +  W +    ++ +  ++M   +  +  
Sbjct: 3168 LAPFFITELQSVEAEEGGAASLCCELSR-PAVKAQWKKNRIPLRANSRYEMK-QEGCLLQ 3225

Query: 568  LVIREVFPEDAGTFTCVAKNA 588
            L I+E+ PED G+++C A +A
Sbjct: 3226 LHIQELRPEDGGSYSCQAGSA 3246


>UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 545

 Score =  224 bits (548), Expect = 2e-56
 Identities = 159/554 (28%), Positives = 260/554 (46%), Gaps = 46/554 (8%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-----GDTHS 788
            PP+    L+ + V +G +V L   V G+P+P + W K+ KPV  LP +       G+ ++
Sbjct: 2    PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYT 61

Query: 789  ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            + ++K  +  D G Y  KA NS G   +S  + V     +  EPP F    ++IT+ E  
Sbjct: 62   L-VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPK--EPPKFERNLKDITIAEGC 118

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            + +   +VT +P P + WY N +++ P + +    D E+  L++ +   ++ SG Y CVA
Sbjct: 119  STRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDL-SGKYTCVA 177

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
             N     +    V +  E    V    +    EE + V     T    ST        + 
Sbjct: 178  ENEVENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVY----TMRDGSTS-------VL 226

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028
             +++ E+  E              D+G ++C      +S ML   E  P+F+++L+  EV
Sbjct: 227  VIENAELDDEAMYTCKAIN-----DLGEVEC------SSEMLPTDEAGPKFLQRLELKEV 275

Query: 1029 KEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
             E     LEVE++ +   VV W +DGE++KP  +    E  G +  L I NT++ DEGEY
Sbjct: 276  VEGSRTDLEVEVSGKPKPVVEWLKDGELVKPS-SLMTLETEGQVHTLTIMNTTLDDEGEY 334

Query: 1088 SCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWF 1140
            +CI +++    SCTAE+ V E   PP+ I +  + ++ +G  A FE  ++      V W 
Sbjct: 335  TCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWL 394

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196
            +DG  I+     Q+  +  +  L I D  L+D GEY+C    + G   C+  L V+E  +
Sbjct: 395  RDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVV 454

Query: 1197 --NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
               F  ++    L       +          +VTWYK +  IED  +F + SD  K +L+
Sbjct: 455  PPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLV 514

Query: 1255 IRKCTEDDQCEYTC 1268
            IR C   D   Y+C
Sbjct: 515  IRDCALSDTGSYSC 528



 Score =  142 bits (344), Expect = 9e-32
 Identities = 111/406 (27%), Positives = 180/406 (44%), Gaps = 47/406 (11%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD--DDNVATLVIREVFPEDAGT 580
           +   V+ E +V G P+P + WF +    KP ++ +  Y   D + + LVI     +D   
Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEG---KPIEENRRVYTMRDGSTSVLVIENAELDDEAM 238

Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640
           +TC A N  G    ++E++   P  + G                         P F ++ 
Sbjct: 239 YTCKAINDLGEVECSSEML---PTDEAG-------------------------PKFLQRL 270

Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
           + + V EGS   LE  +   P+P + WL  GE + P   +++  E  +H     L I N 
Sbjct: 271 ELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVH----TLTIMNT 326

Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
               EG YT +A N+ GE S    L ++ G + PPQ I    S+ + +G+     A+V G
Sbjct: 327 TLDDEGEYTCIAKNKVGEVSCTAELLVEEGMR-PPQFIVKPSSLQIMEGKMAKFEARVSG 385

Query: 761 NPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
            P P + W ++ +P+K       + + D   +TI+   K+ DEG YT  A +  G    S
Sbjct: 386 LPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTII-DAKLNDEGEYTCVATSKAGKDSCS 444

Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
             + V+E       PP F+ +   I + E    +   R+T  P P +TWY++   I    
Sbjct: 445 VELLVDEA----VVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGG 500

Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
                 D +   LVI +  +  D+G Y C A+N AG++S    +TI
Sbjct: 501 RFEIYSDDDKHSLVIRDC-ALSDTGSYSCKATNEAGQASCYGELTI 545



 Score =  133 bits (322), Expect = 4e-29
 Identities = 102/368 (27%), Positives = 166/368 (45%), Gaps = 26/368 (7%)

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            E   ++L   VT  P P + W+   + I  +  +    DG    LVI N + + D   Y 
Sbjct: 182  ENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRDGSTSVLVIENAELD-DEAMYT 240

Query: 906  CVASNSAGKSSHGARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYH 962
            C A N  G+    + +   D     F++ L+   E  EG    LE + S       +W  
Sbjct: 241  CKAINDLGEVECSSEMLPTDEAGPKFLQRLELK-EVVEGSRTDLEVEVSGKPKPVVEWLK 299

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI-- 1016
            + + +       +  EG+            D G   CI K++      +  L+V+E +  
Sbjct: 300  DGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRP 359

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKP-KKNKYDFEKRGHIRKL 1074
            P+FI K    ++ E  +A  E  ++     +V W RDG  IKP ++ + +FEK   +  L
Sbjct: 360  PQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSV--L 417

Query: 1075 YIRNTSVHDEGEYSCILRD----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEI 1128
             I +  ++DEGEY+C+       +SC+ E+ V E  +PPE + ++ N ++ +G  A F++
Sbjct: 418  TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFDV 477

Query: 1129 ELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183
             +T   A  V W+KD   I+     ++  D  K  L I DC L D G YSC    E G +
Sbjct: 478  RITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 537

Query: 1184 KCTAILTV 1191
             C   LT+
Sbjct: 538  SCYGELTI 545



 Score =  131 bits (317), Expect = 2e-28
 Identities = 101/373 (27%), Positives = 170/373 (45%), Gaps = 27/373 (7%)

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
            + ++V L  +V G P+P + W    KP+   + + T  DG T S+ +++  ++ DE +YT
Sbjct: 182  ENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRDGST-SVLVIENAELDDEAMYT 240

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             KA N  G  E S+ +    PT+E    P F+ R +   V E     L   V+  P P +
Sbjct: 241  CKAINDLGEVECSSEML---PTDEAG--PKFLQRLELKEVVEGSRTDLEVEVSGKPKPVV 295

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W ++ E++ PS  +T   +G+   L I N   + D G+Y C+A N  G+ S  A + ++
Sbjct: 296  EWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLD-DEGEYTCIAKNKVGEVSCTAELLVE 354

Query: 925  VEKVTFVKHLQK--SYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGR 980
             E +   + + K  S +  EGK    E + S       +W  + + I      +I  E  
Sbjct: 355  -EGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKD 413

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI--PEFIRKLQDFEVKEKDVA 1034
                        D G   C+   +      S  L+V E +  PEF+RK+ + E+ E ++A
Sbjct: 414  RSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIA 473

Query: 1035 ILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
              +V I    A +V W +D E+      +++         L IR+ ++ D G YSC   +
Sbjct: 474  RFDVRITGTPAPEVTWYKD-EVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATN 532

Query: 1094 E----SCTAEVTV 1102
            E    SC  E+T+
Sbjct: 533  EAGQASCYGELTI 545



 Score =  128 bits (308), Expect = 2e-27
 Identities = 103/361 (28%), Positives = 160/361 (44%), Gaps = 22/361 (6%)

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           E   + LE  +   P+P + W  +G+ I  +EN  V    D     SVL I N +   E 
Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEGKPI--EENRRVYTMRDGS--TSVLVIENAELDDEA 237

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
            YT  A+N  GE      + + T E   P+ ++ L+   V +G    L  +V G P+P +
Sbjct: 238 MYTCKAINDLGEVECSSEM-LPTDE-AGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVV 295

Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            W K+    KP   +  +++G  H++TI+    + DEG YT  A+N  G  E S   T E
Sbjct: 296 EWLKDGELVKPSSLMTLETEGQVHTLTIMN-TTLDDEGEYTCIAKNKVG--EVSC--TAE 350

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
              EE   PP FI +   + + E    K  ARV+  P P + W R+   I P       F
Sbjct: 351 LLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEF 410

Query: 884 DGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTID--VEKVTFVKHLQKSYET 940
             E    V+T +D+++ D G+Y CVA++ AGK S    + +D  V    FV+ +  + E 
Sbjct: 411 --EKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKI-SNIEL 467

Query: 941 EEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
            EG+    + + + T + +  WY ++  I      EI  +              D G   
Sbjct: 468 TEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYS 527

Query: 999 C 999
           C
Sbjct: 528 C 528



 Score =  103 bits (248), Expect = 4e-20
 Identities = 106/478 (22%), Positives = 191/478 (39%), Gaps = 52/478 (10%)

Query: 932  KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXXXXX 987
            K   +  E  EG TV L    + +   +  W+ + K +SG+ HR  E+   G        
Sbjct: 6    KSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIK 65

Query: 988  XXXXXDVGVIKC--------IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039
                 D G   C        +        + V  +  P+F R L+D  + E      +V+
Sbjct: 66   EARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQ 125

Query: 1040 IN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
            +  S    V W  +G++++P+ +  D         L + +  +   G+Y+C+  +E    
Sbjct: 126  VTGSPEPKVFWYHNGKLVQPRDH-VDIVHDDEHSSLILMHCPLDLSGKYTCVAENE---- 180

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157
                          ++N  V        E+E+T +   +V WF +G  I+ +  +    D
Sbjct: 181  --------------VENDAVR------LEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRD 220

Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCTA-ILTVEEPSINFTLRLP-EFILVPAN 1211
            G    L I + +LDD   Y+C    ++G  +C++ +L  +E    F  RL  + ++  + 
Sbjct: 221  GSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVEGSR 280

Query: 1212 TDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
            TD  L VE+  +   V  W K   +++ +   TL ++ +  TL I   T DD+ EYTC+ 
Sbjct: 281  TD--LEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIA 338

Query: 1271 L----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
                 +   T +L VE    PP+ +      +I  G            P P  EW+ + +
Sbjct: 339  KNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGR 398

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
             IK  +  +   +   + LTI   +  D G Y     +  G     + + + +   PP
Sbjct: 399  PIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPP 456



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 121/574 (21%), Positives = 227/574 (39%), Gaps = 59/574 (10%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQ 1161
            +PPE  + L++ +VN+GN  T  I +T      V WFKDG  +    H +  +   G+  
Sbjct: 1    IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60

Query: 1162 KLKIYDCDLDDAGEYSCEVGNS------KCTA-ILTV--EEPSINFTLRLPEFILVPANT 1212
             L I +    D G+Y C+  NS       C   +L V  +EP   F   L +  +    +
Sbjct: 61   TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPP-KFERNLKDITIAEGCS 119

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              +           V WY    +++  +   ++ D +  +LI+  C  D   +YTC    
Sbjct: 120  TRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTC---- 175

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
                             + + E E        V L V+    P+P   W    K I++ +
Sbjct: 176  -----------------VAENEVE-----NDAVRLEVEVTGEPKPVVLWFCEGKPIEENR 213

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
                  D  ++ L I+  E  D  +Y  +  N+ G  +    +   D+  P      LE+
Sbjct: 214  RVYTMRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQR-LEL 272

Query: 1393 DSSSINICWD-EPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449
                     D E E +G    ++ ++ + + +  +  ++++   +  T +I N   +   
Sbjct: 273  KEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEG 332

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             +   A N+V   + S T E   +++E       + KP  ++     +  +      G+P
Sbjct: 333  EYTCIAKNKV--GEVSCTAEL--LVEEGMRPPQFIVKP-SSLQIMEGKMAKFEARVSGLP 387

Query: 1510 QPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P+V W RDG+ +K  +       ++R               Y C+A +  G+   SC V
Sbjct: 388  GPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK--DSCSV 445

Query: 1566 GIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
             +     + +  E +++   +    G+       I G P PEV WYK+   +E+   + I
Sbjct: 446  ELLVDEAV-VPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEI 504

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             + +    + I++   S +  Y+ +A+N AG +S
Sbjct: 505  YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQAS 538



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 104/473 (21%), Positives = 189/473 (39%), Gaps = 51/473 (10%)

Query: 1226 DVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKV 1281
            +V W+K    +      +F +    +  TL+I++    D  +Y C   ++    T+   V
Sbjct: 33   EVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNV 92

Query: 1282 EVVEF----PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            +V+      PPK     ++  I  G      V     P+P   W  N K+++   H    
Sbjct: 93   DVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIV 152

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
             D + +SL +       +G Y    EN   +  V + V +  +P    KP +L       
Sbjct: 153  HDDEHSSLILMHCPLDLSGKYTCVAENEVENDAVRLEVEVTGEP----KPVVLWF----- 203

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
              C  +P           + E + + T     +++ + +   I+N + +    +   A+N
Sbjct: 204  --CEGKP-----------IEENRRVYT-----MRDGSTSVLVIENAELDDEAMYTCKAIN 245

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
              D+ +   ++E     +        +E  LK +      D+E+     G P+P V W +
Sbjct: 246  --DLGEVECSSEMLPTDEAGPKFLQRLE--LKEVVEGSRTDLEVEV--SGKPKPVVEWLK 299

Query: 1518 DGKKLKTAKA-TYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQ--KP 1571
            DG+ +K +   T E                    Y CIA N  GEV  +  + +++  +P
Sbjct: 300  DGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRP 359

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
               I      Q  + G      A + G+P PEV W ++G  ++  + + I  ++  SV+ 
Sbjct: 360  PQFIVKPSSLQIME-GKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLT 418

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            I + K +   +YT  A++ AG  S  V L V D+   P  P  +R+IS   +T
Sbjct: 419  IIDAKLNDEGEYTCVATSKAGKDSCSVELLV-DEAVVP--PEFVRKISNIELT 468



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 56/202 (27%), Positives = 82/202 (40%), Gaps = 12/202 (5%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENISVAIESDMH 689
           IPP F    +   V+EG+ + L   +   P+P++ W   G+ +  +P     V    +++
Sbjct: 1   IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQ 748
                L I   +    G Y   A N  GE +    + +     KEPP+    LK + + +
Sbjct: 61  ----TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAE 116

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLK 806
           G S     QV G+P P + W  N K V+          D HS  IL    +   G YT  
Sbjct: 117 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 176

Query: 807 AENSEGIAETSAVITVEEPTEE 828
           AEN     E  AV    E T E
Sbjct: 177 AENE---VENDAVRLEVEVTGE 195



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 4/101 (3%)

Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
           PT E     P F+++L  K   +GS    E +V G P+P + W +   ++KPS       
Sbjct: 258 PTDEA---GPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPS-SLMTLE 313

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +  V TL I     +D G +TC+AKN  G  S T EL+VE
Sbjct: 314 TEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVE 354



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 5/127 (3%)

Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           L DE  YT     K  +  D   V  +   +E  + P FV K+      +G   +F+ ++
Sbjct: 424 LNDEGEYTCVATSKAGK--DSCSV--ELLVDEAVVPPEFVRKISNIELTEGEIARFDVRI 479

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
            G P P++TW++    I+    F++Y DDD   +LVIR+    D G+++C A N AG AS
Sbjct: 480 TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDK-HSLVIRDCALSDTGSYSCKATNEAGQAS 538

Query: 594 STTELIV 600
              EL +
Sbjct: 539 CYGELTI 545



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 41/128 (32%), Positives = 62/128 (48%), Gaps = 5/128 (3%)

Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           L DE  YT   + K+ E    +    +   EE    P F+ K       +G   +FE +V
Sbjct: 328 LDDEGEYTCIAKNKVGE----VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARV 383

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
            G P P++ W R    IKP + FQ+ ++ D  + L I +    D G +TCVA + AG  S
Sbjct: 384 SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDR-SVLTIIDAKLNDEGEYTCVATSKAGKDS 442

Query: 594 STTELIVE 601
            + EL+V+
Sbjct: 443 CSVELLVD 450



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK--PSQDFQMYYDDDNVAT 567
           P F   LR     +G+TV     V G P+P++ WF+    +   P + F++    + V T
Sbjct: 3   PEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGE-VYT 61

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           LVI+E    D G + C A N+AG  +S+  + V
Sbjct: 62  LVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 94



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 21/78 (26%), Positives = 44/78 (56%), Gaps = 1/78 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F   L+     +G + +F+ QV G P P++ W+    +++P     + +DD++ ++L+
Sbjct: 103 PKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEH-SSLI 161

Query: 570 IREVFPEDAGTFTCVAKN 587
           +     + +G +TCVA+N
Sbjct: 162 LMHCPLDLSGKYTCVAEN 179



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 1596 IEGIPPPEVIWYKNGNKLEN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG- 1652
            + G P PEV W+K+G  +     + + +    +   + IKE + S + KY  +A N+AG 
Sbjct: 26   VTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGE 85

Query: 1653 -TSSVEVTLKVYDKPSKP 1669
             TSS  V + ++  P +P
Sbjct: 86   VTSSCNVDV-LHVAPKEP 102


>UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whole
            genome shotgun sequence; n=2; Clupeocephala|Rep:
            Chromosome undetermined SCAF14761, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 2528

 Score =  222 bits (543), Expect = 7e-56
 Identities = 253/1073 (23%), Positives = 428/1073 (39%), Gaps = 91/1073 (8%)

Query: 632  IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            +PP  + + + +  V EG  + L C + A P P+I W   G+ +     I +     M  
Sbjct: 250  VPPRITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHILPGGQM-- 307

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L++   +    G Y   A N  G+    I+L +       P++      +  + G 
Sbjct: 308  ----LQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPSLKPRLDAASDLVTPQVGS 363

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            SVILS +  G P P +TW KN   + A     + D + + I+  + V D+G YT K  N 
Sbjct: 364  SVILSCEAHGVPEPEVTWYKNGLQL-APRNGFEMDRYQLEIVGVQ-VADDGTYTCKVSNV 421

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G  + +  +TV  P      P L  + ++ +       + L  + +  PVPSITW ++ 
Sbjct: 422  AGQVDRTFRLTVHVP------PVLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDG 475

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              I  S     +  G  +EL    +      G Y CVA NS G++     +T+ V     
Sbjct: 476  TPIESSLQWQWSIRGNRLELGPLTL---AHGGVYTCVAENSEGQTQKDYALTVQVSPTIL 532

Query: 931  VKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                        G+ + LECQ +   T    W  +   + G D+R I+            
Sbjct: 533  DSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEGSALTLLR 592

Query: 989  XXXXDVGVIKCIV-----KDQETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEI-N 1041
                D G   C+      +  +  T+ V V  +I       ++  V +  V  LE ++  
Sbjct: 593  LSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAG 652

Query: 1042 SETADVVWERDGE--IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            S    + W ++G   ++ P+      +       L I    + D G Y+C+ R ++  AE
Sbjct: 653  SPPPQISWLKNGHPLLLSPRTRLLSADS-----VLRISPVQLSDSGVYTCVARSQAGLAE 707

Query: 1100 VTV---VELPPEI--ITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHI 1152
            ++    V++PP +  +  ++   + +G+  T   E  +G     + WFKDG  +  S H 
Sbjct: 708  LSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCE-ARGVPPPTLTWFKDGQPL--SLHR 764

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             L +DG++ +L++ D    DAG YSC    + G+S  T  LTV EP    +   PE + +
Sbjct: 765  NLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTSSTSPEELTI 824

Query: 1209 PANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
              N+   L      +P  TL  TW K    +E ++    I       + I K   +D   
Sbjct: 825  AVNSPLELECSATGVPPPTL--TWLKDGHPLELSD----IVQEDGHLIRISKVQVEDAGL 878

Query: 1266 YTCVLLD-AKSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
            YTC+    A    K     V+ PP +   D  +   +     +TL     + P P  EW 
Sbjct: 879  YTCLASSLAGEDGKNHWIRVQVPPTLFGSDEVKTLTVPVNGHLTLECLADSDPAPEIEWY 938

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             +   ++     +     +   L I++V   D+G+Y   + N  G + +   V IL    
Sbjct: 939  KDEVKVQLGGRVQQLAGGQY--LEIQEVRPEDSGLYSCVVTNMAGSSSLFFTVEIL---L 993

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            PP      +I  SS  +      + G   ++   VE     T  W        TQ     
Sbjct: 994  PP------KIRESSSEVT----THVGQDALLLCEVEEDAQATVTWRK-DGFPITQDHKYT 1042

Query: 1443 LKTNSSYRFRAYAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            L +  S R     +++      S +++    ++ I      +P +     N+T       
Sbjct: 1043 LLSEGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISPGPFNVTVTAGMRA 1102

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXXXYKCIAFND 1555
             L+C   G+P PKV+W R+GK L  ++ +   R                   ++C A ND
Sbjct: 1103 VLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFECTAVND 1162

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVG-DEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
             GE      V +Q  P I    +D+     V      +   ++G P P V+W K+G KL 
Sbjct: 1163 AGEERRVVEVILQVPPTI---EDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLS 1219

Query: 1615 N-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +    Y +     T ++ I  +  SH+ +YT  A N+AG +   ++L V + P
Sbjct: 1220 SRGGTYRVL---PTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESP 1269



 Score =  202 bits (492), Expect = 1e-49
 Identities = 237/1068 (22%), Positives = 427/1068 (39%), Gaps = 73/1068 (6%)

Query: 632  IPPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            + PT   S+ P       G ++ LEC+    P P ++WL  G  +   +N  +    +  
Sbjct: 527  VSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEG- 585

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               S L +  +     GTYT +AV+  G  +    L +        +   P + + V Q 
Sbjct: 586  ---SALTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVP-REVPVTQD 641

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
              V L  QV G+P P I+W KN  P+   P        S+  + P ++ D GVYT  A +
Sbjct: 642  SVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLSADSVLRISPVQLSDSGVYTCVARS 701

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G+AE S  + V+ P   +   P+     + +T+ +   + L       P P++TW+++
Sbjct: 702  QAGLAELSYDVQVQVPPGVDHVEPV-----EPVTIVQGSLVTLSCEARGVPPPTLTWFKD 756

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKV 928
             + +S    +    DG+   L + +V +  D+G Y CVASN AG S+    +T+ +  K+
Sbjct: 757  GQPLSLHRNLL--LDGQETRLQLPDVATS-DAGLYSCVASNQAGSSTKTFNLTVLEPPKM 813

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            T     ++         + LEC  +     +  W    K+   ++  +I+QE        
Sbjct: 814  TSSTSPEE-LTIAVNSPLELECSATGVPPPTLTWL---KDGHPLELSDIVQED-GHLIRI 868

Query: 987  XXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVE 1039
                  D G+  C+      E      ++  +P  +      EVK   V +     LE  
Sbjct: 869  SKVQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTL--FGSDEVKTLTVPVNGHLTLECL 926

Query: 1040 INSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
             +S+ A ++ W +D   +K +      +  G  + L I+     D G YSC++ + + ++
Sbjct: 927  ADSDPAPEIEWYKDE--VKVQLGGRVQQLAGG-QYLEIQEVRPEDSGLYSCVVTNMAGSS 983

Query: 1099 EV--TV-VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQL 1154
             +  TV + LPP+I         + G  A    E+ +   A V W KDG  I   +   L
Sbjct: 984  SLFFTVEILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTL 1043

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP 1209
              +G    L+++D  L DAG Y C V N      +   +     P+I+     P  + V 
Sbjct: 1044 LSEGS---LRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISPG---PFNVTVT 1097

Query: 1210 ANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
            A   A L+ E        V+W +    ++ ++       +   +L++   +++D+  + C
Sbjct: 1098 AGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFEC 1157

Query: 1269 VLLDAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
              ++     +  VEV+ + PP I D        + S V L    Q  PQP   W  +   
Sbjct: 1158 TAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAK 1217

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPG 1385
            +     T   + +    L I  V  + AG Y     N+ G A   +++T+ + P   P  
Sbjct: 1218 LSSRGGTYRVLPT--GLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESPEIGPMA 1275

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
            +   + +   ++  C  E +     +I +   E   I T   +SV  ++        +  
Sbjct: 1276 EEVQVVLHHGTVLPC--EAQGFPRPSITWQR-EGVSIATGHRLSV--LSNGALKFSRVTL 1330

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
              +  ++  A NE  ++    T    +V        P +  P    T+   + + L C+ 
Sbjct: 1331 GDAGMYQCLAKNEAGVA-VGRTRLVLQV-------PPVLSVPRMEYTSVLGQPVSLECVA 1382

Query: 1506 GGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             G P P+V W ++ +  ++ A                      Y C A N  G       
Sbjct: 1383 DGQPPPEVAWLKERRPVIEGAHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMR 1442

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            + IQ  P+I+ +  D+      G + L+    +G P P + W KNG  + N        +
Sbjct: 1443 LAIQVPPLISPAQTDLSVVQ--GFQALLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLR 1500

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                +I   E+  + +  +T  A+NTAG++  +  L +  +P+  E P
Sbjct: 1501 SGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELP 1548



 Score =  194 bits (472), Expect = 3e-47
 Identities = 245/1098 (22%), Positives = 434/1098 (39%), Gaps = 99/1098 (9%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            GS ++L C    +PEP++ W   G ++ P        E D +     L+I  V+   +GT
Sbjct: 362  GSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGF----EMDRYQ----LEIVGVQVADDGT 413

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766
            YT    N  G+      L +      PP +   L +S+    G  V LS Q  G P P+I
Sbjct: 414  YTCKVSNVAGQVDRTFRLTVHV----PPVLEGSLWESLNYTLGSHVTLSCQASGFPVPSI 469

Query: 767  TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EP 825
            TW K+  P+++          +   L P  +   GVYT  AENSEG  +    +TV+  P
Sbjct: 470  TWLKDGTPIESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYALTVQVSP 529

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNF 883
            T  ++E P       E++      + L  + T NP P ++W ++  I+  S+   I    
Sbjct: 530  TILDSEHP------SEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATP 583

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEE 942
            +G  + L+  + D   DSG Y C+A + AG+ +    + + V   +     + +     +
Sbjct: 584  EGSALTLLRLSPD---DSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQ 640

Query: 943  GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
               V LECQ   S      W  N   +       ++                D GV  C+
Sbjct: 641  DSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLSAD--SVLRISPVQLSDSGVYTCV 698

Query: 1001 VKDQETSTMLV--VKETIP---EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE 1054
             + Q     L   V+  +P   + +  ++   + +  +  L  E        + W +DG+
Sbjct: 699  ARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQ 758

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEII 1110
             +   +N       G   +L + + +  D G YSC+  +++     T  +TV+E PP++ 
Sbjct: 759  PLSLHRNLL---LDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLE-PPKMT 814

Query: 1111 TRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
            +    +++     +  E+E +        + W KDG  ++ S+ +Q   DG    ++I  
Sbjct: 815  SSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPLELSDIVQE--DG--HLIRISK 870

Query: 1168 CDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI--- 1220
              ++DAG Y+C      G       + V+ P   F     + + VP N   +LT+E    
Sbjct: 871  VQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLFGSDEVKTLTVPVN--GHLTLECLAD 928

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
             D   ++ WYK +  ++   +   ++    + L I++   +D   Y+CV+ +   ++ L 
Sbjct: 929  SDPAPEIEWYKDEVKVQLGGRVQQLAG--GQYLEIQEVRPEDSGLYSCVVTNMAGSSSLF 986

Query: 1281 VEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI 1338
              V +  PPKI +   E     G D  LL + +   Q    W  +   I +  K+T  S 
Sbjct: 987  FTVEILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTLLS- 1045

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNI-LEIDSS 1395
                 SL +  V+ +DAG Y   + N  G  H  + + V +    SP G  N+ +     
Sbjct: 1046 ---EGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISP-GPFNVTVTAGMR 1101

Query: 1396 SINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR-FRA 1453
            ++  C    E TG     + +    + +D ++      +  + + +    ++     F  
Sbjct: 1102 AVLSC----ETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFEC 1157

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
             AVN     DA E     +VI +     PT+E  +  +T      + L C   G PQP V
Sbjct: 1158 TAVN-----DAGEERRVVEVILQVP---PTIEDDVTAVTAVKMSPVALPCHVQGRPQPTV 1209

Query: 1514 TWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
             W + G KL +   TY                    Y C A N  G       + +Q+ P
Sbjct: 1210 VWTKSGAKLSSRGGTYRVLPTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESP 1269

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             I    E+++     G   ++    +G P P + W + G  +      ++ +      ++
Sbjct: 1270 EIGPMAEEVQVVLHHGT--VLPCEAQGFPRPSITWQREGVSIATGHRLSVLS---NGALK 1324

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTL-----KVYDKPSKPEGPVIMREISRESVTIE 1686
               +    +  Y   A N AG +     L      V   P      V+ + +S E V  +
Sbjct: 1325 FSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRMEYTSVLGQPVSLECVA-D 1383

Query: 1687 WKPPLDDGGLELTKYAIE 1704
             +PP +   L+  +  IE
Sbjct: 1384 GQPPPEVAWLKERRPVIE 1401



 Score =  186 bits (452), Expect = 8e-45
 Identities = 254/1192 (21%), Positives = 459/1192 (38%), Gaps = 120/1192 (10%)

Query: 508  MAPIFVEKLRPKHT--PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            ++P  ++   P     P G  +  ECQ  G P P ++W +   I++ S +  +    +  
Sbjct: 527  VSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEGS 586

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
            A  ++R + P+D+GT+TC+A + AG  +    L V  P S  G E TV            
Sbjct: 587  ALTLLR-LSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAG-ETTV------------ 632

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
                          P+   V + S + LEC++   P P I+WL  G  ++      + + 
Sbjct: 633  --------------PREVPVTQDSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRL-LS 677

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKS 743
            +D     SVL+I+ V+    G YT VA ++ G A L   ++++     PP V  +EP++ 
Sbjct: 678  AD-----SVLRISPVQLSDSGVYTCVARSQAGLAELSYDVQVQV----PPGVDHVEPVEP 728

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
            + + QG  V LS +  G P PT+TW K+ +P+            +   L      D G+Y
Sbjct: 729  VTIVQGSLVTLSCEARGVPPPTLTWFKDGQPLSLHRNLLLDGQETRLQLPDVATSDAGLY 788

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            +  A N  G +  +  +TV EP +  +         +E+T+     ++L    T  P P+
Sbjct: 789  SCVASNQAGSSTKTFNLTVLEPPKMTSS-----TSPEELTIAVNSPLELECSATGVPPPT 843

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +TW ++   +  S+ + +  DG  I +    V+   D+G Y C+AS+ AG+      + +
Sbjct: 844  LTWLKDGHPLELSDIVQE--DGHLIRISKVQVE---DAGLYTCLASSLAGEDGKNHWIRV 898

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981
             V    F     K+        + LEC   +      +WY  K E+       + Q    
Sbjct: 899  QVPPTLFGSDEVKTLTVPVNGHLTLECLADSDPAPEIEWY--KDEVKVQLGGRVQQLAGG 956

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTML--VVKETIPEFIRKLQD---FEVKEKDVAIL 1036
                       D G+  C+V +   S+ L   V+  +P  IR+        V +  + + 
Sbjct: 957  QYLEIQEVRPEDSGLYSCVVTNMAGSSSLFFTVEILLPPKIRESSSEVTTHVGQDALLLC 1016

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
            EVE +++ A V W +DG  I  + +KY     G +R   + +  + D G Y C + +++ 
Sbjct: 1017 EVEEDAQ-ATVTWRKDGFPI-TQDHKYTLLSEGSLR---VHDVQLSDAGRYYCSVSNQAG 1071

Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEI---QFS 1149
            +    +   V + P I     N  V  G +A    E T      V W ++G  +   Q S
Sbjct: 1072 SDHRGIYLRVFVAPAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLS 1131

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPE 1204
               +L   G    L   D   +D G + C   N      +   ++    P+I   +    
Sbjct: 1132 GAFRLLSSGSLVLLSPSD---EDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVT 1188

Query: 1205 FI-LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             + + P     ++    P  T  V W K  + +  + +      +    L I        
Sbjct: 1189 AVKMSPVALPCHVQGR-PQPT--VVWTKSGAKL--SSRGGTYRVLPTGLLEITAVLPSHA 1243

Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
              YTC   ++       + + V+  P+I     E ++       L  + Q FP+P+  W 
Sbjct: 1244 GRYTCSARNSAGLAHKHISLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITW- 1302

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
               + +      + S+ S  A L   +V   DAG+Y+   +N  G   V +  T L    
Sbjct: 1303 -QREGVSIATGHRLSVLSNGA-LKFSRVTLGDAGMYQCLAKNEAG---VAVGRTRLVLQV 1357

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            PP    +L +          +P +      +  V + Q      W+  +        I+ 
Sbjct: 1358 PP----VLSVPRMEYTSVLGQPVS------LECVADGQPPPEVAWLKERRPVIEGAHIR- 1406

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK--IQSPTVEKPLK-NITTEPNEDI 1499
            +  N +    +   ++  +   +      +   + +  IQ P +  P + +++       
Sbjct: 1407 IFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVPPLISPAQTDLSVVQGFQA 1466

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFND 1555
             L C   G P+P+++W ++G  +      Y                      + C+A N 
Sbjct: 1467 LLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLRSGELIIERAEVSWADAGVFTCVATNT 1526

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             G       + I  +P       D+      G    ++   +G PPP + W  N     N
Sbjct: 1527 AGSARQDSRLSINMRPAFKELPGDVTLNK--GQNLALSCHAQGTPPPVISWTVN-----N 1579

Query: 1616 DKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
              +   T  E   S + I+ +  SH+  Y   A N+ G+      ++V + P
Sbjct: 1580 SPQTGATLDESGRSSLIIENVTTSHAGTYVCIAENSVGSIRALSFVRVREPP 1631



 Score =  161 bits (392), Expect = 1e-37
 Identities = 188/843 (22%), Positives = 330/843 (39%), Gaps = 69/843 (8%)

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
            +L+I        G +TCV  N AG       + ++ P   H                   
Sbjct: 10   SLIIENTMLFHEGQYTCVVTNTAGEDKRDFRVTIQVPPVFHRVTNREAAWGLGHEGDDKD 69

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
            D++E +               G  + L C   AIP P ++W   G++++  + + V +  
Sbjct: 70   DMVERLDVVL-----------GHPVSLSCESNAIPPPKLSWHKDGQKLMSGDGV-VLLPG 117

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                   VL+I  V+K   G YT  AVN  GE  +   L I           E ++ M  
Sbjct: 118  -----AQVLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHILVPPVITGATEEFMEEMAA 172

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
                +V+L   V G P P ++W K+ +PV+  P        +   L   +V D   Y   
Sbjct: 173  VVNSTVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQLHLLRVQVSDMAGYLCV 232

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            AEN  G  E    +TV+ P      P +     +E++V E   + L+  V   P P ITW
Sbjct: 233  AENKVGTVEKLFSLTVQVP------PRITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITW 286

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             R+ ++++    I     G+ ++L    ++   D+G Y C A+NSAG+      +++ V 
Sbjct: 287  TRDGQVLAFGSGIHILPGGQMLQLPRARLE---DAGQYVCTATNSAGQDQKSILLSVYV- 342

Query: 927  KVTFVKHLQKSYE---TEEGKTVILECQTSHTV---STKWYHNKKEISGMDHREIIQEGR 980
            + +    L  + +    + G +VIL C+ +H V      WY N  +++  +  E+ +   
Sbjct: 343  RPSLKPRLDAASDLVTPQVGSSVILSCE-AHGVPEPEVTWYKNGLQLAPRNGFEMDR--- 398

Query: 981  XXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAIL 1036
                        D G   C V +   Q   T  +     P     L +           L
Sbjct: 399  -YQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLNYTLGSHVTL 457

Query: 1037 EVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
              + +      + W +DG  I+    ++ +  RG+  +L +   ++   G Y+C+  +  
Sbjct: 458  SCQASGFPVPSITWLKDGTPIE-SSLQWQWSIRGN--RLELGPLTLAHGGVYTCVAENSE 514

Query: 1096 CTAE---VTVVELPPEIITRLQNQKVN--KGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149
               +      V++ P I+      +V+   G + + E + T      + W KDG  ++ S
Sbjct: 515  GQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGS 574

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG-NSKCTAILTVEEPSINFTLRLPE 1204
            ++  +    +   L +     DD+G Y+C      G  +K   +  +  PSI     +P 
Sbjct: 575  DNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPR 634

Query: 1205 FILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
               VP   D+ +T+E          ++W K    +  + +  L+S      L I      
Sbjct: 635  --EVPVTQDSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLS--ADSVLRISPVQLS 690

Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
            D   YTCV        +L  +V V+ PP +  V+      I +GS VTL  + +  P P 
Sbjct: 691  DSGVYTCVARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPT 750

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
              W  + + +    H    +D +   L +  V  +DAG+Y     N  G +    N+T+L
Sbjct: 751  LTWFKDGQPLS--LHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVL 808

Query: 1379 DKP 1381
            + P
Sbjct: 809  EPP 811



 Score =  126 bits (303), Expect = 9e-27
 Identities = 217/1080 (20%), Positives = 386/1080 (35%), Gaps = 107/1080 (9%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            VE + P     GS V   C+  G P P +TWF+    +   ++  +   D     L + +
Sbjct: 723  VEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQPLSLHRNLLL---DGQETRLQLPD 779

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
            V   DAG ++CVA N    A S+T+             +TV               LE  
Sbjct: 780  VATSDAGLYSCVASNQ---AGSSTKTF----------NLTV---------------LEPP 811

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
              T S  P+   +   S + LEC    +P P + WL  G  +     +S  ++ D H+  
Sbjct: 812  KMTSSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPL----ELSDIVQEDGHL-- 865

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGE 750
              ++I+ V+    G YT +A +  GE      ++++     PP +   + +K++ V    
Sbjct: 866  --IRISKVQVEDAGLYTCLASSLAGEDGKNHWIRVQV----PPTLFGSDEVKTLTVPVNG 919

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             + L      +P P I W K+   V+    +   + G    I  ++P   +D G+Y+   
Sbjct: 920  HLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVRP---EDSGLYSCVV 976

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G   +S   TV     E   PP       E+T        L+  V  +   ++TW 
Sbjct: 977  TNMAG--SSSLFFTV-----EILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWR 1029

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++   I+     T   +G    L + +V    D+G Y C  SN AG    G  + + V  
Sbjct: 1030 KDGFPITQDHKYTLLSEG---SLRVHDVQLS-DAGRYYCSVSNQAGSDHRGIYLRVFVAP 1085

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXX 985
               +     +     G   +L C+T+     K  W  N K +         +        
Sbjct: 1086 A--ISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLV 1143

Query: 986  XXXXXXXDVGVIKC-IVKD--QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                   D G  +C  V D  +E   + V+ +  P     +      +     L   +  
Sbjct: 1144 LLSPSDEDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQG 1203

Query: 1043 E-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
                 VVW + G  +  +   Y     G    L I        G Y+C  R+ +  A   
Sbjct: 1204 RPQPTVVWTKSGAKLSSRGGTYRVLPTG---LLEITAVLPSHAGRYTCSARNSAGLAHKH 1260

Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTID 1157
            +   V+  PEI    +  +V   +      E        + W ++G  I   + + +  +
Sbjct: 1261 ISLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSIATGHRLSVLSN 1320

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTD 1213
            G    LK     L DAG Y C   N    A+    L ++ P +    R+ E+  V     
Sbjct: 1321 G---ALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRM-EYTSVLGQPV 1376

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL--L 1271
            +   V       +V W K++  + +     + ++    TL I      D   YTC    L
Sbjct: 1377 SLECVADGQPPPEVAWLKERRPVIEGAHIRIFAN---GTLAIASTQRSDAGLYTCTAKNL 1433

Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
              +++  +++  ++ PP I   + +  + +G    L    Q  P+P   W  N   +   
Sbjct: 1434 AGRASHDMRL-AIQVPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPNL 1492

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
                  + S    +   +V   DAG++     N  G A  +  ++I  +P+    P  + 
Sbjct: 1493 PGKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELPGDVT 1552

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
            ++           + T    I + V    +   T    +    ++   I+N+ T+ +  +
Sbjct: 1553 LNKGQNLALSCHAQGTPPPVISWTVNNSPQTGAT----LDESGRSSLIIENVTTSHAGTY 1608

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI--TTEPNEDIELTCIFGGVP 1509
               A N V            + +   +++ P V K    +  T        L C   G P
Sbjct: 1609 VCIAENSVG---------SIRALSFVRVREPPVLKGEARMSQTVVQGSSAILDCPIHGDP 1659

Query: 1510 QPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             P + W RDG   L++ +                     Y+C+A ++ G  E +  + +Q
Sbjct: 1660 SPVLQWLRDGHPLLRSHRIQALLNGSLVIYSINAADEGEYQCLAESEAGTAERTITLKVQ 1719



 Score =  103 bits (246), Expect = 7e-20
 Identities = 127/559 (22%), Positives = 218/559 (38%), Gaps = 40/559 (7%)

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194
            W KDG ++   + + L + G  Q L+I     +DAG Y+C    E G       L +  P
Sbjct: 99   WHKDGQKLMSGDGVVL-LPGA-QVLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHILVP 156

Query: 1195 SI--NFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
             +    T    E +    N+   L  ++  + T  V+W K    ++   +  +  D  + 
Sbjct: 157  PVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQL 216

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLV 1309
             L+  +    D   Y CV  +   T  KL    V+ PP+I    E E  +  G  V+LL 
Sbjct: 217  HLL--RVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPPRITGRMEEEVSVTEGRMVSLLC 274

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCK--HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            D QA+P P   W  + +++      H  P        L + +    DAG Y     N+ G
Sbjct: 275  DVQAYPPPEITWTRDGQVLAFGSGIHILPG----GQMLQLPRARLEDAGQYVCTATNSAG 330

Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
                 + +++  +PS   KP +   D++S  +    P+  G+S I+    E   +   E 
Sbjct: 331  QDQKSILLSVYVRPSL--KPRL---DAASDLVT---PQ-VGSSVILS--CEAHGVPEPEV 379

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-----ASETTEYYKVIKETKIQSP 1482
               KN    Q + +N      Y+     V   D        ++   +  +  + T    P
Sbjct: 380  TWYKN--GLQLAPRNGFEMDRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPP 437

Query: 1483 TVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXX- 1539
             +E  L +++       + L+C   G P P +TW +DG  ++++ +  +  R        
Sbjct: 438  VLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNRLELGP 497

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y C+A N  G+ +    + +Q  P I  S    +    +G+E  +     G 
Sbjct: 498  LTLAHGGVYTCVAENSEGQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGN 557

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P + W K+G  +E     +I    + S + +  L    S  YT  A + AG  +   T
Sbjct: 558  PTPHLSWLKDGVIVEGSDNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAGRQTKIYT 617

Query: 1660 LKVYDKPSKPEGPVIMREI 1678
            L V   PS      + RE+
Sbjct: 618  LFVLVPPSIAGETTVPREV 636



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 75/294 (25%), Positives = 115/294 (39%), Gaps = 20/294 (6%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP  S       V +G   LL C     PEP I+W   G   VP+      +     + 
Sbjct: 1447 VPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTP-VPNLPGKYTVLRSGEL- 1504

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              +++   V     G +T VA N  G A     L I       P   E    + + +G++
Sbjct: 1505 --IIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMR----PAFKELPGDVTLNKGQN 1558

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + LS    G P P I+W  NN P         G   S  I++       G Y   AENS 
Sbjct: 1559 LALSCHAQGTPPPVISWTVNNSPQTGATLDESG--RSSLIIENVTTSHAGTYVCIAENSV 1616

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G     + + V EP     E      R  +  V+    I L   +  +P P + W R+  
Sbjct: 1617 GSIRALSFVRVREPPVLKGEA-----RMSQTVVQGSSAI-LDCPIHGDPSPVLQWLRDGH 1670

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
             +  S  I    +G    LVI ++++  D G+Y+C+A + AG +     + + V
Sbjct: 1671 PLLRSHRIQALLNGS---LVIYSINAA-DEGEYQCLAESEAGTAERTITLKVQV 1720



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 83/448 (18%), Positives = 168/448 (37%), Gaps = 21/448 (4%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285
            ++W+K    +   +   L+   +   L I +  ++D   YTC  ++      +  E+ + 
Sbjct: 97   LSWHKDGQKLMSGDGVVLLPGAQ--VLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHIL 154

Query: 1286 FPPKIVDYEREYRIKRG----SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             PP I     E+  +      S V L  D    P P   W+ + + ++     +  I   
Sbjct: 155  VPPVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQT--DPQHQISKD 212

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG--KPNILEIDSSSINI 1399
               L + +V+ +D   Y    EN  G  +   ++T+   P   G  +  +   +   +++
Sbjct: 213  GTQLHLLRVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPPRITGRMEEEVSVTEGRMVSL 272

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
              D          I +  + Q +     I +    +    +   +   + ++   A N  
Sbjct: 273  LCDVQAYPPPE--ITWTRDGQVLAFGSGIHILPGGQ-MLQLPRARLEDAGQYVCTATNSA 329

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
                 S     Y V    K   P ++     +T +    + L+C   GVP+P+VTWY++G
Sbjct: 330  GQDQKSILLSVY-VRPSLK---PRLDAASDLVTPQVGSSVILSCEAHGVPEPEVTWYKNG 385

Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
             +L        +R               Y C   N  G+V+ +  + +   PV+  S  +
Sbjct: 386  LQLAPRNGFEMDRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWE 445

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                + +G    ++    G P P + W K+G  +E+  ++  + +     + +  L  +H
Sbjct: 446  -SLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNR--LELGPLTLAH 502

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
               YT  A N+ G +  +  L V   P+
Sbjct: 503  GGVYTCVAENSEGQTQKDYALTVQVSPT 530



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%)

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            + L+C    +P PK++W++DG+KL +                         Y C A N+ 
Sbjct: 83   VSLSCESNAIPPPKLSWHKDGQKLMSGDGVVLLPGAQVLQIARVQKEDAGRYTCQAVNEA 142

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            GE      + I   PVIT + E+  ++    V    ++   + G P P V W K+G  ++
Sbjct: 143  GEDHMHFELHILVPPVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQ 202

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             D ++ I +K+ T  + +  ++ S  + Y   A N  GT     +L V   P
Sbjct: 203  TDPQHQI-SKDGTQ-LHLLRVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPP 252



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 4/173 (2%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
            ++T    +++ L+C   G P P ++W  +      A      R               Y 
Sbjct: 1550 DVTLNKGQNLALSCHAQGTPPPVISWTVNNSPQTGATLDESGRSSLIIENVTTSHAGTYV 1609

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            CIA N  G +     V +++ PV+      + Q    G   ++   I G P P + W ++
Sbjct: 1610 CIAENSVGSIRALSFVRVREPPVLK-GEARMSQTVVQGSSAILDCPIHGDPSPVLQWLRD 1668

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            G+ L   + + I      S++ I  +  +   +Y   A + AGT+   +TLKV
Sbjct: 1669 GHPLL--RSHRIQALLNGSLV-IYSINAADEGEYQCLAESEAGTAERTITLKV 1718



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
           TP  GS+V   C+  G P P++TW++    + P   F+M     +   L I  V   D G
Sbjct: 358 TPQVGSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGFEM-----DRYQLEIVGVQVADDG 412

Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
           T+TC   N AG    T  L V  P    GS
Sbjct: 413 TYTCKVSNVAGQVDRTFRLTVHVPPVLEGS 442



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V   CQ  G+P P ITW +    I+ S  +Q     +    L +  +     G +TC
Sbjct: 452 GSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNR---LELGPLTLAHGGVYTC 508

Query: 584 VAKNAAGFASSTTELIVE-APL---SDHGSEMT 612
           VA+N+ G       L V+ +P    S+H SE++
Sbjct: 509 VAENSEGQTQKDYALTVQVSPTILDSEHPSEVS 541



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            +M P F E         G  +   C  +G P P I+W      +  S       D+   +
Sbjct: 1539 NMRPAFKELPGDVTLNKGQNLALSCHAQGTPPPVISW-----TVNNSPQTGATLDESGRS 1593

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +L+I  V    AGT+ C+A+N+ G   + + + V  P
Sbjct: 1594 SLIIENVTTSHAGTYVCIAENSVGSIRALSFVRVREP 1630



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 3/79 (3%)

Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           STV   C V G P P ++W +    ++     Q+  D   +  L    V   D   + CV
Sbjct: 176 STVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQLHLL---RVQVSDMAGYLCV 232

Query: 585 AKNAAGFASSTTELIVEAP 603
           A+N  G       L V+ P
Sbjct: 233 AENKVGTVEKLFSLTVQVP 251



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G  V   C V+ YP P+ITW R   ++       +         L +     EDAG + 
Sbjct: 266 EGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHIL---PGGQMLQLPRARLEDAGQYV 322

Query: 583 CVAKNAAG 590
           C A N+AG
Sbjct: 323 CTATNSAG 330



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 5/93 (5%)

Query: 510  PIFVEKLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P+   + R   T   GS+   +C + G P P + W R    +  S   Q   +     +L
Sbjct: 1631 PVLKGEARMSQTVVQGSSAILDCPIHGDPSPVLQWLRDGHPLLRSHRIQALLN----GSL 1686

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            VI  +   D G + C+A++ AG A  T  L V+
Sbjct: 1687 VIYSINAADEGEYQCLAESEAGTAERTITLKVQ 1719


>UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB
            isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to
            CG33519-PB isoform 1 - Apis mellifera
          Length = 2794

 Score =  219 bits (534), Expect = 9e-55
 Identities = 234/945 (24%), Positives = 394/945 (41%), Gaps = 90/945 (9%)

Query: 488  LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
            L ++  K  + E+ ++EE +   I    L  K   +  T+ FE +    PR    WF+  
Sbjct: 374  LEKESSKADILERESTEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDG 433

Query: 548  AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
              ++  +  ++    +    + + ++  ED G +TC   N                    
Sbjct: 434  KPLRSGERVRIESSGERFR-MELSKIIIEDEGVYTCSFSNKL------------------ 474

Query: 608  GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667
            G +MT              D L    P F +  +   V  G   + +    A P PDI W
Sbjct: 475  GEDMT-----EGYLTVQTVDELRR--PKFIETLQDVDVANGKSGMFKAMFTADPVPDITW 527

Query: 668  LFKGEEI-VPDENISVAIE----SDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASL 721
             FKG+EI   D  + + ++    SD     +V L +    K   G YT+   N+ GEA  
Sbjct: 528  YFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAES 587

Query: 722  PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---L 778
               L +    +     I+ L  +    GES+   A + GNP+P ITW K+ K ++     
Sbjct: 588  NAFLNLLLCPE-----IQELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERY 642

Query: 779  PTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF-- 835
              + D   +  T ++K  ++ D+G Y + A+N  G A   A++T        +E P+F  
Sbjct: 643  DFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGEASAQAILT------PYSETPIFSE 696

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVIT 893
            I   + +  K++  ++   R +  P P++ W R NE I   +   I    DG N+E V +
Sbjct: 697  ILPKKPVECKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCS 756

Query: 894  -NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
                   D G   C ASN  G +     + + +   +FV  L KS E +EG  + L+ + 
Sbjct: 757  ITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLLPKSTEVDEGGCLELKAKI 816

Query: 953  --SHTVSTKWYHNKKEISGMDHR--EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ET 1006
              S      WY + ++I   +H   EI+ +G             D G  K ++ +   E 
Sbjct: 817  DGSPMPEISWYKDGEKIVPDEHTRIEILPDG-TTKLIIDCVQPLDCGAYKLVINNSTGEQ 875

Query: 1007 STMLVV----KETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN 1061
            S++  V    +   P F + L+D ++   +   LE ++ +    +V W ++G  ++  K 
Sbjct: 876  SSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKE 935

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELP--PEIITRLQN 1115
             Y   +   I  L I +    D G YS      L + + TA+V + E    PE +  LQ 
Sbjct: 936  MYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQP 995

Query: 1116 QKVNKGNKATFEIE-LTKGDALVRWFKDGSEI-QFSNHIQ-LTIDGKKQKLKIYDCDLDD 1172
              V +G  A  E++ L K    ++WFK+G EI      ++ +++    Q L I     +D
Sbjct: 996  LSVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPED 1055

Query: 1173 AGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFI------LVPANTDAYLTVEIP 1221
            AGEY    GN++ T+     I  V +   + + + P F+       V       L+V   
Sbjct: 1056 AGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFV 1115

Query: 1222 DETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL---LDAKST- 1276
               + DV W K  + ++ +++FT+  D KK  L I  C   D   Y C +   L   ST 
Sbjct: 1116 GNPIPDVNWSKDGAPLQPSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTR 1175

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTK 1335
            +   V  +  PP  +   ++ +     D   L      P+P+  W VN K I++     K
Sbjct: 1176 STANVRKIFQPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYK 1235

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
               D  +  L +K     D+G+YK R  N  G A+   N+TI+D+
Sbjct: 1236 IKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAANLTIVDE 1280



 Score =  203 bits (496), Expect = 4e-50
 Identities = 228/904 (25%), Positives = 363/904 (40%), Gaps = 93/904 (10%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  +  +  +   P+PDI W   G+ +   E      E D       L I  V+   +G 
Sbjct: 610  GESLAWQAIIKGNPKPDITWSKDGKVLEKGERYD--FEEDKRNNKFTLVIKEVEIDDKGA 667

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGNPRPT 765
            Y V A N  GEAS   +L   T   E P   E  P K +  +    V    +  G PRP 
Sbjct: 668  YQVTAKNYLGEASAQAIL---TPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPN 724

Query: 766  ITWCKNNKPVKA-----LPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            + W + N+ ++      +  + DG+   S+  +      D G  T +A N  G A+TS  
Sbjct: 725  LKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCD 784

Query: 820  ITVEEPTEENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            + V+  T      P F+N   + T V E G ++L A++  +P+P I+WY++ E I P E 
Sbjct: 785  LLVQLIT------PSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEH 838

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE--KVTFVKHLQK 936
                   +    +I +    +D G YK V +NS G+ S    V I  E  K +F K L+ 
Sbjct: 839  TRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLE- 897

Query: 937  SYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXD 993
              +   G+ + LE Q         +W+ N   +        I E               D
Sbjct: 898  DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPED 957

Query: 994  VGVIKCIVKD---QETSTMLV---VKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETAD 1046
             G     V +   + T T  V    KE  PEF+  LQ   V E   A +EV++    T  
Sbjct: 958  AGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPR 1017

Query: 1047 VVWERDGEIIKPK-KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVT 1101
            + W ++GE I P  K           + L I   +  D GEY  I  +     SC   ++
Sbjct: 1018 LQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTIS 1077

Query: 1102 VV--------ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151
            VV        E  P  +  +++  V +G      +    G+ +  V W KDG+ +Q S+ 
Sbjct: 1078 VVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFV-GNPIPDVNWSKDGAPLQPSDR 1136

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTA-ILTVEEPSINFTLRLPE 1204
              +T DGKK +L+I  C+  DAG Y C + N      ++ TA +  + +P  +F     +
Sbjct: 1137 FTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIFQPP-SFIHAFKD 1195

Query: 1205 FILVPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
               +P     +L         D+TWY  +K +++D +K+ +  D     L ++ CT DD 
Sbjct: 1196 LQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDS 1255

Query: 1264 CEYTC--VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA-------- 1313
              Y C  V    ++     + +V+   KI  +E    +KR  D  +     A        
Sbjct: 1256 GVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTG 1315

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH----A 1369
             P+P+ EW  N   + +    +   +     LTI  V+  DAG Y L++ N  G     A
Sbjct: 1316 IPEPDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTA 1375

Query: 1370 DVEMNV-------------TILDK------PSP-PGKPNILEIDSSSINICWDEPENTGN 1409
            D+                    DK      P P   +P I  +    + + W      G+
Sbjct: 1376 DLIYETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRHLTLSWKPSIPIGS 1435

Query: 1410 STIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
               + Y +E  E+   +W + +  I      I+NL+    Y+FR    N+  ISD S   
Sbjct: 1436 RIPVTYQIEMCELPDGDWFTARTGIRSCVCDIRNLEPFRDYKFRIRVENKYGISDPSPYA 1495

Query: 1469 EYYK 1472
            + Y+
Sbjct: 1496 QTYR 1499



 Score =  182 bits (442), Expect = 1e-43
 Identities = 224/956 (23%), Positives = 389/956 (40%), Gaps = 79/956 (8%)

Query: 630  EGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            E  PP   K   A + V E   I+ E    ++P  D  W   G+ +   E   V IES  
Sbjct: 391  ESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGER--VRIESSG 448

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKEPPQVIEPLKSMIVR 747
              +   ++++ +    EG YT    N+ GE      L ++T  E   P+ IE L+ + V 
Sbjct: 449  ERFR--MELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVA 506

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----------SDGDTHS-ITILKPKK 796
             G+S +  A    +P P ITW      + +  ++          SD  T + +T+  PK 
Sbjct: 507  NGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKC 566

Query: 797  VKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
             KD+ G YTLK +N  G AE++A + +    E        I    ++T     ++   A 
Sbjct: 567  SKDDTGEYTLKLKNKYGEAESNAFLNLLLCPE--------IQELNDVTTNVGESLAWQAI 618

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS-GDYKCVASNSAGK 914
            +  NP P ITW ++ +++   E      D  N +  +   + EID  G Y+  A N  G+
Sbjct: 619  IKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGE 678

Query: 915  SSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMD 971
            +S  A +T   E   F + L +K  E ++   V  +  C      + KW    +EI   D
Sbjct: 679  ASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDD 738

Query: 972  HREII--QEGRXXXXXXXXXXX--XDVGVIKC----IVKDQETSTMLVVKETIPEFIRKL 1023
              +I+  ++G               DVG I C    I    +TS  L+V+   P F+  L
Sbjct: 739  RYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLL 798

Query: 1024 -QDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
             +  EV E     L+ +I+ S   ++ W +DGE I P ++           KL I     
Sbjct: 799  PKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQP 858

Query: 1082 HDEGEYSCILRDES------CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GD 1134
             D G Y  ++ + +      C   +      P     L++ K+  G     E ++    +
Sbjct: 859  LDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEAQVVAFPN 918

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGNS--KCTAILTV 1191
              V+WFK+G  ++ +  +    +      L+I  C  +DAG YS  V NS  + T    V
Sbjct: 919  PEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKV 978

Query: 1192 EEPSINFTLRLPEFIL------VPANTDAYLTVEIPDE-TLDVTWYKK-KSVIEDTEKFT 1243
            E   I    R PEF++      V     A + V++  + T  + W+K  + ++ D ++  
Sbjct: 979  E---IEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVK 1035

Query: 1244 LISDVK-KRTLIIRKCTEDDQCEYTCVLLDAKSTT----------KLKVEVVEFPPKIVD 1292
             +S     + LII K T +D  EY  +  + + T+          KL+ +V E  P  V+
Sbjct: 1036 AVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVN 1095

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
              R+  ++ G  + L V +   P P+  W  +   ++       + D K   L I   E 
Sbjct: 1096 PMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGAPLQPSDRFTITCDGKKTELEINPCEG 1155

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPP----GKPNILEIDSSSINICWDEPENTG 1408
             DAG+Y+ R+ N  G         +     PP       ++ ++ +              
Sbjct: 1156 KDAGVYECRISNPLGEDSTRSTANVRKIFQPPSFIHAFKDLQQLPTFDAKFL-ARVSGVP 1214

Query: 1409 NSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-ASE 1466
               I +YV E   +   +   +K +       +++   + S  ++  AVN+   ++ A+ 
Sbjct: 1215 RPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAAN 1274

Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
             T   ++ K  K + P+  K + +         + T    G+P+P   W+ +G K+
Sbjct: 1275 LTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDKM 1330



 Score =  143 bits (346), Expect = 5e-32
 Identities = 240/1134 (21%), Positives = 442/1134 (38%), Gaps = 116/1134 (10%)

Query: 716  EGEASLPIVLKIK-TGEKEPPQVIEP-LKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
            E E+S   +L+ + T E  PP +I+  L    V + ++++   +    PR    W K+ K
Sbjct: 375  EKESSKADILERESTEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGK 434

Query: 774  PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            P+++   +  +S G+   + + K   ++DEGVYT    N  G   T   +TV+  T +  
Sbjct: 435  PLRSGERVRIESSGERFRMELSKII-IEDEGVYTCSFSNKLGEDMTEGYLTVQ--TVDEL 491

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEIISPSETITQNFDGE--N 887
              P FI   Q++ V    +    A  T +PVP ITWY + +EI S    +    D +  +
Sbjct: 492  RRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGS 551

Query: 888  IELVITNVD------SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
             +L  T V       S+ D+G+Y     N  G++   A + + +     ++ L     T 
Sbjct: 552  DKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFLNLLL--CPEIQELN-DVTTN 608

Query: 942  EGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX--DVGVI 997
             G+++  +   + +      W  + K +   +  +  ++ R              D G  
Sbjct: 609  VGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAY 668

Query: 998  KCIVKDQ--ETSTMLVVK--ETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWE 1050
            +   K+   E S   ++      P F   L    V+ KD + +E ++        ++ W 
Sbjct: 669  QVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLKWL 728

Query: 1051 R-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYSC----ILRDESCTAEVTVV 1103
            R + EI +  + K   ++ G+  +     T+    D G+ +C    I      + ++ V 
Sbjct: 729  RCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQ 788

Query: 1104 ELPPEIITRL-QNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK 1160
             + P  +  L ++ +V++G     + ++  G  +  + W+KDG +I    H ++ I    
Sbjct: 789  LITPSFVNLLPKSTEVDEGGCLELKAKID-GSPMPEISWYKDGEKIVPDEHTRIEILPDG 847

Query: 1161 QKLKIYDCDLD-DAGEYSCEVGNSK------CTAILTVEEPSINFTLRLPEFILV---PA 1210
                I DC    D G Y   + NS       C   +  E    +F+  L +  +V   P 
Sbjct: 848  TTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPL 907

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTCV 1269
              +A + V  P+   +V W+K    +  T++   I++ +    L I  C  +D   Y+  
Sbjct: 908  KLEAQV-VAFPNP--EVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMT 964

Query: 1270 ----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
                L +   T K+++E  E  P+ V   +   +  G    + V     P P  +W  N 
Sbjct: 965  VSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKNG 1024

Query: 1326 K-IIKKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            + I+   K  K  S+   S +L I+K    DAG Y++   N  G +  +  ++++ K   
Sbjct: 1025 EEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQS 1084

Query: 1384 P---GKPNILEIDSSSINICWDEPENTGNSTI------IYYVVEYQEIDTTEWISVK-NI 1433
                 KP  +      + +   +P N   S +      + +  +   +  ++  ++  + 
Sbjct: 1085 DVSEQKPGFVN-PMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGAPLQPSDRFTITCDG 1143

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
             KT+  I   +   +  +     N +       T    K+      Q P+     K++  
Sbjct: 1144 KKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIF-----QPPSFIHAFKDLQQ 1198

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX-----XXXXXXXXXXY 1548
             P  D +      GVP+P +TWY + K +      Y+ +                    Y
Sbjct: 1199 LPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVY 1258

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV-------TAVIEGIPP 1601
            KC A N  GE E +  + I  +       E      ++GD  +        TA + GIP 
Sbjct: 1259 KCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPE 1318

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-----V 1656
            P+  W+ NG+K+       +  +     + I  +    + KYT++ SN  G  S     +
Sbjct: 1319 PDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTADLI 1378

Query: 1657 EVTLKV------------YDKPSK-------PEGPVIMREISRESVTIEWKPPLDDGGLE 1697
              TL+             +DK  K        + P+I R + R  +T+ WKP +  G   
Sbjct: 1379 YETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRH-LTLSWKPSIPIGSRI 1437

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
               Y IE  E  +  W       R      I+ L    +Y FR+  +N  G S+
Sbjct: 1438 PVTYQIEMCELPDGDWFTARTGIRSC-VCDIRNLEPFRDYKFRIRVENKYGISD 1490



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 79/320 (24%), Positives = 145/320 (45%), Gaps = 20/320 (6%)

Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK----KRT 1252
            +F +RL E++ V  N     +  I +E  D  W  +  +I +  +FT I D +    +R 
Sbjct: 2131 DFPVRLREYMKVACNRSPGFSRTITEENFD--W--RTPIIRERRRFTDIMDEEIDDERRA 2186

Query: 1253 LIIRKCTEDD----QCEYTC-VLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305
             I R  + D+    + ++     LD  A++   L+ +     P   +  +   I+ G   
Sbjct: 2187 RINRYGSPDNFTLRRLKHELGTRLDSYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPA 2246

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLEN 1364
             L       P+P  +W  N  ++++    K + D    S L+    +  D G YK+   N
Sbjct: 2247 QLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARN 2306

Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
            + G   V   +     PS P  P ++++  + I + W +P++ GNS ++ Y ++Y+E D+
Sbjct: 2307 SLGQTVVRTRIVEAFVPSGPDSPELVDVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDS 2366

Query: 1425 TEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKIQS 1481
             +WI +  NI      I+NLK +++Y FR  A N +  S+    ++  K       K+Q 
Sbjct: 2367 IDWIDIASNIDHEFYLIRNLKADTTYNFRLAARNRIGWSEKGIPSKLIKTRLPGCPKVQI 2426

Query: 1482 PTVEKPLKNITTEPNEDIEL 1501
                K L+ + TE  ++I L
Sbjct: 2427 TQAMKHLQEL-TESGQEIVL 2445



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 3/155 (1%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            G P P + WYKN   ++      IT  ++  S++     K      Y + A N+ G + V
Sbjct: 2254 GSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTVV 2313

Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
               +     PS P+ P ++ ++S   + + WK P  DG   +  Y ++  E D+  WI +
Sbjct: 2314 RTRIVEAFVPSGPDSPELV-DVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSIDWIDI 2372

Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            A  + D E Y I+ L  +  Y FR+ A+N +G+SE
Sbjct: 2373 AS-NIDHEFYLIRNLKADTTYNFRLAARNRIGWSE 2406



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 77/293 (26%), Positives = 126/293 (43%), Gaps = 25/293 (8%)

Query: 1492 TTEPNED--IELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXX 1544
            +TE +E   +EL     G P P+++WY+DG+K+   + T      +              
Sbjct: 801  STEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPLD 860

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
               YK +  N  GE  + C V I+   +KP  + S ED+K    VG+   + A +   P 
Sbjct: 861  CGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIV--VGEPLKLEAQVVAFPN 918

Query: 1602 PEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            PEV W+KNG  L   KE Y I        +RI   +   +  Y++  SN+ G ++    +
Sbjct: 919  PEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKV 978

Query: 1661 KVYDKPSKPEGPVIMREIS-------RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            ++ +K  +PE  V ++ +S       +  V +  KP      L+  K   E+  PD  R 
Sbjct: 979  EIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKP---TPRLQWFKNG-EEIVPDGKR- 1033

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
            +K   +    +   I+K        ++VIA N  G S    +  +V K   DV
Sbjct: 1034 VKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDV 1086



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 10/174 (5%)

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKC 1550
            N +  L     G P+PK+T+Y + + +++        T   +               Y+ 
Sbjct: 1560 NHNCNLFWFVYGYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEA 1619

Query: 1551 IAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            +A N+HGE      + I + P  I    E I    ++G    +TA + G+P PE+ WYK+
Sbjct: 1620 VASNEHGEARQRVCLRIAEYPTFIHRPEETIVMIRRIGQ---LTARVTGVPYPEIKWYKD 1676

Query: 1610 GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
               L       I  KE  TS++ I +        Y++ A N AG+ S  V L V
Sbjct: 1677 WKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGSISCSVMLHV 1730



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 758  VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814
            V G P+P +T+  N++P+++        T +   T+   + + +DEG+Y   A N  G A
Sbjct: 1569 VYGYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEA 1628

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
                 + +       AE P FI+R +E  V  +   +L ARVT  P P I WY++ + ++
Sbjct: 1629 RQRVCLRI-------AEYPTFIHRPEETIVMIRRIGQLTARVTGVPYPEIKWYKDWKPLT 1681

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             S  I   F   +  L+I +     D G Y   A N AG  S
Sbjct: 1682 TSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGSIS 1723



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 47/140 (33%), Positives = 65/140 (46%), Gaps = 9/140 (6%)

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L I  + +  EG Y  VA N  GEA   + L+I     E P  I   +  IV      
Sbjct: 1602 ATLFINRMLERDEGLYEAVASNEHGEARQRVCLRIA----EYPTFIHRPEETIVMIRRIG 1657

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAE 808
             L+A+V G P P I W K+ KP+           + DT S+ I+    VKDEG+Y++ A 
Sbjct: 1658 QLTARVTGVPYPEIKWYKDWKPLTTSSRIRIEFKEPDT-SLLIISDTMVKDEGLYSVSAR 1716

Query: 809  NSEGIAETSAVITVEEPTEE 828
            N  G    S ++ VEE   E
Sbjct: 1717 NVAGSISCSVMLHVEENEHE 1736



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 37/121 (30%), Positives = 66/121 (54%), Gaps = 7/121 (5%)

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
            KE D   +++ A N++G ++   ++ V     A VPS P +P E+  V    ++  W  P
Sbjct: 2293 KEHDVGSYKVVARNSLGQTV-VRTRIVE----AFVPSGPDSP-ELVDVSDTEILVRWKQP 2346

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            + DG +P+L YN+  ++     W+++   +++   + IR+L  + TY  R+ ARN IG S
Sbjct: 2347 KHDGNSPVLCYNLQYKEGDSIDWIDIAS-NIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405

Query: 2051 E 2051
            E
Sbjct: 2406 E 2406



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 101/492 (20%), Positives = 188/492 (38%), Gaps = 32/492 (6%)

Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            PP I+     +  +     +   V+  + P+ + +W  + K ++  +  +     +   +
Sbjct: 394  PPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGERVRIESSGERFRM 453

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTI--LDKPSPPGKPNILE-IDSSSINICWD 1402
             + K+   D G+Y     N  G    E  +T+  +D+   P     L+ +D ++      
Sbjct: 454  ELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGMF 513

Query: 1403 EPENTGNST--IIYYVV--EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
            +   T +    I +Y    E    D+   I+V N   +    +   T S  +       E
Sbjct: 514  KAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGE 573

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
              +   ++  E         +  P +++ L ++TT   E +    I  G P+P +TW +D
Sbjct: 574  YTLKLKNKYGEAESNAFLNLLLCPEIQE-LNDVTTNVGESLAWQAIIKGNPKPDITWSKD 632

Query: 1519 GKKL-KTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKP 1571
            GK L K  +  +E     N+               Y+  A N  GE     ++    + P
Sbjct: 633  GKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGEASAQAILTPYSETP 692

Query: 1572 VIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--- 1626
            + +  +  + ++ K +   E+ V     GIP P + W +   ++  D  Y I  +E    
Sbjct: 693  IFSEILPKKPVECKDRSDVEFKVRC--SGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNN 750

Query: 1627 -TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVT 1684
              SV  I     S   K T  ASN  G++     L V    PS         E+  E   
Sbjct: 751  VESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLLPKSTEVD-EGGC 809

Query: 1685 IEWKPPLDDGGL-ELTKYAI-EKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRV 1741
            +E K  +D   + E++ Y   EK  PD +  I++  D    +   C+Q L  +C   +++
Sbjct: 810  LELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPL--DCG-AYKL 866

Query: 1742 IAQNPVGFSEAL 1753
            +  N  G   +L
Sbjct: 867  VINNSTGEQSSL 878



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 53/223 (23%), Positives = 88/223 (39%), Gaps = 27/223 (12%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATL 568
            P F+   +          +F  +V G PRP ITW+  +  I++    +++  D D    L
Sbjct: 1187 PSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGD-ACCL 1245

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             +++   +D+G + C A N  G A     L +   + + G                   I
Sbjct: 1246 YVKDCTYDDSGVYKCRAVNKGGEAECAANLTI---VDEIGK------------------I 1284

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
             +  PP+F K+     + +G        +  IPEPD  W   G+++   + I +  E  +
Sbjct: 1285 QKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDKMWQTDRIRMDQEGSL 1344

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
                  L I NV +   G YT+   N  GE S    L  +T E
Sbjct: 1345 LR----LTINNVDELDAGKYTLKISNPHGEDSCTADLIYETLE 1383



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 3/127 (2%)

Query: 478  NNYT-QYLQKKLNEKIDKLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            +N+T + L+ +L  ++D     E    S+++   P F EK + K   +G   Q  C   G
Sbjct: 2195 DNFTLRRLKHELGTRLDSYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPAQLACLAVG 2254

Query: 536  YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
             P+P I W++   +++ +   ++  D D  + L        D G++  VA+N+ G     
Sbjct: 2255 SPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTVVR 2314

Query: 596  TELIVEA 602
            T  IVEA
Sbjct: 2315 TR-IVEA 2320



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 17/188 (9%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ----VEGYPRPQITWFRQTAIIKPSQ 554
            E+P  +  + AP F   LR +H          C     V GYP+P++T++     I+   
Sbjct: 1534 ERPPHDNYAQAPRF---LRQEHDTQYGVKNHNCNLFWFVYGYPKPKMTYYFNDQPIESGG 1590

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
             +   Y  +  ATL I  +   D G +  VA N  G A     L I E P   H  E T+
Sbjct: 1591 RYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEARQRVCLRIAEYPTFIHRPEETI 1650

Query: 614  XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGE 672
                           + G+P      P+ ++  +   +    R+ +   EPD + L   +
Sbjct: 1651 VMIRRIGQLTAR---VTGVP-----YPEIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISD 1702

Query: 673  EIVPDENI 680
             +V DE +
Sbjct: 1703 TMVKDEGL 1710



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDM 688
            EG  P F +KP+ + ++EG    L C  V  P+P I W +K + +V + N I +  + D 
Sbjct: 2225 EGHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQW-YKNDMMVQETNRIKITEDQDG 2283

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
                S+L     K+   G+Y VVA N  G+
Sbjct: 2284 R---SILSFNPTKEHDVGSYKVVARNSLGQ 2310



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 9/114 (7%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            +++ ARN +G ++  T   +I      + P  P    VS++    + ++W +P+ +G SP
Sbjct: 2300 YKVVARNSLGQTVVRT---RIVEAFVPSGPDSPELVDVSDT---EILVRWKQPKHDGNSP 2353

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVS 1949
            +  Y +++K      W  I +     HE + I N+K      FR++A N +G S
Sbjct: 2354 VLCYNLQYKEGDSIDWIDIAS--NIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 21/81 (25%), Positives = 41/81 (50%)

Query: 528  QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
            Q   +V G P P+I W++    +  S   ++ + + + + L+I +   +D G ++  A+N
Sbjct: 1658 QLTARVTGVPYPEIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARN 1717

Query: 588  AAGFASSTTELIVEAPLSDHG 608
             AG  S +  L VE    ++G
Sbjct: 1718 VAGSISCSVMLHVEENEHEYG 1738



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 25/89 (28%), Positives = 41/89 (46%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P F  + Q   ++E    +L      +P P I WY+N+ ++  +  I    D +   ++ 
Sbjct: 2229 PFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILS 2288

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             N   E D G YK VA NS G++    R+
Sbjct: 2289 FNPTKEHDVGSYKVVARNSLGQTVVRTRI 2317



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%)

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGV 802
            + +G+   L+   VG+P+P I W KN+  V+    +    D D  SI    P K  D G 
Sbjct: 2240 IEEGKPAQLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGS 2299

Query: 803  YTLKAENSEG 812
            Y + A NS G
Sbjct: 2300 YKVVARNSLG 2309



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXXXARIQKLSINTTYQ 1836
            + +  + + W   + +G SP++ Y ++ K+ +   W             I+ L  +TTY 
Sbjct: 2334 VSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSIDWIDIASNIDHEFYLIRNLKADTTYN 2393

Query: 1837 FRIYARNEIGTS 1848
            FR+ ARN IG S
Sbjct: 2394 FRLAARNRIGWS 2405



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 62/281 (22%), Positives = 119/281 (42%), Gaps = 25/281 (8%)

Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDE-NEIIQEKQTLEELPKEDVPEQYTITPRKSSAQ 390
           K  + E+ E+++ L +  D V+ ++    +I++++Q+ + +  +  P +     ++SS  
Sbjct: 322 KAGEEEREEVDEELEALLDRVKRQRSVLGDILEKEQSRDNILGKGQPSETDSLEKESS-- 379

Query: 391 KIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDT 450
           K D I++  + ++   P  I  T  +     TV+   + V E  EA +L   +  +  D 
Sbjct: 380 KAD-ILERESTEESAPPHIIKSTLAD----KTVYETQTIVFEV-EATSLPRADAKWFKDG 433

Query: 451 SN-QDWWYVQKHLTEEKGWVPAQYLM--DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQS 507
              +    V+   + E+  +    ++  DE  YT     KL E  D    +    + ++ 
Sbjct: 434 KPLRSGERVRIESSGERFRMELSKIIIEDEGVYTCSFSNKLGE--DMTEGYLTVQTVDEL 491

Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN--- 564
             P F+E L+     +G +  F+      P P ITW+ +   I  S+D ++    DN   
Sbjct: 492 RRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIH-SEDSRLKITVDNKPG 550

Query: 565 -------VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598
                    TL + +   +D G +T   KN  G A S   L
Sbjct: 551 SDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFL 591



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 56/293 (19%), Positives = 113/293 (38%), Gaps = 37/293 (12%)

Query: 1508 VPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
            +P+    W++DGK L++ +     +   R               Y C   N  GE  T  
Sbjct: 422  LPRADAKWFKDGKPLRSGERVRIESSGERFRMELSKIIIEDEGVYTCSFSNKLGEDMTEG 481

Query: 1564 VVGIQ-----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DK 1617
             + +Q     ++P    + +D+   +  G   +  A+    P P++ WY  G+++ + D 
Sbjct: 482  YLTVQTVDELRRPKFIETLQDVDVAN--GKSGMFKAMFTADPVPDITWYFKGDEIHSEDS 539

Query: 1618 EYNITTKEK---------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
               IT   K         T  + + +  +  + +YT++  N  G +     L +   P  
Sbjct: 540  RLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFLNLLLCPEI 599

Query: 1669 PEGPVIMREISRE---SVTIEWKPPLD-----DGGL--ELTKYAIEKHEPDNNRWIKVAD 1718
             E   +   +         I+  P  D     DG +  +  +Y  E+ + +N   + + +
Sbjct: 600  QELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKE 659

Query: 1719 VDRDVE-TYCIQKLN----ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
            V+ D +  Y +   N     + + +    ++ P+ FSE L  +P+  K   DV
Sbjct: 660  VEIDDKGAYQVTAKNYLGEASAQAILTPYSETPI-FSEILPKKPVECKDRSDV 711


>UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n=2;
            Xenopus tropicalis|Rep: UPI00004DA303 UniRef100 entry -
            Xenopus tropicalis
          Length = 2690

 Score =  215 bits (525), Expect = 1e-53
 Identities = 259/1098 (23%), Positives = 437/1098 (39%), Gaps = 96/1098 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PPT   +     +     +LLEC+  AIP P I WL  G  ++  +   V +  D H  
Sbjct: 374  VPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRPLL--QRPGVQVIDDGH-- 429

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L+I   +    G YT  A N  G       + I            P K ++V +G  
Sbjct: 430  --YLQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTP-KQLMVNKGSL 486

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENS 810
            V +   V G P P++TW K+  P+   P          +TILK +     G Y   A N+
Sbjct: 487  VTMECVVSGKPSPSVTWLKDGYPLGNGPDLFFQNKGQQLTILKAQP-SHSGRYVCVAVNA 545

Query: 811  EGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
             G  +    + V+ P E  N +  L       ++    GT  +    T  P P ITW+RN
Sbjct: 546  AGQTDIKYEVFVQVPPELPNTQTELL-----NVSTSLHGTFTITCEATGIPPPVITWFRN 600

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            NE +SP E +     G  + +    +    D+G Y CV +N+AG++     V I V   +
Sbjct: 601  NEALSPRENVHLQSGGRVLRITHAQIQ---DAGHYTCVVTNTAGQAKKDFFVDILVPP-S 656

Query: 930  FVKHLQKSYETEEGKTVILECQTS-HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
                        EG++V L C+ S H      W  + + +   D   I  +G        
Sbjct: 657  IDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPDG--SELHIQ 714

Query: 988  XXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-------V 1038
                 +VG   CI  +   E S   +V   +   I    D E  E  + I+         
Sbjct: 715  SANVFNVGHYTCIAINSIAERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICE 774

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
             +      V W ++GE  K   N       GH   L I N    D G+Y+C++ +E   A
Sbjct: 775  ALGFPIPSVTWLKNGEPFKDSDN-LRLLPGGH--GLQILNAQEEDSGQYTCVVTNEVGEA 831

Query: 1099 ----EVTVVELPPEIITRLQNQKVN-KGNKATFEIELT---KGDAL----VRWFKDGSEI 1146
                EV V  +PP I     +Q V  K  K      LT   +  A+    + W+KDG  +
Sbjct: 832  IRNYEVKVF-IPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLL 890

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRL 1202
            + S  +Q+  DG  Q+L++    L D+G Y+C      G  +    + V++         
Sbjct: 891  ESSGGVQILSDG--QELQLQPIRLSDSGRYTCVATNVAGEDEKEFYVNVQDDDEEELTEH 948

Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
             E +     +    T  IP   L  TWYK   ++  ++   ++  ++ R L I       
Sbjct: 949  REVVATNPISLYCDTNAIPPPIL--TWYKDGQLLSSSDGVLIL--LEGRILQIPMAHAKH 1004

Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE-----REYRIKRGSDVTLLVDYQAFPQP 1317
              +YTC   +     +L  E+V   P ++  E     +E  +       L  D    P P
Sbjct: 1005 AGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPP 1064

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------- 1370
            +  W+ N   +   +  +  I ++  +L I  V+ +D   Y    EN  G A+       
Sbjct: 1065 SITWLRNGLTLSTAE--RYQILNEGKTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMV 1122

Query: 1371 VEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-I 1428
             E++ + +  P PP  +  +L I  S +  C  E E +  S ++  + + + +D+  W +
Sbjct: 1123 HELSFSSVRCPVPPHTRDYVLIIGKSIVLSC--EAEGS-PSPVVTSLKDGEPLDSGVWGV 1179

Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
            +++    ++  I  ++ + + R+R  A N +     SET + + ++ +   +    E P 
Sbjct: 1180 AIRG---SRLQITRVQQSHAGRYRCIAQNSI-----SETHKDFVLLVQVAPRIFGSEMPS 1231

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXXXXXXXXX 1541
            ++   E  ++++L C   G P P++ W++DG  L        +   T ++          
Sbjct: 1232 EHSVPE-KQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQ 1290

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C+A N+ GE     V+ I   PV+  S    +     G     T    G P 
Sbjct: 1291 ASDSGRYTCVARNNAGEDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPL 1350

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P + W K+G  L  + + N+      + + ++ ++   S  Y+  A N AG  S    L 
Sbjct: 1351 PSLSWEKDGQPL--NLQSNLLPNGLGTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLT 1408

Query: 1662 VYDKPSKPEGPVIMREIS 1679
            V + P + EGP +  E+S
Sbjct: 1409 VLE-PPRIEGPALPTEVS 1425



 Score =  199 bits (486), Expect = 6e-49
 Identities = 242/1070 (22%), Positives = 420/1070 (39%), Gaps = 78/1070 (7%)

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            +GS++ L C+   +P P + W   G+ + P +      E        VL++   +   +G
Sbjct: 17   DGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGG-----QVLQLNGTRLSDQG 71

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESVILSAQVVGNPRP 764
             Y  +A N  G+      L++ T    PP +    ++  V      +V L  +   +P P
Sbjct: 72   RYQCLAFNHAGQQVKDFNLRVHT----PPTIWASNETTEVASLLHGTVELRCEARASPVP 127

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             ITW K+ +P+ +    +  +      L    + D G YT +A N+ G AE S  + V  
Sbjct: 128  GITWFKDKRPIVSSSRATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYRLEVYV 187

Query: 825  PTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            P      P + I    E +TV     + L    T  P P+I W RNN  +S  + +    
Sbjct: 188  P------PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDGVEVLN 241

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
              +  +L I +  S  DSG+Y+CVASN+AG +     + ++V  ++  +         E+
Sbjct: 242  GVQGPKLQIESAKSS-DSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATFLVNEQ 300

Query: 943  GKTVILECQTSHT--VSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
               V LEC  +     +  W  ++  +S  +   +I+++GR            D G+  C
Sbjct: 301  ---VWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGR--ILSLRAAHVSDSGIYSC 355

Query: 1000 IVKDQ--ETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVV-WERDGEI 1055
            +  +   E S  + ++  +P  I   + +  +      +LE +  +    ++ W +DG  
Sbjct: 356  VAVNPAGEDSHHIALQVFVPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRP 415

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEIITR 1112
            +  +      +  GH   L I    + D G Y+C   +++   E     ++   P I   
Sbjct: 416  LLQRPGVQVIDD-GHY--LQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGS 472

Query: 1113 LQNQK---VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
                K   VNKG+  T E  ++ K    V W KDG  +   N   L    K Q+L I   
Sbjct: 473  SNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKDGYPL--GNGPDLFFQNKGQQLTILKA 530

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP--EFILVPANTDAYLTVEIPDETLD 1226
                +G Y C   N+     +   E  +     LP  +  L+  +T  + T  I  E   
Sbjct: 531  QPSHSGRYVCVAVNAAGQTDIKY-EVFVQVPPELPNTQTELLNVSTSLHGTFTITCEATG 589

Query: 1227 -----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
                 +TW++    +   E   L S    R L I      D   YTCV+ +     K   
Sbjct: 590  IPPPVITWFRNNEALSPRENVHLQSG--GRVLRITHAQIQDAGHYTCVVTNTAGQAKKDF 647

Query: 1282 EVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
             V    P  +D E   + R+  G  VTL       P+P   W+ +S+ ++       S D
Sbjct: 648  FVDILVPPSIDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPD 707

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
               + L I+     + G Y     N+         VT+L  P+  G P   E +   I I
Sbjct: 708  --GSELHIQSANVFNVGHYTCIAINSIAERSRSYIVTVLVSPTISG-PLDDEANEDVIVI 764

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-----QTSIQNLKTNSSYRFRAY 1454
              + P +     + + +     +   E     +  +         I N +   S ++   
Sbjct: 765  V-NNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQEEDSGQYTCV 823

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
              NEV  +  +   + + +    K   P  +  +K + T+ N  + L C    VP+P + 
Sbjct: 824  VTNEVGEAIRNYEVKVF-IPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQAVPKPTLH 882

Query: 1515 WYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
            WY+DG+ L+++       +                Y C+A N  GE E    V +Q    
Sbjct: 883  WYKDGQLLESSGGVQILSDGQELQLQPIRLSDSGRYTCVATNVAGEDEKEFYVNVQDD-- 940

Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
                 E++ +  +V     ++   +   IPPP + WYK+G  L +     I  + +  ++
Sbjct: 941  ---DEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEGR--IL 995

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREIS 1679
            +I      H+ KYT EA+N AG   +   L V   P  K E   +++E+S
Sbjct: 996  QIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVS 1045



 Score =  190 bits (463), Expect = 4e-46
 Identities = 223/967 (23%), Positives = 376/967 (38%), Gaps = 80/967 (8%)

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-------SITILK 793
            L+ M  R G  V L  +  G PRP + W K+ +P   LP    GD H        +  L 
Sbjct: 10   LQDMTARDGSEVELHCKASGVPRPQVEWTKDGQP---LPP---GDAHIQLTEGGQVLQLN 63

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
              ++ D+G Y   A N  G       + V  P    A      N   E+     GT++L 
Sbjct: 64   GTRLSDQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWAS-----NETTEVASLLHGTVELR 118

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                 +PVP ITW+++   I  S   T    G +++L    +    D G Y C A+N+AG
Sbjct: 119  CEARASPVPGITWFKDKRPIVSSSRATYREGGRSLQLSRVLLS---DVGTYTCRATNNAG 175

Query: 914  KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD 971
             +    R+ + V     +    +         + L C  +   T + +W  N   +S  D
Sbjct: 176  TAEKSYRLEVYVPPKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHED 235

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIPEFIRKLQDFEV 1028
              E++   +            D G  +C+  +   ST L   ++    P  +  +     
Sbjct: 236  GVEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATF 295

Query: 1029 KEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
               +   LE          ++W +D   +          ++G I  L +R   V D G Y
Sbjct: 296  LVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGRI--LSLRAAHVSDSGIY 353

Query: 1088 SCIL---RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDG 1143
            SC+      E        V +PP I+    N  +        E + T     L+ W KDG
Sbjct: 354  SCVAVNPAGEDSHHIALQVFVPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDG 413

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINF 1198
              +     +Q+  DG    L+I    L DAG Y+CE  N      K   ++   +P I  
Sbjct: 414  RPLLQRPGVQVIDDG--HYLQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAG 471

Query: 1199 TLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
            +   P+ ++V  N  + +T+E       +  VTW K    + +     L    K + L I
Sbjct: 472  SSNTPKQLMV--NKGSLVTMECVVSGKPSPSVTWLKDGYPLGNGP--DLFFQNKGQQLTI 527

Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDYQA 1313
             K        Y CV ++A   T +K EV V+ PP++ + + E   +      T  +  +A
Sbjct: 528  LKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTELLNVSTSLHGTFTITCEA 587

Query: 1314 --FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
               P P   W  N++ +   ++    + S    L I   +  DAG Y   + N  G A  
Sbjct: 588  TGIPPPVITWFRNNEALSPRENV--HLQSGGRVLRITHAQIQDAGHYTCVVTNTAGQAKK 645

Query: 1372 EMNVTILDKPSPPGK-PNILEI-DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
            +  V IL  PS  G+  N L + +  S+ +      +     +I ++ + Q + + + + 
Sbjct: 646  DFFVDILVPPSIDGEDDNDLRVPEGQSVTLSCKVSGHP--KPLITWLRDSQPVQSGDEVL 703

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
            + +   ++  IQ+    +   +   A+N +     +E +  Y V   T + SPT+  PL 
Sbjct: 704  I-SPDGSELHIQSANVFNVGHYTCIAINSI-----AERSRSYIV---TVLVSPTISGPLD 754

Query: 1490 NITTEP-----NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX 1542
            +   E      N    L C   G P P VTW ++G+  K +                   
Sbjct: 755  DEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQE 814

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDI---KQKHKVGDEWLVTAVIE 1597
                 Y C+  N+ GE   +  V +   PVI     ++D+   + K KV     +    +
Sbjct: 815  EDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQ 874

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
             +P P + WYK+G  LE+     I +  +   ++++ ++ S S +YT  A+N AG    E
Sbjct: 875  AVPKPTLHWYKDGQLLESSGGVQILSDGQE--LQLQPIRLSDSGRYTCVATNVAGEDEKE 932

Query: 1658 VTLKVYD 1664
              + V D
Sbjct: 933  FYVNVQD 939



 Score =  190 bits (462), Expect = 5e-46
 Identities = 230/1054 (21%), Positives = 424/1054 (40%), Gaps = 87/1054 (8%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            + C    IP P I W    E + P EN+ +           VL+IT+ +    G YT V 
Sbjct: 583  ITCEATGIPPPVITWFRNNEALSPRENVHLQSGG------RVLRITHAQIQDAGHYTCVV 636

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
             N  G+A     + I      PP +  E    + V +G+SV LS +V G+P+P ITW ++
Sbjct: 637  TNTAGQAKKDFFVDILV----PPSIDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRD 692

Query: 772  NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            ++PV++          S   ++   V + G YT  A NS  IAE S    V         
Sbjct: 693  SQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIAINS--IAERSRSYIVTVLVSPTIS 750

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
             PL     +++ V       L+      P+PS+TW +N E    S+ +     G  ++++
Sbjct: 751  GPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQIL 810

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI---- 947
              N   E DSG Y CV +N  G++     V + +  V       +    +E KT +    
Sbjct: 811  --NAQEE-DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSL 867

Query: 948  -LECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
             L+C++      +  WY + + +      +I+ +G+            D G   C+  + 
Sbjct: 868  TLQCESQAVPKPTLHWYKDGQLLESSGGVQILSDGQELQLQPIRLS--DSGRYTCVATN- 924

Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKE-----KDVAILEVEINSETADV-----VWERDGE 1054
                  V  E   EF   +QD + +E     + VA   + +  +T  +      W +DG+
Sbjct: 925  ------VAGEDEKEFYVNVQDDDEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQ 978

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPP---- 1107
            ++          + G I  L I        G+Y+C   +E+    +    VV  PP    
Sbjct: 979  LLSSSDGVLILLE-GRI--LQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKG 1035

Query: 1108 EIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            E+   +Q   V     A    + +      + W ++G  +  +   Q+  +GK   L+I+
Sbjct: 1036 EVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLSTAERYQILNEGKT--LQIH 1093

Query: 1167 DCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFT-LRLP------EFILVPANTDAYLT 1217
               + D   Y C   N    A  + T+    ++F+ +R P      +++L+   +   L+
Sbjct: 1094 SVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRDYVLIIGKS-IVLS 1152

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             E       V    K     D+  + +   ++   L I +  +     Y C+  ++ S T
Sbjct: 1153 CEAEGSPSPVVTSLKDGEPLDSGVWGVA--IRGSRLQITRVQQSHAGRYRCIAQNSISET 1210

Query: 1278 -KLKVEVVEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCK 1332
             K  V +V+  P+I   E   E+ +    +V L    +  P P   W    N   +    
Sbjct: 1211 HKDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVP 1270

Query: 1333 HTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
            +T  ++  +  + L ++ V+ +D+G Y     NN G       + IL  P      +  E
Sbjct: 1271 NTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLNILGLPVLERSESTEE 1330

Query: 1392 IDS-SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
            + +    ++ +    +      + +  + Q ++    + + N   T+  +++++   S  
Sbjct: 1331 VTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNL-LPNGLGTRLHLESVRALDSGI 1389

Query: 1451 FRAYAVNEVDISDASETTEYYK--VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
            +   AVN      A   ++++   V++  +I+ P +   +  I   P   +EL C   GV
Sbjct: 1390 YSCIAVNA-----AGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSP---LELACTATGV 1441

Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            P P+++W +DG+ L        N                Y C+A +  G    +  V ++
Sbjct: 1442 PTPEISWEKDGRPLSHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMK 1501

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
              P +  S E       VG + ++   +E  PPP + WY+    L+ D    + +K +  
Sbjct: 1502 VPPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDIPLQTDGRVQVLSKGR-- 1559

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             ++I  L+ S S +YT  ASN AG +S+  T+++
Sbjct: 1560 YVQIHSLRPSDSGEYTCIASNPAGRTSLHFTVEI 1593



 Score =  170 bits (413), Expect = 4e-40
 Identities = 254/1189 (21%), Positives = 460/1189 (38%), Gaps = 128/1189 (10%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            DGS V+  C+  G PRPQ+ W +    + P        +   V  L +      D G + 
Sbjct: 17   DGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQV--LQLNGTRLSDQGRYQ 74

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            C+A N AG       L V  P +   S  T             A +L G           
Sbjct: 75   CLAFNHAGQQVKDFNLRVHTPPTIWASNET----------TEVASLLHG----------- 113

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
                    + L C   A P P I W FK +  +   + +   E    +  S + +++V  
Sbjct: 114  -------TVELRCEARASPVPGITW-FKDKRPIVSSSRATYREGGRSLQLSRVLLSDV-- 163

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVG 760
               GTYT  A N  G A     L++      PP+V+  E  + + V   + + LS    G
Sbjct: 164  ---GTYTCRATNNAGTAEKSYRLEVYV----PPKVVIGEGSEHVTVTANDPLDLSCHATG 216

Query: 761  NPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             P PTI W +NN  +         +G       ++  K  D G Y   A N+ G  E   
Sbjct: 217  YPTPTIQWLRNNHSLSHEDGVEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQY 276

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             + V      N  P + ++     T      + L    T  P P+I W ++   +S +  
Sbjct: 277  NLLV------NVAPRI-VSMMDFATFLVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIA 329

Query: 879  ITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
              Q  + G  + L   +V    DSG Y CVA N AG+ SH   + + V      + L  S
Sbjct: 330  GLQIMEQGRILSLRAAHVS---DSGIYSCVAVNPAGEDSHHIALQVFVPPTIMGEELNSS 386

Query: 938  YETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                +   ++LECQ++        W  + + +      ++I +G             D G
Sbjct: 387  IAVNQ--PLLLECQSTAIPPPLITWLKDGRPLLQRPGVQVIDDGH--YLQIDQAQLRDAG 442

Query: 996  VIKCIVK------DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVV 1048
               C         ++  + ++  +  I       +   V +  +  +E  ++ + +  V 
Sbjct: 443  RYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTPKQLMVNKGSLVTMECVVSGKPSPSVT 502

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVEL 1105
            W +DG  +    + + F+ +G  ++L I        G Y C+  + +   ++     V++
Sbjct: 503  WLKDGYPLGNGPDLF-FQNKG--QQLTILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQV 559

Query: 1106 PPEI---ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            PPE+    T L N   +     T   E T     ++ WF++   +    ++ L   G+  
Sbjct: 560  PPELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRNNEALSPRENVHLQSGGR-- 617

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYL 1216
             L+I    + DAG Y+C V N+   A     +  +  PSI+        + VP      L
Sbjct: 618  VLRITHAQIQDAGHYTCVVTNTAGQAKKDFFVDILVPPSIDG--EDDNDLRVPEGQSVTL 675

Query: 1217 TVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--A 1273
            + ++       +TW +    ++  ++  +  D  +  L I+     +   YTC+ ++  A
Sbjct: 676  SCKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSE--LHIQSANVFNVGHYTCIAINSIA 733

Query: 1274 KSTTKLKVEVVEFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            + +    V V+  P    P   +   +  +   +  +L+ +   FP P+  W+ N +  K
Sbjct: 734  ERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFK 793

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNV---TILDKPSPP 1384
               + +  +      L I   +  D+G Y   + N  G A  + E+ V    ++ +  P 
Sbjct: 794  DSDNLR--LLPGGHGLQILNAQEEDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPH 851

Query: 1385 GKPNILEID---SSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
                I E+    +SS+ + C  E +     T+ +Y  + Q ++++  + + +    +  +
Sbjct: 852  QDVGIKEVKTKVNSSLTLQC--ESQAVPKPTLHWY-KDGQLLESSGGVQILS-DGQELQL 907

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            Q ++ + S R+   A N        +  E+Y  +++   +  T  + +  + T P   I 
Sbjct: 908  QPIRLSDSGRYTCVATNVA----GEDEKEFYVNVQDDDEEELTEHREV--VATNP---IS 958

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            L C    +P P +TWY+DG+ L ++       E R               Y C A N+ G
Sbjct: 959  LYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEGR-ILQIPMAHAKHAGKYTCEATNEAG 1017

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            E      + +   PV+    +++ Q+  V       +     GIPPP + W +NG  L  
Sbjct: 1018 EDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLST 1077

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             + Y I  + KT  ++I  ++ S    Y   A N AG +    TL V++
Sbjct: 1078 AERYQILNEGKT--LQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHE 1124



 Score =  164 bits (399), Expect = 2e-38
 Identities = 231/1079 (21%), Positives = 426/1079 (39%), Gaps = 94/1079 (8%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            S  PK   V++GS + +EC +   P P + WL  G  +    ++    +         L 
Sbjct: 473  SNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKDGYPLGNGPDLFFQNKGQQ------LT 526

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            I   +    G Y  VAVN  G+  +   + ++   + P    E L       G   I + 
Sbjct: 527  ILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTELLNVSTSLHGTFTI-TC 585

Query: 757  QVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            +  G P P ITW +NN+   P + +  +S G    IT     +++D G YT    N+ G 
Sbjct: 586  EATGIPPPVITWFRNNEALSPRENVHLQSGGRVLRIT---HAQIQDAGHYTCVVTNTAGQ 642

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A+    + +  P   + E         ++ V E  ++ L  +V+ +P P ITW R+++ +
Sbjct: 643  AKKDFFVDILVPPSIDGEDD------NDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPV 696

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
               + +  + DG  + +   NV    + G Y C+A NS  + S    VT+ V        
Sbjct: 697  QSGDEVLISPDGSELHIQSANV---FNVGHYTCIAINSIAERSRSYIVTVLVSPTISGPL 753

Query: 934  LQKSYE-----TEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
              ++ E          ++I E       S  W  N +     D+  ++  G         
Sbjct: 754  DDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQ 813

Query: 989  XXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK---LQDF---EVKEKDVAILEVEI 1040
                D G   C+V ++  E      VK  IP  I++    QD    EVK K  + L ++ 
Sbjct: 814  EE--DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQC 871

Query: 1041 NSETAD---VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
             S+      + W +DG++++           G  ++L ++   + D G Y+C+  + +  
Sbjct: 872  ESQAVPKPTLHWYKDGQLLE-SSGGVQILSDG--QELQLQPIRLSDSGRYTCVATNVAGE 928

Query: 1098 AE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHI 1152
             E    V V +   E +T  ++++V   N  +   +       ++ W+KDG  +  S+ +
Sbjct: 929  DEKEFYVNVQDDDEEELT--EHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGV 986

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFI 1206
             + ++G+   L+I       AG+Y+CE     G  +    L V  P +       L + +
Sbjct: 987  LILLEGRI--LQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEV 1044

Query: 1207 LVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             V  N  A L  +   IP  +  +TW +    +   E++ ++++ K  TL I      D 
Sbjct: 1045 SVIYNQTAELHCDASGIPPPS--ITWLRNGLTLSTAERYQILNEGK--TLQIHSVQVSDI 1100

Query: 1264 CEYTCVLLD----AKSTTKLKVEVVEFPP---KIVDYEREYRIKRGSDVTLLVDYQAFPQ 1316
              Y CV  +    A+    L V  + F      +  + R+Y +  G  + L  + +  P 
Sbjct: 1101 DSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRDYVLIIGKSIVLSCEAEGSPS 1160

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMN 1374
            P    + + K  +        +  + + L I +V+ + AG Y+   +N+    H D  + 
Sbjct: 1161 PV---VTSLKDGEPLDSGVWGVAIRGSRLQITRVQQSHAGRYRCIAQNSISETHKDFVLL 1217

Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NI 1433
            V +  +      P+   +          + E T    I+++  +   +D T   +   N+
Sbjct: 1218 VQVAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQILWFK-DGNPLDVTLVPNTSGNL 1276

Query: 1434 TKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
            TK   +   +++++ + S R+   A N     +A E T  Y V+    +      +  + 
Sbjct: 1277 TKQDGNFLVLRSVQASDSGRYTCVARN-----NAGEDTRVY-VLNILGLPVLERSESTEE 1330

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX--Y 1548
            +T      +  TC   G P P ++W +DG+ L        N                  Y
Sbjct: 1331 VTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVRALDSGIY 1390

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
             CIA N  G V     + + + P I       +          +     G+P PE+ W K
Sbjct: 1391 SCIAVNAAGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSPLELACTATGVPTPEISWEK 1450

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +G  L +    ++ T+  T V+RI+ +K   +  Y   A++TAG  S    +++   PS
Sbjct: 1451 DGRPLSHP---DLLTRNGT-VLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMKVPPS 1505



 Score =  128 bits (308), Expect = 2e-27
 Identities = 184/824 (22%), Positives = 308/824 (37%), Gaps = 64/824 (7%)

Query: 599  IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECR 656
            I  A + D G     V             DIL  +PP+   +      V EG  + L C+
Sbjct: 621  ITHAQIQDAGHYTCVVTNTAGQAKKDFFVDIL--VPPSIDGEDDNDLRVPEGQSVTLSCK 678

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +   P+P I WL   + +   + + ++ +       S L I +   F  G YT +A+N  
Sbjct: 679  VSGHPKPLITWLRDSQPVQSGDEVLISPDG------SELHIQSANVFNVGHYTCIAINSI 732

Query: 717  GEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
             E S   ++ +        P   E  + +IV       L  + +G P P++TW KN +P 
Sbjct: 733  AERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPF 792

Query: 776  KALPT-KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            K     +     H + IL  ++ +D G YT    N  G A  +  + V  P     + P 
Sbjct: 793  KDSDNLRLLPGGHGLQILNAQE-EDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPH 851

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
                 +E+  K   ++ L       P P++ WY++ +++  S  +    DG+ ++L    
Sbjct: 852  QDVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLLESSGGVQILSDGQELQLQPIR 911

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
            +    DSG Y CVA+N AG+      V +  +     + L +  E      + L C T+ 
Sbjct: 912  LS---DSGRYTCVATNVAGEDEKEFYVNVQDDD---EEELTEHREVVATNPISLYCDTNA 965

Query: 955  TVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML-- 1010
                   WY + + +S  D   I+ EGR              G   C   ++     L  
Sbjct: 966  IPPPILTWYKDGQLLSSSDGVLILLEGR--ILQIPMAHAKHAGKYTCEATNEAGEDRLHY 1023

Query: 1011 -VVKETIP----EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYD 1064
             +V  T P    E    +Q+  V     A L  + +      + W R+G  +   + +Y 
Sbjct: 1024 ELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLSTAE-RYQ 1082

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-----------VTVVELPPEIITRL 1113
                G  + L I +  V D   Y C+  + +  AE            + V  P    TR 
Sbjct: 1083 ILNEG--KTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRD 1140

Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
                + K    + E E      +V   KDG  +  S    + I G   +L+I       A
Sbjct: 1141 YVLIIGKSIVLSCEAE-GSPSPVVTSLKDGEPLD-SGVWGVAIRG--SRLQITRVQQSHA 1196

Query: 1174 GEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DV 1227
            G Y C   NS     K   +L    P I F   +P    VP   +  L  +        +
Sbjct: 1197 GRYRCIAQNSISETHKDFVLLVQVAPRI-FGSEMPSEHSVPEKQEVKLECKTEGTPAPQI 1255

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEV 1283
             W+K  + ++ T       ++ K+    L++R     D   YTCV   +A   T++ V  
Sbjct: 1256 LWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLN 1315

Query: 1284 VEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            +   P +   E   E    +G+ VT   +    P P+  W  + + +    +  P  +  
Sbjct: 1316 ILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLP--NGL 1373

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
               L ++ V   D+GIY     N  G      ++T+L+ P   G
Sbjct: 1374 GTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVLEPPRIEG 1417



 Score =   99 bits (238), Expect = 7e-19
 Identities = 145/662 (21%), Positives = 252/662 (38%), Gaps = 47/662 (7%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            I L C   AIP P + W   G+ +   + + + +E        +L+I        G YT 
Sbjct: 957  ISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEG------RILQIPMAHAKHAGKYTC 1010

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
             A N  GE  L   L + T      +V E ++ + V   ++  L     G P P+ITW +
Sbjct: 1011 EATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLR 1070

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            N   +         +      +   +V D   Y   AEN  G AE    + V E +  + 
Sbjct: 1071 NGLTLSTAERYQILNEGKTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSV 1130

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
              P+  +    + +  K +I L      +P P +T  ++ E   P ++           L
Sbjct: 1131 RCPVPPHTRDYVLIIGK-SIVLSCEAEGSPSPVVTSLKDGE---PLDSGVWGVAIRGSRL 1186

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
             IT V     +G Y+C+A NS  ++     + + V    F   +   +   E + V LEC
Sbjct: 1187 QITRVQQS-HAGRYRCIAQNSISETHKDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLEC 1245

Query: 951  QTSHTVSTK--WYH--NKKEISGMDHRE-IIQEGRXXXXXXXXXXXXDVGVIKCIVKD-- 1003
            +T  T + +  W+   N  +++ + +    + +              D G   C+ ++  
Sbjct: 1246 KTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNA 1305

Query: 1004 -QETSTMLVVKETIPEFIRKLQDFEV---KEKDVAILEVEINSETADVVWERDGEIIKPK 1059
             ++T   ++    +P   R     EV   K   V        +    + WE+DG+ +  +
Sbjct: 1306 GEDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQ 1365

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELPPEIITRLQN 1115
             N       G   +L++ +    D G YSCI  + +        +TV+E PP I      
Sbjct: 1366 SNLLP---NGLGTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVLE-PPRIEGPALP 1421

Query: 1116 QKVNKGNKATFEIELTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
             +V+    +  E+  T        + W KDG  +  S+   LT +G    L+I     +D
Sbjct: 1422 TEVSIIADSPLELACTATGVPTPEISWEKDGRPL--SHPDLLTRNGTV--LRIERVKAED 1477

Query: 1173 AGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLD 1226
            AG Y C   +     S+ T +     PS+  +   P  + V       L  ++  D    
Sbjct: 1478 AGIYVCVATSTAGRDSRATWVRMKVPPSVVGSTE-PRSLAVSVGGQLVLECKVEADPPPT 1536

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            + WY+    ++   +  ++S  K R + I      D  EYTC+  +    T L    VE 
Sbjct: 1537 IQWYRGDIPLQTDGRVQVLS--KGRYVQIHSLRPSDSGEYTCIASNPAGRTSLHF-TVEI 1593

Query: 1287 PP 1288
             P
Sbjct: 1594 QP 1595



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 90/380 (23%), Positives = 155/380 (40%), Gaps = 25/380 (6%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI----VPDENISVAIESDMHMYC 692
            S+ P    V E  ++ LEC+    P P I W   G  +    VP+ + ++  +       
Sbjct: 1227 SEMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDG----- 1281

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            + L + +V+    G YT VA N  GE +   VL I        +  E  + +   +G SV
Sbjct: 1282 NFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLNILG--LPVLERSESTEEVTAIKGASV 1339

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              + +  G P P+++W K+ +P+            +   L+  +  D G+Y+  A N+ G
Sbjct: 1340 TFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVRALDSGIYSCIAVNAAG 1399

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
                   +TV EP     E P       E+++     ++L    T  P P I+W ++   
Sbjct: 1400 RVSKHFHLTVLEPPR--IEGPALPT---EVSIIADSPLELACTATGVPTPEISWEKDGRP 1454

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +S  + +T+N       L I  V +E D+G Y CVA+++AG+ S    V + V       
Sbjct: 1455 LSHPDLLTRN----GTVLRIERVKAE-DAGIYVCVATSTAGRDSRATWVRMKVPPSVVGS 1509

Query: 933  HLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
               +S     G  ++LEC  +     + +WY     +      +++ +GR          
Sbjct: 1510 TEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDIPLQTDGRVQVLSKGR--YVQIHSLR 1567

Query: 991  XXDVGVIKCIVKDQETSTML 1010
              D G   CI  +    T L
Sbjct: 1568 PSDSGEYTCIASNPAGRTSL 1587



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 99/431 (22%), Positives = 178/431 (41%), Gaps = 60/431 (13%)

Query: 508  MAP-IFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            +AP IF  ++  +H+ P+   V+ EC+ EG P PQI                +++ D N 
Sbjct: 1220 VAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQI----------------LWFKDGNP 1263

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
              + +    P  +G  T   K    F      ++     SD G    V            
Sbjct: 1264 LDVTL---VPNTSGNLT---KQDGNFL-----VLRSVQASDSGRYTCVARNNAGEDTRVY 1312

Query: 626  ADILEGIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
               + G+P    S+  +     +G+ +   C     P P ++W   G+ +    N+   +
Sbjct: 1313 VLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNL---L 1369

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKS 743
             + +    + L + +V+    G Y+ +AVN  G  S    L +     EPP++  P L +
Sbjct: 1370 PNGLG---TRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVL----EPPRIEGPALPT 1422

Query: 744  MIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800
             +    +S + L+    G P P I+W K+ +P+    +  D  T + T+L+ ++VK  D 
Sbjct: 1423 EVSIIADSPLELACTATGVPTPEISWEKDGRPL----SHPDLLTRNGTVLRIERVKAEDA 1478

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEE--NAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            G+Y   A ++ G    +  + ++ P     + EP       + + V   G + L  +V  
Sbjct: 1479 GIYVCVATSTAGRDSRATWVRMKVPPSVVGSTEP-------RSLAVSVGGQLVLECKVEA 1531

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            +P P+I WYR +  +     +     G  +++         DSG+Y C+ASN AG++S  
Sbjct: 1532 DPPPTIQWYRGDIPLQTDGRVQVLSKGRYVQIHSLRPS---DSGEYTCIASNPAGRTSLH 1588

Query: 919  ARVTIDVEKVT 929
              V I     T
Sbjct: 1589 FTVEIQPHSAT 1599



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 11/208 (5%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXXXX 1544
            L+++T     ++EL C   GVP+P+V W +DG+ L    A     E              
Sbjct: 10   LQDMTARDGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQVLQLNGTRLSD 69

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y+C+AFN  G+      + +   P I  SNE  +    +     +       P P +
Sbjct: 70   QGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHGTVELRCEARASPVPGI 129

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W+K+   + +      T +E    +++  +  S    YT  A+N AGT+     L+VY 
Sbjct: 130  TWFKDKRPIVSSS--RATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYRLEVYV 187

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLD 1692
             P      V++ E S E VT+    PLD
Sbjct: 188  PPK-----VVIGEGS-EHVTVTANDPLD 209



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 13/191 (6%)

Query: 476 DENNYTQYLQKKLNEKID--KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           D   YT  +  ++ E I   ++ VF  P  +     P     ++   T   S++  +C+ 
Sbjct: 816 DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDD--PHQDVGIKEVKTKVNSSLTLQCES 873

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
           +  P+P + W++   +++ S   Q+  D      L ++ +   D+G +TCVA N AG   
Sbjct: 874 QAVPKPTLHWYKDGQLLESSGGVQILSDGQE---LQLQPIRLSDSGRYTCVATNVAG--E 928

Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP---TFSKKPKAQYVDEGSD 650
              E  V     D   E+T                   IPP   T+ K  +     +G  
Sbjct: 929 DEKEFYVNVQ-DDDEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGVL 987

Query: 651 ILLECRLVAIP 661
           ILLE R++ IP
Sbjct: 988 ILLEGRILQIP 998



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 9/95 (9%)

Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           P+G +V   C+V G+P+P ITW R +  ++ S D  +   D +   +    VF  + G +
Sbjct: 668 PEGQSVTLSCKVSGHPKPLITWLRDSQPVQ-SGDEVLISPDGSELHIQSANVF--NVGHY 724

Query: 582 TCVAKNAAGFASST---TELI---VEAPLSDHGSE 610
           TC+A N+    S +   T L+   +  PL D  +E
Sbjct: 725 TCIAINSIAERSRSYIVTVLVSPTISGPLDDEANE 759


>UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to
            OTTHUMP00000065631; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to OTTHUMP00000065631
            - Strongylocentrotus purpuratus
          Length = 3664

 Score =  214 bits (522), Expect = 3e-53
 Identities = 251/1069 (23%), Positives = 440/1069 (41%), Gaps = 86/1069 (8%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            T SK P    V +   I L+C +  A P P I W +KG+E +  +  +V I+ D  +   
Sbjct: 2359 TGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKW-YKGDETLTGQEEAVTIK-DQGI--- 2413

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESV 752
             L+I +V     G Y   A N  G AS+   + ++      P ++      +   Q   +
Sbjct: 2414 TLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQV----TPSILNGQDEYLTTVQNIDI 2469

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSE 811
             L  +  GNP PTITW ++NKP++   +    G+  S+ I  P+   D G Y   A N+ 
Sbjct: 2470 TLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQHT-DSGGYVCVASNNI 2528

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G A  +  + V+ P + + +  +       +T+  + ++ L  +    P P+I+W ++N 
Sbjct: 2529 GYAIKNFHLVVKIPPKTSTQQEV-------VTIGLRQSVTLRCQAAGFPAPTISWRKDNL 2581

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             I P  T   +       L I N   E DSG Y C+ASN  G+ S    + +    +   
Sbjct: 2582 PI-PLSTRAFSISSNGGSLTI-NSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPIILG 2639

Query: 932  K---HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXX 986
            +   +  +  +  EG  + L C T+     +  W+ + + +S  +++ I  +G       
Sbjct: 2640 ELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPPEYK-IKDDG---TLVI 2695

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQ--DFEVKEKDVAIL--EVE 1039
                  D GV  C   ++  ++ + +  T+   P  +   +  D  V   + A L  E++
Sbjct: 2696 PGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEID 2755

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            I+   A +VW++DG  ++   N     + G I  L I    V++EG Y+CI  + +  A 
Sbjct: 2756 ISIPMASIVWQKDGISLREDSN-IRISRDGQI--LEINQVQVNNEGRYTCIATNNAGNAT 2812

Query: 1100 V---TVVELPPEII----TRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNH 1151
                  V +PP              +N+ +        +      +RW+KDG  +   N 
Sbjct: 2813 KFFGLTVHVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTH-NE 2871

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE-EPSINFTLRLPEFI 1206
              + +    + L+I   +   AG+++C     VGN   + +L V   P I      P  +
Sbjct: 2872 PGVAVSNSGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGA-EFPHNV 2930

Query: 1207 LVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             V  N    L   TV IP    ++ WYK    +   +   LIS     TL I      D+
Sbjct: 2931 SVVNNMGIELRCPTVAIP--VPEIVWYKDGHRLHPFQSGVLISP-DGTTLRIPNAQLHDE 2987

Query: 1264 CEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEW 1321
              Y CV  + A    KL    ++ PP IV  E  +  +  G   T+  +    P+P   W
Sbjct: 2988 GVYQCVATNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTW 3047

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              N+  I      +  ID  +  L I  V   D G+++  + N+ G+    +++ +  +P
Sbjct: 3048 TKNNAFISPAS-IRYDIDP-AGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQP 3105

Query: 1382 S-PPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTS 1439
            +  PG+  +      S+ +  D    TG  T  I +  + Q +   E   +  I+     
Sbjct: 3106 TITPGRGRVTTQIGQSVRLFCDA---TGVPTPEILWQKDGQRVSPMEGFLI--ISDGMLQ 3160

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I + + + + R+   A N           + +KVI E   + P + +  K      +  +
Sbjct: 3161 INDAQPSDAGRYDCIAKNGAG-------ADVFKVILEVH-EPPQIAETTKTYEIRVDASV 3212

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
            EL C  GG+P+P + W  +G++L        N                Y C+A ND G  
Sbjct: 3213 ELECRVGGIPKPNIRWLFNGRELGAQSLKLAN-GNLKIPVVRAEDSGAYTCLAQNDAGFA 3271

Query: 1560 ETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
            +   ++ +   P +     E  +    V    ++T   +G PPPEV W K+G  +E    
Sbjct: 3272 QAERILVVLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAGR 3331

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
              +T   +  + R++E   S S  YT  A+N+ G++ +   L V   P+
Sbjct: 3332 ITMTENHELIIDRVQE---SDSGTYTCVATNSIGSNRLNFYLTVQVAPT 3377



 Score =  186 bits (452), Expect = 8e-45
 Identities = 233/1073 (21%), Positives = 412/1073 (38%), Gaps = 96/1073 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            IPP  S + +   +     + L C+    P P I+W  K    +P    + +I S+    
Sbjct: 2541 IPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWR-KDNLPIPLSTRAFSISSNG--- 2596

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR---- 747
               L I + ++   G Y+ +A N  GE SL I+LK++    EPP ++  L+   ++    
Sbjct: 2597 -GSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQ----EPPIILGELEVNRMQHVQL 2651

Query: 748  -QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTL 805
             +G+ + L     G P+P + W ++N+ +     K   D    T++ P  +  D GVYT 
Sbjct: 2652 VEGDDIELPCPTTGYPKPRVAWFRDNRILSPPEYKIKDDG---TLVIPGAMPFDAGVYTC 2708

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGTIKLVARVTRN-PVP 862
             A N  G +  S  +TV         PPL ++ ++  +I V      +L   +  + P+ 
Sbjct: 2709 SAVNEAGNSSISINVTV-------MVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMA 2761

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            SI W ++   +     I  + DG+ +E+    V++E   G Y C+A+N+AG ++    +T
Sbjct: 2762 SIVWQKDGISLREDSNIRISRDGQILEINQVQVNNE---GRYTCIATNNAGNATKFFGLT 2818

Query: 923  IDVEKV----TFVKHLQKSYETEEGKTVILECQTSHTVSTKWY-------HNKKEISGMD 971
            + V  +      V  +  S   ++   +          + +WY       HN+  ++  +
Sbjct: 2819 VHVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSN 2878

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
              E+++  R               ++  I K    +  +  +    EF   +    V   
Sbjct: 2879 SGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVS--VVNNM 2936

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
             + +    +     ++VW +DG  + P ++       G    L I N  +HDEG Y C+ 
Sbjct: 2937 GIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPDG--TTLRIPNAQLHDEGVYQCVA 2994

Query: 1092 RD---ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIE-LTKGDALVRWFKDGSEI 1146
             +   E        +++PP I++R  NQ  V  G   T + E        V W K+ + I
Sbjct: 2995 TNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFI 3054

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF 1205
              ++ I+  ID     L I    + D G + C V NS       ++ +  +  T+     
Sbjct: 3055 SPAS-IRYDID-PAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRG 3112

Query: 1206 -ILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             +         L  +     T ++ W K    +   E F +ISD     L I      D 
Sbjct: 3113 RVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISD---GMLQINDAQPSDA 3169

Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
              Y C+  +       KV + V  PP+I +  + Y I+  + V L       P+PN  W+
Sbjct: 3170 GRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWL 3229

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             N + +        S+   + +L I  V   D+G Y    +N+ G A  E  + +LD P 
Sbjct: 3230 FNGRELGA-----QSLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLDVPR 3284

Query: 1383 PPGKPN-----ILEIDSSSINIC----WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
             P  P       + ++  ++  C    +  PE T     I  V     I  TE       
Sbjct: 3285 LPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGIL-VEPAGRITMTE------- 3336

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
               +  I  ++ + S  +   A N +     S    +Y  ++     +PT      ++  
Sbjct: 3337 -NHELIIDRVQESDSGTYTCVATNSI----GSNRLNFYLTVQV----APTFTHFPNDVEL 3387

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
                 +EL C   GVP P + W  +G ++     T++ R               Y C A 
Sbjct: 3388 AAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSVLAIGNVQKSDSGTYMCRAE 3447

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N  G       V ++  P I     D      +G+  ++   + G P PEV W KN   +
Sbjct: 3448 NILGVRTAITAVRVRVPPRIHRIPSDTTL--TLGERAVLNCAVNGDPKPEVTWLKNNRPV 3505

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                  +   +     + I     S +  Y  +A N  G   V   L++  +P
Sbjct: 3506 ALT---DTMQQSSDGSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRP 3555



 Score =  185 bits (451), Expect = 1e-44
 Identities = 238/1090 (21%), Positives = 426/1090 (39%), Gaps = 80/1090 (7%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP  S  P       G ++ L C  + +P P   W   G ++  D++    ++      
Sbjct: 1798 VPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDEGS--- 1854

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQ 748
               L I++V++   G Y  + VN+ G  +  I L +K   +   E P+V+E + +  VR 
Sbjct: 1855 ---LIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVR- 1910

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLK 806
                 +  Q  G PRP ++W K+ +P++ L   T    +T  I+ L+P    D G Y  +
Sbjct: 1911 -----IPCQATGTPRPQVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPY---DNGRYECR 1962

Query: 807  AENSEGIAETSAVITVE-EPT---EENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPV 861
            A++  G       I  +  P    E   + P+ +  F E    E  T+ L   VT  +P 
Sbjct: 1963 AQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVV--FTE----EDQTVILECNVTDSHPP 2016

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
              +TWY+N + I     I  +F+  +  L +  +  E D+G Y C A+N  G S     +
Sbjct: 2017 AEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPE-DAGHYHCEATNGQGSSQRHFSL 2075

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979
             + V  V      Q+    + G ++ + C+ S     +  W      IS  + R  I   
Sbjct: 2076 EVHVGPV-IRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAISSQNSRYHIASN 2134

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAIL 1036
                         D GV  CI K+   +   VV   +   P       D         IL
Sbjct: 2135 --GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTSDIVRTLSSSVIL 2192

Query: 1037 EVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
              E       ++ W ++G  +       +    G +R   IR+    D G Y C+  +++
Sbjct: 2193 PCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSLR---IRSVEEEDSGVYRCVAVNQA 2249

Query: 1096 --CTAEVTV-VELPPEI-ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS- 1149
                  +T+ +  PP +     +N       K      ++       RW K+  E+  + 
Sbjct: 2250 GHDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNY 2309

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPE 1204
              ++L  DG    L I D +  D G Y+CE  N     S+   +     P I  +    E
Sbjct: 2310 GKMELLEDG---SLMIRDVESIDRGSYTCEATNAVGVLSRDIRLEVSVAPKITGSKTPVE 2366

Query: 1205 FILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
            + +   ++      +T   P     + WYK    +   E+   I D +  TL I      
Sbjct: 2367 YPVGQYDSIELQCMVTDAFPPPI--IKWYKGDETLTGQEEAVTIKD-QGITLEIGSVNIA 2423

Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPND 1319
            +  EY C   +      +   + V+  P I++ + EY    +  D+TLL + +  P P  
Sbjct: 2424 NAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTI 2483

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             W  ++K ++        +  +  SL I   ++TD+G Y     NN G+A    ++ +  
Sbjct: 2484 TWERDNKPLE--LRDSHYLIGEDGSLRITAPQHTDSGGYVCVASNNIGYAIKNFHLVVKI 2541

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
             P    +  ++ I          +       TI +         +T   S+ +   + T 
Sbjct: 2542 PPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRAFSISSNGGSLT- 2600

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNED 1498
            I + +   S  +   A NEV      ++ +    ++E  I    +E   ++++     +D
Sbjct: 2601 INSTREGDSGIYSCIASNEV----GEQSLDILLKVQEPPIILGELEVNRMQHVQLVEGDD 2656

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            IEL C   G P+P+V W+RD + L   +   ++                Y C A N+ G 
Sbjct: 2657 IELPCPTTGYPKPRVAWFRDNRILSPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAGN 2716

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDK 1617
               S  V +   P++  +   +     + +   +   I+  IP   ++W K+G  L  D 
Sbjct: 2717 SSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGISLREDS 2776

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG-PV--I 1674
              NI       ++ I +++ ++  +YT  A+N AG ++    L V+  P  P+G PV  +
Sbjct: 2777 --NIRISRDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPM 2834

Query: 1675 MREISRESVT 1684
            M  I+ +  T
Sbjct: 2835 MMSINEDDST 2844



 Score =  178 bits (434), Expect = 1e-42
 Identities = 236/1086 (21%), Positives = 424/1086 (39%), Gaps = 96/1086 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+ S    +  V     + L C     P P I W+  G+ I            ++ ++ 
Sbjct: 1073 PPSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIKNGQTI-----------PNLGLHQ 1121

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIVRQGE 750
            S L ++ V +   GTY     N  G + + I L I      PP  + +E    + V QG+
Sbjct: 1122 SALTLSYVTEQDAGTYICRVSNLAGFSEIEITLFILV----PPAHEGVETTGVVNVTQGD 1177

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            SV L   V G P P I+W K+N P+         +T    +++   V +EG Y   A N 
Sbjct: 1178 SVTLPCNVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQMSVAEEGQYRCVASNI 1237

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G       IT+         PP       E  V   G+I L       P+P + W ++ 
Sbjct: 1238 AGNVSKDVRITI-------LVPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDG 1290

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +S +    +  D  ++++ +T   SE  +G Y C+ +N AG ++    +T+ V     
Sbjct: 1291 AQLSIATRNVRILDLGSLQIDVT---SEEHTGTYTCLVTNEAGSTNR--LITLSVIVPPR 1345

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXX 989
            +   Q  Y   +G+ +IL C  + T       +K+ I+  ++      +           
Sbjct: 1346 IFDGQTQYTVVQGQAIILHCPATGTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGV 1405

Query: 990  XXXDVGVIKCIVKDQETS-----TMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
               D G  KC+V++   S     T+ V V   I E +   + F +       L  E+   
Sbjct: 1406 LPTDFGTYKCVVRNDGGSVYKDITLSVHVAPVIEEAVE--ETFSITIGQTVSLPCEVTGT 1463

Query: 1044 TADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT- 1101
               +V W + G  I    +    +       L I +T   D G Y C+    +    VT 
Sbjct: 1464 PPPIVTWYKSGNPISVTSSMVITQD-----SLDIYSTRPFDTGIYQCVA--SNVAGNVTR 1516

Query: 1102 ----VVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL----VRWFKDGSEIQFSNHI 1152
                +V +PP I    Q+    +  +    IEL  + D +    + W+KDG  +   N  
Sbjct: 1517 NFRLIVMIPPSI----QDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDP 1572

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPE-FILVP 1209
            +L        L+I + D +D+GEY+C V N   K +  +T+        L  P+ +  + 
Sbjct: 1573 RLR-KTAFGTLQIVNVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSPDSYTSLI 1631

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
             N      +       DVTW K  + +   +    I+     +L+I     +D   YTC 
Sbjct: 1632 RNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYIT--PSNSLLIASTMREDSGIYTCN 1689

Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            + +        +E+ V  PP  ++  +  Y +   + V+L  + Q++P P   W+ + ++
Sbjct: 1690 VSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKDGRV 1749

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGK 1386
            I    +T      + +SL I      D+G+Y     N  G+      + +   P   PG 
Sbjct: 1750 I---PYTNSHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINVQVPPYISPGP 1806

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
              I      ++ +  D        T+          D + +  +   +   + ++ L   
Sbjct: 1807 DTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDEGSLIISDVRELDAG 1866

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE-PNEDIELTCIF 1505
            + Y      VN+      ++T      +K+    +P +   L  +  +  N ++ + C  
Sbjct: 1867 AYY---CLVVNQA----GADTRRITLTVKD----APRIINELPEVMEQIMNTEVRIPCQA 1915

Query: 1506 GGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             G P+P+V+W++DG+ ++  +  T                   Y+C A ++ G       
Sbjct: 1916 TGTPRPQVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPYDNGRYECRAQSESGFDSIDVF 1975

Query: 1565 VGIQQKPVITISN--EDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLENDKEYN 1620
            +  Q +P I   N  +D        D+ ++    V +  PP EV WY+NG  +    +  
Sbjct: 1976 IDTQVRPHIAGENTPDDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIG 2035

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            I  +   + +R+  L+   +  Y  EA+N  G+S    +L+V+       GPVI R   +
Sbjct: 2036 IHFETGDTSLRLPYLRPEDAGHYHCEATNGQGSSQRHFSLEVH------VGPVI-RNRRQ 2088

Query: 1681 ESVTIE 1686
            E VT++
Sbjct: 2089 EQVTVQ 2094



 Score =  174 bits (423), Expect = 3e-41
 Identities = 238/1080 (22%), Positives = 422/1080 (39%), Gaps = 91/1080 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P   +++ +   V  G  I + C    +P+  I W+F G+  +  +N    I S+     
Sbjct: 2081 PVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMF-GDIAISSQNSRYHIASN----- 2134

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L +  V+    G +T +A N  G  +  + + +      PP + +    ++     SV
Sbjct: 2135 GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIV----PPSINDGTSDIVRTLSSSV 2190

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            IL  +  G P P ITW KN  P+       +        ++  + +D GVY   A N  G
Sbjct: 2191 ILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSLRIRSVEEEDSGVYRCVAVNQAG 2250

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-E 871
                  ++T+   T  + +P    +R     V EK  + +   ++ +P P   W +NN E
Sbjct: 2251 --HDYKMLTLWIHTPPSLQPDA--SRNVSTGVDEK--VIIPCNISGSPKPQYRWLKNNRE 2304

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTF 930
            ++     +    DG    L+I +V+S ID G Y C A+N+ G  S   R+ + V  K+T 
Sbjct: 2305 LLMNYGKMELLEDGS---LMIRDVES-IDRGSYTCEATNAVGVLSRDIRLEVSVAPKITG 2360

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVST---KWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             K     Y   +  ++ L+C  +        KWY   + ++G +    I++ +       
Sbjct: 2361 SK-TPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTGQEEAVTIKD-QGITLEIG 2418

Query: 988  XXXXXDVGVIKCIV-KDQETSTM--LVVKETIPEFIRKLQDF--EVKEKDVAILEVEINS 1042
                 + G   C    D   ++M   +  +  P  +    ++   V+  D+ +L     +
Sbjct: 2419 SVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGN 2478

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT- 1101
             T  + WERD + ++ + + Y   + G +R    ++T   D G Y C+  +    A    
Sbjct: 2479 PTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQHT---DSGGYVCVASNNIGYAIKNF 2535

Query: 1102 --VVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDG 1158
              VV++PP+  T+ +   +      T   +     A  + W KD   I  S     +I  
Sbjct: 2536 HLVVKIPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRA-FSISS 2594

Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI---NFTLRLPEFILVPAN 1211
                L I      D+G YSC    EVG      +L V+EP I      +   + + +   
Sbjct: 2595 NGGSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPIILGELEVNRMQHVQLVEG 2654

Query: 1212 TDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             D    +E+P  T       V W++   ++   E + +  D    TL+I      D   Y
Sbjct: 2655 DD----IELPCPTTGYPKPRVAWFRDNRILSPPE-YKIKDD---GTLVIPGAMPFDAGVY 2706

Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQ-AFPQPNDEWI 1322
            TC  ++    + + + V V  PP +VD  R  +  +   +   L  +   + P  +  W 
Sbjct: 2707 TCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQ 2766

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             +   +++  + + S D +   L I +V+  + G Y     NN G+A     +T+   P 
Sbjct: 2767 KDGISLREDSNIRISRDGQI--LEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPI 2824

Query: 1383 -PPGKP------NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
             P G P      +I E DS+ +  C          TI +Y            ++V N   
Sbjct: 2825 FPDGNPVNPMMMSINEDDSTQLG-C--HASGYPPPTIRWYKDGRLVTHNEPGVAVSN--- 2878

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
               S + L+ N   R  A     V  S     ++ Y +    + +    E P  N++   
Sbjct: 2879 ---SGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFP-HNVSVVN 2934

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
            N  IEL C    +P P++ WY+DG +L   ++      +                Y+C+A
Sbjct: 2935 NMGIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVA 2994

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             N  GE      + I   PVI +S E  +     G    +     G+P P V W KN   
Sbjct: 2995 TNVAGEEMKLFNLQIDVPPVI-VSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAF 3053

Query: 1613 LENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
            +      Y+I   +   ++ I  +  +    +    SN+AG  +  + L+V  +P+   G
Sbjct: 3054 ISPASIRYDI---DPAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPG 3110



 Score =  161 bits (390), Expect = 3e-37
 Identities = 240/1096 (21%), Positives = 420/1096 (38%), Gaps = 102/1096 (9%)

Query: 633  PPTFSKKPKAQYVDEGSD--ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            PP+  +   ++ V  G D  +++ C +   P+P   WL    E++ +      +E     
Sbjct: 2263 PPSL-QPDASRNVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNYGKMELLEDGS-- 2319

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L I +V+    G+YT  A N  G  S  I L++    K       P++   V Q +
Sbjct: 2320 ----LMIRDVESIDRGSYTCEATNAVGVLSRDIRLEVSVAPKITGSKT-PVEYP-VGQYD 2373

Query: 751  SVILSAQVVGN-PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            S+ L   V    P P I W K ++ +    +A+  K  G T  I  +    + + G Y  
Sbjct: 2374 SIELQCMVTDAFPPPIIKWYKGDETLTGQEEAVTIKDQGITLEIGSVN---IANAGEYYC 2430

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A N  G+A  +  I V+        P +   + + +T  +   I L+     NP P+IT
Sbjct: 2431 TATNDAGMASMNWTIDVQ------VTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTIT 2484

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W R+N+ +   ++      GE+  L IT      DSG Y CVASN+ G +     + + +
Sbjct: 2485 WERDNKPLELRDS--HYLIGEDGSLRIT-APQHTDSGGYVCVASNNIGYAIKNFHLVVKI 2541

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXX 983
               T  +  Q+       ++V L CQ +     +  W  +   I  +  R          
Sbjct: 2542 PPKTSTQ--QEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIP-LSTRAFSISSNGGS 2598

Query: 984  XXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILE--- 1037
                     D G+  CI  ++  E S  +++K   P  I  L + EV   + V ++E   
Sbjct: 2599 LTINSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPII--LGELEVNRMQHVQLVEGDD 2656

Query: 1038 VEINSETAD-----VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
            +E+   T       V W RD  I+ P +  Y  +  G    L I      D G Y+C   
Sbjct: 2657 IELPCPTTGYPKPRVAWFRDNRILSPPE--YKIKDDG---TLVIPGAMPFDAGVYTCSAV 2711

Query: 1093 DESCTAEVTV---VELPPEIITRLQNQKV----NKGNKATFEIELTKGDALVRWFKDGSE 1145
            +E+  + +++   V +PP ++   +   +    N   +   EI+++   A + W KDG  
Sbjct: 2712 NEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGIS 2771

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLR 1201
            ++  ++I+++ DG  Q L+I    +++ G Y+C   N+   A     LTV  P I     
Sbjct: 2772 LREDSNIRISRDG--QILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGN 2829

Query: 1202 LPEFILVPANTDAYLTVEI-----PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256
                +++  N D    +       P  T  + WYK   ++   E    +S+     L I 
Sbjct: 2830 PVNPMMMSINEDDSTQLGCHASGYPPPT--IRWYKDGRLVTHNEPGVAVSN-SGEVLRIN 2886

Query: 1257 KCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQA 1313
            +       ++TCV      + +K  V  V   P+I   ++     +     + L     A
Sbjct: 2887 RVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVSVVNNMGIELRCPTVA 2946

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P P   W  +   +   + +   I     +L I   +  D G+Y+    N  G      
Sbjct: 2947 IPVPEIVWYKDGHRLHPFQ-SGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLF 3005

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
            N+ I D P     P I+  + + I +        G ST I          T  W      
Sbjct: 3006 NLQI-DVP-----PVIVSREPNQIAVI------AGGSTTIDCESYGVPKPTVTWTKNNAF 3053

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKN 1490
                +   ++            V +  + +   +     V +   +Q    PT+      
Sbjct: 3054 ISPASIRYDIDPAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRGR 3113

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYK 1549
            +TT+  + + L C   GVP P++ W +DG+++   +     +                Y 
Sbjct: 3114 VTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDGMLQINDAQPSDAGRYD 3173

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            CIA N  G      ++ + + P I  + +  + +     E  +   + GIP P + W  N
Sbjct: 3174 CIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDASVE--LECRVGGIPKPNIRWLFN 3231

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            G +L        + K     ++I  ++   S  YT  A N AG +  E  L V D P  P
Sbjct: 3232 GRELGAQ-----SLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLDVPRLP 3286

Query: 1670 EGPVIMREISRESVTI 1685
              P   RE S  ++++
Sbjct: 3287 RPP---REQSEMTISV 3299



 Score =  159 bits (385), Expect = 1e-36
 Identities = 228/1071 (21%), Positives = 415/1071 (38%), Gaps = 91/1071 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+         V  G  I+L C    IP P++ W   G +      +S+A  +   + 
Sbjct: 1251 VPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQ------LSIATRNVRILD 1304

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L+I    +   GTYT +  N  G  +  I L +      PP++ +      V QG++
Sbjct: 1305 LGSLQIDVTSEEHTGTYTCLVTNEAGSTNRLITLSVIV----PPRIFDGQTQYTVVQGQA 1360

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810
            +IL     G P PTITW K    +       D D  + T+ +      D G Y     N 
Sbjct: 1361 IILHCPATGTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGVLPTDFGTYKCVVRND 1420

Query: 811  EGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
             G       ++V   P  E A    F      IT+ +  T+ L   VT  P P +TWY++
Sbjct: 1421 GGSVYKDITLSVHVAPVIEEAVEETF-----SITIGQ--TVSLPCEVTGTPPPIVTWYKS 1473

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
               IS + ++    D  ++++  T      D+G Y+CVASN AG  +   R+ + +    
Sbjct: 1474 GNPISVTSSMVITQD--SLDIYSTR---PFDTGIYQCVASNVAGNVTRNFRLIVMIP--P 1526

Query: 930  FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             ++    +  TE G  + LEC+          WY + + + G  +   +++         
Sbjct: 1527 SIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPL-GTYNDPRLRKTAFGTLQIV 1585

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILE-VEINSE 1043
                 D G   C V +        V  T+   P  +     +    ++   L+ +     
Sbjct: 1586 NVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFP 1645

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAE 1099
              DV W ++G  +  +  +Y          L I +T   D G Y+C + +    +    E
Sbjct: 1646 PPDVTWLKNGAPLNQEDVRYYITPS---NSLLIASTMREDSGIYTCNVSNTAGHQYKHME 1702

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSN-HIQLTID 1157
            +TV   P  I +   +  V   N  +   E+ +     + W KDG  I ++N H ++   
Sbjct: 1703 LTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKDGRVIPYTNSHYRI--- 1759

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL 1216
             +   L I    + D+G Y+C   N     I+     +    +++P +I   P    AYL
Sbjct: 1760 -QPSSLDIPMAVVRDSGVYTCIATN-----IVGNISRNYQINVQVPPYISPGPDTITAYL 1813

Query: 1217 --TVEIPDETLDV-----TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
               V +P +++ V      W K    +  D  +F  + +    +LII    E D   Y C
Sbjct: 1814 GQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDE---GSLIISDVRELDAGAYYC 1870

Query: 1269 VLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            ++++ A + T+     V+  P+I++   E   +   ++V +       P+P   W  + +
Sbjct: 1871 LVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVRIPCQATGTPRPQVSWFKDGR 1930

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP----- 1381
             I++ +      D+   +L I  ++  D G Y+ R ++  G   +++ +    +P     
Sbjct: 1931 PIEQLRGYTVLGDN---TLLISSLQPYDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGE 1987

Query: 1382 SPPGKPNIL--EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQT 1438
            + P  P ++  E D + I  C +  ++   + + +Y    Q I     I +   T  T  
Sbjct: 1988 NTPDDPVVVFTEEDQTVILEC-NVTDSHPPAEVTWY-QNGQAILARADIGIHFETGDTSL 2045

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             +  L+   +  +   A N         +  ++ +  E  +      +  + +T +    
Sbjct: 2046 RLPYLRPEDAGHYHCEATN-----GQGSSQRHFSL--EVHVGPVIRNRRQEQVTVQVGHS 2098

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            I + C   GVP  ++ W      + +  + Y   +                + CIA N  
Sbjct: 2099 ITIHCEASGVPDARILWMFGDIAISSQNSRYHIASNGSLHLREVQVIDSGVFTCIAKNSA 2158

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G       + +   P I     DI +   +    ++     G+P PE+ WYKNG  L N 
Sbjct: 2159 GNDTRVVNINVIVPPSINDGTSDIVR--TLSSSVILPCESAGVPFPEITWYKNGAPL-NL 2215

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
               N+  K  +  +RI+ ++   S  Y   A N AG     +TL ++  PS
Sbjct: 2216 SNPNL-EKLFSGSLRIRSVEEEDSGVYRCVAVNQAGHDYKMLTLWIHTPPS 2265



 Score =  159 bits (385), Expect = 1e-36
 Identities = 266/1181 (22%), Positives = 448/1181 (37%), Gaps = 123/1181 (10%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA-TLVIREVFPEDAGTFT 582
            G  +   C   G P P ITW ++   I P  D   +YD D +A TL +  V P D GT+ 
Sbjct: 1358 GQAIILHCPATGTPPPTITWSKEGIAI-PLND--PHYDVDEIAGTLTMFGVLPTDFGTYK 1414

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            CV +N  G       +  +  LS H + +                I E +  TFS     
Sbjct: 1415 CVVRNDGG------SVYKDITLSVHVAPV----------------IEEAVEETFS----- 1447

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
              +  G  + L C +   P P + W   G  I        ++ S M +    L I + + 
Sbjct: 1448 --ITIGQTVSLPCEVTGTPPPIVTWYKSGNPI--------SVTSSMVITQDSLDIYSTRP 1497

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
            F  G Y  VA N  G  +    L +      PP + +   +     G  + L  +  G P
Sbjct: 1498 FDTGIYQCVASNVAGNVTRNFRLIVMI----PPSIQDGPATRTTEVGAHIELECRADGIP 1553

Query: 763  RPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
             P ITW K+ +P+     P        ++ I+   + +D G Y     N  G A     +
Sbjct: 1554 LPDITWYKDGEPLGTYNDPRLRKTAFGTLQIVNVDQ-EDSGEYACYVSNDAGKASKFVTL 1612

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            TV          P+ ++     T   +  + L       P P +TW +N   ++  E + 
Sbjct: 1613 TVN-------LAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLN-QEDVR 1664

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
                  N  L+I +   E DSG Y C  SN+AG       +T+ +   T +     SY+ 
Sbjct: 1665 YYITPSN-SLLIASTMRE-DSGIYTCNVSNTAGHQYKHMELTVYLPP-TSINSGDTSYDV 1721

Query: 941  EEGKTVILECQT-SHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
                 V L C+  S+   T  W  + + I   +    IQ               D GV  
Sbjct: 1722 TLNNPVSLPCEVQSYPPPTITWLKDGRVIPYTNSHYRIQP---SSLDIPMAVVRDSGVYT 1778

Query: 999  CIVKD--QETSTMLVVKETIPEFIRKLQD--FEVKEKDVAILEVEINSETADVVWERDGE 1054
            CI  +     S    +   +P +I    D       ++V +    I   T   +W++ G 
Sbjct: 1779 CIATNIVGNISRNYQINVQVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGL 1838

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIIT 1111
             +    +++     G    L I +    D G Y C++ ++  + T  +T+ V+  P II 
Sbjct: 1839 QLNYDDSRFHKLDEG---SLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIIN 1895

Query: 1112 RL---QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
             L     Q +N   +   +   T     V WFKDG  I+      +  D     L I   
Sbjct: 1896 ELPEVMEQIMNTEVRIPCQATGTPRPQ-VSWFKDGRPIEQLRGYTVLGD---NTLLISSL 1951

Query: 1169 DLDDAGEYSC----EVG-NSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIP 1221
               D G Y C    E G +S    I T   P I    T   P  +    +    L   + 
Sbjct: 1952 QPYDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQTVILECNVT 2011

Query: 1222 DE--TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            D     +VTWY+    I       +  +    +L +     +D   Y C   + + +++ 
Sbjct: 2012 DSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEATNGQGSSQR 2071

Query: 1280 KVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
               + V   P I +  +E   ++ G  +T+  +    P     W+     I   ++++  
Sbjct: 2072 HFSLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAISS-QNSRYH 2130

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSS 1396
            I S + SL +++V+  D+G++    +N+ G+    +N+ ++  PS   G  +I+   SSS
Sbjct: 2131 IAS-NGSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTSDIVRTLSSS 2189

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            + +     E+ G        V + EI    W   KN      S  NL+   S   R  +V
Sbjct: 2190 VIL---PCESAG--------VPFPEI---TW--YKNGAPLNLSNPNLEKLFSGSLRIRSV 2233

Query: 1457 NEVDIS-----DASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVP 1509
             E D         ++    YK++    I +P   +P   +N++T  +E + + C   G P
Sbjct: 2234 EEEDSGVYRCVAVNQAGHDYKML-TLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISGSP 2292

Query: 1510 QPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
            +P+  W ++ ++L     K                     Y C A N  G +     + +
Sbjct: 2293 KPQYRWLKNNRELLMNYGKMELLEDGSLMIRDVESIDRGSYTCEATNAVGVLSRDIRLEV 2352

Query: 1568 QQKPVITISNEDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
               P IT S   ++      D   L   V +  PPP + WYK G++    +E  +T K++
Sbjct: 2353 SVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYK-GDETLTGQEEAVTIKDQ 2411

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
               + I  +  +++ +Y   A+N AG +S+  T+ V   PS
Sbjct: 2412 GITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPS 2452



 Score =  155 bits (376), Expect = 1e-35
 Identities = 232/1069 (21%), Positives = 399/1069 (37%), Gaps = 93/1069 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P TF  +    Y   G D +L C + ++    + W+ +G  +  D  I  +         
Sbjct: 528  PTTFMPRRTPGYY--GMDAVLTCDVESMIPFTVRWMRRGTPL--DGPIEFSETGS----- 578

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +   I N     EG Y+ +A N EG A     L I     EPP VI    +  V  G   
Sbjct: 579  ATWTIKNSDSRIEGVYSCIAENEEGSARSETYLDIT----EPPPVIARPYNTSVLPGSDG 634

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            ++S  +       ITW K N  V      +     +   +++     D G Y  +A N  
Sbjct: 635  VMSCFISSTVEYNITWDKPNTLVSLQGHNRVSLMNNGSLVIQDVHPGDAGSYRCRAWNEG 694

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            G+ E    + V+E  +        IN +Q  +T      I L       P P + W ++ 
Sbjct: 695  GVTEEHVYLYVQERPQ--------INAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDG 746

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            + + P    T+   GE I  +  N   E D G Y C+ASN+AG  S    V +   +   
Sbjct: 747  QEL-PIVPGTRR--GEIIHQIF-NASRE-DQGIYTCLASNTAG--SDLLNVYVSYHEPPR 799

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            ++  Q  Y T   +   L C TS     +  W+   ++++ + +  I   G         
Sbjct: 800  IQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNG---DLDIMG 856

Query: 989  XXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSET 1044
                D G   C   ++    + T+ +   + P  ++   D  V    +V++  + +    
Sbjct: 857  VQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPP 916

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100
              V W + G+       +    + G+   L+IR+  V D G Y C+  +E      +A++
Sbjct: 917  PAVTWRKVGQSHLDINPRITMTEDGN---LFIRDMQVEDSGTYVCVAHNEHGSTEASAQL 973

Query: 1101 TVVEL-PPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEI--QFSNHIQLT 1155
             +  L  P+I    Q + V   +       +  G+    V WF     +  ++S  ++L 
Sbjct: 974  RITNLIQPQISATSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELF 1033

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
             DG    L I    + DAG Y+C     +GN +K T I     PSI+ T     + ++  
Sbjct: 1034 PDG---SLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGT--ETSYTVIHH 1088

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
             +   L          + W K    I +         + +  L +   TE D   Y C +
Sbjct: 1089 ESVTLLCPAAGHPPPLIEWIKNGQTIPNL-------GLHQSALTLSYVTEQDAGTYICRV 1141

Query: 1271 LDAKSTTKLKVEV-VEFPP--KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
             +    +++++ + +  PP  + V+      + +G  VTL  + +  P P   W  ++  
Sbjct: 1142 SNLAGFSEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLP 1201

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGK 1386
            + +    +    +    L I+++   + G Y+    N  G+   ++ +TIL  PS  PG 
Sbjct: 1202 LPEA--GRNFYVNTDGGLVIQQMSVAEEGQYRCVASNIAGNVSKDVRITILVPPSIEPGN 1259

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
                 +   SI I   E        +++     Q    T  + + ++   Q  + + +  
Sbjct: 1260 TEYAVVAGGSI-ILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILDLGSLQIDVTSEEHT 1318

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
             +Y       NE     A  T    ++I  + I  P +       T    + I L C   
Sbjct: 1319 GTY--TCLVTNE-----AGSTN---RLITLSVIVPPRIFDGQTQYTVVQGQAIILHCPAT 1368

Query: 1507 GVPQPKVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
            G P P +TW ++G  +      Y   E                 YKC+  ND G V    
Sbjct: 1369 GTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGVLPTDFGTYKCVVRNDGGSVYKDI 1428

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             + +   PVI  + E+      +G    +   + G PPP V WYK+GN +       IT 
Sbjct: 1429 TLSVHVAPVIEEAVEE-TFSITIGQTVSLPCEVTGTPPPIVTWYKSGNPISVTSSMVITQ 1487

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                  + I   +   +  Y   ASN AG  +    L V   PS  +GP
Sbjct: 1488 DS----LDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIPPSIQDGP 1532



 Score =  153 bits (371), Expect = 5e-35
 Identities = 243/1163 (20%), Positives = 426/1163 (36%), Gaps = 106/1163 (9%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            +V   CQ  G+P P I+W +    I  S   + +    N  +L I      D+G ++C+A
Sbjct: 2559 SVTLRCQAAGFPAPTISWRKDNLPIPLST--RAFSISSNGGSLTINSTREGDSGIYSCIA 2616

Query: 586  KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
             N  G  S    L V+ P    G E+ V                       ++    Q V
Sbjct: 2617 SNEVGEQSLDILLKVQEPPIILG-ELEV-----------------------NRMQHVQLV 2652

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            + G DI L C     P+P +AW      + P E     I+ D       L I     F  
Sbjct: 2653 E-GDDIELPCPTTGYPKPRVAWFRDNRILSPPE---YKIKDD-----GTLVIPGAMPFDA 2703

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILSAQVVGNP 762
            G YT  AVN  G +S+ I + +      PP +++   P+  +++    + +     +  P
Sbjct: 2704 GVYTCSAVNEAGNSSISINVTVMV----PPLLVDAYRPVDIIVILNNPARLYCEIDISIP 2759

Query: 763  RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
              +I W K+   ++            I  +   +V +EG YT  A N+ G A     +TV
Sbjct: 2760 MASIVWQKDGISLREDSNIRISRDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTV 2819

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQ 881
              P       P  +N    +++ E  + +L    +  P P+I WY++  +++ +E  +  
Sbjct: 2820 HVPPIFPDGNP--VNPMM-MSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAV 2876

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
            +  GE + +   N  + I +G + CVAS+  G  S    + + V           +    
Sbjct: 2877 SNSGEVLRI---NRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVSVV 2933

Query: 942  EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
                + L C T         WY +   +       +I                D GV +C
Sbjct: 2934 NNMGIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPD-GTTLRIPNAQLHDEGVYQC 2992

Query: 1000 IVKD--QETSTMLVVKETIPEFI--RKLQDFEVKEKDVAILEVE-INSETADVVWERDGE 1054
            +  +   E   +  ++  +P  I  R+     V       ++ E        V W ++  
Sbjct: 2993 VATNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNA 3052

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIIT 1111
             I P   +YD +  G    L+I   +V DEG + C + +   + T  + + V++ P I  
Sbjct: 3053 FISPASIRYDIDPAG---LLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITP 3109

Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
                     G       + T      + W KDG  +       +  DG    L+I D   
Sbjct: 3110 GRGRVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDG---MLQINDAQP 3166

Query: 1171 DDAGEYSCEVGNSKCTAILTV-----EEPSINFTLRLPEFILVPANTDAYLTV-EIPDET 1224
             DAG Y C   N     +  V     E P I  T +  E I V A+ +    V  IP   
Sbjct: 3167 SDAGRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYE-IRVDASVELECRVGGIPKP- 3224

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEV 1283
             ++ W     +    E       +    L I     +D   YTC+   DA      ++ V
Sbjct: 3225 -NIRW-----LFNGRELGAQSLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILV 3278

Query: 1284 V-EFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V + P  P+    + E  I       L      +P P   W  +  +++          +
Sbjct: 3279 VLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAGRITM---T 3335

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
            ++  L I +V+ +D+G Y     N+ G   +   +T+   P+    PN +E+ + +    
Sbjct: 3336 ENHELIIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVELAAGNRLEL 3395

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
              E        I + V   + I        +++     +I N++ + S  +   A N + 
Sbjct: 3396 ICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSV----LAIGNVQKSDSGTYMCRAENILG 3451

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            +  A  T    +V        P + +   + T    E   L C   G P+P+VTW ++ +
Sbjct: 3452 VRTAI-TAVRVRV-------PPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKNNR 3503

Query: 1521 KLKTAKATYENRXXXXXXX-XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
             +       ++                 YKC A N +G  E S  + IQ +P+  +  ++
Sbjct: 3504 PVALTDTMQQSSDGSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRPMFVVEPQN 3563

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                H  G+  L+  + +G P P + W K G ++       I      + ++I   + + 
Sbjct: 3564 TTVSH--GENVLLDCIAQGEPEPSMRWQKEGFRVLPVGRVAIL---PNNTLKIVAAQLTD 3618

Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662
            S  Y   A N  G + + + L V
Sbjct: 3619 SGAYMCLAENQMGRAVMTIHLTV 3641



 Score =  150 bits (364), Expect = 4e-34
 Identities = 230/1120 (20%), Positives = 423/1120 (37%), Gaps = 100/1120 (8%)

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGS 649
            + + +  L++ + + +     T              ++   +PPT        Y V   +
Sbjct: 1666 YITPSNSLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNN 1725

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
             + L C + + P P I WL  G  ++P  N    I+       S L I        G YT
Sbjct: 1726 PVSLPCEVQSYPPPTITWLKDGR-VIPYTNSHYRIQP------SSLDIPMAVVRDSGVYT 1778

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
             +A N  G  S    + ++     PP +     ++    G++V L    +G P P   W 
Sbjct: 1779 CIATNIVGNISRNYQINVQV----PPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWD 1834

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            K+   +    ++         I+   +  D G Y     N  G       +TV++     
Sbjct: 1835 KSGLQLNYDDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDA---- 1890

Query: 830  AEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
               P  IN   E+  +   T +++  + T  P P ++W+++   I      T    G+N 
Sbjct: 1891 ---PRIINELPEVMEQIMNTEVRIPCQATGTPRPQVSWFKDGRPIEQLRGYTVL--GDNT 1945

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS---YETEEGKT 945
             L+I+++    D+G Y+C A + +G  S    +   V      ++         TEE +T
Sbjct: 1946 -LLISSLQP-YDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQT 2003

Query: 946  VILECQT--SH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            VILEC    SH      WY N + I       I  E              D G   C   
Sbjct: 2004 VILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEAT 2063

Query: 1003 DQETSTM--LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWERDGEIIK 1057
            + + S+     ++  +   IR  +  +V  +    + +   +     A ++W      I 
Sbjct: 2064 NGQGSSQRHFSLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAIS 2123

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQ 1114
             + ++Y     G    L++R   V D G ++CI ++   + T  V + V +PP I     
Sbjct: 2124 SQNSRYHIASNG---SLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTS 2180

Query: 1115 NQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLD 1171
            +      +      E + G     + W+K+G+ +  SN +++    G    L+I   + +
Sbjct: 2181 DIVRTLSSSVILPCE-SAGVPFPEITWYKNGAPLNLSNPNLEKLFSG---SLRIRSVEEE 2236

Query: 1172 DAGEYSC----EVGNSKCTAILTVEEP-------SINFTLRLPEFILVPANTDAYLTVEI 1220
            D+G Y C    + G+      L +  P       S N +  + E +++P N         
Sbjct: 2237 DSGVYRCVAVNQAGHDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISG------ 2290

Query: 1221 PDETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
                    W K  + ++ +  K  L+ D    +L+IR     D+  YTC   +A      
Sbjct: 2291 -SPKPQYRWLKNNRELLMNYGKMELLED---GSLMIRDVESIDRGSYTCEATNAVGVLSR 2346

Query: 1280 KVEV-VEFPPKIVDYER--EYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
             + + V   PKI   +   EY + +   + L  +   AFP P  +W    + +   +   
Sbjct: 2347 DIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTG-QEEA 2405

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNIL-EID 1393
             +I  +  +L I  V   +AG Y     N+ G A +   + +   PS   G+   L  + 
Sbjct: 2406 VTIKDQGITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQ 2465

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQ-EIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
            +  I +   E E     TI +       E+  + ++  ++ +   T+ Q+     S  + 
Sbjct: 2466 NIDITLLC-EAEGNPTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQH---TDSGGYV 2521

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A N +  +       ++ V+K      P      + +T    + + L C   G P P 
Sbjct: 2522 CVASNNIGYA----IKNFHLVVK----IPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPT 2573

Query: 1513 VTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            ++W +D   +  +   +    N                Y CIA N+ GE     ++ +Q+
Sbjct: 2574 ISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQE 2633

Query: 1570 KPVITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
             P+I    E  + +H     GD+  +     G P P V W+++ N++ +  EY I  K+ 
Sbjct: 2634 PPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRD-NRILSPPEYKI--KDD 2690

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             +++ I       +  YT  A N AG SS+ + + V   P
Sbjct: 2691 GTLV-IPGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPP 2729



 Score =  149 bits (361), Expect = 8e-34
 Identities = 176/747 (23%), Positives = 296/747 (39%), Gaps = 61/747 (8%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            I L C  VAIP P+I W   G  + P ++  V I  D     + L+I N +   EG Y  
Sbjct: 2938 IELRCPTVAIPVPEIVWYKDGHRLHPFQS-GVLISPDG----TTLRIPNAQLHDEGVYQC 2992

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWC 769
            VA N  GE      L+I      PP ++    + I V  G S  +  +  G P+PT+TW 
Sbjct: 2993 VATNVAGEEMKLFNLQIDV----PPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWT 3048

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            KNN  +     + D D   +  +    V DEGV+     NS G       +T     +  
Sbjct: 3049 KNNAFISPASIRYDIDPAGLLHIATVTVADEGVFECFVSNSAG------NVTRRIDLQVQ 3102

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             +P +   R   +T +   +++L    T  P P I W ++ + +SP E      DG    
Sbjct: 3103 VQPTITPGR-GRVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDG---- 3157

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            ++  N     D+G Y C+A N AG      +V ++V +   +    K+YE     +V LE
Sbjct: 3158 MLQINDAQPSDAGRYDCIAKNGAGADVF--KVILEVHEPPQIAETTKTYEIRVDASVELE 3215

Query: 950  CQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--- 1004
            C+       + +W  N +E+     +  +  G             D G   C+ ++    
Sbjct: 3216 CRVGGIPKPNIRWLFNGRELGAQSLK--LANGN---LKIPVVRAEDSGAYTCLAQNDAGF 3270

Query: 1005 -ETSTMLVVKET--IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKK 1060
             +   +LVV +   +P   R+  +  +     A+L    +     +V W +DG +++P  
Sbjct: 3271 AQAERILVVLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAG 3330

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQK 1117
                 E      +L I      D G Y+C+  +   +  +     V++ P       + +
Sbjct: 3331 RITMTEN----HELIIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVE 3386

Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
            +  GN+     E   G  +  + W  +G+E+   N    T DG +  L I +    D+G 
Sbjct: 3387 LAAGNRLELICEAI-GVPMPDIAWLVNGTEM-IPN--PPTFDG-RSVLAIGNVQKSDSGT 3441

Query: 1176 YSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKK 1232
            Y C   N     TAI  V         R+P    +     A L   +  D   +VTW K 
Sbjct: 3442 YMCRAENILGVRTAITAVRVRVPPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKN 3501

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV 1291
               +  T+     SD    +LII      D   Y C  L+     ++   + ++  P  V
Sbjct: 3502 NRPVALTDTMQQSSD---GSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRPMFV 3558

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               +   +  G +V L    Q  P+P+  W    +  +     + +I   + +L I   +
Sbjct: 3559 VEPQNTTVSHGENVLLDCIAQGEPEPSMRW--QKEGFRVLPVGRVAI-LPNNTLKIVAAQ 3615

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL 1378
             TD+G Y    EN  G A + +++T++
Sbjct: 3616 LTDSGAYMCLAENQMGRAVMTIHLTVM 3642



 Score =  140 bits (340), Expect = 3e-31
 Identities = 237/1079 (21%), Positives = 395/1079 (36%), Gaps = 76/1079 (7%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G  P   + P    V+ G ++ + C  +  P P + W   G+  + D N  + +  D ++
Sbjct: 885  GSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHL-DINPRITMTEDGNL 943

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            +     I +++    GTY  VA N  G       L+I T   +P       + ++V + +
Sbjct: 944  F-----IRDMQVEDSGTYVCVAHNEHGSTEASAQLRI-TNLIQPQISATSQEEVVVVEDD 997

Query: 751  SVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
             V+    + GNP PT+TW  +++ +  +  P        S+ I +   + D G YT  AE
Sbjct: 998  VVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPDGSLGI-RGAVMSDAGNYTCVAE 1056

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N+ G       I V         PP         TV    ++ L+     +P P I W +
Sbjct: 1057 NAIGNDTKITRIRVH-------NPPSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIK 1109

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            N + I P+  + Q+       L ++ V +E D+G Y C  SN AG S     + I V   
Sbjct: 1110 NGQTI-PNLGLHQS------ALTLSYV-TEQDAGTYICRVSNLAGFSEIEITLFILVPPA 1161

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                         +G +V L C    T   +    K  +   +                 
Sbjct: 1162 HEGVETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQ 1221

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVE-INSET 1044
                + G  +C+  +   +    V+ TI   P       ++ V      IL  E      
Sbjct: 1222 MSVAEEGQYRCVASNIAGNVSKDVRITILVPPSIEPGNTEYAVVAGGSIILSCEAYGIPM 1281

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV 1102
             +VVW++DG  +            G    L I  TS    G Y+C++ +E  S    +T+
Sbjct: 1282 PEVVWQKDGAQLSIATRNVRILDLG---SLQIDVTSEEHTGTYTCLVTNEAGSTNRLITL 1338

Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
             V +PP I        V +G         T      + W K+G  I   N     +D   
Sbjct: 1339 SVIVPPRIFDGQTQYTVVQGQAIILHCPATGTPPPTITWSKEGIAIPL-NDPHYDVDEIA 1397

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
              L ++     D G Y C V N   +    +   S++    + E +    +     TV +
Sbjct: 1398 GTLTMFGVLPTDFGTYKCVVRNDGGSVYKDI-TLSVHVAPVIEEAVEETFSITIGQTVSL 1456

Query: 1221 PDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AK 1274
            P E        VTWYK  + I  T    +  D    +L I      D   Y CV  + A 
Sbjct: 1457 PCEVTGTPPPIVTWYKSGNPISVTSSMVITQD----SLDIYSTRPFDTGIYQCVASNVAG 1512

Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            + T+    +V  PP I D       + G+ + L       P P+  W  + + +    + 
Sbjct: 1513 NVTRNFRLIVMIPPSIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLG--TYN 1570

Query: 1335 KPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393
             P +   +  +L I  V+  D+G Y   + N+ G A   + +T+   P     P     D
Sbjct: 1571 DPRLRKTAFGTLQIVNVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSP-----D 1625

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
            S +  I           T+      +   D T W+        Q  ++   T S+    A
Sbjct: 1626 SYTSLI-------RNPVTLQCLAAGFPPPDVT-WLK-NGAPLNQEDVRYYITPSNSLLIA 1676

Query: 1454 YAVNE---VDISDASETTEY-YKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGV 1508
              + E   +   + S T  + YK ++ T    PT +     +     N  + L C     
Sbjct: 1677 STMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSY 1736

Query: 1509 PQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
            P P +TW +DG+ +    + Y                   Y CIA N  G +  +  + +
Sbjct: 1737 PPPTITWLKDGRVIPYTNSHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINV 1796

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
            Q  P I+   + I     +G    +     G+P P  +W K+G +L  D +      ++ 
Sbjct: 1797 QVPPYISPGPDTITA--YLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYD-DSRFHKLDEG 1853

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPVIMREISRESVTI 1685
            S+I I +++   +  Y     N AG  +  +TL V D P    E P +M +I    V I
Sbjct: 1854 SLI-ISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVRI 1911



 Score =  133 bits (321), Expect = 6e-29
 Identities = 214/966 (22%), Positives = 362/966 (37%), Gaps = 87/966 (9%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
            +PP    P ++     G   +L+  V      T+ W +   P+      S+  + + TI 
Sbjct: 526  DPPTTFMPRRTPGY-YGMDAVLTCDVESMIPFTVRWMRRGTPLDGPIEFSETGSATWTI- 583

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            K    + EGVY+  AEN EG A +   + + EP      PP+    +    +     + +
Sbjct: 584  KNSDSRIEGVYSCIAENEEGSARSETYLDITEP------PPVIARPYNTSVLPGSDGV-M 636

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
               ++     +ITW + N ++S       +    N  LVI +V    D+G Y+C A N  
Sbjct: 637  SCFISSTVEYNITWDKPNTLVSLQGHNRVSL-MNNGSLVIQDVHPG-DAGSYRCRAWNEG 694

Query: 913  GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKE---I 967
            G +     V + V++   +   Q +      + + L C  +       +W  + +E   +
Sbjct: 695  GVTEE--HVYLYVQERPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDGQELPIV 752

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQ- 1024
             G    EII +              D G+  C+  +   S +L V  +   P  I+  Q 
Sbjct: 753  PGTRRGEIIHQ-------IFNASREDQGIYTCLASNTAGSDLLNVYVSYHEPPRIQMTQY 805

Query: 1025 DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
             +       A L    +     ++ W +    +     +  + +      L I      D
Sbjct: 806  RYLTPPSQKATLSCPTSGVPPPEITWFKGDRDL----TRVTYTRIWPNGDLDIMGVQDSD 861

Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKG-NKATFEIELTKGDALVRW 1139
             G Y+C   +E+     TV   V   P I+    +  VN G N +   I +      V W
Sbjct: 862  SGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTW 921

Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-- 1192
             K G S +  +  I +T DG    L I D  ++D+G Y C    E G+++ +A L +   
Sbjct: 922  RKVGQSHLDINPRITMTEDG---NLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNL 978

Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI--EDTEKFTLISDVK 1249
             +P I+ T +  E ++V  +      V   +    VTW+     +  E + +  L  D  
Sbjct: 979  IQPQISATSQ-EEVVVVEDDVVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPD-- 1035

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
              +L IR     D   YTCV  +A  + TK+    V  PP I   E  Y +     VTLL
Sbjct: 1036 -GSLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGTETSYTVIHHESVTLL 1094

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                  P P  EWI N + I       P++    ++LT+  V   DAG Y  R+ N  G 
Sbjct: 1095 CPAAGHPPPLIEWIKNGQTI-------PNLGLHQSALTLSYVTEQDAGTYICRVSNLAGF 1147

Query: 1369 ADVEMNVTILDKPS-----PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
            +++E+ + IL  P+       G  N+ + DS ++  C      T    I ++       +
Sbjct: 1148 SEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLP-C--NVRGTPPPQISWFKDNLPLPE 1204

Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
                  V   T     IQ +      ++R  A N              K ++ T +  P+
Sbjct: 1205 AGRNFYVN--TDGGLVIQQMSVAEEGQYRCVASNIAG--------NVSKDVRITILVPPS 1254

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXX 1541
            +E             I L+C   G+P P+V W +DG +L  A       +          
Sbjct: 1255 IEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILDLGSLQIDVTS 1314

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C+  N+ G       + +   P   I +   +     G   ++     G PP
Sbjct: 1315 EEHTGTYTCLVTNEAGSTNRLITLSVIVPP--RIFDGQTQYTVVQGQAIILHCPATGTPP 1372

Query: 1602 PEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            P + W K G  +  ND  Y++   E    + +  +  +    Y     N  G+   ++TL
Sbjct: 1373 PTITWSKEGIAIPLNDPHYDV--DEIAGTLTMFGVLPTDFGTYKCVVRNDGGSVYKDITL 1430

Query: 1661 KVYDKP 1666
             V+  P
Sbjct: 1431 SVHVAP 1436



 Score =  114 bits (274), Expect = 3e-23
 Identities = 81/298 (27%), Positives = 131/298 (43%), Gaps = 24/298 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + PTF+  P    +  G+ + L C  + +P PDIAWL  G E++P+              
Sbjct: 3374 VAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGR------- 3426

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             SVL I NV+K   GTY   A N  G  +    ++++     PP++        +  GE 
Sbjct: 3427 -SVLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRV----PPRIHRIPSDTTLTLGER 3481

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             +L+  V G+P+P +TW KNN+PV    T       S+ I+ P  + D G Y  +A N  
Sbjct: 3482 AVLNCAVNGDPKPEVTWLKNNRPVALTDTMQQSSDGSL-IIAPTAISDAGFYKCQALNLY 3540

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G+ E S  + ++         P+F+   Q  TV     + L       P PS+ W +   
Sbjct: 3541 GLDEVSYHLEIQ-------SRPMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKEGF 3593

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + P   +        +++V   +    DSG Y C+A N  G++     +T+  E +T
Sbjct: 3594 RVLPVGRVA-ILPNNTLKIVAAQL---TDSGAYMCLAENQMGRAVMTIHLTVMGECLT 3647



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 123/568 (21%), Positives = 208/568 (36%), Gaps = 51/568 (8%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
            VRW + G+ +     I+ +  G      I + D    G YSC    E G+++    L + 
Sbjct: 558  VRWMRRGTPLD--GPIEFSETGSAT-WTIKNSDSRIEGVYSCIAENEEGSARSETYLDIT 614

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            EP     +  P    V   +D  ++  I      ++TW K  +++   +    +S +   
Sbjct: 615  EPPP--VIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVS-LQGHNRVSLMNNG 671

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            +L+I+     D   Y C   +    T+  V + V+  P+I  Y+         ++TL   
Sbjct: 672  SLVIQDVHPGDAGSYRCRAWNEGGVTEEHVYLYVQERPQINAYQGNVTFTSSQNITLRCS 731

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
               +P P   W+ + + +     T+           I      D GIY     N  G   
Sbjct: 732  ANGYPHPELRWLKDGQELPIVPGTRRG----EIIHQIFNASREDQGIYTCLASNTAGSDL 787

Query: 1371 VEMNVTILDKP----------SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
            + + V+  + P          +PP +   L   +S +      PE T             
Sbjct: 788  LNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGV----PPPEITWFKG--------- 834

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
            + D T     +        I  ++ + S  +  YA NE  +   SET        E    
Sbjct: 835  DRDLTRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGV--VSETVHL-----EVG-S 886

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXX 1538
            SP + +P  ++      ++ +TCI  G P P VTW + G+       + T          
Sbjct: 887  SPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLDINPRITMTEDGNLFIR 946

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA-VIE 1597
                     Y C+A N+HG  E S  + I       IS    ++   V D+ +V   VI 
Sbjct: 947  DMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQISATSQEEVVVVEDDVVVRCNVIS 1006

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            G PPP V W+ +  +L  +    +      S + I+    S +  YT  A N  G  +  
Sbjct: 1007 GNPPPTVTWFHSSERLYPEYSPRLELFPDGS-LGIRGAVMSDAGNYTCVAENAIGNDTKI 1065

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTI 1685
              ++V++ PS          I  ESVT+
Sbjct: 1066 TRIRVHNPPSISGTETSYTVIHHESVTL 1093



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            V +++     +G  ++  C   GYP+P++ WFR   I+ P +     Y   +  TLVI  
Sbjct: 2643 VNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPPE-----YKIKDDGTLVIPG 2697

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              P DAG +TC A N AG +S +  + V  P
Sbjct: 2698 AMPFDAGVYTCSAVNEAGNSSISINVTVMVP 2728



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 3/131 (2%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            ++API ++      +   + V  +C   G+P P +TW +  A +   +D + Y    N  
Sbjct: 1615 NLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLN-QEDVRYYITPSN-- 1671

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
            +L+I     ED+G +TC   N AG      EL V  P +   S  T              
Sbjct: 1672 SLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPC 1731

Query: 627  DILEGIPPTFS 637
            ++    PPT +
Sbjct: 1732 EVQSYPPPTIT 1742



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            VE     +   G +V   C V G P PQI+WF+    + P      Y + D    LVI++
Sbjct: 1165 VETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLPL-PEAGRNFYVNTD--GGLVIQQ 1221

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            +   + G + CVA N AG  S    + +  P S
Sbjct: 1222 MSVAEEGQYRCVASNIAGNVSKDVRITILVPPS 1254



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G +   +C+  G P+P +TW +  A I P+    + YD D    L I  V   D G F C
Sbjct: 3028 GGSTTIDCESYGVPKPTVTWTKNNAFISPA---SIRYDIDPAGLLHIATVTVADEGVFEC 3084

Query: 584  VAKNAAGFASSTTELIVE 601
               N+AG  +   +L V+
Sbjct: 3085 FVSNSAGNVTRRIDLQVQ 3102



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%)

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
            + G P P +TWF  +  + P    ++    D   +L IR     DAG +TCVA+NA G  
Sbjct: 1005 ISGNPPPTVTWFHSSERLYPEYSPRLELFPDG--SLGIRGAVMSDAGNYTCVAENAIGND 1062

Query: 593  SSTTELIVEAPLSDHGSE 610
            +  T + V  P S  G+E
Sbjct: 1063 TKITRIRVHNPPSISGTE 1080



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            T  G +V+  C   G P P+I W +    + P + F +  D      L I +  P DAG 
Sbjct: 3116 TQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISD----GMLQINDAQPSDAGR 3171

Query: 581  FTCVAKNAAG 590
            + C+AKN AG
Sbjct: 3172 YDCIAKNGAG 3181



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 31/99 (31%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 508  MAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            +AP+  E +    +   G TV   C+V G P P +TW++    I  +    +  D     
Sbjct: 1434 VAPVIEEAVEETFSITIGQTVSLPCEVTGTPPPIVTWYKSGNPISVTSSMVITQD----- 1488

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            +L I    P D G + CVA N AG  +    LIV  P S
Sbjct: 1489 SLDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIPPS 1527



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            T  G+ ++ EC+ +G P P ITW++    +    D ++        TL I  V  ED+G 
Sbjct: 1537 TEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDPRL--RKTAFGTLQIVNVDQEDSGE 1594

Query: 581  FTCVAKNAAGFASSTTELIVE-APL 604
            + C   N AG AS    L V  AP+
Sbjct: 1595 YACYVSNDAGKASKFVTLTVNLAPI 1619



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 6/76 (7%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            ++V+ EC+V G P+P I W      +  +Q  ++   + N+   V+R    ED+G +TC+
Sbjct: 3210 ASVELECRVGGIPKPNIRWLFNGRELG-AQSLKLA--NGNLKIPVVRA---EDSGAYTCL 3263

Query: 585  AKNAAGFASSTTELIV 600
            A+N AGFA +   L+V
Sbjct: 3264 AQNDAGFAQAERILVV 3279



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%)

Query: 503  SEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY 560
            S E  + P+   + + + T   G ++   C+  G P  +I W F   AI   S     Y+
Sbjct: 2074 SLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAI---SSQNSRYH 2130

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
               N  +L +REV   D+G FTC+AKN+AG  +    + V  P S
Sbjct: 2131 IASN-GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPS 2174



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 4/80 (5%)

Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
           TP        C   G P P+ITWF+    +      +++ + D    L I  V   D+G+
Sbjct: 809 TPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNGD----LDIMGVQDSDSGS 864

Query: 581 FTCVAKNAAGFASSTTELIV 600
           +TC A N AG  S T  L V
Sbjct: 865 YTCYATNEAGVVSETVHLEV 884



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C+ EG P P ITW R     KP +    +Y      +L I      D+G + CVA N  G
Sbjct: 2473 CEAEGNPTPTITWERDN---KPLELRDSHYLIGEDGSLRITAPQHTDSGGYVCVASNNIG 2529

Query: 591  FASSTTELIVEAP 603
            +A     L+V+ P
Sbjct: 2530 YAIKNFHLVVKIP 2542



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 521  TPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
            T +  TV  EC V + +P  ++TW++    I    D  ++++  + + L +  + PEDAG
Sbjct: 1998 TEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTS-LRLPYLRPEDAG 2056

Query: 580  TFTCVAKNAAG 590
             + C A N  G
Sbjct: 2057 HYHCEATNGQG 2067



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 5/115 (4%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS--TVQFECQV-EGYPRPQITWFRQ 546
            E  + + V  +    E S+AP       P   P G   +++ +C V + +P P I W++ 
Sbjct: 2336 EATNAVGVLSRDIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKG 2395

Query: 547  TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
               +   Q+  +   D  + TL I  V   +AG + C A N AG AS    + V+
Sbjct: 2396 DETLT-GQEEAVTIKDQGI-TLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQ 2448



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 3/88 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            D ST Q  C   GYP P I W++   ++  ++      +   V  L I  V    AG FT
Sbjct: 2841 DDST-QLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEV--LRINRVNRIHAGQFT 2897

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSE 610
            CVA +  G  S +  L V       G+E
Sbjct: 2898 CVASSIVGNISKSYVLNVRVRPEIEGAE 2925



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 7/101 (6%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVA 566
            +AP F           G+ ++  C+  G P P I W    T +I     F      D  +
Sbjct: 3374 VAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTF------DGRS 3427

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
             L I  V   D+GT+ C A+N  G  ++ T + V  P   H
Sbjct: 3428 VLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRVPPRIH 3468



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V   C   G+P P +TW +   + +   D            L IR++  ED+GT+ C
Sbjct: 902 GMNVSVTCIAMGHPPPAVTWRK---VGQSHLDINPRITMTEDGNLFIRDMQVEDSGTYVC 958

Query: 584 VAKNAAGFASSTTEL 598
           VA N  G   ++ +L
Sbjct: 959 VAHNEHGSTEASAQL 973



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 8/109 (7%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            +V   C   G+P P I W +    I P+            + L +  V  +DAGT+ C  
Sbjct: 1090 SVTLLCPAAGHPPPLIEWIKNGQTI-PNLGLHQ-------SALTLSYVTEQDAGTYICRV 1141

Query: 586  KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP 634
             N AGF+     L +  P +  G E T                + G PP
Sbjct: 1142 SNLAGFSEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLPCNVRGTPP 1190



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G ++   C+  G P P++ W +  A +  +       D   + +L I     E  GT+TC
Sbjct: 1267 GGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILD---LGSLQIDVTSEEHTGTYTC 1323

Query: 584  VAKNAAGFASS--TTELIVEAPLSDHGSEMTV 613
            +  N AG  +   T  +IV   + D  ++ TV
Sbjct: 1324 LVTNEAGSTNRLITLSVIVPPRIFDGQTQYTV 1355



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G      C V G P+P++TW +    +  +   Q   D     +L+I      DAG + C
Sbjct: 3479 GERAVLNCAVNGDPKPEVTWLKNNRPVALTDTMQQSSD----GSLIIAPTAISDAGFYKC 3534

Query: 584  VAKNAAGFASSTTELIVEA 602
             A N  G    +  L +++
Sbjct: 3535 QALNLYGLDEVSYHLEIQS 3553



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+FV + +      G  V  +C  +G P P + W ++   + P     +    +N   +V
Sbjct: 3555 PMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKEGFRVLPVGRVAIL--PNNTLKIV 3612

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              ++   D+G + C+A+N  G A  T  L V
Sbjct: 3613 AAQL--TDSGAYMCLAENQMGRAVMTIHLTV 3641


>UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Rep:
            Hemicentin precursor - Caenorhabditis elegans
          Length = 5198

 Score =  213 bits (520), Expect = 4e-53
 Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +  EC +E      ITW RQ    K  Q         + + L I +  PEDA +++C
Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            +A N AG A +  ++ V  P    G   +                 EGIPP         
Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
                             PE  I+W   G+ I+    ++   + D+      L+I N+K  
Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
            QEG YT VA N+ G A     ++I     EPP+V+   + M V +G    +  +V GNP 
Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            P + W K+ +P  +          S   L+   + D G YT  A N  G ++T+  + V 
Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                    PP   +  + +  KE  T  +  +VT  PVP +TW RN + I       + F
Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942
               N  L I N  +  D G Y C+ASN AG +   A   IDV  K TF  H + ++   E
Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313

Query: 943  GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            G++  +EC+   H   T  W    +  + MD+  II   R            D G+  C+
Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370

Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054
                    +Q+    +  K  I E I +     V   ++ +    + + T  V W+R G+
Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111
               P  +++       ++   I + +  D G+YSCI  +E+    T     V   P  + 
Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485

Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
            +  N  +V + +  T +  +T      + WF+    +   +   ++ DG    + I    
Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543

Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223
            L D G+Y C    E G S    IL +   P I+ +  +   + + A T  YL   I    
Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
              DV W K    I  T+   +++     T  I      DQ  YTC   +   K++    +
Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661

Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335
            +V+  PP+   +  +  IKR G  +TL    +      D+     W  +S+ +       
Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
              I      LTI +    +AG+Y     N  G A +E  V IL   SPP    +++I  +
Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773

Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445
             +     +P+   N  TI+   V      + +W+ + K +T  +          +Q L+T
Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828

Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
            +S +  ++   A N+  + +     + +       + S   + P+K +     E I L C
Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880

Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
               G P P++ W + G  +      A+ + +                 Y C A N  G  
Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
            E S  V +   P I     D+  +        +  + +G P P++ W  NG  L +    
Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             IT    ++ I+I  +  S    YT  A N AG+ ++   + V   P
Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045



 Score =  194 bits (473), Expect = 2e-47
 Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PTF        + EG    +EC++   P+P I+WL KG      +NI ++   D      
Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I   ++F  G YT VA N  G++     + + T       + +  K++    G  +I
Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L   V+GNP PT+TW + +    A+P  S    H  TI+    +K   V T  A     I
Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            A   A         E    P F+ +   +  V E  TI +   VT  P+PSI+W+R ++ 
Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +   +  + + DG +I +   N     D G Y C ASN AG S     + I V       
Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578

Query: 933  HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
            ++  +      +T+ LEC  S        W  N  +I+  D R I+ +            
Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637

Query: 991  XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040
              D G   C   +   + +    +   + PEF I   Q    +E D   L        +I
Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697

Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
              +  DV W +D   +     +  D    G  RKL I   S+ + G Y+CI  + +  A 
Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755

Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153
            +   VE+  PP I I+R   Q     N+ T       G     ++W K+G E+    +I+
Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
            +   G  Q L+I   D D AG++SC    + G  +   +L V  P +  +++    I   
Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              T         +    + W K  S+I D+     IS +K   L I    + D  +YTC 
Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931

Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
             L+A  T++  V V V  PP+I     +   R+     +TL    Q  P P   W +N  
Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991

Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382
             +    H+ P I   S S  + I  V  +D G+Y    EN  G  ++  NV ++  P  S
Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441
              G   ++E + + I  C  E         + ++     ++T     V+ +T     +I 
Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
              ++  S  +   A NE   +  + T E   V+   KI + T       +T        L
Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
             C   G P P ++W  +G  +K  +  +                   Y+C A ND G   
Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216

Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                V     P I+ S N  I      G E ++   IE     E  W KNG  L      
Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            N+   E   +I+I   + S   +Y+  A+N AG ++ +  L V   P   E P
Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324



 Score =  187 bits (456), Expect = 3e-45
 Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%)

Query: 648  GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            G DI L C L    +      W   G E   D   +V I SD H     L IT+ K    
Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763
            G Y     N  G+A   + L +     EPP  +EP+   +  +     +IL  QV GNP+
Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822
            PT+ W  +   V     KS     S+++L+ +K+  +    +  AEN  G A     I  
Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820

Query: 823  EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
                 +N   P F N   + T+ +E  TI L   V+      ITW +    ++ ++ I  
Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
             F  +N  L I N + + +   Y CVA+N+AG+ S    V + V  +  +K+   + E  
Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928

Query: 942  EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            EG+ +IL C    + T + KW  N+ ++     +E +                  GV KC
Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984

Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053
               +   Q   T+ V   T P F   L + E+       + +E + + A    + W  +G
Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110
            +    + +       G  R L+I +    D G Y+C + +E+  A  T    V++PP I+
Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102

Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
                   V + N      E+T K + +V W KDG  +     +Q+  +G  Q+ KI   +
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224
            +   G Y C   N   TA ++ +   I   + + + I  +V A     L  + P   D+ 
Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219

Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280
                + W +    I+ + E   +      R L I   TE+D+ +Y+C V  DA   +   
Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279

Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336
               V  PP I+  D ++       S VTL       P+P+  W  + + I  +      P
Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394
            + +     L I +++  DAG Y    +N+ G    DV +NV  + K    G P+  E   
Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            +   +    P        I ++   + + + +++   +    +  +  L+   S ++   
Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512
            A NE     A      +KV   + + +P+ ++P  ++ IT        L C   G P P 
Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509

Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            +TW +DG  ++       ++                 Y CIA N  G  +    + +   
Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569

Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626
            PVI     E +        E    +   G+   +V W K+G  +  D    +  I     
Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
               +     ++S S +YT    N AG +       V D PS
Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667



 Score =  187 bits (456), Expect = 3e-45
 Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  + K   +  G  + L+C     P P I ++  G+ +   + + +          S
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I N +K  EG YT +A N+ G +   +++++      PP++ +   ++ V+ G+ + 
Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961

Query: 754  LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            L   +       ITW +   K  +  +  +S  D   + I++    +D   Y+  A N  
Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G AE    +TV  P      P +F + F    +    T+++  R    P P I+W+ + +
Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930
             I     +T  +   ++ L I N+      G Y CVA N AG++     V I +  +V  
Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131

Query: 931  VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987
               + +     EG+   + C+   +      W  + +  +     +++Q   +       
Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184

Query: 988  XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044
                 D G   CI   K  E+ T   V+  +P  I  + +  + KE +  ++  ++    
Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244

Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102
               V W+R+G+         + E+   +  L+IRN +  DEG+YSCI  +E+ TA     
Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293

Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
              V   P   T      + +G  A  E ++       + W K G      N   + +  +
Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213
               L I      D G Y+C   NS     +   +    +P I+ T+ + P+ +   A  +
Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407

Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              L   +  + T  VTW +    + +  + T++++     L I   T +D  +Y+C+ ++
Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464

Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
                 TT    EV+  P  +      Y +     +T+     + P P+  W    K +  
Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
              + + SI    + +TI K + +D G Y  R  N  G +D+++ + IL  P    K NI+
Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581

Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
                + +   I  + P +      + +     +I+ T+   +         I+N++    
Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505
             R+   A N    +    + +     + +     PT+++    IT T P +  E +    
Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701

Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
              V   K +   DG        + + R               Y CIA N  GE      V
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             I   PVI IS  D++ +  V    ++   + G P P + W KNG ++ +D+  NI   E
Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +  V++I      H+ K++  A N AG   +E+ L V+  P
Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859



 Score =  181 bits (440), Expect = 2e-43
 Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%)

Query: 632  IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +PPT     K K +   E S + L C     PEPDI W FK  E +  ENI+  I +   
Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
            +  + LKIT +K+   G YT  A N  G     + + + T  K E   +    +S   +Q
Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807
             E V++S  V   P   ITW K  KP+++    K+  +   + + K ++  D   YT  A
Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G  +    +++      + + P  + R   ITV       L      +P P+ITW 
Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++   I P++     FD    +L I+  +   D G Y C+A+NS G       + + +  
Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981
            V   +  +++    EG +  L C ++ T V  +W       N+  + G    +I   G+ 
Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038
                       D G   CIV++       +    +   P    +L    + +  V    V
Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686

Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            EIN     S    V W  D + ++P    Y+    G   K+    + V   G Y+C  ++
Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744

Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148
                A    +  V  PP      +      G+    T   E +   + V W      +Q 
Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203
            +  I       ++ L + +  LDD G Y C   N      K   ++ +E P      +L 
Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
              IL    T        P  T  + + K    + ++++  +I      TL+I    ++ +
Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917

Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
              YTC+  +   +S   + VEV+  PPK+        ++ G  +TL    +     +  W
Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
                    +      S   KS  L I +    DA  Y     N+ G A+    VT+   P
Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035

Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
               G   +  EI + +        E      I +++ + + I     ++ K        I
Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
             N+K N   R+   A N+   +  +E   Y ++      + P V    + +         
Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559
            + C   G P+P V W +DG+   +    +  +                Y CIA N  GE 
Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
            +T+  V +   P   I +E+   + K G+ ++V   + G P P V W +NG ++E   ++
Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            N        V+ I+   R+   KY+  ASN AGT+  +  + V+ KP+          + 
Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313

Query: 1680 RESVTIEWK 1688
             ES  IE K
Sbjct: 3314 GESAKIECK 3322



 Score =  180 bits (437), Expect = 5e-43
 Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP      +   V EG    + C +   PEP + WL  GE    D      ++    +  
Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            S L +        GTYT +A N+ GE+     +++      PP++ +  + +  ++G + 
Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            ++  QV G P P +TW +N K ++          + +  ++     DEG Y+  A N  G
Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286

Query: 813  IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
             A    +I V  +PT E  E            + E  + K+  ++  +P P+I+W +   
Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
              +  + I  +  G+ + ++        D G Y CVA+NS G S    +V +   K    
Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393

Query: 932  KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            + + ++ +   G  +IL+C    + T +  W      +       I+             
Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450

Query: 990  XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044
               D G   CI V +    T     E I  P F+RK  + +EV E D   ++  + S   
Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
              + W R G+      ++Y     G    + I    + D G+Y C   +E+ T+++ +  
Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567

Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158
             + +PP+I     + N           E  ++      V W K+G +I  ++  ++ +  
Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209
              +   I +  + D G Y+C   N    A       +L+  E  I+ T      E   + 
Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
                  L  +I D+ +DV+W K    ++ D      ISD   R L I + + ++   YTC
Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            + L+      L+ +V    P ++D  R   + ++       +       P P+ +W+ N 
Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
            K +   ++ +  I  +   L I + ++  AG +    EN+ G  ++EM + +   P    
Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863

Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
            K  N ++    +I +  +   N     + +        D+ +   + ++   +  I +LK
Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
                  +   A+N    S+AS + +   V+   +I    ++   +       + + L C+
Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975

Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
              G P P++ W  +G  L   T   T   +                Y C A N  G    
Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               V + Q PV  ISN   KQ  + G+  ++  ++EG P P+V W +NGN++E   +  +
Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                   ++ I E +   S  Y   A+N AG++    TL+V   P
Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136



 Score =  177 bits (431), Expect = 3e-42
 Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            V  +C   G P P+I W +   ++    + +  Y       L+I +   ED G FTC+A+
Sbjct: 810  VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867

Query: 587  NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
            N  G  S +T L+V   +S                      +L  +PP        + + 
Sbjct: 868  NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899

Query: 647  EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            EG D+ L C +V   P+P I W+ K ++ V +E  ++ IE       S+L++       E
Sbjct: 900  EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953

Query: 706  GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747
            G YT +AV+  G ++L I V  IK  E     E   V +P  S +             V 
Sbjct: 954  GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805
             GE   +   V G P P ITW  + +P+   P   D   T   T++  K  K   GVYT 
Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            +A NS G  E    I +          P+         +       +   V  +P P IT
Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W      +   +  T+    E+  L I NV +E   G + C A N+AG  +    +T+  
Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
                  ++ +K     +   ++LEC        V    Y  +K  S +    I ++G   
Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      + GV  C V +      L    T+ E  + + +       V    +EI  
Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292

Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
                V      W ++G  +K  + K+  +  G +R   I     +D G Y+C++ +E+ T
Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349

Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
            +++T    V+ PP I+   Q N     G++   +  +     A V WF+ G  I      
Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207
            +  +      L I    ++DA  Y+C+  N   K  A   +  +  P I     + +  +
Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467

Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
              ++  +       +    ++WY   K +I+D   +    D  KR L + K    D   Y
Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525

Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             CV  +A        +V    P  +D   Y+++   K G +VTL      FP P   W+V
Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585

Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            +  +++  K  K  ++ +   +L    V     G Y    ++     D+++ +++L  P 
Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
                 N+       I++  D    + + T   + +   E D  + + + +    +  I +
Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
             K  ++ ++     N    +  +E T    V++      P  E   K I   P   I L 
Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            C   G P+P V W  DG  +  +   ++                   C A N  G     
Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621
                IQ     T  NE  ++      E +       +   ++ W K G  L END    I
Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
             T + T  + I    R H   YT  A+NTAG  S +  + V   P K +  V+  EI+
Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928



 Score =  157 bits (380), Expect = 4e-36
 Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751
            +   + +K   G YT +  N  GEA       +     +PP + + L S  ++       
Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685

Query: 752  VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            V ++  V G+P P + W  ++KP++    A    ++G+T  I      +V+  G YT +A
Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866
            +N+ G A    ++ V         PP F    +E+  +   T+ L      + P+ S+ W
Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            + ++E +  +  IT  +      L +TN+  + D G Y C A N AG +    ++ + +E
Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984
               F+   QK Y    GK + L+C  + T   +  +  + K ++  D  +II        
Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907

Query: 985  XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                      G   CI +++       M+V     P+  ++  + EV+  D   LE  I 
Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967

Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
              +   + W R  +  K  +     +      KLYI   +  D   YSCI  +++  AE 
Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025

Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154
                 V  PP+I     +      +  T EI   T+G     + WF DG  I     +  
Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            T       L+I +   +  G Y+C    + G ++    + + EP     +   E + V  
Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140

Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
                 +  E+   P+    V W K  +    D  +F+     K   L +R+ T  D   Y
Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194

Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
            TC+  +   +S T   VEV+  PP+I D ER  + K G+   +       P P   W  N
Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
             K           I+  +  L I+     D G Y     N  G A  +  + +  KP+  
Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438
                  E   ++ NI        G S  I   ++     T  W+      ++ NI  +  
Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497
                L    + RF       V  +   ++ + +KV   TK     T+++  K +      
Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406

Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            +I L C   G P P VTW R D      ++ T  N                Y CIA N+ 
Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G + T     +  KP       ++ +  +  D   +   +   P P + W++    +   
Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
              Y+I+     S I I + K S   KY   ASN AGTS +++ LK+   P   +  +I  
Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
             ++  + TI  + P+   G+        K+  D N       + ++ ET+ I+ +    +
Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641

Query: 1737 YMFRVIAQNPVG 1748
              +   A N  G
Sbjct: 3642 GRYTCTATNRGG 3653



 Score =  155 bits (377), Expect = 1e-35
 Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L I + K    G+Y     N  G A+    L ++     PP ++       V +  S++L
Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118

Query: 755  SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
              +V G P P +TW K+ +PV   K++   S+G    I      ++  +G Y   A+N  
Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868
            G AE S  + +          P+     + I    KG     K      +N    I W R
Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228

Query: 869  NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            N + I   +E         +  L I NV +E D G Y C   N AG++S   + T+ V  
Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287

Query: 928  VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983
               +    K+    E  TV L C  +        W+ + + I   +  +II  G      
Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038
                     D G   C   +   S    V     TIP+  +     D+E ++ +  ++  
Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407

Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
             + +   A + W + G   KP ++    +   + +KLY+      D  +Y+CI  +E+ T
Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464

Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
                 +V+++  P    P I+ R+    VN GN +T      KG     + W KDG+ I+
Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203
              N   +  D  +Q L+I   +  D G Y+C     VG+      L V  P +    R  
Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259
            E + V     + L  +     +DV W K    I +DT   + F  I    K+   +    
Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636

Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315
            + D   YTC++ + A    KL    V  PP I D      I+       V +       P
Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P   W+ + K ++        + +   +L I + +   AG Y    +NN G A  +  V
Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755

Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433
             +   P      +  +  +  + +  C    E++   + +Y+    + +      S    
Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813

Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
             +   ++ N++ +    +   AVNE  I     T +++K+I    I++P      K    
Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
               + + L C   G P P + + +DGK+L  +                      Y CIA 
Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N  G  E   +V +   P   +S E I  + + GD   +   IE      + W +   K 
Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +   +    +    S + I +     +  Y+  A N AG +     + V   P
Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035



 Score =  155 bits (375), Expect = 2e-35
 Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%)

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            + +N A F    T L +     DH    T              D++  + P         
Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             ++EG +I+L C     P P   W F   ++ P E + V   ++ H     + + NV K+
Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
              G Y   A N+ G+A   I + ++T  +    + E    + V    S+ L   V     
Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035

Query: 764  PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
              I+W  N KP  A    + T + G    I      K  D G Y     N  G+A  +  
Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            + V+        PP  +N   E TV E  ++ L   VT  P P +TW ++   +   +++
Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936
                +G+  ++V   +      G Y C+A N  G     A ++ DV+ +T     K ++ 
Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198

Query: 937  SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991
                 +G  +  +C      + K    W  N + I    +   I +              
Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258

Query: 992  XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
             D G   C VK+         K T+   P  I   +D     V+   V +          
Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099
            D+ W +DGE I   +N  D    G +   +L I      D G+Y+C   + + + E    
Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377

Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
            V V+ +P      + +   ++ N +      +  +  A + W K G  +Q    ++ + +
Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437

Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212
            G  QKL ++     D+ +Y+C    E G  K    +  +  PS +    +    +   N 
Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
                       +  +TW K  + IE  +++        R L I K    DQ  YTC+  +
Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            +  +  L+  +    P ++D ER   +    G    L  D  +    + EW  +   I +
Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612

Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
                  S   I S    ++      +D+G Y   + N  G A    +  + D PS     
Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446
              +  + SS NI    P        I  VV         W+      +  ++   L  N 
Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503
             + +     V               K  K+  ++    P  EK  + +     + + LTC
Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782

Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
                 VP   V W+   + ++    T +   N                Y C A N+ G  
Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
            +    + + + P     ++       +G    +     G PPP +++ K+G +L    E 
Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            +I      S + I   ++    +YT  A N AG S  ++ ++V   P   +  + +   +
Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956

Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729
             + +T+E  P  D  G+ +T   ++  +       +   D ++   +     D ++Y   
Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015

Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767
             +N+    E +F+V    P   F ++  +  IV  T L++P
Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056



 Score =  154 bits (374), Expect = 2e-35
 Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%)

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
            A++  G  PT  + P    V+    + L+C  V IP P+I W  KG  ++   N     +
Sbjct: 785  ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                +    L IT+ +   +G +T +A N  G+ S    L + TG   P     P +  +
Sbjct: 844  ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898

Query: 746  VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
            + +G+ + LS  VV G P+P+I W K++KPV+  PT       S+  L+    KDEG YT
Sbjct: 899  I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957

Query: 805  LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847
              A +  G          I +   V   E     +PT    +      +N   ++   E 
Sbjct: 958  CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906
              I  V  V+  P P ITWY +   I+P S   T   D     L++   D    SG Y C
Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963
             A+NSAG +    + TI +     +   Q S+         + C        V T    +
Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129

Query: 964  KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
            K    G+    + ++G               G   C  ++    +T T+ +   T P   
Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182

Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
             + Q+    + D  +LE    +    V +W  +GE I  +   +   + G    L ++N 
Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239

Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134
             + + G + C    +  ++S +  +TV E  P+II+ +     V KG         T   
Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298

Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189
             ++R W K+G +++     + ++D     L+IY+ D +D G Y+C    E G S+ T  +
Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356

Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247
             V+EP I   + +     +V    +    VE       VTW+++   I  DT+ + + SD
Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304
                TL+I+  + +D   YTC   +   K+   L+V V+  P  K  D   +  IK    
Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
             +L     + P P   W +N K +   K +  + D K   L + K + TD+G+YK    N
Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531

Query: 1365 NCGHADVEMNVTIL 1378
              G       V ++
Sbjct: 1532 AAGEGSKSFQVEVI 1545



 Score =  153 bits (372), Expect = 4e-35
 Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%)

Query: 523  DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            +G  +   C V  G P+P I W +     KP ++      +   + L +R   P+D G +
Sbjct: 900  EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956

Query: 582  TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
            TC+A + AG  +ST  + V+        E               + + E      +    
Sbjct: 957  TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008

Query: 642  AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
               V +G    + C +   P P I W   G  I P+      + +D     + L +    
Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            K   G YT  A N  G+      ++I       P +     S  +   +   +   V G+
Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118

Query: 762  PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            P+P ITW  ++KP        DG   S+TI    +    G +T  A+N+ G    +  +T
Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V      NAE        QE    +   I L       P P   W    E I  S+ I  
Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
                E+  LV+ NV  E ++G + C  SN AG+ S    +T+  EK   +  +    +  
Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283

Query: 942  EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            +G T+ + C+ +    V   W  N  ++  MD ++   +              D+G   C
Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341

Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054
            +V ++  ++ +     + E    L   +     V    VE+      S  A V W R G 
Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106
             I      Y  E  G    L I++ SV D   Y+C   + +  AE    VTV+  P    
Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P+++T+   + + + +  +    +       + W+ +   +        T D K+ KL +
Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223
            +   + D+G Y C   N+      + + E  +   L   ++   V A     +T+  P  
Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574

Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
                  + W    +V+E  +K+   TL +D    TL     +   +  Y CV     +  
Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335
             + VE+      IV  +    +  G D++L  D Q          W +N     +  + +
Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392
               D     +T  K EN   G Y  R+ N+ G A+  + + +L+ P    P  + N   I
Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750

Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
             ++ I +   + + TGN    + + ++  ++D + W+  ++++  +  I+ L T  S + 
Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510
               A N+      + + +++       I +PT +      T    +E I L C    +  
Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854

Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
             ++TW + G  L    A +  +                Y C+A N  G+V     V +Q 
Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             P   I N  +  +   G+E ++T   EG P P   W  N   L   KE        T V
Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
              +  + + H+  Y   A+N  G +   + + V  KP    G
Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010



 Score =  145 bits (351), Expect = 1e-32
 Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP  SK+     V  G  + LEC +       I W     +   D  + +  +S     
Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750
             S L I         +Y+ +AVN  G A     + + T    PP++  +   +  +    
Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807
            ++ +  +  G P P I+W  + KP+  +P  T   GD    I  +KP +   EG YT  A
Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            EN  G AE    + +       +EPP  +   + + V E     +   V  NP P + W 
Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++ E  + S+ +  +     + L  T +    D G Y C+A+N AG+S    + T DVE 
Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213

Query: 928  VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983
            +    ++  ++  + +EG T ++ CQ T   V    W  N KEI   +    I+      
Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                     D G   CI  ++  + +   L+   T P F      F + E + A +E +I
Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323

Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            +      + W + G       +      RG    L I      D G Y+C+  +    +E
Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379

Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155
                V V   P    T  Q  K   G +   +  +         +K G +    N  + T
Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210
            I      LKI     +DAG+YSC    E GN +   A   + +P+  F  +      V  
Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495

Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
            N    +   +    L  ++W++    +   +++++  D    T  I K    D  +Y C 
Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553

Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323
              +   T+ + + + +  PPKI   ++   I     +     Y        PQP+  W  
Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382
            N   I     ++  +   + +  I+ V+ TD G Y     N  G A  + ++ +L  P  
Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669

Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436
                 +P I  E D+ ++       E+  +  + + +  + + +D   T+ + + +  + 
Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495
             T  Q    N+   +   A+N      A E +  +KV    +I SP V    +N   +P 
Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778

Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550
               N+   + C   G P P + W ++GK++   +     E                 + C
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            +A ND G  E   V+ +   PV+++ +++ IK    +G+   +     G P P++ W K 
Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            G+ L  D         K + + I  LK++    YT +A N AGTS   V++ V   P   
Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954

Query: 1670 EGPVIM--REISRESVTIE 1686
               + M  R  +++S+T++
Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973



 Score =  141 bits (341), Expect = 2e-31
 Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569
            I ++K + K   + STV   C   G P P ITWF+    I       +  + + N   L 
Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            I  +   DAG +TC A N+AG       + ++  P  +                      
Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
             +GIP  +  +       +   +++ C + A P   I WL  G+ +  D+ +  +  +  
Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747
             +Y   L+ T+  K     YT +A N  G       + +      + P ++   + + V 
Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             G    L     G+P PTITW K+   ++        D      +   +  D+G YT  A
Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             NS G  +    + V  P      P +   R + + V E  + +L        V  + W 
Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604

Query: 868  RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            ++   I+       +F      G+ +  +      + DSG Y C+  N AG+    AR  
Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974
             D   V     +     +   +T++      + C  S +   K  W  + K +   D   
Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031
                                G   C  ++   +     LV     P F ++ ++   +  
Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775

Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            D  +L     S    + V W    E +  +      +   + + L + N  + DEG Y C
Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833

Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
               +E+       ++ V+E  P  + + +   +  G + T +   T      + + KDG 
Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
             +  S+ + +        L I +   +  G Y+C   N    +   +    +       E
Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948

Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
            +I V       LT+E P E    + +TW ++       +     S  K + L I + T +
Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007

Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319
            D   Y+C+ + DA     +    V  PPKI  D      I   + + +    +  P P  
Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             W ++ K I +     P +  K    SL I  ++    G Y    EN  G A+ +  V I
Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123

Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
             + P       ++  ++     I     E  GN   +   ++  E  T++ +       T
Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
            + S  +L+  +      Y     + +  S+TT   +V     +  P +E   + +  +  
Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
                + C   G P P VTW R+GK+++        R               Y CIA N+ 
Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G      ++ +  KP  T    +       G+   +   I+G P P + W K G     D
Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
               NI    +   + I + +R     YT  A+N+ G S  +  + VY KP
Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390



 Score =  138 bits (335), Expect = 1e-30
 Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%)

Query: 599  IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655
            I +A   ++G  M  V             D+LE  PP F +      Q +   + I+L+C
Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759

Query: 656  RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
            ++   P+P + W   G ++    + S   +  +    S+L+I  +   +    +  A N+
Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810

Query: 716  EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774
             G AS    ++       P    E  +  I R+ E++ L   V +G+ +  ITW K   P
Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865

Query: 775  VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833
            +         D   +TIL   +   E +YT  A N+ G +++   V+    P  +NA   
Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924

Query: 834  LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
            L IN  +EI         L      NP P+  W  N   + P E +   F   N  +V+ 
Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952
            NV ++  +G YKC A+N  G++     V +   K  F   L +S  T    +++ LEC  
Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030

Query: 953  SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006
                 V   W  N K  ++  D  + +  GR            D G   C V ++    T
Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
             T  +  +  P  + +  ++ V E +  +L  E+  +   VV W +DG   +P  +    
Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118
            +     ++  I +  +  +G Y C+ +++  TAE++      +IITR   QK        
Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202

Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174
             KG    F+  +         + W ++   I   +   ++T     ++L I +   +D G
Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262

Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225
            +YSC V N          E S +F  T+ +P  I++         VE    TL       
Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315

Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278
               D+TW+K      IE+        ++    L I +  E D  +YTC   ++  + +  
Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375

Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            + V V+  P    D    +Y  ++   V +     A P     W+   K ++  K  K S
Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396
             + +   L + K+  TD+  Y     N  G    +  V++L  PS   +PNI+  I  +S
Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492

Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
             N      P     S  I ++ +   I+  +     +  + Q  I   + +   R+   A
Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551

Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
             N V   D   T E     VI   + ++  V   ++  ++E   D   T +     +  +
Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
            T  +D  +  +      +                Y CI  N  GE        +   P I
Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668

Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630
            +  +S+ +I Q         +  V+ G P P+V W  +   LE D   Y +T   +T  +
Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +I   +  H+  YT EA N  G +  +  ++V   P
Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761



 Score =  132 bits (319), Expect = 1e-28
 Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%)

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
            DI+E  PP+    P+  Y +    + L C  +  P+P++ W FKG  ++ D    V  +S
Sbjct: 606  DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                    L I +     EGTY   A+++ G+A     L + T    PP+V      M+V
Sbjct: 664  ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713

Query: 747  RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
             +G+ V    + + G P P I W KN K +         +   + I+  K  +D G Y+ 
Sbjct: 714  GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
              EN  G     A ++V          P  I     + V  +  + L       P P I 
Sbjct: 773  VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825

Query: 866  WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W + N +++   +   TQ  DG    L+IT+   E D G + C+A N+ G+ S    + +
Sbjct: 826  WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980
                   + H+    +  EG+ + L C     +   S  W  + K +   +   I  EG 
Sbjct: 882  TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939

Query: 981  XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029
                        D G   CI V     ST+ +  + I  PEF+ K +    F+     + 
Sbjct: 940  GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999

Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
            EK VA++                V   +    + W  DG  I P  N  DF        L
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056

Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
             +R       G Y+C   + +   E  T + +    +        N      F I     
Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116

Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186
            GD   ++ W  D  +  F+  + +  DG    L I + +    G ++C      GN   T
Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170

Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241
              LTV   P+IN      E I +  N D  + +E P + L      W Y+ + +      
Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
             T+  D     L+++    ++   + C +  L  + +    + V E P  I +      +
Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
             +G  + +       P+    W  N  I  K    K S+D+   +L I + +  D G Y 
Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340

Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416
              + N  G + +  +V + + P   P  + N   +    + + C+ E     + T     
Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +     DT  ++   + T     IQ+     +  +   A N    ++A+        ++ 
Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448

Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531
            T I SP ++ P  +   + + +    L C     P P+++WY + K L   KT+  T ++
Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587
            +               YKC+A N  GE   S     Q + ++ ++ ++ K K KV    G
Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646
            +E  +   + G P P++ W  +G  +E  K+Y   T     + +    +       Y   
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624

Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
            A +      ++V L V   P
Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644



 Score =  125 bits (302), Expect = 1e-26
 Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            I  T  + PKA     G +I+L+C ++  P P + W  +G++ VP+++    + +     
Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               LKI +V     G Y+ +AVN  G  +     ++  G+  P  V +      V + ++
Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + +   V   P P+I+W + +KPV      S     S   +   K+ D G Y  +A N  
Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G ++   ++ +  P +   +    I     I  +   TI L   ++  P P + W +N  
Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613

Query: 872  IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             I+ +++   + QN +   IE V        D G Y C A+N  GK+SH   + + +   
Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667

Query: 929  TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979
             F  H  +     EG T+ L C            +   W  + + + G   D+ +I  +G
Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034
            R            + G+  CI  ++  E S    V+   P  I   R     +V      
Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785

Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            I+   +       + W ++G+ +   +N     ++G + ++ +R  S H  G++SC+  +
Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842

Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149
            ++   E+ +   V  PP +  +  N     G   T     +      ++W K GS I F 
Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204
            +     I  K  +L I      D G+Y+C+  N+  T+  +V       P IN    +  
Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960

Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
               +PA     L      + +  + W     ++   T   T+ SD     + I   +  D
Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018

Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
            +  YTC   +   +  L   V+VV+ P  ++      ++  G    +    + +P P   
Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W+ N   ++        + +    LTI +  + D+GIY     N  G A     + +L  
Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135

Query: 1381 PS-PPGKPNILEIDSSS 1396
            P      P +L   S S
Sbjct: 4136 PKIITSTPGVLTPSSGS 4152



 Score =  118 bits (285), Expect = 1e-24
 Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            I LEC +  IP+PD+ W   G +I + D  + +A  ++         I NV+   +G YT
Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763
              A NR G+AS    L + +    PP+  I   +  I R+G+++ L+     A+ + +  
Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701

Query: 764  PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
              ++W K+++ +    T +     D   +TI +   +++ G+YT  A N  G A     +
Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760

Query: 821  TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             +  P      P + I+R   Q      + TI   A VT +P PSI W +N + ++  E 
Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
            I     G+ ++++ T+ D    +G + CVA N AG       + +DV     V     + 
Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868

Query: 939  ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                G+T+ L C  S       KW      I    D   I  +G             DVG
Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926

Query: 996  VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049
               C  +    TS   V  + +  PE  R   D   +   ++ + +  +        + W
Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105
              +G  +                 + I N S+ D+G Y+C    +   ++    V VV+ 
Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163
            P  +I+    ++V +G  A  E  +    A  V W ++G+ ++     ++   DG+   L
Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220
             I +    D+G Y C   N   +A    T+E       +     +L P++   + L   +
Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160

Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
               PD    ++W    + I+D E    I      TL I K  E+    Y C   +     
Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
            T +  V+ +  P       R      G++  +  + ++       W  N   +    +  
Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
             S D K   +   ++  +D G Y     N  G+A  + N+ +   P    +P    +   
Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454
                 W E        I +Y  +  E+ T   +     TK ++ I  ++  + +  +   
Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            A N V  +   E  +   +I       P V     N++T P + + L+C   G+P+P ++
Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442

Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558
            W RD          Y+                  Y CIA +D G+
Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487



 Score =  115 bits (277), Expect = 1e-23
 Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%)

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957
            D+G+Y+C   ++ G  S   RV              ++     G+   L C T     V 
Sbjct: 493  DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550

Query: 958  TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014
             +W      +    + E  +               D GV +C+ ++     T  M +   
Sbjct: 551  IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
              P      QD     ++   L  E +     +V W   G  +    N Y ++     + 
Sbjct: 609  EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130
            LYIR+ + HDEG Y C    ++  A  T   ++  PP++        V +G++ +FE + 
Sbjct: 666  LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725

Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             +G     +RWFK+G + I+  ++I++     + +L I     +DAG YSC VG +    
Sbjct: 726  IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780

Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238
             + V   S+    R+P  I  P     N +  +T++   +     ++ W K   ++   +
Sbjct: 781  DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293
              ++T ++D     L+I     +DQ ++TC+  +     ++STT +   +V   P +   
Sbjct: 838  NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892

Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
              E ++  G D+TL  V     P+P+  WI + K +++    K  I+   + L ++    
Sbjct: 893  PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404
             D G Y     +  G++ + +NV ++ KP     P G    KP I  +D   + +     
Sbjct: 951  KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010

Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458
            +   G    I  VV         W +  + IT           N+    +A   Y+ V  
Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
               ++++   E    I+   + +P +     +     ++   + C   G P+P +TW  D
Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128

Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
             K     +                     + C A N  G    +  + +   P I   N+
Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            +  +     D+ ++    + +PPP  +W   G K+  D +    T  +   + ++ +K  
Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            ++  +  + SN AG  S+  TL V++KP
Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270



 Score =  104 bits (250), Expect = 2e-20
 Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%)

Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            +TWY   + +  ++  FT+ +D    TLI+RK  +     YTC   ++    + K  + +
Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
               P I   +  + +      T+  D    P+P   W+++ K   +       + ++  S
Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            LTI  V     G +    +N  G+    + +T+   P+   + N  +I   + +I  + P
Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461
                   +  +  E ++ID+ + I           +QN+K  ++  F     N   E  +
Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
            S      E  K+I E     P V   +K  T      IE+ C   GVP+   TW ++G  
Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310

Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
            LK    K + +N                Y C+  N+ G  + +  V +Q+ P+I  S + 
Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
                  VGD   +   +E  PP  V W++ G  +  D +  +   + T VI+   ++   
Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698
            ++ YT +ASN AG +   + + V   P   +  V+ +E  +ES       P+    L ++
Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757
            + Y  +K   D+    K +D  R +  +   K       +++ +A+N  G  S++ + E 
Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544

Query: 1758 IV 1759
            IV
Sbjct: 1545 IV 1546



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++ G P  F      ++V  G D+ L C + +     I W+  GE+I+         ++ 
Sbjct: 425  VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                 SV  I  +     G Y    ++  G  S+    K +   +E P  I  ++++ V 
Sbjct: 482  -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             GE+  L           I W +    V   P      T+    +      D GVY   A
Sbjct: 533  LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N+ G++     + + EP      P       Q++    +  + L      +P P + WY
Sbjct: 593  RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645

Query: 868  -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             +   +++  +       G++ + +     +  D G Y+C A + AG+    AR T D+ 
Sbjct: 646  FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697

Query: 927  KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981
              T   V+ +Q       G  V  EC+T         +W+ N K++   D    I EG+ 
Sbjct: 698  LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037
                       D G   C+ ++     + V   +   +P  I       V  E+ V +  
Sbjct: 757  --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814

Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093
            + +     ++ W++   ++    N +Y     G+   L I +  + D+G+++CI R+   
Sbjct: 815  LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871

Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
             +S +  + V  L   ++  +   +++ +G   T    +  G     + W KD   ++  
Sbjct: 872  QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
              I+  I+G    L++   +  D G+Y+C   +    + L +    I    + PEF+  P
Sbjct: 932  PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V EG   ++EC +   P P ++WL  G  +       V   +D  M    L I   +   
Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763
             G Y   A N  G A     L++       P++I     ++    G    L   V G P 
Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165

Query: 764  PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P I+W  N   +K      DG+  H+I    T+   K  +   +Y   A+N  G      
Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
              T+E P +    P +  +  + I   E GT  ++     +     +W +N   + PS  
Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
            +  + D + I+++ T +    D G+Y C A+N AG ++   +  ++V     +    ++ 
Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327

Query: 939  ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
               +G  V L C+ S     +  WY + + ++     E     +              GV
Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386

Query: 997  IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052
              C  ++   ST   + ++    PE + +  +     +    L          V+ W RD
Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109
              I      KY          L IRN    D+G Y CI + ++     T   +V  P + 
Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134
               +  +   KG     E  + +GD
Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%)

Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            I +  L DAGEY C V    GN S  T + T E P   F +R    + VP    A+L   
Sbjct: 486  IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542

Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276
                  +++ W +  + + +        +    TL I   T  D   Y C+  +A   ST
Sbjct: 543  TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             K++++++E PP +    ++        V L  +    P+P   W    + +      K 
Sbjct: 601  RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
             +   S  L I+   + D G Y+ R  +  G A    ++ +   P      N + +    
Sbjct: 658  QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717

Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
             ++          +  I ++      I   ++I    I + Q  I   K   +  +    
Sbjct: 718  RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
             N           +  +V   +  + PT+ +    +       + L C+  G+P P++ W
Sbjct: 775  ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826

Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569
             +    L T    + T                   + CIA N +G+     T  V G+  
Sbjct: 827  QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
              +  +  E+  Q  +  D  L   V+ G P P ++W K+   +E      I  +   S+
Sbjct: 887  PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676
            +R++        KYT  A + AG S++ + +++  KP    KPEG ++ +
Sbjct: 943  LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%)

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
            I+   LSD G E +              ++  G+ P   ++P+ Q V +G  + L C   
Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716
             +P+P I W +K  E++ +  +    E+      SV+  +++   Q G YT  A N    
Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397

Query: 717  GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
             E  + +++ I      PP+V+    ++     ++V LS    G P P I+W +++    
Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451

Query: 777  ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
                K    G T +I  + P    D+G Y   A++  G    +  + V +P++  A
Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 60/267 (22%), Positives = 111/267 (41%), Gaps = 25/267 (9%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P FI + +  T      ++L       P P+ITW ++ ++I  S+     F+     L +
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKV 4624

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
            T ++S  DSG+Y C+A NS G S+  A + +D   +   K    S +         E   
Sbjct: 4625 T-LNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQ 4681

Query: 953  SHTVSTKWYHN----KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST 1008
            +++    W +N     K ++G+     +  G             D+ +  C V+++   +
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHS 4738

Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKY 1063
               +    E +PE ++ +   EV   D  +L+ E+ S+  T  VVW ++ + +      Y
Sbjct: 4739 IPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
                      L + N   +DEG Y C+
Sbjct: 4798 VLPN----NSLVLLNVEKYDEGVYKCV 4820



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  KPK      G+ + L C     P P I W   G+ ++ D    +A         S
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             LK+T       G YT +A N  G +++   + +       P+     K++      +VI
Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674

Query: 754  LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810
               +        +TW  N  P+ K L      +  S+ IL    +K  D  +YT K  N 
Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869
               +        E   E        +    ++ V    ++ L   VT +P+ + + W +N
Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ++ +   + I   +   N  LV+ NV+ + D G YKCVASNS GK+    ++ +
Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
            PQ I   K+     G  V L     G P PTITW K+ K ++    +       +T+   
Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
                D G YT  A+NS G +  SA I V+       +P         IT  E+   +  +
Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            R        +TW   N +  P      +F   N  LVI +  S +  GD +        +
Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734

Query: 915  SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972
              H    +T   E V  VK + K  E   G +V+L+C+ TS  ++T     K +   +D 
Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793

Query: 973  REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             + I                D GV KC+  +
Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%)

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
            TI ++   DAG Y+ R+ +N G+  V+  V   + P     P I  + + S+ +   E  
Sbjct: 485  TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464
                ST     VE +   T    +V N   T+ +  N      +  RA A V E    +A
Sbjct: 538  FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
               +   + ++   ++ P+V+   +++     E + L+C   G P+P+V WY  G+ L  
Sbjct: 596  GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653

Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
                   ++                Y+C A +  G+   +  + +   P + I    I+ 
Sbjct: 654  DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709

Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            K  VG    V+     I G P P++ W+KNG  L    +Y    K     + I   K   
Sbjct: 710  KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            +  Y+    N AG       L V   P+  E P  +R      VT++
Sbjct: 767  AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            TV   C   G P P I+W R + I I+ ++ +Q+        TL IR V P+D G + C+
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG-----TTLAIRNVLPDDDGFYHCI 4480

Query: 585  AKNAAGFASSTTELIVEAP 603
            AK+ AG   +T +LIV  P
Sbjct: 4481 AKSDAGQKIATRKLIVNKP 4499



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            Y C   N  G+ E +  + + + PV      +  QK    +  ++   + G P P VIW 
Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             +GN +  DK +     E  S++RI++L    S++ +  A N AGT+S +  ++    P+
Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827

Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             K EG      I RES TI    P+  G  ++T
Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 519  KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            K   +G     EC VEGYP PQ++W R    ++       Y  D  + T++  E    D+
Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110

Query: 579  GTFTCVAKNAAGFASS--TTELIV 600
            G + C A N AG A    T E++V
Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 510  PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            PI +   +  +T   G  V+ +C VE  P   +TWFR+   I    D + Y  + +  TL
Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            VI+    EDA  +TC A N AG A +  ++ V A
Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            E+ T  E S  P  V         +G      C+V G P P + W +     +P     +
Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             +    ++ L +RE    D GT+TC+A N AG + +TT++ V  P
Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            Y C A N  G       + +   P I +     +  HK GD+  +     G+P P + WY
Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            K+   L N       T +K SVI    +  S +  YT +A N   ++  ++ L V   P
Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T+    +AP  +E+ R +    G  V   C+  G P+P ITW++   ++  +   +    
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
                 +++   + P  AG +TC A+N         +LIV  P
Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP F+ K +      G+ V+  C   G P P ITW +   +I+ S+ F++ Y       L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAYSH-----L 4622

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             +      D+G +TC+A+N+ G  SST    +
Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
           V   C+  G P+P++ W+ +   +     +Q+  D      L IR+    D GT+ C A 
Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684

Query: 587 NAAGFASSTTELIVEAP 603
           + AG A  TT+L++  P
Sbjct: 685 SQAGQARDTTDLMLATP 701



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%)

Query: 508  MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            +AP F E   +R      G+     C  +G P P ITW +    I+P+ D  +++D    
Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600
              L I +    D G +TC+A N+ G     +T E+I+
Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            + VF KPT E        VE         G + + EC+++G+P+P I+W      +K  +
Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338

Query: 555  DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590
             F M    DN+       TL+I +    D G +TCVA N+ G
Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
            + KP KN T      +EL C   G P P +TW +DGK ++ +K                 
Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567
                Y C+A N  G    S  + +
Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T  E  + P   ++ R     +G+T    CQV G P P +TW R     K  + F     
Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
                  L IR     D G ++C+A N AG A
Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%)

Query: 522  PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            P   ++  +C  +G P PQ+ W    TA+   +    +  D   +    I  V   D G 
Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021

Query: 581  FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613
            +TC A+N AG  +    + +V+AP+  +G    V
Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%)

Query: 408  FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467
            FE     V  R GDT+    +  AE+   ++ V     +  D S Q+     K+   EK 
Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817

Query: 468  WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523
                   +D+  +   T   +  + +K  KL V E P   ++Q + PI +          
Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +  +C   G P P I + +    +  S +  +       +TLVI     E  G +TC
Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922

Query: 584  VAKNAAGFASSTTELIVEAPL 604
            +A+N AG   S  +++VE  L
Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 10/106 (9%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDM 688
            EG+P    K      V+ G  ++L+C + + P    + W    ++++ D+ I V   +  
Sbjct: 4747 EGVPEV--KTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPNNS- 4803

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734
                  L + NV+K+ EG Y  VA N  G+A     L +  G+  P
Sbjct: 4804 ------LVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 4843


>UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus
            musculus (Mouse)
          Length = 8891

 Score =  212 bits (518), Expect = 8e-53
 Identities = 272/1154 (23%), Positives = 473/1154 (40%), Gaps = 100/1154 (8%)

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFAS-----STTELIVEAPLSDHGSEMTVXXXXXXXX 621
            +LVI      D G + C A +A   AS      T  LI    L++   E+          
Sbjct: 2653 SLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESR 2712

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                   ++ +P T  +  + +   E    +LEC+ V+     + W   G E+       
Sbjct: 2713 AHLR---VKELPVTLLRPLRDKIAMEKHRGVLECQ-VSRASAQVRWFKGGVELQSGPKYE 2768

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            V  +    +Y  ++ I +V+   E TYT  A N +  A   +       E++   ++  L
Sbjct: 2769 VVSDG---LYRKLV-INDVQPEDEDTYTCDAGNVKTSAQFFV-------EEQSITIVRGL 2817

Query: 742  KSMIVRQGESVILSAQV-VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKV 797
            K M V +        +  + + RP   W      ++A   +  + DG  H +T+ K    
Sbjct: 2818 KDMTVMEPAPAWFECETSIPSVRPP-KWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCST 2876

Query: 798  KDEGV-YTL-KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
                V +T+ K+ +S  +  +   + +  P E  A   L     Q +          V  
Sbjct: 2877 MTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGREL-----QSV----------VLS 2921

Query: 856  VTRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
                P P ++ WY+++  +SPSE      +G+  EL I  + +  D+G Y+C     AG 
Sbjct: 2922 CDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRL-TPADAGVYRC----QAGS 2976

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973
            +   A VT++  +VT ++ LQ +   EEG+ V   C+ SH     +W  N   +      
Sbjct: 2977 AQSSAEVTVEAREVTVIQPLQDAEAMEEGR-VCFSCELSHKDEDIEWSLNGTPLYNDSFH 3035

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
            EI  EG             D G +         S  LVVK     F++ L D   +E+  
Sbjct: 3036 EISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGT 3095

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
              L+ E++   A VVW +DG  + P  +KYDF  +   R L + + S  D G Y+C +  
Sbjct: 3096 LTLQCEVSDPEARVVWRKDGVELGPS-DKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGS 3154

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSN 1150
            +   ++V+V +L   I  RL+  +V +G   +FE  L+     D  V W   G  +  S 
Sbjct: 3155 KETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAV-WTVGGKTVGGSG 3213

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            H      G+K  L + D  L DAGE    V      A L + E  ++ T  L E      
Sbjct: 3214 HFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPL-EDQRTTL 3272

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              D  L+ E+      V W K    I  ++K+ L+S+  +  L++RK +  D  EYTC  
Sbjct: 3273 GEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCET 3332

Query: 1271 LDAKSTTKLKVE--VVEFPPKIVDYEREYRIKRGSDV-TLLVDYQAFPQPNDEWIVNSKI 1327
              +KST KL VE     F  ++ D + E   ++G  V T   ++ A      + ++  + 
Sbjct: 3333 EASKSTAKLCVEEKANRFTEELADLQVE---EKGRAVFTCKTEHPASVVTWRKGLLELRA 3389

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
                KH  PS +  +  LTI  +E TD+  Y   +      A + ++   + +     + 
Sbjct: 3390 --SGKHV-PSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKV-RVIEDLED 3445

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
              ++  SS+   C   P + G    +++ ++   + + E   +  IT  Q    ++ T  
Sbjct: 3446 TAVQEGSSAKFCCRIAPADYGP---VHWFLDKTPLHSNE---LNEIT-VQPGGYHVLTLR 3498

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
                +       +  D   T+   +V ++  I S    +PL ++T    ED+ L C    
Sbjct: 3499 QLALKDSGTVYFEAGD-QRTSAALRVTEKPSIFS----RPLTDVTVTEGEDLTLVCETTT 3553

Query: 1508 VPQPKVTWYRDGKKLKTA---KATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
            V    V W +DGK L+ +   + ++E  +               YKC    + G   +S 
Sbjct: 3554 VDS-SVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKC----EIGGASSSS 3608

Query: 1564 VVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
            +V +   PV    S +D++     G    +  V+  +  P V W    + L++  +Y++ 
Sbjct: 3609 IVRVHALPVRFRESLKDVEVPE--GKAATLRCVLSSVAAP-VEWRHGDDVLKSSNKYSLR 3665

Query: 1623 TKEKTSVIRIKELKRSHSSKY-------TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
             +     + I++L+   S +Y       T  A+ T  TSS +   K+ +K +     V +
Sbjct: 3666 QEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTL 3725

Query: 1676 R-EISRESVTIEWK 1688
            R E+++E+  +EWK
Sbjct: 3726 RCELTKEA-PVEWK 3738



 Score =  205 bits (501), Expect = 9e-51
 Identities = 212/908 (23%), Positives = 373/908 (41%), Gaps = 67/908 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++ +PP F +  ++Q   EG+   L C++  A P   + W  KG E + D     ++  D
Sbjct: 4301 VKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLRDGG-RYSLRQD 4355

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
              + C  L+I ++     G Y+ V     G+     VL +   +  PP+  E LK     
Sbjct: 4356 GAV-CE-LQIHDLDVEDAGQYSCVC----GQEKTSAVLTV---DALPPKFTEGLKKEEAT 4406

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G  V L  Q+  +   T+ W K  K +        + DG    + I     V+D G Y+
Sbjct: 4407 EGTMVTLRCQM--SKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICG-LAVEDAGEYS 4463

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFIN--RFQEITVKEKGTIKLVARVTRNPVP 862
                   G  +TSA ++V+      A PP FI   R QE T   +GT+  + R   +   
Sbjct: 4464 CVC----GQEKTSATLSVK------ALPPRFIEDLRSQEAT---EGTMATL-RCQMSKAA 4509

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             + W + +E +   +  +   DG   EL I ++  E D+G+Y CV     G+    A ++
Sbjct: 4510 PVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVE-DAGEYLCVC----GQEKTSATLS 4564

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
            +      F++ L +S E  EG    L CQ S     +W    K +   D   + Q+G   
Sbjct: 4565 VKALPPRFIEDL-RSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMC 4623

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C+   ++TS  L VK   P FI  L+  E +E  VA L   + S
Sbjct: 4624 ELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRM-S 4682

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            + A V W +  E +K   ++Y   + G++ +L IR+ +V D  EYSC+   E  +A ++V
Sbjct: 4683 KAAPVEWRKGSETLKDG-DRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSV 4741

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
              LP + I  L++Q+  + +  T   +L+K  ++V W K    ++      L  DG   +
Sbjct: 4742 KALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVV-WKKGSETLRNGARYSLRQDGAVCE 4800

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            L+I D  ++D GEYSC  G  + +A L++  P + F   L   +     + A L  E+  
Sbjct: 4801 LEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQN-LQAEEGSMASLRCELSV 4859

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
                + W K    ++   +           L++R    +D  EY+C       TT   + 
Sbjct: 4860 PNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTC--GSQTTSATLM 4917

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            V   P + +   +   +  G+   L  +       + EW   S  +  C   +   +  +
Sbjct: 4918 VTAAPVRFLRELQAQDVDEGATARLRCELSR-EAVSVEWRKGSLQLFPCAKYQMVQEGTT 4976

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            A L +  VE  DAG Y      + GH      +++   P P  K ++             
Sbjct: 4977 AELLVHGVEQEDAGEYTC----DAGHTQSIARLSV-RAPKPKFKTDLQS----------T 5021

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            E E  G + +   + E +     +W+         +  +  +  +      + +   D  
Sbjct: 5022 EQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTG 5081

Query: 1463 DASETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            + +      K +   +++ P  T+ + L ++  + +ED+E TC         V W+  G 
Sbjct: 5082 EYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGL 5141

Query: 1521 KLKTAKAT 1528
             L++ + T
Sbjct: 5142 PLQSNEVT 5149



 Score =  194 bits (472), Expect = 3e-47
 Identities = 186/734 (25%), Positives = 302/734 (41%), Gaps = 64/734 (8%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +  +P  F    K +   EG+   L C L  A P   + W  KG + +   +  V  +  
Sbjct: 3877 VRALPAKFKDSLKNEEATEGTTATLSCELSKAAP---VTWK-KGPKTLQSGDKYVLRQDG 3932

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                C  L+I  +     G Y+ V    +  A+L +          P + IE L+S    
Sbjct: 3933 A--VCG-LQIHGLTMADAGEYSCVCGQEKTSATLTV-------RGLPAKFIEDLRSQEAT 3982

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G + IL  ++  +    + W K ++ +K       + DG    + I +   V D G Y+
Sbjct: 3983 EGATAILRCEL--SKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQI-RGLAVVDTGTYS 4039

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            L  + +EG+         EE TE                    GT+  + R   +    +
Sbjct: 4040 LPTKFTEGLRN-------EEATE--------------------GTMATL-RCQMSKAAPV 4071

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W + +E +   +  +   DG   EL I  +  E DSG+Y CV     G+    A +++ 
Sbjct: 4072 EWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIE-DSGEYTCVC----GQEKTSATLSVK 4126

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
                 F++ L +S E  EG    L CQ S T   +W    + +       + Q+G     
Sbjct: 4127 ALPSRFIEDL-RSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCEL 4185

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G   C+   ++TS  L +K   P FI  L+  E  E  +A L  ++ S+ 
Sbjct: 4186 QICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQM-SKA 4244

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A V W +  E +     +Y   + G + +L I + +V D GEYSC+   E  +A + V  
Sbjct: 4245 APVEWRKGSETLGDG-GRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKA 4303

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            LPP  I  L++Q+  +G  AT   +++K  A V W K    ++      L  DG   +L+
Sbjct: 4304 LPPRFIEDLRSQEATEGTMATLRCQMSKA-APVEWRKGSETLRDGGRYSLRQDGAVCELQ 4362

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I+D D++DAG+YSC  G  K +A+LTV+     FT  L +       T   L  ++  E 
Sbjct: 4363 IHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKK-EEATEGTMVTLRCQMSKEA 4421

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
              V W K    + D  +++L  D     L I     +D  EY+CV    K++  L V+ +
Sbjct: 4422 -TVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKAL 4480

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
              PP+ ++  R      G+  TL    Q       EW   S+ ++         D     
Sbjct: 4481 --PPRFIEDLRSQEATEGTMATLRC--QMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCE 4536

Query: 1345 LTIKKVENTDAGIY 1358
            L I+ +   DAG Y
Sbjct: 4537 LQIRDLAVEDAGEY 4550



 Score =  185 bits (450), Expect = 1e-44
 Identities = 168/659 (25%), Positives = 288/659 (43%), Gaps = 48/659 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++ +PP F +  ++Q   EG+   L C++  A P   + W  KG E + D     ++  +
Sbjct: 4213 IKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLGDGG-RYSLRQN 4267

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                C  L+I ++     G Y+ V     G+      L +K     PP+ IE L+S    
Sbjct: 4268 -GAVCE-LQIHDLAVEDTGEYSCVC----GQEKTSATLNVKA---LPPRFIEDLRSQEAT 4318

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G    L  Q+  +    + W K ++ ++       + DG    + I     V+D G Y+
Sbjct: 4319 EGTMATLRCQM--SKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQI-HDLDVEDAGQYS 4375

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
                   G  +TSAV+TV+      A PP F    ++    E GT+ +  R   +   ++
Sbjct: 4376 CVC----GQEKTSAVLTVD------ALPPKFTEGLKKEEATE-GTM-VTLRCQMSKEATV 4423

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W +  + +S     +   DG   EL I  +  E D+G+Y CV     G+    A +++ 
Sbjct: 4424 EWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVE-DAGEYSCV----CGQEKTSATLSVK 4478

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
                 F++ L +S E  EG    L CQ S     +W    + +   D   + Q+G     
Sbjct: 4479 ALPPRFIEDL-RSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCEL 4537

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G   C+   ++TS  L VK   P FI  L+  E  E  +A L  ++ S+ 
Sbjct: 4538 QIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQM-SKA 4596

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A V W +  + ++   ++Y   + G + +L I + +V D G+YSC+   E  +A ++V  
Sbjct: 4597 APVEWRKGSKTLR-DGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKA 4655

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            LPP  I  L++Q+  +G  AT    ++K  A V W K    ++  +   L  +G   +L+
Sbjct: 4656 LPPRFIEDLRSQEAREGTVATLRCRMSKA-APVEWRKGSETLKDGDRYSLRQEGNLCELQ 4714

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPD 1222
            I D  ++D  EYSC  G  K +A L+V+     F   LR  E    P ++   L  ++  
Sbjct: 4715 IRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQE---APESSTVTLRCKL-S 4770

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
            +   V W K    + +  +++L  D     L IR  T +D  EY+C     +++  L +
Sbjct: 4771 KKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSI 4829



 Score =  182 bits (442), Expect = 1e-43
 Identities = 163/640 (25%), Positives = 268/640 (41%), Gaps = 38/640 (5%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V EGS     CR+       + W      +  +E   + ++   +    VL +  +    
Sbjct: 3448 VQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGY---HVLTLRQLALKD 3504

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             GT    A ++   A+L +  K       P     PL  + V +GE + L  +       
Sbjct: 3505 SGTVYFEAGDQRTSAALRVTEK-------PSIFSRPLTDVTVTEGEDLTLVCETT-TVDS 3556

Query: 765  TITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++ W K+ K ++  A    S     +  ++     +D G Y  +     G A +S+++ V
Sbjct: 3557 SVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEI----GGASSSSIVRV 3612

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
                  +A P  F    +++ V E G    +  V  +    + W   ++++  S   +  
Sbjct: 3613 ------HALPVRFRESLKDVEVPE-GKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLR 3665

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             +G  +ELVI ++  + DSG Y C    S G  +  A +T+      FV  L+   E  E
Sbjct: 3666 QEGAVLELVIRDLQPQ-DSGQYSC----SFGDQTTSATLTVKTSSAQFVGKLRNK-EATE 3719

Query: 943  GKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            G TV L C+ +     +W    + +   D   + Q+G             D G   C+  
Sbjct: 3720 GTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCG 3779

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062
             ++TS  L VK  +  F+R+L+  E  E D   L+ E+ S+ A V W +  E ++   ++
Sbjct: 3780 QEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCEL-SKAAPVEWRKGTETLRDG-DR 3837

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122
            Y  ++ G + +L IR+ ++ D GEY C    E  +A +TV  LP +    L+N++  +G 
Sbjct: 3838 YSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGT 3897

Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
             AT   EL+K  A V W K    +Q  +   L  DG    L+I+   + DAGEYSC  G 
Sbjct: 3898 TATLSCELSKA-APVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQ 3956

Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242
             K +A LTV      F   L         T A L  E+  +   V W K    ++D +++
Sbjct: 3957 EKTSATLTVRGLPAKFIEDLRSQEATEGAT-AILRCEL-SKAAPVEWRKGSETLKDGDRY 4014

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            TL  D     L IR     D   Y+   L  K T  L+ E
Sbjct: 4015 TLRQDGAVCELQIRGLAVVDTGTYS---LPTKFTEGLRNE 4051



 Score =  178 bits (433), Expect = 2e-42
 Identities = 199/929 (21%), Positives = 362/929 (38%), Gaps = 71/929 (7%)

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G S  LS +V    +  +TW K+ K + +   +  ++ G +  + + +  K  D G Y+ 
Sbjct: 878  GNSATLSCEVT-QAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA-DAGEYSC 935

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            +A    G  + S  + V EP    A+         E+  +   +  L   V +     +T
Sbjct: 936  EA----GGQKLSFRLDVAEPKLVFAKGQ---QAHSEVKAEAGASATLSCEVAQAQT-EVT 987

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W+++ + +S S  +     G +  LV+     + D+G+Y C     AG      R+ +  
Sbjct: 988  WFKDGKKLSSSSKVRMEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFRLDVAE 1042

Query: 926  EKVTFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982
             K+ F K  Q   E   E G +  L C+ +       W+ + K++S      +   G   
Sbjct: 1043 PKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSR 1102

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD-FEVKEK--DVAILEVE 1039
                      D G   C    Q+ S  L V E    F ++ Q   EVK +  + A L  E
Sbjct: 1103 RLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCE 1162

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            +     +V W +DG+ +    +K   E  G  R+L ++     D GEYSC    +  +  
Sbjct: 1163 VAQAQTEVTWFKDGKKLS-SSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFR 1221

Query: 1100 VTVVELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
            + V E  P+++   + Q     K   GN AT   E+ +    V WFKDG ++  S+ +++
Sbjct: 1222 LDVAE--PKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRM 1279

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANT 1212
               G  ++L +      DAGEYSCE G  K +  L V EP + F    +    +   A  
Sbjct: 1280 EASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGA 1339

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             A L+ E+     +VTW+K    +  + K  + +    R L++++  + D  EY+C    
Sbjct: 1340 SATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEG 1399

Query: 1273 AKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
             K + +L V   +    K      E + + G+  TL  +  A  Q    W  + K +   
Sbjct: 1400 QKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSS 1458

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
               +      S  L +++    DAG Y        G   +   + +        +P ++ 
Sbjct: 1459 SKVRVEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDV-------AEPKLVF 1507

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
                  N   +     G S  +   V   + + T W        + + ++   +  S R 
Sbjct: 1508 AKEQQANS--EVKAEAGASATLSCEVAQAQTEVT-WFKDGKKLSSSSKVRVEASGCSRRL 1564

Query: 1452 RAYAVNEVDISDAS-----ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
                  + D  + S     +   +   + E K+     ++    +  E      L+C   
Sbjct: 1565 VVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVA 1624

Query: 1507 GVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
               Q +VTW++DGKKL  ++K   E                    Y C A    G  + S
Sbjct: 1625 QA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLS 1679

Query: 1563 CVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIE---GIPPPEVIWYKNGNKLENDKE 1618
              + + + P +  + E  +Q H +V  E   +A +         EV W+K+G KL +  +
Sbjct: 1680 FRLDVAE-PKLAFAKE--QQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSK 1736

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
              +     +  + +++  ++ + +Y+ EA
Sbjct: 1737 VRVEASGCSRRLVVQQAGKADAGEYSCEA 1765



 Score =  177 bits (430), Expect = 4e-42
 Identities = 223/1046 (21%), Positives = 412/1046 (39%), Gaps = 85/1046 (8%)

Query: 636  FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            F+K+ +A+     + G+   L C  VA  + ++ W   G+++     + +         C
Sbjct: 1047 FAKEQQARSEVKAEAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRMEASG-----C 1100

Query: 693  SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S  L +    K   G Y+  A  ++    L +        KE  Q    +K+ +   G S
Sbjct: 1101 SRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQ-QARSEVKAEV---GNS 1156

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
              LS +V    +  +TW K+ K + +   +  ++ G +  + + +  K  D G Y+ +A 
Sbjct: 1157 ATLSCEVA-QAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA-DAGEYSCEA- 1213

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
               G  + S  + V EP    A+         E+  +   +  L   V +     +TW++
Sbjct: 1214 ---GGQKLSFRLDVAEPKLVFAKEQ---QARSEVKAEAGNSATLSCEVAQAQT-EVTWFK 1266

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            + + +S S  +     G +  LV+     + D+G+Y C     AG       + +   K+
Sbjct: 1267 DGKKLSSSSKVRMEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFHLDVTEPKL 1321

Query: 929  TFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             F K  Q   E   E G +  L C+ +       W+ + K++S      +   G      
Sbjct: 1322 VFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLV 1381

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD-FEVKEKD--VAILEVEINS 1042
                   D G   C  + Q+ S  L V E    F ++ Q   EVK +    A L  E+  
Sbjct: 1382 VQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQ 1441

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
               +V W +DG+ +    +K   E  G  R+L ++     D GEYSC    +  +  + V
Sbjct: 1442 AQTEVTWFKDGKKLS-SSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDV 1500

Query: 1103 VELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157
             E  P+++   + Q     K   G  AT   E+ +    V WFKDG ++  S+ +++   
Sbjct: 1501 AE--PKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEAS 1558

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAY 1215
            G  ++L +      DAGEYSCE G  K +  L V EP + F    +    +   A   A 
Sbjct: 1559 GCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASAT 1618

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            L+ E+     +VTW+K    +  + K  + +    R L++++  + D  EY+C     K 
Sbjct: 1619 LSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKL 1678

Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            + +L V   +    K      E + + G+  TL  +  A  Q    W  + K +      
Sbjct: 1679 SFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSSSKV 1737

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            +      S  L +++    DAG Y      +C     +++   LD   P  K    +   
Sbjct: 1738 RVEASGCSRRLVVQQAGKADAGEY------SCEAGGQKLSFR-LDVAEP--KLAFAKEQQ 1788

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            +   +   + E   ++T+   V + Q    TE    K+  K  +S   ++  +S   R  
Sbjct: 1789 AHSEV---KAEAGASATLSCEVAQAQ----TEVTWFKDGKKLSSS-SKVRVEASGCSRRL 1840

Query: 1455 AVNEVDISDASETT-------EYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
             V +   +DA E +        ++++ + E K+     ++    +  E      L+C   
Sbjct: 1841 VVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVA 1900

Query: 1507 GVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
               Q +VTW++DGKKL  ++K   E                    Y C A    G  + S
Sbjct: 1901 QA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLS 1955

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNI 1621
              + + +  ++    +    + K       T   E      EV W+K+G KL +  +  +
Sbjct: 1956 FRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRV 2015

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEA 1647
                 +  + ++++ ++ + +Y+ EA
Sbjct: 2016 EASGCSRRLVVQQVGKADAGEYSCEA 2041



 Score =  169 bits (410), Expect = 1e-39
 Identities = 230/1078 (21%), Positives = 408/1078 (37%), Gaps = 78/1078 (7%)

Query: 636  FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            F+K+ +A+     + G+   L C  VA  + ++ W   G+++     + V         C
Sbjct: 1415 FAKEQQARSEVKAEAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----C 1468

Query: 693  SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S  L +    K   G Y+  A  ++    L +        KE  Q    +K+     G S
Sbjct: 1469 SRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQ-QANSEVKA---EAGAS 1524

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
              LS +V    +  +TW K+ K + +   +  ++ G +  + + +  K  D G Y+ +A 
Sbjct: 1525 ATLSCEVA-QAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA- 1581

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
               G  + S  + V EP    A+         E+  +   +  L   V +     +TW++
Sbjct: 1582 ---GGQKLSFRLDVAEPKLAFAKEQ---QAHSEVKAEAGASATLSCEVAQAQT-EVTWFK 1634

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            + + +S S  +     G +  LV+     + D+G+Y C     AG      R+ +   K+
Sbjct: 1635 DGKKLSSSSKVRVEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFRLDVAEPKL 1689

Query: 929  TFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             F K  Q   E   E G +  L C+ +       W+ + K++S      +   G      
Sbjct: 1690 AFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLV 1749

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD--VAILEVEINS 1042
                   D G   C    Q+ S  L V E    F ++ Q   EVK +    A L  E+  
Sbjct: 1750 VQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQ 1809

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
               +V W +DG+ +    +K   E  G  R+L ++     D GEYSC    +     + V
Sbjct: 1810 AQTEVTWFKDGKKLS-SSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDV 1868

Query: 1103 VELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157
             E  P+++   + Q     K   G  AT   E+ +    V WFKDG ++  S+ +++   
Sbjct: 1869 AE--PKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEAS 1926

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAY 1215
            G  ++L +      DAGEYSCE G  K +  L V EP + F    +    +   A   A 
Sbjct: 1927 GCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASAT 1986

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            L+ E+     +VTW+K    +  + K  + +    R L++++  + D  EY+C     K 
Sbjct: 1987 LSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKL 2046

Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            + +L V        K      E + + G+  TL  +  A  Q    W  + K +      
Sbjct: 2047 SFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEV-AQAQTEVTWFKDGKKLSSSSKV 2105

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            +      S  L +++    DAG Y        G   +   + + +  S      I E  S
Sbjct: 2106 RVEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEAES-----QIPERPS 2156

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFR 1452
                +   E E    + I+   +    +    W+   V+     +    +L    +   R
Sbjct: 2157 RREPLVVKEHE----TIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVR 2212

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
               V +  I       E      + +  +    KPL+ +  E    + L C      Q +
Sbjct: 2213 GAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCEL-SPEQAE 2271

Query: 1513 VTWYRDGKKLKTAK---ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            V W     +L+  K    T E  R               Y C + +D     TS  + ++
Sbjct: 2272 VVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD----RTSARLTVK 2327

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
               V+  ++       + G E     V+       V WYK+G +L+  +++ +     + 
Sbjct: 2328 VPRVVKFTSGLSAMVAEEGQEATFQCVVSP-SDAGVTWYKDGMQLQPSEKFVMVESGASR 2386

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             + I  L    + + T+EA   + ++++ V         K E P  + E  R SVT+E
Sbjct: 2387 SLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLE-PQTVEE--RTSVTLE 2441



 Score =  168 bits (409), Expect = 1e-39
 Identities = 170/736 (23%), Positives = 310/736 (42%), Gaps = 47/736 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++ +PP F +  ++Q   EG+   L C++  A P   + W  KG E + D +   ++  D
Sbjct: 4477 VKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLRDGD-RYSLRQD 4531

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
              + C  L+I ++     G Y  V    +  A+L +       +  PP+ IE L+S    
Sbjct: 4532 GAV-CE-LQIRDLAVEDAGEYLCVCGQEKTSATLSV-------KALPPRFIEDLRSQEAT 4582

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G    L  Q+  +    + W K +K ++       + DG    + I     V+D G Y+
Sbjct: 4583 EGTMATLRCQM--SKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICD-LAVEDTGDYS 4639

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
                   G  +TSA ++V+      A PP FI   +    +E GT+  + R   +    +
Sbjct: 4640 CVC----GQEKTSATLSVK------ALPPRFIEDLRSQEARE-GTVATL-RCRMSKAAPV 4687

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W + +E +   +  +   +G   EL I ++  E D+ +Y CV     G+    A +++ 
Sbjct: 4688 EWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVE-DTEEYSCVC----GQEKTSATLSVK 4742

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
                 F++ L +S E  E  TV L C+ S   S  W    + +       + Q+G     
Sbjct: 4743 ALPAKFIEDL-RSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCEL 4801

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G   C    + TS  L +      F + LQ+ + +E  +A L  E++   
Sbjct: 4802 EIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPN 4861

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A +VW + G  ++    + +  ++G + +L +R+    D GEYSC    ++ +A + V  
Sbjct: 4862 AAMVWSKGGLELQGDTRR-EARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTA 4920

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
             P   +  LQ Q V++G  A    EL++    V W K   ++      Q+  +G   +L 
Sbjct: 4921 APVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELL 4980

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            ++  + +DAGEY+C+ G+++  A L+V  P   F   L +     A   A L  ++ +  
Sbjct: 4981 VHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDL-QSTEQEAGGTARLCCQLSEAE 5039

Query: 1225 --LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
                V W K+   +    K+ +        L+I      D  EY C++   K+   L+V+
Sbjct: 5040 PGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVK 5099

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DS 1340
              E    IV    +  ++   DV            + +W +    ++  + T+ ++  D 
Sbjct: 5100 EPEV--TIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADG 5157

Query: 1341 KSASLTIKKVENTDAG 1356
             +  L +K V   DAG
Sbjct: 5158 CTHVLQLKGVTLEDAG 5173



 Score =  167 bits (405), Expect = 4e-39
 Identities = 179/754 (23%), Positives = 300/754 (39%), Gaps = 50/754 (6%)

Query: 637  SKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            +K+ K   V EG     EC L    P     W   G+ +    +     +     Y   +
Sbjct: 3171 TKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQG--RKYTLTV 3228

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            K   +    E  ++V+ +    +ASL I        + P  + +PL+      GE V+LS
Sbjct: 3229 KDAALSDAGEVVFSVLGLT--SKASLII-------RERPVDITKPLEDQRTTLGEDVMLS 3279

Query: 756  AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             ++      ++ W K+ K ++        S+G T ++ +++   +KD G YT + E S+ 
Sbjct: 3280 CEL-SRAGTSVRWLKDGKAIRKSQKYDLLSEG-TRAVLVVRKASLKDSGEYTCETEASKS 3337

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
             A+    + VEE          F     ++ V+EKG      + T +P   +TW +    
Sbjct: 3338 TAK----LCVEEKANR------FTEELADLQVEEKGRAVFTCK-TEHPASVVTWRKGLLE 3386

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +  S     + +G  ++L I N     DS  Y C      G++   AR+ +  +KV  ++
Sbjct: 3387 LRASGKHVPSQEGLTLKLTI-NALERTDSDTYTC----DIGQARTQARLLVHGQKVRVIE 3441

Query: 933  HLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREI-IQEGRXXXXXXXXX 989
             L+ +   +EG +    C+ +        W+ +K  +   +  EI +Q G          
Sbjct: 3442 DLEDT-AVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQL 3500

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
               D G +     DQ TS  L V E    F R L D  V E +   L  E  +  + V W
Sbjct: 3501 ALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRW 3560

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             +DG+ ++P   +      G   +L I  T+  D G Y C +   S ++ V V  LP   
Sbjct: 3561 TKDGKTLRPSA-RCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRF 3619

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
               L++ +V +G  AT    L+   A V W      ++ SN   L  +G   +L I D  
Sbjct: 3620 RESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQ 3679

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
              D+G+YSC  G+   +A LTV+  S  F  +L         T   L  E+  E   V W
Sbjct: 3680 PQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTT-VTLRCELTKEA-PVEW 3737

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
             K    + + +K++L  D     L I      D  EY+CV    K++  L V+ +     
Sbjct: 3738 KKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKAL----- 3792

Query: 1290 IVDYEREYRIKRGSD-VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
            +V + R  R K  ++  T  +  +       EW   ++ ++         D     L I+
Sbjct: 3793 LVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIR 3852

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             +   DAG Y       CG       +T+   P+
Sbjct: 3853 SLTIADAGEYLC----TCGQEKTSATLTVRALPA 3882



 Score =  164 bits (398), Expect = 3e-38
 Identities = 143/655 (21%), Positives = 276/655 (42%), Gaps = 38/655 (5%)

Query: 636  FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            F+K+ +A+     + G+   L C  VA  + ++ W   G+++     + V         C
Sbjct: 2059 FAKEQQARTEVKAEAGNSATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----C 2112

Query: 693  SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S  L +    K   G Y+  A    G   L   L +   E + P+     + ++V++ E+
Sbjct: 2113 SRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAEAESQIPERPSRREPLVVKEHET 2168

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            +IL+A +       +TW K+   +   K     S GDTH++T+ +  +V D  +Y+ +  
Sbjct: 2169 IILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTV-RGAQVLDSAIYSCRV- 2226

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
              EG       + VEE   + ++P       + +  +  GT+ LV  ++      + W  
Sbjct: 2227 GKEG---QDFPVQVEEVAAKFSKP------LEPVEGELGGTVMLVCELSPEQA-EVVWRC 2276

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             N  + P +      +G    L ++ +  E D+ +Y C + +   ++S  AR+T+ V +V
Sbjct: 2277 GNTQLRPGKRFQMTSEGPRRTLTVSGL-REDDAEEYVCESRDD--RTS--ARLTVKVPRV 2331

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
                    +   EEG+    +C  S +     WY +  ++   +   +++ G        
Sbjct: 2332 VKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTIL 2391

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D G +    +   +S  L V+E    F +KL+   V+E+    LEVE+     +V
Sbjct: 2392 GLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEV 2451

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W R+  ++ P +N  +    G    L +R+    D G + C   D+   A++ V     
Sbjct: 2452 KWTRNAAVLTPSEN-VEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQV 2510

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
             ++  LQ  +  +   A+ ++EL+  +    W +DG  +Q      L + G    L +  
Sbjct: 2511 RLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSA 2570

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
                D+G  +        +A L V E  ++FT R+ + ++        L  E+    +DV
Sbjct: 2571 LQPQDSGLVAFRAEGVHTSARLIVTELPVSFT-RVLQDVVATQKEKVTLECEL-SRPVDV 2628

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             W K    +   +   +++    R+L+I +C   DQ  Y C  LDA+++  L+V+
Sbjct: 2629 RWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQ 2683



 Score =  149 bits (362), Expect = 6e-34
 Identities = 197/893 (22%), Positives = 344/893 (38%), Gaps = 60/893 (6%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704
            + G+   L C  VA  + ++ W   G+++     + V         CS  L +    K  
Sbjct: 1612 EAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----CSRRLVVQQAGKAD 1665

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y+  A  ++    L +  + K    +  Q    +K+     G S  LS +V    + 
Sbjct: 1666 AGEYSCEAGGQKLSFRLDVA-EPKLAFAKEQQAHSEVKA---EAGASATLSCEVA-QAQT 1720

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             +TW K+ K + +   +  ++ G +  + + +  K  D G Y+ +A    G  + S  + 
Sbjct: 1721 EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA----GGQKLSFRLD 1775

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V EP    A+         E+  +   +  L   V +     +TW+++ + +S S  +  
Sbjct: 1776 VAEPKLAFAKEQ---QAHSEVKAEAGASATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRV 1831

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET- 940
               G +  LV+     + D+G+Y C     AG      R+ +   K+ F K  Q   E  
Sbjct: 1832 EASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLFFRLDVAEPKLMFAKEQQAHSEVK 1886

Query: 941  -EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
             E G +  L C+ +       W+ + K++S      +   G             D G   
Sbjct: 1887 AEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYS 1946

Query: 999  CIVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD--VAILEVEINSETADVVWERDGEI 1055
            C    Q+ S  L V E    F ++ Q   EVK +    A L  E+     +V W +DG+ 
Sbjct: 1947 CEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKK 2006

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115
            +    +K   E  G  R+L ++     D GEYSC  R +  +  + V +         Q 
Sbjct: 2007 LS-SSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQA 2065

Query: 1116 Q---KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            +   K   GN AT   E+ +    V WFKDG ++  S+ +++   G  ++L +      D
Sbjct: 2066 RTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKAD 2125

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETL-DVTW 1229
            AGEYSCE G  K +  L V E       R    E ++V  +    LT  I   ++  VTW
Sbjct: 2126 AGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTW 2185

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
             K    I  +++    S     TL +R     D   Y+C +   K      V+V E   K
Sbjct: 2186 LKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRV--GKEGQDFPVQVEEVAAK 2243

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
                      + G  V L+ +     Q    W   +  ++  K  + + +    +LT+  
Sbjct: 2244 FSKPLEPVEGELGGTVMLVCELSP-EQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSG 2302

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
            +   DA  Y     ++   A + + V  + K +      + E    +   C   P + G 
Sbjct: 2303 LREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAG- 2361

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
              + +Y    Q   + +++ V++      +I  L    + +    A  E   S A+    
Sbjct: 2362 --VTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEA--EGASSSAALRVR 2417

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
               V+ + K++  TVE+      T    ++ELT      P P+V W R+   L
Sbjct: 2418 EAPVLFKKKLEPQTVEE-----RTSVTLEVELT-----RPWPEVKWTRNAAVL 2460



 Score =  135 bits (327), Expect = 1e-29
 Identities = 182/828 (21%), Positives = 322/828 (38%), Gaps = 95/828 (11%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            S AP F+ + +      G      CQ+ G P P ++W +    ++    F++  D D V 
Sbjct: 6    SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGD-VY 64

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
             L I ++   D+G + C A+NA G A +   L V+       SE T              
Sbjct: 65   RLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVD-------SEGTCAEQA--------- 108

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
                   P F  +P +  V EG+D    CR+   P+P ++W   G  + P +   V +E 
Sbjct: 109  -------PHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEE 161

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPP--------- 735
              H   S L+I + +    GTY V A N  G   A+  +V+        PP         
Sbjct: 162  --HGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLA 219

Query: 736  -----------QVIEP------LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--- 775
                       + I P       ++  V +G+   LS  V G P+P   W K+ + V   
Sbjct: 220  HLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEG 279

Query: 776  -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
             + +  + + +   + IL  K+  D G+YT  A N  G   +S ++ V EPT        
Sbjct: 280  RRHVVYEDEQENFVLKILFCKQ-SDRGLYTCTASNLVGQTYSSVLVVVREPTVP------ 332

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            F  R Q++ V+EK +      V + P     W++    +  S       +G    L + N
Sbjct: 333  FKKRLQDLEVREKESATFQCEVAQ-PATEAAWFKEETRLWASAKYDIEEEGTERRLTVRN 391

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTS 953
            V ++ D   Y C       +++ G+R   ++  +    + L +      G T I   + +
Sbjct: 392  VSAD-DDAVYIC-------ETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELA 443

Query: 954  HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012
                  +W  N++E+       I  EG             D+G +  +     T+T   V
Sbjct: 444  VPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCV 503

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKK-NKYDFEK--- 1067
                   +    D  VK K  + + +  ++    D     DG +++ +K   Y + +   
Sbjct: 504  SAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHE 563

Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE--------IITRLQNQKVN 1119
             G +       T V +EG++   +   +   +   +E P          + T L+  +  
Sbjct: 564  AGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAV 623

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            +G + TF ++LT   +   WF DG  ++ S+   +  D  +  L I +      G     
Sbjct: 624  EGGEVTFSVDLTVASS-GEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKF 682

Query: 1180 VGNSKCTAILTVEEPSINF-TLRLPEF----ILVPANTDAYLTVEIPDETLDVTWYKKKS 1234
            V N   T+I  V   ++   + +LP      +L   + +A L  E+ D+   VTW K   
Sbjct: 683  VANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGR 742

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             +    K+ +     +R L++R   +DD   Y CV   +++  +L V+
Sbjct: 743  ELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQ 790



 Score =  130 bits (315), Expect = 3e-28
 Identities = 161/721 (22%), Positives = 278/721 (38%), Gaps = 41/721 (5%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704
            + G+   L C  VA  + ++ W   G+++     + V         CS  L +  V K  
Sbjct: 1980 EAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----CSRRLVVQQVGKAD 2033

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y+  A  ++    L +        KE  Q    +K+     G S  LS +V    + 
Sbjct: 2034 AGEYSCEARGQKLSFRLDVADTRLMFAKEQ-QARTEVKA---EAGNSATLSCEVA-QAQT 2088

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             +TW K+ K + +   +  ++ G +  + + +  K  D G Y+ +A    G  + S  + 
Sbjct: 2089 EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA----GGQKLSFRLD 2143

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V E   +  E P   +R + + VKE  TI L A +    V ++TW ++   I  S+    
Sbjct: 2144 VAEAESQIPERP---SRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEA 2200

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
               G+   L +      +DS  Y C      GK      V ++     F K L+   E E
Sbjct: 2201 TSLGDTHTLTVRGAQV-LDSAIYSC----RVGKEGQDFPVQVEEVAAKFSKPLEP-VEGE 2254

Query: 942  EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
             G TV+L C+ S       W     ++      ++  EG             D     C 
Sbjct: 2255 LGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCE 2314

Query: 1001 VKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
             +D  TS  L VK   + +F   L     +E   A  +  ++   A V W +DG  ++P 
Sbjct: 2315 SRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPS 2374

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
            + K+   + G  R L I   ++ D G+ +      S +A + V E P     +L+ Q V 
Sbjct: 2375 E-KFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVE 2433

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            +    T E+ELT+    V+W ++ + +  S ++++  +G +  L +      D G + CE
Sbjct: 2434 ERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCE 2493

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
              + K  A L VE   +     L E       T A + VE+    ++ +W +    ++  
Sbjct: 2494 TPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGT-ASMDVELSHAEVEGSWTRDGLRLQPG 2552

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKIVDYEREYR 1298
             K  L        L +      D      V   A+   T  ++ V E P       ++  
Sbjct: 2553 PKCHLAVQGPVHILTLSALQPQDS---GLVAFRAEGVHTSARLIVTELPVSFTRVLQDVV 2609

Query: 1299 IKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
              +   VTL  +     +P D  W+ +   ++  K           SL I + E  D G+
Sbjct: 2610 ATQKEKVTLECE---LSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGV 2666

Query: 1358 Y 1358
            Y
Sbjct: 2667 Y 2667



 Score =  128 bits (310), Expect = 1e-27
 Identities = 192/880 (21%), Positives = 336/880 (38%), Gaps = 85/880 (9%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            +    L PK   +  +V   C     P+  + W++    + PS+ F+M  +   +A L I
Sbjct: 2902 VLTRPLEPKAGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMALEGQ-MAELRI 2959

Query: 571  REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630
              + P DAG + C     AG A S+ E+ VEA       E+TV                 
Sbjct: 2960 LRLTPADAGVYRC----QAGSAQSSAEVTVEA------REVTV----------------- 2992

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
             I P       A+ ++EG  +   C L +  + DI W   G  +  D    ++ E  +H 
Sbjct: 2993 -IQPL----QDAEAMEEGR-VCFSCEL-SHKDEDIEWSLNGTPLYNDSFHEISHEGCLH- 3044

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L + +V+  Q  T TV A + +   S  +V+K K     P   ++ L  +   +  
Sbjct: 3045 ---TLVLKSVR--QADTGTVCATSPKVSVSARLVVKGK-----PVVFLKALDDVSAEERG 3094

Query: 751  SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            ++ L  + V +P   + W K+     P              +T+      +D G+YT + 
Sbjct: 3095 TLTLQCE-VSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTV-HDLSHEDAGLYTCQV 3152

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITW 866
                G  ET + ++V +             R + + V E  +      ++  +P     W
Sbjct: 3153 ----GSKETQSKVSVHDLHVG------ITKRLKTVEVLEGESCSFECVLSHESPSDPAVW 3202

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
                + +  S        G    L + +  +  D+G+   V  +  G +S  A + I   
Sbjct: 3203 TVGGKTVGGSGHFHAVRQGRKYTLTVKDA-ALSDAGE---VVFSVLGLTSK-ASLIIRER 3257

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             V   K L+    T  G+ V+L C+ S    S +W  + K I      +++ EG      
Sbjct: 3258 PVDITKPLE-DQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLV 3316

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D G   C  +  +++  L V+E    F  +L D +V+EK  A+   +     +
Sbjct: 3317 VRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPAS 3376

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
             V W R G +      K+   + G   KL I      D   Y+C +      A + V   
Sbjct: 3377 VVTW-RKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQ 3435

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTID-GKKQKL 1163
               +I  L++  V +G+ A F   +   D   V WF D + +  +   ++T+  G    L
Sbjct: 3436 KVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVL 3495

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
             +    L D+G    E G+ + +A L V E+PSI F+  L + + V    D  L  E   
Sbjct: 3496 TLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSI-FSRPLTD-VTVTEGEDLTLVCETTT 3553

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
                V W K    +  + +  L  +  +  L+I   T  D   Y C +  A S++ ++V 
Sbjct: 3554 VDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVH 3613

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
             +  P +  +  ++  +  G   TL     +   P  EW     ++K         +   
Sbjct: 3614 AL--PVRFRESLKDVEVPEGKAATLRCVLSSVAAP-VEWRHGDDVLKSSNKYSLRQEGAV 3670

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
              L I+ ++  D+G Y      +C   D   + T+  K S
Sbjct: 3671 LELVIRDLQPQDSGQY------SCSFGDQTTSATLTVKTS 3704



 Score =  118 bits (283), Expect = 2e-24
 Identities = 129/574 (22%), Positives = 243/574 (42%), Gaps = 47/574 (8%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPD-ENISVAIES 686
            ++ +PP F +  ++Q   EG+   L CR+  A P   + W  KG E + D +  S+  E 
Sbjct: 4653 VKALPPRFIEDLRSQEAREGTVATLRCRMSKAAP---VEWR-KGSETLKDGDRYSLRQEG 4708

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            ++   C  L+I ++       Y+ V    +  A+L +       +  P + IE L+S   
Sbjct: 4709 NL---CE-LQIRDLAVEDTEEYSCVCGQEKTSATLSV-------KALPAKFIEDLRSQEA 4757

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVY 803
             +  +V L  ++  + + ++ W K ++ ++       + DG    + I +   V+D G Y
Sbjct: 4758 PESSTVTLRCKL--SKKASVVWKKGSETLRNGARYSLRQDGAVCELEI-RDLTVEDTGEY 4814

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            +       G   TSA +++  P     +P       Q +  +E     L   ++  P  +
Sbjct: 4815 SCTC----GQERTSATLSIMAPQVVFQQP------LQNLQAEEGSMASLRCELSV-PNAA 4863

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + W +    +           G   EL++ ++  E D+G+Y C    + G  +  A + +
Sbjct: 4864 MVWSKGGLELQGDTRREARQQGCVAELLLRDLRRE-DAGEYSC----TCGSQTTSATLMV 4918

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXX 982
                V F++ LQ + + +EG T  L C+ S   VS +W     ++      +++QEG   
Sbjct: 4919 TAAPVRFLRELQ-AQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTA 4977

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C     ++   L V+   P+F   LQ  E +    A L  +++ 
Sbjct: 4978 ELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSE 5037

Query: 1043 ET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
                  V W ++G  +    +KY+  ++G + +L I      D GEY+C++  +   A +
Sbjct: 5038 AEPGTPVQWLKEGVELHVG-SKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASL 5096

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--D 1157
             V E    I+  L + +V       F  ++++  A  V+W   G  +Q +   ++ +  D
Sbjct: 5097 RVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLAD 5156

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
            G    L++    L+DAG  S  VG    +A LTV
Sbjct: 5157 GCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTV 5190



 Score =  112 bits (269), Expect = 1e-22
 Identities = 113/544 (20%), Positives = 206/544 (37%), Gaps = 33/544 (6%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            K   GN AT   E+T+    V WFKDG ++  S+ +++   G  ++L +      DAGEY
Sbjct: 874  KAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEY 933

Query: 1177 SCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234
            SCE G  K +  L V EP + F    +    +   A   A L+ E+     +VTW+K   
Sbjct: 934  SCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGK 993

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV-EVVEFPPKIVDY 1293
             +  + K  + +    R L++++  + D  EY+C     K + +L V E      K    
Sbjct: 994  KLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQA 1053

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
              E + + G+  TL  +  A  Q    W  + K +      +      S  L +++    
Sbjct: 1054 RSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA 1112

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
            DAG Y    E         ++VT         +P ++           +     GNS  +
Sbjct: 1113 DAGEYS--CEAGGQKLSFRLDVT---------EPKLVFAKEQQARS--EVKAEVGNSATL 1159

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS-----ETT 1468
               V   + + T W        + + ++   +  S R       + D  + S     +  
Sbjct: 1160 SCEVAQAQTEVT-WFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKL 1218

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKA 1527
             +   + E K+     ++    +  E      L+C      Q +VTW++DGKKL  ++K 
Sbjct: 1219 SFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQA-QTEVTWFKDGKKLSSSSKV 1277

Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584
              E                    Y C A    G  + S  + + +  ++    +    + 
Sbjct: 1278 RMEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFHLDVTEPKLVFAKEQQAHSEV 1333

Query: 1585 KVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            K       T   E      EV W+K+G KL +  +  +     +  + +++  ++ + +Y
Sbjct: 1334 KAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEY 1393

Query: 1644 TIEA 1647
            + EA
Sbjct: 1394 SCEA 1397



 Score =  109 bits (261), Expect = 1e-21
 Identities = 87/368 (23%), Positives = 158/368 (42%), Gaps = 36/368 (9%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            +P+ + P  +    AP+F+ +L+ +   DG  + F+C V G P P + WF+   +++   
Sbjct: 6053 VPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDD 6112

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH--GSEMT 612
             + +  D      L+I  V P D G + C+A+N+ G +S+  EL VE   +D+   ++ T
Sbjct: 6113 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADAT 6172

Query: 613  VXXXXXXXXXXXXADILEGIP------PTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDI 665
                         +   EG        P   ++ K   V  G+ +   + ++   P P +
Sbjct: 6173 ETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKL 6232

Query: 666  AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
             W   G+ +   ++I +  +  +H     L+I +V +   G Y     N  G A     L
Sbjct: 6233 YWFKDGQPLTTSDHIRMTDKKTLH----TLEIVSVTREDSGQYAAYISNAVGAAYSSARL 6288

Query: 726  KIK-TGEKE------------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN- 771
             ++   E E            PP+++E      V++G S+  S +V G+P P++ W K  
Sbjct: 6289 LVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEE 6348

Query: 772  -NKPVKALPTKSDGDT-------HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
              K V  +   + G T       HS+ +L   + + +G YT  A N  G A  SA + + 
Sbjct: 6349 AEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGR-QHQGTYTCIATNPAGQALCSASLHIS 6407

Query: 824  EPTEENAE 831
               +E  +
Sbjct: 6408 GLAKEEEQ 6415



 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 176/932 (18%), Positives = 359/932 (38%), Gaps = 87/932 (9%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  F KK + Q V+E + + LE  L   P P++ W      + P EN+ +  E   H  C
Sbjct: 2420 PVLFKKKLEPQTVEERTSVTLEVELTR-PWPEVKWTRNAAVLTPSENVEIRAEGARH--C 2476

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             VL+  +V     G +     + + +A L +       E    +++  L+ +  ++  + 
Sbjct: 2477 LVLR--SVGFADRGFFGCETPDDKTQAKLNV-------EMRQVRLVRGLQEVEAKEQGTA 2527

Query: 753  ILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             +  + + +     +W ++    +P         G  H +T L   + +D G+   +A  
Sbjct: 2528 SMDVE-LSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILT-LSALQPQDSGLVAFRA-- 2583

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
             EG+  ++ +I  E P         F    Q++   +K  + L   ++R PV  + W ++
Sbjct: 2584 -EGVHTSARLIVTELPVS-------FTRVLQDVVATQKEKVTLECELSR-PV-DVRWLKD 2633

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC---VASNSAGKSSHGARVTI--- 923
               +   + I     G    LVI   ++  D G Y C    A  SA     G   T+   
Sbjct: 2634 GVELRAGKAIGIVAQGTCRSLVIYRCETG-DQGVYVCDALDAQTSASLRVQGRTYTLIFR 2692

Query: 924  -----DVEKVTFV-------KHLQ------------KSYETEEGKTVILECQTSH-TVST 958
                 D  +V FV        HL+            +     E    +LECQ S  +   
Sbjct: 2693 RVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQV 2752

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018
            +W+    E+      E++ +G             D     C   + +TS    V+E    
Sbjct: 2753 RWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSIT 2812

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
             +R L+D  V E   A  E E +  +        G+ +         E+ G + +L +  
Sbjct: 2813 IVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHK 2872

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138
            T     G     +     +A++ V ++P  +   L+ +   +        +       V+
Sbjct: 2873 TCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQ 2932

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF 1198
            W+KD + +  S   ++ ++G+  +L+I      DAG Y C+ G+++ +A +TVE   +  
Sbjct: 2933 WYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTV 2992

Query: 1199 TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
               L +   +      + + E+  +  D+ W    + + +     +  +    TL+++  
Sbjct: 2993 IQPLQDAEAMEEGRVCF-SCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSV 3051

Query: 1259 TEDDQ---CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
             + D    C  T   +   +   +K + V F   + D   E   +RG+ +TL  +  + P
Sbjct: 3052 RQADTGTVCA-TSPKVSVSARLVVKGKPVVFLKALDDVSAE---ERGT-LTLQCEV-SDP 3105

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
            +    W  +   +           + +  LT+  + + DAG+Y  ++ +    + V ++ 
Sbjct: 3106 EARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHD 3165

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKNIT 1434
              +          +LE +S S   C    E+  +  +  + V  + +  +  + +V+   
Sbjct: 3166 LHVGITKRLKTVEVLEGESCSFE-CVLSHESPSDPAV--WTVGGKTVGGSGHFHAVRQGR 3222

Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
            K   ++++   + +         EV  S    T++   +I+E  +    + KPL++  T 
Sbjct: 3223 KYTLTVKDAALSDA--------GEVVFSVLGLTSKASLIIRERPVD---ITKPLEDQRTT 3271

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
              ED+ L+C         V W +DGK ++ ++
Sbjct: 3272 LGEDVMLSCELSRA-GTSVRWLKDGKAIRKSQ 3302



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 84/330 (25%), Positives = 137/330 (41%), Gaps = 17/330 (5%)

Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
           L V  + T  EQ  AP F+ +       +G+   F C+V G P+P ++W +    + P  
Sbjct: 96  LRVDSEGTCAEQ--APHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPD 153

Query: 555 DFQMYYDDDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT- 612
              +  ++   ++ L IR   P D GT+   A+N  G AS+   L+V++     G   T 
Sbjct: 154 APHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTS 213

Query: 613 VXXXXXXXXXXXXADILEGIPPT-FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671
                        A   EGIPP+      +   V EG    L C +   P+P+  W  K 
Sbjct: 214 TATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWK-KD 272

Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
            ++V +    V  E +   +  VLKI   K+   G YT  A N  G+    +++ ++  E
Sbjct: 273 GQLVTEGRRHVVYEDEQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR--E 328

Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHS 788
              P   + L+ + VR+ ES     + V  P     W K    + A      + +G    
Sbjct: 329 PTVP-FKKRLQDLEVREKESATFQCE-VAQPATEAAWFKEETRLWASAKYDIEEEGTERR 386

Query: 789 ITILKPKKVKDEGVYTLK-AENSEGIAETS 817
           +T+ +     D+ VY  +  E S  +AE S
Sbjct: 387 LTV-RNVSADDDAVYICETTEGSRTVAELS 415



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 14/294 (4%)

Query: 1046 DVVWERDGEIIKPKKNK--YDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEV 1100
            + VW++DG+++   +    Y+ E+   + K+     S  D G Y+C    L  ++ ++ +
Sbjct: 266  ETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQS--DRGLYTCTASNLVGQTYSSVL 323

Query: 1101 TVVELPP-EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
             VV  P      RLQ+ +V +   ATF+ E+ +      WFK+ + +  S    +  +G 
Sbjct: 324  VVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGT 383

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
            +++L + +   DD   Y CE    S+  A L+V+    N T +LP    V     A   V
Sbjct: 384  ERRLTVRNVSADDDAVYICETTEGSRTVAELSVQG---NLTRKLPRKTAVRTGDTAIFWV 440

Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
            E+      V W + +  +    +  + ++    TL I +CT +D  E   V    ++TT+
Sbjct: 441  ELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQ 500

Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
              V     PP     +   + K  S VTL   + A P  +    ++  +++K K
Sbjct: 501  FCVSAPRRPPLYPPADPVVKAKTESSVTL--SWSAPPHGDRPVTIDGYVLEKRK 552



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 58/227 (25%), Positives = 95/227 (41%), Gaps = 11/227 (4%)

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
            +V+K+     TV+  N   +    I  ++      PP+  E L       GE+V L+ +V
Sbjct: 6918 SVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRV 6977

Query: 759  VGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
             G P+P ++W K+ KPV+  P      D D     IL      D G Y   A ++ G A 
Sbjct: 6978 TGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNAS 7037

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
            T   I V+        PP F+N+ +     E    ++   V   P P I WY++  +++P
Sbjct: 7038 TLGKILVQ-------VPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAP 7090

Query: 876  SETITQ-NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
                   N     + +++    S+ D G Y+C   N  G +  G  +
Sbjct: 7091 GNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGEL 7137



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 84/400 (21%), Positives = 160/400 (40%), Gaps = 29/400 (7%)

Query: 1139 WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEE 1193
            W KDG  + +   H+    + +   LKI  C   D G Y+C     VG +  + ++ V E
Sbjct: 269  WKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 328

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
            P++ F  RL + + V     A    E+     +  W+K+++ +  + K+ +  +  +R L
Sbjct: 329  PTVPFKKRLQD-LEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRL 387

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
             +R  + DD   Y C   +   T  +L V+      K+    R+  ++ G      V+  
Sbjct: 388  TVRNVSADDDAVYICETTEGSRTVAELSVQG-NLTRKL---PRKTAVRTGDTAIFWVEL- 442

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
            A P+    W+ N + +        + +    +LTI +    D G     +   C     +
Sbjct: 443  AVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAF-VSGGC-RTTTQ 500

Query: 1373 MNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNS-TIIYYVVEYQEIDTTEWIS 1429
              V+   +P   PP  P +     SS+ + W  P +     TI  YV+E +++    W  
Sbjct: 501  FCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSR 560

Query: 1430 VKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
                  +  T+ +I  +     ++FR  A+N        E      ++    +++P   K
Sbjct: 561  CHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPL--K 618

Query: 1487 PLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
             ++ +   E    ++LT    G       W+ DG+ LK +
Sbjct: 619  AVEAVEGGEVTFSVDLTVASSG------EWFLDGEALKAS 652



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 48/169 (28%), Positives = 75/169 (44%), Gaps = 8/169 (4%)

Query: 1585 KVGDEWLVTAVI-EGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K G +   T ++ E +P  E  WY NG  ++ +D ++ +TT      + +   +  H+ +
Sbjct: 5386 KAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGE 5445

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
             T  A +   ++ + V L + D P   E  V+ R  S  SVT+ W  P+ DGG  L  Y 
Sbjct: 5446 VTFAARDAVASARLSV-LALPDPPEDAE--VVGR--SDHSVTLSWVAPMSDGGGGLCGYR 5500

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            +E  E    +W    D+    E   +  L     Y FRV A  P G  E
Sbjct: 5501 VEMKEASTGQWQLCHDLVPGPEC-VVDDLVPGKTYRFRVAAVGPAGAGE 5548



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 58/216 (26%), Positives = 96/216 (44%), Gaps = 22/216 (10%)

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALP--TKSDG 784
            ++ E + PQV+E LK + V  G  +     +V G P P + W K+ +P+        +D 
Sbjct: 6193 ESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDK 6252

Query: 785  DT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE----------ENAEPP 833
             T H++ I+   + +D G Y     N+ G A +SA + V  P+E          E   PP
Sbjct: 6253 KTLHTLEIVSVTR-EDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPP 6311

Query: 834  LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-----IISP-SETITQNFDGEN 887
              + +F    VK   +I    +V  +P PS+ W +         I P +   T     + 
Sbjct: 6312 RILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQ 6371

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              LV+ +V  +   G Y C+A+N AG++   A + I
Sbjct: 6372 HSLVLLDVGRQ-HQGTYTCIATNPAGQALCSASLHI 6406



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 43/180 (23%), Positives = 73/180 (40%), Gaps = 9/180 (5%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXX 1536
            P  E+ L + T E  E ++L C   G P+P V+WY+DGK ++           +      
Sbjct: 6954 PEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLI 7013

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y C A +  G   T   + +Q  P     N+        G++  +T  +
Sbjct: 7014 LDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPP--RFVNKVRATPFVEGEDAQITCTV 7071

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTS 1654
            EG P P++ WYK+G  L     Y +  + ++   V+ I+   +     Y  E  N  G++
Sbjct: 7072 EGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGST 7131



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568
            P FV K+R     +G   Q  C VEG P PQI W++   ++ P   ++M  +    V  L
Sbjct: 7048 PRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVL 7107

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            VI+    ED G + C   N  G      EL +++P
Sbjct: 7108 VIQAASKEDLGHYECELVNRLGSTRGGGELYMQSP 7142



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 7/119 (5%)

Query: 499  EKPTSE--EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-----IK 551
            EKP S+  E+ + P  +EK  PK    GS++ F  +VEG+P P + W ++ A      I 
Sbjct: 6298 EKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIG 6357

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
            P              +LV+ +V  +  GT+TC+A N AG A  +  L +     +   E
Sbjct: 6358 PDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQE 6416



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 49/212 (23%), Positives = 97/212 (45%), Gaps = 8/212 (3%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIE 889
            PP F     + T +   T+KL  RVT  P P ++WY++ + +   P   + ++ DG +  
Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDG-SCT 7011

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTVIL 948
            L++ N+   IDSG Y C A+++AG +S   ++ + V    FV  ++ +   E E   +  
Sbjct: 7012 LILDNLTG-IDSGQYMCFAASAAGNASTLGKILVQVPP-RFVNKVRATPFVEGEDAQITC 7069

Query: 949  ECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX--XXXXXXXXXXXDVGVIKCIVKDQET 1006
              + +     +WY +   ++  +   ++ E R              D+G  +C + ++  
Sbjct: 7070 TVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLG 7129

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
            ST    +  +     + +D   +E+ VA +EV
Sbjct: 7130 STRGGGELYMQSPALRARDQHHREQIVAAVEV 7161



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G   QF+  +EG+P P +TW++ +  +  S        D    +LV+ +V P DAG +TC
Sbjct: 7319 GDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQR-QDGTTYSLVLTDVAPHDAGVYTC 7377

Query: 584  VAKNAAGFASSTTELIV 600
            VA NA G      EL+V
Sbjct: 7378 VANNAGGQVLCKAELLV 7394



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 28/94 (29%), Positives = 50/94 (53%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F E+L       G TV+  C+V G P+P ++W++    ++      +  D D   TL+
Sbjct: 6954 PEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLI 7013

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +  +   D+G + C A +AAG AS+  +++V+ P
Sbjct: 7014 LDNLTGIDSGQYMCFAASAAGNASTLGKILVQVP 7047



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 14/200 (7%)

Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
            L  P+  +V    DA L+ +I  + T  V+W K +  +E   +F L  D     L I   
Sbjct: 12   LTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDL 71

Query: 1259 TEDDQCEYTC----VLLDAKSTTKLKVE----VVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
               D  +Y C     + +A +   L+V+      E  P  +      R++ G+D T    
Sbjct: 72   ALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCR 131

Query: 1311 YQAFPQPNDEWIVNSKII--KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                PQP   W  + + +      H +     +S++L I+     D G Y++R EN  G 
Sbjct: 132  VGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGS 191

Query: 1369 ADVEMNVTI---LDKPSPPG 1385
            A     + +    +   PPG
Sbjct: 192  ASAAAALVVDSDAEVAGPPG 211



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 1/116 (0%)

Query: 816  TSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
            T AV   + P  + ++  P+F+   Q   V++   +     VT  PVPS+ W+++ +++ 
Sbjct: 6050 TPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLE 6109

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +    N D +    +I       D G Y+C+A NS G SS  A + +++    +
Sbjct: 6110 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDY 6165



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 7/139 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F ++      + G  + L CR+   P+P ++W   G+ +  D +  + IE D    C
Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPH-HILIE-DPDGSC 7010

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +++ + N+     G Y   A +  G AS    + ++     PP+ +  +++    +GE  
Sbjct: 7011 TLI-LDNLTGIDSGQYMCFAASAAGNASTLGKILVQV----PPRFVNKVRATPFVEGEDA 7065

Query: 753  ILSAQVVGNPRPTITWCKN 771
             ++  V G P P I W K+
Sbjct: 7066 QITCTVEGAPYPQIRWYKD 7084



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 8/141 (5%)

Query: 809  NSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            +S+ I ET+    V + P       P      +++ V+     +  A +  +P P +TWY
Sbjct: 7280 HSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWY 7339

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923
            + +  ++ S  ++Q  DG    LV+T+V +  D+G Y CVA+N+ G+    A + +    
Sbjct: 7340 KGSTQLTSSARLSQRQDGTTYSLVLTDV-APHDAGVYTCVANNAGGQVLCKAELLVHGGD 7398

Query: 924  --DVEKVTFVKHLQKSYETEE 942
              D E   + + L   Y+ +E
Sbjct: 7399 KLDAENQVYRRKLHSFYDVQE 7419



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 46/234 (19%), Positives = 90/234 (38%), Gaps = 11/234 (4%)

Query: 1228 TWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
            TW      +  +EK  ++   +  +  L+++     D C  T +  D  ++  L V    
Sbjct: 5314 TWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWR 5373

Query: 1286 FPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHT-KPSIDSKSA 1343
               ++++   +  +K G  V    +  +A P     W +N   I+        + D    
Sbjct: 5374 L--EVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHH 5431

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
            +LT+   +   AG       +    A     +++L  P PP    ++     S+ + W  
Sbjct: 5432 ALTLSNAQPQHAGEVTFAARDAVASA----RLSVLALPDPPEDAEVVGRSDHSVTLSWVA 5487

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456
            P + G   +  Y VE +E  T +W    ++    +  + +L    +YRFR  AV
Sbjct: 5488 PMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAV 5541



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 28/90 (31%), Positives = 40/90 (44%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
            +  AP F+ +L  +    G +V   CQV   P  Q TW +   +++ S    +     N 
Sbjct: 8381 RDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNF 8440

Query: 566  ATLVIREVFPEDAGTFTCVAKNAAGFASST 595
              L I  V  ED GT+TC   N  G A +T
Sbjct: 8441 QLLTILVVKEEDLGTYTCCVSNPLGTAVTT 8470



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 2/98 (2%)

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
            G+ + P + ++ ED++ +  VGD     AVIEG PPP V WYK   +L +    +     
Sbjct: 7300 GVTRAPSMQVTIEDVQVQ--VGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDG 7357

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
             T  + + ++    +  YT  A+N  G    +  L V+
Sbjct: 7358 TTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVH 7395



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 4/145 (2%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVV 1284
            V+WYK    +E      LI D     TLI+   T  D  +Y C    A  + + L   +V
Sbjct: 6985 VSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILV 7044

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343
            + PP+ V+  R      G D  +    +  P P   W  +  ++      +   + +S  
Sbjct: 7045 QVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGV 7104

Query: 1344 -SLTIKKVENTDAGIYKLRLENNCG 1367
              L I+     D G Y+  L N  G
Sbjct: 7105 LVLVIQAASKEDLGHYECELVNRLG 7129



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT--NYIIEFKTVKGKSWTKIVTVGG 1920
            L PP+ P   VV   T  SVTL W+ P  +G  P+T   Y++E + +   +W++    G 
Sbjct: 511  LYPPADP---VVKAKTESSVTLSWSAP-PHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGW 566

Query: 1921 -SVHEHCIENIKEKDEIIFRISAENTVG 1947
             +  E  I  + E+ +  FR+SA N  G
Sbjct: 567  LATTEFTITGVAEEGDFQFRVSAINHFG 594



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 3/123 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-- 1653
            ++G P P++ W+K+G  L       +T K+    + I  + R  S +Y    SN  G   
Sbjct: 6224 VKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAY 6283

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNR 1712
            SS  + ++   +P +     +   +    +  ++ P     G  +T    +E H   +  
Sbjct: 6284 SSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVH 6343

Query: 1713 WIK 1715
            W+K
Sbjct: 6344 WLK 6346



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 4/110 (3%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD 785
            TG    P +   ++ + V+ G+     A + G+P P +TW K +  + +   L  + DG 
Sbjct: 7299 TGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGT 7358

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
            T+S+ +L      D GVYT  A N+ G     A + V    + +AE  ++
Sbjct: 7359 TYSL-VLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVY 7407



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 28/191 (14%)

Query: 1107 PEIITRLQNQKVNKGNK-ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            P+++  L++ +V  G + A F++++    A  + WFKDG  +  S+HI++T       L+
Sbjct: 6200 PQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLE 6259

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTV-----------EEPSINFTLRL-PEFIL----- 1207
            I     +D+G+Y+  + N+   A  +            E+P+ +   RL P  IL     
Sbjct: 6260 IVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTP 6319

Query: 1208 --VPANTDAYLTVEIPDETL-DVTWYK---KKSVI---EDTEKFTLISDVKKRTLIIRKC 1258
              V   +    +V++       V W K   +K V+    DT  +T+ S  K+ +L++   
Sbjct: 6320 KKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDV 6379

Query: 1259 TEDDQCEYTCV 1269
                Q  YTC+
Sbjct: 6380 GRQHQGTYTCI 6390



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 43/197 (21%), Positives = 75/197 (38%), Gaps = 16/197 (8%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544
            K       +D  L+C   G P P V+W +D + ++       A   +             
Sbjct: 16   KAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGD 75

Query: 1545 XXXYKCIAFNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
               Y C A N  GE   +  + +       +Q P   +    I+ +   G +      + 
Sbjct: 76   SGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVRE--GADATFRCRVG 133

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            G P P V W K+G +L      ++  +E  ++S +RI+  +      Y + A N  G++S
Sbjct: 134  GSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSAS 193

Query: 1656 VEVTLKVYDKPSKPEGP 1672
                L V D  ++  GP
Sbjct: 194  AAAAL-VVDSDAEVAGP 209



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 43/204 (21%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PPE    L +     G        +T     +V W+KDG  ++   H  L  D       
Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 7012

Query: 1165 IYD-CDLDDAGEYSC----EVGNSKCTAILTVEEPS--INFTLRLPEFILVPANTDAYLT 1217
            I D     D+G+Y C      GN+     + V+ P   +N  +R   F+      DA +T
Sbjct: 7013 ILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVN-KVRATPFV---EGEDAQIT 7068

Query: 1218 VEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAK 1274
              +       + WYK  +++    ++ ++++ +     L+I+  +++D   Y C L++  
Sbjct: 7069 CTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRL 7128

Query: 1275 STTKLKVEVVEFPPKIVDYEREYR 1298
             +T+   E+    P +   ++ +R
Sbjct: 7129 GSTRGGGELYMQSPALRARDQHHR 7152



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 2/144 (1%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKK-QKLK 1164
            P  +  L ++ V  G   T   + L +  A   W KDG  ++ S H+ ++   K  Q L 
Sbjct: 8385 PSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLT 8444

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I     +D G Y+C V N   TA+ T            P   +     DA L V  P E+
Sbjct: 8445 ILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVES 8504

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDV 1248
                 Y  +  IE     TL SD+
Sbjct: 8505 CGPVTYIVQCCIEGGSWTTLASDI 8528



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 9/151 (5%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            P  +  W K+G  LE+     I++  K   ++ I  +K      YT   SN  GT+    
Sbjct: 8412 PTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTG 8471

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE-LTKYAIEKHEPDNNRWIKVA 1717
             L+  ++PS    P +  E+ +++V + WKP    G +  + +  IE        W  +A
Sbjct: 8472 VLRKAERPSSSPRPEV-GELYKDAVLLVWKPVESCGPVTYIVQCCIE-----GGSWTTLA 8525

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                D   Y   KL+    Y+FR    +  G
Sbjct: 8526 SDISDC-CYLTGKLSRGGMYIFRTACVSKAG 8555



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 6/110 (5%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            L  P  P +  V   +  SVTL W  P S+GG  +  Y +E K      W     +    
Sbjct: 5462 LALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPG- 5520

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
             E  ++++       FR++A    G   P     V L + A  P+P  AP
Sbjct: 5521 PECVVDDLVPGKTYRFRVAAVGPAGAGEP-----VHLPQMAPAPAPAPAP 5565



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 6/170 (3%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKL 1360
            G  VTL     A P     W  +  +++   H   S   K+  L TI  V+  D G Y  
Sbjct: 8399 GQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTC 8458

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
             + N  G A     +   ++PS   +P + E+   ++ + W   E+ G  T   Y+V+  
Sbjct: 8459 CVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVT---YIVQCC 8515

Query: 1421 EIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             I+   W ++  +I+        L     Y FR   V++  +   S  +E
Sbjct: 8516 -IEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSE 8564



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 6/102 (5%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F+E LR +  P+ STV   C++    +  + W + +  ++    + +   D  V  L IR
Sbjct: 4748 FIEDLRSQEAPESSTVTLRCKLS--KKASVVWKKGSETLRNGARYSL-RQDGAVCELEIR 4804

Query: 572  EVFPEDAGTFTCVA---KNAAGFASSTTELIVEAPLSDHGSE 610
            ++  ED G ++C     + +A  +    +++ + PL +  +E
Sbjct: 4805 DLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAE 4846



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%)

Query: 509  API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            AP+ F+ +L+ +   +G+T +  C++       + W + +  + P   +QM   +   A 
Sbjct: 4921 APVRFLRELQAQDVDEGATARLRCELSR-EAVSVEWRKGSLQLFPCAKYQMV-QEGTTAE 4978

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            L++  V  EDAG +TC     AG   S   L V AP
Sbjct: 4979 LLVHGVEQEDAGEYTC----DAGHTQSIARLSVRAP 5010



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 2/79 (2%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGK-KQKLK 1164
            P  +T LQNQ V  G   +F+  +T      VRWFKDG  ++  +H  +  D +   +L 
Sbjct: 6068 PVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 6127

Query: 1165 IYDCDLDDAGEYSCEVGNS 1183
            I      D G Y C   NS
Sbjct: 6128 ITAVVPADMGVYRCLAENS 6146



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGD 785
            G  + P  +  L    V  G+SV L+ QV+  P    TW K+   +++    L + +  +
Sbjct: 8380 GRDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKN 8439

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
               +TIL  K+ +D G YT    N  G A T+ V+   E    +  P
Sbjct: 8440 FQLLTILVVKE-EDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRP 8485



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 49/224 (21%), Positives = 85/224 (37%), Gaps = 9/224 (4%)

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSH-GARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
            E  IT V  E D   ++  A N  G+  +     T+ +  +  VK   K+ E  EG  V 
Sbjct: 571  EFTITGVAEEGDF-QFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVT 629

Query: 948  LECQTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
                 +   S +W+ + + +       I     R                +K +    ET
Sbjct: 630  FSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIET 689

Query: 1007 STMLVVKETIPEFIRKLQDFEVKE-----KDVAILEVEINSETADVVWERDGEIIKPKKN 1061
            S  +VV+  +     KL     +E      + A L  E++ + A V W +DG  +     
Sbjct: 690  SIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGP- 748

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            KY+ +     R L +R+ +  D G Y C+ R      ++ V ++
Sbjct: 749  KYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDI 792



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 20/65 (30%), Positives = 31/65 (47%)

Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
            EL+   A V W KDG E+      ++ +   ++ L + D   DDAG Y C    S+    
Sbjct: 727  ELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQ 786

Query: 1189 LTVEE 1193
            L V++
Sbjct: 787  LLVQD 791



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 13/142 (9%)

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971
            WT  VT  GS H   + N + +       +A + V         S RL   A +P PP  
Sbjct: 5422 WT--VTTDGSHHALTLSNAQPQHAGEVTFAARDAVA--------SARLSVLA-LPDPPE- 5469

Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031
              E+     + V  SW  P  DGG  L GY + +++ +   W     + V   +  + DL
Sbjct: 5470 DAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDL-VPGPECVVDDL 5528

Query: 2032 SENHTYMIRIYARNEIGLSEPL 2053
                TY  R+ A    G  EP+
Sbjct: 5529 VPGKTYRFRVAAVGPAGAGEPV 5550



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 1/104 (0%)

Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
            VH +       R   C A  T V   P +   +++ +V  G+ A F+  +      +V W
Sbjct: 7279 VHSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTW 7338

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            +K  +++  S  +    DG    L + D    DAG Y+C   N+
Sbjct: 7339 YKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNA 7382



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 5/89 (5%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIK 1633
            + N+D++  + +  + +VT    G P P V W+K+G  LE D  Y I   ++    + I 
Sbjct: 6074 LQNQDVQDGYPMSFDCVVT----GQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIIT 6129

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             +  +    Y   A N+ G SS +  L+V
Sbjct: 6130 AVVPADMGVYRCLAENSMGVSSTKAELRV 6158



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 38/181 (20%), Positives = 70/181 (38%), Gaps = 12/181 (6%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXX---XXX 1543
            +  T    +   L+C   G P+P+  W +DG+ +   +    YE+               
Sbjct: 243  RTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQS 302

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPP 1602
                Y C A N  G+  +S +V +++    T+  +   Q  +V ++   T   E   P  
Sbjct: 303  DRGLYTCTASNLVGQTYSSVLVVVREP---TVPFKKRLQDLEVREKESATFQCEVAQPAT 359

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY---TIEASNTAGTSSVEVT 1659
            E  W+K   +L    +Y+I  +     + ++ +     + Y   T E S T    SV+  
Sbjct: 360  EAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGN 419

Query: 1660 L 1660
            L
Sbjct: 420  L 420



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKYTIEASNT 1650
            ++  + G P PE +W K+G  +   + + +   E+ + V++I   K+S    YT  ASN 
Sbjct: 255  LSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNL 314

Query: 1651 AGTSSVEVTLKVYDKPSKP 1669
             G +   V L V  +P+ P
Sbjct: 315  VGQTYSSV-LVVVREPTVP 332



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 509  API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            AP+ F +KL P+   + ++V  E ++   P P++ W R  A++ PS++ ++  +      
Sbjct: 2419 APVLFKKKLEPQTVEERTSVTLEVELTR-PWPEVKWTRNAAVLTPSENVEIRAEGAR-HC 2476

Query: 568  LVIREVFPEDAGTFTC 583
            LV+R V   D G F C
Sbjct: 2477 LVLRSVGFADRGFFGC 2492



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T   +++ P F+E LR +   +G+     CQ+       + W + +  ++    + +   
Sbjct: 4474 TLSVKALPPRFIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGSETLRDGDRYSL-RQ 4530

Query: 562  DDNVATLVIREVFPEDAGTFTCV 584
            D  V  L IR++  EDAG + CV
Sbjct: 4531 DGAVCELQIRDLAVEDAGEYLCV 4553



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 28/130 (21%), Positives = 49/130 (37%), Gaps = 7/130 (5%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            FV +LR K   +G T   +C++       + W + T  ++    + +   D  V  L IR
Sbjct: 3796 FVRRLRSKEATEGDTTTLQCELS--KAAPVEWRKGTETLRDGDRYSL-KQDGAVCELQIR 3852

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
             +   DAG + C      G   ++  L V A  +     +               ++ + 
Sbjct: 3853 SLTIADAGEYLC----TCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKA 3908

Query: 632  IPPTFSKKPK 641
             P T+ K PK
Sbjct: 3909 APVTWKKGPK 3918



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            LE+E+ ++  +VVW +  E I+P    ++   RG  + L I+     D+GEY C
Sbjct: 5582 LELEVAADGGEVVWHKGTERIQP-GGHFEVLSRGQRQMLVIKGFRTEDQGEYRC 5634



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            FV KLR K   +G+TV   C++       + W + T  ++    + +   D  V  L I 
Sbjct: 3708 FVGKLRNKEATEGTTVTLRCELT--KEAPVEWKKGTETLRNGDKYSL-KQDGAVCELQIC 3764

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             +   DAG ++CV       A+ T + ++
Sbjct: 3765 SLLVADAGEYSCVCGQEKTSATLTVKALL 3793



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%)

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            +P   ++W K G +L+ D       +   + + +++L+R  + +Y+    +   ++++ V
Sbjct: 4859 VPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMV 4918

Query: 1659 T------LKVYDKPSKPEGPV--IMREISRESVTIEWK 1688
            T      L+        EG    +  E+SRE+V++EW+
Sbjct: 4919 TAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWR 4956



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 20/83 (24%), Positives = 35/83 (42%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            + P F+    +  V    ++ L  +V   P    TW ++  ++  S  +  +   +N +L
Sbjct: 8383 QAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQL 8442

Query: 891  VITNVDSEIDSGDYKCVASNSAG 913
            +   V  E D G Y C  SN  G
Sbjct: 8443 LTILVVKEEDLGTYTCCVSNPLG 8465



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T   +++ P F+E LR +   +G+     CQ+       + W + +  ++    + +   
Sbjct: 4298 TLNVKALPPRFIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGSETLRDGGRYSL-RQ 4354

Query: 562  DDNVATLVIREVFPEDAGTFTCV 584
            D  V  L I ++  EDAG ++CV
Sbjct: 4355 DGAVCELQIHDLDVEDAGQYSCV 4377



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 16/168 (9%)

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITIL 792
            V+  L+++   +G   +   Q+        TW  +++PV    K      +     + +L
Sbjct: 5284 VLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLL 5343

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            K  K +D    T  A    G   TSA +TV     E  EPP       + +VK    ++ 
Sbjct: 5344 KNLKPQDSCRVTFLA----GDVVTSAFLTVRGWRLEVLEPP------HDASVKAGMQVRF 5393

Query: 853  VARVTRN-PVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSE 898
               ++   PV   TWY N   I P +T  T   DG +  L ++N   +
Sbjct: 5394 TCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQ 5441


>UniRef50_UPI0000F1EF40 Cluster: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein; n=2;
            Danio rerio|Rep: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein - Danio
            rerio
          Length = 1523

 Score =  198 bits (482), Expect = 2e-48
 Identities = 244/1095 (22%), Positives = 443/1095 (40%), Gaps = 93/1095 (8%)

Query: 628  ILEGIPPTFSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
            IL+  P TF+  P+      + E  +ILL C+ V+  +    W   G E+    N+ + +
Sbjct: 327  ILQSPPVTFAYIPEDDLHRNIVEQDNILLHCQ-VSRSDATAQWYKDGVELKSTSNVLIEV 385

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKS 743
            E+D+      L I +      GTYT     R G+++L  V K+    +EPP  ++ P + 
Sbjct: 386  ENDIRR----LIILSAHLSDSGTYTC----RAGDSAL--VFKVNV--REPPVMIVYPKED 433

Query: 744  MIVRQG--ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK 798
            + + +   E ++LS ++   P   +TW K+ + ++    +  K++G    + IL    ++
Sbjct: 434  VHLDRHVPEEIVLSCEL-SRPNGKVTWFKDGQKLQESENIKLKTEGPYRRLKILH-SGIE 491

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            D G Y     +          + ++EP      P        E+  +    + L   ++R
Sbjct: 492  DSGEYVCDTADDSIFFN----LNIKEPPVRIVSPS---QSQMELCQQTSERMVLSCEISR 544

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P  ++ WYR+   +  S+++    DG    L+I     + DS +Y C  ++     S  
Sbjct: 545  -PNATVRWYRDGLEVEESDSLILEVDGVYRRLIIPKPTVK-DSAEYVCDTTDD----SVT 598

Query: 919  ARVTIDVEKVTFVKHLQKSYETEE--GKTVILECQTSH-TVSTKWYHNKKEISGMDHREI 975
              V I    V F++  + +Y  E+  G+ V+LEC+         W  +  EI    +  I
Sbjct: 599  FFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVLECEVCRPNAEVSWKKDGDEIEENSNVTI 658

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---- 1031
             ++G             D G   C  +D     ++ +K+   + +RK  D E K +    
Sbjct: 659  TEDGTNRQLTIHSADFEDAGQYVCDARDDVMDFLVKIKDPPLKILRKA-DIETKRQFMVS 717

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
            D  +L+ EI+     V W +D E I   ++ +  E+ G  R L + N  + D GEY C  
Sbjct: 718  DAIVLKCEISRANGVVNWLKDNEKIDGNEH-FTCEEEGAFRSLIVLNAELRDSGEYICDA 776

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
            +D+     VTV E P  I+   Q  K   +  G++ + E E+++ +A+V+W+ +G  ++ 
Sbjct: 777  QDDKVVFSVTVEEAPVSIVGNTQKPKHCILLTGDELSLECEVSRVNAVVQWYCNGRLLKQ 836

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             +   +      +KL I      D+GEY C+  + K   +LTV++    F ++  E   +
Sbjct: 837  DSRTHIESSDTMRKLVISGLQTSDSGEYLCDATDDKMITMLTVQDLPFKF-IKKDEKTNI 895

Query: 1209 PANTDAYLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             A  +  LT+      ++  + W + + +I   ++F   SD     L I      D  EY
Sbjct: 896  SAYEEDSLTLRATVNRVNAPIKWQRGRDLIRG-DRFNTTSDGNTHYLTINPLKRGDSGEY 954

Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            TC L          V V     K           +GS+V L  +     + + +W+ +S+
Sbjct: 955  TCHL--GTDEMHFSVHVKAMKVKFSKPLENIAGLKGSNVVLKCELYK-SKGDVQWLKDSQ 1011

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV-TILDKPSPPG 1385
             I   +H     + +  SLTI  +   DAG Y    ++    A V +N+  I++  +   
Sbjct: 1012 EIAASRHFTIRAEGRVRSLTIHNITEDDAGEYACESKDERTSATVMVNIPRIVEFVAELH 1071

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLK 1444
               ++E + ++   C   PE+   S    +    Q I + E  ++  N       I+N +
Sbjct: 1072 NMTVMEGEDATFK-CVVSPEDAKLS----WFKNGQHISSNEKFNISSNGLCHMLHIKNCQ 1126

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
             + S    A A  E  IS A    +  +V+  TK   P V +     T E     E    
Sbjct: 1127 VSDSCSLTAEA--EGVISRALLQVQEAQVL-FTKSMDPVVAEEFGEATLEVEVSTETA-- 1181

Query: 1505 FGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
                   +V W R G  +   +K T      +               Y C   +D  + +
Sbjct: 1182 -------EVQWMRQGVVIHPGSKFTLRQSGRKRSLTIHKLTLLDRGTYSCETLHDRTQAK 1234

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             S      +K  I     DI+   +    + V      +   E +W K+G+ L+ +    
Sbjct: 1235 LSVE---PRKIKIRKGLTDIQTIERETASFEVELSHSNV---EGVWQKDGHVLKTNNRLR 1288

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV------TLKVYDKPSKPEGP-- 1672
            +T + +   + I  L    +  Y     N    + ++V       LK  D   +PEG   
Sbjct: 1289 MTAQGRVHSLTISGLTLDDTGTYIFSVDNVRSLARLDVKEIPVSILKKLDDIRQPEGSGV 1348

Query: 1673 VIMREISRESVTIEW 1687
             +  E+SR ++ I+W
Sbjct: 1349 TLECELSRHNIDIKW 1363



 Score =  169 bits (412), Expect = 5e-40
 Identities = 174/733 (23%), Positives = 304/733 (41%), Gaps = 40/733 (5%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            ++KPK   +  G ++ LEC +  +    + W   G  +  D    +     M      L 
Sbjct: 798  TQKPKHCILLTGDELSLECEVSRV-NAVVQWYCNGRLLKQDSRTHIESSDTMRK----LV 852

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            I+ ++    G Y   A + +    L +  L  K  +K+    I   +       +S+ L 
Sbjct: 853  ISGLQTSDSGEYLCDATDDKMITMLTVQDLPFKFIKKDEKTNISAYEE------DSLTLR 906

Query: 756  AQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            A  V      I W +    ++     T SDG+TH +TI  P K  D G YT       G 
Sbjct: 907  A-TVNRVNAPIKWQRGRDLIRGDRFNTTSDGNTHYLTI-NPLKRGDSGEYTCHL----GT 960

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
             E    + V+    + ++P       + I   +   + L   + ++    + W ++++ I
Sbjct: 961  DEMHFSVHVKAMKVKFSKP------LENIAGLKGSNVVLKCELYKSK-GDVQWLKDSQEI 1013

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVK 932
            + S   T   +G    L I N+ +E D+G+Y C + +   ++S  A V +++ ++  FV 
Sbjct: 1014 AASRHFTIRAEGRVRSLTIHNI-TEDDAGEYACESKDE--RTS--ATVMVNIPRIVEFVA 1068

Query: 933  HLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
             L  +    EG+    +C  S       W+ N + IS  +   I   G            
Sbjct: 1069 ELH-NMTVMEGEDATFKCVVSPEDAKLSWFKNGQHISSNEKFNISSNGLCHMLHIKNCQV 1127

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D   +    +   +  +L V+E    F + +     +E   A LEVE+++ETA+V W R
Sbjct: 1128 SDSCSLTAEAEGVISRALLQVQEAQVLFTKSMDPVVAEEFGEATLEVEVSTETAEVQWMR 1187

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
             G +I P  +K+   + G  R L I   ++ D G YSC    +   A+++V     +I  
Sbjct: 1188 QGVVIHPG-SKFTLRQSGRKRSLTIHKLTLLDRGTYSCETLHDRTQAKLSVEPRKIKIRK 1246

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             L + +  +   A+FE+EL+  +    W KDG  ++ +N +++T  G+   L I    LD
Sbjct: 1247 GLTDIQTIERETASFEVELSHSNVEGVWQKDGHVLKTNNRLRMTAQGRVHSLTISGLTLD 1306

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            D G Y   V N +  A L V+E  ++   +L + I  P  +   L  E+    +D+ W K
Sbjct: 1307 DTGTYIFSVDNVRSLARLDVKEIPVSILKKLDD-IRQPEGSGVTLECELSRHNIDIKWTK 1365

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
                ++  +   + S  +K  L I KC   D   Y C   DA  TT   V++ E   +I+
Sbjct: 1366 NGVQLKPGKNHRIYSMGRKCFLQILKCELGDSGLYVCDAGDA--TTSCSVDIYERELEIL 1423

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                +  I+   +   + +      P  EW  N + IK     K   ++    L I  V+
Sbjct: 1424 QSLEDLDIQEDQNAVFMCEVSLDDVPG-EWFKNGEKIKPTSTIKIRQEANKHFLLICNVK 1482

Query: 1352 NTDAGIYKLRLEN 1364
              D+G  K   +N
Sbjct: 1483 EEDSGEIKFVAKN 1495



 Score =  152 bits (369), Expect = 9e-35
 Identities = 142/660 (21%), Positives = 280/660 (42%), Gaps = 39/660 (5%)

Query: 629  LEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
            ++ +P  F KK +   +   E   + L   +  +  P I W  +G +++  +  +   + 
Sbjct: 879  VQDLPFKFIKKDEKTNISAYEEDSLTLRATVNRVNAP-IKWQ-RGRDLIRGDRFNTTSDG 936

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMI 745
            + H     L I  +K+   G YT      E   S+ +  +K+K  +        PL+++ 
Sbjct: 937  NTHY----LTINPLKRGDSGEYTCHLGTDEMHFSVHVKAMKVKFSK--------PLENIA 984

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802
              +G +V+L  ++  + +  + W K+++ + A      +++G   S+TI    +  D G 
Sbjct: 985  GLKGSNVVLKCELYKS-KGDVQWLKDSQEIAASRHFTIRAEGRVRSLTIHNITE-DDAGE 1042

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y  ++++      TSA + V  P         F+     +TV E G       V      
Sbjct: 1043 YACESKDER----TSATVMVNIPRIVE-----FVAELHNMTVME-GEDATFKCVVSPEDA 1092

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             ++W++N + IS +E    + +G    L I N        D   + + + G  S  A + 
Sbjct: 1093 KLSWFKNGQHISSNEKFNISSNGLCHMLHIKNCQVS----DSCSLTAEAEGVISR-ALLQ 1147

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
            +   +V F K +      E G+  +    ++ T   +W      I       + Q GR  
Sbjct: 1148 VQEAQVLFTKSMDPVVAEEFGEATLEVEVSTETAEVQWMRQGVVIHPGSKFTLRQSGRKR 1207

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G   C      T   L V+    +  + L D +  E++ A  EVE++ 
Sbjct: 1208 SLTIHKLTLLDRGTYSCETLHDRTQAKLSVEPRKIKIRKGLTDIQTIERETASFEVELSH 1267

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
               + VW++DG ++K   N+     +G +  L I   ++ D G Y   + +    A + V
Sbjct: 1268 SNVEGVWQKDGHVLKTN-NRLRMTAQGRVHSLTISGLTLDDTGTYIFSVDNVRSLARLDV 1326

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
             E+P  I+ +L + +  +G+  T E EL++ +  ++W K+G +++   + ++   G+K  
Sbjct: 1327 KEIPVSILKKLDDIRQPEGSGVTLECELSRHNIDIKWTKNGVQLKPGKNHRIYSMGRKCF 1386

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            L+I  C+L D+G Y C+ G++  +  + + E  +     L E + +  + +A    E+  
Sbjct: 1387 LQILKCELGDSGLYVCDAGDATTSCSVDIYERELEILQSL-EDLDIQEDQNAVFMCEVSL 1445

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            + +   W+K    I+ T    +  +  K  L+I    E+D  E   V  + +ST  L+VE
Sbjct: 1446 DDVPGEWFKNGEKIKPTSTIKIRQEANKHFLLICNVKEEDSGEIKFVAKNVESTAYLEVE 1505



 Score =  134 bits (325), Expect = 2e-29
 Identities = 147/742 (19%), Positives = 298/742 (40%), Gaps = 52/742 (7%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            T  +  + + ++ G    L+C  V+ P+  + W   G E++P + I +  E  +      
Sbjct: 65   TIDEVQRNKCIESGRPFKLQCE-VSDPDAQVWWYKDGNEVLPQDGIVIGSEEGIR----T 119

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L +   +    GTY      +  + ++   ++IK    +   + E  K+        ++L
Sbjct: 120  LSVQAAELCHSGTYRC----QMNDDAITFHVEIKAPSLKFIPISEVEKNKSTEVDSPIVL 175

Query: 755  SAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
              + + +    + WCK+ +   P   L  + D +T  I + +  K+ D G YT   +   
Sbjct: 176  KCE-LSDATSEVLWCKDGRELAPNPELNFQKDENTRKIKV-ESAKLSDTGNYTCHVQGD- 232

Query: 812  GIAETSAVITVEEPTEENA--EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
                 S  +  ++PT + +  +  + + +   + ++ +GT++ +  +  +     +   +
Sbjct: 233  ---TVSFKVDDQDPTAQVSWLKDGVELQQQSGLDIQSEGTMRKM--IIHSAELKHSGVYS 287

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             E +   + I    D     ++ + V  EI+    KC+ +        G  + +    VT
Sbjct: 288  CEAV--DDLIAFKVDVAAPPVMFSAV-PEIEKN--KCIEA--------GGPIILQSPPVT 334

Query: 930  FVKHLQKSYETE--EGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXX 986
            F    +        E   ++L CQ S + +T +WY +  E+    +  I  E        
Sbjct: 335  FAYIPEDDLHRNIVEQDNILLHCQVSRSDATAQWYKDGVELKSTSNVLIEVENDIRRLII 394

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE--KDVAILEVEINSET 1044
                  D G   C   D      + V+E     +   +D  +     +  +L  E++   
Sbjct: 395  LSAHLSDSGTYTCRAGDSALVFKVNVREPPVMIVYPKEDVHLDRHVPEEIVLSCELSRPN 454

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W +DG+ ++  +N    +  G  R+L I ++ + D GEY C   D+S    + + E
Sbjct: 455  GKVTWFKDGQKLQESEN-IKLKTEGPYRRLKILHSGIEDSGEYVCDTADDSIFFNLNIKE 513

Query: 1105 LPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
             P  I++  Q+Q         +     E+++ +A VRW++DG E++ S+ + L +DG  +
Sbjct: 514  PPVRIVSPSQSQMELCQQTSERMVLSCEISRPNATVRWYRDGLEVEESDSLILEVDGVYR 573

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVE 1219
            +L I    + D+ EY C+  +   T  + + EP + F    ++   +         L  E
Sbjct: 574  RLIIPKPTVKDSAEYVCDTTDDSVTFFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVLECE 633

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +     +V+W K    IE+    T+  D   R L I     +D  +Y C   DA+     
Sbjct: 634  VCRPNAEVSWKKDGDEIEENSNVTITEDGTNRQLTIHSADFEDAGQYVC---DARDDVMD 690

Query: 1280 KVEVVEFPPKIVDYEREYRIKRG---SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             +  ++ PP  +  + +   KR    SD  +L    +       W+ +++ I   +H   
Sbjct: 691  FLVKIKDPPLKILRKADIETKRQFMVSDAIVLKCEISRANGVVNWLKDNEKIDGNEHFTC 750

Query: 1337 SIDSKSASLTIKKVENTDAGIY 1358
              +    SL +   E  D+G Y
Sbjct: 751  EEEGAFRSLIVLNAELRDSGEY 772



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 161/864 (18%), Positives = 325/864 (37%), Gaps = 80/864 (9%)

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + WY+  E +   +TITQ+ +     LV T+  S  +       AS +       A V +
Sbjct: 4    VCWYKEVEELPQCDTITQSEETIGA-LVKTDEPSHSEES-----ASETDDVPVQFA-VDL 56

Query: 924  DVEKVTF--VKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980
                V F  +  +Q++   E G+   L+C+ S       WY +  E+   D   I  E  
Sbjct: 57   PAPPVMFSTIDEVQRNKCIESGRPFKLQCEVSDPDAQVWWYKDGNEVLPQDGIVIGSEEG 116

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV---AILE 1037
                          G  +C + D   +  + +K    +FI   +  + K  +V    +L+
Sbjct: 117  IRTLSVQAAELCHSGTYRCQMNDDAITFHVEIKAPSLKFIPISEVEKNKSTEVDSPIVLK 176

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
             E++  T++V+W +DG  + P   + +F+K  + RK+ + +  + D G Y+C ++ ++ +
Sbjct: 177  CELSDATSEVLWCKDGRELAPNP-ELNFQKDENTRKIKVESAKLSDTGNYTCHVQGDTVS 235

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157
             +V   +   ++       ++ + +    + E T    ++      +E++ S        
Sbjct: 236  FKVDDQDPTAQVSWLKDGVELQQQSGLDIQSEGTMRKMIIH----SAELKHSGVYSCEAV 291

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI---LTVEEPSINFTLRLPEFIL---VPAN 1211
                  K+             E+  +KC      + ++ P + F   +PE  L   +   
Sbjct: 292  DDLIAFKVDVAAPPVMFSAVPEIEKNKCIEAGGPIILQSPPVTFAY-IPEDDLHRNIVEQ 350

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
             +  L  ++        WYK    ++ T    +  +   R LII      D   YTC   
Sbjct: 351  DNILLHCQVSRSDATAQWYKDGVELKSTSNVLIEVENDIRRLIILSAHLSDSGTYTCRAG 410

Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIK 1329
            D  S    KV V E P  IV  + +  + R     +++  +   +PN +  W  + + ++
Sbjct: 411  D--SALVFKVNVREPPVMIVYPKEDVHLDRHVPEEIVLSCE-LSRPNGKVTWFKDGQKLQ 467

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
            + ++ K   +     L I      D+G Y       C  AD  +    L+   PP +  I
Sbjct: 468  ESENIKLKTEGPYRRLKILHSGIEDSGEYV------CDTADDSIFFN-LNIKEPPVR--I 518

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
            +    S + +C    + T    ++   +      T  W     +   ++    L+ +  Y
Sbjct: 519  VSPSQSQMELC----QQTSERMVLSCEISRPNA-TVRWYR-DGLEVEESDSLILEVDGVY 572

Query: 1450 RFRAYAVNEVDISDASE----TTE----YYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
              R   + +  + D++E    TT+    ++  I E  ++     K    +     E + L
Sbjct: 573  --RRLIIPKPTVKDSAEYVCDTTDDSVTFFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVL 630

Query: 1502 TCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
             C     P  +V+W +DG +++     T      NR               Y C A +D 
Sbjct: 631  ECEVCR-PNAEVSWKKDGDEIEENSNVTITEDGTNR-QLTIHSADFEDAGQYVCDARDD- 687

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
                   +V I+  P+  +   DI+ K +  V D  ++   I       V W K+  K++
Sbjct: 688  ---VMDFLVKIKDPPLKILRKADIETKRQFMVSDAIVLKCEISR-ANGVVNWLKDNEKID 743

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSKPEG 1671
             ++ +    +     + +   +   S +Y  +A +     SV   E  + +     KP+ 
Sbjct: 744  GNEHFTCEEEGAFRSLIVLNAELRDSGEYICDAQDDKVVFSVTVEEAPVSIVGNTQKPKH 803

Query: 1672 PVIMR--------EISRESVTIEW 1687
             +++         E+SR +  ++W
Sbjct: 804  CILLTGDELSLECEVSRVNAVVQW 827



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 4/105 (3%)

Query: 1555 DHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            D G+  TSC V I ++ + I  S ED+  +      ++    ++ +P     W+KNG K+
Sbjct: 1403 DAGDATTSCSVDIYERELEILQSLEDLDIQEDQNAVFMCEVSLDDVPGE---WFKNGEKI 1459

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            +      I  +     + I  +K   S +    A N   T+ +EV
Sbjct: 1460 KPTSTIKIRQEANKHFLLICNVKEEDSGEIKFVAKNVESTAYLEV 1504


>UniRef50_Q7YRF6 Cluster: Cardiac titin; n=4; Eutheria|Rep: Cardiac
            titin - Canis familiaris (Dog)
          Length = 2200

 Score =  193 bits (471), Expect = 4e-47
 Identities = 192/739 (25%), Positives = 322/739 (43%), Gaps = 44/739 (5%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIE 685
            ++E I     K  + Q+V      +  C ++A   P+I W FKG + +P E  + +  + 
Sbjct: 1444 VVEVIRDWLVKPIRDQHVKPKGTAVFTC-VIAKDTPNIKW-FKGYDEIPLEPNDKTEIVR 1501

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
               H++   LK+ N        +   AV  EG+       K+  GE+E  ++++P++ + 
Sbjct: 1502 EGNHLF---LKVKNATPEDIDEH---AVEIEGKR---YPAKLTLGEREV-ELLKPIEDVT 1551

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGV 802
            + + ES    A++     P   W    + ++  PT   K++G    +T+ K K +   G 
Sbjct: 1552 IYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLHKVK-LDQAGE 1609

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
               +A N    A T+A++TV+E   + A P       +++TV E+   +    +TR    
Sbjct: 1610 VLYQALN----AFTTAILTVKEIELDFAVP------LKDVTVPERRQARFECVLTREA-- 1657

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            ++ W +  +II  S+      DG+   LVI   DS  D  D     +   GK S  AR+ 
Sbjct: 1658 NVIWSKGPDIIKASDKFDIIADGKKHILVIN--DSHFD--DEGVYTAEVEGKKS-SARLF 1712

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
            +   ++ F+  L+     +EG+T    C+ SH  +   W+ N  ++       I  EG+ 
Sbjct: 1713 VTGIRLKFISPLEDQ-TVKEGQTATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKT 1771

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D+  I+  VKD  +S  L V E  P F  KL D    EKD  IL+ E+ 
Sbjct: 1772 HKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDEIILKCEV- 1830

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
            S+   V W +DGE I P   KY  +  G  R L I+   + D+GEY C    +   A VT
Sbjct: 1831 SKDVPVKWFKDGEEIVPSA-KYSIKTDGLRRILKIKKAELKDKGEYMCDCGTDQTKANVT 1889

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V     ++   L   ++  G  A FEIEL++ D   +W   G  +  S   ++  DGKK 
Sbjct: 1890 VEARLIKVEKPLYGVELFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKH 1949

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
             L +Y+C LD  GE S +  N+K  A L V+E  + F   L + + V    +A    E+ 
Sbjct: 1950 ILVLYNCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVS 2008

Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
             E     W K    I   +K  LI D  K +L+I+    +D+ +Y     D  ++ KL +
Sbjct: 2009 REPKTFRWLKGTQEITGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLII 2068

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            E +    K +   ++   K        V+  +      +W  N + +   +      + K
Sbjct: 2069 EGIRL--KFLTPLKDVTAKERESAVFTVEL-SHDNIRVKWFKNDQRLHTSRSVWMDDEGK 2125

Query: 1342 SASLTIKKVENTDAGIYKL 1360
            + S+T + +   D    K+
Sbjct: 2126 THSITFRDLSIDDTSQIKV 2144



 Score =  148 bits (359), Expect = 1e-33
 Identities = 163/655 (24%), Positives = 298/655 (45%), Gaps = 46/655 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVA 683
            L+ +P  F K+ K   + E    GS  + EC LV+      +W+  G  I    ++  +A
Sbjct: 1254 LKAVPLKFVKEIKDIVLTEAEPVGSSAIFEC-LVSPSTAITSWMKDGSSIRESPKHRFIA 1312

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741
               D  ++     I +V+    G YT V    N+E  ++  +V+     E+ P + ++ L
Sbjct: 1313 DGKDRKLH-----IMDVQLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTL 1362

Query: 742  KSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796
            +  + V +G+ + LS ++  N    + W K+ K V   P K      G   ++TI     
Sbjct: 1363 EEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGKIVPGVIGLLRALTI-NDAD 1419

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             +D G YT+  EN+  +  +S V  VE   +   +P       ++  VK KGT      +
Sbjct: 1420 DQDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP------IRDQHVKPKGTAVFTCVI 1473

Query: 857  TRNPVPSITWYRN-NEI-ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             ++  P+I W++  +EI + P++      +G ++ L + N   E D  ++   A    GK
Sbjct: 1474 AKD-TPNIKWFKGYDEIPLEPNDKTEIVREGNHLFLKVKNATPE-DIDEH---AVEIEGK 1528

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973
              + A++T+   +V  +K ++      E ++   + + S   +  +W    + +      
Sbjct: 1529 -RYPAKLTLGEREVELLKPIE-DVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTC 1586

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
            EI  EG               G +     +  T+ +L VKE   +F   L+D  V E+  
Sbjct: 1587 EIKAEGGKRFLTLHKVKLDQAGEVLYQALNAFTTAILTVKEIELDFAVPLKDVTVPERRQ 1646

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            A  E  +  E A+V+W +  +IIK   +K+D    G    L I ++   DEG Y+  +  
Sbjct: 1647 ARFECVLTRE-ANVIWSKGPDIIK-ASDKFDIIADGKKHILVINDSHFDDEGVYTAEVEG 1704

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
            +  +A + V  +  + I+ L++Q V +G  ATF  EL+     V WFK+ +++  S  + 
Sbjct: 1705 KKSSARLFVTGIRLKFISPLEDQTVKEGQTATFVCELSHEKMHVVWFKNDAKLHTSRTVL 1764

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
            ++ +GK  KL+I +  LDD  +   +V +   +A L V E    FT++L +   V  + +
Sbjct: 1765 ISSEGKTHKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKD-E 1823

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
              L  E+  + + V W+K    I  + K+++ +D  +R L I+K    D+ EY C
Sbjct: 1824 IILKCEV-SKDVPVKWFKDGEEIVPSAKYSIKTDGLRRILKIKKAELKDKGEYMC 1877



 Score =  145 bits (352), Expect = 1e-32
 Identities = 123/553 (22%), Positives = 251/553 (45%), Gaps = 15/553 (2%)

Query: 830  AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886
            A P  F+   ++I + E   +    +     +P  +IT W ++   I  S       DG+
Sbjct: 1256 AVPLKFVKEIKDIVLTEAEPVGSSAIFECLVSPSTAITSWMKDGSSIRESPKHRFIADGK 1315

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            + +L I +V    D+G+Y CV      + +  A++ ++   V FVK L++     +G+ +
Sbjct: 1316 DRKLHIMDVQLS-DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPL 1374

Query: 947  ILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDVGVIKCIVKDQ- 1004
             L C+ +      W  + K +     + +    G             D G     V++  
Sbjct: 1375 YLSCELNKERDVVWRKDGKIVVEKPGKIVPGVIGLLRALTINDADDQDAGTYTVTVENAN 1434

Query: 1005 --ETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSETADVVWERD-GEIIKPKK 1060
              E S+ + V E I ++ ++ ++D  VK K  A+    I  +T ++ W +   EI     
Sbjct: 1435 NLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAVFTCVIAKDTPNIKWFKGYDEIPLEPN 1494

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
            +K +  + G+   L ++N +  D  E++  +  +   A++T+ E   E++  +++  + +
Sbjct: 1495 DKTEIVREGNHLFLKVKNATPEDIDEHAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYE 1554

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
               A+F+ E+++ D   +W   G  ++ S   ++  +G K+ L ++   LD AGE   + 
Sbjct: 1555 KESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQA 1614

Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
             N+  TAILTV+E  ++F + L + + VP    A     +  E  +V W K   +I+ ++
Sbjct: 1615 LNAFTTAILTVKEIELDFAVPLKD-VTVPERRQARFECVLTREA-NVIWSKGPDIIKASD 1672

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300
            KF +I+D KK  L+I     DD+  YT  +   KS+ +L V  +    K +    +  +K
Sbjct: 1673 KFDIIADGKKHILVINDSHFDDEGVYTAEVEGKKSSARLFVTGIRL--KFISPLEDQTVK 1730

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
             G   T + +  +  + +  W  N   +   +    S + K+  L I++V   D    + 
Sbjct: 1731 EGQTATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEIREVTLDDISQIRA 1789

Query: 1361 RLENNCGHADVEM 1373
            ++++    A++++
Sbjct: 1790 QVKDLSSSANLKV 1802



 Score =  138 bits (333), Expect = 2e-30
 Identities = 152/643 (23%), Positives = 254/643 (39%), Gaps = 44/643 (6%)

Query: 660  IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            I E DI   W  KGE + P     +  E         L +  VK  Q G     A+N   
Sbjct: 1564 ISEADIPGQWKLKGELLRPSPTCEIKAEGGKRF----LTLHKVKLDQAGEVLYQALN--- 1616

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             A    +L +K  E +      PLK + V +        + V      + W K    +KA
Sbjct: 1617 -AFTTAILTVKEIELD---FAVPLKDVTVPERRQARF--ECVLTREANVIWSKGPDIIKA 1670

Query: 778  ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
                   +DG  H I ++      DEGVYT + E  +    +SA + V     +      
Sbjct: 1671 SDKFDIIADGKKH-ILVINDSHFDDEGVYTAEVEGKK----SSARLFVTGIRLK------ 1719

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            FI+  ++ TVKE  T   V  ++   +  + W++N+  +  S T+  + +G+  +L I  
Sbjct: 1720 FISPLEDQTVKEGQTATFVCELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEIR- 1777

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK-HLQKSYETEEGKTVILECQTS 953
               E+   D   + +     SS      ++ +    VK H +   E +E   +IL+C+ S
Sbjct: 1778 ---EVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDE---IILKCEVS 1831

Query: 954  HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013
              V  KW+ + +EI       I  +G             D G   C     +T   + V+
Sbjct: 1832 KDVPVKWFKDGEEIVPSAKYSIKTDGLRRILKIKKAELKDKGEYMCDCGTDQTKANVTVE 1891

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK-RGHIR 1072
              + +  + L   E+   + A  E+E++       W+  GE +    +    E  + HI 
Sbjct: 1892 ARLIKVEKPLYGVELFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHIL 1951

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132
             LY  N  +   GE S    +    A + V ELP   IT L + KV + ++A FE E+++
Sbjct: 1952 VLY--NCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSR 2009

Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
                 RW K   EI   + ++L  DG K  L I     +D G+Y  E  +   +  L +E
Sbjct: 2010 EPKTFRWLKGTQEITGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLIIE 2069

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
               + F   L + +       A  TVE+  + + V W+K    +  +    +  + K  +
Sbjct: 2070 GIRLKFLTPLKD-VTAKERESAVFTVELSHDNIRVKWFKNDQRLHTSRSVWMDDEGKTHS 2128

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDY 1293
            +  R  + DD  +     +   S  KL     +  F  K+ DY
Sbjct: 2129 ITFRDLSIDDTSQIKVEAMGLSSEAKLTALEGDPYFTGKLQDY 2171



 Score =  134 bits (325), Expect = 2e-29
 Identities = 140/592 (23%), Positives = 249/592 (42%), Gaps = 41/592 (6%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVKKF 703
            V E      EC L    E ++ W  KG +I+   +   +  +   H    +L I +    
Sbjct: 1641 VPERRQARFECVLTR--EANVIWS-KGPDIIKASDKFDIIADGKKH----ILVINDSHFD 1693

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             EG YT     ++  A L +     TG +   + I PL+   V++G++     ++  + +
Sbjct: 1694 DEGVYTAEVEGKKSSARLFV-----TGIRL--KFISPLEDQTVKEGQTATFVCEL-SHEK 1745

Query: 764  PTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
              + W KN+  +    T    S+G TH + I   ++V  + +  ++A+  +    +SA +
Sbjct: 1746 MHVVWFKNDAKLHTSRTVLISSEGKTHKLEI---REVTLDDISQIRAQVKD--LSSSANL 1800

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
             V E        P F  +  + T  EK  I L   V+++ VP + W+++ E I PS   +
Sbjct: 1801 KVLEAD------PYFTVKLHDKTGVEKDEIILKCEVSKD-VP-VKWFKDGEEIVPSAKYS 1852

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
               DG    L I   + + D G+Y C      G     A VT++   +   K L    E 
Sbjct: 1853 IKTDGLRRILKIKKAELK-DKGEYMC----DCGTDQTKANVTVEARLIKVEKPLY-GVEL 1906

Query: 941  EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
              G+T   E + S   V  +W    + ++     EII++G+              G +  
Sbjct: 1907 FVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCQLDMTGEVSF 1966

Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
               + +++  L VKE    FI  L D +V EKD A  E E++ E     W +  + I   
Sbjct: 1967 QAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGD 2026

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
             +K +  K G    L I++ +  DEG+Y     D+  + ++ +  +  + +T L++    
Sbjct: 2027 -DKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAK 2085

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            +   A F +EL+  +  V+WFK+   +  S  + +  +GK   +   D  +DD  +   E
Sbjct: 2086 ERESAVFTVELSHDNIRVKWFKNDQRLHTSRSVWMDDEGKTHSITFRDLSIDDTSQIKVE 2145

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
                   A LT  E    FT +L ++  V  + +  L  EI      V W++
Sbjct: 2146 AMGLSSEAKLTALEGDPYFTGKLQDYTGVEKD-EVILQCEISKADAPVKWFQ 2196



 Score =  101 bits (241), Expect = 3e-19
 Identities = 119/521 (22%), Positives = 220/521 (42%), Gaps = 41/521 (7%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            GI   F    + Q V EG      C L +  +  + W     ++     + ++ E   H 
Sbjct: 1715 GIRLKFISPLEDQTVKEGQTATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHK 1773

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                       + +E T   ++  R     L     +K  E +P   ++      V + E
Sbjct: 1774 L----------EIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDE 1823

Query: 751  SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             +IL  +V  +    + W K+ +   P      K+DG    I  +K  ++KD+G Y    
Sbjct: 1824 -IILKCEV--SKDVPVKWFKDGEEIVPSAKYSIKTDG-LRRILKIKKAELKDKGEYMCDC 1879

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
                G  +T A +TVE    +  E PL+     E+ V E  T +    ++   V    W 
Sbjct: 1880 ----GTDQTKANVTVEARLIK-VEKPLY---GVELFVGE--TARFEIELSEPDVHG-QWK 1928

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
               E ++ S       DG+   LV+ N   ++ +G+    A+N+  KS+  A + +    
Sbjct: 1929 LKGEPLTASPDCEIIEDGKKHILVLYNCQLDM-TGEVSFQAANA--KSA--ANLKVKELP 1983

Query: 928  VTFVKHLQ--KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984
            + F+  L   K +E +E K    EC+ S    T +W    +EI+G D  E+I++G     
Sbjct: 1984 LIFITPLSDVKVFEKDEAK---FECEVSREPKTFRWLKGTQEITGDDKVELIKDGTKHSL 2040

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G      +D+ TS  L+++    +F+  L+D   KE++ A+  VE++ + 
Sbjct: 2041 VIKSAAFEDEGKYIFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKERESAVFTVELSHDN 2100

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W ++ + +   ++ +  +  G    +  R+ S+ D  +        S  A++T +E
Sbjct: 2101 IRVKWFKNDQRLHTSRSVW-MDDEGKTHSITFRDLSIDDTSQIKVEAMGLSSEAKLTALE 2159

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145
              P    +LQ+    + ++   + E++K DA V+WF+DG+E
Sbjct: 2160 GDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFQDGNE 2200



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 84/288 (29%), Positives = 123/288 (42%), Gaps = 13/288 (4%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
            G+ A FE  ++   A+  W KDGS I+ S   +   DGK +KL I D  L DAGEY+C  
Sbjct: 1277 GSSAIFECLVSPSTAITSWMKDGSSIRESPKHRFIADGKDRKLHIMDVQLSDAGEYTCVL 1336

Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSV 1235
             +GN +   TA L VEE  + F   L E + V      YL+ E+  E  DV W K  K V
Sbjct: 1337 RLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIV 1395

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVE-FPPKIVDY 1293
            +E   K         R L I    + D   YT  + +A +      V+VVE     +V  
Sbjct: 1396 VEKPGKIVPGVIGLLRALTINDADDQDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP 1455

Query: 1294 EREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKV 1350
             R+  +K +G+ V   V   A   PN +W      I    + K  I  +     L +K  
Sbjct: 1456 IRDQHVKPKGTAVFTCV--IAKDTPNIKWFKGYDEIPLEPNDKTEIVREGNHLFLKVKNA 1513

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
               D   + + +E     A + +    ++   P     I E +S+S +
Sbjct: 1514 TPEDIDEHAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFD 1561



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 29/236 (12%)

Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-----DGD 785
           E   P  I+ + +  +  G+   LS  V G P+P I W    K V   P+       DG+
Sbjct: 94  EGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFF--KGVMLTPSADYKFVFDGN 151

Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-----------EPTEENAE--- 831
            HS+ IL  K  +DEG YT  A N  G A  SA + +            EP E   E   
Sbjct: 152 DHSLIILFTK-FEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFE 210

Query: 832 ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGE 886
              PP F+  F+ I             V   P P++TW++ ++ +  +   TI  N DG 
Sbjct: 211 GPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGS 270

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
              +V  N     DSG Y C A N  G+S+  A + + +E       L+K+  T E
Sbjct: 271 GTFIV--NDPQREDSGLYVCRAENMWGESTCTAELLVLLEDTDMTDALRKAKPTPE 324



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 59/216 (27%), Positives = 89/216 (41%), Gaps = 27/216 (12%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           EG  P F K+     +  G    L   +  IP+P I W FKG  + P  +     + + H
Sbjct: 94  EGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDH 153

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT---GEKE------------- 733
                L I   K   EG YT VA N  G+A     LKI +   G+KE             
Sbjct: 154 S----LIILFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKF 209

Query: 734 ----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDT 786
               PP  ++  K +   +G   +    V+G P PT+TW K +K +      +   + D 
Sbjct: 210 EGPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDG 269

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
               I+   + +D G+Y  +AEN  G +  +A + V
Sbjct: 270 SGTFIVNDPQREDSGLYVCRAENMWGESTCTAELLV 305



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 48/219 (21%), Positives = 96/219 (43%), Gaps = 12/219 (5%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+++   P+F++++       G   +    V G P+P+I WF +  ++ PS D++  +D 
Sbjct: 91  SKKEGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDG 150

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
           ++ + +++   F ED G +TCVA N  G A  +  L + +     G + T          
Sbjct: 151 NDHSLIILFTKF-EDEGEYTCVASNEYGQAVCSASLKISS--KGEGQKET-----EAEPV 202

Query: 623 XXXADILEG-IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
               +  EG  PP F K+ K  +   G   + E  ++  P P + W  + +++  +   +
Sbjct: 203 ETFLEKFEGPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHT 262

Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
           +    D         + + ++   G Y   A N  GE++
Sbjct: 263 IIHNPD---GSGTFIVNDPQREDSGLYVCRAENMWGEST 298



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 61/206 (29%), Positives = 96/206 (46%), Gaps = 15/206 (7%)

Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII-KPKKNKYDFEKRGH 1070
            V E  P  +  L D   +E DV  L   I +   +V W  +G+++   +K K   ++  +
Sbjct: 879  VGEDGPVMLTPLVDTTAEEGDVVNLTSSITN-AKEVNWYFEGKLVHSDEKFKCLQDQNTY 937

Query: 1071 IRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVE-LPPEIITRLQNQKVNKGNKAT 1125
               ++  NT  H +G Y+C       + S +A++TVV+   P I  R++  +V  G+ A 
Sbjct: 938  TLVIHGVNTEEH-QGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAK 996

Query: 1126 FEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EV 1180
            F  E+    +   +WFK G EI  S+   +        L+I    + D GEY+C    E 
Sbjct: 997  FTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEY 1056

Query: 1181 GNSKCTAILTVEEPSINFTLR--LPE 1204
            G+  CTA LTV  P     +R  LPE
Sbjct: 1057 GSVSCTATLTVTVPGAEKKVRKLLPE 1082



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 27/91 (29%), Positives = 49/91 (53%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++ +P H   G    FE  V G P P +TWF+++  +  +    + ++ D   T +
Sbjct: 215 PYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGSGTFI 274

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           + +   ED+G + C A+N  G ++ T EL+V
Sbjct: 275 VNDPQREDSGLYVCRAENMWGESTCTAELLV 305



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 15/199 (7%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHS 788
            ++ P ++ PL      +G+ V L++ +       + W    K V +        D +T++
Sbjct: 881  EDGPVMLTPLVDTTAEEGDVVNLTSSITNAKE--VNWYFEGKLVHSDEKFKCLQDQNTYT 938

Query: 789  ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            + I      + +G YT +A N++G A TSA +TV +        P+   R + + V    
Sbjct: 939  LVIHGVNTEEHQGAYTCEALNAKGNASTSAKLTVVK-----RAAPVIKRRIEPLEVALGH 993

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKC 906
              K    V   P     W++    I  S+  +I  +     +E++ T V   +D G+Y C
Sbjct: 994  LAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQV---VDCGEYTC 1050

Query: 907  VASNSAGKSSHGARVTIDV 925
             ASN  G  S  A +T+ V
Sbjct: 1051 KASNEYGSVSCTATLTVTV 1069



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 7/232 (3%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P+ +    + T +E   + L + +T      + WY   +++   E      D     LVI
Sbjct: 884  PVMLTPLVDTTAEEGDVVNLTSSITN--AKEVNWYFEGKLVHSDEKFKCLQDQNTYTLVI 941

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC-- 950
              V++E   G Y C A N+ G +S  A++T+       +K   +  E   G      C  
Sbjct: 942  HGVNTEEHQGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEV 1001

Query: 951  QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETST 1008
            Q +  V  +W+   +EI   D   I                 D G   C   ++    S 
Sbjct: 1002 QIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEYGSVSC 1061

Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
               +  T+P   +K++    + K     EV + S       E + + ++PKK
Sbjct: 1062 TATLTVTVPGAEKKVRKLLPEPKPQPKEEVVLKSVLRKRPEEEEPK-VEPKK 1112



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 9/168 (5%)

Query: 664  DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
            ++ W F+G+ +  DE        D + Y  V+   N ++ Q G YT  A+N +G AS   
Sbjct: 912  EVNWYFEGKLVHSDEKFKCL--QDQNTYTLVIHGVNTEEHQ-GAYTCEALNAKGNASTSA 968

Query: 724  VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPT 780
              K+   ++  P +   ++ + V  G     + +V   P     W K  + +        
Sbjct: 969  --KLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSI 1026

Query: 781  KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            +S     ++ IL+ + V D G YT KA N  G    +A +TV  P  E
Sbjct: 1027 RSSKYVSTLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTVPGAE 1073



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 1/98 (1%)

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
           +++    P+FI       +      KL   VT  P P I W+    +++PS      FDG
Sbjct: 91  SKKEGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDG 150

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +  L+I     E D G+Y CVASN  G++   A + I
Sbjct: 151 NDHSLIILFTKFE-DEGEYTCVASNEYGQAVCSASLKI 187



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 4/156 (2%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAK--STTKLKVE 1282
            +V WY +  ++   EKF  + D    TL+I    TE+ Q  YTC  L+AK  ++T  K+ 
Sbjct: 912  EVNWYFEGKLVHSDEKFKCLQDQNTYTLVIHGVNTEEHQGAYTCEALNAKGNASTSAKLT 971

Query: 1283 VVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            VV+    ++    E   +  G       + Q  P    +W    + I +           
Sbjct: 972  VVKRAAPVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKY 1031

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             ++L I + +  D G Y  +  N  G       +T+
Sbjct: 1032 VSTLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1067



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 1/95 (1%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+   ++ P     G   +F C+V+  P  +  WF+    I  S    +      V+TL
Sbjct: 977  APVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIR-SSKYVSTL 1035

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             I      D G +TC A N  G  S T  L V  P
Sbjct: 1036 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 1070



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 40/186 (21%), Positives = 69/186 (37%), Gaps = 7/186 (3%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXX 1538
            P +  PL + T E  + + LT       +  V WY +GK + +    K   +        
Sbjct: 884  PVMLTPLVDTTAEEGDVVNLTSSITNAKE--VNWYFEGKLVHSDEKFKCLQDQNTYTLVI 941

Query: 1539 XXXXXXXX--XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y C A N  G   TS  + + ++    I       +  +G     T  +
Sbjct: 942  HGVNTEEHQGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEV 1001

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            +  P     W+K G ++    + +I + +  S + I   +     +YT +ASN  G+ S 
Sbjct: 1002 QIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEYGSVSC 1061

Query: 1657 EVTLKV 1662
              TL V
Sbjct: 1062 TATLTV 1067



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 57/213 (26%), Positives = 87/213 (40%), Gaps = 41/213 (19%)

Query: 1016 IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
            +P FI+++ + E+   DVA L V +       + W   G ++ P  + Y F   G+   L
Sbjct: 97   VPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSAD-YKFVFDGNDHSL 155

Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTV--------------VE---------LPP 1107
             I  T   DEGEY+C+  +E     C+A + +              VE          PP
Sbjct: 156  IILFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFEGPCPP 215

Query: 1108 EIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTI----DGKKQK 1162
              +   +     +G  A FE + L +    V WFK+    Q   ++  TI    DG    
Sbjct: 216  YFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESK--QLCTNVYHTIIHNPDGSGTF 273

Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTV 1191
            + + D   +D+G Y C      G S CTA L V
Sbjct: 274  I-VNDPQREDSGLYVCRAENMWGESTCTAELLV 305



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 496  PVFEKPTSEEQSMAPI-FVEKLRP----KHTPDGSTVQFECQVEGYPRPQIT-WFRQTAI 549
            P  E P + +    P+ FV++++     +  P GS+  FEC V   P   IT W +  + 
Sbjct: 1244 PPDEAPFTYQLKAVPLKFVKEIKDIVLTEAEPVGSSAIFECLVS--PSTAITSWMKDGSS 1301

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            I+ S   +   D  +   L I +V   DAG +TCV +      +ST +L+VE
Sbjct: 1302 IRESPKHRFIADGKD-RKLHIMDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 1352



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 22/92 (23%), Positives = 52/92 (56%), Gaps = 9/92 (9%)

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV----- 1658
            V+W+KN  KL   +   I+++ KT  + I+E+     S+   +  + + +++++V     
Sbjct: 1748 VVWFKNDAKLHTSRTVLISSEGKTHKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADP 1807

Query: 1659 --TLKVYDKPSKPEGPVIMR-EISRESVTIEW 1687
              T+K++DK    +  +I++ E+S++ V ++W
Sbjct: 1808 YFTVKLHDKTGVEKDEIILKCEVSKD-VPVKW 1838



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%)

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
            +SN +I     +GD   ++  + GIP P++ W+  G  L    +Y          + I  
Sbjct: 104  VSNAEIS----IGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDHSLIILF 159

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
             K     +YT  ASN  G +    +LK+  K
Sbjct: 160  TKFEDEGEYTCVASNEYGQAVCSASLKISSK 190



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 18/31 (58%), Positives = 20/31 (64%)

Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           PED GT+T VA NA G  SST  L + AP S
Sbjct: 1   PEDEGTYTFVANNAMGQVSSTANLRLAAPES 31


>UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG33519-PB
            - Drosophila melanogaster (Fruit fly)
          Length = 4129

 Score =  193 bits (471), Expect = 4e-47
 Identities = 308/1315 (23%), Positives = 525/1315 (39%), Gaps = 158/1315 (12%)

Query: 538  RPQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596
            +P   W R      P + F++ + +D++   LV + V PEDAG +TCVA+ + G  S + 
Sbjct: 1147 KPVFQWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSA 1206

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            EL V+      G+  T+                E   PT   + +      G   +LE +
Sbjct: 1207 ELSVQ------GAIQTLNR--------------EPEKPTLVIEHREANASIGGSAILELQ 1246

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
                P+P + W   GE I  D+      E +  M    L I NV     G YT+ A+N  
Sbjct: 1247 CKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS---LVIKNVDTVDAGVYTIEAINEL 1303

Query: 717  GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
            G+    I L +K     PP+ I+ +  +    GE++ +  +V G P+PT+    N K V 
Sbjct: 1304 GQDESSINLVVKA----PPK-IKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVT 1358

Query: 777  A-----LPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            A     + + S G +    +++ K++K    G Y++KA N   +++TS   +    ++  
Sbjct: 1359 AESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATND--LSQTSEYWSCTVKSK-- 1414

Query: 830  AEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGEN 887
               P+ +  F+ E    EK  +++  R+   P   +TWY +  EI       T + DG  
Sbjct: 1415 ---PVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNA 1471

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT-- 945
              L IT   + +D+G Y   A+N  G ++   ++ I  +      H  K+    EG +  
Sbjct: 1472 YTLKITGA-TRVDAGKYTVKATNEHGSATSSTQLLI--KCAPEFTHKLKNITVAEGDSNV 1528

Query: 946  -VILECQTSHTVSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXXXXDVGVIKC-IV 1001
             +++          KWY +  EI     D R  ++EG               G   C I+
Sbjct: 1529 ELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRH-VEEGNDFKLIMNQVATNMQGNYTCKIM 1587

Query: 1002 KD--QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDG-EIIK 1057
             D  +     +V     P+  R L++ EV+E     LEVE+ SE  A + W +DG EI +
Sbjct: 1588 NDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYE 1647

Query: 1058 PKKNKYDFE-KRGHIRKLYIRNTSVHDEGEY-------------SC---ILRDESCTAEV 1100
              + K   + +R     L +      D G Y             +C   +L  E+ + E 
Sbjct: 1648 DARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQ 1707

Query: 1101 TV-------VELP-----PEII-TRLQNQKVNKGNKATFEIELT---KGDALVRWFKDGS 1144
            TV        E P     PEI+   +  Q   +     +E+  T   K +A+  W+ DG 
Sbjct: 1708 TVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAI--WYHDGK 1765

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204
             I    H  +T+DG   KL++   DL DAGEY   V N K        E S++      +
Sbjct: 1766 PITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQN-KVGEKSHQGELSLSGIAEYRK 1824

Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKS-----VIEDTEKFTLISDVKKRTLIIRKCT 1259
             IL        + V   D+  +   +         +++D +     ++VK +  + +K  
Sbjct: 1825 PILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLK--VDKKDA 1882

Query: 1260 EDDQCEYTCVL--LDA--KSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVD 1310
            E+   +YTC L  L+A  K + + +++V     ++V     D   +  I   +D   L  
Sbjct: 1883 ENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEISGLNDTKCLPG 1942

Query: 1311 --------YQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKSASLTIKKVENTDAGIY 1358
                     QA P+P   W   ++ +  C H        +D+    L  + V   + G Y
Sbjct: 1943 DTICFEALVQANPKPKVSWTRGNENL--CNHENCEVIADVDADKYRLVFQSVSPCEDGKY 2000

Query: 1359 KLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDS----SSINICWDEPENTGNSTII 1413
             +   N+ G A V+ N+ +L +KP+   +P    I      S+  +    P  T      
Sbjct: 2001 TITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKD 2060

Query: 1414 YYVVEYQEIDT--TEWISVKNITKTQT-------SIQNLKTNSSYRFRAYAVNEVDISDA 1464
               + Y+ I+    + +  K  TK  T        I++ + N    +   A NE+ ++ A
Sbjct: 2061 DKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKA 2120

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
                  +K+   +   +P+  K L N +     E + L C   G P P V W +DG ++K
Sbjct: 2121 P-----FKLAMLS--LAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVK 2173

Query: 1524 TAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
             +++       +                 YK I  N HGE    C V ++ + +     +
Sbjct: 2174 PSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLK 2233

Query: 1579 DI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELK 1636
             I  Q   VG+   + A + G P PEV WYK+G  L    E N        + + I   +
Sbjct: 2234 PITSQTVVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQ 2293

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEWKPPLDDGG 1695
               +  Y    +N  G       +++  K SKP     +++ S  E   ++    +    
Sbjct: 2294 PLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNP 2353

Query: 1696 LELTKYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                ++    HE  PD +  I + +   +  +  I+K       ++ VIAQNP G
Sbjct: 2354 KPKLQWFHNGHEIKPDASH-IAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG 2407



 Score =  185 bits (451), Expect = 1e-44
 Identities = 222/960 (23%), Positives = 383/960 (39%), Gaps = 103/960 (10%)

Query: 599  IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            I+EA + D G  E+ V             D+L    P  S     + +  G  I  E  +
Sbjct: 1895 ILEAEIKDSGRYELKVKNKYGELVTSGWIDVLA--KPEISGLNDTKCLP-GDTICFEALV 1951

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             A P+P ++W    E +   EN  V  + D   Y  V +  +V   ++G YT+ A N EG
Sbjct: 1952 QANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQ--SVSPCEDGKYTITATNSEG 2009

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             A++   L +    ++P  +++P +S  +     V     V G P PTI W K++KP+  
Sbjct: 2010 RAAVDFNLAVLV--EKPTFIVQP-ESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINY 2066

Query: 778  LPTKSDG--------DT-------HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
                  G        DT        S+  +K  +  D G YT  A N  G+ +    + +
Sbjct: 2067 EAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAM 2126

Query: 823  EEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
                      P F+ +    + V +   + L   V  +P+P++ W ++ + + PSE+I  
Sbjct: 2127 LSLA------PSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKI 2180

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--FVKHLQKSYE 939
            + + + +  +  N     DSG YK + SN  G+      V +  E++   F+K +  S  
Sbjct: 2181 STNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPIT-SQT 2239

Query: 940  TEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX-XDVGV 996
               G+ + LE Q +       KWY +   +        I                 D GV
Sbjct: 2240 VVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGV 2299

Query: 997  IKCIVKDQE------TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVW 1049
             KC++ ++       +   +V KE+ P F+ +LQD    E     +++++  +    + W
Sbjct: 2300 YKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQW 2359

Query: 1050 ERDGEIIKPKKNKYDF-EKRGHIRKLYIRNTSVHDEGEYSCILRD-ESCTA--------- 1098
              +G  IKP  +     E   +   L I  T+  D G Y  I ++ E  TA         
Sbjct: 2360 FHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAP 2419

Query: 1099 --EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155
              + T  E  P+ ++ L++   ++G +              V W KDG  +  +  + +T
Sbjct: 2420 KADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMT 2479

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTA-ILTVEEPSINFTLRLPEFILV 1208
             DGK   L I   +  D+G Y+C + N      S C A +  V +P + FT ++ +   V
Sbjct: 2480 CDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPPV-FTQKISDQQQV 2538

Query: 1209 PANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
              N +A + V +      D+ WY +   I  +EK+++ +D     LI+  C + DQ  Y 
Sbjct: 2539 FGN-NAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYK 2597

Query: 1268 CVL--LDAKSTTKLKVEVV--------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
            C+    + K  T+ ++++V          PP  +    +  I  G           +P+P
Sbjct: 2598 CIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEP 2657

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCG----HAD-- 1370
              EW  N + +         I+      LTIK V   D G Y  R+ N  G    HA+  
Sbjct: 2658 EVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELF 2717

Query: 1371 ----------VEMNVTILDK------PSPPGK-PNILEIDSSSINICWDEPENTGNSTII 1413
                      +E   T   K      P P  + P I  +    + + W+          I
Sbjct: 2718 YDSLDSQQKPLEDQYTDFKKYKKSGAPPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPI 2777

Query: 1414 YYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             Y +E  ++   +W +++  +      I+NL+    YRFR    N+  +SD S  T+ Y+
Sbjct: 2778 TYQIEMMDLPEGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYR 2837



 Score =  172 bits (419), Expect = 8e-41
 Identities = 236/1079 (21%), Positives = 410/1079 (37%), Gaps = 93/1079 (8%)

Query: 516  LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT--LVIREV 573
            L+     +G +   E +V   P  +I WF+    I      ++  D   +    L +   
Sbjct: 1611 LKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLA 1670

Query: 574  FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG-I 632
              EDAGT+   A N  G  +ST ++ V          +++             +  EG +
Sbjct: 1671 RTEDAGTYEMKATNFIGETTSTCKVAVLT-----SEALSLEQTVTKTLIATTEEPEEGAV 1725

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P         Q+  E   +  E     IP+P+  W   G+ I PD++ ++ ++ D +   
Sbjct: 1726 PEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYK-- 1783

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIE--PLKSMIVRQG 749
              L++ ++     G Y VV  N+ GE S    L +    E   P + +   LK + V +G
Sbjct: 1784 --LEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841

Query: 750  ESVILSAQVVGNPRPTITWCKNNKP------VKALPTKSDGD------THSITILKPKKV 797
            + V        +P P I   K+ +P      VK    K D +      T ++ IL+  ++
Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILE-AEI 1900

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            KD G Y LK +N  G   TS  I V    E        I+   +       TI   A V 
Sbjct: 1901 KDSGRYELKVKNKYGELVTSGWIDVLAKPE--------ISGLNDTKCLPGDTICFEALVQ 1952

Query: 858  RNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
             NP P ++W R NE +   E   +  + D +   LV  +V S  + G Y   A+NS G++
Sbjct: 1953 ANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSV-SPCEDGKYTITATNSEGRA 2011

Query: 916  SHGARVTIDVEKVTFV--KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS----- 968
            +    + + VEK TF+     Q  ++     T +L        + +W+ + K I+     
Sbjct: 2012 AVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVL-VHGVPLPTIEWFKDDKPINYEAIN 2070

Query: 969  --GMDH---REIIQEGR---XXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI 1016
              G D    +E  ++G                DVG   C+  ++    +    L +    
Sbjct: 2071 KPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLA 2130

Query: 1017 PEFIRKLQD-FEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
            P F++KL +  +V + +  +LE  ++ S    V W +DG+ +KP ++         + KL
Sbjct: 2131 PSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKL 2190

Query: 1075 YIRNTSVHDEGEYSCILRDES------CTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
             I +   +D G Y  I+ +        C   V   E+ P+ +  + +Q V  G     E 
Sbjct: 2191 EINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA 2250

Query: 1129 ELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCT 1186
            ++T   A  V+W+KDG  ++ S  I        Q   I D     DAG Y C + N K  
Sbjct: 2251 QVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIAN-KGG 2309

Query: 1187 AILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDETL-----DVTWYKKKSVIE-D 1238
             I  V +  I      P F+  L  A++     V++  + +      + W+     I+ D
Sbjct: 2310 EIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPD 2369

Query: 1239 TEKFTLISDV-KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP---------- 1287
                 ++ +     +LII K    D   Y  +  + + +T  K ++   P          
Sbjct: 2370 ASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA 2429

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P+ V   R+     G ++ L   + + P P   W  +   +   +    + D K   LTI
Sbjct: 2430 PQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTI 2489

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
            K  E  D+G Y   L N  G      N  +     PP     +             P   
Sbjct: 2490 KPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTV 2549

Query: 1408 GNSTI--IYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
                   + +  + + I  +E  S+KN        + N +      ++  A N       
Sbjct: 2550 SGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDIT 2609

Query: 1465 SETTEYYKVIKE-TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                +    IK+ ++ + P   K + +         + T    G P+P+V W+++ +KL
Sbjct: 2610 QGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKL 2668



 Score =  139 bits (336), Expect = 9e-31
 Identities = 106/411 (25%), Positives = 181/411 (44%), Gaps = 35/411 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATL 568
            P+FV +L+   + +G  V+ + +V G P+P++ WF     IKP +    +  + DN ++L
Sbjct: 2326 PVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSL 2385

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            +I +  P D+G +  +A+N  G  +S  +L V AP +D  +                   
Sbjct: 2386 IIEKTAPGDSGLYEVIAQNPEGSTASKAKLYV-APKADETATEEA--------------- 2429

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                 P F    +    DEG +++L    ++ P P++ W   G  + P+E + +  +   
Sbjct: 2430 -----PQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDG-K 2483

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            H+    L I   +    G YT +  N  GE S      ++   K PP   + +       
Sbjct: 2484 HI---GLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYK-PPVFTQKISDQQQVF 2539

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G +  +   V G P P + W   +KP+   +    K+DGD H + +   +K  D+GVY  
Sbjct: 2540 GNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEK-GDQGVYKC 2598

Query: 806  KAENSEG--IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
             A N EG  I +    I  E      +EPP+F+ +  +  + E    K  A  T  P P 
Sbjct: 2599 IASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPE 2658

Query: 864  ITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAG 913
            + W++N++ + PS+    + +    + L I NV +E D G Y C   N  G
Sbjct: 2659 VEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNV-TEYDVGRYSCRIFNPYG 2708



 Score =  135 bits (327), Expect = 1e-29
 Identities = 202/941 (21%), Positives = 363/941 (38%), Gaps = 101/941 (10%)

Query: 488  LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
            L + + K  +      EE ++  I    +  +H+ +   +++E    G P+P+  W+   
Sbjct: 1705 LEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDG 1764

Query: 548  AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
              I P +   +  D D+   L ++ +   DAG +  V +N  G  S             H
Sbjct: 1765 KPITPDKHTAITVDGDHY-KLEVQSLDLVDAGEYKVVVQNKVGEKS-------------H 1810

Query: 608  GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP--KAQYVDEGSDILLECRLVAIPEPDI 665
              E+++            + I E   P  ++ P  K   V++G  +       A P P+I
Sbjct: 1811 QGELSL------------SGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEI 1858

Query: 666  AWLFKGEEIVPDENISVAI-----ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
              L  G+ +V   N+ + +     E+ +  Y   L I   +    G Y +   N+ GE  
Sbjct: 1859 VLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGE-- 1916

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----- 775
              +V          P+ I  L       G+++   A V  NP+P ++W + N+ +     
Sbjct: 1917 --LVTSGWIDVLAKPE-ISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHEN 1973

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
              +    D D + +        +D G YT+ A NSEG A     + V        E P F
Sbjct: 1974 CEVIADVDADKYRLVFQSVSPCED-GKYTITATNSEGRAAVDFNLAV------LVEKPTF 2026

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-----FDGENIEL 890
            I + +  ++ +   +     V   P+P+I W+++++ I+  E I +      +  E+ + 
Sbjct: 2027 IVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPIN-YEAINKPGKDKLYAKEDTKK 2085

Query: 891  VITNVDS--------EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
                ++S        E D G Y CVA+N  G +    ++ +     +FVK L  + +  +
Sbjct: 2086 GTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAPSFVKKLDNALDVLQ 2145

Query: 943  GKTVILEC--QTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKC 999
            G+ ++LEC    S   + +W  +  E+   +  +I                  D G  K 
Sbjct: 2146 GEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKL 2205

Query: 1000 IVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERD 1052
            I+ +   E   +  V    +E  P+F++ +    V   +   LE ++    A +V W +D
Sbjct: 2206 IISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVTGFPAPEVKWYKD 2265

Query: 1053 GEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPE-- 1108
            G +++P     +     G I  L I      D G Y C++ ++    E V+ VE+ P+  
Sbjct: 2266 GMLLRPSPEINFINSPNGQI-GLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKES 2324

Query: 1109 ---IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQ-FSNHIQLTID-GKKQK 1162
                +  LQ+    +G     +I++       ++WF +G EI+  ++HI +  +      
Sbjct: 2325 KPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSS 2384

Query: 1163 LKIYDCDLDDAGEYSCEVGNSK-CTA----ILTVEEPSINFTLRLPEFIL----VPANTD 1213
            L I      D+G Y     N +  TA    +    +     T   P+F+     V A+  
Sbjct: 2385 LIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEG 2444

Query: 1214 AYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              L +  P   +   +V W K    +   E+  +  D K   L I+     D   YTC+L
Sbjct: 2445 QELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLL 2504

Query: 1271 L----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
                 +  S     V  V  PP       + +   G++  + V     P P+ EW    K
Sbjct: 2505 ANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDK 2564

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             I K +      D     L +   E  D G+YK    N  G
Sbjct: 2565 PIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREG 2605



 Score =  132 bits (318), Expect = 1e-28
 Identities = 114/456 (25%), Positives = 185/456 (40%), Gaps = 47/456 (10%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            D   Y   +     EK+    V  KP    + M P F++ +  +    G  ++ E QV G
Sbjct: 2199 DSGAYKLIISNPHGEKVALCAVAVKP----EEMQPKFLKPITSQTVVVGEPLKLEAQVTG 2254

Query: 536  YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
            +P P++ W++   +++PS +       +    L+I    P DAG + C+  N  G     
Sbjct: 2255 FPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGG----E 2310

Query: 596  TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
             E + +  +    S+                 +   I    + KPK Q+   G +I  + 
Sbjct: 2311 IEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDA 2370

Query: 656  RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
              +AI E             PD + S+ IE                    G Y V+A N 
Sbjct: 2371 SHIAIVEN------------PDNSSSLIIE-------------KTAPGDSGLYEVIAQNP 2405

Query: 716  EG----EASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            EG    +A L +  K  +T  +E PQ +  L+ +   +G+ ++LSA  + NP P + W K
Sbjct: 2406 EGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSK 2465

Query: 771  NN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            +     P + L    DG    +TI KP +  D G YT    N  G  E S+         
Sbjct: 2466 DGVTLTPNERLLMTCDGKHIGLTI-KPAEAADSGNYTCLLANPLG--EDSSACNAN--VR 2520

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            +  +PP+F  +  +         K+   V+  P P + WY  ++ I  SE  +   DG++
Sbjct: 2521 KVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDH 2580

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              L++ N +   D G YKC+ASN  GK     R+ I
Sbjct: 2581 HMLIVNNCEKG-DQGVYKCIASNREGKDITQGRLDI 2615



 Score =  129 bits (311), Expect = 9e-28
 Identities = 267/1222 (21%), Positives = 460/1222 (37%), Gaps = 138/1222 (11%)

Query: 634  PTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMY 691
            P   K  +++Y+  E  ++ +  R+ A PE  + W     EI + D   +V+  SD + Y
Sbjct: 1415 PVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVS--SDGNAY 1472

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               LKIT   +   G YTV A N  G A+    L IK      P+    LK++ V +G+S
Sbjct: 1473 --TLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCA----PEFTHKLKNITVAEGDS 1526

Query: 752  -VILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLK 806
             V L   V   PRP   W  +   +           +G+   + I+       +G YT K
Sbjct: 1527 NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKL-IMNQVATNMQGNYTCK 1585

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
              N  G  E + V+TV      N +P +     + + V+E  +  L   V   P   I W
Sbjct: 1586 IMNDYGKLEDNCVVTV------NCKPKVK-RGLKNVEVQEGKSFTLEVEVYSEPEAKIKW 1638

Query: 867  YRNNEIISPSETITQNFDGENIE--LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923
            +++   I     I  + D + IE   +  N+    D+G Y+  A+N  G+++   +V + 
Sbjct: 1639 FKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVL 1698

Query: 924  -----DVEKVTFVKHLQKSYETEEG----------------KTVILECQTSHTVSTK--- 959
                  +E+      +  + E EEG                ++V L+ +   T   K   
Sbjct: 1699 TSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEA 1758

Query: 960  -WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--------ETSTML 1010
             WYH+ K I+   H  I  +G             D G  K +V+++        E S   
Sbjct: 1759 IWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSG 1818

Query: 1011 VVKETIPEFIRK--LQDFEVKEKDVAILEVEINSETA-DVVWERDGEII------KPKKN 1061
            + +   P   +   L+D +V + D     V   ++ A ++V  +DG+ +      K K +
Sbjct: 1819 IAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVD 1878

Query: 1062 KYDFEKR--GHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQ 1116
            K D E     +   L I    + D G Y   +++   E  T+    V   PEI + L + 
Sbjct: 1879 KKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEI-SGLNDT 1937

Query: 1117 KVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNH----IQLTIDGKKQKLKIYDCDLD 1171
            K   G+   FE +        V W + G+E    NH    +   +D  K +L        
Sbjct: 1938 KCLPGDTICFEALVQANPKPKVSWTR-GNE-NLCNHENCEVIADVDADKYRLVFQSVSPC 1995

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL------ 1225
            + G+Y+    NS+  A +     ++   +  P FI+ P +   +    +  + L      
Sbjct: 1996 EDGKYTITATNSEGRAAVDF---NLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPL 2052

Query: 1226 -DVTWYKKKSVIE-------DTEKFTLISDVKKRT------LIIRKCTEDDQCEYTCVLL 1271
              + W+K    I          +K     D KK T      L I+   E+D   YTCV  
Sbjct: 2053 PTIEWFKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVAT 2112

Query: 1272 DAKSTTK--LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
            +    TK   K+ ++   P  V   +    + +G  + L       P P  +W+ +   +
Sbjct: 2113 NEIGVTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEV 2172

Query: 1329 KKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            K  +  K S +      L I   +  D+G YKL + N  G       V +  KP      
Sbjct: 2173 KPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAV--KPEEMQPK 2230

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVE---YQEIDTTEWISVKNITKTQTSIQNLK 1444
             +  I S ++ +   EP         +   E   Y++          N   +      L 
Sbjct: 2231 FLKPITSQTVVV--GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLI 2288

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
             +++    A     +  +   E     KV    K   P     L++ ++     +++   
Sbjct: 2289 IDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIK 2348

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATY------ENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
              G P+PK+ W+ +G ++K   +        +N                Y+ IA N  G 
Sbjct: 2349 VVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGS 2408

Query: 1559 VETSCVVGIQQKPVITISNED---IKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGN 1611
              +   + +  K   T + E    +     V    G E +++A     P PEVIW K+G 
Sbjct: 2409 TASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGV 2468

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
             L  ++   +T   K   + IK  + + S  YT   +N  G  S      V  K  KP  
Sbjct: 2469 TLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANV-RKVYKP-- 2525

Query: 1672 PVIMREISRESVTI--EWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
            PV  ++IS +        K P+   G+   +L  Y  +K  P + ++  + + D D    
Sbjct: 2526 PVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKY-SIKN-DGDHHML 2583

Query: 1727 CIQKLNENCEYMFRVIAQNPVG 1748
             +    +  + +++ IA N  G
Sbjct: 2584 IVNNCEKGDQGVYKCIASNREG 2605



 Score =  128 bits (309), Expect = 2e-27
 Identities = 222/1026 (21%), Positives = 407/1026 (39%), Gaps = 114/1026 (11%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHS 788
            + P V++ LKS+ V  GE+     Q    P   +TW K+NKP++       T++    +S
Sbjct: 926  DKPVVVKMLKSVQVEPGETAHFEIQFKDQPG-LVTWLKDNKPLEDRLADRITQTAAPMNS 984

Query: 789  ITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAEPPLFINRFQEI 842
              + +K     D G YT++A+++      SA + V      + T+ N EP   ++  ++ 
Sbjct: 985  YRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVS-LKDA 1043

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI---ELVITNVDSE 898
             + E    + + ++  +P P + +Y++  EI+  ++ I    D + +   ELVI +V  +
Sbjct: 1044 EMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQ-K 1102

Query: 899  IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
             D+G Y C A+N  G+++  A  T   +K  F     +     E K V            
Sbjct: 1103 TDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGE-KPVF----------- 1150

Query: 959  KWYHNKKEISGMDHREII--QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012
            +W  N +E    +  +++  ++              D G+  C+ +        S  L V
Sbjct: 1151 QWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSV 1210

Query: 1013 KETIPEFIRKLQD----FEVKEKDV-----AILEVEINSETADVV-WERDGEIIK-PKKN 1061
            +  I    R+ +      E +E +      AILE++        V W+ DGE+I+   ++
Sbjct: 1211 QGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRH 1270

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKV 1118
            K+ +E    +  L I+N    D G Y+    +E    E +   VV+ PP+ I ++ +   
Sbjct: 1271 KFMYEDEESM-SLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPK-IKKITDITC 1328

Query: 1119 NKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTID--GK---KQKLKIYDCDLDD 1172
            + G     EIE+       V+   +G ++   ++++++    GK   K  +++ +  L  
Sbjct: 1329 SAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQ 1388

Query: 1173 AGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227
            AG YS +  N           TV+   +       E+I      +  +TV I       +
Sbjct: 1389 AGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEYI-HGEKENVQMTVRIDAYPEAKL 1447

Query: 1228 TWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVE 1285
            TWY  ++ I+ T+ K+T+ SD    TL I   T  D  +YT    +   S T     +++
Sbjct: 1448 TWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIK 1507

Query: 1286 FPPKIVDYEREYRIKRG-SDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSA 1343
              P+     +   +  G S+V L+V   A+P+P+ +W ++  +I +K    +   +    
Sbjct: 1508 CAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDF 1567

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINI--- 1399
             L + +V     G Y  ++ N+ G  +    VT+  KP    G  N+   +  S  +   
Sbjct: 1568 KLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVE 1627

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
             + EPE         + + Y++         + I     ++   +T  +  +   A N  
Sbjct: 1628 VYSEPEAKIKWFKDGHEI-YEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATN-- 1684

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE--------------------DI 1499
             I + + T +   +  E      TV K L   T EP E                     +
Sbjct: 1685 FIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPL 1744

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
            +   I  G+P+P+  WY DGK +     TA     +                YK +  N 
Sbjct: 1745 KYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNK 1804

Query: 1556 HGEVETS---CVVGIQQ--KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
             GE        + GI +  KP++T     +K  K   GD+     V    P PE++  K+
Sbjct: 1805 VGEKSHQGELSLSGIAEYRKPILT-QGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKD 1863

Query: 1610 GNKLENDKEYNITTKEK---------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            G  +       +   +K         T  + I E +   S +Y ++  N  G       +
Sbjct: 1864 GQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWI 1923

Query: 1661 KVYDKP 1666
             V  KP
Sbjct: 1924 DVLAKP 1929



 Score =  118 bits (284), Expect = 2e-24
 Identities = 263/1254 (20%), Positives = 483/1254 (38%), Gaps = 160/1254 (12%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP--SQDFQMYYDDDNVAT 567
            P+ V+ L+      G T  FE Q +  P   +TW +    ++   +          N   
Sbjct: 928  PVVVKMLKSVQVEPGETAHFEIQFKDQPG-LVTWLKDNKPLEDRLADRITQTAAPMNSYR 986

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXA 626
            L I+     DAGT+T  A++A+   + + +L V +AP  D     T              
Sbjct: 987  LDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT-------------- 1032

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
                   P F    K   + E +      +++  P+P + + +K E+ + + N  + I  
Sbjct: 1033 ------EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKF-YKDEKEILETNDRIQIIR 1085

Query: 687  DM-HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
            D  ++    L I +V+K   GTY+  A N+ GEA+   +    T E + P     L   I
Sbjct: 1086 DKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAI--ATTVEDKNP--FGALSGQI 1141

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSIT-ILKPKKVKDEG 801
            +  GE            +P   W +N +   P +        D  S+  + +  K +D G
Sbjct: 1142 LPAGE------------KPVFQWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAG 1189

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEE-NAEP--PLFINRFQEITVKEKGTIKLVARVTR 858
            +YT  A+ S G    SA ++V+   +  N EP  P  +   +E      G+  L  +   
Sbjct: 1190 IYTCVAQTSTGNISCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKG 1249

Query: 859  NPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
             P P++ W  + E+I   +     + D E++ LVI NVD+ +D+G Y   A N  G+   
Sbjct: 1250 FPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDT-VDAGVYTIEAINELGQDE- 1307

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREI 975
             + + + V+    +K +        G+T+ +E +       + +  +N K+++   + +I
Sbjct: 1308 -SSINLVVKAPPKIKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKI 1365

Query: 976  IQEGRXXXXXXXXXXXXDVGV-------IKCIVKDQETST-MLVVKETIPEFIRKLQ-DF 1026
                             ++ +       IK      +TS       ++ P  ++  + ++
Sbjct: 1366 SSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEY 1425

Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
               EK+   + V I++   A + W  D   IK   +KY     G+   L I   +  D G
Sbjct: 1426 IHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAG 1485

Query: 1086 EYSCILRDE--SCTAEV-TVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVR--- 1138
            +Y+    +E  S T+    +++  PE   +L+N  V +G+     +EL  G DA  R   
Sbjct: 1486 KYTVKATNEHGSATSSTQLLIKCAPEFTHKLKNITVAEGDS---NVELVVGVDAYPRPHA 1542

Query: 1139 -WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192
             W+ DG EI +  N  +   +G   KL +     +  G Y+C++    G  +   ++TV 
Sbjct: 1543 KWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVN 1602

Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKK 1250
             +P +   L+  E   V       L VE+  E    + W+K    I +  +  +  D ++
Sbjct: 1603 CKPKVKRGLKNVE---VQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQR 1659

Query: 1251 -----RTLIIRKCTED----------------DQCEYTCVLLDA----KSTTKLKVEVVE 1285
                  TL + + TED                  C+   +  +A    ++ TK  +   E
Sbjct: 1660 IENYYLTLNLAR-TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTE 1718

Query: 1286 FP-----PKIVDYEREYRIKRGSDVTLLVDYQA--FPQPNDEWIVNSKIIKKCKHTKPSI 1338
             P     P+IV  +  ++      V L  +  A   P+P   W  + K I   KHT  ++
Sbjct: 1719 EPEEGAVPEIVHVD-VFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITV 1777

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-----LDKPSPPGKPNILEID 1393
            D     L ++ ++  DAG YK+ ++N  G    +  +++       KP     P + +I 
Sbjct: 1778 DGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIK 1837

Query: 1394 -SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
             +    +C         +  I  + + Q +  T  + +K + K       ++   +    
Sbjct: 1838 VNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLK-VDKKDAENGLVQYTCTLNIL 1896

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP----LKNITTEPNEDIELTCIFGGV 1508
               + +    +     +Y +++    I    + KP    L +    P + I    +    
Sbjct: 1897 EAEIKDSGRYELKVKNKYGELVTSGWID--VLAKPEISGLNDTKCLPGDTICFEALVQAN 1954

Query: 1509 PQPKVTWYRDGKKL------KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            P+PKV+W R  + L      +       ++               Y   A N  G     
Sbjct: 1955 PKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVD 2014

Query: 1563 CVVGI-QQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG--------N 1611
              + +  +KP  ++   ++ I     V  + LV     G+P P + W+K+         N
Sbjct: 2015 FNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLV----HGVPLPTIEWFKDDKPINYEAIN 2070

Query: 1612 KLENDKEY-NITTKEKT----SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            K   DK Y    TK+ T    SV+ IK  + +    YT  A+N  G +     L
Sbjct: 2071 KPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKL 2124



 Score =  118 bits (284), Expect = 2e-24
 Identities = 113/475 (23%), Positives = 202/475 (42%), Gaps = 54/475 (11%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T   +   P  V + R  +   G +   E Q +G+P+P + W     +I+     +  Y+
Sbjct: 1216 TLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYE 1275

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
            D+   +LVI+ V   DAG +T  A N  G   S+  L+V+AP      ++T         
Sbjct: 1276 DEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAP--PKIKKITDITCSAGET 1333

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                 ++ EG P     +P  Q  + G D+  E  +                 +   +I 
Sbjct: 1334 IKMEIEV-EGFP-----QPTVQVTNNGKDVTAESNVK----------------ISSSSIG 1371

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
             ++E        V+++  +K  Q G Y++ A N   + S      +K+     P +++  
Sbjct: 1372 KSLEK------VVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKS----KPVIVKNF 1421

Query: 742  KSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKK 796
            +S  +  + E+V ++ ++   P   +TW  +   +K   +K    SDG+ +++ I    +
Sbjct: 1422 ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATR 1481

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGTIKLVAR 855
            V D G YT+KA N  G A +S  + ++         P F ++ + ITV E    ++LV  
Sbjct: 1482 V-DAGKYTVKATNEHGSATSSTQLLIK-------CAPEFTHKLKNITVAEGDSNVELVVG 1533

Query: 856  VTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            V   P P   WY +  EI           +G + +L++  V + +  G+Y C   N  GK
Sbjct: 1534 VDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNM-QGNYTCKIMNDYGK 1592

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEI 967
                  VT++ +    VK   K+ E +EGK+  LE +  +      KW+ +  EI
Sbjct: 1593 LEDNCVVTVNCKPK--VKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEI 1645



 Score =  107 bits (258), Expect = 3e-21
 Identities = 267/1243 (21%), Positives = 455/1243 (36%), Gaps = 144/1243 (11%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD-MHMYC 692
            P   +  K   V EG    LE  + + PE  I W   G EI  D  I ++ ++  +  Y 
Sbjct: 1605 PKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYY 1664

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE----------------KEPPQ 736
              L +   +    GTY + A N  GE +    + + T E                +EP +
Sbjct: 1665 LTLNLARTE--DAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEE 1722

Query: 737  --VIEPLKSMIVRQG--ESVILSAQVV--GNPRPTITWCKNNKPV---KALPTKSDGDTH 787
              V E +   + +Q   ESV L  +V+  G P+P   W  + KP+   K      DGD +
Sbjct: 1723 GAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHY 1782

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
             + +     V D G Y +  +N  G       +++    E            ++I V + 
Sbjct: 1783 KLEVQSLDLV-DAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE-------LVITNVDSEI- 899
              +      T +P P I   ++ + +  +  +    D ++ E         +  +++EI 
Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIK 1901

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVS 957
            DSG Y+    N  G+        IDV     +  L  + +   G T+  E   Q +    
Sbjct: 1902 DSGRYELKVKNKYGELVTSG--WIDVLAKPEISGLNDT-KCLPGDTICFEALVQANPKPK 1958

Query: 958  TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX--DVGVIKCIVKDQETSTM----LV 1011
              W    + +   ++ E+I +                + G       + E        L 
Sbjct: 1959 VSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLA 2018

Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII------KPKKNK-Y 1063
            V    P FI + +   + +      +V ++      + W +D + I      KP K+K Y
Sbjct: 2019 VLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINKPGKDKLY 2078

Query: 1064 DFE--KRG--HIRK-LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQ 1114
              E  K+G   I   L I++   +D G Y+C+  +E        ++ ++ L P  + +L 
Sbjct: 2079 AKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAPSFVKKLD 2138

Query: 1115 NQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCD 1169
            N   V +G     E     G  L  V+W KDG E++ S  I+++   DG   KL+I  C 
Sbjct: 2139 NALDVLQGEPLVLEC-CVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLV-KLEINSCQ 2196

Query: 1170 LDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILV---PANTDAYLTVEI 1220
             +D+G Y   + N      + C   +  EE    F   +    +V   P   +A +T   
Sbjct: 2197 PNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVT-GF 2255

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDAKSTTK- 1278
            P    +V WYK   ++  + +   I+    +  LII      D   Y C++ +     + 
Sbjct: 2256 PAP--EVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEG 2313

Query: 1279 -LKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335
              KVE+V  E  P  V   ++     G  V + +     P+P  +W  N   IK      
Sbjct: 2314 VSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHI 2373

Query: 1336 PSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393
              +++   S+SL I+K    D+G+Y++  +N  G    +  + +  K          +  
Sbjct: 2374 AIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFV 2433

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT--------SIQNLK 1444
            S+  ++  DE +    S         + I + + +++  N     T        +I+  +
Sbjct: 2434 SALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAE 2493

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
               S  +     N +    ++      KV K      P   + + +       + ++   
Sbjct: 2494 AADSGNYTCLLANPLGEDSSACNANVRKVYKP-----PVFTQKISDQQQVFGNNAKIPVT 2548

Query: 1505 FGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              GVP P + WY   K + K+ K + +N                   YKCIA N  G+  
Sbjct: 2549 VSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDI 2608

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGD----EWLV---TAVIEGIPPPEVIWYKNGNKL 1613
            T   + I  +      +E      K+GD    E +V   TA   G P PEV W+KN  KL
Sbjct: 2609 TQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKL 2668

Query: 1614 ENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSSVEVTL----------- 1660
                 + I   E   ++R  IK +      +Y+    N  G       L           
Sbjct: 2669 FPSDRFLIDI-EPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELFYDSLDSQQKP 2727

Query: 1661 --------KVYDKPSKP----EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
                    K Y K   P    EGP+I R   R  + + W P +         Y IE  + 
Sbjct: 2728 LEDQYTDFKKYKKSGAPPPLSEGPIISRMTDR-GLLLSWNPSVPLTPRYPITYQIEMMDL 2786

Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
                W  +    R      I+ L    +Y FRV  +N  G S+
Sbjct: 2787 PEGDWRTLRTGVRSC-ACDIRNLEPFRDYRFRVRVENKFGVSD 2828



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 3/155 (1%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            G P P V W+KN   L   K   I+  E   S++R +         Y + A N  G +  
Sbjct: 3590 GDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVA 3649

Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
               + V   P  P+ P I      E + + WK P DDG   +  Y+++    + + W  V
Sbjct: 3650 RCRIVVATLPDAPDSPEISANSGTE-ILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTV 3708

Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            AD + D E Y +  L  N  Y FR+ ++N +G+SE
Sbjct: 3709 AD-NIDHEFYLLHDLQPNTNYQFRLASKNRIGWSE 3742



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 2/151 (1%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEM 1373
            P+P  +W  N  ++ + K  K S+D    S L  +   + D G+YK+   N  G      
Sbjct: 3592 PKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARC 3651

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KN 1432
             + +   P  P  P I     + I + W +P + G+ST++ Y ++Y+  +   W +V  N
Sbjct: 3652 RIVVATLPDAPDSPEISANSGTEILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTVADN 3711

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            I      + +L+ N++Y+FR  + N +  S+
Sbjct: 3712 IDHEFYLLHDLQPNTNYQFRLASKNRIGWSE 3742



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 53/228 (23%), Positives = 92/228 (40%), Gaps = 16/228 (7%)

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKC 1550
            + + EL     G P+PK+T+Y D   +++        T   +               Y+ 
Sbjct: 2898 DHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEA 2957

Query: 1551 IAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            +A N+HGE      + I + P  +   +E      K G    + A + GIP PEV W+K+
Sbjct: 2958 VATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGR---IEAKLVGIPLPEVHWFKD 3014

Query: 1610 GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS- 1667
               + +     I++ +    V+ I +        Y+I A N AG+ S  VT+ + +    
Sbjct: 3015 WKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQ 3074

Query: 1668 ---KPEG--PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
               K  G  P +  +  R     +    L  G   +T +A+E+   DN
Sbjct: 3075 YIYKTYGRHPYVRSKQLRYQDKYDIGDELGRGTQGITYHAVERSSGDN 3122



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 26/109 (23%), Positives = 49/109 (44%)

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            +L +  +     +S  P+F++K+      +G   +F     GYP P++ WF+    + PS
Sbjct: 2612 RLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKLFPS 2671

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
              F +  + + +  L I+ V   D G ++C   N  G      EL  ++
Sbjct: 2672 DRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELFYDS 2720



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 9/127 (7%)

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            G Y  VA N  GEA   + L+I     E P+ ++      +   ++  + A++VG P P 
Sbjct: 2953 GWYEAVATNEHGEARQRVRLEIA----EHPRFLKRPDETFIMARKNGRIEAKLVGIPLPE 3008

Query: 766  ITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            + W K+ KP+    +   +  D D + ++I     +KD G+Y++ A N  G   TS  + 
Sbjct: 3009 VHWFKDWKPIVDSSRIKISSYDPDIYVLSI-HDSIIKDGGLYSISARNIAGSISTSVTVH 3067

Query: 822  VEEPTEE 828
            +EE  ++
Sbjct: 3068 IEENEDQ 3074



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 7/111 (6%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDM 688
            EG PP F +KP+   + E     + C  V  P+P + W FK + ++ + + I ++++ D 
Sbjct: 3561 EGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQW-FKNDMVLTESKRIKISVDEDG 3619

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQV 737
                S+L+      F  G Y VVA N+ G+  A   IV+       + P++
Sbjct: 3620 R---SILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEI 3667



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 2/137 (1%)

Query: 471  AQYLMDENNYTQYLQKKLNEKIDKLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQF 529
            + Y  +E+   + L+ +L  ++D+    +    ++ +   P F EK +     +      
Sbjct: 3525 SMYAANESYSIRRLRTELGPRLDEYTEADAMIETQREGYPPFFREKPQTIAITENQPSHI 3584

Query: 530  ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
             C   G P+P + WF+   ++  S+  ++  D+D  + L        D G +  VA+N  
Sbjct: 3585 HCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKV 3644

Query: 590  GFASSTTELIVEAPLSD 606
            G   +   ++V A L D
Sbjct: 3645 GQTVARCRIVV-ATLPD 3660



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 23/98 (23%), Positives = 44/98 (44%)

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
            T+    PP F  + Q I + E     +      +P P + W++N+ +++ S+ I  + D 
Sbjct: 3558 TQREGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDE 3617

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +   ++        D G YK VA N  G++    R+ +
Sbjct: 3618 DGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVV 3655



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 27/115 (23%), Positives = 61/115 (53%), Gaps = 11/115 (9%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            +++ ARN++G ++      +I +    T P  P +  +S ++   + L+W +P  +G S 
Sbjct: 3636 YKVVARNKVGQTVARC---RIVVA---TLPDAPDSPEISANSGTEILLRWKQPRDDGHST 3689

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSV-HE-HCIENIKEKDEIIFRISAENTVGVS 1949
            +  Y +++K     +WT   TV  ++ HE + + +++      FR++++N +G S
Sbjct: 3690 VLCYSLQYKLSNCDAWT---TVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWS 3741



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 2/107 (1%)

Query: 499  EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
            E+P  +  + AP F+ + +   +       +    V GYP+P++T++    +I+    F 
Sbjct: 2872 ERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFD 2931

Query: 558  MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
              Y  +  ATL I ++   D G +  VA N  G A     L I E P
Sbjct: 2932 QSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHP 2978



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 5/105 (4%)

Query: 494  KLPVFEKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAII 550
            +L V + P  +E   +  P F+  L+     + +  +F  ++ G P+P++ +++ +  I+
Sbjct: 1016 QLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEIL 1075

Query: 551  KPSQDFQMYYDDDNVA--TLVIREVFPEDAGTFTCVAKNAAGFAS 593
            + +   Q+  D D +    LVI +V   DAGT++C A N  G A+
Sbjct: 1076 ETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEAN 1120



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787
            E  PP   E  +++ + + +   +    VG+P+P + W KN+  +   K +    D D  
Sbjct: 3561 EGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGR 3620

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
            SI   +P    D GVY + A N  G       I V    +    P +  N   EI ++ K
Sbjct: 3621 SILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK 3680



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 5/120 (4%)

Query: 822  VEEPTEEN-AEPPLFINRFQEIT--VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            +E P  +  A+ P F+ R Q+I+  VK+  T +L+  V   P P +T+Y ++ +I     
Sbjct: 2871 IERPPHDGLAQAPQFLLREQDISYGVKDHNT-ELMWFVYGYPKPKMTYYFDDMLIESGGR 2929

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
              Q++       +  N   + D G Y+ VA+N  G++    R+ I  E   F+K   +++
Sbjct: 2930 FDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEI-AEHPRFLKRPDETF 2988



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F K+P   ++    +  +E +LV IP P++ W    + IV    I ++   D  +Y  
Sbjct: 2978 PRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS-SYDPDIY-- 3034

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
            VL I +      G Y++ A N  G  S  + + I+  E +
Sbjct: 3035 VLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQ 3074



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 16/175 (9%)

Query: 758  VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814
            V G P+P +T+  ++  +++        T +   T+   K + +D G Y   A N  G A
Sbjct: 2907 VYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEA 2966

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEII 873
                 + +       AE P F+ R  E  +  +   ++ A++   P+P + W+++   I+
Sbjct: 2967 RQRVRLEI-------AEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIV 3019

Query: 874  SPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEK 927
              S     ++D +   L I   DS I D G Y   A N AG  S    VT+ +E+
Sbjct: 3020 DSSRIKISSYDPDIYVLSIH--DSIIKDGGLYSISARNIAGSIS--TSVTVHIEE 3070



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 19/74 (25%), Positives = 38/74 (51%)

Query: 528  QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
            + E ++ G P P++ WF+    I  S   ++   D ++  L I +   +D G ++  A+N
Sbjct: 2996 RIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARN 3055

Query: 588  AAGFASSTTELIVE 601
             AG  S++  + +E
Sbjct: 3056 IAGSISTSVTVHIE 3069


>UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome shotgun
            sequence; n=4; Eumetazoa|Rep: Chromosome 1 SCAF15039,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 3493

 Score =  192 bits (469), Expect = 7e-47
 Identities = 251/1203 (20%), Positives = 444/1203 (36%), Gaps = 105/1203 (8%)

Query: 520  HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
            +T  G     EC+    P P I+W++   ++  S + ++  +      L I+     D G
Sbjct: 998  NTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQ---MLEIKTTGVSDTG 1054

Query: 580  TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
             + C A N AG       L V        + ++V                  +PP   + 
Sbjct: 1055 QYVCKATNIAGQVDKNFHLNVYG-----RARLSVFTHESSCICATMPSQFSAVPPRI-EG 1108

Query: 640  PKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEI----------------------V 675
            P  + + E  G+ +   C    IP P +AWL  G  I                       
Sbjct: 1109 PAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPIGGAAFPSFSRLEMEKCVPLAFTC 1168

Query: 676  PDENISVAIES-DMHMYC--SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
            P E  S   ES +MH++     L+I   +    GTYT VA N EG A     L I+    
Sbjct: 1169 PCELFSENSESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIRV--- 1225

Query: 733  EPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTH 787
             PP++   E  + M V   ES+ L  Q  G P PTI W K+ + V    +   +   D  
Sbjct: 1226 -PPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGT 1284

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
            ++T+       D G Y   A N+ G  +    + V  P   N +        +E T    
Sbjct: 1285 TLTVF-GAHATDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDS----ETVEERTAVLD 1339

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
             ++ L    T +P P + W RN   +  S  +     G+ + +  + V    DSG Y C+
Sbjct: 1340 ASVSLECVATGSPPPQLNWLRNGLPLPLSSHVRLLSAGQVLRITRSQVS---DSGAYSCI 1396

Query: 908  ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKK 965
            ASN AG  S    + + V          +      G  V L C    + T +  W     
Sbjct: 1397 ASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGS 1456

Query: 966  EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKL 1023
             +    +   +                + G   C+ K+   + S    +K   P  I   
Sbjct: 1457 ALFPASNLRFL--NLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRING- 1513

Query: 1024 QDFEVKEKDVAILEVEINSETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
             D   +   +   ++E+  E + V      W +DG   +P  +     + G +  L + +
Sbjct: 1514 SDVVTEVSVIVNNDLELQCEASGVPAPSLTWLKDG---RPLADGLRVLQGGEV--LRVAS 1568

Query: 1079 TSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
              + D G YSC+    +   +   +  V +PP I  + + Q V+        +E  K DA
Sbjct: 1569 AQLEDTGRYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLE-CKSDA 1627

Query: 1136 L----VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAIL 1189
            +    + W KDG  +Q S  +++   G    L+I   +LDD  +Y+CE  N   + T   
Sbjct: 1628 VPPPTLTWLKDGRPLQASARVRILSRG--SYLQINQAELDDRAQYTCEASNIAGQTTRHF 1685

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIE-DTEKFTLISD 1247
             V            + +  P N  A L   +       VTW K  +++  +  ++    D
Sbjct: 1686 NVAVHVAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAED 1745

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVT 1306
                +L I      D   Y C+  +     + +V++ V  PP I +   + ++       
Sbjct: 1746 ---GSLHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTA 1802

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            L  +    P+P   W+ N ++I   ++        S SL +      D  +Y+  + N  
Sbjct: 1803 LSCEASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEA 1862

Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426
            G A   +N+T+   P    +P  + +   S  +           T+ +        +   
Sbjct: 1863 GVASRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEER 1922

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
              S+  +      I + + + + R+   A N      A+ +T  ++ ++ T  + P +  
Sbjct: 1923 GYSI--LPSGPLEITSAELSHTGRYTCTAEN------AAGST--HRHVQLTVQEVPVIAS 1972

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXX 1544
                +       + L C   G P+P ++W ++G  + T   ++                 
Sbjct: 1973 QPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMSISTTGGSFTVLPNGSLRISTTSVSD 2032

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y C+A N  G       + +Q  PV  I ++    +        +   ++G PPP V
Sbjct: 2033 SGTYMCVAQNPAGTALGKIKLKVQVPPV--IGSDTRTYRAPTDSSVTLQCHVDGSPPPSV 2090

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W K+G  L       + +   +  +++  ++   + +YT  A+N AGT S+E++L V  
Sbjct: 2091 TWNKDGQPLAESVRRRVLS---SGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQV 2147

Query: 1665 KPS 1667
             PS
Sbjct: 2148 PPS 2150



 Score =  164 bits (399), Expect = 2e-38
 Identities = 222/1051 (21%), Positives = 406/1051 (38%), Gaps = 80/1051 (7%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G+ + L C     P P ++WL +G  + P  N+   +  +M M      + N      G 
Sbjct: 1432 GNMVSLLCVADGTPTPTVSWLKEGSALFPASNLRF-LNLNMSMQIPQAHVNNT-----GR 1485

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPT 765
            Y+ VA N  G+AS    LK+     +PP++   + +  + V     + L  +  G P P+
Sbjct: 1486 YSCVAKNTAGQASRHFNLKV----LDPPRINGSDVVTEVSVIVNNDLELQCEASGVPAPS 1541

Query: 766  ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            +TW K+ +P+   L     G+   +  +   +++D G Y+  A +  G  +   ++ V  
Sbjct: 1542 LTWLKDGRPLADGLRVLQGGE---VLRVASAQLEDTGRYSCLANSPAGDDDKEFLVRVHV 1598

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P     +     +  Q+++V     + L  +    P P++TW ++   +  S  +     
Sbjct: 1599 PPNIAGK-----SETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVRILSR 1653

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
            G  +++    +D   D   Y C ASN AG+++    V + V     ++   ++      K
Sbjct: 1654 GSYLQINQAELD---DRAQYTCEASNIAGQTTRHFNVAVHV--APSIEEGSQAVSAPVNK 1708

Query: 945  TVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            + +LEC  +        W  +   ++G + R    E              D G   C+  
Sbjct: 1709 SAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAE--DGSLHITSAQVSDTGRYLCMAT 1766

Query: 1003 DQE--TSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP 1058
            +Q       + ++  +P  I + + D +V       L  E +      V W ++G +I  
Sbjct: 1767 NQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINT 1826

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQN 1115
             +N+ +  +      L +   +V D   Y C++ +E+  A   +   V +PP I      
Sbjct: 1827 DQNQ-NMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTVHVPPFIADEPTE 1885

Query: 1116 QKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
              V + +        +   +  V+W KDG  +   N  +         L+I   +L   G
Sbjct: 1886 MVVTRLSPVVMGCSASGVPEPTVQWSKDG--VALPNEERGYSILPSGPLEITSAELSHTG 1943

Query: 1175 EYSC----EVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
             Y+C      G++     LTV+E P I       + IL    T        P  T  ++W
Sbjct: 1944 RYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPT--ISW 2001

Query: 1230 YKKKSVIEDT-EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287
             K+   I  T   FT++ +    +L I   +  D   Y CV  +   T   K+++ V+ P
Sbjct: 2002 QKEGMSISTTGGSFTVLPN---GSLRISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVP 2058

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P I    R YR    S VTL       P P+  W  + + + +    +      S SL +
Sbjct: 2059 PVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRV---LSSGSLQL 2115

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSIN-ICWDEPE 1405
              V++ D G Y     N  G   +EM++T+   PS   G+  +  +++S +  +C    E
Sbjct: 2116 AFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVC--VAE 2173

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
                 T+ +        +++E  +V  +   +  I   +   + R+   A NE+     +
Sbjct: 2174 GVPQPTLSWEKDGNLFSESSEEPTV--LPSGELIITRAQAEDAGRYTCVATNELGQDRWT 2231

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
             T              P   + L ++  +  E + L C   G+P P +TW  +   L   
Sbjct: 2232 ATLSVQ--------THPVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILPVH 2283

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-- 1583
                                  Y C+A N  G +++   V I + P+I   + D++    
Sbjct: 2284 YDHANGHSQLVIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPII---DGDLRSNRI 2340

Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSK 1642
              +G   ++   + G PPP + W KNG  +   D+   +          + E     +  
Sbjct: 2341 EPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQLNNGSLAIYGTVSE----DAGS 2396

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            YT  A+N AG     VTL +   P+  E PV
Sbjct: 2397 YTCVATNDAGAVERSVTLTLQRAPTITEEPV 2427



 Score =  158 bits (383), Expect = 2e-36
 Identities = 240/1171 (20%), Positives = 407/1171 (34%), Gaps = 77/1171 (6%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ V F C   G P P + W +    I  +  F  +   +    + +    P +  +   
Sbjct: 1119 GNPVSFACDATGIPPPALAWLKNGRPIGGAA-FPSFSRLEMEKCVPLAFTCPCELFSENS 1177

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS--KKPK 641
             +     F+      I  + +SD G+   V               +  +PP  S  + P+
Sbjct: 1178 ESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIR-VPPRISGSELPR 1236

Query: 642  AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
               V     I L C+    P P I WL  GE +    +  + I  D     + L +    
Sbjct: 1237 EMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPD----GTTLTVFGAH 1292

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQV 758
                GTY  VA N  GE      L +      PP +    E ++        SV L    
Sbjct: 1293 ATDGGTYACVATNAAGEEDRIFNLNVYA----PPVINGDSETVEERTAVLDASVSLECVA 1348

Query: 759  VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             G+P P + W +N  P+             +  +   +V D G Y+  A N  G+     
Sbjct: 1349 TGSPPPQLNWLRNGLPLPLSSHVRLLSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHY 1408

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             + V  P   +          +++TV     + L+      P P+++W +    + P+  
Sbjct: 1409 NLQVHVPPGLDG-----AGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASN 1463

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS-HGARVTIDVEKVTFVKHLQKS 937
            +   F   N+ + I       ++G Y CVA N+AG++S H     +D  ++     +   
Sbjct: 1464 L--RFLNLNMSMQIPQAHVN-NTGRYSCVAKNTAGQASRHFNLKVLDPPRIN-GSDVVTE 1519

Query: 938  YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                    + L+C+ S     S  W  + + ++  D   ++Q G             D G
Sbjct: 1520 VSVIVNNDLELQCEASGVPAPSLTWLKDGRPLA--DGLRVLQGGE--VLRVASAQLEDTG 1575

Query: 996  VIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEINS-ETADVVW 1049
               C+      +     +V+  +P  I    + QD  V       LE + ++     + W
Sbjct: 1576 RYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTW 1635

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-VELP 1106
             +DG  ++    +     RG    L I    + D  +Y+C   +     T    V V + 
Sbjct: 1636 LKDGRPLQASA-RVRILSRGSY--LQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVA 1692

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164
            P I    Q         A  E  +       V W K G+ +  +N   +   DG    L 
Sbjct: 1693 PSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAEDG---SLH 1749

Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE- 1219
            I    + D G Y C    + G  +    L V  P      RL   + V  N    L+ E 
Sbjct: 1750 ITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLD--VKVTVNVQTALSCEA 1807

Query: 1220 --IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
              IP  T  VTW K   VI   +   +   +   +L++   T +D   Y CV+ +     
Sbjct: 1808 SGIPRPT--VTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVA 1865

Query: 1278 KLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
               + + V  PP I D   E  + R S V +       P+P  +W  +   +   +    
Sbjct: 1866 SRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYS 1925

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
             + S    +T  ++ +T  G Y    EN  G     + +T+ + P    +P+ L++   +
Sbjct: 1926 ILPSGPLEITSAELSHT--GRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKN 1983

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
                      +   TI +   E   I TT   S   +      I     + S  +   A 
Sbjct: 1984 PVTLPCRATGSPRPTISWQ-KEGMSISTTGG-SFTVLPNGSLRISTTSVSDSGTYMCVAQ 2041

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N          T   K+  + ++  P +    +      +  + L C   G P P VTW 
Sbjct: 2042 NPAG-------TALGKIKLKVQV-PPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWN 2093

Query: 1517 RDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            +DG+ L ++ +    +                Y C A N  G V     + +Q  P I  
Sbjct: 2094 KDGQPLAESVRRRVLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRG 2153

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
              +++           +  V EG+P P + W K+GN      E    T   +  + I   
Sbjct: 2154 GEKEVAVVE--NSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEE--PTVLPSGELIITRA 2209

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +   + +YT  A+N  G      TL V   P
Sbjct: 2210 QAEDAGRYTCVATNELGQDRWTATLSVQTHP 2240



 Score =  134 bits (323), Expect = 3e-29
 Identities = 216/1059 (20%), Positives = 384/1059 (36%), Gaps = 114/1059 (10%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            ++ +C+  G P P +TW +     +P  D         V  +   ++  ED G ++C+A 
Sbjct: 1528 LELQCEASGVPAPSLTWLKDG---RPLADGLRVLQGGEVLRVASAQL--EDTGRYSCLAN 1582

Query: 587  NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
                           +P  D   E  V                  +PP  + K + Q V 
Sbjct: 1583 ---------------SPAGDDDKEFLVRVH---------------VPPNIAGKSETQDVS 1612

Query: 647  E--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
                  + LEC+  A+P P + WL  G  +     + +          S L+I   +   
Sbjct: 1613 VLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVRILSRG------SYLQINQAELDD 1666

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
               YT  A N  G+ +    + +       P + E  +++     +S +L   V G P P
Sbjct: 1667 RAQYTCEASNIAGQTTRHFNVAVHVA----PSIEEGSQAVSAPVNKSAVLECVVNGVPPP 1722

Query: 765  TITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
             +TW K+   +     +     DG  H    +   +V D G Y   A N  GI      +
Sbjct: 1723 QVTWRKHGAILAGNNPRYRFAEDGSLH----ITSAQVSDTGRYLCMATNQAGIQRRRVDL 1778

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
             V  P      P +   R  ++ V       L    +  P P++TW +N  +I+  +   
Sbjct: 1779 QVYVP------PSISEGRL-DVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQN 1831

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
                  +  LV+     E D+  Y+CV SN AG +S    +T+ V    F+         
Sbjct: 1832 MYRLLTSGSLVVIAPTVE-DTAVYECVVSNEAGVASRFINLTVHVP--PFIADEPTEMVV 1888

Query: 941  EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
                 V++ C  S         +K  ++  +                       G   C 
Sbjct: 1889 TRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPLEITSAELSHTGRYTCT 1948

Query: 1001 VKDQETST----MLVVKETIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEI 1055
             ++   ST     L V+E +P    +    +V  K+   L      S    + W+++G  
Sbjct: 1949 AENAAGSTHRHVQLTVQE-VPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMS 2007

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITR 1112
            I      +     G +R   I  TSV D G Y C+ ++ + TA   +   V++PP I + 
Sbjct: 2008 ISTTGGSFTVLPNGSLR---ISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVPPVIGSD 2064

Query: 1113 LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             +  +    +  T +  +       V W KDG  +  S   ++   G    L++     +
Sbjct: 2065 TRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRVLSSG---SLQLAFVQSE 2121

Query: 1172 DAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPE-FILVPANTDAYLTV---EIPDETLD 1226
            D G Y+C   N   T  L +     +  ++R  E  + V  N+   L      +P  TL 
Sbjct: 2122 DTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQPTL- 2180

Query: 1227 VTWYKKKSVI-EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
             +W K  ++  E +E+ T++   +   LII +   +D   YTCV  +     +    + V
Sbjct: 2181 -SWEKDGNLFSESSEEPTVLPSGE---LIITRAQAEDAGRYTCVATNELGQDRWTATLSV 2236

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            +  P   +   +  +K+G  + L       P P+  W+ N+ I+    H   +  +  + 
Sbjct: 2237 QTHPVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILP--VHYDHA--NGHSQ 2292

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG--KPNILE-IDSSSINICW 1401
            L I++V   D+G Y    EN  G       V+IL+ P   G  + N +E +  +++  C 
Sbjct: 2293 LVIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPIIDGDLRSNRIEPLGGNAVLNC- 2351

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
             E       TI +       I  T    ++ +     +I    +  +  +   A N+   
Sbjct: 2352 -EVRGDPPPTIRW---SKNGIHITIGDRIRQLNNGSLAIYGTVSEDAGSYTCVATNDAGA 2407

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
             + S T         T  ++PT+ +       +    + L C   G P P + W + G+ 
Sbjct: 2408 VERSVTL--------TLQRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRP 2459

Query: 1522 -LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             L   + +  +                Y+C+A N  G V
Sbjct: 2460 LLGNDRFSSLSNGSLRISSVQKEDTARYECVARNLVGSV 2498



 Score =  132 bits (318), Expect = 1e-28
 Identities = 243/1178 (20%), Positives = 419/1178 (35%), Gaps = 139/1178 (11%)

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
            ++ A +SD G  + V               +   P      P++  V   S + L C   
Sbjct: 858  VLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVVVNSFVSLSCEAT 917

Query: 659  AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718
             +P P + WL     +  + +  +            L+I   K    G Y+ VA+N  GE
Sbjct: 918  GLPPPTLTWLNDRGPVQANTHALIMPGG------RTLQIMKAKVSDGGKYSCVAMNAAGE 971

Query: 719  ASLPIVL------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            A   I L       I+    + P V+  L       G++  L  +    P P+I+W KN 
Sbjct: 972  AHRHIYLTVFIPPSIRGSSGDSPVVVNTLA------GKASTLECETSAVPAPSISWYKNG 1025

Query: 773  KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG------------------IA 814
            + V             +  +K   V D G Y  KA N  G                    
Sbjct: 1026 RVVTESANLRILKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFT 1085

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEII 873
              S+ I    P++ +A PP      +E   +  G  +      T  P P++ W +N   I
Sbjct: 1086 HESSCICATMPSQFSAVPPRIEGPAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPI 1145

Query: 874  S----------------------PSETITQNFDGENIELVITNVDSEI--------DSGD 903
                                   P E  ++N   E++E+ I +   ++        DSG 
Sbjct: 1146 GGAAFPSFSRLEMEKCVPLAFTCPCELFSEN--SESLEMHIFSGGGKLQIARSQVSDSGT 1203

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST--KWY 961
            Y CVASN  G++    R+TI V        L +       +++ L CQ S T +   +W 
Sbjct: 1204 YTCVASNVEGRAHKSYRLTIRVPPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWL 1263

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEF 1019
             + + ++     E+                 D G   C+  +   E   +  +    P  
Sbjct: 1264 KDGEAVNHTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAGEEDRIFNLNVYAPPV 1323

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETA-------DVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            I    D E  E+  A+L+  ++ E          + W R+G +  P  +       G + 
Sbjct: 1324 ING--DSETVEERTAVLDASVSLECVATGSPPPQLNWLRNG-LPLPLSSHVRLLSAGQV- 1379

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNK-GNKATFEI 1128
             L I  + V D G YSCI  + +          V +PP +      + V   G      +
Sbjct: 1380 -LRITRSQVSDSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLL 1438

Query: 1129 ELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
             +  G     V W K+GS +  +++++         ++I    +++ G YSC   N+   
Sbjct: 1439 CVADGTPTPTVSWLKEGSALFPASNLRFL--NLNMSMQIPQAHVNNTGRYSCVAKNTAGQ 1496

Query: 1187 A-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIED 1238
            A     +  ++ P IN +  + E + V  N D  L  E   +P  +L  TW K    + D
Sbjct: 1497 ASRHFNLKVLDPPRINGSDVVTE-VSVIVNNDLELQCEASGVPAPSL--TWLKDGRPLAD 1553

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYE--R 1295
              +     +V    L +     +D   Y+C+    A    K  +  V  PP I      +
Sbjct: 1554 GLRVLQGGEV----LRVASAQLEDTGRYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQ 1609

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +  +     VTL     A P P   W+ + + ++     +  I S+ + L I + E  D 
Sbjct: 1610 DVSVLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVR--ILSRGSYLQINQAELDDR 1667

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
              Y     N  G      NV +   PS       +E  S +++     P N   S ++  
Sbjct: 1668 AQYTCEASNIAGQTTRHFNVAVHVAPS-------IEEGSQAVSA----PVN--KSAVLEC 1714

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            VV         W     I            + S    +  V++        T +     +
Sbjct: 1715 VVNGVPPPQVTWRKHGAILAGNNPRYRFAEDGSLHITSAQVSDTGRYLCMATNQAGIQRR 1774

Query: 1476 ETKIQ---SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
               +Q    P++ +   ++    N    L+C   G+P+P VTW ++G+ + T +     R
Sbjct: 1775 RVDLQVYVPPSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQNMYR 1834

Query: 1533 XXXXXXXXXXX----XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD 1588
                               Y+C+  N+ G       + +   P I  ++E  +       
Sbjct: 1835 LLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTVHVPPFI--ADEPTEMVVTRLS 1892

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
              ++     G+P P V W K+G  L N++  Y+I     +  + I   + SH+ +YT  A
Sbjct: 1893 PVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILP---SGPLEITSAELSHTGRYTCTA 1949

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
             N AG++   V L V + P     P  +  I +  VT+
Sbjct: 1950 ENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTL 1987



 Score =  115 bits (277), Expect = 1e-23
 Identities = 200/933 (21%), Positives = 349/933 (37%), Gaps = 92/933 (9%)

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVA 854
            +V D G YT  A N EG A  S  +T+  P     +E P      +E+ V    +I+LV 
Sbjct: 1197 QVSDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSELP------REMGVLLNESIQLVC 1250

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            + +  P P+I W ++ E ++ + +       +   L +    +  D G Y CVA+N+AG+
Sbjct: 1251 QASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHAT-DGGTYACVATNAAGE 1309

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVST-------KWYHNKKE 966
                  + +    V     +    ET E +T +L+   S   V+T        W  N   
Sbjct: 1310 EDRIFNLNVYAPPV-----INGDSETVEERTAVLDASVSLECVATGSPPPQLNWLRNGLP 1364

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE--TSTMLVVKETIPEFIRKLQ 1024
            +    H  ++  G+            D G   CI  ++    S    ++  +P  +    
Sbjct: 1365 LPLSSHVRLLSAGQVLRITRSQVS--DSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAG 1422

Query: 1025 DFE----VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
              E    V    V++L V   + T  V W ++G  + P  N            + I    
Sbjct: 1423 STEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASNLRFLNLN---MSMQIPQAH 1479

Query: 1081 VHDEGEYSCILRDESCTAE----VTVVELP----PEIITRLQNQKVNKGNKATFEIELTK 1132
            V++ G YSC+ ++ +  A     + V++ P     +++T + +  VN   +   E     
Sbjct: 1480 VNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDVVTEV-SVIVNNDLELQCEASGVP 1538

Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAI 1188
              +L  W KDG  +  ++ +++   G  + L++    L+D G YSC      G+     +
Sbjct: 1539 APSLT-WLKDGRPL--ADGLRVLQGG--EVLRVASAQLEDTGRYSCLANSPAGDDDKEFL 1593

Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLI 1245
            + V  P         + + V  N    L  +   +P  TL  TW K    ++ + +  ++
Sbjct: 1594 VRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTL--TWLKDGRPLQASARVRIL 1651

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304
            S  +   L I +   DD+ +YTC   + A  TT+     V   P I +  +         
Sbjct: 1652 S--RGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVAPSIEEGSQAVSAPVNKS 1709

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
              L       P P   W  +  I+    +      ++  SL I   + +D G Y     N
Sbjct: 1710 AVLECVVNGVPPPQVTWRKHGAIL--AGNNPRYRFAEDGSLHITSAQVSDTGRYLCMATN 1767

Query: 1365 NCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
              G     +++ +   PS   G+ ++      ++N+           T +          
Sbjct: 1768 QAGIQRRRVDLQVYVPPSISEGRLDV----KVTVNV----------QTALSCEASGIPRP 1813

Query: 1424 TTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISD---ASETTEYYKVIKETK 1478
            T  W+    +  T  +  +  L T+ S    A  V +  + +   ++E     + I  T 
Sbjct: 1814 TVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTV 1873

Query: 1479 IQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXX 1535
               P + ++P + + T  +  + + C   GVP+P V W +DG  L   +  Y        
Sbjct: 1874 HVPPFIADEPTEMVVTRLSP-VVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPL 1932

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKHKVGDEWLVT 1593
                        Y C A N  G       + +Q+ PVI    S  D+  K+ V      T
Sbjct: 1933 EITSAELSHTGRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTLPCRAT 1992

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
                G P P + W K G  +      + T     S +RI     S S  Y   A N AGT
Sbjct: 1993 ----GSPRPTISWQKEGMSISTTGG-SFTVLPNGS-LRISTTSVSDSGTYMCVAQNPAGT 2046

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            +  ++ LKV   P         R  +  SVT++
Sbjct: 2047 ALGKIKLKVQVPPVIGSDTRTYRAPTDSSVTLQ 2079



 Score =  105 bits (251), Expect = 2e-20
 Identities = 102/469 (21%), Positives = 197/469 (42%), Gaps = 37/469 (7%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
            PP +     +  V  G  V+L  Q    P PT++W K+ +P+   P  +     S+  + 
Sbjct: 2    PPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSVLRVD 61

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKL 852
              +V+D G Y+ +A N  G  E +  + V   P+   +E P        +TV E   I +
Sbjct: 62   SAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEP------TPLTVIEGNPITM 115

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
            V   +  P PS+ W ++   + P++ +     G  +++   +  +  D+  Y C AS+++
Sbjct: 116  VCESSGIPPPSLVWRKDGSELKPTQRLRVLSGGRQLQI---SSAARTDTASYSCTASSAS 172

Query: 913  GKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISG 969
            G +S    + + V   +   + L       +G  V L+C        +  W  + + +SG
Sbjct: 173  GITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSG 232

Query: 970  MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV------KDQETSTMLVVKETIPEFIRKL 1023
                +++ EGR            D G   C+        D      + V   I   +   
Sbjct: 233  QHRAKVLNEGR--LLQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVP 290

Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
            ++  V  K+   L  E +      + W +DG+ ++   + +        R L + + +V 
Sbjct: 291  ENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGG---RSLRLMHAAVG 347

Query: 1083 DEGEYSCILR----DESCTAEVTVVELPPEIITR--LQNQKVNKGNKATFEIELTKGDAL 1136
            D G Y+C++     +E    ++ ++ +PP I     + + KV + +  T   E++ G+ +
Sbjct: 348  DGGRYTCVVSNMAGEERKNFDLDIL-VPPSIEEEGTVVDTKVKEKHNLTLTCEVS-GNPV 405

Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
              ++W KDG  +    H Q+  +G+   L+I+   + D G YSC   NS
Sbjct: 406  PGIKWLKDGQMLVSDRHHQVFSNGR--FLQIFGTRVADTGRYSCLASNS 452



 Score =  104 bits (250), Expect = 2e-20
 Identities = 117/555 (21%), Positives = 207/555 (37%), Gaps = 35/555 (6%)

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPE 1204
            S  +++ I     KL+I    + D+G Y+C   N +  A     LT+  P       LP 
Sbjct: 1177 SESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSELPR 1236

Query: 1205 FILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             + V  N    L  +     T  + W K    +  T    L       TL +      D 
Sbjct: 1237 EMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHATDG 1296

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF----PQPND 1319
              Y CV  +A         +  + P +++ + E   +R + +   V  +      P P  
Sbjct: 1297 GTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLECVATGSPPPQL 1356

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             W+ N   +    H +  + S    L I + + +D+G Y     N  G      N+ +  
Sbjct: 1357 NWLRNGLPLPLSSHVR--LLSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHYNLQV-- 1412

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
               PPG      +D +      D     GN   +  V +     T  W+   +     ++
Sbjct: 1413 -HVPPG------LDGAGSTE--DVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASN 1463

Query: 1440 IQNLKTNSSYRFRAYAVNE------VDISDASETTEYY--KVIKETKIQSPTVEKPLKNI 1491
            ++ L  N S +     VN       V  + A + + ++  KV+   +I    V   +  +
Sbjct: 1464 LRFLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDV---VTEV 1520

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
            +   N D+EL C   GVP P +TW +DG+ L       +                 Y C+
Sbjct: 1521 SVIVNNDLELQCEASGVPAPSLTWLKDGRPLADGLRVLQGGEVLRVASAQLEDTGRYSCL 1580

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            A +  G+ +   +V +   P I   +E       +     +    + +PPP + W K+G 
Sbjct: 1581 ANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGR 1640

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
             L+      I +  + S ++I + +    ++YT EASN AG ++    + V+  PS  EG
Sbjct: 1641 PLQASARVRILS--RGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVAPSIEEG 1698

Query: 1672 PVIMREISRESVTIE 1686
               +     +S  +E
Sbjct: 1699 SQAVSAPVNKSAVLE 1713



 Score =  102 bits (245), Expect = 9e-20
 Identities = 102/473 (21%), Positives = 179/473 (37%), Gaps = 41/473 (8%)

Query: 514  EKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            E L+PK       S++  EC  + +P P + W++   I++      +      V    + 
Sbjct: 604  EGLKPKEVKVKVNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRMVQ---VE 660

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
                 D G +TCVA N AG      ++ V+ P +   +                 D++  
Sbjct: 661  HARVSDTGRYTCVATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILN 720

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
             P                 I L C   A+P P + W   G+ +   + + +         
Sbjct: 721  NP-----------------ISLYCETNAVPPPTLTWYKDGQLLASGDKVLILPGG----- 758

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              VL+I   +    G Y  +AVN  GE S+   +++         V +  + + V   ++
Sbjct: 759  -RVLQIPRAQAEDAGRYICMAVNEAGEDSIHYDVRVLLPPIIRGTVSDFPEEVTVLVNKT 817

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
              L     GNP P ++W ++++PV+            I  +   +V D G Y   A N  
Sbjct: 818  TQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVA 877

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G AE S  + V  P      P +  +  + + V     + L    T  P P++TW  +  
Sbjct: 878  GSAEKSFNLNVHVP------PMVIGSNPESVNVVVNSFVSLSCEATGLPPPTLTWLNDRG 931

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +  +        G  ++++   V    D G Y CVA N+AG++     +T+ +      
Sbjct: 932  PVQANTHALIMPGGRTLQIMKAKVS---DGGKYSCVAMNAAGEAHRHIYLTVFIPPSIRG 988

Query: 932  KHLQKS--YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980
                      T  GK   LEC+TS     S  WY N + ++   +  I++EG+
Sbjct: 989  SSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQ 1041



 Score =  101 bits (243), Expect = 2e-19
 Identities = 88/337 (26%), Positives = 134/337 (39%), Gaps = 20/337 (5%)

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           V +G D+ L+C    IP P + WL  G  +       V  E  +      L+I  VK   
Sbjct: 201 VTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGRL------LQIKTVKVSD 254

Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            G YT VAVN  G+A     + +        QV  P    +V +   V LS +  G P P
Sbjct: 255 TGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENVSVVLKNP-VALSCEASGIPLP 313

Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            I+W K+ +PV+A  +           L    V D G YT    N  G    +  + +  
Sbjct: 314 AISWLKDGQPVRASSSVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILV 373

Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
           P     E  +      +  VKEK  + L   V+ NPVP I W ++ +++          +
Sbjct: 374 PPSIEEEGTVV-----DTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSN 428

Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE----T 940
           G  +++  T V    D+G Y C+ASNSAG+ S    + + V         + S E    T
Sbjct: 429 GRFLQIFGTRV---ADTGRYSCLASNSAGERSRHYNLNVLVSPTIAGSGPEGSVEEVTVT 485

Query: 941 EEGKTVIL-ECQTSHTVSTKWYHNKKEISGMDHREII 976
               T +L + Q+       W  +       DH  ++
Sbjct: 486 ASSPTSLLCDAQSYPPAVVTWLRDGSSFESSDHVRVL 522



 Score =  101 bits (241), Expect = 3e-19
 Identities = 158/741 (21%), Positives = 271/741 (36%), Gaps = 60/741 (8%)

Query: 476  DENNYTQYLQKKLNE--KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            D   YT  +     E  K   L +   P+ EE+    +   K++ KH      +   C+V
Sbjct: 348  DGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGT--VVDTKVKEKHN-----LTLTCEV 400

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G P P I W +   ++   +  Q++    N   L I      D G ++C+A N+AG  S
Sbjct: 401  SGNPVPGIKWLKDGQMLVSDRHHQVF---SNGRFLQIFGTRVADTGRYSCLASNSAGERS 457

Query: 594  S--TTELIVEAPLSDHGSEMTVXXXXXXXXX-XXXADILEGIPPTFSKKPKAQYVDEGSD 650
                  ++V   ++  G E +V                 +  PP         ++ +GS 
Sbjct: 458  RHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSYPPAV-----VTWLRDGSS 512

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISV-AIESDMHMYCSVLKITNVKKFQEGTYT 709
                  +  +P   +    K  E +           +        L+I N K+   G YT
Sbjct: 513  FESSDHVRVLPGVTLGMTVKMSEGIRSLAYGCHGFITPASAGGRTLQILNAKEEDAGRYT 572

Query: 710  VVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             VA N  GE      LK+           P + ++P K + V+   S+ L       P P
Sbjct: 573  CVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKP-KEVKVKVNSSLTLECAAQAFPSP 631

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             + W K+ + ++     S   +  +  ++  +V D G YT  A N  G  E    + V+ 
Sbjct: 632  ALQWYKDGQILQVDDHMSITASGRMVQVEHARVSDTGRYTCVATNIAGEDEKDFDVNVQV 691

Query: 825  P---TEENAEPPLFINRFQEITVKE---KGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            P   T          +   E  V++      I L       P P++TWY++ ++++  + 
Sbjct: 692  PPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAVPPPTLTWYKDGQLLASGDK 751

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQK 936
            +     G  + L I    +E D+G Y C+A N AG+ S  +  RV +       V    +
Sbjct: 752  VL-ILPGGRV-LQIPRAQAE-DAGRYICMAVNEAGEDSIHYDVRVLLPPIIRGTVSDFPE 808

Query: 937  SYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
                   KT  LEC      + +  W+ + + +       I+  GR            D 
Sbjct: 809  EVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGR--ILQVLTAQVSDT 866

Query: 995  GVIKCIVKDQETST--MLVVKETIPEFI--RKLQDFEVKEKDVAILEVEINS-ETADVVW 1049
            G   C+  +   S      +   +P  +     +   V       L  E        + W
Sbjct: 867  GRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVVVNSFVSLSCEATGLPPPTLTW 926

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELP 1106
              D   +  + N +     G  R L I    V D G+YSC+  + +  A       V +P
Sbjct: 927  LNDRGPV--QANTHALIMPGG-RTLQIMKAKVSDGGKYSCVAMNAAGEAHRHIYLTVFIP 983

Query: 1107 PEIITRLQNQKV----NKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            P I     +  V      G  +T E E +   A  + W+K+G  +  S ++++  +G  Q
Sbjct: 984  PSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEG--Q 1041

Query: 1162 KLKIYDCDLDDAGEYSCEVGN 1182
             L+I    + D G+Y C+  N
Sbjct: 1042 MLEIKTTGVSDTGQYVCKATN 1062



 Score =  100 bits (239), Expect = 5e-19
 Identities = 81/347 (23%), Positives = 146/347 (42%), Gaps = 18/347 (5%)

Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
           S++P    V EG+ I + C    IP P + W   G E+ P + + V            L+
Sbjct: 99  SEEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSGGRQ------LQ 152

Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESVILS 755
           I++  +    +Y+  A +  G  S    L++    +   ++ E L   + V +G  V L 
Sbjct: 153 ISSAARTDTASYSCTASSASGITSKEYSLQVYV--RPSIKLSEGLSDDVAVTKGGDVTLQ 210

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
               G PRP +TW K+ +PV         +   +  +K  KV D G YT  A N+ G A+
Sbjct: 211 CAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQAD 270

Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
           +   ++V  P     +    ++  + ++V  K  + L    +  P+P+I+W ++ + +  
Sbjct: 271 SRHDVSVHVPPVITGQ----VDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRA 326

Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
           S ++     G ++ L+   V    D G Y CV SN AG+      + I V      +   
Sbjct: 327 SSSVHVLSGGRSLRLMHAAVG---DGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTV 383

Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980
              + +E   + L C+ S       KW  + + +    H ++   GR
Sbjct: 384 VDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSNGR 430



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 102/393 (25%), Positives = 158/393 (40%), Gaps = 54/393 (13%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            +   C+    P P +TW++   ++  S D  +      V  L I     EDAG + C+A 
Sbjct: 723  ISLYCETNAVPPPTLTWYKDGQLLA-SGDKVLILPGGRV--LQIPRAQAEDAGRYICMAV 779

Query: 587  NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
            N AG  S   ++ V  P                        I+ G   T S  P+   V 
Sbjct: 780  NEAGEDSIHYDVRVLLP-----------------------PIIRG---TVSDFPEEVTVL 813

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
                  LEC     P P ++W    + + PD    +           +L++   +    G
Sbjct: 814  VNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNG------RILQVLTAQVSDTG 867

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPT 765
             Y  VA N  G A     L +      PP VI    +S+ V     V LS +  G P PT
Sbjct: 868  RYVCVAANVAGSAEKSFNLNVHV----PPMVIGSNPESVNVVVNSFVSLSCEATGLPPPT 923

Query: 766  ITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            +TW  +  PV+A           ++ I+K K V D G Y+  A N+ G A     +TV  
Sbjct: 924  LTWLNDRGPVQANTHALIMPGGRTLQIMKAK-VSDGGKYSCVAMNAAGEAHRHIYLTVFI 982

Query: 825  PTE---ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            P      + + P+ +N     T+  K +  L    +  P PSI+WY+N  +++ S  +  
Sbjct: 983  PPSIRGSSGDSPVVVN-----TLAGKAST-LECETSAVPAPSISWYKNGRVVTESANLRI 1036

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
              +G+ +E+  T V    D+G Y C A+N AG+
Sbjct: 1037 LKEGQMLEIKTTGVS---DTGQYVCKATNIAGQ 1066



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 114/546 (20%), Positives = 215/546 (39%), Gaps = 48/546 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP    +     V  G  ++L C+  AIP P ++W   G  +     ++V  +      
Sbjct: 1    VPPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDG----- 55

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             SVL++ + +    G Y+  A N  G+      L +           EP    ++ +G  
Sbjct: 56   -SVLRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSE-EPTPLTVI-EGNP 112

Query: 752  VILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            + +  +  G P P++ W K+    KP + L   S G    + I    +  D   Y+  A 
Sbjct: 113  ITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSGG--RQLQISSAART-DTASYSCTAS 169

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            ++ GI  TS   +++     + +  L      ++ V + G + L       P P++TW +
Sbjct: 170  SASGI--TSKEYSLQVYVRPSIK--LSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLK 225

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            +   +S         +G  +++    V    D+G Y CVA N+AG++     V++ V  V
Sbjct: 226  DGRPVSGQHRAKVLNEGRLLQIKTVKVS---DTGRYTCVAVNAAGQADSRHDVSVHVPPV 282

Query: 929  -TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             T    + ++        V L C+ S     +  W  + + +       ++  GR     
Sbjct: 283  ITGQVDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGR--SLR 340

Query: 986  XXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEI 1040
                   D G   C+V +   E      +   +P  I +   + D +VKEK    L  E+
Sbjct: 341  LMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEV 400

Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----- 1094
            + +    + W +DG+++   ++   F      R L I  T V D G YSC+  +      
Sbjct: 401  SGNPVPGIKWLKDGQMLVSDRHHQVFSNG---RFLQIFGTRVADTGRYSCLASNSAGERS 457

Query: 1095 -----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQF 1148
                 +     T+    PE    ++   V   +  +   +  +   A+V W +DGS  + 
Sbjct: 458  RHYNLNVLVSPTIAGSGPE--GSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRDGSSFES 515

Query: 1149 SNHIQL 1154
            S+H+++
Sbjct: 516  SDHVRV 521



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 101/459 (22%), Positives = 183/459 (39%), Gaps = 29/459 (6%)

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---------REYRIKR 1301
            RTL I    E+D   YTCV  +    T    E+  F P  ++           +E ++K 
Sbjct: 556  RTLQILNAKEEDAGRYTCVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKPKEVKVKV 615

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
             S +TL    QAFP P  +W  + +I++   H   SI +    + ++    +D G Y   
Sbjct: 616  NSSLTLECAAQAFPSPALQWYKDGQILQVDDHM--SITASGRMVQVEHARVSDTGRYTCV 673

Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQ 1420
              N  G  + + +V +   P+           +SS  +  D  +   N+ I +Y      
Sbjct: 674  ATNIAGEDEKDFDVNVQVPPNFTRAGGAAG-STSSPGVEGDVRDVILNNPISLYCETNAV 732

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRF-RAYAVNE-----VDISDASETTEYYKV- 1473
               T  W     +  +   +  L      +  RA A +      + +++A E + +Y V 
Sbjct: 733  PPPTLTWYKDGQLLASGDKVLILPGGRVLQIPRAQAEDAGRYICMAVNEAGEDSIHYDVR 792

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYEN 1531
            +    I   TV    + +T   N+  +L C   G P P+V+W++D + ++         N
Sbjct: 793  VLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSN 852

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C+A N  G  E S  + +   P++  SN +      V     
Sbjct: 853  GRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPE-SVNVVVNSFVS 911

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            ++    G+PPP + W  +   ++ +    I    +T  ++I + K S   KY+  A N A
Sbjct: 912  LSCEATGLPPPTLTWLNDRGPVQANTHALIMPGGRT--LQIMKAKVSDGGKYSCVAMNAA 969

Query: 1652 GTSSVEVTLKVYDKP----SKPEGPVIMREISRESVTIE 1686
            G +   + L V+  P    S  + PV++  ++ ++ T+E
Sbjct: 970  GEAHRHIYLTVFIPPSIRGSSGDSPVVVNTLAGKASTLE 1008



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 92/331 (27%), Positives = 134/331 (40%), Gaps = 29/331 (8%)

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            ELI+    ++     T             A +     P F++      + +G  +LL C 
Sbjct: 2203 ELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQTHPVFTELLGDVALKKGERLLLACG 2262

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +  IP P I W+F    I+P       +  D     S L I  V K   GTYT VA NR 
Sbjct: 2263 VNGIPTPHITWVF-NNSILP-------VHYDHANGHSQLVIERVTKEDSGTYTCVAENRV 2314

Query: 717  GE-ASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
            G   SL  V  +     EPP +   L+S  I   G + +L+ +V G+P PTI W KN   
Sbjct: 2315 GTIKSLGFVSIL-----EPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIH 2369

Query: 775  VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            +         +  S+ I      +D G YT  A N  G  E S  +T++       EP  
Sbjct: 2370 ITIGDRIRQLNNGSLAIYGTVS-EDAGSYTCVATNDAGAVERSVTLTLQRAPTITEEP-- 2426

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
                     V    T+ L  +    P P+I W +    +  ++  +   +G    L I++
Sbjct: 2427 -----VGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNG---SLRISS 2478

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            V  E D+  Y+CVA N  G  S  ARV + V
Sbjct: 2479 VQKE-DTARYECVARNLVG--SVLARVPLTV 2506



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 102/502 (20%), Positives = 188/502 (37%), Gaps = 35/502 (6%)

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EE 1193
            W KDG  +     + +  DG    L++    + D+G YSCE     G ++    L V   
Sbjct: 36   WRKDGRPLFRKPGLTVLSDGSV--LRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVA 93

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
            PSI  +       ++  N    +          + W K  S ++ T++  ++S    R L
Sbjct: 94   PSIRGSEEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSG--GRQL 151

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER---EYRIKRGSDVTLLV 1309
             I      D   Y+C    A   T  +  + V   P I   E    +  + +G DVTL  
Sbjct: 152  QISSAARTDTASYSCTASSASGITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQC 211

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
              +  P+P   W+ + + +   +H +  + ++   L IK V+ +D G Y     N  G A
Sbjct: 212  AAEGIPRPAVTWLKDGRPVSG-QH-RAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQA 269

Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
            D   +V++   P   G+ ++ E    ++++    P        +        +    W+ 
Sbjct: 270  DSRHDVSVHVPPVITGQVDVPE----NVSVVLKNP------VALSCEASGIPLPAISWLK 319

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNE---VDISDASETTEYYKVIKETKIQSPTVEK 1486
                 +  +S+  L    S R    AV +        ++   E  K      +  P++E+
Sbjct: 320  DGQPVRASSSVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEE 379

Query: 1487 PLKNITTEPNE--DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX 1542
                + T+  E  ++ LTC   G P P + W +DG+ L + +    + N           
Sbjct: 380  EGTVVDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRV 439

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI---EGI 1599
                 Y C+A N  GE      + +   P I  S  +   +         T+++   +  
Sbjct: 440  ADTGRYSCLASNSAGERSRHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSY 499

Query: 1600 PPPEVIWYKNGNKLENDKEYNI 1621
            PP  V W ++G+  E+     +
Sbjct: 500  PPAVVTWLRDGSSFESSDHVRV 521



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 100/510 (19%), Positives = 198/510 (38%), Gaps = 40/510 (7%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            ++   +N T+ L   +++   +DA     IP  TL  +W K    +      T++SD   
Sbjct: 5    IQGEELNATVMLGGPVVLHCQSDA-----IPPPTL--SWRKDGRPLFRKPGLTVLSDGS- 56

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE--YRIKRGSDVTL 1307
              L +      D   Y+C   +    T+    + V   P I   E      +  G+ +T+
Sbjct: 57   -VLRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITM 115

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            + +    P P+  W  +   +K  +  +  + S    L I     TD   Y     +  G
Sbjct: 116  VCESSGIPPPSLVWRKDGSELKPTQRLR--VLSGGRQLQISSAARTDTASYSCTASSASG 173

Query: 1368 HADVEMNVTILDKPS---PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                E ++ +  +PS     G  + + +            E      + + + + + +  
Sbjct: 174  ITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTW-LKDGRPVSG 232

Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
                 V N  +    I+ +K + + R+   AVN    +D+         +    + +  V
Sbjct: 233  QHRAKVLNEGRL-LQIKTVKVSDTGRYTCVAVNAAGQADSRHDVS----VHVPPVITGQV 287

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXX 1542
            + P +N++      + L+C   G+P P ++W +DG+ ++ + + +               
Sbjct: 288  DVP-ENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGRSLRLMHAAV 346

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEG 1598
                 Y C+  N  GE   +  + I   P I    T+ +  +K+KH +     +T  + G
Sbjct: 347  GDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNL----TLTCEVSG 402

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             P P + W K+G  L +D+ + + +  +   ++I   + + + +Y+  ASN+AG  S   
Sbjct: 403  NPVPGIKWLKDGQMLVSDRHHQVFSNGR--FLQIFGTRVADTGRYSCLASNSAGERSRHY 460

Query: 1659 TLKVYDKP----SKPEGPVIMREISRESVT 1684
             L V   P    S PEG V    ++  S T
Sbjct: 461  NLNVLVSPTIAGSGPEGSVEEVTVTASSPT 490



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 86/359 (23%), Positives = 132/359 (36%), Gaps = 46/359 (12%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V  +C  EG PRP +TW +    +      ++  +      L I+ V   D G +TC
Sbjct: 204 GGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEG---RLLQIKTVKVSDTGRYTC 260

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           VA NAAG A S  ++ V  P    G                  D+ E +     K P   
Sbjct: 261 VAVNAAGQADSRHDVSVHVPPVITGQ----------------VDVPENVSVVL-KNP--- 300

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
                  + L C    IP P I+WL  G+ +    ++ V            L++ +    
Sbjct: 301 -------VALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGG------RSLRLMHAAVG 347

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGN 761
             G YT V  N  GE      L I      PP + E   +    V++  ++ L+ +V GN
Sbjct: 348 DGGRYTCVVSNMAGEERKNFDLDILV----PPSIEEEGTVVDTKVKEKHNLTLTCEVSGN 403

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
           P P I W K+ + + +              +   +V D G Y+  A NS G       + 
Sbjct: 404 PVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRVADTGRYSCLASNSAGERSRHYNLN 463

Query: 822 V-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
           V   PT   + P       +E+TV       L+      P   +TW R+      S+ +
Sbjct: 464 VLVSPTIAGSGPE---GSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRDGSSFESSDHV 519



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 45/188 (23%), Positives = 82/188 (43%), Gaps = 4/188 (2%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXX 1539
            P ++    N T      + L C    +P P ++W +DG+ L  K       +        
Sbjct: 3    PNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSVLRVDS 62

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y C A N  G+ E +  + +   P I  S E        G+   +     GI
Sbjct: 63   AQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITMVCESSGI 122

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            PPP ++W K+G++L+  +   + +  +   ++I    R+ ++ Y+  AS+ +G +S E +
Sbjct: 123  PPPSLVWRKDGSELKPTQRLRVLSGGRQ--LQISSAARTDTASYSCTASSASGITSKEYS 180

Query: 1660 LKVYDKPS 1667
            L+VY +PS
Sbjct: 181  LQVYVRPS 188



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 120/533 (22%), Positives = 200/533 (37%), Gaps = 60/533 (11%)

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ------KSYETEEG 943
            L I N   E D+G Y CVA+N AG++     + + V        +       K  + +  
Sbjct: 558  LQILNAKEE-DAGRYTCVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKPKEVKVKVN 616

Query: 944  KTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI- 1000
             ++ LEC  Q   + + +WY + + +   DH  I   GR            D G   C+ 
Sbjct: 617  SSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRMVQVEHARVS--DTGRYTCVA 674

Query: 1001 --VKDQETSTMLVVKETIPEFIR--------KLQDFEVKEKDVAILE-VEINSETADV-- 1047
              +  ++     V  +  P F R             E   +DV +   + +  ET  V  
Sbjct: 675  TNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAVPP 734

Query: 1048 ---VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
                W +DG+++    +K      G +  L I      D G Y C+  +E+    +    
Sbjct: 735  PTLTWYKDGQLLA-SGDKVLILPGGRV--LQIPRAQAEDAGRYICMAVNEAGEDSIHYDV 791

Query: 1103 -VELPPEI---ITRLQNQKVNKGNKAT-FEIELTKGDA-LVRWFKDGSEIQFSNHIQLTI 1156
             V LPP I   ++    +     NK T  E       A  V WF+D   ++     ++  
Sbjct: 792  RVLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILS 851

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANT 1212
            +G+   L++    + D G Y C   N   +A     L V  P +      PE + V  N+
Sbjct: 852  NGRI--LQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSN-PESVNVVVNS 908

Query: 1213 DAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
               L+ E   +P  TL  TW   +  ++      ++     RTL I K    D  +Y+CV
Sbjct: 909  FVSLSCEATGLPPPTL--TWLNDRGPVQANTHALIMPG--GRTLQIMKAKVSDGGKYSCV 964

Query: 1270 LLDAKSTTKLKVEVVEF-PPKI----VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
             ++A       + +  F PP I     D         G   TL  +  A P P+  W  N
Sbjct: 965  AMNAAGEAHRHIYLTVFIPPSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKN 1024

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             +++ +  + +  I  +   L IK    +D G Y  +  N  G  D   ++ +
Sbjct: 1025 GRVVTESANLR--ILKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNV 1075



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 76/355 (21%), Positives = 138/355 (38%), Gaps = 25/355 (7%)

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--CTAEVTV-V 1103
            +VW +DG  +KP +           R+L I + +  D   YSC     S   + E ++ V
Sbjct: 127  LVWRKDGSELKPTQR---LRVLSGGRQLQISSAARTDTASYSCTASSASGITSKEYSLQV 183

Query: 1104 ELPPEIITR---LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGK 1159
             + P I        +  V KG   T +          V W KDG  +   +  ++  +G+
Sbjct: 184  YVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGR 243

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDA 1214
               L+I    + D G Y+C   N+   A     +     P I   + +PE + V      
Sbjct: 244  L--LQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENVSVVLKNPV 301

Query: 1215 YLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
             L+ E     L  ++W K    +  +    ++S    R+L +      D   YTCV+ + 
Sbjct: 302  ALSCEASGIPLPAISWLKDGQPVRASSSVHVLSG--GRSLRLMHAAVGDGGRYTCVVSNM 359

Query: 1274 KSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
                +   ++ +  PP I +     + ++K   ++TL  +    P P  +W+ + +++  
Sbjct: 360  AGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVS 419

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
             +H +  + S    L I      D G Y     N+ G      N+ +L  P+  G
Sbjct: 420  DRHHQ--VFSNGRFLQIFGTRVADTGRYSCLASNSAGERSRHYNLNVLVSPTIAG 472



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 7/186 (3%)

Query: 1479 IQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXX 1536
            ++ P ++  L++   EP   +  L C   G P P + W ++G  +       + N     
Sbjct: 2326 LEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQLNNGSLA 2385

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y C+A ND G VE S  + +Q+ P  TI+ E +      G   ++    
Sbjct: 2386 IYGTVSEDAGSYTCVATNDAGAVERSVTLTLQRAP--TITEEPVGTVVDAGSTVVLNCQA 2443

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            EG P P + W + G  L  +  ++  +      +RI  +++  +++Y   A N  G+   
Sbjct: 2444 EGEPTPTIEWSQQGRPLLGNDRFSSLS---NGSLRISSVQKEDTARYECVARNLVGSVLA 2500

Query: 1657 EVTLKV 1662
             V L V
Sbjct: 2501 RVPLTV 2506



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 98/487 (20%), Positives = 181/487 (37%), Gaps = 54/487 (11%)

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIIT--------RLQNQKVN 1119
            R L I N    D G Y+C+  +E+       E+ V  +PP I          + +  KV 
Sbjct: 556  RTLQILNAKEEDAGRYTCVAANEAGETLKHYELKVF-VPPHINRNDIPGEGLKPKEVKVK 614

Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
              +  T E       +  ++W+KDG  +Q  +H+ +T  G+   +++    + D G Y+C
Sbjct: 615  VNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGR--MVQVEHARVSDTGRYTC 672

Query: 1179 E----VGNSKCTAILTVEEPSINFTLR---------------LPEFILVPANTDAYLTVE 1219
                  G  +    + V+ P  NFT                 + + IL    +    T  
Sbjct: 673  VATNIAGEDEKDFDVNVQVPP-NFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNA 731

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +P  TL  TWYK   ++   +K  ++     R L I +   +D   Y C+ ++      +
Sbjct: 732  VPPPTL--TWYKDGQLLASGDKVLILPG--GRVLQIPRAQAEDAGRYICMAVNEAGEDSI 787

Query: 1280 KVEV-VEFPP----KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
              +V V  PP     + D+  E  +       L       P P   W  +S+ ++     
Sbjct: 788  HYDVRVLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVR--PDG 845

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNILEID 1393
            +  I S    L +   + +D G Y     N  G A+   N+ +   P   G  P  + + 
Sbjct: 846  RHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVV 905

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
             +S      E       T+  ++ +   +       +    +T   I   K +   ++  
Sbjct: 906  VNSFVSLSCEATGLPPPTLT-WLNDRGPVQANTHALIMPGGRT-LQIMKAKVSDGGKYSC 963

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
             A+N    +  +    Y  V     I+  + + P+  + T   +   L C    VP P +
Sbjct: 964  VAMN---AAGEAHRHIYLTVFIPPSIRGSSGDSPVV-VNTLAGKASTLECETSAVPAPSI 1019

Query: 1514 TWYRDGK 1520
            +WY++G+
Sbjct: 1020 SWYKNGR 1026



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+     R    P  S+V  +C V+G P P +TW +    +  S   ++     +  +L 
Sbjct: 2059 PVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRVL----SSGSLQ 2114

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            +  V  ED G +TC A N AG  S    L V+ P S  G E  V              + 
Sbjct: 2115 LAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEV--AVVENSRVQLVCVA 2172

Query: 630  EGIP-PTFSKKPKAQYVDEGSD 650
            EG+P PT S +       E S+
Sbjct: 2173 EGVPQPTLSWEKDGNLFSESSE 2194



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 36/99 (36%), Positives = 49/99 (49%), Gaps = 8/99 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568
            P+F E L       G  +   C V G P P ITW    +I+       ++YD  N  + L
Sbjct: 2240 PVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILP------VHYDHANGHSQL 2293

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSD 606
            VI  V  ED+GT+TCVA+N  G   S   + I+E P+ D
Sbjct: 2294 VIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPIID 2332



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 3/98 (3%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            +AP   E  +    P   +   EC V G P PQ+TW +  AI+  +     + +D    +
Sbjct: 1691 VAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAED---GS 1747

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            L I      D G + C+A N AG      +L V  P S
Sbjct: 1748 LHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPS 1785



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PT +++P    VD GS ++L C+    P P I W  +G  ++ ++  S            
Sbjct: 2420 PTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNGS------ 2473

Query: 694  VLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKE 733
             L+I++V+K     Y  VA N  G   A +P+ +++  G  E
Sbjct: 2474 -LRISSVQKEDTARYECVARNLVGSVLARVPLTVRVHGGFSE 2514



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            + S VQ  C  EG P+P ++W +   +   S +            L+I     EDAG +T
Sbjct: 2162 ENSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEEPTVLPSGE---LIITRAQAEDAGRYT 2218

Query: 583  CVAKNAAGFASSTTELIVE 601
            CVA N  G    T  L V+
Sbjct: 2219 CVATNELGQDRWTATLSVQ 2237



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 29/92 (31%), Positives = 38/92 (41%), Gaps = 4/92 (4%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP   E+        GSTV   CQ EG P P I W +Q   +  +  F    +     +L
Sbjct: 2419 APTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSN----GSL 2474

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             I  V  ED   + CVA+N  G   +   L V
Sbjct: 2475 RISSVQKEDTARYECVARNLVGSVLARVPLTV 2506



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%)

Query: 510  PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            PI    LR     P G      C+V G P P I W +    I      +      N  +L
Sbjct: 2329 PIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQL----NNGSL 2384

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             I     EDAG++TCVA N AG    +  L ++
Sbjct: 2385 AIYGTVSEDAGSYTCVATNDAGAVERSVTLTLQ 2417



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
           E+  P    +G+ +   C+  G P P + W +  + +KP+Q  ++         L I   
Sbjct: 100 EEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVL---SGGRQLQISSA 156

Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIV 600
              D  +++C A +A+G  S    L V
Sbjct: 157 ARTDTASYSCTASSASGITSKEYSLQV 183


>UniRef50_Q1JPV5 Cluster: Zgc:136545; n=3; Danio rerio|Rep: Zgc:136545
            - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 822

 Score =  192 bits (468), Expect = 9e-47
 Identities = 152/582 (26%), Positives = 253/582 (43%), Gaps = 40/582 (6%)

Query: 1019 FIRKLQDFEVKEKDVAI-LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            F++KL      EK   I L VE+    A V W ++G+ IKP   KY FE  G IRKL I 
Sbjct: 229  FLKKLDPAYSVEKGKKIQLSVELTDPNAQVKWLKNGQEIKPSA-KYVFESVGGIRKLTIN 287

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
              ++ D+  Y C++ +E    EV + E P  I   L +  V +G+K  FE+E++   A V
Sbjct: 288  KCTLADDAAYECVVGEEKSFTEVFIQEPPVTITKMLDDAHVVEGDKVEFEVEVSDEGANV 347

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            +W KDG E+      +   DG K  L I +   +D G Y       +  A L VEE  + 
Sbjct: 348  KWMKDGVELSRDGKYRFKKDGTKHWLIINEATTEDIGTYYVYTSGGESKAELEVEERELE 407

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
                + + + V A   A    E+ DE +   W+K    +  +++  +    +   L+I  
Sbjct: 408  VLQSIAD-LTVKAAEQAVFKCEVSDEKVTGKWFKDGVEVVASDRIKMSHIGRTHKLVISD 466

Query: 1258 CTEDDQCEYTCV------LLDAK-STTKLKVEVV--EFPPKI-------VDYEREYRIKR 1301
               +D  +YT V       L AK +  ++K++ V  + PPKI       +  +    +  
Sbjct: 467  VKPEDAGDYTFVPDGYALSLSAKLNFLEIKIDYVPRQEPPKIHLDATGSMVNKNTIIVVA 526

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYK 1359
            G+ +   VD    P P   W      I + +  +  ++++ A     I+  E +D G+Y 
Sbjct: 527  GNKLRFDVDITGEPPPTVAWKKGDMEISQAE-GRVRVETRKALSCFVIEGAERSDEGLYH 585

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
            + + N  G    ++ V I+D P PP     L +   S +I W  P++ GN+ II Y V+ 
Sbjct: 586  ITVTNPAGEDKADVFVKIVDVPDPPENVKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQK 645

Query: 1420 QEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             +  T EW +V ++  +   ++ +L   + Y FR ++ N   +S+ +  ++   VI +T 
Sbjct: 646  ADKKTKEWFTVLEHNCRPSCTVSDLVMGNEYFFRIFSENICGMSEEAGLSKNTAVIAKTG 705

Query: 1479 IQ-------------SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----GKK 1521
            +Q             SP    PL + +        ++C   G P+PK+ W ++    G+ 
Sbjct: 706  LQYKPQPYKEKDMNSSPKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGED 765

Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
             K      +                 Y C A ND GE E  C
Sbjct: 766  PKFLMQNNQGVLTLNIRKPSLFDCGKYTCKAINDLGEDEVEC 807



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 51/174 (29%), Positives = 83/174 (47%), Gaps = 8/174 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            I G PPP V W K   ++   +    + T++  S   I+  +RS    Y I  +N AG  
Sbjct: 536  ITGEPPPTVAWKKGDMEISQAEGRVRVETRKALSCFVIEGAERSDEGLYHITVTNPAGED 595

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
              +V +K+ D P  PE  V    +  +S +IEWKPP D+G  ++  Y ++K +     W 
Sbjct: 596  KADVFVKIVDVPDPPEN-VKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQKADKKTKEWF 654

Query: 1715 KVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEAL---ESEPIVIKTAL 1764
             V  ++ +    C +  L    EY FR+ ++N  G SE     ++  ++ KT L
Sbjct: 655  TV--LEHNCRPSCTVSDLVMGNEYFFRIFSENICGMSEEAGLSKNTAVIAKTGL 706



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 90/371 (24%), Positives = 144/371 (38%), Gaps = 32/371 (8%)

Query: 835  FINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
            F+ +       EKG  I+L   +T +P   + W +N + I PS        G   +L I 
Sbjct: 229  FLKKLDPAYSVEKGKKIQLSVELT-DPNAQVKWLKNGQEIKPSAKYVFESVGGIRKLTI- 286

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953
            N  +  D   Y+CV     G+      V I    VT  K L  ++  E G  V  E + S
Sbjct: 287  NKCTLADDAAYECVV----GEEKSFTEVFIQEPPVTITKMLDDAHVVE-GDKVEFEVEVS 341

Query: 954  HT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012
                + KW  +  E+S        ++G             D+G         E+   L V
Sbjct: 342  DEGANVKWMKDGVELSRDGKYRFKKDGTKHWLIINEATTEDIGTYYVYTSGGESKAELEV 401

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG-EIIKPKKNKYDFEKRGHI 1071
            +E   E ++ + D  VK  + A+ + E++ E     W +DG E++   + K     R H 
Sbjct: 402  EERELEVLQSIADLTVKAAEQAVFKCEVSDEKVTGKWFKDGVEVVASDRIKMSHIGRTH- 460

Query: 1072 RKLYIRNTSVHDEGEYSCILRDE--SCTAEVTVVEL---------PPEIITRLQNQKVNK 1120
             KL I +    D G+Y+ +      S +A++  +E+         PP+I        VNK
Sbjct: 461  -KLVISDVKPEDAGDYTFVPDGYALSLSAKLNFLEIKIDYVPRQEPPKIHLDATGSMVNK 519

Query: 1121 -------GNKATFEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLD 1171
                   GNK  F++++T +    V W K   EI Q    +++          I   +  
Sbjct: 520  NTIIVVAGNKLRFDVDITGEPPPTVAWKKGDMEISQAEGRVRVETRKALSCFVIEGAERS 579

Query: 1172 DAGEYSCEVGN 1182
            D G Y   V N
Sbjct: 580  DEGLYHITVTN 590



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           ++ + +P F+  L  +    G +    C V G P+P+I W +   II     F M  ++ 
Sbjct: 716 KDMNSSPKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGEDPKFLM-QNNQ 774

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAG 590
            V TL IR+    D G +TC A N  G
Sbjct: 775 GVLTLNIRKPSLFDCGKYTCKAINDLG 801



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 7/153 (4%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            IE  +  DE ++ I+  N  G     E ++    K   VP PP   ++   VG +     
Sbjct: 573  IEGAERSDEGLYHITVTNPAG-----EDKADVFVKIVDVPDPPEN-VKCLGVGEDSASIE 626

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ +G   ++GY +   D     W  V + +       + DL   + Y  RI++ N 
Sbjct: 627  WKPPKDNGNTDIIGYTVQKADKKTKEWFTVLEHNCRP-SCTVSDLVMGNEYFFRIFSENI 685

Query: 2047 IGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
             G+SE     +   VI   G     +P ++ ++
Sbjct: 686  CGMSEEAGLSKNTAVIAKTGLQYKPQPYKEKDM 718



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 4/97 (4%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITI 791
           P+ I PL    V  G S  +S  V G P+P I W KN   +   P    +++    ++ I
Sbjct: 722 PKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGEDPKFLMQNNQGVLTLNI 781

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            KP  + D G YT KA N  G  E    + V   TE+
Sbjct: 782 RKP-SLFDCGKYTCKAINDLGEDEVECRLEVRVVTEK 817



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 21/79 (26%), Positives = 36/79 (45%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            ++  + G P P++IW KN   +  D ++ +   +    + I++       KYT +A N  
Sbjct: 741  ISCAVRGCPKPKIIWMKNKMIIGEDPKFLMQNNQGVLTLNIRKPSLFDCGKYTCKAINDL 800

Query: 1652 GTSSVEVTLKVYDKPSKPE 1670
            G   VE  L+V     K E
Sbjct: 801  GEDEVECRLEVRVVTEKEE 819



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 21/178 (11%)

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VL 725
           W   G E+V  + I ++     H     L I++VK    G YT V        S  +  L
Sbjct: 438 WFKDGVEVVASDRIKMSHIGRTHK----LVISDVKPEDAGDYTFVPDGYALSLSAKLNFL 493

Query: 726 KIKTG---EKEPPQV-IEPLKSM------IVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
           +IK      +EPP++ ++   SM      IV  G  +     + G P PT+ W K +  +
Sbjct: 494 EIKIDYVPRQEPPKIHLDATGSMVNKNTIIVVAGNKLRFDVDITGEPPPTVAWKKGDMEI 553

Query: 776 KALPTKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETSA---VITVEEPTE 827
                +   +T    S  +++  +  DEG+Y +   N  G  +      ++ V +P E
Sbjct: 554 SQAEGRVRVETRKALSCFVIEGAERSDEGLYHITVTNPAGEDKADVFVKIVDVPDPPE 611



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 3/101 (2%)

Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
            P   D      K +  P  P N         S +++W  P+ NG + I  Y ++    K 
Sbjct: 591  PAGEDKADVFVKIVDVPDPPENVKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQKADKKT 650

Query: 1910 KSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVS 1949
            K W  ++    +    C + ++   +E  FRI +EN  G+S
Sbjct: 651  KEWFTVLE--HNCRPSCTVSDLVMGNEYFFRIFSENICGMS 689



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 8/125 (6%)

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
            + I+    + E ++ +   NP G     E +  V    +DVP           +  +S  
Sbjct: 571  FVIEGAERSDEGLYHITVTNPAG-----EDKADVFVKIVDVPDPPENVKCLG-VGEDSAS 624

Query: 1786 ITWFPSEKNGGSPIIDYKVE-IKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
            I W P + NG + II Y V+   ++ K+W             +  L +   Y FRI++ N
Sbjct: 625  IEWKPPKDNGNTDIIGYTVQKADKKTKEWFTVLEHNCRPSCTVSDLVMGNEYFFRIFSEN 684

Query: 1844 EIGTS 1848
              G S
Sbjct: 685  ICGMS 689


>UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo
            sapiens (Human)
          Length = 7968

 Score =  192 bits (467), Expect = 1e-46
 Identities = 166/673 (24%), Positives = 287/673 (42%), Gaps = 42/673 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++ +P  F++  + +   EG+  +L C L  +    + W  KG E + D +  +  +   
Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWR-KGPENLRDGDRYILRQEGT 3501

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
               C  L+I  +     G Y  V       A+L I          P + IE +K+   R+
Sbjct: 3502 R--CE-LQICGLAMADAGEYLCVCGQERTSATLTI-------RALPARFIEDVKNQEARE 3551

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G + +L  ++  N    + W K ++ ++       + DG    + I +   + D G Y+ 
Sbjct: 3552 GATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQI-RGLAMADTGEYSC 3608

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
                  G   TSA++TV       A P  F    +     E  T   V R   + +  + 
Sbjct: 3609 VC----GQERTSAMLTVR------ALPIKFTEGLRNEEATEGATA--VLRCELSKMAPVE 3656

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W++ +E +   +  +   DG   EL I  + +E D+G+Y C+     GK    A +T+  
Sbjct: 3657 WWKGHETLRDGDRHSLRQDGARCELQIRGLVAE-DAGEYLCMC----GKERTSAMLTVRA 3711

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
                F++ L+   E  EG T  L C+ S     +W    + +   D   + Q+G      
Sbjct: 3712 MPSKFIEGLRNE-EATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D G   C+   + TS  L V+     FI  +++ E +E   A+L+ E+ S+ A
Sbjct: 3771 IRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCEL-SKAA 3829

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
             V W +  E ++   ++Y   + G   +L I   SV D GEYSC+   E  +A +TV   
Sbjct: 3830 PVEWRKGSETLRGG-DRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAP 3888

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
             P     LQ+ +  +G+ AT + EL++  A V W K G ++Q +   +  + G   +L +
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
             D   +D GEY+C  G+   +A LTV    + F LR  +   V     A+L  E+     
Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRF-LRELQHQEVDEGGTAHLCCELSRAGA 4007

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-- 1283
             V W K    +    K+ ++ D     L++R   ++D  +YTC     +S   L V V  
Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPR 4067

Query: 1284 VEFPPKIVDYERE 1296
             +F  ++   E+E
Sbjct: 4068 PKFKTRLQSLEQE 4080



 Score =  189 bits (461), Expect = 6e-46
 Identities = 271/1259 (21%), Positives = 487/1259 (38%), Gaps = 118/1259 (9%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F   L+   T +   V  EC++   P   + W +    ++  +   +       +  + R
Sbjct: 2168 FSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYR 2226

Query: 572  EVFPEDAGTFTCVAKNAAGFAS-----STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
              F  D G + C A +A   AS      T  LI    L++   E+               
Sbjct: 2227 CEFA-DQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR- 2284

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
              ++ +P T  +  + +   E    +LEC+ V+     + W    +E+ P     +  + 
Sbjct: 2285 --VKELPVTLVRPLRDKIAMEKHRGVLECQ-VSRASAQVRWFKGSQELQPGPKYELVSDG 2341

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
               +Y  ++ I++V    E TYT  A + +  A   +       E++   ++  L+ + V
Sbjct: 2342 ---LYRKLI-ISDVHAEDEDTYTCDAGDVKTSAQFFV-------EEQSITIVRGLQDVTV 2390

Query: 747  RQGESVILSAQV-VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802
             +        +  + + RP   W      ++A   +  + +G  H + + +        V
Sbjct: 2391 MEPAPAWFECETSIPSVRPP-KWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPV 2449

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            +      + G + +SA + V +       P +     +  T +E  ++ L       P  
Sbjct: 2450 HF-----TVGKSRSSARLVVSDI------PVVLTRPLEPKTGRELQSVVLSCDFRPAP-K 2497

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            ++ WY+++  +SPSE    + +G+  EL I  +    D+G Y+C     AG +     VT
Sbjct: 2498 AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRL-MPADAGVYRC----QAGSAHSSTEVT 2552

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
            ++  +VT    LQ +  TEEG      C+ SH     +W  N   +      EI  +GR 
Sbjct: 2553 VEAREVTVTGPLQDAEATEEG-WASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G+++       TS  L V+     F++ L D   +E+    L+ E++
Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
               A VVW +DG  + P  +KYDF      R L + + S  D G Y+C +  E   A V 
Sbjct: 2672 DPEAHVVWRKDGVQLGPS-DKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVR 2730

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159
            V +L   I  RL+  +V +G   +FE  L+   A     W   G  +  S+  Q T  G+
Sbjct: 2731 VHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGR 2790

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            K  L + +    DAGE    V      A L V E        L +  + P   D  L  E
Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGE-DVELRCE 2849

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +      V W K +  I  ++K+ ++ +     L+IR  +  D  EYTC +  +KST  L
Sbjct: 2850 LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTASL 2909

Query: 1280 KVEVVE--FPPKIVDYEREYRIKRGSDV-TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             VE     F  ++ + + E   ++G+ V T   ++   P     W      ++     +P
Sbjct: 2910 HVEEKANCFTEELTNLQVE---EKGTAVFTCKTEH---PAATVTWRKGLLELRASGKHQP 2963

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
            S +  +  LTI  +E  D+  Y   +    G A     + +  +     + +I+E D   
Sbjct: 2964 SQEGLTLRLTISALEKADSDTYTCDI----GQAQSRAQLLVQGR-----RVHIIE-DLED 3013

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            +++        G+S      +     +   W   K  T    +  N        +    +
Sbjct: 3014 VDV------QEGSSATFRCRISPANYEPVHWFLDK--TPLHANELNEIDAQPGGYHVLTL 3065

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTV-EKP------LKNITTEPNEDIELTCIFGGVP 1509
             ++ + D+   T Y++   +    +  V EKP      L + T    ED+ L C      
Sbjct: 3066 RQLALKDSG--TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCD 3123

Query: 1510 QPKVTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P V W +DGK L+ +   + ++E +R               YKC A    G   +S +V
Sbjct: 3124 IP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIV 3178

Query: 1566 GIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
             +  +PV     E +K    + G    +  V+  +  P V W    N L    +Y++  +
Sbjct: 3179 RVHARPVRF--QEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQE 3235

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
                 + ++ L+   S +Y    S + G  +   TL V   P++  G +  +E +     
Sbjct: 3236 GAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTALPAQFIGKLRNKEAT----- 3286

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
                    +G     +  + K  P    W K ++  RD + YC+++    CE   R +A
Sbjct: 3287 --------EGATATLRCELSKAAPVE--WRKGSETLRDGDRYCLRQDGAMCELQIRGLA 3335



 Score =  180 bits (437), Expect = 5e-43
 Identities = 169/669 (25%), Positives = 275/669 (41%), Gaps = 39/669 (5%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L I+ ++K    TYT      +  A L +       +     +IE L+ + V++G S   
Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLV-------QGRRVHIIEDLEDVDVQEGSSATF 3024

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENS 810
              ++       + W  +  P+ A          G  H +T L+   +KD G    +A   
Sbjct: 3025 RCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLT-LRQLALKDSGTIYFEA--- 3080

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G    SA + V E      +P +F     + T+ E   + LV   +   +P + W ++ 
Sbjct: 3081 -GDQRASAALRVTE------KPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDG 3132

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            + +  S     + +G   +L+IT    + DSG YKC A  +   S     V +    V F
Sbjct: 3133 KTLRGSARCQLSHEGHRAQLLITGATLQ-DSGRYKCEAGGACSSSI----VRVHARPVRF 3187

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
             + L K  E  EG    L C  S   +  KW +    +   D   + QEG          
Sbjct: 3188 QEAL-KDLEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
               D G   C   DQ TS  L V     +FI KL++ E  E   A L  E+ S+ A V W
Sbjct: 3247 RPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCEL-SKAAPVEW 3305

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             +  E ++   ++Y   + G + +L IR  ++ D  EYSC+  +E  +A +T+  +P   
Sbjct: 3306 RKGSETLRDG-DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHF 3364

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
            I RL++Q+  +G  AT   EL+K  A V W K    ++  +   L  DG   +L+I    
Sbjct: 3365 IGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDGDRHSLRQDGAVCELQICGLA 3423

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            + DAGEYSC  G  + +A LTV+     FT  L     V   T A L  E+  +   V W
Sbjct: 3424 VADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGAT-AMLWCEL-SKVAPVEW 3481

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
             K    + D +++ L  +  +  L I      D  EY CV    +++  L +  +  P +
Sbjct: 3482 RKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL--PAR 3539

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
             ++  +    + G+   L  +  +      EW   S+ ++         D     L I+ 
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAAPV--EWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597

Query: 1350 VENTDAGIY 1358
            +   D G Y
Sbjct: 3598 LAMADTGEY 3606



 Score =  170 bits (414), Expect = 3e-40
 Identities = 196/889 (22%), Positives = 349/889 (39%), Gaps = 58/889 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +  +P  F +  K Q   EG+  +L+C L  A P   + W    E +   +  S+  +  
Sbjct: 3797 VRALPARFIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLRGGDRYSLRQDGT 3853

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                C  L+I  +     G Y+ V       A+L +           P   EPL+S+   
Sbjct: 3854 R---CE-LQIHGLSVADTGEYSCVCGQERTSATLTV-------RAPQPVFREPLQSLQAE 3902

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYT 804
            +G +  L  ++   P  T+ W K    ++A   +     G T  + +L+  + +D G YT
Sbjct: 3903 EGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAEL-VLQDLQREDTGEYT 3960

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
                   G   TSA +TV       A P  F+   Q   V E GT  L   ++R    S+
Sbjct: 3961 CTC----GSQATSATLTV------TAAPVRFLRELQHQEVDEGGTAHLCCELSRAGA-SV 4009

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W + +  + P        DG   EL++  V+ E D+GDY C      G +   A +++ 
Sbjct: 4010 EWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQE-DAGDYTC----DTGHTQSMASLSVR 4064

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKEISGMDHREIIQEGRX 981
            V +  F   LQ S E E G    L CQ S   S    +W     E+      E+  +G  
Sbjct: 4065 VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D G   C+   Q+T+  L V E     +R L D EV   +      E++
Sbjct: 4124 RELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVS 4183

Query: 1042 SETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
               A  V W   G  ++  +      + G I  L ++  +  D G  S  L + + +A++
Sbjct: 4184 RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQL 4243

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID-G 1158
            TV      I+  LQ+ ++++G  A+F+  L++      RW   G  +Q +    +T++ G
Sbjct: 4244 TVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQG 4303

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
                L ++   L+DAG  S  VG   C++   ++  + N  +R  E +      +A    
Sbjct: 4304 TLHLLTLHKVTLEDAGTVSFHVGT--CSSEAQLKVTAKNTVVRGLENVEALEGGEALFEC 4361

Query: 1219 EIPD-ETLDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            ++   E    TW      +  +E   ++   +  +  L+++     D C  T +  D  +
Sbjct: 4362 QLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVT 4421

Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPNDEWIVNSKIIKKCKHT 1334
            +  L V       +I++  +   ++ G+         +A P     W +N   ++     
Sbjct: 4422 SAFLTVRGWRL--EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSD 4479

Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393
               + D    +L ++  +   AG     +   C  A     +T+L  P PP    ++   
Sbjct: 4480 WTVTADGSHHALLLRSAQPHHAG----EVTFACRDAVASARLTVLGLPDPPEDAEVVARS 4535

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFR 1452
            S ++ + W  P + G   +  Y VE +E  T +W +  + +   +  +  L    +YRFR
Sbjct: 4536 SHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFR 4595

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
              AV  V   +     +  ++ +  K   P    P ++      ED+ L
Sbjct: 4596 VAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAP-ESRQVAAGEDVSL 4643



 Score =  161 bits (392), Expect = 1e-37
 Identities = 179/903 (19%), Positives = 342/903 (37%), Gaps = 56/903 (6%)

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            +DEG Y+ +     G       + V EP    A+  L   + Q     E G    ++   
Sbjct: 863  QDEGTYSCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQA----EAGASATLSCEV 914

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
                  +TWY++ + +S S  +     G    LV+     + D+G+Y C     AG    
Sbjct: 915  AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQA-GQADAGEYSC----EAGGQRL 969

Query: 918  GARVTIDVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHRE 974
               + +   KV F K        + E G +  L C+ +       WY + K++S      
Sbjct: 970  SFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVH 1029

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL---QDFEVKEK 1031
            +  +G             D G   C  + Q  S  L + E    F ++     + + +  
Sbjct: 1030 VEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAG 1089

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
              A+L  E+     +V W +DG+ +    +K   E +G  R+L +      D GEYSC  
Sbjct: 1090 ASAMLSCEVAQAQTEVTWYKDGKKLS-SSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148

Query: 1092 RDESCTAEVTVVELPPEIITRLQN----QKVNKGNKATFEIELTKGDALVRWFKDGSEIQ 1147
              +  +  + + E P  +  + Q+     +   G  A    E+ +    V W+KDG ++ 
Sbjct: 1149 GGQRVSFHLHITE-PKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLS 1207

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEF 1205
             S+ +++ + G  ++L +      DAGEYSCE G  + +  L + EP   F     +   
Sbjct: 1208 SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNE 1267

Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
            +   A   A L+ E+     +VTWYK    +  + K  + +    R L++++  + D  E
Sbjct: 1268 VRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGE 1327

Query: 1266 YTCVLLDAKSTTKLKV-EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
            YTC     + +  L V E      K     R+ + + G+  TL  +  A  Q    W  +
Sbjct: 1328 YTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKD 1386

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDKPS 1382
             K +      +      +  L +++    D G Y      +      DV     +  K  
Sbjct: 1387 GKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQ 1446

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            P  +    +  +S+   C    E     T + +  + +++  +  + ++ +  T+  +  
Sbjct: 1447 PVHREVQAQAGASTTLSC----EVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQ 1502

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
                +          E      S+   ++  + E K      +   + +  E      L+
Sbjct: 1503 QAGQA-------VAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLS 1555

Query: 1503 CIFGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            C      Q +VTWY+DGKKL  ++K   E                    Y C A    G+
Sbjct: 1556 CEVAQA-QTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GD 1610

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDK 1617
               S  + + +  V+    +   ++ +       T   E      EV WYK+G KL +  
Sbjct: 1611 QRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSS 1670

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASN---TAGTSSVEVTLKVYDKPSKPEGPVI 1674
            +  +     T  + +++  ++ + +Y+ EA     +      E+  ++ ++P + E P++
Sbjct: 1671 KVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRRE-PLV 1729

Query: 1675 MRE 1677
            ++E
Sbjct: 1730 VKE 1732



 Score =  161 bits (392), Expect = 1e-37
 Identities = 200/904 (22%), Positives = 364/904 (40%), Gaps = 67/904 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +  +P  F++  + +   EG+  +L C L  +    + W +KG E + D +   ++  D 
Sbjct: 3621 VRALPIKFTEGLRNEEATEGATAVLRCELSKMAP--VEW-WKGHETLRDGDRH-SLRQD- 3675

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
               C  L+I  +     G Y  +       A L +          P + IE L++    +
Sbjct: 3676 GARCE-LQIRGLVAEDAGEYLCMCGKERTSAMLTV-------RAMPSKFIEGLRNEEATE 3727

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKA 807
            G++  L  ++  +    + W K ++ ++      DGD HS+     + +++  G+  + A
Sbjct: 3728 GDTATLWCEL--SKAAPVEWRKGHETLR------DGDRHSLRQDGSRCELQIRGLAVVDA 3779

Query: 808  ENSE---GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
                   G   TSA +TV       A P  FI   +    +E  T  L   +++     +
Sbjct: 3780 GEYSCVCGQERTSATLTVR------ALPARFIEDVKNQEAREGATAVLQCELSK--AAPV 3831

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W + +E +   +  +   DG   EL I  + S  D+G+Y CV     G+    A +T+ 
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGL-SVADTGEYSCVC----GQERTSATLTVR 3886

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXX 983
              +  F + LQ S + EEG T  L+C+ S  T +  W     ++     RE   +G    
Sbjct: 3887 APQPVFREPLQ-SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                     D G   C    Q TS  L V      F+R+LQ  EV E   A L  E++  
Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRA 4005

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
             A V W +    + P   KY   + G   +L +R     D G+Y+C        A ++V 
Sbjct: 4006 GASVEWRKGSLQLFPCA-KYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVR 4064

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
               P+  TRLQ+ +   G+ A    +L+  +  A+V+W K+G E+      ++   G  +
Sbjct: 4065 VPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
            +L I+  +  D GEY+C  G  K  A L V EP +     L +   V A+ D   + E+ 
Sbjct: 4125 ELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVD-AEVTADEDVEFSCEVS 4183

Query: 1222 DE-TLDVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
                  V W  +   ++  E   + + D +  TL ++  T +D    +  L +  S+ +L
Sbjct: 4184 RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQL 4243

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
             V   E    I++  ++ ++  G D +              W +    ++  +    +++
Sbjct: 4244 TVRAPEV--TILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301

Query: 1340 SKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI--LEIDSSS 1396
              +   LT+ KV   DAG     +   C  ++ ++ VT        G  N+  LE   + 
Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSFHV-GTCS-SEAQLKVT-AKNTVVRGLENVEALEGGEAL 4358

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
                  +PE   ++ ++     +   +  E +  +N  +    ++NL+   S R    A 
Sbjct: 4359 FECQLSQPEVAAHTWLLDDEPVHTS-ENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAG 4417

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG-GVPQPKVTW 1515
            + V        T  +  ++  +++   + +PLKN           TC     VP  + +W
Sbjct: 4418 DMV--------TSAFLTVRGWRLE---ILEPLKNAAVRAGAQACFTCTLSEAVPVGEASW 4466

Query: 1516 YRDG 1519
            Y +G
Sbjct: 4467 YING 4470



 Score =  161 bits (390), Expect = 3e-37
 Identities = 157/735 (21%), Positives = 292/735 (39%), Gaps = 46/735 (6%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            + G+  +L C  VA  + ++ W   G+++     + + ++         L +    K   
Sbjct: 1087 EAGASAMLSCE-VAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRR----LVLPQAGKADA 1141

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            G Y+  A  +     L I        KE  Q +     +    G + +LS +V   P+  
Sbjct: 1142 GEYSCEAGGQRVSFHLHITEPKGVFAKE--QSVH--NEVQAEAGTTAMLSCEVA-QPQTE 1196

Query: 766  ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            +TW K+ K + +   +  +  G T  + + +  K  D G Y+ +A    G    S  + +
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKA-DAGEYSCEA----GGQRVSFQLHI 1251

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
             EP    A+  L  N   E+  +   +  L   V +     +TWY++ + +S S  +   
Sbjct: 1252 TEPKAVFAKEQLVHN---EVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIE 1307

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH--LQKSYET 940
              G   +LV+     + D+G+Y C     AG       + +   K  F K     +  + 
Sbjct: 1308 AAGCMRQLVVQQA-GQADAGEYTC----EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQA 1362

Query: 941  EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            E G    L C+ +       WY + K++S      +   G             D G   C
Sbjct: 1363 EAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC 1422

Query: 1000 IVKDQETSTMLVVKETIPEFIRKL---QDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
                Q  S  L V E    F ++    ++ + +      L  E+     +V+W +DG+ +
Sbjct: 1423 EAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKL 1482

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQ-- 1114
                +K   E  G  R+L ++       GEYSC    +  +  + V E P  +  + Q  
Sbjct: 1483 S-FSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAE-PKAVFAKEQPA 1540

Query: 1115 --NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
                +   G  AT   E+ +    V W+KDG ++  S+ +++   G  ++L + +    D
Sbjct: 1541 SREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQAD 1600

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF--ILVPANTDAYLTVEIPDETLDVTWY 1230
            AGEYSC+ G+ + +  L V EP + F    P    +   A   A L+ E+     +VTWY
Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWY 1660

Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
            K    +  + K  + +    R L++++  + +  EY+C           +++V E  P+I
Sbjct: 1661 KDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA--GGQQLSFRLQVAELEPQI 1718

Query: 1291 VD--YERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
             +    RE   +K   D+ L             W+ +   I++ K  + +    + +LT+
Sbjct: 1719 SERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTV 1778

Query: 1348 KKVENTDAGIYKLRL 1362
               +  D+ IY  R+
Sbjct: 1779 HGAQVLDSAIYSCRV 1793



 Score =  152 bits (369), Expect = 9e-35
 Identities = 142/641 (22%), Positives = 260/641 (40%), Gaps = 32/641 (4%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            + G+   L C  VA  + ++ W   G+++     + V            L +    + + 
Sbjct: 1639 EAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRR----LVVQQAGQAEA 1693

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            G Y+  A  ++    L +  +++    E P   EPL   +V++ E +IL+A +      T
Sbjct: 1694 GEYSCEAGGQQLSFRLQVA-ELEPQISERPCRREPL---VVKEHEDIILTATLATPSAAT 1749

Query: 766  ITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            +TW K+   +   K   T S GDTH++T+    +V D  +Y+ +   +EG       + V
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTV-HGAQVLDSAIYSCRV-GAEG---QDFPVQV 1804

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            EE   +      F    + +  +  GT+ L   ++      + W   N  +   +     
Sbjct: 1805 EEVAAK------FCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMV 1857

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             +G    L +  + +E D+G+Y C + +        A++T+ V +V        +   EE
Sbjct: 1858 AEGPVRSLTVLGLRAE-DAGEYVCESRDD----HTSAQLTVSVPRVVKFMSGLSTVVAEE 1912

Query: 943  GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            G     +C  S + V+  W+ +   +   +   I Q G             D G I    
Sbjct: 1913 GGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEA 1972

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
            +   +S  L V+E    F +KL+   V+E+    LEVE+     ++ W R+   + P KN
Sbjct: 1973 EGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKN 2032

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
              +    G   +L + N    D G + C   D+   A++TV      ++  LQ  +  + 
Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQ 2091

Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              AT E++L+  D    W +DG   Q      L + G    L +     +D+G    +  
Sbjct: 2092 GTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151

Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
                +A L V E  ++F+  L + ++        L  E+    +DV W K    +   + 
Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQD-VVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKT 2210

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
              + +    R+L I +C   DQ  Y C   DA+S+  +KV+
Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQ 2251



 Score =  138 bits (334), Expect = 2e-30
 Identities = 135/567 (23%), Positives = 235/567 (41%), Gaps = 35/567 (6%)

Query: 632  IPPTFSKKP---KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            + P  S++P   +   V E  DI+L   L       + WL  G EI   +    A + D 
Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            H     L +   +      Y+   V  EG+   P+  +++    +  +++EP+   +   
Sbjct: 1774 H----TLTVHGAQVLDSAIYSC-RVGAEGQ-DFPV--QVEEVAAKFCRLLEPVCGEL--- 1822

Query: 749  GESVILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            G +V L+ ++       +  C N   +  K     ++G   S+T+L   + +D G Y  +
Sbjct: 1823 GGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLG-LRAEDAGEYVCE 1881

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            + +      TSA +TV  P         F++    +  +E G       V+ + V ++ W
Sbjct: 1882 SRDDH----TSAQLTVSVPRVVK-----FMSGLSTVVAEEGGEATFQCVVSPSDV-AVVW 1931

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            +R+  ++ PSE    +  G +  L I+++  E D+G    +   + G SS  A + +   
Sbjct: 1932 FRDGALLQPSEKFAISQSGASHSLTISDLVLE-DAGQ---ITVEAEGASSSAA-LRVREA 1986

Query: 927  KVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             V F K L+     EE  +V LE + T      +W  N   ++   + EI  EG      
Sbjct: 1987 PVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D G   C   D +T   L V+      +R LQ  E +E+  A +EV+++    
Sbjct: 2046 LHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADV 2105

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            D  W RDG   +     +    RG +  L +      D G           +A + V EL
Sbjct: 2106 DGSWTRDGLRFQQGPTCH-LAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTEL 2164

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P      LQ+    +  K T E EL++ +  VRW KDG E++    + +   G  + L I
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            Y C+  D G Y C+  +++ +A + V+
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQ 2251



 Score =  134 bits (325), Expect = 2e-29
 Identities = 164/758 (21%), Positives = 285/758 (37%), Gaps = 49/758 (6%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  F K       +E   + L+C  V+ PE  + W   G ++ P +       +      
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG-- 2702

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L + +V     G YT    + E  A +  V  +  G      + + LK+M V +GES 
Sbjct: 2703 --LVVHDVSPEDAGLYTCHVGSEETRARVR-VHDLHVG------ITKRLKTMEVLEGESC 2753

Query: 753  ----ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
                +LS +   +P       K             G  + I +++     D G       
Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKY-ILVVREAAPSDAGEVVFSVR 2812

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
               G+   +++I  E P          I   ++  V     ++L   ++R   P + W +
Sbjct: 2813 ---GLTSKASLIVRERPAA-------IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLK 2861

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            + + I  S+      +G    LVI     + D+G+Y C     A KS+  A + ++ +  
Sbjct: 2862 DRKAIRKSQKYDVVCEGTMAMLVIRGASLK-DAGEYTCEVE--ASKST--ASLHVEEKAN 2916

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             F + L  + + EE  T +  C+T H  +T  W     E+      +  QEG        
Sbjct: 2917 CFTEELT-NLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTIS 2975

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D     C +   ++   L+V+      I  L+D +V+E   A     I+    + 
Sbjct: 2976 ALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEP 3035

Query: 1048 V-WERDGEIIKPKK-NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            V W  D   +   + N+ D +  G+   L +R  ++ D G       D+  +A + V E 
Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEK 3094

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P      L +  + +G   T   E +  D  V W KDG  ++ S   QL+ +G + +L I
Sbjct: 3095 PSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLI 3154

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
                L D+G Y CE G +  ++I+ V    + F   L +  ++     A L   +     
Sbjct: 3155 TGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA-ATLRCVLSSVAA 3213

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
             V W    +V+   +K++L  +     L++R     D   Y+C   D   TT   + V  
Sbjct: 3214 PVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGD--QTTSATLTVTA 3271

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             P + +   R      G+  TL  +  +A P    EW   S+ ++         D     
Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCELSKAAPV---EWRKGSETLRDGDRYCLRQDGAMCE 3328

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            L I+ +   DA  Y       CG      ++TI   P+
Sbjct: 3329 LQIRGLAMVDAAEYSC----VCGEERTSASLTIRPMPA 3362



 Score =  131 bits (316), Expect = 2e-28
 Identities = 147/691 (21%), Positives = 264/691 (38%), Gaps = 38/691 (5%)

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            E GT   ++         +TWY++ + +S S  +     G    LV+     + D+G+Y 
Sbjct: 1547 EAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEA-GQADAGEYS 1605

Query: 906  CVASNSAGKSSHGARVTIDVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYH 962
            C     AG       + +   KV F K     +  + E G +  L C+ +       WY 
Sbjct: 1606 C----KAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYK 1661

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK 1022
            + K++S      +   G             + G   C    Q+ S  L V E  P+   +
Sbjct: 1662 DGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISER 1721

Query: 1023 ---LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
                +   VKE +  IL   + + +A  V W +DG  I+  K +++   +G    L +  
Sbjct: 1722 PCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSK-RHETASQGDTHTLTVHG 1780

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138
              V D   YSC +  E     V V E+  +    L+      G   T   EL+   A V 
Sbjct: 1781 AQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVV 1840

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS-IN 1197
            W    ++++     Q+  +G  + L +     +DAGEY CE  +   +A LTV  P  + 
Sbjct: 1841 WRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
            F   L   +        +  V  P + + V W++  ++++ +EKF +       +L I  
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959

Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
               +D  + T     A S+  L+V   E P           ++  S VTL V+    P P
Sbjct: 1960 LVLEDAGQITVEAEGASSSAALRVR--EAPVLFKKKLEPQTVEERSSVTLEVELTR-PWP 2016

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               W  N+  +   K+ +   +     L +  V   D G +     ++   A + + +  
Sbjct: 2017 ELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQ 2076

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            +            E  ++++ +     +  G+ T     + +Q+  T   ++V+    T 
Sbjct: 2077 VRLVRGLQAVEAREQGTATMEVQLSHADVDGSWT--RDGLRFQQGPTCH-LAVRGPMHTL 2133

Query: 1438 TSIQNLKTNSS--YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
            T +  L+   S    F+A  V+          T    V+ E  +   +  +PL+++ T  
Sbjct: 2134 T-LSGLRPEDSGLMVFKAEGVH----------TSARLVVTELPV---SFSRPLQDVVTTE 2179

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526
             E + L C     P   V W +DG +L+  K
Sbjct: 2180 KEKVTLECELSR-PNVDVRWLKDGVELRAGK 2209



 Score =  126 bits (305), Expect = 5e-27
 Identities = 122/542 (22%), Positives = 224/542 (41%), Gaps = 23/542 (4%)

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G S  LS +V    +  +TW K+ K + +   +  ++ G T  + + +  +  D G Y+ 
Sbjct: 1549 GTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQA-DAGEYSC 1606

Query: 806  KAENSEGIAETSAVITVEEPTEENA-EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            KA    G    S  + V EP    A E P      +E+  +   +  L   V +     +
Sbjct: 1607 KA----GDQRLSFHLHVAEPKVVFAKEQPAH----REVQAEAGASATLSCEVAQAQT-EV 1657

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TWY++ + +S S  +     G    LV+     + ++G+Y C A     + S   +V   
Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA-GQAEAGEYSCEAGGQ--QLSFRLQVAEL 1714

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
              +++     ++    +E + +IL     T    +  W  +  EI      E   +G   
Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D  +  C V  +     + V+E   +F R L+    +      L  E++ 
Sbjct: 1775 TLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSP 1834

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
              A+VVW      ++  K ++     G +R L +      D GEY C  RD+  +A++TV
Sbjct: 1835 ACAEVVWRCGNTQLRVGK-RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTV 1893

Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
             V    + ++ L      +G +ATF+  ++  D  V WF+DG+ +Q S    ++  G   
Sbjct: 1894 SVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASH 1953

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
             L I D  L+DAG+ + E   +  +A L V E  + F  +L E   V   +   L VE+ 
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKL-EPQTVEERSSVTLEVELT 2012

Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
                ++ W +  + +   +   + ++  +  L++      D+  + C   D K+  KL V
Sbjct: 2013 RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTV 2072

Query: 1282 EV 1283
            E+
Sbjct: 2073 EM 2074



 Score =  122 bits (293), Expect = 1e-25
 Identities = 206/1051 (19%), Positives = 385/1051 (36%), Gaps = 70/1051 (6%)

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            K P+   V  G D  + C  +A+P   + WL   EE+V    ++++ E   H     L I
Sbjct: 425  KLPRKTAVRVG-DTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRH----TLTI 479

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSA 756
            +       G    +A    G+        +    K P Q  ++P+     R   SVILS 
Sbjct: 480  SQCCLEDVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVK--ARMESSVILSW 533

Query: 757  QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPK----KVKDEGVYTLKAENSE 811
                +    +T        K L T +    H    +  P+     V +EG +  +     
Sbjct: 534  SPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALN 593

Query: 812  GIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
               ++  +   E P   +  P L +    + +   E G +     +T     +  W+ + 
Sbjct: 594  SFGQSPYL---EFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLT--VASAGEWFLDG 648

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN--SAGKSSHGARVTIDVEKV 928
            + +  S     + D     L I  V + +     K VA+   S+ +    A   +   K 
Sbjct: 649  QALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKP 708

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                  +      E   ++ E  +    +  W  + + +S     E+             
Sbjct: 709  PAAAAREVLARLHEEAQLLAEL-SDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRD 767

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD---FEVKEKDVAILEVEINSETA 1045
                D G+ +C+ +    +  L V + +  F+ K       +      A  E E +    
Sbjct: 768  VARDDAGLYECVSRGGRIAYQLSV-QGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHV 826

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
             V W +DG  +     ++  E  G   +L     +  DEG YSC + ++S    + V E 
Sbjct: 827  HVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSE- 885

Query: 1106 PPEII---TRLQNQKVNK--GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
             P+++    +L  +K+    G  AT   E+ +    V W+KDG ++  S+ + +   G  
Sbjct: 886  -PKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCT 944

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTV 1218
            ++L +      DAGEYSCE G  + +  L V+EP + F         +   A   A L+ 
Sbjct: 945  RRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSC 1004

Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
            E+     +V WYK    +  + K  + +   +R L++++  + D  +Y+C     + + +
Sbjct: 1005 EVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFR 1064

Query: 1279 LKV-EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            L + E      K      E + + G+   L  +  A  Q    W  + K +         
Sbjct: 1065 LHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGME 1123

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
            +   +  L + +    DAG Y        G   V  ++ I +   P G   +   + S  
Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITE---PKG---VFAKEQSVH 1173

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
            N   +     G + ++   V   + + T +   K ++ +      +K   + R     V 
Sbjct: 1174 N---EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK-GCTRRLVVQQVG 1229

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTV----EKPLKN-ITTEPNEDIELTCIFGGVPQPK 1512
            + D  + S      +V  +  I  P      E+ + N + TE      L+C      Q +
Sbjct: 1230 KADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQA-QTE 1288

Query: 1513 VTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            VTWY+DGKKL  ++K   E                    Y C A    G    S  + + 
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLDVS 1344

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
            +   +    +   +K +     + T   E      EV WYK+G KL +  +  +     T
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
              + +++  ++ + +Y+ EA     + S++V
Sbjct: 1405 RRLVVQQACQADTGEYSCEAGGQRLSFSLDV 1435



 Score =  122 bits (293), Expect = 1e-25
 Identities = 150/720 (20%), Positives = 283/720 (39%), Gaps = 38/720 (5%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704
            + G+   L C  VA  + ++ W   G+++    +  V +E+   + C+  L +    +  
Sbjct: 1547 EAGTSATLSCE-VAQAQTEVTWYKDGKKL--SSSSKVRMEA---VGCTRRLVVQEAGQAD 1600

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y+  A ++     L +        KE P   E    +    G S  LS +V    + 
Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHRE----VQAEAGASATLSCEVA-QAQT 1655

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             +TW K+ K + +   +  ++ G T  + + +  +  + G Y+ +A    G  + S  + 
Sbjct: 1656 EVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQA-EAGEYSCEA----GGQQLSFRLQ 1710

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V E   + +E P    R + + VKE   I L A +      ++TW ++   I  S+    
Sbjct: 1711 VAELEPQISERPC---RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHET 1767

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
               G+   L +      +DS  Y C      G       V ++     F + L+     E
Sbjct: 1768 ASQGDTHTLTVHGAQV-LDSAIYSC----RVGAEGQDFPVQVEEVAAKFCRLLEPVCG-E 1821

Query: 942  EGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
             G TV L C+ S   +   W     ++      +++ EG             D G   C 
Sbjct: 1822 LGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881

Query: 1001 VKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
             +D  TS  L V    + +F+  L     +E   A  +  ++     VVW RDG +++P 
Sbjct: 1882 SRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPS 1941

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
            + K+   + G    L I +  + D G+ +      S +A + V E P     +L+ Q V 
Sbjct: 1942 E-KFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVE 2000

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            + +  T E+ELT+    +RW ++ + +    ++++  +G + +L +++    D G + CE
Sbjct: 2001 ERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCE 2060

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
              + K  A LTVE   +     L + +       A + V++    +D +W +     +  
Sbjct: 2061 TPDDKTQAKLTVEMRQVRLVRGL-QAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQG 2119

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKIVDYEREYR 1298
                L       TL +     +D      ++  A+   T  ++ V E P       ++  
Sbjct: 2120 PTCHLAVRGPMHTLTLSGLRPEDS---GLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV 2176

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
                  VTL  +    P  +  W+ +   ++  K    +      SLTI + E  D G+Y
Sbjct: 2177 TTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235



 Score =  115 bits (277), Expect = 1e-23
 Identities = 136/655 (20%), Positives = 244/655 (37%), Gaps = 46/655 (7%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSIT 790
            P     PL+ ++  + E V L  ++   P   + W K+   ++A  T +    G   S+T
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAV----------ITVEEPTE-----ENAE---- 831
            I + +   D+GVY   A +++  A               +  E+  E     ENAE    
Sbjct: 2224 IYRCE-FADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQ 2282

Query: 832  ------PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
                  P   +   ++    EK    L  +V+R     + W++ ++ + P        DG
Sbjct: 2283 LRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASA-QVRWFKGSQELQPGPKYELVSDG 2341

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
               +L+I++V +E D   Y C     AG     A+  ++ + +T V+ LQ      E   
Sbjct: 2342 LYRKLIISDVHAE-DEDTYTC----DAGDVKTSAQFFVEEQSITIVRGLQ-DVTVMEPAP 2395

Query: 946  VILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
               EC+TS       KW   K  +    +  + QEG               G +   V  
Sbjct: 2396 AWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGK 2455

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
              +S  LVV +      R L+    +E    +L  +       V W +D   + P + K+
Sbjct: 2456 SRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSE-KF 2514

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
                 G + +L I      D G Y C       + EVTV      +   LQ+ +  +   
Sbjct: 2515 KMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGW 2574

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            A+F  EL+  D  V W  +G  +   +  +++  G++  L +      DAG         
Sbjct: 2575 ASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKV 2634

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
              +A L V    + F   L +       T A L  E+ D    V W K    +  ++K+ 
Sbjct: 2635 STSARLEVRVKPVVFLKALDDLSAEERGTLA-LQCEVSDPEAHVVWRKDGVQLGPSDKYD 2693

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
             +     R L++   + +D   YTC +      T+ +V V +    I    +   +  G 
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHV--GSEETRARVRVHDLHVGITKRLKTMEVLEGE 2751

Query: 1304 DVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
              +   ++ +++   P   W V  K +      + +   +   L +++   +DAG
Sbjct: 2752 SCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805



 Score =  105 bits (253), Expect = 1e-20
 Identities = 83/355 (23%), Positives = 147/355 (41%), Gaps = 38/355 (10%)

Query: 501  PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            P+      AP+F+ +L+ +   DG  V F+C V G P P + WF+   +++    + +  
Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH--GSEMTVXXXXX 618
            D      L+I  V P D G + C+A+N+ G +S+  EL V+   +D+   ++ T      
Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236

Query: 619  XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL---------ECRLVAIPEPDIAWLF 669
                   +   EG   T  +    Q V+E  D+ +         + ++   P P + W  
Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296

Query: 670  KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
             G+ +    +I +  +  +H     L+I +V +   G Y     N  G A     L ++ 
Sbjct: 5297 DGQPLTASAHIRMTDKKILH----TLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352

Query: 730  GEKE-------------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
             ++              PP+++E      V++G S+  S +V G P PT+ W +      
Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERG 5412

Query: 777  AL---------PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             L            S    HS+ +L   + + +G YT  A N+ G A  SA + V
Sbjct: 5413 VLWIGPDTPGYTVASSAQQHSLVLLDVGR-QHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  104 bits (250), Expect = 2e-20
 Identities = 162/749 (21%), Positives = 289/749 (38%), Gaps = 66/749 (8%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            +EG +   +C +V+  +  + W   G  + P E  +++     H     L I+++     
Sbjct: 1911 EEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHS----LTISDLVLEDA 1965

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            G  TV A   EG AS    L+++   + P    + L+   V +  SV L  ++   P P 
Sbjct: 1966 GQITVEA---EG-ASSSAALRVR---EAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPE 2017

Query: 766  ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            + W +N     P K +   ++G  H + +L      D G +  +  + +    T A +TV
Sbjct: 2018 LRWTRNATALAPGKNVEIHAEGARHRL-VLHNVGFADRGFFGCETPDDK----TQAKLTV 2072

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            E            +   Q +  +E+GT  +  +++   V   +W R+        T    
Sbjct: 2073 E------MRQVRLVRGLQAVEAREQGTATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLA 2125

Query: 883  FDGENIELVITNVDSEIDSG-----------DYKCVASNSAGKSSHGAR--VTIDVEKVT 929
              G    L ++ +  E DSG             + V +      S   +  VT + EKVT
Sbjct: 2126 VRGPMHTLTLSGLRPE-DSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVT 2184

Query: 930  F----------VKHLQKSYETEEGKTVILECQ---TSHTVSTKWYHNKKEI-----SGMD 971
                       V+ L+   E   GKT+ +  Q    S T+    + ++            
Sbjct: 2185 LECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQS 2244

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
               +  +GR            D G I+ + ++ E+   L VKE     +R L+D    EK
Sbjct: 2245 SASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEK 2304

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
               +LE +++  +A V W +  + ++P   KY+    G  RKL I +    DE  Y+C  
Sbjct: 2305 HRGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150
             D   +A+  V E    I+  LQ+  V +   A FE E +       +W    + +Q   
Sbjct: 2364 GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGG 2423

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            ++ L  +G   +L +        G     VG S+ +A L V +  +  T  L E      
Sbjct: 2424 NVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPL-EPKTGRE 2482

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                 L+ +       V WYK  + +  +EKF +  + +   L I +    D   Y C  
Sbjct: 2483 LQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542

Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
              A S+T++ VE  E        + E   +  +  +  + ++       EW +N   +  
Sbjct: 2543 GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHE---DEEVEWSLNGMPLYN 2599

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
                + S   +  +L +K ++  DAGI +
Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVR 2628



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 119/564 (21%), Positives = 219/564 (38%), Gaps = 39/564 (6%)

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
            ++  V +G+   LS  V G P+P   W K+ + V   +      D   + +  +   K  
Sbjct: 245  RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            D G+YT  A N  G   +S ++ V EP    A P  F  R Q++ V+EK +   +  V +
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLVVVREP----AVP--FKKRLQDLEVREKESATFLCEVPQ 358

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P     W++    +  S       +G    L + NV ++ D   Y C       ++  G
Sbjct: 359  -PSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSAD-DDAVYIC-------ETPEG 409

Query: 919  ARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREII 976
            +R   ++  +   ++ L +      G T +   + +  V    W  N++E+       I 
Sbjct: 410  SRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAIS 469

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK-DVAI 1035
             EG             DVG +  +  D +TST   V       ++   D  VK + + ++
Sbjct: 470  AEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSV 529

Query: 1036 LEVEINSETADVVWERDGEIIKPKK-NKYDF---EKRGHIRKLYIRNTSVHDEGEYSCIL 1091
            +         +     DG +++ KK   Y +    +   +    +    V +EG +   +
Sbjct: 530  ILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRV 589

Query: 1092 RDESCTAEVTVVELP------PEIITR--LQNQKVNKGNKATFEIELTKGDALVRWFKDG 1143
               +   +   +E P      P++  R  L+  +  +G + TF ++LT   A   WF DG
Sbjct: 590  SALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLTVASA-GEWFLDG 648

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203
              ++ S+  ++  D  +  L I +      G     V N   ++I      +   T   P
Sbjct: 649  QALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKP 708

Query: 1204 -----EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
                   +L   + +A L  E+ D+   VTW K    +    K+ + +   +R L++R  
Sbjct: 709  PAAAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDV 768

Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVE 1282
              DD   Y CV    +   +L V+
Sbjct: 769  ARDDAGLYECVSRGGRIAYQLSVQ 792



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 108/524 (20%), Positives = 208/524 (39%), Gaps = 37/524 (7%)

Query: 1139 WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEE 1193
            W KDG  + +   H+      +   LKI  C   D G Y+C     VG +  + ++ V E
Sbjct: 271  WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
            P++ F  RL + + V     A    E+P  + +  W+K+++ +  + K+ +  +  +R L
Sbjct: 331  PAVPFKKRLQD-LEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
             +R  + DD   Y C   +   T     E+      +    R+  ++ G      V+  A
Sbjct: 390  TVRNVSADDDAVYICETPEGSRTV---AELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-A 445

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P     W+ N + +        S +    +LTI +    D G     +  +C     + 
Sbjct: 446  VPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF-MAGDC-QTSTQF 503

Query: 1374 NVTILDKP--SPPGKPNILEIDSSSINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-- 1428
             V+   KP   PP  P +     SS+ + W  P +     TI  Y+VE +++ T  WI  
Sbjct: 504  CVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRC 563

Query: 1429 -SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
               + +   + ++ ++    +++FR  A+N    S   E      +  +  +++P   K 
Sbjct: 564  HEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPL--KA 621

Query: 1488 LKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXX 1543
            ++ +   E    ++LT    G       W+ DG+ LK A + YE   +R           
Sbjct: 622  VQAVEGGEVTFSVDLTVASAG------EWFLDGQALK-ASSVYEIHCDRTRHTLTIREVP 674

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGI 1599
                   + F  +G +E+S  + ++  P +T +        +V     +E  + A +   
Sbjct: 675  ASLHGAQLKFVANG-IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSD- 732

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
                V W K+G  L    +Y +       V+ ++++ R  +  Y
Sbjct: 733  QAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLY 776



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 54/209 (25%), Positives = 96/209 (45%), Gaps = 15/209 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F  +PKA  V  G D  L C++V  P P ++W    + +       +A + D++    
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR--- 66

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----GEKEPPQVIEPLKSMIVRQG 749
            L I ++     G Y   A N  GEA   + L++       E+ P  ++ P  S+ VR+G
Sbjct: 67  -LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYT 804
                  +V G+PRP ++W K+ + +       +  +  G+  ++ I +  + +D G Y 
Sbjct: 125 SEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRI-RAARPRDGGTYE 183

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPP 833
           ++AEN  G A  +A + V+    + A  P
Sbjct: 184 VRAENPLGAASAAAALVVDSDAADTASRP 212



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 90/392 (22%), Positives = 152/392 (38%), Gaps = 27/392 (6%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVAT 567
           AP F+ +       +GS   F C+V G PRP ++W +    +      ++  ++    + 
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
           L IR   P D GT+   A+N  G AS+   L+V++  +D  S                 +
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228

Query: 628 IL--EGIPPT-FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
            +  EG P +  S   +   V EG    L C +   P+P+  W  K  ++V +    V  
Sbjct: 229 AMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVY 287

Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
           E     +  VLKI   K+   G YT  A N  G+    +++ ++  E   P   + L+ +
Sbjct: 288 EDAQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR--EPAVP-FKKRLQDL 342

Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEG 801
            VR+ ES     + V  P     W K    + A      + +G    +T+ +     D+ 
Sbjct: 343 EVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTV-RNVSADDDA 400

Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
           VY    E  EG + T A + V+            + +    T    G   +       PV
Sbjct: 401 VYI--CETPEG-SRTVAELAVQGN---------LLRKLPRKTAVRVGDTAMFCVELAVPV 448

Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVIT 893
             + W RN E +     +  + +G    L I+
Sbjct: 449 GPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 7/195 (3%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
           P+ +   K+ +V  G+   LS Q+VGNP P ++W K+ +PV A        DGD + +TI
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
           L    + D G Y  +A N+ G A  +  + V+       + P F+ R   I V+E     
Sbjct: 70  L-DLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128

Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDSEIDSGDYKCVAS 909
              RV  +P P+++W ++   +   +      +  GE   L I       D G Y+  A 
Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR-DGGTYEVRAE 187

Query: 910 NSAGKSSHGARVTID 924
           N  G +S  A + +D
Sbjct: 188 NPLGAASAAAALVVD 202



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 57/248 (22%), Positives = 106/248 (42%), Gaps = 8/248 (3%)

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTV 1102
            + VW++DG+++   +    +E       L I      D G Y+C    L  ++ ++ + V
Sbjct: 268  ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327

Query: 1103 VELPP-EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V  P      RLQ+ +V +   ATF  E+ +      WFK+ + +  S    +  +G ++
Sbjct: 328  VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTER 387

Query: 1162 KLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
            +L + +   DD   Y CE    S+  A L V+    N   +LP    V     A   VE+
Sbjct: 388  RLTVRNVSADDDAVYICETPEGSRTVAELAVQG---NLLRKLPRKTAVRVGDTAMFCVEL 444

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
                  V W + +  +    +  + ++  + TL I +C  +D  +   +  D +++T+  
Sbjct: 445  AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFC 504

Query: 1281 VEVVEFPP 1288
            V     PP
Sbjct: 505  VSAPRKPP 512



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 60/207 (28%), Positives = 95/207 (45%), Gaps = 22/207 (10%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT- 786
            T E + PQV+E L+ + V  G  +     +V G P P + W K+ +P+ A       D  
Sbjct: 5254 TDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKK 5313

Query: 787  --HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV---EEPTEENAE-------PPL 834
              H++ I+   + +D G Y     N+ G A +SA + V   +EP E+ A        PP 
Sbjct: 5314 ILHTLEIISVTR-EDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-----IISP-SETITQNFDGENI 888
             + RF    VK+  +I    +V   PVP++ W R         I P +   T     +  
Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKS 915
             LV+ +V  +   G Y C+ASN+AG++
Sbjct: 5433 SLVLLDVGRQ-HQGTYTCIASNAAGQA 5458



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 11/194 (5%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
            PP   E L       GE+V L+ +V G P+P I+W K+ K V+  P      D D     
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            IL      D G Y   A ++ G   T   I V+        PP F+N+ +     E    
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ-------VPPRFVNKVRASPFVEGEDA 6125

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            +    +   P P I WY++  +++      T +     + +++    S+ D G Y+C   
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185

Query: 910  NSAGKSSHGARVTI 923
            N  G +   A + I
Sbjct: 6186 NRLGSARASAELRI 6199



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568
            P FV K+R     +G   QF C +EG P PQI W++  A++     FQ   +    +  L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
            VIR    ED G + C   N  G A ++ EL +++P+
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPM 6203



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 9/188 (4%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXX 1536
            P  E+ L + T E  E ++L C   G P+P ++WY+DGK ++           +      
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y C A +  G   T   + +Q  P     N+        G++   T  I
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQFTCTI 6131

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTS 1654
            EG P P++ WYK+G  L    ++   ++ ++   V+ I+   +     Y  E  N  G++
Sbjct: 6132 EGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSA 6191

Query: 1655 SVEVTLKV 1662
                 L++
Sbjct: 6192 RASAELRI 6199



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 57/221 (25%), Positives = 89/221 (40%), Gaps = 26/221 (11%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           S AP F+ + +      G      CQ+ G P PQ++W +    +     F++  D D + 
Sbjct: 7   SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LY 65

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
            L I ++   D+G + C A+NA G A +   L V+A  +   +E                
Sbjct: 66  RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--CAEQA-------------- 109

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
                  P F  +P +  V EGS+    CR+   P P ++W   G  +   +   V +E 
Sbjct: 110 -------PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEE 162

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
                 S L+I   +    GTY V A N  G AS    L +
Sbjct: 163 LGE--ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 7/156 (4%)

Query: 1597 EGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            E +P  E  WY NG  ++ +D ++ +T       + ++  +  H+ + T    +   ++ 
Sbjct: 4457 EAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASAR 4516

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            + V L + D P   E  V+ R  S  +VT+ W  P+ DGG  L  Y +E  E    +W  
Sbjct: 4517 LTV-LGLPDPPEDAE--VVAR--SSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRL 4571

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
              ++    E   +  L     Y FRV A  PVG  E
Sbjct: 4572 CHELVPGPEC-VVDGLAPGETYRFRVAAVGPVGAGE 4606



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T QFE  +EG P+P +TW++ +  +  S        +    +LV+R V  +DAG +TC
Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTYSLVLRHVASKDAGVYTC 6429

Query: 584  VAKNAAGFASSTTELIV 600
            +A+N  G      EL+V
Sbjct: 6430 LAQNTGGQVLCKAELLV 6446



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 11/221 (4%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIE 889
            PP F     + T +   T+KL  RVT  P P I+WY++ + +   P   + ++ DG +  
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG-SCA 6071

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            L++ ++   +DSG Y C A+++AG  S   ++ + V    FV  ++ S    EG+     
Sbjct: 6072 LILDSLTG-VDSGQYMCFAASAAGNCSTLGKILVQVPP-RFVNKVRAS-PFVEGEDAQFT 6128

Query: 950  C--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX--XXXXXXXXXXXDVGVIKCIVKDQE 1005
            C  + +     +WY +   ++  +  + + E R              D+G+ +C + ++ 
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
             S     +  I   + + Q+   +E+ VA +E +   E AD
Sbjct: 6189 GSARASAELRIQSPMLQAQEQCHREQLVAAVE-DTTLERAD 6228



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 8/134 (5%)

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
            T    T +      A PP      +++  +  GT +  A +  +P PS+TWY+++  +  
Sbjct: 6340 TQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVD 6399

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKV 928
            S  ++Q  +G    LV+ +V S+ D+G Y C+A N+ G+    A + +       D EK 
Sbjct: 6400 STRLSQQQEGTTYSLVLRHVASK-DAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 6458

Query: 929  TFVKHLQKSYETEE 942
            +  + L   YE +E
Sbjct: 6459 SHRRKLHSFYEVKE 6472



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 27/94 (28%), Positives = 48/94 (51%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F E+L       G TV+  C+V G P+P I+W++    ++      +  D D    L+
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +  +   D+G + C A +AAG  S+  +++V+ P
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 11/197 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F ++      + G  + L CR+   P+P I+W   G+ +  D +  + IE D    C
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HILIE-DPDGSC 6070

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +++ + ++     G Y   A +  G  S    + ++     PP+ +  +++    +GE  
Sbjct: 6071 ALI-LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV----PPRFVNKVRASPFVEGEDA 6125

Query: 753  ILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH-SITILKPKKVKDEGVYTLKAE 808
              +  + G P P I W K+   +       T S+  +   + +++    +D G+Y  +  
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185

Query: 809  NSEGIAETSAVITVEEP 825
            N  G A  SA + ++ P
Sbjct: 6186 NRLGSARASAELRIQSP 6202



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 3/119 (2%)

Query: 815  ETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            ET A +   EP      +   P+F+   Q   V++   +     VT  P+PS+ W+++ +
Sbjct: 5105 ETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK 5164

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            ++   +    N D +    +I       D G Y+C+A NS G SS  A + +D+    +
Sbjct: 5165 LLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDY 5223



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 69/334 (20%), Positives = 125/334 (37%), Gaps = 24/334 (7%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            +Q   P+F           G  ++ EC V      +  W +    +   +   +    D 
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              +L+I  +   DAG +TC   N  G  + +  ++V       GSE              
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS------GSESEAESSSGGELDDA 5006

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLEC-RLVAIPEPDIAW-LFKGEE---IVPDEN 679
                   +   F  K  A+  DE  ++ L      A PE    W  ++ +E    +  E 
Sbjct: 5007 FRRAARRLHRLFRTKSPAEVSDE--ELFLSADEGPAEPEEPADWQTYREDEHFICIRFEA 5064

Query: 680  ISVA---IESDMHMYCSVLKITNVKKFQEGTYTV-VAVNREGEASL--PIVLKIKTGEKE 733
            ++ A   +     M+ ++     +K  ++G   V + +++E  A +  P  L        
Sbjct: 5065 LTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLLTSDA 5124

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSI 789
             P  +  L++  V+ G  V     V G P P++ W K+ K ++     +  +     H +
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             I+      D GVY   AENS G++ T A + V+
Sbjct: 5185 -IITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 28/87 (32%), Positives = 39/87 (44%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP F+ +L  +    G +V   CQV   P  Q TW +  A ++ S    +     N   L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASST 595
             I  V  ED G +TC   NA G  ++T
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 9/138 (6%)

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSD 783
            I T    PP +   ++ +  + G +    A + G+P+P++TW K++  +     L  + +
Sbjct: 6349 IDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQE 6408

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTEENAEPPLFINRF 839
            G T+S+ +L+    KD GVYT  A+N+ G     A + V     EP  E       ++ F
Sbjct: 6409 GTTYSL-VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSHRRKLHSF 6467

Query: 840  QEITVK-EKGTIKLVARV 856
             E+  +  +G    V RV
Sbjct: 6468 YEVKEEIGRGVFGFVKRV 6485



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 6/118 (5%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHE 1924
            P  P +  V   +S +VTL W  P S+GG  +  Y +E K      W      V G   E
Sbjct: 4523 PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGP--E 4580

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL-EKHATVPSPPTAPLEIRMVGS 1980
              ++ +   +   FR++A   VG   P    Q+VRL E    VP  P+AP E R V +
Sbjct: 4581 CVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAP-ESRQVAA 4637



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 35/155 (22%), Positives = 57/155 (36%), Gaps = 4/155 (2%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVV 1284
            ++WYK    ++      LI D      LI+   T  D  +Y C    A    + L   +V
Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343
            + PP+ V+  R      G D       +  P P   W  +  ++      +   + +S  
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164

Query: 1344 -SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              L I+     D G+Y+  L N  G A     + I
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 52/215 (24%), Positives = 81/215 (37%), Gaps = 16/215 (7%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP+    L +     G        +T     ++ W+KDG  +Q   H  L  D       
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 1165 IYDCDLD-DAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
            I D     D+G+Y C      GN S    IL    P     +R   F+      DA  T 
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFV---EGEDAQFTC 6129

Query: 1219 EIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAKS 1275
             I       + WYK  +++    KF  +S+ +     L+IR  +++D   Y C L++   
Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189

Query: 1276 TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTL 1307
            + +   E+    P +   E   RE  +    D TL
Sbjct: 6190 SARASAELRIQSPMLQAQEQCHREQLVAAVEDTTL 6224



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 15/180 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+ + + F V     A L  +I  + T  V WE+D + +     ++   + G + +L 
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLAQDGDLYRLT 68

Query: 1076 IRNTSVHDEGEYSCILRDE----------SCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125
            I + ++ D G+Y C  R+              AE    E  P  + R  + +V +G++AT
Sbjct: 69   ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128

Query: 1126 FEIELTKGD-ALVRWFKDGSEIQFSNHIQLTID--GKKQKLKIYDCDLDDAGEYSCEVGN 1182
            F   +       V W KDG  +   +  ++ ++  G+   L+I      D G Y     N
Sbjct: 129  FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAEN 188



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 15/201 (7%)

Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
            L  P+  +V    DA L+ +I  + T  V+W K +  +    +F L  D     L I   
Sbjct: 13   LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDL 72

Query: 1259 TEDDQCEYTC----VLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
               D  +Y C     + +A +   L+V+      E  P  +      R++ GS+ T    
Sbjct: 73   ALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCR 132

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                P+P   W  + + + +    +  ++   ++++L I+     D G Y++R EN  G 
Sbjct: 133  VGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGA 192

Query: 1369 ADVEMNVTI----LDKPSPPG 1385
            A     + +     D  S PG
Sbjct: 193  ASAAAALVVDSDAADTASRPG 213



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            +    L PK   +  +V   C     P+  + W++    + PS+ F+M  +   +A L I
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQ-MAELRI 2527

Query: 571  REVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
              + P DAG + C     AG A S+TE+ VEA
Sbjct: 2528 LRLMPADAGVYRC----QAGSAHSSTEVTVEA 2555



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/90 (30%), Positives = 41/90 (45%)

Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
            PE   V A  D  L +E+  E  +V W+K    I+   +F ++S  +++ L+I+  T +D
Sbjct: 4630 PESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAED 4689

Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292
            Q EY C L             V   P  VD
Sbjct: 4690 QGEYHCGLAQGSICPAAATFQVALSPASVD 4719



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNK-ATFEIELTKGDALVR--WFKDGSEIQF 1148
            R++  T   T     P+++  L++ +V  G + A F++++ KG    R  WFKDG  +  
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV-KGYPAPRLYWFKDGQPLTA 5303

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            S HI++T       L+I     +D+G+Y+  + N+
Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 4/79 (5%)

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            +DV+ LE+E+ +E  +V+W +  E I+P   +++   +G  + L I+  +  D+GEY C 
Sbjct: 4639 EDVS-LELEVVAEAGEVIWHKGMERIQP-GGRFEVVSQGRQQMLVIKGFTAEDQGEYHCG 4696

Query: 1091 LRDES-CTAEVTV-VELPP 1107
            L   S C A  T  V L P
Sbjct: 4697 LAQGSICPAAATFQVALSP 4715



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024
            +P PP    E+    S+ V  SW  P  DGG  L GY + +++     W    ++ V   
Sbjct: 4522 LPDPPE-DAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHEL-VPGP 4579

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
            +  +  L+   TY  R+ A   +G  EP+
Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPV 4608



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK-KQKL 1163
            P  +T LQNQ+V  G   +F+  +T G  +  VRWFKDG  ++  +H  +  D +   +L
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT-GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 1164 KIYDCDLDDAGEYSCEVGNS 1183
             I      D G Y C   NS
Sbjct: 5185 IITAVVPADMGVYRCLAENS 5204



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 1/94 (1%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
           P F+ R +   V       L  ++  NP P ++W ++ + ++         DG+   L I
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            ++    DSG Y C A N+ G++     + +D E
Sbjct: 70  LDLALG-DSGQYVCRARNAIGEAFAAVGLQVDAE 102



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 41/187 (21%), Positives = 67/187 (35%), Gaps = 15/187 (8%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544
            K       +D  L+C   G P P+V+W +D + +        A   +             
Sbjct: 17   KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGD 76

Query: 1545 XXXYKCIAFNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
               Y C A N  GE   +  + +       +Q P   +    I+ +   G E      + 
Sbjct: 77   SGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVRE--GSEATFRCRVG 134

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            G P P V W K+G +L       +  +E  + S +RI+  +      Y + A N  G +S
Sbjct: 135  GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAAS 194

Query: 1656 VEVTLKV 1662
                L V
Sbjct: 195  AAAALVV 201



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 2/102 (1%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            IL  +PP F  K +A    EG D    C +   P P I W   G  +          E  
Sbjct: 6102 ILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
              +   VL I    K   G Y    VNR G A     L+I++
Sbjct: 6162 SGLL--VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 38/164 (23%), Positives = 62/164 (37%), Gaps = 7/164 (4%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYT 1644
            +G    +   +   P  +  W K+G  LE+     I+ T +   ++ I  +       YT
Sbjct: 7476 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 7535

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
               SN  GT +    L+  ++PS    P I  E+  + V + WKP    G +      I 
Sbjct: 7536 CSVSNALGTVTTTGVLRKAERPSSSPCPDI-GEVYADGVLLVWKPVESYGPVTY----IV 7590

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
            +   +   W  +A    D   Y   KL+    Y FR    +  G
Sbjct: 7591 QCSLEGGSWTTLASDIFDC-CYLTSKLSRGGTYTFRTACVSKAG 7633



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%)

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P + ++ ED++ +   G      A+IEG P P V WYK+  +L +    +   +  T  +
Sbjct: 6357 PSMQVTIEDVQAQ--TGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 6414

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
             ++ +    +  YT  A NT G    +  L V    ++P+
Sbjct: 6415 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPD 6454



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-- 1653
            ++G P P + W+K+G  L       +T K+    + I  + R  S +Y    SN  G   
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343

Query: 1654 SSVEVTLKVYDKP-SKPEGPV 1673
            SS  + ++  D+P  KP   V
Sbjct: 5344 SSARLLVRGPDEPEEKPASDV 5364



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 21/103 (20%), Positives = 43/103 (41%), Gaps = 4/103 (3%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            + + ++ T  Y+ I     + P+++  ++++  +     +   I  G PQP VTWY+D  
Sbjct: 6336 VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSV 6395

Query: 1521 KLKTAKATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEV 1559
            +L  +    + +                   Y C+A N  G+V
Sbjct: 6396 QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQV 6438



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  +TR +   V+ G  AT   ++       V W KD   +      +L  DG   +L I
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 1166 YDCDLDDAGEYSCEVGNS 1183
             D  L D+G+Y C   N+
Sbjct: 70   LDLALGDSGQYVCRARNA 87



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 1582 QKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRS 1638
            Q  +V D + V+   V+ G P P V W+K+G  LE D  Y I   ++    + I  +  +
Sbjct: 5133 QNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPA 5192

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV 1662
                Y   A N+ G SS +  L+V
Sbjct: 5193 DMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 38/170 (22%), Positives = 65/170 (38%), Gaps = 6/170 (3%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKL 1360
            G  VTL     A P     W  +   ++       S   K+  L TI  V   D G+Y  
Sbjct: 7477 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 7536

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
             + N  G       +   ++PS    P+I E+ +  + + W   E+ G  T   Y+V+  
Sbjct: 7537 SVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVT---YIVQC- 7592

Query: 1421 EIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             ++   W ++  +I         L    +Y FR   V++  +   S  +E
Sbjct: 7593 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSE 7642



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 2/73 (2%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            +F++ L      +  T+  +C+V   P   + W +    + PS  +   +       LV+
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVV 2705

Query: 571  REVFPEDAGTFTC 583
             +V PEDAG +TC
Sbjct: 2706 HDVSPEDAGLYTC 2718



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 5/104 (4%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSIT 790
            P  +  L    V  G+SV L+ QV   P    TW K+  P+    + L + +  +   +T
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            IL     +D GVYT    N+ G   T+ V+   E    +  P +
Sbjct: 7523 IL-VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI 7565



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 509  API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            AP+ F+ +L+ +   +G T    C++       + W + +  + P   +QM   D   A 
Sbjct: 3977 APVRFLRELQHQEVDEGGTAHLCCELSR-AGASVEWRKGSLQLFPCAKYQMV-QDGAAAE 4034

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFAS 593
            L++R V  EDAG +TC   +    AS
Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMAS 4060



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 38/182 (20%), Positives = 71/182 (39%), Gaps = 14/182 (7%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYEN---RXXXXXXXXXXX 1543
            +  T    +   L+C   G P+P+  W +DG+ +   +    YE+               
Sbjct: 245  RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP- 1602
                Y C A N  G+  +S +V + ++P +        Q  +V ++   T + E +P P 
Sbjct: 305  DRGLYTCTASNLVGQTYSSVLV-VVREPAVPFKKR--LQDLEVREKESATFLCE-VPQPS 360

Query: 1603 -EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY---TIEASNTAGTSSVEV 1658
             E  W+K   +L    +Y I  +     + ++ +     + Y   T E S T    +V+ 
Sbjct: 361  TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQG 420

Query: 1659 TL 1660
             L
Sbjct: 421  NL 422



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
            ++++V  G   + E+E+      V W K    IQ     ++   G++Q L I     +D 
Sbjct: 4631 ESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQ 4690

Query: 1174 GEYSCEVG-NSKCTAILTVE 1192
            GEY C +   S C A  T +
Sbjct: 4691 GEYHCGLAQGSICPAAATFQ 4710



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            ++  + G P PE +W K+G  +   + + +    ++  V++I   K+S    YT  ASN 
Sbjct: 257  LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316

Query: 1651 AGTSSVEVTLKVYDKPSKP 1669
             G +   V L V  +P+ P
Sbjct: 317  VGQTYSSV-LVVVREPAVP 334



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F+  L      +G    F+C V       + WFR  A+++PS+ F +     +  +L I 
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGAS-HSLTIS 1958

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
            ++  EDAG  T     A G +SS    + EAP+
Sbjct: 1959 DLVLEDAGQITV---EAEGASSSAALRVREAPV 1988



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            V+F C+V       + W  Q   ++ ++  ++   D  + TL ++ V PEDAGT +    
Sbjct: 4176 VEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLG 4235

Query: 587  NAAGFASSTT---ELIVEAPLSD 606
            N A  A  T    E+ +  PL D
Sbjct: 4236 NHASSAQLTVRAPEVTILEPLQD 4258



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 2/144 (1%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKK-QKLK 1164
            P  +  L ++ V  G   T   +++   A    W KDG+ ++ S+ + ++   K  Q L 
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I     +D G Y+C V N+  T   T            P   +     D  L V  P E+
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 7582

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDV 1248
                 Y  +  +E     TL SD+
Sbjct: 7583 YGPVTYIVQCSLEGGSWTTLASDI 7606



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 20/81 (24%), Positives = 35/81 (43%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P F+    + TV    ++ L  +V+  P    TW ++   +  S  +  +   +N +L+ 
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 893  TNVDSEIDSGDYKCVASNSAG 913
              V    D G Y C  SN+ G
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALG 7543


>UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin -
            Aedes aegypti (Yellowfever mosquito)
          Length = 924

 Score =  190 bits (462), Expect = 5e-46
 Identities = 191/746 (25%), Positives = 313/746 (41%), Gaps = 81/746 (10%)

Query: 496  PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII--KPS 553
            PV E    +   +AP F++K   +   DG  + FECQ++  P+PQI W   + +I   P 
Sbjct: 104  PVDEPVEKQIDGLAPTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPR 163

Query: 554  QDFQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
              F++  D     ATL +  V  ED+G +   AKN  G +S+T  L  ++       E+ 
Sbjct: 164  HKFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDS------EEVP 217

Query: 613  VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672
            V                +G  P F+++P  +  D+G +I+ ECR +  P+P   W    E
Sbjct: 218  VPA--------------DGFKPAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVYHE 263

Query: 673  --EIVPDENISVAIESDM-HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL---- 725
              E+      S   E D  H Y     I +VK+   G Y VVA N+ G++S  I L    
Sbjct: 264  KNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQLDRGVYNVVAKNKHGDSSAIINLNFDS 323

Query: 726  --KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KA 777
              KI   E +PP+   P K  I ++GE + +   +   P   ITW    + +      K 
Sbjct: 324  SAKIVNPEGKPPRF--PQKPTISQKGEVLSMECILEALPVADITWFHGTETITDGERFKI 381

Query: 778  LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE--PPL 834
            L      DT+ +T+ +      D G+Y   A N  G  E++A IT+     EN     P 
Sbjct: 382  LRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFG--ESNAHITLNFKANENDRGFAPS 439

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI---TQNFDGENIELV 891
            F+ + + I  K    I +  R    P P++ W R  + +  S  +    +  D +  EL 
Sbjct: 440  FVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELT 499

Query: 892  ITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK---HLQKSY--ETEEGKT 945
            +   D S  D G Y CV SN  G+SS    + I+ E+ +       ++K +    + GK 
Sbjct: 500  LNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKL 559

Query: 946  VILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX----XXXDVGVIKC 999
            V +EC  +T       W    + I      +I                     D G  KC
Sbjct: 560  VRMECKVKTDLKPDITWTREGRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKC 619

Query: 1000 IVKD--QETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEI 1055
             +K+   E +  L++  E +P    K +     +K  A +E  + S    + +W ++  +
Sbjct: 620  NIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKRTASIECAVASRFKPECIWMKETTV 679

Query: 1056 IKPKKN---KYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL------ 1105
            IK       K +  ++G    KL I   S  D G Y  + +++   A   V+E+      
Sbjct: 680  IKETHRHMIKIEETRQGEFSVKLNITELSEADFGAYKLVAKNDKGQATSQVIEIKDIVFE 739

Query: 1106 -PPE----IITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDG 1158
             PP     I  +L++ +V++G   T  + L   D    V W K+ + ++ S  +     G
Sbjct: 740  KPPPTKPIIDPKLKDVEVDEGGNLTLAVGLVHPDRHFKVYWMKNKTILKTSETVIQEFSG 799

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSK 1184
            +  KL + +C ++DAG Y   + N +
Sbjct: 800  RMAKLTVKNCTVEDAGTYKVSISNEQ 825



 Score =  174 bits (423), Expect = 3e-41
 Identities = 201/882 (22%), Positives = 377/882 (42%), Gaps = 112/882 (12%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ----DFQMYY 560
            +   AP F +K + +   DG+ + FECQ+   P+P I W+R   ++  +       Q + 
Sbjct: 3    DHDFAPSFTQKPQLRQEDDGNRLVFECQLIAKPKPAIEWYRSEELLSQNARTKFKIQSFG 62

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
            ++     L + +V   DAG +   AKN  G  S++  L   +P+ +   +          
Sbjct: 63   ENKYFVVLELDDVIDTDAGLYKVKAKNRMGEVSASINLNF-SPVDEPVEKQ--------- 112

Query: 621  XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
                    ++G+ PTF KKP  Q  ++G  ++ EC++ A P+P I W    + I      
Sbjct: 113  --------IDGLAPTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRH 164

Query: 681  SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIE 739
               +++D  +Y + L++ NV     G Y V A N  GE+S  I L   + E   P    +
Sbjct: 165  KFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDSEEVPVPADGFK 224

Query: 740  P--LKSMIVRQ---GESVILSAQVVGNPRPTITWC----KNNKPVKA-LPTKSDGD-THS 788
            P   +  + RQ   G++++   + +G+P+PT TW     KN   +     ++++ D  H 
Sbjct: 225  PAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHC 284

Query: 789  ITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRF-QEIT 843
              I   ++  K  D GVY + A+N  G  ++SA+I +  + + +   P     RF Q+ T
Sbjct: 285  YLIRFTIRDVKQLDRGVYNVVAKNKHG--DSSAIINLNFDSSAKIVNPEGKPPRFPQKPT 342

Query: 844  VKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEI- 899
            + +KG  + +   +   PV  ITW+   E I+  E   I +     +  L+   +     
Sbjct: 343  ISQKGEVLSMECILEALPVADITWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTA 402

Query: 900  -DSGDYKCVASNSAGKSSHGARVTIDVE--------KVTFVKHLQKSYETEEGKTVILE- 949
             D G Y+C A N  G+S+  A +T++ +          +FV+   K    + G  + ++ 
Sbjct: 403  NDGGIYRCHAFNPFGESN--AHITLNFKANENDRGFAPSFVEK-PKIIPNKLGTLITMKC 459

Query: 950  -CQTSHTVSTKWYHNKKEIS-----GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             C++    + KW   K+E+       ++ + + ++              D G   C++ +
Sbjct: 460  RCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISN 519

Query: 1004 Q--ETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERD 1052
            +  E+S  L +         +  P F+ K     +    +  +E ++ ++   D+ W R+
Sbjct: 520  EFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKLVRMECKVKTDLKPDITWTRE 579

Query: 1053 GEIIKPK---KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELP 1106
            G II+     K     EK  +   L +++    D G Y C +++   E     +  +E+ 
Sbjct: 580  GRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIV 639

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQ-- 1161
            P  + + + + V    K T  IE            W K+ + I+ ++   + I+  +Q  
Sbjct: 640  P--VIKEKPKLVTNVKKRTASIECAVASRFKPECIWMKETTVIKETHRHMIKIEETRQGE 697

Query: 1162 ---KLKIYDCDLDDAGEYSCEVGNSKCTAI--------LTVEEPSINFTLRLPEFILVPA 1210
               KL I +    D G Y     N K  A         +  E+P     +  P+   V  
Sbjct: 698  FSVKLNITELSEADFGAYKLVAKNDKGQATSQVIEIKDIVFEKPPPTKPIIDPKLKDVEV 757

Query: 1211 NTDAYLTVEI----PDETLDVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQC 1264
            +    LT+ +    PD    V W K K++++ +E  T+I +   R   L ++ CT +D  
Sbjct: 758  DEGGNLTLAVGLVHPDRHFKVYWMKNKTILKTSE--TVIQEFSGRMAKLTVKNCTVEDAG 815

Query: 1265 EYTCVLLDAKST--TKLKVEVVEFP--PKIVDYEREYRIKRG 1302
             Y   + + + +  ++ KVE  + P  PKI++  +E   K+G
Sbjct: 816  TYKVSISNEQQSDESEAKVEEAKKPEVPKIME-TKEPEPKKG 856



 Score =  148 bits (358), Expect = 2e-33
 Identities = 185/841 (21%), Positives = 346/841 (41%), Gaps = 95/841 (11%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692
            P+F++KP+ +  D+G+ ++ EC+L+A P+P I W    E +  +      I+S   + Y 
Sbjct: 8    PSFTQKPQLRQEDDGNRLVFECQLIAKPKPAIEWYRSEELLSQNARTKFKIQSFGENKYF 67

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---- 748
             VL++ +V     G Y V A NR GE S  I L     ++   + I+ L    +++    
Sbjct: 68   VVLELDDVIDTDAGLYKVKAKNRMGEVSASINLNFSPVDEPVEKQIDGLAPTFIKKPSIQ 127

Query: 749  ----GESVILSAQVVGNPRPTITWCKNNKPVKALP-----TKSDGDTHSITI-LKPKKVK 798
                G+ +I   Q+  +P+P I W  N+K +   P      ++DG  +  T+ +     +
Sbjct: 128  QENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFATLEVDNVTFE 187

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEP-----PLFINRFQEITVKEKGTIKLV 853
            D G Y + A+N  G  E+SA I++   +EE   P     P F  R       +   I   
Sbjct: 188  DSGKYKVTAKNELG--ESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSDDGKNIVFE 245

Query: 854  ARVTRNPVPSITW---YRNNEIISPSETITQNFDGEN----IELVITNVDSEIDSGDYKC 906
             R   +P P+ TW   +  NE+       ++  + +N    I   I +V  ++D G Y  
Sbjct: 246  CRCIGDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDV-KQLDRGVYNV 304

Query: 907  VASNSAGKSSHGARVTIDVE-KVTFV-----KHLQKSYETEEGKTVILEC--QTSHTVST 958
            VA N  G SS    +  D   K+        +  QK   +++G+ + +EC  +       
Sbjct: 305  VAKNKHGDSSAIINLNFDSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECILEALPVADI 364

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXX-----XXXDVGVIKCIVKDQ--ETSTMLV 1011
             W+H  + I+  +  +I+++                   D G+ +C   +   E++  + 
Sbjct: 365  TWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFGESNAHIT 424

Query: 1012 V--------KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNK 1062
            +        +   P F+ K +    K   +  ++    S+    V W R  + +K   NK
Sbjct: 425  LNFKANENDRGFAPSFVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVK-SSNK 483

Query: 1063 YDFEKRGHIRKLY-----IRNTSVHDEGEYSCILRDE----SCTAEVTV------VELPP 1107
               E +      Y     I++ S  D G YSC++ +E    S T  + +       +  P
Sbjct: 484  VALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAP 543

Query: 1108 EIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ----K 1162
              + +     ++ G     E ++ T     + W ++G  IQ +  +++T+  +K      
Sbjct: 544  IFVEKPHIVSLDNGKLVRMECKVKTDLKPDITWTREGRIIQETTKLKITMTAEKDVYHIS 603

Query: 1163 LKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
            L + D   +D+G Y C + N   +  A L +    +      P+ +       A +   +
Sbjct: 604  LVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKRTASIECAV 663

Query: 1221 PDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIR-KCTEDDQCEYTCVLLDAKS-- 1275
                  +  W K+ +VI++T +  + I + ++    ++   TE  + ++    L AK+  
Sbjct: 664  ASRFKPECIWMKETTVIKETHRHMIKIEETRQGEFSVKLNITELSEADFGAYKLVAKNDK 723

Query: 1276 ------TTKLKVEVVEFPPK---IVDYE-REYRIKRGSDVTLLVDYQAFPQPNDE--WIV 1323
                    ++K  V E PP    I+D + ++  +  G ++TL V     P  + +  W+ 
Sbjct: 724  GQATSQVIEIKDIVFEKPPPTKPIIDPKLKDVEVDEGGNLTLAVGL-VHPDRHFKVYWMK 782

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            N  I+K  +        + A LT+K     DAG YK+ + N     + E  V    KP  
Sbjct: 783  NKTILKTSETVIQEFSGRMAKLTVKNCTVEDAGTYKVSISNEQQSDESEAKVEEAKKPEV 842

Query: 1384 P 1384
            P
Sbjct: 843  P 843



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 150/736 (20%), Positives = 272/736 (36%), Gaps = 84/736 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII-KPKKNKYDFEKRG--HIR 1072
            P FI+K    +  +    I E +I ++    + W  + ++I    ++K+  +  G  +  
Sbjct: 118  PTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFA 177

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVV------ELP-------PEIITRLQNQKVN 1119
             L + N +  D G+Y    ++E   +  T+       E+P       P    R   ++ +
Sbjct: 178  TLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSD 237

Query: 1120 KGNKATFEIELTKGDA--LVRW--FKDGSEIQFSNHIQLTIDGKKQ-----KLKIYDCDL 1170
             G    FE     GD      W  + + +E+Q         +  +      +  I D   
Sbjct: 238  DGKNIVFECRCI-GDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQ 296

Query: 1171 DDAGEYSCEVGNSK--CTAILTVEEPS----INFTLRLPEFILVP--ANTDAYLTVEIPD 1222
             D G Y+    N     +AI+ +   S    +N   + P F   P  +     L++E   
Sbjct: 297  LDRGVYNVVAKNKHGDSSAIINLNFDSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECIL 356

Query: 1223 ETL---DVTWYKKKSVIEDTEKFTLI-----SDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
            E L   D+TW+     I D E+F ++     +D    TL I + T +D   Y C   +  
Sbjct: 357  EALPVADITWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPF 416

Query: 1273 ----AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
                A  T   K    +  F P  V+  +    K G+ +T+    ++ P+P  +W+   +
Sbjct: 417  GESNAHITLNFKANENDRGFAPSFVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQ 476

Query: 1327 IIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI---- 1377
             +K        +     D+   +L IK     D G Y   + N  G +   +N+ I    
Sbjct: 477  EVKSSNKVALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQ 536

Query: 1378 ---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---- 1430
                + P    KP+I+ +D+  + +  +    T     I +  E + I  T  + +    
Sbjct: 537  ESTKNAPIFVEKPHIVSLDNGKL-VRMECKVKTDLKPDITWTREGRIIQETTKLKITMTA 595

Query: 1431 -KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS--ETTEYYKVIKETKIQSPTVEKP 1487
             K++      +++ +T  S  ++    N +   +A+     E   VIKE       V+K 
Sbjct: 596  EKDVYHISLVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKR 655

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547
              +I        +  CI+          +R   K++  +   E                 
Sbjct: 656  TASIECAVASRFKPECIWMKETTVIKETHRHMIKIEETRQG-EFSVKLNITELSEADFGA 714

Query: 1548 YKCIAFNDHGEVETSCVVGIQ----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
            YK +A ND G+  TS V+ I+    +KP  T    D K K    DE     +  G+  P+
Sbjct: 715  YKLVAKNDKGQA-TSQVIEIKDIVFEKPPPTKPIIDPKLKDVEVDEGGNLTLAVGLVHPD 773

Query: 1604 ----VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
                V W KN   L+  +        + + + +K      +  Y +  SN   +   E  
Sbjct: 774  RHFKVYWMKNKTILKTSETVIQEFSGRMAKLTVKNCTVEDAGTYKVSISNEQQSDESEAK 833

Query: 1660 LKVYDKPSKPEGPVIM 1675
            +   ++  KPE P IM
Sbjct: 834  V---EEAKKPEVPKIM 846



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 3/129 (2%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           D  +Y+  +  +  E    L +  +   E    APIFVEK       +G  V+ EC+V+ 
Sbjct: 509 DGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKLVRMECKVKT 568

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYY---DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
             +P ITW R+  II+ +   ++      D    +LV+++   ED+GT+ C  KN  G  
Sbjct: 569 DLKPDITWTREGRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKCNIKNILGEL 628

Query: 593 SSTTELIVE 601
           ++   L +E
Sbjct: 629 NANLILNIE 637



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 81/407 (19%), Positives = 142/407 (34%), Gaps = 41/407 (10%)

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS----ASLTIKKVENTDAGIYKLRLENNCG 1367
            QA P+P   W  NSK+I      K  + +      A+L +  V   D+G YK+  +N  G
Sbjct: 142  QADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELG 201

Query: 1368 H--ADVEMNVTILDKPSPPG--KPNILEI-------DSSSINI---CWDEPENTGNSTII 1413
               A + +N    + P P    KP   E        D  +I     C  +P+ T    + 
Sbjct: 202  ESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVY 261

Query: 1414 YYVVEYQ---EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            +   E Q      +       +    + +I+++K      +   A N+   S A     +
Sbjct: 262  HEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQLDRGVYNVVAKNKHGDSSAIINLNF 321

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKT 1524
                K    +      P K   ++  E + + CI   +P   +TW+       DG++ K 
Sbjct: 322  DSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECILEALPVADITWFHGTETITDGERFKI 381

Query: 1525 AKATYENRX---XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
             +    N                   Y+C AFN  GE      +  +             
Sbjct: 382  LRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFGESNAHITLNFKANENDRGFAPSFV 441

Query: 1582 QKHKVGDEWLVTAV-----IEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKT--SVIR 1631
            +K K+    L T +         P P V W +   ++++  +  +   T  E T    + 
Sbjct: 442  EKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELTLN 501

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKPEGPVIMRE 1677
            IK+        Y+   SN  G SS  + L +  ++ S    P+ + +
Sbjct: 502  IKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEK 548


>UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein; n=1;
            Monodelphis domestica|Rep: PREDICTED: hypothetical
            protein - Monodelphis domestica
          Length = 3881

 Score =  186 bits (454), Expect = 4e-45
 Identities = 244/1098 (22%), Positives = 430/1098 (39%), Gaps = 114/1098 (10%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+ S          G + +LEC+   +P P + W   G E++    ++         + 
Sbjct: 609  PPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRGGLEMILAPEVA---------HT 659

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L+I  V++   G Y   AVN  G AS  I L++       P+++E  ++M+V  G + 
Sbjct: 660  GTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYA----PRLVESSRNMVVEMGRNA 715

Query: 753  ILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH---SITILKPKKVKDEGVYTLKAE 808
            IL+ +  G P P ITW + + KPV A P + +        +  L+    +D+ +Y  +A 
Sbjct: 716  ILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAH 775

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV-TRNPVPSITWY 867
            N+ G A+    +TV        EPP   +    + V E     L   V    P P   W 
Sbjct: 776  NTFGKAQAEVQLTV-----IGHEPPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWL 830

Query: 868  RNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            +  + + PS   +   DG  +I+  +     + D+G Y CV +N+ G  S    + + V+
Sbjct: 831  KEGQPL-PSSRYSIRTDGSFHIDRAL-----QEDAGRYSCVVTNTVG--SQRQDIELAVQ 882

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM----DHREIIQEGRXX 982
             +  +      Y T EG  + L C  S  + T     +KE + +     H ++++EG   
Sbjct: 883  VLPSILPTASHYVTNEGVPISLPC-VSRGIPTPTITWRKETNALSPRSSHHQVLKEG--- 938

Query: 983  XXXXXXXXXXDVGVIKCI------VKDQE------TSTMLVVKETIPEFIRKLQDFEVKE 1030
                      D G   C       +  QE      T   +++ E++ +  R +    +  
Sbjct: 939  SLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESL-DSDRPVTITALAG 997

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            K++ +      S +  + W +D +++ P  +++     G ++   +  TSV D G Y+CI
Sbjct: 998  KELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLK---LAETSVEDNGLYTCI 1054

Query: 1091 LRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSE 1145
              + + TA    V  V++PP+I    Q  KV  G         T GD    +RW KDG  
Sbjct: 1055 ASNPAGTASRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVAT-GDPKPQLRWSKDGIT 1113

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201
            +     +     G    + +    + D+G Y C    E G       L V EP   +   
Sbjct: 1114 LPQKGWV-----GPDGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEPP-RWEAE 1167

Query: 1202 LPEFILV-PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
              E +L   A  +A L   +         ++K    E       +S +   +L I   + 
Sbjct: 1168 DAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSS 1227

Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIK--RGSDVTLLVDYQAFPQP 1317
             D  +Y C   +   +   KV++V + PP     E+   +       +TL  D   FP P
Sbjct: 1228 QDSGDYECRATNEVGSVSRKVKLVVYVPPHFRGEEQRVNVSTLASRPLTLNCDVSGFPTP 1287

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               W  + + +   +  +      + SL   +V+ +D+ +Y  +  N  G A  + N+ +
Sbjct: 1288 AITWYKDGRPVS--EDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLV 1345

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
            L  PS  G     E+      +   E E     S +    VE+ +          +I   
Sbjct: 1346 LIPPSVRGAGTAQEVS----RLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLV 1401

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494
            +   Q LK  SS+   A     V  S A +  + +++  +T    PT+        +   
Sbjct: 1402 EDG-QVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQT---PPTIWGSNETGEVAVM 1457

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY-ENRXXXXXXXXXXXXXXXYKCIA 1552
             +  + L C   GVP P +TW +DG  L  + +  Y +                 Y C A
Sbjct: 1458 EDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYAKGGRHLQLGRARGSDSGLYTCQA 1517

Query: 1553 FNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             N  G  E +  + +   P I       +  K   G    +     G PPP + W+++ N
Sbjct: 1518 SNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDEN 1577

Query: 1612 KL-END--------------------KEY-NITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
             L EN+                    +E+  +      +++RI  ++  H+  +  +A+N
Sbjct: 1578 PLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATN 1637

Query: 1650 TAGTSSVEVTLKVYDKPS 1667
             AGT+  EV + V+++PS
Sbjct: 1638 EAGTAGAEVEVLVHEQPS 1655



 Score =  168 bits (409), Expect = 1e-39
 Identities = 275/1272 (21%), Positives = 461/1272 (36%), Gaps = 150/1272 (11%)

Query: 466  KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEK------LRPK 519
            K W   +YL    N      K  N  +   P+F+K     ++      E+      L  +
Sbjct: 2394 KAWDSGRYLCVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453

Query: 520  HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
               + +     C     P PQ+TW++     +P  D +          L I  V  EDAG
Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKDD---QPLSDIEGISVLQGGRVLQIPMVRSEDAG 2510

Query: 580  TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
             +TC A N  G      EL+V  P                        +++G P    ++
Sbjct: 2511 RYTCKASNEVGEDWLHYELLVLTP-----------------------PVIQGDPEELVEE 2547

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-----------ISVAIESDM 688
                 V+  S + L+C+ +  P P I+WL  G   +P              +SVA  +D 
Sbjct: 2548 VT---VNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQVLQVSVADAADS 2604

Query: 689  HMYCSV---------------------LKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
              Y  V                     L++   K    GTYT  A+N  G     ++L +
Sbjct: 2605 ASYMCVAENSAGSSEKLFTLKVQGTHTLQLPRPKPSDTGTYTCEALNVAGRDQKLVLLSV 2664

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDG 784
                           + +VR G++ +L  +    P P ITW KN + +   + + T  DG
Sbjct: 2665 FAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDG 2724

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
                I  ++   V D+G+Y+ K  N  G A  + V+ V+ P       P+F N  +E   
Sbjct: 2725 QKLEIVNVQ---VADKGLYSCKVSNIVGEAIRTFVLIVQVP-------PIFENPEKETLS 2774

Query: 845  KEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
            +  G  + LV  V   P P++TW ++   +  S        G  ++L       E   G 
Sbjct: 2775 QVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVSRGGRLQLSRLQPSQE---GT 2831

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST--KWY 961
            Y CVA N   ++     V + V        + + +   E + V LEC+          W 
Sbjct: 2832 YTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWL 2891

Query: 962  HNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIP 1017
             + + +      H     +G             D G   C+ ++   E + +  V   +P
Sbjct: 2892 KDGRPLGVHTAPHLRFYTDG--SSLVLKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVP 2949

Query: 1018 EFIRKLQD-----FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
              I +  +       V+ + V +      S    + W +DG +  P   +      G  R
Sbjct: 2950 PTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKDG-LPMPLSQRTHLHSSG--R 3006

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPP--EIITRLQNQKVNKGNKATFE 1127
             L I    V D G ++C+    +  AE T    + +PP  E         V +G+  T  
Sbjct: 3007 TLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLEPSETKDAMAVVRGSDVTLP 3066

Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
             E  +G  L  V W KDG+ +      +L + G    L++     DD G YSC   N   
Sbjct: 3067 CE-ARGSPLPAVSWLKDGASLMLQ---RLGL-GSGSSLQLEAVQADDVGTYSCVAINEAG 3121

Query: 1186 TA-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
             A     +  +E P I  + +  E +L+P      +   +     ++TW K   V+    
Sbjct: 3122 EATRHFQLAVMEPPHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLARLG 3181

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRI 1299
              T       R L +     DD   YTC+  + A    K  +  V+ PP IV   RE R 
Sbjct: 3182 SITKDG----RVLRVEGVQVDDAGLYTCLAENPAGEDGKNFLVRVQAPPNIVG-SRETRT 3236

Query: 1300 KRG-SDVTLLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
              G +D  L+++   +A P P  EW     +++   HT          L ++ ++ +D+G
Sbjct: 3237 VIGLADGQLVLECPVEADPPPKIEWHREGVLLQADAHTL--FLENGRFLQLQALDTSDSG 3294

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             Y     N  G   +  +V I   P+    P+++ +  +   +   +      S + +  
Sbjct: 3295 DYNCVASNAAGSTSLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRK 3354

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
                 +  +  +    ++     IQ +    S  +   A N    SD           +E
Sbjct: 3355 DGIPLVPGSPRLEF--LSDGSLRIQPVYPQDSGYYLCQASNSAG-SDRQG--------RE 3403

Query: 1477 TKI-QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535
             ++ + PT+     N+T   +    L C   G P+P V W ++G+ L   +     R   
Sbjct: 3404 LRVFEPPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQTLSLDRHQEAYRLLP 3463

Query: 1536 XXXXXXX----XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            ++C+  ND GE      V +   P I     D           +
Sbjct: 3464 SSSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYVPPTIADDRTDFTVTKMA--PVV 3521

Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            +T    G+P P V W K G +L +    Y ++    T  + I++    H+ +YT  A N 
Sbjct: 3522 LTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVS---PTGALEIEQALPIHTGRYTCTARNA 3578

Query: 1651 AGTSSVEVTLKV 1662
            AG +   V L V
Sbjct: 3579 AGVAHKHVILMV 3590



 Score =  144 bits (348), Expect = 3e-32
 Identities = 258/1218 (21%), Positives = 444/1218 (36%), Gaps = 136/1218 (11%)

Query: 523  DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            +G      C V  G P PQ  W ++   + PS  + +  D     +  I     EDAG +
Sbjct: 808  EGQPASLPCVVLAGKPFPQRHWLKEGQPL-PSSRYSIRTD----GSFHIDRALQEDAGRY 862

Query: 582  TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
            +CV  N  G      EL V+                          +L  I PT S    
Sbjct: 863  SCVVTNTVGSQRQDIELAVQ--------------------------VLPSILPTAS---- 892

Query: 642  AQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
              YV +EG  I L C    IP P I W  +   + P  +    ++         L +   
Sbjct: 893  -HYVTNEGVPISLPCVSRGIPTPTITWRKETNALSPRSSHHQVLKEGS------LYLPQP 945

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGEK----EPPQVIEPLKSMIVRQGESVILSA 756
                 GTY   A N  G +S  I L + T  +    E      P+ ++    G+ + L  
Sbjct: 946  SAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDSDRPV-TITALAGKELTLHC 1004

Query: 757  QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            +  G+P P ITW K+++ +  +  +          L    V+D G+YT  A N  G A  
Sbjct: 1005 EAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASR 1064

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            S V+ V+ P +    P L       + V    ++ L    T +P P + W ++   +   
Sbjct: 1065 SYVLGVQVPPQIQQGPQL-------LKVLAGESLDLTCVATGDPKPQLRWSKDGITLPQK 1117

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
              +    DG ++ L    V    DSG Y CVAS+ AG+ +    + +        +  + 
Sbjct: 1118 GWVGP--DG-SVHLESVQVS---DSGHYHCVASSEAGEDARELELEVLEPPRWEAEDAEA 1171

Query: 937  SYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-DHREIIQEGRXXXXXXXXXXXXDVG 995
              E   G+   L C  + T + +    K     +   +  +                D G
Sbjct: 1172 LLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSG 1231

Query: 996  VIKCIVKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSE-----TADVV 1048
              +C   ++  S    VK  +  P   R  ++  V    +A   + +N +     T  + 
Sbjct: 1232 DYECRATNEVGSVSRKVKLVVYVPPHFRG-EEQRVNVSTLASRPLTLNCDVSGFPTPAIT 1290

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVEL 1105
            W +DG  +  + N++ F        L+       D   Y+C   + +  A+     +V +
Sbjct: 1291 WYKDGRPVS-EDNRHYFPDGAP--SLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLVLI 1347

Query: 1106 PPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDGSEIQFSN-HIQLTIDGKKQ 1161
            PP +      Q+V++      E+E  T G  L  V W KDG  +   + HIQL  DG  Q
Sbjct: 1348 PPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDG--Q 1405

Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
             LKI    L DAG Y C      G       L+++ P   +       + V  +    L 
Sbjct: 1406 VLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQ 1465

Query: 1218 VEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
             +     T  +TW K    +  + +         R L + +    D   YTC   +A   
Sbjct: 1466 CDARGVPTPAITWLKDGDPLHASPRVAYAKG--GRHLQLGRARGSDSGLYTCQASNAAGI 1523

Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFPQP--------------N 1318
             +  V + V  PP I   +    + +   G  + L       P P              N
Sbjct: 1524 AEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENPLTENN 1583

Query: 1319 DEWI-VNSKIIKKCKHTKPS-------IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
              W+    ++++  ++ +P+       + +  A L I  V+    G++  +  N  G A 
Sbjct: 1584 GTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAG 1643

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
             E+ V + ++PS      +  ++  +I   + +P      TI          + + W + 
Sbjct: 1644 AEVEVLVHEQPS------VTVLEGENITAPFLQP-----VTIQCVAAGMPVPNLSWWKNG 1692

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
             ++  T  S+Q  K +       Y     +++  ++     KV     +  P +E  L N
Sbjct: 1693 VSLVTTGGSLQIEKVDLRDEGN-YTCVATNLAGEAKRDVVLKV-----LVPPNIEPGLVN 1746

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXY 1548
                 N    L C+  GVP P+++WYR  + +  K       +                Y
Sbjct: 1747 KAVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSY 1806

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            +C+A N  G  E    + I   P IT++   +     + +   +     G P P ++W K
Sbjct: 1807 RCVASNVAGSSELKFGLRINVPPRITLA-PSLPGPVLLNEPVRLVCNATGAPTPMLMWLK 1865

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            +GN +       +       V+ +   + + +  YT  A N  G    +VTL+V+  PS 
Sbjct: 1866 DGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSI 1925

Query: 1669 PEGPVIMREISRESVTIE 1686
                  +  +  +SVT+E
Sbjct: 1926 LGEEQNVSVVVNQSVTLE 1943



 Score =  143 bits (347), Expect = 4e-32
 Identities = 271/1266 (21%), Positives = 459/1266 (36%), Gaps = 150/1266 (11%)

Query: 475  MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534
            + E +   Y+ K +NE    L         E   AP  VE  R      G      C+ E
Sbjct: 667  VQERDAGNYICKAVNE----LGAASADIRLEVGYAPRLVESSRNMVVEMGRNAILACRAE 722

Query: 535  GYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
            G P P+ITW R      P+   +           L +  V PED   + C A N  G A 
Sbjct: 723  GRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAHNTFGKAQ 782

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653
            +  +L V       G E                 +LEG P +                 L
Sbjct: 783  AEVQLTV------IGHEPP-----QIASSASMVRVLEGQPAS-----------------L 814

Query: 654  ECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
             C ++A  P P   WL +G+ + P    S+  +   H       I    +   G Y+ V 
Sbjct: 815  PCVVLAGKPFPQRHWLKEGQPL-PSSRYSIRTDGSFH-------IDRALQEDAGRYSCVV 866

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             N  G     I L ++      P ++      +  +G  + L     G P PTITW K  
Sbjct: 867  TNTVGSQRQDIELAVQV----LPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKET 922

Query: 773  KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
              +    +           L     +D G Y   A N+ GI+     ++V          
Sbjct: 923  NALSPRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNE 982

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
             L  +R   IT      + L      +P P ITW ++++++SP           +++L  
Sbjct: 983  SLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAE 1042

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
            T+V+   D+G Y C+ASN AG +S      + V+    ++   +  +   G+++ L C  
Sbjct: 1043 TSVE---DNGLYTCIASNPAGTASRS--YVLGVQVPPQIQQGPQLLKVLAGESLDLTCVA 1097

Query: 953  SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012
            +     +   +K  I+ +  +  +  G             D G   C+   +       +
Sbjct: 1098 TGDPKPQLRWSKDGIT-LPQKGWV--GPDGSVHLESVQVSDSGHYHCVASSEAGEDAREL 1154

Query: 1013 KETIPEFIR-KLQDFEVKEKDVAILEVEI-----NSETADVVWERD--GEIIKPKKNKYD 1064
            +  + E  R + +D E   + VA     +      + T  V+W +D   E++  +     
Sbjct: 1155 ELEVLEPPRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSV 1214

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEV-TVVELPPEIITRLQNQKVNKG 1121
                     L+I + S  D G+Y C   +E  S + +V  VV +PP    R + Q+VN  
Sbjct: 1215 LND----SSLFIASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPPHF--RGEEQRVNVS 1268

Query: 1122 NKATFEIEL---TKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
              A+  + L     G     + W+KDG  +   N      DG    L        D+  Y
Sbjct: 1269 TLASRPLTLNCDVSGFPTPAITWYKDGRPVSEDNRHYFP-DG-APSLHFPQVQKSDSDLY 1326

Query: 1177 SCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWY 1230
            +C+  N      K   +L +  PS+       E   + A  +  L        L  V W 
Sbjct: 1327 TCQAVNPAGMAQKDFNLLVLIPPSVRGAGTAQEVSRL-AGLEVELECRTSGVPLPQVEWT 1385

Query: 1231 KK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288
            K  + V        L+ D   + L I      D   Y CV            ++ ++ PP
Sbjct: 1386 KDGQPVAPGDPHIQLVED--GQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPP 1443

Query: 1289 KI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-- 1344
             I   +   E  +     V L  D +  P P   W+ +   +    H  P +        
Sbjct: 1444 TIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKDGDPL----HASPRVAYAKGGRH 1499

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHA------DVEMNVTILDKPSPP-------GKPNILE 1391
            L + +   +D+G+Y  +  N  G A      DV +  TI      P       G+P  L 
Sbjct: 1500 LQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALG 1559

Query: 1392 IDSSS---INICWDEPEN---TGNSTIIY---YVVEY--QEIDTTEWISVKNITK-TQTS 1439
              +S      + W + EN     N T +     V+ +        E+  V+  T      
Sbjct: 1560 CSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLR 1619

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I +++ + +  F   A NE   + A      ++    T ++        +NIT    + +
Sbjct: 1620 IDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEG-------ENITAPFLQPV 1672

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             + C+  G+P P ++W+++G  L T   + +                 Y C+A N  GE 
Sbjct: 1673 TIQCVAAGMPVPNLSWWKNGVSLVTTGGSLQ------IEKVDLRDEGNYTCVATNLAGEA 1726

Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            +   V+ +   P I   + N+ + +      E L +    G+P P + WY+    + +  
Sbjct: 1727 KRDVVLKVLVPPNIEPGLVNKAVLENTSASLECLAS----GVPTPRISWYRGRQPISSKP 1782

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEG 1671
               +++  +  V+RIK  + S +  Y   ASN AG+S ++  L++         PS P G
Sbjct: 1783 GLMVSSDGR--VLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLP-G 1839

Query: 1672 PVIMRE 1677
            PV++ E
Sbjct: 1840 PVLLNE 1845



 Score =  136 bits (329), Expect = 6e-30
 Identities = 255/1257 (20%), Positives = 454/1257 (36%), Gaps = 116/1257 (9%)

Query: 476  DENNYTQYLQKKLNEKIDK--LPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
            D   YT  +  ++ E +    + V   P+ S++  +    V++++ K     ST+  EC+
Sbjct: 2299 DAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVN---STLSLECE 2355

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
                P P ITW++   ++ P     +  D      L I      D+G + CVA N AG  
Sbjct: 2356 SWAMPPPTITWYKDGQLVSPDNRLHLLADG---RLLQINPTKAWDSGRYLCVATNVAGED 2412

Query: 593  SSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
                 ++V+  P+     +                 +LE            + + E +  
Sbjct: 2413 DKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLE-----------YREIVENNPA 2461

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
             L C   A+P P + W +K ++ + D E ISV           VL+I  V+    G YT 
Sbjct: 2462 YLYCDTNAVPPPQLTW-YKDDQPLSDIEGISVLQGG------RVLQIPMVRSEDAGRYTC 2514

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
             A N  GE  L   L + T         E ++ + V    +V L  Q +G P P I+W +
Sbjct: 2515 KASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLR 2574

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE------TSAVITVEE 824
            N  P          +   +  +      D   Y   AENS G +E           T++ 
Sbjct: 2575 NGLPFIPSSKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEKLFTLKVQGTHTLQL 2634

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P  + ++   +      +  +++  + L          +    R+  ++   +T   + +
Sbjct: 2635 PRPKPSDTGTYTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCE 2694

Query: 885  GENI-ELVIT------------NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--T 929
             + + E VIT             V + +D    + V    A K  +  +V+  V +   T
Sbjct: 2695 SDTLPEPVITWYKNGQQIALDQQVQTLLDGQKLEIVNVQVADKGLYSCKVSNIVGEAIRT 2754

Query: 930  FVKHLQ--KSYETEE--------GKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977
            FV  +Q    +E  E        G  ++L C  +     +  W  ++  +     R ++ 
Sbjct: 2755 FVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVS 2814

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRK--LQDFEVKEKD 1032
             G               G   C+ ++ E       +V+    P  +     Q+  + E+ 
Sbjct: 2815 RG--GRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQ 2872

Query: 1033 VAILEVEINSE-TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
               LE E   +   D+ W +DG  +      +  F   G    L ++     D G Y+C+
Sbjct: 2873 EVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDG--SSLVLKGLKSSDSGAYTCL 2930

Query: 1091 LRDE--SCTAEVTVVELPPEIITRLQNQKVN----KGNKATFEIELTKGDAL-VRWFKDG 1143
             ++     T   TV  L P  I R  N   N    +G   T          + + W KDG
Sbjct: 2931 AQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKDG 2990

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFT 1199
              +  S    L   G+   L+I    + DAG ++C      G ++ T  L +  P +   
Sbjct: 2991 LPMPLSQRTHLHSSGR--TLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLEP 3048

Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
                + + V   +D  L  E     L  V+W K  + +   ++  L S     +L +   
Sbjct: 3049 SETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKDGASLM-LQRLGLGSG---SSLQLEAV 3104

Query: 1259 TEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAF 1314
              DD   Y+CV ++   ++T   ++ V+E PP I D     E  +  G+ + L+ +    
Sbjct: 3105 QADDVGTYSCVAINEAGEATRHFQLAVME-PPHIEDSGQAEEMLLLPGAPLELICNALGS 3163

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P PN  W  + +++ +      SI      L ++ V+  DAG+Y    EN  G       
Sbjct: 3164 PMPNITWQKDGQVLARL----GSITKDGRVLRVEGVQVDDAGLYTCLAENPAGEDGKNFL 3219

Query: 1375 VTILDKPSPPG-KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT-TEWISVKN 1432
            V +   P+  G +     I  +   +  + P        I +  E   +      + ++N
Sbjct: 3220 VRVQAPPNIVGSRETRTVIGLADGQLVLECPVEADPPPKIEWHREGVLLQADAHTLFLEN 3279

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
                Q  +Q L T+ S  +   A N    +    + E +         +PT++     + 
Sbjct: 3280 GRFLQ--LQALDTSDSGDYNCVASNAAGSTSLPFSVEIH--------MAPTIQPGPSVVN 3329

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKC 1550
               NE   L C   G+P   V+W +DG  L       E  +                Y C
Sbjct: 3330 VSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGSPRLEFLSDGSLRIQPVYPQDSGYYLC 3389

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             A N  G       + + + P I     ++     V  +  +     G P P V+W KNG
Sbjct: 3390 QASNSAGSDRQGRELRVFEPPTIAPGPSNLTL--TVHTQATLPCEARGSPKPHVVWKKNG 3447

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
              L  D+         +S + + +     ++++    SN AG +     + VY  P+
Sbjct: 3448 QTLSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYVPPT 3504



 Score =  117 bits (282), Expect = 3e-24
 Identities = 176/801 (21%), Positives = 303/801 (37%), Gaps = 88/801 (10%)

Query: 633  PPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            PPT   S +     V E   + L+C    +P P I WL  G+ +     ++ A +   H 
Sbjct: 1442 PPTIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYA-KGGRH- 1499

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                L++   +    G YT  A N  G A   + L +            PL    V  G 
Sbjct: 1500 ----LQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVA-GR 1554

Query: 751  SVILSAQVVGNPRPTITW------------------------CKNNKPVK---ALPTKSD 783
             + L     G+P PT+TW                         +N +P +    +   +D
Sbjct: 1555 PLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTD 1614

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
            G    I  ++P      G++  +A N  G A     + V E      +P + +   + IT
Sbjct: 1615 GAMLRIDHVQPDH---NGLFACQATNEAGTAGAEVEVLVHE------QPSVTVLEGENIT 1665

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
                  + +       PVP+++W++N   +S   T      G +++  I  VD   D G+
Sbjct: 1666 APFLQPVTIQCVAAGMPVPNLSWWKNG--VSLVTT------GGSLQ--IEKVDLR-DEGN 1714

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWY 961
            Y CVA+N AG++     + + V        + K+    E  +  LEC  S   T    WY
Sbjct: 1715 YTCVATNLAGEAKRDVVLKVLVPPNIEPGLVNKA--VLENTSASLECLASGVPTPRISWY 1772

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV--VKETIPEF 1019
              ++ IS      +  +GR            D G  +C+  +   S+ L   ++  +P  
Sbjct: 1773 RGRQPISSKPGLMVSSDGRVLRIKRAQLS--DAGSYRCVASNVAGSSELKFGLRINVPPR 1830

Query: 1020 IR---KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK-YDFEKRGHIRKLY 1075
            I     L    +  + V ++     + T  ++W +DG  +             GH+  L 
Sbjct: 1831 ITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHV--LT 1888

Query: 1076 IRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTK 1132
            +  +   D G Y+C+  +       +VT+ V LPP I+   QN  V      T E +   
Sbjct: 1889 LAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLECQSQA 1948

Query: 1133 -GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
                ++ W KDG  +     + L+ DG    L++   ++ D G Y+CE     G S+   
Sbjct: 1949 VPPPVLSWRKDGHALSPRPGVHLSADGVL--LQVERAEVQDVGRYTCEALNKAGRSEKHY 2006

Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLIS 1246
             L V  P   F+   P  + V       L+ E        +TW K   ++      T   
Sbjct: 2007 NLNVWVPP-EFSFWEPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPI 2065

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRG 1302
                R L + K     +  YTC    +   S+ +  +EV   P  P   D+ +E  +   
Sbjct: 2066 SAVGRLLYLGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHS 2125

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
             +VTL  +    P P   W  + +++ + +     +  +  +L +++     AG Y    
Sbjct: 2126 GEVTLECEATGKPPPVVTWEKDGQLVTRDQGLL--LQHRGRALQVEQARAAHAGRYTCIA 2183

Query: 1363 ENNCGHADVEMNVTILDKPSP 1383
            EN  G A+   ++++L  PSP
Sbjct: 2184 ENEAGRAEQRFDLSVLGNPSP 2204



 Score =  116 bits (279), Expect = 7e-24
 Identities = 178/806 (22%), Positives = 300/806 (37%), Gaps = 67/806 (8%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            V+ +C   G P P ITW +    +  S   ++ Y       L +      D+G +TC A 
Sbjct: 1462 VRLQCDARGVPTPAITWLKDGDPLHASP--RVAYAKGG-RHLQLGRARGSDSGLYTCQAS 1518

Query: 587  NAAGFASSTTELIVEAPLSDHGSE--MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            NAAG A     L V  P +  G++    V                   PPT +       
Sbjct: 1519 NAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENP 1578

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            + E +   L+          + WL  G     +E   V + +D  M    L+I +V+   
Sbjct: 1579 LTENNGTWLQ-----EGGRVLRWLRNGRPA--EEFAGVEVSTDGAM----LRIDHVQPDH 1627

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G +   A N  G A   + + +    ++P   +   +++     + V +     G P P
Sbjct: 1628 NGLFACQATNEAGTAGAEVEVLV---HEQPSVTVLEGENITAPFLQPVTIQCVAAGMPVP 1684

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             ++W KN   V  + T       S+ I K   ++DEG YT  A N  G A+   V+ V  
Sbjct: 1685 NLSWWKNG--VSLVTTGG-----SLQIEK-VDLRDEGNYTCVATNLAGEAKRDVVLKVLV 1736

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P   N EP L +N+     V E  +  L    +  P P I+WYR  + IS    +  + D
Sbjct: 1737 P--PNIEPGL-VNK----AVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSSD 1789

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKS--SHGARVTIDVEKVTFVKHLQKSYETEE 942
            G  + +    +    D+G Y+CVASN AG S    G R+ +   ++T    L       E
Sbjct: 1790 GRVLRIKRAQLS---DAGSYRCVASNVAGSSELKFGLRINVP-PRITLAPSLPGPVLLNE 1845

Query: 943  GKTVILECQTSHTVSTKWYHNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
               ++     + T    W  +   +S  G    +I   G             D G   C+
Sbjct: 1846 PVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGH--VLTLAGSRATDAGTYTCV 1903

Query: 1001 VKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII 1056
              +   ++   + +     P  + + Q+  V       LE +  +    V+ W +DG  +
Sbjct: 1904 AVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLECQSQAVPPPVLSWRKDGHAL 1963

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI-ITR 1112
             P+   +     G +  L +    V D G Y+C   +++  +E      V +PPE     
Sbjct: 1964 SPRPGVH-LSADGVL--LQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWVPPEFSFWE 2020

Query: 1113 LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             +   V +G+  +   E        + W KDG  +         I    + L +      
Sbjct: 2021 PRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLYLGKAQPS 2080

Query: 1172 DAGEYSCE----VGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
              G Y+CE     GNS     L V   P +  +    + + V  + +  L  E   +   
Sbjct: 2081 QEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGEVTLECEATGKPPP 2140

Query: 1227 -VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283
             VTW K   ++  T    L+   + R L + +        YTC+  +   ++  +  + V
Sbjct: 2141 VVTWEKDGQLV--TRDQGLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAEQRFDLSV 2198

Query: 1284 VEFPPKIVDYER-EYRIKRGSDVTLL 1308
            +  P  ++ + R E  I  G DV  L
Sbjct: 2199 LGNPSPLIRWFRGEEPISPGEDVYFL 2224



 Score =  114 bits (274), Expect = 3e-23
 Identities = 209/1071 (19%), Positives = 400/1071 (37%), Gaps = 90/1071 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP     P+   V  G   LL C+++     ++ W+ +   ++P     V   +++    
Sbjct: 428  PPPQLASPQNVTVSPGETALLSCQVLDKAPYNLTWV-RDWRVLPASPGRVVQLANLS--- 483

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L+I+ +     G Y  +A N  G     + L I+    EPPQ+     S    QG  +
Sbjct: 484  --LEISGIIPSDGGKYQCLASNANGITRASVWLLIR----EPPQISINTSSRHFSQGVEL 537

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             +S    G P P I+W  N++ +  +  +   D     I++    +D G Y+ +A N  G
Sbjct: 538  RISCTASGYPPPHISWRHNDQTI-GMDGRFLVDDQGTLIIQSVTPEDAGNYSCQATNEVG 596

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN--N 870
              E +  +   EP   +A  P+ +    E  V E        + +  P P + WYR    
Sbjct: 597  TDEQTVTLFYTEPPSVSALRPVVLAPIGEEAVLE-------CKASGVPPPRVIWYRGGLE 649

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
             I++P    T     + ++        E D+G+Y C A N  G +S  A + ++V     
Sbjct: 650  MILAPEVAHTGTLRIQEVQ--------ERDAGNYICKAVNELGAAS--ADIRLEVGYAPR 699

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVSTK--W--YHNKKEISGMDHREIIQEGRXXXXXX 986
            +    ++   E G+  IL C+     S +  W     K   +        ++        
Sbjct: 700  LVESSRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFL 759

Query: 987  XXXXXXDVGVIKC-----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE--VE 1039
                  D  +  C       K Q    + V+    P+         V E   A L   V 
Sbjct: 760  ENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQPASLPCVVL 819

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
                     W ++G+ +    ++Y     G     +I      D G YSC++ +   +  
Sbjct: 820  AGKPFPQRHWLKEGQPL--PSSRYSIRTDG---SFHIDRALQEDAGRYSCVVTNTVGSQR 874

Query: 1100 VTV---VELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ-FSNHIQ 1153
              +   V++ P I+    +   N+G   +    +++G     + W K+ + +   S+H Q
Sbjct: 875  QDIELAVQVLPSILPTASHYVTNEGVPISLPC-VSRGIPTPTITWRKETNALSPRSSHHQ 933

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSI--NFTLRLPEFI 1206
            +  +G    L +      D+G Y C   N+   +   ++     +P I  N +L     +
Sbjct: 934  VLKEG---SLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDSDRPV 990

Query: 1207 LVPANTDAYLTVEIPDETLD---VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDD 1262
             + A     LT+    E      +TW K   ++   T++ +L+      +L + + + +D
Sbjct: 991  TITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLL---PSGSLKLAETSVED 1047

Query: 1263 QCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
               YTC+  + A + ++  V  V+ PP+I    +  ++  G  + L       P+P   W
Sbjct: 1048 NGLYTCIASNPAGTASRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVATGDPKPQLRW 1107

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              +   + +     P       S+ ++ V+ +D+G Y     +  G    E+ + +L+ P
Sbjct: 1108 SKDGITLPQKGWVGP-----DGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEPP 1162

Query: 1382 --SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQT 1438
                     +LE  +            T    +I+      E+ +++  +SV N   +  
Sbjct: 1163 RWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLN--DSSL 1220

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             I ++ +  S  +   A NEV        +   K++          E+ + N++T  +  
Sbjct: 1221 FIASVSSQDSGDYECRATNEV-----GSVSRKVKLVVYVPPHFRGEEQRV-NVSTLASRP 1274

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            + L C   G P P +TWY+DG+ +      Y  +                 Y C A N  
Sbjct: 1275 LTLNCDVSGFPTPAITWYKDGRPVSEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPA 1334

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G  +    + +   P +  +    +     G E  +     G+P P+V W K+G  +   
Sbjct: 1335 GMAQKDFNLLVLIPPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVA-P 1393

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             + +I   E   V++I       +  Y   A + AG  + +  L +   P+
Sbjct: 1394 GDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPT 1444



 Score =  105 bits (252), Expect = 1e-20
 Identities = 141/686 (20%), Positives = 273/686 (39%), Gaps = 52/686 (7%)

Query: 1028 VKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
            V+  D A+L  E ++    V+ W ++G+ I   +           +KL I N  V D+G 
Sbjct: 2683 VRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDG---QKLEIVNVQVADKGL 2739

Query: 1087 YSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNK--GNKATFEIELTKGDA-LVRWF 1140
            YSC + +   E+    V +V++PP I    + + +++  GN      ++    A  V W 
Sbjct: 2740 YSCKVSNIVGEAIRTFVLIVQVPP-IFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWL 2798

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPS 1195
            KD   ++ S  ++  +  +  +L++        G Y+C   N +  A     ++ +  P 
Sbjct: 2799 KDRMPVESS--VERGVVSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPR 2856

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
            I  +  +P+   +    +  L  E   +   D++W K    +       L       +L+
Sbjct: 2857 I-LSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSSLV 2915

Query: 1255 IRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVD 1310
            ++     D   YTC+  ++    TKL    V  PP I    +        +G  VT+   
Sbjct: 2916 LKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACP 2975

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
             +  P     W+ +   +   + T   + S   +L I +V+  DAG +     +  G A+
Sbjct: 2976 ARGSPPIQINWLKDGLPMPLSQRTH--LHSSGRTLRISQVQVADAGTFTCVASSPAGVAE 3033

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
               ++ I         P +LE   +   +        G+   +        +    W+  
Sbjct: 3034 RTFSLQI-------HVPPVLEPSETKDAMAVVR----GSDVTLPCEARGSPLPAVSWL-- 3080

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVD------ISDASETTEYYKVIKETKIQSPTV 1484
            K+          L + SS +  A   ++V       I++A E T ++++     ++ P +
Sbjct: 3081 KDGASLMLQRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQL---AVMEPPHI 3137

Query: 1485 EKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
            E     + +   P   +EL C   G P P +TW +DG+ L    +  ++           
Sbjct: 3138 EDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLARLGSITKDGRVLRVEGVQV 3197

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
                 Y C+A N  GE   + +V +Q  P I  S E          + ++   +E  PPP
Sbjct: 3198 DDAGLYTCLAENPAGEDGKNFLVRVQAPPNIVGSRETRTVIGLADGQLVLECPVEADPPP 3257

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++ W++ G  L+ D   +    E    ++++ L  S S  Y   ASN AG++S+  ++++
Sbjct: 3258 KIEWHREGVLLQADA--HTLFLENGRFLQLQALDTSDSGDYNCVASNAAGSTSLPFSVEI 3315

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWK 1688
            +  P+   GP ++     E+  +  K
Sbjct: 3316 HMAPTIQPGPSVVNVSVNETALLPCK 3341



 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 186/936 (19%), Positives = 350/936 (37%), Gaps = 85/936 (9%)

Query: 771  NNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYT-LKAENSEGIAETSAVITVEEPTE 827
            + +P+  LP  S  +T  H + +  P +V  E  Y  +K E+ EG      V  V     
Sbjct: 366  SGQPLLTLPAGSLSNTSSHQLWVGPPFRVPKERFYLKVKGEDHEG-NPLHRVSNVAYNGV 424

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDG 885
                PP   +  Q +TV    T  L  +V      ++TW R+  ++  SP   +      
Sbjct: 425  APDPPPQLASP-QNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQL---- 479

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
             N+ L I+ +    D G Y+C+ASN+ G +   A V + + +   +     S    +G  
Sbjct: 480  ANLSLEISGIIPS-DGGKYQCLASNANGITR--ASVWLLIREPPQISINTSSRHFSQGVE 536

Query: 946  VILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC---- 999
            + + C  S        W HN + I GMD R ++ +              D G   C    
Sbjct: 537  LRISCTASGYPPPHISWRHNDQTI-GMDGRFLVDD--QGTLIIQSVTPEDAGNYSCQATN 593

Query: 1000 -IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG--EI 1055
             +  D++T T+   +      +R +    + E+  A+LE + +      V+W R G   I
Sbjct: 594  EVGTDEQTVTLFYTEPPSVSALRPVVLAPIGEE--AVLECKASGVPPPRVIWYRGGLEMI 651

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITR 1112
            + P+          H   L I+     D G Y C   +E  + +A++ + V   P ++  
Sbjct: 652  LAPEV--------AHTGTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYAPRLVES 703

Query: 1113 LQNQKVNKGNKATFEIELT-KGDALVRWFK-DGSEIQFSNHIQLTIDGKKQK------LK 1164
             +N  V  G  A        +    + W + DG  +         ++G + +      L 
Sbjct: 704  SRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAH-----PVEGNRARQLEAGVLF 758

Query: 1165 IYDCDLDDAGEYSCEV----GNSKCTAILTV---EEPSINFTLRLPEFIL-VPANTDAYL 1216
            + +   +D   Y CE     G ++    LTV   E P I  +  +   +   PA+    +
Sbjct: 759  LENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQPASLPCVV 818

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
                P       W K+   +  + ++++ +D    +  I +  ++D   Y+CV+ +   +
Sbjct: 819  LAGKPFPQRH--WLKEGQPL-PSSRYSIRTD---GSFHIDRALQEDAGRYSCVVTNTVGS 872

Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHT 1334
             +  +E+ V+  P I+     Y    G  ++L    +  P P   W   +  +  +  H 
Sbjct: 873  QRQDIELAVQVLPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKETNALSPRSSHH 932

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            +     K  SL + +    D+G Y     N  G +  E+ +++        KP I+  +S
Sbjct: 933  QV---LKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSV------NTKPRIIMNES 983

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
               +         G    ++   E        W     +    T   +L  + S +    
Sbjct: 984  LDSDRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAET 1043

Query: 1455 AVNE----VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +V +      I+     T     +   ++  P +++  + +     E ++LTC+  G P+
Sbjct: 1044 SVEDNGLYTCIASNPAGTASRSYVLGVQV-PPQIQQGPQLLKVLAGESLDLTCVATGDPK 1102

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            P++ W +DG  L   K                     Y C+A ++ GE      + + + 
Sbjct: 1103 PQLRWSKDGITL-PQKGWVGPDGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEP 1161

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P     + +   +   G+   +   + G P P VIW K+        +  ++    +S+ 
Sbjct: 1162 PRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLF 1221

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             I  +    S  Y   A+N  G+ S +V L VY  P
Sbjct: 1222 -IASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPP 1256



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 112/440 (25%), Positives = 168/440 (38%), Gaps = 66/440 (15%)

Query: 528  QFECQVEGYPRPQITWFRQTAIIKPSQDFQ-------------------MYYDDDNVATL 568
            +F+  V G P P I WFR    I P +D                     +Y    N + L
Sbjct: 2193 RFDLSVLGNPSPLIRWFRGEEPISPGEDVYFLAGGRILKLTRVQEEEGGLYMCLANGSLL 2252

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTEL---------IVEAPLSDHGS-EMTVXXXXX 618
             I +     +G ++C+A N+    +   +L         I+ A   D G     V     
Sbjct: 2253 EILQANFSSSGHYSCIASNSVSEKTKHYKLSVLGTHGLQILNAQEQDAGRYTCVVTNEVG 2312

Query: 619  XXXXXXXADILEGIPPTFSKK-PKAQY-VDE-----GSDILLECRLVAIPEPDIAWLFKG 671
                    ++L  IPP+ SK  P  ++ V E      S + LEC   A+P P I W   G
Sbjct: 2313 EAVKNYHVEVL--IPPSISKDDPLDEFSVKEVKAKVNSTLSLECESWAMPPPTITWYKDG 2370

Query: 672  EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL---------P 722
            + + PD  + +  +        +L+I   K +  G Y  VA N  GE            P
Sbjct: 2371 QLVSPDNRLHLLADG------RLLQINPTKAWDSGRYLCVATNVAGEDDKDFNVLVQVPP 2424

Query: 723  IVLKIKTGEK--EPPQVIEPLKSMIVRQGESV-----ILSAQVVGNPRPTITWCKNNKPV 775
            I  KI    +  E     E L+  ++   E V      L       P P +TW K+++P+
Sbjct: 2425 IFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDTNAVPPPQLTWYKDDQPL 2484

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
              +   S      +  +   + +D G YT KA N  G       + V  P     +P   
Sbjct: 2485 SDIEGISVLQGGRVLQIPMVRSEDAGRYTCKASNEVGEDWLHYELLVLTPPVIQGDPEEL 2544

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
            +   +E+TV    T+ L  +    P P I+W RN     PS       DG+ +++   +V
Sbjct: 2545 V---EEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQVLQV---SV 2598

Query: 896  DSEIDSGDYKCVASNSAGKS 915
                DS  Y CVA NSAG S
Sbjct: 2599 ADAADSASYMCVAENSAGSS 2618



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 125/590 (21%), Positives = 219/590 (37%), Gaps = 50/590 (8%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            PP  +T  Q++     N  T+   L +G  ++RW ++G   +    ++++ DG    L+I
Sbjct: 1566 PPPTLTWHQDENPLTENNGTW---LQEGGRVLRWLRNGRPAEEFAGVEVSTDGAM--LRI 1620

Query: 1166 YDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYLT-VE 1219
                 D  G ++C+  N   TA     +L  E+PS+  T+   E I  P      +  V 
Sbjct: 1621 DHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSV--TVLEGENITAPFLQPVTIQCVA 1678

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
                  +++W+K    +  T     I  V  R          D+  YTCV  +     K 
Sbjct: 1679 AGMPVPNLSWWKNGVSLVTTGGSLQIEKVDLR----------DEGNYTCVATNLAGEAKR 1728

Query: 1280 KVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS- 1337
             V + V  PP I        +   +  +L       P P   W    + I     +KP  
Sbjct: 1729 DVVLKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISWYRGRQPIS----SKPGL 1784

Query: 1338 -IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEID 1393
             + S    L IK+ + +DAG Y+    N  G ++++  + I   P     P  P  + ++
Sbjct: 1785 MVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLPGPVLLN 1844

Query: 1394 SSSINICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRF 1451
                 +C      TG  T ++ ++ +   +  T    ++        ++   +   +  +
Sbjct: 1845 EPVRLVC----NATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTY 1900

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
               AVN V       T + +          P++    +N++   N+ + L C    VP P
Sbjct: 1901 TCVAVNAVGEDRRDVTLQVHL--------PPSILGEEQNVSVVVNQSVTLECQSQAVPPP 1952

Query: 1512 KVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
             ++W +DG  L      +   +                Y C A N  G  E    + +  
Sbjct: 1953 VLSWRKDGHALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWV 2012

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             P  +   E        G    ++    GIP P++ W K+G  +  D            +
Sbjct: 2013 PPEFSFW-EPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRL 2071

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            + + + + S    YT E SN AG SS E  L+VY  P  P      +E+S
Sbjct: 2072 LYLGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVS 2121



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 80/316 (25%), Positives = 123/316 (38%), Gaps = 36/316 (11%)

Query: 527  VQFECQVEGYPRPQITWFRQTAII-KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            V   C   G P P ++W +  A + K    +++         L I +  P   G +TC A
Sbjct: 3520 VVLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRV----SPTGALEIEQALPIHTGRYTCTA 3575

Query: 586  KNAAGFASSTTELIVE----------------APLSDHGSEMTVXXXXXXXXXXXXADIL 629
            +NAAG A     L+V+                A   D G+ + +              ++
Sbjct: 3576 RNAAGVAHKHVILMVQGTGAQILSSGQLRISRASAEDAGNYLCIAKNPSGTALGKTRLVV 3635

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            + +PP            EGS  LL C    IPEP I W  K   +VP       I+    
Sbjct: 3636 Q-VPPVIKGGHSDLSAAEGSQALLPCIAQGIPEPHITWK-KDGFVVPSMEGKYTIQPS-- 3691

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L + N ++   GTYT +A N  G  S  + L I +     P        + +  G
Sbjct: 3692 ---GELLVKNSERRDAGTYTCIAENAAGHTSRRVHLSILS----LPTFTTLPGDLSLNHG 3744

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAE 808
            + + L     G+P P I+W  NN+ VK    + DG +   T+ +    + D G YT  AE
Sbjct: 3745 DRLWLRCTARGSPTPHISWMVNNRLVKEGVLEQDGGS---TLQRAAVTREDSGTYTCWAE 3801

Query: 809  NSEGIAETSAVITVEE 824
            N  G  +  + + V+E
Sbjct: 3802 NIVGKVQAVSFVHVKE 3817



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 123/612 (20%), Positives = 227/612 (37%), Gaps = 44/612 (7%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTA--EVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131
            L I +      G ++C   +E+ TA  EV V+      +T L+ + +         I+  
Sbjct: 1618 LRIDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEGENITAPFLQPVTIQCV 1677

Query: 1132 KGDALV---RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184
                 V    W+K+G  +       +T  G  Q  K+   DL D G Y+C      G +K
Sbjct: 1678 AAGMPVPNLSWWKNGVSL-------VTTGGSLQIEKV---DLRDEGNYTCVATNLAGEAK 1727

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFT 1243
               +L V  P  N    L    ++  NT A L        T  ++WY+ +  I       
Sbjct: 1728 RDVVLKVLVPP-NIEPGLVNKAVLE-NTSASLECLASGVPTPRISWYRGRQPISSKPGLM 1785

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYEREYRIKR 1301
            + SD   R L I++    D   Y CV  +   +++LK  + +  PP+I +       +  
Sbjct: 1786 VSSD--GRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLPGPVLL 1843

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
               V L+ +    P P   W+ +   +     +   I      LT+     TDAG Y   
Sbjct: 1844 NEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCV 1903

Query: 1362 LENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
              N  G    ++ + +   PS  G+  N+  + + S+ +  +         ++ +  +  
Sbjct: 1904 AVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTL--ECQSQAVPPPVLSWRKDGH 1961

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
             +     + + +       ++  +     R+   A+N+   S+       + V  E    
Sbjct: 1962 ALSPRPGVHL-SADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVW-VPPEFSFW 2019

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540
             P      + +       + L+C   G+P PK+TW +DG  + T   + E          
Sbjct: 2020 EP------RTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLY 2073

Query: 1541 XXXXXXX----YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAV 1595
                       Y C   N  G       + +   P +  S++  K+   +   E  +   
Sbjct: 2074 LGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGEVTLECE 2133

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
              G PPP V W K+G  +  D+   +  + +   +++++ + +H+ +YT  A N AG + 
Sbjct: 2134 ATGKPPPVVTWEKDGQLVTRDQ--GLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAE 2191

Query: 1656 VEVTLKVYDKPS 1667
                L V   PS
Sbjct: 2192 QRFDLSVLGNPS 2203



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 75/342 (21%), Positives = 138/342 (40%), Gaps = 37/342 (10%)

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
            TH + IL  ++ +D G YT    N  G A  +  + V  P   + + PL     +E+  K
Sbjct: 2287 THGLQILNAQE-QDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAK 2345

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
               T+ L       P P+ITWY++ +++SP   +    DG  +++   N     DSG Y 
Sbjct: 2346 VNSTLSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQI---NPTKAWDSGRYL 2402

Query: 906  CVASNSAGKSSHGARVTIDVEKV---------TFVKHLQKS---------YETEEGKTVI 947
            CVA+N AG+      V + V  +          F  H Q+           E  E     
Sbjct: 2403 CVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAY 2462

Query: 948  LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
            L C T+     +  WY + + +S ++   ++Q GR            D G   C   ++ 
Sbjct: 2463 LYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGR--VLQIPMVRSEDAGRYTCKASNEV 2520

Query: 1006 TSTMLVVKETI--PEFIR-----KLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIK 1057
                L  +  +  P  I+      +++  V       L+ + + + T  + W R+G    
Sbjct: 2521 GEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFI 2580

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            P  +K+   + G + ++ + + +  D   Y C+  + + ++E
Sbjct: 2581 P-SSKHQALEDGQVLQVSVADAA--DSASYMCVAENSAGSSE 2619



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 95/465 (20%), Positives = 173/465 (37%), Gaps = 39/465 (8%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C+  G P+P + W +    +   +  + Y    + ++LV+ +   +D   F C+  N AG
Sbjct: 3431 CEARGSPKPHVVWKKNGQTLSLDRHQEAYRLLPS-SSLVLTDPDLQDTAQFECLVSNDAG 3489

Query: 591  FASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTFS-KKPKAQYVD 646
                   + V  P  ++D  ++ TV                 G+P P  S  K  AQ   
Sbjct: 3490 ETRRLFWVTVYVPPTIADDRTDFTVTKMAPVVLTCHTT----GVPTPVVSWSKGGAQLGK 3545

Query: 647  EGSDI------LLEC-RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV--LKI 697
             GS         LE  + + I         +    V  +++ + ++       S   L+I
Sbjct: 3546 RGSGYRVSPTGALEIEQALPIHTGRYTCTARNAAGVAHKHVILMVQGTGAQILSSGQLRI 3605

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
            +       G Y  +A N  G A    + K +   + PP +      +   +G   +L   
Sbjct: 3606 SRASAEDAGNYLCIAKNPSGTA----LGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPCI 3661

Query: 758  VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
              G P P ITW K+   V ++  K         ++K  + +D G YT  AEN+ G     
Sbjct: 3662 AQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAAGHTSRR 3721

Query: 818  AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
              +++          P F     ++++     + L      +P P I+W  NN ++   E
Sbjct: 3722 VHLSI-------LSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLV--KE 3772

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
             + +   G  ++      +   DSG Y C A N  GK    A   + V++   ++    S
Sbjct: 3773 GVLEQDGGSTLQRAAVTRE---DSGTYTCWAENIVGKVQ--AVSFVHVKEAPALQGEASS 3827

Query: 938  YETE-EGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEG 979
            +  E  G +  L+C      +   +W  +   +    H+  +Q G
Sbjct: 3828 HLVELLGDSARLDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNG 3872



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 64/264 (24%), Positives = 109/264 (41%), Gaps = 23/264 (8%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXX 1539
            P +  P +N+T  P E   L+C         +TW RD + L  +  +             
Sbjct: 430  PQLASP-QNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLANLSLEISG 488

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y+C+A N +G    S  + I++ P I+I+     +    G E  ++    G 
Sbjct: 489  IIPSDGGKYQCLASNANGITRASVWLLIREPPQISINTSS--RHFSQGVELRISCTASGY 546

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            PPP + W  N   +  D  + +   +    + I+ +    +  Y+ +A+N  GT    VT
Sbjct: 547  PPPHISWRHNDQTIGMDGRFLV---DDQGTLIIQSVTPEDAGNYSCQATNEVGTDEQTVT 603

Query: 1660 LKVYDKPS-KPEGPVIMREISRESVTIEWK----PP----LDDGGLELTKYAIEKHEPDN 1710
            L   + PS     PV++  I  E+V +E K    PP       GGLE+    I   E  +
Sbjct: 604  LFYTEPPSVSALRPVVLAPIGEEAV-LECKASGVPPPRVIWYRGGLEM----ILAPEVAH 658

Query: 1711 NRWIKVADV-DRDVETYCIQKLNE 1733
               +++ +V +RD   Y  + +NE
Sbjct: 659  TGTLRIQEVQERDAGNYICKAVNE 682



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 77/309 (24%), Positives = 122/309 (39%), Gaps = 29/309 (9%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            L+I N ++   G YT V  N  GEA       VL   +  K+ P     +K +  +   +
Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVNST 2349

Query: 752  VILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            + L  +    P PTITW K+ +   P   L   +DG    +  + P K  D G Y   A 
Sbjct: 2350 LSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADG---RLLQINPTKAWDSGRYLCVAT 2406

Query: 809  NSEGIAETSAVITVEEPT--EENAEP-PLFINRFQEITVK----------EKGTIKLVAR 855
            N  G  +    + V+ P   ++  +P   F    QE  ++          E     L   
Sbjct: 2407 NVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCD 2466

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
                P P +TWY++++ +S  E I+    G  + L I  V SE D+G Y C ASN  G+ 
Sbjct: 2467 TNAVPPPQLTWYKDDQPLSDIEGISV-LQGGRV-LQIPMVRSE-DAGRYTCKASNEVGED 2523

Query: 916  SHGARVTIDVEKVT--FVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
                 + +    V     + L +        TV L+CQ   + T    W  N        
Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSS 2583

Query: 972  HREIIQEGR 980
              + +++G+
Sbjct: 2584 KHQALEDGQ 2592



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 8/188 (4%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXX 1539
            P ++    +++        L CI  G+P+P +TW +DG  + +   K T +         
Sbjct: 3639 PVIKGGHSDLSAAEGSQALLPCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKN 3698

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y CIA N  G       + I   P  T    D+   H  GD   +     G 
Sbjct: 3699 SERRDAGTYTCIAENAAGHTSRRVHLSILSLPTFTTLPGDLSLNH--GDRLWLRCTARGS 3756

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P + W  N N+L  +    +  ++  S ++   + R  S  YT  A N  G       
Sbjct: 3757 PTPHISWMVN-NRLVKE---GVLEQDGGSTLQRAAVTREDSGTYTCWAENIVGKVQAVSF 3812

Query: 1660 LKVYDKPS 1667
            + V + P+
Sbjct: 3813 VHVKEAPA 3820



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 59/249 (23%), Positives = 99/249 (39%), Gaps = 27/249 (10%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I N +   + R+     NEV  +  +   E       +K   P  E  +K +  + N  +
Sbjct: 2292 ILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISK-DDPLDEFSVKEVKAKVNSTL 2350

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
             L C    +P P +TWY+DG+ +      +   +                Y C+A N  G
Sbjct: 2351 SLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQINPTKAWDSGRYLCVATNVAG 2410

Query: 1558 EVETSCVVGIQQKPV---ITISNEDIKQKHKVGDEWLVTAVIE----------------- 1597
            E +    V +Q  P+   I   NE  +  H+  +E L   V+E                 
Sbjct: 2411 EDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQ--EEELRGGVLEYREIVENNPAYLYCDTN 2468

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
             +PPP++ WYK+   L +D E  I+  +   V++I  ++   + +YT +ASN  G   + 
Sbjct: 2469 AVPPPQLTWYKDDQPL-SDIE-GISVLQGGRVLQIPMVRSEDAGRYTCKASNEVGEDWLH 2526

Query: 1658 VTLKVYDKP 1666
              L V   P
Sbjct: 2527 YELLVLTPP 2535



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 4/87 (4%)

Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
           +H   G  ++  C   GYP P I+W      I    D +   DD    TL+I+ V PEDA
Sbjct: 529 RHFSQGVELRISCTASGYPPPHISWRHNDQTI--GMDGRFLVDDQG--TLIIQSVTPEDA 584

Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLS 605
           G ++C A N  G    T  L    P S
Sbjct: 585 GNYSCQATNEVGTDEQTVTLFYTEPPS 611



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 6/174 (3%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            L C     P PK+ W+R+G  L+    T   EN                Y C+A N  G 
Sbjct: 3247 LECPVEADPPPKIEWHREGVLLQADAHTLFLENGRFLQLQALDTSDSGDYNCVASNAAGS 3306

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
                  V I   P I      +     V +  L+     G+P   V W K+G  L     
Sbjct: 3307 TSLPFSVEIHMAPTIQPGPSVVNVS--VNETALLPCKTRGLPVSLVSWRKDGIPLVPGSP 3364

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                  + +  +RI+ +    S  Y  +ASN+AG+      L+V++ P+   GP
Sbjct: 3365 RLEFLSDGS--LRIQPVYPQDSGYYLCQASNSAGSDRQGRELRVFEPPTIAPGP 3416



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 3/142 (2%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
            L I + + +D   Y C+  +   T   K   VV+ PP I     +     GS   L    
Sbjct: 3603 LRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPCIA 3662

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
            Q  P+P+  W  +  ++   +  K +I   S  L +K  E  DAG Y    EN  GH   
Sbjct: 3663 QGIPEPHITWKKDGFVVPSMEG-KYTIQP-SGELLVKNSERRDAGTYTCIAENAAGHTSR 3720

Query: 1372 EMNVTILDKPSPPGKPNILEID 1393
             ++++IL  P+    P  L ++
Sbjct: 3721 RVHLSILSLPTFTTLPGDLSLN 3742



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +GS     C  +G P P ITW ++   + PS + +  Y       L+++     DAGT+T
Sbjct: 3652 EGSQALLPCIAQGIPEPHITW-KKDGFVVPSMEGK--YTIQPSGELLVKNSERRDAGTYT 3708

Query: 583  CVAKNAAGFASSTTELIV 600
            C+A+NAAG  S    L +
Sbjct: 3709 CIAENAAGHTSRRVHLSI 3726



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 76/339 (22%), Positives = 124/339 (36%), Gaps = 51/339 (15%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI-----ITRLQNQKVNKGNKAT 1125
            L I N    D G Y+C++ +E   A       V +PP I     +     ++V     +T
Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVNST 2349

Query: 1126 FEIELTKG---DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              +E          + W+KDG  +   N + L  DG+   L+I      D+G Y C   N
Sbjct: 2350 LSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGR--LLQINPTKAWDSGRYLCVATN 2407

Query: 1183 -----SKCTAILT--------VEEPSINFTLR---------LPEFILVPANTDAYL---T 1217
                  K   +L         + +P+  F +          + E+  +  N  AYL   T
Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDT 2467

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
              +P   L  TWYK    + D E  +++     R L I     +D   YTC   +     
Sbjct: 2468 NAVPPPQL--TWYKDDQPLSDIEGISVLQG--GRVLQIPMVRSEDAGRYTCKASNEVGED 2523

Query: 1278 KLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKC 1331
             L  E++   P ++     +   E  +   S V L       P P   W+ N    I   
Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSS 2583

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
            KH   +++     L +   +  D+  Y    EN+ G ++
Sbjct: 2584 KH--QALEDGQV-LQVSVADAADSASYMCVAENSAGSSE 2619



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 72/281 (25%), Positives = 111/281 (39%), Gaps = 37/281 (13%)

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE---EPSINFTLRLP 1203
            + H +L++ G    L+I +    DAG Y+C V N    A+    VE    PSI+    L 
Sbjct: 2277 TKHYKLSVLGT-HGLQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLD 2335

Query: 1204 EFIL--VPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
            EF +  V A  ++ L++E     +    +TWYK   ++    +  L++D   R L I   
Sbjct: 2336 EFSVKEVKAKVNSTLSLECESWAMPPPTITWYKDGQLVSPDNRLHLLAD--GRLLQINPT 2393

Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP---KIVD----YE------------REYR 1298
               D   Y CV  +          V V+ PP   KI D    +E             EYR
Sbjct: 2394 KAWDSGRYLCVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453

Query: 1299 -IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
             I   +   L  D  A P P   W  + + +   +    S+      L I  V + DAG 
Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGI--SVLQGGRVLQIPMVRSEDAGR 2511

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
            Y  +  N  G   +   + +L  P   G P  L ++  ++N
Sbjct: 2512 YTCKASNEVGEDWLHYELLVLTPPVIQGDPEEL-VEEVTVN 2551



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 41/158 (25%), Positives = 63/158 (39%), Gaps = 11/158 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PTF+  P    ++ G  + L C     P P I+W+     +   E +   +E D     S
Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLV--KEGV---LEQDGG---S 3781

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L+   V +   GTYT  A N  G+      + +K   + P    E    ++   G+S  
Sbjct: 3782 TLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVK---EAPALQGEASSHLVELLGDSAR 3838

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            L     G+P P I W K+  PV +   K      S+ I
Sbjct: 3839 LDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNGSLAI 3876



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 48/156 (30%), Positives = 62/156 (39%), Gaps = 16/156 (10%)

Query: 452  NQDWWYVQKHLTEEKGWVPAQY--LMDENNYTQYLQKKLNE-KIDK-LPVFEKPTSEEQS 507
            N  WW     L    G +  +   L DE NYT        E K D  L V   P  E   
Sbjct: 1685 NLSWWKNGVSLVTTGGSLQIEKVDLRDEGNYTCVATNLAGEAKRDVVLKVLVPPNIE--- 1741

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
              P  V K   ++T    +   EC   G P P+I+W+R    I  S+   M   D  V  
Sbjct: 1742 --PGLVNKAVLENT----SASLECLASGVPTPRISWYRGRQPIS-SKPGLMVSSDGRV-- 1792

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            L I+     DAG++ CVA N AG +     L +  P
Sbjct: 1793 LRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVP 1828



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 52/233 (22%), Positives = 93/233 (39%), Gaps = 18/233 (7%)

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLT 1217
            +L+I     +DAG Y C   N   TA+    L V+ P +   ++     L  A     L 
Sbjct: 3602 QLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPV---IKGGHSDLSAAEGSQALL 3658

Query: 1218 VEIPDETLD--VTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
              I     +  +TW K   V+   E K+T+    +   L+++     D   YTC+  +A 
Sbjct: 3659 PCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGE---LLVKNSERRDAGTYTCIAENAA 3715

Query: 1275 STTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
              T  +V + +   P       +  +  G  + L    +  P P+  W+VN++++K+   
Sbjct: 3716 GHTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGVL 3775

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             +       ++L    V   D+G Y    EN  G       V + + P+  G+
Sbjct: 3776 EQDG----GSTLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGE 3824



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 510 PIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           P  V  LRP    P G     EC+  G P P++ W+R         +  +  +  +  TL
Sbjct: 609 PPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRG------GLEMILAPEVAHTGTL 662

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            I+EV   DAG + C A N  G AS+   L V
Sbjct: 663 RIQEVQERDAGNYICKAVNELGAASADIRLEV 694



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 39/192 (20%), Positives = 72/192 (37%), Gaps = 10/192 (5%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PPT +  P    +   +   L C     P+P + W   G+ +  D +     E+   +  
Sbjct: 3409 PPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQTLSLDRHQ----EAYRLLPS 3464

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            S L +T+        +  +  N  GE      + +      PP + +      V +   V
Sbjct: 3465 SSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYV----PPTIADDRTDFTVTKMAPV 3520

Query: 753  ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            +L+    G P P ++W K    + K         T ++ I +   +   G YT  A N+ 
Sbjct: 3521 VLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVSPTGALEIEQALPI-HTGRYTCTARNAA 3579

Query: 812  GIAETSAVITVE 823
            G+A    ++ V+
Sbjct: 3580 GVAHKHVILMVQ 3591



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 6/81 (7%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +   C   G P P I+W     ++K         + D  +TL    V  ED+GT+TC
Sbjct: 3744 GDRLWLRCTARGSPTPHISWMVNNRLVKEG-----VLEQDGGSTLQRAAVTREDSGTYTC 3798

Query: 584  VAKNAAGFASSTTEL-IVEAP 603
             A+N  G   + + + + EAP
Sbjct: 3799 WAENIVGKVQAVSFVHVKEAP 3819



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/129 (19%), Positives = 46/129 (35%), Gaps = 1/129 (0%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541
            PT      +++    + + L C   G P P ++W  + + +K      +           
Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGVLEQDGGSTLQRAAVT 3789

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C A N  G+V+    V +++ P +            +GD   +     G P 
Sbjct: 3790 REDSGTYTCWAENIVGKVQAVSFVHVKEAPALQ-GEASSHLVELLGDSARLDCAARGDPA 3848

Query: 1602 PEVIWYKNG 1610
            P + W K+G
Sbjct: 3849 PVIRWIKDG 3857



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 23/275 (8%)

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL 948
            +L I+   +E D+G+Y C+A N +G +    R+ + V  V  +K         EG   +L
Sbjct: 3602 QLRISRASAE-DAGNYLCIAKNPSGTALGKTRLVVQVPPV--IKGGHSDLSAAEGSQALL 3658

Query: 949  EC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
             C  Q        W  +   +  M+ +  IQ               D G   CI ++   
Sbjct: 3659 PCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPS--GELLVKNSERRDAGTYTCIAENAAG 3716

Query: 1007 STMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNK 1062
             T   V  +I   P F     D  +   D   L      S T  + W  +  ++K  +  
Sbjct: 3717 HTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVK--EGV 3774

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQNQKV 1118
             + +    +++  +      D G Y+C    I+      + V V E P        +   
Sbjct: 3775 LEQDGGSTLQRAAVTR---EDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGEASSHLVE 3831

Query: 1119 NKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNH 1151
              G+ A  +    +GD   ++RW KDG  +  S+H
Sbjct: 3832 LLGDSARLDCA-ARGDPAPVIRWIKDGLPVLSSHH 3865



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 5/127 (3%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
            Y C A N  G  +   ++ +   P I  T   +      +VGD  ++    + +P P + 
Sbjct: 2645 YTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDTLPEPVIT 2704

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            WYKNG ++  D++  + T      + I  ++ +    Y+ + SN  G  ++   + +   
Sbjct: 2705 WYKNGQQIALDQQ--VQTLLDGQKLEIVNVQVADKGLYSCKVSNIVG-EAIRTFVLIVQV 2761

Query: 1666 PSKPEGP 1672
            P   E P
Sbjct: 2762 PPIFENP 2768



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T    CQV       +TW R   ++  S    +   +    +L I  + P D G + C
Sbjct: 443 GETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLAN---LSLEISGIIPSDGGKYQC 499

Query: 584 VAKNAAGFASSTTELIVEAP 603
           +A NA G   ++  L++  P
Sbjct: 500 LASNANGITRASVWLLIREP 519



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            +V  ECQ +  P P ++W +    + P     +  D      L +     +D G +TC A
Sbjct: 1939 SVTLECQSQAVPPPVLSWRKDGHALSPRPGVHLSADG---VLLQVERAEVQDVGRYTCEA 1995

Query: 586  KNAAGFASSTTELIVEAP 603
             N AG +     L V  P
Sbjct: 1996 LNKAGRSEKHYNLNVWVP 2013



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
            +L I   S  D G Y CI ++ S TA      VV++PP I     +    +G++A     
Sbjct: 3602 QLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPC- 3660

Query: 1130 LTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            + +G  +  + W KDG  +  S   + TI     +L + + +  DAG Y+C   N+
Sbjct: 3661 IAQGIPEPHITWKKDGFVVP-SMEGKYTIQ-PSGELLVKNSERRDAGTYTCIAENA 3714


>UniRef50_Q8N9C0 Cluster: Immunoglobulin superfamily member 22; n=9;
            Mammalia|Rep: Immunoglobulin superfamily member 22 - Homo
            sapiens (Human)
          Length = 903

 Score =  186 bits (453), Expect = 6e-45
 Identities = 167/786 (21%), Positives = 331/786 (42%), Gaps = 51/786 (6%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
            P+ +E  + +   +G+  +  A+V GN +P I+W    K    +P K        +I K 
Sbjct: 67   PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW----KRESGIPIKESAKIFYDSINKE 122

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
              +K E + +  ++N + IA       +   +       L +   QE     K   K + 
Sbjct: 123  HVLKLEPLTSDDSDNYKCIASNDHADAIYTVS-------LLVTEGQE-----KMDFKKML 170

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            +    P P     +  ++ +  E +        I   +   D E    +Y         +
Sbjct: 171  KKRAPPAPK---KKQKKVANEKEML-------EILSKVPKKDFEKVCMEYGFTDFRGLLR 220

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEIS--- 968
                 +  ++VE +  +K L+   ET+   TV+ +C        V   W    + +    
Sbjct: 221  KLKEMKKKVEVEAIRILKPLEDK-ETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY 279

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028
             +   ++ Q G             D G+    V D+  S  L V +   +F+ +++  +V
Sbjct: 280  SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKV 339

Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF--EKRGHIRKLYIRNTSVHDEGE 1086
             E+  A+ E+ ++ +  + VW+ +G+ +K + +KY+    + G    L I++  + D GE
Sbjct: 340  TERQTAVFEIRLSKKEPNFVWKFNGKELK-RDDKYEITVSEDGLTHTLKIKDARLSDSGE 398

Query: 1087 YSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI 1146
            +S    +    A++TV  +P + ++ L+N +V + ++A  E ELT  D  +RW KDG  +
Sbjct: 399  FSAEAGNLVQKAQLTVDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLL 458

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEY---SCEVGNSK---CTAILTVEEPSINFTL 1200
                   +  +GK+ +L I D  L D GEY   + + G+      TAI+TVEE       
Sbjct: 459  MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS 518

Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
             + + +     + A L V + DE ++  W K    I D     ++       LI      
Sbjct: 519  GMSD-VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGP 577

Query: 1261 DDQCEYTCVLLDAKSTTKLKV-EVVEFPPKIVDYEREYRI--KRGSDVTLLVDYQAFPQP 1317
            + + +YT      +S   + + +     P +++    + I  K G    + V ++  P P
Sbjct: 578  EHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLP 637

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               W  +   + + +          A LTI      D+G+  L+L+N+ G A   +++++
Sbjct: 638  KVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435
            L+ P    +P + ++   ++ I W+ P   G + ++ Y+VE ++  +  W+ V    I  
Sbjct: 698  LEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 757

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
            T+ ++  L  ++ Y FR  AVN+      S  +    V+ +  ++ P + + L +++   
Sbjct: 758  TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSS--SVVAKDPVKPPGLVQDL-HVSDSS 814

Query: 1496 NEDIEL 1501
            N  I L
Sbjct: 815  NSSISL 820



 Score =  109 bits (263), Expect = 6e-22
 Identities = 139/666 (20%), Positives = 259/666 (38%), Gaps = 41/666 (6%)

Query: 1218 VEIPDETLDVTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
            +E+ D  + + W K    +       K+ +     K  L+I     +D   Y+  + D +
Sbjct: 257  MELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR 316

Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
             + +L V  ++ P K +   +  ++         +      +PN  W  N K +K+    
Sbjct: 317  MSAELTV--LDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKY 373

Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
            + ++  D  + +L IK    +D+G +     N    A + ++   +   S      + E 
Sbjct: 374  EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTVDRIPIKFVSNLKNVRVKER 433

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
              + +     E E T     + +  + Q +   T++       + +  I++ + +    +
Sbjct: 434  SRACL-----ECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488

Query: 1452 RAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
               A+ + D       TEYY   I   + +  TV+  + ++        EL C+     +
Sbjct: 489  TVVAMQDGD------PTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEK 541

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQQ 1569
             +  W +DGK++         +               ++    F   G  E+   V I  
Sbjct: 542  VEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG-TESEASVFIAD 600

Query: 1570 KPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             P I  S  +    H    KVG    +     G P P+V WYK+G ++  ++  ++   E
Sbjct: 601  PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
              +++ I    R  S    ++  N  G+++  + L V + P     P +  ++++E+VTI
Sbjct: 661  DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLEPPGFASQPQV-TDVTKEAVTI 719

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQ 1744
             W  P  DGG  +  Y +E+ +  +N W+ V + D    T C +  L E+ EY FRVIA 
Sbjct: 720  TWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NKDPIQGTKCTVDGLLEDTEYEFRVIAV 778

Query: 1745 NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
            N  G  + ++ S  +V K  +  P             N S+ + W   E   G P   Y 
Sbjct: 779  NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS-SNSSISLAW--REPAEGDPPSGYI 835

Query: 1804 VEIKQEG-KKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
            +E++ E  K+W              +  L     Y FRI A NE G   P   D  +   
Sbjct: 836  LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--- 892

Query: 1861 KTLTPP 1866
            + + PP
Sbjct: 893  RAMPPP 898



 Score =  109 bits (261), Expect = 1e-21
 Identities = 183/872 (20%), Positives = 319/872 (36%), Gaps = 76/872 (8%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKD-GSEIQFSNHIQLTIDGKKQKL 1163
            PE + + Q     +G+KA F   + +G+A   + W ++ G  I+ S  I      K+  L
Sbjct: 67   PEFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVL 125

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
            K+     DD+  Y C   N    AI TV              ++            +   
Sbjct: 126  KLEPLTSDDSDNYKCIASNDHADAIYTVS------------LLVTEGQEKMDFKKMLKKR 173

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-LKVE 1282
                   K+K V  + E   ++S V K+    + C E    ++  +L   K   K ++VE
Sbjct: 174  APPAPKKKQKKVANEKEMLEILSKVPKKDFE-KVCMEYGFTDFRGLLRKLKEMKKKVEVE 232

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVD-YQAFPQPNDE--WIVNSKIIKKCKHTKPSID 1339
             +     + D E +       D T++ D       PN +  WI  ++ ++  +++    D
Sbjct: 233  AIRILKPLEDKETKV------DTTVVFDCIMELKDPNVKMIWIKGTEPLR-IQYSLGKYD 285

Query: 1340 SKSAS----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP---PGKP-NILE 1391
             K       L I  V   DAGIY L +    G   +   +T+LD+P       KP  + E
Sbjct: 286  VKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE 341

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYR 1450
              ++   I   + E   N    +   E +  D  E I+V     T T  I++ + + S  
Sbjct: 342  RQTAVFEIRLSKKEP--NFVWKFNGKELKRDDKYE-ITVSEDGLTHTLKIKDARLSDSGE 398

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            F A A N V  +  +      K +             LKN+  +      L C       
Sbjct: 399  FSAEAGNLVQKAQLTVDRIPIKFVSN-----------LKNVRVKERSRACLECELTS-KD 446

Query: 1511 PKVTWYRDGKKLKTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVE--TSCV 1564
              + W +DG+ L        N    R               Y  +A  D    E  ++ +
Sbjct: 447  VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            V ++++ + T+ +  +   H          V+      E +W K+G ++ +     I  +
Sbjct: 507  VTVEER-LATVKS-GMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ 564

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
                 +    +   H  KYT  A  T   +SV +       PS  E         +   T
Sbjct: 565  GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHT 624

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
               K P     L    +  +  E      + + +   D     I         +  +  +
Sbjct: 625  AHIKVPFRGKPLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLK 683

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
            N  G + A       +  ++  P           +  E+V ITW    ++GG+P++ Y V
Sbjct: 684  NDHGSATA------TLHLSVLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 737

Query: 1805 EIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            E +++G   W           +  +  L  +T Y+FR+ A N+ G   P      +    
Sbjct: 738  ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 797

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
             + PP   ++  VS+S++ S++L W EP    G P + YI+E +    K W+K   +  S
Sbjct: 798  PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 855

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
               + +  + E+ +  FRI A N  GV  P E
Sbjct: 856  GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 887



 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 117/524 (22%), Positives = 215/524 (41%), Gaps = 51/524 (9%)

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKPVKALPTKSDGD- 785
            K  E E  ++++PL+    +   +V+    + + +P   + W K  +P++   +    D 
Sbjct: 227  KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDV 286

Query: 786  ----THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
                T  + ++    + D G+Y+L    S G    SA +TV +      EP  F+   + 
Sbjct: 287  KQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLD------EPLKFLGEMKP 336

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEI 899
            + V E+ T     R+++   P+  W  N + +   +   IT + DG    L I +     
Sbjct: 337  VKVTERQTAVFEIRLSKKE-PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLS- 394

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST 958
            DSG++   A N   K    A++T+D   + FV +L K+   +E     LEC+ TS  V+ 
Sbjct: 395  DSGEFSAEAGNLVQK----AQLTVDRIPIKFVSNL-KNVRVKERSRACLECELTSKDVTL 449

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI-VKDQE-----TSTMLVV 1012
            +W  + + +       +  EG+            D G    + ++D +     ++ ++ V
Sbjct: 450  RWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTV 509

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            +E +      + D        A L V +N E  + VW +DG+ I          K+G + 
Sbjct: 510  EERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPG-MQIVKQGAVH 568

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP---PEIITRLQNQ--KVNKGNKATFE 1127
            KL   +     EG+Y+   +     A V + + P   P ++  L      V  G+ A  +
Sbjct: 569  KLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIK 628

Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
            +   +G  L  V W+KDG E+     + +     +  L I +C  +D+G    ++ N   
Sbjct: 629  VPF-RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG 687

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            +A  T+        L  P F   P  TD      +  E + +TW
Sbjct: 688  SATATLHLS----VLEPPGFASQPQVTD------VTKEAVTITW 721



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 52/204 (25%), Positives = 87/204 (42%), Gaps = 2/204 (0%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            L PP       V++ T  +VT+ W  P  +GG+P+  YI+E +      W  +       
Sbjct: 698  LEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 757

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
             +  ++ + E  E  FR+ A N  G   P+   S  + K    P      L +    ++ 
Sbjct: 758  TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 817

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            +  +W  P    G P  GY + +R      W +  K+ ++   + +  L E   Y  RI 
Sbjct: 818  ISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 875

Query: 2043 ARNEIGLSEPLESDEPFKVIPGEG 2066
            A NE G+ EP+E D+  + +P  G
Sbjct: 876  AVNEAGVGEPVELDKGVRAMPPPG 899



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 18/327 (5%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           ++ IP  F    K   V E S   LEC L +  +  + W   G+ ++     S+  E   
Sbjct: 414 VDRIPIKFVSNLKNVRVKERSRACLECELTS-KDVTLRWKKDGQLLMHGTKYSMNHEGKR 472

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
               + L I + +    G YTVVA+ ++G+ +      I T E+    V   +  +    
Sbjct: 473 ----AELIIEDAQLSDGGEYTVVAM-QDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTL 805
           G    L   V+ + +    W K+ K +  LP       G  H + I      + EG YT 
Sbjct: 528 GSPAELCV-VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL-IFPSMGPEHEGKYTF 585

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +A+ +E  A   +V   + PT + +   L       ITVK   T  +       P+P +T
Sbjct: 586 RAKGTESEA---SVFIADPPTIDPSV--LEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           WY++   ++  E ++     +   L I+N   E DSG       N  G ++    +++ +
Sbjct: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVRE-DSGLILLKLKNDHGSATATLHLSV-L 698

Query: 926 EKVTFVKHLQKSYETEEGKTVILECQT 952
           E   F    Q +  T+E  T+     T
Sbjct: 699 EPPGFASQPQVTDVTKEAVTITWNAPT 725



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 2/107 (1%)

Query: 1948 VSLPTESQSVRLEKHATVPSPP--TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005
            + L  +  S     H +V  PP   +  ++  V    V  +W  P  DGGAP+LGY +  
Sbjct: 680  LKLKNDHGSATATLHLSVLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 739

Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            R     +W+ V K  +   K  +  L E+  Y  R+ A N+ G  +P
Sbjct: 740  RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQP 786



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVA-T 567
           P FVEK +P   P+G    F  +V+G  +P I+W R++ I IK S   +++YD  N    
Sbjct: 67  PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSINKEHV 124

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           L +  +  +D+  + C+A N    A  T  L+V
Sbjct: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 7/158 (4%)

Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
           S   TH  T  +  K+  E V   K   S  I E  +++T           P F+ + Q 
Sbjct: 19  SSSTTHVQTFSQTTKIVGEEVVRRK---SSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQP 75

Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSETITQNFDGENIELVITNVDSEID 900
           +T  E       ARV  N  P I+W R + I I  S  I  +   +   L +  + S+ D
Sbjct: 76  VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSD-D 134

Query: 901 SGDYKCVASNSAGKSSH--GARVTIDVEKVTFVKHLQK 936
           S +YKC+ASN    + +     VT   EK+ F K L+K
Sbjct: 135 SDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKK 172



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 45/196 (22%), Positives = 86/196 (43%), Gaps = 15/196 (7%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           P  F  + K   V E    + E RL +  EP+  W F G+E+  D+   + +  D   + 
Sbjct: 327 PLKFLGEMKPVKVTERQTAVFEIRL-SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTH- 384

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             LKI + +    G ++  A N   +A L       T ++ P + +  LK++ V++    
Sbjct: 385 -TLKIKDARLSDSGEFSAEAGNLVQKAQL-------TVDRIPIKFVSNLKNVRVKERSRA 436

Query: 753 ILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            L  ++      T+ W K+ + +      + +     +  I++  ++ D G YT+ A   
Sbjct: 437 CLECELTSKD-VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD 495

Query: 811 EGIAE--TSAVITVEE 824
               E  ++A++TVEE
Sbjct: 496 GDPTEYYSTAIVTVEE 511



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T   +    G P P++TW++    +   +   M   +D  A L I     ED+G    
Sbjct: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ-ALLTISNCVREDSGLILL 680

Query: 584 VAKNAAGFASSTTELIVEAP 603
             KN  G A++T  L V  P
Sbjct: 681 KLKNDHGSATATLHLSVLEP 700



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 5/117 (4%)

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEI-IKPK-KNKY 1063
            S+ +   +++PEF+ K Q     E D A+    +       + W+R+  I IK   K  Y
Sbjct: 57   SSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFY 116

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
            D   + H+ KL     +  D   Y CI  ++   A  TV  L  E   ++  +K+ K
Sbjct: 117  DSINKEHVLKL--EPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171


>UniRef50_UPI0000F33BB2 Cluster: Connectin; n=1; Bos taurus|Rep:
            Connectin - Bos Taurus
          Length = 473

 Score =  185 bits (450), Expect = 1e-44
 Identities = 111/365 (30%), Positives = 179/365 (49%), Gaps = 13/365 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLEN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            I+G P PEV W K+   L+N  + E  I + +  + + +K+  R  S  Y ++A N AG 
Sbjct: 114  IKGRPAPEVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSYILKAKNVAGE 173

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
             SV V +KV D+P  PEGP+++  ++ E  T+ WKPPL DGG ++  Y +E+ E     W
Sbjct: 174  KSVTVNVKVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW 233

Query: 1714 IKVADVDRDVETY-C-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
                 VD +V+T  C   K+ +  EY+FRV A N  G  +ALES P++ + A  +P    
Sbjct: 234  ---TVVDANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHPVIARFA-SLPD-AP 288

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW---KXXXXXXXXXARIQ 1827
                   +   +V + W     +GGS ++ Y +E K ++  +W              ++ 
Sbjct: 289  GRPEVTDVTRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTRVNKDHVVYDTRLKVT 348

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
             L     YQFR+ A N  G S P  + + I+  +    P  P    + + +   +TL W 
Sbjct: 349  GLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPETLQIFDVSREGMTLTWY 408

Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
             PE +GGS +T YI+E K V+   W ++  V  ++  +    + E  E   R++A N  G
Sbjct: 409  PPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAVNVRG 468

Query: 1948 VSLPT 1952
               P+
Sbjct: 469  TGKPS 473



 Score =  122 bits (293), Expect = 1e-25
 Identities = 121/485 (24%), Positives = 206/485 (42%), Gaps = 25/485 (5%)

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
            +DI  + K    + VT   EGI      W KNG ++++     + TK+ T  + I+ +  
Sbjct: 3    KDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHF 59

Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE-ISRESVTIEWKPPLDDGG- 1695
              +++YT  A     T+++ V ++    P       + R  + R  ++I    P+     
Sbjct: 60   GDAAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPA 119

Query: 1696 --LELTKYAIE-KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
              +  TK  I  K+  +    IK  D    +      +++    Y+ +  A+N  G    
Sbjct: 120  PEVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSG-SYILK--AKNVAG---- 172

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
             E    V    LD P           +  E   + W P  ++GGS II+Y VE ++  + 
Sbjct: 173  -EKSVTVNVKVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 231

Query: 1813 -WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
             W            +  K+     Y FR+ A N+ G      S     I +  + P  P 
Sbjct: 232  VWTVVDANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHP--VIARFASLPDAPG 289

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-- 1928
               V++ T  +V+L W+ P  +GGS +  YIIE K  K   WT+ V     V++  ++  
Sbjct: 290  RPEVTDVTRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTR-VNKDHVVYDTRLKVT 348

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
             + E  +  FR++A N  G S P+E+ + +   + + +P PP   L+I  V    +  +W
Sbjct: 349  GLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPET-LQIFDVSREGMTLTW 407

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              PE DGG+ + GY +  ++V    W+ V KV V   ++    L E   Y  R+ A N  
Sbjct: 408  YPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAVNVR 467

Query: 2048 GLSEP 2052
            G  +P
Sbjct: 468  GTGKP 472



 Score =  103 bits (247), Expect = 5e-20
 Identities = 73/258 (28%), Positives = 113/258 (43%), Gaps = 8/258 (3%)

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            V +  E +   W K    I+ T++  + +     +L IR     D  EYT V   A ST 
Sbjct: 17   VTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGDAAEYTFVAGKATSTA 76

Query: 1278 KLKVEVV-EFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
             L VEV  E  P      +  R   ++ G  + + V  +  P P   W  ++  +K   +
Sbjct: 77   TLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN 136

Query: 1334 TKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
             +  I S   + SL++K     D+G Y L+ +N  G   V +NV +LD+P PP  P ++ 
Sbjct: 137  IENKIKSTDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKVLDRPGPPEGPIVIS 196

Query: 1392 -IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSY 1449
             + +    + W  P   G S II Y+VE +E     W  V  N+         +   + Y
Sbjct: 197  GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLGCKTTKIIKGNEY 256

Query: 1450 RFRAYAVNEVDISDASET 1467
             FR  AVN+  I DA E+
Sbjct: 257  IFRVRAVNKYGIGDALES 274



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 84/405 (20%), Positives = 162/405 (40%), Gaps = 28/405 (6%)

Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            L++    + +  TFE+ +       +W K+G EI+ ++  Q+        L I +    D
Sbjct: 2    LKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGD 61

Query: 1173 AGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPEFILVPANTDAYLTVEIPDETL-D 1226
            A EY+   G +  TA L VE      P       L   ++V A     + V I      +
Sbjct: 62   AAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPE 121

Query: 1227 VTWYKKKSVIEDTEKFT--LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            VTW K    +++       + S     +L ++     D   Y   +L AK+    K   V
Sbjct: 122  VTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSY---ILKAKNVAGEKSVTV 178

Query: 1285 EFPPKIVDY----EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSI 1338
                K++D     E    I   +     + ++   Q     I+N  + ++   +     +
Sbjct: 179  NV--KVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 236

Query: 1339 DSKSASLTIK--KVENTDAGIYKLRLENNCGHADVEMNVTILDK----PSPPGKPNILEI 1392
            D+   +L  K  K+   +  I+++R  N  G  D   +  ++ +    P  PG+P + ++
Sbjct: 237  DANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHPVIARFASLPDAPGRPEVTDV 296

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSY 1449
              S++++ W  P   G S ++ Y++E +   +  W  V     +  T+  +  L     Y
Sbjct: 297  TRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTRVNKDHVVYDTRLKVTGLMEGCDY 356

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
            +FR  AVN    S+ SE + +    + + I  P     + +++ E
Sbjct: 357  QFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPETLQIFDVSRE 401



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
            P PP    I ++    + + W  PE+ G S +  Y+VE +E+    W+ V  +  T T  
Sbjct: 387  PGPPETLQIFDVSREGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 446

Query: 1441 QN--LKTNSSYRFRAYAVN 1457
            ++  L     Y  R  AVN
Sbjct: 447  RSTGLIEGLEYEHRVTAVN 465



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 19/165 (11%)

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
           WL  G EI   +   +  +   H     L I NV       YT VA    G+A+    L 
Sbjct: 28  WLKNGVEIKSTDRCQMRTKKLTHS----LNIRNVHFGDAAEYTFVA----GKATSTATLY 79

Query: 727 IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780
           ++   +  P      E  ++++VR G S+ +   + G P P +TW K+N  +K       
Sbjct: 80  VEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 139

Query: 781 --KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             KS     S+++    ++ D G Y LKA+N  G  E S  + V+
Sbjct: 140 KIKSTDFATSLSVKDAIRI-DSGSYILKAKNVAG--EKSVTVNVK 181



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 9/160 (5%)

Query: 768 WCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
           W KN   +K+      ++   THS+ I +     D   YT  A    G A ++A + VE 
Sbjct: 28  WLKNGVEIKSTDRCQMRTKKLTHSLNI-RNVHFGDAAEYTFVA----GKATSTATLYVEV 82

Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
             E   +  L     + + V+   +I++   +   P P +TW ++N  +     I     
Sbjct: 83  EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENKIK 142

Query: 885 GENIELVITNVDS-EIDSGDYKCVASNSAGKSSHGARVTI 923
             +    ++  D+  IDSG Y   A N AG+ S    V +
Sbjct: 143 STDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKV 182



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 505 EQSMAPIF---VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
           E+ MAP F    E  R      G +++    ++G P P++TW +    +K   + +    
Sbjct: 83  EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENKIK 142

Query: 562 DDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             + AT L +++    D+G++   AKN AG  S T  + V
Sbjct: 143 STDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKV 182



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 42/169 (24%), Positives = 66/169 (39%), Gaps = 10/169 (5%)

Query: 1023 LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
            L+D   +EKD    EV +N E     W ++G  IK   ++     +     L IRN    
Sbjct: 2    LKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIK-STDRCQMRTKKLTHSLNIRNVHFG 60

Query: 1083 DEGEYSCILRDESCTAEVTVV---ELPP--EIITRLQNQKVNKGNKATFEIELTKGDAL- 1136
            D  EY+ +    + TA + V    E+ P  E+   L+   V +   +       KG    
Sbjct: 61   DAAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAP 120

Query: 1137 -VRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGN 1182
             V W KD   ++   +I+  I        L + D    D+G Y  +  N
Sbjct: 121  EVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSYILKAKN 169


>UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscurin.;
            n=2; Euteleostomi|Rep: Homolog of Homo sapiens "Obscurin.
            - Takifugu rubripes
          Length = 1954

 Score =  184 bits (447), Expect = 3e-44
 Identities = 147/595 (24%), Positives = 267/595 (44%), Gaps = 35/595 (5%)

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGES 751
            +L +TN+KK  EG Y+    N    AS+          K P Q+  +  L ++   +G+ 
Sbjct: 1299 ILTVTNMKKEDEGEYSCECRNDRTSASV--------SSKAPRQIRLMAKLNNVAAMEGKD 1350

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
             I    V      ++ W   + PV +     T+  G++H++TI      +D G  + +AE
Sbjct: 1351 AIFKCAVTPADA-SVRWFHKSVPVTSGLKYKTEHSGNSHTLTITSVTH-EDAGEISFEAE 1408

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
                     A + V+       EP +F  + + +TV+E+   KL   +++ P   + W +
Sbjct: 1409 GKS----CKANLQVQH------EPVMFKKKLENVTVEEQSEAKLEVELSK-PSDEVRWMK 1457

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            N+ +I P+  +    DG    LV+ +V ++ D G Y C    +    + G ++ ++++K+
Sbjct: 1458 NSVVIQPTGNLKICVDGAKQALVLKSV-TQADRGIYSC---ETLDDKTQG-KLNVEMKKI 1512

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
              +K L ++    E +TV LE + S   V   W  +  ++    +  I   G+       
Sbjct: 1513 QVIKGLTET-TAHETETVTLEVELSQADVDGSWTKDGIKVKSGGNSRITVLGKKHALTLS 1571

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D G +    +    S  L+V E      + + D  V EK+    E E++    +V
Sbjct: 1572 NLKMEDAGNVVFQAEGVRVSGRLIVLEPPAMISKPIMDISVPEKEKVTFECEVSRTNTEV 1631

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W +D   +KP K  +     G  R L I   S  D G Y C   D++ +A+++V     
Sbjct: 1632 KWFKDNVELKPGK-MFSIHSLGRKRTLVISKCSPEDAGTYICRTPDDNTSAKLSVHARDI 1690

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
             I+ +LQ+ +V +   ATF  E++  D   +WFK  ++++ S++I++  +G+   L    
Sbjct: 1691 RIVKKLQDVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFRS 1750

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
               +D GE       +  +A L V+E  + F  +L + I +  +   +L  ++   +  V
Sbjct: 1751 VTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKHR-GHLECQVSRASAKV 1809

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             WYK K+ I+   K+ + S+   R L I    E D+  YTC   D K++ KL VE
Sbjct: 1810 KWYKSKTEIKPGLKYEIQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVE 1864



 Score =  158 bits (383), Expect = 2e-36
 Identities = 182/871 (20%), Positives = 347/871 (39%), Gaps = 59/871 (6%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L C  V+ P+ ++ W   G+ +   + + +  +  +      L I  + K   G YT  A
Sbjct: 1083 LSCE-VSDPKVEVKWYKDGKLLTSTKAVHMESKGKIRE----LVIEKMDKKDAGEYTCEA 1137

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
                G   L   L++ T E    Q     ++  VR  E+++L+ ++      ++ W ++ 
Sbjct: 1138 ----GAEKLLFKLQM-TDEAVKFQKKAVNETCAVRASENIVLTTELTAE-NGSVKWFRDG 1191

Query: 773  ---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
               K  K    + DG + ++ I+K  + KD G Y+ +       A+      V+     +
Sbjct: 1192 VELKESKKYEMRKDGFSRTL-IVKSTETKDSGSYSCQT------AQDKLEFKVQVKGMLH 1244

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             EP            K  G+  +     +  VP          +      +    G    
Sbjct: 1245 TEPVHNTKIVGRCLPKTSGSDFISDAALKFVVPL-----KAATVELEGRYSVTTSGPQRI 1299

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            L +TN+  E D G+Y C   N    +S  ++    +  +  + ++       EGK  I +
Sbjct: 1300 LTVTNMKKE-DEGEYSCECRNDRTSASVSSKAPRQIRLMAKLNNVAAM----EGKDAIFK 1354

Query: 950  CQ-TSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007
            C  T    S +W+H    + SG+ ++     G             D G I    + +   
Sbjct: 1355 CAVTPADASVRWFHKSVPVTSGLKYKTE-HSGNSHTLTITSVTHEDAGEISFEAEGKSCK 1413

Query: 1008 TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK 1067
              L V+     F +KL++  V+E+  A LEVE++  + +V W ++  +I+P  N      
Sbjct: 1414 ANLQVQHEPVMFKKKLENVTVEEQSEAKLEVELSKPSDEVRWMKNSVVIQPTGN-LKICV 1472

Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127
             G  + L +++ +  D G YSC   D+    ++ V     ++I  L     ++    T E
Sbjct: 1473 DGAKQALVLKSVTQADRGIYSCETLDDKTQGKLNVEMKKIQVIKGLTETTAHETETVTLE 1532

Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
            +EL++ D    W KDG +++   + ++T+ GKK  L + +  ++DAG    +    + + 
Sbjct: 1533 VELSQADVDGSWTKDGIKVKSGGNSRITVLGKKHALTLSNLKMEDAGNVVFQAEGVRVSG 1592

Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247
             L V EP    +  + + I VP         E+     +V W+K    ++  + F++ S 
Sbjct: 1593 RLIVLEPPAMISKPIMD-ISVPEKEKVTFECEVSRTNTEVKWFKDNVELKPGKMFSIHSL 1651

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
             +KRTL+I KC+ +D   Y C   D  ++ KL V   +   +IV   ++  +      T 
Sbjct: 1652 GRKRTLVISKCSPEDAGTYICRTPDDNTSAKLSVHARDI--RIVKKLQDVEVMEKESATF 1709

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            + +  +    + +W   S  +K   + K   + ++  L  + V   D G  K   E  C 
Sbjct: 1710 VCEI-SHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFRSVTPEDMGEIKFTAEKACS 1768

Query: 1368 HADV---EMNVTIL----DKPSPPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVE 1418
             A +   E+ V  +    DK +       LE  +  +S  + W + +      + Y   E
Sbjct: 1769 SAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRASAKVKWYKSKTEIKPGLKY---E 1825

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNL-----KTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             Q  D    +++ N+ +             KT+        +++ V      E TE +  
Sbjct: 1826 IQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVEEQSISIVRELSPVEVTEPFAA 1885

Query: 1474 IKETKIQSPTVEKP---LKNITTEPNEDIEL 1501
            + E +I    V+ P   L  +  + + DIE+
Sbjct: 1886 VFEVEISMELVKPPVWTLNGVAVQESRDIEM 1916



 Score =  150 bits (363), Expect = 5e-34
 Identities = 141/568 (24%), Positives = 246/568 (43%), Gaps = 43/568 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  F KK +   V+E S+  LE  L + P  ++ W+     I P  N+ + ++       
Sbjct: 1422 PVMFKKKLENVTVEEQSEAKLEVEL-SKPSDEVRWMKNSVVIQPTGNLKICVDGAKQ--- 1477

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L + +V +   G Y+   ++ + +  L + +K         QVI+ L      + E+V
Sbjct: 1478 -ALVLKSVTQADRGIYSCETLDDKTQGKLNVEMK-------KIQVIKGLTETTAHETETV 1529

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSD---GDTHSITILKPKKVKDEGVYTLKAEN 809
             L  ++        +W K+   VK+         G  H++T L   K++D G    +AE 
Sbjct: 1530 TLEVEL-SQADVDGSWTKDGIKVKSGGNSRITVLGKKHALT-LSNLKMEDAGNVVFQAE- 1586

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYR 868
              G+  +  +I +E        PP  I++   +I+V EK  +     V+R     + W++
Sbjct: 1587 --GVRVSGRLIVLE--------PPAMISKPIMDISVPEKEKVTFECEVSRTNT-EVKWFK 1635

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            +N  + P +  + +  G    LVI+    E D+G Y C   +     +  A++++    +
Sbjct: 1636 DNVELKPGKMFSIHSLGRKRTLVISKCSPE-DAGTYICRTPDD----NTSAKLSVHARDI 1690

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
              VK LQ   E  E ++    C+ SH  V  +W+    ++   D+ ++ QEGR       
Sbjct: 1691 RIVKKLQ-DVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFR 1749

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                 D+G IK   +   +S  L VKE   +F++KL+D     K    LE +++  +A V
Sbjct: 1750 SVTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRASAKV 1809

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107
             W +    IKP   KY+ +     RKL I N    DE  Y+C   D+  + ++ V E   
Sbjct: 1810 KWYKSKTEIKPGL-KYEIQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVEEQSI 1868

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVR---WFKDGSEIQFSNHIQLTIDGKKQKLK 1164
             I+  L   +V +   A FE+E++    LV+   W  +G  +Q S  I++  +G   +L 
Sbjct: 1869 SIVRELSPVEVTEPFAAVFEVEISM--ELVKPPVWTLNGVAVQESRDIEMEKEGTLHRLT 1926

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
                     G      G SK +A L V+
Sbjct: 1927 FKKTKASMTGSVQFTAGKSKSSAQLAVK 1954



 Score =  143 bits (346), Expect = 5e-32
 Identities = 156/742 (21%), Positives = 301/742 (40%), Gaps = 49/742 (6%)

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
            +L C  VA P+ ++ W   G ++   + + VA +         L + +V+K   G Y+  
Sbjct: 706  VLSCD-VADPKTEVKWCKDGRQLASTKTVRVASKGKNRQ----LVLDSVEKKDAGEYSCE 760

Query: 712  AVNREGEASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
                +    L +  +++K+       V + +K+ +    + V LS +V  + +  + W K
Sbjct: 761  VGTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKATV---SQKVTLSCEV-SDSKTEVKWYK 816

Query: 771  NNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            + K +   KA+  +S G +  + I    K KD G Y   A    G  + +  I +E    
Sbjct: 817  DGKLLTSSKAIHAESKGRSRLLVIESVDK-KDAGEYMCDA----GTEKLAFKIHMEAARA 871

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT---WYRNNEIISPSETITQNFD 884
            E    P F+N+ + +  + K  +   A ++   V + T   WY++ + +SPS  +  +  
Sbjct: 872  EVQAKPAFLNK-EAVQREVKAVLSQKATLSCEVVDNATEVKWYKDGKQLSPSRAVQVDSK 930

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF--VKHLQKSYETEE 942
            G+  +LVI NV+ + D+G+Y C      G      +V +   K  F   + +QK  +   
Sbjct: 931  GKIRQLVICNVEKK-DAGEYTC----EVGTEKLAFKVQVAEIKSAFSNKESVQKDVKATV 985

Query: 943  GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             +   L C+ S      KWY + K ++      I  +G+            D G   C  
Sbjct: 986  SQKATLACEVSDAKTEVKWYKDGKLLTSTKTLHIESKGKSRQLVVDSVEKKDSGEYICEA 1045

Query: 1002 KDQETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058
              ++ +  L V E    F  K    ++ +      A L  E++    +V W +DG+++  
Sbjct: 1046 GTEKLAFRLHVAEAAVGFSNKESVKKEVKAALSQKATLSCEVSDPKVEVKWYKDGKLLTS 1105

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-- 1116
             K  +  E +G IR+L I      D GEY+C    E    ++ + +   +   +  N+  
Sbjct: 1106 TKAVH-MESKGKIRELVIEKMDKKDAGEYTCEAGAEKLLFKLQMTDEAVKFQKKAVNETC 1164

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
             V          ELT  +  V+WF+DG E++ S   ++  DG  + L +   +  D+G Y
Sbjct: 1165 AVRASENIVLTTELTAENGSVKWFRDGVELKESKKYEMRKDGFSRTLIVKSTETKDSGSY 1224

Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDETLDVTWYKKKS 1234
            SC+    K    + V+       +   + +   +P  + +     I D  L      K +
Sbjct: 1225 SCQTAQDKLEFKVQVKGMLHTEPVHNTKIVGRCLPKTSGSDF---ISDAALKFVVPLKAA 1281

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE 1294
             +E   ++++ +   +R L +    ++D+ EY+C   + +++  +  +      +++   
Sbjct: 1282 TVELEGRYSVTTSGPQRILTVTNMKKEDEGEYSCECRNDRTSASVSSKAPR-QIRLMAKL 1340

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPND---EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                   G D      ++    P D    W   S  +      K      S +LTI  V 
Sbjct: 1341 NNVAAMEGKDAI----FKCAVTPADASVRWFHKSVPVTSGLKYKTEHSGNSHTLTITSVT 1396

Query: 1352 NTDAGIYKLRLENNCGHADVEM 1373
            + DAG      E     A++++
Sbjct: 1397 HEDAGEISFEAEGKSCKANLQV 1418



 Score =  137 bits (331), Expect = 4e-30
 Identities = 135/500 (27%), Positives = 211/500 (42%), Gaps = 60/500 (12%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P+ +   K+  V  G+   LS  VVG+P P ITW K+   + +        DGD + +TI
Sbjct: 7    PRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGDVYRLTI 66

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
             +   ++D G Y  +A+N+ G A  +  + V  PTE     P+F+ +     V   G + 
Sbjct: 67   YE-LTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDVA 125

Query: 852  LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
             V RV  +P  +  W ++   +  S  +    D +   L I +V   +D G Y C A N+
Sbjct: 126  FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSV-RNLDGGTYTCRAQNT 184

Query: 912  AGKSSHGARVTIDV---------EKVTFVKHLQKS----------YETEE---------- 942
             G++   A +T+D          +  + + HLQK           Y +EE          
Sbjct: 185  VGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEESSITSSTVTS 244

Query: 943  ---GKTVILEC-QTSH-TVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGV 996
               GK   L C  T H      W  +   IS G  H     +              D G+
Sbjct: 245  VTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVIYEDQAENFILKILYCKQTDNGL 304

Query: 997  IKC---IVKDQETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
              C    +  Q  S +LV VKE    F RKLQD EV+EK  A+L  E+        W  +
Sbjct: 305  YTCNAGNMAGQTYSAVLVTVKEPQVPFRRKLQDVEVQEKKSAMLLCEVPLVATQTNWFME 364

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT-AEVTVVELPPEIIT 1111
             E    + +KY  E+ G +R+L I N + +D+G Y C +++ S T AE+TV         
Sbjct: 365  -ETRLEQSSKYYMEQEGTLRRLTIHNVTTNDDGVYICEMKEGSRTVAELTV--------- 414

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
                  VN  +   F +EL        W ++G +++  + I +    ++  L I DC  D
Sbjct: 415  ---RGMVN--DTVIFCVELEHPCVDAYWTRNGEKLKEDSRISIACSLRQYTLTIRDCQAD 469

Query: 1172 DAGEYSCEVGNSKCTAILTV 1191
            D+GE +   G+ K +    V
Sbjct: 470  DSGEVAFVAGDCKTSTRFAV 489



 Score =  130 bits (314), Expect = 4e-28
 Identities = 157/735 (21%), Positives = 276/735 (37%), Gaps = 45/735 (6%)

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
            +D ++ C  +  P  D  W   GE++  D  IS+A    +  Y   L I + +    G  
Sbjct: 419  NDTVIFCVELEHPCVDAYWTRNGEKLKEDSRISIACS--LRQY--TLTIRDCQADDSGEV 474

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL---SAQVVGNPRPT 765
              VA    G+        +    K PP    P+ ++   + ES I    S      P P 
Sbjct: 475  AFVA----GDCKTSTRFAVTAARKHPPD--PPVDAVTHNKTESSITIQWSPPDSDRPVPI 528

Query: 766  ITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
              +    + V  K     + G+T + T +      +E  Y  +        ++  +   E
Sbjct: 529  KGYIVERRKVGNKTWQRCNPGETITSTEITICSFTEEASYQFRISAMNDFGQSPYL---E 585

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
             P     EP   + +    +    G  +    V  + V S  W  N  ++          
Sbjct: 586  VPGSFYLEPLAEVTKGLINSTALAGR-EFSISVELSAVCSGFWSLNGRLLRSGADYLITR 644

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH-LQKSYETEE 942
                  L+I  V +++D    K V   S        +   + +   F K  +Q   +   
Sbjct: 645  SKSTHTLLIHCVTADMDGTVVKFVGGGSQSSCVLSVK---EAQSAFFKKESVQNDVKATV 701

Query: 943  GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             +  +L C  +      KW  + ++++      +  +G+            D G   C V
Sbjct: 702  SQKAVLSCDVADPKTEVKWCKDGRQLASTKTVRVASKGKNRQLVLDSVEKKDAGEYSCEV 761

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVEINSETADVVWERDGEII 1056
              ++    L V +   +     +D   KE    +     L  E++    +V W +DG+++
Sbjct: 762  GTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKATVSQKVTLSCEVSDSKTEVKWYKDGKLL 821

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV------VELPPEII 1110
               K  +  E +G  R L I +    D GEY C    E    ++ +      V+  P  +
Sbjct: 822  TSSKAIHA-ESKGRSRLLVIESVDKKDAGEYMCDAGTEKLAFKIHMEAARAEVQAKPAFL 880

Query: 1111 TRLQNQKVNKG---NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
             +   Q+  K     KAT   E+      V+W+KDG ++  S  +Q+   GK ++L I +
Sbjct: 881  NKEAVQREVKAVLSQKATLSCEVVDNATEVKWYKDGKQLSPSRAVQVDSKGKIRQLVICN 940

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETL 1225
             +  DAGEY+CEVG  K    + V E    F+ +  + + +    +  A L  E+ D   
Sbjct: 941  VEKKDAGEYTCEVGTEKLAFKVQVAEIKSAFSNKESVQKDVKATVSQKATLACEVSDAKT 1000

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EV 1283
            +V WYK   ++  T+   + S  K R L++    + D  EY C     K   +L V    
Sbjct: 1001 EVKWYKDGKLLTSTKTLHIESKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHVAEAA 1060

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            V F  K    ++E +       TL  +  + P+   +W  + K++   K        K  
Sbjct: 1061 VGFSNK-ESVKKEVKAALSQKATLSCEV-SDPKVEVKWYKDGKLLTSTKAVHMESKGKIR 1118

Query: 1344 SLTIKKVENTDAGIY 1358
             L I+K++  DAG Y
Sbjct: 1119 ELVIEKMDKKDAGEY 1133



 Score =  126 bits (305), Expect = 5e-27
 Identities = 274/1304 (21%), Positives = 485/1304 (37%), Gaps = 143/1304 (10%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+ + +      G      C V G P P ITW +    +     F+   D D V  L 
Sbjct: 7    PRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGD-VYRLT 65

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I E+  ED+G + C AKN  G A +   L V  P     +EM                  
Sbjct: 66   IYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALP-----TEMPHRA-------------- 106

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW----LFKGE----EIVPDENIS 681
                P F  KP +  V  G D+   CR+ A PE +  W     + GE    +IV D + S
Sbjct: 107  ----PVFVVKPASTRVGLGGDVAFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGS 162

Query: 682  -VAIES----DMHMYCSVLKITNVKKFQEGTYTVVA------VNREGEASLPIVLKIKTG 730
             + I+S    D   Y    + T  +       TV A      +  +  + L  + K K  
Sbjct: 163  TLKIQSVRNLDGGTYTCRAQNTVGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEE 222

Query: 731  EKEPPQVIEPLKSMI-------VRQGESVILSAQVVGNPRPTITWCKNNKPV----KALP 779
             K+   +    +S I       V  G+   LS  V G+P+P ITW K+   +    + + 
Sbjct: 223  MKKDISIYRSEESSITSSTVTSVTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVI 282

Query: 780  TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
             +   +   + IL  K+  D G+YT  A N  G   ++ ++TV+EP     + P F  + 
Sbjct: 283  YEDQAENFILKILYCKQT-DNGLYTCNAGNMAGQTYSAVLVTVKEP-----QVP-FRRKL 335

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            Q++ V+EK +  L+  V      +  W+     +  S       +G    L I NV +  
Sbjct: 336  QDVEVQEKKSAMLLCEVPLVATQT-NWFMEETRLEQSSKYYMEQEGTLRRLTIHNVTTN- 393

Query: 900  DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VST 958
            D G Y C       +   G+R   ++     V             TVI   +  H  V  
Sbjct: 394  DDGVYIC-------EMKEGSRTVAELTVRGMVND-----------TVIFCVELEHPCVDA 435

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018
             W  N +++       I    R            D G +  +  D +TST   V      
Sbjct: 436  YWTRNGEKLKEDSRISIACSLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFAVTAARKH 495

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK--NK-YDFEKRGH-IRKL 1074
                  D     K  + + ++ +   +D      G I++ +K  NK +     G  I   
Sbjct: 496  PPDPPVDAVTHNKTESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPGETITST 555

Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELP--------PEIITRLQNQKVNKGNKATF 1126
             I   S  +E  Y   +   +   +   +E+P         E+   L N     G + + 
Sbjct: 556  EITICSFTEEASYQFRISAMNDFGQSPYLEVPGSFYLEPLAEVTKGLINSTALAGREFSI 615

Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-SKC 1185
             +EL+   +   W  +G  ++      +T       L I+    D  G     VG  S+ 
Sbjct: 616  SVELSAVCSGF-WSLNGRLLRSGADYLITRSKSTHTLLIHCVTADMDGTVVKFVGGGSQS 674

Query: 1186 TAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
            + +L+V+E    F  +  +   +    +  A L+ ++ D   +V W K    +  T+   
Sbjct: 675  SCVLSVKEAQSAFFKKESVQNDVKATVSQKAVLSCDVADPKTEVKWCKDGRQLASTKTVR 734

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIK 1300
            + S  K R L++    + D  EY+C +   K   KL V  ++      +    ++E +  
Sbjct: 735  VASKGKNRQLVLDSVEKKDAGEYSCEVGTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKAT 794

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY-- 1358
                VTL  +     +   +W  + K++   K        +S  L I+ V+  DAG Y  
Sbjct: 795  VSQKVTLSCEVSD-SKTEVKWYKDGKLLTSSKAIHAESKGRSRLLVIESVDKKDAGEYMC 853

Query: 1359 -----KL--RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
                 KL  ++      A+V+     L+K +   +   +    ++++ C    E   N+T
Sbjct: 854  DAGTEKLAFKIHMEAARAEVQAKPAFLNKEAVQREVKAVLSQKATLS-C----EVVDNAT 908

Query: 1412 IIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             + +  + +++  +  + V +  K  Q  I N++   +  +      EV     +E   +
Sbjct: 909  EVKWYKDGKQLSPSRAVQVDSKGKIRQLVICNVEKKDAGEYTC----EV----GTEKLAF 960

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530
               + E K      E   K++    ++   L C      + +V WY+DGK L + K  + 
Sbjct: 961  KVQVAEIKSAFSNKESVQKDVKATVSQKATLACEVSDA-KTEVKWYKDGKLLTSTKTLHI 1019

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590
                                    + G  + +  + + +  V   + E +K++ K     
Sbjct: 1020 ESKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHVAEAAVGFSNKESVKKEVKAALSQ 1079

Query: 1591 LVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
              T   E   P  EV WYK+G  L + K  ++ +K K   + I+++ +  + +YT EA  
Sbjct: 1080 KATLSCEVSDPKVEVKWYKDGKLLTSTKAVHMESKGKIRELVIEKMDKKDAGEYTCEAGA 1139

Query: 1650 TAGTSSVEVT---LKVYDKP-------SKPEGPVIMREISRESVTIEWKPPLDDGG--LE 1697
                  +++T   +K   K           E  V+  E++ E+ +++W     DG    E
Sbjct: 1140 EKLLFKLQMTDEAVKFQKKAVNETCAVRASENIVLTTELTAENGSVKW---FRDGVELKE 1196

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
              KY + K        +K  +  +D  +Y  Q   +  E+  +V
Sbjct: 1197 SKKYEMRKDGFSRTLIVKSTET-KDSGSYSCQTAQDKLEFKVQV 1239



 Score =  124 bits (299), Expect = 3e-26
 Identities = 124/560 (22%), Positives = 219/560 (39%), Gaps = 36/560 (6%)

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            EG D + +C  V   +  + W  K   +            + H     L IT+V     G
Sbjct: 1347 EGKDAIFKCA-VTPADASVRWFHKSVPVTSGLKYKTEHSGNSH----TLTITSVTHEDAG 1401

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
              +  A  +  +A+L +       + EP    + L+++ V +     L  ++   P   +
Sbjct: 1402 EISFEAEGKSCKANLQV-------QHEPVMFKKKLENVTVEEQSEAKLEVEL-SKPSDEV 1453

Query: 767  TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             W KN+   +P   L    DG   ++ +LK     D G+Y+ +  + +    T   + VE
Sbjct: 1454 RWMKNSVVIQPTGNLKICVDGAKQAL-VLKSVTQADRGIYSCETLDDK----TQGKLNVE 1508

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                +       I    E T  E  T+ L   +++  V   +W ++   +          
Sbjct: 1509 MKKIQ------VIKGLTETTAHETETVTLEVELSQADVDG-SWTKDGIKVKSGGNSRITV 1561

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
             G+   L ++N+  E D+G+   V   + G    G  + +  E    +          E 
Sbjct: 1562 LGKKHALTLSNLKME-DAGN---VVFQAEGVRVSGRLIVL--EPPAMISKPIMDISVPEK 1615

Query: 944  KTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            + V  EC+ S T    KW+ +  E+       I   GR            D G   C   
Sbjct: 1616 EKVTFECEVSRTNTEVKWFKDNVELKPGKMFSIHSLGRKRTLVISKCSPEDAGTYICRTP 1675

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062
            D  TS  L V       ++KLQD EV EK+ A    EI+ +  D  W +    +K   N 
Sbjct: 1676 DDNTSAKLSVHARDIRIVKKLQDVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDN- 1734

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122
                + G    L  R+ +  D GE          +A++ V ELP + + +L+++     +
Sbjct: 1735 IKMRQEGRTYVLLFRSVTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKH 1794

Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +   E ++++  A V+W+K  +EI+     ++  +   +KL I + D  D   Y+C+  +
Sbjct: 1795 RGHLECQVSRASAKVKWYKSKTEIKPGLKYEIQSEDVYRKLTINNVDEADEDTYTCDATD 1854

Query: 1183 SKCTAILTVEEPSINFTLRL 1202
             K +  L VEE SI+    L
Sbjct: 1855 DKTSCKLLVEEQSISIVREL 1874



 Score =  118 bits (284), Expect = 2e-24
 Identities = 200/979 (20%), Positives = 358/979 (36%), Gaps = 68/979 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L + +V+K   G Y +     E  A    V +   G      V + +K+ +    +   L
Sbjct: 1028 LVVDSVEKKDSGEY-ICEAGTEKLAFRLHVAEAAVGFSNKESVKKEVKAAL---SQKATL 1083

Query: 755  SAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            S +V  +P+  + W K+ K     KA+  +S G    + I K  K KD G YT +A    
Sbjct: 1084 SCEV-SDPKVEVKWYKDGKLLTSTKAVHMESKGKIRELVIEKMDK-KDAGEYTCEAG--- 1138

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
              AE   +  ++   E        +N  +   V+    I L   +T     S+ W+R+  
Sbjct: 1139 --AE-KLLFKLQMTDEAVKFQKKAVN--ETCAVRASENIVLTTELTAEN-GSVKWFRDGV 1192

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +  S+      DG +  L++ + +++ DSG Y C  +    +     +  +  E V   
Sbjct: 1193 ELKESKKYEMRKDGFSRTLIVKSTETK-DSGSYSCQTAQDKLEFKVQVKGMLHTEPVHNT 1251

Query: 932  KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            K + +      G   I +      V  K      E+ G     +   G            
Sbjct: 1252 KIVGRCLPKTSGSDFISDAALKFVVPLK--AATVELEG--RYSVTTSGPQRILTVTNMKK 1307

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV 1048
             D G   C  ++  TS    V    P  IR   KL +    E   AI +  +    A V 
Sbjct: 1308 EDEGEYSCECRNDRTSAS--VSSKAPRQIRLMAKLNNVAAMEGKDAIFKCAVTPADASVR 1365

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W      +     KY  E  G+   L I + +  D GE S     +SC A + V   P  
Sbjct: 1366 WFHKSVPVTSGL-KYKTEHSGNSHTLTITSVTHEDAGEISFEAEGKSCKANLQVQHEPVM 1424

Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
               +L+N  V + ++A  E+EL+K    VRW K+   IQ + ++++ +DG KQ L +   
Sbjct: 1425 FKKKLENVTVEEQSEAKLEVELSKPSDEVRWMKNSVVIQPTGNLKICVDGAKQALVLKSV 1484

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228
               D G YSCE  + K    L VE   I     L E       T   L VE+    +D +
Sbjct: 1485 TQADRGIYSCETLDDKTQGKLNVEMKKIQVIKGLTETTAHETET-VTLEVELSQADVDGS 1543

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFP 1287
            W K    ++      +    KK  L +     +D      V+  A+      ++ V+E P
Sbjct: 1544 WTKDGIKVKSGGNSRITVLGKKHALTLSNLKMEDAGN---VVFQAEGVRVSGRLIVLEPP 1600

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
              I     +  +     VT   +         +W  ++  +K  K        +  +L I
Sbjct: 1601 AMISKPIMDISVPEKEKVTFECEVSR-TNTEVKWFKDNVELKPGKMFSIHSLGRKRTLVI 1659

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
             K    DAG Y  R  ++   A + ++   +          ++E +S++  +C       
Sbjct: 1660 SKCSPEDAGTYICRTPDDNTSAKLSVHARDIRIVKKLQDVEVMEKESATF-VC------- 1711

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
                     + + ++D  +W       K   +I+  +   +Y     +V   D+ +   T
Sbjct: 1712 --------EISHDDVD-CQWFKGSAKLKVSDNIKMRQEGRTYVLLFRSVTPEDMGEIKFT 1762

Query: 1468 TEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
             E      + K++   V+  K L++          L C        KV WY+   ++K  
Sbjct: 1763 AEKACSSAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRA-SAKVKWYKSKTEIKPG 1821

Query: 1526 KATYENRX-----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN-ED 1579
               YE +                    Y C A +D    +TSC + ++++ +  +     
Sbjct: 1822 -LKYEIQSEDVYRKLTINNVDEADEDTYTCDATDD----KTSCKLLVEEQSISIVRELSP 1876

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            ++        + V   +E + PP  +W  NG  ++  ++  +  +     +  K+ K S 
Sbjct: 1877 VEVTEPFAAVFEVEISMELVKPP--VWTLNGVAVQESRDIEMEKEGTLHRLTFKKTKASM 1934

Query: 1640 SSKYTIEASNTAGTSSVEV 1658
            +      A  +  ++ + V
Sbjct: 1935 TGSVQFTAGKSKSSAQLAV 1953



 Score =  104 bits (250), Expect = 2e-20
 Identities = 123/501 (24%), Positives = 195/501 (38%), Gaps = 58/501 (11%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            L G  P F  +PKA  V  G D  L C +V  P P I W     ++          + D+
Sbjct: 2    LFGGVPRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGDV 61

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744
            +     L I  +     G Y   A N  GEA   + LK+    +   + P  V++P  S 
Sbjct: 62   YR----LTIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKP-AST 116

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEG 801
             V  G  V    +V  +P     W K+ + +     +   SD D  ++ I   + + D G
Sbjct: 117  RVGLGGDVAFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSVRNL-DGG 175

Query: 802  VYTLKAENSEGIAETSAVITVE-------------------EPTEENAEPPLFINRFQE- 841
             YT +A+N+ G A  +A +TV+                   +  +E  +  + I R +E 
Sbjct: 176  TYTCRAQNTVGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEES 235

Query: 842  -------ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVIT 893
                    +V +    KL   VT +P P ITW ++   IS     +      EN  L I 
Sbjct: 236  SITSSTVTSVTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVIYEDQAENFILKIL 295

Query: 894  NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953
                + D+G Y C A N AG++     VT+   +V F + LQ   E +E K+ +L C+  
Sbjct: 296  YC-KQTDNGLYTCNAGNMAGQTYSAVLVTVKEPQVPFRRKLQ-DVEVQEKKSAMLLCEVP 353

Query: 954  HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012
               + T W+  +  +       + QEG             D GV  C +K+    +  V 
Sbjct: 354  LVATQTNWFMEETRLEQSSKYYMEQEGTLRRLTIHNVTTNDDGVYICEMKE---GSRTVA 410

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            + T+   +           D  I  VE+     D  W R+GE +K + ++          
Sbjct: 411  ELTVRGMV----------NDTVIFCVELEHPCVDAYWTRNGEKLK-EDSRISIACSLRQY 459

Query: 1073 KLYIRNTSVHDEGEYSCILRD 1093
             L IR+    D GE + +  D
Sbjct: 460  TLTIRDCQADDSGEVAFVAGD 480



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 80/350 (22%), Positives = 135/350 (38%), Gaps = 17/350 (4%)

Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           L D   Y    +  + E    + +     +E    AP+FV K        G  V F C+V
Sbjct: 71  LEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDVAFVCRV 130

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             +P     W +    +  S   ++  D D  +TL I+ V   D GT+TC A+N  G A 
Sbjct: 131 AAHPEANFEWEKDGRYLGESNRVKIVSDSDG-STLKIQSVRNLDGGTYTCRAQNTVGRAH 189

Query: 594 STTELIVEA-----PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
           +   L V+A      ++D  + +                I      + +       V +G
Sbjct: 190 AAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEESSITSSTVTS-VTDG 248

Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
               L C +   P+P I W   G  I  +    V  E     +  +LKI   K+   G Y
Sbjct: 249 KHAKLSCFVTGHPKPHITWRKDGTNI-SEGRRHVIYEDQAENF--ILKILYCKQTDNGLY 305

Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
           T  A N  G+    +++ +K  E + P     L+ + V++ +S +L  +V      T  +
Sbjct: 306 TCNAGNMAGQTYSAVLVTVK--EPQVP-FRRKLQDVEVQEKKSAMLLCEVPLVATQTNWF 362

Query: 769 CKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAE 815
            +  +  ++     + +G    +TI       D+GVY  +  E S  +AE
Sbjct: 363 MEETRLEQSSKYYMEQEGTLRRLTI-HNVTTNDDGVYICEMKEGSRTVAE 411



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 2/156 (1%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P  +  W +NG KL+ D   +I    +   + I++ +   S +    A +   ++   VT
Sbjct: 431  PCVDAYWTRNGEKLKEDSRISIACSLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFAVT 490

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
                  P  P   V   + +  S+TI+W PP  D  + +  Y +E+ +  N  W +    
Sbjct: 491  AARKHPPDPPVDAVTHNK-TESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPG 549

Query: 1720 DRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
            +    T   I    E   Y FR+ A N  G S  LE
Sbjct: 550  ETITSTEITICSFTEEASYQFRISAMNDFGQSPYLE 585



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 48/193 (24%), Positives = 83/193 (43%), Gaps = 17/193 (8%)

Query: 1016 IPEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
            +P F+ + + F V   KD  +    + S T  + WE+D ++      ++   + G + +L
Sbjct: 6    VPRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKD-KLKLTSGGRFKAVEDGDVYRL 64

Query: 1075 YIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEI-------ITRLQNQKVNKGNKA 1124
             I   ++ D G+Y C  ++   E+  A    V LP E+       + +  + +V  G   
Sbjct: 65   TIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDV 124

Query: 1125 TFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
             F   +    +A   W KDG  +  SN +++  D     LKI      D G Y+C     
Sbjct: 125  AFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSVRNLDGGTYTCRAQNT 184

Query: 1180 VGNSKCTAILTVE 1192
            VG +   A LTV+
Sbjct: 185  VGRAHAAAALTVD 197



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 3/87 (3%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-- 1922
            PP  P + V    T  S+T++W+ P+S+   PI  YI+E + V  K+W +    G ++  
Sbjct: 496  PPDPPVDAVTHNKTESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQR-CNPGETITS 554

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVS 1949
             E  I +  E+    FRISA N  G S
Sbjct: 555  TEITICSFTEEASYQFRISAMNDFGQS 581



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 66/299 (22%), Positives = 119/299 (39%), Gaps = 33/299 (11%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXX--- 1544
            K I    ++ + L+C      + +V WY+DGK L ++KA + E++               
Sbjct: 789  KEIKATVSQKVTLSCEVSD-SKTEVKWYKDGKLLTSSKAIHAESKGRSRLLVIESVDKKD 847

Query: 1545 XXXYKC------IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
               Y C      +AF  H E   +    +Q KP   ++ E ++++ K       T   E 
Sbjct: 848  AGEYMCDAGTEKLAFKIHMEAARA---EVQAKPAF-LNKEAVQREVKAVLSQKATLSCEV 903

Query: 1599 IP-PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            +    EV WYK+G +L   +   + +K K   + I  +++  + +YT E         V+
Sbjct: 904  VDNATEVKWYKDGKQLSPSRAVQVDSKGKIRQLVICNVEKKDAGEYTCEVGTEKLAFKVQ 963

Query: 1658 V-----------TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
            V           +++   K +  +   +  E+S     ++W     DG L  +   +   
Sbjct: 964  VAEIKSAFSNKESVQKDVKATVSQKATLACEVSDAKTEVKW---YKDGKLLTSTKTLHIE 1020

Query: 1707 EPDNNRWIKVADVD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
                +R + V  V+ +D   Y  +   E   +   V A+  VGFS   ES    +K AL
Sbjct: 1021 SKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHV-AEAAVGFSNK-ESVKKEVKAAL 1077



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 2/62 (3%)

Query: 522  PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            P+   V FEC+V      ++ WF+    +KP + F ++       TLVI +  PEDAGT+
Sbjct: 1613 PEKEKVTFECEVSR-TNTEVKWFKDNVELKPGKMFSIH-SLGRKRTLVISKCSPEDAGTY 1670

Query: 582  TC 583
             C
Sbjct: 1671 IC 1672



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 2/99 (2%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD-VNTL 2024
            P PP   +      S+I +  W  P+ D   P+ GY +  R V    W      + + + 
Sbjct: 497  PDPPVDAVTHNKTESSITI-QWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPGETITST 555

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            +  I   +E  +Y  RI A N+ G S  LE    F + P
Sbjct: 556  EITICSFTEEASYQFRISAMNDFGQSPYLEVPGSFYLEP 594


>UniRef50_A5PF15 Cluster: Novel protein similar to human obscurin,
            cytoskeletal calmodulin and titin-interacting RhoGEF;
            n=1; Danio rerio|Rep: Novel protein similar to human
            obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1602

 Score =  182 bits (444), Expect = 7e-44
 Identities = 158/591 (26%), Positives = 245/591 (41%), Gaps = 30/591 (5%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L I ++K    G Y   A    G  S    + +K     P +  + L +  V++GESV L
Sbjct: 1039 LAIRDIKDSDAGIYECNA----GSVSTKATVTVKA---IPAEFTKELLNQEVKEGESVTL 1091

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEG 812
              +    P     W K  + +K+          S   L    VK  D G YT    + + 
Sbjct: 1092 MCEY-SIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQK- 1149

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
               T A +TV      NA P  FI   +    +E  T+ L   +++  VP + W +  + 
Sbjct: 1150 ---TMATVTV------NAVPISFIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQT 1199

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            + P E          +ELVI N   E DSG Y CV  + + K    A + I  + +TF +
Sbjct: 1200 LCPGEKYQMRHIVTILELVIRNPVPE-DSGTYICVCEDQSTK----ADIKIRTQPITFKQ 1254

Query: 933  HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
             L+    TEEG +VIL C+ S   +  +W      +   +  +I Q G            
Sbjct: 1255 KLRNQM-TEEGSSVILHCEISKADIPVEWRKGNILLKSGEKYKIRQRGCILELKIFNLTQ 1313

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D G+  C  +  ETS  + V      F  KL++    E     L  E++     V W +
Sbjct: 1314 EDSGLYSCASETAETSANVTVSAQHVIFKEKLKNVVADEGKTITLHCEVSKTGVPVQWWK 1373

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
              E+++  + KY   +R    +L I      D G Y C+  D+   A + +V  P     
Sbjct: 1374 GDELLQFGE-KYKMRERDTSVELIISEAVAEDSGVYRCVCGDQKTKATIKIVGAPATFKQ 1432

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             L+NQ+  +G   T   EL+K DA V W K    I      Q+ ++GK  +L I +   +
Sbjct: 1433 DLKNQEALEGGSITLHCELSKSDAPVEWRKGDKLILPGPRFQMRLNGKTAELVISNVFPE 1492

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            DAG YSC  G+ K TA + V+   I F   L   + +   + A  T E+      V W K
Sbjct: 1493 DAGTYSCVTGDQKTTAEVKVKSLPITFKRELQNQVSIEGGS-AVFTCELSKPGAPVEWRK 1551

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             + +++   K+    + +   L I    E D   YTC   D++ST +L V+
Sbjct: 1552 GRVILKAGAKYHTTLEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAELTVQ 1602



 Score =  179 bits (435), Expect = 9e-43
 Identities = 170/728 (23%), Positives = 296/728 (40%), Gaps = 41/728 (5%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F+K+ K  + +E   ++LEC     P   + WL KG  ++   +  +  + D+ +    L
Sbjct: 806  FAKELKDVFAEEKGIVVLECE-TRQPATTVTWL-KGLMVLRSGHKYIMKKKDVLL---TL 860

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             I N++K     Y       +  A L +      G+K    +++ L+     +GE++I  
Sbjct: 861  TIFNLEKSDSAVYICDVGTMQSRALLTV-----QGQKVV--IVDELEDKECLEGETIIFR 913

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSE 811
             ++  +    + W  +   +            G  H++T  K    KD G    +A +  
Sbjct: 914  CRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTF-KQLARKDTGTIIFEAGDKR 972

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
              A  S ++    PT   A         +     E G++ L+ + T  P   I WY++  
Sbjct: 973  SYA--SLLVRERRPTITKA--------LENTEAIEGGSLMLLCK-TSKPC-HIVWYKDGC 1020

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
            +I  S     +  G    L I ++  + D+G Y+C    +AG  S  A VT+      F 
Sbjct: 1021 LIWNSSKYLVSRSGNEARLAIRDI-KDSDAGIYEC----NAGSVSTKATVTVKAIPAEFT 1075

Query: 932  KHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
            K L    E +EG++V L C+ S   +   W    + +   +   + Q             
Sbjct: 1076 KELLNQ-EVKEGESVTLMCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVK 1134

Query: 991  XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050
              D G   CI +DQ+T   + V      FI++L++ E +E     L  E++     V W 
Sbjct: 1135 PDDSGNYTCICRDQKTMATVTVNAVPISFIKELKNQETEEGKTMTLRCELSKAGVPVEWL 1194

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII 1110
            +  + + P + KY       I +L IRN    D G Y C+  D+S  A++ +   P    
Sbjct: 1195 KGKQTLCPGE-KYQMRHIVTILELVIRNPVPEDSGTYICVCEDQSTKADIKIRTQPITFK 1253

Query: 1111 TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
             +L+NQ   +G+      E++K D  V W K    ++     ++   G   +LKI++   
Sbjct: 1254 QKLRNQMTEEGSSVILHCEISKADIPVEWRKGNILLKSGEKYKIRQRGCILELKIFNLTQ 1313

Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230
            +D+G YSC    ++ +A +TV    + F  +L   +     T   L  E+    + V W+
Sbjct: 1314 EDSGLYSCASETAETSANVTVSAQHVIFKEKLKNVVADEGKTIT-LHCEVSKTGVPVQWW 1372

Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290
            K   +++  EK+ +        LII +   +D   Y CV  D K  TK  +++V  P   
Sbjct: 1373 KGDELLQFGEKYKMRERDTSVELIISEAVAEDSGVYRCVCGDQK--TKATIKIVGAPATF 1430

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
                +      G  +TL  +      P  EW    K+I      +  ++ K+A L I  V
Sbjct: 1431 KQDLKNQEALEGGSITLHCELSKSDAPV-EWRKGDKLILPGPRFQMRLNGKTAELVISNV 1489

Query: 1351 ENTDAGIY 1358
               DAG Y
Sbjct: 1490 FPEDAGTY 1497



 Score =  178 bits (434), Expect = 1e-42
 Identities = 153/569 (26%), Positives = 247/569 (43%), Gaps = 38/569 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++ IP  F+K+   Q V EG  + L C   +IP     W  KG E +     S       
Sbjct: 1067 VKAIPAEFTKELLNQEVKEGESVTLMCEY-SIPGIQFVWR-KGPETLKS---SEKYHMRQ 1121

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
               C  L I NVK    G YT +  +++  A++ +          P   I+ LK+    +
Sbjct: 1122 RKSCISLAIHNVKPDDSGNYTCICRDQKTMATVTV-------NAVPISFIKELKNQETEE 1174

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL----KPKKVKDEGVYT 804
            G+++ L  ++     P + W K  + +   P +     H +TIL    +    +D G Y 
Sbjct: 1175 GKTMTLRCELSKAGVP-VEWLKGKQTL--CPGEKYQMRHIVTILELVIRNPVPEDSGTYI 1231

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
               E+      T A I +        +P  F  + +    +E  ++ L   +++  +P +
Sbjct: 1232 CVCEDQS----TKADIKIR------TQPITFKQKLRNQMTEEGSSVILHCEISKADIP-V 1280

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W + N ++   E       G  +EL I N+  E DSG Y C AS +A  S   A VT+ 
Sbjct: 1281 EWRKGNILLKSGEKYKIRQRGCILELKIFNLTQE-DSGLYSC-ASETAETS---ANVTVS 1335

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983
             + V F + L K+   +EGKT+ L C+ S T V  +W+   + +   +  ++ +      
Sbjct: 1336 AQHVIFKEKL-KNVVADEGKTITLHCEVSKTGVPVQWWKGDELLQFGEKYKMRERDTSVE 1394

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                     D GV +C+  DQ+T   + +      F + L++ E  E     L  E++  
Sbjct: 1395 LIISEAVAEDSGVYRCVCGDQKTKATIKIVGAPATFKQDLKNQEALEGGSITLHCELSKS 1454

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
             A V W +  ++I P   ++     G   +L I N    D G YSC+  D+  TAEV V 
Sbjct: 1455 DAPVEWRKGDKLILPGP-RFQMRLNGKTAELVISNVFPEDAGTYSCVTGDQKTTAEVKVK 1513

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
             LP      LQNQ   +G  A F  EL+K  A V W K    ++       T++G+  KL
Sbjct: 1514 SLPITFKRELQNQVSIEGGSAVFTCELSKPGAPVEWRKGRVILKAGAKYHTTLEGRLTKL 1573

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             I +    DAG Y+C+  +S+ TA LTV+
Sbjct: 1574 AINNLVEGDAGNYTCKTKDSQSTAELTVQ 1602



 Score =  172 bits (419), Expect = 8e-41
 Identities = 245/1047 (23%), Positives = 402/1047 (38%), Gaps = 94/1047 (8%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            T  K+ +   V EG     EC L      +  W   G+ IV +  I VA E   +     
Sbjct: 626  TIVKRIRTATVLEGESCSFECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKY----T 681

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            + I  V     G   V ++    E S   +L +K   ++P +V   + ++    GE   L
Sbjct: 682  MSIEEVMTSDAGE-VVFSIK---ELSCRTMLFVK---EKPVRVFRDMLNVKATPGEDPEL 734

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            S ++   P  T+ W KN + ++  P    +  D     I+    + D G Y  +A+   G
Sbjct: 735  SCEIT-KPDATVKWLKNGRQIRVSPKYEITQKDYLVKLIIHNAAIMDSGEYCCEAD---G 790

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            IA T A + V +          F    +++  +EKG + L    TR P  ++TW +   +
Sbjct: 791  IA-TRARLDVRDLQHA------FAKELKDVFAEEKGIVVLECE-TRQPATTVTWLKGLMV 842

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +              + L I N++   DS  Y C      G     A +T+  +KV  V 
Sbjct: 843  LRSGHKYIMKKKDVLLTLTIFNLEKS-DSAVYIC----DVGTMQSRALLTVQGQKVVIVD 897

Query: 933  HLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXX 989
             L+   E  EG+T+I  C+   S     KWY ++  +   D  EI+   G          
Sbjct: 898  ELEDK-ECLEGETIIFRCRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTFKQL 956

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
               D G I     D+ +   L+V+E  P   + L++ E  E    +L  +  S+   +VW
Sbjct: 957  ARKDTGTIIFEAGDKRSYASLLVRERRPTITKALENTEAIEGGSLMLLCK-TSKPCHIVW 1015

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             +DG +I    +KY   + G+  +L IR+    D G Y C     S  A VTV  +P E 
Sbjct: 1016 YKDGCLIW-NSSKYLVSRSGNEARLAIRDIKDSDAGIYECNAGSVSTKATVTVKAIPAEF 1074

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
               L NQ+V +G   T   E +       W K    ++ S    +        L I++  
Sbjct: 1075 TKELLNQEVKEGESVTLMCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVK 1134

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
             DD+G Y+C   + K  A +TV    I+F   L         T   L  E+    + V W
Sbjct: 1135 PDDSGNYTCICRDQKTMATVTVNAVPISFIKELKNQETEEGKT-MTLRCELSKAGVPVEW 1193

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP 1287
             K K  +   EK+ +   V    L+IR    +D   Y CV  D   K+  K++ + + F 
Sbjct: 1194 LKGKQTLCPGEKYQMRHIVTILELVIRNPVPEDSGTYICVCEDQSTKADIKIRTQPITFK 1253

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
             K+    R    + GS V L  +      P  EW   + ++K  +  K         L I
Sbjct: 1254 QKL----RNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKIRQRGCILELKI 1308

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
              +   D+G+Y    E     A+   NVT+          +++       N+  DE    
Sbjct: 1309 FNLTQEDSGLYSCASET----AETSANVTV-------SAQHVI-FKEKLKNVVADE---- 1352

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDA-S 1465
            G +  ++  V    +    W             + L+    Y+ R    + E+ IS+A +
Sbjct: 1353 GKTITLHCEVSKTGVPVQWW----------KGDELLQFGEKYKMRERDTSVELIISEAVA 1402

Query: 1466 ETTEYYKVI---KETK-----IQSP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            E +  Y+ +   ++TK     + +P T ++ LKN        I L C       P V W 
Sbjct: 1403 EDSGVYRCVCGDQKTKATIKIVGAPATFKQDLKNQEALEGGSITLHCELSKSDAP-VEW- 1460

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXX-----XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            R G KL      ++ R                    Y C+     G+ +T+  V ++  P
Sbjct: 1461 RKGDKLILPGPRFQMRLNGKTAELVISNVFPEDAGTYSCVT----GDQKTTAEVKVKSLP 1516

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             IT   E   Q    G   + T  +   P   V W K    L+   +Y+ T + + + + 
Sbjct: 1517 -ITFKRELQNQVSIEGGSAVFTCELSK-PGAPVEWRKGRVILKAGAKYHTTLEGRLTKLA 1574

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEV 1658
            I  L    +  YT +  ++  T+ + V
Sbjct: 1575 INNLVEGDAGNYTCKTKDSQSTAELTV 1601



 Score =  169 bits (412), Expect = 5e-40
 Identities = 229/1062 (21%), Positives = 412/1062 (38%), Gaps = 92/1062 (8%)

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
            LLEC+ V+     + W  + +EIVP+    V  E    +Y  ++ I +V    E T+   
Sbjct: 198  LLECQ-VSRANAVVEWFKRNQEIVPNRKYQVVSEG---VYRQLI-IEDVGSSDEDTFICD 252

Query: 712  AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
            AV+      L +       E++   ++  L S+ V + +      +          W  N
Sbjct: 253  AVDERTSCQLFV-------EEQAISILRGLSSVEVMEPKEACFKVETSIKLERAPKWTLN 305

Query: 772  NK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
             +   P   +  +  G +H +        + +       + + G +++ A +TV      
Sbjct: 306  GQILFPCPDIRIERQGTSHRLIF-----TQTDSSMCGTVQFTSGKSKSEAQLTV------ 354

Query: 829  NAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
              E PL + +   ++  KE G++ L      +P   + W++    +  S   T   +   
Sbjct: 355  -TERPLIVKQPISDVEEKENGSVTLSCEFCPSP-RVVRWFKGRTPLFASNKYTIKREKNR 412

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
            +E+ I  V +  DSG+Y+CVA    G  + G +V + V+K+  ++HL++  E EE  T +
Sbjct: 413  VEMTILGVKAA-DSGEYRCVAG---GSETRG-KVNVKVKKLKIIRHLEQ-VEAEEDGTAV 466

Query: 948  LECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
              C+ +H + S +W  N K +   +H   IQ                   I     D   
Sbjct: 467  FCCELNHESPSVQWLLNDKVLH-TNHINKIQNSGKVYSLILKRLTPQESRITFKSLDISE 525

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFE 1066
            S  L V+E    F R L+D   +E+   +L+ E++  +   VW +DGEI+   + KY+  
Sbjct: 526  SAFLRVREKPAVFFRSLEDVAGEERGEILLQCEVSKPSVTPVWRKDGEILNSTE-KYEIL 584

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF 1126
              G    L I      D GEYSC +      A+VTV +L   I+ R++   V +G   +F
Sbjct: 585  HVGKSLTLKIHKLIKEDGGEYSCDIGCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSF 644

Query: 1127 EIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
            E  L+        W  +G  I  +  I +  +G+K  + I +    DAGE    +    C
Sbjct: 645  ECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKYTMSIEEVMTSDAGEVVFSIKELSC 704

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245
              +L V+E  +     +      P   D  L+ EI      V W K    I  + K+ + 
Sbjct: 705  RTMLFVKEKPVRVFRDMLNVKATPGE-DPELSCEITKPDATVKWLKNGRQIRVSPKYEIT 763

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYEREYRIKRGS 1303
                   LII      D  EY C      +  +L V  ++  F  ++ D   E   ++G 
Sbjct: 764  QKDYLVKLIIHNAAIMDSGEYCCEADGIATRARLDVRDLQHAFAKELKDVFAE---EKG- 819

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
             + +L      P     W+    +++              +LTI  +E +D+ +Y     
Sbjct: 820  -IVVLECETRQPATTVTWLKGLMVLRSGHKYIMKKKDVLLTLTIFNLEKSDSAVYIC--- 875

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
             + G       +T+  +        ++ +D      C +     G + I    +   +  
Sbjct: 876  -DVGTMQSRALLTVQGQ-------KVVIVDELEDKECLE-----GETIIFRCRICPSDYT 922

Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYR---FRAYAVNEVD--ISDASETTEYYKVIKETK 1478
              +W   + +  T    + +     Y    F+  A  +    I +A +   Y  ++   +
Sbjct: 923  DVKWYLDETLLYTNDLNEIMMIPGGYHTLTFKQLARKDTGTIIFEAGDKRSYASLL--VR 980

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXX 1534
             + PT+ K L+N  TE  E   L  +        + WY+DG       K   +   N   
Sbjct: 981  ERRPTITKALEN--TEAIEGGSLMLLCKTSKPCHIVWYKDGCLIWNSSKYLVSRSGNEAR 1038

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y+C A    G V T   V ++  P    + E + Q+ K G+   VT 
Sbjct: 1039 LAIRDIKDSDAGIYECNA----GSVSTKATVTVKAIPA-EFTKELLNQEVKEGES--VTL 1091

Query: 1595 VIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            + E  IP  + +W K    L++ ++Y++  ++    + I  +K   S  YT    +    
Sbjct: 1092 MCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQKTM 1151

Query: 1654 SSVEVT------LKVYDKPSKPEGPVI-MR-EISRESVTIEW 1687
            ++V V       +K        EG  + +R E+S+  V +EW
Sbjct: 1152 ATVTVNAVPISFIKELKNQETEEGKTMTLRCELSKAGVPVEW 1193



 Score =  136 bits (328), Expect = 8e-30
 Identities = 167/776 (21%), Positives = 294/776 (37%), Gaps = 73/776 (9%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            FV  LR K          ECQV       + WF++   I P++ +Q+   +     L+I 
Sbjct: 182  FVRPLRVKIAMYKHRALLECQVSR-ANAVVEWFKRNQEIVPNRKYQVV-SEGVYRQLIIE 239

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
            +V   D  TF C A +      ++ +L VE        E  +              IL G
Sbjct: 240  DVGSSDEDTFICDAVDER----TSCQLFVE--------EQAIS-------------ILRG 274

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +      +PK       + I LE      P+    W   G+ + P  +I +  +   H  
Sbjct: 275  LSSVEVMEPKEACFKVETSIKLE----RAPK----WTLNGQILFPCPDIRIERQGTSHR- 325

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L  T       GT    +   + EA L +        + P  V +P+  +  ++  S
Sbjct: 326  ---LIFTQTDSSMCGTVQFTSGKSKSEAQLTVT-------ERPLIVKQPISDVEEKENGS 375

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V LS +   +PR  + W K   P+ A      K + +   +TIL  K   D G Y   A 
Sbjct: 376  VTLSCEFCPSPR-VVRWFKGRTPLFASNKYTIKREKNRVEMTILGVKAA-DSGEYRCVA- 432

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
               G +ET   + V+       +    I   +++  +E GT      +     PS+ W  
Sbjct: 433  ---GGSETRGKVNVK------VKKLKIIRHLEQVEAEEDGTAVFCCELNHES-PSVQWLL 482

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            N++++  +        G+   L++  +  +     +K +        S  A + +  +  
Sbjct: 483  NDKVLHTNHINKIQNSGKVYSLILKRLTPQESRITFKSL------DISESAFLRVREKPA 536

Query: 929  TFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             F + L+     E G+ ++L+C+ S  +V+  W  + + ++  +  EI+  G+       
Sbjct: 537  VFFRSLEDVAGEERGE-ILLQCEVSKPSVTPVWRKDGEILNSTEKYEILHVGKSLTLKIH 595

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD- 1046
                 D G   C +   +T   + V++     +++++   V E +    E  ++ E  D 
Sbjct: 596  KLIKEDGGEYSCDIGCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSFECVLSHEIIDE 655

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106
              W  +G++I   + +      G    + I      D GE    +++ SC   + V E P
Sbjct: 656  AFWNMNGQLIVSNR-RIIVANEGRKYTMSIEEVMTSDAGEVVFSIKELSCRTMLFVKEKP 714

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
              +   + N K   G       E+TK DA V+W K+G +I+ S   ++T      KL I+
Sbjct: 715  VRVFRDMLNVKATPGEDPELSCEITKPDATVKWLKNGRQIRVSPKYEITQKDYLVKLIIH 774

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
            +  + D+GEY CE       A L V +    F   L + +         L  E       
Sbjct: 775  NAAIMDSGEYCCEADGIATRARLDVRDLQHAFAKELKD-VFAEEKGIVVLECETRQPATT 833

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            VTW K   V+    K+ +       TL I    + D   Y C +   +S   L V+
Sbjct: 834  VTWLKGLMVLRSGHKYIMKKKDVLLTLTIFNLEKSDSAVYICDVGTMQSRALLTVQ 889



 Score =  120 bits (290), Expect = 3e-25
 Identities = 116/494 (23%), Positives = 200/494 (40%), Gaps = 13/494 (2%)

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W R+   I           G+N  L +T V +  D G    + S  A      A +T+  
Sbjct: 34   WTRDGVPIKSRPVCRIAMQGKNHTLTLTRV-TLADMG----IISFKAEGIETSAMLTVTA 88

Query: 926  EKVTFVKHLQKSYETE-EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984
              +  VK LQ    TE E  T I E      V  KWY +   +   D+ +I  EG+    
Sbjct: 89   RDIKIVKALQNVSVTERESLTFICEVNWED-VDGKWYKDNSRLKAGDNIKIRCEGKIHSL 147

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D G I+   +   ++ ML VKE    F+R L+      K  A+LE +++   
Sbjct: 148  TYKSVRSEDAGEIRFTAERVSSTAMLRVKELPVHFVRPLRVKIAMYKHRALLECQVSRAN 207

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            A V W +  + I P + KY     G  R+L I +    DE  + C   DE  + ++ V E
Sbjct: 208  AVVEWFKRNQEIVPNR-KYQVVSEGVYRQLIIEDVGSSDEDTFICDAVDERTSCQLFVEE 266

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
                I+  L + +V +  +A F++E + K +   +W  +G  +     I++   G   +L
Sbjct: 267  QAISILRGLSSVEVMEPKEACFKVETSIKLERAPKWTLNGQILFPCPDIRIERQGTSHRL 326

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
                 D    G      G SK  A LTV E  +     + + +    N    L+ E    
Sbjct: 327  IFTQTDSSMCGTVQFTSGKSKSEAQLTVTERPLIVKQPISD-VEEKENGSVTLSCEFCPS 385

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
               V W+K ++ +  + K+T+  +  +  + I      D  EY CV   +++  K+ V+V
Sbjct: 386  PRVVRWFKGRTPLFASNKYTIKREKNRVEMTILGVKAADSGEYRCVAGGSETRGKVNVKV 445

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             +   KI+ +  +   +         +      P+ +W++N K++      K     K  
Sbjct: 446  KKL--KIIRHLEQVEAEEDGTAVFCCELN-HESPSVQWLLNDKVLHTNHINKIQNSGKVY 502

Query: 1344 SLTIKKVENTDAGI 1357
            SL +K++   ++ I
Sbjct: 503  SLILKRLTPQESRI 516



 Score =  104 bits (250), Expect = 2e-20
 Identities = 135/631 (21%), Positives = 263/631 (41%), Gaps = 39/631 (6%)

Query: 736  QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITIL 792
            ++++ L+++ V + ES+    +V         W K+N  +KA   +  + +G  HS+T  
Sbjct: 92   KIVKALQNVSVTERESLTFICEVNWEDVDG-KWYKDNSRLKAGDNIKIRCEGKIHSLTY- 149

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            K  + +D G     AE       ++A++ V+E       P  F+   +      K    L
Sbjct: 150  KSVRSEDAGEIRFTAER----VSSTAMLRVKEL------PVHFVRPLRVKIAMYKHRALL 199

Query: 853  VARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
              +V+R N V  + W++ N+ I P+       +G   +L+I +V S  D   + C A + 
Sbjct: 200  ECQVSRANAV--VEWFKRNQEIVPNRKYQVVSEGVYRQLIIEDVGSS-DEDTFICDAVDE 256

Query: 912  AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISG 969
              ++S   ++ ++ + ++ ++ L  S E  E K    + +TS  +  + KW  N + +  
Sbjct: 257  --RTS--CQLFVEEQAISILRGL-SSVEVMEPKEACFKVETSIKLERAPKWTLNGQILFP 311

Query: 970  MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK-LQDFEV 1028
                 I ++G               G ++      ++   L V E  P  +++ + D E 
Sbjct: 312  CPDIRIERQGTSHRLIFTQTDSSMCGTVQFTSGKSKSEAQLTVTER-PLIVKQPISDVEE 370

Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            KE     L  E       V W + G       NKY  ++  +  ++ I      D GEY 
Sbjct: 371  KENGSVTLSCEFCPSPRVVRWFK-GRTPLFASNKYTIKREKNRVEMTILGVKAADSGEYR 429

Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
            C+        +V V     +II  L+  +  +   A F  EL      V+W  +  ++  
Sbjct: 430  CVAGGSETRGKVNVKVKKLKIIRHLEQVEAEEDGTAVFCCELNHESPSVQWLLN-DKVLH 488

Query: 1149 SNHI-QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
            +NHI ++   GK   L +      ++      +  S+   +   E+P++ F  R  E + 
Sbjct: 489  TNHINKIQNSGKVYSLILKRLTPQESRITFKSLDISESAFLRVREKPAVFF--RSLEDVA 546

Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
                 +  L  E+   ++   W K   ++  TEK+ ++   K  TL I K  ++D  EY+
Sbjct: 547  GEERGEILLQCEVSKPSVTPVWRKDGEILNSTEKYEILHVGKSLTLKIHKLIKEDGGEYS 606

Query: 1268 CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNS 1325
            C +    S TK KV V +    IV   R   +  G   +   ++ ++   +    W +N 
Sbjct: 607  CDI--GCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSFECVLSHEIIDEA--FWNMNG 662

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
            ++I   +    + + +  +++I++V  +DAG
Sbjct: 663  QLIVSNRRIIVANEGRKYTMSIEEVMTSDAG 693



 Score =  104 bits (249), Expect = 3e-20
 Identities = 160/781 (20%), Positives = 301/781 (38%), Gaps = 54/781 (6%)

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            ++  VK L+ +   E+ +    E   SH  V  +W  +   I       I  +G+     
Sbjct: 1    RIQLVKGLEDATLCEK-EACTFEVVLSHAYVRGQWTRDGVPIKSRPVCRIAMQGKNHTLT 59

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D+G+I    +  ETS ML V     + ++ LQ+  V E++      E+N E  
Sbjct: 60   LTRVTLADMGIISFKAEGIETSAMLTVTARDIKIVKALQNVSVTERESLTFICEVNWEDV 119

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105
            D  W +D   +K   N       G I  L  ++    D GE        S TA + V EL
Sbjct: 120  DGKWYKDNSRLKAGDN-IKIRCEGKIHSLTYKSVRSEDAGEIRFTAERVSSTAMLRVKEL 178

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P   +  L+ +     ++A  E ++++ +A+V WFK   EI  +   Q+  +G  ++L I
Sbjct: 179  PVHFVRPLRVKIAMYKHRALLECQVSRANAVVEWFKRNQEIVPNRKYQVVSEGVYRQLII 238

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF-ILVPANTDAYLTVEIPDET 1224
             D    D   + C+  + + +  L VEE +I+    L    ++ P      +   I  E 
Sbjct: 239  EDVGSSDEDTFICDAVDERTSCQLFVEEQAISILRGLSSVEVMEPKEACFKVETSIKLER 298

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
                W     ++       +        LI  + T+   C  T      KS ++ ++ V 
Sbjct: 299  AP-KWTLNGQILFPCPDIRIERQGTSHRLIFTQ-TDSSMCG-TVQFTSGKSKSEAQLTVT 355

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            E P  +     +   K    VTL  ++   P+    +   + +    K+T    +     
Sbjct: 356  ERPLIVKQPISDVEEKENGSVTLSCEFCPSPRVVRWFKGRTPLFASNKYTIKR-EKNRVE 414

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            +TI  V+  D+G Y+     +     V + V  L K     +    E D +++  C    
Sbjct: 415  MTILGVKAADSGEYRCVAGGSETRGKVNVKVKKL-KIIRHLEQVEAEEDGTAVFCC---- 469

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
            E    S  + +++  + + T     ++N  K  + I    T    R        +DIS++
Sbjct: 470  ELNHESPSVQWLLNDKVLHTNHINKIQNSGKVYSLILKRLTPQESRI---TFKSLDISES 526

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT--WYRDGKKL 1522
            +    + +V ++  +      + L+++  E   +I L C    V +P VT  W +DG+ L
Sbjct: 527  A----FLRVREKPAV----FFRSLEDVAGEERGEILLQC---EVSKPSVTPVWRKDGEIL 575

Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIK 1581
             + +  YE                 +K I   D GE   SC +G  Q K  +T+ +  I 
Sbjct: 576  NSTE-KYE-----ILHVGKSLTLKIHKLIK-EDGGEY--SCDIGCSQTKAKVTVRDLHIT 626

Query: 1582 QKHKV-------GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
               ++       G+      V+      E  W  NG  + +++   +  + +   + I+E
Sbjct: 627  IVKRIRTATVLEGESCSFECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKYTMSIEE 686

Query: 1635 LKRSHSSKYTIEASNTAGTSSV---EVTLKVYD-----KPSKPEGPVIMREISRESVTIE 1686
            +  S + +        +  + +   E  ++V+      K +  E P +  EI++   T++
Sbjct: 687  VMTSDAGEVVFSIKELSCRTMLFVKEKPVRVFRDMLNVKATPGEDPELSCEITKPDATVK 746

Query: 1687 W 1687
            W
Sbjct: 747  W 747



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F + L+ +   +G ++   C++     P + W +   +I P   FQM  +    A LVI 
Sbjct: 1430 FKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNG-KTAELVIS 1487

Query: 572  EVFPEDAGTFTCV 584
             VFPEDAGT++CV
Sbjct: 1488 NVFPEDAGTYSCV 1500



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 2/76 (2%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F+++L+ + T +G T+   C++     P + W +    + P + +QM +    +  LVIR
Sbjct: 1163 FIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMRHIV-TILELVIR 1220

Query: 572  EVFPEDAGTFTCVAKN 587
               PED+GT+ CV ++
Sbjct: 1221 NPVPEDSGTYICVCED 1236



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 497  VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            V  K T   +++   F ++L  +   +G +V   C+    P  Q  W +    +K S+ +
Sbjct: 1059 VSTKATVTVKAIPAEFTKELLNQEVKEGESVTLMCEYS-IPGIQFVWRKGPETLKSSEKY 1117

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
             M      ++ L I  V P+D+G +TC+ ++    A+ T   +
Sbjct: 1118 HMRQRKSCIS-LAIHNVKPDDSGNYTCICRDQKTMATVTVNAV 1159



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            IF EKL+     +G T+   C+V     P + W++   +++  + ++M   D +V  L+I
Sbjct: 1340 IFKEKLKNVVADEGKTITLHCEVSKTGVP-VQWWKGDELLQFGEKYKMRERDTSVE-LII 1397

Query: 571  REVFPEDAGTFTCV 584
             E   ED+G + CV
Sbjct: 1398 SEAVAEDSGVYRCV 1411



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            F +KLR + T +GS+V   C++     P + W +   ++K  + +++      +  L I 
Sbjct: 1252 FKQKLRNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKI-RQRGCILELKIF 1309

Query: 572  EVFPEDAGTFTCVAKNAAGFASST 595
             +  ED+G ++C ++ A   A+ T
Sbjct: 1310 NLTQEDSGLYSCASETAETSANVT 1333


>UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome shotgun
            sequence; n=3; Tetraodontidae|Rep: Chromosome 5
            SCAF14581, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1276

 Score =  182 bits (443), Expect = 1e-43
 Identities = 133/480 (27%), Positives = 223/480 (46%), Gaps = 23/480 (4%)

Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            F+RKL   ++V +     L VE+ +  ADV W ++G+   P   +Y FE  G++R L I 
Sbjct: 341  FLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPT-GRYIFESVGNMRYLTIN 399

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
            N S+ D+  Y C++ +E  T+E+ V E P  I+  L++Q V KG++   E E+++  A V
Sbjct: 400  NCSLADDAAYCCVVGEEKSTSELFVKEPPVLIVKNLEDQMVMKGDRVELECEVSEEGANV 459

Query: 1138 RWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
            +W KDG E+      +     DG K  L I D   +D G Y  +    +  A L V+E  
Sbjct: 460  KWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVKTNGGESMAELLVQEKE 519

Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255
            +     + + + V A   A    E+ DE +  TWYK  + ++   +  +    +   L I
Sbjct: 520  LEIYQSIAD-LTVKAKDQALFKCEVSDENVRGTWYKNGAEVKPDARINITHIGRIHKLTI 578

Query: 1256 RKCTEDDQCEYTCV------LLDAK-STTKLKVEVV--EFPPKI-VD-----YEREYRIK 1300
                  D+ +YT V       L AK +  ++K++ V  + PPKI +D      E    + 
Sbjct: 579  DDVKPGDEGDYTFVPDGYAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIVVV 638

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYK 1359
             G+ + L V     P P   W    K++ +         +K   + TI+  E  D GIY 
Sbjct: 639  AGNKLRLDVPITGDPAPTVIWTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYS 698

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
            + + N  G    ++NV ++D P PP +  IL +   S  + WD P   G   II YV+E 
Sbjct: 699  VVVRNAAGEDTADINVKVVDVPDPPQEVKILSVGEESCVVQWDPPAFDGGQPIIGYVLER 758

Query: 1420 QEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            ++  +  W  ++     +T    + +    +Y  R YAVN + +S  S+ ++ +  +  T
Sbjct: 759  KKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFVPVAPT 818



 Score =  153 bits (371), Expect = 5e-35
 Identities = 160/642 (24%), Positives = 276/642 (42%), Gaps = 43/642 (6%)

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
            +   F++ L  +Y+  +G  + L  + ++     KW  N +E            G     
Sbjct: 337  KSAAFLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPTGRYIFESVGNMRYL 396

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D     C+V ++++++ L VKE     ++ L+D  V + D   LE E++ E 
Sbjct: 397  TINNCSLADDAAYCCVVGEEKSTSELFVKEPPVLIVKNLEDQMVMKGDRVELECEVSEEG 456

Query: 1045 ADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
            A+V WE+DG E+ + +  KY F+K G    L I + +  D G Y          AE+ V 
Sbjct: 457  ANVKWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVKTNGGESMAELLVQ 516

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            E   EI   + +  V   ++A F+ E++  +    W+K+G+E++    I +T  G+  KL
Sbjct: 517  EKELEIYQSIADLTVKAKDQALFKCEVSDENVRGTWYKNGAEVKPDARINITHIGRIHKL 576

Query: 1164 KIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRL--PEF------------IL 1207
             I D    D G+Y+          +A L   E  I++  R   P+             I+
Sbjct: 577  TIDDVKPGDEGDYTFVPDGYAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIV 636

Query: 1208 VPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI-IRKCTEDDQCE 1265
            V A     L V I  D    V W K + V+ + +    +   K   +  I      D+  
Sbjct: 637  VVAGNKLRLDVPITGDPAPTVIWTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGI 696

Query: 1266 YTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV--DYQAFP--QPND 1319
            Y+ V+ +A  + T  + V+VV+ P    D  +E +I    + + +V  D  AF   QP  
Sbjct: 697  YSVVVRNAAGEDTADINVKVVDVP----DPPQEVKILSVGEESCVVQWDPPAFDGGQPII 752

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMN 1374
             +++  K  K  +  + + D    + T +     +   Y++R+   N+ G   H+     
Sbjct: 753  GYVLERKKKKSYRWMRLNFDPYPET-TYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQP 811

Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNI 1433
               +   S P    + +I  +SI + W  PE  G+  +  Y VEY +  T EWI + + +
Sbjct: 812  FVPVAPTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPAAQGL 871

Query: 1434 T-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LK 1489
            T +T   I+NL T    +FR  A N    S A+ T      I+E  +Q P +  P    +
Sbjct: 872  TERTSLIIRNLTTGDRLQFRVRAYNMAGPSPAA-TLAQPITIREI-MQRPKILLPRNLRQ 929

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
             +     + + L   F G P+PKVTW ++G+ L +  A+  N
Sbjct: 930  TLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRN 971



 Score =  126 bits (304), Expect = 7e-27
 Identities = 117/493 (23%), Positives = 207/493 (41%), Gaps = 34/493 (6%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            G++  +   I G P P VIW K G K+  E D   ++ + +   +  I+  +R     Y+
Sbjct: 640  GNKLRLDVPITGDPAPTVIWTK-GEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYS 698

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            +   N AG  + ++ +KV D P  P+   I+  +  ES  ++W PP  DGG  +  Y +E
Sbjct: 699  VVVRNAAGEDTADINVKVVDVPDPPQEVKIL-SVGEESCVVQWDPPAFDGGQPIIGYVLE 757

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            + +  + RW+++        TY  +++ E   Y  RV A N +G S   ++    +  A 
Sbjct: 758  RKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFVPVA- 816

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXX 1821
              P+          I + S+ + W P E+ G   +  Y VE  +EG  +W          
Sbjct: 817  --PTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPAAQGLTER 874

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--QPRNF------V 1873
                I+ L+     QFR+ A N  G S   T    ITI + +  P    PRN        
Sbjct: 875  TSLIIRNLTTGDRLQFRVRAYNMAGPSPAATLAQPITIREIMQRPKILLPRNLRQTLIRR 934

Query: 1874 VSESTSRSVTLKW-TEPE---SNGGSPITNYIIEFKTVKGKS-----WTKIVTVGGSVHE 1924
            V ++ +  +  +    P+   S  G P+++ +   +  +G +      T+    G    +
Sbjct: 935  VGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRNSEGDTILFIRKTEKTHSGKYDLQ 994

Query: 1925 HCIENIKEKDEIIFRI--SAENTVGVS--LPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
              IEN+++   +  ++   +++ V  S    T +    L +   +P PP     + + G 
Sbjct: 995  VQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFLLIRVLDLPGPPEVLKIVDVWGF 1054

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            N+ +  W  P+ DG   + GY +   D     W  V           + DL   + Y+ R
Sbjct: 1055 NVAL-EWKPPKDDGNCEITGYTVQKADKKTMEWFTVYD-QYRRTHCIVSDLIMGNEYVFR 1112

Query: 2041 IYARNEIGLS-EP 2052
            ++A N +G S EP
Sbjct: 1113 VFANNLVGPSPEP 1125



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 64/211 (30%), Positives = 100/211 (47%), Gaps = 34/211 (16%)

Query: 1567 IQQKPVITISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            I Q+P I +   +++Q    +VGD   +    +G P P+V W KNG  L +    +I   
Sbjct: 915  IMQRPKILLPR-NLRQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLA-SIRNS 972

Query: 1625 EKTSVIRIKELKRSHSSKY--TIEASNTAGTSSVE------------------------V 1658
            E  +++ I++ +++HS KY   ++  N   T+SV                         +
Sbjct: 973  EGDTILFIRKTEKTHSGKYDLQVQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFL 1032

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             ++V D P  PE   I+ ++   +V +EWKPP DDG  E+T Y ++K +     W  V D
Sbjct: 1033 LIRVLDLPGPPEVLKIV-DVWGFNVALEWKPPKDDGNCEITGYTVQKADKKTMEWFTVYD 1091

Query: 1719 VDRDVETYCI-QKLNENCEYMFRVIAQNPVG 1748
              R   T+CI   L    EY+FRV A N VG
Sbjct: 1092 QYR--RTHCIVSDLIMGNEYVFRVFANNLVG 1120



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 18/160 (11%)

Query: 1912 WTK---IVTVG-GSVHE-----HCI---ENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
            WTK   +VT G G VH      HCI   E  + +DE I+ +   N  G    T   +V++
Sbjct: 659  WTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYSVVVRNAAGED--TADINVKV 716

Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
                 VP PP   ++I  VG    +  W  P +DGG P++GY +  +      WM +   
Sbjct: 717  ---VDVPDPPQE-VKILSVGEESCVVQWDPPAFDGGQPIIGYVLERKKKKSYRWMRLNFD 772

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
                  +  + + E   Y +R+YA N IG+S   ++ +PF
Sbjct: 773  PYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPF 812



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 63/348 (18%)

Query: 1295 REYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS--LTIKKVE 1351
            R+  I+R G  V L++ +Q  P+P   W  N + +     T  SI +      L I+K E
Sbjct: 928  RQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSS---TLASIRNSEGDTILFIRKTE 984

Query: 1352 NTDAGIYKLR--LENNCGHADVEMNVT------------------------ILDKPSPPG 1385
             T +G Y L+  +EN    A V + V                         +LD P PP 
Sbjct: 985  KTHSGKYDLQVQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFLLIRVLDLPGPPE 1044

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLK 1444
               I+++   ++ + W  P++ GN  I  Y V+  +  T EW +V     +T   + +L 
Sbjct: 1045 VLKIVDVWGFNVALEWKPPKDDGNCEITGYTVQKADKKTMEWFTVYDQYRRTHCIVSDLI 1104

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-------------------- 1484
              + Y FR +A N V  S     T+    I++T  Q P V                    
Sbjct: 1105 MGNEYVFRVFANNLVGPSPEPCGTKDSAYIQKTGGQQPHVVTSSGVVYKPPTHKEHDLSE 1164

Query: 1485 ----EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540
                 +PL + +        L+C   GVP+PKVTWY++   L   +A Y           
Sbjct: 1165 APKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSN-EAKYRMLSNHGVLTL 1223

Query: 1541 XX-----XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583
                        Y C A ND GE    C + ++ + +     E+ K++
Sbjct: 1224 EIRKPCPFDGGVYTCKAVNDSGEDTVECKLEVRSQIIKEDKKEESKKE 1271



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 497  VFEKPTSEEQSM--APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            V++ PT +E  +  AP F   L  +    G T    C V G P+P++TW++    +    
Sbjct: 1151 VYKPPTHKEHDLSEAPKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSNEA 1210

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
             ++M   +  V TL IR+  P D G +TC A N +G
Sbjct: 1211 KYRM-LSNHGVLTLEIRKPCPFDGGVYTCKAVNDSG 1245



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 46/225 (20%), Positives = 84/225 (37%), Gaps = 9/225 (4%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            + +  RN  G     T+D  + +     PP + +   V E    S  ++W  P  +GG P
Sbjct: 697  YSVVVRNAAGED---TADINVKVVDVPDPPQEVKILSVGEE---SCVVQWDPPAFDGGQP 750

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            I  Y++E K  K   W ++         +  + + E      R+ A N++G+S  +++  
Sbjct: 751  IIGYVLERKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQ 810

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
              +      P+     L +  +    ++  W  PE  G   L GY +         W+  
Sbjct: 811  PFV---PVAPTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPA 867

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +         IR+L+       R+ A N  G S      +P  +
Sbjct: 868  AQGLTERTSLIIRNLTTGDRLQFRVRAYNMAGPSPAATLAQPITI 912



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 48/182 (26%), Positives = 84/182 (46%), Gaps = 28/182 (15%)

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VL 725
           W   G E+ PD  I++     +H     L I +VK   EG YT V        S  +  L
Sbjct: 552 WYKNGAEVKPDARINITHIGRIHK----LTIDDVKPGDEGDYTFVPDGYAYNLSAKLNFL 607

Query: 726 KIKTG---EKEPPQV-IEPL-----KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
           ++K      ++PP++ ++ +      +++V  G  + L   + G+P PT+ W K  K V 
Sbjct: 608 EVKIDYVPRQDPPKIHLDCMGRTAESTIVVVAGNKLRLDVPITGDPAPTVIWTKGEKVV- 666

Query: 777 ALPTKSDGDT-------HSITILKPKKVKDEGVYTLKAENSEG--IAETSA-VITVEEPT 826
              T+ DG         H I  ++  + +DEG+Y++   N+ G   A+ +  V+ V +P 
Sbjct: 667 ---TEGDGRVHVESTKGHCIFTIEGAERQDEGIYSVVVRNAAGEDTADINVKVVDVPDPP 723

Query: 827 EE 828
           +E
Sbjct: 724 QE 725



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 73/281 (25%), Positives = 107/281 (38%), Gaps = 33/281 (11%)

Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
           K   A  V +G  I L    VA  + D+ WL  G+E  P        ES  +M    L I
Sbjct: 344 KLDPAYQVTKGHKIRLAVE-VANADADVKWLKNGQEFHPTGR--YIFESVGNM--RYLTI 398

Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSA 756
            N     +  Y  V    +  + L +        KEPP  +++ L+  +V +G+ V L  
Sbjct: 399 NNCSLADDAAYCCVVGEEKSTSELFV--------KEPPVLIVKNLEDQMVMKGDRVELEC 450

Query: 757 QVVGNPRPTITWCKNNKPVKALPT-----KSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           + V      + W K+   +    +     K DG  H I I+     +D G Y +K    E
Sbjct: 451 E-VSEEGANVKWEKDGVELTRDESFKYRFKKDGCKH-ILIINDATKEDCGHYKVKTNGGE 508

Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            +AE    + V+E   E            ++TVK K        V+   V   TWY+N  
Sbjct: 509 SMAE----LLVQEKELE------IYQSIADLTVKAKDQALFKCEVSDENVRG-TWYKNGA 557

Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
            + P   I     G   +L I +V    D GDY  V    A
Sbjct: 558 EVKPDARINITHIGRIHKLTIDDVKPG-DEGDYTFVPDGYA 597



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 68/303 (22%), Positives = 121/303 (39%), Gaps = 26/303 (8%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           P    K  + Q V +G  + LEC  V+    ++ W   G E+  DE+     + D   + 
Sbjct: 428 PVLIVKNLEDQMVMKGDRVELECE-VSEEGANVKWEKDGVELTRDESFKYRFKKDGCKH- 485

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            +L I +  K   G Y V     E  A L +       EKE  ++ + +  + V+  +  
Sbjct: 486 -ILIINDATKEDCGHYKVKTNGGESMAELLVQ------EKEL-EIYQSIADLTVKAKDQA 537

Query: 753 ILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
           +   +V  +     TW KN    KP   +     G  H +TI    K  DEG YT   + 
Sbjct: 538 LFKCEV-SDENVRGTWYKNGAEVKPDARINITHIGRIHKLTI-DDVKPGDEGDYTFVPDG 595

Query: 810 -SEGIAETSAVITVEEPTEENAEPPLF----INRFQE--ITVKEKGTIKLVARVTRNPVP 862
            +  ++     + V+       +PP      + R  E  I V     ++L   +T +P P
Sbjct: 596 YAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIVVVAGNKLRLDVPITGDPAP 655

Query: 863 SITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
           ++ W +  ++++  +     ++  G  I   I   + + D G Y  V  N+AG+ +    
Sbjct: 656 TVIWTKGEKVVTEGDGRVHVESTKGHCI-FTIEGAERQ-DEGIYSVVVRNAAGEDTADIN 713

Query: 921 VTI 923
           V +
Sbjct: 714 VKV 716



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 21/67 (31%), Positives = 35/67 (52%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G+P P+V WYKN   L N+ +Y + +      + I++        YT +A N +G  +
Sbjct: 1189 VRGVPKPKVTWYKNKMDLSNEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAVNDSGEDT 1248

Query: 1656 VEVTLKV 1662
            VE  L+V
Sbjct: 1249 VECKLEV 1255



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 48/186 (25%), Positives = 73/186 (39%), Gaps = 7/186 (3%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            E+ S  F  +L     V       L VE+ +   DV W K       T ++   S    R
Sbjct: 335  EKKSAAFLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPTGRYIFESVGNMR 394

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
             L I  C+  D   Y CV+ + KST++L V+  E P  IV    +  + +G  V L  + 
Sbjct: 395  YLTINNCSLADDAAYCCVVGEEKSTSELFVK--EPPVLIVKNLEDQMVMKGDRVELECEV 452

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
                  N +W  +   + + +  K     D     L I      D G YK++   N G +
Sbjct: 453  SE-EGANVKWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVK--TNGGES 509

Query: 1370 DVEMNV 1375
              E+ V
Sbjct: 510  MAELLV 515



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 2/82 (2%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
            E P+   PL S  V  G +  LS  V G P+P +TW KN   +           H +  L
Sbjct: 1164 EAPKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSNEAKYRMLSNHGVLTL 1223

Query: 793  KPKK--VKDEGVYTLKAENSEG 812
            + +K    D GVYT KA N  G
Sbjct: 1224 EIRKPCPFDGGVYTCKAVNDSG 1245



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 45/188 (23%), Positives = 83/188 (44%), Gaps = 9/188 (4%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G+ + L+  +   P P + W  KGE++V + +  V +ES    +C +  I   ++  EG 
Sbjct: 640 GNKLRLDVPITGDPAPTVIWT-KGEKVVTEGDGRVHVESTKG-HC-IFTIEGAERQDEGI 696

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           Y+VV  N  GE +  I +K+     +PPQ ++ L   +  +   V          +P I 
Sbjct: 697 YSVVVRNAAGEDTADINVKV-VDVPDPPQEVKILS--VGEESCVVQWDPPAFDGGQPIIG 753

Query: 768 WCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLK--AENSEGIAETSAVITVEE 824
           +    K  K+    + + D +  T  + K++ +   Y ++  A NS G++  S       
Sbjct: 754 YVLERKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFV 813

Query: 825 PTEENAEP 832
           P    +EP
Sbjct: 814 PVAPTSEP 821



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 9/91 (9%)

Query: 735  PQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHS 788
            P+++ P  L+  ++R+ G++V L     G PRP +TW KN +P+    A    S+GDT  
Sbjct: 919  PKILLPRNLRQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRNSEGDT-- 976

Query: 789  ITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            I  ++  +    G Y L+ +  E + +T++V
Sbjct: 977  ILFIRKTEKTHSGKYDLQVQ-IENVEDTASV 1006



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 22/64 (34%), Positives = 28/64 (43%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
            G+   FE E  K DA V+W  +  +I   N   +  DG K  L I      DA  Y+   
Sbjct: 24   GSSVVFEAETEKPDAKVKWQCNAKDIANGNKYTIAADGSKHSLSIKAVTHQDANIYAVIS 83

Query: 1181 GNSK 1184
            G SK
Sbjct: 84   GGSK 87



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 34/151 (22%), Positives = 58/151 (38%), Gaps = 5/151 (3%)

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGT 849
            +P   KD   Y  K    +    TS+ +  + PT +    +E P F       +V    T
Sbjct: 1124 EPCGTKDSA-YIQKTGGQQPHVVTSSGVVYKPPTHKEHDLSEAPKFTRPLVSRSVIAGYT 1182

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              L   V   P P +TWY+N   +S +E   +      +  +        D G Y C A 
Sbjct: 1183 ATLSCSVRGVPKPKVTWYKNKMDLS-NEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAV 1241

Query: 910  NSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
            N +G+ +   ++ +  + +   K  +   ET
Sbjct: 1242 NDSGEDTVECKLEVRSQIIKEDKKEESKKET 1272



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 2/59 (3%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283
            VTWYK K  + +  K+ ++S+    TL IRK    D   YTC  ++   + T + K+EV
Sbjct: 1197 VTWYKNKMDLSNEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAVNDSGEDTVECKLEV 1255


>UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole
            genome shotgun sequence; n=28; Euteleostei|Rep:
            Chromosome undetermined SCAF7373, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1090

 Score =  180 bits (438), Expect = 4e-43
 Identities = 204/895 (22%), Positives = 350/895 (39%), Gaps = 73/895 (8%)

Query: 831  EPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
            +PP F+ +    T VK      L  RV+ +   +I WY+N+  I+        F   +  
Sbjct: 196  KPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSAR 255

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            L + +   E DSG Y C   N AG +S  + +T+  E  +FVK      E   GK   L 
Sbjct: 256  LQLLSAAFE-DSGIYTCEVHNDAGSASCSSVLTVQ-EPPSFVK-TPSPLEGIRGKDASLH 312

Query: 950  CQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---- 1003
            C+   S      W   +K +      +II+ G             D GV +C V +    
Sbjct: 313  CEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT 372

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGE-IIKPKKN 1061
            + T T + +KE  P F++KL D  V   +   L   +  SE  D+ W +D + +++   N
Sbjct: 373  ESTRTAISLKEP-PAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDN 431

Query: 1062 K-YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIITRLQNQ 1116
            +   FEK   +  L +        G+Y+C L ++S  A     VT++E P  I+   ++ 
Sbjct: 432  RTITFEKS--VVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLE-PAAIVDSPESL 488

Query: 1117 KVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
             +  G     E+ +     L  RWFK   E+   N  Q++   K   LKI   D  DAGE
Sbjct: 489  NIQTGEAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGE 548

Query: 1176 YSCEVGN----SKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            Y  EV N    + CT  L V +  I  +F  +L +  LV   +       I    L  +W
Sbjct: 549  YKLEVSNHVGVASCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASW 608

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288
            +     I+    + +        L ++     D   YTC   +A  T++    V V  PP
Sbjct: 609  FHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPP 668

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
              V+         G++V+     +       +W   S+ +   +    S+    A+L + 
Sbjct: 669  SFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVATLVLN 728

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTIL----------DKPSPPGKPNILEIDSSS-- 1396
            KVE   AG Y  ++ N  G     + +++           D     GKP  LE+  +   
Sbjct: 729  KVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEVSFAGTP 788

Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS------IQNLKTNSSY 1449
             +N+ W +      ++ +Y V+     DT+  + V N  + + +      + N   N   
Sbjct: 789  RVNVTWKKDGGLIWASYLYNVIT---TDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVC 845

Query: 1450 RFRAYAVNEVDISDASETTEYYK--------VIKET--------KIQSPTVEKPLKNITT 1493
                  +      +  E+ E  +        +I+ T        K +     + LK+ T 
Sbjct: 846  EAHVSILERPSFVERMESVEINEGDSLLLRCLIEGTPEISVSWFKAEPVHFTRKLKDTTF 905

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXY 1548
               + ++L C + G P+  V W +DGK +  +     + T  +                Y
Sbjct: 906  TLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVLEILNSDRPAAGGTY 965

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWY 1607
             C   N  G  +    V ++ K   + +    +      G    + A + G  P  V WY
Sbjct: 966  ACAISNGAGSDKCHARVSLEHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQPLNVTWY 1025

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            K+ N++ +   Y ++     +++ +K   +S S  YT  ASN AG +S  V++ +
Sbjct: 1026 KDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTI 1080



 Score =  155 bits (375), Expect = 2e-35
 Identities = 179/789 (22%), Positives = 307/789 (38%), Gaps = 45/789 (5%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAI-PEP-DIAWLFKGEEIVPDENISVAIESD 687
            E +PPT         V       L C +    P P +++W   GEE+    +I+V   ++
Sbjct: 99   ELVPPTSPMVYTRSEVQLTEPNTLVCLVTGFYPAPVNVSWTRNGEEVTQGTSINVPYPNN 158

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIV 746
               +  + ++  V   Q+G      V        P + +  T   +PPQ ++ L  +  V
Sbjct: 159  EGTFTQISRLDFVP--QQGDIYSCRVQH------PALSEADTRMWKPPQFVQKLPPTTFV 210

Query: 747  RQGESVILSAQVVGNPRPTITWCKNN-KPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
            +  E   L  +V  +    I W KN+ K      TK   GD  +   L     +D G+YT
Sbjct: 211  KLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSARLQLLSAAFEDSGIYT 270

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             +  N  G A  S+V+TV+       EPP F+     +         L   V  +P   +
Sbjct: 271  CEVHNDAGSASCSSVLTVQ-------EPPSFVKTPSPLEGIRGKDASLHCEVAGSPPFQV 323

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TW +  +++  S        G ++ L I  ++ + D+G Y+C  SN+ G  S    +++ 
Sbjct: 324  TWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVD-DAGVYECQVSNNVGTESTRTAISLK 382

Query: 925  VEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYH-NKKEISGMDHREIIQEGRXX 982
             E   FVK L  +S    E  T+    + S  +   W   N   +   D+R I  E    
Sbjct: 383  -EPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVV 441

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVE 1039
                        G   C + +Q    + V   T+ E    +   +   ++  +   LEV 
Sbjct: 442  SLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQTGEAVALEVT 501

Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---- 1094
            I  S      W + G+      NKY       +  L I++    D GEY   + +     
Sbjct: 502  ICGSAELKTRWFK-GDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYKLEVSNHVGVA 560

Query: 1095 SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151
            SCT  + V +  +PP  I +L++  +  G     + ++     L   WF DG EI+    
Sbjct: 561  SCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKEIKSGLS 620

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFIL 1207
              ++      KL++      D G Y+C+     G S+ +A + V EP  +F         
Sbjct: 621  YDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPP-SFVETPEAQES 679

Query: 1208 VPANTDAYLTVEIPDETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            +P N  ++         L V W++  + ++        + D    TL++ K       EY
Sbjct: 680  LPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKD-DVATLVLNKVEMHHAGEY 738

Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            TC +L+        V + V  P   V   R+   ++G  + L V +   P+ N  W  + 
Sbjct: 739  TCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDG 798

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
             +I             S  L +   +  + AG Y   L+N  G+   E +V+IL++PS  
Sbjct: 799  GLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSILERPSFV 858

Query: 1385 GKPNILEID 1393
             +   +EI+
Sbjct: 859  ERMESVEIN 867



 Score =  144 bits (350), Expect = 2e-32
 Identities = 153/706 (21%), Positives = 296/706 (41%), Gaps = 45/706 (6%)

Query: 1046 DVVWERDGE-IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE-YSCILRDESCTAEVTVV 1103
            +V W R+GE + +       +           R   V  +G+ YSC ++  + +   T +
Sbjct: 135  NVSWTRNGEEVTQGTSINVPYPNNEGTFTQISRLDFVPQQGDIYSCRVQHPALSEADTRM 194

Query: 1104 ELPPEIITRLQNQKVNKGNKA-TFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
              PP+ + +L      K N+  + E  ++   +L + W+K+  +I    + +L       
Sbjct: 195  WKPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSA 254

Query: 1162 KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
            +L++     +D+G Y+CEV    G++ C+++LTV+EP  +F ++ P  +      DA L 
Sbjct: 255  RLQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQEPP-SF-VKTPSPLEGIRGKDASLH 312

Query: 1218 VEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
             E+       VTW K++ +++D+ K+ +I      TL I K   DD   Y C + +   T
Sbjct: 313  CEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT 372

Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHT 1334
               +  + ++ PP  V    +  +  G  +TL    +     +  WI  N  +++   + 
Sbjct: 373  ESTRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNR 432

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
              + +    SL + + ++  AG Y  RL N  G A    +VT+L+  +    P  L I +
Sbjct: 433  TITFEKSVVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQT 492

Query: 1395 SSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFR 1452
                    E    G++ +   +    +E+       + +  K  T  IQ+     +  ++
Sbjct: 493  GEAVAL--EVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYK 550

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQP 1511
                N V ++  + T     +    K+  P+  + L++      +  +L C + G  P  
Sbjct: 551  LEVSNHVGVASCTVT-----LAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLT 605

Query: 1512 KVTWYRDGKKLKTAKA---TY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
              +W+ DGK++K+  +   +Y +N                Y C A N  G  ETS  V +
Sbjct: 606  -ASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNV 664

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
             + P    + E   Q+   G+     A + G  P +V W++   ++ + +  +I+ K+  
Sbjct: 665  AEPPSFVETPE--AQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDV 722

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---------SKPEGPVIMREI 1678
            + + + +++  H+ +YT +  N  G  S  V L V +           S  +G  +  E+
Sbjct: 723  ATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEV 782

Query: 1679 S---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            S      V + WK    DGGL    Y       D +  ++V + DR
Sbjct: 783  SFAGTPRVNVTWK---KDGGLIWASYLYNVITTDTSCILEVLNSDR 825



 Score =  123 bits (297), Expect = 5e-26
 Identities = 141/675 (20%), Positives = 269/675 (39%), Gaps = 40/675 (5%)

Query: 1017 PEFIRKLQDFE-VKEKDVAILEVEINS-ETADVVW-ERDGEIIKPKKNKYDFEKRGHIRK 1073
            P+F++KL     VK  +   LE  ++S ++ ++ W + D +I      K  F       +
Sbjct: 198  PQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLS--AR 255

Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
            L + + +  D G Y+C + ++    SC++ +TV E PP  +      +  +G  A+   E
Sbjct: 256  LQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQE-PPSFVKTPSPLEGIRGKDASLHCE 314

Query: 1130 LTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT-- 1186
            +       V W K+   ++ S   ++   G    L I   ++DDAG Y C+V N+  T  
Sbjct: 315  VAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGTES 374

Query: 1187 --AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS-VIEDTEKFT 1243
                ++++EP       + + ++V        TV+   E LD++W +    V+ D +  T
Sbjct: 375  TRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVK-GSEPLDISWIQDNDHVLRDGDNRT 433

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK-IVDYEREYRIKRG 1302
            +  +    +LI+ +       +YTC L +          V    P  IVD      I+ G
Sbjct: 434  ITFEKSVVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQTG 493

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
              V L V      +    W    + +      + S   K A+L I+  +  DAG YKL +
Sbjct: 494  EAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYKLEV 553

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIY-YVVEYQ 1420
             N+ G A   + + + DK  PP     L      +    D + +  G++ +   +  + +
Sbjct: 554  SNHVGVASCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGK 613

Query: 1421 EIDT--TEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
            EI +  +  IS V NI K +  +Q ++T    R+   A N    S+ S +    +    +
Sbjct: 614  EIKSGLSYDISYVDNICKLR--LQTVQTTDGGRYTCKAANAAGTSETSASVNVAE--PPS 669

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRX 1533
             +++P  ++ L      P  ++       G    KV W+R  +++   +  +    ++  
Sbjct: 670  FVETPEAQESL------PGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVA 723

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y C   N  G+      + +++         DI  +   G    + 
Sbjct: 724  TLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEK--GKPLRLE 781

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS-KYTIEASNTAG 1652
                G P   V W K+G  +     YN+ T + + ++ +    R  ++  Y+    N  G
Sbjct: 782  VSFAGTPRVNVTWKKDGGLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVG 841

Query: 1653 TSSVEVTLKVYDKPS 1667
                E  + + ++PS
Sbjct: 842  NDVCEAHVSILERPS 856



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 58/195 (29%), Positives = 88/195 (45%), Gaps = 10/195 (5%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS---I 789
            EP      LK      G+ + L     G+PR ++ W K+ KP+ A    +   T+S   +
Sbjct: 892  EPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVL 951

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG- 848
             IL   +    G Y     N  G  +  A +++E  T      P F  R  E  V  +G 
Sbjct: 952  EILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKT-----APSFTRRPPESLVDSEGK 1006

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            T+K+ ARV+ +   ++TWY++N  I        +F   N+ ++     S+  SG Y C A
Sbjct: 1007 TVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSF-VNNLAILCLKNSSKSQSGVYTCSA 1065

Query: 909  SNSAGKSSHGARVTI 923
            SN AGK+S    VTI
Sbjct: 1066 SNEAGKASCLVSVTI 1080



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 59/307 (19%), Positives = 126/307 (41%), Gaps = 19/307 (6%)

Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
           +  +  +L ++   +  G   T             A +    PP+F + P+AQ    G++
Sbjct: 625 YVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPPSFVETPEAQESLPGNN 684

Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
           +    ++       + W     E++      ++++ D+    + L +  V+    G YT 
Sbjct: 685 VSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDV----ATLVLNKVEMHHAGEYTC 740

Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
             +N  G+ S P+ L ++    EP   ++ L+ +   +G+ + L     G PR  +TW K
Sbjct: 741 QVLNPVGKKSYPVYLSVR----EPVHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKK 796

Query: 771 NNKPVKA--LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
           +   + A  L      DT  I  +L   +++  G Y+   +N  G     A +++     
Sbjct: 797 DGGLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSI----- 851

Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GE 886
              E P F+ R + + + E  ++ L   +   P  S++W++   +    +     F  G+
Sbjct: 852 --LERPSFVERMESVEINEGDSLLLRCLIEGTPEISVSWFKAEPVHFTRKLKDTTFTLGQ 909

Query: 887 NIELVIT 893
            ++L+ T
Sbjct: 910 PLQLLCT 916



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 76/325 (23%), Positives = 125/325 (38%), Gaps = 21/325 (6%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
            FV+KLR      G  ++ E    G PR  +TW +   +I  S  + +   D +    V+ 
Sbjct: 763  FVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGGLIWASYLYNVITTDTSCILEVLN 822

Query: 572  EVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP--------LSDHGSEMTVXXXXXXXXX 622
                E AGT++C   N  G       + I+E P        +  +  +  +         
Sbjct: 823  SDRMEAAGTYSCHLDNGVGNDVCEAHVSILERPSFVERMESVEINEGDSLLLRCLIEGTP 882

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                   +  P  F++K K      G  + L C     P   +AW   G+ I      +V
Sbjct: 883  EISVSWFKAEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNV 942

Query: 683  AIESDMHMYCSVLKITNV-KKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE 739
               +     C VL+I N  +    GTY     N  G  +    + L+ KT    P     
Sbjct: 943  RTTNSS---C-VLEILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKTA---PSFTRR 995

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI--LKPKKV 797
            P +S++  +G++V + A+V G+    +TW K+N  + +         +++ I  LK    
Sbjct: 996  PPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSK 1055

Query: 798  KDEGVYTLKAENSEGIAETSAVITV 822
               GVYT  A N  G A     +T+
Sbjct: 1056 SQSGVYTCSASNEAGKASCLVSVTI 1080



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 3/190 (1%)

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
            AEP  F  + ++ T      ++L+   + +P  S+ W ++ + I  S          +  
Sbjct: 891  AEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCV 950

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVIL 948
            L I N D     G Y C  SN AG     ARV+++ +   +F +   +S    EGKTV +
Sbjct: 951  LEILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKTAPSFTRRPPESLVDSEGKTVKI 1010

Query: 949  ECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
            E +   S  ++  WY +  EI    + E+                   GV  C   ++  
Sbjct: 1011 EARVSGSQPLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAG 1070

Query: 1007 STMLVVKETI 1016
                +V  TI
Sbjct: 1071 KASCLVSVTI 1080



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 1/101 (0%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           ++ + P F+ KLR  H   G +   +C+V G      +WF     IK    + + Y  DN
Sbjct: 570 DKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKEIKSGLSYDISY-VDN 628

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           +  L ++ V   D G +TC A NAAG + ++  + V  P S
Sbjct: 629 ICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPPS 669



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P FV+   P     G      C+V G P  Q+TW ++  ++K S+ +++     +V TL 
Sbjct: 292 PSFVKTPSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSV-TLH 350

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           I ++  +DAG + C   N  G  S+ T + ++ P
Sbjct: 351 IIKLEVDDAGVYECQVSNNVGTESTRTAISLKEP 384



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 503  SEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            S E   AP F  +  P+   D  G TV+ E +V G     +TW++    I    +++M +
Sbjct: 983  SLEHKTAPSFTRR-PPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSF 1041

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
             + N+A L ++      +G +TC A N AG AS    + +    + H
Sbjct: 1042 VN-NLAILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTISGMSASH 1087



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 1/106 (0%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
           E   S   +  P FVE    + +  G+ V F  +V G    ++ WFR +  +   +   +
Sbjct: 657 ETSASVNVAEPPSFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHI 716

Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
              DD VATLV+ +V    AG +TC   N  G  S    L V  P+
Sbjct: 717 SLKDD-VATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPV 761



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 2/97 (2%)

Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           P FV+KL P            EC+V       I W++    I    + ++ + D +    
Sbjct: 198 PQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSARLQ 257

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           ++   F ED+G +TC   N AG AS ++ L V+ P S
Sbjct: 258 LLSAAF-EDSGIYTCEVHNDAGSASCSSVLTVQEPPS 293



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 22/94 (23%), Positives = 40/94 (42%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P FV+KL  +    G  +     V+G     I+W +    +    D +    + +V +L+
Sbjct: 385 PAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLI 444

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           + +     AG +TC   N +G A S   + +  P
Sbjct: 445 VPQADSATAGKYTCRLSNQSGVALSVCHVTLLEP 478


>UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA;
            n=1; Tribolium castaneum|Rep: PREDICTED: similar to
            CG33484-PA - Tribolium castaneum
          Length = 3764

 Score =  178 bits (434), Expect = 1e-42
 Identities = 199/749 (26%), Positives = 308/749 (41%), Gaps = 96/749 (12%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T  E + AP F+  L       G  ++ EC+V G P P +TW      ++          
Sbjct: 1545 TPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTHNGKALQ---------F 1595

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
            + N ATL++ E FP+DAGT+   AKN AG ASS   + V+  L    S+  +        
Sbjct: 1596 EGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSDSEL-------- 1647

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                A  +E + P+         V EG+ + L+C +V  PEP++ W      +    +  
Sbjct: 1648 ----ASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQ 1703

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI------KTGEKE-- 733
            +  + D    CS++ I        G Y VVA+N  GEAS    L +      K  E E  
Sbjct: 1704 LLFQGDR---CSLI-IQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEP 1759

Query: 734  ---PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI- 789
               PP+  + L  ++V +GE V     V G P P I W  NN+P+   PT     TH+  
Sbjct: 1760 PGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPIT--PTDHVKITHNSD 1817

Query: 790  -TI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTE-----ENAEPPLFINR 838
             TI   +   + +D+GVYT+KA NS G A+  A + V+  +P E     E    P F   
Sbjct: 1818 GTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKEL 1877

Query: 839  FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
            F +    E  + K    V   P P + W  N E I+  + +     G+   L I  +  +
Sbjct: 1878 FNDRVAFEGTSTKFECIVVGKPTPKVRWLFNGEPITGRKILIST-SGDRQVLTIPEISKD 1936

Query: 899  IDSGDYKCVASNSAGKSSHGARVTI-DVEKVT-------FVKHLQKSYETEEGKTVILEC 950
            ++ G   CVA N  GK+S  A +++  V  +T         +H++ SY            
Sbjct: 1937 LE-GTITCVAENEVGKASCAAHLSVQSVSTITLPEFSRDISQHVESSYILNREVHTQSST 1995

Query: 951  QTSHTVST--------KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
             TS  + T           H+  +      ++I QE               VG     + 
Sbjct: 1996 STSRKMETFTGTQEPQVQVHSFSQKDQQSFKQINQEAPQISESHKIEEYHQVGKQPPTII 2055

Query: 1003 DQETS------TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER--DG- 1053
            ++ +S      T    ++TI   + K        K +  +  +I  +  DVV E   DG 
Sbjct: 2056 EKSSSLFTTGTTEETKQKTIEHVVHKPVIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQ 2115

Query: 1054 ---EIIKPKKNKYDFEKRG---HIRK----LYIRNTSVHDEGEYSCILRDES----CTAE 1099
               EI   K  +   E  G   H  +    + I+N ++ D G Y+C   +E+     TA+
Sbjct: 2116 PTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNEAGKAISTAD 2175

Query: 1100 VTV--VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEI--QFSNHIQL 1154
            + V     PP    RLQ Q V KG++   E+E+T   D  V W+KDG  I     +  ++
Sbjct: 2176 LVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARI 2235

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
               G    L I   +L+ +G +     NS
Sbjct: 2236 RSMGNSHTLVIEKAELNMSGRFMVRAVNS 2264



 Score =  153 bits (371), Expect = 5e-35
 Identities = 135/494 (27%), Positives = 212/494 (42%), Gaps = 61/494 (12%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+F   L      +GS   F C V G P P +TWF+    I+ + D+Q  +D   + TL
Sbjct: 1353 APVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQ-GLCTL 1411

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
             I E F ED+  +TC A NAAG A ++  L V+   ++   +++                
Sbjct: 1412 TIEETFAEDSAKYTCKAINAAGSAETSACLSVKE--TEPEEQLS---------------- 1453

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                PPTF K  +     EG+     C++   P P + W FK  E + +    V   ++ 
Sbjct: 1454 ----PPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQW-FKNYECIDNSPDYVITYNNG 1508

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVR 747
                ++LK   V    +  YT  A N  G A     L +   E  E P+ I PL +++ R
Sbjct: 1509 E---AILKFDKVSLEDKAEYTCKATNELGVAQSTASLTVTPLEPTEAPKFILPLSNVMAR 1565

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             G+ + L  +V G P P +TW  N K +     + +G+  ++ + +    KD G Y + A
Sbjct: 1566 AGQKIKLECEVSGLPPPILTWTHNGKAL-----QFEGNKATLLVFEAFP-KDAGTYVVNA 1619

Query: 808  ENSEGIAETSAVITVEE--PTE-------ENAEP--PLFINRFQEITVKEKGTIKLVARV 856
            +N  G A ++  ++V+   PTE        + EP  P        ++V E   ++L   +
Sbjct: 1620 KNIAGEASSACSVSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVI 1679

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
               P P + WY ++  +  S      F G+   L+I     E D+G YK VA NSAG++S
Sbjct: 1680 VGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQEALPE-DAGQYKVVALNSAGEAS 1738

Query: 917  HGARVTIDVEKVT--------------FVKHLQKSYETEEGKTVILECQTSH-TVSTKWY 961
                +T+  +  T              F K L     +E  K     C T   T   KW 
Sbjct: 1739 SKCSLTVVPDSGTKPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWL 1798

Query: 962  HNKKEISGMDHREI 975
             N + I+  DH +I
Sbjct: 1799 LNNQPITPTDHVKI 1812



 Score =  118 bits (283), Expect = 2e-24
 Identities = 127/491 (25%), Positives = 195/491 (39%), Gaps = 52/491 (10%)

Query: 500  KPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
            KP   E+     P F + L      +G  V+FE  V G P P+I W      I P+   +
Sbjct: 1752 KPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVK 1811

Query: 558  MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
            + ++ D    L I  V PED G +T  A N++G A    +LIV++               
Sbjct: 1812 ITHNSDGTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPE---------- 1861

Query: 618  XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
                     +I  G  P+F +    +   EG+    EC +V  P P + WLF GE I   
Sbjct: 1862 ----IIKHEEIKSG--PSFKELFNDRVAFEGTSTKFECIVVGKPTPKVRWLFNGEPIT-G 1914

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732
              I ++   D      VL I  + K  EGT T VA N  G+AS    L ++     T  +
Sbjct: 1915 RKILISTSGDR----QVLTIPEISKDLEGTITCVAENEVGKASCAAHLSVQSVSTITLPE 1970

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK-PVKALPTKSDGDTHSITI 791
                + + ++S  +   E    S+        T T  +  +  V +   K       I  
Sbjct: 1971 FSRDISQHVESSYILNREVHTQSSTSTSRKMETFTGTQEPQVQVHSFSQKDQQSFKQINQ 2030

Query: 792  LKPKKVKDEGV--YTLKAENSEGIAETSAVI----TVEEPTEENAE-----------PPL 834
              P+  +   +  Y    +    I E S+ +    T EE  ++  E           PP 
Sbjct: 2031 EAPQISESHKIEEYHQVGKQPPTIIEKSSSLFTTGTTEETKQKTIEHVVHKPVIKTRPPK 2090

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            FI       V +   + L   V   P P ITW +N E +  S  +  +FD   + +VI N
Sbjct: 2091 FITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKN 2150

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTI--DVEKVTFVKHLQKSYETEEGKTVILECQT 952
               + D+G Y C A N AGK+   A + +   V    F + LQ +   ++G  VI+E + 
Sbjct: 2151 ATID-DAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQ-AQVVKKGDRVIMEVEV 2208

Query: 953  SHT--VSTKWY 961
            + T   +  WY
Sbjct: 2209 TGTPDPTVTWY 2219



 Score =  116 bits (278), Expect = 9e-24
 Identities = 133/527 (25%), Positives = 219/527 (41%), Gaps = 60/527 (11%)

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
            EA+    L+ +  + E P    PL   I+++G        V G P P +TW K+   ++ 
Sbjct: 1337 EAARIQALEAQKPKIEAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQN 1396

Query: 778  LP---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT-EENAEPP 833
             P   T  D    ++TI +    +D   YT KA N+ G AETSA ++V+E   EE   PP
Sbjct: 1397 NPDYQTTFDQGLCTLTI-EETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPP 1455

Query: 834  LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELV 891
             F+   +  + +E    +   +V  NP+P++ W++N E I  SP   IT N +GE I L 
Sbjct: 1456 TFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYN-NGEAI-LK 1513

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI----DVEKVTFVKHLQKSYETEEGKTVI 947
               V  E D  +Y C A+N  G +   A +T+      E   F+  L  +     G+ + 
Sbjct: 1514 FDKVSLE-DKAEYTCKATNELGVAQSTASLTVTPLEPTEAPKFILPL-SNVMARAGQKIK 1571

Query: 948  LECQTSHTVS--TKWYHNKK--EISGMDHREIIQEG----------RXXXXXXXXXXXXD 993
            LEC+ S        W HN K  +  G     ++ E                         
Sbjct: 1572 LECEVSGLPPPILTWTHNGKALQFEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACS 1631

Query: 994  VGVIKCIVKDQETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILE-VEINSETADVVWER 1051
            V V   +  +   S +    E + P     L +  V E +   L+ V +     +V+W  
Sbjct: 1632 VSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYH 1691

Query: 1052 DGEIIKPKKNKYDFEK--RGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVE- 1104
            D    +P K   DF+   +G    L I+     D G+Y  +      + S    +TVV  
Sbjct: 1692 DD---RPVKESPDFQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPD 1748

Query: 1105 -------------LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN 1150
                          PP+    L +  V++G K  FE  +T +    ++W  +   I  ++
Sbjct: 1749 SGTKPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTD 1808

Query: 1151 HIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192
            H+++T +     +L+I +   +D G Y+ +     G++KC A L V+
Sbjct: 1809 HVKITHNSDGTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVK 1855



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 65/206 (31%), Positives = 107/206 (51%), Gaps = 11/206 (5%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +++  PP F      + VD+  D++LE  +   P P+I W   GE++   E+  V I  D
Sbjct: 2083 VIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQL--RESSGVQIHFD 2140

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             +    V+K   +     G YT  AVN  G+A     L ++     PP     L++ +V+
Sbjct: 2141 RNKVSVVIKNATID--DAGRYTCTAVNEAGKAISTADLVVRK-TVFPPVFGRRLQAQVVK 2197

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK----SDGDTHSITILKPKKVKDEGV 802
            +G+ VI+  +V G P PT+TW K+  P+ +AL  K    S G++H++ I K  ++   G 
Sbjct: 2198 KGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEK-AELNMSGR 2256

Query: 803  YTLKAENSEGIAETSAVITVEEPTEE 828
            + ++A NS G A++ A I V EPT +
Sbjct: 2257 FMVRAVNSGGEAQSIADIAVFEPTPD 2282



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 94/441 (21%), Positives = 173/441 (39%), Gaps = 41/441 (9%)

Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
            +++ +     + A    K K+E   F   + D      I+ GS  T +      P P   
Sbjct: 1331 EEEAKLEAARIQALEAQKPKIEAPVFTSPLSDAI----IQEGSRFTFMCHVTGTPVPVVT 1386

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD- 1379
            W  +   I+     + + D    +LTI++    D+  Y  +  N  G A+    +++ + 
Sbjct: 1387 WFKDGISIQNNPDYQTTFDQGLCTLTIEETFAEDSAKYTCKAINAAGSAETSACLSVKET 1446

Query: 1380 KP----SPPGKPNILEIDSSSINICWD---EPENTGNSTIIYYVVEYQEIDTT-EWISVK 1431
            +P    SPP    +LE  S+     +    + E     T+ ++   Y+ ID + +++   
Sbjct: 1447 EPEEQLSPPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFK-NYECIDNSPDYVITY 1505

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            N  +       +       +   A NE+ ++   ++T    V      ++P    PL N+
Sbjct: 1506 NNGEAILKFDKVSLEDKAEYTCKATNELGVA---QSTASLTVTPLEPTEAPKFILPLSNV 1562

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
                 + I+L C   G+P P +TW  +GK L+       N+               Y   
Sbjct: 1563 MARAGQKIKLECEVSGLPPPILTWTHNGKALQFE----GNKATLLVFEAFPKDAGTYVVN 1618

Query: 1552 AFNDHGEVETSCVVGIQQK-PVITISNEDIKQKHKV---------------GDEWLVTAV 1595
            A N  GE  ++C V ++ + P  T  +E       V               G+   +  V
Sbjct: 1619 AKNIAGEASSACSVSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCV 1678

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P PEVIWY +   ++   ++ +  +     + I+E     + +Y + A N+AG +S
Sbjct: 1679 IVGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEAS 1738

Query: 1656 VEVTLKVY----DKPSKPEGP 1672
             + +L V      KP +PE P
Sbjct: 1739 SKCSLTVVPDSGTKPPEPEEP 1759



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 139/635 (21%), Positives = 239/635 (37%), Gaps = 72/635 (11%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P   + L +  + +G++ TF   +T     +V WFKDG  IQ +   Q T D     L I
Sbjct: 1354 PVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQGLCTLTI 1413

Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFI--LVP------ANTD 1213
             +   +D+ +Y+C+     G+++ +A L+V+E      L  P F+  L P      A   
Sbjct: 1414 EETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPPTFVKLLEPGSAREGAGFQ 1473

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD- 1272
             Y  VE  +    V W+K    I+++  + +  +  +  L   K + +D+ EYTC   + 
Sbjct: 1474 FYCKVE-GNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYTCKATNE 1532

Query: 1273 ---AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
               A+ST  L V  +E    PK +        + G  + L  +    P P   W  N K 
Sbjct: 1533 LGVAQSTASLTVTPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTHNGKA 1592

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPPGK 1386
            ++         +   A+L + +    DAG Y +  +N  G A    +V++  + P+    
Sbjct: 1593 LQ--------FEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSD 1644

Query: 1387 PNI---LEIDSSSINICWDEPENT-GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ- 1441
              +   +E    SI +       T GN   +  V+  Q      W       K     Q 
Sbjct: 1645 SELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQL 1704

Query: 1442 -------NLKTNSSYRFRAYAVNEVDISDASETTE--YYKVIKETKIQSPTVEKP----- 1487
                   +L    +    A     V ++ A E +      V+ ++  + P  E+P     
Sbjct: 1705 LFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEPPGTPP 1764

Query: 1488 -----LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATY--ENRXXXXX 1537
                 L ++     E +E      G P P++ W  + + +      K T+  +       
Sbjct: 1765 KFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTIRLEI 1824

Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQ--------KHKVGD 1588
                      Y   A N  G+ +    + ++  KP   I +E+IK           +V  
Sbjct: 1825 ANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFNDRVAF 1884

Query: 1589 EWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            E   T    ++ G P P+V W  NG  +   ++  I+T     V+ I E+ +      T 
Sbjct: 1885 EGTSTKFECIVVGKPTPKVRWLFNGEPI-TGRKILISTSGDRQVLTIPEISKDLEGTITC 1943

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
             A N  G +S    L V    S    P   R+IS+
Sbjct: 1944 VAENEVGKASCAAHLSV-QSVSTITLPEFSRDISQ 1977



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 9/194 (4%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITI- 791
            PP+ I P+   IV Q   V+L   V G P P ITW KN + ++ +   +   D + +++ 
Sbjct: 2088 PPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVV 2147

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
            +K   + D G YT  A N  G A ++A + V +       PP+F  R Q   VK+   + 
Sbjct: 2148 IKNATIDDAGRYTCTAVNEAGKAISTADLVVRK----TVFPPVFGRRLQAQVVKKGDRVI 2203

Query: 852  LVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            +   VT  P P++TWY++   I  +  +       G +  LVI   +  + SG +   A 
Sbjct: 2204 MEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNM-SGRFMVRAV 2262

Query: 910  NSAGKSSHGARVTI 923
            NS G++   A + +
Sbjct: 2263 NSGGEAQSIADIAV 2276



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 36/97 (37%), Positives = 54/97 (55%), Gaps = 1/97 (1%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            +  + AP+F+  LR      G   +FEC V+  P P I W +   II+ S D+Q++Y  +
Sbjct: 3570 QSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHY-RN 3628

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             V  L I + +PEDAGT+ C A N+ G  ++T  L V
Sbjct: 3629 GVCRLTISQAYPEDAGTYACTATNSVGTVNTTATLEV 3665



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 50/216 (23%), Positives = 92/216 (42%), Gaps = 13/216 (6%)

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYEN 1531
            ++ KI++P    PL +   +        C   G P P VTW++DG  ++     + T++ 
Sbjct: 1347 QKPKIEAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQ 1406

Query: 1532 RX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQ-----KH 1584
                             Y C A N  G  ETS  + +++ +P   +S     +       
Sbjct: 1407 GLCTLTIEETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPPTFVKLLEPGSA 1466

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G  +     +EG P P V W+KN   ++N  +Y IT     ++++  ++     ++YT
Sbjct: 1467 REGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYT 1526

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKP-EGPVIMREIS 1679
             +A+N  G +    +L V   P +P E P  +  +S
Sbjct: 1527 CKATNELGVAQSTASLTV--TPLEPTEAPKFILPLS 1560



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 38/97 (39%), Positives = 50/97 (51%), Gaps = 1/97 (1%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            EEQ   P FV+ L P    +G+  QF C+VEG P P + WF+    I  S D+ + Y++ 
Sbjct: 1449 EEQLSPPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYNNG 1508

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              A L   +V  ED   +TC A N  G A ST  L V
Sbjct: 1509 E-AILKFDKVSLEDKAEYTCKATNELGVAQSTASLTV 1544



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 41/195 (21%), Positives = 85/195 (43%), Gaps = 9/195 (4%)

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRX 1533
            K + P    P+     + N D+ L  I  G P P++TW ++G++L+ +         N+ 
Sbjct: 2085 KTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKV 2144

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592
                          Y C A N+ G+  ++  + +++     +    ++ Q  K GD  ++
Sbjct: 2145 SVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIM 2204

Query: 1593 TAVIEGIPPPEVIWYKNG---NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
               + G P P V WYK+G    +   DK   I +   +  + I++ + + S ++ + A N
Sbjct: 2205 EVEVTGTPDPTVTWYKDGVPIGEALGDKA-RIRSMGNSHTLVIEKAELNMSGRFMVRAVN 2263

Query: 1650 TAGTSSVEVTLKVYD 1664
            + G +     + V++
Sbjct: 2264 SGGEAQSIADIAVFE 2278



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 48/184 (26%), Positives = 81/184 (44%), Gaps = 8/184 (4%)

Query: 1207 LVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
            +V  N D  L   +  + T ++TW K    + ++    +  D  K +++I+  T DD   
Sbjct: 2099 IVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGR 2158

Query: 1266 YTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            YTC  ++    A ST  L V    FPP      +   +K+G  V + V+    P P   W
Sbjct: 2159 YTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTW 2218

Query: 1322 IVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
              +   I +    K  I S   S +L I+K E   +G + +R  N+ G A    ++ + +
Sbjct: 2219 YKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFE 2278

Query: 1380 KPSP 1383
             P+P
Sbjct: 2279 -PTP 2281



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 26/92 (28%), Positives = 44/92 (47%)

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            +++  PPP ++W KNG  +EN  +Y +  +     + I +     +  Y   A+N+ GT 
Sbjct: 3598 IVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTISQAYPEDAGTYACTATNSVGTV 3657

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            +   TL+V   PS   G     +  R SV+ E
Sbjct: 3658 NTTATLEVPGVPSHMYGTYRQLKTGRRSVSPE 3689



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 49/166 (29%), Positives = 78/166 (46%), Gaps = 19/166 (11%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            PP+ IT +  + V++      E  +  G     + W K+G +++ S+ +Q+  D  K  +
Sbjct: 2088 PPKFITPVMGKIVDQNVDVVLE-GIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSV 2146

Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTVEE---PSINFTLRLPEFILVPANTDAYL 1216
             I +  +DDAG Y+C    E G +  TA L V +   P + F  RL +  +V       +
Sbjct: 2147 VIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPV-FGRRL-QAQVVKKGDRVIM 2204

Query: 1217 TVEI---PDETLDVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRK 1257
             VE+   PD T  VTWYK    I +   +K  + S     TL+I K
Sbjct: 2205 EVEVTGTPDPT--VTWYKDGVPIGEALGDKARIRSMGNSHTLVIEK 2248



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 62/263 (23%), Positives = 104/263 (39%), Gaps = 21/263 (7%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATL 568
            P+F  +L+ +    G  V  E +V G P P +TW++    I +   D        N  TL
Sbjct: 2185 PVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTL 2244

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM--TV--XXXXXXXXXXX 624
            VI +     +G F   A N+ G A S  ++ V  P  D   E+  TV             
Sbjct: 2245 VIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFEPTPDTMVEVVKTVVFEDVRKHETLTS 2304

Query: 625  XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI---AWLFKGEEIVPDENIS 681
             AD +     T  K  +   + E S +       ++ + +I   +   K E  VP+  + 
Sbjct: 2305 AADKVSSTVSTIPKPVEIPKIPESSHVSSRSEFTSMTKQEISKESKTMKFEHTVPEIPMP 2364

Query: 682  ------VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-EKEP 734
                  + +E+D  +     +I   KK +E      +++++       V KIK G E  P
Sbjct: 2365 RVPTPVLKLETDYQICQPSSEIIQEKKVEETGIETSSISKQSSLQY-FVKKIKEGDEPVP 2423

Query: 735  PQVIE-----PLKSMIVRQGESV 752
            P + E     P+K  + ++ E V
Sbjct: 2424 PPLKETTIPVPIKPEVYKKFEEV 2446



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 1/87 (1%)

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
            + +A  P+FI   + I V      K    V   P P+I W +N  II  S     ++   
Sbjct: 3570 QSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNG 3629

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAG 913
               L I+    E D+G Y C A+NS G
Sbjct: 3630 VCRLTISQAYPE-DAGTYACTATNSVG 3655



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1107 PEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  IT L+N  V  G  A FE I  ++    + W K+G  I+ SN  QL       +L I
Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTI 3635

Query: 1166 YDCDLDDAGEYSCEVGNSKCT--AILTVEEPSI 1196
                 +DAG Y+C   NS  T     T+E P +
Sbjct: 3636 SQAYPEDAGTYACTATNSVGTVNTTATLEVPGV 3668



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 720  SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779
            S P   K+       P  I PL+++ V  G+       V   P P I W KN + ++   
Sbjct: 3561 STPGSTKVLQSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIE--- 3617

Query: 780  TKSDGDTH------SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
              +D   H       +TI +    +D G Y   A NS G   T+A + V
Sbjct: 3618 NSNDYQLHYRNGVCRLTISQAYP-EDAGTYACTATNSVGTVNTTATLEV 3665



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 3/92 (3%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P FI  L++  V     A  E  + SE   +++W ++G II+   N Y    R  + +L 
Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIE-NSNDYQLHYRNGVCRLT 3634

Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVT-VVELP 1106
            I      D G Y+C   +   T   T  +E+P
Sbjct: 3635 ISQAYPEDAGTYACTATNSVGTVNTTATLEVP 3666



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 21/102 (20%), Positives = 40/102 (39%), Gaps = 4/102 (3%)

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE 1530
            + ++  ++P    PL+NI     +  +  CI    P P + W ++G+ ++ +   +  Y 
Sbjct: 3568 VLQSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYR 3627

Query: 1531 NRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            N                 Y C A N  G V T+  + +   P
Sbjct: 3628 NGVCRLTISQAYPEDAGTYACTATNSVGTVNTTATLEVPGVP 3669


>UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA;
            n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
            GA13389-PA - Nasonia vitripennis
          Length = 1541

 Score =  176 bits (428), Expect = 6e-42
 Identities = 111/392 (28%), Positives = 189/392 (48%), Gaps = 16/392 (4%)

Query: 1381 PSPPGKPNIL--EIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
            P+PPGKP ++  E D+    + I W+   + G S II Y VE++++ +  W+    +  T
Sbjct: 60   PAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLCT 119

Query: 1437 --QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNITT 1493
              + ++  L+    Y+FR  A N + +S+ SE ++   V ++ T   +P  +  L++   
Sbjct: 120  FPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVA 179

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549
               E  E   I+ G P PKV+W++DG ++    +T   T   +                K
Sbjct: 180  LEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIK 239

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            C A N  G + T   + I+  P + +  + +     + G+   + A   G PPP + WY 
Sbjct: 240  CSATNRAGHISTRAKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYH 299

Query: 1609 NGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            NG  +  D+ +N  +  +  ++++I++ KR    +YTI A N  G       + V D+P+
Sbjct: 300  NGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTVTDRPA 359

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
             P   ++   + R SVT+ WK P DDGG ++  Y IE +    + W+K A   R + T  
Sbjct: 360  APGKTIVTSTLGR-SVTLAWKEPDDDGGCKIGTYIIEYYRIGWDVWLK-AVTCRQI-TAT 416

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
            +  L E  EY FRV A+NP G S+  E   I+
Sbjct: 417  LNDLIEGSEYRFRVKAENPYGVSDPSEESDII 448



 Score =  112 bits (269), Expect = 1e-22
 Identities = 69/249 (27%), Positives = 113/249 (45%), Gaps = 7/249 (2%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284
            V+W+K    I  + +  + +D  K  LII++ + DD+ E  C   +     +T+ K+ ++
Sbjct: 199  VSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIKCSATNRAGHISTRAKL-MI 257

Query: 1285 EFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDS 1340
            E PP +     YE     ++G  + L       P P+  W  N +II    +H   SI  
Sbjct: 258  EAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITD 317

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
                L I+  +  D G Y +R  N  G       VT+ D+P+ PGK  +      S+ + 
Sbjct: 318  NETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTVTDRPAAPGKTIVTSTLGRSVTLA 377

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            W EP++ G   I  Y++EY  I    W+      +   ++ +L   S YRFR  A N   
Sbjct: 378  WKEPDDDGGCKIGTYIIEYYRIGWDVWLKAVTCRQITATLNDLIEGSEYRFRVKAENPYG 437

Query: 1461 ISDASETTE 1469
            +SD SE ++
Sbjct: 438  VSDPSEESD 446



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 56/229 (24%), Positives = 98/229 (42%), Gaps = 16/229 (6%)

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           +F+      + ++   E S P+ + ++      P+    L+  +  +GE         G 
Sbjct: 135 QFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGT 194

Query: 762 PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
           P P ++W K+   +    + + T   G   S+ I++   + DEG     A N  G   T 
Sbjct: 195 PLPKVSWFKDGFEIFSSRRTMITTDSGK--SVLIIQRTSIDDEGEIKCSATNRAGHISTR 252

Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPS 876
           A + +E P            ++++  + E+G TI+L A     P PSITWY N EII   
Sbjct: 253 AKLMIEAPPHVRLP-----RQYEDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVD 307

Query: 877 ETITQNFDG-ENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTI 923
           +    NF+   + E ++   D++  D G+Y   A N  G+      VT+
Sbjct: 308 Q--RHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTV 354



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P+ P   +V+ +  RSVTL W EP+ +GG  I  YIIE+  +    W K VT        
Sbjct: 358  PAAPGKTIVTSTLGRSVTLAWKEPDDDGGCKIGTYIIEYYRIGWDVWLKAVTCRQIT--A 415

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
             + ++ E  E  FR+ AEN  GVS P+E   +
Sbjct: 416  TLNDLIEGSEYRFRVKAENPYGVSDPSEESDI 447



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 91/409 (22%), Positives = 163/409 (39%), Gaps = 39/409 (9%)

Query: 1666 PSKPEGPVIM---REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
            P+ P  P+++    +   + V I W+    +GG  +  Y +E  +  +  W++ A V   
Sbjct: 60   PAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLCT 119

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXXXXXX 1778
                 +  L     Y FR+ AQN +G SE  E S+P+ +   +TA   P           
Sbjct: 120  FPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVA 179

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEG------KKWKXXXXXXXXXARIQKLSIN 1832
            ++ E             G+P+   KV   ++G      ++             IQ+ SI+
Sbjct: 180  LEGEQAEFEVI----YAGTPL--PKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSID 233

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
               + +  A N  G  +   +   I     +  P Q  + ++ E    ++ LK T    N
Sbjct: 234  DEGEIKCSATNRAG-HISTRAKLMIEAPPHVRLPRQYEDGLLFEQ-GETIRLKAT----N 287

Query: 1893 GGSP---ITNYII-EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            GG P   IT Y   E   V  +   + +T   ++ +  I++ K +D   + I A N +G 
Sbjct: 288  GGRPPPSITWYHNGEIIIVDQRHNFESITDNETILK--IQDAKRQDRGEYTIRAINKLG- 344

Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
                E  +  L      P+ P   +    +G ++ + +W  P+ DGG  +  Y I    +
Sbjct: 345  ----EDVASFLVTVTDRPAAPGKTIVTSTLGRSVTL-AWKEPDDDGGCKIGTYIIEYYRI 399

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
               +W++   V    +   + DL E   Y  R+ A N  G+S+P E  +
Sbjct: 400  GWDVWLKA--VTCRQITATLNDLIEGSEYRFRVKAENPYGVSDPSEESD 446



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 53/184 (28%), Positives = 77/184 (41%), Gaps = 14/184 (7%)

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           EG     E      P P ++W   G EI       +  +S      SVL I       EG
Sbjct: 181 EGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGK----SVLIIQRTSIDDEG 236

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
                A NR G  S    L I+     PP V  P +    ++  QGE++ L A   G P 
Sbjct: 237 EIKCSATNRAGHISTRAKLMIEA----PPHVRLPRQYEDGLLFEQGETIRLKATNGGRPP 292

Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
           P+ITW  N + +   +    +S  D  +I  ++  K +D G YT++A N  G    S ++
Sbjct: 293 PSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLV 352

Query: 821 TVEE 824
           TV +
Sbjct: 353 TVTD 356



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 44/178 (24%), Positives = 83/178 (46%), Gaps = 11/178 (6%)

Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
           + ++A+N+ G++E S +      T +   +  P F    ++    E    +        P
Sbjct: 136 FRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGTP 195

Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVI-TNVDSEIDSGDYKCVASNSAGKSSHG 918
           +P ++W+++  EI S   T+     G+++ ++  T++D   D G+ KC A+N AG  S  
Sbjct: 196 LPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSID---DEGEIKCSATNRAGHISTR 252

Query: 919 ARVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973
           A++ I+    V   +  +     E+G+T+ L+         S  WYHN  EI  +D R
Sbjct: 253 AKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYHN-GEIIIVDQR 309



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           S AP F   LR     +G   +FE    G P P+++WF+    I  S+   M   D   +
Sbjct: 165 SSAPRFDLDLRDCVALEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRR-TMITTDSGKS 223

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            L+I+    +D G   C A N AG  S+  +L++EAP
Sbjct: 224 VLIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAP 260



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 3/100 (3%)

Query: 1965 VPSPPTAPLEI---RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
            +P+PP  P+ I        ++V   W     +GG+ ++GY++  R +    W+    V  
Sbjct: 59   LPAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLC 118

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
               +  +  L     Y  RI A+N +GLSEP E  +P  V
Sbjct: 119  TFPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSV 158



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 50/183 (27%), Positives = 73/183 (39%), Gaps = 17/183 (9%)

Query: 1120 KGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
            +G +A FE+ +  G  L  V WFKDG EI  S    +T D  K  L I    +DD GE  
Sbjct: 181  EGEQAEFEV-IYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIK 239

Query: 1178 C----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYK 1231
            C      G+    A L +E  P +    +  + +L        L           +TWY 
Sbjct: 240  CSATNRAGHISTRAKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYH 299

Query: 1232 KKSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
               +I  +    F  I+D  +  L I+     D+ EYT      ++  KL  +V  F   
Sbjct: 300  NGEIIIVDQRHNFESITD-NETILKIQDAKRQDRGEYT-----IRAINKLGEDVASFLVT 353

Query: 1290 IVD 1292
            + D
Sbjct: 354  VTD 356



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 12/192 (6%)

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDG-EIIKP 1058
            + D  + T+     + P F   L+D    E + A  EV    +    V W +DG EI   
Sbjct: 152  LSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSS 211

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEI-ITRLQ 1114
            ++     +    +  L I+ TS+ DEGE  C   + +    T    ++E PP + + R  
Sbjct: 212  RRTMITTDSGKSV--LIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAPPHVRLPRQY 269

Query: 1115 NQKVNKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDL 1170
               +      T  ++ T G      + W+ +G  I     H   +I   +  LKI D   
Sbjct: 270  EDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKR 329

Query: 1171 DDAGEYSCEVGN 1182
             D GEY+    N
Sbjct: 330  QDRGEYTIRAIN 341



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 10/151 (6%)

Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-----E 647
           S  + LI++    D   E+              A ++   PP   + P+ QY D     +
Sbjct: 220 SGKSVLIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAPPHV-RLPR-QYEDGLLFEQ 277

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G  I L+      P P I W   GE I+ D+  +    +D     ++LKI + K+   G 
Sbjct: 278 GETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNE---TILKIQDAKRQDRGE 334

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
           YT+ A+N+ GE     ++ +      P + I
Sbjct: 335 YTIRAINKLGEDVASFLVTVTDRPAAPGKTI 365



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/67 (31%), Positives = 29/67 (43%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T++ +    G P P ITW+    II   Q        DN   L I++   +D G +T 
Sbjct: 278 GETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTI 337

Query: 584 VAKNAAG 590
            A N  G
Sbjct: 338 RAINKLG 344


>UniRef50_UPI0000ECA094 Cluster: eEF1A2 binding protein; n=3; Gallus
            gallus|Rep: eEF1A2 binding protein - Gallus gallus
          Length = 843

 Score =  174 bits (424), Expect = 2e-41
 Identities = 116/480 (24%), Positives = 201/480 (41%), Gaps = 10/480 (2%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
            V K L ++     E  EL+C          TW++DG KL +       +           
Sbjct: 51   VSKHLNDVRVLKGEPTELSCAVNRHDLTG-TWFKDGLKLTSMDGVSLEKEGLVHKLVISK 109

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPV---ITISN-EDIKQKHKVGDEWLVTAVIEGI 1599
                +      + G+++T   + ++  P    I + N   +    K G++ ++    EG 
Sbjct: 110  VEDIHAGKYRFEAGDIKTEASIFVEDPPQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGR 169

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
             P    W K+  +L +D    +   +  +++ I   +R     Y +   N +G   +++ 
Sbjct: 170  LPVRATWLKDKIELGDDSRVRVDKTDTFTMLSISNAERKDCGDYKVRLKNDSGILDIDLK 229

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
            ++V DKP  P GP+ + E S   VTI+W PP DDGG  +  Y IEK +   + W+ V + 
Sbjct: 230  VEVIDKPQPPAGPMKIVESSANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGET 289

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
             R   T+   K+ ++  Y FRV A N  G S+ALES+ +V  T                +
Sbjct: 290  PRSCTTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVV--TISKGSPGAPDPPEIIGV 347

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXXARIQKLSINTTYQ 1836
              +++ I+W    + G S I  Y V+ ++ G   W             +I  L     Y+
Sbjct: 348  SKDTITISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYE 407

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            F + A N  G          +    + TPP + R+  ++ + + SVTL W  PE+  GS 
Sbjct: 408  FCVAAVNASGIGDMSAPSQSVFARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSA 467

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            +  Y +E ++    SWTK          + ++ ++ K     R+ A N  G    TE ++
Sbjct: 468  VEGYNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEA 527



 Score =  138 bits (333), Expect = 2e-30
 Identities = 160/669 (23%), Positives = 258/669 (38%), Gaps = 39/669 (5%)

Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            L + +V KG        + + D    WFKDG ++   + + L  +G   KL I   +   
Sbjct: 55   LNDVRVLKGEPTELSCAVNRHDLTGTWFKDGLKLTSMDGVSLEKEGLVHKLVISKVEDIH 114

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP--ANTDAYLTVEIPDE---TLDV 1227
            AG+Y  E G+ K  A + VE+P     + L     VP  A     + ++IP E    +  
Sbjct: 115  AGKYRFEAGDIKTEASIFVEDPPQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGRLPVRA 174

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVE 1285
            TW K K  + D  +  +        L I      D  +Y   L +        LKVEV++
Sbjct: 175  TWLKDKIELGDDSRVRVDKTDTFTMLSISNAERKDCGDYKVRLKNDSGILDIDLKVEVID 234

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS- 1342
             P       +       +DVT+  +       +P   +I+  + + K          +S 
Sbjct: 235  KPQPPAGPMKIVE-SSANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSC 293

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADV--EMNVTILDKPSP--PGKPNILEIDSSSIN 1398
             + T  KVE   +  +++R  N  G +D      V  + K SP  P  P I+ +   +I 
Sbjct: 294  TTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIGVSKDTIT 353

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAV 1456
            I W  P   G+S I  Y+V+ +++ +  W+ V +  +   +  I +LK    Y F   AV
Sbjct: 354  ISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYEFCVAAV 413

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT-----CIFGGVPQP 1511
            N   I D S  ++   V        P   + LK +T   N  + LT        G   + 
Sbjct: 414  NASGIGDMSAPSQ--SVFARDSTTPPGKVRDLK-MTINDNTSVTLTWNAPEAKEGSAVEG 470

Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQQ 1569
                 R    L   K                     Y  +  A ND G  E + +    +
Sbjct: 471  YNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEACTE 530

Query: 1570 KPVITISNEDIKQKH-------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
                 +S   I  K        K G+   V    E  P   + W K+G  L +     I+
Sbjct: 531  AVPRVVSPRFIIDKRVKNFLVIKAGNTIRVDIPYEAPPDSVLTWLKDGVPLPS--RAKIS 588

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIE-ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
            T++ TS + IK  + + S  YT+E  S T    +    ++V D P +P GP+ +RE    
Sbjct: 589  TQDDTSQLLIKAAQFTDSGIYTVELTSGTGKRETFSFQVQVTDIP-QPPGPIELRENVPN 647

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
             VT+ W+P   +       Y + K E     W  + D+      +   K+    +Y FRV
Sbjct: 648  IVTVTWEPSTSEKWESNLFYTVLKRESRKGLWHVIGDLIY-TNKFTYTKVIPGRDYYFRV 706

Query: 1742 IAQNPVGFS 1750
            +A+N +G S
Sbjct: 707  VAKNHLGSS 715



 Score =  120 bits (290), Expect = 3e-25
 Identities = 107/468 (22%), Positives = 196/468 (41%), Gaps = 25/468 (5%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W+K+G KL +    ++  +     + I +++  H+ KY  EA    G    E ++ V D 
Sbjct: 81   WFKDGLKLTSMDGVSLEKEGLVHKLVISKVEDIHAGKYRFEA----GDIKTEASIFVEDP 136

Query: 1666 PSKPE----GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            P   E        +  +++    +  K P +        +  +K E  ++  ++V   D 
Sbjct: 137  PQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGRLPVRATWLKDKIELGDDSRVRVDKTDT 196

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID 1780
                       ++C   ++V  +N  G  +      I +K   +D P             
Sbjct: 197  FTMLSISNAERKDCGD-YKVRLKNDSGILD------IDLKVEVIDKPQPPAGPMKIVESS 249

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQF 1837
               V I W P + +GG P+ +Y +E +Q GK  W                K+  + +Y F
Sbjct: 250  ANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSCTTFTTSKVEQDMSYYF 309

Query: 1838 RIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            R+ A N  GTS    SD+ +TI K +   P  P    VS+ T   +T+ W  P   G S 
Sbjct: 310  RVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIGVSKDT---ITISWKTPRRAGSSR 366

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQ 1955
            I+ YI++ + +   +W  + +V  +  +  I ++K+  +  F ++A N  G+  +   SQ
Sbjct: 367  ISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYEFCVAAVNASGIGDMSAPSQ 426

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
            SV   + +T P      L++ +  +  V  +W  PE   G+ + GYN+ +R      W +
Sbjct: 427  SV-FARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSAVEGYNVEMRSSNNLSWTK 485

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
                 + T  + ++ L    TY +R+ A N+ G  E  E +   + +P
Sbjct: 486  CNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEACTEAVP 533



 Score =   99 bits (238), Expect = 7e-19
 Identities = 100/452 (22%), Positives = 186/452 (41%), Gaps = 27/452 (5%)

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREI 1678
            T    +     ++++  S  + + A N  GTS    S EV       P  P+ P I+  +
Sbjct: 289  TPRSCTTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIG-V 347

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            S++++TI WK P   G   ++ Y ++K +  +  W+ V  V    +   I  L +  +Y 
Sbjct: 348  SKDTITISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYE 407

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
            F V A N  G  +       V       P            DN SV +TW   E   GS 
Sbjct: 408  FCVAAVNASGIGDMSAPSQSVFARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSA 467

Query: 1799 IIDYKVEIKQEGK-KWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            +  Y VE++      W             +++ L    TY  R+ A N+ G     T  +
Sbjct: 468  VEGYNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPG-EATELE 526

Query: 1856 KIT--IGKTLTP----PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
              T  + + ++P      + +NF+V ++ +   T++   P       +  ++ +   +  
Sbjct: 527  ACTEAVPRVVSPRFIIDKRVKNFLVIKAGN---TIRVDIPYEAPPDSVLTWLKDGVPLPS 583

Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969
            ++  KI T   +  +  I+  +  D  I+ +   +  G     E+ S +++    +P PP
Sbjct: 584  RA--KISTQDDT-SQLLIKAAQFTDSGIYTVELTSGTG---KRETFSFQVQV-TDIPQPP 636

Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029
              P+E+R    NIV  +W     +     L Y +  R+  K +W  +G + + T KF   
Sbjct: 637  -GPIELRENVPNIVTVTWEPSTSEKWESNLFYTVLKRESRKGLWHVIGDL-IYTNKFTYT 694

Query: 2030 DLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +     Y  R+ A+N +G S P ++ +P+++
Sbjct: 695  KVIPGRDYYFRVVAKNHLGSSCPSDTVQPWRI 726



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 18/240 (7%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            IK G+ + + + Y+A P     W+ +   +      K S    ++ L IK  + TD+GIY
Sbjct: 552  IKAGNTIRVDIPYEAPPDSVLTWLKDG--VPLPSRAKISTQDDTSQLLIKAAQFTDSGIY 609

Query: 1359 KLRLENNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             + L +  G  +     V + D P PPG   + E   + + + W+   +    + ++Y V
Sbjct: 610  TVELTSGTGKRETFSFQVQVTDIPQPPGPIELRENVPNIVTVTWEPSTSEKWESNLFYTV 669

Query: 1418 EYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
              +E     W  + ++  T + +   +     Y FR  A N +  S  S+T + +++ K 
Sbjct: 670  LKRESRKGLWHVIGDLIYTNKFTYTKVIPGRDYYFRVVAKNHLGSSCPSDTVQPWRIRKP 729

Query: 1477 --------------TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                           + Q P    PLK        +  ++C  GG P PKVTWY+DGK L
Sbjct: 730  KADIQVRPQRYKGVNQNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDL 789



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 7/149 (4%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I N + KD   +++  +N  G+ L  + +   ++K    P PP  P++I    +N V   
Sbjct: 202  ISNAERKDCGDYKVRLKNDSGI-LDIDLKVEVIDK----PQPPAGPMKIVESSANDVTIQ 256

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ DGG P+  Y I  + V K+ W+ VG+   +   F    + ++ +Y  R+ A N 
Sbjct: 257  WNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSCTTFTTSKVEQDMSYYFRVRAVNA 316

Query: 2047 IGLSEPLESDEPFKVIPGEGSHADEEPGE 2075
             G S+ LESDE   +   +GS    +P E
Sbjct: 317  EGTSDALESDEVVTI--SKGSPGAPDPPE 343



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 4/96 (4%)

Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTH 787
           + +PP+ + PLK  +V  G    +S  V G+P P +TW K+ K +   P+    +D    
Sbjct: 745 QNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVC 804

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           S+ IL   K  DEG YT++A N  G A + A +T++
Sbjct: 805 SLVILGVSKA-DEGDYTVEATNESGRAFSRASLTIK 839



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           Q+  P F+  L+P     GS  +  C V G+P P++TW++    +  +  +    +D  V
Sbjct: 745 QNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSY-FGTNDFGV 803

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +LVI  V   D G +T  A N +G A S   L ++
Sbjct: 804 CSLVILGVSKADEGDYTVEATNESGRAFSRASLTIK 839



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 23/76 (30%), Positives = 39/76 (51%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E  ++  + G PPP+V WYK+G  L N+  Y  T       + I  + ++    YT+E
Sbjct: 763  GSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVCSLVILGVSKADEGDYTVE 822

Query: 1647 ASNTAGTSSVEVTLKV 1662
            A+N +G +    +L +
Sbjct: 823  ATNESGRAFSRASLTI 838



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
           +PP F+   +   V      ++   V  +P P +TWY++ + +S + +     D     L
Sbjct: 747 QPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVCSL 806

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           VI  V S+ D GDY   A+N +G++   A +TI
Sbjct: 807 VILGV-SKADEGDYTVEATNESGRAFSRASLTI 838



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F    K   V  GS+  + C +   P P + W   G+++    N S    +D  + C
Sbjct: 748 PPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDL--SNNPSYFGTNDFGV-C 804

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
           S L I  V K  EG YTV A N  G A     L IK
Sbjct: 805 S-LVILGVSKADEGDYTVEATNESGRAFSRASLTIK 839



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 17/73 (23%), Positives = 35/73 (47%)

Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
           ++++ G ++ +       P   +TW K+  P+ +    S  D  S  ++K  +  D G+Y
Sbjct: 550 LVIKAGNTIRVDIPYEAPPDSVLTWLKDGVPLPSRAKISTQDDTSQLLIKAAQFTDSGIY 609

Query: 804 TLKAENSEGIAET 816
           T++  +  G  ET
Sbjct: 610 TVELTSGTGKRET 622


>UniRef50_Q8T104 Cluster: Projectin-like protein; n=1; Bombyx
            mori|Rep: Projectin-like protein - Bombyx mori (Silk
            moth)
          Length = 1072

 Score =  174 bits (424), Expect = 2e-41
 Identities = 109/397 (27%), Positives = 187/397 (47%), Gaps = 16/397 (4%)

Query: 1377 ILDKPSPPGKPNILEI----DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
            +  +P+PPGKP I+ I    + ++I + W    + G + +  Y VE   + +TEWI    
Sbjct: 52   VTGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAP 111

Query: 1433 --ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLK 1489
              + + +  +  L+    Y+FR  A+N+V  S+ SE ++   V  +   Q P V  K L+
Sbjct: 112  PIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 171

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXX 1545
            ++T   N+ +E    F G+P P + W++D  ++    +TA  T E+              
Sbjct: 172  DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 231

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               KC A N  G   T   + ++  P +    + +    +++ +   +   I G P P +
Sbjct: 232  GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 291

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W  +G+ +  D    I+   K SV++I   KRS   +Y I+A N  G  +    + V  
Sbjct: 292  EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 351

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             P  P    + R++ + SVT++W+PP DDGG ++  Y +E +    N W+K A   R   
Sbjct: 352  PPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTN 409

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVI 1760
               +  L E  EY FR+ A++P G S  + ES P+ I
Sbjct: 410  V-TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 445



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 58/259 (22%), Positives = 102/259 (39%), Gaps = 8/259 (3%)

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            IP  T  + W+K    I  + +  + +D     L+  +    D+ E  C   +       
Sbjct: 190  IPSPT--IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 247

Query: 1280 KVEV-VEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            K  + +E  PK+  Y R+Y      +    + L       P P  EW  +   I      
Sbjct: 248  KARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 306

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            + SI  K + L I   + +D G Y+++ +N  G       VT+   P PP   ++     
Sbjct: 307  EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 366

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
             S+ + W+ P + G   +  Y+VEY       W+      KT  ++ +L   S Y+FR  
Sbjct: 367  KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIK 426

Query: 1455 AVNEVDISDASETTEYYKV 1473
            A +   +S  S  +   ++
Sbjct: 427  AESPYGMSAPSSESSPVRI 445



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 43/129 (33%), Positives = 64/129 (49%), Gaps = 9/129 (6%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            +++I A+N IG     T+   +T+     PP  PRN  V+    +SVTL W  P  +GG 
Sbjct: 329  EYQIQAKNIIGED---TAAFLVTV---TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 382

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954
             + NYI+E+       W K +T         + ++ E  E  FRI AE+  G+S P +ES
Sbjct: 383  KVGNYIVEYYRTGWNVWLKAIT--SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 440

Query: 1955 QSVRLEKHA 1963
              VR+   A
Sbjct: 441  SPVRIPGRA 449



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 10/254 (3%)

Query: 789  ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            +T L+P       V  L        +E S V+TV      + EPP+FI R +++T  E  
Sbjct: 121  LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSD-RASQEPPVFIKRLEDVTALEND 179

Query: 849  TIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
             ++     +  P P+I W++++ EI S   T     +  ++ L    + S  D G+ KC 
Sbjct: 180  KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS--DEGEIKCT 237

Query: 908  ASNSAGKSSHGARVTID-VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNK 964
            A+N  G +   AR+ ++   K+ + +  +     E  +T+ L+       T + +W H+ 
Sbjct: 238  ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 297

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIR 1021
              I   D  EI    +            D G  +   K+   ++T+  LV     P+  R
Sbjct: 298  HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 357

Query: 1022 KLQDFEVKEKDVAI 1035
             +      +K V +
Sbjct: 358  NVSVTRQVDKSVTL 371



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 50/198 (25%), Positives = 76/198 (38%), Gaps = 9/198 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F K+ +     E   +        IP P IAW     EI      ++  +       
Sbjct: 163 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES----T 218

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGES 751
           SVL    +    EG     A NR G A     L ++   K   P+  E    ++    E+
Sbjct: 219 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE--DGLLYEINET 276

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809
           + L   +VG P PTI W  +  P+          T   ++LK    K  D G Y ++A+N
Sbjct: 277 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 336

Query: 810 SEGIAETSAVITVEEPTE 827
             G    + ++TV  P +
Sbjct: 337 IIGEDTAAFLVTVTAPPD 354



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 4/114 (3%)

Query: 489 NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
           +E  D L V     S+E    P+F+++L      +   V+F     G P P I WF+   
Sbjct: 146 SELSDVLTVSSDRASQEP---PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 202

Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            I  S+   +   D++ + L+  ++ P D G   C A N  G A +   L +EA
Sbjct: 203 EIFSSRRTAIT-TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 255



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 58/238 (24%), Positives = 99/238 (41%), Gaps = 16/238 (6%)

Query: 695 LKITNVKKFQEGTYTVVAVNREGEAS---LPIVLKIKT--GEKEPPQVIEPLKSMIVRQG 749
           L +T ++   +  + V A+N  G ++   L  VL + +    +EPP  I+ L+ +   + 
Sbjct: 119 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 178

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
           + V       G P PTI W K++  + +    +     S ++L   ++   DEG     A
Sbjct: 179 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 238

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSIT 865
            N  G A T A + +E      A P L   R  E  +  +   TI L   +   P P+I 
Sbjct: 239 TNRGGHAVTKARLCLE------AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 292

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           W  +   I   + I  +   +   L I +     D G+Y+  A N  G+ +    VT+
Sbjct: 293 WRHDGHPIITDDRIEISITPKFSVLKIHSA-KRSDRGEYQIQAKNIIGEDTAAFLVTV 349



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 6/111 (5%)

Query: 1966 PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
            P+PP  P  I ++     N +   W     DGGAPL GY +    +  T W+      V 
Sbjct: 56   PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 115

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
              +  +  L   H Y  R+ A N++G S   E  +   V+      A +EP
Sbjct: 116  RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD---VLTVSSDRASQEP 163



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 9/144 (6%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I + K  D   ++I A+N +G     E  +  L      P PP      R V  ++ +  
Sbjct: 319  IHSAKRSDRGEYQIQAKNIIG-----EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL-D 372

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P  DGG  +  Y +        +W++   +        + DL E   Y  RI A + 
Sbjct: 373  WEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESP 430

Query: 2047 IGLSEPLESDEPFKVIPGEGSHAD 2070
             G+S P     P + IPG     D
Sbjct: 431  YGMSAPSSESSPVR-IPGRAIDMD 453



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 5/86 (5%)

Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
           I L+  +V  P P I W   G  I+ D+ I ++I        SVLKI + K+   G Y +
Sbjct: 277 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF----SVLKIHSAKRSDRGEYQI 332

Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQ 736
            A N  GE +   ++ + T   +PP+
Sbjct: 333 QAKNIIGEDTAAFLVTV-TAPPDPPR 357



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 1865 PPSQPRNF-VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923
            PP +P+   ++S+    ++TLKW     +GG+P+  Y +E   +    W +         
Sbjct: 58   PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 117

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
            E  +  ++   +  FR++A N VG S  +E   V
Sbjct: 118  ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDV 151



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 46/193 (23%), Positives = 74/193 (38%), Gaps = 19/193 (9%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKL 1074
            P FI++L+D    E D     V  +   +  + W +D  EI   ++     ++   +  L
Sbjct: 164  PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--L 221

Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT--- 1131
                    DEGE  C   +    A VT   L  E   +L+  +  +     +EI  T   
Sbjct: 222  LFHQILPSDEGEIKCTATNRGGHA-VTKARLCLEAAPKLRYPRQYEDG-LLYEINETIFL 279

Query: 1132 ------KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VG 1181
                  K    + W  DG  I   + I+++I  K   LKI+     D GEY  +    +G
Sbjct: 280  KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 339

Query: 1182 NSKCTAILTVEEP 1194
                  ++TV  P
Sbjct: 340  EDTAAFLVTVTAP 352


>UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB;
            n=2; Tribolium castaneum|Rep: PREDICTED: similar to
            CG33519-PB - Tribolium castaneum
          Length = 4089

 Score =  173 bits (422), Expect = 3e-41
 Identities = 216/904 (23%), Positives = 356/904 (39%), Gaps = 93/904 (10%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+   V  G    L C++ A P+ ++ W    + +   EN+ +  +     Y  V K   
Sbjct: 2061 PQNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETYRLVFKKAL 2120

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            +    EG Y VVA N  GE+S    LK  T   E P +I  L    V   + + +  +  
Sbjct: 2121 LS--DEGYYKVVAKNSLGESSSEARLKAVT---EKPTIITGLSDDQVEHTKEISVMVRAD 2175

Query: 760  GNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            G P+P I W  N KP+       + + +D    S   +      D G+Y   A N +G A
Sbjct: 2176 GLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGIYKAIAANVQGEA 2235

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            +TSA IT+ +       PP F  + +    V E   ++L A++  +P P++ WY+N E I
Sbjct: 2236 DTSARITMVQT------PPTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPI 2289

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV--EKVTFV 931
                  T       ++L I +     DSG YK V  N  G+S+    V +    ++  F+
Sbjct: 2290 DDERVKTSVLPDGTVKLNIEHARPS-DSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFL 2348

Query: 932  KHLQKSYETEEGKTVILECQT-SHTV-STKWYHN--KKEISGMDHREIIQEGRXXXXXXX 987
            K   K  +   G+T+ LE Q  +H     KW  +     +S   H E+  +G+       
Sbjct: 2349 KCF-KDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDC 2407

Query: 988  XXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE-I 1040
                 + G  +  V ++      E S  +  K T PEF+ +L    V E      EV+ +
Sbjct: 2408 AKPE-NAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAV 2466

Query: 1041 NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDESCTA 1098
                  + W R+G E+I   K+    E       L +   +   +G  Y  I  +E+  A
Sbjct: 2467 GHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEA 2526

Query: 1099 E----VTVV--------ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSE 1145
            E    +TV+        E  P  +  L++   ++G         T     +V W KDG  
Sbjct: 2527 ETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVP 2586

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFT 1199
            +  S+ I +T DGKK  L+I +    DAG YS ++ N      S+  A +       +FT
Sbjct: 2587 LSPSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFMPPHFT 2646

Query: 1200 LRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
                +   +P   DA     +      +V W K    I++++K+ +  D     L +  C
Sbjct: 2647 QTFTDLQQLPGR-DAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNC 2705

Query: 1259 TEDDQCEY--TCVLLDAKSTTKLKVEVVE--------FPPKIVDYEREYRIKRGSDVTLL 1308
            + DD   Y    +  + +      +EVV+         PP  +    +  + +G      
Sbjct: 2706 SPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFT 2765

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCG 1367
                 +P+P  EW  N + +      K   D      L I  ++  D G Y  ++ N  G
Sbjct: 2766 ACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEADLGKYSCKITNEYG 2825

Query: 1368 ----HADVEMN--------------VTILDK------PSPPGKPNIL-EIDSSSINICWD 1402
                HA++ M+               T  DK      P P   P I+ ++      + W 
Sbjct: 2826 GDICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCTLSWK 2885

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
                 G    + Y +E  E+   +W +V+  I      ++NL+    Y+FR    N+  I
Sbjct: 2886 PSIPPGPRAPVTYQLEMCELPNGDWFTVRTGIRSCTCGVRNLEPFRDYKFRVRVENKYGI 2945

Query: 1462 SDAS 1465
            SD S
Sbjct: 2946 SDPS 2949



 Score =  149 bits (362), Expect = 6e-34
 Identities = 160/687 (23%), Positives = 296/687 (43%), Gaps = 46/687 (6%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-------LPTK 781
            +G++E  + I+ ++   +  GE       +   P  T TW K++KP+ +       +  +
Sbjct: 836  SGDEERNRFIKTIRGADIEPGEKFTFEVALKSKP-DTFTWLKDDKPLDSNAIMLGRIQMR 894

Query: 782  SDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN------AEPPL 834
               D++   + + P    D G YT  A    G A  SA++ V + T E        + P 
Sbjct: 895  HSEDSYLYKLYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPE 954

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDGENIELV 891
            F+ + ++  + E   ++ + +V  +P P + ++++  I+  S   E I ++ D    EL+
Sbjct: 955  FVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELL 1014

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
            I  V    D+G+YKCVASN  G+ S  A + +  E +   K + +      G+T   + +
Sbjct: 1015 IPEVQMS-DAGEYKCVASNKWGEDSCEATLKVTTEDLH--KDMPEGEILPPGETPEFQWK 1071

Query: 952  TSHTVSTKWYHNKKEISGMDHRE---IIQEGRXXXXXXXX-XXXXDVGVIKCIVK--DQE 1005
                   +     K + G D      + Q  R               G I C  +     
Sbjct: 1072 -KDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVHG 1130

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP-KKNKY 1063
            T   LV +   P  I + ++  V     A++E+++       V W  +G+ I+   K K+
Sbjct: 1131 TVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYKF 1190

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQNQKVNK 1120
             +E       L I++    D G+Y C   +E  S TAE+T+ V+ PP++  ++++   + 
Sbjct: 1191 LYEDE-ETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPPKLRKKIEDVDAHA 1249

Query: 1121 G--NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
                +   EIE T    +V ++KDG EI+    I++  + +K  L I    L D+G YS 
Sbjct: 1250 DLLLEIPVEIEGTPRPKVV-FYKDGKEIKKDERIKVVEENEKVVLVIEKTMLKDSGSYSI 1308

Query: 1179 EVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
               N     S+   +    +P I   L   + +      +  + +E   E  +V WYK  
Sbjct: 1309 VATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIESEPEA-EVKWYKDD 1367

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVD 1292
            + I+ ++ + +  D +   L I      D   Y    ++   + +  + V V+  PKI  
Sbjct: 1368 AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDVKKAPKITK 1427

Query: 1293 YEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKV 1350
              ++  + +    VTL V  +AFP+P+ +W ++   I + K     +DS     L IK+V
Sbjct: 1428 GLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEV 1487

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTI 1377
             +  +G Y  +L N CG  +    +T+
Sbjct: 1488 NSELSGKYTCKLSNECGSTETSAKLTV 1514



 Score =  145 bits (352), Expect = 1e-32
 Identities = 239/1123 (21%), Positives = 442/1123 (39%), Gaps = 118/1123 (10%)

Query: 314  SRNIKEAAKVK-KQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQT--LEE 370
            SR I E   ++ KQ+      P +E+         + DI+E    E+E ++  +T  ++ 
Sbjct: 1675 SRTIAEKIDIEEKQIKHSTPEPIIEEPLSPNIQRGHSDILE----ESEFVENDETDKVQH 1730

Query: 371  LPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYV 430
            + +ED+P+   +  +++ +  I+EI +     +   P E   T V  R      A     
Sbjct: 1731 MKEEDLPK---VKSKRAKSIHIEEIEENELSSEPKTPIE---TEVPKRKASKAQAATVEE 1784

Query: 431  AETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE 490
             E  E +N    E    L  S  +    QK + E        Y  +++   + L K+  +
Sbjct: 1785 LEIIETLN----ETPQQLKESKFERQESQKGVRE--------YEEEQDEEMEALLKRAQK 1832

Query: 491  KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550
            +   +    +    +++   I    ++    P+   + +  +    P P+ TW      +
Sbjct: 1833 QRSLVEELPQKGELDEAKPTITSSNMKDSSRPESLDICYIVKGTSNPPPKATWTINGQEL 1892

Query: 551  KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
            KP    +M    +     +++ +  +DAG   C+ KN  G A   T ++   P  +    
Sbjct: 1893 KPDSRVRMTNKGEEFKLEIVK-LKMDDAGKIECILKNPLGEARQ-TAMLEVTPEKE---- 1946

Query: 611  MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFK 670
                             + EG+        K Q + + + +  +  ++  P PD  W   
Sbjct: 1947 ------------LRRPKLKEGL--------KDQTIQKKNTLTFKAVVIGDPVPDATWSVD 1986

Query: 671  GEEIVPD--ENISVAIESDMHMY------CS-VLKITNVKKFQEGTYTVVAVNREGEASL 721
            G E+  +  E   + +E++ H        C+  L I   ++   G YT  A N+ GE + 
Sbjct: 1987 GHELTSEAFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNS 2046

Query: 722  PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---L 778
               L +       P++  P +++ V  GE+  L  ++  NP+  + W K+++ VK    L
Sbjct: 2047 SAQLTVVLR----PEIEGP-QNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENL 2101

Query: 779  PTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836
               SD   +T+ + + K   + DEG Y + A+NS G  E+S+   ++  TE+    P  I
Sbjct: 2102 KIVSDVANETYRL-VFKKALLSDEGYYKVVAKNSLG--ESSSEARLKAVTEK----PTII 2154

Query: 837  NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITN 894
                +  V+    I ++ R    P P I W  N + I   E   I  + D +    +  +
Sbjct: 2155 TGLSDDQVEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVS 2214

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-- 952
              ++ DSG YK +A+N  G++   AR+T+     TF K L++S +  EG+ + L+ +   
Sbjct: 2215 DFNDSDSGIYKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDVIEGEPLELKAKING 2274

Query: 953  SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTML 1010
            S   +  WY N + I     +  +                D G  K ++++   E++ + 
Sbjct: 2275 SPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLC 2334

Query: 1011 VV----KETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKN-KYD 1064
             V    K   P+F++  +D ++   +   LE ++ +    +V W +DG  ++   N  ++
Sbjct: 2335 AVAVQQKPQRPKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFE 2394

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTVVELP--PEIITRLQNQKV 1118
                G +  L +      + G+Y   +     D    A V + + P  PE + RL  Q V
Sbjct: 2395 VHPDGKV-ALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTV 2453

Query: 1119 NKGNKATFEIELTKGDA-LVRWFKDGSEIQFSN-HIQLT--IDGKKQKLKIYDCDLDDAG 1174
             +G    FE++     A  + W ++G+E+   N H++++   DG    L        D  
Sbjct: 2454 VEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGL 2513

Query: 1175 EYSC----EVGNSKCTAILTVEEPSINFTL--RLPEFIL----VPANTDAYLTVEIP--- 1221
             Y      E G ++ +A LTV  P+ N       P F+     V A+    L +  P   
Sbjct: 2514 TYRAIAINEAGEAETSAPLTV-IPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTA 2572

Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKSTT 1277
            +    V W K    +  +++  +  D KK  L I      D   Y+      L +  S  
Sbjct: 2573 NPVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEA 2632

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
               V  V  PP       + +   G D          PQP   W  +   IK+       
Sbjct: 2633 NAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIK 2692

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
             D     L +      DA +Y+ R  N  G      ++ ++D+
Sbjct: 2693 RDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQ 2735



 Score =  140 bits (340), Expect = 3e-31
 Identities = 129/547 (23%), Positives = 223/547 (40%), Gaps = 34/547 (6%)

Query: 663  PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722
            P+  W   G    PDE   V +  D      V +  +V+    G YT VA    G  S  
Sbjct: 1066 PEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQ--HVRAEDVGLYTCVAQTSRGHISCS 1123

Query: 723  IVLKIK------TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776
              L +         E E P +I   ++ +V  G S ++  QV G P+P + W    KP++
Sbjct: 1124 AELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIE 1183

Query: 777  A----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
            A         D +T S+ ++K  + +D G Y   AEN  G       +TV+        P
Sbjct: 1184 AGGKYKFLYEDEETMSL-VIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVK-------TP 1235

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P    + +++       +++   +   P P + +Y++ + I   E I    + E + LVI
Sbjct: 1236 PKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVI 1295

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQ 951
                 + DSG Y  VA+N   + S    + +  + K+       K    EE   + ++ +
Sbjct: 1296 EKTMLK-DSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIE 1354

Query: 952  TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG--VIKCI-VKDQETST 1008
            +      KWY +  EI   DH  I ++G             D     +K + +       
Sbjct: 1355 SEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDD 1414

Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAI-LEVEINS-ETADVVWERDGEIIKPKKNKYDFE 1066
            + V  +  P+  + LQD  V E D  + L+V++ +     V W  D   I   K ++   
Sbjct: 1415 IRVDVKKAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRV 1474

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNK 1123
                  KL I+  +    G+Y+C L +E  + E +    V   P II +L++  V +G  
Sbjct: 1475 DSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGAT 1534

Query: 1124 ATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQK---LKIYDCDLDDAGEYSCE 1179
               E+E+       V+W ++G E+     I+++ D ++ +   L +     ++ GEY   
Sbjct: 1535 LHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVV 1594

Query: 1180 VGNSKCT 1186
            V NS  T
Sbjct: 1595 VTNSMGT 1601



 Score =  140 bits (338), Expect = 5e-31
 Identities = 128/468 (27%), Positives = 208/468 (44%), Gaps = 62/468 (13%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
            + VEK  P     GS +  E QV+G+P+PQ+ W  +   I+    ++  Y+D+   +LVI
Sbjct: 1144 LIVEKRNPVVNAGGSAM-IELQVKGFPKPQVKWTHEGKPIEAGGKYKFLYEDEETMSLVI 1202

Query: 571  REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630
            ++V  EDAG + C A+N  G  ++   L V+ P                      AD+L 
Sbjct: 1203 KDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTP---------PKLRKKIEDVDAHADLLL 1253

Query: 631  GIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
             IP     + +PK  +  +G +I  + R+  + E              +E + + IE  M
Sbjct: 1254 EIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEE--------------NEKVVLVIEKTM 1299

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVR 747
                  LK         G+Y++VA N   + S    L + T     P+++E L K  IV 
Sbjct: 1300 ------LK-------DSGSYSIVATNELAQISEFFNLHVHT----KPKILEKLGKDKIVS 1342

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYT 804
            Q E   L  ++   P   + W K++  +K+      K DG+T+ + I       D   Y 
Sbjct: 1343 QEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKI-TGAVTTDAARYK 1401

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863
            +KA N  G  E    + V+       + P      Q++TV E    + L  +V   P PS
Sbjct: 1402 VKAVNIHGSVEDDIRVDVK-------KAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPS 1454

Query: 864  ITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            + WY +   I+ ++T     D ++ ++LVI  V+SE+ SG Y C  SN  G +   A++T
Sbjct: 1455 VKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSEL-SGKYTCKLSNECGSTETSAKLT 1513

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEIS 968
            ++      +K L K    EEG T+ LE +     T + KW  N +E+S
Sbjct: 1514 VNCAP-RIIKQL-KDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVS 1559



 Score =  137 bits (332), Expect = 3e-30
 Identities = 173/727 (23%), Positives = 283/727 (38%), Gaps = 54/727 (7%)

Query: 586  KNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            K  +  A+ T  L+ + A LSD G    V                    PT         
Sbjct: 2102 KIVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQ 2161

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V+   +I +  R   +P+P I WL  G+ IV DE   +   +D  +  S L +++     
Sbjct: 2162 VEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQV-TSTLTVSDFNDSD 2220

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPR 763
             G Y  +A N +GEA     +   T  + PP   + L +S  V +GE + L A++ G+P+
Sbjct: 2221 SGIYKAIAANVQGEADTSARI---TMVQTPPTFGKKLERSEDVIEGEPLELKAKINGSPK 2277

Query: 764  PTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            PT+ W KN +P+  + + T    D      ++  +  D G Y L  +N  G +     + 
Sbjct: 2278 PTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVA 2337

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V++  +     P F+  F+++ +    T++L A+V  +P P + W ++   +  S  I  
Sbjct: 2338 VQQKPQR----PKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHF 2393

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE--KVTFVKHLQKSYE 939
                +    +I +     ++G Y+   SN  G +   A V I+ +  K  F+  L     
Sbjct: 2394 EVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQ-T 2452

Query: 940  TEEGKTVILECQTSHTVSTK--WYHNKKE-ISGMDHREI--IQEGRXXXXXXXXXXXXDV 994
              EG  V  E +     + K  W  N  E IS   H +I  + +G             D 
Sbjct: 2453 VVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDG 2512

Query: 995  GVIKCIVKDQ----ETSTMLVV--------KETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
               + I  ++    ETS  L V         E  P F+  L+D    E    +L     +
Sbjct: 2513 LTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTA 2572

Query: 1043 ETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCT 1097
                +V W +DG  + P  ++      G    L I N    D G YS      L +ES  
Sbjct: 2573 NPVPMVEWSKDGVPLSP-SDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSE 2631

Query: 1098 AEVTV--VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQL 1154
            A   V  V +PP       + +   G  A F   ++      V W KDG  I+ S+   +
Sbjct: 2632 ANAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHI 2691

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAIL-TVEEPSINFTLRLPEFILVP 1209
              DG    L + +C  DDA  Y        G   CTA L  V++      +  P F+   
Sbjct: 2692 KRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRI 2751

Query: 1210 ANTDAY--LTVEIPD-----ETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTED 1261
             +T+ +  +T +           +V WY     +  + +  + +D      LII    E 
Sbjct: 2752 GDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEA 2811

Query: 1262 DQCEYTC 1268
            D  +Y+C
Sbjct: 2812 DLGKYSC 2818



 Score =  134 bits (324), Expect = 3e-29
 Identities = 159/701 (22%), Positives = 293/701 (41%), Gaps = 79/701 (11%)

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK-----KNKYDFEKRGHIRK 1073
            FI+ ++  +++  +    EV + S+     W +D + +        + +    +  ++ K
Sbjct: 844  FIKTIRGADIEPGEKFTFEVALKSKPDTFTWLKDDKPLDSNAIMLGRIQMRHSEDSYLYK 903

Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE------------IITRLQNQK 1117
            LYI  T   D G Y+ +        +C+A + V ++ PE             + +L++ +
Sbjct: 904  LYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKDTE 963

Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ---KLKIYDCDLDD 1172
            + +     F +++ +GD    V +FKDG  ++ S+  ++  +   +   +L I +  + D
Sbjct: 964  LAENTYLRFMVKV-RGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMSD 1022

Query: 1173 AGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228
            AGEY C   N      C A L V    ++  +  PE  ++P           P ET +  
Sbjct: 1023 AGEYKCVASNKWGEDSCEATLKVTTEDLHKDM--PEGEILP-----------PGETPEFQ 1069

Query: 1229 WYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS----TTKLKV- 1281
            W K  +  E  E+F ++   D     L+ +    +D   YTCV   ++     + +L V 
Sbjct: 1070 WKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVH 1129

Query: 1282 ----EVVEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHT 1334
                ++V  P  P ++  +R   +  G    + +  + FP+P  +W    K I+   K+ 
Sbjct: 1130 GTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYK 1189

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
                D ++ SL IK V+  DAG Y    EN  G    EM +T+  K  P  +  I ++D+
Sbjct: 1190 FLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTV--KTPPKLRKKIEDVDA 1247

Query: 1395 SSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYR 1450
             + ++  + P   E T    +++Y  + +EI   E I  V+   K    I+      S  
Sbjct: 1248 HA-DLLLEIPVEIEGTPRPKVVFY-KDGKEIKKDERIKVVEENEKVVLVIEKTMLKDSGS 1305

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +   A NE+     ++ +E++ +   TK     +EK  K+      E  EL       P+
Sbjct: 1306 YSIVATNEL-----AQISEFFNLHVHTK--PKILEKLGKDKIVSQEEKFELRVKIESEPE 1358

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXX----XXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
             +V WY+D  ++K++      +                   YK  A N HG VE    V 
Sbjct: 1359 AEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVD 1418

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKE 1625
            +++ P IT   +D+   ++   +  +   +E  P P V WY +  ++ E   E+     +
Sbjct: 1419 VKKAPKITKGLQDM-TVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSD 1477

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                + IKE+    S KYT + SN  G++     L V   P
Sbjct: 1478 DGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAP 1518



 Score =  130 bits (315), Expect = 3e-28
 Identities = 170/793 (21%), Positives = 327/793 (41%), Gaps = 77/793 (9%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YC 692
            F K  +   ++ G     E  L + P+    WL K ++ +    I +      H    Y 
Sbjct: 844  FIKTIRGADIEPGEKFTFEVALKSKPDT-FTWL-KDDKPLDSNAIMLGRIQMRHSEDSYL 901

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVL---------KIKTGEKEPPQVIEPLKS 743
              L I        G YT +A    G A+   +L         +++  + + P+ +  LK 
Sbjct: 902  YKLYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKD 961

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSITILKPK-KVK 798
              + +   +    +V G+P P + + K+   V+        +   D     +L P+ ++ 
Sbjct: 962  TELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMS 1021

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEE-NAEPPLFINRFQEITVKEKGTIKLVARVT 857
            D G Y   A N  G  E S   T++  TE+ + + P             +G I     + 
Sbjct: 1022 DAGEYKCVASNKWG--EDSCEATLKVTTEDLHKDMP-------------EGEI-----LP 1061

Query: 858  RNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
                P   W ++     P E   +    D +++ LV  +V +E D G Y CVA  S G  
Sbjct: 1062 PGETPEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAE-DVGLYTCVAQTSRGHI 1120

Query: 916  SHGARVTI---------DVEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKWYHNKK 965
            S  A +T+         + EK   +   +       G  +I L+ +       KW H  K
Sbjct: 1121 SCSAELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGK 1180

Query: 966  EI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIR 1021
             I +G  ++ + ++              D G   C  +++   +T+ M +  +T P+  +
Sbjct: 1181 PIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPPKLRK 1240

Query: 1022 KLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
            K++D +     +  + VEI  +    VV+ +DG+ IK  +     E+   +  L I  T 
Sbjct: 1241 KIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKV-VLVIEKTM 1299

Query: 1081 VHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQK-VNKGNKATFEIEL-TKGDA 1135
            + D G YS +  +E           V   P+I+ +L   K V++  K    +++ ++ +A
Sbjct: 1300 LKDSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIESEPEA 1359

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA---ILTVE 1192
             V+W+KD +EI+ S+H  +  DG+   LKI      DA  Y  +  N   +    I    
Sbjct: 1360 EVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDV 1419

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTE-KFTLISDV 1248
            + +   T  L +  +     D  +T+++  E      V WY  +  I +T+ +FT +   
Sbjct: 1420 KKAPKITKGLQDMTV--NEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSD 1477

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTL 1307
                L+I++   +   +YTC L +   +T+   ++ V   P+I+   ++  ++ G+ + L
Sbjct: 1478 DGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHL 1537

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS---KSASLTIKKVENTDAGIYKLRLEN 1364
             V+ +  P P  +W+ N + +      K S D+   ++ +L +  ++  + G Y++ + N
Sbjct: 1538 EVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTN 1597

Query: 1365 NCGHADVEMNVTI 1377
            + G    +  VT+
Sbjct: 1598 SMGTVSSKSYVTV 1610



 Score =  130 bits (313), Expect = 5e-28
 Identities = 134/572 (23%), Positives = 237/572 (41%), Gaps = 49/572 (8%)

Query: 539  PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
            P+  W +  A  +P + F++   DD++   LV + V  ED G +TCVA+ + G  S + E
Sbjct: 1066 PEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAE 1125

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            L V      HG+   +              + E   P    + +   V+ G   ++E ++
Sbjct: 1126 LTV------HGTVNQL--------------VREPEKPVLIVEKRNPVVNAGGSAMIELQV 1165

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
               P+P + W  +G+ I          E +  M    L I +V+K   G Y   A N  G
Sbjct: 1166 KGFPKPQVKWTHEGKPIEAGGKYKFLYEDEETM---SLVIKDVQKEDAGKYLCTAENEIG 1222

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
              +  + L +KT    PP++ + ++ +       + +  ++ G PRP + + K+ K +K 
Sbjct: 1223 SDTAEMTLTVKT----PPKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKK 1278

Query: 778  LPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
                   + +   + +++   +KD G Y++ A N   +A+ S    +   T    +P + 
Sbjct: 1279 DERIKVVEENEKVVLVIEKTMLKDSGSYSIVATNE--LAQISEFFNLHVHT----KPKIL 1332

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
                ++  V ++   +L  ++   P   + WY+++  I  S+      DGE   L IT  
Sbjct: 1333 EKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGA 1392

Query: 896  DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVILECQTS- 953
             +  D+  YK  A N  G      RV  DV+K     K LQ     E  K V L+ +   
Sbjct: 1393 VT-TDAARYKVKAVNIHGSVEDDIRV--DVKKAPKITKGLQDMTVNEHDKQVTLDVKVEA 1449

Query: 954  -HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQETSTMLV 1011
                S KWY ++ EI+         +              ++ G   C + ++  ST   
Sbjct: 1450 FPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETS 1509

Query: 1012 VKETI---PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNKYDFE 1066
             K T+   P  I++L+D  V+E     LEVE+    T  V W R+G E+    + K   +
Sbjct: 1510 AKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRD 1569

Query: 1067 KRGH-IRKLYIRNTSVHDEGEYSCILRDESCT 1097
             + H    L +      +EGEY  ++ +   T
Sbjct: 1570 TQRHETFNLAVNLIKYEEEGEYEVVVTNSMGT 1601



 Score =  128 bits (309), Expect = 2e-27
 Identities = 151/614 (24%), Positives = 252/614 (41%), Gaps = 67/614 (10%)

Query: 510  PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P F +KL R +   +G  ++ + ++ G P+P + W++    I          DD+ V T 
Sbjct: 2248 PTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPI----------DDERVKTS 2297

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            V+ +      GT     ++A    S   +L+++ P  +      V               
Sbjct: 2298 VLPD------GTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQR------- 2344

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                 P F K  K   +  G  + LE ++ A P P++ W+  G  +    NI   +  D 
Sbjct: 2345 -----PKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDG 2399

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIV 746
             +    L +   K    G Y +   N+ G+A     ++I   EK+P  P+ +  L    V
Sbjct: 2400 KV---ALIVDCAKPENAGKYELQVSNKYGDAMGEASVEI---EKKPTKPEFLVRLVPQTV 2453

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802
             +G  V    + VG+P P +TW +N   V    K +      D  S+ +L       +G+
Sbjct: 2454 VEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGL 2513

Query: 803  -YTLKAENSEGIAETSAVITVEEPT--EENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             Y   A N  G AETSA +TV   T  E   E P+F++  +++T  E  ++ L A  T N
Sbjct: 2514 TYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTAN 2573

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            PVP + W ++   +SPS+ I    DG+ + L I N     D+G Y    SN  G+ S  A
Sbjct: 2574 PVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPS-DAGRYSVKISNPLGEESSEA 2632

Query: 920  RVTIDVEKVTFVKHLQKSY---ETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHRE 974
                 V KV    H  +++   +   G+     C+ S     +  W  +   I   D   
Sbjct: 2633 NAA--VHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYH 2690

Query: 975  IIQEGRXXXXXXXXXXXXDVGV--IKCIVKDQE---TSTMLVV-----KETI--PEFIRK 1022
            I ++G             D  V   + I K+ E   T+++ VV     K+ I  P F+++
Sbjct: 2691 IKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKR 2750

Query: 1023 LQDFEV-KEKDVAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
            + D E+ K                +V W   D ++    + K + +  G +R L I +  
Sbjct: 2751 IGDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLR-LIISDLD 2809

Query: 1081 VHDEGEYSCILRDE 1094
              D G+YSC + +E
Sbjct: 2810 EADLGKYSCKITNE 2823



 Score =  127 bits (307), Expect = 3e-27
 Identities = 221/1082 (20%), Positives = 399/1082 (36%), Gaps = 103/1082 (9%)

Query: 761  NPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
            NP P  TW  N    KP   +   + G+   + I+K  K+ D G      +N  G A  +
Sbjct: 1878 NPPPKATWTINGQELKPDSRVRMTNKGEEFKLEIVK-LKMDDAGKIECILKNPLGEARQT 1936

Query: 818  AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPS 876
            A++ V  P +E   P L     ++ T+++K T+   A V  +PVP  TW    +E+ S +
Sbjct: 1937 AMLEVT-PEKELRRPKLK-EGLKDQTIQKKNTLTFKAVVIGDPVPDATWSVDGHELTSEA 1994

Query: 877  ----ETITQNFDGE--------NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
                + I +  D E           L I   +   ++G Y   A N  G+ +  A++T+ 
Sbjct: 1995 FEKYKIILETEDHEIQDGLKECTYTLTIPRCE-RCNAGKYTFFAKNKWGECNSSAQLTV- 2052

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE--GRXX 982
            V +         S    E   ++ + Q +      W  + + +   ++ +I+ +      
Sbjct: 2053 VLRPEIEGPQNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETY 2112

Query: 983  XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI--PEFIRKLQDFEVKE-KDVAILE 1037
                      D G  K + K+   E+S+   +K     P  I  L D +V+  K+++++ 
Sbjct: 2113 RLVFKKALLSDEGYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQVEHTKEISVMV 2172

Query: 1038 VEINSETADVVWERDGE-IIKPKKNKYDFEKRGHIRK-LYIRNTSVHDEGEYSCI---LR 1092
                     + W  +G+ I++ +K+K +      +   L + + +  D G Y  I   ++
Sbjct: 2173 RADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGIYKAIAANVQ 2232

Query: 1093 DESCT-AEVTVVELPPEIITRLQ-NQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149
             E+ T A +T+V+ PP    +L+ ++ V +G     + ++       V W+K+G  I   
Sbjct: 2233 GEADTSARITMVQTPPTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPIDDE 2292

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPE 1204
                  +     KL I      D+G Y   +    G S C   + V++ P     L+  +
Sbjct: 2293 RVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFK 2352

Query: 1205 FILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
             + +P      L  ++      +V W K    +  +           +  +I  C + + 
Sbjct: 2353 DVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPEN 2412

Query: 1264 C-EYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
              +Y   +     DA     +++E     P+ +       +  G  V   V     P P 
Sbjct: 2413 AGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPK 2472

Query: 1319 DEWIVN-SKIIKKCKHTKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNV 1375
              W  N +++I   KH K S      S+ +    N   D   Y+    N  G A+    +
Sbjct: 2473 LTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEAETSAPL 2532

Query: 1376 TIL---DKPSPPGKPNILE-----IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
            T++   +  SP  KP  L            ++    P       ++ +  +   +  ++ 
Sbjct: 2533 TVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDR 2592

Query: 1428 ISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
            I V  +  K    I N   + + R+     N +    +      +KV        P   +
Sbjct: 2593 ILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVF-----MPPHFTQ 2647

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXX 1542
               ++   P  D +  C   GVPQP+V W +DG  +K +   +  R              
Sbjct: 2648 TFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSP 2707

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-------VTAV 1595
                 Y+  A N  GE   +  + +  +       E      ++GD  L        TA 
Sbjct: 2708 DDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTAC 2767

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGT 1653
              G P PEV WY N  KL       + T +   ++R  I +L  +   KY+ + +N  G 
Sbjct: 2768 ASGYPEPEVEWYHNDQKLFPSNRIKMET-DPNGLLRLIISDLDEADLGKYSCKITNEYGG 2826

Query: 1654 SSVEVTLKV------------------YDKPSKPEGPV------IMREISRESVTIEWKP 1689
                  L +                  +DK  +   PV      I+ +++    T+ WKP
Sbjct: 2827 DICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCTLSWKP 2886

Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
             +  G      Y +E  E  N  W  V    R   T  ++ L    +Y FRV  +N  G 
Sbjct: 2887 SIPPGPRAPVTYQLEMCELPNGDWFTVRTGIRSC-TCGVRNLEPFRDYKFRVRVENKYGI 2945

Query: 1750 SE 1751
            S+
Sbjct: 2946 SD 2947



 Score =  123 bits (297), Expect = 5e-26
 Identities = 141/668 (21%), Positives = 282/668 (42%), Gaps = 48/668 (7%)

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194
            W  +G E++  + +++T  G++ KL+I    +DDAG+  C     +G ++ TA+L V   
Sbjct: 1885 WTINGQELKPDSRVRMTNKGEEFKLEIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPE 1944

Query: 1195 SINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTW-----------YKKKSVIEDT 1239
                  +L E +    +   NT  +  V I D   D TW           ++K  +I +T
Sbjct: 1945 KELRRPKLKEGLKDQTIQKKNTLTFKAVVIGDPVPDATWSVDGHELTSEAFEKYKIILET 2004

Query: 1240 EKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297
            E   +   +K+   TL I +C   +  +YT    +         ++       ++  +  
Sbjct: 2005 EDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNSSAQLTVVLRPEIEGPQNV 2064

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDA 1355
             +  G    L+   QA PQ    W  + +++K+ ++ K    + +++  L  KK   +D 
Sbjct: 2065 SVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETYRLVFKKALLSDE 2124

Query: 1356 GIYKLRLENNCGHADVEMNV-TILDKPS---PPGKPNILEIDSSSINICWDE-PENTGNS 1410
            G YK+  +N+ G +  E  +  + +KP+         +      S+ +  D  P+     
Sbjct: 2125 GYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRW 2184

Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             +    +   E    E  +   +T T T + +   + S  ++A A N   +   ++T+  
Sbjct: 2185 LLNGKPIVEDEKHKIESHADAQVTSTLT-VSDFNDSDSGIYKAIAAN---VQGEADTSAR 2240

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY- 1529
              +++        +E+    I  EP   +EL     G P+P V WY++G+ +   +    
Sbjct: 2241 ITMVQTPPTFGKKLERSEDVIEGEP---LELKAKINGSPKPTVVWYKNGEPIDDERVKTS 2297

Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHK 1585
               +                 YK +  N +GE    C V +QQKP      +  K  K  
Sbjct: 2298 VLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFKDVKLP 2357

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGN--KLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            +G+   + A ++  PPPEV W K+G   ++ ++  + +    K ++I +   K  ++ KY
Sbjct: 2358 IGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALI-VDCAKPENAGKY 2416

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK-PPLDDGGLELTKY 1701
             ++ SN  G +  E ++++  KP+KPE  V ++ +   E   ++++   +     +LT  
Sbjct: 2417 ELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWS 2476

Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM-FRVIAQNPVGFSEALESEPIVI 1760
                    +N+ +K++++        +   N+  + + +R IA N  G  EA  S P+ +
Sbjct: 2477 RNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAG--EAETSAPLTV 2534

Query: 1761 KTALDVPS 1768
              A +  S
Sbjct: 2535 IPATNSES 2542



 Score =  121 bits (291), Expect = 3e-25
 Identities = 107/429 (24%), Positives = 172/429 (40%), Gaps = 36/429 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDD 562
            E++   P F+ +L P+   +G  V+FE +  G+P P++TW R  A +I  ++  ++    
Sbjct: 2436 EKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELP 2495

Query: 563  DNVATLVIREVFP-EDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
            D  + L++       D  T+  +A N AG A ++  L V    +    E           
Sbjct: 2496 DGTSVLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEK--------- 2546

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                        P F    K    DEG  ++L     A P P + W   G  + P + I 
Sbjct: 2547 ------------PMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDRIL 2594

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            V  +         L+I N      G Y+V   N  GE S      +      PP   +  
Sbjct: 2595 VTCDGKK----VGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFM-PPHFTQTF 2649

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVK 798
              +    G       +V G P+P + W K+  P+K       K DGD   + +L      
Sbjct: 2650 TDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSP-D 2708

Query: 799  DEGVYTLKAENSEG--IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
            D  VY  +A N EG  +   S  +  +   ++  EPP F+ R  +  + +  T K  A  
Sbjct: 2709 DAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTACA 2768

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKS 915
            +  P P + WY N++ + PS  I    D    + L+I+++D E D G Y C  +N  G  
Sbjct: 2769 SGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLD-EADLGKYSCKITNEYGGD 2827

Query: 916  SHGARVTID 924
               A + +D
Sbjct: 2828 ICHANLNMD 2836



 Score =  113 bits (273), Expect = 4e-23
 Identities = 153/689 (22%), Positives = 282/689 (40%), Gaps = 72/689 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            PEF+ KL+D E+ E       V++  +   DV++ +DG I++ K ++Y+  +    R  Y
Sbjct: 953  PEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVE-KSDRYEVIREHSDRGFY 1011

Query: 1076 ---IRNTSVHDEGEYSCILR----DESC--TAEVTVVELPPEIITRLQNQKVNKGNKATF 1126
               I    + D GEY C+      ++SC  T +VT  +L  ++    + + +  G    F
Sbjct: 1012 ELLIPEVQMSDAGEYKCVASNKWGEDSCEATLKVTTEDLHKDMP---EGEILPPGETPEF 1068

Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY--DCDLDDAGEYSCEV---- 1180
            +           W KDG+  +     ++ +   +  L +       +D G Y+C      
Sbjct: 1069 Q-----------WKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSR 1117

Query: 1181 GNSKCTAILTVEEPSINFTLRLPE---FIL------VPANTDAYLTVEIPD-ETLDVTWY 1230
            G+  C+A LTV   ++N  +R PE    I+      V A   A + +++       V W 
Sbjct: 1118 GHISCSAELTVHG-TVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWT 1176

Query: 1231 KKKSVIEDTEKFT-LISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP 1288
             +   IE   K+  L  D +  +L+I+   ++D  +Y C    +  S T      V+ PP
Sbjct: 1177 HEGKPIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPP 1236

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
            K+     +        + + V+ +  P+P   +  + K IKK +  K   +++   L I+
Sbjct: 1237 KLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVIE 1296

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEIDSS-SINICWDEP 1404
            K    D+G Y +   N         N+ +  KP      GK  I+  +    + +   + 
Sbjct: 1297 KTMLKDSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRV---KI 1353

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISD 1463
            E+   + + +Y  +  EI +++   +K   +T    I    T  + R++  AVN     +
Sbjct: 1354 ESEPEAEVKWYKDD-AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVE 1412

Query: 1464 ASETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                 +  K  K TK +Q  TV +  K +T     D+++       P+P V WY D  ++
Sbjct: 1413 DDIRVDVKKAPKITKGLQDMTVNEHDKQVTL----DVKVEAF----PKPSVKWYLDEMEI 1464

Query: 1523 KTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
               K  +     ++                Y C   N+ G  ETS  + +   P I    
Sbjct: 1465 TETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQL 1524

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKTSVIRIKE 1634
            +D   +   G    +   +EG P P V W +NG ++  D    I   T + +T  + +  
Sbjct: 1525 KDTTVEE--GATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNL 1582

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            +K     +Y +  +N+ GT S +  + V+
Sbjct: 1583 IKYEEEGEYEVVVTNSMGTVSSKSYVTVH 1611



 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 85/313 (27%), Positives = 136/313 (43%), Gaps = 23/313 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P    K  K + V +     L  ++ + PE ++ W     EI   ++    I+ D   Y 
Sbjct: 1329 PKILEKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDH--YVIKKDGETY- 1385

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GES 751
             +LKIT         Y V AVN  G     +   I+   K+ P++ + L+ M V +  + 
Sbjct: 1386 -ILKITGAVTTDAARYKVKAVNIHGS----VEDDIRVDVKKAPKITKGLQDMTVNEHDKQ 1440

Query: 752  VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            V L  +V   P+P++ W  +   +   K   T+ D D     ++K    +  G YT K  
Sbjct: 1441 VTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLS 1500

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N  G  ETSA +TV      N  P + I + ++ TV+E  T+ L   V   P P++ W R
Sbjct: 1501 NECGSTETSAKLTV------NCAPRI-IKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLR 1553

Query: 869  NNEIISPSETITQNFDGENIEL--VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            N   +S    I  + D +  E   +  N+    + G+Y+ V +NS G  S  + VT  V 
Sbjct: 1554 NGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVT--VH 1611

Query: 927  KVTFVKHLQKSYE 939
            KVT    ++   E
Sbjct: 1612 KVTHTDAIEVEEE 1624



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 131/614 (21%), Positives = 249/614 (40%), Gaps = 82/614 (13%)

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL-------TIDGKKQK 1162
            I  ++   +  G K TFE+ L        W KD   +  SN I L       + D    K
Sbjct: 845  IKTIRGADIEPGEKFTFEVALKSKPDTFTWLKDDKPLD-SNAIMLGRIQMRHSEDSYLYK 903

Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRL-----PEFILVPANTD 1213
            L I     DD+G Y+       G + C+A+L V + +    L       PEF++   +T+
Sbjct: 904  LYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKDTE 963

Query: 1214 ----AYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKR---TLIIRKCTEDDQ 1263
                 YL   +    D   DV ++K   ++E ++++ +I +   R    L+I +    D 
Sbjct: 964  LAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMSDA 1023

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             EY CV     ++ K   +  E   K+   +    +  G    +L   +    P  +W  
Sbjct: 1024 GEYKCV-----ASNKWGEDSCEATLKVTTEDLHKDMPEGE---ILPPGET---PEFQWKK 1072

Query: 1324 NSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGH----ADVEMNVTI 1377
            +    +  +  K  +  D  S +L  + V   D G+Y    + + GH    A++ ++ T+
Sbjct: 1073 DGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVHGTV 1132

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--------- 1428
                  P KP +L ++  +  +      N G S +I   V+       +W          
Sbjct: 1133 NQLVREPEKP-VLIVEKRNPVV------NAGGSAMIELQVKGFPKPQVKWTHEGKPIEAG 1185

Query: 1429 -SVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
               K + + + +    I++++   + ++   A NE+  SD +E T   K         P 
Sbjct: 1186 GKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIG-SDTAEMTLTVKT-------PPK 1237

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYEN-RXXXXXXX 1539
            + K ++++    +  +E+     G P+PKV +Y+DGK++K     K   EN +       
Sbjct: 1238 LRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVIEK 1297

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIE 1597
                    Y  +A N+  ++     + +  KP I    E + +   V  E  + +   IE
Sbjct: 1298 TMLKDSGSYSIVATNELAQISEFFNLHVHTKPKIL---EKLGKDKIVSQEEKFELRVKIE 1354

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
              P  EV WYK+  ++++   Y I    +T +++I     + +++Y ++A N  G+   +
Sbjct: 1355 SEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDD 1414

Query: 1658 VTLKVYDKPSKPEG 1671
            + + V   P   +G
Sbjct: 1415 IRVDVKKAPKITKG 1428



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 55/212 (25%), Positives = 89/212 (41%), Gaps = 18/212 (8%)

Query: 634  PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P  +K  +   V+E    + L+ ++ A P+P + W     EI   +     ++SD  +  
Sbjct: 1423 PKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVK- 1481

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I  V     G YT    N  G       L +       P++I+ LK   V +G ++
Sbjct: 1482 --LVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCA----PRIIKQLKDTTVEEGATL 1535

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK--DEGVYTLKA 807
             L  +V G P PT+ W +N + V A   +    D   H    L    +K  +EG Y +  
Sbjct: 1536 HLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVV 1595

Query: 808  ENSEGIAETSAVITVEEPTEENA-----EPPL 834
             NS G   + + +TV + T  +A     EPP+
Sbjct: 1596 TNSMGTVSSKSYVTVHKVTHTDAIEVEEEPPM 1627



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 2/142 (1%)

Query: 1324 NSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            N  I+ +    K   D    S L      + D G+YK+   N  G       +     P 
Sbjct: 3571 NDSIVAESHRVKIDTDEFGRSHLKFSPALSFDQGMYKVVARNKIGQTVARARIVFGSTPE 3630

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQ 1441
             P  P   +   + I + W +P   GNS ++ Y +EY+  D  EW     NI      ++
Sbjct: 3631 EPDSPESDQSSDTEIFLTWKQPRFDGNSPVLCYSLEYKLADDIEWTKKADNIDHEFYLMR 3690

Query: 1442 NLKTNSSYRFRAYAVNEVDISD 1463
             L  +SSY FR  A N +  SD
Sbjct: 3691 GLTPSSSYMFRLAARNAIGWSD 3712



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 10/167 (5%)

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P+P +++ F  E I       ++   +     + L I  + +   G Y  VA N  GEA 
Sbjct: 3030 PKPKVSFYFNDELIESGGRFDMSYTRNGQ---ATLFINKMLERDVGWYEAVATNEHGEAR 3086

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--- 777
              + L+I     E PQ I   +         V   A++VG P P I W K+ KP+ A   
Sbjct: 3087 QRVRLEIA----EMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTR 3142

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            +   S     ++ ++     KDEG+Y++ A N  G   +SA++ VEE
Sbjct: 3143 IKVSSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHVEE 3189



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 2/109 (1%)

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y + A N  G +     +     P +P+ P   +    E + + WK P  DG   +  Y+
Sbjct: 3606 YKVVARNKIGQTVARARIVFGSTPEEPDSPESDQSSDTE-IFLTWKQPRFDGNSPVLCYS 3664

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            +E    D+  W K AD + D E Y ++ L  +  YMFR+ A+N +G+S+
Sbjct: 3665 LEYKLADDIEWTKKAD-NIDHEFYLMRGLTPSSSYMFRLAARNAIGWSD 3712



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 9/114 (7%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            +++ ARN+IG ++      +I  G T   P  P +    +S+   + L W +P  +G SP
Sbjct: 3606 YKVVARNKIGQTVARA---RIVFGSTPEEPDSPES---DQSSDTEIFLTWKQPRFDGNSP 3659

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVS 1949
            +  Y +E+K      WTK        HE + +  +      +FR++A N +G S
Sbjct: 3660 VLCYSLEYKLADDIEWTK--KADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 1/124 (0%)

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            +L+++   S+   + T             A +     P   K+ K   V+EG+ + LE  
Sbjct: 1481 KLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHLEVE 1540

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            +   P P + WL  G E+  D  I ++ ++  H   + L +  +K  +EG Y VV  N  
Sbjct: 1541 VEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFN-LAVNLIKYEEEGEYEVVVTNSM 1599

Query: 717  GEAS 720
            G  S
Sbjct: 1600 GTVS 1603



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 23/96 (23%), Positives = 46/96 (47%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            L V ++  ++++   P F++++       G T +F     GYP P++ W+     + PS 
Sbjct: 2730 LEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSN 2789

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
              +M  D + +  L+I ++   D G ++C   N  G
Sbjct: 2790 RIKMETDPNGLLRLIISDLDEADLGKYSCKITNEYG 2825



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 25/92 (27%), Positives = 47/92 (51%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+ +   ++      V+F+ ++ G P P+I W++    +  S   ++     + A LV
Sbjct: 3097 PQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTRIKVSSFFPDTAVLV 3156

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            I ++  +D G ++  A+N AG  SS+  L VE
Sbjct: 3157 INDIITKDEGLYSVSARNVAGSISSSAMLHVE 3188



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVAT 567
            P FV KL+     + + ++F  +V G P P + +F+   I++ S  +++   + D     
Sbjct: 953  PEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYE 1012

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            L+I EV   DAG + CVA N  G  S    L V
Sbjct: 1013 LLIPEVQMSDAGEYKCVASNKWGEDSCEATLKV 1045



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 39/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%)

Query: 1507 GVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G P+PKV++Y + + +++        T   +               Y+ +A N+HGE   
Sbjct: 3028 GYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQ 3087

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + I + P   I   +I+     G +    A I G+P PE+ WYK+   L       +
Sbjct: 3088 RVRLEIAEMPQF-IRRPEIQYAMHRG-KVRFDARIVGVPYPEIKWYKDWKPLAASTRIKV 3145

Query: 1622 TT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++    T+V+ I ++       Y++ A N AG+ S    L V
Sbjct: 3146 SSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHV 3187



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 12/171 (7%)

Query: 758  VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814
            V G P+P +++  N++ +++        T +   T+   K + +D G Y   A N  G A
Sbjct: 3026 VYGYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEA 3085

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
                 + +       AE P FI R +      +G ++  AR+   P P I WY++ + ++
Sbjct: 3086 RQRVRLEI-------AEMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLA 3138

Query: 875  PSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             S  I   +F  +   LVI ++ ++ D G Y   A N AG  S  A + ++
Sbjct: 3139 ASTRIKVSSFFPDTAVLVINDIITK-DEGLYSVSARNVAGSISSSAMLHVE 3188



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 4/108 (3%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            E+P  +  + AP F+ +         D +T  F   V GYP+P+++++    +I+    F
Sbjct: 2991 ERPPHDNMAQAPRFLRQEHDTQYGVKDQNTNLFWF-VYGYPKPKVSFYFNDELIESGGRF 3049

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
             M Y  +  ATL I ++   D G +  VA N  G A     L I E P
Sbjct: 3050 DMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQRVRLEIAEMP 3097



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 67/294 (22%), Positives = 122/294 (41%), Gaps = 27/294 (9%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGKKLK-TAKATYENR---XXX 1535
            PT+       ++ P E +++  I  G   P PK TW  +G++LK  ++    N+      
Sbjct: 1851 PTITSSNMKDSSRP-ESLDICYIVKGTSNPPPKATWTINGQELKPDSRVRMTNKGEEFKL 1909

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDIK-QKHKVGDEWLV 1592
                         +CI  N  GE   + ++ +  +  +      E +K Q  +  +    
Sbjct: 1910 EIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPEKELRRPKLKEGLKDQTIQKKNTLTF 1969

Query: 1593 TAVIEGIPPPEVIWYKNGNKLEND--KEYNIT-----------TKEKTSVIRIKELKRSH 1639
             AV+ G P P+  W  +G++L ++  ++Y I             KE T  + I   +R +
Sbjct: 1970 KAVVIGDPVPDATWSVDGHELTSEAFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCN 2029

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD-DGGLEL 1698
            + KYT  A N  G  +    L V  +P + EGP  +  I  E+  +  K   +    +  
Sbjct: 2030 AGKYTFFAKNKWGECNSSAQLTVVLRP-EIEGPQNVSVIPGEATELVCKIQANPQAEVHW 2088

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
            TK      E +N +   V+DV  +      +K   + E  ++V+A+N +G S +
Sbjct: 2089 TKDDQVVKETENLK--IVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSS 2140



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 7/118 (5%)

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
            D+ ++++ A N +G ++       R+   +T P  P +P   +   + I +T W  P +D
Sbjct: 3602 DQGMYKVVARNKIGQTVAR----ARIVFGST-PEEPDSPESDQSSDTEIFLT-WKQPRFD 3655

Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            G +P+L Y++  +      W +    +++   + +R L+ + +YM R+ ARN IG S+
Sbjct: 3656 GNSPVLCYSLEYKLADDIEWTKKAD-NIDHEFYLMRGLTPSSSYMFRLAARNAIGWSD 3712



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 3/95 (3%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F ++P+ QY      +  + R+V +P P+I W    + +     I V   S      +
Sbjct: 3097 PQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTRIKV---SSFFPDTA 3153

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
            VL I ++    EG Y+V A N  G  S   +L ++
Sbjct: 3154 VLVINDIITKDEGLYSVSARNVAGSISSSAMLHVE 3188



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT- 567
            AP  +++L+     +G+T+  E +VEG P P + W R    +      ++  D     T 
Sbjct: 1517 APRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETF 1576

Query: 568  -LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             L +  +  E+ G +  V  N+ G  SS + + V
Sbjct: 1577 NLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTV 1610



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 13/181 (7%)

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGI--PPPEVIWYKNGNKLENDKEYNITTKE 1625
            + KP IT SN     + +  D   +  +++G   PPP+  W  NG +L+ D    +T K 
Sbjct: 1848 EAKPTITSSNMKDSSRPESLD---ICYIVKGTSNPPPKATWTINGQELKPDSRVRMTNKG 1904

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVT-LKVYDKPSKPEGPVIMREISR 1680
            +   + I +LK   + K      N  G    T+ +EVT  K   +P   EG  +  +  +
Sbjct: 1905 EEFKLEIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPEKELRRPKLKEG--LKDQTIQ 1962

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
            +  T+ +K  +    +    ++++ HE  +  + K   +  + E + IQ   + C Y   
Sbjct: 1963 KKNTLTFKAVVIGDPVPDATWSVDGHELTSEAFEKY-KIILETEDHEIQDGLKECTYTLT 2021

Query: 1741 V 1741
            +
Sbjct: 2022 I 2022



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 8/113 (7%)

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
            M++V+A+N +G  + +    IV  +  + P            D E +++TW     +G S
Sbjct: 3605 MYKVVARNKIG--QTVARARIVFGSTPEEPDSPESDQSS---DTE-IFLTWKQPRFDGNS 3658

Query: 1798 PIIDYKVEIK-QEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
            P++ Y +E K  +  +W K           ++ L+ +++Y FR+ ARN IG S
Sbjct: 3659 PVLCYSLEYKLADDIEWTKKADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711


>UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein; n=6;
            Danio rerio|Rep: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein - Danio
            rerio
          Length = 2140

 Score =  172 bits (419), Expect = 8e-41
 Identities = 173/747 (23%), Positives = 298/747 (39%), Gaps = 47/747 (6%)

Query: 639  KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
            KP    V     ++  C  +   + D+ W   G EI+P    S+            L I 
Sbjct: 1434 KPLVDTVAHKDGMITLCCELCKAKADVQWKKDGVEIIPSRRFSIRANETERS----LTIH 1489

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILS 755
             + K   G Y   + +    A L + L         P+V+E    L +  V +GE     
Sbjct: 1490 RITKEDAGEYVCESKDDSTSARLRVEL---------PRVVEFLTELHNTTVMEGEDATFK 1540

Query: 756  AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              VV      + W  + +P+K       + +   H++ I K + + D    T +AE   G
Sbjct: 1541 C-VVSPDDVQLVWLMDGEPIKPSDRFQIEQNSLCHTLIIHKVQLL-DSSRITAEAE---G 1595

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            +  + A + V+E         LF  R + +  +E G   L   V+      + W R   +
Sbjct: 1596 LI-SKASLKVQEAQV------LFTKRMEAVMAEEFGEATLETEVSLES-GEVQWMRQGVV 1647

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            I P      + +G    L ITN+ S  D G Y+C   +   +     ++ ++  K+   K
Sbjct: 1648 IQPGPKHKLSQNGCKRILTITNL-SLSDRGTYRCETLHDRTQ----VKLNVEPRKIAIRK 1702

Query: 933  HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
             +    ET E +T   E + SHT V   W  +   I   ++  +   GR           
Sbjct: 1703 GMM-DVETFERETASFEVELSHTDVEGVWQKDGLRIKPNNNWRVSSNGRVHGLTLSNLTM 1761

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D G I    +    +  LVVKET     +KL D  ++E+   +LE E++    DV W++
Sbjct: 1762 EDTGSIVFSAEGLRNTARLVVKETPVAIFKKLSDVRIEEESSVVLECELSRPNVDVRWQK 1821

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
            +G  +K  K    +   G  R L I   S+ D G Y+C + D S + ++ V E   E+IT
Sbjct: 1822 NGIELKSSKTLRIYSM-GRKRCLQIMECSISDSGLYTCEIGDLSTSCKLEVYEHELELIT 1880

Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             L++  + +   A F  EL+  D    W+K+GS I+ ++ I+   +G K  L I +   +
Sbjct: 1881 GLEDLWIKEDQNAVFMCELSMEDMPGEWYKNGSRIRPTSTIKTRTEGTKHFLLICNVKAE 1940

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            D+GE        +  A L VEE  ++    L +   +  +    L   +     DVTWY+
Sbjct: 1941 DSGEIKFVSKQVESVACLEVEELPVSIVRPLRDRTALEKHR-VILECTVSSPNCDVTWYR 1999

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
            +   +E TE   +I +     L+I++   +D+  Y+  + +  S  KL VE       +V
Sbjct: 2000 ENEELESTEHMEIIQEGCYHKLVIQQVALEDEGTYSIEVGEHTSIAKLMVEAQSI--LVV 2057

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                +  ++       L +          W +N + ++   + +         LT K   
Sbjct: 2058 KNIEDVEVRAPETAFFLCEVSVALIKPPVWTLNGETLQSGPNVRIDNQGTVHKLTFKTTS 2117

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL 1378
            +  +G  K       G A     +T+L
Sbjct: 2118 SDMSGTVKF----TTGKAKTTAKLTVL 2140



 Score =  168 bits (408), Expect = 2e-39
 Identities = 202/888 (22%), Positives = 366/888 (41%), Gaps = 62/888 (6%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            S  P  Q +  G D++L C +     P + WLF  + ++PDE   +  +  +      L 
Sbjct: 1254 SGDPDYQEMVTGDDLILACEVSRANAP-VKWLFNEKVLIPDERTHIESQGTLRK----LT 1308

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGESVI 753
            I+N+     G Y   AV    +  +  V+K+    +EPP      E +  +   + E V 
Sbjct: 1309 ISNILVSDSGKYMCDAV----DDKMLTVVKV----QEPPVEFLNKEEVNLVTGYEAEPVT 1360

Query: 754  LSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            L+A +V  P   + W K+   +  +   T S G T + TI  P K  D G YT  A NS+
Sbjct: 1361 LTA-MVSRPNAQVRWLKDWTQISGERFHTASLGLTRTFTI-DPLKKLDSGEYTCDA-NSD 1417

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
               E    + V++   +      F+    +    + G I L   + +     + W ++  
Sbjct: 1418 ---EMHFSLLVKDMRIK------FVKPLVDTVAHKDGMITLCCELCKAKA-DVQWKKDGV 1467

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-F 930
             I PS   +   +     L I  +  E D+G+Y C + +     S  AR+ +++ +V  F
Sbjct: 1468 EIIPSRRFSIRANETERSLTIHRITKE-DAGEYVCESKD----DSTSARLRVELPRVVEF 1522

Query: 931  VKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            +  L  +    EG+    +C  S   V   W  + + I   D  +I Q            
Sbjct: 1523 LTELHNT-TVMEGEDATFKCVVSPDDVQLVWLMDGEPIKPSDRFQIEQNSLCHTLIIHKV 1581

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
               D   I    +   +   L V+E    F ++++    +E   A LE E++ E+ +V W
Sbjct: 1582 QLLDSSRITAEAEGLISKASLKVQEAQVLFTKRMEAVMAEEFGEATLETEVSLESGEVQW 1641

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             R G +I+P   K+   + G  R L I N S+ D G Y C    +    ++ V      I
Sbjct: 1642 MRQGVVIQPGP-KHKLSQNGCKRILTITNLSLSDRGTYRCETLHDRTQVKLNVEPRKIAI 1700

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
               + + +  +   A+FE+EL+  D    W KDG  I+ +N+ +++ +G+   L + +  
Sbjct: 1701 RKGMMDVETFERETASFEVELSHTDVEGVWQKDGLRIKPNNNWRVSSNGRVHGLTLSNLT 1760

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            ++D G         + TA L V+E  +    +L + + +   +   L  E+    +DV W
Sbjct: 1761 MEDTGSIVFSAEGLRNTARLVVKETPVAIFKKLSD-VRIEEESSVVLECELSRPNVDVRW 1819

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
             K    ++ ++   + S  +KR L I +C+  D   YTC + D   +T  K+EV E   +
Sbjct: 1820 QKNGIELKSSKTLRIYSMGRKRCLQIMECSISDSGLYTCEIGDL--STSCKLEVYEHELE 1877

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349
            ++    +  IK   +   + +      P  EW  N   I+     K   +     L I  
Sbjct: 1878 LITGLEDLWIKEDQNAVFMCELSMEDMPG-EWYKNGSRIRPTSTIKTRTEGTKHFLLICN 1936

Query: 1350 VENTDAGIYKL---RLENNCGHADVEMNVTIL----DKPSPPGKPNILE--IDSSSINIC 1400
            V+  D+G  K    ++E+       E+ V+I+    D+ +      ILE  + S + ++ 
Sbjct: 1937 VKAEDSGEIKFVSKQVESVACLEVEELPVSIVRPLRDRTALEKHRVILECTVSSPNCDVT 1996

Query: 1401 W----DEPENTGNSTII----YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
            W    +E E+T +  II    Y+ +  Q++   +  +        TSI  L   +     
Sbjct: 1997 WYRENEELESTEHMEIIQEGCYHKLVIQQVALEDEGTYSIEVGEHTSIAKLMVEAQSILV 2056

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
               + +V++  A ET  +   +    I+ P      + + + PN  I+
Sbjct: 2057 VKNIEDVEVR-APETAFFLCEVSVALIKPPVWTLNGETLQSGPNVRID 2103



 Score =  145 bits (352), Expect = 1e-32
 Identities = 225/1036 (21%), Positives = 402/1036 (38%), Gaps = 95/1036 (9%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C  ++  + ++ W   G E+  DEN ++ +E D      V+  T +    E     
Sbjct: 992  LVLNCE-ISKADAEVCWFCDGMEV--DENDNLKLEDDGIYRRLVIPCTTIDDSAE----- 1043

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GESVILSAQVVGNPRPTIT 767
              V    + ++   +KI   E+ P ++    +S  + +   G+ VIL  +V       + 
Sbjct: 1044 -YVCETADDAVTFWVKI---EEPPVKLSSSKQSGSITESFAGDPVILELEV-SRENAEVC 1098

Query: 768  WCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE---GIAETSAVIT 821
            W K+   V+    +    +G T  ITI  P  +KD G+YT  A +      +  T A +T
Sbjct: 1099 WMKDGMKVEESSNITITENGLTRKITIHCPT-LKDSGIYTCNAIDDTMDFKVKITEAPVT 1157

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            +    +   E  + +  + ++ ++ + +       + N V  +TWY+N   I  +E    
Sbjct: 1158 ILNKDQIKNEHKVML--YDDVVMECELS-------SANGV--VTWYKNGSPIEENERFCL 1206

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSY-E 939
              +G    LVI   + + DSG+Y   A N    S H   VT+    V  + +     Y E
Sbjct: 1207 EEEGTFRSLVILCAELQ-DSGEYTLDAKNDTF-SFH---VTVQEPSVKIIGNSGDPDYQE 1261

Query: 940  TEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
               G  +IL C+ S      KW  N+K +   +   I  +G             D G   
Sbjct: 1262 MVTGDDLILACEVSRANAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVSDSGKYM 1321

Query: 999  CIVKDQETSTMLVVKETIPEFIRKLQDFEVK--EKDVAILEVEINSETADVVWERDGEII 1056
            C   D +  T++ V+E   EF+ K +   V   E +   L   ++   A V W +D   I
Sbjct: 1322 CDAVDDKMLTVVKVQEPPVEFLNKEEVNLVTGYEAEPVTLTAMVSRPNAQVRWLKDWTQI 1381

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
              ++  +     G  R   I      D GEY+C    +     + V ++  + +  L + 
Sbjct: 1382 SGER--FHTASLGLTRTFTIDPLKKLDSGEYTCDANSDEMHFSLLVKDMRIKFVKPLVDT 1439

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
              +K    T   EL K  A V+W KDG EI  S    +  +  ++ L I+    +DAGEY
Sbjct: 1440 VAHKDGMITLCCELCKAKADVQWKKDGVEIIPSRRFSIRANETERSLTIHRITKEDAGEY 1499

Query: 1177 SCEVGNSKCTAILTVEEPSI-NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235
             CE  +   +A L VE P +  F   L    ++      +  V  PD+ + + W      
Sbjct: 1500 VCESKDDSTSARLRVELPRVVEFLTELHNTTVMEGEDATFKCVVSPDD-VQLVWLMDGEP 1558

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295
            I+ +++F +  +    TLII K    D    T       S   LKV+  E          
Sbjct: 1559 IKPSDRFQIEQNSLCHTLIIHKVQLLDSSRITAEAEGLISKASLKVQ--EAQVLFTKRME 1616

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
                +   + TL  +  +      +W+    +I+     K S +     LTI  +  +D 
Sbjct: 1617 AVMAEEFGEATLETEV-SLESGEVQWMRQGVVIQPGPKHKLSQNGCKRILTITNLSLSDR 1675

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
            G Y  R E       V++NV          +P  + I    +++   E E         +
Sbjct: 1676 GTY--RCETLHDRTQVKLNV----------EPRKIAIRKGMMDVETFERETAS------F 1717

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE---TTEYYK 1472
             VE    D  E +  K+  + + +  N + +S+ R     ++ + + D      + E  +
Sbjct: 1718 EVELSHTDV-EGVWQKDGLRIKPN-NNWRVSSNGRVHGLTLSNLTMEDTGSIVFSAEGLR 1775

Query: 1473 -----VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA 1527
                 V+KET +    + K L ++  E    + L C     P   V W ++G +LK++K 
Sbjct: 1776 NTARLVVKETPV---AIFKKLSDVRIEEESSVVLECELSR-PNVDVRWQKNGIELKSSKT 1831

Query: 1528 ----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN-EDIKQ 1582
                +   +               Y C    + G++ TSC + + +  +  I+  ED+  
Sbjct: 1832 LRIYSMGRKRCLQIMECSISDSGLYTC----EIGDLSTSCKLEVYEHELELITGLEDLWI 1887

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K      ++    +E +P     WYKNG+++         T+     + I  +K   S +
Sbjct: 1888 KEDQNAVFMCELSMEDMPGE---WYKNGSRIRPTSTIKTRTEGTKHFLLICNVKAEDSGE 1944

Query: 1643 YTIEASNTAGTSSVEV 1658
                +      + +EV
Sbjct: 1945 IKFVSKQVESVACLEV 1960



 Score =  134 bits (325), Expect = 2e-29
 Identities = 127/557 (22%), Positives = 243/557 (43%), Gaps = 27/557 (4%)

Query: 818  AVITVEEPTEENAEPPL-FINRFQEITVKEKGTIKLV--ARVTRNPVPSITWYRNNEIIS 874
            AV   +  T ++ EPP+  ++   +I ++   + ++V    ++R+    + W+++   + 
Sbjct: 865  AVFQSDNITIQSEEPPITIVDPKDDIHMERYVSEEIVLNCELSRSN-GEVQWFKDGLKLQ 923

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             ++ I  + +G    ++I    S+ DSG+Y C     AG  S   ++ I    V FV   
Sbjct: 924  ETDNIRLSAEGPYRRVIIFCA-SKRDSGEYVC----DAGGDSVFFQLLITEAPVRFVSPS 978

Query: 935  QKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            +   E      + ++L C+ S       W+ +  E+   D+ ++  +G            
Sbjct: 979  ESEVEVCIMSSEKLVLNCEISKADAEVCWFCDGMEVDENDNLKLEDDGIYRRLVIPCTTI 1038

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---DVAILEVEINSETADVV 1048
             D     C   D   +  + ++E   +     Q   + E    D  ILE+E++ E A+V 
Sbjct: 1039 DDSAEYVCETADDAVTFWVKIEEPPVKLSSSKQSGSITESFAGDPVILELEVSRENAEVC 1098

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W +DG  ++   N     + G  RK+ I   ++ D G Y+C   D++   +V + E P  
Sbjct: 1099 WMKDGMKVEESSN-ITITENGLTRKITIHCPTLKDSGIYTCNAIDDTMDFKVKITEAPVT 1157

Query: 1109 IITR--LQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            I+ +  ++N+ KV   +    E EL+  + +V W+K+GS I+ +    L  +G  + L I
Sbjct: 1158 ILNKDQIKNEHKVMLYDDVVMECELSSANGVVTWYKNGSPIEENERFCLEEEGTFRSLVI 1217

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEFILVPANTDAYLTVEIPDE 1223
               +L D+GEY+ +  N   +  +TV+EPS+        P++  +    D  L  E+   
Sbjct: 1218 LCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGDPDYQEMVTGDDLILACEVSRA 1277

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
               V W   + V+   E+  + S    R L I      D  +Y C  +D K  T +KV+ 
Sbjct: 1278 NAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVSDSGKYMCDAVDDKMLTVVKVQ- 1336

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSK 1341
             E P + ++ E E  +  G +   +       +PN +  W+ +   I   +    S+   
Sbjct: 1337 -EPPVEFLNKE-EVNLVTGYEAEPVTLTAMVSRPNAQVRWLKDWTQISGERFHTASL-GL 1393

Query: 1342 SASLTIKKVENTDAGIY 1358
            + + TI  ++  D+G Y
Sbjct: 1394 TRTFTIDPLKKLDSGEY 1410



 Score =  122 bits (293), Expect = 1e-25
 Identities = 111/388 (28%), Positives = 168/388 (43%), Gaps = 40/388 (10%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-------D 783
            + +P  +I+PL S+ V +GE    S ++ G+P P + W K+ K +  +   +       D
Sbjct: 147  DNKPYFLIKPL-SLRVDRGEDAAFSCKITGDPLPQVVWEKDGKQLNEIYESAHYHVGQQD 205

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------------------E 824
            G    + I K +   D GVY  KA N  G A T AV+ VE                    
Sbjct: 206  GGWFQLKIFKTR-TPDGGVYMCKAVNKHGEAITGAVLLVEPIPEHREGSMTNGYTNGHYS 264

Query: 825  PTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            P    A    EP L +++ ++ TV E    K    VT  P P I W RN EII PS    
Sbjct: 265  PQHSRAKHSKEPHLNVSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNGEIIMPSRRHL 324

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
               D E    +      + D+G Y C ASN+ G +    ++++    V F + LQ S E 
Sbjct: 325  IFEDREGYYTLKVLYCKQQDTGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDS-EF 383

Query: 941  EEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
             E    +LEC+    ++ST WY   + +   +   + Q+G             D GV  C
Sbjct: 384  RERDVAVLECEVPEESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTIQNVGADDDGVYLC 443

Query: 1000 IVKD-QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
             + D  +T   L VK TI   ++KL +  EV E + A   VE+  +  D+ W +DG  ++
Sbjct: 444  EMPDGGKTIAELAVKGTI---VKKLPRRLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQ 500

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
             + ++   +  G    L   NTS  D G
Sbjct: 501  -ETHQTIIKSFGKTHILVFVNTSYQDSG 527



 Score =  120 bits (288), Expect = 6e-25
 Identities = 135/641 (21%), Positives = 259/641 (40%), Gaps = 40/641 (6%)

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            +L  E++    +V W +DG  ++   N       G  R++ I   S  D GEY C    +
Sbjct: 901  VLNCELSRSNGEVQWFKDGLKLQETDN-IRLSAEGPYRRVIIFCASKRDSGEYVCDAGGD 959

Query: 1095 SCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151
            S   ++ + E P   ++  +++    +    K     E++K DA V WF DG E+  +++
Sbjct: 960  SVFFQLLITEAPVRFVSPSESEVEVCIMSSEKLVLNCEISKADAEVCWFCDGMEVDENDN 1019

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP-- 1209
            ++L  DG  ++L I    +DD+ EY CE  +   T  + +EEP +  +       +    
Sbjct: 1020 LKLEDDGIYRRLVIPCTTIDDSAEYVCETADDAVTFWVKIEEPPVKLSSSKQSGSITESF 1079

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
            A     L +E+  E  +V W K    +E++   T+  +   R + I   T  D   YTC 
Sbjct: 1080 AGDPVILELEVSRENAEVCWMKDGMKVEESSNITITENGLTRKITIHCPTLKDSGIYTCN 1139

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
             +D   T   KV++ E P  I++ ++   E+++    DV +  +  +       W  N  
Sbjct: 1140 AID--DTMDFKVKITEAPVTILNKDQIKNEHKVMLYDDVVMECELSS-ANGVVTWYKNGS 1196

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
             I++ +      +    SL I   E  D+G Y L  +N+     V +    +      G 
Sbjct: 1197 PIEENERFCLEEEGTFRSLVILCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGD 1256

Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446
            P+  E+ +    I   E  +  N+ + +   E   I           T  + +I N+  +
Sbjct: 1257 PDYQEMVTGDDLILACE-VSRANAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVS 1315

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE----KPLKNITTEPNEDIELT 1502
             S ++   AV++             K++   K+Q P VE    + +  +T    E + LT
Sbjct: 1316 DSGKYMCDAVDD-------------KMLTVVKVQEPPVEFLNKEEVNLVTGYEAEPVTLT 1362

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             +    P  +V W +D  ++   +   A+                   Y C A +D  E+
Sbjct: 1363 AMVSR-PNAQVRWLKDWTQISGERFHTASLGLTRTFTIDPLKKLDSGEYTCDANSD--EM 1419

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
              S +V   +   +    + +   HK G   L   + +     +V W K+G ++   + +
Sbjct: 1420 HFSLLVKDMRIKFVKPLVDTV--AHKDGMITLCCELCKA--KADVQWKKDGVEIIPSRRF 1475

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            +I   E    + I  + +  + +Y  E+ + + ++ + V L
Sbjct: 1476 SIRANETERSLTIHRITKEDAGEYVCESKDDSTSARLRVEL 1516



 Score =  115 bits (276), Expect = 2e-23
 Identities = 172/818 (21%), Positives = 304/818 (37%), Gaps = 60/818 (7%)

Query: 463  TEEKGWVPAQYLMDENNYTQYL--QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKH 520
            T+E+   PAQ    + N  Q +  ++ +  KI +    EK     Q   P F+ K     
Sbjct: 101  TQEQQTQPAQAPPPQQNDVQVIPPEQDIKMKIQQQVGVEKKKDPFQDNKPYFLIKPLSLR 160

Query: 521  TPDGSTVQFECQVEGYPRPQITW---FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
               G    F C++ G P PQ+ W    +Q   I  S  + +   D     L I +    D
Sbjct: 161  VDRGEDAAFSCKITGDPLPQVVWEKDGKQLNEIYESAHYHVGQQDGGWFQLKIFKTRTPD 220

Query: 578  AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
             G + C A N  G A +   L+VE P+ +H                  +       P  +
Sbjct: 221  GGVYMCKAVNKHGEAITGAVLLVE-PIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLN 279

Query: 638  -KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
              K K   V EG      C +   P+P+I W   GE I+P       I  D   Y + LK
Sbjct: 280  VSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNGEIIMPSRR--HLIFEDREGYYT-LK 336

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            +   K+   G Y   A N  G     + L +K     P +    L+    R+ +  +L  
Sbjct: 337  VLYCKQQDTGLYICAASNALGNTLSAVQLSVK---GPPVRFKRALQDSEFRERDVAVLEC 393

Query: 757  QVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGI 813
            +V      T  + ++ +         +  G    +TI +     D+GVY  +  +  + I
Sbjct: 394  EVPEESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTI-QNVGADDDGVYLCEMPDGGKTI 452

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EI 872
            AE +   T+ +      E            V E         V ++ +  I W+++  ++
Sbjct: 453  AELAVKGTIVKKLPRRLE------------VMEGENAAFFVEVEQDDM-DICWFKDGLQL 499

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
                +TI ++F G+   LV  N   + DSG    +A  S   S    +       +  V 
Sbjct: 500  QETHQTIIKSF-GKTHILVFVNTSYQ-DSGTITFMAGRSTTSSKLRVKTARHCPPICPVG 557

Query: 933  HLQKSYETEEGKTVILECQTS-----HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
                +   + G  V+L    S      T  + +   ++E+   + +  +           
Sbjct: 558  VQMNTDCCQNG--VVLSWSPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTETGTSAEVL 615

Query: 988  XXXXXDVGVIK---CIVKDQETSTMLVVKETI-----PEFIRKLQDFEVKEKDVAILEVE 1039
                   G  +   C V     S  +   + +     P+    L++  V E + A+  +E
Sbjct: 616  GDSVPCEGDFRFRICCVNKYGRSGHVEFPKVVHLAPGPKIKSPLKNAVVTEGEDAVFSIE 675

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT-SVHDEGEYSCILRDESCTA 1098
            ++SE     +    ++ + +       K  HI  L IR   +V+D  E + I      +A
Sbjct: 676  LSSELIGTWFLNSQQLQQSEHFSMTQSKNQHI--LRIRQVPNVYDGAEITFIATGVRDSA 733

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158
             + + E+  +  T L       GN      E+++  A V+WFKDG E+   + + +  DG
Sbjct: 734  SLQIKEMDTKKSTEL-------GNPIVLYCEVSQPTATVQWFKDGKELHAEDGLNIQSDG 786

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF-TLRLPEFILVPANTD-AYL 1216
              +++ I+  +   +G Y+C+  N   T  + VE P + F  ++  E        D   L
Sbjct: 787  NMRRIIIHSAEYSHSGVYTCQSNNDILTFNVNVEAPPVLFKEIKAEERQKSAMELDPVVL 846

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
            T EI        W+K    +  ++  T+ S+    T++
Sbjct: 847  TCEISQPEAPSCWFKDGVAVFQSDNITIQSEEPPITIV 884



 Score =  110 bits (264), Expect = 5e-22
 Identities = 130/564 (23%), Positives = 234/564 (41%), Gaps = 43/564 (7%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+   V  G+D +L+C++   P+PD+ W  K E I P+    +  +  ++     L I+ 
Sbjct: 14   PRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVY----TLYISG 69

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            V     G Y   A N  GE      LK++  E+   Q  +P ++   +Q +      QV+
Sbjct: 70   VTMEDAGQYICRAKNNIGETYAAATLKVQ--EETQEQQTQPAQAPPPQQND-----VQVI 122

Query: 760  GNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVK-DEGVYTLKAENSEGIAETS 817
              P   I   K  + V     K    D     ++KP  ++ D G     A + +   +  
Sbjct: 123  P-PEQDIKM-KIQQQVGVEKKKDPFQDNKPYFLIKPLSLRVDRGEDA--AFSCKITGDPL 178

Query: 818  AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
              +  E+  ++  E  ++ +    +  ++ G  +L    TR P   +  Y    +    E
Sbjct: 179  PQVVWEKDGKQLNE--IYESAHYHVGQQDGGWFQLKIFKTRTPDGGV--YMCKAVNKHGE 234

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
             IT       +E +  + +  + +G      S    ++ H     ++V K        K 
Sbjct: 235  AITGAV--LLVEPIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLNVSKA-------KK 285

Query: 938  YETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX--XXD 993
            +   EGK     C  +     +  W  N  EI     R +I E R              D
Sbjct: 286  FTVTEGKHAKFRCYVTGKPKPEIVWKRNG-EIIMPSRRHLIFEDREGYYTLKVLYCKQQD 344

Query: 994  VGVIKCIVKDQETSTMLVVKETIP----EFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
             G+  C   +   +T+  V+ ++      F R LQD E +E+DVA+LE E+  E+    W
Sbjct: 345  TGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDSEFRERDVAVLECEVPEESISTAW 404

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
              + + ++   NKY+ E++G  R+L I+N    D+G Y C + D   T  +  + +   I
Sbjct: 405  YLEDQRLQ-HGNKYNMEQKGTWRRLTIQNVGADDDGVYLCEMPDGGKT--IAELAVKGTI 461

Query: 1110 ITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            + +L  + +V +G  A F +E+ + D  + WFKDG ++Q ++   +   GK   L   + 
Sbjct: 462  VKKLPRRLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQETHQTIIKSFGKTHILVFVNT 521

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVE 1192
               D+G  +   G S  ++ L V+
Sbjct: 522  SYQDSGTITFMAGRSTTSSKLRVK 545



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 115/561 (20%), Positives = 214/561 (38%), Gaps = 33/561 (5%)

Query: 1110 ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIY 1166
            +++ +   V +G  A F   +T K    + W ++G EI   +   L  + ++    LK+ 
Sbjct: 280  VSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNG-EIIMPSRRHLIFEDREGYYTLKVL 338

Query: 1167 DCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
             C   D G Y C     +GN+     L+V+ P + F   L +      +  A L  E+P+
Sbjct: 339  YCKQQDTGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDSEFRERDV-AVLECEVPE 397

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            E++   WY +   ++   K+ +      R L I+    DD   Y C + D   T     E
Sbjct: 398  ESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTIQNVGADDDGVYLCEMPDGGKTI---AE 454

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            +      +    R   +  G +    V+ +     +  W  +   +++   T      K+
Sbjct: 455  LAVKGTIVKKLPRRLEVMEGENAAFFVEVEQ-DDMDICWFKDGLQLQETHQTIIKSFGKT 513

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICW 1401
              L        D+G        +   + + +       P  P G     +   + + + W
Sbjct: 514  HILVFVNTSYQDSGTITFMAGRSTTSSKLRVKTARHCPPICPVGVQMNTDCCQNGVVLSW 573

Query: 1402 DEPENTGNSTI-IYYVVEYQEIDTTEW---ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
                N  NST    YV+E QE+ + EW   ++ +  T  +    ++     +RFR   VN
Sbjct: 574  SPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTETGTSAEVLGDSVPCEGDFRFRICCVN 633

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
            +      S   E+ KV+       P ++ PLKN      ED   +       +   TW+ 
Sbjct: 634  KY---GRSGHVEFPKVVH--LAPGPKIKSPLKNAVVTEGEDAVFSIELSS--ELIGTWFL 686

Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
            + ++L+ ++     +               Y      D  E+ T    G++    + I  
Sbjct: 687  NSQQLQQSEHFSMTQSKNQHILRIRQVPNVY------DGAEI-TFIATGVRDSASLQIKE 739

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
             D K+  ++G+  ++   +   P   V W+K+G +L  +   NI +      I I   + 
Sbjct: 740  MDTKKSTELGNPIVLYCEVSQ-PTATVQWFKDGKELHAEDGLNIQSDGNMRRIIIHSAEY 798

Query: 1638 SHSSKYTIEASNTAGTSSVEV 1658
            SHS  YT +++N   T +V V
Sbjct: 799  SHSGVYTCQSNNDILTFNVNV 819



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 131/559 (23%), Positives = 210/559 (37%), Gaps = 74/559 (13%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP  +   RP     G+    +CQ+ G P+P + W R+   I P   +++   D  V TL
Sbjct: 7    APRVLGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRI-TQDGKVYTL 65

Query: 569  VIREVFPEDAGTFTCVAKNAAG--FASSTTELIVE----------APLSDHGSEMTV--- 613
             I  V  EDAG + C AKN  G  +A++T ++  E          AP         +   
Sbjct: 66   YISGVTMEDAGQYICRAKNNIGETYAAATLKVQEETQEQQTQPAQAPPPQQNDVQVIPPE 125

Query: 614  ----XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
                             D  +   P F  KP +  VD G D    C++   P P + W  
Sbjct: 126  QDIKMKIQQQVGVEKKKDPFQDNKPYFLIKPLSLRVDRGEDAAFSCKITGDPLPQVVWEK 185

Query: 670  KGE---EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
             G+   EI    +  V  + D   +   LKI   +    G Y   AVN+ GEA    VL 
Sbjct: 186  DGKQLNEIYESAHYHVG-QQDGGWF--QLKIFKTRTPDGGVYMCKAVNKHGEAITGAVLL 242

Query: 727  IK---------------TGEKEP----------PQV-IEPLKSMIVRQGESVILSAQVVG 760
            ++                G   P          P + +   K   V +G+       V G
Sbjct: 243  VEPIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLNVSKAKKFTVTEGKHAKFRCYVTG 302

Query: 761  NPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
             P+P I W +N + +    + L  +     +++ +L  K+ +D G+Y   A N+ G   +
Sbjct: 303  KPKPEIVWKRNGEIIMPSRRHLIFEDREGYYTLKVLYCKQ-QDTGLYICAASNALGNTLS 361

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            +  ++V+ P      P  F    Q+   +E+    L   V    + S  WY  ++ +   
Sbjct: 362  AVQLSVKGP------PVRFKRALQDSEFRERDVAVLECEVPEESI-STAWYLEDQRLQHG 414

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
                    G    L I NV ++ D G Y C   +  GK+   A + +   K T VK L +
Sbjct: 415  NKYNMEQKGTWRRLTIQNVGAD-DDGVYLCEMPD-GGKTI--AELAV---KGTIVKKLPR 467

Query: 937  SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDV 994
              E  EG+      +     +   W+ +  ++    H+ II+  G+            D 
Sbjct: 468  RLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQ-ETHQTIIKSFGKTHILVFVNTSYQDS 526

Query: 995  GVIKCIVKDQETSTMLVVK 1013
            G I  +     TS+ L VK
Sbjct: 527  GTITFMAGRSTTSSKLRVK 545



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 60/289 (20%), Positives = 121/289 (41%), Gaps = 18/289 (6%)

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA-RVTIDVEKVTFVKHLQKSYETEEG 943
            G + E++  +V  E D   ++    N  G+S H      + +     +K   K+    EG
Sbjct: 609  GTSAEVLGDSVPCEGDFR-FRICCVNKYGRSGHVEFPKVVHLAPGPKIKSPLKNAVVTEG 667

Query: 944  KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXXXDVGVIKCIVK 1002
            +  +   + S  +   W+ N +++   +H  + Q + +            D   I  I  
Sbjct: 668  EDAVFSIELSSELIGTWFLNSQQLQQSEHFSMTQSKNQHILRIRQVPNVYDGAEITFIAT 727

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062
                S  L +KE   +   +L        +  +L  E++  TA V W +DG+ +   ++ 
Sbjct: 728  GVRDSASLQIKEMDTKKSTEL-------GNPIVLYCEVSQPTATVQWFKDGKELH-AEDG 779

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG- 1121
             + +  G++R++ I +      G Y+C   ++  T  V  VE PP +   ++ ++  K  
Sbjct: 780  LNIQSDGNMRRIIIHSAEYSHSGVYTCQSNNDILTFNVN-VEAPPVLFKEIKAEERQKSA 838

Query: 1122 ---NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
               +      E+++ +A   WFKDG  +  S++I  TI  ++  + I D
Sbjct: 839  MELDPVVLTCEISQPEAPSCWFKDGVAVFQSDNI--TIQSEEPPITIVD 885



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 12/242 (4%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            P+I + L+N  V +G  A F IEL+  + +  WF +  ++Q S H  +T    +  L+I 
Sbjct: 653  PKIKSPLKNAVVTEGEDAVFSIELSS-ELIGTWFLNSQQLQQSEHFSMTQSKNQHILRIR 711

Query: 1167 DC-DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
               ++ D  E +      + +A L ++E     +  L   I+        L  E+   T 
Sbjct: 712  QVPNVYDGAEITFIATGVRDSASLQIKEMDTKKSTELGNPIV--------LYCEVSQPTA 763

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
             V W+K    +   +   + SD   R +II          YTC   +   T  + VE   
Sbjct: 764  TVQWFKDGKELHAEDGLNIQSDGNMRRIIIHSAEYSHSGVYTCQSNNDILTFNVNVEAPP 823

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
               K +  E   +     D  +L    + P+    W  +   + +  +   +I S+   +
Sbjct: 824  VLFKEIKAEERQKSAMELDPVVLTCEISQPEAPSCWFKDGVAVFQSDNI--TIQSEEPPI 881

Query: 1346 TI 1347
            TI
Sbjct: 882  TI 883



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 22/86 (25%), Positives = 38/86 (44%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G + ++   I G P P+VIW +    +  +  Y IT   K   + I  +    + +Y 
Sbjct: 20   KCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYISGVTMEDAGQYI 79

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPE 1670
              A N  G +    TLKV ++  + +
Sbjct: 80   CRAKNNIGETYAAATLKVQEETQEQQ 105



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 4/160 (2%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++ W+K+G +L+   +  I +  KT ++         S   T  A  +  +S + V    
Sbjct: 489  DICWFKDGLQLQETHQTIIKSFGKTHILVFVNTSYQDSGTITFMAGRSTTSSKLRVKTAR 548

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKP-PLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            +  P  P G  +  +  +  V + W P P        + Y +E+ E  +  W +    + 
Sbjct: 549  HCPPICPVGVQMNTDCCQNGVVLSWSPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTET 608

Query: 1722 DVETYCIQKLNENCE--YMFRVIAQNPVGFSEALESEPIV 1759
                  +   +  CE  + FR+   N  G S  +E   +V
Sbjct: 609  GTSAEVLGD-SVPCEGDFRFRICCVNKYGRSGHVEFPKVV 647



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 22/193 (11%)

Query: 1512 KVTWYRDGKKLKTAK--ATYENRXXXXXXXX--XXXXXXXYKCIAFNDHGEVETSCVVGI 1567
            +V W +DG K++ +      EN                  Y C A +D  + +    V I
Sbjct: 1096 EVCWMKDGMKVEESSNITITENGLTRKITIHCPTLKDSGIYTCNAIDDTMDFK----VKI 1151

Query: 1568 QQKPVITISNEDIKQKHKVG--DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             + PV  ++ + IK +HKV   D+ ++   +       V WYKNG+ +E ++ + +  + 
Sbjct: 1152 TEAPVTILNKDQIKNEHKVMLYDDVVMECELSSANGV-VTWYKNGSPIEENERFCLEEEG 1210

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSKP--------EGPVI 1674
                + I   +   S +YT++A N   +  V   E ++K+      P        +  ++
Sbjct: 1211 TFRSLVILCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGDPDYQEMVTGDDLIL 1270

Query: 1675 MREISRESVTIEW 1687
              E+SR +  ++W
Sbjct: 1271 ACEVSRANAPVKW 1283



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/80 (31%), Positives = 37/80 (46%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P+++ Y R   +K G+D  L       PQP+  W   ++ I      + + D K  +L I
Sbjct: 8    PRVLGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYI 67

Query: 1348 KKVENTDAGIYKLRLENNCG 1367
              V   DAG Y  R +NN G
Sbjct: 68   SGVTMEDAGQYICRAKNNIG 87



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
            L  P  +LV   TDA L  +I  D   DV W +K   I    ++ +  D K  TL I   
Sbjct: 11   LGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYISGV 70

Query: 1259 TEDDQCEYTC 1268
            T +D  +Y C
Sbjct: 71   TMEDAGQYIC 80


>UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA;
            n=1; Apis mellifera|Rep: PREDICTED: similar to CG14964-PA
            - Apis mellifera
          Length = 1434

 Score =  172 bits (419), Expect = 8e-41
 Identities = 108/391 (27%), Positives = 184/391 (47%), Gaps = 15/391 (3%)

Query: 1381 PSPPGKPNIL----EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNI-T 1434
            P+PPGKP ++    E     + I W+   + G S I+ Y+VE++ + +  W+ S   + T
Sbjct: 30   PAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLCT 89

Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITT 1493
              + ++  L+    Y+FR  A N V +S  SE ++   V  +  + S P  +  +K+ T 
Sbjct: 90   FPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTV 149

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549
              NE  E    F G P PK+ W++DG ++    +T   T   +                K
Sbjct: 150  LENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIK 209

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIWYK 1608
            C A N  G   T   + ++  P I +  +         DE +   V + G PPP VIWY 
Sbjct: 210  CTATNRAGHASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYH 269

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            +G  + +D+ +   + +  S+++I + KR    +Y ++A N  G  +    + V D+P+ 
Sbjct: 270  DGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAINKLGEDTSSFLVTVTDRPAA 329

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P    +   + R SV++ W+ P DDGG ++  Y +E +    + W+K A   R  +   +
Sbjct: 330  PGKATVTMTLGR-SVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLK-ATTSRQTKA-TL 386

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
             +L E  EY FRV A+NP G SE  E   ++
Sbjct: 387  SELIEGSEYKFRVKAENPYGVSEPSEESDVI 417



 Score =  109 bits (262), Expect = 8e-22
 Identities = 65/248 (26%), Positives = 112/248 (45%), Gaps = 6/248 (2%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-E 1285
            + W+K    I  + +  +I++  K  L+I +   +D+ E  C   +       K  ++ E
Sbjct: 169  IAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTKARLILE 228

Query: 1286 FPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSK 1341
             PPKI     YE     ++   + L V     P P+  W  + +++    +H   S+D +
Sbjct: 229  APPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGE 288

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            S  L I   +  D G Y ++  N  G       VT+ D+P+ PGK  +      S+++ W
Sbjct: 289  SI-LKIPDAKRVDRGEYVVKAINKLGEDTSSFLVTVTDRPAAPGKATVTMTLGRSVSLTW 347

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
             EPE+ G   I  Y+VEY  I    W+      +T+ ++  L   S Y+FR  A N   +
Sbjct: 348  QEPEDDGGCKIGTYIVEYYRIGWDVWLKATTSRQTKATLSELIEGSEYKFRVKAENPYGV 407

Query: 1462 SDASETTE 1469
            S+ SE ++
Sbjct: 408  SEPSEESD 415



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 58/227 (25%), Positives = 103/227 (45%), Gaps = 13/227 (5%)

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           +F+      V ++R  E S P+ + ++      PQ    +K   V + E      +  G+
Sbjct: 105 QFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTVLENEQAEFVVRFTGS 164

Query: 762 PRPTITWCKNNKPV-KALPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
           P P I W K+   +  +  T+   ++  S+ ++    + DEG     A N  G A T A 
Sbjct: 165 PLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTKAR 224

Query: 820 ITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
           + +E P      P + + R  E  +  ++  TI+L   +   P PS+ WY + E++S  E
Sbjct: 225 LILEAP------PKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSSDE 278

Query: 878 T-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             + ++ DGE+I L I +    +D G+Y   A N  G+ +    VT+
Sbjct: 279 RHVFESMDGESI-LKIPDA-KRVDRGEYVVKAINKLGEDTSSFLVTV 323



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 46/181 (25%), Positives = 87/181 (48%), Gaps = 9/181 (4%)

Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
           + ++A+N+ G++  S +      T +   A  P F    ++ TV E    + V R T +P
Sbjct: 106 FRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTVLENEQAEFVVRFTGSP 165

Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
           +P I W+++  EI S   T      G+++ L+     +  D G+ KC A+N AG +S  A
Sbjct: 166 LPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALN--DEGEIKCTATNRAGHASTKA 223

Query: 920 RVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREII 976
           R+ ++   K+   +  +     E+ +T+ L+   +     S  WYH+ + +S  D R + 
Sbjct: 224 RLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSS-DERHVF 282

Query: 977 Q 977
           +
Sbjct: 283 E 283



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 2/92 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P+ P    V+ +  RSV+L W EPE +GG  I  YI+E+  +    W K  T      + 
Sbjct: 327  PAAPGKATVTMTLGRSVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLKATT--SRQTKA 384

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
             +  + E  E  FR+ AEN  GVS P+E   V
Sbjct: 385  TLSELIEGSEYKFRVKAENPYGVSEPSEESDV 416



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 13/196 (6%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F  + K   V E        R    P P IAW   G EI       +  ES      S
Sbjct: 138 PQFDLEVKDTTVLENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGK----S 193

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGE 750
           VL I       EG     A NR G AS    L ++     PP++  P +    ++  Q E
Sbjct: 194 VLLIHQTALNDEGEIKCTATNRAGHASTKARLILEA----PPKIRLPRQYEDGLLFEQDE 249

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
           ++ L   + G P P++ W  + + V +         D  SI  +   K  D G Y +KA 
Sbjct: 250 TIRLKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAI 309

Query: 809 NSEGIAETSAVITVEE 824
           N  G   +S ++TV +
Sbjct: 310 NKLGEDTSSFLVTVTD 325



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 79/401 (19%), Positives = 144/401 (35%), Gaps = 24/401 (5%)

Query: 1666 PSKPEGPVIMR---EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
            P+ P  P+++    E   + V I W+    +GG  +  Y +E     +  W++       
Sbjct: 30   PAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLCT 89

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXXXXXX 1778
                 +  L     Y FRV AQN VG S   E S+P+ +   ++    P           
Sbjct: 90   FPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTV 149

Query: 1779 IDNESV-YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
            ++NE   ++  F               EI    ++ +           I + ++N   + 
Sbjct: 150  LENEQAEFVVRFTGSPLPKIAWFKDGFEIFSS-RRTRIITESGKSVLLIHQTALNDEGEI 208

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
            +  A N  G    + S     I +       PR +       +  T++     +    P 
Sbjct: 209  KCTATNRAG----HASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPS 264

Query: 1898 TNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
              +  + + V         ++ G S+ +  I + K  D   + + A N +G    T S  
Sbjct: 265  VIWYHDGEVVSSDERHVFESMDGESILK--IPDAKRVDRGEYVVKAINKLGED--TSSFL 320

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
            V +      P   T  + +   G ++ +T W  PE DGG  +  Y +    +   +W++ 
Sbjct: 321  VTVTDRPAAPGKATVTMTL---GRSVSLT-WQEPEDDGGCKIGTYIVEYYRIGWDVWLKA 376

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
                    K  + +L E   Y  R+ A N  G+SEP E  +
Sbjct: 377  --TTSRQTKATLSELIEGSEYKFRVKAENPYGVSEPSEESD 415



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 63/271 (23%), Positives = 111/271 (40%), Gaps = 23/271 (8%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            G P P++ W+K+G ++ + +   I T+   SV+ I +   +   +    A+N AG +S +
Sbjct: 163  GSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTK 222

Query: 1658 VTLKVYDKPSK-------PEGPVIMR-EISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
              L + + P K        +G +  + E  R  V++  +PP       +  +  E    D
Sbjct: 223  ARL-ILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPS----VIWYHDGEVVSSD 277

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
                 +  D +  ++    ++++   EY+ + I  N +G     E     + T  D P+ 
Sbjct: 278  ERHVFESMDGESILKIPDAKRVDRG-EYVVKAI--NKLG-----EDTSSFLVTVTDRPAA 329

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQK 1828
                     +   SV +TW   E +GG  I  Y VE  + G   W          A + +
Sbjct: 330  PGKATVTMTL-GRSVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLKATTSRQTKATLSE 388

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
            L   + Y+FR+ A N  G S P    D I I
Sbjct: 389  LIEGSEYKFRVKAENPYGVSEPSEESDVIFI 419



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 11/191 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            P+    +++  V +  +A F +  T G  L  + WFKDG EI  S   ++  +  K  L 
Sbjct: 138  PQFDLEVKDTTVLENEQAEFVVRFT-GSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLL 196

Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVE 1219
            I+   L+D GE  C      G++   A L +E  P I    +  + +L   +    L V 
Sbjct: 197  IHQTALNDEGEIKCTATNRAGHASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVS 256

Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
            +       V WY    V+   E+    S   +  L I      D+ EY    ++   + T
Sbjct: 257  LAGRPPPSVIWYHDGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAINKLGEDT 316

Query: 1277 TKLKVEVVEFP 1287
            +   V V + P
Sbjct: 317  SSFLVTVTDRP 327



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP F  +++     +    +F  +  G P P+I WF+    I  S+  ++  +    + L
Sbjct: 137 APQFDLEVKDTTVLENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGK-SVL 195

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           +I +    D G   C A N AG AS+   LI+EAP
Sbjct: 196 LIHQTALNDEGEIKCTATNRAGHASTKARLILEAP 230



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 1965 VPSPPTAPLEIRMVGSN---IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
            +P+PP  P+ I     +   +V   W     +GG+ ++GY +  R +    W+       
Sbjct: 29   LPAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLC 88

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
               +  +  L     Y  R+ A+N +GLS P E  +P  V
Sbjct: 89   TFPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTV 128



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 14/127 (11%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-----EGSDIL 652
           LI +  L+D G E+              A ++   PP   + P+ QY D     +   I 
Sbjct: 196 LIHQTALNDEG-EIKCTATNRAGHASTKARLILEAPPKI-RLPR-QYEDGLLFEQDETIR 252

Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
           L+  L   P P + W   GE +  DE ++  +++ +     S+LKI + K+   G Y V 
Sbjct: 253 LKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGE-----SILKIPDAKRVDRGEYVVK 307

Query: 712 AVNREGE 718
           A+N+ GE
Sbjct: 308 AINKLGE 314


>UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=67;
            Euteleostomi|Rep: Myosin-binding protein C, slow-type -
            Homo sapiens (Human)
          Length = 1141

 Score =  172 bits (418), Expect = 1e-40
 Identities = 116/437 (26%), Positives = 202/437 (46%), Gaps = 13/437 (2%)

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            VE+     +V W ++G+ I+P   KY FE +G  R L+I N  + D+ EY     DE C+
Sbjct: 274  VELADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 332

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI--QFSNHIQLT 1155
             E+ V E P  +  +L++     G +   E E+++ DA V+WFK+G EI     +  ++ 
Sbjct: 333  TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIR 392

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
            ++GKK  L I      DA EYS      + +A L+V+   +     L +   V    +  
Sbjct: 393  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD-QTVNLGKEIC 451

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            L  EI  E +   W K    ++++++  ++   +   L+I     +D+ +Y         
Sbjct: 452  LKCEI-SENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510

Query: 1276 TTKLKVEVVEFPPKIV----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKK 1330
            T   KV V++ PPKI+    D +    +  G+ + L +     P P   W    K I++ 
Sbjct: 511  TLPAKVHVID-PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
                +      S++L I   E  D+G+Y + L+N  G A   + V ++D P PP  P + 
Sbjct: 570  SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVT 629

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK--TNSS 1448
            E+      + W+ P   G S I+ Y +E ++  ++ W+ +      +T+ +  K     +
Sbjct: 630  EVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA 689

Query: 1449 YRFRAYAVNEVDISDAS 1465
            Y  R +AVN + IS  S
Sbjct: 690  YEVRIFAVNAIGISKPS 706



 Score =  116 bits (280), Expect = 5e-24
 Identities = 146/647 (22%), Positives = 268/647 (41%), Gaps = 48/647 (7%)

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984
            +   F K L  +Y+ ++G  V    + +   +  KWY N +EI          +G     
Sbjct: 250  KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 309

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
                    D         D++ ST L V+E      ++L+D      +   LE E++ + 
Sbjct: 310  FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 369

Query: 1045 ADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
            A+V W ++G EII   K++Y     G    L I   +  D  EYS +      +A+++V 
Sbjct: 370  ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVD 429

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
              P +I+T L +Q VN G +   + E+++ +   +W K+G  +Q S+ +++   G+  KL
Sbjct: 430  LKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKL 488

Query: 1164 KIYDCDLDDAGEY--SCEVGNSKCTA-ILTVEEPSINFT-LRLPEFILVPANTDAYLTVE 1219
             I +   +D G+Y  + +  N    A +  ++ P I    L     + V A     L + 
Sbjct: 489  VIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 548

Query: 1220 IPDETLDVTWYKK--KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275
            I  E      + +  K+++E + +    S     TL+I     DD   Y   L +   ++
Sbjct: 549  ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608

Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLL-VDYQAFP--QPNDEWIVNSKIIKKC 1331
               +KV+VV+FP P +     E     G D  ++  +  A+    P   + +  K  +  
Sbjct: 609  HASIKVKVVDFPDPPVAPTVTEV----GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664

Query: 1332 KHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
            +  + + D  K  +   KK+    A   ++   N  G +   M        +    P +L
Sbjct: 665  RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLL 724

Query: 1391 EIDS---SSINICWDEPENTGNSTIIYYVVEY------------------QEIDTTEWIS 1429
             +DS   +++ + W  P++ G + +  YV+EY                   ++   +WI 
Sbjct: 725  TVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784

Query: 1430 VKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA---SETTEYYKVIKETKIQSPTV 1484
                 I KT+ +I  L T++    R  AVN    S+    S+     ++I+  KI+ P  
Sbjct: 785  ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 844

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
             K  +       E + L   F G P+P++TW +DG ++   +    N
Sbjct: 845  LK--QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 889



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 55/187 (29%), Positives = 96/187 (51%), Gaps = 6/187 (3%)

Query: 1567 IQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            I + P I I    +KQ +  +VG+   +    +G P PE+ W K+G +++ + + NI   
Sbjct: 833  IIEPPKIRIPRH-LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNS 890

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            E  ++I I++ +RSHS KY ++        +  + +++ D+P  P+  V + ++  E+V 
Sbjct: 891  ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVA 949

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            + W PP DDG   +T Y I+K +  +  W  V +         I +L    EY FRV ++
Sbjct: 950  LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA-TITELVIGNEYYFRVFSE 1008

Query: 1745 NPVGFSE 1751
            N  G SE
Sbjct: 1009 NMCGLSE 1015



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 74/308 (24%), Positives = 142/308 (46%), Gaps = 23/308 (7%)

Query: 1282 EVVEFPPKI--VDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
            E++E PPKI    + ++  I+R G  V L++ +Q  P+P   W  +   I K +    + 
Sbjct: 832  EIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
            ++ +  + I+K E + +G Y L+++ +       +++ I+D+P PP    I ++   ++ 
Sbjct: 891  ETDTI-IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 949

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457
            + W  P++ GN+ I  Y ++  +  + EW +V ++  +T  +I  L   + Y FR ++ N
Sbjct: 950  LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1009

Query: 1458 EVDIS-DASETTEYYKVIKETKI------------QSPTVEKPLKNITTEPNEDIELTCI 1504
               +S DA+ T E   + ++ KI            ++P   +PL N       +  L C 
Sbjct: 1010 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1069

Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATYENRX--XXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P+PK+TW ++   +        + N+                 Y C A ND G VE
Sbjct: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1129

Query: 1561 TSCVVGIQ 1568
              C + ++
Sbjct: 1130 IECKLEVK 1137



 Score = 87.4 bits (207), Expect = 4e-15
 Identities = 60/228 (26%), Positives = 108/228 (47%), Gaps = 11/228 (4%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYT 1644
            G++  +   I G PPP+ +W + G+K   +    I T+    +S + I   +R  S  Y 
Sbjct: 540  GNKLRLEIPISGEPPPKAMWSR-GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYH 598

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            I   N AG +   + +KV D P  P  P +  E+  +   + W+PP  DGG  +  Y IE
Sbjct: 599  INLKNEAGEAHASIKVKVVDFPDPPVAPTVT-EVGDDWCIMNWEPPAYDGGSPILGYFIE 657

Query: 1705 KHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT 1762
            + +  ++RW+++  D+ ++  T+  +K+ E   Y  R+ A N +G S+ ++ S P V   
Sbjct: 658  RKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 716

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
                P+          + + +V + W P +  G + +  Y +E   EG
Sbjct: 717  VTSPPT----LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 87/365 (23%), Positives = 144/365 (39%), Gaps = 19/365 (5%)

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
            V + G ++ V  +  +P   + WY+N + I PS        G    L I N     DS  
Sbjct: 264  VDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYH 962
            Y      +AG       + +    +   K L+ +     G+ V LEC+ S    + KW+ 
Sbjct: 323  YV-----TAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEVSEDDANVKWFK 376

Query: 963  NKKE-ISGMDHREIIQ-EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI 1020
            N +E I G   R  I+ EG+            D      +    ++S  L V     + +
Sbjct: 377  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436

Query: 1021 RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
              L D  V       L+ EI SE     W ++G  ++ + ++     +G I KL I N  
Sbjct: 437  TPLTDQTVNLGKEICLKCEI-SENIPGKWTKNGLPVQ-ESDRLKVVHKGRIHKLVIANAL 494

Query: 1081 VHDEGEYSCILRDESCT--AEVTVVELPPEIITRLQNQK---VNKGNKATFEIELT-KGD 1134
              DEG+Y       + T  A+V V++ P  I+  L       V  GNK   EI ++ +  
Sbjct: 495  TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554

Query: 1135 ALVRWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
                W + D + ++ S  I+         L I   + DD+G Y   + N    A  +++ 
Sbjct: 555  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614

Query: 1194 PSINF 1198
              ++F
Sbjct: 615  KVVDF 619



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 7/132 (5%)

Query: 1929 NIKEKDEI-IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
            +I E+D+  ++ I+ +N  G +      S+++ K    P PP AP  +  VG +  + +W
Sbjct: 587  DIAERDDSGVYHINLKNEAGEA----HASIKV-KVVDFPDPPVAPT-VTEVGDDWCIMNW 640

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              P +DGG+P+LGY I  +    + WM +         F  + + E   Y +RI+A N I
Sbjct: 641  EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700

Query: 2048 GLSEPLESDEPF 2059
            G+S+P     PF
Sbjct: 701  GISKPSMPSRPF 712



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 160/772 (20%), Positives = 262/772 (33%), Gaps = 71/772 (9%)

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            VE+ D  L+V WYK    I  + K+       +R L I  C   D  EY     D K +T
Sbjct: 274  VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCST 333

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHT-K 1335
            +L    V  PP +V  + E       +   L    +    N +W  N + II   K   +
Sbjct: 334  EL---FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
              ++ K   L I+     DA  Y +        A + +++  L K   P     + +   
Sbjct: 391  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL-KILTPLTDQTVNLGKE 449

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
                C       G  T     V  QE D  + +    I K   +    +    Y F   A
Sbjct: 450  ICLKCEISENIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 507

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
             N V +       +  K+I +      TV       T      + L     G P PK  W
Sbjct: 508  YN-VTLPAKVHVIDPPKIILDGLDADNTV-------TVIAGNKLRLEIPISGEPPPKAMW 559

Query: 1516 YRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
             R  K +          +Y +                Y     N+ GE   S  V +   
Sbjct: 560  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619

Query: 1571 PVITISNEDIKQKHKVGDEWLVT----AVIEGIPPPEVIWYKNGNKLENDKEYNITTKE- 1625
            P   ++        +VGD+W +        +G  P  ++ Y    K +    +     + 
Sbjct: 620  PDPPVA----PTVTEVGDDWCIMNWEPPAYDGGSP--ILGYFIERKKKQSSRWMRLNFDL 673

Query: 1626 -KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EISRES 1682
             K +    K++    + +  I A N  G S   +  + +   +    P ++    ++  +
Sbjct: 674  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT 733

Query: 1683 VTIEWKPPLDDGGLELTKYAIE---------KHEPDNNR---------WIKVADVDR-DV 1723
            VT+ W+PP   G   L  Y +E         K   +N           WI VA+ D  D 
Sbjct: 734  VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDK 792

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
              + I  L  + +   RV A N  G SE    S+PI++K  ++ P              +
Sbjct: 793  TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL------K 846

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
              YI       N    +I ++ + + E    K           I+    +T    R   R
Sbjct: 847  QTYIRRVGEAVN---LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 903

Query: 1843 NEIGTSLPYTSDDKITIGKTLT-----PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
            +  G        DK     ++       P  P+   + +    +V L WT P+ +G + I
Sbjct: 904  SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963

Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
            T Y I+    K   W  ++          I  +   +E  FR+ +EN  G+S
Sbjct: 964  TGYTIQKADKKSMEWFTVIEHYHRT-SATITELVIGNEYYFRVFSENMCGLS 1014



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 4/111 (3%)

Query: 491  KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550
            KI K PV+E     + S AP+F + L   +   G      C V G P+P+ITW +    I
Sbjct: 1031 KIYKNPVYE---DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087

Query: 551  KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
                 ++M + +  V TL IR+  P D GT+ C A N  G      +L V+
Sbjct: 1088 VDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 62/281 (22%), Positives = 111/281 (39%), Gaps = 25/281 (8%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVAIESDMHMYCSVLKITNVKKFQE 705
           G  + LEC  V+  + ++ W   GEEI+  P     + +E   H    +L I    K   
Sbjct: 356 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH----ILIIEGATKADA 410

Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
             Y+V+    +  A L + LK       P +++ PL    V  G+ + L  ++  N    
Sbjct: 411 AEYSVMTTGGQSSAKLSVDLK-------PLKILTPLTDQTVNLGKEICLKCEISENIPG- 462

Query: 766 ITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             W KN  PV+    L     G  H + I      +DEG Y   A ++  +    A + V
Sbjct: 463 -KWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVF-APDAYNVT-LPAKVHV 518

Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            +P +   +    ++    +TV     ++L   ++  P P   W R ++ I       + 
Sbjct: 519 IDPPKIILDG---LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575

Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
               +   ++ ++    DSG Y     N AG++    +V +
Sbjct: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 66/245 (26%), Positives = 94/245 (38%), Gaps = 31/245 (12%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            + I  +NE G +    +  K+ +     PP  P    V+E       + W  P  +GGSP
Sbjct: 597  YHINLKNEAGEA---HASIKVKVVDFPDPPVAP---TVTEVGDDWCIMNWEPPAYDGGSP 650

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF--RISAENTVGVSLPTES 1954
            I  Y IE K  +   W ++        E   E  K  + + +  RI A N +G+S P  S
Sbjct: 651  ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP--S 706

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI----------- 2003
               R      V SPPT  L +  V    V   W  P+  G A L GY +           
Sbjct: 707  MPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765

Query: 2004 -------AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
                   A  D+    W+   K  ++  KF I  L  +    +R+ A N  G SEP    
Sbjct: 766  QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825

Query: 2057 EPFKV 2061
            +P  V
Sbjct: 826  QPILV 830



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
            E P   +PL +     G +  L+  V GNP+P ITW KN   +   P         +  L
Sbjct: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1104

Query: 793  KPKKVK--DEGVYTLKAENSEGIAETSAVITVE 823
            + +K    D G Y  KA N  G  E    + V+
Sbjct: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 2/101 (1%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP       + G N+ +T W  P+ DG A + GY I   D     W  V +   +   
Sbjct: 932  PGPPQIVKIEDVWGENVALT-WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTS 989

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
              I +L   + Y  R+++ N  GLSE     +   VI  +G
Sbjct: 990  ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 17/67 (25%), Positives = 31/67 (46%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + G P P++ W KN   + +D  Y + + +    + I++        Y  +A N  GT  
Sbjct: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1129

Query: 1656 VEVTLKV 1662
            +E  L+V
Sbjct: 1130 IECKLEV 1136



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 5/91 (5%)

Query: 733 EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHS 788
           EPP++  P  LK   +R+ GE+V L     G PRP +TW K+   + K      + +T +
Sbjct: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
           I  ++  +    G Y L+ +  +   ET+++
Sbjct: 895 IIFIRKAERSHSGKYDLQVK-VDKFVETASI 924


>UniRef50_Q7ZWM9 Cluster: LOC398550 protein; n=2; Xenopus|Rep:
            LOC398550 protein - Xenopus laevis (African clawed frog)
          Length = 888

 Score =  170 bits (414), Expect = 3e-40
 Identities = 168/694 (24%), Positives = 288/694 (41%), Gaps = 44/694 (6%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+   +  G D++L C L + P   + WL  GEE+V    + + +   +H     L I N
Sbjct: 183  PEQHLLMTGDDLVLTCEL-SRPNFKVRWLRNGEEMVSAGRVKI-LARGVHRQ---LTIQN 237

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILSA 756
            V+    GTYT  A   +   ++ +         E P+V+E    L+++ V +GE+     
Sbjct: 238  VRPADSGTYTCDAGTDQMHTAVYV---------EAPRVVEFVTELQNVTVLEGETASFKC 288

Query: 757  QVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             +V      + W  N  PV   K   T ++G  HS+ IL   ++ D G  T    N+EG+
Sbjct: 289  -MVSPDNVDLRWELNGSPVYSDKRFSTTNNGMCHSL-ILHSCRLSDSGKITA---NAEGL 343

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
              + A + V+E         LF    Q++  +E+  + L  +VTR     I W +   +I
Sbjct: 344  I-SRAKLRVQEAQV------LFAQGLQDMEAEEEQDLLLQVQVTREQA-EIHWVKQGVVI 395

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
             PS   T    G    L I  V +  D G Y C + +   +     R+ +    ++  K 
Sbjct: 396  QPSPKYTLQASGCTHSLTIHGVQAS-DRGRYSCESLHDRTE----CRLNVIPRSISVKKG 450

Query: 934  LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
            L K  +  EG +V    + SH  +  +W+     ++  D   I   GR            
Sbjct: 451  L-KDIKCVEGSSVDFTVEMSHDGLVGEWWKGGVRLTNDDQCTIRSSGRQHFLHLSDLTIP 509

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            D  VI  I     T+  L V E      +  QDF V E   A  + E++ + A V W++D
Sbjct: 510  DSSVIAFITDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGAATFQCEVSRQDATVTWDKD 569

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112
            G  + P      +   G  R L +      D G Y+C + D +  A + V+E  P+++  
Sbjct: 570  GVQLVPNATCRMYSV-GRRRILQLSQCGPSDAGIYTCHMGDINACATLRVLEQEPQMLKD 628

Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            LQ+  + +   A F  E++   A   WFK+G ++Q SN  ++  +G++  L I     +D
Sbjct: 629  LQDVDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVSNTTKIRQEGRRHFLLICGAQCED 688

Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
            AGE + +    + TA L V+E  +     L +   +  +    L  ++      V W + 
Sbjct: 689  AGEITFKARRLQSTARLRVKEIPVRIVKALRDRTALEGHR-VVLECKVNPPRAQVKWLQG 747

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292
               I  + K+ + ++     LII     +D+  YT      + + +L VE +    +I  
Sbjct: 748  GREIFPSAKYQICNEDGFHKLIINDVAPEDEDMYTMSTAGGQCSARLLVEGLAI--QISR 805

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
               + R+K   D     D         +W +N +
Sbjct: 806  GLSDVRVKAPEDACFTCDVSLPLSRPAQWSLNGE 839



 Score =  124 bits (299), Expect = 3e-26
 Identities = 150/685 (21%), Positives = 268/685 (39%), Gaps = 36/685 (5%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + + C L +    D+ WL  G+E+ P ENI +     MH     L+  +++    G 
Sbjct: 99   GDPLSIHCEL-SRNSSDLRWLKDGDEVTPTENIIMEKLGTMH----TLRFLSIQAEDAGQ 153

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y        G  S    +K+              +  ++  G+ ++L+ ++   P   + 
Sbjct: 154  YHC----NVGADSRVFTVKVDDPPVSIVGNTGTPEQHLLMTGDDLVLTCEL-SRPNFKVR 208

Query: 768  WCKNNKP-VKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            W +N +  V A   K  + G    +TI   +   D G YT  A    G  +    + VE 
Sbjct: 209  WLRNGEEMVSAGRVKILARGVHRQLTIQNVRPA-DSGTYTCDA----GTDQMHTAVYVEA 263

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P         F+   Q +TV E  T      V+ + V  + W  N   +   +  +   +
Sbjct: 264  PRVVE-----FVTELQNVTVLEGETASFKCMVSPDNV-DLRWELNGSPVYSDKRFSTTNN 317

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
            G    L++ +     DSG    + +N+ G  S  A++ +   +V F + LQ   E EE +
Sbjct: 318  GMCHSLILHSCRLS-DSGK---ITANAEGLISR-AKLRVQEAQVLFAQGLQ-DMEAEEEQ 371

Query: 945  TVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
             ++L+ Q T       W      I       +   G             D G   C    
Sbjct: 372  DLLLQVQVTREQAEIHWVKQGVVIQPSPKYTLQASGCTHSLTIHGVQASDRGRYSCESLH 431

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
              T   L V        + L+D +  E       VE++ +     W + G +     ++ 
Sbjct: 432  DRTECRLNVIPRSISVKKGLKDIKCVEGSSVDFTVEMSHDGLVGEWWKGG-VRLTNDDQC 490

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
                 G    L++ + ++ D    + I      TA++TV+E P  I    Q+  VN+G  
Sbjct: 491  TIRSSGRQHFLHLSDLTIPDSSVIAFITDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGA 550

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ATF+ E+++ DA V W KDG ++  +   ++   G+++ L++  C   DAG Y+C +G+ 
Sbjct: 551  ATFQCEVSRQDATVTWDKDGVQLVPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMGDI 610

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
               A L V E        L + + +  N +A    E+        W+K    ++ +    
Sbjct: 611  NACATLRVLEQEPQMLKDLQD-VDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVSNTTK 669

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
            +  + ++  L+I     +D  E T      +ST +L+V+  E P +IV   R+     G 
Sbjct: 670  IRQEGRRHFLLICGAQCEDAGEITFKARRLQSTARLRVK--EIPVRIVKALRDRTALEGH 727

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKII 1328
             V L       P+   +W+   + I
Sbjct: 728  RVVLECKVNP-PRAQVKWLQGGREI 751



 Score =   99 bits (238), Expect = 7e-19
 Identities = 125/615 (20%), Positives = 240/615 (39%), Gaps = 38/615 (6%)

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            EG     +C +V+    D+ W   G  +  D+  S          C  L + + +    G
Sbjct: 280  EGETASFKC-MVSPDNVDLRWELNGSPVYSDKRFSTTNNG----MCHSLILHSCRLSDSG 334

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
              T    N EG  S     K++  E +     + L+ M   + + ++L  QV    +  I
Sbjct: 335  KITA---NAEGLISRA---KLRVQEAQV-LFAQGLQDMEAEEEQDLLLQVQVT-REQAEI 386

Query: 767  TWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             W K    ++  P    ++ G THS+TI    +  D G Y+ ++ +       + +    
Sbjct: 387  HWVKQGVVIQPSPKYTLQASGCTHSLTI-HGVQASDRGRYSCESLHDRTECRLNVI---- 441

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
             P   + +  L     ++I   E  ++     ++ + +    W++    ++  +  T   
Sbjct: 442  -PRSISVKKGL-----KDIKCVEGSSVDFTVEMSHDGLVG-EWWKGGVRLTNDDQCTIRS 494

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
             G    L ++  D  I         +++   +   A++T+    +T  +  Q  +   EG
Sbjct: 495  SGRQHFLHLS--DLTIPDSSVIAFITDTLRTT---AQLTVIEHPLTITQPPQ-DFVVNEG 548

Query: 944  KTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
                 +C+ S   +T  W  +  ++       +   GR            D G+  C + 
Sbjct: 549  GAATFQCEVSRQDATVTWDKDGVQLVPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMG 608

Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062
            D      L V E  P+ ++ LQD ++ E + A+   E++   A   W ++GE ++   N 
Sbjct: 609  DINACATLRVLEQEPQMLKDLQDVDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVS-NT 667

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122
                + G    L I      D GE +   R    TA + V E+P  I+  L+++   +G+
Sbjct: 668  TKIRQEGRRHFLLICGAQCEDAGEITFKARRLQSTARLRVKEIPVRIVKALRDRTALEGH 727

Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +   E ++    A V+W + G EI  S   Q+  +    KL I D   +D   Y+     
Sbjct: 728  RVVLECKVNPPRAQVKWLQGGREIFPSAKYQICNEDGFHKLIINDVAPEDEDMYTMSTAG 787

Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEK 1241
             +C+A L VE  +I  +  L + + V A  DA  T ++    +    W      + + E 
Sbjct: 788  GQCSARLLVEGLAIQISRGLSD-VRVKAPEDACFTCDVSLPLSRPAQWSLNGEPLHNEED 846

Query: 1242 FTLISDVKKRTLIIR 1256
             ++ +   +  LI+R
Sbjct: 847  VSIETRGNRHRLILR 861



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 69/266 (25%), Positives = 112/266 (42%), Gaps = 10/266 (3%)

Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
            L V+++     V W +DG  +    N       G  R L +      D GEY C    ES
Sbjct: 12   LVVDVSRSDGRVRWFKDGLEVDEDDN-LQVMSEGLRRCLVLPCAVAEDSGEYICDTDSES 70

Query: 1096 CTAEVTVVELPPEIITR---LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152
             T +V V+E P +I+ R        V  G+  +   EL++  + +RW KDG E+  + +I
Sbjct: 71   ATFDVKVLEPPIKILPRGSSASELNVMAGDPLSIHCELSRNSSDLRWLKDGDEVTPTENI 130

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPA 1210
             +   G    L+      +DAG+Y C VG       + V++P ++       PE  L+  
Sbjct: 131  IMEKLGTMHTLRFLSIQAEDAGQYHCNVGADSRVFTVKVDDPPVSIVGNTGTPEQHLLMT 190

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              D  LT E+      V W +    +    +  +++    R L I+     D   YTC  
Sbjct: 191  GDDLVLTCELSRPNFKVRWLRNGEEMVSAGRVKILARGVHRQLTIQNVRPADSGTYTC-- 248

Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYERE 1296
             DA  T ++   V    P++V++  E
Sbjct: 249  -DA-GTDQMHTAVYVEAPRVVEFVTE 272



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 136/650 (20%), Positives = 246/650 (37%), Gaps = 57/650 (8%)

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
            G +    +++++ D  VRWFKDG E+   +++Q+  +G ++ L +     +D+GEY C+ 
Sbjct: 7    GERVQLVVDVSRSDGRVRWFKDGLEVDEDDNLQVMSEGLRRCLVLPCAVAEDSGEYICDT 66

Query: 1181 GNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
             +   T  + V EP I    R      + V A     +  E+   + D+ W K    +  
Sbjct: 67   DSESATFDVKVLEPPIKILPRGSSASELNVMAGDPLSIHCELSRNSSDLRWLKDGDEVTP 126

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIV---DYE 1294
            TE   +       TL       +D  +Y C V  D++  T   V+V + P  IV      
Sbjct: 127  TENIIMEKLGTMHTLRFLSIQAEDAGQYHCNVGADSRVFT---VKVDDPPVSIVGNTGTP 183

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
             ++ +  G D+ L  +    P     W+ N + +      K         LTI+ V   D
Sbjct: 184  EQHLLMTGDDLVLTCELSR-PNFKVRWLRNGEEMVSAGRVKILARGVHRQLTIQNVRPAD 242

Query: 1355 AGIYKLRLENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
            +G Y      +  H  V +    +++  +      +LE +++S   C   P+N      +
Sbjct: 243  SGTYTCDAGTDQMHTAVYVEAPRVVEFVTELQNVTVLEGETASFK-CMVSPDNVD----L 297

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             + +    + + +  S  N     + I  + + + S +  A A  E  IS A    +  +
Sbjct: 298  RWELNGSPVYSDKRFSTTNNGMCHSLILHSCRLSDSGKITANA--EGLISRAKLRVQEAQ 355

Query: 1473 VIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGV---PQPKVTWYRDGKKLKTAKA 1527
            V+    +Q      E+ L        E  E+  +  GV   P PK T       L+ +  
Sbjct: 356  VLFAQGLQDMEAEEEQDLLLQVQVTREQAEIHWVKQGVVIQPSPKYT-------LQASGC 408

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKV 1586
            T+                  Y C + +D     T C + +  + + +    +DIK     
Sbjct: 409  TH----SLTIHGVQASDRGRYSCESLHD----RTECRLNVIPRSISVKKGLKDIKCVEGS 460

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK---Y 1643
              ++ V    +G+      W+K G +L ND +  I +  +   + + +L    SS     
Sbjct: 461  SVDFTVEMSHDGLVGE---WWKGGVRLTNDDQCTIRSSGRQHFLHLSDLTIPDSSVIAFI 517

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSK---PEG--PVIMREISRESVTIEWKPPLDDGGLEL 1698
            T     TA  + +E  L +   P      EG       E+SR+  T+ W    D  G++L
Sbjct: 518  TDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGAATFQCEVSRQDATVTW----DKDGVQL 573

Query: 1699 TKYA-IEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNP 1746
               A    +     R ++++     D   Y     + N     RV+ Q P
Sbjct: 574  VPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMGDINACATLRVLEQEP 623



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 2/70 (2%)

Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
           V+ LR +   +G  V  EC+V   PR Q+ W +    I PS  +Q+  ++D    L+I +
Sbjct: 715 VKALRDRTALEGHRVVLECKVNP-PRAQVKWLQGGREIFPSAKYQI-CNEDGFHKLIIND 772

Query: 573 VFPEDAGTFT 582
           V PED   +T
Sbjct: 773 VAPEDEDMYT 782


>UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - Aedes
            aegypti (Yellowfever mosquito)
          Length = 2679

 Score =  170 bits (414), Expect = 3e-40
 Identities = 155/601 (25%), Positives = 266/601 (44%), Gaps = 58/601 (9%)

Query: 459  QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518
            QK + E    V  + + +E +  +  Q+ + E   K+   +    +++   P F+EKL+ 
Sbjct: 1554 QKRVQEVTDKVAEESVREEQHILESTQQTVAET--KIQEQKIKVKKQKVQPPSFIEKLQS 1611

Query: 519  KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            +       V  +C++EG P P++ WF    ++  + ++ M   +D VATL I  V P   
Sbjct: 1612 QICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIVED-VATLEIATVMPYHV 1670

Query: 579  GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
            G +TC AKN AG A S   ++V+A       E+                   G  PTF  
Sbjct: 1671 GVYTCEAKNVAGVALSKANIVVQAK-----PEV-------------------GEAPTFIT 1706

Query: 639  KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI-SVAIESDMHMYCSVLKI 697
              K    ++ +   + C++  IP P + W    EEI+  E I +V IE   H+  +V K 
Sbjct: 1707 PLKISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKK- 1765

Query: 698  TNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK-EP----PQVIEPLKSMIVRQGE 750
               K+     YT+ A N+ G+A     + ++  T EK +P    P+++EPL++ +V+ G 
Sbjct: 1766 --PKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGS 1823

Query: 751  SVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            +++   +  G P+PT+ W +N+K V  +   T    + +S  ++     K  G Y +   
Sbjct: 1824 TLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVH 1883

Query: 809  NSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            N  G A++SA +T+ + +E + A+ P F+       V E     L A V   P  +  W+
Sbjct: 1884 NEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWF 1943

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV----TI 923
            R    I  S    +    EN  ++I    ++ D G Y C A N AG  +  A V    TI
Sbjct: 1944 REGAAIKSSNE-QRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETI 2002

Query: 924  DVEKVT------FVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975
            + E+VT      F++ + K     +G+ +IL CQ   +     +WYHN++ I     ++ 
Sbjct: 2003 ETEEVTEYISPRFIEPI-KPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQF 2061

Query: 976  IQEGRXX-XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKD 1032
             Q+               D G   CI  ++  E      V     E++   + F   E+D
Sbjct: 2062 QQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRSSEED 2121

Query: 1033 V 1033
            +
Sbjct: 2122 L 2122



 Score =  140 bits (338), Expect = 5e-31
 Identities = 126/492 (25%), Positives = 211/492 (42%), Gaps = 40/492 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F +K ++Q  +    +LL+C++  IP P++ W F    +  +    + I  D+    
Sbjct: 1602 PPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIVEDV---- 1657

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            + L+I  V  +  G YT  A N  G A     IV++ K    E P  I PLK  +     
Sbjct: 1658 ATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNEDKT 1717

Query: 751  SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDT-H-SITILKPKKVKDEGVYTL 805
               ++ QV G P P + W ++ +    ++ + T    +T H  +T+ KPK+     +YT+
Sbjct: 1718 VATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ-NVPILYTI 1776

Query: 806  KAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTRNPV 861
            +AEN  G A   A + ++  T E  +P    P  +   Q   VK   T+    R T  P 
Sbjct: 1777 QAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPK 1836

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            P++ W+RN++ +   E +T   +    ++VIT +  +  SG Y+ +  N AG +   A V
Sbjct: 1837 PTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKK-RSGKYEIIVHNEAGDAKSSASV 1895

Query: 922  TI-------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHR 973
            TI       + +   FV+ L      E    ++     S+  ST +W+     I   + +
Sbjct: 1896 TISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNEQ 1955

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKC---IVKDQETSTMLV-VKETI----------PEF 1019
             I+ +              DVG   C    V    TST  V V ETI          P F
Sbjct: 1956 RIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETEEVTEYISPRF 2015

Query: 1020 IRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
            I  ++   V + +  IL  +++ +    V W  + ++I   K+K   +       L +  
Sbjct: 2016 IEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQQDSSGRCVLTVSE 2075

Query: 1079 TSVHDEGEYSCI 1090
                D GEY+CI
Sbjct: 2076 VFPEDTGEYACI 2087



 Score =  120 bits (290), Expect = 3e-25
 Identities = 105/369 (28%), Positives = 159/369 (43%), Gaps = 38/369 (10%)

Query: 497  VFEKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            V E   +EE  + ++P F+E ++P    DG  +   CQV   P P++ W+    +I  ++
Sbjct: 1998 VLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETK 2057

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----APLSD--HG 608
            D Q   D      L + EVFPED G + C+A N  G A   T + VE     P S+    
Sbjct: 2058 DKQFQQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRS 2117

Query: 609  SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
            SE  +            A+ +E  P    + P+    +E     LE +++A P+  I WL
Sbjct: 2118 SEEDLLTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRWL 2177

Query: 669  FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLK 726
               EEI+P E   +    D     S+L I ++     GT T  A N  G A  +  +V++
Sbjct: 2178 KANEEIIPSEEFQIENFED---GTSILVINDIYPDDSGTITFEAHNALGVATTTTELVVE 2234

Query: 727  IKTGEK-----EPPQVIEPLK------------SMIVRQ-----GESVILSAQVVGNPRP 764
               G K     E  Q +E +K            SM ++      GE         GNP+P
Sbjct: 2235 EHVGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRAMLGEKGFFECHFAGNPKP 2294

Query: 765  TITWCKNNKPVKALP-TKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             I W +N K + A    K   + HS T I+ P + +D G Y  +A +  G  E+ A + +
Sbjct: 2295 DILWYRNGKIIIANERVKICIEEHSATLIIYPVEFEDFGFYKCRAMSDAGSCESYAKL-I 2353

Query: 823  EEPTEENAE 831
            E  TE   E
Sbjct: 2354 ESTTETLTE 2362



 Score =  117 bits (281), Expect = 4e-24
 Identities = 128/479 (26%), Positives = 193/479 (40%), Gaps = 85/479 (17%)

Query: 502  TSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            TSE +++ AP FVE L PK   +      E  V+ YP     WFR+ A IK S + Q   
Sbjct: 1900 TSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNE-QRIV 1958

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
             D+N + L+I      D G +TC A+N AG  +ST  + V   +                
Sbjct: 1959 TDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETE------------- 2005

Query: 621  XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
                  ++ E I P F +  K   V +G  ++L C++ A P P + W    + IV  E  
Sbjct: 2006 ------EVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIV--ETK 2057

Query: 681  SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN-------------------------R 715
                + D    C VL ++ V     G Y  +A N                         R
Sbjct: 2058 DKQFQQDSSGRC-VLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFR 2116

Query: 716  EGEASLPIVLKIKTGEK--EP----PQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITW 768
              E  L     I T E+  EP    PQ+++ L  +I+ +   +  L  +V+  P+  I W
Sbjct: 2117 SSEEDLLTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRW 2176

Query: 769  CKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
             K N+   P +    ++  D  SI ++      D G  T +A N+ G+A T+  + VEE 
Sbjct: 2177 LKANEEIIPSEEFQIENFEDGTSILVINDIYPDDSGTITFEAHNALGVATTTTELVVEEH 2236

Query: 826  TEENA---------------------EPPLFINRFQE--ITVKEKGTIKLVARVTRNPVP 862
                A                      PP F    ++    + EKG  +       NP P
Sbjct: 2237 VGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRAMLGEKGFFE--CHFAGNPKP 2294

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             I WYRN +II  +E +    +  +  L+I  V+ E D G YKC A + AG     A++
Sbjct: 2295 DILWYRNGKIIIANERVKICIEEHSATLIIYPVEFE-DFGFYKCRAMSDAGSCESYAKL 2352



 Score =  112 bits (269), Expect = 1e-22
 Identities = 134/533 (25%), Positives = 219/533 (41%), Gaps = 76/533 (14%)

Query: 432  ETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEK 491
            + +E I + E E +YI +T      +++  + + K  VP  Y +   N       K N  
Sbjct: 1738 DEEEIIEIEEIETVYIEETG-----HIKLTVKKPKQNVPILYTIQAENKFGKAVGKANLF 1792

Query: 492  IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
            I  + + EKP  E   +AP  VE L+ +    GST+ FEC+  G P+P + WFR +  + 
Sbjct: 1793 IQSITI-EKPKPE--MIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVV 1849

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
              ++  +   ++  + +VI ++  + +G +  +  N AG A S+  + +    SD  SEM
Sbjct: 1850 EEEEVTI-VTEEYYSKIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTI----SD-TSEM 1903

Query: 612  TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671
                              E   P F +    + V E    +LE  + + P     W  +G
Sbjct: 1904 D-----------------EAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREG 1946

Query: 672  EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE----ASLPIVLKI 727
              I       +  + +     S+L I +  K   G YT  A N  G     A++ ++  I
Sbjct: 1947 AAIKSSNEQRIVTDENK----SILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETI 2002

Query: 728  KTGEKE---PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-D 783
            +T E      P+ IEP+K   V  GE +IL+ QV   P P + W  N + +     K   
Sbjct: 2003 ETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQ 2062

Query: 784  GDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE------------------ 823
             D+    +L   +V  +D G Y   A N  G A     + VE                  
Sbjct: 2063 QDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRSSEEDL 2122

Query: 824  ------EPTEENAEP----PLFINRFQEITVKEKGTI-KLVARVTRNPVPSITWYRNNEI 872
                     EE AEP    P  + +  E+ + E+  + KL  +V   P   I W + NE 
Sbjct: 2123 LTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRWLKANEE 2182

Query: 873  ISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            I PSE    +NF+     LVI ++  + DSG     A N+ G ++    + ++
Sbjct: 2183 IIPSEEFQIENFEDGTSILVINDIYPD-DSGTITFEAHNALGVATTTTELVVE 2234



 Score =  111 bits (267), Expect = 2e-22
 Identities = 130/517 (25%), Positives = 217/517 (41%), Gaps = 54/517 (10%)

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784
            +K+K  + +PP  IE L+S I    + V+L  ++ G P P + W  N+  + A P     
Sbjct: 1593 IKVKKQKVQPPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMN 1652

Query: 785  DTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
                +  L+   V     GVYT +A+N  G+A + A I V+   E   E P FI    +I
Sbjct: 1653 IVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEV-GEAPTFITPL-KI 1710

Query: 843  TVKEKGTIKLV-ARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIELVITNVDSEI 899
            +V E  T+  V  +V   P+P + W+R+ E I   E I   +  E  +I+L +      +
Sbjct: 1711 SVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNV 1770

Query: 900  DSGDYKCVASNSAGKSSHGARV---TIDVEK-------VTFVKHLQKSYETEEGKTVILE 949
                Y   A N  GK+   A +   +I +EK          V+ LQ +   + G T++ E
Sbjct: 1771 PI-LYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQ-AQVVKSGSTLVFE 1828

Query: 950  CQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----D 1003
            C+ +     + KW+ N KE+   +   I+ E                G  + IV     D
Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888

Query: 1004 QETSTMLVVKET-------IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEI 1055
             ++S  + + +T        P F+  L    V E +V ILE  ++S  T+   W R+G  
Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAA 1948

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVE------- 1104
            IK   N+       +   L I + +  D G Y+C    +    + TA V V+E       
Sbjct: 1949 IK-SSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETEEV 2007

Query: 1105 ---LPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGK- 1159
               + P  I  ++  +V  G K     ++       V+W+ +   I  +   Q   D   
Sbjct: 2008 TEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQQDSSG 2067

Query: 1160 KQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
            +  L + +   +D GEY+C    ++G + C   + VE
Sbjct: 2068 RCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVE 2104



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 63/220 (28%), Positives = 102/220 (46%), Gaps = 12/220 (5%)

Query: 470  PAQYLMDENNYTQYLQKKLNEK-IDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTV 527
            P +Y+ D   +    +  L +K I  L  + +P       AP  V++L     + +    
Sbjct: 2105 PFEYVPDSEQFRSSEEDLLTDKSISTLEEYAEPIE----YAPQIVKQLPEVIMSEERQLT 2160

Query: 528  QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
            + E +V   P+ QI W +    I PS++FQ+   +D  + LVI +++P+D+GT T  A N
Sbjct: 2161 KLEVKVLAQPKAQIRWLKANEEIIPSEEFQIENFEDGTSILVINDIYPDDSGTITFEAHN 2220

Query: 588  AAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYV 645
            A G A++TTEL+VE    +H                   + L+    PP+FS + K    
Sbjct: 2221 ALGVATTTTELVVE----EHVGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRA 2276

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
              G     EC     P+PDI W   G+ I+ +E + + IE
Sbjct: 2277 MLGEKGFFECHFAGNPKPDILWYRNGKIIIANERVKICIE 2316



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 153/709 (21%), Positives = 285/709 (40%), Gaps = 77/709 (10%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            +E P V+E +  ++    E + L  + V   +P     + NK V     K +  T+ I  
Sbjct: 1409 EELPHVVETIADIVPE--EVLELIPEEVPLEKPKKRKSRTNKHVVF---KEELSTYEI-- 1461

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQ-EITVKEKGT 849
             +P+ VKDE     + E  E + +  +  T++ +PTE     PL I     E  ++E+  
Sbjct: 1462 -QPEVVKDEEE---EEEEEEEVQQEVSQKTIQLKPTEVTEVKPLPIESIPIEEIMEEQSE 1517

Query: 850  IK--LVARVTRNPVPSI---TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
             +  +  ++  N V       +  +++ +   E ITQ    E  + V      E +    
Sbjct: 1518 FRKEMAVKIQSNIVKKEKRRVFVDDSQPLPELEIITQKRVQEVTDKVAEESVRE-EQHIL 1576

Query: 905  KCVASNSAGKSSHGARVTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHTV--STK 959
            +      A       ++ +  +KV   +F++ LQ S   E  + V+L+C+         +
Sbjct: 1577 ESTQQTVAETKIQEQKIKVKKQKVQPPSFIEKLQ-SQICEPNQPVLLQCKIEGIPFPEVR 1635

Query: 960  WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD------QETSTMLVVK 1013
            W+ N   +       +                  VGV  C  K+       + + ++  K
Sbjct: 1636 WFFNDTVLFANPEYVMNIVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAK 1695

Query: 1014 ETI---PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE-IIKPKKNKYDF-EK 1067
              +   P FI  L+    ++K VA +  +++      V W RD E II+ ++ +  + E+
Sbjct: 1696 PEVGEAPTFITPLKISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEE 1755

Query: 1068 RGHIRKLYIRNT--------SVHDEGEYSCILRDESCTAEVTVVELP------PEIITRL 1113
             GHI KL ++          ++  E ++   +   +   +   +E P      P+I+  L
Sbjct: 1756 TGHI-KLTVKKPKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPL 1814

Query: 1114 QNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            Q Q V  G+   FE   T      V+WF++  E+     + +  +    K+ I       
Sbjct: 1815 QAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKR 1874

Query: 1173 AGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LVP---ANTDAYLTVEIPDE 1223
            +G+Y      E G++K +A +T+ + S     + P F+  L P   A  +  +   + D 
Sbjct: 1875 SGKYEIIVHNEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDS 1934

Query: 1224 --TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKSTT 1277
              T    W+++ + I+ + +  +++D  K  LII    + D   YTC    V     ST 
Sbjct: 1935 YPTSTFQWFREGAAIKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTA 1994

Query: 1278 KLKV-------EVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
             ++V       EV E+  P+ ++  +  R+  G  + L     A P P  +W  N ++I 
Sbjct: 1995 TVQVLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIV 2054

Query: 1330 KCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            + K  +   DS     LT+ +V   D G Y     N  G A  +  V +
Sbjct: 2055 ETKDKQFQQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNV 2103



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 83/412 (20%), Positives = 160/412 (38%), Gaps = 30/412 (7%)

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            K+K + V+ PP  ++  +    +    V L    +  P P   W  N  ++        +
Sbjct: 1594 KVKKQKVQ-PPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMN 1652

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397
            I    A+L I  V     G+Y    +N  G A  + N+ +  KP     P  +     S+
Sbjct: 1653 IVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISV 1712

Query: 1398 NICWDEPENTGNSTIIYYVV------------EYQEIDTTEWISVKNITKTQTSIQNLKT 1445
            N    E +     T   + +            E  EI+  E + ++     + +++  K 
Sbjct: 1713 N----EDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ 1768

Query: 1446 NSSYRFRAYAVNEVD--ISDASETTEYYKVIK-ETKIQSPTVEKPLKNITTEPNEDIELT 1502
            N    +   A N+    +  A+   +   + K + ++ +P + +PL+    +    +   
Sbjct: 1769 NVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFE 1828

Query: 1503 CIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            C F GVP+P V W+R+ K++    +    T E                 Y+ I  N+ G+
Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888

Query: 1559 VETSCVVGIQQKPVITISN-----EDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNK 1612
             ++S  V I     +  +      E +  K     E  ++ AV++  P     W++ G  
Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAA 1948

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
            +++  E  I T E  S++ I+   +     YT  A N AG+ +   T++V +
Sbjct: 1949 IKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLE 2000



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 66/286 (23%), Positives = 122/286 (42%), Gaps = 22/286 (7%)

Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV- 1473
            +V + Q +   E I+ K + +    +       S R   + +     + A    +  K+ 
Sbjct: 1539 FVDDSQPLPELEIITQKRVQEVTDKV----AEESVREEQHILESTQQTVAETKIQEQKIK 1594

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATY 1529
            +K+ K+Q P+  + L++   EPN+ + L C   G+P P+V W+ +   L    +      
Sbjct: 1595 VKKQKVQPPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIV 1654

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGD 1588
            E+                Y C A N  G   +   + +Q KP +  +   I   K  V +
Sbjct: 1655 EDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNE 1714

Query: 1589 EWLVTAV---IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKY 1643
            +  V  V   + GIP P+V W+++  ++   +E      E+T  I+  +K+ K++    Y
Sbjct: 1715 DKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNVPILY 1774

Query: 1644 TIEASNTAGTSSVEVTLKV----YDKPSKPE--GPVIMREISRESV 1683
            TI+A N  G +  +  L +     +KP KPE   P I+  +  + V
Sbjct: 1775 TIQAENKFGKAVGKANLFIQSITIEKP-KPEMIAPKIVEPLQAQVV 1819



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 62/272 (22%), Positives = 109/272 (40%), Gaps = 19/272 (6%)

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPL 1488
            V NI +   +++ + T   Y    Y     +++  + +     V  + ++ ++PT   PL
Sbjct: 1650 VMNIVEDVATLE-IATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPL 1708

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXXXXXXXXX 1542
            K    E      +TC   G+P PKV W+RD +++      +T                  
Sbjct: 1709 KISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ 1768

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVITISN--EDIK-QKHKVGDEWLVT 1593
                 Y   A N  G+      + IQ       KP +      E ++ Q  K G   +  
Sbjct: 1769 NVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFE 1828

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG- 1652
                G+P P V W++N  ++  ++E  I T+E  S I I ++ +  S KY I   N AG 
Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888

Query: 1653 -TSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
              SS  VT+    +  + + P  +  ++ + V
Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLV 1920



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 85/421 (20%), Positives = 157/421 (37%), Gaps = 30/421 (7%)

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            L  A    + K EV E P  I   +      + +  T+       P P   W  + + I 
Sbjct: 1685 LSKANIVVQAKPEVGEAPTFITPLKISVNEDK-TVATVTCQVHGIPMPKVRWFRDEEEII 1743

Query: 1330 KCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI----LDKPSP 1383
            + +  +     ++    LT+KK +     +Y ++ EN  G A  + N+ I    ++KP P
Sbjct: 1744 EIEEIETVYIEETGHIKLTVKKPKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKP 1803

Query: 1384 PG-KPNILE------IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
                P I+E      + S S  +           T+ ++    + ++  E   V     +
Sbjct: 1804 EMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYS 1863

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
            +  I  +    S ++     NE   + +S +       +  + ++P   +PL        
Sbjct: 1864 KIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEA 1923

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552
            E   L  +    P     W+R+G  +K++      T EN+               Y C A
Sbjct: 1924 EVCILEAVVDSYPTSTFQWFREGAAIKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRA 1983

Query: 1553 FNDHGEVETSCVVG----IQQKPVITISN----EDIKQKHKVGDEWLVTAV-IEGIPPPE 1603
             N  G V ++  V     I+ + V    +    E IK    +  E L+ A  +   P P+
Sbjct: 1984 ENVAGSVTSTATVQVLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPK 2043

Query: 1604 VIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            V WY N   +    DK++   +  +  V+ + E+    + +Y   ASN  G +  + T+ 
Sbjct: 2044 VQWYHNEQLIVETKDKQFQQDSSGR-CVLTVSEVFPEDTGEYACIASNKLGEAICKTTVN 2102

Query: 1662 V 1662
            V
Sbjct: 2103 V 2103



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 84/403 (20%), Positives = 154/403 (38%), Gaps = 45/403 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P FI KLQ    +     +L+ +I      +V W  +  ++     +Y       +  L 
Sbjct: 1603 PSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANP-EYVMNIVEDVATLE 1661

Query: 1076 IRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEI------ITRLQNQKVNKGNKATF 1126
            I     +  G Y+C  ++ +  A      VV+  PE+      IT L+         AT 
Sbjct: 1662 IATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNEDKTVATV 1721

Query: 1127 EIELTKGDAL--VRWFKDGSEI-----------QFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
              ++  G  +  VRWF+D  EI           + + HI+LT+   KQ + I    +   
Sbjct: 1722 TCQV-HGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNVPIL-YTIQAE 1779

Query: 1174 GEYSCEVGNSKC-TAILTVEEPSINFTL-RLPEFILVPA-NTDAYLTVE-----IPDETL 1225
             ++   VG +      +T+E+P       ++ E +      + + L  E     +P  T 
Sbjct: 1780 NKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPT- 1838

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKV 1281
             V W++    + + E+ T++++     ++I K T+    +Y  ++     DAKS+  + +
Sbjct: 1839 -VKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTI 1897

Query: 1282 ----EVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
                E+ E   P+ V+      +       L     ++P    +W      IK     + 
Sbjct: 1898 SDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNEQRI 1957

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
              D   + L I+     D G Y  R EN  G       V +L+
Sbjct: 1958 VTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLE 2000



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/84 (29%), Positives = 36/84 (42%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP      ++ R   G        +   P+P+  W  N KII   +  K  I+  SA+L 
Sbjct: 2264 PPSFSMEIKDSRAMLGEKGFFECHFAGNPKPDILWYRNGKIIIANERVKICIEEHSATLI 2323

Query: 1347 IKKVENTDAGIYKLRLENNCGHAD 1370
            I  VE  D G YK R  ++ G  +
Sbjct: 2324 IYPVEFEDFGFYKCRAMSDAGSCE 2347



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 57/250 (22%), Positives = 98/250 (39%), Gaps = 17/250 (6%)

Query: 158  LFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPD--DK 215
            L + +  E   +V QP     ++ K   +  EE + P  K   +  E  E++ +     K
Sbjct: 828  LIEEKPAEPIVEVEQPTWRRTKKPKPVEEETEEKKWPTGKRRPLPEEPKEEVTLKPIPKK 887

Query: 216  ETSQTPTSFNKRS-KLTP---IKIERKEMEVSTPQHAETVDG--PQFXXXXXXXXXXXXX 269
            E ++ P    + + K TP   I  E KE E++    A+  +   P +             
Sbjct: 888  EKAEEPKPTKEPTIKPTPLPEIPDEPKEEEITIQPPAQEDESHLPPWRRGKKPAQKREIP 947

Query: 270  XETSLVKLPKFQLKSRIKYITSWPPE-----SIKPLISYMGSIKQNGILSRNIKEAAKVK 324
                   + + +LK   K     P E     S+KP +     + +  +L   + E  ++K
Sbjct: 948  KPAEPEAMEQIKLKPTPKVKKEIPKEALEEVSLKP-VPKQPEVAEAVVLEPEVSEVKEIK 1006

Query: 325  KQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITP 384
                  PK P  E   LE+P+F   +I E +    E I++   + E P+E  PEQ +   
Sbjct: 1007 ITKPKEPK-PKREIEPLEKPVFP--EIPEPEPVVLEEIEKVLEVVEKPEEPAPEQPSWRR 1063

Query: 385  RKSSAQKIDE 394
             K     +DE
Sbjct: 1064 EKKPKPVVDE 1073


>UniRef50_UPI00015A4170 Cluster: eEF1A2 binding protein; n=1; Danio
            rerio|Rep: eEF1A2 binding protein - Danio rerio
          Length = 928

 Score =  170 bits (413), Expect = 4e-40
 Identities = 168/768 (21%), Positives = 312/768 (40%), Gaps = 41/768 (5%)

Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE--INSETADVVWERDGEII-----KPKKNKYDFEKR 1068
            + E +  ++  EVK    A  E +  I    + +   ++GE++          K++ +K 
Sbjct: 57   VVENVDNMKPIEVKTSGRAEFEFDMRIKDPNSKIYMYKNGEMLDYGAGSDDTCKHNMKKT 116

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP-EIITRLQNQKVNKGNKATFE 1127
            G      I N  ++D G Y   + D +     T +E+P  E   +L++ KV +G  A FE
Sbjct: 117  GDKYLFSINNLGLNDGGLYQVDVDDVNIIT--TKLEVPDVEFDGKLKDVKVVEGQDAVFE 174

Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGNSKC 1185
               +   + + W  +   ++  +   +T+   K   +L + +   +D G Y+   G    
Sbjct: 175  GVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAGIKSS 234

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245
             A L V +  ++F   L +   +     A L  ++  + ++  WYK  + +   +   + 
Sbjct: 235  RASLAVNDDKLHFASGLTDKNALRGKP-AELVCKLSTDKINGVWYKDGNKLTSKDGVVIS 293

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD----YEREYRIKR 1301
             D     L+++ C + D   Y   +   K+   ++V +++ P   +D    +     +K 
Sbjct: 294  KDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDLDALGKFSNPVIVKA 353

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
            G   +  + +   P    +W  N   +      K   +S  + L IK    +D G  ++R
Sbjct: 354  GQSASFKMSFPPQPSLEIKWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIR 413

Query: 1362 LENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
            L+N  G  +   ++T+ DKP PP G   + E  SS + + W+ P++ G S +  Y++E  
Sbjct: 414  LKNPFGSIEALSSLTVQDKPGPPQGPVEVNETTSSVLELKWNPPKDEGGSAVTNYIIEQL 473

Query: 1421 EIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKE 1476
            ++    W  V +I     +   +++     Y +R YA N   IS+A ET +     ++  
Sbjct: 474  QVGQNTWQKVGDIPANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKIMAGSLMFP 533

Query: 1477 TKIQSPTVEKPLK---NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
                 P V    K   N++  P E      I G   + +         L + K   +   
Sbjct: 534  GPPTQPKVVSAFKNCINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKG-L 592

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKPVITISNEDIKQKHKVG 1587
                          ++ IA N  G  E S      C      KP      ED     + G
Sbjct: 593  KYGVKDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFK-DPEDF-MVVRSG 650

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
            +   +    E  P P++ W KNG  +    +  I   + T  + +   K S S  YTI A
Sbjct: 651  NSIRIKINYEAAPQPDIKWLKNGEPVSPWNK--IIHDDGTCTLIVPSSKYSDSGVYTIVA 708

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
             N++G +S ++  +  D+P +P GPV + ++    V I W P  D    +   Y +E+  
Sbjct: 709  KNSSGQASFDI--EFIDEP-RPPGPVELEQLVFGKVIIRWLPSPDHDRDDRLHYMVEEQN 765

Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
             ++  W  +A  D  + T     +    EY FR+ A+N +G S+  +S
Sbjct: 766  SNSRIWRTIA--DHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811



 Score =  159 bits (385), Expect = 1e-36
 Identities = 121/464 (26%), Positives = 211/464 (45%), Gaps = 27/464 (5%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P  E+ W+KNG++L +     +  +   S ++IK+  RS + +  I   N  G+     +
Sbjct: 367  PSLEIKWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSS 426

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
            L V DKP  P+GPV + E +   + ++W PP D+GG  +T Y IE+ +   N W KV D+
Sbjct: 427  LTVQDKPGPPQGPVEVNETTSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDI 486

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
              +   +  + ++    Y++R+ A+NP G SEALE+E I +  +L  P            
Sbjct: 487  PANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKI-MAGSLMFPGPPTQPKVVSAF 545

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX----XXXXXARIQKLSINTT 1834
             N  + ++W P EK+GG+ I+ Y++E  K++  +W                ++ +S  + 
Sbjct: 546  KN-CINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSE 604

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEPESN 1892
            Y+FR+ A N  G   P T  + +        P    P +F+V  S   S+ +K     + 
Sbjct: 605  YEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFKDPEDFMVVRS-GNSIRIKINYEAA- 662

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
               P   ++   + V    W KI+   G+     + + K  D  ++ I A+N+ G     
Sbjct: 663  -PQPDIKWLKNGEPV--SPWNKIIHDDGTC-TLIVPSSKYSDSGVYTIVAKNSSG----- 713

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW-GTPEWDGGAPLLGYNIAIRDVTKT 2011
               S  +E     P PP  P+E+  +    V+  W  +P+ D     L Y +  ++    
Sbjct: 714  -QASFDIE-FIDEPRPP-GPVELEQLVFGKVIIRWLPSPDHDRD-DRLHYMVEEQNSNSR 769

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            +W  +   D          +     Y  RIYA+N++GLS+P +S
Sbjct: 770  IWRTI--ADHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811



 Score =  124 bits (300), Expect = 2e-26
 Identities = 121/551 (21%), Positives = 229/551 (41%), Gaps = 47/551 (8%)

Query: 1003 DQETSTMLVVKETIP--EFIRKLQDFEVKEKDVAILEVEINSETADVVW-ERDGEIIKPK 1059
            D +   ++  K  +P  EF  KL+D +V E   A+ E   +   + + W   D  +    
Sbjct: 138  DVDDVNIITTKLEVPDVEFDGKLKDVKVVEGQDAVFEGVFSGPVSQITWCVNDISVEHGD 197

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
            K      +     +L ++N+   D G Y+ I   +S  A + V +      + L ++   
Sbjct: 198  KYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAGIKSSRASLAVNDDKLHFASGLTDKNAL 257

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            +G  A    +L+       W+KDG+++   + + ++ DG   KL + +C   DAG Y  E
Sbjct: 258  RGKPAELVCKLSTDKINGVWYKDGNKLTSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFE 317

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEF-----------ILVPANTDAYLTVEIPDE-TLDV 1227
            V   K  A++ V      F L LPEF           ++V A   A   +  P + +L++
Sbjct: 318  VNGCKTEAMVRV------FLLDLPEFDLDALGKFSNPVIVKAGQSASFKMSFPPQPSLEI 371

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEV 1283
             W+K  S + D     ++ +     L I+ C   D  +    L +     ++ + L V+ 
Sbjct: 372  KWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSSLTVQD 431

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC---KHTKPSIDS 1340
               PP     +    +   +   L + +   P+      V + II++    ++T   +  
Sbjct: 432  KPGPP-----QGPVEVNETTSSVLELKWNP-PKDEGGSAVTNYIIEQLQVGQNTWQKVGD 485

Query: 1341 KSASLTIKKVENTDAG---IYKLRLENNCGHADV----EMNVTILDKPSPPGKPNILEID 1393
              A+    +  +   G   IY++  EN  G ++     ++    L  P PP +P ++   
Sbjct: 486  IPANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKIMAGSLMFPGPPTQPKVVSAF 545

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKN-ITKTQTSIQNLKTNSSY 1449
             + IN+ W  PE  G + I+ Y +E ++ DT +W+   SVK+ I   +  ++++   S Y
Sbjct: 546  KNCINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEY 605

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             FR  A+N     + S  +E   V  +     P  + P   +       I +   +   P
Sbjct: 606  EFRVIAINSSGAGEPSTPSE--MVCAKNPNMKPHFKDPEDFMVVRSGNSIRIKINYEAAP 663

Query: 1510 QPKVTWYRDGK 1520
            QP + W ++G+
Sbjct: 664  QPDIKWLKNGE 674



 Score =  124 bits (299), Expect = 3e-26
 Identities = 128/483 (26%), Positives = 202/483 (41%), Gaps = 47/483 (9%)

Query: 1594 AVIEGI---PPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEAS 1648
            AV EG+   P  ++ W  N   +E+  +YNIT  E   T  + +K  K+  +  YT  A 
Sbjct: 171  AVFEGVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAG 230

Query: 1649 NTAGTSSVEVTL-KVY------DKPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTK 1700
              +  +S+ V   K++      DK +    P  ++ ++S + +   W     DG    +K
Sbjct: 231  IKSSRASLAVNDDKLHFASGLTDKNALRGKPAELVCKLSTDKINGVW---YKDGNKLTSK 287

Query: 1701 YAIEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALE--SE 1756
              +   +      + V +  D D   Y  +      E M RV   +   F  +AL   S 
Sbjct: 288  DGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDLDALGKFSN 347

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
            P+++K                     S+ I WF   KNG S ++D        G   K  
Sbjct: 348  PVIVKAG------QSASFKMSFPPQPSLEIKWF---KNG-SELLD--------GGSVKVV 389

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                    +I+    + T Q +I  +N  G+    +S   +T+     PP  P    V+E
Sbjct: 390  KESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSS---LTVQDKPGPPQGPVE--VNE 444

Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936
            +TS  + LKW  P+  GGS +TNYIIE   V   +W K+  +  +       ++      
Sbjct: 445  TTSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDIPANHLNFRDRSVSLGKRY 504

Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996
            I+RI AEN  G+S   E++ + +      P PPT P ++     N +  SW  PE DGG 
Sbjct: 505  IYRIYAENPEGISEALETEKI-MAGSLMFPGPPTQP-KVVSAFKNCINLSWTPPEKDGGN 562

Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
             +LGY I  R      W+ +  V   +  LK+ ++D+SE   Y  R+ A N  G  EP  
Sbjct: 563  KILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEYEFRVIAINSSGAGEPST 622

Query: 2055 SDE 2057
              E
Sbjct: 623  PSE 625



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 64/296 (21%), Positives = 129/296 (43%), Gaps = 19/296 (6%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P   D E    ++ G+ + + ++Y+A PQP+ +W+ N + +      K   D  + +L +
Sbjct: 636  PHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSPWN--KIIHDDGTCTLIV 693

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
               + +D+G+Y +  +N+ G A  +  +  +D+P PPG   + ++    + I W    + 
Sbjct: 694  PSSKYSDSGVYTIVAKNSSGQASFD--IEFIDEPRPPGPVELEQLVFGKVIIRWLPSPDH 751

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
                 ++Y+VE Q  ++  W ++ +     T    ++    Y FR YA N++ +SD S++
Sbjct: 752  DRDDRLHYMVEEQNSNSRIWRTIADHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811

Query: 1468 TEY----YKVIKETKI-------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
              +     KV+  + +       + P++  PLK  +        +TC   G+P P + WY
Sbjct: 812  PTWGVNSNKVLAPSTVPTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWY 871

Query: 1517 RDGKKLKTAKATYENRX----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             +G  + +    Y                      YK +A N  G  E S  + ++
Sbjct: 872  HNGICINSDNNYYITNAFGVCSMYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 94/366 (25%), Positives = 157/366 (42%), Gaps = 27/366 (7%)

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--- 1661
            +WYK+GNKL +     I+    T  + ++  K S +  Y  E +     + V V L    
Sbjct: 276  VWYKDGNKLTSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLP 335

Query: 1662 --VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
                D   K   PVI++     S  + + PP     ++  K   E  +  + + +K ++ 
Sbjct: 336  EFDLDALGKFSNPVIVKAGQSASFKMSF-PPQPSLEIKWFKNGSELLDGGSVKVVKESNH 394

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
             R     C++  ++  +   R+  +NP G  EAL S      T  D P            
Sbjct: 395  SRLQIKDCLR--SDTGQIQIRL--KNPFGSIEALSS-----LTVQDKPGPPQGPVEVNET 445

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXX--XXXXXARIQKLSINTTYQ 1836
             +  + + W P +  GGS + +Y +E  Q G+  W+            R + +S+   Y 
Sbjct: 446  TSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDIPANHLNFRDRSVSLGKRYI 505

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTL--TPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            +RIYA N  G S      +KI  G  +   PP+QP+  VVS +    + L WT PE +GG
Sbjct: 506  YRIYAENPEGIS-EALETEKIMAGSLMFPGPPTQPK--VVS-AFKNCINLSWTPPEKDGG 561

Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAENTVGVSLP- 1951
            + I  Y IE +      W  + +V   +   ++ ++++ E  E  FR+ A N+ G   P 
Sbjct: 562  NKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEYEFRVIAINSSGAGEPS 621

Query: 1952 TESQSV 1957
            T S+ V
Sbjct: 622  TPSEMV 627



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
           + +V +  E  + V+A+N  G  E S P  +         P   +P   M+VR G S+ +
Sbjct: 596 VKDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFKDPEDFMVVRSGNSIRI 655

Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGI 813
                  P+P I W KN +PV     K   D  + T++ P  K  D GVYT+ A+NS G 
Sbjct: 656 KINYEAAPQPDIKWLKNGEPVSPW-NKIIHDDGTCTLIVPSSKYSDSGVYTIVAKNSSGQ 714

Query: 814 AETSAVITVEEP 825
           A    +  ++EP
Sbjct: 715 ASFD-IEFIDEP 725



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 84/377 (22%), Positives = 148/377 (39%), Gaps = 25/377 (6%)

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNNEIIS----PSE 877
            +E  +E A+    ++  + I VK  G  +    +  ++P   I  Y+N E++       +
Sbjct: 48   KEKEDEQAKVVENVDNMKPIEVKTSGRAEFEFDMRIKDPNSKIYMYKNGEMLDYGAGSDD 107

Query: 878  TITQNFD--GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
            T   N    G+     I N+    D G Y+    +      +     ++V  V F   L 
Sbjct: 108  TCKHNMKKTGDKYLFSINNLGLN-DGGLYQVDVDDV-----NIITTKLEVPDVEFDGKL- 160

Query: 936  KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXX- 992
            K  +  EG+  + E   S  VS   W  N   +   D   I + E +             
Sbjct: 161  KDVKVVEGQDAVFEGVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKE 220

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            D GV   I   + +   L V +    F   L D        A L  +++++  + VW +D
Sbjct: 221  DNGVYTAIAGIKSSRASLAVNDDKLHFASGLTDKNALRGKPAELVCKLSTDKINGVWYKD 280

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--VELPP--- 1107
            G  +   K+     K G   KL ++N    D G Y   +      A V V  ++LP    
Sbjct: 281  GNKL-TSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDL 339

Query: 1108 EIITRLQNQKVNK-GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            + + +  N  + K G  A+F++      +L ++WFK+GSE+     +++  +    +L+I
Sbjct: 340  DALGKFSNPVIVKAGQSASFKMSFPPQPSLEIKWFKNGSELLDGGSVKVVKESNHSRLQI 399

Query: 1166 YDCDLDDAGEYSCEVGN 1182
             DC   D G+    + N
Sbjct: 400  KDCLRSDTGQIQIRLKN 416



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 79/298 (26%), Positives = 118/298 (39%), Gaps = 31/298 (10%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F        V  G+ I ++    A P+PDI WL  GE + P   I   I  D    C+
Sbjct: 636 PHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSPWNKI---IHDD--GTCT 690

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
           ++ + + K    G YT+VA N  G+AS  I       E  PP  +E L+ ++   G+ +I
Sbjct: 691 LI-VPSSKYSDSGVYTIVAKNSSGQASFDIEF---IDEPRPPGPVE-LEQLVF--GKVII 743

Query: 754 L---SAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKKV-------KDE 800
               S     + R      + N   +   T +D     T++ T+   ++         D 
Sbjct: 744 RWLPSPDHDRDDRLHYMVEEQNSNSRIWRTIADHLLCTTYTTTVQPGQEYHFRIYAKNDM 803

Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRN 859
           G+       + G+     +     PT  N E P  I    ++    KG    +   V   
Sbjct: 804 GLSDPSDSPTWGVNSNKVLAPSTVPTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGL 863

Query: 860 PVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
           P P I WY N   I+      IT  F      + I  V  E DSG+YK VA NS G++
Sbjct: 864 PSPYIAWYHNGICINSDNNYYITNAFG--VCSMYILRVRPE-DSGEYKVVAVNSLGRA 918



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 23/76 (30%), Positives = 37/76 (48%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G +  +T  + G+P P + WY NG  + +D  Y IT       + I  ++   S +Y + 
Sbjct: 851  GYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYITNAFGVCSMYILRVRPEDSGEYKVV 910

Query: 1647 ASNTAGTSSVEVTLKV 1662
            A N+ G +    TLKV
Sbjct: 911  AVNSLGRAECSSTLKV 926



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 3/103 (2%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
           E   ++  +M P F +         G++++ +   E  P+P I W +    + P   +  
Sbjct: 625 EMVCAKNPNMKPHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSP---WNK 681

Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
              DD   TL++      D+G +T VAKN++G AS   E I E
Sbjct: 682 IIHDDGTCTLIVPSSKYSDSGVYTIVAKNSSGQASFDIEFIDE 724



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 1/101 (0%)

Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
           PT       P  +  L+    P G      C V G P P I W+     I    ++ +  
Sbjct: 828 PTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYI-T 886

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           +   V ++ I  V PED+G +  VA N+ G A  ++ L V+
Sbjct: 887 NAFGVCSMYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP+     K     +G    + C +  +P P IAW   G  I  D N  +   ++    C
Sbjct: 836 PPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYI---TNAFGVC 892

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
           S + I  V+    G Y VVAVN  G A     LK+K
Sbjct: 893 S-MYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 6/124 (4%)

Query: 795 KKVKDEGVYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
           K V +   Y  +  A NS G  E S    +      N +P  F +    + V+   +I++
Sbjct: 597 KDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPH-FKDPEDFMVVRSGNSIRI 655

Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
                  P P I W +N E +SP   I  + DG    +V ++  S  DSG Y  VA NS+
Sbjct: 656 KINYEAAPQPDIKWLKNGEPVSPWNKIIHD-DGTCTLIVPSSKYS--DSGVYTIVAKNSS 712

Query: 913 GKSS 916
           G++S
Sbjct: 713 GQAS 716



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 6/96 (6%)

Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTH 787
           ++PP ++ PLK     +G    ++  V G P P I W  N    N       T + G   
Sbjct: 834 EKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYITNAFG-VC 892

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           S+ IL+ +  +D G Y + A NS G AE S+ + V+
Sbjct: 893 SMYILRVRP-EDSGEYKVVAVNSLGRAECSSTLKVK 927


>UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel
            hemicentin protein; n=1; Takifugu rubripes|Rep: Homolog
            of Danio rerio "Novel hemicentin protein - Takifugu
            rubripes
          Length = 2555

 Score =  169 bits (410), Expect = 1e-39
 Identities = 200/885 (22%), Positives = 343/885 (38%), Gaps = 67/885 (7%)

Query: 521  TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP-EDA 578
            TP  GS+V   C+  G P P++TW++    + P   F+M      +  + +R+ F     
Sbjct: 1221 TPQVGSSVTLSCETHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHL 1280

Query: 579  GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
                C   + +       E I  + ++D G   T               +   +PP    
Sbjct: 1281 RLLECCQISDSRLNCQCGEFIFGSQVAD-GGTYTCKVSNVAGQVDRTFRLTVHVPPVLEG 1339

Query: 639  KP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
               ++     GS + L C+    P P I WL  G    P E+   +++    +  S L++
Sbjct: 1340 SLWESLNYTLGSHVSLPCQASGFPVPSITWLKDG---TPIES---SLQWQWSIRGSRLEL 1393

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILS 755
              +     G YT +A N EG+A     L ++      P ++  E    +    GE + L 
Sbjct: 1394 GPLALAHGGLYTCLAKNSEGQAQKDYALTVQVS----PTILDSEHPSEVSAPMGEDMTLE 1449

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDGDT---HSITILKPKKVKDEGVYTLKAENSEG 812
             +  GNP P ++W K+   V+   ++  G T    ++T+L+     D G YT  A +  G
Sbjct: 1450 CRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTPEGSTLTLLR-LSPDDSGTYTCLAVSPAG 1508

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
                   + V  P   + E  +     +E+ V + G + L  +   +P P I+W +N   
Sbjct: 1509 RQTKIYTLFVLVPPSISGETTV----PREVQVTQDGAVTLECQAVGSPPPQISWLKNGHP 1564

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +  S   T+    +++ L I+ V    DSG Y C+A + AG +     V + VE VT V 
Sbjct: 1565 LLLSSR-TRLLSADSV-LRISPVQLS-DSGVYTCMARSQAGLAELSYDVQVQVEPVTIV- 1620

Query: 933  HLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
                     +G  V L C+       +  W  + + +S   HR ++ +G+          
Sbjct: 1621 ---------QGSLVTLSCEARGVPPPTLTWLKDGQPLS--LHRNLLLDGQETRLQLPDVG 1669

Query: 991  XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI---LEVEINS---ET 1044
              D G+  C+  +Q  S+      T+ E  +       +E  +A+   LE+E ++     
Sbjct: 1670 PSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVT 1101
              + W +DG    P + +   ++ GH   + I    V D G Y+C+   L  E       
Sbjct: 1730 PTLTWLKDGH---PLERRDIVQEDGHF--VRISKVQVEDAGLYTCLASSLAGEDGKNHWI 1784

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158
             V++PP ++   + + V         +E L   D    + W+KD  ++Q    +Q    G
Sbjct: 1785 RVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGG 1844

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
              Q L+I +   +D+G YSC V N     +   TVE             +      DA L
Sbjct: 1845 --QYLEIQEVKPEDSGLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVTTHIGQDALL 1902

Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
              E+ +E+   VTW K    I    ++TL+S+    +L I      D   Y C + +   
Sbjct: 1903 PCEVEEESHATVTWRKDGFPITQDNRYTLLSE---GSLRIHGVQLSDAGRYYCTVSNQAG 1959

Query: 1276 TTKLKVEVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            +    VE+  F  P I        +  G    L  +    P P   W  N   +   + +
Sbjct: 1960 SDHRGVELRVFVGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLS 2019

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
                   S SL +    N D G ++    N  G     + V + D
Sbjct: 2020 GAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAGEERRVIEVILQD 2064



 Score =  153 bits (371), Expect = 5e-35
 Identities = 208/911 (22%), Positives = 349/911 (38%), Gaps = 85/911 (9%)

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
            +V D G YT K  N  G  + +  +TV  P      P L  + ++ +       + L  +
Sbjct: 1305 QVADGGTYTCKVSNVAGQVDRTFRLTVHVP------PVLEGSLWESLNYTLGSHVSLPCQ 1358

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
             +  PVPSITW ++   I  S     +  G  +EL    +      G Y C+A NS G++
Sbjct: 1359 ASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLAL---AHGGLYTCLAKNSEGQA 1415

Query: 916  SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHR 973
                 +T+ V                 G+ + LEC+ +   T    W  +   + G D R
Sbjct: 1416 QKDYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSR 1475

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLV-VKETIPEFIRKLQDFE 1027
             I                 D G   C+      +  +  T+ V V  +I       ++ +
Sbjct: 1476 HIGVTPEGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQ 1535

Query: 1028 VKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
            V +     LE + + S    + W ++G  +              +R   I    + D G 
Sbjct: 1536 VTQDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTRLLSADSVLR---ISPVQLSDSGV 1592

Query: 1087 YSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145
            Y+C+ R ++  AE++  V++  E +T +Q   V    +A      T     + W KDG  
Sbjct: 1593 YTCMARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGVPPPT-----LTWLKDGQP 1647

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201
            +  S H  L +DG++ +L++ D    DAG YSC    + G+S  T  LTV EP       
Sbjct: 1648 L--SLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSS 1705

Query: 1202 LPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
             PE + +  N+   L      +P  TL  TW K    +E  +    I       + I K 
Sbjct: 1706 SPEELFIAVNSPLELECSATGVPPPTL--TWLKDGHPLERRD----IVQEDGHFVRISKV 1759

Query: 1259 TEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFP 1315
              +D   YTC+    A    K     V+ PP ++  D  R   +     +TL     + P
Sbjct: 1760 QVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDP 1819

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P+ EW  +   ++     +     +   L I++V+  D+G+Y   + N  G + +   V
Sbjct: 1820 APDIEWYKDEVKVQLGGRVQQLAGGQY--LEIQEVKPEDSGLYSCVVTNMAGSSSLFFTV 1877

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
             IL        P I+   SS +        + G   ++   VE +   T  W        
Sbjct: 1878 EIL-------LPPIIRESSSEVTT------HIGQDALLPCEVEEESHATVTWRK-DGFPI 1923

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
            TQ +   L +  S R     +++      + +++    ++ ++      P++     N+T
Sbjct: 1924 TQDNRYTLLSEGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVGPSISPGPFNVT 1983

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXXXY 1548
                    L+C   G+P PKV+W R+G  L  ++ +   R                   +
Sbjct: 1984 VTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEGYF 2043

Query: 1549 KCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKVGDEWLVTAV----------I 1596
            +C A N+ GE      V +Q  Q  V       +    +  D   VTAV          +
Sbjct: 2044 ECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIE-DDVTAVTAVKLAPAVLPCHV 2102

Query: 1597 EGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             G P P V W K G KL +    Y +     T ++ I  +  SH+ +YT  A N+AG + 
Sbjct: 2103 HGRPQPTVFWTKGGAKLSSRGGTYRVL---PTGLLEITSVLPSHAGRYTCSARNSAGVAH 2159

Query: 1656 VEVTLKVYDKP 1666
              V+L V + P
Sbjct: 2160 KHVSLSVQESP 2170



 Score =  151 bits (365), Expect = 3e-34
 Identities = 247/1186 (20%), Positives = 439/1186 (37%), Gaps = 96/1186 (8%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G T    C V+ YP P+ITW R   I+       +         L +     EDAG + 
Sbjct: 1129 EGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPGGQ---MLQLPRARLEDAGQYV 1185

Query: 583  CVAKNAAGFASSTTELIVEA-----PLSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTF 636
            C A N+AG    +  L V       P  D  S++                   G+P P  
Sbjct: 1186 CTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCET---HGVPEPEV 1242

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            +       +   +   ++   + I    +   F    +   E   ++ +S ++  C    
Sbjct: 1243 TWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHLRLLECCQIS-DSRLNCQCGEF- 1300

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILS 755
            I   +    GTYT    N  G+      L +      PP +   L +S+    G  V L 
Sbjct: 1301 IFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHV----PPVLEGSLWESLNYTLGSHVSLP 1356

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
             Q  G P P+ITW K+  P+++          S   L P  +   G+YT  A+NSEG A+
Sbjct: 1357 CQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLALAHGGLYTCLAKNSEGQAQ 1416

Query: 816  TSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
                +TV+  PT  ++E P       E++      + L  R   NP P ++W ++   + 
Sbjct: 1417 KDYALTVQVSPTILDSEHP------SEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVE 1470

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKH 933
             S++       E   L +  +  + DSG Y C+A + AG+ +    + + V   ++    
Sbjct: 1471 GSDSRHIGVTPEGSTLTLLRLSPD-DSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETT 1529

Query: 934  LQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            + +  +  +   V LECQ   S      W  N   +       ++               
Sbjct: 1530 VPREVQVTQDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTRLLSAD--SVLRISPVQL 1587

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWE 1050
             D GV  C+ + Q     L     +     +++   + +  +  L  E        + W 
Sbjct: 1588 SDSGVYTCMARSQAGLAELSYDVQV-----QVEPVTIVQGSLVTLSCEARGVPPPTLTWL 1642

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELP 1106
            +DG+ +   +N       G   +L + +    D G YSC+  +++     T  +TV+E P
Sbjct: 1643 KDGQPLSLHRNLL---LDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLE-P 1698

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            P++      +++     +  E+E +        + W KDG  ++  + +Q   DG    +
Sbjct: 1699 PKMTGSSSPEELFIAVNSPLELECSATGVPPPTLTWLKDGHPLERRDIVQE--DG--HFV 1754

Query: 1164 KIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            +I    ++DAG Y+C      G       + V+ P           + VP N   +LT+E
Sbjct: 1755 RISKVQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVN--GHLTLE 1812

Query: 1220 I---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
                 D   D+ WYK +  ++   +   ++    + L I++   +D   Y+CV+ +   +
Sbjct: 1813 CLADSDPAPDIEWYKDEVKVQLGGRVQQLAG--GQYLEIQEVKPEDSGLYSCVVTNMAGS 1870

Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT 1334
            + L   V +  PP I +   E     G D  L  + +        W  +   I +  ++T
Sbjct: 1871 SSLFFTVEILLPPIIRESSSEVTTHIGQDALLPCEVEEESHATVTWRKDGFPITQDNRYT 1930

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEI 1392
              S      SL I  V+ +DAG Y   + N  G  H  VE+ V +    SP G  N+   
Sbjct: 1931 LLS----EGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVGPSISP-GPFNVTVT 1985

Query: 1393 DS-SSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
                ++  C    E TG  S  + +      +D ++      +  + + +    +N    
Sbjct: 1986 SGIRAVLSC----ETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEG 2041

Query: 1451 -FRAYAVNEVDISDASETTEYYKVIKETKI-------QSPTVEKPLKNITTEPNEDIELT 1502
             F   AVNE    +     E      +T +         P++E  +  +T        L 
Sbjct: 2042 YFECTAVNEA--GEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLP 2099

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            C   G PQP V W + G KL +   TY                    Y C A N  G   
Sbjct: 2100 CHVHGRPQPTVFWTKGGAKLSSRGGTYRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAH 2159

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
                + +Q+ P I    E+++     G   ++    +G P P + W + G  +      +
Sbjct: 2160 KHVSLSVQESPEIRPMAEEVQVVLHHGT--VLPCEAQGFPRPSISWQREGVPIATGHRLS 2217

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            + +      ++   +    +  Y   A N AG +  +  L ++  P
Sbjct: 2218 LLS---NGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPP 2260



 Score =  136 bits (330), Expect = 5e-30
 Identities = 171/743 (23%), Positives = 297/743 (39%), Gaps = 86/743 (11%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C   G P P ITW +      P     +Y  + N   L I  V PE AG F+C A+N+AG
Sbjct: 548  CDAFGIPSPTITWSKDG---HPVDTPGVYLQNGN-RMLRIYRVQPEHAGRFSCTAQNSAG 603

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
             A     ++V+     H  +  +                     T S       V  G +
Sbjct: 604  EARREYSIVVQGK---HIKQPPLTTRTL----------------TMSVSNAELTVALGQE 644

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            +  +C++   P P + W   GE +  D +  V    D      VLK+  V+   +G Y  
Sbjct: 645  VEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQ----VLKVKAVRLRDQGIYQC 700

Query: 711  VAVNREGEASLPIVLKIKTGE-----KEPPQVIEPLKS--MIVRQGESVILSAQVVGNPR 763
            +A N  G       L ++          PP +  P ++  + V  G S +LS  V G+P 
Sbjct: 701  LASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPT 760

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            P+ITW K+N+P+ + P  +         L   +    G+YT +A N  G A     + V 
Sbjct: 761  PSITWLKDNQPIVSSPQLTYTRGGQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVL 820

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
             P +   + P+F     E  V+  G++ L       P P I W+++ ++++ S  +    
Sbjct: 821  VPPQIEGDSPVF--GTHEEKVRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGS--VHTGI 876

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF-VKHLQKSY---- 938
                  L+I N    +  G Y CV +NSAG+      VTI V  V   V + + ++    
Sbjct: 877  QELGHSLLIENT-MLVHEGQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGH 935

Query: 939  ------ETEE------GKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXX 984
                  +T E      G  V L C+++     K  W+ + +++   D   ++  G+    
Sbjct: 936  EGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQ--VL 993

Query: 985  XXXXXXXXDVGVIKC-IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                    D G   C  V +     M      + +F   +++         +L  ++  +
Sbjct: 994  QIARVRKDDAGRYTCQAVNEAGEDHMHFELHILEQF---MEEIAAVVNSTVVLHCDVTGQ 1050

Query: 1044 -TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--- 1099
             T  V W RDG+ ++    ++   K G   +L + +  V D   Y C+  ++  T E   
Sbjct: 1051 PTPAVSWLRDGQPVQ-LDPQHQISKDG--TQLQLLSVQVSDMAGYLCVAENKVGTVEKLF 1107

Query: 1100 VTVVELPPEIITRLQNQ-KVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157
               +++PP I   ++ +  V +G+ A+   ++       + W +DG  + F   + +   
Sbjct: 1108 SLTIQVPPRISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPG 1167

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP-AN 1211
            G  Q L++    L+DAG+Y C   NS     K   +     P++   L     ++ P   
Sbjct: 1168 G--QMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVG 1225

Query: 1212 TDAYLTVE---IPDETLDVTWYK 1231
            +   L+ E   +P+   +VTWYK
Sbjct: 1226 SSVTLSCETHGVPEP--EVTWYK 1246



 Score =  125 bits (302), Expect = 1e-26
 Identities = 247/1225 (20%), Positives = 450/1225 (36%), Gaps = 156/1225 (12%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  V+F+CQV G P P++ W R   ++    D  + + +D    L ++ V   D G + C
Sbjct: 642  GQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDG-QVLKVKAVRLRDQGIYQC 700

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            +A N AG       L V+          T+                   PPT     +  
Sbjct: 701  LASNNAGTQMRQFRLTVQV--------RTIVVVCLS-------------PPTIKGPSETS 739

Query: 644  YVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
             V    G   LL C +   P P I WL   + IV    ++             L++ +V+
Sbjct: 740  EVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGG------QALRLGSVQ 793

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVG 760
                G YT  A N  G A     L +    + E    +       VR   S+ LS    G
Sbjct: 794  GDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKG 853

Query: 761  NPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
             P P I W K+ + +  ++ T      HS+ +++   +  EG YT    NS G  +    
Sbjct: 854  FPEPKIQWFKDGQLLTGSVHTGIQELGHSL-LIENTMLVHEGQYTCVVTNSAGEDKRDFH 912

Query: 820  ITVEEP------TEENAEPPLFINRFQEITVKEKGTIKLVARVTRN------PVPSITWY 867
            +T++ P      T   A   L      E    EK  + L   V+ +      P P ++W+
Sbjct: 913  VTIQVPPVFHRVTNREAAWGLGHEGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWH 972

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++ + +   + +     G+ +++     D   D+G Y C A N AG+      + I    
Sbjct: 973  KDGQKLLSGDGVVLLPGGQVLQIARVRKD---DAGRYTCQAVNEAGEDHMHFELHI---- 1025

Query: 928  VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
               ++   +        TV+L C  +   T +  W  + + +      +I ++G      
Sbjct: 1026 ---LEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDG--TQLQ 1080

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKL-QDFEVKEKDVAILEVEIN 1041
                   D+    C+ +++  +   +   TI   P     + ++  V E   A L  ++ 
Sbjct: 1081 LLSVQVSDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIEGHTASLLCDVQ 1140

Query: 1042 S-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
            +    ++ W RDG+I+      +        + L +    + D G+Y C   + +   + 
Sbjct: 1141 AYPPPEITWTRDGQILAFGTGVHILPGG---QMLQLPRARLEDAGQYVCTATNSAGQDQK 1197

Query: 1101 TV---VELPPEIITRLQNQK----VNKGNKATFEIELTKG--DALVRWFKDGSEIQFSN- 1150
            ++   V + P +  RL           G+  T   E T G  +  V W+K+G ++   N 
Sbjct: 1198 SILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCE-THGVPEPEVTWYKNGLQLAPRNG 1256

Query: 1151 ----HIQLTIDGKKQK-------LKIYDC-------------------DLDDAGEYSCEV 1180
                  QL I G + +       L++ +C                    + D G Y+C+V
Sbjct: 1257 FEMDRYQLEIVGVQVRKTFDVTHLRLLECCQISDSRLNCQCGEFIFGSQVADGGTYTCKV 1316

Query: 1181 ----GNSKCTAILTVEEP---------SINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227
                G    T  LTV  P         S+N+T  L   + +P     +    +P     +
Sbjct: 1317 SNVAGQVDRTFRLTVHVPPVLEGSLWESLNYT--LGSHVSLPCQASGF---PVP----SI 1367

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEF 1286
            TW K  + IE + ++     ++   L +          YTC+  +++   +    + V+ 
Sbjct: 1368 TWLKDGTPIESSLQWQW--SIRGSRLELGPLALAHGGLYTCLAKNSEGQAQKDYALTVQV 1425

Query: 1287 PPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             P I+D E   E     G D+TL       P P+  W+ +   ++        +  + ++
Sbjct: 1426 SPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTPEGST 1485

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            LT+ ++   D+G Y     +  G       + +L  PS  G+  +       + +  D  
Sbjct: 1486 LTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTV----PREVQVTQD-- 1539

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
               G  T+    V         W+   +     +  + L  +S  R     ++ V +SD+
Sbjct: 1540 ---GAVTLECQAVG-SPPPQISWLKNGHPLLLSSRTRLLSADSVLR-----ISPVQLSDS 1590

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
               T   +        S  V+  ++ +T      + L+C   GVP P +TW +DG+ L  
Sbjct: 1591 GVYTCMARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGVPPPTLTWLKDGQPLSL 1650

Query: 1525 AKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
             +                       Y C+A N  G    +  + + + P +T S+   + 
Sbjct: 1651 HRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEEL 1710

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
               V     +     G+PPP + W K+G+ LE         +E    +RI +++   +  
Sbjct: 1711 FIAVNSPLELECSATGVPPPTLTWLKDGHPLER----RDIVQEDGHFVRISKVQVEDAGL 1766

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS 1667
            YT  AS+ AG       ++V   P+
Sbjct: 1767 YTCLASSLAGEDGKNHWIRVQVPPT 1791



 Score =  121 bits (291), Expect = 3e-25
 Identities = 171/778 (21%), Positives = 302/778 (38%), Gaps = 86/778 (11%)

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P P I W   G EI P+++   ++  D       L I        G +T VA N  G   
Sbjct: 461  PRPKIRWFRNGLEIHPEQS-DFSVGED-----GALVIRAASASHSGDFTCVATNEAGSVE 514

Query: 721  LPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
                LK+      PP++    +PL ++ V   + + L     G P PTITW K+  PV  
Sbjct: 515  RKTRLKVNV----PPEIQDDTQPL-NLTVTLKQPLTLGCDAFGIPSPTITWSKDGHPVDT 569

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
                       + I + +  +  G ++  A+NS G A     I V+   +   +PPL   
Sbjct: 570  PGVYLQNGNRMLRIYRVQP-EHAGRFSCTAQNSAGEARREYSIVVQG--KHIKQPPLTTR 626

Query: 838  RFQ------EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
                     E+TV     ++   +V   P P + W R+ E++S        F  +   L 
Sbjct: 627  TLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLK 686

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV----KHLQKSYETEE----- 942
            +  V    D G Y+C+ASN+AG      R+T+ V  +  V      ++   ET E     
Sbjct: 687  VKAVRLR-DQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVL 745

Query: 943  GKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            G + +L C  + S T S  W  + + I         + G+              G+  C 
Sbjct: 746  GFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGGQ--ALRLGSVQGDSTGLYTCR 803

Query: 1001 VKD------QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWER 1051
              +      +  S +++V   I          E K +    L +   ++      + W +
Sbjct: 804  ATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQWFK 863

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPE 1108
            DG+++    +    ++ GH   L I NT +  EG+Y+C++ +   E        +++PP 
Sbjct: 864  DGQLLTGSVHT-GIQELGH--SLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQVPP- 919

Query: 1109 IITRLQNQKVNKG--------NKATFEIELTKGDAL-------------VRWFKDGSEIQ 1147
            +  R+ N++   G        +    ++++  G  +             + W KDG ++ 
Sbjct: 920  VFHRVTNREAAWGLGHEGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLL 979

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
              + + L   G  Q L+I     DDAG Y+C+  N      +  E   ++   +  E I 
Sbjct: 980  SGDGVVLLPGG--QVLQIARVRKDDAGRYTCQAVNEAGEDHMHFE---LHILEQFMEEIA 1034

Query: 1208 VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
               N+   L  ++  + T  V+W +    ++   +  +  D  +  L+       D   Y
Sbjct: 1035 AVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLL--SVQVSDMAGY 1092

Query: 1267 TCVLLDAKSTT-KLKVEVVEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
             CV  +   T  KL    ++ PP+I  + E E  +  G   +LL D QA+P P   W  +
Sbjct: 1093 LCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRD 1152

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             +I+     T   I      L + +    DAG Y     N+ G     + +++  +P+
Sbjct: 1153 GQIL--AFGTGVHILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPT 1208



 Score =  117 bits (281), Expect = 4e-24
 Identities = 183/803 (22%), Positives = 292/803 (36%), Gaps = 98/803 (12%)

Query: 630  EGIPPTFSKKPK------AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
            + +  TFS+ P+      A +V  G+D +LEC+    P P + W FKGE  V     +  
Sbjct: 164  QSVSLTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRW-FKGEFEVGSTPFA-- 220

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLK 742
               D+H     L I  V++   G YT VA +  G A+  ++LK+    K       +   
Sbjct: 221  -GQDVHH--GDLHIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTV 277

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802
             M V  G  V+L  +  GNP P +TW +N  P+  +             +   ++ D   
Sbjct: 278  KMAVEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTVLPSGSLRITDVRLIDSKR 337

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            YT  AEN  G    S  + ++          L   R  +       T+ L   V   P P
Sbjct: 338  YTCTAENPAGNVSLSYNLHIQAKPRIQPAATLLKARIGQ-------TVTLPCVVQGEPSP 390

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             +TW+ N   +              +           D G Y+CVA+NSAG+ +   ++ 
Sbjct: 391  EVTWFHNGLPVGIKNATPLRIHQAKLG----------DQGTYRCVATNSAGQETSEIKLD 440

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
            I V + +   H           + +     S     +W+ N  EI     +     G   
Sbjct: 441  ILVRRNSAFAH-----------SFVFVNSGSPRPKIRWFRNGLEIH--PEQSDFSVGEDG 487

Query: 983  XXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQ--DFEVKEKDVAIL 1036
                        G   C+  ++    E  T L V    PE     Q  +  V  K    L
Sbjct: 488  ALVIRAASASHSGDFTCVATNEAGSVERKTRLKV-NVPPEIQDDTQPLNLTVTLKQPLTL 546

Query: 1037 EVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
              +     +  + W +DG    P      + + G+ R L I        G +SC  ++ +
Sbjct: 547  GCDAFGIPSPTITWSKDGH---PVDTPGVYLQNGN-RMLRIYRVQPEHAGRFSCTAQNSA 602

Query: 1096 CTA--EVTVVE-----LPPEIITRLQNQKVNK-------GNKATFEIELT-KGDALVRWF 1140
              A  E ++V        P + TR     V+        G +  F+ ++  K    V W 
Sbjct: 603  GEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWS 662

Query: 1141 KDGSEIQFSN--HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEP 1194
            +DG  +      H++   DG  Q LK+    L D G Y C   N+  T +    LTV+  
Sbjct: 663  RDGEVLSRDGDPHVEFHEDG--QVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVR 720

Query: 1195 SINFTLRLPEFILVPANT---------DAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244
            +I      P  I  P+ T            L+ ++    T  +TW K    I  + + T 
Sbjct: 721  TIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTY 780

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKI-----VDYEREYR 1298
                  + L +     D    YTC   +   T  K    VV  PP+I     V    E +
Sbjct: 781  TRG--GQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEK 838

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++    +TL    + FP+P  +W  + +++    HT   I     SL I+       G Y
Sbjct: 839  VRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHT--GIQELGHSLLIENTMLVHEGQY 896

Query: 1359 KLRLENNCGHADVEMNVTILDKP 1381
               + N+ G    + +VTI   P
Sbjct: 897  TCVVTNSAGEDKRDFHVTIQVPP 919



 Score =  112 bits (270), Expect = 9e-23
 Identities = 134/624 (21%), Positives = 251/624 (40%), Gaps = 43/624 (6%)

Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRL-QNQKVNKGNKATFEIEL 1130
            +I  + V D G Y+C + + +   + T    V +PP +   L ++     G+  +   + 
Sbjct: 1300 FIFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLNYTLGSHVSLPCQA 1359

Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA-- 1187
            +      + W KDG+ I+ S   Q +I G +  L++    L   G Y+C   NS+  A  
Sbjct: 1360 SGFPVPSITWLKDGTPIESSLQWQWSIRGSR--LELGPLALAHGGLYTCLAKNSEGQAQK 1417

Query: 1188 --ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244
               LTV+          P  +  P   D  L      + T  ++W K    +E ++   +
Sbjct: 1418 DYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHI 1477

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI---VDYEREYRIK 1300
                +  TL + + + DD   YTC+ +  A   TK+    V  PP I       RE ++ 
Sbjct: 1478 GVTPEGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQVT 1537

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
            +   VTL       P P   W+ N   +     T+  + S  + L I  V+ +D+G+Y  
Sbjct: 1538 QDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTR--LLSADSVLRISPVQLSDSGVYTC 1595

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
               +  G A++  +V +  +P    + +++ +   +  +    P  T     + ++ + Q
Sbjct: 1596 MARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGV----PPPT-----LTWLKDGQ 1646

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
             +     + +    +T+  + ++  + +  +   A N+   S  +      +  K T   
Sbjct: 1647 PLSLHRNLLLDG-QETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSS 1705

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540
            SP      + +    N  +EL C   GVP P +TW +DG  L+      E+         
Sbjct: 1706 SP------EELFIAVNSPLELECSATGVPPPTLTWLKDGHPLERRDIVQEDGHFVRISKV 1759

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y C+A +  GE   +  + +Q  P +  S+E       V     +  + +  P
Sbjct: 1760 QVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDP 1819

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
             P++ WYK+  K++      +        + I+E+K   S  Y+   +N AG+SS+  T+
Sbjct: 1820 APDIEWYKDEVKVQLGG--RVQQLAGGQYLEIQEVKPEDSGLYSCVVTNMAGSSSLFFTV 1877

Query: 1661 KVYDKPSKPEGPVIMREISRESVT 1684
            ++   P       I+RE S E  T
Sbjct: 1878 EILLPP-------IIRESSSEVTT 1894



 Score =  110 bits (264), Expect = 5e-22
 Identities = 188/959 (19%), Positives = 346/959 (36%), Gaps = 93/959 (9%)

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            G   +LS +V G+ R  +TW +  + + A   +S     S   +   +++D G Y   A 
Sbjct: 7    GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSLQISGVQIQDAGEYHCVAT 66

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N+ G  ++  ++ +  P     E P  +   Q         I+ V   + +P P + W  
Sbjct: 67   NAHG--DSRIIVWLHVP-----EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSH 119

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             N +++  + +  N  G    L I     E D+G+Y C+A+N AG +S    V++   + 
Sbjct: 120  GNMLLTNRQRLNINHYG---VLTIKGALPE-DAGNYTCLATNEAGVASQS--VSLTFSEA 173

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXX 986
              ++  Q++     G   +LECQ +       +W+  + E+         Q+        
Sbjct: 174  PRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAG--QDVHHGDLHI 231

Query: 987  XXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI-----RKLQDFEVKEKDVAILEV 1038
                  D G   C+        T T+++    +P+ I      K     V+     +L  
Sbjct: 232  RGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPC 291

Query: 1039 EINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            E     + +V W R+G  I P    +     G +R   I +  + D   Y+C   + +  
Sbjct: 292  EAQGNPSPLVTWSRNGHPIPPVTAGFTVLPSGSLR---ITDVRLIDSKRYTCTAENPAGN 348

Query: 1098 AEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152
              ++    ++  P I       K   G   T    + +G+    V WF +G  +   N  
Sbjct: 349  VSLSYNLHIQAKPRIQPAATLLKARIGQTVTLPC-VVQGEPSPEVTWFHNGLPVGIKN-- 405

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
                      L+I+   L D G Y C   NS   A     E  ++  +R        A  
Sbjct: 406  -------ATPLRIHQAKLGDQGTYRCVATNS---AGQETSEIKLDILVRRNS-----AFA 450

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             +++ V        + W++    I   +    + +     L+IR  +     ++TCV  +
Sbjct: 451  HSFVFVNSGSPRPKIRWFRNGLEIHPEQSDFSVGE--DGALVIRAASASHSGDFTCVATN 508

Query: 1273 AKSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
               + + K  + V  PP+I D  +     +     +TL  D    P P   W   SK   
Sbjct: 509  EAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGCDAFGIPSPTITW---SKDGH 565

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--PSPPGKP 1387
                    + + +  L I +V+   AG +    +N+ G A  E ++ +  K    PP   
Sbjct: 566  PVDTPGVYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTT 625

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--------TKTQTS 1439
              L +  S+  +        G        V  +     EW     +         +    
Sbjct: 626  RTLTMSVSNAEL----TVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHED 681

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASET-------TEYYKVIKETKIQSPTVEKP--LKN 1490
             Q LK   + R R   + +   S+ + T       T   + I    +  PT++ P     
Sbjct: 682  GQVLKV-KAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSE 740

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY-ENRXXXXXXXXXXXXXXXY 1548
            ++        L+C   G P P +TW +D + +  + + TY                   Y
Sbjct: 741  VSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGGQALRLGSVQGDSTGLY 800

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPEVI 1605
             C A N  G       + +   P I   +      ++K ++     ++ + +G P P++ 
Sbjct: 801  TCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQ 860

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKV 1662
            W+K+G  L       I  +E    + I+     H  +YT   +N+AG       VT++V
Sbjct: 861  WFKDGQLLTGSVHTGI--QELGHSLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQV 917



 Score =  106 bits (254), Expect = 8e-21
 Identities = 135/567 (23%), Positives = 219/567 (38%), Gaps = 66/567 (11%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P+    P+++    G +I   C     P P + W      +   + +++        +  
Sbjct: 84   PSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNIN-------HYG 136

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            VL I        G YT +A N  G AS  + L       E P++    +++ V  G   +
Sbjct: 137  VLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFS----EAPRIRVTQQAIHVSVGADAV 192

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L  Q  G P P + W K    V + P       H    ++  +  D G YT  A +  G 
Sbjct: 193  LECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHGDLHIRGVQEVDAGRYTCVASSPAGT 252

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVK---EKGT-IKLVARVTRNPVPSITWYRN 869
            A  + ++ V       A P +      + TVK   E GT + L      NP P +TW RN
Sbjct: 253  ATGTVILKV------GAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPSPLVTWSRN 306

Query: 870  NEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
               I P   +T  F    +  L IT+V   IDS  Y C A N AG  S      + ++  
Sbjct: 307  GHPIPP---VTAGFTVLPSGSLRITDV-RLIDSKRYTCTAENPAGNVS--LSYNLHIQAK 360

Query: 929  TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
              ++      +   G+TV L C  Q   +    W+HN   + G+ +   ++         
Sbjct: 361  PRIQPAATLLKARIGQTVTLPCVVQGEPSPEVTWFHNGLPV-GIKNATPLR--------I 411

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                  D G  +C+  +        +K  I   +R+   F       + + V   S    
Sbjct: 412  HQAKLGDQGTYRCVATNSAGQETSEIKLDI--LVRRNSAFA-----HSFVFVNSGSPRPK 464

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103
            + W R+G  I P+++ +   + G    L IR  S    G+++C+  +E+ + E      V
Sbjct: 465  IRWFRNGLEIHPEQSDFSVGEDG---ALVIRAASASHSGDFTCVATNEAGSVERKTRLKV 521

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKG-DAL------VRWFKDGSEIQFSNHIQLTI 1156
             +PPEI  +   Q +N     T +  LT G DA       + W KDG  +       + +
Sbjct: 522  NVPPEI--QDDTQPLNL--TVTLKQPLTLGCDAFGIPSPTITWSKDGHPVDTPG---VYL 574

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
                + L+IY    + AG +SC   NS
Sbjct: 575  QNGNRMLRIYRVQPEHAGRFSCTAQNS 601



 Score =  101 bits (241), Expect = 3e-19
 Identities = 101/389 (25%), Positives = 154/389 (39%), Gaps = 41/389 (10%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C+ +G+PRP I+W R+   I       +  +      L    V   DAGT+ C+AKN AG
Sbjct: 2191 CEAQGFPRPSISWQREGVPIATGHRLSLLSN----GALKFSRVTLGDAGTYQCLAKNEAG 2246

Query: 591  FASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
             A   T+L++  P  +S   +E++V                +G P      PK  +   G
Sbjct: 2247 AAVGQTKLVLHVPPLISPAQTELSVIQGFQALLSCAA----QGSPD-----PKISWEKNG 2297

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN----VKKFQ 704
            S +        IP      L  GE I+    + + I + + +      +       +   
Sbjct: 2298 SPV------PNIPGKYTV-LRSGELIIERAEVCLLILAALRLEAHQNPLNQFWFLTQPAD 2350

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G +T VA N  G A     L I       P   E    + + +G+S+ LS    G P P
Sbjct: 2351 AGLFTCVATNAAGSARQDRRLSINMR----PAFKELPGDVTLNKGQSLALSCHAQGTPSP 2406

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             I+W  NN P +       G   S  I++     D G Y   AEN  G   T + + V E
Sbjct: 2407 VISWTVNNSPRQGAAVDEAG--RSSLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVRE 2464

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P      P L  +     TV +  +  L   +  +P P + W R+   +  S  I    +
Sbjct: 2465 P------PVLKGDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLN 2518

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAG 913
            G    LVI +V+     G+Y+C+A N AG
Sbjct: 2519 G---SLVIYSVNVNTHEGEYQCLAENEAG 2544



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 137/603 (22%), Positives = 239/603 (39%), Gaps = 63/603 (10%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G      C+  G P P+++W R    +  SQ     +   +  +LV+     ED G F C
Sbjct: 1987 GIRAVLSCETTGIPSPKVSWKRNGTPLDVSQ-LSGAFRLLSSGSLVLLSPSNEDEGYFEC 2045

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
             A N AG        ++E  L D  +++ V              +   +PP+      A 
Sbjct: 2046 TAVNEAG----EERRVIEVILQDGQTDVCVF-------------MFCSVPPSIEDDVTAV 2088

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
               + +  +L C +   P+P + W   G ++         + + +      L+IT+V   
Sbjct: 2089 TAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYRVLPTGL------LEITSVLPS 2142

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
              G YT  A N  G A   + L ++    E P++    + + V      +L  +  G PR
Sbjct: 2143 HAGRYTCSARNSAGVAHKHVSLSVQ----ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPR 2198

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA--ETSAVIT 821
            P+I+W +   P+      S     ++   +   + D G Y   A+N  G A  +T  V+ 
Sbjct: 2199 PSISWQREGVPIATGHRLSLLSNGALKFSRVT-LGDAGTYQCLAKNEAGAAVGQTKLVLH 2257

Query: 822  VEEPTEENAEPPL-FINRFQEI-TVKEKGTI--KLVARVTRNPVPSI----TWYRNNE-I 872
            V  P    A+  L  I  FQ + +   +G+   K+      +PVP+I    T  R+ E I
Sbjct: 2258 VP-PLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELI 2316

Query: 873  ISPSETITQNFDGENIELVITNVDS------EIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            I  +E          +E     ++         D+G + CVA+N+AG +    R++I++ 
Sbjct: 2317 IERAEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSINMR 2376

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXX 984
                 K L       +G+++ L C    T S    W  N     G      + E      
Sbjct: 2377 PA--FKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPRQG----AAVDEAGRSSL 2430

Query: 985  XXXXXXXXDVGVIKCIVKDQETS--TMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEI 1040
                    D G   C+ +++  S  T+  V+   P  ++        V +    IL+  I
Sbjct: 2431 IIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCPI 2490

Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            + + + V+ W RDG  +  + ++      G +  +Y  N + H EGEY C+  +E+ TAE
Sbjct: 2491 HGDPSPVLQWLRDGNALL-RSHRIQALLNGSL-VIYSVNVNTH-EGEYQCLAENEAGTAE 2547

Query: 1100 VTV 1102
             T+
Sbjct: 2548 RTI 2550



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 168/792 (21%), Positives = 294/792 (37%), Gaps = 98/792 (12%)

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK--KPKAQYVDEGSDILLEC 655
            L++ A  + H  + T               +   +PP      +P    V     + L C
Sbjct: 489  LVIRAASASHSGDFTCVATNEAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGC 548

Query: 656  RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
                IP P I W   G    P +   V +++   M    L+I  V+    G ++  A N 
Sbjct: 549  DAFGIPSPTITWSKDGH---PVDTPGVYLQNGNRM----LRIYRVQPEHAGRFSCTAQNS 601

Query: 716  EGEASLPIVLKIKTGE-KEPPQVIEPL------KSMIVRQGESVILSAQVVGNPRPTITW 768
             GEA     + ++    K+PP     L        + V  G+ V    QV G P P + W
Sbjct: 602  AGEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEW 661

Query: 769  CKNNKPVKALPTKSDGDTH-------SITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             ++ + +       DGD H        +  +K  +++D+G+Y   A N+ G       +T
Sbjct: 662  SRDGEVL-----SRDGDPHVEFHEDGQVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLT 716

Query: 822  VEEPT--EENAEPPLF--INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
            V+  T       PP     +   E++V    +  L   V  +P PSITW ++N+ I  S 
Sbjct: 717  VQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSP 776

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVT-----IDVEKVTFV 931
             +T    G+ + L     DS   +G Y C A+N AG +  H + V      I+ +   F 
Sbjct: 777  QLTYTRGGQALRLGSVQGDS---TGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFG 833

Query: 932  KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
             H +K        ++ L C T      K  W+ + + ++G  H  I + G          
Sbjct: 834  THEEK---VRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHTGIQELGHSLLIENTML 890

Query: 990  XXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKL--------------QDFEVKEKD 1032
                 G   C+V +   ++     V  +  P F R                +D  V++ D
Sbjct: 891  VHE--GQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGHEGDDEDDTVEKLD 948

Query: 1033 VAI-----LEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
            V +     L  E N+     + W +DG+ +    +       G +  L I      D G 
Sbjct: 949  VVLGHPVSLSCESNAIPPPKLSWHKDGQKLL-SGDGVVLLPGGQV--LQIARVRKDDAGR 1005

Query: 1087 YSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK 1141
            Y+C   +E+       E+ ++E   E I  + N  V          ++T +    V W +
Sbjct: 1006 YTCQAVNEAGEDHMHFELHILEQFMEEIAAVVNSTV------VLHCDVTGQPTPAVSWLR 1059

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSIN 1197
            DG  +Q     Q++ DG   +L++    + D   Y C    +VG  +    LT++ P   
Sbjct: 1060 DGQPVQLDPQHQISKDG--TQLQLLSVQVSDMAGYLCVAENKVGTVEKLFSLTIQVPPRI 1117

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
                  E  ++  +T + L         ++TW +   ++       ++     + L + +
Sbjct: 1118 SGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPG--GQMLQLPR 1175

Query: 1258 CTEDDQCEYTCVLLDA----KSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
               +D  +Y C   ++    + +  L V V     P++         + GS VTL  +  
Sbjct: 1176 ARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCETH 1235

Query: 1313 AFPQPNDEWIVN 1324
              P+P   W  N
Sbjct: 1236 GVPEPEVTWYKN 1247



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 148/673 (21%), Positives = 252/673 (37%), Gaps = 78/673 (11%)

Query: 1033 VAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
            VA+L  ++      ++ W R G  I     +    K      L I    + D GEY C+ 
Sbjct: 9    VAVLSCKVEGSVRHNLTWYRAGRAIGAHTGR---SKVLPDSSLQISGVQIQDAGEYHCVA 65

Query: 1092 RDESCTAEVTV-VELP--PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
             +    + + V + +P  P ++   Q++  ++G +  F    + G    + F     +  
Sbjct: 66   TNAHGDSRIIVWLHVPEAPSVVIHPQSRVFSRGEEIRFVCSAS-GSPPPQLFWSHGNMLL 124

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLP 1203
            +N  +L I+     L I     +DAG Y+C    E G +  +  LT  E P I  T    
Sbjct: 125  TNRQRLNIN-HYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSEAPRIRVT---Q 180

Query: 1204 EFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
            + I V    DA L  +        V W+K +  +  T       DV    L IR   E D
Sbjct: 181  QAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAG--QDVHHGDLHIRGVQEVD 238

Query: 1263 QCEYTCVLLDAKST-TKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFPQ 1316
               YTCV      T T   +  V   PKI+     D   +  ++ G++V L  + Q  P 
Sbjct: 239  AGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPS 298

Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
            P   W  N   I     T       S SL I  V   D+  Y    EN  G  +V ++  
Sbjct: 299  PLVTWSRNGHPIPPV--TAGFTVLPSGSLRITDVRLIDSKRYTCTAENPAG--NVSLSYN 354

Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW------ISV 1430
            +  +  P  +P    + +             G +  +  VV+ +      W      + +
Sbjct: 355  LHIQAKPRIQPAATLLKA-----------RIGQTVTLPCVVQGEPSPEVTWFHNGLPVGI 403

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
            KN T  +  I   K      +R  A N    S   ET+E    IK              +
Sbjct: 404  KNATPLR--IHQAKLGDQGTYRCVATN----SAGQETSE----IK-------------LD 440

Query: 1491 ITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXX 1546
            I    N     + +F   G P+PK+ W+R+G ++   ++ +                   
Sbjct: 441  ILVRRNSAFAHSFVFVNSGSPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASASHSG 500

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
             + C+A N+ G VE    + +   P I    + +     +     +     GIP P + W
Sbjct: 501  DFTCVATNEAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGCDAFGIPSPTITW 560

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             K+G+ ++    Y    +    ++RI  ++  H+ +++  A N+AG +  E ++ V  K 
Sbjct: 561  SKDGHPVDTPGVY---LQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKH 617

Query: 1667 SKPEGPVIMREIS 1679
             K + P+  R ++
Sbjct: 618  IK-QPPLTTRTLT 629



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 76/321 (23%), Positives = 132/321 (41%), Gaps = 26/321 (8%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G+  +L C++      ++ W   G  I      S  +        S L+I+ V+    G 
Sbjct: 7   GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPD------SSLQISGVQIQDAGE 60

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           Y  VA N  G++ + + L +     E P V+   +S +  +GE +       G+P P + 
Sbjct: 61  YHCVATNAHGDSRIIVWLHVP----EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLF 116

Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
           W   N  +     + + + + +  +K    +D G YT  A N  G+A  S  +T  E   
Sbjct: 117 WSHGNM-LLTNRQRLNINHYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSE--- 172

Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
               P + + + Q I V       L  + T  P P + W++    +  +    Q  D  +
Sbjct: 173 ---APRIRVTQ-QAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQ--DVHH 226

Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKVTFVKHLQKSYE--TEEGK 944
            +L I  V  E+D+G Y CVAS+ AG ++    + +  + K+  V    K+ +   E G 
Sbjct: 227 GDLHIRGV-QEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGT 285

Query: 945 TVILECQTSHTVS--TKWYHN 963
            V+L C+     S    W  N
Sbjct: 286 EVVLPCEAQGNPSPLVTWSRN 306



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 82/349 (23%), Positives = 139/349 (39%), Gaps = 40/349 (11%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P+ S  P    V  G   +L C    IP P ++W   G  +    ++S    +   + 
Sbjct: 1971 VGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPL----DVSQLSGAFRLLS 2026

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---------PPQVIEPLK 742
               L + +     EG +   AVN  GE    I + ++ G+ +         PP + + + 
Sbjct: 2027 SGSLVLLSPSNEDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVT 2086

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKV-- 797
            ++   +    +L   V G P+PT+ W K    +      S G T+ +    +L+   V  
Sbjct: 2087 AVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLS-----SRGGTYRVLPTGLLEITSVLP 2141

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARV 856
               G YT  A NS G+A     ++V+E  E     P+     +E+  V   GT+ L    
Sbjct: 2142 SHAGRYTCSARNSAGVAHKHVSLSVQESPEIR---PMA----EEVQVVLHHGTV-LPCEA 2193

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
               P PSI+W R    I+    ++   +G    L  + V    D+G Y+C+A N AG + 
Sbjct: 2194 QGFPRPSISWQREGVPIATGHRLSLLSNGA---LKFSRVTLG-DAGTYQCLAKNEAGAAV 2249

Query: 917  HGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHN 963
               ++ + V  +  +   Q      +G   +L C  Q S      W  N
Sbjct: 2250 GQTKLVLHVPPL--ISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKN 2296



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 3/173 (1%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
            ++T    + + L+C   G P P ++W  +    + A      R               Y 
Sbjct: 2385 DVTLNKGQSLALSCHAQGTPSPVISWTVNNSPRQGAAVDEAGRSSLIIENVTTSDAGTYV 2444

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            C+A N  G V T   V +++ PV+   +  + Q    G   ++   I G P P + W ++
Sbjct: 2445 CVAENRVGSVRTLSFVRVREPPVLK-GDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRD 2503

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            GN L   + + I      S++       +H  +Y   A N AGT+   + LKV
Sbjct: 2504 GNALL--RSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAGTAERTIALKV 2554



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 43/187 (22%), Positives = 75/187 (40%), Gaps = 7/187 (3%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXX 1545
            ++ +T   N  + L C+    P P + WY+D  K++      +                 
Sbjct: 1798 VRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPEDS 1857

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y C+  N  G       V I   P+I  S+ ++     +G + L+   +E      V 
Sbjct: 1858 GLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVTTH--IGQDALLPCEVEEESHATVT 1915

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W K+G  +  D  Y + ++     +RI  ++ S + +Y    SN AG+    V L+V+  
Sbjct: 1916 WRKDGFPITQDNRYTLLSEGS---LRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVG 1972

Query: 1666 PSKPEGP 1672
            PS   GP
Sbjct: 1973 PSISPGP 1979



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 13/191 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F + P    +++G  + L C     P P I+W        P +  +V  E+      S
Sbjct: 2377 PAFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNS---PRQGAAVD-EAGR----S 2428

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752
             L I NV     GTY  VA NR G       +++    +EPP +  +   S  V QG S 
Sbjct: 2429 SLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRV----REPPVLKGDAHMSQTVIQGSST 2484

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            IL   + G+P P + W ++   +            S+ I        EG Y   AEN  G
Sbjct: 2485 ILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAG 2544

Query: 813  IAETSAVITVE 823
             AE +  + V+
Sbjct: 2545 TAERTIALKVQ 2555



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 6/189 (3%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXX 1541
            +E+ ++ I    N  + L C   G P P V+W RDG+  +L       ++          
Sbjct: 1026 LEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLLSVQ 1085

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C+A N  G VE    + IQ  P I+   E+     + G    +   ++  PP
Sbjct: 1086 VSDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIE-GHTASLLCDVQAYPP 1144

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            PE+ W ++G  L      +I    +  ++++   +   + +Y   A+N+AG     + L 
Sbjct: 1145 PEITWTRDGQILAFGTGVHILPGGQ--MLQLPRARLEDAGQYVCTATNSAGQDQKSILLS 1202

Query: 1662 VYDKPS-KP 1669
            VY +P+ KP
Sbjct: 1203 VYVRPTMKP 1211



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 7/179 (3%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXX 1547
            N+T+       L+C   G  +  +TWYR G+ +   T ++                    
Sbjct: 1    NVTSSVGAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSLQISGVQIQDAGE 60

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            Y C+A N HG+      + + + P + I  +   +    G+E        G PPP++ W 
Sbjct: 61   YHCVATNAHGDSRIIVWLHVPEAPSVVIHPQ--SRVFSRGEEIRFVCSASGSPPPQLFWS 118

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                 L N +  NI       V+ IK      +  YT  A+N AG +S  V+L   + P
Sbjct: 119  HGNMLLTNRQRLNI---NHYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSEAP 174



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 52/219 (23%), Positives = 92/219 (42%), Gaps = 20/219 (9%)

Query: 1472 KVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
            K IK+  + + T+   + N  +T    +++E  C   G P P+V W RDG+ L      +
Sbjct: 616  KHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPH 675

Query: 1530 ----ENRXXXXXXXXXXXXXXXYKCIAFNDHG----------EVETSCVVGIQQKPVITI 1575
                E+                Y+C+A N+ G          +V T  VV +   P I  
Sbjct: 676  VEFHEDGQVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSP-PTIKG 734

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
             +E  +    +G   L++  +EG P P + W K+   + +  +  +T       +R+  +
Sbjct: 735  PSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQ--LTYTRGGQALRLGSV 792

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPV 1673
            +   +  YT  A+N AGT+    +L V   P  + + PV
Sbjct: 793  QGDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPV 831



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 45/211 (21%), Positives = 86/211 (40%), Gaps = 7/211 (3%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--RXXXXX 1537
            ++P +    + I      D  L C   G P P V W++   ++ +     ++        
Sbjct: 172  EAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHGDLHI 231

Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI---TISNEDIKQKHKVGDEWLVTA 1594
                      Y C+A +  G    + ++ +   P I   T +++ +K   +VG E ++  
Sbjct: 232  RGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPC 291

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
              +G P P V W +NG+ +        T     S +RI +++   S +YT  A N AG  
Sbjct: 292  EAQGNPSPLVTWSRNGHPIP-PVTAGFTVLPSGS-LRITDVRLIDSKRYTCTAENPAGNV 349

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            S+   L +  KP       +++    ++VT+
Sbjct: 350  SLSYNLHIQAKPRIQPAATLLKARIGQTVTL 380



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  ++F C   G P PQ+ W     ++   Q   +    ++   L I+   PEDAG +TC
Sbjct: 98  GEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNI----NHYGVLTIKGALPEDAGNYTC 153

Query: 584 VAKNAAGFASSTTEL-IVEAP 603
           +A N AG AS +  L   EAP
Sbjct: 154 LATNEAGVASQSVSLTFSEAP 174



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 110/543 (20%), Positives = 194/543 (35%), Gaps = 54/543 (9%)

Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLT 1217
            L+I    + DAGEY C      G+S+    L V E PS+   +     +        ++ 
Sbjct: 48   LQISGVQIQDAGEYHCVATNAHGDSRIIVWLHVPEAPSV--VIHPQSRVFSRGEEIRFVC 105

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
                     + W     ++ + ++  +        L I+    +D   YTC+  +     
Sbjct: 106  SASGSPPPQLFWSHGNMLLTNRQRLNINH---YGVLTIKGALPEDAGNYTCLATNEAGVA 162

Query: 1278 KLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
               V +     P+I   ++   +  G+D  L       P P   W      +        
Sbjct: 163  SQSVSLTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQ 222

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
              D     L I+ V+  DAG Y     +  G A   + + +   P   G  +  +    +
Sbjct: 223  --DVHHGDLHIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMA 280

Query: 1397 INICWDEP---ENTGN-STIIYYVVEYQEID-TTEWISVKNITKTQTSIQNLKTNSSYRF 1451
            + +  +     E  GN S ++ +      I   T   +V  +      I +++   S R+
Sbjct: 281  VEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTV--LPSGSLRITDVRLIDSKRY 338

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
               A N      A   +  Y +  + K   P ++     +     + + L C+  G P P
Sbjct: 339  TCTAENP-----AGNVSLSYNLHIQAK---PRIQPAATLLKARIGQTVTLPCVVQGEPSP 390

Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            +VTW+ +G  +    AT                   Y+C+A N  G+ ETS +       
Sbjct: 391  EVTWFHNGLPVGIKNAT-----PLRIHQAKLGDQGTYRCVATNSAGQ-ETSEI------- 437

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
                   DI  +           V  G P P++ W++NG  LE   E +  +  +   + 
Sbjct: 438  -----KLDILVRRNSAFAHSFVFVNSGSPRPKIRWFRNG--LEIHPEQSDFSVGEDGALV 490

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            I+    SHS  +T  A+N AG+   +  LKV + P     P I  +    ++T+  K PL
Sbjct: 491  IRAASASHSGDFTCVATNEAGSVERKTRLKV-NVP-----PEIQDDTQPLNLTVTLKQPL 544

Query: 1692 DDG 1694
              G
Sbjct: 545  TLG 547



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 3/140 (2%)

Query: 515  KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
            ++ P     GS V   C+  G P P +TW +    +   ++  +   D     L + +V 
Sbjct: 1613 QVEPVTIVQGSLVTLSCEARGVPPPTLTWLKDGQPLSLHRNLLL---DGQETRLQLPDVG 1669

Query: 575  PEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP 634
            P DAG ++CVA N AG ++ T  L V  P    GS                     G+PP
Sbjct: 1670 PSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729

Query: 635  TFSKKPKAQYVDEGSDILLE 654
                  K  +  E  DI+ E
Sbjct: 1730 PTLTWLKDGHPLERRDIVQE 1749



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 31/70 (44%), Positives = 34/70 (48%), Gaps = 5/70 (7%)

Query: 535 GYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
           G PRP+I WFR    I P Q DF +  D      LVIR      +G FTCVA N AG   
Sbjct: 459 GSPRPKIRWFRNGLEIHPEQSDFSVGED----GALVIRAASASHSGDFTCVATNEAGSVE 514

Query: 594 STTELIVEAP 603
             T L V  P
Sbjct: 515 RKTRLKVNVP 524



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 28/137 (20%), Positives = 59/137 (43%), Gaps = 3/137 (2%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXX 1538
            +SP +    + +    +    L C   G P+P ++W R+G  + T  + +  +       
Sbjct: 2168 ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQREGVPIATGHRLSLLSNGALKFS 2227

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                     Y+C+A N+ G       + +   P+I+ +  ++      G + L++   +G
Sbjct: 2228 RVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPPLISPAQTELSVIQ--GFQALLSCAAQG 2285

Query: 1599 IPPPEVIWYKNGNKLEN 1615
             P P++ W KNG+ + N
Sbjct: 2286 SPDPKISWEKNGSPVPN 2302



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 5/101 (4%)

Query: 514  EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
            +++R    P    +  EC  +  P P I W++    ++     Q          L I+EV
Sbjct: 1796 DEVRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQ---YLEIQEV 1852

Query: 574  FPEDAGTFTCVAKNAAGFAS--STTELIVEAPLSDHGSEMT 612
             PED+G ++CV  N AG +S   T E+++   + +  SE+T
Sbjct: 1853 KPEDSGLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVT 1893



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            +M P F E         G ++   C  +G P P I+W   T    P Q   +  D+   +
Sbjct: 2374 NMRPAFKELPGDVTLNKGQSLALSCHAQGTPSPVISW---TVNNSPRQGAAV--DEAGRS 2428

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +L+I  V   DAGT+ CVA+N  G   + + + V  P
Sbjct: 2429 SLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREP 2465



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
           H   G+    ECQ  G P P + WF+    +  S  F     D +   L IR V   DAG
Sbjct: 184 HVSVGADAVLECQATGAPPPLVRWFKGEFEVG-STPFAG--QDVHHGDLHIRGVQEVDAG 240

Query: 580 TFTCVAKNAAGFASSTTELIVEA 602
            +TCVA + AG A+ T  L V A
Sbjct: 241 RYTCVASSPAGTATGTVILKVGA 263



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 42/172 (24%), Positives = 63/172 (36%), Gaps = 19/172 (11%)

Query: 430  VAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLN 489
            V++   A  L+    L +L  SN+D  Y +     E G        +E    + + +   
Sbjct: 2015 VSQLSGAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAG--------EERRVIEVILQDGQ 2066

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
              +        P S E  +  +   KL P   P        C V G P+P + W +  A 
Sbjct: 2067 TDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLP--------CHVHGRPQPTVFWTKGGAK 2118

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +         Y       L I  V P  AG +TC A+N+AG A     L V+
Sbjct: 2119 LSSRGGT---YRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAHKHVSLSVQ 2167



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G TV   C V+G P P++TWF     +             N   L I +    D GT+ C
Sbjct: 375 GQTVTLPCVVQGEPSPEVTWFHNGLPV----------GIKNATPLRIHQAKLGDQGTYRC 424

Query: 584 VAKNAAGFASSTTEL 598
           VA N+AG  +S  +L
Sbjct: 425 VATNSAGQETSEIKL 439



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 11/125 (8%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESC---TAEVTVVELPPEIITRLQ-NQKVNKGNKATFEIE 1129
            L I N +  D G Y C+  +      T     V  PP +      +Q V +G+    +  
Sbjct: 2430 LIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCP 2489

Query: 1130 LTKGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCT 1186
            +  GD   +++W +DG+ +  S+ IQ  ++G    L IY  +++   GEY C   N   T
Sbjct: 2490 I-HGDPSPVLQWLRDGNALLRSHRIQALLNG---SLVIYSVNVNTHEGEYQCLAENEAGT 2545

Query: 1187 AILTV 1191
            A  T+
Sbjct: 2546 AERTI 2550



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+     C+VEG  R  +TW+R    I           D   ++L I  V  +DAG + C
Sbjct: 7   GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPD---SSLQISGVQIQDAGEYHC 63

Query: 584 VAKNAAGFASSTTEL-IVEAP 603
           VA NA G +     L + EAP
Sbjct: 64  VATNAHGDSRIIVWLHVPEAP 84



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           G+ V   C+ +G P P +TW R    I P +  F +        +L I +V   D+  +T
Sbjct: 284 GTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTVLPS----GSLRITDVRLIDSKRYT 339

Query: 583 CVAKNAAGFASSTTELIVEA 602
           C A+N AG  S +  L ++A
Sbjct: 340 CTAENPAGNVSLSYNLHIQA 359


>UniRef50_Q4SK55 Cluster: Chromosome 2 SCAF14570, whole genome shotgun
            sequence; n=3; Clupeocephala|Rep: Chromosome 2 SCAF14570,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 1464

 Score =  169 bits (410), Expect = 1e-39
 Identities = 181/750 (24%), Positives = 311/750 (41%), Gaps = 71/750 (9%)

Query: 633  PPTF---SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            P TF   S++   + V E  ++LL C  V+  +  + W   G E+    N ++  E  M 
Sbjct: 671  PVTFTYISEEDLFKSVVEQEELLLSCE-VSRADGVVQWYKDGTELQQGHNTTIQAEGTMR 729

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQ 748
                 LKI + +    GTYT     R G+     V+  K   +EPP  +I P + + + +
Sbjct: 730  Y----LKIHSAQLSGTGTYTC----RTGDN----VIIFKVNVREPPVMIIHPREDVHLER 777

Query: 749  G--ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVY 803
               E +ILS ++   P   ++W K+ + ++    +  K +G    + IL   +V+D G Y
Sbjct: 778  HVPEEIILSCEL-SRPNGIVSWYKDGQKLQESENIKLKFEGPYRRLKILC-SRVEDSGEY 835

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
                 +          + + EP      P        E+  +    + L   ++R P   
Sbjct: 836  VCDTADDSIFFH----LNITEPPVRILSPS---QSQMELCQQTSERMVLSCEISR-PNAV 887

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + WYRN   +  +  +    DG    L+I     + DS +Y C  ++     S    V I
Sbjct: 888  VRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVK-DSAEYVCDTTDD----SMTFFVNI 942

Query: 924  DVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980
                V F++   +  + E   G+T++L+C+ S +     W  N +E+    +  I+++G 
Sbjct: 943  AEPPVRFIRSRKMASAIEKVAGETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGA 1002

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL---QDFEVKEKDVAILE 1037
                          G   C  KD     ++ VKE   + I      +   +   D  ILE
Sbjct: 1003 IRQLTIHSLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILE 1062

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
             E++   A V W R+G+I+KP  ++   ++   +RKL +      D G Y C   D+   
Sbjct: 1063 CEVSRPNATVQWLRNGKILKPD-SRIKIDRYDVVRKLVLSGLQPSDSGTYVCDAIDDQLV 1121

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157
              V V E+  + I  L+N    KG+  T   E++K    V+W KDG E+  S    +   
Sbjct: 1122 TAVEVQEMMVKFIKPLENTACVKGSSLTLRCEISKLKGDVQWLKDGQEVSSSRRHTIRAQ 1181

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
            G+++ + IY    +D+G Y CE  + + +A +TVE   ++ T                  
Sbjct: 1182 GRERSITIYQLVEEDSGVYVCESTHDRTSATVTVETARLSMT------------------ 1223

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
                +  L + W    + I+ ++   + +  +KR L I KC   D   YTC   DA  TT
Sbjct: 1224 ----EHKLSLQW-NNGTEIKPSKDLRIYAMGRKRFLQILKCNVIDSGIYTCDAGDA--TT 1276

Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
               VEV E P  IV    +      S V +L    + P+ +  W     +I   +  +  
Sbjct: 1277 SCNVEVYELPVNIVKPLEDKTAFEMSRV-ILDCTVSNPRCSIRWYKGCTVILPSERFEIC 1335

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRL-ENNC 1366
             +     L I++V   DAG Y +++ E +C
Sbjct: 1336 SEGGYRKLIIQQVALDDAGTYSVQVGEYSC 1365



 Score =  146 bits (353), Expect = 8e-33
 Identities = 121/513 (23%), Positives = 214/513 (41%), Gaps = 22/513 (4%)

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            +P   +TWY++   +  +   T   +G    LV  +      SG Y C  ++ A +    
Sbjct: 608  DPNAQVTWYKDGIRLHKAAGHTILAEGSKRMLVFESAVLS-HSGIYYCKTTDDAVEFHVD 666

Query: 919  ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQ 977
            A  T      T++          E + ++L C+ S      +WY +  E+    +  I  
Sbjct: 667  A--TAPPVTFTYISEEDLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQA 724

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK--DVAI 1035
            EG               G   C   D      + V+E     I   +D  ++    +  I
Sbjct: 725  EGTMRYLKIHSAQLSGTGTYTCRTGDNVIIFKVNVREPPVMIIHPREDVHLERHVPEEII 784

Query: 1036 LEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            L  E++     V W +DG+ ++  +N K  FE  G  R+L I  + V D GEY C   D+
Sbjct: 785  LSCELSRPNGIVSWYKDGQKLQESENIKLKFE--GPYRRLKILCSRVEDSGEYVCDTADD 842

Query: 1095 SCTAEVTVVELPPEIITRLQNQKV---NKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151
            S    + + E P  I++  Q+Q         +     E+++ +A+VRW+++G E++ +N+
Sbjct: 843  SIFFHLNITEPPVRILSPSQSQMELCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNN 902

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVP 1209
            + L +DG  ++L I    + D+ EY C+  +   T  + + EP + F  + ++   I   
Sbjct: 903  LILEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKV 962

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
            A     L  E+     +VTW +    +ED+   T++ D   R L I   T     +Y C 
Sbjct: 963  AGETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQYVC- 1021

Query: 1270 LLDAK-STTKLKVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
              DAK       V+V E P +I+    +   + +  G D+ L  +    P    +W+ N 
Sbjct: 1022 --DAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSR-PNATVQWLRNG 1078

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            KI+K     K         L +  ++ +D+G Y
Sbjct: 1079 KILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTY 1111



 Score =  126 bits (303), Expect = 9e-27
 Identities = 132/656 (20%), Positives = 263/656 (40%), Gaps = 31/656 (4%)

Query: 635  TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            T  +  + + V+ G  ++L C  ++ P   + W   G  +      ++  E    M    
Sbjct: 584  TLCEAERKKSVEAGEPLMLRCE-ISDPNAQVTWYKDGIRLHKAAGHTILAEGSKRMLVFE 642

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
              + +         T  AV    +A+ P V      E       E L   +V Q E ++L
Sbjct: 643  SAVLSHSGIYYCKTTDDAVEFHVDATAPPVTFTYISE-------EDLFKSVVEQ-EELLL 694

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            S +V       + W K+   ++     +     ++  LK    +  G  T      + + 
Sbjct: 695  SCEV-SRADGVVQWYKDGTELQQGHNTTIQAEGTMRYLKIHSAQLSGTGTYTCRTGDNVI 753

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITWYRNNEII 873
                 + V EP      P + I+  +++ ++     +++     + P   ++WY++ + +
Sbjct: 754  IFK--VNVREP------PVMIIHPREDVHLERHVPEEIILSCELSRPNGIVSWYKDGQKL 805

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
              SE I   F+G    L I     E DSG+Y C  ++ +        +T    ++     
Sbjct: 806  QESENIKLKFEGPYRRLKILCSRVE-DSGEYVCDTADDS--IFFHLNITEPPVRILSPSQ 862

Query: 934  LQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
             Q     +  + ++L C+ S      +WY N  E+   ++  +  +G             
Sbjct: 863  SQMELCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVK 922

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---DVAILEVEINSETADVVW 1049
            D     C   D   +  + + E    FIR  +     EK   +  +L+ E++   A+V W
Sbjct: 923  DSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKVAGETLVLDCEVSRSNAEVTW 982

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
            +R+GE ++  +N    E  G IR+L I + +V   G+Y C  +D+     V V E P +I
Sbjct: 983  KRNGEEMEDSRNITILED-GAIRQLTIHSLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQI 1041

Query: 1110 ITRL---QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            I      ++  +  G+    E E+++ +A V+W ++G  ++  + I++      +KL + 
Sbjct: 1042 IGNSGHPEHHTLVAGDDLILECEVSRPNATVQWLRNGKILKPDSRIKIDRYDVVRKLVLS 1101

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
                 D+G Y C+  + +    + V+E  + F   L     V  ++   L  EI     D
Sbjct: 1102 GLQPSDSGTYVCDAIDDQLVTAVEVQEMMVKFIKPLENTACVKGSS-LTLRCEISKLKGD 1160

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            V W K    +  + + T+ +  ++R++ I +  E+D   Y C     +++  + VE
Sbjct: 1161 VQWLKDGQEVSSSRRHTIRAQGRERSITIYQLVEEDSGVYVCESTHDRTSATVTVE 1216



 Score =  126 bits (303), Expect = 9e-27
 Identities = 165/742 (22%), Positives = 297/742 (40%), Gaps = 70/742 (9%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            +I+L C L + P   ++W   G+++   ENI +  E         LKI   +    G Y 
Sbjct: 782  EIILSCEL-SRPNGIVSWYKDGQKLQESENIKLKFEGPYRR----LKILCSRVEDSGEY- 835

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIV---RQGESVILSAQVVGNPRPT 765
               V    + S+   L I     EPP +++ P +S +    +  E ++LS ++   P   
Sbjct: 836  ---VCDTADDSIFFHLNIT----EPPVRILSPSQSQMELCQQTSERMVLSCEI-SRPNAV 887

Query: 766  ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            + W +N   V+    L  + DG    + I K   VKD   Y     +       +  + +
Sbjct: 888  VRWYRNGLEVEENNNLILEVDGVYRRLIIPKTT-VKDSAEYVCDTTDDS----MTFFVNI 942

Query: 823  EEPTEENAEPPLFINRFQEITVKEK---GTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
             EP      P  FI   +  +  EK    T+ L   V+R+    +TW RN E +  S  I
Sbjct: 943  AEP------PVRFIRSRKMASAIEKVAGETLVLDCEVSRSNA-EVTWKRNGEEMEDSRNI 995

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
            T   DG   +L I ++ +   SG Y C A +         +V     ++       + + 
Sbjct: 996  TILEDGAIRQLTIHSL-TVAHSGQYVCDAKDDV--MDFLVKVKEPPVQIIGNSGHPEHHT 1052

Query: 940  TEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
               G  +ILEC+ S   +T +W  N K +      +I +               D G   
Sbjct: 1053 LVAGDDLILECEVSRPNATVQWLRNGKILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTYV 1112

Query: 999  CIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058
            C   D +  T + V+E + +FI+ L++    +     L  EI+    DV W +DG+ +  
Sbjct: 1113 CDAIDDQLVTAVEVQEMMVKFIKPLENTACVKGSSLTLRCEISKLKGDVQWLKDGQEVSS 1172

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKV 1118
             + ++    +G  R + I      D G Y C    +  +A VTV                
Sbjct: 1173 SR-RHTIRAQGRERSITIYQLVEEDSGVYVCESTHDRTSATVTV---------------- 1215

Query: 1119 NKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
                  T  + +T+    ++W  +G+EI+ S  +++   G+K+ L+I  C++ D+G Y+C
Sbjct: 1216 -----ETARLSMTEHKLSLQW-NNGTEIKPSKDLRIYAMGRKRFLQILKCNVIDSGIYTC 1269

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
            + G++  +  + V E  +N    L +      +    L   + +    + WYK  +VI  
Sbjct: 1270 DAGDATTSCNVEVYELPVNIVKPLEDKTAFEMSR-VILDCTVSNPRCSIRWYKGCTVILP 1328

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298
            +E+F + S+   R LII++   DD   Y+  + +   + KL VE       +V    +  
Sbjct: 1329 SERFEICSEGGYRKLIIQQVALDDAGTYSVQVGEYSCSAKLTVEAQIL--SVVRELEDVE 1386

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +   S+     +  A       W +N + ++     +         L +K+      G  
Sbjct: 1387 VTAPSEACFECEVSAPVVRAPVWSLNGECLQSSSCIRVEKTGAVHRLVLKQTSVDMNG-- 1444

Query: 1359 KLRLENNCGHADVEMNVTILDK 1380
               +E  CG+A  +  + +L K
Sbjct: 1445 --EIEFTCGNAKSKAQLQVLSK 1464



 Score =  115 bits (277), Expect = 1e-23
 Identities = 107/456 (23%), Positives = 189/456 (41%), Gaps = 23/456 (5%)

Query: 920  RVTIDVE----KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHRE 974
            R  ++VE    ++T +   ++    E G+ ++L C+ S       WY +   +       
Sbjct: 570  RFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPNAQVTWYKDGIRLHKAAGHT 629

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE----FIRKLQDFE-VK 1029
            I+ EG               G+  C  K  + +    V  T P     +I +   F+ V 
Sbjct: 630  ILAEGSKRMLVFESAVLSHSGIYYC--KTTDDAVEFHVDATAPPVTFTYISEEDLFKSVV 687

Query: 1030 EKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            E++  +L  E++     V W +DG  ++   N    +  G +R L I +  +   G Y+C
Sbjct: 688  EQEELLLSCEVSRADGVVQWYKDGTELQQGHNT-TIQAEGTMRYLKIHSAQLSGTGTYTC 746

Query: 1090 ILRDESCTAEVTVVELPPEIITRLQNQKVNKG--NKATFEIELTKGDALVRWFKDGSEIQ 1147
               D     +V V E P  II   ++  + +    +     EL++ + +V W+KDG ++Q
Sbjct: 747  RTGDNVIIFKVNVREPPVMIIHPREDVHLERHVPEEIILSCELSRPNGIVSWYKDGQKLQ 806

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
             S +I+L  +G  ++LKI    ++D+GEY C+  +      L + EP +         + 
Sbjct: 807  ESENIKLKFEGPYRRLKILCSRVEDSGEYVCDTADDSIFFHLNITEPPVRILSPSQSQME 866

Query: 1208 VPANTDA--YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265
            +   T     L+ EI      V WY+    +E+     L  D   R LII K T  D  E
Sbjct: 867  LCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVKDSAE 926

Query: 1266 YTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDE--WI 1322
            Y C   D   T    V + E P + +   +    I++ +  TL++D +   + N E  W 
Sbjct: 927  YVCDTTDDSMT--FFVNIAEPPVRFIRSRKMASAIEKVAGETLVLDCEV-SRSNAEVTWK 983

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
             N + ++  ++     D     LTI  +    +G Y
Sbjct: 984  RNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQY 1019



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 207/1010 (20%), Positives = 367/1010 (36%), Gaps = 100/1010 (9%)

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKK 796
            +K   V +G+       V G P+P I W K+ + +    + L  +      ++ +L  K+
Sbjct: 102  VKMFAVTEGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQ 161

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             KD GVY   A N+ G   ++  ++V+EP      P  F     ++ V E+    L   V
Sbjct: 162  -KDNGVYVCAASNTAGQTLSAVHLSVKEP------PVRFKQPLIDLEVWERDLAVLECEV 214

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              + VP ITWY  +  + P         G    L I ++  + D G Y C   +  G+S 
Sbjct: 215  PEDSVP-ITWYLEDRRLQPGAKYGMEEWGTKRRLTIRDIGVD-DDGIYLCEMPD-GGRSI 271

Query: 917  HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREI 975
              A V +   K T ++ L +  +  EG+      +     +   WY +  E+    H+ I
Sbjct: 272  --AEVAV---KGTILRKLPRKVDVLEGENAAYCVEVEKEEMDIHWYKDGVELR-ETHQTI 325

Query: 976  IQE-GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET--IPEFIRKLQDFEVKEKD 1032
            I+  GR            D G++  +V   +TS+ L VK     P           +  +
Sbjct: 326  IKSFGRTHILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSARHCPPSCPVGVQINTERAN 385

Query: 1033 VAIL-----EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
             A+L     +    +  +  V ER  E+    +             + I   SV  E +Y
Sbjct: 386  AALLSWVPAQDSRRNPPSGYVLERQ-EVGTGSQEWLQCLTTDSATSVEILGDSVPCEADY 444

Query: 1088 SCILRDESCTAEVTVVELPPEI----ITR----LQNQKVNKGNKATFEIELTKGDALVRW 1139
               +   +   +   VE P  +    + R    LQ+  V +G  A F IEL+    +  W
Sbjct: 445  RFRICSVNKYGKSNNVEFPRAVHLVPVARIQAPLQDALVPEGQDAFFSIELS-ASVIGTW 503

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDC-DLDDAGEYSCEVGNSKCTAILTVE------ 1192
            F +G+++Q      +      Q L+I    D D+  E +      + +A L ++      
Sbjct: 504  FLNGTQLQEDERYSMRRTRTHQSLRIRGVRDTDNGAEITFIAYGIRDSAALYIQGVYCCD 563

Query: 1193 --EPSINFTLR---LPEFIL----------VPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237
              +  I F +    LP  I           V A     L  EI D    VTWYK    + 
Sbjct: 564  AIDDVIRFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPNAQVTWYKDGIRLH 623

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297
                 T++++  KR L+           Y C   D     +  V+    PP    Y  E 
Sbjct: 624  KAAGHTILAEGSKRMLVFESAVLSHSGIYYCKTTD--DAVEFHVDATA-PPVTFTYISEE 680

Query: 1298 RIKRG--SDVTLLVDYQAFPQPN-DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
             + +       LL+  +        +W  +   +++  +T    +     L I   + + 
Sbjct: 681  DLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQAEGTMRYLKIHSAQLSG 740

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILE--IDSSSINICWDEPENTGN 1409
             G Y  R  +N     +   V + + P     P +   LE  +    I  C    E +  
Sbjct: 741  TGTYTCRTGDNV----IIFKVNVREPPVMIIHPREDVHLERHVPEEIILSC----ELSRP 792

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + I+ +  + Q++  +E I +    K +   + LK   S   R     E     A ++  
Sbjct: 793  NGIVSWYKDGQKLQESENIKL----KFEGPYRRLKILCS---RVEDSGEYVCDTADDSIF 845

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
            ++  I E  ++  +  +    +  + +E + L+C     P   V WYR+G +++      
Sbjct: 846  FHLNITEPPVRILSPSQSQMELCQQTSERMVLSCEISR-PNAVVRWYRNGLEVEENNNLI 904

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-HKVGD 1588
                                     D  +   +  V I + PV  I +  +     KV  
Sbjct: 905  LEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKVAG 964

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
            E LV          EV W +NG ++E+ +   I        + I  L  +HS +Y  +A 
Sbjct: 965  ETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQYVCDAK 1024

Query: 1649 NTAGTSSVEV---TLKVYDKPSKPEGPVIMR--------EISRESVTIEW 1687
            +      V+V    +++      PE   ++         E+SR + T++W
Sbjct: 1025 DDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSRPNATVQW 1074



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 114/469 (24%), Positives = 191/469 (40%), Gaps = 53/469 (11%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            S  P+   +  G D++LEC  V+ P   + WL  G+ + PD  I +    D +     L 
Sbjct: 1045 SGHPEHHTLVAGDDLILECE-VSRPNATVQWLRNGKILKPDSRIKI----DRYDVVRKLV 1099

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            ++ ++    GTY   A++ +      +V  ++  E    + I+PL++    +G S+ L  
Sbjct: 1100 LSGLQPSDSGTYVCDAIDDQ------LVTAVEVQEMMV-KFIKPLENTACVKGSSLTLRC 1152

Query: 757  QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            ++    +  + W K+ + V      S    H  TI    + +   +Y L  E+S      
Sbjct: 1153 EI-SKLKGDVQWLKDGQEV------SSSRRH--TIRAQGRERSITIYQLVEEDSG----- 1198

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
               + V E T +             +TV+   T +L   +T + + S+ W    EI  PS
Sbjct: 1199 ---VYVCESTHDRTSAT--------VTVE---TARL--SMTEHKL-SLQWNNGTEI-KPS 1240

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            + +     G    L I   +  IDSG Y C     AG ++    V +    V  VK L+ 
Sbjct: 1241 KDLRIYAMGRKRFLQILKCNV-IDSGIYTC----DAGDATTSCNVEVYELPVNIVKPLED 1295

Query: 937  SYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                E  + VIL+C  S+   S +WY     I   +  EI  EG             D G
Sbjct: 1296 KTAFEMSR-VILDCTVSNPRCSIRWYKGCTVILPSERFEICSEGGYRKLIIQQVALDDAG 1354

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGE 1054
                 V +   S  L V+  I   +R+L+D EV     A  E E+++      VW  +GE
Sbjct: 1355 TYSVQVGEYSCSAKLTVEAQILSVVRELEDVEVTAPSEACFECEVSAPVVRAPVWSLNGE 1414

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
             ++   +    EK G + +L ++ TSV   GE      +    A++ V+
Sbjct: 1415 CLQ-SSSCIRVEKTGAVHRLVLKQTSVDMNGEIEFTCGNAKSKAQLQVL 1462



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 119/598 (19%), Positives = 225/598 (37%), Gaps = 39/598 (6%)

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGD 1134
            + +++ +G Y C   D+     V V  LP  I T  + ++   V  G       E++  +
Sbjct: 551  SAALYIQGVYCCDAIDDVIRFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPN 610

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
            A V W+KDG  +  +    +  +G K+ L      L  +G Y C+  +      +    P
Sbjct: 611  AQVTWYKDGIRLHKAAGHTILAEGSKRMLVFESAVLSHSGIYYCKTTDDAVEFHVDATAP 670

Query: 1195 SINFTLRLPE--FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
             + FT    E  F  V    +  L+ E+      V WYK  + ++     T+ ++   R 
Sbjct: 671  PVTFTYISEEDLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQAEGTMRY 730

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
            L I          YTC   D  +    KV V E P  I+    +  ++R     +++  +
Sbjct: 731  LKIHSAQLSGTGTYTCRTGD--NVIIFKVNVREPPVMIIHPREDVHLERHVPEEIILSCE 788

Query: 1313 AFPQPND--EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
               +PN    W  + + +++ ++ K   +     L I      D+G Y       C  AD
Sbjct: 789  -LSRPNGIVSWYKDGQKLQESENIKLKFEGPYRRLKILCSRVEDSGEYV------CDTAD 841

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
              +    L+   PP +  IL    S + +C    + T    ++   +         W   
Sbjct: 842  DSIFFH-LNITEPPVR--ILSPSQSQMELC----QQTSERMVLSCEISRPNA-VVRWY-- 891

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE----TTE----YYKVIKETKIQSP 1482
            +N  + + +  NL       +R   + +  + D++E    TT+    ++  I E  ++  
Sbjct: 892  RNGLEVEEN-NNLILEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFI 950

Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
               K    I     E + L C        +VTW R+G++++ ++                
Sbjct: 951  RSRKMASAIEKVAGETLVLDCEVSR-SNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIH 1009

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIP 1600
                 +      D  +     +V +++ PV  I N    + H +  GD+ ++   +   P
Sbjct: 1010 SLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSR-P 1068

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
               V W +NG  L+ D    I   +    + +  L+ S S  Y  +A +    ++VEV
Sbjct: 1069 NATVQWLRNGKILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTYVCDAIDDQLVTAVEV 1126



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 87/390 (22%), Positives = 166/390 (42%), Gaps = 30/390 (7%)

Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDC 1168
            T+++   V +G  A F   +T K    + W KDG  I       L  D +    LK+  C
Sbjct: 100  TKVKMFAVTEGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYC 159

Query: 1169 DLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
               D G Y C   N+    +    L+V+EP + F   L +  +   +  A L  E+P+++
Sbjct: 160  KQKDNGVYVCAASNTAGQTLSAVHLSVKEPPVRFKQPLIDLEVWERDL-AVLECEVPEDS 218

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVE- 1282
            + +TWY +   ++   K+ +     KR L IR    DD   Y C + D  +S  ++ V+ 
Sbjct: 219  VPITWYLEDRRLQPGAKYGMEEWGTKRRLTIRDIGVDDDGIYLCEMPDGGRSIAEVAVKG 278

Query: 1283 -VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
             ++   P+ VD      +  G +    V+ +   + +  W  +   +++   T      +
Sbjct: 279  TILRKLPRKVD------VLEGENAAYCVEVEK-EEMDIHWYKDGVELRETHQTIIKSFGR 331

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN--- 1398
            +  L        D+GI    +  +   + + +      +  PP  P  ++I++   N   
Sbjct: 332  THILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSA---RHCPPSCPVGVQINTERANAAL 388

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDT--TEWISVKNITKTQTSIQ----NLKTNSSYRFR 1452
            + W   +++  +    YV+E QE+ T   EW+     T + TS++    ++   + YRFR
Sbjct: 389  LSWVPAQDSRRNPPSGYVLERQEVGTGSQEWLQCLT-TDSATSVEILGDSVPCEADYRFR 447

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSP 1482
              +VN+   S+  E      ++   +IQ+P
Sbjct: 448  ICSVNKYGKSNNVEFPRAVHLVPVARIQAP 477



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 25/81 (30%), Positives = 39/81 (48%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G   +F C V G P+P+I W +   +I   + + +Y D +   TL +     +D G + 
Sbjct: 109 EGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQKDNGVYV 168

Query: 583 CVAKNAAGFASSTTELIVEAP 603
           C A N AG   S   L V+ P
Sbjct: 169 CAASNTAGQTLSAVHLSVKEP 189



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 70/284 (24%), Positives = 109/284 (38%), Gaps = 24/284 (8%)

Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
           S  F + + D     L I +    D G +TC A+N  G A +   L+V+A    H  E  
Sbjct: 7   STHFSVGFQDGGWFQLKIFKTRAPDGGVYTCKARNDFGEALAGAVLLVDAG-PGHEEEGN 65

Query: 613 VXXXXXXXXXXXXADILEG--IPP-------TFSKKPKAQYVDEGSDILLECRLVAIPEP 663
                             G  +P        T S K K   V EG      C +   P+P
Sbjct: 66  RNGYTNCHWKTHQGKPRGGRQMPSRLREDTVTKSTKVKMFAVTEGKHAKFRCFVTGKPKP 125

Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723
           +I W   G  I+        +  D   Y + LK+   K+   G Y   A N  G+    +
Sbjct: 126 EIIWRKDGRLILSGRR--YLLYEDREGYFT-LKVLYCKQKDNGVYVCAASNTAGQTLSAV 182

Query: 724 VLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALP 779
            L +    KEPP +  +PL  + V + +  +L  +V  +  P ITW   ++   P     
Sbjct: 183 HLSV----KEPPVRFKQPLIDLEVWERDLAVLECEVPEDSVP-ITWYLEDRRLQPGAKYG 237

Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAETSAVITV 822
            +  G    +TI +   V D+G+Y  +  +    IAE +   T+
Sbjct: 238 MEEWGTKRRLTI-RDIGVDDDGIYLCEMPDGGRSIAEVAVKGTI 280



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P PE+IW K+G  + + + Y +   +E    +++   K+  +  Y   ASNTAG +
Sbjct: 119  VTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQKDNGVYVCAASNTAGQT 178

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLD 1692
               V L V + P + + P+I  E+  R+   +E + P D
Sbjct: 179  LSAVHLSVKEPPVRFKQPLIDLEVWERDLAVLECEVPED 217



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%)

Query: 513  VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            V+ L  K   + S V  +C V   PR  I W++   +I PS+ F++   +     L+I++
Sbjct: 1290 VKPLEDKTAFEMSRVILDCTVSN-PRCSIRWYKGCTVILPSERFEI-CSEGGYRKLIIQQ 1347

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
            V  +DAGT++       G  S + +L VEA +
Sbjct: 1348 VALDDAGTYSV----QVGEYSCSAKLTVEAQI 1375



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++ WYK+G +L    +  I +  +T ++         S   T     +  +S + V    
Sbjct: 308  DIHWYKDGVELRETHQTIIKSFGRTHILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSAR 367

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVADVD 1720
            +  PS P G  I  E +  ++ + W P  D      + Y +E+ E    +  W++    D
Sbjct: 368  HCPPSCPVGVQINTERANAAL-LSWVPAQDSRRNPPSGYVLERQEVGTGSQEWLQCLTTD 426

Query: 1721 RDVETYCI-QKLNENCEYMFRVIAQNPVGFSEALE 1754
                   +   +    +Y FR+ + N  G S  +E
Sbjct: 427  SATSVEILGDSVPCEADYRFRICSVNKYGKSNNVE 461


>UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin
            CG33484-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
            to zormin CG33484-PA - Apis mellifera
          Length = 3593

 Score =  168 bits (408), Expect = 2e-39
 Identities = 182/708 (25%), Positives = 288/708 (40%), Gaps = 70/708 (9%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            S+ + + P     L+     +G +V+ +C + G P P++ W+     +K S DFQ+ +  
Sbjct: 2039 SDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQG 2098

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
            D   +LVI E F +DAG +  VA N+ G ASS   L V        + +TV         
Sbjct: 2099 DK-CSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTV--------TPVTVSEKLDRART 2149

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                  + G PP F K P    V EG   + EC +V  P+P++ W     E+  +E I +
Sbjct: 2150 EIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILI 2209

Query: 683  AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLK-----------IKT 729
              + D     S+LKI++     +G Y V A N  GEA     +V++           +K 
Sbjct: 2210 QRKED---GTSILKISSAIPEDKGNYVVKAFNEHGEAKAFARLVIRSLGDFRRKEEFVKM 2266

Query: 730  GEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT 786
             EK   P   E  +   V +G S      VVG P P I W  N++PV  K       GD 
Sbjct: 2267 EEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKPSPKIQWLFNDRPVHGKDFLVSVSGDR 2326

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
              +TI +       G  +  AEN+ G A  SA + +   + E               V++
Sbjct: 2327 QVLTIPETGST-HAGTISCVAENAAGKAICSARLEIGGRSVEE--------------VRK 2371

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
             G  ++V  V R+P   +    ++E    SE      +GE    V+T +   I     + 
Sbjct: 2372 VGEKRVVDLVERSPADEMHAASSSEKHFSSE----KSEGEGESQVLTKMSQTIT----ES 2423

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKE 966
              ++   K  + +  T      T  K  Q+        TV    Q+S            +
Sbjct: 2424 TTTHKTTKKEYISSTT----SSTLSKPGQEPTSVSVKTTVHSTEQSSSENGAPPVVQSYK 2479

Query: 967  ISGMDHREIIQE--GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
            +   +H +IIQ+  G             + G+ +  VK  + S     K T P F+  L 
Sbjct: 2480 VE--EHEKIIQDQPGEIRQEKTVVVSQDEEGIKQRDVKAAQISKP-TRKSTAPRFVSPLT 2536

Query: 1025 DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
               V +    ILE  I+      + W ++G+ +K K          H+R L ++  +V D
Sbjct: 2537 GMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVR-LELKKVNVKD 2595

Query: 1084 EGEYSCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT-KGDAL 1136
             G Y+C   +E    S TA++ V +   PP    RLQ Q V +G +   E+E+T   +  
Sbjct: 2596 AGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPT 2655

Query: 1137 VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            V WFKD   I +    +++   G    L I   +   AG+Y     N+
Sbjct: 2656 VTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNA 2703



 Score =  147 bits (356), Expect = 3e-33
 Identities = 134/492 (27%), Positives = 205/492 (41%), Gaps = 51/492 (10%)

Query: 473  YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
            +L D+  YT     KL +      +  +P +E  S  P FV  L       G  V+ EC+
Sbjct: 1898 FLEDKATYTCKATNKLGQASTSAFLDVEP-AEFTSEKPYFVTPLSNAMGRAGQRVKLECE 1956

Query: 533  VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
             +G P P +TW+     ++ S + ++  D    + LVI E F +DAG +T VAKN AG A
Sbjct: 1957 AKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTS-LVISEAFAKDAGCYTVVAKNEAGEA 2015

Query: 593  SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652
            + T  + V+  L    S+                  +E + P      K   V EG  + 
Sbjct: 2016 TVTCNVSVKGRLPHETSD-----------SEFACSDMEPVVPKIQMPLKDLKVQEGLSVR 2064

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L+C +V  PEP++ W    + +    +  +  + D    CS L I        G Y VVA
Sbjct: 2065 LDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQGDK---CS-LVIHEAFLDDAGVYKVVA 2120

Query: 713  VNREGEASLPIVL---KIKTGEK---------------EPPQVIEPLKSMIVRQGESVIL 754
            +N  GEAS    L    +   EK                PP+ ++     +V +GE+ I 
Sbjct: 2121 INSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIF 2180

Query: 755  SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
               VVG P+P + W  ++  V   + +  +   D  SI  +     +D+G Y +KA N  
Sbjct: 2181 ECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIPEDKGNYVVKAFNEH 2240

Query: 812  GIAETSAVITV---------EE--PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            G A+  A + +         EE    EE    P F  RF++  V E  + K    V   P
Sbjct: 2241 GEAKAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKP 2300

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
             P I W  N+  +   + +  +  G+   L I    S   +G   CVA N+AGK+   AR
Sbjct: 2301 SPKIQWLFNDRPVHGKDFLV-SVSGDRQVLTIPETGS-THAGTISCVAENAAGKAICSAR 2358

Query: 921  VTIDVEKVTFVK 932
            + I    V  V+
Sbjct: 2359 LEIGGRSVEEVR 2370



 Score =  138 bits (335), Expect = 1e-30
 Identities = 171/659 (25%), Positives = 284/659 (43%), Gaps = 81/659 (12%)

Query: 306  SIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSY-EDIVESK--KDENEII 362
            ++++  I ++ +KE  K++K V  PP      +TE  +   SY +++V S   K E  I+
Sbjct: 1633 TLEKATIEAKRLKEERKIQK-VSAPPLFSVSAQTEKIETDESYVKEMVTSATIKKEIHIL 1691

Query: 363  QEKQTLEELP-KEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGD 421
            Q+ +  + +P +E  P++  IT  + + +K  E + + ++      F I      V+ G+
Sbjct: 1692 QKTEIEKRVPSREPSPQKKIIT--EETREKSVERMHKESVPPLAPEFTIPLHDATVQEGE 1749

Query: 422  TVFAVYSYVAE-TDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNY 480
                  + + + T E I   +G  + IL+  +    Y+    T     +   +  D   Y
Sbjct: 1750 KFTFQCNLIGQPTPEVIWYKDG--ISILNNPDYLTTYIHGICTLT---IEETFAEDSAKY 1804

Query: 481  TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539
            T               +  K T+ EEQ  +P+FV++L      + S+ Q  C V+G P P
Sbjct: 1805 TCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLP 1864

Query: 540  QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
             + WF+    I  S D+ + Y++   A L   EVF ED  T+TC A N  G AS++  L 
Sbjct: 1865 TVQWFKNDVNIDNSPDYVITYNNGE-AVLKFEEVFLEDKATYTCKATNKLGQASTSAFLD 1923

Query: 600  VEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA 659
            VE   ++  SE                     + P  +   +A     G  + LEC    
Sbjct: 1924 VEP--AEFTSEKPYF-----------------VTPLSNAMGRA-----GQRVKLECEAKG 1959

Query: 660  IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
             P P + W   G  +  +E++++ I+ D      V+     K    G YTVVA N  GEA
Sbjct: 1960 NPMPALTWYHDGRPV--EESMNLKIQMDGGRTSLVISEAFAK--DAGCYTVVAKNEAGEA 2015

Query: 720  SLPIVLKIK-------------TGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            ++   + +K               + EP  P++  PLK + V++G SV L   +VG P P
Sbjct: 2016 TVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEP 2075

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             + W  +++PVK          GD  S+ ++    + D GVY + A NS G A +   +T
Sbjct: 2076 EVIWYHDDQPVKESADFQLLFQGDKCSL-VIHEAFLDDAGVYKVVAINSGGEASSQCTLT 2134

Query: 822  VEEPT------------EEN---AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            V   T            EE      PP F+    +  V E  T      V   P P + W
Sbjct: 2135 VTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKW 2194

Query: 867  YRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + ++  ++ +E   I +  DG +I L I++   E D G+Y   A N  G++   AR+ I
Sbjct: 2195 FSDSGEVTENERILIQRKEDGTSI-LKISSAIPE-DKGNYVVKAFNEHGEAKAFARLVI 2251



 Score =  126 bits (304), Expect = 7e-27
 Identities = 111/433 (25%), Positives = 186/433 (42%), Gaps = 37/433 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P F+       V EG     +C L+  P P++ W   G  I+ + +    + + +H  
Sbjct: 1732 LAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDY---LTTYIHGI 1788

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEP--PQVIEPLKSMIVR 747
            C+ L I          YT  A N  G A     L +K    E++P  P  ++ L + +  
Sbjct: 1789 CT-LTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
            +  S  L+  V GNP PT+ W KN+  +   P       +   +LK ++V  +D+  YT 
Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            KA N  G A TSA + VE P E  +E P F+        +    +KL      NP+P++T
Sbjct: 1908 KATNKLGQASTSAFLDVE-PAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALT 1966

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-- 923
            WY +   +  S  +    DG    LVI+   ++ D+G Y  VA N AG+++    V++  
Sbjct: 1967 WYHDGRPVEESMNLKIQMDGGRTSLVISEAFAK-DAGCYTVVAKNEAGEATVTCNVSVKG 2025

Query: 924  --------------DVEKVT-FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKE 966
                          D+E V   ++   K  + +EG +V L+C        +  WYH+ + 
Sbjct: 2026 RLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQP 2085

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETS---TMLVVKETIPEFIR 1021
            +      +++ +G             D GV K +  +   E S   T+ V   T+ E + 
Sbjct: 2086 VKESADFQLLFQGDKCSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLD 2145

Query: 1022 KLQDFEVKEKDVA 1034
            + +  E++E  VA
Sbjct: 2146 RART-EIEETFVA 2157



 Score =  101 bits (241), Expect = 3e-19
 Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 10/199 (5%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F        VD+G+DI+LE  +   P+P I+W   G+E+   + I++    + H+   
Sbjct: 2529 PRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHN-HVRLE 2587

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            + K+ NVK    G YT  A N  G AS    L +K     PP     L++ +V++GE V 
Sbjct: 2588 LKKV-NVK--DAGRYTCTASNEVGSASSTADLVVKK-TIFPPVFGRRLQAQVVKRGERVN 2643

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            +  ++ G P PT+TW K++ P+K  P     K  G+ + + I K +K    G Y ++A N
Sbjct: 2644 MEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKA-HAGKYMVRATN 2702

Query: 810  SEGIAETSAVITVEEPTEE 828
            + G A++ A   V EPT +
Sbjct: 2703 AGGEAQSIADFAVFEPTPD 2721



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 66/243 (27%), Positives = 109/243 (44%), Gaps = 8/243 (3%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDT 786
            T +   P+ + PL  MIV QG  +IL   + G P+P+I+W KN + +K     T +    
Sbjct: 2523 TRKSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHN 2582

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
            H    LK   VKD G YT  A N  G A ++A + V    ++   PP+F  R Q   VK 
Sbjct: 2583 HVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVV----KKTIFPPVFGRRLQAQVVKR 2638

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
               + +   +T  P P++TW++++  I       +     N  ++I +   +  +G Y  
Sbjct: 2639 GERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMV 2698

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKS--YETEEGKTVILECQTSHTVSTKWYHNK 964
             A+N+ G++   A   +       +  + K+  YE  + K V  E   +   S K     
Sbjct: 2699 RATNAGGEAQSIADFAVFEPTPDTMTEVHKTVIYENVQDKKVTQETIYTTDQSHKKLETT 2758

Query: 965  KEI 967
            K+I
Sbjct: 2759 KKI 2761



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 73/296 (24%), Positives = 124/296 (41%), Gaps = 19/296 (6%)

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            +V  L PE    L +  V +G K TF+  L  +    V W+KDG  I  +     T    
Sbjct: 1728 SVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHG 1787

Query: 1160 KQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFI------LVP 1209
               L I +   +D+ +Y+C+     G+++ +A LTV+E +       P F+      +  
Sbjct: 1788 ICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847

Query: 1210 ANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
             N+   L   +    L  V W+K    I+++  + +  +  +  L   +   +D+  YTC
Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907

Query: 1269 V----LLDAKSTTKLKVEVVEFP---PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
                 L  A ++  L VE  EF    P  V        + G  V L  + +  P P   W
Sbjct: 1908 KATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALTW 1967

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              + + +++  + K  +D    SL I +    DAG Y +  +N  G A V  NV++
Sbjct: 1968 YHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSV 2023



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 61/274 (22%), Positives = 106/274 (38%), Gaps = 11/274 (4%)

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +E  E    E ++   I K    +Q  +       R  +  +  I++ +      ++ KE
Sbjct: 1668 IETDESYVKEMVTSATIKKEIHILQKTEIEKRVPSREPSPQKKIITEETREKSVERMHKE 1727

Query: 1477 TKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR 1532
            +    +P    PL + T +  E     C   G P P+V WY+DG  +        TY + 
Sbjct: 1728 SVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHG 1787

Query: 1533 X-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C AFN  G  ETS  + +++       +  +  K  +    L
Sbjct: 1788 ICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847

Query: 1592 ------VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
                  +   ++G P P V W+KN   ++N  +Y IT     +V++ +E+     + YT 
Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            +A+N  G +S    L V       E P  +  +S
Sbjct: 1908 KATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLS 1941



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 60/259 (23%), Positives = 107/259 (41%), Gaps = 11/259 (4%)

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TY-ENRX 1533
            K  +P    PL  +  +   DI L  I  G PQP ++W ++G++LKT      TY  N  
Sbjct: 2525 KSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHV 2584

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592
                          Y C A N+ G   ++  + +++     +    ++ Q  K G+   +
Sbjct: 2585 RLELKKVNVKDAGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNM 2644

Query: 1593 TAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
               I G P P V W+K+   + E   E  I  +    ++ I + +++H+ KY + A+N  
Sbjct: 2645 EVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAG 2704

Query: 1652 GTSSVEVTLKVY----DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL-TKYAIEKH 1706
            G +       V+    D  ++    VI   +  + VT E     D    +L T   I   
Sbjct: 2705 GEAQSIADFAVFEPTPDTMTEVHKTVIYENVQDKKVTQETIYTTDQSHKKLETTKKILPP 2764

Query: 1707 EPDNNRWIKVADVDRDVET 1725
             P  ++++K    + D E+
Sbjct: 2765 SPSPSKFVKGEFRESDYES 2783



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 3/117 (2%)

Query: 485  QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
            ++ + ++  K     KPT   +S AP FV  L       G+ +  E  ++G+P+P I+W 
Sbjct: 2506 EEGIKQRDVKAAQISKPT--RKSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWS 2563

Query: 545  RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +    +K      + Y  ++V  L +++V  +DAG +TC A N  G ASST +L+V+
Sbjct: 2564 KNGQELKTKDGITITYAHNHVR-LELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 3/102 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+++     + G P PEVIWYK+G  + N+ +Y  T       + I+E     S+KYT +
Sbjct: 1748 GEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHGICTLTIEETFAEDSAKYTCK 1807

Query: 1647 ASNTAGTSSVEVTLKVYD--KPSKPEGPVIMREISRESVTIE 1686
            A N AG++    TL V +     +P  PV ++E+   SV +E
Sbjct: 1808 AFNIAGSAETSATLTVKETAPEEQPSSPVFVKEL-MASVALE 1848



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 53/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%)

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            +I+      S ++   A N    ++ S T    +   E +  SP   K L       N  
Sbjct: 1792 TIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSS 1851

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYEN-RXXXXXXXXXXXXXXXYKCIAFN 1554
             +L C   G P P V W+++   +  +     TY N                 Y C A N
Sbjct: 1852 HQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATN 1911

Query: 1555 DHGEVETSCVVGIQ------QKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
              G+  TS  + ++      +KP  V  +SN       + G    +    +G P P + W
Sbjct: 1912 KLGQASTSAFLDVEPAEFTSEKPYFVTPLSNA----MGRAGQRVKLECEAKGNPMPALTW 1967

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            Y +G  +E      I      + + I E     +  YT+ A N AG ++V   + V
Sbjct: 1968 YHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSV 2023



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 94/495 (18%), Positives = 180/495 (36%), Gaps = 53/495 (10%)

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL------DA 1273
            I   T +V WYK    I +   +         TL I +   +D  +YTC         + 
Sbjct: 1758 IGQPTPEVIWYKDGISILNNPDYLTTYIHGICTLTIEETFAEDSAKYTCKAFNIAGSAET 1817

Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIK---RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
             +T  +K    E  P    + +E         S   L    +  P P  +W  N   I  
Sbjct: 1818 SATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKNDVNIDN 1877

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
                  + ++  A L  ++V   D   Y  +  N  G A     + +        KP  +
Sbjct: 1878 SPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLGQASTSAFLDVEPAEFTSEKPYFV 1937

Query: 1391 EIDSSSINICWD----EPENTGNST-IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLK 1444
               S+++         E E  GN    + +  + + ++ +  + ++ +  +T   I    
Sbjct: 1938 TPLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTSLVISEAF 1997

Query: 1445 TNSSYRFRAYAVNEVDISDAS-----------ETTEYYKVIKETKIQSPTVEKPLKNITT 1493
               +  +   A NE   +  +           ET++      + +   P ++ PLK++  
Sbjct: 1998 AKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKV 2057

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXY 1548
            +    + L C+  G P+P+V WY D + +K + A ++     ++               Y
Sbjct: 2058 QEGLSVRLDCVIVGQPEPEVIWYHDDQPVKES-ADFQLLFQGDKCSLVIHEAFLDDAGVY 2116

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPV---ITISNEDIKQKHKVGD---------EWLV---- 1592
            K +A N  GE  + C + +    V   +  +  +I++    G          + LV    
Sbjct: 2117 KVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGE 2176

Query: 1593 TAVIE----GIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEA 1647
            TA+ E    G P PE+ W+ +  ++  ++   I  KE  TS+++I          Y ++A
Sbjct: 2177 TAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIPEDKGNYVVKA 2236

Query: 1648 SNTAGTSSVEVTLKV 1662
             N  G +     L +
Sbjct: 2237 FNEHGEAKAFARLVI 2251



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 29/102 (28%), Positives = 43/102 (42%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F  +L+ +    G  V  E ++ G P P +TWF+    IK            N   L+
Sbjct: 2625 PVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLI 2684

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
            I +     AG +   A NA G A S  +  V  P  D  +E+
Sbjct: 2685 IDKAEKAHAGKYMVRATNAGGEAQSIADFAVFEPTPDTMTEV 2726



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F ++ +AQ V  G  + +E  +   PEP + W FK +  + +    + I+   +  C
Sbjct: 2624 PPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTW-FKDDVPIKERPPELRIKQQGN--C 2680

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
             +L I   +K   G Y V A N  GEA    +      E  P  + E  K++I
Sbjct: 2681 YMLIIDKAEKAHAGKYMVRATNAGGEAQ--SIADFAVFEPTPDTMTEVHKTVI 2731



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 6/162 (3%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE 1282
            ++W K    ++  +  T+        L ++K    D   YTC   +    A ST  L V+
Sbjct: 2560 ISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSK 1341
               FPP      +   +KRG  V + V+    P+P   W  +   IK +    +      
Sbjct: 2620 KTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGN 2679

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
               L I K E   AG Y +R  N  G A    +  + + P+P
Sbjct: 2680 CYMLIIDKAEKAHAGKYMVRATNAGGEAQSIADFAVFE-PTP 2720



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 19/209 (9%)

Query: 1000 IVKDQETSTMLVVKETIPE-------FIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            I    ETS  L VKET PE       F+++L      E     L   +       V    
Sbjct: 1811 IAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFK 1870

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEVTVVEL- 1105
             ++       Y          L      + D+  Y+C   ++      S   +V   E  
Sbjct: 1871 NDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLGQASTSAFLDVEPAEFT 1930

Query: 1106 --PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
               P  +T L N     G +   E E  KG+ +  + W+ DG  ++ S ++++ +DG + 
Sbjct: 1931 SEKPYFVTPLSNAMGRAGQRVKLECE-AKGNPMPALTWYHDGRPVEESMNLKIQMDGGRT 1989

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
             L I +    DAG Y+    N    A +T
Sbjct: 1990 SLVISEAFAKDAGCYTVVAKNEAGEATVT 2018



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575
            G T +FEC V+  P+P I W +   II+ S  ++++Y  + V  L I   FP
Sbjct: 3351 GQTARFECIVQAEPQPNILWSKDGRIIENSSCYEIHY-RNGVCRLTIVRAFP 3401



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 14/112 (12%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
            + W K+G E++  + I +T      +L++   ++ DAG Y+C    EVG++  TA L V+
Sbjct: 2560 ISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619

Query: 1193 E---PSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIED 1238
            +   P + F  RL +  +V       + VEI   P+ T  VTW+K    I++
Sbjct: 2620 KTIFPPV-FGRRL-QAQVVKRGERVNMEVEITGTPEPT--VTWFKDDVPIKE 2667



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 23/86 (26%), Positives = 35/86 (40%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + +G+D+ L      FPQP+  W  N + +K       +       L +KKV   DAG Y
Sbjct: 2540 VDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRY 2599

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384
                 N  G A    ++ +     PP
Sbjct: 2600 TCTASNEVGSASSTADLVVKKTIFPP 2625



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 6/105 (5%)

Query: 1420 QEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
            QE+ T + I++       +  ++ +    + R+   A NEV    AS T +   V+K+T 
Sbjct: 2567 QELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEV--GSASSTADL--VVKKT- 2621

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            I  P   + L+    +  E + +     G P+P VTW++D   +K
Sbjct: 2622 IFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIK 2666


>UniRef50_Q4RE91 Cluster: Chromosome undetermined SCAF15134, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF15134, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1216

 Score =  167 bits (406), Expect = 3e-39
 Identities = 271/1166 (23%), Positives = 469/1166 (40%), Gaps = 88/1166 (7%)

Query: 154  EKS--DLFDSQEDESKP-DVSQPPQNIIEEAKS--EPKLIEESEQPIAKTSEIDNEVPEK 208
            EKS  D  + Q    KP D    P++ +EEAK+  E K I   EQ +         VP K
Sbjct: 56   EKSPPDEKEPQAKVPKPADKKISPESALEEAKAPAEIKKIPTQEQEMESVRLKPISVPSK 115

Query: 209  I-NVPDDKETSQTPTSFNKRSKL-TPIKIER-KEMEVSTPQHAETVDGPQFXXXXXXXXX 265
            +   P+ K   +  T      +L + I +E+ KE E    Q+   +              
Sbjct: 116  VVGEPEKKPLEKKDTKAVDDKQLHSRISVEKPKEQEPGLKQNKAEIPEAAEKKPEKTPEV 175

Query: 266  XXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKK 325
                 E  +  LP    K       + P +  K +IS +   K+  +L+  +K+  KV+ 
Sbjct: 176  KTVREEEKVHALPPSIEKLEKTPEEAKPLQLKKGVISKLKVEKEEVVLTP-VKQLKKVQL 234

Query: 326  QVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEII-----QEKQTLEELPKEDVPEQY 380
            +    PK   VEK +  QP+ S E I    K +   I     +  + ++++ K+ +PE+ 
Sbjct: 235  KKTPSPK---VEKPKEAQPI-SVEKIPGRDKLKKVPITDTPKESAEAMKKVLKKSLPEEE 290

Query: 381  TITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAV-YSYVAETDEAINL 439
             I P     +K+D+  +++ I K ++P  +    +  +  + VF   +    E  +    
Sbjct: 291  KIAP----PEKLDK--EKIPIVKEVSPGAVQMKKIATQPEEEVFEEEFGVEEEAVQEEGE 344

Query: 440  VEGERLYILDT-SNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVF 498
            V G  L   ++  ++DW    +    E   V  +     +   +   + L       P  
Sbjct: 345  VWGWELVPQESYGSEDWEGEGEDGALEVPGVTRRARQTPSP-GEGRGRGLKPGGRGTPPP 403

Query: 499  EKPTSEEQSMA-PI-FVEKLRP---KHTPD-GSTVQFECQVEGYPRPQIT-WFRQTAIIK 551
            E+P    +  A P+ F++KL+    K     GS+  FEC+V   P   +T W +    ++
Sbjct: 404  EEPFGGFKLKAVPLKFIKKLQDIVLKEAESIGSSAVFECEVS--PSTAVTSWMKDGGNLR 461

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-------APL 604
             S   + +  D     L I +V   D G +TCVAKNA    S   +LIVE         L
Sbjct: 462  ESPKHK-FTSDGKDRKLNIIDVQLSDTGEYTCVAKNAGKEISCMAKLIVEELPVKWIKEL 520

Query: 605  SDHGSEMTVXXXXXXXXXXXXADIL---EG-IPPTFSKKPKAQYVDEGSDILLECRLVAI 660
             +  S +               D++   +G +    + K +   +   +   LE     I
Sbjct: 521  EEETSALKGQPLYVTCELNKERDVIWKKDGEVLKKKAGKIQINVIXTTARFELELSHENI 580

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P   + W     +I P   +   ++   H    VL+I  V    + T  + A  +     
Sbjct: 581  P---VTWYKNDAKIHPSRTVLTHVDGKRH----VLEIKEVT--LDDTCQIKAEAK----G 627

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKA 777
            +P +  +   E +    ++ L+     + + V+L  ++  N    + W  N    +P K 
Sbjct: 628  IPSMANLTVIEGDAYFTVK-LQDYTAVEKDKVVLDCEL--NKDVDVMWYHNEAEIRPSKM 684

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
            +  K+DG   S+ I +    KDEG Y        G  +TSA + ++      A     + 
Sbjct: 685  VSIKADGKRRSLIISRVTD-KDEGQYVCDC----GTDKTSATLHIK------ARHIKVLR 733

Query: 838  RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
                  V E  T +    ++ + V    W  N E++SPS  I    DG    LV+ N   
Sbjct: 734  PMYGAEVFEGETARFEVELSEDDVHG-QWSLNGELLSPSSDIEIVEDGPKHTLVLYNCRV 792

Query: 898  EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957
               +G+    A+N+  K S  A + +    ++F+  L   Y  E+ +    E + S    
Sbjct: 793  P-QTGEVVFTAANA--KCS--ANLKVKEIPISFITPLADVYVYEKDE-ARFELEISREPK 846

Query: 958  T-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
              +W    +E+   D  E++ EG+            D        +D+ TS  L ++   
Sbjct: 847  NFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQGIR 906

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             +FI+ ++D  VKE++ A    E++ E   VVW ++   + P K  +  E  G +  L  
Sbjct: 907  LDFIKPIKDVTVKERETAEFSTELSHEKIPVVWYKNEVRLHPSKVVHITED-GKVHMLAF 965

Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136
            +  +V D          +S  A +TV+E       +LQN    + ++A    EL+K  A 
Sbjct: 966  KELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKATAD 1025

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
            V+WFKDG E+  S +I +  DGKK+ L I       AG Y+C     K T+ L +EE  I
Sbjct: 1026 VKWFKDGEEVFPSKNILIKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIEEREI 1085

Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256
                 L    +    T  + T EI +  +  TW  K   +  +    +  +  +  LI+ 
Sbjct: 1086 KVVRPLYSVEVTETETAKFET-EISERDIHATWKLKGETLHPSADVEIKEEGARHMLILF 1144

Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             C +D       +  +AKS+ +L+V+
Sbjct: 1145 NCKKDMAGGVDFLAANAKSSAQLRVK 1170



 Score =  165 bits (401), Expect = 1e-38
 Identities = 157/664 (23%), Positives = 282/664 (42%), Gaps = 53/664 (7%)

Query: 734  PPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTIT-WCKNNKPVKALPTK---SDGDTH 787
            P + I+ L+ +++++ ES+  SA  +   +P   +T W K+   ++  P     SDG   
Sbjct: 416  PLKFIKKLQDIVLKEAESIGSSAVFECEVSPSTAVTSWMKDGGNLRESPKHKFTSDGKDR 475

Query: 788  SITILKPKKVKDEGVYTLKAENS--------EGIAETSAVITVEEPTEENAE---PPLFI 836
             + I+  + + D G YT  A+N+        + I E   V  ++E  EE +     PL++
Sbjct: 476  KLNIIDVQ-LSDTGEYTCVAKNAGKEISCMAKLIVEELPVKWIKELEEETSALKGQPLYV 534

Query: 837  ----NRFQEITVKEKGTI--KLVARVTRNPVPS--------------ITWYRNNEIISPS 876
                N+ +++  K+ G +  K   ++  N + +              +TWY+N+  I PS
Sbjct: 535  TCELNKERDVIWKKDGEVLKKKAGKIQINVIXTTARFELELSHENIPVTWYKNDAKIHPS 594

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
             T+  + DG+   L I     E+   D   + + + G  S  A +T+      F   LQ 
Sbjct: 595  RTVLTHVDGKRHVLEI----KEVTLDDTCQIKAEAKGIPSM-ANLTVIEGDAYFTVKLQ- 648

Query: 937  SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
             Y   E   V+L+C+ +  V   WYHN+ EI       I  +G+            D G 
Sbjct: 649  DYTAVEKDKVVLDCELNKDVDVMWYHNEAEIRPSKMVSIKADGKRRSLIISRVTDKDEGQ 708

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
              C     +TS  L +K    + +R +   EV E + A  EVE++ +     W  +GE++
Sbjct: 709  YVCDCGTDKTSATLHIKARHIKVLRPMYGAEVFEGETARFEVELSEDDVHGQWSLNGELL 768

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
             P  +  +  + G    L + N  V   GE      +  C+A + V E+P   IT L + 
Sbjct: 769  SPSSD-IEIVEDGPKHTLVLYNCRVPQTGEVVFTAANAKCSANLKVKEIPISFITPLADV 827

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
             V + ++A FE+E+++     RW K   E+   +  +L ++GKK  L I     +D  +Y
Sbjct: 828  YVYEKDEARFELEISREPKNFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKY 887

Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
            + E  + + +  L ++   ++F   + + + V     A  + E+  E + V WYK +  +
Sbjct: 888  TFEAEDKRTSGKLFIQGIRLDFIKPIKD-VTVKERETAEFSTELSHEKIPVVWYKNEVRL 946

Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFPPKIVDYE 1294
              ++   +  D K   L  ++ T DD        +   S   L V    V F  K+ +Y 
Sbjct: 947  HPSKVVHITEDGKVHMLAFKELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYT 1006

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
               +     D  +L    +    + +W  + + +   K+     D K   L IKK   + 
Sbjct: 1007 AVEK-----DEAILSCELSKATADVKWFKDGEEVFPSKNILIKSDGKKRMLVIKKAAKSS 1061

Query: 1355 AGIY 1358
            AG Y
Sbjct: 1062 AGTY 1065



 Score =  141 bits (341), Expect = 2e-31
 Identities = 138/573 (24%), Positives = 237/573 (41%), Gaps = 24/573 (4%)

Query: 945  TVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
            T   E + SH  +   WY N  +I          +G+            D   IK   K 
Sbjct: 568  TARFELELSHENIPVTWYKNDAKIHPSRTVLTHVDGKRHVLEIKEVTLDDTCQIKAEAKG 627

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
              +   L V E    F  KLQD+   EKD  +L+ E+N +  DV+W  +   I+P K   
Sbjct: 628  IPSMANLTVIEGDAYFTVKLQDYTAVEKDKVVLDCELNKDV-DVMWYHNEAEIRPSK-MV 685

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
              +  G  R L I   +  DEG+Y C    +  +A + +     +++  +   +V +G  
Sbjct: 686  SIKADGKRRSLIISRVTDKDEGQYVCDCGTDKTSATLHIKARHIKVLRPMYGAEVFEGET 745

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            A FE+EL++ D   +W  +G  +  S+ I++  DG K  L +Y+C +   GE      N+
Sbjct: 746  ARFEVELSEDDVHGQWSLNGELLSPSSDIEIVEDGPKHTLVLYNCRVPQTGEVVFTAANA 805

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
            KC+A L V+E  I+F   L + + V    +A   +EI  E  +  W K    + + +KF 
Sbjct: 806  KCSANLKVKEIPISFITPLAD-VYVYEKDEARFELEISREPKNFRWLKGPQELVNDDKFE 864

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKR 1301
            L+ + KK  L+I+    +D+ +YT    D +++ KL ++ +  +F   I D   + R   
Sbjct: 865  LLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQGIRLDFIKPIKDVTVKER--E 922

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
             ++ +  + ++  P     W  N   +   K    + D K   L  K++   D  + K+ 
Sbjct: 923  TAEFSTELSHEKIPV---VWYKNEVRLHPSKVVHITEDGKVHMLAFKELTVDDTSMIKVE 979

Query: 1362 LENNCGHA-------DVEMNVTILDKPSPPGKPNIL--EIDSSSINICW-DEPENTGNST 1411
                   A       DV   V + +  +      IL  E+  ++ ++ W  + E    S 
Sbjct: 980  AMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKATADVKWFKDGEEVFPSK 1039

Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             I    + ++       + K+   T T S    KT S        +  V    + E TE 
Sbjct: 1040 NILIKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIEEREIKVVRPLYSVEVTET 1099

Query: 1471 YKVIKETKIQSPTVEK--PLKNITTEPNEDIEL 1501
                 ET+I    +     LK  T  P+ D+E+
Sbjct: 1100 ETAKFETEISERDIHATWKLKGETLHPSADVEI 1132



 Score =  141 bits (341), Expect = 2e-31
 Identities = 145/614 (23%), Positives = 259/614 (42%), Gaps = 40/614 (6%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++EG    F+ K +     E   ++L+C L    + D+ W     EI P + +S+  +  
Sbjct: 636  VIEG-DAYFTVKLQDYTAVEKDKVVLDCELNK--DVDVMWYHNEAEIRPSKMVSIKADGK 692

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                   L I+ V    EG Y       +  A+L I       +    +V+ P+    V 
Sbjct: 693  RRS----LIISRVTDKDEGQYVCDCGTDKTSATLHI-------KARHIKVLRPMYGAEVF 741

Query: 748  QGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +GE+     ++  +      W  N +   P   +    DG  H++ +L   +V   G   
Sbjct: 742  EGETARFEVELSEDDVHG-QWSLNGELLSPSSDIEIVEDGPKHTL-VLYNCRVPQTGEVV 799

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A N    A+ SA + V+E       P  FI    ++ V EK   +    ++R P  + 
Sbjct: 800  FTAAN----AKCSANLKVKEI------PISFITPLADVYVYEKDEARFELEISREP-KNF 848

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W +  + +   +      +G+   L+I +   E D   Y   A +   K + G ++ I 
Sbjct: 849  RWLKGPQELVNDDKFELLVEGKKHILLIKSAKYE-DEAKYTFEAED---KRTSG-KLFIQ 903

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983
              ++ F+K + K    +E +T     + SH  +   WY N+  +       I ++G+   
Sbjct: 904  GIRLDFIKPI-KDVTVKERETAEFSTELSHEKIPVVWYKNEVRLHPSKVVHITEDGKVHM 962

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                     D  +IK     + +  ML V E    F  KLQ++   EKD AIL  E++  
Sbjct: 963  LAFKELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKA 1022

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
            TADV W +DGE + P KN    +  G  R L I+  +    G Y+C    +  T+++ + 
Sbjct: 1023 TADVKWFKDGEEVFPSKNIL-IKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIE 1081

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            E   +++  L + +V +   A FE E+++ D    W   G  +  S  +++  +G +  L
Sbjct: 1082 EREIKVVRPLYSVEVTETETAKFETEISERDIHATWKLKGETLHPSADVEIKEEGARHML 1141

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223
             +++C  D AG       N+K +A L V+   I+    L + + V A   A L+V +  E
Sbjct: 1142 ILFNCKKDMAGGVDFLAANAKSSAQLRVKARIISLMRPLKD-VTVTAGETATLSVSV-YE 1199

Query: 1224 TLDVTWYKKKSVIE 1237
             + V W+ + + +E
Sbjct: 1200 GIAVEWFLEGTKLE 1213



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 8/95 (8%)

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN--TAGTSSVEV 1658
            P    W K   +L ND ++ +  + K  ++ IK  K    +KYT EA +  T+G   ++ 
Sbjct: 845  PKNFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQG 904

Query: 1659 TLKVYDKPSKP------EGPVIMREISRESVTIEW 1687
                + KP K       E      E+S E + + W
Sbjct: 905  IRLDFIKPIKDVTVKERETAEFSTELSHEKIPVVW 939



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
            +D+  K +   E+      E IP   V+WYKN  +L   K  +IT   K  ++  KEL  
Sbjct: 914  KDVTVKERETAEFSTELSHEKIP---VVWYKNEVRLHPSKVVHITEDGKVHMLAFKELTV 970

Query: 1638 SHSSKYTIEA---SNTAGTSSVE------VTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
              +S   +EA   S+ A  + +E      V L+ Y    K E  ++  E+S+ +  ++W
Sbjct: 971  DDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEA-ILSCELSKATADVKW 1028


>UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-PA -
            Drosophila melanogaster (Fruit fly)
          Length = 1427

 Score =  164 bits (398), Expect = 3e-38
 Identities = 113/395 (28%), Positives = 177/395 (44%), Gaps = 17/395 (4%)

Query: 1380 KPSPPGKPNILEI-----DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-- 1432
            +PSPPG+P +  +         +N+ WD P + G S I  Y VE++ + +  W+      
Sbjct: 12   RPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATPTP 71

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNI 1491
            + +    I  L+    Y+FR +A N V  SDASE ++   V ++   I  P     L + 
Sbjct: 72   VDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNAITVPRFIDELVDT 131

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXX- 1547
                +E IE      G P P++ W++DG ++ +++ T    +N                 
Sbjct: 132  NAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGE 191

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIW 1606
             KC A N  G V T   + +Q  P I +            DE L   V + G PPP + W
Sbjct: 192  IKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITW 251

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
               G  +     + ++  EK S+++I  + R    +Y ++A N  G  S    + V  +P
Sbjct: 252  LHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARP 311

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
            + P  P +     + S T+ W  PLDDGG ++  Y +E      N W+K A   R + T 
Sbjct: 312  NPPGTPKLNMSFGK-SATLSWTAPLDDGGCKIGNYIVEYFRVGWNVWLKAA-TTRALST- 368

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVI 1760
             +  L E  EY FRV A+NP G SE + ESE + I
Sbjct: 369  TLHDLIEGSEYKFRVKAENPYGLSEPSGESELLFI 403



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 61/248 (24%), Positives = 103/248 (41%), Gaps = 4/248 (1%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            ++ W+K    I  + +  +++D +   L+I +    D+ E  C   +       K  + V
Sbjct: 152  EINWFKDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGEIKCTATNRAGHVITKARLMV 211

Query: 1285 EFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            + PPKI     YE    ++    + L V     P P   W+   ++I      + S   K
Sbjct: 212  QAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTEK 271

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            ++ L I  V   D G Y ++  N  G       VT+  +P+PPG P +      S  + W
Sbjct: 272  NSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARPNPPGTPKLNMSFGKSATLSW 331

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              P + G   I  Y+VEY  +    W+         T++ +L   S Y+FR  A N   +
Sbjct: 332  TAPLDDGGCKIGNYIVEYFRVGWNVWLKAATTRALSTTLHDLIEGSEYKFRVKAENPYGL 391

Query: 1462 SDASETTE 1469
            S+ S  +E
Sbjct: 392  SEPSGESE 399



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 93/408 (22%), Positives = 153/408 (37%), Gaps = 31/408 (7%)

Query: 1663 YDKPSKPEGPVI----MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
            + +PS P  P++    + E   + V + W  PL DGG  +T Y +E     +  W++   
Sbjct: 10   HQRPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATP 69

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXX 1774
               D    CI  L     Y FR  A+N VG S+A E S+P+ +   + A+ VP       
Sbjct: 70   TPVDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNAITVPRFIDELV 129

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT 1834
                +++E +    F     G  P      EI      ++             + S+   
Sbjct: 130  DTNAVEDERIE---FRVRILGEPP-----PEINWFKDGYEIFSSRRTKIVNDNEASVLVI 181

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTL--TPPS--QPRNFVVSESTSRSVTLKWTEPE 1890
            +Q  +    EI  +    +   IT  + +   PP    PR +           L+     
Sbjct: 182  HQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGV 241

Query: 1891 SNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
            +    P   ++ E + +  G  +    T   S+ +  I+N+  +D   + + A N +G  
Sbjct: 242  AGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLK--IDNVLREDRGEYMVKAWNRLG-- 297

Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
               E  +  L      P+PP  P ++ M        SW  P  DGG  +  Y +    V 
Sbjct: 298  ---EDSTSFLVTVTARPNPPGTP-KLNMSFGKSATLSWTAPLDDGGCKIGNYIVEYFRVG 353

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              +W++        L   + DL E   Y  R+ A N  GLSEP    E
Sbjct: 354  WNVWLKA--ATTRALSTTLHDLIEGSEYKFRVKAENPYGLSEPSGESE 399



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 11/218 (5%)

Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
           +V  +   E S P+ + ++      P+ I+ L      + E +    +++G P P I W 
Sbjct: 97  IVGRSDASELSDPLTVTLQRNAITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWF 156

Query: 770 KNNKPV-KALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
           K+   +  +  TK   D   S+ ++    + DEG     A N  G   T A + V+ P  
Sbjct: 157 KDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGEIKCTATNRAGHVITKARLMVQAP-- 214

Query: 828 ENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
               P + + R  E  + V+    ++L   V   P P+ITW    E+I+P      +   
Sbjct: 215 ----PKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTE 270

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           +N  L I NV  E D G+Y   A N  G+ S    VT+
Sbjct: 271 KNSLLKIDNVLRE-DRGEYMVKAWNRLGEDSTSFLVTV 307



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 13/193 (6%)

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           E   I    R++  P P+I W   G EI       +  +++     SVL I  V    EG
Sbjct: 135 EDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNE----ASVLVIHQVALTDEG 190

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763
                A NR G     ++ K +   + PP++  P      +IV   E + L   V G P 
Sbjct: 191 EIKCTATNRAGH----VITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPP 246

Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVIT 821
           P ITW    + +         +T   ++LK   V  +D G Y +KA N  G   TS ++T
Sbjct: 247 PAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVT 306

Query: 822 VEEPTEENAEPPL 834
           V         P L
Sbjct: 307 VTARPNPPGTPKL 319



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 1/94 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++L   +  +   ++F  ++ G P P+I WF+    I  S+  ++  +D+  + LV
Sbjct: 122 PRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIV-NDNEASVLV 180

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           I +V   D G   C A N AG   +   L+V+AP
Sbjct: 181 IHQVALTDEGEIKCTATNRAGHVITKARLMVQAP 214



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 4/100 (4%)

Query: 1966 PSPP----TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021
            PSPP      P+ +     ++V   W  P  DGG+P+ GY +  R +    W+      V
Sbjct: 13   PSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATPTPV 72

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            +     I  L     Y  R +A N +G S+  E  +P  V
Sbjct: 73   DRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTV 112



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 42/167 (25%), Positives = 67/167 (40%), Gaps = 7/167 (4%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  I  L +    +  +  F +  L +    + WFKDG EI  S   ++  D +   L I
Sbjct: 122  PRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVI 181

Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEI 1220
            +   L D GE  C      G+    A L V+  P I       + ++V A+    L V +
Sbjct: 182  HQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGV 241

Query: 1221 PDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
              +    +TW  +  VI    +F + +  K   L I     +D+ EY
Sbjct: 242  AGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEY 288



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 11/142 (7%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ---YVDEGSDIL-L 653
           +I +  L+D G E+              A ++   PP   + P+      + E  ++L L
Sbjct: 180 VIHQVALTDEG-EIKCTATNRAGHVITKARLMVQAPPKI-RLPRTYEDGLIVEADEVLRL 237

Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
           +  +   P P I WL +GE I P     V+  ++ +   S+LKI NV +   G Y V A 
Sbjct: 238 KVGVAGQPPPAITWLHEGEVIAPGGRFEVS-NTEKN---SLLKIDNVLREDRGEYMVKAW 293

Query: 714 NREGEASLPIVLKIKTGEKEPP 735
           NR GE S   ++ + T    PP
Sbjct: 294 NRLGEDSTSFLVTV-TARPNPP 314



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 44/191 (23%), Positives = 77/191 (40%), Gaps = 11/191 (5%)

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG-EIIKP 1058
            + D  T T+     T+P FI +L D    E +     V I  E   ++ W +DG EI   
Sbjct: 106  LSDPLTVTLQRNAITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSS 165

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEI-ITRLQ 1114
            ++ K   +    +  L I   ++ DEGE  C   + +    T    +V+ PP+I + R  
Sbjct: 166  RRTKIVNDNEASV--LVIHQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTY 223

Query: 1115 NQKVNKGNKATFEIELT---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
               +         +++    +    + W  +G  I      +++   K   LKI +   +
Sbjct: 224  EDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLRE 283

Query: 1172 DAGEYSCEVGN 1182
            D GEY  +  N
Sbjct: 284  DRGEYMVKAWN 294



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
           V G P P ITW  +  +I P   F++   + N + L I  V  ED G +   A N  G  
Sbjct: 241 VAGQPPPAITWLHEGEVIAPGGRFEVSNTEKN-SLLKIDNVLREDRGEYMVKAWNRLGED 299

Query: 593 SSTTELIVEA 602
           S++  + V A
Sbjct: 300 STSFLVTVTA 309


>UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 1509

 Score =  162 bits (394), Expect = 8e-38
 Identities = 225/1049 (21%), Positives = 405/1049 (38%), Gaps = 94/1049 (8%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            +A  F+ +L+     + S V FEC+    P  ++TW + T  IK    +++      +  
Sbjct: 469  LANKFICELKDATADENSDVSFECET-AQPATKVTWLKGTKEIKAGGRYELT-QKGAILI 526

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTE-----LIVEAPLSDHGSEMTVXXXXXXXXX 622
            L ++++   D+  +TC   +    A  T +      ++ +          +         
Sbjct: 527  LKVKDLEKSDSEVYTCDIGSTKTTAKLTVKEHHYNKLIPSSSQPSNPPSCLLDVKTVKNH 586

Query: 623  XXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
                 +++   +P  F ++ K Q V EG  +LL C L + P   + W  KG E + +   
Sbjct: 587  FKYMILVQSPVLPAKFKEQMKNQQVTEGEKVLLSCML-SKPGCQVQWK-KGTECLKNGGR 644

Query: 681  SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
               ++ D       L+I+ +     G Y+    N +  A+L +          P      
Sbjct: 645  YQIMQRDTIFE---LQISELAVEDSGEYSCECGNEKTTANLVV-------SALPVVFKHE 694

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKV 797
            L+S     G++V L+ ++   P   + W K  + + +      K DG    + I    K+
Sbjct: 695  LQSQECEGGDTVTLNCEL-SKPGVPVVWKKGTQVLHSGEKYLIKQDGANVELKIAD-LKL 752

Query: 798  KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            +D G YT       G  +T+A I ++           F     ++  +E  ++ L   ++
Sbjct: 753  EDGGQYTCLC----GDKKTTANIKIKALN--------FKRELHDMKCQEADSVTLQCELS 800

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
            +  VP + W +  ++I   E       G   EL I ++  E D+G Y C      G +  
Sbjct: 801  KPGVP-VVWRKGTQVIHSGEKYHIKQVGSTFELKINDLKLE-DAGVYSC----DCGFNKT 854

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREII 976
             + +T++   V F   LQ + E +EG +  L C+ S   V  +W      I       I 
Sbjct: 855  SSTITVNALPVVFTHELQ-NLECDEGGSATLSCELSKPGVPVQWKKGSHIILSGGKYTIK 913

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKL---QDFEVKE 1030
            Q               D G   C+  D+ T+ ++ +K      P  + +    +  + K+
Sbjct: 914  QIASKVELKIADLKCEDEGEYTCVCGDKTTTAIMKIKALKFLSPSAVAETDSQRQKKDKQ 973

Query: 1031 KDVAILEVEINSETADVVWERDG------EIIKP--------------KKNKYDFEKRGH 1070
             +++ L ++   E  + V + DG      E+ KP                 KY  ++ G 
Sbjct: 974  AELSALPIKFMQELLNQVGDEDGSVTLCCELSKPGVPVVWRKGTHVLHSGGKYTIKQVGT 1033

Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130
            I +L I +    D GEY+C   D   TA + V  LP      LQNQ+V +G+  T   EL
Sbjct: 1034 IVELKITDLKPEDAGEYACDCGDNITTASIKVNALPVVFNHELQNQEVQEGDSVTLHCEL 1093

Query: 1131 TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190
            +K    V W K   EI       +   G   +LKI     +DAG Y+C+ G++  TA + 
Sbjct: 1094 SKPGVPVVWRKGTQEIHSGGKYNIKQVGAAVELKIAGVKPEDAGNYACDCGDNITTASIK 1153

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            V    + F+  L   +L   ++   L  E+    + V W K    I    K+ +  D   
Sbjct: 1154 VNALPVVFSRELQNQVLQEGDS-VTLHCELSKPGVPVVWRKGTQEIHSGGKYNIKQDGAA 1212

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRGSDVTLLV 1309
              L I     +D  +Y C   D  S+  +KV  +   P +   E + + I+ G  VTL  
Sbjct: 1213 VELKITDVKPEDAGDYICDCGDNISSANIKVNAL---PVVFKRELQNQGIQEGDSVTLCC 1269

Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
            +    P     W   +++I    K++   + S S  L I  V+  DAG Y      +   
Sbjct: 1270 ELSK-PGVPVTWRKETQVIHSGGKYSIKQVGS-SVELKITDVKPEDAGDYGCDCGESITT 1327

Query: 1369 ADVEMNV-------TILDKPSPPGKPNIL--EIDSSSINICW--DEPENTGNSTIIYYVV 1417
            A++ ++         + ++ +  G+      E+    I + W  D    TG + +    +
Sbjct: 1328 ANIRVDALPAIFTQALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENAVFRCEL 1387

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
                     W   K + +     Q  +  +      Y + E D  + S  TE+ +   + 
Sbjct: 1388 AKSGAKVI-WRKNKRVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQTSAKL 1446

Query: 1478 KIQSP--TVEKPLKNITTEPNEDIELTCI 1504
             ++ P  T+   LK+      ED+   C+
Sbjct: 1447 TVKEPEITILTGLKSCIVNEGEDVHFECL 1475



 Score =  142 bits (344), Expect = 9e-32
 Identities = 162/656 (24%), Positives = 264/656 (40%), Gaps = 62/656 (9%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +  +P  F+ + +    DEG    L C L + P   + W  KG  I+    +S    +  
Sbjct: 860  VNALPVVFTHELQNLECDEGGSATLSCEL-SKPGVPVQWK-KGSHII----LSGGKYTIK 913

Query: 689  HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             +   V LKI ++K   EG YT V     G+ +   ++KIK  +   P  +    S   +
Sbjct: 914  QIASKVELKIADLKCEDEGEYTCVC----GDKTTTAIMKIKALKFLSPSAVAETDSQRQK 969

Query: 748  QGESVILSA----------QVVGNPRPTITWC-KNNKP-VKALPTKSDGDTHS---ITIL 792
            + +   LSA            VG+   ++T C + +KP V  +  K     HS    TI 
Sbjct: 970  KDKQAELSALPIKFMQELLNQVGDEDGSVTLCCELSKPGVPVVWRKGTHVLHSGGKYTIK 1029

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            +   + +  +  LK E++   A            + NA P +F +  Q   V+E  ++ L
Sbjct: 1030 QVGTIVELKITDLKPEDAGEYACDCGDNITTASIKVNALPVVFNHELQNQEVQEGDSVTL 1089

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
               +++  VP + W +  + I           G  +EL I  V  E D+G+Y C      
Sbjct: 1090 HCELSKPGVP-VVWRKGTQEIHSGGKYNIKQVGAAVELKIAGVKPE-DAGNYAC----DC 1143

Query: 913  GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMD 971
            G +   A + ++   V F + LQ     +EG +V L C+ S   V   W    +EI    
Sbjct: 1144 GDNITTASIKVNALPVVFSRELQNQV-LQEGDSVTLHCELSKPGVPVVWRKGTQEIHSGG 1202

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
               I Q+G             D G   C   D  +S  + V      F R+LQ+  ++E 
Sbjct: 1203 KYNIKQDGAAVELKITDVKPEDAGDYICDCGDNISSANIKVNALPVVFKRELQNQGIQEG 1262

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
            D   L  E++     V W ++ ++I     KY  ++ G   +L I +    D G+Y C  
Sbjct: 1263 DSVTLCCELSKPGVPVTWRKETQVIH-SGGKYSIKQVGSSVELKITDVKPEDAGDYGCDC 1321

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD--------- 1142
             +   TA + V  LP      L+NQ   +G   +F+ EL+K D  V W +D         
Sbjct: 1322 GESITTANIRVDALPAIFTQALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENA 1381

Query: 1143 ---------GSEI---------QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
                     G+++         + SN  QL  DG   +L +Y     D GEYSCE  + +
Sbjct: 1382 VFRCELAKSGAKVIWRKNKRVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQ 1441

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
             +A LTV+EP I     L   I+       +  +   D  + V W  +   +++ E
Sbjct: 1442 TSAKLTVKEPEITILTGLKSCIVNEGEDVHFECLVSHDNAVIVQWTLQDVPLQNNE 1497



 Score =  136 bits (328), Expect = 8e-30
 Identities = 134/569 (23%), Positives = 227/569 (39%), Gaps = 54/569 (9%)

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILK 793
            ++  L ++ V +  +     +V       + W  N + +K    +  + +G  H +T  K
Sbjct: 19   IVRELNTVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKESADIEMEKEGTMHRLTF-K 77

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
              K    G     A  S+ +AE    + V+E   E  EP       ++ + KEK +  L 
Sbjct: 78   KTKASMSGPVQFTAGKSKSMAE----LKVKERPIEVLEP------LKDASAKEKTSTTLS 127

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             + +  P   + W++    +  S   +      +++L+I  +++E DSG+Y+C A     
Sbjct: 128  CKFSAPP-KEVNWFKGQTALEASSKYSMKQKDASVQLIIQALNAE-DSGEYRCQAGVCES 185

Query: 914  KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDH 972
            K+       + VE V          E +E    +  C+ ++     +W  N K +   + 
Sbjct: 186  KA------VLKVEDV----------EVDEDGDALFTCEVNYADEEVQWTLNDKPLFNNEV 229

Query: 973  REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKD 1032
              I    +            D G +   ++D + +  L VKE    F++ L D   +EK 
Sbjct: 230  NTITHVDKTHTLSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKG 289

Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
               L+ E +      VW ++   +   K KY+    G    L I + +  D GEYSC L 
Sbjct: 290  TVTLKCEASKPRVAPVWRKESTTLSAGK-KYELLHDGKSLGLSIHDITQADAGEYSCDLG 348

Query: 1093 DESCTAEVTVVEL-----------------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
             + C ++VTV ++                  P I   LQ      G  ATF  EL++   
Sbjct: 349  TDLCKSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGL 408

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEP 1194
             V+W KDG  I+ S   +++ +    KL I +    D+GEYSCEV G     A L ++  
Sbjct: 409  EVKWSKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEIKAD 468

Query: 1195 SIN-FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
              N F   L +      N+D     E       VTW K    I+   ++ L        L
Sbjct: 469  LANKFICELKD-ATADENSDVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILIL 527

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             ++   + D   YTC +   K+T KL V+
Sbjct: 528  KVKDLEKSDSEVYTCDIGSTKTTAKLTVK 556



 Score =  124 bits (300), Expect = 2e-26
 Identities = 131/555 (23%), Positives = 222/555 (40%), Gaps = 63/555 (11%)

Query: 665  IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
            + W   GE++    +I +  E  MH     L     K    G     A    G++     
Sbjct: 48   VKWTLNGEQLKESADIEMEKEGTMHR----LTFKKTKASMSGPVQFTA----GKSKSMAE 99

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-- 782
            LK+K   + P +V+EPLK    ++  S  LS +    P+  + W K    ++A    S  
Sbjct: 100  LKVK---ERPIEVLEPLKDASAKEKTSTTLSCKFSAPPKE-VNWFKGQTALEASSKYSMK 155

Query: 783  DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
              D     I++    +D G Y  +A    G+ E+ AV+ VE+                 +
Sbjct: 156  QKDASVQLIIQALNAEDSGEYRCQA----GVCESKAVLKVED-----------------V 194

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
             V E G       V       + W  N++ +  +E  T     +   L + N+  E D G
Sbjct: 195  EVDEDGDALFTCEVNYAD-EEVQWTLNDKPLFNNEVNTITHVDKTHTLSLKNLAPE-DGG 252

Query: 903  DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWY 961
                  S S         + +  +K  F+K L      E+G TV L+C+ S   V+  W 
Sbjct: 253  K----VSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKG-TVTLKCEASKPRVAPVWR 307

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET------ 1015
                 +S     E++ +G+            D G   C +      + + V++       
Sbjct: 308  KESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCDLGTDLCKSKVTVRDIHIGITK 367

Query: 1016 -----------IPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064
                        P   ++LQ    K  + A    E++    +V W +DG+ I+ K  KY+
Sbjct: 368  RIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGLEVKWSKDGKSIR-KSQKYE 426

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSC-ILRDESCTAEVTV-VELPPEIITRLQNQKVNKGN 1122
              +   + KL IRN +  D GEYSC +    +  A++ +  +L  + I  L++   ++ +
Sbjct: 427  ISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEIKADLANKFICELKDATADENS 486

Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              +FE E  +    V W K   EI+     +LT  G    LK+ D +  D+  Y+C++G+
Sbjct: 487  DVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVKDLEKSDSEVYTCDIGS 546

Query: 1183 SKCTAILTVEEPSIN 1197
            +K TA LTV+E   N
Sbjct: 547  TKTTAKLTVKEHHYN 561



 Score =  114 bits (274), Expect = 3e-23
 Identities = 119/550 (21%), Positives = 207/550 (37%), Gaps = 40/550 (7%)

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            +N +    +     + V E         V+   V  + W  N E +  S  I    +G  
Sbjct: 12   QNEQAISIVRELNTVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKESADIEMEKEGTM 71

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
              L      + + SG  +     +AGKS   A + +    +  ++ L+ +   E+  T  
Sbjct: 72   HRLTFKKTKASM-SGPVQF----TAGKSKSMAELKVKERPIEVLEPLKDASAKEKTSTT- 125

Query: 948  LECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
            L C+ S       W+  +  +       + Q+              D G  +C     E+
Sbjct: 126  LSCKFSAPPKEVNWFKGQTALEASSKYSMKQKDASVQLIIQALNAEDSGEYRCQAGVCES 185

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE-RDGEIIKPKKNKYDF 1065
              +L           K++D EV E   A+   E+N    +V W   D  +   + N    
Sbjct: 186  KAVL-----------KVEDVEVDEDGDALFTCEVNYADEEVQWTLNDKPLFNNEVNTITH 234

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125
              + H   L ++N +  D G+ S  +RD   T  + V E     +  L +    +    T
Sbjct: 235  VDKTHT--LSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKGTVT 292

Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
             + E +K      W K+ + +      +L  DGK   L I+D    DAGEYSC++G   C
Sbjct: 293  LKCEASKPRVAPVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCDLGTDLC 352

Query: 1186 TAILTVEEPSINFTLRLPEF----------------ILVPANTDAYLTVEIPDETLDVTW 1229
             + +TV +  I  T R+                   +      DA  T E+    L+V W
Sbjct: 353  KSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGLEVKW 412

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288
             K    I  ++K+ +  +     L IR  T+ D  EY+C +     T+K K+E+  +   
Sbjct: 413  SKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGG-PTSKAKLEIKADLAN 471

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
            K +   ++      SDV+   +  A P     W+  +K IK     + +       L +K
Sbjct: 472  KFICELKDATADENSDVSFECE-TAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVK 530

Query: 1349 KVENTDAGIY 1358
             +E +D+ +Y
Sbjct: 531  DLEKSDSEVY 540



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 164/832 (19%), Positives = 329/832 (39%), Gaps = 82/832 (9%)

Query: 915  SSHGARVTI--DVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVS-TKWYHNKKEISGM 970
            +S+ A++ +  + + ++ V+ L  + E  E      E + S  TV   KW  N +++   
Sbjct: 2    TSYDAQICLAQNEQAISIVRELN-TVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKES 60

Query: 971  DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030
               E+ +EG               G ++      ++   L VKE   E +  L+D   KE
Sbjct: 61   ADIEMEKEGTMHRLTFKKTKASMSGPVQFTAGKSKSMAELKVKERPIEVLEPLKDASAKE 120

Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            K    L  + ++   +V W + G+      +KY  +++    +L I+  +  D GEY C 
Sbjct: 121  KTSTTLSCKFSAPPKEVNWFK-GQTALEASSKYSMKQKDASVQLIIQALNAEDSGEYRC- 178

Query: 1091 LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150
                    +  V E   + + ++++ +V++   A F  E+   D  V+W  +   + F+N
Sbjct: 179  --------QAGVCE--SKAVLKVEDVEVDEDGDALFTCEVNYADEEVQWTLNDKPL-FNN 227

Query: 1151 HIQ-LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209
             +  +T   K   L + +   +D G+ S  + + K T  L V+E    F L+L + ++  
Sbjct: 228  EVNTITHVDKTHTLSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIF-LKLLDDVVAE 286

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                  L  E     +   W K+ + +   +K+ L+ D K   L I   T+ D  EY+C 
Sbjct: 287  EKGTVTLKCEASKPRVAPVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCD 346

Query: 1270 LLDAKSTTKLKVEVVEF---------------PPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
            L      +K+ V  +                  P I    +    K G D T   +    
Sbjct: 347  LGTDLCKSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQ- 405

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN-CGHADVEM 1373
                 +W  + K I+K +  + S +     LTI+ V + D+G Y   +       A +E+
Sbjct: 406  SGLEVKWSKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEI 465

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI------DTTE- 1426
               + +K     K    + ++S ++    E E    +T + ++   +EI      + T+ 
Sbjct: 466  KADLANKFICELKDATAD-ENSDVSF---ECETAQPATKVTWLKGTKEIKAGGRYELTQK 521

Query: 1427 ----WISVKNITKTQT-----SIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIK 1475
                 + VK++ K+ +      I + KT +    + +  N++    S  S        +K
Sbjct: 522  GAILILKVKDLEKSDSEVYTCDIGSTKTTAKLTVKEHHYNKLIPSSSQPSNPPSCLLDVK 581

Query: 1476 ETK--------IQSPTV----EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
              K        +QSP +    ++ +KN      E + L+C+    P  +V W +  + LK
Sbjct: 582  TVKNHFKYMILVQSPVLPAKFKEQMKNQQVTEGEKVLLSCML-SKPGCQVQWKKGTECLK 640

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSCVVGIQQKPVITISNEDIKQ 1582
                 Y+                      ++ + G  +T+  + +   PV+   +E   Q
Sbjct: 641  NG-GRYQIMQRDTIFELQISELAVEDSGEYSCECGNEKTTANLVVSALPVV-FKHELQSQ 698

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            + + GD   +   +   P   V+W K    L + ++Y I        ++I +LK     +
Sbjct: 699  ECEGGDTVTLNCELSK-PGVPVVWKKGTQVLHSGEKYLIKQDGANVELKIADLKLEDGGQ 757

Query: 1643 YTIEASNTAGTSSVEVTL-----KVYD-KPSKPEGPVIMREISRESVTIEWK 1688
            YT    +   T+++++       +++D K  + +   +  E+S+  V + W+
Sbjct: 758  YTCLCGDKKTTANIKIKALNFKRELHDMKCQEADSVTLQCELSKPGVPVVWR 809



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 105/469 (22%), Positives = 185/469 (39%), Gaps = 50/469 (10%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +  +P  F+ + + Q V EG  + L C L + P   + W    +EI      ++      
Sbjct: 1065 VNALPVVFNHELQNQEVQEGDSVTLHCEL-SKPGVPVVWRKGTQEIHSGGKYNIK----- 1118

Query: 689  HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             +  +V LKI  VK    G Y     +    AS+ +          P      L++ +++
Sbjct: 1119 QVGAAVELKIAGVKPEDAGNYACDCGDNITTASIKV-------NALPVVFSRELQNQVLQ 1171

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            +G+SV L  ++   P   + W K  + + +    +     +   LK   VK E       
Sbjct: 1172 EGDSVTLHCEL-SKPGVPVVWRKGTQEIHSGGKYNIKQDGAAVELKITDVKPEDAGDYIC 1230

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            +  + I+  SA I V      NA P +F    Q   ++E  ++ L   +++  VP +TW 
Sbjct: 1231 DCGDNIS--SANIKV------NALPVVFKRELQNQGIQEGDSVTLCCELSKPGVP-VTWR 1281

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA-------- 919
            +  ++I      +    G ++EL IT+V  E D+GDY C    S   ++           
Sbjct: 1282 KETQVIHSGGKYSIKQVGSSVELKITDVKPE-DAGDYGCDCGESITTANIRVDALPAIFT 1340

Query: 920  -----RVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQTSHT-VSTKWYHNK 964
                 +  ++ E ++F   L K           ETE G+  +  C+ + +     W  NK
Sbjct: 1341 QALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENAVFRCELAKSGAKVIWRKNK 1400

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
            + I   +  ++ Q+G             D G   C  +  +TS  L VKE     +  L+
Sbjct: 1401 RVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQTSAKLTVKEPEITILTGLK 1460

Query: 1025 DFEVKEKDVAILEVEINSETADVV-WE-RDGEIIKPKKNKYDFEKRGHI 1071
               V E +    E  ++ + A +V W  +D  +   + NK   E RG I
Sbjct: 1461 SCIVNEGEDVHFECLVSHDNAVIVQWTLQDVPLQNNEMNKIGMEVRGKI 1509



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 39/139 (28%), Positives = 71/139 (51%), Gaps = 4/139 (2%)

Query: 1024 QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
            +D E +  + A+   E+    A V+W ++  +I+   NKY  ++ G + +L +      D
Sbjct: 1371 RDLETETGENAVFRCELAKSGAKVIWRKNKRVIEAS-NKYQLKQDGAVAELIVYKLQEGD 1429

Query: 1084 EGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKD 1142
             GEYSC    +  +A++TV E    I+T L++  VN+G    FE  ++  +A +V+W   
Sbjct: 1430 CGEYSCETEHDQTSAKLTVKEPEITILTGLKSCIVNEGEDVHFECLVSHDNAVIVQWTLQ 1489

Query: 1143 GSEIQFS--NHIQLTIDGK 1159
               +Q +  N I + + GK
Sbjct: 1490 DVPLQNNEMNKIGMEVRGK 1508



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 77/382 (20%), Positives = 148/382 (38%), Gaps = 32/382 (8%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            VDE  D L  C  V   + ++ W    + +  +E  ++      H     L + N+   +
Sbjct: 196  VDEDGDALFTCE-VNYADEEVQWTLNDKPLFNNEVNTITHVDKTH----TLSLKNLAP-E 249

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            +G     ++    E    + LK+K  EK+    ++ L  ++  +  +V L  +    PR 
Sbjct: 250  DGGKVSFSIRDVKET---VCLKVK--EKKAI-FLKLLDDVVAEEKGTVTLKCEA-SKPRV 302

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK-----AENSEGIAET 816
               W K +  + A        DG +  ++I    +  D G Y+        ++   + + 
Sbjct: 303  APVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQA-DAGEYSCDLGTDLCKSKVTVRDI 361

Query: 817  SAVIT--VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
               IT  ++    +  E P      Q ++ K          ++++ +  + W ++ + I 
Sbjct: 362  HIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGL-EVKWSKDGKSIR 420

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVKH 933
             S+    + +   ++L I NV  + DSG+Y C  +   G  +  A++ I  +    F+  
Sbjct: 421  KSQKYEISQEQTLVKLTIRNVTDK-DSGEYSCEVT---GGPTSKAKLEIKADLANKFICE 476

Query: 934  LQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
            L K    +E   V  EC+T+   +   W    KEI      E+ Q+G             
Sbjct: 477  L-KDATADENSDVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVKDLEKS 535

Query: 993  DVGVIKCIVKDQETSTMLVVKE 1014
            D  V  C +   +T+  L VKE
Sbjct: 536  DSEVYTCDIGSTKTTAKLTVKE 557


>UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 15 SCAF14556, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 2224

 Score =  162 bits (394), Expect = 8e-38
 Identities = 151/643 (23%), Positives = 267/643 (41%), Gaps = 40/643 (6%)

Query: 750  ESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            +  +LS  V  +P+  + W K+ K     + +  +S G    + I   ++ KD G Y+ +
Sbjct: 1112 QKAVLSCDVT-DPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDSVER-KDAGEYSCE 1169

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGTIKLVARV---TRNPVP 862
                 GI +    + V +    +A    F N  Q+   KE K T+   A +     +   
Sbjct: 1170 V----GIEKLLFKLHVTDLQVRSA----FCN--QDSVQKEIKATVSQKASLCCEVSDSKT 1219

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---HGA 919
             + WY++ +++  S TI     G++  LV+ +VD + D+G+Y C A             A
Sbjct: 1220 EVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKK-DAGEYVCEAGTEKLTFKIHVEAA 1278

Query: 920  RVTIDVEKVTFVKH-LQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEIS--GMDHREI 975
            R  +  +     K  +Q   +T   +  IL C+ + +    KWY + K++S     H+E 
Sbjct: 1279 RAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWYKDGKQLSPSAAVHKEA 1338

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK---LQDFEVKEKD 1032
              +G+            D G   C+   ++ +  + V E    F  K    ++       
Sbjct: 1339 --KGKLRQLVIRSTEKKDAGEYTCVAGTEKLAFNVQVAEIKSAFSNKEAVQKEVTAAISQ 1396

Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
             A L  E++    +V W +DG+++ P K  +  E +G  R+L I +    D GEY C   
Sbjct: 1397 KATLGCEVSDLRTEVRWYKDGKLLTPTKTLHT-EVKGKGRQLVIDSIEKKDAGEYICEAG 1455

Query: 1093 DESCTAEVTVVELPPEIITR---LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS 1149
             E     + V E P     +       K +   KAT   E++     V+W+KDG  +  +
Sbjct: 1456 TEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEVSDPKTAVKWYKDGKLLSST 1515

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP-EFILV 1208
              +     GK ++L I   D  DAGEY+CE G  K    L + + ++ F  +L  E  +V
Sbjct: 1516 KAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLFKLQMTDAAVRFQKKLDNETCVV 1575

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
             A  +  LT E+  E   V W++    ++D++K+ +  D   R+L+++     D   Y+C
Sbjct: 1576 QAGENIVLTAELTAENGSVKWFRDGVELKDSKKYEMRKDGFSRSLVVKATETKDSGSYSC 1635

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
               D K   + KV+V E   K V   +   ++    ++L+ +       +  W    + I
Sbjct: 1636 QTTDDK--LEYKVQVKELALKFVVPLKAATVELEGTLSLVCELNQ-ASGDVAWKHKGRDI 1692

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
            K         +     LT+  +   D G Y     N+   A V
Sbjct: 1693 KPGGRYSVRTNGPQRILTVTNISTEDEGDYSCECRNDKTSATV 1735



 Score =  146 bits (353), Expect = 8e-33
 Identities = 125/528 (23%), Positives = 225/528 (42%), Gaps = 35/528 (6%)

Query: 641  KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
            KA  V+    + L C L      D+AW  KG +I P    SV           +L +TN+
Sbjct: 1660 KAATVELEGTLSLVCELNQA-SGDVAWKHKGRDIKPGGRYSVRTNGPQR----ILTVTNI 1714

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
                EG Y+    N +  A+      + T      ++   L ++   +G+  I    V  
Sbjct: 1715 STEDEGDYSCECRNDKTSAT------VSTRAPRQVRLTTKLNNVAAMEGKDAIFKCAVTP 1768

Query: 761  NPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
                ++ W   + P+ A      +  G+ HS+T+    + +D G  + +AE         
Sbjct: 1769 ADA-SVRWFHKSLPIAAGIKYKMEHSGNCHSLTVTSVSQ-QDAGEVSFEAEGKS----CK 1822

Query: 818  AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
            A + V+       EP +F  + + +TV+E+   KL   +++ P   + W +N+ +I P+ 
Sbjct: 1823 ANLQVQH------EPVMFKEKLENLTVEEQSEAKLEVELSK-PSEEVRWMKNSVVIQPTG 1875

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
             I    DG    LV  +V S  D G Y C   +   +    A+++++++K+  +K L ++
Sbjct: 1876 NIKIRTDGAKQALVFMSV-SRADRGVYSCETLDDKTQ----AKLSVEMKKIQVIKGLTET 1930

Query: 938  YETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
                E +TV LE + S   V   W  +   +    +  I   GR            D G 
Sbjct: 1931 -TAHETETVTLEIELSQADVDGSWTKDGVNVKSGGNCRITALGRKQTLTLSNLKMEDAGT 1989

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
                      S  L V E      + + D  V EK+    + E++    +V W +D   +
Sbjct: 1990 FVFQADGIRVSGKLTVLEPPAMISKPIMDVSVAEKEKVTFDCEVSRTNTEVKWFKDNVEL 2049

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
            KP K        G  R L I   +  D G Y C   D++ +A++TV     +I+ +LQ+ 
Sbjct: 2050 KPGK-MVGIHSLGRKRTLVINKCTPEDAGTYICRTPDDNTSAKLTVNARDIKIVKKLQDV 2108

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            +V +   ATF  EL+  +   +W+K G++++ S++I++  +G  ++ K
Sbjct: 2109 EVMEKESATFVCELSHDEVDSQWWKGGTKLKASDNIKMRQEGITKRTK 2156



 Score =  131 bits (316), Expect = 2e-28
 Identities = 148/626 (23%), Positives = 246/626 (39%), Gaps = 36/626 (5%)

Query: 759  VGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            V +P+  + W K+ K     KA+ ++S G    + I K  K KD G YT +    + + +
Sbjct: 1496 VSDPKTAVKWYKDGKLLSSTKAVHSESKGKIRELVIEKMDK-KDAGEYTCETGTEKLLFK 1554

Query: 816  ---TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
               T A +  ++  +            +   V+    I L A +T     S+ W+R+   
Sbjct: 1555 LQMTDAAVRFQKKLDN-----------ETCVVQAGENIVLTAELTAEN-GSVKWFRDGVE 1602

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +  S+      DG +  LV+   +++ DSG Y C  ++   K  +  +V +    + FV 
Sbjct: 1603 LKDSKKYEMRKDGFSRSLVVKATETK-DSGSYSCQTTDD--KLEY--KVQVKELALKFVV 1657

Query: 933  HLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
             L+ +    EG T+ L C+ +       W H  ++I       +   G            
Sbjct: 1658 PLKAATVELEG-TLSLVCELNQASGDVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNIST 1716

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV 1048
             D G   C  ++ +TS    V    P  +R   KL +    E   AI +  +    A V 
Sbjct: 1717 EDEGDYSCECRNDKTSA--TVSTRAPRQVRLTTKLNNVAAMEGKDAIFKCAVTPADASVR 1774

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W      I     KY  E  G+   L + + S  D GE S     +SC A + V   P  
Sbjct: 1775 WFHKSLPIAAGI-KYKMEHSGNCHSLTVTSVSQQDAGEVSFEAEGKSCKANLQVQHEPVM 1833

Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
               +L+N  V + ++A  E+EL+K    VRW K+   IQ + +I++  DG KQ L     
Sbjct: 1834 FKEKLENLTVEEQSEAKLEVELSKPSEEVRWMKNSVVIQPTGNIKIRTDGAKQALVFMSV 1893

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228
               D G YSCE  + K  A L+VE   I     L E       T   L +E+    +D +
Sbjct: 1894 SRADRGVYSCETLDDKTQAKLSVEMKKIQVIKGLTETTAHETET-VTLEIELSQADVDGS 1952

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288
            W K    ++      + +  +K+TL +     +D   +       + + KL   V+E P 
Sbjct: 1953 WTKDGVNVKSGGNCRITALGRKQTLTLSNLKMEDAGTFVFQADGIRVSGKL--TVLEPPA 2010

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
             I     +  +     VT   +         +W  ++  +K  K        +  +L I 
Sbjct: 2011 MISKPIMDVSVAEKEKVTFDCEVSR-TNTEVKWFKDNVELKPGKMVGIHSLGRKRTLVIN 2069

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMN 1374
            K    DAG Y  R  ++   A + +N
Sbjct: 2070 KCTPEDAGTYICRTPDDNTSAKLTVN 2095



 Score =  130 bits (314), Expect = 4e-28
 Identities = 190/913 (20%), Positives = 341/913 (37%), Gaps = 84/913 (9%)

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            I++  K  DEG Y+ +    +   +     T       + E    + +  + +V +K T+
Sbjct: 860  IIRNAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKET---VQKEVKASVSQKATL 916

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
                  T+  V    WY++ +++  S TI     G   +LVI  V+   D+G+Y C A  
Sbjct: 917  SCNVSDTKTEVK---WYKDGKLLISSRTIYSEAKGNTRQLVIEKVEKS-DAGEYTCEAGG 972

Query: 911  S----------AGKSSHGARVTIDVEKVT-FVKHLQKSYETEEG----KTVILECQTSHT 955
                          SS  A V      +T F+  L   +           V    +    
Sbjct: 973  DKLVFTITVTGTRTSSTNACVRQIFNTITLFLPPLHSCFVLPAAIIYYAIVNRHIKIEPL 1032

Query: 956  VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET 1015
            V    + ++ + + ++   + +EG+            D G   C    ++    + V E 
Sbjct: 1033 VFFCLFPSEAQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICESGSEKLVFRIQVAEA 1092

Query: 1016 IPEFIRK---LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
               F +K    +D +      A+L  ++     +V W +DG+++   +  +  E +G  R
Sbjct: 1093 PSAFFKKESIQKDVKASVSQKAVLSCDVTDPKTEVKWYKDGKLLTSTRMVH-VESKGKNR 1151

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-------KVNKGNKAT 1125
            +L I +    D GEYSC +  E    ++ V +L  ++ +   NQ       K     KA+
Sbjct: 1152 QLVIDSVERKDAGEYSCEVGIEKLLFKLHVTDL--QVRSAFCNQDSVQKEIKATVSQKAS 1209

Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
               E++     V+W+KDG  +  S  I     GK + L +   D  DAGEY CE G  K 
Sbjct: 1210 LCCEVSDSKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVCEAGTEKL 1269

Query: 1186 TAILTVE----EPSINFTLRLPEFILVPANT----DAYLTVEIPDETLDVTWYKKKSVIE 1237
            T  + VE    E          E +     T       L+ E+ D   +V WYK    + 
Sbjct: 1270 TFKIHVEAARAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWYKDGKQLS 1329

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYER 1295
             +      +  K R L+IR   + D  EYTCV    K    ++V  ++  F  K    ++
Sbjct: 1330 PSAAVHKEAKGKLRQLVIRSTEKKDAGEYTCVAGTEKLAFNVQVAEIKSAFSNKEA-VQK 1388

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            E         TL  +     +    W  + K++   K     +  K   L I  +E  DA
Sbjct: 1389 EVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQLVIDSIEKKDA 1447

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
            G Y        G   V   + + + P+      +++ +  +          +  +T+   
Sbjct: 1448 GEYIC----EAGTEKVVFRINVAEAPAIFSNKELVKTEVKA--------SLSQKATLSCE 1495

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE---TTEYYK 1472
            V + +     +W       K  +S + + + S  + R   + ++D  DA E    T   K
Sbjct: 1496 VSDPK--TAVKWY---KDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEK 1550

Query: 1473 VIKETKIQSPTV--EKPLKNIT--TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
            ++ + ++    V  +K L N T   +  E+I LT          V W+RDG +LK +K  
Sbjct: 1551 LLFKLQMTDAAVRFQKKLDNETCVVQAGENIVLTAEL-TAENGSVKWFRDGVELKDSK-K 1608

Query: 1529 YENR-----XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583
            YE R                    Y C   +D  E +   V  +  K V+ +    ++ +
Sbjct: 1609 YEMRKDGFSRSLVVKATETKDSGSYSCQTTDDKLEYKVQ-VKELALKFVVPLKAATVELE 1667

Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
               G   LV  + +     +V W   G  ++    Y++ T     ++ +  +       Y
Sbjct: 1668 ---GTLSLVCELNQA--SGDVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNISTEDEGDY 1722

Query: 1644 TIEASNTAGTSSV 1656
            + E  N   +++V
Sbjct: 1723 SCECRNDKTSATV 1735



 Score =  126 bits (305), Expect = 5e-27
 Identities = 136/613 (22%), Positives = 246/613 (40%), Gaps = 37/613 (6%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  G +I+L   L A     + W   G E+   +   +    D      V+K T  K   
Sbjct: 1575 VQAGENIVLTAELTA-ENGSVKWFRDGVELKDSKKYEM--RKDGFSRSLVVKATETK--D 1629

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G+Y+    + + E       K++  E     V+ PLK+  V    ++ L  ++      
Sbjct: 1630 SGSYSCQTTDDKLE------YKVQVKELALKFVV-PLKAATVELEGTLSLVCEL-NQASG 1681

Query: 765  TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             + W    + +K       +++G    +T+      +DEG Y+ +  N +    TSA ++
Sbjct: 1682 DVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNIS-TEDEGDYSCECRNDK----TSATVS 1736

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
               P +          +   +   E         VT     S+ W+  +  I+       
Sbjct: 1737 TRAPRQVR-----LTTKLNNVAAMEGKDAIFKCAVTPADA-SVRWFHKSLPIAAGIKYKM 1790

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
               G    L +T+V S+ D+G+   V+  + GKS   A + +  E V F + L+ +   E
Sbjct: 1791 EHSGNCHSLTVTSV-SQQDAGE---VSFEAEGKSCK-ANLQVQHEPVMFKEKLE-NLTVE 1844

Query: 942  EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            E     LE + S  +   +W  N   I    + +I  +G             D GV  C 
Sbjct: 1845 EQSEAKLEVELSKPSEEVRWMKNSVVIQPTGNIKIRTDGAKQALVFMSVSRADRGVYSCE 1904

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
              D +T   L V+    + I+ L +    E +   LE+E++    D  W +DG  +K   
Sbjct: 1905 TLDDKTQAKLSVEMKKIQVIKGLTETTAHETETVTLEIELSQADVDGSWTKDGVNVKSGG 1964

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120
            N       G  + L + N  + D G +         + ++TV+E P  I   + +  V +
Sbjct: 1965 N-CRITALGRKQTLTLSNLKMEDAGTFVFQADGIRVSGKLTVLEPPAMISKPIMDVSVAE 2023

Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
              K TF+ E+++ +  V+WFKD  E++    + +   G+K+ L I  C  +DAG Y C  
Sbjct: 2024 KEKVTFDCEVSRTNTEVKWFKDNVELKPGKMVGIHSLGRKRTLVINKCTPEDAGTYICRT 2083

Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
             +   +A LTV    I    +L + + V     A    E+  + +D  W+K  + ++ ++
Sbjct: 2084 PDDNTSAKLTVNARDIKIVKKLQD-VEVMEKESATFVCELSHDEVDSQWWKGGTKLKASD 2142

Query: 1241 KFTLISD-VKKRT 1252
               +  + + KRT
Sbjct: 2143 NIKMRQEGITKRT 2155



 Score =  113 bits (273), Expect = 4e-23
 Identities = 183/869 (21%), Positives = 321/869 (36%), Gaps = 92/869 (10%)

Query: 960  WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019
            W  N +E+      E + E R            DVGV +C++ D   S  L +K+   +F
Sbjct: 743  WMRNGREVKVGKKYEYVSEERKRILLVHNVTEEDVGVYECVLADDSMSIQLALKDEPAKF 802

Query: 1020 IRKLQD---FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
            + K +         K    L  ++   +A VVW +D ++   +  +  F  +G  RKL I
Sbjct: 803  LNKARGPMGLASSLKGDLELSCDVTPASALVVWRKD-QVEITEDQRTIFISKGTQRKLII 861

Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEII-----TRLQNQKVNKGNKATFEIELT 1131
            RN    DEG YSC    +  T +V + E           T  +  K +   KAT    ++
Sbjct: 862  RNAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKETVQKEVKASVSQKATLSCNVS 921

Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
                 V+W+KDG  +  S  I     G  ++L I   +  DAGEY+CE G  K    +TV
Sbjct: 922  DTKTEVKWYKDGKLLISSRTIYSEAKGNTRQLVIEKVEKSDAGEYTCEAGGDKLVFTITV 981

Query: 1192 ---EEPSIN---------FTLRLPEF---ILVPANTDAYLTV--EIPDETL-DVTWYKKK 1233
                  S N          TL LP      ++PA    Y  V   I  E L     +  +
Sbjct: 982  TGTRTSSTNACVRQIFNTITLFLPPLHSCFVLPAAIIYYAIVNRHIKIEPLVFFCLFPSE 1041

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP---KI 1290
            +      + ++  + + R L+I      D  EY C           +++V E P    K 
Sbjct: 1042 AQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICE--SGSEKLVFRIQVAEAPSAFFKK 1099

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350
               +++ +        L  D    P+   +W  + K++   +        K+  L I  V
Sbjct: 1100 ESIQKDVKASVSQKAVLSCDV-TDPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDSV 1158

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
            E  DAG Y   +    G   +   + + D          L++ S+  N   D  +    +
Sbjct: 1159 ERKDAGEYSCEV----GIEKLLFKLHVTD----------LQVRSAFCN--QDSVQKEIKA 1202

Query: 1411 TIIYYVVEYQEI-DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE--- 1466
            T+        E+ D+   +      K   S + + T S  + R   V  VD  DA E   
Sbjct: 1203 TVSQKASLCCEVSDSKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVC 1262

Query: 1467 -------TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG---GVPQPKVTWY 1516
                   T + +      ++Q+ +     +++ TE    +    I          +V WY
Sbjct: 1263 EAGTEKLTFKIHVEAARAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWY 1322

Query: 1517 RDGKKLKTAKATYENR----XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
            +DGK+L  + A ++                     Y C+A    G  + +  V + +   
Sbjct: 1323 KDGKQLSPSAAVHKEAKGKLRQLVIRSTEKKDAGEYTCVA----GTEKLAFNVQVAEIK- 1377

Query: 1573 ITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
               SN++  QK     +  +  +   +  +   EV WYK+G  L   K  +   K K   
Sbjct: 1378 SAFSNKEAVQKEVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQ 1436

Query: 1630 IRIKELKRSHSSKYTIEAS--------NTAGTSSV---EVTLKVYDKPSKPEGPVIMREI 1678
            + I  +++  + +Y  EA         N A   ++   +  +K   K S  +   +  E+
Sbjct: 1437 LVIDSIEKKDAGEYICEAGTEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEV 1496

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD-RDVETYCIQKLNENCEY 1737
            S     ++W     DG L  +  A+        R + +  +D +D   Y  +   E   +
Sbjct: 1497 SDPKTAVKW---YKDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLF 1553

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDV 1766
              + +    V F + L++E  V++   ++
Sbjct: 1554 KLQ-MTDAAVRFQKKLDNETCVVQAGENI 1581



 Score =  102 bits (245), Expect = 9e-20
 Identities = 77/288 (26%), Positives = 128/288 (44%), Gaps = 15/288 (5%)

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV---KEKDVAILEVEINSETADVVW 1049
            D  V+K +    ++S  L VK     F  K    E+     +  A L  E++   A VVW
Sbjct: 684  DGTVVKFVGGGSQSSCTLSVKAPPVRFTNKSVTLELVTCSAQATAQLTAEVSDYDAQVVW 743

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109
             R+G  +K  K KY++      R L + N +  D G Y C+L D+S + ++ + + P + 
Sbjct: 744  MRNGREVKVGK-KYEYVSEERKRILLVHNVTEEDVGVYECVLADDSMSIQLALKDEPAKF 802

Query: 1110 ITRLQNQK-VNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
            + + +    +    K   E+  ++T   ALV W KD  EI           G ++KL I 
Sbjct: 803  LNKARGPMGLASSLKGDLELSCDVTPASALVVWRKDQVEITEDQRTIFISKGTQRKLIIR 862

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDAYLTVEIPD 1222
            +    D G YSCE    K T  + ++E     + +    + + +    +  A L+  + D
Sbjct: 863  NAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKETVQKEVKASVSQKATLSCNVSD 922

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVK--KRTLIIRKCTEDDQCEYTC 1268
               +V WYK   ++  +   T+ S+ K   R L+I K  + D  EYTC
Sbjct: 923  TKTEVKWYKDGKLLISSR--TIYSEAKGNTRQLVIEKVEKSDAGEYTC 968



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 118/556 (21%), Positives = 218/556 (39%), Gaps = 41/556 (7%)

Query: 1130 LTKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SK 1184
            L KG    R   DG+ I +   H+      +   LK+  C   D G Y+C   N    + 
Sbjct: 270  LPKG-VFTRTCTDGTNISEGRRHVIYEDHAENFILKVLYCKQSDNGLYTCNAANMAGQTY 328

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
               ++TV+EP + F  +L + + V     A L  E+P       W+ +++ +E + K+ +
Sbjct: 329  SAVLVTVKEPQVPFRRKLQD-VEVQEKKSAMLMCEVPLVATHTNWFMEETRLEQSSKYHM 387

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304
              +   R L I   T +D   Y C + +   T            K+    R   +     
Sbjct: 388  EQEGTLRRLTIHNVTTNDDGVYICEMKEGSRTVAELTVRGNITKKL---PRRTVVPISDT 444

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
            V   V+ +  P  +  W  NS+ +K+      +   +  +LTI+     D+G     +  
Sbjct: 445  VIFCVELE-HPCADAYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAF-VAG 502

Query: 1365 NCGHADVEMNVTILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
            +C        VT   K  P  P    I     SSI I W  P++     I  Y+VE +++
Sbjct: 503  DC-KTSTRFTVTAARKHPPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKV 561

Query: 1423 DTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET--TEYYKVIKET 1477
                W      + IT T+ ++ +    +SY+FR  A+N+   S   E   + Y + + E 
Sbjct: 562  GNKTWQRCNAGETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLEVPGSFYLEPLAE- 620

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---ENRXX 1534
                  V K L N T    E+  ++     V      W  DG+ L++  A Y    ++  
Sbjct: 621  ------VTKGLINSTAVAGEEFSISVGLSAVCSG--FWSLDGRLLRSG-ADYLITRSKTT 671

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                            + F   G  ++SC + ++  PV   +N+ +  +           
Sbjct: 672  HTLLIRCVTAEMDGTVVKFVGGGS-QSSCTLSVKAPPV-RFTNKSVTLELVTCSAQATAQ 729

Query: 1595 VIEGIPP--PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            +   +     +V+W +NG +++  K+Y   ++E+  ++ +  +       Y  E      
Sbjct: 730  LTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILLVHNVTEEDVGVY--ECVLADD 787

Query: 1653 TSSVEVTLKVYDKPSK 1668
            + S+++ LK  D+P+K
Sbjct: 788  SMSIQLALK--DEPAK 801



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 128/630 (20%), Positives = 244/630 (38%), Gaps = 47/630 (7%)

Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT-AILTVEEPSINF 1198
            F   ++  F N   +  +G+ ++L I   +  DAGEY CE G+ K    I   E PS  F
Sbjct: 1038 FPSEAQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICESGSEKLVFRIQVAEAPSAFF 1097

Query: 1199 TLR-LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
                + + +    +  A L+ ++ D   +V WYK   ++  T    + S  K R L+I  
Sbjct: 1098 KKESIQKDVKASVSQKAVLSCDVTDPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDS 1157

Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAF 1314
                D  EY+C +   K   KL V  ++      + +   +E +       +L  +    
Sbjct: 1158 VERKDAGEYSCEVGIEKLLFKLHVTDLQVRSAFCNQDSVQKEIKATVSQKASLCCEVSD- 1216

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY-------KL--RLENN 1365
             +   +W  + K++   +        KS  L ++ V+  DAG Y       KL  ++   
Sbjct: 1217 SKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVCEAGTEKLTFKIHVE 1276

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
               A+V+     L+K S   +   + +   +I  C    E   N+T + +  + +++  +
Sbjct: 1277 AARAEVQAKSAFLNKESVQTEVKTI-LSQKTILSC----ELADNATEVKWYKDGKQLSPS 1331

Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
              +      + +  ++ L   S+ +  A    E      +E   +   + E K      E
Sbjct: 1332 AAVH----KEAKGKLRQLVIRSTEKKDA---GEYTCVAGTEKLAFNVQVAEIKSAFSNKE 1384

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
               K +T   ++   L C    + + +V WY+DGK L   K  +                
Sbjct: 1385 AVQKEVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQLVIDSIE 1443

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
                     + G  +    + + + P I  + E +K + K       T   E   P   +
Sbjct: 1444 KKDAGEYICEAGTEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEVSDPKTAV 1503

Query: 1606 -WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT----- 1659
             WYK+G  L + K  +  +K K   + I+++ +  + +YT E         +++T     
Sbjct: 1504 KWYKDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLFKLQMTDAAVR 1563

Query: 1660 -LKVYDKPS----KPEGPVIMREISRESVTIEWKPPLDDGGLEL---TKYAIEKHEPDNN 1711
              K  D  +      E  V+  E++ E+ +++W     D G+EL    KY + K     +
Sbjct: 1564 FQKKLDNETCVVQAGENIVLTAELTAENGSVKW---FRD-GVELKDSKKYEMRKDGFSRS 1619

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
              +K  +  +D  +Y  Q  ++  EY  +V
Sbjct: 1620 LVVKATET-KDSGSYSCQTTDDKLEYKVQV 1648



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 63/237 (26%), Positives = 106/237 (44%), Gaps = 15/237 (6%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
           P+ +   K+  V  G+   LS  VVG+P P ITW ++   + +     T  DGD + +TI
Sbjct: 10  PRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTI 69

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
            +   ++D G Y  +A+N+ G A  +  + V  P E     P+F+ +     V   G + 
Sbjct: 70  YE-LTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVV 128

Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
            V RV  +P  +  W ++   +  S  +    D ++  L I  V   +D G Y C A N+
Sbjct: 129 FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGV-RHLDGGTYTCRAQNT 187

Query: 912 AGKSSHGARVTIDVE----------KVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
           AG++   A +T+D +            + + HLQK  E  +    I   + S   S+
Sbjct: 188 AGRAHAAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEESSVTSS 244



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 135/674 (20%), Positives = 276/674 (40%), Gaps = 58/674 (8%)

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108
            W  DG +++   + Y   +      L IR  +   +G     +   S ++    V+ PP 
Sbjct: 650  WSLDGRLLRSGAD-YLITRSKTTHTLLIRCVTAEMDGTVVKFVGGGSQSSCTLSVKAPPV 708

Query: 1109 IITR--LQNQKVNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
              T   +  + V    +AT ++  E++  DA V W ++G E++     +   + +K+ L 
Sbjct: 709  RFTNKSVTLELVTCSAQATAQLTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILL 768

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEIPD 1222
            +++   +D G Y C + +   +  L +++    F    R P  +      D  L+ ++  
Sbjct: 769  VHNVTEEDVGVYECVLADDSMSIQLALKDEPAKFLNKARGPMGLASSLKGDLELSCDVTP 828

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
             +  V W K +  I + ++   IS   +R LIIR   + D+  Y+C     K T ++K++
Sbjct: 829  ASALVVWRKDQVEITEDQRTIFISKGTQRKLIIRNAKKSDEGHYSCETATDKVTFQVKIK 888

Query: 1283 ----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
                +  F  K    ++E +       TL  +  +  +   +W  + K++   +      
Sbjct: 889  ETQSLAAFSHK-ETVQKEVKASVSQKATLSCNV-SDTKTEVKWYKDGKLLISSRTIYSEA 946

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSSS 1396
               +  L I+KVE +DAG Y      +     + +  T     +   +   N + +    
Sbjct: 947  KGNTRQLVIEKVEKSDAGEYTCEAGGDKLVFTITVTGTRTSSTNACVRQIFNTITLFLPP 1006

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKT-NSSYRFRAY 1454
            ++ C+  P     + IIYY +  + I     +      ++ Q++  N ++     + R  
Sbjct: 1007 LHSCFVLP-----AAIIYYAIVNRHIKIEPLVFFCLFPSEAQSAFLNRESVQKEGQSRQL 1061

Query: 1455 AVNEVDISDASE---TTEYYKVIKETKI-QSPTV----EKPLKNITTEPNEDIELTCIFG 1506
             ++  +  DA E    +   K++   ++ ++P+     E   K++    ++   L+C   
Sbjct: 1062 LIDSTERKDAGEYICESGSEKLVFRIQVAEAPSAFFKKESIQKDVKASVSQKAVLSCDVT 1121

Query: 1507 GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
              P+ +V WY+DGK L + +  +                     +   D GE   SC VG
Sbjct: 1122 D-PKTEVKWYKDGKLLTSTRMVH-------VESKGKNRQLVIDSVERKDAGEY--SCEVG 1171

Query: 1567 IQQ---KPVIT-------ISNEDIKQKH-KVGDEWLVTAVIE-GIPPPEVIWYKNGNKLE 1614
            I++   K  +T         N+D  QK  K       +   E      EV WYK+G  L 
Sbjct: 1172 IEKLLFKLHVTDLQVRSAFCNQDSVQKEIKATVSQKASLCCEVSDSKTEVKWYKDGKLLG 1231

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
            + +  +  +K K+ ++ ++ + +  + +Y  E    AGT   ++T K++ + ++ E    
Sbjct: 1232 SSRTIHTESKGKSRLLVVESVDKKDAGEYVCE----AGTE--KLTFKIHVEAARAEVQAK 1285

Query: 1675 MREISRESVTIEWK 1688
               +++ESV  E K
Sbjct: 1286 SAFLNKESVQTEVK 1299



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 113/516 (21%), Positives = 196/516 (37%), Gaps = 33/516 (6%)

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
            K  D G+YT  A N  G   ++ ++TV+EP     + P F  + Q++ V+EK +  L+  
Sbjct: 309  KQSDNGLYTCNAANMAGQTYSAVLVTVKEP-----QVP-FRRKLQDVEVQEKKSAMLMCE 362

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            V         W+     +  S       +G    L I NV +  D G Y C       + 
Sbjct: 363  VPL-VATHTNWFMEETRLEQSSKYHMEQEGTLRRLTIHNVTTN-DDGVYIC-------EM 413

Query: 916  SHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHR 973
              G+R   ++  +    K L +        TVI   +  H      W  N +++      
Sbjct: 414  KEGSRTVAELTVRGNITKKLPRRTVVPISDTVIFCVELEHPCADAYWTRNSEKLKEGSRV 473

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
             I    R            D G +  +  D +TST   V            D  +  K  
Sbjct: 474  SIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVTAARKHPPDSPVDAVIHNKTE 533

Query: 1034 AILEVEINSETADVVWERDGEIIKPKK--NK-YDFEKRGH-IRKLYIRNTSVHDEGEYSC 1089
            + + ++ +   +D      G I++ +K  NK +     G  I    I   S  +E  Y  
Sbjct: 534  SSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQRCNAGETITSTEITLCSFAEEASYQF 593

Query: 1090 ILRDESCTAEVTVVELPP----EIITRLQNQKVNKGNKATFEIELTKGDALV---RWFKD 1142
             +   +   +   +E+P     E +  +    +N    A  E  ++ G + V    W  D
Sbjct: 594  RISAMNDFGQSPYLEVPGSFYLEPLAEVTKGLINSTAVAGEEFSISVGLSAVCSGFWSLD 653

Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEPSINFTLR 1201
            G  ++      +T       L I     +  G     V G S+ +  L+V+ P + FT +
Sbjct: 654  GRLLRSGADYLITRSKTTHTLLIRCVTAEMDGTVVKFVGGGSQSSCTLSVKAPPVRFTNK 713

Query: 1202 --LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
                E +   A   A LT E+ D    V W +    ++  +K+  +S+ +KR L++   T
Sbjct: 714  SVTLELVTCSAQATAQLTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILLVHNVT 773

Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295
            E+D   Y CVL D   + +L ++  + P K ++  R
Sbjct: 774  EEDVGVYECVLADDSMSIQLALK--DEPAKFLNKAR 807



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 61/261 (23%), Positives = 109/261 (41%), Gaps = 8/261 (3%)

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELPPE 1108
            DG  I   +    +E       L +      D G Y+C    +  ++ +A +  V+ P  
Sbjct: 281  DGTNISEGRRHVIYEDHAENFILKVLYCKQSDNGLYTCNAANMAGQTYSAVLVTVKEPQV 340

Query: 1109 IITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
               R LQ+ +V +   A    E+        WF + + ++ S+   +  +G  ++L I++
Sbjct: 341  PFRRKLQDVEVQEKKSAMLMCEVPLVATHTNWFMEETRLEQSSKYHMEQEGTLRRLTIHN 400

Query: 1168 CDLDDAGEYSCEVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
               +D G Y CE+   S+  A LTV     N T +LP   +VP +      VE+     D
Sbjct: 401  VTTNDDGVYICEMKEGSRTVAELTVRG---NITKKLPRRTVVPISDTVIFCVELEHPCAD 457

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
              W +    +++  + ++   +++ TL IR C  DD  E   V  D K++T+  V     
Sbjct: 458  AYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVTAARK 517

Query: 1287 PPKIVDYEREYRIKRGSDVTL 1307
             P     +     K  S +T+
Sbjct: 518  HPPDSPVDAVIHNKTESSITI 538



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 65/220 (29%), Positives = 87/220 (39%), Gaps = 30/220 (13%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G      C V G P P ITW R    +     F+   D D V  L I E+  ED+G + C
Sbjct: 24  GKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGD-VYRLTIYELTLEDSGQYMC 82

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            AKN  G A +   L V  P     +EM                      P F  KP   
Sbjct: 83  RAKNNVGEAYAAVTLKVALP-----AEMPQRA------------------PVFVVKPATA 119

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V  G D++  CR+ A PE +  W   G  +     + +  +SD     S+LKI  V+  
Sbjct: 120 RVGLGGDVVFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSD----SSILKIQGVRHL 175

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
             GTYT  A N  G A     L +    ++   +I+P KS
Sbjct: 176 DGGTYTCRAQNTAGRAHAAAALTVDA--QDSHSLIKPDKS 213



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 64/244 (26%), Positives = 103/244 (42%), Gaps = 13/244 (5%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           L G  P F  +PKA  V  G D  L C +V  P P I W     ++          + D+
Sbjct: 5   LFGGVPRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDV 64

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744
           +     L I  +     G Y   A N  GEA   + LK+    +  ++ P  V++P  + 
Sbjct: 65  YR----LTIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATAR 120

Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEG 801
            V  G  V+   +V  +P     W K+ + + ++   K   D+ S +ILK + V+  D G
Sbjct: 121 -VGLGGDVVFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDS-SILKIQGVRHLDGG 178

Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            YT +A+N+ G A  +A +TV+     +   P           K K  +K    + R+  
Sbjct: 179 TYTCRAQNTAGRAHAAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEE 238

Query: 862 PSIT 865
            S+T
Sbjct: 239 SSVT 242



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 50/187 (26%), Positives = 77/187 (41%), Gaps = 9/187 (4%)

Query: 1200 LRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258
            L  P+   V    DA L+  +    T  +TW + K  +    +F  + D     L I + 
Sbjct: 13   LTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYEL 72

Query: 1259 TEDDQCEYTCVLL----DAKSTTKLKVEV-VEFP---PKIVDYEREYRIKRGSDVTLLVD 1310
            T +D  +Y C       +A +   LKV +  E P   P  V      R+  G DV  +  
Sbjct: 73   TLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVVFVCR 132

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
              A P+ N EW  + + + +    K   DS S+ L I+ V + D G Y  R +N  G A 
Sbjct: 133  VAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNTAGRAH 192

Query: 1371 VEMNVTI 1377
                +T+
Sbjct: 193  AAAALTV 199



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 2/156 (1%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P  +  W +N  KL+     +I    +   + I++ +   S +    A +   ++   VT
Sbjct: 454  PCADAYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVT 513

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
                  P  P   VI  + +  S+TI+W PP  D  + +  Y +E  +  N  W +    
Sbjct: 514  AARKHPPDSPVDAVIHNK-TESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQRCNAG 572

Query: 1720 DRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
            +    T   +    E   Y FR+ A N  G S  LE
Sbjct: 573  ETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLE 608



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 48/193 (24%), Positives = 81/193 (41%), Gaps = 17/193 (8%)

Query: 1016 IPEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
            +P F+ + + F V   KD  +    + S T  + WERD ++      ++   + G + +L
Sbjct: 9    VPRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERD-KLKLTSGGRFKTVEDGDVYRL 67

Query: 1075 YIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEI-------ITRLQNQKVNKGNKA 1124
             I   ++ D G+Y C  ++   E+  A    V LP E+       + +    +V  G   
Sbjct: 68   TIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDV 127

Query: 1125 TFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179
             F   +    +A   W KDG  +  SN +++  D     LKI      D G Y+C     
Sbjct: 128  VFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNT 187

Query: 1180 VGNSKCTAILTVE 1192
             G +   A LTV+
Sbjct: 188  AGRAHAAAALTVD 200



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 81/357 (22%), Positives = 135/357 (37%), Gaps = 23/357 (6%)

Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
           L D   Y    +  + E    + +     +E    AP+FV K        G  V F C+V
Sbjct: 74  LEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVVFVCRV 133

Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             +P     W +    +  S   ++  D D+ + L I+ V   D GT+TC A+N AG A 
Sbjct: 134 AAHPEANFEWEKDGRYLGESNRVKIVSDSDS-SILKIQGVRHLDGGTYTCRAQNTAGRAH 192

Query: 594 STTELIVEAPLS------DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDE 647
           +   L V+A  S      D  + +                I      + +        D 
Sbjct: 193 AAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEESSVTSSSVTSITDG 252

Query: 648 GSDILLECRLVAIPEPDIAWLFKG---EEIVPDENISVA---IESDMHMYCSVLKITNVK 701
              + LE  L A     +A L KG          NIS     +  + H    +LK+   K
Sbjct: 253 LGSLGLEHALRA---STLAMLPKGVFTRTCTDGTNISEGRRHVIYEDHAENFILKVLYCK 309

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           +   G YT  A N  G+    +++ +K  E + P     L+ + V++ +S +L  +V   
Sbjct: 310 QSDNGLYTCNAANMAGQTYSAVLVTVK--EPQVP-FRRKLQDVEVQEKKSAMLMCEVPLV 366

Query: 762 PRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAE 815
              T  + +  +  ++     + +G    +TI       D+GVY  +  E S  +AE
Sbjct: 367 ATHTNWFMEETRLEQSSKYHMEQEGTLRRLTI-HNVTTNDDGVYICEMKEGSRTVAE 422



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 3/87 (3%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-- 1922
            PP  P + V+   T  S+T++W+ P+S+   PI  YI+E + V  K+W +    G ++  
Sbjct: 519  PPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQR-CNAGETITS 577

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVS 1949
             E  + +  E+    FRISA N  G S
Sbjct: 578  TEITLCSFAEEASYQFRISAMNDFGQS 604



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 41/177 (23%), Positives = 68/177 (38%), Gaps = 13/177 (7%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX--YKCIA 1552
            +D  L+C   G P P +TW RD  KL +     T E+                  Y C A
Sbjct: 25   KDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYELTLEDSGQYMCRA 84

Query: 1553 FNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
             N+ GE   +  + +       Q+ PV  +  +    +  +G + +    +   P     
Sbjct: 85   KNNVGEAYAAVTLKVALPAEMPQRAPVFVV--KPATARVGLGGDVVFVCRVAAHPEANFE 142

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            W K+G  L       I +   +S+++I+ ++      YT  A NTAG +     L V
Sbjct: 143  WEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNTAGRAHAAAALTV 199



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 41/174 (23%), Positives = 68/174 (39%), Gaps = 13/174 (7%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  +TR +   V  G  AT    +      L+ W +D  ++      +   DG   +L I
Sbjct: 10   PRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTI 69

Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI- 1220
            Y+  L+D+G+Y C     VG +     L V  P+     R P F++ PA     L  ++ 
Sbjct: 70   YELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPA-EMPQRAPVFVVKPATARVGLGGDVV 128

Query: 1221 ------PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
                       +  W K    + ++ +  ++SD     L I+     D   YTC
Sbjct: 129  FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTC 182



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 3/111 (2%)

Query: 1956 SVRLEKHATVPSPPTAPLE--IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
            S R    A    PP +P++  I     + +   W  P+ D   P+ GY +  R V    W
Sbjct: 507  STRFTVTAARKHPPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTW 566

Query: 2014 MEVGKVD-VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
                  + + + +  +   +E  +Y  RI A N+ G S  LE    F + P
Sbjct: 567  QRCNAGETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLEVPGSFYLEP 617



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 1/91 (1%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            VG +  ++  + G P P + W ++  KL +   +          + I EL    S +Y  
Sbjct: 23   VGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYELTLEDSGQYMC 82

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPE-GPVIM 1675
             A N  G +   VTLKV      P+  PV +
Sbjct: 83   RAKNNVGEAYAAVTLKVALPAEMPQRAPVFV 113



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            V F+C+V      ++ WF+    +KP +   ++       TLVI +  PEDAGT+ C
Sbjct: 2027 VTFDCEVSR-TNTEVKWFKDNVELKPGKMVGIH-SLGRKRTLVINKCTPEDAGTYIC 2081


>UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB;
            n=1; Apis mellifera|Rep: PREDICTED: similar to CG33519-PB
            - Apis mellifera
          Length = 1306

 Score =  162 bits (393), Expect = 1e-37
 Identities = 187/795 (23%), Positives = 338/795 (42%), Gaps = 77/795 (9%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPD-IAWLFKGEEIVPDENISVAIESDMHMYC 692
            P F K  +   V+ G   + EC L+       + WL   + +  ++ ++  + +      
Sbjct: 479  PVFVKTLEGSSVEPGEMAVFECTLLYTDSTTRVQWLKDNKPL--EDRLADRLTASATGKT 536

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEKEP------PQVIEPLKS 743
              L + NV +   G Y   A+N EG+++     IV ++   EK+       P  +  LK 
Sbjct: 537  FRLTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKD 596

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSITILKPKK 796
              + +   +    +V G+P P + + K+N         VK +  + D   + + IL+  +
Sbjct: 597  TELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVKIVTEQGDKGFYEL-ILEDVQ 655

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             +D G Y+  A+N  G     A +TV +      E  L++         E G        
Sbjct: 656  KQDAGKYSCTAKNKFGETSCEASVTVSD------EKMLYLPE----DFLEPGM------- 698

Query: 857  TRNPVPSITWYRNNEIISPSETITQNF-DGEN-IELVITNVDSEIDSGDYKCVASNSAGK 914
                 P  TW R+ +   P E     F D E+ + LV  +V  E D+G Y CVA  S G 
Sbjct: 699  ----EPRFTWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPE-DAGLYTCVAQTSTGN 753

Query: 915  SSHGARVTI---------DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHN 963
             S  A +T+         D E+       + S E   G + +LE Q         KW  +
Sbjct: 754  ISCSAELTVQGAVNQLLKDPERPKLCSEAKHS-EVSAGGSAMLELQIRGYPKPDIKWTKD 812

Query: 964  KKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEF 1019
             +EI +G  ++ + ++              D GV     K++   +T+ + ++ ++ P+ 
Sbjct: 813  GQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIELIVKSAPKI 872

Query: 1020 IRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGH-IRKLYIR 1077
             R+  D      +   + VEI +  A +V W +DG+ IK + N+   E+ G+   KL I+
Sbjct: 873  TRRQTDTTCIVDETLTMTVEIEATPAPEVKWYKDGQEIK-ENNRITIEREGNETYKLTIK 931

Query: 1078 NTSVHDEGEYSCILRDE-SCTAEVTVVEL--PPEIITRLQNQKV-NKGNKATFEIELTKG 1133
            N  + D G YS + R+E + T E+  +++  PP I   L    + ++G      +E+   
Sbjct: 932  NARLDDTGSYSIVARNEVNQTTEIWKLKVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSV 991

Query: 1134 -DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--GNSKCTAILT 1190
                ++W++DG  +   N I++T +G +  L+I +   +DAG Y  E+   +   T    
Sbjct: 992  MPPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKAEITSDHGVVTDQTR 1051

Query: 1191 VEEPSI-NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWY-KKKSVIEDTEKFTLISD 1247
            +    I  F  ++ +  +     D    VEI       + WY     + E  ++F    +
Sbjct: 1052 IRVKGIPRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEE 1111

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVT 1306
             +  TLII +   + +  YTC L +     K     +V   P+++    + RIK G  + 
Sbjct: 1112 EESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRPRLLKKLADQRIKEGDTLK 1171

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIK---KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            L+ +    P P  +W  + + +    + K T+ S   ++  LT+  V+ +DAGIY++R E
Sbjct: 1172 LIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKGSDAGIYEVRAE 1231

Query: 1364 NNCGHADVEMNVTIL 1378
            N  G    +  V I+
Sbjct: 1232 NELGFVTSKSKVLIM 1246



 Score =  132 bits (319), Expect = 1e-28
 Identities = 131/531 (24%), Positives = 222/531 (41%), Gaps = 54/531 (10%)

Query: 539  PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
            P+ TW R      P + F++ + D+++   LV + V PEDAG +TCVA+ + G  S + E
Sbjct: 700  PRFTWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAE 759

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            L V+  ++                      + +   P    + K   V  G   +LE ++
Sbjct: 760  LTVQGAVNQL--------------------LKDPERPKLCSEAKHSEVSAGGSAMLELQI 799

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
               P+PDI W   G+EIV         E +  M    L I NV     G YT+ A N  G
Sbjct: 800  RGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESM---SLVIKNVTAKDAGVYTIRAKNELG 856

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK- 776
            E +  I L +K+     P++            E++ ++ ++   P P + W K+ + +K 
Sbjct: 857  EDTTQIELIVKSA----PKITRRQTDTTCIVDETLTMTVEIEATPAPEVKWYKDGQEIKE 912

Query: 777  --ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
               +  + +G +T+ +TI K  ++ D G Y++ A N   + +T+ +  ++        PP
Sbjct: 913  NNRITIEREGNETYKLTI-KNARLDDTGSYSIVARNE--VNQTTEIWKLKV-----LSPP 964

Query: 834  LFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
                   E  + ++G  + L   V     PSI WYR+ E +     I    +G    L I
Sbjct: 965  RIRKGLGEPVIIDQGANLVLTVEVDSVMPPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRI 1024

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI---LE 949
             N  SE D+G YK   ++  G  +   R  I V+ +   K         EG   I   +E
Sbjct: 1025 VNTVSE-DAGFYKAEITSDHGVVTDQTR--IRVKGIPRFKTKMYDVTVNEGTKDIEFKVE 1081

Query: 950  CQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQ---- 1004
                   S  WY +  EI+      + +E              ++ G   C +K++    
Sbjct: 1082 IDGCPQPSIHWYIDDVEITEKRKEFVRKEEEESCTLIISEAKTELKGRYTCKLKNEFGEV 1141

Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054
            ++S+ L+V    P  ++KL D  +KE D   L  E+  +    V W +DG+
Sbjct: 1142 KSSSTLIVNSR-PRLLKKLADQRIKEGDTLKLIFEVAGTPDPQVKWYKDGQ 1191



 Score =  131 bits (317), Expect = 2e-28
 Identities = 162/703 (23%), Positives = 290/703 (41%), Gaps = 81/703 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPK-KNKYDFEKRGHIRK 1073
            P F++ L+   V+  ++A+ E  +     T  V W +D + ++ +  ++      G   +
Sbjct: 479  PVFVKTLEGSSVEPGEMAVFECTLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKTFR 538

Query: 1074 LYIRNTSVHDEGEYSC-ILRDE---SCTAEVTVVELPPE------------IITRLQNQK 1117
            L ++N    D G Y    +  E   +CTA++ V +L PE             + RL++ +
Sbjct: 539  LTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKDTE 598

Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI---DGKK--QKLKIYDCDL 1170
            + +     F +++ KGD    ++++KD   I  SNH ++ I    G K   +L + D   
Sbjct: 599  LMENTYLRFMVKV-KGDPNPEMKFYKDNVLID-SNHPRVKIVTEQGDKGFYELILEDVQK 656

Query: 1171 DDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
             DAG+YSC    + G + C A +TV +  +   L LPE  L P     +           
Sbjct: 657  QDAGKYSCTAKNKFGETSCEASVTVSDEKM---LYLPEDFLEPGMEPRF----------- 702

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTL--IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV- 1283
             TW +     +  E+F ++    + TL  + +    +D   YTCV   +        E+ 
Sbjct: 703  -TWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAELT 761

Query: 1284 --------VEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCK 1332
                    ++ P  PK+    +   +  G    L +  + +P+P+ +W  + + I+   K
Sbjct: 762  VQGAVNQLLKDPERPKLCSEAKHSEVSAGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGK 821

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
            +     D +S SL IK V   DAG+Y +R +N  G    ++ + +   P    +      
Sbjct: 822  YKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIELIVKSAPKITRRQTDTTC 881

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYR 1450
                      E E T    + +Y  + QEI     I+++       + +I+N + + +  
Sbjct: 882  IVDETLTMTVEIEATPAPEVKWYK-DGQEIKENNRITIEREGNETYKLTIKNARLDDTGS 940

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVP 1509
            +   A NEV+     +TTE +K+     +  P + K L + +  +   ++ LT     V 
Sbjct: 941  YSIVARNEVN-----QTTEIWKL---KVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSVM 992

Query: 1510 QPKVTWYRDGKKL---KTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P + WYRDG+ +      K T E NR               YK    +DHG V     +
Sbjct: 993  PPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKAEITSDHGVVTDQTRI 1052

Query: 1566 GIQQKPVITISNEDIKQKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITT 1623
             ++  P       D+       D E+ V   I+G P P + WY +  ++ E  KE+    
Sbjct: 1053 RVKGIPRFKTKMYDVTVNEGTKDIEFKVE--IDGCPQPSIHWYIDDVEITEKRKEFVRKE 1110

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +E++  + I E K     +YT +  N  G      TL V  +P
Sbjct: 1111 EEESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRP 1153



 Score =  116 bits (279), Expect = 7e-24
 Identities = 183/846 (21%), Positives = 329/846 (38%), Gaps = 95/846 (11%)

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVE 926
            S S  + + +   +   + T+   E  S   K  AS+    +S   R ++        + 
Sbjct: 418  SSSSKVVEEYSSVSSSQIGTSTYVESSSSAVKMEASSYQAGNSIETRTSMAKIEGGGGIG 477

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVST---KWYHNKKEISGM--DHREIIQEGRX 981
            K  FVK L+ S   E G+  + EC   +T ST   +W  + K +     D       G+ 
Sbjct: 478  KPVFVKTLEGS-SVEPGEMAVFECTLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKT 536

Query: 982  XXXXXXXXXXXDVGV-IKCIVKDQETST---MLVVKETIPE------------FIRKLQD 1025
                       D G+ I   +  +  ST    L+V++  PE            F+ +L+D
Sbjct: 537  FRLTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKD 596

Query: 1026 FEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDF-EKRGH--IRKLYIRNTSV 1081
             E+ E       V++  +   ++ + +D  +I     +     ++G     +L + +   
Sbjct: 597  TELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVKIVTEQGDKGFYELILEDVQK 656

Query: 1082 HDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
             D G+YSC  +++    SC A VTV +   E +  L    +  G +  F           
Sbjct: 657  QDAGKYSCTAKNKFGETSCEASVTVSD---EKMLYLPEDFLEPGMEPRFT---------- 703

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL--DDAGEYSC----EVGNSKCTAILTV 1191
             W +DG         ++     +  L +    +  +DAG Y+C      GN  C+A LTV
Sbjct: 704  -WLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAELTV 762

Query: 1192 EEPSINFTLRLPE---------FILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEK 1241
            +  ++N  L+ PE            V A   A L ++I      D+ W K    I    K
Sbjct: 763  QG-AVNQLLKDPERPKLCSEAKHSEVSAGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGK 821

Query: 1242 FTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYR 1298
            +  +  D +  +L+I+  T  D   YT    +   + TT++++ +V+  PKI   + +  
Sbjct: 822  YKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIEL-IVKSAPKITRRQTDTT 880

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH-TKPSIDSKSASLTIKKVENTDAGI 1357
                  +T+ V+ +A P P  +W  + + IK+    T     +++  LTIK     D G 
Sbjct: 881  CIVDETLTMTVEIEATPAPEVKWYKDGQEIKENNRITIEREGNETYKLTIKNARLDDTGS 940

Query: 1358 YKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            Y +   N          + +L  P    G    + ID  +  +   E ++    +I +Y 
Sbjct: 941  YSIVARNEVNQTTEIWKLKVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSVMPPSIKWYR 1000

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
                 ++       K   +    I N  +  +  ++A    E+  SD    T+  ++   
Sbjct: 1001 DGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKA----EIT-SDHGVVTDQTRI--- 1052

Query: 1477 TKIQS-PTVEKPLKNITT-EPNEDIELTCIFGGVPQPKVTWYRDG-----KKLKTAKATY 1529
             +++  P  +  + ++T  E  +DIE      G PQP + WY D      K+ +  +   
Sbjct: 1053 -RVKGIPRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEE 1111

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589
            E                 Y C   N+ GEV++S  + +  +P +     D  Q+ K GD 
Sbjct: 1112 EESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRPRLLKKLAD--QRIKEGDT 1169

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHSSKYTIE 1646
              +   + G P P+V WYK+G ++  D    IT   K      + +  +K S +  Y + 
Sbjct: 1170 LKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKGSDAGIYEVR 1229

Query: 1647 ASNTAG 1652
            A N  G
Sbjct: 1230 AENELG 1235



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 111/502 (22%), Positives = 186/502 (37%), Gaps = 47/502 (9%)

Query: 1217 TVEIPDETLDVTWYKKKSVIED--TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
            T+   D T  V W K    +ED   ++ T  +  K   L ++   E D   Y    ++++
Sbjct: 501  TLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKTFRLTLQNVLESDSGIYIARAMNSE 560

Query: 1275 --STTKLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVD-YQAFP-----QPNDEW- 1321
              ST   ++ V +  P+      E      + R  D  L+ + Y  F       PN E  
Sbjct: 561  GQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKDTELMENTYLRFMVKVKGDPNPEMK 620

Query: 1322 IVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
                 ++    H +  I     D     L ++ V+  DAG Y    +N  G    E +VT
Sbjct: 621  FYKDNVLIDSNHPRVKIVTEQGDKGFYELILEDVQKQDAGKYSCTAKNKFGETSCEASVT 680

Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
            + D+       + LE         W       +    + V+     DT   +        
Sbjct: 681  VSDEKMLYLPEDFLE-PGMEPRFTWLRDGKPFDPEERFKVLFKDNEDTLALV-------- 731

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKI-QSPTVEKPLKNITTE 1494
                Q++K   +  +   A     +IS ++E T    V +  K  + P +    K+    
Sbjct: 732  ---FQHVKPEDAGLYTCVAQTSTGNISCSAELTVQGAVNQLLKDPERPKLCSEAKHSEVS 788

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY----ENRXXXXXXXXXXXXXXXYK 1549
                  L     G P+P + W +DG+++    K  Y    E                 Y 
Sbjct: 789  AGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYT 848

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYK 1608
              A N+ GE  T   + ++  P IT    D      + DE L +T  IE  P PEV WYK
Sbjct: 849  IRAKNELGEDTTQIELIVKSAPKITRRQTDTTC---IVDETLTMTVEIEATPAPEVKWYK 905

Query: 1609 NGNKLENDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +G +++ +    I  +  +T  + IK  +   +  Y+I A N    ++    LKV   P 
Sbjct: 906  DGQEIKENNRITIEREGNETYKLTIKNARLDDTGSYSIVARNEVNQTTEIWKLKVLSPPR 965

Query: 1668 KPEG---PVIMREISRESVTIE 1686
              +G   PVI+ + +   +T+E
Sbjct: 966  IRKGLGEPVIIDQGANLVLTVE 987



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 16/201 (7%)

Query: 629  LEGIPPTFSKKPKAQYVDEGS-DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++GIP  F  K     V+EG+ DI  +  +   P+P I W     EI   E     +  +
Sbjct: 1054 VKGIP-RFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEIT--EKRKEFVRKE 1110

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                C+++ I+  K   +G YT    N  GE      L + +     P++++ L    ++
Sbjct: 1111 EEESCTLI-ISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNS----RPRLLKKLADQRIK 1165

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG---DTHSITILKPKKVKDEG 801
            +G+++ L  +V G P P + W K+ + V A   +    D    + + +T+   K   D G
Sbjct: 1166 EGDTLKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKG-SDAG 1224

Query: 802  VYTLKAENSEGIAETSAVITV 822
            +Y ++AEN  G   + + + +
Sbjct: 1225 IYEVRAENELGFVTSKSKVLI 1245



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 27/79 (34%), Positives = 44/79 (55%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G +   E Q+ GYP+P I W +    I     ++  ++D+   +LVI+ V  +DAG +T 
Sbjct: 790 GGSAMLELQIRGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYTI 849

Query: 584 VAKNAAGFASSTTELIVEA 602
            AKN  G  ++  ELIV++
Sbjct: 850 RAKNELGEDTTQIELIVKS 868



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 3/105 (2%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII---KPSQD 555
           E+  +  ++ APIF+ +L+     + + ++F  +V+G P P++ +++   +I    P   
Sbjct: 577 EEKKARAEANAPIFLVRLKDTELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVK 636

Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                 D     L++ +V  +DAG ++C AKN  G  S    + V
Sbjct: 637 IVTEQGDKGFYELILEDVQKQDAGKYSCTAKNKFGETSCEASVTV 681



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 510  PIFVEKLRPKHTPDGST-VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            P F  K+      +G+  ++F+ +++G P+P I W+     I   +   +  +++   TL
Sbjct: 1058 PRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEEEESCTL 1117

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            +I E   E  G +TC  KN  G   S++ LIV +
Sbjct: 1118 IISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNS 1151



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-- 567
            P  ++KL  +   +G T++   +V G P PQ+ W++    +      ++  D        
Sbjct: 1153 PRLLKKLADQRIKEGDTLKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYD 1212

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            L +  V   DAG +   A+N  GF +S +++++
Sbjct: 1213 LTVTLVKGSDAGIYEVRAENELGFVTSKSKVLI 1245



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 17/78 (21%), Positives = 37/78 (47%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           T+    ++E  P P++ W++    IK +    +  + +    L I+    +D G+++ VA
Sbjct: 886 TLTMTVEIEATPAPEVKWYKDGQEIKENNRITIEREGNETYKLTIKNARLDDTGSYSIVA 945

Query: 586 KNAAGFASSTTELIVEAP 603
           +N     +   +L V +P
Sbjct: 946 RNEVNQTTEIWKLKVLSP 963


>UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and
            spectrin domains 1; n=3; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to SEC14 and spectrin
            domains 1 - Strongylocentrotus purpuratus
          Length = 3464

 Score =  159 bits (387), Expect = 6e-37
 Identities = 117/466 (25%), Positives = 203/466 (43%), Gaps = 19/466 (4%)

Query: 465  EKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG 524
            EK     + +  E+  TQ  +K+  E     P  E    +    AP F  K+R      G
Sbjct: 2377 EKSTKSIKLVQPESPITQ-TRKEPVEAFLTFPAPEPEPPKPVGYAPYFTRKIRDNLVKQG 2435

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
               Q +C V+G P P++ WF+    ++ S + ++   D  +  L      PE AG ++  
Sbjct: 2436 RATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGICALSFYNTQPEAAGVYSIK 2495

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            A N  G A    EL V+A   +      V                    P F + P  + 
Sbjct: 2496 AFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKLTH----NATMPKFIEIPGDKN 2551

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V+EG  ++LE  + A P+P++ W   G + V  E   + ++   H     L I       
Sbjct: 2552 VEEGKPLILEVTVDAYPQPNVVWSKDGIK-VKGEPYILKVDKKTH----TLIIPEADLED 2606

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            EG +   A N  G A   I +K+   E EPP  + PL +   ++G        + G+P P
Sbjct: 2607 EGIFICTATNPAGRAECIIQVKVNEAE-EPPVFLTPLVNAQAKKGTPFAFECVLKGDPVP 2665

Query: 765  TITWCKNNKPVKA----LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818
             + W KNNKPVK        K + +T  +  L+  +V  +D   Y+ +A N  G AET+ 
Sbjct: 2666 VVEWLKNNKPVKEENPDYNLKRNTET-GVCRLEIDEVFPEDAARYSCRATNEAGKAETTC 2724

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            +++V    +++   P+ I+  +++T++E   I+L  ++      S+ W++ +E +  +  
Sbjct: 2725 MLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGE 2784

Query: 879  ITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
                FD  E + ++  N     D G Y C A+N+ G+++  A + +
Sbjct: 2785 FLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIV 2830



 Score =  122 bits (295), Expect = 8e-26
 Identities = 173/818 (21%), Positives = 306/818 (37%), Gaps = 99/818 (12%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+E    K+  +G  +  E  V+ YP+P + W +    IK   +  +   D    TL+
Sbjct: 2541 PKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDG--IKVKGEPYILKVDKKTHTLI 2598

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I E   ED G F C A N AG A    E I++  +++                       
Sbjct: 2599 IPEADLEDEGIFICTATNPAGRA----ECIIQVKVNEAEE-------------------- 2634

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
               PP F          +G+    EC L   P P + WL K  + V +EN    ++ +  
Sbjct: 2635 ---PPVFLTPLVNAQAKKGTPFAFECVLKGDPVPVVEWL-KNNKPVKEENPDYNLKRNTE 2690

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIV 746
                 L+I  V       Y+  A N  G+A    +L +      +   P +I   + M +
Sbjct: 2691 TGVCRLEIDEVFPEDAARYSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTL 2750

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802
            ++G+ + L+ Q+ G    ++ W K ++ +    + L T  D +  ++  +     +DEGV
Sbjct: 2751 QEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGV 2810

Query: 803  YTLKAENSEGIAETSA---VITVEEPTEENA-------EPPLFINRFQEITVKEKGTIKL 852
            YT +A N+ G   +SA   V+T  +  +  A       E    +++ + +TV+E    KL
Sbjct: 2811 YTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKL 2870

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
               V      +  WY+  E +         F   N+  +  N     DSG Y C  +N+ 
Sbjct: 2871 ACVVDGIAPITAQWYKGEEALDEGYEYVMKFQS-NMATLHVNESFPEDSGMYTCRVTNAI 2929

Query: 913  GKSSHGARVTIDVEKVTFVKHLQ------KSYETEEGKTVILECQTSHT--VSTKWYHNK 964
            G     A+VT+  +       +Q       S E   G+ + L  + S     +  W+H+ 
Sbjct: 2930 GSDESSAQVTVLEDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDD 2989

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPE 1018
            + +      ++++E              D G      +++       T   LV+KE  PE
Sbjct: 2990 RPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYTIRAENESGHESSSTDYKLVIKEAKPE 3049

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
            +          +K      +EI     DVV       + P K +  F     ++  +   
Sbjct: 3050 YAGTYTVVAENDKGQESTSIEI-----DVVPPETQMEVVPVKAEPAF---APLQSRFFTQ 3101

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPP-EIITRLQNQKVNKGNKATFEIELTKGDALV 1137
                     +   R +S   ++ V E  P EI  R+  Q   +                +
Sbjct: 3102 PDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPR----------------I 3145

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE- 1192
             W+KD   I      +++      +L + +  L+D G Y C+     G    T  +TV  
Sbjct: 3146 TWYKDDEPINGKPQYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNV 3205

Query: 1193 ----EPSINFTLRLPEF--ILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLI 1245
                 P+ +      +F  + +P      L   I  +    VTW +    I +TE+  +I
Sbjct: 3206 NAALTPAPHVVPLQTQFSHLDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEII 3265

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
             +    TL+I+    D   +YT V  + + T  + + +
Sbjct: 3266 KEETVHTLVIKNPRPDAGGKYTVVAENERGTETVNIVI 3303



 Score =  113 bits (272), Expect = 5e-23
 Identities = 236/1116 (21%), Positives = 409/1116 (36%), Gaps = 156/1116 (13%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G  P F++K +   V +G    L+C +   P P++ W   G  +    N+ V  E     
Sbjct: 2418 GYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRV--ECGDAG 2475

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEAS---------------LPI-VLKIKTGEKE- 733
             C+ L   N +    G Y++ A N  GEA                LP  V K+ TG  + 
Sbjct: 2476 ICA-LSFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKL 2534

Query: 734  -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDT 786
                  P+ IE      V +G+ +IL   V   P+P + W K+   VK  P   K D  T
Sbjct: 2535 THNATMPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPYILKVDKKT 2594

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
            H++ I+    ++DEG++   A N  G AE   +I V+    E  EPP+F+        K+
Sbjct: 2595 HTL-IIPEADLEDEGIFICTATNPAGRAE--CIIQVK--VNEAEEPPVFLTPLVNAQAKK 2649

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEII---SPSETITQNFDGENIELVITNVDSEIDSGD 903
                     +  +PVP + W +NN+ +   +P   + +N +     L I  V  E D+  
Sbjct: 2650 GTPFAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPE-DAAR 2708

Query: 904  YKCVASNSAGKSSHGARVTI------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTV- 956
            Y C A+N AGK+     +++      D+     + H  +    +EG  + L CQ    + 
Sbjct: 2709 YSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISH-PEDMTLQEGDPIRLTCQIGGELP 2767

Query: 957  -STKWYHNKKEISGMDHR-EII-----QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----E 1005
             S  W+   KE   +D   E +     QEG             D GV  C   +      
Sbjct: 2768 LSVNWF---KEDEALDEAGEFLMTFDDQEG-LAVLKVNESFAEDEGVYTCQATNAWGRTA 2823

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE----VEINS----ETADVV--------- 1048
            +S  L+V   + E      D   K +   IL     V +      + A VV         
Sbjct: 2824 SSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQ 2883

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV 1103
            W + GE    +  +Y  + + ++  L++  +   D G Y+C     I  DES +A+VTV+
Sbjct: 2884 WYK-GEEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDES-SAQVTVL 2941

Query: 1104 ELPPEIITRLQNQKVNKGN---------KATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154
            E        +Q  K+   +         K  F++     +  V W  D   ++    I++
Sbjct: 2942 EDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVS-GNPEPTVTWHHDDRPLRPDGRIKV 3000

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
              +     ++I   + DD G+Y+    N         E  S ++ L + E    P     
Sbjct: 3001 VKEDTTYTMQISRSEPDDTGKYTIRAENESGH-----ESSSTDYKLVIKE--AKPEYAGT 3053

Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
            Y  V   D+  + T  +   V  +T  E   + ++     L  R  T+ D          
Sbjct: 3054 YTVVAENDKGQESTSIEIDVVPPETQMEVVPVKAEPAFAPLQSRFFTQPDA--------- 3104

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
                  + V     PP+     ++  +  G  + + +     P P   W  + + I    
Sbjct: 3105 ------MPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKP 3158

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
              + S     A L +++    D G Y  +  N  G       +T+    +    P+++ +
Sbjct: 3159 QYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPL 3218

Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
             +   ++  D P   G    +++ +  Q      W+        Q  ++ ++T      +
Sbjct: 3219 QTQFSHL--DIP--VGQPIRLHFRIRGQPPPKVTWL--------QNDVEIVETEEVEIIK 3266

Query: 1453 AYAVNEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP-Q 1510
               V+ + I +   +    Y V+ E +  + TV     NI    +    +   F   P Q
Sbjct: 3267 EETVHTLVIKNPRPDAGGKYTVVAENERGTETV-----NIVINVSG---VQWFFNNTPIQ 3318

Query: 1511 P--KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI- 1567
            P  +V + RDG         Y                  Y+C A  +   V T C + + 
Sbjct: 3319 PSDRVEFVRDGD-------VY----YLVIKRPTSGDAGLYQCRAETEVSVVTTECTIMVN 3367

Query: 1568 -QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
             +Q P      E +      G    +   + G P P V W K+   +         T+  
Sbjct: 3368 DKQSPDFIAPLESVVASE--GSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGD 3425

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
              ++ I +++ S +  Y I  +N  G S    TL +
Sbjct: 3426 RQILMIIQVRPSDAGNYRITLTNDFGVSVSSATLLI 3461



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 130/633 (20%), Positives = 240/633 (37%), Gaps = 73/633 (11%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI-DGKKQKL 1163
            P    ++++  V +G     +  + KGD    V WFKDG  ++ SN++++   D     L
Sbjct: 2421 PYFTRKIRDNLVKQGRATQLDC-VVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGICAL 2479

Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTL------------------R 1201
              Y+   + AG YS +    +G + C A L V+     F L                   
Sbjct: 2480 SFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKLTHNAT 2539

Query: 1202 LPEFILVPANTDAY----LTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
            +P+FI +P + +      L +E+  +     +V W K    ++  E + L  D K  TLI
Sbjct: 2540 MPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKG-EPYILKVDKKTHTLI 2598

Query: 1255 IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            I +   +D+  + C   +    A+   ++KV   E PP  +      + K+G+       
Sbjct: 2599 IPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTPFAFECV 2658

Query: 1311 YQAFPQPNDEWIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             +  P P  EW+ N+K +K+     + K + ++    L I +V   DA  Y  R  N  G
Sbjct: 2659 LKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCRATNEAG 2718

Query: 1368 HADVE--MNVTILDKP--------SPPGKPNILEID----------SSSINICWDEPENT 1407
             A+    ++V  LD          S P    + E D             +++ W + E+ 
Sbjct: 2719 KAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFK-EDE 2777

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
                   +++ + + +    + V         +   +  +++   A + N + ++   E 
Sbjct: 2778 ALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIVVTAVDEI 2837

Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----K 1523
                  +   K ++  +   L+N+T +     +L C+  G+      WY+  + L    +
Sbjct: 2838 DAAAADVSP-KHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEEALDEGYE 2896

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT------ISN 1577
                   N                Y C   N  G  E+S  V + +    T      +  
Sbjct: 2897 YVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPTAPWIQPLKL 2956

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
            E    +  VG    +   + G P P V W+ +   L  D    +  ++ T  ++I   + 
Sbjct: 2957 ESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTMQISRSEP 3016

Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
              + KYTI A N +G  S     K+  K +KPE
Sbjct: 3017 DDTGKYTIRAENESGHESSSTDYKLVIKEAKPE 3049



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 26/221 (11%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            +M P F  +L+     +G  ++   +V G P P+ITW++    I     ++M +  ++VA
Sbjct: 3111 AMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQYEMSF-VESVA 3169

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
             L +RE F ED G + C A N AG  ++T ++ V                         A
Sbjct: 3170 RLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNV-----------------NAALTPA 3212

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
              +  +   FS       +  G  I L  R+   P P + WL    EIV  E + +  E 
Sbjct: 3213 PHVVPLQTQFSHLD----IPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEE 3268

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
             +H     L I N +    G YTVVA N  G  ++ IV+ +
Sbjct: 3269 TVH----TLVIKNPRPDAGGKYTVVAENERGTETVNIVINV 3305



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 26/273 (9%)

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG-----SEMTVXXXXXXXXX 622
            LVI+E  PE AGT+T VA+N  G  S++ E+ V  P +        +E            
Sbjct: 3041 LVIKEAKPEYAGTYTVVAENDKGQESTSIEIDVVPPETQMEVVPVKAEPAFAPLQSRFFT 3100

Query: 623  XXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
               A  + G  +PP F  + K   V EG  I +  R+   P P I W +K      DE I
Sbjct: 3101 QPDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITW-YK-----DDEPI 3154

Query: 681  SVAIESDMHMYCSVLKITNVKKF--QEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQ 736
            +   + +M    SV ++   + F   EG Y   A N  G+   +  I + +       P 
Sbjct: 3155 NGKPQYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPH 3214

Query: 737  VIEPLKSMI----VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789
            V+ PL++      +  G+ + L  ++ G P P +TW +N+  +   + +    +   H++
Sbjct: 3215 VV-PLQTQFSHLDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEETVHTL 3273

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             I  P+     G YT+ AEN  G    + VI V
Sbjct: 3274 VIKNPRP-DAGGKYTVVAENERGTETVNIVINV 3305



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 11/186 (5%)

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK 798
            K  +V + E    +  +V N    + W  NN P++    +    DGD + + I +P    
Sbjct: 3285 KYTVVAENERGTETVNIVINVSG-VQWFFNNTPIQPSDRVEFVRDGDVYYLVIKRPTS-G 3342

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            D G+Y  +AE    +  T   I V +      + P FI   + +   E  TI+L  R++ 
Sbjct: 3343 DAGLYQCRAETEVSVVTTECTIMVNDK-----QSPDFIAPLESVVASEGSTIRLECRMSG 3397

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            +P P++ W ++   I+ +  +    +G+   L+I  V    D+G+Y+   +N  G S   
Sbjct: 3398 SPAPTVKWTKDERSITETSRVRFLTEGDRQILMIIQVRPS-DAGNYRITLTNDFGVSVSS 3456

Query: 919  ARVTID 924
            A + ID
Sbjct: 3457 ATLLID 3462



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 91/420 (21%), Positives = 158/420 (37%), Gaps = 46/420 (10%)

Query: 1287 PPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI- 1338
            PPK V Y        R+  +K+G    L    +  P P  EW  +   ++   + +    
Sbjct: 2413 PPKPVGYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECG 2472

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVT------ILDKPSPPGKPNIL 1390
            D+   +L+    +   AG+Y ++  N  G A    E++V       +L K  P      +
Sbjct: 2473 DAGICALSFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHI 2532

Query: 1391 EIDSSS-----INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL-- 1443
            ++  ++     I I  D+    G   I+   V+        W       K +  I  +  
Sbjct: 2533 KLTHNATMPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPYILKVDK 2592

Query: 1444 KTNSSYRFRAYAVNE-VDISDASETTEYYKVIKETKI----QSPTVEKPLKNITTEPNED 1498
            KT++     A   +E + I  A+      + I + K+    + P    PL N   +    
Sbjct: 2593 KTHTLIIPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTP 2652

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX-------XXXXXXXXXXYKCI 1551
                C+  G P P V W ++ K +K     Y  +                      Y C 
Sbjct: 2653 FAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCR 2712

Query: 1552 AFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
            A N+ G+ ET+C++ +        + PVI    ED+  +   GD   +T  I G  P  V
Sbjct: 2713 ATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQE--GDPIRLTCQIGGELPLSV 2770

Query: 1605 IWYKNGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             W+K    L+   E+ +T   +E  +V+++ E        YT +A+N  G ++    L V
Sbjct: 2771 NWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIV 2830



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 36/170 (21%), Positives = 76/170 (44%), Gaps = 12/170 (7%)

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            + I    + W F    I P + +    + D++          +K+   G   +     E 
Sbjct: 3301 IVINVSGVQWFFNNTPIQPSDRVEFVRDGDVYYLV-------IKRPTSGDAGLYQCRAET 3353

Query: 718  EASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV- 775
            E S+      I   +K+ P  I PL+S++  +G ++ L  ++ G+P PT+ W K+ + + 
Sbjct: 3354 EVSVVTTECTIMVNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSIT 3413

Query: 776  --KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
                +   ++GD   + I++ +   D G Y +   N  G++ +SA + ++
Sbjct: 3414 ETSRVRFLTEGDRQILMIIQVRP-SDAGNYRITLTNDFGVSVSSATLLID 3462



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 28/243 (11%)

Query: 492  IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
            +D++       S +   A I + KL      +G+  +  C V+G       W++    + 
Sbjct: 2834 VDEIDAAAADVSPKHEAACI-LSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEEALD 2892

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
               ++ M +   N+ATL + E FPED+G +TC   NA G   S+ ++ V   L D  S  
Sbjct: 2893 EGYEYVMKFQS-NMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTV---LED--SSP 2946

Query: 612  TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671
            T              +I  G P                 I L  ++   PEP + W    
Sbjct: 2947 TAPWIQPLKLESNSLEITVGQP-----------------IKLAFKVSGNPEPTVTWHHDD 2989

Query: 672  EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
              + PD  I V  E   +     ++I+  +    G YT+ A N  G  S     K+   E
Sbjct: 2990 RPLRPDGRIKVVKEDTTY----TMQISRSEPDDTGKYTIRAENESGHESSSTDYKLVIKE 3045

Query: 732  KEP 734
             +P
Sbjct: 3046 AKP 3048



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 1/94 (1%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            +P F+  L      +GST++ EC++ G P P + W +    I  +   +   + D    +
Sbjct: 3371 SPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGDRQILM 3430

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            +I +V P DAG +     N  G + S+  L+++A
Sbjct: 3431 II-QVRPSDAGNYRITLTNDFGVSVSSATLLIDA 3463


>UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35;
            Eutheria|Rep: Obscurin-like protein 1 precursor - Homo
            sapiens (Human)
          Length = 1401

 Score =  159 bits (385), Expect = 1e-36
 Identities = 260/1234 (21%), Positives = 475/1234 (38%), Gaps = 116/1234 (9%)

Query: 500  KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
            K +S +Q   P F+   RP     G+  + +C V G P P + W +    +  S+    +
Sbjct: 2    KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS-F 60

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTTELIVEAPLSDHGSEMTVXXXXX 618
              D     L++    P DAG + C A+NAAG A ++    ++E P SD   E+       
Sbjct: 61   PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASD--PELQPAERPL 118

Query: 619  XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG---EEIV 675
                       EG  P F   P++Q+V  G++++L CR   +PEP + W   G   +E+ 
Sbjct: 119  PSPGSG-----EG-APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVW 172

Query: 676  PDENISV--AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
               + ++      D       L+I   +    G Y   A N  G A    +L++    + 
Sbjct: 173  DSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPES 232

Query: 734  PP--------QVIEPL----KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
            PP         V+EPL    K+  V +G+       V+G P P I W    +P+  LP +
Sbjct: 233  PPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPL--LPDR 290

Query: 782  -----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836
                  D D   +  +   + KD G+Y   A NS G   ++  + V+EP      P    
Sbjct: 291  RRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP---- 346

Query: 837  NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
               Q++  +E G   L  +V  + +P+  W+R ++ + P     Q  +G    L+I  + 
Sbjct: 347  --LQDVEGREHGIAVLECKVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 403

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT- 955
            ++ D G Y C      G+    A VT+   K   +K L +  +  EG+  +L  +T    
Sbjct: 404  AD-DDGIYLC---EMRGRVRTVANVTV---KGPILKRLPRKLDVLEGENAVLLVETLEAG 456

Query: 956  VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK-- 1013
            V  +W  + +E+  +        G             D G +   + +  T+T+L VK  
Sbjct: 457  VEGRWSRDGEELPVICQS---SSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCV 513

Query: 1014 ETIPEFIRKLQDFEVKEKDVAIL---EVEINSETADVV-WERDGEIIKPKKNKYDFEKRG 1069
            +  P     L +     K+  +L     E   ET  +   ER     +     +  EK G
Sbjct: 514  KHSPPGPPILAEMFKGHKNTVLLTWKPPEPAPETPFIYRLERQEVGSEDWIQCFSIEKAG 573

Query: 1070 HIRKLYIRNTSVHDEGEYS---CILRDESCTAEVTV---VELPP--EIITRLQNQKVNKG 1121
             +    +    V  EG+Y    C +     +  V       L P   ++  L++ +V  G
Sbjct: 574  AVE---VPGDCVPSEGDYRFRICTVSGHGRSPHVVFHGSAHLVPTARLVAGLEDVQVYDG 630

Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSN----------HIQLTIDGKKQKLKIYDCDLD 1171
              A F ++L+       WF +G E++ +             ++   G + +L ++     
Sbjct: 631  EDAVFSLDLST-IIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQ 689

Query: 1172 DAGE---YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD-AYLTVEIPDETLDV 1227
            D+G    +SC     + +A LT++E  ++      +  L    ++   LT E+       
Sbjct: 690  DSGALVGFSCP--GVQDSAALTIQESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPA 747

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287
            TWYK    +E++E   +  D +K  LI+ +    D  E+ C      +     V V + P
Sbjct: 748  TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAF--FGVTVQDPP 805

Query: 1288 PKIVDYEREYRIKRG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
              IVD  RE+       S+  +L            W  + + +++        +     L
Sbjct: 806  VHIVD-PREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRL 864

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSINICW 1401
             +   + +D G ++    + C +      VTI D  S    P GK  +  +    + +  
Sbjct: 865  VLPATQPSDGGEFQCVAGDECAY----FTVTITDVSSWIVYPSGKVYVAAVRLERVVLTC 920

Query: 1402 DEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            +          + +  + +E +++   +  K  T  +  +  ++   S  +    + E+D
Sbjct: 921  ELCRPWAE---VRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEY----LCEID 973

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
               AS T    +     +I  P  E  L  +T    E + L C       P V WY+DG 
Sbjct: 974  DESASFTVTVTE--PPVRIIYPRDEVTLIAVTL---ECVVLMCELSREDAP-VRWYKDGL 1027

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
            +++ ++A    R                      D G+      V + + PV  ++ E  
Sbjct: 1028 EVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALETT 1087

Query: 1581 KQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
                 V  G+  +++  +     P V+W  NG  ++  +   +  +    V+ I+    +
Sbjct: 1088 PSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPA 1146

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            H+  YT ++    G  S+  T++V + P +   P
Sbjct: 1147 HAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAP 1180



 Score =  136 bits (329), Expect = 6e-30
 Identities = 133/533 (24%), Positives = 225/533 (42%), Gaps = 29/533 (5%)

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
            IL   K +D G   L   +  G+ + SA +T++E       P   ++    +T      +
Sbjct: 682  ILHAVKHQDSGA--LVGFSCPGVQD-SAALTIQESPVHILSPQDKVS----LTFTTSERV 734

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
             L   ++R   P+ TWY++ + +  SE +    DG    L++     + DSG+++C    
Sbjct: 735  VLTCELSRVDFPA-TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQ-DSGEFEC---R 789

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSY-ETEEGKTVILECQTSHT-VSTKWYHNKKEIS 968
            + G S+    VT+    V  V   +  +      + V+L C+        +WY + +E+ 
Sbjct: 790  TEGVSAFFG-VTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVE 848

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQD 1025
              D   +  EG             D G  +C+  D+    T T+  V   I     K+  
Sbjct: 849  ESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYV 908

Query: 1026 FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
              V+ + V +L  E+    A+V W +DGE +         +K   +R+L +    + D G
Sbjct: 909  AAVRLERV-VLTCELCRPWAEVRWTKDGEEVVESPALL-LQKEDTVRRLVLPAVQLEDSG 966

Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI--ELTKGDALVRWFKDG 1143
            EY C + DES +  VTV E P  II       +         +  EL++ DA VRW+KDG
Sbjct: 967  EYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDG 1026

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL--R 1201
             E++ S  + L  DG + +L +     +D GE+ C+ G+      +TV EP + F     
Sbjct: 1027 LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALET 1086

Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
             P  + V       L+ E+      V W      +++ E   L ++  +R L I+     
Sbjct: 1087 TPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPA 1146

Query: 1262 DQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYE-REYRIKR--GSDVTLLV 1309
                YTC    A     L   V+V E P ++V  E  + R++   G D+ L+V
Sbjct: 1147 HAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVV 1199



 Score =  118 bits (284), Expect = 2e-24
 Identities = 129/519 (24%), Positives = 212/519 (40%), Gaps = 59/519 (11%)

Query: 725  LKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPT 780
            +K  +G++  PP  +   + + V  G    L   V+G P P + W K  + + A   L  
Sbjct: 1    MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF 60

Query: 781  KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE--------- 831
             +DG  H + +L      D GVY  +A N+ G A  +A +TV EP   + E         
Sbjct: 61   PADGAEHGL-LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLP 119

Query: 832  -------PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETIT 880
                    P+F+   +   V     + L  R    P P++ W ++    +E+   S    
Sbjct: 120  SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFAL 179

Query: 881  QNF---DGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTI-----------DV 925
            Q     DG    L +  + + + DSG Y C A N+ G +  GA + +           D 
Sbjct: 180  QPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDE 239

Query: 926  EKVTFVKHLQ---KSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGR 980
                 V+ L+   K++   EGK     C          +W+   + +   D R ++   R
Sbjct: 240  APAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDR 298

Query: 981  XXXXXXXXXX--XXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDVA 1034
                          D G+  C  ++    T+    L VKE    F R LQD E +E  +A
Sbjct: 299  DGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIA 358

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            +LE ++ +      W R+ + + P + KY+  + G +R+L I      D+G Y C +R  
Sbjct: 359  VLECKVPNSRIPTAWFREDQRLLPCR-KYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGR 417

Query: 1095 SCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153
              T     V+ P  I+ RL  +  V +G  A   +E  +     RW +DG E+     I 
Sbjct: 418  VRTVANVTVKGP--ILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPV---IC 472

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             +  G    L +     +DAGE +  +GNS+ T +L V+
Sbjct: 473  QSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVK 511



 Score =  111 bits (266), Expect = 3e-22
 Identities = 139/620 (22%), Positives = 240/620 (38%), Gaps = 41/620 (6%)

Query: 729  TGEKEPPQVIEPLK--SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783
            T ++ P  ++ P    S+     E V+L+ ++     P  TW K+ + V+    L  K D
Sbjct: 709  TIQESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEESELLVVKMD 767

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843
            G  H + IL   KV+D G +  +   +EG++    V TV++P     +P   +  F    
Sbjct: 768  GRKHRL-ILPEAKVQDSGEFECR---TEGVSAFFGV-TVQDPPVHIVDPREHV--FVHAI 820

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
              E   + L   V R   P + WY++ + +  S+ +    +G +  LV+       D G+
Sbjct: 821  TSE--CVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPS-DGGE 876

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG-KTVILECQTSHT-VSTKWY 961
            ++CVA +     +    VTI       V    K Y      + V+L C+        +W 
Sbjct: 877  FQCVAGDECAYFT----VTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWT 932

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR 1021
             + +E+       + +E              D G   C + D+  S  + V E     I 
Sbjct: 933  KDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIY 992

Query: 1022 KLQDFEV--KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
               +  +     +  +L  E++ E A V W +DG  ++ +      E+ G   +L +   
Sbjct: 993  PRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVE-ESEALVLERDGPRCRLVLPAA 1051

Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEII---TRLQNQKVNKGNKATFEIELTKGDAL 1136
               D GE+ C   D+S    VTV E P + +   T      V  G       EL++  A 
Sbjct: 1052 QPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP 1111

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT----VE 1192
            V W  +G  +Q    ++L  +G ++ L I       AG Y+C+ G +     L+    V 
Sbjct: 1112 VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVA 1171

Query: 1193 EPSINFTLRLPEFILVPANT--DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            EP +           V +    D  L V +      V WYK    +    +  L     +
Sbjct: 1172 EPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGAR 1231

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRGSDVTLL 1308
            + L ++     D  EY C   DA   +++ +  VE P   K+V       +  G D T  
Sbjct: 1232 QVLRVQGARSGDAGEYLC---DAPQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFR 1288

Query: 1309 VDYQAFPQPNDEWIVNSKII 1328
             +    P  +  W+ N  ++
Sbjct: 1289 CEVSP-PDADVTWLRNGAVV 1307



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 128/619 (20%), Positives = 229/619 (36%), Gaps = 51/619 (8%)

Query: 1118 VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGE 1175
            VN+G  A F   +  K +  + W  +G  +       +  D      LK+  C   D G 
Sbjct: 257  VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 316

Query: 1176 YSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            Y C   NS    +    L V+EP + FT  L + +    +  A L  ++P+  +   W++
Sbjct: 317  YVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQD-VEGREHGIAVLECKVPNSRIPTAWFR 375

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
            +   +    K+  I +   R LII +   DD   Y C   + +   +    V    P + 
Sbjct: 376  EDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVANVTVKGPILK 432

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               R+  +  G +  LLV+          W   S+  ++      S      +L +  V 
Sbjct: 433  RLPRKLDVLEGENAVLLVE-TLEAGVEGRW---SRDGEELPVICQSSSGHMHALVLPGVT 488

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTG 1408
              DAG     L N+       + V  + K SPPG P + E+     +++ + W  PE   
Sbjct: 489  REDAGEVTFSLGNS--RTTTLLRVKCV-KHSPPGPPILAEMFKGHKNTVLLTWKPPEPAP 545

Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITK---TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             +  IY  +E QE+ + +WI   +I K    +     + +   YRFR   V     S   
Sbjct: 546  ETPFIYR-LERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGDYRFRICTV-----SGHG 599

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
             +           + +  +   L+++     ED   +     + Q   TW+ +G++LK+ 
Sbjct: 600  RSPHVVFHGSAHLVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQG--TWFLNGEELKSN 657

Query: 1526 KATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGE--------VETSCVVGIQQKPVIT 1574
            +   +                       +   D G         V+ S  + IQ+ PV  
Sbjct: 658  EPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHI 717

Query: 1575 ISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
            +S +D +       +  ++T  +  +  P   WYK+G K+E  +   +    +   + + 
Sbjct: 718  LSPQDKVSLTFTTSERVVLTCELSRVDFP-ATWYKDGQKVEESELLVVKMDGRKHRLILP 776

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVIMREISRESVTIEWKPP 1690
            E K   S ++      T G S+    + V D P     P   V +  I+ E V +  +  
Sbjct: 777  EAKVQDSGEF---ECRTEGVSAF-FGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVD 832

Query: 1691 LDDGGLELTKYAIEKHEPD 1709
             +D  +   K   E  E D
Sbjct: 833  REDAPVRWYKDGQEVEESD 851



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 5/112 (4%)

Query: 496 PVFEKPTSEEQSMAPIFVEKLR--PKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
           P    P   +++ AP+ VE L+  PK     +G   +F C V G P P+I W  +   + 
Sbjct: 229 PPESPPADPDEAPAPV-VEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLL 287

Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           P +   MY D D    L +     +D G + C A+N+AG   S  +L V+ P
Sbjct: 288 PDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 88/418 (21%), Positives = 155/418 (37%), Gaps = 34/418 (8%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C L   P  ++ W   GEE+V    + +  E  +      L +  V+    G Y +
Sbjct: 916  VVLTCELCR-PWAEVRWTKDGEEVVESPALLLQKEDTVRR----LVLPAVQLEDSGEY-L 969

Query: 711  VAVNREGEASLPIVLKIKTGEKEPP-QVIEPLK--SMIVRQGESVILSAQVVGNPRPTIT 767
              ++ E  AS  + +       EPP ++I P    ++I    E V+L  ++     P + 
Sbjct: 970  CEIDDES-ASFTVTVT------EPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAP-VR 1021

Query: 768  WCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            W K+   V+   AL  + DG    + +L   + +D G +   A       + SA  TV  
Sbjct: 1022 WYKDGLEVEESEALVLERDGPRCRL-VLPAAQPEDGGEFVCDA------GDDSAFFTVTV 1074

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
             TE   +          + V     + L   ++R   P + W  N   +   E +  + +
Sbjct: 1075 -TEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAE 1132

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV--KHLQKSYETEE 942
            G    L I        +G Y C +  + G  S    V +    V  V  +  Q    +  
Sbjct: 1133 GPRRVLCI-QAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTP 1191

Query: 943  GKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            G  + L    S      +WY + + ++     ++ Q G             D G   C  
Sbjct: 1192 GGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDA 1251

Query: 1002 KDQETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058
                   ++ V+E +  + +  L    V E D A    E++   ADV W R+G ++ P
Sbjct: 1252 PQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTP 1309



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 44/237 (18%), Positives = 87/237 (36%), Gaps = 9/237 (3%)

Query: 1461 ISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            + DA + + ++ V + E  +Q   +E     +   P E + L+C       P V W  +G
Sbjct: 1060 VCDAGDDSAFFTVTVTEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNG 1118

Query: 1520 KKLKTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            + ++  +    +    R               Y C +    G    S  V + + PV  +
Sbjct: 1119 RPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVV 1178

Query: 1576 SNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
            + E    + +   G +  +   + G P   V WYK+G +L +     +       V+R++
Sbjct: 1179 APEAAQTRVRSTPGGDLELVVHLSG-PGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQ 1237

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690
              +   + +Y  +A   +    V V   +  K      P+ + E    +   E  PP
Sbjct: 1238 GARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFRCEVSPP 1294


>UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to
            ENSANGP00000021721; n=1; Nasonia vitripennis|Rep:
            PREDICTED: similar to ENSANGP00000021721 - Nasonia
            vitripennis
          Length = 1247

 Score =  158 bits (384), Expect = 1e-36
 Identities = 136/530 (25%), Positives = 238/530 (44%), Gaps = 52/530 (9%)

Query: 539  PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
            P+  W R      P + F++ + D ++   LV + V PEDAG +TCVA+ + G  S + E
Sbjct: 666  PKFVWTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAE 725

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            L V+  ++                      + E   P    + +   V  G   +L+ ++
Sbjct: 726  LTVQGTVNQL--------------------LKEPAKPALQSESRTSEVSAGGSAMLDLQV 765

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
               P+P+I W   G+EIV    I    E +  +    L I +V     G Y + A N  G
Sbjct: 766  KGFPKPNITWTKDGKEIVAGGRIKYLWEDEESLS---LVIKSVTAADAGVYKIRARNELG 822

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775
            E +  I L +K+     P++ + ++S  V+  E++ +S Q+ G+P P ++W K+NK +  
Sbjct: 823  EDNTQIELIVKSA----PKITKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILE 878

Query: 776  --KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV--ITVEEPTEENAE 831
              +   +K   DT+++TI K   ++D G Y++ A+N   I ETS     TV+ P      
Sbjct: 879  SDRTRISKEADDTYTLTI-KSACLEDSGSYSIIAKNE--INETSQFWDCTVKYP------ 929

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
            P +     +   ++E  ++ L   V  +  PS+TW ++ E+I  S+ IT + +G    L 
Sbjct: 930  PKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWIKDEEVIKISDRITISDEGNRHSLQ 989

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILE 949
            I  +  + D+  YK   +N  G  S    + +    + F K LQ    TE    V  + +
Sbjct: 990  IDKL-LDTDTATYKVQVANKDGARSEQTAIQVRSAPL-FKKKLQDKTATENEANVELLAQ 1047

Query: 950  CQTSHTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QE 1005
             ++       WY   K+IS       + +EG               G   C  K+   + 
Sbjct: 1048 VESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGES 1107

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGE 1054
            +S+  +     P+ I+KL D +VKE +   L V++++  A +V W +DG+
Sbjct: 1108 SSSASLTVNFRPKLIKKLADQKVKEGETLKLTVQVSAVPAPEVQWFKDGQ 1157



 Score =  157 bits (382), Expect = 2e-36
 Identities = 186/797 (23%), Positives = 337/797 (42%), Gaps = 75/797 (9%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPD-IAWLFKGEEIVPDENISVAIESDMHMYC 692
            P F    +   V+ G     EC L +      + WL   + +  D+ ++  + S +    
Sbjct: 443  PQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPM--DDKLADRVRSSVEGST 500

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGE 750
              L+I NV +   G Y   A N EG A+    L ++  T E++  +        +VR  +
Sbjct: 501  YKLQIENVLESDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANSPIFLVRLKD 560

Query: 751  SVILS-------AQVVGNPRPTITWCKNNKP-------VKALPTKSDGDTHSITILKPKK 796
            + +L         ++ G+P P + + K+  P       V+ +  K+D   + I I   +K
Sbjct: 561  TELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFYEIVIPDVQK 620

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             +D G Y+  A+N  G A   A ++V +     A  P             +G ++  A  
Sbjct: 621  -QDAGKYSCTAQNRFGEASCEASVSVTDEKLMFAGLP-------------EGLLEPGAE- 665

Query: 857  TRNPVPSITWYRNNEIISPSETITQNF-DGEN-IELVITNVDSEIDSGDYKCVASNSAGK 914
                 P   W R+     P E     F D E+ + LV  +V  E D+G Y CVA  S G 
Sbjct: 666  -----PKFVWTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPE-DAGLYTCVAQTSTGN 719

Query: 915  SSHGARVTIDVEKVTFVKH-----LQKSYETEE---GKTVILECQTSH--TVSTKWYHNK 964
             S  A +T+       +K      LQ    T E   G + +L+ Q       +  W  + 
Sbjct: 720  ISCSAELTVQGTVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDG 779

Query: 965  KEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTML-VVKETIPEFI 1020
            KEI +G   + + ++              D GV K   +++  E +T + ++ ++ P+  
Sbjct: 780  KEIVAGGRIKYLWEDEESLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKIT 839

Query: 1021 RKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
            ++++ F V+ ++   + V+I  S   +V W +D + I         ++      L I++ 
Sbjct: 840  KRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSA 899

Query: 1080 SVHDEGEYSCILRDE-SCTAEV--TVVELPPEIITRLQNQK-VNKGNKATFEIELTKG-D 1134
             + D G YS I ++E + T++     V+ PP+I   L   + + +G+  T  +E+     
Sbjct: 900  CLEDSGSYSIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYP 959

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGN-----SKCTAI 1188
              V W KD   I+ S+ I ++ +G +  L+I D  LD D   Y  +V N     S+ TAI
Sbjct: 960  PSVTWIKDEEVIKISDRITISDEGNRHSLQI-DKLLDTDTATYKVQVANKDGARSEQTAI 1018

Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISD 1247
                 P     L+        AN +    VE   +  +V+WY   K + E+ +++++  +
Sbjct: 1019 QVRSAPLFKKKLQDKTATENEANVELLAQVESFSKP-EVSWYFAGKKISEEKKEYSMSEE 1077

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVT 1306
                 L I+    +   +YTC   +    +     + V F PK++    + ++K G  + 
Sbjct: 1078 GNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIKKLADQKVKEGETLK 1137

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS---KSASLTIKKVENTDAGIYKLRLE 1363
            L V   A P P  +W  + + +      K S DS   ++  LT+  ++ TD G+Y++R +
Sbjct: 1138 LTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKGTDGGVYEVRAK 1197

Query: 1364 NNCGHADVEMNVTILDK 1380
            N+ G    +  V +L K
Sbjct: 1198 NDLGFVSSKSKVIVLTK 1214



 Score =  143 bits (347), Expect = 4e-32
 Identities = 151/693 (21%), Positives = 291/693 (41%), Gaps = 42/693 (6%)

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT-ITWCKNNKPVK-----AL 778
            L + T +   PQ   P++   V  GE       +  +   + + W K+NKP+       +
Sbjct: 433  LALSTNDAGRPQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPMDDKLADRV 492

Query: 779  PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE------NAEP 832
             +  +G T+ + I    +  D G+Y   A N EG A  +A + V+E T E      +A  
Sbjct: 493  RSSVEGSTYKLQIENVLE-SDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANS 551

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS----ETITQNFDGENI 888
            P+F+ R ++  + E   ++ + ++  +P P + ++++   I       + + +  D    
Sbjct: 552  PIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFY 611

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET-EEGKTVI 947
            E+VI +V  + D+G Y C A N  G++S  A V++  EK+ F    +   E   E K V 
Sbjct: 612  EIVIPDVQKQ-DAGKYSCTAQNRFGEASCEASVSVTDEKLMFAGLPEGLLEPGAEPKFVW 670

Query: 948  LECQTSHTVSTKW---YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
                       ++   + + ++   +  + +  E              ++      +  Q
Sbjct: 671  TRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNIS-CSAELTVQ 729

Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNK 1062
             T   L+ +   P    + +  EV     A+L++++      ++ W +DG EI+   + K
Sbjct: 730  GTVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIK 789

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVN 1119
            Y +E    +  L I++ +  D G Y    R+   E  T    +V+  P+I  R+++  V 
Sbjct: 790  YLWEDEESL-SLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKITKRMESFSVQ 848

Query: 1120 KGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG-KKQKLKIYDCDLDDAGEY 1176
                    +++ +G  +  V W+KD   I  S+  +++ +      L I    L+D+G Y
Sbjct: 849  SEETINMSVQI-QGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSACLEDSGSY 907

Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            S     E+  +      TV+  P I   L  P  I    +   Y+ VE  D    VTW K
Sbjct: 908  SIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIEEGDSLTLYVEVE-SDYPPSVTWIK 966

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPK 1289
             + VI+ +++ T+  +  + +L I K  + D   Y   +   D   + +  ++V   P  
Sbjct: 967  DEEVIKISDRITISDEGNRHSLQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSAPLF 1026

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIK 1348
                + +   +  ++V LL   ++F +P   W     KI ++ K    S +     LTIK
Sbjct: 1027 KKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIK 1086

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              +   AG Y  + +N  G +    ++T+  +P
Sbjct: 1087 SAKTECAGKYTCKAKNEVGESSSSASLTVNFRP 1119



 Score =  127 bits (306), Expect = 4e-27
 Identities = 158/692 (22%), Positives = 273/692 (39%), Gaps = 57/692 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETAD-VVWERDGEIIKPK-KNKYDFEKRGHIRK 1073
            P+F   ++  +V+  + A  E  + +SE+A  +VW +D + +  K  ++      G   K
Sbjct: 443  PQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPMDDKLADRVRSSVEGSTYK 502

Query: 1074 LYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPE------------IITRLQNQK 1117
            L I N    D G Y     +     +CTA++ V E   E             + RL++ +
Sbjct: 503  LQIENVLESDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANSPIFLVRLKDTE 562

Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQK----LKIYDCDLD 1171
            + +     F I++ KGD    +++FKDG  I   N     +  K  K    + I D    
Sbjct: 563  LLENTYLRFMIKI-KGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFYEIVIPDVQKQ 621

Query: 1172 DAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-----PD 1222
            DAG+YSC      G + C A ++V +  + F   LPE +L P     ++         P+
Sbjct: 622  DAGKYSCTAQNRFGEASCEASVSVTDEKLMFA-GLPEGLLEPGAEPKFVWTRDGVPFDPE 680

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            E   V +   +  +    +     D    T + +  T +  C  +  L    +  +L  E
Sbjct: 681  ERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNISC--SAELTVQGTVNQLLKE 738

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSK 1341
              +  P +    R   +  G    L +  + FP+PN  W  + K I      K    D +
Sbjct: 739  PAK--PALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIKYLWEDEE 796

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            S SL IK V   DAG+YK+R  N  G  + ++ + +   P    +     + S       
Sbjct: 797  SLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKITKRMESFSVQSEETINMS 856

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460
             + + +    + +Y    + +++      K    T T +I++     S  +   A NE++
Sbjct: 857  VQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSACLEDSGSYSIIAKNEIN 916

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
                 ET++++     T    P + K L +    E  + + L         P VTW +D 
Sbjct: 917  -----ETSQFWDC---TVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWIKDE 968

Query: 1520 KKLKTA-KATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            + +K + + T     NR               YK    N  G       + ++  P+   
Sbjct: 969  EVIKISDRITISDEGNRHSLQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSAPLFKK 1028

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKE 1634
              +D        +  L+ A +E    PEV WY  G K+ E  KEY+++ +     + IK 
Sbjct: 1029 KLQDKTATENEANVELL-AQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIKS 1087

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             K   + KYT +A N  G SS   +L V  +P
Sbjct: 1088 AKTECAGKYTCKAKNEVGESSSSASLTVNFRP 1119



 Score =  117 bits (282), Expect = 3e-24
 Identities = 156/717 (21%), Positives = 280/717 (39%), Gaps = 77/717 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+ +L+D E+ E       ++I  + A D+ + +DG  I  K  +    +    +  Y
Sbjct: 552  PIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFY 611

Query: 1076 ---IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
               I +    D G+YSC  ++     SC A V+V +    +   L    +  G +  F  
Sbjct: 612  EIVIPDVQKQDAGKYSCTAQNRFGEASCEASVSVTD-EKLMFAGLPEGLLEPGAEPKFV- 669

Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL--DDAGEYSC----EVGN 1182
                      W +DG         ++     +  L +    +  +DAG Y+C      GN
Sbjct: 670  ----------WTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGN 719

Query: 1183 SKCTAILTVEEPSINFTLRLP---------EFILVPANTDAYLTVEIPD-ETLDVTWYKK 1232
              C+A LTV+  ++N  L+ P             V A   A L +++      ++TW K 
Sbjct: 720  ISCSAELTVQG-TVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKD 778

Query: 1233 -KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKI 1290
             K ++       L  D +  +L+I+  T  D   Y     +       ++E +V+  PKI
Sbjct: 779  GKEIVAGGRIKYLWEDEESLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKI 838

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKK 1349
                  + ++    + + V  Q  P P   W  ++K I +   T+ S ++    +LTIK 
Sbjct: 839  TKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKS 898

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPEN 1406
                D+G Y +  +N         + T+   P      G+P ++E               
Sbjct: 899  ACLEDSGSYSIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIE--------------- 943

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD--A 1464
             G+S  +Y  VE     +  WI  + + K    I      + +  +   + + D +    
Sbjct: 944  EGDSLTLYVEVESDYPPSVTWIKDEEVIKISDRITISDEGNRHSLQIDKLLDTDTATYKV 1003

Query: 1465 SETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNE-DIELTCIFGGVPQPKVTWYRDGK 1520
                +     ++T IQ   +P  +K L++ T   NE ++EL        +P+V+WY  GK
Sbjct: 1004 QVANKDGARSEQTAIQVRSAPLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGK 1063

Query: 1521 KLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            K+   K  Y      N                Y C A N+ GE  +S  + +  +P +  
Sbjct: 1064 KISEEKKEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIK 1123

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKTSVIRI 1632
               D  QK K G+   +T  +  +P PEV W+K+G ++  D    I   + + +   + +
Sbjct: 1124 KLAD--QKVKEGETLKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTV 1181

Query: 1633 KELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
              LK +    Y + A N  G   + S  + L   ++ S+    V   ++S +  T E
Sbjct: 1182 TLLKGTDGGVYEVRAKNDLGFVSSKSKVIVLTKSEEQSEEATKVAEEDVSAQKQTAE 1238



 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 98/425 (23%), Positives = 180/425 (42%), Gaps = 58/425 (13%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP   +++         T+    Q++G P P+++W++    I  S   ++  + D+    
Sbjct: 835  APKITKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADD---- 890

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
                       T+T   K+A               L D GS  ++             D 
Sbjct: 891  -----------TYTLTIKSAC--------------LEDSGS-YSIIAKNEINETSQFWDC 924

Query: 629  LEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIES 686
                PP  +K   + + ++EG  + L   + +   P + W+ K EE++   + I+++ E 
Sbjct: 925  TVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWI-KDEEVIKISDRITISDEG 983

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            + H     L+I  +      TY V   N++G  S    +++++     P   + L+    
Sbjct: 984  NRHS----LQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSA----PLFKKKLQDKTA 1035

Query: 747  RQGES-VILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEG 801
             + E+ V L AQV    +P ++W    K +    K      +G+ + +TI K  K +  G
Sbjct: 1036 TENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTI-KSAKTECAG 1094

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             YT KA+N  G + +SA +TV      N  P L I +  +  VKE  T+KL  +V+  P 
Sbjct: 1095 KYTCKAKNEVGESSSSASLTV------NFRPKL-IKKLADQKVKEGETLKLTVQVSAVPA 1147

Query: 862  PSITWYRNNEIISPSETITQNFDG---ENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            P + W+++ + ++    I  + D    EN +L +T +    D G Y+  A N  G  S  
Sbjct: 1148 PEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKG-TDGGVYEVRAKNDLGFVSSK 1206

Query: 919  ARVTI 923
            ++V +
Sbjct: 1207 SKVIV 1211



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 55/206 (26%), Positives = 101/206 (49%), Gaps = 17/206 (8%)

Query: 634  PTFSKKPKAQYVDEG-SDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDMHMY 691
            P F KK + +   E  +++ L  ++ +  +P+++W F G++I  ++   S++ E +    
Sbjct: 1024 PLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGN---- 1079

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            C  L I + K    G YT  A N  GE+S    L +       P++I+ L    V++GE+
Sbjct: 1080 CYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFR----PKLIKKLADQKVKEGET 1135

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG---DTHSITILKPKKVKDEGVYTL 805
            + L+ QV   P P + W K+ + V A   +    D    + + +T+   K   D GVY +
Sbjct: 1136 LKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKGT-DGGVYEV 1194

Query: 806  KAENSEGIAETSAVITVEEPTEENAE 831
            +A+N  G   + + + V   +EE +E
Sbjct: 1195 RAKNDLGFVSSKSKVIVLTKSEEQSE 1220



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 3/101 (2%)

Query: 502  TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMY 559
            T+ +   AP+F +KL+ K  T + + V+   QVE + +P+++W F    I +  +++ M 
Sbjct: 1016 TAIQVRSAPLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMS 1075

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             ++ N   L I+    E AG +TC AKN  G +SS+  L V
Sbjct: 1076 -EEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTV 1115



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 27/93 (29%), Positives = 46/93 (49%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P    + R      G +   + QV+G+P+P ITW +    I      +  ++D+   +LV
Sbjct: 742 PALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIKYLWEDEESLSLV 801

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
           I+ V   DAG +   A+N  G  ++  ELIV++
Sbjct: 802 IKSVTAADAGVYKIRARNELGEDNTQIELIVKS 834



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 48/174 (27%), Positives = 73/174 (41%), Gaps = 24/174 (13%)

Query: 455  WWYVQKHLTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMA--- 509
            W++  K ++EEK     +Y M E  N Y   ++    E   K     K    E S +   
Sbjct: 1058 WYFAGKKISEEK----KEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASL 1113

Query: 510  -----PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ------TAIIKPSQDFQM 558
                 P  ++KL  +   +G T++   QV   P P++ WF+        A IK S+D Q 
Sbjct: 1114 TVNFRPKLIKKLADQKVKEGETLKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQR 1173

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
              + D   TL    +   D G +   AKN  GF SS +++IV     +   E T
Sbjct: 1174 LENYDLTVTL----LKGTDGGVYEVRAKNDLGFVSSKSKVIVLTKSEEQSEEAT 1223



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 1/137 (0%)

Query: 597  ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
            +L +++  ++   + T             A +     P   KK   Q V EG  + L  +
Sbjct: 1082 KLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIKKLADQKVKEGETLKLTVQ 1141

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
            + A+P P++ W   G+E+  D  I ++ +S   +    L +T +K    G Y V A N  
Sbjct: 1142 VSAVPAPEVQWFKDGQEVNADARIKISRDS-QRLENYDLTVTLLKGTDGGVYEVRAKNDL 1200

Query: 717  GEASLPIVLKIKTGEKE 733
            G  S    + + T  +E
Sbjct: 1201 GFVSSKSKVIVLTKSEE 1217



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 3/105 (2%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQ 557
           E+  +   + +PIF+ +L+     + + ++F  +++G P P + +F+    I   ++  Q
Sbjct: 541 EEKKARADANSPIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQ 600

Query: 558 MYYD--DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           +  +  D     +VI +V  +DAG ++C A+N  G AS    + V
Sbjct: 601 IVREKADKGFYEIVIPDVQKQDAGKYSCTAQNRFGEASCEASVSV 645


>UniRef50_Q86VF2 Cluster: EEF1A2 binding protein; n=9;
            Euteleostomi|Rep: EEF1A2 binding protein - Homo sapiens
            (Human)
          Length = 868

 Score =  157 bits (382), Expect = 2e-36
 Identities = 106/473 (22%), Positives = 196/473 (41%), Gaps = 11/473 (2%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547
            L ++  +P E   L+C       P  TW++DG KL T       +               
Sbjct: 79   LADMEVQPGEAATLSCTLTSDLGPG-TWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGT 137

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITIS-NEDIKQKH--KVGDEWLVTAVIEGIPPPEV 1604
                     G+ ++   + +Q  P I     E +++    K G   +V    +   P + 
Sbjct: 138  QAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQA 197

Query: 1605 IWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             W K+G ++   +D+E  +   +  + + +    R    +Y++   +  G+   E+TL+V
Sbjct: 198  AWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQV 257

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             DKP  P+GP+ +++  R  V + W+PP D+GG  +  Y +E+ +   + W+KV +   D
Sbjct: 258  IDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPAD 317

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
              T+    +    +Y FRV A    G  EALESE I++  A +               ++
Sbjct: 318  STTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILV--APEALPKAPSAPAILSASSQ 375

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRI 1839
             + +TW      G + I+ Y +E +++G   W           R  +  +     Y+FR+
Sbjct: 376  GITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRV 435

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             A    G   P    D +     + PP   RN  V++ ++ S+TL W  P++  G     
Sbjct: 436  TAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQG 495

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
            Y++E  +     W         V  +  + ++  +    R++A N  G S P+
Sbjct: 496  YVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPS 548



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 150/686 (21%), Positives = 264/686 (38%), Gaps = 41/686 (5%)

Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172
            L + +V  G  AT    LT       WFKDG ++   + +    DG    L I       
Sbjct: 79   LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQ 138

Query: 1173 AGEYSCEVGNSKCTAILTVEE-PSI--NFTLRLPEFILVPANTDAYLTVEIPDET-LDVT 1228
            AG Y+   G+ +  A LTV++ P+I  + T +L E ++V A     + +       +   
Sbjct: 139  AGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAA 198

Query: 1229 WYKKKSVI---EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283
            W K  + +    D E    + D   R L +      D  +Y+  L     + +  L ++V
Sbjct: 199  WRKDGAEVVGSSDREAQVDLGDGYTR-LCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQV 257

Query: 1284 VEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS-IDSK 1341
            ++ P P     E +   + G  +          +  + ++V  +   +    K     + 
Sbjct: 258  IDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPAD 317

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP----PGKPNILEIDSSSI 1397
            S + T   VE      +++R   + G  +   +  IL  P      P  P IL   S  I
Sbjct: 318  STTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGI 377

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
             + W  P   G++ I+ Y++E ++  +  W +V +  + + + ++ +++    Y FR  A
Sbjct: 378  TLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTA 437

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF-----GGVPQ 1510
            V      +    ++   V     ++ P + + L+ +T   N  I L+        G   Q
Sbjct: 438  VAPSGPGEPGPPSD--AVFARDPMRPPGLVRNLQ-VTDRSNTSITLSWAGPDTQEGDEAQ 494

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQ 1568
              V        L+                        Y  +  A N+ G+ + S +  + 
Sbjct: 495  GYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLV 554

Query: 1569 QKPVITISNE---DIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            Q   +T+  +   D   K     KVGD   V    E +P PEV W K+G  L   K    
Sbjct: 555  QAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDG--LPLPKRSVT 612

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISR 1680
             TK+  + + I     S S  YT+      G   +    ++V   P  P GP+ ++E   
Sbjct: 613  VTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQAP-GPIHLQENVP 671

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
             +VT EW+P  D+       YA+      +  W + AD       + +  +    EY FR
Sbjct: 672  GTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAAD-RIYTNRFTLLGILPGHEYHFR 730

Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALD 1765
            V+A+N +G S+  + S+P  I    D
Sbjct: 731  VVAKNELGASKPSDTSQPWCIPRQRD 756



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 101/474 (21%), Positives = 169/474 (35%), Gaps = 36/474 (7%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W+K+G KL                + I  ++ + + +YT      AG    E TL V D 
Sbjct: 105  WFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTF----VAGDQQSEATLTVQDS 160

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK-----VADVD 1720
            P+    P +  ++ RE + ++   P+      + K   + H P    W K     V   D
Sbjct: 161  PTI--APDVTEKL-REPLVVKAGKPV------IVKIPFQSHLPIQAAWRKDGAEVVGSSD 211

Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTAL-----DVPSXXXXXX 1774
            R+ +          C        +   G +S  L SE   ++  L     D P       
Sbjct: 212  REAQVDLGDGYTRLC---LPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPM 268

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT 1833
                     V + W P   NGG  +  Y VE +Q G+  W                 +  
Sbjct: 269  EVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEP 328

Query: 1834 --TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
               Y FR+ A    G      S++ +   + L  P  P    +  ++S+ +TL WT P  
Sbjct: 329  GRKYTFRVRAVTSEGAGEALESEEILVAPEAL--PKAPSAPAILSASSQGITLTWTAPRG 386

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
             G + I  Y+IE +     +WT +           + ++++  +  FR++A    G   P
Sbjct: 387  PGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEP 446

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
                     +    P      L++    +  +  SW  P+   G    GY + +      
Sbjct: 447  GPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSL 506

Query: 2012 MWM--EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             W+   VG V V T  +  + L     Y +R+ A NE G S+P   D   + +P
Sbjct: 507  QWLPCHVGTVPVTT--YTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMP 558



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 97/435 (22%), Positives = 166/435 (38%), Gaps = 27/435 (6%)

Query: 1637 RSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
            R ++ +     S  AG +  S E+ +     P  P  P I+   S + +T+ W  P   G
Sbjct: 330  RKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAIL-SASSQGITLTWTAPRGPG 388

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
               +  Y IE+ +  +N W  V D       + +  + + C+Y FRV A  P G  E   
Sbjct: 389  SAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGP 448

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813
                V       P             N S+ ++W   +   G     Y VE+   +  +W
Sbjct: 449  PSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQW 508

Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
                           + L     Y  R+ A NE G S P   D   T+ + +     P+ 
Sbjct: 509  LPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALD---TLVQAMPVTVCPK- 564

Query: 1872 FVVSESTSRSVTLKWTE----PESNGGSPI--TNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            F+V  ST   +T+K  +    P S    P+    ++ +   +  +S T  VT  G + + 
Sbjct: 565  FLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVT--VTKDG-LTQL 621

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
             I      D  ++ +      G  +   + S R+ + A  P  P  P+ ++      V  
Sbjct: 622  LIPVAGLSDSGLYTVVLRTLQGKEV---AHSFRI-RVAACPQAP-GPIHLQENVPGTVTA 676

Query: 1986 SWG-TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
             W  +P+     PL  Y +  R      W E     + T +F +  +   H Y  R+ A+
Sbjct: 677  EWEPSPDEAQDVPL-HYAVFTRSSAHGPWHEAAD-RIYTNRFTLLGILPGHEYHFRVVAK 734

Query: 2045 NEIGLSEPLESDEPF 2059
            NE+G S+P ++ +P+
Sbjct: 735  NELGASKPSDTSQPW 749



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 67/326 (20%), Positives = 120/326 (36%), Gaps = 8/326 (2%)

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
            H+     GK  +L IY    D     +        +     + P  +F+  L +  + P 
Sbjct: 28   HLGSRRSGKDGRLDIYGERRDATRSSTSRYKPGTGSFSKDAQGPMGHFSQGLADMEVQPG 87

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
               A L+  +  +    TW+K    +   +      D    +L I          YT V 
Sbjct: 88   EA-ATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVA 146

Query: 1271 LDAKSTTKLKVE-VVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
             D +S   L V+      P + +  RE   +K G  V + + +Q+       W  +   +
Sbjct: 147  GDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEV 206

Query: 1329 KKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-G 1385
                  +  +D       L +      D G Y + L +  G    E+ + ++DKP PP G
Sbjct: 207  VGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQG 266

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNL 1443
               + +   + + + W  P + G  T+  YVVE ++   + W+ V       T+    ++
Sbjct: 267  PMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHV 326

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTE 1469
            +    Y FR  AV      +A E+ E
Sbjct: 327  EPGRKYTFRVRAVTSEGAGEALESEE 352



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 39/111 (35%), Positives = 55/111 (49%), Gaps = 6/111 (5%)

Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
           K P + +P   + S  P F+  LR    P G      C V+G PRP +TWF+    ++ +
Sbjct: 761 KAPCYREP---DLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGN 817

Query: 554 QDFQMYYDD-DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
               +Y  D   V +L I  V P+D+G +  VA+N  G A ST  LIV  P
Sbjct: 818 P--AVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEP 866



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 2/96 (2%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
           + P+ +  L+S ++ QG    +S  V G+PRP +TW KN++ ++  P     D   +  L
Sbjct: 772 QKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSL 831

Query: 793 KPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPT 826
               V  KD G Y   AEN+ G A ++A + V EP+
Sbjct: 832 TIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEPS 867



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 48/247 (19%), Positives = 98/247 (39%), Gaps = 18/247 (7%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +K G  V + V ++A P P   W+ +   + K   T          L I     +D+G+Y
Sbjct: 577  VKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVTVTK--DGLTQLLIPVAGLSDSGLY 634

Query: 1359 KLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             + L    G        + +   P  PG  ++ E    ++   W+   +      ++Y V
Sbjct: 635  TVVLRTLQGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAV 694

Query: 1418 EYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
              +      W  +   I   + ++  +     Y FR  A NE+  S  S+T++ + + ++
Sbjct: 695  FTRSSAHGPWHEAADRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQ 754

Query: 1477 T---KIQSPTVEKP-----------LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                 +++P   +P           L++       +  ++C   G P+P VTW+++ + L
Sbjct: 755  RDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSL 814

Query: 1523 KTAKATY 1529
            +   A Y
Sbjct: 815  EGNPAVY 821



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 10/167 (5%)

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
            F + L D EV+  + A L   + S+     W +DG  +  +     F++ G +  L+I +
Sbjct: 75   FSQGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVI-FKQDGLVHSLFITH 133

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIELTKGDA 1135
                  G Y+ +  D+   A +TV + P   P++  +L+   V K  K    +++     
Sbjct: 134  VQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVI-VKIPFQSH 192

Query: 1136 L---VRWFKDGSEIQFSN--HIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
            L     W KDG+E+  S+    Q+ +     +L +      D G+YS
Sbjct: 193  LPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYS 239



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 22/78 (28%), Positives = 33/78 (42%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E  ++  ++G P P V W+KN   LE +     T       + I  +    S +Y   
Sbjct: 788  GCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAV 847

Query: 1647 ASNTAGTSSVEVTLKVYD 1664
            A NT G +    TL V +
Sbjct: 848  AENTLGQAVSTATLIVIE 865



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 7/128 (5%)

Query: 800 EGVYT-LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARV 856
           EG +  + A N  G ++ SA+ T+ +       P   ++   +  +TVK   T+++    
Sbjct: 530 EGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSF 589

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS- 915
              P+P +TW ++  +  P  ++T   DG  +  ++  V    DSG Y  V     GK  
Sbjct: 590 EAMPMPEVTWLKDG-LPLPKRSVTVTKDG--LTQLLIPVAGLSDSGLYTVVLRTLQGKEV 646

Query: 916 SHGARVTI 923
           +H  R+ +
Sbjct: 647 AHSFRIRV 654


>UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gambiae
            str. PEST|Rep: ENSANGP00000024414 - Anopheles gambiae
            str. PEST
          Length = 2305

 Score =  157 bits (381), Expect = 3e-36
 Identities = 145/602 (24%), Positives = 257/602 (42%), Gaps = 57/602 (9%)

Query: 459  QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLR 517
            QK + E    +  + + ++    +  Q++++E KI +  V     S+ +   P  VEKL+
Sbjct: 1572 QKRVQEVTDKIAEESVREDRQLIETTQQQISETKIQEQTV---KISKPKVQPPNIVEKLQ 1628

Query: 518  PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
            P+       V   C++EG P P + W+    ++  S ++ M   +D VATL I  V P  
Sbjct: 1629 PQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVED-VATLEIATVQPYH 1687

Query: 578  AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
             G +TC AKN AG A S   ++V+    +HG                         P F 
Sbjct: 1688 VGIYTCEAKNVAGVAISKANIVVQEK-PEHGEA-----------------------PRFV 1723

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
               K +  ++ +   + C++  IP P + WL    EI+ +E   +    +       L +
Sbjct: 1724 VPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTV 1783

Query: 698  TNVKKFQEGTYTVVAVNREGEAS-------LPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
             + K+     +TVVA N+ G+A          +V++        PQ+++PL++ +VR G 
Sbjct: 1784 KHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGS 1843

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS-ITILKPKKVKDE--GVYTLKA 807
            +++   +  G P+PT+ W +N+K +     +    T    + L+ ++V  +  G Y +  
Sbjct: 1844 TLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITV 1903

Query: 808  ENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
             N  G A++SA + + + T+ + A+ P FI       + E     L A V   P  +  W
Sbjct: 1904 TNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQW 1963

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV----T 922
            ++    I  S    +    EN  ++I    +  D+G Y C A N AG  +  A V    T
Sbjct: 1964 FKEGAAIK-STNEQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDT 2022

Query: 923  IDVEKVT------FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHRE 974
            I+ E+VT      F++ + K     +G+ + LECQ       K  WYHN + I     ++
Sbjct: 2023 IETEEVTEYISPRFLETI-KPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQ 2081

Query: 975  IIQEGRXX-XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEK 1031
            + Q+               D G   C+  ++  E      V     E++   + F   E+
Sbjct: 2082 VQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEE 2141

Query: 1032 DV 1033
            D+
Sbjct: 2142 DL 2143



 Score =  118 bits (284), Expect = 2e-24
 Identities = 121/510 (23%), Positives = 205/510 (40%), Gaps = 45/510 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP   +K + Q  +    +LL CR+  +P P + W F    +       + +  D+    
Sbjct: 1620 PPNIVEKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDV---- 1675

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            + L+I  V+ +  G YT  A N  G A     IV++ K    E P+ + PLK  +  Q  
Sbjct: 1676 ATLEIATVQPYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLKIELNEQKT 1735

Query: 751  SVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDT-HSITILKPKKVKDEGVYT 804
               ++ QV G P P + W ++   +     + + T  +  T H    +K  K     V+T
Sbjct: 1736 IATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFT 1795

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTRNP 860
            + AEN  G A   A + ++    E A+P    P  +   +   V+   T+    R T  P
Sbjct: 1796 VVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQP 1855

Query: 861  VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             P++ W+RN+ EI+   E +    +     L I  V  +   G Y+   +N AG++   A
Sbjct: 1856 KPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQ-RGGKYEITVTNEAGQAKSSA 1914

Query: 920  RVTI----DVEKVTFVKHLQKSYE--TEEGKTVILECQT-SHTVST-KWYHNKKEISGMD 971
             V I    D ++    + ++        E +  ILE    S+  ST +W+     I   +
Sbjct: 1915 SVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTN 1974

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKC---IVKDQETSTMLV----------VKETI-P 1017
             + I+ +              D G   C    V    TST  V          V E I P
Sbjct: 1975 EQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISP 2034

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             F+  ++   V + +   LE ++ +     V W  + ++I+  K+K   +       L I
Sbjct: 2035 RFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSI 2094

Query: 1077 RNTSVHDEGEYSCI----LRDESCTAEVTV 1102
                  D+GEY+C+    + +  C A V V
Sbjct: 2095 SEVFPEDKGEYTCVATNKIGEAICRATVNV 2124



 Score =  106 bits (255), Expect = 6e-21
 Identities = 131/561 (23%), Positives = 226/561 (40%), Gaps = 90/561 (16%)

Query: 350  DIVESKKDENEIIQEKQT-----LEELPKEDVPEQYTITPRKSSAQKIDE--IVDEVTIK 402
            +I+E +++E E   E++T       + PK++VP  +T+       + + +  +  +  + 
Sbjct: 1759 EIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVM 1818

Query: 403  KRLNPFEI---FYTPVE---VRCGDTVFAVYSYVAETDEAIN-------LVEGERLYILD 449
            +R  P  +      P+E   VR G T+     +  +    +        +VE E   I+ 
Sbjct: 1819 ERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIIT 1878

Query: 450  TSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMA 509
            T         + +T ++G    +Y +   N     Q K +  +         T  +++ A
Sbjct: 1879 TEEYYSRLEIRRVTRQRG---GKYEITVTNEAG--QAKSSASV----AISDATDTDEAKA 1929

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+E L PK   +      E  VE YP     WF++ A IK + + Q     +N + L+
Sbjct: 1930 PRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNE-QRIVTKENRSILI 1988

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I      D G +TC A+N AG  +ST  +                            ++ 
Sbjct: 1989 IESFTRRDTGAYTCRAENVAGSVTSTATV-------------------QTLDTIETEEVT 2029

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E I P F +  K   V +G  + LEC++VA+P P + W    + I   E     ++ D  
Sbjct: 2030 EYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLI--QETKDKQVQQDST 2087

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--------------- 734
              C VL I+ V    +G YT VA N+ GEA     + ++  E  P               
Sbjct: 2088 GRC-VLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEEDLLTD 2146

Query: 735  ------PQVIEPLK--SMIVRQGESVI---------LSAQVVGNPRPTITWCKNNK---P 774
                   +  EP++    IV+Q  ++I         L  +V+ +P+P I W K  +   P
Sbjct: 2147 KSISTLEEYAEPIEYAPQIVKQLPTIIHSQERELTKLEVKVLAHPKPQIRWLKAGEEIIP 2206

Query: 775  VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA-EPP 833
                  ++  D  SI I+      D G  T +A N+ G+A T+  + VEE     A   P
Sbjct: 2207 SDEFQIENFDDGTSILIINDIYPDDSGEITFEAHNALGVAMTTTELVVEEIVGTKAYRKP 2266

Query: 834  LFINRFQEI--TVKEKGTIKL 852
             ++   +E+   ++E  T +L
Sbjct: 2267 EWVQHMEELKEALQESSTEEL 2287



 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 136/561 (24%), Positives = 218/561 (38%), Gaps = 75/561 (13%)

Query: 435  EAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDK 494
            + I ++E E   I     +   +V+  +   K  VP  + +   N       K N  I  
Sbjct: 1756 DEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQS 1815

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            + V E+  ++  ++AP  V+ L  +    GST+ FEC+  G P+P + WFR +  I   +
Sbjct: 1816 V-VMER--AKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEE 1872

Query: 555  DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
            +  +   ++  + L IR V  +  G +     N AG A S+  + +    SD        
Sbjct: 1873 EEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSASVAI----SD-------- 1920

Query: 615  XXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
                        D  E   P F +    + + E    +LE  + + P     W  +G  I
Sbjct: 1921 ----------ATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAI 1970

Query: 675  VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKE 733
                   +  + +     S+L I +  +   G YT  A N  G   S   V  + T E E
Sbjct: 1971 KSTNEQRIVTKENR----SILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETE 2026

Query: 734  ------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDT 786
                   P+ +E +K   V  GE + L  QVV  P P + W  N + ++    K    D+
Sbjct: 2027 EVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDS 2086

Query: 787  HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE--------------------- 823
                +L   +V  +D+G YT  A N  G A   A + VE                     
Sbjct: 2087 TGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEEDLLTD 2146

Query: 824  ---EPTEENAEP----PLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
                  EE AEP    P  + +   I   +E+   KL  +V  +P P I W +  E I P
Sbjct: 2147 KSISTLEEYAEPIEYAPQIVKQLPTIIHSQERELTKLEVKVLAHPKPQIRWLKAGEEIIP 2206

Query: 876  SETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
            S+    +NFD     L+I ++  + DSG+    A N+ G +       + VE++   K  
Sbjct: 2207 SDEFQIENFDDGTSILIINDIYPD-DSGEITFEAHNALGVAM--TTTELVVEEIVGTKAY 2263

Query: 935  QKS---YETEEGKTVILECQT 952
            +K       EE K  + E  T
Sbjct: 2264 RKPEWVQHMEELKEALQESST 2284



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 101/457 (22%), Positives = 174/457 (38%), Gaps = 31/457 (6%)

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
            +K V E T+K    S  + R LI    T   Q   T +       +K KV+    PP IV
Sbjct: 1572 QKRVQEVTDKIAEESVREDRQLIE---TTQQQISETKIQEQTVKISKPKVQ----PPNIV 1624

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
            +  +    +    V L    +  P P  +W  N  ++        ++    A+L I  V+
Sbjct: 1625 EKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATLEIATVQ 1684

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI---LEID-SSSINICWDEPENT 1407
                GIY    +N  G A  + N+ + +KP     P     L+I+ +    I     +  
Sbjct: 1685 PYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLKIELNEQKTIATVTCQVA 1744

Query: 1408 GNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-----SIQNLKTNSSYRFRAYAVNEVDI 1461
            G  T  + ++ +  EI   E   ++   + +T     ++++ K N    F   A N+   
Sbjct: 1745 GIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGK 1804

Query: 1462 SDASETTEYYKVIKETKIQS---PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            +          V+ E    S   P + +PL+         +   C F G P+P V W+R+
Sbjct: 1805 AVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRN 1864

Query: 1519 GKKLKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             K++   +      T E                 Y+    N+ G+ ++S  V I      
Sbjct: 1865 SKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSASVAISDATDT 1924

Query: 1574 TISN-----EDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
              +      E +  K     E  ++ A +E  P     W+K G  +++  E  I TKE  
Sbjct: 1925 DEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNEQRIVTKENR 1984

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
            S++ I+   R  +  YT  A N AG+ +   T++  D
Sbjct: 1985 SILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLD 2021



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 150/710 (21%), Positives = 287/710 (40%), Gaps = 80/710 (11%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            +EP QV E +  ++  +   +I        PR T    K+    K +  K +  T +   
Sbjct: 1431 EEPAQVAETIVDIVAEEVLDLIPDLA----PRETAKKRKSRNK-KHVVFKEELSTFA--- 1482

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV--KEKGT 849
            ++P++ +++     + E  + I+ +S  IT+  P  + A  P+   + +E T   +++  
Sbjct: 1483 MEPEEEEEQEEDEAEEEQVQEISRSS--ITLTRPDSKPAPVPVEELKMEEQTTEFRKEME 1540

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            +++ + + +       +  +++ +   E ITQ    + ++ V   +  E    D + + +
Sbjct: 1541 VRVQSNIVKKEKKRRVFIDDSQPLPELEIITQ----KRVQEVTDKIAEESVREDRQLIET 1596

Query: 910  NSAGKSSHGAR---VTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHTV--STKWY 961
                 S    +   V I   KV     V+ LQ     E  K V+L C+       + +WY
Sbjct: 1597 TQQQISETKIQEQTVKISKPKVQPPNIVEKLQPQI-CEPDKPVLLRCRIEGVPFPTVQWY 1655

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKET-- 1015
             N   +       +                  VG+  C  K+      +   +VV+E   
Sbjct: 1656 FNDTVLFASSEYIMNVVEDVATLEIATVQPYHVGIYTCEAKNVAGVAISKANIVVQEKPE 1715

Query: 1016 ---IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNK---YDFEK 1067
                P F+  L+    ++K +A +  ++    T  V W RD  EII+ ++ +   Y  E+
Sbjct: 1716 HGEAPRFVVPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEER 1775

Query: 1068 RGHIRKLYIRNT--------SVHDEGEYSCILRDESCTAEVTVVE------LPPEIITRL 1113
             GH+R L +++         +V  E ++   +   +   +  V+E      + P+I+  L
Sbjct: 1776 TGHVR-LTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPL 1834

Query: 1114 QNQKVNKGNKATFEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLD 1171
            + Q V  G+   FE   T +    V+WF++  EI +    + +T +    +L+I      
Sbjct: 1835 EAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQ 1894

Query: 1172 DAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LVP---ANTDAYLTVEIPD 1222
              G+Y      E G +K +A + + + +     + P FI  LVP   A  +  +     +
Sbjct: 1895 RGGKYEITVTNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVE 1954

Query: 1223 E--TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKST 1276
               T    W+K+ + I+ T +  +++   +  LII   T  D   YTC    V     ST
Sbjct: 1955 SYPTSTFQWFKEGAAIKSTNEQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTST 2014

Query: 1277 TKLKV-------EVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
              ++        EV E+  P+ ++  +  R+  G  +TL     A P P   W  N+++I
Sbjct: 2015 ATVQTLDTIETEEVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLI 2074

Query: 1329 KKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            ++ K  +   DS     L+I +V   D G Y     N  G A     V +
Sbjct: 2075 QETKDKQVQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNV 2124



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 132/654 (20%), Positives = 243/654 (37%), Gaps = 71/654 (10%)

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLK----SMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
            E S   +   +   K  P  +E LK    +   R+   V + + +V   +    +  +++
Sbjct: 1503 EISRSSITLTRPDSKPAPVPVEELKMEEQTTEFRKEMEVRVQSNIVKKEKKRRVFIDDSQ 1562

Query: 774  PVKALPTKSDGDTHSITILKPKKVKDEGVYT---LKAENSEGIAETSAVITVEEPTEENA 830
            P+  L   +      +T     K+ +E V     L     + I+ET       + ++   
Sbjct: 1563 PLPELEIITQKRVQEVT----DKIAEESVREDRQLIETTQQQISETKIQEQTVKISKPKV 1618

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            +PP  + + Q    +    + L  R+   P P++ WY N+ ++  S     N   +   L
Sbjct: 1619 QPPNIVEKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATL 1678

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-----EKVTFVKHLQKSYETEEGKT 945
             I  V      G Y C A N AG +   A + +       E   FV  L+   E  E KT
Sbjct: 1679 EIATV-QPYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLK--IELNEQKT 1735

Query: 946  V-ILECQTS--HTVSTKWYHNKKEISGMDHREI---IQEGRXXXXXXXXXXXXDVGVIKC 999
            +  + CQ +   T   +W  ++ EI   +  EI    +E              +V V+  
Sbjct: 1736 IATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFT 1795

Query: 1000 IVKDQETSTML---------VVKE------TIPEFIRKLQDFEVKEKDVAILEVEINSET 1044
            +V + +    +         VV E        P+ ++ L+   V+     + E     + 
Sbjct: 1796 VVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQP 1855

Query: 1045 ADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAE 1099
               V W R+ + I  ++ +       +  +L IR  +    G+Y   + +E+     +A 
Sbjct: 1856 KPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSAS 1915

Query: 1100 VTVVEL-------PPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNH 1151
            V + +         P  I  L  + + +      E  + +   +  +WFK+G+ I+ +N 
Sbjct: 1916 VAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNE 1975

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFI--- 1206
             ++     +  L I      D G Y+C   N     T+  TV+      T  + E+I   
Sbjct: 1976 QRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISPR 2035

Query: 1207 ----LVPANT--DAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKR-TLIIR 1256
                + P        LT+E     +    V WY    +I++T+   +  D   R  L I 
Sbjct: 2036 FLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSIS 2095

Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            +   +D+ EYTCV  +       +  V   P + V    ++   R S+  LL D
Sbjct: 2096 EVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQF---RSSEEDLLTD 2146



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 18/209 (8%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534
            ++P    PLK    E      +TC   G+P PKV W RD  ++     +  +  YE R  
Sbjct: 1718 EAPRFVVPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTG 1777

Query: 1535 XXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQ------KPVITISN--EDIK-Q 1582
                            +  +A N  G+      V IQ       KP        + ++ Q
Sbjct: 1778 HVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQ 1837

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSS 1641
              + G   +      G P P V W++N  ++ E ++E  ITT+E  S + I+ + R    
Sbjct: 1838 VVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGG 1897

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
            KY I  +N AG +    ++ + D     E
Sbjct: 1898 KYEITVTNEAGQAKSSASVAISDATDTDE 1926



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 28/82 (34%), Positives = 39/82 (47%)

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            L+   IEG+P P V WY N   L    EY +   E  + + I  ++  H   YT EA N 
Sbjct: 1639 LLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATLEIATVQPYHVGIYTCEAKNV 1698

Query: 1651 AGTSSVEVTLKVYDKPSKPEGP 1672
            AG +  +  + V +KP   E P
Sbjct: 1699 AGVAISKANIVVQEKPEHGEAP 1720



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 64/298 (21%), Positives = 112/298 (37%), Gaps = 17/298 (5%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLT 1346
            P+IV       ++ GS +     +   P+P  +W  NSK I+++ +    + +   + L 
Sbjct: 1828 PQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLE 1887

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILE------IDSSSIN 1398
            I++V     G Y++ + N  G A    +V I D         P  +E      I  + + 
Sbjct: 1888 IRRVTRQRGGKYEITVTNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVC 1947

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL--KTNSSYRFRAYAV 1456
            I     E+   ST  ++        T E   V    ++   I++   +   +Y  RA  V
Sbjct: 1948 ILEASVESYPTSTFQWFKEGAAIKSTNEQRIVTKENRSILIIESFTRRDTGAYTCRAENV 2007

Query: 1457 NEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
                 S A+ +T +  +  + T+  SP   + +K       E + L C    +P PKV W
Sbjct: 2008 AGSVTSTATVQTLDTIETEEVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHW 2067

Query: 1516 YRDGK-----KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            Y + +     K K  +     R               Y C+A N  GE      V ++
Sbjct: 2068 YHNAQLIQETKDKQVQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVE 2125



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 62/268 (23%), Positives = 105/268 (39%), Gaps = 32/268 (11%)

Query: 1416 VVEYQE---IDTTEWIS---VKNITKTQTSIQNLK-TNSSYRFRAYAVNEVDISDASETT 1468
            +VE +E   I T E+ S   ++ +T+ +     +  TN + + ++ A   V ISDA++T 
Sbjct: 1868 IVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSA--SVAISDATDTD 1925

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-- 1526
            E     K  +   P V K +        E   L       P     W+++G  +K+    
Sbjct: 1926 E----AKAPRFIEPLVPKLIAEA-----EVCILEASVESYPTSTFQWFKEGAAIKSTNEQ 1976

Query: 1527 --ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG----IQQKPVITISN--- 1577
               T ENR               Y C A N  G V ++  V     I+ + V    +   
Sbjct: 1977 RIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISPRF 2036

Query: 1578 -EDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKE 1634
             E IK    + G+   +   +  +P P+V WY N   ++  K+  +        V+ I E
Sbjct: 2037 LETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSISE 2096

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            +      +YT  A+N  G +    T+ V
Sbjct: 2097 VFPEDKGEYTCVATNKIGEAICRATVNV 2124



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 47/219 (21%), Positives = 95/219 (43%), Gaps = 17/219 (7%)

Query: 167 KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNE-VPEKINVPDDKETSQTPTSFN 225
           +P   +P + ++   K  PK  +E+E    K   I  + +PE  + P+ +   + P    
Sbjct: 556 RPLPEEPKEEVV--LKPIPKPTKENEPKETKEQTIKPKPMPELDDKPEPELELEKPAVPE 613

Query: 226 KRSKLTPIKIERKEME---VSTPQHAETVDGPQFXXXXXXXXXX--XXXXETSLVKLPKF 280
           + + L P +  +K +E   + TP   E V+                    E SL  +PK 
Sbjct: 614 EDTSLPPWRRGKKSVEKKPLPTPAEPEKVEQVTLKPTPRQKKELPKEAIEEVSLKPVPK- 672

Query: 281 QLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTE 340
             K  ++ + +  PE ++     +   K+     + + +   ++K  F P ++P+VEK E
Sbjct: 673 --KPVVEEVATAEPEEVEEKTVKIVKKKK----PKAVTQQESLEKLEFTPTEVPEVEKME 726

Query: 341 LEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379
           + + L   + I   ++ E    + +Q  +  P+E+VPE+
Sbjct: 727 MPEKLEEVKPIEPEQEPEKPSWRRQQ--KPKPQEEVPEE 763



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 48/228 (21%), Positives = 94/228 (41%), Gaps = 16/228 (7%)

Query: 152 TLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV 211
           T  K   F  +ED S   + Q  Q +  ++K   + +     P  +   ++    E    
Sbjct: 336 TTPKPVEFTEREDSSTLKLEQTEQELSLDSKPTEQPVGWRRGPKERKPVVEPATEEP--A 393

Query: 212 PDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271
           P+D+  +Q P     R K  P +   K+ E    +       P+               E
Sbjct: 394 PEDQPETQLPPWMRGR-KPGPKRELPKQPEPEKVEQVMLKPTPR----QKKELPKEAIEE 448

Query: 272 TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331
            SL  +PK   K  ++ + +  PE ++     +   K+     +++ +   ++K  F P 
Sbjct: 449 VSLKPVPK---KPVVEEVATAEPEEVEEKTVKIVKKKK----PKSVTQQESLEKLEFTPT 501

Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379
           ++P+VEK E+ + L   + I   ++ E    + +Q L+  P+E+VPE+
Sbjct: 502 EVPEVEKMEMPEKLEEVKPIEPEQEPEKPSWRRQQKLK--PQEEVPEE 547



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 56/233 (24%), Positives = 94/233 (40%), Gaps = 26/233 (11%)

Query: 185  PKLIEESEQPIAKTSEIDNEVP-EKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVS 243
            P++ E+ E  + KT  I  EV  E   VP+     +TP       K  P++ E +E +  
Sbjct: 1146 PEIPEQEEVQLEKTEHIPEEVQKEPETVPEQPPWRRTP-------KPKPVETEEEEKKWP 1198

Query: 244  TPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISY 303
            T +    V+ P+               E      P+ Q+  + K+    P E I  +  +
Sbjct: 1199 TGKRRPPVEEPKEEVVLKPIPKPTKDVEPQ----PEQQITIKPKHPEPTPKEEIPEVTPW 1254

Query: 304  M-GSIKQNGILSRNIKEAAKVKKQVFVP-PK----LPDVEKTELEQPLFSYED--IVESK 355
              G  ++  +     KE  K K++     PK    L  + K   E+P    E+  IV  K
Sbjct: 1255 RRGKKEKPPVEEEEPKEWPKGKRRPLPETPKEEVVLKPIPKPSKEEPPKPAEEPTIVLPK 1314

Query: 356  KDENEIIQEKQT-----LEELPKEDVP-EQYTITPRKSSAQKIDEIVDEVTIK 402
                E  + KQ      ++ELPKE+ P E+ T+ P     +    + +E+ +K
Sbjct: 1315 PTVQEPEEPKQAPWRRGMKELPKEETPKEEITLKPIPKREEPEQTVQEEIILK 1367



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 47/219 (21%), Positives = 92/219 (42%), Gaps = 17/219 (7%)

Query: 167 KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNE-VPEKINVPDDKETSQTPTSFN 225
           +P   +P + I+   K  PK  +E+E    K   I  + + E  + P+ +   + P    
Sbjct: 772 RPLPEEPKEEIV--LKPIPKPTKENEPKETKEQTIKPKPISELDDKPEPELELEKPAVPE 829

Query: 226 KRSKLTPIKIERKEME---VSTPQHAETVDGPQFXXXXXXXXXX--XXXXETSLVKLPKF 280
           + + L P +  +K +E   +  P   E V+                    E SL  +PK 
Sbjct: 830 EDTSLPPWRRGKKPVEKKPLPPPAEPEKVEQVMLKPTPRQKKELPKEAIEEVSLKPVPK- 888

Query: 281 QLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTE 340
             K  ++ I    PE ++     +   K+     + + +   ++K  F P ++P+VEK E
Sbjct: 889 --KPVVEEIAPTEPEEVEEKTVKIVKKKK----PKAVTQQESLEKLEFTPTEVPEVEKME 942

Query: 341 LEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379
           + + L   + I   ++ E    + +Q  +  P+E+VPE+
Sbjct: 943 MPEKLEEVKPIEPEQEPEKPSWRRQQ--KPKPQEEVPEE 979



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 9/96 (9%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            P P++ W K G ++    E+ I    + TS++ I ++    S + T EA N  G +    
Sbjct: 2191 PKPQIRWLKAGEEIIPSDEFQIENFDDGTSILIINDIYPDDSGEITFEAHNALGVAMTTT 2250

Query: 1659 TL--------KVYDKPSKPEGPVIMREISRESVTIE 1686
             L        K Y KP   +    ++E  +ES T E
Sbjct: 2251 ELVVEEIVGTKAYRKPEWVQHMEELKEALQESSTEE 2286


>UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 621

 Score =  155 bits (376), Expect = 1e-35
 Identities = 164/651 (25%), Positives = 271/651 (41%), Gaps = 65/651 (9%)

Query: 757  QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            ++ G P+P I W K++KPVK    +      D HS+TI+      D   YT KA N  G 
Sbjct: 1    KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASP-DDTAKYTCKATNKSGT 59

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
               +  + +  P     +P   +N   EI V E  +++L   ++  P   + WY+++ ++
Sbjct: 60   TTRNINVDISAPII--IKP---LN--DEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLL 112

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
               E I  + DG+   L+I + + + D  +YKCV +N AG       + I  E   F K 
Sbjct: 113  EEDERIMYDTDGDQHTLIIQSAELD-DEAEYKCVVTNIAGSVDVKTELIIAPE---FQKE 168

Query: 934  LQKS-YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990
             +KS ++   G  V L+   +   T   +W+ + K + G    E+  +            
Sbjct: 169  PEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGK 228

Query: 991  XXDVGVIKCIVKD---QETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
              D G    + +    ++T T  V +K   PEF +K+Q  +V E D  + E         
Sbjct: 229  PDDSGKYTVVAESPAGRDTRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE--------- 279

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV 1102
                 +G  +         ++ G +  L I N    D G Y C   ++    +  AE+ +
Sbjct: 280  -----EGRFLIVD------DEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 328

Query: 1103 VEL--PPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDG 1158
             EL   PE       Q  + + +  T E+ +T K    V W KD   +   + I +   G
Sbjct: 329  EELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKG 388

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEE-PSINFTLRLPEFILVPANTD 1213
                + I     +D+G Y CE  N    +  T I+ VEE P I  +L+  E +       
Sbjct: 389  DSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEEL---EGNP 445

Query: 1214 AYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              LT +       V  W+K  + + DT+++  I +    TLII+    DD   Y CV  +
Sbjct: 446  VTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASN 505

Query: 1273 --AKSTTK--LKVEVVEFPPKIVDYEREYRI--KRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
               K T +  LKV    FPP+I   ER  +I      ++ + V     P+P+ +W  + K
Sbjct: 506  QVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGK 565

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             I++           + +L I   E  DAG Y    +N  G +   ++V I
Sbjct: 566  PIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI 616



 Score =  147 bits (356), Expect = 3e-33
 Identities = 154/576 (26%), Positives = 232/576 (40%), Gaps = 59/576 (10%)

Query: 639  KPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            KP    +D  EG  + LEC +   P+  + W      +  DE I    + D H     L 
Sbjct: 75   KPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQH----TLI 130

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILS 755
            I + +   E  Y  V  N  G   +   L I      P    EP KS   V  G+ V L 
Sbjct: 131  IQSAELDDEAEYKCVVTNIAGSVDVKTELIIA-----PEFQKEPEKSTFDVNTGDDVSLD 185

Query: 756  AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              V G P P + W K++KPVK    L  K+  D HS+ I K  K  D G YT+ AE+  G
Sbjct: 186  LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKI-KGGKPDDSGKYTVVAESPAG 244

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
                +  + ++       E P F  + Q + V E G  K VA   R              
Sbjct: 245  RDTRTYEVNIK------GEKPEFKQKMQPLQVLE-GDEK-VAEEGRF------------- 283

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--F 930
                  I  + +G+   L+I N    +DSG Y C A+N  GK++  A + I+   V   F
Sbjct: 284  -----LIVDDEEGDLFSLIIGNA-KPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEF 337

Query: 931  VKH--LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
             +    Q +   ++  T+ L           W  + K ++  D   I  +G         
Sbjct: 338  AEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMA 397

Query: 989  XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                D G  KC  K++    T T +V  E  PE    LQ+ E  E +   L  +     A
Sbjct: 398  VTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFTGTPA 457

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVT 1101
             V             ++Y+F + G    L I+ T   D+  Y C+  ++    +C  ++ 
Sbjct: 458  PVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLK 517

Query: 1102 VVE--LPPEIITRLQNQKVNKGNKATFEIELT-KGDAL--VRWFKDGSEIQFSNHIQLTI 1156
            V E   PPEI    + +K+    K    I +T  G+    V+WFKDG  I+ S+ + +  
Sbjct: 518  VTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRP 577

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             G    L I+  + +DAG Y+CE  N   T+  T++
Sbjct: 578  RGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTID 613



 Score =  126 bits (304), Expect = 7e-27
 Identities = 127/543 (23%), Positives = 214/543 (39%), Gaps = 35/543 (6%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPS 1195
            ++WFKD   ++ S  I++        L I     DD  +Y+C+  N   T    +  + S
Sbjct: 10   IQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDIS 69

Query: 1196 INFTLR-LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
                ++ L + I V       L   I       V WYK   ++E+ E+    +D  + TL
Sbjct: 70   APIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTL 129

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQ 1312
            II+    DD+ EY CV+ +   +  +K E++  P    + E+  + +  G DV+L +   
Sbjct: 130  IIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTGDDVSLDLTVT 189

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
              P P  EW  + K +K  +  +        SL IK  +  D+G Y +  E+  G     
Sbjct: 190  GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDTRT 249

Query: 1373 MNVTIL-DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
              V I  +KP    K   L++      +  +E          + +V+ +E D    I   
Sbjct: 250  YEVNIKGEKPEFKQKMQPLQVLEGDEKVA-EEGR--------FLIVDDEEGDLFSLI--- 297

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
                    I N K   S  +   A N+        T E    I+E  +     E+    +
Sbjct: 298  --------IGNAKPLDSGVYICQATNDT----GKATAEAEIQIEELLVAPEFAEEEATQL 345

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXX---XXXXXXXXXXXX 1547
            T   ++D+ L     G P+P+V W +D K L +  +   +++                  
Sbjct: 346  TLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGT 405

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            YKC A N  G    + +V +++ P IT S +++++    G+   +T    G P P   W+
Sbjct: 406  YKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELE--GNPVTLTCKFTGTPAPVAEWF 463

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            K    L +   Y    +  +  + IK   R     Y   ASN  G  +    LKV +K  
Sbjct: 464  KASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMF 523

Query: 1668 KPE 1670
             PE
Sbjct: 524  PPE 526



 Score =  121 bits (291), Expect = 3e-25
 Identities = 140/641 (21%), Positives = 255/641 (39%), Gaps = 57/641 (8%)

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-VE 1104
            ++ W +D + +KP + K   + R  I  L I   S  D  +Y+C   ++S T    + V+
Sbjct: 9    EIQWFKDDKPVKPSQ-KIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVD 67

Query: 1105 LPPEIITRLQNQKVN--KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            +   II +  N +++  +G+    E  ++ G DA V W+KD   ++    I    DG + 
Sbjct: 68   ISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQH 127

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT--DAYLTVE 1219
             L I   +LDD  EY C V N   +  +  E        + PE      NT  D  L + 
Sbjct: 128  TLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTGDDVSLDLT 187

Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
            +  + T  V W+K    ++ T +  + +   + +L I+    DD  +YT V      + T
Sbjct: 188  VTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDT 247

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
               +V +    P+     +  ++  G +   + +   F   +DE                
Sbjct: 248  RTYEVNIKGEKPEFKQKMQPLQVLEGDEK--VAEEGRFLIVDDE---------------- 289

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
              +    SL I   +  D+G+Y  +  N+ G A  E  + I +    P      E +++ 
Sbjct: 290  --EGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAP---EFAEEEATQ 344

Query: 1397 INICWDEPEN-----TGN-STIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSY 1449
            + +  D+        TG     +++  + + +   + I + +   +    I  +  N S 
Sbjct: 345  LTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSG 404

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             ++  A N+  ++     T  + V  E   ++P + + L+ +       + LTC F G P
Sbjct: 405  TYKCEAKNKAGVN-----TRTFIVNVE---EAPEITESLQEMEELEGNPVTLTCKFTGTP 456

Query: 1510 QPKVTWYRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             P   W++    L T    YE     +                YKC+A N  G+V     
Sbjct: 457  APVAEWFKASTPL-TDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGD 515

Query: 1565 VGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            + + +K   P IT      K      +E ++   I G P P+V W+K+G  +      NI
Sbjct: 516  LKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNI 575

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
              +  T  + I   +   +  YT EA N  GTSS  + +++
Sbjct: 576  RPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI 616



 Score =  118 bits (285), Expect = 1e-24
 Identities = 142/652 (21%), Positives = 248/652 (38%), Gaps = 62/652 (9%)

Query: 656  RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
            ++   P+P+I W    + + P + I V    D+H     L I          YT  A N+
Sbjct: 1    KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHS----LTIVGASPDDTAKYTCKATNK 56

Query: 716  EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNN-- 772
             G  +  I + I       P +I+PL   I V +G+SV L   + G P   + W K++  
Sbjct: 57   SGTTTRNINVDISA-----PIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYL 111

Query: 773  -KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             +  + +   +DGD H++ I++  ++ DE  Y     N  G  +    + +    ++  E
Sbjct: 112  LEEDERIMYDTDGDQHTL-IIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPE 170

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
               F        V     + L   VT  P P + W+++++ +  +  +      +   L 
Sbjct: 171  KSTF-------DVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLK 223

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
            I     + DSG Y  VA + AG+ +    V I  EK  F + +Q   +  EG   + E  
Sbjct: 224  IKGGKPD-DSGKYTVVAESPAGRDTRTYEVNIKGEKPEFKQKMQ-PLQVLEGDEKVAEEG 281

Query: 952  TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTM- 1009
                V                    +EG             D GV  C    D   +T  
Sbjct: 282  RFLIVDD------------------EEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAE 323

Query: 1010 --LVVKETI--PEFI-RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKY 1063
              + ++E +  PEF   +     + E D   LE+ +  +   +V W +D + +  + ++ 
Sbjct: 324  AEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPL-TEDDRI 382

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVNK 1120
              + +G    + I   + +D G Y C  +++   +    +  VE  PEI   LQ  +  +
Sbjct: 383  IIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELE 442

Query: 1121 GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178
            GN  T   + T   A +  WFK  + +  ++  +   +G    L I     DD   Y C 
Sbjct: 443  GNPVTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCV 502

Query: 1179 ---EVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
               +VG   C   L V E    P I    R  + +L+           + +   DV W+K
Sbjct: 503  ASNQVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFK 562

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
                I  + +  +       TL I     +D   YTC   +   T+   ++V
Sbjct: 563  DGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDV 614



 Score =   99 bits (238), Expect = 7e-19
 Identities = 133/552 (24%), Positives = 225/552 (40%), Gaps = 49/552 (8%)

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            ++T  P P I W+++++ + PS+ I  ++  +   L I     + D+  Y C A+N +G 
Sbjct: 1    KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPD-DTAKYTCKATNKSGT 59

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH 972
            ++    + +D+     +K L    +  EG +V LEC  S     +  WY +   +   + 
Sbjct: 60   TTRN--INVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDER 117

Query: 973  REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI-PEFIRKLQD--FEVK 1029
                 +G             D    KC+V +   S  +  +  I PEF ++ +   F+V 
Sbjct: 118  IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVN 177

Query: 1030 EKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
              D   L++ +  + T  V W +D + +K  + + + + +     L I+     D G+Y+
Sbjct: 178  TGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTR-RLEVKAKDDEHSLKIKGGKPDDSGKYT 236

Query: 1089 CILRD----ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGS 1144
             +       ++ T EV +    PE   ++Q  +V +G++   E    +G  L+   ++G 
Sbjct: 237  VVAESPAGRDTRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE----EGRFLIVDDEEGD 292

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLP 1203
               FS      I G  + L        D+G Y C+  N   T   T E E  I   L  P
Sbjct: 293  --LFS-----LIIGNAKPL--------DSGVYICQATND--TGKATAEAEIQIEELLVAP 335

Query: 1204 EFILVPANTDAYLTVEIPDETLD--VTWYKKKSV--IEDTEKFT----LISDVKKRTLI- 1254
            EF    A T   L +E  D TL+  VT   K  V   +D +  T    +I D K  + I 
Sbjct: 336  EFAEEEA-TQLTL-IEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIV 393

Query: 1255 -IRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
             I   T +D   Y C   + A   T+  +  VE  P+I +  +E     G+ VTL   + 
Sbjct: 394  DIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFT 453

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
              P P  EW   S  +      +   +  S +L IK     D   YK    N  G     
Sbjct: 454  GTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCR 513

Query: 1373 MNVTILDKPSPP 1384
             ++ + +K  PP
Sbjct: 514  GDLKVTEKMFPP 525



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 76/300 (25%), Positives = 133/300 (44%), Gaps = 22/300 (7%)

Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           + P F+++   Q  + E  D+ LE  +   P+P++ W    + +  D+ I +  + D   
Sbjct: 333 VAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDS-- 390

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
            C ++ I  V     GTY   A N+ G  +   ++ ++    E P++ E L+ M   +G 
Sbjct: 391 -C-IVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE----EAPEITESLQEMEELEGN 444

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKA 807
            V L+ +  G P P   W K + P+          +GD++++ I+K     D+  Y   A
Sbjct: 445 PVTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTL-IIKTTVRDDDDTYKCVA 503

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            N  G       + V   TE+   P +    R ++I + EK  + +   +  NP P + W
Sbjct: 504 SNQVGKVTCRGDLKV---TEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKW 560

Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
           +++ + I  S  +     G+   L I   + E D+G Y C A N  G SS     TIDV+
Sbjct: 561 FKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPE-DAGSYTCEAQNKMGTSS----TTIDVQ 615



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 89/328 (27%), Positives = 152/328 (46%), Gaps = 47/328 (14%)

Query: 504 EEQSMAPIFVEKLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYD 561
           EE  +AP F E+   + T  +   +  E  V G P+P++ W +     KP ++D ++  D
Sbjct: 329 EELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDN---KPLTEDDRIIID 385

Query: 562 DDNVATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
               + +V I  V P D+GT+ C AKN AG   +T   IV     +   E+T        
Sbjct: 386 HKGDSCIVDIMAVTPNDSGTYKCEAKNKAGV--NTRTFIVNV---EEAPEIT-------- 432

Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
                 + LEG P T                 L C+    P P   W FK    + D + 
Sbjct: 433 ESLQEMEELEGNPVT-----------------LTCKFTGTPAPVAEW-FKASTPLTDTDR 474

Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
              IE +   Y  ++K T   +  + TY  VA N+ G+ +    LK+ T +  PP++  P
Sbjct: 475 YEFIE-EGDSYTLIIKTT--VRDDDDTYKCVASNQVGKVTCRGDLKV-TEKMFPPEITRP 530

Query: 741 --LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPK 795
              + +++ + E ++++  ++GNPRP + W K+ KP++    L  +  GDT+++ I    
Sbjct: 531 ERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNI-HTT 589

Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVE 823
           + +D G YT +A+N  G + T+  + +E
Sbjct: 590 EPEDAGSYTCEAQNKMGTSSTTIDVQIE 617



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 6/158 (3%)

Query: 1507 GVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            G P+P++ W++D K +K +   +  Y ++                Y C A N  G    +
Sbjct: 4    GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRN 63

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
              V I    +I   N++I      GD   +  VI G P  +V+WYK+   LE D+     
Sbjct: 64   INVDISAPIIIKPLNDEIDVLE--GDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYD 121

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            T      + I+  +    ++Y    +N AG+  V+  L
Sbjct: 122  TDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 159



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
           ++ G P+P+I WF+    +KPSQ  ++ Y DD + +L I    P+D   +TC A N +G 
Sbjct: 1   KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDD-IHSLTIVGASPDDTAKYTCKATNKSGT 59

Query: 592 ASSTTELIVEAPL 604
            +    + + AP+
Sbjct: 60  TTRNINVDISAPI 72



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 509 APIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
           API ++ L  +    +G +V+ EC + G P  Q+ W++   +++  +   MY  D +  T
Sbjct: 70  APIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERI-MYDTDGDQHT 128

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           L+I+    +D   + CV  N AG     TELI+
Sbjct: 129 LIIQSAELDDEAEYKCVVTNIAGSVDVKTELII 161



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 2/143 (1%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVI 1605
            Y C A ND G+      + I++  V    + E+  Q   + D+ +   + + G P PEV 
Sbjct: 309  YICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVH 368

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W K+   L  D    I  K  + ++ I  +  + S  Y  EA N AG ++    + V + 
Sbjct: 369  WTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEA 428

Query: 1666 PSKPEGPVIMREISRESVTIEWK 1688
            P   E    M E+    VT+  K
Sbjct: 429  PEITESLQEMEELEGNPVTLTCK 451



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
           G PRP + WF+    I+ S    +    D   TL I    PEDAG++TC A+N  G +S+
Sbjct: 552 GNPRPDVKWFKDGKPIRQSSRLNIRPRGDTY-TLNIHTTEPEDAGSYTCEAQNKMGTSST 610

Query: 595 TTELIVEAPLS 605
           T ++ +E  +S
Sbjct: 611 TIDVQIEGEVS 621



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 49/192 (25%), Positives = 91/192 (47%), Gaps = 18/192 (9%)

Query: 434 DEAINLVEGE--RLYILDTSNQD---WWYVQKHLTEEKGWVPAQYLMDENNYTQYLQK-K 487
           ++ I+++EG+  RL  + +   D    WY   +L EE   +   Y  D + +T  +Q  +
Sbjct: 78  NDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERI--MYDTDGDQHTLIIQSAE 135

Query: 488 LNEKIDKLPVFEK-----PTSEEQSMAPIFVEKLRPKHTPD---GSTVQFECQVEGYPRP 539
           L+++ +   V            E  +AP F +K   K T D   G  V  +  V G P P
Sbjct: 136 LDDEAEYKCVVTNIAGSVDVKTELIIAPEF-QKEPEKSTFDVNTGDDVSLDLTVTGKPTP 194

Query: 540 QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
           ++ WF+    +K ++  ++   DD   +L I+   P+D+G +T VA++ AG  + T E+ 
Sbjct: 195 KVEWFKDDKPVKGTRRLEVKAKDDE-HSLKIKGGKPDDSGKYTVVAESPAGRDTRTYEVN 253

Query: 600 VEAPLSDHGSEM 611
           ++    +   +M
Sbjct: 254 IKGEKPEFKQKM 265



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 12/168 (7%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654
            I G P PE+ W+K+   ++  ++  +  ++    + I       ++KYT +A+N +GT+ 
Sbjct: 2    ITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTT 61

Query: 1655 ---SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
               +V+++  +  KP   E  V+  +  R    I   P       +   Y +E+ E    
Sbjct: 62   RNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYK-DDYLLEEDER--- 117

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
                + D D D  T  IQ    + E  ++ +  N  G S  +++E I+
Sbjct: 118  ---IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG-SVDVKTELII 161


>UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|Rep:
            CG33484-PD, isoform D - Drosophila melanogaster (Fruit
            fly)
          Length = 3651

 Score =  153 bits (372), Expect = 4e-35
 Identities = 137/536 (25%), Positives = 230/536 (42%), Gaps = 69/536 (12%)

Query: 472  QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
            Q L D+ +  + + + + + I    +F    +E +  +P+F   L+   + +G    FEC
Sbjct: 1343 QTLRDQVDQQRIVTENIRKDIQVNSIF----TELRYASPLFTRPLKDAVSREGDRFVFEC 1398

Query: 532  QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
            +V G P P + WF+    I+ + D++  +D   +  LVI E F  D+  F+C A N  G 
Sbjct: 1399 EVTGTPEPAVEWFKDGISIQTNSDYKTTFDK-GICRLVIEETFAADSARFSCRASNLVGT 1457

Query: 592  ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
              +   L V     ++ +E+ +                  +PP   +  ++    EGS  
Sbjct: 1458 CDTNATLSVR----ENAAEVQL------------------VPPRILRFLQSGKATEGSSF 1495

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
               C +  +P P + W FK ++ + D    V   ++     + LK   V    +  YT  
Sbjct: 1496 QFACVVAGVPLPTVQW-FKNDKCIDDSPDYVISYNNGE---ATLKFEEVFLEDDAVYTCS 1551

Query: 712  AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            A N  G       L ++  E  E P    PL + + R G+ + L A V G PRP + W  
Sbjct: 1552 ASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLH 1611

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE--PTE 827
            N KP +  P  S  +   +T++ P+    D G Y L A+N  G A TS  + V+   P E
Sbjct: 1612 NGKPFQ--PRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNE 1669

Query: 828  -------ENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
                    + EP  P      +++++ E   ++L   +   P P + WY N   +  S  
Sbjct: 1670 TSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESAD 1729

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI------------DVE 926
            +   F G+   L+I  V  E D+G YK VA NSAG++S    + +              E
Sbjct: 1730 VQLLFQGDRCSLIIQEVYQE-DAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAE 1788

Query: 927  KVTFVKHLQKSYE-------TEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973
            + +  K  Q  +E        +EG+ V+LE Q S    ++ +W+   KE+  +D R
Sbjct: 1789 RQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQ-LDQR 1843



 Score =  144 bits (348), Expect = 3e-32
 Identities = 200/791 (25%), Positives = 313/791 (39%), Gaps = 121/791 (15%)

Query: 501  PTSEEQSMAPIFVEKLRPKHTPD------------GSTVQFECQVEGYPRPQITWFRQTA 548
            P   E   A + VE L P   P             G  ++ E  V G PRP++ W     
Sbjct: 1555 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNG- 1613

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608
              KP Q     Y+   V TL+I + +P DAG++   AKN AG A ++  +IV+  L +  
Sbjct: 1614 --KPFQPRDSKYEYGRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 1670

Query: 609  SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
            S+  +            A  +E I P      K   + EG  + L+C +V  PEP++ W 
Sbjct: 1671 SDSEM------------ASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWY 1718

Query: 669  FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
                 +    ++ +  + D    CS++ I  V +   G Y VVA+N  GEAS    LK+ 
Sbjct: 1719 HNERPVKESADVQLLFQGDR---CSLI-IQEVYQEDAGHYKVVAINSAGEASSSCELKVT 1774

Query: 729  T-GEKEP-----------PQVIEP-----LKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
               + EP           P+  +P     L  ++  +GE V+L  Q  G+   T  W   
Sbjct: 1775 PLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLT 1834

Query: 772  NKPVKA---LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE---- 823
            NK ++    + T+SD +      IL      D+GVYT+K  N  G A+  + + V+    
Sbjct: 1835 NKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNA 1894

Query: 824  -EPTEENAEPPLFINR-----FQEITVKEKG----TIKLVARVTRNPVPSITWYRNNEII 873
             E    +      I R     F+E+   ++G     IK    V   P P + W+ N++ +
Sbjct: 1895 PENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPV 1954

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTF 930
                 +     GE   L I  +  +   G   CVA N AGK++  A + I    +   + 
Sbjct: 1955 HGHNFLVST-SGERQVLTIQKLTHDA-VGKISCVAENEAGKATCVAFLNIRGSGLPASSD 2012

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS-------------TKWYHNKKEIS------GMD 971
            V+ + + + TE  + V ++ QT  T S             T+ +H+   I       G  
Sbjct: 2013 VQTVSQEHNTESSR-VTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQ 2071

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031
              EI++                    K     Q +         IP+   +L+  E+  +
Sbjct: 2072 RPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRR-EIAPR 2130

Query: 1032 DVAILEVEINSETADVVWER--DG---EIIKPKKNKYDFEKRGHIR--------KLYIRN 1078
                L  +I  + ADV  E   DG     IK +KN     +  H R         + ++ 
Sbjct: 2131 FTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQ 2190

Query: 1079 TSVHDEGEY----SCILRDESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT- 1131
              V D G Y    S  +   + TA++ V +   PP    RLQ Q   KG K T E+E+T 
Sbjct: 2191 VGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTG 2250

Query: 1132 KGDALVRWFKDGSEIQ---FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184
              +  V W KD   ++    S H +L   G   +L I      D+G+Y        G +K
Sbjct: 2251 LPEPTVTWLKDDKPLKDAGISEH-RLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAK 2309

Query: 1185 CTAILTVEEPS 1195
              A   + EPS
Sbjct: 2310 SIADCAILEPS 2320



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 147/637 (23%), Positives = 240/637 (37%), Gaps = 90/637 (14%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F++  K     EG   + EC +   PEP + W   G  I  + +     +  +   C 
Sbjct: 1377 PLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGI---CR 1433

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQG 749
             L I          ++  A N  G       L ++    E    PP+++  L+S    +G
Sbjct: 1434 -LVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEG 1492

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807
             S   +  V G P PT+ W KN+K +   P       +    LK ++V  +D+ VYT  A
Sbjct: 1493 SSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSA 1552

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  GI   SA + V EP E   E P F         +    IKL A V   P P + W 
Sbjct: 1553 SNPAGIEHCSASLIV-EPLEP-TELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 1610

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923
             N +   P ++    ++   + L+I       D+G Y   A N AG++     V +    
Sbjct: 1611 HNGKPFQPRDS---KYEYGRVTLIIPQAYPN-DAGSYVLSAKNLAGEAYTSCNVIVKGRL 1666

Query: 924  -----------DVEKVTFVKHLQ-KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969
                       D+E +    HL  K     EGK V L+C        +  WYHN++ +  
Sbjct: 1667 PNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKE 1726

Query: 970  MDHREIIQEGRXXXXXXXXXXXXDVGVIKCI------------------VKDQETST--- 1008
                +++ +G             D G  K +                  +   E +T   
Sbjct: 1727 SADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQ 1786

Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVW-ERDGEIIKPKKNKY 1063
                 + K++ P+F R L D    E +  +LEV+ +  +     W   + E+   ++   
Sbjct: 1787 AERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITT 1846

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV--VELPP---------E 1108
              +    + KL + N S  D+G Y+  +     D  C + + V  V  P          E
Sbjct: 1847 QSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVE 1906

Query: 1109 IITRLQNQKVNK--GNKATFEIELTKGDALVR--------WFKDGSEIQFSNHIQLTIDG 1158
            II R Q  +  +   +K     E+ K + +V+        WF +   +   N + ++  G
Sbjct: 1907 IIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFL-VSTSG 1965

Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191
            ++Q L I     D  G+ SC    E G + C A L +
Sbjct: 1966 ERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNI 2002



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 99/384 (25%), Positives = 156/384 (40%), Gaps = 43/384 (11%)

Query: 469  VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEK---PTSEEQSMAPIFVEKLRPK-HTP-- 522
            +P  Y  D  +Y    +    E      V  K   P     S     +E ++P  H P  
Sbjct: 1632 IPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLK 1691

Query: 523  -----DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
                 +G  V+ +C + G P P++ W+     +K S D Q+ +  D   +L+I+EV+ ED
Sbjct: 1692 DVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDR-CSLIIQEVYQED 1750

Query: 578  AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
            AG +  VA N+AG ASS+ EL V  PL+                      + +   P F 
Sbjct: 1751 AGHYKVVAINSAGEASSSCELKV-TPLNQ--------AEPATRAQAERQSLPKDSQPKFE 1801

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            +       DEG  ++LE +          W    +E+  D+ I+   +S++ ++  +L  
Sbjct: 1802 RLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLIL-- 1859

Query: 698  TNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGE-----KEPPQVIE-----PLKSM 744
             NV    +G YTV   N  G+A   S  IV  +   E     +   ++IE       K +
Sbjct: 1860 NNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKEL 1919

Query: 745  IV-RQGE--SVI-LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798
               +QGE   VI     V G P P + W  N++PV        + G+   +TI K     
Sbjct: 1920 FSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTH-D 1978

Query: 799  DEGVYTLKAENSEGIAETSAVITV 822
              G  +  AEN  G A   A + +
Sbjct: 1979 AVGKISCVAENEAGKATCVAFLNI 2002



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 51/205 (24%), Positives = 100/205 (48%), Gaps = 11/205 (5%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            I P F+     + VD+G+D+ +E      P P+I     G ++  D +  ++ + +    
Sbjct: 2127 IAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNR--- 2183

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               +++  V     G Y V A N  G+++    L +K     PP     L++ + ++GE 
Sbjct: 2184 -VTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKK-TIFPPVFGRRLQAQVSKKGEK 2241

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVYTLK 806
            + +  +V G P PT+TW K++KP+K          + G+++ + I++  +  D G Y ++
Sbjct: 2242 LTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL-IIEKAQTTDSGKYMVR 2300

Query: 807  AENSEGIAETSAVITVEEPTEENAE 831
            A N+ G A++ A   + EP+ E  +
Sbjct: 2301 ATNAGGEAKSIADCAILEPSPERLQ 2325



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 87/403 (21%), Positives = 157/403 (38%), Gaps = 30/403 (7%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P+P  EW  +   I+     K + D     L I++    D+  +  R  N  G  D    
Sbjct: 1404 PEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNAT 1463

Query: 1375 VTILDKPS-----PPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTE 1426
            +++ +  +     PP     L+   ++    +            T+ ++  +    D+ +
Sbjct: 1464 LSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPD 1523

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
            ++   N  +     + +       +   A N   I   S +    + ++ T++  P+ + 
Sbjct: 1524 YVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL-IVEPLEPTEL--PSFKV 1580

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXX 1545
            PL N      + I+L  I GG+P+P+V W  +GK  +   + YE  R             
Sbjct: 1581 PLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDA 1640

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQK-PVITISNE---DIKQ-KHKV-----------GDE 1589
              Y   A N  GE  TSC V ++ + P  T  +E   DI+  K  V           G  
Sbjct: 1641 GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKP 1700

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
              +  VI G P PEVIWY N   ++   +  +  +     + I+E+ +  +  Y + A N
Sbjct: 1701 VRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAIN 1760

Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
            +AG +S    LKV   P     P    +  R+S+  + +P  +
Sbjct: 1761 SAGEASSSCELKV--TPLNQAEPATRAQAERQSLPKDSQPKFE 1801



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 12/207 (5%)

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATY 1529
            +  E +  SP   +PLK+  +   +     C   G P+P V W++DG  ++T    K T+
Sbjct: 1368 IFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTF 1427

Query: 1530 ENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQ----- 1582
            +                  + C A N  G  +T+  + +++    + +    I +     
Sbjct: 1428 DKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSG 1487

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K   G  +    V+ G+P P V W+KN   +++  +Y I+     + ++ +E+     + 
Sbjct: 1488 KATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 1547

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            YT  ASN AG      +L V  +P +P
Sbjct: 1548 YTCSASNPAGIEHCSASLIV--EPLEP 1572



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 93/408 (22%), Positives = 171/408 (41%), Gaps = 39/408 (9%)

Query: 1001 VKDQETSTMLVVKETIPEF---IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
            +++Q T   L  ++   E    I+ L+D   +E++V +    I  E   +  E +  I +
Sbjct: 1263 IREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQN--IRDEETRIRREEEERIRR 1320

Query: 1058 PKKNKYDFEKRGHIRKLYI-RNTSVHDEGEYSCIL-----RDESCTAEVTVVELPPEIIT 1111
              +++   E+   I++  I R  ++ D+ +   I+     +D    +  T +     + T
Sbjct: 1321 ENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFT 1380

Query: 1112 R-LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
            R L++    +G++  FE E+T   +  V WFKDG  IQ ++  + T D    +L I +  
Sbjct: 1381 RPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETF 1440

Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTL---RLPEFILVPANTD------AYL 1216
              D+  +SC     VG     A L+V E +    L   R+  F+     T+      A +
Sbjct: 1441 AADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACV 1500

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS- 1275
               +P  T  V W+K    I+D+  + +  +  + TL   +   +D   YTC   +    
Sbjct: 1501 VAGVPLPT--VQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGI 1558

Query: 1276 ---TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
               +  L VE +E P ++  ++        + G  + L       P+P   W+ N K  +
Sbjct: 1559 EHCSASLIVEPLE-PTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQ 1617

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              + +K   +    +L I +    DAG Y L  +N  G A    NV +
Sbjct: 1618 P-RDSK--YEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIV 1662



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 107/435 (24%), Positives = 174/435 (40%), Gaps = 55/435 (12%)

Query: 996  VIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053
            V + I KD Q  S    ++   P F R L+D   +E D  + E E+       V W +DG
Sbjct: 1355 VTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDG 1414

Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-------- 1102
              I+   + K  F+K   I +L I  T   D   +SC   +   +C    T+        
Sbjct: 1415 ISIQTNSDYKTTFDKG--ICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAE 1472

Query: 1103 VEL-PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159
            V+L PP I+  LQ+ K  +G+   F   +  G  L  V+WFK+   I  S    ++ +  
Sbjct: 1473 VQLVPPRILRFLQSGKATEGSSFQFAC-VVAGVPLPTVQWFKNDKCIDDSPDYVISYNNG 1531

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVE--EPSINFTLRLPEFILVPANTD 1213
            +  LK  +  L+D   Y+C   N      C+A L VE  EP+      LP F +  +N  
Sbjct: 1532 EATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPT-----ELPSFKVPLSNAM 1586

Query: 1214 AYLTVEIPDETL-------DVTWYKKKSVIEDTE------KFTLI------SDVKKRTLI 1254
            A +  +I  E +       +V W       +  +      + TLI      +D     L 
Sbjct: 1587 ARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLS 1646

Query: 1255 IRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
             +    +       +    L +  S +++  ++    P +    ++  I  G  V L   
Sbjct: 1647 AKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCV 1706

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA- 1369
                P+P   W  N + +K+    +        SL I++V   DAG YK+   N+ G A 
Sbjct: 1707 IVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEAS 1766

Query: 1370 -DVEMNVTILDKPSP 1383
               E+ VT L++  P
Sbjct: 1767 SSCELKVTPLNQAEP 1781



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 1/93 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F+  L+      G T +FEC V+ +P+PQ+ W     +++      + Y  + V  L 
Sbjct: 3553 PLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHNGGLLESGSRHCIEY-RNGVCRLT 3611

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            + + +P+D G++ C A N  G A+++  L V +
Sbjct: 3612 LPQAYPDDNGSYACTAINPLGAATTSGNLTVSS 3644



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 83/398 (20%), Positives = 148/398 (37%), Gaps = 46/398 (11%)

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
            TE     PLF    ++   +E         VT  P P++ W+++   I  +      FD 
Sbjct: 1370 TELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDK 1429

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-----DVEKV--TFVKHLQKSY 938
                LVI    +  DS  + C ASN  G     A +++     +V+ V    ++ LQ   
Sbjct: 1430 GICRLVIEETFA-ADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGK 1488

Query: 939  ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
             T EG +    C  +     + +W+ N K I       I                 D  V
Sbjct: 1489 AT-EGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 1547

Query: 997  IKCIVKD----QETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047
              C   +    +  S  L+V+      +P F   L +   +      LE  +      +V
Sbjct: 1548 YTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEV 1607

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY-------------SC----- 1089
             W  +G+  +P+ +KY++   G +  L I     +D G Y             SC     
Sbjct: 1608 YWLHNGKPFQPRDSKYEY---GRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVK 1663

Query: 1090 -ILRDESCTAEVT--VVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSE 1145
              L +E+  +E+   +  + P +   L++  + +G     + + + + +  V W+ +   
Sbjct: 1664 GRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERP 1723

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ++ S  +QL   G +  L I +   +DAG Y     NS
Sbjct: 1724 VKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINS 1761



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            GD ++    + G P P V W+K+G  ++ + +Y  T  +    + I+E   + S++++  
Sbjct: 1391 GDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCR 1450

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE--GPVIMREISRESVT 1684
            ASN  GT     TL V +  ++ +   P I+R +     T
Sbjct: 1451 ASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKAT 1490



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 7/179 (3%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
            +P    PL     +   D+ +  I+ G P P++   ++G +L     T  +   NR    
Sbjct: 2128 APRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIE 2187

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAV 1595
                       Y   A N  G+  ++  + +++     +    ++ Q  K G++  +   
Sbjct: 2188 LKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVE 2247

Query: 1596 IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            + G+P P V W K+   L++    E+ +  +  +  + I++ + + S KY + A+N  G
Sbjct: 2248 VTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGG 2306



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            ST  L V+   FPP      +    K+G  +T+ V+    P+P   W+ + K +K    +
Sbjct: 2212 STADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGIS 2271

Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            +  +     S  L I+K + TD+G Y +R  N  G A    +  IL+ PSP
Sbjct: 2272 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILE-PSP 2321



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 3/103 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G +  + A+ +G P PE+   KNG +L  D    I+ K     I +K++    + +Y + 
Sbjct: 2143 GADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVT 2202

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIE 1686
            ASNT G S+    L V      P  G  +  ++S+  E +T+E
Sbjct: 2203 ASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME 2245



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            + PT   + +AP F   L  K    G+ V  E   +G+P P+I   +    +      ++
Sbjct: 2118 DSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRI 2177

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
              +  N  T+ +++V   DAG +   A N  G ++ST +L+V+
Sbjct: 2178 -SNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVK 2219



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 1/103 (0%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATL 568
            P+F  +L+ + +  G  +  E +V G P P +TW +    +K +           N   L
Sbjct: 2225 PVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL 2284

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
            +I +    D+G +   A NA G A S  +  +  P  +   E+
Sbjct: 2285 IIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEV 2327



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            PLFI   ++I V   GT +    V  +P P + W  N  ++         +      L +
Sbjct: 3553 PLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHNGGLLESGSRHCIEYRNGVCRLTL 3612

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
                 + D+G Y C A N  G ++    +T+
Sbjct: 3613 PQAYPD-DNGSYACTAINPLGAATTSGNLTV 3642



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 36/169 (21%), Positives = 60/169 (35%), Gaps = 11/169 (6%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------LDAKSTTKLK 1280
            V W+K    I+    +    D     L+I +    D   ++C         D  +T  ++
Sbjct: 1408 VEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVR 1467

Query: 1281 ---VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
                EV   PP+I+ + +  +   GS           P P  +W  N K I        S
Sbjct: 1468 ENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVIS 1527

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPP 1384
             ++  A+L  ++V   D  +Y     N  G  H    + V  L+    P
Sbjct: 1528 YNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELP 1576



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/86 (24%), Positives = 39/86 (45%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + +G+DV++   Y  FP P  +   N   + +  HT+ S      ++ +K+V   DAG Y
Sbjct: 2140 VDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRY 2199

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384
             +   N  G +    ++ +     PP
Sbjct: 2200 AVTASNTVGQSTSTADLVVKKTIFPP 2225


>UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome
            shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
            SCAF14556, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2646

 Score =  152 bits (368), Expect = 1e-34
 Identities = 185/765 (24%), Positives = 307/765 (40%), Gaps = 63/765 (8%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAIES 686
            ++   P  F+K+ ++Q VDEG D+ L C L + P   + W  KGE  + P     +    
Sbjct: 37   VVNAAPVLFTKELESQTVDEGDDVRLHCEL-SKPAVPLEWK-KGELGLCPCTKYDIKQAG 94

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-------VLKIKTGEKEPPQVIE 739
                  + L I +V     G+YT    + +  A L +       +L I +   +P     
Sbjct: 95   TR----ATLVIHDVDPEDSGSYTCDTGDCQSTAQLIVKVPFRNTILLIFSHAAQPVLFKT 150

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKK 796
             L+++  + GES  L  +    P  ++ W   +K + +      + DG T  + + K + 
Sbjct: 151  QLQNLERQAGESASLCCETT-KPGASVVWRHGDKVLSSSSKYRLRQDGSTVELVVYKLQG 209

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVAR 855
              D GVY+       G   TSAV+TV+E         + I +F E  V  +G  ++    
Sbjct: 210  -PDAGVYSCDT----GSQRTSAVLTVQEIE-------VSILKFLESCVVSEGEDVRFECL 257

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            V+R   P + W   +  +  ++      DG    L +  V +E DSG      + + G  
Sbjct: 258  VSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGV-TEADSG----TVTFTVGNH 312

Query: 916  SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHRE 974
            +  A +T+    V F K L+   E  EG   IL C+TSH   S +W      ++  D   
Sbjct: 313  TSTASLTVKAAPVLFKKELENQ-EVLEGDKAILSCETSHPDCSVRWLKGSTVLTHGDKYS 371

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034
            I Q               D G   C   D+ +S  L V+E +   +R+L D  V     A
Sbjct: 372  IEQRATAHTLCIHKLDVKDSGEYTCDTGDKRSSASLTVREHV-RILRELCDVTVTTGQDA 430

Query: 1035 ILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
            + EVE++    TA   W  D  +     N+   E  G + +L ++  +  + G+ + ++ 
Sbjct: 431  LFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSE--GRVHRLALKMVTTDESGDVAFVVG 488

Query: 1093 DESCTAEVTVVELP---PEIITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
            D+   A + V E P   P    + L+NQ   +G+  +   EL+K    V W K G  IQ 
Sbjct: 489  DQKSVACLLVEEKPKGAPVFFRKELKNQDAVEGDDVSLRCELSKPGIRVEWRKGGMVIQP 548

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE---F 1205
            S   ++   G  Q+L I +   +D+G Y+C+ G+   TA L V+   +     L     F
Sbjct: 549  SKKYEMKQKGCVQELCIQNLVSEDSGYYTCDAGDQLTTAALAVQAKEVLIVCGLKTTDVF 608

Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQ 1263
            +   A     L+   P +   V W+   + +E +  FT I  S     TL ++    DD 
Sbjct: 609  VGEWATFSCQLSARAPGK---VQWWLDGTRLE-SSAFTEIGLSQGHIYTLTLKNLAPDDS 664

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
                 V+  A S T     +V+ P  ++V    +  +        +  Y         W 
Sbjct: 665  ---GTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVVENQPAEFICQYSR--PVKARWR 719

Query: 1323 VNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
             N + ++   +      D   A L I +V   D G Y    E  C
Sbjct: 720  KNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYACEAEGTC 764



 Score =  128 bits (309), Expect = 2e-27
 Identities = 90/338 (26%), Positives = 151/338 (44%), Gaps = 27/338 (7%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+F+ +L+ +  PDG  V F+C V G P P + W++   +++ +  + +  D +    L
Sbjct: 1351 APVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQL 1410

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS---DHGSEMTVXXXXXXXXXXXX 625
            +I  V P D G + C A+N +G  S+  EL V+   S   D  ++ T             
Sbjct: 1411 IITTVLPTDMGVYRCTAENGSGITSTKAELRVDMSCSSDYDTAADATETSSYVSAKGYIS 1470

Query: 626  AD--ILEGIP-----PTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDIAWLFKGEEIVPD 677
             D    E +      P   ++    +V  G+ I  ++ ++   P+P + W   G  +   
Sbjct: 1471 RDTETFESVTEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSS 1530

Query: 678  ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PP 735
            E I + +E D+H     L+I  VK+   G Y+    N  G A     L +   ++   PP
Sbjct: 1531 ERILLQVERDVHS----LEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPP 1586

Query: 736  QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN--------KP-VKALPTKSDGDT 786
            + +E   +  V+QG S+ LS +V G+P P ++W K          KP  K     S G  
Sbjct: 1587 RFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHR 1646

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            HS+ IL     +  G YT  A N  G +  +A + V++
Sbjct: 1647 HSL-ILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDD 1683



 Score =  122 bits (293), Expect = 1e-25
 Identities = 155/693 (22%), Positives = 271/693 (39%), Gaps = 56/693 (8%)

Query: 993  DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052
            D G   C   D  +S  LVV      F ++L+   V E D   L  E++     + W++ 
Sbjct: 19   DSGSYSCCSDDTISSASLVVNAAPVLFTKELESQTVDEGDDVRLHCELSKPAVPLEWKK- 77

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP------ 1106
            GE+      KYD ++ G    L I +    D G Y+C   D   TA++ +V++P      
Sbjct: 78   GELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTAQL-IVKVPFRNTIL 136

Query: 1107 --------PEII-TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157
                    P +  T+LQN +   G  A+   E TK  A V W      +  S+  +L  D
Sbjct: 137  LIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDKVLSSSSKYRLRQD 196

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
            G   +L +Y     DAG YSC+ G+ + +A+LTV+E  ++  L+  E  +V    D    
Sbjct: 197  GSTVELVVYKLQGPDAGVYSCDTGSQRTSAVLTVQEIEVSI-LKFLESCVVSEGEDVRFE 255

Query: 1218 VEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
              +  E   +  +K + V ++D +   + SD +  +L +R  TE D    T  + +  ST
Sbjct: 256  CLVSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGVTEADSGTVTFTVGNHTST 315

Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
              L V+     P +   E E +     D  +L    + P  +  W+  S ++      K 
Sbjct: 316  ASLTVKAA---PVLFKKELENQEVLEGDKAILSCETSHPDCSVRWLKGSTVL--THGDKY 370

Query: 1337 SIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
            SI+ ++   +L I K++  D+G Y       C   D   + ++  +        IL    
Sbjct: 371  SIEQRATAHTLCIHKLDVKDSGEY------TCDTGDKRSSASLTVRE----HVRILR--- 417

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
                +C D    TG   +    + +  +   EW    N+ +     Q       +R    
Sbjct: 418  ---ELC-DVTVTTGQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSEGRVHRLALK 473

Query: 1455 AVNEVDISDASETTEYYK-----VIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGV 1508
             V   +  D +      K     +++E    +P    K LKN      +D+ L C     
Sbjct: 474  MVTTDESGDVAFVVGDQKSVACLLVEEKPKGAPVFFRKELKNQDAVEGDDVSLRCEL-SK 532

Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSCVVGI 1567
            P  +V W + G  ++ +K  YE +                    +  D G+  T+  + +
Sbjct: 533  PGIRVEWRKGGMVIQPSK-KYEMKQKGCVQELCIQNLVSEDSGYYTCDAGDQLTTAALAV 591

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLV-TAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKE 1625
            Q K V+ +    +K       EW   +  +    P +V W+ +G +LE+     I  ++ 
Sbjct: 592  QAKEVLIVCG--LKTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQG 649

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
                + +K L    S     +A +   T+ + V
Sbjct: 650  HIYTLTLKNLAPDDSGTVMFKAGSLTSTAKLLV 682



 Score =  120 bits (290), Expect = 3e-25
 Identities = 188/919 (20%), Positives = 356/919 (38%), Gaps = 73/919 (7%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V EG D+  EC +     P + W  K +++   +N    IESD  ++   L+   V +  
Sbjct: 246  VSEGEDVRFECLVSREEAPLVQW--KLQDVPLQDNQMNVIESDGRLHSLTLR--GVTEAD 301

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             GT T    N    ASL +       +KE       L++  V +G+  ILS +   +P  
Sbjct: 302  SGTVTFTVGNHTSTASLTVKAAPVLFKKE-------LENQEVLEGDKAILSCET-SHPDC 353

Query: 765  TITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            ++ W K +  +        +     H++ I K   VKD G YT       G   +SA +T
Sbjct: 354  SVRWLKGSTVLTHGDKYSIEQRATAHTLCIHK-LDVKDSGEYTCDT----GDKRSSASLT 408

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            V E           +    ++TV           ++ + V +  W+  + ++  ++    
Sbjct: 409  VREHVR-------ILRELCDVTVTTGQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQM 461

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
            + +G    L +  V ++ +SGD   V  +    +            V F K L K+ +  
Sbjct: 462  SSEGRVHRLALKMVTTD-ESGDVAFVVGDQKSVACLLVEEKPKGAPVFFRKEL-KNQDAV 519

Query: 942  EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            EG  V L C+ S   +  +W      I      E+ Q+G             D G   C 
Sbjct: 520  EGDDVSLRCELSKPGIRVEWRKGGMVIQPSKKYEMKQKGCVQELCIQNLVSEDSGYYTCD 579

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPK 1059
              DQ T+  L V+      +  L+  +V   + A    ++++     V W  DG  ++  
Sbjct: 580  AGDQLTTAALAVQAKEVLIVCGLKTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESS 639

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
                    +GHI  L ++N +  D G         + TA++ V +   E+++ +++  V 
Sbjct: 640  AFTEIGLSQGHIYTLTLKNLAPDDSGTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVV 699

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            +   A F  + ++     RW K+G  ++     + +  D    +L I     +D G Y+C
Sbjct: 700  ENQPAEFICQYSR-PVKARWRKNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYAC 758

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
            E   +   A L VE   I     L    +       +       E+ D  W      +++
Sbjct: 759  EAEGTCVVASLHVEAKPITIVQGLENVEIFNGGEALFECALSRPESKDCRWLLDGKPVKE 818

Query: 1239 TEKFTLIS--DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKI-VD 1292
            +    ++S  + ++  L++++ +  D C  T     A ++ +L V+V    E+ P   ++
Sbjct: 819  SPTTEIVSFENGRRHLLLMKELSVKDTCTVTFKAGTASTSAQLSVKVATGSEWQPSTQLE 878

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQP------------NDEWIVNSKIIKKCKHTKPSIDS 1340
                  + +   +  +V  +   QP            +D W  ++K  K+    +P++DS
Sbjct: 879  AVEPVELPQTVQLEKVVKPEELGQPSLPPEAAEEGDLHDLWEASAK--KRRMSREPTLDS 936

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN-----ILEIDSS 1395
                  I +    D G+ K   +   GH  VE+     D+     K +       E +SS
Sbjct: 937  ------ISEQPEEDKGVRKPVDKELQGHETVEVKSVKKDEVIKSKKVDSKLYTSSEEESS 990

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAY 1454
            S  +         +++ +    + + + T  +     + + +T  +  ++T +  +    
Sbjct: 991  SGGLSLVAYLKKSSTSAVTATNDAETLSTERFFEHFQMAEHRTVQVTKVETTTDQQTPEK 1050

Query: 1455 AV------NEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
             V       E ++S+A+ +    +K  K  K   P  ++  K+ T EP+  I L C+  G
Sbjct: 1051 LVPVEKKSEEEELSEAAVKIQAAFKGYKARKDMRPVFKETFKDQTKEPSGTIHLECVVQG 1110

Query: 1508 VPQPKVTWYRDGKKLKTAK 1526
             P  KV W +DG+ L   K
Sbjct: 1111 KPD-KVRWLKDGELLTDGK 1128



 Score =  109 bits (263), Expect = 6e-22
 Identities = 121/573 (21%), Positives = 229/573 (39%), Gaps = 37/573 (6%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++  P  F K+ + Q V EG   +L C   + P+  + WL     +   +  S+   +  
Sbjct: 320  VKAAPVLFKKELENQEVLEGDKAILSCE-TSHPDCSVRWLKGSTVLTHGDKYSIEQRATA 378

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            H  C + K+ +VK    G YT    ++   ASL +        +E  +++  L  + V  
Sbjct: 379  HTLC-IHKL-DVK--DSGEYTCDTGDKRSSASLTV--------REHVRILRELCDVTVTT 426

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            G+  +   ++  +      W   +  ++        S+G  H +  LK     + G    
Sbjct: 427  GQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSEGRVHRLA-LKMVTTDESGDVAF 485

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
               + + +A     + VEE  +    P  F    +     E   + L   +++ P   + 
Sbjct: 486  VVGDQKSVA----CLLVEE--KPKGAPVFFRKELKNQDAVEGDDVSLRCELSK-PGIRVE 538

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W +   +I PS+       G   EL I N+ SE DSG Y C     AG     A + +  
Sbjct: 539  WRKGGMVIQPSKKYEMKQKGCVQELCIQNLVSE-DSGYYTC----DAGDQLTTAALAVQA 593

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREI-IQEGRXX 982
            ++V  V  L K+ +   G+     CQ S     K  W+ +   +      EI + +G   
Sbjct: 594  KEVLIVCGL-KTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQGHIY 652

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042
                      D G +        ++  L+VK+   E + +++D  V E   A    +  S
Sbjct: 653  TLTLKNLAPDDSGTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVVENQPAEFICQY-S 711

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
                  W ++G+ ++    +   E+  ++ +LYI   S  D G Y+C        A + V
Sbjct: 712  RPVKARWRKNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYACEAEGTCVVASLHV 771

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DGK 1159
               P  I+  L+N ++  G +A FE  L++ ++   RW  DG  ++ S   ++    +G+
Sbjct: 772  EAKPITIVQGLENVEIFNGGEALFECALSRPESKDCRWLLDGKPVKESPTTEIVSFENGR 831

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            +  L + +  + D    + + G +  +A L+V+
Sbjct: 832  RHLLLMKELSVKDTCTVTFKAGTASTSAQLSVK 864



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 59/206 (28%), Positives = 107/206 (51%), Gaps = 13/206 (6%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG 784
            T + + PQ++E L  + V  G  +  +  +V G P+P + W K+  P+++   +  + + 
Sbjct: 1480 TEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERILLQVER 1539

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
            D HS+ I++ K+  D G Y+    N+ G A +SA +TV   ++E   PP F+ RF    V
Sbjct: 1540 DVHSLEIVEVKR-SDMGEYSAYISNAAGSAYSSARLTVLN-SKEPLVPPRFLERFSNRKV 1597

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEI-----ISP-SETITQNFDGENIELVITNVDSE 898
            K+  +I L  +V  +P P ++W +   +     I P ++       G    L++ +V +E
Sbjct: 1598 KQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHRHSLILMDVGTE 1657

Query: 899  IDSGDYKCVASNSAGKSSHGARVTID 924
              +G Y C+A+N AG+S   A + +D
Sbjct: 1658 Y-TGAYTCIATNRAGQSICTAHLEVD 1682



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 75/346 (21%), Positives = 130/346 (37%), Gaps = 15/346 (4%)

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132
            +L I      D G YSC   D   +A + V   P      L++Q V++G+      EL+K
Sbjct: 9    ELVIMELRPEDSGSYSCCSDDTISSASLVVNAAPVLFTKELESQTVDEGDDVRLHCELSK 68

Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
                + W K    +       +   G +  L I+D D +D+G Y+C+ G+ + TA L V+
Sbjct: 69   PAVPLEWKKGELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTAQLIVK 128

Query: 1193 EPSINFTLRLPEFILVP-------------ANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239
             P  N  L +      P             A   A L  E       V W     V+  +
Sbjct: 129  VPFRNTILLIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDKVLSSS 188

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299
             K+ L  D     L++ K    D   Y+C     +++  L V+ +E    I+ +     +
Sbjct: 189  SKYRLRQDGSTVELVVYKLQGPDAGVYSCDTGSQRTSAVLTVQEIEV--SILKFLESCVV 246

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
              G DV           P  +W +    ++  +      D +  SLT++ V   D+G   
Sbjct: 247  SEGEDVRFECLVSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGVTEADSGTVT 306

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
              + N+   A + +    +          +LE D + ++     P+
Sbjct: 307  FTVGNHTSTASLTVKAAPVLFKKELENQEVLEGDKAILSCETSHPD 352



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 59/227 (25%), Positives = 103/227 (45%), Gaps = 34/227 (14%)

Query: 498  FEKPTSEEQSMAPIFVEKLRPKHTPDGSTV-QFECQVEGYPRPQITWFRQTAIIKPSQDF 556
            FE  T ++Q   P  VE+L   H   G+ + + + +V+G+P+P++ WF+    ++ S+  
Sbjct: 1476 FESVTEDDQ--LPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERI 1533

Query: 557  QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXX 616
             +  + D V +L I EV   D G ++    NAAG A S+  L V      +  E  V   
Sbjct: 1534 LLQVERD-VHSLEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVL-----NSKEPLV--- 1584

Query: 617  XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG--EEI 674
                            PP F ++   + V +G+ I L  ++   P P ++WL +   E++
Sbjct: 1585 ----------------PPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDV 1628

Query: 675  --VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
              +  +     I S  H +  +L   +V     G YT +A NR G++
Sbjct: 1629 LWIKPDTKGYKIASSGHRHSLIL--MDVGTEYTGAYTCIATNRAGQS 1673



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 19/228 (8%)

Query: 1090 ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147
            I RD      VT  +  P+I+  L +  V+ G   T      KG     V WFKDG  ++
Sbjct: 1469 ISRDTETFESVTEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLR 1528

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEF 1205
             S  I L ++     L+I +    D GEYS  + N+  +A  +     +N    L  P F
Sbjct: 1529 SSERILLQVERDVHSLEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPPRF 1588

Query: 1206 I------LVPANTDAYLTVEIP-DETLDVTWYKKKSVIE------DTEKFTLISDVKKRT 1252
            +       V   T   L+V++    T  V+W K++S+ +      DT+ + + S   + +
Sbjct: 1589 LERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHRHS 1648

Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYR 1298
            LI+     +    YTC+  +   +S     +EV + P +    +++ R
Sbjct: 1649 LILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDDIPQRRRQQKKKVR 1696



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 1/116 (0%)

Query: 485  QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
            +++L+E   K+    K     + M P+F E  + +      T+  EC V+G P  ++ W 
Sbjct: 1060 EEELSEAAVKIQAAFKGYKARKDMRPVFKETFKDQTKEPSGTIHLECVVQGKP-DKVRWL 1118

Query: 545  RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +   ++   + + +   +D   +LVI  +  +D G +TC   N  G +S + ++ V
Sbjct: 1119 KDGELLTDGKHYHIDIYNDGTCSLVITAITTKDTGVYTCEVTNKFGVSSHSGKVTV 1174



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 5/104 (4%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-----IKPSQDFQ 557
            S+E  + P F+E+   +    G+++    +VEG P P ++W ++ ++     IKP     
Sbjct: 1579 SKEPLVPPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGY 1638

Query: 558  MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
                  +  +L++ +V  E  G +TC+A N AG +  T  L V+
Sbjct: 1639 KIASSGHRHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVD 1682



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 12/212 (5%)

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
            G   +L I +   +D+G YSC   ++  +A L V    + FT  L E   V    D  L 
Sbjct: 5    GLHYELVIMELRPEDSGSYSCCSDDTISSASLVVNAAPVLFTKEL-ESQTVDEGDDVRLH 63

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             E+    + + W K +  +    K+ +     + TL+I     +D   YTC   D +ST 
Sbjct: 64   CELSKPAVPLEWKKGELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTA 123

Query: 1278 KLKVEVV-----------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            +L V+V               P +   + +   ++  +   L      P  +  W    K
Sbjct: 124  QLIVKVPFRNTILLIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDK 183

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++      +   D  +  L + K++  DAG+Y
Sbjct: 184  VLSSSSKYRLRQDGSTVELVVYKLQGPDAGVY 215



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 24/96 (25%), Positives = 45/96 (46%)

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
            A  P+F+   Q   V +   +     V   P P++ WY++ +++  ++    N D E  +
Sbjct: 1349 AAAPVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQ 1408

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
             +I       D G Y+C A N +G +S  A + +D+
Sbjct: 1409 QLIITTVLPTDMGVYRCTAENGSGITSTKAELRVDM 1444



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 23/88 (26%), Positives = 40/88 (45%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            ++G P P V W+K+G+ L + +   +  +     + I E+KRS   +Y+   SN AG++ 
Sbjct: 1510 VKGFPKPRVYWFKDGHPLRSSERILLQVERDVHSLEIVEVKRSDMGEYSAYISNAAGSAY 1569

Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESV 1683
                L V +       P  +   S   V
Sbjct: 1570 SSARLTVLNSKEPLVPPRFLERFSNRKV 1597



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-FDGENIELV 891
            P+F   F++ T +  GTI L   V   P   + W ++ E+++  +    + ++     LV
Sbjct: 1085 PVFKETFKDQTKEPSGTIHLECVVQGKP-DKVRWLKDGELLTDGKHYHIDIYNDGTCSLV 1143

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            IT + ++ D+G Y C  +N  G SSH  +VT+
Sbjct: 1144 ITAITTK-DTGVYTCEVTNKFGVSSHSGKVTV 1174



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 1/105 (0%)

Query: 1288 PKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            P+IV+   +  +  G+ +T + +  + FP+P   W  +   ++  +     ++    SL 
Sbjct: 1486 PQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERILLQVERDVHSLE 1545

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
            I +V+ +D G Y   + N  G A     +T+L+   P   P  LE
Sbjct: 1546 IVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPPRFLE 1590



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 7/96 (7%)

Query: 509 API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
           AP+ F ++L  +   +G  V+  C++   P   + W +    + P   + +       AT
Sbjct: 41  APVLFTKELESQTVDEGDDVRLHCELSK-PAVPLEWKKGELGLCPCTKYDIKQAGTR-AT 98

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           LVI +V PED+G++TC      G   ST +LIV+ P
Sbjct: 99  LVIHDVDPEDSGSYTC----DTGDCQSTAQLIVKVP 130



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 1107 PEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGK-KQKLK 1164
            P  +T LQ+Q V  G   +F+ + + K    VRW+KDG  ++ ++H  +  D + +Q+L 
Sbjct: 1352 PVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQLI 1411

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            I      D G Y C   N
Sbjct: 1412 ITTVLPTDMGVYRCTAEN 1429



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 7/100 (7%)

Query: 504 EEQSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           E+   AP+F  K L+ +   +G  V   C++   P  ++ W +   +I+PS+ ++M    
Sbjct: 500 EKPKGAPVFFRKELKNQDAVEGDDVSLRCELSK-PGIRVEWRKGGMVIQPSKKYEMK-QK 557

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
             V  L I+ +  ED+G +TC     AG   +T  L V+A
Sbjct: 558 GCVQELCIQNLVSEDSGYYTC----DAGDQLTTAALAVQA 593



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 3/84 (3%)

Query: 1582 QKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRS 1638
            Q   V D + V+   V+ G PPP V WYK+G  LE +  Y I   +E    + I  +  +
Sbjct: 1359 QSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQLIITTVLPT 1418

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV 1662
                Y   A N +G +S +  L+V
Sbjct: 1419 DMGVYRCTAENGSGITSTKAELRV 1442



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 14/123 (11%)

Query: 1008 TMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEI-----IKPK 1059
            T+L  KE +  P F+ +  + +VK+     L V++  S T  V W ++  +     IKP 
Sbjct: 1575 TVLNSKEPLVPPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPD 1634

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQN 1115
               Y     GH   L + +      G Y+CI  + +    CTA + V ++P     R Q 
Sbjct: 1635 TKGYKIASSGHRHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDDIPQR--RRQQK 1692

Query: 1116 QKV 1118
            +KV
Sbjct: 1693 KKV 1695



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 541  ITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599
            + WF+ + ++   + +Q Y +    V  LVI+ +   D G + C   N  G A    +L+
Sbjct: 2201 VEWFKDSRLLTDQEKYQTYSELRSGVLVLVIKNLTERDLGHYECEMSNRLGSARCGADLV 2260

Query: 600  VEAPLSDHGSE-MTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
            + + ++  G + +T+              I+E    T  K P+
Sbjct: 2261 LPSAVARTGEQAVTIEVTEQETKIPKKTIIIEETITTVVKNPR 2303



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G  V+FEC V     P + W  Q   ++ +Q   +   D  + +L +R V   D+GT T
Sbjct: 248 EGEDVRFECLVSREEAPLVQWKLQDVPLQDNQ-MNVIESDGRLHSLTLRGVTEADSGTVT 306

Query: 583 CVAKNAAGFASSTTE 597
               N    AS T +
Sbjct: 307 FTVGNHTSTASLTVK 321



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G    F CQ+      ++ W+     ++ S   ++     ++ TL ++ + P+D+GT   
Sbjct: 610 GEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQGHIYTLTLKNLAPDDSGT--- 666

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEM 611
                AG  +ST +L+V+ P  +  SEM
Sbjct: 667 -VMFKAGSLTSTAKLLVKDPTVEVVSEM 693



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%)

Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           V ++   H  +    +F CQ   Y RP +  W +    ++      +   D NVA L I 
Sbjct: 690 VSEMEDIHVVENQPAEFICQ---YSRPVKARWRKNGQPLRADGRRVVVEQDWNVARLYIS 746

Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTE 597
            V  ED GT+ C A+     AS   E
Sbjct: 747 RVSTEDGGTYACEAEGTCVVASLHVE 772


>UniRef50_Q676A1 Cluster: Cardiac myosin-binding protein C; n=1;
            Oikopleura dioica|Rep: Cardiac myosin-binding protein C -
            Oikopleura dioica (Tunicate)
          Length = 1200

 Score =  151 bits (367), Expect = 2e-34
 Identities = 117/501 (23%), Positives = 218/501 (43%), Gaps = 37/501 (7%)

Query: 1022 KLQDFE-VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
            KL D E V      + E  + +E     W R+G+ I  +   +  E+RG  RKL I N +
Sbjct: 279  KLPDTECVPNNGKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENAN 338

Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWF 1140
            + D+G +     +E  + EV V+E P  +    ++ ++ +G  A F   L+      +  
Sbjct: 339  LMDDGLFEIRAGEEKSSCEVHVLEAPTAVTKGFEDLQLVQGEDAKFTATLSTAHGRFKIL 398

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200
            KDG E   +++  +T DG     +I      DAG Y  +   +K    L V+   + F  
Sbjct: 399  KDGIEFGLNDNQTVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKS 458

Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
            R  + + V  N  A  +  + D  +   W      +E++E   +I+D   R L++++  +
Sbjct: 459  RFSD-VNVNVNEPAEFSCIVSDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGK 517

Query: 1261 DDQCEYTCVL--LDAKSTTKLKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQ 1316
             ++ EY  ++   D K  T +   +  +   I     E+E  +K G   TL +     P 
Sbjct: 518  ANEGEYQFLVDSKDHKQPTGITATLKTYSVTIEKPQGEKEIVVKAGQKFTLDIPISGDPA 577

Query: 1317 PNDEWIVNSKIIKKCKHT--------------KP---SIDSKS----------ASLTIKK 1349
            P   W +  K +  C++T              KP     D K           + + I  
Sbjct: 578  PQMSWFLGEKEL-YCENTPSGEFTNPLDRPFDKPFGKPADPKQRVQIKNWPERSRVHIPT 636

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
            V   D+G+Y L+L++  G   ++  + ++ KP  PG P I E+++    + W  P   G 
Sbjct: 637  VHKADSGVYTLKLKSEAGTDSIDFKLLVIHKPGAPGIPIISELNNECCRVDWTPPVELGG 696

Query: 1410 STIIYYVVEYQEIDTTEWISVKN-ITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASET 1467
              +  Y+VE ++  ++ WI + + +T     + + +   ++Y+ R  AVN+V + + S  
Sbjct: 697  CEVEGYIVERKKTSSSRWIRLNSQLTTFHNHLARRMVEGTAYQVRVTAVNQVGVGEPSPV 756

Query: 1468 TEYYKVIKETKIQSPTVEKPL 1488
            +E +  +  T  + P++ K L
Sbjct: 757  SESFTPMAPTS-EIPSIRKGL 776



 Score =  101 bits (242), Expect = 2e-19
 Identities = 105/482 (21%), Positives = 193/482 (40%), Gaps = 37/482 (7%)

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            G   +  +   I    + S + I  + ++ S  YT++  + AGT S++  L V  KP  P
Sbjct: 612  GKPADPKQRVQIKNWPERSRVHIPTVHKADSGVYTLKLKSEAGTDSIDFKLLVIHKPGAP 671

Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
              P+I  E++ E   ++W PP++ GG E+  Y +E+ +  ++RWI++         +  +
Sbjct: 672  GIPIIS-ELNNECCRVDWTPPVELGGCEVEGYIVERKKTSSSRWIRLNSQLTTFHNHLAR 730

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789
            ++ E   Y  RV A N VG     E  P+        P+            ++S+ + W 
Sbjct: 731  RMVEGTAYQVRVTAVNQVGVG---EPSPVSESFTPMAPTSEIPSIRKGLTADDSIELKWA 787

Query: 1790 PSEKNGGSPIIDYKVEIK----------------QEGKKWKXXXXXXXXXARI-QKLSIN 1832
              E  G   +  Y ++++                   + WK         ++I   L   
Sbjct: 788  APEDQGALGMKGYLIQLQVLKNPSSENPLMELEDDAWEDWKKTKIAPDSNSQILDGLDTG 847

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEPE 1890
             TY FR+ A N  G S  +T+   +   + +  P  + PR             L +  P 
Sbjct: 848  KTYMFRMAAENAAGRS-KWTTFGPVVCAEAMEDPRINLPRPLTRLVKIRCGEKLHFQCPF 906

Query: 1891 SNGGSPITNYI-IEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVG- 1947
                 P+  +  ++    +G +          + EH  +        I  R +  +  G 
Sbjct: 907  VGRPKPVVTWTKVDSLPEEGVNTLPEGVEEKPLGEHVTVRESVGMAVIHIRNTDRSDTGC 966

Query: 1948 --VSLPT-ESQSVRLEKHATV--PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
              + L   + ++V + K A V  PS P A   +  +G++ V   W +P+ DG   +  Y 
Sbjct: 967  YKMRLAVGDKEAVAIIKVAIVEPPSKPRALKIVETIGTS-VQLEWESPKDDGNTEIFAYT 1025

Query: 2003 IAIRDV---TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
            +  RD        W  V +  +   K +I DL   + +  R+ A+NE+GLSE + + +  
Sbjct: 1026 VEKRDKRSGADGQWFIVYE-KIRHCKCSIDDLIMGNEFQFRVKAQNEVGLSEGIATKDFA 1084

Query: 2060 KV 2061
            K+
Sbjct: 1085 KI 1086



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 65/247 (26%), Positives = 112/247 (45%), Gaps = 20/247 (8%)

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
            A + I+  + +D G YK+RL      A   + V I++ PS P    I+E   +S+ + W+
Sbjct: 952  AVIHIRNTDRSDTGCYKMRLAVGDKEAVAIIKVAIVEPPSKPRALKIVETIGTSVQLEWE 1011

Query: 1403 EPENTGNSTIIYYVVEYQE----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             P++ GN+ I  Y VE ++     D   +I  + I   + SI +L   + ++FR  A NE
Sbjct: 1012 SPKDDGNTEIFAYTVEKRDKRSGADGQWFIVYEKIRHCKCSIDDLIMGNEFQFRVKAQNE 1071

Query: 1459 VDISDASETTEYYKVIKE--TKI----------QSPTVEKPLKNITTEPNEDIELTCIFG 1506
            V +S+   T ++ K+ KE  T +          Q P+   PL N          ++C   
Sbjct: 1072 VGLSEGIATKDFAKIEKERLTYVKPEYKSRDVSQPPSFTLPLNNRKLTIGYTGTISCSVR 1131

Query: 1507 GVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            G P+PK+ W+++  ++    K   +                    Y C+A+NDHGEV   
Sbjct: 1132 GQPKPKIRWFKNKIEIIDNPKYKMSASLGVVQLEIRRPRQADQGTYTCLAYNDHGEVSCD 1191

Query: 1563 CVVGIQQ 1569
              V +++
Sbjct: 1192 AQVMVRE 1198



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 65/306 (21%), Positives = 123/306 (40%), Gaps = 10/306 (3%)

Query: 943  GKTVILECQTSHTVSTKWYHNKKEISGMD-HREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            GK V      +  + TKW+ N +EI+  + H +I Q GR            D G+ +   
Sbjct: 290  GKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENANLMDDGLFEIRA 349

Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061
             ++++S  + V E      +  +D ++ + + A     +++        +DG       N
Sbjct: 350  GEEKSSCEVHVLEAPTAVTKGFEDLQLVQGEDAKFTATLSTAHGRFKILKDGIEFGLNDN 409

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
            +    + G +    I+  S  D G Y           E+ V   P    +R  +  VN  
Sbjct: 410  Q-TVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKSRFSDVNVNVN 468

Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              A F   ++  +   +W  +G  ++ S +IQ+  DG  +KL + +    + GEY   V 
Sbjct: 469  EPAEFSCIVSDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGKANEGEYQFLVD 528

Query: 1182 NS--KCTAILTVEEPSINFTLRLPE---FILVPANTDAYLTVEIP-DETLDVTWY--KKK 1233
            +   K    +T    + + T+  P+    I+V A     L + I  D    ++W+  +K+
Sbjct: 529  SKDHKQPTGITATLKTYSVTIEKPQGEKEIVVKAGQKFTLDIPISGDPAPQMSWFLGEKE 588

Query: 1234 SVIEDT 1239
               E+T
Sbjct: 589  LYCENT 594



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 1/101 (0%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            S + S  P F   L  +    G T    C V G P+P+I WF+    I  +  ++M    
Sbjct: 1100 SRDVSQPPSFTLPLNNRKLTIGYTGTISCSVRGQPKPKIRWFKNKIEIIDNPKYKM-SAS 1158

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
              V  L IR     D GT+TC+A N  G  S   +++V  P
Sbjct: 1159 LGVVQLEIRRPRQADQGTYTCLAYNDHGEVSCDAQVMVREP 1199



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 68/312 (21%), Positives = 122/312 (39%), Gaps = 12/312 (3%)

Query: 1058 PKK-NKYDFEKRGHIRKLYIRNTSV-HDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115
            PKK  + D + RG ++K      S  H   +Y  +L+  + T +V       EI      
Sbjct: 225  PKKIQEEDLDFRGKLKKETTPKISFKHGLKDYRGMLKRMAATRKVNKRSNAYEIKLP-DT 283

Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAG 1174
            + V    K  FE  +       +WF++G EI   N H ++   G+ +KL I + +L D G
Sbjct: 284  ECVPNNGKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENANLMDDG 343

Query: 1175 EYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234
             +    G  K +  + V E     T    +  LV    DA  T  +          K   
Sbjct: 344  LFEIRAGEEKSSCEVHVLEAPTAVTKGFEDLQLVQGE-DAKFTATLSTAHGRFKILKDGI 402

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVD 1292
                 +  T+  D       I+K ++ D   Y      AKS  +L V+   V F  +  D
Sbjct: 403  EFGLNDNQTVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKSRFSD 462

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
                  +   ++ + +V   +  +   +W  N K +++ ++ +   D     L +K+V  
Sbjct: 463  VN--VNVNEPAEFSCIV---SDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGK 517

Query: 1353 TDAGIYKLRLEN 1364
             + G Y+  +++
Sbjct: 518  ANEGEYQFLVDS 529



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 3/134 (2%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVI 753
            +K  N     EG  T      E E    +  + K+ +  +PP    PL +  +  G +  
Sbjct: 1066 VKAQNEVGLSEGIATKDFAKIEKERLTYVKPEYKSRDVSQPPSFTLPLNNRKLTIGYTGT 1125

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSE 811
            +S  V G P+P I W KN   +   P      +  +  L+ ++ +  D+G YT  A N  
Sbjct: 1126 ISCSVRGQPKPKIRWFKNKIEIIDNPKYKMSASLGVVQLEIRRPRQADQGTYTCLAYNDH 1185

Query: 812  GIAETSAVITVEEP 825
            G     A + V EP
Sbjct: 1186 GEVSCDAQVMVREP 1199



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%)

Query: 1601 PPEVIWYKNG-NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            PP V W K   N++     Y I++++ +  +     K S S  YTI+ S+ AG  S    
Sbjct: 145  PPRVQWVKGKWNEITAGDRYQISSEKNSHTLTFSMPKMSDSGIYTIKVSSPAGLDSKTFE 204

Query: 1660 LKVYDKPSKPEGPVIMR 1676
            LKV  + S   G V++R
Sbjct: 205  LKVSPEKSASSGIVVVR 221



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 39/164 (23%), Positives = 66/164 (40%), Gaps = 10/164 (6%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
           I++  P  F  +     V+        C +V+  E    W F G+ +   ENI +  +  
Sbjct: 448 IVDSKPVAFKSRFSDVNVNVNEPAEFSC-IVSDAEVAGKWTFNGKPVEESENIQIIADGT 506

Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMI 745
                 VLK   V K  EG Y  +  +++ +    I   +KT     E PQ     K ++
Sbjct: 507 DRKL--VLK--EVGKANEGEYQFLVDSKDHKQPTGITATLKTYSVTIEKPQ---GEKEIV 559

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
           V+ G+   L   + G+P P ++W    K +    T S   T+ +
Sbjct: 560 VKAGQKFTLDIPISGDPAPQMSWFLGEKELYCENTPSGEFTNPL 603



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 11/114 (9%)

Query: 815  ETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN- 870
            E    +  E  + + ++PP F   +N  +++T+   GTI    R    P P I W++N  
Sbjct: 1089 ERLTYVKPEYKSRDVSQPPSFTLPLNN-RKLTIGYTGTISCSVR--GQPKPKIRWFKNKI 1145

Query: 871  EII-SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            EII +P   ++ +     +E+       + D G Y C+A N  G+ S  A+V +
Sbjct: 1146 EIIDNPKYKMSASLGVVQLEI---RRPRQADQGTYTCLAYNDHGEVSCDAQVMV 1196



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 2/96 (2%)

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
            + Q P  T+   +  +K  +G    ++  + G P P++ W+KN  ++ ++ +Y ++    
Sbjct: 1103 VSQPPSFTLPLNN--RKLTIGYTGTISCSVRGQPKPKIRWFKNKIEIIDNPKYKMSASLG 1160

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
               + I+  +++    YT  A N  G  S +  + V
Sbjct: 1161 VVQLEIRRPRQADQGTYTCLAYNDHGEVSCDAQVMV 1196


>UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus
            CG1915-PC, isoform C; n=1; Apis mellifera|Rep: PREDICTED:
            similar to sallimus CG1915-PC, isoform C - Apis mellifera
          Length = 4011

 Score =  150 bits (364), Expect = 4e-34
 Identities = 124/434 (28%), Positives = 192/434 (44%), Gaps = 41/434 (9%)

Query: 495  LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
            L +FEK   EE+ +AP F   ++P    +      EC V G P P++ W+R    +KP +
Sbjct: 2455 LVIFEK---EEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEELKPEK 2511

Query: 555  DFQMYYDDDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
              ++ ++ +   A L I E   ED   +   A N  G A     L++   +         
Sbjct: 2512 GREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVR-------- 2563

Query: 614  XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673
                         ++L    P  ++   A   + G  + L     + P P++ W   G E
Sbjct: 2564 ---------VSKPEVLRS--PKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAE 2612

Query: 674  IVP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKI--- 727
            IVP D+ +    E+   +Y     I  V K   G Y V   N  GEA  S  + +K    
Sbjct: 2613 IVPSDKRVIKIYENTTELY-----IPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKRED 2667

Query: 728  KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
            KT E + P+ IEPL+  IV +GE VI+  +V   P  +  W  + +P+++ P        
Sbjct: 2668 KTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQE 2727

Query: 788  SITILKPKKVKDE--GVYTLKAENSEGIAETSAVIT-VEEPTEENAE--PPLFINRFQEI 842
            + +IL  K++K E  G YT +AEN  G    +A I  ++ P EE  E   P F+ R   +
Sbjct: 2728 NKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPV 2787

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDS 901
             V +  +  L   V   P P + WY +N+ I   + IT   D E +  L IT V  E D+
Sbjct: 2788 RVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPE-DA 2846

Query: 902  GDYKCVASNSAGKS 915
            G+Y C A N  G++
Sbjct: 2847 GEYTCRAVNPVGEA 2860



 Score =  128 bits (310), Expect = 1e-27
 Identities = 127/494 (25%), Positives = 205/494 (41%), Gaps = 41/494 (8%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T +++ +AP F++KL+P      +T +F C V G P P+ITW+R    +  S+ + M   
Sbjct: 2360 TDKDKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTI- 2418

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
             +  A+L I +V  EDAG ++C A N AG A+ST  L++     +  +            
Sbjct: 2419 YETTASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMV 2478

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                  +LE I  T +  P+ ++   G + L        PE      F  E      +I 
Sbjct: 2479 EEHKPALLECI-VTGTPMPEVKWY-RGEEELK-------PEKGREITFNPETGEAKLHIL 2529

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEP 740
               E D  +Y    ++  V KF        + ++     S P VL+        P++  P
Sbjct: 2530 EPTEEDETIY----RVRAVNKFGRAECRANLVISNVVRVSKPEVLR-------SPKITRP 2578

Query: 741  LKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV 797
            L +++   G+ + LSA     P P + W +N     P      K   +T  + I +  K 
Sbjct: 2579 LPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTK- 2637

Query: 798  KDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
            KD G Y ++ EN  G A +S  +TV+  E   +  + P FI   Q   V E   + +  R
Sbjct: 2638 KDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETR 2697

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            V   P  S  W+ +   +  +  +          L+I  +  E  SG Y C A N  G  
Sbjct: 2698 VDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEY-SGTYTCRAENVGGSV 2756

Query: 916  SHGARV---------TIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNK 964
            +  A +         T+++   TFVK L       +G++  L C  Q   T   +WYH+ 
Sbjct: 2757 TCTATINLLDTPWEETVELVSPTFVKRL-SPVRVMDGESANLTCIVQGKPTPRVEWYHDN 2815

Query: 965  KEISGMDHREIIQE 978
            K I       I+Q+
Sbjct: 2816 KPIKEGKEITIVQD 2829



 Score =  120 bits (288), Expect = 6e-25
 Identities = 145/570 (25%), Positives = 237/570 (41%), Gaps = 57/570 (10%)

Query: 678  ENISVAIESDMHMY-CSVLKITNVKKFQEGTYTV----VAVN---REGEASLPIVLKIKT 729
            E I V +E ++      V++ T V+K  E    V    V V    R+ +    + + I  
Sbjct: 2302 EEIPVPVEKEVSTQEVQVIEATKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITD 2361

Query: 730  GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS 788
             +K+  P+ I+ L+ +I +   +   +  V GNP P ITW +N + + A          +
Sbjct: 2362 KDKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYET 2421

Query: 789  ITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
               L+  KVK+E  G+Y+ +A N  G+A ++  + + E  EE   P  F    + + V+E
Sbjct: 2422 TASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPH-FATPIKPLMVEE 2480

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYK 905
                 L   VT  P+P + WYR  E + P +     F+ E  E  +  ++ +E D   Y+
Sbjct: 2481 HKPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYR 2540

Query: 906  CVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYET--------EEGK--TVILECQTSH 954
              A N  G++   A + I +V +V+  + L+    T        E GK  T+  + ++  
Sbjct: 2541 VRAVNKFGRAECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKP 2600

Query: 955  TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTML 1010
            T   KWY N  EI   D R I                 D G  +  V+    +  +S  +
Sbjct: 2601 TPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSV 2660

Query: 1011 VVKE--------TIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN 1061
             VK+          P FI  LQ   V E +V I+E  ++S  TA   W  D   ++    
Sbjct: 2661 TVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLE-STP 2719

Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELP---------PE 1108
            +     + +   L I+       G Y+C    +    +CTA + +++ P         P 
Sbjct: 2720 QVRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPT 2779

Query: 1109 IITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIY 1166
             + RL   +V  G  A    I   K    V W+ D   I+    I +  D +    L I 
Sbjct: 2780 FVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAIT 2839

Query: 1167 DCDLDDAGEYSCE----VGNSKCTAILTVE 1192
            +   +DAGEY+C     VG + CT+ L VE
Sbjct: 2840 EVFPEDAGEYTCRAVNPVGEAVCTSSLIVE 2869



 Score =  116 bits (279), Expect = 7e-24
 Identities = 121/495 (24%), Positives = 199/495 (40%), Gaps = 46/495 (9%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            I P F +K +       +     C +   P P+I W    +E+   E   + I    +  
Sbjct: 2366 IAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTI----YET 2421

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQG 749
             + L+IT VK+   G Y+  A N  G A+  + L I   E+E   P    P+K ++V + 
Sbjct: 2422 TASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEH 2481

Query: 750  ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDT--HSITILKPKKVKDEGVYT 804
            +  +L   V G P P + W +     KP K      + +T    + IL+P + +DE +Y 
Sbjct: 2482 KPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTE-EDETIYR 2540

Query: 805  LKAENSEGIAETSA------VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            ++A N  G AE  A      V+ V +P  E    P        +  +    + L A    
Sbjct: 2541 VRAVNKFGRAECRANLVISNVVRVSKP--EVLRSPKITRPLPALVAEFGKPLTLSADFES 2598

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P + WYRN   I PS+           EL I  V  + D G Y+    N  G++   
Sbjct: 2599 KPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKK-DGGKYEVRVENPVGEARSS 2657

Query: 919  ARVTI--------DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEIS 968
              VT+        +V+   F++ LQ    T EG+ VI+E +     T S +W+H+ + + 
Sbjct: 2658 GSVTVKKREDKTDEVKAPRFIEPLQPQIVT-EGEVVIMETRVDSYPTASFQWFHDTRPLE 2716

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-----TSTMLVV----KETI--- 1016
                  I+ +                G   C  ++       T+T+ ++    +ET+   
Sbjct: 2717 STPQVRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELV 2776

Query: 1017 -PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074
             P F+++L    V + + A L   +  + T  V W  D + IK  K     +    +  L
Sbjct: 2777 SPTFVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSL 2836

Query: 1075 YIRNTSVHDEGEYSC 1089
             I      D GEY+C
Sbjct: 2837 AITEVFPEDAGEYTC 2851



 Score =  113 bits (272), Expect = 5e-23
 Identities = 156/636 (24%), Positives = 250/636 (39%), Gaps = 67/636 (10%)

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            V R  E  L  V K K  EK   + ++PLK    ++ E   +  + V      + W K  
Sbjct: 2247 VERIEEIVLKPVEKEKFEEKPKEEELKPLKLEKPKKLEEEEIEEEKVTE----MLWKKPE 2302

Query: 773  K-PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK----AENSEGIAETSAVITVEEPTE 827
            + PV      S  +   I   K +K+ ++ V   K     E+     +    + +    +
Sbjct: 2303 EIPVPVEKEVSTQEVQVIEATKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITDK 2362

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            +    P FI + Q +  + + T K    V  NP P ITWYRN + +  SE          
Sbjct: 2363 DKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETT 2422

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQ---KSYETEEG 943
              L IT V  E D+G Y C ASN AG ++    + I + E+     H     K    EE 
Sbjct: 2423 ASLEITKVKEE-DAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEH 2481

Query: 944  KTVILECQTSHT--VSTKWYHNKKEISGMDHREII---QEGRXXXXXXXXXXXXD-VGVI 997
            K  +LEC  + T     KWY  ++E+     REI    + G             + +  +
Sbjct: 2482 KPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRV 2541

Query: 998  KCIVK--DQETSTMLVVKETI----------PEFIRKLQDFEVKEKDVAILEVEINSE-T 1044
            + + K    E    LV+   +          P+  R L     +      L  +  S+ T
Sbjct: 2542 RAVNKFGRAECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPT 2601

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100
             +V W R+G  I P  +K   +   +  +LYI   +  D G+Y   +     +   +  V
Sbjct: 2602 PEVKWYRNGAEIVP-SDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSV 2660

Query: 1101 TVVE--------LPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNH 1151
            TV +          P  I  LQ Q V +G     E  + +   A  +WF D   ++ +  
Sbjct: 2661 TVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQ 2720

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAIL---------TVEEPSINF 1198
            +++     K  L I +   + +G Y+C      G+  CTA +         TVE  S  F
Sbjct: 2721 VRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTF 2780

Query: 1199 TLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIR 1256
              RL   + V     A LT  +  + T  V WY     I++ ++ T++ D +   +L I 
Sbjct: 2781 VKRLSP-VRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAIT 2839

Query: 1257 KCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288
            +   +D  EYTC  +    +A  T+ L VE  E+ P
Sbjct: 2840 EVFPEDAGEYTCRAVNPVGEAVCTSSLIVEAYEYVP 2875



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 34/380 (8%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P   W  N + +   +    +I   +ASL I KV+  DAG+Y  R  N  G A   +N
Sbjct: 2395 PFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPAGVATSTVN 2454

Query: 1375 VTILDKP--------SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426
            + I +K         + P KP ++E    ++  C      T    + +Y  E +E+   +
Sbjct: 2455 LVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECI--VTGTPMPEVKWYRGE-EELKPEK 2511

Query: 1427 WISVKNITKT-QTSIQNLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETK---IQ 1480
               +    +T +  +  L+        +R  AVN+   ++         V++ +K   ++
Sbjct: 2512 GREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVRVSKPEVLR 2571

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536
            SP + +PL  +  E  + + L+  F   P P+V WYR+G ++    K     YEN     
Sbjct: 2572 SPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELY 2631

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------- 1586
                       Y+    N  GE  +S  V ++++   T   +++K    +          
Sbjct: 2632 IPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKT---DEVKAPRFIEPLQPQIVTE 2688

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+  ++   ++  P     W+ +   LE+  +  I T+E  S++ IKE+K  +S  YT  
Sbjct: 2689 GEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEYSGTYTCR 2748

Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666
            A N  G+ +   T+ + D P
Sbjct: 2749 AENVGGSVTCTATINLLDTP 2768



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 59/191 (30%), Positives = 86/191 (45%), Gaps = 17/191 (8%)

Query: 508  MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
            ++P FV++L P    DG +    C V+G P P++ W+     IK  ++  +  D + V +
Sbjct: 2776 VSPTFVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCS 2835

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA----PLSDHGSEMTVXXXXXXXXXX 623
            L I EVFPEDAG +TC A N  G A  T+ LIVEA    P S+  S + V          
Sbjct: 2836 LAITEVFPEDAGEYTCRAVNPVGEAVCTSSLIVEAYEYVPDSEIASSI-VATSLTTGQSG 2894

Query: 624  XXADIL------------EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671
               D+L            E  P    K P+      G    LE ++   P+P+  W  +G
Sbjct: 2895 SEEDLLSPKETPLFDTDEESAPEIVKKLPQLIPTKVGELTRLEVKVKGKPKPEGKWYKQG 2954

Query: 672  EEIVPDENISV 682
             EIV  +   +
Sbjct: 2955 VEIVSSQEFLI 2965



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 74/273 (27%), Positives = 114/273 (41%), Gaps = 26/273 (9%)

Query: 468  WVPAQYLMDENNYTQYLQKKLNE--KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS 525
            ++P     D   Y   ++  + E      + V ++    ++  AP F+E L+P+   +G 
Sbjct: 2631 YIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVTEGE 2690

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
             V  E +V+ YP     WF  T  ++ +   ++    +N + L+I+E+ PE +GT+TC A
Sbjct: 2691 VVIMETRVDSYPTASFQWFHDTRPLESTPQVRI-VTQENKSILMIKEIKPEYSGTYTCRA 2749

Query: 586  KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
            +N  G  + T  +     L D   E TV                E + PTF K+     V
Sbjct: 2750 ENVGGSVTCTATI----NLLDTPWEETV----------------ELVSPTFVKRLSPVRV 2789

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
             +G    L C +   P P + W    + I   E   + I  D    CS L IT V     
Sbjct: 2790 MDGESANLTCIVQGKPTPRVEWYHDNKPI--KEGKEITIVQDTEGVCS-LAITEVFPEDA 2846

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
            G YT  AVN  GEA     L ++  E  P   I
Sbjct: 2847 GEYTCRAVNPVGEAVCTSSLIVEAYEYVPDSEI 2879



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 190/857 (22%), Positives = 327/857 (38%), Gaps = 86/857 (10%)

Query: 718  EASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--P 774
            E  L  + K K  E++P +V ++P+K +   + E  +++ + V   +P     +  K  P
Sbjct: 2004 EVKLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPEEEKPEEVKLKP 2063

Query: 775  VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            VK LP + +        +KPK+ K E V       S  ++E      VEE  E+ AE  L
Sbjct: 2064 VKRLPKEEEEKE-----VKPKEEKPEEVKLKPIPKS--VSEK-----VEEKPEDEAEKIL 2111

Query: 835  FINRFQEITVKEKGTIKLVARVTRNPVPS---ITWYRNNEIISPSETITQNFDGENIELV 891
               R +    K K  +     VT  P+     IT   + EI    + + Q  + + I   
Sbjct: 2112 PWRRGK----KTKKIVDFREEVTVVPIDQEKVITEIHDEEI----KIVEQKVEAKKI--- 2160

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
               V +EI   ++K        +++   +  I+ EKV  V+ ++     +E + VI +  
Sbjct: 2161 ---VQAEIK--EFKEEKPELPWRTTKEVKEIIE-EKVV-VEEIKPETVLKEDE-VIEDVT 2212

Query: 952  TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--QETSTM 1009
             S  VS  W   +K       +E+++               ++ V+K + K+  +E    
Sbjct: 2213 ESSEVS--WRKRRKPKKPEKEKEVVELKPVEKHEEFVERIEEI-VLKPVEKEKFEEKPKE 2269

Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAIL----EVEINSETADVVWERDGEIIKPKKNKYDF 1065
              +K    E  +KL++ E++E+ V  +      EI       V  ++ ++I+  K +   
Sbjct: 2270 EELKPLKLEKPKKLEEEEIEEEKVTEMLWKKPEEIPVPVEKEVSTQEVQVIEATKVEKIV 2329

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125
            E    + K   +   V D             +      ++ P  I +LQ         A 
Sbjct: 2330 EDVVEVEK---KKVQVEDRRRKHKQRTQVEISITDKDKKIAPRFIQKLQPVIAQPETTAK 2386

Query: 1126 FEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
            F   +       + W+++  E+  S    +TI      L+I     +DAG YSC   N  
Sbjct: 2387 FTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPA 2446

Query: 1185 CTAILTV-------EEPSINFTLRLP-EFILVPANTDAYLTVEIPDETL-DVTWYKKKSV 1235
              A  TV       EE  I      P + ++V  +  A L   +    + +V WY+ +  
Sbjct: 2447 GVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEE 2506

Query: 1236 I--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-------EF 1286
            +  E   + T   +  +  L I + TE+D+  Y    ++     + +  +V         
Sbjct: 2507 LKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVRVSK 2566

Query: 1287 P-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            P     PKI         + G  +TL  D+++ P P  +W  N   I         I   
Sbjct: 2567 PEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYEN 2626

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNILEIDSSSIN 1398
            +  L I +V   D G Y++R+EN  G A    +VT+    DK      P  +E     I 
Sbjct: 2627 TTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQI- 2685

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKNITKTQTSIQNLKTNSSYRFRAY 1454
            +   E          Y    +Q    T  +     V+ +T+   SI  +K         Y
Sbjct: 2686 VTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEYSGTY 2745

Query: 1455 AVNEVDISDASETTEYYKVI----KET-KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
                 ++  +   T    ++    +ET ++ SPT  K L  +     E   LTCI  G P
Sbjct: 2746 TCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCIVQGKP 2805

Query: 1510 QPKVTWYRDGKKLKTAK 1526
             P+V WY D K +K  K
Sbjct: 2806 TPRVEWYHDNKPIKEGK 2822



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 78/309 (25%), Positives = 124/309 (40%), Gaps = 35/309 (11%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  +      E  P P++ W+R  A I PS D ++    +N   L I EV  +D G +  
Sbjct: 2587 GKPLTLSADFESKPTPEVKWYRNGAEIVPS-DKRVIKIYENTTELYIPEVTKKDGGKYEV 2645

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
              +N  G A S+  + V+    D   E+                      P F +  + Q
Sbjct: 2646 RVENPVGEARSSGSVTVKKR-EDKTDEVKA--------------------PRFIEPLQPQ 2684

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             V EG  +++E R+ + P     W      +     + +  + +     S+L I  +K  
Sbjct: 2685 IVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENK----SILMIKEIKPE 2740

Query: 704  QEGTYTVVAVNREGEASLPIVLKI------KTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
              GTYT  A N  G  +    + +      +T E   P  ++ L  + V  GES  L+  
Sbjct: 2741 YSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCI 2800

Query: 758  VVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIA 814
            V G P P + W  +NKP+K         DT  +  L   +V  +D G YT +A N  G A
Sbjct: 2801 VQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEYTCRAVNPVGEA 2860

Query: 815  ETSAVITVE 823
              ++ + VE
Sbjct: 2861 VCTSSLIVE 2869



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 153/719 (21%), Positives = 274/719 (38%), Gaps = 71/719 (9%)

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            V ++ EA   +  +IK  ++E P++  P ++   ++ + +I    VV   +P  T  K +
Sbjct: 2151 VEQKVEAKKIVQAEIKEFKEEKPEL--PWRT--TKEVKEIIEEKVVVEEIKPE-TVLKED 2205

Query: 773  KPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLK-AENSEGIAETSAVITVEEPTEENA 830
            + ++ +   S+         KPKK  K++ V  LK  E  E   E    I ++   +E  
Sbjct: 2206 EVIEDVTESSEVSWRKRR--KPKKPEKEKEVVELKPVEKHEEFVERIEEIVLKPVEKEKF 2263

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            E        + + +++   ++    +    V  + W +  EI  P E      + + IE 
Sbjct: 2264 EEKPKEEELKPLKLEKPKKLE-EEEIEEEKVTEMLWKKPEEIPVPVEKEVSTQEVQVIEA 2322

Query: 891  VITN--VDSEIDSGDYKCVASNSAGKSSHGARVTIDV----EKVT--FVKHLQKSYETEE 942
                  V+  ++    K    +   K     +V I +    +K+   F++ LQ      E
Sbjct: 2323 TKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITDKDKKIAPRFIQKLQPVIAQPE 2382

Query: 943  GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
              T    C    +      WY N++E+   +   +                 D G+  C 
Sbjct: 2383 -TTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCR 2441

Query: 1001 VKDQE---TSTM-LVVKET-----IPEFIRKLQDFEVKEKDVAILE-VEINSETADVVWE 1050
              +     TST+ LV+ E       P F   ++   V+E   A+LE +   +   +V W 
Sbjct: 2442 ASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWY 2501

Query: 1051 RDGEIIKPKKNK-YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVEL 1105
            R  E +KP+K +   F       KL+I   +  DE  Y     ++     C A + +  +
Sbjct: 2502 RGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNV 2561

Query: 1106 ----PPEI-----ITR-LQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQL 1154
                 PE+     ITR L       G   T   +  +K    V+W+++G+EI  S+   +
Sbjct: 2562 VRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVI 2621

Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT-LRLPEFI--- 1206
             I     +L I +    D G+Y   V    G ++ +  +TV++       ++ P FI   
Sbjct: 2622 KIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPL 2681

Query: 1207 ---LVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
               +V       +   +    T    W+     +E T +  +++   K  L+I++   + 
Sbjct: 2682 QPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEY 2741

Query: 1263 QCEYTCVL--LDAKSTTKLKVEVVEFP---------PKIVDYEREYRIKRGSDVTLLVDY 1311
               YTC    +    T    + +++ P         P  V      R+  G    L    
Sbjct: 2742 SGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCIV 2801

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHA 1369
            Q  P P  EW  ++K IK+ K      D++   SL I +V   DAG Y  R  N  G A
Sbjct: 2802 QGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEYTCRAVNPVGEA 2860



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 70/286 (24%), Positives = 113/286 (39%), Gaps = 25/286 (8%)

Query: 1420 QEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
            QE+  +E +I     T     I  +K   +  +   A N   +  A+ T       KE +
Sbjct: 2406 QELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPAGV--ATSTVNLVIFEKEEE 2463

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXX 1535
              +P    P+K +  E ++   L CI  G P P+V WYR  ++LK  K    T+      
Sbjct: 2464 GIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGE 2523

Query: 1536 XXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV------ 1586
                           Y+  A N  G  E  C   +    V+ +S  ++ +  K+      
Sbjct: 2524 AKLHILEPTEEDETIYRVRAVNKFGRAE--CRANLVISNVVRVSKPEVLRSPKITRPLPA 2581

Query: 1587 -----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                 G    ++A  E  P PEV WY+NG ++    +  I   E T+ + I E+ +    
Sbjct: 2582 LVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKKDGG 2641

Query: 1642 KYTIEASNTAG--TSSVEVTLKV-YDKPSKPEGPVIMREISRESVT 1684
            KY +   N  G   SS  VT+K   DK  + + P  +  +  + VT
Sbjct: 2642 KYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVT 2687



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 100/520 (19%), Positives = 188/520 (36%), Gaps = 38/520 (7%)

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
            F  +L   I  P  T  +      +   ++TWY+ +  +  +EK+ +       +L I K
Sbjct: 2370 FIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITK 2429

Query: 1258 CTEDDQCEYTCVLLD----AKSTTKLKV---EVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
              E+D   Y+C   +    A ST  L +   E     P      +   ++      L   
Sbjct: 2430 VKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECI 2489

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGH 1368
                P P  +W    + +K  K  + + + ++    +  +E T  D  IY++R  N  G 
Sbjct: 2490 VTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGR 2549

Query: 1369 ADVEMNVTI-----LDKPSPPGKPNI------LEIDSSSINICWDEPENTGNSTIIYYVV 1417
            A+   N+ I     + KP     P I      L  +         + E+     + +Y  
Sbjct: 2550 AECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRN 2609

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKE 1476
              + + + + +       T+  I  +      ++     N V +   +   T   +  K 
Sbjct: 2610 GAEIVPSDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKT 2669

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENR 1532
             ++++P   +PL+       E + +       P     W+ D + L++       T EN+
Sbjct: 2670 DEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENK 2729

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP----VITISNEDIKQKHKV-- 1586
                           Y C A N  G V  +  + +   P    V  +S   +K+   V  
Sbjct: 2730 SILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRV 2789

Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKY 1643
              G+   +T +++G P P V WY +   ++  KE  I    E    + I E+    + +Y
Sbjct: 2790 MDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEY 2849

Query: 1644 TIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            T  A N  G    TSS+ V    Y   S+    ++   ++
Sbjct: 2850 TCRAVNPVGEAVCTSSLIVEAYEYVPDSEIASSIVATSLT 2889



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 99/414 (23%), Positives = 165/414 (39%), Gaps = 50/414 (12%)

Query: 1380 KPSPPGKPNILEIDSSSIN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            K   P K    EI+   +  + W +PE       +   V  QE+   E   V+ I +   
Sbjct: 2276 KLEKPKKLEEEEIEEEKVTEMLWKKPEEI--PVPVEKEVSTQEVQVIEATKVEKIVEDVV 2333

Query: 1439 SIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
             ++  K     R R +    +V+IS            K+ KI    ++K L+ +  +P  
Sbjct: 2334 EVEKKKVQVEDRRRKHKQRTQVEISITD---------KDKKIAPRFIQK-LQPVIAQPET 2383

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
              + TC   G P P++TWYR+ ++L    K     YE                 Y C A 
Sbjct: 2384 TAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRAS 2443

Query: 1554 NDHGEVETSCVVGIQQKPVITISNE---DIK----QKHKVGDEWLVTAVIEGIPPPEVIW 1606
            N  G   ++  + I +K    I+      IK    ++HK     L+  ++ G P PEV W
Sbjct: 2444 NPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPA---LLECIVTGTPMPEVKW 2500

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK--YTIEASNTAGTSSVEVTLKVYD 1664
            Y+   +L+ +K   IT   +T   ++  L+ +   +  Y + A N  G +     L + +
Sbjct: 2501 YRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISN 2560

Query: 1665 --KPSKPE---GPVIMREISRESVTIEWKPPL------DDGGLELTKYAIEKHE--PDNN 1711
              + SKPE    P I R +   ++  E+  PL      +       K+     E  P + 
Sbjct: 2561 VVRVSKPEVLRSPKITRPL--PALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDK 2618

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
            R IK+   +   E Y I ++ +     + V  +NPVG  EA  S  + +K   D
Sbjct: 2619 RVIKI--YENTTELY-IPEVTKKDGGKYEVRVENPVG--EARSSGSVTVKKRED 2667



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 38/108 (35%), Positives = 58/108 (53%), Gaps = 7/108 (6%)

Query: 496  PVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            P+F+  T EE   AP  V+KL P+  P   G   + E +V+G P+P+  W++Q   I  S
Sbjct: 2906 PLFD--TDEES--APEIVKKL-PQLIPTKVGELTRLEVKVKGKPKPEGKWYKQGVEIVSS 2960

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            Q+F +   +D  + L I E +P+D G       N  G +++TT L VE
Sbjct: 2961 QEFLIEEFEDGTSVLTIAETYPDDMGEIVFEVHNPLGVSTTTTYLSVE 3008



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 1/103 (0%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            E+ T       P F++++   +  +G T  FEC   G P P + W++   +I  + + ++
Sbjct: 3487 ERGTMSATQSVPRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKI 3546

Query: 559  -YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
               D++    L I+    ED  T+ C A +  G  ++  +L V
Sbjct: 3547 RLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKLHV 3589



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSIT 790
            P+ I+ +  +  ++GE+ +      GNP P + W KN+K +   P       D +  +I 
Sbjct: 3498 PRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKIRLLDEEKKTIL 3557

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN--RFQEITVKEK 847
             +K    +D+  Y  KA +  G+  T A + V E T +     +F++  +F+E  V+EK
Sbjct: 3558 TIKHATEEDDATYVCKATSEIGLTTTKAKLHVTEITGKK----IFMDEEQFEEQIVEEK 3612



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 7/136 (5%)

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            H E E   +   Q  P       D+  K   G+  +   +  G P P+V+WYKN   + N
Sbjct: 3483 HSEDERGTMSATQSVPRFIQEITDVYAKE--GETAVFECIYSGNPVPDVVWYKNDKMIIN 3540

Query: 1616 --DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
              + +  +  +EK +++ IK       + Y  +A++  G ++ +  L V +   K    +
Sbjct: 3541 TPNVKIRLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKLHVTEITGK---KI 3597

Query: 1674 IMREISRESVTIEWKP 1689
             M E   E   +E KP
Sbjct: 3598 FMDEEQFEEQIVEEKP 3613



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 1226 DVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
            DV WYK   +I +T   K  L+ + KK  L I+  TE+D   Y C        +TTK K+
Sbjct: 3528 DVVWYKNDKMIINTPNVKIRLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKL 3587

Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK--IIKKCKHTKPSID 1339
             V E   K +  + E   ++      +V+ +   +P +E     K   +KK K TK  + 
Sbjct: 3588 HVTEITGKKIFMDEEQFEEQ------IVEEKPKKKPEEEKPHKKKKPEMKKAKETKEKVK 3641

Query: 1340 SKSASLTIKKV 1350
             +   +  K++
Sbjct: 3642 GERVKIDKKEL 3652



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 3/111 (2%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELV 891
            P FI    ++  KE  T       + NPVP + WY+N++ II+      +  D E   ++
Sbjct: 3498 PRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKIRLLDEEKKTIL 3557

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
                 +E D   Y C A++  G ++  A+  + V ++T  K      + EE
Sbjct: 3558 TIKHATEEDDATYVCKATSEIGLTTTKAK--LHVTEITGKKIFMDEEQFEE 3606



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 48/236 (20%), Positives = 94/236 (39%), Gaps = 7/236 (2%)

Query: 167  KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNK 226
            KP+  +P +  ++  K  PK  EE E+ +     +  E PE+   P++ +   T     +
Sbjct: 1262 KPEEEKPEEVKLKPVKRLPK--EEEEKEMVTLKPVKKEKPEE-EKPEEVKLKPTKKEKPE 1318

Query: 227  RSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRI 286
              K   +K++  +      +  E V                      + +LPK + +  +
Sbjct: 1319 EEKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEV 1378

Query: 287  KYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLF 346
              +T  P +  KP       +K   +  R  KE  + +     P K    E+ + E+   
Sbjct: 1379 --VTLKPVKKEKPEEEKPEEVKLKPV-KRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKL 1435

Query: 347  SYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIK 402
                 +  +++E E++  K   +E P+E+ PE+  + P K    K +E  + VT+K
Sbjct: 1436 KPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVK-RLPKEEEEKEVVTLK 1490



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKY 1643
            KVG+   +   ++G P PE  WYK G ++ + +E+ I   ++ TSV+ I E       + 
Sbjct: 2929 KVGELTRLEVKVKGKPKPEGKWYKQGVEIVSSQEFLIEEFEDGTSVLTIAETYPDDMGEI 2988

Query: 1644 TIEASNTAGTSSVEVTLKV 1662
              E  N  G S+    L V
Sbjct: 2989 VFEVHNPLGVSTTTTYLSV 3007



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 82/374 (21%), Positives = 150/374 (40%), Gaps = 29/374 (7%)

Query: 45   RKLQIEELESSKPQHPEEMTVP--QFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIR 102
            +K +++ LE SKP+ PE+  V    F             Q     KLP+   +  IK + 
Sbjct: 922  KKPELKPLEKSKPEAPEKEKVQLKPFQREKPEEKLTIISQ-----KLPEKTQEKEIKEVE 976

Query: 103  D--WPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKS--DL 158
            +  W  +  KP ++    +++  E     K                 L+ +  EK   + 
Sbjct: 977  EISWRRKPKKPSISEESPVEKVAEKIVEEKVIKKEEETIEDFKSIA-LKPIKREKKPEER 1035

Query: 159  FDSQEDESKPDVS-QPPQNIIEEAKSEPKLIEE--SEQPIAKTSEIDNEVPEKINVPDDK 215
             D +E   KP    +  +   EE K +PK IE+  +E PI +    + +V      P +K
Sbjct: 1036 EDKEEIILKPVKHIKKEEESTEEIKLKPKSIEQKVTEIPIEEKKVEEEQVEVSWRKPREK 1095

Query: 216  ETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQ-FXXXXXXXXXXXXXXETSL 274
               +      K    T IK++ +E+       +E ++ P+ F                  
Sbjct: 1096 VMKEVQK--EKVEDFTAIKLKPEEIIEEVTLKSEKLEKPETFENGEILEEKTELPWRRGK 1153

Query: 275  VKLPKFQLK-SRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKL 333
             KL K ++K  +I  +     +S++  I +    ++        KE +++K +     + 
Sbjct: 1154 KKLAKEEVKLEQILKLEKQVSKSVEEQIIFKHKDEK-----PEEKEISEIKLKPVKHIEK 1208

Query: 334  PDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKID 393
            P  EK E E  L   + +   +++E E++  K   +E P+E+ PE   + P K   +  +
Sbjct: 1209 PKEEKPE-EVKLKPVKRL-PKEEEEKEVVTLKPIKKEKPEEEKPE-LKLKPVKHIEKPEE 1265

Query: 394  EIVDEVTIK--KRL 405
            E  +EV +K  KRL
Sbjct: 1266 EKPEEVKLKPVKRL 1279



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 71/327 (21%), Positives = 126/327 (38%), Gaps = 18/327 (5%)

Query: 86   VVKLPKFQLKSRI---KFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXX 142
            V +LPK + +  +   K I+   P+E KP    L  +K+  +     KE           
Sbjct: 1573 VKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPK-EEEEKEVITLKPVKKEK 1631

Query: 143  XXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKT--SE 200
                  E V L+       +E+E +    +P   + +E   E K  E   +P+ +    E
Sbjct: 1632 PEEEKPEEVKLKPVKRLPKEEEEKEVVTLKP---VKKEKPEEEKPEEVKLKPVKRLPKEE 1688

Query: 201  IDNEVPEKINVPDDKETSQTPTSFN-KRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXX 259
             + EV     V  +K   + P     K  K  P + E K++E    +  E V        
Sbjct: 1689 EEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKKVE---EEEKEVVTLKPIKKE 1745

Query: 260  XXXXXXXXXXXETSLVKLPKFQLKSRI---KYITSWPPESIKPLISYMGSIKQNGILSRN 316
                          + +LPK + +  +   K +    PE  KP    +  +K+       
Sbjct: 1746 KPEEEKPEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEE 1805

Query: 317  IKEAAKVKKQVFVPP-KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKED 375
             K   + K+ V + P K    E+ + E+        +  +++E E+I  K   +E P+E+
Sbjct: 1806 KKVEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLHKEEEEKEVITLKPVKKEKPEEE 1865

Query: 376  VPEQYTITPRKSSAQKIDEIVDEVTIK 402
             PE+  + P K   ++ DE  + VT+K
Sbjct: 1866 KPEEVKLKPVKRLHKEEDE-KEVVTLK 1891



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 720  SLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVK 776
            +L  V K K  E++P +V ++P+K +   + E  +++ + +   +P     +  K  PV+
Sbjct: 1853 TLKPVKKEKPEEEKPEEVKLKPVKRLHKEEDEKEVVTLKPLKKEKPEEEKPEEVKLKPVQ 1912

Query: 777  ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             LP + +         KP++VK + V  L  E  E    T   I  E+P EE  E
Sbjct: 1913 RLPKEEEEKEEKPKEEKPEEVKLKPVKHLPKEEEENEVVTLKPIKKEKPEEEKPE 1967



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 720  SLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVK 776
            +L  + K K  E++P +V ++P+K +   + E  +++ + +   +P     +  K  PV+
Sbjct: 1452 TLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVQ 1511

Query: 777  ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             LP + +         KP++VK + V  L  E  E    T   I  E+P EE  E
Sbjct: 1512 RLPKEEEEKEEKPKEEKPEEVKLKPVKHLPKEEEEKEVVTLKPIKKEKPEEEKPE 1566



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 52/241 (21%), Positives = 94/241 (39%), Gaps = 13/241 (5%)

Query: 160  DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219
            + +E E KP   +P +  ++  K  PK  EE E  +     I  E PE+   P++ +   
Sbjct: 1917 EEEEKEEKPKEEKPEEVKLKPVKHLPK--EEEENEVVTLKPIKKEKPEE-EKPEEVKLKP 1973

Query: 220  TPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPK 279
                  +  +   + ++  + E  T +  E V                      + +LPK
Sbjct: 1974 VKRLPKEEEEKEVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEEEKPEEVKLKPVKRLPK 2033

Query: 280  FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKT 339
             + +  +  +T  P +  KP        K   +  + +K   K +++  V PK    E+ 
Sbjct: 2034 EEEEKEV--VTLKPVKKEKP-----EEEKPEEVKLKPVKRLPKEEEEKEVKPKEEKPEEV 2086

Query: 340  ELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQKIDEIVD 397
            +L+  P    E + E  +DE E I   +  ++  K  D  E+ T+ P     + I EI D
Sbjct: 2087 KLKPIPKSVSEKVEEKPEDEAEKILPWRRGKKTKKIVDFREEVTVVP-IDQEKVITEIHD 2145

Query: 398  E 398
            E
Sbjct: 2146 E 2146



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 7/126 (5%)

Query: 729  TGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDG 784
            T E+  P++++ L  +I  + GE   L  +V G P+P   W K    +   +    +   
Sbjct: 2910 TDEESAPEIVKKLPQLIPTKVGELTRLEVKVKGKPKPEGKWYKQGVEIVSSQEFLIEEFE 2969

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEI 842
            D  S+  +      D G    +  N  G++ T+  ++VE    T+E  +P  ++ + +E+
Sbjct: 2970 DGTSVLTIAETYPDDMGEIVFEVHNPLGVSTTTTYLSVEGIVGTKEYRKPS-WVTQMEEM 3028

Query: 843  TVKEKG 848
                +G
Sbjct: 3029 QEALRG 3034


>UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep:
            Hemicentin-2 - Homo sapiens (Human)
          Length = 1340

 Score =  150 bits (364), Expect = 4e-34
 Identities = 228/992 (22%), Positives = 393/992 (39%), Gaps = 92/992 (9%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK--SMIVRQGESV 752
            L++  V     GTY+ VAV+  GEA     L +     EPP + +  +   + +  G  +
Sbjct: 369  LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM----EPPHIEDSGQPTELSLTPGAPM 424

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--KVKDEGVYTLKAENS 810
             L     G P+P ITW K+ + +    T+ + ++ +  +L+ +  +V+D G+YT  AE+ 
Sbjct: 425  ELLCDAQGTPQPNITWHKDGQAL----TRLENNSRATRVLRVENVQVRDAGLYTCLAESP 480

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G  E S  + V+ P   N   P    RF  +     G + L   V   P P ITW+R+ 
Sbjct: 481  AGAIEKSFRVRVQAPP--NIVGPRG-PRF--VVGLAPGQLVLECSVEAEPAPKITWHRDG 535

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
             I+   +  TQ F      L +  + S  DSGDY C A N+AG +S   RV  ++  V  
Sbjct: 536  -IVLQEDAHTQ-FPERGRFLQLQAL-STADSGDYSCTARNAAGSTSVAFRV--EIHTVPT 590

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHR-EIIQEGRXXXXXXX 987
            ++    +      +T +L CQ     +    W  ++  +     R EI+ EG        
Sbjct: 591  IRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQ 647

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046
                 D G   C+  +   S             R+ +D  V    +A+L  E + S    
Sbjct: 648  PVLAQDAGHYLCLASNSAGSD------------RQGRDLRV----LALLPCEASGSPKPL 691

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVV 1103
            VVW +DG+ +  +  +  +        L +      D  ++ C++ +E   A       V
Sbjct: 692  VVWWKDGQKLDFRLQQGAYRLLPS-NALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV 750

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEI-QFSNHIQLTIDGKKQ 1161
             +PP I     +  V            T   A  V W K G+++    +  +++  G   
Sbjct: 751  HVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG--- 807

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
             L+I       AG Y+C   NS   A     LTV+   +     LP  +   A  +  L 
Sbjct: 808  ALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPV--VKPLPSVVRAVAEEEVLLP 865

Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
             E   IP  T  +TW K+   +       ++   + R   I   + +D   Y C+  ++ 
Sbjct: 866  CEASGIPRPT--ITWQKEGLNVATGVSTQVLPGGQLR---IAHASPEDAGNYLCIAKNSA 920

Query: 1275 STTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
             +   K   VV+ PP I +   +     GS   L    +  P+PN  W  + + +   + 
Sbjct: 921  GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE- 979

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393
             K +I   S  L +K +E  DAG Y    EN  G A   +++TIL  P     P    + 
Sbjct: 980  GKFTI-QPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLR 1038

Query: 1394 SSSINICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
                +  W      G+ T  I + V  + +  TE +S ++   T      +    S  + 
Sbjct: 1039 LG--DRLWLRCAARGSPTPRIGWTVNDRPV--TEGVSEQDGGSTLQRAA-VSREDSGTYV 1093

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQP 1511
             +A N V  + A      +  +KE    +P ++    +   EP    I+L C+  G P P
Sbjct: 1094 CWAENRVGRTQAVS----FVHVKE----APVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 1145

Query: 1512 KVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
             + W +DG  L+ +   ++                  Y+C+A N+ G  +   ++ +Q  
Sbjct: 1146 DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 1205

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            PV  +  +D+  +   GD+  +     G P P + W + G  L   +   + T    S +
Sbjct: 1206 PVFQVEPQDMTVRS--GDDVALRCQATGEPTPTIEWLQAGQPLRASR--RLRTLPDGS-L 1260

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             ++ ++   +  Y   A N  G+++    L V
Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score =  105 bits (253), Expect = 1e-20
 Identities = 128/565 (22%), Positives = 222/565 (39%), Gaps = 51/565 (9%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PPT +       V   + ++L C    IP P ++W   G ++    +      S     
Sbjct: 752  VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPS----- 806

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L+I        G YT  A N  G A   + L ++        V++PL S++    E 
Sbjct: 807  -GALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASP-----VVKPLPSVVRAVAEE 860

Query: 752  -VILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDTHSITILKPKKVKDEGVYTLKAE 808
             V+L  +  G PRPTITW K    V   + T+   G    I    P   +D G Y   A+
Sbjct: 861  EVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASP---EDAGNYLCIAK 917

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            NS G A     + V+        PP+  N   +++  E     L  +   +P P+ITW +
Sbjct: 918  NSAGSAMGKTRLVVQ-------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK 970

Query: 869  NNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            + + +S +E   T    G   EL++ N++ + D+G Y C A N+ G++     +TI V  
Sbjct: 971  DGQPVSGAEGKFTIQPSG---ELLVKNLEGQ-DAGTYTCTAENAVGRARRRVHLTILVLP 1026

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            V       +S    +   +    + S T    W  N + ++      + ++         
Sbjct: 1027 VFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT----EGVSEQDGGSTLQRA 1082

Query: 988  XXXXXDVGVIKCIVKDQETSTMLV----VKETIPEFIRKLQDFEVKEKDVAI-LEVEINS 1042
                 D G   C  +++   T  V    VKE  P    +   + V+    +I L+  +  
Sbjct: 1083 AVSREDSGTYVCWAENRVGRTQAVSFVHVKEA-PVLQGEAFSYLVEPVGGSIQLDCVVRG 1141

Query: 1043 E-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-- 1099
            +   D+ W +DG  ++    ++  +       L I  T   D G Y C+  +E   A+  
Sbjct: 1142 DPVPDIHWIKDGLPLRGSHLRHQLQN----GSLTIHRTERDDAGRYQCLAENEMGVAKKV 1197

Query: 1100 -VTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157
             + V++  P      Q+  V  G+      + T +    + W + G  ++ S  ++   D
Sbjct: 1198 VILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPD 1257

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN 1182
            G    L + + +  DAG Y C   N
Sbjct: 1258 G---SLWLENVETGDAGTYDCVAHN 1279



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 102/463 (22%), Positives = 183/463 (39%), Gaps = 41/463 (8%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            ++LL C    IP P I W  +G       N++  + + + +    L+I +      G Y 
Sbjct: 861  EVLLPCEASGIPRPTITWQKEGL------NVATGVSTQV-LPGGQLRIAHASPEDAGNYL 913

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
             +A N  G A     L ++     PP +   L  +   +G    L  +  G+P P ITW 
Sbjct: 914  CIAKNSAGSAMGKTRLVVQV----PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWD 969

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            K+ +PV     K         ++K  + +D G YT  AEN+ G A     +T+       
Sbjct: 970  KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI------- 1022

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
               P+F     + +++    + L      +P P I W  N+  +  +E +++   G  ++
Sbjct: 1023 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV--TEGVSEQDGGSTLQ 1080

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVIL 948
                   S  DSG Y C A N  G++   A   + V++   ++    SY  E  G ++ L
Sbjct: 1081 RAAV---SREDSGTYVCWAENRVGRTQ--AVSFVHVKEAPVLQGEAFSYLVEPVGGSIQL 1135

Query: 949  EC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-- 1004
            +C  +        W  +   + G   R  +Q G             D G  +C+ +++  
Sbjct: 1136 DCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDAGRYQCLAENEMG 1192

Query: 1005 -ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNK 1062
                 +++V ++ P F  + QD  V+  D   L  +   E T  + W + G+ ++  +  
Sbjct: 1193 VAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL 1252

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTVV 1103
                       L++ N    D G Y C+  +   S TA   +V
Sbjct: 1253 RTLPD----GSLWLENVETGDAGTYDCVAHNLLGSATARAFLV 1291



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 75/290 (25%), Positives = 122/290 (42%), Gaps = 23/290 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F+  P  + +  G  + L C     P P I W      +   E +S   E D     S
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EGVS---EQDGG---S 1077

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L+   V +   GTY   A NR G       + +K   + P    E    ++   G S+ 
Sbjct: 1078 TLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK---EAPVLQGEAFSYLVEPVGGSIQ 1134

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L   V G+P P I W K+  P++    +      S+TI + ++  D G Y   AEN  G+
Sbjct: 1135 LDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTER-DDAGRYQCLAENEMGV 1193

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A+   ++ ++       EP       Q++TV+    + L  + T  P P+I W +  + +
Sbjct: 1194 AKKVVILVLQSAPVFQVEP-------QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 1246

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              S  +    DG    L + NV++  D+G Y CVA N  G ++  A + +
Sbjct: 1247 RASRRLRTLPDGS---LWLENVETG-DAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 131/641 (20%), Positives = 229/641 (35%), Gaps = 50/641 (7%)

Query: 1035 ILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            +LE  + +E A  + W RDG +++   +   F +RG  R L ++  S  D G+YSC  R+
Sbjct: 516  VLECSVEAEPAPKITWHRDGIVLQEDAHT-QFPERG--RFLQLQALSTADSGDYSCTARN 572

Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQ-F 1148
             + +  V     +   P I +      V+    A    +     A LV W KD   +   
Sbjct: 573  AAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPR 632

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
            S   ++  +G    L+I      DAG Y C   NS                LR+    L+
Sbjct: 633  SPRFEILPEGS---LRIQPVLAQDAGHYLCLASNS-------AGSDRQGRDLRV--LALL 680

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
            P           P     V W+K    ++   +      +    L++      D  ++ C
Sbjct: 681  PCEASGS-----PKPL--VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFEC 733

Query: 1269 VLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            V+  +     +L    V  PP I D + ++ +   + V L       P P   W      
Sbjct: 734  VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 793

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +   + +   + S S +L I +     AG Y     N+ G A   + +T+   P     P
Sbjct: 794  LG-ARGSGYRV-SPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLP 851

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
            +++   +    +   E       TI +   + + ++    +S + +   Q  I +     
Sbjct: 852  SVVRAVAEEEVLLPCEASGIPRPTITW---QKEGLNVATGVSTQVLPGGQLRIAHASPED 908

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            +  +   A N    S   +T    +V        P +E  L +++T       L C   G
Sbjct: 909  AGNYLCIAKNSAG-SAMGKTRLVVQV-------PPVIENGLPDLSTTEGSHAFLPCKARG 960

Query: 1508 VPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
             P+P +TW +DG+ +  A  K T +                 Y C A N  G       +
Sbjct: 961  SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 1020

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             I   PV T    D  +  ++GD   +     G P P + W  N   +       ++ ++
Sbjct: 1021 TILVLPVFTTLPGD--RSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTE----GVSEQD 1074

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
              S ++   + R  S  Y   A N  G +     + V + P
Sbjct: 1075 GGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 1115



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 50/216 (23%), Positives = 96/216 (44%), Gaps = 7/216 (3%)

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLK--NITTEPNEDIELTCIFGGVPQPKVTWY 1516
            V +S+A E   ++++   T ++ P +E   +   ++  P   +EL C   G PQP +TW+
Sbjct: 385  VAVSEAGEARRHFQL---TVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 441

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            +DG+ L   +                     Y C+A +  G +E S  V +Q  P I   
Sbjct: 442  KDGQALTRLENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP 501

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636
                        + ++   +E  P P++ W+++G  L+ D        E+   ++++ L 
Sbjct: 502  RGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQF--PERGRFLQLQALS 559

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             + S  Y+  A N AG++SV   ++++  P+   GP
Sbjct: 560  TADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 595



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 72/292 (24%), Positives = 130/292 (44%), Gaps = 32/292 (10%)

Query: 632 IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           +PPTF + PK + V +  GS ++L C +  +P P + WL   ++ +P E+ +V     + 
Sbjct: 35  VPPTF-ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAV---HGVV 87

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                L+++ ++  Q GTYT VA N + EA    V+ +    +     +   +   V +G
Sbjct: 88  SRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV--AREHHVLEG 145

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYT 804
           + V L  +  G P P + W K+  P+       L    DG +    +LK     D G YT
Sbjct: 146 QEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS---LVLKGLWASDAGAYT 202

Query: 805 LKAENSEG-IAETSAVITVEEPT-EENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             A N  G  A    V  +  PT ++ A+     ++R  E+       + +V  V  +P 
Sbjct: 203 CVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL-------VTMVCPVRGSPP 255

Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             ++W ++   +  S+    +  G  + +    +    D+G + CVA++ AG
Sbjct: 256 IHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQL---ADAGIFTCVAASPAG 304



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 7/195 (3%)

Query: 1482 PTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXX 1538
            PT E P  + ++      + LTC   GVP P VTW +D   ++++               
Sbjct: 37   PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLS 96

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVI 1596
                     Y C+A N   E     VV +   P I  S   + ++H V  G E  +    
Sbjct: 97   RLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG--VAREHHVLEGQEVRLDCEA 154

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            +G PPP+V W K+G+ L  D   ++        + +K L  S +  YT  A N AG  + 
Sbjct: 155  DGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDAR 214

Query: 1657 EVTLKVYDKPSKPEG 1671
              T+ V   P+  +G
Sbjct: 215  LHTVNVLVPPTIKQG 229



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 129/627 (20%), Positives = 225/627 (35%), Gaps = 55/627 (8%)

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-I 850
            ++  +V D+G+Y+ K  N  G A  +  +TV+ P       P F N   E   +  G+ +
Sbjct: 3    IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP-------PTFENPKTETVSQVAGSPL 55

Query: 851  KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
             L   V+  P P++TW ++   +  S        G  ++L          +G Y CVA N
Sbjct: 56   VLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQ---PAQAGTYTCVAEN 112

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEIS 968
            +  ++     V + V        + + +   EG+ V L+C+          W  +   + 
Sbjct: 113  TQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL- 171

Query: 969  GMD---HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKL 1023
            G D   H     +G             D G   C+  +   E + +  V   +P  I++ 
Sbjct: 172  GQDMGPHLRFYLDG--GSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQG 229

Query: 1024 QD----FEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
             D       +  ++  +   +  S    V W +DG +  P   +      GH   L I  
Sbjct: 230  ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSGH--TLRISK 286

Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-- 1136
              + D G ++C+    +  A+       P   +R  ++       A +     +  A   
Sbjct: 287  VQLADAGIFTCVAASPAGVADRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPC 346

Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILT 1190
               R  KDG  +  S  ++     +   L++      D+G YSC    E G ++    LT
Sbjct: 347  LSCRGMKDGEPL-LSQSLE-----QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT 400

Query: 1191 V-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
            V E P I  + +  E  L P      L         ++TW+K    +   E     +   
Sbjct: 401  VMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN----NSRA 456

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG---SDV 1305
             R L +      D   YTC+        +    V V+ PP IV   R  R   G     +
Sbjct: 457  TRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-PRGPRFVVGLAPGQL 515

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
             L    +A P P   W  +  ++++  HT+     +   L ++ +   D+G Y     N 
Sbjct: 516  VLECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGRFLQLQALSTADSGDYSCTARNA 573

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEI 1392
             G   V   V I   P+    P  + +
Sbjct: 574  AGSTSVAFRVEIHTVPTIRSGPPAVNV 600



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 62/284 (21%), Positives = 112/284 (39%), Gaps = 24/284 (8%)

Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
           S +P    +  G+ + L C     P+P+I W   G+ +   EN S A          VL+
Sbjct: 410 SGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR--------VLR 461

Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVIL 754
           + NV+    G YT +A +  G       ++++     PP ++ P   + ++      ++L
Sbjct: 462 VENVQVRDAGLYTCLAESPAGAIEKSFRVRVQA----PPNIVGPRGPRFVVGLAPGQLVL 517

Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
              V   P P ITW ++   ++        +      L+     D G Y+  A N+ G  
Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 577

Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
             +  + +       + PP        + V    T  L  +    P P ++W ++   + 
Sbjct: 578 SVAFRVEIHTVPTIRSGPPA-------VNVSVNQTALLPCQADGVPAPLVSWRKDRVPLD 630

Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
           P     +     ++   I  V ++ D+G Y C+ASNSAG    G
Sbjct: 631 PRSPRFEILPEGSLR--IQPVLAQ-DAGHYLCLASNSAGSDRQG 671



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 59/227 (25%), Positives = 95/227 (41%), Gaps = 19/227 (8%)

Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESV 752
           L+I   +   +G Y+    N  GEA     L ++     PP    P K+  V Q  G  +
Sbjct: 1   LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV----PPTFENP-KTETVSQVAGSPL 55

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAEN 809
           +L+  V G P PT+TW K+  PV++       S G    ++ L+P +    G YT  AEN
Sbjct: 56  VLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQA---GTYTCVAEN 112

Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
           ++  A    V+ V       +         +E  V E   ++L       P P + W ++
Sbjct: 113 TQAEARKDFVVAVLVAPRIRSS-----GVAREHHVLEGQEVRLDCEADGQPPPDVAWLKD 167

Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              +         F  +   LV+  + +  D+G Y CVA N AG+ +
Sbjct: 168 GSPLGQDMGPHLRFYLDGGSLVLKGLWAS-DAGAYTCVAHNPAGEDA 213



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 47/190 (24%), Positives = 75/190 (39%), Gaps = 10/190 (5%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKL--KTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            L C   G P+P V W++DG+KL  +  +  Y                    ++C+  N+ 
Sbjct: 680  LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 739

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-EN 1615
            GE      V +   P I     D           ++T    GIP P V W K G +L   
Sbjct: 740  GEAHRLYQVTVHVPPTIADDQTDFTVTMMA--PVVLTCHSTGIPAPTVSWSKAGAQLGAR 797

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
               Y ++    +  + I +    H+ +YT  A N+AG +   V L V   P     P ++
Sbjct: 798  GSGYRVSP---SGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVV 854

Query: 1676 REISRESVTI 1685
            R ++ E V +
Sbjct: 855  RAVAEEEVLL 864



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 45/176 (25%), Positives = 78/176 (44%), Gaps = 7/176 (3%)

Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
           +  +V EG ++ L+C     P PD+AWL  G  +  D    +    D       L +  +
Sbjct: 138 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD----GGSLVLKGL 193

Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
                G YT VA N  GE +    + +        Q  +   +++ R GE V +   V G
Sbjct: 194 WASDAGAYTCVAHNPAGEDARLHTVNVLV-PPTIKQGADGSGTLVSRPGELVTMVCPVRG 252

Query: 761 NPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
           +P   ++W K+  P+  +  T   G  H++ I K  ++ D G++T  A +  G+A+
Sbjct: 253 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISK-VQLADAGIFTCVAASPAGVAD 307



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 4/77 (5%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
           V   C+  G PRP ITW ++   +      Q+         L I    PEDAG + C+AK
Sbjct: 862 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAK 917

Query: 587 NAAGFASSTTELIVEAP 603
           N+AG A   T L+V+ P
Sbjct: 918 NSAGSAMGKTRLVVQVP 934



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
           R  H  +G  V+ +C+ +G P P + W +  + +       + +  D   +LV++ ++  
Sbjct: 138 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG-GSLVLKGLWAS 196

Query: 577 DAGTFTCVAKNAAG 590
           DAG +TCVA N AG
Sbjct: 197 DAGAYTCVAHNPAG 210



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 54/228 (23%), Positives = 91/228 (39%), Gaps = 11/228 (4%)

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
            L+I +  + D G YSC+V N    A+    LTV+ P   F     E +   A +   LT 
Sbjct: 1    LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPP-TFENPKTETVSQVAGSPLVLTC 59

Query: 1219 EIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            ++       VTW K +  +E +    ++S  +   L + +        YTCV  + ++  
Sbjct: 60   DVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVAENTQAEA 117

Query: 1278 KLK-VEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            +   V  V   P+I      RE+ +  G +V L  +    P P+  W+ +   + +    
Sbjct: 118  RKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGP 177

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
                     SL +K +  +DAG Y     N  G       V +L  P+
Sbjct: 178  HLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 225



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+    L    T +GS     C+  G P P ITW +     +P    +  +       L+
Sbjct: 935  PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG---QPVSGAEGKFTIQPSGELL 991

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            ++ +  +DAGT+TC A+NA G A     L +
Sbjct: 992  VKNLEGQDAGTYTCTAENAVGRARRRVHLTI 1022



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
            AP+F  + +      G  V   CQ  G P P I W +    ++ S+  +   D     +L
Sbjct: 1205 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPD----GSL 1260

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
             +  V   DAGT+ CVA N  G A++   L+V
Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            Y C+A ++ GE      + + + P I  S +  +     G    +    +G P P + W+
Sbjct: 382  YSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 441

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            K+G  L    E N      T V+R++ ++   +  YT  A + AG       ++V   P+
Sbjct: 442  KDGQALTR-LENN---SRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPN 497

Query: 1668 --KPEGP 1672
               P GP
Sbjct: 498  IVGPRGP 504



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 9/171 (5%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIA 1552
            +++ L C   G P P V W +DG  L          Y +                Y C+A
Sbjct: 146  QEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVA 205

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV--IEGIPPPEVIWYKNG 1610
             N  GE      V +   P I    +          E LVT V  + G PP  V W K+G
Sbjct: 206  HNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGE-LVTMVCPVRGSPPIHVSWLKDG 264

Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
              L   +   +     T  +RI +++ + +  +T  A++ AG +    TL+
Sbjct: 265  LPLPLSQRTLLHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQ 313



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 16/149 (10%)

Query: 522  PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            P G ++Q +C V G P P I W +      P +   + +   N  +L I     +DAG +
Sbjct: 1128 PVGGSIQLDCVVRGDPVPDIHWIKDGL---PLRGSHLRHQLQN-GSLTIHRTERDDAGRY 1183

Query: 582  TCVAKNAAGFASSTTELIVE-APLSD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
             C+A+N  G A     L+++ AP+      +MTV             D+      T    
Sbjct: 1184 QCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGD---------DVALRCQATGEPT 1234

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWL 668
            P  +++  G  +    RL  +P+  + WL
Sbjct: 1235 PTIEWLQAGQPLRASRRLRTLPDGSL-WL 1262



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 3/64 (4%)

Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           EC VE  P P+ITW R   +++     Q     +    L ++ +   D+G ++C A+NAA
Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQEDAHTQF---PERGRFLQLQALSTADSGDYSCTARNAA 574

Query: 590 GFAS 593
           G  S
Sbjct: 575 GSTS 578



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 10/85 (11%)

Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR--EVFPEDA 578
           TP G+ ++  C  +G P+P ITW +    +          ++++ AT V+R   V   DA
Sbjct: 419 TP-GAPMELLCDAQGTPQPNITWHKDGQALTR-------LENNSRATRVLRVENVQVRDA 470

Query: 579 GTFTCVAKNAAGFASSTTELIVEAP 603
           G +TC+A++ AG    +  + V+AP
Sbjct: 471 GLYTCLAESPAGAIEKSFRVRVQAP 495



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 7/95 (7%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  +P+   V  G D+ L C+    P P I WL  G+ +     +    +        
Sbjct: 1206 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS------ 1259

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
             L + NV+    GTY  VA N  G A+    L ++
Sbjct: 1260 -LWLENVETGDAGTYDCVAHNLLGSATARAFLVVR 1293



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 5/80 (6%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           T    CQ +G P P ++W +    + P S  F++  +     +L I+ V  +DAG + C+
Sbjct: 605 TALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE----GSLRIQPVLAQDAGHYLCL 660

Query: 585 AKNAAGFASSTTELIVEAPL 604
           A N+AG      +L V A L
Sbjct: 661 ASNSAGSDRQGRDLRVLALL 680



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS +   C V G P P +TW +      P +   ++        L +  + P  AGT+TC
Sbjct: 52  GSPLVLTCDVSGVPAPTVTWLKDR---MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 108

Query: 584 VAKN 587
           VA+N
Sbjct: 109 VAEN 112



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 3/89 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V   C V G P   ++W +    +  SQ   ++       TL I +V   DAG FTC
Sbjct: 241 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGH---TLRISKVQLADAGIFTC 297

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMT 612
           VA + AG A     L      S   S MT
Sbjct: 298 VAASPAGVADRNFTLQCPLSWSRWSSRMT 326


>UniRef50_Q4SM88 Cluster: Chromosome 3 SCAF14553, whole genome shotgun
            sequence; n=6; Euteleostomi|Rep: Chromosome 3 SCAF14553,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 2007

 Score =  149 bits (362), Expect = 6e-34
 Identities = 207/1032 (20%), Positives = 407/1032 (39%), Gaps = 76/1032 (7%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C  V+  + ++ W   G EI P EN+++  +  M      L I +      G+YT 
Sbjct: 848  VVLLCH-VSAEDAEVTWYKDGCEIHPSENVTLQADGTMRR----LIIRSADTSDAGSYTC 902

Query: 711  VAVNREGEASLPI-VLKIKTGEKEPP-QVIEPLKSMIVRQ--GESVILSAQVVGNPRPTI 766
             A N   E S+ I    + +   EPP  ++EP   +++ +   E + L  + +      +
Sbjct: 903  WAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCE-LSRSSGKV 961

Query: 767  TWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             W K+ +PV+  P     S+G    ++IL    V D G Y  +++      +    +TV+
Sbjct: 962  RWYKDGQPVEESPNLQLISEGPYRRLSIL-TGTVNDGGEYVCESDGDSVFFQ----LTVK 1016

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            +P      P        E+T      ++L   +++   P + W+R+   +    ++    
Sbjct: 1017 DPPVRIISPS---ESELELTHVAPERLELSCEISKVEAP-VRWFRDGLEVKEGPSLRLEA 1072

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943
            DG    L+I  V +  D+G+Y C   + +   +    VT    K++  +++ +  ++  G
Sbjct: 1073 DGAQRRLIIP-VTTVDDTGEYACDTEDDS--VAFMVTVTEPPVKLSRPQNMPEKLDSHAG 1129

Query: 944  KTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            + ++LE + S      KW+ N  E+    +  +  +G             D G   C V 
Sbjct: 1130 EPIVLETEVSRPNAVVKWWLNGSEMVESGNVTMTTDGVIHRLTIHSPSPEDSGKYSCDVI 1189

Query: 1003 DQETSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
            D +    + V E   + +RK +   +      D  +LE E++       W ++   ++  
Sbjct: 1190 DDKMDFHVTVTEPPVKILRKSEMETELRFLVSDDIVLECELSRANVGAKWYKNNSSVEGD 1249

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
            + +Y  E+ G    L I N  + D G+Y    +D++ + +VTV E P   + R  +  V 
Sbjct: 1250 E-RYCEEEEGAFCSLVILNAGLEDSGKYFLDAKDDNISFDVTVEEPPVTFLNREDDVVVT 1308

Query: 1120 --KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
              +    T    ++K  A+VRW K  +  +     Q  ++G K+   I      DAGEY 
Sbjct: 1309 GYEAESVTLTTYVSKESAIVRWLKAWTAAE-GERFQARMEGHKRTFTIDPLKRSDAGEYI 1367

Query: 1178 CEVGNSKCTAILTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
            C++   +    L V+ P  + F   L    ++      +  V  PD+ + + W      I
Sbjct: 1368 CDINTDQIHFSLLVKVPRVVEFLTELHNTTVLEGEDATFKCVVSPDD-VHLVWLMDNEPI 1426

Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296
               +++    +    TL+I+KC   D  + T       S   LKV+  E           
Sbjct: 1427 ALGDRYQATQNGLCHTLVIKKCQMLDCSKITAEAEGQISKAILKVQ--EAQVMFTKKTDA 1484

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
               +   + TL  +  +      +W+    +I+       + +  +  LTI  +  +D G
Sbjct: 1485 VMAEEFGEATLETEI-SIETGEVQWMRQGVVIQPGPRHTLAQNGCTRRLTIHNLTISDRG 1543

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             Y  R E       V++NV          +P  + I  +  +      + T       + 
Sbjct: 1544 TY--RCETLHDRTQVKLNV----------EPRKICIRKALTD------QETYERETASFE 1585

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            VE    D  E I  K+  + + + Q  + +++ R  +  ++ + + D        + ++ 
Sbjct: 1586 VELSHTD-VEGIWQKDGIRVKPNNQ-WRVSTNGRVHSLTLSNLTLEDTGSVVFSAEGVRT 1643

Query: 1477 TK----IQSP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY 1529
            T      ++P ++ K L +I  E +    L C F      +V W+++G +L+  K    Y
Sbjct: 1644 TARLTVRETPVSILKTLSDIRVEEDFPATLECEFSR-QIIEVRWFKNGAELRPGKNCRIY 1702

Query: 1530 E--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKV 1586
                +               Y C    D GE+ TSC + + + K  I    ED+  +   
Sbjct: 1703 STGRKRFCQIMQCSRADSGTYTC----DTGEMNTSCTLEVYEHKLEIMQDLEDLYIQEDQ 1758

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
               ++    +E +      WYK+G+K+       I ++     + +  +K   + +    
Sbjct: 1759 NAVFMCEVSLEEVAGE---WYKDGHKIRPSSTIKIRSEGTKHFLLMCNVKAEDAGEIRFT 1815

Query: 1647 ASNTAGTSSVEV 1658
            A +    + +EV
Sbjct: 1816 ARDVESIAYLEV 1827



 Score =  140 bits (338), Expect = 5e-31
 Identities = 169/735 (22%), Positives = 282/735 (38%), Gaps = 42/735 (5%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            DI+LEC L +       W      +  DE      E +   +CS++ I N      G Y 
Sbjct: 1223 DIVLECEL-SRANVGAKWYKNNSSVEGDERYC---EEEEGAFCSLV-ILNAGLEDSGKYF 1277

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG---ESVILSAQVVGNPRPTI 766
            + A  ++   S  + ++      EPP      +  +V  G   ESV L+  V       +
Sbjct: 1278 LDA--KDDNISFDVTVE------EPPVTFLNREDDVVVTGYEAESVTLTTYV-SKESAIV 1328

Query: 767  TWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             W K     +      + +G   + TI  P K  D G Y     N++ I   S ++ V  
Sbjct: 1329 RWLKAWTAAEGERFQARMEGHKRTFTI-DPLKRSDAGEYICDI-NTDQI-HFSLLVKVPR 1385

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
              E       F+      TV E         V+ + V  + W  +NE I+  +      +
Sbjct: 1386 VVE-------FLTELHNTTVLEGEDATFKCVVSPDDV-HLVWLMDNEPIALGDRYQATQN 1437

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
            G    L  T V  +    D   + + + G+ S  A + +   +V F K        E G+
Sbjct: 1438 G----LCHTLVIKKCQMLDCSKITAEAEGQISK-AILKVQEAQVMFTKKTDAVMAEEFGE 1492

Query: 945  TVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
               LE + S  T   +W      I       + Q G             D G  +C    
Sbjct: 1493 AT-LETEISIETGEVQWMRQGVVIQPGPRHTLAQNGCTRRLTIHNLTISDRGTYRCETLH 1551

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
              T   L V+       + L D E  E++ A  EVE++    + +W++DG  +KP  N++
Sbjct: 1552 DRTQVKLNVEPRKICIRKALTDQETYERETASFEVELSHTDVEGIWQKDGIRVKPN-NQW 1610

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
                 G +  L + N ++ D G           TA +TV E P  I+  L + +V +   
Sbjct: 1611 RVSTNGRVHSLTLSNLTLEDTGSVVFSAEGVRTTARLTVRETPVSILKTLSDIRVEEDFP 1670

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            AT E E ++    VRWFK+G+E++   + ++   G+K+  +I  C   D+G Y+C+ G  
Sbjct: 1671 ATLECEFSRQIIEVRWFKNGAELRPGKNCRIYSTGRKRFCQIMQCSRADSGTYTCDTGEM 1730

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
              +  L V E  +     L E + +  + +A    E+  E +   WYK    I  +    
Sbjct: 1731 NTSCTLEVYEHKLEIMQDL-EDLYIQEDQNAVFMCEVSLEEVAGEWYKDGHKIRPSSTIK 1789

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
            + S+  K  L++     +D  E      D +S   L+VE  E P  IV   R+ R     
Sbjct: 1790 IRSEGTKHFLLMCNVKAEDAGEIRFTARDVESIAYLEVE--ELPVSIVKPLRD-RTALEK 1846

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
               +L    +  +    W  + K +      +   D  S  L I++V   D G Y + + 
Sbjct: 1847 HRVILECTVSSARCCATWYKDGKEVVPSDRVEILDDGCSLKLVIQEVAVEDEGTYSVEVG 1906

Query: 1364 NNCGHADVEMNVTIL 1378
             +   A + +    L
Sbjct: 1907 EHTSKAKLMVEAQAL 1921



 Score =  132 bits (319), Expect = 1e-28
 Identities = 159/705 (22%), Positives = 293/705 (41%), Gaps = 53/705 (7%)

Query: 705  EGTYT--VVAVN---REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            EG Y   V  +N   R G    P V+ +  G    P++   LKS  V +GE    S Q+ 
Sbjct: 616  EGNYRFRVCCINKYGRSGHVEFPKVVHLVPG----PKIQNCLKSCEVAEGEDAHFSIQL- 670

Query: 760  GNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
             +     TW  N+   +P      +     HS+ I +    +D+   T  A    G+ + 
Sbjct: 671  -STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIAN---GVRD- 725

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            SA + V  P E    P    +  + +   +   I L   V+ +P   ++W+++ + +  +
Sbjct: 726  SAPLHVR-PVEVKFSPLSDTDGNKRVETGD--AIVLYCEVS-HPFAQVSWFKDGKELLMT 781

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            + +    +G+   +VI + D+   +G Y C  S    +  +   V     +   V   + 
Sbjct: 782  DDLNIQSEGKMRRVVIQSADAS-HAGVYTCETSGDIIR--YNVEVAGPPVEFCPVPEEEL 838

Query: 937  SYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
               + E   V+L C  S       WY +  EI   ++  +  +G             D G
Sbjct: 839  HKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 898

Query: 996  VIKCIVKDQETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAI---LEVEINSET 1044
               C   +      + ++           P  I + +D  V E+ V+    L+ E++  +
Sbjct: 899  SYTCWAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCELSRSS 958

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W +DG+ ++   N       G  R+L I   +V+D GEY C    +S   ++TV +
Sbjct: 959  GKVRWYKDGQPVEESPN-LQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKD 1017

Query: 1105 LPPEIITRLQNQ-KVNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
             P  II+  +++ ++        E+  E++K +A VRWF+DG E++    ++L  DG ++
Sbjct: 1018 PPVRIISPSESELELTHVAPERLELSCEISKVEAPVRWFRDGLEVKEGPSLRLEADGAQR 1077

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVE 1219
            +L I    +DD GEY+C+  +     ++TV EP +  +    +PE +   A     L  E
Sbjct: 1078 RLIIPVTTVDDTGEYACDTEDDSVAFMVTVTEPPVKLSRPQNMPEKLDSHAGEPIVLETE 1137

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +      V W+   S + ++   T+ +D     L I   + +D  +Y+C ++D K     
Sbjct: 1138 VSRPNAVVKWWLNGSEMVESGNVTMTTDGVIHRLTIHSPSPEDSGKYSCDVIDDK--MDF 1195

Query: 1280 KVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             V V E P KI+   + E E R     D+ L  +         +W  N+  ++  +    
Sbjct: 1196 HVTVTEPPVKILRKSEMETELRFLVSDDIVLECELSR-ANVGAKWYKNNSSVEGDERYCE 1254

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              +    SL I      D+G Y L  +++    ++  +VT+ + P
Sbjct: 1255 EEEGAFCSLVILNAGLEDSGKYFLDAKDD----NISFDVTVEEPP 1295



 Score =  111 bits (268), Expect = 2e-22
 Identities = 124/562 (22%), Positives = 226/562 (40%), Gaps = 37/562 (6%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F+KK  A   +E  +  LE   ++I   ++ W+ +G  I P    ++A           L
Sbjct: 1478 FTKKTDAVMAEEFGEATLETE-ISIETGEVQWMRQGVVIQPGPRHTLAQNGCTRR----L 1532

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             I N+     GTY    ++   +  L +       E     + + L      + E+    
Sbjct: 1533 TIHNLTISDRGTYRCETLHDRTQVKLNV-------EPRKICIRKALTDQETYERETASFE 1585

Query: 756  AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             ++       I W K+    KP       ++G  HS+T L    ++D G     AE    
Sbjct: 1586 VELSHTDVEGI-WQKDGIRVKPNNQWRVSTNGRVHSLT-LSNLTLEDTGSVVFSAEG--- 1640

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
               T+A +TV E       P   +    +I V+E     L    +R  +  + W++N   
Sbjct: 1641 -VRTTARLTVRET------PVSILKTLSDIRVEEDFPATLECEFSRQII-EVRWFKNGAE 1692

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            + P +       G      I    S  DSG Y C      G+ +    + +   K+  ++
Sbjct: 1693 LRPGKNCRIYSTGRKRFCQIMQC-SRADSGTYTC----DTGEMNTSCTLEVYEHKLEIMQ 1747

Query: 933  HLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
             L+  Y  E+   V + C+ S   V+ +WY +  +I      +I  EG            
Sbjct: 1748 DLEDLYIQEDQNAVFM-CEVSLEEVAGEWYKDGHKIRPSSTIKIRSEGTKHFLLMCNVKA 1806

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051
             D G I+   +D E+   L V+E     ++ L+D    EK   ILE  ++S      W +
Sbjct: 1807 EDAGEIRFTARDVESIAYLEVEELPVSIVKPLRDRTALEKHRVILECTVSSARCCATWYK 1866

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111
            DG+ + P  ++ +    G   KL I+  +V DEG YS  + + +  A++ V      ++ 
Sbjct: 1867 DGKEVVPS-DRVEILDDGCSLKLVIQEVAVEDEGTYSVEVGEHTSKAKLMVEAQALVVVK 1925

Query: 1112 RLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
             L++ +V + + A+F+ +++   +    W  +G  +Q    + L   G   KL++     
Sbjct: 1926 HLEDLEVTEPDAASFQCQVSVAINKPPVWTLNGENLQPGPWVHLENHGTTYKLRLKSTST 1985

Query: 1171 DDAGEYSCEVGNSKCTAILTVE 1192
            D +G     +G ++ +A LTV+
Sbjct: 1986 DMSGVVKFTLGKARSSASLTVK 2007



 Score =  105 bits (251), Expect = 2e-20
 Identities = 202/1033 (19%), Positives = 398/1033 (38%), Gaps = 105/1033 (10%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-------PTK 781
            + + +P  +I+PL S+ V +GE    S ++ G P P + W K+ K +  +        ++
Sbjct: 146  SSDDKPRFLIKPL-SLRVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISE 204

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA----------- 830
             DG    + I + + + D+GVYT +A N  G A   AV+ VE   E  A           
Sbjct: 205  QDGGWFQLRIYRTR-MPDKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTS 263

Query: 831  -------------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
                         EPP+ +++ ++  V E    K    VT  P P I W ++   +    
Sbjct: 264  RLLPKHRSHKAALEPPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGR 323

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
                  D E    +      E D+G Y C ASN+ G +     +++      F + L K 
Sbjct: 324  RHLIFEDREGYYTLKVLYCKEKDTGLYVCAASNALGNTLSAVHLSVKGSAGKFRRPL-KD 382

Query: 938  YETEEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
             E  E    +LEC     +V   WY   + +       + Q+G             D GV
Sbjct: 383  VEVRERDVAVLECDVPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTIRDVAADDDGV 442

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
              C + D   S   + + T    ++     EV E + A+  VE+ ++  ++ W +DG + 
Sbjct: 443  YLCEIPDGAKS---IAELT----VKGRSKLEVMEGENAMFCVEVENDEEEIHWFKDG-LQ 494

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDES-------------CTAEV 1100
              + ++   +  G    L   N +  D G  + +    R  S             C AE 
Sbjct: 495  LHEMHQVILKSFGKTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEA 554

Query: 1101 TV-VELP-PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158
            T+ V+ P   ++            ++ F +E+ +  +   W K  +  + +   ++T DG
Sbjct: 555  TMDVDRPNSALLAWAPAPNSPTSTRSIFVVEMQEVGS-QEWLKCFTS-ETATSAEVTGDG 612

Query: 1159 K--KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
               +   +   C ++  G  S  V   K   +  V  P I   L+  E   V    DA+ 
Sbjct: 613  VQCEGNYRFRVCCINKYGR-SGHVEFPK--VVHLVPGPKIQNCLKSCE---VAEGEDAHF 666

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAKS 1275
            ++++   T+  TW+   + ++   +F++     K +L+I +    +D+ E T +    + 
Sbjct: 667  SIQL-STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRD 725

Query: 1276 TTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
            +  L V  VE  F P + D +   R++ G  + L  +  + P     W  + K +     
Sbjct: 726  SAPLHVRPVEVKFSP-LSDTDGNKRVETGDAIVLYCEV-SHPFAQVSWFKDGKELLMTDD 783

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM---NVTILDKPSPPGKPNIL 1390
                 + K   + I+  + + AG+Y      +    +VE+    V     P      + +
Sbjct: 784  LNIQSEGKMRRVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSM 843

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSY 1449
            E+D   + +C    E   ++ + +Y  +  EI  +E ++++ + T  +  I++  T+ + 
Sbjct: 844  ELD-PVVLLCHVSAE---DAEVTWY-KDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 898

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE--PNEDIELTCIFGG 1507
             +  +A N  +  + S       V          + +P  ++  E   +EDI L C    
Sbjct: 899  SYTCWAGN--NSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCELSR 956

Query: 1508 VPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
                KV WY+DG+ ++ +                         + +  +D   V     V
Sbjct: 957  -SSGKVRWYKDGQPVEESPNLQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTV 1015

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
                  +I+ S  +++  H   +   ++  I  +  P V W+++G +++      +    
Sbjct: 1016 KDPPVRIISPSESELELTHVAPERLELSCEISKVEAP-VRWFRDGLEVKEGPSLRLEADG 1074

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPE-------GPVIM 1675
                + I       + +Y  +  + +    V VT   +K+    + PE        P+++
Sbjct: 1075 AQRRLIIPVTTVDDTGEYACDTEDDSVAFMVTVTEPPVKLSRPQNMPEKLDSHAGEPIVL 1134

Query: 1676 R-EISRESVTIEW 1687
              E+SR +  ++W
Sbjct: 1135 ETEVSRPNAVVKW 1147



 Score =  102 bits (244), Expect = 1e-19
 Identities = 132/624 (21%), Positives = 247/624 (39%), Gaps = 45/624 (7%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KL 1163
            PP  +++ +   V +G  A F   +T K    + W KDG  ++      +  D +    L
Sbjct: 278  PPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGRRHLIFEDREGYYTL 337

Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            K+  C   D G Y C     +GN+     L+V+  +  F   L + + V     A L  +
Sbjct: 338  KVLYCKEKDTGLYVCAASNALGNTLSAVHLSVKGSAGKFRRPLKD-VEVRERDVAVLECD 396

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTK 1278
            +PDE++   WY +   +    K+ +     +R L IR    DD   Y C + D AKS  +
Sbjct: 397  VPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTIRDVAADDDGVYLCEIPDGAKSIAE 456

Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
            L V+             +  +  G +    V+ +   +    W  +   + +        
Sbjct: 457  LTVKG----------RSKLEVMEGENAMFCVEVEN-DEEEIHWFKDGLQLHEMHQVILKS 505

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS-SSI 1397
              K+  L    V + D+G+       +   + +++  +    P  P +   +++D  +S 
Sbjct: 506  FGKTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEAT-MDVDRPNSA 564

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454
             + W    N+  ST   +VVE QE+ + EW+     +  T  + +   ++   +YRFR  
Sbjct: 565  LLAWAPAPNSPTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVC 624

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED----IELTCIFGGVPQ 1510
             +N+      S   E+ KV+    +  P ++  LK+      ED    I+L+    G   
Sbjct: 625  CINKYG---RSGHVEFPKVVH--LVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG--- 676

Query: 1511 PKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQ 1568
               TW+ +  +L+   + + E R                K  + F  +G V  S  + ++
Sbjct: 677  ---TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANG-VRDSAPLHVR 732

Query: 1569 QKPV--ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
               V    +S+ D  ++ + GD  ++   +   P  +V W+K+G +L    + NI ++ K
Sbjct: 733  PVEVKFSPLSDTDGNKRVETGDAIVLYCEVSH-PFAQVSWFKDGKELLMTDDLNIQSEGK 791

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
               + I+    SH+  YT E S      +VEV     +    PE  +    +  + V + 
Sbjct: 792  MRRVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLL 851

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDN 1710
                 +D  +   K   E H  +N
Sbjct: 852  CHVSAEDAEVTWYKDGCEIHPSEN 875



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 84/363 (23%), Positives = 132/363 (36%), Gaps = 17/363 (4%)

Query: 462 LTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK 519
           LT+E      + LM+E  N Y+        E+ + L +            P F+ K    
Sbjct: 102 LTQEVRQPEVKELMEEPGNGYSALQNGACGEE-NGLSLNGDANDTSSDDKPRFLIKPLSL 160

Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPE 576
               G    F C++ G P P++ W +    +     S  F +   D     L I      
Sbjct: 161 RVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISEQDGGWFQLRIYRTRMP 220

Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI-PPT 635
           D G +TC A N  G A +   L+VEA      S M+                   + PP 
Sbjct: 221 DKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTSRLLPKHRSHKAALEPPV 280

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
              K K   V EG      C +   P+P+I W  K + +  +      I  D   Y + L
Sbjct: 281 DVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVW--KKDGVPLEAGRRHLIFEDREGYYT-L 337

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
           K+   K+   G Y   A N  G     + L +K       +   PLK + VR+ +  +L 
Sbjct: 338 KVLYCKEKDTGLYVCAASNALGNTLSAVHLSVK---GSAGKFRRPLKDVEVRERDVAVLE 394

Query: 756 AQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEG 812
             V     P   + ++ +  P      +  G    +TI +     D+GVY  +  + ++ 
Sbjct: 395 CDVPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTI-RDVAADDDGVYLCEIPDGAKS 453

Query: 813 IAE 815
           IAE
Sbjct: 454 IAE 456



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP  +   RP     GS     C ++G PRP + W R+   I     + +  ++     L
Sbjct: 7   APRVLGYPRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRY-VLSEEGKAYLL 65

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            I  V  +DAG + C AKN+ G   +   L VE
Sbjct: 66  AIAGVTAQDAGQYICKAKNSIGETYAAASLKVE 98



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 8/155 (5%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            + G +  +  +I+G P P+VIW +   ++ +   Y ++ + K  ++ I  +    + +Y 
Sbjct: 20   RCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEGKAYLLAIAGVTAQDAGQYI 79

Query: 1645 IEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
             +A N+ G +    +LKV       +  +PE   +M E       ++     ++ GL L 
Sbjct: 80   CKAKNSIGETYAAASLKVEGEALTQEVRQPEVKELMEEPGNGYSALQNGACGEENGLSLN 139

Query: 1700 KYAIEKHEPDNNRW-IKVAD--VDRDVETYCIQKL 1731
              A +    D  R+ IK     VDR  + Y   KL
Sbjct: 140  GDANDTSSDDKPRFLIKPLSLRVDRGEDAYFSCKL 174



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 35/124 (28%), Positives = 50/124 (40%), Gaps = 7/124 (5%)

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
           DI  G P      P+      GSD  L C +   P PD+ W  K  +IV      ++ E 
Sbjct: 2   DIFGGAPRVLGY-PRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEG 60

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMI 745
             ++    L I  V     G Y   A N  GE      LK++ GE    +V +P +K ++
Sbjct: 61  KAYL----LAIAGVTAQDAGQYICKAKNSIGETYAAASLKVE-GEALTQEVRQPEVKELM 115

Query: 746 VRQG 749
              G
Sbjct: 116 EEPG 119



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 859 NPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
           +P P + W R N +I+S    +    +G+   L I  V ++ D+G Y C A NS G++  
Sbjct: 34  DPRPDVIWERKNVQIVSGGRYVLSE-EGKAYLLAIAGVTAQ-DAGQYICKAKNSIGETYA 91

Query: 918 GARVTIDVEKVT 929
            A + ++ E +T
Sbjct: 92  AASLKVEGEALT 103



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
           P+V+   + ++ R G    L   + G+PRP + W + N  + +        +G  + + I
Sbjct: 8   PRVLGYPRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEGKAYLLAI 67

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAEP 832
                 +D G Y  KA+NS G    +A + VE    T+E  +P
Sbjct: 68  -AGVTAQDAGQYICKAKNSIGETYAAASLKVEGEALTQEVRQP 109



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 6/99 (6%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E + +    V+ LR +   +   V  EC V    R   TW++    + PS   ++  DD 
Sbjct: 1826 EVEELPVSIVKPLRDRTALEKHRVILECTVSS-ARCCATWYKDGKEVVPSDRVEIL-DDG 1883

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
                LVI+EV  ED GT++       G  +S  +L+VEA
Sbjct: 1884 CSLKLVIQEVAVEDEGTYSV----EVGEHTSKAKLMVEA 1918


>UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n=2;
            Bos taurus|Rep: UPI0000F34A69 UniRef100 entry - Bos
            Taurus
          Length = 4164

 Score =  148 bits (359), Expect = 1e-33
 Identities = 242/1155 (20%), Positives = 432/1155 (37%), Gaps = 112/1155 (9%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            GS +   C V G P P +TW +    ++ S    +         L +  + P+ AGT+TC
Sbjct: 3003 GSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVV---SRGGRLQLSHLQPDQAGTYTC 3059

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            VA+NA   A +  + +V          + V              +LEG            
Sbjct: 3060 VAENAQ--AEAHKDFVV---------AVLVAPRIQSSGTTQEHSVLEG------------ 3096

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
                  D+ L+C +   P P + WL  G  +  DE++   +    ++  S L + +++  
Sbjct: 3097 -----QDVQLDCEVDGQPPPYVVWLKDGSPL--DESVGPYLW--FYLNGSSLVLKDLRAS 3147

Query: 704  QEGTYTVVAVNREGE-ASLPI--VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
              G YT VA N  GE A L    VL   T E+ P    E   +++ R G+ V ++  V G
Sbjct: 3148 DSGAYTCVARNAAGEDAKLYTVNVLVPPTIEQGP----EGAGTLVHRLGDLVSMACPVRG 3203

Query: 761  NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
            +P   ++W K+  P   LP       HS       ++ D G +T  A +  G+A    ++
Sbjct: 3204 SPPIHVSWLKDGLP---LPLSHRTHLHSSGRTLRVQLADSGTFTCVAASPAGVANRHFIL 3260

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
             V  P     EP  F N   ++ V     + L      +P+P ++W ++ E + P     
Sbjct: 3261 QVLVPPV--LEPAEFQN---DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLPQS--L 3313

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
            ++  G  +E           +G Y CVA + AG++    ++T+            +    
Sbjct: 3314 EHGPGLLLEAAEAG-----HAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLL 3368

Query: 941  EEGKTVILECQT--SHTVSTKWYHNKKEIS----GMDHREIIQ-EGRXXXXXXXXX--XX 991
              G  + L C    + T +  W+ + + +S    G   R +++ EG              
Sbjct: 3369 TPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQGARRVLRVEGVQVSDAGLYTCLAH 3428

Query: 992  XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWE 1050
               G ++   + +  +   V+    P F+  L   ++      +LE  + ++ A ++ W 
Sbjct: 3429 SPAGEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQL------VLECSVEADPAPEIEWH 3482

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPP 1107
            R+G +++   +   F + G  R L ++  S  D G+YSC   + + +  +     V  PP
Sbjct: 3483 REGVLLQADAHT-QFPEEG--RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPP 3539

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ-FSNHIQLTIDGKKQKLKIY 1166
             +     N  VN+      + +      LV W KDG  +   S    L  +G ++ L+I 
Sbjct: 3540 TV-----NASVNQTTLLPCQADGVP-QPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQ 3593

Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222
                +DAG Y C      G+ +    L V EP        P  + + A T A L  E   
Sbjct: 3594 PVLAEDAGHYLCLASNPAGSDRQGRDLQVFEPPA--IAPGPSNLTLTAYTPASLPCEASG 3651

Query: 1223 ETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLK 1280
                 V W+K    ++   +      +    L++ + +  D   + CV+ +      KL 
Sbjct: 3652 SPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLY 3711

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSID 1339
               V  PP I D + ++     + V L       P P   W    +++  +    +    
Sbjct: 3712 WVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRV--- 3768

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
            S S +L I +      G Y     N  G A   + +T+   P     P+++   +    +
Sbjct: 3769 SPSGALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVL 3828

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
               E       +I +                + +   Q  I ++    +  +   A N  
Sbjct: 3829 LPCEASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQN-- 3886

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
                A       +++ +     P ++  L +++        L C   G P+PKVTW +DG
Sbjct: 3887 ---SAGSAVRKTRLVVQV---PPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDG 3940

Query: 1520 KKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
            + +  AK   T +                 Y C A N  G       + I   PV T   
Sbjct: 3941 QPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILALPVFTTLP 4000

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637
             D  +  ++GD+  +     G P P++ W  N N+L    E  ++ ++  S ++   + R
Sbjct: 4001 GD--RSLRLGDKLWLHCAARGSPTPQIGWTVN-NRLVTATE-GVSEQDGGSTLQRVAVTR 4056

Query: 1638 SHSSKYTIEASNTAG 1652
              S  Y   A N  G
Sbjct: 4057 EDSGTYVCWAENRVG 4071



 Score =  147 bits (356), Expect = 3e-33
 Identities = 229/1067 (21%), Positives = 417/1067 (39%), Gaps = 94/1067 (8%)

Query: 649  SDILLECRLVAIPEPDIAWLFKGEE-IVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            S + L C    IP P I W F+GEE + P EN  +     +  +  +LK+T  ++   G 
Sbjct: 2245 SPLSLFCEATGIPPPGIRW-FRGEEPVSPGENTYLLAGKKISGW--MLKLTRAQEQDRGL 2301

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y+ +A N  GEA     +++            P+    +R       S    G+P+P +T
Sbjct: 2302 YSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPSSLRASG----SGPSTGHPQPKVT 2357

Query: 768  WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV-EEPT 826
            W K+ +P+ +          ++  +    +   G Y   A N+ G       ++V   PT
Sbjct: 2358 WFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHFQLSVLVVPT 2417

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                      +  +E+TV     I L+      P P+ITW ++         I Q   G 
Sbjct: 2418 ILGVTED---SMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALNNI-QLLPGT 2473

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-----EKVTFVKHLQKSYETE 941
            +  L I N   E D+G Y CV +N  G++     V + +     +   F +   K  +T+
Sbjct: 2474 H-GLQILNAQKE-DAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKEVKTK 2531

Query: 942  EGKTVILECQT--SHTVSTKWYHN-----KKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
               T+ LEC++      +  WY +     +K ++      I+ EGR            D 
Sbjct: 2532 VNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGR--LLQIQPTQVSDS 2589

Query: 995  GVIKCIV------KDQETSTMLVVKETI---PEFIRKLQDF-EVKEKDVAILEVEINS-E 1043
            G   C+        DQ+ + ++   ET     E    + ++ E+ E + A L  + N+  
Sbjct: 2590 GRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVP 2649

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEV 1100
             A++ W R G+  +P   +         R L I      D G YSC   +   E      
Sbjct: 2650 AAELTWYR-GD--RPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYE 2706

Query: 1101 TVVELPPEIITR----LQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLT 1155
             +V  PP I+      ++   VN  +  +    +    A  + W ++G     S  +Q+ 
Sbjct: 2707 LLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVL 2766

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPA 1210
             +G+   L++   ++ DA  Y C      G+++    L V+ EP +N     PE I    
Sbjct: 2767 ENGR--ILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLN-----PEQITATL 2819

Query: 1211 NTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
            N+   L  ++    + +VTWYK    +   E+  L+      TL + +    D   Y C 
Sbjct: 2820 NSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLLPGT--HTLQLTRVQLLDSGMYICE 2877

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
             L+A       V++    P      ++   +  G    L  +  AFP+P   W  + + +
Sbjct: 2878 ALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPL 2937

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGK 1386
               +  +  +  +   L I+  + +D G+Y  R+ N  G A    ++T+   P+   P  
Sbjct: 2938 VLPERIQALLGGQ--RLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPPTFENPET 2995

Query: 1387 PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
              +  +  S + +  D    TG  +  + ++ +   ++++    V +    +  + +L+ 
Sbjct: 2996 EMVSRVAGSPLVLSCDV---TGVPAPAVTWLKDRMPVESSMARGVVS-RGGRLQLSHLQP 3051

Query: 1446 NSSYRFRAYAVNEVDISDASETTEY-YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
            + +  +   A N    + A    ++   V+   +IQS    +  ++   E  +D++L C 
Sbjct: 3052 DQAGTYTCVAEN----AQAEAHKDFVVAVLVAPRIQSSGTTQ--EHSVLE-GQDVQLDCE 3104

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P P V W +DG  L  +       Y N                Y C+A N  GE  
Sbjct: 3105 VDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGEDA 3164

Query: 1561 TSCVVGIQQKPVITISNEDI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                V +   P I    E      H++GD   +   + G PP  V W K+G  L      
Sbjct: 3165 KLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRT 3224

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            ++ +  +T  +++ +     S  +T  A++ AG ++    L+V   P
Sbjct: 3225 HLHSSGRTLRVQLAD-----SGTFTCVAASPAGVANRHFILQVLVPP 3266



 Score =  141 bits (342), Expect = 2e-31
 Identities = 233/1076 (21%), Positives = 401/1076 (37%), Gaps = 100/1076 (9%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P   S+      V  G   +L C   A PEP +AW   G+ +V  E I   +        
Sbjct: 2896 PGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQR---- 2951

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGES 751
              L+I + +   +G Y+    N  GEA     L ++     PP    P   M+ R  G  
Sbjct: 2952 --LEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQV----PPTFENPETEMVSRVAGSP 3005

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAE 808
            ++LS  V G P P +TW K+  PV++   +   S G    ++ L+P +    G YT  AE
Sbjct: 3006 LVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGGRLQLSHLQPDQA---GTYTCVAE 3062

Query: 809  NSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            N++  A    V+ V   P  +++         QE +V E   ++L   V   P P + W 
Sbjct: 3063 NAQAEAHKDFVVAVLVAPRIQSS------GTTQEHSVLEGQDVQLDCEVDGQPPPYVVWL 3116

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            ++   +  S      F      LV+ ++ +  DSG Y CVA N+AG+ +     T++V  
Sbjct: 3117 KDGSPLDESVGPYLWFYLNGSSLVLKDLRAS-DSGAYTCVARNAAGEDA--KLYTVNVLV 3173

Query: 928  VTFVKHLQKSYET---EEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
               ++   +   T     G  V + C  + S  +   W  +   +       +   GR  
Sbjct: 3174 PPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRTHLHSSGR-- 3231

Query: 983  XXXXXXXXXXDVGVIKCIVKDQE--TSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILE 1037
                      D G   C+        +   +++  +P  +   +   D  V    +  L 
Sbjct: 3232 ---TLRVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQNDVAVVRGSLVFLP 3288

Query: 1038 VEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             E   S    V W +DGE + P+  +       H   L +        G YSC+   E+ 
Sbjct: 3289 CEARGSPLPFVSWVKDGEPLLPQSLE-------HGPGLLLEAAEAGHAGTYSCVAVSEAG 3341

Query: 1097 TA----EVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDGSEIQFS 1149
             A    ++TV++ PP I    Q +++        E+    +G     + W KDG  + + 
Sbjct: 3342 EARRHFQLTVMD-PPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWP 3400

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEF 1205
               Q    G ++ L++    + DAG Y+C      G  + +  + V+ P        P F
Sbjct: 3401 EDGQ----GARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRVQAPPNVIGSHGPRF 3456

Query: 1206 I--LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
            +  L P       +VE  D   ++ W+ ++ V+   +  T   + + R L ++  +  D 
Sbjct: 3457 VVGLAPGQLVLECSVE-ADPAPEIEWH-REGVLLQADAHTQFPE-EGRFLQLQALSTADS 3513

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA--FPQPNDEW 1321
             +Y+C   +A  +T L           V+  R   +    + T L+  QA   PQP   W
Sbjct: 3514 GDYSCTAHNAAGSTSLAFH--------VEVHRPPTVNASVNQTTLLPCQADGVPQPLVSW 3565

Query: 1322 IVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            + +   +         + +     L I+ V   DAG Y     N  G      ++ + + 
Sbjct: 3566 LKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVFEP 3625

Query: 1381 PS-PPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEID-TTEWISVKNITKTQ 1437
            P+  PG  N+     +  ++     E +G+   ++ +  + Q++D   +  + + +    
Sbjct: 3626 PAIAPGPSNLTLTAYTPASL---PCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNA 3682

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
              ++      S  F     N V      E  + Y V   T    P +     + T     
Sbjct: 3683 LLLEEPSPQDSALFECVVSNGV-----GEARKLYWV---TVHVPPAIADDQTDFTATIMA 3734

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFND 1555
             + LTC   GVP P V+W + G +L      Y                    Y C A N 
Sbjct: 3735 PVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPSGALEIGQALPIHTGRYTCAARNA 3794

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             G      V+ +Q  PV+      +    K  +E L+     GIP P + W K G  +  
Sbjct: 3795 AGMAHKHVVLTVQASPVVKPLPSVVWAVAK--EEVLLPCEASGIPRPSIAWQKEGLSVPA 3852

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
                  T       +RI  +    +  Y   A N+AG++  +  L V   P+   G
Sbjct: 3853 ANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTG 3908



 Score =  141 bits (341), Expect = 2e-31
 Identities = 212/1070 (19%), Positives = 393/1070 (36%), Gaps = 94/1070 (8%)

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
            S + L C + A P P++ W   G  +   E I +      H     L++T V+    G Y
Sbjct: 2821 SSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLL--PGTH----TLQLTRVQLLDSGMY 2874

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
               A+N  G     + L +      P     P   ++V  G+  +LS +    P PT+ W
Sbjct: 2875 ICEALNAAGRDHKLVQLSVLA----PGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAW 2930

Query: 769  CKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
             K+ +P+  LP +         + ++  +V D+G+Y+ +  N+ G A  +  +TV+ P  
Sbjct: 2931 QKDGQPL-VLPERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVP-- 2987

Query: 828  ENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                 P F N   E+  +  G+ + L   VT  P P++TW ++   +  S        G 
Sbjct: 2988 -----PTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGG 3042

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
             ++L     D    +G Y CVA N+  ++     V + V          + +   EG+ V
Sbjct: 3043 RLQLSHLQPDQ---AGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDV 3099

Query: 947  ILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
             L+C+          W  +   +       +                 D G   C+ ++ 
Sbjct: 3100 QLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNA 3159

Query: 1005 --ETSTMLVVKETIPEFIRKLQD----FEVKEKDVAILEVEIN-SETADVVWERDGEIIK 1057
              E + +  V   +P  I +  +       +  D+  +   +  S    V W +DG +  
Sbjct: 3160 AGEDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDG-LPL 3218

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEII-TRL 1113
            P  ++      G   ++ +      D G ++C+    +  A    +  V +PP +     
Sbjct: 3219 PLSHRTHLHSSGRTLRVQLA-----DSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEF 3273

Query: 1114 QNQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
            QN   V +G+      E  +G  L  V W KDG  +     +  +++     L +   + 
Sbjct: 3274 QNDVAVVRGSLVFLPCE-ARGSPLPFVSWVKDGEPL-----LPQSLE-HGPGLLLEAAEA 3326

Query: 1171 DDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TL 1225
              AG YSC    E G ++    LTV +P        PE +L+   T   L  +     T 
Sbjct: 3327 GHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTP 3386

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            ++TW+K    +   E         +R L +      D   YTC+        +    + V
Sbjct: 3387 NITWHKDGRALSWPED----GQGARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRV 3442

Query: 1285 EFPPKIV-DYEREYRIKRG-SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            + PP ++  +   + +      + L    +A P P  EW     +++   HT+     + 
Sbjct: 3443 QAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHREGVLLQADAHTQ--FPEEG 3500

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L ++ +   D+G Y     N  G   +  +V +   P+     N      +++  C  
Sbjct: 3501 RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVN-----QTTLLPCQA 3555

Query: 1403 EPENTGNSTIIYYVVEYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
            +        ++ ++ +   +D  +T W+  +   +    IQ +    +  +   A N   
Sbjct: 3556 DGVP---QPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAG 3612

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
                    + +        + P +     N+T        L C   G P+P V W++DG+
Sbjct: 3613 SDRQGRDLQVF--------EPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQ 3664

Query: 1521 KL--KTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            KL  +  +  Y                    ++C+  N  GE      V +   P I   
Sbjct: 3665 KLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPAIADD 3724

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKEL 1635
              D      +    ++T    G+P P V W K G +L      Y ++    +  + I + 
Sbjct: 3725 QTDFTA--TIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVS---PSGALEIGQA 3779

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
               H+ +YT  A N AG +   V L V   P     P ++  +++E V +
Sbjct: 3780 LPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLL 3829



 Score =  138 bits (335), Expect = 1e-30
 Identities = 214/993 (21%), Positives = 388/993 (39%), Gaps = 91/993 (9%)

Query: 734  PPQVIE---PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHS 788
            PP++I    PL ++       + L  +  G P P I W +  +PV          G   S
Sbjct: 2226 PPELIGDLGPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKIS 2285

Query: 789  ITILKPKKV--KDEGVYTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITV 844
              +LK  +   +D G+Y+  A N  G A  + S  +    P   +  PP+  +     ++
Sbjct: 2286 GWMLKLTRAQEQDRGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPS-----SL 2340

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
            +  G+       T +P P +TW+++ + ++  +    + DG  + ++  N+ S   +G Y
Sbjct: 2341 RASGS----GPSTGHPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSS---AGHY 2393

Query: 905  KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV------ILECQTSHTVST 958
             CVA+N+ G+ +   ++++ V   T +   + S + E   T+      I E +   T + 
Sbjct: 2394 ACVAANAIGEKTKHFQLSVLVVP-TILGVTEDSMDEEVTVTINNPISLICETRAFPTPTI 2452

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI 1016
             W  +      +++ +++                D G   C+V ++  E      V+  I
Sbjct: 2453 TWMKDGVPFEALNNIQLLP--GTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLI 2510

Query: 1017 PEFIRKLQDF------EVKEKDVAILEVEINS---ETADVVWERDGEII--KPKKNKYDF 1065
            P  I K   F      EVK K  + L +E  S       + W +DG+ +  KP       
Sbjct: 2511 PPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRV 2570

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILR------DESCTAEVTVVELP---PEIITRL-QN 1115
               G  R L I+ T V D G Y C+        D+     +   E P    E    + + 
Sbjct: 2571 RILGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEY 2630

Query: 1116 QKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
            +++ + N A    +     A  + W++    +   + + +   G+  ++ +     +DAG
Sbjct: 2631 REIVENNPAYLYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRA--EDAG 2688

Query: 1175 EYSC----EVGNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEI-PDETLDV 1227
             YSC    EVG       L V  P +    T  L E + V AN+   L   +  +    +
Sbjct: 2689 RYSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTI 2748

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEF 1286
            +W +       + +  ++ +   R L +      D   Y CV  + A ST KL    V+ 
Sbjct: 2749 SWLQNGLPFSPSPRLQVLEN--GRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQG 2806

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             P +     +      S V+L  D +A P P   W  +   +   +     +   + +L 
Sbjct: 2807 EPGL--NPEQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEI--FLLPGTHTLQ 2862

Query: 1347 IKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            + +V+  D+G+Y     N  G  H  V+++V     PS P    ++     ++  C  E 
Sbjct: 2863 LTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSC--ET 2920

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
            +     T+ +   + Q +   E I    +   +  IQ+ + +    +     N      A
Sbjct: 2921 DAFPEPTVAWQ-KDGQPLVLPERIQAL-LGGQRLEIQDAQVSDKGLYSCRVSNA-----A 2973

Query: 1465 SETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
             E    + +  +     PT E P  + ++      + L+C   GVP P VTW +D   ++
Sbjct: 2974 GEAMRAFSLTVQV---PPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVE 3030

Query: 1524 T--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
            +  A+                     Y C+A N   E     VV +   P   I +    
Sbjct: 3031 SSMARGVVSRGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAP--RIQSSGTT 3088

Query: 1582 QKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639
            Q+H V  G +  +   ++G PPP V+W K+G+ L+      +      S + +K+L+ S 
Sbjct: 3089 QEHSVLEGQDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASD 3148

Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            S  YT  A N AG  +   T+ V   P+  +GP
Sbjct: 3149 SGAYTCVARNAAGEDAKLYTVNVLVPPTIEQGP 3181



 Score =  136 bits (330), Expect = 5e-30
 Identities = 259/1231 (21%), Positives = 441/1231 (35%), Gaps = 117/1231 (9%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVE-KLRPKHTPDGSTVQFECQVE 534
            D   YT  +  +L E +    V E       S   +F E  ++   T   ST+  EC+  
Sbjct: 2485 DAGQYTCVVTNELGEAMKNYHV-EVLIPPSISKDDLFGEVSMKEVKTKVNSTLTLECESW 2543

Query: 535  GYPRPQITWFR--QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
              P P I+W++  Q    KP    Q          L I+     D+G + CVA N AG  
Sbjct: 2544 AVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSGRYLCVATNVAGED 2603

Query: 593  SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652
                 ++++        E                +I+E         P   Y D      
Sbjct: 2604 DQDFNVLIQ------DFETPFWGEEARGGVTEYREIVE-------NNPAYLYCDTN---- 2646

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
                  A+P  ++ W ++G     D  +S+     +     VL+I  V+    G Y+  A
Sbjct: 2647 ------AVPAAELTW-YRG-----DRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKA 2694

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             N  GE  L   L + T      +  E ++ + V    +V L   V+GNP PTI+W +N 
Sbjct: 2695 SNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNG 2754

Query: 773  KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832
             P    P     +   I  +   +V D   Y   AEN  G   T  + T+    E    P
Sbjct: 2755 LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAG--STEKLFTLRVQGEPGLNP 2812

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
                   ++IT     ++ L   V  +P P +TWY++   +S  E I     G +  L +
Sbjct: 2813 -------EQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFL-LPGTH-TLQL 2863

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
            T V   +DSG Y C A N+AG+      V + V         Q       G   +L C+T
Sbjct: 2864 TRVQL-LDSGMYICEALNAAGRDH--KLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCET 2920

Query: 953  S--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML 1010
                  +  W  + + +   +  + +  G+            D G+  C V +     M 
Sbjct: 2921 DAFPEPTVAWQKDGQPLVLPERIQALLGGQ--RLEIQDAQVSDKGLYSCRVSNAAGEAMR 2978

Query: 1011 VVKETI---PEFIRKLQDFEVK-EKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDF 1065
                T+   P F     +   +      +L  ++    A  V W +D   ++    +   
Sbjct: 2979 AFSLTVQVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVV 3038

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIIT--RLQNQKVNK 1120
             + G   +L + +      G Y+C+  +    A    V  V + P I +    Q   V +
Sbjct: 3039 SRGG---RLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLE 3095

Query: 1121 GNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
            G     + E+  +    V W KDGS +  S    L        L + D    D+G Y+C 
Sbjct: 3096 GQDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCV 3155

Query: 1180 VGN-----SKCTAILTVEEPSINFTLRLPE--FILVPANTDAYLTVEIP---DETLDVTW 1229
              N     +K   +  +  P+I    + PE    LV    D  +++  P      + V+W
Sbjct: 3156 ARNAAGEDAKLYTVNVLVPPTIE---QGPEGAGTLVHRLGD-LVSMACPVRGSPPIHVSW 3211

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPP 1288
             K    +  + +  L S    RTL ++     D   +TCV    A    +  +  V  PP
Sbjct: 3212 LKDGLPLPLSHRTHLHS--SGRTLRVQLA---DSGTFTCVAASPAGVANRHFILQVLVPP 3266

Query: 1289 KI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             +   +++ +  + RGS V L  + +  P P   W      +K  +   P        L 
Sbjct: 3267 VLEPAEFQNDVAVVRGSLVFLPCEARGSPLPFVSW------VKDGEPLLPQSLEHGPGLL 3320

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINICWDEP 1404
            ++  E   AG Y     +  G A     +T++D P      +P  L +   +      + 
Sbjct: 3321 LEAAEAGHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDA 3380

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
              T    I +    +++     W       +    ++ ++ + +  +   A      S A
Sbjct: 3381 RGTPTPNITW----HKDGRALSWPEDGQGARRVLRVEGVQVSDAGLYTCLA-----HSPA 3431

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
             E  + +++  +          P   +   P + + L C     P P++ W+R+G  L+ 
Sbjct: 3432 GEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQ-LVLECSVEADPAPEIEWHREGVLLQA 3490

Query: 1525 AKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582
               T   E                 Y C A N  G    +  V + + P +  S      
Sbjct: 3491 DAHTQFPEEGRFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNAS------ 3544

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSS 1641
               V    L+    +G+P P V W K+G  L+      +  +E     +RI+ +    + 
Sbjct: 3545 ---VNQTTLLPCQADGVPQPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAG 3601

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             Y   ASN AG+      L+V++ P+   GP
Sbjct: 3602 HYLCLASNPAGSDRQGRDLQVFEPPAIAPGP 3632



 Score =  130 bits (315), Expect = 3e-28
 Identities = 245/1116 (21%), Positives = 418/1116 (37%), Gaps = 135/1116 (12%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIV--PDENISVAIESDMH 689
            PP+ S         +G + +LEC    +P P + W ++G+ E++  P+++IS        
Sbjct: 668  PPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIW-YRGDLEMILAPEDSIS-------- 718

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                +L+I  V++   G YT  AVN  G+AS  I L++       PQ++E  + + V  G
Sbjct: 719  ---GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVG----HAPQLLELPQDVTVELG 771

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKAL-----PTKSDGDTHSITILKPKKVKDEGVYT 804
             S +L+ +  G+P PTITW + +     L       ++DG  H    L    ++D G Y+
Sbjct: 772  RSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADGSLH----LDQALLEDAGRYS 827

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
                N+ G       + V+       +P         IT  E     L    +  P P+I
Sbjct: 828  CVVSNTAGSHHRDVQLVVQVKVPPRIQP----TATHHIT-NEGVPASLPCVASGVPTPTI 882

Query: 865  TWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            TW +  N + S       + DG    LVI     + D+G Y C A+N+ G SS   R+++
Sbjct: 883  TWTKETNALASRDPHYNVSKDGT---LVIPRPSVQ-DAGAYVCTATNAVGFSSQEMRLSV 938

Query: 924  DVEKVTFV--KH---------LQKSYETEE--------GKTVILEC--QTSHTVSTKWYH 962
            ++E    +  KH         +  S+E ++        G  V L+C  Q S      W  
Sbjct: 939  NMEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTK 998

Query: 963  NKKEISGM-DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST--MLVVKETIPEF 1019
            + + +  + D   ++  G             D G+ +C   +   S     +++  +P  
Sbjct: 999  DSRHMLPITDRHHLLPPG---SLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQ 1055

Query: 1020 IRK-LQDFEVKEKDVAILE-VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            ++   +  +V   +   L  V   S    V W +DG  ++ +         G    ++  
Sbjct: 1056 VQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE---------GPEGSVHFA 1106

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVEL------PPEIIT--RLQNQKVNKGNKATFEIE 1129
                   G Y C   + S +A V   EL      PP +    R  N     G   T E +
Sbjct: 1107 AIQTSHAGTYRC---EASSSAGVDAWELDLRVLVPPSLREDGRRANVSGMAGQSLTLECD 1163

Query: 1130 LTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA- 1187
                 A  + W K+G +I      +L +DG +  L        D+G YSC   N   TA 
Sbjct: 1164 ANGFPAPEITWLKNGRQIPAVGSHRL-LDGAR-ALHFPRIQEGDSGLYSCRAENQAGTAQ 1221

Query: 1188 ----ILTVEEPSINFTLRLPEFI-LVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEK 1241
                +L +  PS+       E + L  A  +    T+ +P  T  V W K    +   E 
Sbjct: 1222 RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVP--TPQVEWTKDGQPVFLGEP 1279

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI--VDYEREYR 1298
               + +   + L I      D+  Y CV    A   TK     +  PP I   +   E  
Sbjct: 1280 RVQLQE-DGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEVA 1338

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +  G  V  L + +  P P+  W  +   +     T+         L +++ + +DAG Y
Sbjct: 1339 VMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQLERAQGSDAGTY 1396

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGK---PNILEIDSSSINICWDEPENTGNSTIIYY 1415
              +  N  G  +    + +   P+  G    P +++  +                T+ +Y
Sbjct: 1397 SCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVARGYPPPTVSWY 1456

Query: 1416 VVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
                  +D    W+          S+++L   S   +   A      S A E   +Y V 
Sbjct: 1457 HEGLPVVDRNGTWLGAGG---GVLSLESLGEASGGLYSCVA-----SSPAGEAVLHYSVE 1508

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYEN 1531
             +   Q   V + L  +TT   + + L C   G P P + W ++G   ++L     T E 
Sbjct: 1509 VQVAPQL-LVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEG 1567

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEW 1590
                            + C A N+ G       + + + P V+ +  E+I          
Sbjct: 1568 -TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFL--QPV 1624

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
             +     G+P P + W+K+G          +        ++I+++       YT  A+N 
Sbjct: 1625 TLRCAGTGVPTPSLRWWKDG----------VALAASGGSLQIEKVDLKDEGTYTCVATNL 1674

Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            AG S  EV L+V   P+   G V    +   SVT+E
Sbjct: 1675 AGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLE 1710



 Score =  122 bits (294), Expect = 1e-25
 Identities = 213/958 (22%), Positives = 349/958 (36%), Gaps = 77/958 (8%)

Query: 627  DILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
            D+L  IPP+      AQ V    G+   LECR + +P P + W   G+ +   E   V +
Sbjct: 1225 DLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEP-RVQL 1283

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLK 742
            + D      VL+ITN     EG Y  VA +  G+ +    L+I      PP +       
Sbjct: 1284 QEDGQ----VLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHA----PPTIWGSNETS 1335

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800
             + V +G  V    +  G P P ITW K+  P+  +P+     T     L+ ++ +  D 
Sbjct: 1336 EVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQLERAQGSDA 1393

Query: 801  GVYTLKAENSEGIAETSAVITVEEPT--EENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            G Y+ KA N+ G+ E +  + V  P   E   E P    R  +       T++ VAR   
Sbjct: 1394 GTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGP----RVVKAVAGRPLTLECVAR--G 1447

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P+++WY     +           G  + L       E   G Y CVAS+ AG++   
Sbjct: 1448 YPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLG---EASGGLYSCVASSPAGEAVLH 1504

Query: 919  ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VST-KWYHNKKEISGMDHREII 976
              V + V     V        T  G+++ L C  S + V T +W  N      +    + 
Sbjct: 1505 YSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVT 1564

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF----IRKLQDFEVK-EK 1031
             EG               G+  C   ++  +    V+ ++ E     I   ++      +
Sbjct: 1565 SEG--TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQ 1622

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI- 1090
             V +        T  + W +DG  +         EK             + DEG Y+C+ 
Sbjct: 1623 PVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQIEK-----------VDLKDEGTYTCVA 1671

Query: 1091 --LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148
              L  ES    +  V +PP I   L N+ V +    T E  L  G   V       E+  
Sbjct: 1672 TNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLEC-LASG---VPPPGKVWELGL 1727

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
             N            LKI  C +   G     VG       LTV  P  +     P    +
Sbjct: 1728 GNDEPAVWGVLYSLLKI--CLV---GGLLAGVGCEGARLALTVLAPGCSSL--CPSLPSI 1780

Query: 1209 PANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            P+ T A             +++W+K +  I   ++  + +D   R L+I +    D   Y
Sbjct: 1781 PSQTTAIFCSHPSSFQAFSNISWFKGRQPISAWDRAMVSTD--GRVLLIEQAQLSDAGSY 1838

Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
             CV  +   +T+L+  + V  PP I+  E+   +     V L     A P P   W  + 
Sbjct: 1839 RCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVANESVALECRSHAVPPPVLSWRKDG 1898

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPP 1384
            + ++       S D   A L + + E  D G Y     N  G ++   N+ +   P  P 
Sbjct: 1899 RPLEPRPGVYLSAD--KALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNVWVPPVFPS 1956

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
             +P  L +          +         I +  + Q +   E +S+  ++     +  L 
Sbjct: 1957 REPRTLTVTEGHPARLSCDCRGVPFPK-ISWKKDGQPL-PGEGVSLAQVSAVGRLLY-LG 2013

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
                 +   Y     +++  S   +   V    +I  P   +P  +++   +E+  L C 
Sbjct: 2014 RAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPL--EPYADVSVVQDEEASLECN 2071

Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
              G P P+VTW RDG  +  ++      +                Y C+A N+ G  E
Sbjct: 2072 ATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHAGRYSCVAENEAGRAE 2129



 Score =  119 bits (287), Expect = 8e-25
 Identities = 212/1046 (20%), Positives = 383/1046 (36%), Gaps = 82/1046 (7%)

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P+P + W   G+ +   +   V+ +       ++L + +      G Y  VA N  GE +
Sbjct: 2352 PQPKVTWFKDGQPLASGDAHHVSPDG------ALLWVLHANLSSAGHYACVAANAIGEKT 2405

Query: 721  LPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779
                L +           + + + + V     + L  +    P PTITW K+  P +AL 
Sbjct: 2406 KHFQLSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALN 2465

Query: 780  T-KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838
              +    TH + IL  +K +D G YT    N  G A  +  + V  P   + +       
Sbjct: 2466 NIQLLPGTHGLQILNAQK-EDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVS 2524

Query: 839  FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF------DGENIELVI 892
             +E+  K   T+ L       P P+I+WY++ + + P + +T N       +G  +++  
Sbjct: 2525 MKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNL-PEKPVTPNQRVRILGEGRLLQIQP 2583

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-----EGKTVI 947
            T V    DSG Y CVA+N AG+      V I   +  F     +   TE     E     
Sbjct: 2584 TQVS---DSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAY 2640

Query: 948  LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-----I 1000
            L C T+   + +  WY   + +S  D   ++Q GR            D G   C     +
Sbjct: 2641 LYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGR--VLQIPLVRAEDAGRYSCKASNEV 2698

Query: 1001 VKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057
             +D     +LV+   +   E    +++  V       L   +    A  + W ++G    
Sbjct: 2699 GEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFS 2758

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQ 1114
            P       E  G I  L +    V D   Y C+  + + + E      V+  P +     
Sbjct: 2759 PSPRLQVLE-NGRI--LQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLNPEQI 2815

Query: 1115 NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
               +N       ++        V W+KDG  +     I L + G    L++    L D+G
Sbjct: 2816 TATLNSSVSLPCDVRAHPSPE-VTWYKDGWTLSLGEEIFL-LPG-THTLQLTRVQLLDSG 2872

Query: 1175 EYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTW 1229
             Y CE  N+  +   ++ +   +     R  + +LV A   A L+ E    P+ T  V W
Sbjct: 2873 MYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPT--VAW 2930

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288
             K    +   E+   +  +  + L I+     D+  Y+C + +A         + V+ PP
Sbjct: 2931 QKDGQPLVLPERIQAL--LGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPP 2988

Query: 1289 KIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
               + E E   +  GS + L  D    P P   W+ +   ++        + S+   L +
Sbjct: 2989 TFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVE--SSMARGVVSRGGRLQL 3046

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE---IDSSSINICWDEP 1404
              ++   AG Y    EN    A  +  V +L  P         E   ++   + +  D  
Sbjct: 3047 SHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQL--DCE 3104

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
             +      + ++ +   +D +    +   +  +   +++L+ + S  +   A N      
Sbjct: 3105 VDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNA----- 3159

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITT---EPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            A E  + Y V     +  PT+E+  +   T      + + + C   G P   V+W +DG 
Sbjct: 3160 AGEDAKLYTV---NVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGL 3216

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
             L  +  T+ +                + C+A +  G      ++ +   PV+  +    
Sbjct: 3217 PLPLSHRTHLH-SSGRTLRVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQN 3275

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
                  G    +     G P P V W K+G  L         + E    + ++  +  H+
Sbjct: 3276 DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLPQ------SLEHGPGLLLEAAEAGHA 3329

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKP 1666
              Y+  A + AG +     L V D P
Sbjct: 3330 GTYSCVAVSEAGEARRHFQLTVMDPP 3355



 Score =  119 bits (286), Expect = 1e-24
 Identities = 212/1025 (20%), Positives = 380/1025 (37%), Gaps = 104/1025 (10%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI---VPDENISVAIESD 687
            G  P   + P+   V+ G   LL CR    P P I W  +G++    +     S+  +  
Sbjct: 754  GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW-HRGDDQPLGLRGSRHSIRADGS 812

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            +H+  ++L+         G Y+ V  N  G     + L ++   K PP++       I  
Sbjct: 813  LHLDQALLE-------DAGRYSCVVSNTAGSHHRDVQLVVQV--KVPPRIQPTATHHITN 863

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            +G    L     G P PTITW K    + +     +       ++    V+D G Y   A
Sbjct: 864  EGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQDAGAYVCTA 923

Query: 808  ENSEGIAETSAVITVE-EP-------TEENAEPPLFINRFQE------ITVKEKGTIKLV 853
             N+ G +     ++V  EP           A+P + +N   E      +T K    + L 
Sbjct: 924  TNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEVTLD 983

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                 +P P +TW +++  + P           ++ L    V    DSG Y+C ASN AG
Sbjct: 984  CEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVS---DSGLYECTASNPAG 1040

Query: 914  KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973
             ++    + + V     V+   +  +   G+ V L C    +   +   +K  ++     
Sbjct: 1041 SATQYYILRVQVPPQ--VQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVA----- 1093

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFE 1027
             +  EG               G  +C           E    ++V  ++ E  R+     
Sbjct: 1094 -LRGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVLVPPSLREDGRRANVSG 1152

Query: 1028 VKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
            +  + +  LE + N   A ++ W ++G  I P    +        R L+       D G 
Sbjct: 1153 MAGQSLT-LECDANGFPAPEITWLKNGRQI-PAVGSH--RLLDGARALHFPRIQEGDSGL 1208

Query: 1087 YSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWF 1140
            YSC   +++ TA+     +V +PP ++     Q+V     A  E+E  T G     V W 
Sbjct: 1209 YSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWT 1268

Query: 1141 KDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EP 1194
            KDG  +      +QL  DG  Q L+I +  L D G Y C      G       L +   P
Sbjct: 1269 KDGQPVFLGEPRVQLQEDG--QVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPP 1326

Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTL 1253
            +I  +    E  ++  +   +L       T D+TW+K    ++  TE   ++     R L
Sbjct: 1327 TIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTE---VVYTRGGRQL 1383

Query: 1254 IIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             + +    D   Y+C   +A    + TT+L+V V        +  R  +   G  +TL  
Sbjct: 1384 QLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLEC 1443

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
              + +P P   W      +     T   + +    L+++ +     G+Y     +  G A
Sbjct: 1444 VARGYPPPTVSWYHEGLPVVDRNGT--WLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 1501

Query: 1370 DVEMNVTILDKPS---PPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTT 1425
             +  +V +   P      G   +  +   S+ + C+       + + +  +   Q     
Sbjct: 1502 VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCY------ASGSPVPTIQWLQNGHPA 1555

Query: 1426 EWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
            E +   ++T   T+  I +++   +  F   A NE   + A      +++     +    
Sbjct: 1556 EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGG-- 1613

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
                 +NIT    + + L C   GVP P + W++DG  L  +  + +             
Sbjct: 1614 -----ENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQ------IEKVDLK 1662

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                Y C+A N  GE     ++ +   P I   + N+ + +   V  E L +    G+PP
Sbjct: 1663 DEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLAS----GVPP 1718

Query: 1602 PEVIW 1606
            P  +W
Sbjct: 1719 PGKVW 1723



 Score =  119 bits (286), Expect = 1e-24
 Identities = 214/1059 (20%), Positives = 388/1059 (36%), Gaps = 102/1059 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V+  S + L C ++  P P I+WL  G    P   + V +E+       +L+++  +   
Sbjct: 2728 VNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQV-LENG-----RILQVSTAEVAD 2781

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
              +Y  VA N  G       L+++ GE    P Q+   L S       SV L   V  +P
Sbjct: 2782 AASYMCVAENPAGSTEKLFTLRVQ-GEPGLNPEQITATLNS-------SVSLPCDVRAHP 2833

Query: 763  RPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
             P +TW K+   +           TH++ + +  ++ D G+Y  +A N+ G       ++
Sbjct: 2834 SPEVTWYKDGWTLSLGEEIFLLPGTHTLQLTR-VQLLDSGMYICEALNAAGRDHKLVQLS 2892

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNNEIISPSETIT 880
            V  P      P    +R Q++ +   G   +++  T   P P++ W ++ + +   E I 
Sbjct: 2893 VLAP----GAP----SRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQ 2944

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
                G+ +E+    V    D G Y C  SN+AG++     +T+ V   TF     +    
Sbjct: 2945 ALLGGQRLEIQDAQVS---DKGLYSCRVSNAAGEAMRAFSLTVQVPP-TFENPETEMVSR 3000

Query: 941  EEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
              G  ++L C  +     +  W  ++  +     R ++  G               G   
Sbjct: 3001 VAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRG--GRLQLSHLQPDQAGTYT 3058

Query: 999  CIVKD--QETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEINSETAD-VVWERD 1052
            C+ ++   E     VV   +   I+     Q+  V E     L+ E++ +    VVW +D
Sbjct: 3059 CVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQLDCEVDGQPPPYVVWLKD 3118

Query: 1053 GEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPE 1108
            G  +      Y  F   G    L +++    D G Y+C+ R+   E        V +PP 
Sbjct: 3119 GSPLDESVGPYLWFYLNG--SSLVLKDLRASDSGAYTCVARNAAGEDAKLYTVNVLVPPT 3176

Query: 1109 IITRLQNQKV---NKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            I    +         G+  +    +     + V W KDG  +  S+   L   G+  +++
Sbjct: 3177 IEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRTHLHSSGRTLRVQ 3236

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
                 L D+G ++C   +    A    IL V  P +         + V   +  +L  E 
Sbjct: 3237 -----LADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQNDVAVVRGSLVFLPCEA 3291

Query: 1221 PDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
                L  V+W      ++D E     S      L++          Y+CV +      + 
Sbjct: 3292 RGSPLPFVSW------VKDGEPLLPQSLEHGPGLLLEAAEAGHAGTYSCVAVSEAGEARR 3345

Query: 1280 KVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
              ++ V  PP I D ++  E  +  G+ + LL D +  P PN  W  + + +     + P
Sbjct: 3346 HFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRAL-----SWP 3400

Query: 1337 SIDSKSAS--LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
              D + A   L ++ V+ +DAG+Y     +  G  +    + +         PN++    
Sbjct: 3401 E-DGQGARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRV------QAPPNVIGSHG 3453

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
                +            ++   VE       EW     + +     Q  +     + +  
Sbjct: 3454 PRFVV-----GLAPGQLVLECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQ-- 3506

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            A++  D  D S T   +     T +     V +P   +    N+   L C   GVPQP V
Sbjct: 3507 ALSTADSGDYSCTA--HNAAGSTSLAFHVEVHRP-PTVNASVNQTTLLPCQADGVPQPLV 3563

Query: 1514 TWYRDGKKLKTAKATY----EN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            +W +DG  L      +    E  R               Y C+A N  G       + + 
Sbjct: 3564 SWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVF 3623

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
            + P I     ++           +     G P P V W+K+G KL+   +        ++
Sbjct: 3624 EPPAIAPGPSNLTLTAYTPAS--LPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSN 3681

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             + ++E     S+ +    SN  G +     + V+  P+
Sbjct: 3682 ALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA 3720



 Score =  112 bits (270), Expect = 9e-23
 Identities = 198/904 (21%), Positives = 320/904 (35%), Gaps = 81/904 (8%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            T +G      C   G P P ITW ++T  +  S+D   +Y+     TLVI     +DAG 
Sbjct: 862  TNEGVPASLPCVASGVPTPTITWTKETNALA-SRD--PHYNVSKDGTLVIPRPSVQDAGA 918

Query: 581  FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640
            + C A NA GF+S    L V         E                 ++ G     + KP
Sbjct: 919  YVCTATNAVGFSSQEMRLSV-------NMEPGFLLDPKHGATAKPRILVNGSHE--ADKP 969

Query: 641  KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY-CSVLKITN 699
                   G ++ L+C     P P + W      ++P       I    H+     L +  
Sbjct: 970  LRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLP-------ITDRHHLLPPGSLHLAQ 1022

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
             +    G Y   A N  G A+   +L+++     PPQV    + + V  GE+V L+    
Sbjct: 1023 AQVSDSGLYECTASNPAGSATQYYILRVQV----PPQVQPGPRVLKVLVGEAVDLNCVAE 1078

Query: 760  GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            G+P P +TW K+   ++      +G  H   I    +    G Y  +A +S G+      
Sbjct: 1079 GSPEPRVTWSKDGVALRG--EGPEGSVHFAAI----QTSHAGTYRCEASSSAGVDAWELD 1132

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            + V  P     +      R   ++     ++ L       P P ITW +N   I P+   
Sbjct: 1133 LRVLVPPSLRED-----GRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQI-PAVGS 1186

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
             +  DG    L    +  E DSG Y C A N AG +     + + +          +   
Sbjct: 1187 HRLLDGAR-ALHFPRI-QEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVV 1244

Query: 940  TEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
               G    LEC+T    T   +W  + + +   + R  +QE              D G  
Sbjct: 1245 GLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQED-GQVLRITNSHLGDEGWY 1303

Query: 998  KCIV---KDQETSTMLVVKETIPEFIRKLQDFEVKEKD---VAILEVEINSETADVVWER 1051
            +C+      Q+T    +     P      +  EV   +   V  L       T D+ W +
Sbjct: 1304 QCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFK 1363

Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPE 1108
            DG+ + P   +  + + G  R+L +      D G YSC   +     E T    V +PP 
Sbjct: 1364 DGDPLVP-STEVVYTRGG--RQLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPT 1420

Query: 1109 IITRLQNQKVNK---GNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            I    +  +V K   G   T E  + +G     V W+ +G  +   N   L   G    L
Sbjct: 1421 IEGTGEGPRVVKAVAGRPLTLEC-VARGYPPPTVSWYHEGLPVVDRNGTWLGAGG--GVL 1477

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPE---FILVPANTDAYLTVE 1219
             +        G YSC   +    A+L    E  +   L + E    +        YL   
Sbjct: 1478 SLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCY 1537

Query: 1220 IPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
                 +  + W +     E+     + S+    TL I          + C   +   T  
Sbjct: 1538 ASGSPVPTIQWLQNGHPAEELPGVHVTSE--GTTLHIDHVELGHAGLFACQATNEAGTAA 1595

Query: 1279 LKVE--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
             +VE  V E P  ++             VTL       P P+  W  +            
Sbjct: 1596 AEVELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDG----------V 1645

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSS 1395
            ++ +   SL I+KV+  D G Y     N  G +  E+ + +L  P+  PG  N   ++++
Sbjct: 1646 ALAASGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENA 1705

Query: 1396 SINI 1399
            S+ +
Sbjct: 1706 SVTL 1709



 Score =  111 bits (266), Expect = 3e-22
 Identities = 172/783 (21%), Positives = 302/783 (38%), Gaps = 70/783 (8%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C+   +P P ITW +     +   + Q+      +  L  ++   EDAG +TCV  N  G
Sbjct: 2442 CETRAFPTPTITWMKDGVPFEALNNIQLLPGTHGLQILNAQK---EDAGQYTCVVTNELG 2498

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
             A     + V  P S                     D L G       K K       S 
Sbjct: 2499 EAMKNYHVEVLIPPS------------------ISKDDLFGEVSMKEVKTKV-----NST 2535

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            + LEC   A+P P I+W +K  + +P++ ++      +     +L+I   +    G Y  
Sbjct: 2536 LTLECESWAVPPPTISW-YKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSGRYLC 2594

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV-----ILSAQVVGNPRPT 765
            VA N  GE      + I+  + E P   E  +  +    E V      L       P   
Sbjct: 2595 VATNVAGEDDQDFNVLIQ--DFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVPAAE 2652

Query: 766  ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            +TW + ++P+      S      +  +   + +D G Y+ KA N  G       + V  P
Sbjct: 2653 LTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYELLVLTP 2712

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
                 E    +   +E+TV    T+ L   V  NP P+I+W +N    SPS  +    +G
Sbjct: 2713 PVILGETEELV---EEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENG 2769

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
              +++    V    D+  Y CVA N AG +      T+ V+    +   Q +       +
Sbjct: 2770 RILQVSTAEV---ADAASYMCVAENPAGSTE--KLFTLRVQGEPGLNPEQITATLNSSVS 2824

Query: 946  VILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
            +  + +   +    WY +   +S  +  EI                 D G+  C   +  
Sbjct: 2825 LPCDVRAHPSPEVTWYKDGWTLSLGE--EIFLLPGTHTLQLTRVQLLDSGMYICEALNAA 2882

Query: 1006 TSTMLVVKETI--PEFIRKLQDFE-VKEKDVAILEVEINS-ETADVVWERDGE-IIKPKK 1060
                 +V+ ++  P    + QD   V   D A+L  E ++     V W++DG+ ++ P++
Sbjct: 2883 GRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPER 2942

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQK 1117
                 +     ++L I++  V D+G YSC + +   E+  A    V++PP      + + 
Sbjct: 2943 ----IQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPP-TFENPETEM 2997

Query: 1118 VNK--GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
            V++  G+      ++T   A  V W KD   ++ S  +   +  +  +L++     D AG
Sbjct: 2998 VSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESS--MARGVVSRGGRLQLSHLQPDQAG 3055

Query: 1175 EYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VT 1228
             Y+C   N++  A     +  +  P I  +    E  ++    D  L  E+  +    V 
Sbjct: 3056 TYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQ-DVQLDCEVDGQPPPYVV 3114

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP 1287
            W K  S ++++    L   +   +L+++     D   YTCV  +A     KL    V  P
Sbjct: 3115 WLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGEDAKLYTVNVLVP 3174

Query: 1288 PKI 1290
            P I
Sbjct: 3175 PTI 3177



 Score =  109 bits (261), Expect = 1e-21
 Identities = 192/909 (21%), Positives = 344/909 (37%), Gaps = 84/909 (9%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E   AP  +E  +      G +    C+  G+P P ITW R        +  +     D 
Sbjct: 752  EVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADG 811

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              +L + +   EDAG ++CV  N AG      +L+V+  +                    
Sbjct: 812  --SLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVPAS 869

Query: 625  XADILEGIPP---TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
               +  G+P    T++K+  A    +    + +   + IP P +     G  +    N +
Sbjct: 870  LPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQ--DAGAYVCTATN-A 926

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            V   S   M  SV         + G    +   + G  + P +L   + E +     +PL
Sbjct: 927  VGF-SSQEMRLSV-------NMEPG---FLLDPKHGATAKPRILVNGSHEAD-----KPL 970

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
            + +  + G+ V L  +  G+P P +TW K+++ +  +  +          L   +V D G
Sbjct: 971  R-VTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSG 1029

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            +Y   A N  G A    ++ V+ P +    P     R  ++ V E   +  VA    +P 
Sbjct: 1030 LYECTASNPAGSATQYYILRVQVPPQVQPGP-----RVLKVLVGEAVDLNCVAE--GSPE 1082

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            P +TW ++         +    +G    +    + +   +G Y+C AS+SAG  +    +
Sbjct: 1083 PRVTWSKDG--------VALRGEGPEGSVHFAAIQTS-HAGTYRCEASSSAGVDAWELDL 1133

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979
             + V         + +     G+++ LEC  +   + +  W  N ++I  +    ++   
Sbjct: 1134 RVLVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGA 1193

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAIL 1036
            R            D G+  C  ++Q  +        +   P  +      EV     A  
Sbjct: 1194 R--ALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGA 1251

Query: 1037 EVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            E+E   +   T  V W +DG+ +   + +   ++ G +  L I N+ + DEG Y C+   
Sbjct: 1252 ELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV--LRITNSHLGDEGWYQCVAFS 1309

Query: 1094 ES--CTAEVTV-VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI 1146
             +   T +  + +  PP I          V +G+   F  E  +G     + WFKDG  +
Sbjct: 1310 PAGQQTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLCE-ARGVPTPDITWFKDGDPL 1368

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLR 1201
              S  +  T  G+  +L++      DAG YSC+  N+     K T +     P+I  T  
Sbjct: 1369 VPSTEVVYTRGGR--QLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGE 1426

Query: 1202 LPEFILVPANTDAYLTVE-----IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256
             P   +V A     LT+E      P  T  V+WY +   + D     L        L + 
Sbjct: 1427 GPR--VVKAVAGRPLTLECVARGYPPPT--VSWYHEGLPVVDRNGTWL--GAGGGVLSLE 1480

Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR--GSDVTLLVDYQA 1313
               E     Y+CV         L   V V+  P+++  E   ++    G  + L      
Sbjct: 1481 SLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASG 1540

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P P  +W+ N    ++       + S+  +L I  VE   AG++  +  N  G A  E+
Sbjct: 1541 SPVPTIQWLQNGHPAEELPGV--HVTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEV 1598

Query: 1374 NVTILDKPS 1382
             +++ + PS
Sbjct: 1599 ELSVHELPS 1607



 Score =  106 bits (254), Expect = 8e-21
 Identities = 223/1069 (20%), Positives = 387/1069 (36%), Gaps = 95/1069 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP     P+   V  G  + L C     PEP + W   G  +  +       E  +H  
Sbjct: 1052 VPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE-----GPEGSVHFA 1106

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR--QG 749
                    ++    GTY   A +  G  +  + L++      PP + E  +   V    G
Sbjct: 1107 A-------IQTSHAGTYRCEASSSAGVDAWELDLRVLV----PPSLREDGRRANVSGMAG 1155

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            +S+ L     G P P ITW KN + + A+ +    D          +  D G+Y+ +AEN
Sbjct: 1156 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEGDSGLYSCRAEN 1215

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G A+    + V  P        L     QE+        +L  R    P P + W ++
Sbjct: 1216 QAGTAQRDFDLLVLIPPSV-----LGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKD 1270

Query: 870  NEIISPSETITQ-NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             + +   E   Q   DG+ + +  +++    D G Y+CVA + AG+ +   ++ I     
Sbjct: 1271 GQPVFLGEPRVQLQEDGQVLRITNSHLG---DEGWYQCVAFSPAGQQTKDFQLRIHAPPT 1327

Query: 929  TFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
             +  +        EG  V   C+     T    W+ +   +  +   E++          
Sbjct: 1328 IWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQL 1385

Query: 987  XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVA----ILE- 1037
                  D G   C   +     E +T L V   +P  I    +     K VA     LE 
Sbjct: 1386 ERAQGSDAGTYSCKASNAVGVVEKTTRLEVY--VPPTIEGTGEGPRVVKAVAGRPLTLEC 1443

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            V        V W  +G  +  +   +     G +  L + +      G YSC+    +  
Sbjct: 1444 VARGYPPPTVSWYHEGLPVVDRNGTW-LGAGGGV--LSLESLGEASGGLYSCVASSPAGE 1500

Query: 1098 A----EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151
            A     V V   P  ++     Q      ++ +      G  +  ++W ++G   +    
Sbjct: 1501 AVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPG 1560

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
            + +T +G    L I   +L  AG ++C+  N   TA   VE  S++    LP  ++V   
Sbjct: 1561 VHVTSEGTT--LHIDHVELGHAGLFACQATNEAGTAAAEVEL-SVH---ELPSVVIVGGE 1614

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
                  ++        T     S+    +   L +     +L I K    D+  YTCV  
Sbjct: 1615 NITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAAS--GGSLQIEKVDLKDEGTYTCVAT 1672

Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            +    ++ +V + V  PP I        +   + VTL       P P   W +       
Sbjct: 1673 NLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLASGVPPPGKVWELG------ 1726

Query: 1331 CKHTKPSIDSKSASLT-IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
              + +P++     SL  I  V    AG+         G     + +T+L        P++
Sbjct: 1727 LGNDEPAVWGVLYSLLKICLVGGLLAGV---------GCEGARLALTVLAPGCSSLCPSL 1777

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
              I S +  I    P +    + I +    Q I   +   V    +    I+  + + + 
Sbjct: 1778 PSIPSQTTAIFCSHPSSFQAFSNISWFKGRQPISAWDRAMVSTDGRVLL-IEQAQLSDAG 1836

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             +R  A N V       +TE    ++      P++    +N++   NE + L C    VP
Sbjct: 1837 SYRCVASNVVG------STELQYSLRVNA--PPSILGEEQNVSVVANESVALECRSHAVP 1888

Query: 1510 QPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             P ++W +DG+ L+     Y   ++               Y C A N  G  E    + +
Sbjct: 1889 PPVLSWRKDGRPLEPRPGVYLSADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNV 1948

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
               PV   S E        G    ++    G+P P++ W K+G  L  +    ++  + +
Sbjct: 1949 WVPPVFP-SREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGE---GVSLAQVS 2004

Query: 1628 SVIRIKELKRSHSSK---YTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            +V R+  L R+  ++   YT E SN AG SS +  L VY  P +  GP+
Sbjct: 2005 AVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVY-VPPRIAGPL 2052



 Score =  102 bits (244), Expect = 1e-19
 Identities = 158/779 (20%), Positives = 308/779 (39%), Gaps = 72/779 (9%)

Query: 632  IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +PPTF + P+ + V    GS ++L C +  +P P + WL   ++ +P E+   ++   + 
Sbjct: 2986 VPPTF-ENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWL---KDRMPVES---SMARGVV 3038

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L++++++  Q GTYT VA N + EA    V+ +    +   Q     +   V +G
Sbjct: 3039 SRGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRI--QSSGTTQEHSVLEG 3096

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            + V L  +V G P P + W K+  P+     P        S  +LK  +  D G YT  A
Sbjct: 3097 QDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVA 3156

Query: 808  ENSEGI-AETSAVITVEEPT-EENAEPP-LFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             N+ G  A+   V  +  PT E+  E     ++R  ++       + +   V  +P   +
Sbjct: 3157 RNAAGEDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDL-------VSMACPVRGSPPIHV 3209

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            +W ++   +  S     +  G  + + +       DSG + CVA++ AG ++    + + 
Sbjct: 3210 SWLKDGLPLPLSHRTHLHSSGRTLRVQLA------DSGTFTCVAASPAGVANRHFILQVL 3263

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXX 982
            V  V      Q       G  V L C+   S      W  + + +      + ++ G   
Sbjct: 3264 VPPVLEPAEFQNDVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLL----PQSLEHG--P 3317

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKL-QDFEVKEKDVAILEVE 1039
                        G   C+   +        + T+  P +I    Q  E+       LE+ 
Sbjct: 3318 GLLLEAAEAGHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELL 3377

Query: 1040 INSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             ++    T ++ W +DG  +      +  + +G  R L +    V D G Y+C+    + 
Sbjct: 3378 CDARGTPTPNITWHKDGRAL-----SWPEDGQGARRVLRVEGVQVSDAGLYTCLAHSPAG 3432

Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDAL--VRWFKDGSEIQFSN 1150
              E +    V+ PP +I     + V         +E + + D    + W ++G  +Q   
Sbjct: 3433 EVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHREGVLLQADA 3492

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE---EPSINFTLRLPEF 1205
            H Q   +G+   L++      D+G+YSC   N+  +  L   VE    P++N ++   + 
Sbjct: 3493 HTQFPEEGR--FLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVN--QT 3548

Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQC 1264
             L+P   D      +P     V+W K    ++  + ++ L  +  +  L I+    +D  
Sbjct: 3549 TLLPCQADG-----VPQPL--VSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAG 3601

Query: 1265 EYTCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             Y C+  +   + +   ++  F PP I        +   +  +L  +    P+P   W  
Sbjct: 3602 HYLCLASNPAGSDRQGRDLQVFEPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWK 3661

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
            + + +             S +L +++    D+ +++  + N  G A     VT+   P+
Sbjct: 3662 DGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA 3720



 Score =  101 bits (241), Expect = 3e-19
 Identities = 80/320 (25%), Positives = 130/320 (40%), Gaps = 20/320 (6%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P     P   +     ++LL C    IP P IAW  +G   VP  N     +    +   
Sbjct: 3810 PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLS-VPAANPGAGTQV---LPGG 3865

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L+I +V     G Y  +A N  G A    V K +   + PP +   L  + + +G   +
Sbjct: 3866 QLRIIHVSPEDAGNYFCLAQNSAGSA----VRKTRLVVQVPPAIKTGLPDLSITEGAHAL 3921

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L     G+P P +TW K+ +PV     K         ++K  + +D G YT  AEN+ G 
Sbjct: 3922 LPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A     +T+          P+F     + +++    + L      +P P I W  NN ++
Sbjct: 3982 ARRRVHLTI-------LALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLV 4034

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
            + +E +++   G  ++ V    +   DSG Y C A N  G+    A   + V+ V   + 
Sbjct: 4035 TATEGVSEQDGGSTLQRVAVTRE---DSGTYVCWAENRVGRVQ--AVSFVHVKGVPVFQV 4089

Query: 934  LQKSYETEEGKTVILECQTS 953
              +      G +V L CQ S
Sbjct: 4090 KPQDVTVRSGDSVALRCQAS 4109



 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 82/349 (23%), Positives = 142/349 (40%), Gaps = 26/349 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P  S   ++Q   +G ++ + C     P P I+W  +G  +  D  + V  +        
Sbjct: 579 PQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQG------- 631

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            L I  V     G+Y+  A N  G     + L       +PP V      ++  +GE  +
Sbjct: 632 TLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYT----DPPSVSAVNGVVLAAKGEEAV 687

Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
           L  +  G P P + W + +  +   P  S      I +++ +   D GVYT +A N  G 
Sbjct: 688 LECEATGVPPPRVIWYRGDLEMILAPEDSISGMLRIPVVRER---DAGVYTCRAVNELG- 743

Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            + SA I +E         P  +   Q++TV+   +  L  R T +P+P+ITW+R ++  
Sbjct: 744 -DASAEIRLEV-----GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQP 797

Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
                   +   +   L +     E D+G Y CV SN+AG      ++ + V+    ++ 
Sbjct: 798 LGLRGSRHSIRADG-SLHLDQALLE-DAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQP 855

Query: 934 LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-HREIIQEG 979
               + T EG    L C  S   T +  W      ++  D H  + ++G
Sbjct: 856 TATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG 904



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 155/727 (21%), Positives = 279/727 (38%), Gaps = 79/727 (10%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            +I    K +EGTY   AV+R G       + + TG   PPQ++ P+ ++ V  GE+ ILS
Sbjct: 453  EIPRASKAEEGTYECTAVSRAGTGRAKTQIVV-TGP--PPQLV-PVPNVTVSPGETAILS 508

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
              V+      +TW ++ + + A   +          ++     D G Y   A NS G+  
Sbjct: 509  CLVLSEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTR 568

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
             S  + V E  + +        R Q  +  +   +++    +  P P I+W R    +  
Sbjct: 569  ASVWLLVREAPQVSIH-----TRSQRFS--QGMEVRVRCSASGYPAPHISWSREGRALQE 621

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
               +  +  G    L+I  V  E D+G Y C A+N  G+      VT+       V  + 
Sbjct: 622  DSRVRVDAQG---TLIIQGVAPE-DAGSYSCQAANEIGRDEE--TVTLYYTDPPSVSAVN 675

Query: 936  KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
                  +G+  +LEC+ +     +  WY    E+       I                 D
Sbjct: 676  GVVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI-----SGMLRIPVVRERD 730

Query: 994  VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVW 1049
             GV  C   ++       ++  +   P+ +   QD  V+    A+L           + W
Sbjct: 731  AGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW 790

Query: 1050 ER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-----VTVV 1103
             R D + +  + +++     G    L++    + D G YSC++ + + +       V  V
Sbjct: 791  HRGDDQPLGLRGSRHSIRADG---SLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQV 847

Query: 1104 ELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQ 1161
            ++PP I     +   N+G  A+   +        + W K+ + +   + H  ++ DG   
Sbjct: 848  KVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG--- 904

Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI----NFTLRLPEFILVPANT 1212
             L I    + DAG Y C     VG S     L+V  EP               ILV  + 
Sbjct: 905  TLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSH 964

Query: 1213 DA----YLTVEIPDE-TLD----------VTWYK-KKSVIEDTEKFTLISDVKKRTLIIR 1256
            +A     +T +  DE TLD          VTW K  + ++  T++  L+      +L + 
Sbjct: 965  EADKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLL---PPGSLHLA 1021

Query: 1257 KCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
            +    D   Y C   + A S T+  +  V+ PP++    R  ++  G  V L    +  P
Sbjct: 1022 QAQVSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSP 1081

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
            +P   W  +   ++         +    S+    ++ + AG Y+    ++ G    E+++
Sbjct: 1082 EPRVTWSKDGVALRG--------EGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDL 1133

Query: 1376 TILDKPS 1382
             +L  PS
Sbjct: 1134 RVLVPPS 1140



 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 127/570 (22%), Positives = 218/570 (38%), Gaps = 48/570 (8%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTV 1191
            V WFKDG  +   +   ++ DG    L +   +L  AG Y+C   N+     K   +  +
Sbjct: 2356 VTWFKDGQPLASGDAHHVSPDGAL--LWVLHANLSSAGHYACVAANAIGEKTKHFQLSVL 2413

Query: 1192 EEPSINFTLR--LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDV 1248
              P+I       + E + V  N    L  E     T  +TW K     E      L+   
Sbjct: 2414 VVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALNNIQLLPGT 2473

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYE-------REYRI 1299
                L I    ++D  +YTCV+ +   ++     VEV+  PP I   +       +E + 
Sbjct: 2474 --HGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVL-IPPSISKDDLFGEVSMKEVKT 2530

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT---KPSIDSKSASLTIKKVENTDAG 1356
            K  S +TL  +  A P P   W  + + + +   T   +  I  +   L I+  + +D+G
Sbjct: 2531 KVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSG 2590

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSP-------PGKPNILEIDSSSINICWDEPENTGN 1409
             Y     N  G  D + NV I D  +P        G     EI  ++    + +      
Sbjct: 2591 RYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVPA 2650

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + + +Y  + + +   + +SV    +    I  ++   + R+   A NEV      +   
Sbjct: 2651 AELTWYRGD-RPLSIEDGVSVLQGGRV-LQIPLVRAEDAGRYSCKASNEV----GEDWLH 2704

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--A 1527
            Y  ++    +     E+ ++ +T   N  + L C   G P P ++W ++G     +    
Sbjct: 2705 YELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQ 2764

Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
              EN                Y C+A N  G  E    + +Q +P   ++ E I     + 
Sbjct: 2765 VLENGRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEP--GLNPEQITA--TLN 2820

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
                +   +   P PEV WYK+G  L   +E  I     T  +++  ++   S  Y  EA
Sbjct: 2821 SSVSLPCDVRAHPSPEVTWYKDGWTLSLGEE--IFLLPGTHTLQLTRVQLLDSGMYICEA 2878

Query: 1648 SNTAGTSSVEVTLKVY--DKPSKPEGPVIM 1675
             N AG     V L V     PS+P+  V++
Sbjct: 2879 LNAAGRDHKLVQLSVLAPGAPSRPQDVVLV 2908



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 104/492 (21%), Positives = 194/492 (39%), Gaps = 31/492 (6%)

Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DT 1239
            G +K   ++T   P +   + +P   + P  T     + + +   ++TW +   V+   T
Sbjct: 476  GRAKTQIVVTGPPPQL---VPVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSAST 532

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR 1298
             + T ++D+   +L +R  T  D   Y C+  ++   T+  V + V   P++  + R  R
Sbjct: 533  GRVTQLADL---SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQR 589

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
              +G +V +      +P P+  W    + +++    +  +D++  +L I+ V   DAG Y
Sbjct: 590  FSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVR--VDAQG-TLIIQGVAPEDAGSY 646

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
              +  N  G  +  + +   D PS      ++        +   E        +I+Y  +
Sbjct: 647  SCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYRGD 706

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             + I   E  S+  + +    I  ++   +  +   AVNE  + DAS      ++  E  
Sbjct: 707  LEMILAPE-DSISGMLR----IPVVRERDAGVYTCRAVNE--LGDASA-----EIRLEVG 754

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK---LKTAKATYENRXXX 1535
                 +E P +++T E      L C   G P P +TW+R   +   L+ ++ +       
Sbjct: 755  HAPQLLELP-QDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADGSL 813

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                        Y C+  N  G       + +Q K    I           G    +  V
Sbjct: 814  HLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVPASLPCV 873

Query: 1596 IEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
              G+P P + W K  N L   D  YN+ +K+ T VI    ++   +  Y   A+N  G S
Sbjct: 874  ASGVPTPTITWTKETNALASRDPHYNV-SKDGTLVIPRPSVQ--DAGAYVCTATNAVGFS 930

Query: 1655 SVEVTLKVYDKP 1666
            S E+ L V  +P
Sbjct: 931  SQEMRLSVNMEP 942



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 174/894 (19%), Positives = 313/894 (35%), Gaps = 80/894 (8%)

Query: 823  EEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            EE   E   PP  I        +T      + L    T  P P I W+R  E +SP E  
Sbjct: 2217 EETRREYLVPPELIGDLGPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGEN- 2275

Query: 880  TQNFDGENIE---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            T    G+ I    L +T    E D G Y C+ASN AG++     V + +       H + 
Sbjct: 2276 TYLLAGKKISGWMLKLTRA-QEQDRGLYSCLASNEAGEARRDFSVEV-LGTSPRGSHGRP 2333

Query: 937  SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                   +       T H      W+ + + ++  D   +  +G               G
Sbjct: 2334 PILPSSLRASGSGPSTGHPQPKVTWFKDGQPLASGDAHHVSPDG--ALLWVLHANLSSAG 2391

Query: 996  VIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVEINS-ETAD 1046
               C+  +   ++T    +    +P  +   +D   +E  V I     L  E  +  T  
Sbjct: 2392 HYACVAANAIGEKTKHFQLSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPT 2451

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103
            + W +DG   +   N    +       L I N    D G+Y+C++ +E   A       V
Sbjct: 2452 ITWMKDGVPFEALNN---IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEV 2508

Query: 1104 ELPPEII-------TRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS---EIQFSNHI 1152
             +PP I          ++  K    +  T E E        + W+KDG    E   + + 
Sbjct: 2509 LIPPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQ 2568

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAILTVEEPSINFTLR--LP 1203
            ++ I G+ + L+I    + D+G Y C   N            I   E P      R  + 
Sbjct: 2569 RVRILGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVT 2628

Query: 1204 EFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260
            E+  +  N  AYL   T  +P    ++TWY+    +   +  +++     R L I     
Sbjct: 2629 EYREIVENNPAYLYCDTNAVP--AAELTWYRGDRPLSIEDGVSVLQG--GRVLQIPLVRA 2684

Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFP 1315
            +D   Y+C   +      L  E++   P ++     +   E  +   S V+L       P
Sbjct: 2685 EDAGRYSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNP 2744

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P   W+ N   +      +  +      L +   E  DA  Y    EN  G  +    +
Sbjct: 2745 APTISWLQNG--LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAGSTEKLFTL 2802

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
             +  +P       I    +SS+++  D   +   S  + +  +   +   E I +   T 
Sbjct: 2803 RVQGEPG-LNPEQITATLNSSVSLPCDVRAHP--SPEVTWYKDGWTLSLGEEIFLLPGTH 2859

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
            T   +  ++   S  +   A+N             +K+++ + +      +P   +    
Sbjct: 2860 T-LQLTRVQLLDSGMYICEALNAAG--------RDHKLVQLSVLAPGAPSRPQDVVLVSA 2910

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAF 1553
             +   L+C     P+P V W +DG+ L   +                       Y C   
Sbjct: 2911 GDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQRLEIQDAQVSDKGLYSCRVS 2970

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612
            N  GE   +  + +Q  P  T  N + +   +V G   +++  + G+P P V W K+   
Sbjct: 2971 NAAGEAMRAFSLTVQVPP--TFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMP 3028

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +E+     + +  +   +++  L+   +  YT  A N    +  +  + V   P
Sbjct: 3029 VESSMARGVVS--RGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAP 3080



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 99/448 (22%), Positives = 171/448 (38%), Gaps = 36/448 (8%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C    +P P ++W   G  +    N      S        L+I        G YT 
Sbjct: 3736 VVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPS------GALEIGQALPIHTGRYTC 3789

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWC 769
             A N  G A   +VL ++        V++PL S++     E V+L  +  G PRP+I W 
Sbjct: 3790 AARNAAGMAHKHVVLTVQAS-----PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQ 3844

Query: 770  KNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            K    V A    +         L+   V  +D G Y   A+NS G A     + V+    
Sbjct: 3845 KEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQ---- 3900

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQNFDGE 886
                PP       ++++ E     L    T +P P +TW ++ + +S ++   T    G 
Sbjct: 3901 ---VPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSG- 3956

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
              EL++ N +S+ D+G Y C A N+ G++     +TI    V       +S    +   +
Sbjct: 3957 --ELLVKNSESQ-DAGTYTCTAENAVGRARRRVHLTILALPVFTTLPGDRSLRLGDKLWL 4013

Query: 947  ILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--- 1003
                + S T    W  N + ++  +   + ++              D G   C  ++   
Sbjct: 4014 HCAARGSPTPQIGWTVNNRLVTATE--GVSEQDGGSTLQRVAVTREDSGTYVCWAENRVG 4071

Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNK 1062
            +  +   V  + +P F  K QD  V+  D   L  + + E A  + W R G+ ++  +  
Sbjct: 4072 RVQAVSFVHVKGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRL 4131

Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
                       L++      D G Y C+
Sbjct: 4132 QTLPD----GSLWLERVEARDAGPYECV 4155



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 73/320 (22%), Positives = 130/320 (40%), Gaps = 19/320 (5%)

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            LI +A LSD GS   V            + +    PP+   + +   V     + LECR 
Sbjct: 1826 LIEQAQLSDAGSYRCVASNVVGSTELQYS-LRVNAPPSILGEEQNVSVVANESVALECRS 1884

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             A+P P ++W   G  + P   + ++ +       ++L++   +    G YT  A+N+ G
Sbjct: 1885 HAVPPPVLSWRKDGRPLEPRPGVYLSADK------ALLEVDRAEVGDTGRYTCEALNQVG 1938

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775
             +     L +      P +  EP +++ V +G    LS    G P P I+W K+ +P+  
Sbjct: 1939 RSEKHYNLNVWVPPVFPSR--EP-RTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPG 1995

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
            + +          +  L   +   EG YT +  N  G +     + V  P    A P   
Sbjct: 1996 EGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVP-PRIAGP--- 2051

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
            +  + +++V +     L    T  P P +TW R+   + P   +     G+++ +     
Sbjct: 2052 LEPYADVSVVQDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHV---ER 2108

Query: 896  DSEIDSGDYKCVASNSAGKS 915
                 +G Y CVA N AG++
Sbjct: 2109 AQPAHAGRYSCVAENEAGRA 2128



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 72/285 (25%), Positives = 116/285 (40%), Gaps = 21/285 (7%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP          + EG+  LL C     PEP + W   G+ +   +     I+      
Sbjct: 3901 VPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKG-KFTIQPS---- 3955

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L + N +    GTYT  A N  G A   + L I       P          +R G+ 
Sbjct: 3956 -GELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILA----LPVFTTLPGDRSLRLGDK 4010

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + L     G+P P I W  NN+ V A    S+ D  S         +D G Y   AEN  
Sbjct: 4011 LWLHCAARGSPTPQIGWTVNNRLVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRV 4070

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G  +  + + V+         P+F  + Q++TV+   ++ L  + +  P P++ W R  +
Sbjct: 4071 GRVQAVSFVHVKGV-------PVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQ 4123

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             +  S+ +    DG    L +  V++  D+G Y+CVA N  G ++
Sbjct: 4124 PVRASQRLQTLPDG---SLWLERVEAR-DAGPYECVAHNLLGSAT 4164



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 159/783 (20%), Positives = 280/783 (35%), Gaps = 69/783 (8%)

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            S +P+   +  G+ + L C     P P+I W   G  +   E+   A          VL+
Sbjct: 3360 SDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQGARR--------VLR 3411

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVI 753
            +  V+    G YT +A +  GE      ++++     PP VI    P   + +  G+ ++
Sbjct: 3412 VEGVQVSDAGLYTCLAHSPAGEVEKSFRIRVQA----PPNVIGSHGPRFVVGLAPGQ-LV 3466

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            L   V  +P P I W +    ++A       +      L+     D G Y+  A N+ G 
Sbjct: 3467 LECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQALSTADSGDYSCTAHNAAGS 3526

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
               +  + V  P   NA     +N+   +  +  G           P P ++W ++   +
Sbjct: 3527 TSLAFHVEVHRPPTVNAS----VNQTTLLPCQADGV----------PQPLVSWLKDGVPL 3572

Query: 874  SPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
             P  T      +G    L I  V +E D+G Y C+ASN AG    G  + +         
Sbjct: 3573 DPGSTRWVLAREGLREGLRIQPVLAE-DAGHYLCLASNPAGSDRQGRDLQVFEPPAIAPG 3631

Query: 933  HLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992
                +       ++  E   S      W+ + +++     +   +               
Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQ 3691

Query: 993  DVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVV- 1048
            D  + +C+V +   E   +  V   +P  I   Q DF        +L        A VV 
Sbjct: 3692 DSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVS 3751

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE 1104
            W + G  +  + N Y     G    L I        G Y+C  R+ +  A     +TV  
Sbjct: 3752 WSKAGTRLGVRGNGYRVSPSG---ALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQA 3808

Query: 1105 LP-----PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
             P     P ++  +  ++V    +A+    + +    + W K+G  +  +N    T    
Sbjct: 3809 SPVVKPLPSVVWAVAKEEVLLPCEAS---GIPRPS--IAWQKEGLSVPAANPGAGTQVLP 3863

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAY 1215
              +L+I     +DAG Y C   NS  +A+    L V+ P    T  LP+  +        
Sbjct: 3864 GGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKT-GLPDLSITEGAHALL 3922

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
                       VTW K    +   + KFT+        L+++     D   YTC   +A 
Sbjct: 3923 PCTATGSPEPKVTWEKDGQPVSGAKGKFTI---QPSGELLVKNSESQDAGTYTCTAENAV 3979

Query: 1275 STTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
               + +V +     P       +  ++ G  + L    +  P P   W VN++++   + 
Sbjct: 3980 GRARRRVHLTILALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATE- 4038

Query: 1334 TKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
                +  +    T+++V  T  D+G Y    EN  G       V +   P    KP  + 
Sbjct: 4039 ---GVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVHVKGVPVFQVKPQDVT 4095

Query: 1392 IDS 1394
            + S
Sbjct: 4096 VRS 4098



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 154/745 (20%), Positives = 276/745 (37%), Gaps = 72/745 (9%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++LEC + A P P+I W  +G  +  D +     E         L++  +     G Y+ 
Sbjct: 3465 LVLECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRF------LQLQALSTADSGDYSC 3518

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
             A N  G  SL   +++      PP V   +        ++ +L  Q  G P+P ++W K
Sbjct: 3519 TAHNAAGSTSLAFHVEVH----RPPTVNASVN-------QTTLLPCQADGVPQPLVSWLK 3567

Query: 771  NNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            +  P+    T+     +G    + I +P   +D G Y   A N  G       + V    
Sbjct: 3568 DGVPLDPGSTRWVLAREGLREGLRI-QPVLAEDAGHYLCLASNPAGSDRQGRDLQV---- 3622

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-FDG 885
                EPP        +T+       L    + +P P + W+++ + +     + Q  +  
Sbjct: 3623 ---FEPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLD--FRLQQGAYRL 3677

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
                 ++    S  DS  ++CV SN  G++     VT+ V     +   Q  +       
Sbjct: 3678 LPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA--IADDQTDFTATIMAP 3735

Query: 946  VILECQTSHT----VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            V+L C ++      VS      +  + G  +R +   G               G   C  
Sbjct: 3736 VVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYR-VSPSG---ALEIGQALPIHTGRYTCAA 3791

Query: 1002 KDQETSTMLVVKETIPE--FIRKLQDFE-VKEKDVAILEVEINS-ETADVVWERDGEIIK 1057
            ++        V  T+     ++ L        K+  +L  E +      + W+++G  + 
Sbjct: 3792 RNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSV- 3850

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEIITRLQ 1114
            P  N     +     +L I + S  D G Y C+ ++ + +A      VV++PP I T L 
Sbjct: 3851 PAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLP 3910

Query: 1115 NQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173
            +  + +G  A      T   +  V W KDG  +  +   + TI    + L + + +  DA
Sbjct: 3911 DLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKG-KFTIQPSGELL-VKNSESQDA 3968

Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-------PDETLD 1226
            G Y+C   N+   A   V        L LP F  +P +    L  ++          T  
Sbjct: 3969 GTYTCTAENAVGRARRRVHLT----ILALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQ 4024

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            + W     ++  TE    +S+    + + R   T +D   Y C   +     +    V V
Sbjct: 4025 IGWTVNNRLVTATEG---VSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVHV 4081

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            +  P      ++  ++ G  V L       P P  EW+   + ++  +  +   D    S
Sbjct: 4082 KGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRLQTLPDG---S 4138

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHA 1369
            L +++VE  DAG Y+    N  G A
Sbjct: 4139 LWLERVEARDAGPYECVAHNLLGSA 4163



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 126/618 (20%), Positives = 228/618 (36%), Gaps = 45/618 (7%)

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEI 1128
            R L I    + D G Y C+  +   + E+     V  PP I+   QN  V        E 
Sbjct: 1823 RVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVANESVALEC 1882

Query: 1129 EL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNS 1183
                    ++ W KDG  ++    + L+ D  K  L++   ++ D G Y+CE    VG S
Sbjct: 1883 RSHAVPPPVLSWRKDGRPLEPRPGVYLSAD--KALLEVDRAEVGDTGRYTCEALNQVGRS 1940

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
            +    L V  P + F  R P  + V     A L+ +          +KK       E  +
Sbjct: 1941 EKHYNLNVWVPPV-FPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGEGVS 1999

Query: 1244 LIS-DVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREY---R 1298
            L       R L + +     +  YTC   + A ++++ +  VV  PP+I      Y    
Sbjct: 2000 LAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPLEPYADVS 2059

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + +  + +L  +    P P   W  +   +     +   + +   SL +++ +   AG Y
Sbjct: 2060 VVQDEEASLECNATGKPAPRVTWERDGWPVG--PESGLRLQNHGQSLHVERAQPAHAGRY 2117

Query: 1359 KLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
                EN  G A+   ++++L + P P G     E     ++ C     + G+  ++    
Sbjct: 2118 SCVAENEAGRAERRFSLSVLGEDPQPSGGGQ--EAARQPLSPC-----SWGHLLVLPGAR 2170

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
                   +   S ++ ++ Q  +Q  L +  S    +Y + +    +  ET   Y V  E
Sbjct: 2171 PLANAALSG--SCEHCSQNQDRLQIALISLPSPHLNSYCIPQGGGEEWEETRREYLVPPE 2228

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY------E 1530
                      PL N+T   +  + L C   G+P P + W+R  + +   + TY       
Sbjct: 2229 LIGDL----GPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKI 2284

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKVGDE 1589
            +                Y C+A N+ GE      V +    P  +     I         
Sbjct: 2285 SGWMLKLTRAQEQDRGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPSSLRASG 2344

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
               +    G P P+V W+K+G  L +   ++++     +++ +     S +  Y   A+N
Sbjct: 2345 ---SGPSTGHPQPKVTWFKDGQPLASGDAHHVS--PDGALLWVLHANLSSAGHYACVAAN 2399

Query: 1650 TAGTSSVEVTLKVYDKPS 1667
              G  +    L V   P+
Sbjct: 2400 AIGEKTKHFQLSVLVVPT 2417



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 60/203 (29%), Positives = 92/203 (45%), Gaps = 20/203 (9%)

Query: 632  IPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            +PP F S++P+   V EG    L C    +P P I+W   G+ + P E +S+A  S +  
Sbjct: 1950 VPPVFPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPL-PGEGVSLAQVSAVGR 2008

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVR 747
               +L +   +  QEGTYT    N  G +S    L +      PP++   +EP   + V 
Sbjct: 2009 ---LLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYV----PPRIAGPLEPYADVSVV 2061

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
            Q E   L     G P P +TW ++  PV     L  ++ G +  +   +P      G Y+
Sbjct: 2062 QDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHA---GRYS 2118

Query: 805  LKAENSEGIAETSAVITV--EEP 825
              AEN  G AE    ++V  E+P
Sbjct: 2119 CVAENEAGRAERRFSLSVLGEDP 2141



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 68/338 (20%), Positives = 137/338 (40%), Gaps = 24/338 (7%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNI-LEIDSSS 1396
            +S ++S  I +    + G Y+    +  G    +  + +   P      PN+ +    ++
Sbjct: 446  ESGNSSWEIPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVPNVTVSPGETA 505

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            I  C    E   N T   +V +++ +  +    V  +      ++N   +   R++  A 
Sbjct: 506  ILSCLVLSEAPYNLT---WVRDWRVLSASTG-RVTQLADLSLEVRNTTPSDGGRYQCMAS 561

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N   ++ AS     + +++E    +P V    ++       ++ + C   G P P ++W 
Sbjct: 562  NSNGVTRAS----VWLLVRE----APQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWS 613

Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            R+G+ L+  ++   + +               Y C A N+ G  E +  +     P ++ 
Sbjct: 614  REGRALQEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSA 673

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
             N  +      G+E ++     G+PPP VIWY+       D E  +  ++  S ++RI  
Sbjct: 674  VNGVVLAAK--GEEAVLECEATGVPPPRVIWYR------GDLEMILAPEDSISGMLRIPV 725

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            ++   +  YT  A N  G +S E+ L+V   P   E P
Sbjct: 726  VRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELP 763



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 127/577 (22%), Positives = 212/577 (36%), Gaps = 65/577 (11%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE-- 1192
            + W KDG   +  N+IQL + G    L+I +   +DAG+Y+C V N    A+    VE  
Sbjct: 2452 ITWMKDGVPFEALNNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVL 2509

Query: 1193 -EPSINFTLRLPEFIL--VPANTDAYLTVE-----IPDETLDVTWYKK-----KSVIEDT 1239
              PSI+      E  +  V    ++ LT+E     +P  T  ++WYK      +  +   
Sbjct: 2510 IPPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPT--ISWYKDGQNLPEKPVTPN 2567

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYER-- 1295
            ++  ++ +   R L I+     D   Y CV  +   +      V + +F       E   
Sbjct: 2568 QRVRILGE--GRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARG 2625

Query: 1296 ---EYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
               EYR I   +   L  D  A P     W    + +        S+      L I  V 
Sbjct: 2626 GVTEYREIVENNPAYLYCDTNAVPAAELTWYRGDRPLSI--EDGVSVLQGGRVLQIPLVR 2683

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              DAG Y  +  N  G   +   + +L  P   G+   L ++  ++N          NST
Sbjct: 2684 AEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGETEEL-VEEVTVN---------ANST 2733

Query: 1412 I-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETT 1468
            + ++  V      T  W+           +Q L+     +     V +    +  A    
Sbjct: 2734 VSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPA 2793

Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
               + +   ++Q      P + IT   N  + L C     P P+VTWY+DG  L   +  
Sbjct: 2794 GSTEKLFTLRVQGEPGLNP-EQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEI 2852

Query: 1529 Y--ENRXXXXXXXXXXXXXXXYKCIAFN----DHGEVETSCVV-GIQQKPVITISNEDIK 1581
            +                    Y C A N    DH  V+ S +  G   +P      +D+ 
Sbjct: 2853 FLLPGTHTLQLTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRP------QDVV 2906

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
                 GD+ +++   +  P P V W K+G  L   +        +   + I++ + S   
Sbjct: 2907 LV-SAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQR--LEIQDAQVSDKG 2963

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPS--KPEGPVIMR 1676
             Y+   SN AG +    +L V   P+   PE  ++ R
Sbjct: 2964 LYSCRVSNAAGEAMRAFSLTVQVPPTFENPETEMVSR 3000



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 43/193 (22%), Positives = 72/193 (37%), Gaps = 9/193 (4%)

Query: 1479 IQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR----X 1533
            +Q+  V KPL ++      E++ L C   G+P+P + W ++G  +  A      +     
Sbjct: 3806 VQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGG 3865

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y C+A N  G       + +Q  P I     D+      G   L+ 
Sbjct: 3866 QLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLPDLSITE--GAHALLP 3923

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
                G P P+V W K+G  +   K     T + +  + +K  +   +  YT  A N  G 
Sbjct: 3924 CTATGSPEPKVTWEKDGQPVSGAK--GKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981

Query: 1654 SSVEVTLKVYDKP 1666
            +   V L +   P
Sbjct: 3982 ARRRVHLTILALP 3994



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
           R +    G  V+  C   GYP P I+W R+   ++     ++    D   TL+I+ V PE
Sbjct: 586 RSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRV----DAQGTLIIQGVAPE 641

Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           DAG+++C A N  G    T  L    P S
Sbjct: 642 DAGSYSCQAANEIGRDEETVTLYYTDPPS 670



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 11/181 (6%)

Query: 1507 GVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
            G PQPKVTW++DG+ L +  A +   +                Y C+A N  GE      
Sbjct: 2350 GHPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHFQ 2409

Query: 1565 VGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNI 1621
            + +   P ++ ++ + + ++  V     ++ + E    P P + W K+G   E     NI
Sbjct: 2410 LSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFE--ALNNI 2467

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE----GPVIMRE 1677
                 T  ++I   ++  + +YT   +N  G +     ++V   PS  +    G V M+E
Sbjct: 2468 QLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKE 2527

Query: 1678 I 1678
            +
Sbjct: 2528 V 2528



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 51/244 (20%), Positives = 89/244 (36%), Gaps = 12/244 (4%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            IQ +    +  +   A NE+   D    T YY          P+V      +     E+ 
Sbjct: 635  IQGVAPEDAGSYSCQAANEIG-RDEETVTLYYT-------DPPSVSAVNGVVLAAKGEEA 686

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             L C   GVP P+V WYR   ++  A     +                Y C A N+ G+ 
Sbjct: 687  VLECEATGVPPPRVIWYRGDLEMILAPEDSIS-GMLRIPVVRERDAGVYTCRAVNELGDA 745

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                 + +   P +    +D+  +  +G   L+     G P P + W++  ++    +  
Sbjct: 746  SAEIRLEVGHAPQLLELPQDVTVE--LGRSALLACRATGHPLPTITWHRGDDQPLGLRGS 803

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
              + +   S + + +     + +Y+   SNTAG+   +V L V  K      P     I+
Sbjct: 804  RHSIRADGS-LHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHIT 862

Query: 1680 RESV 1683
             E V
Sbjct: 863  NEGV 866



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F  K +      G +V   CQ  G P P + W R    ++ SQ  Q   D     +L 
Sbjct: 4085 PVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRLQTLPD----GSLW 4140

Query: 570  IREVFPEDAGTFTCVAKNAAGFAS 593
            +  V   DAG + CVA N  G A+
Sbjct: 4141 LERVEARDAGPYECVAHNLLGSAT 4164



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G+     C   G P P++TW +     +P    +  +       L+++    +DAGT+T
Sbjct: 3916 EGAHALLPCTATGSPEPKVTWEKDG---QPVSGAKGKFTIQPSGELLVKNSESQDAGTYT 3972

Query: 583  CVAKNAAGFASSTTELIVEA 602
            C A+NA G A     L + A
Sbjct: 3973 CTAENAVGRARRRVHLTILA 3992



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 530  ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
            EC   G P P++TW R    + P    ++    ++  +L +    P  AG ++CVA+N A
Sbjct: 2069 ECNATGKPAPRVTWERDGWPVGPESGLRL---QNHGQSLHVERAQPAHAGRYSCVAENEA 2125

Query: 590  GFASSTTELIV 600
            G A     L V
Sbjct: 2126 GRAERRFSLSV 2136



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 2/115 (1%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
            E ++++   EK  +    + P+F  +  R     +G   +  C   G P P+I+W +   
Sbjct: 1932 EALNQVGRSEKHYNLNVWVPPVFPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQ 1991

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             + P +   +         L +    P   GT+TC   N AG +S   +L+V  P
Sbjct: 1992 PL-PGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVP 2045



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 5/100 (5%)

Query: 503  SEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            S E  +AP  +  E L    T  G ++   C   G P P I W +      P+++    +
Sbjct: 1506 SVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNG---HPAEELPGVH 1562

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                  TL I  V    AG F C A N AG A++  EL V
Sbjct: 1563 VTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSV 1602



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTC 583
            S +   C+  G P P I WFR    + P ++ + +     +   L +     +D G ++C
Sbjct: 2245 SPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKISGWMLKLTRAQEQDRGLYSC 2304

Query: 584  VAKNAAGFA--SSTTELIVEAPLSDHG 608
            +A N AG A    + E++  +P   HG
Sbjct: 2305 LASNEAGEARRDFSVEVLGTSPRGSHG 2331



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
            EK  +L V+  PT E     P  V+ +       G  +  EC   GYP P ++W+ +   
Sbjct: 1408 EKTTRLEVYVPPTIEGTGEGPRVVKAVA------GRPLTLECVARGYPPPTVSWYHEGL- 1460

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
              P  D    +       L +  +     G ++CVA + AG A
Sbjct: 1461 --PVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 1501



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F      +    G  +   C   G P PQI W     ++  ++      + D  +TL 
Sbjct: 3994 PVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATEGVS---EQDGGSTLQ 4050

Query: 570  IREVFPEDAGTFTCVAKNAAG 590
               V  ED+GT+ C A+N  G
Sbjct: 4051 RVAVTREDSGTYVCWAENRVG 4071



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-DDDNVATLV-IREVFPEDAGTF 581
           G     EC+  G P P++ W+R         D +M    +D+++ ++ I  V   DAG +
Sbjct: 683 GEEAVLECEATGVPPPRVIWYR--------GDLEMILAPEDSISGMLRIPVVRERDAGVY 734

Query: 582 TCVAKNAAGFASSTTELIV 600
           TC A N  G AS+   L V
Sbjct: 735 TCRAVNELGDASAEIRLEV 753



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 541  ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            I+WF+    I  + D  M   D  V  L+I +    DAG++ CVA N  G       L V
Sbjct: 1801 ISWFKGRQPIS-AWDRAMVSTDGRV--LLIEQAQLSDAGSYRCVASNVVGSTELQYSLRV 1857

Query: 601  EAPLSDHGSEMTV 613
             AP S  G E  V
Sbjct: 1858 NAPPSILGEEQNV 1870


>UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 551

 Score =  148 bits (359), Expect = 1e-33
 Identities = 157/613 (25%), Positives = 263/613 (42%), Gaps = 94/613 (15%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F++ ++P    +G T  FEC V+GYPRP I WF+    +K ++     Y +  +++L 
Sbjct: 1    PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTY-EGALSSLT 59

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            I +   +D G + CVA+N+ G AS  TEL+       +G+                    
Sbjct: 60   INQCTIDDEGNYKCVARNSFGKASCATELLTNL----NGTHTHPPHF------------- 102

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
              I   F   P A+  +EG D+ LE R+   P+P + WL   E I+   +  V+  +D+H
Sbjct: 103  --IDKHFETAP-AEVTEEG-DVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVH 158

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 L I +  +   G Y V+A N  G AS    + +   E +P   +E LK       
Sbjct: 159  ----TLVINSPNQDDIGQYKVIASNHRGMASRTFDVNV---EGKPKPSVEWLK------- 204

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
                       + RP +    ++  +K   T+ D D +S+TI +P K  DEG+YT+K  N
Sbjct: 205  -----------DDRPVL----SDSHIKM--TEED-DIYSLTIREPTK-SDEGMYTVKITN 245

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G    +  + VE+ T  ++  P       E T  E+G ++L  ++T  PVP ++W ++
Sbjct: 246  DVGSGTRTFDVKVEDTTTNDSFVPF------EST--EEGNVRLSVKITGKPVPEVSWTKD 297

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KV 928
             + +   + I  +   +   L I       DSG YKC  +N AGKS+    V I+ E K 
Sbjct: 298  EKPVHKIQNIRLDHQDDIYTLTIREATPN-DSGSYKCTLTNDAGKSTRTFSVEIEGETKP 356

Query: 929  TFVKHLQKSYE--TEEGKTVILECQTSHTV--------STKWYHNKKEISGMDHREIIQE 978
               K  ++  +   EE   V  E +   T         S +W+ +   +S  +H  I +E
Sbjct: 357  EKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEE 416

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQ------------ETSTMLVVKETI-PEFIR--KL 1023
                          D G     V ++            + +   + K+ + P+FI     
Sbjct: 417  DGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSF 476

Query: 1024 QDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSV 1081
              F+  ++    L V++  +   +V W +DG+ +    N + D ++  +I  L IR  S 
Sbjct: 477  VPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYI--LTIREASP 534

Query: 1082 HDEGEYSCILRDE 1094
             D G Y C L  +
Sbjct: 535  DDSGSYRCTLTSD 547



 Score =  119 bits (287), Expect = 8e-25
 Identities = 147/577 (25%), Positives = 236/577 (40%), Gaps = 74/577 (12%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITI 791
            PQ I+ ++ + V +G++      V G PRP+I W KN  P+K    + +  +G   S+TI
Sbjct: 1    PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 60

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT---VKEKG 848
                 + DEG Y   A NS G A + A   +      +  PP FI++  E     V E+G
Sbjct: 61   -NQCTIDDEGNYKCVARNSFGKA-SCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEG 118

Query: 849  TIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
             ++L  RV  +P PS+ W +++E+I  SP   ++ + D   +  ++ N  ++ D G YK 
Sbjct: 119  DVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHAD---VHTLVINSPNQDDIGQYKV 175

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKE 966
            +ASN  G +S     T DV                EGK            S +W  + + 
Sbjct: 176  IASNHRGMASR----TFDV--------------NVEGKP---------KPSVEWLKDDRP 208

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTMLV-VKETIPEFIRKLQ 1024
            +    H ++ +E              D G+    I  D  + T    VK           
Sbjct: 209  VLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFV 268

Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
             FE  E+    L V+I  +   +V W +D + +   +N    + +  I  L IR  + +D
Sbjct: 269  PFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQN-IRLDHQDDIYTLTIREATPND 327

Query: 1084 EGEYSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGN---------KATFEIELT-- 1131
             G Y C L +++  +  T  VE+  E           +G           A  E+E+T  
Sbjct: 328  SGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQ 387

Query: 1132 ---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SK 1184
               K    V WFKD   +    HI +T +     L I +    D G Y+ EV N     +
Sbjct: 388  VTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGR 447

Query: 1185 CTAILTVEE--PSINFTLRLPEFI----LVPANT----DAYLTVEIPDE-TLDVTWYKKK 1233
             T  ++V++   +I      P+FI     VP  +    D  LTV++  +   +VTW K  
Sbjct: 448  RTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDG 507

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
              ++      L     +  L IR+ + DD   Y C L
Sbjct: 508  KPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTL 544



 Score =  101 bits (242), Expect = 2e-19
 Identities = 74/286 (25%), Positives = 137/286 (47%), Gaps = 25/286 (8%)

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           E  ++ L  ++   P P+++W    + +   +NI +  + D++     L I        G
Sbjct: 274 EEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIY----TLTIREATPNDSG 329

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEP----PQVIE--PLKS--MIVRQGESVILSAQV 758
           +Y     N  G+++    ++I+ GE +P    P   E  PL+   + V     V ++AQV
Sbjct: 330 SYKCTLTNDAGKSTRTFSVEIE-GETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQV 388

Query: 759 VGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
            G P+P++ W K++ PV        T+ DG T+S+ I +P K KDEG YT++  N  G+ 
Sbjct: 389 TGKPQPSVEWFKDDVPVSPDEHITITEEDG-TYSLVIKEPTK-KDEGTYTVEVSNEAGLG 446

Query: 815 ETSAVITVEEPTE---ENAEPPLFIN--RFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
             +  ++V++  +   ++A  P FI    F      ++G ++L  +VT  P P +TW ++
Sbjct: 447 RRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKD 506

Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            + +     +  +   +   L I     + DSG Y+C  ++  GKS
Sbjct: 507 GKPVDKLPNVELDHQEDRYILTIREASPD-DSGSYRCTLTSDVGKS 551



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 104/512 (20%), Positives = 195/512 (38%), Gaps = 61/512 (11%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE- 1285
            + W+K    +++ E+     +    +L I +CT DD+  Y CV  ++        E++  
Sbjct: 32   IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLTN 91

Query: 1286 ------FPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
                   PP  +D   E     +    DV L V     P+P+ +W+ + ++I    H   
Sbjct: 92   LNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMV 151

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
            S  +   +L I      D G YK+   N+ G A    +V +  KP    KP++  +    
Sbjct: 152  SSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGKP----KPSVEWLKD-- 205

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
                 D P  + +       ++  E D    ++++  TK+   +  +K  +         
Sbjct: 206  -----DRPVLSDSH------IKMTEEDDIYSLTIREPTKSDEGMYTVKITN--------- 245

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
               D+   + T +        K++  T         +    ++ L+    G P P+V+W 
Sbjct: 246  ---DVGSGTRTFD-------VKVEDTTTNDSFVPFESTEEGNVRLSVKITGKPVPEVSWT 295

Query: 1517 RDGK---KLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
            +D K   K++  +  +++                 YKC   ND G+   +  V I+ +  
Sbjct: 296  KDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETK 355

Query: 1573 ITISNEDIKQKHKVGDEWL---------VTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
                    ++   + +E L         +TA + G P P V W+K+   +  D+   IT 
Sbjct: 356  PEKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITE 415

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
            ++ T  + IKE  +     YT+E SN AG       + V D         +  +   +  
Sbjct: 416  EDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGS 475

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
             + ++   D+G + LT     K EP+   W K
Sbjct: 476  FVPFQ-STDEGDVRLTVKVTGKPEPEVT-WTK 505



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 75/314 (23%), Positives = 127/314 (40%), Gaps = 44/314 (14%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           DE  YT  +   +        V  + T+   S  P        + T +G+ V+   ++ G
Sbjct: 235 DEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFVPF-------ESTEEGN-VRLSVKITG 286

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
            P P+++W +    +   Q+ ++ + DD + TL IRE  P D+G++ C   N AG ++ T
Sbjct: 287 KPVPEVSWTKDEKPVHKIQNIRLDHQDD-IYTLTIREATPNDSGSYKCTLTNDAGKSTRT 345

Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
             + +E        + T                 EG P    + P    V   +++ +  
Sbjct: 346 FSVEIEGETKPEKGKPTER---------------EGKPLEEEELP----VSAETEVEMTA 386

Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
           ++   P+P + W      + PDE+I++  E   +     L I    K  EGTYTV   N 
Sbjct: 387 QVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYS----LVIKEPTKKDEGTYTVEVSNE 442

Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----------SVILSAQVVGNPRPT 765
            G       + +    K  P+  + +K   +  G            V L+ +V G P P 
Sbjct: 443 AGLGRRTFDVSVDDTRKTIPK--DAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPE 500

Query: 766 ITWCKNNKPVKALP 779
           +TW K+ KPV  LP
Sbjct: 501 VTWTKDGKPVDKLP 514



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 110/493 (22%), Positives = 179/493 (36%), Gaps = 61/493 (12%)

Query: 934  LQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            L +  E  EG+T   EC        S +W+ N   +   +      EG            
Sbjct: 6    LMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTI 65

Query: 992  XDVGVIKCIVKDQ--------ETSTMLVVKETIP-EFIRK---LQDFEVKEKDVAILEVE 1039
             D G  KC+ ++         E  T L    T P  FI K       EV E+    LEV 
Sbjct: 66   DDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVR 125

Query: 1040 INSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098
            +       V W +D E+I    + +       +  L I + +  D G+Y  I  +    A
Sbjct: 126  VGGHPKPSVQWLKDDEVIISSPH-FMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMA 184

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157
                                      TF++ +  K    V W KD   +   +HI++T +
Sbjct: 185  S------------------------RTFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEE 220

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY-- 1215
                 L I +    D G Y+ ++ N   +   T +   +  T     F+   +  +    
Sbjct: 221  DDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDV-KVEDTTTNDSFVPFESTEEGNVR 279

Query: 1216 LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
            L+V+I  + + +V+W K +  +   +   L       TL IR+ T +D   Y C L +  
Sbjct: 280  LSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDA 339

Query: 1273 AKSTTKLKVEVV--EFPPKIVDYEREYR--------IKRGSDVTLLVDYQAFPQPNDEWI 1322
             KST    VE+     P K    ERE +        +   ++V +       PQP+ EW 
Sbjct: 340  GKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWF 399

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA----DVEMNVTIL 1378
             +   +   +H   + +  + SL IK+    D G Y + + N  G      DV ++ T  
Sbjct: 400  KDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRK 459

Query: 1379 DKPSPPGKPNILE 1391
              P    KP  +E
Sbjct: 460  TIPKDAVKPKFIE 472



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 132/583 (22%), Positives = 217/583 (37%), Gaps = 67/583 (11%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            P+ I  +Q  +V +G  ATFE  + KG     + WFK+G  ++ +  I  T +G    L 
Sbjct: 1    PQFIDLMQPVEVTEGQTATFECTV-KGYPRPSIEWFKNGLPLKENERIASTYEGALSSLT 59

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFT-LRLPEFI-----LVPANT----D 1213
            I  C +DD G Y C   NS   A    E   ++N T    P FI       PA      D
Sbjct: 60   INQCTIDDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGD 119

Query: 1214 AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              L V +       V W K   VI  +  F + S     TL+I    +DD  +Y  +  +
Sbjct: 120  VRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASN 179

Query: 1273 AKSTTKLKVEV-VEFPPK-IVDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
             +       +V VE  PK  V++ ++ R +   S + +  +   +     E   + + + 
Sbjct: 180  HRGMASRTFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMY 239

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
              K T   + S + +  + KVE+T      +  E+     +V ++V I  KP P      
Sbjct: 240  TVKITN-DVGSGTRTFDV-KVEDTTTNDSFVPFEST-EEGNVRLSVKITGKPVP------ 290

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
                     + W + E          V + Q I       +  +T     I+    N S 
Sbjct: 291  --------EVSWTKDEKP--------VHKIQNIRLDHQDDIYTLT-----IREATPNDSG 329

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPL--KNITTEPNEDIELTCIFG 1506
             ++    N+   S  + + E     K  K +    E KPL  + +      ++E+T    
Sbjct: 330  SYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQVT 389

Query: 1507 GVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGEVETS 1562
            G PQP V W++D   +   +    T E+                 Y     N+ G    +
Sbjct: 390  GKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRT 449

Query: 1563 CVVGIQQKPVITISNEDIKQK---------HKVGDEWLV--TAVIEGIPPPEVIWYKNGN 1611
              V +      TI  + +K K          +  DE  V  T  + G P PEV W K+G 
Sbjct: 450  FDVSVDDTRK-TIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGK 508

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             ++      +  +E   ++ I+E     S  Y    ++  G S
Sbjct: 509  PVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 551



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 41/178 (23%), Positives = 68/178 (38%), Gaps = 12/178 (6%)

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGE 1558
            C   G P+P + W+++G  LK  +   +TYE                  YKC+A N  G+
Sbjct: 22   CTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 81

Query: 1559 VETSCVV-----GIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611
               +  +     G    P   I         +V +E  V   +   G P P V W K+  
Sbjct: 82   ASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDE 141

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
             + +   + +++      + I    +    +Y + ASN  G +S    + V  KP KP
Sbjct: 142  VIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGKP-KP 198



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 6/120 (5%)

Query: 476 DENNYTQYLQKK--LNEKIDKLPVFE-KPTSEEQSMAPIFVE--KLRPKHTPDGSTVQFE 530
           DE  YT  +  +  L  +   + V + + T  + ++ P F+E     P  + D   V+  
Sbjct: 431 DEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLT 490

Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            +V G P P++TW +    +    + ++ + +D    L IRE  P+D+G++ C   +  G
Sbjct: 491 VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRY-ILTIREASPDDSGSYRCTLTSDVG 549


>UniRef50_UPI00005A1317 Cluster: PREDICTED: similar to eEF1A2 binding
            protein; n=3; Canis lupus familiaris|Rep: PREDICTED:
            similar to eEF1A2 binding protein - Canis familiaris
          Length = 1264

 Score =  147 bits (355), Expect = 4e-33
 Identities = 90/379 (23%), Positives = 165/379 (43%), Gaps = 9/379 (2%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K G    V    +   P +  W K+G ++   + +   +   +  + + +    R    +
Sbjct: 562  KAGKPVTVKIPFQSHLPVQAAWKKDGVEVAGGSGRGPQVALGDGFTRLCLPSAGRKDGGQ 621

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y++  S+  G++  EVTL+V DKP  P+GP+ +++     V + W+PP DDGG  L +Y 
Sbjct: 622  YSVTLSSEGGSARAEVTLQVIDKPQPPQGPLEVQDRHGAGVCLHWRPPRDDGGQALERYV 681

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761
            +E+ +   + W+KV +   D  T+    + +  +Y FRV A    G  EALES E +V  
Sbjct: 682  VERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAEVLVAP 741

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXX 1820
             AL  P             ++ + +TW      G + I+ Y +E +++G   W       
Sbjct: 742  EALPRPPSAPAIQAA---SSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWTAVNAQP 798

Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                R  +  +     Y+FR+ A +  G   P    D +     +  P   R   V++++
Sbjct: 799  VPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVRELQVTDTS 858

Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
              S+TL W  P++  G     Y++E +   G  W+             ++ ++ ++    
Sbjct: 859  HTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLRPQEGYFV 918

Query: 1939 RISAENTVGVSLPTESQSV 1957
            R++A N  G   PT   +V
Sbjct: 919  RVTAVNDGGRGQPTALDTV 937



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 90/430 (20%), Positives = 164/430 (38%), Gaps = 21/430 (4%)

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            S EV +     P  P  P I +  S + +T+ W  P   G   +  Y IEK +  +N W 
Sbjct: 734  SAEVLVAPEALPRPPSAPAI-QAASSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWT 792

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXX 1773
             V         + +  + + C+Y FRV A +P G  E    S+ +  +  + VP      
Sbjct: 793  AVNAQPVPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVREL 852

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXXXARIQKLS 1830
                   + S+ ++W P +   G     Y VE++  +G +W              ++ L 
Sbjct: 853  QVTDT-SHTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLR 911

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-- 1888
                Y  R+ A N+ G   P   D   T+ + +    +P+ F++   T  S  ++  +  
Sbjct: 912  PQEGYFVRVTAVNDGGRGQPTALD---TVVQAMPVTVRPK-FLMDSGTKDSRMVRAGDTV 967

Query: 1889 --PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946
              P S   +PI   +   K         + +    + +  I      D  ++ +   +  
Sbjct: 968  RVPISFEAAPIPE-VTWLKDGLPLPKRNVTSTKEGLTQLLIPAASLSDSGLYTVVLRSLQ 1026

Query: 1947 GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
            G    T   S+R+   A  P  P  P+ ++      V   W     + G   L Y + +R
Sbjct: 1027 GEEA-TYRFSLRV---AACPRAP-GPIRLQENVPGTVTAEWEASPDEAGEDPLYYEVLMR 1081

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
               +  W +     V+T  +    +   H Y  R+ A+NE+G S P ++ EP+++     
Sbjct: 1082 SSARGRWQQAAD-RVHTNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEPWRIPRHRD 1140

Query: 2067 SHADEEPGEQ 2076
                + PG +
Sbjct: 1141 KFTVKAPGHR 1150



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 65/285 (22%), Positives = 109/285 (38%), Gaps = 9/285 (3%)

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT--TYQFRIY 1840
            V + W P   +GG  +  Y VE +Q G+  W                 +     Y FR+ 
Sbjct: 662  VCLHWRPPRDDGGQALERYVVERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVR 721

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
            A    G      S + +   + L  PPS P    +  ++S+ +TL WT P   G + I  
Sbjct: 722  AVTSEGAGEALESAEVLVAPEALPRPPSAP---AIQAASSQGITLTWTAPRGPGSAHILG 778

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TESQSVR 1958
            Y+IE +     +WT +           + ++++  +  FR++A +  G   P   S +V 
Sbjct: 779  YLIEKRKKGSNTWTAVNAQPVPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVF 838

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
                  VP P    L++       +  SW  P+   G    GY + +R      W     
Sbjct: 839  ARDPMRVPGP-VRELQVTDTSHTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHP 897

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
              V    F ++ L     Y +R+ A N+ G  +P   D   + +P
Sbjct: 898  GTVPATTFTVKGLRPQEGYFVRVTAVNDGGRGQPTALDTVVQAMP 942



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 92/396 (23%), Positives = 155/396 (39%), Gaps = 27/396 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438
            P PP  P I    S  I + W  P   G++ I+ Y++E ++  +  W +V  + + + + 
Sbjct: 745  PRPPSAPAIQAASSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWTAVNAQPVPERRW 804

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            ++ +++    Y FR  AV+     +    ++        ++  P  E     +T   +  
Sbjct: 805  TVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVREL---QVTDTSHTS 861

Query: 1499 IELTCI-----FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCI 1551
            I L+        G   Q  V   R    L+ +                      Y  +  
Sbjct: 862  ITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLRPQEGYFVRVT 921

Query: 1552 AFNDHGEVETSCVVGIQQKPVITI-------SNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
            A ND G  + + +  + Q   +T+       S     +  + GD   V    E  P PEV
Sbjct: 922  AVNDGGRGQPTALDTVVQAMPVTVRPKFLMDSGTKDSRMVRAGDTVRVPISFEAAPIPEV 981

Query: 1605 IWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKV 1662
             W K+G  L    + N+T TKE  + + I     S S  YT+   +  G  +    +L+V
Sbjct: 982  TWLKDGLPLP---KRNVTSTKEGLTQLLIPAASLSDSGLYTVVLRSLQGEEATYRFSLRV 1038

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
               P  P GP+ ++E    +VT EW+   D+ G +   Y +        RW + AD    
Sbjct: 1039 AACPRAP-GPIRLQENVPGTVTAEWEASPDEAGEDPLYYEVLMRSSARGRWQQAAD-RVH 1096

Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEP 1757
               Y    +    EY FRV+A+N +G S   + SEP
Sbjct: 1097 TNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEP 1132



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 9/178 (5%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAG 1356
            +K G  VT+ + +Q+       W  +   +       P +        L +      D G
Sbjct: 561  VKAGKPVTVKIPFQSHLPVQAAWKKDGVEVAGGSGRGPQVALGDGFTRLCLPSAGRKDGG 620

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINIC--WDEPENTGNSTII 1413
             Y + L +  G A  E+ + ++DKP PP  P  LE+ D     +C  W  P + G   + 
Sbjct: 621  QYSVTLSSEGGSARAEVTLQVIDKPQPPQGP--LEVQDRHGAGVCLHWRPPRDDGGQALE 678

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             YVVE ++   + W+ V       T+    +++    Y FR  AV      +A E+ E
Sbjct: 679  RYVVERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAE 736



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            S  P F+  LR    P G      C V+G+PRP +TWF+    +          D   V 
Sbjct: 1155 SQKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSL-AGHPTAYSTDVLGVC 1213

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +LVI  V   D G +  VA+NA G A ST  LIV
Sbjct: 1214 SLVIPSVSLRDGGQYKAVAENALGQAVSTATLIV 1247



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 3/113 (2%)

Query: 1948 VSLPTESQSVRLEKHATV---PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
            V+L +E  S R E    V   P PP  PLE++      V   W  P  DGG  L  Y + 
Sbjct: 624  VTLSSEGGSARAEVTLQVIDKPQPPQGPLEVQDRHGAGVCLHWRPPRDDGGQALERYVVE 683

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             R   ++ W++VG+   ++  F    + +   Y  R+ A    G  E LES E
Sbjct: 684  RRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAE 736



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 52/247 (21%), Positives = 97/247 (39%), Gaps = 18/247 (7%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++ G  V + + ++A P P   W+ +   + K   T  S       L I     +D+G+Y
Sbjct: 961  VRAGDTVRVPISFEAAPIPEVTWLKDGLPLPKRNVT--STKEGLTQLLIPAASLSDSGLY 1018

Query: 1359 KLRLENNCGH-ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
             + L +  G  A    ++ +   P  PG   + E    ++   W+   +      +YY V
Sbjct: 1019 TVVLRSLQGEEATYRFSLRVAACPRAPGPIRLQENVPGTVTAEWEASPDEAGEDPLYYEV 1078

Query: 1418 EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV--- 1473
              +      W    +   T   +   +     Y FR  A NE+  S  S+T+E +++   
Sbjct: 1079 LMRSSARGRWQQAADRVHTNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEPWRIPRH 1138

Query: 1474 -----IKETKIQSPTV-EKP-----LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
                 +K    + P + +KP     L+        +  ++C   G P+P VTW++D + L
Sbjct: 1139 RDKFTVKAPGHREPDLSQKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSL 1198

Query: 1523 KTAKATY 1529
                  Y
Sbjct: 1199 AGHPTAY 1205



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 2/101 (1%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--T 790
            + P+ +  L++ ++ QG    +S  V G PRP +TW K+++ +   PT    D   +   
Sbjct: 1156 QKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSLAGHPTAYSTDVLGVCSL 1215

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            ++    ++D G Y   AEN+ G A ++A + V    EE  E
Sbjct: 1216 VIPSVSLRDGGQYKAVAENALGQAVSTATLIVVGREEEEEE 1256


>UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopalladin
            - Homo sapiens (Human)
          Length = 1320

 Score =  147 bits (355), Expect = 4e-33
 Identities = 98/375 (26%), Positives = 179/375 (47%), Gaps = 17/375 (4%)

Query: 472  QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
            Q LM+E  + +  +  ++E  D++   E PT +   +APIF ++L+     +GS V F C
Sbjct: 910  QRLMNEIEF-RLERTPVDESDDEIQHDEIPTGK--CIAPIFDKRLKHFRVTEGSPVTFTC 966

Query: 532  QVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            ++ G P P++ WF+    I K ++  +M  + D   +L I     +D G +T +A N  G
Sbjct: 967  KIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQG 1026

Query: 591  FASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPKAQYVDE 647
              S +  L+V++ P+    +                 + L+     P F + P      E
Sbjct: 1027 RISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHE 1086

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEG 706
            G    L+C++  +P P++ WL  G+ ++PD +  + + E+ +H     L I  + +   G
Sbjct: 1087 GRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHS----LLIDPLTQRDAG 1142

Query: 707  TYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            TY  +A N+ G+ S  + L +   E K+ P ++E L++  V +G  V L  +V+G P P 
Sbjct: 1143 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPV 1202

Query: 766  ITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
              W K+N+ +    + +    D   ++  +++P K  D G YTL A+N  GI   +A + 
Sbjct: 1203 FYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLD 1262

Query: 822  VEEPTEENAEPPLFI 836
            +         PP+ +
Sbjct: 1263 IYAQWHHQIPPPMSV 1277



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 91/329 (27%), Positives = 141/329 (42%), Gaps = 45/329 (13%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHM 690
            I P F K+ K   V EGS +   C++V IP P + W   G++I   +E+  +  E D   
Sbjct: 943  IAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT- 1001

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEAS---------LPIVLKIKTG----------- 730
             CS L I +     +G YT++A N +G  S         LPI  ++ +            
Sbjct: 1002 -CS-LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059

Query: 731  --EKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
              +KEP       P  ++    M+  +G    L  +V G P P +TW  N +PV  LP  
Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPV--LPDA 1117

Query: 782  S------DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
            S      +   HS+ ++ P   +D G Y   A N  G  + S  + +    +E  + P+ 
Sbjct: 1118 SHKMLVRETGVHSL-LIDPLTQRDAGTYKCIATNKTG--QNSFSLELSVVAKEVKKAPVI 1174

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITN 894
            + + Q   V E   ++L  RV   P P   W ++NE I    E I+ + D      ++  
Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1234

Query: 895  VDSEIDSGDYKCVASNSAGKSSHGARVTI 923
               + D+G Y   A N AG  S  AR+ I
Sbjct: 1235 PAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 47/142 (33%), Positives = 71/142 (50%), Gaps = 9/142 (6%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------D 561
           AP+F + L+     +G  V FEC+V+G P P++ W+R+  +I+ S DF++         +
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXX 619
            + + TLVI EVF ED+G FTC A N  G  SS  +L V     LS++GS  +       
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNL 553

Query: 620 XXXXXXADILEGIPPTFSKKPK 641
                        PP+  + PK
Sbjct: 554 AAIEPQPSPPHSEPPSVEQPPK 575



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 37/107 (34%), Positives = 57/107 (53%), Gaps = 2/107 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           E     P F +KLR +  P+G+ VQ +C V G P PQ+ W+ +   ++ S D  +     
Sbjct: 263 EPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI-VQAG 321

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
           N+ +L I E F ED G ++C A N  G  S++ E+ +E  +S   SE
Sbjct: 322 NLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-VSSSDSE 367



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 58/259 (22%), Positives = 108/259 (41%), Gaps = 33/259 (12%)

Query: 726  KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTK 781
            +I TG+   P   + LK   V +G  V  + ++VG P P + W K+ K +         +
Sbjct: 936  EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMR 995

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE------------------ 823
             +GD      ++     D+G YT+ A N +G    S  + V+                  
Sbjct: 996  REGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGR 1055

Query: 824  --------EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
                    EP +E    P F+    ++   E    +L  +V+  P P +TW  N + + P
Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLP 1115

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTFVK 932
              +         +  ++ +  ++ D+G YKC+A+N  G++S    +++   +V+K   + 
Sbjct: 1116 DASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1175

Query: 933  HLQKSYETEEGKTVILECQ 951
               ++    EG  V LEC+
Sbjct: 1176 EKLQNCGVPEGHPVRLECR 1194



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 49/177 (27%), Positives = 75/177 (42%), Gaps = 18/177 (10%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXX----XXXXXXXYKCIAFND 1555
            L C   G+P P++TW  +G+  L  A      R                   YKCIA N 
Sbjct: 1092 LDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNK 1151

Query: 1556 HGE----VETSCVVG-IQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
             G+    +E S V   +++ PVI   + N  + + H V  E  V     G+PPP   W K
Sbjct: 1152 TGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVI----GMPPPVFYWKK 1207

Query: 1609 NGNKLENDKEYNITTKEKT--SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            +   +   +E     ++ T  + + I+  K+S +  YT+ A N AG  S    L +Y
Sbjct: 1208 DNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 4/90 (4%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           G PP F++K +++ V EG+ + L+C +V IP P + W  +G+E+    +I +    ++H 
Sbjct: 266 GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS 325

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
               L I    +   G Y+  A N  G  S
Sbjct: 326 ----LTIAEAFEEDTGRYSCFASNIYGTDS 351



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            ++ GIPPP+V WY  G +LEN  + +I        + I E     + +Y+  ASN  GT 
Sbjct: 291  IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTD 350

Query: 1655 SVEVTLKVYD-KPSKPEGPVIMREISR 1680
            S    + +     S  EG     E++R
Sbjct: 351  STSAEIYIEGVSSSDSEGDPNKEEMNR 377



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 4/102 (3%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSI 789
           +PP+  + L+S  V +G  V L   VVG P P + W    K ++  P       G+ HS+
Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 326

Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           TI +  + +D G Y+  A N  G   TSA I +E  +  ++E
Sbjct: 327 TIAEAFE-EDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE 367



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 5/151 (3%)

Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
           P+ A  T+ +   H++   + K+ + E   +  A        + + +  EEP     +PP
Sbjct: 214 PIPA-DTRDNEVNHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPL---GQPP 269

Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893
            F  + +   V E   ++L   V   P P + WY   + +  S  I     G    L I 
Sbjct: 270 RFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIA 329

Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
               E D+G Y C ASN  G  S  A + I+
Sbjct: 330 EAFEE-DTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G+PPPE+ W  NG  +  D  + +  +E     + I  L +  +  Y   A+N  G +
Sbjct: 1096 VSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN 1155

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678
            S  + L V  K  K + PVI+ ++
Sbjct: 1156 SFSLELSVVAKEVK-KAPVILEKL 1178



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%)

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            +S ++ YY+   E   Q P   + L++        ++L CI  G+P P+V WY +GK+L+
Sbjct: 254  SSPSSLYYE---EPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELE 310

Query: 1524 TAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             +   +     N                Y C A N +G   TS  + I+
Sbjct: 311  NSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQN-----FDG 885
           P+F    Q ++  E   +    RV   P P + WYR   +I  SP   I Q       + 
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494

Query: 886 ENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           E I  LVI  V +E DSG + C ASN  G  S  A++ +
Sbjct: 495 EEICTLVIAEVFAE-DSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 19/60 (31%), Positives = 30/60 (50%)

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
            D S+    +  I   K  +P  +K LK+        +  TC   G+P PKV W++DGK++
Sbjct: 926  DESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQI 985



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 1106 PPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP    +L++++V +G +   + I +      VRW+ +G E++ S  I +   G    L 
Sbjct: 268  PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            I +   +D G YSC   N
Sbjct: 328  IAEAFEEDTGRYSCFASN 345



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 2/76 (2%)

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNT 1650
            T  I GIP P+V W+K+G ++    E+    +E   T  + I+         YTI A+N 
Sbjct: 965  TCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANP 1024

Query: 1651 AGTSSVEVTLKVYDKP 1666
             G  S    L V   P
Sbjct: 1025 QGRISCSGHLMVQSLP 1040



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 15/41 (36%), Positives = 22/41 (53%)

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            I +P   K L+N++    + +   C   G P PKV WYR+G
Sbjct: 432  IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 472



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 11/113 (9%)

Query: 1561 TSCVVGIQQKPVITISN-EDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDK 1617
            T+ + G+  KP+I       + Q     +  LV     ++G P P+V WY+ G  +E+  
Sbjct: 420  TNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSP 479

Query: 1618 EYNITTK--------EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            ++ I  K        E+   + I E+    S  +T  ASN  GT S    L V
Sbjct: 480  DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 45/191 (23%), Positives = 77/191 (40%), Gaps = 16/191 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D    E  +  L+ +++     ++ W  +G+ + P  +     +   +  L 
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y CI  ++    S + E++V    V+  P I+ +LQN  V +G+    E
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192

Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQK-LKIYDCDLDDAGEYSC----EV 1180
               +     +  W KD   I  +   I +  D      L I      DAG Y+     E 
Sbjct: 1193 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252

Query: 1181 GNSKCTAILTV 1191
            G   CTA L +
Sbjct: 1253 GIVSCTARLDI 1263


>UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep:
            CG17800-PAN - Drosophila melanogaster (Fruit fly)
          Length = 2037

 Score =  145 bits (351), Expect = 1e-32
 Identities = 282/1393 (20%), Positives = 516/1393 (37%), Gaps = 155/1393 (11%)

Query: 746  VRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDG--DTHSITILKPKKVKDEG 801
            +RQ  ++ +       P P   W K       K     +D         I+K   V+D G
Sbjct: 260  IRQDRTIAIFCPAQAYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSG 319

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
             Y     NS G      V+TV  P     +PP     F    V          + T NP+
Sbjct: 320  KYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAV-------FTCQYTGNPI 372

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
             +++W ++ + I  SE +          L I +V  E D G Y+C   N    +   A +
Sbjct: 373  KTVSWMKDGKAIGHSEPV----------LRIESVKKE-DKGMYQCFVRNDQESAEASAEL 421

Query: 922  TIDVE-KVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREI--- 975
             +        ++   +    E G +V L+C    + T    W  + K+I+  D  ++   
Sbjct: 422  KLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQY 481

Query: 976  --IQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVK 1029
              +                D G+ KCI K +    E S  L V   +P +IR+++   + 
Sbjct: 482  VTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV-YGLP-YIRQMEKKAIV 539

Query: 1030 EKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
              +  I+   +     D +VWERD   +   + +  F     I +   RN+   D+  Y+
Sbjct: 540  AGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNS---DQATYT 596

Query: 1089 CILRDE---SCTAEVTV-VELPPEIIT-RLQNQKVNKGNKATFEIELTKGDALVRWF--- 1140
            C+ +++   S    + V V +PP+++      + +N  +  +    + KGD  +  +   
Sbjct: 597  CVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTT 656

Query: 1141 -----KDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
                      +  ++ I +T   ++   L I          Y+C V  +    I    E 
Sbjct: 657  APDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTC-VARNAAGVIYHTAEL 715

Query: 1195 SINFTLRLPEFILVPAN------TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISD 1247
             +N     P +IL P +      +DA +  +        VTW K         K    SD
Sbjct: 716  RVNVP---PRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSD 772

Query: 1248 ---VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302
               V++ TL +    + ++  Y C  ++      + + +  V+ PP+  +  R    +RG
Sbjct: 773  NIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRG 832

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK------SASLTIKKVENTDAG 1356
                L  + +        W +N+  +      + +I  +       +SL+IK+ E +D+ 
Sbjct: 833  EPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSA 892

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            ++     N  G  D  +N+ + + P  P    +L+    S+ + W +P + GNS +  Y+
Sbjct: 893  LFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYD-GNSPLDRYI 951

Query: 1417 VEYQEIDTTEWISVKNIT----KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
            +E++      W  +  +      T+  +Q L   ++Y  R  A N +  S +SE      
Sbjct: 952  IEFKR-SRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEA----- 1005

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW------YRDGKKLKTAK 1526
            V   T  ++P+  KP +NI  EP     +   +   P P+  W      Y  G KL    
Sbjct: 1006 VTIITAEEAPS-GKP-QNIKVEPVNQTTMRVTW--KPPPRTEWNGEILGYYVGYKLSNTN 1061

Query: 1527 ATY---------ENRXXXXXXXXXXXXXXXYKCI--AFNDHG-------EVETSCVVGIQ 1568
            ++Y         E                 Y  +  AFN  G       E + +      
Sbjct: 1062 SSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPS 1121

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEG----IPPPEVIWYKNGNKLENDKEYNITTK 1624
            Q P  T       Q  +VG  W V+  +E     I   +V++  +    +  K +   T 
Sbjct: 1122 QPPSDTACTTLTSQTIRVG--W-VSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTA 1178

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--SRES 1682
               +V+    LK+  +    + A+   G     V +    +P  PE P  ++ +     +
Sbjct: 1179 SSDTVLH--GLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAA 1236

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            + + W+PP    G+ +T+Y +           K   V     ++   +L +N  Y F V 
Sbjct: 1237 ILVSWRPPAQPNGI-ITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVT 1295

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            A   +G  E  +S+ IV   +  VP+             +  +   F  +++   P +  
Sbjct: 1296 ASTTIG--EGQQSKSIVAMPSDQVPAKIASF--------DDTFTATF--KEDAKMPCL-- 1341

Query: 1803 KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD----DKIT 1858
             V   Q    WK          R++ L  + +   +   R + G    +  +    D IT
Sbjct: 1342 AVGAPQPEITWKIKGVEFSANDRMRVLP-DGSLLIKSVNRQDAGDYSCHAENSIAKDSIT 1400

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
                +  P Q  +  +S +T+ ++T+K  +P     +P+  Y + +K   G+  T  V+V
Sbjct: 1401 HKLIVLAPPQSPHVTLSATTTDALTVK-LKPHEGDTAPLHGYTLHYKPEFGEWETSEVSV 1459

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
                 +H IE +          +  N +G    ++  + R +     P  P  P  I  V
Sbjct: 1460 DS--QKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTK--GQKPKLPEKPRFIE-V 1514

Query: 1979 GSNIVMTSWGTPEW-DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
             SN V  S     W DGG P+  + +  +   +  W ++         + + DL     Y
Sbjct: 1515 SSNSV--SLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWY 1572

Query: 2038 MIRIYARNEIGLS 2050
             +RI A N  G +
Sbjct: 1573 NLRITAHNSAGFT 1585



 Score =  128 bits (308), Expect = 2e-27
 Identities = 226/1035 (21%), Positives = 400/1035 (38%), Gaps = 87/1035 (8%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEV-TVVELPPEIITRLQ--NQKVNKGNKATFEIEL 1130
            L I++  V D G+Y C++ +      V TV+ +   +  ++    Q V+ G  A F  + 
Sbjct: 308  LIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQY 367

Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189
            T      V W KDG  I  S  +      KK+   +Y C + +  E +      K     
Sbjct: 368  TGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGG-- 425

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF------T 1243
              + P I    +  E  + P  +     V   + T +++W      I + +++      T
Sbjct: 426  RFDPPVIRQAFQ--EETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVT 483

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY--RIKR 1301
            +  DV    L I     +D   Y C+   AKS    KV V E   K+  Y   Y  ++++
Sbjct: 484  VNGDVVSY-LNITSVHANDGGLYKCI---AKS----KVGVAEHSAKLNVYGLPYIRQMEK 535

Query: 1302 GSDV---TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE-NTDAGI 1357
             + V   TL+V       P D  IV  +  +     +      + +L I+ VE N+D   
Sbjct: 536  KAIVAGETLIVTCPVAGYPIDS-IVWERDNRALPINRKQKVFPNGTLIIENVERNSDQAT 594

Query: 1358 YKLRLENNCGHA---DVEMNVTILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412
            Y    +N  G++    +E+ V +  +  P   G+  I   D  S   C     N G++ +
Sbjct: 595  YTCVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSAT-C---TVNKGDTPL 650

Query: 1413 IYYVVEYQEIDTTEWISVKN----ITKTQTSIQNLKTNSSY-RFRAYAVNEVDISDASET 1467
              Y     +  T     + N    ITKT   I  L   S + R RA   N   ++  +  
Sbjct: 651  ELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRA---NYTCVARNAAG 707

Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGK 1520
              Y+       +    + +P      +   D ++ C   G P+P+VTW +       + K
Sbjct: 708  VIYHTAELRVNVPPRWILEPTDKAFAQ-GSDAKVECKADGFPKPQVTWKKAVGDTPGEYK 766

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNED 1579
             LK +                      Y C A N  G  +    ++ +Q  P  T    +
Sbjct: 767  DLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRN 826

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKT----SVIRIK 1633
              Q  + G+  ++    +G  P  ++W  N  +L+  ND  Y I  +  +    S + IK
Sbjct: 827  --QTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIK 884

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
              +RS S+ +T  A+N  G+    + + V + P  P    ++ +  R SV + W  P  D
Sbjct: 885  RTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGR-SVQLSWAQPY-D 942

Query: 1694 GGLELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            G   L +Y IE  +     W ++    V        +QKL+    Y  R++A+N +G S+
Sbjct: 943  GNSPLDRYIIE-FKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQ 1001

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGG--SPIIDYKVEI 1806
            +  SE + I TA + PS          ++  ++ +TW P   +E NG      + YK+  
Sbjct: 1002 S--SEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSN 1059

Query: 1807 KQEGKKWKX----XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
                  ++               +Q L + T Y   I A N+IG   P + ++K    + 
Sbjct: 1060 TNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAG-PLSEEEKQFTAEG 1118

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
             TP   P +   +  TS+++ + W  P  ES  G   T  ++   + +    TK      
Sbjct: 1119 -TPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKT 1177

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
            +  +  +  +K+      ++ A    G  +   S  +  +    VP  PT  ++  ++G+
Sbjct: 1178 ASSDTVLHGLKKYTNYTMQVLATTAGGDGV--RSVPIHCQTEPDVPEAPT-DVKALVMGN 1234

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
              ++ SW  P    G  +  Y +  +        +  KV    + F   +L +N  Y   
Sbjct: 1235 AAILVSWRPPAQPNGI-ITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFW 1293

Query: 2041 IYARNEIGLSEPLES 2055
            + A   IG  +  +S
Sbjct: 1294 VTASTTIGEGQQSKS 1308



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 86/334 (25%), Positives = 133/334 (39%), Gaps = 36/334 (10%)

Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDIL 652
           S T +I +A + D G  + V              +L    P  +K  P  Q VD G   +
Sbjct: 305 SGTLIIKDAVVEDSGKYLCVVNNSVGGESVET--VLTVTAPLSAKIDPPTQTVDFGRPAV 362

Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
             C+    P   ++W+  G+ I   E               VL+I +VKK  +G Y    
Sbjct: 363 FTCQYTGNPIKTVSWMKDGKAIGHSE--------------PVLRIESVKKEDKGMYQCFV 408

Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW---- 768
            N +  A     LK+  G  +PP + +  +   +  G SV L     GNP P I+W    
Sbjct: 409 RNDQESAEASAELKLG-GRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDG 467

Query: 769 ---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
                N++         +GD  S   +      D G+Y   A++  G+AE SA + V   
Sbjct: 468 KKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV--- 524

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
                 P  +I + ++  +    T+ +   V   P+ SI W R+N  + P     + F  
Sbjct: 525 ---YGLP--YIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRAL-PINRKQKVF-- 576

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            N  L+I NV+   D   Y CVA N  G S+ G+
Sbjct: 577 PNGTLIIENVERNSDQATYTCVAKNQEGYSARGS 610



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 274/1332 (20%), Positives = 477/1332 (35%), Gaps = 164/1332 (12%)

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            ++ T   + + EP    A      + F   ++++  TI +       PVP   WY+  E 
Sbjct: 229  LSATKGRLVITEPVGSVAPRVNKKDGFSHDSIRQDRTIAIFCPAQAYPVPFYRWYKFIEG 288

Query: 873  ISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +  + +  N   + +   +   D+ + DSG Y CV +NS G  S      + V      
Sbjct: 289  TTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGES--VETVLTVTAPLSA 346

Query: 932  KHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            K    +   + G+  +  CQ T + + T  W  + K I    H E +             
Sbjct: 347  KIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIG---HSEPV-------LRIESV 396

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETI-----PEFIRKLQDFEVKE--KDVAILEVEINS 1042
               D G+ +C V++ + S     +  +     P  IR+    E  E    V +  V   +
Sbjct: 397  KKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGN 456

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIR---KLYIRNTSVH--DEGEYSCILRDESCT 1097
             T ++ WE DG+ I    ++Y   +   +      Y+  TSVH  D G Y CI + +   
Sbjct: 457  PTPEISWELDGKKI-ANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGV 515

Query: 1098 AE----VTVVELPPEIITRLQNQKVNKGNK--ATFEIELTKGDALVRWFKDGSEIQFSNH 1151
            AE    + V  LP   I +++ + +  G     T  +     D++V W +D   +  +  
Sbjct: 516  AEHSAKLNVYGLP--YIRQMEKKAIVAGETLIVTCPVAGYPIDSIV-WERDNRALPINRK 572

Query: 1152 IQLTIDG--------KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203
             ++  +G        +      Y C   +   YS   G+ +   ++  +    +F     
Sbjct: 573  QKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSAR-GSLEVQVMVPPQVVPFDFG---E 628

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF-----TLISDVKKR--TLIIR 1256
            E I +     A  TV   D  L++ W           +       LI+   +R   L I 
Sbjct: 629  ETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIE 688

Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
                  +  YTCV  +A        E+ V  PP+ +    +    +GSD  +      FP
Sbjct: 689  SVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKADGFP 748

Query: 1316 QPNDEW---IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG----- 1367
            +P   W   + ++    K      +I  +  +L +  ++ T+ G Y     N  G     
Sbjct: 749  KPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSA 808

Query: 1368 ------HADVEMNVTILDKPSPPGKPNILEIDSSS---INICWD------EPENTGNSTI 1412
                   A  E    + ++ +  G+P +L+ ++     I I W+      +P+N    TI
Sbjct: 809  VIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTI 868

Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
                   +EI +T  +S  +I +T+ S        S  F   A N     DAS       
Sbjct: 869  ------REEILSTGVMSSLSIKRTERS-------DSALFTCVATNAFGSDDAS----INM 911

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
            +++E     P +   LK +  +    ++L+          +  Y    K   A  +  +R
Sbjct: 912  IVQEV----PEMPYALK-VLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDR 966

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI----KQKHKVGD 1588
                                +N     E +       + V  I+ E+      Q  KV  
Sbjct: 967  VIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEP 1026

Query: 1589 EWLVTAVIEGIPPP------EVIWYKNGNKLEN-DKEY-----NITTKE-KTSVIRIKEL 1635
                T  +   PPP      E++ Y  G KL N +  Y     N  T+E K   + ++ L
Sbjct: 1027 VNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNL 1086

Query: 1636 KRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW-KPPL 1691
            +        I+A N  G    S  E        PS+P        ++ +++ + W  PPL
Sbjct: 1087 RVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPL 1146

Query: 1692 DDGGLELTKYAI------EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
            +     +  Y +      E ++     + K A  D       +  L +   Y  +V+A  
Sbjct: 1147 ESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDT-----VLHGLKKYTNYTMQVLATT 1201

Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
              G  + + S PI  +T  DVP           + N ++ ++W P  +  G  I  Y V 
Sbjct: 1202 AGG--DGVRSVPIHCQTEPDVPE-APTDVKALVMGNAAILVSWRPPAQPNGI-ITQYTVY 1257

Query: 1806 IKQEGKKWKXXXX---XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
             K EG + +                +L  N  Y+F + A   IG         K  +   
Sbjct: 1258 SKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEG----QQSKSIVA-- 1311

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTE--PESNGGSPITNYIIEFKTVKGKSWTKI-VTVG 1919
              P  Q    + S   + + T K     P    G+P      + K V+  +  ++ V   
Sbjct: 1312 -MPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPD 1370

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
            GS+    I+++  +D   +   AEN    S+  +S + +L     V +PP +P       
Sbjct: 1371 GSL---LIKSVNRQDAGDYSCHAEN----SIAKDSITHKL----IVLAPPQSPHVTLSAT 1419

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039
            +   +T    P     APL GY +  +      W E  +V V++ K NI  L     Y +
Sbjct: 1420 TTDALTVKLKPHEGDTAPLHGYTLHYKPEFGE-W-ETSEVSVDSQKHNIEGLLCGSRYQV 1477

Query: 2040 RIYARNEIGLSE 2051
                 N IG  E
Sbjct: 1478 YATGFNNIGAGE 1489



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 103/483 (21%), Positives = 197/483 (40%), Gaps = 39/483 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH-MY 691
            PP   +  + + ++ G  + L+C     P P+I+W   G++I  ++   V     ++   
Sbjct: 429  PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDV 488

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             S L IT+V     G Y  +A ++ G A     L +       P + +  K  IV  GE+
Sbjct: 489  VSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV----YGLPYIRQMEKKAIV-AGET 543

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            +I++  V G P  +I W ++N+ +     +      ++ I   ++  D+  YT  A+N E
Sbjct: 544  LIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQE 603

Query: 812  GI-AETSAVITVEEPTE----ENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPS-- 863
            G  A  S  + V  P +    +  E  + +N     T    KG   L    T  P P+  
Sbjct: 604  GYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTG 663

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +    +N+ I  ++T TQ     +IE V           +Y CVA N+AG   H A + +
Sbjct: 664  VGRLMSNDGILITKT-TQRISMLSIESVHAR-----HRANYTCVARNAAGVIYHTAELRV 717

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG-- 979
            +V     ++   K++   +G    +EC+          W     +  G +++++ +    
Sbjct: 718  NVPPRWILEPTDKAF--AQGSDAKVECKADGFPKPQVTWKKAVGDTPG-EYKDLKKSDNI 774

Query: 980  --RXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033
                           + G   C     +    ++ +++  +  PEF  KL++   +  + 
Sbjct: 775  RVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEP 834

Query: 1034 AILEVEINSE-TADVVWERDGEIIKPKK-NKYDFEKR----GHIRKLYIRNTSVHDEGEY 1087
            A+L+ E   E    ++W  +   + PK  N+Y   +     G +  L I+ T   D   +
Sbjct: 835  AVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALF 894

Query: 1088 SCI 1090
            +C+
Sbjct: 895  TCV 897



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 57/239 (23%), Positives = 101/239 (42%), Gaps = 14/239 (5%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
           L +E+  + H +  T             A++   +PP +  +P  +   +GSD  +EC+ 
Sbjct: 685 LSIESVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKA 744

Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
              P+P + W  K     P E   +    ++ +    L + N++K  EG Y   A+N  G
Sbjct: 745 DGFPKPQVTWK-KAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIG 803

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
            + L  V+ I    + PP+  E L++   R+GE  +L  +  G     I W  NN  +  
Sbjct: 804 -SGLSAVIMISV--QAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDP 860

Query: 778 LPTK---------SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
                        S G   S++I + ++  D  ++T  A N+ G  + S  + V+E  E
Sbjct: 861 KNDNRYTIREEILSTGVMSSLSIKRTER-SDSALFTCVATNAFGSDDASINMIVQEVPE 918



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 7/84 (8%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV----ATLVIREVFPEDAGTF 581
           T+   C  + YP P   W++    I+ +   Q    +D V     TL+I++   ED+G +
Sbjct: 265 TIAIFCPAQAYPVPFYRWYK---FIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKY 321

Query: 582 TCVAKNAAGFASSTTELIVEAPLS 605
            CV  N+ G  S  T L V APLS
Sbjct: 322 LCVVNNSVGGESVETVLTVTAPLS 345



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           ++ ++  K    G T+   C V GYP   I W R    +  ++  +++ +     TL+I 
Sbjct: 529 YIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPN----GTLIIE 584

Query: 572 EV-FPEDAGTFTCVAKNAAGF-ASSTTELIVEAP 603
            V    D  T+TCVAKN  G+ A  + E+ V  P
Sbjct: 585 NVERNSDQATYTCVAKNQEGYSARGSLEVQVMVP 618



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 7/102 (6%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV- 565
           ++ P ++ +   K    GS  + EC+ +G+P+PQ+TW  + A+     +++     DN+ 
Sbjct: 718 NVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTW--KKAVGDTPGEYKDLKKSDNIR 775

Query: 566 ---ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI-VEAP 603
               TL +  +   + G + C A N  G   S   +I V+AP
Sbjct: 776 VEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAP 817



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 64/282 (22%), Positives = 113/282 (40%), Gaps = 17/282 (6%)

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            +KK+   T  V+A    G+    + +  +T E + P+    +K++++    ++++S +  
Sbjct: 1187 LKKYTNYTMQVLATTAGGDGVRSVPIHCQT-EPDVPEAPTDVKALVMGNA-AILVSWRPP 1244

Query: 760  GNPRPTIT-WCKNNKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE-T 816
              P   IT +   +K   A   TK+    H     +  +++    Y      S  I E  
Sbjct: 1245 AQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQ 1304

Query: 817  SAVITVEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
             +   V  P+++    P  I  F +  T   K   K+       P P ITW       S 
Sbjct: 1305 QSKSIVAMPSDQ---VPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSA 1361

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
            ++ +    DG    L+I +V+ + D+GDY C A NS  K S   ++ +     +   H+ 
Sbjct: 1362 NDRMRVLPDGS---LLIKSVNRQ-DAGDYSCHAENSIAKDSITHKLIVLAPPQS--PHVT 1415

Query: 936  KSYETEEGKTVILECQTSHTVSTKWY--HNKKEISGMDHREI 975
             S  T +  TV L+     T     Y  H K E    +  E+
Sbjct: 1416 LSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEV 1457



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-- 567
           P F EKLR +    G     +C+ +G     I W      + P  D +    ++ ++T  
Sbjct: 818 PEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGV 877

Query: 568 ---LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
              L I+     D+  FTCVA NA G   ++  +IV+
Sbjct: 878 MSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQ 914



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM----YYDDDNV 565
           P+  +  + +    G +V  +C   G P P+I+W      I  +  +Q+      + D V
Sbjct: 430 PVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVV 489

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           + L I  V   D G + C+AK+  G A  + +L V
Sbjct: 490 SYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV 524



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C   G P+P+ITW  +      +   ++  D     +L+I+ V  +DAG ++C A+N+  
Sbjct: 1340 CLAVGAPQPEITWKIKGVEFSANDRMRVLPD----GSLLIKSVNRQDAGDYSCHAENSIA 1395

Query: 591  FASSTTELIVEAP 603
              S T +LIV AP
Sbjct: 1396 KDSITHKLIVLAP 1408



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 3/87 (3%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
            KP  P KP  +E+ S+S+++ + +    G   + ++VVE ++ D  EW  + N  K   +
Sbjct: 1502 KPKLPEKPRFIEVSSNSVSLHF-KAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNN 1560

Query: 1440 --IQNLKTNSSYRFRAYAVNEVDISDA 1464
              + +L+  + Y  R  A N    + A
Sbjct: 1561 YVVLDLEPATWYNLRITAHNSAGFTVA 1587


>UniRef50_P54296 Cluster: Myomesin-2; n=33; Euteleostomi|Rep:
            Myomesin-2 - Homo sapiens (Human)
          Length = 1465

 Score =  144 bits (348), Expect = 3e-32
 Identities = 111/403 (27%), Positives = 171/403 (42%), Gaps = 13/403 (3%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE 1724
            P  P G V   EISR  V + W+PP   G   L  Y IEK    +  W +V A       
Sbjct: 511  PGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGTWQRVNAQTAVRSP 568

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
             Y +  L E   Y+FRV++ N  G SE  E + PI  +    VPS              S
Sbjct: 569  RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKT-S 627

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
            V + W          ++ Y V+    G   W+          R  +  L+    Y FR+ 
Sbjct: 628  VVVQW--DRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N +G S      D I +   LT PS P    +      S+TL W  P+ +GGSPI  Y
Sbjct: 686  AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959
             ++ + V  K+W ++ +         ++ + E     F+I+A N  G+  P++ S+  + 
Sbjct: 746  YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805

Query: 1960 EKHATVPSP-PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
            E   T+P P P   L    V    ++  W  P + G +P+ GY +  R+     W+ V +
Sbjct: 806  EAW-TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVDQ 864

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
                +    + DL +  TY+ R+ A N  G+ +P ++ EP  V
Sbjct: 865  TTTASRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 9/163 (5%)

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
            QP  EW  +  ++K+ K TK       ASL+   +   D G+Y LR+ +  G  D    +
Sbjct: 311  QPRAEWYRDDLLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFL 370

Query: 1376 TILDK----PSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
             + D        PG P  L+   ++   + + W  P  T  S ++ Y V+  E+ T  W+
Sbjct: 371  FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430

Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
               +  +   +  +  L    SY FR  AVN   IS  S  ++
Sbjct: 431  QCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSD 473



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 31/224 (13%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P +    ++    V + W  P +   SP+  Y ++   V   +W +       + ++
Sbjct: 383  PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPT---------------ESQSVRLEKH-------- 1962
             +  + E    IFR+ A N+ G+S P+                 Q+V LE          
Sbjct: 443  PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502

Query: 1963 -----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV- 2016
                 A VP PPT  +    +  N V+ SW  P   G  PL+ Y I    V    W  V 
Sbjct: 503  DLEGDAQVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGTWQRVN 560

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             +  V + ++ + DL E  +Y+ R+ + N  GLSEP E   P +
Sbjct: 561  AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ 604



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 66/316 (20%), Positives = 116/316 (36%), Gaps = 46/316 (14%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
            ++P +   L++ T      ++L     G P P V WY+DG  +  A    + R       
Sbjct: 152  RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGV 211

Query: 1540 XXXXX-------XXXYKCIAFNDHGEVETSCV-------------------VGIQQKPVI 1573
                           Y  +A N HG+V T+                     +G+    +I
Sbjct: 212  HTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMI 271

Query: 1574 TISNEDIKQKHKVGDEW-------------LVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
              ++ D++   K G  +             LVT  ++ + P    WY++   L+  K   
Sbjct: 272  PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQP-RAEWYRDDLLLKESKWTK 330

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP----SKPEGPVIMR 1676
            +   E  + +    L +     YT+   +  G +     L V D        P  P+ ++
Sbjct: 331  MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFLFVRDADPLVTGAPGAPMDLQ 390

Query: 1677 --EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
              + +R+ V + WKPP       +  Y +++ E   N W++  D    +  Y +  L E 
Sbjct: 391  CHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEG 450

Query: 1735 CEYMFRVIAQNPVGFS 1750
              Y+FRV A N  G S
Sbjct: 451  RSYIFRVRAVNSAGIS 466



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 7/177 (3%)

Query: 1881 SVTLKWT---EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
            +VTLK T    P+     P   +  +   +K   WTK+    G        ++ + DE +
Sbjct: 294  TVTLKCTMLVTPDLKRVQPRAEWYRDDLLLKESKWTKMFFGEGQA-SLSFSHLHKDDEGL 352

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGG 1995
            + +   +  GV+  +    VR +    V   P AP++++   +N   V+ +W  P     
Sbjct: 353  YTLRIVSRGGVTDHSAFLFVR-DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            +P++GY +   +V    W++     V   K+ +  L E  +Y+ R+ A N  G+S P
Sbjct: 412  SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 57/239 (23%), Positives = 103/239 (43%), Gaps = 27/239 (11%)

Query: 493 DKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551
           DKL  +E+ T EE+ S AP  + +LR     +  +V+    V+G+P P + W++  ++I 
Sbjct: 137 DKL-AWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLIC 195

Query: 552 PSQDFQMYYDDDN--VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV------EAP 603
            + +   Y  + N  V TL I     +D  T++ VA NA G  S+   ++V      E P
Sbjct: 196 QAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEP 255

Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-- 661
               G  + +               LE    TF +        EG  + L+C ++  P  
Sbjct: 256 FRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR--------EGETVTLKCTMLVTPDL 307

Query: 662 ---EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
              +P   W ++ + ++ +   +     +     + L  +++ K  EG YT+  V+R G
Sbjct: 308 KRVQPRAEW-YRDDLLLKESKWTKMFFGEGQ---ASLSFSHLHKDDEGLYTLRIVSRGG 362



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 62/306 (20%), Positives = 121/306 (39%), Gaps = 17/306 (5%)

Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
            +  N   +DV      L  PS P    +L  D  S+ + W  P+ +G S I+ Y ++ +E
Sbjct: 692  MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751

Query: 1422 IDTTEWISVKNITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            +    W  V +     T  ++  L   S Y F+  AVN   I + S+ +E++K    T  
Sbjct: 752  VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811

Query: 1480 Q-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD------GKKLKTAKATYENR 1532
            +  P  +     +       +    ++ G   P   ++ D      G+ +   + T  +R
Sbjct: 812  EPGPAYDLTFCEVRDTSLVMLWKAPVYSG-SSPVSGYFVDFREEDAGEWITVDQTTTASR 870

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589
                           ++  A N +G     +TS  V ++ +P     +  + ++   G+ 
Sbjct: 871  -YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQ---GNI 926

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
            +L     E     +  W K+  ++ +D+ + I T    S + +K   +     Y++  S+
Sbjct: 927  YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSD 986

Query: 1650 TAGTSS 1655
            T G SS
Sbjct: 987  TDGVSS 992



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 1/78 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNT 1650
            +T  + G P PEVIW+KN   ++  + +++  ++   V + IK +    S KY+I   N 
Sbjct: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNK 1423

Query: 1651 AGTSSVEVTLKVYDKPSK 1668
             G   ++VT+ VY    K
Sbjct: 1424 YGGEKIDVTVSVYKHGEK 1441



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 37/193 (19%), Positives = 78/193 (40%), Gaps = 5/193 (2%)

Query: 403  KRLNPFEIFYTP--VEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQK 460
            K  +P ++  TP  + ++C    F     V    +   +   E + I  +    W  + +
Sbjct: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292

Query: 461  HLTEEKGWVPAQYLMDENNYTQYLQ---KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR 517
               ++KG    +    ++N+ + L    +  +E   +   F+     E++   +      
Sbjct: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352

Query: 518  PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
                 +G T+   C V G P P++ WF+    I+ S+ F +  +     ++ I+ V  ED
Sbjct: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412

Query: 578  AGTFTCVAKNAAG 590
            +G ++   KN  G
Sbjct: 1413 SGKYSINIKNKYG 1425



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 8/155 (5%)

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSK 1668
            +N  E N ++  K +++ +  L      ++ I A N AG       S     + +  P  
Sbjct: 755  KNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEP 813

Query: 1669 -PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
             P   +   E+   S+ + WK P+  G   ++ Y ++  E D   WI V           
Sbjct: 814  GPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVDQTTTASRYLK 873

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761
            +  L +   Y+FRV A N  G  +  + SEP++++
Sbjct: 874  VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE 908



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 8/106 (7%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P    + EG  + L C +   P+P++ W    ++I   E+ SV +E   ++  ++  +T+
Sbjct: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEK----EPPQVIEP 740
                  G Y++   N+ G   + + + + K GEK     PPQ  +P
Sbjct: 1411 E---DSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKP 1453



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GENIELVITNVDSEID 900
            +T+ E  T+ L   V  NP P + W++N++ I  SE  +   +  + + + I  V SE D
Sbjct: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-D 1412

Query: 901  SGDYKCVASNSAGKSSHGARVTI 923
            SG Y     N  G       V++
Sbjct: 1413 SGKYSINIKNKYGGEKIDVTVSV 1435



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 6/102 (5%)

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVK 1431
            +VT++  PS PG+        +S+ + WD P++     ++ Y V+     T  W   + K
Sbjct: 607  DVTVV--PSAPGRVLASRNTKTSVVVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHK 662

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             I   +  +  L T   Y FR  AVN V +S+ S+ ++  KV
Sbjct: 663  PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKV 704



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI 1357
            I  G  + L       P P   W  N + I+  +H    ++ +K  S+TIK V + D+G 
Sbjct: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415

Query: 1358 YKLRLENNCGHADVEMNVTI 1377
            Y + ++N  G   +++ V++
Sbjct: 1416 YSINIKNKYGGEKIDVTVSV 1435



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 8/102 (7%)

Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII----SPSE-TITQ 881
           E  +  P  + R +  TV E+ ++KL   V   P P + WY++  +I     P +  I  
Sbjct: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207

Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           N+    +E+   + D   D+  Y  VA+N+ G+ S  A V +
Sbjct: 208 NYGVHTLEINRADFD---DTATYSAVATNAHGQVSTNAAVVV 246



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-- 1438
            P PP   +  EI  + + + W+ P   G   ++Y+ +E   + +  W  V   T  ++  
Sbjct: 511  PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF-IEKSVVGSGTWQRVNAQTAVRSPR 569

Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             ++ +L    SY FR  + N   +S+ SE T
Sbjct: 570  YAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 4/102 (3%)

Query: 731  EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDT 786
            EK   ++I  L  ++ + +G+++ L+  V GNP P + W KN++ ++       K +   
Sbjct: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            +    +K    +D G Y++  +N  G  +    ++V +  E+
Sbjct: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEK 1441


>UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15;
            Endopterygota|Rep: CG32387-PA, isoform A - Drosophila
            melanogaster (Fruit fly)
          Length = 1770

 Score =  142 bits (344), Expect = 9e-32
 Identities = 302/1398 (21%), Positives = 513/1398 (36%), Gaps = 133/1398 (9%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITIL 792
            P V+E    + V Q E  +L     G P P  +W  +N   P+  L          I  +
Sbjct: 204  PSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWFTHNGAGPLPVLSGPRVRLLGPILAI 263

Query: 793  KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            +    +D GVY   A N  G A     +TV  P +    P +       ++V   GT + 
Sbjct: 264  EAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNV-------LSVHMGGTAEF 316

Query: 853  VARVTRNPVP----SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
               VT N  P    +I WY++   +  S  +          LV+  V  E + G Y+CV 
Sbjct: 317  RCLVTSNGSPVGMQNILWYKDGRQLPSSGRVEDT-------LVVPRVSRE-NRGMYQCVV 368

Query: 909  SNSAGKSSHG-ARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNK 964
                G +    A + + D   V     ++++ +   G  V L+C  +   T    W  + 
Sbjct: 369  RRPEGDTFQATAELQLGDAPPVLLYSFIEQTLQP--GPAVSLKCSAAGNPTPQISWTLDG 426

Query: 965  KEISG----MDHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLVVKETIP-- 1017
              +      M  + I   G              D G   CI +++        +  I   
Sbjct: 427  FPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGL 486

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             +IR +        +   L+  +     + + WER G  + P   +   +  G +    +
Sbjct: 487  PYIRLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGREL-PDDIRQRVQPDGSLTISPV 545

Query: 1077 RNTSVHDEGEYSCILRDESC-----TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131
            +  S  D G Y+C  R++       + EVTV+ +PP I      + + +G +      ++
Sbjct: 546  QKNS--DSGVYTCWARNKQGHSARRSGEVTVI-VPPSIEPFAFQEGLAEGMRTRTVCGVS 602

Query: 1132 KGDALVR--WFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYSCEVGNS----K 1184
            +GD  ++  W KDG  +       +T +D     L I       +GEY+C   N     K
Sbjct: 603  RGDPPLKLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIK 662

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYK----KKSVIEDT 1239
             TA+L V+ P   + +  P    V  N    L  +     T  + W K    K    E+ 
Sbjct: 663  YTALLQVKVPP-RWIVE-PVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEV 720

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYEREY 1297
             +      +   +L+++   ED +  Y C   +   T   KV    V   P      R  
Sbjct: 721  RERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSV 780

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSI------DSKSASLTIKKV 1350
             +K+G    L          N  W+ + K  +    + K S+      D  SA L I+ V
Sbjct: 781  MVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTV 840

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
            + TD+G Y  R  N  G+    + + + + P PP       I S S+NI W +P+  G  
Sbjct: 841  DATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIKW-QPKTLGTG 899

Query: 1411 TIIYYVVEYQEID---TTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             +  Y+VE++E D     +W  I VK+       I+NLK  + Y FR  A      S  S
Sbjct: 900  DVTKYIVEFREADPLFVDQWQQIEVKDPPHFNAMIENLKPATRYAFRVIAEGSAGRSAPS 959

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK-----VTWYRDGK 1520
            +     ++I  T+ Q P    P  +++  P    EL  I    P P+     +  Y  G 
Sbjct: 960  Q-----ELIVRTEPQRPA--GPPLSLSARPLSSTEL-LISWVAPLPELRHGDIQGYNVGY 1011

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA----FNDHGEVETSCVVGIQQKPVITIS 1576
            KL ++  T  N                   +A    +    +       G   +P    +
Sbjct: 1012 KLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQT 1071

Query: 1577 NEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNG-------------NKLENDKEYNI 1621
             ED+  +    V    L +  ++    P  I++ NG             + ++  K+   
Sbjct: 1072 MEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVE 1131

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--S 1679
            + K     + +  L++  +    + A    G   V   L  + +   PE P  ++ +  S
Sbjct: 1132 SRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSS 1191

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI--KVADVDRDVETYCIQKLNENCEY 1737
             +S+ I W PP +  G+ +TKY++     +    +  +   +      Y  + L+ + EY
Sbjct: 1192 SQSLYISWLPPNEPNGV-ITKYSLYTRVVNGREELNNEKRSLPSQQAYYEAKGLHPHMEY 1250

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             F V A   VG  E   S      T   +P+              S  +T  P    G  
Sbjct: 1251 QFWVTASTRVG--EGKSSRVSSQITTNRIPARIISFGGPVVRPWRST-VT-LPCTAVGKP 1306

Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
                +K ++                   I  L +     +     N IGT       D++
Sbjct: 1307 KREWFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGT-------DRL 1359

Query: 1858 TIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            T    +  PP+ P  +V S +TS S+ + W +    G +PIT Y + ++   G +    +
Sbjct: 1360 THTLIVQVPPTAPVLYVTS-ATSSSILMHW-KCGFTGNAPITGYTLFYRRANGNTDEMQL 1417

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
            +   S HE  ++ +         +SA+N VG S  +    VR +  +      TA L   
Sbjct: 1418 SRHASSHE--LKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPN 1475

Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT---KTMWMEVGKVDVNTLKFNIRDLSE 2033
                 + + SW     D G PLL + +  R VT      W+ V        +  I +L  
Sbjct: 1476 STSLLVRLHSWP----DNGCPLLYFVLQYRAVTDDPDAEWVLVSNALKPQRRIVINNLQP 1531

Query: 2034 NHTYMIRIYARNEIGLSE 2051
            +  Y +R+ A N  G+S+
Sbjct: 1532 STLYQLRMEAHNVAGISQ 1549



 Score =  103 bits (248), Expect = 4e-20
 Identities = 140/600 (23%), Positives = 227/600 (37%), Gaps = 60/600 (10%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXXXXXXXX 1545
            +  +T    E + L C   G P  ++ W R G++L     +    +              
Sbjct: 492  IPKVTAVSGETLNLKCPVAGYPIEEIHWERGGRELPDDIRQRVQPDGSLTISPVQKNSDS 551

Query: 1546 XXYKCIAFNDHGE-VETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
              Y C A N  G     S  V +   P I      E + +  +      V  V  G PP 
Sbjct: 552  GVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRT---VCGVSRGDPPL 608

Query: 1603 EVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            ++IW K+G+ L +    N+T  ++ +S++ I  L  +HS +YT  A N A        L+
Sbjct: 609  KLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQ 668

Query: 1662 VYDKPSKPEGPV---------IMREISRESV---TIEWKPPLDDGGLELTKYAIEKHEPD 1709
            V   P     PV         IM     + V   +I WK      G +  +Y   +  P 
Sbjct: 669  VKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKAT---GSKSGEYEEVRERPF 725

Query: 1710 N----NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
                 N  + +  V  D E + + + N         + Q  V  S    S       ++ 
Sbjct: 726  TKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSST----SRSVM 781

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR 1825
            V              ++ + I W  S KN  +P  +YK+ +KQE              A 
Sbjct: 782  VKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATP-------DGVSAE 834

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            +Q  +++ T     + R     S  Y +D ++   +   PP  P     +  +SRSV +K
Sbjct: 835  LQIRTVDATDSGPYFCR----ASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIK 890

Query: 1886 WTEPESNGGSPITNYIIEFKTVKG---KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            W +P++ G   +T YI+EF+         W +I           IEN+K      FR+ A
Sbjct: 891  W-QPKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDPPHFNAMIENLKPATRYAFRVIA 949

Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW--GTPEWDGGAPLLG 2000
            E + G S P++   VR E     P+ P   L  R + S  ++ SW    PE   G  + G
Sbjct: 950  EGSAGRSAPSQELIVRTEPQR--PAGPPLSLSARPLSSTELLISWVAPLPELRHG-DIQG 1006

Query: 2001 YNIAIR-----DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEP 2052
            YN+  +     +         G  D    +  +  L++   Y + + A N++G   LSEP
Sbjct: 1007 YNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEP 1066



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 110/478 (23%), Positives = 177/478 (37%), Gaps = 36/478 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM-Y 691
            PP        Q +  G  + L+C     P P I+W   G  +  +    +     +H   
Sbjct: 388  PPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDV 447

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             S + I++V     G Y  +A NR G       L I          I  +  +    GE+
Sbjct: 448  ISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYG-----LPYIRLIPKVTAVSGET 502

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + L   V G P   I W +  + +     +      S+TI   +K  D GVYT  A N +
Sbjct: 503  LNLKCPVAGYPIEEIHWERGGRELPDDIRQRVQPDGSLTISPVQKNSDSGVYTCWARNKQ 562

Query: 812  G-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRN 869
            G  A  S  +TV  P   + EP      FQE   +   T + V  V+R   P  + W ++
Sbjct: 563  GHSARRSGEVTVIVPP--SIEP----FAFQEGLAEGMRT-RTVCGVSRGDPPLKLIWLKD 615

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
             + +            +   L+     S   SG+Y CVA N A +  + A + + V    
Sbjct: 616  GDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRW 675

Query: 930  FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
             V+ +  +   E  + ++L CQ     T S  W       SG ++ E+ +          
Sbjct: 676  IVEPVDAN--VERNRHIMLHCQAQGVPTPSIVWKKATGSKSG-EYEEVRERPFTKLLGNG 732

Query: 988  XXXXXDV-----GVIKCIVKDQ-ETSTMLVVK---ETIPEFIRKLQDFEVKEKDVAILEV 1038
                  V     G   C   +   T    V++    + P F    +   VK+ D A+L+ 
Sbjct: 733  SLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQC 792

Query: 1039 EINSE-TADVVWERDGE-IIKPKKN-----KYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             ++ +   ++VW R G+  + P  N     K +    G   +L IR     D G Y C
Sbjct: 793  AVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSGPYFC 850



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 111/496 (22%), Positives = 189/496 (38%), Gaps = 48/496 (9%)

Query: 646  DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
            DEG+ +L  C     P P+ +W F      P   + V     + +   +L I  V     
Sbjct: 218  DEGAVLL--CVAQGCPSPEYSW-FTHNGAGP---LPVLSGPRVRLLGPILAIEAVTGEDS 271

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            G Y   A N  GEAS  + L + T    P QV      + V  G +      V  N  P 
Sbjct: 272  GVYKCTAGNVGGEASAELRLTVAT----PIQVEISPNVLSVHMGGTAEFRCLVTSNGSPV 327

Query: 766  ----ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
                I W K+ +    LP  S G      ++     ++ G+Y       EG    +   T
Sbjct: 328  GMQNILWYKDGRQ---LP--SSGRVEDTLVVPRVSRENRGMYQCVVRRPEG---DTFQAT 379

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---T 878
             E   +    PP+ +  F E T++    + L      NP P I+W  +   + PS     
Sbjct: 380  AE--LQLGDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPL-PSNGRFM 436

Query: 879  ITQ--NFDGENIELV-ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
            I Q     G+ I  V I++V  E D G+Y C+A N AG+  H AR  +++  + +++ + 
Sbjct: 437  IGQYITVHGDVISHVNISHVMVE-DGGEYACIAENRAGRVQHAAR--LNIYGLPYIRLIP 493

Query: 936  KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
            K      G+T+ L+C  +        W    +E+   D R+ +Q               D
Sbjct: 494  K-VTAVSGETLNLKCPVAGYPIEEIHWERGGRELPD-DIRQRVQPD-GSLTISPVQKNSD 550

Query: 994  VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE------KDVAILEVEINSETADV 1047
             GV  C  ++++  +     E        ++ F  +E      +   +  V        +
Sbjct: 551  SGVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRTVCGVSRGDPPLKL 610

Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VE 1104
            +W +DG+ +             +   L I + S    GEY+C+ ++ +   + T    V+
Sbjct: 611  IWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVK 670

Query: 1105 LPPEIITRLQNQKVNK 1120
            +PP  I    +  V +
Sbjct: 671  VPPRWIVEPVDANVER 686



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 49/229 (21%), Positives = 91/229 (39%), Gaps = 14/229 (6%)

Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
           H  E T             A +   +PP +  +P    V+    I+L C+   +P P I 
Sbjct: 646 HSGEYTCVAKNPAAEIKYTALLQVKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIV 705

Query: 667 W-LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
           W    G +    E +     + +    S+L + +VK+ +EG Y   A N  G   +  V+
Sbjct: 706 WKKATGSKSGEYEEVRERPFTKLLGNGSLL-LQHVKEDREGFYLCQANNGIG-TGIGKVI 763

Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALP 779
           ++K      P      +S++V++G++ +L   V G+    I W ++ K          + 
Sbjct: 764 QLKVNSS--PYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKIS 821

Query: 780 TKSDGDTHSITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            K +     ++    ++     D G Y  +A N  G  +    + V+EP
Sbjct: 822 VKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEP 870



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 40/178 (22%), Positives = 73/178 (41%), Gaps = 9/178 (5%)

Query: 1795 GGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853
            G +PI  Y +  ++  G   +           ++ L   +TYQ  + A+N++GTS   T 
Sbjct: 1394 GNAPITGYTLFYRRANGNTDEMQLSRHASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTI 1453

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
                T G++   P  P +  +    S S+ ++      N G P+  ++++++ V      
Sbjct: 1454 LHVRTQGQS---PGHPASTALLAPNSTSLLVRLHSWPDN-GCPLLYFVLQYRAVTDDPDA 1509

Query: 1914 KIVTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
            + V V  ++       I N++       R+ A N  G+S   E   V L K    P P
Sbjct: 1510 EWVLVSNALKPQRRIVINNLQPSTLYQLRMEAHNVAGIS-QAEFNFVTLTKDGDPPPP 1566



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 4/85 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM----YYDDDNV 565
           P+ +     +    G  V  +C   G P PQI+W      +  +  F +        D +
Sbjct: 389 PVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDVI 448

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAG 590
           + + I  V  ED G + C+A+N AG
Sbjct: 449 SHVNISHVMVEDGGEYACIAENRAG 473



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 515 KLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
           +L PK T   G T+  +C V GYP  +I W R    + P    Q    D ++    +++ 
Sbjct: 490 RLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGREL-PDDIRQRVQPDGSLTISPVQK- 547

Query: 574 FPEDAGTFTCVAKNAAGF-ASSTTELIVEAPLS 605
              D+G +TC A+N  G  A  + E+ V  P S
Sbjct: 548 -NSDSGVYTCWARNKQGHSARRSGEVTVIVPPS 579



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 6/101 (5%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDD----D 563
           +P F    R      G T   +C V G     I W R     + PS ++++        D
Sbjct: 770 SPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPD 829

Query: 564 NV-ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            V A L IR V   D+G + C A N  G      +L V+ P
Sbjct: 830 GVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEP 870


>UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin 1;
            n=1; Rattus norvegicus|Rep: PREDICTED: similar to
            hemicentin 1 - Rattus norvegicus
          Length = 2765

 Score =  142 bits (343), Expect = 1e-31
 Identities = 217/1011 (21%), Positives = 382/1011 (37%), Gaps = 94/1011 (9%)

Query: 696  KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            +I    K +EG Y  +AV+R G   AS  IV+       +PP  + P  ++ V  GE+ I
Sbjct: 388  EIPRASKAEEGVYQCIAVSRAGTGRASAQIVIT------DPPPQLVPGPNVTVSPGETAI 441

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKV-KDEGVYTLKAENS 810
            LS QV+G     +TW ++    +ALP K+        +++     V  D G Y   A N 
Sbjct: 442  LSCQVLGETPYNLTWVRD---WRALPVKTGRVSQLRDLSLEVSSVVPSDGGQYQCVASNP 498

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G+   S  + V EP      P + IN   +    +   +++    +  P P ++W R  
Sbjct: 499  NGLTRASTWLLVREP------PQVSINARSQ-RFSQGVEVRVSCSASGYPKPHVSWSREG 551

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              +     I  +  G    L+I  V  E D+G+Y C A+N  G       VT+       
Sbjct: 552  LALPEDSRIHVDAQG---TLIIQGVAPE-DAGNYSCQAANEVGTDEE--TVTLYYTDPPS 605

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG-RXXXXXXX 987
            V  +     T  G+  +L C  S     +  WY    E+       +  EG R       
Sbjct: 606  VSAINAVVLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVI------LAPEGSRSGTLRIP 659

Query: 988  XXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVK-EKDVAILEVEINSE 1043
                 D G+  C   ++    ++ + ++    P      QD  V+  K V +        
Sbjct: 660  EAQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPPQDVTVELGKSVFLTCRATGRP 719

Query: 1044 TADVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEV 1100
               V W R DG+ ++P +     ++   +  L     S+ D+  Y C  R+      AE 
Sbjct: 720  PPTVTWRRGDGQALEPGRRSRTGQRDSGV--LVFERVSLEDQAPYVCEARNVFGKAQAEA 777

Query: 1101 TVV---ELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLT 1155
             +V     PP+I +     +V +G   +    +  G  L   RW K G  +   N   + 
Sbjct: 778  QLVVTGHAPPQIASSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVR 837

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINF----TLRLPEFI 1206
             DG    L +     +DAG YSC   N      +   ++   +P I          P  +
Sbjct: 838  ADG---SLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRV 894

Query: 1207 LVPANTDAYLTVEIP-DETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
             V A  +A L  E     T  VTW K    ++  T ++ L+S    R +   +    D  
Sbjct: 895  TVKAGEEATLDCEAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLV---QTQVGDSG 951

Query: 1265 EYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             Y C   + A +T +  +  V+ PP++    R  ++  G  + L    +  PQP   W  
Sbjct: 952  LYECTASNPAGATFRRYILGVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFK 1011

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-- 1381
            +  ++          +    S+    V+ +D G+Y     ++ G    ++ + +L+ P  
Sbjct: 1012 DGMVLMG--------EGPPGSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHW 1063

Query: 1382 SPPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQT 1438
                  ++LE  +  ++  +C    + +    I +  V   E ++    ++V N  +   
Sbjct: 1064 GVNETNDLLERVVGENASLLC--PAQGSPKPRITWRRVPSSEALNGRPDVAVLN--EGSL 1119

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
             + ++    S  +   A NEV    AS   +    +      S   E    N++    + 
Sbjct: 1120 FLSSVSLADSGEYECQATNEV--GSASRRVKLVVYVP----PSIREEGRTANMSGLAGQP 1173

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            + L C   G P P+V W +DG+++  A A    +                 Y C A N  
Sbjct: 1174 LTLECDASGFPVPEVVWLKDGQQIPEASAHRFLDGARSLHFPRIQENHSGLYSCQAENQA 1233

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G  +    + +   P +  +    +     G +  +     G+P P+V W K+G  L   
Sbjct: 1234 GRAQRDFNLAVFIPPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPL-LP 1292

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             + +I  +E   V+RI         +Y   A + AG  + +  L ++  P+
Sbjct: 1293 GDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPT 1343



 Score =  140 bits (339), Expect = 4e-31
 Identities = 216/998 (21%), Positives = 371/998 (37%), Gaps = 90/998 (9%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP  S   ++Q   +G ++ + C     P+P ++W  +G  +  D  I V  +       
Sbjct: 513  PPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREGLALPEDSRIHVDAQ------- 565

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I  V     G Y+  A N  G     + L       +PP V      ++   GE  
Sbjct: 566  GTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYY----TDPPSVSAINAVVLTAVGEEA 621

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +L     G P P + W +    V   P   +G       +   + +D G+YT KA N  G
Sbjct: 622  VLLCAASGVPPPRVIWYRGGLEVILAP---EGSRSGTLRIPEAQERDAGLYTCKAVNELG 678

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNE 871
             A     + V        +PP      Q++TV+   ++ L  R T  P P++TW R + +
Sbjct: 679  DASAEIQLLVGY-APRLTDPP------QDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQ 731

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             + P    ++    ++  LV   V  E D   Y C A N  GK+   A++ +       +
Sbjct: 732  ALEPGRR-SRTGQRDSGVLVFERVSLE-DQAPYVCEARNVFGKAQAEAQLVVTGHAPPQI 789

Query: 932  KHLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                      EG+ V L C           +W    + +   +   +  +G         
Sbjct: 790  ASSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADG---SLHLDR 846

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR-KLQDFE---------VKEKDVAILEV 1038
                D G   C+  +   S    V+  +    R K+ D +         VK  + A L+ 
Sbjct: 847  ALQEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDC 906

Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            E   S T  V W +D   + P  N+Y+    G +R   +  T V D G Y C   + +  
Sbjct: 907  EAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLR---LVQTQVGDSGLYECTASNPAGA 963

Query: 1098 A---EVTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQ 1153
                 +  V++PP++    +  KV  G       +        + WFKDG        + 
Sbjct: 964  TFRRYILGVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDG--------MV 1015

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEP---SINFTLRLPEFI 1206
            L  +G    +        D G Y CE  +S  T      L V EP    +N T  L E +
Sbjct: 1016 LMGEGPPGSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERV 1075

Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             V  N       +   +   +TW +  S  E       ++ + + +L +   +  D  EY
Sbjct: 1076 -VGENASLLCPAQGSPKP-RITWRRVPS-SEALNGRPDVAVLNEGSLFLSSVSLADSGEY 1132

Query: 1267 TCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIV 1323
             C   +   +   +V++V + PP I +  R   +    G  +TL  D   FP P   W+ 
Sbjct: 1133 ECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLK 1192

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            + + I +    +  +D  + SL   +++   +G+Y  + EN  G A  + N+ +   PS 
Sbjct: 1193 DGQQIPEASAHR-FLDG-ARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSL 1250

Query: 1384 PG---KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
             G      +L +  + + +   E + +G  T     VE+ + D    +   +    Q   
Sbjct: 1251 LGAGAAQEVLGLAGADVKL---ECQTSGVPT---PQVEWIK-DGQPLLPGDSHILLQEDG 1303

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNE 1497
            Q L+  SS+         V  S A +  + +++     I SP           +T     
Sbjct: 1304 QVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQL----SIHSPPTIWGSNETGEVTVLEGH 1359

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFND 1555
              +L C   G+P P +TWY+DG  L  +++  Y +                 Y C A N 
Sbjct: 1360 TAQLLCEARGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQHSDAGLYTCQASNS 1419

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
             G  + S  + +  +     S+  + +K  + DE + T
Sbjct: 1420 AGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGVYT 1457



 Score =  111 bits (268), Expect = 2e-22
 Identities = 174/782 (22%), Positives = 292/782 (37%), Gaps = 90/782 (11%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            G +V   C+  G P P +TW R     ++P +  +    D  V  LV   V  ED   + 
Sbjct: 706  GKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGV--LVFERVSLEDQAPYV 763

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            C A+N  G A +  +L+V    + H                    +LEG P         
Sbjct: 764  CEARNVFGKAQAEAQLVV----TGHAPPQ-------IASSASVVRVLEGQP--------- 803

Query: 643  QYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
                    + L C ++A  P P+  WL  G  + P    +V  +  +H       +    
Sbjct: 804  --------VSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLH-------LDRAL 848

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQGESVILSAQV 758
            +   G Y+ VA N  G     + L ++   +      Q  +    + V+ GE   L  + 
Sbjct: 849  QEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEA 908

Query: 759  VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             G+P P +TW K+  P+  +  + +  +     L   +V D G+Y   A N  G      
Sbjct: 909  QGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRRY 968

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            ++ V+ P +    P     R  ++   E   +  VA    NP P + W+++  ++     
Sbjct: 969  ILGVQVPPQVQPGP-----RVLKVLAGEALDLNCVAE--GNPQPQLNWFKDGMVLMG--- 1018

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                 +G    +    V +  D+G Y C AS+S+G  +    + +       V       
Sbjct: 1019 -----EGPPGSVHFAAVKTS-DTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLL 1072

Query: 939  ETEEGKTVILEC--QTSHTVSTKWYH--NKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
            E   G+   L C  Q S      W    + + ++G     ++ EG             D 
Sbjct: 1073 ERVVGENASLLCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEG---SLFLSSVSLADS 1129

Query: 995  GVIKCIVKDQETSTMLVVKET--IPEFIR---KLQDFEVKEKDVAILEVEINS-ETADVV 1048
            G  +C   ++  S    VK    +P  IR   +  +          LE + +     +VV
Sbjct: 1130 GEYECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVV 1189

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVEL 1105
            W +DG+ I P+ + + F      R L+      +  G YSC   +++  A+      V +
Sbjct: 1190 WLKDGQQI-PEASAHRF--LDGARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFI 1246

Query: 1106 PPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSE-IQFSNHIQLTIDGKKQ 1161
            PP ++     Q+V     A  ++E  T G     V W KDG   +   +HI L  DG  Q
Sbjct: 1247 PPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDG--Q 1304

Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYL 1216
             L+I    L D G Y C      G       L++   P+I  +    E  ++  +T   L
Sbjct: 1305 VLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLL 1364

Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276
                     D+TWYK  +++  + +  +I     R L + K    D   YTC   ++   
Sbjct: 1365 CEARGMPAPDITWYKDGTLLAPSSE--VIYSKGGRQLQLGKAQHSDAGLYTCQASNSAGI 1422

Query: 1277 TK 1278
            TK
Sbjct: 1423 TK 1424



 Score =  109 bits (262), Expect = 8e-22
 Identities = 189/898 (21%), Positives = 316/898 (35%), Gaps = 113/898 (12%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G T Q  C+  G P P ITW++   ++ PS +  + Y       L + +    DAG +T
Sbjct: 1357 EGHTAQLLCEARGMPAPDITWYKDGTLLAPSSE--VIYSKGG-RQLQLGKAQHSDAGLYT 1413

Query: 583  CVAKNAAGFASSTT---------------ELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            C A N+AG    +T               +LI +A L D G   T               
Sbjct: 1414 CQASNSAGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGV-YTCSATNLAGESKKDVT 1472

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +   +PP     P  + V E + + LEC    +P PDI+W FKG + +  +   + + +D
Sbjct: 1473 LKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDISW-FKGRQPISTQR-HLIVSTD 1530

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIV 746
                  VL I   +    G+Y  VA N  G A+L   L++      PP++ + P     V
Sbjct: 1531 GR----VLHIERAQLSDAGSYRCVATNVVGSAALQYGLRVNV----PPRITLPPSLPGPV 1582

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYT 804
              G    L+    G P P + W K+  PV  +  P         +  +   +  D G Y+
Sbjct: 1583 VLGTPFRLTCNATGTPSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYS 1642

Query: 805  LKAENSEGIAETSAVITVEEPT---------EENAEPPLFINRFQEITVKEKGTIKLVAR 855
              A ++ G      V+ V   +              PP  +     I+V    ++ L  R
Sbjct: 1643 CVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSIAKVPPSILGEELNISVVVNESVALECR 1702

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
                P P + W ++   + P   I  + D   +E+              +C A+    K 
Sbjct: 1703 SHAVPPPVLRWQKDGRPLEPHPGIRLSADKALLEVC-------------RC-AARCPEKP 1748

Query: 916  SHGARVTIDVEKVTF--VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973
            +   RV + V++V      H       + G++        H     W        G    
Sbjct: 1749 NEQGRVDLWVDRVAVWDAGHYTCEAINQAGRS------EKHFNLHVW-GQPLPGDGDSQE 1801

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIPEFIRKLQDFEVK 1029
            +++  GR                 +C        QE    ++V   +      L    V 
Sbjct: 1802 QVLAVGRLLYLGQAQSAQEGTYTCECSNVAGTSSQEQQLEVLVPPQVTGLWEPLTTVSVI 1861

Query: 1030 EKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            +   A L+     +   VV WERDG+ ++ +   +  + + H   L++        G YS
Sbjct: 1862 QDGNATLDCNATGKPLPVVTWERDGQPVRMELGIW-LQNQNH--SLHVDRAQASHAGGYS 1918

Query: 1089 CILRDESCTAE---VTVVELPPEII---TRLQNQKVNKGNKATFEIELTK-GDALVRWFK 1141
            C+  + +  AE      V  PP +      L N         T   E        V+WF+
Sbjct: 1919 CVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEAEGIPPPTVQWFR 1978

Query: 1142 DGSEIQ-FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200
            +G  I        L +    QK+   D   +                +L  EE +     
Sbjct: 1979 EGQPISPGEGTYLLAVPPMFQKMGDADAGFE----------------LLPHEEEAQG--- 2019

Query: 1201 RLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
            R+ E+  V  N  AYL   T  IP    ++TWY++   +   +  +++     R L +  
Sbjct: 2020 RVTEYREVVENNPAYLYCDTNAIPPP--ELTWYREGQPLSAVDGVSVLQG--GRILQLPL 2075

Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQ 1312
               +D   Y+C   +      L  E++   P ++     +   E  +   S V+L     
Sbjct: 2076 VQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPAL 2135

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
              P P   W  N   +      +  +  +   L +   E TDA  Y    EN  G A+
Sbjct: 2136 GNPAPALSWFQNGLPVSPSPRLQ--VLEEGQVLKVSTAEVTDAANYMCVAENQAGSAE 2191



 Score =  108 bits (260), Expect = 1e-21
 Identities = 172/794 (21%), Positives = 291/794 (36%), Gaps = 63/794 (7%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +L G  P  +  P+   V+ G  + L CR    P P + W     + +     S   + D
Sbjct: 686  LLVGYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRD 745

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                  VL    V    +  Y   A N  G+A     L + TG   PPQ+      + V 
Sbjct: 746  ----SGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQL-VVTGH-APPQIASSASVVRVL 799

Query: 748  QGESVILSAQVV-GNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
            +G+ V L+  ++ G P P   W K  +P+        ++DG  H    L+    +D G Y
Sbjct: 800  EGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLHLDRALQ----EDAGRY 855

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            +  A N  G       + V+             +    +TVK      L      +P P 
Sbjct: 856  SCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEAQGSPTPL 915

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +TW ++   + P     +     ++ LV T V    DSG Y+C ASN AG +    R  +
Sbjct: 916  VTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVG---DSGLYECTASNPAGATFR--RYIL 970

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981
             V+    V+   +  +   G+ + L C  + +      W+ +   + G        EG  
Sbjct: 971  GVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMG--------EGPP 1022

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQE-TSTMLVVKETI--PEF-IRKLQDF--EVKEKDVAI 1035
                       D G+  C       T T  +  + +  P + + +  D    V  ++ ++
Sbjct: 1023 GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERVVGENASL 1082

Query: 1036 LEVEINSETADVVWER--DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            L     S    + W R    E +  + +     +      L++ + S+ D GEY C   +
Sbjct: 1083 LCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNE----GSLFLSSVSLADSGEYECQATN 1138

Query: 1094 E--SCTAEV-TVVELPPEIIT--RLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQ 1147
            E  S +  V  VV +PP I    R  N     G   T E + +      V W KDG +I 
Sbjct: 1139 EVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLKDGQQIP 1198

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLP 1203
             ++  +  +DG +  L       + +G YSC+  N    A     L V  P         
Sbjct: 1199 EASAHRF-LDGAR-SLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSLLGAGAA 1256

Query: 1204 EFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262
            + +L  A  D  L  +     T  V W K    +   +   L+ +   + L I      D
Sbjct: 1257 QEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQE-DGQVLRIISSHLGD 1315

Query: 1263 QCEYTCVLLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPND 1319
            +  Y CV            ++ +  PP I   +   E  +  G    LL + +  P P+ 
Sbjct: 1316 EGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDI 1375

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
             W  +  ++         I SK    L + K +++DAG+Y  +  N+ G      N+ + 
Sbjct: 1376 TWYKDGTLLAPSSEV---IYSKGGRQLQLGKAQHSDAGLYTCQASNSAGITKKSTNLEVY 1432

Query: 1379 -DKPSPPGKPNILE 1391
             ++P       ++E
Sbjct: 1433 GERPEGCSSGQLIE 1446



 Score =   99 bits (238), Expect = 7e-19
 Identities = 158/816 (19%), Positives = 295/816 (36%), Gaps = 57/816 (6%)

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SH 954
            S+ + G Y+C+A + AG     A++ I       V     +     G+T IL CQ     
Sbjct: 393  SKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPG--PNVTVSPGETAILSCQVLGET 450

Query: 955  TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTML 1010
              +  W  + + +     R  + + R            D G  +C+  +       ST L
Sbjct: 451  PYNLTWVRDWRALPVKTGR--VSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTRASTWL 508

Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH 1070
            +V+E     I        +  +V +           V W R+G +  P+ ++   + +G 
Sbjct: 509  LVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREG-LALPEDSRIHVDAQG- 566

Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITRLQNQKVNKGNKATFEI 1128
               L I+  +  D G YSC   +E  T E  VT+    P  ++ +    +    +    +
Sbjct: 567  --TLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAINAVVLTAVGEEAVLL 624

Query: 1129 ELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
                G     V W++ G E+     I      +   L+I +    DAG Y+C+  N    
Sbjct: 625  CAASGVPPPRVIWYRGGLEV-----ILAPEGSRSGTLRIPEAQERDAGLYTCKAVNELGD 679

Query: 1187 AILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKF 1242
            A   ++   + +  RL   P+ + V      +LT          VTW +      +  + 
Sbjct: 680  ASAEIQL-LVGYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRR 738

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRI 1299
            +         L+  + + +DQ  Y C   +     + + ++V     PP+I       R+
Sbjct: 739  SRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRV 798

Query: 1300 KRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
              G  V+L  V     P P   W+   + +          D    SL + +    DAG Y
Sbjct: 799  LEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADG---SLHLDRALQEDAGRY 855

Query: 1359 KLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
                 N  G  H DVE+ V          KP I   DS + +         G    +   
Sbjct: 856  SCVATNVAGSQHRDVELVVQ--------AKPRIKINDSQATDAPLRVTVKAGEEATLDCE 907

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE----YYK 1472
             +        W    +     T+   L ++ S R     V +  + + + +      + +
Sbjct: 908  AQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRR 967

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
             I   ++  P V+   + +     E ++L C+  G PQP++ W++DG  L          
Sbjct: 968  YILGVQVP-PQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMGEGPP---- 1022

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                           Y C A +  G       + + + P   ++  +   +  VG+   +
Sbjct: 1023 GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERVVGENASL 1082

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                +G P P + W +  +    +   ++    + S+  +  +  + S +Y  +A+N  G
Sbjct: 1083 LCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLF-LSSVSLADSGEYECQATNEVG 1141

Query: 1653 TSSVEVTLKVYDKPS-KPEGPVI-MREISRESVTIE 1686
            ++S  V L VY  PS + EG    M  ++ + +T+E
Sbjct: 1142 SASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLE 1177



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 105/490 (21%), Positives = 200/490 (40%), Gaps = 64/490 (13%)

Query: 489  NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
            ++K+ +L V   P+ ++    P    ++R      G      C+ +  P P +TWF+   
Sbjct: 2228 DQKMVQLSVLVPPSFKQAPGGPQEAVQVRA-----GDKATLNCETDSLPEPAVTWFKDQQ 2282

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608
             +   Q  Q          L I +    D G ++C   N AG A+ T EL ++  +  + 
Sbjct: 2283 PLALGQRIQGLQGGQK---LEILDSQVSDKGVYSCKVSNTAGEATRTFELNIQGSVWGYS 2339

Query: 609  SEMTVXXXXXXXXXXXXADILEG-----------------IPPTFSKKPKAQY--VDEGS 649
            +   V               L                   +PP        Q   V EG 
Sbjct: 2340 TCQLVNPVALSAESYPMLASLPPASACPCCFRAFTMAPVTVPPQIQNSGMTQEHNVLEGQ 2399

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            ++ L C     P PDIAWL +G  +  D+++   +    ++  S L +  ++    G YT
Sbjct: 2400 EVRLGCEAEGQPPPDIAWLKEGGPL--DQHVGPHLR--FYLDGSTLVLKGLRAADSGAYT 2455

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
             VA N  GE +    + +        Q  +   +++ R GE V +   V G+P   ++W 
Sbjct: 2456 CVAHNPAGEDARLHTVNVLVPPTIKQQASD-TGTLVSRTGELVTMMCPVQGSPPIHVSWL 2514

Query: 770  KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT-- 826
            K+  P+ AL  ++       T+ +   ++ D GV+T  A +  G+A  +  + V++ +  
Sbjct: 2515 KDGLPL-ALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSVL 2573

Query: 827  EENAE-------------------PPLF-INRFQEITVKEKGT-IKLVARVTRNPVPSIT 865
            E++                     PP+     FQ   +  +G+ + L      +P+P ++
Sbjct: 2574 EDSPSVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSPLPLVS 2633

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W ++ E + P +++ Q   G  ++L   ++    DSG Y C+A++ AG++    ++T+  
Sbjct: 2634 WMKDGEPLLP-QSLEQ---GPGLKLEAVSIG---DSGTYSCMAASEAGEARRHFQLTVME 2686

Query: 926  EKVTFVKHLQ 935
              +T   HL+
Sbjct: 2687 LSLTPGAHLE 2696



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 92/422 (21%), Positives = 163/422 (38%), Gaps = 33/422 (7%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G+ V+ ECQ  G P PQ+ W +    + P     +  +D  V  ++   +   D G + C
Sbjct: 1264 GADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDGQVLRIISSHL--GDEGRYQC 1321

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTFSKKPKA 642
            VA + AG  +   +L + +P +  GS  T                  G+P P  +     
Sbjct: 1322 VAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKDG 1381

Query: 643  QYVDEGSDILL-----ECRLVAIPEPDIAWLF----KGEEIVPDENISVAIESDMHMYCS 693
              +   S+++      + +L      D A L+         +  ++ ++ +  +    CS
Sbjct: 1382 TLLAPSSEVIYSKGGRQLQLGKAQHSD-AGLYTCQASNSAGITKKSTNLEVYGERPEGCS 1440

Query: 694  VLKITNVKKFQ-EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              ++      + EG YT  A N  GE+   + LK+      PP +     +  V +  SV
Sbjct: 1441 SGQLIEKADLRDEGVYTCSATNLAGESKKDVTLKVLV----PPNIEPGPVNKAVLENASV 1496

Query: 753  ILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L     G P P I+W K  +P+   + L   +DG    +  ++  ++ D G Y   A N
Sbjct: 1497 TLECLASGVPPPDISWFKGRQPISTQRHLIVSTDG---RVLHIERAQLSDAGSYRCVATN 1553

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G A     + V  P      P L         V      +L    T  P P + W ++
Sbjct: 1554 VVGSAALQYGLRVNVPPRITLPPSL------PGPVVLGTPFRLTCNATGTPSPMLLWLKD 1607

Query: 870  NEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
               +SP  T   + F G  + L + +  +  D+G Y CVA ++ G+      + +  E +
Sbjct: 1608 GNPVSPEGTPGLKVFPGGQV-LTVASARAS-DAGGYSCVAVSAVGEDRRDIVLQVHSESL 1665

Query: 929  TF 930
             +
Sbjct: 1666 AW 1667



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 7/177 (3%)

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFN 1554
            D++L C   GVP P+V W +DG+ L    +     E+                Y+C+AF+
Sbjct: 1266 DVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFS 1325

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
              G+      + I   P I  SNE  +     G    +     G+P P++ WYK+G  L 
Sbjct: 1326 PAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKDGTLLA 1385

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
               E  +   +    +++ + + S +  YT +ASN+AG +     L+VY +  +PEG
Sbjct: 1386 PSSE--VIYSKGGRQLQLGKAQHSDAGLYTCQASNSAGITKKSTNLEVYGE--RPEG 1438



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 71/338 (21%), Positives = 139/338 (41%), Gaps = 24/338 (7%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP--PGKPNI-LEIDSS 1395
            +S ++S  I +    + G+Y+    +  G       + I D P    PG PN+ +    +
Sbjct: 381  ESGNSSWEIPRASKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPG-PNVTVSPGET 439

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
            +I  C    E   N T   +V +++ +       V  +      + ++  +   +++  A
Sbjct: 440  AILSCQVLGETPYNLT---WVRDWRALPVKTG-RVSQLRDLSLEVSSVVPSDGGQYQCVA 495

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
             N   ++ AS     + +++E     P V    ++       ++ ++C   G P+P V+W
Sbjct: 496  SNPNGLTRAST----WLLVREP----PQVSINARSQRFSQGVEVRVSCSASGYPKPHVSW 547

Query: 1516 YRDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
             R+G  L + ++   + +               Y C A N+ G  E +  +     P ++
Sbjct: 548  SREGLALPEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVS 607

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
              N  +     VG+E ++     G+PPP VIWY+ G ++    E       ++  +RI E
Sbjct: 608  AINAVVLTA--VGEEAVLLCAASGVPPPRVIWYRGGLEVILAPE-----GSRSGTLRIPE 660

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
             +   +  YT +A N  G +S E+ L V   P   + P
Sbjct: 661  AQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPP 698



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 47/179 (26%), Positives = 75/179 (41%), Gaps = 6/179 (3%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V E +   L C   AIP P++ W  +G+ +   + +SV           +L++  V+   
Sbjct: 2027 VVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGG------RILQLPLVQAED 2080

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y+  A N  GE  L   L + T    P    E ++ + V    +V L    +GNP P
Sbjct: 2081 AGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAP 2140

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
             ++W +N  PV   P     +   +  +   +V D   Y   AEN  G AE    + V+
Sbjct: 2141 ALSWFQNGLPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQ 2199



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 69/304 (22%), Positives = 116/304 (38%), Gaps = 19/304 (6%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C     P P++TW+R+   +  + D         +  L +  V  EDAG ++C A N  G
Sbjct: 2037 CDTNAIPPPELTWYREGQPLS-AVDGVSVLQGGRILQLPL--VQAEDAGRYSCKASNEVG 2093

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
                  EL+V  P    G   T             A  LE  P   +  P   +   G  
Sbjct: 2094 EDWLHYELLVLTPPVIPGD--TQELVEEVTVNASSAVSLE-CPALGNPAPALSWFQNGLP 2150

Query: 651  ILLECRLVAIPEPDIAWLFKGEE------IVPDENISVAIESDMHMYCS---VLKITNVK 701
            +    RL  + E  +  +   E       +   EN + + E    +       L++   +
Sbjct: 2151 VSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQGTHTLRLARAQ 2210

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
                GTY   A+N  G     + L +            P +++ VR G+   L+ +    
Sbjct: 2211 PADSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNCETDSL 2270

Query: 762  PRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            P P +TW K+ +P+ AL  +  G      + IL   +V D+GVY+ K  N+ G A  +  
Sbjct: 2271 PEPAVTWFKDQQPL-ALGQRIQGLQGGQKLEIL-DSQVSDKGVYSCKVSNTAGEATRTFE 2328

Query: 820  ITVE 823
            + ++
Sbjct: 2329 LNIQ 2332



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 36/186 (19%), Positives = 73/186 (39%), Gaps = 3/186 (1%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXX 1539
            P +E    N     N  + L C+  GVP P ++W++  + + T +      +        
Sbjct: 1479 PNIEPGPVNKAVLENASVTLECLASGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIER 1538

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y+C+A N  G       + +   P IT+    +     +G  + +T    G 
Sbjct: 1539 AQLSDAGSYRCVATNVVGSAALQYGLRVNVPPRITLP-PSLPGPVVLGTPFRLTCNATGT 1597

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P ++W K+GN +  +    +       V+ +   + S +  Y+  A +  G    ++ 
Sbjct: 1598 PSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGEDRRDIV 1657

Query: 1660 LKVYDK 1665
            L+V+ +
Sbjct: 1658 LQVHSE 1663



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 53/217 (24%), Positives = 87/217 (40%), Gaps = 23/217 (10%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            S V  EC   G P P ++WF+    + PS   Q+  ++  V  +   EV   DA  + CV
Sbjct: 2126 SAVSLECPALGNPAPALSWFQNGLPVSPSPRLQV-LEEGQVLKVSTAEV--TDAANYMCV 2182

Query: 585  AKNAAGFASSTTELIVE---------APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT 635
            A+N AG A     L V+         A  +D G+ +                +   +PP+
Sbjct: 2183 AENQAGSAEKLFTLRVQGTHTLRLARAQPADSGTYL-CEALNPAGRDQKMVQLSVLVPPS 2241

Query: 636  FSKKP----KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            F + P    +A  V  G    L C   ++PEP + W    + +   + I   ++      
Sbjct: 2242 FKQAPGGPQEAVQVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQ-GLQGGQK-- 2298

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
               L+I + +   +G Y+    N  GEA+    L I+
Sbjct: 2299 ---LEILDSQVSDKGVYSCKVSNTAGEATRTFELNIQ 2332



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
           R +    G  V+  C   GYP+P ++W R+   +   +D +++ D     TL+I+ V PE
Sbjct: 521 RSQRFSQGVEVRVSCSASGYPKPHVSWSREGLALP--EDSRIHVDAQG--TLIIQGVAPE 576

Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           DAG ++C A N  G    T  L    P S
Sbjct: 577 DAGNYSCQAANEVGTDEETVTLYYTDPPS 605



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 39/171 (22%), Positives = 70/171 (40%), Gaps = 6/171 (3%)

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            N    L C    +P P++TWYR+G+ L      +  +                 Y C A 
Sbjct: 2030 NNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGGRILQLPLVQAEDAGRYSCKAS 2089

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611
            N+ GE      + +   PVI    +++ ++  V     V+      G P P + W++NG 
Sbjct: 2090 NEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPALSWFQNG- 2148

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             L       +   E+  V+++   + + ++ Y   A N AG++    TL+V
Sbjct: 2149 -LPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRV 2198



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 43/176 (24%), Positives = 70/176 (39%), Gaps = 8/176 (4%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIA 1552
            +++ L C   G P P + W ++G  L          Y +                Y C+A
Sbjct: 2399 QEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYTCVA 2458

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             N  GE      V +   P I     D      + G+   +   ++G PP  V W K+G 
Sbjct: 2459 HNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWLKDGL 2518

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
             L   +   +    +T  +RI +++ + S  +T  AS+ AG ++   TL V DK S
Sbjct: 2519 PLALSQRTLLHNSGRT--LRISQVQLADSGVFTCVASSPAGVANRNFTLLV-DKGS 2571



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 3/131 (2%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXX 1543
            +PL  ++   + +  L C   G P P VTW RDG+ ++     +                
Sbjct: 1853 EPLTTVSVIQDGNATLDCNATGKPLPVVTWERDGQPVRMELGIWLQNQNHSLHVDRAQAS 1912

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPP 1602
                Y C+A N  G  E    + +   P +T  ++ +      +     +    EGIPPP
Sbjct: 1913 HAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEAEGIPPP 1972

Query: 1603 EVIWYKNGNKL 1613
             V W++ G  +
Sbjct: 1973 TVQWFREGQPI 1983



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 3/77 (3%)

Query: 1117 KVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
            +V  G+KAT   E     +  V WFKD   +     IQ    G  QKL+I D  + D G 
Sbjct: 2254 QVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGG--QKLEILDSQVSDKGV 2311

Query: 1176 YSCEVGNSKCTAILTVE 1192
            YSC+V N+   A  T E
Sbjct: 2312 YSCKVSNTAGEATRTFE 2328



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 1575 ISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            I N  + Q+H V  G E  +    EG PPP++ W K G  L+     ++      S + +
Sbjct: 2384 IQNSGMTQEHNVLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVL 2443

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            K L+ + S  YT  A N AG  +   T+ V   P+
Sbjct: 2444 KGLRAADSGAYTCVAHNPAGEDARLHTVNVLVPPT 2478



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 7/138 (5%)

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
            TH++ + + +   D G Y  +A N  G  +    ++V  P      P       + + V+
Sbjct: 2201 THTLRLARAQPA-DSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPG---GPQEAVQVR 2256

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
                  L       P P++TW+++ + ++  + I     G+ +E++ + V    D G Y 
Sbjct: 2257 AGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQKLEILDSQVS---DKGVYS 2313

Query: 906  CVASNSAGKSSHGARVTI 923
            C  SN+AG+++    + I
Sbjct: 2314 CKVSNTAGEATRTFELNI 2331



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 12/97 (12%)

Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
           T  G      C   G P P++ W+R     I+ P        +     TL I E    DA
Sbjct: 615 TAVGEEAVLLCAASGVPPPRVIWYRGGLEVILAP--------EGSRSGTLRIPEAQERDA 666

Query: 579 GTFTCVAKNAAGFASSTTELIV-EAP-LSDHGSEMTV 613
           G +TC A N  G AS+  +L+V  AP L+D   ++TV
Sbjct: 667 GLYTCKAVNELGDASAEIQLLVGYAPRLTDPPQDVTV 703



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           +G  V   C +  G P P+  W +    + P     +  D     +L +     EDAG +
Sbjct: 800 EGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRAD----GSLHLDRALQEDAGRY 855

Query: 582 TCVAKNAAGFASSTTELIVEA 602
           +CVA N AG      EL+V+A
Sbjct: 856 SCVATNVAGSQHRDVELVVQA 876



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T    CQV G     +TW R    + P +  ++    D   +L +  V P D G + C
Sbjct: 437 GETAILSCQVLGETPYNLTWVRDWRAL-PVKTGRVSQLRD--LSLEVSSVVPSDGGQYQC 493

Query: 584 VAKNAAGFASSTTELIVEAP 603
           VA N  G   ++T L+V  P
Sbjct: 494 VASNPNGLTRASTWLLVREP 513



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 19/201 (9%)

Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
            EV E + A L  + N+    ++ W R+G+ +          + G I +L +      D G
Sbjct: 2026 EVVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDG-VSVLQGGRILQLPL--VQAEDAG 2082

Query: 1086 EYSCILRDE--SCTAEVTVVELPPEIITR-----LQNQKVNKGNKATFEIELTKGDA-LV 1137
             YSC   +E         ++ L P +I       ++   VN  +  + E       A  +
Sbjct: 2083 RYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAL 2142

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPS 1195
             WF++G  +  S  +Q+  +G  Q LK+   ++ DA  Y C   N   +A  + T+    
Sbjct: 2143 SWFQNGLPVSPSPRLQVLEEG--QVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQG 2200

Query: 1196 INFTLRLPEFILVPANTDAYL 1216
             + TLRL      PA++  YL
Sbjct: 2201 TH-TLRLAR--AQPADSGTYL 2218



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 20/44 (45%), Positives = 25/44 (56%)

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            YT  A+N AG S  +VTLKV   P+   GPV    +   SVT+E
Sbjct: 1456 YTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKAVLENASVTLE 1499



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
            L N+T   +  + L C   G+P P V W+R+G+ +   + TY
Sbjct: 1949 LTNVTATLHGSLTLLCEAEGIPPPTVQWFREGQPISPGEGTY 1990


>UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 578

 Score =  141 bits (342), Expect = 2e-31
 Identities = 151/578 (26%), Positives = 247/578 (42%), Gaps = 65/578 (11%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMH 689
            G  P+ S +     V EG+DI L C++   P+P + W +KG+ +V  D+ IS   +    
Sbjct: 12   GDAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTW-YKGDALVKLDDRISAHFDGRF- 69

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
               S L I    K  EG Y     N  G+A   + L ++    +P  V E   +  V +G
Sbjct: 70   ---SRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERG 126

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            E V    +V G P+P + W +   PV      +DG   SI+       + E +Y+L    
Sbjct: 127  E-VRFEVRVTGFPKPRVEWYRG--PVHL----TDGGRFSIS-------EKEDMYSL---- 168

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
                       TV +   +++     +    + TV +     LV RV+  P P+ITW+R+
Sbjct: 169  -----------TVRDLKRDDSGTYKLV---AQNTVGKCDKYTLVCRVSGKPKPTITWFRD 214

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV- 928
            N  +     +  +++G    L +  +    D+G YKC A+NS G +S  A VTI  +   
Sbjct: 215  NTPVHTDNRVVASYEGSVSALELKEMKLS-DAGLYKCTATNSQGSTSSSAEVTIKRKDAI 273

Query: 929  -TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
             TFV  L K  E  E   + L+ +       + ++Y +   I   +  +I+++G      
Sbjct: 274  PTFVVGL-KETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLI 332

Query: 986  XXXXXXXDVGVIKCIVKD---QETSTMLV-VKE--------TIPEFIRKLQDFEVKEKDV 1033
                   D G  KC++ +    ETS  ++ V+E          PEF+RK++D    E + 
Sbjct: 333  ITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQ 392

Query: 1034 AILEVEINSETADVV-WERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
               E+ I      +V W R    IK   +      +   +  L I      D G Y C+ 
Sbjct: 393  VWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVA 452

Query: 1092 RDES--CTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
             +++   TA    +V    + PE    ++  +V  G +AT  +E+  K    V W+KDG 
Sbjct: 453  SNDAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGK 512

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
             ++ S +IQL   G    ++I     +D G Y CE  N
Sbjct: 513  VLRESKNIQLKSIGDTYSIRIVRTAPEDVGTYMCEATN 550



 Score =  120 bits (288), Expect = 6e-25
 Identities = 99/403 (24%), Positives = 170/403 (42%), Gaps = 48/403 (11%)

Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
           C+V G P+P ITWFR    +         Y+  +V+ L ++E+   DAG + C A N+ G
Sbjct: 199 CRVSGKPKPTITWFRDNTPVHTDNRVVASYEG-SVSALELKEMKLSDAGLYKCTATNSQG 257

Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
             SS+             +E+T+                    PTF    K     E SD
Sbjct: 258 STSSS-------------AEVTIKRKDAI--------------PTFVVGLKETEGLESSD 290

Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
           + L+ ++   P P + +    + IV  E   +  + D    CS++ ITN++    GTY  
Sbjct: 291 MRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDR---CSLI-ITNLRPEDAGTYKC 346

Query: 711 VAVNREGEASLPIVLKIKTGEKEP-----PQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
           V  N  G  +   V++++  E  P     P+ +  ++ +   + E V     + G PRP 
Sbjct: 347 VITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPI 406

Query: 766 ITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
           + W +    +K      +    + D +S+ ++   + +D G Y   A N  G  +T+A++
Sbjct: 407 VEWYRGTTRIKDGGRFTISESEENDMYSL-VIDEARTEDSGPYKCVASNDAG--KTTALL 463

Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            ++    E    P F    + I VK          +   P P +TWY++ +++  S+ I 
Sbjct: 464 NLD--VNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQ 521

Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
               G+   + I     E D G Y C A+N AG +S    +TI
Sbjct: 522 LKSIGDTYSIRIVRTAPE-DVGTYMCEATNKAGLASRKFDITI 563



 Score =  113 bits (272), Expect = 5e-23
 Identities = 129/577 (22%), Positives = 236/577 (40%), Gaps = 56/577 (9%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            + P   ++   + V E   I LV +V+ NP P++TWY+ + ++   + I+ +FDG    L
Sbjct: 13   DAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRL 72

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--FVKHLQKSYETEEGKTVIL 948
             I     + D G Y C   N  GK+     +T+    V    V  ++ + E E G+ V  
Sbjct: 73   SIQKATKD-DEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGE-VRF 130

Query: 949  ECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006
            E + +     +  WY       G  H  +   GR             V  +K   +D   
Sbjct: 131  EVRVTGFPKPRVEWYR------GPVH--LTDGGRFSISEKEDMYSLTVRDLK---RDDSG 179

Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFE 1066
            +  LV + T+ +           +K   +  V        + W RD   +    N+    
Sbjct: 180  TYKLVAQNTVGKC----------DKYTLVCRVS-GKPKPTITWFRDNTPVHTD-NRVVAS 227

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVV--ELPPEIITRLQNQKVNK 1120
              G +  L ++   + D G Y C   +     S +AEVT+   +  P  +  L+  +  +
Sbjct: 228  YEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLE 287

Query: 1121 GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
             +    ++++       V ++KD   I  S   ++  DG +  L I +   +DAG Y C 
Sbjct: 288  SSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCV 347

Query: 1180 VGN----SKCTAILTVEEP--SINFTLRLPEFILVPANTDAYLT----VEIPDETLD--- 1226
            + N        A++ V+E   +  F ++ PEF+    +  A  T     EIP +      
Sbjct: 348  ITNLLGVETSEAVIRVQEREHAPRFDVK-PEFLRKVEDVTALETEQVWFEIPIQGYPRPI 406

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVE 1282
            V WY+  + I+D  +FT+    +    +L+I +   +D   Y CV  +   K+T  L ++
Sbjct: 407  VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLD 466

Query: 1283 VVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V E    P+     +   +K G + T  ++ +  P+P   W  + K++++ K+ +     
Sbjct: 467  VNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIG 526

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
             + S+ I +    D G Y     N  G A  + ++TI
Sbjct: 527  DTYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITI 563



 Score =  110 bits (264), Expect = 5e-22
 Identities = 87/329 (26%), Positives = 149/329 (45%), Gaps = 37/329 (11%)

Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
           T + +   P FV  L+     + S ++ + ++ G+PRP + +++   +I  S+  ++  D
Sbjct: 266 TIKRKDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILED 325

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
            D   +L+I  + PEDAGT+ CV  N  G    T+E ++     +H     V        
Sbjct: 326 GDR-CSLIITNLRPEDAGTYKCVITNLLGV--ETSEAVIRVQEREHAPRFDVK------- 375

Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-- 679
                       P F +K +     E   +  E  +   P P + W ++G   + D    
Sbjct: 376 ------------PEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEW-YRGTTRIKDGGRF 422

Query: 680 -ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQV 737
            IS + E+DM+     L I   +    G Y  VA N  G+ +   +L +   EK   P+ 
Sbjct: 423 TISESEENDMYS----LVIDEARTEDSGPYKCVASNDAGKTTA--LLNLDVNEKVVQPEF 476

Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794
            + +K + V+ GE    S ++ G P+P +TW K+ K +   K +  KS GDT+SI I++ 
Sbjct: 477 DKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVRT 536

Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVE 823
              +D G Y  +A N  G+A     IT++
Sbjct: 537 AP-EDVGTYMCEATNKAGLASRKFDITIK 564



 Score =  105 bits (253), Expect = 1e-20
 Identities = 118/577 (20%), Positives = 224/577 (38%), Gaps = 49/577 (8%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P + ++L   +V +GN      +++      V W+K  + ++  + I    DG+  +L I
Sbjct: 15   PSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRLSI 74

Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
                 DD G Y C+V N    A   VE       ++ P+ +    + +     E+  E  
Sbjct: 75   QKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVK-PQIVGEIKDAEEVERGEVRFEVR 133

Query: 1226 -------DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
                    V WY+    + D  +F++       +L +R    DD   Y  V   A++T  
Sbjct: 134  VTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLV---AQNT-- 188

Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
                                + +    TL+      P+P   W  ++  +        S 
Sbjct: 189  --------------------VGKCDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASY 228

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP----GKPNILEIDS 1394
            +   ++L +K+++ +DAG+YK    N+ G       VTI  K + P    G      ++S
Sbjct: 229  EGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLES 288

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            S + +   +       T+ +Y      +D+     +++  +    I NL+   +  ++  
Sbjct: 289  SDMRLDV-KIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCV 347

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
              N + +  +       +     +    P   + ++++T    E +       G P+P V
Sbjct: 348  ITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIV 407

Query: 1514 TWYR------DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             WYR      DG +   +++   +                YKC+A ND G+      + +
Sbjct: 408  EWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 467

Query: 1568 QQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
             +K V    ++++K  + K G+E   +  I+G P P+V WYK+G  L   K   + +   
Sbjct: 468  NEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGD 527

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSS--VEVTLK 1661
            T  IRI          Y  EA+N AG +S   ++T+K
Sbjct: 528  TYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITIK 564



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 107/462 (23%), Positives = 189/462 (40%), Gaps = 50/462 (10%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE 1282
            VTWYK  ++++  ++ +   D +   L I+K T+DD+  Y C + +    A S  +L V 
Sbjct: 46   VTWYKGDALVKLDDRISAHFDGRFSRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVR 105

Query: 1283 VVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
                 P+IV + +    ++RG +V   V    FP+P  EW      +        S    
Sbjct: 106  KRNVKPQIVGEIKDAEEVERG-EVRFEVRVTGFPKPRVEWYRGPVHLTDGGRFSISEKED 164

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
              SLT++ ++  D+G YKL  +N  G  D     T++ + S   KP I     ++     
Sbjct: 165  MYSLTVRDLKRDDSGTYKLVAQNTVGKCD---KYTLVCRVSGKPKPTITWFRDNT----- 216

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              P +T N  +  Y      ++  E                +K + +  ++  A N    
Sbjct: 217  --PVHTDNRVVASYEGSVSALELKE----------------MKLSDAGLYKCTATN---- 254

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
            S  S ++     IK  K   PT    LK      + D+ L    GG P+P V +Y+D   
Sbjct: 255  SQGSTSSSAEVTIKR-KDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDL 313

Query: 1522 LKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVIT 1574
            +  ++        +R               YKC+  N  G   +  V+ +Q++   P   
Sbjct: 314  IVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFD 373

Query: 1575 ISNEDIKQKHKVG----DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV- 1629
            +  E +++   V     ++      I+G P P V WY+   ++++   + I+  E+  + 
Sbjct: 374  VKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMY 433

Query: 1630 -IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
             + I E +   S  Y   ASN AG ++  + L V +K  +PE
Sbjct: 434  SLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKVVQPE 475



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 48/195 (24%), Positives = 81/195 (41%), Gaps = 7/195 (3%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXX 1537
            +P++   L  +      DI+L C     P+P VTWY+    +K      A ++ R     
Sbjct: 14   APSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRLS 73

Query: 1538 XXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG-DEWLVTAV 1595
                       Y C   N+ G+  +   + ++++ V      +IK   +V   E      
Sbjct: 74   IQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVRFEVR 133

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-TS 1654
            + G P P V WY+    L +   ++I+ KE    + +++LKR  S  Y + A NT G   
Sbjct: 134  VTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLVAQNTVGKCD 193

Query: 1655 SVEVTLKVYDKPSKP 1669
               +  +V  KP KP
Sbjct: 194  KYTLVCRVSGKP-KP 207



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 61/303 (20%), Positives = 117/303 (38%), Gaps = 14/303 (4%)

Query: 1465 SETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            SE  + Y + +++ K       K +   T    +   L C   G P+P +TW+RD   + 
Sbjct: 160  SEKEDMYSLTVRDLKRDDSGTYKLVAQNTVGKCDKYTLVCRVSGKPKPTITWFRDNTPVH 219

Query: 1524 T---AKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
            T     A+YE                  YKC A N  G   +S  V I++K  I      
Sbjct: 220  TDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVG 279

Query: 1580 IKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638
            +K+   +   +  +   I G P P V +YK+ + + + + + I        + I  L+  
Sbjct: 280  LKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPE 339

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE---GPVIMREI----SRESVTIEWKPPL 1691
             +  Y    +N  G  + E  ++V ++   P     P  +R++    + E+  + ++ P+
Sbjct: 340  DAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPI 399

Query: 1692 DDGGLELTK-YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
                  + + Y       D  R+      + D+ +  I +        ++ +A N  G +
Sbjct: 400  QGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKT 459

Query: 1751 EAL 1753
             AL
Sbjct: 460  TAL 462



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 1/105 (0%)

Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
           V E+  +    + P F+ K+      +   V FE  ++GYPRP + W+R T  IK    F
Sbjct: 363 VQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRF 422

Query: 557 QMYYDDDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +   ++N + +LVI E   ED+G + CVA N AG  ++   L V
Sbjct: 423 TISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 467



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 29/115 (25%), Positives = 61/115 (53%), Gaps = 5/115 (4%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           DE  Y   +Q +L +   K+ +    T  ++++ P  V +++     +   V+FE +V G
Sbjct: 81  DEGIYICDVQNELGKAFSKVEL----TVRKRNVKPQIVGEIKDAEEVERGEVRFEVRVTG 136

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
           +P+P++ W+R    +     F +   +D + +L +R++  +D+GT+  VA+N  G
Sbjct: 137 FPKPRVEWYRGPVHLTDGGRFSISEKED-MYSLTVRDLKRDDSGTYKLVAQNTVG 190



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP    +L P    +G+ +   C+V   P+P +TW++  A++K       ++ D   + L
Sbjct: 14  APSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHF-DGRFSRL 72

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            I++   +D G + C  +N  G A S  EL V
Sbjct: 73  SIQKATKDDEGIYICDVQNELGKAFSKVELTV 104


>UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome
            shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 17
            SCAF14747, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1748

 Score =  140 bits (339), Expect = 4e-31
 Identities = 96/364 (26%), Positives = 167/364 (45%), Gaps = 23/364 (6%)

Query: 478  NNYTQYLQKKLNEKIDKLPVFEKPTSEEQS-------MAPIFVEKLRPKHTPDGSTVQFE 530
            +++ Q L  ++  ++++ PV E     +         + PIF +KL+     +G  V F 
Sbjct: 1388 SSFEQRLMSEIEFRLERTPVEESDEEVQHDDVPTGKCIVPIFDKKLKNFKAMEGVPVTFS 1447

Query: 531  CQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
            C++ G P P++ WF+    I+K +  ++   D D    L I     +D G +T +A N  
Sbjct: 1448 CKIVGIPVPKVYWFKDGKQILKKNVHYKKIRDGDGTCALHIESTTSDDDGNYTVMAANPQ 1507

Query: 590  GFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEG----IPPTFSKKPKAQY 644
            G  S +  LIV+  P         +            A+  E       P F + P    
Sbjct: 1508 GRISCSGHLIVQTGPPRPRCRHFILRGERRVQSCVREAEGEEAQERFFKPHFLQAPGDML 1567

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKF 703
              EG    L+C++  +P P++ WL  G+ I PD    + + E+ +H     L I  + + 
Sbjct: 1568 AHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHS----LVIDPLTQK 1623

Query: 704  QEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
              GTYT +A N+ G++S  + LK+ +   K PPQ +E L++M + +G  V L  +VVG P
Sbjct: 1624 DAGTYTCIASNKAGQSSFSLELKVVEKAMKYPPQFLEKLQNMGIPEGTPVRLECRVVGMP 1683

Query: 763  RPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             P I W K+N  +    + +    D   +   +++P +  D G YT+ A+N  GI   + 
Sbjct: 1684 PPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSCTC 1743

Query: 819  VITV 822
             + +
Sbjct: 1744 RLDI 1747



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 10/110 (9%)

Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DDDNVA 566
           E L+  +   G  V  EC+V G P P++ W+R  + ++ S DF++         + + + 
Sbjct: 792 ENLQDVYASCGQLVALECRVRGVPSPRVVWYRDESQMEDSPDFRILQKKPRSPAESEEIC 851

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV---EAPLSDHGSEMTV 613
           TLVI EVFPED+G FTC A N  G  SST  L V   +AP  ++GS+  V
Sbjct: 852 TLVIAEVFPEDSGMFTCTASNKFGTVSSTAALRVKVNDAPKHENGSQAVV 901



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 50/157 (31%), Positives = 80/157 (50%), Gaps = 9/157 (5%)

Query: 461 HLTEEKGWVPAQYLMDENNYTQYLQKKLN-----EKIDKLPVFEKP-TSEEQSMAPIFVE 514
           H TE++   P    + +   TQ LQ   N     ++ +     E P  +E +   P F++
Sbjct: 579 HQTEDRP-EPGTGQLQDCGITQELQPNCNVQDAGKETEGCTPTETPYPTEPECEPPQFIQ 637

Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
           KLR +   +GS VQ +C V G P P++ WF +   ++ S D Q+  ++  + +L+I E F
Sbjct: 638 KLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQI-LNNGELHSLIISEAF 696

Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610
            ED G ++C A N  G  S++ E+ VE A  SD   E
Sbjct: 697 EEDTGRYSCFASNVCGTDSTSAEIYVEGASSSDSEGE 733



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 55/195 (28%), Positives = 87/195 (44%), Gaps = 10/195 (5%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSI 789
            P  ++    M+  +G+   L  +V G P P + W  N KP+       +  + +G  HS+
Sbjct: 1557 PHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENG-VHSL 1615

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
             ++ P   KD G YT  A N  G +  S  + V E   +   PP F+ + Q + + E   
Sbjct: 1616 -VIDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKY--PPQFLEKLQNMGIPEGTP 1672

Query: 850  IKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
            ++L  RV   P P I W ++N+ I +  E IT   D      ++     + D+G Y   A
Sbjct: 1673 VRLECRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSA 1732

Query: 909  SNSAGKSSHGARVTI 923
             N AG  S   R+ I
Sbjct: 1733 KNEAGIVSCTCRLDI 1747



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 3/124 (2%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            D   YT     K  +    L +  K   +     P F+EKL+    P+G+ V+ EC+V G
Sbjct: 1624 DAGTYTCIASNKAGQSSFSLEL--KVVEKAMKYPPQFLEKLQNMGIPEGTPVRLECRVVG 1681

Query: 536  YPRPQITWFRQT-AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
             P P I W +   +I    +   M  D      L+I+    +DAG +T  AKN AG  S 
Sbjct: 1682 MPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSC 1741

Query: 595  TTEL 598
            T  L
Sbjct: 1742 TCRL 1745



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 66/262 (25%), Positives = 107/262 (40%), Gaps = 39/262 (14%)

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKS-- 782
            + TG+   P   + LK+    +G  V  S ++VG P P + W K+ K +  K +  K   
Sbjct: 1419 VPTGKCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYKKIR 1478

Query: 783  DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE------------------- 823
            DGD      ++     D+G YT+ A N +G    S  + V+                   
Sbjct: 1479 DGDGTCALHIESTTSDDDGNYTVMAANPQGRISCSGHLIVQTGPPRPRCRHFILRGERRV 1538

Query: 824  -----EPTEENAEPPLFINRF----QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
                 E   E A+   F   F     ++   E    +L  +V+  P P + W  N + I 
Sbjct: 1539 QSCVREAEGEEAQERFFKPHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIY 1598

Query: 875  PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-----T 929
            P            +  ++ +  ++ D+G Y C+ASN AG+SS    + + VEK       
Sbjct: 1599 PDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQSSFSLELKV-VEKAMKYPPQ 1657

Query: 930  FVKHLQKSYETEEGKTVILECQ 951
            F++ LQ +    EG  V LEC+
Sbjct: 1658 FLEKLQ-NMGIPEGTPVRLECR 1678



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 1/100 (1%)

Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
           PTE   EPP FI + +   + E   ++L   V   P P + W+   + +  S  I    +
Sbjct: 625 PTEPECEPPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNN 684

Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           GE   L+I+    E D+G Y C ASN  G  S  A + ++
Sbjct: 685 GELHSLIISEAFEE-DTGRYSCFASNVCGTDSTSAEIYVE 723



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 4/104 (3%)

Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTH 787
           E EPPQ I+ L+S  + +G  V L   V G P P + W    K ++  P     ++G+ H
Sbjct: 629 ECEPPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELH 688

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           S+ I+     +D G Y+  A N  G   TSA I VE  +  ++E
Sbjct: 689 SL-IISEAFEEDTGRYSCFASNVCGTDSTSAEIYVEGASSSDSE 731



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 12/174 (6%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXX-XXXXXXXXYKCIAFND 1555
            L C   G+P P++ W  +GK     L       EN                 Y CIA N 
Sbjct: 1576 LDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNK 1635

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE----GIPPPEVIWYKNGN 1611
             G+   S  + + +K  +    + +++   +G        +E    G+PPP + W K+ +
Sbjct: 1636 AGQSSFSLELKVVEK-AMKYPPQFLEKLQNMGIPEGTPVRLECRVVGMPPPVIFWKKDND 1694

Query: 1612 KLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
             + N KE    T++ T  +   I+  ++  +  YT+ A N AG  S    L +Y
Sbjct: 1695 SIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSCTCRLDIY 1748



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 23/76 (30%), Positives = 37/76 (48%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G +  +  ++ G+PPPEV W+  G +LEN  +  I    +   + I E     + +Y+  
Sbjct: 647  GSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELHSLIISEAFEEDTGRYSCF 706

Query: 1647 ASNTAGTSSVEVTLKV 1662
            ASN  GT S    + V
Sbjct: 707  ASNVCGTDSTSAEIYV 722



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 3/79 (3%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            PP+ I +L+++++ +G+K   +  + +G     VRWF +G E++ S  IQ+  +G+   L
Sbjct: 632  PPQFIQKLRSREIAEGSKVQLDC-IVRGLPPPEVRWFCEGKELENSPDIQILNNGELHSL 690

Query: 1164 KIYDCDLDDAGEYSCEVGN 1182
             I +   +D G YSC   N
Sbjct: 691  IISEAFEEDTGRYSCFASN 709



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G+P PE++W  NG  +  D  + +  +E     + I  L +  +  YT  ASN AG S
Sbjct: 1580 VSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQS 1639

Query: 1655 SVEVTLKVYDKPSK 1668
            S  + LKV +K  K
Sbjct: 1640 SFSLELKVVEKAMK 1653



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 16/191 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D    E  +  L+ +++   A +++W  +G+ I P        +   +  L 
Sbjct: 1557 PHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLV 1616

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y+CI  ++    S + E+ VVE     PP+ + +LQN  + +G     E
Sbjct: 1617 IDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKYPPQFLEKLQNMGIPEGTPVRLE 1676

Query: 1128 IELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQK-LKIYDCDLDDAGEYSC----EV 1180
              +      ++ W KD   I      I +T D      L I     DDAG Y+     E 
Sbjct: 1677 CRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEA 1736

Query: 1181 GNSKCTAILTV 1191
            G   CT  L +
Sbjct: 1737 GIVSCTCRLDI 1747



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 4/82 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F +K +++ + EGS + L+C +  +P P++ W  +G+E+    +I +    ++H   
Sbjct: 632 PPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELHS-- 689

Query: 693 SVLKITNVKKFQEGTYTVVAVN 714
             L I+   +   G Y+  A N
Sbjct: 690 --LIISEAFEEDTGRYSCFASN 709



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 10/86 (11%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTK--------EKTSVIRIKELKRSHSSKYTIEA 1647
            + G+P P V+WY++ +++E+  ++ I  K        E+   + I E+    S  +T  A
Sbjct: 811  VRGVPSPRVVWYRDESQMEDSPDFRILQKKPRSPAESEEICTLVIAEVFPEDSGMFTCTA 870

Query: 1648 SNTAGT--SSVEVTLKVYDKPSKPEG 1671
            SN  GT  S+  + +KV D P    G
Sbjct: 871  SNKFGTVSSTAALRVKVNDAPKHENG 896



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 6/115 (5%)

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            +  +  +D T         K  +  Q L +   +R     V E D     E  ++  V  
Sbjct: 1367 ITHHSSVDLTSCFPFFQEYKVSSFEQRLMSEIEFRLERTPVEESD-----EEVQHDDV-P 1420

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530
              K   P  +K LKN        +  +C   G+P PKV W++DGK++      Y+
Sbjct: 1421 TGKCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYK 1475



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%)

Query: 1570 KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEY-NITTKEK 1626
            K ++ I ++ +K  K   G     +  I GIP P+V W+K+G + L+ +  Y  I   + 
Sbjct: 1423 KCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYKKIRDGDG 1482

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
            T  + I+         YT+ A+N  G  S    L V   P +P
Sbjct: 1483 TCALHIESTTSDDDGNYTVMAANPQGRISCSGHLIVQTGPPRP 1525



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 8/143 (5%)

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE----F 1286
            K +  D     L+ +    +L+I   T+ D   YTC+  +   +S+  L+++VVE    +
Sbjct: 1595 KPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKY 1654

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH--TKPSIDSKSAS 1344
            PP+ ++  +   I  G+ V L       P P   W  ++  I   K   T     +    
Sbjct: 1655 PPQFLEKLQNMGIPEGTPVRLECRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVC 1714

Query: 1345 LTIKKVENTDAGIYKLRLENNCG 1367
            L I+     DAG Y +  +N  G
Sbjct: 1715 LLIQPTRKDDAGWYTVSAKNEAG 1737



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 17/134 (12%)

Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
           T  ++     +S+P +L + T    P    E L+ +    G+ V L  +V G P P + W
Sbjct: 766 TATSLPLNAVSSVPPILTLPTQTSHP----ENLQDVYASCGQLVALECRVRGVPSPRVVW 821

Query: 769 CKNNKPVKALP--------TKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818
            ++   ++  P         +S  ++  I  L   +V  +D G++T  A N  G   ++A
Sbjct: 822 YRDESQMEDSPDFRILQKKPRSPAESEEICTLVIAEVFPEDSGMFTCTASNKFGTVSSTA 881

Query: 819 VITV---EEPTEEN 829
            + V   + P  EN
Sbjct: 882 ALRVKVNDAPKHEN 895


>UniRef50_UPI0000F2E010 Cluster: PREDICTED: similar to chondroitin
            polymerizing factor,; n=1; Monodelphis domestica|Rep:
            PREDICTED: similar to chondroitin polymerizing factor, -
            Monodelphis domestica
          Length = 1692

 Score =  139 bits (337), Expect = 7e-31
 Identities = 110/425 (25%), Positives = 185/425 (43%), Gaps = 12/425 (2%)

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +TW  N   I+P   I  + +G N  L +       DSG    V + + G  S  AR+ +
Sbjct: 856  LTWLLNGTAITPCNRIETSQNGPNHTLTLRCCQIS-DSGT---VTAQTEGSEST-ARLHV 910

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKEISGMDHREIIQEGR 980
               ++ F++ LQ +  TEEG+ + +E +TS         W    K +       ++Q+GR
Sbjct: 911  REAELLFLRRLQDA-RTEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDGR 969

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                        D G+  C      T   L+V+    +    L+D  V E   A  ++E+
Sbjct: 970  VHRLIIHKVMVSDQGIYCCKSHHDRTQARLLVRPEQLKVRHPLEDVVVTEGGSATFQLEL 1029

Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
            +       W R G  ++P +N      +GH   L +    + D G  S       C A +
Sbjct: 1030 SQSGVTGEWARGGVRLEPGRN-CQISAQGHNHCLVLSGLGLADTGTVSFTTDTLRCAARL 1088

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
             V E+P  I+  LQ+ +V +G+ ATFE EL++  A + W KDG E+  S  +++   G +
Sbjct: 1089 EVKEIPLAIVKGLQDLEVIEGDSATFECELSRTQADLTWDKDGQELSPSPRLRIQALGSR 1148

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAI-LTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
            + L++  C   DAG YSC VGNS+ +A  LTV +  ++    L   +       A     
Sbjct: 1149 RLLQLRCCGPKDAGTYSCCVGNSQASAARLTVRKKEVSVLQELKP-VKAREGDGATFKCT 1207

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +    +  +W     V+    +  +  +    +L + +   +D  E       AKS+T L
Sbjct: 1208 VSQPGIPGSWQLGGRVLRPGGRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQAKSSTHL 1267

Query: 1280 KVEVV 1284
            +VEV+
Sbjct: 1268 EVEVL 1272



 Score =  137 bits (332), Expect = 3e-30
 Identities = 147/639 (23%), Positives = 253/639 (39%), Gaps = 37/639 (5%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            DI L  R+    EP+  W+     +V D N+ +  E    M    L I        G YT
Sbjct: 753  DIRLAGRVRQFLEPE--WI----SVVEDGNLELRSEGTRRM----LFIRAAHPSHAGNYT 802

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
              A       +L     ++  E    +++  L  + +++G+      +V       +TW 
Sbjct: 803  CQAGCEPAAPTL--TFPVQVSEIPQAKLVLELTPLTIQEGDDATFRCEVFPADAE-LTWL 859

Query: 770  KNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
             N     P   + T  +G  H++T L+  ++ D G  T + E SE  A     + V E  
Sbjct: 860  LNGTAITPCNRIETSQNGPNHTLT-LRCCQISDSGTVTAQTEGSESTAR----LHVRE-- 912

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI-TWYRNNEIISPSETITQNFDG 885
               AE  LF+ R Q+   +E   + +    +R     I TW R  + +      +   DG
Sbjct: 913  ---AEL-LFLRRLQDARTEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDG 968

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
                L+I  V    D G Y C + +   +    AR+ +  E++  V+H  +     EG +
Sbjct: 969  RVHRLIIHKVMVS-DQGIYCCKSHHDRTQ----ARLLVRPEQLK-VRHPLEDVVVTEGGS 1022

Query: 946  VILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
               + + S + V+ +W      +    + +I  +G             D G +       
Sbjct: 1023 ATFQLELSQSGVTGEWARGGVRLEPGRNCQISAQGHNHCLVLSGLGLADTGTVSFTTDTL 1082

Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064
              +  L VKE     ++ LQD EV E D A  E E++   AD+ W++DG+ + P   +  
Sbjct: 1083 RCAARLEVKEIPLAIVKGLQDLEVIEGDSATFECELSRTQADLTWDKDGQELSPSP-RLR 1141

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123
             +  G  R L +R     D G YSC +   ++  A +TV +    ++  L+  K  +G+ 
Sbjct: 1142 IQALGSRRLLQLRCCGPKDAGTYSCCVGNSQASAARLTVRKKEVSVLQELKPVKAREGDG 1201

Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ATF+  +++      W   G  ++    +++  +G    L + +   +D+GE   + G +
Sbjct: 1202 ATFKCTVSQPGIPGSWQLGGRVLRPGGRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQA 1261

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
            K +  L VE   +    R P    V A   A L V +      V W      +    K+ 
Sbjct: 1262 KSSTHLEVEVLPLQICRRPPREKTVLAGRRAALEVTVSRGGGHVRWLLGGVDLPPGPKYE 1321

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
              S     +LII      D+  Y C   +  + T L VE
Sbjct: 1322 FRSHGVTHSLIIHNVQPTDEGTYCCQAGEDSANTNLLVE 1360



 Score =  114 bits (274), Expect = 3e-23
 Identities = 128/590 (21%), Positives = 224/590 (37%), Gaps = 43/590 (7%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            + EG D    C +    + ++ WL  G  I P   I  +     H     L+   +    
Sbjct: 837  IQEGDDATFRCEVFPA-DAELTWLLNGTAITPCNRIETSQNGPNHTL--TLRCCQIS--D 891

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNP 762
             GT T      E  A L +        +     +  L+     +G+ + +  +   VG  
Sbjct: 892  SGTVTAQTEGSESTARLHV-------REAELLFLRRLQDARTEEGQELSMEVETSRVGG- 943

Query: 763  RPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            +  +TW +  KP+   P  S   DG  H + I K   V D+G+Y  K+ +      T A 
Sbjct: 944  QGIVTWLRGGKPLPEDPRFSVVQDGRVHRLIIHKVM-VSDQGIYCCKSHHDR----TQAR 998

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            + V  P +     PL     +++ V E G+      ++++ V    W R    + P    
Sbjct: 999  LLVR-PEQLKVRHPL-----EDVVVTEGGSATFQLELSQSGVTG-EWARGGVRLEPGRNC 1051

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
              +  G N  LV++ +    D+G      S +       AR+ +    +  VK LQ   E
Sbjct: 1052 QISAQGHNHCLVLSGLGLA-DTG----TVSFTTDTLRCAARLEVKEIPLAIVKGLQ-DLE 1105

Query: 940  TEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
              EG +   EC+ S T     W  + +E+S      I   G             D G   
Sbjct: 1106 VIEGDSATFECELSRTQADLTWDKDGQELSPSPRLRIQALGSRRLLQLRCCGPKDAGTYS 1165

Query: 999  CIV-KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
            C V   Q ++  L V++     +++L+  + +E D A  +  ++       W+  G +++
Sbjct: 1166 CCVGNSQASAARLTVRKKEVSVLQELKPVKAREGDGATFKCTVSQPGIPGSWQLGGRVLR 1225

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
            P   +    + G++  L +      D GE          +  + V  LP +I  R   +K
Sbjct: 1226 PG-GRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQAKSSTHLEVEVLPLQICRRPPREK 1284

Query: 1118 -VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
             V  G +A  E+ +++G   VRW   G ++      +    G    L I++    D G Y
Sbjct: 1285 TVLAGRRAALEVTVSRGGGHVRWLLGGVDLPPGPKYEFRSHGVTHSLIIHNVQPTDEGTY 1344

Query: 1177 SCEVGNSKCTAILTVEE--PSIN-FTLRLPEFILVPANTDAYLTVEIPDE 1223
             C+ G       L VE+  PS +  T     ++ VP   D  L++ +  +
Sbjct: 1345 CCQAGEDSANTNLLVEKEGPSPSCLTFCSVCWLAVPQAPDPVLSISLASD 1394



 Score =  109 bits (261), Expect = 1e-21
 Identities = 132/551 (23%), Positives = 217/551 (39%), Gaps = 57/551 (10%)

Query: 831  EPPLFINRFQE---ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887
            EPP+ I   Q+   +  +    + L   +++   P + WY++  +   SET+     G +
Sbjct: 393  EPPVKILFPQDQVCVAAESSERVVLSCELSQAGAP-VHWYKDGMVAKESETLLLERKGLH 451

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTV 946
              L++     + D G + C     AG       VTI    V  V+   + + T    + V
Sbjct: 452  CHLILPAAQPQ-DGGKFVC----KAGDDQAVFHVTITEPPVQIVQPQDEMFLTAVTSERV 506

Query: 947  ILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
            +L CQ S   +   WY N  E+    +  +  EG             D G   C  +D  
Sbjct: 507  VLMCQVSQPRALVGWYKNGMEVEESKYLVLESEGLQHRLVLPSVRLQDGGEFVCSTRDDS 566

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVK--EKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063
                L V E   + +    +  V     +  +L  E++   A V W +DG  ++ +    
Sbjct: 567  AFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAGAPVRWYKDGLEVE-ENEAL 625

Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR-----LQNQKV 1118
              E  G   +L +      D GE+ C   D+S    V+V  +PPE I R     LQ Q  
Sbjct: 626  VLESEGPYHRLVLPAAQPQDGGEFVCDAGDDSAFFIVSVT-VPPERIVRPAARFLQLQFR 684

Query: 1119 NKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            + G +     E+    A V W+KDG E++ S  ++L  +G  + L +      DAGEY C
Sbjct: 685  SPG-RVELRCEVAPVGARVCWYKDGLEVEASEDLKLGAEGPIRTLTLPQARPQDAGEYVC 743

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
            E             + +++F +RL   +                + L+  W    SV+ED
Sbjct: 744  E-----------TRDEAVSFDIRLAGRV---------------RQFLEPEWI---SVVED 774

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCV--LLDAKSTTKLKVEVVEFP-PKIVDYER 1295
                 L S+  +R L IR         YTC      A  T    V+V E P  K+V    
Sbjct: 775  -GNLELRSEGTRRMLFIRAAHPSHAGNYTCQAGCEPAAPTLTFPVQVSEIPQAKLVLELT 833

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
               I+ G D T     + FP   +  W++N   I  C   + S +  + +LT++  + +D
Sbjct: 834  PLTIQEGDDATFRC--EVFPADAELTWLLNGTAITPCNRIETSQNGPNHTLTLRCCQISD 891

Query: 1355 AGIYKLRLENN 1365
            +G    + E +
Sbjct: 892  SGTVTAQTEGS 902



 Score =  108 bits (260), Expect = 1e-21
 Identities = 98/440 (22%), Positives = 176/440 (40%), Gaps = 17/440 (3%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            I  K    + L+  ++R   P + WY++   I  S+ +    +G    LVI     +   
Sbjct: 316  IEAKSLEQVVLLCELSRAGAP-VHWYKDGLEIEESQAMVLENEGLQCRLVIPAAQPQ-HG 373

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVTFV-KHLQKSYETEEGKTVILECQTSHT-VSTK 959
            G++ C     AG+ S    VTI    V  +    Q     E  + V+L C+ S       
Sbjct: 374  GEFVC----KAGEDSAFFMVTIKEPPVKILFPQDQVCVAAESSERVVLSCELSQAGAPVH 429

Query: 960  WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019
            WY +       +   + ++G             D G   C   D +    + + E   + 
Sbjct: 430  WYKDGMVAKESETLLLERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFHVTITEPPVQI 489

Query: 1020 IRKLQDFEVKE--KDVAILEVEINSETADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYI 1076
            ++   +  +     +  +L  +++   A V W ++G  ++ +++KY   E  G   +L +
Sbjct: 490  VQPQDEMFLTAVTSERVVLMCQVSQPRALVGWYKNG--MEVEESKYLVLESEGLQHRLVL 547

Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN--KGNKATFEIELTKGD 1134
             +  + D GE+ C  RD+S    +TV E P +I+       V      +     EL++  
Sbjct: 548  PSVRLQDGGEFVCSTRDDSAFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAG 607

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
            A VRW+KDG E++ +  + L  +G   +L +      D GE+ C+ G+     I++V  P
Sbjct: 608  APVRWYKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVCDAGDDSAFFIVSVTVP 667

Query: 1195 SINFTLRLPEFILVPANTDAY--LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
                      F+ +   +     L  E+      V WYK    +E +E   L ++   RT
Sbjct: 668  PERIVRPAARFLQLQFRSPGRVELRCEVAPVGARVCWYKDGLEVEASEDLKLGAEGPIRT 727

Query: 1253 LIIRKCTEDDQCEYTCVLLD 1272
            L + +    D  EY C   D
Sbjct: 728  LTLPQARPQDAGEYVCETRD 747



 Score =  103 bits (246), Expect = 7e-20
 Identities = 83/360 (23%), Positives = 142/360 (39%), Gaps = 12/360 (3%)

Query: 937  SYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
            S E +  + V+L C+ S       WY +  EI       +  EG               G
Sbjct: 315  SIEAKSLEQVVLLCELSRAGAPVHWYKDGLEIEESQAMVLENEGLQCRLVIPAAQPQHGG 374

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQD---FEVKEKDVAILEVEINSETADVVWERD 1052
               C   +     M+ +KE  P  I   QD      +  +  +L  E++   A V W +D
Sbjct: 375  EFVCKAGEDSAFFMVTIKEP-PVKILFPQDQVCVAAESSERVVLSCELSQAGAPVHWYKD 433

Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112
            G + K  +     E++G    L +      D G++ C   D+     VT+ E P +I+  
Sbjct: 434  GMVAKESETLL-LERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFHVTITEPPVQIVQP 492

Query: 1113 LQNQKVNK--GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170
                 +      +     ++++  ALV W+K+G E++ S ++ L  +G + +L +    L
Sbjct: 493  QDEMFLTAVTSERVVLMCQVSQPRALVGWYKNGMEVEESKYLVLESEGLQHRLVLPSVRL 552

Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD-AYLTVEIPDETLDVTW 1229
             D GE+ C   +      LTV EP +       E  +   +++   LT E+      V W
Sbjct: 553  QDGGEFVCSTRDDSAFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAGAPVRW 612

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
            YK    +E+ E   L S+     L++      D  E+ C   DA   +   +  V  PP+
Sbjct: 613  YKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVC---DAGDDSAFFIVSVTVPPE 669



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 153/721 (21%), Positives = 274/721 (38%), Gaps = 71/721 (9%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C L     P + W   G EI  +E+ ++ +E++  + C ++ I   +    G +  
Sbjct: 324  VVLLCELSRAGAP-VHWYKDGLEI--EESQAMVLENE-GLQCRLV-IPAAQPQHGGEF-- 376

Query: 711  VAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIV--RQGESVILSAQVVGNPRPTIT 767
              V + GE S   ++ IK    EPP +++ P   + V     E V+LS ++     P + 
Sbjct: 377  --VCKAGEDSAFFMVTIK----EPPVKILFPQDQVCVAAESSERVVLSCELSQAGAP-VH 429

Query: 768  WCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            W K+    K   T        H   IL   + +D G +  KA + + +      +T+ EP
Sbjct: 430  WYKDGMVAKESETLLLERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFH----VTITEP 485

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
              +  +P      F      E+  + L+ +V++ P   + WY+N   +  S+ +    +G
Sbjct: 486  PVQIVQPQ--DEMFLTAVTSER--VVLMCQVSQ-PRALVGWYKNGMEVEESKYLVLESEG 540

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
                LV+ +V  + D G++ C  S     +     VT    K+ F +  + S      + 
Sbjct: 541  LQHRLVLPSVRLQ-DGGEFVC--STRDDSAFFTLTVTEPPVKILFPRD-EVSVAAVSSER 596

Query: 946  VILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
            V+L C+ S      +WY +  E+   +   +  EG             D G   C   D 
Sbjct: 597  VVLTCELSRAGAPVRWYKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVCDAGDD 656

Query: 1005 ETSTMLVVKETIP--EFIRKLQDF---EVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
              S   +V  T+P    +R    F   + +      L  E+    A V W +DG  ++  
Sbjct: 657  --SAFFIVSVTVPPERIVRPAARFLQLQFRSPGRVELRCEVAPVGARVCWYKDGLEVEAS 714

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
            ++       G IR L +      D GEY C  RDE+ + +   + L   +   L+ + ++
Sbjct: 715  ED-LKLGAEGPIRTLTLPQARPQDAGEYVCETRDEAVSFD---IRLAGRVRQFLEPEWIS 770

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
                   E+  ++G   + + +        N               Y C    AG   CE
Sbjct: 771  VVEDGNLELR-SEGTRRMLFIRAAHPSHAGN---------------YTC---QAG---CE 808

Query: 1180 VGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
                  T  + V E P     L L   + +    DA    E+     ++TW    + I  
Sbjct: 809  PAAPTLTFPVQVSEIPQAKLVLELTP-LTIQEGDDATFRCEVFPADAELTWLLNGTAITP 867

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298
              +     +    TL +R C   D    T     ++ST +L V   E     +   ++ R
Sbjct: 868  CNRIETSQNGPNHTLTLRCCQISDSGTVTAQTEGSESTARLHVREAEL--LFLRRLQDAR 925

Query: 1299 IKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
             + G ++++ V+  +   Q    W+   K + +        D +   L I KV  +D GI
Sbjct: 926  TEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDGRVHRLIIHKVMVSDQGI 985

Query: 1358 Y 1358
            Y
Sbjct: 986  Y 986



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1100 VTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158
            V  V +   I  RL  +  V +G  A   +E+     L RW +DG E+  S  I  T   
Sbjct: 8    VAAVAVKGPITRRLPRKLDVLEGENAVLSVEVRGAKVLGRWTRDGQELPASPRIIQTSSN 67

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
                L +      DAG  +  +G+S  ++ L V+
Sbjct: 68   HTHTLVLVGVTRQDAGVVTFSLGSSHTSSRLRVK 101


>UniRef50_P52179 Cluster: Myomesin-1; n=19; Euteleostomi|Rep:
            Myomesin-1 - Homo sapiens (Human)
          Length = 1451

 Score =  139 bits (337), Expect = 7e-31
 Identities = 105/402 (26%), Positives = 170/402 (42%), Gaps = 18/402 (4%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727
            P   + + E +R  V + WKPP    G E   Y +EK E     W +V  ++      + 
Sbjct: 503  PPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 561

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L E   Y FRV   N  G  E  E+ E  V+   LD+P            D  SV +
Sbjct: 562  LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT-SVVV 620

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI--QKLSINTTYQFRIYARN 1843
            +W   E      ++ Y +E    G  KW+          R     L    +Y FR+ A N
Sbjct: 621  SW--EESKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVN 678

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
              G S      + I +   + PPS P +    ES   S+ L W +P+  GG+ IT Y + 
Sbjct: 679  AAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVN 738

Query: 1904 FKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVR 1958
            ++     V GK W +          + I N+KE     F+++A N  G+  P+  S+  +
Sbjct: 739  YREVIDGVPGK-WREANVKAVREEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 797

Query: 1959 LEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK-TMWMEV 2016
             E+    VP PP + L+   V  + ++  W  P   G  P+ GY + +++  K   W  +
Sbjct: 798  CEEWTIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGL 856

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
             +  +  +   +R L E  +Y+ R+ A N+ G+ +P +   P
Sbjct: 857  NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 898



 Score =  124 bits (299), Expect = 3e-26
 Identities = 114/498 (22%), Positives = 184/498 (36%), Gaps = 42/498 (8%)

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            PE+ WY+NG  L   K        + + +    L +     YTI              + 
Sbjct: 303  PEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 362

Query: 1662 VYDKPSKPEG----PVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            V D  ++ EG    P+ ++  E +++ + I WK P  DGG  +  Y I+K E   + W +
Sbjct: 363  VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 422

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF------SEALESEPIVIKTALDVPSX 1769
              D       + +  L E   Y+FRV A N +G       SEA+ +     K  L  P  
Sbjct: 423  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLS 482

Query: 1770 XXXXXXXXXIDNES--------------------VYITWFPSEKNGGSPIIDYKVEIKQE 1809
                      +  S                    V ++W P  + G   I+ +  + +  
Sbjct: 483  TLDWTVIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 542

Query: 1810 GKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
             + W+         +    +  L+   +Y FR+   N  G   P  + +   +G  L  P
Sbjct: 543  TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 602

Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
              P   + S +T  SV + W E  S     +  Y IE        W          H   
Sbjct: 603  KAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFT 660

Query: 1927 IENIKEKDEIIFRISAENTVGVS-LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
               +      IFR+ A N  G+S    +S+++ ++     PSPP     +     ++V+ 
Sbjct: 661  CHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVL- 719

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTM---WMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
             W  P+  GGA + GY +  R+V   +   W E     V    + I +L EN  Y  ++ 
Sbjct: 720  GWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVA 779

Query: 2043 ARNEIGLSEPLESDEPFK 2060
            A N  GL  P    E FK
Sbjct: 780  AMNMAGLGAPSAVSECFK 797



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 58/238 (24%), Positives = 94/238 (39%), Gaps = 13/238 (5%)

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSKPEGPVIMREISR 1680
            KT       L    S  + + A N AG S     S  + +K    P  P   +   E  R
Sbjct: 655  KTHRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFR 714

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDN---NRWIKVADVDRDVETYCIQKLNENCEY 1737
            +S+ + WK P   GG E+T Y +   E  +    +W +        E Y I  L EN  Y
Sbjct: 715  DSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVY 774

Query: 1738 MFRVIAQNPVGF-SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
             F+V A N  G  + +  SE    +                 +  +S+ + W P   +G 
Sbjct: 775  QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 834

Query: 1797 SPIIDYKVEIKQEGK--KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLP 1850
            +P+  Y V++K++ K  +W+            +++ L    +Y FR+ A N+ G   P
Sbjct: 835  TPVTGYFVDLKEKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 892



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 73/313 (23%), Positives = 121/313 (38%), Gaps = 35/313 (11%)

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQ 1836
            + + + I+W     +GGSPI+ Y ++  + G   W          AR  +  L    +Y 
Sbjct: 386  NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 445

Query: 1837 FRIYARNEIGTSLPYTSDDKI--------------------TIGKTLTPPSQ------PR 1870
            FR+ A N++G   P    + +                    T+  T   PS+      P 
Sbjct: 446  FRVRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWTVIVTEEEPSEGIVPGPPT 505

Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHEHCIEN 1929
            +  V+E+T   V L W  P   G   I  Y +E      ++W ++ T +        + +
Sbjct: 506  DLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFD 564

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988
            + E     FR+   N+ GV  P+E+  V  +     +P  P   +  R   +++V+ SW 
Sbjct: 565  LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVV-SW- 622

Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              E      L+GY I         W       V T +F    L    +Y+ R+ A N  G
Sbjct: 623  -EESKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAG 681

Query: 2049 LSEPLESDEPFKV 2061
            LSE  +  E  +V
Sbjct: 682  LSEYSQDSEAIEV 694



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 25/243 (10%)

Query: 1284 VEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            + F  K  V + RE   +  G  V +  + + F QP   W  N   +   K  +     +
Sbjct: 269  IHFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEIRWYRNGVPLSPSKWVQTLWSGE 327

Query: 1342 SASLTIKKVENTDAGIYKLRL------ENNCGHADV-EMNVTILDKPSPPGKPNILEIDS 1394
             A+LT   +   D G+Y +R+      E    +  V + +  I   P+ P     LE + 
Sbjct: 328  RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 387

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452
              I I W +P   G S I+ Y ++  E+ T  W    +  +   +  +  L    SY FR
Sbjct: 388  DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 447

Query: 1453 AYAVNEVDISDASETTEYYKVI---KETKIQSP----------TVEKPLKNITTEPNEDI 1499
              AVN++ I   S  +E    +   ++ +++SP          T E+P + I   P  D+
Sbjct: 448  VRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWTVIVTEEEPSEGIVPGPPTDL 507

Query: 1500 ELT 1502
             +T
Sbjct: 508  SVT 510



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTT--EW--ISVKNITK 1435
            PSPP     LE    S+ + W +P+ TG + I  Y V Y+E ID    +W   +VK + +
Sbjct: 701  PSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVRE 760

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
                I NLK N  Y+F+  A+N   +   S  +E +K  +E  I  P     LK
Sbjct: 761  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLK 813



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 47/233 (20%), Positives = 86/233 (36%), Gaps = 14/233 (6%)

Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           L + +++   +    +E+  + AP F+ K R     +   V+  C + G+P P++TW++ 
Sbjct: 118 LRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKN 177

Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
              I    +   Y  +    + TL I     ED   +   A N  G  S+   ++V+   
Sbjct: 178 QVPINVHANPGKYIIESRYGMHTLEINACDFEDTAQYRASAMNVKGELSAYASVVVKRYK 237

Query: 605 SDHGSEMTVXXXXXXXXXXXXA--DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE 662
            +                               F  K    +  EG  + L CR+V  PE
Sbjct: 238 GEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPE 297

Query: 663 -----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
                P+I W   G  + P + +      +     + L  +++ K  EG YT+
Sbjct: 298 IKHFQPEIRWYRNGVPLSPSKWVQTLWSGER----ATLTFSHLNKEDEGLYTI 346



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 81/384 (21%), Positives = 149/384 (38%), Gaps = 30/384 (7%)

Query: 457  YVQKHLTEEKGWVPAQYLMD---ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFV 513
            +++K   E++G    Q L D    N+ T  L   + +K+ K   F++     +   P FV
Sbjct: 1070 FMEKLQDEDEGTYTFQ-LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQ-EWIRKQGPHFV 1127

Query: 514  EKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572
            E L  + T +   V  +C+V    +   I W++    I   +        D + TL+I E
Sbjct: 1128 EYLSWEVTGE-CNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDGICTLLITE 1183

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEA---PLSDHGSEMTVXXXXXXXXXXXXADIL 629
               +DAG +  + K+  G   S  +L+ EA    + +   ++ +               L
Sbjct: 1184 FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQL 1243

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
                  + +  K  +   GS I    R+      +  WL   E   P  N       D  
Sbjct: 1244 YSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE---PTPN-------DKG 1293

Query: 690  MYCSVLKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VR 747
             Y  V+++ + K   + T  +      E  A    + +    EK   +V+  L  ++ ++
Sbjct: 1294 KY--VMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQ 1351

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYT 804
            +G+++ L+  V G+P P ++W KN K +        K +    +   +      D G Y 
Sbjct: 1352 EGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYG 1411

Query: 805  LKAENSEGIAETSAVITVEEPTEE 828
            L  +N  G   +   ++V  P EE
Sbjct: 1412 LVVKNKYGSETSDFTVSVFIPEEE 1435



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 55/207 (26%), Positives = 85/207 (41%), Gaps = 39/207 (18%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTK----SDGDTH 787
           P  +I+P +S  V + E+V L   + G P P +TW KN  P+   A P K    S    H
Sbjct: 141 PEFIIKP-RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 199

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-----------------PTEENA 830
           ++ I      +D   Y   A N +G     A + V+                  P     
Sbjct: 200 TLEI-NACDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGV 258

Query: 831 EPPLFINRFQ-------EITVKEKG-TIKLVARVTRNPV-----PSITWYRNNEIISPSE 877
            P  + +RF+       +++   +G T+ L  RV   P      P I WYRN   +SPS+
Sbjct: 259 TPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSK 318

Query: 878 TITQNFDGENIELVITNVDSEIDSGDY 904
            +   + GE   L  ++++ E D G Y
Sbjct: 319 WVQTLWSGERATLTFSHLNKE-DEGLY 344



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 5/117 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P PP   ++ E   S + + W  P   G+  I+Y+ VE  E  T  W  V     +   +
Sbjct: 501  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEKCEAGTENWQRVNTELPVKSPR 559

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITT 1493
             ++ +L    SY FR    N   + + SE TE   V  +  I ++P    P +N  T
Sbjct: 560  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 616



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 54/213 (25%), Positives = 98/213 (46%), Gaps = 20/213 (9%)

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDG 1053
            V K + K+ E      +++  P F+  L  +EV  +   +L+ ++ +  +   +VW +D 
Sbjct: 1103 VFKKLQKEAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYKDE 1161

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTVV-----ELP 1106
              I   + K+DF K G I  L I   S  D G Y  IL+D+     + + +V     EL 
Sbjct: 1162 REISVDE-KHDF-KDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELM 1218

Query: 1107 PEII-------TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
             E+        T L+ Q   +G +    +     D  V W  +GS I++S+ ++  + G+
Sbjct: 1219 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1278

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            +  L+I +   +D G+Y  E+ + K     TV+
Sbjct: 1279 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1311



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 9/141 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKN--ITKTQ 1437
            P PP      E+   S+ + W  P ++G + +  Y V+ +E     +W  +    I    
Sbjct: 806  PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGLNEAAIKNVY 865

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
              ++ LK   SY FR  A+N+  +   S+      V+ ET+   P  ++ + N+  +   
Sbjct: 866  LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAG--PVVAETR---PGRKEVVVNVDDDGVI 920

Query: 1498 DIELTCIFGGVPQPKVTWYRD 1518
             +   C     P+ + +W +D
Sbjct: 921  SLNFEC-DKMTPKSEFSWSKD 940



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 19/82 (23%), Positives = 36/82 (43%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +T++E   + L   V  +P P ++W +N + ++ ++     F+         N  S  DS
Sbjct: 1348 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADS 1407

Query: 902  GDYKCVASNSAGKSSHGARVTI 923
            G Y  V  N  G  +    V++
Sbjct: 1408 GKYGLVVKNKYGSETSDFTVSV 1429



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 10/124 (8%)

Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R  N+ G  +      VT+    LD P  PGK        +S+ + W+E ++     
Sbjct: 573  FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDA--KE 630

Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            ++ Y +E     + +W    N  +   + +   L T  SY FR  AVN   +S+ S+ +E
Sbjct: 631  LVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 690

Query: 1470 YYKV 1473
              +V
Sbjct: 691  AIEV 694



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETITQNFDGENI 888
           P FI + +  TV EK  +KL   +   P P +TWY+N    N   +P + I ++  G + 
Sbjct: 141 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH- 199

Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            L I   D E D+  Y+  A N  G+ S  A V +   K  F
Sbjct: 200 TLEINACDFE-DTAQYRASAMNVKGELSAYASVVVKRYKGEF 240



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  + G PPPEV W KN   L      N+  +  +T+   I  +  + S KY +   N 
Sbjct: 1358 LTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1417

Query: 1651 AGTSSVEVTLKVY 1663
             G+ + + T+ V+
Sbjct: 1418 YGSETSDFTVSVF 1430



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 20/89 (22%), Positives = 38/89 (42%), Gaps = 2/89 (2%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G  +   C V G P P+++W +    +  +    + ++    A   I  V   D+G + 
Sbjct: 1352 EGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYG 1411

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEM 611
             V KN  G  S T++  V   + +  + M
Sbjct: 1412 LVVKNKYG--SETSDFTVSVFIPEEEARM 1438



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 64/280 (22%), Positives = 115/280 (41%), Gaps = 40/280 (14%)

Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184
            FE +     +   W KD    + S  +++   G K K+   D  +DD G YSC+V ++  
Sbjct: 924  FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 983

Query: 1185 CTAILTVEEPSINFTLRLP---EFILVPANTDAYLTVEIPDETLDVTW------------ 1229
              +   ++E  +   L L    +F  VP  ++  L VEI ++     W            
Sbjct: 984  IASSYLIDEEELKRLLALSHEHKFPTVPVKSE--LAVEILEKGQVRFWMQAEKLSGNAKV 1041

Query: 1230 ---YKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK----STTKLKV 1281
               + +K + E  + K  +  +     + + K  ++D+  YT  L D K    ST  L  
Sbjct: 1042 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1101

Query: 1282 EVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH------- 1333
            +V +   K  +++R E+  K+G      + ++   + N         IKK  H       
Sbjct: 1102 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1161

Query: 1334 TKPSIDSKS------ASLTIKKVENTDAGIYKLRLENNCG 1367
             + S+D K        +L I +    DAGIY++ L+++ G
Sbjct: 1162 REISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRG 1201



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 9/90 (10%)

Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
           R+GE++ L  +VV  P     +P I W +N  P+   K + T   G+  ++T     K +
Sbjct: 281 REGETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNK-E 339

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEE 828
           DEG+YT++    E   + SA + V +   E
Sbjct: 340 DEGLYTIRVRMGEYYEQYSAYVFVRDADAE 369



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGI 1357
            I+ G  + L  +    P P   W+ N K + +  H     ++ ++A  TI  V   D+G 
Sbjct: 1350 IQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGK 1409

Query: 1358 YKLRLENNCGHADVEMNVTI 1377
            Y L ++N  G    +  V++
Sbjct: 1410 YGLVVKNKYGSETSDFTVSV 1429



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P    + EG  + L C +   P P+++WL   + +   ++ ++  E+    Y     I  
Sbjct: 1345 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAY---FTING 1401

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLK 742
            V     G Y +V  N+ G  +    + +   E+E     +E LK
Sbjct: 1402 VSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1445


>UniRef50_Q14896 Cluster: Myosin-binding protein C, cardiac-type;
            n=41; Euteleostomi|Rep: Myosin-binding protein C,
            cardiac-type - Homo sapiens (Human)
          Length = 1273

 Score =  139 bits (336), Expect = 9e-31
 Identities = 114/462 (24%), Positives = 200/462 (43%), Gaps = 28/462 (6%)

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
            +DEW+ + K++ + +       +K  S+ T++  E  D G+Y + ++N  G   V + V 
Sbjct: 707  SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 766

Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--IT 1434
            ++D P  P  P I  +   S  + W+ P   G   I+ Y++E ++  +  W+ +    I 
Sbjct: 767  VIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 826

Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI----KETKIQSPTVEKPLKN 1490
            +     + +     Y  R YAVN + +S  S  ++ +  I    + T +    V     +
Sbjct: 827  ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVS 886

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG-KKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
            +   P E +      GG+    V +  +G  +   A                      ++
Sbjct: 887  LKWRPPERVGA----GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 942

Query: 1550 CIAFNDHGE---VETSCVVGIQ---QKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPP 1601
              A N  G    V T+  V +Q   Q+P + +    ++Q  + KVG+   +    +G P 
Sbjct: 943  VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH-LRQTIQKKVGEPVNLLIPFQGKPR 1001

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P+V W K G  L  + E +I      +++ I+  +R HS  Y +            + L+
Sbjct: 1002 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1060

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            V DKPS P+  + + +    +V +EWKPP D G  EL  Y ++K +     W  V +  R
Sbjct: 1061 VVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1119

Query: 1722 DVETYC-IQKLNENCEYMFRVIAQNPVGFSE--ALESEPIVI 1760
               T+C + +L     Y FRV +QN VGFS+  A   EP+ I
Sbjct: 1120 --RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFI 1159



 Score =  112 bits (269), Expect = 1e-22
 Identities = 109/468 (23%), Positives = 195/468 (41%), Gaps = 38/468 (8%)

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            E +    + T +  S+  ++  ++     YT+   N  G   V +T+KV D P  P  P 
Sbjct: 719  ETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK 778

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLN 1732
            I   +  +S T++W+PP  DGG  +  Y +E+ +  + RW+++  D+ +++ ++  +++ 
Sbjct: 779  ISN-VGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQEL-SHEARRMI 836

Query: 1733 ENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
            E   Y  RV A N +G S  +  S+P +    +  PS          + + +V + W P 
Sbjct: 837  EGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS-EPTHLAVEDVSDTTVSLKWRPP 892

Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTS 1848
            E+ G   +  Y VE   EG  +W            I  + L       FR+ A N  G  
Sbjct: 893  ERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPG 952

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KT 1906
             P T+ + +T+ + L  P       + ++  + V           G P+ N +I F  K 
Sbjct: 953  APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV-----------GEPV-NLLIPFQGKP 1000

Query: 1907 VKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA----ENTVGVSLPTESQSVRLEK 1961
                +WTK    + G   E  I N    D I+F  +A      T  V++  E+   +   
Sbjct: 1001 RPQVTWTKEGQPLAG--EEVSIRN-SPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1057

Query: 1962 HATVPSPPTAPLEIRMV---GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018
               V   P+ P ++R+    G N+ +  W  P+  G   L GY +   D     W  V +
Sbjct: 1058 VLQVVDKPSPPQDLRVTDAWGLNVAL-EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1116

Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
                     + +L   + Y  R++++N +G S+   + +    IP  G
Sbjct: 1117 -HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPG 1163



 Score =  111 bits (267), Expect = 2e-22
 Identities = 80/257 (31%), Positives = 129/257 (50%), Gaps = 11/257 (4%)

Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            F +KL+  ++V +     L VE+    A+V W ++G+ I+    +Y FE  G  R L I 
Sbjct: 365  FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQ-MSGRYIFESIGAKRTLTIS 423

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR-LQNQKVNKGNKATFEIELTKGDAL 1136
              S+ D+  Y C++  E C+ E+ V E PP +ITR L++Q V  G +  FE E+++  A 
Sbjct: 424  QCSLADDAAYQCVVGGEKCSTELFVKE-PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ 482

Query: 1137 VRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
            V+W KDG E+      +     DG++  L I +  L+DAG Y+      +  A L V+E 
Sbjct: 483  VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEK 542

Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTE-KFTLISDVKKRT 1252
             +     + + ++V A   A    E+ DE +   W K  K ++ D+  K + I  V K  
Sbjct: 543  KLEVYQSIAD-LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK-- 599

Query: 1253 LIIRKCTEDDQCEYTCV 1269
            L I   T  D+ +Y+ V
Sbjct: 600  LTIDDVTPADEADYSFV 616



 Score =  101 bits (241), Expect = 3e-19
 Identities = 80/284 (28%), Positives = 124/284 (43%), Gaps = 7/284 (2%)

Query: 924  DVEKVT-FVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE-GR 980
            D +K T F K L+ +Y+  +G  + L  + + H    KW  N +EI  M  R I +  G 
Sbjct: 358  DEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQ-MSGRYIFESIGA 416

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                        D    +C+V  ++ ST L VKE      R L+D  V        E E+
Sbjct: 417  KRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV 476

Query: 1041 NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            + E A V W +DG E+ + +  KY F+K G    L I    + D G Y+         AE
Sbjct: 477  SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE 536

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            + V E   E+   + +  V   ++A F+ E++  +    W K+G E+   + I+++  G+
Sbjct: 537  LIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGR 596

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKC--TAILTVEEPSINFTLR 1201
              KL I D    D  +YS       C  +A L   E  I+F  R
Sbjct: 597  VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPR 640



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 54/168 (32%), Positives = 77/168 (45%), Gaps = 3/168 (1%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            +V+KG+K    +EL   DA V+W K+G EIQ S        G K+ L I  C L D   Y
Sbjct: 374  QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGRYIFESIGAKRTLTISQCSLADDAAY 433

Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK--KS 1234
             C VG  KC+  L V+EP +  T  L E  LV          E+ +E   V W K   + 
Sbjct: 434  QCVVGGEKCSTELFVKEPPVLITRPL-EDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 492

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
              E+T K+    D ++  LII +   +D   Y       ++  +L V+
Sbjct: 493  TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQ 540



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 19/239 (7%)

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            K G  V LL+ +Q  P+P   W    + +   +            L I+      +G Y+
Sbjct: 985  KVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQ 1043

Query: 1360 L--RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            +  R+EN    A + + V  +DKPSPP    + +    ++ + W  P++ GN+ +  Y V
Sbjct: 1044 VTVRIENMEDKATLVLQV--VDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1101

Query: 1418 EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +  +  T EW +V ++  +T   +  L   + Y FR ++ N V  SD + TT+    I  
Sbjct: 1102 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1161

Query: 1477 TKI-------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
              I             ++P+  +PL N +        L C   G P+PK++W+++G  L
Sbjct: 1162 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL 1220



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 49/155 (31%), Positives = 73/155 (47%), Gaps = 8/155 (5%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            +E  +++DE ++ ++ +N VG     E Q     K   VP  P AP +I  VG +     
Sbjct: 737  VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQ 790

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P +DGG P+LGY +  +      WM +    +  L    R + E   Y +R+YA N 
Sbjct: 791  WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNA 850

Query: 2047 IGLSEPLESDEPFKVI--PGEGSHADEEPGEQTEV 2079
            IG+S P  + +PF  I  P E +H   E    T V
Sbjct: 851  IGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTV 885



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 1/97 (1%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            S AP F + L  +    G T    C V G P+P+I+WF+    +     F+M +    V 
Sbjct: 1177 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVL 1235

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            TL IR+  P D G + C A N  G A     L V  P
Sbjct: 1236 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1272



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            E+ S  F  +L     V       LTVE+ D   +V W K    I+ + ++   S   KR
Sbjct: 359  EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGRYIFESIGAKR 418

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
            TL I +C+  D   Y CV+   K +T+L    V+ PP ++
Sbjct: 419  TLTISQCSLADDAAYQCVVGGEKCSTEL---FVKEPPVLI 455



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 26/77 (33%), Positives = 37/77 (48%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            +V  G+ A FE E  +    VRW + GS+I  SN   L  +G +  L + +    D G Y
Sbjct: 20   EVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79

Query: 1177 SCEVGNSKCTAILTVEE 1193
            +   G+SK    L V E
Sbjct: 80   AVIAGSSKVKFDLKVIE 96



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
            K+ +  F +K +  EV     A+ E E       V W+R G  I    NKY     G   
Sbjct: 6    KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISAS-NKYGLATEGTRH 64

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
             L +R     D+G Y+ I        ++ V+E
Sbjct: 65   TLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 18/72 (25%), Positives = 34/72 (47%)

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            ++   + G P P++ W+KNG  L  D  + + +K+    + I++        Y   A+N 
Sbjct: 1198 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNL 1257

Query: 1651 AGTSSVEVTLKV 1662
             G +  E  L+V
Sbjct: 1258 QGEARCECRLEV 1269



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789
            E P   +PL +  V  G + +L   V G+P+P I+W KN   +         S     ++
Sbjct: 1178 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1237

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
             I KP    D G+Y  +A N +G A     + V  P
Sbjct: 1238 EIRKPCPF-DGGIYVCRATNLQGEARCECRLEVRVP 1272



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 22/177 (12%)

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV----AVNREGEASLP 722
           WL  G+E+VPD  I V+    +H     L I +V    E  Y+ V    A N   +    
Sbjct: 576 WLKNGKELVPDSRIKVSHIGRVHK----LTIDDVTPADEADYSFVPEGFACNLSAKLHFM 631

Query: 723 IVLKIKTGEKEPPQVIEPL-----KSMIVRQGESVILSAQVVGNPRPTITWCK-----NN 772
            V       +EPP++          +++V  G  + L   + G+P PT+ W K     N 
Sbjct: 632 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 691

Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            P +  P   +    S   +  KK+  E    ++ E +    +  ++ TVE   +E+
Sbjct: 692 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETT----KDRSIFTVEGAEKED 744



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVY--TL 805
            GE V L     G PRP +TW K  +P+        +  T +I  ++  +    G Y  T+
Sbjct: 987  GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1046

Query: 806  KAENSEGIAETSAVITVEEPT 826
            + EN E  A T  +  V++P+
Sbjct: 1047 RIENMEDKA-TLVLQVVDKPS 1066


>UniRef50_UPI000065FB77 Cluster: Myomesin-1 (190 kDa titin-associated
            protein) (190 kDa connectin- associated protein).; n=1;
            Takifugu rubripes|Rep: Myomesin-1 (190 kDa
            titin-associated protein) (190 kDa connectin- associated
            protein). - Takifugu rubripes
          Length = 1393

 Score =  138 bits (335), Expect = 1e-30
 Identities = 108/447 (24%), Positives = 190/447 (42%), Gaps = 19/447 (4%)

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EISRESVTIEWKPPLD 1692
            L       + +  ++   T  + VT +   +   P  P+ ++  E ++  V + WKPP  
Sbjct: 376  LTSKEKETFQVYGTSAPWTGQIIVTEEEPAEGIVPGRPLELQVTEATKNYVVLSWKPPAG 435

Query: 1693 DGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             G LE   Y +EK     + W +V  ++      + +  L E   Y FRV   N  G  E
Sbjct: 436  KG-LEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYSFRVRCCNSAGVGE 494

Query: 1752 ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
              + +E   +   LD+PS           D  SV ++W  S       ++ Y +E    G
Sbjct: 495  PSDPTEATTVGDKLDIPSAPGRVVPTRNTDT-SVVVSWEASRD--ARELVGYYIEGSIVG 551

Query: 1811 KK-WKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
             + W+          R     L+    Y FR+ A N  G S      + + +   +  P+
Sbjct: 552  SQVWEPCNNKPVNGTRFICHGLTTGEKYVFRVRALNAAGLSQFSPESEPVEVKAAIASPT 611

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSVH 1923
             P    V ES   S+ L W +P S GG+ +T Y ++++ V     GK W +      S  
Sbjct: 612  PPYGITVLESVRDSMVLAWKQPTSIGGADVTGYFVDYREVVDGLPGK-WHEANVRAISER 670

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNI 1982
             + + ++KE  +  F++ A N  GV +P+      L +  T+  P P   L+IR V S+ 
Sbjct: 671  AYRVTDLKENRKYQFQVRAANIAGVGVPSLPSETFLCEEWTIAVPGPPHDLQIREVRSDS 730

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            ++  W  P + G  P+ G+ + ++  D  +  W  V       +   I++L E  T++ R
Sbjct: 731  LVLLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKMFLKIKNLKEAETFVFR 790

Query: 2041 IYARNEIGLSEPLESDEPFKVIPGEGS 2067
            + A+N+ G+ +  E+ EP   +   G+
Sbjct: 791  VRAQNKAGVGKSSEATEPVSAVTKPGT 817



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 57/204 (27%), Positives = 96/204 (47%), Gaps = 17/204 (8%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL--PTK----SDGDTH 787
           P  VI+P +S  V + + V L   V G P P + W KNN  +  L  P K    S  + H
Sbjct: 20  PEFVIKP-RSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKIDSSYNIH 78

Query: 788 SITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEP--PLFINRFQEITV 844
           S+ I K    +D   Y + A NS+G ++  ++V+    P  E         +++F     
Sbjct: 79  SLEINKCD-FEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDKFGVSFG 137

Query: 845 KEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
           +E  T+ L   V   PV     P I WYR++ ++SPS+    ++ G+   L +++++ E 
Sbjct: 138 REGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDRATLTLSHLNKE- 196

Query: 900 DSGDYKCVASNSAGKSSHGARVTI 923
           D G Y    +  +G  ++ A V +
Sbjct: 197 DEGLYTLRVTTKSGYETYSAYVFV 220



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 18/210 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI-SVAIESDMHMYC 692
           P F  KP++  V E   + L C +   P+P + W      I P  N     I+S  +++ 
Sbjct: 20  PEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKIDSSYNIHS 79

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE------PPQVIEPLKSMIV 746
             L+I          Y V A+N +GE S    + +K G            +++       
Sbjct: 80  --LEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDKFGVSFG 137

Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVK 798
           R+GE++ L   VV  P     +P I W +++    P K       GD  ++T+    K +
Sbjct: 138 REGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDRATLTLSHLNK-E 196

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEE 828
           DEG+YTL+     G    SA + V +   E
Sbjct: 197 DEGLYTLRVTTKSGYETYSAYVFVRDADAE 226



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 67/299 (22%), Positives = 124/299 (41%), Gaps = 35/299 (11%)

Query: 651  ILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            ++L+C++  I  E    W   G+EI  DE++S   E  +      L+I  + K   G Y 
Sbjct: 1099 VVLKCKVGNIKKETSALWYKDGQEIKADEHLSFT-EGVLK-----LEIAQISKKDAGVYE 1152

Query: 710  VVAVNREGEASLPIVLKIKTGEKEPPQVIE-------PLKSMIVRQGESVILSAQVVGNP 762
            VV  +  G+ +  + LK +  +    +V         PLK     QG  +        N 
Sbjct: 1153 VVLKDDRGKDTSTLNLKDQGFKDLMNEVFSFIANSSTPLKITSTDQGIRLYTFVSYY-ND 1211

Query: 763  RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
               +TW   N  +     + +   G+   + I +P + KD G Y ++  + +G    +  
Sbjct: 1212 LLQVTWQYKNSAIAFSDRIKSGVVGEQIFLQITEPTE-KDMGEYAIEFYDGKGGVRRTVE 1270

Query: 820  IT---VEEPTEENAEPPLFINRF-----------QEITVKEKGTIKLVARVTRNPVPSIT 865
            +T    E+   E     +++  F             +T++E   + L   ++ +PVP +T
Sbjct: 1271 LTGQAFEDAYAEFQRLKIYLCFFTGRARVAGGLPDVVTIQEGKALSLTCNISGDPVPEVT 1330

Query: 866  WYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W +N++ I+    I   F+ G+     +T V++  DSG Y  +  N  G  S    V++
Sbjct: 1331 WLKNDKEITTDGHIILKFESGKFANFFVTGVNTS-DSGKYSILVKNKYGTESGDFTVSV 1388



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 3/114 (2%)

Query: 498 FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
           F++  ++    +P FV K R     +   V+  C V G+P P++ W++    I P  +  
Sbjct: 8   FKRMNTDSLMHSPEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPG 67

Query: 558 MYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHG 608
            Y  D   N+ +L I +   ED   +   A N+ G  S+   ++V+  P+S++G
Sbjct: 68  KYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYG 121



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 28/219 (12%)

Query: 1227 VTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            V WYK    I+   +  K+ + S     +L I KC  +D  +Y    +++K        V
Sbjct: 51   VVWYKNNVTIDPLANPGKYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASV 110

Query: 1284 V-----------EFPPKIVD-----YEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            V            F   IVD     + RE   +  G  V +    Q + QP  +W  +  
Sbjct: 111  VVKNGPVSEYGITFQTHIVDKFGVSFGREGETMSLGCTVVIYPVLQGY-QPGIQWYRDDV 169

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---- 1382
            ++   K          A+LT+  +   D G+Y LR+    G+      V + D  +    
Sbjct: 170  LLSPSKWQHMHWSGDRATLTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFVRDADAEVEG 229

Query: 1383 PPGKP---NILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             PG P     L+ +   I + W +P   G ++I+ Y V+
Sbjct: 230  APGSPLDVRCLDANKDYIIVTWKQPAVDGGNSILGYFVD 268



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 4/93 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN--ITKT 1436
            P PP    I E+ S S+ + W  P   G   I  + V+ +E D  E  W  V N    K 
Sbjct: 715  PGPPHDLQIREVRSDSLVLLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKM 774

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
               I+NLK   ++ FR  A N+  +  +SE TE
Sbjct: 775  FLKIKNLKEAETFVFRVRAQNKAGVGKSSEATE 807



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 67/282 (23%), Positives = 110/282 (39%), Gaps = 38/282 (13%)

Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--GNSKCTAIL 1189
            K +    W+KDG EI+   H+  T +G   KL+I      DAG Y   +     K T+ L
Sbjct: 1109 KKETSALWYKDGQEIKADEHLSFT-EG-VLKLEIAQISKKDAGVYEVVLKDDRGKDTSTL 1166

Query: 1190 TVEEPSINFTL-RLPEFI------LVPANTD----AYLTVEIPDETLDVTWYKKKSVIED 1238
             +++      +  +  FI      L   +TD     Y  V   ++ L VTW  K S I  
Sbjct: 1167 NLKDQGFKDLMNEVFSFIANSSTPLKITSTDQGIRLYTFVSYYNDLLQVTWQYKNSAIAF 1226

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYER- 1295
            +++       ++  L I + TE D  EY     D K   +  VE+    F     +++R 
Sbjct: 1227 SDRIKSGVVGEQIFLQITEPTEKDMGEYAIEFYDGKGGVRRTVELTGQAFEDAYAEFQRL 1286

Query: 1296 -------------------EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
                                  I+ G  ++L  +    P P   W+ N K I    H   
Sbjct: 1287 KIYLCFFTGRARVAGGLPDVVTIQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIIL 1346

Query: 1337 SIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              +S K A+  +  V  +D+G Y + ++N  G    +  V++
Sbjct: 1347 KFESGKFANFFVTGVNTSDSGKYSILVKNKYGTESGDFTVSV 1388



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 54/269 (20%), Positives = 107/269 (39%), Gaps = 31/269 (11%)

Query: 1466 ETTEYYKVIK-ETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            E  E++K +  ++ + SP  V KP  +   E  + + L C   G P P+V WY++   + 
Sbjct: 3    EHEEHFKRMNTDSLMHSPEFVIKPRSHTVWE-KQCVRLHCTVSGWPDPRVVWYKNNVTID 61

Query: 1524 TAK--ATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV---- 1572
                   Y+     N                Y+  A N  GE+     V ++  PV    
Sbjct: 62   PLANPGKYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYG 121

Query: 1573 ITISNEDIK----------QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
            IT     +           +   +G   ++  V++G  P  + WY++   L   K  ++ 
Sbjct: 122  ITFQTHIVDKFGVSFGREGETMSLGCTVVIYPVLQGYQPG-IQWYRDDVLLSPSKWQHMH 180

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG----PVIMR-- 1676
                 + + +  L +     YT+  +  +G  +    + V D  ++ EG    P+ +R  
Sbjct: 181  WSGDRATLTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFVRDADAEVEGAPGSPLDVRCL 240

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            + +++ + + WK P  DGG  +  Y +++
Sbjct: 241  DANKDYIIVTWKQPAVDGGNSILGYFVDR 269



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGP---VIMREISRESVT 1684
            R+ +LK +   ++ + A+N AG    S    T    +      GP   + +RE+  +S+ 
Sbjct: 673  RVTDLKENRKYQFQVRAANIAGVGVPSLPSETFLCEEWTIAVPGPPHDLQIREVRSDSLV 732

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            + WKPP+  G   +  + ++  E D     W  V +   +     I+ L E   ++FRV 
Sbjct: 733  LLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKMFLKIKNLKEAETFVFRVR 792

Query: 1743 AQNPVGFSEALE-SEPI 1758
            AQN  G  ++ E +EP+
Sbjct: 793  AQNKAGVGKSSEATEPV 809



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 12/136 (8%)

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFD 884
           T+     P F+ + +  TV EK  ++L   V+  P P + WY+NN  I P +       D
Sbjct: 13  TDSLMHSPEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKID 72

Query: 885 GE-NI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEK--VTFVKHLQKS 937
              NI  L I   D E D+  Y+  A NS G+ S  A V +    V +  +TF  H+   
Sbjct: 73  SSYNIHSLEINKCDFE-DTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDK 131

Query: 938 YET---EEGKTVILEC 950
           +      EG+T+ L C
Sbjct: 132 FGVSFGREGETMSLGC 147



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 6/106 (5%)

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID---TTEW 1427
            VE+   I   P+PP    +LE    S+ + W +P + G + +  Y V+Y+E+      +W
Sbjct: 601  VEVKAAIAS-PTPPYGITVLESVRDSMVLAWKQPTSIGGADVTGYFVDYREVVDGLPGKW 659

Query: 1428 --ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
               +V+ I++    + +LK N  Y+F+  A N   +   S  +E +
Sbjct: 660  HEANVRAISERAYRVTDLKENRKYQFQVRAANIAGVGVPSLPSETF 705



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 513 VEKLRPKHTPDGSTVQFECQVEGYP-----RPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
           V+K       +G T+   C V  YP     +P I W+R   ++ PS+   M++  D  AT
Sbjct: 129 VDKFGVSFGREGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDR-AT 187

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           L +  +  ED G +T      +G+ + +  + V
Sbjct: 188 LTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFV 220



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 38/161 (23%), Positives = 68/161 (42%), Gaps = 30/161 (18%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVM 1984
            + ++ ++DE ++ +      G    +    VR +  A V   P +PL++R + +N   ++
Sbjct: 190  LSHLNKEDEGLYTLRVTTKSGYETYSAYVFVR-DADAEVEGAPGSPLDVRCLDANKDYII 248

Query: 1985 TSWGTPEWDGGAPLLGYNI--------AIR---DVTKT----------------MWMEVG 2017
             +W  P  DGG  +LGY +         +R   D TK+                 W++  
Sbjct: 249  VTWKQPAVDGGNSILGYFVDRSVGPAKTLRLEDDGTKSEAELFSSTCRCEVGTNHWIQCN 308

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
               V   +F +  L E  +Y+ R+ A N  G+S P    EP
Sbjct: 309  DTPVKFARFPVTGLVEGRSYLFRVRAVNNSGMSHPSRVSEP 349



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P    + EG  + L C +   P P++ WL   +EI  D +I +  ES      +   +T 
Sbjct: 1304 PDVVTIQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKF---ANFFVTG 1360

Query: 700  VKKFQEGTYTVVAVNREGEAS 720
            V     G Y+++  N+ G  S
Sbjct: 1361 VNTSDSGKYSILVKNKYGTES 1381



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  I G P PEV W KN  ++  D    +  +  K +   +  +  S S KY+I   N 
Sbjct: 1317 LTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGKYSILVKNK 1376

Query: 1651 AGTSSVEVTLKVY 1663
             GT S + T+ V+
Sbjct: 1377 YGTESGDFTVSVF 1389



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 18/81 (22%), Positives = 33/81 (40%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G  +   C + G P P++TW +    I       + ++    A   +  V   D+G ++
Sbjct: 1311 EGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGKYS 1370

Query: 583  CVAKNAAGFASSTTELIVEAP 603
             + KN  G  S    + V  P
Sbjct: 1371 ILVKNKYGTESGDFTVSVFIP 1391



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 8/117 (6%)

Query: 1384 PGKPNILEIDSSSIN---ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            PG+P  L++  ++ N   + W  P   G   ++YY VE     T  W  V     +   +
Sbjct: 410  PGRPLELQVTEATKNYVVLSWKPPAGKGLEGVMYY-VEKCVSGTDSWQRVNTEIPVKSPR 468

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITT 1493
             ++ +L    SY FR    N   + + S+ TE   V  +  I S P    P +N  T
Sbjct: 469  FALFDLAEGKSYSFRVRCCNSAGVGEPSDPTEATTVGDKLDIPSAPGRVVPTRNTDT 525



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 19/85 (22%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802
            +++G+++ L+  + G+P P +TW KN+K +     +  K +    +   +      D G 
Sbjct: 1309 IQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGK 1368

Query: 803  YTLKAENSEGIAETSAVITVEEPTE 827
            Y++  +N  G       ++V  P E
Sbjct: 1369 YSILVKNKYGTESGDFTVSVFIPDE 1393



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 6/108 (5%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435
            LD PS PG+        +S+ + W+   +     ++ Y +E   + +  W    N  +  
Sbjct: 508  LDIPSAPGRVVPTRNTDTSVVVSWEASRDARE--LVGYYIEGSIVGSQVWEPCNNKPVNG 565

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
            T+     L T   Y FR  A+N   +S  S  +E  +V  +  I SPT
Sbjct: 566  TRFICHGLTTGEKYVFRVRALNAAGLSQFSPESEPVEV--KAAIASPT 611


>UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscle;
           n=34; Euteleostomi|Rep: Myosin light chain kinase,
           smooth muscle - Mus musculus (Mouse)
          Length = 1941

 Score =  138 bits (333), Expect = 2e-30
 Identities = 109/433 (25%), Positives = 186/433 (42%), Gaps = 54/433 (12%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+ +S  P F  + + +   +G TV+F C+V G P+P + WF +   ++  +     Y+D
Sbjct: 395 SQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYED 454

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
                L +      D+  ++C A N+ G  S +  L+V+ P                   
Sbjct: 455 GVSHHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPN------------------ 496

Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                 L    P+FS   K   V EG D +L C +   P P + WL  G+ I    +I  
Sbjct: 497 ------LAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICE 550

Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----GEKE----- 733
           A  +++H       I +      GTYT +A N  G+ S    + ++     GE+E     
Sbjct: 551 AGVAELH-------IQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSP 603

Query: 734 ------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDG 784
                  P  ++ L  + V  G  V ++ QV GNP P + W  +   ++       +  G
Sbjct: 604 ARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKG 663

Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
             HS+ I +    +D G YT +A NS G   T AV+TV+EP   +   P FI++ + +T 
Sbjct: 664 GWHSLCIQEVFP-EDTGTYTCEAWNSAGEVRTRAVLTVQEP--HDGTQPWFISKPRSVTA 720

Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGD 903
               ++ +   +  +P P++ W R+   +S      +    E++  LV+ NV     +G 
Sbjct: 721 TLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNV-QPWHAGQ 779

Query: 904 YKCVASNSAGKSS 916
           Y+ +  N  G+ S
Sbjct: 780 YEILLKNRVGECS 792



 Score =  119 bits (287), Expect = 8e-25
 Identities = 91/365 (24%), Positives = 155/365 (42%), Gaps = 27/365 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F  +P++Q V EG  +   C +  IP+PD+ W  +G  +   E I+   E  +  +  
Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE--KEPPQVIEPLKSMIVRQGES 751
           +L+    +      Y+  A N  G+ S    L +      +  P     LK  +V +G+ 
Sbjct: 462 LLR---ARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQD 518

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            +L   V G P P +TW  N +P++   +  +     + I +    +D G YT  AEN+ 
Sbjct: 519 FVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHI-QDALPEDRGTYTCLAENAM 577

Query: 812 GIAETSAVITVEE------------PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
           G    SA +TV+E            P       P+F+    ++ V +   + +  +V+ N
Sbjct: 578 GQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGN 637

Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
           P P + W  +   I  SE       G    L I  V  E D+G Y C A NSAG+    A
Sbjct: 638 PPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPE-DTGTYTCEAWNSAGEVRTRA 696

Query: 920 RVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDH 972
            +T+    D  +  F+    +S     G++V++ C  +     +  W  + + +S    H
Sbjct: 697 VLTVQEPHDGTQPWFISK-PRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGH 755

Query: 973 REIIQ 977
            E++Q
Sbjct: 756 FELLQ 760



 Score =  104 bits (250), Expect = 2e-20
 Identities = 72/241 (29%), Positives = 103/241 (42%), Gaps = 9/241 (3%)

Query: 487 KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           K +  +D   V   P +E    AP F+   R     +G+T +FE +V GYP PQ+TW R+
Sbjct: 14  KTSHSVDPSKVSSMPLTE----APAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRK 69

Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
              I     F +        +LVI  V  ED G +TC A N +G    T EL VE   S 
Sbjct: 70  GQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVELTVEGN-SM 128

Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
              +  V              I    PP F+ K     V EG      C++   P P + 
Sbjct: 129 KKRDQPVLSKASGFPGETRPSIWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVT 188

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
           WL     + P   +S++ ++ M     +L+I  V +   G YT + VN  G+AS+   L 
Sbjct: 189 WLKGNVPLQPSARVSMSEKNGM----QILEIRGVTRDDLGVYTCMVVNGSGKASMSAELS 244

Query: 727 I 727
           I
Sbjct: 245 I 245



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 70/239 (29%), Positives = 109/239 (45%), Gaps = 30/239 (12%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           +  + +APIF++ L      DGS V    QV G P P++ W      I+ S+DF  +   
Sbjct: 604 ARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFH-FEQK 662

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
               +L I+EVFPED GT+TC A N+AG   +   L V+ P   H               
Sbjct: 663 GGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEP---H--------------- 704

Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                  +G  P F  KP++     G  +L+ C +   P P + WL  G  +  D     
Sbjct: 705 -------DGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFE 757

Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEP 740
            ++++  ++  VLK  NV+ +  G Y ++  NR GE S  + L +  +  + PP+  EP
Sbjct: 758 LLQNE-DVFTLVLK--NVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSRAPPRGREP 813



 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 55/200 (27%), Positives = 92/200 (46%), Gaps = 1/200 (0%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+I+ +  + +++ G  V L            +W+   K I++ +H K       + LT
Sbjct: 1259 PPQIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLT 1318

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405
            I        G Y L +EN  G    ++N+T++DKP PP G P   +I SSS+ + W    
Sbjct: 1319 ILAARQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1378

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              G S +  Y VE  + +   W  +     T  ++Q+L  +  Y+FR  AVN    S+ S
Sbjct: 1379 YDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPS 1438

Query: 1466 ETTEYYKVIKETKIQSPTVE 1485
            + +E   V ++ +     VE
Sbjct: 1439 QESELTAVGEKPEEPKDEVE 1458



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 45/126 (35%), Positives = 72/126 (57%), Gaps = 1/126 (0%)

Query: 486  KKLNEKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
            +KL  + D    F +  +EE+  + P F + +R     +GS  +F+C++EGYP P++ WF
Sbjct: 1806 EKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 1865

Query: 545  RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
            +    I+ S+ FQ+ YD+D   +L+I +V  +D   +TC A N+ G A+ T ELIVE   
Sbjct: 1866 KDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1925

Query: 605  SDHGSE 610
               G E
Sbjct: 1926 EGEGEE 1931



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 49/176 (27%), Positives = 79/176 (44%), Gaps = 3/176 (1%)

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
            QK + G+   +   + G  P    W K   +++  +   +   E  S + I   ++ H  
Sbjct: 1269 QKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLTILAARQEHCG 1328

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
             YT+   N  G+   +V L V DKP  P G     +I   S+T+ W     DGG  +  Y
Sbjct: 1329 CYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1388

Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756
             +E  + ++  W ++A       ++ +Q L  + EY FRV A N  G SE + ESE
Sbjct: 1389 NVEIWDTEDKVWKELATCRS--TSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESE 1442



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 78/411 (18%), Positives = 153/411 (37%), Gaps = 37/411 (9%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH-TKPSIDSKSASLT 1346
            P+     +   +  G  V  + +    P+P+  W +    +++ +  T+   D  S  L 
Sbjct: 402  PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            + +    D+  Y     N+ G      ++ +        +PN+ +   S  ++  D    
Sbjct: 462  LLRARTRDSRKYSCTASNSLGQVSCSWSLLV-------DRPNLAQTAPSFSSVLKDSVVI 514

Query: 1407 TGNSTIIYYVVEYQEIDTTEWI----------SVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
             G   ++   V+        W+          S+      +  IQ+        +   A 
Sbjct: 515  EGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHIQDALPEDRGTYTCLAE 574

Query: 1457 NEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIE--------LTCIF 1505
            N +     S T    +   E + +   SP   KP+  I  +   D++        +T   
Sbjct: 575  NAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634

Query: 1506 GGVPQPKVTWYRDGKKLKTAK-ATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
             G P P+V W  DG +++ ++   +E +                  Y C A+N  GEV T
Sbjct: 635  SGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 694

Query: 1562 SCVVGIQQKPVIT---ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617
              V+ +Q+    T     ++       +G   L++  I G P P V W ++G  L  D  
Sbjct: 695  RAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSG 754

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
             + +   E    + +K ++  H+ +Y I   N  G  S +V+L +++ PS+
Sbjct: 755  HFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSR 805



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 28/217 (12%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHS 788
           E P  I P +++ V++G +     +V G P P +TW +  + +    + L       T S
Sbjct: 31  EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFS 90

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--------EPTEENAE--------- 831
           + I   ++ +D+G YT +A N  G  + +  +TVE        +P    A          
Sbjct: 91  LVIHTVRE-EDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPS 149

Query: 832 -----PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                PP F  +     VKE    +   ++T  P P +TW + N  + PS  ++ +    
Sbjct: 150 IWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNG 209

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              L I  V  + D G Y C+  N +GK+S  A ++I
Sbjct: 210 MQILEIRGVTRD-DLGVYTCMVVNGSGKASMSAELSI 245



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 52/195 (26%), Positives = 90/195 (46%), Gaps = 10/195 (5%)

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
            G  +P + ++P+ +    +    I +AQ  G+ +P      N +P +  P K  G+  S 
Sbjct: 1026 GNAKPTETLKPVGNTKPAETLKPIANAQPSGSLKPVT----NAQPAE--PQKPVGNAKSA 1079

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
               KP   K+E V  +K + +    +  A    + P E     P+F  + Q++ V E   
Sbjct: 1080 ETSKPAG-KEE-VKEVKNDVNCKKGQVGATGNEKRP-ESQGSAPVFKEKLQDVHVAEGEK 1136

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            + L  +V  +P  ++TW  N + +  ++ I    +G    + I     E D G YKCVA 
Sbjct: 1137 LLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPE-DRGLYKCVAK 1195

Query: 910  NSAGKSSHGARVTID 924
            NSAG++    +VT+D
Sbjct: 1196 NSAGQAECSCQVTVD 1210



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 1/98 (1%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            E Q  AP+F EKL+  H  +G  +  +CQV   P   +TW      +K ++ F +   + 
Sbjct: 1114 ESQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTK-FIVLAQEG 1172

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +  ++ I +  PED G + CVAKN+AG A  + ++ V+
Sbjct: 1173 SRFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVD 1210



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 93/418 (22%), Positives = 159/418 (38%), Gaps = 49/418 (11%)

Query: 808  ENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            ++S G +  +  +T   P E   E   P F ++ Q   V E  T+K +  V+  P P + 
Sbjct: 375  QSSLGGSVGNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVG 434

Query: 866  WYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            W+     +   E IT+ + DG +  L +    +  DS  Y C ASNS G+ S    + +D
Sbjct: 435  WFLEGIPVRRREGITEVYEDGVSHHLCLLRARTR-DSRKYSCTASNSLGQVSCSWSLLVD 493

Query: 925  ----VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQE 978
                 +       + K     EG+  +L C    T + +  W  N + I        I E
Sbjct: 494  RPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQ---FAHSICE 550

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET------------------I 1016
                          D G   C+ ++       S  + V+E                    
Sbjct: 551  AGVAELHIQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIA 610

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++ L D +V +     + V+++     +V+W  DG  I+  ++ + FE++G    L 
Sbjct: 611  PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESED-FHFEQKGGWHSLC 669

Query: 1076 IRNTSVHDEGEYSCIL---RDESCTAEVTVVELP-----PEIITRLQNQKVNKGNKATFE 1127
            I+     D G Y+C       E  T  V  V+ P     P  I++ ++     G      
Sbjct: 670  IQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLIS 729

Query: 1128 IELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              +  GD    V W +DG  + + S H +L  +     L + +     AG+Y   + N
Sbjct: 730  CAIA-GDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKN 786



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 5/132 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P   E L+ + V +GE ++L  QV+ +P  T+TW  N K +K    +    +G   S++I
Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSI 1179

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTI 850
             K    +D G+Y   A+NS G AE S  +TV++  T EN + P   +R  + ++      
Sbjct: 1180 EKALP-EDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGT 1238

Query: 851  KLVARVTRNPVP 862
            +  A V + P P
Sbjct: 1239 ESDATVKKKPAP 1250



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 88/414 (21%), Positives = 161/414 (38%), Gaps = 45/414 (10%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071
            + T P F  + Q  EV E        E++     DV W  +G  ++ ++   +  + G  
Sbjct: 398  ESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVS 457

Query: 1072 RKLYIRNTSVHDEGEYSCI----LRDESCTAEVTV-----VELPPEIITRLQNQKVNKGN 1122
              L +      D  +YSC     L   SC+  + V      +  P   + L++  V +G 
Sbjct: 458  HHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQ 517

Query: 1123 KATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178
                   +    A  V W  +G  IQF++ I    +    +L I D   +D G Y+C   
Sbjct: 518  DFVLRCSVQGTPAPRVTWLLNGQPIQFAHSI---CEAGVAELHIQDALPEDRGTYTCLAE 574

Query: 1179 -EVGNSKCTAILTVEE-----------------PSINFTLRLPEFILVPANTDAYLTVEI 1220
              +G   C+A +TV+E                 P     L+    + V   +   +TV++
Sbjct: 575  NAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634

Query: 1221 P-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
              +   +V W    + I+++E F         +L I++   +D   YTC   ++    + 
Sbjct: 635  SGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 694

Query: 1280 K-VEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK- 1332
            + V  V+ P     P  +   R      G  V +       P P   W+ + + + K   
Sbjct: 695  RAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSG 754

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PP 1384
            H +   +    +L +K V+   AG Y++ L+N  G    ++++ + + PS  PP
Sbjct: 755  HFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSRAPP 808



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 32/224 (14%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F   P+   V EG+    E R+   PEP + W  KG+ I         ++  +    S
Sbjct: 33  PAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRF--LLDCGVRGTFS 90

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK------------------TGEKEP- 734
           ++ I  V++  +G YT  A N  G   + + L ++                   GE  P 
Sbjct: 91  LV-IHTVREEDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPS 149

Query: 735 ------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS 788
                 P+    L   +V++G+    S ++ G P P +TW K N P++     S  + + 
Sbjct: 150 IWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNG 209

Query: 789 ITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
           + IL+ + V   D GVYT    N  G A  SA +++  P  +NA
Sbjct: 210 MQILEIRGVTRDDLGVYTCMVVNGSGKASMSAELSI--PGLDNA 251



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 12/200 (6%)

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
            IKV + +   +   +    E+C   + ++ +N +G  +A      V  T +D P      
Sbjct: 1306 IKVENGESGSKLTILAARQEHCG-CYTLVVENKLGSRQAQ-----VNLTVVDKPDPPAGT 1359

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKLSIN 1832
                 I + S+ ++W+ S  +GGS +  Y VEI   E K WK           +Q L  +
Sbjct: 1360 PCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPD 1419

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPES 1891
              Y+FR+ A N  GTS P    +   +G+    P +P++ V VS+   +   + +     
Sbjct: 1420 REYKFRVRAVNVYGTSEPSQESELTAVGE---KPEEPKDEVEVSDDDEKEPEVDYRTVTV 1476

Query: 1892 NGGSPITN-YIIEFKTVKGK 1910
            N    +++ Y IE +   GK
Sbjct: 1477 NTEQKVSDVYDIEERLGSGK 1496



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 7/114 (6%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP        + S+ +  SW    +DGG+ +  YN+ I D    +W E+      +  
Sbjct: 1353 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKEL--ATCRSTS 1410

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
            FN++DL  +  Y  R+ A N  G SEP +  E   V  GE     EEP ++ EV
Sbjct: 1411 FNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAV--GE---KPEEPKDEVEV 1459



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 62/246 (25%), Positives = 100/246 (40%), Gaps = 43/246 (17%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI--------- 680
            +G  P F +K +  +V EG  +LL+C++++ P   + W   G+ +   + I         
Sbjct: 1116 QGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRF 1175

Query: 681  SVAIES----DMHMY------------CSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
            SV+IE     D  +Y            CS     +  +  E T      +R  ++SLP V
Sbjct: 1176 SVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPV 1235

Query: 725  L--------------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            L              K  T    PPQ+I+  +   VR GE V L  +V G    T  W K
Sbjct: 1236 LGTESDATVKKKPAPKTPTKAAMPPQIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMK 1295

Query: 771  NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
              K ++    +  ++      +TIL  ++ +  G YTL  EN  G  +    +TV +  +
Sbjct: 1296 FRKQIQESEHIKVENGESGSKLTILAARQ-EHCGCYTLVVENKLGSRQAQVNLTVVDKPD 1354

Query: 828  ENAEPP 833
              A  P
Sbjct: 1355 PPAGTP 1360



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P FSK  +   V EGS    +C++   P+P++ W FK ++ +  E+    I+ D    
Sbjct: 1829 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 1886

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
            CS++ I++V    +  YT  AVN  GEA+    L ++T E+
Sbjct: 1887 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1926



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 27/94 (28%), Positives = 41/94 (43%)

Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
           E P FI   + + VKE  T K   RV   P P +TW+R  + I+       +        
Sbjct: 31  EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFS 90

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           ++ +   E D G Y C ASN +G       +T++
Sbjct: 91  LVIHTVREEDKGKYTCEASNGSGARQVTVELTVE 124



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 42/194 (21%), Positives = 78/194 (40%), Gaps = 13/194 (6%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXX--XXX 1540
            +P     TE  + ++  C   G+P+P V W+ +G  ++  +     YE+           
Sbjct: 407  QPQSQEVTE-GQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLCLLRA 465

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKV---GDEWLVTAVI 1596
                   Y C A N  G+V  S  + + +  +  T  +     K  V   G ++++   +
Sbjct: 466  RTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSV 525

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            +G P P V W  NG  ++    ++I  +   + + I++        YT  A N  G  S 
Sbjct: 526  QGTPAPRVTWLLNGQPIQ--FAHSI-CEAGVAELHIQDALPEDRGTYTCLAENAMGQVSC 582

Query: 1657 EVTLKVYDKPSKPE 1670
              T+ V +K  + E
Sbjct: 583  SATVTVQEKKGEGE 596



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 2/121 (1%)

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            + AE  E   + S         E+    P F    +++ V E    +   ++   P P +
Sbjct: 1803 INAEKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1862

Query: 865  TWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             W+++++ I  S     ++D + N  L+I++V  + D   Y C A NS G+++  A + +
Sbjct: 1863 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELIV 1921

Query: 924  D 924
            +
Sbjct: 1922 E 1922



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYEN 1531
            E++  +P  ++ L+++     E + L C     P   VTW  +GK LKT K    A   +
Sbjct: 1114 ESQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGS 1173

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
            R               YKC+A N  G+ E SC V +
Sbjct: 1174 RFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTV 1209



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 21/78 (26%), Positives = 35/78 (44%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G  W  +  I G PPP+V W K    L+     +++ K    ++ I+ + R     YT
Sbjct: 168  KEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQILEIRGVTRDDLGVYT 227

Query: 1645 IEASNTAGTSSVEVTLKV 1662
                N +G +S+   L +
Sbjct: 228  CMVVNGSGKASMSAELSI 245



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 4/101 (3%)

Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
            S+  S S+TL W     +GGS + +Y +E    + K W ++ T   +     ++++    
Sbjct: 1363 SDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFN--VQDLLPDR 1420

Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
            E  FR+ A N  G S P  SQ   L      P  P   +E+
Sbjct: 1421 EYKFRVRAVNVYGTSEP--SQESELTAVGEKPEEPKDEVEV 1459



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 6/127 (4%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F  KLQD  V E +  +L+ ++ S+  A V W  +G+ +K  K      + G    + 
Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTK-FIVLAQEGSRFSVS 1178

Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131
            I      D G Y C+ ++ +    C+ +VTV +      T+    K  +   +   +  T
Sbjct: 1179 IEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGT 1238

Query: 1132 KGDALVR 1138
            + DA V+
Sbjct: 1239 ESDATVK 1245



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P+V W++ G  + N   + +    + T  + I  ++     KYT EASN +G  
Sbjct: 56   VRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGAR 115

Query: 1655 SVEVTLKVY-DKPSKPEGPVIMR 1676
             V V L V  +   K + PV+ +
Sbjct: 116  QVTVELTVEGNSMKKRDQPVLSK 138



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164
            P     +++ +V +G+ A F+ ++    D  V WFKD   I+ S H Q+  D      L 
Sbjct: 1831 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1890

Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
            I D   DD  +Y+C+    +G + CTA L VE
Sbjct: 1891 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1922



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 3/79 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG-- 1652
            IEG P PEV+W+K+   +   + + I   E  +  + I ++     +KYT +A N+ G  
Sbjct: 1854 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1913

Query: 1653 TSSVEVTLKVYDKPSKPEG 1671
            T + E+ ++  ++    EG
Sbjct: 1914 TCTAELIVETMEEGEGEEG 1932



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 1/90 (1%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            E PP+  T+L    V +G    F  ++T +    V W K    +Q S  + ++     Q 
Sbjct: 153  ECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQI 212

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            L+I     DD G Y+C V N    A ++ E
Sbjct: 213  LEIRGVTRDDLGVYTCMVVNGSGKASMSAE 242



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 21/85 (24%), Positives = 38/85 (44%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++  +  G  + L     + P     W +N K +K  K    + +    S++I+K    D
Sbjct: 1127 QDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPED 1186

Query: 1355 AGIYKLRLENNCGHADVEMNVTILD 1379
             G+YK   +N+ G A+    VT+ D
Sbjct: 1187 RGLYKCVAKNSAGQAECSCQVTVDD 1211



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P   + ++ + V +G +     ++ G P P + W K+++ ++         D D +   I
Sbjct: 1831 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1890

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            +      D+  YT KA NS G A  +A + VE   E   E
Sbjct: 1891 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1930



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 5/103 (4%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P    +LQ+  V +G K   + + ++   A V W  +G  ++ +  I L  +G +  + I
Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSI 1179

Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204
                 +D G Y C      G ++C+  +TV++   +   + PE
Sbjct: 1180 EKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPE 1222


>UniRef50_Q4RH24 Cluster: Chromosome 18 SCAF15072, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 18 SCAF15072, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1065

 Score =  136 bits (330), Expect = 5e-30
 Identities = 187/847 (22%), Positives = 313/847 (36%), Gaps = 56/847 (6%)

Query: 462  LTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK 519
            LT+E      + LM+E  N Y+        E+ + L +            P F+ K    
Sbjct: 120  LTQEVRQPEVKELMEEPGNGYSALQNGACGEE-NGLSLNGDANDTSSDDKPRFLIKPLSL 178

Query: 520  HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPE 576
                G    F C++ G P P++ W +    +     S  F +   D     L I      
Sbjct: 179  RVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISEQDGGWFQLRIYRTRMP 238

Query: 577  DAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI-PPT 635
            D G +TC A N  G A +   L+VEA      S M+                   + PP 
Sbjct: 239  DKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTSRLLPKHRSHKAALEPPV 298

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
               K K   V EG      C +   P+P+I W  K + +  +      I  D   Y + L
Sbjct: 299  DVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVW--KKDGVPLEAGRRHLIFEDREGYYT-L 355

Query: 696  KITNVKKFQEGTYTVVAVNREG---EASLPIVLKI-----KTGEKEPPQVIEPL-KSMIV 746
            K+   K+   G Y   A N  G   +   P+  ++      T E+    ++  L + + V
Sbjct: 356  KVLYCKEKDTGLYVCAASNALGNHAQRCAPVRQRLGWKVQATLERRRGPIVRKLPRKLEV 415

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVY 803
             +GE+ +   +V  N    I W K+   +  +     KS G TH +  +     +D GV 
Sbjct: 416  MEGENAMFCVEVE-NDEEEIHWFKDGLQLHEMHQVILKSFGKTHILVFVNVAH-RDSGVV 473

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            T  A  S   +      +   P    AE  + ++R           +   A    +P  +
Sbjct: 474  TFVAGRSRTSSRLKVRASRHCPPICPAEATMDVDR-------PNSALLAWAPAPNSPTST 526

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK--CVASNSAGKSSHGA-R 920
             + +        S+   + F  E         D     G+Y+      N  G+S H    
Sbjct: 527  RSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVCCINKYGRSGHVEFP 586

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG- 979
              + +     +++  KS E  EG+      Q S T++  W+ N  ++       I Q   
Sbjct: 587  KVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAGTWFLNSAQLQPGGRFSIEQRHT 646

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE----VKEKDVAI 1035
            +            D   +  I      S  L V+    +F   L D +    V+  D  +
Sbjct: 647  KHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVRPVEVKF-SPLSDTDGNKRVETGDAIV 705

Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
            L  E++   A V W +DG+ +    +  + +  G +R++ I++      G Y+C    + 
Sbjct: 706  LYCEVSHPFAQVSWFKDGKELL-MTDDLNIQSEGKMRRVVIQSADASHAGVYTCETSGDI 764

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL----TKGDALVRWFKDGSEIQFSNH 1151
                V V   PP     +  ++++K +     + L    +  DA V W+KDG EI  S +
Sbjct: 765  IRYNVEVAG-PPVEFCPVPEEELHKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSEN 823

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP-- 1209
            + L  DG  ++L I   D  DAG Y+C  GN+     + +   ++  +   P  ++V   
Sbjct: 824  VTLQADGTMRRLIIRSADTSDAGSYTCRAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPK 883

Query: 1210 --------ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
                     + D  L  E+   +  V WYK    +E++    LIS+   R L I   T +
Sbjct: 884  DDVVMERYVSEDIQLQCELSRSSGKVRWYKDGQPVEESPNLQLISEGPYRRLSILTGTVN 943

Query: 1262 DQCEYTC 1268
            D  EY C
Sbjct: 944  DGGEYVC 950



 Score =  119 bits (287), Expect = 8e-25
 Identities = 153/708 (21%), Positives = 262/708 (37%), Gaps = 57/708 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+ V K +     +G   +F C V G P+P+I W +    ++  +   ++ D +   TL 
Sbjct: 297  PVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGRRHLIFEDREGYYTLK 356

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            +     +D G + C A NA               L +H                   +  
Sbjct: 357  VLYCKEKDTGLYVCAASNA---------------LGNHAQRCAPVRQRLGWKVQATLERR 401

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
             G  P   K P+   V EG + +  C  V   E +I W   G ++     + +      H
Sbjct: 402  RG--PIVRKLPRKLEVMEGENAMF-CVEVENDEEEIHWFKDGLQLHEMHQVILKSFGKTH 458

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                +L   NV     G  T VA    G +     LK++     PP +     +M V + 
Sbjct: 459  ----ILVFVNVAHRDSGVVTFVA----GRSRTSSRLKVRASRHCPP-ICPAEATMDVDRP 509

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-----DGDTHSITILKPKKVKDEGVYT 804
             S +L+     N  PT T       ++ + ++        +T +   +    V+ EG Y 
Sbjct: 510  NSALLAWAPAPNS-PTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYR 568

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
             +         +  V   E P   +  P P   N  +   V E        +++      
Sbjct: 569  FRVCCINKYGRSGHV---EFPKVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG- 624

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             TW+ N+  + P    +         LVI       D  +   +A+     +    R  +
Sbjct: 625  -TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVR-PV 682

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXX 982
            +V K + +     +   E G  ++L C+ SH  +   W+ + KE+   D   I  EG+  
Sbjct: 683  EV-KFSPLSDTDGNKRVETGDAIVLYCEVSHPFAQVSWFKDGKELLMTDDLNIQSEGKMR 741

Query: 983  XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVK---EKDVAILEVE 1039
                        GV  C          + V     EF    ++   K   E D  +L   
Sbjct: 742  RVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLLCH 801

Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            +++E A+V W +DG  I P +N    +  G +R+L IR+    D G Y+C   + S    
Sbjct: 802  VSAEDAEVTWYKDGCEIHPSEN-VTLQADGTMRRLIIRSADTSDAGSYTCRAGNNSMEFS 860

Query: 1100 VTVV--------ELPPEIITRLQNQKVNK---GNKATFEIELTKGDALVRWFKDGSEIQF 1148
            V +           PP +I   ++  V +         + EL++    VRW+KDG  ++ 
Sbjct: 861  VNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSSGKVRWYKDGQPVEE 920

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
            S ++QL  +G  ++L I    ++D GEY CE         LTV++P +
Sbjct: 921  SPNLQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKDPPV 968



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 179/865 (20%), Positives = 334/865 (38%), Gaps = 87/865 (10%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-------PTK 781
            + + +P  +I+PL S+ V +GE    S ++ G P P + W K+ K +  +        ++
Sbjct: 164  SSDDKPRFLIKPL-SLRVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISE 222

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA----------- 830
             DG    + I + + + D+GVYT +A N  G A   AV+ VE   E  A           
Sbjct: 223  QDGGWFQLRIYRTR-MPDKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTS 281

Query: 831  -------------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
                         EPP+ +++ ++  V E    K    VT  P P I W ++   +    
Sbjct: 282  RLLPKHRSHKAALEPPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGR 341

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH---------GARV--TIDVE 926
                  D E    +      E D+G Y C ASN+ G  +          G +V  T++  
Sbjct: 342  RHLIFEDREGYYTLKVLYCKEKDTGLYVCAASNALGNHAQRCAPVRQRLGWKVQATLERR 401

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQE-GRXXXX 984
            +   V+ L +  E  EG+  +   +  +      W+ +  ++  M H+ I++  G+    
Sbjct: 402  RGPIVRKLPRKLEVMEGENAMFCVEVENDEEEIHWFKDGLQLHEM-HQVILKSFGKTHIL 460

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKET--IPEFIRKLQDFEVKEKDVAILE--VEI 1040
                    D GV+  +     TS+ L V+ +   P         +V   + A+L      
Sbjct: 461  VFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEATMDVDRPNSALLAWAPAP 520

Query: 1041 NSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS---CILRDESC 1096
            NS T+   ++  + + +  ++    F          +    V  EG Y    C +     
Sbjct: 521  NSPTSTRSIFVVEMQEVGSQEWLKCFTSET-ATSAEVTGDGVQCEGNYRFRVCCINKYGR 579

Query: 1097 TAEVT---VVELPP--EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151
            +  V    VV L P  +I   L++ +V +G  A F I+L+   A   WF + +++Q    
Sbjct: 580  SGHVEFPKVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAGT-WFLNSAQLQPGGR 638

Query: 1152 IQLTIDGKKQKLKIYDCDL-DDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVP 1209
              +     K  L I+   + +D  E +      + +A L V    + F+ L   +     
Sbjct: 639  FSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVRPVEVKFSPLSDTDGNKRV 698

Query: 1210 ANTDAY-LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
               DA  L  E+      V+W+K    +  T+   + S+ K R ++I+         YTC
Sbjct: 699  ETGDAIVLYCEVSHPFAQVSWFKDGKELLMTDDLNIQSEGKMRRVVIQSADASHAGVYTC 758

Query: 1269 VLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
                +    +  VEV    VEF P  V  E  ++     D  +L+ + +       W  +
Sbjct: 759  ET--SGDIIRYNVEVAGPPVEFCP--VPEEELHKSSMELDPVVLLCHVSAEDAEVTWYKD 814

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
               I   ++     D     L I+  + +DAG Y  R  NN    +  +N+   +  S  
Sbjct: 815  GCEIHPSENVTLQADGTMRRLIIRSADTSDAGSYTCRAGNN--SMEFSVNIRGGNVASSN 872

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444
             +P ++ ++     +     E   +  I       +      W       +   ++Q L 
Sbjct: 873  TEPPVMIVEPKDDVVM----ERYVSEDIQLQCELSRSSGKVRWYKDGQPVEESPNLQ-LI 927

Query: 1445 TNSSYRFRAYAVNEVD-----ISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNED 1498
            +   YR  +     V+     + ++   + ++++ +K+  ++  +  +    +T    E 
Sbjct: 928  SEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKDPPVRIISPSESELELTHVAPER 987

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523
            +EL+C    V  P V W+RDG ++K
Sbjct: 988  LELSCEISKVEAP-VRWFRDGLEVK 1011



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 104/466 (22%), Positives = 191/466 (40%), Gaps = 41/466 (8%)

Query: 705  EGTYT--VVAVN---REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            EG Y   V  +N   R G    P V+ +  G    P++   LKS  V +GE    S Q+ 
Sbjct: 564  EGNYRFRVCCINKYGRSGHVEFPKVVHLVPG----PKIQNCLKSCEVAEGEDAHFSIQL- 618

Query: 760  GNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
             +     TW  N+   +P      +     HS+ I +    +D+   T  A    G+ + 
Sbjct: 619  -STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIAN---GVRD- 673

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            SA + V  P E    P    +  + +   +   I L   V+ +P   ++W+++ + +  +
Sbjct: 674  SAPLHVR-PVEVKFSPLSDTDGNKRVETGD--AIVLYCEVS-HPFAQVSWFKDGKELLMT 729

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            + +    +G+   +VI + D+   +G Y C  S    +  +   V     +   V   + 
Sbjct: 730  DDLNIQSEGKMRRVVIQSADAS-HAGVYTCETSGDIIR--YNVEVAGPPVEFCPVPEEEL 786

Query: 937  SYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
               + E   V+L C  S       WY +  EI   ++  +  +G             D G
Sbjct: 787  HKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 846

Query: 996  VIKCIVKDQETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAI---LEVEINSET 1044
               C   +      + ++           P  I + +D  V E+ V+    L+ E++  +
Sbjct: 847  SYTCRAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSS 906

Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
              V W +DG+ ++   N       G  R+L I   +V+D GEY C    +S   ++TV +
Sbjct: 907  GKVRWYKDGQPVEESPN-LQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKD 965

Query: 1105 LPPEIITRLQNQ-KVNKGNKATFEI--ELTKGDALVRWFKDGSEIQ 1147
             P  II+  +++ ++        E+  E++K +A VRWF+DG E++
Sbjct: 966  PPVRIISPSESELELTHVAPERLELSCEISKVEAPVRWFRDGLEVK 1011



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 80/382 (20%), Positives = 155/382 (40%), Gaps = 26/382 (6%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS-SSINI 1399
            K+  L    V + D+G+       +   + +++  +    P  P +   +++D  +S  +
Sbjct: 456  KTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEAT-MDVDRPNSALL 514

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAV 1456
             W    N+  ST   +VVE QE+ + EW+     +  T  + +   ++   +YRFR   +
Sbjct: 515  AWAPAPNSPTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVCCI 574

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED----IELTCIFGGVPQPK 1512
            N+      S   E+ KV+    +  P ++  LK+      ED    I+L+    G     
Sbjct: 575  NKYG---RSGHVEFPKVVH--LVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG----- 624

Query: 1513 VTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQQK 1570
             TW+ +  +L+   + + E R                K  + F  +G V  S  + ++  
Sbjct: 625  -TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANG-VRDSAPLHVRPV 682

Query: 1571 PV--ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
             V    +S+ D  ++ + GD  ++   +   P  +V W+K+G +L    + NI ++ K  
Sbjct: 683  EVKFSPLSDTDGNKRVETGDAIVLYCEVSH-PFAQVSWFKDGKELLMTDDLNIQSEGKMR 741

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             + I+    SH+  YT E S      +VEV     +    PE  +    +  + V +   
Sbjct: 742  RVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLLCH 801

Query: 1689 PPLDDGGLELTKYAIEKHEPDN 1710
               +D  +   K   E H  +N
Sbjct: 802  VSAEDAEVTWYKDGCEIHPSEN 823



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 51/225 (22%), Positives = 97/225 (43%), Gaps = 20/225 (8%)

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            ++L C  V+  + ++ W   G EI P EN+++  +  M      L I +      G+YT 
Sbjct: 796  VVLLCH-VSAEDAEVTWYKDGCEIHPSENVTLQADGTMRR----LIIRSADTSDAGSYTC 850

Query: 711  VAVNREGEASLPI-VLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQV-VGNPRPTIT 767
             A N   E S+ I    + +   EPP  ++EP   +++ +  S  +  Q  +      + 
Sbjct: 851  RAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSSGKVR 910

Query: 768  WCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            W K+ +PV+  P     S+G    ++IL    V D G Y  +++      +    +TV++
Sbjct: 911  WYKDGQPVEESPNLQLISEGPYRRLSIL-TGTVNDGGEYVCESDGDSVFFQ----LTVKD 965

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
            P      P        E+T      ++L   +++   P + W+R+
Sbjct: 966  PPVRIISPS---ESELELTHVAPERLELSCEISKVEAP-VRWFRD 1006


>UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscle;
           n=10; Euteleostomi|Rep: Myosin light chain kinase,
           smooth muscle - Gallus gallus (Chicken)
          Length = 1906

 Score =  136 bits (330), Expect = 5e-30
 Identities = 101/367 (27%), Positives = 166/367 (45%), Gaps = 27/367 (7%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           GIPP F  +P++    EG +I  + ++   P+PD+ W  +G  I   E I +  E   H 
Sbjct: 426 GIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTH- 484

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQVIEPLKSMIVRQ 748
            C  LK   +     G+Y+  A N  G+ S   +L +K    E+  P     LK   V +
Sbjct: 485 -CLWLKKACLG--DSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSE 541

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
           G+  +L   V G P P ITW  N +P++   +  +     +T+ +    +D+G+YT  AE
Sbjct: 542 GQDFVLQCYVGGVPVPEITWLLNEQPIQYAHSTFEAGVAKLTV-QDALPEDDGIYTCLAE 600

Query: 809 NSEGIAETSAVITV-EEPTEENAE-----------PPLFINRFQEITVKEKGTIKLVARV 856
           N+ G A  SA +TV E+ + + AE            P+F+    ++ V +   + +   V
Sbjct: 601 NNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEV 660

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
           + NP P I W  N + I  +E       G    L I  V  E D+G Y C A N  G++ 
Sbjct: 661 SANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPE-DTGKYTCEAWNELGETQ 719

Query: 917 HGARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGM 970
             A +T+    D  +  F+    +S     G+ V++ C  +     +  W+ + +EI+  
Sbjct: 720 TQATLTVQEPQDGIQPWFISK-PRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPG 778

Query: 971 DHREIIQ 977
              EI+Q
Sbjct: 779 TGCEILQ 785



 Score =  134 bits (325), Expect = 2e-29
 Identities = 109/432 (25%), Positives = 194/432 (44%), Gaps = 56/432 (12%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           E   + P F  + +     +G  ++F+ +V G P+P + WF++   IK  +  Q+ Y++D
Sbjct: 423 EPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQI-YEED 481

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
               L +++    D+G+++C A N  G  S++  L V+ P                    
Sbjct: 482 GTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPK------------------- 522

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                +E + P FS   K   V EG D +L+C +  +P P+I WL        ++ I  A
Sbjct: 523 -----VEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLN------EQPIQYA 571

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE-------- 733
             S      + L + +     +G YT +A N  G A  S  + +K K   K+        
Sbjct: 572 -HSTFEAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAK 630

Query: 734 -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGD 785
                 P  ++ L  + V  G  VI++ +V  NP P I W  N K ++       +  G+
Sbjct: 631 LNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGN 690

Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
            +S+ I +    +D G YT +A N  G  +T A +TV+EP  ++   P FI++ + +T  
Sbjct: 691 EYSLYI-QEVFPEDTGKYTCEAWNELGETQTQATLTVQEP--QDGIQPWFISKPRSVTAA 747

Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDY 904
               + +   +  +P P++ W+++ + I+P  T  +    E+I  L++ NV S   +G Y
Sbjct: 748 AGQNVLISCAIAGDPFPTVHWFKDGQEITPG-TGCEILQNEDIFTLILRNVQSR-HAGQY 805

Query: 905 KCVASNSAGKSS 916
           +    N  G+ S
Sbjct: 806 EIQLRNQVGECS 817



 Score =  107 bits (257), Expect = 3e-21
 Identities = 95/369 (25%), Positives = 156/369 (42%), Gaps = 27/369 (7%)

Query: 468 WVPAQYLMDENNYT-QYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGST 526
           W+    L D  +Y+      +       L   ++P  EE  +AP F   L+     +G  
Sbjct: 487 WLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEE--VAPCFSSVLKGCTVSEGQD 544

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
              +C V G P P+ITW       +P Q     ++   VA L +++  PED G +TC+A+
Sbjct: 545 FVLQCYVGGVPVPEITWLLNE---QPIQYAHSTFEA-GVAKLTVQDALPEDDGIYTCLAE 600

Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
           N AG AS + ++ V+   S   +E T             A + +   P F K      V 
Sbjct: 601 NNAGRASCSAQVTVKEKKSSKKAEGT-----------QAAKLNKTFAPIFLKGLTDLKVM 649

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           +GS +++   + A P P+I WL  G+EI   E+     E   + Y   L I  V     G
Sbjct: 650 DGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFH--FEKKGNEYS--LYIQEVFPEDTG 705

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
            YT  A N  GE      L ++  +    P  I   +S+    G++V++S  + G+P PT
Sbjct: 706 KYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPT 765

Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
           + W K+ +   P        + D  ++ IL+  + +  G Y ++  N  G       + +
Sbjct: 766 VHWFKDGQEITPGTGCEILQNEDIFTL-ILRNVQSRHAGQYEIQLRNQVGECSCQVSLML 824

Query: 823 EEPTEENAE 831
            E +   AE
Sbjct: 825 RESSASRAE 833



 Score =  100 bits (239), Expect = 5e-19
 Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 1/188 (0%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+I  +  + +++ G  V L             W+   K I++ ++ K      S+ LT
Sbjct: 1224 PPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLT 1283

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405
            I   +    G Y L +EN  G    ++N+T++DKP PP G P   +I SSS+ + W    
Sbjct: 1284 ISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1343

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              G S +  Y VE       +W  +     T  ++Q+L+ +  Y+FR  A N   IS+ S
Sbjct: 1344 YDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDLQADREYKFRVRAANVYGISEPS 1403

Query: 1466 ETTEYYKV 1473
            + +E  KV
Sbjct: 1404 QESEVVKV 1411



 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 65/228 (28%), Positives = 97/228 (42%), Gaps = 8/228 (3%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP F    R      G+T +FE +V GYP PQITW+R    +     + + +    + +L
Sbjct: 27  APAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSL 86

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA----PLSDHGSEMTVXXXXXXXXXXX 624
           VI+ V   D+G +TC A N  G    T EL VE       S   S  T            
Sbjct: 87  VIKGVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPVEH 146

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
              I    PP F+ KP    V EG      C++   P+P + W      +  +E  ++  
Sbjct: 147 RPSIWGESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNMFE 206

Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
           ++ +      L+I NV+    G YT   VN  G+AS+   L ++  +K
Sbjct: 207 KTGI----QYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQGPDK 250



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 101/433 (23%), Positives = 172/433 (39%), Gaps = 53/433 (12%)

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            + EN  G+ ++      EE  E    PP F +R Q +   E   IK  ++V+  P P + 
Sbjct: 406  ETENRAGVRKS----VKEEKREPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVE 461

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W++    I   E I Q ++ +    +        DSG Y C A N  G++S    +T+  
Sbjct: 462  WFKEGVPIKTGEGI-QIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKR 520

Query: 926  EKVTFV----KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979
             KV  V      + K     EG+  +L+C        +  W  N++ I    +     E 
Sbjct: 521  PKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQ---YAHSTFEA 577

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET------------------IP 1017
                         D G+  C+ ++       S  + VKE                    P
Sbjct: 578  GVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAP 637

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
             F++ L D +V +    I+ VE+++    +++W  +G+ I+  ++ + FEK+G+   LYI
Sbjct: 638  IFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETED-FHFEKKGNEYSLYI 696

Query: 1077 RNTSVHDEGEYSC----ILRDESCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFEI 1128
            +     D G+Y+C     L +    A +TV E    + P  I++ ++     G       
Sbjct: 697  QEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISC 756

Query: 1129 ELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGN 1182
             +  GD    V WFKDG EI      ++  +     L + +     AG+Y      +VG 
Sbjct: 757  AIA-GDPFPTVHWFKDGQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGE 815

Query: 1183 SKCTAILTVEEPS 1195
              C   L + E S
Sbjct: 816  CSCQVSLMLRESS 828



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 4/189 (2%)

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P IT   ED  +K + G+   + A + G  P    W K   +++ ++   I   E +S +
Sbjct: 1225 PQITQFPED--RKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKL 1282

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690
             I   K+ H   YT+   N  G+   +V L V DKP  P G     +I   S+T+ W   
Sbjct: 1283 TISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1342

Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
              DGG  +  Y +E     +N+W  +        ++ +Q L  + EY FRV A N  G S
Sbjct: 1343 SYDGGSAVQSYTVEIWNSVDNKWTDLTTCRS--TSFNVQDLQADREYKFRVRAANVYGIS 1400

Query: 1751 EALESEPIV 1759
            E  +   +V
Sbjct: 1401 EPSQESEVV 1409



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 38/113 (33%), Positives = 67/113 (59%), Gaps = 1/113 (0%)

Query: 490  EKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
            +K++    F +  +EE+  + P F + +      +GS  +F+C++EGYP P++ W++   
Sbjct: 1773 DKVENEDAFLEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQ 1832

Query: 549  IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             +K S+ FQ+ YD++   +L I EV  +D   +TC A N+ G A+ T EL+VE
Sbjct: 1833 PVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEATCTAELLVE 1885



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 24/220 (10%)

Query: 1467 TTEYYKVIKETKIQ--SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
            +T +   +K  K++  +P     LK  T    +D  L C  GGVP P++TW  + + ++ 
Sbjct: 511  STSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQY 570

Query: 1525 AKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQK------------- 1570
            A +T+E                  Y C+A N+ G    S  V +++K             
Sbjct: 571  AHSTFEAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAK 630

Query: 1571 ------PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
                  P+      D+K     G + ++T  +   P PE+IW  NG +++  ++++   K
Sbjct: 631  LNKTFAPIFLKGLTDLKVMD--GSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKK 688

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
                 + I+E+    + KYT EA N  G +  + TL V +
Sbjct: 689  GNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQE 728



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 25/267 (9%)

Query: 488  LNEKIDKLPVFEKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
            + +K +  P   KPT    +  AP F EKL+     DG  +  +C++   P   ++W   
Sbjct: 1061 IGKKAENKPAASKPTPPPSKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLD 1120

Query: 547  TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----- 601
            +  IK S+   +   +  + +L I +V PED G + C+A+NAAG A    +++VE     
Sbjct: 1121 SKAIKSSKSI-VISQEGTLCSLTIEKVMPEDGGEYKCIAENAAGKAECACKVLVEDTSST 1179

Query: 602  ---APLSDHGSEMTVXXXXXXXXXXXXADILE----------GIPPTFSKKPKAQYVDEG 648
                P      +               A + +            PP  ++ P+ + V  G
Sbjct: 1180 KAAKPAEKKTKKPKTTLPPVLSTESSEATVKKKPAPKTPPKAATPPQITQFPEDRKVRAG 1239

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
              + L  ++V        W+   ++I   EN  + IE+  +   S L I++ K+   G Y
Sbjct: 1240 ESVELFAKVVGTAPITCTWMKFRKQI--QENEYIKIENAEN--SSKLTISSTKQEHCGCY 1295

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPP 735
            T+V  N+ G     + L +   + +PP
Sbjct: 1296 TLVVENKLGSRQAQVNLTV-VDKPDPP 1321



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 89/411 (21%), Positives = 157/411 (38%), Gaps = 27/411 (6%)

Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
            KS  + K E +  PP+     +      G ++         P+P+ EW      IK  + 
Sbjct: 415  KSVKEEKREPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEG 474

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNI 1389
             +   +  +  L +KK    D+G Y     N  G       +T+  +P      P   ++
Sbjct: 475  IQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTV-KRPKVEEVAPCFSSV 533

Query: 1390 LEIDSSS-----INICW----DEPENTG--NSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438
            L+  + S     +  C+      PE T   N   I Y     E    + ++V++      
Sbjct: 534  LKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQYAHSTFEAGVAK-LTVQDALPEDD 592

Query: 1439 SIQN-LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
             I   L  N++ R    A   V    +S+  E  +  K  K  +P   K L ++      
Sbjct: 593  GIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGS 652

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE---NRXXXXXXXXXXXXXXXYKCIAF 1553
             + +T      P P++ W  +GK+++ T    +E   N                Y C A+
Sbjct: 653  QVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAW 712

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKN 1609
            N+ GE +T   + +Q+ P   I    I +   V    G   L++  I G P P V W+K+
Sbjct: 713  NELGETQTQATLTVQE-PQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKD 771

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            G ++       I   E    + ++ ++  H+ +Y I+  N  G  S +V+L
Sbjct: 772  GQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSL 822



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 72/324 (22%), Positives = 128/324 (39%), Gaps = 34/324 (10%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL------ 1279
            DV W+K+   I+  E   +  +     L ++K    D   Y+C   + +  T        
Sbjct: 459  DVEWFKEGVPIKTGEGIQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTV 518

Query: 1280 -KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
             + +V E  P      +   +  G D  L       P P   W++N + I+    T    
Sbjct: 519  KRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQYAHST---F 575

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDSSS 1396
            ++  A LT++     D GIY    ENN G A     VT+ +K S          +++ + 
Sbjct: 576  EAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTF 635

Query: 1397 INI----CWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQNLKTNSSYRF 1451
              I      D     G+  I+   V         W+ + K I +T+      K N    +
Sbjct: 636  APIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGN---EY 692

Query: 1452 RAYAVNEVDISDASE-TTEYYKVIKETKIQSP-TVEKPL-----------KNITTEPNED 1498
              Y + EV   D  + T E +  + ET+ Q+  TV++P            +++T    ++
Sbjct: 693  SLY-IQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQN 751

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL 1522
            + ++C   G P P V W++DG+++
Sbjct: 752  VLISCAIAGDPFPTVHWFKDGQEI 775



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 96/461 (20%), Positives = 175/461 (37%), Gaps = 38/461 (8%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286
            VTW K    ++  E+F +      + L I+     D   YTC ++++     +  E+   
Sbjct: 187  VTWTKGDIHLQQNERFNMFEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQ 246

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             P   D   +         TL    +A    + +   ++ I K+ K T   +  ++    
Sbjct: 247  GPDKTDTHAQPLCMPPKPTTLAT--KAIENSDFKQATSNGIAKELKSTSTELMVETKDRL 304

Query: 1347 IKKVENTDAGIYKLR-LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI----CW 1401
              K E      Y  R  ++     + E N   L +      P +L+  SS+I +      
Sbjct: 305  SAKKET----FYTSREAKDGKQGQNQEANAVPLQESRGTKGPQVLQKTSSTITLQAVKAQ 360

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
             EP+    +T I      Q  D    +     T TQ +  +L    S R R    N   +
Sbjct: 361  PEPKAEPQTTFIR-----QAEDRKRTVQPLMTTTTQEN-PSLTGQVSPRSRE-TENRAGV 413

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
              + +  +     +E     P  E   +++     ++I+      G P+P V W+++G  
Sbjct: 414  RKSVKEEK-----REPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVP 468

Query: 1522 LKTAKA--TYENRXX--XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577
            +KT +    YE                   Y C AFN  G+  TS ++ +++  V  ++ 
Sbjct: 469  IKTGEGIQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAP 528

Query: 1578 --EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRI 1632
                + +   V  G ++++   + G+P PE+ W  N    E   +Y  +T E   + + +
Sbjct: 529  CFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLN----EQPIQYAHSTFEAGVAKLTV 584

Query: 1633 KELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEG 1671
            ++        YT  A N AG  + S +VT+K      K EG
Sbjct: 585  QDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEG 625



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 11/152 (7%)

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
            V D G+   KAEN    ++ +       P       P F  + Q+  V +   + L  R+
Sbjct: 1055 VVDGGIIGKKAENKPAASKPT-------PPPSKGTAPSFTEKLQDAKVADGEKLVLQCRI 1107

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            + +P  S++W  +++ I  S++I  + +G    L I  V  E D G+YKC+A N+AGK+ 
Sbjct: 1108 SSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTIEKVMPE-DGGEYKCIAENAAGKAE 1166

Query: 917  HGARVTI-DVEKVTFVKHLQKSYETEEGKTVI 947
               +V + D       K  +K  +T++ KT +
Sbjct: 1167 CACKVLVEDTSSTKAAKPAEK--KTKKPKTTL 1196



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 85/403 (21%), Positives = 164/403 (40%), Gaps = 49/403 (12%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P+F  + Q  E  E      + +++ +   DV W ++G  IK  +    +E+ G    L+
Sbjct: 429  PQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDG-THCLW 487

Query: 1076 IRNTSVHDEGEYSCIL---RDESCTAEVTVVELP------PEIITRLQNQKVNKGNKATF 1126
            ++   + D G YSC     R ++ T+ +  V+ P      P   + L+   V++G    F
Sbjct: 488  LKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQD--F 545

Query: 1127 EIELTKGDALV---RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----E 1179
             ++   G   V    W  +   IQ+++    T +    KL + D   +D G Y+C     
Sbjct: 546  VLQCYVGGVPVPEITWLLNEQPIQYAHS---TFEAGVAKLTVQDALPEDDGIYTCLAENN 602

Query: 1180 VGNSKCTAILTVEEPS------------INFTLRLPEFIL------VPANTDAYLTVEIP 1221
             G + C+A +TV+E              +N T   P F+       V   +   +TVE+ 
Sbjct: 603  AGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFA-PIFLKGLTDLKVMDGSQVIMTVEVS 661

Query: 1222 DETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
                 ++ W      I++TE F       + +L I++   +D  +YTC   +    T+ +
Sbjct: 662  ANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQ 721

Query: 1281 VEV-VEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
              + V+ P     P  +   R      G +V +       P P   W  + + I      
Sbjct: 722  ATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGC 781

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            +   +    +L ++ V++  AG Y+++L N  G    ++++ +
Sbjct: 782  EILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSLML 824



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 65/249 (26%), Positives = 102/249 (40%), Gaps = 36/249 (14%)

Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
           G   +V   R  + SL +   +     E P    P +++ V+ G +     +V G P P 
Sbjct: 2   GDVKLVTSTRVSKTSLTLSPSVPA---EAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQ 58

Query: 766 ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETS----- 817
           ITW +N  P+ +      D     I  L  K V+  D G YT +A N  G+ + +     
Sbjct: 59  ITWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGVQEGDSGKYTCEAANDGGVRQVTVELTV 118

Query: 818 ---------------------AVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
                                +V  VE  P+     PP F  +   + V+E  T +   +
Sbjct: 119 EGNSLKKYSLPSSAKTPGGRLSVPPVEHRPSIWGESPPKFATKPNRVVVREGQTGRFSCK 178

Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGK 914
           +T  P P +TW + +  +  +E     F+   I+ L I NV    D+G Y C   NSAGK
Sbjct: 179 ITGRPQPQVTWTKGDIHLQQNERFNM-FEKTGIQYLEIQNVQL-ADAGIYTCTVVNSAGK 236

Query: 915 SSHGARVTI 923
           +S  A +T+
Sbjct: 237 ASVSAELTV 245



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 60/233 (25%), Positives = 99/233 (42%), Gaps = 37/233 (15%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F+  P+   V  G+    E ++   PEP I W   G  + P+ +  V   S   ++  
Sbjct: 28  PAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPL-PEGDHYVVDHSIRGIFSL 86

Query: 694 VLKITNVKKFQEGTYTVVAVNREG----------------EASLPIVLKIKTGE------ 731
           V+K   V++   G YT  A N  G                + SLP   K   G       
Sbjct: 87  VIK--GVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPV 144

Query: 732 --------KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783
                   + PP+       ++VR+G++   S ++ G P+P +TW K +  ++     + 
Sbjct: 145 EHRPSIWGESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNM 204

Query: 784 GDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEP--TEENAEP 832
            +   I  L+ + V+  D G+YT    NS G A  SA +TV+ P  T+ +A+P
Sbjct: 205 FEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQGPDKTDTHAQP 257



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 68/303 (22%), Positives = 123/303 (40%), Gaps = 33/303 (10%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163
            +PP+  +R Q+ + ++G +  F+ +++ K    V WFK+G  I+    IQ+  +     L
Sbjct: 427  IPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTHCL 486

Query: 1164 KIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFIL----VPANTDAY 1215
             +    L D+G YSC      G +  + +LTV+ P +         +L    V    D  
Sbjct: 487  WLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFV 546

Query: 1216 LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272
            L   +    + ++TW   +  I+     T  + V K  L ++    +D   YTC+  +  
Sbjct: 547  LQCYVGGVPVPEITWLLNEQPIQYAHS-TFEAGVAK--LTVQDALPEDDGIYTCLAENNA 603

Query: 1273 AKSTTKLKVEVVE------------------FPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314
             +++   +V V E                  F P  +    + ++  GS V + V+  A 
Sbjct: 604  GRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSAN 663

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P   W+ N K I++ +           SL I++V   D G Y     N  G    +  
Sbjct: 664  PCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQAT 723

Query: 1375 VTI 1377
            +T+
Sbjct: 724  LTV 726



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 46/187 (24%), Positives = 82/187 (43%), Gaps = 9/187 (4%)

Query: 1893 GGSPITNYIIEF-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            G +PIT   ++F K ++   + KI     S  +  I + K++    + +  EN +G S  
Sbjct: 1250 GTAPITCTWMKFRKQIQENEYIKIENAENS-SKLTISSTKQEHCGCYTLVVENKLG-SRQ 1307

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
             +     ++K    P PP        + S+ +  SW    +DGG+ +  Y + I +    
Sbjct: 1308 AQVNLTVVDK----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDN 1363

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071
             W ++      +  FN++DL  +  Y  R+ A N  G+SEP +  E  KV   +     E
Sbjct: 1364 KWTDL--TTCRSTSFNVQDLQADREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKE 1421

Query: 2072 EPGEQTE 2078
            E  E ++
Sbjct: 1422 EEAELSD 1428



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 43/202 (21%), Positives = 81/202 (40%), Gaps = 8/202 (3%)

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
            N +IK+ + +   +        E+C   + ++ +N +G  +A      V  T +D P   
Sbjct: 1268 NEYIKIENAENSSKLTISSTKQEHCG-CYTLVVENKLGSRQAQ-----VNLTVVDKPDPP 1321

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKL 1829
                    I + S+ ++W+ S  +GGS +  Y VEI      KW            +Q L
Sbjct: 1322 AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDL 1381

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
              +  Y+FR+ A N  G S P    + + +G+      +     +S+   +   + +   
Sbjct: 1382 QADREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKEEEAELSDDEGKETEVNYRTV 1441

Query: 1890 ESNGGSPITN-YIIEFKTVKGK 1910
              N    +++ Y IE +   GK
Sbjct: 1442 TINTEQKVSDVYNIEERLGSGK 1463



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 77/364 (21%), Positives = 141/364 (38%), Gaps = 47/364 (12%)

Query: 936  KSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
            +S E  EG+ +  + + S       +W+     I   +  +I +E              D
Sbjct: 436  QSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTHCLWLKKACLGD 495

Query: 994  VGVIKCIVKDQE----TSTMLVVK-----ETIPEFIRKLQDFEVKEKDVAILEVEINS-E 1043
             G   C   +      TS +L VK     E  P F   L+   V E    +L+  +    
Sbjct: 496  SGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVP 555

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAE 1099
              ++ W  + + I+   + ++      + KL +++    D+G Y+C+  +     SC+A+
Sbjct: 556  VPEITWLLNEQPIQYAHSTFE----AGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQ 611

Query: 1100 VTVVE------------------LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWF 1140
            VTV E                    P  +  L + KV  G++    +E++      + W 
Sbjct: 612  VTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWL 671

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196
             +G EIQ +        G +  L I +   +D G+Y+C    E+G ++  A LTV+EP  
Sbjct: 672  HNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQD 731

Query: 1197 N---FTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
                + +  P  +   A  +  ++  I  D    V W+K    I       ++ +    T
Sbjct: 732  GIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGCEILQNEDIFT 791

Query: 1253 LIIR 1256
            LI+R
Sbjct: 792  LILR 795



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 12/178 (6%)

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
           +K   S  +++TS  ++   P    AE P F    + I V+   T +   +V   P P I
Sbjct: 4   VKLVTSTRVSKTSLTLSPSVP----AEAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQI 59

Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           TWYRN   +   +    +     I  LVI  V  E DSG Y C A+N  G       V +
Sbjct: 60  TWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGV-QEGDSGKYTCEAANDGGVRQ--VTVEL 116

Query: 924 DVEKVTFVKH-LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGR 980
            VE  +  K+ L  S +T  G+  +   +   ++   W  +  + +   +R +++EG+
Sbjct: 117 TVEGNSLKKYSLPSSAKTPGGRLSVPPVEHRPSI---WGESPPKFATKPNRVVVREGQ 171



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 20/162 (12%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITI 791
            P   E L+   V  GE ++L  ++  +P  +++W  ++K +   K++    +G   S+TI
Sbjct: 1084 PSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTI 1143

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE--------PTEENAE------PPLFIN 837
             K    +D G Y   AEN+ G AE +  + VE+        P E+  +      PP+   
Sbjct: 1144 EKVMP-EDGGEYKCIAENAAGKAECACKVLVEDTSSTKAAKPAEKKTKKPKTTLPPVLST 1202

Query: 838  RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
               E TVK+K   K   +    P P IT +  +  +   E++
Sbjct: 1203 ESSEATVKKKPAPKTPPKAA-TP-PQITQFPEDRKVRAGESV 1242



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 2/88 (2%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHI 1071
            K T P F  KLQD +V + +  +L+  I+S+  A V W  D + IK  K+     + G +
Sbjct: 1080 KGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKS-IVISQEGTL 1138

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE 1099
              L I      D GEY CI  + +  AE
Sbjct: 1139 CSLTIEKVMPEDGGEYKCIAENAAGKAE 1166



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 4/103 (3%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSIT 790
            PPQ+ +  +   VR GESV L A+VVG    T TW K  K ++    +  ++  ++  +T
Sbjct: 1224 PPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLT 1283

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
            I   K+ +  G YTL  EN  G  +    +TV +  +  A  P
Sbjct: 1284 ISSTKQ-EHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTP 1325



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 3/102 (2%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P F+K      V EGS    +C++   P+P++ W +K ++ V  E+    I+ D    
Sbjct: 1792 VKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMW-YKDDQPV-KESRHFQIDYDEEGN 1849

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
            CS L I+ V    +  YT  AVN  GEA+    L ++T  KE
Sbjct: 1850 CS-LTISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMGKE 1890



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 3/79 (3%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG-- 1652
            IEG P PEV+WYK+   ++  + + I   E+ +  + I E+     +KYT +A N+ G  
Sbjct: 1817 IEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEA 1876

Query: 1653 TSSVEVTLKVYDKPSKPEG 1671
            T + E+ ++   K  + EG
Sbjct: 1877 TCTAELLVETMGKEGEGEG 1895



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 12/135 (8%)

Query: 1828 KLSINTTYQ-----FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
            KL+I++T Q     + +   N++G+     +   +T+     PP+       S+  S S+
Sbjct: 1281 KLTISSTKQEHCGCYTLVVENKLGSRQAQVN---LTVVDKPDPPAGTP--CASDIRSSSL 1335

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            TL W     +GGS + +Y +E        WT + T   +     +++++   E  FR+ A
Sbjct: 1336 TLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFN--VQDLQADREYKFRVRA 1393

Query: 1943 ENTVGVSLPTESQSV 1957
             N  G+S P++   V
Sbjct: 1394 ANVYGISEPSQESEV 1408



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P++ WY+NG+ L     Y +    +    + IK ++   S KYT EA+N  G  
Sbjct: 51   VRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGVQEGDSGKYTCEAANDGGVR 110

Query: 1655 SVEVTLKV 1662
             V V L V
Sbjct: 111  QVTVELTV 118



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 12/141 (8%)

Query: 1254 IIRKCTEDDQ-CEYTCVLLDA-----KSTTKLKVEVVEFPPK------IVDYEREYRIKR 1301
            +++K  ++D+ CE+ C ++D      K+  K        PP         +  ++ ++  
Sbjct: 1038 VVKKEEKNDRKCEHGCAVVDGGIIGKKAENKPAASKPTPPPSKGTAPSFTEKLQDAKVAD 1097

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
            G  + L     + P  +  W ++SK IK  K    S +    SLTI+KV   D G YK  
Sbjct: 1098 GEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTIEKVMPEDGGEYKCI 1157

Query: 1362 LENNCGHADVEMNVTILDKPS 1382
             EN  G A+    V + D  S
Sbjct: 1158 AENAAGKAECACKVLVEDTSS 1178



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 3/105 (2%)

Query: 822  VEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            +EE  EE     P F     ++ V E    +   ++   P P + WY++++ +  S    
Sbjct: 1782 LEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQ 1841

Query: 881  QNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             ++D E N  L I+ V  + D   Y C A NS G+++  A + ++
Sbjct: 1842 IDYDEEGNCSLTISEVCGD-DDAKYTCKAVNSLGEATCTAELLVE 1885



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            I G P P+V W K    L+ ++ +N+  K     + I+ ++ + +  YT    N+AG +S
Sbjct: 179  ITGRPQPQVTWTKGDIHLQQNERFNMFEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKAS 238

Query: 1656 V--EVTLKVYDKPSKPEGPVIM 1675
            V  E+T++  DK      P+ M
Sbjct: 239  VSAELTVQGPDKTDTHAQPLCM 260



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 5/94 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P    +LQ+ KV  G K   +  ++    A V W  D   I+ S  I ++ +G    L I
Sbjct: 1084 PSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTI 1143

Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195
                 +D GEY C      G ++C   + VE+ S
Sbjct: 1144 EKVMPEDGGEYKCIAENAAGKAECACKVLVEDTS 1177



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164
            P     + + +V +G+ A F+ ++    D  V W+KD   ++ S H Q+  D +    L 
Sbjct: 1794 PYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLT 1853

Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
            I +   DD  +Y+C+    +G + CTA L VE
Sbjct: 1854 ISEVCGDDDAKYTCKAVNSLGEATCTAELLVE 1885



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 3/97 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793
            P   + +  M V +G +     ++ G P P + W K+++PVK +   + D D      L 
Sbjct: 1794 PYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLT 1853

Query: 794  PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
              +V   D+  YT KA NS G A  +A + VE   +E
Sbjct: 1854 ISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMGKE 1890



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 1/90 (1%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            E PP+  T+     V +G    F  ++T +    V W K    +Q +    +      Q 
Sbjct: 153  ESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNMFEKTGIQY 212

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            L+I +  L DAG Y+C V NS   A ++ E
Sbjct: 213  LEIQNVQLADAGIYTCTVVNSAGKASVSAE 242



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXX 1536
            +K  +P+  + L++      E + L C     P   V+W  D K +K++K+   ++    
Sbjct: 1079 SKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTL 1138

Query: 1537 XXXXXX----XXXXXYKCIAFNDHGEVETSCVVGIQ 1568
                           YKCIA N  G+ E +C V ++
Sbjct: 1139 CSLTIEKVMPEDGGEYKCIAENAAGKAECACKVLVE 1174


>UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 316

 Score =  136 bits (328), Expect = 8e-30
 Identities = 91/318 (28%), Positives = 149/318 (46%), Gaps = 18/318 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           PIF +K++      G  V+FE QVEG P P +T+ R++  I     + +  +++ +  L 
Sbjct: 1   PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLT 60

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGS-EMTVXXXXXXXXXX 623
           IR   PEDAG + C+A N AG  +S   L VE  L+     D G+ +  V          
Sbjct: 61  IRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTIPQFIDMGTYKCQVRNDLGRTSTS 120

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
              +I+    P F +K     V EG     E R+   P P++ W      I+ ++   + 
Sbjct: 121 AHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIE 180

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQV 737
              +   Y   L +  V +   G Y  +AVN+ G+++    L++         E E P +
Sbjct: 181 SVKETGYYS--LTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETEEPTI 238

Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794
           ++ L+ +   +GE++ +  +V G P PTITW K+         + T  DGD  ++TI + 
Sbjct: 239 LQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTI-RD 297

Query: 795 KKVKDEGVYTLKAENSEG 812
            K+ DEG+Y   A+NS G
Sbjct: 298 VKLGDEGIYRCNAKNSSG 315



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 12/216 (5%)

Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
           GTY     N  G  S    L I    +  P+  E L  + V +G+      +V G P P 
Sbjct: 104 GTYKCQVRNDLGRTSTSAHLNIIVATR--PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161

Query: 766 ITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
           + W   +  +       + +  +   +S+T+ +  + +D G+Y   A N  G +   A +
Sbjct: 162 VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ-EDAGMYKCIAVNKAGKSTCRADL 220

Query: 821 TVEE---PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
            V E     E   E P  + R Q +   E   IK+  RV+  P P+ITW ++  +     
Sbjct: 221 EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDN 280

Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            I   FDG+   L I +V    D G Y+C A NS+G
Sbjct: 281 RIKTYFDGDVCTLTIRDVKLG-DEGIYRCNAKNSSG 315



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 1/87 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           E ++  P  +++L+P  T +G  ++ EC+V G P P ITW +   +       + Y+D D
Sbjct: 230 EFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDGD 289

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAG 590
            V TL IR+V   D G + C AKN++G
Sbjct: 290 -VCTLTIRDVKLGDEGIYRCNAKNSSG 315



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 61/212 (28%), Positives = 86/212 (40%), Gaps = 21/212 (9%)

Query: 993  DVGVIKCIVKDQ--ETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-AD 1046
            D+G  KC V++    TST   + ++  T PEF  KL   EV E D A  EV +      +
Sbjct: 102  DMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161

Query: 1047 VVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVT 1101
            V W      I+   + + +  K      L +      D G Y CI  +++    C A++ 
Sbjct: 162  VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLE 221

Query: 1102 VVELP---------PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNH 1151
            V E           P I+ RLQ     +G     E  ++ K +  + W KDG      N 
Sbjct: 222  VNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNR 281

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            I+   DG    L I D  L D G Y C   NS
Sbjct: 282  IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNS 313



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 18/166 (10%)

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
           D G Y  +  N  G   TSA + +   T      P F  +  ++ V E    K   RV  
Sbjct: 102 DMGTYKCQVRNDLGRTSTSAHLNIIVATR-----PEFKEKLTKVEVTEGDRAKFEVRVKG 156

Query: 859 NPVPSITWYR-NNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSS 916
            P P + WY  +N I+       ++        L +  V  E D+G YKC+A N AGKS+
Sbjct: 157 YPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQE-DAGMYKCIAVNKAGKST 215

Query: 917 HGARVTI---------DVEKVTFVKHLQKSYETEEGKTVILECQTS 953
             A + +         + E+ T ++ LQ   +T EG+ + +EC+ S
Sbjct: 216 CRADLEVNERQFAPEFETEEPTILQRLQ-PVDTIEGEAIKMECRVS 260



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 57/215 (26%), Positives = 84/215 (39%), Gaps = 19/215 (8%)

Query: 899  IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTV 956
            ID G YKC   N  G++S  A + I V      K      E  EG     E +       
Sbjct: 101  IDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYP 160

Query: 957  STKWYHNKKEISGMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCI-VKDQETSTM---L 1010
              +WYH    I   D  EI  ++E              D G+ KCI V     ST    L
Sbjct: 161  EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 220

Query: 1011 VVKET--IPEF-------IRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK 1060
             V E    PEF       +++LQ  +  E +   +E  ++ +    + W +DG ++    
Sbjct: 221  EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDG-LVFLTD 279

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
            N+      G +  L IR+  + DEG Y C  ++ S
Sbjct: 280  NRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSS 314



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 2/125 (1%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            YKC   ND G   TS  + I          +  K +   GD       ++G P PEV WY
Sbjct: 106  YKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWY 165

Query: 1608 KNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
               N++ ++  + I + ++T    + + E+ +  +  Y   A N AG S+    L+V ++
Sbjct: 166  HGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 225

Query: 1666 PSKPE 1670
               PE
Sbjct: 226  QFAPE 230



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 6/172 (3%)

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS--T 1411
            D G YK ++ N+ G      ++ I+    P  K  + +++ +  +    E    G     
Sbjct: 102  DMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161

Query: 1412 IIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + +Y    + +D    E  SVK       ++  +    +  ++  AVN+   S      E
Sbjct: 162  VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLE 221

Query: 1470 YYK--VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
              +     E + + PT+ + L+ + T   E I++ C   G P+P +TW +DG
Sbjct: 222  VNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDG 273



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 13/155 (8%)

Query: 1226 DVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281
            +V WY   + I D ++F +  + +    +L + +  ++D   Y C+ ++   KST +  +
Sbjct: 161  EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 220

Query: 1282 EVVE--FPPKIVDYEREY--RIK-----RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            EV E  F P+    E     R++      G  + +       P+P   W+ +  +     
Sbjct: 221  EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDN 280

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
              K   D    +LTI+ V+  D GIY+   +N+ G
Sbjct: 281  RIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG 315



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 4/96 (4%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIEL 890
           P+F  + + +  +    ++   +V   PVP++T++R +E I      +I +  +G  + L
Sbjct: 1   PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV-L 59

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            I N   E D+G+Y+C+A N AG+ +    + ++ E
Sbjct: 60  TIRNTRPE-DAGEYQCIAVNGAGEVTSKGYLHVEEE 94


>UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome cell
            adhesion molecule; n=1; Danio rerio|Rep: Novel protein
            similar to Down syndrome cell adhesion molecule - Danio
            rerio (Zebrafish) (Brachydanio rerio)
          Length = 1904

 Score =  135 bits (327), Expect = 1e-29
 Identities = 208/1058 (19%), Positives = 399/1058 (37%), Gaps = 109/1058 (10%)

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V+  P I+   + ++V  G++     + +       RW +D S ++  +    ++ G   
Sbjct: 51   VDSAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPLESDSRYHQSVSG--- 107

Query: 1162 KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217
             L I      DAG Y CEV    GN+K    L V++P             V +    + +
Sbjct: 108  -LLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCS 166

Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
            V   DE  D+TWY+    I        I+ +    L++    + D   Y C   + K +T
Sbjct: 167  VTGSDE-FDITWYRNAEKIYQGINVR-ITGINNENLVMEGMAKSDGGAYQCFARNGKMST 224

Query: 1278 KLKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHT 1334
            +  V+VV  +  PKI+    E  +     ++L+   +  P P   W ++   +IK   H 
Sbjct: 225  QDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHR 284

Query: 1335 KPSIDSKSAS----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
               I +        L +   + +D G+Y+    N+ G    +  + +    S     N+ 
Sbjct: 285  MDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKNVT 344

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
             I               G  T I+  +      + +W    N+       +  + N + +
Sbjct: 345  AI--------------AGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNHRQRAFENNGTLK 390

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSP---TVEKP--LKNITTEP---NEDIELT 1502
                 ++ V  SD  E T Y  V  E +I      TV+ P  +++  ++     + + + 
Sbjct: 391  -----LSNVQNSDEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQRVFIP 445

Query: 1503 CIF--GGVPQPKVTWYRDGKKLKTAKA-TYEN---RXXXXXXXXXXXXXXXYKCIAFNDH 1556
            C+   G +P   +TW++DG+ +  +   T +N                   Y CIA N+ 
Sbjct: 446  CVVISGDLPM-SITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEA 504

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLEN 1615
              VE S  + ++  P   +  +D  Q    G    +    +G P P ++W +  G  +  
Sbjct: 505  AAVEHSIQLIVKVPPHFEVQPKD--QDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQ 562

Query: 1616 DKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPS 1667
             +   + +  +  ++      IK +    +  Y  + SN  G   + S+ +T+K+    +
Sbjct: 563  FQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMIT 622

Query: 1668 KPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKH--EPDNNRWI-KVADV-DR 1721
                     +  ++  S T   + P+        ++  E H   PD +R++  V +V D 
Sbjct: 623  SYPNTTRAEQGHMTEMSCTAHGEKPIK------VRWEKESHIINPDMSRYVVTVKEVGDE 676

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
             + T  I          F  IA N  G  + +    ++++   D P           + +
Sbjct: 677  VISTLQILHTVREDSGFFSCIAINSYGEDKGIIQ--LIVQDRPDPPEVEIRE-----VKD 729

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQ 1836
             ++ + W     +G SPI  Y +  K +   W           ++ + +I      +TY 
Sbjct: 730  RTIALRWTMGF-DGNSPITGYDINYKNKSASWASSQMTKDVSPQLNQATIIELHPASTYN 788

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GG 1894
             R++A+N+IG S P    +++TI     PP   P++  +   +S+ + + W  P  +   
Sbjct: 789  IRMFAKNQIGESRP---SNELTITTDEAPPDGAPQDVQLEAISSQGIKVTWKPPHKHLQN 845

Query: 1895 SPITNYII---EFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
              I +Y +   EF T     +  I V   G +    ++N+K+  +   R+ A N  G+  
Sbjct: 846  GLIRSYQVCYREFGTGGSPQYNTINVDTTGDIETLTLDNLKKYTQYEVRVQAANRAGMG- 904

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT-PEWDGGAPLLGYNIAI-RDV 2008
            PT S+ + +     VPS P   +         +  SW   P+      LLGY +    ++
Sbjct: 905  PT-SEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANL 963

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSH 2068
                  E+  +        +  L +   Y I++ A    G  + + S++ +         
Sbjct: 964  PDGELGEIRNITTTKPSLELERLEKYTNYSIQVLAFTRAG--DGVRSEQIYT------RT 1015

Query: 2069 ADEEPGEQTEVXXXXXXXXXXXXXWLREHNMDADIRSY 2106
             ++ PG    V             WL  H ++  IR Y
Sbjct: 1016 KEDVPGPPAGVKAAASTSSVVFVSWLPPHKLNGIIRKY 1053



 Score =  119 bits (286), Expect = 1e-24
 Identities = 201/876 (22%), Positives = 342/876 (39%), Gaps = 93/876 (10%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + L C+    P P   WL         +N  +  +S  H   S L I   +    G+
Sbjct: 69   GHRVELPCKASGHPPPRYRWL--------RDNSPLESDSRYHQSVSGLLIEATRPSDAGS 120

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y     N  G A +   L +K   K    V+ P K +    G  V L   V G+    IT
Sbjct: 121  YVCEVWNSFGNAKVVGRLVVKQPLKA---VVSPRK-VRGSVGSQVSLFCSVTGSDEFDIT 176

Query: 768  WCKN-NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            W +N  K  + +  +  G  +   +++     D G Y   A N +   +    + +E+ T
Sbjct: 177  WYRNAEKIYQGINVRITGINNENLVMEGMAKSDGGAYQCFARNGKMSTQDLVQVVLEDGT 236

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--IISPSETITQNFD 884
                  P  ++ F E  V     I LV  V   P+P++TW  +++  I   +  + +   
Sbjct: 237  ------PKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIIT 290

Query: 885  GENIELVITNVD-SEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             E   L   NV  +++ D G Y+C  +NSAG  S+ AR  I+V     ++ + K+     
Sbjct: 291  TEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQAR--INVRGPASIRPM-KNVTAIA 347

Query: 943  GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            G+   + C+       S KWY +   +   +HR+   E              D G   C 
Sbjct: 348  GRDTYIHCRIIGYPYYSIKWYKD-SNLLPFNHRQRAFENN-GTLKLSNVQNSDEGEYTCY 405

Query: 1001 V---KDQETSTMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEINSE-TADVVWERDGE 1054
            V    +++    + V   +P  I+    Q   + ++ V I  V I+ +    + W +DG 
Sbjct: 406  VLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQR-VFIPCVVISGDLPMSITWHKDGR 464

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIIT 1111
             I         +       L I N S    G Y+CI R+E+   E +   +V++PP    
Sbjct: 465  PINASLG-VTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEV 523

Query: 1112 RLQNQKVNKGNKATFEIELTKGDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQKLK---- 1164
            + ++Q    G   T      KG+ +  + W    G+ +     I L    + Q L+    
Sbjct: 524  QPKDQDGIYGKSVTLNCS-AKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSL 582

Query: 1165 -IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT----DAYLT-- 1217
             I     +DAG Y C+V N     I      S+  T+++P  I    NT      ++T  
Sbjct: 583  LIKHVLEEDAGFYLCKVSNDVGADI----SKSMYLTVKIPAMITSYPNTTRAEQGHMTEM 638

Query: 1218 --VEIPDETLDVTWYKKKSVIE-DTEKFTL----ISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                  ++ + V W K+  +I  D  ++ +    + D    TL I     +D   ++C+ 
Sbjct: 639  SCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIA 698

Query: 1271 LDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFP--QPNDEWIVNSK 1326
            +++    K  ++ +V+  P       E  I+   D T+ + +   F    P   + +N K
Sbjct: 699  INSYGEDKGIIQLIVQDRPD----PPEVEIREVKDRTIALRWTMGFDGNSPITGYDINYK 754

Query: 1327 IIKKCKHTKPSIDSKSASLTIKK---VENTDAGIYKLRL--ENNCGHADVEMNVTILDKP 1381
               K      S  +K  S  + +   +E   A  Y +R+  +N  G +     +TI    
Sbjct: 755  --NKSASWASSQMTKDVSPQLNQATIIELHPASTYNIRMFAKNQIGESRPSNELTITTDE 812

Query: 1382 SPP-GKPNILE---IDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDT-----TEWISVK 1431
            +PP G P  ++   I S  I + W  P ++  N  I  Y V Y+E  T        I+V 
Sbjct: 813  APPDGAPQDVQLEAISSQGIKVTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTINVD 872

Query: 1432 NITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466
                 +T ++ NLK  + Y  R  A N   +   SE
Sbjct: 873  TTGDIETLTLDNLKKYTQYEVRVQAANRAGMGPTSE 908



 Score =  116 bits (279), Expect = 7e-24
 Identities = 168/776 (21%), Positives = 300/776 (38%), Gaps = 72/776 (9%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH---SITI 791
            P +++  +   V  G  V L  +  G+P P   W ++N P+     +SD   H   S  +
Sbjct: 55   PVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPL-----ESDSRYHQSVSGLL 109

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
            ++  +  D G Y  +  NS G A+    + V++P +    P       +++       + 
Sbjct: 110  IEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSP-------RKVRGSVGSQVS 162

Query: 852  LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
            L   VT +    ITWYRN E I   + I     G N E ++    ++ D G Y+C A N 
Sbjct: 163  LFCSVTGSDEFDITWYRNAEKI--YQGINVRITGINNENLVMEGMAKSDGGAYQCFARN- 219

Query: 912  AGKSSHGARVTIDVEKVT---FVKHLQKSYETEEGKTVILECQTSHTVSTKW-YHNKKEI 967
             GK S    V + +E  T        +K     E  +++   + +   +  W   +   I
Sbjct: 220  -GKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVI 278

Query: 968  SGMDHRE---IIQEGR-XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIR 1021
               +HR    I  EG              D GV +C   +   S     +  +  P  IR
Sbjct: 279  KDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIR 338

Query: 1022 KLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
             +++   +  +D  I    I      + W +D  ++     +  FE  G ++   ++N+ 
Sbjct: 339  PMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNHRQRAFENNGTLKLSNVQNS- 397

Query: 1081 VHDEGEYSC-ILRD--ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--A 1135
              DEGEY+C +L D  +     V V    P +I    +Q  + G +      +  GD   
Sbjct: 398  --DEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQRVFIPCVVISGDLPM 455

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195
             + W KDG  I  S  + +        L+I +      G Y+C +  ++  A+    E S
Sbjct: 456  SITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTC-IARNEAAAV----EHS 510

Query: 1196 INFTLRL-PEFILVPANTDAYLTVEIP-------DETLDVTW-YKKKSVIEDTEKFTLIS 1246
            I   +++ P F + P + D      +        +    + W + K + +   +   L S
Sbjct: 511  IQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNS 570

Query: 1247 D-----VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRI 1299
                  ++  +L+I+   E+D   Y C + +      +K     V+ P  I  Y    R 
Sbjct: 571  GSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRA 630

Query: 1300 KRGSDVTLLVDYQAFPQPNDEW-----IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++G    +             W     I+N  + +     K   D   ++L I      D
Sbjct: 631  EQGHMTEMSCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVRED 690

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            +G +     N+ G     + + + D+P PP +  I E+   +I + W    + GNS I  
Sbjct: 691  SGFFSCIAINSYGEDKGIIQLIVQDRPDPP-EVEIREVKDRTIALRWTMGFD-GNSPITG 748

Query: 1415 YVVEYQEIDTTEWIS---VKNITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            Y + Y+   +  W S    K+++    Q +I  L   S+Y  R +A N++  S  S
Sbjct: 749  YDINYKN-KSASWASSQMTKDVSPQLNQATIIELHPASTYNIRMFAKNQIGESRPS 803



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 130/595 (21%), Positives = 232/595 (38%), Gaps = 51/595 (8%)

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            SA + + EP +     P+ ++ F+   V     ++L  + + +P P   W R+N  +   
Sbjct: 42   SARLLLSEPVDS---APVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPLESD 98

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
                Q+  G  IE    +     D+G Y C   NS G +    R+ +       V    +
Sbjct: 99   SRYHQSVSGLLIEATRPS-----DAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVS--PR 151

Query: 937  SYETEEGKTVILECQT--SHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXD 993
                  G  V L C    S      WY N ++I  G++ R  I                D
Sbjct: 152  KVRGSVGSQVSLFCSVTGSDEFDITWYRNAEKIYQGINVR--ITGINNENLVMEGMAKSD 209

Query: 994  VGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVV 1048
             G  +C  ++ + ST     +V+++  P+ +    +  V   +   L   +  +    V 
Sbjct: 210  GGAYQCFARNGKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVT 269

Query: 1049 WERDGE-IIKPKKNKYD--FEKRGHIRK-LYIRNTSVHDEGEYSCILRDE--SCTAEVTV 1102
            W  D + +IK   ++ D      GH+   L + +T V D G Y C   +   S + +  +
Sbjct: 270  WTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARI 329

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ 1161
                P  I  ++N     G        +       ++W+KD + + F NH Q   +    
Sbjct: 330  NVRGPASIRPMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPF-NHRQRAFENNGT 388

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--TVE 1219
             LK+ +    D GEY+C V       I      S++ T+++P  I    +  A +   V 
Sbjct: 389  -LKLSNVQNSDEGEYTCYVLVDPEKQI----HRSVHVTVKVPPLIQHSDSQSASIGQRVF 443

Query: 1220 IP------DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
            IP      D  + +TW+K    I  +   T+ +     +L I   +E     YTC+  + 
Sbjct: 444  IPCVVISGDLPMSITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNE 503

Query: 1274 KSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
             +  +  ++ +V+ PP      ++     G  VTL    +  P P   W  +SK     +
Sbjct: 504  AAAVEHSIQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVW-NHSKGAGVPQ 562

Query: 1333 HTKPSIDS-------KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
                +++S       ++ SL IK V   DAG Y  ++ N+ G AD+  ++ +  K
Sbjct: 563  FQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVG-ADISKSMYLTVK 616



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 132/588 (22%), Positives = 228/588 (38%), Gaps = 69/588 (11%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            GS V   C V G     ITW+R     K  Q   +     N   LV+  +   D G + C
Sbjct: 158  GSQVSLFCSVTGSDEFDITWYRNAE--KIYQGINVRITGINNENLVMEGMAKSDGGAYQC 215

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
             A+N       +T+ +V+  L D   +                     I   FS+K    
Sbjct: 216  FARNG----KMSTQDLVQVVLEDGTPK---------------------ILSAFSEK---- 246

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN--ISVAIESDMHMYCSVLKITNVK 701
             V     I L C +   P P + W    + ++ D N  +   I ++ H+  S L +++ +
Sbjct: 247  VVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHV-LSYLNVSHTQ 305

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
                G Y     N  G  S    + ++      P  I P+K++    G    +  +++G 
Sbjct: 306  VSDGGVYRCTCNNSAGSVSYQARINVR-----GPASIRPMKNVTAIAGRDTYIHCRIIGY 360

Query: 762  PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA-ENSEGIAETSAVI 820
            P  +I W K++  +     +   + +    L   +  DEG YT     + E     S  +
Sbjct: 361  PYYSIKWYKDSNLLPFNHRQRAFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQIHRSVHV 420

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            TV+ P      P +  +  Q  ++ ++  I  V  ++ +   SITW+++   I+ S  +T
Sbjct: 421  TVKVP------PLIQHSDSQSASIGQRVFIPCVV-ISGDLPMSITWHKDGRPINASLGVT 473

Query: 881  -QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
              N D  +  L I+N+ SEI +G Y C+A N A    H  ++ + V     V+   K  +
Sbjct: 474  IDNIDFTS-SLRISNL-SEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQ--PKDQD 529

Query: 940  TEEGKTVILECQT-SHTVST-KWYHNKK------EISGMDHREIIQEGRXXXXXXXXXXX 991
               GK+V L C    + + T  W H+K       +   ++    +Q              
Sbjct: 530  GIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLLIKHVLE 589

Query: 992  XDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQD-FEVKEKDVAILEVEINSE-TAD 1046
             D G   C V +    + S  + +   IP  I    +    ++  +  +    + E    
Sbjct: 590  EDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRAEQGHMTEMSCTAHGEKPIK 649

Query: 1047 VVWERDGEIIKPKKNKY--DFEKRGH--IRKLYIRNTSVHDEGEYSCI 1090
            V WE++  II P  ++Y    ++ G   I  L I +T   D G +SCI
Sbjct: 650  VRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCI 697



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 76/300 (25%), Positives = 122/300 (40%), Gaps = 36/300 (12%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDMHM 690
           +PP       +Q    G  + + C +++   P  I W   G  I    N S+ +  D   
Sbjct: 424 VPPLIQHSD-SQSASIGQRVFIPCVVISGDLPMSITWHKDGRPI----NASLGVTIDNID 478

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
           + S L+I+N+ +   G+YT +A N        I L +K     PP      K      G+
Sbjct: 479 FTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKV----PPHFEVQPKDQDGIYGK 534

Query: 751 SVILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGD--THSITILKPKKVKDEG 801
           SV L+    GNP PTI W  +        +P+ AL + S      +   ++K    +D G
Sbjct: 535 SVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPI-ALNSGSRVQLLENGSLLIKHVLEEDAG 593

Query: 802 VYTLKAENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            Y  K  N  G     S  +TV+ P          I  +   T  E+G +  ++      
Sbjct: 594 FYLCKVSNDVGADISKSMYLTVKIPA--------MITSYPNTTRAEQGHMTEMSCTAHGE 645

Query: 861 VP-SITWYRNNEIISPSET---ITQNFDGENI--ELVITNVDSEIDSGDYKCVASNSAGK 914
            P  + W + + II+P  +   +T    G+ +   L I +   E DSG + C+A NS G+
Sbjct: 646 KPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVRE-DSGFFSCIAINSYGE 704



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 5/102 (4%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           SE    AP+ ++    K    G  V+  C+  G+P P+  W R  +   P +    Y+  
Sbjct: 48  SEPVDSAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNS---PLESDSRYH-- 102

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
            +V+ L+I    P DAG++ C   N+ G A     L+V+ PL
Sbjct: 103 QSVSGLLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPL 144



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 9/144 (6%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            ++TN+ +  + +  VVAV   G  +   ++ ++   K P +++    ++       ++L 
Sbjct: 1078 RLTNLNQNWQYSIWVVAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLP 1137

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKAENSE 811
             + VG+P PTI W K N    A P   DG      +   +++  K +D G Y   A N+ 
Sbjct: 1138 CKAVGDPPPTIKWLKGNNGTPA-PVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNW 1196

Query: 812  GIAETSAVITVE----EPTEENAE 831
            G  E    + V+    + +E+N+E
Sbjct: 1197 GSDEIMLNLQVQGYILQYSEDNSE 1220



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 10/223 (4%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            L++  ++K+   +  V+A  R G+   S  I  + K     PP  ++   S       S 
Sbjct: 981  LELERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVPGPPAGVKAAASTSSVVFVSW 1040

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +   ++ G  R  I +C N  P      ++  D +   +    +     ++ + A  + G
Sbjct: 1041 LPPHKLNGIIRKYIVFCSNPYPTVISEFEAAPDVYFRRLTNLNQNWQYSIWVV-AVTAAG 1099

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYR-NN 870
               TS +ITVE      A+ P  I  F   +T      I L  +   +P P+I W + NN
Sbjct: 1100 RGNTSEIITVEP----QAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLKGNN 1155

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
               +P     +     N   VI  V +E DSG Y+CVASN+ G
Sbjct: 1156 GTPAPVSIDGRRSAHNNGSFVIRTVKAE-DSGYYRCVASNNWG 1197



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY----YDDDNVATLVIREVFPEDAG 579
           G   +  C   G    ++ W +++ II P     +       D+ ++TL I     ED+G
Sbjct: 633 GHMTEMSCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSG 692

Query: 580 TFTCVAKNAAGFASSTTELIVE 601
            F+C+A N+ G      +LIV+
Sbjct: 693 FFSCIAINSYGEDKGIIQLIVQ 714



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 7/167 (4%)

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945
            W   E      +  YI+++     + W    ++  S   + +EN+K      F ++A+N 
Sbjct: 1196 WGSDEIMLNLQVQGYILQYSEDNSEEWGSY-SISPSERSYRLENLKCGTWYKFTLTAQNA 1254

Query: 1946 VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIA 2004
            VG      S+ +  + H     P  A         N          W+ GG P+  + + 
Sbjct: 1255 VGPG--RISEIIEAKTHGK--EPQFAKDHELFSSINSTRVELNLIGWNNGGCPIDSFTLE 1310

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             R V  T W  V K D  T    + DL E   Y +++   N  G +E
Sbjct: 1311 YRPVDTTKWTMV-KRDSLTKSHILYDLQEATWYELQMRVGNSAGTAE 1356



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 6/126 (4%)

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
            R++ L   T Y+F + A+N +G        +  T GK          F    ST   + L
Sbjct: 1235 RLENLKCGTWYKFTLTAQNAVGPGRISEIIEAKTHGKEPQFAKDHELFSSINSTRVELNL 1294

Query: 1885 -KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
              W    +NGG PI ++ +E++ V    WT +V        H + +++E      ++   
Sbjct: 1295 IGW----NNGGCPIDSFTLEYRPVDTTKWT-MVKRDSLTKSHILYDLQEATWYELQMRVG 1349

Query: 1944 NTVGVS 1949
            N+ G +
Sbjct: 1350 NSAGTA 1355



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 6/155 (3%)

Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            L++  Y ++  E ++  W   + +     +Y ++ L     Y F + AQN VG      S
Sbjct: 1205 LQVQGYILQYSEDNSEEWGSYS-ISPSERSYRLENLKCGTWYKFTLTAQNAVGPGRI--S 1261

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWK 1814
            E I  KT    P           I++  V +       NGG PI  + +E +  +  KW 
Sbjct: 1262 EIIEAKTHGKEPQFAKDHELFSSINSTRVELNLI-GWNNGGCPIDSFTLEYRPVDTTKWT 1320

Query: 1815 XXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTS 1848
                     + I   L   T Y+ ++   N  GT+
Sbjct: 1321 MVKRDSLTKSHILYDLQEATWYELQMRVGNSAGTA 1355


>UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscle;
           n=40; Theria|Rep: Myosin light chain kinase, smooth
           muscle - Homo sapiens (Human)
          Length = 1914

 Score =  135 bits (327), Expect = 1e-29
 Identities = 105/431 (24%), Positives = 182/431 (42%), Gaps = 52/431 (12%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           +  S  P F  K + +   +  TV+F C+V G P+P++ WF +   ++  +     Y+D 
Sbjct: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
               L + +    D+GT++C A NA G  S +  L VE                      
Sbjct: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVER--------------------- 506

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
               ++E + P+FS   K   V EG D +L+C +   P P I WL  G+ I    +   A
Sbjct: 507 --LAVME-VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA 563

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL---------------PIVLKIK 728
             +++H       I +      GTYT +A N  G+ S                  +L + 
Sbjct: 564 GVAELH-------IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616

Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD 785
             +   P  ++ L  + V  G  V ++ QV GNP P + W  N   ++       +  G 
Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676

Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
            HS+ I +    +D G YT +A NS G   T AV+TV+EP   +   P FI++ + +T  
Sbjct: 677 QHSLWI-QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP--HDGTQPWFISKPRSVTAS 733

Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
              ++ +   +  +P P++ W R+ + +       +    E++  ++        +G Y+
Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793

Query: 906 CVASNSAGKSS 916
            +  N  G+ S
Sbjct: 794 ILLKNRVGECS 804



 Score =  127 bits (307), Expect = 3e-27
 Identities = 96/366 (26%), Positives = 159/366 (43%), Gaps = 29/366 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYC 692
           P F  KP++Q V E   +   C +  IP+P++AW  +G  +   E +I V  ++  H  C
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGE 750
               +   +    GTY+  A N +G+ S    L+++     +  P     LK   V +G+
Sbjct: 474 ----LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
             +L   V G P P ITW  N +P++   +  +     + I +    +D G YT  AEN+
Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI-QDALPEDHGTYTCLAENA 588

Query: 811 EGIAETSAVITVEEPTEEN----------AEP--PLFINRFQEITVKEKGTIKLVARVTR 858
            G    SA +TV E               ++P  P+F+    ++ V +   + +  +V+ 
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648

Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
           NP P + W  N   I  SE       G    L I  V  E D+G Y C A NSAG+    
Sbjct: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE-DTGTYTCEAWNSAGEVRTQ 707

Query: 919 ARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMD 971
           A +T+    D  +  F+    +S     G++V++ C  +     +  W  + K +     
Sbjct: 708 AVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766

Query: 972 HREIIQ 977
           H E++Q
Sbjct: 767 HFEVLQ 772



 Score =  105 bits (251), Expect = 2e-20
 Identities = 73/246 (29%), Positives = 105/246 (42%), Gaps = 12/246 (4%)

Query: 487 KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           K +  +D   V   P +E    AP F+   R     +G+T +FE +V GYP PQ+TW R 
Sbjct: 14  KTSLSVDPSRVDSMPLTE----APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69

Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
              I     F +        +LVI  V  ED G +TC A N +G    T EL VE   + 
Sbjct: 70  GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAK 129

Query: 607 HGSEMTVXXXXXXXXXXXXADILEGI----PPTFSKKPKAQYVDEGSDILLECRLVAIPE 662
              +  V             +    I    PP F+ K     V EG      C++   P+
Sbjct: 130 QLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQ 189

Query: 663 PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722
           P + WL     + P   +SV+ ++ M     VL+I  V +   G YT + VN  G+AS+ 
Sbjct: 190 PQVTWLKGNVPLQPSARVSVSEKNGM----QVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245

Query: 723 IVLKIK 728
             L I+
Sbjct: 246 AELSIQ 251



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+I+ +  + +++ G  V L             W+   K I++ +H K       + LT
Sbjct: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405
            I        G Y L +EN  G    ++N+T++DKP PP G P   +I SSS+ + W    
Sbjct: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              G S +  Y +E  +     W  +     T  ++Q+L  +  Y+FR  A+N    S+ S
Sbjct: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416

Query: 1466 ETTEYYKVIKETKIQSPTVE 1485
            + +E   V ++ +     VE
Sbjct: 1417 QESELTTVGEKPEEPKDEVE 1436



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 69/241 (28%), Positives = 109/241 (45%), Gaps = 30/241 (12%)

Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
           P +  +  APIF++ L      DGS V    QV G P P++ W      I+ S+DF  + 
Sbjct: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FE 672

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620
                 +L I+EVFPED GT+TC A N+AG   +   L V+ P   H             
Sbjct: 673 QRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---H------------- 716

Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
                    +G  P F  KP++     G  +L+ C +   P P + WL  G+ +  D   
Sbjct: 717 ---------DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767

Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIE 739
              ++++  ++  VLK   V+ +  G Y ++  NR GE S  + L ++ +  +  P+  E
Sbjct: 768 FEVLQNE-DVFTLVLK--KVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGRE 824

Query: 740 P 740
           P
Sbjct: 825 P 825



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 43/117 (36%), Positives = 70/117 (59%), Gaps = 1/117 (0%)

Query: 486  KKLNEKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544
            +KL  + D    F +  +EE+  + P F + +R     +GS  +F+C++EGYP P++ WF
Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 1843

Query: 545  RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +    I+ S+ FQ+ YD+D   +L+I +V  +D   +TC A N+ G A+ T ELIVE
Sbjct: 1844 KDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 3/176 (1%)

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
            QK + G+   +   + G  P    W K   +++  +   +   E  S + I   ++ H  
Sbjct: 1247 QKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCG 1306

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
             YT+   N  G+   +V L V DKP  P G     +I   S+T+ W     DGG  +  Y
Sbjct: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366

Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756
            +IE  +  N  W ++A       ++ +Q L  + EY FRV A N  G SE + ESE
Sbjct: 1367 SIEIWDSANKTWKELATCRS--TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 18/202 (8%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXX 1539
            +P+    LK+      +D  L C   G P P++TW  +G+ ++ A++T E          
Sbjct: 513  APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQD 572

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQ----------------KPVITISNEDIKQ- 1582
                    Y C+A N  G+V  S  V + +                KP   I  + +   
Sbjct: 573  ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K   G +  +T  + G PPPEVIW  NGN+++  ++++   +     + I+E+    +  
Sbjct: 633  KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGT 692

Query: 1643 YTIEASNTAGTSSVEVTLKVYD 1664
            YT EA N+AG    +  L V +
Sbjct: 693  YTCEAWNSAGEVRTQAVLTVQE 714



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 85/402 (21%), Positives = 161/402 (40%), Gaps = 45/402 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P+F  K Q  EVKE        E++     +V W  +G  ++ ++   +  +      L 
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 1076 IRNTSVHDEGEYSCILRDE----SCT-----AEVTVVELPPEIITRLQNQKVNKGNKATF 1126
            +      D G YSC   +     SC+       + V+E+ P   + L++  V +G     
Sbjct: 474  LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533

Query: 1127 EIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EV 1180
            +  + +G  + R  W  +G  IQ++     T +    +L I D   +D G Y+C     +
Sbjct: 534  QCSV-RGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENAL 589

Query: 1181 GNSKCTAILTVEE-----------------PSINFTLRLPEFILVPANTDAYLTVEIP-D 1222
            G   C+A +TV E                 P+    L+    + V   +   +TV++  +
Sbjct: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK-V 1281
               +V W    + I+++E F       + +L I++   +D   YTC   ++    + + V
Sbjct: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709

Query: 1282 EVVEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTK 1335
              V+ P     P  +   R      G  V +       P P   W+ + K + K   H +
Sbjct: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
               +    +L +KKV+   AG Y++ L+N  G    ++++ +
Sbjct: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 91/429 (21%), Positives = 168/429 (39%), Gaps = 47/429 (10%)

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
            S+ +   +A   +    + ++  P F ++ Q   VKE  T+K    V+  P P + W+  
Sbjct: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
               +   E   + ++      +        DSG Y C ASN+ G+ S     T+ VE++ 
Sbjct: 451  GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVS--CSWTLQVERLA 508

Query: 930  FVK------HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEI--------SGMDHR 973
             ++       + K     EG+  +L+C    T   +  W  N + I        +G+   
Sbjct: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAEL 568

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETST----MLVV---KETIPEFIRK 1022
             I                  +G + C     V ++++S     +L V   K T P F++ 
Sbjct: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628

Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
            L D +V +     + V+++     +V+W  +G  I+  ++ + FE+RG    L+I+    
Sbjct: 629  LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED-FHFEQRGTQHSLWIQEVFP 687

Query: 1082 HDEGEYSCIL---RDESCTAEVTVVELP-----PEIITRLQNQKVNKGNKATFEIELTKG 1133
             D G Y+C       E  T  V  V+ P     P  I++ ++   + G        +  G
Sbjct: 688  EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA-G 746

Query: 1134 DAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCT 1186
            D    V W +DG  + + + H ++  +     L +       AG+Y       VG   C 
Sbjct: 747  DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 806

Query: 1187 AILTVEEPS 1195
              L ++  S
Sbjct: 807  VSLMLQNSS 815



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 2/106 (1%)

Query: 503  SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            SE Q  AP F +KL+  H  +G  +  +CQV   P   I W      +K ++ F +   +
Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQE 1149

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDH 607
             ++ ++ I +  PED G + CVAKN AG A  + ++ V +AP S++
Sbjct: 1150 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 47/213 (22%), Positives = 91/213 (42%), Gaps = 8/213 (3%)

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523
            +S  +EY   +  +K  +P   + L ++       + +T    G P P+V W  +G +++
Sbjct: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664

Query: 1524 TAK-ATYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT---IS 1576
             ++   +E R                  Y C A+N  GEV T  V+ +Q+    T     
Sbjct: 665  ESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKEL 1635
            ++       +G   L++  I G P P V W ++G  L  D   + +   E    + +K++
Sbjct: 725  SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            +  H+ +Y I   N  G  S +V+L + +  ++
Sbjct: 785  QPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 33/222 (14%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHS 788
           E P  I P +++ +++G +     +V G P P +TW +N +P+ +    L       T S
Sbjct: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 789 ITILKPKKVKDEGVYTLKAENS------------EG----------IAET-----SAVIT 821
           + I    + +D G YT +A N             EG          +++T     SA   
Sbjct: 91  LVIHAVHE-EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149

Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
              P+     PP F  +   + VKE    +   ++T  P P +TW + N  + PS  ++ 
Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209

Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           +       L I  V+ + D G Y C+  N +GK+S  A ++I
Sbjct: 210 SEKNGMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSI 250



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 40/203 (19%), Positives = 85/203 (41%), Gaps = 12/203 (5%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXX-- 1536
            P  E   ++   + N+ ++  C   G+P+P+V W+ +G  ++  + +   YE+       
Sbjct: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKHKV--GDEWLV 1592
                       Y C A N  G+V  S  + +++  V+ +  S   + +   V  G ++++
Sbjct: 474  LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
               + G P P + W  NG  ++  +    T +   + + I++        YT  A N  G
Sbjct: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIM 1675
              S    + V++K S  +   ++
Sbjct: 591  QVSCSAWVTVHEKKSSRKSEYLL 613



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 48/200 (24%), Positives = 87/200 (43%), Gaps = 12/200 (6%)

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
            +KV + +   +   +    E+C   + ++ +N +G  +A      V  T +D P      
Sbjct: 1284 MKVENSENGSKLTILAARQEHCG-CYTLLVENKLGSRQAQ-----VNLTVVDKPDPPAGT 1337

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSIN 1832
                 I + S+ ++W+ S  +GGS +  Y +EI     K WK           +Q L  +
Sbjct: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPD 1397

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPES 1891
              Y+FR+ A N  GTS P    +  T+G+    P +P++ V VS+   +   + +     
Sbjct: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGE---KPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454

Query: 1892 NGGSPITN-YIIEFKTVKGK 1910
            N    +++ Y IE +   GK
Sbjct: 1455 NTEQKVSDFYDIEERLGSGK 1474



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 7/114 (6%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP        + S+ +  SW    +DGG+ +  Y+I I D     W E+      +  
Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC--RSTS 1388

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
            FN++DL  +H Y  R+ A N  G SEP +  E   V  GE     EEP ++ EV
Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTV--GE---KPEEPKDEVEV 1437



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P   + L+ + V +G+ ++L  QV  +P  TI W  N K +K    +    +G   S++I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTI 850
             K    +D G+Y   A+N  G AE S  +TV++ P  EN + P   +R  + ++      
Sbjct: 1158 EKALP-EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216

Query: 851  KLVARVTRNPVP 862
            +  A V + P P
Sbjct: 1217 ESDATVKKKPAP 1228



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 66/246 (26%), Positives = 102/246 (41%), Gaps = 43/246 (17%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI--------- 680
            +G  P F +K +  +V EG  +LL+C++ + P   I W   G+ +   + I         
Sbjct: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153

Query: 681  SVAIES----DMHMY------------CSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
            SV+IE     D  +Y            CS     +     E T      +R  ++SLP V
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213

Query: 725  L--------KIKTGEKEPP------QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            L        K K   K PP      Q+I+  +   VR GESV L  +V G    T TW K
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273

Query: 771  NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
              K ++    +  ++  +   +TIL  ++ +  G YTL  EN  G  +    +TV +  +
Sbjct: 1274 FRKQIQESEHMKVENSENGSKLTILAARQ-EHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332

Query: 828  ENAEPP 833
              A  P
Sbjct: 1333 PPAGTP 1338



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           PP+    L  ++V++G+    S ++ G P+P +TW K N P++     S  + + + +L+
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219

Query: 794 PKKVK--DEGVYTLKAENSEGIAETSAVITVE 823
              V   D GVYT    N  G A  SA ++++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 7/152 (4%)

Query: 452 NQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAP 510
           ++D+ + Q+  T+   W+   +  D   YT        E +   +   ++P    Q   P
Sbjct: 666 SEDFHFEQRG-TQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ---P 721

Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLV 569
            F+ K R      G +V   C + G P P + W R   A+ K +  F++  ++D V TLV
Sbjct: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLV 780

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           +++V P  AG +  + KN  G  S    L+++
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 1/102 (0%)

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
            E+ +E     P F  + Q++ V E   + L  +V+ +P  +I W  N + +  ++ I  +
Sbjct: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1147

Query: 883  FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             +G    + I     E D G YKCVA N AG++    +VT+D
Sbjct: 1148 QEGSLCSVSIEKALPE-DRGLYKCVAKNDAGQAECSCQVTVD 1188



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 6/129 (4%)

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
            T P F +KLQD  V E    +L+ +++S+  A ++W  +G+ +K  K      + G +  
Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEGSLCS 1154

Query: 1074 LYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
            + I      D G Y C+ ++++    C+ +VTV + P    T+    K  +   +   + 
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214

Query: 1130 LTKGDALVR 1138
             T+ DA V+
Sbjct: 1215 GTESDATVK 1223



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 68/322 (21%), Positives = 122/322 (37%), Gaps = 29/322 (9%)

Query: 1226 DVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LK 1280
            +V W+ + + +   E    +  D     L + K    D   Y+C   +A+        L+
Sbjct: 444  EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQ 503

Query: 1281 VE---VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            VE   V+E  P      ++  +  G D  L    +  P P   W++N + I   ++ + +
Sbjct: 504  VERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARST 560

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS- 1396
             ++  A L I+     D G Y    EN  G       VT+ +K S      +L +  S  
Sbjct: 561  CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620

Query: 1397 ---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
               I +         + + +   V+       E I + N  + Q S ++          +
Sbjct: 621  TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES-EDFHFEQRGTQHS 679

Query: 1454 YAVNEVDISD-ASETTEYYKVIKETKIQSP-TVEKP-----------LKNITTEPNEDIE 1500
              + EV   D  + T E +    E + Q+  TV++P            +++T    + + 
Sbjct: 680  LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739

Query: 1501 LTCIFGGVPQPKVTWYRDGKKL 1522
            ++C   G P P V W RDGK L
Sbjct: 740  ISCAIAGDPFPTVHWLRDGKAL 761



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            + P FSK  +   V EGS    +C++   P+P++ W FK ++ +  E+    I+ D    
Sbjct: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 1864

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
            CS++ I++V    +  YT  AVN  GEA+    L ++T E+
Sbjct: 1865 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 4/135 (2%)

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            +NLK+ S    +    N+V+       T   +   E++  +P  ++ L+++     + + 
Sbjct: 1057 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDH 1556
            L C     P   + W  +GK LKT K    ++                   YKC+A ND 
Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176

Query: 1557 GEVETSCVVGIQQKP 1571
            G+ E SC V +   P
Sbjct: 1177 GQAECSCQVTVDDAP 1191



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 26/94 (27%), Positives = 42/94 (44%)

Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
           E P FI   + + +KE  T K   RV   P P +TW+RN + I+       +        
Sbjct: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           ++ +   E D G Y C A+N +G       +T++
Sbjct: 91  LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 2/121 (1%)

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            L AE  E   + S         E+    P F    +++ V E    +   ++   P P +
Sbjct: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840

Query: 865  TWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             W+++++ I  S     ++D + N  L+I++V  + D   Y C A NS G+++  A + +
Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELIV 1899

Query: 924  D 924
            +
Sbjct: 1900 E 1900



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            E PP+  T+L    V +G    F  ++T +    V W K    +Q S  + ++     Q 
Sbjct: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            L+I+  + DD G Y+C V N    A ++ E
Sbjct: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 4/101 (3%)

Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
            S+  S S+TL W     +GGS + +Y IE      K+W ++ T   +     ++++    
Sbjct: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDH 1398

Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
            E  FR+ A N  G S P  SQ   L      P  P   +E+
Sbjct: 1399 EYKFRVRAINVYGTSEP--SQESELTTVGEKPEEPKDEVEV 1437



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/88 (26%), Positives = 40/88 (45%)

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
            ++  +  G  + L     + P     W +N K +K  K    S +    S++I+K    D
Sbjct: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPS 1382
             G+YK   +N+ G A+    VT+ D P+
Sbjct: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA 1192



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164
            P     +++ +V +G+ A F+ ++    D  V WFKD   I+ S H Q+  D      L 
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
            I D   DD  +Y+C+    +G + CTA L VE
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 4/100 (4%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P P+V W++NG  + +   + +    + T  + I  +      KYT EA+N +G  
Sbjct: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115

Query: 1655 SVEVTLKVYDKPSKPEG-PVIMREI-SRESVT-IEWKPPL 1691
             V V L V    +K  G PV+ + +  R S + +E +P +
Sbjct: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSI 155



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTS 1654
            IEG P PEV+W+K+   +   + + I   E  +  + I ++     +KYT +A N+ G +
Sbjct: 1832 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1891

Query: 1655 SVEVTLKV 1662
            +    L V
Sbjct: 1892 TCTAELIV 1899



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
            P   + ++ + V +G +     ++ G P P + W K+++ ++         D D +   I
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            +      D+  YT KA NS G A  +A + VE   E   E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/103 (22%), Positives = 48/103 (46%), Gaps = 5/103 (4%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P    +LQ+  V +G K   + +++    A + W  +G  ++ +  I L+ +G    + I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157

Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204
                 +D G Y C    + G ++C+  +TV++   +   + PE
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200


>UniRef50_UPI0000F201CC Cluster: PREDICTED: similar to Myomesin 2;
            n=1; Danio rerio|Rep: PREDICTED: similar to Myomesin 2 -
            Danio rerio
          Length = 1097

 Score =  135 bits (326), Expect = 1e-29
 Identities = 121/496 (24%), Positives = 204/496 (41%), Gaps = 48/496 (9%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            +V WY++G  +       + T  +++ + +K + + H   YT+      GT  VE +  V
Sbjct: 213  DVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGT--VEHSAYV 270

Query: 1663 YDKPSK------PEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            Y K         P  P+ ++  +++R+ V + W PP  DG   +  Y IE+ +    +W 
Sbjct: 271  YVKDGSAVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWE 330

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQN------------PVGFSEALE-SEPIVIK 1761
            +  DV + V  Y +  L EN  Y FRV A N            P+  S+ LE S  +V+K
Sbjct: 331  RCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVK 390

Query: 1762 TA---------------LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
                             + VP            D  +V + W   +  G  P+  Y VE 
Sbjct: 391  VERGRQIVITKDQLEGQIRVPFPPTEVQVCELSDTYAV-LRWTEPDPRGREPL-KYFVER 448

Query: 1807 KQEG-KKWKXXXXXXXXXA-RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
               G + W          + R          +Y +R+ + N+ G S P      I++G+ 
Sbjct: 449  SISGTESWHLASMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQP 508

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
               P+ P   +    T+ SV L+W EP    G  I  Y +         W  I     + 
Sbjct: 509  QGVPAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITT 566

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSN 1981
                ++ +K   + +FR+ +    G S+ +E S  +R++    VPS P+A   +    + 
Sbjct: 567  TRFTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRVKAALNVPSCPSAISVLNCSRAE 626

Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
            +V+  W  P   GG P+ GY +  R  ++++W EV    V    + +  L E H    R+
Sbjct: 627  MVI-GWRAPVNHGGDPVRGYYLDQRQKSESIWREVNVRPVKERVYKLTGLQEGHFCQFRV 685

Query: 2042 YARNEIGLSEPLESDE 2057
            +A N IG+ +P E  E
Sbjct: 686  FAANIIGVGKPSEPSE 701



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 73/306 (23%), Positives = 120/306 (39%), Gaps = 11/306 (3%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P   V + E+S     + W  P D  G E  KY +E+       W  +A +D  V +   
Sbjct: 413  PPTEVQVCELSDTYAVLRWTEP-DPRGREPLKYFVERSISGTESW-HLASMDMTVLSTRF 470

Query: 1729 QKLNENC--EYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
               ++     Y +RV + N  G SE +L S+PI +     VP+            N SV 
Sbjct: 471  SAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQPQGVPAPPSGVLPMRDT-NSSVL 529

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYAR 1842
            + W       G  I+ Y +   + G  +WK          R  +  L  N  Y FR+ + 
Sbjct: 530  LQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRFTVDGLKSNKQYVFRVKSV 587

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
               G S+       I +   L  PS P    V   +   + + W  P ++GG P+  Y +
Sbjct: 588  GVSGNSIYSEESPVIRVKAALNVPSCPSAISVLNCSRAEMVIGWRAPVNHGGDPVRGYYL 647

Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            + +      W ++         + +  ++E     FR+ A N +GV  P+E   + L + 
Sbjct: 648  DQRQKSESIWREVNVRPVKERVYKLTGLQEGHFCQFRVFAANIIGVGKPSEPSELLLCEP 707

Query: 1963 ATVPSP 1968
             T+P P
Sbjct: 708  WTMPEP 713



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 20/227 (8%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVAT 567
           AP F   LRP     G  V+  C V+G+P P ITWF+  A ++P   +         +  
Sbjct: 64  APDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLHI 123

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX-XXXXXXXA 626
           L IR    EDAG +  +A+++ G A+S+  LIV    S  G+E  +             A
Sbjct: 124 LEIRRCSAEDAGEYKVIARSSLGEAASSATLIVN---SHEGAEAKLQRSFTPIPVPEPDA 180

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVA--IP-EPDIAWLFKGEEIVPDENISVA 683
            +    P TF        V EG +++L+C      +P + D+ W   G  + P    S  
Sbjct: 181 QLASTFPSTF--------VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRP----SSR 228

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730
           +E    +  + L + +V K  EG YTV     +G       + +K G
Sbjct: 229 VELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGTVEHSAYVYVKDG 275



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 27/83 (32%), Positives = 44/83 (53%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T  ++G P PE+ W KN  ++ +  +YNI  + K+S + I  +    S  Y+I   N  
Sbjct: 1013 LTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSMEDSGNYSIFVRNKH 1072

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVI 1674
            G+ +V VT+ VY    KP G  +
Sbjct: 1073 GSQTVLVTVSVYKHGEKPRGDAV 1095



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDE---WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +K G ++ L   +     P  +   W  +   ++     +     +SASLT+K V     
Sbjct: 191  VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHE 250

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSIN-----ICWDEPEN 1406
            G+Y +RL    G  +    V + D  +     PG P  L++  S +N     + W  P  
Sbjct: 251  GLYTVRLRTWDGTVEHSAYVYVKDGSAVVVGAPGSP--LQVKCSDVNRDYVFLSWIPPSA 308

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             G + +  Y +E  +I   +W    ++ +   Q  +  LK N+ Y+FR  AVN+  +   
Sbjct: 309  DGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRP 368

Query: 1465 SETTE 1469
            S+ +E
Sbjct: 369  SKPSE 373



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1963 ATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
            A V   P +PL+++   V  + V  SW  P  DG A + GY I   D+    W     V 
Sbjct: 277  AVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVI 336

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                ++ +  L EN  Y  R+ A N+ G+  P +  EP
Sbjct: 337  QKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEP 374



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 25/213 (11%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P FS   +   V  G D+ L C +   P+P I W      + P    +  I S   ++  
Sbjct: 65  PDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLH-- 122

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---------------KEPP-QV 737
           +L+I        G Y V+A +  GEA+    L + + E                EP  Q+
Sbjct: 123 ILEIRRCSAEDAGEYKVIARSSLGEAASSATLIVNSHEGAEAKLQRSFTPIPVPEPDAQL 182

Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRP---TITWCKNN---KPVKALPTKSDGDTHSITI 791
                S  V++G++++L         P    +TW ++    +P   +  ++   + S+T+
Sbjct: 183 ASTFPSTFVKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTV 242

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
               K + EG+YT++    +G  E SA + V++
Sbjct: 243 KHVHK-EHEGLYTVRLRTWDGTVEHSAYVYVKD 274



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 25/211 (11%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSD-GDTHSITIL 792
           P    PL+   V  G  V LS  V G P P+ITW K++ P++  LP          + IL
Sbjct: 65  PDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLHIL 124

Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL---------------F 835
           + ++   +D G Y + A +S G A +SA + V   + E AE  L                
Sbjct: 125 EIRRCSAEDAGEYKVIARSSLGEAASSATLIVN--SHEGAEAKLQRSFTPIPVPEPDAQL 182

Query: 836 INRFQEITVKEKGTIKLVARVTRNPVP---SITWYRNNEIISPSETITQNFDGENIELVI 892
            + F    VKE   + L    T   +P    +TWYR+   + PS  +       +  L +
Sbjct: 183 ASTFPSTFVKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTV 242

Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +V  E   G Y        G   H A V +
Sbjct: 243 KHVHKE-HEGLYTVRLRTWDGTVEHSAYVYV 272



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            P+PP     +   +SS+ + W EP  T    I+ Y +   E  + +W ++ N  IT T+ 
Sbjct: 512  PAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRF 569

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            ++  LK+N  Y FR  +V     S  SE +   +V
Sbjct: 570  TVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRV 604



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 14/53 (26%), Positives = 30/53 (56%)

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            +  ++ K +++  +++P    PL+  T     D++L+C   G P P +TW++D
Sbjct: 49   KAAQHLKHVQDLSLKAPDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKD 101



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 21/94 (22%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435
            L+ PS P   ++L    + + I W  P N G   +  Y ++ ++   + W  ++V+ + +
Sbjct: 608  LNVPSCPSAISVLNCSRAEMVIGWRAPVNHGGDPVRGYYLDQRQKSESIWREVNVRPVKE 667

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                +  L+     +FR +A N + +   SE +E
Sbjct: 668  RVYKLTGLQEGHFCQFRVFAANIIGVGKPSEPSE 701



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 850 IKLVARVTRNPVPSITWYRNNEIISP----SETITQNFDGENIELVITNVDSEIDSGDYK 905
           +KL   V   P PSITW++++  + P    +  I+  F G +I L I    +E D+G+YK
Sbjct: 82  VKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRF-GLHI-LEIRRCSAE-DAGEYK 138

Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
            +A +S G+++  A + ++  +    K LQ+S+
Sbjct: 139 VIARSSLGEAASSATLIVNSHEGAEAK-LQRSF 170



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNIT--KTQ 1437
            P PP +  + E+  +   + W EP+  G   + Y+ VE     T  W ++  ++T   T+
Sbjct: 411  PFPPTEVQVCELSDTYAVLRWTEPDPRGREPLKYF-VERSISGTESWHLASMDMTVLSTR 469

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             S  + +   SY +R  +VN+  IS+ S
Sbjct: 470  FSAFDQQKGKSYSYRVRSVNKYGISEPS 497



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/107 (21%), Positives = 54/107 (50%), Gaps = 5/107 (4%)

Query: 726  KIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TK 781
            +++  EK   +V + L  ++ + + +S+ L+  V G+P P + W KN++ + +      K
Sbjct: 984  QVEFAEKNRARVTKGLPDVVAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIK 1043

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            ++  + ++TI     ++D G Y++   N  G       ++V +  E+
Sbjct: 1044 NENKSSTLTI-NHVSMEDSGNYSIFVRNKHGSQTVLVTVSVYKHGEK 1089



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            + + E  ++ L   V  +P P + W +N+  IS +       + ++  L I +V  E DS
Sbjct: 1003 VAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSME-DS 1061

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEK 927
            G+Y     N  G  S    VT+ V K
Sbjct: 1062 GNYSIFVRNKHG--SQTVLVTVSVYK 1085


>UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndrome
            cell adhesion molecule, partial; n=2; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to Down syndrome cell
            adhesion molecule, partial - Strongylocentrotus
            purpuratus
          Length = 2430

 Score =  135 bits (326), Expect = 1e-29
 Identities = 180/820 (21%), Positives = 308/820 (37%), Gaps = 75/820 (9%)

Query: 695  LKITNVKKFQEGTYTVVAVNR---EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            L I +V+    G Y     NR     + S P VL +       P++I+      +R GE+
Sbjct: 624  LHIRDVRDRDAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGET 683

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            V L     G P PT  W K+  PV   P  S        +L   ++++ G Y  +A N  
Sbjct: 684  VELPCVASGYPLPTYQWTKDGVPVT--PGDSRSLRGGNLLLSNVQLENAGRYDCEAVNDL 741

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G   T+  + V +       P       Q+ +V           V+  P+  +TWY+N +
Sbjct: 742  GAVSTTRNVIVRDSIAVYFYP-------QKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQ 794

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
             +   + +T     EN  +V+  +  + D G Y+CVASNS        ++++   K   +
Sbjct: 795  PLDGDDRVTVY---ENGTMVVGGMRRD-DRGMYQCVASNSWQTQEATMQLSLGAAKPIML 850

Query: 932  KHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISG---MDHREIIQEGRXXXXXX 986
             H       + G  + L C  +   T    W  +   I         ++I E        
Sbjct: 851  AHFTNQ-TLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYL 909

Query: 987  XXXX--XXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEIN 1041
                    D G+ +C    +  +     +  +     +R L D   +   DV+I    + 
Sbjct: 910  NISRLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSIHCHVVG 969

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCT 1097
                 + W + G    P   +++    G +  +    TS  D GEY+C+      D S +
Sbjct: 970  FPITSITWYK-GLTTLPSSMRHNVFPNGTL--VIADVTSYGDGGEYTCVASNARGDRSAS 1026

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLT 1155
                +V++PP +I  ++   + +G +      +T+GD  +  RW KDG  I     I+  
Sbjct: 1027 DMDLIVKVPP-VIQPIEPLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHGVGIEFV 1085

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKC----TAILTVEEPSINFTLRLPEFILVPAN 1211
                   L I D      G Y+CE  N       T  LT++ P        P F++ P N
Sbjct: 1086 NGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVP--------PRFVVEPHN 1137

Query: 1212 TDAYL--TVEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVK-----KRTLIIRKCT 1259
            T   L  TV I          DV W K    I  T    L  D +       +L+IR+  
Sbjct: 1138 TAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREAR 1197

Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPN 1318
             +D   Y C + ++         +  F P   + +++   ++    +TL           
Sbjct: 1198 VEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELTESITLECIATGHQPLE 1257

Query: 1319 DEWIVNSKIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
              W  N     +    +  I      DS  +S+TI      D   Y    +N  G  +  
Sbjct: 1258 IMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQNLHGADEHV 1317

Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-- 1430
            + + + +KP PP   +++   S  + + W +P   GNS +  + +EY+         +  
Sbjct: 1318 IQLWVQEKPEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQTGLPQ 1376

Query: 1431 ----KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
                 ++   Q SI++L    +Y  R +A N + ISD S+
Sbjct: 1377 EHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSK 1416



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 202/996 (20%), Positives = 370/996 (37%), Gaps = 102/996 (10%)

Query: 1073 KLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVVE---LPPEIITRLQNQKVNKGN 1122
            +L+IR+    D G+Y C +R+        S  A + V E     PE+I    +  +  G 
Sbjct: 623  ELHIRDVRDRDAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGE 682

Query: 1123 KATFEIE-LTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
              T E+  +  G  L   +W KDG  +   +   L    +   L + +  L++AG Y CE
Sbjct: 683  --TVELPCVASGYPLPTYQWTKDGVPVTPGDSRSL----RGGNLLLSNVQLENAGRYDCE 736

Query: 1180 VGNSKCTAILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLD-VTWYKKKSV 1235
              N    A+ T     +  ++ +   P+   V     A     +    ++ VTWYK    
Sbjct: 737  AVND-LGAVSTTRNVIVRDSIAVYFYPQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQP 795

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDY 1293
            ++  ++ T+  +    T+++     DD+  Y CV  ++  T +  +++ +    P ++ +
Sbjct: 796  LDGDDRVTVYEN---GTMVVGGMRRDDRGMYQCVASNSWQTQEATMQLSLGAAKPIMLAH 852

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI---DSKSAS-LTIK 1348
                 ++ G ++ L       P P+  W+ +   I    ++T   +   DS   S L I 
Sbjct: 853  FTNQTLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNIS 912

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG 1408
            ++ + D G+Y+    +  G    E  + ++ +P     P+++ ID + ++I        G
Sbjct: 913  RLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSI---HCHVVG 969

Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN--SSYRFRAYAVNEVDISDASE 1466
                I  +  Y+ + T       N+    T +    T+      +   A N      AS+
Sbjct: 970  FP--ITSITWYKGLTTLPSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASD 1027

Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525
                 KV        P V +P++ +T    +  +L CI      P    W +DG+ +   
Sbjct: 1028 MDLIVKV--------PPVIQPIEPLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHG 1079

Query: 1526 KA-TYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNED 1579
                + N                   Y C A N    V  +  + IQ  P  V+   N  
Sbjct: 1080 VGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTA 1139

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYK--------NGNKLENDKEYNITTKEKTSVIR 1631
            +   H V    ++  +  G P P+V W K        N   L +D  + +  +E  S++ 
Sbjct: 1140 VVLNHTV----VIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEM--QENGSLV- 1192

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE----W 1687
            I+E +   +  Y    SN+ G  S   TL V+   +  +    +     ES+T+E     
Sbjct: 1193 IREARVEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELTESITLECIATG 1252

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
              PL+   +  +K  +  +     R+    V D D  + +  I     +    +  +AQN
Sbjct: 1253 HQPLE---IMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQN 1309

Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
              G  E +    + ++   + P+            +  V ++W PS  +G SP+  + +E
Sbjct: 1310 LHGADEHVIQ--LWVQEKPEPPTDLHVVNKT----SRGVLLSWQPS-FDGNSPVTGFTLE 1362

Query: 1806 IKQEGKKWKXXXXXXXXXA-------RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             K     W+         A        I+ L    TY  RI+A N IG S P       T
Sbjct: 1363 YKNASDAWQTGLPQEHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDT 1422

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII-----EFKTVKGKSWT 1913
              +       P+  V ++      ++K   P       I  +         K +   +  
Sbjct: 1423 EEEDAWQTGLPQEHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDTEE 1482

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973
            ++      +    + N+K+      ++ A N V V   +  Q V   +   VPS     +
Sbjct: 1483 EVPVETNYIESRTLTNLKKFTRYTIQLRAYNRVNVGPWSPQQFVTTLE--DVPSEAPHDV 1540

Query: 1974 EIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV 2008
              R VGS  +M  W  P+       L GY +  R +
Sbjct: 1541 SARSVGSTSIMVFWNAPDQVSLNGILQGYRVYYRPI 1576



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 122/577 (21%), Positives = 213/577 (36%), Gaps = 63/577 (10%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+ + VD G+     C +   P   + W    + +  D+ ++V     M        +  
Sbjct: 762  PQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYENGTM-------VVGG 814

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            +++   G Y  VA N        + L +   +   P ++    +  ++ G ++ LS  V 
Sbjct: 815  MRRDDRGMYQCVASNSWQTQEATMQLSLGAAK---PIMLAHFTNQTLQPGPNLQLSCTVA 871

Query: 760  GNPRPTITWCKNNKPVKALP-------TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            GNP P +TW ++  P+   P          D D  S   +     +D G+Y  +A     
Sbjct: 872  GNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEA----- 926

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
               TS +  V+     N      +    ++   +   + +   V   P+ SITWY+    
Sbjct: 927  ---TSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSIHCHVVGFPITSITWYKGLTT 983

Query: 873  ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            + PS      F   N  LVI +V S  D G+Y CVASN+ G  S  + + + V+    ++
Sbjct: 984  L-PSSMRHNVF--PNGTLVIADVTSYGDGGEYTCVASNARGDRS-ASDMDLIVKVPPVIQ 1039

Query: 933  HLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
             ++      +G+   L C   +  + +  +W  + + I      E +             
Sbjct: 1040 PIE-PLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADA 1098

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TA 1045
                 G   C   +   +       TI   P F+ +  +  V      ++    N +   
Sbjct: 1099 STVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPNP 1158

Query: 1046 DVVWER-DGEIIK------PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094
            DV W++  G I        P   +++ ++ G    L IR   V D G Y C + +    E
Sbjct: 1159 DVQWKKAPGPITTTNFRDLPDDPRFEMQENG---SLVIREARVEDAGYYLCHISNSVGME 1215

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN--- 1150
            S TA +TV  +P     + QN  V      T E   T    L + W K  +++ F+    
Sbjct: 1216 SKTATLTVF-VPATFEQQQQNVTVELTESITLECIATGHQPLEIMWSK--NDVPFNRLTT 1272

Query: 1151 ---HIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGN 1182
                I+   DG      + I+    DD   Y C   N
Sbjct: 1273 ARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQN 1309



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 50/190 (26%), Positives = 91/190 (47%), Gaps = 8/190 (4%)

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFR 1838
            N ++ + W  S  NGGS I+ +++  ++  ++ W+         + R   L   T Y+F 
Sbjct: 1849 NNAIKVNW-RSTGNGGSSIVAFQLLYQRTHEQTWERFDVNASLRSFRATDLLCGTGYRFY 1907

Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            I ARN++G   P       T G+   PPS  +  +V  + + S+TL     +S GG PI 
Sbjct: 1908 ITARNKLGVGKPSDILSVSTQGEIPIPPSTDK--IVPFTNASSITLVLASWQS-GGCPIE 1964

Query: 1899 NYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL-PTESQS 1956
            +Y I+++ +    W  I   + G+  ++ +++++      FR++A NT G S+ P    +
Sbjct: 1965 SYSIQYQVLGVDDWENIANNLPGNTRDYTVDDLRPLTWYQFRVTAVNTAGPSVYPFRVST 2024

Query: 1957 VRLEKHATVP 1966
            V      T P
Sbjct: 2025 VAFSGSGTAP 2034



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 85/394 (21%), Positives = 151/394 (38%), Gaps = 34/394 (8%)

Query: 1669 PEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDRDVET 1725
            PE P  ++    S  S+ + W PPL   G+ +T Y +  ++    N   +  ++D     
Sbjct: 1645 PEAPADIKAHAASPTSIMVSWLPPLYLNGI-ITHYHLNIQYREGENEVRQEKELDPTTYY 1703

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXID-NES 1783
            Y ++ L  + EY F V A    G  E   S  I  +  +  VP+                
Sbjct: 1704 YLVEDLQTDYEYDFWVKASTIAGQGE---SSRIATEIPMSRVPARIMSFSTTLMTPWKRG 1760

Query: 1784 VYITWFPSEKNGGSPIIDY---KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
            V +   P     G P++     K  +    K              IQ +       +   
Sbjct: 1761 VTLDCLPV----GDPVLTVEWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCR 1816

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A NE G+S      D IT+   +  P  P    +  +++ ++ + W     NGGS I  +
Sbjct: 1817 AINEYGSS------DSITVRVQVLAPPNPPQLTIGSTSNNAIKVNW-RSTGNGGSSIVAF 1869

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             + ++    ++W +   V  S+      ++       F I+A N +GV  P++  SV  +
Sbjct: 1870 QLLYQRTHEQTWERF-DVNASLRSFRATDLLCGTGYRFYITARNKLGVGKPSDILSVSTQ 1928

Query: 1961 KHATVPSPPTAPLEIRMVGSN---IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV- 2016
                +P PP+    +    ++   +V+ SW +    GG P+  Y+I  + +    W  + 
Sbjct: 1929 --GEIPIPPSTDKIVPFTNASSITLVLASWQS----GGCPIESYSIQYQVLGVDDWENIA 1982

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
              +  NT  + + DL     Y  R+ A N  G S
Sbjct: 1983 NNLPGNTRDYTVDDLRPLTWYQFRVTAVNTAGPS 2016



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP-EDAGTF 581
            DG+ V   C V G+P   ITW++    +  S    ++ +     TLVI +V    D G +
Sbjct: 957  DGTDVSIHCHVVGFPITSITWYKGLTTLPSSMRHNVFPN----GTLVIADVTSYGDGGEY 1012

Query: 582  TCVAKNAAGFAS-STTELIVEAP 603
            TCVA NA G  S S  +LIV+ P
Sbjct: 1013 TCVASNARGDRSASDMDLIVKVP 1035



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 8/92 (8%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM-----EVGKVD 2020
            P PPT  L +    S  V+ SW  P +DG +P+ G+ +  ++ +   W      E    D
Sbjct: 1326 PEPPT-DLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDA-WQTGLPQEHVPAD 1382

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            +   +++I+ L   +TY +RI+A N IG+S+P
Sbjct: 1383 LIGYQYSIKHLHPAYTYHVRIFAFNAIGISDP 1414



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 14/215 (6%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI----VTVGGS 1921
            P  P +  V   TSR V L W +P  +G SP+T + +E+K       T +    V     
Sbjct: 1326 PEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQTGLPQEHVPADLI 1384

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH-ATVPSPPTAPLEIRMVGS 1980
             +++ I+++        RI A N +G+S P++      E+  A     P   +   ++G 
Sbjct: 1385 GYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDTEEEDAWQTGLPQEHVPADLIGY 1444

Query: 1981 NIVMTSWGTPEWDGGAPLLGYN-IAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSE----- 2033
               +     P +     +  +N I I D +K +  +   +V V T     R L+      
Sbjct: 1445 QYSIKHL-HPAYTYHVRIFAFNAIGISDPSKEILFDTEEEVPVETNYIESRTLTNLKKFT 1503

Query: 2034 NHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSH 2068
             +T  +R Y R  +G   P +     + +P E  H
Sbjct: 1504 RYTIQLRAYNRVNVGPWSPQQFVTTLEDVPSEAPH 1538



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-----ATLVIREVFPEDAGT 580
            TV   C   G P P + W +    I  + +F+   DD         +LVIRE   EDAG 
Sbjct: 1145 TVVIACMANGKPNPDVQWKKAPGPITTT-NFRDLPDDPRFEMQENGSLVIREARVEDAGY 1203

Query: 581  FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            + C   N+ G  S T  L V  P +    +  V
Sbjct: 1204 YLCHISNSVGMESKTATLTVFVPATFEQQQQNV 1236



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 5/125 (4%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           D   Y   ++ +L       P      +E  + AP  ++         G TV+  C   G
Sbjct: 633 DAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGETVELPCVASG 692

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
           YP P   W +    + P     +         L++  V  E+AG + C A N  G  S+T
Sbjct: 693 YPLPTYQWTKDGVPVTPGDSRSL-----RGGNLLLSNVQLENAGRYDCEAVNDLGAVSTT 747

Query: 596 TELIV 600
             +IV
Sbjct: 748 RNVIV 752



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+   F C V GYP  Q+TW++    +       +Y +     T+V+  +  +D G + C
Sbjct: 770 GAFATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYEN----GTMVVGGMRRDDRGMYQC 825

Query: 584 VAKNAAGFASSTTELIVEA 602
           VA N+     +T +L + A
Sbjct: 826 VASNSWQTQEATMQLSLGA 844



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 4/85 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII--KPSQDFQ--MYYDDDNV 565
           PI +     +    G  +Q  C V G P P +TW R    I   P   F   +  D D +
Sbjct: 847 PIMLAHFTNQTLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVI 906

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAG 590
           + L I  +  ED G + C A +  G
Sbjct: 907 SYLNISRLVSEDGGLYRCEATSELG 931



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 51/243 (20%), Positives = 81/243 (33%), Gaps = 15/243 (6%)

Query: 595  TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
            ++ L++    + H    T               +   +PP F  +P    V     +++ 
Sbjct: 1090 SSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIA 1149

Query: 655  CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY-CSVLKITNVKKFQEGTYTVVAV 713
            C     P PD+ W      I       +  +    M     L I   +    G Y     
Sbjct: 1150 CMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREARVEDAGYYLCHIS 1209

Query: 714  NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
            N  G  S    L +      P    +  +++ V   ES+ L     G+    I W KN+ 
Sbjct: 1210 NSVGMESKTATLTVFV----PATFEQQQQNVTVELTESITLECIATGHQPLEIMWSKNDV 1265

Query: 774  PVKALPTK-------SDGDT--HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            P   L T        +DGD+   S+TI    +  D   Y   A+N  G  E    + V+E
Sbjct: 1266 PFNRLTTARYDIETVTDGDSVLSSMTIFSAVR-DDTATYICLAQNLHGADEHVIQLWVQE 1324

Query: 825  PTE 827
              E
Sbjct: 1325 KPE 1327


>UniRef50_A7DN46 Cluster: Fibronectin, type III domain protein
            precursor; n=1; Candidatus Nitrosopumilus maritimus
            SCM1|Rep: Fibronectin, type III domain protein precursor
            - Candidatus Nitrosopumilus maritimus SCM1
          Length = 9645

 Score =  134 bits (324), Expect = 3e-29
 Identities = 118/439 (26%), Positives = 182/439 (41%), Gaps = 29/439 (6%)

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVIMREISRESV 1683
            + ++ + + +L       + + A N  G S     + K    P  P+   +  + + + V
Sbjct: 6600 DTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDPATASAKPATTPGAPDA--LQLDFANQLV 6657

Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD--VDRDVETYCIQKLNENCEYMFRV 1741
            ++EW  P DDGG E+  Y +E +  D + WI   D     +     +  L    +Y FR+
Sbjct: 6658 SLEWAVPTDDGGDEIDDYIVE-YSLDTSEWIVFPDNVTPANSTAVTVTDLINGFQYFFRI 6716

Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801
               N  G  E  E       T    P            DN SV++TW   E  GG+P+  
Sbjct: 6717 SGVNIAGIGEPSEFRATTPATLPSAPRDLEATR-----DNTSVHLTWNVPEDLGGAPLSA 6771

Query: 1802 YKVEIKQEGK----KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
            Y VE    G+    K+            +  L+    YQFRI A+N   T     SD   
Sbjct: 6772 YMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQYQFRITAKNTAITDFGPASD--- 6828

Query: 1858 TIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            T+  T  T P+ PR+ VV    +++ TL W  PESNGG  IT+Y IE + + G+ W    
Sbjct: 6829 TVSATPATTPTAPRDLVVIAGNNQA-TLSWNVPESNGGDSITDYKIEIR-IAGQDWDVYD 6886

Query: 1917 T-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
              V  +     I N+       FR++A N+V    P  +  V   K AT+P+PP   + I
Sbjct: 6887 DGVSTTTQGIVIPNLTNGVTYEFRVTAINSVN---PGPASDVVPGKPATIPTPPKKLVVI 6943

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAI-RDVT-KTMWMEVGKVDVNTLKFNIRDLSE 2033
               G   +  +W  P  +GG+ +  Y +    D T       V   D+  L   I  L  
Sbjct: 6944 --PGDTKLDVTWTKPTNNGGSAITSYLVQYSTDGTFDASTPSVTVTDLTNLMVTISGLEN 7001

Query: 2034 NHTYMIRIYARNEIGLSEP 2052
            +    +++ A N +G S P
Sbjct: 7002 DVPIHVQVTAINGVGSSGP 7020



 Score =  131 bits (316), Expect = 2e-28
 Identities = 178/758 (23%), Positives = 292/758 (38%), Gaps = 66/758 (8%)

Query: 1346 TIKKVENTDAGI-YKLRL--ENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICW 1401
            T+  +E+ + G+ Y+ R+  EN  G  D    +T      P     +  +  +  +++ W
Sbjct: 4791 TVVDIEDLENGVEYQFRISAENEVGFGDPSAPITATPVDGPSQVTGLSGQRGNGEVSLSW 4850

Query: 1402 DEPENTGNSTIIYYVVEYQE--IDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNE 1458
             EP + G  TI  YV+EY +     T   +V  +   T   I NL+   +Y FR YA N+
Sbjct: 4851 SEPFD-GGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLENGVTYEFRVYAQND 4909

Query: 1459 VDISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            +D    S T         T   +  PT      ++    + D   + I   + + K+   
Sbjct: 4910 IDDGPVSTTISVTPATVPTPPTNLIPTFGSTQVSLGWTASSDDGGSDIDDYIVEFKLKSE 4969

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
             D +      +                    ++  A ND G  + S V   +  P    +
Sbjct: 4970 SDWQVFNDGVSDVPG---ATVTGLTNGQIYEFRVKAHNDVGNSDPSEVK--EATPAAPPA 5024

Query: 1577 NEDIKQKHKVGDEWLVT-----AVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVI 1630
              +I     VG +  VT     A   G P  E   + + +  END +  I    ++T  I
Sbjct: 5025 APEILTA--VGSDETVTVTWNLAATNGAPVTEYELHYSIDGFENDIDNIIVVATQETGPI 5082

Query: 1631 R--IKELKRSHSSKYTIEASNTAGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIE 1686
               +++L+ + +  + + A++ A       TL    +  P+ P      R      VT++
Sbjct: 5083 SYPVEDLENARTYSFKVRANSIASFGPFSNTLDAVPFTTPNAPTDLEATR--GNGEVTLQ 5140

Query: 1687 WKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            W  P  +GG  +T Y +E        +   +      D  T  I  L+    Y FRV A 
Sbjct: 5141 WNKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAV 5200

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
            N  G  E   S+ I   T   VP+            +ESV + W PSE  GG  +IDY +
Sbjct: 5201 NAAG--EGALSD-IATATPATVPAAPTLDTATPG--DESVLLGWTPSENTGGDALIDYLI 5255

Query: 1805 EIKQ------EGKKWKXXXXXXX-----XXARIQKLSINTTYQFRIYARNEI-GTSLPYT 1852
            + ++          W                 I  L+   TY+FR++A+N + G SLP  
Sbjct: 5256 QFRELDATNDAESNWTTFDEGNGGVNVLTSITIDDLTNGVTYEFRVFAKNTVPGQSLP-- 5313

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKGK 1910
                +   +  + PS PR+  V+      V++ W  P  NGG  I  Y +++        
Sbjct: 5314 --SNVLSAEPSSAPSVPRDLRVTNIGDEFVSISWLAPADNGGDDIVGYTVQYSDDNFTTI 5371

Query: 1911 SWTKIVTVGGSV-HEHCIENIKEKDEIIFRISAEN-TVGVSLPTES--QSVRLEKHATVP 1966
            S  +IV V G +  +  + +++   +  FR+ A N      +P  S           TVP
Sbjct: 5372 STQEIVPVSGVLPTDATVSSLENGVDYQFRVIAHNEDDDPQIPDSSDPSDPVTGTPGTVP 5431

Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-------AIRDVTKTMWMEVGKV 2019
              PT  +   + G+ I +  W  P  DGG  + GY I       A  +VT T        
Sbjct: 5432 GIPTDLVATTLSGTEIQLV-WQAPSDDGGRAVSGYLIERLGTDGAFAEVTTTTIPVPESP 5490

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              +   F    LS   TY  R+ A N +G  +P ++D+
Sbjct: 5491 TASDTTFTDTGLSLGTTYTYRVSAVNVLGTGDPSDTDD 5528



 Score =  129 bits (311), Expect = 9e-28
 Identities = 126/487 (25%), Positives = 205/487 (42%), Gaps = 36/487 (7%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            E+ +  +G   +N     ++     +   +  L    +  + + A N  G SS    L  
Sbjct: 1502 EIQYSTDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENG-SSPPSNLDT 1560

Query: 1663 YDKPSKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
                + P+ PVI         E VTI W  P + GG  +T Y I+  +P    W  V+  
Sbjct: 1561 ATPATIPDAPVIDPAQTVTGNEFVTIAWSTPYN-GGSPITHYVIQV-KPAGGSWETVSSN 1618

Query: 1720 DRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778
              D +    IQ L    E+ FRV A N  G ++   S  I + T  DVP+          
Sbjct: 1619 FNDPQNILTIQNLENGVEHSFRVAAVN--GVNQGPYSA-IELATPGDVPAQILDLSVERG 1675

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKK---WKXXXXXXXXXARIQKLSINTT 1834
              +E V +TW  +  N G PI DY +E+   +G     +            +  L     
Sbjct: 1676 --DEQVLLTW-SAPNNHGFPITDYVIEVDYGDGNGFVVYNDGQSIDTTDVPVTGLENGVL 1732

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS--VTLKWTEPESN 1892
            ++FR+YA N +G + P    +        TP   P   V++E  +    + + W+ P+ +
Sbjct: 1733 HKFRVYAVNALGNATPSNEVEA-------TPARAPDAPVITELNAGDGQIEVIWSTPD-D 1784

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSL 1950
            GG  I  Y +E+ T    S    VT+ G+  +  + +  +   D   FR+ A N V  S 
Sbjct: 1785 GGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTYYFRVIAINDVDESD 1844

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
            P++ +S       TVP+ P   L   +VG + +  SW  P  DGG+PL GY ++I DVT 
Sbjct: 1845 PSDVESAI---PVTVPAKPV--LNTPVVGDSSLTVSWSAPN-DGGSPLTGYTLSITDVTG 1898

Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV-IPGEGSHA 2069
                    +  N + +N  +L+  +TY   + A N  G S+P ++     +  PG+    
Sbjct: 1899 GNTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDPSDAVTGIPIGAPGQIDDL 1958

Query: 2070 DEEPGEQ 2076
              E G++
Sbjct: 1959 GAESGDK 1965



 Score =  127 bits (307), Expect = 3e-27
 Identities = 119/487 (24%), Positives = 191/487 (39%), Gaps = 41/487 (8%)

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKE-----LKRSHSSKYTIEASNTAGTSSVE--VTLK 1661
            +G K+E   + N  T  +T+  +  +     L+   +  Y I A N  GT +     +  
Sbjct: 8310 SGYKIEQSTDNNTWTVLETTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASDVASAT 8369

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE-------LTKYAIEKHEPDNNRWI 1714
              D P  P    +        VT+ W  P  DGG+        +T Y +  +  D N W 
Sbjct: 8370 PLDVPGPPRN--LQTTPGNAQVTLAWDIPSTDGGITADNGGSIITGYVVH-YAIDTNFWK 8426

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
               +      T  +  L     Y FRV A N VGF   L    +  +  + VP       
Sbjct: 8427 TFNEEPITERTVDVTGLTNGQNYKFRVFAVNEVGF---LHPSLVSSEIPVTVPERPWGLT 8483

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-----WKXXXXXXXXXARI--- 1826
                  N+ + ++W     NGGS I  YK++ K  GK      W                
Sbjct: 8484 ITAPSQNQ-INLSWKTPLDNGGSTITGYKIQ-KTIGKPTTNSVWSDAPSGTLGTVNSWSD 8541

Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
              L   TTY +R+    +        S        TL+ P  PRN  + E+  + + + W
Sbjct: 8542 TNLIPGTTYSYRVITLTDAVPDGDSNSASGAIFATTLSVPGAPRNLTL-EAEGKKIVIDW 8600

Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAEN 1944
              P SNGG+PI NY+I++    G  W  +     +V    ++  NI    E   R+ AEN
Sbjct: 8601 VAPTSNGGTPIVNYLIQWSDNGGSKWNTLKRDASAVTSATVKSSNIVLGTEYQIRVYAEN 8660

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004
            T+G   P  + SV+     T+P+ P + +     G   V+ SW  P  DGG+ +  Y + 
Sbjct: 8661 TIG---PGPASSVKSVTPTTIPTAPRSLVTDPQDGQ--VVLSWSKPLSDGGSAITDYLVR 8715

Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064
              +     ++        +    +  L+ + TY  R+ A N +G + P  + +   V  G
Sbjct: 8716 YSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRVVAVNSVG-NSPASTGK--SVAVG 8772

Query: 2065 EGSHADE 2071
            EG+ ++E
Sbjct: 8773 EGNSSEE 8779



 Score =  124 bits (300), Expect = 2e-26
 Identities = 172/699 (24%), Positives = 270/699 (38%), Gaps = 67/699 (9%)

Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEY--QEIDTTEWISVKNI----TK 1435
            PGK  I+ +   ++ + + W EP N G + I  Y +EY   E D    +   ++    + 
Sbjct: 4435 PGKTEIISLTPGNAQVEVEWSEPTN-GGTPITGYRIEYTTNETDANNGVFTSSVDVAASP 4493

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDI---SDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
               +I NL    +Y FR  A N VD    SD    T        T + +   +  +    
Sbjct: 4494 LSATINNLNNGDTYYFRVTATNSVDFGEPSDVDSATPARAPDAPTDLVATLGDGQVTIGF 4553

Query: 1493 TEPNEDIELTCIFGGVPQPKVT---WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
            T P ED     I   +         W+    +  T   T E                 ++
Sbjct: 4554 TPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQ--TESTTPE----ITVTGLNNGQEYLFR 4607

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNE-DI---KQKHKVGDEWLVTAVIEGIPPPE-V 1604
             +A N  G  + S  V + + P     N  D+   +   +V   W   AV  G+P    +
Sbjct: 4608 AVAVNGVGPGDES--VPVAETPAALSGNPTDLVATRGNTQVSLTWAAPAVTGGVPVTSYI 4665

Query: 1605 IWYK---NGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            + Y    NG+   N     +T++     T+ I I  L+   +  + + A NTAG S    
Sbjct: 4666 VEYTDDANGDFGANPSSQTVTSETLPVPTNTI-INGLQNGVTYTFRVIAVNTAGPSGPSN 4724

Query: 1659 TLKVYDKPSK-PEGPVIMR-EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN--NRWI 1714
            T     KP+  P+ P     + S  +V + W P  + GG  + +Y I+    ++      
Sbjct: 4725 TDTA--KPATVPDAPTFDDPQPSAGTVGLSWTPG-NTGGEPIERYRIDYTSANSFVEGQY 4781

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            +   V        I+ L    EY FR+ A+N VGF +   S PI   T +D PS      
Sbjct: 4782 QSEFVTHPTTVVDIEDLENGVEYQFRISAENEVGFGD--PSAPIT-ATPVDGPSQVTGLS 4838

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX----XXXARIQKLS 1830
                  N  V ++W     +GG  I  Y +E  ++G                 A I  L 
Sbjct: 4839 GQR--GNGEVSLSW-SEPFDGGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLE 4895

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
               TY+FR+YA+N+I    P ++   +T     TPP+     ++    S  V+L WT   
Sbjct: 4896 NGVTYEFRVYAQNDIDDG-PVSTTISVTPATVPTPPTN----LIPTFGSTQVSLGWTASS 4950

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
             +GGS I +YI+EFK      W         V    +  +       FR+ A N VG S 
Sbjct: 4951 DDGGSDIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVGNSD 5010

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL----LGYNIAIR 2006
            P+E       K AT  +PP AP  +  VGS+  +T         GAP+    L Y+I   
Sbjct: 5011 PSE------VKEATPAAPPAAPEILTAVGSDETVTVTWNLAATNGAPVTEYELHYSIDGF 5064

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
            +      + V   +   + + + DL    TY  ++ A +
Sbjct: 5065 ENDIDNIIVVATQETGPISYPVEDLENARTYSFKVRANS 5103



 Score =  122 bits (295), Expect = 8e-26
 Identities = 115/435 (26%), Positives = 179/435 (41%), Gaps = 29/435 (6%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE--ISRESVTIEWKP 1689
            I  L    S  +TI A N  G S  +   +     +KP+ P  +    IS   + + W  
Sbjct: 5993 IDGLDNGVSYTFTISARNDVG-SGPDSAPETVIPAAKPDVPTDLEAEAISGTEIDLTWLA 6051

Query: 1690 PLDDGGLELTKYAIEKHEPDNN-RWIKVADVD----RDVETYCIQKLNENCEYMFRVIAQ 1744
            P++ GGL +T Y IE+H+ D N   +    V      D  T+    L     Y +R+ A 
Sbjct: 6052 PVNTGGLGITGYLIERHDGDGNFATVTTTSVSVPPSTDDTTFNDTGLELGTTYTYRISAI 6111

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
               G   +  S+P    T  +VP           + N  + I W     NGGSP+  Y V
Sbjct: 6112 TGAGTGSS--SQP-ASDTTFNVPDKPTITEVN--VGNNELEIVWTAPTDNGGSPVTSYTV 6166

Query: 1805 EIK-QEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
            E K      W+         A    +  L     Y+FR+YA + +GTSLP  SD  +  G
Sbjct: 6167 EYKLTTDNTWQLSPVPPADGALDVTVIGLENGEEYEFRVYAISTVGTSLP--SD--VATG 6222

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-GKSWTKIVTVG 1919
               T PS P N V +   +  V+L W  P  +GGS I +Y++E+ + +    +T  V   
Sbjct: 6223 IPATTPSAPLNVVATRGDTE-VSLTWDLPADDGGSAIRDYLVEYASAELNLIYTPFVEPE 6281

Query: 1920 GSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
             S      +  +    E  FR+ A N +      +  +V  +  A     P+ P+   ++
Sbjct: 6282 ESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG---DYSAVTADSAAVPAGDPSTPVISTVI 6338

Query: 1979 GSN-IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
              + +V  +W   + +GG  L+ Y I       T  +E      + L +N+ DL     Y
Sbjct: 6339 ADDELVNLTWLASDANGGNNLV-YRIETSTDGFTTLIEDPAPTTSNLVYNVDDLQNGQEY 6397

Query: 2038 MIRIYARNEIGLSEP 2052
              RI A  + G S+P
Sbjct: 6398 SFRITAITDAGSSDP 6412



 Score =  122 bits (294), Expect = 1e-25
 Identities = 172/711 (24%), Positives = 267/711 (37%), Gaps = 74/711 (10%)

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
            E++ T LD P  P    +   D   + + W +PE+T    ++ Y +E +         V+
Sbjct: 7993 EVSTTTLDLPDEPTSLQVFA-DRGQLTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVE 8051

Query: 1432 NITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASET---TEYYKVIKETKIQSPTVEK 1486
            N    +T  +   L  N+SY +R   +     SD S+    T Y        +++   +K
Sbjct: 8052 NTDSDETIYTDSGLNDNTSYSYRVSTITAAGTSDPSQIVRGTTYGLPSAPLDLEADAKKK 8111

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYEN----RXXXXXXXX 1540
             ++   T P  D       GG P   +T Y+   KL T    + Y +    +        
Sbjct: 8112 KVRLSWTAPVND-------GGSP---ITDYKIEYKLATDTNWSVYADAERIKPQATVDSL 8161

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI 1599
                   ++  A N+ G   TS +V  Q KP +  +      Q+   G +  +    E  
Sbjct: 8162 TNSKIYQFRVSAVNEFGAGLTSSIV--QAKPSVAGATAAYNIQEIPSGQDVFLPHNAEDT 8219

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
                    +NG KL   K   I  K   S I +       +     + +       ++  
Sbjct: 8220 -------LENGGKLAGLK---IKPKNTLSEIAMTSTFTKDAPTGVTQEAKMYLKFELDFV 8269

Query: 1660 LKVYDKPSKPEGPV--IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
              V    S P G V  ++   S   V + W  P  DGG +++ Y IE+   DNN W  + 
Sbjct: 8270 EDVETDASVP-GQVTSVVATASAGKVELTWSAPDSDGGADISGYKIEQ-STDNNTWTVLE 8327

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
                    Y    L     Y +R+ A N  G   A +   +   T LDVP          
Sbjct: 8328 TTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASD---VASATPLDVPGPPRNLQTTP 8384

Query: 1778 XIDNESVYITW-FPS------EKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXARIQK 1828
               N  V + W  PS        NGGS I  Y V    +   WK             +  
Sbjct: 8385 --GNAQVTLAWDIPSTDGGITADNGGSIITGYVVHYAIDTNFWKTFNEEPITERTVDVTG 8442

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
            L+    Y+FR++A NE+G   P     +I +    T P +P    ++  +   + L W  
Sbjct: 8443 LTNGQNYKFRVFAVNEVGFLHPSLVSSEIPV----TVPERPWGLTITAPSQNQINLSWKT 8498

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVG------GSVHEHCIENIKEKDEIIFRISA 1942
            P  NGGS IT Y I+ KT+ GK  T  V         G+V+     N+       +R+  
Sbjct: 8499 PLDNGGSTITGYKIQ-KTI-GKPTTNSVWSDAPSGTLGTVNSWSDTNLIPGTTYSYRVI- 8555

Query: 1943 ENTVGVSLPT-ESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
              T+  ++P  +S S      AT  S P AP  L +   G  IV+  W  P  +GG P++
Sbjct: 8556 --TLTDAVPDGDSNSASGAIFATTLSVPGAPRNLTLEAEGKKIVI-DWVAPTSNGGTPIV 8612

Query: 2000 GYNIAIRDVTKTMW--MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             Y I   D   + W  ++     V +      ++     Y IR+YA N IG
Sbjct: 8613 NYLIQWSDNGGSKWNTLKRDASAVTSATVKSSNIVLGTEYQIRVYAENTIG 8663



 Score =  118 bits (285), Expect = 1e-24
 Identities = 110/418 (26%), Positives = 171/418 (40%), Gaps = 32/418 (7%)

Query: 1642 KYTIEASNTAG---TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
            ++TI A+N  G   T S   T   +  P+   G  +      + V +EW  P+ + G E+
Sbjct: 3307 EFTITATNEHGLTSTPSAPATATPFGPPNAVTG--LGATPGDKQVDLEWTEPVPNAGGEI 3364

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
              Y I   +P+ N  ++   ++   +   I  LN   EY F + A N  G +     +  
Sbjct: 3365 ASYTITVTDPNGNV-VQTITINAPADEANIDGLNNGVEYTFTITATNVNGVT----GDAA 3419

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-----GKKW 1813
             I TA+                N+SV ++W P + + GS I  Y ++   +     G   
Sbjct: 3420 TI-TAIPATVPLPPVLDSADRGNQSVTLSWTP-QFDQGSTITQYTIQYSSDNFQTTGTVV 3477

Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                        I  L+   TYQF++ A N  G S P      I   K  T P  P    
Sbjct: 3478 IGDDEALATSTTISGLTNGLTYQFQVIASNAFGPSDP----SNIKSAKPATFPDAP-TLD 3532

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGS--VHEHCIENI 1930
             ++  ++SV L WT P +NGG PI +Y +E+   +   S     T+ G+     + +  +
Sbjct: 3533 SADRGNQSVALSWT-PGNNGGEPIDSYHVEWSEDENFASILDTATISGNPPAESYTVTGL 3591

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
               D   FRI + N +  S P+   +V  +  AT PS P  P      G N V  SW  P
Sbjct: 3592 TNGDTYYFRIISSNVIDDSAPS---NVLSQTPATTPSEPLNPAA--EPGPNQVEVSWTLP 3646

Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              DGGA +  Y +         W E    + NT    I +L+    Y+  I+A N++G
Sbjct: 3647 ASDGGAEI-EYYVVRYSTDGGSWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHNDVG 3703



 Score =  115 bits (277), Expect = 1e-23
 Identities = 105/393 (26%), Positives = 156/393 (39%), Gaps = 30/393 (7%)

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREIS 1679
            IT         I  L       +TI A+N  G +    T+      + P  PV+   +  
Sbjct: 3382 ITINAPADEANIDGLNNGVEYTFTITATNVNGVTGDAATITAIPA-TVPLPPVLDSADRG 3440

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW---IKVADVDRDVETYCIQKLNENCE 1736
             +SVT+ W P  D G   +T+Y I+ +  DN +    + + D +    +  I  L     
Sbjct: 3441 NQSVTLSWTPQFDQGST-ITQYTIQ-YSSDNFQTTGTVVIGDDEALATSTTISGLTNGLT 3498

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y F+VIA N  G      S+P  IK+A                 N+SV ++W P   NGG
Sbjct: 3499 YQFQVIASNAFG-----PSDPSNIKSAKPATFPDAPTLDSADRGNQSVALSWTPGN-NGG 3552

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXX------XARIQKLSINTTYQFRIYARNEIGTSLP 1850
             PI  Y VE  ++                      +  L+   TY FRI + N I  S P
Sbjct: 3553 EPIDSYHVEWSEDENFASILDTATISGNPPAESYTVTGLTNGDTYYFRIISSNVIDDSAP 3612

Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
                  +      T PS+P N   +E     V + WT P S+GG+ I  Y++ + T  G 
Sbjct: 3613 ----SNVLSQTPATTPSEPLN-PAAEPGPNQVEVSWTLPASDGGAEIEYYVVRYST-DGG 3666

Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
            SWT+  T  G+     I+ +      +F I A N VG    ++  +      AT PS P 
Sbjct: 3667 SWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTA---TPATAPSAPQ 3723

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
              +     G   V+  W  P  +GGA +  Y +
Sbjct: 3724 NLVATPQTGQ--VLLVWEKPSSNGGATITSYTV 3754



 Score =  115 bits (276), Expect = 2e-23
 Identities = 103/414 (24%), Positives = 158/414 (38%), Gaps = 26/414 (6%)

Query: 1645 IEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            + A+N  G   S+  + +  +  P KP    +  +     VT+ W  P+++GG E+T Y 
Sbjct: 7781 VSAANAGGISNSTSPIPVSAFTIPGKPFD--LTTQFGDSQVTLLWSAPVNNGGEEITNYV 7838

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            IE    +   W    D      T  +  L    EY FRV A+N  G         +  KT
Sbjct: 7839 IEYSSDNGANWNVFDDGTSADPTATVTGLTNGQEYKFRVSAENIAGVG-------LPSKT 7891

Query: 1763 ALDVPSXXXXXXXXXXIDN--ESVYITW-FPSEKNGGSPIIDYKVEIKQEG---KKWKXX 1816
            A DVP+               +S+ ITW  P +  G + I  Y +E          +   
Sbjct: 7892 ASDVPATQSSRPTGLSATPALDSITITWNAPEDIGGATEISGYVIERSISSGFFNPYVDD 7951

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVS 1875
                        L   T Y +RI A   + +  P   D    +   TL  P +P +  V 
Sbjct: 7952 TGSALTSFVDTSLFSGTDYSYRIAAITLLPSGEPVVGDFSGEVSTTTLDLPDEPTSLQVF 8011

Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
                + +TL W +PE   G P+  Y IE ++   +  T +         +    + +   
Sbjct: 8012 ADRGQ-LTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVENTDSDETIYTDSGLNDNTS 8070

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDG 1994
              +R+S     G S P  SQ VR     T    P+APL++        V  SW  P  DG
Sbjct: 8071 YSYRVSTITAAGTSDP--SQIVR----GTTYGLPSAPLDLEADAKKKKVRLSWTAPVNDG 8124

Query: 1995 GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            G+P+  Y I  +  T T W      +    +  +  L+ +  Y  R+ A NE G
Sbjct: 8125 GSPITDYKIEYKLATDTNWSVYADAERIKPQATVDSLTNSKIYQFRVSAVNEFG 8178



 Score =  113 bits (272), Expect = 5e-23
 Identities = 111/445 (24%), Positives = 181/445 (40%), Gaps = 23/445 (5%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
            N+T    T+V  + +L       + I   N AG        +     + P  P  + E +
Sbjct: 6692 NVTPANSTAVT-VTDLINGFQYFFRISGVNIAGIGEPS-EFRATTPATLPSAPRDL-EAT 6748

Query: 1680 RE--SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCE 1736
            R+  SV + W  P D GG  L+ Y +E   P  + WIK  D     +T   +  L    +
Sbjct: 6749 RDNTSVHLTWNVPEDLGGAPLSAYMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQ 6808

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y FR+ A+N    ++   +   V  T    P+            N    ++W   E NGG
Sbjct: 6809 YQFRITAKN-TAITDFGPASDTVSATPATTPTAPRDLVVIAG--NNQATLSWNVPESNGG 6865

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTS 1853
              I DYK+EI+  G+ W           +   I  L+   TY+FR+ A N +    P  +
Sbjct: 6866 DSITDYKIEIRIAGQDWDVYDDGVSTTTQGIVIPNLTNGVTYEFRVTAINSVN---PGPA 6922

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT-VKGKSW 1912
             D +  GK  T P+ P+  VV    ++ + + WT+P +NGGS IT+Y++++ T     + 
Sbjct: 6923 SD-VVPGKPATIPTPPKKLVVIPGDTK-LDVTWTKPTNNGGSAITSYLVQYSTDGTFDAS 6980

Query: 1913 TKIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971
            T  VTV    +    I  ++    I  +++A N VG S P       +    ++ S    
Sbjct: 6981 TPSVTVTDLTNLMVTISGLENDVPIHVQVTAINGVGSSGPAGP----VIGVPSLGSSSPV 7036

Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031
             L    +    V  SW  P+  G   L G+ +   D    +       D   L F    L
Sbjct: 7037 GLFADAISDTEVFVSWSPPQELGDRTLEGFVLERLDANGNVLETFTINDPTKLDFTDTGL 7096

Query: 2032 SENHTYMIRIYARNEIGLSEPLESD 2056
                TY  ++ A   +  ++ ++SD
Sbjct: 7097 LPGTTYKYQVSALLSLEGADTVQSD 7121



 Score =  111 bits (267), Expect = 2e-22
 Identities = 96/345 (27%), Positives = 140/345 (40%), Gaps = 25/345 (7%)

Query: 1669 PEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETY 1726
            P  P  +  E   E V + W PP  +GG  +T Y IE +  D N W    D    D    
Sbjct: 1280 PGAPTNLTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFNDGTSTDTTDV 1337

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             +  L     Y FRV A N  G  +A +   I   T   VP             N  VY+
Sbjct: 1338 AVTGLTNGQSYDFRVSAVNTEGTGDASD---IATATPAGVPDAPVIDEALG--GNGQVYL 1392

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
            TW     N G+ I DY +E+  +G  W+             +  L    TY FR+ A N 
Sbjct: 1393 TW-EHPPNNGAAITDYIIEV-NDGNGWEVFNDGTSTNRFVTVDNLENGETYSFRVKAVNS 1450

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
             G   P+++    T   T T P         +S    V + W  P  +GGS I++Y I++
Sbjct: 1451 AGEG-PFSTPVTATPSSTATAPFL-HTLTPGDS---EVFVDWDAPNDDGGSTISSYEIQY 1505

Query: 1905 KT-VKGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             T       T  VTV G+  + E+ +  +       FR+ A N  G S P+   +     
Sbjct: 1506 STDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENGSSPPSNLDTA---T 1562

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
             AT+P  P       + G+  V  +W TP ++GG+P+  Y I ++
Sbjct: 1563 PATIPDAPVIDPAQTVTGNEFVTIAWSTP-YNGGSPITHYVIQVK 1606



 Score =  110 bits (265), Expect = 4e-22
 Identities = 113/416 (27%), Positives = 173/416 (41%), Gaps = 43/416 (10%)

Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD------NNRWIKVADVDRDVE-T 1725
            ++   +S   + + W+ P DDGG  ++ Y IE+   D          I V +     + T
Sbjct: 5437 LVATTLSGTEIQLVWQAPSDDGGRAVSGYLIERLGTDGAFAEVTTTTIPVPESPTASDTT 5496

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
            +    L+    Y +RV A N +G  +  +++     T  D PS            NE V 
Sbjct: 5497 FTDTGLSLGTTYTYRVSAVNVLGTGDPSDTDD---ATTFDYPSAPVLDAAIR--GNELVT 5551

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR----IQKLSINTTYQFRIY 1840
            + W     NGG+P+ +Y  + +  G   W                   L+   TY+FR+ 
Sbjct: 5552 LQWTAPSDNGGTPLENYIAQFRLLGASDWTTFDDEISLSPTEINVDSGLTNGQTYEFRVI 5611

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N +G S        +   K  T PS+P   V +E   R V+L W EPE +GG  I +Y
Sbjct: 5612 AENSVGES----EASNVLQAKPATTPSKPLQ-VGAEFGDRQVSLTWLEPEISGGEDIFDY 5666

Query: 1901 IIEFKTVK---GKSWTKIVTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTES 1954
            I+EF+        SW       G V+ +    I  +       FR+SAEN VGV    + 
Sbjct: 5667 ILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAENDVGVG---DV 5723

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-------IRD 2007
              V     AT  + PTA     + G+ I + SW  P+  GG  + GY I          D
Sbjct: 5724 SDVATATPATASNAPTALSATAISGTEITL-SWIAPQNTGGFAITGYLIERHDGDGNFDD 5782

Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI--GLSEPLESDEPFKV 2061
            VT T+ + +  +  +T  F    LS+  TY  R+ A  ++  G++   +SD  F V
Sbjct: 5783 VT-TLSVSLPPLPTDT-TFTDTGLSQGTTYTYRVSAVTQLGPGIASGTDSDTTFDV 5836



 Score =  109 bits (262), Expect = 8e-22
 Identities = 151/707 (21%), Positives = 265/707 (37%), Gaps = 61/707 (8%)

Query: 1384 PGKPNIL--EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ--TS 1439
            PGKP  L  +   S + + W  P N G   I  YV+EY   +   W    + T      +
Sbjct: 7804 PGKPFDLTTQFGDSQVTLLWSAPVNNGGEEITNYVIEYSSDNGANWNVFDDGTSADPTAT 7863

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN--E 1497
            +  L     Y+FR  A N   +   S+T       + ++    +    L +IT   N  E
Sbjct: 7864 VTGLTNGQEYKFRVSAENIAGVGLPSKTASDVPATQSSRPTGLSATPALDSITITWNAPE 7923

Query: 1498 DIE-LTCIFGGVPQPKVTW-----YRD--GKKLKT-AKATYENRXXXXXXXXXXXXXXXY 1548
            DI   T I G V +  ++      Y D  G  L +    +  +                 
Sbjct: 7924 DIGGATEISGYVIERSISSGFFNPYVDDTGSALTSFVDTSLFSGTDYSYRIAAITLLPSG 7983

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            + +  +  GEV T+  + +  +P    S +    + ++   W+      G+P   V+ Y+
Sbjct: 7984 EPVVGDFSGEVSTT-TLDLPDEPT---SLQVFADRGQLTLTWIDPEDTSGLP---VLGYE 8036

Query: 1609 NGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--VYD 1664
               +    +   I   T    ++     L  + S  Y +     AGTS     ++   Y 
Sbjct: 8037 IERRSTGAEFTTIVENTDSDETIYTDSGLNDNTSYSYRVSTITAAGTSDPSQIVRGTTYG 8096

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
             PS P    +  +  ++ V + W  P++DGG  +T Y IE     +  W   AD +R   
Sbjct: 8097 LPSAPLD--LEADAKKKKVRLSWTAPVNDGGSPITDYKIEYKLATDTNWSVYADAERIKP 8154

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
               +  L  +  Y FRV A N   F   L S   +++    V               + V
Sbjct: 8155 QATVDSLTNSKIYQFRVSAVNE--FGAGLTSS--IVQAKPSVAGATAAYNIQEIPSGQDV 8210

Query: 1785 YITWFPSE--KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
            ++     +  +NGG  +   K++ K                   +      T + ++Y +
Sbjct: 8211 FLPHNAEDTLENGGK-LAGLKIKPKN------TLSEIAMTSTFTKDAPTGVTQEAKMYLK 8263

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
             E    L +  D    +    + P Q  + V + S  + V L W+ P+S+GG+ I+ Y I
Sbjct: 8264 FE----LDFVED----VETDASVPGQVTSVVATASAGK-VELTWSAPDSDGGADISGYKI 8314

Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            E ++    +WT + T      ++   +++      +RISA N  G    ++  S      
Sbjct: 8315 E-QSTDNNTWTVLETTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASDVASA---TP 8370

Query: 1963 ATVPSPP----TAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
              VP PP    T P   ++ +  +I  T  G    +GG+ + GY +    +    W    
Sbjct: 8371 LDVPGPPRNLQTTPGNAQVTLAWDIPSTDGGITADNGGSIITGY-VVHYAIDTNFWKTFN 8429

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP-LESDEPFKVIP 2063
            +  +     ++  L+    Y  R++A NE+G   P L S E    +P
Sbjct: 8430 EEPITERTVDVTGLTNGQNYKFRVFAVNEVGFLHPSLVSSEIPVTVP 8476



 Score =  109 bits (261), Expect = 1e-21
 Identities = 115/461 (24%), Positives = 185/461 (40%), Gaps = 42/461 (9%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWKPP 1690
            I  L+   + ++ + A N      V  T+ V    + P  P  ++       V++ W   
Sbjct: 4891 IGNLENGVTYEFRVYAQNDIDDGPVSTTISV-TPATVPTPPTNLIPTFGSTQVSLGWTAS 4949

Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
             DDGG ++  Y +E      + W    D   DV    +  L     Y FRV A N VG  
Sbjct: 4950 SDDGGSDIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVG-- 5007

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
                S+P  +K A                 +E+V +TW  +  N G+P+ +Y++    +G
Sbjct: 5008 ---NSDPSEVKEATPAAPPAAPEILTAVGSDETVTVTWNLAATN-GAPVTEYELHYSIDG 5063

Query: 1811 KKWKXXXXXXXXXAR-------IQKLSINTTYQFRIYARNEIGTSLPYTSD-DKITIGKT 1862
             +                    ++ L    TY F++ A N I +  P+++  D +     
Sbjct: 5064 FENDIDNIIVVATQETGPISYPVEDLENARTYSFKVRA-NSIASFGPFSNTLDAV----P 5118

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKGKSWTKIVTVGG 1920
             T P+ P +   +      VTL+W +P+ NGGS IT+Y++E+   +      ++ VT   
Sbjct: 5119 FTTPNAPTDLEATRGNG-EVTLQWNKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSD 5177

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
                  I  +       FR+ A N  G    ++   +     ATVP+ PT  L+    G 
Sbjct: 5178 DPITTVISGLDNGTLYSFRVKAVNAAGEGALSD---IATATPATVPAAPT--LDTATPGD 5232

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-----MW--MEVGKVDVNTL-KFNIRDLS 2032
              V+  W   E  GG  L+ Y I  R++  T      W   + G   VN L    I DL+
Sbjct: 5233 ESVLLGWTPSENTGGDALIDYLIQFRELDATNDAESNWTTFDEGNGGVNVLTSITIDDLT 5292

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073
               TY  R++A+N +    P +S  P  V+  E S A   P
Sbjct: 5293 NGVTYEFRVFAKNTV----PGQS-LPSNVLSAEPSSAPSVP 5328



 Score =  106 bits (254), Expect = 8e-21
 Identities = 118/471 (25%), Positives = 177/471 (37%), Gaps = 44/471 (9%)

Query: 1630 IRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
            + +  L    + ++ + A N    G +S   T +       P G +    IS   + +EW
Sbjct: 4299 VTVTGLTNGLTYEFRVSAENAVDVGPTSNVATARPATLSDAPTG-LDAEAISDTEIDLEW 4357

Query: 1688 KPPLDDGGLELTKYAIEKH-EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
              PL  GG  +  Y IE+  E + +  I VAD      TY    L+    Y +RV A   
Sbjct: 4358 NAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAAITD 4417

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
             G  +   +      T  DVP             N  V + W     NGG+PI  Y++E 
Sbjct: 4418 AGVGDTSSTAEA---TTFDVPGKTEIISLTPG--NAQVEVEW-SEPTNGGTPITGYRIEY 4471

Query: 1807 KQEGKKWKXXXXXXXX-------XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
                                    A I  L+   TY FR+ A N +    P +  D  T 
Sbjct: 4472 TTNETDANNGVFTSSVDVAASPLSATINNLNNGDTYYFRVTATNSVDFGEP-SDVDSATP 4530

Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTV 1918
             +    P  P + V +    + VT+ +T P  +GGS I +Y IE+    G +W +     
Sbjct: 4531 ARA---PDAPTDLVATLGDGQ-VTIGFTPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQT 4586

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
              +  E  +  +    E +FR  A N VG   P +      E  A +   PT  +  R  
Sbjct: 4587 ESTTPEITVTGLNNGQEYLFRAVAVNGVG---PGDESVPVAETPAALSGNPTDLVATR-- 4641

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRD----------VTKTMWMEVGKVDVNTLKFNI 2028
            G+  V  +W  P   GG P+  Y +   D           ++T+  E   V  NT+   I
Sbjct: 4642 GNTQVSLTWAAPAVTGGVPVTSYIVEYTDDANGDFGANPSSQTVTSETLPVPTNTI---I 4698

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESD--EPFKVIPGEGSHADEEPGEQT 2077
              L    TY  R+ A N  G S P  +D  +P   +P   +  D +P   T
Sbjct: 4699 NGLQNGVTYTFRVIAVNTAGPSGPSNTDTAKP-ATVPDAPTFDDPQPSAGT 4748



 Score =  106 bits (254), Expect = 8e-21
 Identities = 113/477 (23%), Positives = 190/477 (39%), Gaps = 41/477 (8%)

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            V+ Y + +   + +   +T  +      I  L       + ++A N AG  ++   +   
Sbjct: 5156 VVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAVNAAGEGALS-DIATA 5214

Query: 1664 DKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPD-----NNRWIKVA 1717
               + P  P +       ESV + W P  + GG  L  Y I+  E D      + W    
Sbjct: 5215 TPATVPAAPTLDTATPGDESVLLGWTPSENTGGDALIDYLIQFRELDATNDAESNWTTFD 5274

Query: 1718 DVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            + +  V    +  I  L     Y FRV A+N V   ++L S  +  + +   PS      
Sbjct: 5275 EGNGGVNVLTSITIDDLTNGVTYEFRVFAKNTVP-GQSLPSNVLSAEPS-SAPSVPRDLR 5332

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG------KKWKXXXXXXXXXARIQK 1828
                I +E V I+W     NGG  I+ Y V+   +       ++           A +  
Sbjct: 5333 VTN-IGDEFVSISWLAPADNGGDDIVGYTVQYSDDNFTTISTQEIVPVSGVLPTDATVSS 5391

Query: 1829 LSINTTYQFRIYARNE-IGTSLPYTSD--DKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            L     YQFR+ A NE     +P +SD  D +T G   T P  P + V +  +   + L 
Sbjct: 5392 LENGVDYQFRVIAHNEDDDPQIPDSSDPSDPVT-GTPGTVPGIPTDLVATTLSGTEIQLV 5450

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN--------IKEKDEII 1937
            W  P  +GG  ++ Y+IE     G ++ ++ T    V E    +        +       
Sbjct: 5451 WQAPSDDGGRAVSGYLIERLGTDG-AFAEVTTTTIPVPESPTASDTTFTDTGLSLGTTYT 5509

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGA 1996
            +R+SA N +G   P+++        AT    P+AP L+  + G+ +V   W  P  +GG 
Sbjct: 5510 YRVSAVNVLGTGDPSDTDD------ATTFDYPSAPVLDAAIRGNELVTLQWTAPSDNGGT 5563

Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNI-RDLSENHTYMIRIYARNEIGLSE 2051
            PL  Y    R +  + W     ++ ++  + N+   L+   TY  R+ A N +G SE
Sbjct: 5564 PLENYIAQFRLLGASDWTTFDDEISLSPTEINVDSGLTNGQTYEFRVIAENSVGESE 5620



 Score =  104 bits (250), Expect = 2e-20
 Identities = 159/693 (22%), Positives = 259/693 (37%), Gaps = 67/693 (9%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICW 1401
            S TI  + N D   +++   N+    +   +V        P  P   +  +    + I +
Sbjct: 4495 SATINNLNNGDTYYFRVTATNSVDFGEPS-DVDSATPARAPDAPTDLVATLGDGQVTIGF 4553

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT---SIQNLKTNSSYRFRAYAVNE 1458
              P   G S II Y +EY   +   W    + T++ T   ++  L     Y FRA AVN 
Sbjct: 4554 TPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQTESTTPEITVTGLNNGQEYLFRAVAVNG 4613

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT----CIFGGVPQPK-V 1513
            V   D S        +   +  +     P   + T  N  + LT     + GGVP    +
Sbjct: 4614 VGPGDES--------VPVAETPAALSGNPTDLVATRGNTQVSLTWAAPAVTGGVPVTSYI 4665

Query: 1514 TWYRD------GKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
              Y D      G    +   T E                    ++ IA N  G    S  
Sbjct: 4666 VEYTDDANGDFGANPSSQTVTSETLPVPTNTIINGLQNGVTYTFRVIAVNTAGPSGPSNT 4725

Query: 1565 VGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYN 1620
               +   V      D  Q     VG  W  T    G  P E   I Y + N     +  +
Sbjct: 4726 DTAKPATVPDAPTFDDPQPSAGTVGLSW--TPGNTGGEPIERYRIDYTSANSFVEGQYQS 4783

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREI 1678
                  T+V+ I++L+     ++ I A N    G  S  +T    D PS+  G  +  + 
Sbjct: 4784 EFVTHPTTVVDIEDLENGVEYQFRISAENEVGFGDPSAPITATPVDGPSQVTG--LSGQR 4841

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
                V++ W  P  DGG+ +  Y IE   +   N   +       V    I  L     Y
Sbjct: 4842 GNGEVSLSWSEPF-DGGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLENGVTY 4900

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             FRV AQN +   +   S  I + T   VP+            +  V + W  S  +GGS
Sbjct: 4901 EFRVYAQNDI--DDGPVSTTISV-TPATVPT--PPTNLIPTFGSTQVSLGWTASSDDGGS 4955

Query: 1798 PIIDYKVEIKQEGKK-WKXXXXXXXX--XARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
             I DY VE K + +  W+           A +  L+    Y+FR+ A N++G S P    
Sbjct: 4956 DIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVGNSDP---- 5011

Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG--KSW 1912
             ++       PP+ P   + +  +  +VT+ W    +N G+P+T Y + + ++ G     
Sbjct: 5012 SEVKEATPAAPPAAP-EILTAVGSDETVTVTWNLAATN-GAPVTEYELHY-SIDGFENDI 5068

Query: 1913 TKIVTVG----GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
              I+ V     G +  + +E+++      F++ A N++    P  +    +    T P+ 
Sbjct: 5069 DNIIVVATQETGPI-SYPVEDLENARTYSFKVRA-NSIASFGPFSNTLDAVP--FTTPNA 5124

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
            PT  LE    G+  V   W  P+++GG+ +  Y
Sbjct: 5125 PT-DLEATR-GNGEVTLQWNKPDFNGGSLITSY 5155



 Score =  103 bits (246), Expect = 7e-20
 Identities = 121/461 (26%), Positives = 173/461 (37%), Gaps = 43/461 (9%)

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE--VTLKVYDKPSKPEGPVIMREIS 1679
            T    T  + I EL       + I A N  G   +   VT      PS P+  V   +  
Sbjct: 3673 TANGNTFSLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTATPATAPSAPQNLVATPQTG 3732

Query: 1680 RESVTIEWKPPLDDGGLELTKYAI-----EKHEPDNNRWIKVADVDR---DVETYCIQKL 1731
            +  V + W+ P  +GG  +T Y +     E  +P+N   + +  VD     V T  +  L
Sbjct: 3733 Q--VLLVWEKPSSNGGATITSYTVKWTPGETFDPNNFESVTITSVDGVAPPVTTTTVTGL 3790

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
                 Y F V A N     E   S P    T  + P            D ES  I W   
Sbjct: 3791 TNGQTYTFVVTATNSA--DEGPASNPATT-TPANPPDAPVLVSVTSDDDQEST-IVW-NQ 3845

Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT---------YQFRIYAR 1842
              NGGSPIIDY VE    G             A      I TT         Y FR+ AR
Sbjct: 3846 PANGGSPIIDYLVEYTSTGAFNPQDTESVVITAPQNNDPITTTIDGLDNGVEYSFRVTAR 3905

Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
            N + +  P      +  G   T P  PR+  V++S +  V+L W  P  +GG  +  Y +
Sbjct: 3906 NLVDSGDP----SNVLTGIPSTNPLPPRDLQVTDSGNAFVSLSWLTPLDDGGDDLVGYTV 3961

Query: 1903 EFK--TVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAEN-TVGVSLPTESQSVR 1958
            ++        S  +I+ V G +     I  +    E  FR+ A N   G +  T+  S  
Sbjct: 3962 QYSDDNFATISTQEIIPVDGVLPTTATISGLDNGSEYKFRVIAHNEDDGDNDDTDDSSDP 4021

Query: 1959 LEKHATVPSP-PTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
                +  PS  P AP  LE+   G+  V  SW    +DGG+ L  Y +   D    ++ E
Sbjct: 4022 SNTVSATPSTVPDAPTLLEVTDHGNGFVSLSWTASVFDGGSTLNTYVVEYTDDENGVFDE 4081

Query: 2016 ------VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
                  +G  +    +  +  L     Y  R+ A N+ G S
Sbjct: 4082 PPSSVIIGDDETLDTQATVSGLDNGVEYTFRVKATNDNGSS 4122



 Score =  101 bits (242), Expect = 2e-19
 Identities = 107/446 (23%), Positives = 187/446 (41%), Gaps = 33/446 (7%)

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPVIMRE 1677
            YN      T+ + +  L+     K+ + A N  G ++   + +V   P++ P+ PVI   
Sbjct: 1711 YNDGQSIDTTDVPVTGLENGVLHKFRVYAVNALGNATP--SNEVEATPARAPDAPVITEL 1768

Query: 1678 ISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE--TYCIQKLNEN 1734
             + +  + + W  P DDGG  + +Y +E    D +  +    +  +    TY +  L   
Sbjct: 1769 NAGDGQIEVIWSTP-DDGGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNG 1827

Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
              Y FRVIA N V      ES+P  +++A+ V            + + S+ ++W  +  +
Sbjct: 1828 DTYYFRVIAINDVD-----ESDPSDVESAIPVTVPAKPVLNTPVVGDSSLTVSW-SAPND 1881

Query: 1795 GGSPIIDYKVEIKQE--GKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851
            GGSP+  Y + I     G  +               +L+   TY F + A N  G+S P 
Sbjct: 1882 GGSPLTGYTLSITDVTGGNTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDP- 1940

Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
               D +T G  +  P Q  + + +ES  + V L WT+P+ NG   IT+Y IE +   G  
Sbjct: 1941 --SDAVT-GIPIGAPGQIDD-LGAESGDKQVDLTWTQPDLNGSGDITSYTIEVRDSSGTL 1996

Query: 1912 WTKIVTVGGS----VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
               IV  G           +  +   +   F I+A N   ++  T S  V     +T   
Sbjct: 1997 VDTIVITGTGGNPPATSTTVTGLTNNETYSFTITATNENNLT-STPSDPVT----STPLG 2051

Query: 1968 PPTAPLEIRMV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKVDVNTL 2024
             P AP  +    G   V  +W  P+ +G   ++ Y + +RD +  +   + +G  +  T 
Sbjct: 2052 APAAPGNLTPTPGDKQVDLTWTQPDLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTT 2111

Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLS 2050
             + +  L+ +  Y   + A NE  L+
Sbjct: 2112 SYLVTGLTNSVNYTFEVTATNENNLT 2137



 Score =  101 bits (241), Expect = 3e-19
 Identities = 108/441 (24%), Positives = 176/441 (39%), Gaps = 31/441 (7%)

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREISRES-VTIEWKPPLD 1692
            L    +  +TI A+N  G +S+  +L V   P  P  PV  ++ IS +  V + W  P+ 
Sbjct: 2417 LTSGETYSFTITATNGHGLTSIP-SLPVTATPFGPPNPVTDLQAISGDKQVDLIWTQPVP 2475

Query: 1693 DGGLELTKYAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
            + G  +  Y I   +P  N  + I + D +    +  I  LN   EY F +IA N    S
Sbjct: 2476 NAGGAIETYTITVRDPSGNVVQTIVIGDDEPLATSVNIDGLNNGVEYTFEIIATN----S 2531

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-E 1809
              L+S  +        P            D E V I W   E N    I  Y + +    
Sbjct: 2532 NNLDSSAVSTTEIPFGPPGVIDTPTADAGDGE-VTIDWEEPELNDSGAIETYTITVTDPS 2590

Query: 1810 GKKWKXXXX----XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            G   +               +  L+    Y F I A NE   +L  T    +T    +T 
Sbjct: 2591 GNVVQTIIIGDDEALATSTTVTGLTNGVEYSFTITATNE--NNLTSTPSTPVT-ATPITT 2647

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            P+ P N   +  +   + L WT P +N     +T Y IE +  +G++   I+        
Sbjct: 2648 PNAPTNLDATALSDTEIELTWTAPPTNPQFGTLTGYQIE-RQAEGEADFTIIVADTQTTA 2706

Query: 1925 HCIENIKEKD--EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
                ++      E  +R+SA  T G+    ++ S       TVP+ P   L   +VG + 
Sbjct: 2707 TTFNDLGLSSGVEYTYRVSAITTAGIG---DASSPASATTFTVPAKPV--LNEPVVGDSS 2761

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            +  SW  P  +GG P+ GY ++I ++T  + ++   +  +   +    L+  + Y   + 
Sbjct: 2762 LTVSWSKPS-NGGTPITGYTLSITNLTTGIDLDDVSLSADATDYTASLLTNGNEYSFTLV 2820

Query: 2043 ARNEIGLSEPLESDEPFKVIP 2063
            A N +G S   ES +P   IP
Sbjct: 2821 AINSVGSS---ESSDPVTGIP 2838



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 28/347 (8%)

Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768
            + N  +    V  D  ++ I+ L     Y FR+ A+  +G+S    S  +V  T   +P 
Sbjct: 6489 NGNSSVTSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYS---ASSNVVTFTPATIPG 6545

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSP----IIDYKVEIKQEGKKWKXXX--XXXXX 1822
                        N  V +T+     NGG      +I Y+++   E   +           
Sbjct: 6546 --APTPLSAQFGNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTST 6603

Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
               +  L+    Y FR+ A NE+G S P T+       K  T P  P + +  +  ++ V
Sbjct: 6604 TVTVTDLTNGEVYDFRVIAVNEVGQSDPATAS-----AKPATTPGAP-DALQLDFANQLV 6657

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI---VTVGGSVHEHCIENIKEKDEIIFR 1939
            +L+W  P  +GG  I +YI+E+ ++    W      VT   S     + ++    +  FR
Sbjct: 6658 SLEWAVPTDDGGDEIDDYIVEY-SLDTSEWIVFPDNVTPANST-AVTVTDLINGFQYFFR 6715

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            IS  N  G+  P+E    R    AT+PS P   LE     +++ +T W  PE  GGAPL 
Sbjct: 6716 ISGVNIAGIGEPSE---FRATTPATLPSAP-RDLEATRDNTSVHLT-WNVPEDLGGAPLS 6770

Query: 2000 GYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARN 2045
             Y +      ++ W++ G  +        +  L+    Y  RI A+N
Sbjct: 6771 AYMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQYQFRITAKN 6817



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 108/453 (23%), Positives = 169/453 (37%), Gaps = 36/453 (7%)

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGP 1672
            EN       T+   + + I  L    +  + + A+N      V  TL    KP+  P  P
Sbjct: 4181 ENTVSEVFDTEPLPTTVTIDSLTNGVTYTFRVFATNIEDNGPVSNTLDA--KPATVPTKP 4238

Query: 1673 VIMR-EISRESVTIEWKPPLDDGGLELTKYAIE---KHEPDNNRWIKVADVDRDVET--- 1725
            + +  E     V ++W+ P D+GG E+  Y IE     +     W    +    V T   
Sbjct: 4239 LQLNAEFGNLLVILDWQLPADNGGEEIIDYIIEYRLASQIPEATWQVFDEGVGGVNTNLF 4298

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
              +  L     Y FRV A+N V              T  D P+          I +  + 
Sbjct: 4299 VTVTGLTNGLTYEFRVSAENAVDVGPTSNVATARPATLSDAPT----GLDAEAISDTEID 4354

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI----QKLSINTTYQFRIYA 1841
            + W      GG+ I  Y++E + EG+            A        L   T+Y +R+ A
Sbjct: 4355 LEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAA 4414

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
              + G       D   T   T          +     +  V ++W+EP +NGG+PIT Y 
Sbjct: 4415 ITDAG-----VGDTSSTAEATTFDVPGKTEIISLTPGNAQVEVEWSEP-TNGGTPITGYR 4468

Query: 1902 IEFKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
            IE+ T         +T  V V  S     I N+   D   FR++A N+V    P++  S 
Sbjct: 4469 IEYTTNETDANNGVFTSSVDVAASPLSATINNLNNGDTYYFRVTATNSVDFGEPSDVDS- 4527

Query: 1958 RLEKHATVPSPPTAPLE-IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
                 AT    P AP + +  +G   V   +  P  DGG+ ++ Y I         W E 
Sbjct: 4528 -----ATPARAPDAPTDLVATLGDGQVTIGFTPPVEDGGSDIIDYYIEYSVDNGDNWFEF 4582

Query: 2017 G-KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              + +  T +  +  L+    Y+ R  A N +G
Sbjct: 4583 NDQTESTTPEITVTGLNNGQEYLFRAVAVNGVG 4615



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 114/453 (25%), Positives = 166/453 (36%), Gaps = 44/453 (9%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690
            I  L    + ++ + A N  G   V +V        S     +    IS   +T+ W  P
Sbjct: 5699 ITGLTNGQTYEFRVSAENDVGVGDVSDVATATPATASNAPTALSATAISGTEITLSWIAP 5758

Query: 1691 LDDGGLELTKYAIEKHEPDNN------RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
             + GG  +T Y IE+H+ D N        + +  +  D  T+    L++   Y +RV A 
Sbjct: 5759 QNTGGFAITGYLIERHDGDGNFDDVTTLSVSLPPLPTDT-TFTDTGLSQGTTYTYRVSAV 5817

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
              +G   A  ++     T  DVP             N  V ++W     N G+ I  Y V
Sbjct: 5818 TQLGPGIASGTDS---DTTFDVPDKPEITSADR--GNTQVDLSW-TEPANNGAAITAYLV 5871

Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSI-------NTTYQFRIYARNEIGTSLPYTSDDKI 1857
            +   +G             A + +LS           Y FRI A N +G S P    D +
Sbjct: 5872 QYSDDGTFDNTTPSVTLATADLTELSTTIDGLENGEEYSFRIIAINSVGQSDP---SDIV 5928

Query: 1858 TIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
                T TP + P    ++ +T     VTL WT P  +GGS + +Y I   T+     T  
Sbjct: 5929 ----TATPATFPDAPTITSATFGDGQVTLTWTGPTEDGGSDVLDYTI---TITSSLGTDT 5981

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
            + V  +     I+ +       F ISA N VG    +  ++V     A  P  PT  LE 
Sbjct: 5982 LVVPNTPFTRLIDGLDNGVSYTFTISARNDVGSGPDSAPETV---IPAAKPDVPT-DLEA 6037

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD-------VTKTMWMEVGKVDVNTLKFNI 2028
              +    +  +W  P   GG  + GY I   D       VT T        D  T     
Sbjct: 6038 EAISGTEIDLTWLAPVNTGGLGITGYLIERHDGDGNFATVTTTSVSVPPSTDDTTFNDTG 6097

Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
             +L   +TY I        G S    SD  F V
Sbjct: 6098 LELGTTYTYRISAITGAGTGSSSQPASDTTFNV 6130



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 110/449 (24%), Positives = 173/449 (38%), Gaps = 43/449 (9%)

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPV-IMREISRESVTIEWKPPLD 1692
            L    + ++ + A N+ G S     L+   KP+  P  P+ +  E     V++ W  P  
Sbjct: 5600 LTNGQTYEFRVIAENSVGESEASNVLQA--KPATTPSKPLQVGAEFGDRQVSLTWLEPEI 5657

Query: 1693 DGGLELTKYAIE---KHEPDNNRWIKVADVDRDVET---YCIQKLNENCEYMFRVIAQNP 1746
             GG ++  Y +E     +     W    +    V T     I  L     Y FRV A+N 
Sbjct: 5658 SGGEDIFDYILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAEND 5717

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
            VG  +  +       TA + P+          I    + ++W   +  GG  I  Y +E 
Sbjct: 5718 VGVGDVSDVATATPATASNAPT----ALSATAISGTEITLSWIAPQNTGGFAITGYLIER 5773

Query: 1807 KQEGKKWKXXXXXXXXXARIQK--------LSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
                  +            +          LS  TTY +R+ A  ++G  +   +D    
Sbjct: 5774 HDGDGNFDDVTTLSVSLPPLPTDTTFTDTGLSQGTTYTYRVSAVTQLGPGIASGTDS--- 5830

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK---TVKGKS-WTK 1914
               T   P +P     ++  +  V L WTEP +N G+ IT Y++++    T    +    
Sbjct: 5831 -DTTFDVPDKP-EITSADRGNTQVDLSWTEP-ANNGAAITAYLVQYSDDGTFDNTTPSVT 5887

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            + T   +     I+ ++  +E  FRI A N+VG S P++   +     AT P  PT  + 
Sbjct: 5888 LATADLTELSTTIDGLENGEEYSFRIIAINSVGQSDPSD---IVTATPATFPDAPT--IT 5942

Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034
                G   V  +W  P  DGG+ +L Y I I     T  + V       L   I  L   
Sbjct: 5943 SATFGDGQVTLTWTGPTEDGGSDVLDYTITITSSLGTDTLVVPNTPFTRL---IDGLDNG 5999

Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             +Y   I ARN++G S P     P  VIP
Sbjct: 6000 VSYTFTISARNDVG-SGP--DSAPETVIP 6025



 Score = 93.1 bits (221), Expect = 8e-17
 Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 48/441 (10%)

Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPVIMREI-SRESVTIEWKPPLDDGGLELT 1699
            +YT     T    S   + +V + P++ P+ P +   +   ESVT+ W P   DGG +LT
Sbjct: 4108 EYTFRVKATNDNGSSGYSNEVTETPARAPDAPTLDSAVRGDESVTLSWTPGF-DGGSDLT 4166

Query: 1700 KYAIEK-----HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN-----PVGF 1749
            +Y ++       +P+N    +V D +    T  I  L     Y FRV A N     PV  
Sbjct: 4167 QYTVQYTPTGIFDPENT-VSEVFDTEPLPTTVTIDSLTNGVTYTFRVFATNIEDNGPV-- 4223

Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809
            S  L+++P  + T                  N  V + W     NGG  IIDY +E +  
Sbjct: 4224 SNTLDAKPATVPT--------KPLQLNAEFGNLLVILDWQLPADNGGEEIIDYIIEYRLA 4275

Query: 1810 GK----KWK-----XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             +     W+                +  L+   TY+FR+ A N +    P TS+  +   
Sbjct: 4276 SQIPEATWQVFDEGVGGVNTNLFVTVTGLTNGLTYEFRVSAENAVDVG-P-TSN--VATA 4331

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
            +  T    P        +   + L+W  P   GG+ I  Y IE +      +T IV   G
Sbjct: 4332 RPATLSDAPTGLDAEAISDTEIDLEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTG 4391

Query: 1921 SVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
            S    +    +       +R++A    GV   T S +    +  T   P    +     G
Sbjct: 4392 SADTTYSDTGLDRGTSYTYRVAAITDAGVG-DTSSTA----EATTFDVPGKTEIISLTPG 4446

Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAI----RDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
            +  V   W  P  +GG P+ GY I       D    ++     V  + L   I +L+   
Sbjct: 4447 NAQVEVEWSEPT-NGGTPITGYRIEYTTNETDANNGVFTSSVDVAASPLSATINNLNNGD 4505

Query: 2036 TYMIRIYARNEIGLSEPLESD 2056
            TY  R+ A N +   EP + D
Sbjct: 4506 TYYFRVTATNSVDFGEPSDVD 4526



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 91/393 (23%), Positives = 146/393 (37%), Gaps = 21/393 (5%)

Query: 1666 PSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
            P  P  P  +  I S   V I W    D+    + +Y +E    D   W+ V + D +V 
Sbjct: 7709 PDPPGTPTNLSYIGSDRRVDITW----DESTGTVDRYLLEFSLNDGEEWLIVEEKDDNVP 7764

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
            ++    +     Y+ RV A N  G S +    P+   +A  +P             +  V
Sbjct: 7765 SFSKDGMVNGKVYLIRVSAANAGGISNSTSPIPV---SAFTIPGKPFDLTTQ--FGDSQV 7819

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX--XARIQKLSINTTYQFRIYA 1841
             + W     NGG  I +Y +E   + G  W            A +  L+    Y+FR+ A
Sbjct: 7820 TLLWSAPVNNGGEEITNYVIEYSSDNGANWNVFDDGTSADPTATVTGLTNGQEYKFRVSA 7879

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP-ITNY 1900
             N  G  LP     K       T  S+P     + +   S+T+ W  PE  GG+  I+ Y
Sbjct: 7880 ENIAGVGLP----SKTASDVPATQSSRPTGLSATPALD-SITITWNAPEDIGGATEISGY 7934

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
            +IE     G     +   G ++      ++    +  +RI+A   +    P        E
Sbjct: 7935 VIERSISSGFFNPYVDDTGSALTSFVDTSLFSGTDYSYRIAAITLLPSGEPVVGDFSG-E 7993

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
               T    P  P  +++      +T +W  PE   G P+LGY I  R         V   
Sbjct: 7994 VSTTTLDLPDEPTSLQVFADRGQLTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVENT 8053

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            D +   +    L++N +Y  R+      G S+P
Sbjct: 8054 DSDETIYTDSGLNDNTSYSYRVSTITAAGTSDP 8086



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 165/755 (21%), Positives = 285/755 (37%), Gaps = 64/755 (8%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDKPSP-PGKPNILEIDSS 1395
            D    S T+   + T+  +Y  R+   N  G +D     T   KP+  PG P+ L++D +
Sbjct: 6597 DGSDTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDP---ATASAKPATTPGAPDALQLDFA 6653

Query: 1396 S--INICWDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSY 1449
            +  +++ W  P + G   I  Y+VEY  +DT+EWI    +V     T  ++ +L     Y
Sbjct: 6654 NQLVSLEWAVPTDDGGDEIDDYIVEY-SLDTSEWIVFPDNVTPANSTAVTVTDLINGFQY 6712

Query: 1450 RFRAYAVNEVDISDASE--TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI---ELTC- 1503
             FR   VN   I + SE   T    +    +    T +    ++T    ED+    L+  
Sbjct: 6713 FFRISGVNIAGIGEPSEFRATTPATLPSAPRDLEATRDNTSVHLTWNVPEDLGGAPLSAY 6772

Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
            +   +P  + TW + G  L   + +                    K  A  D G    + 
Sbjct: 6773 MVEYLPPGQSTWIKFGDDLPATQTSV--TVDGLTNGDQYQFRITAKNTAITDFGPASDTV 6830

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNI 1621
                   P        I   ++    W V    E      +  YK   ++  ++   Y+ 
Sbjct: 6831 SATPATTPTAPRDLVVIAGNNQATLSWNVP---ESNGGDSITDYKIEIRIAGQDWDVYDD 6887

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
                 T  I I  L    + ++ + A N+   G +S  V  K    P+ P+  V++   +
Sbjct: 6888 GVSTTTQGIVIPNLTNGVTYEFRVTAINSVNPGPASDVVPGKPATIPTPPKKLVVIPGDT 6947

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPD-----NNRWIKVADVDRDVETYCIQKLNEN 1734
            +  VT  W  P ++GG  +T Y ++ +  D     +   + V D+   + T  I  L  +
Sbjct: 6948 KLDVT--WTKPTNNGGSAITSYLVQ-YSTDGTFDASTPSVTVTDLTNLMVT--ISGLEND 7002

Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
                 +V A N VG S    + P++   +L   S          I +  V+++W P ++ 
Sbjct: 7003 VPIHVQVTAINGVGSSG--PAGPVIGVPSLG--SSSPVGLFADAISDTEVFVSWSPPQEL 7058

Query: 1795 GGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEI-GTSLP 1850
            G   +  + +E +   G   +                +   TTY++++ A   + G    
Sbjct: 7059 GDRTLEGFVLERLDANGNVLETFTINDPTKLDFTDTGLLPGTTYKYQVSALLSLEGADTV 7118

Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT--VK 1908
             +     T   TL  P  P +   +   +  V L W+ P ++GGS IT Y I++ T    
Sbjct: 7119 QSDPSSRTSVTTLDAPGAPLSPSATPGNAH-VDLSWSAP-NDGGSLITEYRIQYSTDGTF 7176

Query: 1909 GKSWTKIVTVGGSVH----EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
             ++  +I   G S         +  +    E  FR+ A   +  SLP  S +V    + T
Sbjct: 7177 DETTPEISVFGTSTEPPQTSVDVTGLTNDQEYTFRVIAVTVIDTSLP--SVTVTATPY-T 7233

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME----VGKVD 2020
            VP  P+     R  G      SWG P  D G  +  Y +   D T  ++         V 
Sbjct: 7234 VPDAPSNLTANR--GPGEAKLSWGVPN-DNGRSITQYVVEYTDATDGIFTVANTLTATVS 7290

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
             +     I  L   +++  R+ A N  G   P +S
Sbjct: 7291 ASETSTTITGLGIGNSFTFRVSAENLAGQGPPSDS 7325



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 83/287 (28%), Positives = 119/287 (41%), Gaps = 30/287 (10%)

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKX---XXXXXXXXARIQKLSINTTYQF 1837
            +E V ++W P   NGGS I DY +E   +G  W+              +  L+   +Y F
Sbjct: 1292 DEQVLLSWAPPASNGGSAITDYIIEY-NDGNGWQTFNDGTSTDTTDVAVTGLTNGQSYDF 1350

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGS 1895
            R+ A N  GT       D   I  T TP   P   V+ E+   +  V L W  P +NG +
Sbjct: 1351 RVSAVNTEGTG------DASDIA-TATPAGVPDAPVIDEALGGNGQVYLTWEHPPNNGAA 1403

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTES 1954
             IT+YIIE     G  W ++   G S +    ++N++  +   FR+ A N+ G   P  +
Sbjct: 1404 -ITDYIIEVN--DGNGW-EVFNDGTSTNRFVTVDNLENGETYSFRVKAVNSAGEG-PFST 1458

Query: 1955 QSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
                    AT  S  TAP L     G + V   W  P  DGG+ +  Y I       T  
Sbjct: 1459 PVT-----ATPSSTATAPFLHTLTPGDSEVFVDWDAPNDDGGSTISSYEIQY-STDGTFD 1512

Query: 2014 MEVGKVDVN----TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056
                 V V+      ++ +  L+   TY  R+ A NE G S P   D
Sbjct: 1513 QNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENGSSPPSNLD 1559



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 100/415 (24%), Positives = 159/415 (38%), Gaps = 30/415 (7%)

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKH 1706
            +N   T S  VT      P+ P   +    +S   + + W  PP +     LT Y IE+ 
Sbjct: 2630 NNLTSTPSTPVTATPITTPNAPTN-LDATALSDTEIELTWTAPPTNPQFGTLTGYQIERQ 2688

Query: 1707 -EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
             E + +  I VAD      T+    L+   EY +RV A    G  +A  S P    T   
Sbjct: 2689 AEGEADFTIIVADTQTTATTFNDLGLSSGVEYTYRVSAITTAGIGDA--SSP-ASATTFT 2745

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR 1825
            VP+          + + S+ ++W     NGG+PI  Y + I                 A 
Sbjct: 2746 VPAKPVLNEPV--VGDSSLTVSW-SKPSNGGTPITGYTLSITNLTTGIDLDDVSLSADAT 2802

Query: 1826 IQKLSINTT---YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882
                S+ T    Y F + A N +G+S    S D +T G  L  P+ P N   + S  + V
Sbjct: 2803 DYTASLLTNGNEYSFTLVAINSVGSS---ESSDPVT-GIPLGAPAAPGNLTPT-SGDKQV 2857

Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS----VHEHCIENIKEKDEIIF 1938
             L WT+P+ NG   IT+Y +  +   G     I   G           +  +       F
Sbjct: 2858 DLTWTQPDLNGSGDITSYTVTVRDPNGAIVDTITLTGSQGAPPATSTTVTGLTNGVNYTF 2917

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV-GSNIVMTSWGTPEWDGGAP 1997
             ++A N    + P  + +       T    P AP  +    G   V  +W  P+ +G   
Sbjct: 2918 EVTATNENNSTGPAATTT------ETPLGAPAAPGNLTPTSGDKQVDLTWTQPDLNGSGD 2971

Query: 1998 LLGYNIAIRDVTKTM--WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            +  Y I +RD +  +   + +G  +  T  + +  L+ +  Y   + A NE  L+
Sbjct: 2972 ITLYTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLT 3026



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 109/437 (24%), Positives = 170/437 (38%), Gaps = 43/437 (9%)

Query: 1669 PEGPVIMREISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK-----VADVDR 1721
            P+ P ++      +  V++ W   + DGG  L  Y +E  + +N  + +     +   D 
Sbjct: 4033 PDAPTLLEVTDHGNGFVSLSWTASVFDGGSTLNTYVVEYTDDENGVFDEPPSSVIIGDDE 4092

Query: 1722 DVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
             ++T   +  L+   EY FRV A N  G S    +E  V +T    P             
Sbjct: 4093 TLDTQATVSGLDNGVEYTFRVKATNDNG-SSGYSNE--VTETPARAPDAPTLDSAVRG-- 4147

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEG-------KKWKXXXXXXXXXARIQKLSINT 1833
            +ESV ++W P   +GGS +  Y V+    G                      I  L+   
Sbjct: 4148 DESVTLSWTPGF-DGGSDLTQYTVQYTPTGIFDPENTVSEVFDTEPLPTTVTIDSLTNGV 4206

Query: 1834 TYQFRIYARN-EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
            TY FR++A N E    +  T D      K  T P++P   + +E  +  V L W  P  N
Sbjct: 4207 TYTFRVFATNIEDNGPVSNTLD-----AKPATVPTKPLQ-LNAEFGNLLVILDWQLPADN 4260

Query: 1893 GGSPITNYIIEFK---TVKGKSWTKIVTVGGSVHEHCIENIKEKDEII---FRISAENTV 1946
            GG  I +YIIE++    +   +W       G V+ +    +      +   FR+SAEN V
Sbjct: 4261 GGEEIIDYIIEYRLASQIPEATWQVFDEGVGGVNTNLFVTVTGLTNGLTYEFRVSAENAV 4320

Query: 1947 GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
             V  PT   +V   + AT+   PT  L+   +    +   W  P   GGA + GY I  R
Sbjct: 4321 DVG-PT--SNVATARPATLSDAPTG-LDAEAISDTEIDLEWNAPLLTGGASIDGYQIE-R 4375

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRD--LSENHTYMIRIYARNEIGLSEPLESDEPFKV-IP 2063
                     +   D  +      D  L    +Y  R+ A  + G+ +   + E     +P
Sbjct: 4376 QAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAAITDAGVGDTSSTAEATTFDVP 4435

Query: 2064 GEGSHADEEPGE-QTEV 2079
            G+       PG  Q EV
Sbjct: 4436 GKTEIISLTPGNAQVEV 4452



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 115/467 (24%), Positives = 179/467 (38%), Gaps = 55/467 (11%)

Query: 1635 LKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
            L+     ++ + A +T GTS  S   T      PS P   V  R  +  S+T  W  P D
Sbjct: 6195 LENGEEYEFRVYAISTVGTSLPSDVATGIPATTPSAPLNVVATRGDTEVSLT--WDLPAD 6252

Query: 1693 DGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFS 1750
            DGG  +  Y +E    + N  +    + +   + +  +  L    EY FRV A N +   
Sbjct: 6253 DGGSAIRDYLVEYASAELNLIYTPFVEPEESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG 6312

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
            +   S       A+               D+E V +TW  S+ NGG+ ++ Y++E   +G
Sbjct: 6313 DY--SAVTADSAAVPAGDPSTPVISTVIADDELVNLTWLASDANGGNNLV-YRIETSTDG 6369

Query: 1811 KKWKXXX---XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
                              +  L     Y FRI A  + G+S P       T   T TP +
Sbjct: 6370 FTTLIEDPAPTTSNLVYNVDDLQNGQEYSFRITAITDAGSSDP-------TAPVTATPFA 6422

Query: 1868 QPRNFVVSESTSRS-VTLKWTEPESNGGSPITNYII-----EFKTV-------------- 1907
             P   V+  S   + VTL WT+ ++ GG  I  ++I     EF +               
Sbjct: 6423 LPDAPVLDGSRGNTEVTLTWTQGDT-GGFAIQEFVIEYTADEFTSDTPIVRTNDDDDDDD 6481

Query: 1908 -------KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
                    G S    +TV      H IE +       FRI A+ ++G S    S +V   
Sbjct: 6482 DDDDDDGNGNSSVTSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYSA---SSNVVTF 6538

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK---TMWMEVG 2017
              AT+P  PT PL  +  G+ +V  ++  P  +GG  +  + I  R  +    T +    
Sbjct: 6539 TPATIPGAPT-PLSAQF-GNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFA 6596

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064
                 +    + DL+    Y  R+ A NE+G S+P  +       PG
Sbjct: 6597 DGSDTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDPATASAKPATTPG 6643



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 101/421 (23%), Positives = 157/421 (37%), Gaps = 30/421 (7%)

Query: 1643 YTIEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
            YT E S T   +S       T   Y  P+ P    +      + V + W  P  +G  ++
Sbjct: 3113 YTFEVSATNENNSTGPAATATATPYGPPAAPGN--LTPTPGDKQVDLTWTQPDLNGSGDI 3170

Query: 1699 TKYAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
            T Y I   +P     + I + D +    +Y +  L  +  Y F V A N    + +  + 
Sbjct: 3171 TLYTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLTSSAATT 3230

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815
                 TA    +            +    ++W  ++ N    I  Y + I   +G     
Sbjct: 3231 -----TATPRGAPLQVTGLEATPGDRQASLSWNEADDNNSGDISYYTITITGSDGVPVDP 3285

Query: 1816 XXXXX-XXXARIQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                       I  L+    Y+F I A NE G TS P         G    PP+      
Sbjct: 3286 VQVTAPADNTVIPGLTSGVEYEFTITATNEHGLTSTPSAPATATPFG----PPNAVTGLG 3341

Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933
             +    + V L+WTEP  N G  I +Y I      G +  + +T+     E  I+ +   
Sbjct: 3342 ATPG-DKQVDLEWTEPVPNAGGEIASYTITVTDPNG-NVVQTITINAPADEANIDGLNNG 3399

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
             E  F I+A N  GV   T   +      ATVP PP   L+    G+  V  SW TP++D
Sbjct: 3400 VEYTFTITATNVNGV---TGDAATITAIPATVPLPPV--LDSADRGNQSVTLSW-TPQFD 3453

Query: 1994 GGAPLLGYNI--AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
             G+ +  Y I  +  +   T  + +G  +       I  L+   TY  ++ A N  G S+
Sbjct: 3454 QGSTITQYTIQYSSDNFQTTGTVVIGDDEALATSTTISGLTNGLTYQFQVIASNAFGPSD 3513

Query: 2052 P 2052
            P
Sbjct: 3514 P 3514



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 138/691 (19%), Positives = 249/691 (36%), Gaps = 56/691 (8%)

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTN 1446
            +E     + + W  P N G   I  YV+E    D   ++     ++I  T   +  L+  
Sbjct: 1672 VERGDEQVLLTWSAPNNHG-FPITDYVIEVDYGDGNGFVVYNDGQSIDTTDVPVTGLENG 1730

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL---TC 1503
              ++FR YAVN   + +A+ + E    ++ T  ++P  + P+       +  IE+   T 
Sbjct: 1731 VLHKFRVYAVNA--LGNATPSNE----VEATPARAP--DAPVITELNAGDGQIEVIWSTP 1782

Query: 1504 IFGG--VPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGE 1558
              GG  + + ++ W  +         T                      ++ IA ND  E
Sbjct: 1783 DDGGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTYYFRVIAINDVDE 1842

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV---TAVIEGIPPPEVIWYKNGNKLEN 1615
             + S    ++    +T+  + +     VGD  L    +A  +G  P         +    
Sbjct: 1843 SDPS---DVESAIPVTVPAKPVLNTPVVGDSSLTVSWSAPNDGGSPLTGYTLSITDVTGG 1899

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
            +   +++           EL   ++  +T+ A N  G+S     +      +  +   + 
Sbjct: 1900 NTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDPSDAVTGIPIGAPGQIDDLG 1959

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV----DRDVETYCIQKL 1731
             E   + V + W  P  +G  ++T Y IE  +        +       +    +  +  L
Sbjct: 1960 AESGDKQVDLTWTQPDLNGSGDITSYTIEVRDSSGTLVDTIVITGTGGNPPATSTTVTGL 2019

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
              N  Y F + A N    +    S+P+   T L  P+            ++ V +TW   
Sbjct: 2020 TNNETYSFTITATNENNLTST-PSDPVT-STPLGAPAAPGNLTPTPG--DKQVDLTWTQP 2075

Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-----IQKLSINTTYQFRIYARNEIG 1846
            + NG   II Y V ++                A      +  L+ +  Y F + A NE  
Sbjct: 2076 DLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENN 2135

Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
                 TS    T    L  P Q  +   +ES  + V L WT+P+ NG   IT+Y IE + 
Sbjct: 2136 L----TSSAATTTSTPLGAPGQI-DTPTAESGDKQVDLTWTQPDLNGSGDITSYTIEVRD 2190

Query: 1907 VKGKSWTKIVTVGGS----VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
              G     IV  G         + +  +   +   F I+A N   ++  T S  V     
Sbjct: 2191 SSGTLVDTIVITGTGGNPPATSYTVPGLDNGETYSFTITATNENNLT-STPSDPVT---- 2245

Query: 1963 ATVPSPPTAPLEIRMV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKV 2019
            +T    P AP  +    G   V  +W  P+ +    +  Y I +RD +  +   + +G  
Sbjct: 2246 STPLGAPAAPGNLAPTPGDKQVDLTWTQPDLNNSGDITLYTITVRDPSGAVVQTIVIGDD 2305

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            +    +  +  L+ +  Y   + A NE  L+
Sbjct: 2306 EALATETTVTGLTNSVNYTFEVTATNENNLT 2336



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 92/365 (25%), Positives = 139/365 (38%), Gaps = 30/365 (8%)

Query: 1643 YTIEASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
            Y I A   AGT  SS   +   ++ P KP   +    +    + I W  P D+GG  +T 
Sbjct: 6106 YRISAITGAGTGSSSQPASDTTFNVPDKPT--ITEVNVGNNELEIVWTAPTDNGGSPVTS 6163

Query: 1701 YAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            Y +E     +N W    V   D  ++   I  L    EY FRV A + VG      S P 
Sbjct: 6164 YTVEYKLTTDNTWQLSPVPPADGALDVTVI-GLENGEEYEFRVYAISTVG-----TSLPS 6217

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-----KKW 1813
             + T +   +            +  V +TW     +GGS I DY VE            +
Sbjct: 6218 DVATGIPATTPSAPLNVVATRGDTEVSLTWDLPADDGGSAIRDYLVEYASAELNLIYTPF 6277

Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873
                        +  L+    Y FR+ A NEI     Y++   +T      P   P   V
Sbjct: 6278 VEPEESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG-DYSA---VTADSAAVPAGDPSTPV 6333

Query: 1874 VSE--STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
            +S   +    V L W   ++NGG+ +  Y IE  T    +  +      S   + +++++
Sbjct: 6334 ISTVIADDELVNLTWLASDANGGNNLV-YRIETSTDGFTTLIEDPAPTTSNLVYNVDDLQ 6392

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
               E  FRI+A    G S PT   +      AT  + P AP+     G+  V  +W   +
Sbjct: 6393 NGQEYSFRITAITDAGSSDPTAPVT------ATPFALPDAPVLDGSRGNTEVTLTWTQGD 6446

Query: 1992 WDGGA 1996
              G A
Sbjct: 6447 TGGFA 6451



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 106/461 (22%), Positives = 170/461 (36%), Gaps = 55/461 (11%)

Query: 1609 NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK 1665
            NGN LE     + T  +   T ++     K   S+  ++E ++T  +  S   ++   D 
Sbjct: 7074 NGNVLETFTINDPTKLDFTDTGLLPGTTYKYQVSALLSLEGADTVQSDPSSRTSVTTLDA 7133

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP----DNNRWIKV--ADV 1719
            P  P  P          V + W  P +DGG  +T+Y I+        +    I V     
Sbjct: 7134 PGAPLSPSATP--GNAHVDLSWSAP-NDGGSLITEYRIQYSTDGTFDETTPEISVFGTST 7190

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779
            +    +  +  L  + EY FRVIA   +  S    +      T  D PS           
Sbjct: 7191 EPPQTSVDVTGLTNDQEYTFRVIAVTVIDTSLPSVTVTATPYTVPDAPSNLTANRGPG-- 7248

Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVE-------IKQEGKKWKXXXXXXXXXARIQKLSIN 1832
                  ++W     NG S I  Y VE       I                   I  L I 
Sbjct: 7249 ---EAKLSWGVPNDNGRS-ITQYVVEYTDATDGIFTVANTLTATVSASETSTTITGLGIG 7304

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
             ++ FR+ A N  G   P  S     I    T P  P     +      + + W  P S+
Sbjct: 7305 NSFTFRVSAENLAGQGPPSDS----AIATPATAPDAPTGLSATRGDPDVLAI-WFNPPSD 7359

Query: 1893 GGSPITNYIIEFKT---------VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
            GGSPI++Y++E+ T             S T ++T   SV    +++++      FR+ A 
Sbjct: 7360 GGSPISHYVLEYTTSPFFVPPEIADFTSKTNVITESTSVE---LDDLENGLYYYFRVRAI 7416

Query: 1944 NTVGVSLPTE---------SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS---WGTPE 1991
             TVG S+PT+         S S      A +P       +  ++G+     +   W TP 
Sbjct: 7417 TTVGSSIPTDPVCLVNGGGSNSAANAGGACIPMFDRPVFQDTIIGTPFDAAAELRWNTPA 7476

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
             D G+P+ GY +  R V     + + + + N + +   DL+
Sbjct: 7477 ADNGSPITGYQVQ-RQVVSGTSVVLEQFNQNQIIYGFDDLT 7516



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 57/233 (24%), Positives = 96/233 (41%), Gaps = 15/233 (6%)

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            I+ L+    Y FRI+A+  IG    Y++   +      T P  P   + ++  +  VTL 
Sbjct: 6508 IEGLANGVAYDFRIFAKTSIG----YSASSNVVTFTPATIPGAPTP-LSAQFGNALVTLT 6562

Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH---CIENIKEKDEIIFRISA 1942
            ++ P  NGG  + +++I+++       T   T            + ++   +   FR+ A
Sbjct: 6563 FSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTSTTVTVTDLTNGEVYDFRVIA 6622

Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002
             N VG S P  + +    K AT P  P A L++    + +V   W  P  DGG  +  Y 
Sbjct: 6623 VNEVGQSDPATASA----KPATTPGAPDA-LQLDF-ANQLVSLEWAVPTDDGGDEIDDYI 6676

Query: 2003 IAIR-DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            +    D ++ +         N+    + DL     Y  RI   N  G+ EP E
Sbjct: 6677 VEYSLDTSEWIVFPDNVTPANSTAVTVTDLINGFQYFFRISGVNIAGIGEPSE 6729



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 49/178 (27%), Positives = 77/178 (43%), Gaps = 9/178 (5%)

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXX---XXXXARIQKLSINTTYQ 1836
            +E V ++W     +GG+ I  Y V+ +  G   W               +  L    TY+
Sbjct: 342  DEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTTSLPVTGLINGVTYE 401

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            F++ A N +G S P +     T   ++T P QP     S + ++ V L WT P S+GGS 
Sbjct: 402  FQVLAHNSVGNSNP-SGAANATPEDSVTVPGQPTELTAS-AGNQQVLLSWTAP-SDGGSA 458

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
            IT+YI+E     G  W        +     +  +  + E  FR+SA N  G    +E+
Sbjct: 459  ITDYIVEVD--DGDGWETFADGTSTDTTATVTGLTNEQEHTFRVSAVNDEGTGNTSET 514



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 58/194 (29%), Positives = 82/194 (42%), Gaps = 14/194 (7%)

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKI 1915
            IT    L  P  P N + +ES    V L W  P SNGGS IT+YIIE+    G  W T  
Sbjct: 1271 ITYTAELGVPGAPTN-LTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFN 1327

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
                    +  +  +       FR+SA NT G     ++  +     A VP  P   ++ 
Sbjct: 1328 DGTSTDTTDVAVTGLTNGQSYDFRVSAVNTEGTG---DASDIATATPAGVPDAPV--IDE 1382

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF-NIRDLSEN 2034
             + G+  V  +W  P  + GA +  Y I + D     W EV     +T +F  + +L   
Sbjct: 1383 ALGGNGQVYLTWEHPP-NNGAAITDYIIEVND--GNGW-EVFNDGTSTNRFVTVDNLENG 1438

Query: 2035 HTYMIRIYARNEIG 2048
             TY  R+ A N  G
Sbjct: 1439 ETYSFRVKAVNSAG 1452



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 49/195 (25%), Positives = 82/195 (42%), Gaps = 7/195 (3%)

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGG 1920
            T + P QP N + + +    VT+ WT P S+GG+ I  Y ++++     +WT    T  G
Sbjct: 326  TASVPGQPLN-ISATAGDEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDG 384

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980
            +     +  +       F++ A N+VG S P+ + +   E   TVP  PT        G+
Sbjct: 385  TTTSLPVTGLINGVTYEFQVLAHNSVGNSNPSGAANATPEDSVTVPGQPTE--LTASAGN 442

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
              V+ SW  P  DGG+ +  Y + + D     W              +  L+    +  R
Sbjct: 443  QQVLLSWTAPS-DGGSAITDYIVEVDD--GDGWETFADGTSTDTTATVTGLTNEQEHTFR 499

Query: 2041 IYARNEIGLSEPLES 2055
            + A N+ G     E+
Sbjct: 500  VSAVNDEGTGNTSET 514



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 92/428 (21%), Positives = 152/428 (35%), Gaps = 43/428 (10%)

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREISRES-VTIEWKPPLDDGGLELTK 1700
            YT E + T   +S        + P   P  P  +   S +  V + W  P  +G  ++T 
Sbjct: 2915 YTFEVTATNENNSTGPAATTTETPLGAPAAPGNLTPTSGDKQVDLTWTQPDLNGSGDITL 2974

Query: 1701 YAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            Y I   +P     + I + D +    +Y +  L  +  Y F V A N    + +  +   
Sbjct: 2975 YTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLTSSAATT-- 3032

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818
               TA    +            ++ V + W P+++N    I  Y VE+            
Sbjct: 3033 ---TATPRGAPLQVTGLEATPGDKQVSLEWDPADENNSGAITSYTVEVYDSSNTLVDTIT 3089

Query: 1819 XX-------XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
                          +  L    TY F + A NE  ++ P  +      G    PP+ P N
Sbjct: 3090 VTGTGGNPPATSTTVTGLDNGETYTFEVSATNENNSTGPAATATATPYG----PPAAPGN 3145

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS---VHEHCIE 1928
               +    + V L WT+P+ NG   IT Y I  +   G +  + + +G        + + 
Sbjct: 3146 LTPTPG-DKQVDLTWTQPDLNGSGDITLYTITVRDPSG-AVVQTIVIGDDEALTTSYLVT 3203

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV----GSNIVM 1984
             +       F ++A N   +   T S +       T  +P  APL++  +    G     
Sbjct: 3204 GLTNSVNYTFEVTATNENNL---TSSAA------TTTATPRGAPLQVTGLEATPGDRQAS 3254

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN--IRDLSENHTYMIRIY 2042
             SW   + +    +  Y I I   T +  + V  V V     N  I  L+    Y   I 
Sbjct: 3255 LSWNEADDNNSGDISYYTITI---TGSDGVPVDPVQVTAPADNTVIPGLTSGVEYEFTIT 3311

Query: 2043 ARNEIGLS 2050
            A NE GL+
Sbjct: 3312 ATNEHGLT 3319



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 7/170 (4%)

Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMF 1739
            E VT+ W  P  DGG  +  Y ++        W    +  D    +  +  L     Y F
Sbjct: 343  EQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTTSLPVTGLINGVTYEF 402

Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
            +V+A N VG S    +     + ++ VP             N+ V ++W  +  +GGS I
Sbjct: 403  QVLAHNSVGNSNPSGAANATPEDSVTVPGQPTELTASA--GNQQVLLSW-TAPSDGGSAI 459

Query: 1800 IDYKVEIKQEGKKWKXXX--XXXXXXARIQKLSINTTYQFRIYARNEIGT 1847
             DY VE+  +G  W+           A +  L+    + FR+ A N+ GT
Sbjct: 460  TDYIVEV-DDGDGWETFADGTSTDTTATVTGLTNEQEHTFRVSAVNDEGT 508



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 104/468 (22%), Positives = 170/468 (36%), Gaps = 49/468 (10%)

Query: 1638 SHSSKYTIEAS----NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
            ++S  YT E +    N   +S+   T      P + + P    E   + V + W  P  +
Sbjct: 2119 TNSVNYTFEVTATNENNLTSSAATTTSTPLGAPGQIDTPTA--ESGDKQVDLTWTQPDLN 2176

Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADV----DRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
            G  ++T Y IE  +        +       +    +Y +  L+    Y F + A N    
Sbjct: 2177 GSGDITSYTIEVRDSSGTLVDTIVITGTGGNPPATSYTVPGLDNGETYSFTITATNENNL 2236

Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809
            +    S+P+   T L  P+            ++ V +TW   + N    I  Y + ++  
Sbjct: 2237 TST-PSDPVT-STPLGAPAAPGNLAPTPG--DKQVDLTWTQPDLNNSGDITLYTITVRDP 2292

Query: 1810 GKKWKXXXXXXXXXA-----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
                          A      +  L+ +  Y F + A NE       TS    T   T T
Sbjct: 2293 SGAVVQTIVIGDDEALATETTVTGLTNSVNYTFEVTATNENNL----TSSAATT---TAT 2345

Query: 1865 PPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS- 1921
            P   P      E+T   R V+L+W   + N    IT+Y +E       +    +TV G+ 
Sbjct: 2346 PRGAPEQVTGLEATPGDRQVSLEWDPADENNSGAITSYTVEVYD-SSNTLVDTITVTGTG 2404

Query: 1922 ----VHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976
                     +  +   +   F I+A N  G+ S+P+      L   AT   PP    +++
Sbjct: 2405 GNPPATSTTVPGLTSGETYSFTITATNGHGLTSIPS------LPVTATPFGPPNPVTDLQ 2458

Query: 1977 MV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKVDVNTLKFNIRDLSE 2033
             + G   V   W  P  + G  +  Y I +RD +  +   + +G  +      NI  L+ 
Sbjct: 2459 AISGDKQVDLIWTQPVPNAGGAIETYTITVRDPSGNVVQTIVIGDDEPLATSVNIDGLNN 2518

Query: 2034 NHTYMIRIYARNEIGL-SEPLESDE-PFKVIPG--EGSHADEEPGEQT 2077
               Y   I A N   L S  + + E PF   PG  +   AD   GE T
Sbjct: 2519 GVEYTFEIIATNSNNLDSSAVSTTEIPFGP-PGVIDTPTADAGDGEVT 2565



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 15/184 (8%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVI--WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH--- 1639
            K+  +W+      G P    +  W  NG    N      T K   S +    +K S+   
Sbjct: 8595 KIVIDWVAPTSNGGTPIVNYLIQWSDNGGSKWN------TLKRDASAVTSATVKSSNIVL 8648

Query: 1640 SSKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGP-VIMREISRESVTIEWKPPLDDGGL 1696
             ++Y I   A NT G      ++K     + P  P  ++ +     V + W  PL DGG 
Sbjct: 8649 GTEYQIRVYAENTIGPGPAS-SVKSVTPTTIPTAPRSLVTDPQDGQVVLSWSKPLSDGGS 8707

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
             +T Y +   E  + +++  AD      T  +  L  +  Y FRV+A N VG S A   +
Sbjct: 8708 AITDYLVRYSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRVVAVNSVGNSPASTGK 8767

Query: 1757 PIVI 1760
             + +
Sbjct: 8768 SVAV 8771



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 11/137 (8%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN---ILEIDSSSINIC 1400
            S+TI  + N     +++  +N      +  NV   +  S P  P    +  I    ++I 
Sbjct: 5285 SITIDDLTNGVTYEFRVFAKNTVPGQSLPSNVLSAEPSSAPSVPRDLRVTNIGDEFVSIS 5344

Query: 1401 WDEPENTGNSTIIYYVVEYQE-----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
            W  P + G   I+ Y V+Y +     I T E + V  +  T  ++ +L+    Y+FR  A
Sbjct: 5345 WLAPADNGGDDIVGYTVQYSDDNFTTISTQEIVPVSGVLPTDATVSSLENGVDYQFRVIA 5404

Query: 1456 VNEVD---ISDASETTE 1469
             NE D   I D+S+ ++
Sbjct: 5405 HNEDDDPQIPDSSDPSD 5421



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 13/156 (8%)

Query: 1346 TIKKVENTDAGIYKLRLEN--NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
            T   +EN     Y++   N    G A    + T LD P PP         ++ + + WD 
Sbjct: 8337 TDNSLENGQTYYYRISAINAKGTGTASDVASATPLDVPGPPRNLQTTP-GNAQVTLAWDI 8395

Query: 1404 PE-------NTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            P        + G S I  YVV Y  IDT  W   + + IT+    +  L    +Y+FR +
Sbjct: 8396 PSTDGGITADNGGSIITGYVVHYA-IDTNFWKTFNEEPITERTVDVTGLTNGQNYKFRVF 8454

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
            AVNEV     S  +    V    +    T+  P +N
Sbjct: 8455 AVNEVGFLHPSLVSSEIPVTVPERPWGLTITAPSQN 8490



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 9/91 (9%)

Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTE------WISVKNITK 1435
            P KP I   D  ++ +++ W EP N G + I  Y+V+Y +  T +       ++  ++T+
Sbjct: 5837 PDKPEITSADRGNTQVDLSWTEPANNG-AAITAYLVQYSDDGTFDNTTPSVTLATADLTE 5895

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
              T+I  L+    Y FR  A+N V  SD S+
Sbjct: 5896 LSTTIDGLENGEEYSFRIIAINSVGQSDPSD 5926



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            +T     + PS P N + +   +  V+L WT P  NGGS IT+Y++E+ +  G  W    
Sbjct: 983  VTYSFEASAPSAPTNLIATAGNT-DVSLSWTAP-FNGGSDITDYVVEYSS--GSGWNTFA 1038

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
                +     +  +    E  FR+SA N  G
Sbjct: 1039 DGTSTDTTATVTGLTNDQEYSFRVSAVNAEG 1069



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 10/114 (8%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-----IDTTEWISVKNITK 1435
            P PP    + +  ++ +++ W  P + G   ++ Y V+Y +     I T E I V  +  
Sbjct: 3925 PLPPRDLQVTDSGNAFVSLSWLTPLDDGGDDLVGYTVQYSDDNFATISTQEIIPVDGVLP 3984

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNE-----VDISDASETTEYYKVIKETKIQSPTV 1484
            T  +I  L   S Y+FR  A NE      D  D+S+ +        T   +PT+
Sbjct: 3985 TTATISGLDNGSEYKFRVIAHNEDDGDNDDTDDSSDPSNTVSATPSTVPDAPTL 4038



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 5/133 (3%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSS 1396
            D  + SL +  + N     +++   N+ G+++     N T  D  + PG+P  L   + +
Sbjct: 383  DGTTTSLPVTGLINGVTYEFQVLAHNSVGNSNPSGAANATPEDSVTVPGQPTELTASAGN 442

Query: 1397 --INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
              + + W  P + G S I  Y+VE  + D  E  +    T T  ++  L     + FR  
Sbjct: 443  QQVLLSWTAPSD-GGSAITDYIVEVDDGDGWETFADGTSTDTTATVTGLTNEQEHTFRVS 501

Query: 1455 AVNEVDISDASET 1467
            AVN+    + SET
Sbjct: 502  AVNDEGTGNTSET 514



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 7/132 (5%)

Query: 1340 SKSASLTIKKVENTDAGIYKLRL--ENNCGH--ADVEMNVTILDKPSPPGKPNILEIDSS 1395
            S   S T+K         Y++R+  EN  G   A    +VT    P+ P +  + +    
Sbjct: 8634 SAVTSATVKSSNIVLGTEYQIRVYAENTIGPGPASSVKSVTPTTIPTAP-RSLVTDPQDG 8692

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453
             + + W +P + G S I  Y+V Y E  + ++++  +   T T  ++  L  + +Y FR 
Sbjct: 8693 QVVLSWSKPLSDGGSAITDYLVRYSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRV 8752

Query: 1454 YAVNEVDISDAS 1465
             AVN V  S AS
Sbjct: 8753 VAVNSVGNSPAS 8764



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 1384 PGKPNILEIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT--- 1438
            PG P  L  +S    + + W  P + G S I  Y++EY   D   W +  + T T T   
Sbjct: 1280 PGAPTNLTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFNDGTSTDTTDV 1337

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            ++  L    SY FR  AVN     DAS+
Sbjct: 1338 AVTGLTNGQSYDFRVSAVNTEGTGDASD 1365



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 15/125 (12%)

Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT----Q 1437
            P KP I E++  ++ + I W  P + G S +  Y VEY+      W  +  +        
Sbjct: 6131 PDKPTITEVNVGNNELEIVWTAPTDNGGSPVTSYTVEYKLTTDNTW-QLSPVPPADGALD 6189

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
             ++  L+    Y FR YA++ V  S  S+          T I + T   PL  + T  + 
Sbjct: 6190 VTVIGLENGEEYEFRVYAISTVGTSLPSDVA--------TGIPATTPSAPLNVVATRGDT 6241

Query: 1498 DIELT 1502
            ++ LT
Sbjct: 6242 EVSLT 6246



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 11/133 (8%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWD 1402
            SL I ++ N    ++++   N+ G  D+   VT     +P    N++    +  + + W+
Sbjct: 3680 SLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTATPATAPSAPQNLVATPQTGQVLLVWE 3739

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----------KTQTSIQNLKTNSSYRFR 1452
            +P + G +TI  Y V++   +T +  + +++T           T T++  L    +Y F 
Sbjct: 3740 KPSSNGGATITSYTVKWTPGETFDPNNFESVTITSVDGVAPPVTTTTVTGLTNGQTYTFV 3799

Query: 1453 AYAVNEVDISDAS 1465
              A N  D   AS
Sbjct: 3800 VTATNSADEGPAS 3812



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 6/125 (4%)

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSIN 1398
            S +  +T+  +EN +   ++++  N+ G       VT     +      + L    S + 
Sbjct: 1425 STNRFVTVDNLENGETYSFRVKAVNSAGEGPFSTPVTATPSSTATAPFLHTLTPGDSEVF 1484

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDT----TEWISVK-NITKTQTSIQNLKTNSSYRFRA 1453
            + WD P + G STI  Y ++Y    T    T  ++V  N   T+ ++  L    +Y FR 
Sbjct: 1485 VDWDAPNDDGGSTISSYEIQYSTDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRV 1544

Query: 1454 YAVNE 1458
             A+NE
Sbjct: 1545 IAINE 1549



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 5/129 (3%)

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWDE 1403
            +T+  +EN +   +++   +  G +      T +   +P    N++     + +++ WD 
Sbjct: 6190 VTVIGLENGEEYEFRVYAISTVGTSLPSDVATGIPATTPSAPLNVVATRGDTEVSLTWDL 6249

Query: 1404 PENTGNSTIIYYVVEYQEIDT----TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
            P + G S I  Y+VEY   +     T ++  +  T   T++  L     Y FR  AVNE+
Sbjct: 6250 PADDGGSAIRDYLVEYASAELNLIYTPFVEPEESTDRFTTVTGLTNGVEYTFRVQAVNEI 6309

Query: 1460 DISDASETT 1468
               D S  T
Sbjct: 6310 AAGDYSAVT 6318



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            +T     T PS P N   +    + V+L WT P S+GGS IT+YIIE     G  W    
Sbjct: 696  VTYSFVATAPSAPTNLSATAGNEQ-VSLSWTAP-SDGGSAITDYIIEVD--DGDGWETFA 751

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
                +     +  +    E  FR+SA N  G
Sbjct: 752  DGTSTDTTATVTGLTNGQEHTFRVSAVNGEG 782



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%)

Query: 1382 SPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITK 1435
            S PG P    LE +   I I W  P + G + I+ Y++++ +   ++W ++K     +T 
Sbjct: 8579 SVPGAPRNLTLEAEGKKIVIDWVAPTSNGGTPIVNYLIQWSDNGGSKWNTLKRDASAVTS 8638

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
                  N+   + Y+ R YA N +    AS
Sbjct: 8639 ATVKSSNIVLGTEYQIRVYAENTIGPGPAS 8668



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 13/126 (10%)

Query: 1353 TDAGIYKLRL--ENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWDEPENTG 1408
            T+   Y+ R+  EN+ G ++   NV      + P KP  +  E     +++ W EPE +G
Sbjct: 5601 TNGQTYEFRVIAENSVGESEAS-NVLQAKPATTPSKPLQVGAEFGDRQVSLTWLEPEISG 5659

Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNI--------TKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
               I  Y++E++    T   S +          T     I  L    +Y FR  A N+V 
Sbjct: 5660 GEDIFDYILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAENDVG 5719

Query: 1461 ISDASE 1466
            + D S+
Sbjct: 5720 VGDVSD 5725



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 9/136 (6%)

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNC----GHADVEMNVTILDKPSPPGKPNILEID 1393
            + +   S+T+  + N D   +++  +N      G A   ++ T    P+ P +  ++   
Sbjct: 6791 LPATQTSVTVDGLTNGDQYQFRITAKNTAITDFGPASDTVSATPATTPTAP-RDLVVIAG 6849

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYR 1450
            ++   + W+ PE+ G  +I  Y +E + I   +W    +   T T    I NL    +Y 
Sbjct: 6850 NNQATLSWNVPESNGGDSITDYKIEIR-IAGQDWDVYDDGVSTTTQGIVIPNLTNGVTYE 6908

Query: 1451 FRAYAVNEVDISDASE 1466
            FR  A+N V+   AS+
Sbjct: 6909 FRVTAINSVNPGPASD 6924



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 9/107 (8%)

Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY------- 1419
            G A      T  + P  P   ++   D     I W++P N G S II Y+VEY       
Sbjct: 3809 GPASNPATTTPANPPDAPVLVSVTSDDDQESTIVWNQPAN-GGSPIIDYLVEYTSTGAFN 3867

Query: 1420 -QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             Q+ ++    + +N     T+I  L     Y FR  A N VD  D S
Sbjct: 3868 PQDTESVVITAPQNNDPITTTIDGLDNGVEYSFRVTARNLVDSGDPS 3914



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 31/137 (22%), Positives = 62/137 (45%), Gaps = 8/137 (5%)

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--E 1391
            T  ++ + + S TI+ + N  A  +++  + + G++    NV      + PG P  L  +
Sbjct: 6495 TSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYS-ASSNVVTFTPATIPGAPTPLSAQ 6553

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-----TKTQTSIQNLKTN 1446
              ++ + + +  P + G  ++  +V++Y+    +E            T T  ++ +L   
Sbjct: 6554 FGNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTSTTVTVTDLTNG 6613

Query: 1447 SSYRFRAYAVNEVDISD 1463
              Y FR  AVNEV  SD
Sbjct: 6614 EVYDFRVIAVNEVGQSD 6630



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 5/89 (5%)

Query: 1382 SPPGKP-NI-LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---TKT 1436
            S PG+P NI        + + W  P + G + I YY V+Y+      W    N    T T
Sbjct: 328  SVPGQPLNISATAGDEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTT 387

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
               +  L    +Y F+  A N V  S+ S
Sbjct: 388  SLPVTGLINGVTYEFQVLAHNSVGNSNPS 416



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 80/416 (19%), Positives = 144/416 (34%), Gaps = 35/416 (8%)

Query: 1648 SNTAGTSSVEVTLKVYD-KPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
            S+   +S+  + +  Y  + S P  P  ++       V++ W  P + GG ++T Y +E 
Sbjct: 970  SHDGDSSAAPLLVVTYSFEASAPSAPTNLIATAGNTDVSLSWTAPFN-GGSDITDYVVEY 1028

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESEPI-VIK 1761
                 + W   AD      T  +  L  + EY FRV A N  G    S    + PI  + 
Sbjct: 1029 SS--GSGWNTFADGTSTDTTATVTGLTNDQEYSFRVSAVNAEGTGPVSNIATATPIGALT 1086

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821
              + +            +D +         + +GG   + Y +++  +            
Sbjct: 1087 ITIQISQSSDDAEQIRTVDEDD-------DDDDGGGGGVSYSMDLDDDDLDLDEDRFVGL 1139

Query: 1822 XXARI---QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                +      +I   Y       N+ G+S      + +    T T  S   +   S S 
Sbjct: 1140 RFNNVGIPNGATITGAYVEFTSQDNDSGSSSVTIYGEDVDNASTFTTDSTNISSRTSTSA 1199

Query: 1879 SRSVTLK-WTEPESNGGSPITNYI-IEFKTVKGKSWTKIVTVGGSVHEHCIENI-KEKDE 1935
            + S ++  W+E E +  +   + + I  + V    W     V G+      E++  + D 
Sbjct: 1200 TVSWSISDWSENEISSDTQTPSLVSIVQEIVNRGGW-----VSGNSLALIFEDVNSDNDR 1254

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
                  A+++    L      +       VP  PT  L     G   V+ SW  P  +GG
Sbjct: 1255 DALSYDADSSEAPRL-----IITYTAELGVPGAPT-NLTAES-GDEQVLLSWAPPASNGG 1307

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            + +  Y I   D         G    +T    +  L+   +Y  R+ A N  G  +
Sbjct: 1308 SAITDYIIEYNDGNGWQTFNDG-TSTDTTDVAVTGLTNGQSYDFRVSAVNTEGTGD 1362



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 8/128 (6%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNV---TILDKPSPPGKPNILEIDSSSINIC 1400
            S T+  + N D   +++ + +N        NV   T    PS P  P   E   + + + 
Sbjct: 3585 SYTVTGLTNGDTYYFRI-ISSNVIDDSAPSNVLSQTPATTPSEPLNP-AAEPGPNQVEVS 3642

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNE 1458
            W  P + G + I YYVV Y   D   W   +       S  I  L   + Y F  +A N+
Sbjct: 3643 WTLPASDGGAEIEYYVVRY-STDGGSWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHND 3701

Query: 1459 VDISDASE 1466
            V   D S+
Sbjct: 3702 VGDGDISD 3709



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 14/171 (8%)

Query: 1339 DSKSASLTIKKVENTDAGI-YKLRLE--NNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395
            D +S   T   V   + G+ +K R+   N  G+A     V      +P   P I E+++ 
Sbjct: 1713 DGQSIDTTDVPVTGLENGVLHKFRVYAVNALGNATPSNEVEATPARAPDA-PVITELNAG 1771

Query: 1396 S--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----KTQTSIQNLKTNSSY 1449
               I + W  P++ G S I  Y +E+   D +  +    ++     T  ++  L    +Y
Sbjct: 1772 DGQIEVIWSTPDDGGES-IDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTY 1830

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETK--IQSPTV-EKPLKNITTEPNE 1497
             FR  A+N+VD SD S+      V    K  + +P V +  L    + PN+
Sbjct: 1831 YFRVIAINDVDESDPSDVESAIPVTVPAKPVLNTPVVGDSSLTVSWSAPND 1881



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 8/157 (5%)

Query: 1342 SASLTIKKVENTDAGIYKLRL--ENNCGHADVE-MNVTILDKPSPPGKPNILEIDSSSIN 1398
            + S T+  + N +   + +    ENN      + +  T L  P+ PG       D   ++
Sbjct: 2011 ATSTTVTGLTNNETYSFTITATNENNLTSTPSDPVTSTPLGAPAAPGNLTPTPGDKQ-VD 2069

Query: 1399 ICWDEPENTGNSTIIYYVVEYQE----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            + W +P+  G+  II Y V  ++    +  T  I       T   +  L  + +Y F   
Sbjct: 2070 LTWTQPDLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVT 2129

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            A NE +++ ++ TT    +    +I +PT E   K +
Sbjct: 2130 ATNENNLTSSAATTTSTPLGAPGQIDTPTAESGDKQV 2166



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 3/81 (3%)

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWISVKNITKTQTSIQNLKTNSS 1448
            I  + I++ W+ P  TG ++I  Y +E Q   E D T  ++      T  S   L   +S
Sbjct: 4348 ISDTEIDLEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTS 4407

Query: 1449 YRFRAYAVNEVDISDASETTE 1469
            Y +R  A+ +  + D S T E
Sbjct: 4408 YTYRVAAITDAGVGDTSSTAE 4428



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 3/85 (3%)

Query: 1375 VTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
            VT   + S P  P   I    ++ +++ W  P N G S I  YVVEY         +   
Sbjct: 983  VTYSFEASAPSAPTNLIATAGNTDVSLSWTAPFN-GGSDITDYVVEYSSGSGWNTFADGT 1041

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVN 1457
             T T  ++  L  +  Y FR  AVN
Sbjct: 1042 STDTTATVTGLTNDQEYSFRVSAVN 1066



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 14/141 (9%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEID--SS 1395
            +S +  +T+  + N    +++    N  G  D   +V + + P+   G P  L     ++
Sbjct: 4587 ESTTPEITVTGLNNGQEYLFRAVAVNGVGPGDE--SVPVAETPAALSGNPTDLVATRGNT 4644

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEW---ISVKNITK------TQTSIQNLKTN 1446
             +++ W  P  TG   +  Y+VEY +    ++    S + +T       T T I  L+  
Sbjct: 4645 QVSLTWAAPAVTGGVPVTSYIVEYTDDANGDFGANPSSQTVTSETLPVPTNTIINGLQNG 4704

Query: 1447 SSYRFRAYAVNEVDISDASET 1467
             +Y FR  AVN    S  S T
Sbjct: 4705 VTYTFRVIAVNTAGPSGPSNT 4725



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICW 1401
            S  I  + N     +++  EN+ G  DV      T     + P   +   I  + I + W
Sbjct: 5696 SAIITGLTNGQTYEFRVSAENDVGVGDVSDVATATPATASNAPTALSATAISGTEITLSW 5755

Query: 1402 DEPENTGNSTIIYYVVEYQEID------TTEWISVKNI-TKTQTSIQNLKTNSSYRFRAY 1454
              P+NTG   I  Y++E  + D      TT  +S+  + T T  +   L   ++Y +R  
Sbjct: 5756 IAPQNTGGFAITGYLIERHDGDGNFDDVTTLSVSLPPLPTDTTFTDTGLSQGTTYTYRVS 5815

Query: 1455 AVNEVDISDASET 1467
            AV ++    AS T
Sbjct: 5816 AVTQLGPGIASGT 5828



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%)

Query: 1382 SPPGKPNILEIDSS-----SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
            +P G P+   ID +      + + W+ P N G + I  Y++E  + +  E  +    T  
Sbjct: 1370 TPAGVPDAPVIDEALGGNGQVYLTWEHPPNNG-AAITDYIIEVNDGNGWEVFNDGTSTNR 1428

Query: 1437 QTSIQNLKTNSSYRFRAYAVN 1457
              ++ NL+   +Y FR  AVN
Sbjct: 1429 FVTVDNLENGETYSFRVKAVN 1449



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 10/134 (7%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID--SSSINICW 1401
            S  ++ +EN     +K+R  +          +  +   +P   P  LE    +  + + W
Sbjct: 5083 SYPVEDLENARTYSFKVRANSIASFGPFSNTLDAVPFTTP-NAPTDLEATRGNGEVTLQW 5141

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ----TSIQNLKTNSSYRFRAYAVN 1457
            ++P+  G S I  YVVEY           + +T +     T I  L   + Y FR  AVN
Sbjct: 5142 NKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAVN 5201

Query: 1458 ---EVDISDASETT 1468
               E  +SD +  T
Sbjct: 5202 AAGEGALSDIATAT 5215


>UniRef50_Q4STB1 Cluster: Chromosome 11 SCAF14249, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
            SCAF14249, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 495

 Score =  134 bits (323), Expect = 3e-29
 Identities = 98/380 (25%), Positives = 175/380 (46%), Gaps = 23/380 (6%)

Query: 1600 PPPE---VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            PP E   V W++ G+++++     I  +   S +  ++  RS + +  I+  N  G +  
Sbjct: 32   PPQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEIRIQIKNLFGVAEA 91

Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716
               L V D+PS PE PV   E +   + I+W PP DDGG  +T Y IE+ +   + W K+
Sbjct: 92   TSQLIVLDRPSPPEAPVETVETTSSIIVIKWNPPRDDGGSAVTNYIIERQQVGQSLWKKL 151

Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
             +V  D   +  + +    +Y +R+ A+N  G S++LE++  ++   + + S        
Sbjct: 152  GNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETKDSIMAGVM-ILSGPPGTPKV 210

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW----KXXXXXXXXXARIQKLSI 1831
              +    + +TW P E + G PII Y +E  K++  +W                +++++ 
Sbjct: 211  GSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIALNDVSDPIEDVKYAVKEVTE 270

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEP 1889
               Y+FR+ A NE G+  P      +        P    P +FVV  +   SV +K    
Sbjct: 271  GAEYEFRVSAINESGSGDPSPPSAMVCAKNPNLRPCFKDPEDFVVVRA-GNSVRVKVCY- 328

Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
            E+     IT ++ + + +    W +++   G + + CI + K  D  I+ I A+N+VG +
Sbjct: 329  EAEPPPEIT-WMKDDEPI--SPWIQVINTEG-MSQLCIPSSKRSDSAIYTIKAKNSVGEA 384

Query: 1950 LPTESQSVRLEKHATVPSPP 1969
            L        +E   TV SPP
Sbjct: 385  LHD------IEVRVTVHSPP 398



 Score =  102 bits (244), Expect = 1e-19
 Identities = 93/403 (23%), Positives = 167/403 (41%), Gaps = 23/403 (5%)

Query: 1282 EVVEFPPK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            +V EF  + +  + +   ++ G + T  + +         W      IK     K   + 
Sbjct: 1    DVPEFDTEDLCKFSKPVIVRVGQNATFKMSFPPQESLVVSWFREGSEIKDGGGVKIVREL 60

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI 1399
              + L  +    +DAG  +++++N  G A+    + +LD+PSPP  P   +E  SS I I
Sbjct: 61   NHSRLLFRDCLRSDAGEIRIQIKNLFGVAEATSQLIVLDRPSPPEAPVETVETTSSIIVI 120

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVN 1457
             W+ P + G S +  Y++E Q++  + W  + N++  +T    +N+     Y +R YA N
Sbjct: 121  KWNPPRDDGGSAVTNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAEN 180

Query: 1458 EVDISDASETTEYYK---VIKETKIQSP---TVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
            +  +SD+ ET +      +I      +P   +V K   N+T  P ED +   I G + + 
Sbjct: 181  QEGLSDSLETKDSIMAGVMILSGPPGTPKVGSVSKTCINLTWTPPEDDKGMPIIGYLLEK 240

Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVV 1565
            +     +   L       E+                ++  A N+ G  + S      C  
Sbjct: 241  RKKDTTEWIALNDVSDPIED-VKYAVKEVTEGAEYEFRVSAINESGSGDPSPPSAMVCAK 299

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
                +P      + +    + G+   V    E  PPPE+ W K+   +       +   E
Sbjct: 300  NPNLRPCFKDPEDFVVV--RAGNSVRVKVCYEAEPPPEITWMKDDEPI--SPWIQVINTE 355

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKP 1666
              S + I   KRS S+ YTI+A N+ G +   +EV + V+  P
Sbjct: 356  GMSQLCIPSSKRSDSAIYTIKAKNSVGEALHDIEVRVTVHSPP 398



 Score =  101 bits (242), Expect = 2e-19
 Identities = 104/473 (21%), Positives = 184/473 (38%), Gaps = 45/473 (9%)

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC------------ 1268
            P E+L V+W+++ S I+D     ++ ++    L+ R C   D  E               
Sbjct: 33   PQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEIRIQIKNLFGVAEAT 92

Query: 1269 ---VLLDAKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVT-LLVDYQAFPQPNDEWIV 1323
               ++LD  S  +  VE VE    I+  +    R   GS VT  +++ Q   Q   + + 
Sbjct: 93   SQLIVLDRPSPPEAPVETVETTSSIIVIKWNPPRDDGGSAVTNYIIERQQVGQSLWKKLG 152

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            N    K C   +     K  +  I   EN +     L  +++     +   V IL    P
Sbjct: 153  NVSADKTCFRDRNVTHGKKYNYRIY-AENQEGLSDSLETKDS-----IMAGVMILS--GP 204

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----KTQTS 1439
            PG P +  +  + IN+ W  PE+     II Y++E ++ DTTEWI++ +++      + +
Sbjct: 205  PGTPKVGSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIALNDVSDPIEDVKYA 264

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            ++ +   + Y FR  A+NE    D S  +    V  +     P  + P   +       +
Sbjct: 265  VKEVTEGAEYEFRVSAINESGSGDPSPPSA--MVCAKNPNLRPCFKDPEDFVVVRAGNSV 322

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
             +   +   P P++TW +D + +         E                 Y   A N  G
Sbjct: 323  RVKVCYEAEPPPEITWMKDDEPISPWIQVINTEGMSQLCIPSSKRSDSAIYTIKAKNSVG 382

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            E      V       +T+ +         G +  +T  + G P P V WY N   + +DK
Sbjct: 383  EALHDIEVR------VTVHSP------PKGYQLYMTCAVRGCPTPSVSWYLNDVCINSDK 430

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
             Y IT       + I  ++ + + +Y + A N+ G +     + V  K  + E
Sbjct: 431  NYYITNSCGVCSMYILRVRPTDNGEYKVVALNSLGKAECATKIIVRGKHIRTE 483



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            + RI  +N  G +    +  ++ +    +PP  P   V  E+TS  + +KW  P  +GGS
Sbjct: 77   EIRIQIKNLFGVA---EATSQLIVLDRPSPPEAPVETV--ETTSSIIVIKWNPPRDDGGS 131

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             +TNYIIE + V    W K+  V          N+    +  +RI AEN  G+S   E++
Sbjct: 132  AVTNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETK 191

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
               +     +  PP  P ++  V    +  +W  PE D G P++GY +  R    T W+ 
Sbjct: 192  DSIMAGVMILSGPPGTP-KVGSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIA 250

Query: 2016 VGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            +  V   +  +K+ +++++E   Y  R+ A NE G  +P
Sbjct: 251  LNDVSDPIEDVKYAVKEVTEGAEYEFRVSAINESGSGDP 289



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 5/119 (4%)

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
            RI  +N  GV+  T SQ + L++    PSPP AP+E     S+I++  W  P  DGG+ +
Sbjct: 79   RIQIKNLFGVAEAT-SQLIVLDR----PSPPEAPVETVETTSSIIVIKWNPPRDDGGSAV 133

Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
              Y I  + V +++W ++G V  +   F  R+++    Y  RIYA N+ GLS+ LE+ +
Sbjct: 134  TNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETKD 192



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 23/245 (9%)

Query: 700 VKKFQEGT---YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
           VK+  EG    + V A+N  G  + S P  +         P   +P   ++VR G SV +
Sbjct: 265 VKEVTEGAEYEFRVSAINESGSGDPSPPSAMVCAKNPNLRPCFKDPEDFVVVRAGNSVRV 324

Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
                  P P ITW K+++P+       + +  S   +   K  D  +YT+KA+NS G  
Sbjct: 325 KVCYEAEPPPEITWMKDDEPISPWIQVINTEGMSQLCIPSSKRSDSAIYTIKAKNSVG-- 382

Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
              A+  +E     ++ P  +              + +   V   P PS++WY N+  I+
Sbjct: 383 --EALHDIEVRVTVHSPPKGY-------------QLYMTCAVRGCPTPSVSWYLNDVCIN 427

Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
             +            + I  V    D+G+YK VA NS GK+    ++ +  + +     L
Sbjct: 428 SDKNYYITNSCGVCSMYILRV-RPTDNGEYKVVALNSLGKAECATKIIVRGKHIRTELTL 486

Query: 935 QKSYE 939
              YE
Sbjct: 487 MICYE 491



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 1/79 (1%)

Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           P G  +   C V G P P ++W+     I   +++ +  +   V ++ I  V P D G +
Sbjct: 398 PKGYQLYMTCAVRGCPTPSVSWYLNDVCINSDKNYYI-TNSCGVCSMYILRVRPTDNGEY 456

Query: 582 TCVAKNAAGFASSTTELIV 600
             VA N+ G A   T++IV
Sbjct: 457 KVVALNSLGKAECATKIIV 475



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 26/193 (13%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F        V  G+ + ++    A P P+I W+   E I P   I V     M   C 
Sbjct: 305 PCFKDPEDFVVVRAGNSVRVKVCYEAEPPPEITWMKDDEPISP--WIQVINTEGMSQLC- 361

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
              I + K+     YT+ A N  GEA   I +++      PP            +G  + 
Sbjct: 362 ---IPSSKRSDSAIYTIKAKNSVGEALHDIEVRVTV--HSPP------------KGYQLY 404

Query: 754 LSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
           ++  V G P P+++W  N    N       T S G   S+ IL+ +   D G Y + A N
Sbjct: 405 MTCAVRGCPTPSVSWYLNDVCINSDKNYYITNSCG-VCSMYILRVRPT-DNGEYKVVALN 462

Query: 810 SEGIAETSAVITV 822
           S G AE +  I V
Sbjct: 463 SLGKAECATKIIV 475



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 1118 VNKGNKATFEIELTKGDALV-RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            V  G  ATF++     ++LV  WF++GSEI+    +++  +    +L   DC   DAGE 
Sbjct: 19   VRVGQNATFKMSFPPQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEI 78

Query: 1177 SCEVGN 1182
              ++ N
Sbjct: 79   RIQIKN 84


>UniRef50_UPI0000660A1C Cluster: Homolog of Gallus gallus
            "Myosin-binding protein C, fast-type (Fast MyBP-C)
            (C-protein, skeletal muscle fast-isoform).; n=1; Takifugu
            rubripes|Rep: Homolog of Gallus gallus "Myosin-binding
            protein C, fast-type (Fast MyBP-C) (C-protein, skeletal
            muscle fast-isoform). - Takifugu rubripes
          Length = 844

 Score =  132 bits (320), Expect = 8e-29
 Identities = 105/469 (22%), Positives = 207/469 (44%), Gaps = 20/469 (4%)

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF--EKRGHIRKLY 1075
            +F+ K+QD + +E++ A+ E  I+     + W +   I   +  K+D    +   I  L 
Sbjct: 269  DFLYKIQDVKAEEREDAVFECVISQPLKKITW-KGKNIPLEQGEKFDILVSEDMLIHTLV 327

Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGD 1134
            +++    D+G Y+ +    SC+A + V E   E   R++ + K     +A  +++  K  
Sbjct: 328  VKDCMPLDKGIYAAVAGLASCSAWLVVEE--SEAKARVEAEIKAKARAEAKAKLKAKKKS 385

Query: 1135 ALVRWFKDGSEI--QFSNHIQLTID----GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
            +     K+  ++  +     +L+ D    G  ++++  + D +D  +   E   S    +
Sbjct: 386  SATEKGKEKQKMVKKAKAKAELSADSEDKGDSEEIEDIEEDTNDDNDMDGEQEESVKEDV 445

Query: 1189 LTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247
              V   + + FT  L +   +    +A L  ++  E  D  WYK    I  T++  ++ D
Sbjct: 446  EGVPTGAGVYFTSGLCDVTAI-LGANAELVCKLSSEECDGVWYKDGKEITATDEICIVKD 504

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF--PPKIVDYEREYRIKRGSDV 1305
               R LII+ C E+D  +Y C     K+   LKVE      P  + ++++  +IK G   
Sbjct: 505  HNFRKLIIKNCKEEDAGKYRCEADGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSA 564

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
            TL + +        +W    + + +  + K    S    L + K     +G  K++++N 
Sbjct: 565  TLKISFVGREPMKVQWYHEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNE 624

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
            CG  +   ++ +L  P PP  P I+      IN+ W  P NTG + ++ Y VE ++  + 
Sbjct: 625  CGTTEATTDIVVLAFPGPPAAPKIVSAFKDCINLVWIAPSNTGGTNLLGYNVEKRKNGSN 684

Query: 1426 EWISV----KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
             W  V    + I + + +++++     Y FR  A+N     + S  +E+
Sbjct: 685  LWSFVNPPDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSPPSEF 733



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 87/386 (22%), Positives = 137/386 (35%), Gaps = 24/386 (6%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXX 1543
            L ++T     + EL C         V WY+DGK++            N            
Sbjct: 460  LCDVTAILGANAELVCKLSSEECDGV-WYKDGKEITATDEICIVKDHNFRKLIIKNCKEE 518

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-----KHKVGDEWLVTAVIEG 1598
                Y+C A    G  +T  ++ ++  P   I+ +D+K+     K K G    +     G
Sbjct: 519  DAGKYRCEA---DGR-KTEAMLKVEDPP--RINPDDLKEFQKPVKIKTGKSATLKISFVG 572

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
              P +V WY  G +L  D    I      + + + + +R  S +  I+  N  GT+    
Sbjct: 573  REPMKVQWYHEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEATT 632

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
             + V   P  P  P I+    ++ + + W  P + GG  L  Y +EK +  +N W  V  
Sbjct: 633  DIVVLAFPGPPAAPKIVSAF-KDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNP 691

Query: 1719 VDRDV--ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
             D  +  + Y ++ + E  EY FRV A N  G  E       V       P         
Sbjct: 692  PDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRV 751

Query: 1777 XXIDNESVYITWF--PSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXXXARIQKLSI 1831
                  ++ + W     E+        Y VE +  E  +W              I  L  
Sbjct: 752  TDSTYTTLSLGWTKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKS 811

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKI 1857
               Y  R+ A NE G   P   D+ I
Sbjct: 812  MAMYWVRVVATNEGGDGEPQDLDNYI 837



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 179/861 (20%), Positives = 326/861 (37%), Gaps = 75/861 (8%)

Query: 937  SYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD- 993
            S   +EGK V+       + T +  W  N  EI    H+ +  +G             D 
Sbjct: 16   SITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSGEHQLQIPDVSADE 75

Query: 994  VGVIKCIVKDQE-----TSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047
                KC   ++      T+T+ V++ E   + ++   D + KE++    ++E + +  +V
Sbjct: 76   ADTYKCFATNEYGKAIVTATLNVIEAEDFKKALKNKIDIDAKEEN----KMEADEKFFEV 131

Query: 1048 VW---ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104
            +    ++D E I  +    DF  RG ++KL      +  E E   +L       +   V 
Sbjct: 132  LMSAEKKDYESICIQYGVTDF--RGMLKKL--NEKKIEREKEQEKVLFPHVFFLKEYRVN 187

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
                  T + N       K TF   L K D ++  F   ++I+      L   GKK    
Sbjct: 188  ------TMIWNLIFLLCWKMTFSSLLFKQDGVMIPFDADTDIKHG----LKQVGKKYVFS 237

Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224
            I   D +D+G Y  EV   K  +    + P+++F  ++ + +      DA     I    
Sbjct: 238  INGVDPEDSGLYQVEVDGVKVFS-TDFKVPNVDFLYKIQD-VKAEEREDAVFECVISQPL 295

Query: 1225 LDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
              +TW  K   +E  EKF ++   D+   TL+++ C   D+  Y  V   A  +  L VE
Sbjct: 296  KKITWKGKNIPLEQGEKFDILVSEDMLIHTLVVKDCMPLDKGIYAAVAGLASCSAWLVVE 355

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDS- 1340
              E   ++   E E + K  ++    +  +      ++     K++KK K   + S DS 
Sbjct: 356  ESEAKARV---EAEIKAKARAEAKAKLKAKKKSSATEKGKEKQKMVKKAKAKAELSADSE 412

Query: 1341 -KSASLTIKKV-ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
             K  S  I+ + E+T+        +      DVE   T        G  ++  I  ++  
Sbjct: 413  DKGDSEEIEDIEEDTNDDNDMDGEQEESVKEDVEGVPTGAGVYFTSGLCDVTAILGANAE 472

Query: 1399 -ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAV 1456
             +C    E       ++Y  + +EI  T+ I  VK+    +  I+N K   + ++R  A 
Sbjct: 473  LVCKLSSEECDG---VWY-KDGKEITATDEICIVKDHNFRKLIIKNCKEEDAGKYRCEA- 527

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
                  D  +T    KV    +I    +++  K +  +  +   L   F G    KV WY
Sbjct: 528  ------DGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSATLKISFVGREPMKVQWY 581

Query: 1517 RDGKK-LKTAKATYENRXXXXXXXXX---XXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
             +G++ L+      E                     K    N+ G  E +  + +   P 
Sbjct: 582  HEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEATTDIVVLAFPG 641

Query: 1573 ITISNEDIKQ-KHKVGDEWLVTAVIEG--IPPPEVIWYKNGNKL---ENDKEYNITTKEK 1626
               + + +   K  +   W+  +   G  +    V   KNG+ L    N  +  I  K+ 
Sbjct: 642  PPAAPKIVSAFKDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNPPDEPIREKK- 700

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-VYDK-PSKPEGPVIMREISRESVT 1684
                 +K++      ++ + A N +G+       + V+ + P KP G VI   ++  + T
Sbjct: 701  ---YAVKDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRVTDSTYT 757

Query: 1685 ---IEWKPPLDDGGL--ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
               + W  P ++  +  E   Y +E    ++  W +       + +Y I  L     Y  
Sbjct: 758  TLSLGWTKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKSMAMYWV 817

Query: 1740 RVIAQNPVGFSEALESEPIVI 1760
            RV+A N  G  E  + +  +I
Sbjct: 818  RVVATNEGGDGEPQDLDNYII 838



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 79/369 (21%), Positives = 141/369 (38%), Gaps = 41/369 (11%)

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT----- 1659
            +WYK+G ++    E  I        + IK  K   + KY  EA      + ++V      
Sbjct: 485  VWYKDGKEITATDEICIVKDHNFRKLIIKNCKEEDAGKYRCEADGRKTEAMLKVEDPPRI 544

Query: 1660 ----LKVYDKPSKPE-GPVIMREIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
                LK + KP K + G     +IS   RE + ++W    ++  LE T   IEK      
Sbjct: 545  NPDDLKEFQKPVKIKTGKSATLKISFVGREPMKVQWYHEGEEL-LEDTNIKIEKSSTHTQ 603

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
                       V T C +K +       ++  +N  G +EA  +  IV+      P+   
Sbjct: 604  L----------VLTKCRRKSSGE----IKIKIKNECGTTEA--TTDIVVLAFPGPPAAPK 647

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI 1831
                      + + + W      GG+ ++ Y VE ++ G              R +K ++
Sbjct: 648  IVSAF----KDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNPPDEPIREKKYAV 703

Query: 1832 NTT-----YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
                    Y+FR+ A N  G+  P    + +       PP +  +  V++ST  +++L W
Sbjct: 704  KDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRVTDSTYTTLSLGW 763

Query: 1887 TEP--ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
            T+P  E         Y +EF+  +   W++  +    ++ + I  +K       R+ A N
Sbjct: 764  TKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKSMAMYWVRVVATN 823

Query: 1945 TVGVSLPTE 1953
              G   P +
Sbjct: 824  EGGDGEPQD 832



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 14/237 (5%)

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
            + +I  +NE GT+   T+D  I +     PP+ P+  +VS +    + L W  P + GG+
Sbjct: 616  EIKIKIKNECGTT-EATTD--IVVLAFPGPPAAPK--IVS-AFKDCINLVWIAPSNTGGT 669

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPTE 1953
             +  Y +E +      W+ +      + E  + ++++ E  E  FR+SA N  G   P+ 
Sbjct: 670  NLLGYNVEKRKNGSNLWSFVNPPDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSP 729

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS--WGTP--EWDGGAPLLGYNIAIRDVT 2009
                   +      PP   +++R+  S     S  W  P  E +      GY +  R   
Sbjct: 730  PSEFVFARDPK--KPPGKVIDLRVTDSTYTTLSLGWTKPKEEEEVQDEAKGYFVEFRPAE 787

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
               W       +    + I  L     Y +R+ A NE G  EP + D     +P  G
Sbjct: 788  DPEWSRCNSSAIIMNSYTIMGLKSMAMYWVRVVATNEGGDGEPQDLDNYIIAMPPPG 844



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 3/115 (2%)

Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886
           E    P F  +   IT++E   +   A V  NP P++TW RNN EI      I  +    
Sbjct: 3   EGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSG 62

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
             +L I +V ++ ++  YKC A+N  GK+   A + + +E   F K L+   + +
Sbjct: 63  EHQLQIPDVSAD-EADTYKCFATNEYGKAIVTATLNV-IEAEDFKKALKNKIDID 115



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 82/360 (22%), Positives = 138/360 (38%), Gaps = 34/360 (9%)

Query: 758  VVGNPRPTITWCKNNKPVKA-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            V+  P   ITW   N P++      +    D   H++ ++K     D+G+Y   A    G
Sbjct: 290  VISQPLKKITWKGKNIPLEQGEKFDILVSEDMLIHTL-VVKDCMPLDKGIYAAVA----G 344

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-- 870
            +A  SA + VEE +E  A     I        K K   K  +  T          +    
Sbjct: 345  LASCSAWLVVEE-SEAKARVEAEIKAKARAEAKAKLKAKKKSSATEKGKEKQKMVKKAKA 403

Query: 871  --EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEK 927
              E+ + SE    + + E+IE   TN D+++D    + V  +  G  +  G   T  +  
Sbjct: 404  KAELSADSEDKGDSEEIEDIE-EDTNDDNDMDGEQEESVKEDVEGVPTGAGVYFTSGLCD 462

Query: 928  VTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            VT +           G    L C+ +S      WY + KEI+  D   I+++        
Sbjct: 463  VTAIL----------GANAELVCKLSSEECDGVWYKDGKEITATDEICIVKDHNFRKLII 512

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRKLQ-DFEVKEKDVAILEVE-IN 1041
                  D G  +C    ++T  ML V++     P+ +++ Q   ++K    A L++  + 
Sbjct: 513  KNCKEEDAGKYRCEADGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSATLKISFVG 572

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
             E   V W  +GE +    N    EK     +L +        GE    +++E  T E T
Sbjct: 573  REPMKVQWYHEGEELLEDTN-IKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEAT 631



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 10/104 (9%)

Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTK 781
           I  G   P    +P+ S+ +++G+ V+  A VVGNP PT+TW +NN  +     K L  K
Sbjct: 1   IPEGMSTPDFTRKPI-SITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDK 59

Query: 782 SDGDTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEE 824
             G+ H + I  P    DE   Y   A N  G A  +A + V E
Sbjct: 60  GSGE-HQLQI--PDVSADEADTYKCFATNEYGKAIVTATLNVIE 100



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 1/99 (1%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           E    P F  K       +G  V F   V G P P +TW R    I   +   +Y     
Sbjct: 3   EGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSG 62

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEA 602
              L I +V  ++A T+ C A N  G A  T  L ++EA
Sbjct: 63  EHQLQIPDVSADEADTYKCFATNEYGKAIVTATLNVIEA 101



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 4/105 (3%)

Query: 628 ILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
           I EG+  P F++KP +  + EG  ++    +V  P P + WL    EI  DE   +  + 
Sbjct: 1   IPEGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEI-GDERHKILYDK 59

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
               +   L+I +V   +  TY   A N  G+A +   L +   E
Sbjct: 60  GSGEH--QLQIPDVSADEADTYKCFATNEYGKAIVTATLNVIEAE 102



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VATLVI 570
           F+ K++     +     FEC +   P  +ITW  +   ++  + F +   +D  + TLV+
Sbjct: 270 FLYKIQDVKAEEREDAVFECVIS-QPLKKITWKGKNIPLEQGEKFDILVSEDMLIHTLVV 328

Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           ++  P D G +  V    AG AS +  L+VE
Sbjct: 329 KDCMPLDKGIYAAV----AGLASCSAWLVVE 355


>UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-like
            protein 1 precursor; n=63; Euteleostomi|Rep: Down
            syndrome cell adhesion molecule-like protein 1 precursor
            - Homo sapiens (Human)
          Length = 2053

 Score =  130 bits (314), Expect = 4e-28
 Identities = 317/1535 (20%), Positives = 562/1535 (36%), Gaps = 164/1535 (10%)

Query: 512  FVEKLRPKHTPDGSTVQFECQVEGYPRPQIT---WFRQTAIIKPSQDFQMYYDDDNVATL 568
            +  ++  + +  G+   F+C +    +  ++   W + T  I P   F + Y       L
Sbjct: 127  YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGG----L 182

Query: 569  VIREVFPEDA-GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
             I +V  EDA  T+ C+ K+   ++  T +         +G+ ++V             D
Sbjct: 183  YISDVQKEDALSTYRCITKHK--YSGETRQ--------SNGARLSVT------------D 220

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
              E IP T      +Q V  G  + L C     P P I WL  G  +  D   +  I   
Sbjct: 221  PAESIP-TILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG- 278

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
                   L I++++    GTY     N  G A    +L +     +P  V    K +   
Sbjct: 279  -------LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI----DPLHVTLTPKKLKTG 327

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYT 804
             G +VILS  + G+P  TI W +N + V  LP ++    G ++   ++   +    G Y 
Sbjct: 328  IGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLITSAQKSHSGAYQ 385

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A      A+  A+I +E+ T      P  ++ F E  V       L+      P P++
Sbjct: 386  CFATRKAQTAQDFAIIALEDGT------PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTV 439

Query: 865  TWYRNNE-IISPSETITQNF---DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            TW  ++E I+      T  +   DG  I  +        D G Y+C A N  G + + AR
Sbjct: 440  TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 499

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978
              I+V     ++ + ++     G+  ++ C+       S KWY +   +   +HR+++ E
Sbjct: 500  --INVRGPPSIRAM-RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPD-NHRQVVFE 555

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA-ILE 1037
                          D G   C V  Q   ++        +    +Q FE     +  +L 
Sbjct: 556  -NGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLY 614

Query: 1038 VEINSETAD----VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            +     + D    + W +DG++I    +    E +  +  L I + S+   G Y+CI  +
Sbjct: 615  IPCVVSSGDMPIRITWRKDGQVI-ISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 673

Query: 1094 ESCTA---EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149
             + T       +V +PP  + +  NQ    G        +       V W          
Sbjct: 674  AAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQ 733

Query: 1150 NHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNSKCTAI-----LTVEEPSINFT 1199
             +  + + G+ Q      L I     +D G Y C+  N   T I     LTV+ P++  T
Sbjct: 734  QYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAM-IT 792

Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE--KFTLIS----DVKKRTL 1253
                  I +  +          +  + + W K  +VI+     ++ + +    D    TL
Sbjct: 793  SHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTL 852

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312
             ++     D   ++C  +++    +  +++ V+ PP     E E R  +   + L    Q
Sbjct: 853  KLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPD--PPELEIREVKARSMNLRWT-Q 909

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTD---AGIYKLRLE--NN 1365
             F    +  I    I  K K         +++ S TI +    D   A +Y +R+   N 
Sbjct: 910  RF--DGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNK 967

Query: 1366 CGHADVEMNVTI-LDKPSPPGKP---NILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQ 1420
             G ++    +TI  ++ +P G P    +  + S SI + W  P +   N  I  Y + Y+
Sbjct: 968  IGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR 1027

Query: 1421 EID--TTEWISVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASE-----TTE 1469
            E    +    S+  +  T  S    + NLK  + Y     A N      +S      T E
Sbjct: 1028 ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLE 1087

Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
                     +++ ++   +  I+        L  +  G      + Y DG+  +    T 
Sbjct: 1088 DVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNIT- 1146

Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK----QKHK 1585
              R                + +A+   G+   S V+ IQ K  +      IK        
Sbjct: 1147 TTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASS 1206

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            V   WL      G+     I+  + G+      EY   T  +    RI  L R       
Sbjct: 1207 VVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE--TSPEQLFYRIAHLNRGQQYLLW 1264

Query: 1645 IEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEW----KPPLDDGGLE 1697
            + A  +A  G SS +VT+       +P G    + IS   +VT  W    + P +  G  
Sbjct: 1265 VAAVTSAGRGNSSEKVTI-------EPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1317

Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
                   K   D+   + + D  R +    T  ++ +       +   A N  GF     
Sbjct: 1318 APAVKWTKDSEDSAIPVSM-DGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGF----- 1371

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW 1813
             + I++   + VP               S+ +TW P + NGGS I  + ++      ++W
Sbjct: 1372 -DTIIVNLLVQVPPDQPRLTVSKT-SASSITLTWIPGD-NGGSSIRGFVLQYSVDNSEEW 1428

Query: 1814 KXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
            K         + ++  L   T Y+ ++ A+N +G+       +  T G+  +       F
Sbjct: 1429 KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLF 1488

Query: 1873 VVSESTSRSVTLK-WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
                ST   + L+ W    +NGG PIT  ++E++  KG +W        S  E  +  ++
Sbjct: 1489 THINSTHARLNLQGW----NNGGCPITAIVLEYRP-KG-TWAWQGLRANSSGEVFLTELR 1542

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
            E      R+ A N+ G    T   +      +T+P
Sbjct: 1543 EATWYELRMRACNSAGCGNETAQFATLDYDGSTIP 1577



 Score =  120 bits (289), Expect = 4e-25
 Identities = 221/1098 (20%), Positives = 417/1098 (37%), Gaps = 124/1098 (11%)

Query: 1022 KLQDFEVKEKDVAILEVEINSETADVV----WERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
            +++D      +VA+ +  I S   + V    WE+D   I P+   +     G    LYI 
Sbjct: 130  RVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGG----LYIS 185

Query: 1078 NTSVHDE-GEYSCILRD-------ESCTAEVTVV---ELPPEIITRLQNQKVNKGNKATF 1126
            +    D    Y CI +        +S  A ++V    E  P I+    +Q+V  G+  T 
Sbjct: 186  DVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGH--TV 243

Query: 1127 EIELTKGD---ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--- 1180
            E+  T        +RW KDG  +   +     I G    L I D   +D+G Y CEV   
Sbjct: 244  ELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEVTNT 299

Query: 1181 -GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIED 1238
             G+++ T IL V +P ++ TL  P+ +     +   L+  +       + WY+   ++  
Sbjct: 300  FGSAEATGILMVIDP-LHVTLT-PKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLP 357

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYERE 1296
             E  + I  +   TL+I    +     Y C       T +    + + +  P+IV    E
Sbjct: 358  DEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 416

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT--- 1353
              +  G   +L+   +  P P   W ++ + I +    + +  + S   TI  +  T   
Sbjct: 417  KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQ 476

Query: 1354 --DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
              D G+Y+    N  G A+ +  + +   PS     NI  +      I      N     
Sbjct: 477  IRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLI------NCRVIG 530

Query: 1412 IIYYVVE-YQEI----DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
              YY ++ Y++     D    +  +N T   T +Q       Y        ++ IS +  
Sbjct: 531  YPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVH 590

Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525
                        ++ P + +P +       + + + C+      P ++TW +DG+ + + 
Sbjct: 591  VA----------VKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG 640

Query: 1526 KA-TYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEV--ETSCVVGIQQKPVITISNED 1579
               T E++                  Y CIA N    V  E   +V +  + V+  +N+D
Sbjct: 641  SGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD 700

Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN---ITTKEK---TSVIRIK 1633
                   G   ++   ++G PPP+V+W K+     N ++Y+   +T + +    S + I+
Sbjct: 701  ----GIYGKAGVLNCSVDGYPPPKVMW-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIR 755

Query: 1634 ELKRSHSSKYTIEASNTAGTS---SVEVTLKVYDK-PSKPEGPVIMREISRE-SVTIEWK 1688
             +       Y  +ASN  GT    S+ +T+K+     S P   + ++  ++E + T   +
Sbjct: 756  HVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGE 815

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD-----VETYCIQKLNENCEYMFRVIA 1743
             P+      + ++       D +R ++ A   +D     V T  ++  +      F   A
Sbjct: 816  RPI------IIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHA 869

Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
             N  G    L    + ++   D P           +   S+ + W     +G S I  + 
Sbjct: 870  INSYGEDRGLIQ--LTVQEPPDPPELEIRE-----VKARSMNLRW-TQRFDGNSIITGFD 921

Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIGTSLPYTSDDKIT 1858
            +E K +   W            I + +I      + Y  R+Y+ N+IG S P     ++T
Sbjct: 922  IEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEP---SKELT 978

Query: 1859 IG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKT----VKGKSW 1912
            I  +   P   P +  +   TS+S+ + W  P+       I  Y I ++       G+  
Sbjct: 979  ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYS 1038

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
               +   G    + ++N+K+  +    + A N  G   P+ S+ +       VPS P   
Sbjct: 1039 IVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSE-INATTLEDVPSQPPEN 1096

Query: 1973 LEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV-TKTMWMEVGKVDVNTLKFNIRD 2030
            +    + S++ + SW  P        L GY +    +     W E+  +     +  +R 
Sbjct: 1097 VRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRG 1156

Query: 2031 LSENHTYMIRIYARNEIG 2048
            + +   Y +++ A  + G
Sbjct: 1157 MEKFTNYSVQVLAYTQAG 1174



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 157/749 (20%), Positives = 266/749 (35%), Gaps = 49/749 (6%)

Query: 651  ILLECRLVAIPEPDIAW-LFKGEEIVPDENIS-VAIESDMHMYCSVLKITNVKKFQEGTY 708
            +++ C     P   + W L  G++I    +I  V     + +Y       N     +  Y
Sbjct: 43   VVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFN-SFIHDNDY 101

Query: 709  TVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
               A N  G+   P + ++K   +EP  V +E  +SM         L    V      ++
Sbjct: 102  FCTAENAAGKIRSPNI-RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVS 160

Query: 768  WCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
            W K+     P         G  +   + K   +      T    + E      A ++V +
Sbjct: 161  WEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTD 220

Query: 825  PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
            P E     P  ++ F    V    T++L    +  P+P+I W ++   +      T+   
Sbjct: 221  PAESI---PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 277

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEG 943
            G    L I+++ +E DSG Y C  +N+ G + + G  + ID   VT      K  +T  G
Sbjct: 278  G----LTISDLRTE-DSGTYICEVTNTFGSAEATGILMVIDPLHVTLTP---KKLKTGIG 329

Query: 944  KTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             TVIL C    S   + +WY N  E+   D    I+                 G  +C  
Sbjct: 330  STVILSCALTGSPEFTIRWYRNT-ELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388

Query: 1002 -KDQETS---TMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVVWERDGEII 1056
             +  +T+    ++ +++  P  +    +  V   +  +++     +    V W  D E I
Sbjct: 389  TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI 448

Query: 1057 ----KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI 1109
                  + N+Y       I  + +    + D G Y C  R+   +AE      V  PP I
Sbjct: 449  VRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSI 508

Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
               ++N     G        +       ++W+KD   +   NH Q+  +    KL     
Sbjct: 509  -RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP-DNHRQVVFENGTLKLTDVQK 566

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL----TVEIPDET 1224
             +D+ GEY C V      +I      ++     +  F   PA+    L     V   D  
Sbjct: 567  GMDE-GEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMP 625

Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-V 1283
            + +TW K   VI      T+ S     +L I   +      YTC+  +A +T   + + +
Sbjct: 626  IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLI 685

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDS-- 1340
            V  PP+ V          G    L      +P P   W         +  H  P      
Sbjct: 686  VRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQ 745

Query: 1341 --KSASLTIKKVENTDAGIYKLRLENNCG 1367
               ++SL I+ V   D G Y  +  N  G
Sbjct: 746  ILPNSSLLIRHVLEEDIGYYLCQASNGVG 774



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 96/440 (21%), Positives = 167/440 (37%), Gaps = 36/440 (8%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678
            NITT  +   +R  E   ++S +  + A   AG       L +  K   P  P  ++ + 
Sbjct: 1144 NITTTRERVELRGMEKFTNYSVQ--VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVP 1201

Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736
             S  SV + W PP    G+ + KY I    P + +      +   +   Y I  LN   +
Sbjct: 1202 SSASSVVVSWLPPTKPNGV-IRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQ 1260

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y+  V A    G   +  SE + I+ A   P+              +V   W    +   
Sbjct: 1261 YLLWVAAVTSAGRGNS--SEKVTIEPAGKAPAKIISFGG-------TVTTPWMKDVRLPC 1311

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
            + + D    +K                 R+  +  N T   R     + G    T+    
Sbjct: 1312 NSVGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVKAEDSGYYTCTATNTG 1369

Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
              D I +   +  PP QPR   VS++++ S+TL W  P  NGGS I  +++++     + 
Sbjct: 1370 GFDTIIVNLLVQVPPDQPR-LTVSKTSASSITLTWI-PGDNGGSSIRGFVLQYSVDNSEE 1427

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS---P 1968
            W K V +  S     ++++K       +++A+N+VG      S+ +  + H   PS    
Sbjct: 1428 W-KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG--RISEIIEAKTHGREPSFSKD 1484

Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028
                  I    + + +  W     +GG P+    +  R   K  W   G    ++ +  +
Sbjct: 1485 QHLFTHINSTHARLNLQGWN----NGGCPITAIVLEYR--PKGTWAWQGLRANSSGEVFL 1538

Query: 2029 RDLSENHTYMIRIYARNEIG 2048
             +L E   Y +R+ A N  G
Sbjct: 1539 TELREATWYELRMRACNSAG 1558



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 5/108 (4%)

Query: 499  EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQD 555
            EK T E    AP  +        TP    V+  C   G P P + W + +  + I  S D
Sbjct: 1278 EKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMD 1337

Query: 556  FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
                   +   TL++R V  ED+G +TC A N  GF +    L+V+ P
Sbjct: 1338 GHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
            TV  PP  P LEIR V +  +   W T  +DG + + G++I  ++ + +   +    +++
Sbjct: 883  TVQEPPDPPELEIREVKARSMNLRW-TQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 941

Query: 2023 TL--KFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                + NI DL     Y IR+Y+ N+IG SEP
Sbjct: 942  PTINQANIVDLHPASVYSIRMYSFNKIGRSEP 973



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 5/95 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P  ++    +    G TV+  C   GYP P I W +    +     +        +  L 
Sbjct: 226 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTK-----RITGLT 280

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
           I ++  ED+GT+ C   N  G A +T  L+V  PL
Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPL 315


>UniRef50_UPI0000E8095E Cluster: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein; n=1;
            Gallus gallus|Rep: PREDICTED: similar to novel
            immunoglobulin I-set domain containing protein - Gallus
            gallus
          Length = 561

 Score =  129 bits (312), Expect = 7e-28
 Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 4/280 (1%)

Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKR 1068
            M V  E   +F+R L D   +  +  +L  E+     DVVW +DG +++P   + +   +
Sbjct: 280  MAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARR-EVRVQ 338

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFE 1127
            G  R L +      D GEY C   D+   A +TV V    EII  LQ+  V +G+ ATF+
Sbjct: 339  GRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATFK 398

Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
              ++  D +V W  DG  +  S  +Q+   G    L +  C   DA   +        TA
Sbjct: 399  CMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLSTA 458

Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247
             L+V+E  + F  +L + ++     D  L VE+  E  +V W K+  +++  +K+ +   
Sbjct: 459  RLSVQEAQVLFVRKLRD-VVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRES 517

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287
              +RTL IR  +  D+  Y C  L  ++  KL VE  E+P
Sbjct: 518  GCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVE-REYP 556



 Score =  115 bits (277), Expect = 1e-23
 Identities = 117/528 (22%), Positives = 200/528 (37%), Gaps = 39/528 (7%)

Query: 864  ITWYRNNEIIS----PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            + WY++ E +     P E +     G   EL  +      DSG Y C A++    +S   
Sbjct: 17   VKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPG-DSGCYVCDAASDRMVTS--V 73

Query: 920  RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978
             V     ++   +  Q   E +EG +V L  Q S  T + +W  + + +       +  E
Sbjct: 74   EVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGGRLLVCSE 133

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE---VKEKDVAI 1035
            G             D G   C   D E    L VKE    F+ K ++ E   V E   A+
Sbjct: 134  GPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAV 193

Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094
            L   ++ E ADV W    ++  P + +      G +  L + N +  D G Y+C+  D+ 
Sbjct: 194  LSAVVSKEQADVTWLCPRQLAVPSE-RCQLRCDGRVHSLVLSNVAKEDAGVYTCLSPDDQ 252

Query: 1095 -----------------------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131
                                   +CT      EL  + +  L + +  +G       EL 
Sbjct: 253  MQFDISVRGEHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSDVRARRGETVVLWCELC 312

Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191
            K    V W KDG  ++     ++ + G+++ L +     +DAGEY CE  + +  A LTV
Sbjct: 313  KAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTV 372

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            +   +   +   + ++V    DA     +  E + VTW      +  +E+  +       
Sbjct: 373  QVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCH 432

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
            +L +R C   D    T       ST +L V+  E     V   R+   +   DV L V+ 
Sbjct: 433  SLTVRGCQPSDAATVTANAEGLLSTARLSVQ--EAQVLFVRKLRDVVAEEQQDVCLEVEV 490

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
             +      +W+    +++              +LTI+ V  +D G Y+
Sbjct: 491  -SHEAAEVQWLKQGVLLQPGDKYLMRESGCRRTLTIRSVSPSDRGTYR 537



 Score =  105 bits (252), Expect = 1e-20
 Identities = 138/576 (23%), Positives = 235/576 (40%), Gaps = 59/576 (10%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIV----PDENISVAIESDMHMYCSVLKITNVKKFQE 705
            D++LE +L +    ++ W   GE++     P E + +     +      L  +  +    
Sbjct: 3    DLVLEVQL-SHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRE----LPQSGAQPGDS 57

Query: 706  GTYTVVAVNREGEASLPIVLK-IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            G Y   A +     S+ +  + ++   KE  Q   PL+   V++G+SV L AQ+  +P  
Sbjct: 58   GCYVCDAASDRMVTSVEVPAQAVRIVNKEEAQ--SPLE---VQEGDSVTLVAQL--SPET 110

Query: 765  TIT-WCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
                W K+ + + +   L   S+G   S+TI K  ++ D G +   A    G  E    +
Sbjct: 111  AAAQWQKDGQMLLSGGRLLVCSEGPARSLTI-KQVELGDAGTFLCDA----GDDEVYFTL 165

Query: 821  TVEEPTEENAEPPLFINRFQE---ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877
             V+E       P LF+N+ +E   + V E G+  L A V++     +TW    ++  PSE
Sbjct: 166  HVKEA------PVLFVNKQEEREKLLVLEGGSAVLSAVVSKEQA-DVTWLCPRQLAVPSE 218

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNS------AGKSSH--------GARVTI 923
                  DG    LV++NV  E D+G Y C++ +       + +  H        GAR T 
Sbjct: 219  RCQLRCDGRVHSLVLSNVAKE-DAGVYTCLSPDDQMQFDISVRGEHWWLWGAQRGARGTC 277

Query: 924  DVEKVTF---VKHLQ--KSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977
             +  V     VK L+         G+TV+L C+         W  + + +     RE+  
Sbjct: 278  TLMAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRV 337

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQET-STMLVVKETIPEFIRKLQDFEVKEKDVAIL 1036
            +GR            D G   C   D  T +T+ V    + E I +LQ   V E D A  
Sbjct: 338  QGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATF 397

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
            +  ++ E   V W+ DG  + P + +    + G    L +R     D    +        
Sbjct: 398  KCMVSPEDVVVTWQLDGRPVVPSE-RLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLS 456

Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156
            TA ++V E     + +L++    +      E+E++   A V+W K G  +Q  +   +  
Sbjct: 457  TARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRE 516

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
             G ++ L I      D G Y CE  + +    L+VE
Sbjct: 517  SGCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVE 552



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 105/464 (22%), Positives = 186/464 (40%), Gaps = 38/464 (8%)

Query: 645  VDEGSDILLECRLVAIPEPDIA-WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V EG  + L  +L   PE   A W   G+ ++    + V  E         L I  V+  
Sbjct: 94   VQEGDSVTLVAQLS--PETAAAQWQKDGQMLLSGGRLLVCSEGPARS----LTIKQVELG 147

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
              GT+   A    G+  +   L +K          E  + ++V +G S +LSA VV   +
Sbjct: 148  DAGTFLCDA----GDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAVLSA-VVSKEQ 202

Query: 764  PTITW-CKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-- 818
              +TW C      P +    + DG  HS+ +    K +D GVYT  + + +   + S   
Sbjct: 203  ADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAK-EDAGVYTCLSPDDQMQFDISVRG 261

Query: 819  ----VITVEEPTEEN-------AEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
                +   +             AE  + F+    ++  +   T+ L   + +     + W
Sbjct: 262  EHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAH-GDVVW 320

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             ++  ++ P         G    LV++ V  E D+G+Y C +++        A +T+ V 
Sbjct: 321  LKDGRVLEPDARREVRVQGRERSLVLSCVGPE-DAGEYCCESNDDRTL----ATLTVQVR 375

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            +V  +    +S    EG     +C  S   V   W  + + +   +  ++ + G      
Sbjct: 376  RVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLT 435

Query: 986  XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045
                   D   +    +   ++  L V+E    F+RKL+D   +E+    LEVE++ E A
Sbjct: 436  VRGCQPSDAATVTANAEGLLSTARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAA 495

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            +V W + G +++P  +KY   + G  R L IR+ S  D G Y C
Sbjct: 496  EVQWLKQGVLLQP-GDKYLMRESGCRRTLTIRSVSPSDRGTYRC 538



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 65/249 (26%), Positives = 116/249 (46%), Gaps = 14/249 (5%)

Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYD---FEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
            +LEV+++    +V W +DGE ++   +  +      RG +R+L        D G Y C  
Sbjct: 5    VLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVC-- 62

Query: 1092 RDESCTAEVTVVELPPE---IITRLQNQ---KVNKGNKATFEIELTKGDALVRWFKDGSE 1145
             D +    VT VE+P +   I+ + + Q   +V +G+  T   +L+   A  +W KDG  
Sbjct: 63   -DAASDRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQM 121

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP-- 1203
            +     + +  +G  + L I   +L DAG + C+ G+ +    L V+E  + F  +    
Sbjct: 122  LLSGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEER 181

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
            E +LV     A L+  +  E  DVTW   + +   +E+  L  D +  +L++    ++D 
Sbjct: 182  EKLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDA 241

Query: 1264 CEYTCVLLD 1272
              YTC+  D
Sbjct: 242  GVYTCLSPD 250



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 92/448 (20%), Positives = 163/448 (36%), Gaps = 45/448 (10%)

Query: 946  VILECQTSHTVS-TKWYHNKKEISGMDHRE----IIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            ++LE Q SH     KWY + +++    H      I+  G             D G   C 
Sbjct: 4    LVLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVCD 63

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
                   T + V       + K +     EV+E D   L  +++ ETA   W++DG+++ 
Sbjct: 64   AASDRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLL 123

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117
                +      G  R L I+   + D G + C   D+     + V E P   + + + ++
Sbjct: 124  -SGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEERE 182

Query: 1118 ---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
               V +G  A     ++K  A V W         S   QL  DG+   L + +   +DAG
Sbjct: 183  KLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAG 242

Query: 1175 EYSC------------------------EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210
             Y+C                              CT +    E  + F   L + +    
Sbjct: 243  VYTCLSPDDQMQFDISVRGEHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSD-VRARR 301

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                 L  E+     DV W K   V+E   +  +    ++R+L++     +D  EY C  
Sbjct: 302  GETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCES 361

Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND---EWIVNSKI 1327
             D ++   L V+V      I + +    +  G D T    ++    P D    W ++ + 
Sbjct: 362  NDDRTLATLTVQVRRVVEIIAELQ-SLMVLEGDDAT----FKCMVSPEDVVVTWQLDGRP 416

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +   +  + +      SLT++  + +DA
Sbjct: 417  VVPSERLQVARSGLCHSLTVRGCQPSDA 444



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 10/240 (4%)

Query: 1127 EIELTKGDALVRWFKDGSEIQFSNH----IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            E++L+     V+W+KDG ++Q + H    + +   G  ++L        D+G Y C+  +
Sbjct: 7    EVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVCDAAS 66

Query: 1183 SKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240
             +    + V   ++    +      + V       L  ++  ET    W K   ++    
Sbjct: 67   DRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGG 126

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYR 1298
            +  + S+   R+L I++    D   + C   D +   T  +K   V F  K  + E+   
Sbjct: 127  RLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLV 186

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            ++ GS V   V  +   Q +  W+   ++    +  +   D +  SL +  V   DAG+Y
Sbjct: 187  LEGGSAVLSAVVSKE--QADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAGVY 244



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           Q    +FV KLR     +   V  E +V  +   ++ W +Q  +++P   + M  +    
Sbjct: 463 QEAQVLFVRKLRDVVAEEQQDVCLEVEVS-HEAAEVQWLKQGVLLQPGDKYLMR-ESGCR 520

Query: 566 ATLVIREVFPEDAGTFTC 583
            TL IR V P D GT+ C
Sbjct: 521 RTLTIRSVSPSDRGTYRC 538



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 18/179 (10%)

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDT----EKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
            D  L V++     +V WYK    ++DT    E+  +++    R L        D   Y C
Sbjct: 3    DLVLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVC 62

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPND-EWIVN 1324
                 +  T   VEV     +IV+ E       ++ G  VTL+   Q  P+    +W  +
Sbjct: 63   DAASDRMVTS--VEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVA--QLSPETAAAQWQKD 118

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
             +++          +  + SLTIK+VE  DAG +       C   D E+  T+  K +P
Sbjct: 119  GQMLLSGGRLLVCSEGPARSLTIKQVELGDAGTFL------CDAGDDEVYFTLHVKEAP 171


>UniRef50_UPI0000ECB822 Cluster: Obscurin-like protein 1 precursor.;
            n=4; Gallus gallus|Rep: Obscurin-like protein 1
            precursor. - Gallus gallus
          Length = 1173

 Score =  128 bits (308), Expect = 2e-27
 Identities = 159/722 (22%), Positives = 300/722 (41%), Gaps = 45/722 (6%)

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----SVILSAQVVGNPR 763
            + V AVN+ G +  P+             +   L+   VR GE    SV LSA V G   
Sbjct: 431  FRVCAVNKHGRSD-PVEFPGCVHLVPAVHLERGLQDARVRDGEDARFSVELSASVQGEWF 489

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
               T  ++ +  +    +  G  HS+ +++  ++++ G       +S      SA++ V+
Sbjct: 490  LNGTRLQSEESGR-FSVQHCGTEHSL-LIRSARLRESGARVTFVASS---VRDSAILHVQ 544

Query: 824  EPTEENAEPPLFINRFQEI--TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
            E       P   I+  +E   T      ++L  +++R  VP + WY++ E +   E++  
Sbjct: 545  EA------PVRIISSNEETPHTYMAGQRVELWCQLSRAEVP-VRWYKDGEEVEEGESLVL 597

Query: 882  NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
              +G    LV+     + D+G++ C      G  S    +T+    V  V   +++  T 
Sbjct: 598  EREGPRCRLVLPCAHPQ-DTGEFVC----DVGGDSAFYTITVAEPPVRIVGSNEEAPHTY 652

Query: 942  -EGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
              G+ V L CQ S   +  +WY + +E+   +   + ++G             D G   C
Sbjct: 653  MAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLERKGPQCRLVLPCACPQDTGEFVC 712

Query: 1000 IVKDQE---TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
             V       T T+   +  I       Q  E+      +LE E++   A V W +DGE +
Sbjct: 713  DVGGDSVFYTITVAAPQAHIAPVPEAQQLQELLAGLPLLLECEVSPAGAPVRWLKDGEAM 772

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116
             P ++    +  G  R+L+I      D G Y+C   D++ +  VTV E P  I++  +  
Sbjct: 773  VPSES-LGIQAEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIVSSNEET 831

Query: 1117 KVN--KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174
                  G +     +L++ +A VRW+KDG E++    + L  +G + +L +    L D G
Sbjct: 832  PHTYVAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQDTG 891

Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
            E+ C+ G++  +  + V EP +      R P  + V       L+ E+      V W ++
Sbjct: 892  EFVCDTGDAAVSYHVMVAEPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWARE 951

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292
               +E    + L  +   R L+I     +   +Y C   D   T    V+V + P +I++
Sbjct: 952  GVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYLCDAADDAVT--FTVQVSDPPVRILE 1009

Query: 1293 YEREYRIKRGSDV-TLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI--- 1347
             +     +R   +  L+++ Q +      +W  + + ++   H +   D +  +L I   
Sbjct: 1010 RDALPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEKDGQRRALVILGA 1069

Query: 1348 --KKVENTDAGIYKLRLENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEP 1404
                V   DAG+Y     ++    D+ + V  +++  +      +LE D ++   C   P
Sbjct: 1070 TGSNVAKEDAGVYTCLSPDDQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFK-CMVSP 1128

Query: 1405 EN 1406
            E+
Sbjct: 1129 ED 1130



 Score =  104 bits (250), Expect = 2e-20
 Identities = 155/717 (21%), Positives = 268/717 (37%), Gaps = 54/717 (7%)

Query: 573  VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632
            V P DAG + C A++ +  A +   L+VE   S   S+ T             A    G 
Sbjct: 29   VRPPDAGVYVCRARSGSKEALAAAVLLVEPRCSP--SDSTQPRRLRHACTDTWAPAPNGT 86

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P     + KA  V  G      C +   P+P+I W   G+ + P       I  D   Y 
Sbjct: 87   P-----RAKAFAVSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRR--HLIYEDREGY- 138

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             +LK+   +   +G Y   A N  G+    + L++    +   QV  PL+ + V + E  
Sbjct: 139  FILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQV-AEHRLRFQV--PLEDVEVAEREDA 195

Query: 753  ILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AEN 809
            +L  QV     PT  + ++   +P      +  G    +TI +  +  D+G+Y  +  + 
Sbjct: 196  VLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVRRLTI-RDARTDDDGIYLCQMKDR 254

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
               IAE S                L + R        +G        TR  V  I+W RN
Sbjct: 255  GRSIAEVSV-------------RGLIVKRLPRKLDVMEGENAAFCVETREAVEGISWTRN 301

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKV 928
               +  S        G    LV+ +V  E D+G    +   S G+S   +++ +  V++ 
Sbjct: 302  GLQLHESPRAVLKSFGRTHLLVLVHVTRE-DAG----IICFSVGESLTSSQLRVKCVKRD 356

Query: 929  TFVKHLQKSYETEEGKTVILE-C---QTSHTVSTKWYHNKKEISGMDHREIIQ---EGRX 981
                 +     TE+    +L  C      H   + +   ++E +G    + +     GR 
Sbjct: 357  PPGVPMAAQLSTEQSNAALLTWCPAPDVHHCPPSAYIVERREAAGGSWVQCLSTELPGRV 416

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK---ETIP--EFIRKLQDFEVKEKDVAIL 1036
                       D     C V     S  +        +P     R LQD  V++ + A  
Sbjct: 417  QVLGDSVPREADYCFRVCAVNKHGRSDPVEFPGCVHLVPAVHLERGLQDARVRDGEDARF 476

Query: 1037 EVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDE 1094
             VE+ S +    W  +G  ++ +++ ++  +  G    L IR+  + + G   + +    
Sbjct: 477  SVEL-SASVQGEWFLNGTRLQSEESGRFSVQHCGTEHSLLIRSARLRESGARVTFVASSV 535

Query: 1095 SCTAEVTVVELPPEIITRLQN--QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152
              +A + V E P  II+  +        G +     +L++ +  VRW+KDG E++    +
Sbjct: 536  RDSAILHVQEAPVRIISSNEETPHTYMAGQRVELWCQLSRAEVPVRWYKDGEEVEEGESL 595

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF-ILVPAN 1211
             L  +G + +L +      D GE+ C+VG       +TV EP +       E      A 
Sbjct: 596  VLEREGPRCRLVLPCAHPQDTGEFVCDVGGDSAFYTITVAEPPVRIVGSNEEAPHTYMAG 655

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
                L  ++      V WYK    +E+ E   L     +  L++      D  E+ C
Sbjct: 656  QRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLERKGPQCRLVLPCACPQDTGEFVC 712



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 94/414 (22%), Positives = 169/414 (40%), Gaps = 34/414 (8%)

Query: 749  GESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV-KDEGVYT 804
            G  ++L  +V     P + W K+ +   P ++L  +++G    + I  P  V  D G YT
Sbjct: 747  GLPLLLECEVSPAGAP-VRWLKDGEAMVPSESLGIQAEGCWRRLHI--PTAVPSDSGTYT 803

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI--TVKEKGTIKLVARVTRNPVP 862
              A    G    S V+TV E       P   ++  +E   T      ++L  +++R   P
Sbjct: 804  CDA----GDDTVSFVVTVSEA------PVRIVSSNEETPHTYVAGQRVELWCQLSRAEAP 853

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             + WY++ E +   E++    +G    LV+     + D+G++ C   ++A   S+   V 
Sbjct: 854  -VRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQ-DTGEFVCDTGDAA--VSYHVMVA 909

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
                K+   +      +   G+TV L C+ S       W      +       + +EG  
Sbjct: 910  EPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAH 969

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK--LQDFE-VKEKDVAILEV 1038
                         G   C   D   +  + V +     + +  L      +  +  +LEV
Sbjct: 970  RRLLIPAARAEHAGKYLCDAADDAVTFTVQVSDPPVRILERDALPTCRRCRAMEDLVLEV 1029

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI-----RNTSVHDEGEYSCILRD 1093
            +++    +V W +DGE ++   +    EK G  R L I      N +  D G Y+C+  D
Sbjct: 1030 QLSHAHGEVKWYKDGEKLQDTGH-VRLEKDGQRRALVILGATGSNVAKEDAGVYTCLSPD 1088

Query: 1094 ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI 1146
            +    +++V V    EII  LQ+  V +G+ ATF+  ++  D +V W  DG  +
Sbjct: 1089 DQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPV 1142



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 97/432 (22%), Positives = 170/432 (39%), Gaps = 36/432 (8%)

Query: 640  PKAQYVDE---GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            P+AQ + E   G  +LLEC +     P + WL  GE +VP E++ +  E         L 
Sbjct: 736  PEAQQLQELLAGLPLLLECEVSPAGAP-VRWLKDGEAMVPSESLGIQAEGCWRR----LH 790

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756
            I        GTYT  A    G+ ++  V+ +           E      V  G+ V L  
Sbjct: 791  IPTAVPSDSGTYTCDA----GDDTVSFVVTVSEAPVRIVSSNEETPHTYVA-GQRVELWC 845

Query: 757  QVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            Q+     P + W K+ + V+   +L  + +G    + +L   +++D G +        G 
Sbjct: 846  QLSRAEAP-VRWYKDGEEVEEGESLVLEREGPRCRL-VLPCARLQDTGEFVCDT----GD 899

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
            A  S  + V EP  +  +P         + V    T+ L   ++R   P + W R    +
Sbjct: 900  AAVSYHVMVAEPPVKILQPQ---RPPPVVKVSPGETVTLSCELSRPDAP-VCWAREGVRL 955

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
                +     +G +  L+I    +E  +G Y C A++ A   +   +V+    ++     
Sbjct: 956  EAGGSWVLEEEGAHRRLLIPAARAE-HAGKYLCDAADDA--VTFTVQVSDPPVRILERDA 1012

Query: 934  LQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX-----XXXX 987
            L         + ++LE Q SH     KWY + +++    H  + ++G+            
Sbjct: 1013 LPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEKDGQRRALVILGATGS 1072

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046
                 D GV  C+  D +    + V+   + E I +LQ   V E D A  +  ++ E   
Sbjct: 1073 NVAKEDAGVYTCLSPDDQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVV 1132

Query: 1047 VVWERDGEIIKP 1058
            V W+ DG  + P
Sbjct: 1133 VTWQLDGRPVVP 1144



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 102/513 (19%), Positives = 192/513 (37%), Gaps = 32/513 (6%)

Query: 1118 VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK-LKIYDCDLDDAGE 1175
            V+ G  A F   +T K    + W KDG  +       +  D +    LK+  C   D G 
Sbjct: 94   VSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGL 153

Query: 1176 YSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            Y C   N+    +    L V E  + F + L E + V    DA L  ++P  ++   W+ 
Sbjct: 154  YVCTASNTAGQTLSAVQLQVAEHRLRFQVPL-EDVEVAEREDAVLECQVPLGSIPTAWFL 212

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVE--VVEFPP 1288
            +   ++ + K+ +      R L IR    DD   Y C + D  +S  ++ V   +V+  P
Sbjct: 213  EDRELQPSHKYVMEECGVVRRLTIRDARTDDDGIYLCQMKDRGRSIAEVSVRGLIVKRLP 272

Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348
            + +D      +  G +    V+ +   +    W  N   + +          ++  L + 
Sbjct: 273  RKLD------VMEGENAAFCVETREAVE-GISWTRNGLQLHESPRAVLKSFGRTHLLVLV 325

Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG 1408
             V   DAGI    +  +   + + +     D P  P    +    S++  + W    +  
Sbjct: 326  HVTREDAGIICFSVGESLTSSQLRVKCVKRDPPGVPMAAQLSTEQSNAALLTWCPAPDVH 385

Query: 1409 NSTIIYYVVEYQEIDTTEWI---SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            +     Y+VE +E     W+   S +   + Q    ++   + Y FR  AVN+   SD  
Sbjct: 386  HCPPSAYIVERREAAGGSWVQCLSTELPGRVQVLGDSVPREADYCFRVCAVNKHGRSDPV 445

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
            E      ++    +     E+ L++      ED   +       Q +  W+ +G +L++ 
Sbjct: 446  EFPGCVHLVPAVHL-----ERGLQDARVRDGEDARFSVELSASVQGE--WFLNGTRLQSE 498

Query: 1526 KA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIK 1581
            ++   + ++                           V  S ++ +Q+ PV I  SNE+  
Sbjct: 499  ESGRFSVQHCGTEHSLLIRSARLRESGARVTFVASSVRDSAILHVQEAPVRIISSNEETP 558

Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
              +  G    +   +     P V WYK+G ++E
Sbjct: 559  HTYMAGQRVELWCQLSRAEVP-VRWYKDGEEVE 590



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 51/247 (20%), Positives = 107/247 (43%), Gaps = 6/247 (2%)

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVT 1101
            +++W++DG+ + P +    +E R     L +      D+G Y C   + +       ++ 
Sbjct: 113  EIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQ 172

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            V E        L++ +V +   A  E ++  G     WF +  E+Q S+   +   G  +
Sbjct: 173  VAEHRLRFQVPLEDVEVAEREDAVLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVR 232

Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221
            +L I D   DD G Y C++   +  +I  V    +    RLP  + V    +A   VE  
Sbjct: 233  RLTIRDARTDDDGIYLCQM-KDRGRSIAEVSVRGL-IVKRLPRKLDVMEGENAAFCVETR 290

Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
            +    ++W +    + ++ +  L S  +   L++   T +D       + ++ ++++L+V
Sbjct: 291  EAVEGISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRV 350

Query: 1282 EVVEFPP 1288
            + V+  P
Sbjct: 351  KCVKRDP 357



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 24/77 (31%), Positives = 35/77 (45%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G   +F C V G P+P+I W +    + P +   +Y D +    L +    P D G + C
Sbjct: 97  GKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVC 156

Query: 584 VAKNAAGFASSTTELIV 600
            A N AG   S  +L V
Sbjct: 157 TASNTAGQTLSAVQLQV 173



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G P PE+IW K+G  +   + + I   +E   ++++   +      Y   ASNTAG +
Sbjct: 106  VTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQT 165

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWKPPL 1691
               V L+V +   + + P+   E++ RE   +E + PL
Sbjct: 166  LSAVQLQVAEHRLRFQVPLEDVEVAEREDAVLECQVPL 203



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/152 (19%), Positives = 58/152 (38%), Gaps = 2/152 (1%)

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            + W +NG +L       + +  +T ++ +  + R  +         +  +S + V     
Sbjct: 296  ISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRVKCVKR 355

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
            D P  P    +  E S  ++ + W P  D      + Y +E+ E     W++    +   
Sbjct: 356  DPPGVPMAAQLSTEQSNAAL-LTWCPAPDVHHCPPSAYIVERREAAGGSWVQCLSTELPG 414

Query: 1724 ETYCI-QKLNENCEYMFRVIAQNPVGFSEALE 1754
                +   +    +Y FRV A N  G S+ +E
Sbjct: 415  RVQVLGDSVPREADYCFRVCAVNKHGRSDPVE 446



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 39/195 (20%), Positives = 75/195 (38%), Gaps = 3/195 (1%)

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
            +T  +   + E  ++  +  +   + T    + +EL C       P V WY+DG++++  
Sbjct: 809  DTVSFVVTVSEAPVRIVSSNEETPH-TYVAGQRVELWCQLSRAEAP-VRWYKDGEEVEEG 866

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK 1585
            ++    R                      D G+   S  V + + PV  +  +      K
Sbjct: 867  ESLVLEREGPRCRLVLPCARLQDTGEFVCDTGDAAVSYHVMVAEPPVKILQPQRPPPVVK 926

Query: 1586 VGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            V     VT   E   P   V W + G +LE    + +  +     + I   +  H+ KY 
Sbjct: 927  VSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYL 986

Query: 1645 IEASNTAGTSSVEVT 1659
             +A++ A T +V+V+
Sbjct: 987  CDAADDAVTFTVQVS 1001


>UniRef50_Q4RH47 Cluster: Chromosome undetermined SCAF15069, whole
            genome shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF15069, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1485

 Score =  128 bits (308), Expect = 2e-27
 Identities = 103/401 (25%), Positives = 183/401 (45%), Gaps = 22/401 (5%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P +P   V++ E ++  V + WKPP+  G  E   Y IEK     + W +V +    V++
Sbjct: 475  PGEPTD-VVVTEATKSYVVLAWKPPVQRGH-EGVMYYIEKCVSGTDSWQRV-NTGMPVKS 531

Query: 1726 --YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
              + +  L E   Y FRV   N  G  EA + +  I +   LD+P+            N 
Sbjct: 532  PRFAMFDLAEGKTYSFRVRCCNSAGVGEASVSTGEITVGDVLDLPAAPGNPVVIRNT-NT 590

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQFRI 1839
            SV +TW  S+      ++ Y +E  Q G   W           R     L+    Y FR+
Sbjct: 591  SVVVTWGASKDV--KHLVGYYIECSQTGTDIWMACNNKPVKETRFVCHGLTNGANYVFRV 648

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             A N  G S      + + +   ++ P +P    + E+    + L WT P ++GG+ +  
Sbjct: 649  KAVNAAGYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMVLGWTAPANDGGATVRG 708

Query: 1900 YIIEFKTVKGK---SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            Y ++++TVKG     W ++     +   +  EN+KE     F++ A N  G+S  +   +
Sbjct: 709  YFVDYRTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGSVPSA 768

Query: 1957 VRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT--KTM 2012
            V   K  T+ + P AP+++R+  V    V+  W  P + G  P+ GY + +++ +  +  
Sbjct: 769  VLECKEWTI-TLPGAPVDLRVLEVRDTSVVLLWEPPAFCGRTPVNGYYVDLKEASAGEDG 827

Query: 2013 WMEVGKVDVNTLKF-NIRDLSENHTYMIRIYARNEIGLSEP 2052
            W  V +  VN +K+  ++ L  + +Y+ R+ A+N  G+ +P
Sbjct: 828  WKAVHE-KVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKP 867



 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 80/335 (23%), Positives = 134/335 (40%), Gaps = 20/335 (5%)

Query: 1634 ELKRSHSSKYTIEASNTAGT-----SSVEVTL-KVYDKPSKPEGPVIMREISRESVTIEW 1687
            +L    +  + +   N+AG      S+ E+T+  V D P+ P  PV++R  +  SV + W
Sbjct: 538  DLAEGKTYSFRVRCCNSAGVGEASVSTGEITVGDVLDLPAAPGNPVVIRN-TNTSVVVTW 596

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
                D     L  Y IE  +   + W+   +       +    L     Y+FRV A N  
Sbjct: 597  GASKDVK--HLVGYYIECSQTGTDIWMACNNKPVKETRFVCHGLTNGANYVFRVKAVNAA 654

Query: 1748 GFSEAL-ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI----IDY 1802
            G+S +  +SE +V+K A+ VP           + +  V + W     +GG+ +    +DY
Sbjct: 655  GYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMV-LGWTAPANDGGATVRGYFVDY 713

Query: 1803 KVEIKQEGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
            +        KW             + + L  N  Y+F++ A N  G S        +   
Sbjct: 714  RTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGSVPSAVLECK 773

Query: 1861 K-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG--KSWTKIVT 1917
            + T+T P  P +  V E    SV L W  P   G +P+  Y ++ K        W  +  
Sbjct: 774  EWTITLPGAPVDLRVLEVRDTSVVLLWEPPAFCGRTPVNGYYVDLKEASAGEDGWKAVHE 833

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
                V    ++ +K     +FR+ A+N  GV  P+
Sbjct: 834  KVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKPS 868



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 20/214 (9%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F  KP+ Q V EG  + L C +   P+P IAW +K   ++  +       ++     
Sbjct: 75  PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAW-YKNNVLIDAKAHPEKYTAESTYNM 133

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP----------PQVIEPLK 742
             L+I N        Y+V A+N +GEAS    + +K  +++             + +  +
Sbjct: 134 HSLEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193

Query: 743 SMIVRQGESVILSAQV-----VGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794
                +GE+V L   V     V N +P + W +++   KP K + T   G+   +T++  
Sbjct: 194 VAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLVHL 253

Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            K +DEG+YTL+     G    SA + V +   E
Sbjct: 254 NK-EDEGMYTLRVNTKSGYDSYSAYVFVRDADVE 286



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 20/208 (9%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT----H 787
           PP+ I   +   V +G+++ L   V G P+P I W KNN  +  KA P K   ++    H
Sbjct: 75  PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMH 134

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN--AEPPL-----FINRFQ 840
           S+ I K     D   Y++ A N +G A   A I V+   E+   AE  +       ++F+
Sbjct: 135 SLEI-KNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193

Query: 841 EITVKEKGTIKLVARV-----TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
                E  T+ L   V      +N  P + WYR++  + PS+ +  ++ GE   L + ++
Sbjct: 194 VAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLVHL 253

Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTI 923
           + E D G Y    +  +G  S+ A V +
Sbjct: 254 NKE-DEGMYTLRVNTKSGYDSYSAYVFV 280



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 49/240 (20%), Positives = 95/240 (39%), Gaps = 28/240 (11%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--NVAT 567
           P F+ K R +   +G T+   C V G+P+P+I W++   +I      + Y  +   N+ +
Sbjct: 76  PEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMHS 135

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
           L I+     D   ++  A N  G AS    ++V+    D                   A+
Sbjct: 136 LEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQED----------------AFCAE 179

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-----EPDIAWLFKGEEIVPDENISV 682
                  T + K +  +  EG  + L C ++  P     +P++ W      + P + +  
Sbjct: 180 HGVTFLTTITDKFEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQT 239

Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPL 741
               +     ++L + ++ K  EG YT+    + G  S    + ++  + E   V + PL
Sbjct: 240 HWSGER----AILTLVHLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVEVEGVPVAPL 295



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 61/318 (19%), Positives = 121/318 (38%), Gaps = 40/318 (12%)

Query: 1426 EWISVKNI----TKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQ 1480
            ++++++N+     +    ++  K   + R R  A   E+      E  E+ + +    + 
Sbjct: 14   QYVAMRNLFVREAREAVDVKVQKKTRTTRMRESAERVELSKDGLDEWVEFRRKMNPDSLT 73

Query: 1481 SPT--VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-----DGK---KLKTAKATYE 1530
             P   + KP +  T    + + L C   G P+PK+ WY+     D K   +  TA++TY 
Sbjct: 74   HPPEFIIKP-RGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTY- 131

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDE 1589
            N                Y   A N  GE      + +++        E  +     + D+
Sbjct: 132  NMHSLEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDK 191

Query: 1590 WLVTAVIEG----------IPP------PEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
            + V    EG          + P      PEV+WY++   L+  K        + +++ + 
Sbjct: 192  FEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLV 251

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG------PVIMREISRESVTIEW 1687
             L +     YT+  +  +G  S    + V D   + EG       V   + +++ V + W
Sbjct: 252  HLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVEVEGVPVAPLDVCCHDANKDYVVVTW 311

Query: 1688 KPPLDDGGLELTKYAIEK 1705
            K P  +G   +  Y +++
Sbjct: 312  KQPAVEGSSSILGYYVDR 329



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 24/95 (25%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--IT 1434
            +LD P+ PG P ++   ++S+ + W   ++  +  ++ Y +E  +  T  W++  N  + 
Sbjct: 572  VLDLPAAPGNPVVIRNTNTSVVVTWGASKDVKH--LVGYYIECSQTGTDIWMACNNKPVK 629

Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            +T+     L   ++Y FR  AVN    S +S  +E
Sbjct: 630  ETRFVCHGLTNGANYVFRVKAVNAAGYSPSSPDSE 664



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  + G P PEV W KN  +L +D  Y +T +  K + I I  +  + S KY +   N 
Sbjct: 1407 LTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGKYALLVKNK 1466

Query: 1651 AGTSSVEVTLKVYDKPSKPE 1670
             GT +   T+ VY+ P + E
Sbjct: 1467 YGTEAGAFTVSVYN-PEEEE 1485



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 73/323 (22%), Positives = 124/323 (38%), Gaps = 30/323 (9%)

Query: 1357 IYKLRLENNCGHADVEMN---VTILDKPSPPGKPN---ILEIDSSSINICWDEPENTGNS 1410
            +++++  N  G++    +   V +    S PGKP    +LE     + + W  P N G +
Sbjct: 645  VFRVKAVNAAGYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMVLGWTAPANDGGA 704

Query: 1411 TIIYYVVEYQEID---TTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            T+  Y V+Y+ +      +W  + +  +T T    +NLK N  Y F+  A+N   +S  S
Sbjct: 705  TVRGYFVDYRTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGS 764

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLK 1523
              +   +  KE  I  P     L+ +       + L     F G   P   +Y D K+  
Sbjct: 765  VPSAVLE-CKEWTITLPGAPVDLRVLEVRDTSVVLLWEPPAFCG-RTPVNGYYVDLKEAS 822

Query: 1524 TA----KATYE--NRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
                  KA +E  NR                ++  A N  G  + S  +G    PV+  +
Sbjct: 823  AGEDGWKAVHEKVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKPSATLG----PVLAQT 878

Query: 1577 NEDIKQKH-KVGDEWLVTAVI---EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
                K+ +  V D+ +++ V    E     E IW KN   + +     I  +   S    
Sbjct: 879  RAGTKEIYVDVDDDGVISMVFECSEMTESSEFIWSKNYQAITDTSRVTIVNERGRSRAIF 938

Query: 1633 KELKRSHSSKYTIEASNTAGTSS 1655
                      ++  A+NT G SS
Sbjct: 939  NNPSLEDLGTFSCVATNTDGMSS 961



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 6/103 (5%)

Query: 731  EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGD 785
            E+   +VI  L  ++ +++G+S+ L+  V G+P P ++W KN K + +      T   G 
Sbjct: 1383 ERNRARVIGGLPDVVAIQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGK 1442

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
              SITI    +  D G Y L  +N  G    +  ++V  P EE
Sbjct: 1443 FASITIAAVTEA-DSGKYALLVKNKYGTEAGAFTVSVYNPEEE 1484



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 49/222 (22%), Positives = 81/222 (36%), Gaps = 30/222 (13%)

Query: 1227 VTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            + WYK   +I+     EK+T  S     +L I+ C+  D  +Y+   L+ K        +
Sbjct: 107  IAWYKNNVLIDAKAHPEKYTAESTYNMHSLEIKNCSFTDTAQYSVSALNVKGEASYVATI 166

Query: 1284 V---------------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP-----QPNDEWIV 1323
            V                F   I D         G  V+L      +P     QP   W  
Sbjct: 167  VVKRYQEDAFCAEHGVTFLTTITDKFEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYR 226

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--- 1380
            +S  +K  K  +     + A LT+  +   D G+Y LR+    G+      V + D    
Sbjct: 227  DSVPLKPSKWVQTHWSGERAILTLVHLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVE 286

Query: 1381 ----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
                P  P      + +   + + W +P   G+S+I+ Y V+
Sbjct: 287  VEGVPVAPLDVCCHDANKDYVVVTWKQPAVEGSSSILGYYVD 328



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 16/134 (11%)

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDGENI 888
           PP FI + +  TV E  T+ L   V   P P I WY+NN +I      E  T        
Sbjct: 75  PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMH 134

Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHLQKSYE 939
            L I N  S  D+  Y   A N  G++S+ A + +             VTF+  +   +E
Sbjct: 135 SLEIKNC-SFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193

Query: 940 T---EEGKTVILEC 950
                EG+TV L C
Sbjct: 194 VAFGTEGETVSLGC 207



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 11/152 (7%)

Query: 789 ITILKPKKVKDEG--VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
           +  LK K +K +   V+ ++A+N  G+ + SA +             ++++      V +
Sbjct: 838 VKYLKVKGLKPDTSYVFRVRAQNLTGVGKPSATLGPVLAQTRAGTKEIYVD------VDD 891

Query: 847 KGTIKLVARVTRNPVPS-ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
            G I +V   +     S   W +N + I+ +  +T   +      +  N   E D G + 
Sbjct: 892 DGVISMVFECSEMTESSEFIWSKNYQAITDTSRVTIVNERGRSRAIFNNPSLE-DLGTFS 950

Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
           CVA+N+ G SS           ++FV HLQ S
Sbjct: 951 CVATNTDGMSSSYTLTEEGKSHLSFV-HLQNS 981



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEID 900
            + ++E  ++ L   V  +PVP ++W +N  E++S          G+   + I  V +E D
Sbjct: 1397 VAIQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAV-TEAD 1455

Query: 901  SGDYKCVASNSAGKSSHGARVTI 923
            SG Y  +  N  G  +    V++
Sbjct: 1456 SGKYALLVKNKYGTEAGAFTVSV 1478



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI 1357
            I+ G  + L  +    P P   W  N K +    H K + +  K AS+TI  V   D+G 
Sbjct: 1399 IQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGK 1458

Query: 1358 YKLRLENNCG 1367
            Y L ++N  G
Sbjct: 1459 YALLVKNKYG 1468



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 17/81 (20%), Positives = 36/81 (44%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G ++     V G P P+++W +    +     +++ Y+    A++ I  V   D+G + 
Sbjct: 1401 EGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGKYA 1460

Query: 583  CVAKNAAGFASSTTELIVEAP 603
             + KN  G  +    + V  P
Sbjct: 1461 LLVKNKYGTEAGAFTVSVYNP 1481


>UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladin;
           n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
           "Palladin - Takifugu rubripes
          Length = 986

 Score =  127 bits (307), Expect = 3e-27
 Identities = 97/364 (26%), Positives = 165/364 (45%), Gaps = 23/364 (6%)

Query: 478 NNYTQYLQKKLNEKIDKLPVFEKPTS---EEQSM----APIFVEKLRPKHTPDGSTVQFE 530
           +++ Q L  ++  ++++ PV E       +E S     AP F  KL+     +G  V F 
Sbjct: 591 SSFEQRLISEIEFRLERSPVEESDDDVQHDEDSAGRGAAPSFDRKLKHYKVFEGMPVTFS 650

Query: 531 CQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           C+V G P+P++ WF+    I K S+ +++  D D   +L       +D G +T +A N  
Sbjct: 651 CKVNGDPKPKVYWFKDGKQISKRSEHYRISRDADGTCSLHTVAASLDDDGNYTIMASNPE 710

Query: 590 GFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQY 644
           G  S T  ++V+A      S+ ++             D  + I      P F + P    
Sbjct: 711 GRVSCTGRMMVQAVNQRGRSKRSMPGHMRRSRSRDSGDENDNIQERHFRPHFLQAPGDLI 770

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKF 703
           V EG    ++C++  +P PD+ W   G+ I PD    + + E+ +H     L I  V   
Sbjct: 771 VQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHS----LVIEPVTSR 826

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
             G YT +A NR G+ S  + L +   E  + P  +E L++  V +G  V L  +V G P
Sbjct: 827 DAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLECRVSGVP 886

Query: 763 RPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P I W + N+ +      +    D   +   I++P   +D G YT+ A+N  GI  ++A
Sbjct: 887 YPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKNEAGIVSSTA 946

Query: 819 VITV 822
            + +
Sbjct: 947 RLDI 950



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 2/111 (1%)

Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
           P+S+E    P F++KL+ +   +GS +  ECQV G P+P + WF +   +  S D Q+  
Sbjct: 5   PSSQEPLSPPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQI-S 63

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610
            D  + TLVI E F +D G +TC+A N  G  +++ E+ +E A  SD   E
Sbjct: 64  SDGVLHTLVISEAFEDDTGRYTCIASNCLGADNTSAEVYIEGASSSDSDGE 114



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 80/330 (24%), Positives = 146/330 (44%), Gaps = 37/330 (11%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESD-- 687
           G  P+F +K K   V EG  +   C++   P+P + W   G++I    E+  ++ ++D  
Sbjct: 627 GAAPSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQISKRSEHYRISRDADGT 686

Query: 688 --MHMYCSVL----KITNVKKFQEGTYT------VVAVNREGEA--SLPIVLKIK----T 729
             +H   + L      T +    EG  +      V AVN+ G +  S+P  ++      +
Sbjct: 687 CSLHTVAASLDDDGNYTIMASNPEGRVSCTGRMMVQAVNQRGRSKRSMPGHMRRSRSRDS 746

Query: 730 GEKEP--------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781
           G++          P  ++    +IV++G    +  +V G P P + W  N + ++     
Sbjct: 747 GDENDNIQERHFRPHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAH 806

Query: 782 S----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
                +   HS+ +++P   +D G+YT  A N  G  + S  + +    +E  + P F+ 
Sbjct: 807 KMLVRENGVHSL-VIEPVTSRDAGIYTCIASNRAG--QNSFNLELIVAAKEMHKVPTFME 863

Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVD 896
           + Q  +V E   ++L  RV+  P P I W R NE ++  ++ I+ + D      +I    
Sbjct: 864 KLQNTSVAEGHPVRLECRVSGVPYPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPA 923

Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            + D+G Y   A N AG  S  AR+ I  +
Sbjct: 924 LKEDAGWYTVSAKNEAGIVSSTARLDIHTQ 953



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 8/101 (7%)

Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DDDNVATL 568
           L+     +G  V  E +V G P  Q+ WFRQ   I  S DF++         + + + TL
Sbjct: 172 LQDVQASEGQVVVLESRVRGSPPLQVRWFRQGEEILDSPDFRILQKKPRSAAESEEICTL 231

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
           VI E FPED G F C   N  G  +ST  L V A  S HG+
Sbjct: 232 VIAEAFPEDGGLFCCTVSNPYGSKNSTAHLAVTAGES-HGN 271



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 1/99 (1%)

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
           ++E   PP F+ + +   V E   I L  +VT NP P + W+     +  S  I  + DG
Sbjct: 7   SQEPLSPPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDG 66

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
               LVI+    E D+G Y C+ASN  G  +  A V I+
Sbjct: 67  VLHTLVISEA-FEDDTGRYTCIASNCLGADNTSAEVYIE 104



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 5/125 (4%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
           P F+    ++ V+E    ++  +V+  P P + W  N + I P            +  ++
Sbjct: 760 PHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLV 819

Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKV-TFVKHLQKSYETEEGKTVIL 948
               +  D+G Y C+ASN AG++S    + +   ++ KV TF++ LQ +    EG  V L
Sbjct: 820 IEPVTSRDAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNT-SVAEGHPVRL 878

Query: 949 ECQTS 953
           EC+ S
Sbjct: 879 ECRVS 883



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 4/101 (3%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSIT 790
           PP  ++ LKS  V +G  + L  QV GNP+P + W    + +   P     SDG  H++ 
Sbjct: 13  PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLHTLV 72

Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           I +  +  D G YT  A N  G   TSA + +E  +  +++
Sbjct: 73  ISEAFE-DDTGRYTCIASNCLGADNTSAEVYIEGASSSDSD 112



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 1/78 (1%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP  + +L++Q+V +G+    E ++T     LVRWF +G E+  S  IQ++ DG    L 
Sbjct: 13   PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLHTLV 72

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            I +   DD G Y+C   N
Sbjct: 73   ISEAFEDDTGRYTCIASN 90



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 4/82 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F +K K+Q V EGS I LEC++   P+P + W  +G E+    +I ++ +  +H   
Sbjct: 13  PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLH--- 69

Query: 693 SVLKITNVKKFQEGTYTVVAVN 714
             L I+   +   G YT +A N
Sbjct: 70  -TLVISEAFEDDTGRYTCIASN 90



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            + G+P P++IW  NG  +  D  + +  +E     + I+ +    +  YT  ASN AG +
Sbjct: 783  VSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLVIEPVTSRDAGIYTCIASNRAGQN 842

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESV 1683
            S  + L V  K    + P  M ++   SV
Sbjct: 843  SFNLELIVAAK-EMHKVPTFMEKLQNTSV 870



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 39/178 (21%), Positives = 76/178 (42%), Gaps = 12/178 (6%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D  V+E  +  ++ +++   T D++W+ +G+ I+P        +   +  L 
Sbjct: 760  PHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLV 819

Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y+CI  +     S   E+ V    +   P  + +LQN  V +G+    E
Sbjct: 820  IEPVTSRDAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLE 879

Query: 1128 IELTKGD-ALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDL-DDAGEYSCEVGN 1182
              ++      + W ++   + Q ++ I +  D       I    L +DAG Y+    N
Sbjct: 880  CRVSGVPYPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKN 937



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           + E+   +  +E +      P F  + +   V E   +    +V  +P P + W+++ + 
Sbjct: 610 VEESDDDVQHDEDSAGRGAAPSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQ 669

Query: 873 ISP-SE--TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           IS  SE   I+++ DG  ++  V  ++D   D G+Y  +ASN  G+ S   R+ +
Sbjct: 670 ISKRSEHYRISRDADGTCSLHTVAASLD---DDGNYTIMASNPEGRVSCTGRMMV 721



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 34/182 (18%), Positives = 67/182 (36%), Gaps = 10/182 (5%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXXXXXYKCIAFND 1555
            + C   G+P P + W  +G+ ++   A      EN                 Y CIA N 
Sbjct: 779  MDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLVIEPVTSRDAGIYTCIASNR 838

Query: 1556 HGE--VETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             G+       +V  ++   +    E ++      G    +   + G+P P++ W +    
Sbjct: 839  AGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLECRVSGVPYPQIFWKRENES 898

Query: 1613 LENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
            L  + +     ++    +   I+   +  +  YT+ A N AG  S    L ++ +  +P 
Sbjct: 899  LTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKNEAGIVSSTARLDIHTQWQQPN 958

Query: 1671 GP 1672
             P
Sbjct: 959  LP 960



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 14/49 (28%), Positives = 26/49 (53%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529
            +P+ ++ LK+        +  +C   G P+PKV W++DGK++      Y
Sbjct: 629  APSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQISKRSEHY 677



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 9/94 (9%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQ-K 1162
            P    +L++ KV +G   TF  ++  GD    V WFKDG +I + S H +++ D      
Sbjct: 630  PSFDRKLKHYKVFEGMPVTFSCKVN-GDPKPKVYWFKDGKQISKRSEHYRISRDADGTCS 688

Query: 1163 LKIYDCDLDDAGEYSCEVGNSK----CTAILTVE 1192
            L      LDD G Y+    N +    CT  + V+
Sbjct: 689  LHTVAASLDDDGNYTIMASNPEGRVSCTGRMMVQ 722


>UniRef50_UPI000065E224 Cluster: eEF1A2 binding protein; n=2; Takifugu
            rubripes|Rep: eEF1A2 binding protein - Takifugu rubripes
          Length = 788

 Score =  127 bits (306), Expect = 4e-27
 Identities = 95/397 (23%), Positives = 156/397 (39%), Gaps = 15/397 (3%)

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K + G   +      G  P  + WY+ G +L  D    +      S + +   +R  + +
Sbjct: 103  KVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNNVKVEKCRSQSRLLLSRCQRKDTGE 162

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
              I+  N  G +     L V DKP+ P GP    E S   V  +W+PP DDGG  +T Y 
Sbjct: 163  IKIKLKNQHGVTEAISQLIVLDKPTPPLGPAETTESSATCVEFKWRPPKDDGGSPVTHYL 222

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            +E+ +   N W K+ ++   V  +    +    +Y +R+ A    G SE +E++ +   T
Sbjct: 223  MERQQVGRNTWKKLGEIP-GVPRHRDTDVEHGRKYCYRIWAVTAEGTSEMMETDEMQAGT 281

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822
             L  P            D + + I W      GGS I+ Y VE +++G            
Sbjct: 282  -LAFPGPPAPPAVVSAFD-DCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTINATDD 339

Query: 1823 XARIQKLSINTT-----YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
              + +K ++        Y+FR+ A N  G     +  + +       PP +     VSE+
Sbjct: 340  LIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSSPSEFVFARDPKKPPGKVVGLKVSET 399

Query: 1878 TSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935
            +     L WT+PE   G       Y I+ +      W++  T         +  +K  D 
Sbjct: 400  SYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCIEWSRCNTSPLITTSFSVRGLKHMDM 459

Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
               R++A N  G   P E     L+K+ T    P  P
Sbjct: 460  YWARVTATNDGGDGPPEE-----LQKYITAMPRPVRP 491



 Score =  101 bits (242), Expect = 2e-19
 Identities = 111/472 (23%), Positives = 177/472 (37%), Gaps = 25/472 (5%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            E +W+K G K+  D ++ I  +     + I + K  HS KY   A         E  + V
Sbjct: 29   EGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVADG----RKTEAMINV 84

Query: 1663 YDKPS-KPEGPVIMRE--ISRESVTIEWKPP-LDDGGLELTKYAI-EKHEPDNNRWIKVA 1717
             D P  +PE   +  E    R      +K P +    + +  Y   E+   DNN  +KV 
Sbjct: 85   KDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNN--VKV- 141

Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777
            +  R      + +         ++  +N  G +EA+ S+ IV    LD P+         
Sbjct: 142  EKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAI-SQLIV----LDKPTPPLGPAETT 196

Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXX-XXXXARIQKLSINTTY 1835
                  V   W P + +GGSP+  Y +E +Q G+  WK           R   +     Y
Sbjct: 197  ESSATCVEFKWRPPKDDGGSPVTHYLMERQQVGRNTWKKLGEIPGVPRHRDTDVEHGRKY 256

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             +RI+A    GTS      D++  G TL  P  P    V  +    + + W  P + GGS
Sbjct: 257  CYRIWAVTAEGTS-EMMETDEMQAG-TLAFPGPPAPPAVVSAFDDCINIAWEAPSNRGGS 314

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTE 1953
             I  Y++E +      W+ I      + E    + ++    E  FR++A N  GV   + 
Sbjct: 315  RILGYLVEKRKKGSNLWSTINATDDLIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSS 374

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA--PLLGYNIAIRDVTKT 2011
                   +    P      L++        + +W  PE   G      GY I +R     
Sbjct: 375  PSEFVFARDPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCI 434

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             W       + T  F++R L     Y  R+ A N+ G   P E  +    +P
Sbjct: 435  EWSRCNTSPLITTSFSVRGLKHMDMYWARVTATNDGGDGPPEELQKYITAMP 486



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 62/240 (25%), Positives = 112/240 (46%), Gaps = 16/240 (6%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +K G+ V +++ ++A P P+  W+ ++  + K + T  + DS S+ L I   E +D+G+Y
Sbjct: 504  VKAGNSVRIMMHFEASPLPDIMWLKDNVPVTK-RVTISNSDS-SSQLLIPSSERSDSGVY 561

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
             + ++N  G     + V + D P PPG   + E    ++ + W    +      ++Y V 
Sbjct: 562  SVLVKNLAGQETFSIEVRVTDDPRPPGPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVS 621

Query: 1419 YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET----TEYYK- 1472
              +     W +V + +   + ++ N      Y FR YA N++ IS  SE+    TE  K 
Sbjct: 622  KLDSTKGTWATVADRLFNNRFTVCNTMHGRVYHFRVYAKNDMGISPPSESPTWGTEKKKE 681

Query: 1473 -------VIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
                     ++  +Q P V   PLK        +  ++C   G P+P++TWYR+   L T
Sbjct: 682  RFALSTPAHRDRDMQCPPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNT 741



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 56/263 (21%), Positives = 113/263 (42%), Gaps = 4/263 (1%)

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
            N  A L  ++  E  +  W+K+   I   ++F +I +     LII KC E+   +Y  V 
Sbjct: 14   NEAAELMCKLSSEDCEGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVA 73

Query: 1271 LDAKSTTKLKV-EVVEFPPK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
               K+   + V +   F P+ +  +    +++ G +    + +        +W    + +
Sbjct: 74   DGRKTEAMINVKDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEEL 133

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKP 1387
                + K       + L + + +  D G  K++L+N  G  +    + +LDKP+PP G  
Sbjct: 134  LGDNNVKVEKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAISQLIVLDKPTPPLGPA 193

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTN 1446
               E  ++ +   W  P++ G S + +Y++E Q++    W  +  I    +    +++  
Sbjct: 194  ETTESSATCVEFKWRPPKDDGGSPVTHYLMERQQVGRNTWKKLGEIPGVPRHRDTDVEHG 253

Query: 1447 SSYRFRAYAVNEVDISDASETTE 1469
              Y +R +AV     S+  ET E
Sbjct: 254  RKYCYRIWAVTAEGTSEMMETDE 276



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 6/172 (3%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            K G+   +    E  P P+++W K+   +   K   I+  + +S + I   +RS S  Y+
Sbjct: 505  KAGNSVRIMMHFEASPLPDIMWLKDNVPVT--KRVTISNSDSSSQLLIPSSERSDSGVYS 562

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            +   N AG  +  + ++V D P +P GP+ + E    +VT+ W P  D+   +   Y + 
Sbjct: 563  VLVKNLAGQETFSIEVRVTDDP-RPPGPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVS 621

Query: 1705 KHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            K +     W  VAD +  +  T C         Y FRV A+N +G S   ES
Sbjct: 622  KLDSTKGTWATVADRLFNNRFTVC--NTMHGRVYHFRVYAKNDMGISPPSES 671



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 104/450 (23%), Positives = 168/450 (37%), Gaps = 35/450 (7%)

Query: 1625 EKTSVIRIKELKRSHSSKYT--IEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREI 1678
            E   V R ++    H  KY   I A    GTS +    E+       P  P  P ++   
Sbjct: 238  EIPGVPRHRDTDVEHGRKYCYRIWAVTAEGTSEMMETDEMQAGTLAFPGPPAPPAVVSAF 297

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV-ETYC-IQKLNENCE 1736
              + + I W+ P + GG  +  Y +EK +  +N W  +   D  + E  C ++ +    E
Sbjct: 298  D-DCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTINATDDLIKEKKCAVRDVVSGME 356

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNG 1795
            Y FRV A N  G  E       V       P                  +TW  P EK G
Sbjct: 357  YEFRVTAVNLSGVGECSSPSEFVFARDPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPG 416

Query: 1796 -GSPIIDYKVEIKQ-EGKKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851
                   Y ++++Q +  +W              ++ L     Y  R+ A N+ G   P 
Sbjct: 417  IQDEAKGYFIDVRQADCIEWSRCNTSPLITTSFSVRGLKHMDMYWARVTATNDGGDGPPE 476

Query: 1852 TSDDKITIGKTLTPPS----QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
                 IT       P     + ++F+V ++ +    +   E      SP+ + I+  K  
Sbjct: 477  ELQKYITAMPRPVRPKFTNHKMKSFMVVKAGNSVRIMMHFE-----ASPLPD-IMWLKD- 529

Query: 1908 KGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965
                 TK VT+  S    +  I + +  D  ++ +  +N  G    T S  VR+      
Sbjct: 530  -NVPVTKRVTISNSDSSSQLLIPSSERSDSGVYSVLVKNLAGQE--TFSIEVRVTDD--- 583

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP  P+E+       V  +W     +     L Y ++  D TK  W  V     N  +
Sbjct: 584  PRPP-GPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVSKLDSTKGTWATVADRLFNN-R 641

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            F + +      Y  R+YA+N++G+S P ES
Sbjct: 642  FTVCNTMHGRVYHFRVYAKNDMGISPPSES 671



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 4/103 (3%)

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
            EM    L  P PP  P ++      INI W+ P N G S I+ Y+VE ++  +  W ++ 
Sbjct: 276  EMQAGTLAFPGPPAPPAVVSAFDDCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTIN 335

Query: 1432 N----ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
                 I + + +++++ +   Y FR  AVN   + + S  +E+
Sbjct: 336  ATDDLIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSSPSEF 378



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 2/91 (2%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           PP  I PLK     +G    +S  V GNP+P ITW +N+  +         +T  +  L 
Sbjct: 698 PPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYISNTCGVCSLL 757

Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITV 822
             +V  KD G YT+ AE+++G AE S V++V
Sbjct: 758 ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 1/91 (1%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P+F+  L+  + P G      C V G P+P+ITW+R    +    ++ +  +   V +L+
Sbjct: 699 PVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYI-SNTCGVCSLL 757

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           I  V P+D G +T  A++  G A  +T L V
Sbjct: 758 ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 13/185 (7%)

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           V+E ++++  C+L +  + +  W  +G +I PD+   +  E  +H     L IT  K+  
Sbjct: 13  VNEAAELM--CKLSS-EDCEGVWFKEGRKIPPDDQFCIIREGAVHK----LIITKCKEEH 65

Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            G Y  VA  R+ EA + +    +   ++     EP+K   VR G++ +     +G    
Sbjct: 66  SGKYRFVADGRKTEAMINVKDPPRFRPEDVCVFTEPVK---VRAGQNAMFKMPFIGQEPI 122

Query: 765 TITWCKNNKPVKA-LPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAET-SAVIT 821
            I W +  + +      K +   + S  +L   + KD G   +K +N  G+ E  S +I 
Sbjct: 123 RIQWYREGEELLGDNNVKVEKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAISQLIV 182

Query: 822 VEEPT 826
           +++PT
Sbjct: 183 LDKPT 187



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 4/90 (4%)

Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
           M+V+ G SV +      +P P I W K+N PV    T S+ D+ S  ++   +  D GVY
Sbjct: 502 MVVKAGNSVRIMMHFEASPLPDIMWLKDNVPVTKRVTISNSDSSSQLLIPSSERSDSGVY 561

Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPP 833
           ++  +N  G  ET    ++E    ++  PP
Sbjct: 562 SVLVKNLAG-QET---FSIEVRVTDDPRPP 587



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 34/160 (21%), Positives = 58/160 (36%), Gaps = 8/160 (5%)

Query: 1379 DKPSPPGKPNILEIDSSSIN---ICWDEPENTGN--STIIYYVVEYQEIDTTEW--ISVK 1431
            D   PPGK   L++  +S     + W +PE           Y ++ ++ D  EW   +  
Sbjct: 383  DPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCIEWSRCNTS 442

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
             +  T  S++ LK    Y  R  A N+       E  +Y   +        T  K    +
Sbjct: 443  PLITTSFSVRGLKHMDMYWARVTATNDGGDGPPEELQKYITAMPRPVRPKFTNHKMKSFM 502

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
              +    + +   F   P P + W +D   + T + T  N
Sbjct: 503  VVKAGNSVRIMMHFEASPLPDIMWLKDNVPV-TKRVTISN 541



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 21/76 (27%), Positives = 32/76 (42%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E  ++  + G P P + WY+N   L  D  Y I+       + I  +      +YTI 
Sbjct: 713  GYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYISNTCGVCSLLILRVGPKDMGEYTIT 772

Query: 1647 ASNTAGTSSVEVTLKV 1662
            A +T G +     L V
Sbjct: 773  AESTQGRAECSTVLSV 788



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F    K     +G +  + C +   P+P I W      +  D N  +   S+    C
Sbjct: 698 PPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYI---SNTCGVC 754

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
           S+L I  V     G YT+ A + +G A    VL +
Sbjct: 755 SLL-ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 32/154 (20%), Positives = 61/154 (39%), Gaps = 4/154 (2%)

Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
            +L+  D    WFK+G +I   +   +  +G   KL I  C  + +G+Y       K  A+
Sbjct: 22   KLSSEDCEGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVADGRKTEAM 81

Query: 1189 LTVEEP---SINFTLRLPEFILVPANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKFTL 1244
            + V++P            E + V A  +A   +  I  E + + WY++   +       +
Sbjct: 82   INVKDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNNVKV 141

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278
                 +  L++ +C   D  E    L +    T+
Sbjct: 142  EKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTE 175



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 833 PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
           P F N   +  + VK   +++++     +P+P I W ++N  ++   TI+ N D  + +L
Sbjct: 491 PKFTNHKMKSFMVVKAGNSVRIMMHFEASPLPDIMWLKDNVPVTKRVTIS-NSDSSS-QL 548

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           +I + +   DSG Y  +  N AG+ +    V +
Sbjct: 549 LIPSSERS-DSGVYSVLVKNLAGQETFSIEVRV 580


>UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar to
           human palladin (KIAA0992),; n=3; Eutheria|Rep: Testis
           cDNA, clone: QtsA-19723, similar to human palladin
           (KIAA0992), - Macaca fascicularis (Crab eating macaque)
           (Cynomolgus monkey)
          Length = 452

 Score =  127 bits (306), Expect = 4e-27
 Identities = 97/336 (28%), Positives = 148/336 (44%), Gaps = 20/336 (5%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYD 561
           S E  MAP F  KL+     +G  V F C+V G P+P+I WF+    I P  D + +  D
Sbjct: 63  SVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 122

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-------PLSDHGSEMTVX 614
            D   +L       +D G +T +A N  G  S T  L+V+A       P S  G      
Sbjct: 123 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 182

Query: 615 XXXXXXXXXXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672
                       + ++     P F + P    V EG    ++C++  +P PD++W   G+
Sbjct: 183 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 242

Query: 673 EIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
            I PD    + + E+ +H     L I  V     G YT +A NR G+ S  + L +   E
Sbjct: 243 PIRPDSAHKMLVRENGVHS----LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 298

Query: 732 -KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDT 786
             +PP  IE L++  V  G  V L  +V+G P P I W K N+ +      +    D   
Sbjct: 299 AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHG 358

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
           +   +++    +D G YT+ A+N  GI   +A + V
Sbjct: 359 YICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 394



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 86/333 (25%), Positives = 143/333 (42%), Gaps = 45/333 (13%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           G+ P F  K K   + EG  +   CR+   P+P I W   G++I P  +    I+ D+  
Sbjct: 67  GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDG 125

Query: 691 YCSVLKITNVKKFQEGTYT-----------------VVAVNREGEASL-----PIVLKIK 728
            CS L  T      +G YT                 V AVN+ G +       P V + +
Sbjct: 126 TCS-LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 184

Query: 729 T------GEKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
           +       E EP       P  ++    + V++G+   +  +V G P P ++W  + KP+
Sbjct: 185 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPI 244

Query: 776 KALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           +          +   HS+ I++P   +D G+YT  A N  G    S  + V    +E  +
Sbjct: 245 RPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA--AKEAHK 301

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIEL 890
           PP+FI + Q   V +   ++L  RV   P P I W + NE ++ S + ++ + D      
Sbjct: 302 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 361

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++    ++ D+G Y   A N AG  S  AR+ +
Sbjct: 362 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 394



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 68/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
           E    +E+   P F++        +G   + +C+V G P P ++W      I+P    +M
Sbjct: 193 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKM 252

Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618
              ++ V +L+I  V   DAG +TC+A N AG  S + EL V A    H           
Sbjct: 253 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK---------- 301

Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                         PP F +K +   V +G  + LECR++ +P P I W  + E +    
Sbjct: 302 --------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 347

Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
           +  V++  D H Y  +L I    K   G YTV A N  G  S    L + T   +  Q  
Sbjct: 348 D-RVSMHQDNHGYICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQST 405

Query: 739 EPLK 742
           +P K
Sbjct: 406 KPKK 409



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 6/153 (3%)

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
           EP +E    P F+    ++TV+E    ++  +V+  P P ++W  + + I P        
Sbjct: 195 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLV 254

Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939
               +  +I    +  D+G Y C+A+N AG++S    + +  ++      F++ LQ +  
Sbjct: 255 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-G 313

Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972
             +G  V LEC+       + +  KKE   + H
Sbjct: 314 VADGYPVRLECRVLGVPPPQIFW-KKENESLTH 345



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 16/187 (8%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544
            ++T +  +   + C   G+P P ++W  DGK ++   A      EN              
Sbjct: 212  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLIIEPVTSRD 271

Query: 1545 XXXYKCIAFNDHGEVETS--CVVGIQQ--KPVITISNEDIKQKHKVGDEWLV--TAVIEG 1598
               Y CIA N  G+   S   VV  ++  KP + I      Q   V D + V     + G
Sbjct: 272  AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLG 328

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSV 1656
            +PPP++ W K    L +  +     ++    I   I+   +  +  YT+ A N AG  S 
Sbjct: 329  VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 388

Query: 1657 EVTLKVY 1663
               L VY
Sbjct: 389  TARLDVY 395



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 16/191 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D  V+E  +  ++ +++   T D+ W+ DG+ I+P        +   +  L 
Sbjct: 204  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLI 263

Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y+CI  +     S + E+ V       PP  I +LQN  V  G     E
Sbjct: 264  IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 323

Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180
               L      + W K+   +  S + + +  D      L I     +DAG Y+     E 
Sbjct: 324  CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 383

Query: 1181 GNSKCTAILTV 1191
            G   CTA L V
Sbjct: 384  GIVSCTARLDV 394



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 7/115 (6%)

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           + E+   +   + + EN   P F  + +   + E   +    RV  NP P I W+++ + 
Sbjct: 50  VDESGDEVQYGDVSVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 109

Query: 873 ISPSE---TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ISP     TI ++ DG  ++    + +D   D G+Y  +A+N  G+ S   R+ +
Sbjct: 110 ISPKSDHYTIQRDLDGTCSLHTTASTLD---DDGNYTIMAANPQGRISCTGRLMV 161



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 1/76 (1%)

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            Y +    + ++ +  +Y  V  E  + +P  E  LK+        +  TC   G P+PK+
Sbjct: 43   YRLERSPVDESGDEVQYGDVSVENGM-APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKI 101

Query: 1514 TWYRDGKKLKTAKATY 1529
             W++DGK++      Y
Sbjct: 102  YWFKDGKQISPKSDHY 117


>UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep:
            Palladin - Homo sapiens (Human)
          Length = 1383

 Score =  127 bits (306), Expect = 4e-27
 Identities = 102/367 (27%), Positives = 162/367 (44%), Gaps = 23/367 (6%)

Query: 472  QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
            Q L+ E  Y +  +  ++E  D++   + P   E  MAP F  KL+     +G  V F C
Sbjct: 966  QRLISEIEY-RLERSPVDESGDEVQYGDVPV--ENGMAPFFEMKLKHYKIFEGMPVTFTC 1022

Query: 532  QVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            +V G P+P+I WF+    I P  D + +  D D   +L       +D G +T +A N  G
Sbjct: 1023 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 1082

Query: 591  FASSTTELIVEA-------PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK 641
              S T  L+V+A       P S  G                  + ++     P F + P 
Sbjct: 1083 RISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPG 1142

Query: 642  AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNV 700
               V EG    ++C++  +P PD++W   G+ + PD    + + E+ +H     L I  V
Sbjct: 1143 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS----LIIEPV 1198

Query: 701  KKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVV 759
                 G YT +A NR G+ S  + L +   E  +PP  IE L++  V  G  V L  +V+
Sbjct: 1199 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1258

Query: 760  GNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            G P P I W K N+ +      +    D   +   +++    +D G YT+ A+N  GI  
Sbjct: 1259 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1318

Query: 816  TSAVITV 822
             +A + V
Sbjct: 1319 CTARLDV 1325



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 87/333 (26%), Positives = 143/333 (42%), Gaps = 45/333 (13%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G+ P F  K K   + EG  +   CR+   P+P I W   G++I P  +    I+ D+  
Sbjct: 998  GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDG 1056

Query: 691  YCSVLKITNVKKFQEGTYT-----------------VVAVNREGEASL-----PIVLKIK 728
             CS L  T      +G YT                 V AVN+ G +       P V + +
Sbjct: 1057 TCS-LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 1115

Query: 729  T------GEKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
            +       E EP       P  ++    + V++G+   +  +V G P P ++W  + KPV
Sbjct: 1116 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 1175

Query: 776  KALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            +          +   HS+ I++P   +D G+YT  A N  G    S  + V    +E  +
Sbjct: 1176 RPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA--AKEAHK 1232

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIEL 890
            PP+FI + Q   V +   ++L  RV   P P I W + NE ++ S + ++ + D      
Sbjct: 1233 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1292

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ++    ++ D+G Y   A N AG  S  AR+ +
Sbjct: 1293 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1325



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%)

Query: 499  EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
            E    +E+   P F++        +G   + +C+V G P P ++W      ++P    +M
Sbjct: 1124 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 1183

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618
               ++ V +L+I  V   DAG +TC+A N AG  S + EL V A    H           
Sbjct: 1184 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK---------- 1232

Query: 619  XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                          PP F +K +   V +G  + LECR++ +P P I W  + E +    
Sbjct: 1233 --------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 1278

Query: 679  NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
            +  V++  D H Y  +L I    K   G YTV A N  G  S    L + T   +  Q  
Sbjct: 1279 D-RVSMHQDNHGYICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQST 1336

Query: 739  EPLK 742
            +P K
Sbjct: 1337 KPKK 1340



 Score = 83.0 bits (196), Expect = 8e-14
 Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 7/107 (6%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DD 562
           P+F ++L+     +G  V  EC+V G P  Q+ WFRQ + I+ S DF++         + 
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
           + + TLVI E FPEDAG FTC A+N  G A+ST +L+V +  +++ S
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 1/103 (0%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP F++KLR +   +GS V  EC+V G P P++ WF +   +  + D Q++ +  ++ TL
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610
           +I E F +D G +TC+A N +G  +++ E+ +E A  +D  SE
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 8/138 (5%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSIT 790
           P+ I+ L+S  V +G  V L  +V GNP P + W    K +   P        GD H++ 
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITVKEKG 848
           I +  +  D G YT  A N  G   TSA + +E    T+ ++E   F +R   +   +K 
Sbjct: 331 IAEAFE-DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389

Query: 849 TIKLVARV-TRNPVPSIT 865
           T  +   + + +P   +T
Sbjct: 390 TTSVSLTIGSSSPKTGVT 407



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 27/92 (29%), Positives = 46/92 (50%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
           P FI + +   V E   + L  RVT NP P + W+   + +  +  I  + +G ++  +I
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
                E D+G Y C+A+N +G  +  A V I+
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 35/153 (22%), Positives = 69/153 (45%), Gaps = 6/153 (3%)

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            EP +E    P F+    ++TV+E    ++  +V+  P P ++W  + + + P        
Sbjct: 1126 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLV 1185

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939
                +  +I    +  D+G Y C+A+N AG++S    + +  ++      F++ LQ +  
Sbjct: 1186 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-G 1244

Query: 940  TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972
              +G  V LEC+       + +  KKE   + H
Sbjct: 1245 VADGYPVRLECRVLGVPPPQIFW-KKENESLTH 1276



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692
           P F +K ++Q V EGS + LECR+   P P + W  +G+E+    +I +  E  D+H   
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH--- 327

Query: 693 SVLKITNVKKFQEGTYTVVAVNREG 717
             L I    +   G YT +A N  G
Sbjct: 328 -TLIIAEAFEDDTGRYTCLATNPSG 351



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 16/187 (8%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544
            ++T +  +   + C   G+P P ++W  DGK ++   A      EN              
Sbjct: 1143 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 1202

Query: 1545 XXXYKCIAFNDHGEVETS--CVVGIQQ--KPVITISNEDIKQKHKVGDEWLV--TAVIEG 1598
               Y CIA N  G+   S   VV  ++  KP + I      Q   V D + V     + G
Sbjct: 1203 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLG 1259

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSV 1656
            +PPP++ W K    L +  +     ++    I   I+   +  +  YT+ A N AG  S 
Sbjct: 1260 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 1319

Query: 1657 EVTLKVY 1663
               L VY
Sbjct: 1320 TARLDVY 1326



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 16/191 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D  V+E  +  ++ +++   T D+ W+ DG+ ++P        +   +  L 
Sbjct: 1135 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 1194

Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y+CI  +     S + E+ V       PP  I +LQN  V  G     E
Sbjct: 1195 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1254

Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180
               L      + W K+   +  S + + +  D      L I     +DAG Y+     E 
Sbjct: 1255 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1314

Query: 1181 GNSKCTAILTV 1191
            G   CTA L V
Sbjct: 1315 GIVSCTARLDV 1325



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---TITQNFD 884
            EN   P F  + +   + E   +    RV  NP P I W+++ + ISP     TI ++ D
Sbjct: 996  ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 1055

Query: 885  GE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            G  ++    + +D   D G+Y  +A+N  G+ S   R+ +
Sbjct: 1056 GTCSLHTTASTLD---DDGNYTIMAANPQGRISCTGRLMV 1092



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID-GKKQKLK 1164
            P  I +L++Q+V +G++   E  +T      VRWF +G E+  +  IQ+  + G    L 
Sbjct: 271  PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            I +   DD G Y+C   N
Sbjct: 331  IAEAFEDDTGRYTCLATN 348



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 1/76 (1%)

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            Y +    + ++ +  +Y  V  E  + +P  E  LK+        +  TC   G P+PK+
Sbjct: 974  YRLERSPVDESGDEVQYGDVPVENGM-APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKI 1032

Query: 1514 TWYRDGKKLKTAKATY 1529
             W++DGK++      Y
Sbjct: 1033 YWFKDGKQISPKSDHY 1048



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 62/278 (22%), Positives = 101/278 (36%), Gaps = 30/278 (10%)

Query: 930  FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
            F++ L +S E  EG  V LEC+ +   T   +W+   KE+      +I  EG        
Sbjct: 273  FIQKL-RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331

Query: 988  XXXXXD-VGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                 D  G   C+  +    +T++  V  E         +    K +  A+ + +  + 
Sbjct: 332  AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTT 391

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103
            +  +          PK           I+ L +    VH    Y C  R +      T  
Sbjct: 392  SVSLTIGSSS----PKTGV----TTAVIQPLSVPVQQVHSPTSYLC--RPDG----TTTA 437

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
              PP     LQN  V +G     E  +     L V+WF+ GSEIQ S   ++     +  
Sbjct: 438  YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497

Query: 1163 LKIYD-CDL-------DDAGEYSCEVGNSKCTAILTVE 1192
             +  + C L       +DAG ++C   N   +A  T +
Sbjct: 498  AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 10/106 (9%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--------TKSDGD 785
           PP   + L++  V +G+ V+L  +V G P   + W +    ++  P         +S  +
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 786 THSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
              I  L   +   +D G++T  A N  G A ++A + V     EN
Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 4/105 (3%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENISVAIESDMHM 690
           PP F+K+ +   V EG  ++LECR+   P   + W  +G EI   PD  I          
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 691 YCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKE 733
              +  +   + F E  G +T  A N  G A+    L + +   E
Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE 544



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 9/100 (9%)

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIE 889
           PP+F    Q   V E   + L  RV   P   + W+R    I  SP   I Q       E
Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499

Query: 890 ------LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
                 LVI     E D+G + C A N  G ++  A++ +
Sbjct: 500 PEEICTLVIAETFPE-DAGIFTCSARNDYGSATSTAQLVV 538


>UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion
            molecule-like protein 1 precursor (Down syndrome cell
            adhesion molecule 2).; n=1; Danio rerio|Rep: Down
            syndrome cell adhesion molecule-like protein 1 precursor
            (Down syndrome cell adhesion molecule 2). - Danio rerio
          Length = 1862

 Score =  126 bits (303), Expect = 9e-27
 Identities = 280/1349 (20%), Positives = 487/1349 (36%), Gaps = 128/1349 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V  G  I L C     P P I WL  G  +  D   +  +          L I++++   
Sbjct: 70   VQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG--------LTISDLRLED 121

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
             G Y     N  G   +   L +     EP +V    K++      +VILS  V G+P  
Sbjct: 122  SGNYICEVTNSFGSKEVTGHLNVI----EPLRVTLSPKNLKTGISSTVILSCAVQGSPHF 177

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            T++W +N +P+      S    H+ T+ +   + +  G Y   A      A+  ++I +E
Sbjct: 178  TVSWFRNTEPIVPDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLE 237

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN- 882
            + T      P  ++ F E  V       L+      P P+ITW  ++E ++       + 
Sbjct: 238  DGT------PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQ 291

Query: 883  ---FDGENIELV-ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                DG  +  V +TN     D G Y+C A NSAG + + AR  I+V     ++ + ++ 
Sbjct: 292  YTLSDGSTVSHVNVTNPQIR-DGGVYRCAARNSAGSAEYQAR--INVRGPPSIRAM-RNI 347

Query: 939  ETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
                G+   + C+       S KWY +   +   +HR+++ E              D G 
Sbjct: 348  TAVAGRNTFINCRVIGYPYYSIKWYKDGMLLPD-NHRQVVYE-NGTLKLSDVQKGMDEGA 405

Query: 997  IKCIVKDQ---ETSTMLVVKETIPEFIRKLQDF---EVKEKDVAILEVEINSETADVVWE 1050
              C V  Q     S  + V   +P  I+   DF    + +       V        + W 
Sbjct: 406  YLCSVLIQPQLSISQTVYVTVKVPPLIQPF-DFPPTSIGKLMYIACVVSSGDMPIRITWR 464

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPP 1107
            +DG+ I         E +  +  L I   S+   G Y+CI  +++ T       +V +PP
Sbjct: 465  KDGQEIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPP 524

Query: 1108 EIITRLQNQK--VNKGNKATFEIELTKGDALVRWFKDG-------SEIQFSNHIQLTIDG 1158
                +  NQ     K       +E      +V     G         +  +  IQ+  +G
Sbjct: 525  RFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNG 584

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTD 1213
                L I     +D G Y C+  N        + +LTV+ P++  +       +   N +
Sbjct: 585  ---SLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSHPNTTMAIKGQNKE 641

Query: 1214 AYLTVEIPDETLDVTWYKKKSVIED--TEKFTLI------SDVKKRTLIIRKCTEDDQCE 1265
               T    +  + + W +  +VI+     ++++       SD    TL ++     D   
Sbjct: 642  LNCTAR-GEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERGDSVF 700

Query: 1266 YTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDV--TLLVDYQAFPQPNDEWI 1322
            ++C  +++    +  +++ V+ PP   + E      R  ++  T   D  +     D   
Sbjct: 701  FSCHAINSYGEGRGLIQLTVQEPPDPPELEVREVKDRSMNLRWTQRFDGNSIITSYDIEY 760

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDK 1380
             N     + KH    I   +    I  VE   A +Y +R+   N  G +     +TI  +
Sbjct: 761  KNKSDPWELKHATRKISPTNNQANI--VELHPASVYSIRMYSYNKIGRSQASKELTISTE 818

Query: 1381 PSPPGKPN---ILE-IDSSSINICWDEP-ENTGNSTIIYYVVEYQE--IDTTEWISVKNI 1433
             +PP  P    IL+ + S SI + W  P +   N  I  Y + Y+E    +    S+  +
Sbjct: 819  EAPPDGPPMEVILQPMTSQSIRVTWKAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEM 878

Query: 1434 TKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASE-----TTEYYKVIKETKIQSPTV 1484
              T  S    + NLK  + Y     A N      +S      T E         +++ TV
Sbjct: 879  KATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPQNVRAITV 938

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544
                  IT      + L  +  G      + Y DG+  +    T   R            
Sbjct: 939  TSDEAVITWSEPPRMTLNGVLKGYRVVFWSLYPDGEWGEMQNIT-TTREQVELKGLEKFT 997

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK----QKHKVGDEWLVTAVIEGIP 1600
                + +A+   G+   S V+ IQ +         IK        V   WL      GI 
Sbjct: 998  NYSVQVLAYTQAGDGVRSNVLYIQTREDHPGPPAGIKAVPSSASSVVVSWLPPVKPNGII 1057

Query: 1601 PPEVIWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
                I+  + G+      EY      +  + RI  L R         A  TAG  ++   
Sbjct: 1058 RKYTIYCSSPGSGQPAPSEYE--ANPELLIYRITHLTRGQQYLIWAAAVTTAGRGNISEK 1115

Query: 1660 LKVYDKPSKPEGPVIMREIS-RESVTIEW----KPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            + V     +P G    + +S   +VT  W    + P    G E T       + ++    
Sbjct: 1116 VTV-----EPAGKAPAKILSFGGTVTTPWMKEVRLPCSSVG-EPTPTIKWTKDSEDTAIP 1169

Query: 1715 KVADVDRDV---ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
               D  R++    T  ++ +       +   A N +GF      + I++   + VP    
Sbjct: 1170 VTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGF------DTIIVNLLVQVPPDQP 1223

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXA-RIQKL 1829
                       S+ + W P + NGGS I  + ++   +  ++WK         + ++  L
Sbjct: 1224 RLTVSTT-STSSITLAWIPGD-NGGSSIRGFVLQYSVDNTEEWKDVFISSSERSFKLDNL 1281

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK-WTE 1888
               T Y+ ++ A+N +G        +  T G+          F    ST   + L+ WT 
Sbjct: 1282 RCGTWYKVKLAAKNSVGAGRISEIIEAKTHGREPQFNKDQPLFTHINSTHARMNLQGWT- 1340

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
               +GG PIT  ++EF+     +W  + T
Sbjct: 1341 ---SGGCPITAVLLEFRPKGTWAWQSVRT 1366



 Score =  120 bits (289), Expect = 4e-25
 Identities = 199/995 (20%), Positives = 370/995 (37%), Gaps = 90/995 (9%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            E  P ++   Q+ +V  G       I     +  +RW KDG  +   +     + G    
Sbjct: 56   ESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG---- 111

Query: 1163 LKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
            L I D  L+D+G Y CEV NS    + T  L V EP +  TL  P+ +    ++   L+ 
Sbjct: 112  LTISDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEP-LRVTLS-PKNLKTGISSTVILSC 169

Query: 1219 EIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277
             +       V+W++    I   + F+ I      TL I    +     Y C     K  T
Sbjct: 170  AVQGSPHFTVSWFRNTEPIVPDQHFS-IQGAHNETLFITAAQKRHSGAYQC-FATRKGQT 227

Query: 1278 KLKVEVV---EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
                 ++   +  P+IV    E  +  G   +L+   +  P P   W ++ + + +    
Sbjct: 228  AQDFSIILLEDGTPRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAH 287

Query: 1335 KPSIDSKSASLTIKKVENT-----DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
            + S  + S   T+  V  T     D G+Y+    N+ G A+ +  + +   PS     NI
Sbjct: 288  RASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRNI 347

Query: 1390 LEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
              +   +  I C          +I +Y       D    +  +N T   + +Q      +
Sbjct: 348  TAVAGRNTFINC--RVIGYPYYSIKWYKDGMLLPDNHRQVVYENGTLKLSDVQKGMDEGA 405

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508
            Y        ++ IS     T          ++ P + +P     T   + + + C+    
Sbjct: 406  YLCSVLIQPQLSISQTVYVT----------VKVPPLIQPFDFPPTSIGKLMYIACVVSSG 455

Query: 1509 PQP-KVTWYRDGKKL--KTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
              P ++TW +DG+++   TA  T E +                  Y CIA ND   V + 
Sbjct: 456  DMPIRITWRKDGQEIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSE 515

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-- 1620
              + +   P   +   +  Q    G   ++   +EG PPP+V+W K+   + N ++Y+  
Sbjct: 516  RQLIVTVPPRFRVQPNN--QDGIYGKSEVLNCSVEGYPPPKVVW-KHAKGIGNPQQYHPV 572

Query: 1621 -ITTKEK---TSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDK-PSKPEGP 1672
             +T + +      + I+ +       Y  +ASN  G   + S+ +T+K+     S P   
Sbjct: 573  PLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSHPNTT 632

Query: 1673 VIMREISRE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-----DVDRDVETY 1726
            + ++  ++E + T   + P+    +   +      +PD N    +        D  + T 
Sbjct: 633  MAIKGQNKELNCTARGEYPI----IIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTL 688

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             ++         F   A N  G    L    + ++   D P           + + S+ +
Sbjct: 689  KLKPAERGDSVFFSCHAINSYGEGRGLIQ--LTVQEPPDPPE-----LEVREVKDRSMNL 741

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX-----XXXXARIQKLSINTTYQFRIYA 1841
             W     +G S I  Y +E K +   W+              A I +L   + Y  R+Y+
Sbjct: 742  RW-TQRFDGNSIITSYDIEYKNKSDPWELKHATRKISPTNNQANIVELHPASVYSIRMYS 800

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GGSPITN 1899
             N+IG S    +  ++TI     PP   P   ++   TS+S+ + W  P+       I  
Sbjct: 801  YNKIGRS---QASKELTISTEEAPPDGPPMEVILQPMTSQSIRVTWKAPKKELQNGVIRG 857

Query: 1900 YIIEFKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            Y I ++       G+     +   G    + ++N+K+  +    + A N  G   P+ S+
Sbjct: 858  YQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSE 916

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLLGYNIAIRDV-TKTMW 2013
             +       VPS P   +    V S+  + +W   P       L GY +    +     W
Sbjct: 917  -INATTLEDVPSQPPQNVRAITVTSDEAVITWSEPPRMTLNGVLKGYRVVFWSLYPDGEW 975

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             E+  +     +  ++ L +   Y +++ A  + G
Sbjct: 976  GEMQNITTTREQVELKGLEKFTNYSVQVLAYTQAG 1010



 Score =  117 bits (282), Expect = 3e-24
 Identities = 175/814 (21%), Positives = 323/814 (39%), Gaps = 69/814 (8%)

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784
            L +    +  P V++  +S  V+ G S+ L     G P PTI W K+ +P+ A  ++   
Sbjct: 49   LSVLDPTESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPA-DSRWTR 107

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
                +TI    +++D G Y  +  NS G  E +  + V EP      P       + +  
Sbjct: 108  RLTGLTI-SDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEPLRVTLSP-------KNLKT 159

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
                T+ L   V  +P  +++W+RN E I P +    +  G + E +      +  SG Y
Sbjct: 160  GISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHF--SIQGAHNETLFITAAQKRHSGAY 217

Query: 905  KCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHN 963
            +C A+     +   + + ++      V    ++     E  +++   + +   +  W  +
Sbjct: 218  QCFATRKGQTAQDFSIILLEDGTPRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLD 277

Query: 964  KKEIS-GMDHRE---IIQEGRXXXXXXXXX-XXXDVGVIKCIVKDQETSTMLVVKETI-- 1016
             + ++    HR     + +G              D GV +C  ++   S     +  +  
Sbjct: 278  DEPVARDSAHRASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRG 337

Query: 1017 PEFIRKLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P  IR +++   V  ++  I    I      + W +DG ++ P  ++    + G ++   
Sbjct: 338  PPSIRAMRNITAVAGRNTFINCRVIGYPYYSIKWYKDGMLL-PDNHRQVVYENGTLKLSD 396

Query: 1076 IRNTSVHDEGEYSC-ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT 1131
            ++     DEG Y C +L     +   TV   V++PP +I        + G        ++
Sbjct: 397  VQKGM--DEGAYLCSVLIQPQLSISQTVYVTVKVPP-LIQPFDFPPTSIGKLMYIACVVS 453

Query: 1132 KGDALVR--WFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGNSKCTA 1187
             GD  +R  W KDG EI  S    +TI+ K+    L+I    L   G Y+C   N   T 
Sbjct: 454  SGDMPIRITWRKDGQEI-VSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAAT- 511

Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLD------VTWYKKKSVIEDTE 1240
                 E  +  T+  P F + P N D  Y   E+ + +++      V W   K +    +
Sbjct: 512  --VSSERQLIVTVP-PRFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQ 568

Query: 1241 KFTL-----ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDY 1293
               +     I  +   +L+IR   E+D+  Y C   +      +K  +  V+ P  I  +
Sbjct: 569  YHPVPLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSH 628

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--------DSKSASL 1345
                   +G +  L    +        W     +I   ++ + SI        D   ++L
Sbjct: 629  PNTTMAIKGQNKELNCTARGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTL 688

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
             +K  E  D+  +     N+ G     + +T+ + P PP +  + E+   S+N+ W +  
Sbjct: 689  KLKPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPP-ELEVREVKDRSMNLRWTQ-R 746

Query: 1406 NTGNSTIIYYVVEYQEIDTTEW---ISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
              GNS I  Y +EY+   +  W    + + I  T  Q +I  L   S Y  R Y+ N++ 
Sbjct: 747  FDGNSIITSYDIEYKN-KSDPWELKHATRKISPTNNQANIVELHPASVYSIRMYSYNKIG 805

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
             S AS+  E     +E     P +E  L+ +T++
Sbjct: 806  RSQASK--ELTISTEEAPPDGPPMEVILQPMTSQ 837



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 77/287 (26%), Positives = 120/287 (41%), Gaps = 28/287 (9%)

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
           +++E +  T S  PK       S ++L C +   P   ++W    E IVPD++ S+    
Sbjct: 143 NVIEPLRVTLS--PKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHFSI---- 196

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
               +   L IT  +K   G Y   A  +   A    ++ ++ G    P+++      +V
Sbjct: 197 -QGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLEDGT---PRIVSSFSERVV 252

Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVK-------ALPTKSDGDTHSITILKPKKVKD 799
             GE   L     G P PTITW  +++PV        +  T SDG T S   +   +++D
Sbjct: 253 APGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSHVNVTNPQIRD 312

Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            GVY   A NS G AE  A I V  P          I   + IT        +  RV   
Sbjct: 313 GGVYRCAARNSAGSAEYQARINVRGPPS--------IRAMRNITAVAGRNTFINCRVIGY 364

Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
           P  SI WY++  ++  +    +    EN  L +++V   +D G Y C
Sbjct: 365 PYYSIKWYKDGMLLPDNH---RQVVYENGTLKLSDVQKGMDEGAYLC 408



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 97/439 (22%), Positives = 168/439 (38%), Gaps = 34/439 (7%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678
            NITT  +   + +K L++  +    + A   AG       L +  +   P  P  ++ + 
Sbjct: 980  NITTTREQ--VELKGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDHPGPPAGIKAVP 1037

Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736
             S  SV + W PP+   G+ + KY I    P + +      + + ++  Y I  L    +
Sbjct: 1038 SSASSVVVSWLPPVKPNGI-IRKYTIYCSSPGSGQPAPSEYEANPELLIYRITHLTRGQQ 1096

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y+    A    G      SE + ++ A   P+              +V   W    +   
Sbjct: 1097 YLIWAAAVTTAGRGNI--SEKVTVEPAGKAPAKILSFGG-------TVTTPWMKEVRLPC 1147

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
            S + +    IK   K  +              LS N T   R     + G    T+    
Sbjct: 1148 SSVGEPTPTIKWT-KDSEDTAIPVTQDGHRNILS-NGTLVLRSVKAEDSGYYTCTATNTL 1205

Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
              D I +   +  PP QPR  V + STS S+TL W  P  NGGS I  +++++     + 
Sbjct: 1206 GFDTIIVNLLVQVPPDQPRLTVSTTSTS-SITLAWI-PGDNGGSSIRGFVLQYSVDNTEE 1263

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS-PPT 1970
            W K V +  S     ++N++       +++A+N+VG      S+ +  + H   P     
Sbjct: 1264 W-KDVFISSSERSFKLDNLRCGTWYKVKLAAKNSVGAG--RISEIIEAKTHGREPQFNKD 1320

Query: 1971 APLEIRMVGSNIVMTSWGTPEW-DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029
             PL   +  ++  M   G   W  GG P+    +  R      W  V + + +   F + 
Sbjct: 1321 QPLFTHINSTHARMNLQG---WTSGGCPITAVLLEFRPKGTWAWQSV-RTNASADIF-LA 1375

Query: 2030 DLSENHTYMIRIYARNEIG 2048
            +L E   Y +++ A N  G
Sbjct: 1376 ELREATWYELKMKACNSAG 1394



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 61/254 (24%), Positives = 101/254 (39%), Gaps = 15/254 (5%)

Query: 1598 GIPPPEVIWYKNGNK----LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            G P P + W K+       +  D   NI +   T V+R   +K   S  YT  A+NT G 
Sbjct: 1151 GEPTPTIKWTKDSEDTAIPVTQDGHRNILSNG-TLVLR--SVKAEDSGYYTCTATNTLGF 1207

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
             ++ V L V   P +P   + +   S  S+T+ W P  D+GG  +  + ++ +  DN   
Sbjct: 1208 DTIIVNLLVQVPPDQPR--LTVSTTSTSSITLAWIPG-DNGGSSIRGFVLQ-YSVDNTEE 1263

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
             K   +     ++ +  L     Y  ++ A+N VG      SE I  KT    P      
Sbjct: 1264 WKDVFISSSERSFKLDNLRCGTWYKVKLAAKNSVGAGRI--SEIIEAKTHGREPQFNKDQ 1321

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSIN 1832
                 I++    +       +GG PI    +E + +G   W+           + +L   
Sbjct: 1322 PLFTHINSTHARMN-LQGWTSGGCPITAVLLEFRPKGTWAWQSVRTNASADIFLAELREA 1380

Query: 1833 TTYQFRIYARNEIG 1846
            T Y+ ++ A N  G
Sbjct: 1381 TWYELKMKACNSAG 1394



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 5/110 (4%)

Query: 497  VFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPS 553
            + EK T E    AP  +        TP    V+  C   G P P I W + +    I  +
Sbjct: 1112 ISEKVTVEPAGKAPAKILSFGGTVTTPWMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVT 1171

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            QD       +   TLV+R V  ED+G +TC A N  GF +    L+V+ P
Sbjct: 1172 QDGHRNILSNG--TLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQVP 1219



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 66/382 (17%), Positives = 133/382 (34%), Gaps = 27/382 (7%)

Query: 1245 ISDVKKR-TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
            ISDV+K   L   +C    +  Y+     +       ++  E  P ++D  +   ++ G 
Sbjct: 17   ISDVQKEDALSTYRCITKHK--YSGETRQSNGARLSVLDPTESTPSVMDSFQSGEVQVGR 74

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
             + L      +P P   W+ + + +         +      LTI  +   D+G Y   + 
Sbjct: 75   SIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRL----TGLTISDLRLEDSGNYICEVT 130

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
            N+ G  +V  ++ +++       P  L+   SS  I     + + + T+ ++    + I 
Sbjct: 131  NSFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWFR-NTEPIV 189

Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
              +  S++        I   +   S  ++ +A  +       +T + + +I   +  +P 
Sbjct: 190  PDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRK------GQTAQDFSIIL-LEDGTPR 242

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
            +          P E   L C   G P P +TW  D + +    A   ++           
Sbjct: 243  IVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSH 302

Query: 1544 XXXX---------YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y+C A N  G  E    + ++  P I             G    +  
Sbjct: 303  VNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRNITA---VAGRNTFINC 359

Query: 1595 VIEGIPPPEVIWYKNGNKLEND 1616
             + G P   + WYK+G  L ++
Sbjct: 360  RVIGYPYYSIKWYKDGMLLPDN 381



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD----NVATLVIREVFPEDAG 579
           G +    C VEGYP P++ W     I  P Q   +         +  +L+IR V  ED G
Sbjct: 538 GKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNGSLLIRHVLEEDRG 597

Query: 580 TFTCVAKNAAGF-ASSTTELIVEAP 603
            + C A N  G   S +  L V+ P
Sbjct: 598 YYLCQASNGVGSDISKSMMLTVKIP 622



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)

Query: 516 LRPKHTPDG--STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
           L PK+   G  STV   C V+G P   ++WFR T  I P Q F +     +  TL I   
Sbjct: 152 LSPKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHFSI--QGAHNETLFITAA 209

Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601
               +G + C A      A   + +++E
Sbjct: 210 QKRHSGAYQCFATRKGQTAQDFSIILLE 237



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)

Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME--VGKVD 2020
            TV  PP  P LE+R V    +   W T  +DG + +  Y+I  ++ +    ++    K+ 
Sbjct: 719  TVQEPPDPPELEVREVKDRSMNLRW-TQRFDGNSIITSYDIEYKNKSDPWELKHATRKIS 777

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
                + NI +L     Y IR+Y+ N+IG S+
Sbjct: 778  PTNNQANIVELHPASVYSIRMYSYNKIGRSQ 808



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 51/260 (19%), Positives = 90/260 (34%), Gaps = 20/260 (7%)

Query: 584 VAKNAAGFASSTTELIVEAPLSD----HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
           +    AG    T E +    +S     H    T               ++  +PP F  +
Sbjct: 470 IVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPPRFRVQ 529

Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKIT 698
           P  Q    G   +L C +   P P + W        P +   V +   + +  +  L I 
Sbjct: 530 PNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNGSLLIR 589

Query: 699 NVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
           +V +   G Y   A N  G + S  ++L +K     P  +     + +  +G++  L+  
Sbjct: 590 HVLEEDRGYYLCQASNGVGSDISKSMMLTVKI----PAMITSHPNTTMAIKGQNKELNCT 645

Query: 758 VVGNPRPTITWCKNNK----------PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
             G     I W + +            +   P +   +  S   LKP +  D   ++  A
Sbjct: 646 ARGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERGDSVFFSCHA 705

Query: 808 ENSEGIAETSAVITVEEPTE 827
            NS G       +TV+EP +
Sbjct: 706 INSYGEGRGLIQLTVQEPPD 725



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 22/95 (23%), Positives = 37/95 (38%), Gaps = 5/95 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P  ++  +      G +++  C   GYP P I W +    +     +        +  L 
Sbjct: 59  PSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTR-----RLTGLT 113

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
           I ++  ED+G + C   N+ G    T  L V  PL
Sbjct: 114 ISDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEPL 148



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 4/100 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY---DDDNV 565
           P  V     +    G      C  +G P P ITW      + + S      Y   D   V
Sbjct: 241 PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTV 300

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
           + + +      D G + C A+N+AG A     + V  P S
Sbjct: 301 SHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPS 340


>UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 553

 Score =  126 bits (303), Expect = 9e-27
 Identities = 92/352 (26%), Positives = 151/352 (42%), Gaps = 23/352 (6%)

Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
           V + EP + W     EIVPD       + + +     L + ++K    G Y  +A N  G
Sbjct: 207 VQVEEPSVTWYRNKNEIVPDGRSRTTFDGETYK----LILQDIKIKDAGQYECIASNPIG 262

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
           +A     + +   ++E P  +  L+ + V +G++V    +V G PRPT+ W ++N+P++A
Sbjct: 263 KAFCTAEMTVN--KREAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRA 320

Query: 778 -LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
               K D D    ++ L     KD+GVY     NS G A +SA + V    ++ A  P  
Sbjct: 321 DTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQV----DKKANKPKV 376

Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
           I +  ++   E    +   R +  P P +TWYRN+  +        + DG+   L IT+ 
Sbjct: 377 IEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDT 436

Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955
              +D+G YKCVA+N  GK +  +R  +DV +  F        E +E   V      +  
Sbjct: 437 -KLVDTGTYKCVATNEGGKIT--SRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFK 493

Query: 956 VSTK--------WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
           V  +        WY + + +  +   EI   G             D G   C
Sbjct: 494 VRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTC 545



 Score =  122 bits (294), Expect = 1e-25
 Identities = 128/573 (22%), Positives = 231/573 (40%), Gaps = 62/573 (10%)

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
            ++  + P F+++ + I + E    +L   VT  P P + W+R+  +I PS     ++DG 
Sbjct: 10   QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 69

Query: 887  NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
               L +   + + D G YKCV +N+ G  S  A VT+  + +   +     +E E+    
Sbjct: 70   VSALTVKEAELD-DDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFE-EKQFLE 127

Query: 947  ILECQTSHTV------------STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994
             LE Q    V            +  W+ N KE+    H EI   G             D 
Sbjct: 128  PLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDA 187

Query: 995  GVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD-G 1053
            G  KC+ ++                     D    E+   + EV++  E   V W R+  
Sbjct: 188  GSYKCLARN---------------------DVGSAER---LFEVQV--EEPSVTWYRNKN 221

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVEL-PPE 1108
            EI+   +++  F+  G   KL +++  + D G+Y CI    +    CTAE+TV +   P 
Sbjct: 222  EIVPDGRSRTTFD--GETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPV 279

Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
             +++L+   V +G+  ++  ++       V W++D   ++     ++  DG+   L + +
Sbjct: 280  FVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSE 339

Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVE---EPSINFTLRLPEF--ILVPANTDAYLTVEIPD 1222
             D  D G Y+C + NS  +A  + E   +   N    + +   +     T+A   V    
Sbjct: 340  ADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSG 399

Query: 1223 -ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK- 1278
                +VTWY+    + +  +F L  D  + +L I      D   Y CV  +   K T++ 
Sbjct: 400  LPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRG 459

Query: 1279 -LKVEVVEFPPKIV--DYEREYRIKRGSD-VTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
             L V   +F P+    D  +E  + + SD +   V  +  P P   W  + ++++  +  
Sbjct: 460  DLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRF 519

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            +        +         DAG Y     N  G
Sbjct: 520  EIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552



 Score =  121 bits (291), Expect = 3e-25
 Identities = 89/343 (25%), Positives = 154/343 (44%), Gaps = 26/343 (7%)

Query: 764  PTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
            P++TW +N     P     T  DG+T+ + IL+  K+KD G Y   A N  G A  +A +
Sbjct: 212  PSVTWYRNKNEIVPDGRSRTTFDGETYKL-ILQDIKIKDAGQYECIASNPIGKAFCTAEM 270

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            TV +      E P+F+++ + + V E   +  + +V   P P++ WYR+N+ +       
Sbjct: 271  TVNK-----REAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWK 325

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK--SY 938
             +FDG    L ++  D + D G Y CV +NSAG +   A + +D +K    K ++K    
Sbjct: 326  MDFDGRVCSLFLSEADCK-DKGVYNCVITNSAGSAFSSAELQVD-KKANKPKVIEKMNDV 383

Query: 939  ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
            +T EG     + + S        WY N  ++       + ++G             D G 
Sbjct: 384  QTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGT 443

Query: 997  IKCIVKDQ----ETSTMLVVKET--IPEFI---RKLQDFEVKEKDVAILEVEINSE-TAD 1046
             KC+  ++     +   L V+E    PEF       +   V+E D    +V +  +    
Sbjct: 444  YKCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPT 503

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            +VW +DGE+++  + +++   RG I      + S  D G Y+C
Sbjct: 504  IVWYKDGEMVRDVR-RFEIRSRGDIYTFATYSASAEDAGTYTC 545



 Score =  116 bits (278), Expect = 9e-24
 Identities = 101/390 (25%), Positives = 161/390 (41%), Gaps = 45/390 (11%)

Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
           FE QVE    P +TW+R    I P    +  +D +    L+++++  +DAG + C+A N 
Sbjct: 205 FEVQVE---EPSVTWYRNKNEIVPDGRSRTTFDGETYK-LILQDIKIKDAGQYECIASNP 260

Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648
            G A  T             +EMTV                    P F  K +  +V EG
Sbjct: 261 IGKAFCT-------------AEMTVNKREA---------------PVFVSKLRPLFVTEG 292

Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708
            ++   C++  +P P + W    + +  D    +  +  +   CS L ++      +G Y
Sbjct: 293 DNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRV---CS-LFLSEADCKDKGVY 348

Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
             V  N  G A     L++   +   P+VIE +  +   +G       +  G PRP +TW
Sbjct: 349 NCVITNSAGSAFSSAELQVDK-KANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTW 407

Query: 769 CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            +N+  V+         DGD +S+TI   K V D G Y   A N  G   +   + V E 
Sbjct: 408 YRNSIKVRNESRFHLSEDGDRYSLTITDTKLV-DTGTYKCVATNEGGKITSRGDLDVRE- 465

Query: 826 TEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
             + A      +  +E + V+E   I    RV   PVP+I WY++ E++           
Sbjct: 466 -RQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSR 524

Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGK 914
           G+       +  +E D+G Y C ASN  GK
Sbjct: 525 GDIYTFATYSASAE-DAGTYTCEASNKLGK 553



 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 120/563 (21%), Positives = 222/563 (39%), Gaps = 58/563 (10%)

Query: 733  EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSI 789
            + P  +  L+ + + +G+   LS  V G P+P + W ++    KP +      DG+  ++
Sbjct: 14   DTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 73

Query: 790  TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKG 848
            T+ + +   D     +   N   ++  + V  +++    E    P+F         +EK 
Sbjct: 74   TVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIF---------EEKQ 124

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
             ++ +    R PV  ++++       P  T+T   +G+ +              D K V 
Sbjct: 125  FLEPLEIQVRQPV-EVSYHVRGR---PKPTVTWWKNGKELR-------------DGKHVE 167

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968
              S G       +  + E     K L ++      +  + E Q     S  WY NK EI 
Sbjct: 168  IRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAER--LFEVQVEEP-SVTWYRNKNEIV 224

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-----TSTMLVVKETIPEFIRKL 1023
                     +G             D G  +CI  +       T+ M V K   P F+ KL
Sbjct: 225  PDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKL 284

Query: 1024 QDFEVKEKD-VAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSV 1081
            +   V E D V+ +          V W RD + ++     K DF+  G +  L++     
Sbjct: 285  RPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFD--GRVCSLFLSEADC 342

Query: 1082 HDEGEYSCILRDES----CTAEVTVVELP--PEIITRLQNQKVNKGNKATFEIELTK-GD 1134
             D+G Y+C++ + +     +AE+ V +    P++I ++ + +  +G +A F++  +    
Sbjct: 343  KDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPR 402

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAI--LT 1190
              V W+++  +++  +   L+ DG +  L I D  L D G Y C   N   K T+   L 
Sbjct: 403  PEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLD 462

Query: 1191 VEE----PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI 1245
            V E    P       L E ++V  +      V +  + +  + WYK   ++ D  +F + 
Sbjct: 463  VRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIR 522

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTC 1268
            S     T      + +D   YTC
Sbjct: 523  SRGDIYTFATYSASAEDAGTYTC 545



 Score = 93.1 bits (221), Expect = 8e-17
 Identities = 109/485 (22%), Positives = 195/485 (40%), Gaps = 60/485 (12%)

Query: 929  TFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXX 986
            TF+  L+   E  EG    L C  +       +W+ ++  I      +   +G       
Sbjct: 17   TFMSKLEP-IEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTV 75

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETI-PEFIRKLQDFE--VKEKD-VAILEVEINS 1042
                  D GV KC+V +   S       T+  + +R  +D+    +EK  +  LE+++  
Sbjct: 76   KEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQ 135

Query: 1043 ETA-----------DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
                           V W ++G+ ++  K+  +    G    LYI  +   D G Y C+ 
Sbjct: 136  PVEVSYHVRGRPKPTVTWWKNGKELRDGKH-VEIRSGGTYHTLYILRSEEEDAGSYKCLA 194

Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151
            R++  +AE            RL            FE+++ +    V W+++ +EI     
Sbjct: 195  RNDVGSAE------------RL------------FEVQVEEPS--VTWYRNKNEIVPDGR 228

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV---EEPSINFTLRLPE 1204
             + T DG+  KL + D  + DAG+Y C     +G + CTA +TV   E P     LR P 
Sbjct: 229  SRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKLR-PL 287

Query: 1205 FILVPANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
            F+    N      V  +P  T++  WY+    +    ++ +  D +  +L + +    D+
Sbjct: 288  FVTEGDNVSWMCKVAGMPRPTVE--WYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDK 345

Query: 1264 CEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319
              Y CV+ +    A S+ +L+V+     PK+++   + +   G++    V +   P+P  
Sbjct: 346  GVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEV 405

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             W  NS  ++       S D    SLTI   +  D G YK    N  G      ++ + +
Sbjct: 406  TWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLDVRE 465

Query: 1380 KPSPP 1384
            +   P
Sbjct: 466  RQFAP 470



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 58/208 (27%), Positives = 101/208 (48%), Gaps = 17/208 (8%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDM 688
           +G  PTF  K +   + EG D  L C +   P+P++ W F+ E ++ P      + + ++
Sbjct: 12  KGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQW-FRDEVLIKPSRRFKASYDGNV 70

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGEKEPPQVIEP---L 741
               S L +   +   +G Y  V  N  G    +A + ++ K    E++   + E    L
Sbjct: 71  ----SALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFL 126

Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798
           + + ++  + V +S  V G P+PT+TW KN K +   K +  +S G  H++ IL+ ++ +
Sbjct: 127 EPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEE-E 185

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPT 826
           D G Y   A N  G AE    + VEEP+
Sbjct: 186 DAGSYKCLARNDVGSAERLFEVQVEEPS 213



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 95/405 (23%), Positives = 171/405 (42%), Gaps = 64/405 (15%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHI 1071
            K   P F+ KL+  E+ E D   L   +      +V W RD  +IKP + ++     G++
Sbjct: 12   KGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSR-RFKASYDGNV 70

Query: 1072 RKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE--LPPE-----IITRLQ-----N 1115
              L ++   + D+G Y C++ +     S  A+VTV++  L PE     I    Q      
Sbjct: 71   SALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLE 130

Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
             +V +  + ++ +   +    V W+K+G E++   H+++   G    L I   + +DAG 
Sbjct: 131  IQVRQPVEVSYHVR-GRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGS 189

Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            Y C    +VG+++    + VEEPS+ +     E               +PD     T+  
Sbjct: 190  YKCLARNDVGSAERLFEVQVEEPSVTWYRNKNEI--------------VPDGRSRTTF-- 233

Query: 1232 KKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEF 1286
                  D E + LI  D+K +          D  +Y C+  +    A  T ++ V   E 
Sbjct: 234  ------DGETYKLILQDIKIK----------DAGQYECIASNPIGKAFCTAEMTVNKRE- 276

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             P  V   R   +  G +V+ +      P+P  EW  +++ ++     K   D +  SL 
Sbjct: 277  APVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLF 336

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
            + + +  D G+Y   + N+ G A     + + DK +   KP ++E
Sbjct: 337  LSEADCKDKGVYNCVITNSAGSAFSSAELQV-DKKA--NKPKVIE 378



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           +++   P F+ KL P    +G   Q  C V G P+P++ WFR   +IKPS+ F+  Y D 
Sbjct: 10  QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASY-DG 68

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           NV+ L ++E   +D G + CV  N  G  SS  ++ V
Sbjct: 69  NVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 105



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 35/93 (37%), Positives = 53/93 (56%), Gaps = 1/93 (1%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP+FV KLRP    +G  V + C+V G PRP + W+R    ++    ++M + D  V +L
Sbjct: 277 APVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDF-DGRVCSL 335

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            + E   +D G + CV  N+AG A S+ EL V+
Sbjct: 336 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVD 368



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 66/348 (18%), Positives = 131/348 (37%), Gaps = 17/348 (4%)

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEM 1373
            +P+  W  N   I     ++ + D ++  L ++ ++  DAG Y+    N  G A    EM
Sbjct: 211  EPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEM 270

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
             V   + P    K   L +     N+ W  +       T+ +Y         T W    +
Sbjct: 271  TVNKREAPVFVSKLRPLFVTEGD-NVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFD 329

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
                   +          +     N    + +S   +  K     K   P V + + ++ 
Sbjct: 330  GRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDK-----KANKPKVIEKMNDVQ 384

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXY 1548
            T    +      F G+P+P+VTWYR+  K++     +     +R               Y
Sbjct: 385  TVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTY 444

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVT--AVIEGIPPPEV 1604
            KC+A N+ G++ +   + ++++        ++++K+   V +   +     + G P P +
Sbjct: 445  KCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTI 504

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            +WYK+G  + + + + I ++               +  YT EASN  G
Sbjct: 505  VWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 15/238 (6%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            +Q++K   + ++   A N   I  A  T E    +   K ++P     L+ +     +++
Sbjct: 242  LQDIKIKDAGQYECIASNP--IGKAFCTAE----MTVNKREAPVFVSKLRPLFVTEGDNV 295

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXXXXXX-XXXXXYKCIAFND 1555
               C   G+P+P V WYRD + L+     K  ++ R                Y C+  N 
Sbjct: 296  SWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNS 355

Query: 1556 HGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612
             G   +S  + + +K   P +     D++     G E        G+P PEV WY+N  K
Sbjct: 356  AGSAFSSAELQVDKKANKPKVIEKMNDVQTVE--GTEARFDVRFSGLPRPEVTWYRNSIK 413

Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
            + N+  ++++       + I + K   +  Y   A+N  G  +    L V ++   PE
Sbjct: 414  VRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLDVRERQFAPE 471



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 14/205 (6%)

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-N 1531
            + K  +PT    L+ I     +D +L+C   G PQP+V W+RD   +K +   KA+Y+ N
Sbjct: 10   QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 69

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---------PVITISNEDIKQ 1582
                            YKC+  N+ G V +   V + +K         P+          
Sbjct: 70   VSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPL 129

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            + +V     V+  + G P P V W+KNG +L + K   I +      + I   +   +  
Sbjct: 130  EIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGS 189

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS 1667
            Y   A N  G++     ++V ++PS
Sbjct: 190  YKCLARNDVGSAERLFEVQV-EEPS 213



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 1/97 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           ++++  P  +EK+    T +G+  +F+ +  G PRP++TW+R +  ++    F +  D D
Sbjct: 368 DKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGD 427

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              +L I +    D GT+ CVA N  G  +S  +L V
Sbjct: 428 RY-SLTITDTKLVDTGTYKCVATNEGGKITSRGDLDV 463



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 4/118 (3%)

Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
           ++ K D + V +K    E+  APIF EK  L P        V+    V G P+P +TW++
Sbjct: 97  VSSKAD-VTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWK 155

Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
               ++  +  ++        TL I     EDAG++ C+A+N  G A    E+ VE P
Sbjct: 156 NGKELRDGKHVEIR-SGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEP 212



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 36/169 (21%), Positives = 66/169 (39%), Gaps = 8/169 (4%)

Query: 1508 VPQPKVTWYRDGKKL---KTAKATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGEV--ET 1561
            V +P VTWYR+  ++     ++ T++                  Y+CIA N  G+     
Sbjct: 209  VEEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTA 268

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               V  ++ PV       +         W+    + G+P P V WY++   L  D  + +
Sbjct: 269  EMTVNKREAPVFVSKLRPLFVTEGDNVSWM--CKVAGMPRPTVEWYRDNQPLRADTRWKM 326

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
                +   + + E        Y    +N+AG++     L+V  K +KP+
Sbjct: 327  DFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPK 375



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%)

Query: 505 EQSMAPIFV---EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
           E+  AP F    E   P    +   + F+ +V G P P I W++   +++  + F++   
Sbjct: 465 ERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSR 524

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            D + T        EDAGT+TC A N  G
Sbjct: 525 GD-IYTFATYSASAEDAGTYTCEASNKLG 552



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 24/109 (22%), Positives = 53/109 (48%), Gaps = 3/109 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            GD++ ++  + G P PEV W+++   ++  + +  +     S + +KE +      Y   
Sbjct: 30   GDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCV 89

Query: 1647 ASNTAG--TSSVEVT-LKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             +N  G  +S  +VT LK + +P +   P+   +   E + I+ + P++
Sbjct: 90   VTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVE 138



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 8/126 (6%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518
            +S  ++ T   K ++  +  +P  E+   L+ +  +  + +E++    G P+P VTW+++
Sbjct: 97   VSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKN 156

Query: 1519 GKKLKTAKATYENRXXXXXXX-----XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
            GK+L+  K   E R                    YKC+A ND G  E    V +++  V 
Sbjct: 157  GKELRDGKHV-EIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEPSVT 215

Query: 1574 TISNED 1579
               N++
Sbjct: 216  WYRNKN 221


>UniRef50_O94856 Cluster: Neurofascin precursor; n=64;
           Euteleostomi|Rep: Neurofascin precursor - Homo sapiens
           (Human)
          Length = 1347

 Score =  126 bits (303), Expect = 9e-27
 Identities = 90/320 (28%), Positives = 149/320 (46%), Gaps = 24/320 (7%)

Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
           +Q V  G D+LLEC    +P PDIAW  KG ++  D+       +    +   L+ITNV 
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK-------AKFENFNKALRITNVS 307

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           +   G Y  +A N+ G     I +++K      P  ++  K++I+  GE   L  +  GN
Sbjct: 308 EEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGN 363

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENSEGIAETSAVI 820
           P+PT+ W  N +P+++ P   + +    TI+ +  ++    VY     N  G    +A +
Sbjct: 364 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 423

Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
           +V +       P +   R Q I V      +L      +P+P++ W++N +    S    
Sbjct: 424 SVLD-----VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ---GSNLDG 475

Query: 881 QNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
            N+   EN  L I  +  E D G Y CVA+N  GK+ +  +V ++V+  T +  + +   
Sbjct: 476 GNYHVYENGSLEIKMIRKE-DQGIYTCVATNILGKAEN--QVRLEVKDPTRIYRMPEDQV 532

Query: 940 TEEGKTVILECQTSHTVSTK 959
              G TV LEC+  H  S K
Sbjct: 533 ARRGTTVQLECRVKHDPSLK 552



 Score =  101 bits (242), Expect = 2e-19
 Identities = 121/520 (23%), Positives = 205/520 (39%), Gaps = 38/520 (7%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX---XXXXXXXX 1545
            KN+   P ED  L C   G P+P V W  +G+ L++A                       
Sbjct: 344  KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y+C   N+HG +  +  V +   P   +S  +   +  + +   +     G P P + 
Sbjct: 404  AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W+KNG     D   N    E  S + IK +++     YT  A+N  G +  +V L+V D 
Sbjct: 464  WFKNGQGSNLDGG-NYHVYENGS-LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDP 521

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPL-DDGGLELTKYAIEKHEP--DNNRWIKVAD---- 1718
                  P    +++R   T++ +  +  D  L+LT   ++  EP    NR  K  D    
Sbjct: 522  TRIYRMP--EDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTI 579

Query: 1719 ---VDRDVETY-CI--QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772
                +RD  +Y C+   +L+++    +  +  +    +  L + P   K   D P     
Sbjct: 580  FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALP---KGRPDRP----R 632

Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQK 1828
                  +   SV +TW P + N  SPI DY V+ +    Q G             + + +
Sbjct: 633  DLELTDLAERSVRLTWIPGDAN-NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR 691

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
            LS    YQFR+ A NE+G+S P    ++        P S P +     +   ++ + WT 
Sbjct: 692  LSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGA-PPESNPGDVKGEGTRKNNMEITWTP 750

Query: 1889 PESNGG-SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
              +     P   YI++++  + +     VTV GS +      +    EI  R+ AEN  G
Sbjct: 751  MNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEI--RVQAENDFG 808

Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
                 E +SV        P      +++R++ S  +   W
Sbjct: 809  KG--PEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQW 846



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 76/303 (25%), Positives = 123/303 (40%), Gaps = 31/303 (10%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV---PDENISVAIESDMHM 690
           P +  +PK   +  G D  L CR    P+P + W+  GE +    P+ N  VA ++    
Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT---- 392

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQG 749
              + + T +       Y     N  G       + +      PP+++ P   +I V   
Sbjct: 393 --IIFRDTQISS--RAVYQCNTSNEHGYLLANAFVSVLD---VPPRMLSPRNQLIRVILY 445

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
               L     G+P PT+ W KN +             +    +K  + +D+G+YT  A N
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505

Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT--W 866
             G AE    + V++PT         I R  E  V  +GT ++L  RV  +P   +T  W
Sbjct: 506 ILGKAENQVRLEVKDPTR--------IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557

Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            +++E +     I      E+  L I  V +E D G Y CVAS    +    A +T+  +
Sbjct: 558 LKDDEPLY----IGNRMKKEDDSLTIFGV-AERDQGSYTCVASTELDQDLAKAYLTVLAD 612

Query: 927 KVT 929
           + T
Sbjct: 613 QAT 615



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 132/604 (21%), Positives = 220/604 (36%), Gaps = 57/604 (9%)

Query: 633  PPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMH 689
            PPT +K+  K   VD   +IL+EC     P P   W        I  D  +S+   S   
Sbjct: 40   PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            +     +     +  EG Y   A N+ G A S  I L++      P + ++P   ++V++
Sbjct: 100  VI--DFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP---VVVQE 154

Query: 749  GESVILSAQ-VVGNPRPTITWCKNN-KPV---KALPTKSDGDTHSITILKPKKVKDEG-- 801
            G  + L      G P P I W  ++ +P+   K +    +GD +   ++      D    
Sbjct: 155  GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCN 214

Query: 802  -----VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
                  +T++ +N      T  V+T     E                V     + L    
Sbjct: 215  ARFHFTHTIQQKN----PFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            +  P P I WY+    +   +   +NF   N  L ITNV SE DSG+Y C+ASN  G   
Sbjct: 271  SGVPTPDIAWYKKGGDLPSDKAKFENF---NKALRITNV-SEEDSGEYFCLASNKMGSIR 326

Query: 917  HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHRE 974
            H   +++ V+   +     K+     G+   L C+ +     + +W  N + +       
Sbjct: 327  H--TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIR-KLQDFEVK 1029
              +E                 V +C   ++      +  + V +  P  +  + Q   V 
Sbjct: 385  -NREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVI 443

Query: 1030 EKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
              +   L+     S    + W ++G+        Y   + G +    IR     D+G Y+
Sbjct: 444  LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRK---EDQGIYT 500

Query: 1089 CILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKD 1142
            C+  +    AE  V   V+ P  I    ++Q   +G     E  +    +L   V W KD
Sbjct: 501  CVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560

Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINF 1198
               +   N ++   D     L I+     D G Y+C    E+      A LTV       
Sbjct: 561  DEPLYIGNRMKKEDD----SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATP 616

Query: 1199 TLRL 1202
            T RL
Sbjct: 617  TNRL 620



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 117/589 (19%), Positives = 215/589 (36%), Gaps = 45/589 (7%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            L C F G P P + W+++G+        Y                    Y C+A N  G+
Sbjct: 450  LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509

Query: 1559 VETSCVVGIQQKPVITISNED--------IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             E    + ++    I    ED        ++ + +V  +  +   +  +   E ++  N 
Sbjct: 510  AENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNR 569

Query: 1611 NKLENDKE--YNITTKEKTSV--IRIKELKRSHSSKY-TIEASNTAGTSSVEVTLKVYDK 1665
             K E+D    + +  +++ S   +   EL +  +  Y T+ A     T+ +    K   +
Sbjct: 570  MKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPK--GR 627

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WIKVADVDRDV 1723
            P +P   + + +++  SV + W P  D     +T Y ++  E       W   +     V
Sbjct: 628  PDRPRD-LELTDLAERSVRLTWIPG-DANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV 685

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782
             +  + +L+    Y FRVIA N VG S  +L SE    +T+   P               
Sbjct: 686  NS-AVLRLSPYVNYQFRVIAINEVGSSHPSLPSER--YRTSGAPPESNPGDVKGEGTRKN 742

Query: 1783 SVYITWFPSEKNGG-SPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRI 1839
            ++ ITW P        P + Y V+ ++   +  W            + +  +   Y+ R+
Sbjct: 743  NMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYV-VGQTPVYVPYEIRV 801

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             A N+ G   P   +  I       P + P    V    S +++L+W    S+    +  
Sbjct: 802  QAENDFGKG-P-EPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSD---TVQG 856

Query: 1900 YIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEI--IFRISAENTVGVSLPTESQ 1955
             + E++    +  S  K + V     +      + +  +  +F  S      V +     
Sbjct: 857  QLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGD 916

Query: 1956 SVRLE-KHATVP-SPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNI--AIRDVT 2009
              R E K  T P   P+AP   R+   N+  +   W  PE   G  ++GY +     + T
Sbjct: 917  GPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGI-MIGYTLKYVAFNGT 975

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
            K     V     N  KF ++       Y   + AR ++G  E +  + P
Sbjct: 976  KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1024



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 146/705 (20%), Positives = 255/705 (36%), Gaps = 79/705 (11%)

Query: 828  ENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
            E  +PP    +  ++  V  +  I +      NP PS  W RN+   + ++    +    
Sbjct: 36   ELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR 95

Query: 887  NIELVI---TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEE 942
            +  LVI   +    E   G+Y+C A N  G +    R+ + V K   + K        +E
Sbjct: 96   SGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSN-RIRLQVSKSPLWPKENLDPVVVQE 154

Query: 943  GKTVILECQTSHTVSTK---WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IK 998
            G  + L+C     + +    W  +  E    D R  + +G             D+     
Sbjct: 155  GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKR--VSQGHNGDLYFSNVMLQDMQTDYS 212

Query: 999  C--------IVKDQETSTMLV-----VKETIPEFI----RKLQDFEVKEKDVAILEVEIN 1041
            C         ++ +   T+ V     V E  P F+           ++  D+ +  +   
Sbjct: 213  CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
              T D+ W + G  +   K K++       + L I N S  D GEY C+  ++  +   T
Sbjct: 273  VPTPDIAWYKKGGDLPSDKAKFE----NFNKALRITNVSEEDSGEYFCLASNKMGSIRHT 328

Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157
            +   V+  P  +   +N  +  G                V+W  +G  +Q S       +
Sbjct: 329  ISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ-SAPPNPNRE 387

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAILTVEEPSINFTLRLPEFILVPA 1210
                 +   D  +     Y C   N       +   ++L V    ++   +L   IL   
Sbjct: 388  VAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNR 447

Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                      P  TL   W+K       D   + +  +      +IRK   +DQ  YTCV
Sbjct: 448  TRLDCPFFGSPIPTL--RWFKNGQGSNLDGGNYHVYENGSLEIKMIRK---EDQGIYTCV 502

Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNS 1325
              +   K+  ++++EV + P +I     +   +RG+ V L   V +    +    W+ + 
Sbjct: 503  ATNILGKAENQVRLEVKD-PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 561

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSP- 1383
            + +      K   DS    LTI  V   D G Y             +  +T+L D+ +P 
Sbjct: 562  EPLYIGNRMKKEDDS----LTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPT 617

Query: 1384 ----------PGKPNILEIDS---SSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWI 1428
                      P +P  LE+      S+ + W  P +  NS I  YVV+++E       W 
Sbjct: 618  NRLAALPKGRPDRPRDLELTDLAERSVRLTWI-PGDANNSPITDYVVQFEEDQFQPGVWH 676

Query: 1429 S-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
               K      +++  L    +Y+FR  A+NEV  S  S  +E Y+
Sbjct: 677  DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYR 721



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 79/403 (19%), Positives = 153/403 (37%), Gaps = 24/403 (5%)

Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            PP I     +++ +    ++ +  + +  P P+  W  NS+     K  + S+  +S +L
Sbjct: 40   PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99

Query: 1346 TIK-----KVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKPNILEI---DSSS 1396
             I      + E  + G Y+    N  G A    + + +   P  P K N+  +   + + 
Sbjct: 100  VIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSPLWP-KENLDPVVVQEGAP 157

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSYRFRA 1453
            + +  + P    +  I +     + I   + +S  +   +  +   +Q+++T+ S   R 
Sbjct: 158  LTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARF 217

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP---NEDIELTCIFGGVPQ 1510
            +  +   I   +  T      +    ++P+   P    +++      D+ L CI  GVP 
Sbjct: 218  HFTHT--IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275

Query: 1511 PKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            P + WY+ G  L + KA +EN                 Y C+A N  G +  +  V ++ 
Sbjct: 276  PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             P     +E        G++  +     G P P V W  NG  L++    N   +     
Sbjct: 336  APYWL--DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDT 392

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            I  ++ + S  + Y    SN  G       + V D P +   P
Sbjct: 393  IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 435



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 68/267 (25%), Positives = 110/267 (41%), Gaps = 28/267 (10%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923
            P +PR+  +++   RSV L W   ++N  SPIT+Y+++F+  + +   W       GSV+
Sbjct: 628  PDRPRDLELTDLAERSVRLTWIPGDAN-NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN 686

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA-PLEIRMVGS-- 1980
               +  +       FR+ A N VG S P    S+  E++ T  +PP + P +++  G+  
Sbjct: 687  S-AVLRLSPYVNYQFRVIAINEVGSSHP----SLPSERYRTSGAPPESNPGDVKGEGTRK 741

Query: 1981 NIVMTSWGTP--EWDGGAPLLGYNIA-IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037
            N +  +W TP        P L Y +   R  T+  W     V V   ++ +        Y
Sbjct: 742  NNMEITW-TPMNATSAFGPNLRYIVKWRRRETREAW---NNVTVWGSRYVVGQTPVYVPY 797

Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREH 2097
             IR+ A N+ G     +  EP  VI   G   D      TEV             W R +
Sbjct: 798  EIRVQAENDFG-----KGPEPESVIGYSGE--DYPRAAPTEVKVRVMNSTAISLQWNRVY 850

Query: 2098 N--MDADIRSYARGSLLRRDEYFFRIW 2122
            +  +   +R Y R    R       +W
Sbjct: 851  SDTVQGQLREY-RAYYWRESSLLKNLW 876



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC   G P P I W+++   + PS   +  +++ N A L I  V  ED+G + C
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDL-PSD--KAKFENFNKA-LRITNVSEEDSGEYFC 316

Query: 584 VAKNAAGFASSTTELIVEA 602
           +A N  G    T  + V+A
Sbjct: 317 LASNKMGSIRHTISVRVKA 335



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
           + +C   G P P + WF+       + D   Y+  +N  +L I+ +  ED G +TCVA N
Sbjct: 449 RLDCPFFGSPIPTLRWFKNGQ--GSNLDGGNYHVYEN-GSLEIKMIRKEDQGIYTCVATN 505

Query: 588 AAGFASSTTELIVEAP 603
             G A +   L V+ P
Sbjct: 506 ILGKAENQVRLEVKDP 521



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 28/110 (25%), Positives = 43/110 (39%), Gaps = 4/110 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE- 1924
            PS PR F V +    ++ L+W  PE   G  I  Y +++    G    K +    S ++ 
Sbjct: 932  PSAPRRFRVRQPNLETINLEWDHPEHPNGIMI-GYTLKYVAFNGTKVGKQIVENFSPNQT 990

Query: 1925 -HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAP 1972
               ++         F +SA   VG       +S      AT   +PPT P
Sbjct: 991  KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP 1040



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 5/88 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS--VKNITKTQT 1438
            PS P +  + + +  +IN+ WD PE+  N  +I Y ++Y   + T+     V+N +  QT
Sbjct: 932  PSAPRRFRVRQPNLETINLEWDHPEHP-NGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 990

Query: 1439 --SIQNLKTNSSYRFRAYAVNEVDISDA 1464
              ++Q     S YRF   A  +V   +A
Sbjct: 991  KFTVQRTDPVSRYRFTLSARTQVGSGEA 1018


>UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p -
            Drosophila melanogaster (Fruit fly)
          Length = 1006

 Score =  125 bits (302), Expect = 1e-26
 Identities = 175/829 (21%), Positives = 327/829 (39%), Gaps = 77/829 (9%)

Query: 648  GSDILLECRLVAIPEP--DIAWLFKGEEIV-PDEN------ISVAIESDMHMYCSVLKIT 698
            G+  L++C +     P   +A   +GEEI+ PD +      + +A   D+++  SV    
Sbjct: 152  GNSALIKCAIPEYVRPYVRVASWHRGEEILLPDLSDVAGRYVVLAASGDLYVR-SVRSED 210

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSA 756
             + KF         +N E + S  ++L++K   K   P    +P+  + V +G  V L  
Sbjct: 211  GLMKFS--CLVTNTLNGERQRSDAVMLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPC 268

Query: 757  QVVGNPRPTITWCKNNKPVKALPTKSDGD---THSITILKPKKVKDEGVYTLKAENSEGI 813
             + GNP P  TW + +      P  S      + ++ ++K    +D G +  +A N  G 
Sbjct: 269  NIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGE 328

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
                  ++V      +  P + I       V   GT       T + + +I W  N + +
Sbjct: 329  QRIEIRLSVNSYVSVHILPQVQI-------VNSGGTANFNCTTTGSAIDAIDWLHNGKPL 381

Query: 874  SPSETITQNFDG----ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
              +  +T   D         L++ NV    D G Y+C+  N    +   A + +  + V 
Sbjct: 382  QANNALTTGRDNIRFLSKSSLLVQNVGRR-DRGVYQCLVENQRASAQAMAELKLG-DTVP 439

Query: 930  FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEIS--GMDHREIIQE------G 979
             + +         G  + L+C  S +   +  W  + + I    + HR  I +       
Sbjct: 440  ELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGD 499

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQDFE-VKEKDVAIL 1036
                         D G+ KC+  +   S     +  +  P ++R +   + V  +D+ + 
Sbjct: 500  VISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGPIKAVAGEDIIVH 559

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV-HDEGEYSCILRD-- 1093
                      + WE+  + +    N Y+        +L I+N     D+G Y+CI+R   
Sbjct: 560  CPFAGYPVEQIRWEKAHQELTTS-NHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRA 618

Query: 1094 -ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFS 1149
             E    ++ + V  PP I      + + +G +A     ++ GD  +   W KD S I  S
Sbjct: 619  GEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSS 678

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-PEFILV 1208
              I    +     L   D     +G+Y+C   N+      T E       +R+ P +   
Sbjct: 679  LQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAKVNYTAE-----LQVRVAPRWRYE 733

Query: 1209 PANTDAYL--TVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261
            P +T   L  T+ I  E        +TW+K +   + ++ F  +S ++  +L++   T++
Sbjct: 734  PMDTAIMLGNTISINCEAEGYPIPTITWFKGQG--KGSKDFKPLS-MRNHSLLLNLATDN 790

Query: 1262 DQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
            D+  Y C     + A     +++ V E P +     R    +R   VTL    +      
Sbjct: 791  DEGYYMCQATNEIGAGLKKTIRINVNE-PARFEQSARNISSRRNDPVTLDCHAKGDEPIT 849

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS-----ASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
              W  N+  I          + K+     + LTI   +  D+G+Y+   EN  G A+  +
Sbjct: 850  IGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQII 909

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
             + + ++P  P    I E+ S ++ + W  P + GNS ++ Y+V+YQ +
Sbjct: 910  FLAVQERPDTPSHLEIFEVGSRTVKLSWRRPFD-GNSPVLSYLVQYQAL 957



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 135/607 (22%), Positives = 241/607 (39%), Gaps = 64/607 (10%)

Query: 627  DILEGIPPTFSKKPKAQ-YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
            ++ + + P  ++KP  + +V+ G+D+ L C +   P P   W       V D      I 
Sbjct: 239  ELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYR-----VSDSAALYPIP 293

Query: 686  SDMHMYCS--VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPL 741
            S   +  S  +L I N  +   G +   A N+ GE  + I L + +       PQV    
Sbjct: 294  SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQV---- 349

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD---THSITILKPK 795
               IV  G +   +    G+    I W  N KP++A   L T  D     + S  +++  
Sbjct: 350  --QIVNSGGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNV 407

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
              +D GVY    EN    A+  A + + +   E       I  F E  V+    I L   
Sbjct: 408  GRRDRGVYQCLVENQRASAQAMAELKLGDTVPE------LIYTFIEQNVRPGPLISLKCS 461

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIEL---VITNVD-SEI---DSGDYKCVA 908
             + +P P   W  +++ I       +   G+ +++   VI++++ S +   D G YKCVA
Sbjct: 462  ASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVA 521

Query: 909  SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTV-STKWYHNKKE 966
            SNS G   H AR  ++V    +V+ +    +   G+ +I+ C    + V   +W    +E
Sbjct: 522  SNSMGSVQHSAR--LNVYGPPYVRAI-GPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQE 578

Query: 967  ISGMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIR 1021
            ++  +H E+  + +G             D G+  CIV+    +E    + +    P  I 
Sbjct: 579  LTTSNHYELASVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIE 637

Query: 1022 KLQ-DFEVKEKDVAILEVEINSETADVV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
              +    ++E   A +   ++S    +   W++D   I P   +   +K      L  ++
Sbjct: 638  PFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSI-PSSLQITEKKEEFYSLLVFKD 696

Query: 1079 TSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
             S    G+Y+C   + +     T    V + P       +  +  GN  +   E  +G  
Sbjct: 697  ISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCE-AEGYP 755

Query: 1136 L--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAI 1188
            +  + WFK G      +   L++  +   L +     +D G Y C+  N      K T  
Sbjct: 756  IPTITWFK-GQGKGSKDFKPLSM--RNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIR 812

Query: 1189 LTVEEPS 1195
            + V EP+
Sbjct: 813  INVNEPA 819



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 130/664 (19%), Positives = 237/664 (35%), Gaps = 48/664 (7%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130
            L I+N    D G++ C   ++     + +   V     +    Q Q VN G  A F    
Sbjct: 305  LLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTT 364

Query: 1131 TKGDAL--VRWFKDGSEIQFSNHIQLTIDG----KKQKLKIYDCDLDDAGEYSCEVGNSK 1184
            T G A+  + W  +G  +Q +N +    D      K  L + +    D G Y C V N +
Sbjct: 365  T-GSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQR 423

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-----DVTWYKKKSVIEDT 1239
             +A   + E  +  T+    +  +  N      + +             W      I D 
Sbjct: 424  ASA-QAMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDV 482

Query: 1240 E--------KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
                     +F  +S      L I     DD   Y CV  ++  + +    +  + P  V
Sbjct: 483  SLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYV 542

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                  +   G D+ +   +  +P     W    + +    H + +  +    L IK VE
Sbjct: 543  RAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVE 602

Query: 1352 -NTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
               D GIY   + +  G     D+++NV       P   P  L+    +   C     ++
Sbjct: 603  PGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITC---AVSS 659

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
            G+  I +    +++ D++   S++ IT+ +    +L        R         S+A+  
Sbjct: 660  GDMPIYF---SWKKDDSSIPSSLQ-ITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAK 715

Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAK 1526
              Y   + + ++      +P+       N  I + C   G P P +TW++  GK  K  K
Sbjct: 716  VNYTAEL-QVRVAPRWRYEPMDTAIMLGNT-ISINCEAEGYPIPTITWFKGQGKGSKDFK 773

Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHK 1585
                                 Y C A N+ G  ++ +  + + +      S  +I  +  
Sbjct: 774  PLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRR- 832

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNI----TTKEKTSVIRIKELKRSHS 1640
              D   +    +G  P  + W +N  +++ N+  ++I    T K   S + I    R  S
Sbjct: 833  -NDPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDS 891

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
              Y   A N  G +   + L V ++P  P    I  E+   +V + W+ P  DG   +  
Sbjct: 892  GVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIF-EVGSRTVKLSWRRPF-DGNSPVLS 949

Query: 1701 YAIE 1704
            Y ++
Sbjct: 950  YLVQ 953



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 100/471 (21%), Positives = 173/471 (36%), Gaps = 50/471 (10%)

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRX 1533
            +  P   + +  I     EDI + C F G P  ++ W +  ++L T+      +  +   
Sbjct: 536  VYGPPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQ 595

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                          Y CI  +  GE       + +   PVI       K   + G   + 
Sbjct: 596  LVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFP-KNLQEGGRAQIT 654

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             AV  G  P    W K+ + + +  +     +E  S++  K++   HS KYT  ASN A 
Sbjct: 655  CAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA 714

Query: 1653 TSSVEVTLKVYDKPS---KPEGPVIMR----EISRESV-----TIEWKPPLDDGGLELTK 1700
              +    L+V   P    +P    IM      I+ E+      TI W      G  +   
Sbjct: 715  KVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKP 774

Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE---NCEYMFRVIAQNPVGFSEALESEP 1757
             ++  H    +  + +A  D D   Y  Q  NE     +   R+    P  F ++  +  
Sbjct: 775  LSMRNH----SLLLNLA-TDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARN-- 827

Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXX 1817
              I +  + P             +E + I W  ++ NG   + +++  I  E K  K   
Sbjct: 828  --ISSRRNDPVTLDCHAKG----DEPITIGW--TQNNGRIDLNNFRFSIA-EMKTEKGVD 878

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                    I     + +  +R  A N      PY   ++I        P  P +  + E 
Sbjct: 879  SQLT----IGHSDRHDSGVYRCIAEN------PYGRAEQIIFLAVQERPDTPSHLEIFEV 928

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSVHEHCI 1927
             SR+V L W  P  +G SP+ +Y+++++ +K  +S   +   GG  + H I
Sbjct: 929  GSRTVKLSWRRP-FDGNSPVLSYLVQYQALKYLQSHGSLAAAGGDWNGHVI 978



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 71/295 (24%), Positives = 119/295 (40%), Gaps = 34/295 (11%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP        + + EG    + C + +   P      K +  +P    S+ I      + 
Sbjct: 633 PPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPS---SLQITEKKEEFY 689

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           S+L   ++     G YT  A N   + +    L+++     P    EP+ + I+  G ++
Sbjct: 690 SLLVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVA---PRWRYEPMDTAIML-GNTI 745

Query: 753 ILSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            ++ +  G P PTITW K     +K  K L  ++    HS+ +L      DEG Y  +A 
Sbjct: 746 SINCEAEGYPIPTITWFKGQGKGSKDFKPLSMRN----HSL-LLNLATDNDEGYYMCQAT 800

Query: 809 NSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
           N  G      + I V EP         F    + I+ +    + L      +   +I W 
Sbjct: 801 NEIGAGLKKTIRINVNEPAR-------FEQSARNISSRRNDPVTLDCHAKGDEPITIGWT 853

Query: 868 RNNEII-------SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
           +NN  I       S +E  T+   G + +L I + D   DSG Y+C+A N  G++
Sbjct: 854 QNNGRIDLNNFRFSIAEMKTEK--GVDSQLTIGHSDRH-DSGVYRCIAENPYGRA 905



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 17/236 (7%)

Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
           H  + T             A++   + P +  +P    +  G+ I + C     P P I 
Sbjct: 701 HSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTIT 760

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
           W FKG+     +   +++ +  H     L   N     EG Y   A N  G A L   ++
Sbjct: 761 W-FKGQGKGSKDFKPLSMRN--HSLLLNLATDN----DEGYYMCQATNEIG-AGLKKTIR 812

Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALP 779
           I   E  P +  +  +++  R+ + V L     G+   TI W +NN  +           
Sbjct: 813 INVNE--PARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAE 870

Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
            K++    S   +      D GVY   AEN  G AE    + V+E  +  +   +F
Sbjct: 871 MKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIF 926



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 4/67 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+T+   C+ EGYP P ITWF+     K S+DF+     ++  +L++      D G + C
Sbjct: 742 GNTISINCEAEGYPIPTITWFKGQG--KGSKDFKPLSMRNH--SLLLNLATDNDEGYYMC 797

Query: 584 VAKNAAG 590
            A N  G
Sbjct: 798 QATNEIG 804



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 3/96 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P +V  + P     G  +   C   GYP  QI W +    +  S  +++    D    LV
Sbjct: 539 PPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADG-GQLV 597

Query: 570 IREVFP-EDAGTFTCVAKNAAG-FASSTTELIVEAP 603
           I+ V P  D G +TC+ ++ AG  A    +L V +P
Sbjct: 598 IKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSP 633



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 5/105 (4%)

Query: 506 QSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQDFQMYYDD 562
           +++AP   +K +   H   G+ V   C ++G P P  TW+R   +A + P    Q     
Sbjct: 242 KNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILS 301

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
             +  L+I+     DAG + C A N  G       L V + +S H
Sbjct: 302 RTL--LLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVH 344



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 13/90 (14%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----------DDDNVATLVIREV 573
           G  +  +C   G P PQ  W   +   +P  D  +++            D ++ L I  V
Sbjct: 453 GPLISLKCSASGSPPPQFAWLLDS---QPIMDVSLHHRFAIGQFVDMSGDVISHLNISHV 509

Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            P+D G + CVA N+ G    +  L V  P
Sbjct: 510 RPDDGGLYKCVASNSMGSVQHSARLNVYGP 539



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 509 APIFVEKLR-PKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVA 566
           +P  +E  + PK+  +G   Q  C V     P   +W +  + I PS        ++  +
Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSI-PSSLQITEKKEEFYS 690

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            LV +++    +G +TC A NAA   + T EL V
Sbjct: 691 LLVFKDISARHSGKYTCYASNAAAKVNYTAELQV 724



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 23/123 (18%)

Query: 1882 VTLKWTEPESNGGSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938
            +T+ WT+  +NG   + N+   I E KT KG      +T+G S            D  ++
Sbjct: 848  ITIGWTQ--NNGRIDLNNFRFSIAEMKTEKGVD--SQLTIGHS---------DRHDSGVY 894

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998
            R  AEN  G +     Q + L       +P  + LEI  VGS  V  SW  P +DG +P+
Sbjct: 895  RCIAENPYGRA----EQIIFLAVQERPDTP--SHLEIFEVGSRTVKLSWRRP-FDGNSPV 947

Query: 1999 LGY 2001
            L Y
Sbjct: 948  LSY 950


>UniRef50_UPI000066030F Cluster: Myomesin-2 (M-protein) (165 kDa
            titin-associated protein) (165 kDa connectin-associated
            protein).; n=2; Takifugu rubripes|Rep: Myomesin-2
            (M-protein) (165 kDa titin-associated protein) (165 kDa
            connectin-associated protein). - Takifugu rubripes
          Length = 1351

 Score =  124 bits (299), Expect = 3e-26
 Identities = 108/421 (25%), Positives = 171/421 (40%), Gaps = 16/421 (3%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE 1724
            P +P   V   EI R  + + WKPP   G   L  Y IEK       W +V   +     
Sbjct: 368  PGEPTN-VHASEIFRSYIVLSWKPPSPRGRAPLW-YVIEKCLAGTGAWQRVNTGIQLLAP 425

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNES 1783
             Y +  L +  +Y FRV + N  G SEA E    + K  LD VPS              S
Sbjct: 426  RYPVFDLQDGQKYQFRVYSVNMYGSSEASEPSESIQKVNLDGVPSAPGHVVATRN-SKSS 484

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840
            V++ W  S+      ++ Y ++ +  G K W           R  +  L    +Y FR+ 
Sbjct: 485  VFVQWEASKHPKN--LMGYYIDGRVVGAKDWFPCNHKPFKQNRFVVHGLVPGESYVFRVQ 542

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N  G S        I++   L  PS P    +      S+TL W  P+  GGS I  Y
Sbjct: 543  AVNVFGLSEESQESTPISVEPALATPSAPYGITMLNCDGSSITLAWKSPKHCGGSKINAY 602

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             I+ + V    W ++     +     ++++ E     F++ A N  GV LP+        
Sbjct: 603  YIDKRDVDSLVWKEVNQEAVTERIFTVDSLIEGTFYEFKVQAANMAGVGLPSVPSLPMKC 662

Query: 1961 KHATVPSP-PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
               T+  P P   L    V S+ ++  W  P + G + + GY + +     + +  + + 
Sbjct: 663  VAWTMEEPGPAYDLSFSEVRSHSLVFLWKAPVYYGMSAITGYYVDMAKKGLSEFETLNQE 722

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF--KVIPGEG---SHADEEPG 2074
             V+     +  L E  +Y+ R+ A N +G+ +P E  +P   K +PG     +  DEE G
Sbjct: 723  PVSHRYLQVTGLEEGQSYVFRVRAVNSVGVGKPSEVSDPVCAKALPGTKEIVASVDEETG 782

Query: 2075 E 2075
            +
Sbjct: 783  D 783



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 64/277 (23%), Positives = 112/277 (40%), Gaps = 34/277 (12%)

Query: 1227 VTWYKKKSVIEDTE---KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK--STTKLKV 1281
            V WYK+   ++      K+ + S     +L+I +C   D  EY+ V  ++   +T+K  V
Sbjct: 38   VKWYKEGVPVDPLSTPGKYKIESKYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATV 97

Query: 1282 EV---------------VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ-----PNDEW 1321
             V               V+    ++D+        G  ++L+      P      P  +W
Sbjct: 98   IVKSKKLFFLLCHSDVFVKLEVTLIDHFPVSFGVEGDSISLVCSMVVVPNLPNLPPLAQW 157

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-K 1380
              + K++K  K  + S+   +A LT+  +   D G+Y LR+    G  +    + + D  
Sbjct: 158  YRDDKLLKPNKFVEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDGSTEHSAYLFVSDAA 217

Query: 1381 PSPPGKP------NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-- 1432
            PS  G P         +I+S  + I W  P     + II Y V+  E  +  W+   +  
Sbjct: 218  PSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSDTWVQCNDSP 277

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            +   +  +  LK   +Y FR  AVN   IS  S  ++
Sbjct: 278  VNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSD 314



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 73/299 (24%), Positives = 121/299 (40%), Gaps = 34/299 (11%)

Query: 1499 IELTCIFGGVPQPKVTWYRDG---KKLKT-AKATYENRXXXXXXXXXX---XXXXXYKCI 1551
            I+L C   G P+P V WY++G     L T  K   E++                  Y  +
Sbjct: 24   IKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIESKYGVHSLVISRCAVSDTAEYSAV 83

Query: 1552 AFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVG--DEWLVTAVIEG---------- 1598
            A N HG   +   V ++ K +   + + D+  K +V   D + V+  +EG          
Sbjct: 84   ATNSHGMATSKATVIVKSKKLFFLLCHSDVFVKLEVTLIDHFPVSFGVEGDSISLVCSMV 143

Query: 1599 -IP-----PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             +P     PP   WY++   L+ +K   ++     + + +  L +     YT+      G
Sbjct: 144  VVPNLPNLPPLAQWYRDDKLLKPNKFVEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDG 203

Query: 1653 TSSVEVTLKVYDK-PS---KPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKH 1706
            ++     L V D  PS    P  P+ ++  +I+ + V I WKPP       +  Y +++ 
Sbjct: 204  STEHSAYLFVSDAAPSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRC 263

Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
            E  ++ W++  D   +V  Y +  L     Y FRV A N  G S        V  TALD
Sbjct: 264  EAGSDTWVQCNDSPVNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSDKV--TALD 320



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 6/203 (2%)

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGS 1921
            +T P +P N   SE     + L W  P   G +P+  Y+IE       +W ++ T +   
Sbjct: 365  VTIPGEPTNVHASEIFRSYIVLSWKPPSPRGRAPLW-YVIEKCLAGTGAWQRVNTGIQLL 423

Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGS 1980
               + + ++++  +  FR+ + N  G S  +E S+S++      VPS P   +  R   S
Sbjct: 424  APRYPVFDLQDGQKYQFRVYSVNMYGSSEASEPSESIQKVNLDGVPSAPGHVVATRNSKS 483

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + V   W   +      L+GY I  R V    W           +F +  L    +Y+ R
Sbjct: 484  S-VFVQWEASKHPKN--LMGYYIDGRVVGAKDWFPCNHKPFKQNRFVVHGLVPGESYVFR 540

Query: 2041 IYARNEIGLSEPLESDEPFKVIP 2063
            + A N  GLSE  +   P  V P
Sbjct: 541  VQAVNVFGLSEESQESTPISVEP 563



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 42/187 (22%), Positives = 83/187 (44%), Gaps = 10/187 (5%)

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            P+  +  + K +K   + ++ +VGG      + ++ + DE ++ +      G    TE  
Sbjct: 153  PLAQWYRDDKLLKPNKFVEM-SVGGGAARLTLPHLAKDDEGLYTLRVFTKDG---STEHS 208

Query: 1956 SVRLEKHA--TVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
            +      A  +V   P AP+ ++   + S+ V+ +W  P     AP++GY +   +    
Sbjct: 209  AYLFVSDAAPSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSD 268

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071
             W++     VN  K+ +  L   HTY  R+ A N  G+S P    +  KV   + + +++
Sbjct: 269  TWVQCNDSPVNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSD--KVTALDTAESEK 326

Query: 2072 EPGEQTE 2078
              G + E
Sbjct: 327  LQGTEEE 333



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 47/220 (21%), Positives = 92/220 (41%), Gaps = 23/220 (10%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           +E    P F+  LRP    + + ++  C V+G PRP + W+++   + P      Y  + 
Sbjct: 1   DEVPKMPDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIES 60

Query: 564 --NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
              V +LVI      D   ++ VA N+ G A+S   +IV++       ++          
Sbjct: 61  KYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATVIVKS------KKLFFLLCHSDVF 114

Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE----PDIAWLFKGEEIVPD 677
                 +++  P +F          EG  I L C +V +P     P +A  ++ ++++  
Sbjct: 115 VKLEVTLIDHFPVSFGV--------EGDSISLVCSMVVVPNLPNLPPLAQWYRDDKLLKP 166

Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
                 +E  +    + L + ++ K  EG YT+    ++G
Sbjct: 167 NKF---VEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDG 203



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 22/205 (10%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT------KSDGDTHS 788
           P  I  L+   V +   + L   V GNPRP + W K   PV  L T      +S    HS
Sbjct: 7   PDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIESKYGVHS 66

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP------TEENAEPPLFINRFQEI 842
           + I +   V D   Y+  A NS G+A + A + V+           +    L +      
Sbjct: 67  LVISR-CAVSDTAEYSAVATNSHGMATSKATVIVKSKKLFFLLCHSDVFVKLEVTLIDHF 125

Query: 843 TVK---EKGTIKLVARVT-----RNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894
            V    E  +I LV  +       N  P   WYR+++++ P++ +  +  G    L + +
Sbjct: 126 PVSFGVEGDSISLVCSMVVVPNLPNLPPLAQWYRDDKLLKPNKFVEMSVGGGAARLTLPH 185

Query: 895 VDSEIDSGDYKCVASNSAGKSSHGA 919
           +  + D G Y        G + H A
Sbjct: 186 LAKD-DEGLYTLRVFTKDGSTEHSA 209



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 52/286 (18%), Positives = 108/286 (37%), Gaps = 8/286 (2%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435
            L  PS P    +L  D SSI + W  P++ G S I  Y ++ +++D+  W  ++ + +T+
Sbjct: 565  LATPSAPYGITMLNCDGSSITLAWKSPKHCGGSKINAYYIDKRDVDSLVWKEVNQEAVTE 624

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494
               ++ +L   + Y F+  A N   +   S  +   K +  T  +  P  +     + + 
Sbjct: 625  RIFTVDSLIEGTFYEFKVQAANMAGVGLPSVPSLPMKCVAWTMEEPGPAYDLSFSEVRSH 684

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXXXXXXXXXXYKC 1550
                +    ++ G+      +    KK     +T      +                ++ 
Sbjct: 685  SLVFLWKAPVYYGMSAITGYYVDMAKKGLSEFETLNQEPVSHRYLQVTGLEEGQSYVFRV 744

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
             A N  G  + S V        +  + E +     + GD +L     E     + +W KN
Sbjct: 745  RAVNSVGVGKPSEVSDPVCAKALPGTKEIVASVDEETGDIYLSLEACEISETSKFVWSKN 804

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
               +      ++T K +TS +      +    +Y++  ++T G S+
Sbjct: 805  YKPIGECPRVSVTAKGRTSRLTFTNPDKDDLGRYSVVVTDTDGVSA 850



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 19/65 (29%), Positives = 37/65 (56%)

Query: 526  TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            ++   C V G P P++TWF+    +  ++  ++ +D    A+LVI +V P+D+G ++   
Sbjct: 1271 SLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINV 1330

Query: 586  KNAAG 590
            +N  G
Sbjct: 1331 RNKYG 1335



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%)

Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ-NFDG 885
           +E  + P FI   +  TV EK  IKL   V  NP P + WY+    + P  T  +   + 
Sbjct: 1   DEVPKMPDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIES 60

Query: 886 E-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
           +  +  ++ +  +  D+ +Y  VA+NS G ++  A V +  +K+ F+
Sbjct: 61  KYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATVIVKSKKLFFL 107



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 2/86 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +T+ E+ ++ L   V   P P +TW++N + +  +E     FDG     ++ N  +  DS
Sbjct: 1264 VTIMEEKSLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDS 1323

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEK 927
            G Y     N  G       +T+ V K
Sbjct: 1324 GKYSINVRNKYG--GEFVEITVSVYK 1347



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 1/73 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  + G P PEV W+KN  ++ +++   +T    K + + I ++    S KY+I   N 
Sbjct: 1274 LTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRNK 1333

Query: 1651 AGTSSVEVTLKVY 1663
             G   VE+T+ VY
Sbjct: 1334 YGGEFVEITVSVY 1346



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
            P P   W  N + +   +HT+ + D  K ASL I KV   D+G Y + + N  G   VE+
Sbjct: 1282 PTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRNKYGGEFVEI 1341

Query: 1374 NVTI 1377
             V++
Sbjct: 1342 TVSV 1345



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P  P   +  EI  S I + W  P   G + + +YV+E     T  W  V     +   +
Sbjct: 368  PGEPTNVHASEIFRSYIVLSWKPPSPRGRAPL-WYVIEKCLAGTGAWQRVNTGIQLLAPR 426

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
              + +L+    Y+FR Y+VN    S+ASE +E
Sbjct: 427  YPVFDLQDGQKYQFRVYSVNMYGSSEASEPSE 458



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835
            I+++ V I W P      +PII Y V+  + G   W           +  +  L +  TY
Sbjct: 235  INSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSDTWVQCNDSPVNVCKYPVHGLKVGHTY 294

Query: 1836 QFRIYARNEIGTSLPYTSDDKIT 1858
             FR+ A N  G S P    DK+T
Sbjct: 295  HFRVRAVNSAGISRPSRKSDKVT 317



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 4/102 (3%)

Query: 731  EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDT 786
            EK   +V+  L  ++ + + +S+ L+  V G P P +TW KN + V   +      DG  
Sbjct: 1250 EKNRGRVVGGLPDVVTIMEEKSLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGK 1309

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
             +  ++      D G Y++   N  G       ++V +  E+
Sbjct: 1310 FASLVINKVTPDDSGKYSINVRNKYGGEFVEITVSVYKHGEQ 1351



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGN 1182
            V WFK+  E+  + H ++T DG K   L I     DD+G+YS  V N
Sbjct: 1286 VTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRN 1332


>UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
            SCAF15039, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1702

 Score =  123 bits (297), Expect = 5e-26
 Identities = 162/720 (22%), Positives = 259/720 (35%), Gaps = 60/720 (8%)

Query: 494  KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
            +L V+ +P S  +       E LR   T +G      C+V   P P ITW ++  +I P 
Sbjct: 865  QLTVYVRPRSNAEGPGSS-AEPLRMSVT-EGEDAILPCEVHSVPPPTITWAKER-LISP- 920

Query: 554  QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------- 605
              F   +      ++ I E    D+G + CVA N AG  + +  L V  P S        
Sbjct: 921  --FAPRHHPLPSCSMKILESKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGPRVM 978

Query: 606  ----DHGSEMTVXXXX----XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
                 H  E+                    ++E + P F+   + +  ++   I   C  
Sbjct: 979  KVQVGHPVELPCMVSGVPEPTLTWTRDVPPVVEVLEPPFNSPLQERVANQR--IAFPCPA 1036

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
              +P+P I WL  G+E+  +E   V+I  D     ++L + +V     G Y   A N  G
Sbjct: 1037 KGLPKPVIRWLRNGQELTGNEP-GVSILEDG----TLLLLASVSPLDSGEYVCAAANDAG 1091

Query: 718  EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
                   LK+          +    S+++ Q  S++    V G+P P ITW K   PV A
Sbjct: 1092 STERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSLV--CDVTGSPSPVITWYKEEMPVVA 1149

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
                   D      L      D G Y+ KA N  G AE    + V  P            
Sbjct: 1150 SDNVQILDMGKTLRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGS-----G 1204

Query: 838  RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
               +        I L  +V   P P+I WY++ + +   +    N +  N   ++    +
Sbjct: 1205 SSHDTVAMVTQEISLECKVEGLPFPTIQWYKDRKQVFLGD---PNLEVTNRGQILRIKSA 1261

Query: 898  EI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT- 955
             + D   Y+C   N+AGK S    +++ V       +         G  V LEC+     
Sbjct: 1262 RLGDKARYQCSVMNTAGKESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVP 1321

Query: 956  -VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014
              +  WY N + I      +  + GR                 K       T     +  
Sbjct: 1322 PPTVTWYRNGQAILSGRQTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDV 1381

Query: 1015 TIPEFIRKLQDFEVKEKDVA-----ILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKR 1068
             +P  I K  D    E+ V      ILE E        + W +DG  ++  ++    E  
Sbjct: 1382 YLPPTI-KGDDAGPTERKVVLSASLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELG 1440

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEI--ITRLQNQKVNKGNK 1123
            G   K+ I + ++ D G Y C+    +   EV     V +PP I     + +  V   + 
Sbjct: 1441 G---KIEISSATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHP 1497

Query: 1124 ATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
               E + T     +V W+KDG  IQ     ++   G  Q+L +    + D   + C   N
Sbjct: 1498 LEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGG--QRLLVSRAQISDTARFQCVAAN 1555



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 104/450 (23%), Positives = 179/450 (39%), Gaps = 41/450 (9%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V   C   GYP P++ W      +K S   +M  D      L IR    +D G + C
Sbjct: 480 GDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPD----GMLAIRNTEQKDGGVYRC 535

Query: 584 VAKNAAGFASSTTELI-VEAPLSDHG-SEMTVXXXXXXXXXXXXADILEG------IPPT 635
           +A N AG  ++ + L  +E+P+      ++ V            +   +         P 
Sbjct: 536 LASNQAGTDATNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAAPE 595

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           F+++P     D GS++ L C +   P+P + W  + ++ +P  N      S +      L
Sbjct: 596 FTREPSDTASDIGSNVTLWCLVRGYPDPQVTW--RRQDGLPPFNRPRTYGS-VTQSRRGL 652

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
             T++    E  Y   A N  G+      + + TG   P     P    +V      +  
Sbjct: 653 HFTHLWVEDEAVYVCEAHNHFGKIEAKARITV-TGLVLPVIARSPSVLSVVEDQPVTLPC 711

Query: 756 AQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             + GNP P   W  N   V   + +  + DG  H    ++  ++   G YT  AEN  G
Sbjct: 712 VLLAGNPLPARQWLHNYGLVTTDQYVKVRKDGSLH----IERVRLDHVGDYTCLAENVVG 767

Query: 813 IAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
           +   +  + V   PT ++  P +F          E   + L  R    P P ITW +  +
Sbjct: 768 LYNHTTTLNVYVIPTIQHG-PQVF-------NTIEGTPVTLPCRAIGVPSPEITWTKEGK 819

Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
           ++        +F  ++   +  N  S  +SG++ C+A+N+AG +S   ++T+ V   +  
Sbjct: 820 LLYLG---GPDFFLDSDGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNA 876

Query: 932 KHLQKSYE-----TEEGKTVILECQTSHTV 956
           +    S E       EG+  IL C+  H+V
Sbjct: 877 EGPGSSAEPLRMSVTEGEDAILPCEV-HSV 905



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 71/276 (25%), Positives = 117/276 (42%), Gaps = 19/276 (6%)

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
            L +E    DH  + T               +   + PT    P+     EG+ + L CR 
Sbjct: 745  LHIERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRA 804

Query: 658  VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
            + +P P+I W  +G +++        ++SD  ++     I +    + G +  +A N  G
Sbjct: 805  IGVPSPEITWTKEG-KLLYLGGPDFFLDSDGSLF-----INSPSGNESGEFICMATNAAG 858

Query: 718  EAS----LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
             AS    L + ++ ++  + P    EPL+ M V +GE  IL  +V   P PTITW K   
Sbjct: 859  HASRRVQLTVYVRPRSNAEGPGSSAEPLR-MSVTEGEDAILPCEVHSVPPPTITWAKERL 917

Query: 774  PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
                 P      + S+ IL+  KV D G+Y   A N  G    S +++V  P      P 
Sbjct: 918  ISPFAPRHHPLPSCSMKILE-SKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGP- 975

Query: 834  LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
                R  ++ V     ++L   V+  P P++TW R+
Sbjct: 976  ----RVMKVQVGH--PVELPCMVSGVPEPTLTWTRD 1005



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 78/258 (30%), Positives = 111/258 (43%), Gaps = 41/258 (15%)

Query: 520  HTPDGSTVQFECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATLVIREVFPEDA 578
            +T +G+ V   C+  G P P+ITW ++  ++     DF  + D D   +L I      ++
Sbjct: 791  NTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDF--FLDSDG--SLFINSPSGNES 846

Query: 579  GTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
            G F C+A NAAG AS   +L V   P S+                       EG  P  S
Sbjct: 847  GEFICMATNAAGHASRRVQLTVYVRPRSN----------------------AEG--PGSS 882

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
             +P    V EG D +L C + ++P P I W  K   I P       + S     CS +KI
Sbjct: 883  AEPLRMSVTEGEDAILPCEVHSVPPPTITWA-KERLISPFAPRHHPLPS-----CS-MKI 935

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
               K    G Y  VA N  G  +L ++L +      PP +    + M V+ G  V L   
Sbjct: 936  LESKVSDSGIYVCVASNIAGNLTLSVLLSVLV----PPSIQPGPRVMKVQVGHPVELPCM 991

Query: 758  VVGNPRPTITWCKNNKPV 775
            V G P PT+TW ++  PV
Sbjct: 992  VSGVPEPTLTWTRDVPPV 1009



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 112/575 (19%), Positives = 229/575 (39%), Gaps = 38/575 (6%)

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VEL 1105
            W R+G+ +   +      + G +  L + + S  D GEY C   +++ + E      V +
Sbjct: 1046 WLRNGQELTGNEPGVSILEDGTL--LLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNV 1103

Query: 1106 PPEIITRLQNQKVNK--GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            PP+      ++ V+       +   ++T   + ++ W+K+   +  S+++Q+   GK   
Sbjct: 1104 PPDFTDNEVSRNVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQILDMGKT-- 1161

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFI-LVPANTDAYL 1216
            L++   D  D+G YSC+  N   +A     +  +  P+I  +    + + +V        
Sbjct: 1162 LRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISLEC 1221

Query: 1217 TVE-IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
             VE +P  T+   WYK +  +   +    +++ + + L I+     D+  Y C +++   
Sbjct: 1222 KVEGLPFPTIQ--WYKDRKQVFLGDPNLEVTN-RGQILRIKSARLGDKARYQCSVMNTAG 1278

Query: 1276 TTKLKVEV-VEFPPKIVDYEREYRIKR--GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
                   + V  PP I        +    G+ VTL  + +  P P   W  N + I   +
Sbjct: 1279 KESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGR 1338

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNI 1389
             T+ +   +   L I +V+ TDAG Y  +  +  G  +    + +   P+  G    P  
Sbjct: 1339 QTQYT--ERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTE 1396

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
             ++  S+  I   E       ++ + + +   +  ++ + V  +   +  I +   + S 
Sbjct: 1397 RKVVLSASLILECEAGGRPPPSLTW-LKDGVPVRHSQSLRVLELGG-KIEISSATLSDSG 1454

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
            R+   A +   ++   E      V+    IQ   V   + + T   N  +E+ C   G P
Sbjct: 1455 RYVCVATS---VAGEKEVKYDVTVLVPPFIQGAGV---ITHSTVIINHPLEMECQATGTP 1508

Query: 1510 QPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             P VTWY+DGK ++  +                       ++C+A N+ G+++    V +
Sbjct: 1509 TPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDFTVVV 1568

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
             + P +  + + I Q    G    +     G P P
Sbjct: 1569 HEPPSVPHAGDVINQTILAGFSTQLECKATGTPLP 1603



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 111/560 (19%), Positives = 216/560 (38%), Gaps = 34/560 (6%)

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191
            ++RW ++G E+   N   ++I      L +      D+GEY C    + G+++    L V
Sbjct: 1043 VIRWLRNGQELT-GNEPGVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTERKYQLKV 1101

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVKK 1250
              P       +   + +  +    L  ++      V TWYK++  +  ++   ++ D+ K
Sbjct: 1102 NVPPDFTDNEVSRNVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQIL-DMGK 1160

Query: 1251 RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTL 1307
             TL + K    D   Y+C  ++ A S  K     V  PP I      +        +++L
Sbjct: 1161 -TLRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISL 1219

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
                +  P P  +W  + K +         + ++   L IK     D   Y+  + N  G
Sbjct: 1220 ECKVEGLPFPTIQWYKDRKQVF-LGDPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAG 1278

Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG--NSTIIYYVVEYQEIDTT 1425
                + N+++   P+  G      + +    +   E E  G    T+ +Y      +   
Sbjct: 1279 KESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGR 1338

Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
            +       T+    ++ L+  ++   R Y      +  ++E T    V     I+     
Sbjct: 1339 Q----TQYTERGRFLKILRVQATDAGR-YTCKAASVVGSTEKTFELDVYLPPTIKGDDAG 1393

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXX 1543
               + +    +  + L C  GG P P +TW +DG  ++ +++    E             
Sbjct: 1394 PTERKVVLSAS--LILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLS 1451

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEGI 1599
                Y C+A +  GE E    V +   P I     I++  +   H +  E   T    G 
Sbjct: 1452 DSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHPLEMECQAT----GT 1507

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P V WYK+G  ++  + + +    +  ++   ++  S ++++   A+N AG    + T
Sbjct: 1508 PTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQI--SDTARFQCVAANEAGDIQRDFT 1565

Query: 1660 LKVYDKPSKPE-GPVIMREI 1678
            + V++ PS P  G VI + I
Sbjct: 1566 VVVHEPPSVPHAGDVINQTI 1585



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 81/323 (25%), Positives = 124/323 (38%), Gaps = 22/323 (6%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           P  ++ P    V E   + L C L+A  P P   WL     +  D+ + V  +  +H   
Sbjct: 690 PVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWLHNYGLVTTDQYVKVRKDGSLH--- 746

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE--KEPPQVIEPLKSMIVRQGE 750
               I  V+    G YT +A N  G  +    L +      +  PQV   +      +G 
Sbjct: 747 ----IERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVIPTIQHGPQVFNTI------EGT 796

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
            V L  + +G P P ITW K  K +         D+     +      + G +   A N+
Sbjct: 797 PVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINSPSGNESGEFICMATNA 856

Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            G A     +TV      NAE P        ++V E     L   V   P P+ITW +  
Sbjct: 857 AGHASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDAILPCEVHSVPPPTITWAKER 916

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            +ISP           +++++ + V    DSG Y CVASN AG  +    V + V     
Sbjct: 917 -LISPFAPRHHPLPSCSMKILESKVS---DSGIYVCVASNIAGNLT--LSVLLSVLVPPS 970

Query: 931 VKHLQKSYETEEGKTVILECQTS 953
           ++   +  + + G  V L C  S
Sbjct: 971 IQPGPRVMKVQVGHPVELPCMVS 993



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 20/258 (7%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP  S K        GS  +L C +++    ++ WL  G +      ++V          
Sbjct: 376 PPAISVKGNVT-ASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNRS----- 429

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             L++++V   Q G Y  VA+N  G  S  I L   T ++EP   + P      R G+ V
Sbjct: 430 --LQLSSVSPDQSGWYECVAMNEGGVTSEQIYL---TVQEEPRVSVHPANQTFSR-GDEV 483

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +     G P P + W  N+  VKA      G    + I   ++ KD GVY   A N  G
Sbjct: 484 HMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIRNTEQ-KDGGVYRCLASNQAG 542

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
              T++V+T         E P+      ++ V       L    +  P P I WY+    
Sbjct: 543 TDATNSVLTY-------IESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAAPE 595

Query: 873 ISPSETITQNFDGENIEL 890
            +   + T +  G N+ L
Sbjct: 596 FTREPSDTASDIGSNVTL 613



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 63/284 (22%), Positives = 105/284 (36%), Gaps = 17/284 (5%)

Query: 632  IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            +PPT      +  V    G+ + LEC    +P P + W   G+ I+              
Sbjct: 1290 VPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGRF- 1348

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                 LKI  V+    G YT  A +  G       L +            P +  +V   
Sbjct: 1349 -----LKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERKVVLSA 1403

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             S+IL  +  G P P++TW K+  PV+   +    +      +    + D G Y   A +
Sbjct: 1404 -SLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLSDSGRYVCVATS 1462

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
              G  E    +TV  P        +        TV     +++  + T  P P +TWY++
Sbjct: 1463 VAGEKEVKYDVTVLVPPFIQGAGVI-----THSTVIINHPLEMECQATGTPTPVVTWYKD 1517

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             + I   E       G+ + +    +    D+  ++CVA+N AG
Sbjct: 1518 GKPIQQGEGWRVAAGGQRLLVSRAQIS---DTARFQCVAANEAG 1558



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 79/390 (20%), Positives = 147/390 (37%), Gaps = 33/390 (8%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKL 1360
            GS+VTL    + +P P   W     +    +  T  S+      L    +   D  +Y  
Sbjct: 608  GSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGLHFTHLWVEDEAVYVC 667

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN------TGNSTII- 1413
               N+ G  + +  +T+     P     ++    S +++  D+P         GN     
Sbjct: 668  EAHNHFGKIEAKARITVTGLVLP-----VIARSPSVLSVVEDQPVTLPCVLLAGNPLPAR 722

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             ++  Y  + T +++ V+        I+ ++ +    +   A N V + + + T   Y +
Sbjct: 723  QWLHNYGLVTTDQYVKVRK--DGSLHIERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVI 780

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--EN 1531
                    PT++   +   T     + L C   GVP P++TW ++GK L      +  ++
Sbjct: 781  --------PTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDS 832

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI-----SNEDIKQKHKV 1586
                            + C+A N  G       + +  +P         S E ++     
Sbjct: 833  DGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTE 892

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G++ ++   +  +PPP + W K   +L +            S+ +I E K S S  Y   
Sbjct: 893  GEDAILPCEVHSVPPPTITWAKE--RLISPFAPRHHPLPSCSM-KILESKVSDSGIYVCV 949

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
            ASN AG  ++ V L V   PS   GP +M+
Sbjct: 950  ASNIAGNLTLSVLLSVLVPPSIQPGPRVMK 979



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 14/206 (6%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            ++ ECQ  G P P +TW++     KP Q  + +        L++      D   F CVA 
Sbjct: 1498 LEMECQATGTPTPVVTWYKDG---KPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAA 1554

Query: 587  NAAG-FASSTTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            N AG      T ++ E P   H  ++   T+                  +PP  S +   
Sbjct: 1555 NEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPVISSQGGT 1614

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVK 701
              V       LEC    +P P   WL  G  +      + V  E         L + +  
Sbjct: 1615 VTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQVLSEG------RALSLNSAL 1668

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKI 727
                GTYT VAVN  GE      L++
Sbjct: 1669 VTDTGTYTCVAVNAGGEQQREYDLRV 1694



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 56/243 (23%), Positives = 91/243 (37%), Gaps = 16/243 (6%)

Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787
           K    EPP  I    ++    G   +L+  V+      +TW +  +  +  P  +  D  
Sbjct: 369 KISSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNR 428

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
           S+  L        G Y   A N  G+      +TV+E      EP + ++   + T    
Sbjct: 429 SLQ-LSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQE------EPRVSVHPANQ-TFSRG 480

Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
             + +    +  PVP + W  N+  +  S       DG    L I N + + D G Y+C+
Sbjct: 481 DEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDG---MLAIRNTEQK-DGGVYRCL 536

Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKK 965
           ASN AG  +  + +T     V  V           G+  +L C  S T   +  WY    
Sbjct: 537 ASNQAGTDATNSVLTYIESPVVTV--ALGDVLVALGEAAVLACAASGTPQPEIWWYKAAP 594

Query: 966 EIS 968
           E +
Sbjct: 595 EFT 597



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 48/212 (22%), Positives = 82/212 (38%), Gaps = 11/212 (5%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DG----KKLKTAKATYENRXXX 1535
            +P   +   +  ++   ++ L C+  G P P+VTW R DG     + +T  +  ++R   
Sbjct: 593  APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVT 1593
                        Y C A N  G++E    + +    V+ +          V D+   L  
Sbjct: 653  HFTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGL-VLPVIARSPSVLSVVEDQPVTLPC 711

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
             ++ G P P   W  N   +  D+   +    K   + I+ ++  H   YT  A N  G 
Sbjct: 712  VLLAGNPLPARQWLHNYGLVTTDQYVKV---RKDGSLHIERVRLDHVGDYTCLAENVVGL 768

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
             +   TL VY  P+   GP +   I    VT+
Sbjct: 769  YNHTTTLNVYVIPTIQHGPQVFNTIEGTPVTL 800



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 46/217 (21%), Positives = 82/217 (37%), Gaps = 11/217 (5%)

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
            RA +V+   I  A    ++ K+   +  + P       N+T  P     LTC        
Sbjct: 349  RASSVSFSSIKPAGVEGDWEKI---SSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSF 405

Query: 1512 KVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
             +TW R G+  +L       +NR               Y+C+A N+ G       + +Q+
Sbjct: 406  NLTWLRGGRDARLGPQVNVLDNR-SLQLSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQE 464

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
            +P +++      Q    GDE  +     G P P ++W  N   ++    + +       +
Sbjct: 465  EPRVSV--HPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRM---GPDGM 519

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            + I+  ++     Y   ASN AGT +    L   + P
Sbjct: 520  LAIRNTEQKDGGVYRCLASNQAGTDATNSVLTYIESP 556



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 7/180 (3%)

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXX 1534
            ++  P    PL+      N+ I   C   G+P+P + W R+G++L   +   +  E+   
Sbjct: 1011 EVLEPPFNSPLQERVA--NQRIAFPCPAKGLPKPVIRWLRNGQELTGNEPGVSILEDGTL 1068

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y C A ND G  E    + +   P  T +         +     +  
Sbjct: 1069 LLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSLVC 1128

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             + G P P + WYK    +       I    KT  +R+ +   + S  Y+ +A N AG++
Sbjct: 1129 DVTGSPSPVITWYKEEMPVVASDNVQILDMGKT--LRLLKADPADSGSYSCKAVNIAGSA 1186



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 3/130 (2%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXX 1538
            + P V     N T    +++ + C   G P P++ W  +   +K +++            
Sbjct: 464  EEPRVSVHPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIR 523

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                     Y+C+A N  G   T+ V+   + PV+T++  D+     +G+  ++     G
Sbjct: 524  NTEQKDGGVYRCLASNQAGTDATNSVLTYIESPVVTVALGDVLV--ALGEAAVLACAASG 581

Query: 1599 IPPPEVIWYK 1608
             P PE+ WYK
Sbjct: 582  TPQPEIWWYK 591



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 28/138 (20%), Positives = 54/138 (39%), Gaps = 4/138 (2%)

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGS 1303
            ++ +  R+L +   + D    Y CV ++    T  ++ + V+  P++  +       RG 
Sbjct: 422  VNVLDNRSLQLSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQEEPRVSVHPANQTFSRGD 481

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            +V +      +P P   W  N   +K     +   D     L I+  E  D G+Y+    
Sbjct: 482  EVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGM---LAIRNTEQKDGGVYRCLAS 538

Query: 1364 NNCGHADVEMNVTILDKP 1381
            N  G       +T ++ P
Sbjct: 539  NQAGTDATNSVLTYIESP 556



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 76/333 (22%), Positives = 123/333 (36%), Gaps = 32/333 (9%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
            EK  +L V+  PT +     P   E+   K     S +  EC+  G P P +TW +    
Sbjct: 1374 EKTFELDVYLPPTIKGDDAGP--TER---KVVLSASLI-LECEAGGRPPPSLTWLKDGVP 1427

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
            ++ SQ  ++    +    + I      D+G + CVA + AG      ++ V  P    G+
Sbjct: 1428 VRHSQSLRVL---ELGGKIEISSATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGA 1484

Query: 610  EMTVXXXXXXXXXXXXADILEGIPP---TFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
             +                   G P    T+ K  K     EG  +    + + +    I+
Sbjct: 1485 GVITHSTVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQIS 1544

Query: 667  WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726
               + + +  +E        D+    +V+    V +     +    +N+   A     L+
Sbjct: 1545 DTARFQCVAANE------AGDIQRDFTVV----VHEPPSVPHAGDVINQTILAGFSTQLE 1594

Query: 727  IK-TGEKEP-PQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---- 779
             K TG   P P VI      + V   E   L  +  G P P+ TW K+  PV ++P    
Sbjct: 1595 CKATGTPLPVPPVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQ 1654

Query: 780  TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
              S+G   S   L    V D G YT  A N+ G
Sbjct: 1655 VLSEGRALS---LNSALVTDTGTYTCVAVNAGG 1684



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 25/92 (27%), Positives = 37/92 (40%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP F  +     +  GS V   C V GYP PQ+TW RQ  +   ++         +   L
Sbjct: 593 APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
               ++ ED   + C A N  G   +   + V
Sbjct: 653 HFTHLWVEDEAVYVCEAHNHFGKIEAKARITV 684



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 1/77 (1%)

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
            +G+P P + W +NG +L  + E  ++  E  +++ +  +    S +Y   A+N AG++  
Sbjct: 1037 KGLPKPVIRWLRNGQELTGN-EPGVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTER 1095

Query: 1657 EVTLKVYDKPSKPEGPV 1673
            +  LKV   P   +  V
Sbjct: 1096 KYQLKVNVPPDFTDNEV 1112



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 4/125 (3%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX-XXXXXXXXXXX 1544
            +PL+   TE  ED  L C    VP P +TW ++      A   +                
Sbjct: 884  EPLRMSVTE-GEDAILPCEVHSVPPPTITWAKERLISPFAPRHHPLPSCSMKILESKVSD 942

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y C+A N  G +  S ++ +   P I      +K +  VG    +  ++ G+P P +
Sbjct: 943  SGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGPRVMKVQ--VGHPVELPCMVSGVPEPTL 1000

Query: 1605 IWYKN 1609
             W ++
Sbjct: 1001 TWTRD 1005


>UniRef50_UPI0000F1EA79 Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 512

 Score =  123 bits (296), Expect = 6e-26
 Identities = 100/413 (24%), Positives = 163/413 (39%), Gaps = 12/413 (2%)

Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADV 1719
            K   K   P   V   E  R  V + W  P+      +  Y IEK +     W +V   V
Sbjct: 68   KAEGKAPGPPSKVCASETDRTYVVLSWVSPVYHSKAPMWYY-IEKLQVGAGSWQRVNTKV 126

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXX 1778
                  Y +  L+E  +Y+FRV++ N  G SE  E    +    L  VPS          
Sbjct: 127  PIRSPRYAVFDLSEGKDYLFRVLSANIYGISEPSEPTSTITTLQLKGVPSAPGQVVATRE 186

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835
             D  SV I W P +      +I Y ++   +G K W           R  +  L+   +Y
Sbjct: 187  TDT-SVLIQWAPPKDPNN--LIGYYIDSCVKGSKDWASANHKPHKHTRFVVHGLTTGESY 243

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
             FR+ A NE+G S        +++   L  PS P +  +      S+ L W +P  +GG+
Sbjct: 244  VFRVQAINELGLSDESQESAPLSVRAALKLPSSPYDISLLYCDGESMVLNWKQPIHSGGA 303

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954
             +T+Y I+   V  K+W ++         H +  +       FR+   N VGV  P T S
Sbjct: 304  EVTDYYIDKCNVAKKTWKEVNIPPVKERLHKVGGLTAGSVYQFRVYGANVVGVGDPSTAS 363

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014
             S R +        P   L    V  + ++  W  P ++G + + GY I         W 
Sbjct: 364  PSFRCDAWTMSEPGPAYDLTFTEVRDDSLVVEWKPPVYNGASAVTGYFIEKCKKGSDSWS 423

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARN--EIGLSEPLESDEPFKVIPGE 2065
            +V +  V+     ++ L    +Y+ R+ A N  ++G++         + +P +
Sbjct: 424  KVNESSVDHCYLKVKGLETGTSYLFRVRAENAKDVGMASTPSDPVCVRALPAQ 476



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 19/187 (10%)

Query: 1301 RGSDVTLLVDYQAFPQPN-------DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
            R +D ++L+ +     PN       D  +  SK      H KP    K     +  +   
Sbjct: 185  RETDTSVLIQWAPPKDPNNLIGYYIDSCVKGSKDWASANH-KPH---KHTRFVVHGLTTG 240

Query: 1354 DAGIYKLRLENNCGHAD-----VEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
            ++ +++++  N  G +D       ++V   L  PS P   ++L  D  S+ + W +P ++
Sbjct: 241  ESYVFRVQAINELGLSDESQESAPLSVRAALKLPSSPYDISLLYCDGESMVLNWKQPIHS 300

Query: 1408 GNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            G + +  Y ++   +    W  +++  + +    +  L   S Y+FR Y  N V + D S
Sbjct: 301  GGAEVTDYYIDKCNVAKKTWKEVNIPPVKERLHKVGGLTAGSVYQFRVYGANVVGVGDPS 360

Query: 1466 ETTEYYK 1472
              +  ++
Sbjct: 361  TASPSFR 367



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 4/103 (3%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438
            PS PG+        +S+ I W  P++  N  +I Y ++     + +W S   K    T+ 
Sbjct: 175  PSAPGQVVATRETDTSVLIQWAPPKDPNN--LIGYYIDSCVKGSKDWASANHKPHKHTRF 232

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
             +  L T  SY FR  A+NE+ +SD S+ +    V    K+ S
Sbjct: 233  VVHGLTTGESYVFRVQAINELGLSDESQESAPLSVRAALKLPS 275



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITK 1435
            + +P P       E+   S+ + W  P   G S +  Y +E  +  +  W  V   ++  
Sbjct: 373  MSEPGPAYDLTFTEVRDDSLVVEWKPPVYNGASAVTGYFIEKCKKGSDSWSKVNESSVDH 432

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                ++ L+T +SY FR  A N  D+  AS  ++
Sbjct: 433  CYLKVKGLETGTSYLFRVRAENAKDVGMASTPSD 466



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 4/91 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P PP K    E D + + + W  P     + + YY +E  ++    W  V     I   +
Sbjct: 74   PGPPSKVCASETDRTYVVLSWVSPVYHSKAPMWYY-IEKLQVGAGSWQRVNTKVPIRSPR 132

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             ++ +L     Y FR  + N   IS+ SE T
Sbjct: 133  YAVFDLSEGKDYLFRVLSANIYGISEPSEPT 163


>UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin -
           Rattus norvegicus (Rat)
          Length = 603

 Score =  122 bits (294), Expect = 1e-25
 Identities = 102/367 (27%), Positives = 159/367 (43%), Gaps = 23/367 (6%)

Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
           Q L+ E  Y +  +  + E  D++   E P   E + AP F  KL+     +G  V F C
Sbjct: 243 QRLISEIEY-RLERSPVEESGDEVQEAEVPV--ENAAAPFFEMKLKHYKIFEGMPVTFTC 299

Query: 532 QVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
           +V G P+P+I WF+    I P  D + +  D D   +L       +D G +T +A N  G
Sbjct: 300 RVAGSPKPKIYWFKDGKQISPKSDHYTIQRDVDGTCSLHTTASTLDDDGNYTIMAANTQG 359

Query: 591 FASSTTELIVEA-------PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK 641
             S T  L+V+A       P S  G                  + ++     P F + P 
Sbjct: 360 RVSCTGRLMVQAVNQRGRSPRSPPGHPHARRPRSRSRDSGDENEPIQERFFRPHFLQAPG 419

Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNV 700
              V EG    ++C++  +P PD++W   G+ I PD    + + E+ +H     L I  V
Sbjct: 420 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHS----LIIEPV 475

Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVV 759
                G YT +A NR G+ S  + L +   E  + P  IE L++  V  G  V L  +V 
Sbjct: 476 TSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNTGVADGYPVRLECRVS 535

Query: 760 GNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
           G P P I W K N+ +      +    D   +   +++    +D G YT+ A+N  GI  
Sbjct: 536 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 595

Query: 816 TSAVITV 822
            +A + V
Sbjct: 596 CTARLDV 602



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 84/330 (25%), Positives = 140/330 (42%), Gaps = 45/330 (13%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F  K K   + EG  +   CR+   P+P I W   G++I P  +    I+ D+   CS
Sbjct: 278 PFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKIYWFKDGKQISPKSD-HYTIQRDVDGTCS 336

Query: 694 VLKITNVKKFQEGTYT-----------------VVAVNREGE----------ASLPIVLK 726
            L  T      +G YT                 V AVN+ G           A  P    
Sbjct: 337 -LHTTASTLDDDGNYTIMAANTQGRVSCTGRLMVQAVNQRGRSPRSPPGHPHARRPRSRS 395

Query: 727 IKTG-EKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL 778
             +G E EP       P  ++    + V++G+   +  +V G P P ++W  + KP++  
Sbjct: 396 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPD 455

Query: 779 PTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
                   +   HS+ I++P   +D G+YT  A N  G  + S  + +    +E  + P+
Sbjct: 456 SAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAG--QNSFNLELVVAAKEAHKAPV 512

Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIELVIT 893
           FI + Q   V +   ++L  RV+  P P I W + NE ++ S + ++ + D      ++ 
Sbjct: 513 FIEKLQNTGVADGYPVRLECRVSGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI 572

Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              ++ D+G Y   A N AG  S  AR+ +
Sbjct: 573 QGATKEDAGWYTVSAKNEAGIVSCTARLDV 602



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
           EP +E    P F+    ++TV+E    ++  +V+  P P ++W  + + I P        
Sbjct: 403 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLV 462

Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939
               +  +I    +  D+G Y C+A+N AG++S    + +  ++      F++ LQ +  
Sbjct: 463 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNT-G 521

Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972
             +G  V LEC+ S     + +  KKE   + H
Sbjct: 522 VADGYPVRLECRVSGVPPPQIFW-KKENESLTH 553



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 12/185 (6%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544
            ++T +  +   + C   G+P P ++W  DGK ++   A      EN              
Sbjct: 420  DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLIIEPVTSRD 479

Query: 1545 XXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIP 1600
               Y CIA N  G+       VV  ++     +  E + Q   V D + V     + G+P
Sbjct: 480  AGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKL-QNTGVADGYPVRLECRVSGVP 538

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            PP++ W K    L +  +     ++    I   I+   +  +  YT+ A N AG  S   
Sbjct: 539  PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 598

Query: 1659 TLKVY 1663
             L VY
Sbjct: 599  RLDVY 603



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 22/47 (46%), Positives = 32/47 (68%)

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
           + + TLVI E FPEDAG FTC A+N  G  +ST +L+V +  +++ S
Sbjct: 2   EEICTLVIAESFPEDAGIFTCSARNDYGSVTSTAQLVVTSANTENCS 48



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           + E+   +   E   ENA  P F  + +   + E   +    RV  +P P I W+++ + 
Sbjct: 258 VEESGDEVQEAEVPVENAAAPFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKIYWFKDGKQ 317

Query: 873 ISPSE---TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ISP     TI ++ DG  ++    + +D   D G+Y  +A+N+ G+ S   R+ +
Sbjct: 318 ISPKSDHYTIQRDVDGTCSLHTTASTLD---DDGNYTIMAANTQGRVSCTGRLMV 369



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 16/191 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F++   D  V+E  +  ++ +++   T D+ W+ DG+ I+P        +   +  L 
Sbjct: 412  PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLI 471

Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127
            I   +  D G Y+CI  +     S   E+ V        P  I +LQN  V  G     E
Sbjct: 472  IEPVTSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNTGVADGYPVRLE 531

Query: 1128 IELT-KGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180
              ++      + W K+   +  S + + +  D      L I     +DAG Y+     E 
Sbjct: 532  CRVSGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 591

Query: 1181 GNSKCTAILTV 1191
            G   CTA L V
Sbjct: 592  GIVSCTARLDV 602



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 1/76 (1%)

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            Y +    + ++ +  +  +V  E    +P  E  LK+        +  TC   G P+PK+
Sbjct: 251  YRLERSPVEESGDEVQEAEVPVENAA-APFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKI 309

Query: 1514 TWYRDGKKLKTAKATY 1529
             W++DGK++      Y
Sbjct: 310  YWFKDGKQISPKSDHY 325


>UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|Rep:
            Neogenin precursor - Homo sapiens (Human)
          Length = 1461

 Score =  122 bits (294), Expect = 1e-25
 Identities = 134/576 (23%), Positives = 226/576 (39%), Gaps = 37/576 (6%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            +D+ L C+  G+P P + W ++ + L T    +                     Y CIA 
Sbjct: 264  QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N +  +E    + +Q +P       +I     +  + +    + G P P V W KNG+ +
Sbjct: 324  NGNETIEAQAELTVQAQPEFLKQPTNIYAHESM--DIVFECEVTGKPTPTVKWVKNGDMV 381

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP- 1672
                 + I  +    V+    L +S    Y   A N  G +     L + +      GP 
Sbjct: 382  IPSDYFKIVKEHNLQVL---GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPL 438

Query: 1673 ------VIMREISRESVTIEWKPPLDD-GGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
                  V+   +S   + + W+ P  D  G  LT       E      ++      +++ 
Sbjct: 439  PSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQV 498

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP-SXXXXXXXXXXIDNESV 1784
              IQ L     Y+FRV+AQN  G  E+  S P+ ++T  +V                 S+
Sbjct: 499  -TIQNLMPATVYIFRVMAQNKHGSGES--SAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
             +TW  +  +G   I +YK+   ++G   +           I  L   T Y FR+ A N+
Sbjct: 556  TVTW-ETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNK 614

Query: 1845 IGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYI 1901
             G   P  S   + + +TL+  P + P+N  +    S+S+ + W  P  +     IT Y 
Sbjct: 615  HG---PGVSTPDVAV-RTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYK 670

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            I ++    KS      V G+     IE +    E  FR++A    G    T+  S    +
Sbjct: 671  IRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFE 730

Query: 1962 ----HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
                   VP  P++ L +R + ++IV+ SW  PE +    + GY  AI     +   +  
Sbjct: 731  SDLDETRVPEVPSS-LHVRPLVTSIVV-SWTPPE-NQNIVVRGY--AIGYGIGSPHAQTI 785

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
            KVD     + I +L  +  Y+I + A N +G   PL
Sbjct: 786  KVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPL 821



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 208/1008 (20%), Positives = 359/1008 (35%), Gaps = 106/1008 (10%)

Query: 1035 ILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNT--SVH---DEGEYS 1088
            IL     SE +  + W++DG  +    +  D  +      L+I N   S H   DEG Y 
Sbjct: 71   ILNCSAYSEPSPKIEWKKDGTFLNLVSD--DRRQLLPDGSLFISNVVHSKHNKPDEGYYQ 128

Query: 1089 CILRDESC------TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFK 1141
            C+   ES       TA++ V  LP    ++ +   V  GN A    E+       VRW +
Sbjct: 129  CVATVESLGTIISRTAKLIVAGLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQ 187

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPS 1195
            +   +   + +     G    L I +    D G Y C V +      S    +  + +P 
Sbjct: 188  NRQPLLLDDRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPE 244

Query: 1196 INFTL---RLPEFILVPANTDAYLT-VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            +   L   + P  ++     D  L  V     T  + W K +  + DTE    +  +   
Sbjct: 245  VISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL-DTESSERLVLLAGG 303

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            +L I   TEDD   Y C+  +   T + + E+ V+  P+ +            D+    +
Sbjct: 304  SLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECE 363

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
                P P  +W+ N  ++    + K     K  +L +  +  +D G Y+   EN+ G+A 
Sbjct: 364  VTGKPTPTVKWVKNGDMVIPSDYFKIV---KEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420

Query: 1371 VEMNVTILDK--------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
                + IL+         PS P       + +  I + W  P +  +   + Y V Y   
Sbjct: 421  AGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFY--- 477

Query: 1423 DTTEWISVKNITKT------QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
             T E I+ + +  T      Q +IQNL   + Y FR  A N+     + E++   +V  +
Sbjct: 478  -TKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNK---HGSGESSAPLRVETQ 533

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX 1534
             ++Q P     L+     P        T + G         Y   K     +    +   
Sbjct: 534  PEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHS 593

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGE-VETS--CVVGIQQKPVITISN--EDIKQKHKVGDE 1589
                         ++ +A+N HG  V T    V  +   P     N   +++    +   
Sbjct: 594  YTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIH 653

Query: 1590 WL--VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
            W     A   G      I Y+  ++  +  E  ++  + + +  I+ L R     + + A
Sbjct: 654  WQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQL--IEGLDRGTEYNFRVAA 711

Query: 1648 SNTAGTS------SVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGGLELTK 1700
                GT       S E      D+   PE P  +       S+ + W PP ++  + +  
Sbjct: 712  LTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPP-ENQNIVVRG 770

Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG----FSEALESE 1756
            YAI       +   +   VD     Y I+ L+ +  Y+  + A N VG      E+  + 
Sbjct: 771  YAI--GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTR 828

Query: 1757 PIVIKTALDV--------------PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID- 1801
            P    + +D+              P           + ++++ ITW  +       I D 
Sbjct: 829  PHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDS 888

Query: 1802 --YKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
              Y V  K       K+K           +  L  NT Y+F +       +S    +   
Sbjct: 889  RYYTVRWKTNIPANTKYKNANATTLSYL-VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHG 947

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT---VKGKSWT 1913
             T     T P +    V  E   +++ + W +P S     IT YII + T    +   W 
Sbjct: 948  TTFELVPTSPPKDVTVVSKEGKPKTIIVNW-QPPSEANGKITGYIIYYSTDVNAEIHDWV 1006

Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
             I  V G+   H I+ +       F+I A N+ G+   +E+   R  K
Sbjct: 1007 -IEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPK 1053



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 102/468 (21%), Positives = 183/468 (39%), Gaps = 28/468 (5%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            +G + ++  V  G+P P + W KN   L+ +    +      S + I ++    +  Y  
Sbjct: 262  IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFC 320

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
             A N   T   +  L V  +P   + P  +   + ES+ I ++  +        K+    
Sbjct: 321  IADNGNETIEAQAELTVQAQPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKWV--- 375

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLN--ENCEYMFRVIAQNPVGFSEALESEPIVIK-- 1761
                N   +  +D  + V+ + +Q L   ++ E  ++ IA+N VG ++A  ++ I+++  
Sbjct: 376  ---KNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQA-GAQLIILEHA 431

Query: 1762 --TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG---KKWKXX 1816
              T   +PS          +    + +TW     +     + Y V   +EG   ++ +  
Sbjct: 432  PATTGPLPSAPRDVVASL-VSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENT 490

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     IQ L   T Y FR+ A+N+ G+    ++  ++     +  P    N     
Sbjct: 491  SHPGEMQVTIQNLMPATVYIFRVMAQNKHGSG-ESSAPLRVETQPEVQLPGPAPNLRAYA 549

Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936
            ++  S+T+ W  P S  G  I NY + +   KG    + V V  S H + I  +K+  E 
Sbjct: 550  ASPTSITVTWETPVSGNGE-IQNYKLYYME-KGTDKEQDVDV--SSHSYTINGLKKYTEY 605

Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP-EWDGG 1995
             FR+ A N  G  + T   +VR        +P    LE+R   S  +M  W  P      
Sbjct: 606  SFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVR--NSKSIMIHWQPPAPATQN 663

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
              + GY I  R  ++   +    V    L   I  L     Y  R+ A
Sbjct: 664  GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAA 711



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 85/306 (27%), Positives = 137/306 (44%), Gaps = 35/306 (11%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
           I+ G+P  F+ +P+   V  G++ +L C + A   P + W    + ++ D+ + + + S 
Sbjct: 147 IVAGLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRV-IKLPSG 204

Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-----K 742
           M      L I+N  +   G Y  V V   G       +++K      P+VI  L      
Sbjct: 205 M------LVISNATEGDGGLYRCV-VESGGPPKYSDEVELKV--LPDPEVISDLVFLKQP 255

Query: 743 SMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVK- 798
           S +VR  G+ V+L     G P PTI W KN +   AL T+S      +    L+   V  
Sbjct: 256 SPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE---ALDTESSERLVLLAGGSLEISDVTE 312

Query: 799 -DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            D G Y   A+N     E  A +TV+      A+P  F+ +   I   E   I     VT
Sbjct: 313 DDAGTYFCIADNGNETIEAQAELTVQ------AQPE-FLKQPTNIYAHESMDIVFECEVT 365

Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
             P P++ W +N +++ PS+   +     N++ V+  V S  D G Y+C+A N  G +  
Sbjct: 366 GKPTPTVKWVKNGDMVIPSDYF-KIVKEHNLQ-VLGLVKS--DEGFYQCIAENDVGNAQA 421

Query: 918 GARVTI 923
           GA++ I
Sbjct: 422 GAQLII 427



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 91/384 (23%), Positives = 157/384 (40%), Gaps = 40/384 (10%)

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITI 791
            ++EP+ ++ VR G SVIL+      P P I W K+   +  +         DG      +
Sbjct: 56   LVEPVDTLSVR-GSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114

Query: 792  LKPKKVK-DEGVYTLKA--ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            +  K  K DEG Y   A  E+   I   +A + V       A  P F ++ +  +V    
Sbjct: 115  VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIV-------AGLPRFTSQPEPSSVYAGN 167

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
               L   V  + VP + W +N + +   + + +   G    LVI+N  +E D G Y+CV 
Sbjct: 168  NAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSG---MLVISNA-TEGDGGLYRCVV 223

Query: 909  SNSAGKSSHGARVTI----DVEKVTFVKHLQKSYETEE--GKTVILECQTS--HTVSTKW 960
              S G   +   V +    D E ++ +  L++        G+ V+L C  S   T + KW
Sbjct: 224  -ESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKW 282

Query: 961  YHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--- 1016
              N++ + +    R ++  G             D G   CI  +   +     + T+   
Sbjct: 283  MKNEEALDTESSERLVLLAG--GSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            PEF+++  +    E    + E E+  + T  V W ++G+++ P     D+ K      L 
Sbjct: 341  PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS----DYFKIVKEHNLQ 396

Query: 1076 IRNTSVHDEGEYSCILRDESCTAE 1099
            +      DEG Y CI  ++   A+
Sbjct: 397  VLGLVKSDEGFYQCIAENDVGNAQ 420



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 52/197 (26%), Positives = 87/197 (44%), Gaps = 10/197 (5%)

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           F K+P       G D++L C    +P P I W+ K EE +  E+     E  + +    L
Sbjct: 251 FLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWM-KNEEALDTESS----ERLVLLAGGSL 305

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
           +I++V +   GTY  +A N  G  ++    ++ T + +P  + +P  ++   +   ++  
Sbjct: 306 EISDVTEDDAGTYFCIADN--GNETIEAQAEL-TVQAQPEFLKQPT-NIYAHESMDIVFE 361

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            +V G P PT+ W KN   V           H++ +L   K  DEG Y   AEN  G A+
Sbjct: 362 CEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVK-SDEGFYQCIAENDVGNAQ 420

Query: 816 TSAVITVEEPTEENAEP 832
             A + + E       P
Sbjct: 421 AGAQLIILEHAPATTGP 437



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 87/402 (21%), Positives = 151/402 (37%), Gaps = 24/402 (5%)

Query: 626  ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVA 683
            A I    P  F  +P       GS ++L C   + P P I W   G    +V D+   + 
Sbjct: 45   ASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLL 104

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
               D  ++ S +  +   K  EG Y  VA        +    K+       P+     + 
Sbjct: 105  --PDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL--PRFTSQPEP 160

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
              V  G + IL+ +V  +  P + W +N +P+  L  +       + ++      D G+Y
Sbjct: 161  SSVYAGNNAILNCEVNADLVPFVRWEQNRQPL-LLDDRVIKLPSGMLVISNATEGDGGLY 219

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
                E+      +  V     P  E     +F+ +   +       + L    +  P P+
Sbjct: 220  RCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPT 279

Query: 864  ITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            I W +N E +    SE +     G    L I++V +E D+G Y C+A N        A +
Sbjct: 280  IKWMKNEEALDTESSERLVLLAGG---SLEISDV-TEDDAGTYFCIADNGNETIEAQAEL 335

Query: 922  TIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979
            T+  +   F+K     Y   E   ++ EC+ +   T + KW  N   +   D+ +I++E 
Sbjct: 336  TVQAQP-EFLKQPTNIY-AHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKE- 392

Query: 980  RXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIP 1017
                         D G  +CI    V + +    L++ E  P
Sbjct: 393  --HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAP 432



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 4/91 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++    +  +   + FEC+V G P P + W +   ++ PS  F++  + +    L 
Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN----LQ 396

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           +  +   D G + C+A+N  G A +  +LI+
Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLII 427



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)

Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570
           +F+++  P     G  V   C   G P P I W +    +      ++        +L I
Sbjct: 250 VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG--SLEI 307

Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            +V  +DAGT+ C+A N      +  EL V+A
Sbjct: 308 SDVTEDDAGTYFCIADNGNETIEAQAELTVQA 339


>UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n=3;
            Danio rerio|Rep: UPI00015A60B9 UniRef100 entry - Danio
            rerio
          Length = 3050

 Score =  121 bits (291), Expect = 3e-25
 Identities = 154/716 (21%), Positives = 267/716 (37%), Gaps = 76/716 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+  + D  V E     + V +  +   ++ W RD   IK        E      ++ 
Sbjct: 671  PAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMI 730

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE----IITRLQNQKVNKGNKATFE 1127
            I++    D G Y+C + +E     C  ++ V   P E    II  +++  V  G  A FE
Sbjct: 731  IKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETALFE 790

Query: 1128 IELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC------- 1178
              +    D  V W  DG  IQ +  + ++  DGK+ +L +     DD+G Y+C       
Sbjct: 791  CHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKE 850

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238
            E+ +S    ++   EP   FT +L    ++      +           V W      +E+
Sbjct: 851  ELTSSAKLKVIASIEPL--FTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEE 908

Query: 1239 TEKFTLISDVKKRTLII---------------RKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
             E   ++ +  + +LII               R    +D+C     + + +     ++  
Sbjct: 909  NEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAK 968

Query: 1284 VEFPPKIVDYER--EYRIKR-----------------GSDVTLLVDYQAFPQPNDEWIVN 1324
            +E  P I +     E  I+R                 G +  L       P P   W  N
Sbjct: 969  LEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHN 1028

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSP 1383
             K I   +  K +      SL ++ V +   G+YK  + N  G A    ++ + D  P P
Sbjct: 1029 GKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDP 1088

Query: 1384 P-GKPNILEIDSSSINICWDEPENTGNS---TIIYYVVEYQEIDTTEWISVKNITKTQT- 1438
            P G P +  I   +I + W +P+    S   + + Y ++ Q + + +W  + +  K  T 
Sbjct: 1089 PDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTY 1148

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPN 1496
            +I NL     Y FR  ++     S  S  TE  +++       ++P +      +     
Sbjct: 1149 TISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEK 1208

Query: 1497 EDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE------NRXXXXXXXXXXXXXXXYK 1549
            + + +T     V    VTW R  G  L      +E      ++                 
Sbjct: 1209 QPLSITVTLNHV-NASVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLT 1267

Query: 1550 CIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            CIA N +G    SCV+ ++    P      ED+     VG+      V+EG P P+++WY
Sbjct: 1268 CIANNKYGS--DSCVLTLEMAVAPTFETIMEDLDVN--VGETPRFAVVVEGKPVPDILWY 1323

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            K    L     +     +    + +   +   S  YT  A N AG+ S +  L V+
Sbjct: 1324 KGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVH 1379



 Score =  109 bits (263), Expect = 6e-22
 Identities = 102/452 (22%), Positives = 183/452 (40%), Gaps = 29/452 (6%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           E+   AP+F   L+      G+ V  +C + G P P++ W +    +K S    +  + +
Sbjct: 527 EDPLEAPVFEFPLQDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGE 586

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APLSDHGSEMTVXXXXXXXX 621
              +L+I+   P DAGT+T  A N  G  SS+  L ++  A  S + S +T         
Sbjct: 587 R-HSLLIKWTKPSDAGTYTVTAVNEVGEVSSSATLFIKPGACKSKYSSPITSDEEYLSPL 645

Query: 622 XXXX-------------ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668
                             D     PP F      Q V EG ++ +   +   P+P + WL
Sbjct: 646 EESMDFSSYRGPEPRKIVDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWL 705

Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
            +    +      +  E++   +  ++K  + ++   G YT   +N  G       L++K
Sbjct: 706 -RDRVTIKTGTRHIVQETEEGNFEMIIK--SAQRSDTGVYTCKIINEYGTKQCEGKLEVK 762

Query: 729 TGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGD 785
               EP   +I P++ ++V+ GE+ +    V+G     + W  + K ++   L  K   D
Sbjct: 763 ARPVEPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFD 822

Query: 786 THSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
                +L     +D+ G YT K   ++    +SA + V    E     PLF  +   + V
Sbjct: 823 GKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIE-----PLFTRKLDVLEV 877

Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
            E    +   +V+  P P + W   +  +  +E I    +G    L+I++V +E D G Y
Sbjct: 878 IEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNE-DEGLY 936

Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
              A NS G+    A + +   +      + K
Sbjct: 937 TVAARNSHGEDECAAELYVQEPRPAISSQIAK 968



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 109/475 (22%), Positives = 178/475 (37%), Gaps = 67/475 (14%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            +  +  Y   L++ ++    + P   K         P F+  +  +   +G  V     V
Sbjct: 635  ITSDEEYLSPLEESMDFSSYRGPEPRKIVDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLV 694

Query: 534  EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593
             G P+P + W R    IK      +   ++    ++I+     D G +TC   N  G   
Sbjct: 695  TGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVYTCKIINEYGTKQ 754

Query: 594  STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653
               +L V+A   + G                    L  I P      KA     G   L 
Sbjct: 755  CEGKLEVKARPVEPG--------------------LAIIRPVRDVMVKA-----GETALF 789

Query: 654  ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVKKFQEGTYTV 710
            EC ++   + D+ WL  G+ I P       +   MH     C +L + +V +   GTYT 
Sbjct: 790  ECHVIGPQDTDVDWLSDGKLIQP-----ALLNCKMHFDGKRCRLL-LNSVHEDDSGTYTC 843

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
                 + E  L    K+K      P     L  + V +G +     +V G P P + W  
Sbjct: 844  KLSTAKEE--LTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSH 901

Query: 771  NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP-- 825
             ++P++    +    +G  HS+ I+     +DEG+YT+ A NS G  E +A + V+EP  
Sbjct: 902  FDRPLEENEDIRILKEGGRHSL-IISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRP 960

Query: 826  ---------------TEENAEP---------PLFINRFQEITVKEKGTIKLVARVTRNPV 861
                            EE   P         P F+    ++ V E     L  +V   P 
Sbjct: 961  AISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPY 1020

Query: 862  PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            P+ITW+ N + I  +E   +     ++  ++         G YKCV SN  GK++
Sbjct: 1021 PTITWFHNGKRIDSTED-RKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKAT 1074



 Score = 87.4 bits (207), Expect = 4e-15
 Identities = 112/529 (21%), Positives = 202/529 (38%), Gaps = 32/529 (6%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            S+ P+F  KL      +G   +F+C+V G P PQ+ W      ++ ++D ++  +     
Sbjct: 863  SIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGR-H 921

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623
            +L+I  V  ED G +T  A+N+ G      EL V+ P   +S   +++            
Sbjct: 922  SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEV 981

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
               +I     P F K      V EG + +L C++  +P P I W   G+ I   E+  + 
Sbjct: 982  PENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMT 1041

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
               D+H     L +  V     G Y  V  N+ G+A+    L +     +PP     ++S
Sbjct: 1042 QFRDVHS----LVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDPPDGAPVVES 1097

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK----D 799
            +    G+++ LS +      P+I        ++     S   T   + LK          
Sbjct: 1098 I---TGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLS 1154

Query: 800  EGV---YTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGTIKLV 853
            +GV   + + +  S+  ++ S      +  +      E P+ I++   + + EK  + + 
Sbjct: 1155 KGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEKQPLSIT 1214

Query: 854  ARVTRNPV-PSITWYRNNEII---SPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
              VT N V  S+TW R   +     P        D +   L +  V S  D G   C+A+
Sbjct: 1215 --VTLNHVNASVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSS-DVGQLTCIAN 1271

Query: 910  NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEI 967
            N  G  S    +T+++      + + +  +   G+T    +  +        WY     +
Sbjct: 1272 NKYGSDS--CVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLL 1329

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
            S   H   + +              D GV  C  K+   S     + T+
Sbjct: 1330 SESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1378



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 71/312 (22%), Positives = 123/312 (39%), Gaps = 15/312 (4%)

Query: 727  IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786
            + T  KEPP  +  +    V +G+ V +S  V G P+P + W ++   +K        +T
Sbjct: 663  VDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQET 722

Query: 787  HS---ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR-FQEI 842
                   I+K  +  D GVYT K  N  G  +    + V+       EP L I R  +++
Sbjct: 723  EEGNFEMIIKSAQRSDTGVYTCKIINEYGTKQCEGKLEVK---ARPVEPGLAIIRPVRDV 779

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDS 901
             VK   T      V       + W  + ++I P+      +FDG+   L++ +V  E DS
Sbjct: 780  MVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSV-HEDDS 838

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-- 959
            G Y C  S +  + +  A++ +               E  EG+    +C+ S T   +  
Sbjct: 839  GTYTCKLSTAKEELTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVI 898

Query: 960  WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTMLVVKET 1015
            W H  + +   +   I++EG             D G+     +    + E +  L V+E 
Sbjct: 899  WSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP 958

Query: 1016 IPEFIRKLQDFE 1027
             P    ++   E
Sbjct: 959  RPAISSQIAKLE 970



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 41/169 (24%), Positives = 83/169 (49%), Gaps = 5/169 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E ++   + G+P P + W+ NG ++++ ++  +T       + ++ +  +H   Y   
Sbjct: 1006 GREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCV 1065

Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702
             SN  G ++    L V D  P  P+G  ++  I+ +++T+ WK P   D  ++ +   YA
Sbjct: 1066 ISNKVGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYA 1125

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            I++    + +W  +A   +   TY I  L++   Y FRV++     FS+
Sbjct: 1126 IQQQALGSIQWTIIASCLKQT-TYTISNLSKGVRYAFRVLSITSKAFSK 1173



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 1/101 (0%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E ++AP F   +       G T +F   VEG P P I W++   ++  S  F   Y DDN
Sbjct: 1284 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVY-DDN 1342

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
              +LV+     +D+G +TC AKN AG  S   EL V   ++
Sbjct: 1343 ECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVHTNIT 1383



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 76/320 (23%), Positives = 131/320 (40%), Gaps = 24/320 (7%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF-SNHI-QLTIDGKKQK 1162
            PP  +  + +Q V +G + T  + +T +   ++ W +D   I+  + HI Q T +G  + 
Sbjct: 670  PPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEM 729

Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVE----EPSINFTLRLPEFILVPANTDA 1214
            + I      D G Y+C++    G  +C   L V+    EP +   +R    ++V A   A
Sbjct: 730  I-IKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAI-IRPVRDVMVKAGETA 787

Query: 1215 YLTVEI--PDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
                 +  P +T DV W     +I+       +  D K+  L++    EDD   YTC L 
Sbjct: 788  LFECHVIGPQDT-DVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLS 846

Query: 1272 DAK----STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
             AK    S+ KLKV +    P          +  G +          P P   W    + 
Sbjct: 847  TAKEELTSSAKLKV-IASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRP 905

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +++ +  +   +    SL I  V N D G+Y +   N+ G  +    + +  +P P    
Sbjct: 906  LEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYV-QEPRPAISS 964

Query: 1388 NILEIDS-SSINICWDEPEN 1406
             I +++   SI    + PEN
Sbjct: 965  QIAKLEKMPSIPEEPEVPEN 984



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 8/215 (3%)

Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKS 1342
            ++FPP      R++ +  G  VTL       P P+  W+ + K ++   +    S     
Sbjct: 2371 IDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGR 2430

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L I K    DAG+Y+    N          V++   P+ PG P + +   ++  + W 
Sbjct: 2431 QLLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVVWR 2490

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              + T   T   Y +E +      W+ V   +     ++ +L   +SYRFR   VN+   
Sbjct: 2491 PSDTTAPCT---YSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQ 2547

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               S  +E   V+ ++ ++ P   KP  +  + P+
Sbjct: 2548 GPYSSLSEV--VVLDSTVK-PAAIKPAPSTNSAPS 2579



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 40/121 (33%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 491  KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
            K++K+P      E P +E E+   P FV+ L      +G      C+V G P P ITWF 
Sbjct: 968  KLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFH 1027

Query: 546  QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
                I  ++D +M    D V +LV+R V     G + CV  N  G A+  + L V   L 
Sbjct: 1028 NGKRIDSTEDRKMTQFRD-VHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILP 1086

Query: 606  D 606
            D
Sbjct: 1087 D 1087



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTI 1645
            GD   ++ +  G P P + W K+   LE D   N I+  +   ++ I +  +  +  Y  
Sbjct: 2389 GDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYEC 2448

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
             A+N   T +    + +   P+ P  P + ++    ++ + W+P   D     T Y++E+
Sbjct: 2449 VAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVV-WRP--SDTTAPCT-YSLER 2504

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                 N W+ VA    D   Y +  L     Y FRV   N  G
Sbjct: 2505 KTEGENNWLIVATGVADC-YYNVLDLPAGASYRFRVACVNKAG 2546



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 25/74 (33%), Positives = 38/74 (51%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E L+  +I G P PEVIW K+  +++N   + +  + +   + IK  K S +  YT+ 
Sbjct: 547  GTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSDAGTYTVT 606

Query: 1647 ASNTAGTSSVEVTL 1660
            A N  G  S   TL
Sbjct: 607  AVNEVGEVSSSATL 620



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 65/320 (20%), Positives = 119/320 (37%), Gaps = 28/320 (8%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK-CKHTKPSIDSKSASL 1345
            PP  +    +  +  G +VT+ V     P+P   W+ +   IK   +H     +  +  +
Sbjct: 670  PPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEM 729

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
             IK  + +D G+Y  ++ N  G    E  + +  +P  PG   I  +         D   
Sbjct: 730  IIKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVR--------DVMV 781

Query: 1406 NTGNSTII-YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
              G + +   +V+  Q+ D  +W+S   +   Q ++ N K +   +     +N V   D+
Sbjct: 782  KAGETALFECHVIGPQDTD-VDWLSDGKL--IQPALLNCKMHFDGKRCRLLLNSVHEDDS 838

Query: 1465 SETTEYYKVIKETKIQSPTVE-----KPLKNITTEPNEDIE-----LTCIFGGVPQPKVT 1514
               T      KE    S  ++     +PL     +  E IE       C   G P P+V 
Sbjct: 839  GTYTCKLSTAKEELTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVI 898

Query: 1515 WYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ- 1569
            W    + L+  +         R               Y   A N HGE E +  + +Q+ 
Sbjct: 899  WSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP 958

Query: 1570 KPVITISNEDIKQKHKVGDE 1589
            +P I+     +++   + +E
Sbjct: 959  RPAISSQIAKLEKMPSIPEE 978



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 26/95 (27%), Positives = 41/95 (43%)

Query: 501  PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            P +++    P+F  KLR     +G  V   C   G P P I+W +    ++      M  
Sbjct: 2366 PFNQKIDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMIS 2425

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
              D    L+I +   +DAG + CVA N     +S+
Sbjct: 2426 CPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSS 2460



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 47/203 (23%), Positives = 75/203 (36%), Gaps = 10/203 (4%)

Query: 1375 VTILDKP--SPPGKPNILEIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDT-TEWIS 1429
            V I D P  +PP  P +    SS   + +    P      TI   +VE + ++T T    
Sbjct: 422  VAIQDFPVQAPPKPPRVSSSSSSEEKMELEVTPPPPPLKLTIPKIIVEEEPMETDTPVEK 481

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
             +   K  T        S  R R       +++  S    Y     E  +++P  E PL+
Sbjct: 482  TEKAVKVGTGKDEKHQRSRGRGRRQRPMSPELATESSDDSYVSA-GEDPLEAPVFEFPLQ 540

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXX 1545
            +       ++ L CI  G P P+V W +D  ++K +          R             
Sbjct: 541  DTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSDA 600

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQ 1568
              Y   A N+ GEV +S  + I+
Sbjct: 601  GTYTVTAVNEVGEVSSSATLFIK 623



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
            PP     L+  ++ +G+ V LS    G+P P I+W K+ KP++  P     S  D   + 
Sbjct: 2374 PPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLL 2433

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++     KD G+Y   A N      +S V+++
Sbjct: 2434 MIMKTTKKDAGLYECVAANPLATVTSSCVVSL 2465



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 9/118 (7%)

Query: 993  DVGVIKCIVKDQ--ETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETA-DVV 1048
            DVG + CI  ++    S +L ++  + P F   ++D +V   +     V +  +   D++
Sbjct: 1262 DVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDIL 1321

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102
            W + G+ +  + + + F    +   L + NT   D G Y+C  ++     SC AE+TV
Sbjct: 1322 WYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1378



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 8/136 (5%)

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            V++ DI  AS   E   +    KI  P V    L++      + + L+C+  G P P ++
Sbjct: 2349 VSQPDIP-ASIARENGSLPFNQKIDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHIS 2407

Query: 1515 WYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            W +D K L+        +  + R               Y+C+A N    V +SCVV + +
Sbjct: 2408 WMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLAR 2467

Query: 1570 KPVITISNEDIKQKHK 1585
             P  +    ++ QK+K
Sbjct: 2468 LP-NSPGTPEVPQKYK 2482



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTI 1645
            G E  ++ ++ G P P + W ++   ++    + +  T+E    + IK  +RS +  YT 
Sbjct: 685  GQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVYTC 744

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
            +  N  GT   E  L+V  +P +P G  I+R +
Sbjct: 745  KIINEYGTKQCEGKLEVKARPVEP-GLAIIRPV 776



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 38/186 (20%), Positives = 68/186 (36%), Gaps = 9/186 (4%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYEN-RXXXXXXXX 1540
            +P++++  +  E     C   G     V W  DGK ++ A    K  ++  R        
Sbjct: 774  RPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSV 833

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGI--QQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                   Y C       E+ +S  + +    +P+ T    D+ +  + G        + G
Sbjct: 834  HEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPLFT-RKLDVLEVIE-GRNARFDCKVSG 891

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
             PPP+VIW      LE +++  I  +     + I  +       YT+ A N+ G      
Sbjct: 892  TPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAA 951

Query: 1659 TLKVYD 1664
             L V +
Sbjct: 952  ELYVQE 957


>UniRef50_Q17AE8 Cluster: Titin; n=3; Culicidae|Rep: Titin - Aedes
           aegypti (Yellowfever mosquito)
          Length = 1393

 Score =  120 bits (290), Expect = 3e-25
 Identities = 116/433 (26%), Positives = 184/433 (42%), Gaps = 57/433 (13%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  ++ E +V G P P++ W         +++F  +Y++   A LVI E F +DAG +T 
Sbjct: 21  GQKIKLEAEVAGTPPPEVMWSHDGMHFS-NREF--FYENGR-AQLVIDEAFLKDAGVYTL 76

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            AKN AG  S +  ++V+  L +  S+  +            A  +E + P+   + K  
Sbjct: 77  TAKNIAGEKSCSCNVVVKGRLPNETSDSEL------------ASDMEPVKPSVQLQLKDV 124

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V EG  + L+C +V  PEP++ W      +    +  +  + D   +CS L I      
Sbjct: 125 SVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGD---HCS-LVIREAFLE 180

Query: 704 QEGTYTVVAVNREGEASLP---IVLKIKTGE---KEPPQVIEP-----------LKSMIV 746
             G Y VVA+N  GEAS     IV  +   E   ++P + I P           L  ++ 
Sbjct: 181 DAGEYRVVAINSAGEASSKCSVIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDILA 240

Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPT-----KSDGDTHSITILKPKKVKDEG 801
            +GE       V G+PRP I W  NN+ +   P      + DG      I++     D+G
Sbjct: 241 AEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHSVYRDDGVVK--LIIEQVFPDDKG 298

Query: 802 VYTLKAENSEGIAE--TSAVITVEEPTEENAEP---------PLFINRFQEITVKEKGTI 850
           VYT KA N  G A+  ++ ++      E  + P         P F   F +  VK   + 
Sbjct: 299 VYTAKAFNPSGEAKCFSNLIVKSINAAEFESVPAFLSDSVVCPTFKELFADRVVKLHEST 358

Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
           K    V   P P I W+ N++ +   + +     G+   L I  V  E+ +G   C A N
Sbjct: 359 KFECIVVGKPQPKIKWFFNDQPVQGHDFLVST-SGDRQVLTIPEVSPEL-AGKITCFAEN 416

Query: 911 SAGKSSHGARVTI 923
            AG +   A V +
Sbjct: 417 EAGNAQCVAYVRL 429



 Score =  112 bits (270), Expect = 9e-23
 Identities = 100/338 (29%), Positives = 143/338 (42%), Gaps = 30/338 (8%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+ + + P    +L+     +G  V+ +C + G P P++ W+     +K S DFQ+ +  
Sbjct: 108 SDMEPVKPSVQLQLKDVSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQG 167

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
           D+  +LVIRE F EDAG +  VA N+AG ASS   +IV  PL+   +E  V         
Sbjct: 168 DH-CSLVIREAFLEDAGEYRVVAINSAGEASSKCSVIV-TPLNI--AEPAVRQPAERILP 223

Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                   G PP F +        EG     EC +   P P+I W     EIV +  +  
Sbjct: 224 AL------GAPPKFERLLSDILAAEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHS 277

Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGEKEP----- 734
               D  +    L I  V    +G YT  A N  GEA   S  IV  I   E E      
Sbjct: 278 VYRDDGVV---KLIIEQVFPDDKGVYTAKAFNPSGEAKCFSNLIVKSINAAEFESVPAFL 334

Query: 735 ------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDT 786
                 P   E     +V+  ES      VVG P+P I W  N++PV+       + GD 
Sbjct: 335 SDSVVCPTFKELFADRVVKLHESTKFECIVVGKPQPKIKWFFNDQPVQGHDFLVSTSGDR 394

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             +TI +    +  G  T  AEN  G A+  A + + +
Sbjct: 395 QVLTIPEVSP-ELAGKITCFAENEAGNAQCVAYVRLAD 431



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 11/205 (5%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F      + VD+G+D+  E  +   P P++       E+ PD    +A+   ++    
Sbjct: 568 PRFVSPFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGE-RIAVSYSLNKI-- 624

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
           V+++ NV     G YT  A N  G +S    L +K     PP     L++  V +GE +I
Sbjct: 625 VVELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIF-PPVFGRRLQAQSVHRGERII 683

Query: 754 LSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           L A+V G P PT+ W K+N+PV+      +   +  G T  + I +     D G + + A
Sbjct: 684 LDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKL-IFEQIDFADAGKFMIVA 742

Query: 808 ENSEGIAETSAVITVEEPTEENAEP 832
            N+ G A++ A I V E  +   +P
Sbjct: 743 RNTGGEAQSIADIAVMEAEQPQPQP 767



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 82/314 (26%), Positives = 125/314 (39%), Gaps = 41/314 (13%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P+F   P       G  I LE  +   P P++ W   G       N     E+      +
Sbjct: 7   PSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHF---SNREFFYENGR----A 59

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK------TGEKEPPQVIEP------- 740
            L I        G YT+ A N  GE S    + +K      T + E    +EP       
Sbjct: 60  QLVIDEAFLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQL 119

Query: 741 -LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796
            LK + V +G+ V L   +VG P P + W   ++PVK          GD H   +++   
Sbjct: 120 QLKDVSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGD-HCSLVIREAF 178

Query: 797 VKDEGVYTLKAENSEGIAET--SAVIT--------VEEPTEE----NAEPPLFINRFQEI 842
           ++D G Y + A NS G A +  S ++T        V +P E        PP F     +I
Sbjct: 179 LEDAGEYRVVAINSAGEASSKCSVIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDI 238

Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDS 901
              E    +    V+ +P P+I W+ NN EI+      +   D   ++L+I  V  + D 
Sbjct: 239 LAAEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHSVYRDDGVVKLIIEQVFPD-DK 297

Query: 902 GDYKCVASNSAGKS 915
           G Y   A N +G++
Sbjct: 298 GVYTAKAFNPSGEA 311



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 54/202 (26%), Positives = 90/202 (44%), Gaps = 13/202 (6%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
           E P    P  +++ R G+ + L A+V G P P + W  +           +     + ++
Sbjct: 5   EYPSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHFSNREFFYENGRAQL-VI 63

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEE--PTE-------ENAEP--PLFINRFQE 841
               +KD GVYTL A+N  G    S  + V+   P E        + EP  P    + ++
Sbjct: 64  DEAFLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKD 123

Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
           ++V E   ++L   +   P P + WY  +  +  S      F G++  LVI     E D+
Sbjct: 124 VSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLE-DA 182

Query: 902 GDYKCVASNSAGKSSHGARVTI 923
           G+Y+ VA NSAG++S    V +
Sbjct: 183 GEYRVVAINSAGEASSKCSVIV 204



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 62/234 (26%), Positives = 100/234 (42%), Gaps = 20/234 (8%)

Query: 704 QEGTYTVVAVNREGEASLPIVL---KIKTGE----KEPPQVIEPLKSMIVRQGESVILSA 756
           QE +   +A N   E    I+    +I TG+       P+ + P    IV QG  V    
Sbjct: 530 QETSILNIANNNASELHETIIANSGQISTGKPARRSSAPRFVSPFNGKIVDQGADVAFEG 589

Query: 757 QVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
            + G P P +   KN+   +P       S      +  LK     D G YT  A N+ G 
Sbjct: 590 IIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGA 649

Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN--- 870
           + T+A + V++    +  PP+F  R Q  +V     I L A V+  P P++ W+++N   
Sbjct: 650 SSTTADLVVKK----SIFPPVFGRRLQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPV 705

Query: 871 -EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            E + P     Q   G   +L+   +D   D+G +  VA N+ G++   A + +
Sbjct: 706 QEALRPGSYTLQQV-GPTCKLIFEQIDF-ADAGKFMIVARNTGGEAQSIADIAV 757



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 11/207 (5%)

Query: 399 VTIKKRLNPFEIFYTPVE-VRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWY 457
           VT++K++      Y+    V  G +   V+S  A  D +   V G+   I +T      +
Sbjct: 460 VTLQKQVTTSSSSYSSSTLVENGVSQSEVHSKSAHLDRSFKQVGGQAPEIAETKQ----F 515

Query: 458 VQKHLTEEKGWVPAQ---YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVE 514
            Q HL   +  +  Q    L   NN    L + +     ++    KP    +S AP FV 
Sbjct: 516 AQFHLANNQPPMIQQETSILNIANNNASELHETIIANSGQIST-GKPA--RRSSAPRFVS 572

Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574
               K    G+ V FE  ++GYP P++   +    ++P  +        N   + ++ V 
Sbjct: 573 PFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVS 632

Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVE 601
             DAG +T  A NAAG +S+T +L+V+
Sbjct: 633 TNDAGRYTATASNAAGASSTTADLVVK 659



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 48/198 (24%), Positives = 75/198 (37%), Gaps = 17/198 (8%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXX 1540
            P+   P  N+     + I+L     G P P+V W  DG      +  YEN R        
Sbjct: 7    PSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHFSNREFFYENGRAQLVIDEA 66

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQK-PVITISNEDIKQKHKV------------- 1586
                   Y   A N  GE   SC V ++ + P  T  +E       V             
Sbjct: 67   FLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKDVSV 126

Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
              G    +  VI G P PEVIWY     ++   ++ +  +     + I+E     + +Y 
Sbjct: 127  FEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLEDAGEYR 186

Query: 1645 IEASNTAGTSSVEVTLKV 1662
            + A N+AG +S + ++ V
Sbjct: 187  VVAINSAGEASSKCSVIV 204



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 4/90 (4%)

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            +I+G P PEV   KN  +L+ D E   ++      V+ +K +  + + +YT  ASN AG 
Sbjct: 590  IIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGA 649

Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
            SS    L V  K   P  PV  R +  +SV
Sbjct: 650  SSTTADL-VVKKSIFP--PVFGRRLQAQSV 676



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVAT 567
           P+F  +L+ +    G  +  + +V G P P + WF+    ++ +     Y          
Sbjct: 665 PVFGRRLQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCK 724

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           L+  ++   DAG F  VA+N  G A S  ++ V
Sbjct: 725 LIFEQIDFADAGKFMIVARNTGGEAQSIADIAV 757



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD--DNVAT 567
            P+FV  L+      G   +FEC V     P + W +    I  S   Q YY +  + +  
Sbjct: 1289 PLFVAPLKDIAVVSGQPARFECIVACDATPAVRWTKNNVPIDESG--QRYYPEYRNGLCR 1346

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            L +   +  DAG + C+A+N  G + +  +L V
Sbjct: 1347 LSLPVAYEGDAGKYCCLAENHLGHSQTCADLTV 1379



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 10/118 (8%)

Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIE 1129
            ++N S +D G Y+    +     S TA++ V +   PP    RLQ Q V++G +   + E
Sbjct: 628  LKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRRLQAQSVHRGERIILDAE 687

Query: 1130 LT-KGDALVRWFKDGSEIQFS---NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ++   +  V WFKD   +Q +       L   G   KL     D  DAG++     N+
Sbjct: 688  VSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKLIFEQIDFADAGKFMIVARNT 745



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 49/238 (20%), Positives = 92/238 (38%), Gaps = 27/238 (11%)

Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR-LPEFILVPANTDAYLTVEIPD 1222
            K   C++   G    E  +S+  + +   +PS+   L+ +  F   P   D  +  + P+
Sbjct: 85   KSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKDVSVFEGKPVRLDCVIVGQ-PE 143

Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
               +V WY     ++++  F L+      +L+IR+   +D  EY  V +++      K  
Sbjct: 144  P--EVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLEDAGEYRVVAINSAGEASSKCS 201

Query: 1283 VVEFPPKIVD-------------------YER---EYRIKRGSDVTLLVDYQAFPQPNDE 1320
            V+  P  I +                   +ER   +     G            P+PN +
Sbjct: 202  VIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDILAAEGEKCQFECAVSGDPRPNIK 261

Query: 1321 WIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            W VN++ I++  +      D     L I++V   D G+Y  +  N  G A    N+ +
Sbjct: 262  WFVNNREIVENPRVHSVYRDDGVVKLIIEQVFPDDKGVYTAKAFNPSGEAKCFSNLIV 319



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 29/158 (18%), Positives = 66/158 (41%), Gaps = 9/158 (5%)

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVVEFPPKIVDY 1293
            D E+  +   + K  + ++  + +D   YT    +A     +T  L V+   FPP     
Sbjct: 611  DGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRR 670

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC----KHTKPSIDSKSASLTIKK 1349
             +   + RG  + L  +    P+P   W  +++ +++      +T   +   +  L  ++
Sbjct: 671  LQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQV-GPTCKLIFEQ 729

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            ++  DAG + +   N  G A    ++ +++   P  +P
Sbjct: 730  IDFADAGKFMIVARNTGGEAQSIADIAVMEAEQPQPQP 767



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 5/94 (5%)

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
            ++ K    ++N+ TN + R+ A A N    + AS TT    V+K++ I  P   + L+  
Sbjct: 620  SLNKIVVELKNVSTNDAGRYTATASNA---AGASSTTADL-VVKKS-IFPPVFGRRLQAQ 674

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
            +    E I L     G P+P V W++D + ++ A
Sbjct: 675  SVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEA 708



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 39/216 (18%), Positives = 84/216 (38%), Gaps = 14/216 (6%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKATYE-NRXXX 1535
            +P    P      +   D+    I  G P P+V   ++  +L+        +Y  N+   
Sbjct: 567  APRFVSPFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVV 626

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVT 1593
                        Y   A N  G   T+  + +++   P +       +  H+ G+  ++ 
Sbjct: 627  ELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRRLQAQSVHR-GERIILD 685

Query: 1594 AVIEGIPPPEVIWYKNGNKLE---NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            A + G P P V W+K+   ++       Y +     T  +  +++  + + K+ I A NT
Sbjct: 686  AEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKLIFEQIDFADAGKFMIVARNT 745

Query: 1651 AG--TSSVEVTLKVYDKPS-KPEGPVIMREISRESV 1683
             G   S  ++ +   ++P  +P+  V   ++ + +V
Sbjct: 746  GGEAQSIADIAVMEAEQPQPQPQKHVSFIDVQKTTV 781


>UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10
            precursor; n=20; Mammalia|Rep: Immunoglobulin superfamily
            member 10 precursor - Homo sapiens (Human)
          Length = 2623

 Score =  120 bits (289), Expect = 4e-25
 Identities = 215/948 (22%), Positives = 368/948 (38%), Gaps = 101/948 (10%)

Query: 645  VDEGSDILLECRLVAIPEPDIAW--LFKGEEIVP-DENISVAIESDMHMYCSVLKITNVK 701
            +   SD  L C  V  P P I W  +  G ++    +N  V +  +       L I  V+
Sbjct: 1660 IPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN-----GTLSIQRVE 1714

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVG 760
                G Y   A N  G   L + L + +    PP+++E   K + V  G +V L  +  G
Sbjct: 1715 IQDRGQYLCSASNLFGTDHLHVTLSVVS---YPPRILERRTKEITVHSGSTVELKCRAEG 1771

Query: 761  NPRPTITWCKNNKPVKALPTKSDGDTHSIT------ILKPKKVKDEGVYTLKAENSEGIA 814
             P PT+TW   N+ V  +   S G   ++       +L    + D G Y   A N  G  
Sbjct: 1772 RPSPTVTWILANQTV--VSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGG-- 1827

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNN--E 871
            + S ++ +    +  A PP+ + + +++ V   G ++KL       P PS+ W  ++  E
Sbjct: 1828 QDSLLVKI----QVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTE 1883

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
            +     T ++ F   N  L I N+ S  D G Y+C+A++S G       +T++ E+VT  
Sbjct: 1884 VKPLQFTNSKLFLFSNGTLYIRNLASS-DRGTYECIATSSTGSERRVVMLTME-ERVTSP 1941

Query: 932  K---HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXX 984
            +     QK  E   G  ++L C  +     +  W    K +    HR    I        
Sbjct: 1942 RIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSL 2001

Query: 985  XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE---VKEKDVAILEV 1038
                    D GV  C+ +++    ++++  ++   P  I   Q F    +  KD  +   
Sbjct: 2002 FIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCK 2061

Query: 1039 EINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRK---------LYIRNTSVHDEGEYS 1088
               S   ++ W   DG +I    N    +  GH  +         LY     V +EG+Y+
Sbjct: 2062 ASGSPVPEISWSLPDGTMI---NNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYT 2118

Query: 1089 C----ILRDESCTAEVTVVELPPEI-ITRLQNQKVNKGNKATFEIELTKGD--ALVRWFK 1141
            C     L  +     +TV+   P I  +   N+++  G+ A  + E+T GD    + W  
Sbjct: 2119 CYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVT-GDPKPKIFWLL 2177

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS- 1195
              +++  S  I          L I    L D+GEY C   N     +K   +  V +P  
Sbjct: 2178 PSNDM-ISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPL 2236

Query: 1196 IN--FTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF-TLISDVKKR 1251
            IN  +T R         ++  +         + +V W    ++      + + I+  K  
Sbjct: 2237 INGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG 2296

Query: 1252 TLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF---PPKIVDYEREYRIKRGSDVT 1306
            TL IR     D  ++ CV  +   +S   +++EV+E    P     +  +   + G    
Sbjct: 2297 TLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTA 2356

Query: 1307 LLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
            L       P P   WI+ N         +   + + + S  I K    DAG Y+    N 
Sbjct: 2357 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNK 2416

Query: 1366 CGHADVEMNVTILDKP----SPPGKPNILEIDSSSINICWDE-PENTGNSTI-IYYVVEY 1419
             G+ +  + + I  KP      PG    +  +S S++   D  P+     T+   YVV+ 
Sbjct: 2417 VGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDR 2476

Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETK 1478
             +I+  ++I   N T        +K  ++Y    Y    +  +     T     V    +
Sbjct: 2477 PQIN-GKYILHDNGTLV------IKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTA 1525
            I      +P ++I T      +L C+  GVP+P++TW   D   L TA
Sbjct: 2530 I----TNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTA 2573



 Score =  105 bits (251), Expect = 2e-20
 Identities = 169/798 (21%), Positives = 304/798 (38%), Gaps = 64/798 (8%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P    ++ K   V  GS + L+CR    P P + W+   + +V +   S      +    
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSES--SQGSRQAVVTVD 1802

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGES 751
              L + N+  +  G Y  VA N  G+ SL + +++      PP ++E  + +IV   GES
Sbjct: 1803 GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAA---PPVILEQRRQVIVGTWGES 1859

Query: 752  VILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            + L     G P+P++ W  ++    KP++   +K    ++    ++     D G Y   A
Sbjct: 1860 LKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIA 1919

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             +S G      ++T+EE       P +     +   V     + L    T  P P I W 
Sbjct: 1920 TSSTGSERRVVMLTMEERV---TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWR 1976

Query: 868  RNNEIISPSETITQNFDG--ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
              ++ +   +    ++     N  L I +V +E DSG Y CVA N  G       V++ +
Sbjct: 1977 LPSKAVVDQQHRVGSWIHVYPNGSLFIGSV-TEKDSGVYLCVARNKMGDDLILMHVSLRL 2035

Query: 926  E--KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKW-------YHNKKEISGMDHR- 973
            +  K+   ++ +K  +   GK   ++C+ S +      W        +N  +     HR 
Sbjct: 2036 KPAKIDHKQYFRK--QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRT 2093

Query: 974  ---EIIQEGRXXXXXXXXXXXXDVGVI--KCIVKDQETSTMLVVKETIPEFIRKLQ-DFE 1027
                +   G             D        + KD E    L V    P   +  + +  
Sbjct: 2094 RRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKD-EMKVHLTVITAAPRIRQSNKTNKR 2152

Query: 1028 VKEKDVAILEVEINSE-TADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
            +K  D A+L+ E+  +    + W     ++I    ++Y F   G    L I    + D G
Sbjct: 2153 IKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG---SLTINKVKLLDSG 2209

Query: 1086 EYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKG-----NKATFE--IELTKGD 1134
            EY C+ R    D++   ++ VV  PP I     N+ V K      +K  F+   E T   
Sbjct: 2210 EYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSP 2269

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
             ++    D   +    +       K   L+I +  L D+ ++ C   N    ++L V+  
Sbjct: 2270 EVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLE 2329

Query: 1195 SINF----TLRLP--EFILVPANTDAYLTVEIP-DETLDVTWYKKKSV-IEDTEKFTLIS 1246
             +      T R P  E I+        L   +  +   ++ W         +  +     
Sbjct: 2330 VLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYL 2389

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDY-EREYRIKRGSD 1304
                 + II K T +D  +Y C   +      KL +  +   P I+ Y     +   G  
Sbjct: 2390 IASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGES 2449

Query: 1305 VTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            ++L       P+PN +W + S  ++ + +     I   + +L IK+    D G Y  + +
Sbjct: 2450 LSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQ 2509

Query: 1364 NNCGHADVEMNVTILDKP 1381
            N+ GH  + + V I+  P
Sbjct: 2510 NSVGHTLITVPVMIVAYP 2527



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 98/465 (21%), Positives = 183/465 (39%), Gaps = 25/465 (5%)

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +PD T+     +       T ++TL ++    TL   K    ++ +YTC   +     ++
Sbjct: 2074 LPDGTMINNAMQADDSGHRTRRYTLFNN---GTLYFNKVGVAEEGDYTCYAQNTLGKDEM 2130

Query: 1280 KVE--VVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            KV   V+   P+I    +   RIK G    L  +    P+P   W++ S  +      + 
Sbjct: 2131 KVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRY 2190

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDS 1394
            +  + + SLTI KV+  D+G Y     N  G       + ++ KP        N   I +
Sbjct: 2191 TFHA-NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKA 2249

Query: 1395 SSINIC---WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449
            +++      +D   E T +  +++ + +   +    + S   + K  T  I+N++ + S 
Sbjct: 2250 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 2309

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             F   A NE   S      E  ++++    ++P  EK    I  +  +   L C   G P
Sbjct: 2310 DFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEK----IVAQLGKSTALNCSVDGNP 2365

Query: 1510 QPKVTWYR-DGKKLKTAKATYE----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             P++ W   +G +      +Y+    +                Y+C A N  G +E   +
Sbjct: 2366 PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 2425

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKEYNITT 1623
            + I QKPVI ++      K   G+   +  V +GIP P + W   +G  ++  +      
Sbjct: 2426 LEIGQKPVI-LTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI 2484

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
                  + IKE        Y  +A N+ G + + V + +   P +
Sbjct: 2485 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 99/405 (24%), Positives = 161/405 (39%), Gaps = 56/405 (13%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            G +++  C  +G P+P + W       +KP Q         +  TL IR +   D GT+ 
Sbjct: 1857 GESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYE 1916

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            C+A ++ G       L +E  ++                           P   +   K 
Sbjct: 1917 CIATSSTGSERRVVMLTMEERVTS--------------------------PRIEAASQKR 1950

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVK 701
              V+ G  +LL C     P+P I W    + +V  ++    + S +H+Y +  L I +V 
Sbjct: 1951 TEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQH---RVGSWIHVYPNGSLFIGSVT 2007

Query: 702  KFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            +   G Y  VA N+ G+    + + L++K  + +  Q         V  G+   +  +  
Sbjct: 2008 EKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQ----VLHGKDFQVDCKAS 2063

Query: 760  GNPRPTITWCKNNKPV--KALPTKSDGD-THSITI-------LKPKKVKDEGVYTLKAEN 809
            G+P P I+W   +  +   A+     G  T   T+            V +EG YT  A+N
Sbjct: 2064 GSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQN 2123

Query: 810  SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YR 868
            + G  E    +TV       A P +  +      +K   T  L   VT +P P I W   
Sbjct: 2124 TLGKDEMKVHLTV-----ITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLP 2178

Query: 869  NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            +N++IS S  I +     N  L I  V   +DSG+Y CVA N +G
Sbjct: 2179 SNDMISFS--IDRYTFHANGSLTINKV-KLLDSGEYVCVARNPSG 2220



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 196/999 (19%), Positives = 355/999 (35%), Gaps = 91/999 (9%)

Query: 733  EPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI-- 789
            E P+++     S  +       L  + VGNP PTI W +    +     K +     +  
Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705

Query: 790  -TI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
             T+ ++  +++D G Y   A N  G       ++V      +  P +   R +EITV   
Sbjct: 1706 GTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVV-----SYPPRILERRTKEITVHSG 1760

Query: 848  GTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYK 905
             T++L  R    P P++TW   N+ +    S+   Q     +  LV+ N+ S  D G YK
Sbjct: 1761 STVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNL-SIYDRGFYK 1819

Query: 906  CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKW-YH 962
            CVASN  G+ S   ++ +       ++  ++      G+++ L C    T   S  W   
Sbjct: 1820 CVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLS 1879

Query: 963  NKKEISGMDH-REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI- 1020
            +  E+  +      +                D G  +CI      S   VV  T+ E + 
Sbjct: 1880 DGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVT 1939

Query: 1021 ------RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIR- 1072
                     +  EV   D  +L      E    ++W    + +  ++++       +   
Sbjct: 1940 SPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNG 1999

Query: 1073 KLYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
             L+I + +  D G Y C+ R    D+     V+ + L P  I   Q  +    +   F++
Sbjct: 2000 SLFIGSVTEKDSGVYLCVARNKMGDDLILMHVS-LRLKPAKIDHKQYFRKQVLHGKDFQV 2058

Query: 1129 EL-TKGDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQK---------LKIYDCDLDDAGE 1175
            +    G  +  + W   DG+ I  +N +Q    G + +         L      + + G+
Sbjct: 2059 DCKASGSPVPEISWSLPDGTMI--NNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGD 2116

Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWY 1230
            Y+C     +G  +    LTV   +            + A   A L  E+  D    + W 
Sbjct: 2117 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWL 2176

Query: 1231 --KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF 1286
                  +    +++T  ++    +L I K    D  EY CV  +     T   K++VV  
Sbjct: 2177 LPSNDMISFSIDRYTFHAN---GSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSK 2233

Query: 1287 PPKIVD-YEREYRIK----RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-S 1340
            PP I   Y     IK    R S        +  P P   WI+   I     +    I   
Sbjct: 2234 PPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVH 2293

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KP---SPPGKPNILEIDS 1394
            K+ +L I+ V  +D+  +     N  G + + + + +L+   +P   +P  +  + ++  
Sbjct: 2294 KNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGK 2353

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSYRFR 1452
            S+   C    +      II+ +            S + +  +  S    KT    + ++R
Sbjct: 2354 STALNC--SVDGNPPPEIIWILPNGTRFSNGPQ-SYQYLIASNGSFIISKTTREDAGKYR 2410

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A N+V   +     E    I +  +        +K I+    E + L C+  G+P+P 
Sbjct: 2411 CAARNKVGYIEKLVILE----IGQKPVILTYAPGTVKGIS---GESLSLHCVSDGIPKPN 2463

Query: 1513 VTW-----YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
            + W     Y   +     K    +                Y C A N  G    +  V I
Sbjct: 2464 IKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 2523

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL----ENDKEYNITT 1623
               P    +        + G  + +  V  G+P PE+ W    + L      ++ +    
Sbjct: 2524 VAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQ 2583

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
                  + I+  + S S  Y   A N  G+      ++V
Sbjct: 2584 LHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 100/441 (22%), Positives = 159/441 (36%), Gaps = 50/441 (11%)

Query: 519  KHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577
            K    G T   +C+V G P+P+I W      +I  S D   ++ +    +L I +V   D
Sbjct: 2151 KRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN---GSLTINKVKLLD 2207

Query: 578  AGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF 636
            +G + CVA+N +G  +   +L +V  P   +G                   +++      
Sbjct: 2208 SGEYVCVARNPSGDDTKMYKLDVVSKPPLING-------------LYTNRTVIKATAVRH 2254

Query: 637  SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
            SKK              +CR    P P++ W+      +        I    +     L+
Sbjct: 2255 SKKH------------FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKN---GTLE 2299

Query: 697  ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVILS 755
            I NV+      +  VA N  GE+ L + L++    +  P    P    IV Q G+S  L+
Sbjct: 2300 IRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR-PTFRNPFNEKIVAQLGKSTALN 2358

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSE 811
              V GNP P I W   N    +   +S         S  I K  + +D G Y   A N  
Sbjct: 2359 CSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTR-EDAGKYRCAARNKV 2417

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN--PVPSITWYRN 869
            G  E   ++       E  + P+ +  +   TVK      L      +  P P+I W   
Sbjct: 2418 GYIEKLVIL-------EIGQKPVILT-YAPGTVKGISGESLSLHCVSDGIPKPNIKWTMP 2469

Query: 870  NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            +  +     I   +   +   ++    +  D G+Y C A NS G +     V I      
Sbjct: 2470 SGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529

Query: 930  FVKHLQKSYETEEGKTVILEC 950
                  +S  T  G    L C
Sbjct: 2530 ITNRPPRSIVTRTGAAFQLHC 2550



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 77/292 (26%), Positives = 111/292 (38%), Gaps = 28/292 (9%)

Query: 634  PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PTF      + V + G    L C +   P P+I W+            S   +S  ++  
Sbjct: 2337 PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPN-----GTRFSNGPQSYQYLIA 2391

Query: 693  S--VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QG 749
            S     I+   +   G Y   A N+ G     ++L+I  G+K  P ++      +    G
Sbjct: 2392 SNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEI--GQK--PVILTYAPGTVKGISG 2447

Query: 750  ESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLK 806
            ES+ L     G P+P I W   +  V   P    K     +   ++K     D G Y  K
Sbjct: 2448 ESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICK 2507

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT 865
            A+NS G      +ITV  P    A PP   NR     V   G   +L       P P IT
Sbjct: 2508 AQNSVG----HTLITV--PVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEIT 2561

Query: 866  WYRNNEIISPSETITQNFDGENIEL----VITNVDSEIDSGDYKCVASNSAG 913
            W   +  +  + +  +    E + L    VI N  +  DSG YKC A N  G
Sbjct: 2562 WEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTS-DSGIYKCTAKNPLG 2612



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 86/406 (21%), Positives = 156/406 (38%), Gaps = 39/406 (9%)

Query: 1288 PKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSAS 1344
            P+IV  +   + I   SD  L  +    P P   W  + +   + K K         + +
Sbjct: 1648 PRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGT 1707

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            L+I++VE  D G Y     N  G   + + ++++  P     P ILE  +  I +     
Sbjct: 1708 LSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYP-----PRILERRTKEITV----- 1757

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD- 1463
             ++G++  +    E +   T  WI + N T    S Q  +           ++ + I D 
Sbjct: 1758 -HSGSTVELKCRAEGRPSPTVTWI-LANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDR 1815

Query: 1464 -------ASETTEYYKVIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
                   ++   +   ++K   I +P V  E+  + I     E ++L C   G PQP V 
Sbjct: 1816 GFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVY 1875

Query: 1515 W-YRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
            W   DG ++K  + T       +                Y+CIA +  G  E   V+   
Sbjct: 1876 WVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGS-ERRVVMLTM 1934

Query: 1569 QKPVITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-- 1623
            ++ V +   E   QK      GD+ L+     G P P+++W +  +K   D+++ + +  
Sbjct: 1935 EERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMW-RLPSKAVVDQQHRVGSWI 1993

Query: 1624 -KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
                   + I  +    S  Y   A N  G   + + + +  KP+K
Sbjct: 1994 HVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAK 2039



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 4/83 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            GSTV+ +C+ EG P P +TW    QT + + SQ  +      +  TLV+  +   D G +
Sbjct: 1760 GSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVD-GTLVLHNLSIYDRGFY 1818

Query: 582  TCVAKNAAGFASSTTEL-IVEAP 603
             CVA N  G  S   ++ ++ AP
Sbjct: 1819 KCVASNPGGQDSLLVKIQVIAAP 1841



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 17/184 (9%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + L C    IP+P+I W      +V    I+   +  +H     L I     +  G 
Sbjct: 2447 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQING--KYILHDN-GTLVIKEATAYDRGN 2503

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTI 766
            Y   A N  G   + + + I      PP++   P +S++ R G +  L    +G P+P I
Sbjct: 2504 YICKAQNSVGHTLITVPVMIVA---YPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 2560

Query: 767  TWCKNNKPVKALPTKSDGDTH--------SITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            TW   +  +  L T S   TH           +++  +  D G+Y   A+N  G    + 
Sbjct: 2561 TWEMPDHSL--LSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAAT 2618

Query: 819  VITV 822
             I V
Sbjct: 2619 YIQV 2622



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 15/209 (7%)

Query: 1497 EDIELTCIFGGVPQPKVTW-YRDGKKL-----------KTAKATYENRXXXXXXXXXXXX 1544
            +D ++ C   G P P+++W   DG  +           +T + T  N             
Sbjct: 2054 KDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAE 2113

Query: 1545 XXXYKCIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
               Y C A N  G+ E    +  I   P I  SN+  K + K GD  ++   + G P P+
Sbjct: 2114 EGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNK-RIKAGDTAVLDCEVTGDPKPK 2172

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            + W    N + +      T     S + I ++K   S +Y   A N +G  +    L V 
Sbjct: 2173 IFWLLPSNDMISFSIDRYTFHANGS-LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVV 2231

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLD 1692
             KP    G    R + + +     K   D
Sbjct: 2232 SKPPLINGLYTNRTVIKATAVRHSKKHFD 2260



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 3/83 (3%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV---ATLVIREVFPED 577
            T  G+  Q  C   G P+P+ITW      +  +   +  +  + +    TLVI+     D
Sbjct: 2540 TRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSD 2599

Query: 578  AGTFTCVAKNAAGFASSTTELIV 600
            +G + C AKN  G   + T + V
Sbjct: 2600 SGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQM 558
            T EE+  +P  +E    K T    G  +   C   G P+PQI W     A++        
Sbjct: 1933 TMEERVTSPR-IEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGS 1991

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            +       +L I  V  +D+G + CVA+N  G
Sbjct: 1992 WIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG 2023



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%)

Query: 524 GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           G T+   C   G P   I+W       + + S+D ++     N  TL I +V P+D G +
Sbjct: 588 GETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVL----NNGTLRILQVTPKDQGYY 643

Query: 582 TCVAKNAAG 590
            CVA N +G
Sbjct: 644 RCVAANPSG 652


>UniRef50_A0RX14 Cluster: Putative uncharacterized protein; n=1;
            Cenarchaeum symbiosum|Rep: Putative uncharacterized
            protein - Cenarchaeum symbiosum
          Length = 506

 Score =  118 bits (285), Expect = 1e-24
 Identities = 95/359 (26%), Positives = 154/359 (42%), Gaps = 25/359 (6%)

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE--ISRES 1682
            +KTS      L    +  Y I A N  G S       V +KP+  + PV +    +S  S
Sbjct: 40   QKTSYTHTA-LSSGETYSYKIYAKNQHGESRASNI--VSEKPAGTQSPVKLTATGLSPTS 96

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
              ++W  P D  GL++  Y+IE+    NN ++          +  +  L  + EY FRV 
Sbjct: 97   ARLDWFAPSDTVGLKIVSYSIERLT-SNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVF 155

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX------XXIDNESVYITWFPSEKNGG 1796
            A    G S   +SEP+V     D                     ++ V +TW     NGG
Sbjct: 156  AHLTQGVSSP-KSEPVVFTLTEDSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGG 214

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS---INTTYQFRIYARNEIGTSLPYTS 1853
            +PI  Y+++++ +G  ++         +R    +     T Y +R+YA N+IG+  P T 
Sbjct: 215  TPITGYRIDVRSDGN-YETIEADTGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPPTTE 273

Query: 1854 DDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909
                T  +     L  PS PRN   S S+S  + LKW EP  +GG+ I+ Y +E  +  G
Sbjct: 274  VSVTTAAEPEEPVLAAPSSPRNLEASASSSDRIDLKWVEPADDGGARISEYRLEADS--G 331

Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
              + +I   GG    +    +++  +  +R+ A N+ G S P+ + S   E+      P
Sbjct: 332  DGFERI--SGGRSTTYAHMGLEQDTKYTYRVYATNSEGTSSPSVAASATTEEEEEPEDP 388



 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 91/379 (24%), Positives = 151/379 (39%), Gaps = 22/379 (5%)

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            I W+ P  + G + T Y I+    D + +  + D +    +Y    L+    Y +++ A+
Sbjct: 4    ISWEEPTANDGPKATGYRIDYKTRDGD-YTTLIDDNGQKTSYTHTALSSGETYSYKIYAK 62

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
            N  G S A  S  +  K A    +          +   S  + WF      G  I+ Y +
Sbjct: 63   NQHGESRA--SNIVSEKPA---GTQSPVKLTATGLSPTSARLDWFAPSDTVGLKIVSYSI 117

Query: 1805 EIKQEGKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI--- 1859
            E       +            + +  L  +  Y+FR++A    G S P +     T+   
Sbjct: 118  ERLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLTED 177

Query: 1860 -GKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917
             GK +   P  P +  V+ S+   V+L W EP +NGG+PIT Y I+ ++  G   T    
Sbjct: 178  SGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRS-DGNYETIEAD 236

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL--EKHATVPSPPTAP--L 1973
             G +   +   +   + E  +R+ A N +G   PT   SV    E    V + P++P  L
Sbjct: 237  TGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPPTTEVSVTTAAEPEEPVLAAPSSPRNL 296

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033
            E     S+ +   W  P  DGGA +  Y +          +  G+    +  +    L +
Sbjct: 297  EASASSSDRIDLKWVEPADDGGARISEYRLEADSGDGFERISGGR----STTYAHMGLEQ 352

Query: 2034 NHTYMIRIYARNEIGLSEP 2052
            +  Y  R+YA N  G S P
Sbjct: 353  DTKYTYRVYATNSEGTSSP 371



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 64/276 (23%), Positives = 100/276 (36%), Gaps = 14/276 (5%)

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQK--LSINTTYQFRIYA 1841
            ++I+W     N G     Y+++ K     +                 LS   TY ++IYA
Sbjct: 2    LHISWEEPTANDGPKATGYRIDYKTRDGDYTTLIDDNGQKTSYTHTALSSGETYSYKIYA 61

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
            +N+ G S       +   G        P     +  +  S  L W  P    G  I +Y 
Sbjct: 62   KNQHGESRASNIVSEKPAGT-----QSPVKLTATGLSPTSARLDWFAPSDTVGLKIVSYS 116

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL-- 1959
            IE +      +      G S     + N++   E  FR+ A  T GVS P     V    
Sbjct: 117  IE-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLT 175

Query: 1960 -EKHATVPSPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
             +    V   P +P  +++  S+   V  +W  P  +GG P+ GY I +R       +E 
Sbjct: 176  EDSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRSDGNYETIE- 234

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                  +  +   D      Y  R+YA N+IG   P
Sbjct: 235  ADTGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPP 270



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 43/215 (20%), Positives = 79/215 (36%), Gaps = 7/215 (3%)

Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
            + W EP +N G   T Y I++KT  G  +T ++   G    +    +   +   ++I A+
Sbjct: 4    ISWEEPTANDGPKATGYRIDYKTRDG-DYTTLIDDNGQKTSYTHTALSSGETYSYKIYAK 62

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            N  G S    + ++  EK A   SP    L    +        W  P    G  ++ Y+I
Sbjct: 63   NQHGES---RASNIVSEKPAGTQSP--VKLTATGLSPTSARLDWFAPSDTVGLKIVSYSI 117

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
              R  +  ++++  K   +     + +L  +  Y  R++A    G+S P      F +  
Sbjct: 118  E-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLTE 176

Query: 2064 GEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREHN 2098
              G + +  P     +             W    N
Sbjct: 177  DSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSN 211



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%)

Query: 1384 PGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTS 1439
            P  P  L++ SSS   +++ W+EP N G + I  Y ++ +     E I      T    +
Sbjct: 186  PESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRSDGNYETIEADTGSTSRSYT 245

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
              +    + Y +R YA+N+  I     TTE   V    + + P +  P
Sbjct: 246  HTDRVAETEYTYRVYAINK--IGSGPPTTE-VSVTTAAEPEEPVLAAP 290



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 34/171 (19%), Positives = 73/171 (42%), Gaps = 10/171 (5%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEIDSS 1395
            + +  S T   + + +   YK+  +N   H +   +  + +KP+    P K     +  +
Sbjct: 38   NGQKTSYTHTALSSGETYSYKIYAKNQ--HGESRASNIVSEKPAGTQSPVKLTATGLSPT 95

Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRA 1453
            S  + W  P +T    I+ Y +E +      ++  +    + TS  + NL+T+  YRFR 
Sbjct: 96   SARLDWFAPSDTVGLKIVSYSIE-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRV 154

Query: 1454 YAVNEVDISDASETTEYYKVIKET-KIQSPTVEKP-LKNITTEPNEDIELT 1502
            +A     +S        + + +++ K    + E P    +T+  ++ + LT
Sbjct: 155  FAHLTQGVSSPKSEPVVFTLTEDSGKNVERSPESPGSLQVTSSSHDQVSLT 205


>UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome shotgun
            sequence; n=5; Tetraodontidae|Rep: Chromosome 7
            SCAF14703, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2095

 Score =  118 bits (284), Expect = 2e-24
 Identities = 172/815 (21%), Positives = 320/815 (39%), Gaps = 71/815 (8%)

Query: 725  LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784
            L +    +  P +++  ++  V  G+S+ L     G P PT+ W K+ +P   LP+ +  
Sbjct: 219  LSVMDPNESSPTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRP---LPSDARW 275

Query: 785  DTHSIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842
             T  +T   +   +++D G Y  +  NS G  E S  + V +P      P       + +
Sbjct: 276  -TRRLTGLTISDLRLEDSGSYACEVTNSFGSKEVSGQLHVIDPLRVTLSP-------KNL 327

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
                  T+     V  +P  +ITW+RN E+I P + I  +  G+N + +      +  SG
Sbjct: 328  KTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHI--SIQGQNNDTLQITAAQKFHSG 385

Query: 903  DYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWY 961
             Y+C AS     +   + + ++      V    ++     E  +++   + +   S  W 
Sbjct: 386  AYQCFASRKGHTAQDFSIILLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWT 445

Query: 962  HNKKEI----SGMDHREIIQEGRXXXXXXXXX-XXXDVGVIKCIVKDQETSTMLVVKETI 1016
             + + +    +    +  + +G              D GV +C+ ++   S     +  +
Sbjct: 446  LDDEPVVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINV 505

Query: 1017 --PEFIRKLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
              P  IR ++D   V  ++  I    I      + W +DG  +     +  FE  G +R 
Sbjct: 506  RGPPRIRPMRDMTAVAGRNTYITCRVIGYPYYSIKWLKDGMQLPDNHRQVVFE-NGTLRL 564

Query: 1074 LYIRNTSVHDEGEYSC-ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIE 1129
              ++  +  DEG Y C +L     +   TV   V++PP +I        + G        
Sbjct: 565  TDVQKGA--DEGTYLCSVLIQPQVSINQTVHVTVKVPP-LIQPFDIPSTSVGKLIYIACV 621

Query: 1130 LTKGDALVR--WFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGNSKC 1185
            ++ GD  +R  W KDG  I   +   + I+ K     L+I    L   G Y+C   N   
Sbjct: 622  VSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASN--- 678

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLD------VTWYKKKSVIED 1238
            TA     E  +  T+  P F++ P N D  Y    + + +++      V W   K V   
Sbjct: 679  TAATVSWERQLIVTVP-PRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNP 737

Query: 1239 TEKFTL-----ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE---VVEFPPKI 1290
             +   +     I  +   +L+IR   E+D+  Y C   +   +   +      V+ P  I
Sbjct: 738  QQYHPVPLTGRIQIMSNGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMI 797

Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI------DSKSAS 1344
              +      ++G    L    +        W     +I   ++ + SI      D   ++
Sbjct: 798  TSHPNTTMARKGQTKELNCTARGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVIST 857

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404
            L +   E  D+  +     N+ G     + +T+ + P PP +  + E+   S+N+ W + 
Sbjct: 858  LKLNPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPP-ELEVREVKDRSMNLRWIQ- 915

Query: 1405 ENTGNSTIIYYVVEYQEIDTTEW---ISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEV 1459
               GNS I  Y +EY+   +  W    + +NI  T  Q +I  L     Y  R Y+ N++
Sbjct: 916  RFDGNSIITSYDIEYKN-KSDSWDHMYTTRNISPTNNQANIVELHPACVYSIRMYSYNKI 974

Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
              S  S+  E     +E     P ++  L+ +T++
Sbjct: 975  GRSLPSK--ELTISTEEAPPDGPPMDVILQPMTSQ 1007



 Score =  105 bits (251), Expect = 2e-20
 Identities = 212/1054 (20%), Positives = 387/1054 (36%), Gaps = 117/1054 (11%)

Query: 1074 LYIRNTSVHDE-GEYSCILRD-------ESCTAEVTVV---ELPPEIITRLQNQKVNKGN 1122
            LYI      D    Y CI R        +S  A ++V+   E  P I+   Q  +V  G 
Sbjct: 185  LYISEVQKEDALSTYRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQ 244

Query: 1123 KATFEIELTKG---DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
              + E+    G   +  VRW KDG  +         + G    L I D  L+D+G Y+CE
Sbjct: 245  --SIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG----LTISDLRLEDSGSYACE 298

Query: 1180 VGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKS 1234
            V NS    + +  L V +P +  TL  P+ +    ++  + T  +       +TW++   
Sbjct: 299  VTNSFGSKEVSGQLHVIDP-LRVTLS-PKNLKTGISSTLFFTCSVEGSPEYTITWFRNTE 356

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIV 1291
            +I   +  + I      TL I    +     Y C     K  T     ++   +  P+IV
Sbjct: 357  LIVPDQHIS-IQGQNNDTLQITAAQKFHSGAYQC-FASRKGHTAQDFSIILLEDGTPRIV 414

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                E  +  G   +L+   +  P P+  W ++ + + +    K S  + S  LT+  V 
Sbjct: 415  SSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVSHVN 474

Query: 1352 NT-----DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
             +     D G+Y+    N+ G A+ +  + +   P      ++  +   +  I       
Sbjct: 475  VSSPHIRDGGVYRCVARNSAGSAEYQARINVRGPPRIRPMRDMTAVAGRNTYITC-RVIG 533

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
                +I +     Q  D    +  +N T   T +Q      +Y        +V I+    
Sbjct: 534  YPYYSIKWLKDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSINQTVH 593

Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525
             T          ++ P + +P    +T   + I + C+      P ++TW++DG+ +   
Sbjct: 594  VT----------VKVPPLIQPFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPG 643

Query: 1526 KA------TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV--ETSCVVGIQQKPVITISN 1577
             A      T +                 Y CIA N    V  E   +V +  + V+  +N
Sbjct: 644  SASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNN 703

Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN---ITTK---EKTSVIR 1631
            +D       G   ++   +EG PPP+V+W K+   + N ++Y+   +T +        + 
Sbjct: 704  QDC----IYGKAGVLNCSVEGYPPPKVMW-KHAKGVGNPQQYHPVPLTGRIQIMSNGSLL 758

Query: 1632 IKELKRSHSSKYTIEASNTAGTS-SVE---VTLKVYDK-PSKPEGPVIMREISRE-SVTI 1685
            I+ +       Y  +ASN  G+  S E   VT+K+     S P   +  +  ++E + T 
Sbjct: 759  IRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKGQTKELNCTA 818

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745
              + P+             +  P  +  I     D  + T  +          F   A N
Sbjct: 819  RGEQPIIIRWERGDTVIDAERNPRYSITINKKG-DEVISTLKLNPAERGDSVFFSCHAIN 877

Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
              G    L    + ++   D P           + + S+ + W     +G S I  Y +E
Sbjct: 878  SYGEGRGLIQ--LTVQEPPDPPE-----LEVREVKDRSMNLRWI-QRFDGNSIITSYDIE 929

Query: 1806 IKQEGKKWKXXXXX-----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
             K +   W               A I +L     Y  R+Y+ N+IG SLP     ++TI 
Sbjct: 930  YKNKSDSWDHMYTTRNISPTNNQANIVELHPACVYSIRMYSYNKIGRSLP---SKELTIS 986

Query: 1861 KTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKT----VKGKSWTK 1914
                PP   P + ++   TS+S+ + W  P+       I  Y I ++       G+    
Sbjct: 987  TEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGYQIGYRENGPGSNGQYSIV 1046

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV--------SLPTESQSVRLEKHATV- 1965
             +   G    + ++N+K+  +    + A N  G         +   E +  R ++ + + 
Sbjct: 1047 EMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSTEINATTLEDEDARKQRPSAIT 1106

Query: 1966 -------PSPPTAPLEIRMVG--SNIVMTSWG-TPEWDGGAPLLGYNIAIRDV-TKTMWM 2014
                   P P   P  +R +   S+  + +W   P       L GY +    + +   W 
Sbjct: 1107 DSYPPLFPVPSEPPQNVRAISVTSDEAVITWSEPPRLTLHGVLKGYRVVFWSLFSNGEWG 1166

Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            E+  +     +  +R L +   Y +++ A  + G
Sbjct: 1167 EMQNITTTREQVELRGLEKFTNYSVQVLAYTQAG 1200



 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 177/845 (20%), Positives = 320/845 (37%), Gaps = 96/845 (11%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PT     +A  V  G  I L C     P P + WL  G  +  D   +  +         
Sbjct: 229  PTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG------- 281

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L I++++    G+Y     N  G   +   L +     +P +V    K++      ++ 
Sbjct: 282  -LTISDLRLEDSGSYACEVTNSFGSKEVSGQLHVI----DPLRVTLSPKNLKTGISSTLF 336

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             +  V G+P  TITW +N + +      S  G  +    +   +    G Y   A     
Sbjct: 337  FTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQKFHSGAYQCFASRKGH 396

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE- 871
             A+  ++I +E+ T      P  ++ F E  V       L+      P PSITW  ++E 
Sbjct: 397  TAQDFSIILLEDGT------PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEP 450

Query: 872  IISPSETITQNF---DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            ++  S   T  +   DG  +  V  +     D G Y+CVA NSAG + + AR  I+V   
Sbjct: 451  VVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQAR--INVRGP 508

Query: 929  TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986
              ++ + +      G+   + C+       S KW  +  ++   +HR+++ E        
Sbjct: 509  PRIRPM-RDMTAVAGRNTYITCRVIGYPYYSIKWLKDGMQLPD-NHRQVVFE-NGTLRLT 565

Query: 987  XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA-ILEVEINSETA 1045
                  D G   C V  Q   ++        +    +Q F++    V  ++ +     + 
Sbjct: 566  DVQKGADEGTYLCSVLIQPQVSINQTVHVTVKVPPLIQPFDIPSTSVGKLIYIACVVSSG 625

Query: 1046 D----VVWERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA-- 1098
            D    + W +DG+ I P   +    E +  +  L I   ++   G Y+CI  + + T   
Sbjct: 626  DMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSW 685

Query: 1099 -EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKD---GSEIQF----- 1148
                +V +PP  + +  NQ    G        +       V W      G+  Q+     
Sbjct: 686  ERQLIVTVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPL 745

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208
            +  IQ+  +G    L I     +D G Y C+  N   + I    +   + T+++P  I  
Sbjct: 746  TGRIQIMSNG---SLLIRHVLEEDRGYYLCQASNGVGSDISREHD---HVTVKIPAMITS 799

Query: 1209 PANTDAY---LTVEI-----PDETLDVTWYKKKSVI--EDTEKFTLISDVKK----RTLI 1254
              NT       T E+      ++ + + W +  +VI  E   ++++  + K      TL 
Sbjct: 800  HPNTTMARKGQTKELNCTARGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLK 859

Query: 1255 IRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYR------IKRGSD 1304
            +      D   ++C  +    + +   +L V+    PP++   E + R      I+R   
Sbjct: 860  LNPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPPELEVREVKDRSMNLRWIQRFDG 919

Query: 1305 VTLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL- 1362
             +++  Y   +   +D W           +T  +I   +    I  VE   A +Y +R+ 
Sbjct: 920  NSIITSYDIEYKNKSDSW--------DHMYTTRNISPTNNQANI--VELHPACVYSIRMY 969

Query: 1363 -ENNCGHADVEMNVTILDKPSPPGKPN---ILE-IDSSSINICWDEP-ENTGNSTIIYYV 1416
              N  G +     +TI  + +PP  P    IL+ + S SI + W  P +   N  I  Y 
Sbjct: 970  SYNKIGRSLPSKELTISTEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGYQ 1029

Query: 1417 VEYQE 1421
            + Y+E
Sbjct: 1030 IGYRE 1034



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 135/602 (22%), Positives = 226/602 (37%), Gaps = 65/602 (10%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P   +  PK       S +   C +   PE  I W    E IVPD++IS+  +++     
Sbjct: 317  PLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNN----- 371

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L+IT  +KF  G Y   A +R+G  +    + +   E   P+++      +V  GE  
Sbjct: 372  DTLQITAAQKFHSGAYQCFA-SRKGHTAQDFSIILL--EDGTPRIVSSFSERVVNPGEPF 428

Query: 753  ILSAQVVGNPRPTITWCKNNKPV-------KALPTKSDGDTHSITILKPKKVKDEGVYTL 805
             L     G P P+ITW  +++PV        +  T SDG T S   +    ++D GVY  
Sbjct: 429  SLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRC 488

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A NS G AE  A I V  P          I   +++T        +  RV   P  SI 
Sbjct: 489  VARNSAGSAEYQARINVRGPPR--------IRPMRDMTAVAGRNTYITCRVIGYPYYSIK 540

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVTID 924
            W ++   +  +    +    EN  L +T+V    D G Y C V        +    VT+ 
Sbjct: 541  WLKDGMQLPDNH---RQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSINQTVHVTVK 597

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGMDHREIIQEGR- 980
            V  +     +     T  GK + + C  S     +   W+ + + I       +  E + 
Sbjct: 598  VPPLIQPFDIP---STSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKD 654

Query: 981  -XXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAIL 1036
                           G   CI  +   +      ++    P F+ +  + +       +L
Sbjct: 655  FMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNNQDCIYGKAGVL 714

Query: 1037 EVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIR-----KLYIRNTSVHDEGEYSC- 1089
               +       V+W+    +  P++  +     G I+      L IR+    D G Y C 
Sbjct: 715  NCSVEGYPPPKVMWKHAKGVGNPQQ-YHPVPLTGRIQIMSNGSLLIRHVLEEDRGYYLCQ 773

Query: 1090 ----ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGD--ALVRWFKD 1142
                +  D S   +   V++P  I +        KG   T E+  T +G+   ++RW + 
Sbjct: 774  ASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKGQ--TKELNCTARGEQPIIIRWERG 831

Query: 1143 GSEIQFSNH--IQLTIDGKKQK----LKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192
             + I    +    +TI+ K  +    LK+   +  D+  +SC      G  +    LTV+
Sbjct: 832  DTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDSVFFSCHAINSYGEGRGLIQLTVQ 891

Query: 1193 EP 1194
            EP
Sbjct: 892  EP 893



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 77/344 (22%), Positives = 134/344 (38%), Gaps = 23/344 (6%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IES 686
           +LE   P        + V+ G    L C     P P I W    E +V D     +    
Sbjct: 405 LLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTL 464

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
              +  S + +++      G Y  VA N  G A     + +    + PP+ I P++ M  
Sbjct: 465 SDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINV----RGPPR-IRPMRDMTA 519

Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
             G +  ++ +V+G P  +I W K+   +     +   +  ++ +   +K  DEG Y   
Sbjct: 520 VAGRNTYITCRVIGYPYYSIKWLKDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCS 579

Query: 807 AENSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SI 864
                 ++    V +TV+        PPL I  F   +      I +   V+   +P  I
Sbjct: 580 VLIQPQVSINQTVHVTVK-------VPPL-IQPFDIPSTSVGKLIYIACVVSSGDMPIRI 631

Query: 865 TWYRNNEIISPSETITQNFDGENI--ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
           TW+++ + I P        + ++    L IT V  +  +G+Y C+ASN+A   S   ++ 
Sbjct: 632 TWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLK-HNGNYTCIASNTAATVSWERQLI 690

Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNK 964
           + V     V+    + +   GK  +L C        K  W H K
Sbjct: 691 VTVPPRFVVQ--PNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAK 732



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 74/336 (22%), Positives = 133/336 (39%), Gaps = 25/336 (7%)

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678
            NITT  +   + ++ L++  +    + A   AG       L +  +   P  P  ++ + 
Sbjct: 1170 NITTTREQ--VELRGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDLPGPPAGIKAVP 1227

Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736
             S  SV + W PP    G+ + KY I    P + +      + + ++  Y I  L+   +
Sbjct: 1228 SSPSSVVVSWLPPNKPNGI-IRKYTIYCSSPGSGQPAPSEYEANPEMLFYRITHLSRGKQ 1286

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796
            Y     A    G      S  + ++ A  VP+              +V   W    +   
Sbjct: 1287 YHIWAAAVTTAGKGNF--SSKVTVEPAGKVPAKILSFGG-------TVTTPWMKEVRLPC 1337

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852
            S + +    IK   K  +         ++ Q LS N T   R     + G    T+    
Sbjct: 1338 SSVGEPAPTIKWT-KDSEDSAVPVTSDSQRQVLS-NGTLVLRSVKAEDSGYYTCTATNTL 1395

Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
              D I +   +  PP QPR  V + STS S+TL W  P  NGGS I  +++++     + 
Sbjct: 1396 GFDTIIVNLVVQVPPDQPRLTVSTTSTS-SITLAWI-PGDNGGSSIRGFVLQYSVDNTEE 1453

Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
            W + V +  +     ++N++       +++A+N+VG
Sbjct: 1454 W-RDVFISSTERSFKLDNLRCGTWYKVKLAAKNSVG 1488



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 16/167 (9%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAG 1652
            G P P + W K+      D    +T+  +  V+      ++ +K   S  YT  A+NT G
Sbjct: 1341 GEPAPTIKWTKDSE----DSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLG 1396

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
              ++ V L V   P +P   + +   S  S+T+ W P  D+GG  +  + ++    +   
Sbjct: 1397 FDTIIVNLVVQVPPDQPR--LTVSTTSTSSITLAWIPG-DNGGSSIRGFVLQYSVDNTEE 1453

Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
            W  V  +     ++ +  L     Y  ++ A+N VG    SE +E++
Sbjct: 1454 WRDVF-ISSTERSFKLDNLRCGTWYKVKLAAKNSVGSGRISEIIEAK 1499



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 5/137 (3%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            +IT++ + ++      AV   G+ +    + ++   K P +++    ++     + V L 
Sbjct: 1277 RITHLSRGKQYHIWAAAVTTAGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKEVRLP 1336

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYTLKAENSE 811
               VG P PTI W K+++   A+P  SD     ++    +L+  K +D G YT  A N+ 
Sbjct: 1337 CSSVGEPAPTIKWTKDSED-SAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTL 1395

Query: 812  GIAETSAVITVEEPTEE 828
            G       + V+ P ++
Sbjct: 1396 GFDTIIVNLVVQVPPDQ 1412



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            TP    V+  C   G P P I W + +  + +  + D Q     +   TLV+R V  ED+
Sbjct: 1327 TPWMKEVRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNG--TLVLRSVKAEDS 1384

Query: 579  GTFTCVAKNAAGFASSTTELIVEAP 603
            G +TC A N  GF +    L+V+ P
Sbjct: 1385 GYYTCTATNTLGFDTIIVNLVVQVP 1409



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%)

Query: 516 LRPKHTPDG--STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573
           L PK+   G  ST+ F C VEG P   ITWFR T +I P Q   +   +++   +   + 
Sbjct: 322 LSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQK 381

Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601
           F   +G + C A      A   + +++E
Sbjct: 382 F--HSGAYQCFASRKGHTAQDFSIILLE 407



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--- 563
           ++ P FV +   +    G      C VEGYP P++ W     +  P Q   +        
Sbjct: 692 TVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRIQI 751

Query: 564 -NVATLVIREVFPEDAGTFTCVAKNAAG 590
            +  +L+IR V  ED G + C A N  G
Sbjct: 752 MSNGSLLIRHVLEEDRGYYLCQASNGVG 779



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 10/224 (4%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESV 752
            +++  ++KF   +  V+A  + G+     VL I+T E    PP  I+ + S       S 
Sbjct: 1178 VELRGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDLPGPPAGIKAVPSSPSSVVVSW 1237

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--TILKPKKVKDEGVYTLKAENS 810
            +   +  G  R    +C +    +  P++ + +   +   I    + K   ++   A  +
Sbjct: 1238 LPPNKPNGIIRKYTIYCSSPGSGQPAPSEYEANPEMLFYRITHLSRGKQYHIWAA-AVTT 1296

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G    S+ +TVE   +  A+   F        +KE   ++L       P P+I W +++
Sbjct: 1297 AGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKE---VRLPCSSVGEPAPTIKWTKDS 1353

Query: 871  EIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            E  + P  + +Q     N  LV+ +V +E DSG Y C A+N+ G
Sbjct: 1354 EDSAVPVTSDSQRQVLSNGTLVLRSVKAE-DSGYYTCTATNTLG 1396



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 4/98 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY---DDDNV 565
           P  V     +    G      C  +G P P ITW      +++ S      Y   D   V
Sbjct: 411 PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTV 470

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           + + +      D G + CVA+N+AG A     + V  P
Sbjct: 471 SHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGP 508



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 84/403 (20%), Positives = 143/403 (35%), Gaps = 42/403 (10%)

Query: 584  VAKNAAGFASSTTELIVEAPLSD----HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
            V  +A+G A  T + +    ++     H    T               ++  +PP F  +
Sbjct: 641  VPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQ 700

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH-MYCSVLKIT 698
            P  Q    G   +L C +   P P + W        P +   V +   +  M    L I 
Sbjct: 701  PNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRIQIMSNGSLLIR 760

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
            +V +   G Y   A N  G         +    K P  +     + + R+G++  L+   
Sbjct: 761  HVLEEDRGYYLCQASNGVGSDISREHDHVTV--KIPAMITSHPNTTMARKGQTKELNCTA 818

Query: 759  VGNPRPTITWCKNN-------KPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810
             G     I W + +        P  ++     GD    T+ L P +  D   ++  A NS
Sbjct: 819  RGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDSVFFSCHAINS 878

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
             G       +TV+EP +    P L +   ++ ++     ++ + R   N +  IT Y + 
Sbjct: 879  YGEGRGLIQLTVQEPPD---PPELEVREVKDRSM----NLRWIQRFDGNSI--ITSY-DI 928

Query: 871  EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS------NSAGKSSHGARVTID 924
            E  + S++    +   NI    TN  + I      CV S      N  G+S     +TI 
Sbjct: 929  EYKNKSDSWDHMYTTRNIS--PTNNQANIVELHPACVYSIRMYSYNKIGRSLPSKELTIS 986

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967
             E+                  VIL+  TS ++   W   KKE+
Sbjct: 987  TEEAP---------PDGPPMDVILQPMTSQSIRVTWRAPKKEL 1020



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDD-DNVAT 567
           P  ++      T  G  +   C V     P +ITW +    I P     +  +  D +++
Sbjct: 599 PPLIQPFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSS 658

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           L I +V  +  G +TC+A N A   S   +LIV  P
Sbjct: 659 LQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVP 694


>UniRef50_Q53EP0 Cluster: Fibronectin type III domain-containing
            protein 3B; n=32; Euteleostomi|Rep: Fibronectin type III
            domain-containing protein 3B - Homo sapiens (Human)
          Length = 1204

 Score =  117 bits (282), Expect = 3e-24
 Identities = 122/466 (26%), Positives = 197/466 (42%), Gaps = 36/466 (7%)

Query: 1597 EGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654
            EG  P EVI Y     + END  ++     +     +K LKRS   K+ + ASNT G S 
Sbjct: 499  EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSC 558

Query: 1655 --SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN-- 1710
               V V     D+P  P  P++   ++    +++W PP D+GG E+ KY +E  + ++  
Sbjct: 559  PSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEA 618

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
            N+W +VA      E Y    L     Y  R    +  G S+  ES P  ++T    P   
Sbjct: 619  NQW-EVAYSGSATE-YTFTHLKPGTLYKLRACCISTGGHSQCSESLP--VRTLSIAPGQC 674

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS 1830
                      ++ V++ W       G  + +Y VE+ +                 +  L 
Sbjct: 675  RPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLL 734

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
              T Y+FR+ A N+ G   PY+   +IT      PP Q +   +S +    V + W  P+
Sbjct: 735  PGTVYRFRVRALNDGGYG-PYSDVSEIT--TAAGPPGQCKAPCISCTPDGCVLVGWESPD 791

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
            S+ G+ I+ Y +E+   + +   +++  G       I ++    +   R+ A N  G   
Sbjct: 792  SS-GADISEYRLEWG--EDEESLELIYHGTDTRFE-IRDLLPAAQYCCRLQAFNQAGAG- 846

Query: 1951 PTESQSVRLEKHATVPSPPTA-------PLEIRMVG-SNIVMTSWGTPEWDGGAPLLGYN 2002
               S+ V  +  A+ P P +        PL+      S  ++ +W  P  + G+ +L Y 
Sbjct: 847  -PYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEP-CNNGSEILAYT 904

Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            I + D + T    VG    NT    ++DL    TY IRI A NEIG
Sbjct: 905  IDLGDTSIT----VG----NTTMHVMKDLLPETTYRIRIQAINEIG 942



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 101/438 (23%), Positives = 175/438 (39%), Gaps = 18/438 (4%)

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEA--SNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            D +Y I    +     +K+L+ +      + A  ++  G+ S  V+   +    +   P 
Sbjct: 326  DGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPP 385

Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLN 1732
             +   S+ S+T++WK P+D+G  ++T Y +E  E   N   +        + +C + KL 
Sbjct: 386  KLAHRSKSSLTLQWKAPIDNGS-KITNYLLEWDEGKRNSGFRQCFFGS--QKHCKLTKLC 442

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
                Y FR+ A+N +G S    S+ +V  T  ++P                V + W   E
Sbjct: 443  PAMGYTFRLAARNDIGTSG--YSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKPE 499

Query: 1793 KNGGSPIIDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
                  +I Y +EI+++     +            ++ L  +T Y+FR+ A N  G S P
Sbjct: 500  GCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCP 559

Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
                   T      PP++P   V    TS   ++KW  P+ NGGS I  Y++E      +
Sbjct: 560  SEVLVCTTSPDRPGPPTRP--LVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSE 617

Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
            +    V   GS  E+   ++K       R    +T G S  +ES  VR    A  P    
Sbjct: 618  ANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIA--PGQCR 675

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030
             P  +       V   W  P  + G  +  Y++ + +  + +  EV       L+  + +
Sbjct: 676  PPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE-PEDVASEV--YHGPELECTVGN 732

Query: 2031 LSENHTYMIRIYARNEIG 2048
            L     Y  R+ A N+ G
Sbjct: 733  LLPGTVYRFRVRALNDGG 750



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 6/138 (4%)

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL-E 1391
            P    +  + T+K ++ +    ++L   N  G +   +V +  T  D+P PP +P +   
Sbjct: 524  PKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGP 583

Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWISVKNITKTQTSIQNLKTNSSY 1449
            + S   ++ WD P++ G S I+ Y++E  +   +  +W    + + T+ +  +LK  + Y
Sbjct: 584  VTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLY 643

Query: 1450 RFRAYAVNEVDISDASET 1467
            + RA  ++    S  SE+
Sbjct: 644  KLRACCISTGGHSQCSES 661



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 4/113 (3%)

Query: 1358 YKLRLENNCGHADVEMNV---TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            ++L   N+ G +     V   T+ + P  P  P ++    + + + W +PE      +I 
Sbjct: 449  FRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVIT 508

Query: 1415 YVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            Y +E QE +       K   +  T +++NLK ++ Y+FR  A N    S  SE
Sbjct: 509  YTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSE 561



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 50/221 (22%), Positives = 81/221 (36%), Gaps = 8/221 (3%)

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREISRE 1681
            T   T++  +K+L    + +  I+A N  G       +K   +P  P  P +       +
Sbjct: 913  TVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQ 972

Query: 1682 SVTIEWKPPLDDG-GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
            S+ ++W          E   Y ++  E  N R+I +        TY +Q+L E   Y FR
Sbjct: 973  SLKLKWGDSNSKTHAAEDIVYTLQL-EDRNKRFISI--YRGPSHTYKVQRLTEFTCYSFR 1029

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800
            + A +  G  E   SE     T   VP           ++  S  I W       G P+ 
Sbjct: 1030 IQAASEAG--EGPFSETYTFSTTKSVPP-TIKAPRVTQLEGNSCEILWETVPSMKGDPVN 1086

Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
                 +     ++K          +I  L  NT Y+FR+ A
Sbjct: 1087 YILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCA 1127



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 9/163 (5%)

Query: 1782 ESVYITWFPSE-KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
            +S+ + W  S  K   +  I Y ++++   K++           ++Q+L+  T Y FRI 
Sbjct: 972  QSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQ 1031

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
            A +E G   P++     +  K++ P    PR   V++    S  + W    S  G P+ N
Sbjct: 1032 AASEAGEG-PFSETYTFSTTKSVPPTIKAPR---VTQLEGNSCEILWETVPSMKGDPV-N 1086

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942
            YI++    +   + ++    G      I  ++   +  FR+ A
Sbjct: 1087 YILQVLVGRESEYKQVYK--GEEATFQISGLQTNTDYRFRVCA 1127


>UniRef50_A7RGL5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 428

 Score =  117 bits (281), Expect = 4e-24
 Identities = 95/381 (24%), Positives = 168/381 (44%), Gaps = 22/381 (5%)

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
           +ATL  +    ED   +TCVA NA G  SS+ EL V+        E T            
Sbjct: 1   IATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPI 60

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP--EPDIAWLFKGEEIVPDEN--- 679
             +       T S KP+ ++  +G  +    R + +   EP++  L   +++ P++    
Sbjct: 61  GQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVI-DDVQPEDAGKY 119

Query: 680 --ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPP 735
             I+   + ++    ++      +   E       V  + E + P  +  + G  E   P
Sbjct: 120 KCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPEFMDKERGPIEGHAP 179

Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITIL 792
           ++I  ++ M + +GE  +++ +V G P P++ W K++KP+   + L    +G+  ++ + 
Sbjct: 180 KLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQ 239

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEP-----TEENAEPPLFINRFQEITVKEK 847
           K   ++DE +YT  A NS G   +SA + V+E      + E   PP  I    EI V+E 
Sbjct: 240 K-AILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEG 298

Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYK 905
              +   RV  +P P I WY+    I   +   I +  +     L+I N +   DSG YK
Sbjct: 299 EDARFDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTEL-TDSGKYK 357

Query: 906 CVASNSAGKSSHGARVTIDVE 926
            VA+N  G+ +    +T+  E
Sbjct: 358 VVATNEVGRETSRGELTVTEE 378



 Score =  112 bits (269), Expect = 1e-22
 Identities = 88/376 (23%), Positives = 162/376 (43%), Gaps = 32/376 (8%)

Query: 494 KLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
           +L V EKP  S  +S  P+    L     P G   + + +V G P+P++ WF+   +++ 
Sbjct: 33  ELQVDEKPEISAPESTTPVAETALI---VPIGQEAKLDARVTGSPKPEVEWFKDGKVVED 89

Query: 553 SQDFQMYYDDDN--VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610
           +  F +Y +D+   V +LVI +V PEDAG + C+A N  G   +   L ++        +
Sbjct: 90  AGRF-LYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEK 148

Query: 611 MTVXXXXXXXXXXXXADI-------LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663
           +               +        +EG  P    + +   + EG D ++ C +   PEP
Sbjct: 149 VEPTADVGVKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 208

Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG----EA 719
            + WL   + +  D+ ++     ++    + LK+       E  YT  A N  G     A
Sbjct: 209 SVEWLKDDKPLPRDQRLTPMYNGEV----ATLKLQKAILEDEALYTCTASNSLGSVSSSA 264

Query: 720 SLPI----VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
            L +    V+ I      PP +I PL  + V++GE      +V G+P+P I W K    +
Sbjct: 265 ELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPEIQWYKGTTEI 324

Query: 776 -----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
                  +  +++ + +S+ I+   ++ D G Y + A N  G   +   +TV E  + + 
Sbjct: 325 FDEDRFEIVEEAEDNLYSLIIVN-TELTDSGKYKVVATNEVGRETSRGELTVTEELQNSR 383

Query: 831 EPPLFINRFQEITVKE 846
              +F      +T+++
Sbjct: 384 IKMVFDGETCSLTIRD 399



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 85/323 (26%), Positives = 137/323 (42%), Gaps = 50/323 (15%)

Query: 705 EGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLK--SMIVRQGESVILSAQVVGN 761
           E  YT VA N  G  S    L++ +  E   P+   P+   ++IV  G+   L A+V G+
Sbjct: 14  EALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARVTGS 73

Query: 762 PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
           P+P + W K+ K V    + L  + +       ++   + +D G Y   A N +G  E  
Sbjct: 74  PKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAE 133

Query: 818 AVITVEEPTE---ENAEPPLFINRFQEITV-----KEKGTI-----KLVAR--------- 855
           A ++++E TE   E  EP   +   +E+T      KE+G I     KL+A          
Sbjct: 134 ANLSIKEETETAPEKVEPTADVGVKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEG 193

Query: 856 --------VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
                   VT  P PS+ W ++++ +   + +T  ++GE   L +     E D   Y C 
Sbjct: 194 EDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILE-DEALYTCT 252

Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKS----------YETEEGKTVILECQT--SHT 955
           ASNS G  S  A + +D + V  +     S           E +EG+    + +   S  
Sbjct: 253 ASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQ 312

Query: 956 VSTKWYHNKKEISGMDHREIIQE 978
              +WY    EI   D  EI++E
Sbjct: 313 PEIQWYKGTTEIFDEDRFEIVEE 335



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 23/231 (9%)

Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
           + E++      +K     +  AP  + ++RP    +G      C+V G P P + W +  
Sbjct: 157 VKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDD 216

Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
             +   Q     Y+ + VATL +++   ED   +TC A N+ G  SS+ EL V     D 
Sbjct: 217 KPLPRDQRLTPMYNGE-VATLKLQKAILEDEALYTCTASNSLGSVSSSAELQV-----DE 270

Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIA 666
              + +                E + P     P  +  V EG D   + R+   P+P+I 
Sbjct: 271 KGVVPISP--------------EPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPEIQ 316

Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
           W     EI  ++   +  E++ ++Y   L I N +    G Y VVA N  G
Sbjct: 317 WYKGTTEIFDEDRFEIVEEAEDNLYS--LIIVNTELTDSGKYKVVATNEVG 365



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 3/139 (2%)

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
           K   ++DE +YT  A N+ G   +SA + V+E  E +A           + V      KL
Sbjct: 7   KSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKL 66

Query: 853 VARVTRNPVPSITWYRNNEIISPSETI--TQNFDGENIELVITNVDSEIDSGDYKCVASN 910
            ARVT +P P + W+++ +++  +      ++ + E   LVI +V  E D+G YKC+A N
Sbjct: 67  DARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPE-DAGKYKCIAFN 125

Query: 911 SAGKSSHGARVTIDVEKVT 929
             G+    A ++I  E  T
Sbjct: 126 EKGEVEAEANLSIKEETET 144



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 46/182 (25%), Positives = 79/182 (43%), Gaps = 18/182 (9%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL-KTAKAT--YENR-XXXXXXXXXXXXXXXYKCIA 1552
            ED  +TC   G P+P V W +D K L +  + T  Y                   Y C A
Sbjct: 194  EDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTA 253

Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----------GDEWLVTAVIEGIPPP 1602
             N  G V +S  + + +K V+ IS E +     +          G++      ++G P P
Sbjct: 254  SNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQP 313

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAG--TSSVEV 1658
            E+ WYK   ++ ++  + I  + + ++  + I   + + S KY + A+N  G  TS  E+
Sbjct: 314  EIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATNEVGRETSRGEL 373

Query: 1659 TL 1660
            T+
Sbjct: 374  TV 375



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%)

Query: 474 LMDENNYTQYLQKKLNEKID--KLPVFEK---PTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528
           L DE  YT      L       +L V EK   P S E    P  +  L      +G   +
Sbjct: 243 LEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDAR 302

Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKN 587
           F+ +V+G P+P+I W++ T  I     F++  + +DN+ +L+I      D+G +  VA N
Sbjct: 303 FDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATN 362

Query: 588 AAGFASSTTELIVEAPLSDHGSEM 611
             G  +S  EL V   L +   +M
Sbjct: 363 EVGRETSRGELTVTEELQNSRIKM 386



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 51/210 (24%), Positives = 96/210 (45%), Gaps = 26/210 (12%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P+ I +++  ++ E + A++  E+  +    V W +D + + P+  +      G +  L 
Sbjct: 179  PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPL-PRDQRLTPMYNGEVATLK 237

Query: 1076 IRNTSVHDEGEYSCI----LRDESCTAEVTVVEL-----------PPEIITRLQNQKVNK 1120
            ++   + DE  Y+C     L   S +AE+ V E            PP+IIT L   +V +
Sbjct: 238  LQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQE 297

Query: 1121 GNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEY 1176
            G  A F++ + KG     ++W+K  +EI   +  ++  + +     L I + +L D+G+Y
Sbjct: 298  GEDARFDVRV-KGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKY 356

Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRL 1202
                  EVG       LTV E   N  +++
Sbjct: 357  KVVATNEVGRETSRGELTVTEELQNSRIKM 386



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKH---KVGDEWLVTAVIEGIPPP 1602
            Y C+A N  G V +S  + + +KP I+   S   + +      +G E  + A + G P P
Sbjct: 17   YTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARVTGSPKP 76

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            EV W+K+G  +E+   +     E+  V  + I +++   + KY   A N  G    E  L
Sbjct: 77   EVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANL 136

Query: 1661 KVYDK 1665
             + ++
Sbjct: 137  SIKEE 141



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 16/184 (8%)

Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-- 1269
            DA +T E+  +    V W K    +   ++ T + + +  TL ++K   +D+  YTC   
Sbjct: 195  DAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTAS 254

Query: 1270 --LLDAKSTTKLKVE---VVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
              L    S+ +L+V+   VV        PP I+    E  ++ G D    V  +  PQP 
Sbjct: 255  NSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPE 314

Query: 1319 DEWIV-NSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
             +W    ++I  + +       +    SL I   E TD+G YK+   N  G       +T
Sbjct: 315  IQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATNEVGRETSRGELT 374

Query: 1377 ILDK 1380
            + ++
Sbjct: 375  VTEE 378



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 20/199 (10%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P++I  ++  ++ +G  A    E+T K +  V W KD   +     +    +G+   LK+
Sbjct: 179  PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKL 238

Query: 1166 YDCDLDDAGEYSCEVGNS----KCTAILTVEE----PSINFTLRLPEFIL------VPAN 1211
                L+D   Y+C   NS      +A L V+E    P     +  P+ I       V   
Sbjct: 239  QKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEG 298

Query: 1212 TDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTC 1268
             DA   V +      ++ WYK  + I D ++F ++ + +    +LII      D  +Y  
Sbjct: 299  EDARFDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKV 358

Query: 1269 VLLD--AKSTTKLKVEVVE 1285
            V  +   + T++ ++ V E
Sbjct: 359  VATNEVGRETSRGELTVTE 377



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 10/139 (7%)

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR-------GS 1303
            TL  +  T +D+  YTCV  +A  +     E+ V+  P+I   E    +         G 
Sbjct: 3    TLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQ 62

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLR 1361
            +  L       P+P  EW  + K+++         D +    SL I  V+  DAG YK  
Sbjct: 63   EAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCI 122

Query: 1362 LENNCGHADVEMNVTILDK 1380
              N  G  + E N++I ++
Sbjct: 123  AFNEKGEVEAEANLSIKEE 141



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 22/100 (22%), Positives = 44/100 (44%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            PK++   R  +I  G D  +  +    P+P+ EW+ + K + + +   P  + + A+L +
Sbjct: 179  PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKL 238

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +K    D  +Y     N+ G       + + +K   P  P
Sbjct: 239  QKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISP 278



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 22/86 (25%), Positives = 41/86 (47%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G++ ++T  + G P P V W K+   L  D+        + + +++++      + YT  
Sbjct: 193  GEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCT 252

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            ASN+ G+ S    L+V +K   P  P
Sbjct: 253  ASNSLGSVSSSAELQVDEKGVVPISP 278



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 1071 IRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELP----PEIITRLQNQK--VNK 1120
            I  L  ++ ++ DE  Y+C+    L   S +AE+ V E P    PE  T +      V  
Sbjct: 1    IATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPI 60

Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYS 1177
            G +A  +  +T      V WFKDG  ++ +       D + +   L I D   +DAG+Y 
Sbjct: 61   GQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYK 120

Query: 1178 CEVGNSK 1184
            C   N K
Sbjct: 121  CIAFNEK 127



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 12/126 (9%)

Query: 1170 LDDAGEYSC----EVGNSKCTAILTVEE-PSINF---TLRLPEF-ILVPANTDAYLTVEI 1220
            L+D   Y+C     +G+   +A L V+E P I+    T  + E  ++VP   +A L   +
Sbjct: 11   LEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARV 70

Query: 1221 PDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTCVLLDAKSTT 1277
                  +V W+K   V+ED  +F  + D +    +L+I     +D  +Y C+  + K   
Sbjct: 71   TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEV 130

Query: 1278 KLKVEV 1283
            + +  +
Sbjct: 131  EAEANL 136


>UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1874

 Score =  116 bits (280), Expect = 5e-24
 Identities = 182/877 (20%), Positives = 326/877 (37%), Gaps = 73/877 (8%)

Query: 1224 TLDVTWYKKK-SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------------ 1270
            T ++TW+K +  ++ +  + +++SD +K  L I    E D  +Y+CV             
Sbjct: 130  TPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLRESDNGKYSCVARNALGMVFSSQA 187

Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
            + A+    L + VV   P+     ++  +   +DV L    +  P P+  W V+      
Sbjct: 188  MPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGS---- 243

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
                   I  ++  L I+ ++ +  G Y    ++N G       VT+   P  P +PN  
Sbjct: 244  ------RISGQNGELIIRGIQRS--GNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNAA 295

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449
             I S +I I W  P   G   +  Y V+Y+    TEW  + N+   Q+  +  L+  SSY
Sbjct: 296  SITSDAIKITW-HPR--GAHVVTSYEVQYRLKGKTEWQEITNVRGMQSLVVSGLRPFSSY 352

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGG 1507
             FR +AVN +  S  S   EY     ETK  S    +E    + T+     +      G 
Sbjct: 353  EFRVFAVNSLGRSRPSLMAEY--TTSETKPGSAPRNIEAMGVSDTSFKAGWLPPISANGR 410

Query: 1508 VPQPKVTWYRD-GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566
            +   ++ +  D  + +   +    +                ++ +A+N  G+   S VV 
Sbjct: 411  IRGYRLYYSLDLLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVA 470

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNITTKE 1625
            ++ +  +      ++          VT      P   +  Y    NK + D +  +    
Sbjct: 471  VKTQKGVPGQPRSVQLSVLSSTAIRVTWSPPRYPGDGIFGYDVYYNKSKQDMD-TVIGAF 529

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP-EGPVIMREISRESVT 1684
            + +   I  L      K  + A +  G   +   L       +P + P  ++  SR+S T
Sbjct: 530  QMNTKEIMGLTPYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTT 589

Query: 1685 IE--WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            +E  W PP  +    L  +   K+     R  K   VD    +  +  L++   Y   V 
Sbjct: 590  LEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKYLTVDATKTSVVLHNLDKFTNYFIWVQ 649

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            A    G  +   S+   + TA DVP+           ++ ++ + W P        I+ Y
Sbjct: 650  ASTKQG--DGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTKQDGKILGY 707

Query: 1803 KV---EIKQEGKKW--------KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851
             V    +  +G +         K           +  L+  TTYQ  + A    G     
Sbjct: 708  MVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARS 767

Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911
             +    T+ ++  PP         +  S  VTL W    +        Y    + ++G+ 
Sbjct: 768  VTRLAKTMAQSPDPPFVYLERASGDPIS-DVTLAWRTSATGVIEYKVRYAKSVRRLRGRD 826

Query: 1912 W----TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
                  K +       +   +++      +F +S     G S P  S+ + +      P 
Sbjct: 827  QGNLKMKEIKFKSHTTKQKFQSLANGIWYLFNVSLRTKAGWS-PETSRWIEIP-----PG 880

Query: 1968 PPTA-PLEIR--MVGSNIVMTSWGTPE-WDGGAPLLGYNIAIRDVTKTMWMEVGKV-DVN 2022
            PP+  PL +R   V S  V  +W  P+ W+ G P+LGY++      K   + V  V   N
Sbjct: 881  PPSGPPLNVRAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVTSPN 940

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
              K  ++ L +   Y +R+ A   +G+     + EPF
Sbjct: 941  IFKVVLKRLKKFREYEVRVRAIGMLGMG---PASEPF 974



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 77/303 (25%), Positives = 124/303 (40%), Gaps = 34/303 (11%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           PT +  PK         + + C +   P P + W +K   ++ +  I +        Y  
Sbjct: 1   PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTW-YKNGSVIRNSRIQIFTMP----YGG 55

Query: 694 VLKITNVK-KFQEGTYTVVAVNREG----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
           +++I  ++ K  + TY   A N  G    ++S  IV    T     P++ +       R 
Sbjct: 56  LIRIGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRS 115

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYT 804
           G+ V  +   VG P P ITW K+  P+      +   SDG    IT L+     D G Y+
Sbjct: 116 GDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRKLRITDLRE---SDNGKYS 172

Query: 805 LKAENSEGIAETS----AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
             A N+ G+  +S    A + +          P F  R Q+ TV     ++L      +P
Sbjct: 173 CVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSP 232

Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            PSI W  +   IS          G+N EL+I  +     SG+Y C+A ++ G+    A 
Sbjct: 233 TPSIVWEVDGSRIS----------GQNGELIIRGIQR---SGNYSCIADSNMGRVQAYAY 279

Query: 921 VTI 923
           VT+
Sbjct: 280 VTV 282



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 77/342 (22%), Positives = 130/342 (38%), Gaps = 55/342 (16%)

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDY 904
            +G + ++  VT +P+P++TWY+N  +I  S  +  T  + G    + I  + ++I    Y
Sbjct: 15   RGFVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGG---LIRIGPLRAKIHKATY 71

Query: 905  KCVASNSAGKSSHGARV----TIDVEKVTF---VKHLQKSYETEEGKTVILECQT--SHT 955
            +C A N  G     +      T   +   F    KH     +   G  V   C    + T
Sbjct: 72   ECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKH-PSFKQRRSGDDVTFTCAAVGTPT 130

Query: 956  VSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--------QET 1006
             +  W+ ++  I   D R  ++ +GR            D G   C+ ++        Q  
Sbjct: 131  PNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKYSCVARNALGMVFSSQAM 188

Query: 1007 STMLVVKETI------PEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPK 1059
               L +  T+      PEF  + QD  V  + DV +      S T  +VWE DG  I   
Sbjct: 189  PARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRIS-- 246

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119
                     G   +L IR   +   G YSCI       + +  V+    +  RL     +
Sbjct: 247  ---------GQNGELIIR--GIQRSGNYSCI-----ADSNMGRVQAYAYVTVRLLPFAPS 290

Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161
            + N A+   +  K    + W   G+ +  S  +Q  + GK +
Sbjct: 291  RPNAASITSDAIK----ITWHPRGAHVVTSYEVQYRLKGKTE 328



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 42/156 (26%), Positives = 60/156 (38%), Gaps = 21/156 (13%)

Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
           K    G  V F C   G P P ITWF+    I  +        D     L I ++   D 
Sbjct: 111 KQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDN 168

Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638
           G ++CVA+NA G   S+  +   A L  + +   V                    P F+ 
Sbjct: 169 GKYSCVARNALGMVFSSQAM--PARLFIYLTLSVVRS-----------------KPEFTL 209

Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
           +P+ + VD  +D+ L+C     P P I W   G  I
Sbjct: 210 RPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRI 245



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 13/182 (7%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX- 1540
            PTV    K+        + + C   G P P +TWY++G  ++ ++               
Sbjct: 1    PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIG 60

Query: 1541 ---XXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV--ITISNEDIKQKHKVGDEWL 1591
                      Y+C A N  G    +  T  V     KP     I+     ++ + GD+  
Sbjct: 61   PLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVT 120

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
             T    G P P + W+K+   +  ND   ++ +  +   +RI +L+ S + KY+  A N 
Sbjct: 121  FTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLRESDNGKYSCVARNA 178

Query: 1651 AG 1652
             G
Sbjct: 179  LG 180



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 18/227 (7%)

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
            + Q L+    Y F +  R + G S   +   +I  G    PP   R   VS   S SV +
Sbjct: 845  KFQSLANGIWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNVRAVAVS---STSVEV 901

Query: 1885 KWTEPES-NGGSPITNYIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
             W+ P+  N G PI  Y + +     +G    K VT   ++ +  ++ +K+  E   R+ 
Sbjct: 902  TWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVT-SPNIFKVVLKRLKKFREYEVRVR 960

Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
            A   +G+   +E    R ++          P   R VGS+ V+  W  P  D G      
Sbjct: 961  AIGMLGMGPASEPFIDRTKEDGKCHCRDVRP---RTVGSDWVILEWLPPRIDAGID---- 1013

Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
                  +T    + V  +  +   F ++ L  +  Y +R+ A N +G
Sbjct: 1014 ----TPLTHADEVRVDALTADVQTFKVQGLVPHMKYTVRLSASNAMG 1056



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%)

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P +T++ +D     + G  +++  V  G P P + WYKNG+ + N +   I T     +I
Sbjct: 1    PTVTLTPKDFAGVTR-GFVYMICNVT-GSPMPTLTWYKNGSVIRNSR-IQIFTMPYGGLI 57

Query: 1631 RIKELK-RSHSSKYTIEASNTAGTSSVE-VTLKVYDKPSKPEG 1671
            RI  L+ + H + Y  EA N  G    +  TL V+   +KP G
Sbjct: 58   RIGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAG 100


>UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep:
            Unc-40 protein - Caenorhabditis elegans
          Length = 1415

 Score =  115 bits (277), Expect = 1e-23
 Identities = 135/605 (22%), Positives = 230/605 (38%), Gaps = 51/605 (8%)

Query: 1479 IQSPTVEKPLKNITT------EPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE 1530
            + + TV   L  ITT      E  ++  L C+   + +P+V W +D +++     +    
Sbjct: 236  VTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV 295

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590
                             Y C A N+   ++ +  V ++  P IT +    K   +  D  
Sbjct: 296  GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAPPRIT-TRPTTKVAVETADVE 354

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            L        P   V WYKNG  +    EY +    +   +RI  + R+  + Y   A N 
Sbjct: 355  LECGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNR---LRILGVVRADQAIYQCIAEND 410

Query: 1651 AGT--SSVEVTLKVYDK---------PSKPEGPVIMREISRES--VTIEWKPPLDDGGLE 1697
             G+  +S ++ +   D          P     P+ +R  S  S  + +EW PP+   G  
Sbjct: 411  VGSEQASAQLLVDAPDSSSVAASSGVPMTSSAPLGLRSTSSGSRFINVEWDPPVQRNG-N 469

Query: 1698 LTKYAI--EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755
            + +Y I  + +  D  R I  +       +  +  L  +  Y+ RV A+N  G  +  +S
Sbjct: 470  IMRYHIFYKDNLIDRERMINSSST-----SATLTSLQPSTMYLIRVTAENEAGMGKFSDS 524

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKK 1812
              +       VP              E++ I W P   +GG P + YK+       E  +
Sbjct: 525  LKVTTNKEQAVPGKVASLTTTAT-GPETIDIRWSP--PSGGQPALRYKIFYSHDPLEKNE 581

Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR-N 1871
             +           +  +   T YQ RI A    G+ L   S D + +      PS P  N
Sbjct: 582  KETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGL---SSDTVKVRTQSDEPSAPPVN 638

Query: 1872 FVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930
                  +S SV + W EPE       IT Y +++KT    +    + +  +  E+ + N+
Sbjct: 639  IQAEADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYTMGNL 698

Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMTSWGT 1989
            +   + + R++  N  G    ++  S+             AP EIR   G + ++ SW  
Sbjct: 699  EPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAPREIRPHAGIDYILVSW-L 757

Query: 1990 PEWDGGAPLLGYNIAI-RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            P  D    + GY I     V  T   E  +V  +T ++ I  L     Y+I + A N +G
Sbjct: 758  PPADEQNLVRGYQIGWGLSVPDT---ETIRVTASTTQYKIARLHSERDYVISLRAFNNLG 814

Query: 2049 LSEPL 2053
               P+
Sbjct: 815  SGFPI 819



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 62/281 (22%), Positives = 107/281 (38%), Gaps = 21/281 (7%)

Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           +G      C + + P P   WL   E IV      +   S+       L+I++ +   EG
Sbjct: 161 KGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSN------TLEISSTQSRHEG 214

Query: 707 TYTVV---AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
           TY      A  R    +  + +  +T   E   +  P +  +V QG+  +L   V    R
Sbjct: 215 TYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTP-RLQVVEQGDEFLLECLVASLIR 273

Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           P + W K+++ +     +      S  ++    ++D G+YT +A N++   + +  + V 
Sbjct: 274 PQVRWLKDSRQIIVDGVRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVR 333

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            P      P        ++ V+              P   + WY+N E I  SE     F
Sbjct: 334 APPRITTRPT------TKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSE----YF 383

Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             E   L I  V    D   Y+C+A N  G     A++ +D
Sbjct: 384 VIEPNRLRILGV-VRADQAIYQCIAENDVGSEQASAQLLVD 423



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 13/191 (6%)

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           F   P+ Q V++G + LLEC + ++  P + WL    +I+ D    V I     +  S +
Sbjct: 247 FITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVD---GVRIR---RVGVSSI 300

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVIL 754
            ++       G YT  A N +      + ++++     PP++   P   + V   +  + 
Sbjct: 301 LVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRA----PPRITTRPTTKVAVETADVELE 356

Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
                  P   + W KN + +         + + + IL   +  D+ +Y   AEN  G  
Sbjct: 357 CGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNRLRILGVVRA-DQAIYQCIAENDVGSE 414

Query: 815 ETSAVITVEEP 825
           + SA + V+ P
Sbjct: 415 QASAQLLVDAP 425



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 1358 YKLRLE----NNCGHADVEMNV-TILDKPSPPGKPNILEIDSS-SINICWDEPENTG-NS 1410
            Y++R+E    N  G +   + V T  D+PS P      E DSS S+ + WDEPE    N 
Sbjct: 604  YQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQAEADSSTSVRVSWDEPEEESVNG 663

Query: 1411 TIIYYVVEY--QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             I  Y ++Y  +         V + T  + ++ NL+ N+ Y  R   VN
Sbjct: 664  EITGYRLKYKTKARGAKGNTLVIDATAREYTMGNLEPNTQYLIRMAVVN 712


>UniRef50_Q9Y2H6 Cluster: Fibronectin type-III domain-containing
            protein 3a; n=37; Euteleostomi|Rep: Fibronectin type-III
            domain-containing protein 3a - Homo sapiens (Human)
          Length = 1134

 Score =  115 bits (277), Expect = 1e-23
 Identities = 115/430 (26%), Positives = 181/430 (42%), Gaps = 34/430 (7%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMREISRESVTIEWK 1688
            +K L+RS   K+ + A N+ G S+    ++     DKP  P  P +  +I   S  I W 
Sbjct: 463  VKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWD 522

Query: 1689 PPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            PP D+GG  + KY +E  E  N N+W  +         +   +LN  C Y  RV   +  
Sbjct: 523  PPKDNGGATINKYVVEMAEGSNGNKWEMI--YSGATREHLCDRLNPGCFYRLRVYCISDG 580

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G  ++  SE ++++T    P              + + + W P   +GGSPI  Y VE+ 
Sbjct: 581  G--QSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMS 638

Query: 1808 Q-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
              E  + +           +  L    TY FR+ A N++G   P++  +K  I     PP
Sbjct: 639  PIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFG-PFS--EKCDITTAPGPP 695

Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
             Q +   V+  ++    + W  P SN G+ +T Y +E+  V+G    +I   G  +  + 
Sbjct: 696  DQCKPPQVTCRSATCAQVNWEVPLSN-GTDVTEYRLEWGGVEGS--MQICYCGPGL-SYE 751

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI--------RMV 1978
            I+ +        R+ A + VG      S+ V      +VP   T   EI           
Sbjct: 752  IKGLSPATTYYCRVQALSVVGAG--PFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 809

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
             S  +  SW  P  D G+ +L Y+I   D      + VGKV      + I +L  + TY 
Sbjct: 810  PSTCLAISWEKP-CDHGSEILAYSIDFGDKQS---LTVGKV----TSYIINNLQPDTTYR 861

Query: 2039 IRIYARNEIG 2048
            IRI A N +G
Sbjct: 862  IRIQALNSLG 871



 Score =  108 bits (260), Expect = 1e-21
 Identities = 104/428 (24%), Positives = 172/428 (40%), Gaps = 30/428 (7%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREISRESVTIEW 1687
            +I +L  +   K+ + A N  GTS     +  Y     PS P  PV+ +      ++++W
Sbjct: 365  KITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQW 423

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
              P      E   Y +E  E  +    K      D+  Y ++ L  + +Y F+VIA N  
Sbjct: 424  SKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDL-AYTVKNLRRSTKYKFKVIAYNSE 482

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G S    SE +   T  D P           I + S  ITW P + NGG+ I  Y VE+ 
Sbjct: 483  GKSN--PSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMA 540

Query: 1808 Q--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            +   G KW+             +L+    Y+ R+Y  ++ G S      + + +     P
Sbjct: 541  EGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS---AVSESLLVQTPAVP 597

Query: 1866 PS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
            P     PR  +     ++ + L+W  P  +GGSPI+ Y +E   ++ K   + V  G  V
Sbjct: 598  PGPCLPPR--LQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE-KDEPREVYQGSEV 654

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP--TAPLEIRMVGS 1980
             E  + ++       FR+ A N +G    +E   +      T P PP    P ++    +
Sbjct: 655  -ECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDI-----TTAPGPPDQCKPPQVTCRSA 708

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
                 +W  P    G  +  Y +    V  +  M++       L + I+ LS   TY  R
Sbjct: 709  TCAQVNWEVP-LSNGTDVTEYRLEWGGVEGS--MQICYCGPG-LSYEIKGLSPATTYYCR 764

Query: 2041 IYARNEIG 2048
            + A + +G
Sbjct: 765  VQALSVVG 772



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 111/462 (24%), Positives = 193/462 (41%), Gaps = 32/462 (6%)

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRS--HSSKYTIEASNTAGT-SSVEVTLKVYDKPSKPE 1670
            ++ K  ++   E+T+ I + +LK +  + +K   E ++  GT S  E+   +  +P  P 
Sbjct: 253  KDGKYKSVYVGEETN-ITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPN 311

Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730
             P I    ++ S+T++WK P D+G  ++  + +E  E   N       +    + + I K
Sbjct: 312  PPRIANR-TKNSLTLQWKAPSDNGS-KIQNFVLEWDEGKGNGEFCQCYMGSQ-KQFKITK 368

Query: 1731 LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
            L+      FR+ A+N  G S    SE ++  T+   PS                 ITW  
Sbjct: 369  LSPAMGCKFRLSARNDYGTSGF--SEEVLYYTSGCAPSMPASPVLT------KAGITWLS 420

Query: 1791 SE--KNGGSPI---IDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
             +  K  G+P    I Y +E+++E  G  +K           ++ L  +T Y+F++ A N
Sbjct: 421  LQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYN 480

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
              G S P    +  T       P +P   V  +  S S  + W  P+ NGG+ I  Y++E
Sbjct: 481  SEGKSNPSEVVEFTTCPDKPGIPVKPS--VKGKIHSHSFKITWDPPKDNGGATINKYVVE 538

Query: 1904 F-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
              +   G  W  I +  G+  EH  + +        R+   +  G S    S+S+ ++  
Sbjct: 539  MAEGSNGNKWEMIYS--GATREHLCDRLNPGCFYRLRVYCISDGGQS--AVSESLLVQTP 594

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
            A  P P   P       +  +   WG P  DGG+P+  Y++ +  + K    EV     +
Sbjct: 595  AVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREV--YQGS 652

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064
             ++  +  L    TY  R+ A N++G   P          PG
Sbjct: 653  EVECTVSSLLPGKTYSFRLRAANKMGFG-PFSEKCDITTAPG 693



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 68/286 (23%), Positives = 109/286 (38%), Gaps = 19/286 (6%)

Query: 1779 IDNESVYITWFPSEK--NGGSP------IIDYKVEIKQEGK--KWKXXXXXXXXXARIQK 1828
            I   +V +TW P     NG +       +  Y+V I   GK  K+K           +  
Sbjct: 213  IQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLND 272

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888
            L     Y  ++ A        P  ++   T+      P+ PR   ++  T  S+TL+W  
Sbjct: 273  LKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPR---IANRTKNSLTLQWKA 329

Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            P  N GS I N+++E+   KG          GS  +  I  +       FR+SA N  G 
Sbjct: 330  PSDN-GSKIQNFVLEWDEGKGNG-EFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGT 387

Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
            S    S+ V        PS P +P+ +   G   +   W  P        + Y + + + 
Sbjct: 388  S--GFSEEVLYYTSGCAPSMPASPV-LTKAGITWLSLQWSKPSGTPSDEGISYILEMEEE 444

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            T     +  K D   L + +++L  +  Y  ++ A N  G S P E
Sbjct: 445  TSGYGFK-PKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSE 489



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 5/138 (3%)

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL- 1390
            KP  D +  + T+K +  +    +K+   N+ G +   +V    T  DKP  P KP++  
Sbjct: 451  KPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKG 510

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSY 1449
            +I S S  I WD P++ G +TI  YVVE  E  +  +W  + +    +     L     Y
Sbjct: 511  KIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFY 570

Query: 1450 RFRAYAVNEVDISDASET 1467
            R R Y +++   S  SE+
Sbjct: 571  RLRVYCISDGGQSAVSES 588



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 1/91 (1%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTS 1439
            PS P  P + +   + +++ W +P  T +   I Y++E +E  +      K +      +
Sbjct: 403  PSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYT 462

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            ++NL+ ++ Y+F+  A N    S+ SE  E+
Sbjct: 463  VKNLRRSTKYKFKVIAYNSEGKSNPSEVVEF 493



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 48/227 (21%), Positives = 90/227 (39%), Gaps = 24/227 (10%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV-------- 1683
            IK L  + +    ++A +  G       +     PS P     ++EIS + +        
Sbjct: 752  IKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPS 811

Query: 1684 ---TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740
                I W+ P D G  E+  Y+I+  +  +    KV        +Y I  L  +  Y  R
Sbjct: 812  TCLAISWEKPCDHGS-EILAYSIDFGDKQSLTVGKVT-------SYIINNLQPDTTYRIR 863

Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPI 1799
            + A N +G      S  I +KT    P             ++++ + W   + K   +  
Sbjct: 864  IQALNSLGAGPF--SHMIKLKTKPLPPDPPRLECVA--FSHQNLKLKWGEGTPKTLSTDS 919

Query: 1800 IDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
            I Y ++++ +  ++           ++Q+L+ +T+Y+F I A NE G
Sbjct: 920  IQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAG 966


>UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel
           hemicentin protein; n=1; Danio rerio|Rep: PREDICTED:
           similar to novel hemicentin protein - Danio rerio
          Length = 841

 Score =  115 bits (276), Expect = 2e-23
 Identities = 102/425 (24%), Positives = 169/425 (39%), Gaps = 35/425 (8%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           T+Q    V G P PQ+ WF+    +   + +  +   +D    LVI       +G F CV
Sbjct: 252 TIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGVSLAEDGA--LVIGSASASHSGDFKCV 309

Query: 585 AKNAAGFASSTTEL-IVEAP----------------LSDHGSEMTVXXXXXXXXXXXXAD 627
           A N AG     T L ++E P                  DH    +               
Sbjct: 310 ATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYT 369

Query: 628 ILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
           I    PP  S     Q V    G ++ ++CR+   P P + W   GE + P+ +  V   
Sbjct: 370 IEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFL 429

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                   VL++ +V+    G Y  VA N  G  +    L I+          +   +++
Sbjct: 430 EKGQ----VLRVKSVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVV 485

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
           +  G   +L  +V G P PTITW K+N+P+ + P  +         +   + +D G YT 
Sbjct: 486 L--GFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQGGQSLRVAAARGEDAGAYTC 543

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +A N  G A     + +  P +   +  +     +E  V+  GT+ L       P P   
Sbjct: 544 RATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEPVTQ 603

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDS--GDYKCVASNSAGKSSHGARVTI 923
           W+++ ++++ +        G ++   + +VD+ + S  G Y CV SNSAG+      +TI
Sbjct: 604 WFKDGQLLNGN-----THSGLSVNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHLTI 658

Query: 924 DVEKV 928
            V  V
Sbjct: 659 QVPPV 663



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 131/574 (22%), Positives = 231/574 (40%), Gaps = 69/574 (12%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            GS+++L C +   P P + W   G+ I P       + S        LKI++V+      
Sbjct: 104  GSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPS------GSLKISDVRVVDSKL 157

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            YT  AVN  G  SL   L+++   +  P     LK++I   G++V+L   V G P P ++
Sbjct: 158  YTCSAVNPAGNVSLTYNLQVQAKPRIHP-APSTLKALI---GQTVVLPCVVQGEPSPQVS 213

Query: 768  WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV---EE 824
            W  N      LP  SD     +  ++  +  D G Y   A NS G      V+ V     
Sbjct: 214  WLHN-----GLPVASD----RMLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPA 264

Query: 825  PTEENAEPPLFINRFQE---ITVKEKGTIKLVAR----------VTRNPVPSITWYRNNE 871
            P     +  L ++  +    +++ E G + + +           V  N   S+      +
Sbjct: 265  PQVRWFKNGLEVHMERSEHGVSLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLK 324

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
            ++       QN  G+ + L I  V  +  +G + C A NSAG++     + +    V   
Sbjct: 325  VLETPGVYLQN--GKRL-LKIYRVQHD-HAGRFSCTAQNSAGEAKREYTIEVQAPPVISG 380

Query: 932  KHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEIS--GMDHREIIQEGRXXXXXXX 987
                +      G+ V ++C+ S     S +W H+ + +S  G  H E +++G+       
Sbjct: 381  TSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQ--VLRVK 438

Query: 988  XXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKE--KDVAILEVEINS 1042
                 D G+ +C+  +    +T    +  +  P      +D EV       A+L  E+  
Sbjct: 439  SVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEG 498

Query: 1043 -ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-- 1099
                 + W +D + I     +  + + G  + L +      D G Y+C   + + TA   
Sbjct: 499  IPLPTITWLKDNQPI-VSSPQLTYTQGG--QSLRVAAARGEDAGAYTCRATNPAGTAHRH 555

Query: 1100 -VTVVELPPEI---ITRL----QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149
                + +PP+I    T L    + +KV      T    L KG  + + +WFKDG  +  +
Sbjct: 556  YTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSC-LAKGFPEPVTQWFKDGQLLNGN 614

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
             H  L+++     L + +  L   G+Y+C V NS
Sbjct: 615  THSGLSVN--SHMLHVDNAMLSHEGQYTCVVSNS 646



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 99/465 (21%), Positives = 184/465 (39%), Gaps = 46/465 (9%)

Query: 1227 VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            VTW +    I   T  FT++     +   +R     D   YTC  ++      L   + V
Sbjct: 121  VTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVV---DSKLYTCSAVNPAGNVSLTYNLQV 177

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            +  P+I       +   G  V L    Q  P P   W+ N   +           +    
Sbjct: 178  QAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNGLPV-----------ASDRM 226

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEI----DSSSIN 1398
            L I+ V+++D+G Y+    N+ G   +++ + +L  P+P  +   N LE+        ++
Sbjct: 227  LKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGVS 286

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS------IQN----LKTNSS 1448
            +  D     G+++  +   +++ + T E  SV+  T+ +        +QN    LK    
Sbjct: 287  LAEDGALVIGSASASHSG-DFKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRV 345

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIF 1505
                A   +    + A E    Y +    ++Q+P V      ++ +T    +++++ C  
Sbjct: 346  QHDHAGRFSCTAQNSAGEAKREYTI----EVQAPPVISGTSGVQEVTIMAGQEVDMQCRV 401

Query: 1506 GGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
             G P P V W  DG+ L      +    E                 Y+C+A N+ G    
Sbjct: 402  SGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAGTQTR 461

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + IQ  P+I  S ED +    +G   ++   +EGIP P + W K+   + +  +  +
Sbjct: 462  QFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQ--L 519

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            T  +    +R+   +   +  YT  A+N AGT+    TL++   P
Sbjct: 520  TYTQGGQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPP 564



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 58/250 (23%), Positives = 99/250 (39%), Gaps = 15/250 (6%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           T+   C  +G+P P   WF+   ++  +    +     N   L +        G +TCV 
Sbjct: 587 TLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSV---NSHMLHVDNAMLSHEGQYTCVV 643

Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
            N+AG       L ++ P   H     +             D  E  P +     + + V
Sbjct: 644 SNSAGEDKRDFHLTIQVPPVFH---RVINGAADFTLGEREGD--EEDPDSPDGMVERREV 698

Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
             G  I L C   AIP P ++W  +G ++   + + +A     H    +L+I  V+    
Sbjct: 699 LLGHSISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLA---PGH----ILQIPRVQLEDA 751

Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
           G YT  AVN  GE  +   L++        Q  E ++ +      +V L   V G+P P+
Sbjct: 752 GKYTCQAVNEAGEDKMHYDLEVLVPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPS 811

Query: 766 ITWCKNNKPV 775
           ++W K+  P+
Sbjct: 812 VSWIKDGLPL 821



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 106/483 (21%), Positives = 185/483 (38%), Gaps = 68/483 (14%)

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDE 800
            M    G  VIL  +V G+P P +TW +N +   PV A  T     +  I+ +   +V D 
Sbjct: 99   MAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDV---RVVDS 155

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
             +YT  A N  G    +  + V+     +  P         +      T+ L   V   P
Sbjct: 156  KLYTCSAVNPAGNVSLTYNLQVQAKPRIHPAP-------STLKALIGQTVVLPCVVQGEP 208

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
             P ++W  N   ++    +        I+ V        DSG Y+CVA NSAG+ +   +
Sbjct: 209  SPQVSWLHNGLPVASDRML-------KIQAV-----QHSDSGTYRCVARNSAGEDT--IQ 254

Query: 921  VTIDV-----EKVTFVK-----HLQKSYE----TEEGKTVILECQTSHT-----VSTK-- 959
            + +DV      +V + K     H+++S       E+G  VI     SH+     V+T   
Sbjct: 255  IVLDVLGSPAPQVRWFKNGLEVHMERSEHGVSLAEDGALVIGSASASHSGDFKCVATNEA 314

Query: 960  -WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI 1016
                 K  +  ++   +  +                G   C  ++   E      ++   
Sbjct: 315  GSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQA 374

Query: 1017 PEFI---RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKY-DFEKRGHI 1071
            P  I     +Q+  +       ++  ++      V W  DGE++ P  + + +F ++G +
Sbjct: 375  PPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQV 434

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVN--KGNKATF 1126
              L +++    D G Y C+  + + T        ++  P I    ++ +V    G  A  
Sbjct: 435  --LRVKSVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVL 492

Query: 1127 EIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
              E+ +G  L  + W KD   I  S  +  T  G  Q L++     +DAG Y+C   N  
Sbjct: 493  HCEV-EGIPLPTITWLKDNQPIVSSPQLTYTQGG--QSLRVAAARGEDAGAYTCRATNPA 549

Query: 1185 CTA 1187
             TA
Sbjct: 550  GTA 552



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 94/451 (20%), Positives = 168/451 (37%), Gaps = 44/451 (9%)

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE--REYRIKRGSDVT 1306
            KR L I +   D    ++C   ++    K +  + V+ PP I      +E  I  G +V 
Sbjct: 337  KRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQEVTIMAGQEVD 396

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            +       P P+ EW  + +++            K   L +K V   D G+Y+    NN 
Sbjct: 397  MQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNA 456

Query: 1367 GHADVEMNVTILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
            G    +  +TI   P     G+ + + +      +   E E     TI +        D 
Sbjct: 457  GTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLK------DN 510

Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQ-- 1480
               +S   +T TQ   Q+L+  ++    A A      + A     +Y  +++   +I+  
Sbjct: 511  QPIVSSPQLTYTQGG-QSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGD 569

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXX 1538
            S  +    +      N  + L+C+  G P+P   W++DG+ L   T      N       
Sbjct: 570  STILSFGRREEKVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSHMLHVD 629

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----------ITI-----------SN 1577
                     Y C+  N  GE +    + IQ  PV           T+           S 
Sbjct: 630  NAMLSHEGQYTCVVSNSAGEDKRDFHLTIQVPPVFHRVINGAADFTLGEREGDEEDPDSP 689

Query: 1578 EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635
            + + ++ +V  G    ++     IPPP + WY+ G +L +     +       +++I  +
Sbjct: 690  DGMVERREVLLGHSISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLAPGH---ILQIPRV 746

Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +   + KYT +A N AG   +   L+V   P
Sbjct: 747  QLEDAGKYTCQAVNEAGEDKMHYDLEVLVPP 777



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 15/179 (8%)

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXXXXXXXXXXXY 1548
            +  E   ++ L C   G P P VTW R+G+ +   TA  T                   Y
Sbjct: 99   MAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVVDSKLY 158

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
             C A N  G V  +  + +Q KP I  +   +K    +G   ++  V++G P P+V W  
Sbjct: 159  TCSAVNPAGNVSLTYNLQVQAKPRIHPAPSTLKAL--IGQTVVLPCVVQGEPSPQVSWLH 216

Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            NG  + +D+           +++I+ ++ S S  Y   A N+AG  ++++ L V   P+
Sbjct: 217  NGLPVASDR-----------MLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPA 264



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 87/370 (23%), Positives = 139/370 (37%), Gaps = 63/370 (17%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G      C+VEG P P ITW +    I  S   Q+ Y      +L +     EDAG +TC
Sbjct: 487 GFPAVLHCEVEGIPLPTITWLKDNQPIVSSP--QLTYTQGG-QSLRVAAARGEDAGAYTC 543

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            A N AG A     L +  P                         +EG     S   + +
Sbjct: 544 RATNPAGTAHRHYTLRIMVPPQ-----------------------IEGDSTILSFGRREE 580

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V     + L C     PEP   W   G+ +  + +  +++ S M      L + N    
Sbjct: 581 KVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSHM------LHVDNAMLS 634

Query: 704 QEGTYTVVAVNREGEASLPIVLKI--------------------KTGEKEPPQVIEPL-K 742
            EG YT V  N  GE      L I                    + G++E P   + + +
Sbjct: 635 HEGQYTCVVSNSAGEDKRDFHLTIQVPPVFHRVINGAADFTLGEREGDEEDPDSPDGMVE 694

Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS---ITILKPKKVKD 799
              V  G S+ LS +    P P ++W +  + +    T SDG   +   I  +   +++D
Sbjct: 695 RREVLLGHSISLSCESNAIPPPRLSWYRQGRQL----TSSDGVVLAPGHILQIPRVQLED 750

Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            G YT +A N  G  +    + V  P   + +   F+   Q++      T+ L   V+ +
Sbjct: 751 AGKYTCQAVNEAGEDKMHYDLEVLVPPVISGQTDEFM---QDVDTVVNSTVSLRCDVSGH 807

Query: 860 PVPSITWYRN 869
           P PS++W ++
Sbjct: 808 PSPSVSWIKD 817



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 78/360 (21%), Positives = 127/360 (35%), Gaps = 39/360 (10%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G   +L C +  IP P I WL   + IV    ++             L++   +    G 
Sbjct: 487 GFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQGGQS------LRVAAARGEDAGA 540

Query: 708 YTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPL--KSMIVRQGESVILSAQVVGNPRP 764
           YT  A N  G A     L+I    + E    I     +   VR   ++ LS    G P P
Sbjct: 541 YTCRATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEP 600

Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
              W K+ + +             +  +    +  EG YT    NS G  +    +T++ 
Sbjct: 601 VTQWFKDGQLLNGNTHSGLSVNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHLTIQV 660

Query: 825 PT--------------------EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
           P                     EE+ + P  +   +E+ +    +I L       P P +
Sbjct: 661 PPVFHRVINGAADFTLGEREGDEEDPDSPDGMVERREVLLGH--SISLSCESNAIPPPRL 718

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           +WYR    ++ S+ +          L I  V  E D+G Y C A N AG+      + + 
Sbjct: 719 SWYRQGRQLTSSDGVVL---APGHILQIPRVQLE-DAGKYTCQAVNEAGEDKMHYDLEVL 774

Query: 925 VEKVTF--VKHLQKSYETEEGKTVILECQTS-H-TVSTKWYHNKKEISGMDHREIIQEGR 980
           V  V         +  +T    TV L C  S H + S  W  +   +       I+++G+
Sbjct: 775 VPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLPLYSDSRHNILEDGK 834



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V  +C+V G P P + W     ++ P+ D  + + +     L ++ V P D G + C
Sbjct: 392 GQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKG-QVLRVKSVRPRDRGLYQC 450

Query: 584 VAKNAAGFASSTTELIVE-APL---SDHGSEMTV 613
           VA N AG  +    L ++ APL   S   SE+TV
Sbjct: 451 VATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTV 484



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 36/139 (25%), Positives = 59/139 (42%), Gaps = 4/139 (2%)

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            I L+C    +P P+++WYR G++L ++                       Y C A N+ G
Sbjct: 704  ISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLAPGHILQIPRVQLEDAGKYTCQAVNEAG 763

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            E +    + +   PVI+   ++  Q     V     +   + G P P V W K+G  L +
Sbjct: 764  EDKMHYDLEVLVPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLPLYS 823

Query: 1616 DKEYNITTKEKTSVIRIKE 1634
            D  +NI    K  + R+KE
Sbjct: 824  DSRHNILEDGKL-LERLKE 841



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 70/321 (21%), Positives = 128/321 (39%), Gaps = 26/321 (8%)

Query: 1082 HDE-GEYSCILRDESCTA--EVTV-VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDA 1135
            HD  G +SC  ++ +  A  E T+ V+ PP I   + +Q   +  G +   +  ++ G  
Sbjct: 347  HDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVS-GRP 405

Query: 1136 L--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----L 1189
            L  V W  DG  +  +    +    K Q L++      D G Y C   N+  T      L
Sbjct: 406  LPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAGTQTRQFRL 465

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDV 1248
            T++   +         + V     A L  E+    L  +TW K    I  + + T     
Sbjct: 466  TIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQG- 524

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEV---VEFPPKIVDY-EREYRIK 1300
              ++L +     +D   YTC   +   T      L++ V   +E    I+ +  RE +++
Sbjct: 525  -GQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVR 583

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
                +TL    + FP+P  +W  + +++    H+  S++S    L +     +  G Y  
Sbjct: 584  INGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSH--MLHVDNAMLSHEGQYTC 641

Query: 1361 RLENNCGHADVEMNVTILDKP 1381
             + N+ G    + ++TI   P
Sbjct: 642  VVSNSAGEDKRDFHLTIQVPP 662



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 5/141 (3%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITI---SNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
            Y C A +  G       + +  KP I     S   +K   +VG E ++   ++G P P V
Sbjct: 62   YICTATSAVGYTSREMHLIVNSKPRIVGADGSQVTVKMAAEVGSEVILPCEVQGSPTPLV 121

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W +NG  +     +   T   +  ++I +++   S  YT  A N AG  S+   L+V  
Sbjct: 122  TWSRNGQTIPPVTAW--FTMLPSGSLKISDVRVVDSKLYTCSAVNPAGNVSLTYNLQVQA 179

Query: 1665 KPSKPEGPVIMREISRESVTI 1685
            KP     P  ++ +  ++V +
Sbjct: 180  KPRIHPAPSTLKALIGQTVVL 200



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 55/240 (22%), Positives = 90/240 (37%), Gaps = 12/240 (5%)

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVE---EPSINFTLRLPEFILVPANTDA 1214
            K+ LKIY    D AG +SC   NS  +     T+E    P I+ T  + E + + A  + 
Sbjct: 337  KRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQE-VTIMAGQEV 395

Query: 1215 YLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
             +   +    L  V W     V+       +    K + L ++     D+  Y CV  + 
Sbjct: 396  DMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNN 455

Query: 1274 KSTTKLKVEV-VEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
              T   +  + ++  P I D   + E  +  G    L  + +  P P   W+ +++ I  
Sbjct: 456  AGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPI-- 513

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390
                + +      SL +      DAG Y  R  N  G A     + I+  P   G   IL
Sbjct: 514  VSSPQLTYTQGGQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGDSTIL 573



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V   C+V+G P P +TW R    I P      ++      +L I +V   D+  +TC
Sbjct: 104 GSEVILPCEVQGSPTPLVTWSRNGQTIPP---VTAWFTMLPSGSLKISDVRVVDSKLYTC 160

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTV 613
            A N AG  S T  L V+A    H +  T+
Sbjct: 161 SAVNPAGNVSLTYNLQVQAKPRIHPAPSTL 190


>UniRef50_UPI0000E46511 Cluster: PREDICTED: similar to Fibronectin
            type-III domain-containing protein 3a; n=3;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            Fibronectin type-III domain-containing protein 3a -
            Strongylocentrotus purpuratus
          Length = 1345

 Score =  114 bits (275), Expect = 2e-23
 Identities = 120/451 (26%), Positives = 182/451 (40%), Gaps = 42/451 (9%)

Query: 1616 DKEYNITTKEKTSVIRIK-ELKRSHSSKYTIEAS---------NTAGTS---SVEVTLKV 1662
            DK+Y IT  + +++ R + +   SH S + + +S         N  G S   S+     +
Sbjct: 654  DKQYKITKLQPSTLYRFRLQAINSHGSSFYLYSSSINFDLCAFNEEGNSRWSSIVAFRTM 713

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722
             D P  P  P +  +    S  I W PP D GG E+T Y +EK E  N  +   +   R 
Sbjct: 714  PDAPRAPSKPSLKGKPHSTSFKIMWDPPRDCGGSEITSYQLEKAEVRNGPF---SPAYRG 770

Query: 1723 VE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            +E  +    L   C Y  RV   +  G S    SE   I T   VP              
Sbjct: 771  MEREHQFDNLKPGCTYYLRVSCTSKGGASPC--SEVFSITTLPIVPGQSHTPRVHGKPKA 828

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRI 1839
             SV + W   + NGG+PI ++ VE+                     +  L    TY FR+
Sbjct: 829  TSVNLRWGMPDYNGGAPITEFSVEMTAADNVTSEVHRATADITECTVNSLLPGRTYDFRL 888

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             + N+IG   PY+   +++ G    PP  P     S  T+  V L W +P  N G+ IT 
Sbjct: 889  RSCNKIGYG-PYSEPLRVSTG--AGPPDAPTELTASCVTTSVVLLSWQKPCFN-GADITE 944

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959
            Y +E  +  G   T  +   GS     I  ++       R+ A N  G   P  S    +
Sbjct: 945  YRVEKASENG---TFSLAYSGSATTCEIRGLQPATYYYMRVQALNAAGHG-PFSS----V 996

Query: 1960 EKHATVPSPPTAPLEIRMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
                T+PS P A   +R+V   S+ ++  W  P  D G+ ++ YN+ I +          
Sbjct: 997  ATCQTLPSSPEAVPSLRVVSSTSDSLLIQWTEPS-DCGSEIIAYNLDIGEGQPIF----- 1050

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             V+ N  ++ +  L  +  Y IR+ A N IG
Sbjct: 1051 -VEGNVTQYCVDQLEPDTKYRIRVQALNSIG 1080



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 62/300 (20%), Positives = 121/300 (40%), Gaps = 18/300 (6%)

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671
            K   +  +++      +   I+ L+ +      ++A N AG             PS PE 
Sbjct: 949  KASENGTFSLAYSGSATTCEIRGLQPATYYYMRVQALNAAGHGPFSSVATCQTLPSSPEA 1008

Query: 1672 PVIMREISR--ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729
               +R +S   +S+ I+W  P D G  E+  Y ++  E       +   V+ +V  YC+ 
Sbjct: 1009 VPSLRVVSSTSDSLLIQWTEPSDCGS-EIIAYNLDIGEG------QPIFVEGNVTQYCVD 1061

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789
            +L  + +Y  RV A N +G          + +    +P             ++S+ + W 
Sbjct: 1062 QLEPDTKYRIRVQALNSIGEGPYSAVLKAITRALPPIPPRLECVYYS----HQSLKLKWG 1117

Query: 1790 PSEKNGG-SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
               +  G S  +++ +E++ +  ++           ++ +LS +T+Y+FRI A NE GT 
Sbjct: 1118 DQNRIAGDSKSVNFTLEMEDKRGRFVVVYSGINLNQKVTRLSESTSYKFRILASNEAGTG 1177

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
             PY+ D       T  PP   +     E    S  + W E   +    + +Y  +++  +
Sbjct: 1178 -PYSED--FVFATTKAPPVTLK-APTMEVDQDSCQISWAEAILHQQEDLMHYQCQYQRTR 1233



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 1/105 (0%)

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
            E N   + +    T+ D P  P KP++  +  S+S  I WD P + G S I  Y +E  E
Sbjct: 699  EGNSRWSSIVAFRTMPDAPRAPSKPSLKGKPHSTSFKIMWDPPRDCGGSEITSYQLEKAE 758

Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
            +    +       + +    NLK   +Y  R    ++   S  SE
Sbjct: 759  VRNGPFSPAYRGMEREHQFDNLKPGCTYYLRVSCTSKGGASPCSE 803



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 10/110 (9%)

Query: 1355 AGIYKLRLE--NNCGHADVEMNVTILDKPSPPGKPNILEIDSS---SINICWDEPENTGN 1409
            A  Y +R++  N  GH       T    PS P     L + SS   S+ I W EP + G+
Sbjct: 975  ATYYYMRVQALNAAGHGPFSSVATCQTLPSSPEAVPSLRVVSSTSDSLLIQWTEPSDCGS 1034

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
              I Y +    +I   + I V+    TQ  +  L+ ++ YR R  A+N +
Sbjct: 1035 EIIAYNL----DIGEGQPIFVEG-NVTQYCVDQLEPDTKYRIRVQALNSI 1079


>UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precursor;
            n=7; Clupeocephala|Rep: Neural cell adhesion molecule L1
            precursor - Fugu rubripes (Japanese pufferfish) (Takifugu
            rubripes)
          Length = 1277

 Score =  114 bits (275), Expect = 2e-23
 Identities = 154/710 (21%), Positives = 271/710 (38%), Gaps = 62/710 (8%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
            PP    + + +TV     + +    + NP P+  W ++ E   PS         E    V
Sbjct: 50   PPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSV 109

Query: 892  ITNVDSEIDS-----GDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
               + + +D+     G Y C ASN  G + S+ A + ID   V   K  + + + E G +
Sbjct: 110  FYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQ-QKEKKVTEKAEAGHS 168

Query: 946  VILEC---QTSHTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXXD-------- 993
            + L C   Q+S      W  N+ + I   D   + ++G             +        
Sbjct: 169  IALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQY 228

Query: 994  VGVIKCIVKDQETSTM----LVVKETIPEFIRKL---QDFEVKEKDVAILEVEINS-ETA 1045
            +     + K+  T T+    LV +   P+ +R       +         LE  +    T 
Sbjct: 229  LATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTP 288

Query: 1046 DVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVT 1101
             V W R DGE+ + + +K  F++R     L   N S  D GEY C    ++  +      
Sbjct: 289  KVSWLRKDGEMSESRISKDMFDRR-----LQFTNISESDGGEYQCTAENVQGRTFHTYTV 343

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKK 1160
             VE  P       +Q    G     + +        + W  +G  +  ++        + 
Sbjct: 344  TVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTES 403

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
              L + D    D   Y C+  N   T +         + + LP  IL   N + Y  VE 
Sbjct: 404  GSLILKDVIFGDTAIYQCQASNKHGTILANTNV----YVIELPPQILTE-NGNTYTFVEG 458

Query: 1221 PDETLDVTWY---KKKSVIEDTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLD 1272
                L+   +   K K   E +    L++D +   L      I   + DD+  YTC++  
Sbjct: 459  QKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNGGLEIANVSHDDEGIYTCLVQG 518

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ---PNDEWIVNSKIIK 1329
            +  +   +VEV+     I+   +  R++ G        Y   P+   P  +W  N + I 
Sbjct: 519  SNISVNAEVEVLN-RTVILSPPQALRLQPGKTAIFTCLYVTDPKLSSPLLQWRKNDQKIF 577

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
            +  H+          L I  VE  D G+Y  ++       +    +T+ D+P PP    +
Sbjct: 578  E-SHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRPDPPVHLQV 636

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITKTQTSIQ-NLKTN 1446
                   + + W  P +  NS I+ YVVE+++ D  E  W  +K +   +  +   L   
Sbjct: 637  TNAKHRVVTLNW-TPGDDNNSPILEYVVEFEDQDMKENGWEELKRVAADKKHVNLPLWPY 695

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
             SYRFR  A+N+   SD S+ ++ YK   +    +P   + +++ +T+P+
Sbjct: 696  MSYRFRVIAINDQGKSDPSKLSDLYKTPADAPDSNP---EDVRSESTDPD 742



 Score =  101 bits (241), Expect = 3e-19
 Identities = 143/580 (24%), Positives = 226/580 (38%), Gaps = 50/580 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP--DENISVAIESDMH 689
            IPP  + +P++  V    D+++ C     P P   W   GEE  P  D  + V  E+   
Sbjct: 49   IPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSS 108

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            ++ ++    +  K  +G Y   A N  G A S   VL I   +  P Q  E   +     
Sbjct: 109  VFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMI---DAPPVQQKEKKVTEKAEA 165

Query: 749  GESVILSAQ-VVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVY 803
            G S+ LS      + +P I W  N      L  +     DG+ +   +L      D    
Sbjct: 166  GHSIALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCN 225

Query: 804  TLKAENSEGIAETSAVITVEEP--TEENAEPPLFINRFQEITVKE-KG-TIKLVARVTRN 859
                     +A+    +TV        N  P +        T    +G T++L   V   
Sbjct: 226  IQYLATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGL 285

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P ++W R +  +S S      FD     L  TN+ SE D G+Y+C A N  G++ H  
Sbjct: 286  PTPKVSWLRKDGEMSESRISKDMFDR---RLQFTNI-SESDGGEYQCTAENVQGRTFH-- 339

Query: 920  RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEIS--GMDHREI 975
              T+ VE   +  +   S     G+TV L+CQ     S    W  N   +S   ++ R  
Sbjct: 340  TYTVTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRS 399

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKL-QDFEVKE 1030
            + E              D  + +C   ++      +T + V E  P+ + +    +   E
Sbjct: 400  LTE--SGSLILKDVIFGDTAIYQCQASNKHGTILANTNVYVIELPPQILTENGNTYTFVE 457

Query: 1031 KDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
               A+LE E   S    V WE     +     + +    G    L I N S  DEG Y+C
Sbjct: 458  GQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNG---GLEIANVSHDDEGIYTC 514

Query: 1090 ILRDE--SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD 1142
            +++    S  AEV     TV+  PP+ + RLQ  K        +  +      L++W K+
Sbjct: 515  LVQGSNISVNAEVEVLNRTVILSPPQAL-RLQPGKTAIFT-CLYVTDPKLSSPLLQWRKN 572

Query: 1143 GSEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180
              +I F +H   + T DG    L I + +  D G Y+C++
Sbjct: 573  DQKI-FESHSDKKYTFDG--PGLIISNVEPGDEGVYTCQI 609



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 9/174 (5%)

Query: 1497 EDIELTCIFGGVPQPKVTWYR-DGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            + +EL CI  G+P PKV+W R DG+  + + +K  ++ R               Y+C A 
Sbjct: 274  QTLELECIVQGLPTPKVSWLRKDGEMSESRISKDMFDRR--LQFTNISESDGGEYQCTAE 331

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N  G    +  V ++  P  T  N  + Q +  G+   +    +GIP P + W  NG  L
Sbjct: 332  NVQGRTFHTYTVTVEASPYWT--NAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPL 389

Query: 1614 E-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                 E   +  E  S+I +K++    ++ Y  +ASN  GT      + V + P
Sbjct: 390  SATSLEPRRSLTESGSLI-LKDVIFGDTAIYQCQASNKHGTILANTNVYVIELP 442



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
           H   G T++ EC V+G P P+++W R+   +  S+  +  +D      L    +   D G
Sbjct: 269 HALRGQTLELECIVQGLPTPKVSWLRKDGEMSESRISKDMFD----RRLQFTNISESDGG 324

Query: 580 TFTCVAKNAAGFASSTTELIVEA 602
            + C A+N  G    T  + VEA
Sbjct: 325 EYQCTAENVQGRTFHTYTVTVEA 347



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 10/171 (5%)

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKC 1550
            P E ++L C   G+P P +TW  +G  L       + +                   Y+C
Sbjct: 362  PGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQC 421

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             A N HG +  +  V + + P   ++          G + L+     G P P+V W  + 
Sbjct: 422  QASNKHGTILANTNVYVIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSS 481

Query: 1611 -NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT--IEASNTAGTSSVEV 1658
             + L  D   N+ T      + I  +       YT  ++ SN +  + VEV
Sbjct: 482  ISLLLADPRVNLLT---NGGLEIANVSHDDEGIYTCLVQGSNISVNAEVEV 529



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 46/203 (22%), Positives = 85/203 (41%), Gaps = 24/203 (11%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIES 686
           ++E  P   ++        EG   LLEC     P+P + W       ++ D  +++    
Sbjct: 438 VIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNG 497

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
                   L+I NV    EG YT +        +  + +  +T    PPQ +       +
Sbjct: 498 G-------LEIANVSHDDEGIYTCLVQGSNISVNAEVEVLNRTVILSPPQALR------L 544

Query: 747 RQGESVILSAQVVGNPR---PTITWCKNNKPV-KALPTKS---DGDTHSITILKPKKVKD 799
           + G++ I +   V +P+   P + W KN++ + ++   K    DG    I+ ++P    D
Sbjct: 545 QPGKTAIFTCLYVTDPKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEP---GD 601

Query: 800 EGVYTLKAENSEGIAETSAVITV 822
           EGVYT +      + E S+ +T+
Sbjct: 602 EGVYTCQIITKLDMVEASSTLTL 624



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G TV+ +CQ +G P P ITW     +   +   +         +L++++V   D   + C
Sbjct: 363 GETVKLDCQADGIPSPTITW-TVNGVPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQC 421

Query: 584 VAKNAAG-FASSTTELIVEAP---LSDHGSEMT 612
            A N  G   ++T   ++E P   L+++G+  T
Sbjct: 422 QASNKHGTILANTNVYVIELPPQILTENGNTYT 454



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 7/107 (6%)

Query: 1852 TSDDKITIGKTLT---PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KT 1906
            T  D +    TLT    P  P +  V+ +  R VTL WT P  +  SPI  Y++EF  + 
Sbjct: 611  TKLDMVEASSTLTLCDRPDPPVHLQVTNAKHRVVTLNWT-PGDDNNSPILEYVVEFEDQD 669

Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            +K   W ++  V     +H    +       FR+ A N  G S P++
Sbjct: 670  MKENGWEELKRVAAD-KKHVNLPLWPYMSYRFRVIAINDQGKSDPSK 715


>UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein; n=3;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 1495

 Score =  113 bits (273), Expect = 4e-23
 Identities = 93/400 (23%), Positives = 169/400 (42%), Gaps = 18/400 (4%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727
            P   + + E ++  V + WKPP+  G  E   Y +EK     + W +V   +      + 
Sbjct: 556  PPTDLAVTEATKSYVVLSWKPPVQRGH-EGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFA 614

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L E+  Y FRV + N  G  E + E+    +   LD+PS           D+ SV +
Sbjct: 615  LFDLAEDKSYTFRVRSCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDS-SVVV 673

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQ--FRIYARN 1843
             W  S++     ++ Y +E+  +G   W           R     +N T +  FR+ A N
Sbjct: 674  CWGASKE--VKDLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVN 731

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
              G S      +   +  ++  PS P      E     + + W  P   GG+ I  Y ++
Sbjct: 732  AAGYSGSSAESEACLVKASIAVPSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLD 791

Query: 1904 FKTVKG---KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSV 1957
            ++TVK      W ++     +   + + ++KE +   F++ A N  G+   S+PT     
Sbjct: 792  YRTVKDGVTSKWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLEC 851

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
            + E    VP PP   L ++ V  + ++  W  P ++G +P+ GY +  ++     W  V 
Sbjct: 852  K-EWTVAVPGPPHG-LRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKE-ENGRWRCVQ 908

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            +         +  L E  +Y +RI+A+N  G+  P ++ +
Sbjct: 909  ERSTKHTYMKVSGLQEGISYRLRIHAKNLAGVGVPSKATD 948



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 88/327 (26%), Positives = 139/327 (42%), Gaps = 18/327 (5%)

Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            RS +S    E S   G ++V   L   D PS P GPVI    +  SV + W    +    
Sbjct: 629  RSCNSAGVGEPSEETGATTVGDRL---DLPSAP-GPVIPIRNTDSSVVVCWGASKEVK-- 682

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALES 1755
            +L  Y IE     +  W    +       +    LN   +  FRV A N  G+S  + ES
Sbjct: 683  DLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAES 742

Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEG--K 1811
            E  ++K ++ VPS          + +  V I W    K GG+ I  Y ++ +  ++G   
Sbjct: 743  EACLVKASIAVPSPPTGVTTLERLRDYMV-IGWQAPAKTGGADIRGYYLDYRTVKDGVTS 801

Query: 1812 KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQ 1868
            KW          +  ++  L  N  YQF++ A N+ G S        +   + T+  P  
Sbjct: 802  KWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGP 861

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-I 1927
            P    V E    S+ + W  P  NG SP+T Y ++FK   G+ W + V    + H +  +
Sbjct: 862  PHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKEENGR-W-RCVQERSTKHTYMKV 919

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTES 1954
              ++E      RI A+N  GV +P+++
Sbjct: 920  SGLQEGISYRLRIHAKNLAGVGVPSKA 946



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 74/295 (25%), Positives = 118/295 (40%), Gaps = 18/295 (6%)

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIY 1840
            V ++W P  + G   ++ Y  +       W+         +    +  L+ + +Y FR+ 
Sbjct: 570  VVLSWKPPVQRGHEGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVR 629

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            + N  G   P       T+G  L  PS P   +   +T  SV + W    S     +  Y
Sbjct: 630  SCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDSSVVVCWGA--SKEVKDLVGY 687

Query: 1901 IIEFKTVKGKS-WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVR 1958
             IE  TV G   W                 +   D+  FR+ A N  G S    ES++  
Sbjct: 688  YIEV-TVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACL 746

Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI---AIRDVTKTMWME 2015
            ++    VPSPPT    +  +   +V+  W  P   GGA + GY +    ++D   + W E
Sbjct: 747  VKASIAVPSPPTGVTTLERLRDYMVI-GWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHE 805

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE------PLESDEPFKVIPG 2064
            +    V +  + + DL EN  Y  ++ A N+ G+SE      PLE  E    +PG
Sbjct: 806  LNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPG 860



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 7/165 (4%)

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            PE++WY+NG  L + K  ++    + + + +  L +     YT+  +  +G  +    + 
Sbjct: 355  PEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVF 414

Query: 1662 VYDKPSKPEG----PVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            V D   + EG    P+ +R  + +++ V + WK P  +G   +T Y I++ E  N+ W +
Sbjct: 415  VRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQ 474

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759
              D       + +  L E   YMFRV A N  G S  +  S+P+V
Sbjct: 475  CNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVV 519



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            PS P G   +  + R+ + I W+ P   GG ++  Y ++     +    K  +++    T
Sbjct: 754  PSPPTGVTTLERL-RDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVT 812

Query: 1726 ---YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
               Y +  L EN  Y F+V A N  G SEA + + P+  K                 +  
Sbjct: 813  SSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGPPHGLRVQEVRK 872

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRI 1839
            +S+ + W P   NG SP+  Y V+ K+E  +W+            ++  L    +Y+ RI
Sbjct: 873  DSMVVLWEPPTFNGRSPVTGYYVDFKEENGRWRCVQERSTKHTYMKVSGLQEGISYRLRI 932

Query: 1840 YARNEIGTSLPYTSDDKI 1857
            +A+N  G  +P  + D I
Sbjct: 933  HAKNLAGVGVPSKATDAI 950



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 76/294 (25%), Positives = 127/294 (43%), Gaps = 36/294 (12%)

Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV----VAVNREGEASLPI 723
           L + +E V +E +   +  ++    S  K+  VKK +E +       +A++++       
Sbjct: 131 LMETQEEVKEEGVGYVVMRNLFARESGFKMRTVKKTRETSMRESAERMALSQKLHEKEQF 190

Query: 724 VLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALP- 779
             K+       PP+ I   +   V +G+SV L   V G P+P + W KNN  +  KA P 
Sbjct: 191 QKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKNNVLIDAKARPE 250

Query: 780 ---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPP- 833
              T+S  + HS+ I K     D   Y + A N +G +   A + ++  +  EE  E P 
Sbjct: 251 KYFTESQYNMHSLEI-KNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPH 309

Query: 834 ------------LFINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPS 876
                         I++F     +E  T+ L   V   P      P I WYRN   +S S
Sbjct: 310 GYSPEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSS 369

Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEK 927
           + +  ++ GE   L + +++ E D G Y    +  +G  +H A V +   DVE+
Sbjct: 370 KWVHMHWSGEKATLTLVHLNKE-DEGLYTLRVNTKSGFDTHSAYVFVRDADVEE 422



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 28/228 (12%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F  KP+ Q V EG  + L C +   P+P +AW +K   ++  +       ++     
Sbjct: 202 PPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAW-YKNNVLIDAKARPEKYFTESQYNM 260

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKE--------PPQ------ 736
             L+I N        Y + A+N +GE+S   P+++K    E+E         P+      
Sbjct: 261 HSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPHGYSPEYGVTFN 320

Query: 737 --VIEPLKSMIVRQGESVILSAQVVGNP-----RPTITWCKNNKPV---KALPTKSDGDT 786
             +I+       R+GE++ L   V+  P     +P I W +N   +   K +     G+ 
Sbjct: 321 TTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEK 380

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
            ++T++   K +DEG+YTL+     G    SA + V +   E    P+
Sbjct: 381 ATLTLVHLNK-EDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEGVPV 427



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 53/214 (24%), Positives = 85/214 (39%), Gaps = 8/214 (3%)

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTP--PSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
            AR   G S P+T   K T         P  P +  V+E+T   V L W  P   G   + 
Sbjct: 527  ARLRAGPSAPWTGVIKFTEEDPTVGVIPGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVM 586

Query: 1899 NYIIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQS 1956
             Y +E   V   +W ++ T +        + ++ E     FR+ + N+ GV  P+ E+ +
Sbjct: 587  -YYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSEETGA 645

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016
              +     +PS P   + IR   S++V+  WG  +      L+GY I +      +W   
Sbjct: 646  TTVGDRLDLPSAPGPVIPIRNTDSSVVV-CWGASK--EVKDLVGYYIEVTVDGSGVWAPC 702

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
                V   +F    L+       R+ A N  G S
Sbjct: 703  NNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYS 736



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%)

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTS 1986
            ++ ++DE ++ +      G    +    VR +        P APL++R   +N   V+ +
Sbjct: 387  HLNKEDEGLYTLRVNTKSGFDTHSAYVFVR-DADVEEEGVPVAPLDVRCHDANKDYVVVT 445

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P  +G + + GY I   +V    W +     V   +F +  L E  +YM R+ A N 
Sbjct: 446  WKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARFPVTGLIEGRSYMFRVRALNN 505

Query: 2047 IGLSEPLESDEP 2058
             G+S P    +P
Sbjct: 506  AGVSRPSRVSDP 517



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 45/238 (18%), Positives = 97/238 (40%), Gaps = 20/238 (8%)

Query: 488 LNEKIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           L++K+ +   F+K  + +  +  P F+ K R +   +G +V   C V G+P+P++ W++ 
Sbjct: 180 LSQKLHEKEQFQKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKN 239

Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
             +I      + Y+ +   N+ +L I+     D   +   A N  G +S+   +I++   
Sbjct: 240 NVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFK 299

Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP--- 661
            +                     I++    +F +        EG  + L C ++  P   
Sbjct: 300 EEEELVERPHGYSPEYGVTFNTTIIDKFDVSFGR--------EGETMSLGCTVIVYPTVK 351

Query: 662 --EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             +P+I W   G  +   + + +    +     + L + ++ K  EG YT+    + G
Sbjct: 352 RYQPEIVWYRNGVALSSSKWVHMHWSGEK----ATLTLVHLNKEDEGLYTLRVNTKSG 405



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 60/283 (21%), Positives = 99/283 (34%), Gaps = 40/283 (14%)

Query: 1227 VTWYKKKSVIEDT---EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            V WYK   +I+     EK+   S     +L I+ CT  D  EY    L+ K  +     V
Sbjct: 234  VAWYKNNVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPV 293

Query: 1284 V--------EFPPKIVDYEREYRI---------------KRGSDVTLLVDYQAFP----- 1315
            +        E   +   Y  EY +               + G  ++L      +P     
Sbjct: 294  IIKRFKEEEELVERPHGYSPEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRY 353

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
            QP   W  N   +   K        + A+LT+  +   D G+Y LR+    G       V
Sbjct: 354  QPEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYV 413

Query: 1376 TILDK-------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
             + D        P  P      + +   + + W +P   G+S I  Y ++  E+    W 
Sbjct: 414  FVRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWT 473

Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
               +  +   +  +  L    SY FR  A+N   +S  S  ++
Sbjct: 474  QCNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSD 516



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 55/218 (25%), Positives = 84/218 (38%), Gaps = 31/218 (14%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P +    ++    V + W +P   G S IT Y I+   V    WT+           
Sbjct: 426  PVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARF 485

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE----------SQSVRL---------------E 1960
             +  + E    +FR+ A N  GVS P+           S   RL               E
Sbjct: 486  PVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVVAMDPSDRARLRAGPSAPWTGVIKFTE 545

Query: 1961 KHATV---PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
            +  TV   P PPT  L +     + V+ SW  P   G   ++ Y +    V    W  V 
Sbjct: 546  EDPTVGVIPGPPT-DLAVTEATKSYVVLSWKPPVQRGHEGVM-YYVEKCLVGTDAWQRVN 603

Query: 2018 K-VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
              + V + +F + DL+E+ +Y  R+ + N  G+ EP E
Sbjct: 604  TGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSE 641



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID---TTEW--ISVKNITK 1435
            PSPP     LE     + I W  P  TG + I  Y ++Y+ +    T++W  +++K +T 
Sbjct: 754  PSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVTS 813

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
            +   + +LK N  Y+F+  A N+  IS+AS  T
Sbjct: 814  SPYKVTDLKENEFYQFQVRAFNQAGISEASIPT 846



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 69/280 (24%), Positives = 109/280 (38%), Gaps = 40/280 (14%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC---DLDDAGEYSCEVGNSKCTAILTVEE 1193
            + WFKDG EI+  +     I GK  ++  +D       DAG Y  ++ + +      +  
Sbjct: 1206 IAWFKDGIEIEEDDEDAKKI-GKSDEVLTFDIGKISKKDAGVYEVKLKDERGKDKTLLNL 1264

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPD-------------ETLDVTWYKKKSVIEDTE 1240
                +   L E   V AN+   L V   +             E L V W  K+S I  ++
Sbjct: 1265 TDAGYQAVLNEVFRVIANSSTELKVMSTEHGIILYSFVVHYLEDLRVGWLHKESKISHSD 1324

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---------EFP---- 1287
            +       ++  L I + TE D+ +Y   + D K + K  +++          EF     
Sbjct: 1325 RVQCGVTGEQLWLKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKA 1384

Query: 1288 PKIVDYERE---------YRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPS 1337
              I +  R            I+ G  + L  +    P P   WI N K ++    HT   
Sbjct: 1385 AAIAERNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKY 1444

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              SK AS+TI  V  TD+G Y L ++N  G    E  V++
Sbjct: 1445 EHSKFASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSV 1484



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 69/341 (20%), Positives = 131/341 (38%), Gaps = 47/341 (13%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGY-PRPQITWFRQ-TAIIKPSQDFQMYYDDDNVAT 567
            P FVE L  + TP+   V  +C+V    P  +I WF+    I +  +D +     D V T
Sbjct: 1175 PHFVEYLSFEVTPE-CDVHLKCKVGNIKPATEIAWFKDGIEIEEDDEDAKKIGKSDEVLT 1233

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
              I ++  +DAG +    K+                  + G + T+             +
Sbjct: 1234 FDIGKISKKDAGVYEVKLKD------------------ERGKDKTLLNLTDAGYQAVLNE 1275

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +   I  + S + K    + G  IL    +  + +  + WL K  +I   + +   +  +
Sbjct: 1276 VFRVIANS-STELKVMSTEHGI-ILYSFVVHYLEDLRVGWLHKESKISHSDRVQCGVTGE 1333

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL-------------KIKTG---E 731
                   LKI    +  +G Y +   + +G     + L             ++K     E
Sbjct: 1334 QLW----LKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKAAAIAE 1389

Query: 732  KEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787
            +   +V+  L  ++ +++G+S+ L+  V G+P P ++W KN KP+   +    K +    
Sbjct: 1390 RNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKF 1449

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            +   +      D G Y L  +N  G       ++V  P +E
Sbjct: 1450 ASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSVYIPEDE 1490



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 5/100 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQT 1438
            P PP    + E+   S+ + W+ P   G S +  Y V+++E +   W  +  ++   T  
Sbjct: 859  PGPPHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKE-ENGRWRCVQERSTKHTYM 917

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             +  L+   SYR R +A N   +   S+ T+   ++ ET+
Sbjct: 918  KVSGLQEGISYRLRIHAKNLAGVGVPSKATD--AILAETR 955



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 67/295 (22%), Positives = 125/295 (42%), Gaps = 48/295 (16%)

Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184
            FE    K D+   W K+      S+ + +   G K +    D  LDD G YSC V N+  
Sbjct: 975  FECSDLKEDSQFVWSKNYEAFTDSSRLTIQTTGGKSRAIFNDPSLDDLGIYSCVVTNTDG 1034

Query: 1185 CTAILTVEEPSINFTLRLP---EFILVPANTDAYLTVEIPDE--------------TLDV 1227
             +A  T+ E  +   L +    +F ++P  ++  + +E+ ++               L V
Sbjct: 1035 VSASYTLTEEGLKRLLDISHDHQFPIIPFKSE--MAIELQEKGRVRFWAEVGKFTSNLQV 1092

Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE----DDQCEYTCVLLDAKSTTKLKVEV 1283
             +    +VI + +K+T+  +  K T II    +     D+  +T  L+D K+T +  + +
Sbjct: 1093 EYVFNDNVIHEGKKYTM--NFNKSTGIIEMFMDLLEVTDEGTFTFNLVDGKATGRTSLVL 1150

Query: 1284 V--EFP--PKIVDYER-EYRIKRGSDVTLLVDYQAFPQ-------------PNDE--WIV 1323
            +  EF    K  ++ER E+  ++G      + ++  P+             P  E  W  
Sbjct: 1151 IGEEFAELQKKSEFERAEWVRRQGPHFVEYLSFEVTPECDVHLKCKVGNIKPATEIAWFK 1210

Query: 1324 NSKIIKKCKHTKPSIDSKSASLT--IKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
            +   I++       I      LT  I K+   DAG+Y+++L++  G     +N+T
Sbjct: 1211 DGIEIEEDDEDAKKIGKSDEVLTFDIGKISKKDAGVYEVKLKDERGKDKTLLNLT 1265



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  + G P PEV W KN   L  D+ + +  +  K + I I  +  + S KY +   N 
Sbjct: 1413 LTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDSGKYALLVKNK 1472

Query: 1651 AGTSSVEVTLKVY 1663
             GT + E T+ VY
Sbjct: 1473 YGTEAAEFTVSVY 1485



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P PP    + E   S + + W  P   G+  ++YY VE   + T  W  V     +   +
Sbjct: 554  PGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVMYY-VEKCLVGTDAWQRVNTGIPVKSPR 612

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468
             ++ +L  + SY FR  + N   + + SE T
Sbjct: 613  FALFDLAEDKSYTFRVRSCNSAGVGEPSEET 643



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 7/102 (6%)

Query: 513 VEKLRPKHTPDGSTVQFECQVEGYP-----RPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567
           ++K       +G T+   C V  YP     +P+I W+R    +  S+   M++  +  AT
Sbjct: 324 IDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEK-AT 382

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHG 608
           L +  +  ED G +T      +GF + +  + V +A + + G
Sbjct: 383 LTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEG 424



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +T++E  ++ L   V  +P P ++W +N + +   E  T  ++      +     +  DS
Sbjct: 1403 VTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDS 1462

Query: 902  GDYKCVASNSAGKSSHGARVTIDV 925
            G Y  +  N  G  +  A  T+ V
Sbjct: 1463 GKYALLVKNKYG--TEAAEFTVSV 1484



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 4/107 (3%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435
            LD PS PG    +    SS+ +CW   +      ++ Y +E     +  W    N  +  
Sbjct: 652  LDLPSAPGPVIPIRNTDSSVVVCWGASKEV--KDLVGYYIEVTVDGSGVWAPCNNKPVKG 709

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
            T+     L       FR  AVN    S +S  +E   V     + SP
Sbjct: 710  TRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACLVKASIAVPSP 756


>UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, member
            10; n=3; Xenopus tropicalis|Rep: immunoglobulin
            superfamily, member 10 - Xenopus tropicalis
          Length = 2566

 Score =  113 bits (273), Expect = 4e-23
 Identities = 200/925 (21%), Positives = 355/925 (38%), Gaps = 84/925 (9%)

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGT 707
            SD  + C     P P I W          +   V   + M ++ +  L I +V     G 
Sbjct: 1607 SDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRV---NKMEVFMNGTLSIPSVGIQDGGQ 1663

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766
            Y  VA N+ G   L + L + T    PP++++   + + V  G SV ++ Q  G+P PTI
Sbjct: 1664 YLCVANNQLGSDRLLVTLSVIT---YPPRILQGRSREITVHSGNSVNVNCQAEGSPFPTI 1720

Query: 767  TWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            TW   N+ +    + S+           I+K   V D G+Y   A N  G  E +  + +
Sbjct: 1721 TWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAG--EDTFTVRI 1778

Query: 823  EEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR-NNEIISPSETIT 880
                +  A PP+ +   ++  +   G  +K+      NP P++ W   +   I P + + 
Sbjct: 1779 ----QVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVN 1834

Query: 881  QN-FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ---K 936
               F   N  L I NV S  D G+Y+C+A++S G       + ++ +  TF K      K
Sbjct: 1835 AKLFLFSNGTLYIRNVAS-TDRGNYECIATSSTGSERRVVNLIVE-QSDTFPKITDASPK 1892

Query: 937  SYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXXXXXXXXXX 992
            + E   G  ++L C  +     +  W    K +    HR    IQ               
Sbjct: 1893 ATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDK 1952

Query: 993  DVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVK---EKDVAILEVEINSETAD 1046
            D G   C+ +++    ++++K ++   P  I + Q    +    KD  +      S   D
Sbjct: 1953 DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQVPYGKDFKVDCKASGSPLPD 2012

Query: 1047 VVWE-RDGEIIKPKKNKYDF--EKRGHI----RKLYIRNTSVHDEGEYSCI----LRDES 1095
            + W   DG +I       D    KR +I      LY+    + +EG+Y+C     L  + 
Sbjct: 2013 ISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLGRDE 2072

Query: 1096 CTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQ 1153
                +TVV   P I   ++ +     G     + E   +    + W    S++   +H +
Sbjct: 2073 MKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIAISHDR 2132

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVE----EPSINFTLRLPEFIL 1207
              +  +   L +    L DAGEY C   N     T +L +E     P IN        I 
Sbjct: 2133 YLLH-ENGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYSNKSIIK 2191

Query: 1208 VPANTDAYLTVEIPDE---TLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
              A   +   ++   E    L V W    ++ +      + I   +  TL IR     D 
Sbjct: 2192 DTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRPSDT 2251

Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEF--PPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPN 1318
             E+TCV  +   +S   +++EV+E    P   +   E  I + S + +L  + +  P P 
Sbjct: 2252 AEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPE 2311

Query: 1319 DEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
              W++   ++ +     +K    S + +  I      DAG Y+    N  G+ +  + + 
Sbjct: 2312 IIWLLPNGTRFLNGPSISKYHAGS-NGTFIIYSPTKDDAGKYRCAARNKVGYIEKLIILE 2370

Query: 1377 ILDKPS----PPGKPNILEIDSSSINICWDEPENTGNSTII--YYVVEYQEIDTTEWISV 1430
            +  KP+    P G    +  ++ S++   D       + I+   Y +E  ++     +  
Sbjct: 2371 VGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKLLE 2430

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
                  Q +  + + N   + + YA       + + T     V    +I      KP + 
Sbjct: 2431 NGTLVIQETALHDRGNYQCKAKNYA------GETAITVTVVVVAYPPRI----TNKPPQT 2480

Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTW 1515
            I T     + L C+  G+P+P + W
Sbjct: 2481 IHTRAGSAVRLNCMAIGIPKPDIFW 2505



 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 163/792 (20%), Positives = 300/792 (37%), Gaps = 68/792 (8%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVAIES 686
            ++   P    +K +      G ++ + C     P+P + W+ F G +I P + ++  +  
Sbjct: 1780 VIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFL 1839

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
              +     L I NV     G Y  +A +  G     + L ++  +  P       K+  +
Sbjct: 1840 FSN---GTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPKATEM 1896

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802
              G+ ++L+    G P+P I W   +K V      + ++     +    +     KD G 
Sbjct: 1897 NFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDKDAGD 1956

Query: 803  YTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            Y   A N  G       ++V  +P +   + PL         V      K+  + + +P+
Sbjct: 1957 YLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQ------VPYGKDFKVDCKASGSPL 2010

Query: 862  PSITWYRN-----NEIISPSETITQN-----FDGENIELVITNVDSEIDSGDYKCVASNS 911
            P I+W        N I+   ++  +      FD   + L    +  E   GDY C A N 
Sbjct: 2011 PDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEE---GDYTCYAENQ 2067

Query: 912  AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969
             G+      +T+         +++  Y    G++VIL+C+ +     K  W     ++  
Sbjct: 2068 LGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIA 2127

Query: 970  MDH-REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQD 1025
            + H R ++ E              D G   C+ ++    +T  + +     P  I  L  
Sbjct: 2128 ISHDRYLLHEN--GSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYS 2185

Query: 1026 FEVKEKDVAILE----VEINSETA---DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
             +   KD AI      ++  +E A    V+W     I                  L IRN
Sbjct: 2186 NKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRN 2245

Query: 1079 TSVHDEGEYSCILRDES----CTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132
                D  E++C+ R++        ++ V+E+   P        + + K +K        +
Sbjct: 2246 IRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAE 2305

Query: 1133 GDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185
            G+    + W   +G+       I     G      IY    DDAG+Y C    +VG  + 
Sbjct: 2306 GNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEK 2365

Query: 1186 TAILTV-EEPSINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTWYKKKS-VIEDTEKF 1242
              IL V ++P+I    R P + I+  A +   L+  +P  +  VTW       IE  +  
Sbjct: 2366 LIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPS--VTWILPSGYAIERPQVQ 2423

Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDY-EREYRI 1299
                 ++  TL+I++    D+  Y C   +    T + V   VV +PP+I +   +    
Sbjct: 2424 GRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPPRITNKPPQTIHT 2483

Query: 1300 KRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKH---TKPSIDSKSASLTIKKVENTDA 1355
            + GS V L       P+P+  W + +  ++        T   +     +L I+  +++D+
Sbjct: 2484 RAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDS 2543

Query: 1356 GIYKLRLENNCG 1367
            GIYK   +N+ G
Sbjct: 2544 GIYKCIAKNSLG 2555



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 157/788 (19%), Positives = 296/788 (37%), Gaps = 68/788 (8%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEI---VPDENISVAIESDMHMYCSVLKITNVK 701
            V  G+ + + C+    P P I W  K E I       N  + ++ D       L I +V 
Sbjct: 1700 VHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPD-----GTLIIKDVT 1754

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESVILSAQVVG 760
             +  G Y  +A N  GE +  + +++      PP ++E  + +++   GE++ +     G
Sbjct: 1755 VYDRGIYRCLATNLAGEDTFTVRIQVIAA---PPVIVEEKRQTVLAGPGENLKIPCTAKG 1811

Query: 761  NPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            NP+PT+ W   +    KP++ +  K    ++    ++     D G Y   A +S G +E 
Sbjct: 1812 NPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTG-SER 1870

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISP 875
              V  + E ++   +      +  E+   +K  + L    T  P P I W   +  ++  
Sbjct: 1871 RVVNLIVEQSDTFPKITDASPKATEMNFGDK--LMLNCTATGEPKPRIIWRLPSKAVVDQ 1928

Query: 876  SETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934
               +        N  L + +V+ + D+GDY CVA N  G      +V++ ++    ++  
Sbjct: 1929 LHRMGSRIQVFPNGTLFVDSVNDK-DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQ 1987

Query: 935  QKSYETEEGKTVILECQTSHT--VSTKW-------YHN--KKEISGMDHREIIQEGRXXX 983
              + +   GK   ++C+ S +      W        +N  + + SG   R  I       
Sbjct: 1988 PLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTL 2047

Query: 984  XXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQD-FEVKEKDVAILEV 1038
                     + G   C  ++Q    E    + V    P     ++  +     +  IL+ 
Sbjct: 2048 YLNKVGIAEE-GDYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDC 2106

Query: 1039 EINSE-TADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR---- 1092
            E N E    + W     ++I    ++Y   + G    L +    + D GEY C+ R    
Sbjct: 2107 EANGEPKPKIFWLLPSSDMIAISHDRYLLHENG---SLTVSQVKLLDAGEYMCVARNPAG 2163

Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL----TKGDA--LVRW-FKDGSE 1145
            D++    + V   PP I     N+ + K        +L     +G A   V W   D   
Sbjct: 2164 DDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIY 2223

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF 1205
            +    H    +  +   L+I +    D  E++C   N    ++L V+   +   LR P F
Sbjct: 2224 LTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEM-LRRPMF 2282

Query: 1206 -------ILVPANTDAYLTVEIP-DETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIR 1256
                    +  ++  A L      + T ++ W         +    +        T II 
Sbjct: 2283 KNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIY 2342

Query: 1257 KCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAF 1314
              T+DD  +Y C   +      KL +  V   P I+ + R   +   G  ++L       
Sbjct: 2343 SPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGM 2402

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
            P+P+  WI+ S    +    +      ++ +L I++    D G Y+ + +N  G   + +
Sbjct: 2403 PRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITV 2462

Query: 1374 NVTILDKP 1381
             V ++  P
Sbjct: 2463 TVVVVAYP 2470



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 177/823 (21%), Positives = 309/823 (37%), Gaps = 99/823 (12%)

Query: 510  PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVAT 567
            P+ VE+ R       G  ++  C  +G P+P + W       IKP Q         +  T
Sbjct: 1785 PVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGT 1844

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            L IR V   D G + C+A ++ G       LIVE   SD   ++T               
Sbjct: 1845 LYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQ--SDTFPKIT--------------- 1887

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
                        PKA  ++ G  ++L C     P+P I W    + +V   +    + S 
Sbjct: 1888 ---------DASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLH---RMGSR 1935

Query: 688  MHMYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSM 744
            + ++ +  L + +V     G Y  VA N+ G+    I++K+    K P ++I  +PL   
Sbjct: 1936 IQVFPNGTLFVDSVNDKDAGDYLCVARNKMGDD--VILMKVSVTMK-PAKIIQKQPLAKQ 1992

Query: 745  IVRQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGD---------THSITILKP 794
             V  G+   +  +  G+P P I+W   +   +  +    D            +    L  
Sbjct: 1993 -VPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNK 2051

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
              + +EG YT  AEN  G  E    ITV       A P + +N           ++ L  
Sbjct: 2052 VGIAEEGDYTCYAENQLGRDEMKVHITV-----VTAAPLIKLNMKTRYAAMAGESVILDC 2106

Query: 855  RVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                 P P I W   ++++I+ S    +    EN  L ++ V   +D+G+Y CVA N AG
Sbjct: 2107 EANGEPKPKIFWLLPSSDMIAISH--DRYLLHENGSLTVSQV-KLLDAGEYMCVARNPAG 2163

Query: 914  KSSHGARVTID-----VEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKW-YHNKKE 966
              +   R+ +      +  +   K + K    +  + +I  + + +  +   W   +   
Sbjct: 2164 DDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIY 2223

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK---- 1022
            ++   H   I   +            D     C+ ++    +MLVV+  + E +R+    
Sbjct: 2224 LTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFK 2283

Query: 1023 ---LQDFEVKEKDVAILE-VEINSETADVVW---ERDGEIIKPKKNKYDFEKRGHIRKLY 1075
                + F  K   +AIL      + T +++W        +  P  +KY     G      
Sbjct: 2284 NPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNG---TFI 2340

Query: 1076 IRNTSVHDEGEYSCILRDE-SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132
            I + +  D G+Y C  R++     ++ ++E+   P I+T  +    +   +A     L+ 
Sbjct: 2341 IYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSD 2400

Query: 1133 G--DALVRW-FKDGSEI---QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
            G     V W    G  I   Q     +L  +G    L I +  L D G Y C+  N    
Sbjct: 2401 GMPRPSVTWILPSGYAIERPQVQGRYKLLENG---TLVIQETALHDRGNYQCKAKNYAGE 2457

Query: 1187 AILTVEEPSINFTLRL----PEFILVPANTDAYLT-VEIPDETLDVTW-YKKKSVIEDTE 1240
              +TV    + +  R+    P+ I   A +   L  + I     D+ W     SV+    
Sbjct: 2458 TAITVTVVVVAYPPRITNKPPQTIHTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTAS 2517

Query: 1241 KFTLISDV---KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
            + +L        + TL+I+     D   Y C+  ++  T   K
Sbjct: 2518 QGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLGTDMSK 2560



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 184/914 (20%), Positives = 339/914 (37%), Gaps = 77/914 (8%)

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNEII 873
            T+ V T        ++P +   +    TV       +    + NP P+I W +  +   +
Sbjct: 1575 TTTVSTSFSTQNSRSKPRIIGGKAASFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFV 1634

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
            S +  + +     N  L I +V  + D G Y CVA+N  G       +++       ++ 
Sbjct: 1635 SKTRRVNKMEVFMNGTLSIPSVGIQ-DGGQYLCVANNQLGSDRLLVTLSVITYPPRILQG 1693

Query: 934  LQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEI---SGMDHREIIQEGRXXXXXXXX 988
              +      G +V + CQ   S   +  W    + I   +   +R+I  +          
Sbjct: 1694 RSREITVHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQP-DGTLIIKD 1752

Query: 989  XXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-- 1043
                D G+ +C+  +   ++T T+ +     P  I + +   V       L++   ++  
Sbjct: 1753 VTVYDRGIYRCLATNLAGEDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGN 1812

Query: 1044 -TADVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
                V W   DG  IKP +             LYIRN +  D G Y CI    S  +E  
Sbjct: 1813 PQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATS-STGSERR 1871

Query: 1102 VVELPPEI------ITRLQNQ--KVNKGNKATFEIELTKGDALVR--WFKDGSEI----- 1146
            VV L  E       IT    +  ++N G+K       T G+   R  W      +     
Sbjct: 1872 VVNLIVEQSDTFPKITDASPKATEMNFGDKLMLNCTAT-GEPKPRIIWRLPSKAVVDQLH 1930

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRL 1202
            +  + IQ+  +G    L +   +  DAG+Y C    ++G+      ++V         + 
Sbjct: 1931 RMGSRIQVFPNGT---LFVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQ 1987

Query: 1203 PEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--------TL 1253
            P    VP   D  +  +     L D++W      + +       S  +KR        TL
Sbjct: 1988 PLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTL 2047

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKI-VDYEREYRIKRGSDVTLLVD 1310
             + K    ++ +YTC   +     ++KV   VV   P I ++ +  Y    G  V L  +
Sbjct: 2048 YLNKVGIAEEGDYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCE 2107

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
                P+P   W++ S  +    H +  +  ++ SLT+ +V+  DAG Y     N  G   
Sbjct: 2108 ANGEPKPKIFWLLPSSDMIAISHDRYLLH-ENGSLTVSQVKLLDAGEYMCVARNPAGDDT 2166

Query: 1371 VEMNVTILDKPSPP------GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
              + + +   P PP         +I++  +   +    + +  G + +    +    I  
Sbjct: 2167 KLLRLEV--HPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYL 2224

Query: 1425 TEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
            T       I   Q     I+N++ + +  F   A N+   S      E  ++++    ++
Sbjct: 2225 TAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKN 2284

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKL----KTAKATYENRXXXX 1536
            P  EK       + ++   L C   G P P++ W   +G +       +K    +     
Sbjct: 2285 PFNEK----FIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFI 2340

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAV 1595
                       Y+C A N  G +E   ++ + QKP ++T     IK    +G+   +  +
Sbjct: 2341 IYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKS--IIGEALSLHCL 2398

Query: 1596 IEGIPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             +G+P P V W   +G  +E  +        +   + I+E        Y  +A N AG +
Sbjct: 2399 SDGMPRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGET 2458

Query: 1655 SVEVTLKVYDKPSK 1668
            ++ VT+ V   P +
Sbjct: 2459 AITVTVVVVAYPPR 2472



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 205/988 (20%), Positives = 376/988 (38%), Gaps = 90/988 (9%)

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSITILKPKKVK 798
            S  V       +  +  GNP PTI W K +       T    K +   +    +    ++
Sbjct: 1600 SFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRVNKMEVFMNGTLSIPSVGIQ 1659

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            D G Y   A N  G      ++T+   T     P +   R +EITV    ++ +  +   
Sbjct: 1660 DGGQYLCVANNQLG--SDRLLVTLSVIT---YPPRILQGRSREITVHSGNSVNVNCQAEG 1714

Query: 859  NPVPSITWYRNNEIISPSETITQN---FDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
            +P P+ITW   NE I P  T T N   F   +  L+I +V +  D G Y+C+A+N AG+ 
Sbjct: 1715 SPFPTITWTLKNETI-PFGTSTSNRKIFVQPDGTLIIKDV-TVYDRGIYRCLATNLAGED 1772

Query: 916  SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWY-HNKKEISGMDH 972
            +   R+ +       V+  +++     G+ + + C  + +   +  W   +  +I  + +
Sbjct: 1773 TFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQY 1832

Query: 973  -REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFI-RKLQ 1024
                +                D G  +CI      S   VV       +T P+      +
Sbjct: 1833 VNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPK 1892

Query: 1025 DFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVH 1082
              E+   D  +L      E    ++W    + +  + ++     +      L++ + +  
Sbjct: 1893 ATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDK 1952

Query: 1083 DEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL- 1136
            D G+Y C+ R    D+    +V+V   P +II +    K     K  F+++    G  L 
Sbjct: 1953 DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQVPYGK-DFKVDCKASGSPLP 2011

Query: 1137 -VRW-FKDGSEIQFSNHIQLTIDGKKQK---------LKIYDCDLDDAGEYSC----EVG 1181
             + W   DG+ I  +N +Q    G++++         L +    + + G+Y+C    ++G
Sbjct: 2012 DISWSLPDGTMI--NNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLG 2069

Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKS-VIEDT 1239
              +    +TV   +    L +       A     L  E   E    + W    S +I  +
Sbjct: 2070 RDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIAIS 2129

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTK-LKVEVVEFPPKIVD-YERE 1296
                L+ +    +L + +    D  EY CV  + A   TK L++EV   PP I   Y  +
Sbjct: 2130 HDRYLLHE--NGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYSNK 2187

Query: 1297 YRIKRGS--DVTLLVDYQAFPQPNDE--WIVNSKI-IKKCKHTKPSIDSKSASLTIKKVE 1351
              IK  +      L+D +A      +  WI+   I +    H    +  ++ +L I+ + 
Sbjct: 2188 SIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIR 2247

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILD---KP---SPPGKPNILEIDSSSINICWDEPE 1405
             +D   +     N+ G + + + + +L+   +P   +P  +  I +    +I  C+ E  
Sbjct: 2248 PSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGN 2307

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT-NSSYRFRAYAVNEVDISDA 1464
             T    II+ +           IS  +     T I    T + + ++R  A N+V   + 
Sbjct: 2308 PT--PEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEK 2365

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-----YRDG 1519
                E  +  K   +  P    P+K+I     E + L C+  G+P+P VTW     Y   
Sbjct: 2366 LIILEVGQ--KPNILTHP--RGPIKSII---GEALSLHCLSDGMPRPSVTWILPSGYAIE 2418

Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579
            +     +                     Y+C A N  GE   +  V +   P   I+N+ 
Sbjct: 2419 RPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPP-RITNKP 2477

Query: 1580 IKQKH-KVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKEYNITTKE---KTSVIRIKE 1634
             +  H + G    +  +  GIP P++ W   + + L    + ++T  E       + I+ 
Sbjct: 2478 PQTIHTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQN 2537

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             + S S  Y   A N+ GT   +  L V
Sbjct: 2538 PQSSDSGIYKCIAKNSLGTDMSKTYLNV 2565



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 135/642 (21%), Positives = 227/642 (35%), Gaps = 58/642 (9%)

Query: 1074 LYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEI 1128
            L I +  + D G+Y C+    L  +     ++V+  PP I+  R +   V+ GN      
Sbjct: 1651 LSIPSVGIQDGGQYLCVANNQLGSDRLLVTLSVITYPPRILQGRSREITVHSGNSVNVNC 1710

Query: 1129 ELTKGD-ALVRWFKDGSEIQF----SNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            +        + W      I F    SN  I +  DG    L I D  + D G Y C   N
Sbjct: 1711 QAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGT---LIIKDVTVYDRGIYRCLATN 1767

Query: 1183 -----SKCTAILTVEEPSINFTLRLPEFILVPA-NTDAYLTVE-IPDETLDVTWY---KK 1232
                 +    I  +  P +    +    +  P  N     T +  P  T+    +   K 
Sbjct: 1768 LAGEDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKI 1827

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPP 1288
            K +     K  L S+    TL IR     D+  Y C+   +  + +    L VE  +  P
Sbjct: 1828 KPLQYVNAKLFLFSN---GTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFP 1884

Query: 1289 KIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASL 1345
            KI D   +   +  G  + L       P+P   W + SK +    H   S      + +L
Sbjct: 1885 KITDASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTL 1944

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405
             +  V + DAG Y     N  G   + M V++  KP+   +   L   +  +    D   
Sbjct: 1945 FVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPL---AKQVPYGKDFKV 2001

Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            +   S      + +   D T    + NI +   S +  +    +      +N+V I++  
Sbjct: 2002 DCKASGSPLPDISWSLPDGT---MINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEG 2058

Query: 1466 ETTEY---------YKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTW 1515
            + T Y          KV       +P ++  +K        E + L C   G P+PK+ W
Sbjct: 2059 DYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFW 2118

Query: 1516 Y---RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572
                 D   +   +                     Y C+A N  G+      + +  KP 
Sbjct: 2119 LLPSSDMIAISHDRYLLHENGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPP 2178

Query: 1573 I---TISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN-KLENDKEYNITTKEKT 1627
            I     SN+  IK         L+    EG  P +V+W    N  L      +     + 
Sbjct: 2179 IINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQN 2238

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669
              + I+ ++ S ++++T  A N  G S + V L+V +   +P
Sbjct: 2239 GTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRP 2280



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 40/184 (21%), Positives = 71/184 (38%), Gaps = 17/184 (9%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + L C    +P P + W+      +    +    +    +    L I        G 
Sbjct: 2390 GEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKL---LENGTLVIQETALHDRGN 2446

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766
            Y   A N  GE ++ + + +      PP++  +P +++  R G +V L+   +G P+P I
Sbjct: 2447 YQCKAKNYAGETAITVTVVVVA---YPPRITNKPPQTIHTRAGSAVRLNCMAIGIPKPDI 2503

Query: 767  TWCKNNKPVKALPTKSDGDTHSITILKPK--------KVKDEGVYTLKAENSEGIAETSA 818
             W      +  L T S G      +L P+        +  D G+Y   A+NS G   +  
Sbjct: 2504 FW--ELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLGTDMSKT 2561

Query: 819  VITV 822
             + V
Sbjct: 2562 YLNV 2565



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 6/84 (7%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAII---KPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            G++V   CQ EG P P ITW  +   I     + + +++   D   TL+I++V   D G 
Sbjct: 1703 GNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPD--GTLIIKDVTVYDRGI 1760

Query: 581  FTCVAKNAAGFASSTTEL-IVEAP 603
            + C+A N AG  + T  + ++ AP
Sbjct: 1761 YRCLATNLAGEDTFTVRIQVIAAP 1784



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 11/119 (9%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTP-DGSTVQFECQ 532
            + +E +YT Y + +L    D++ V     +     AP+    ++ ++    G +V  +C+
Sbjct: 2054 IAEEGDYTCYAENQLGR--DEMKVHITVVTA----APLIKLNMKTRYAAMAGESVILDCE 2107

Query: 533  VEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
              G P+P+I W   ++ +I  S D  + +++    +L + +V   DAG + CVA+N AG
Sbjct: 2108 ANGEPKPKIFWLLPSSDMIAISHDRYLLHEN---GSLTVSQVKLLDAGEYMCVARNPAG 2163



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 520  HTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPE 576
            HT  GS V+  C   G P+P I W     +++  +    +   +      TLVI+     
Sbjct: 2482 HTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSS 2541

Query: 577  DAGTFTCVAKNAAGFASSTTELIV 600
            D+G + C+AKN+ G   S T L V
Sbjct: 2542 DSGIYKCIAKNSLGTDMSKTYLNV 2565



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 49/188 (26%), Positives = 73/188 (38%), Gaps = 12/188 (6%)

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-----ILKPKKVKDEGVY 803
           G +V +  +V+G P P I W   +      P  S     +IT     ILK     D G+Y
Sbjct: 487 GGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDTGIY 546

Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
              A N       S  ITV     E      F+N   E++V     I L    +  P  S
Sbjct: 547 HCIATNYIDADVLSFRITVVSSDVEEQ----FVNGV-ELSVSNGDYINLPCGSSGVPDAS 601

Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++W   +  +   E         N  L I  + SE DSG ++C+A+N  G      RV +
Sbjct: 602 VSWILPDHSVL-YEPSRNKIILANGTLKIQGI-SERDSGHFRCLAANQYGLDILTHRVLV 659

Query: 924 DVEKVTFV 931
              ++  +
Sbjct: 660 KERQINVI 667



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 3/89 (3%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQF-ECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDD 562
            E    P+F      K     S +    C  EG P P+I W                Y+  
Sbjct: 2275 EMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAG 2334

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGF 591
             N  T +I     +DAG + C A+N  G+
Sbjct: 2335 SN-GTFIIYSPTKDDAGKYRCAARNKVGY 2362


>UniRef50_P98160 Cluster: Basement membrane-specific heparan sulfate
            proteoglycan core protein precursor; n=26; Eumetazoa|Rep:
            Basement membrane-specific heparan sulfate proteoglycan
            core protein precursor - Homo sapiens (Human)
          Length = 4391

 Score =  113 bits (272), Expect = 5e-23
 Identities = 178/814 (21%), Positives = 311/814 (38%), Gaps = 104/814 (12%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            PI++E     H  +G T+   C V G    Q+TW+++   + P++         + + L 
Sbjct: 2926 PIYIEA-SSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL-PARH------QTHGSQLR 2977

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            +  V P D+G + C A +  G         V  P S+ GS   +                
Sbjct: 2978 LHLVSPADSGEYVCRAASGPG-PEQEASFTVTVPPSE-GSSYRLRS-------------- 3021

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDM 688
                P  S  P +  V +G D   +C +     P  + W  + +E+  ++N+ ++     
Sbjct: 3022 ----PVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL--EDNVHISPNG-- 3073

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVR 747
                S++ I   +    GTY  VA N  G A   + L +      PP V + P   + V+
Sbjct: 3074 ----SIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVK 3125

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTL 805
             G++V L     G PR +  W + +     L  ++ G  D+H++  +   K  D G Y  
Sbjct: 3126 VGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVC 3185

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A+N+ G A+    + V+        P +      E+TV+   T  L    T +P P+I 
Sbjct: 3186 LAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE-AELTVEAGHTATLRCSATGSPAPTIH 3244

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W   +++ SP        +G+   L+I  V  + DSG Y C A++ AG +   A + + V
Sbjct: 3245 W---SKLRSPLPW-QHRLEGDT--LIIPRVAQQ-DSGQYICNATSPAGHAE--ATIILHV 3295

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983
            E   +   + +    + G+TV L+C    T  ++ +W      + G          R   
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNEL 3349

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043
                     D G  +C V ++  S     +  +      L    +       ++V    E
Sbjct: 3350 LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLE 3409

Query: 1044 TADVVWERDGEIIKPKKNKYD---FEKRGHIRK--------LYIRNTSVHDEGEYSCILR 1092
            T  +    +     P         F++ G +          L I+N     +G Y C   
Sbjct: 3410 TKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAH 3469

Query: 1093 DE----SCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSE 1145
                    +A++ +  LP  +I  R   Q V  G+   FE  L  GD    V W K G  
Sbjct: 3470 GPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFEC-LALGDPKPQVTWSKVGG- 3527

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT----AILTVEE-PSINFTL 1200
                 H++  I      ++I   +L DAG+Y C   N+  T     +L V+  P I+   
Sbjct: 3528 -----HLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQIS--- 3579

Query: 1201 RLPEFILVPANTDA-YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
             +P+ + VPA + A +  +     T D++W K    +         S ++   L++    
Sbjct: 3580 -MPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD------SRLENNMLMLPSVR 3632

Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY 1293
              D   Y C   + +   K     ++ P ++V Y
Sbjct: 3633 PQDAGTYVCTATNRQGKVKAFAH-LQVPERVVPY 3665



 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 260/1257 (20%), Positives = 443/1257 (35%), Gaps = 187/1257 (14%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G TV+  C+  G P   ITW ++   + P    Q   +  ++ATL+I  +   DAG + C
Sbjct: 1970 GRTVRLYCRAAGVPSATITWRKEGGSLPP----QARSERTDIATLLIPAITTADAGFYLC 2025

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            VA + AG A +  + +V    SD                          PP    +  + 
Sbjct: 2026 VATSPAGTAQARIQ-VVVLSASDAS------------------------PPPVKIESSSP 2060

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
             V EG  + L C +       + W  +G  + P   +          + S L++  V   
Sbjct: 2061 SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----------HGSRLRLPQVSPA 2110

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-----------IEPLKSMIVRQGESV 752
              G Y     N  G     I + +  G    P             IEP  S  V +G+++
Sbjct: 2111 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTL 2169

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSE 811
             L+  V G     +TW K      +LP +    TH S+  L      D G Y      + 
Sbjct: 2170 DLNCVVPGQAHAQVTWHKRG---GSLPARH--QTHGSLLRLHQVTPADSGEYVCHVVGTS 2224

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G  E S ++T+E        PP+ I      TV E  T+ L   V       +TWY+   
Sbjct: 2225 GPLEASVLVTIEASVIPGPIPPVRIES-SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGG 2283

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-------SHGARVTID 924
             +     +     G  + +      S  D+G Y C ASN    S       + GA +   
Sbjct: 2284 SLPARHQVR----GSRLYIFQA---SPADAGQYVCRASNGMEASITVTVTGTQGANLAYP 2336

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYH--NKKEISGMDHREIIQEG 979
                  ++    S +  EG+T+ L C     SH   T W+       +    H  +++  
Sbjct: 2337 AGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT-WHKRGGSLPVRHQTHGSLLRLY 2395

Query: 980  RXXXXXXX----XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035
            +                 V +   ++   E +  +      P    +    +V E     
Sbjct: 2396 QASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLD 2455

Query: 1036 LEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            L   +  +  A V W + G  + P +++       H  +L +   +  D GEY C +   
Sbjct: 2456 LNCLVAGQAHAQVTWHKRGGSL-PARHQV------HGSRLRLLQVTPADSGEYVCRVVGS 2508

Query: 1095 SCTAEVTVVELPPEIIT-----------RLQNQKVNKGNKATFEIE---LTKGDALVRWF 1140
            S T E +V+    + ++           R+++   +  N  T ++     ++    + W+
Sbjct: 2509 SGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWY 2568

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE---- 1192
            K G  +  S H    I G   +L+I      D+GEY C V    G+ + + I+T++    
Sbjct: 2569 KRGGSLP-SRH---QIVG--SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622

Query: 1193 --EPSINFTLRLPEF--ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE-------K 1241
               PS++  +R+      +V   T     V        +TWYK+   +           +
Sbjct: 2623 SHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLR 2682

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR 1301
               +S       + R     D  E + V+  + S           P +I           
Sbjct: 2683 LHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGE 2742

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
              D+  +V  QA  Q    W      +     T+ S       L +  V   D+G Y  R
Sbjct: 2743 TLDLNCVVPGQAHAQVT--WHKRGGSLPSHHQTRGS------RLRLHHVSPADSGEYVCR 2794

Query: 1362 LENNCGHADVEMNVTI-------LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            +  + G  +  + VTI       +  P+P G P I  I+ SS  +        G +  + 
Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI-RIEPSSSRVA------EGQTLDLK 2847

Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQN--LKTN--SSYRFRAYAVNEVDISDASETTEY 1470
             VV  Q      W         +  +    L+ N  S      Y+      S   E +  
Sbjct: 2848 CVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVL 2907

Query: 1471 YKVIKET--KIQSPTVEKPL----KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
              +   +   I +P + +P+     +      + ++L C+  G    +VTWY+ G  L  
Sbjct: 2908 VTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPA 2967

Query: 1525 AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-EVETSCVVGIQ---------QKPVIT 1574
               T+ ++               Y C A +  G E E S  V +          + PVI+
Sbjct: 2968 RHQTHGSQ--LRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVIS 3025

Query: 1575 IS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            I   +  ++Q      + L+    +G  P  + W     +LE+    N+      S+I I
Sbjct: 3026 IDPPSSTVQQGQDASFKCLIH---DGAAPISLEWKTRNQELED----NVHISPNGSIITI 3078

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMREISRESVTIE 1686
               + S+   Y   ASN  G +   V L V+  P+    PEGPV ++    ++VT+E
Sbjct: 3079 VGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--VGKAVTLE 3133



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 265/1244 (21%), Positives = 452/1244 (36%), Gaps = 190/1244 (15%)

Query: 505  EQSMAPIFVEKLRPKHT--PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
            E + AP+ VE + P  +  P G +    CQV G P     W R+     PS   Q +   
Sbjct: 1671 ETNQAPLVVE-VHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1729

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXX 621
            +    L    V P DAG + C  +N     +S  EL+V EAP       +TV        
Sbjct: 1730 E----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAP----SKPITV-----TVE 1776

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                  +  G   TF    K++     +  L+  RL     P  A  F G  I+   N+ 
Sbjct: 1777 EQRSQSVRPGADVTFICTAKSK---SPAYTLVWTRLHNGKLPTRAMDFNG--ILTIRNVQ 1831

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
            +   SD   Y  V   +N+    +GT T + V   G  S P+V         PPQ     
Sbjct: 1832 L---SDAGTY--VCTGSNMFAMDQGTAT-LHVQASGTLSAPVV------SIHPPQ----- 1874

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVKDE 800
              + V+ G+         G+P PT+ W     P   LP K+    H  I  L   +  D+
Sbjct: 1875 --LTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQLPAKA--QIHGGILRLPAVEPTDQ 1928

Query: 801  GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
              Y  +A +S G     AV+ V         P + ++  +   V    T++L  R    P
Sbjct: 1929 AQYLCRAHSSAGQQVARAVLHV----HGGGGPRVQVSP-ERTQVHAGRTVRLYCRAAGVP 1983

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
              +ITW +    + P        +  +I  ++    +  D+G Y CVA++ AG +   AR
Sbjct: 1984 SATITWRKEGGSLPPQ----ARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQ--AR 2037

Query: 921  VTIDVEKVTF-----VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR 973
            + + V   +      VK    S    EG+T+ L C  + +   +  WY     +    H 
Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP--PHT 2095

Query: 974  EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETS-TMLVVKET--------IPEFI 1020
            ++                 D G   C V++    +E S T+ V+  T        +P   
Sbjct: 2096 QV----HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGST 2151

Query: 1021 RKLQ----DFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            R ++       V E     L   +  +  A V W + G  + P ++    +  G + +L+
Sbjct: 2152 RPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL-PARH----QTHGSLLRLH 2206

Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEII------TRLQNQKVNKGNKATFEI 1128
                +  D GEY C +   S   E +V V +   +I       R+++         T ++
Sbjct: 2207 --QVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDL 2264

Query: 1129 ELT---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185
                  +  A V W+K G  +   + +      +  +L I+     DAG+Y C   N   
Sbjct: 2265 SCVVAGQAHAQVTWYKRGGSLPARHQV------RGSRLYIFQASPADAGQYVCRASNGME 2318

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD------------VTWYKKK 1233
             +I      +    L  P     P   +   +     +TLD            VTW+K+ 
Sbjct: 2319 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2378

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP------ 1287
                      +        L + + +  D  EY C +L +    +  V V   P      
Sbjct: 2379 G------SLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPA 2432

Query: 1288 ----PKIVDYEREYRIKRGS--DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
                P +       ++  G   D+  LV  QA  Q    W      +   +H        
Sbjct: 2433 LGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVT--WHKRGGSL-PARH-----QVH 2484

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI---LEIDSSSIN 1398
             + L + +V   D+G Y  R+  + G  +  + VTI  + S      +   + I+SSS +
Sbjct: 2485 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWI-------SVKNITKTQTSIQNLKTNSSYRF 1451
            +        G++  +  +V  Q   T  W        S   I  ++  I  +    S  +
Sbjct: 2545 LA------NGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEY 2598

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP----NEDIELTCIFGG 1507
              +  N    + + ET+    +        P+V  P++  ++ P     + ++L C+   
Sbjct: 2599 VCHVSNG---AGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVAR 2655

Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             PQ  +TWY+ G  L +   T+ +                Y C A N+   +E S V+ +
Sbjct: 2656 QPQAIITWYKRGGSLPSRHQTHGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713

Query: 1568 QQ---KPVITISNEDIK----QKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEY 1619
                  P    S+  I+      H    E L +  V+ G    +V W+K G  L +  + 
Sbjct: 2714 SPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ- 2772

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661
                  + S +R+  +  + S +Y      ++G   +SV VT++
Sbjct: 2773 -----TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIE 2811



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 205/1006 (20%), Positives = 354/1006 (35%), Gaps = 118/1006 (11%)

Query: 631  GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            G+ PT   +  +  V EG  + L C +       + W  +G           ++ +   +
Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGG----------SLPARHQV 2483

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLK----SM 744
            + S L++  V     G Y    V   G  EAS+ + ++ +        V  P++    S 
Sbjct: 2484 HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSA 2543

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGV 802
             +  G ++ L+  V      TITW K      +LP++    G    I  + P    D G 
Sbjct: 2544 SLANGHTLDLNCLVASQAPHTITWYKRG---GSLPSRHQIVGSRLRIPQVTP---ADSGE 2597

Query: 803  YTLKAENSEGIAETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            Y     N  G  ETS ++T++        +  PP+ I      TV E  T+ L   V R 
Sbjct: 2598 YVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIES-SSPTVVEGQTLDLNCVVARQ 2656

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P   ITWY+    + PS   T    G ++ L   +  S  DSG+Y C A+N+        
Sbjct: 2657 PQAIITWYKRGGSL-PSRHQTH---GSHLRL---HQMSVADSGEYVCRANNNIDALEASI 2709

Query: 920  RVTIDVE--------KVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWY------- 961
             +++               ++    S    EG+T+ L C     +H   T W+       
Sbjct: 2710 VISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT-WHKRGGSLP 2768

Query: 962  -HNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018
             H++   S   + H      G             +  V+  I     ++  +      P 
Sbjct: 2769 SHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPP 2828

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
               +     V E     L+  +  +  A V W + G  + P +++       H   L + 
Sbjct: 2829 IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNL-PARHQV------HGPLLRLN 2881

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV-VELPPE-------------IITRLQNQKVNKGNK 1123
              S  D GEYSC +   S T E +V V + P              I     +  V +G  
Sbjct: 2882 QVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQT 2941

Query: 1124 ATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
                  +  +  A V W+K G  +  + H          +L+++     D+GEY C   +
Sbjct: 2942 LDLNCVVPGQAHAQVTWYKRGGSLP-ARH-----QTHGSQLRLHLVSPADSGEYVCRAAS 2995

Query: 1183 S---KCTAILTVEEP---SINFTLRLPEFILVPANT------DAYLTVEIPD--ETLDVT 1228
                +  A  TV  P     ++ LR P   + P ++      DA     I D    + + 
Sbjct: 2996 GPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLE 3055

Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287
            W  +   +ED    +    +    + I      +   Y CV  +A    +  V + V  P
Sbjct: 3056 WKTRNQELEDNVHISPNGSI----ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGP 3111

Query: 1288 PKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            P + V  E    +K G  VTL       P+ +  W   S    K +     +    A L 
Sbjct: 3112 PTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQ 3171

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            I   + +DAG Y    +N  G A  ++ V +      PG P + + + + + +       
Sbjct: 3172 ISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQV-QAEEAELTV------E 3224

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
             G++  +          T  W  +++    Q  ++   T    R       +  I +A+ 
Sbjct: 3225 AGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEG-DTLIIPRVAQQDSGQY-ICNATS 3282

Query: 1467 TTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
               + +      ++SP     + ++ + +  E ++L C+  G P     W R G  L   
Sbjct: 3283 PAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PG 3341

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            +AT  N                Y+C   N  G  E    + +Q  P
Sbjct: 3342 RATARNE-LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPP 3386



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 237/1247 (19%), Positives = 431/1247 (34%), Gaps = 144/1247 (11%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            ++ + S  P+ +E   P  T +G T+   C V G    Q+TW+R+   + P       + 
Sbjct: 2044 SASDASPPPVKIESSSPSVT-EGQTLDLNCVVAGSAHAQVTWYRRGGSLPP-------HT 2095

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
              + + L + +V P D+G + C  +N +G   ++  + V      HG+            
Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL-----HGTHSGPSYTP---- 2146

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                   + G       +P + +V EG  + L C +       + W  +G          
Sbjct: 2147 -------VPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGG--------- 2190

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE 739
             ++ +    + S+L++  V     G Y    V   G  EAS+ + ++        P V  
Sbjct: 2191 -SLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRI 2249

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799
               S  V +G+++ LS  V G     +TW K      +LP +       + I +     D
Sbjct: 2250 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG---GSLPARHQVRGSRLYIFQASPA-D 2305

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-----TVKEKGTIKLVA 854
             G Y  +A N     E S  +TV      N   P    +   I      V E  T+ L  
Sbjct: 2306 AGQYVCRASNG---MEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2362

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             V       +TW++       S  +     G  + L      S  DSG+Y C    S+  
Sbjct: 2363 VVPGQSHAQVTWHKR----GGSLPVRHQTHGSLLRLYQA---SPADSGEYVCRVLGSSVP 2415

Query: 915  SSHGARVTID-------VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967
                  VTI+       +     V+    S +  EG+T+ L C  +     +   +K+  
Sbjct: 2416 LEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRG- 2474

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV----KDQETSTMLVVKETIPEFIRKL 1023
              +  R  +   R            D G   C V      QE S ++ +++ +     + 
Sbjct: 2475 GSLPARHQVHGSR---LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQG 2531

Query: 1024 QDFEVK-EKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTS 1080
              + V+ E   A L      +   +V  +    I   K       R  I   +L I   +
Sbjct: 2532 VAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVT 2591

Query: 1081 VHDEGEYSCILRDESCTAEVTVV------------ELPPEIITRLQNQKVNKGNKATFE- 1127
              D GEY C + + + + E +++             + P I     +  V +G       
Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNC 2651

Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS---- 1183
            +   +  A++ W+K G  +  S H           L+++   + D+GEY C   N+    
Sbjct: 2652 VVARQPQAIITWYKRGGSLP-SRH-----QTHGSHLRLHQMSVADSGEYVCRANNNIDAL 2705

Query: 1184 KCTAILTV-------EEPSINFTLRLPEFILVPANTDAY-LTVEIPDET-LDVTWYKKKS 1234
            + + +++V         P  +  +R+       A  +   L   +P +    VTW+K+  
Sbjct: 2706 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2765

Query: 1235 VI---EDTEKFTL----ISDVKKRTLIIRKCTEDDQCEYT-CVLLDAKSTTKLKVEVVEF 1286
             +     T    L    +S       + R        E +  V ++A  ++ + V     
Sbjct: 2766 SLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2825

Query: 1287 PPKIVDYEREYRIKRGS--DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             P I       R+  G   D+  +V  QA  Q    W       K+  +           
Sbjct: 2826 APPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT--W------HKRGGNLPARHQVHGPL 2877

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSP---PGKPNILEIDSSSINIC 1400
            L + +V   D+G Y  ++  + G  +  + VTI    P P   PG    + I++SS ++ 
Sbjct: 2878 LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHV- 2936

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
                   G +  +  VV  Q      W     S+    +T  S   L   S      Y  
Sbjct: 2937 -----TEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVC 2991

Query: 1457 NEVDISDASETTEYYKVIKETK-----IQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQ 1510
                     +   +   +  ++     ++SP +     + T +  +D    C I  G   
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3051

Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
              + W    ++L+       N                Y+C+A N +G  ++   + +   
Sbjct: 3052 ISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGP 3111

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630
            P +++  E      KVG    +  V  G P     W +  +     ++      +  +V+
Sbjct: 3112 PTVSVLPEG-PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVL 3170

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
            +I   K S +  Y   A N  GT+  +V + V      P  P +  E
Sbjct: 3171 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAE 3217



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 158/752 (21%), Positives = 274/752 (36%), Gaps = 88/752 (11%)

Query: 472  QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531
            +Y+   NN    L+  +   I   P    P++   SM PI +E     H  +G T+   C
Sbjct: 2693 EYVCRANNNIDALEASI--VISVSPSAGSPSAPGSSM-PIRIES-SSSHVAEGETLDLNC 2748

Query: 532  QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
             V G    Q+TW ++   + PS      +     + L +  V P D+G + C    ++G 
Sbjct: 2749 VVPGQAHAQVTWHKRGGSL-PS------HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGP 2801

Query: 592  ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651
              ++  + +EA     GS                     G PP    +P +  V EG  +
Sbjct: 2802 LEASVLVTIEA----SGS------------SAVHVPAPGGAPP-IRIEPSSSRVAEGQTL 2844

Query: 652  LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
             L+C +       + W  +G  + P  +          ++  +L++  V     G Y+  
Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNL-PARH---------QVHGPLLRLNQVSPADSGEYSCQ 2894

Query: 712  AVNREGEASLPIVLKIKTGEKEP---PQVIEPL----KSMIVRQGESVILSAQVVGNPRP 764
                 G     +++ I+     P   P + +P+     S  V +G+++ L+  V G    
Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHA 2954

Query: 765  TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
             +TW K    + A   ++ G    + ++ P    D G Y  +A +  G  E  A  TV  
Sbjct: 2955 QVTWYKRGGSLPA-RHQTHGSQLRLHLVSP---ADSGEYVCRAASGPG-PEQEASFTVTV 3009

Query: 825  PTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRNNEIISPSETI 879
            P  E +      P+        TV++         +     P S+ W   N+ +  +  I
Sbjct: 3010 PPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHI 3069

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS-Y 938
            + N  G  I +V T   +    G Y+CVASN+ G +   + V + V     V  L +   
Sbjct: 3070 SPN--GSIITIVGTRPSNH---GTYRCVASNAYGVAQ--SVVNLSVHGPPTVSVLPEGPV 3122

Query: 939  ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
              + GK V LEC ++     S +W       + ++ R                   D G 
Sbjct: 3123 WVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGT 3182

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056
              C+ ++   +    V E I +           + + A L VE    TA +     G   
Sbjct: 3183 YVCLAQNALGTAQKQV-EVIVDTGAMAPGAPQVQAEEAELTVEA-GHTATLRCSATGSPA 3240

Query: 1057 -----KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPE 1108
                    ++   ++ R     L I   +  D G+Y C     +  AE T+   VE PP 
Sbjct: 3241 PTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3300

Query: 1109 IITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
              T  ++  V  G     +  L  G      +W + GS +            + + L   
Sbjct: 3301 ATTVPEHASVQAGETVQLQC-LAHGTPPLTFQWSRVGSSLPG------RATARNELLHFE 3353

Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194
                +D+G Y C    +VG+++  A L V+ P
Sbjct: 3354 RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP 3385



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 217/1116 (19%), Positives = 390/1116 (34%), Gaps = 139/1116 (12%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P     P+   V  G  + L CR   +P   I W  +G  + P      +  +D+    +
Sbjct: 1956 PRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQAR---SERTDI----A 2008

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             L I  +     G Y  VA +  G A   I V+ +   +  PP V     S  V +G+++
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSE 811
             L+  V G+    +TW +      +LP  +    H   +  P+    D G Y  + EN  
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRG---GSLPPHT--QVHGSRLRLPQVSPADSGEYVCRVENGS 2123

Query: 812  GIAETSAVITVEEPTEE--------NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
            G  E S  ++V   T           +  P+ I       V E  T+ L   V       
Sbjct: 2124 GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTLDLNCVVPGQAHAQ 2182

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            +TW++    + P+   T         L+  +  +  DSG+Y C    ++G       VTI
Sbjct: 2183 VTWHKRGGSL-PARHQTHG------SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235

Query: 924  DVE----KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977
            +       +  V+    S    EG+T+ L C  +     +  WY   K    +  R  ++
Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWY---KRGGSLPARHQVR 2292

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET----IPEFIRKLQDFEVKEKD 1032
              R            D G   C   +  E S  + V  T    +       Q   ++   
Sbjct: 2293 GSR---LYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSS 2349

Query: 1033 VAILE---VEIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
              + E   +++N        A V W + G  + P ++    +  G + +LY    S  D 
Sbjct: 2350 SQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL-PVRH----QTHGSLLRLY--QASPADS 2402

Query: 1085 GEYSCILRDESCTAEVTVV-------ELPPEIIT---RLQNQKVNKGNKATFEIE-LTKG 1133
            GEY C +   S   E +V+        +P   +T   R+++         T ++  L  G
Sbjct: 2403 GEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAG 2462

Query: 1134 D--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187
               A V W K G  +   + +         +L++      D+GEY C V    G  + + 
Sbjct: 2463 QAHAQVTWHKRGGSLPARHQVH------GSRLRLLQVTPADSGEYVCRVVGSSGTQEASV 2516

Query: 1188 ILTVEE-------PSINFTLRLPEFILVPANTDAY-LTVEIPDET-LDVTWYKKKSVIED 1238
            ++T+++         + + +R+       AN     L   +  +    +TWYK+   +  
Sbjct: 2517 LVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPS 2576

Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYER 1295
              +      V  R L I + T  D  EY C + +   + +  + V         +     
Sbjct: 2577 RHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSP 2630

Query: 1296 EYRIKRGSDVTL---LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
              RI+  S   +    +D         + I+     K+         +  + L + ++  
Sbjct: 2631 PIRIESSSPTVVEGQTLDLNCVVARQPQAIIT--WYKRGGSLPSRHQTHGSHLRLHQMSV 2688

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409
             D+G Y  R  NN    +  + +++      PS PG    + I+SSS ++   E E    
Sbjct: 2689 ADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGETLDL 2746

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + ++      Q        S+ +  +T+ S   L   S      Y    +  S   E + 
Sbjct: 2747 NCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASV 2806

Query: 1470 YYKV----IKETKIQSPTVEKPLK----NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521
               +         + +P    P++    +      + ++L C+  G    +VTW++ G  
Sbjct: 2807 LVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2866

Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581
            L      +                  Y C      G +E S +V I+      I    + 
Sbjct: 2867 LPARHQVH--GPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLA 2924

Query: 1582 Q--------KHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
            Q         H    + L +  V+ G    +V WYK G  L    + +       S +R+
Sbjct: 2925 QPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTH------GSQLRL 2978

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
              +  + S +Y   A++  G    E +  V   PS+
Sbjct: 2979 HLVSPADSGEYVCRAASGPGPEQ-EASFTVTVPPSE 3013



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 89/415 (21%), Positives = 159/415 (38%), Gaps = 54/415 (13%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G TVQ +C   G P     W R  + +      +          L      PED+G + C
Sbjct: 3313 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARN-------ELLHFERAAPEDSGRYRC 3365

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
               N  G A +  +L+V+ P    GS                  I  G  PT    P+ +
Sbjct: 3366 RVTNKVGSAEAFAQLLVQGP---PGS-------------LPATSIPAGSTPTVQVTPQLE 3409

Query: 644  YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
                G+ +   C + +     + W  +G ++ P  ++             VL+I N+ + 
Sbjct: 3410 TKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDG----------VLRIQNLDQS 3459

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             +GTY   A    G+A     L I+        +   +++++V  G +V      +G+P+
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDPK 3517

Query: 764  PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            P +TW K    ++    +S G    +  +   ++ D G Y   A N+ G  ++  ++ V+
Sbjct: 3518 PQVTWSKVGGHLRPGIVQSGG----VVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ 3573

Query: 824  EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                  A P   I+  QE+ V            +  P P I+W + +  + P   +    
Sbjct: 3574 ------ALPQ--ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL---- 3621

Query: 884  DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
              EN  L++ +V  + D+G Y C A+N  GK    A + +    V +      S+
Sbjct: 3622 --ENNMLMLPSVRPQ-DAGTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTPYSF 3673



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 92/435 (21%), Positives = 153/435 (35%), Gaps = 49/435 (11%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-------EFPPKIVDYEREYRIKRGSDV 1305
            L I      D   Y C+  +A  T + +VEV+          P++   E E  ++ G   
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLEN 1364
            TL       P P   W        K +   P     +  +L I +V   D+G Y     +
Sbjct: 3230 TLRCSATGSPAPTIHW-------SKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATS 3282

Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
              GHA+  +   IL   SPP    + E   +S+          G +  +  +       T
Sbjct: 3283 PAGHAEATI---ILHVESPPYATTVPE--HASVQ--------AGETVQLQCLAHGTPPLT 3329

Query: 1425 TEWISVKNITKTQTSIQN-------LKTNSSYRFRAYAVNEVDISDASETTEYYKV---I 1474
             +W  V +    + + +N            S R+R    N+V  ++A            +
Sbjct: 3330 FQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSL 3389

Query: 1475 KETKI---QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
              T I    +PTV+   +  T      +E  C        ++ W+++G +L    +  + 
Sbjct: 3390 PATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDG 3449

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C A    G+ + S  + IQ  P + I+     Q   VG    
Sbjct: 3450 --VLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVE 3507

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
               +  G P P+V W K G  L           +   V+RI  ++ + + +Y   A+N A
Sbjct: 3508 FECLALGDPKPQVTWSKVGGHLRPG------IVQSGGVVRIAHVELADAGQYRCTATNAA 3561

Query: 1652 GTSSVEVTLKVYDKP 1666
            GT+   V L V   P
Sbjct: 3562 GTTQSHVLLLVQALP 3576



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G TV F C   G P P I W      I PS        +    TL+IR+V   D G +TC
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTC 479

Query: 584 VAKNAAGFASSTTELIVE 601
            A NA G      + ++E
Sbjct: 480 EAMNARGMVFGIPDGVLE 497



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSIT 790
           PPQV+ P +  I   +G++V  +   +G P P I W  N   + + P  T +        
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464

Query: 791 ILKPKKVKDEGVYTLKAENSEGI 813
           I++  K  D+G YT +A N+ G+
Sbjct: 465 IIRDVKESDQGAYTCEAMNARGM 487



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%)

Query: 1550 CIAFNDHGEVETSCV-----VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
            CI  + H + E+ C       G     V+T   E I+     G     T V  G+P P +
Sbjct: 381  CIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASR--GQTVTFTCVAIGVPTPII 438

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             W  N   + +     +T++     + I+++K S    YT EA N  G
Sbjct: 439  NWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486


>UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 3366

 Score =  113 bits (271), Expect = 7e-23
 Identities = 142/664 (21%), Positives = 247/664 (37%), Gaps = 75/664 (11%)

Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166
            II  +++  V  G  A FE  +    D  V W  DG  IQ +  + ++  DGK+ +L + 
Sbjct: 831  IIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLN 890

Query: 1167 DCDLDDAGEYSC-------EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
                DD+G Y+C       E+ +S    ++   EP   FT +L    ++      +    
Sbjct: 891  SVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPL--FTRKLDVLEVIEGRNARFDCKV 948

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII---------------RKCTEDDQC 1264
                   V W      +E+ E   ++ +  + +LII               R    +D+C
Sbjct: 949  SGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDEC 1008

Query: 1265 EYTCVLLDAKSTTKLKVEVVEFPPKIVDYER--EYRIKR-----------------GSDV 1305
                 + + +     ++  +E  P I +     E  I+R                 G + 
Sbjct: 1009 AAELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREA 1068

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
             L       P P   W  N K I   +  K +      SL ++ V +   G+YK  + N 
Sbjct: 1069 VLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCVISNK 1128

Query: 1366 CGHADVEMNVTILD-KPSPP-GKPNILEIDSSSINICWDEPENTGNS---TIIYYVVEYQ 1420
             G A    ++ + D  P PP G P +  I   +I + W +P+    S   + + Y ++ Q
Sbjct: 1129 VGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQ 1188

Query: 1421 EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
             + + +W  + +  K  T +I NL     Y FR  ++     S  S  TE  +++     
Sbjct: 1189 ALGSIQWTIIASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPY 1248

Query: 1480 --QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE------N 1531
              ++P +      +     + + +T     V    VTW R G  L      +E      +
Sbjct: 1249 VQEAPVIIDKPDIVYMVEKQPLSITVTLNHV-NASVTWKRGGVTLSNRPGLFELSMPDDD 1307

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDE 1589
            +                 CIA N +G    SCV+ ++    P      ED+     VG+ 
Sbjct: 1308 QHTLKLCKVKSSDVGQLTCIANNKYGS--DSCVLTLEMAVAPTFETIMEDLDVN--VGET 1363

Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
                 V+EG P P+++WYK    L     +     +    + +   +   S  YT  A N
Sbjct: 1364 PRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKN 1423

Query: 1650 TAGTSSVEVTLKVY--------DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
             AG+ S +  L V+        D P + E   I+R++ R +   +    +  G     K 
Sbjct: 1424 LAGSVSCKAELTVHTSKHLKDKDDPMEDEAS-ILRKMRRLTDYYDVHKEIGRGAFSYVKR 1482

Query: 1702 AIEK 1705
             I+K
Sbjct: 1483 VIQK 1486



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 113/528 (21%), Positives = 203/528 (38%), Gaps = 31/528 (5%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            S+ P+F  KL      +G   +F+C+V G P PQ+ W      ++ ++D ++  +     
Sbjct: 922  SIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGR-H 980

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623
            +L+I  V  ED G +T  A+N+ G      EL V+ P   +S   +++            
Sbjct: 981  SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEV 1040

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
               +I     P F K      V EG + +L C++  +P P I W   G+ I   E+  + 
Sbjct: 1041 PENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMT 1100

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
               D+H     L +  V     G Y  V  N+ G+A+    L +     +PP     ++S
Sbjct: 1101 QFRDVHS----LVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDPPDGAPVVES 1156

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK----D 799
            +    G+++ LS +      P+I        ++     S   T   + LK          
Sbjct: 1157 I---TGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLS 1213

Query: 800  EGV---YTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGTIKLV 853
            +GV   + + +  S+  ++ S      +  +      E P+ I++   + + EK  + + 
Sbjct: 1214 KGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEKQPLSIT 1273

Query: 854  ARVTRNPV-PSITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
              VT N V  S+TW R    +S  P        D +   L +  V S  D G   C+A+N
Sbjct: 1274 --VTLNHVNASVTWKRGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSS-DVGQLTCIANN 1330

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEIS 968
              G  S    +T+++      + + +  +   G+T    +  +        WY     +S
Sbjct: 1331 KYGSDS--CVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLS 1388

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016
               H   + +              D GV  C  K+   S     + T+
Sbjct: 1389 ESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 77/304 (25%), Positives = 125/304 (41%), Gaps = 42/304 (13%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVK 701
            V  G   L EC ++   + D+ WL  G+ I P       +   MH     C +L + +V 
Sbjct: 840  VKAGETALFECHVIGPQDTDVDWLSDGKLIQP-----ALLNCKMHFDGKRCRLL-LNSVH 893

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            +   GTYT      + E +    LK+    +  P     L  + V +G +     +V G 
Sbjct: 894  EDDSGTYTCKLSTAKEELTSSAKLKVIASIE--PLFTRKLDVLEVIEGRNARFDCKVSGT 951

Query: 762  PRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P P + W   ++P++    +    +G  HS+ I+     +DEG+YT+ A NS G  E +A
Sbjct: 952  PPPQVIWSHFDRPLEENEDIRILKEGGRHSL-IISHVSNEDEGLYTVAARNSHGEDECAA 1010

Query: 819  VITVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKL 852
             + V+EP                  EE   P         P F+    ++ V E     L
Sbjct: 1011 ELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVL 1070

Query: 853  VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
              +V   P P+ITW+ N + I  +E   +     ++  ++         G YKCV SN  
Sbjct: 1071 RCKVAGLPYPTITWFHNGKRIDSTED-RKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKV 1129

Query: 913  GKSS 916
            GK++
Sbjct: 1130 GKAT 1133



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 62/202 (30%), Positives = 90/202 (44%), Gaps = 17/202 (8%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNP-RPTITWCK-----NNKPVKALPTKSDGD 785
            +E P +I+  K  IV   E   LS  V  N    ++TW +     +N+P     +  D D
Sbjct: 1250 QEAPVIID--KPDIVYMVEKQPLSITVTLNHVNASVTWKRGGVTLSNRPGLFELSMPDDD 1307

Query: 786  THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
             H++ + K K   D G  T  A N  G    S V+T+E      A  P F    +++ V 
Sbjct: 1308 QHTLKLCKVKS-SDVGQLTCIANNKYG--SDSCVLTLEM-----AVAPTFETIMEDLDVN 1359

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
               T +    V   PVP I WY+ + ++S S   T  +D     LV+ N  ++ DSG Y 
Sbjct: 1360 VGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQAD-DSGVYT 1418

Query: 906  CVASNSAGKSSHGARVTIDVEK 927
            C A N AG  S  A +T+   K
Sbjct: 1419 CTAKNLAGSVSCKAELTVHTSK 1440



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 41/169 (24%), Positives = 83/169 (49%), Gaps = 5/169 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E ++   + G+P P + W+ NG ++++ ++  +T       + ++ +  +H   Y   
Sbjct: 1065 GREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCV 1124

Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702
             SN  G ++    L V D  P  P+G  ++  I+ +++T+ WK P   D  ++ +   YA
Sbjct: 1125 ISNKVGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYA 1184

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            I++    + +W  +A   +   TY I  L++   Y FRV++     FS+
Sbjct: 1185 IQQQALGSIQWTIIASCLKQT-TYTISNLSKGVRYAFRVLSITSKAFSK 1232



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 78/301 (25%), Positives = 121/301 (40%), Gaps = 66/301 (21%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582
            G T  FEC V G     + W     +I+P+  + +M++D      L++  V  +D+GT+T
Sbjct: 843  GETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKR-CRLLLNSVHEDDSGTYT 901

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
            C        +++  EL   A L                       ++  I P F++K   
Sbjct: 902  CK------LSTAKEELTSSAKLK----------------------VIASIEPLFTRKLDV 933

Query: 643  QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
              V EG +   +C++   P P + W      +  +E+I +  E   H     L I++V  
Sbjct: 934  LEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHS----LIISHVSN 989

Query: 703  FQEGTYTVVAVNREGE----ASL-------PIVLKIKTGEKEP-----PQV--------- 737
              EG YTV A N  GE    A L        I  +I   EK P     P+V         
Sbjct: 990  EDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFT 1049

Query: 738  ----IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
                ++PL  M V +G   +L  +V G P PTITW  N K + +   +      D HS+ 
Sbjct: 1050 MPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLV 1109

Query: 791  I 791
            +
Sbjct: 1110 V 1110



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 1/96 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E ++AP F   +       G T +F   VEG P P I W++   ++  S  F   Y DDN
Sbjct: 1342 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVY-DDN 1400

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
              +LV+     +D+G +TC AKN AG  S   EL V
Sbjct: 1401 ECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 9/203 (4%)

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKP 794
            +I P++ ++V+ GE+ +    V+G     + W  + K ++   L  K   D     +L  
Sbjct: 831  IIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLN 890

Query: 795  KKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
               +D+ G YT K   ++    +SA + V    E     PLF  +   + V E    +  
Sbjct: 891  SVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIE-----PLFTRKLDVLEVIEGRNARFD 945

Query: 854  ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             +V+  P P + W   +  +  +E I    +G    L+I++V +E D G Y   A NS G
Sbjct: 946  CKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNE-DEGLYTVAARNSHG 1004

Query: 914  KSSHGARVTIDVEKVTFVKHLQK 936
            +    A + +   +      + K
Sbjct: 1005 EDECAAELYVQEPRPAISSQIAK 1027



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 53/210 (25%), Positives = 97/210 (46%), Gaps = 14/210 (6%)

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGE 1054
            ++KCI+K  + +  +   E     IR ++D  VK  + A+ E   I  +  DV W  DG+
Sbjct: 811  LLKCIIKQGQVARPV---EPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGK 867

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDE-SCTAEVTVV-ELPPEI 1109
            +I+P          G   +L + +    D G Y+C L   ++E + +A++ V+  + P  
Sbjct: 868  LIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPLF 927

Query: 1110 ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
              +L   +V +G  A F+ +++      V W      ++ +  I++  +G +  L I   
Sbjct: 928  TRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHV 987

Query: 1169 DLDDAGEYSCEVGNS----KCTAILTVEEP 1194
              +D G Y+    NS    +C A L V+EP
Sbjct: 988  SNEDEGLYTVAARNSHGEDECAAELYVQEP 1017



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 48/213 (22%), Positives = 86/213 (40%), Gaps = 6/213 (2%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSA 1343
            +FPP      R++ +  G  VTL       P P+  W+ + K ++   +    S      
Sbjct: 2616 DFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQ 2675

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             L I K    DAG+Y+    N          V++   P+ PG P + +   ++  + W  
Sbjct: 2676 LLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVVWRP 2735

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
             + T   T   Y +E +      W+ V   +     ++ +L   +SYRFR   VN+    
Sbjct: 2736 SDTTAPCT---YSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQG 2792

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
              S  +E   V+  T+ Q  +    +K +++ P
Sbjct: 2793 PYSSLSEVV-VLDSTEPQKSSGTVVVKTLSSAP 2824



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 40/121 (33%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 491  KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
            K++K+P      E P +E E+   P FV+ L      +G      C+V G P P ITWF 
Sbjct: 1027 KLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFH 1086

Query: 546  QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
                I  ++D +M    D V +LV+R V     G + CV  N  G A+  + L V   L 
Sbjct: 1087 NGKRIDSTEDRKMTQFRD-VHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILP 1145

Query: 606  D 606
            D
Sbjct: 1146 D 1146



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 29/112 (25%), Positives = 44/112 (39%)

Query: 484  LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543
            L +   +K    P      + E    P+F  KLR     +G  V   C   G P P I+W
Sbjct: 2593 LTRGKKDKTVSQPDIPASIARENDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISW 2652

Query: 544  FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
             +    ++      M    D    L+I +   +DAG + CVA N     +S+
Sbjct: 2653 MKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSS 2704



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 41/192 (21%), Positives = 81/192 (42%), Gaps = 15/192 (7%)

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLT 1155
            E  V+   P+I+  ++ Q ++        + L   +A V W + G  +  SN     +L+
Sbjct: 1251 EAPVIIDKPDIVYMVEKQPLS------ITVTLNHVNASVTWKRGG--VTLSNRPGLFELS 1302

Query: 1156 I-DGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVEEP-SINFTLRLPEFILVPAN 1211
            + D  +  LK+      D G+ +C   N     + +LT+E   +  F   + +  +    
Sbjct: 1303 MPDDDQHTLKLCKVKSSDVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGE 1362

Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
            T  +  V       D+ WYK  +++ ++  FT + D  + +L++     DD   YTC   
Sbjct: 1363 TPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAK 1422

Query: 1272 DAKSTTKLKVEV 1283
            +   +   K E+
Sbjct: 1423 NLAGSVSCKAEL 1434



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
            PP     L+  ++ +G+ V LS    G+P P I+W K+ KP++  P     S  D   + 
Sbjct: 2618 PPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLL 2677

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            ++     KD G+Y   A N      +S V+++
Sbjct: 2678 MIMKTTKKDAGLYECVAANPLATVTSSCVVSL 2709



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 45/208 (21%), Positives = 82/208 (39%), Gaps = 15/208 (7%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536
            P     L++      + + L+C+  G P P ++W +D K L+        +  + R    
Sbjct: 2619 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLM 2678

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y+C+A N    V +SCVV + + P  +    ++ QK+K     +V    
Sbjct: 2679 IMKTTKKDAGLYECVAANPLATVTSSCVVSLARLP-NSPGTPEVPQKYK-NTALVVWRPS 2736

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAG--- 1652
            +   P     Y    K E +  + I  T        + +L    S ++ +   N AG   
Sbjct: 2737 DTTAP---CTYSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQGP 2793

Query: 1653 -TSSVEVTLKVYDKPSKPEGPVIMREIS 1679
             +S  EV +    +P K  G V+++ +S
Sbjct: 2794 YSSLSEVVVLDSTEPQKSSGTVVVKTLS 2821



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 9/118 (7%)

Query: 993  DVGVIKCIVKDQ--ETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETA-DVV 1048
            DVG + CI  ++    S +L ++  + P F   ++D +V   +     V +  +   D++
Sbjct: 1320 DVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDIL 1379

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102
            W + G+ +  + + + F    +   L + NT   D G Y+C  ++     SC AE+TV
Sbjct: 1380 WYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436


>UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 667

 Score =  112 bits (270), Expect = 9e-23
 Identities = 136/663 (20%), Positives = 253/663 (38%), Gaps = 63/663 (9%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892
            P F+ R +  ++       L   +  NPVP +TW +    IS         DG+   L I
Sbjct: 10   PRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTI 69

Query: 893  TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK---HLQKSYETEEGK--TVI 947
             ++  E DSG Y C A N+ G++     + + + +    +    + K   T  G    V 
Sbjct: 70   YDLTLE-DSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPVSTRVGLGGDVT 128

Query: 948  LECQTS-HTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005
              C+ S H      W  + + +   +  +I  E              D G   C V++  
Sbjct: 129  FYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRSLDSGTYNCRVQNS- 187

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF 1065
                +   ++    +  LQD         +L  + ++     + +R  E+    +    F
Sbjct: 188  ----IGRAQSAATLVVDLQDTH-------LLNADKSTSLLSHMQKRKQEM----RTDISF 232

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125
             +          +T + +E     + RD+          LP  + TR     V +G  A 
Sbjct: 233  YRTTESSSTTSSSTKITEEHGSFGLARDQEQRVSALTSMLPKGVFTRTCT--VTEGKHAK 290

Query: 1126 FEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN- 1182
                +T      + W KDG+ I +   H+      +   LK+  C   D G Y+C   N 
Sbjct: 291  LSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYTCNASNL 350

Query: 1183 -----------------------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
                                   ++  + + V++P I F  +L + + V     A L  E
Sbjct: 351  AGQTYSAVLVIVKGTLEKGHRNLAEYQSTIAVQKPKIPFKKKLQD-VEVKEKETATLQCE 409

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279
            +P      +W+ +++ +E   K+ +  +   R L IR  T +D   Y C + +   T   
Sbjct: 410  VPVSNTKASWFMEETRLEQNTKYRMDEEGTLRRLTIRNVTTNDDAVYICEMNEGSRTVAE 469

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
               +     K+    R   +     V   V+ +  P  +  W  N + +K+      +  
Sbjct: 470  LTVLGNITKKL---PRRTVVPVSDTVIFCVELEK-PVDDAYWTRNGERLKEDSRIIIARV 525

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--PSPPGKPNILEIDSSSI 1397
            ++  +LTI++    D+G     + ++C       +VT   K  P PP +P +     SSI
Sbjct: 526  NRQYTLTIRECTAEDSGEVAF-IAHDC-KTSTRFSVTAPRKHPPDPPVEPIVQNKTDSSI 583

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455
             +CW  P++     I  Y+VE +++ T  W+ +    ++ T+ +I ++   +SY+FR  A
Sbjct: 584  TLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTKYTITDVLEETSYQFRISA 643

Query: 1456 VNE 1458
            VN+
Sbjct: 644  VND 646



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 63/236 (26%), Positives = 108/236 (45%), Gaps = 16/236 (6%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
           P+ +   K+  +  G    LS  +VGNP P +TW K    + A     T  DGD + +TI
Sbjct: 10  PRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTI 69

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
                ++D G Y  +A+N+ G A  +  + V  P       P+FI +     V   G + 
Sbjct: 70  YD-LTLEDSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPVSTRVGLGGDVT 128

Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911
              RV+ +P P+  W ++   +  +  I    + ++  L I +V S +DSG Y C   NS
Sbjct: 129 FYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRS-LDSGTYNCRVQNS 187

Query: 912 AGKSSHGARVTIDVE---------KVTFVKHLQKSYETEEGKTVILECQTSHTVST 958
            G++   A + +D++           + + H+QK    +E +T I   +T+ + ST
Sbjct: 188 IGRAQSAATLVVDLQDTHLLNADKSTSLLSHMQK--RKQEMRTDISFYRTTESSST 241



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 1/155 (0%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P  +  W +NG +L+ D    I    +   + I+E     S +    A +   ++   VT
Sbjct: 501  PVDDAYWTRNGERLKEDSRIIIARVNRQYTLTIRECTAEDSGEVAFIAHDCKTSTRFSVT 560

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
                  P  P  P++  +    S+T+ W PP  +  + +T Y +E+ +     W+K+   
Sbjct: 561  APRKHPPDPPVEPIVQNKTD-SSITLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTT 619

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754
                  Y I  + E   Y FR+ A N  G S  LE
Sbjct: 620  PVSTTKYTITDVLEETSYQFRISAVNDFGQSAYLE 654



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 13/202 (6%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           L G  P F  +PKA  +  G D  L C +V  P P + W  +   I          + D+
Sbjct: 5   LFGGAPRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDI 64

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744
           +     L I ++     G Y   A N  GEA   + LK+       E+ P  +++P+ S 
Sbjct: 65  YR----LTIYDLTLEDSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPV-ST 119

Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEG 801
            V  G  V    +V  +P P   W K+ +       +   S+ D+ S+ I   + + D G
Sbjct: 120 RVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRSL-DSG 178

Query: 802 VYTLKAENSEGIAETSAVITVE 823
            Y  + +NS G A+++A + V+
Sbjct: 179 TYNCRVQNSIGRAQSAATLVVD 200



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 33/85 (38%), Positives = 46/85 (54%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            PP  P   +V   T  S+TL W+ P+S    PIT YI+E + V  ++W KI T   S  +
Sbjct: 566  PPDPPVEPIVQNKTDSSITLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTK 625

Query: 1925 HCIENIKEKDEIIFRISAENTVGVS 1949
            + I ++ E+    FRISA N  G S
Sbjct: 626  YTITDVLEETSYQFRISAVNDFGQS 650



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 59/219 (26%), Positives = 83/219 (37%), Gaps = 28/219 (12%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP F+ + +      G      C + G P P +TW ++   I     F+   D D +  L
Sbjct: 9   APRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGD-IYRL 67

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            I ++  ED+G + C AKN  G A +   L V  P      E  V               
Sbjct: 68  TIYDLTLEDSGQYMCRAKNTVGEAYAAVTLKVGLP------ETVVERA------------ 109

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
                P F  KP +  V  G D+   CR+ A P P+  W   G  +     I +  ESD 
Sbjct: 110 -----PVFIVKPVSTRVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESD- 163

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
               S L+I +V+    GTY     N  G A     L +
Sbjct: 164 ---SSSLRIQSVRSLDSGTYNCRVQNSIGRAQSAATLVV 199



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP  P+      S+I +  W  P+ +   P+ GY +  R V    W+++    V+T K
Sbjct: 567  PDPPVEPIVQNKTDSSITLC-WSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTK 625

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            + I D+ E  +Y  RI A N+ G S  LE
Sbjct: 626  YTITDVLEETSYQFRISAVNDFGQSAYLE 654



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP+F+ K        G  V F C+V  +P P   W +    +  +   ++  + D+ ++L
Sbjct: 109 APVFIVKPVSTRVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDS-SSL 167

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            I+ V   D+GT+ C  +N+ G A S   L+V+
Sbjct: 168 RIQSVRSLDSGTYNCRVQNSIGRAQSAATLVVD 200



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 26/82 (31%), Positives = 36/82 (43%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G   +  C V G+P+PQI W +    I   +   MY D      L +      D G +T
Sbjct: 285 EGKHAKLSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYT 344

Query: 583 CVAKNAAGFASSTTELIVEAPL 604
           C A N AG   S   +IV+  L
Sbjct: 345 CNASNLAGQTYSAVLVIVKGTL 366



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 13/176 (7%)

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX--YKCIAF 1553
            D  L+C   G P P VTW ++  ++       T E+                  Y C A 
Sbjct: 26   DASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTIYDLTLEDSGQYMCRAK 85

Query: 1554 NDHGEVETSCV--VG-----IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
            N  GE   +    VG     +++ PV  +  + +  +  +G +      +   P P   W
Sbjct: 86   NTVGEAYAAVTLKVGLPETVVERAPVFIV--KPVSTRVGLGGDVTFYCRVSAHPAPNFDW 143

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             K+G  L       IT++  +S +RI+ ++   S  Y     N+ G +    TL V
Sbjct: 144  EKDGRYLGETNRIKITSESDSSSLRIQSVRSLDSGTYNCRVQNSIGRAQSAATLVV 199



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 3/73 (4%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            ++  + G P P+++W K+G  + E  +      + +  ++++   K+S +  YT  ASN 
Sbjct: 291  LSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYTCNASNL 350

Query: 1651 AGT--SSVEVTLK 1661
            AG   S+V V +K
Sbjct: 351  AGQTYSAVLVIVK 363


>UniRef50_UPI0000D5788D Cluster: PREDICTED: similar to CG31738-PB,
            isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG31738-PB, isoform B - Tribolium castaneum
          Length = 965

 Score =  112 bits (270), Expect = 9e-23
 Identities = 103/412 (25%), Positives = 172/412 (41%), Gaps = 31/412 (7%)

Query: 1642 KYTIEASNTAGTS--SVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
            K+ + A N  G S  S EVT +   D+P +P  PV+   I   S  ++W+PP   GG ++
Sbjct: 312  KFRLRAENDGGQSPWSDEVTYQTLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADI 371

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            T+Y +   E ++    +V     + E  C  KL     Y  R    +  G S    S P 
Sbjct: 372  TEYIL---EVNSGSGYEVVYTGTETEAVC-DKLTPGTTYQLRASCISAGGRSN--YSNPC 425

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK-XXX 1817
             + T    P             + S+ I W   + NGG+P+++Y+VE+       +    
Sbjct: 426  TVTTDAIAPGQCAAPRLHGKPKSSSITIRWCEPDYNGGAPVLEYEVEMAGPPDHTRNLVH 485

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                       L+    Y+F + A N IG  L ++   K+T G    PP        +  
Sbjct: 486  KSKETECTAANLTPGCEYEFFVRAVNRIGPGL-WSDPLKVTSG--AAPPDVIETLATNCK 542

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
            +   + ++W EP SN G+PI +Y +E  T         +   G+ + H ++ +       
Sbjct: 543  SPFHIFVEWREPPSN-GAPILDYRLEISTSNNDFH---LVYQGAENYHDVKGLSPFTTYY 598

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGA 1996
            FR+ A N+ G SL +   +       T  +PP++   +R   +   +T +W  P  + G+
Sbjct: 599  FRVQACNSAGCSLYSPVAAT-----VTPAAPPSSVTTLRSDSTPTSITLNWNEPS-NNGS 652

Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             +  YNI   D       ++   D    ++ I +L    TY I+I A N IG
Sbjct: 653  EITHYNIEFGD-------KLIVTDGPVREYQIDNLQPETTYKIKIQAVNAIG 697



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 60/244 (24%), Positives = 95/244 (38%), Gaps = 20/244 (8%)

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVI-------RIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            W +  N       YNI   +K  V        +I  L+   + K  I+A N  GT S+  
Sbjct: 644  WNEPSNNGSEITHYNIEFGDKLIVTDGPVREYQIDNLQPETTYKIKIQAVNAIGTGSLSS 703

Query: 1659 TLKVYDKPSKPEGPVI-MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717
            TLKV      P  P +    I    + ++W    D   ++ T Y IE    +N R     
Sbjct: 704  TLKVSTLKLPPAAPRLECIGIGHNYLKLKWG---DGKNVDYTHYLIEM---ENGRTHDFQ 757

Query: 1718 DVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776
             V +    TY + KL+E   Y FR+ A N  G  +   S+     T++  P         
Sbjct: 758  CVYKGTALTYKVNKLHELTTYRFRICASNDAGVGDF--SDIYEFTTSI-APPAVVKQPKL 814

Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKLSINTTY 1835
              +D  S  I W PS+     P+I ++V++ + + + +K           I+ L     Y
Sbjct: 815  IEVDQTSCVIEWMPSKNQFVDPVI-FQVQVARVKDQFFKETYRGAESKCSIENLESGVEY 873

Query: 1836 QFRI 1839
              R+
Sbjct: 874  SARV 877



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 58/225 (25%), Positives = 93/225 (41%), Gaps = 17/225 (7%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
            S+ + W  S  + GS I  Y +E  + +G  +            I KL   T Y+FR+ A
Sbjct: 169  SLQLKW-NSVNDNGSHITCYILEYDEGKGGDFVEFHRGRVKQYTIHKLQPATPYRFRLAA 227

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
             NEIG S  Y+  + +T      PP++P   V++E++   + L+W++  S+         
Sbjct: 228  MNEIGKS-GYS--EVVTYNTCNNPPTKPPPPVLAEASINYLHLQWSKRPSDE-------- 276

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCI-ENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             EF      S T    V       CI   +    E  FR+ AEN  G S    S  V  +
Sbjct: 277  -EFTLQMNDSRTSYRPVYNGRETICICTGLSNFTEYKFRLRAENDGGQS--PWSDEVTYQ 333

Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005
                 P  P+ P+    + ++     W  P + GGA +  Y + +
Sbjct: 334  TLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADITEYILEV 378



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 78/336 (23%), Positives = 124/336 (36%), Gaps = 26/336 (7%)

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
            D   N+  K K +      L      ++ + A N  G       LKV    + P+    +
Sbjct: 478  DHTRNLVHKSKETECTAANLTPGCEYEFFVRAVNRIGPGLWSDPLKVTSGAAPPDVIETL 537

Query: 1676 REISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLN 1732
                +    + +EW+ P  +G   +  Y +E    +N+  +    V +  E Y  ++ L+
Sbjct: 538  ATNCKSPFHIFVEWREPPSNGA-PILDYRLEISTSNNDFHL----VYQGAENYHDVKGLS 592

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
                Y FRV A N  G S  L S      T    PS              S+ + W    
Sbjct: 593  PFTTYYFRVQACNSAGCS--LYSPVAATVTPAAPPSSVTTLRSDST--PTSITLNW-NEP 647

Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852
             N GS I  Y +E    G K            +I  L   TTY+ +I A N IGT    +
Sbjct: 648  SNNGSEITHYNIEF---GDKL-IVTDGPVREYQIDNLQPETTYKIKIQAVNAIGTG---S 700

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912
                + +     PP+ PR   +       + LKW + ++      T+Y+IE +   G++ 
Sbjct: 701  LSSTLKVSTLKLPPAAPRLECIGIG-HNYLKLKWGDGKN---VDYTHYLIEME--NGRTH 754

Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
                   G+   + +  + E     FRI A N  GV
Sbjct: 755  DFQCVYKGTALTYKVNKLHELTTYRFRICASNDAGV 790



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 1/91 (1%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
            +P  P  P + +   +S+ + W+   + G S I  Y++EY E    +++        Q +
Sbjct: 153  EPDQPQPPKLHQRQKTSLQLKWNSVNDNG-SHITCYILEYDEGKGGDFVEFHRGRVKQYT 211

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            I  L+  + YRFR  A+NE+  S  SE   Y
Sbjct: 212  IHKLQPATPYRFRLAAMNEIGKSGYSEVVTY 242



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 43/173 (24%), Positives = 71/173 (41%), Gaps = 13/173 (7%)

Query: 1802 YKVEIKQEGK--KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
            Y+V +  + K  K+K          RI+ L     Y   +    +    L   + D +  
Sbjct: 91   YEVLLSDKSKEMKFKSIYSGTSLSCRIRDLKPGQEYSVCLQVHYD---ELQGAATDPVKF 147

Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919
                  P QP+   + +    S+ LKW     N GS IT YI+E+   KG  + +     
Sbjct: 148  TTPPCEPDQPQPPKLHQRQKTSLQLKWNSVNDN-GSHITCYILEYDEGKGGDFVEFHR-- 204

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972
            G V ++ I  ++      FR++A N +G S  +E     +  + T  +PPT P
Sbjct: 205  GRVKQYTIHKLQPATPYRFRLAAMNEIGKSGYSE-----VVTYNTCNNPPTKP 252



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 6/104 (5%)

Query: 1358 YKLRLENNCGHADVEMNVT---ILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTII 1413
            ++LR EN+ G +     VT   + D+P  P KP +   I + S  + W+ P  TG + I 
Sbjct: 313  FRLRAENDGGQSPWSDEVTYQTLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADIT 372

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             Y++E       E   V   T+T+     L   ++Y+ RA  ++
Sbjct: 373  EYILEVNSGSGYE--VVYTGTETEAVCDKLTPGTTYQLRASCIS 414



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 8/88 (9%)

Query: 1382 SPPGKPNILEIDSS--SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439
            +PP     L  DS+  SI + W+EP N G S I +Y +E+      + + V +    +  
Sbjct: 623  APPSSVTTLRSDSTPTSITLNWNEPSNNG-SEITHYNIEF-----GDKLIVTDGPVREYQ 676

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASET 1467
            I NL+  ++Y+ +  AVN +     S T
Sbjct: 677  IDNLQPETTYKIKIQAVNAIGTGSLSST 704



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 12/141 (8%)

Query: 1358 YKLRLE--NNCGHADVEMNVTILDKPSPPGKPNI--LEIDSSSINICWDEPENTGNSTII 1413
            YK++++  N  G   +   + +     PP  P +  + I  + + + W + +N   +   
Sbjct: 686  YKIKIQAVNAIGTGSLSSTLKVSTLKLPPAAPRLECIGIGHNYLKLKWGDGKNVDYT--- 742

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            +Y++E +   T ++  V   T     +  L   ++YRFR  A N+  + D S+  E+   
Sbjct: 743  HYLIEMENGRTHDFQCVYKGTALTYKVNKLHELTTYRFRICASNDAGVGDFSDIYEF--- 799

Query: 1474 IKETKIQSPTVEKPLKNITTE 1494
               T I  P V K  K I  +
Sbjct: 800  --TTSIAPPAVVKQPKLIEVD 818


>UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd protein,
            partial; n=5; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to Ptprd protein, partial -
            Strongylocentrotus purpuratus
          Length = 1773

 Score =  112 bits (269), Expect = 1e-22
 Identities = 126/537 (23%), Positives = 213/537 (39%), Gaps = 36/537 (6%)

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546
            P + +  E N    + C   G P+P++ W+++   ++                       
Sbjct: 76   PRRYMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRISMTDSGLQFSRAQLSDQG 135

Query: 1547 XYKCIAFNDHG---EVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
             Y+C A N  G    VE    V  +Q +P  TI  E+  Q+   G    +T    G P P
Sbjct: 136  RYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPEN--QEVVPGGSVNLTCAAYGSPMP 193

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             V W K G  L++  +  I      +V++++++    S+ YT  A++  GT      + V
Sbjct: 194  RVRWMKAGMDLDDMDDLPI----GRNVLQLRDI--YESANYTCVATSLLGTIDTSARVTV 247

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDR 1721
              +PS P  PV+    S  S+T+EW     D    +T + +E K       + ++     
Sbjct: 248  RTRPSVPNSPVVTGYTS-SSLTVEWSTLSSD---TVTSHVLEYKRSRSGGSFTEMEIPSP 303

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
               ++ I+ L    EY  R++A N +G S    S+ +   T  DVPS          I  
Sbjct: 304  QDTSFTIEGLLPYTEYAVRLLAVNSIGRSN--PSDEVTAMTGEDVPS-QPEQFEGVAISA 360

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
              + +TW   +      II Y++                      +  L  NT Y  R+ 
Sbjct: 361  SQIRLTWMMRDTE--PQIIRYELYYNVSTNDNDMHKTITPTTDYVLDNLRPNTLYHIRLA 418

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV-SESTSRSVTLKWTEP--ESNGGSPI 1897
            AR+E G      S   IT+    + P  P   V  +  +S S+ ++W+ P  E   G  I
Sbjct: 419  ARSETGEG---ASSPVITVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGD-I 474

Query: 1898 TNYIIEFK---TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
            T Y I ++    V   +    V V   V  + +E +++      R+ A   +G   P++S
Sbjct: 475  TGYKIIYRKMSLVSTNNPEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSDS 534

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTK 2010
             S+R  + A  P  P   + +R+  S  +   W  P+ D     + GY I  + VT+
Sbjct: 535  LSIRTAEDA--PEGPPRKVRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTVTE 589



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 114/517 (22%), Positives = 191/517 (36%), Gaps = 40/517 (7%)

Query: 1407 TGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            TGN    I +  E+  I+  + IS+   T +       + +   R+   A N +    + 
Sbjct: 95   TGNPEPEILWFKEFVPIEANDRISM---TDSGLQFSRAQLSDQGRYECAAKNSLGTRYSV 151

Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525
            E   Y   +K+ +++      P +N    P   + LTC   G P P+V W + G  L   
Sbjct: 152  EAQVY---VKDRQVEPRFTILP-ENQEVVPGGSVNLTCAAYGSPMPRVRWMKAGMDLDDM 207

Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK 1585
                  R               Y C+A +  G ++TS  V ++ +P  ++ N  +   + 
Sbjct: 208  DDLPIGR--NVLQLRDIYESANYTCVATSLLGTIDTSARVTVRTRP--SVPNSPVVTGYT 263

Query: 1586 VGD---EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
                  EW  + +        V+ YK      +  E  I + + TS   I+ L       
Sbjct: 264  SSSLTVEW--STLSSDTVTSHVLEYKRSRSGGSFTEMEIPSPQDTS-FTIEGLLPYTEYA 320

Query: 1643 YTIEASNTAGTS--SVEVT-LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699
              + A N+ G S  S EVT +   D PS+PE       IS   + + W   + D   ++ 
Sbjct: 321  VRLLAVNSIGRSNPSDEVTAMTGEDVPSQPE-QFEGVAISASQIRLTWM--MRDTEPQII 377

Query: 1700 KYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            +Y +  +   N N   K      D   Y +  L  N  Y  R+ A++  G  E   S  I
Sbjct: 378  RYELYYNVSTNDNDMHKTITPTTD---YVLDNLRPNTLYHIRLAARSETG--EGASSPVI 432

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNG---GSPIIDYKVE-IKQEGK 1811
             ++T    P           + + S+ + W P    ++NG   G  II  K+  +     
Sbjct: 433  TVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGDITGYKIIYRKMSLVSTNNP 492

Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
            +             ++ L   T Y  R+ A   IG   P  SD          P   PR 
Sbjct: 493  EMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPP--SDSLSIRTAEDAPEGPPRK 550

Query: 1872 FVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKTV 1907
              V    S ++ ++W  P+ +     I  Y I+++TV
Sbjct: 551  VRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTV 587



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 55/230 (23%), Positives = 90/230 (39%), Gaps = 16/230 (6%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           P     P + M+V       +     GNP P I W K   P++A    S   T S     
Sbjct: 70  PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRIS--MTDSGLQFS 127

Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
             ++ D+G Y   A+NS G   T   +  +   ++    P F    +   V   G++ L 
Sbjct: 128 RAQLSDQGRYECAAKNSLG---TRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLT 184

Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                +P+P + W +    +   + +     G N+ L + ++    +S +Y CVA++  G
Sbjct: 185 CAAYGSPMPRVRWMKAGMDLDDMDDLP---IGRNV-LQLRDI---YESANYTCVATSLLG 237

Query: 914 KSSHGARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959
                ARVT+     V     V     S  T E  T+  +  TSH +  K
Sbjct: 238 TIDTSARVTVRTRPSVPNSPVVTGYTSSSLTVEWSTLSSDTVTSHVLEYK 287



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 57/207 (27%), Positives = 94/207 (45%), Gaps = 16/207 (7%)

Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
            + TSL  T D    +    T PS P + VV+  TS S+T++W+   S+    +T++++E+
Sbjct: 231  VATSLLGTIDTSARV-TVRTRPSVPNSPVVTGYTSSSLTVEWSTLSSD---TVTSHVLEY 286

Query: 1905 KTVK-GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
            K  + G S+T++           IE +    E   R+ A N++G S P  S  V      
Sbjct: 287  KRSRSGGSFTEMEIPSPQDTSFTIEGLLPYTEYAVRLLAVNSIGRSNP--SDEVTAMTGE 344

Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL--LGYNIAIRDVTKTMWMEVGKVDV 2021
             VPS P     + +  S I +T W   + +       L YN++  D       ++ K   
Sbjct: 345  DVPSQPEQFEGVAISASQIRLT-WMMRDTEPQIIRYELYYNVSTND------NDMHKTIT 397

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIG 2048
             T  + + +L  N  Y IR+ AR+E G
Sbjct: 398  PTTDYVLDNLRPNTLYHIRLAARSETG 424



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 52/202 (25%), Positives = 82/202 (40%), Gaps = 15/202 (7%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           G P   S   +   V+      + C     PEP+I W FK  E VP     +     + M
Sbjct: 68  GYPEITSNPRRYMVVENNRPATIYCGATGNPEPEILW-FK--EFVP-----IEANDRISM 119

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             S L+ +  +   +G Y   A N  G   S+   + +K  + EP   I P    +V  G
Sbjct: 120 TDSGLQFSRAQLSDQGRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVV-PG 178

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            SV L+    G+P P + W K    +  +     G      +L+ + + +   YT  A +
Sbjct: 179 GSVNLTCAAYGSPMPRVRWMKAGMDLDDMDDLPIGR----NVLQLRDIYESANYTCVATS 234

Query: 810 SEGIAETSAVITVE-EPTEENA 830
             G  +TSA +TV   P+  N+
Sbjct: 235 LLGTIDTSARVTVRTRPSVPNS 256



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 60/284 (21%), Positives = 104/284 (36%), Gaps = 21/284 (7%)

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKPPL 1691
            +L+     ++ + ASN  G S+  +      + +    P  V    +S  S+++ W PPL
Sbjct: 710  DLRLGTRYEFKLTASNEEGNSNEAIFYYTTHEGTPSGSPMNVTASPLSSSSISVSWDPPL 769

Query: 1692 DD--GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749
            ++   GL L KY I  +       +     + D+    +  L  N  Y   V A   VG 
Sbjct: 770  EEERNGLIL-KYTIRYYSSAMPTELTNRTTETDI---VLTSLVPNTAYSVEVRAHTSVG- 824

Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGGSPIIDYKVEIKQ 1808
                 S   +  T  + P+               + + W  PS      P  +Y V    
Sbjct: 825  -PGPYSTKDIATTPREAPASAPLDLRCAAPHGTQLEVKWSHPSNIQRSGPGYNYLVYSTN 883

Query: 1809 EGKK-----W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
                     W +           ++ L   TTY   +      G S P +    IT    
Sbjct: 884  SADNTDVSTWGRPVSAGEFTKLELRGLQEETTYYVAVKLDTPEGNS-PLSQI--ITCLTG 940

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
             + PS+PR+F    ++  ++ L W+EP    G  + +Y+I++ T
Sbjct: 941  TSAPSEPRSFDAHIASDNTINLVWSEPSDIPGR-LKDYVIKYHT 983



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 49/251 (19%), Positives = 95/251 (37%), Gaps = 25/251 (9%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-----TKLK 1280
            ++ W+K+   IE  ++ ++        L   +    DQ  Y C   ++  T      ++ 
Sbjct: 101  EILWFKEFVPIEANDRISMTDS----GLQFSRAQLSDQGRYECAAKNSLGTRYSVEAQVY 156

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V+  +  P+         +  G  V L       P P   W+       K       +D 
Sbjct: 157  VKDRQVEPRFTILPENQEVVPGGSVNLTCAAYGSPMPRVRWM-------KAGMDLDDMDD 209

Query: 1341 KSASLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
                  + ++ +  ++  Y     +  G  D    VT+  +PS P  P +    SSS+ +
Sbjct: 210  LPIGRNVLQLRDIYESANYTCVATSLLGTIDTSARVTVRTRPSVPNSPVVTGYTSSSLTV 269

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDT----TEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455
             W       + T+  +V+EY+   +    TE + + +   T  +I+ L   + Y  R  A
Sbjct: 270  EW---STLSSDTVTSHVLEYKRSRSGGSFTE-MEIPSPQDTSFTIEGLLPYTEYAVRLLA 325

Query: 1456 VNEVDISDASE 1466
            VN +  S+ S+
Sbjct: 326  VNSIGRSNPSD 336



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 5/106 (4%)

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKP-NILE--IDSSSINICWDEP-ENTGNSTII 1413
            +KL   N  G+++  +      + +P G P N+    + SSSI++ WD P E   N  I+
Sbjct: 719  FKLTASNEEGNSNEAIFYYTTHEGTPSGSPMNVTASPLSSSSISVSWDPPLEEERNGLIL 778

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
             Y + Y        ++    T+T   + +L  N++Y     A   V
Sbjct: 779  KYTIRYYSSAMPTELT-NRTTETDIVLTSLVPNTAYSVEVRAHTSV 823


>UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger
            receptor cysteine-rich protein type 12 precursor; n=1;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            scavenger receptor cysteine-rich protein type 12
            precursor - Strongylocentrotus purpuratus
          Length = 2255

 Score =  112 bits (269), Expect = 1e-22
 Identities = 89/354 (25%), Positives = 164/354 (46%), Gaps = 27/354 (7%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI---AWLFKGEEIVPDENISVAI 684
            ++   PPTF+++PK + ++ GS  L  C+    P P +   +WL  G+ +   +  S  +
Sbjct: 1772 VVSSYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRL 1831

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744
               ++     L+    ++   G YT V  N +G  +    L +    KE P ++      
Sbjct: 1832 R--VYTSSGSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVV----KERPHIMSTHPDT 1885

Query: 745  IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
             +  GE+  L   VVG P  T++W +N +P+     +S G+  ++ +++  +++D G+Y 
Sbjct: 1886 RI-LGETAELGCIVVGLPESTVSWRRNGQPLMGERFQSFGENGTL-LIRDVRLEDNGMYE 1943

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A N  G  + S  +TV        E P F+   QE+ V+    + +   V+  P+P I
Sbjct: 1944 CVAVNQLGEDQASVKLTV-------YEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEI 1996

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TW ++ ++IS +  +T     E+  LVI     E D G+Y C+ASN    S+  A++ I 
Sbjct: 1997 TWKKDGQMISLNGRVTIL---EDNTLVIHKSQRE-DMGEYACIASNKVQTSARIAKLLI- 2051

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREII 976
                  +     +     G+TV+L C    ++     W HN +++   D R ++
Sbjct: 2052 -IGPPHITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVVN-DERHLM 2103



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 83/333 (24%), Positives = 135/333 (40%), Gaps = 26/333 (7%)

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
            + SS +   V     D G+   V              +++  P   S  P  + + E ++
Sbjct: 1834 YTSSGSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRILGETAE 1893

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
              L C +V +PE  ++W   G+ ++ +   S             L I +V+    G Y  
Sbjct: 1894 --LGCIVVGLPESTVSWRRNGQPLMGERFQSFGENG-------TLLIRDVRLEDNGMYEC 1944

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            VAVN+ GE    + L +     E P  +E  + M VR G  V +   V G P P ITW K
Sbjct: 1945 VAVNQLGEDQASVKLTVY----EVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKK 2000

Query: 771  NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            + + +      +  + +++ I K ++ +D G Y   A N    +   A + +  P     
Sbjct: 2001 DGQMISLNGRVTILEDNTLVIHKSQR-EDMGEYACIASNKVQTSARIAKLLIIGPPHITE 2059

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
             P    N+ + +T +   T+ L   V     P +TW  N E +   E      D     L
Sbjct: 2060 APT---NQTR-VTGE---TVVLPCTVIGAYNPVVTWQHNGEDVVNDERHLMVDDS----L 2108

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             +T+VD   D G Y C A+N+ G  S  A V+I
Sbjct: 2109 TVTDVDPA-DGGLYVCTATNTEGAVSANAYVSI 2140



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 45/190 (23%), Positives = 85/190 (44%), Gaps = 6/190 (3%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
            E  EL CI  G+P+  V+W R+G+ L   +  ++                  Y+C+A N 
Sbjct: 1890 ETAELGCIVVGLPESTVSWRRNGQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQ 1949

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             GE + S  + + + P      ++++   + G +  +  V+ G+P PE+ W K+G  +  
Sbjct: 1950 LGEDQASVKLTVYEVPTFLEGPQEMEV--RTGSDVSIPCVVSGVPLPEITWKKDGQMISL 2007

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
            +    +T  E  +++ I + +R    +Y   ASN   TS+    L +   P   E P   
Sbjct: 2008 NG--RVTILEDNTLV-IHKSQREDMGEYACIASNKVQTSARIAKLLIIGPPHITEAPTNQ 2064

Query: 1676 REISRESVTI 1685
              ++ E+V +
Sbjct: 2065 TRVTGETVVL 2074



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 62/236 (26%), Positives = 99/236 (41%), Gaps = 16/236 (6%)

Query: 591  FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650
            F  + T LI +  L D+G    V               +  +P TF + P+   V  GSD
Sbjct: 1923 FGENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTVYEVP-TFLEGPQEMEVRTGSD 1981

Query: 651  ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            + + C +  +P P+I W   G+ I    N  V I  D     + L I   ++   G Y  
Sbjct: 1982 VSIPCVVSGVPLPEITWKKDGQMI--SLNGRVTILED-----NTLVIHKSQREDMGEYAC 2034

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
            +A N+  + S  I   +  G   PP + E   +     GE+V+L   V+G   P +TW  
Sbjct: 2035 IASNKV-QTSARIAKLLIIG---PPHITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQH 2090

Query: 771  NNKP-VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            N +  V         D+ ++T + P    D G+Y   A N+EG    +A +++  P
Sbjct: 2091 NGEDVVNDERHLMVDDSLTVTDVDP---ADGGLYVCTATNTEGAVSANAYVSITGP 2143



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 69/309 (22%), Positives = 127/309 (41%), Gaps = 23/309 (7%)

Query: 1079 TSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
            T   D G Y+C++R+    + ++   VV+  P I++   + ++         I +   ++
Sbjct: 1845 TRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRILGETAELGCIVVGLPES 1904

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191
             V W ++G  +           G+   L I D  L+D G Y C    ++G  + +  LTV
Sbjct: 1905 TVSWRRNGQPLMGERFQSF---GENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTV 1961

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK 1250
             E  +   L  P+ + V   +D  +   +    L ++TW K   +I    + T++ D   
Sbjct: 1962 YE--VPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDGQMISLNGRVTILED--- 2016

Query: 1251 RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
             TL+I K   +D  EY C+  +  +++ ++   ++  PP I +         G  V L  
Sbjct: 2017 NTLVIHKSQREDMGEYACIASNKVQTSARIAKLLIIGPPHITEAPTNQTRVTGETVVLPC 2076

Query: 1310 DYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                   P   W  N + ++   +H    +D    SLT+  V+  D G+Y     N  G 
Sbjct: 2077 TVIGAYNPVVTWQHNGEDVVNDERHL--MVDD---SLTVTDVDPADGGLYVCTATNTEGA 2131

Query: 1369 ADVEMNVTI 1377
                  V+I
Sbjct: 2132 VSANAYVSI 2140



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 15/213 (7%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT---WYRDGKKLKTAKAT------YENR 1532
            PT  +  KN T          C   G P P+VT   W +DG+ L     +      Y + 
Sbjct: 1778 PTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVYTSS 1837

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                           Y C+  N  G   +S  + ++++P I  ++ D +    +G+   +
Sbjct: 1838 GSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRI---LGETAEL 1894

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
              ++ G+P   V W +NG  L  ++     +  +   + I++++   +  Y   A N  G
Sbjct: 1895 GCIVVGLPESTVSWRRNGQPLMGER---FQSFGENGTLLIRDVRLEDNGMYECVAVNQLG 1951

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
                 V L VY+ P+  EGP  M   +   V+I
Sbjct: 1952 EDQASVKLTVYEVPTFLEGPQEMEVRTGSDVSI 1984



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 21/227 (9%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I++++   +  +   AVN++    AS        +K T  + PT  +  + +      D+
Sbjct: 1931 IRDVRLEDNGMYECVAVNQLGEDQAS--------VKLTVYEVPTFLEGPQEMEVRTGSDV 1982

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
             + C+  GVP P++TW +DG+ +    + T                   Y CIA N   +
Sbjct: 1983 SIPCVVSGVPLPEITWKKDGQMISLNGRVTILEDNTLVIHKSQREDMGEYACIASN---K 2039

Query: 1559 VETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            V+TS  +    I   P IT       Q    G+  ++   + G   P V W  NG  + N
Sbjct: 2040 VQTSARIAKLLIIGPPHIT--EAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVVN 2097

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            D+ + +     T    + ++  +    Y   A+NT G  S    + +
Sbjct: 2098 DERHLMVDDSLT----VTDVDPADGGLYVCTATNTEGAVSANAYVSI 2140



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 20/205 (9%)

Query: 993  DVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048
            D G   C++++ +    +S  LVVKE  P  +    D  +  +   +  + +    + V 
Sbjct: 1849 DSGNYTCVIRNTQGVNTSSAFLVVKER-PHIMSTHPDTRILGETAELGCIVVGLPESTVS 1907

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVE 1104
            W R+G+ +  ++    F+  G    L IR+  + D G Y C+    L ++  + ++TV E
Sbjct: 1908 WRRNGQPLMGER----FQSFGENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTVYE 1963

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            + P  +   Q  +V  G+  +    +  G  L  + W KDG  I  +  + +  D     
Sbjct: 1964 V-PTFLEGPQEMEVRTGSDVSIPC-VVSGVPLPEITWKKDGQMISLNGRVTILED---NT 2018

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA 1187
            L I+    +D GEY+C   N   T+
Sbjct: 2019 LVIHKSQREDMGEYACIASNKVQTS 2043



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P F+E  +      GS V   C V G P P+ITW +   +I  S + ++   +DN  TLV
Sbjct: 1965 PTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDGQMI--SLNGRVTILEDN--TLV 2020

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I +   ED G + C+A N    ++   +L++  P
Sbjct: 2021 IHKSQREDMGEYACIASNKVQTSARIAKLLIIGP 2054



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T +  C V G P   ++W R    +   + FQ + ++    TL+IR+V  ED G + C
Sbjct: 1889 GETAELGCIVVGLPESTVSWRRNGQPLM-GERFQSFGEN---GTLLIRDVRLEDNGMYEC 1944

Query: 584  VAKNAAGFASSTTELIV-EAPLSDHG-SEMTV 613
            VA N  G   ++ +L V E P    G  EM V
Sbjct: 1945 VAVNQLGEDQASVKLTVYEVPTFLEGPQEMEV 1976



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 10/102 (9%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT---WFRQTAIIKP----SQDFQMY 559
            S  P F E+ + +    GS   F C+ +G P P++T   W +    +      S   ++Y
Sbjct: 1775 SYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVY 1834

Query: 560  YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
                ++  +  R    ED+G +TCV +N  G  +S+  L+V+
Sbjct: 1835 TSSGSLQFVRTRR---EDSGNYTCVIRNTQGVNTSSAFLVVK 1873



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G TV   C V G   P +TW      +  + +  +  DD    +L + +V P D G + C
Sbjct: 2069 GETVVLPCTVIGAYNPVVTWQHNGEDVV-NDERHLMVDD----SLTVTDVDPADGGLYVC 2123

Query: 584  VAKNAAGFASSTTELIVEAPL 604
             A N  G  S+   + +  P+
Sbjct: 2124 TATNTEGAVSANAYVSITGPV 2144


>UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep:
            Connectin/titin - Gallus gallus (Chicken)
          Length = 1021

 Score =  112 bits (269), Expect = 1e-22
 Identities = 182/774 (23%), Positives = 302/774 (39%), Gaps = 109/774 (14%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +P T   KP++  V EG      C +   P P I W+  G+ IV      +        Y
Sbjct: 326  LPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRAGQPIVSSRRFQIT----RTQY 381

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             S  +I+ V+   EG+YTVV  N EG       L ++   K  P              E 
Sbjct: 382  KSTFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQ--RKRIP--------------EK 425

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD-EGVYTLKAENS 810
             I S   + +P P +   K+ +PVK+                PK+VK  E + T     S
Sbjct: 426  AITSPPRIKSPEPRV---KSPEPVKS----------------PKRVKSPEPISTPSKAKS 466

Query: 811  EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
                +T+ V  V+ PT   A PP    + +  T+ +K  +      +   +  + WY++ 
Sbjct: 467  PPGDKTAPVEKVQLPT---ASPPKIKEQLKAETLGDKVKLSCAVESSVLSIREVAWYKDG 523

Query: 871  EIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
            + +        ++  +   EL I N+ +E D G+Y C      G S    + T  V K  
Sbjct: 524  KKLKEDHHFKFHYAADGTYELKIHNL-TESDKGEYTCEIMGEGGISKTNFQFTGQVFKNI 582

Query: 930  FVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
               H Q    +E  K+V  +      VST+    KK  +  + +  I+E           
Sbjct: 583  ---HSQVQSVSETPKSV-EKGDKVLAVSTQ----KKSSAATEEKAAIEE----------- 623

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049
                  VIK  +  ++      VK+   E         V E     L+  I    ++V W
Sbjct: 624  ------VIKKSIVTED------VKQLQAEIRASSTQMTVSEGQKVTLKANIPG-ASEVKW 670

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR-DE---SCTAEVTVVEL 1105
              +G  ++   + Y +   G    L I+  S  DEG  +C  + DE    C   +T  + 
Sbjct: 671  VLNGMELR-NSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEGTIKCQYVLTFSKE 729

Query: 1106 P---PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK 1160
            P   P  IT+ ++Q VN+G    F  E++ GD    V W ++   I  S+H++ T     
Sbjct: 730  PSNEPAFITQPKSQNVNEGQDVLFTCEVS-GDPSPEVEWLRNNQPIAVSSHMRATRSKNT 788

Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
              L+I +  + D G+Y+ +     G    TA LTV  P I      P+ +++  + DA +
Sbjct: 789  YSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTV-FPLIE---EPPKEVVLKTSGDASM 844

Query: 1217 TVEIPDETLDVTWYKKKSVIED------TE-KFTLISDVKKRTL---IIRKCTEDDQCEY 1266
                  ++  +   K+++          TE KF  +S     ++    +   +     + 
Sbjct: 845  HESFSSQSFQMAASKQEASFSSFSSSSMTETKFASMSAKSMSSMKESFVEMSSSSIMGKS 904

Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS- 1325
            +   L++ ++  LK  V   PPKI     +  I  G  +TL   +   P P   W     
Sbjct: 905  SMAQLESSTSKMLKSGVRGVPPKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGR 964

Query: 1326 KIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            KI  + +  +  I++     +L I  V+  D GIY L L N  G     +N+ I
Sbjct: 965  KITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLGNEFGTDSATVNINI 1018



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 66/318 (20%), Positives = 129/318 (40%), Gaps = 20/318 (6%)

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
            L   IP  + +V W      + +++ +         TL I+K +  D+   TC     + 
Sbjct: 658  LKANIPGAS-EVKWVLNGMELRNSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEG 716

Query: 1276 TTKLKVEVVEFP------PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            T K +  V+ F       P  +   +   +  G DV    +    P P  EW+ N++ I 
Sbjct: 717  TIKCQY-VLTFSKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIA 775

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
               H + +    + SL I+    +D G Y ++ +N  G      ++T+      P K  +
Sbjct: 776  VSSHMRATRSKNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIEEPPKEVV 835

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
            L+    +          + +S         QE   + + S  ++T+T+ +  + K+ SS 
Sbjct: 836  LKTSGDA------SMHESFSSQSFQMAASKQEASFSSF-SSSSMTETKFASMSAKSMSSM 888

Query: 1450 RFRAYAVNEVDISDASETTEY----YKVIKE-TKIQSPTVEKPLKNITTEPNEDIELTCI 1504
            +     ++   I   S   +      K++K   +   P +E    +I+ +  + + L+C 
Sbjct: 889  KESFVEMSSSSIMGKSSMAQLESSTSKMLKSGVRGVPPKIEALPSDISIDEGKVLTLSCA 948

Query: 1505 FGGVPQPKVTWYRDGKKL 1522
            F G P P++TWY  G+K+
Sbjct: 949  FSGEPAPEITWYCRGRKI 966



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 126/613 (20%), Positives = 220/613 (35%), Gaps = 48/613 (7%)

Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152
            E  T +   ++  P I  R+++ +V  G+   F + + +K  A V+W+ +G E+Q S+ I
Sbjct: 128  EVLTQQPFTLDHAPRITLRMRSHRVPCGHNTRFILNVQSKPTADVKWYHNGIELQESSKI 187

Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK--CTAILTVEEPSINFTLRLPE--FILV 1208
              +       L+I DC +DD+G Y     N K  C+   T++    ++T    +     V
Sbjct: 188  HFSNTSGVLTLEILDCHIDDSGTYRAVCTNYKGECSDYATLDVTGGDYTTYSSQRRDEEV 247

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYT 1267
            P +    LT     E   V+ +KK +  E +     + S+V      +         E  
Sbjct: 248  PRSILPDLT---RTEAYAVSSFKKATAAEASSSVREVKSEVSATRESLLSYEHHASSEEK 304

Query: 1268 CVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
                + KS  +  V        P  I+   R   +  G       D    P P   W+  
Sbjct: 305  ITASEEKSLEERTVHKAFKSTLPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRA 364

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK---- 1380
             + I   +  + +     ++  I  V+  D G Y + +EN+ G  +    +T+  K    
Sbjct: 365  GQPIVSSRRFQITRTQYKSTFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQRKRIPE 424

Query: 1381 ---PSPP----GKPNIL--EIDSSSINICWDEPENTGNSTII-----YYVVEYQEIDTTE 1426
                SPP     +P +   E   S   +   EP +T +            VE  ++ T  
Sbjct: 425  KAITSPPRIKSPEPRVKSPEPVKSPKRVKSPEPISTPSKAKSPPGDKTAPVEKVQLPTAS 484

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVE 1485
               +K   K +T    +K + +      ++ EV    D  +  E +   K       T E
Sbjct: 485  PPKIKEQLKAETLGDKVKLSCAVESSVLSIREVAWYKDGKKLKEDHH-FKFHYAADGTYE 543

Query: 1486 KPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544
              + N+T   ++  E TC I G     K  +   G+  K   +  ++             
Sbjct: 544  LKIHNLT--ESDKGEYTCEIMGEGGISKTNFQFTGQVFKNIHSQVQSVSETPKSVEKGDK 601

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEG----- 1598
                     +     E + +  + +K ++T   ED+KQ + ++        V EG     
Sbjct: 602  VLAVSTQKKSSAATEEKAAIEEVIKKSIVT---EDVKQLQAEIRASSTQMTVSEGQKVTL 658

Query: 1599 ---IP-PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
               IP   EV W  NG +L N  +Y          + IK+         T E     GT 
Sbjct: 659  KANIPGASEVKWVLNGMELRNSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEGTI 718

Query: 1655 SVEVTLKVYDKPS 1667
              +  L    +PS
Sbjct: 719  KCQYVLTFSKEPS 731



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 65/297 (21%), Positives = 117/297 (39%), Gaps = 11/297 (3%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            P F  +PK+Q V+EG D+L  C +   P P++ WL   + I    ++      + +    
Sbjct: 734  PAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIAVSSHMRATRSKNTYS--- 790

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
             L+I N      G YTV A N  G+ S    L +    +EPP+ +    S      ES  
Sbjct: 791  -LEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIEEPPKEVVLKTSGDASMHESFS 849

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
              +  +   +   ++   +         +     S++ +K   V +    ++  ++S   
Sbjct: 850  SQSFQMAASKQEASFSSFSSSSMTETKFASMSAKSMSSMKESFV-EMSSSSIMGKSSMAQ 908

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEI 872
             E+S    ++        PP       +I++ E   + L    +  P P ITWY R  +I
Sbjct: 909  LESSTSKMLKSGV--RGVPPKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGRKI 966

Query: 873  ISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
             S  +    + +  E++  +I     + D G Y     N  G  S  A V I++  +
Sbjct: 967  TSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLGNEFGTDS--ATVNINIRSI 1021



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+E S  P F+ + + ++  +G  V F C+V G P P++ W R    I  S   +     
Sbjct: 727 SKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIAVSSHMRA-TRS 785

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            N  +L IR     D G +T  AKN  G  S+T  L V
Sbjct: 786 KNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTV 823



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 2/129 (1%)

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            C    D G ++   V+   ++P        +   Q    G + L T  + G P PEV W 
Sbjct: 709  CEGKTDEGTIKCQYVLTFSKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWL 768

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            +N   +        T  + T  + I+    S + KYT++A N  G  S   +L V+    
Sbjct: 769  RNNQPIAVSSHMRATRSKNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIE 828

Query: 1668 KPEGPVIMR 1676
            +P   V+++
Sbjct: 829  EPPKEVVLK 837



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 4/157 (2%)

Query: 574  FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP 633
            F   + T T  A  +A   SS  E  VE   S    + ++            + +  G+P
Sbjct: 867  FSSSSMTETKFASMSAKSMSSMKESFVEMSSSSIMGKSSMAQLESSTSKMLKSGV-RGVP 925

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMHMYC 692
            P     P    +DEG  + L C     P P+I W  +G +I   D+     IE+   +  
Sbjct: 926  PKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDL-- 983

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
            + L I +V+K   G YT+   N  G  S  + + I++
Sbjct: 984  TTLIIMDVQKNDGGIYTLNLGNEFGTDSATVNINIRS 1020



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 1/97 (1%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           + ++    + K R     +G T +F C V+G P P ITW R    I  S+ FQ+      
Sbjct: 323 KSTLPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRAGQPIVSSRRFQITRTQYK 382

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
            +T  I  V   D G++T V +N+ G   +   L V+
Sbjct: 383 -STFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQ 418



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
            ++    G P PE+ WY  G K+ +  +   ++I T E  + + I +++++    YT+   
Sbjct: 945  LSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLG 1004

Query: 1649 NTAGTSSVEVTLKV 1662
            N  GT S  V + +
Sbjct: 1005 NEFGTDSATVNINI 1018



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 523  DGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580
            +G  +   C   G P P+ITW+ R   I    Q  + + +  +++ TL+I +V   D G 
Sbjct: 939  EGKVLTLSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGI 998

Query: 581  FTCVAKNAAGFASSTTELIVEA 602
            +T    N  G  S+T  + + +
Sbjct: 999  YTLNLGNEFGTDSATVNINIRS 1020


>UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|Rep:
           Peroxidasin precursor - Drosophila melanogaster (Fruit
           fly)
          Length = 1535

 Score =  112 bits (269), Expect = 1e-22
 Identities = 100/428 (23%), Positives = 172/428 (40%), Gaps = 31/428 (7%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+   +      G  V+  C+V G  RPQITW   T  +   +  Q         +L+
Sbjct: 238 PQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPS--GSLL 295

Query: 570 IREVFPEDAGTFTCVAKNAAG-FASSTTELIV-------EAPLSDHGSEMTVXXXX-XXX 620
            R     D G + C+A+N  G   S    L+V       ++P+    +++          
Sbjct: 296 HRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPTHG 355

Query: 621 XXXXXADILEGIPPTFSKKPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                +      PP F+ +P  Q V       +LL+C     P+PDI W   G +++   
Sbjct: 356 ATPLPSPSPSHSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLL-QS 414

Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
             S+ ++++       L +    +   GTY   A N  G       +++    KE P+++
Sbjct: 415 TPSLQLQAN-----GSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL----KELPEIL 465

Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV 797
              +S  ++ G++ +L     GNP PTI W  N  P+    P     + ++  ++   + 
Sbjct: 466 TAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQ 525

Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857
           +  GVY   A N  G  ETS   T++   E +  PP        +      TI+L  +  
Sbjct: 526 EHAGVYRCTAHNENG--ETSVEATIK--VERSQSPPQLAIEPSNLVAITGTTIELPCQAD 581

Query: 858 R-NPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKS 915
           +      I+W  +  +I P+  + + +       L + NV    D G Y+C   N  G++
Sbjct: 582 QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIP-DGGRYECQLKNQFGRA 640

Query: 916 SHGARVTI 923
           S  A VTI
Sbjct: 641 SASALVTI 648



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 5/172 (2%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            L C   G PQP + W+ +G++L   T     +                 Y+C A N  G 
Sbjct: 390  LDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGS 449

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
            V+ +  + +++ P I  + +   Q  K+G  +++    +G P P + W  NG  L  +  
Sbjct: 450  VQATARIELKELPEILTAPQS--QTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTP 507

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
                  E T ++ +   ++ H+  Y   A N  G +SVE T+KV    S P+
Sbjct: 508  DLQLENENTELV-VGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQ 558



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 63/295 (21%), Positives = 119/295 (40%), Gaps = 25/295 (8%)

Query: 832  PPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
            PP F ++   Q + +   G + L    +  P P I W+ N   +  S    Q     ++ 
Sbjct: 368  PPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLI 427

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            L+  N   ++ +G Y+C A NS G     AR  I+++++  +    +S   + GK  +LE
Sbjct: 428  LLQPN---QLSAGTYRCEARNSLGSVQATAR--IELKELPEILTAPQSQTIKLGKAFVLE 482

Query: 950  CQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--E 1005
            C        +  W  N   + G +  ++  E                GV +C   ++  E
Sbjct: 483  CDADGNPLPTIDWQLNGVPLPG-NTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGE 541

Query: 1006 TSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPK 1059
            TS    +K    ++ P+   +  +          L  + +   +   + W  DG +I P 
Sbjct: 542  TSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDGRLIDPN 601

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV---VELPP 1107
                +  +      L+++N ++ D G Y C L+++    S +A VT+   V+L P
Sbjct: 602  VQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLAP 656



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 14/190 (7%)

Query: 1226 DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVE 1282
            D+ W+   + +++ T    L ++    +LI+ +  +     Y C   ++  + +   ++E
Sbjct: 401  DIQWFVNGRQLLQSTPSLQLQAN---GSLILLQPNQLSAGTYRCEARNSLGSVQATARIE 457

Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            + E P +I+   +   IK G    L  D    P P  +W +N   +         +++++
Sbjct: 458  LKELP-EILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPG-NTPDLQLENEN 515

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG---KP-NILEIDSSSIN 1398
              L +       AG+Y+    N  G   VE  + +    SPP    +P N++ I  ++I 
Sbjct: 516  TELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIE 575

Query: 1399 I-CW-DEPEN 1406
            + C  D+PE+
Sbjct: 576  LPCQADQPED 585



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 56/253 (22%), Positives = 94/253 (37%), Gaps = 18/253 (7%)

Query: 1137 VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVEE 1193
            ++WF +G ++ Q +  +QL  +G    L +   +   AG Y CE  NS     A   +E 
Sbjct: 402  IQWFVNGRQLLQSTPSLQLQANGS---LILLQPNQLSAGTYRCEARNSLGSVQATARIEL 458

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
              +   L  P+   +       L  +     L    ++   V        L  + +   L
Sbjct: 459  KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTEL 518

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
            ++    ++    Y C   +    T     +KVE  + PP++           G+ + L  
Sbjct: 519  VVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIEL-- 576

Query: 1310 DYQAFPQPND----EWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLEN 1364
              QA  QP D     W  + ++I            S + SL +K V   D G Y+ +L+N
Sbjct: 577  PCQA-DQPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKN 635

Query: 1365 NCGHADVEMNVTI 1377
              G A     VTI
Sbjct: 636  QFGRASASALVTI 648


>UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone specific
            CMF608; n=2; Gallus gallus|Rep: PREDICTED: similar to
            bone specific CMF608 - Gallus gallus
          Length = 1817

 Score =  111 bits (267), Expect = 2e-22
 Identities = 203/942 (21%), Positives = 355/942 (37%), Gaps = 89/942 (9%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P     K  A  V   SD  + C     P+P I W     ++ PD +   +      +  
Sbjct: 845  PRIIGGKLAAFTVLANSDAFIPCEATGNPQPTIEWT----KMSPDTDAPASGSRWTVLPN 900

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I        G Y   A N  G A L   L +      PP++    + +    G  V
Sbjct: 901  GTLAIAQAALQDGGQYRCTATNVLGTARLLATLAVVA---YPPRIAGSTRLLTAHAGMPV 957

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT------ILKPKKVKDEGVYTLK 806
             +     G P P+I+W   N     + + S G+   +        +K   V D G+YT  
Sbjct: 958  AMRCPAEGRPPPSISWVLANGT--HVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCT 1015

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVPSIT 865
            A N  G   T A +TV+   +  A PP+ +  + Q+I       + L      NP P + 
Sbjct: 1016 ATNPAG---TDA-LTVK--LQVIAAPPIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVH 1069

Query: 866  WYRNN-EIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W  +    + P + + T+     N  L ++++    DSG+Y+C+A++S G       +T+
Sbjct: 1070 WVLSKGTAVKPLQFVNTRVLLLPNGTLQLSSI-VPADSGNYECIATSSTGSERRVVILTV 1128

Query: 924  DVEKV--TFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQ 977
                         Q   +   G  ++L C  +     +  W    K +    HR    I 
Sbjct: 1129 RHRDTLPRIAAASQGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIH 1188

Query: 978  EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE---VKEK 1031
                           D G   C+ +++    ++++K +I   P  I + Q F+      K
Sbjct: 1189 VYPNGSLVIEAVTEKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFKKLVPYGK 1248

Query: 1032 DVAILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGH------IRKLYIRNTSVHDE 1084
            D  +      S   ++ W   DG +I       D   R           LY+    V +E
Sbjct: 1249 DFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEE 1308

Query: 1085 GEYSCILRD----ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVR 1138
            G+Y+C  ++    +     VTVV   P+I    +   KV  G+ A  + E   +    + 
Sbjct: 1309 GDYTCYAQNSLGRDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIF 1368

Query: 1139 WFKDGSEIQFSN---HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAI-L 1189
            W    S+I  S+   H+ L ++G    L +    L DAGEY C   N     +K   + +
Sbjct: 1369 WLLPSSDIISSSTDRHL-LHVNG---SLSVRRAKLLDAGEYMCVARNAGGDDTKLYKLDV 1424

Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKF-TLI 1245
              + P IN        I V A   +   ++   E      + W    ++      + + I
Sbjct: 1425 DAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRI 1484

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF---PPKIVDYEREYRIK 1300
               K  TL IR     D  ++ CV  +   +S   +++EV+E    P     +  +   K
Sbjct: 1485 VIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAK 1544

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
             G  +TL       P P   W++ N   + K   T   +   + +L+I+      AG Y+
Sbjct: 1545 PGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYR 1604

Query: 1360 LRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSINICWDEPENTGNSTII-- 1413
               +N  G+ +  + + +  KP+    P G    +  +S S++   D       +  +  
Sbjct: 1605 CAAKNQVGYIEKLIVLEVAQKPTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPG 1664

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
             +V++  +I++   I ++N T        +    +Y  RA+        D S T     V
Sbjct: 1665 GHVLDRPQINSRH-ILLENGTLV-IRAATIHDRGNYVCRAHN----PAGDFSITIPVTIV 1718

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
                +I      +P + I T P   ++L+C   G+P+P++TW
Sbjct: 1719 AYPPRI----TNRPPQTIHTMPGAAVQLSCTALGIPRPEITW 1756



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 98/438 (22%), Positives = 175/438 (39%), Gaps = 32/438 (7%)

Query: 1252 TLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLL 1308
            TL + +    ++ +YTC   ++  +   K+ V VV   P+I   Y+   ++K G    L 
Sbjct: 1297 TLYLNRAGVTEEGDYTCYAQNSLGRDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLD 1356

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
             +    P+P   W++ S  I     T   +   + SL++++ +  DAG Y + +  N G 
Sbjct: 1357 CEAAGEPKPKIFWLLPSSDIISSS-TDRHLLHVNGSLSVRRAKLLDAGEY-MCVARNAGG 1414

Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE---------PENTGNSTIIYYVVEY 1419
             D ++    LD  + P   N L  + + I +              E T    I++ + + 
Sbjct: 1415 DDTKLYK--LDVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDN 1472

Query: 1420 QEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
              +    + S   I K  T  I+NL+ + +  F   A N+   S      E  ++++   
Sbjct: 1473 IFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPM 1532

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYE----NRX 1533
             ++P  EK    I  +P + I L C   G P P+V+W   +G  L     T E    +  
Sbjct: 1533 FKNPFNEK----IIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNG 1588

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y+C A N  G +E   V+ + QKP I +++     +   G+   + 
Sbjct: 1589 TLSIRNPSRDKAGKYRCAAKNQVGYIEKLIVLEVAQKPTI-LTHPKGPMRGISGESLSLH 1647

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYN---ITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
             + +G P P   W   G  + +  + N   I  +  T VIR   +       Y   A N 
Sbjct: 1648 CLSDGSPKPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATI--HDRGNYVCRAHNP 1705

Query: 1651 AGTSSVEVTLKVYDKPSK 1668
            AG  S+ + + +   P +
Sbjct: 1706 AGDFSITIPVTIVAYPPR 1723



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 99/430 (23%), Positives = 164/430 (38%), Gaps = 51/430 (11%)

Query: 510  PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVAT 567
            PI +E+ R +     G  +   C  EG P+P + W   +   +KP Q            T
Sbjct: 1036 PIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGT 1095

Query: 568  LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627
            L +  + P D+G + C+A ++ G   S   +++          +TV             D
Sbjct: 1096 LQLSSIVPADSGNYECIATSSTG---SERRVVI----------LTV----------RHRD 1132

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
             L  I        +  + D+   +LL C     P+P I W    + +V   +    + S 
Sbjct: 1133 TLPRIAAASQGMTQLSFGDK---LLLNCTATGEPQPRIMWRLPSKAVVDQWH---RMGSR 1186

Query: 688  MHMYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            +H+Y +  L I  V +   G Y  VA N+ G+    I++K+    K      +     +V
Sbjct: 1187 IHVYPNGSLVIEAVTEKDAGDYLCVARNKIGDDL--ILMKVSITMKPAKIDQKQYFKKLV 1244

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH----------SITILKPKK 796
              G+   +  +  G+P P I+W   +  V      +D   H              L    
Sbjct: 1245 PYGKDFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAG 1304

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
            V +EG YT  A+NS G  E    +TV       A P +  +    + VK   T  L    
Sbjct: 1305 VTEEGDYTCYAQNSLGRDEMKIHVTV-----VTAAPQIKHSYKTYVKVKAGDTALLDCEA 1359

Query: 857  TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
               P P I W   +  I  S T  ++    N  L +      +D+G+Y CVA N+ G  +
Sbjct: 1360 AGEPKPKIFWLLPSSDIISSST-DRHLLHVNGSLSVRRA-KLLDAGEYMCVARNAGGDDT 1417

Query: 917  HGARVTIDVE 926
               ++ +D +
Sbjct: 1418 KLYKLDVDAK 1427



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 93/399 (23%), Positives = 142/399 (35%), Gaps = 51/399 (12%)

Query: 525  STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
            S  Q +C+ EG P PQI W     I   +  +          TL IR + P D   F CV
Sbjct: 1449 SKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICV 1508

Query: 585  AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
            A+                  +D G  + V             ++LE +     K P  + 
Sbjct: 1509 AR------------------NDWGESVLVVRL----------EVLEMLRRPMFKNPFNEK 1540

Query: 645  V--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
            +    G  I L C +   P P+++W+      +     +       +     L I N  +
Sbjct: 1541 IIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSN---GTLSIRNPSR 1597

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
             + G Y   A N+ G     IVL++    ++P  +  P   M    GES+ L     G+P
Sbjct: 1598 DKAGKYRCAAKNQVGYIEKLIVLEVA---QKPTILTHPKGPMRGISGESLSLHCLSDGSP 1654

Query: 763  RPTITWCKNNKPVKALPTKSDGDT---HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            +P+  W      V   P  +       +   +++   + D G Y  +A N  G    +  
Sbjct: 1655 KPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIP 1714

Query: 820  ITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            +T+       A PP   NR  Q I       ++L       P P ITW   +  I  +  
Sbjct: 1715 VTIV------AYPPRITNRPPQTIHTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGN 1768

Query: 879  ITQNFDGENIE----LVITNVDSEIDSGDYKCVASNSAG 913
              +    E +     L I N     DSG YKC A N  G
Sbjct: 1769 HGRASGSELLHPQGTLRIQNPQPS-DSGTYKCTARNHLG 1806



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 129/649 (19%), Positives = 227/649 (34%), Gaps = 39/649 (6%)

Query: 1074 LYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129
            L I   ++ D G+Y C    +L      A + VV  PP I    +    + G        
Sbjct: 903  LAIAQAALQDGGQYRCTATNVLGTARLLATLAVVAYPPRIAGSTRLLTAHAGMPVAMRCP 962

Query: 1130 LT-KGDALVRW-FKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186
               +    + W   +G+ +  S+   Q  +      L I D  + D G Y+C   N   T
Sbjct: 963  AEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGT 1022

Query: 1187 AILTVE-----EPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTE 1240
              LTV+      P I    +  + I   A  D  L           V W   K       
Sbjct: 1023 DALTVKLQVIAAPPIILEEKRQQ-IAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPL 1081

Query: 1241 KF--TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPPKIVDYE 1294
            +F  T +  +   TL +      D   Y C+   +  + +    L V   +  P+I    
Sbjct: 1082 QFVNTRVLLLPNGTLQLSSIVPADSGNYECIATSSTGSERRVVILTVRHRDTLPRIAAAS 1141

Query: 1295 REY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVE 1351
            +   ++  G  + L       PQP   W + SK +    H   S      + SL I+ V 
Sbjct: 1142 QGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIHVYPNGSLVIEAVT 1201

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNS 1410
              DAG Y     N  G   + M V+I  KP+    K    ++     +   D   +   +
Sbjct: 1202 EKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFKKLVPYGKDFQVDCKASGSPA 1261

Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT-- 1468
              I + +    +     ++  +  + +  +      + Y  RA    E D +  ++ +  
Sbjct: 1262 PEISWSLPDGMVINNAMLADDSGHRARRYVL-FDNGTLYLNRAGVTEEGDYTCYAQNSLG 1320

Query: 1469 -EYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---K 1523
             +  K+       +P ++   K  +  +  +   L C   G P+PK+ W      +    
Sbjct: 1321 RDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIFWLLPSSDIISSS 1380

Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT---ISNEDI 1580
            T +                     Y C+A N  G+      + +  KP I     +N+ I
Sbjct: 1381 TDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGGDDTKLYKLDVDAKPPIINGLYTNKTI 1440

Query: 1581 KQKHKVG-DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRS 1638
             +   V   +  +    EG PPP+++W    N       Y +     K   + I+ L+ S
Sbjct: 1441 IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPS 1500

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKP--EGPVIMREISRESVTI 1685
             ++ +   A N  G S + V L+V +   +P  + P   + I++   TI
Sbjct: 1501 DTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAKPGKTI 1549



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 9/128 (7%)

Query: 476  DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
            +E +YT Y Q  L    D++ +     +    +   +   ++ K    G T   +C+  G
Sbjct: 1307 EEGDYTCYAQNSLGR--DEMKIHVTVVTAAPQIKHSYKTYVKVKA---GDTALLDCEAAG 1361

Query: 536  YPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
             P+P+I W   ++ II  S D  + + +    +L +R     DAG + CVA+NA G  + 
Sbjct: 1362 EPKPKIFWLLPSSDIISSSTDRHLLHVN---GSLSVRRAKLLDAGEYMCVARNAGGDDTK 1418

Query: 595  TTELIVEA 602
              +L V+A
Sbjct: 1419 LYKLDVDA 1426



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 44/196 (22%), Positives = 69/196 (35%), Gaps = 12/196 (6%)

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKATYENRXXXXXXXXXXX 1543
            L   T   N D  + C   G PQP + W +           ++ T               
Sbjct: 852  LAAFTVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLAIAQAALQ 911

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
                Y+C A N  G       + +   P     +  +   H  G    +    EG PPP 
Sbjct: 912  DGGQYRCTATNVLGTARLLATLAVVAYPPRIAGSTRLLTAH-AGMPVAMRCPAEGRPPPS 970

Query: 1604 VIWY-KNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            + W   NG  + +  + N     +    + IK++       YT  A+N AGT ++ V L+
Sbjct: 971  ISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGTDALTVKLQ 1030

Query: 1662 VYDKPSKPEGPVIMRE 1677
            V   P     P+I+ E
Sbjct: 1031 VIAAP-----PIILEE 1041



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 51/199 (25%), Positives = 74/199 (37%), Gaps = 18/199 (9%)

Query: 634  PTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PT    PK       G  + L C     P+P  AW   G  ++    I+      + +  
Sbjct: 1626 PTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGHVLDRPQIN---SRHILLEN 1682

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751
              L I        G Y   A N  G+ S+ I + I      PP++   P +++    G +
Sbjct: 1683 GTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVA---YPPRITNRPPQTIHTMPGAA 1739

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--------KVKDEGVY 803
            V LS   +G PRP ITW   +  +  L T + G      +L P+        +  D G Y
Sbjct: 1740 VQLSCTALGIPRPEITWELPDHSI--LSTGNHGRASGSELLHPQGTLRIQNPQPSDSGTY 1797

Query: 804  TLKAENSEGIAETSAVITV 822
               A N  G   T   I V
Sbjct: 1798 KCTARNHLGSDFTVTYIHV 1816



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 520  HTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPE 576
            HT  G+ VQ  C   G PRP+ITW     +I+      +    +      TL I+   P 
Sbjct: 1733 HTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGNHGRASGSELLHPQGTLRIQNPQPS 1792

Query: 577  DAGTFTCVAKNAAGFASSTTELIV 600
            D+GT+ C A+N  G   + T + V
Sbjct: 1793 DSGTYKCTARNHLGSDFTVTYIHV 1816



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 524  GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            G  V   C  EG P P I+W     T +   SQ  Q      +  TL I++V   D G +
Sbjct: 954  GMPVAMRCPAEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPD-GTLTIKDVTVYDRGLY 1012

Query: 582  TCVAKNAAGFASSTTEL-IVEAP 603
            TC A N AG  + T +L ++ AP
Sbjct: 1013 TCTATNPAGTDALTVKLQVIAAP 1035



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 19/68 (27%), Positives = 30/68 (44%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T+   C V+G P P+++W     +          +   +  TL IR    + AG + C
Sbjct: 1546 GKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRC 1605

Query: 584  VAKNAAGF 591
             AKN  G+
Sbjct: 1606 AAKNQVGY 1613



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 44/186 (23%), Positives = 75/186 (40%), Gaps = 12/186 (6%)

Query: 749 GESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVY 803
           G +V L  Q +G P P I W   +   V+A     DG    +      L+     D G+Y
Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGLY 583

Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
                N       +  ITV +P  E++     +N  Q ++      + L    T  P  +
Sbjct: 584 HCIGTNYNDADILTFRITVVDPYVEHSS----VNGAQ-LSAAVGSILDLPCTSTAVPDAA 638

Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++W     ++    ++      +N  L I  V +E DSG ++CVA++  G      +V +
Sbjct: 639 VSWVLPERVVL-HHSVRNRHIFDNGTLRIQGV-TERDSGYFRCVAASQYGVDLLVFQVLV 696

Query: 924 DVEKVT 929
             +K T
Sbjct: 697 RKDKST 702



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 30/113 (26%), Positives = 41/113 (36%), Gaps = 8/113 (7%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
            EK+  L V +KPT        I      P     G ++   C  +G P+P   W      
Sbjct: 1615 EKLIVLEVAQKPT--------ILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGH 1666

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            +         +      TLVIR     D G + C A N AG  S T  + + A
Sbjct: 1667 VLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVA 1719



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 6/90 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQ--TAIIKP--SQDFQMYYDDDNVATLVIREVFPEDAG 579
           G TVQ +CQ  G P P I W     + +  P  S+D ++        TL   + F  D G
Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTF--DTG 581

Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGS 609
            + C+  N       T  + V  P  +H S
Sbjct: 582 LYHCIGTNYNDADILTFRITVVDPYVEHSS 611


>UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,
            isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG8581-PA, isoform A - Tribolium castaneum
          Length = 1429

 Score =  111 bits (267), Expect = 2e-22
 Identities = 144/641 (22%), Positives = 257/641 (40%), Gaps = 52/641 (8%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I N+K   +  ++  A N  D  DAS T +        ++     +KP   I    N+DI
Sbjct: 265  ITNIKEEDAGTYQCRAANREDSLDASATIQ-------VQVPPRFRKKPQDKIENA-NKDI 316

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            EL C   G P+PK++W++DG+ +  +   Y+  N                ++C A N  G
Sbjct: 317  ELECSVYGNPEPKISWFKDGEAI-ISNDYYQIVNGHNLKIMGLMPSDSGIFQCFASNPAG 375

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
             ++ +  + +   P      +  K +    D+     +   + P       + +     +
Sbjct: 376  NIQAAASLKVLN-PGPKKRKKSKKNRDNPIDQMQSFTLFSHLKPDSSARLGDVDFGHFAR 434

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEA----------------SNTAGTSSVEVTLK 1661
              N      +S   I + +R+ SS  + E+                S+T+ T+   V   
Sbjct: 435  RKNFMQDSSSSSQTIYDPQRAFSSLKSSESYDNINLGDTQHAFFPPSSTSITAESSVAKT 494

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
                P  P+  +    +    VT+ W+ PL +    +  Y +   +  + RW +V +  R
Sbjct: 495  TEGFPGPPQD-LKAPIVKARFVTLSWRAPLVNSD-NIHTYTVYYRQEGSERW-RVQNTSR 551

Query: 1722 D-VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
              +E   I  L  +  Y FRV+A N VG   + ES  +  ++   V S            
Sbjct: 552  SRLEEINIAGLTPSKVYHFRVVAINSVGAGVSSESLTVTTQSEEHVASAPTHFVAYAT-S 610

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
              ++Y+ W P E   G+ I+ Y V   +     +           +  LS+ T Y   + 
Sbjct: 611  PRTIYLNWRPPETPNGN-ILRYMVYYMETSSSVEHNIDTTELKYHLVGLSVYTEYSVWVV 669

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESN-GGSPIT 1898
            A NE G      +D+KI   +TL+  PS+P + +  E TS +V ++W  P        IT
Sbjct: 670  AVNENGPGA--ATDEKIV--RTLSASPSEPPSNITLEPTSTTVIVRWEPPPPEYQNGVIT 725

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             Y ++++    K  T  VT   +   + + +++   E   ++ A N  G S PTE  +V 
Sbjct: 726  GYKLKYRKQGKKGVT--VTTSANERFYVLNDLERGAEYQVKLWAINVNGTSPPTEWITVE 783

Query: 1959 LEKH----ATVPSPPTAPLEIRMV--GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
              K+    + VP  P  PL + +V   SN +   W TP  +    +  Y +        M
Sbjct: 784  TYKNDLDESRVPDLP-GPLRVILVRPTSNKLYVLW-TPPSNQNIRVRNYILGWGKGIPDM 841

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
            + +  ++D  T  + I  L  N  Y++ + A N++G   P+
Sbjct: 842  YTQ--ELDEKTRSYLIDKLEANSEYVLSLRAANQMGPGPPV 880



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 149/685 (21%), Positives = 257/685 (37%), Gaps = 46/685 (6%)

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFG 1506
            +YR  A  +N   +S+ +  T      +E     PT + +P   +  E  +++ L C   
Sbjct: 172  AYRCNATGLNLYKLSNKATLTVSGDR-EEAHFVPPTFIARPKSAVVVE-GQNVSLDCAAN 229

Query: 1507 GVPQPKVTWYRDGKK-----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            G P P +TW +DG       L +  +   +                Y+C A N    ++ 
Sbjct: 230  GYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDA 289

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            S  + +Q  P      +D K ++   D  L  +V  G P P++ W+K+G  + ++  Y I
Sbjct: 290  SATIQVQVPPRFRKKPQD-KIENANKDIELECSVY-GNPEPKISWFKDGEAIISNDYYQI 347

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEGPVIM 1675
                    ++I  L  S S  +   ASN AG      +LKV +      K SK      +
Sbjct: 348  VNGHN---LKIMGLMPSDSGIFQCFASNPAGNIQAAASLKVLNPGPKKRKKSKKNRDNPI 404

Query: 1676 REISRESVTIEWKPPLDD--GGLELTKYAIEKH--EPDNNRWIKVADVDRDVETYCIQKL 1731
             ++   ++    KP      G ++   +A  K+  +  ++    + D  R   +    + 
Sbjct: 405  DQMQSFTLFSHLKPDSSARLGDVDFGHFARRKNFMQDSSSSSQTIYDPQRAFSSLKSSES 464

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
             +N        A  P   S ++ +E  V KT    P           +    V ++W   
Sbjct: 465  YDNINLGDTQHAFFPPS-STSITAESSVAKTTEGFPG-PPQDLKAPIVKARFVTLSWRAP 522

Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTS 1848
              N  + I  Y V  +QEG ++W+           I    L+ +  Y FR+ A N +G  
Sbjct: 523  LVNSDN-IHTYTVYYRQEGSERWRVQNTSRSRLEEINIAGLTPSKVYHFRVVAINSVGAG 581

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
            +  +    +T        S P +FV   ++ R++ L W  PE+  G+ I  Y++ +    
Sbjct: 582  VS-SESLTVTTQSEEHVASAPTHFVAYATSPRTIYLNWRPPETPNGN-ILRYMVYYMETS 639

Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
                  I T     H   +  +    E    + A N  G    T+ + VR    +  PS 
Sbjct: 640  SSVEHNIDTTELKYH---LVGLSVYTEYSVWVVAVNENGPGAATDEKIVR--TLSASPSE 694

Query: 1969 PTAPLEIRMVGSNIVMTSW--GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026
            P + + +    S  V+  W    PE+  G  + GY +  R   K   + V     N   +
Sbjct: 695  PPSNITLEPT-STTVIVRWEPPPPEYQNGV-ITGYKLKYRKQGK-KGVTV-TTSANERFY 750

Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLE--SDEPFKVIPGEGSHADEEPGEQTEVXXXXX 2084
             + DL     Y ++++A N  G S P E  + E +K    E S   + PG    V     
Sbjct: 751  VLNDLERGAEYQVKLWAINVNGTSPPTEWITVETYKNDLDE-SRVPDLPG-PLRVILVRP 808

Query: 2085 XXXXXXXXWLREHNMDADIRSYARG 2109
                    W    N +  +R+Y  G
Sbjct: 809  TSNKLYVLWTPPSNQNIRVRNYILG 833



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 82/297 (27%), Positives = 128/297 (43%), Gaps = 27/297 (9%)

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           F ++P+   V EG      C +VA P   I WL K E  +  + + + +     +    L
Sbjct: 107 FLEEPRDLRVYEGQRAHFACHVVAAPPAKIRWL-KDERPLQIDELRMTL-----LPSGAL 160

Query: 696 KITNVKKFQEGTYTVVAV-----NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
           +I  V +  +G Y   A          +A+L +    +     PP  I   KS +V +G+
Sbjct: 161 EIDEVAESDQGAYRCNATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQ 220

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLK 806
           +V L     G P P+ITW K+   +      S     G T S+ I   K+ +D G Y  +
Sbjct: 221 NVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKE-EDAGTYQCR 279

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
           A N E   + SA I V+        PP F  + Q+        I+L   V  NP P I+W
Sbjct: 280 AANREDSLDASATIQVQ-------VPPRFRKKPQDKIENANKDIELECSVYGNPEPKISW 332

Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           +++ E I  S    Q  +G N++++        DSG ++C ASN AG     A + +
Sbjct: 333 FKDGEAII-SNDYYQIVNGHNLKIMGL---MPSDSGIFQCFASNPAGNIQAAASLKV 385



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 81/314 (25%), Positives = 128/314 (40%), Gaps = 32/314 (10%)

Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           F+E+ R     +G    F C V   P  +I W +     +P Q  ++         L I 
Sbjct: 107 FLEEPRDLRVYEGQRAHFACHVVAAPPAKIRWLKDE---RPLQIDELRMTLLPSGALEID 163

Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631
           EV   D G + C   NA G   +  +L  +A L+  G                       
Sbjct: 164 EVAESDQGAYRC---NATGL--NLYKLSNKATLTVSGDREEAHF---------------- 202

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           +PPTF  +PK+  V EG ++ L+C     P P I WL  G  I  D     +  S +   
Sbjct: 203 VPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTI--DMTFLDSRFSKVGS- 259

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            S L+ITN+K+   GTY   A NRE        ++++     PP+  +  +  I    + 
Sbjct: 260 TSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQV----PPRFRKKPQDKIENANKD 315

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           + L   V GNP P I+W K+ + + +       + H++ I+      D G++   A N  
Sbjct: 316 IELECSVYGNPEPKISWFKDGEAIISNDYYQIVNGHNLKIM-GLMPSDSGIFQCFASNPA 374

Query: 812 GIAETSAVITVEEP 825
           G  + +A + V  P
Sbjct: 375 GNIQAAASLKVLNP 388



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 62/245 (25%), Positives = 96/245 (39%), Gaps = 10/245 (4%)

Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797
           +E  + + V +G+    +  VV  P   I W K+ +P++    +          +     
Sbjct: 108 LEEPRDLRVYEGQRAHFACHVVAAPPAKIRWLKDERPLQIDELRMTLLPSGALEIDEVAE 167

Query: 798 KDEGVYTLKAENSEGIA-ETSAVITVEEPTEE-NAEPPLFINRFQEITVKEKGTIKLVAR 855
            D+G Y   A           A +TV    EE +  PP FI R +   V E   + L   
Sbjct: 168 SDQGAYRCNATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCA 227

Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDSEIDSGDYKCVASNSAG 913
               P PSITW ++   I  +  +   F   G    L ITN+  E D+G Y+C A+N   
Sbjct: 228 ANGYPHPSITWLKDGSTIDMT-FLDSRFSKVGSTSSLRITNIKEE-DAGTYQCRAANRED 285

Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMD 971
                A + + V    F K  Q   E    K + LEC        K  W+ + + I   D
Sbjct: 286 SLDASATIQVQVPP-RFRKKPQDKIE-NANKDIELECSVYGNPEPKISWFKDGEAIISND 343

Query: 972 HREII 976
           + +I+
Sbjct: 344 YYQIV 348



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 16/189 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P FI + +   V E     L+   N      + W +DG  I        F K G    L 
Sbjct: 205  PTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLR 264

Query: 1076 IRNTSVHDEGEYSC--ILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELT- 1131
            I N    D G Y C    R++S  A  T+ V++PP    + Q+ K+   NK   E+E + 
Sbjct: 265  ITNIKEEDAGTYQCRAANREDSLDASATIQVQVPPRFRKKPQD-KIENANK-DIELECSV 322

Query: 1132 --KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185
                +  + WFKDG  I  +++ Q+ ++G    LKI      D+G + C      GN + 
Sbjct: 323  YGNPEPKISWFKDGEAIISNDYYQI-VNG--HNLKIMGLMPSDSGIFQCFASNPAGNIQA 379

Query: 1186 TAILTVEEP 1194
             A L V  P
Sbjct: 380  AASLKVLNP 388



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 26/100 (26%), Positives = 45/100 (45%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           E   + P F+ + +     +G  V  +C   GYP P ITW +  + I  +     +    
Sbjct: 199 EAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVG 258

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           + ++L I  +  EDAGT+ C A N      ++  + V+ P
Sbjct: 259 STSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQVP 298



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 35/95 (36%), Positives = 45/95 (47%), Gaps = 6/95 (6%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATL 568
           P F +K + K       ++ EC V G P P+I+WF+   AII  S D   YY   N   L
Sbjct: 299 PRFRKKPQDKIENANKDIELECSVYGNPEPKISWFKDGEAII--SND---YYQIVNGHNL 353

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I  + P D+G F C A N AG   +   L V  P
Sbjct: 354 KIMGLMPSDSGIFQCFASNPAGNIQAAASLKVLNP 388



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 9/142 (6%)

Query: 1363 ENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIYYVVEYQ 1420
            EN  G A  E  V T+   PS P     LE  S+++ + W+  P    N  I  Y ++Y+
Sbjct: 673  ENGPGAATDEKIVRTLSASPSEPPSNITLEPTSTTVIVRWEPPPPEYQNGVITGYKLKYR 732

Query: 1421 EIDTTEWISVKNITKTQTSIQN-LKTNSSYRFRAYAVNEVDISDASE--TTEYYK-VIKE 1476
            +    + ++V      +  + N L+  + Y+ + +A+N    S  +E  T E YK  + E
Sbjct: 733  K-QGKKGVTVTTSANERFYVLNDLERGAEYQVKLWAINVNGTSPPTEWITVETYKNDLDE 791

Query: 1477 TKIQSPTVEKPLKNITTEPNED 1498
            +++  P +  PL+ I   P  +
Sbjct: 792  SRV--PDLPGPLRVILVRPTSN 811



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 13/126 (10%)

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKPNILE----- 1391
            +D K+ S  I K+E     +  LR  N  G    V   V   D+P P   P ++      
Sbjct: 846  LDEKTRSYLIDKLEANSEYVLSLRAANQMGPGPPVYTTVRTQDEPPPEPSPPLIPPVGLK 905

Query: 1392 ---IDSSSINICWDEPENTGNSTI---IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
               + ++S+ + W +   + +  +    YYVV+Y    T    +V N++     I +LK 
Sbjct: 906  AQILSATSVVLYWTDTTLSKSQFVRDNRYYVVKYTAERTMRTRTV-NVSDLNVMIDDLKP 964

Query: 1446 NSSYRF 1451
            N+ Y F
Sbjct: 965  NTLYEF 970



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 39/173 (22%), Positives = 67/173 (38%), Gaps = 15/173 (8%)

Query: 1227 VTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-------VLLDAKSTTK 1278
            + W K +  ++ D  + TL+       L I +  E DQ  Y C         L  K+T  
Sbjct: 136  IRWLKDERPLQIDELRMTLLPS---GALEIDEVAESDQGAYRCNATGLNLYKLSNKATLT 192

Query: 1279 LKVEVVE---FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHT 1334
            +  +  E    PP  +   +   +  G +V+L      +P P+  W+ +   I      +
Sbjct: 193  VSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDS 252

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            + S    ++SL I  ++  DAG Y+ R  N     D    + +   P    KP
Sbjct: 253  RFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQVPPRFRKKP 305


>UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphatase S
            precursor; n=34; Craniata|Rep: Receptor-type
            tyrosine-protein phosphatase S precursor - Homo sapiens
            (Human)
          Length = 1948

 Score =  111 bits (266), Expect = 3e-22
 Identities = 132/604 (21%), Positives = 232/604 (38%), Gaps = 52/604 (8%)

Query: 1473 VIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----------GK 1520
            V++E ++ S  P ++   +    E      + C   G P P++TW++D          G+
Sbjct: 124  VLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183

Query: 1521 KLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVI 1573
              +    T+E+   R               Y+C+A N  G   +S     V  +++   +
Sbjct: 184  IKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRV 243

Query: 1574 TISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
                  +   H++  G    +T V  G P P V W +    L  + +  +      +V+ 
Sbjct: 244  APRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLE 299

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            + ++K   S+ YT  A ++ G       + V   P  P  P++  E +  S+TI W    
Sbjct: 300  LTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMV-TENTATSITITW---- 352

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            D G  +   Y + +++  +         D     Y I  L+ N EY   V A N +G  +
Sbjct: 353  DSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG--Q 410

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNG--GSPIIDYKVEIKQ 1808
               SE +V +T    P+          +   ++ + W  P E NG      + Y +E + 
Sbjct: 411  GPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEH 470

Query: 1809 EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
                W+           +  L  + TY  R+ A   +G   P +  D I +      P Q
Sbjct: 471  PVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDG-PLS--DPIQVKTQQGVPGQ 527

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
            P N      +  S+TL W+ P       I  Y + F+  +G    ++         + +E
Sbjct: 528  PMNLRAEARSETSITLSWSPPRQES---IIKYELLFR--EGDHGREVGRTFDPTTSYVVE 582

Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW- 1987
            ++K   E  FR++A +  G+   T    VR     + PS P   ++   V S  ++ SW 
Sbjct: 583  DLKPNTEYAFRLAARSPQGLGAFT--PVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWR 640

Query: 1988 -GTPEWDGGAPLLGYNIAIRDV--TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
               PE   GA L+GY++  R +        EV  +   T +  +  L +   Y I   A 
Sbjct: 641  PPPPETHNGA-LVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAH 699

Query: 2045 NEIG 2048
             E+G
Sbjct: 700  TEVG 703



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 153/740 (20%), Positives = 282/740 (38%), Gaps = 59/740 (7%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343
            E PP+ +   ++     G   + +      P+P   W    K +   +      D S  A
Sbjct: 30   EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGA 89

Query: 1344 SLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNI--------LEID 1393
             L I+ +    D  +Y+   +N+ G   V   +T+L +   P G PNI        +E  
Sbjct: 90   VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERT 149

Query: 1394 SSSINICWDEPENTGN-STIIYYVVEYQEIDTT----EWISVKNITKTQTSIQN-LKTNS 1447
             ++  +C      +GN    I +  ++  +D +        +++ T   T I+  L+  S
Sbjct: 150  RTATMLC----AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIES 205

Query: 1448 SY-----RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502
            S      ++   A N   +  +S    Y + ++E +  +P       +    P  ++ +T
Sbjct: 206  SEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNIT 265

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            C+  G P P V W +  + L         R               Y C+A +  G +E  
Sbjct: 266  CVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSAN--YTCVAMSSLGVIEAV 323

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNI 1621
              + ++  P        + +         +T   +   P  V +Y    K ++ D  Y I
Sbjct: 324  AQITVKSLPKAP-GTPMVTENTATS----ITITWDSGNPDPVSYYVIEYKSKSQDGPYQI 378

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREI 1678
                 T+   I  L  +   +  + A N+ G    S   VT      P+     V  R +
Sbjct: 379  KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARML 438

Query: 1679 SRESVTIEWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
            S  ++ ++W+ P++  GL       Y +E   P  N W K  +VD  + T  +  L E+ 
Sbjct: 439  SATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGN-WQK-HNVDDSLLT-TVGSLLEDE 495

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
             Y  RV+A   VG  +   S+PI +KT   VP            +  S+ ++W P  +  
Sbjct: 496  TYTVRVLAFTSVG--DGPLSDPIQVKTQQGVPGQPMNLRAEARSET-SITLSWSPPRQES 552

Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTS 1853
               II Y++ + +EG   +             ++ L  NT Y FR+ AR+  G       
Sbjct: 553  ---IIKYEL-LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPV 608

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
              + T+    + P Q    V   ST+  V+ +   PE++ G+ +  Y + ++ + G    
Sbjct: 609  VRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGA-LVGYSVRYRPL-GSEDP 666

Query: 1914 KIVTVGG---SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
            +   V G   +  +  +E +++  +  +RI+      V    ES  V +     VPS P 
Sbjct: 667  EPKEVNGIPPTTTQILLEALEKWTQ--YRITTVAHTEVGPGPESSPVVVRTDEDVPSAPP 724

Query: 1971 APLEIRMVGSNIVMTSWGTP 1990
              +E   + +  +   W +P
Sbjct: 725  RKVEAEALNATAIRVLWRSP 744



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 157/757 (20%), Positives = 287/757 (37%), Gaps = 71/757 (9%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161
            E PP  I   ++Q    G  A+F  + T GD   R  W K G ++       +  D    
Sbjct: 30   EEPPRFIKEPKDQIGVSGGVASFVCQAT-GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88

Query: 1162 K-LKIYDCDLD-DAGEYSCEVGNS--------KCTAILTVEEPSINFTLRL-PEFILVP- 1209
              L+I       D   Y C   NS        K T +   + PS    + + P+  +V  
Sbjct: 89   AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT---------LIIRKCTE 1260
              T   L     +   ++TW+K    ++ +     I  ++  T         L I    E
Sbjct: 149  TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEE 208

Query: 1261 DDQCEYTCVLLDA-----KSTTKLKV----EVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
             DQ +Y CV  ++      S   L V    EV    P+       + I  G +V +    
Sbjct: 209  TDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVA 268

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
               P P  +W+  ++ +       P  D       ++  +  D+  Y     ++ G  + 
Sbjct: 269  VGSPMPYVKWMQGAEDLT------PEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEA 322

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISV 1430
               +T+   P  PG P + E  ++SI I WD    +GN   + YYV+EY+         +
Sbjct: 323  VAQITVKSLPKAPGTPMVTENTATSITITWD----SGNPDPVSYYVIEYKSKSQDGPYQI 378

Query: 1431 K-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP-TVEKPL 1488
            K +IT T+ SI  L  NS Y     AVN +     SE+    +  ++    +P  V+  +
Sbjct: 379  KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV-VTRTGEQAPASAPRNVQARM 437

Query: 1489 KNITT---EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
             + TT   +  E +E   +  G  +   T   +       K   ++              
Sbjct: 438  LSATTMIVQWEEPVEPNGLIRGY-RVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDET 496

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-- 1603
               + +AF   G+   S    IQ K    +  + +  + +   E  +T  +   PP +  
Sbjct: 497  YTVRVLAFTSVGDGPLS--DPIQVKTQQGVPGQPMNLRAEARSETSIT--LSWSPPRQES 552

Query: 1604 VIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK- 1661
            +I Y+    + ++ +E   T    TS + +++LK +    + + A +  G  +    ++ 
Sbjct: 553  IIKYELLFREGDHGREVGRTFDPTTSYV-VEDLKPNTEYAFRLAARSPQGLGAFTPVVRQ 611

Query: 1662 --VYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEP---DNNRWIK 1715
              +  KPS P   V    +   ++ + W+ PP +     L  Y++ ++ P   ++    +
Sbjct: 612  RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSV-RYRPLGSEDPEPKE 670

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
            V  +        ++ L +  +Y    +A   VG     ES P+V++T  DVPS       
Sbjct: 671  VNGIPPTTTQILLEALEKWTQYRITTVAHTEVG--PGPESSPVVVRTDEDVPSAPPRKVE 728

Query: 1776 XXXIDNESVYITW-FPSEKNGGSPIIDYKVE-IKQEG 1810
               ++  ++ + W  P+       I  Y+V  ++ EG
Sbjct: 729  AEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEG 765



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 81/309 (26%), Positives = 134/309 (43%), Gaps = 30/309 (9%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F K+PK Q    G      C+    P+P + W  KG+++  +      IE D     
Sbjct: 32  PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV--NSQRFETIEFD-ESAG 88

Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748
           +VL+I  ++    E  Y  VA N  GE ++   L +   ++ P   P +    +  +V +
Sbjct: 89  AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-------DTHSITILK------PK 795
             +  +     GNP P ITW K+  PV   P+ S+G       +T   T ++        
Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVD--PSASNGRIKQLRSETFESTPIRGALQIESS 206

Query: 796 KVKDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
           +  D+G Y   A NS G+  +S A + V E  E     P F        +   G + +  
Sbjct: 207 EETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITC 266

Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
               +P+P + W +  E ++P + +     G N+ L +T+V    DS +Y CVA +S G 
Sbjct: 267 VAVGSPMPYVKWMQGAEDLTPEDDMPV---GRNV-LELTDVK---DSANYTCVAMSSLGV 319

Query: 915 SSHGARVTI 923
               A++T+
Sbjct: 320 IEAVAQITV 328



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 73/276 (26%), Positives = 120/276 (43%), Gaps = 21/276 (7%)

Query: 717 GEASLPIVLKIK-TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
           G   L +VL +     +EPP+ I+  K  I   G       Q  G+P+P +TW K  K V
Sbjct: 14  GPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 73

Query: 776 KALPTKS---DGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            +   ++   D    ++  ++P +  +DE VY   A+NS G     A +TV    +  + 
Sbjct: 74  NSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-------ETITQNFD 884
            P      Q   V+   T  ++   + NP P ITW+++   + PS       +  ++ F+
Sbjct: 134 FPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFE 193

Query: 885 GENIELVITNVDS-EIDSGDYKCVASNSAG-KSSHGARVTI----DVEKVT-FVKHLQKS 937
              I   +    S E D G Y+CVA+NSAG + S  A + +    +V +V      L  S
Sbjct: 194 STPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMS 253

Query: 938 YETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971
           +E   G  V + C    S     KW    ++++  D
Sbjct: 254 HEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED 289



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 80/346 (23%), Positives = 140/346 (40%), Gaps = 39/346 (11%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++ + +    G    F CQ  G P+P++TW ++   +   +   + +D+   A L 
Sbjct: 33  PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92

Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
           I+ +  P D   + CVA+N+ G      E+ V A L+                     D 
Sbjct: 93  IQPLRTPRDENVYECVAQNSVG------EITVHAKLT-----------------VLREDQ 129

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           L    P     P+ + V+      + C     P+P+I W      + P  +     +   
Sbjct: 130 LPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRS 189

Query: 689 HMYCSV-----LKITNVKKFQEGTYTVVAVNREG-EASLPI---VLKIKTGEKEPPQV-I 738
             + S      L+I + ++  +G Y  VA N  G   S P    V +++   +  P+  I
Sbjct: 190 ETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSI 249

Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798
            P+   I+  G +V ++   VG+P P + W +  + +    T  D       +L+   VK
Sbjct: 250 LPMSHEIM-PGGNVNITCVAVGSPMPYVKWMQGAEDL----TPEDDMPVGRNVLELTDVK 304

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
           D   YT  A +S G+ E  A ITV+   +    P +  N    IT+
Sbjct: 305 DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITI 350



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 83/433 (19%), Positives = 164/433 (37%), Gaps = 38/433 (8%)

Query: 1643 YTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE--SVTIEWKPPLDDGGLEL 1698
            YT+   A  + G   +   ++V  +   P  P+ +R  +R   S+T+ W PP  +    +
Sbjct: 497  YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES---I 553

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
             KY +   E D+ R  +V        +Y ++ L  N EY FR+ A++P G        P+
Sbjct: 554  IKYELLFREGDHGR--EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLG---AFTPV 608

Query: 1759 V-IKTALDVPSXXXXXXXXXXIDNESVYITWF--PSEKNGGSPIIDYKVEIKQEGK---- 1811
            V  +T    PS          + + ++ ++W   P E + G+ ++ Y V  +  G     
Sbjct: 609  VRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGA-LVGYSVRYRPLGSEDPE 667

Query: 1812 -KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870
             K             ++ L   T Y+    A  E+G   P +S   +   + + P + PR
Sbjct: 668  PKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPG-PESSPVVVRTDEDV-PSAPPR 725

Query: 1871 NFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEFKTVKG---KSWTKIVTVGGSVHEHC 1926
                    + ++ + W  P        I  Y + +  ++G   +   +I  V  +  +  
Sbjct: 726  KVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWE 785

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPT---ESQSVRLEKHATVPSPPT---APLEIRMVGS 1980
             ++  E + +I  +  E    +++     +    R +    V          L ++    
Sbjct: 786  TDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPE 845

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAI--RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
              ++  W  P       +LGY +     D T    +E    +    ++    + +  TY+
Sbjct: 846  GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSED---RYTASGVHKGATYV 902

Query: 2039 IRIYARNEIGLSE 2051
             R+ AR+  GL E
Sbjct: 903  FRLAARSRGGLGE 915



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 56/252 (22%), Positives = 96/252 (38%), Gaps = 27/252 (10%)

Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741
            S+   W+PP      ++  Y ++    D+   +   +     + Y    +++   Y+FR+
Sbjct: 847  SLLARWEPPAGTAEDQVLGYRLQFGREDSTP-LATLEFPPSEDRYTASGVHKGATYVFRL 905

Query: 1742 IAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGS 1797
             A++  G  E A E   I   T    P               +V + W P   +E+NG  
Sbjct: 906  AARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASA---GTVLLRWLPPVPAERNGA- 961

Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXAR--------IQKLSINTTYQFRIYARNEIGTSL 1849
             I+ Y V +++ G             A         +Q L  +T Y  ++ A    G   
Sbjct: 962  -IVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPG- 1019

Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK---- 1905
            P++    +     L     P+NF V      SV L W  P+ N  SP T Y I++     
Sbjct: 1020 PFSPP--VRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPD-NYNSP-TPYKIQYNGLTL 1075

Query: 1906 TVKGKSWTKIVT 1917
             V G++  K++T
Sbjct: 1076 DVDGRTTKKLIT 1087


>UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n=1;
            Danio rerio|Rep: PREDICTED: similar to adlican - Danio
            rerio
          Length = 1903

 Score =  110 bits (265), Expect = 4e-22
 Identities = 193/925 (20%), Positives = 354/925 (38%), Gaps = 92/925 (9%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDD 563
            Q  A I  +KL       G+ VQ  C   G PRP +TW + +  A++  +   Q +    
Sbjct: 926  QMRARITDDKLHTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHP 985

Query: 564  NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
            N  T  IR V  +D G + C A NA                  HG++  +          
Sbjct: 986  N-GTFTIRNVHLQDRGQYLCSASNA------------------HGTDKMMVTLV------ 1020

Query: 624  XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                +L  +P   S + +   V  G+  LL+C+   +P P+I+W+     ++   ++S  
Sbjct: 1021 ----VLAHVPRMTSPRHQDVTVYIGNTALLQCQAQGLPIPNISWMLPDRSML--RSVSNT 1074

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
             +  M +    L+I        G Y  +A N  G   L + L+I      P    +  ++
Sbjct: 1075 QQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSVRLQITA--LAPVIQEQRWEN 1132

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKD 799
              +  G + ++     G P PT+ W  ++    +P + + +      +    ++   VKD
Sbjct: 1133 YTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQFVNSNLFVFPNGTLFIRNPTVKD 1192

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             G+Y   A +S G+A+ S  + V+     +    +         V     + L    + +
Sbjct: 1193 SGIYECVAVSSVGMAKRSVNLQVK---RNSGSARILSTSAHSTDVHYGDQLSLNCSASGS 1249

Query: 860  PVPSITWYR-NNEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
            P P I W     +++    +  +      N  L IT+V +E D G+Y C A N+AG    
Sbjct: 1250 PTPRIIWRTPAKKLVDSYYSFDRRMKVLSNGTLTITSV-TEQDEGEYLCAARNNAGDDYV 1308

Query: 918  GARVTIDVEKVTFVKHLQKS-YETEEGKTVILECQTS--HTVSTKW-YHNKKEISGM--D 971
              +VT+ + K   + H   S ++   G  + ++C  S        W   +   I+ +   
Sbjct: 1309 LLKVTV-MMKAAKIDHKSLSEHKVLYGGELKVDCIASGLPNPEVSWSLPDGTMINSVLSS 1367

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGV-----IKCIVKDQ----ETSTMLVVKETIPEFIRK 1022
             +  I+  R            +VG+       C  K+Q    E    + V    P     
Sbjct: 1368 DKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNN 1427

Query: 1023 LQD-FEVKEKDVAILEVEINSETADVV-W-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
                 +V   + AIL      E   V+ W   D ++I P  NKY     G    L+I  T
Sbjct: 1428 AYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDG---TLHIHKT 1484

Query: 1080 SVHDEGEYSCILRD-ESCTAEVTVVELP--PEIITRLQN-----QKVNKGNKATFEIELT 1131
               + G Y+C+ R       +V +VE+   P +I   ++     +   +  +  F+ +  
Sbjct: 1485 QKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFEHPGIIRKTAVRDQRVLFDCK-A 1543

Query: 1132 KGDALVR--WFKDGSEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183
             G+   R  W    + +  + +   ++T+  +   L I+   + D+ E  C    E G +
Sbjct: 1544 NGNPFPRIIWLFPNNVVLPAPYYGSRITVH-RNGTLDIHAVRMSDSVELICIARNEFGET 1602

Query: 1184 KCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIP-DETLDVTW-YKKKSVIEDT 1239
            K    L V E  I   LR    + I +       L   I  +    +TW     + +   
Sbjct: 1603 KLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQG 1662

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-EFPPKIVD-YEREY 1297
              F+         L+I++ +  D   Y CV  ++    +  V +V    P+I + Y    
Sbjct: 1663 TTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLL 1722

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDSKSASLTIKKVENTDAG 1356
             I  G D+ L     A P P   W + S ++  + + +       + +L+I +    D G
Sbjct: 1723 SIINGEDLHLDCVSDAHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRG 1782

Query: 1357 IYKLRLENNCGHADVEMNVTILDKP 1381
             Y+ ++ N+ G + + ++V ++  P
Sbjct: 1783 TYRCQISNDHGSSSLSVSVIVIAYP 1807



 Score =  105 bits (251), Expect = 2e-20
 Identities = 220/1002 (21%), Positives = 372/1002 (37%), Gaps = 109/1002 (10%)

Query: 739  EPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDG-DTH--SITILKP 794
            + L ++ V  G  V L    VG PRP +TW K +   V +  TK    + H      ++ 
Sbjct: 934  DKLHTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTFTIRN 993

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
              ++D G Y   A N+ G  +    + V         P     R Q++TV    T  L  
Sbjct: 994  VHLQDRGQYLCSASNAHGTDKMMVTLVVLAHVPRMTSP-----RHQDVTVYIGNTALLQC 1048

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQN----FDGENIELVITNVDSEIDSGDYKCVASN 910
            +    P+P+I+W   +  +  S + TQ          +++  TN    +D+G YKC+ASN
Sbjct: 1049 QAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNY---LDTGVYKCIASN 1105

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEIS 968
            +AG      R+ I        +   ++Y   +G   ++ C  +   +   +W  +    S
Sbjct: 1106 AAGADMLSVRLQITALAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTS----S 1161

Query: 969  GMDHR--EIIQEGRXXXXXXXXX----XXXDVGVIKCIVKDQ----ETSTMLVVKETIPE 1018
            GM  R  + +                    D G+ +C+        + S  L VK     
Sbjct: 1162 GMQLRPSQFVNSNLFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKRSVNLQVKRNSGS 1221

Query: 1019 ---FIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRK- 1073
                       +V   D   L    + S T  ++W    +  K   + Y F++R  +   
Sbjct: 1222 ARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAK--KLVDSYYSFDRRMKVLSN 1279

Query: 1074 --LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITR-LQNQKVNKGNKATF 1126
              L I + +  DEGEY C  R    D+    +VTV+    +I  + L   KV  G +   
Sbjct: 1280 GTLTITSVTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSEHKVLYGGELKV 1339

Query: 1127 E-IELTKGDALVRW-FKDGSEIQ-FSNHIQLTIDGKKQ------KLKIYDCDLDDAGEYS 1177
            + I     +  V W   DG+ I    +  + TI  K+        L + +  + + G+Y+
Sbjct: 1340 DCIASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYT 1399

Query: 1178 C----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYK- 1231
            C    ++G  +    + V   +          I V     A L      E T  +TW   
Sbjct: 1400 CYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISP 1459

Query: 1232 -KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPP 1288
             KK ++  T K+ + +D    TL I K  + +   YTC+        +  + VEV+ FPP
Sbjct: 1460 DKKVIVPMTNKYQISND---GTLHIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPP 1516

Query: 1289 KIVDYEREYRIKRGS--DVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343
             I  +E    I++ +  D  +L D +A   P P   W+  + ++    +    I   ++ 
Sbjct: 1517 VINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNG 1576

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
            +L I  V  +D+        N  G   + + + + +      KP +    + SI +    
Sbjct: 1577 TLDIHAVRMSDSVELICIARNEFGETKLHVKLEVTEDII---KPQLRNSPTDSIQL---- 1629

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR---AYAVNEVD 1460
                G  T +   +E        W ++ N     TS+    T S +  R   A  + E  
Sbjct: 1630 --TIGKPTTLNCSIEGNPAPQITW-TLPN----GTSLYQGTTFSRFHHRSDGALLIKEPS 1682

Query: 1461 ISDAS------ETTEYYKVIKETKIQS--PTVEKPLKNITTEPN-EDIELTCIFGGVPQP 1511
             SDA         +  +     T + +  P +     ++ +  N ED+ L C+    P P
Sbjct: 1683 SSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742

Query: 1512 KVTW-YRDGKKLKTAKATYE----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVV 1565
            K+TW    G  L  A+++      N                Y+C   NDHG    S  V+
Sbjct: 1743 KLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVI 1802

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKE---YNI 1621
             I   P IT S        +VG    +       P  EV+W   +G +L+ D +   Y  
Sbjct: 1803 VIAYPPRIT-SGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQLKVDVQPRLYGN 1861

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
                   V++I       S  Y   A N  G+ S    + V+
Sbjct: 1862 KHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYVF 1903



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 166/792 (20%), Positives = 298/792 (37%), Gaps = 73/792 (9%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
            V+ G+D+ L C  V  P P + W       V   N  V    ++H       I NV    
Sbjct: 941  VNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQ-RFEVHPN-GTFTIRNVHLQD 998

Query: 705  EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPR 763
             G Y   A N  G   + + L +       P++  P  + + V  G + +L  Q  G P 
Sbjct: 999  RGQYLCSASNAHGTDKMMVTLVVLA---HVPRMTSPRHQDVTVYIGNTALLQCQAQGLPI 1055

Query: 764  PTITWCKNNKPVKALPTKSDGD----THSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            P I+W   ++ +    + +        +    +K     D GVY   A N+ G    S  
Sbjct: 1056 PNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSVR 1115

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSET 878
            + +         P +   R++  T+ +     +       P P++ W  ++ + + PS+ 
Sbjct: 1116 LQITA-----LAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQF 1170

Query: 879  ITQN-FDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKVTFVKHLQ 935
            +  N F   N  L I N   + DSG Y+CVA +S G  K S   +V  +      +    
Sbjct: 1171 VNSNLFVFPNGTLFIRNPTVK-DSGIYECVAVSSVGMAKRSVNLQVKRNSGSARILSTSA 1229

Query: 936  KSYETEEGKTVILECQTSHTVSTK--WYHNKKEI----SGMDHR-EIIQEGRXXXXXXXX 988
             S +   G  + L C  S + + +  W    K++       D R +++  G         
Sbjct: 1230 HSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYYSFDRRMKVLSNG---TLTITS 1286

Query: 989  XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI---LEVEINSE-- 1043
                D G   C  ++      +++K T+     K+    + E  V     L+V+  +   
Sbjct: 1287 VTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSEHKVLYGGELKVDCIASGL 1346

Query: 1044 -TADVVWE-RDGEIIKP--KKNKYDFEKRGHIR----KLYIRNTSVHDEGEYSCILRD-- 1093
               +V W   DG +I      +K     + ++      LY+    + +EG+Y+C  ++  
Sbjct: 1347 PNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQM 1406

Query: 1094 --ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGD--ALVRWFKDGSE--I 1146
              +     + V+   P I     +  KV  G  A       KG+   ++ W     +  +
Sbjct: 1407 GKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCS-AKGEPTPVITWISPDKKVIV 1465

Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG-NSKCTAILTVEEPSINFTLR 1201
              +N  Q++ DG    L I+     ++G Y+C     VG + K   +  +  P +     
Sbjct: 1466 PMTNKYQISNDG---TLHIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFE 1522

Query: 1202 LPEFILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKF-TLISDVKKRTLIIRK 1257
             P  I   A  D  +  +     +    + W    +V+     + + I+  +  TL I  
Sbjct: 1523 HPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDIHA 1582

Query: 1258 CTEDDQCEYTCVLLDAKSTTKL--KVEVVE--FPPKIVDYERE-YRIKRGSDVTLLVDYQ 1312
                D  E  C+  +    TKL  K+EV E    P++ +   +  ++  G   TL    +
Sbjct: 1583 VRMSDSVELICIARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIE 1642

Query: 1313 AFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
              P P   W + N   + +             +L IK+  ++DAG+Y+    N+ G   V
Sbjct: 1643 GNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGF--V 1700

Query: 1372 EMNVTILDKPSP 1383
            E NVT++    P
Sbjct: 1701 ERNVTLVSNRKP 1712



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 86/408 (21%), Positives = 141/408 (34%), Gaps = 53/408 (12%)

Query: 527  VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
            V F+C+  G P P+I W     ++ P+  +          TL I  V   D+    C+A+
Sbjct: 1537 VLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDIHAVRMSDSVELICIAR 1596

Query: 587  NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646
            N  G     T+L V+  +++                    DI++  P   +    +  + 
Sbjct: 1597 NEFG----ETKLHVKLEVTE--------------------DIIK--PQLRNSPTDSIQLT 1630

Query: 647  EGSDILLECRLVAIPEPDIAW-LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
             G    L C +   P P I W L  G  +      S       H     L I        
Sbjct: 1631 IGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFS----RFHHRSDGALLIKEPSSSDA 1686

Query: 706  GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRP 764
            G Y  V  N  G     + L         P++     S++ +  GE + L      +P P
Sbjct: 1687 GLYRCVGRNSGGFVERNVTLV----SNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742

Query: 765  TITWCKNNKPVKALPTKSDGDTHSI----TI-LKPKKVKDEGVYTLKAENSEGIAETSAV 819
             +TW   +  V  L        HS+    T+ +    V D G Y  +  N  G +  S  
Sbjct: 1743 KLTWTLPSGVV--LSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVS 1800

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSET 878
            + V       A PP   +    +T    G  + L  R   +P   + W   + +    + 
Sbjct: 1801 VIVI------AYPPRITSGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQLKVDV 1854

Query: 879  ITQNFDGENIE---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              + +  +++    ++  +  S  DSG YKC A N  G  S    V +
Sbjct: 1855 QPRLYGNKHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYV 1902



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 89/438 (20%), Positives = 155/438 (35%), Gaps = 24/438 (5%)

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY---RIKRGSDVTLL 1308
            TL + +    ++ +YTC   +     ++KV +       V     Y   ++  G    L 
Sbjct: 1384 TLYLNEVGMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILN 1443

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
               +  P P   WI   K +      K  I S   +L I K +  ++G Y     +  G 
Sbjct: 1444 CSAKGEPTPVITWISPDKKVIVPMTNKYQI-SNDGTLHIHKTQKINSGNYTCMARSVVGI 1502

Query: 1369 ADVEMNVTILDKPSPPG---KPNILEIDSSSINICWDEPENTGNS--TIIYYVVEYQEID 1423
                + V +L  P        P I+   +        + +  GN    II+       + 
Sbjct: 1503 DRKVVLVEVLVFPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLP 1562

Query: 1424 TTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQS 1481
               + S   + +  T  I  ++ + S      A NE       ET  + K+ + E  I+ 
Sbjct: 1563 APYYGSRITVHRNGTLDIHAVRMSDSVELICIARNEF-----GETKLHVKLEVTEDIIKP 1617

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKL--KTAKATYENRXXXXXX 1538
                 P  +I     +   L C   G P P++TW   +G  L   T  + + +R      
Sbjct: 1618 QLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALL 1677

Query: 1539 XX--XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                       Y+C+  N  G VE +  +   +KP IT     +      G++  +  V 
Sbjct: 1678 IKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLLSIIN-GEDLHLDCVS 1736

Query: 1597 EGIPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            +  PPP++ W   +G  L   +     +      + I          Y  + SN  G+SS
Sbjct: 1737 DAHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSS 1796

Query: 1656 VEVTLKVYDKPSK-PEGP 1672
            + V++ V   P +   GP
Sbjct: 1797 LSVSVIVIAYPPRITSGP 1814



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 9/118 (7%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            + +E +YT Y + ++ +  D++ V  K  ++   +       ++  +   G T    C  
Sbjct: 1392 MKEEGDYTCYAKNQMGK--DEMKVHIKVLADAPVIRNNAYSVIKVTY---GETAILNCSA 1446

Query: 534  EGYPRPQITWFR-QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            +G P P ITW      +I P  +    Y   N  TL I +    ++G +TC+A++  G
Sbjct: 1447 KGEPTPVITWISPDKKVIVPMTN---KYQISNDGTLHIHKTQKINSGNYTCMARSVVG 1501


>UniRef50_Q172S1 Cluster: Stretchin-mlck; n=1; Aedes aegypti|Rep:
           Stretchin-mlck - Aedes aegypti (Yellowfever mosquito)
          Length = 712

 Score =  110 bits (265), Expect = 4e-22
 Identities = 111/434 (25%), Positives = 179/434 (41%), Gaps = 52/434 (11%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P+ +  L+ +  P GSTV+  C + G P   + WF+    I+ S     +   + + +L 
Sbjct: 284 PLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAK-HTFKVSEGLLSLE 341

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
           I  V   D G ++C+ KN  G  S++T + V                             
Sbjct: 342 IVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFES----------------------- 378

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           + IPPTF    K  Y     +I+LECR+   P P+IAW+  GE I+P +       +D  
Sbjct: 379 KPIPPTFISI-KETYSLHSDEIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGT 437

Query: 690 MYCSVLKITNVKKFQEGTYTVVA------------VNREGEASLPIVLKIKTGEKEP--P 735
             C ++ IT   +   GTYT  A            V   G+  + +        + P  P
Sbjct: 438 --CKLI-ITKPGEEDSGTYTCEAESGGCSDAISHNVQFVGKEKIMMERTHSYYHRNPNLP 494

Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITI 791
              + L    +  G ++ L  +V GN    + W K+   VK  P K    SDG       
Sbjct: 495 HFYQSLADYSIPSGGNICLVVEVQGNCE--VQWFKDKYEVKGRPPKFRFYSDGTGVFALC 552

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQ-EITVKEKGT 849
           +    +   G YT +A N+ G AE+S+ + V  P   + A+PP+F+ R Q EI +++   
Sbjct: 553 ITAATMDASGKYTCRATNAFGKAESSSNVDVINPNAIKGAKPPIFMARPQPEIKIRQGQE 612

Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
           I +  ++  +P P I W +  + I+ +    +    + I   I       D G Y  VA 
Sbjct: 613 ISMAFKIIGDPKPKIQWMKGTKDITNAARTVKEVHNDFIRFSIKEA-LTTDEGAYFIVAR 671

Query: 910 NSAGKSSHGARVTI 923
           N  G      +VT+
Sbjct: 672 NRYGIDRCFTKVTV 685



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 86/358 (24%), Positives = 142/358 (39%), Gaps = 26/358 (7%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           D+  Y+  ++ K  E      V    + E + + P F+  ++  ++     +  EC+V G
Sbjct: 349 DQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFIS-IKETYSLHSDEIVLECRVRG 407

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
            PRP I W +    I P   ++ Y   D    L+I +   ED+GT+TC A+  +G  S  
Sbjct: 408 SPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAE--SGGCSDA 465

Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
               V+      G E  +             ++     P F +      +  G +I   C
Sbjct: 466 ISHNVQFV----GKE-KIMMERTHSYYHRNPNL-----PHFYQSLADYSIPSGGNI---C 512

Query: 656 RLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
            +V +    ++ W FK +  V          SD       L IT       G YT  A N
Sbjct: 513 LVVEVQGNCEVQW-FKDKYEVKGRPPKFRFYSD-GTGVFALCITAATMDASGKYTCRATN 570

Query: 715 REGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769
             G+A     + +       G K P  +  P   + +RQG+ + ++ +++G+P+P I W 
Sbjct: 571 AFGKAESSSNVDVINPNAIKGAKPPIFMARPQPEIKIRQGQEISMAFKIIGDPKPKIQWM 630

Query: 770 KNNKPV-KALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
           K  K +  A  T  +     I   +K     DEG Y + A N  GI      +TV+ P
Sbjct: 631 KGTKDITNAARTVKEVHNDFIRFSIKEALTTDEGAYFIVARNRYGIDRCFTKVTVKHP 688



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 69/257 (26%), Positives = 109/257 (42%), Gaps = 26/257 (10%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           PP +I  LKS    +G +V L+  + G P  T+ W K+  P++     +   +  +  L+
Sbjct: 283 PPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLSLE 341

Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
              V   D+G Y+   +N  G   TS  + V E  E    PP FI+  +E        I 
Sbjct: 342 IVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFIS-IKETYSLHSDEIV 400

Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQ--NFDGENIELVITNVDSEIDSGDYKCVAS 909
           L  RV  +P P+I W ++ E I P +   Q  + DG   +L+IT    E DSG Y C A 
Sbjct: 401 LECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADG-TCKLIITKPGEE-DSGTYTCEAE 458

Query: 910 NS--AGKSSHGARVTIDVEKVTF------------VKHLQKS---YETEEGKTVILECQT 952
           +   +   SH  +  +  EK+              + H  +S   Y    G  + L  + 
Sbjct: 459 SGGCSDAISHNVQF-VGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEV 517

Query: 953 SHTVSTKWYHNKKEISG 969
                 +W+ +K E+ G
Sbjct: 518 QGNCEVQWFKDKYEVKG 534



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 73/309 (23%), Positives = 125/309 (40%), Gaps = 26/309 (8%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP      K++   +GS + L C +   P   + W   G  I      +  +   +    
Sbjct: 283 PPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLS-- 339

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEP-PQVIEPLKSMIVRQGE 750
             L+I NV    +G Y+ +  N+ GE S    +K+ ++ E +P P     +K       +
Sbjct: 340 --LEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSD 397

Query: 751 SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGD-THSITILKPKKVKDEGVYTLK 806
            ++L  +V G+PRP I W K+ +   P          D T  + I KP + +D G YT +
Sbjct: 398 EIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGE-EDSGTYTCE 456

Query: 807 AEN---SEGIAETSAVITVEEPTEE--------NAEPPLFINRFQEITVKEKGTIKLVAR 855
           AE+   S+ I+     +  E+   E        N   P F     + ++   G I LV  
Sbjct: 457 AESGGCSDAISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVE 516

Query: 856 VTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
           V  N    + W+++  E+           DG  +  +     +   SG Y C A+N+ GK
Sbjct: 517 VQGN--CEVQWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNAFGK 574

Query: 915 SSHGARVTI 923
           +   + V +
Sbjct: 575 AESSSNVDV 583



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 93/395 (23%), Positives = 160/395 (40%), Gaps = 47/395 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
            P  I  L+     +     L   I+     V W +DG  I+ K  K+ F+    +  L I
Sbjct: 284  PLIISHLKSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIE-KSAKHTFKVSEGLLSLEI 342

Query: 1077 RNTSVHDEGEYSCILRDE----SCTAEVTVVE------LPPEIITRLQNQKVNKGNKATF 1126
             N    D+GEYSCI++++    S +  V V E      +PP  I+  +   ++  ++   
Sbjct: 343  VNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHS-DEIVL 401

Query: 1127 EIELTKGDAL-VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
            E  +       + W KDG  I     + Q        KL I     +D+G Y+CE  +  
Sbjct: 402  ECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGG 461

Query: 1185 CTAILT-----------VEEPSINFTLR---LPEFIL------VPANTDAYLTVEIPDET 1224
            C+  ++           + E + ++  R   LP F        +P+  +  L VE+    
Sbjct: 462  CSDAISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEVQGNC 521

Query: 1225 LDVTWYKKKSVIEDTE-KFTLISD-VKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLK 1280
             +V W+K K  ++    KF   SD      L I   T D   +YTC   +A  K+ +   
Sbjct: 522  -EVQWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNAFGKAESSSN 580

Query: 1281 VEVVE-------FPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332
            V+V+         PP  +   + E +I++G ++++       P+P  +W+  +K I    
Sbjct: 581  VDVINPNAIKGAKPPIFMARPQPEIKIRQGQEISMAFKIIGDPKPKIQWMKGTKDITNAA 640

Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             T   + +     +IK+   TD G Y +   N  G
Sbjct: 641  RTVKEVHNDFIRFSIKEALTTDEGAYFIVARNRYG 675



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 60/261 (22%), Positives = 107/261 (40%), Gaps = 17/261 (6%)

Query: 1420 QEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
            +E D + W SV ++ T+ + S +  K   +   +  +          E TE  + ++  +
Sbjct: 217  EEFDPSVWKSVDDLETQLKNSEEETKKAKAKEAKEASKESSRRESTHEMTERERDLEWQR 276

Query: 1479 ----IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY---E 1530
                ++ P +   LK+        ++LTC   G P   V W++DG  + K+AK T+   E
Sbjct: 277  QRQLMRPPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSE 335

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI----QQKPVITISNEDIKQKHKV 1586
                             Y CI  N +GE  TS  V +    + KP I  +   IK+ + +
Sbjct: 336  GLLSLEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKP-IPPTFISIKETYSL 394

Query: 1587 -GDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
              DE ++   + G P P + W K+G   +  DK       + T  + I +     S  YT
Sbjct: 395  HSDEIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYT 454

Query: 1645 IEASNTAGTSSVEVTLKVYDK 1665
             EA +   + ++   ++   K
Sbjct: 455  CEAESGGCSDAISHNVQFVGK 475



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 68/288 (23%), Positives = 109/288 (37%), Gaps = 38/288 (13%)

Query: 931  VKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXX 988
            + HL KS    +G TV L C  S   ++ +W+ +   I     H   + EG         
Sbjct: 287  ISHL-KSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEG-LLSLEIVN 344

Query: 989  XXXXDVGVIKCIVKDQ--ETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAILEVE 1039
                D G   CI+K++  ETST   VK       + IP     +++      D  +LE  
Sbjct: 345  VDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSDEIVLECR 404

Query: 1040 IN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT- 1097
            +  S   ++ W +DGE I P      ++      KL I      D G Y+C      C+ 
Sbjct: 405  VRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGGCSD 464

Query: 1098 ----------AEVTVVELP----------PEIITRLQNQKVNKGNKATFEIELTKGDALV 1137
                       E  ++E            P     L +  +  G      +E+ +G+  V
Sbjct: 465  AISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEV-QGNCEV 523

Query: 1138 RWFKDGSEIQ-FSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGNS 1183
            +WFKD  E++      +   DG     L I    +D +G+Y+C   N+
Sbjct: 524  QWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNA 571



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 10/173 (5%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            PP II+ L+++   KG+       ++     VRWFKDG+ I+ S      +      L+I
Sbjct: 283  PPLIISHLKSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEGLLSLEI 342

Query: 1166 YDCDLDDAGEYSCEVGNSKC-TAILTVEEPSINFTLR-LPEFILVPANTDAYLTVEIPDE 1223
             + D  D GEYSC + N    T+  T  +   +F  + +P   +    T +  + EI  E
Sbjct: 343  VNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSDEIVLE 402

Query: 1224 TL-------DVTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTC 1268
                     ++ W K    I   +K+           LII K  E+D   YTC
Sbjct: 403  CRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTC 455



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 12/182 (6%)

Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
            P  +   LT  I    + V W+K  + IE + K T        +L I      DQ EY+C
Sbjct: 296  PKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEGLLSLEIVNVDYSDQGEYSC 355

Query: 1269 VL--LDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320
            ++   + +++T   V+V E       PP  +  +  Y +    ++ L    +  P+PN  
Sbjct: 356  IIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSL-HSDEIVLECRVRGSPRPNIA 414

Query: 1321 WIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN-NCGHADVEMNVTIL 1378
            WI + + II   K+ +      +  L I K    D+G Y    E+  C  A +  NV  +
Sbjct: 415  WIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGGCSDA-ISHNVQFV 473

Query: 1379 DK 1380
             K
Sbjct: 474  GK 475



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
            +P + IS+   +   K G    +T  I G P   V W+K+GN +E   ++     E    
Sbjct: 282  RPPLIISHLKSRAAPK-GSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLS 339

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPEGPVIM 1675
            + I  +  S   +Y+    N  G +S   T+KVY+   SKP  P  +
Sbjct: 340  LEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFI 386


>UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin;
            n=1; Bos taurus|Rep: PREDICTED: similar to hemicentin -
            Bos taurus
          Length = 2756

 Score =  110 bits (264), Expect = 5e-22
 Identities = 134/575 (23%), Positives = 229/575 (39%), Gaps = 65/575 (11%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIV--PDENISVAIESDMH 689
            PP+ S         +G + +LEC    +P P + W ++G+ E++  P+++IS        
Sbjct: 1147 PPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIW-YRGDLEMILAPEDSIS-------- 1197

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
                +L+I  V++   G YT  AVN  G+AS  I L++       PQ++E  + + V  G
Sbjct: 1198 ---GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVG----HAPQLLELPQDVTVELG 1250

Query: 750  ESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKA 807
             S +L+ +  G+P PTITW + +++P+   P    G   S +   +    +D+ +Y  +A
Sbjct: 1251 RSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEA 1310

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV-TRNPVPSITW 866
            EN  G  +  A + V         PP   +    + V E+  + L   V    P P   W
Sbjct: 1311 ENVFGKVQAEAYLLV-----TGHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRW 1365

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             +    + P    +   DG ++ L    ++   D+G Y CV SN+AG  SH   V + V+
Sbjct: 1366 LKAGMPLPPGSRHSIRADG-SLHLDQALLE---DAGRYSCVVSNTAG--SHHRDVQLVVQ 1419

Query: 927  KVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-HREIIQEGRXXX 983
                ++     + T EG    L C  S   T +  W      ++  D H  + ++G    
Sbjct: 1420 VPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG---T 1476

Query: 984  XXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFI-------RKLQDFEVKEKDV 1033
                     D G   C   +     +  M +   T P  +        K      K  D 
Sbjct: 1477 LVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAKAGDE 1536

Query: 1034 AILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
              L+ E       +V W +D   + P  +++     G    L++    V D G Y C   
Sbjct: 1537 VTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPG---SLHLAQAQVSDSGLYECTAS 1593

Query: 1093 DESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQF 1148
            + + +A    +  V++PP++    +  KV  G       +     +  V W KDG     
Sbjct: 1594 NPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDG----- 1648

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
               + L  +G +  +         AG Y CE  +S
Sbjct: 1649 ---VALRGEGPEGSVHFAAIQTSHAGTYRCEASSS 1680



 Score =  100 bits (239), Expect = 5e-19
 Identities = 153/732 (20%), Positives = 275/732 (37%), Gaps = 76/732 (10%)

Query: 696  KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            +I    K +EGTY   AV+R G       + + TG   PPQ++ P+ ++ V  GE+ ILS
Sbjct: 932  EIPRASKAEEGTYECTAVSRAGTGRAKTQIVV-TGP--PPQLV-PVPNVTVSPGETAILS 987

Query: 756  AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
              V+      +TW ++ + + A   +          ++     D G Y   A NS G+  
Sbjct: 988  CLVLSEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTR 1047

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
             S  + V E  + +        R Q  +  +   +++    +  P P I+W R    +  
Sbjct: 1048 ASVWLLVREAPQVSIH-----TRSQRFS--QGMEVRVRCSASGYPAPHISWSREGRALQE 1100

Query: 876  SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
               +  +  G    L+I  V  E D+G Y C A+N  G+      VT+       V  + 
Sbjct: 1101 DSRVRVDAQG---TLIIQGVAPE-DAGSYSCQAANEIGRDEE--TVTLYYTDPPSVSAVN 1154

Query: 936  KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993
                  +G+  +LEC+ +     +  WY    E+       I                 D
Sbjct: 1155 GVVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI-----SGMLRIPVVRERD 1209

Query: 994  VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVW 1049
             GV  C   ++       ++  +   P+ +   QD  V+    A+L           + W
Sbjct: 1210 AGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW 1269

Query: 1050 ER--DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVV 1103
             R  D  +     ++  +   G    L+  +    D+  Y C    +       A + V 
Sbjct: 1270 HRGDDQPLGLRPGSRTGWPDSG---VLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVT 1326

Query: 1104 -ELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLTIDGKK 1160
              +PP+I +     +V +    +    +  G      RW K G  +   +   +  DG  
Sbjct: 1327 GHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRADG-- 1384

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN---TDAYLT 1217
              L +    L+DAG YSC V N+  +         +   +++P  I   A    T+  + 
Sbjct: 1385 -SLHLDQALLEDAGRYSCVVSNTAGS-----HHRDVQLVVQVPPRIQPTATHHITNEGVP 1438

Query: 1218 VEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              +P       T  +TW K+ + +   +    +S  K  TL+I + +  D   Y C   +
Sbjct: 1439 ASLPCVASGVPTPTITWTKETNALASRDPHYNVS--KDGTLVIPRPSVQDAGAYVCTATN 1496

Query: 1273 AKSTTKLKVEV-VEFPPKIV-----DYEREYRI--KRGSDVTLLVDYQAFPQPNDEWIVN 1324
            A   +  ++ + V   P+I+     + ++  R+  K G +VTL  + Q  P P   W   
Sbjct: 1497 AVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW--- 1553

Query: 1325 SKIIKKCKHTKPSIDS----KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
                K  +H  P  D        SL + + + +D+G+Y+    N  G A     + +   
Sbjct: 1554 ---TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVP 1610

Query: 1381 PSPPGKPNILEI 1392
            P     P +L++
Sbjct: 1611 PQVQPGPRVLKV 1622



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 110/472 (23%), Positives = 188/472 (39%), Gaps = 46/472 (9%)

Query: 632  IPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            +PPT     + P+      G  + LEC     P P ++W  +G  +V      +      
Sbjct: 2209 VPPTIEGTGEGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGG-- 2266

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
                 VL + ++ +   G Y+ VA +  GEA L   ++++   +    V E L  +    
Sbjct: 2267 ----GVLSLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQL--LVAEGLGQVTTLV 2320

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTL 805
            G+S+ L     G+P PTI W +N  P + LP     S+G T  I  ++   +   G++  
Sbjct: 2321 GQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEGTTLHIDHVE---LGHAGLFAC 2377

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            +A N  G A     ++V E       P + I   + IT      + L    T  P PS+ 
Sbjct: 2378 QATNEAGTAAAEVELSVHEL------PSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLR 2431

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W+++   ++ S        G +++  I  VD + D G Y CVA+N AG+S     + + V
Sbjct: 2432 WWKDGVALAAS--------GGSLQ--IEKVDLK-DEGTYTCVATNLAGESRKEVILRVLV 2480

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXX 983
                    + K+    E  +V LEC  S        W+  ++ IS  D   +  +GR   
Sbjct: 2481 PPNIEPGLVNKA--VLENASVTLECLASGVPPPDISWFKGRQPISAWDRAMVSTDGRVLL 2538

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLV--VKETIPEFIR---KLQDFEVKEKDVAILEV 1038
                     D G  +C+  +   ST L   ++  +P  I     L    +    V +   
Sbjct: 2539 IEQAQLS--DAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
               + +  ++W +DG  +         +     R L + +  V D G YSC+
Sbjct: 2597 AAGAPSPMLMWLKDGNPVSTAGTA-GLQVFPGGRVLMLASARVSDSGSYSCV 2647



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 158/780 (20%), Positives = 299/780 (38%), Gaps = 77/780 (9%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            ++ G PP     P    V  G   +L C +++    ++ W+ +   ++      V   +D
Sbjct: 962  VVTGPPPQLVPVPNVT-VSPGETAILSCLVLSEAPYNLTWV-RDWRVLSASTGRVTQLAD 1019

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            +      L++ N      G Y  +A N  G     + L ++    E PQV    +S    
Sbjct: 1020 LS-----LEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVR----EAPQVSIHTRSQRFS 1070

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            QG  V +     G P P I+W +  + ++   ++   D     I++    +D G Y+ +A
Sbjct: 1071 QGMEVRVRCSASGYPAPHISWSREGRALQE-DSRVRVDAQGTLIIQGVAPEDAGSYSCQA 1129

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             N  G  E +  +   +P   +A   + +    E  V E          T  P P + WY
Sbjct: 1130 ANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLE-------CEATGVPPPRVIWY 1182

Query: 868  RNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            R +   I++P ++I+         ++   V  E D+G Y C A N  G +S  A + ++V
Sbjct: 1183 RGDLEMILAPEDSISG--------MLRIPVVRERDAGVYTCRAVNELGDAS--AEIRLEV 1232

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXX 983
                 +  L +    E G++ +L C+ T H + T  W+    +  G+             
Sbjct: 1233 GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292

Query: 984  XXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE- 1037
                     D  +  C  ++     Q  + +LV     P+         V E+    L  
Sbjct: 1293 LFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVSLPC 1352

Query: 1038 -VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             V       +  W + G  + P  +++     G    L++    + D G YSC++ + + 
Sbjct: 1353 IVLAGRPRPERRWLKAGMPLPPG-SRHSIRADG---SLHLDQALLEDAGRYSCVVSNTAG 1408

Query: 1097 TAE---VTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSN-H 1151
            +       VV++PP I     +   N+G  A+   +        + W K+ + +   + H
Sbjct: 1409 SHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPH 1468

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
              ++ DG    L I    + DAG Y C   N+   +   +   S+N   R+       A+
Sbjct: 1469 YNVSKDGT---LVIPRPSVQDAGAYVCTATNAVGFSSQEMRL-SVNTKPRILVNGSHEAD 1524

Query: 1212 TDAYLTVEIPDE-TLD----------VTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCT 1259
                +T +  DE TLD          VTW K  + ++  T++  L+      +L + +  
Sbjct: 1525 KPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPP---GSLHLAQAQ 1581

Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318
              D   Y C   + A S T+  +  V+ PP++    R  ++  G  V L    +  P+P 
Sbjct: 1582 VSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPR 1641

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
              W  +   ++         +    S+    ++ + AG Y+    ++ G    E+++ +L
Sbjct: 1642 VTWSKDGVALRG--------EGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVL 1693



 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 160/788 (20%), Positives = 276/788 (35%), Gaps = 54/788 (6%)

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSH 954
            S+ + G Y+C A + AG      ++ +       V     +     G+T IL C   +  
Sbjct: 937  SKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVP--VPNVTVSPGETAILSCLVLSEA 994

Query: 955  TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTML 1010
              +  W  + + +S    R  + +              D G  +C+  +       S  L
Sbjct: 995  PYNLTWVRDWRVLSASTGR--VTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVWL 1052

Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH 1070
            +V+E     I        +  +V +           + W R+G  ++ + ++   + +G 
Sbjct: 1053 LVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQ-EDSRVRVDAQG- 1110

Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL---PPEIITRLQNQKVNKGNKATFE 1127
               L I+  +  D G YSC   +E    E TV      PP +          KG +A  E
Sbjct: 1111 --TLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLE 1168

Query: 1128 IELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--K 1184
             E T      V W++   E+     I    D     L+I      DAG Y+C   N    
Sbjct: 1169 CEATGVPPPRVIWYRGDLEM-----ILAPEDSISGMLRIPVVRERDAGVYTCRAVNELGD 1223

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFT 1243
             +A + +E       L LP+ + V     A L        L  +TW++           +
Sbjct: 1224 ASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGS 1283

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRIK 1300
                     L       +DQ  Y C   +     + +  ++     PP+I       R+ 
Sbjct: 1284 RTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVL 1343

Query: 1301 RGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
                V+L  +     P+P   W+     +     ++ SI +   SL + +    DAG Y 
Sbjct: 1344 ERQPVSLPCIVLAGRPRPERRWLKAGMPLPP--GSRHSIRA-DGSLHLDQALLEDAGRYS 1400

Query: 1360 LRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
              + N  G  H DV++ V +  +  P    +I      +   C      T   T   +  
Sbjct: 1401 CVVSNTAGSHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTIT---WTK 1457

Query: 1418 EYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            E   + + +     N++K  T  I       +  +   A N V  S            + 
Sbjct: 1458 ETNALASRD--PHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRI 1515

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXX 1534
                S   +KPL+ +T +  +++ L C   G P P VTW +D + +   T +        
Sbjct: 1516 LVNGSHEADKPLR-VTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGS 1574

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y+C A N  G      ++ +Q  P +      +K    VG+   +  
Sbjct: 1575 LHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVL--VGEAVDLNC 1632

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            V EG P P V W K+G  L  +             +    ++ SH+  Y  EAS++AG  
Sbjct: 1633 VAEGSPEPRVTWSKDGVALRGEGP--------EGSVHFAAIQTSHAGTYRCEASSSAGVD 1684

Query: 1655 SVEVTLKV 1662
            + E+ L+V
Sbjct: 1685 AWELDLRV 1692



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 137/702 (19%), Positives = 259/702 (36%), Gaps = 54/702 (7%)

Query: 1008 TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFE 1066
            T +VV    P+ +  + +  V   + AIL   + SE   ++ W RD  ++     +    
Sbjct: 959  TQIVVTGPPPQLV-PVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVT-- 1015

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNK 1123
            +   +  L +RNT+  D G Y C+  + +     +V   V   P++    ++Q+ ++G +
Sbjct: 1016 QLADL-SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQRFSQGME 1074

Query: 1124 ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178
                   +   A  + W ++G  +Q  + +++   G    L I     +DAG YSC    
Sbjct: 1075 VRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQGT---LIIQGVAPEDAGSYSCQAAN 1131

Query: 1179 EVGNSKCTAILT-VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVI 1236
            E+G  + T  L   + PS++    +   +L     +A L  E        V WY+     
Sbjct: 1132 EIGRDEETVTLYYTDPPSVS---AVNGVVLAAKGEEAVLECEATGVPPPRVIWYRG---- 1184

Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER 1295
             D E      D     L I    E D   YTC  ++       ++ + V   P++++  +
Sbjct: 1185 -DLEMILAPEDSISGMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQ 1243

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +  ++ G    L       P P   W          +    +    S  L  + V   D 
Sbjct: 1244 DVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQ 1303

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415
             +Y    EN  G    E  + +     P       +I SS+  +   E +      I   
Sbjct: 1304 ALYVCEAENVFGKVQAEAYLLVTGHVPP-------QIASSAPTVRVLERQPVSLPCI--- 1353

Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA--SETT-EYYK 1472
            V+  +      W+    +     S  +++ + S       + +        S T   +++
Sbjct: 1354 VLAGRPRPERRWLKA-GMPLPPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHR 1412

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--E 1530
             ++      P ++    +  T       L C+  GVP P +TW ++   L +    Y   
Sbjct: 1413 DVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVS 1472

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI-----SNEDIKQKHK 1585
                             Y C A N  G       + +  KP I +     +++ ++   K
Sbjct: 1473 KDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAK 1532

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
             GDE  +    +G PPP V W K+   +    D+ + +        + + + + S S  Y
Sbjct: 1533 AGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLL----PPGSLHLAQAQVSDSGLY 1588

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
               ASN AG+++    L+V   P    GP +++ +  E+V +
Sbjct: 1589 ECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDL 1630



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 108/511 (21%), Positives = 200/511 (39%), Gaps = 36/511 (7%)

Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DT 1239
            G +K   ++T   P +   + +P   + P  T     + + +   ++TW +   V+   T
Sbjct: 955  GRAKTQIVVTGPPPQL---VPVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSAST 1011

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR 1298
             + T ++D+   +L +R  T  D   Y C+  ++   T+  V + V   P++  + R  R
Sbjct: 1012 GRVTQLADL---SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQR 1068

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
              +G +V +      +P P+  W    + +++    +  +D++  +L I+ V   DAG Y
Sbjct: 1069 FSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVR--VDAQG-TLIIQGVAPEDAGSY 1125

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418
              +  N  G  +  + +   D PS      ++        +   E        +I+Y  +
Sbjct: 1126 SCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYRGD 1185

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
             + I   E  S+  + +    I  ++   +  +   AVNE  + DAS      ++  E  
Sbjct: 1186 LEMILAPE-DSISGMLR----IPVVRERDAGVYTCRAVNE--LGDASA-----EIRLEVG 1233

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKL---KTAKATYENRXX 1534
                 +E P +++T E      L C   G P P +TW+R D + L     ++  + +   
Sbjct: 1234 HAPQLLELP-QDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEV--ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                         Y C A N  G+V  E   +V     P I  S   ++   +     L 
Sbjct: 1293 LFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVS-LP 1351

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
              V+ G P PE  W K G  L     ++I        + + +     + +Y+   SNTAG
Sbjct: 1352 CIVLAGRPRPERRWLKAGMPLPPGSRHSI---RADGSLHLDQALLEDAGRYSCVVSNTAG 1408

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683
            +   +V L V   P     P     I+ E V
Sbjct: 1409 SHHRDVQLVVQVPPRIQ--PTATHHITNEGV 1437



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 114/550 (20%), Positives = 204/550 (37%), Gaps = 45/550 (8%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTV 1191
            + WFKDG  +  S  +  T  G+  +L++      DAG YSC+  N+     K T +   
Sbjct: 2151 ITWFKDGDPLVPSTEVVYTRGGR--QLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVY 2208

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVE-----IPDETLDVTWYKKKSVIEDTEKFTLIS 1246
              P+I  T   P   +V A     LT+E      P  T  V+WY +   + D     L  
Sbjct: 2209 VPPTIEGTGEGPR--VVKAVAGRPLTLECVARGYPPPT--VSWYHEGLPVVDRNGTWL-- 2262

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR--GS 1303
                  L +    E     Y+CV         L   V V+  P+++  E   ++    G 
Sbjct: 2263 GAGGGVLSLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQ 2322

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
             + L       P P  +W+ N    ++       + S+  +L I  VE   AG++  +  
Sbjct: 2323 SLYLPCYASGSPVPTIQWLQNGHPAEELPGV--HVTSEGTTLHIDHVELGHAGLFACQAT 2380

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423
            N  G A  E+ +++ + PS      ++ +   +I   + +P      T+           
Sbjct: 2381 NEAGTAAAEVELSVHELPS------VVIVGGENITAPFLQP-----VTLRCAGTGVPTPS 2429

Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
               W     +  +  S+Q  K +       Y     +++  S      +V+    I+   
Sbjct: 2430 LRWWKDGVALAASGGSLQIEKVDLKDE-GTYTCVATNLAGESRKEVILRVLVPPNIEPGL 2488

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXX 1540
            V K +       N  + L C+  GVP P ++W++  + +     A  + + R        
Sbjct: 2489 VNKAVLE-----NASVTLECLASGVPPPDISWFKGRQPISAWDRAMVSTDGR-VLLIEQA 2542

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y+C+A N  G  E    + +   P IT+    +     +     +T    G P
Sbjct: 2543 QLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLP-PSLPGPVLLHSPVRLTCDAAGAP 2601

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
             P ++W K+GN +       +       V+ +   + S S  Y+  A +  G    +V L
Sbjct: 2602 SPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGEDRRDVVL 2661

Query: 1661 KVYDKPSKPE 1670
            +V+ +   PE
Sbjct: 2662 RVHSESRAPE 2671



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 59/221 (26%), Positives = 92/221 (41%), Gaps = 13/221 (5%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
            L+I  V    EGTYT VA N  GE+   ++L++      PP +   L +  V +  SV L
Sbjct: 2446 LQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLV----PPNIEPGLVNKAVLENASVTL 2501

Query: 755  SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
                 G P P I+W K  +P+ A           + +++  ++ D G Y   A N  G  
Sbjct: 2502 ECLASGVPPPDISWFKGRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGST 2561

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
            E    + V  P      P L         V     ++L       P P + W ++   +S
Sbjct: 2562 ELQYSLRVNVPPRITLPPSL------PGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVS 2615

Query: 875  PSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             + T   Q F G  + ++ +   S  DSG Y CVA ++ G+
Sbjct: 2616 TAGTAGLQVFPGGRVLMLASARVS--DSGSYSCVAVSAVGE 2654



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 68/338 (20%), Positives = 137/338 (40%), Gaps = 24/338 (7%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNI-LEIDSSS 1396
            +S ++S  I +    + G Y+    +  G    +  + +   P      PN+ +    ++
Sbjct: 925  ESGNSSWEIPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVPNVTVSPGETA 984

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            I  C    E   N T   +V +++ +  +    V  +      ++N   +   R++  A 
Sbjct: 985  ILSCLVLSEAPYNLT---WVRDWRVLSASTG-RVTQLADLSLEVRNTTPSDGGRYQCMAS 1040

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N   ++ AS     + +++E    +P V    ++       ++ + C   G P P ++W 
Sbjct: 1041 NSNGVTRAS----VWLLVRE----APQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWS 1092

Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575
            R+G+ L+  ++   + +               Y C A N+ G  E +  +     P ++ 
Sbjct: 1093 REGRALQEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSA 1152

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634
             N  +      G+E ++     G+PPP VIWY+       D E  +  ++  S ++RI  
Sbjct: 1153 VNGVVLAAK--GEEAVLECEATGVPPPRVIWYR------GDLEMILAPEDSISGMLRIPV 1204

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            ++   +  YT  A N  G +S E+ L+V   P   E P
Sbjct: 1205 VRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELP 1242



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 112/543 (20%), Positives = 195/543 (35%), Gaps = 43/543 (7%)

Query: 837  NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
            N   E+ V E   +  +      P P ITW+++ + + PS  +     G  ++L      
Sbjct: 2124 NETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQGS 2183

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSH- 954
               D+G Y C ASN+ G      R+ + V   +       +  +   G+ + LEC     
Sbjct: 2184 ---DAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVARGY 2240

Query: 955  -TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML--- 1010
               +  WYH    +  +D                       G+  C+        +L   
Sbjct: 2241 PPPTVSWYHEGLPV--VDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEAVLHYS 2298

Query: 1011 VVKETIPEFIRKL---QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK 1067
            V  +  P+ +      Q   +  + + +      S    + W ++G    P +       
Sbjct: 2299 VEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGH---PAEELPGVHV 2355

Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNK 1123
                  L+I +  +   G ++C   +E+ TA    E++V ELP  +I   +N        
Sbjct: 2356 TSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQP 2415

Query: 1124 ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE--- 1179
             T     T      +RW+KDG        + L   G    L+I   DL D G Y+C    
Sbjct: 2416 VTLRCAGTGVPTPSLRWWKDG--------VALAASGGS--LQIEKVDLKDEGTYTCVATN 2465

Query: 1180 -VGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237
              G S+   IL V   P+I   L     +   + T   L   +P    D++W+K +  I 
Sbjct: 2466 LAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLASGVPPP--DISWFKGRQPIS 2523

Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYER 1295
              ++  + +D   R L+I +    D   Y CV  +   +T+L+  + V  PP+I +    
Sbjct: 2524 AWDRAMVSTD--GRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSL 2581

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
               +   S V L  D    P P   W+ +   +         +      L +     +D+
Sbjct: 2582 PGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDS 2641

Query: 1356 GIY 1358
            G Y
Sbjct: 2642 GSY 2644



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 63/272 (23%), Positives = 108/272 (39%), Gaps = 23/272 (8%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP        + V E + + LEC    +P PDI+W FKG + +   + ++ + +D    
Sbjct: 2480 VPPNIEPGLVNKAVLENASVTLECLASGVPPPDISW-FKGRQPISAWDRAM-VSTDGR-- 2535

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGE 750
              VL I   +    G+Y  VA N  G   L   L++      PP++ + P     V    
Sbjct: 2536 --VLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNV----PPRITLPPSLPGPVLLHS 2589

Query: 751  SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTLKAE 808
             V L+    G P P + W K+  PV    T          + +L   +V D G Y+  A 
Sbjct: 2590 PVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAV 2649

Query: 809  NSEGIAETSAVITVEEPT----------EENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            ++ G      V+ V   +          E    PP  +   Q ++V    ++ L  R   
Sbjct: 2650 SAVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHA 2709

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIEL 890
             P P ++W ++   + P   +  + D   +E+
Sbjct: 2710 VPPPVLSWRKDGRPLEPRPGVYLSADKALLEV 2741



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 66/274 (24%), Positives = 110/274 (40%), Gaps = 22/274 (8%)

Query: 661  PEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
            P+P + W  KG    P  +   +A+  +  ++     + +V     G Y   A N  G A
Sbjct: 1815 PKPQVTWR-KGPSSEPLRDRPGLAVLDEGSLF-----LASVSPSDGGDYECQATNEAGSA 1868

Query: 720  SLPIVLKIKTGEKEPPQVIEPLKSMIVR--QGESVILSAQVVGNPRPTITWCKNNKPVKA 777
            S    L +      PP + E  +   V    G+S+ L     G P P ITW KN + + A
Sbjct: 1869 SRRAKLVVHV----PPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPA 1924

Query: 778  LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
            + +    D          +  D G+Y+ +AEN  G A+    + V  P        L   
Sbjct: 1925 VGSHRLLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPS-----VLGAE 1979

Query: 838  RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ-NFDGENIELVITNVD 896
              QE+        +L  R    P P + W ++ + +   E   Q   DG+ + +  +++ 
Sbjct: 1980 AAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLG 2039

Query: 897  SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
               D G Y+CVA + AG+ +   ++ I  E   F
Sbjct: 2040 ---DEGWYQCVAFSPAGQQTKDFQLRIHGEPSPF 2070



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 123/588 (20%), Positives = 217/588 (36%), Gaps = 62/588 (10%)

Query: 633  PPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
            PPT   S +     V EG  +   C    +P PDI W   G+ +VP   +          
Sbjct: 2117 PPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQ-- 2174

Query: 691  YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-----GEKEPPQVIEPLKSMI 745
                L++   +    GTY+  A N  G       L++       G  E P+V++ +    
Sbjct: 2175 ----LQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAV---- 2226

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
               G  + L     G P PT++W     PV        G    +  L+       G+Y+ 
Sbjct: 2227 --AGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGLYSC 2284

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A +  G A       +    E    P L +     ++T     ++ L    + +PVP+I
Sbjct: 2285 VASSPAGEA------VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTI 2338

Query: 865  TWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
             W +N     P+E +   +   E   L I +V+    +G + C A+N AG ++  A V +
Sbjct: 2339 QWLQNGH---PAEELPGVHVTSEGTTLHIDHVELG-HAGLFACQATNEAGTAA--AEVEL 2392

Query: 924  DVEKVTFVKHLQKSYETEEG-KTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980
             V ++  V  +     T    + V L C  +   T S +W+ +   ++       I++  
Sbjct: 2393 SVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQIEK-- 2450

Query: 981  XXXXXXXXXXXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILE 1037
                        D G   C+  +   E+   ++++  +P  I   L +  V E     LE
Sbjct: 2451 --------VDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLE 2502

Query: 1038 -VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             +       D+ W +  + I    ++      G  R L I    + D G Y C+  +   
Sbjct: 2503 CLASGVPPPDISWFKGRQPIS-AWDRAMVSTDG--RVLLIEQAQLSDAGSYRCVASNVVG 2559

Query: 1097 TAEVTV---VELPPEI-ITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNH 1151
            + E+     V +PP I +       V   +      +     + ++ W KDG+ +  +  
Sbjct: 2560 STELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGT 2619

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195
              L +    + L +    + D+G YSC     VG  +   +L V   S
Sbjct: 2620 AGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGEDRRDVVLRVHSES 2667



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 99/499 (19%), Positives = 181/499 (36%), Gaps = 39/499 (7%)

Query: 1279 LKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            L+ ++V  PP I   +   E  +  G  V  L + +  P P+  W  +   +     T+ 
Sbjct: 2109 LQRKLVTAPPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEV 2166

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNILEID 1393
                    L +++ + +DAG Y  +  N  G  +    + +   P+  G    P +++  
Sbjct: 2167 VYTRGGRQLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAV 2226

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFR 1452
            +                T+ +Y      +D    W+          S+++L   S   + 
Sbjct: 2227 AGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGV---LSLESLGEASGGLYS 2283

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A      S A E   +Y V  +   Q   V + L  +TT   + + L C   G P P 
Sbjct: 2284 CVAS-----SPAGEAVLHYSVEVQVAPQL-LVAEGLGQVTTLVGQSLYLPCYASGSPVPT 2337

Query: 1513 VTWYRDG---KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569
            + W ++G   ++L     T E                 + C A N+ G       + + +
Sbjct: 2338 IQWLQNGHPAEELPGVHVTSEG-TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHE 2396

Query: 1570 KP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
             P V+ +  E+I           +     G+P P + W+K+G          +       
Sbjct: 2397 LPSVVIVGGENITAPFL--QPVTLRCAGTGVPTPSLRWWKDG----------VALAASGG 2444

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688
             ++I+++       YT  A+N AG S  EV L+V   P+   G V    +   SVT+E  
Sbjct: 2445 SLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECL 2504

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                  G+     +  K     + W + A V  D     I++   +    +R +A N VG
Sbjct: 2505 A----SGVPPPDISWFKGRQPISAWDR-AMVSTDGRVLLIEQAQLSDAGSYRCVASNVVG 2559

Query: 1749 FSEALESEPIVIKTALDVP 1767
             +E   S  + +   + +P
Sbjct: 2560 STELQYSLRVNVPPRITLP 2578



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 517  RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
            R +    G  V+  C   GYP P I+W R+   ++     ++    D   TL+I+ V PE
Sbjct: 1065 RSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRV----DAQGTLIIQGVAPE 1120

Query: 577  DAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            DAG+++C A N  G    T  L    P S
Sbjct: 1121 DAGSYSCQAANEIGRDEETVTLYYTDPPS 1149



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            +G  V F C+  G P P ITWF+    + PS   ++ Y       L +      DAGT++
Sbjct: 2133 EGHPVWFLCEARGVPTPDITWFKDGDPLVPST--EVVYTRGG-RQLQLERAQGSDAGTYS 2189

Query: 583  CVAKNAAGFASSTTELIVEAPLSDHGS 609
            C A NA G    TT L V  P +  G+
Sbjct: 2190 CKASNAVGVVEKTTRLEVYVPPTIEGT 2216



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 6/169 (3%)

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVE 1285
            VTW K  S  E       ++ + + +L +   +  D  +Y C    +A S ++    VV 
Sbjct: 1819 VTWRKGPSS-EPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASRRAKLVVH 1877

Query: 1286 FPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
             PP + +  R   +    G  +TL  D   FP P   W+ N + I      +  +D   A
Sbjct: 1878 VPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHR-LLDGARA 1936

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392
             L   +++  D+G+Y  R EN  G A  + ++ +L  PS  G     E+
Sbjct: 1937 -LHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEV 1984



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580
            T +G      C   G P P ITW ++T  +  S+D   +Y+     TLVI     +DAG 
Sbjct: 1433 TNEGVPASLPCVASGVPTPTITWTKETNALA-SRD--PHYNVSKDGTLVIPRPSVQDAGA 1489

Query: 581  FTCVAKNAAGFASSTTELIV 600
            + C A NA GF+S    L V
Sbjct: 1490 YVCTATNAVGFSSQEMRLSV 1509



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 53/241 (21%), Positives = 100/241 (41%), Gaps = 18/241 (7%)

Query: 860  PVPSITWYR--NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
            P P +TW +  ++E +     +    +G    L + +V S  D GDY+C A+N AG +S 
Sbjct: 1815 PKPQVTWRKGPSSEPLRDRPGLAVLDEGS---LFLASV-SPSDGGDYECQATNEAGSASR 1870

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREI 975
             A++ + V         + +     G+++ LEC  +   + +  W  N ++I  +    +
Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRL 1930

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKD 1032
            +   R            D G+  C  ++Q  +        +   P  +      EV    
Sbjct: 1931 LDGAR--ALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLA 1988

Query: 1033 VAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             A  E+E   +   T  V W +DG+ +   + +   ++ G +  L I N+ + DEG Y C
Sbjct: 1989 GAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV--LRITNSHLGDEGWYQC 2046

Query: 1090 I 1090
            +
Sbjct: 2047 V 2047



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 23/198 (11%)

Query: 598  LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECR 656
            LI +A LSD GS   V            + +   +PP  +  P     V   S + L C 
Sbjct: 2538 LIEQAQLSDAGSYRCVASNVVGSTELQYS-LRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596

Query: 657  LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS--VLKITNVKKFQEGTYTVVAVN 714
                P P + WL  G  +      S A  + + ++    VL + + +    G+Y+ VAV+
Sbjct: 2597 AAGAPSPMLMWLKDGNPV------STAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVS 2650

Query: 715  REGEASLPIVLKIKT-------------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
              GE    +VL++ +              +  PP ++   +++ V   ESV L  +    
Sbjct: 2651 AVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHAV 2710

Query: 762  PRPTITWCKNNKPVKALP 779
            P P ++W K+ +P++  P
Sbjct: 2711 PPPVLSWRKDGRPLEPRP 2728



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 51/206 (24%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 749  GESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            G+S+       G P+P +TW K  +++P++  P  +  D  S+  L      D G Y  +
Sbjct: 1802 GKSLERDEGWAGTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSL-FLASVSPSDGGDYECQ 1860

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A N  G A   A + V  P     +      R   ++     ++ L       P P ITW
Sbjct: 1861 ATNEAGSASRRAKLVVHVPPSLRED-----GRRANVSGMAGQSLTLECDANGFPAPEITW 1915

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             +N   I P+    +  DG    L    +  E DSG Y C A N AG +     + + + 
Sbjct: 1916 LKNGRQI-PAVGSHRLLDGAR-ALHFPRI-QEGDSGLYSCRAENQAGTAQRDFDLLVLIP 1972

Query: 927  KVTFVKHLQKSYETEEGKTVILECQT 952
                     +      G    LEC+T
Sbjct: 1973 PSVLGAEAAQEVVGLAGAGAELECRT 1998



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 21/195 (10%)

Query: 626  ADILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
            A ++  +PP+  +  +   V    G  + LEC     P P+I WL  G +I P       
Sbjct: 1872 AKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQI-PAVGSHRL 1930

Query: 684  IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPL 741
            ++         L    +++   G Y+  A N+ G A     L +      PP V+  E  
Sbjct: 1931 LDG-----ARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLI----PPSVLGAEAA 1981

Query: 742  KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKV 797
            + ++   G    L  + +G P P + W K+ +PV      +  + DG    IT      +
Sbjct: 1982 QEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRIT---NSHL 2038

Query: 798  KDEGVYTLKAENSEG 812
             DEG Y   A +  G
Sbjct: 2039 GDEGWYQCVAFSPAG 2053



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G ++  EC   G+P P+ITW +    I      ++    D    L    +   D+G ++C
Sbjct: 1896 GQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLL---DGARALHFPRIQEGDSGLYSC 1952

Query: 584  VAKNAAGFASSTTELIVEAPLSDHGSE 610
             A+N AG A    +L+V  P S  G+E
Sbjct: 1953 RAENQAGTAQRDFDLLVLIPPSVLGAE 1979



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 33/166 (19%), Positives = 58/166 (34%), Gaps = 5/166 (3%)

Query: 1505 FGGVPQPKVTWYR--DGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            + G P+P+VTW +    + L+        +                Y+C A N+ G    
Sbjct: 1811 WAGTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASR 1870

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
               + +   P +             G    +     G P PE+ W KNG ++     + +
Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRL 1930

Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
               +    +    ++   S  Y+  A N AGT+  +  L V   PS
Sbjct: 1931 L--DGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPS 1974



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 37/186 (19%), Positives = 71/186 (38%), Gaps = 4/186 (2%)

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXXXXXXXXXX 1547
            N++    + + L C   G P P++TW ++G+++    +    +                 
Sbjct: 1890 NVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEGDSGL 1949

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607
            Y C A N  G  +    + +   P +  +    +     G    +     G+P P+V W 
Sbjct: 1950 YSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWT 2009

Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            K+G  +    E  +  +E   V+RI          Y   A + AG  + +  L+++ +PS
Sbjct: 2010 KDGQPVFLG-EPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHGEPS 2068

Query: 1668 K-PEGP 1672
              P  P
Sbjct: 2069 PFPSSP 2074



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 523  DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            + ++V  EC   G P P I+WF+    I  + D  M   D  V  L+I +    DAG++ 
Sbjct: 2495 ENASVTLECLASGVPPPDISWFKGRQPIS-AWDRAMVSTDGRV--LLIEQAQLSDAGSYR 2551

Query: 583  CVAKNAAGFASSTTELIVEAP 603
            CVA N  G       L V  P
Sbjct: 2552 CVASNVVGSTELQYSLRVNVP 2572



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 2/71 (2%)

Query: 535  GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
            G P+PQ+TW R+    +P +D       D   +L +  V P D G + C A N AG AS 
Sbjct: 1813 GTPKPQVTW-RKGPSSEPLRDRPGLAVLDE-GSLFLASVSPSDGGDYECQATNEAGSASR 1870

Query: 595  TTELIVEAPLS 605
              +L+V  P S
Sbjct: 1871 RAKLVVHVPPS 1881



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G  V  +C+ +G P P +TW + +  + P  D           +L + +    D+G + C
Sbjct: 1534 GDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPP---GSLHLAQAQVSDSGLYEC 1590

Query: 584  VAKNAAGFASSTTELIVEAP 603
             A N AG A+    L V+ P
Sbjct: 1591 TASNPAGSATQYYILRVQVP 1610



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 5/78 (6%)

Query: 527  VQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
            V   C V  G PRP+  W +    + P     +  D     +L + +   EDAG ++CV 
Sbjct: 1348 VSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRAD----GSLHLDQALLEDAGRYSCVV 1403

Query: 586  KNAAGFASSTTELIVEAP 603
             N AG      +L+V+ P
Sbjct: 1404 SNTAGSHHRDVQLVVQVP 1421



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 5/100 (5%)

Query: 503  SEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
            S E  +AP  +  E L    T  G ++   C   G P P I W +      P+++    +
Sbjct: 2298 SVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNG---HPAEELPGVH 2354

Query: 561  DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                  TL I  V    AG F C A N AG A++  EL V
Sbjct: 2355 VTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSV 2394



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 7/99 (7%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR---QTAIIKPSQDFQMYYD 561
            E   AP  +E  +      G +    C+  G+P P ITW R   Q   ++P    +  + 
Sbjct: 1231 EVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGS--RTGWP 1288

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            D  V  L    V PED   + C A+N  G   +   L+V
Sbjct: 1289 DSGV--LFFESVVPEDQALYVCEAENVFGKVQAEAYLLV 1325



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 9/103 (8%)

Query: 490  EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
            EK  +L V+  PT E     P  V+ +       G  +  EC   GYP P ++W+ +   
Sbjct: 2200 EKTTRLEVYVPPTIEGTGEGPRVVKAVA------GRPLTLECVARGYPPPTVSWYHEGL- 2252

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
              P  D    +       L +  +     G ++CVA + AG A
Sbjct: 2253 --PVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 2293



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-DDDNVATLV-IREVFPEDAGTF 581
            G     EC+  G P P++ W+R         D +M    +D+++ ++ I  V   DAG +
Sbjct: 1162 GEEAVLECEATGVPPPRVIWYR--------GDLEMILAPEDSISGMLRIPVVRERDAGVY 1213

Query: 582  TCVAKNAAGFASSTTELIV 600
            TC A N  G AS+   L V
Sbjct: 1214 TCRAVNELGDASAEIRLEV 1232


>UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 457

 Score =  110 bits (264), Expect = 5e-22
 Identities = 92/396 (23%), Positives = 165/396 (41%), Gaps = 24/396 (6%)

Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
           ++L +     + +    P FV   + K   +G +V FEC  +G P P +TW +  + +  
Sbjct: 71  NELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNT 130

Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE----LIVEAPLSDHG 608
           S D + Y    N   L+I  V   D+G + C A +  G  +   E    +I     +D  
Sbjct: 131 SVDPRFY---SNGTHLMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEA 187

Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAW 667
           S                 ++    PP F +  K  + ++E  ++ L C+L   P   + W
Sbjct: 188 SYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVW 247

Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
           L    E+ PD  + +   S +    S L I NV +  E  Y  +A N     +      +
Sbjct: 248 LKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 307

Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK------ 781
               + PP+  +  K+  V +  +V L+ Q+   P+ ++TW K+N P+   P +      
Sbjct: 308 VV--QYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHP 365

Query: 782 -SDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF 839
            S G+T S   +      DE  Y+ KA N+ G  +    ++TV  P +      L I + 
Sbjct: 366 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKF-----LEILKA 420

Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
           +E+   E   + L  ++   P+ ++ W ++N  + P
Sbjct: 421 EEMR-NETDNLTLTCKLEGKPLATVLWLKDNTELEP 455



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 84/347 (24%), Positives = 139/347 (40%), Gaps = 47/347 (13%)

Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
           +PK +   EG  +  EC+    P P++ WL  G        ++ +++   +   ++L IT
Sbjct: 2   EPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSA------VNTSVDPRFYSNDTILMIT 55

Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
           NV +   GTY+  A N  G  S    L ++ G    P+ +   +     +G SV      
Sbjct: 56  NVSRIDSGTYSCNASNELGIISAEAALDVRYG----PEFVNVPQDKTPNEGWSVTFECHT 111

Query: 759 VGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAEN-----SE 811
            GNP PT+TW KN   +     P      TH + I    +  D G Y   A +     ++
Sbjct: 112 KGNPPPTVTWLKNGSALNTSVDPRFYSNGTH-LMITNVNRT-DSGAYRCNASSILGPEND 169

Query: 812 GIAETSAVITVEEPTEE--------NAE--------------PPLFINRFQ-EITVKEKG 848
           G   +  +I+    T+E        NA               PP F+   + E T+ E  
Sbjct: 170 GNETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETD 229

Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQ--NFDGENIELVITNVDSEIDSGDY 904
            + L  ++   P+ ++ W ++N  + P     ITQ  + D     L I NV    D   Y
Sbjct: 230 NLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH-DEAYY 288

Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
           KC+A+N+   ++     ++ V+         K+    E   V L CQ
Sbjct: 289 KCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQ 335



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 89/362 (24%), Positives = 147/362 (40%), Gaps = 58/362 (16%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F   P+ +  +EG  +  EC     P P + WL  G        ++ +++   +   +
Sbjct: 88  PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSA------LNTSVDPRFYSNGT 141

Query: 694 VLKITNVKKFQEGTYTVVA--------------------VNREGEASLPIVLKIKTGEKE 733
            L ITNV +   G Y   A                    +NR  EAS     K   GEK 
Sbjct: 142 HLMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKT 201

Query: 734 ----------PPQVIEPLKSM-IVRQGESVILSAQVVGNPRPTITWCKNN---KPVKAL- 778
                     PP+ ++ LK    + + +++ L+ ++ G P  T+ W K+N   +P   L 
Sbjct: 202 SGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLI 261

Query: 779 ---PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
              P+  D    ++TI+   +  DE  Y   A N+    +T+   T      +   PP F
Sbjct: 262 ITQPSSVDSGESTLTIINVHR-HDEAYYKCLANNT---VDTTTSTTNTSVVVQY--PPKF 315

Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---TITQ--NFDGENIEL 890
               +  TV EK  + L  ++   P  S+TW ++N  +  S    T+T   ++      L
Sbjct: 316 FQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSL 375

Query: 891 VITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949
            ITN+    D   Y C A N+AG KSS    +T++     F++ L+      E   + L 
Sbjct: 376 TITNL-VRTDEARYSCKAINAAGEKSSEQGLLTVNYPP-KFLEILKAEEMRNETDNLTLT 433

Query: 950 CQ 951
           C+
Sbjct: 434 CK 435



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 3/82 (3%)

Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
           K T +G  V+FECQ  G P P +TW +  + +  S D   +Y +D +  L+I  V   D+
Sbjct: 6   KTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVD-PRFYSNDTI--LMITNVSRIDS 62

Query: 579 GTFTCVAKNAAGFASSTTELIV 600
           GT++C A N  G  S+   L V
Sbjct: 63  GTYSCNASNELGIISAEAALDV 84



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 91/373 (24%), Positives = 147/373 (39%), Gaps = 61/373 (16%)

Query: 1074 LYIRNTSVHDEGEYSCILRDES--CTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIEL 1130
            L I N S  D G YSC   +E    +AE  + V   PE +   Q++  N+G   TFE   
Sbjct: 52   LMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECH- 110

Query: 1131 TKGDA--LVRWFKDGSEIQ-------FSN--HIQLTI---------------------DG 1158
            TKG+    V W K+GS +        +SN  H+ +T                      DG
Sbjct: 111  TKGNPPPTVTWLKNGSALNTSVDPRFYSNGTHLMITNVNRTDSGAYRCNASSILGPENDG 170

Query: 1159 KKQK-LKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANT 1212
             +   L I + +  D   Y+C   N+       +  L V  P   F   L +   +    
Sbjct: 171  NETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPP-KFLQSLKDEETLNETD 229

Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLIS----DVKKRTLIIRKCTEDDQCEYT 1267
            +  LT ++  + L  V W K  + +E   +  +      D  + TL I      D+  Y 
Sbjct: 230  NLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYK 289

Query: 1268 CVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
            C+    +D  ++T     VV++PPK     +   +   S+VTL    +  P+ +  W+ +
Sbjct: 290  CLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKD 349

Query: 1325 SKII----KKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +  +     +   T P S  + ++SLTI  +  TD   Y  +  N  G    E  +  ++
Sbjct: 350  NTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN 409

Query: 1380 KPSPPGKPNILEI 1392
             P     P  LEI
Sbjct: 410  YP-----PKFLEI 417



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 41/168 (24%), Positives = 64/168 (38%), Gaps = 10/168 (5%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXX 1546
            K  TT   + ++  C   G P P VTW + G  + T+     Y N               
Sbjct: 4    KGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYSNDTILMITNVSRIDSG 63

Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEV 1604
             Y C A N+ G +     + ++  P       ++ Q     + W VT     +G PPP V
Sbjct: 64   TYSCNASNELGIISAEAALDVRYGPEFV----NVPQDKTPNEGWSVTFECHTKGNPPPTV 119

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             W KNG+ L    +    +    + + I  + R+ S  Y   AS+  G
Sbjct: 120  TWLKNGSALNTSVDPRFYS--NGTHLMITNVNRTDSGAYRCNASSILG 165



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 95/438 (21%), Positives = 155/438 (35%), Gaps = 55/438 (12%)

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
            +VTW K  S +  +      S+     L+I   +  D   Y+C   +       +  + V
Sbjct: 27   NVTWLKSGSAVNTSVDPRFYSN--DTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 84

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
             + P+ V+  ++     G  VT     +  P P   W+ N   +       P   S    
Sbjct: 85   RYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALN--TSVDPRFYSNGTH 142

Query: 1345 LTIKKVENTDAGIYK------LRLENNCGHADVEM--NVTILDKPSPP--GKPNILEIDS 1394
            L I  V  TD+G Y+      L  EN+       M  N+   D+ S     K    E  S
Sbjct: 143  LMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKTS 202

Query: 1395 SSINICWDEP---------ENTGNST---IIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
             S+N+  + P         E T N T    +   +E + + T  W+  K+ T+ +   + 
Sbjct: 203  GSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWL--KDNTELEPDSRL 260

Query: 1443 LKTN-SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--------VEKP------ 1487
            + T  SS       +  +++    E   YYK +    + + T        V+ P      
Sbjct: 261  IITQPSSVDSGESTLTIINVHRHDEA--YYKCLANNTVDTTTSTTNTSVVVQYPPKFFQS 318

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--------KATYENRXXX-XXX 1538
             KN T     ++ LTC     P+  VTW +D   L T+          +Y N        
Sbjct: 319  PKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTIT 378

Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                     Y C A N  GE  +   +     P   +     ++     D   +T  +EG
Sbjct: 379  NLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLEILKAEEMRNETDNLTLTCKLEG 438

Query: 1599 IPPPEVIWYKNGNKLEND 1616
             P   V+W K+  +LE D
Sbjct: 439  KPLATVLWLKDNTELEPD 456



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 21/194 (10%)

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-------TAKATYEN-RXXXXXXXXXXX 1543
            T    +++ LTC   G P   V W +D  +L+       T  ++ ++             
Sbjct: 224  TLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH 283

Query: 1544 XXXXYKCIAFN--DHGEVETSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGI 1599
                YKC+A N  D     T+  V +Q  P    S  NE + +K  V     +T  +E  
Sbjct: 284  DEAYYKCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNV----TLTCQLECK 339

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTK-----EKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            P   V W K+   L+   +    T        TS + I  L R+  ++Y+ +A N AG  
Sbjct: 340  PKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEK 399

Query: 1655 SVEVTLKVYDKPSK 1668
            S E  L   + P K
Sbjct: 400  SSEQGLLTVNYPPK 413



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 7/127 (5%)

Query: 1548 YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606
            Y C A N  GE  +  V + +   P    S +D +  ++  D   +T  +EG P   V+W
Sbjct: 189  YTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNET-DNLTLTCKLEGKPLATVVW 247

Query: 1607 YKNGNKLENDKEYNITTKEKT----SVIRIKELKRSHSSKYTIEASNTAG-TSSVEVTLK 1661
             K+  +LE D    IT         S + I  + R   + Y   A+NT   T+S   T  
Sbjct: 248  LKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 307

Query: 1662 VYDKPSK 1668
            V   P K
Sbjct: 308  VVQYPPK 314


>UniRef50_Q62234 Cluster: Myomesin-1; n=32; cellular organisms|Rep:
            Myomesin-1 - Mus musculus (Mouse)
          Length = 1666

 Score =  109 bits (263), Expect = 6e-22
 Identities = 106/461 (22%), Positives = 189/461 (40%), Gaps = 23/461 (4%)

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKP 1669
            EN +  N     K+    + +L    S ++ +  SN+AG    + + EVT+ V DK   P
Sbjct: 660  ENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTV-VGDKLDIP 718

Query: 1670 EGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
            + P  +I    +  SV + W+   D    EL  Y IE     + +W    +       + 
Sbjct: 719  KAPGKIIPSRNTDTSVVVSWEESRD--AKELVGYYIEASVVGSGKWEPCNNNPVKGSRFT 776

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
               L     Y+FRV A N  G SE + +SE I +K A+              + +    +
Sbjct: 777  CHGLTTAQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVWPQLSDTPGGL 833

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
            T      NG SP    K  +                  + +  +++ + Q  + +  +  
Sbjct: 834  TDSRGGMNGASPPTSQKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEA 893

Query: 1847 TSLPYTSDDKITIGKT--LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904
                  S  +    K   +  PS P +    ES   S+ L W +P++ GG+ IT Y + +
Sbjct: 894  APEEEQSQSEPPKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNY 953

Query: 1905 KTVKGK---SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TESQSVRLE 1960
            + V G+    W +      S   + I N+KE     F++SA N  G+  P T S+  + E
Sbjct: 954  REVVGEVPGKWREANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCE 1013

Query: 1961 KHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT--KTMWMEVG 2017
            +    VP PP + +++  V  N ++  W  P + G  P+ GY + +++ +     W  + 
Sbjct: 1014 EWTIAVPGPPHS-VKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLN 1072

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
            +  +      ++ L E   Y+ R+ A N+ G+ +P +   P
Sbjct: 1073 EAAIVNKYLRVQGLKEGTCYVFRVRAVNQAGVGKPSDLAGP 1113



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 101/407 (24%), Positives = 160/407 (39%), Gaps = 29/407 (7%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727
            P   + + E +R  V + WKPP    G E   Y +EK +     W +V  ++      + 
Sbjct: 619  PPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCDVGAENWQRVNTELPVKSPRFA 677

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L E   Y FRV   N  G  E  E +E  V+   LD+P            D  SV +
Sbjct: 678  LFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDT-SVVV 736

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINT--TYQFRIYARN 1843
            +W   E      ++ Y +E    G  KW+         +R     + T  +Y FR+ A N
Sbjct: 737  SW--EESRDAKELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVN 794

Query: 1844 EIGTSLPYTSDD-----KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898
              G S  Y+ D      K  IG  ++P   P+   +S++      L  +    NG SP T
Sbjct: 795  AAGLS-EYSQDSEAIEVKAAIGGGVSPDVWPQ---LSDTPG---GLTDSRGGMNGASPPT 847

Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
            +   +   + G +  K             E     + +   +S+          +SQS  
Sbjct: 848  S---QKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEAAPEEEQSQSEP 904

Query: 1959 LEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM---W 2013
             +K     + P+AP +I  + S  + ++  W  P+  GGA + GY +  R+V   +   W
Sbjct: 905  PKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKW 964

Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             E     V+   + I +L EN  Y  ++ A N  GL  P    E FK
Sbjct: 965  REANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFK 1011



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 57/239 (23%), Positives = 97/239 (40%), Gaps = 33/239 (13%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P+ P + V  ++    + + W +P  +GGSPI  Y I+   V   +W++           
Sbjct: 489  PAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARF 548

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE----------SQSVRLEKH------------- 1962
             +  + E    IFR+ A N  G+ LP+           ++  RL+ H             
Sbjct: 549  PVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHPSAPWTGQIIVTE 608

Query: 1963 -----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
                   +P PPT  L +     + V+ SW  P   G   ++ Y +   DV    W  V 
Sbjct: 609  EEPTEGVIPGPPT-DLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCDVGAENWQRVN 666

Query: 2018 -KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075
             ++ V + +F + DL E  +Y  R+   N  G+ EP E+ E    + G+     + PG+
Sbjct: 667  TELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTE--VTVVGDKLDIPKAPGK 723



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 51/198 (25%), Positives = 82/198 (41%), Gaps = 6/198 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHE 1924
            P  P +  V+E+T   V L W  P   G   I  Y +E   V  ++W ++ T +      
Sbjct: 617  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCDVGAENWQRVNTELPVKSPR 675

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIV 1983
              + ++ E     FR+   N+ GV  P+E+  V  +     +P  P   +  R   +++V
Sbjct: 676  FALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 735

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
            + SW   E      L+GY I    V    W       V   +F    L+   +Y+ R+ A
Sbjct: 736  V-SW--EESRDAKELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRA 792

Query: 2044 RNEIGLSEPLESDEPFKV 2061
             N  GLSE  +  E  +V
Sbjct: 793  VNAAGLSEYSQDSEAIEV 810



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 3/114 (2%)

Query: 1963 ATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
            A +   P APL++  + +N   ++ SW  P  DGG+P+LGY I   +V    W +     
Sbjct: 483  AEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTP 542

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI-PGEGSHADEEP 2073
            V   +F +  L E  +Y+ R+ A N+ G+  P    EP   + P E +     P
Sbjct: 543  VKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHP 596



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 7/164 (4%)

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            PEV WY+NG  +   K          + +    L +     YTI              + 
Sbjct: 418  PEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 477

Query: 1662 VYDKPSKPEGP------VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715
            V D  ++ EG       V+  + +++ + I WK P  DGG  +  Y I+K E   + W +
Sbjct: 478  VRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQ 537

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPI 1758
              D       + +  L E   Y+FRV A N  G    +  SEP+
Sbjct: 538  CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPV 581



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 13/201 (6%)

Query: 1280 KVEVVEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337
            KVE+  F  K  V + RE   +  G  V +  + + F QP  +W  N   +   K  +P 
Sbjct: 381  KVEI-HFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEVQWYRNGAPVSPSKWVQPH 438

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-----KPSPPGKPNILEI 1392
                 A+LT   +   D G+Y +R+     +      V + D     + +P    +++ +
Sbjct: 439  WSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSL 498

Query: 1393 DSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSS 1448
            D++   I I W +P   G S I+ Y ++  E+ T  W    +  +   +  +  L    S
Sbjct: 499  DANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGRS 558

Query: 1449 YRFRAYAVNEVDISDASETTE 1469
            Y FR  AVN+  I   S  +E
Sbjct: 559  YIFRVRAVNKTGIGLPSRVSE 579



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 49/232 (21%), Positives = 90/232 (38%), Gaps = 13/232 (5%)

Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           L + +++   +    +E+  + AP F+ K R     +   V+  C V G+P P++TW++ 
Sbjct: 234 LKKTLEETQTYHGKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKN 293

Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
              I    +   Y  +    + TL I +   ED   +   A N  G  S+   ++V+   
Sbjct: 294 QVPINVHANPGKYIIESRYGMHTLEISKCDFEDTAQYRASAMNVQGELSAYASVVVKRYK 353

Query: 605 SD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE- 662
            +   S +                    +   F  K    +  EG  + L CR+V  PE 
Sbjct: 354 GELDESLLRGGVSMPLSFAVTPYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEI 413

Query: 663 ----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
               P++ W   G  + P + +      D     + L  +++ K  EG YT+
Sbjct: 414 KHFQPEVQWYRNGAPVSPSKWVQPHWSGDR----ATLTFSHLNKEDEGLYTI 461



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEW--ISVKNITK 1435
            PS P     LE    S+ + W +P+ TG + I  Y V Y+E+      +W   ++K ++ 
Sbjct: 915  PSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKWREANIKAVSD 974

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
                I NLK N+ Y+F+  A+N   +   S  +E +K
Sbjct: 975  AAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFK 1011



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 9/141 (6%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGP---VIMREISRESVT 1684
            +I  LK +   ++ + A N AG    S+V    K  +      GP   V + E+ + S+ 
Sbjct: 978  KISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCEEWTIAVPGPPHSVKLSEVRKNSLV 1037

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            ++WKPP+  G   +T Y ++  E    +++W  + +     +   +Q L E   Y+FRV 
Sbjct: 1038 LQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNKYLRVQGLKEGTCYVFRVR 1097

Query: 1743 AQNPVGFSEALE-SEPIVIKT 1762
            A N  G  +  + + P+V +T
Sbjct: 1098 AVNQAGVGKPSDLAGPVVAET 1118



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 5/117 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P PP   ++ E   S + + W  P   G+  I+Y+ VE  ++    W  V     +   +
Sbjct: 617  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEKCDVGAENWQRVNTELPVKSPR 675

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITT 1493
             ++ +L    SYRFR    N   + + SETTE   V  +  I ++P    P +N  T
Sbjct: 676  FALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDT 732



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 68/332 (20%), Positives = 128/332 (38%), Gaps = 25/332 (7%)

Query: 506  QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDN 564
            +   P F E L  + T +   V  +C+V    +   I W++    I   +        D 
Sbjct: 1335 RKQGPHFAEYLSWEVTGE-CNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDG 1390

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---PLSDHGSEMTVXXXXXXXX 621
            + TL+I E   +DAG +  + K+  G   S  +L+ EA    +++   ++ +        
Sbjct: 1391 ICTLLITEFSKKDAGFYEVILKDDRGKDKSRLKLVDEAFQDLMTEVCKKIALSATDLKIQ 1450

Query: 622  XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681
                   L      +    K  +   G+ I    R+ +    +  WL   E   P  N  
Sbjct: 1451 STAEGIRLYSFVCYYLDDLKVNWSHNGTGIKYTDRVKSGVTGEQIWLQINE---PTPN-- 1505

Query: 682  VAIESDMHMYCSVLKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEP 740
                 D   Y  V+++ + K   + T  +      E  A    + +    EK   +V+  
Sbjct: 1506 -----DKGKY--VMELFDGKTGHQKTVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGG 1558

Query: 741  LKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796
            L  ++ +++G+++ L+  V G+P P ++W KN KP+ +      K +    +   +    
Sbjct: 1559 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVS 1618

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
              D G Y L  +N  G   +   ++V  P EE
Sbjct: 1619 TADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1650



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 57/206 (27%), Positives = 85/206 (41%), Gaps = 38/206 (18%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTK----SDGDTH 787
           P  +I+P +S  V + E+V L   V G P P +TW KN  P+   A P K    S    H
Sbjct: 257 PEFIIKP-RSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH 315

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP--------PL----- 834
           ++ I K    +D   Y   A N +G     A + V+    E  E         PL     
Sbjct: 316 TLEISKCD-FEDTAQYRASAMNVQGELSAYASVVVKRYKGELDESLLRGGVSMPLSFAVT 374

Query: 835 -----------FINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSET 878
                      F ++F     +E  T+ L  RV   P      P + WYRN   +SPS+ 
Sbjct: 375 PYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGAPVSPSKW 434

Query: 879 ITQNFDGENIELVITNVDSEIDSGDY 904
           +  ++ G+   L  ++++ E D G Y
Sbjct: 435 VQPHWSGDRATLTFSHLNKE-DEGLY 459



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 60/231 (25%), Positives = 92/231 (39%), Gaps = 39/231 (16%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS-VAIESDMHMYC 692
           P F  KP++  V E  ++ L C +   PEP + W      I    N     IES   M+ 
Sbjct: 257 PEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH- 315

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASL--PIVLKIKTGEKEPPQ----VIEPLKSMIV 746
             L+I+         Y   A+N +GE S    +V+K   GE +       V  PL   + 
Sbjct: 316 -TLEISKCDFEDTAQYRASAMNVQGELSAYASVVVKRYKGELDESLLRGGVSMPLSFAVT 374

Query: 747 ---------------------RQGESVILSAQVVGNP-----RPTITWCKNNKPV---KA 777
                                R+GE++ L  +VV  P     +P + W +N  PV   K 
Sbjct: 375 PYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGAPVSPSKW 434

Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
           +     GD  ++T     K +DEG+YT++    E   + SA + V +   E
Sbjct: 435 VQPHWSGDRATLTFSHLNK-EDEGLYTIRVRMGEYYEQYSAYVFVRDADAE 484



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 6/102 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN--ITKT 1436
            P PP    + E+  +S+ + W  P  +G + +  Y V+ +E    +  W  +    I   
Sbjct: 1020 PGPPHSVKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNK 1079

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
               +Q LK  + Y FR  AVN+  +   S+      V+ ET+
Sbjct: 1080 YLRVQGLKEGTCYVFRVRAVNQAGVGKPSDLAG--PVVAETR 1119



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650
            +T  + G PPPEV W KN   L +D   ++  +  KT+   I  +  + S KY +   N 
Sbjct: 1573 LTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNK 1632

Query: 1651 AGTSSVEVTLKVY 1663
             G+ + + T+ V+
Sbjct: 1633 YGSETSDFTVSVF 1645



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R  N+ G  +      VT+    LD P  PGK        +S+ + W+E  +     
Sbjct: 689  FRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESRDA--KE 746

Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            ++ Y +E   + + +W    N  +  ++ +   L T  SY FR  AVN   +S+ S+ +E
Sbjct: 747  LVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVNAAGLSEYSQDSE 806

Query: 1470 YYKV 1473
              +V
Sbjct: 807  AIEV 810



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 6/95 (6%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETITQNFDGENI 888
           P FI + +  TV EK  +KL   V   P P +TWY+N    N   +P + I ++  G + 
Sbjct: 257 PEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH- 315

Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            L I+  D E D+  Y+  A N  G+ S  A V +
Sbjct: 316 TLEISKCDFE-DTAQYRASAMNVQGELSAYASVVV 349



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GENIELVITNVDSEID 900
            +T++E   + L   V  +P P ++W +N + ++  +  +  F+ G+     I+ V S  D
Sbjct: 1563 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGV-STAD 1621

Query: 901  SGDYKCVASNSAGKSSHGARVTI 923
            SG Y  V  N  G  +    V++
Sbjct: 1622 SGKYGLVVKNKYGSETSDFTVSV 1644


>UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gallus
           gallus|Rep: Neurofascin precursor. - Gallus gallus
          Length = 1249

 Score =  109 bits (262), Expect = 8e-22
 Identities = 80/319 (25%), Positives = 144/319 (45%), Gaps = 22/319 (6%)

Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
           +Q V  G D+LLEC    +P PDI W  KG E+        A ++ +  +   L+I+NV 
Sbjct: 271 SQMVLRGVDLLLECIASGVPAPDIMWYKKGGELP-------AGKTKLENFNKALRISNVS 323

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           +   G Y  +A N+ G     I +++K      P  ++  +++I+  GE   L  +  GN
Sbjct: 324 EEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEPQNLILAPGEDGRLVCRANGN 379

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENSEGIAETSAVI 820
           P+P+I W  N +P++  P     +    TI+ +  ++    VY   A N  G    +A +
Sbjct: 380 PKPSIQWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFV 439

Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
           +V +       P +   R Q I V +    +L      +P+P++ W++N +         
Sbjct: 440 SVLD-----VPPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNY 494

Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
           +  +  ++E+ +   +   D G Y CVA+N  GK    A+V ++V+  T +    +    
Sbjct: 495 KAHENGSLEMSMARKE---DQGIYTCVATNILGKVE--AQVRLEVKDPTRIVRGPEDQVV 549

Query: 941 EEGKTVILECQTSHTVSTK 959
           + G    L C+  H  + K
Sbjct: 550 KRGSMPRLHCRVKHDPTLK 568



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 77/295 (26%), Positives = 122/295 (41%), Gaps = 27/295 (9%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMHMYC 692
           P +  +P+   +  G D  L CR    P+P I WL  GE I     N S  +  D  ++ 
Sbjct: 353 PYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPPNPSREVAGDTIVF- 411

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751
                   +  Q G+  V   N   E    +     +    PP+++ P   +I V Q   
Sbjct: 412 --------RDTQIGSSAVYQCNASNEHGYLLANAFVSVLDVPPRILAPRNQLIKVIQYNR 463

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             L     G+P PT+ W KN +             +    +   + +D+G+YT  A N  
Sbjct: 464 TRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEMSMARKEDQGIYTCVATNIL 523

Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI-KLVARVTRNPV--PSITWYR 868
           G  E    + V++PT         I R  E  V ++G++ +L  RV  +P    ++TW +
Sbjct: 524 GKVEAQVRLEVKDPTR--------IVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLK 575

Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++  +     + +  DG    L I  V +E D GDY CVAS    K S  A +T+
Sbjct: 576 DDAPLYIGNRMKKEDDG----LTIYGV-AEKDQGDYTCVASTELDKDSAKAYLTV 625



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 162/814 (19%), Positives = 294/814 (36%), Gaps = 63/814 (7%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + RG D+ L       P P+  W      +   K TK  +++ + +L I  V   D+G Y
Sbjct: 274  VLRGVDLLLECIASGVPAPDIMWYKKGGELPAGK-TK--LENFNKALRISNVSEEDSGEY 330

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYV 1416
                 N  G     ++V +   P    +P   IL        +C     N      I ++
Sbjct: 331  FCLASNKMGSIRHTISVRVKAAPYWLDEPQNLILAPGEDGRLVC---RANGNPKPSIQWL 387

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            V  + I+ +     + +       ++ +  SS  ++  A NE     A+       V   
Sbjct: 388  VNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDV--P 445

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXX 1534
             +I +P   + +K I         L C F G P P + W+++G+        Y+      
Sbjct: 446  PRILAPR-NQLIKVIQYNRTR---LDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGS 501

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y C+A N  G+VE    + ++    I    ED  Q  K G    +  
Sbjct: 502  LEMSMARKEDQGIYTCVATNILGKVEAQVRLEVKDPTRIVRGPED--QVVKRGSMPRLHC 559

Query: 1595 VIEGIPPPE--VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
             ++  P  +  V W K+   L          K++   + I  +       YT  AS    
Sbjct: 560  RVKHDPTLKLTVTWLKDDAPLYIGNRM----KKEDDGLTIYGVAEKDQGDYTCVASTELD 615

Query: 1653 TSSVEVTLKVY-------DKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
              S +  L V        +KP +P+ P  + + +++  SV + W P  DD    +T Y +
Sbjct: 616  KDSAKAYLTVLALPITPAEKPERPDRPRDLELSDLAERSVKLTWIPG-DDNNSPITDYIV 674

Query: 1704 EKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVI 1760
            +  E       W   +    +V +  +  L+    Y FRVIA N VG S  ++ SE    
Sbjct: 675  QFEEDRFQPGTWHNHSRYPGNVNS-ALLSLSPYVNYQFRVIAVNDVGSSLPSMPSER--Y 731

Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVEIKQEGKK--WKXXX 1817
            +T+   P               ++ ITW P +      P + Y V  ++   +  W    
Sbjct: 732  QTSGARPEINPTGVQGAGTQKNNMEITWTPLNATQAYGPNLRYIVRWRRRDPRGSWYNET 791

Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
                    +    I   Y+ ++ A N+ G + P   +  I       P + P +  +   
Sbjct: 792  VKAPRHV-VWNTPIYVPYEIKVQAENDFGRA-P-EPETYIGYSGEDYPKAAPTDVRIRVL 848

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE-I 1936
             S ++ L WT    +    I   + E++    +  + +  +  S     +    +++  I
Sbjct: 849  NSTAIALTWTRVHLD---TIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGI 905

Query: 1937 IFRISAENTVGVSLPT-----ESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGT 1989
            + R+   +   + +       +     +++  T    P++P  L IR      +   W  
Sbjct: 906  VSRLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRYLRIRQPNLESINLEWDH 965

Query: 1990 PEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
            PE   G  L GYN+  +  + +KT    V     N  +F ++       Y   + AR ++
Sbjct: 966  PEHPNGV-LTGYNLRYQAFNGSKTGRTLVENFSPNQTRFTVQRTDPISRYRFFLRARTQV 1024

Query: 2048 GLSEPLESDEPFKVIPGEG---SHADEEPGEQTE 2078
            G  E +  + P  +  G G      D+  G +TE
Sbjct: 1025 GDGEVIVEESPALLNEGFGFPEPQLDKGRGNKTE 1058



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 82/417 (19%), Positives = 161/417 (38%), Gaps = 35/417 (8%)

Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
            PP I     ++Y +    ++ +  + +  P P   W  N K     K  K S+  +S +L
Sbjct: 39   PPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTL 98

Query: 1346 TIK-----KVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPS-PPGKPNILEIDSSS-I 1397
             I      + ++ + G Y+    N+ G A   ++++ +   P  P  K +++E+D  + +
Sbjct: 99   VIDFHGGGRPDDYE-GEYQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPL 157

Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNSSYRFRAY 1454
            ++  + P       I +     + I   + +S     ++  +   +Q+ +T+ S   R +
Sbjct: 158  SLQCNPPPGLPPPVIFWMSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNARFH 217

Query: 1455 AVNEVDISDA-SETTEYYKVIKETKIQSPTVEKPLKNIT-TEPN---------------- 1496
              + +   +  +   +  K   ET +++ T     + +T T P+                
Sbjct: 218  FTHTIQQKNPYTLKVKTKKPHNETSLRNHTDMYSARGVTETTPSFMYPYGTSSSQMVLRG 277

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555
             D+ L CI  GVP P + WY+ G +L   K   EN                 Y C+A N 
Sbjct: 278  VDLLLECIASGVPAPDIMWYKKGGELPAGKTKLENFNKALRISNVSEEDSGEYFCLASNK 337

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             G +  +  V ++  P      +++      G++  +     G P P + W  NG  +E 
Sbjct: 338  MGSIRHTISVRVKAAPYWLDEPQNLIL--APGEDGRLVCRANGNPKPSIQWLVNGEPIEG 395

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                N + +     I  ++ +   S+ Y   ASN  G       + V D P +   P
Sbjct: 396  SPP-NPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDVPPRILAP 451



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 107/488 (21%), Positives = 181/488 (37%), Gaps = 57/488 (11%)

Query: 1046 DVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
            D++W ++ GE+   K    +F K      L I N S  D GEY C+  ++  +   T+  
Sbjct: 293  DIMWYKKGGELPAGKTKLENFNKA-----LRISNVSEEDSGEYFCLASNKMGSIRHTISV 347

Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKK 1160
             V+  P  +   QN  +  G                ++W  +G  I+ S     + +   
Sbjct: 348  RVKAAPYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPP-NPSREVAG 406

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
              +   D  +  +  Y C   N     +      +    L +P  IL P N      ++ 
Sbjct: 407  DTIVFRDTQIGSSAVYQCNASNEHGYLLAN----AFVSVLDVPPRILAPRN-QLIKVIQY 461

Query: 1221 PDETLD----------VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                LD          + W+K  +  + D   +    +      + RK   +DQ  YTCV
Sbjct: 462  NRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEMSMARK---EDQGIYTCV 518

Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSK 1326
              +     + +V + V+ P +IV    +  +KRGS   L   V +    +    W+ +  
Sbjct: 519  ATNILGKVEAQVRLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLKDDA 578

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-------D 1379
             +      K   D     LTI  V   D G Y             +  +T+L       +
Sbjct: 579  PLYIGNRMKKEDDG----LTIYGVAEKDQGDYTCVASTELDKDSAKAYLTVLALPITPAE 634

Query: 1380 KPSPPGKPNILEIDS---SSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWISVKNIT 1434
            KP  P +P  LE+      S+ + W  P +  NS I  Y+V+++E       W +     
Sbjct: 635  KPERPDRPRDLELSDLAERSVKLTWI-PGDDNNSPITDYIVQFEEDRFQPGTWHNHSRYP 693

Query: 1435 -KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV------IKETKIQSPTVEKP 1487
                +++ +L    +Y+FR  AVN+V  S  S  +E Y+       I  T +Q    +K 
Sbjct: 694  GNVNSALLSLSPYVNYQFRVIAVNDVGSSLPSMPSERYQTSGARPEINPTGVQGAGTQKN 753

Query: 1488 LKNITTEP 1495
               IT  P
Sbjct: 754  NMEITWTP 761



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 29/136 (21%), Positives = 59/136 (43%), Gaps = 5/136 (3%)

Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
           +  +E P +    P +     ++  V  +  I +      NPVP+ +W RN +  + ++ 
Sbjct: 27  ISAIEVPLDLPQPPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKD 86

Query: 879 ITQNFDGENIELVIT-NVDSEID--SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHL 934
              +    +  LVI  +     D   G+Y+C A N  G ++  +++ + V +   + K  
Sbjct: 87  PKVSMRRRSGTLVIDFHGGGRPDDYEGEYQCFARNDYG-TALSSKIHLQVSRSPLWPKEK 145

Query: 935 QKSYETEEGKTVILEC 950
               E +EG  + L+C
Sbjct: 146 VDVIEVDEGAPLSLQC 161



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC   G P P I W+++   + P+   ++  ++ N A L I  V  ED+G + C
Sbjct: 277 GVDLLLECIASGVPAPDIMWYKKGGEL-PAGKTKL--ENFNKA-LRISNVSEEDSGEYFC 332

Query: 584 VAKNAAGFASSTTELIVEA 602
           +A N  G    T  + V+A
Sbjct: 333 LASNKMGSIRHTISVRVKA 351


>UniRef50_Q4STB0 Cluster: Chromosome 11 SCAF14249, whole genome
            shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
            Chromosome 11 SCAF14249, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 673

 Score =  109 bits (262), Expect = 8e-22
 Identities = 80/318 (25%), Positives = 140/318 (44%), Gaps = 17/318 (5%)

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682
            + EK+     K  K + ++ Y  E   T G  S + TL + DKP++P+GPV + E +  S
Sbjct: 86   SSEKSEGRWYKNGKLADAALYHFE---TEGRKS-QATLAIQDKPTQPQGPVDVTESAVTS 141

Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742
            V  +WKPP D GG  ++ Y IE+ +   N+W  V +V     ++    ++   +Y +R+ 
Sbjct: 142  VEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRIR 201

Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802
            A+N  G S+ LE+E I     L  P              + + +TW     NGG+ I+ Y
Sbjct: 202  AKNAEGVSDYLETEDI-SAGVLRYPGPPSAPKVASTF-KDHINLTWSCPCDNGGTKILGY 259

Query: 1803 KVEIKQEGKK-WKXXXX---XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858
             +E K++G   W               ++ +     Y+FR+ A N  GT  P    D + 
Sbjct: 260  NLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPSIPCDTVI 319

Query: 1859 IGKTLTPPSQPRNFVVSES---TSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWT 1913
                L PP   + + +  +      + +L W +P    G       Y +E + V+   W 
Sbjct: 320  ARDPLKPPG--KGYQIESNILWIYTTFSLAWMKPREIKGQEDEAQGYYVEIRPVESLQWI 377

Query: 1914 KIVTVGGSVHEHCIENIK 1931
            +  +V  ++  + +  +K
Sbjct: 378  RCNSVSTTLTSYSVRGLK 395



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 58/191 (30%), Positives = 91/191 (47%), Gaps = 8/191 (4%)

Query: 1866 PSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            P+QP+  V V+ES   SV  KW  P+  GG  ++ Y+IE + V    W+ +  V GS   
Sbjct: 125  PTQPQGPVDVTESAVTSVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPS 184

Query: 1925 HCIENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
                ++    +  +RI A+N  GVS  L TE  S  + ++   P PP+AP        +I
Sbjct: 185  FKDSDVDPGRKYCYRIRAKNAEGVSDYLETEDISAGVLRY---PGPPSAPKVASTFKDHI 241

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRI 2041
             +T W  P  +GG  +LGYN+  +      W  V  +  +    + ++D+ E   Y  R+
Sbjct: 242  NLT-WSCPCDNGGTKILGYNLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRV 300

Query: 2042 YARNEIGLSEP 2052
             A N  G  +P
Sbjct: 301  SAINLSGTGDP 311



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 65/280 (23%), Positives = 113/280 (40%), Gaps = 22/280 (7%)

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
            +  Y A P P   W  +       KH   +   K + L I   E TD+GIY + ++N  G
Sbjct: 397  MASYWASPLPEVTWFKDG--FPMPKHVTITNYDKGSQLLIPTSEWTDSGIYTINVKNIVG 454

Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
                 + V + D P PPG   + +    ++ I W    +      ++Y+V+ ++     W
Sbjct: 455  QESFNIEVKVTDDPKPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTW 514

Query: 1428 ISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK-------- 1478
             +V  N+   + ++ N+     Y FR +A N++ +S  SE +  +++ KE +        
Sbjct: 515  KTVADNLFNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSE-SPVFEIKKEKEKPSINMLK 573

Query: 1479 -----IQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
                 +QS P+   PL+        +  ++C   G P P VTWY +   L T    Y   
Sbjct: 574  KKSLDLQSPPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYITN 633

Query: 1533 X----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
                               YK +  N  G  E+S V+ ++
Sbjct: 634  VCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESSMVMNVR 673



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 55/169 (32%), Positives = 79/169 (46%), Gaps = 4/169 (2%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P PEV W+K+G  +   K   IT  +K S + I   + + S  YTI   N  G  S  + 
Sbjct: 404  PLPEVTWFKDGFPMP--KHVTITNYDKGSQLLIPTSEWTDSGIYTINVKNIVGQESFNIE 461

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719
            +KV D P KP GPV + +    +VTI W    D+   +   Y ++K +     W  VAD 
Sbjct: 462  VKVTDDP-KPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTWKTVAD- 519

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768
            +     + +  +    EY FRV A+N +G S   ES    IK   + PS
Sbjct: 520  NLFNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSESPVFEIKKEKEKPS 568



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 63/263 (23%), Positives = 106/263 (40%), Gaps = 11/263 (4%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINT--TYQFRI 1839
            SV   W P +  GG  +  Y +E +Q G+ KW             +   ++    Y +RI
Sbjct: 141  SVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRI 200

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
             A+N  G S  Y   + I+ G  L  P  P    V+ +    + L W+ P  NGG+ I  
Sbjct: 201  RAKNAEGVS-DYLETEDISAG-VLRYPGPPSAPKVASTFKDHINLTWSCPCDNGGTKILG 258

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
            Y +E K  KG ++  +V   G + +  + ++++ E     FR+SA N  G   P+     
Sbjct: 259  YNLE-KKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPSIPCDT 317

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGAP--LLGYNIAIRDVTKTMWM 2014
             + +    P      +E  ++      + +W  P    G      GY + IR V    W+
Sbjct: 318  VIARDPLKPPGKGYQIESNILWIYTTFSLAWMKPREIKGQEDEAQGYYVEIRPVESLQWI 377

Query: 2015 EVGKVDVNTLKFNIRDLSENHTY 2037
                V      +++R L    +Y
Sbjct: 378  RCNSVSTTLTSYSVRGLKAMASY 400



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI 1399
            KS     K  +  DA +Y    E     A     + I DKP+ P  P ++ E   +S+  
Sbjct: 89   KSEGRWYKNGKLADAALYHFETEGRKSQA----TLAIQDKPTQPQGPVDVTESAVTSVEF 144

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVN 1457
             W  P++ G  T+  YV+E +++   +W +V  +  +  S +  ++     Y +R  A N
Sbjct: 145  KWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRIRAKN 204

Query: 1458 EVDISDASETTE 1469
               +SD  ET +
Sbjct: 205  AEGVSDYLETED 216



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 1358 YKLRLENNCGHADV----EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
            Y++R +N  G +D     +++  +L  P PP  P +       IN+ W  P + G + I+
Sbjct: 198  YRIRAKNAEGVSDYLETEDISAGVLRYPGPPSAPKVASTFKDHINLTWSCPCDNGGTKIL 257

Query: 1414 YYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             Y +E ++  T  W  V     IT T  +++++   ++Y FR  A+N     D S
Sbjct: 258  GYNLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPS 312



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 27/92 (29%), Positives = 43/92 (46%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P+ P  P+++       V   W  P+  GG  +  Y I  R V +  W  VG+V  +   
Sbjct: 125  PTQPQGPVDVTESAVTSVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPS 184

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            F   D+     Y  RI A+N  G+S+ LE+++
Sbjct: 185  FKDSDVDPGRKYCYRIRAKNAEGVSDYLETED 216



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 3/116 (2%)

Query: 710 VVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768
           V  + +E E     +LK K+ + + PP    PL+  +  QG    +S  + G+P P +TW
Sbjct: 557 VFEIKKEKEKPSINMLKKKSLDLQSPPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTW 616

Query: 769 CKNNKPVKALPTKSDGDTHSI-TILKPK-KVKDEGVYTLKAENSEGIAETSAVITV 822
             NN  +         +   + ++L PK   KD G Y +  EN  G AE+S V+ V
Sbjct: 617 YLNNISLNTNTNYYITNVCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESSMVMNV 672



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
           KK  EK   + + +K + + QS  P F   LR    P G      C ++G P P +TW+ 
Sbjct: 561 KKEKEK-PSINMLKKKSLDLQS-PPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYL 618

Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
               +  + ++ +  +   V +L+I +V P+D G +  V +N  G A S+
Sbjct: 619 NNISLNTNTNYYI-TNVCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESS 667



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 7/122 (5%)

Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
            D  I+ I+ +N VG       +S  +E   T    P  P+++       V  SW +   +
Sbjct: 441  DSGIYTINVKNIVG------QESFNIEVKVTDDPKPPGPVKLDQNILGTVTISWLSSPDE 494

Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
                 L Y +  RD  K  W  V     N  KF + ++     Y  R++A+N+IGLS P 
Sbjct: 495  KRDDRLHYLVKKRDSFKRTWKTVADNLFNN-KFTVVNVLPGREYHFRVFAKNDIGLSPPS 553

Query: 2054 ES 2055
            ES
Sbjct: 554  ES 555



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 1/107 (0%)

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920
            K    P  P    + ++   +VT+ W            +Y+++ +    ++W K V    
Sbjct: 463  KVTDDPKPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTW-KTVADNL 521

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
              ++  + N+    E  FR+ A+N +G+S P+ES    ++K    PS
Sbjct: 522  FNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSESPVFEIKKEKEKPS 568



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 20/76 (26%), Positives = 32/76 (42%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E  ++  I+G P P V WY N   L  +  Y IT       + I ++      +Y + 
Sbjct: 597  GYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYITNVCGVCSLLIPKVSPKDGGEYKVV 656

Query: 1647 ASNTAGTSSVEVTLKV 1662
              N  GT+   + + V
Sbjct: 657  VENKLGTAESSMVMNV 672



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 4/96 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP+FS   +     +G +  + C +   P P + W      +  + N  +   +++   C
Sbjct: 582 PPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYI---TNVCGVC 638

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
           S+L I  V     G Y VV  N+ G A   +V+ ++
Sbjct: 639 SLL-IPKVSPKDGGEYKVVVENKLGTAESSMVMNVR 673


>UniRef50_A6H8Q3 Cluster: Zgc:165344 protein; n=9; Clupeocephala|Rep:
            Zgc:165344 protein - Danio rerio (Zebrafish) (Brachydanio
            rerio)
          Length = 529

 Score =  108 bits (260), Expect = 1e-21
 Identities = 76/317 (23%), Positives = 149/317 (47%), Gaps = 22/317 (6%)

Query: 1277 TKLKVEVVEFPP-KIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
            T L  EVV+ P  ++  + R+  +K+ G  + L++ +   PQP   W  + + I   K  
Sbjct: 209  TVLVREVVDRPKIRLPRFLRQRYVKKVGEKINLVIPFGGKPQPVVSWTKDGQPIDTKKVN 268

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
              + D K +   I+  E  D+G+Y++ ++ +      ++ + I++ P PP    I++   
Sbjct: 269  IRNSD-KDSIFFIRAAERVDSGVYEMCVKVDSFEDKAQLTLQIIELPGPPASVKIVDTWG 327

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRA 1453
             ++ + W EP++ GN+TI  Y ++  +  T +W +V ++  +   +I +L   ++Y FR 
Sbjct: 328  FNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNATISDLIMGNTYIFRV 387

Query: 1454 YAVNEVDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIE 1500
            +  N+  IS  + TT+    I++T I             ++P    P+++ +T    + +
Sbjct: 388  FTENKCGISQEATTTKTSATIQKTGIDYKPPVYKEHDFSEAPKFTTPMQDRSTTVGYNTK 447

Query: 1501 LTCIFGGVPQPKVTWYRD----GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            L C   G P+PK+ W ++    G   K  +   +                 Y C A N+H
Sbjct: 448  LLCAVRGFPKPKIEWLKNQMIIGDDPKFRQINNQGICSLEIRKPGNFDGGVYSCRAKNEH 507

Query: 1557 GEVETSCVVGIQQKPVI 1573
            GE   +C + ++Q PVI
Sbjct: 508  GEAVVTCKLEVKQ-PVI 523



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 9/211 (4%)

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            +T  V  +  +P I +    ++Q++  KVG++  +     G P P V W K+G  ++  K
Sbjct: 208  DTVLVREVVDRPKIRLPRF-LRQRYVKKVGEKINLVIPFGGKPQPVVSWTKDGQPIDT-K 265

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
            + NI   +K S+  I+  +R  S  Y +     +     ++TL++ + P  P    I+ +
Sbjct: 266  KVNIRNSDKDSIFFIRAAERVDSGVYEMCVKVDSFEDKAQLTLQIIELPGPPASVKIV-D 324

Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
                +V +EW  P D+G   +T Y I+K +     W  V +    +    I  L     Y
Sbjct: 325  TWGFNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNA-TISDLIMGNTY 383

Query: 1738 MFRVIAQNPVGFSE---ALESEPIVIKTALD 1765
            +FRV  +N  G S+     ++   + KT +D
Sbjct: 384  IFRVFTENKCGISQEATTTKTSATIQKTGID 414



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 44/159 (27%), Positives = 70/159 (44%), Gaps = 10/159 (6%)

Query: 1381 PSPPGKP---NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435
            P P  +P    + +++ +S+ I W  P   GNS +  YVVE  +  T +W +        
Sbjct: 115  PEPTSEPLELGVEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVS 174

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDIS---DASETTEYYKVIKETKIQSPTVEKPLKNIT 1492
             +  I+N  T      R  A+N    S     ++T    +V+   KI+ P   +  +   
Sbjct: 175  CRYVIKNQTTGDRLNIRVVAMNPGGRSPPATLADTVLVREVVDRPKIRLPRFLR--QRYV 232

Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
             +  E I L   FGG PQP V+W +DG+ + T K    N
Sbjct: 233  KKVGEKINLVIPFGGKPQPVVSWTKDGQPIDTKKVNIRN 271



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 10/276 (3%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835
            +++ SV I+W P    G S +  Y VE+ +EG   WK          R  I+  +     
Sbjct: 129  VNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVSCRYVIKNQTTGDRL 188

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
              R+ A N  G S P T  D + + + +  P       + +   + V  K       GG 
Sbjct: 189  NIRVVAMNPGGRSPPATLADTVLVREVVDRPKIRLPRFLRQRYVKKVGEKINLVIPFGGK 248

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            P    ++ +        TK V +  S  +  I  I+  + +   +  E  V V    +  
Sbjct: 249  P--QPVVSWTKDGQPIDTKKVNIRNS-DKDSIFFIRAAERVDSGVY-EMCVKVDSFEDKA 304

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
             + L+    +P PP +   +   G N+ +  W  P+ +G   + GY I   D     W  
Sbjct: 305  QLTLQI-IELPGPPASVKIVDTWGFNVAL-EWTEPKDNGNTTITGYTIQKADKKTGDWFT 362

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            V +   + L   I DL   +TY+ R++  N+ G+S+
Sbjct: 363  VLE-HYHRLNATISDLIMGNTYIFRVFTENKCGISQ 397



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 4/111 (3%)

Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
           K PV+++    + S AP F   ++ + T  G   +  C V G+P+P+I W +   II   
Sbjct: 416 KPPVYKE---HDFSEAPKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKIEWLKNQMIIGDD 472

Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
             F+   ++  + +L IR+    D G ++C AKN  G A  T +L V+ P+
Sbjct: 473 PKFRQ-INNQGICSLEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVKQPV 522



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 3/106 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P +  + ++   +V L+WTEP+ NG + IT Y I+    K   W  ++     ++  
Sbjct: 314  PGPPASVKIVDTWGFNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNA- 372

Query: 1926 CIENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATVPSPP 1969
             I ++   +  IFR+  EN  G+S    T   S  ++K      PP
Sbjct: 373  TISDLIMGNTYIFRVFTENKCGISQEATTTKTSATIQKTGIDYKPP 418



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 3/127 (2%)

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
           T T   + + G    P V K +    E P+   P++      G +  L   V G P+P I
Sbjct: 402 TKTSATIQKTGIDYKPPVYK-EHDFSEAPKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKI 460

Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEE 824
            W KN   +   P     +   I  L+ +K    D GVY+ +A+N  G A  +  + V++
Sbjct: 461 EWLKNQMIIGDDPKFRQINNQGICSLEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVKQ 520

Query: 825 PTEENAE 831
           P   +A+
Sbjct: 521 PVIADAD 527



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNE 1733
            + +++  SVTI W+PP   G   L  Y +E  +     W K A+ +  V   Y I+    
Sbjct: 126  VEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADW-KAANEELTVSCRYVIKNQTT 184

Query: 1734 NCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767
                  RV+A NP G S  A  ++ ++++  +D P
Sbjct: 185  GDRLNIRVVAMNPGGRSPPATLADTVLVREVVDRP 219



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 23/87 (26%), Positives = 34/87 (39%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924
            P S+P    V +    SVT+ W  P + G S +  Y++E        W            
Sbjct: 117  PTSEPLELGVEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVSCR 176

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLP 1951
            + I+N    D +  R+ A N  G S P
Sbjct: 177  YVIKNQTTGDRLNIRVVAMNPGGRSPP 203



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F+   + +    G +  L C +   P+P I WL K + I+ D+     I +     CS
Sbjct: 429 PKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKIEWL-KNQMIIGDDPKFRQINNQG--ICS 485

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
            L+I     F  G Y+  A N  GEA +   L++K
Sbjct: 486 -LEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVK 519


>UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA,
            isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG12002-PA, isoform A - Tribolium castaneum
          Length = 1388

 Score =  107 bits (258), Expect = 3e-21
 Identities = 93/370 (25%), Positives = 162/370 (43%), Gaps = 27/370 (7%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
            P+++E  + + +  G + + + +V G+P+P+I W +++K ++    K D   +   ++K 
Sbjct: 234  PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNGSLVIKH 293

Query: 795  KKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEE----NAEPPLFINRFQEITVKEKGT 849
                D G Y   A+N +G +    A + +  P ++    N  P   +      T +   +
Sbjct: 294  TDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTSESDPS 353

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            + L  +   NP P+ITW RN   ++ S+   ++F  E+  LVI  V +  D G Y+C A+
Sbjct: 354  VSLHCKAFGNPHPTITWSRNGIQLTTSQ---RHFIDEDGTLVIRPVKAS-DHGTYRCDAT 409

Query: 910  NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEI 967
            NS G+ S  A V ++V  V F  H Q + ET  G T+ LEC    S      W+ +  E+
Sbjct: 410  NSNGRISSEADVIVNVAPV-FTVHPQNT-ETTPGSTIKLECFAVGSPPPEITWFKDDLEV 467

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETI---PEFI 1020
                   I  +G             D G+  C  ++    +E S  + V       P+FI
Sbjct: 468  RSDGRLSISPDG--SSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPKFI 525

Query: 1021 RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079
             K  + E        L  + + + T  + W++DG  ++    +    K   I  LYI   
Sbjct: 526  YKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQ----RTGRTKVSLIGNLYIYGV 581

Query: 1080 SVHDEGEYSC 1089
               D+G Y C
Sbjct: 582  VPDDQGRYEC 591



 Score =  106 bits (254), Expect = 8e-21
 Identities = 111/431 (25%), Positives = 166/431 (38%), Gaps = 45/431 (10%)

Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555
           P+    T +    AP  +E  +      GST  F C+V G P+P I W R    I+ + D
Sbjct: 220 PLKGMTTRDFHCKAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNND 279

Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE--LIVEAPLSDHGSEMTV 613
               YD  +  +LVI+     D+G + C+AKN  G   S     ++V       G   + 
Sbjct: 280 ---KYDIMDNGSLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGS- 335

Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS-DILLECRLVAIPEPDIAWLFKGE 672
                               P F   P +    E    + L C+    P P I W   G 
Sbjct: 336 --------------------PVFLVTPVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGI 375

Query: 673 EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
           ++   +     I+ D       L I  VK    GTY   A N  G  S    + +     
Sbjct: 376 QLTTSQRHF--IDED-----GTLVIRPVKASDHGTYRCDATNSNGRISSEADVIVNVA-- 426

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
            P   + P ++     G ++ L    VG+P P ITW K++  V++    S     S   +
Sbjct: 427 -PVFTVHP-QNTETTPGSTIKLECFAVGSPPPEITWFKDDLEVRSDGRLSISPDGSSLQI 484

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
              K  D G+Y  +A N  G  E SA + V   T    +PP FI +   I      TI+L
Sbjct: 485 HNAKETDSGLYICEARNHLGFREVSAKVKV---TPLARKPPKFIYKPYNIEALVGSTIEL 541

Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
             +   +P P I W ++   +  +     +  G    L I  V  + D G Y+C A N  
Sbjct: 542 PCKADGDPTPGIQWQKDGASLQRTGRTKVSLIGN---LYIYGVVPD-DQGRYECAAINDF 597

Query: 913 GKSSHGARVTI 923
           G+S+    VT+
Sbjct: 598 GRSTASCYVTV 608



 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 87/328 (26%), Positives = 137/328 (41%), Gaps = 27/328 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P   + P+   +  GS  +  CR+   P+P I W+   +EI  + +     + D+ M   
Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNND-----KYDI-MDNG 287

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVL-----KIKTGEKEPPQVIEPLKSMI 745
            L I +  +   G Y  +A N +GE  S P  ++L     + + G   P  ++ P+    
Sbjct: 288 SLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTT 347

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
                SV L  +  GNP PTITW +N   +     +   D     +++P K  D G Y  
Sbjct: 348 SESDPSVSLHCKAFGNPHPTITWSRNGIQL-TTSQRHFIDEDGTLVIRPVKASDHGTYRC 406

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            A NS G   + A + V          P+F    Q        TIKL      +P P IT
Sbjct: 407 DATNSNGRISSEADVIVN-------VAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEIT 459

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W++++  +     ++ + DG +++  I N   E DSG Y C A N  G     A+V +  
Sbjct: 460 WFKDDLEVRSDGRLSISPDGSSLQ--IHNA-KETDSGLYICEARNHLGFREVSAKVKVTP 516

Query: 926 EKVTFVKHLQKSYETEE--GKTVILECQ 951
                 K + K Y  E   G T+ L C+
Sbjct: 517 LARKPPKFIYKPYNIEALVGSTIELPCK 544



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 47/184 (25%), Positives = 80/184 (43%), Gaps = 5/184 (2%)

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXXX 1545
            P+   T+E +  + L C   G P P +TW R+G +L T++  + +               
Sbjct: 342  PVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGTLVIRPVKASDH 401

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y+C A N +G + +   V +   PV T+  ++ +     G    +     G PPPE+ 
Sbjct: 402  GTYRCDATNSNGRISSEADVIVNVAPVFTVHPQNTET--TPGSTIKLECFAVGSPPPEIT 459

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W+K+  ++ +D   +I+     S ++I   K + S  Y  EA N  G   V   +KV   
Sbjct: 460  WFKDDLEVRSDGRLSIS--PDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPL 517

Query: 1666 PSKP 1669
              KP
Sbjct: 518  ARKP 521



 Score = 73.3 bits (172), Expect = 7e-11
 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 8/229 (3%)

Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
           T +I     SDHG+                AD++  + P F+  P+      GS I LEC
Sbjct: 390 TLVIRPVKASDHGT-YRCDATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLEC 448

Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
             V  P P+I W     E+  D  +S++ +       S L+I N K+   G Y   A N 
Sbjct: 449 FAVGSPPPEITWFKDDLEVRSDGRLSISPDG------SSLQIHNAKETDSGLYICEARNH 502

Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
            G   +   +K+    ++PP+ I    ++    G ++ L  +  G+P P I W K+   +
Sbjct: 503 LGFREVSAKVKVTPLARKPPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASL 562

Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
           +           ++ I       D+G Y   A N  G +  S  +TV+E
Sbjct: 563 QRTGRTKVSLIGNLYIYGVVP-DDQGRYECAAINDFGRSTASCYVTVKE 610



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 84/397 (21%), Positives = 148/397 (37%), Gaps = 46/397 (11%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            PE +   QD E+     A+    +  +    + W RD + I+   +KYD    G    L 
Sbjct: 234  PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNG---SLV 290

Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF----EIELT 1131
            I++T   D G Y C+ ++E    +  V   P  +I    +Q+   GN +       + +T
Sbjct: 291  IKHTDESDSGHYECMAKNE----DGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVT 346

Query: 1132 KGDA----------------LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
              ++                 + W ++G ++  S    +  DG    L I      D G 
Sbjct: 347  TSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGT---LVIRPVKASDHGT 403

Query: 1176 YSCEVGNSKCTAILTVEEPSIN----FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            Y C+  NS    I +  +  +N    FT+        P +T       +     ++TW+K
Sbjct: 404  YRCDATNSN-GRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFK 462

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE-VVEF 1286
                +    + ++  D    +L I    E D   Y C   +     + + K+KV  +   
Sbjct: 463  DDLEVRSDGRLSISPDGS--SLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARK 520

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PPK +          GS + L       P P  +W  +   +++   TK S+     +L 
Sbjct: 521  PPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQRTGRTKVSL---IGNLY 577

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
            I  V   D G Y+    N+ G +     VT+ +  +P
Sbjct: 578  IYGVVPDDQGRYECAAINDFGRSTASCYVTVKENQNP 614



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 65/298 (21%), Positives = 115/298 (38%), Gaps = 26/298 (8%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PEI+   Q+ +++ G+ A F   +T GD    + W +D  EI+ +N     +D     L 
Sbjct: 234  PEIMEGPQDVEISWGSTAVFTCRVT-GDPKPSIYWMRDDKEIEMNNDKYDIMDNGS--LV 290

Query: 1165 IYDCDLDDAGEYSC-------EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN---TDA 1214
            I   D  D+G Y C       EV +     IL   +         P F++ P +   +++
Sbjct: 291  IKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTSES 350

Query: 1215 YLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              +V +  +        +TW +    +  +++  +  D    TL+IR     D   Y C 
Sbjct: 351  DPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDED---GTLVIRPVKASDHGTYRCD 407

Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
              ++      + +V V   P    + +      GS + L       P P   W  +   +
Sbjct: 408  ATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDDLEV 467

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
            +     + SI    +SL I   + TD+G+Y     N+ G  +V   V +      P K
Sbjct: 468  RS--DGRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPK 523



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 34/398 (8%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P+I++  ++  I  GS           P+P+  W+ + K I+        +D+   SL I
Sbjct: 234  PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDN--GSLVI 291

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-----GKPNILEIDSSSINICWD 1402
            K  + +D+G Y+   +N  G         IL +P        G P  L +   S+     
Sbjct: 292  KHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFL-VTPVSVTTSES 350

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            +P     S  ++         T  W S   I  T +    +  + +   R    ++    
Sbjct: 351  DP-----SVSLHCKAFGNPHPTITW-SRNGIQLTTSQRHFIDEDGTLVIRPVKASDHGTY 404

Query: 1463 DASETTEYYKVIKETKI---QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
                T    ++  E  +    +P      +N  T P   I+L C   G P P++TW++D 
Sbjct: 405  RCDATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDD 464

Query: 1520 KKLKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVIT 1574
             ++++    +   +                Y C A N  G  E S    V  + +KP   
Sbjct: 465  LEVRSDGRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPKF 524

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI---R 1631
            I  +    +  VG    +    +G P P + W K+G  L+       T + K S+I    
Sbjct: 525  I-YKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQR------TGRTKVSLIGNLY 577

Query: 1632 IKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPS 1667
            I  +      +Y   A N  G  T+S  VT+K    P+
Sbjct: 578  IYGVVPDDQGRYECAAINDFGRSTASCYVTVKENQNPT 615



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 14/129 (10%)

Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532
           Y+ +  N+  +  ++++ K+   P+  KP        P F+ K        GST++  C+
Sbjct: 495 YICEARNHLGF--REVSAKVKVTPLARKP--------PKFIYKPYNIEALVGSTIELPCK 544

Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
            +G P P I W +  A ++ +   ++      +  L I  V P+D G + C A N  G +
Sbjct: 545 ADGDPTPGIQWQKDGASLQRTGRTKV----SLIGNLYIYGVVPDDQGRYECAAINDFGRS 600

Query: 593 SSTTELIVE 601
           +++  + V+
Sbjct: 601 TASCYVTVK 609


>UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphatase
            delta precursor; n=183; Eumetazoa|Rep: Receptor-type
            tyrosine-protein phosphatase delta precursor - Homo
            sapiens (Human)
          Length = 1912

 Score =  107 bits (258), Expect = 3e-21
 Identities = 220/1036 (21%), Positives = 393/1036 (37%), Gaps = 111/1036 (10%)

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTID- 1157
            T  E PP       +Q    G  A+F  + T GD   +  W K G ++       +  D 
Sbjct: 18   TDAETPPRFTRTPVDQTGVSGGVASFICQAT-GDPRPKIVWNKKGKKVSNQRFEVIEFDD 76

Query: 1158 GKKQKLKIYDCDLD-DAGEYSCEVGN-----SKCTAILTVEEPSI--NF-TLRL-PEFIL 1207
            G    L+I       D   Y C   N     S  T +  + E  I   F T+ + P+  +
Sbjct: 77   GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136

Query: 1208 VP-ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT---------LIIRK 1257
            V    T   L     +   ++TW+K    ++ +     I  ++  +         L I +
Sbjct: 137  VERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQ 196

Query: 1258 CTEDDQCEYTCVLLDAKST-----TKLKV----EVVEFPPKIVDYEREYRIKRGSDVTLL 1308
              E DQ +Y CV  ++  T       L V    EV   PP+       + I  G  V + 
Sbjct: 197  SEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNIT 256

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368
                  P P  +W++ ++ +       P  D       ++  +   +  Y     +  G 
Sbjct: 257  CVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310

Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTE- 1426
             +    +T+   P PPG P + E  ++SI + WD    +GN   + YY+++++  ++ E 
Sbjct: 311  IEAIAQITVKALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEEL 366

Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--- 1483
            +  +  +  T+ S+  L   S Y FR  AVN +     SE      V+ +T  Q+P+   
Sbjct: 367  YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE-----PVLTQTSEQAPSSAP 421

Query: 1484 --VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXX 1539
              V+  + + TT   +  E     G +   +V +  D  +      K    +        
Sbjct: 422  RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 481

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                     K +AF   G+   S    IQ      +  + +  K +   E   T+++   
Sbjct: 482  LVPQKTYSVKVLAFTSIGDGPLSS--DIQVITQTGVPGQPLNFKAEPESE---TSILLSW 536

Query: 1600 PPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT--AGT 1653
             PP      N   +  D    +E  IT +  TS  R++ LK +    + + A +    G 
Sbjct: 537  TPPRSDTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGLKPNSLYYFRLAARSPQGLGA 595

Query: 1654 SSVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPD-- 1709
            S+ E++ + +  KPS P   +     S  S+ + W+ PP++     +T+Y+I+    D  
Sbjct: 596  STAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGE 655

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
            +++  ++  +  D   Y +++L +  EY   V A   VG     ES  ++I+T  DVPS 
Sbjct: 656  DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPESLSVLIRTNEDVPSG 713

Query: 1770 XXXXXXXXXIDNESVYITW---FPSEKNG---GSPIIDYKVE------------IKQEGK 1811
                     +++ SV ++W    P++++G   G  +   ++E            +     
Sbjct: 714  PPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADA 773

Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
            +W+           I  L   T+Y   + A    G      S  K+ +  T   P +PR 
Sbjct: 774  QWEFDDTTEHDMI-ISGLQPETSYSLTVTAYTTKGDGA--RSKPKL-VSTTGAVPGKPR- 828

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIEN 1929
             V++ +   +  ++W  P    G P+  Y ++F     K    + T+  S  E      +
Sbjct: 829  LVINHTQMNTALIQWHPPVDTFG-PLQGYRLKFGR---KDMEPLTTLEFSEKEDHFTATD 884

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989
            I +    +FR+SA N VG     E     +     VP+     L      S  V  SW  
Sbjct: 885  IHKGASYVFRLSARNKVGFG---EEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQP 941

Query: 1990 PEW-DGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
            P   +    +  Y +  RD+    + ME   V  +T    +  L  + TY +++ A    
Sbjct: 942  PVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADT-TMTLTGLKPDTTYDVKVRAHTSK 1000

Query: 2048 GLSEPLESDEPFKVIP 2063
            G   P      F+ +P
Sbjct: 1001 G-PGPYSPSVQFRTLP 1015



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 81/307 (26%), Positives = 131/307 (42%), Gaps = 26/307 (8%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F++ P  Q    G      C+    P P I W  KG++ V ++   V IE D     
Sbjct: 23  PPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEV-IEFD-DGSG 79

Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748
           SVL+I  ++    E  Y  VA N  GE S+   L +   ++ P   P +    +  +V +
Sbjct: 80  SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139

Query: 749 GESVILSAQVVGNPRPTITWCK---------NNKPVKALPTKSDGDT--HSITILKPKKV 797
             +  +     GNP P ITW K         NN  +K L ++S G T       ++  + 
Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEE 199

Query: 798 KDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
            D+G Y   A NS G   ++ A + V E  E    PP F        +   G++ +    
Sbjct: 200 SDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVA 259

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
             +P+P + W    E ++P + +     G N+ L + +V     S +Y CVA ++ G   
Sbjct: 260 VGSPMPYVKWMLGAEDLTPEDDMP---IGRNV-LELNDVR---QSANYTCVAMSTLGVIE 312

Query: 917 HGARVTI 923
             A++T+
Sbjct: 313 AIAQITV 319



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 19/230 (8%)

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
            +IT+     PP  P   VV+EST+ S+TL W   +S    P++ YII+ K    +   K 
Sbjct: 316  QITVKALPKPPGTP---VVTESTATSITLTW---DSGNPEPVSYYIIQHKPKNSEELYKE 369

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
            +  G +   + +  +    +  FR+ A N +G   P+E    +  + A  PS     ++ 
Sbjct: 370  ID-GVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA--PSSAPRDVQA 426

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTM--WMEVGKVDVNTLKFNIRDLS 2032
            RM+ S  ++  W  PE   G  + GY +    D T+ +  WM+    D       I +L 
Sbjct: 427  RMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQIT--TIGNLV 483

Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKV---IPGEGSHADEEPGEQTEV 2079
               TY +++ A   IG   PL SD        +PG+  +   EP  +T +
Sbjct: 484  PQKTYSVKVLAFTSIG-DGPLSSDIQVITQTGVPGQPLNFKAEPESETSI 532



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 39/311 (12%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV-FPEDAGTFT 582
           G    F CQ  G PRP+I W ++   +   +   + +DD + + L I+ +  P D   + 
Sbjct: 38  GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97

Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
           CVA N  G  S +T L V                           I  G  PT    P+ 
Sbjct: 98  CVASNNVGEISVSTRLTV----------------------LREDQIPRGF-PTIDMGPQL 134

Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC------SVLK 696
           + V+      + C     P+P+I W FK    V   N +  I+               L+
Sbjct: 135 KVVERTRTATMLCAASGNPDPEITW-FKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQ 193

Query: 697 ITNVKKFQEGTYTVVAVNREG-EASLP---IVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           I   ++  +G Y  VA N  G   S P    V +++   + PP+   P  +  +  G SV
Sbjct: 194 IEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSV 253

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            ++   VG+P P + W    + +    T  D       +L+   V+    YT  A ++ G
Sbjct: 254 NITCVAVGSPMPYVKWMLGAEDL----TPEDDMPIGRNVLELNDVRQSANYTCVAMSTLG 309

Query: 813 IAETSAVITVE 823
           + E  A ITV+
Sbjct: 310 VIEAIAQITVK 320



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 92/435 (21%), Positives = 153/435 (35%), Gaps = 54/435 (12%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQD---FQMYYDDDNVAT-----LVIREVFPED 577
           T    C   G P P+ITWF+    +  S +    +    +    T     L I +    D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201

Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637
            G + CVA N+AG   S       AP + +  E+                 +  +PP FS
Sbjct: 202 QGKYECVATNSAGTRYS-------APANLYVRELRE---------------VRRVPPRFS 239

Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
             P    +  G  + + C  V  P P + W+   E++ P        E DM +  +VL++
Sbjct: 240 IPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIGRNVLEL 291

Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILS 755
            +V+  Q   YT VA++  G       + +K   K P  P V E   + I    +S    
Sbjct: 292 NDVR--QSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDS---- 345

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
               GNP P   +   +KP  +     + D  + T      +     Y  +      I  
Sbjct: 346 ----GNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGR 401

Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
                 V   T E A  P    R  +  +    TI +  +    P   I  YR    + P
Sbjct: 402 GPPSEPVLTQTSEQA--PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDP 459

Query: 876 SETITQNFDGENIELVITNVDSEIDSGDY--KCVASNSAGKSSHGARVTIDVEKVTFVKH 933
           ++ +         +  IT + + +    Y  K +A  S G     + + +  +     + 
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519

Query: 934 LQKSYETEEGKTVIL 948
           L    E E   +++L
Sbjct: 520 LNFKAEPESETSILL 534



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 65/275 (23%), Positives = 107/275 (38%), Gaps = 22/275 (8%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP-VIMREISRESVTIEWKPP 1690
            I  L+   S   T+ A  T G  +      V    + P  P +++      +  I+W PP
Sbjct: 787  ISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPP 846

Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
            +D  G  L  Y ++    D    +   +     + +    +++   Y+FR+ A+N VGF 
Sbjct: 847  VDTFG-PLQGYRLKFGRKDMEP-LTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGSPIIDYKV--- 1804
            E +  E   I    +VP+            + SV ++W P   +E+NG   I  Y +   
Sbjct: 905  EEMVKE---ISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNG--IITKYTLLYR 959

Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864
            +I       +           +  L  +TTY  ++ A    G   PY+   +    +TL 
Sbjct: 960  DINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPG-PYSPSVQF---RTL- 1014

Query: 1865 PPSQ--PRNFVVSESTSRSVTLKWTEPES-NGGSP 1896
            P  Q   +NF V      SV L W  PE+ N   P
Sbjct: 1015 PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP 1049


>UniRef50_O94779 Cluster: Contactin-5 precursor; n=52;
            Euteleostomi|Rep: Contactin-5 precursor - Homo sapiens
            (Human)
          Length = 1100

 Score =  107 bits (257), Expect = 3e-21
 Identities = 182/880 (20%), Positives = 341/880 (38%), Gaps = 72/880 (8%)

Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI---LTVEE 1193
            RW ++G+EI   +  + + IDG    +     +  D+G Y C   N+  + +    T++ 
Sbjct: 134  RWLRNGTEIDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLATNTVGSILSREATLQF 191

Query: 1194 PSI-NFTLRLPEFILVPANTDAYLTVEIPDETLDV--TWYKKKS---VIEDTEKFTLISD 1247
              + NF+ R    + V       L    P  + ++  +W   +    V ED+ +F  IS 
Sbjct: 192  AYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRF--ISQ 249

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK---------LKVEVV--EFPPKI-VDYER 1295
             +   L I K    D   Y C++ +  +  +         L+ + V  E+ PKI V +  
Sbjct: 250  -ETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPF 308

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354
                 +G+ V +       P P   W+ VN  I  K +  K       A L I  V+  D
Sbjct: 309  TVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK-----SQAVLEIPNVQLDD 363

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            AGIY+ R EN+ G       + +   P    K N  ++DS S  + W E + TG     Y
Sbjct: 364  AGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGS-PLRW-ECKATGKPRPTY 421

Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
              ++   +  +    V+ +      I N+  + +  ++  A N+     AS      K++
Sbjct: 422  RWLK-NGVPLSPQSRVEMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAE---LKIL 476

Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRX 1533
                  +  + +  K I    ++++ + C   G P+P ++W +  + ++  K        
Sbjct: 477  --ASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDG 534

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y C   N  G  E    + +++   I ++ +  + +  VG+  ++ 
Sbjct: 535  SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPK--RTELTVGESIVLN 592

Query: 1594 --AVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
              A+ +        W   G  ++ ++E     +I  +  ++ + I+ +   H+ +Y    
Sbjct: 593  CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 652

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
              TA + S E  L V   P  P G VI+ EI+  + T+ W P  D+    ++ Y ++   
Sbjct: 653  QTTADSVSDEAELLVRGPPG-PPGIVIVEEITESTATLSWSPAADNHS-PISSYNLQARS 710

Query: 1708 PDNNRWIKVADVDR----DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            P +  W  V  V      D+E+     LN   EY FRV+A NP+G  +   +   +I+T 
Sbjct: 711  PFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDP-STPSRMIRTN 769

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXX 1821
              VP                + I W P SE+        Y V  +  G + WK       
Sbjct: 770  EAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSS 829

Query: 1822 XXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877
              +    R + +   T ++ ++   N  G   P+ S   +       P + P +   +  
Sbjct: 830  EASKFIYRDESVPPLTPFEVKVGVYNNKGDG-PF-SQIVVICSAEGEPSAAPTDVKATSV 887

Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
            +   + + W   + + G P    +  +K ++ +   + V   G+     +  ++      
Sbjct: 888  SVSEILVAWKHIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYH 947

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPT-APLEIR 1976
            F + A N  G   P+   S   +K     SPP+ AP  +R
Sbjct: 948  FTVRAYNGAGYGPPSSEVSATTKK-----SPPSQAPSNLR 982



 Score =  104 bits (249), Expect = 3e-20
 Identities = 198/916 (21%), Positives = 352/916 (38%), Gaps = 77/916 (8%)

Query: 833  PLFINRFQEI---TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI 888
            P+F+    +I   T  ++  + L   V  NPVPS  W RN  EI   S+      DG   
Sbjct: 99   PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT-- 156

Query: 889  ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVI 947
              +I+N     DSG Y+C+A+N+ G S      T+    +  F    + +    EG+ V+
Sbjct: 157  -FIISNPSEAKDSGHYQCLATNTVG-SILSREATLQFAYLGNFSGRTRSAVSVREGQGVV 214

Query: 948  LECQT---SHTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
            L C     S  +   W  N+       D R  I +              DVG   C+VK+
Sbjct: 215  LMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKN 273

Query: 1004 QETSTMLVVKETIPEFIRK---LQDFEVK-EKDVAILEVEINSETADVVWERDGE----I 1055
              T+  ++   T P  +R    + ++E K E             T  +     G     I
Sbjct: 274  TVTNARVLSPPT-PLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTI 332

Query: 1056 IKPKKNKYDFEKRGHIRK----LYIRNTSVHDEGEYSCIL---RDESCTAEVTVVELPPE 1108
               K N Y    +  +RK    L I N  + D G Y C     R ++       V   P 
Sbjct: 333  TWMKVNGY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPH 391

Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167
             + +L + +++ G+   +E + T K     RW K+G  +   + +++ ++G    L I++
Sbjct: 392  WVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-VNG---VLMIHN 447

Query: 1168 CDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIPD 1222
             +  DAG Y C    + G    +A L +   +  F L +L + I+V  + +  +  +   
Sbjct: 448  VNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQG 507

Query: 1223 ETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281
                 ++W K    + + ++  ++ D   R L     ++ D+ +Y C   +   + ++  
Sbjct: 508  SPKPTISWKKGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIA 564

Query: 1282 EV-VEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKII---KKCKHTK 1335
             + V+ P +I    +   +  G  + L     + A       W +  + I   ++  H +
Sbjct: 565  SLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFE 624

Query: 1336 P-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394
                 + SA L I+ +    AG Y  R++        E  + +   P PPG   + EI  
Sbjct: 625  SIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITE 684

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKTQTSIQNLKTNS--S 1448
            S+  + W  P    +S I  Y ++ +   +  W +VK     IT    S   +  N    
Sbjct: 685  STATLSW-SPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVE 743

Query: 1449 YRFRAYAVNEVDISDAS------ETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIEL 1501
            Y FR  A N +   D S       T E       T +   +  +    I  EP +E+ + 
Sbjct: 744  YEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQN 803

Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
               FG +   +    R G K K   ++  ++                K   +N+ G+   
Sbjct: 804  GEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPF 862

Query: 1562 SCVVGI-QQKPVITISNEDIKQKHKVGDEWLVT--AVIEGIPPP---EVIWYKNGNKLEN 1615
            S +V I   +   + +  D+K       E LV    + E +  P   EV ++K+    + 
Sbjct: 863  SQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVGYWKDME--QE 920

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP-EGPVI 1674
            D    + T+   S + +  L+ +    +T+ A N AG       +    K S P + P  
Sbjct: 921  DTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSN 980

Query: 1675 MR-EISRESVTIEWKP 1689
            +R E     V++ W+P
Sbjct: 981  LRWEQQGSQVSLGWEP 996



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 69/235 (29%), Positives = 107/235 (45%), Gaps = 19/235 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P + +K     +D GS +  EC+    P P   WL  G  + P        +S + M   
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSP--------QSRVEMVNG 441

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESV 752
           VL I NV +   G Y  +A N+ G       LKI      P   +  LK ++IV + + V
Sbjct: 442 VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA--PTFALNQLKKTIIVTKDQEV 499

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
           ++  +  G+P+PTI+W K ++ V+     +     S+ IL   K  DEG Y  + EN  G
Sbjct: 500 VIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASK-SDEGKYVCRGENVFG 558

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
            AE  A ++V+EPT     P     +  E+TV E  +I L  +   +    +T+Y
Sbjct: 559 SAEIIASLSVKEPTRIELTP-----KRTELTVGE--SIVLNCKAIHDASLDVTFY 606



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 110/464 (23%), Positives = 184/464 (39%), Gaps = 39/464 (8%)

Query: 645  VDEGSDILLECRLVA-IPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKK 702
            V EG  ++L C      PE   +W+F      V +++     +   ++Y S ++ ++V  
Sbjct: 207  VREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS 266

Query: 703  FQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
            +       V   R      P+ L+     GE EP   +    ++   +G +V +    +G
Sbjct: 267  YICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALG 326

Query: 761  NPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            NP PTITW K N   P KA   KS     ++  +   ++ D G+Y  +AENS G      
Sbjct: 327  NPVPTITWMKVNGYIPSKARLRKS----QAVLEIPNVQLDDAGIYECRAENSRGKNSFRG 382

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             + V          P ++ +  +  +     ++   + T  P P+  W +N   +SP   
Sbjct: 383  QLQV-------YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR 435

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF-VKHLQKS 937
            +    +  N  L+I NV ++ D+G Y+C+A N  G     A + I     TF +  L+K+
Sbjct: 436  V----EMVNGVLMIHNV-NQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKT 490

Query: 938  YETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995
                + + V++EC  Q S   +  W    + +       I+ +G             D G
Sbjct: 491  IIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547

Query: 996  VIKC----IVKDQETSTMLVVKE-TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-- 1048
               C    +    E    L VKE T  E   K  +  V E  V   +  I+  + DV   
Sbjct: 548  KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKA-IHDASLDVTFY 606

Query: 1049 WERDGEIIKPKKNKYDFEK---RGHIRKLYIRNTSVHDEGEYSC 1089
            W   G+ I  ++    FE    +     L IRN  +   G Y C
Sbjct: 607  WTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGC 650



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 113/529 (21%), Positives = 201/529 (37%), Gaps = 55/529 (10%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSIT 790
            +EP  +I P  S      + V L+ +V GNP P+  W +N   +      +      +  
Sbjct: 103  QEPDDIIFPTDS----DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE-ITVKE-KG 848
            I  P + KD G Y   A N+ G       I   E T + A    F  R +  ++V+E +G
Sbjct: 159  ISNPSEAKDSGHYQCLATNTVG------SILSREATLQFAYLGNFSGRTRSAVSVREGQG 212

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
             + + +    +P    +W  N      +E   +    E   L I+ V +  D G Y C+ 
Sbjct: 213  VVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTS-DVGSYICLV 271

Query: 909  SNSAGKS---SHGARVTIDVEKV------TFVKHLQKSYETEEGKTVILEC-QTSHTVST 958
             N+   +   S    +T+  + V          H   +    +G TV +EC    + V T
Sbjct: 272  KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331

Query: 959  -KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKE 1014
              W     +++G    +                  D G+ +C  ++          +   
Sbjct: 332  ITW----MKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVY 387

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRK 1073
            T P ++ KL D ++        E +   +      W ++G  + P+      E    +  
Sbjct: 388  TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR---VEMVNGV-- 442

Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEI-ITRLQNQ-KVNKGNKATFE 1127
            L I N +  D G Y C+  ++      +AE+ ++   P   + +L+    V K  +   E
Sbjct: 443  LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 502

Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGN 1182
             +        + W K    ++ +  I +  DG    L+I +    D G+Y C      G+
Sbjct: 503  CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 559

Query: 1183 SKCTAILTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230
            ++  A L+V+EP+ I  T +  E  L    +       I D +LDVT+Y
Sbjct: 560  AEIIASLSVKEPTRIELTPKRTE--LTVGESIVLNCKAIHDASLDVTFY 606



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 7/96 (7%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P +VEKL       GS +++EC+  G PRP   W +    + P    +M         L+
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN-----GVLM 444

Query: 570 IREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAP 603
           I  V   DAG + C+A+N  G  +AS+  +++  AP
Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP 480



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+TV+ EC   G P P ITW +    I      +      + A L I  V  +DAG + C
Sbjct: 315 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLR-----KSQAVLEIPNVQLDDAGIYEC 369

Query: 584 VAKNAAGFASSTTELIV 600
            A+N+ G  S   +L V
Sbjct: 370 RAENSRGKNSFRGQLQV 386


>UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|Rep:
            CG13521-PB, isoform B - Drosophila melanogaster (Fruit
            fly)
          Length = 1429

 Score =  107 bits (256), Expect = 4e-21
 Identities = 132/539 (24%), Positives = 222/539 (41%), Gaps = 51/539 (9%)

Query: 730  GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS------D 783
            G+ + P++IE    ++V++ E   L+ +V G P PTI W K+ +PV     KS      D
Sbjct: 85   GQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKD 144

Query: 784  GDTHSITILKPKKVKDEGVYTLKAENSEGIAETS-AVITVEEPTEE-NAEPPLFINRFQE 841
            G       ++ KK +D G Y   A+N  G A +  A + +    ++   EP        E
Sbjct: 145  GALFFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGE 204

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-------QNFDGENIELVITN 894
              + E G  K +      P P++ W ++   +   + ++       +  DG N  L+I+N
Sbjct: 205  TALLECGPPKGI------PEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGN--LLISN 256

Query: 895  VDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953
            V+  ID G+YKC+A N  G + S  A++ + V K  F+K   K      G+T    C   
Sbjct: 257  VEP-IDEGNYKCIAQNLVGTRESSYAKLIVQV-KPYFMKE-PKDQVMLYGQTATFHCSVG 313

Query: 954  HTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM 1009
                 K    K+E +  +    I+ + +            D G   C   +   Q ++  
Sbjct: 314  GDPPPKVLWKKEEGNIPVSRARILHDEK--SLEISNITPTDEGTYVCEAHNNVGQISARA 371

Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSETADVVWERDG-EIIKPKKNKYDFEK 1067
             ++    P F ++  + +V    V  L  +   +    V W ++G   +    + +  + 
Sbjct: 372  SLIVHAPPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQH 431

Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEV-----TVVELPPEII-TRLQNQKVN 1119
                  L I +    DEG Y C      +S T  V     ++ E PP II     NQ + 
Sbjct: 432  VAADGTLQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLP 491

Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            KG+ AT     T   +  ++WF DG  +Q  N   + I G    L++ D  L D+G Y+C
Sbjct: 492  KGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYSI-IQG--SSLRVDDLQLSDSGTYTC 548

Query: 1179 ----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
                E G +   A LTVE+P      R  +    PA       + +   ++ + W K +
Sbjct: 549  TASGERGETSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQ 607



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 87/368 (23%), Positives = 143/368 (38%), Gaps = 26/368 (7%)

Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665
           D G+   +            A ++  + P F K+PK Q +  G      C +   P P +
Sbjct: 261 DEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKV 320

Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            W  K EE     NI V+    +H   S L+I+N+    EGTY   A N  G+ S    L
Sbjct: 321 LW--KKEE----GNIPVSRARILHDEKS-LEISNITPTDEGTYVCEAHNNVGQISARASL 373

Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785
            +      PP   +   +  V     V L     GNP P++ W K        P  S G 
Sbjct: 374 IVHA----PPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGR 429

Query: 786 TH----SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
            H        +   + +DEG Y   A +   + ++S V    + +  +  PP  I     
Sbjct: 430 QHVAADGTLQITDVRQEDEGYYVCSAFS---VVDSSTVRVFLQVSSLDERPPPIIQIGPA 486

Query: 842 ITVKEKGTI-KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
                KG++  L  R T NP P I W+ +   +      +    G ++ +    +    D
Sbjct: 487 NQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYS-IIQGSSLRVDDLQLS---D 542

Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL--QKSYETEEGKTVILECQTSHTVST 958
           SG Y C AS   G++S  A +T++    T +       +Y    G   +L    + ++S 
Sbjct: 543 SGTYTCTASGERGETSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPKVLNVSRT-SISL 601

Query: 959 KWYHNKKE 966
           +W  ++++
Sbjct: 602 RWAKSQEK 609



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 115/494 (23%), Positives = 189/494 (38%), Gaps = 62/494 (12%)

Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560
           P    Q  +P  +E                C+VEG P P I WF+    +  ++      
Sbjct: 81  PAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRV 140

Query: 561 DDDNVATLVIREV---FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617
              + A    R +     +D G + CVAKN  G A S    +  A L D   +  V    
Sbjct: 141 QFKDGALFFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRD---DFRVEPKD 197

Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677
                   A +LE  PP    +P   ++ +G           +P  D+    K       
Sbjct: 198 TRVAKGETA-LLECGPPKGIPEPTLIWIKDG-----------VPLDDL----KAMSFGAS 241

Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EAS-LPIVLKIKTGEKEP 734
             + +    +       L I+NV+   EG Y  +A N  G  E+S   +++++K      
Sbjct: 242 SRVRIVDGGN-------LLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVK------ 288

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITIL 792
           P  ++  K  ++  G++      V G+P P + W K   N PV       D  +  I+ +
Sbjct: 289 PYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPVSRARILHDEKSLEISNI 348

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
            P    DEG Y  +A N+ G     A + V         PP F  R     V   G ++L
Sbjct: 349 TP---TDEGTYVCEAHNNVGQISARASLIVH-------APPNFTKRPSNKKVGLNGVVQL 398

Query: 853 VARVTRNPVPSITWYRN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
               + NP PS+ W +   + ++ P+ +  +     +  L IT+V  E D G Y C A +
Sbjct: 399 PCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQE-DEGYYVCSAFS 457

Query: 911 SAGKSSHGARVTIDV----EKVTFVKHLQKSYET-EEGKTVILECQTSHTVS--TKWYHN 963
               S+   RV + V    E+   +  +  + +T  +G    L C+ +   S   KW+H+
Sbjct: 458 VVDSST--VRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHD 515

Query: 964 KKEISGMDHREIIQ 977
              +   +   IIQ
Sbjct: 516 GHAVQAGNRYSIIQ 529



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 151/817 (18%), Positives = 292/817 (35%), Gaps = 78/817 (9%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-- 1345
            P+I+++  +  +K+    TL    +  P+P  EW  + + +   +     +  K  +L  
Sbjct: 90   PRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFF 149

Query: 1346 --TIKKVENTDAGIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
              T++  +  D G Y    +N  G     HA +++ V   D    P    + + +++ + 
Sbjct: 150  YRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLE 209

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS------VKNITKTQTSIQNLKTNSSYRFR 1452
             C   P+     T+I ++ +   +D  + +S      V+ +      I N++      ++
Sbjct: 210  -C-GPPKGIPEPTLI-WIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYK 266

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A N V   ++S    Y K+I + K   P   K  K+      +     C  GG P PK
Sbjct: 267  CIAQNLVGTRESS----YAKLIVQVK---PYFMKEPKDQVMLYGQTATFHCSVGGDPPPK 319

Query: 1513 VTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
            V W ++   +  ++A    +                Y C A N+ G++     + +   P
Sbjct: 320  VLWKKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPP 379

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG--NKLENDKEYNITTKEKTSV 1629
              T       +K  +     +  +  G PPP V W K G    +  +  +          
Sbjct: 380  NFT--KRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGT 437

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV---TIE 1686
            ++I ++++     Y   A +   +S+V V L+V     +P  P+I    + +++   ++ 
Sbjct: 438  LQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPP-PIIQIGPANQTLPKGSVA 496

Query: 1687 WKPPLDDGG-LELTKYAIEKHEPD-NNRW-------IKVADVD-RDVETYCIQKLNENCE 1736
              P    G      K+  + H     NR+       ++V D+   D  TY      E  E
Sbjct: 497  TLPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGE 556

Query: 1737 --YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
              +   +  + P   S    ++P         P           +   S+ + W  S++ 
Sbjct: 557  TSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPK-------VLNVSRTSISLRWAKSQEK 609

Query: 1795 GGS--PIIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL 1849
             G+  PII Y VE      +  W             I  L+  T+Y F + A N  G S+
Sbjct: 610  PGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISV 669

Query: 1850 P---------------YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            P                 S + ++  +TL           S   + +V L+W    S   
Sbjct: 670  PSGLSNTIKTIEADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADE 729

Query: 1895 SPITNYIIEFK--TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
              +    I +K  +V    +  I  +  S     + N+K+  +  F ++         P+
Sbjct: 730  KYVEGLRIHYKDASVPSAQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPS 789

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW-GTPEWDGGAPLLGYNIAIRDVTKT 2011
             S++     +  VPS P   ++I M         W   P       L GY I +      
Sbjct: 790  NSKTAL--TYEDVPSAPPDNIQIGMYNQTAGWVRWTPPPSQHHNGNLYGYKIEVSAGNTM 847

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
              +    ++  T    + +L+    Y +R+ +  + G
Sbjct: 848  KVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAG 884



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 93/490 (18%), Positives = 173/490 (35%), Gaps = 39/490 (7%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P II    +  V K   AT   ++  K +  + WFKDG  +  +      +  K   L  
Sbjct: 90   PRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFF 149

Query: 1166 YDC----DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT------DAY 1215
            Y         D GEY C   N    A+      S+   +   +F + P +T       A 
Sbjct: 150  YRTMQGKKEQDGGEYWCVAKNRVGQAV--SRHASLQIAVLRDDFRVEPKDTRVAKGETAL 207

Query: 1216 LTV----EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEY 1266
            L       IP+ TL   W K    ++D +  +  +  + R      L+I      D+  Y
Sbjct: 208  LECGPPKGIPEPTL--IWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNY 265

Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             C+   L+  + ++  K+ +V+  P  +   ++  +  G   T        P P   W  
Sbjct: 266  KCIAQNLVGTRESSYAKL-IVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLW-- 322

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
              K       ++  I     SL I  +  TD G Y     NN G      ++ +   P+ 
Sbjct: 323  -KKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNF 381

Query: 1384 PGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
              +P+  ++    +N     P   +GN     +  + + + T  + +  +  +   +   
Sbjct: 382  TKRPSNKKV---GLNGVVQLPCMASGNPPPSVFWTK-EGVSTLMFPNSSHGRQHVAADGT 437

Query: 1443 LK-TNSSYRFRAYAV-NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            L+ T+       Y V +   + D+S    + +V    +   P ++    N T        
Sbjct: 438  LQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVAT 497

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
            L C   G P P++ W+ DG  ++   + +                   Y C A  + GE 
Sbjct: 498  LPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGET 557

Query: 1560 ETSCVVGIQQ 1569
              +  + +++
Sbjct: 558  SWAATLTVEK 567



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 4/107 (3%)

Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
           VF + +S ++   PI       +  P GS     C+  G P P+I WF     ++    +
Sbjct: 466 VFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRY 525

Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +       ++L + ++   D+GT+TC A    G  S    L VE P
Sbjct: 526 SIIQG----SSLRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKP 568



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 29/209 (13%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXX 1538
            QSP + +   ++  + NE   L C   G P+P + W++DG+ + T  K ++  +      
Sbjct: 88   QSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGAL 147

Query: 1539 XXXXX-------XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C+A N  G+   S    +Q    I +  +D + + K  D  +
Sbjct: 148  FFYRTMQGKKEQDGGEYWCVAKNRVGQA-VSRHASLQ----IAVLRDDFRVEPK--DTRV 200

Query: 1592 V---TAVIE-----GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI-----RIKELKRS 1638
                TA++E     GIP P +IW K+G  L++ K  +     +  ++      I  ++  
Sbjct: 201  AKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPI 260

Query: 1639 HSSKYTIEASNTAGT-SSVEVTLKVYDKP 1666
                Y   A N  GT  S    L V  KP
Sbjct: 261  DEGNYKCIAQNLVGTRESSYAKLIVQVKP 289


>UniRef50_Q4RFP3 Cluster: Chromosome 16 SCAF15113, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
            SCAF15113, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1184

 Score =  106 bits (255), Expect = 6e-21
 Identities = 90/341 (26%), Positives = 143/341 (41%), Gaps = 18/341 (5%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMREISRESVTIEWK 1688
            I+ L RS   K+ + A N+ G S+    +++    D+PS P  PVI   +   S  + W+
Sbjct: 511  IRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKPVIRGRVLPTSFKMAWE 570

Query: 1689 PPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            PP DDGG E+TKY +E  E      W  V       + +  + L   C Y  RV   +  
Sbjct: 571  PPKDDGGAEITKYVVELSEGLSGVSWELV--YSGPAKEHVCEGLKPGCSYQTRVYCMSEG 628

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI- 1806
            G S    SE + ++T    P                V + W P + +GGSP+  Y VE+ 
Sbjct: 629  GQSPL--SETLQVQTPAVPPGTCLAPRLAGKPKAREVQLRWGPPQVDGGSPVSCYSVEMC 686

Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866
             Q+ ++ +           +  L    TY FRI A N+ G   P++   ++T G     P
Sbjct: 687  GQQSEESREVYQGPELDCSVGGLMPGKTYSFRIKAANKAGFG-PFSERCEVTTGP--GAP 743

Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
             Q +   +   +   V + W  P  N G+P+T Y +E+   +G       T     HE  
Sbjct: 744  EQCKAPSIMCKSPTCVVISWEAPPCN-GAPVTEYRLEWGAAEG-CMQMCYTGPALCHE-- 799

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967
            ++ +        R  A N  GV     S++V  +   +VP+
Sbjct: 800  MKGLSPATNYFCRTQAVNVAGVG--PFSEAVLCQTPCSVPA 838



 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 100/405 (24%), Positives = 168/405 (41%), Gaps = 26/405 (6%)

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G  S  V+         P  P      ++ S+ ++WK P D+G  ++  Y ++  E    
Sbjct: 340  GNPSEPVSFTTLSCEPDPPNPPRKASGTKNSLVLQWKAPCDNGS-KIQNYILQWDEGKGT 398

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
               +        + Y + KL+    Y FR+ A+N +G SE   SE + + T+  VP    
Sbjct: 399  GIYEQCYYGPQKQ-YRVTKLSPASRYAFRLAAKNDMGVSEF--SEVVDLFTSCSVPLPPF 455

Query: 1772 XXXXXXXIDNESVYITWF--PSEKNGGSPIID---YKVEIKQEGKKW--KXXXXXXXXXA 1824
                    + E   +TW     ++   SP  D   Y +E+++EG  +  +          
Sbjct: 456  PP------ELEKAGVTWLCLKWQRPTSSPKEDDIYYILEMEEEGSGYGFQPSYDGEELTC 509

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
             I+ L+ +T Y+FR+ A N  G S P    + IT     + P +P   +       S  +
Sbjct: 510  TIRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKP--VIRGRVLPTSFKM 567

Query: 1885 KWTEPESNGGSPITNYIIEFKT-VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
             W  P+ +GG+ IT Y++E    + G SW  + +  G   EH  E +K       R+   
Sbjct: 568  AWEPPKDDGGAEITKYVVELSEGLSGVSWELVYS--GPAKEHVCEGLKPGCSYQTRVYCM 625

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            +  G S P  S++++++  A  P    AP       +  V   WG P+ DGG+P+  Y++
Sbjct: 626  SEGGQS-PL-SETLQVQTPAVPPGTCLAPRLAGKPKAREVQLRWGPPQVDGGSPVSCYSV 683

Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             +         EV       L  ++  L    TY  RI A N+ G
Sbjct: 684  EMCGQQSEESREV--YQGPELDCSVGGLMPGKTYSFRIKAANKAG 726



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 38/140 (27%), Positives = 68/140 (48%), Gaps = 5/140 (3%)

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNIL- 1390
            +PS D +  + TI+ +  +    +++   N+ G ++    V ++   D+PS P KP I  
Sbjct: 499  QPSYDGEELTCTIRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKPVIRG 558

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSY 1449
             +  +S  + W+ P++ G + I  YVVE  E +    W  V +    +   + LK   SY
Sbjct: 559  RVLPTSFKMAWEPPKDDGGAEITKYVVELSEGLSGVSWELVYSGPAKEHVCEGLKPGCSY 618

Query: 1450 RFRAYAVNEVDISDASETTE 1469
            + R Y ++E   S  SET +
Sbjct: 619  QTRVYCMSEGGQSPLSETLQ 638



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 67/263 (25%), Positives = 105/263 (39%), Gaps = 22/263 (8%)

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845
            I W P   N GS I  Y +++   G++             IQ L  +T+Y+ RI A N +
Sbjct: 885  ICWDPP-CNHGSEITSYSIDL---GERQPIVIGPVTKHI-IQHLQPDTSYRIRIQALNSL 939

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEF 1904
            G   P++   K+   KT   P QP     +  + +++ LKW + P     S    Y ++ 
Sbjct: 940  GAG-PFSHTFKL---KTKPLPPQPPRLECTAFSHQTLRLKWGDGPAKASTSDALQYQLQM 995

Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
            +   G+    I    G  H H ++ + E     FRI A N  G     E     +    T
Sbjct: 996  EDKSGRF---ISLYKGPCHTHKVQRLNESTSYTFRIQAFNEAG-----EGPFSTVYTFTT 1047

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT- 2023
              SPP AP++   V  +   +   T  W+  AP+ G  +       T   E  ++     
Sbjct: 1048 PRSPP-APVKAPKVERHDDNSCEVT--WEALAPMRGDPVIYTLQCMTGNSEFKQLYKGPG 1104

Query: 2024 LKFNIRDLSENHTYMIRIYARNE 2046
              F+I+ L  N  Y  R+ A  E
Sbjct: 1105 TSFHIQSLQLNSDYRFRVCAVRE 1127



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 55/257 (21%), Positives = 106/257 (41%), Gaps = 20/257 (7%)

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W PP + G  E+T Y+I+  E    + I +  V + +    IQ L  +  Y  R+ A N 
Sbjct: 887  WDPPCNHGS-EITSYSIDLGE---RQPIVIGPVTKHI----IQHLQPDTSYRIRIQALNS 938

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVE 1805
            +G      +  +  K     P             ++++ + W     K   S  + Y+++
Sbjct: 939  LGAGPFSHTFKLKTKPLPPQPPRLECTA----FSHQTLRLKWGDGPAKASTSDALQYQLQ 994

Query: 1806 IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            ++ +  ++           ++Q+L+ +T+Y FRI A NE G   P+++    T  +  +P
Sbjct: 995  MEDKSGRFISLYKGPCHTHKVQRLNESTSYTFRIQAFNEAGEG-PFSTVYTFTTPR--SP 1051

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P+  +   V      S  + W       G P+   I   + + G S  K +  G     H
Sbjct: 1052 PAPVKAPKVERHDDNSCEVTWEALAPMRGDPV---IYTLQCMTGNSEFKQLYKGPGTSFH 1108

Query: 1926 CIENIKEKDEIIFRISA 1942
             I++++   +  FR+ A
Sbjct: 1109 -IQSLQLNSDYRFRVCA 1124



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 4/127 (3%)

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN-IC--WDE 1403
            + K+       ++L  +N+ G ++    V +    S P  P   E++ + +  +C  W  
Sbjct: 414  VTKLSPASRYAFRLAAKNDMGVSEFSEVVDLFTSCSVPLPPFPPELEKAGVTWLCLKWQR 473

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDIS 1462
            P ++     IYY++E +E  +          +  T +I+NL  ++ Y+FR  A N    S
Sbjct: 474  PTSSPKEDDIYYILEMEEEGSGYGFQPSYDGEELTCTIRNLNRSTKYKFRVAAYNSEGKS 533

Query: 1463 DASETTE 1469
            + S+  E
Sbjct: 534  NPSQVVE 540



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 6/74 (8%)

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
            S+ + ICWD P N G+    Y +    ++   + I +  +TK    IQ+L+ ++SYR R 
Sbjct: 880  STCLGICWDPPCNHGSEITSYSI----DLGERQPIVIGPVTK--HIIQHLQPDTSYRIRI 933

Query: 1454 YAVNEVDISDASET 1467
             A+N +     S T
Sbjct: 934  QALNSLGAGPFSHT 947



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 7/128 (5%)

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNILEIDSSSINICWDE 1403
            ++++  + +  ++++  N  G        T     SPP     P +   D +S  + W+ 
Sbjct: 1015 VQRLNESTSYTFRIQAFNEAGEGPFSTVYTFTTPRSPPAPVKAPKVERHDDNSCEVTWEA 1074

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
                    +IY +        +E+  +     T   IQ+L+ NS YRFR  AV E    D
Sbjct: 1075 LAPMRGDPVIYTL--QCMTGNSEFKQLYKGPGTSFHIQSLQLNSDYRFRVCAVRE--CQD 1130

Query: 1464 ASETTEYY 1471
            A E +  Y
Sbjct: 1131 APELSGPY 1138


>UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19;
            Euteleostomi|Rep: Protein sidekick-2 precursor - Homo
            sapiens (Human)
          Length = 2170

 Score =  106 bits (255), Expect = 6e-21
 Identities = 131/588 (22%), Positives = 220/588 (37%), Gaps = 33/588 (5%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXX 1535
            +P + +   + T      + L C   G P+P +TW +  + L +      + T       
Sbjct: 399  APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 458

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                        Y C+A N  G  E S  + +  +  IT   +D  Q    G +  +   
Sbjct: 459  LISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQD--QSVIKGTQASMVCG 516

Query: 1596 IEGIPPPEV--IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
            +   P   +  IW K+G  L  +    I   ++   + I +        YT    +  G 
Sbjct: 517  VTHDPRVTIRYIWEKDGATLGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGN 575

Query: 1654 SSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
             S    L+V   P  PE PV  +  + R ++ + W  P  DG   L +Y +E  E +N  
Sbjct: 576  DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAP 633

Query: 1713 W-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
            W + +A VD    +  ++ L     Y FR+ A N VG  +    +   +    + P+   
Sbjct: 634  WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ-FSKDTERVSLPEEPPTAPP 692

Query: 1772 XXXXXXXIDNESVYITWFP---SEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826
                     N+S+ I W P   S +NG     II Y +     G ++K           +
Sbjct: 693  QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 752

Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST-SRSVTLK 1885
            + L I T Y+  + A N  G  + Y+S  K+T       P+ P   V +E+T S ++   
Sbjct: 753  EDLIIWTNYEIEVAAYNSAGLGV-YSS--KVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 809

Query: 1886 WTEPESNGGSPITN--YIIEFKTVKGKSWTKIV---TVGGSVHEHCIENIKEKDEIIFRI 1940
            W  P     + I     +I ++  + +  T +        S+H   +  +K+  E    +
Sbjct: 810  WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 869

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
                T G    +  Q VR   H  VP  P   L    +    +  SW  P    G  L G
Sbjct: 870  LCFTTPGDGPRSTPQLVR--THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 925

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            Y I+  +  +T       +   TL++ +  L+   TY I + A    G
Sbjct: 926  YRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKG 973



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 110/522 (21%), Positives = 199/522 (38%), Gaps = 32/522 (6%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXXXXXX 1540
            V++P ++IT E  + +++ C   GVP P +TWY+D   ++  K T     N         
Sbjct: 309  VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGL 368

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                   ++C A N  GEV+TS  + +    P IT    D       G   ++     G 
Sbjct: 369  VPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACETSGA 426

Query: 1600 PPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            P P + W K    L +        T  E  S++ I     S +  YT  A+N+ G     
Sbjct: 427  PRPAITWQKGERILASGSVQLPRFTPLESGSLL-ISPTHISDAGTYTCLATNSRGVDEAS 485

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD-NNRWIKV 1716
              L V+ +    + P     I     ++      D       +Y  EK            
Sbjct: 486  ADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEKDGATLGTESHPR 543

Query: 1717 ADVDRDVETYCIQKLNENC-EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
              +DR+   +  Q  + +   Y  RVI+    G +++  S  + ++     P        
Sbjct: 544  IRLDRNGSLHISQTWSGDIGTYTCRVIS---AGGNDS-RSAHLRVRQLPHAPE--HPVAT 597

Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX---XXXXARIQKLSIN 1832
               ++  ++ +TW     +G SP+I Y +E+ +    W               ++ L   
Sbjct: 598  LSTVERRAINLTW-TKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPA 656

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW-TEPES 1891
             +YQFR+ A N++G        +++++ +   P + P+N + S  T++S+ ++W   PES
Sbjct: 657  RSYQFRLCAVNDVGKGQFSKDTERVSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPES 715

Query: 1892 NGGSPITNYIIEFKTV---KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
            +    +  YII +       G  +  I      V+   +E++         ++A N+ G 
Sbjct: 716  HQNGILKGYIIRYCLAGLPVGYQFKNI--TDADVNNLLLEDLIIWTNYEIEVAAYNSAG- 772

Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
             L   S  V       VP+ P   +      S  +  +W  P
Sbjct: 773  -LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAP 813



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 98/425 (23%), Positives = 175/425 (41%), Gaps = 50/425 (11%)

Query: 1658 VTLKVYDKPSKPEGPVIMRE-ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IK 1715
            VT +  D+P  P  P++ +E +   SV + W+P   DG   +  Y I+  E  + RW + 
Sbjct: 1390 VTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTRELPSGRWALH 1448

Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775
             A V  +  ++ + +L     Y FRV A N +G SE  E E   + T    P        
Sbjct: 1449 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE-ESESLTTLQAAPDEAPTILS 1507

Query: 1776 XXXIDNESVYITWFP-SEKNGGSPIIDYKVE----------------IKQEGKKW----- 1813
                   SV I W P +E      ++ +++                 I   G  W     
Sbjct: 1508 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1567

Query: 1814 ----KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869
                +           +  L+ +  Y+ R+   N +G   P +   ++ +G+ + P + P
Sbjct: 1568 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAP 1625

Query: 1870 RNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEF-KTVKGKSWTKIVTVGGSVHEHC 1926
            RN VV  +T+  + + W  P  +S  G  I  Y I F +  +G    ++ T+  + +   
Sbjct: 1626 RNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLTERVKTLFLAENSVK 1684

Query: 1927 IENIKEKDEIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
            ++N+      +  ++A N  G    S PT+ Q+         PS P++ ++   + +  V
Sbjct: 1685 LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT-----QQAAPSAPSS-VKFSELTTTSV 1738

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM-EVGKVDV---NTLKFNIRDLSENHTYMI 2039
              SW  P++  G  L GY +     +    + ++  VDV   + L   ++DL+E  TY  
Sbjct: 1739 NVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1797

Query: 2040 RIYAR 2044
            RI A+
Sbjct: 1798 RIRAK 1802



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 98/459 (21%), Positives = 189/459 (41%), Gaps = 36/459 (7%)

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC--ILRDESCTAEVTVVE 1104
            ++W++DG ++    +        H R+L I N +  D G Y C  +LR  S  + V    
Sbjct: 247  IIWKKDGVLLSGGISD-------HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 299

Query: 1105 L----PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGS--EIQFSNHIQLTI 1156
            L    PP+ +   +     +  K        KG     + W+KD +  E++     +   
Sbjct: 300  LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 359

Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
            DG    L+I     DD G + C      G  + +  L V   + N T R P    V    
Sbjct: 360  DGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT-RGPLDSTVIDGM 415

Query: 1213 DAYLTVEIPDETLD-VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
               L  E        +TW K + ++   + +    + ++  +L+I      D   YTC+ 
Sbjct: 416  SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 475

Query: 1271 LDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKI 1327
             +++   +   ++V +   +I    ++  + +G+  +++      P+      W  +   
Sbjct: 476  TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 535

Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387
            +    H +  +D ++ SL I +  + D G Y  R+ +  G+     ++ +   P  P  P
Sbjct: 536  LGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 594

Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNL 1443
               +  ++  +IN+ W +P + GNS +I Y++E  E +    + + ++    TS+  + L
Sbjct: 595  VATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 653

Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
                SY+FR  AVN+V     S+ TE   + +E     P
Sbjct: 654  VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 692



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 115/497 (23%), Positives = 204/497 (41%), Gaps = 47/497 (9%)

Query: 635  TFSKKPKAQYVDEGSDILLEC-RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            +F +  K Q V  G   ++   R+ + P+P + W   G +I P    ++ +E+ + +  +
Sbjct: 114  SFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSR-AITLENTLVILST 172

Query: 694  VLKITNVKKFQEGTYTVVAV---NREGEASLPIVLKIKT-GEKEP--PQVIEPLKSMIVR 747
            V           G Y V AV   N + + S PI L ++  G  +P  P +I P K+  V 
Sbjct: 173  VAP-------DAGRYYVQAVNDKNGDNKTSQPITLTVEVGGPADPIAPTIIIPPKNTSVV 225

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLK 806
             G S + + + V N RP I      K    L +    D    +TI  P    D G Y   
Sbjct: 226  AGTSEV-TLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTG-SDAGYY--- 280

Query: 807  AENSEGIAETSAVITVEEPTEENA-EPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSI 864
                E +  +S+V +V      +  EPP F+    + IT + +  + +  +    P PSI
Sbjct: 281  --ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI 338

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            TWY++  ++   E +T+     +  L I+ +  + D+G ++C A N+AG+      + + 
Sbjct: 339  TWYKDAAVVE-VEKLTRFRQRNDGGLQISGLVPD-DTGMFQCFARNAAGEVQTSTYLAVT 396

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRX 981
                   +    S    +G +V+L C+TS     +  W   ++ + SG            
Sbjct: 397  SIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 455

Query: 982  XXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037
                       D G   C+  +     E S  LVV        +  QD  V +   A + 
Sbjct: 456  GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMV 514

Query: 1038 VEINSE---TADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-- 1091
              +  +   T   +WE+DG  +  + + +   ++ G    L+I  T   D G Y+C +  
Sbjct: 515  CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVIS 571

Query: 1092 --RDESCTAEVTVVELP 1106
               ++S +A + V +LP
Sbjct: 572  AGGNDSRSAHLRVRQLP 588



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 77/298 (25%), Positives = 128/298 (42%), Gaps = 25/298 (8%)

Query: 633 PPTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           PP F K+P+     E   ++ + C+   +P P I W +K   +V  E ++   + +    
Sbjct: 305 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQRND--- 360

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              L+I+ +     G +   A N  GE      L + +    P     PL S ++  G S
Sbjct: 361 -GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVI-DGMS 416

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           V+L+ +  G PRP ITW K  + + +    LP  +  ++ S+ ++ P  + D G YT  A
Sbjct: 417 VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL-LISPTHISDAGTYTCLA 475

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI--T 865
            NS G+ E SA + V   T    +PP      Q+ +V +     +V  VT +P  +I   
Sbjct: 476 TNSRGVDEASADLVVWART-RITKPP------QDQSVIKGTQASMVCGVTHDPRVTIRYI 528

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           W ++   +          D  N  L I+   S  D G Y C   ++ G  S  A + +
Sbjct: 529 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSG-DIGTYTCRVISAGGNDSRSAHLRV 584



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 91/414 (21%), Positives = 157/414 (37%), Gaps = 19/414 (4%)

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G  S    ++ ++    P G +   EI   S+ + W+ P +  G+ LT Y I   E +  
Sbjct: 878  GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRT 936

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
                   +      Y +  L     Y   V A    G  + + +  I      ++P    
Sbjct: 937  NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPT 995

Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSP---IIDYKVEIKQEGKKW----KXXXXXXXXXA 1824
                   I   SV + + P      S    +++ +V +  EG++W    +          
Sbjct: 996  NLGISN-IGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSM 1054

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
             +  L+  T Y FR+   N +GTS P     KI   +   P   P N  +  ++  S+ L
Sbjct: 1055 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA-PPDMAPANVSLRTASETSLWL 1113

Query: 1885 KW---TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-HEHCIENIKEKDEIIFRI 1940
            +W    E E NG      Y I++    G   T    V   V  ++ IE+++E  E   ++
Sbjct: 1114 RWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQV 1173

Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLL 1999
             A N +G S P  SQ+V      +VPS     +      S+ ++  W   PE D    +L
Sbjct: 1174 QAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVL 1231

Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLK-FNIRDLSENHTYMIRIYARNEIGLSEP 2052
            GY +  ++           V+ N+ +   +  L +   Y +++ A   IG   P
Sbjct: 1232 GYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1285



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 33/120 (27%), Positives = 65/120 (54%), Gaps = 6/120 (5%)

Query: 1379 DKPSPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITK 1435
            D+P PP +P + + D  + S+ + W EP + G S + YY ++ +E+ +  W +   +++ 
Sbjct: 1396 DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSH 1454

Query: 1436 TQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
              +S  +  LK  +SY+FR  A N++  S+ SE +E    ++    ++PT+     + TT
Sbjct: 1455 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1514



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 86/392 (21%), Positives = 146/392 (37%), Gaps = 24/392 (6%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIEWK 1688
            I++L+     +  ++A N  G+     T+    + S P  GP  +  ++    S+ + W 
Sbjct: 1160 IEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 1219

Query: 1689 --PPLDDGGLELTKYAIEKHEPDNNR---WIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
              P  D  GL L    + K +  + +   W+   +  R  +   +  L +   Y  +V+A
Sbjct: 1220 EVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQ---LTGLGKYVLYEVQVLA 1276

Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803
               +G  +   S P +++  LD             +   SV + W P     G  I+ Y+
Sbjct: 1277 FTRIG--DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1333

Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQK----LSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
            +  +                +  Q     L   + Y FRI A+   G          +T 
Sbjct: 1334 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG-EAAEALVVTT 1392

Query: 1860 GKTLTPPSQPRNFVVSEST-SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT-KIVT 1917
             K   P    R  V  E   +RSV L W EP S+G SP+  Y I+ + +    W     +
Sbjct: 1393 EKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSAS 1451

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977
            V  +     ++ +K      FR+ A N +G S  +E         A     PT  L +  
Sbjct: 1452 VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTP 1510

Query: 1978 VGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV 2008
              +  V+  W  P  D     LLG+ I  R++
Sbjct: 1511 HTTTSVLIRWQPPAEDKINGILLGFRIRYREL 1542



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 2/74 (2%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
           V   CQ +G P P ITW++  A+++  +  +    +D    L I  + P+D G F C A+
Sbjct: 324 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGMFQCFAR 381

Query: 587 NAAGFASSTTELIV 600
           NAAG   ++T L V
Sbjct: 382 NAAGEVQTSTYLAV 395



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           DG +V   C+  G PRP ITW +   I+         +      +L+I      DAGT+T
Sbjct: 413 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 472

Query: 583 CVAKNAAGFASSTTELIVEA 602
           C+A N+ G   ++ +L+V A
Sbjct: 473 CLATNSRGVDEASADLVVWA 492



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 16/199 (8%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           I P  ++ P    V +G  ++L C     P P I W  KGE I+   ++ +   + +   
Sbjct: 398 IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESG 456

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
             ++  T++     GTYT +A N  G  EAS  +V+  +T   +PPQ         V +G
Sbjct: 457 SLLISPTHIS--DAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ------DQSVIKG 508

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTL 805
               +   V  +PR TI +    K    L T+S      D +    +      D G YT 
Sbjct: 509 TQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 567

Query: 806 KAENSEGIAETSAVITVEE 824
           +  ++ G    SA + V +
Sbjct: 568 RVISAGGNDSRSAHLRVRQ 586



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%)

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV---YDKPSKPEGPVIMREISRESVTIE 1686
            +++K+L    + ++ I A        +E  +        P  P  P+I+R  S  ++ I 
Sbjct: 1784 LKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS--AIAIH 1841

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQK--LNENCEYMFRVIA 1743
            W    D G   +T+Y IE    D   W I + D+ ++V +Y      L     Y FRVIA
Sbjct: 1842 WSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1900

Query: 1744 QNPVGF 1749
             N  GF
Sbjct: 1901 VNDYGF 1906



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 44/144 (30%), Positives = 67/144 (46%), Gaps = 13/144 (9%)

Query: 1337 SIDSKSASLTIKKVENTDAGI---YKLRLENNCGHADVEMNVTI---LDKPSPPGKPNIL 1390
            ++D K  S    KV++   G+   +++R +      ++E NVT       P PPG P I+
Sbjct: 1773 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIV 1832

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTS----IQNLKT 1445
               SS+I I W   +  G   I  YV+E +  D   W I +K+I K  +S    +  LK 
Sbjct: 1833 RY-SSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1890

Query: 1446 NSSYRFRAYAVNEVDISDASETTE 1469
              SY FR  AVN+      S  ++
Sbjct: 1891 GVSYDFRVIAVNDYGFGTPSSPSQ 1914


>UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|Rep:
            ENSANGP00000009916 - Anopheles gambiae str. PEST
          Length = 1448

 Score =  106 bits (254), Expect = 8e-21
 Identities = 119/494 (24%), Positives = 211/494 (42%), Gaps = 50/494 (10%)

Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            D  IL  + + + T +++W +D   + P      F     +R   IR+    D G+Y+CI
Sbjct: 270  DSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRH---EDIGDYTCI 326

Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141
             R+     S TA V      V+ +PP   T+L+ +KV    + T E +   G+  VRWF+
Sbjct: 327  ARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKV----QFTCEAKAMPGNVTVRWFR 382

Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS 1195
            +GS ++    ++  +  +K   L I     DD+G+Y+CEV N        +A L +E P+
Sbjct: 383  EGSPVREVAALETRVTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPA 442

Query: 1196 -INFTLRLPEF-ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
             + FT  +      +      Y+    P +   VTW K K ++E  +   ++  +   +L
Sbjct: 443  KVTFTPTIQYLPFRLAGVVQCYIKANPPLQY--VTWTKDKRLLEPYQTKDIVI-MNNGSL 499

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
            +  +  ++ Q  YTC   +A+ T      ++V V + P   V+ +  Y+ K G  V +  
Sbjct: 500  LFTRVNQNHQGRYTCTPYNAQGTQGSSGHMEVLVRKPPAFTVEPDPLYQRKVGESVEMHC 559

Query: 1310 DYQ---AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366
            D Q      +PN +W    +  +  +  +  I+  S ++TI+ +  +D G Y+    N  
Sbjct: 560  DAQEAEGTSKPNIQW--QRRDGQPLQKNRVRIN--SGNITIENLRRSDFGYYQCVASNEV 615

Query: 1367 GHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
                V     +++   P    N+       S+ + W    + G      Y + Y+E   +
Sbjct: 616  A-TIVSATQLVIEGTQPHAPYNLSGSATEFSVTLSWMPGYSGGPDYKQDYTIWYREAGVS 674

Query: 1426 EW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483
            EW  I V     TQ +I  L   ++Y F+    N +     S      KVI    + +  
Sbjct: 675  EWSTIPVTPSGSTQVTINRLSPGTTYEFQVIGKNALGDGMMS------KVITIRTLDAQK 728

Query: 1484 VEKPLKNITTEPNE 1497
             +KP    T  PN+
Sbjct: 729  AKKP-STTTAAPND 741



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 77/333 (23%), Positives = 134/333 (40%), Gaps = 25/333 (7%)

Query: 633 PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           PP FS  P+   YV+ G  I+L C+    P P+I W      + P   + +  +      
Sbjct: 253 PPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDG----- 307

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            + L+I+ ++    G YT +A N EG+ S    + I  G      ++ P  +    +GE 
Sbjct: 308 -TELRISTIRHEDIGDYTCIARNGEGQVSHTARVIIAGG----AVIMVPPTNQTKLEGEK 362

Query: 752 VILSAQVVGNP-RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           V  + +    P   T+ W +   PV+   AL T+         I+ P    D G YT + 
Sbjct: 363 VQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKDGSLIINPVSADDSGQYTCEV 422

Query: 808 ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            N  G  ++ SA + +E P +    P +     Q +  +  G ++   +    P+  +TW
Sbjct: 423 SNGIGEPQSASAYLNIEYPAKVTFTPTI-----QYLPFRLAGVVQCYIK-ANPPLQYVTW 476

Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
            ++  ++ P +T        N  L+ T V+     G Y C   N+ G       + + V 
Sbjct: 477 TKDKRLLEPYQT-KDIVIMNNGSLLFTRVNQN-HQGRYTCTPYNAQGTQGSSGHMEVLVR 534

Query: 927 K-VTFVKHLQKSYETEEGKTVILECQTSHTVST 958
           K   F       Y+ + G++V + C       T
Sbjct: 535 KPPAFTVEPDPLYQRKVGESVEMHCDAQEAEGT 567



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 70/252 (27%), Positives = 109/252 (43%), Gaps = 24/252 (9%)

Query: 695 LKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           L +T++++  +G Y   VV +NR  +               P   + P   + V  G+S+
Sbjct: 213 LNLTDIRESDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSI 272

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLKAENS 810
           IL+ Q  G P P I W K+  PV   P+ + G  +  T L+   ++ E  G YT  A N 
Sbjct: 273 ILNCQADGTPTPEILWYKDANPVD--PSSTVGIFNDGTELRISTIRHEDIGDYTCIARNG 330

Query: 811 EG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
           EG ++ T+ VI           PP    + +     EK      A+     V ++ W+R 
Sbjct: 331 EGQVSHTARVIIAGGAV--IMVPPTNQTKLE----GEKVQFTCEAKAMPGNV-TVRWFRE 383

Query: 870 ----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK-SSHGARVTID 924
                E+ +    +T   DG    L+I  V ++ DSG Y C  SN  G+  S  A + I+
Sbjct: 384 GSPVREVAALETRVTIRKDG---SLIINPVSAD-DSGQYTCEVSNGIGEPQSASAYLNIE 439

Query: 925 V-EKVTFVKHLQ 935
              KVTF   +Q
Sbjct: 440 YPAKVTFTPTIQ 451



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 94/409 (22%), Positives = 153/409 (37%), Gaps = 58/409 (14%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G ++   CQ +G P P+I W++    + PS    ++ D   +    IR    ED G +TC
Sbjct: 269 GDSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRH---EDIGDYTC 325

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           +A+N  G  S T  +I+       G  + +                  +PPT   K    
Sbjct: 326 IARNGEGQVSHTARVIIA------GGAVIM------------------VPPTNQTKL--- 358

Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEI--VPDENISVAIESDMHMYCSVLKITNV 700
              EG  +   C   A+P    + W  +G  +  V      V I  D       L I  V
Sbjct: 359 ---EGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKD-----GSLIINPV 410

Query: 701 KKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
                G YT    N  GE  S    L I+   K       P    +  +   V+      
Sbjct: 411 SADDSGQYTCEVSNGIGEPQSASAYLNIEYPAK---VTFTPTIQYLPFRLAGVVQCYIKA 467

Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSA 818
             P   +TW K+ + ++   TK     ++ ++L  +     +G YT    N++G   +S 
Sbjct: 468 NPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNHQGRYTCTPYNAQGTQGSSG 527

Query: 819 --VITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
              + V +P     EP PL+  +  E +V+     +     ++   P+I W R +    P
Sbjct: 528 HMEVLVRKPPAFTVEPDPLYQRKVGE-SVEMHCDAQEAEGTSK---PNIQWQRRDG--QP 581

Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            +      +  NI   I N+    D G Y+CVASN         ++ I+
Sbjct: 582 LQKNRVRINSGNI--TIENL-RRSDFGYYQCVASNEVATIVSATQLVIE 627



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 20/264 (7%)

Query: 1509 PQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--C 1563
            P   VTW +D + L+   T      N                Y C  +N  G   +S   
Sbjct: 470  PLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNHQGRYTCTPYNAQGTQGSSGHM 529

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLV---TAVIEGIPPPEVIWYK-NGNKLENDKEY 1619
             V +++ P  T+  + + Q+ KVG+   +       EG   P + W + +G  L+ ++  
Sbjct: 530  EVLVRKPPAFTVEPDPLYQR-KVGESVEMHCDAQEAEGTSKPNIQWQRRDGQPLQKNR-- 586

Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
                +  +  I I+ L+RS    Y   ASN   T  V  T  V +  ++P  P  +   +
Sbjct: 587  ---VRINSGNITIENLRRSDFGYYQCVASNEVATI-VSATQLVIEG-TQPHAPYNLSGSA 641

Query: 1680 RE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
             E SVT+ W P    G      Y I   E   + W  +           I +L+    Y 
Sbjct: 642  TEFSVTLSWMPGYSGGPDYKQDYTIWYREAGVSEWSTIPVTPSGSTQVTINRLSPGTTYE 701

Query: 1739 FRVIAQNPVGFSEALESEPIVIKT 1762
            F+VI +N +G  + + S+ I I+T
Sbjct: 702  FQVIGKNALG--DGMMSKVITIRT 723



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 38/161 (23%), Positives = 64/161 (39%), Gaps = 8/161 (4%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFN 1554
            + I L C   G P P++ WY+D   +  +     + +                Y CIA N
Sbjct: 270  DSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRHEDIGDYTCIARN 329

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI-WYKNGNKL 1613
              G+V  +  V I    VI +      Q    G++   T   + +P    + W++ G+ +
Sbjct: 330  GEGQVSHTARVIIAGGAVIMV--PPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPV 387

Query: 1614 EN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                  E  +T ++  S+I I  +    S +YT E SN  G
Sbjct: 388  REVAALETRVTIRKDGSLI-INPVSADDSGQYTCEVSNGIG 427



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
            +   P  +++ EDI   + +GD  ++    +G P PE++WYK+ N +  D    +     
Sbjct: 250  VHAPPRFSVTPEDIIYVN-LGDSIILNCQADGTPTPEILWYKDANPV--DPSSTVGIFND 306

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
             + +RI  ++      YT  A N  G  S
Sbjct: 307  GTELRISTIRHEDIGDYTCIARNGEGQVS 335



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           +G  VQF C+ +  P    + WFR+ + ++     +         +L+I  V  +D+G +
Sbjct: 359 EGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKDGSLIINPVSADDSGQY 418

Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603
           TC   N  G   S++  L +E P
Sbjct: 419 TCEVSNGIGEPQSASAYLNIEYP 441


>UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=23;
           Euteleostomi|Rep: Transmembrane receptor Roundabout3 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1419

 Score =  105 bits (252), Expect = 1e-20
 Identities = 98/372 (26%), Positives = 159/372 (42%), Gaps = 28/372 (7%)

Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664
           SD G  + V            A+++    P F ++P  Q V     +  +C +   P P 
Sbjct: 228 SDAGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPT 287

Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
           I W  K E  +P     +  ++        L++T VK   EG+YT ++ N  G+A     
Sbjct: 288 IRWK-KEEGELPRGRFEIRADNS-------LRLTQVKAEDEGSYTCLSENSVGKAEASGS 339

Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK--S 782
           L++      PPQ++   +  I  QG +V       GNP P + W K    V   P++  S
Sbjct: 340 LQVHV----PPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPS 395

Query: 783 DGDTHSITI-----LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
                S+++     +     +D G Y  +A +  G   T A++ VE  T  +  PP+   
Sbjct: 396 QSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVES-TPSDRIPPIIRQ 454

Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELVITNVD 896
                T+    T +L   V  NP+PSI W R+ + I+   E I+     EN  L IT + 
Sbjct: 455 GPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLM---ENGTLQITAL- 510

Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSH 954
            E DSG Y CVAS+ +G++S    +T+          + + Y+      K V+ +  T +
Sbjct: 511 QETDSGAYTCVASSLSGETSWSGVLTVKESGGLSASPVSEPYQLPGPPQKPVVTDV-TRN 569

Query: 955 TVSTKWYHNKKE 966
           +V+  W  N  E
Sbjct: 570 SVTLTWQPNAHE 581



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 112/485 (23%), Positives = 181/485 (37%), Gaps = 44/485 (9%)

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD----ENISVAI 684
            LE   P   + P    V +G    L C+    P P + W   GE +  D     +  + +
Sbjct: 58   LEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLL 117

Query: 685  ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKS 743
             S    +  ++     K   EG Y  VA N  GEA S    L++     +  Q   P   
Sbjct: 118  PSGSLFFLRIVHGRRSKP-DEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQT--P-SD 173

Query: 744  MIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802
            ++V  GE  ++      G+P PTI+W +NN  V     +       + I   +K  D G+
Sbjct: 174  VVVAAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDERITIRGGKLMISNTRK-SDAGM 232

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y     N  G  ++     V        E P+F+ R     V    T+     V  +P P
Sbjct: 233  YVCVGTNMVGEKDSDPAELVV------FERPMFVRRPVNQVVLADDTVDFQCEVQGDPAP 286

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            +I W +  E   P        D     L +T V +E D G Y C++ NS GK+     + 
Sbjct: 287  TIRW-KKEEGELPRGRFEIRADN---SLRLTQVKAE-DEGSYTCLSENSVGKAEASGSLQ 341

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGR 980
            + V     V+   +   + +G+TV   C T  +   +  W     ++     +   Q GR
Sbjct: 342  VHVPPQIVVR--PRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGR 399

Query: 981  XXXXXXXXXXXXDV-----GVIKC----IVKDQETSTMLVVKET----IPEFIRK-LQDF 1026
                        DV     G   C    +     T  +L V+ T    IP  IR+   + 
Sbjct: 400  FSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQ 459

Query: 1027 EVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
             +     A L+  +  +    + WERDG+ I     +    + G ++   ++ T   D G
Sbjct: 460  TLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQET---DSG 516

Query: 1086 EYSCI 1090
             Y+C+
Sbjct: 517  AYTCV 521



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 89/365 (24%), Positives = 155/365 (42%), Gaps = 48/365 (13%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P+FV +   +      TV F+C+V+G P P I W ++   + P   F++  D+    +L 
Sbjct: 257 PMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEGEL-PRGRFEIRADN----SLR 311

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
           + +V  ED G++TC+++N+ G A ++  L V  P      ++ V               L
Sbjct: 312 LTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVP-----PQIVVRPRDQISAQGRTVTFL 366

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            G     +  P   +  EGS +L               LF  +        SV++  +  
Sbjct: 367 CGTKG--NPPPAVFWQKEGSQVL---------------LFPSQPPSQSGRFSVSLSGE-- 407

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEPLKSMIVR 747
                L IT+V     G Y   A++  G      +L++++   ++ PP + +   +  + 
Sbjct: 408 -----LTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLA 462

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYT 804
            G +  L   V+GNP P+I W ++ + +  +  +    +  T  IT L+     D G YT
Sbjct: 463 PGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQE---TDSGAYT 519

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A +  G    S V+TV+E    +A P      +Q     +K    +V  VTRN V ++
Sbjct: 520 CVASSLSGETSWSGVLTVKESGGLSASP--VSEPYQLPGPPQK---PVVTDVTRNSV-TL 573

Query: 865 TWYRN 869
           TW  N
Sbjct: 574 TWQPN 578



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 169/845 (20%), Positives = 312/845 (36%), Gaps = 86/845 (10%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASL 1345
            P+IV++  +  + +G   TL    +  P P  EW  + + ++  +    S  +   S SL
Sbjct: 63   PRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGSL 122

Query: 1346 TIKKV-----ENTDAGIYKLRLENNCGHA---DVEMNVTIL-DKPSPPGKPNILEIDSSS 1396
               ++        D G+Y     N  G A   +  + V IL D         ++     +
Sbjct: 123  FFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEPA 182

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            +  C   P      TI +     +  D  E I+++     +  I N + + +  +     
Sbjct: 183  VMEC-IPPRGHPEPTISWKRNNVKVNDKDERITIRG---GKLMISNTRKSDAGMYVCVGT 238

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N V   D S+  E   V+ E  +    V +P+  +    ++ ++  C   G P P + W 
Sbjct: 239  NMVGEKD-SDPAEL--VVFERPM---FVRRPVNQVVL-ADDTVDFQCEVQGDPAPTIRWK 291

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            ++  +L   +                     Y C++ N  G+ E S  + +   P I + 
Sbjct: 292  KEEGELPRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQIVVR 351

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-----ENDKEYNITTKEKTSVIR 1631
              D  Q    G         +G PPP V W K G+++     +   +    +   +  + 
Sbjct: 352  PRD--QISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELT 409

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691
            I ++    S  Y  +A + AG+   +  L+V   PS    P+I +  + +++       L
Sbjct: 410  ITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQL 469

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE--TYCIQKLNENCEYMFRVIAQN---- 1745
                +     +I+  E D  R + + +    +E  T  I  L E     +  +A +    
Sbjct: 470  QCHVMGNPLPSIQ-WERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGE 528

Query: 1746 -------PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798
                    V  S  L + P+     L  P           +   SV +TW P+   GG+ 
Sbjct: 529  TSWSGVLTVKESGGLSASPVSEPYQLPGPP---QKPVVTDVTRNSVTLTWQPNAHEGGAA 585

Query: 1799 IIDYKVEI--KQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            +  Y +E   +  G  W+            +  LS NT Y F + A N  G S P    +
Sbjct: 586  VTSYIIEAFSQSAGSTWQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPISE 645

Query: 1856 KITIGKTLTPPSQ--PRNFVVSE-------------STSRSVTLKWTEPESNGGSPITNY 1900
             +   + ++P  Q      V  E              T+ SV + W     +    I  Y
Sbjct: 646  PVRT-QDVSPTGQGVDHRQVQRELGEMSVQLHEPVLLTASSVKISWNVDRQS--QYIQGY 702

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
             + ++ V G SW++    G +     I N+ +  E   +I         L + SQ++R  
Sbjct: 703  RLLYRPV-GGSWSQQEVKGATERSAVIANLLKGTEYEIKIRPYFNEFQGLDSRSQTLRTP 761

Query: 1961 KHATVPS-PPTA--PLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNI-AIRDVTKTMWME 2015
            +   VPS PP A     +++  S+ +  SW  P  D     +  Y +  + + ++T +  
Sbjct: 762  EE--VPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKVWCLGNDSQTRYNI 819

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL---SEP------LESDEPFKVIPGEG 2066
               VD + L   ++ L     Y + + A    G+   S+P      L +++P   + G G
Sbjct: 820  NQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPVSVLIKLPAEQP--TVTGGG 877

Query: 2067 SHADE 2071
            S ++E
Sbjct: 878  SESEE 882



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 117/535 (21%), Positives = 202/535 (37%), Gaps = 54/535 (10%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--------LPTKS 782
            E   P+++E    +IV +GE   L+ +  G P P + W K+ + V+              
Sbjct: 59   EDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLP 118

Query: 783  DGDTHSITILKPKKVK-DEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQ 840
             G    + I+  ++ K DEGVY   A N  G A   +A + V    ++  + P  +    
Sbjct: 119  SGSLFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDV---- 174

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             +   E   ++ +     +P P+I+W RNN  ++  +   +       +L+I+N   + D
Sbjct: 175  VVAAGEPAVMECIP-PRGHPEPTISWKRNNVKVNDKD---ERITIRGGKLMISNT-RKSD 229

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVST 958
            +G Y CV +N  G+        +  E+  FV+         +  TV  +C  Q     + 
Sbjct: 230  AGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLAD-DTVDFQCEVQGDPAPTI 288

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKE 1014
            +W   KKE  G   R   +               D G   C+    V   E S  L V  
Sbjct: 289  RW---KKE-EGELPRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHV 344

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE--IIKPKKNKYDFEKRGHIR 1072
                 +R       + + V  L     +    V W+++G   ++ P +      +     
Sbjct: 345  PPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSL 404

Query: 1073 KLYIRNTSVH--DEGEYSC--------ILRDESCTAEVTVVE-LPPEIITRLQNQKVNKG 1121
               +  T VH  D G Y C        IL       E T  + +PP I     NQ +  G
Sbjct: 405  SGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPG 464

Query: 1122 NKATFEIELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
              A  +  +  G+ L  ++W +DG  I      I L  +G    L+I      D+G Y+C
Sbjct: 465  TTAQLQCHV-MGNPLPSIQWERDGQRILGIDERISLMENG---TLQITALQETDSGAYTC 520

Query: 1179 EV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
                  G +  + +LTV+E        + E   +P      +  ++   ++ +TW
Sbjct: 521  VASSLSGETSWSGVLTVKESGGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTW 575



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 69/248 (27%), Positives = 103/248 (41%), Gaps = 37/248 (14%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDF 556
           E   S +  + P  V + R + +  G TV F C  +G P P + W ++    ++ PSQ  
Sbjct: 335 EASGSLQVHVPPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPP 394

Query: 557 QM--YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614
                +       L I +V  ED+G + C A + AG   +   L VE+  SD        
Sbjct: 395 SQSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDR------- 447

Query: 615 XXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
                            IPP   + P  Q +  G+   L+C ++  P P I W   G+ I
Sbjct: 448 -----------------IPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRI 490

Query: 675 VP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEK 732
           +  DE IS+       M    L+IT +++   G YT VA +  GE S   VL +K +G  
Sbjct: 491 LGIDERISL-------MENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKESGGL 543

Query: 733 EPPQVIEP 740
               V EP
Sbjct: 544 SASPVSEP 551



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 84/374 (22%), Positives = 147/374 (39%), Gaps = 37/374 (9%)

Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK-----PKKNKYDF 1065
            +++  P  +    D  V + + A L  +       +V W +DGE ++     P+ ++   
Sbjct: 58   LEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLL 117

Query: 1066 EKRG--HIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKV 1118
                   +R ++ R  S  DEG Y C+ R+      S  A + V  L  +      +  V
Sbjct: 118  PSGSLFFLRIVHGRR-SKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVV 176

Query: 1119 NKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
              G  A  E    +G  +  + W ++  ++   +  ++TI G K  L I +    DAG Y
Sbjct: 177  AAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDE-RITIRGGK--LMISNTRKSDAGMY 233

Query: 1177 SCE----VG--NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230
             C     VG  +S    ++  E P     +R P   +V A+       E+  +      +
Sbjct: 234  VCVGTNMVGEKDSDPAELVVFERPMF---VRRPVNQVVLADDTVDFQCEVQGDPAPTIRW 290

Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPK 1289
            KK+       +F + +D    +L + +   +D+  YTC+  ++    +    + V  PP+
Sbjct: 291  KKEEGELPRGRFEIRAD---NSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQ 347

Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-----SKSAS 1344
            IV   R+    +G  VT L   +  P P   W      +       PS       S S  
Sbjct: 348  IVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGE 407

Query: 1345 LTIKKVENTDAGIY 1358
            LTI  V + D+G Y
Sbjct: 408  LTITDVHSEDSGYY 421



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
           + E  ++    + PI  +    +    G+T Q +C V G P P I W R    I    + 
Sbjct: 437 LLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDER 496

Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
               ++    TL I  +   D+G +TCVA + +G  S +  L V+
Sbjct: 497 ISLMEN---GTLQITALQETDSGAYTCVASSLSGETSWSGVLTVK 538


>UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2;
            n=6; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to sidekick-2 - Strongylocentrotus purpuratus
          Length = 2931

 Score =  105 bits (251), Expect = 2e-20
 Identities = 144/654 (22%), Positives = 251/654 (38%), Gaps = 45/654 (6%)

Query: 1379 DKPSPPGKPNI--LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436
            ++P PP   N+    I S S+ + +  P   GN+ I  + V+     +  W +V  ++ +
Sbjct: 965  ERPQPPTNLNVPGSTIQSRSVQLHFT-PGLDGNAGITLWTVQGLIGQSDRWETVFELSDS 1023

Query: 1437 QT---SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP------TVEKP 1487
                  I  L+  + Y+FR  A N    S+ SE +E  +  ++    +P           
Sbjct: 1024 SARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSEQIQTDQDVPAIAPRDVRVRAFNAT 1083

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547
               +T  P +D E   + GG    ++ W   G  ++       +                
Sbjct: 1084 ALRVTWMPLDDTEWNGVPGGY---RIYWKPYGTNMQEMIFDLASPYINNHVIGGLEEWMP 1140

Query: 1548 Y--KCIAFND-HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-----AVIEG- 1598
            Y  +  A+N+ H    +  V G   + V +    +I+       E + T     A+ +  
Sbjct: 1141 YDVRIEAYNEQHSGPTSGMVAGWTNEAVPSAGPSNIQALPIYYSEIMATWGDVPAIHQNG 1200

Query: 1599 -IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV- 1656
             I   +VI+ +NG  L        TT+E T    I  LK       T+ A    G   + 
Sbjct: 1201 EILGFKVIFRENGGILMYLDVPGNTTREAT----ITHLKGYTVYTITVLAYTVVGDGVIG 1256

Query: 1657 -EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWI 1714
             EV ++ ++    P G +    +   SVTI W  PL   G++LT K          N  +
Sbjct: 1257 NEVPVRTHEWFPGPPGGITFPTVQESSVTIAWNEPLLPNGVDLTYKVGYRLQAAPANTLV 1316

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            +  +V    E + +  L     Y F V A    GF +   +  +VI T            
Sbjct: 1317 E-ENVGGSRE-HTVAGLMPEETYYFEVTASTLTGFGQ--PASALVITTTDRTAPEAPSKP 1372

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW---KXXXXXXXXXARIQKLSI 1831
                I +  V ++W P   NG SP+  Y ++++ +   W               +  L+ 
Sbjct: 1373 TVDHIKSRQVRLSWTPG-NNGNSPLRYYIIDVRVDSGPWAQHSMTVDASQVSYIVTGLNP 1431

Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-E 1890
            +T Y FR+   N+IG S    + D+ T  + + P   P     +  T  S+ + W  P +
Sbjct: 1432 HTLYYFRLKVYNDIGASPESPTSDQTTTEQDI-PEGVPTITGATPITVTSLLVTWQPPLQ 1490

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
            +    P+T Y  +F+ + G S+ +       V EH + N+        +++A N++G  L
Sbjct: 1491 AQTNGPLTGYSFQFRQLPGGSFMEETISDAGVTEHELLNLVRYQNYEVKLAATNSIG--L 1548

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNI 2003
               S  V +     VPS P + + +   GS+    SW  P  +     L GY +
Sbjct: 1549 GPYSAPVYVYIGEAVPSEPPSAVTVATTGSSAFQISWVPPSTESQNGGLQGYKV 1602



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 170/838 (20%), Positives = 300/838 (35%), Gaps = 60/838 (7%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTL--LV 1309
            L++++  ++D  EYTC+  +  +T      ++ +   ++  +    +   G   TL  +V
Sbjct: 537  LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVISQKPTSVQTILGETTTLNCVV 596

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
             + +   P   W+ +  +I         I  +S SL I   +  D G+Y  ++ +  G  
Sbjct: 597  QHDSRVTPTVTWMQDGGVIIP---NGRFIIQESGSLVILSTDANDMGLYVCKVTSIAGDD 653

Query: 1370 DVEMNVTILDKP-SPPGKPNILEIDSS-SINICWDEPENTGNSTIIYYVVEYQEIDT--T 1425
                N+T+L  P  P G       D   +I + W  P   GNS +I Y++E +E D+  T
Sbjct: 654  LGSANLTVLQVPYQPQGVTATKSQDQDRTIIVSW-LPVFDGNSALIRYILEQKEDDSAFT 712

Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
            E  +  N   TQ  +  ++ +  Y++R  A N + +S+ SE +    + +E     PT  
Sbjct: 713  EVEATINPLLTQFLVTGVRPSRRYQYRLRAQNAIGMSEKSEASNVVHLPEEL----PTA- 767

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXX 1544
             P + +            IF   P   +     G KL   +   E N             
Sbjct: 768  -PPQEVDIVVTSSTSFMYIFSSPPVQFINGINQGYKLLAWEPGMESNPITELVPPNVAQS 826

Query: 1545 XXXYKCIAFNDHGEVETSCVV------GIQQKPVITISNEDIK---QKHKVGDEWLVTAV 1595
                         E + S +       G+   PV  +++ED+        + + +  +  
Sbjct: 827  RFIGNITTLKKFTEYQASVLCYTNPGDGVPSTPVTLMTHEDVPGPVSNLGLNNVYDTSVQ 886

Query: 1596 IEGIPPPEVIWYKNGNKL---ENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
            +    P EV    +G  +   E+++    YN   K   +   I  L    +    + A  
Sbjct: 887  VSWEQPQEVNGALSGYSISWQEHNRTSNIYNANRKPNETSYTITALTPDTTYLIQVWAKT 946

Query: 1650 TAGTS-SVEVTLKVYDKPSKPEGPVIMR----EISRESVTIEWKPPLDDGGLELTKYAIE 1704
            + G   + ++ +     P +P+ P  +      I   SV + + P L DG   +T + ++
Sbjct: 947  SVGPGPTTDIIISSGIPPERPQPPTNLNVPGSTIQSRSVQLHFTPGL-DGNAGITLWTVQ 1005

Query: 1705 KHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
                 ++RW  V ++ D    +  I  L     Y FR+IA N  G S   E     I+T 
Sbjct: 1006 GLIGQSDRWETVFELSDSSARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSE-QIQTD 1064

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXX 1822
             DVP+           +  ++ +TW P +    + +   Y++  K  G   +        
Sbjct: 1065 QDVPAIAPRDVRVRAFNATALRVTWMPLDDTEWNGVPGGYRIYWKPYGTNMQEMIFDLAS 1124

Query: 1823 ----XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   I  L     Y  RI A NE   S P TS           P + P N       
Sbjct: 1125 PYINNHVIGGLEEWMPYDVRIEAYNE-QHSGP-TSGMVAGWTNEAVPSAGPSNIQALPIY 1182

Query: 1879 SRSVTLKWTE-PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937
               +   W + P  +    I  + + F+   G     +   G +  E  I ++K      
Sbjct: 1183 YSEIMATWGDVPAIHQNGEILGFKVIFRE-NGGILMYLDVPGNTTREATITHLKGYTVYT 1241

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
              + A   VG  +      VR   H   P PP   +    V  + V  +W  P    G  
Sbjct: 1242 ITVLAYTVVGDGVIGNEVPVR--THEWFPGPP-GGITFPTVQESSVTIAWNEPLLPNGVD 1298

Query: 1998 L---LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            L   +GY +        +   VG     + +  +  L    TY   + A    G  +P
Sbjct: 1299 LTYKVGYRLQAAPANTLVEENVG----GSREHTVAGLMPEETYYFEVTASTLTGFGQP 1352



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 92/409 (22%), Positives = 160/409 (39%), Gaps = 30/409 (7%)

Query: 1669 PEG-PVIM--REISRESVTIEWKPPLD-DGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
            PEG P I     I+  S+ + W+PPL       LT Y+ +  +     +++    D  V 
Sbjct: 1464 PEGVPTITGATPITVTSLLVTWQPPLQAQTNGPLTGYSFQFRQLPGGSFMEETISDAGVT 1523

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + +  L     Y  ++ A N +G      S P+ +     VPS            + + 
Sbjct: 1524 EHELLNLVRYQNYEVKLAATNSIGLGPY--SAPVYVYIGEAVPSEPPSAVTVATTGSSAF 1581

Query: 1785 YITWFP---SEKNGGSPIIDYKVEIKQEGKKWKXXXX--------XXXXXARIQKLSINT 1833
             I+W P     +NGG  +  YKV   +   +                   A +  L   T
Sbjct: 1582 QISWVPPSTESQNGG--LQGYKVLYWENHSRQARATIVQQTKTFPASATVATLDDLECFT 1639

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
             Y   +   N  G   P +     T G+ +  PS+  +   S+    S+ + W  P S  
Sbjct: 1640 EYGISVKGFNAAGDG-PGSPTSYSTTGEDV--PSEVSSLQFSQVRMSSLKVSWGPPTSPC 1696

Query: 1894 GSPITNYII--EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            G+ I   +     + + G+  + +VT+    + +  + + E++  +F + AE T     P
Sbjct: 1697 GTIIQYKLFYQPHEPINGERTSVVVTLPSDQYSYVAKRLGERERYLFEVHAE-TASFEGP 1755

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
               Q++        P  PT  ++    GS+ +  SW    + G  PL+GY I  ++  + 
Sbjct: 1756 RRGQNITTGPQEGAPDSPTN-IDXSP-GSSFLTVSWEELVFHGDNPLIGYIIQSQEKGQD 1813

Query: 2012 MWMEVG-KVDVNTLKFNI--RDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             W  V   +  N  +F+I    L     Y  R+ A +EI +SEP  S+E
Sbjct: 1814 TWENVNDTIGANQSQFSIPYSSLDPVTVYTFRVMAESEISVSEPAPSEE 1862



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 120/607 (19%), Positives = 225/607 (37%), Gaps = 39/607 (6%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX- 1539
            +P +     + T    E   L C   G P P + W +DG+ + +A     +R        
Sbjct: 477  APEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQTFGN 536

Query: 1540 -----XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y CIA N      +S  + + Q+ VI  S +    +  +G+   +  
Sbjct: 537  LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVI--SQKPTSVQTILGETTTLNC 594

Query: 1595 VIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            V++      P V W ++G  +  +  + I  +E  S++ I     +    Y  + ++ AG
Sbjct: 595  VVQHDSRVTPTVTWMQDGGVIIPNGRFII--QESGSLV-ILSTDANDMGLYVCKVTSIAG 651

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
                   L V   P +P+G    +   ++ ++ + W P  D G   L +Y +E+ E D+ 
Sbjct: 652  DDLGSANLTVLQVPYQPQGVTATKSQDQDRTIIVSWLPVFD-GNSALIRYILEQKEDDSA 710

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
                 A ++  +  + +  +  +  Y +R+ AQN +G SE  E+   V+    ++P+   
Sbjct: 711  FTEVEATINPLLTQFLVTGVRPSRRYQYRLRAQNAIGMSEKSEASN-VVHLPEELPTAPP 769

Query: 1772 XXXXXXXIDNES-VYITWFPSEK-----NGGSPIIDYK--VEIKQEGKKWKXXXXXXXXX 1823
                     + S +YI   P  +     N G  ++ ++  +E     +            
Sbjct: 770  QEVDIVVTSSTSFMYIFSSPPVQFINGINQGYKLLAWEPGMESNPITELVPPNVAQSRFI 829

Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883
              I  L   T YQ  +      G  +P T    +T+      P    N  ++     SV 
Sbjct: 830  GNITTLKKFTEYQASVLCYTNPGDGVPST---PVTLMTHEDVPGPVSNLGLNNVYDTSVQ 886

Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
            + W +P+   G+ ++ Y I ++     S         +   + I  +      + ++ A+
Sbjct: 887  VSWEQPQEVNGA-LSGYSISWQEHNRTSNIYNANRKPNETSYTITALTPDTTYLIQVWAK 945

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS---WGTPEWDGGAPLLG 2000
             +VG    T+     +      P  P  P  + + GS I   S     TP  DG A +  
Sbjct: 946  TSVGPGPTTDI----IISSGIPPERPQPPTNLNVPGSTIQSRSVQLHFTPGLDGNAGITL 1001

Query: 2001 YNIAIRDVTKTMWMEVGKV-DVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESD 2056
            + +         W  V ++ D +     I  L     Y  R+ A N  G   +SEP E  
Sbjct: 1002 WTVQGLIGQSDRWETVFELSDSSARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSEQI 1061

Query: 2057 EPFKVIP 2063
            +  + +P
Sbjct: 1062 QTDQDVP 1068



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 7/218 (3%)

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
            TY F + A    G   P ++    T  +T   P  P    V    SR V L WT P +NG
Sbjct: 1336 TYYFEVTASTLTGFGQPASALVITTTDRTA--PEAPSKPTVDHIKSRQVRLSWT-PGNNG 1392

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
             SP+  YII+ +   G      +TV  S   + +  +       FR+   N +G S P  
Sbjct: 1393 NSPLRYYIIDVRVDSGPWAQHSMTVDASQVSYIVTGLNPHTLYYFRLKVYNDIGAS-PES 1451

Query: 1954 SQSVRLEKHATVP-SPPTAPLEIRMVGSNIVMTSWGTP-EWDGGAPLLGYNIAIRDVTKT 2011
              S +      +P   PT      +  +++++T W  P +     PL GY+   R +   
Sbjct: 1452 PTSDQTTTEQDIPEGVPTITGATPITVTSLLVT-WQPPLQAQTNGPLTGYSFQFRQLPGG 1510

Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
             +ME    D    +  + +L     Y +++ A N IGL
Sbjct: 1511 SFMEETISDAGVTEHELLNLVRYQNYEVKLAATNSIGL 1548



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 74/313 (23%), Positives = 123/313 (39%), Gaps = 25/313 (7%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS++   C   G P PQI W+R  A I    + +   +DD   +L +  +   D+G F C
Sbjct: 360 GSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDD--GSLKLSNIEKADSGMFQC 417

Query: 584 VAKNAAGFASSTT-----ELIVEAPLSDHGS-----EMTVXXXXXXXXXXXXADILEGIP 633
            A N  G     T     E+  E  L+ + +     E T                 + I 
Sbjct: 418 QAINDVGEQIVDTWLQVQEIAPEITLAPNDTTILEGETTYLECAAEGAPHPTIHWEKEIA 477

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P  +  P    + EG    LEC     P P I W  K  ++V   +  +     +  + +
Sbjct: 478 PEITLSPNDTTILEGETTYLECAAEGAPHPTIHW-EKDGQLVLSASFRLNDRYVLQTFGN 536

Query: 694 VLKITNVKKFQEGTYTVVAVN--REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
           +L    VK+   G YT +A N      +S  +++  +T   + P  ++ +       GE+
Sbjct: 537 LLLQQAVKE-DSGEYTCIATNTLNTANSSASLIVYQRTVISQKPTSVQTI------LGET 589

Query: 752 VILSAQVVGNPR--PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
             L+  V  + R  PT+TW ++   +         ++ S+ IL      D G+Y  K  +
Sbjct: 590 TTLNCVVQHDSRVTPTVTWMQDGGVIIPNGRFIIQESGSLVILS-TDANDMGLYVCKVTS 648

Query: 810 SEGIAETSAVITV 822
             G    SA +TV
Sbjct: 649 IAGDDLGSANLTV 661



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 10/140 (7%)

Query: 637 SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           +K P  + + E  GS I L C    +P P I W     +I    N    +E D       
Sbjct: 347 NKSPLERIIQEAAGSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDD-----GS 401

Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
           LK++N++K   G +   A+N  GE  +   L+++  E  P   + P  + I+ +GE+  L
Sbjct: 402 LKLSNIEKADSGMFQCQAINDVGEQIVDTWLQVQ--EIAPEITLAPNDTTIL-EGETTYL 458

Query: 755 SAQVVGNPRPTITWCKNNKP 774
                G P PTI W K   P
Sbjct: 459 ECAAEGAPHPTIHWEKEIAP 478



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 14/198 (7%)

Query: 731 EKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----D 785
           EKE  P++        + +GE+  L     G P PTI W K+ + V +   + +      
Sbjct: 473 EKEIAPEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQ 532

Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
           T    +L+    +D G YT  A N+   A +SA + V + T  + +P       Q I + 
Sbjct: 533 TFGNLLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVISQKP----TSVQTI-LG 587

Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905
           E  T+  V +      P++TW ++  +I P+        G    LVI + D+  D G Y 
Sbjct: 588 ETTTLNCVVQHDSRVTPTVTWMQDGGVIIPNGRFIIQESG---SLVILSTDAN-DMGLYV 643

Query: 906 CVASNSAGKSSHGARVTI 923
           C  ++ AG     A +T+
Sbjct: 644 CKVTSIAGDDLGSANLTV 661



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 7/100 (7%)

Query: 505 EQSMAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--Y 560
           E+ +AP     L P  T   +G T   EC  EG P P I W +   ++  S  F++   Y
Sbjct: 473 EKEIAPEIT--LSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVL-SASFRLNDRY 529

Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
                  L++++   ED+G +TC+A N    A+S+  LIV
Sbjct: 530 VLQTFGNLLLQQAVKEDSGEYTCIATNTLNTANSSASLIV 569



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 1375 VTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VK 1431
            +T  D+ +P  P KP +  I S  + + W  P N GNS + YY+++ + +D+  W     
Sbjct: 1358 ITTTDRTAPEAPSKPTVDHIKSRQVRLSW-TPGNNGNSPLRYYIIDVR-VDSGPWAQHSM 1415

Query: 1432 NITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
             +  +Q S  +  L  ++ Y FR    N++  S  S T++     ++     PT+
Sbjct: 1416 TVDASQVSYIVTGLNPHTLYYFRLKVYNDIGASPESPTSDQTTTEQDIPEGVPTI 1470



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 7/129 (5%)

Query: 1485 EKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXX 1540
            + PL+ I  E     I L C+  GVP P++ WYR+   + T   ++   E+         
Sbjct: 348  KSPLERIIQEAAGSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDDGSLKLSNI 407

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                   ++C A ND GE      + +Q+  P IT++  D       G+   +    EG 
Sbjct: 408  EKADSGMFQCQAINDVGEQIVDTWLQVQEIAPEITLAPNDTTILE--GETTYLECAAEGA 465

Query: 1600 PPPEVIWYK 1608
            P P + W K
Sbjct: 466  PHPTIHWEK 474



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITNVDSEI 899
           + T+ E  T  L       P P+I W ++ +++ S S  +   +  +    ++     + 
Sbjct: 486 DTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQTFGNLLLQQAVKE 545

Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
           DSG+Y C+A+N+   ++  A  ++ V + T +     S +T  G+T  L C   H
Sbjct: 546 DSGEYTCIATNTLNTANSSA--SLIVYQRTVISQKPTSVQTILGETTTLNCVVQH 598



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 7/103 (6%)

Query: 1374 NVTILDKPSPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
            N+T   +   P  P  ++    SS + + W+E    G++ +I Y+++ QE     W +V 
Sbjct: 1760 NITTGPQEGAPDSPTNIDXSPGSSFLTVSWEELVFHGDNPLIGYIIQSQEKGQDTWENVN 1819

Query: 1432 N---ITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            +     ++Q SI   +L   + Y FR  A +E+ +S+ + + E
Sbjct: 1820 DTIGANQSQFSIPYSSLDPVTVYTFRVMAESEISVSEPAPSEE 1862



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 43/198 (21%), Positives = 74/198 (37%), Gaps = 23/198 (11%)

Query: 997  IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEI 1055
            ++C  +     T+   KE  PE      D  + E +   LE          + WE+DG++
Sbjct: 458  LECAAEGAPHPTIHWEKEIAPEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQL 517

Query: 1056 IKPKK----NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---------EVTV 1102
            +        ++Y  +  G+   L ++     D GEY+CI  +   TA         + TV
Sbjct: 518  VLSASFRLNDRYVLQTFGN---LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTV 574

Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
            +   P  +  +  +          +  +T     V W +DG  I  +    +   G    
Sbjct: 575  ISQKPTSVQTILGETTTLNCVVQHDSRVT---PTVTWMQDGGVIIPNGRFIIQESG---S 628

Query: 1163 LKIYDCDLDDAGEYSCEV 1180
            L I   D +D G Y C+V
Sbjct: 629  LVILSTDANDMGLYVCKV 646



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 6/121 (4%)

Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
           +I L    T  P P I WYRN   I+         + +   L ++N++ + DSG ++C A
Sbjct: 362 SITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDDG-SLKLSNIE-KADSGMFQCQA 419

Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYET-EEGKTVILECQTSHTVSTKWYHNKKEI 967
            N  G+        + V+++     L  +  T  EG+T  LEC  +        H +KEI
Sbjct: 420 INDVGEQI--VDTWLQVQEIAPEITLAPNDTTILEGETTYLEC-AAEGAPHPTIHWEKEI 476

Query: 968 S 968
           +
Sbjct: 477 A 477


>UniRef50_UPI0000DB7210 Cluster: PREDICTED: similar to Stretchin-Mlck
            CG18255-PA, isoform A; n=1; Apis mellifera|Rep:
            PREDICTED: similar to Stretchin-Mlck CG18255-PA, isoform
            A - Apis mellifera
          Length = 2577

 Score =  104 bits (250), Expect = 2e-20
 Identities = 144/614 (23%), Positives = 255/614 (41%), Gaps = 67/614 (10%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            EG PP F ++     V  G+       + +   P I W    E+I      S   E   +
Sbjct: 112  EGDPPIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEG--N 169

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748
             YC  + +  V    EG +T +A NR G +S    L +   +  + P+ +E L++++   
Sbjct: 170  FYC--VDVAPVTVEDEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPEFVEELRALLTET 227

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
            G +V L  +VVG P P + W K+NK +KA      GD  ++T          G+YT +A 
Sbjct: 228  G-TVSLECKVVGVPTPVLRWFKDNKEIKA------GDVFALT-ANLDDPTSLGIYTCEAV 279

Query: 809  NSEGIAETSAVITV--EEPTEENAEP----------PLFINRFQEITVKEKGTIKLVARV 856
            N  GIA +S+ + V  +   E + +P          P+F    Q+   +   T++L  +V
Sbjct: 280  NCMGIAYSSSKVHVVGKGSREGSLKPADSLIPFGPLPIFTKILQDECCRIGDTLRLSCQV 339

Query: 857  TRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-K 914
               P P +ITWY     I  SE      DG     +  N    +D G++KCVA+N+   K
Sbjct: 340  QVPPWPKAITWYNKEGRIEASEKYHVMEDGLGGYSIEVNPVEAMDEGEWKCVATNAEDMK 399

Query: 915  SSHGARVTIDV----EKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEIS 968
                  V + +     K  F++ L K+  TEEG  V  EC+     T   +W+ + +E+ 
Sbjct: 400  QFTTCHVAMSIPKNYRKPRFMESL-KAVLTEEG-LVSFECKVVGFPTPLLRWFKDGQELK 457

Query: 969  GMDHREIIQE---------GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019
              D  ++             R             +  I+  + ++E   +L   +  P F
Sbjct: 458  PGDVYQLTGTNSLGSYCCIARNCMGEAKSTAELTIEDIQNQLNEEERLQLLNTNQP-PIF 516

Query: 1020 IRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
            I+ L+  E +  +     V+++ S      W RD   ++  +     ++   I  L ++ 
Sbjct: 517  IKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQK 576

Query: 1079 TSVHDEGEYSCILRDE------SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIE- 1129
                D+ E+ C+  ++      SC  ++ + +    P+ +  L+    ++G     E + 
Sbjct: 577  LEFVDQAEWKCVASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEG-AVNLECKV 635

Query: 1130 LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189
            +     +++W+KDG E++    I   I G+        C L   G Y+CE  N  C   +
Sbjct: 636  IGVPQPILKWYKDGVELK-PGDIHRIISGQDG-----TCCL---GTYTCEATN--CMGTV 684

Query: 1190 TVEEPSINFTLRLP 1203
            +     + F  +LP
Sbjct: 685  SSSASLLGFEDKLP 698



 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 153/659 (23%), Positives = 273/659 (41%), Gaps = 81/659 (12%)

Query: 729  TGEKEPPQVIEPLKSMIV--RQGESVILSAQVVGNP---RPTITWCKNNKPVKA--LPTK 781
            T  K PP+ ++P +++ V  R GE +++  ++  +           + + P+ +     +
Sbjct: 2    TKVKGPPRWLDPDQALPVQGRVGEDIVIEPRLRWSDVFDELRFELIRGDVPIPSDRYRVQ 61

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAEN-SEGIAETSAV---ITVEEPTEENAEPPLFIN 837
              G+   +T LK  +  D G Y L A    +G  + S+    ++V+E   E  +PP+F+ 
Sbjct: 62   MRGNVVQLT-LKQSQKDDTGHYALVATRVGQGFEKGSSKKIHLSVDEAISEEGDPPIFLR 120

Query: 838  RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
            R  ++ VK     + +  +  +  P ITW+RN E I      +   +G    + +  V  
Sbjct: 121  RLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEGNFYCVDVAPVTV 180

Query: 898  EIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYETEEGKTVILECQT- 952
            E D G + C+A N  G+SS  +R+T+ V K      FV+ L ++  TE G TV LEC+  
Sbjct: 181  E-DEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPEFVEEL-RALLTETG-TVSLECKVV 237

Query: 953  -SHTVSTKWYHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGV------IKCIVKD 1003
               T   +W+ + KEI   D   +    +               +G+      +  + K 
Sbjct: 238  GVPTPVLRWFKDNKEIKAGDVFALTANLDDPTSLGIYTCEAVNCMGIAYSSSKVHVVGKG 297

Query: 1004 QETSTM-----LVVKETIPEFIRKLQDFEVKEKDVAIL--EVEINSETADVVW-ERDGEI 1055
                ++     L+    +P F + LQD   +  D   L  +V++      + W  ++G I
Sbjct: 298  SREGSLKPADSLIPFGPLPIFTKILQDECCRIGDTLRLSCQVQVPPWPKAITWYNKEGRI 357

Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115
               +K     +  G    + +      DEGE+ C+  +     + T   +   I    + 
Sbjct: 358  EASEKYHVMEDGLGGY-SIEVNPVEAMDEGEWKCVATNAEDMKQFTTCHVAMSIPKNYRK 416

Query: 1116 QKVNKGNKA--------TFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166
             +  +  KA        +FE ++      L+RWFKDG E++  +  QLT       L  Y
Sbjct: 417  PRFMESLKAVLTEEGLVSFECKVVGFPTPLLRWFKDGQELKPGDVYQLT---GTNSLGSY 473

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVE--EPSINFTLRL--------PEFIL------VPA 1210
             C   +       +G +K TA LT+E  +  +N   RL        P FI          
Sbjct: 474  CCIARNC------MGEAKSTAELTIEDIQNQLNEEERLQLLNTNQPPIFIKGLRSCEARI 527

Query: 1211 NTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTC 1268
            N D   TV++        +WY+  + +E+ E++ +  + +    L ++K    DQ E+ C
Sbjct: 528  NEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKC 587

Query: 1269 VLLD--AKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            V  +   +S T   LK+ + +    PK ++  R      G+ V L       PQP  +W
Sbjct: 588  VASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEGA-VNLECKVIGVPQPILKW 645



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 102/431 (23%), Positives = 178/431 (41%), Gaps = 59/431 (13%)

Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
           E+   PIF+ +L       G+  +F  ++     P+ITW R    I     F   ++  N
Sbjct: 111 EEGDPPIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEG-N 169

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              + +  V  ED G +TC+A+N  G +S T+ L V  P +    E              
Sbjct: 170 FYCVDVAPVTVEDEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPE-------------- 215

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
                      F ++ +A   + G+ + LEC++V +P P + W    +EI   +  ++  
Sbjct: 216 -----------FVEELRALLTETGT-VSLECKVVGVPTPVLRWFKDNKEIKAGDVFALTA 263

Query: 685 ESD----MHMY-CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE 739
             D    + +Y C  +    +       + V   +REG    P    I  G    P   +
Sbjct: 264 NLDDPTSLGIYTCEAVNCMGIAYSSSKVHVVGKGSREGSLK-PADSLIPFGPL--PIFTK 320

Query: 740 PLKSMIVRQGESVILSAQVVGNPRP-TITWCKNNKPVKA---LPTKSDG-DTHSITILKP 794
            L+    R G+++ LS QV   P P  ITW      ++A        DG   +SI +  P
Sbjct: 321 ILQDECCRIGDTLRLSCQVQVPPWPKAITWYNKEGRIEASEKYHVMEDGLGGYSIEV-NP 379

Query: 795 KKVKDEGVYTLKAENSEGIAE-TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
            +  DEG +   A N+E + + T+  + +  P  +N   P F+   + + + E+G +   
Sbjct: 380 VEAMDEGEWKCVATNAEDMKQFTTCHVAMSIP--KNYRKPRFMESLKAV-LTEEGLVSFE 436

Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            +V   P P + W+++ + + P         G+  +L  TN       G Y C+A N  G
Sbjct: 437 CKVVGFPTPLLRWFKDGQELKP---------GDVYQLTGTN-----SLGSYCCIARNCMG 482

Query: 914 KSSHGARVTID 924
           ++   A +TI+
Sbjct: 483 EAKSTAELTIE 493



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 70/308 (22%), Positives = 133/308 (43%), Gaps = 24/308 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F +  KA   +EG  +  EC++V  P P + W   G+E+ P +   +   + +  YC 
Sbjct: 417 PRFMESLKAVLTEEGL-VSFECKVVGFPTPLLRWFKDGQELKPGDVYQLTGTNSLGSYCC 475

Query: 694 VLK--ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
           + +  +   K   E T   +      E  L ++        +PP  I+ L+S   R  E 
Sbjct: 476 IARNCMGEAKSTAELTIEDIQNQLNEEERLQLL-----NTNQPPIFIKGLRSCEARINED 530

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSITILKPKKVK--DEGVYTLKAE 808
              + QV  +P P+ +W +++ PV+     +   +   I  L  +K++  D+  +   A 
Sbjct: 531 FRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKCVAS 590

Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
           N  G + TS  + +  P  ++ + P F+   + I + ++G + L  +V   P P + WY+
Sbjct: 591 NDHGQSITSCFLKLIIP--KHYKKPKFLESLRAI-LSDEGAVNLECKVIGVPQPILKWYK 647

Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
           +   + P +          I  +I+  D     G Y C A+N  G  S  A +    +K+
Sbjct: 648 DGVELKPGD----------IHRIISGQDGTCCLGTYTCEATNCMGTVSSSASLLGFEDKL 697

Query: 929 TFVKHLQK 936
              K +++
Sbjct: 698 PVRKEIKE 705



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 121/546 (22%), Positives = 222/546 (40%), Gaps = 47/546 (8%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+R+L D  VK        VEI S T   + W R+ E I     ++ F   G+   + 
Sbjct: 116  PIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAG-TRFSFVHEGNFYCVD 174

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP-----PEIITRLQNQKVNKGNKATF 1126
            +   +V DEG ++C+  +     SCT+ +TV+ +P     PE +  L+      G  +  
Sbjct: 175  VAPVTVEDEGHWTCMAENRGGRSSCTSRLTVI-VPKAYKRPEFVEELRALLTETGTVSLE 233

Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTID-GKKQKLKIYDCD-LDDAG-EYSCE---- 1179
               +     ++RWFKD  EI+  +   LT +      L IY C+ ++  G  YS      
Sbjct: 234  CKVVGVPTPVLRWFKDNKEIKAGDVFALTANLDDPTSLGIYTCEAVNCMGIAYSSSKVHV 293

Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--------TVEIPDETLDVTWYK 1231
            VG       L   +  I F   LP F  +  +    +         V++P     +TWY 
Sbjct: 294  VGKGSREGSLKPADSLIPFG-PLPIFTKILQDECCRIGDTLRLSCQVQVPPWPKAITWYN 352

Query: 1232 KKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP- 1287
            K+  IE +EK+ ++ D +   ++ +      D+ E+ CV  +A+   +       +  P 
Sbjct: 353  KEGRIEASEKYHVMEDGLGGYSIEVNPVEAMDEGEWKCVATNAEDMKQFTTCHVAMSIPK 412

Query: 1288 ----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKS 1342
                P+ ++  +    + G  V+       FP P   W  + + +K    +     +S  
Sbjct: 413  NYRKPRFMESLKAVLTEEGL-VSFECKVVGFPTPLLRWFKDGQELKPGDVYQLTGTNSLG 471

Query: 1343 ASLTIKKVENTDA-GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            +   I +    +A    +L +E+     + E  + +L+   PP     L    + IN  +
Sbjct: 472  SYCCIARNCMGEAKSTAELTIEDIQNQLNEEERLQLLNTNQPPIFIKGLRSCEARINEDF 531

Query: 1402 DEPENTGNS---TIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
                    S   +  +Y  +    +   + ++ +N+      +Q L+      ++  A N
Sbjct: 532  RFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKCVASN 591

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
            +      S T+ + K+I     + P   + L+ I ++    + L C   GVPQP + WY+
Sbjct: 592  D---HGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYK 647

Query: 1518 DGKKLK 1523
            DG +LK
Sbjct: 648  DGVELK 653



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 54/227 (23%), Positives = 90/227 (39%), Gaps = 18/227 (7%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYENRX--X 1534
            Q P   K L++     NED   T      P+P  +WYRD    ++ +  +   EN     
Sbjct: 512  QPPIFIKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICH 571

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQKHKVGDE 1589
                         +KC+A NDHG+  TSC + +      +KP    S   I     + DE
Sbjct: 572  LDVQKLEFVDQAEWKCVASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAI-----LSDE 626

Query: 1590 WLVT--AVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
              V     + G+P P + WYK+G +L+  D    I+ ++ T  +     + ++       
Sbjct: 627  GAVNLECKVIGVPQPILKWYKDGVELKPGDIHRIISGQDGTCCLGTYTCEATNCMGTVSS 686

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
            +++  G        K   +P  P G  + R +S  ++  E    L D
Sbjct: 687  SASLLGFEDKLPVRKEIKEPQSPNGHELARNLSLSTIHEERTSQLYD 733



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 37/169 (21%), Positives = 73/169 (43%), Gaps = 26/169 (15%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           PIF++ LR          +F  QV   P P  +W+R    ++ ++ +++  ++  +  L 
Sbjct: 514 PIFIKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLD 573

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
           ++++   D   + CVA N  G   S T   ++  +  H  +                   
Sbjct: 574 VQKLEFVDQAEWKCVASNDHG--QSITSCFLKLIIPKHYKK------------------- 612

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
               P F +  +A   DEG+ + LEC+++ +P+P + W   G E+ P +
Sbjct: 613 ----PKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYKDGVELKPGD 656



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 11/90 (12%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+E LR   + +G+ V  EC+V G P+P + W++    +KP    ++    D    L 
Sbjct: 613 PKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYKDGVELKPGDIHRIISGQDGTCCL- 670

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELI 599
                    GT+TC A N  G  SS+  L+
Sbjct: 671 ---------GTYTCEATNCMGTVSSSASLL 691


>UniRef50_Q4S0Y7 Cluster: Chromosome 5 SCAF14773, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5
            SCAF14773, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 931

 Score =  104 bits (249), Expect = 3e-20
 Identities = 76/294 (25%), Positives = 125/294 (42%), Gaps = 11/294 (3%)

Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732
            VI    +  SV I+W PP +   L    Y I++    +  W+       +   + +  L 
Sbjct: 115  VIATRETDTSVLIQWAPPKEPNNL--IGYYIDQCVKGSKDWMSANHKPHNSTKFVVSGLT 172

Query: 1733 ENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
            +   Y+FRV A N +G SE + ES PI +K AL  PS           D  S+ +TW   
Sbjct: 173  KGETYVFRVQAINELGLSEESQESAPITVKAALTPPSAPYDISLLS-CDGHSMLLTWKKP 231

Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
              +GGS I +Y V+ ++ G   W+            +++ L+    YQF++YA N  G  
Sbjct: 232  LLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQVYAANLAGLG 291

Query: 1849 -LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907
                 SDD    G T+  P    +  ++E    S+ ++W +P   G  P+T Y +E+   
Sbjct: 292  PASKHSDDFACEGWTMPEPGPAYDLSLTEVRDHSMVVEWKKPVYTGSGPVTGYHVEYCKT 351

Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG---VSLPTESQSVR 1958
                WT             +  ++E     FR+   N  G   VS+P++  + +
Sbjct: 352  GTSEWTTATETAVHQRFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAK 405



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 70/305 (22%), Positives = 123/305 (40%), Gaps = 6/305 (1%)

Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808
            F   +  E + +++ LD               + SV I W P ++     +I Y ++   
Sbjct: 90   FCLPISMETVSLQSRLDPSRLRSSKVIATRETDTSVLIQWAPPKEPNN--LIGYYIDQCV 147

Query: 1809 EGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865
            +G K W           +  +  L+   TY FR+ A NE+G S        IT+   LTP
Sbjct: 148  KGSKDWMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQESAPITVKAALTP 207

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            PS P +  +      S+ L W +P  +GGS I  Y ++ +      W ++     S   +
Sbjct: 208  PSAPYDISLLSCDGHSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVY 267

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNIVM 1984
             +E + E     F++ A N  G+   ++       +  T+P P P   L +  V  + ++
Sbjct: 268  KVEGLTEGAVYQFQVYAANLAGLGPASKHSDDFACEGWTMPEPGPAYDLSLTEVRDHSMV 327

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              W  P + G  P+ GY++       + W    +  V+   F +  L E   Y  R+   
Sbjct: 328  VEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQRFFKVTGLEEGVNYEFRVRGV 387

Query: 2045 NEIGL 2049
            N+ G+
Sbjct: 388  NDAGV 392



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 74/350 (21%), Positives = 133/350 (38%), Gaps = 18/350 (5%)

Query: 1606 WYKNGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            W    +K  N  ++ ++  TK +T V R++ +     S+ + E        S  +T+K  
Sbjct: 153  WMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQE--------SAPITVKAA 204

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
              P      + +      S+ + WK PL  GG  + +Y ++K       W +V       
Sbjct: 205  LTPPSAPYDISLLSCDGHSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISE 264

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS-XXXXXXXXXXIDNE 1782
              Y ++ L E   Y F+V A N  G   A +           +P            + + 
Sbjct: 265  RVYKVEGLTEGAVYQFQVYAANLAGLGPASKHSDDFACEGWTMPEPGPAYDLSLTEVRDH 324

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXA--RIQKLSINTTYQFRI 1839
            S+ + W      G  P+  Y VE  + G  +W             ++  L     Y+FR+
Sbjct: 325  SMVVEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQRFFKVTGLEEGVNYEFRV 384

Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
               N+ G  +     D +T  K L   SQ  +  V + T   + L +     N  S    
Sbjct: 385  RGVNDAGVGMVSMPSDPMT-AKALA-GSQEVSCTVDKKTG-DIVLSFESCVMNQESQFI- 440

Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
            +  ++K +   S   +V   G+  +   +N +++D  ++ +S  NT GVS
Sbjct: 441  WKKDYKEITDFSKGVVVKTEGNTSKLIFKNAEKEDFGVYSVSVTNTDGVS 490



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 48/199 (24%), Positives = 92/199 (46%), Gaps = 10/199 (5%)

Query: 1866 PSQPRN--FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSV 1922
            PS+ R+   + +  T  SV ++W  P+      +  Y I+ + VKG K W        + 
Sbjct: 107  PSRLRSSKVIATRETDTSVLIQWAPPKEPNN--LIGYYID-QCVKGSKDWMSANHKPHNS 163

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG--S 1980
             +  +  + + +  +FR+ A N +G+S  ++  +    K A   +PP+AP +I ++    
Sbjct: 164  TKFVVSGLTKGETYVFRVQAINELGLSEESQESAPITVKAAL--TPPSAPYDISLLSCDG 221

Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            + ++ +W  P   GG+ +  Y +  R    TMW EV    ++   + +  L+E   Y  +
Sbjct: 222  HSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQ 281

Query: 2041 IYARNEIGLSEPLESDEPF 2059
            +YA N  GL    +  + F
Sbjct: 282  VYAANLAGLGPASKHSDDF 300



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 40/184 (21%), Positives = 82/184 (44%), Gaps = 19/184 (10%)

Query: 1301 RGSDVTLLVDYQAFPQPN-------DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
            R +D ++L+ +    +PN       D+ +  SK      H KP     S    +  +   
Sbjct: 119  RETDTSVLIQWAPPKEPNNLIGYYIDQCVKGSKDWMSANH-KPH---NSTKFVVSGLTKG 174

Query: 1354 DAGIYKLRLENNCGHADVEMN---VTILDKPSPPGKP---NILEIDSSSINICWDEPENT 1407
            +  +++++  N  G ++       +T+    +PP  P   ++L  D  S+ + W +P  +
Sbjct: 175  ETYVFRVQAINELGLSEESQESAPITVKAALTPPSAPYDISLLSCDGHSMLLTWKKPLLS 234

Query: 1408 GNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
            G S I  Y V+ +   TT W  + +  I++    ++ L   + Y+F+ YA N   +  AS
Sbjct: 235  GGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQVYAANLAGLGPAS 294

Query: 1466 ETTE 1469
            + ++
Sbjct: 295  KHSD 298



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 6/122 (4%)

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            IS+E  + +S+ T S   RL+      S   A  E        V+  W  P+      L+
Sbjct: 86   ISSEFCLPISMETVSLQSRLDPSRLRSSKVIATRET----DTSVLIQWAPPKEPNN--LI 139

Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059
            GY I         WM       N+ KF +  L++  TY+ R+ A NE+GLSE  +   P 
Sbjct: 140  GYYIDQCVKGSKDWMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQESAPI 199

Query: 2060 KV 2061
             V
Sbjct: 200  TV 201



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            + +P P    ++ E+   S+ + W +P  TG+  +  Y VEY +  T+EW +       Q
Sbjct: 307  MPEPGPAYDLSLTEVRDHSMVVEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQ 366

Query: 1438 T--SIQNLKTNSSYRFRAYAVNEVDISDASETTE--YYKVIKETKIQSPTVEKPLKNI 1491
                +  L+   +Y FR   VN+  +   S  ++    K +  ++  S TV+K   +I
Sbjct: 367  RFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAKALAGSQEVSCTVDKKTGDI 424



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 52/253 (20%), Positives = 109/253 (43%), Gaps = 29/253 (11%)

Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL-----PIVLKIKTGEKEPP 735
           + A E+ +H      K+T +++     + V  VN  G   +     P+  K   G +E  
Sbjct: 357 TTATETAVHQ--RFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAKALAGSQEVS 414

Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITI 791
             ++     IV   ES ++      N      W K+ K +    K +  K++G+T  + I
Sbjct: 415 CTVDKKTGDIVLSFESCVM------NQESQFIWKKDYKEITDFSKGVVVKTEGNTSKL-I 467

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA------EPPLFINRFQEITVK 845
            K  + +D GVY++   N++G++ +  + + EE T+  A       P + +       + 
Sbjct: 468 FKNAEKEDFGVYSVSVTNTDGVSSSYGIYS-EEMTKMLALSYDIRHPIIPLKAELAYKIL 526

Query: 846 EKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGEN--IELVITNVDSEIDSG 902
           E+G ++   +    +P  +  ++ NN+ +S ++      D     IE ++ +   E + G
Sbjct: 527 ERGRVRFWLQAEEISPNVTYKFFANNKELSGADPNKMGHDVSTGIIEFILDHFTEE-NEG 585

Query: 903 DYKCVASNSAGKS 915
            + C  ++  GK+
Sbjct: 586 TFTCQITDGGGKA 598



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 32/155 (20%), Positives = 63/155 (40%), Gaps = 11/155 (7%)

Query: 527 VQFECQVEGYPRPQ-ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           +Q +C ++ Y     ITW+     +  S  F++     ++AT+ + E   +D GT++ V 
Sbjct: 741 IQLQCHMKYYTSEMNITWYHGETKLLHSDKFKIG-GTPSMATMEVIEPTEKDQGTYSIVI 799

Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645
            +       T  L  E     H   + +              ++ G+P   +       +
Sbjct: 800 VDPENSHKRTLNLSGEVYEKAHAEFLQLNLHVCVCLDR--GKVVGGLPDVVT-------I 850

Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680
            E   + L C +   P+P ++WL  G E+ PD+ +
Sbjct: 851 MEKKTLSLTCTVCGDPKPQVSWLKSGAEVEPDDKV 885


>UniRef50_A6NI63 Cluster: Uncharacterized protein MYOM3; n=42;
            Tetrapoda|Rep: Uncharacterized protein MYOM3 - Homo
            sapiens (Human)
          Length = 1441

 Score =  104 bits (249), Expect = 3e-20
 Identities = 131/533 (24%), Positives = 218/533 (40%), Gaps = 73/533 (13%)

Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLE----NDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            L+T  ++  PPP+V WYKN  +++       +Y IT       + I+      S+ YT+ 
Sbjct: 172  LLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVR 231

Query: 1647 ASNTAGTSS--VEVTLKVY-DKPSKPEGPVIMREISRESV--TIEWKPPL--DDGGLELT 1699
              N  G +S   +V ++ Y  K +  +  +  R     SV  T   KP    +     L+
Sbjct: 232  VKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLS 291

Query: 1700 -KYAIEKHEPDNNRWI------------KVADVDRD--VETYCIQKLNENCEYMFRVIAQ 1744
              ++ +  + ++ +W             K+   DR   ++  C  K +E   YM RV   
Sbjct: 292  CLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGL-YMVRV--- 347

Query: 1745 NPVGFSEALESEPIVIKTA-LDVPSXXXXXXXXXXID--NESVYITWFPSEKNGGSPIID 1801
             P  F    +S  ++++ A  + P           +D   + + +TW P     G+PI  
Sbjct: 348  -PSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITA 406

Query: 1802 YKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTS---------- 1848
            Y +E  Q E  +W           R  IQ L    +Y+FR+ A + +G+S          
Sbjct: 407  YTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVV 466

Query: 1849 ------------LPYTSDDKITIGK-----TLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891
                        +P+   +KITI       T+T PS P N   SE     V L W EP  
Sbjct: 467  MGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSP 526

Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
               +P+T Y +E   +   +W  I +          + ++++K   +FR+ A N  G+S 
Sbjct: 527  RDRAPLT-YSLEKSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSD 585

Query: 1951 PTE-SQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
            P+E S+ + L    AT+P PP      R   +++ +T W  P  D    LLGY I  R V
Sbjct: 586  PSEPSEPIALRGPPATLP-PPAQVQAFRDTQTSVSLT-W-DPVKD--PELLGYYIYSRKV 640

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
              + W  V    +   +F +  L     Y   + + +E G+ E   + EP +V
Sbjct: 641  GTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRV 693



 Score = 83.8 bits (198), Expect = 5e-14
 Identities = 80/332 (24%), Positives = 130/332 (39%), Gaps = 16/332 (4%)

Query: 1632 IKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            + +L++  S  + + A N  G S     S  + L+       P   V     ++ SV++ 
Sbjct: 562  VLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLT 621

Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            W P  D    EL  Y I   +   + W  V +       + +  L    EY F V + + 
Sbjct: 622  WDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSE 678

Query: 1747 VGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805
             G  E+   +EPI +K AL  PS            NE V I W P ++ GG  I+ Y ++
Sbjct: 679  AGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMV-IGWKPPKRRGGGKILGYFLD 737

Query: 1806 IKQ-EGKKWKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK- 1861
                E   W             ++  L     Y+FR  A N  G              + 
Sbjct: 738  QHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEW 797

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921
            T+  P  P +   SE  + S+ L+W  P   G  P+T Y + F+    + W K VT G  
Sbjct: 798  TMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQW-KPVTPGPI 856

Query: 1922 VHEHC-IENIKEKDEIIFRISAENTVGVSLPT 1952
               H  + +++     +F++ A N+ G+  P+
Sbjct: 857  SGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPS 888



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 56/222 (25%), Positives = 93/222 (41%), Gaps = 11/222 (4%)

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIG---KTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
            +Y FR+ A N+ G S P    + I +     TL PP+Q + F     T  SV+L W +P 
Sbjct: 570  SYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAF---RDTQTSVSLTW-DPV 625

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
             +    +  Y I  + V    W  +           +  ++   E  F + + +  GV  
Sbjct: 626  KD--PELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGE 683

Query: 1951 PTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009
             + + + +R+++    PS P     +   G N ++  W  P+  GG  +LGY +   D  
Sbjct: 684  SSAATEPIRVKQALATPSAPYG-FALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSE 742

Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            +  W  V +  + T    + DL E H Y  R  A N  G+ E
Sbjct: 743  ELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGE 784



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 63/279 (22%), Positives = 116/279 (41%), Gaps = 36/279 (12%)

Query: 1227 VTWYKKKSVIED----TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLK 1280
            VTWYK  + I+       K+ + ++    +L IR+C  +D   YT  + +A  ++++  K
Sbjct: 185  VTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAK 244

Query: 1281 VEVVEFPPKIVDYEREY---------------------RIKRGSDVTLLVDYQAFPQPND 1319
            V V  +  K   ++ E                      R K    ++ L         + 
Sbjct: 245  VLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLSCLFSEDVLDAESI 304

Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            +W  +  +++  +  K     + ASL +      D G+Y +R+ +  G  +    V + D
Sbjct: 305  QWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRD 364

Query: 1380 ----KPSPPGKP-NI--LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
                 P  PG P N+  L+++   + + W  P +T  + I  Y +E  + ++ EWI+   
Sbjct: 365  AEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE 424

Query: 1433 IT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                  +  IQ L    SYRFR  A++ V  S  S+ +E
Sbjct: 425  APGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASE 463



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 48/215 (22%), Positives = 81/215 (37%), Gaps = 6/215 (2%)

Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
            ++A T  + V  +    PS P G  ++    +  + I WKPP   GG ++  Y +++H+ 
Sbjct: 684  SSAATEPIRVK-QALATPSAPYGFALLN-CGKNEMVIGWKPPKRRGGGKILGYFLDQHDS 741

Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768
            +   W  V           +  L+E   Y FR  A N  G  E      +       +P 
Sbjct: 742  EELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQ 801

Query: 1769 -XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK--XXXXXXXXXA 1824
                       +   S+ + W P    G  P+  Y V  ++EG ++WK            
Sbjct: 802  PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHL 861

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859
            R+  L    +Y F++ A N  G   P    D + +
Sbjct: 862  RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLL 896



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 3/98 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN---VA 566
           P F   LR     + +TV   C V+  P PQ+TW++    I P       Y   N   + 
Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
           +L IR    ED+ T+T   KNA G ASS  +++V   L
Sbjct: 214 SLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYL 251



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 30/141 (21%), Positives = 67/141 (47%), Gaps = 11/141 (7%)

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMN---VTILDKPS---PPGKPNILEIDS 1394
            +S    +  +E   + ++++R  N  G +D       + +   P+   PP +        
Sbjct: 556  RSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQ 615

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452
            +S+++ WD  ++     ++ Y +  +++ T+EW +V N  I  T+ ++  L+T   Y F 
Sbjct: 616  TSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFC 672

Query: 1453 AYAVNEVDISDASETTEYYKV 1473
              +V+E  + ++S  TE  +V
Sbjct: 673  VRSVSEAGVGESSAATEPIRV 693



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 21/205 (10%)

Query: 740  PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796
            PLK     +G  +    +         TW   +K +++   + T +  D   + IL PK 
Sbjct: 1230 PLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKD 1289

Query: 797  VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE----PPLFI---NRFQEI------- 842
              D+G YTL+    + + + S  ++ +   +  AE      L I   NR + +       
Sbjct: 1290 -SDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVA 1348

Query: 843  TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902
            T+ E  T+ L   V+ +P P I+W +N++ ++  +       G  + + I  V+SE DSG
Sbjct: 1349 TIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSE-DSG 1407

Query: 903  DYKCVASNSAGKSSHGARVTIDVEK 927
             Y     N  G  S   +VTI V K
Sbjct: 1408 RYGVFVKNKYG--SETGQVTISVFK 1430



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 4/92 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            PSPP   +  EI  + + + W+EP     + +  Y +E   I +  W ++ +   +   +
Sbjct: 501  PSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-YSLEKSVIGSGTWEAISSESPVRSPR 559

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             ++ +L+   SY FR  A+N+  +SD SE +E
Sbjct: 560  FAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSE 591



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435
            + +P PP      E+ ++S+ + W+ P   G   +  Y V +QE  + +W  ++   I+ 
Sbjct: 799  MPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISG 858

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            T   + +L+   SY F+  A+N   +   S  T+
Sbjct: 859  THLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTD 892



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 19/79 (24%), Positives = 38/79 (48%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T ++ G P PE+ W KN   +     Y +  +     I I+++    S +Y +   N  
Sbjct: 1358 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKY 1417

Query: 1652 GTSSVEVTLKVYDKPSKPE 1670
            G+ + +VT+ V+    +P+
Sbjct: 1418 GSETGQVTISVFKHGDEPK 1436



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 37/167 (22%), Positives = 67/167 (40%), Gaps = 12/167 (7%)

Query: 1320 EW-IVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            EW  VN+K I+  + T P + + K     ++ V     G      E++     + +    
Sbjct: 644  EWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVG------ESSAATEPIRVKQA- 696

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435
            L  PS P    +L    + + I W  P+  G   I+ Y ++  + +  +W +V    I  
Sbjct: 697  LATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPT 756

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
                + +L     Y FRA A N   + + S  +  ++  KE  +  P
Sbjct: 757  RVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFE-CKEWTMPQP 802



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 92/398 (23%), Positives = 152/398 (38%), Gaps = 51/398 (12%)

Query: 458  VQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKL--PVFEKPTSEEQSMAPIFVEK 515
            +Q    E+KG   AQ L D     Q     +++  DKL      K    ++   P F   
Sbjct: 1067 IQNLSEEDKGSYTAQ-LQDGKAKNQITLTLVDDDFDKLLRKADAKRRDWKRKQGPYFERP 1125

Query: 516  LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575
            L+ K T D       CQV      Q+T        K    FQ ++     A +   +  P
Sbjct: 1126 LQWKVTED-------CQV------QLTCKASVTNTKKETRFQWFFQR---AEMPDGQYDP 1169

Query: 576  EDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXADILEGIPP 634
            E      C+ + +    S   + I  A +SD  G + T+             ++  G   
Sbjct: 1170 ETGTGLLCIEEASL---SKKDKGIYRAMVSDDRGEDDTILDLTGDALDAIFTEL--GRIG 1224

Query: 635  TFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
              S  P K Q  +EG  I  + +   +      W  K + +   + I      D      
Sbjct: 1225 ALSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIW--- 1281

Query: 694  VLKITNVKKFQEGTYTV-VAVNRE---------GEA---SLPIVLKIKTG---EKEPPQV 737
             L I + K   +G YT+ +A  +E         G+A   ++    ++KT    EK   +V
Sbjct: 1282 -LHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKV 1340

Query: 738  IEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILK 793
            +  L  +  + + +++ L+  V G+P P I+W KN++PV  L     +  G   +ITI K
Sbjct: 1341 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEK 1400

Query: 794  PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
                +D G Y +  +N  G       I+V +  +E  E
Sbjct: 1401 VNS-EDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKE 1437



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 6/89 (6%)

Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPK 795
           PL+S  V +  +V+L+  V  +P P +TW KN+  +     ++      + + +  L+ +
Sbjct: 159 PLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIR 218

Query: 796 K--VKDEGVYTLKAENSEGIAETSAVITV 822
           +  ++D   YT++ +N+ G A + A + V
Sbjct: 219 RCAIEDSATYTVRVKNAHGQASSFAKVLV 247



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 9/97 (9%)

Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP------SETITQNFDGE 886
           P F    +   V E  T+ L   V  +P P +TWY+N+  I P         IT N+   
Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++E+    ++   DS  Y     N+ G++S  A+V +
Sbjct: 214 SLEIRRCAIE---DSATYTVRVKNAHGQASSFAKVLV 247


>UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundabout
           3 - Drosophila melanogaster (Fruit fly)
          Length = 1342

 Score =  103 bits (248), Expect = 4e-20
 Identities = 88/353 (24%), Positives = 152/353 (43%), Gaps = 25/353 (7%)

Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
           I +A  +D G    +            A +   + P   + P  Q V EG+ +   CR+ 
Sbjct: 180 IQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVG 239

Query: 659 AIPEPDIAWLFKGEE-IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             P PD+ WL       +P + +SV  +         L++  V    EG Y+  A N  G
Sbjct: 240 GDPMPDVLWLRTASGGNMPLDRVSVLEDRS-------LRLERVTIADEGEYSCEADNVVG 292

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC-KNNK--- 773
             +    L +      PP+ I+   S  V  G       + +GNP+PTI W  KNN    
Sbjct: 293 AITAMGTLTVYA----PPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLI 348

Query: 774 -----PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
                P+    + +  + HSI  L   +  D+ +  L    +E +A  ++ + +   ++E
Sbjct: 349 FPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNE-VASITSRVQLSLDSQE 407

Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
           +  PP+ I+     T+  K    L  +    P P+I+WYR+   + PS  +     G+  
Sbjct: 408 DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSGD-- 465

Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
            L+I+++D + D G Y CVAS+ AGKS+    + I++     +K  +   +T+
Sbjct: 466 -LIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTK 517



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 20/227 (8%)

Query: 734 PPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-----TKSDGDTH 787
           PP+++E P+ + + R  E   L+ +  G+P PTI W K+  P+K LP     T   G   
Sbjct: 22  PPRIVEHPIDTTVPRH-EPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLF 80

Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKE 846
            + ++  ++  D G+Y  +A+N  G+A + +A + V    +E    P      Q   + +
Sbjct: 81  FLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEP------QNTRIAQ 134

Query: 847 KGTIKLVARVTRN-PVPSITWYRNNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDY 904
             T  L     R  P P++TW +  + +        +  DG N  L I +   + D G Y
Sbjct: 135 GDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN--LAIQDA-RQTDEGQY 191

Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
           +C+A N  G     +  T+ V    ++          EG +V   C+
Sbjct: 192 QCIAKNPVG-VRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCR 237



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 80/317 (25%), Positives = 125/317 (39%), Gaps = 25/317 (7%)

Query: 828  ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN---EIISPSETITQNFD 884
            + + PP  +    + TV       L  +   +P P+I WY++    +I+  S  IT    
Sbjct: 18   QGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAG 77

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEG 943
            G    L + N   E D+G Y C A N  G + S  A + + V +  F    Q +    +G
Sbjct: 78   G-LFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNT-RIAQG 135

Query: 944  KTVILECQTSH-----TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
             T +LEC         TV+ K    K ++ G     I+  G             D G  +
Sbjct: 136  DTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN---LAIQDARQTDEGQYQ 192

Query: 999  CIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDG 1053
            CI K+    +E+S   +     P  IR   D  V E         +  +   DV+W R  
Sbjct: 193  CIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTA 252

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-VELPPEII 1110
                   ++    +    R L +   ++ DEGEYSC   +   + TA  T+ V  PP+ I
Sbjct: 253  SGGNMPLDRVSVLED---RSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFI 309

Query: 1111 TRLQNQKVNKGNKATFE 1127
             R  ++ V  G   +FE
Sbjct: 310  QRPASKSVELGADTSFE 326



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 103/445 (23%), Positives = 168/445 (37%), Gaps = 48/445 (10%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQF---SNHIQLTIDGKKQ 1161
            PP I+    +  V +   AT   +        ++W+KDG  ++    S+ I L   G   
Sbjct: 22   PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFF 81

Query: 1162 KLKIYDCDLD-DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT------DA 1214
             LK+ +   + DAG Y CE  N     +      ++   +   EF L P NT       A
Sbjct: 82   -LKVVNSRRETDAGIYWCEAKNE--LGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTA 138

Query: 1215 YLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             L    P    +  VTW KK     D E    +  V    L I+   + D+ +Y C+  +
Sbjct: 139  LLECAAPRGIPEPTVTW-KKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKN 197

Query: 1273 AKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
                  + L    V   P I+    +  +  G+ VT        P P+  W+  +     
Sbjct: 198  PVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNM 257

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGK 1386
                   ++ +S  L +++V   D G Y    +N  G       +T+   P     P  K
Sbjct: 258  PLDRVSVLEDRS--LRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASK 315

Query: 1387 PNILEIDSSSINICWDEPENT------GNSTIIYY----VVEYQEIDTTEWISVKNITKT 1436
               L  D+S        P+ T       NST+I+     +  +  ++T E  S+  +T+ 
Sbjct: 316  SVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRF 375

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494
            Q      +T+        A+NEV    AS T+     +   + + P +    P+ N T  
Sbjct: 376  Q------RTDKDLVILCNAMNEV----ASITSRVQLSLDSQEDRPPPIIISGPV-NQTLP 424

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDG 1519
                  L C   G+P P ++WYRDG
Sbjct: 425  IKSLATLQCKAIGLPSPTISWYRDG 449



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 79/328 (24%), Positives = 130/328 (39%), Gaps = 30/328 (9%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMHM 690
           PP   + P    V       L C+    P P I W   G   +I+P  +  + + +    
Sbjct: 22  PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSH-RITLPAGGLF 80

Query: 691 YCSVLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
           +   LK+ N ++  + G Y   A N  G A S    L++     E    +EP  + I  Q
Sbjct: 81  F---LKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDE--FRLEPQNTRIA-Q 134

Query: 749 GESVILS-AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVY 803
           G++ +L  A   G P PT+TW K  + +    +K     DG   +I   +  +  DEG Y
Sbjct: 135 GDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAI---QDARQTDEGQY 191

Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
              A+N  G+ E S++ T++   +     P  I    + TV E  ++    RV  +P+P 
Sbjct: 192 QCIAKNPVGVRE-SSLATLKVHVK-----PYIIRGPHDQTVLEGASVTFPCRVGGDPMPD 245

Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           + W R     +         +  ++ L    +    D G+Y C A N  G  +    +T+
Sbjct: 246 VLWLRTASGGNMPLDRVSVLEDRSLRLERVTI---ADEGEYSCEADNVVGAITAMGTLTV 302

Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQ 951
                   +   KS E   G     EC+
Sbjct: 303 YAPPKFIQRPASKSVEL--GADTSFECR 328



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 24/180 (13%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH-SSKYTIEASNTAGTSS- 1655
            G+P P + WY++G  ++   + NITT   +  + I +L R      YT  AS+ AG S+ 
Sbjct: 437  GLPSPTISWYRDGIPVQPSSKLNITT---SGDLIISDLDRQQDQGLYTCVASSRAGKSTW 493

Query: 1656 -----VEV----TLKVYDK------PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700
                 +E+     +K Y        PS P  P I+   +  ++TI W      G      
Sbjct: 494  SGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKIL-NATASALTIVWPTSDKAGASSFLG 552

Query: 1701 YAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758
            Y++E +  + +R WI +A        + ++ L +   YMF V A+N +GFS     SEPI
Sbjct: 553  YSVEMYCTNQSRTWIPIAS-RLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPI 611



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 19/214 (8%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----- 1538
            VE P+ + T   +E   L C   G P P + WY+DG  LK    ++              
Sbjct: 26   VEHPI-DTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKV 84

Query: 1539 --XXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                       Y C A N+ G       T  V  ++ +  +   N  I Q    GD  L+
Sbjct: 85   VNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQ----GDTALL 140

Query: 1593 T-AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
              A   GIP P V W K G KL+ +    +   +  + + I++ +++   +Y   A N  
Sbjct: 141  ECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN-LAIQDARQTDEGQYQCIAKNPV 199

Query: 1652 GT-SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            G   S   TLKV+ KP    GP     +   SVT
Sbjct: 200  GVRESSLATLKVHVKPYIIRGPHDQTVLEGASVT 233



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 12/172 (6%)

Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS- 1562
            G+P+P VTW + G+KL    + +    +                Y+CIA N  G  E+S 
Sbjct: 147  GIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSL 206

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK--NGNKLENDKEYN 1620
              + +  KP I     D  Q    G        + G P P+V+W +  +G  +  D+   
Sbjct: 207  ATLKVHVKPYIIRGPHD--QTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDR--- 261

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            ++  E  S +R++ +  +   +Y+ EA N  G  +   TL VY  P   + P
Sbjct: 262  VSVLEDRS-LRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRP 312



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 3/101 (2%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+E    PI +     +  P  S    +C+  G P P I+W+R    ++PS    +    
Sbjct: 405 SQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSG 464

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           D + + + R+   +D G +TCVA + AG ++ +  L +E P
Sbjct: 465 DLIISDLDRQ---QDQGLYTCVASSRAGKSTWSGFLRIELP 502



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISV-KNITKTQT 1438
            PS PG+P IL   +S++ I W   +  G S+ + Y VE Y    +  WI +   +++   
Sbjct: 519  PSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIF 578

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            ++++L   ++Y F   A N +  S  S  +E
Sbjct: 579  TVESLTQGAAYMFIVRAENSLGFSPPSPISE 609



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 5/114 (4%)

Query: 1948 VSLPTES--QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005
            + LPT    +  R  +    PS P  P  +    S + +  W T +  G +  LGY++ +
Sbjct: 499  IELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIV-WPTSDKAGASSFLGYSVEM 557

Query: 2006 RDVTKTM-WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                ++  W+ +    ++   F +  L++   YM  + A N +G S P    EP
Sbjct: 558  YCTNQSRTWIPIAS-RLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEP 610



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G++V F C+V G P P + W R  +      D     +D    +L +  V   D G ++
Sbjct: 228 EGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLED---RSLRLERVTIADEGEYS 284

Query: 583 CVAKNAAGFASSTTELIVEAP 603
           C A N  G  ++   L V AP
Sbjct: 285 CEADNVVGAITAMGTLTVYAP 305



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 42/155 (27%), Positives = 52/155 (33%), Gaps = 5/155 (3%)

Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK--PSQDFQ 557
           K T  + S  P  VE       P        C+ EG P P I W++    +K  P     
Sbjct: 13  KWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRI 72

Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH-GSEMTVXXX 616
                      V+      DAG + C AKN  G A S    +  A L D    E      
Sbjct: 73  TLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRI 132

Query: 617 XXXXXXXXXADILEGIP-PTFSKKPKAQYVD-EGS 649
                         GIP PT + K   Q +D EGS
Sbjct: 133 AQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGS 167



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 13/133 (9%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP II+   NQ +   + AT + + +      + W++DG  +Q S+ + +T  G    L 
Sbjct: 411  PPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSG---DLI 467

Query: 1165 IYDCD-LDDAGEYSC----EVGNSKCTAILTVE---EPSINFTLRLPEFILVPANTDAYL 1216
            I D D   D G Y+C      G S  +  L +E    P+I F  R PE    P+      
Sbjct: 468  ISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKF-YRAPEQTKCPSAPGQPK 526

Query: 1217 TVEIPDETLDVTW 1229
             +      L + W
Sbjct: 527  ILNATASALTIVW 539



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 1786 ITWFPSEKNGGSPIIDYKVEI--KQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYAR 1842
            I W  S+K G S  + Y VE+    + + W             ++ L+    Y F + A 
Sbjct: 537  IVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAE 596

Query: 1843 NEIGTSLPYTSDDKITIGK 1861
            N +G S P    + IT GK
Sbjct: 597  NSLGFSPPSPISEPITAGK 615


>UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC
            protein - Homo sapiens (Human)
          Length = 772

 Score =  103 bits (248), Expect = 4e-20
 Identities = 123/585 (21%), Positives = 221/585 (37%), Gaps = 34/585 (5%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXX 1541
            +++P   +  E  + +   C+  G P P  TW R  +  +L++ K +             
Sbjct: 177  LQRPSNVVAIEGKDAVLEGCV-SGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVT 235

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C+    +  +  S  + +   P       ++     +  E+  T  + G P 
Sbjct: 236  DDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECT--VSGKPV 293

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P V W KNG+ +     + I      S +RI  + +S    Y   A N AG +     L 
Sbjct: 294  PTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL- 349

Query: 1662 VYDKPSKPEGPVIMRE--------ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713
            +  KP+ P   V+           +S   V + W+PP +  G   T       E DN   
Sbjct: 350  IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRER 409

Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
                     ++   +  L     Y FRV+A N  G  E+ +   +  +  L VP      
Sbjct: 410  ALNTTQPGSLQ-LTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENL 468

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINT 1833
                     S+ ITW P     G P+  Y++   +     +          +++ L   T
Sbjct: 469  QAVST-SPTSILITWEPPAYANG-PVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFT 526

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
             Y  R  A N  G  +  ++DD   +  +  P + P+N  +    SRS+ + W  P S  
Sbjct: 527  EYSLRFLAYNRYGPGV--STDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGT 584

Query: 1894 GSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             +  IT Y I  +    +   ++ T+  +   +    +++  +  F++SA    G   P+
Sbjct: 585  QNGFITGYKIRHRKTTRRG--EMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPS 642

Query: 1953 ESQSVRLEKH----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008
               +    ++    + VP  P++ L +R   +N ++ SW TP  +    + GY I     
Sbjct: 643  NWYTAETPENDLDESQVPDQPSS-LHVR-PQTNCIIMSW-TPPLNPNIVVRGYIIGYG-- 697

Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
              + + E  +VD     ++I  L  +  Y+I + A N  G   PL
Sbjct: 698  VGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPL 742



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 150/723 (20%), Positives = 265/723 (36%), Gaps = 50/723 (6%)

Query: 1263 QCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            QCE +  L D+ S      +V V  P + +          G  V L  +    P P   W
Sbjct: 50   QCEAS--LGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHW 107

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDK 1380
              N + +         +   S +L I +++  D GIY+    N        E  V IL  
Sbjct: 108  QKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSD 167

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
            P    +   L+  S+ + I        G   ++   V      +  W+  + + + ++  
Sbjct: 168  PGLHRQLYFLQRPSNVVAI-------EGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKK 220

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE---TKIQSPTVEKPLKNITTEPNE 1497
             +L   S+        ++  +     T +   +      T +  P       N+    + 
Sbjct: 221  YSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESM 280

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            DIE  C   G P P V W ++G   + +                       Y+C+A N+ 
Sbjct: 281  DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEA 340

Query: 1557 GEVETSCVVGIQQKPVITISN------EDIK----QKHKVGDEWLVTAVIEG-IPPPEVI 1605
            G  +TS  + I  KP I  S+       D+         V   W   A  +G I    V 
Sbjct: 341  GNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVF 399

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            + + G+  E  +  N TT+  +  + +  LK      + + A N  G       +KV  +
Sbjct: 400  FSREGDNRE--RALN-TTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQ 456

Query: 1666 PS-KPEGPVI-MREISRE--SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            P  +  GPV  ++ +S    S+ I W+PP    G  +  Y +   E       K  +++ 
Sbjct: 457  PELQVPGPVENLQAVSTSPTSILITWEPPAYANG-PVQGYRLFCTEVSTG---KEQNIEV 512

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            D  +Y ++ L +  EY  R +A N  G    + ++ I + T  DVPS          +++
Sbjct: 513  DGLSYKLEGLKKFTEYSLRFLAYNRYG--PGVSTDDITVVTLSDVPSAPPQNVSLEVVNS 570

Query: 1782 ESVYITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRI 1839
             S+ ++W P      +  I  YK+  ++  ++ +           +   L   + Y F++
Sbjct: 571  RSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQV 630

Query: 1840 YARNEIGTSLP---YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             A    GT  P   YT++           P QP +  V   T+  + + WT P  N    
Sbjct: 631  SAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTN-CIIMSWT-PPLNPNIV 688

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQ 1955
            +  YII +    G  + + V V      + IE ++     +  + A N  G  +P  ES 
Sbjct: 689  VRGYIIGYGV--GSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESA 746

Query: 1956 SVR 1958
            + R
Sbjct: 747  TTR 749



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 20/280 (7%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G  +LL+C ++  P P I W    +++ P    S  +     +    L+I+ ++    G 
Sbjct: 88  GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVV----LPSGALQISRLQPGDIGI 143

Query: 708 YTVVAVN----REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
           Y   A N    R G  +   +L    G       ++   +++  +G+  +L   V G P 
Sbjct: 144 YRCSARNPASSRTGNEAEVRILS-DPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPP 202

Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           P+ TW +  + ++    K      S  ++      D G+YT            SA +TV 
Sbjct: 203 PSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV- 261

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
                   PP F+N    +   E   I+    V+  PVP++ W +N +++ PS+   Q  
Sbjct: 262 ------LVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYF-QIV 314

Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            G N+  ++  V S  D G Y+CVA N AG +   A++ +
Sbjct: 315 GGSNLR-ILGVVKS--DEGFYQCVAENEAGNAQTSAQLIV 351



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 83/326 (25%), Positives = 129/326 (39%), Gaps = 21/326 (6%)

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            K  EG Y   A    G++   I    K     P + +   +S+    G++V+L  +V+G 
Sbjct: 43   KPDEGLYQCEA--SLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGE 100

Query: 762  PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAV 819
            P PTI W KN + +  +P  S         L+  +++  D G+Y   A N    + T   
Sbjct: 101  PMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS-SRTGNE 159

Query: 820  ITVEEPTEENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
              V   ++      L F+ R   +   E     L   V+  P PS TW R  E+I     
Sbjct: 160  AEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSK 219

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                  G N  L+I+NV  + DSG Y CV +      S  A +T+ V    F+ H    Y
Sbjct: 220  KYSLLGGSN--LLISNVTDD-DSGMYTCVVTYKNENISASAELTVLVPP-WFLNHPSNLY 275

Query: 939  ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
               E   +  EC  S     +  W  N   +   D+ +I+                D G 
Sbjct: 276  -AYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGF 331

Query: 997  IKCIVKDQ----ETSTMLVV-KETIP 1017
             +C+ +++    +TS  L+V K  IP
Sbjct: 332  YQCVAENEAGNAQTSAQLIVPKPAIP 357



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 80/302 (26%), Positives = 115/302 (38%), Gaps = 35/302 (11%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G TV  +C+V G P P I W +    + P           + A L I  + P D G + C
Sbjct: 88  GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA-LQISRLQPGDIGIYRC 146

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            A+N A  +S T        LSD G    +                      F ++P   
Sbjct: 147 SARNPA--SSRTGNEAEVRILSDPGLHRQLY---------------------FLQRPSNV 183

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
              EG D +LE  +   P P   WL +GEE++   +   ++     +  S L I+NV   
Sbjct: 184 VAIEGKDAVLEGCVSGYPPPSFTWL-RGEEVIQLRSKKYSL-----LGGSNLLISNVTDD 237

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             G YT V   +    S    L +      PP  +    ++   +   +     V G P 
Sbjct: 238 DSGMYTCVVTYKNENISASAELTVLV----PPWFLNHPSNLYAYESMDIEFECTVSGKPV 293

Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           PT+ W KN   V            ++ IL   K  DEG Y   AEN  G A+TSA + V 
Sbjct: 294 PTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVK-SDEGFYQCVAENEAGNAQTSAQLIVP 352

Query: 824 EP 825
           +P
Sbjct: 353 KP 354



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 95/443 (21%), Positives = 174/443 (39%), Gaps = 42/443 (9%)

Query: 1083 DEGEYSC--ILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136
            DEG Y C   L D     S TA+V V   P   +++ ++     G+    + E+  G+ +
Sbjct: 45   DEGLYQCEASLGDSGSIISRTAKVAVAG-PLRFLSQTESVTAFMGDTVLLKCEVI-GEPM 102

Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA------I 1188
              + W K+  ++         +      L+I      D G Y C   N   +       +
Sbjct: 103  PTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEV 162

Query: 1189 LTVEEPSIN---FTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIE-DTEKFT 1243
              + +P ++   + L+ P  ++     DA L   +        TW + + VI+  ++K++
Sbjct: 163  RILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYS 222

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302
            L+       L+I   T+DD   YTCV+           E+ V  PP  +++         
Sbjct: 223  LLGG---SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYES 279

Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
             D+         P P   W+ N  ++    + +    S   +L I  V  +D G Y+   
Sbjct: 280  MDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGS---NLRILGVVKSDEGFYQCVA 336

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNI---------LEIDSSSINICWDEPENTGNSTII 1413
            EN  G+A     + I+ KP+ P    +         + + S  + + W  P     +   
Sbjct: 337  ENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQT 395

Query: 1414 YYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
            + V   +E D  E  ++       Q ++ NLK  + Y FR  A NE       E+++  K
Sbjct: 396  FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNE---WGPGESSQPIK 452

Query: 1473 VIKETKIQSPTVEKPLKNITTEP 1495
            V  + ++Q P   + L+ ++T P
Sbjct: 453  VATQPELQVPGPVENLQAVSTSP 475



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+      +  +   ++FEC V G P P + W +   ++ PS  FQ+       + L 
Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV----GGSNLR 320

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           I  V   D G + CVA+N AG A ++ +LIV  P
Sbjct: 321 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP 354



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G     E  V GYP P  TW R   +I+            N   L+I  V  +D+G +T
Sbjct: 187 EGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSN---LLISNVTDDDSGMYT 243

Query: 583 CVAKNAAGFASSTTELIVEAP 603
           CV        S++ EL V  P
Sbjct: 244 CVVTYKNENISASAELTVLVP 264


>UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA; n=1;
            Tribolium castaneum|Rep: PREDICTED: similar to CG8967-PA
            - Tribolium castaneum
          Length = 1094

 Score =  103 bits (247), Expect = 5e-20
 Identities = 146/668 (21%), Positives = 266/668 (39%), Gaps = 72/668 (10%)

Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV------ 1102
            WE +G  I     ++      HI ++        D G+++CI  D + +   ++      
Sbjct: 56   WELNGSKIANTTRRHQQGSNLHITRV----DRERDSGQFTCIAEDSTSSLAGSIRSSEAS 111

Query: 1103 --VELPPEIITRLQNQK----VNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLT 1155
              ++   E+  +LQ  +    +++G+  T        GD    WF++   +  S+ I++ 
Sbjct: 112  LNIQWIDEVSVQLQEPESASFISRGSDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEI- 170

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVP 1209
               KK++L I +    D G Y C   N      S     L V          +P   LVP
Sbjct: 171  ---KKKRLHIKNVGPSDNGVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVP 227

Query: 1210 ANTDAYLTVEIPDETLDVT-WYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
                AY   +   +  +VT WY KK    +E+ +KF + S+    TL I      DQ  Y
Sbjct: 228  QGGTAYFDCQY--QQAEVTEWYFKKDTRPLENGKKFVIHSN---GTLQINDVQGKDQGFY 282

Query: 1267 TCVLLDAKST-------TKLKVE------VVEFPPKIVDYEREYRIKRGSDVTLL-VDYQ 1312
            +CV + ++ST        +LK+       V  F P + +   +     G    L  ++  
Sbjct: 283  SCVGIRSESTEIPQSYIAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPD 342

Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372
            + P P  +W +N+         +  +D     L I+KV    AG Y    EN  G  +  
Sbjct: 343  SLP-PAKKWWLNTGGHTVSDSGEVRVDD--GRLIIEKVRMDHAGNYTCVAENMAGKTEKI 399

Query: 1373 MNVTILDKPSPPGKPNILEIDSS--SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
            + + +L+KP    +P  + +D +  S+  C  EP+N       + +V++++   +     
Sbjct: 400  IELVVLNKPVVTAQPLSVTVDENEPSMLTCDYEPKNH------FTIVKWRKDGKSLRHDF 453

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490
               +  +  I+  K N+S   R    ++          + ++ +         +EK LK 
Sbjct: 454  GENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISVIEK-LKF 512

Query: 1491 ITTEPNEDIELT------CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544
            +    N+ +EL       C   G P P +TW + G+    ++    N             
Sbjct: 513  VPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRIISMN-GTLVFNGVLNED 571

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y C+A N  G +  +  + +   P  ++  ++  +  + G    +  V+EG P P +
Sbjct: 572  KGKYTCVATNSQGVINVTINIDVVVAPKFSVEPKNPTEVTE-GQSVTIDCVVEGDPKPTI 630

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W KN     ND +++  T  +   + I E+ R   +KY   A N+AG +  EV L V+ 
Sbjct: 631  HWDKNLKM--NDFDHSRFTVLENGTLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHS 688

Query: 1665 KPS-KPEG 1671
            +    P+G
Sbjct: 689  RDGYHPDG 696



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 148/712 (20%), Positives = 281/712 (39%), Gaps = 85/712 (11%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            KE P   E  +++ V QG+SV L  +V      T  W  N   + A  T+      ++ I
Sbjct: 20   KEDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKI-ANTTRRHQQGSNLHI 78

Query: 792  LKPKKVKDEGVYTLKAENSE-----GIAETSAVITVEEPTE-----ENAEPPLFINRFQE 841
             +  + +D G +T  AE+S       I  + A + ++   E     +  E   FI+R  +
Sbjct: 79   TRVDRERDSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASFISRGSD 138

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            +T++             +      W+RN++ +  S+ I    + +   L I NV    D+
Sbjct: 139  VTLR--------CHTDASGDVHYEWFRNSDRLLKSDKI----EIKKKRLHIKNVGPS-DN 185

Query: 902  GDYKCVASNSAGK--SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959
            G Y+C+A+N+AG   S+    + +  E+   ++ + +     +G T   +CQ      T+
Sbjct: 186  GVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTE 245

Query: 960  WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETIPE 1018
            WY  KK+   +++ +                  D G   C+ ++ + T       E    
Sbjct: 246  WYF-KKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSEST-------EIPQS 297

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDG---------EIIKPKK------NKY 1063
            +I +L+   + E  V   E  ++  +  VV    G         + + P K        +
Sbjct: 298  YIAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGH 357

Query: 1064 DFEKRGHIR----KLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITRLQ--- 1114
                 G +R    +L I    +   G Y+C+  + +   E  + +V L   ++T      
Sbjct: 358  TVSDSGEVRVDDGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSV 417

Query: 1115 NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS------NHIQLTIDGKKQKLKIYDC 1168
                N+ +  T + E      +V+W KDG  ++        +  ++ I      L I + 
Sbjct: 418  TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477

Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--TVEIPDETLD 1226
            +  D GEY CEV       +L+  EP+    +   +F+  P N    L    ++  +   
Sbjct: 478  ESHDRGEYVCEVLAKGFEPVLS--EPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQG 535

Query: 1227 -----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKL 1279
                 +TW K   + E  +   +IS     TL+      +D+ +YTCV  +++      +
Sbjct: 536  TPPPIITWEK---LGESFDNSRIIS--MNGTLVFNGVLNEDKGKYTCVATNSQGVINVTI 590

Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
             ++VV  P   V+ +    +  G  VT+    +  P+P   W  N K +    H++ ++ 
Sbjct: 591  NIDVVVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLK-MNDFDHSRFTV- 648

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNI 1389
             ++ +L I +V   D   Y     N+ G    +V++ V   D   P G   +
Sbjct: 649  LENGTLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHSRDGYHPDGDSTV 700



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 152/707 (21%), Positives = 267/707 (37%), Gaps = 88/707 (12%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568
            P F E  R      G +V   C+V   P   +T++ +    K +   + +    N+  T 
Sbjct: 23   PYFSESPRNVDVVQGKSVTLPCKVT--PGIGMTYYWELNGSKIANTTRRHQQGSNLHITR 80

Query: 569  VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
            V RE    D+G FTC+A++      ST+ L      S   SE ++               
Sbjct: 81   VDRE---RDSGQFTCIAED------STSSLAG----SIRSSEASLNIQW----------- 116

Query: 629  LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
            ++ +     +   A ++  GSD+ L C   A  +    W    + ++  + I +  +   
Sbjct: 117  IDEVSVQLQEPESASFISRGSDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEIKKKR-- 174

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
                  L I NV     G Y  +A N  G         +    +E   +    +  +V Q
Sbjct: 175  ------LHIKNVGPSDNGVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQ 228

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYT-- 804
            G +     Q     +  +T     K  + L        HS   L+   V  KD+G Y+  
Sbjct: 229  GGTAYFDCQY---QQAEVTEWYFKKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCV 285

Query: 805  -LKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             +++E++E     IAE   +  + E T  + EPPL  N   ++   E G  +L      +
Sbjct: 286  GIRSESTEIPQSYIAELK-LAYLSEFTVNSFEPPLSENS-NQVVAPEGGLFQLTCLEPDS 343

Query: 860  PVPSITWYRN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
              P+  W+ N     +S S  +  + DG    L+I  V  +  +G+Y CVA N AGK+  
Sbjct: 344  LPPAKKWWLNTGGHTVSDSGEVRVD-DG---RLIIEKVRMD-HAGNYTCVAENMAGKTEK 398

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ---TSHTVSTKWYHNKKEI------S 968
               + +  + V   + L  S   +E +  +L C     +H    KW  + K +      +
Sbjct: 399  IIELVVLNKPVVTAQPL--SVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGEN 456

Query: 969  GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP-----EFIRKL 1023
             +D + I                 D G   C V  +    +L    TI      +F+   
Sbjct: 457  SLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPP 516

Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
             + +++   VA +  +       ++ WE+ GE      N       G    L        
Sbjct: 517  VNKKLELGSVAKVHCKAQGTPPPIITWEKLGESF---DNSRIISMNG---TLVFNGVLNE 570

Query: 1083 DEGEYSCILRDESCTAEVTV---VELPPEIITRLQN-QKVNKGNKATFEIELTKGD--AL 1136
            D+G+Y+C+  +      VT+   V + P+     +N  +V +G   T +  + +GD    
Sbjct: 571  DKGKYTCVATNSQGVINVTINIDVVVAPKFSVEPKNPTEVTEGQSVTIDC-VVEGDPKPT 629

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            + W K+     F +H + T+  +   L I +   +D  +Y C  GNS
Sbjct: 630  IHWDKNLKMNDF-DHSRFTV-LENGTLFISEVHREDENKYGCTAGNS 674



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 136/618 (22%), Positives = 245/618 (39%), Gaps = 69/618 (11%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            E P F    + + V +  ++ L  +VT     +  W  N   I+   T  ++  G N+  
Sbjct: 21   EDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKIA--NTTRRHQQGSNLH- 77

Query: 891  VITNVDSEIDSGDYKCVASNSAGK---SSHGARVTIDVEKVTFVK-HLQKSYET---EEG 943
             IT VD E DSG + C+A +S      S   +  +++++ +  V   LQ+         G
Sbjct: 78   -ITRVDRERDSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASFISRG 136

Query: 944  KTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
              V L C T  S  V  +W+ N   +   D  EI    +            D GV +C+ 
Sbjct: 137  SDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEI----KKKRLHIKNVGPSDNGVYRCLA 192

Query: 1002 KD------QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEI-NSETADVVWERDG 1053
             +        T+  L V       I+ + +D  V +   A  + +   +E  +  +++D 
Sbjct: 193  NNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTEWYFKKDT 252

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI-LRDESC------TAEVTVVELP 1106
              ++  K K+     G    L I +    D+G YSC+ +R ES        AE+ +  L 
Sbjct: 253  RPLENGK-KFVIHSNG---TLQINDVQGKDQGFYSCVGIRSESTEIPQSYIAELKLAYLS 308

Query: 1107 PEIITRLQNQKVNKGNKAT------FEIELTKGDAL---VRWFKDGSEIQFSNHIQLTID 1157
               +   +       N+        F++   + D+L    +W+ +      S+  ++ +D
Sbjct: 309  EFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVRVD 368

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
                +L I    +D AG Y+C   N   K   I+ +   +       P  + V  N  + 
Sbjct: 369  --DGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSVTVDENEPSM 426

Query: 1216 LTVEI-PDETLDVTWYKK--KSVIEDTEKFTL----ISDVK-KRTLIIRKCTEDDQCEYT 1267
            LT +  P     +  ++K  KS+  D  + +L    I   K   +L+IR+    D+ EY 
Sbjct: 427  LTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYV 486

Query: 1268 CVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            C +L    +   +    + V+E   K V      +++ GS   +    Q  P P   W  
Sbjct: 487  CEVLAKGFEPVLSEPATISVIE-KLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITW-- 543

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
              K+ +   +++  I S + +L    V N D G Y     N+ G  +V +N+ ++  P  
Sbjct: 544  -EKLGESFDNSR--IISMNGTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAPKF 600

Query: 1384 PGKP-NILEI-DSSSINI 1399
              +P N  E+ +  S+ I
Sbjct: 601  SVEPKNPTEVTEGQSVTI 618



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 17/185 (9%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           L+ +PP  +KK     ++ GS   + C+    P P I W   GE       IS+      
Sbjct: 510 LKFVPPPVNKK-----LELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRIISMN----- 559

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
                 L    V    +G YT VA N +G  ++ I + +      P   +EP     V +
Sbjct: 560 ----GTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVA---PKFSVEPKNPTEVTE 612

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808
           G+SV +   V G+P+PTI W KN K      ++     +    +     +DE  Y   A 
Sbjct: 613 GQSVTIDCVVEGDPKPTIHWDKNLKMNDFDHSRFTVLENGTLFISEVHREDENKYGCTAG 672

Query: 809 NSEGI 813
           NS G+
Sbjct: 673 NSAGL 677



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 78/322 (24%), Positives = 117/322 (36%), Gaps = 23/322 (7%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
           LI+E    DH    T              +++    P  + +P +  VDE    +L C  
Sbjct: 372 LIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSVTVDENEPSMLTCDY 431

Query: 658 VAIPEPDIA-WLFKGEEIVPD--ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
                  I  W   G+ +  D  EN        +  + + L I   +    G Y    + 
Sbjct: 432 EPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLA 491

Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKP 774
           +  E  L     I   EK   + + P  +  +  G    +  +  G P P ITW K  + 
Sbjct: 492 KGFEPVLSEPATISVIEKL--KFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGES 549

Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834
                  S   T    +      +D+G YT  A NS+G+   +  I V    + + EP  
Sbjct: 550 FDNSRIISMNGT---LVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAPKFSVEP-- 604

Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN---NEIISPSETITQNFDGENIELV 891
                 E+T  +  TI  V  V  +P P+I W +N   N+      T+      EN  L 
Sbjct: 605 --KNPTEVTEGQSVTIDCV--VEGDPKPTIHWDKNLKMNDFDHSRFTVL-----ENGTLF 655

Query: 892 ITNVDSEIDSGDYKCVASNSAG 913
           I+ V  E D   Y C A NSAG
Sbjct: 656 ISEVHRE-DENKYGCTAGNSAG 676



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 508 MAPIF-VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           +AP F VE   P    +G +V  +C VEG P+P I W +   +     D   +   +N  
Sbjct: 596 VAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKM--NDFDHSRFTVLEN-G 652

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
           TL I EV  ED   + C A N+AG      +LIV +
Sbjct: 653 TLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHS 688



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 7/109 (6%)

Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555
           PV  +P +        FV     K    GS  +  C+ +G P P ITW +       S+ 
Sbjct: 496 PVLSEPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRI 555

Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
             M        TLV   V  ED G +TCVA N+ G  + T  + +V AP
Sbjct: 556 ISMN------GTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAP 598



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 3/94 (3%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           S  P   E       P+G   Q  C       P   W+  T     S   ++  DD    
Sbjct: 314 SFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVRVDDGR-- 371

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            L+I +V  + AG +TCVA+N AG      EL+V
Sbjct: 372 -LIIEKVRMDHAGNYTCVAENMAGKTEKIIELVV 404


>UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1463

 Score =  103 bits (247), Expect = 5e-20
 Identities = 96/381 (25%), Positives = 153/381 (40%), Gaps = 29/381 (7%)

Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658
           I EA  SD G    V            A +   + P   + P+ Q    GS ++ +CR+ 
Sbjct: 248 IQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIG 307

Query: 659 AIPEPDIAWLFKGE-EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             P PD+ W        +P   + V  +         LK+ +V     G YT  A N  G
Sbjct: 308 GDPLPDVLWRRTASGGNMPLRRVHVLEDRS-------LKLDDVTLEDMGEYTCEADNAVG 360

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
             +   +L +      PP+ +   K+ +V  G+ V+   Q  G+PRPT+ W         
Sbjct: 361 GITATGILTVHA----PPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLL 416

Query: 778 LPTKSDG--------DTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEEPTEE 828
           LP   DG        +  S+  +     +D G V T  A N+ G   +  V++V+  T+ 
Sbjct: 417 LPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVD--TQF 474

Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888
              PP+        T+  K  + L  R    PVP ++WY +   I   E   +N      
Sbjct: 475 ELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAG- 533

Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ----KSYETEEGK 944
            L I+++    D G Y CVASN  GKSS    + +D      +K  +     +Y    GK
Sbjct: 534 ALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGK 593

Query: 945 TVILECQTSHTVSTKWYHNKK 965
             ++E +  ++V+  W  + K
Sbjct: 594 PQMVE-KGENSVTLSWTRSNK 613



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 142/578 (24%), Positives = 234/578 (40%), Gaps = 69/578 (11%)

Query: 949  ECQTSHTVSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXXX-XDVGVIKCIVKDQ- 1004
            + + + T + +W+ + +E+      HR ++  G              D G   C  K++ 
Sbjct: 113  QAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFLKVIHSRRESDAGTYWCEAKNEF 172

Query: 1005 ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKP 1058
                  +  L V     EF  +  +  V + +VA++E      S    + W ++G+ +  
Sbjct: 173  GVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNL 232

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD-----ESCTAEVTVVELPPEIITRL 1113
              NK      G    L I+     D+G Y C++++     ES TA + V  + P +I   
Sbjct: 233  VGNKRIRIVDGG--NLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKV-HVRPFLIRGP 289

Query: 1114 QNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
            QNQ    G+   F+  +  GD L  V W +  S           ++ +   LK+ D  L+
Sbjct: 290  QNQTAVVGSSVVFQCRIG-GDPLPDVLWRRTASGGNMPLRRVHVLEDRS--LKLDDVTLE 346

Query: 1172 DAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDET 1224
            D GEY+CE    VG    T ILTV  P   F +R P+  LV    +     +    P  T
Sbjct: 347  DMGEYTCEADNAVGGITATGILTVHAPP-KFVIR-PKNQLVEIGDEVLFECQANGHPRPT 404

Query: 1225 LDVTWYKKKSVI-----EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KS 1275
            L  +     S++     +   + TL  + +    I R   ED     TC  L+A     S
Sbjct: 405  LYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSS 464

Query: 1276 TTKLKVEV-VEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
             T + V+   E PP I++       +   S V L       P P   W ++   I   +H
Sbjct: 465  RTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEH 524

Query: 1334 TKPSIDSKSASLTIKKVE-NTDAGIYKLRLENNCGHA--------DVEMNVTI------- 1377
             + ++ S + +LTI  ++ + D G+Y     N  G +        D   N  I       
Sbjct: 525  ERRNL-SDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPE 583

Query: 1378 -LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWIS----VK 1431
                P PPGKP ++E   +S+ + W      G S+++ YV+E + + +T  W++    V+
Sbjct: 584  LSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQ 643

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            N T TQT    L    +Y F   A N   +S  S  +E
Sbjct: 644  NTTFTQT---GLLPGVNYFFLIRAENSHGLSLPSPMSE 678



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 75/330 (22%), Positives = 130/330 (39%), Gaps = 22/330 (6%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESD 687
           L+G  P   + P    V +       C+    P P I W   G E+  D  +  + + + 
Sbjct: 86  LKGENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAG 145

Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIV 746
              +  V  I + ++   GTY   A N  G A S    L++     E    +EP  +  V
Sbjct: 146 GLFFLKV--IHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDE--FRLEPANTR-V 200

Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVY 803
            QGE  ++      G+P P I+W KN + +  +  K     D  ++ I + ++  D+G Y
Sbjct: 201 AQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQ-SDDGRY 259

Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
               +N  G  E++               P  I   Q  T     ++    R+  +P+P 
Sbjct: 260 QCVVKNVVGTRESATAFLKVHVR------PFLIRGPQNQTAVVGSSVVFQCRIGGDPLPD 313

Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           + W R       +  + +    E+  L + +V  E D G+Y C A N+ G  +    +T+
Sbjct: 314 VLWRRTAS--GGNMPLRRVHVLEDRSLKLDDVTLE-DMGEYTCEADNAVGGITATGILTV 370

Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTS 953
                  ++   K+   E G  V+ ECQ +
Sbjct: 371 HAPPKFVIR--PKNQLVEIGDEVLFECQAN 398



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 70/316 (22%), Positives = 128/316 (40%), Gaps = 25/316 (7%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGEN 887
            E P  I    + TV +        +   NP P+I W+++   +  ++T +       G  
Sbjct: 89   ENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELK-TDTGSHRIMLPAGGL 147

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-ETEEGKTV 946
              L + +   E D+G Y C A N  G +      T+ V  +     L+ +     +G+  
Sbjct: 148  FFLKVIHSRRESDAGTYWCEAKNEFGVA-RSRNATLQVAFLRDEFRLEPANTRVAQGEVA 206

Query: 947  ILEC---QTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVK 1002
            ++EC   + S      W  N + ++ + ++ I I +G             D G  +C+VK
Sbjct: 207  LMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDG--GNLAIQEARQSDDGRYQCVVK 264

Query: 1003 D----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIK 1057
            +    +E++T  +     P  IR  Q+         + +  I  +   DV+W R      
Sbjct: 265  NVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGN 324

Query: 1058 -PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE-VTVVELPPEIITRL 1113
             P +  +  E R     L + + ++ D GEY+C   +     TA  +  V  PP+ + R 
Sbjct: 325  MPLRRVHVLEDRS----LKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRP 380

Query: 1114 QNQKVNKGNKATFEIE 1129
            +NQ V  G++  FE +
Sbjct: 381  KNQLVEIGDEVLFECQ 396



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 62/227 (27%), Positives = 99/227 (43%), Gaps = 37/227 (16%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPS-QD--FQMYYDDDN 564
           P FV + + +    G  V FECQ  G+PRP + W  +  ++++ P  +D   ++    + 
Sbjct: 374 PKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEG 433

Query: 565 VATLVIREVFPEDAG-TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623
            + L I     ED+G   TC A NA G  SS T + V+                      
Sbjct: 434 RSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQ-------------------- 473

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
                 E  PP   + P  Q +   S ++L CR +  P P ++W   G  I   E+    
Sbjct: 474 -----FELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRN 528

Query: 684 IESDMHMYCSVLKITNVKKFQ-EGTYTVVAVNREGEASLPIVLKIKT 729
           + SD       L I+++++ + EG YT VA NR G++S    L++ T
Sbjct: 529 L-SD----AGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDT 570



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 80/310 (25%), Positives = 113/310 (36%), Gaps = 42/310 (13%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTW------------YRDGKKLKTAKATYENRXXXX 1536
            KN   E  +++   C   G P+P + W            YRDG+   T   T E R    
Sbjct: 381  KNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTL--TPEGRSVLS 438

Query: 1537 XXXXXXXXXXXY-KCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLV 1592
                          C A N  G V +  VV +  +   P   I    + Q   V    ++
Sbjct: 439  IARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVL 498

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTA 1651
                 G P P+V WY +G  ++  +E+          + I +L+R      YT  ASN  
Sbjct: 499  PCRTLGTPVPQVSWYLDGIPID-VQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRN 557

Query: 1652 GTSS----------VEVTLKVYDKPS-----KPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            G SS              +K +  P       P G   M E    SVT+ W      GG 
Sbjct: 558  GKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGS 617

Query: 1697 ELTKYAIE---KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EA 1752
             L  Y IE   K+E D   W+ V    ++  T+    L     Y F + A+N  G S  +
Sbjct: 618  SLVGYVIEMFGKNETDG--WVAVGTRVQNT-TFTQTGLLPGVNYFFLIRAENSHGLSLPS 674

Query: 1753 LESEPIVIKT 1762
              SEPI + T
Sbjct: 675  PMSEPITVGT 684



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 77/332 (23%), Positives = 120/332 (36%), Gaps = 26/332 (7%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDF--EKRGHIRK 1073
            P  I    D  V + D      +     T  + W +DG  +K     +       G    
Sbjct: 91   PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150

Query: 1074 LYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
              I +    D G Y C  ++E     S  A + V  L  E      N +V +G  A  E 
Sbjct: 151  KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMEC 210

Query: 1129 ELTKG--DALVRWFKDGSEIQFSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGN--- 1182
               +G  +  + W K+G  +    + ++ I DG    L I +    D G Y C V N   
Sbjct: 211  GAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGN--LAIQEARQSDDGRYQCVVKNVVG 268

Query: 1183 --SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDT 1239
                 TA L V      F +R P+       +       I  + L DV W  +++     
Sbjct: 269  TRESATAFLKVHVRP--FLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLW--RRTASGGN 324

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDYEREYR 1298
                 +  ++ R+L +   T +D  EYTC   +A    T   +  V  PPK V   +   
Sbjct: 325  MPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQL 384

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIV--NSKII 1328
            ++ G +V         P+P   W V  NS ++
Sbjct: 385  VEIGDEVLFECQANGHPRPTLYWSVEGNSSLL 416



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 50/216 (23%), Positives = 83/216 (38%), Gaps = 19/216 (8%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----- 1538
            +E P+ + T   N+     C   G P P + W++DG++LKT   ++              
Sbjct: 94   IEHPM-DTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFLKV 152

Query: 1539 --XXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                       Y C A N+ G       T  V  ++ +  +  +N  + Q    G+  L+
Sbjct: 153  IHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQ----GEVALM 208

Query: 1593 TA-VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
                  G P P++ W KNG  L       I   +  + + I+E ++S   +Y     N  
Sbjct: 209  ECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGN-LAIQEARQSDDGRYQCVVKNVV 267

Query: 1652 GT-SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            GT  S    LKV+ +P    GP     +   SV  +
Sbjct: 268  GTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQ 303



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 75/391 (19%), Positives = 137/391 (35%), Gaps = 27/391 (6%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P+I+++  +  + +    T     +  P P  +W  + + +K    +   +        +
Sbjct: 91   PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150

Query: 1348 KKVEN---TDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            K + +   +DAG Y    +N  G A   +  + V  L +     +P    +    + +  
Sbjct: 151  KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFL-RDEFRLEPANTRVAQGEVALME 209

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
                       I +    Q ++      ++ +     +IQ  + +   R++    N V  
Sbjct: 210  CGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGT 269

Query: 1462 SDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--D 1518
             +++  T + KV ++   I+ P      +N T      +   C  GG P P V W R   
Sbjct: 270  RESA--TAFLKVHVRPFLIRGP------QNQTAVVGSSVVFQCRIGGDPLPDVLWRRTAS 321

Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578
            G  +   +                     Y C A N  G +  + ++ +   P   I  +
Sbjct: 322  GGNMPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPK 381

Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-----ENDKEYNIT-TKEKTSVIRI 1632
            +  Q  ++GDE L      G P P + W   GN         D    +T T E  SV+ I
Sbjct: 382  N--QLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSI 439

Query: 1633 KELKRSHSSK-YTIEASNTAGTSSVEVTLKV 1662
                R  S K  T  A N  G+ S    + V
Sbjct: 440  ARFAREDSGKVVTCNALNAVGSVSSRTVVSV 470



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 3/80 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS+V F+C++ G P P + W R+TA        +++  +D   +L + +V  ED G +TC
Sbjct: 297 GSSVVFQCRIGGDPLPDVLW-RRTASGGNMPLRRVHVLEDR--SLKLDDVTLEDMGEYTC 353

Query: 584 VAKNAAGFASSTTELIVEAP 603
            A NA G  ++T  L V AP
Sbjct: 354 EADNAVGGITATGILTVHAP 373



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 3/105 (2%)

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-MWMEV 2016
            R  + +T P PP  P  +   G N V  SW      GG+ L+GY I +    +T  W+ V
Sbjct: 580  RAPELSTYPGPPGKPQMVEK-GENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAV 638

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            G    NT  F    L     Y   I A N  GLS P    EP  V
Sbjct: 639  GTRVQNT-TFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITV 682



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATL 568
           P  +E       P      F CQ EG P P I WF+    +K  +   ++      +  L
Sbjct: 91  PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150

Query: 569 -VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
            VI      DAGT+ C AKN  G A S    +  A L D
Sbjct: 151 KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRD 189



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 9/91 (9%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923
            PP +P+   + E    SVTL WT     GGS +  Y+IE F   +   W   V VG  V 
Sbjct: 590  PPGKPQ---MVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGW---VAVGTRVQ 643

Query: 1924 EHCI--ENIKEKDEIIFRISAENTVGVSLPT 1952
                    +       F I AEN+ G+SLP+
Sbjct: 644  NTTFTQTGLLPGVNYFFLIRAENSHGLSLPS 674



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWKXXXXXXXXXARIQK-LSINTTYQFRI 1839
            SV ++W  S K GGS ++ Y +E+  K E   W             Q  L     Y F I
Sbjct: 603  SVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLI 662

Query: 1840 YARNEIGTSLPYTSDDKITIG 1860
             A N  G SLP    + IT+G
Sbjct: 663  RAENSHGLSLPSPMSEPITVG 683



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           P  S V   C+  G P PQ++W+     I   +  +    D    T+   +   ED G +
Sbjct: 491 PVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRH-EDEGLY 549

Query: 582 TCVAKNAAGFASSTTELIVEAP 603
           TCVA N  G +S +  L ++ P
Sbjct: 550 TCVASNRNGKSSWSGYLRLDTP 571



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 5/88 (5%)

Query: 515 KLRPKHT--PDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571
           +L P +T    G     EC    G P PQI+W +    +    + ++   D     L I+
Sbjct: 192 RLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGG--NLAIQ 249

Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELI 599
           E    D G + CV KN  G   S T  +
Sbjct: 250 EARQSDDGRYQCVVKNVVGTRESATAFL 277



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 33/164 (20%), Positives = 66/164 (40%), Gaps = 8/164 (4%)

Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-S 1562
            G P+P+++W ++G+ L      +    +                Y+C+  N  G  E+ +
Sbjct: 215  GSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESAT 274

Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622
              + +  +P +    ++  Q   VG   +    I G P P+V+W +  +   N     + 
Sbjct: 275  AFLKVHVRPFLIRGPQN--QTAVVGSSVVFQCRIGGDPLPDVLWRRTASG-GNMPLRRVH 331

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
              E  S +++ ++      +YT EA N  G  +    L V+  P
Sbjct: 332  VLEDRS-LKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPP 374


>UniRef50_Q15772 Cluster: Striated muscle preferentially expressed
            protein kinase; n=26; Theria|Rep: Striated muscle
            preferentially expressed protein kinase - Homo sapiens
            (Human)
          Length = 3223

 Score =  103 bits (247), Expect = 5e-20
 Identities = 112/449 (24%), Positives = 185/449 (41%), Gaps = 38/449 (8%)

Query: 504  EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
            EE   AP+F   L+      G+ V  +C +   P PQ++W +  + ++ S+   +   + 
Sbjct: 716  EEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALR-SEGRLLLRAEG 774

Query: 564  NVATLVIREVFPEDAGTF-----------TCVAK-------NAAGFASSTT---ELIV-- 600
               TL++RE    DAG++           TC A        + + F+S  T   E +   
Sbjct: 775  ERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPP 834

Query: 601  -EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA 659
             E P        T             +D     PPTF      Q V EG D+++  R+  
Sbjct: 835  EEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQG 894

Query: 660  IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719
             P+P ++WL   + + PD+    A E++  + C  L+I   ++   G YT  AVN  G  
Sbjct: 895  EPKPVVSWLRNRQPVRPDQR-RFAEEAEGGL-CR-LRILAAERGDAGFYTCKAVNEYGAR 951

Query: 720  SLPIVLKIKT-GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKPVKA 777
                 L+++   E     V+ PL+ + V  GE  +    V G     + W C+      A
Sbjct: 952  QCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA 1011

Query: 778  -LPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
             L  K   D     +L     +D+ GVYT K   ++     SA +TV       +  PLF
Sbjct: 1012 LLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRP-----SLAPLF 1066

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
                +++ V E    +   +++  P P +TW      +  SE +    DG    L I +V
Sbjct: 1067 TRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHV 1126

Query: 896  DSEIDSGDYKCVASNSAGKSSHGARVTID 924
             SE D G Y   A N+ G++   A++ ++
Sbjct: 1127 GSE-DEGLYAVSAVNTHGQAHCSAQLYVE 1154



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 69/259 (26%), Positives = 115/259 (44%), Gaps = 13/259 (5%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDG 784
            TG K PP     L    VR+G+ VI+S +V G P+P ++W +N +PV    +    +++G
Sbjct: 863  TGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEG 922

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
                + IL  ++  D G YT KA N  G  +  A + V    E  +   L     Q++ V
Sbjct: 923  GLCRLRILAAER-GDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVL--APLQDVDV 979

Query: 845  KEKGTIKLVARVTRNPVP-SITWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDSG 902
               G + L   +   P    + W     ++ P+      +FDG   +L++T+V  E DSG
Sbjct: 980  -GAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSV-HEDDSG 1037

Query: 903  DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKW 960
             Y C  S +  + +  AR+T+          L +  E  EG+    +C+ S T      W
Sbjct: 1038 VYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTW 1097

Query: 961  YHNKKEISGMDHREIIQEG 979
             H    +   ++  + Q+G
Sbjct: 1098 THFGCPMEESENLRLRQDG 1116



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 61/250 (24%), Positives = 102/250 (40%), Gaps = 7/250 (2%)

Query: 487  KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
            KL+   D+L    + T    S+AP+F   L      +G   +F+C++ G P P +TW   
Sbjct: 1042 KLSTAKDELTCSARLTVRP-SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHF 1100

Query: 547  TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
               ++ S++ ++   D  + +L I  V  ED G +   A N  G A  + +L VE P + 
Sbjct: 1101 GCPMEESENLRL-RQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA 1159

Query: 607  HGSEMTVXXXXXXXXXXXXADILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665
                 +                LE +  P F +  +   V    + +LEC++  +P P I
Sbjct: 1160 ASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTI 1219

Query: 666  AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            +W   G  I   ++  +    D+H     L    V     G Y  V  N+ G+A+    L
Sbjct: 1220 SWFHNGHRIQSSDDRRMTQYRDVHR----LVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1275

Query: 726  KIKTGEKEPP 735
             +      PP
Sbjct: 1276 YVTDVVPGPP 1285



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 75/302 (24%), Positives = 122/302 (40%), Gaps = 40/302 (13%)

Query: 645  VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVK 701
            V  G   L EC +    + ++ WL +G  + P       ++  MH     C +L +T+V 
Sbjct: 979  VGAGEMALFECLVAGPTDVEVDWLCRGRLLQP-----ALLKCKMHFDGRKCKLL-LTSVH 1032

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            +   G YT      + E +    L ++      P     L+ + V +G +     ++ G 
Sbjct: 1033 EDDSGVYTCKLSTAKDELTCSARLTVRPSLA--PLFTRLLEDVEVLEGRAARFDCKISGT 1090

Query: 762  PRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            P P +TW     P++    L  + DG  HS+ I      +DEG+Y + A N+ G A  SA
Sbjct: 1091 PPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGS-EDEGLYAVSAVNTHGQAHCSA 1149

Query: 819  VITVEEPTEENAEP------------------------PLFINRFQEITVKEKGTIKLVA 854
             + VEEP    + P                        P F+   Q++ V       L  
Sbjct: 1150 QLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLEC 1209

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            +VT  P P+I+W+ N   I  S+        +   LV   V  +  +G YK V +N  GK
Sbjct: 1210 QVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQ-HAGVYKSVIANKLGK 1268

Query: 915  SS 916
            ++
Sbjct: 1269 AA 1270



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 74/371 (19%), Positives = 137/371 (36%), Gaps = 18/371 (4%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374
            P P   W  N   I+     + +       L    V    AG+YK  + N  G A    +
Sbjct: 1215 PYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAH 1274

Query: 1375 VTILDK-PSPP-GKPNILEIDSSSINICWDEPENTG---NSTIIYYVVEYQEIDTTEWIS 1429
            + + D  P PP G P ++ +    + + W+ P +     +   + Y V++Q + + +W +
Sbjct: 1275 LYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTA 1334

Query: 1430 -VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKIQSPTVEK 1486
             V  + +   +   L+    + FR  +      S  S  +E  ++++   T  ++P +  
Sbjct: 1335 LVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLD 1394

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE------NRXXXXXXX 1539
                +     +   +T  F  V + +V W    G  L+     YE      ++       
Sbjct: 1395 KPDIVYVVEGQPASVTVTFNHV-EAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICR 1453

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                      C A N HG    S  + + + P      ED++     G+      V+EG 
Sbjct: 1454 VSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVG--AGETARFAVVVEGK 1511

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P+++WYK+   L      +   +E    + +          YT  A N AG  S +  
Sbjct: 1512 PLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAE 1571

Query: 1660 LKVYDKPSKPE 1670
            L V+   +  E
Sbjct: 1572 LAVHSAQTAME 1582



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 73/267 (27%), Positives = 112/267 (41%), Gaps = 18/267 (6%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F   L D  V+E    I+ + +  E   VV W R+ + ++P + ++  E  G + +L 
Sbjct: 869  PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928

Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE----IITRLQNQKVNKGNKATFE 1127
            I      D G Y+C   +E     C A + V   P      ++  LQ+  V  G  A FE
Sbjct: 929  ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFE 988

Query: 1128 IELTKG--DALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
              L  G  D  V W   G  +Q +    ++  DG+K KL +     DD+G Y+C++  +K
Sbjct: 989  C-LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAK 1047

Query: 1185 ----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDT 1239
                C+A LTV         RL E + V     A    +I       VTW      +E++
Sbjct: 1048 DELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEES 1107

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEY 1266
            E   L  D    +L I     +D+  Y
Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLY 1134



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E + AP F   +       G T +F   VEG P P I W++   ++  S      Y ++N
Sbjct: 1480 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVY-EEN 1538

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
              +LV+     +D G +TC A+N AG  S   EL V +
Sbjct: 1539 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 1576



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 16/156 (10%)

Query: 780  TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839
            ++ D D + + I +  + +D G  T  A N  G  +T +V      T E AE P F +  
Sbjct: 1440 SQPDDDQYCLRICRVSR-RDMGALTCTARNRHG-TQTCSV------TLELAEAPRFESIM 1491

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
            +++ V    T +    V   P+P I WY++  +++ S  ++  ++     LV+ +  ++ 
Sbjct: 1492 EDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQ- 1550

Query: 900  DSGDYKCVASNSAGKSS-------HGARVTIDVEKV 928
            D G Y C A N AG+ S       H A+  ++VE V
Sbjct: 1551 DGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGV 1586



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 29/101 (28%), Positives = 54/101 (53%), Gaps = 6/101 (5%)

Query: 727 IKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTK 781
           +  GE+  E P    PL++++V  G  V+L   +  NP P ++W K+   +++   L  +
Sbjct: 712 VSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLR 771

Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
           ++G+ H++ +L+  +  D G Y   A N  G A  +A +TV
Sbjct: 772 AEGERHTL-LLREARAADAGSYMATATNELGQATCAASLTV 811



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 36/175 (20%), Positives = 78/175 (44%), Gaps = 6/175 (3%)

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
            E ++   + G+P P + W+ NG+++++  +  +T       +    +   H+  Y    +
Sbjct: 1204 EAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIA 1263

Query: 1649 NTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPP--LDDG-GLELTKYAIE 1704
            N  G ++    L V D  P  P+G   +  ++   VT+ W PP  LD     +   Y ++
Sbjct: 1264 NKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQ 1323

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758
                 +++W  +    R+   +    L +  +++FRV++      S+ +  SEP+
Sbjct: 1324 HQVLGSDQWTALVTGLRE-PGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPV 1377



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 19/62 (30%), Positives = 34/62 (54%)

Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
            +   + + Y    E  +++P  E PL+N+   P  D+ L CI    P P+V+W++DG  L
Sbjct: 703  ELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSAL 762

Query: 1523 KT 1524
            ++
Sbjct: 763  RS 764



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 64/280 (22%), Positives = 102/280 (36%), Gaps = 19/280 (6%)

Query: 552  PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611
            P +   M  D D++   V  +V   D  T         G+A++     V+       +  
Sbjct: 1305 PPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLST-- 1362

Query: 612  TVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666
            TV              +LE  P     P    KP   YV EG    +      + E  + 
Sbjct: 1363 TVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHV-EAQVV 1421

Query: 667  WLF-KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725
            W   +G  +     +    + D   YC  L+I  V +   G  T  A NR G  +  + L
Sbjct: 1422 WRSCRGALLEARAGVYELSQPDDDQYC--LRICRVSRRDMGALTCTARNRHGTQTCSVTL 1479

Query: 726  KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--- 782
            ++     E P+    ++ + V  GE+   +  V G P P I W K+   +      S   
Sbjct: 1480 ELA----EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVY 1535

Query: 783  DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
            + +  S+ +L     +D GVYT  A+N  G     A + V
Sbjct: 1536 EENECSLVVLS-TGAQDGGVYTCTAQNLAGEVSCKAELAV 1574



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%)

Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER-DGEIIKPKKNKYDFEKRGHIR 1072
            E  P  + K     V E   A + V  N   A VVW    G +++ +   Y+  +    +
Sbjct: 1387 EEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQ 1446

Query: 1073 K-LYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127
              L I   S  D G  +C  R+    ++C+  + + E P    + +++ +V  G  A F 
Sbjct: 1447 YCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAP-RFESIMEDVEVGAGETARFA 1505

Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            + + +G  L  + W+KD   +  S+H+    +  +  L +      D G Y+C   N
Sbjct: 1506 V-VVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQN 1561



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 61/278 (21%), Positives = 103/278 (37%), Gaps = 14/278 (5%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQ-FSNHIQLTIDGKKQKL 1163
            PP     L +Q V +G      I +  +   +V W ++   ++          +G   +L
Sbjct: 868  PPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRL 927

Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTVEE--PSINFTLRLP-EFILVPANTDAYL 1216
            +I   +  DAG Y+C    E G  +C A L V     S +  +  P + + V A   A  
Sbjct: 928  RILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALF 987

Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
               +   T ++V W  +  +++    K  +  D +K  L++    EDD   YTC L  AK
Sbjct: 988  ECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAK 1047

Query: 1275 STTKLKVEVVEFP---PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
                    +   P   P       +  +  G            P P   W      +++ 
Sbjct: 1048 DELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEES 1107

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
            ++ +   D    SL I  V + D G+Y +   N  G A
Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQA 1145



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 7/116 (6%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
           P  + PLK+  V  G  V L   V G P P + W ++    + LP  +     S   L+ 
Sbjct: 43  PVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDG---QLLP--APAPEPSCLWLRR 97

Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITV-EEPTEENAEPPLF-INRFQEITVKEKG 848
              +D GVY+  A+N  G A   AV+TV E    E AE  +  +   Q + +++ G
Sbjct: 98  CGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDG 153



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 1/108 (0%)

Query: 496 PVFEKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554
           P   + +S+  S AP  F   L  +   +G  V    +V+G P+P ++W R    ++P Q
Sbjct: 854 PSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQ 913

Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
                  +  +  L I      DAG +TC A N  G       L V A
Sbjct: 914 RRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRA 961



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 6/150 (4%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            P P + W K+   L ++    I + K+   ++ I    + H+  Y   A+N  G+ +   
Sbjct: 2611 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718
            T+ V   P K   P +  +  +++  + WKP   D     T Y +E+     + W  V+ 
Sbjct: 2671 TVAVARVPGKLAPPEV-TQTYQDTALVLWKP--GDSRAPCT-YTLERRVDGESVWHPVSS 2726

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
               D   Y +  L       FRV   N  G
Sbjct: 2727 GIPDC-YYNVTHLPVGVTVRFRVACANRAG 2755



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP+F+  L+      GS V+    V G P P + WFR   ++ P+            + L
Sbjct: 42  APVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDGQLL-PA-------PAPEPSCL 93

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +R    +DAG ++C+A+N  G AS    L V
Sbjct: 94  WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 18/76 (23%), Positives = 40/76 (52%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G + L+  +I   PPP+V W+K+G+ L ++    +  + +   + ++E + + +  Y   
Sbjct: 736  GADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMAT 795

Query: 1647 ASNTAGTSSVEVTLKV 1662
            A+N  G ++   +L V
Sbjct: 796  ATNELGQATCAASLTV 811



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 3/100 (3%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540
            +P   +PLKN       D+ L  +  G P P + W+RDG+ L    A             
Sbjct: 42   APVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDGQLL---PAPAPEPSCLWLRRC 98

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
                   Y C+A N+ G      V+ + +      + +DI
Sbjct: 99   GAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDI 138



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 46/226 (20%), Positives = 76/226 (33%), Gaps = 9/226 (3%)

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
            Y    V+   A +     +V    + +S  V  PL+++     E     C+  G    +V
Sbjct: 940  YTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEV 999

Query: 1514 TWYRDGKKLKTA----KATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
             W   G+ L+ A    K  ++ R                Y C       E+  S  + ++
Sbjct: 1000 DWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVR 1059

Query: 1569 QK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626
                P+ T   ED++     G        I G PPP V W   G  +E  +   +     
Sbjct: 1060 PSLAPLFTRLLEDVEVLE--GRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGG 1117

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
               + I  +       Y + A NT G +     L V +  +   GP
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP 1163



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 1113 LQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
            LQN  V  G     +  +T      V W KDGS ++    + L  +G++  L + +    
Sbjct: 728  LQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAA 787

Query: 1172 DAGEYSC----EVGNSKCTAILTV 1191
            DAG Y      E+G + C A LTV
Sbjct: 788  DAGSYMATATNELGQATCAASLTV 811



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 13/191 (6%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344
            +FPP      ++  +  G   TLL    A P P+  W+ +    KK   ++PS+   S  
Sbjct: 2581 DFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD----KKSLRSEPSVIIVSCK 2636

Query: 1345 -----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
                 L+I +     AG+Y+    N  G       V +   P     P + +    +  +
Sbjct: 2637 DGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQTYQDTALV 2696

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             W   ++    T   Y +E +    + W  V + I     ++ +L    + RFR    N 
Sbjct: 2697 LWKPGDSRAPCT---YTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANR 2753

Query: 1459 VDISDASETTE 1469
                  S ++E
Sbjct: 2754 AGQGPFSNSSE 2764



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 5/109 (4%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP F  K K Q + EG    L C   A P P I+W+   + +  + ++ +    D     
Sbjct: 2583 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR--- 2639

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIE 739
             +L I    K   G Y   A N  G   +S  + +    G+  PP+V +
Sbjct: 2640 QLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQ 2688



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 24/100 (24%), Positives = 35/100 (35%), Gaps = 1/100 (1%)

Query: 505  EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564
            E    P+F  KL+ +   +G      C     P P I+W +    ++      +    D 
Sbjct: 2579 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDG 2638

Query: 565  VATLVIREVFPEDAGTFTCVAKNAAG-FASSTTELIVEAP 603
               L I       AG + C A N  G   SS T  +   P
Sbjct: 2639 RQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 22/95 (23%), Positives = 36/95 (37%), Gaps = 5/95 (5%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXX 1536
            P     LK+      E   L C+    P P ++W +D K L++  +       + R    
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
                       Y+C A N  G + +SC V + + P
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 4/111 (3%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSIT 790
            PP     LK  ++ +GE+  L       P P I+W K+ K +++ P+    S  D   + 
Sbjct: 2583 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLL 2642

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841
             +     +  G+Y   A N  G   +S  + V     + A PP     +Q+
Sbjct: 2643 SIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLA-PPEVTQTYQD 2692


>UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|Rep:
            Neogenin precursor - Mus musculus (Mouse)
          Length = 1493

 Score =  103 bits (247), Expect = 5e-20
 Identities = 137/592 (23%), Positives = 226/592 (38%), Gaps = 57/592 (9%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            L C+  G+P P V W ++ + L T    +                     Y CIA N + 
Sbjct: 279  LPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNK 338

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
             VE    + +Q  P       +I     +  + +    + G P P V W KNG+ +    
Sbjct: 339  TVEAQAELTVQVPPGFLKQPANIYAHESM--DIVFECEVTGKPTPTVKWVKNGDVVIPSD 396

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK----PSKPE--- 1670
             + I  +    V+    L +S    Y   A N  G +     L + +     P+ P    
Sbjct: 397  NFKIVKEHNLQVLG---LVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSL 453

Query: 1671 -------------GP-------VIMREISRESVTIEWKPPLDDG-GLELTKYAIEKHEPD 1709
                         GP       V+   +S   + + W+ P  D  G  LT       E  
Sbjct: 454  TSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGV 513

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP-S 1768
            +   ++      +++   IQ L     Y+F+V+AQN  G  E+  S P+ ++T  +V   
Sbjct: 514  DRERVENTSQPGEMQV-TIQNLMPATVYIFKVMAQNKHGSGES--SAPLRVETQPEVQLP 570

Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQK 1828
                          S+ +TW  +  +G   I +YK+   ++G   +           I  
Sbjct: 571  GPAPNIRAYATSPTSITVTW-ETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTING 629

Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTSRSVTLKW 1886
            L   T Y FR+ A N+ G   P  S   + + +TL+  P + P+N  +    S+S+ + W
Sbjct: 630  LKKYTEYSFRVVAYNKHG---PGVSTQDVAV-RTLSDVPSAAPQNLSLEVRNSKSIVIHW 685

Query: 1887 TEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945
              P S      IT Y I ++    KS      V G+     IE +    E  FR++A   
Sbjct: 686  QPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTV 745

Query: 1946 VGVSLPTESQSVRLEK----HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
             G    T+  S    +       VP  P++ L +R + ++IV+ SW  PE +    + GY
Sbjct: 746  NGTGPATDWLSAETFESDLDETRVPEVPSS-LHVRPLVTSIVV-SWTPPE-NQNIVVRGY 802

Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
              AI     +   +  KVD     + I +L  +  Y+I + A N +G   PL
Sbjct: 803  --AIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPL 852



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 79/326 (24%), Positives = 130/326 (39%), Gaps = 21/326 (6%)

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS-KPEGP---VIMREISRESVTIEWKPPLDDGGLEL 1698
            + + A N  G+      L+V  +P  +  GP   +     S  S+T+ W+ PL   G E+
Sbjct: 542  FKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNG-EI 600

Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
              Y +   E   +   K  D+D    +Y I  L +  EY FRV+A N  G    + ++ +
Sbjct: 601  QNYKLYYMEKGTD---KEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHG--PGVSTQDV 655

Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEGKK---WK 1814
             ++T  DVPS           +++S+ I W  PS       I  YK+  ++  +K    +
Sbjct: 656  AVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTE 715

Query: 1815 XXXXXXXXXARIQKLSINTTYQFRIYAR--NEIGTSLPYTSDDKITIGKTLT-PPSQPRN 1871
                       I+ L   T Y FR+ A   N  G +  + S +        T  P  P +
Sbjct: 716  TLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSS 775

Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931
              V    + S+ + WT PE N    +  Y I +    G    + + V      + IEN+ 
Sbjct: 776  LHVRPLVT-SIVVSWTPPE-NQNIVVRGYAIGYGI--GSPHAQTIKVDYKQRYYTIENLD 831

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSV 1957
                 +  + A N VG  +P    +V
Sbjct: 832  PSSHYVITLKAFNNVGEGIPLYESAV 857



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 78/299 (26%), Positives = 131/299 (43%), Gaps = 32/299 (10%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F+ +P+   V  G+  +L C + A   P + W    + ++ D+ I V + S       
Sbjct: 163 PRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRI-VKLPS------G 215

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-----KSMIVRQ 748
            L I+N  +   G Y  + V   G        ++K  + +P ++++ +      SM+   
Sbjct: 216 TLVISNATEGDGGLYRCI-VESGGPPKFSDEAELKVLQ-DPEEIVDLVFLMRPSSMMKVT 273

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVK--DEGVYT 804
           G+S +L   V G P P + W KN +    L T+S G    +    L+   V   D G Y 
Sbjct: 274 GQSAVLPCVVSGLPAPVVRWMKNEE---VLDTESSGRLVLLAGGCLEISDVTEDDAGTYF 330

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A+N     E  A +TV+ P       P F+ +   I   E   I     VT  P P++
Sbjct: 331 CIADNGNKTVEAQAELTVQVP-------PGFLKQPANIYAHESMDIVFECEVTGKPTPTV 383

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W +N +++ PS+   +     N++ V+  V S  D G Y+C+A N  G +  GA++ I
Sbjct: 384 KWVKNGDVVIPSDNF-KIVKEHNLQ-VLGLVKS--DEGFYQCIAENDVGNAQAGAQLII 438



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 203/1021 (19%), Positives = 357/1021 (34%), Gaps = 112/1021 (10%)

Query: 1035 ILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT--SVH---DEGEYS 1088
            IL     SE + ++ W++DG  +  + +  D  +      L+I N   S H   DEG Y 
Sbjct: 82   ILNCSAYSEPSPNIEWKKDGTFLNLESD--DRRQLLPDGSLFISNVVHSKHNKPDEGFYQ 139

Query: 1089 CILRDE------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFK 1141
            C+   +      S TA++TV  LP    ++ +   V  GN A    E+       VRW +
Sbjct: 140  CVATVDNLGTIVSRTAKLTVAGLP-RFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQ 198

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPS 1195
            +   +   + I     G    L I +    D G Y C V +      S    +  +++P 
Sbjct: 199  NRQPLLLDDRIVKLPSGT---LVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPE 255

Query: 1196 ----INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
                + F +R P  ++      A L   +      V  + K   + DTE    +  +   
Sbjct: 256  EIVDLVFLMR-PSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGG 314

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310
             L I   TEDD   Y C+  +   T + + E+ V+ PP  +            D+    +
Sbjct: 315  CLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECE 374

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK-------------VENTDAGI 1357
                P P  +W+ N  ++    + K   +     L + K             V N  AG 
Sbjct: 375  VTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGA 434

Query: 1358 YKLRLENNCG----------HADVEMNVTILDKPSPPGKPNILE--IDSSSINICWDEPE 1405
              + LE++             A  +        P P    +++   + +  I + W  P 
Sbjct: 435  QLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPA 494

Query: 1406 NTGNSTIIYYVVEYQE--IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463
            +  +   + Y V Y +  +D     +     + Q +IQNL   + Y F+  A N+     
Sbjct: 495  SDPHGDNLTYSVFYTKEGVDRERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNK---HG 551

Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKK 1521
            + E++   +V  + ++Q P     ++   T P        T + G         Y   K 
Sbjct: 552  SGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKG 611

Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVV--GIQQKPVITISNE 1578
                +    +                ++ +A+N HG  V T  V    +   P     N 
Sbjct: 612  TDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNL 671

Query: 1579 --DIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
              +++    +   W    +    G      I Y+  ++  +  E  +T  + + +I  + 
Sbjct: 672  SLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLI--EG 729

Query: 1635 LKRSHSSKYTIEASNTAGTS------SVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEW 1687
            L R     + + A    GT       S E      D+   PE P  +       S+ + W
Sbjct: 730  LDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSW 789

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
             PP ++  + +  YAI       +   +   VD     Y I+ L+ +  Y+  + A N V
Sbjct: 790  TPP-ENQNIVVRGYAIGYGIGSPHA--QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNV 846

Query: 1748 G----FSEALESEPIVIKTALDV--------------PSXXXXXXXXXXIDNESVYITWF 1789
            G      E+  + P    + +D+              P           + ++++ ITW 
Sbjct: 847  GEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWA 906

Query: 1790 PSEKNGGSPIID---YKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
             +       I D   Y V  K       K+K           +  L  NT Y+F +    
Sbjct: 907  DNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYL-VTGLKPNTLYEFSVMVTK 965

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
               +S    +    T     T P +    V  E   R++ + W +P S     IT YII 
Sbjct: 966  GRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNW-QPPSEANGKITGYIIY 1024

Query: 1904 FKT---VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
            + T    +   W  I  V G+   H I+ +       F+I A N+ G+   +E+   R  
Sbjct: 1025 YSTDVNAEIHDWV-IEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTP 1083

Query: 1961 K 1961
            K
Sbjct: 1084 K 1084



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 95/384 (24%), Positives = 161/384 (41%), Gaps = 40/384 (10%)

Query: 737  VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-----NNKPVKALPTKSDGDTHSITI 791
            ++EP+ ++ VR G SVIL+      P P I W K     N +         DG      +
Sbjct: 67   LVEPVDTLSVR-GSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNV 125

Query: 792  LKPKKVK-DEGVYTLKA--ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
            +  K  K DEG Y   A  +N   I   +A +TV       A  P F ++ +  +V    
Sbjct: 126  VHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTV-------AGLPRFTSQPEPSSVYVGN 178

Query: 849  TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-V 907
            +  L   V  + VP + W +N + +   + I +   G    LVI+N  +E D G Y+C V
Sbjct: 179  SAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSG---TLVISNA-TEGDGGLYRCIV 234

Query: 908  ASNSAGKSSHGARVTI--DVEKVTFVKHLQK--SYETEEGKTVILECQTSHTVS--TKWY 961
             S    K S  A + +  D E++  +  L +  S     G++ +L C  S   +   +W 
Sbjct: 235  ESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWM 294

Query: 962  HNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV----KDQETSTMLVVKETI 1016
             N++ + +    R ++  G             D G   CI     K  E    L V +  
Sbjct: 295  KNEEVLDTESSGRLVLLAG--GCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTV-QVP 351

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F+++  +    E    + E E+  + T  V W ++G+++ P  N +   K  +++ L 
Sbjct: 352  PGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDN-FKIVKEHNLQVLG 410

Query: 1076 IRNTSVHDEGEYSCILRDESCTAE 1099
            +  +   DEG Y CI  ++   A+
Sbjct: 411  LVKS---DEGFYQCIAENDVGNAQ 431



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           F  +P +     G   +L C +  +P P + W+ K EE++  E+    +     +    L
Sbjct: 262 FLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWM-KNEEVLDTESSGRLVL----LAGGCL 316

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
           +I++V +   GTY  +A N          L ++     PP  ++   ++   +   ++  
Sbjct: 317 EISDVTEDDAGTYFCIADNGNKTVEAQAELTVQV----PPGFLKQPANIYAHESMDIVFE 372

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            +V G P PT+ W KN   V           H++ +L   K  DEG Y   AEN  G A+
Sbjct: 373 CEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQVLGLVK-SDEGFYQCIAENDVGNAQ 431

Query: 816 TSAVITVEE 824
             A + + E
Sbjct: 432 AGAQLIILE 440



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 80/336 (23%), Positives = 139/336 (41%), Gaps = 15/336 (4%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           GS ++L C   + P P+I W   G  +  + +    +  D  ++ S +  +   K  EG 
Sbjct: 78  GSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGF 137

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           Y  VA        +    K+ T    P    +P  S  V  G S IL+ +V  +  P + 
Sbjct: 138 YQCVATVDNLGTIVSRTAKL-TVAGLPRFTSQPEPSS-VYVGNSAILNCEVNADLVPFVR 195

Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS--AVITVEEP 825
           W +N +P+  L  +         ++      D G+Y    E S G  + S  A + V + 
Sbjct: 196 WEQNRQPL-LLDDRIVKLPSGTLVISNATEGDGGLYRCIVE-SGGPPKFSDEAELKVLQD 253

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFD 884
            EE  +    +     + V  +  + L   V+  P P + W +N E++ + S        
Sbjct: 254 PEEIVDLVFLMRPSSMMKVTGQSAV-LPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLA 312

Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
           G  +E  I++V +E D+G Y C+A N        A +T+ V    F+K     Y   E  
Sbjct: 313 GGCLE--ISDV-TEDDAGTYFCIADNGNKTVEAQAELTVQVPP-GFLKQPANIY-AHESM 367

Query: 945 TVILECQTS--HTVSTKWYHNKKEISGMDHREIIQE 978
            ++ EC+ +   T + KW  N   +   D+ +I++E
Sbjct: 368 DIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKE 403



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 62/297 (20%), Positives = 108/297 (36%), Gaps = 39/297 (13%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G +    C V G P P + W +   ++      ++         L I +V  +DAGT+ C
Sbjct: 274 GQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGC--LEISDVTEDDAGTYFC 331

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
                               ++D+G++ TV            A++   +PP F K+P   
Sbjct: 332 --------------------IADNGNK-TVEAQ---------AELTVQVPPGFLKQPANI 361

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
           Y  E  DI+ EC +   P P + W+  G+ ++P +N  +  E +       L++  + K 
Sbjct: 362 YAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHN-------LQVLGLVKS 414

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
            EG Y  +A N  G A     L I   +   P +     +       +   +  +   PR
Sbjct: 415 DEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPR 474

Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
             +    + + +K        D H   +        EGV   + EN+    E    I
Sbjct: 475 DVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVDRERVENTSQPGEMQVTI 531



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 4/91 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++    +  +   + FEC+V G P P + W +   ++ PS +F++  + +    L 
Sbjct: 352 PGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHN----LQ 407

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           +  +   D G + C+A+N  G A +  +LI+
Sbjct: 408 VLGLVKSDEGFYQCIAENDVGNAQAGAQLII 438


>UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout
            homolog 2; n=2; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to roundabout homolog 2 -
            Strongylocentrotus purpuratus
          Length = 1809

 Score =  103 bits (246), Expect = 7e-20
 Identities = 128/534 (23%), Positives = 212/534 (39%), Gaps = 54/534 (10%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-DTHSI 789
            E+  P + E  KS+IV +G+    + +  G P PTI+W KN +P+    T+    D+ S+
Sbjct: 18   EESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSL 77

Query: 790  TILK----PKKVKDEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEITV 844
              L+     +  +D GVY   A NS G A   +A + +    E+  E P+      +  +
Sbjct: 78   FFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPV-----SDQLI 132

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
                 +         P P +TW ++++ I       +  +  N+ L     D   D G Y
Sbjct: 133  SGDSAVLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELRKD---DEGTY 189

Query: 905  KCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWY 961
            KC A N AG + S  A +T+ V K  F+   Q +  T  G+  +L C+       +  W 
Sbjct: 190  KCKAQNVAGERISKDAYLTVQV-KPAFINPPQDTI-TAPGEAAVLRCEVEGDPPPTVSWS 247

Query: 962  HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIP 1017
                E+   D R   Q+              D GV  C  ++     +    L V   +P
Sbjct: 248  REIGELP--DGR--TQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRV-SAVP 302

Query: 1018 EFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGE-----IIKPKKNKYDFEKRGHI 1071
            +FIR  +D  V   ++   + E + S    + W++ G       I  ++ +++    G  
Sbjct: 303  DFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASG-- 360

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTVV--------ELPPEIITRLQNQKVNKGNK 1123
             +L I    + D G Y C     +  AE   V          PP I     NQ +  G+ 
Sbjct: 361  -ELQINPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGST 419

Query: 1124 ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            ATF        +  + W KDG  +  SN  + ++      L+I    +DD+G YSC   +
Sbjct: 420  ATFMCRSAGNPSPQIEWTKDGIALTTSNP-RFSLMYPDNTLEITGVQVDDSGLYSCLASS 478

Query: 1183 -----SKCTAILTVE--EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
                 S+   +L +E  E S       P    +P +    L V +   ++ V W
Sbjct: 479  NSGETSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRW 532



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 78/293 (26%), Positives = 127/293 (43%), Gaps = 19/293 (6%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           PT +++PK+  V  G      C+    PEP I+WL  G+ +V  +     ++S    +  
Sbjct: 22  PTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSLFFLQ 81

Query: 694 VLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
           V  + N +  Q+ G Y  +A N  G A S    L+I    ++  +  EP+   ++    +
Sbjct: 82  V--VGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFRE--EPVSDQLISGDSA 137

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           V+      G P P +TW K+++P+     +         +LK  +  DEG Y  KA+N  
Sbjct: 138 VLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELRKDDEGTYKCKAQNVA 197

Query: 812 G-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
           G      A +TV+         P FIN  Q+          L   V  +P P+++W R  
Sbjct: 198 GERISKDAYLTVQ-------VKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSR-- 248

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           EI    +  TQ     ++ +  T+   E+D G Y C A N  G S   AR+ +
Sbjct: 249 EIGELPDGRTQQLPDNSLRIRHTD---ELDDGVYICTAENIWGTSDAKARLRV 298



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 102/425 (24%), Positives = 169/425 (39%), Gaps = 53/425 (12%)

Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKP 552
           L  F  P    +  AP   E+ +      G    F C+ EG P P I+W +  Q  +I+ 
Sbjct: 7   LATFVSPGRRTEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRD 66

Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612
           ++   +         +V      +D G + C+A N+ G A S    +  A L +   E  
Sbjct: 67  TRHTVLDSGSLFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEP 126

Query: 613 VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672
           V              +LE  PP     P+  ++ +   I+L+   V              
Sbjct: 127 VSDQLISGDSA----VLECTPPRGYPTPEVTWLKDDQPIILDNNRV-------------- 168

Query: 673 EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGE 731
           +IV D N+             +LK   ++K  EGTY   A N  GE  S    L ++   
Sbjct: 169 KIVEDGNL-------------LLK--ELRKDDEGTYKCKAQNVAGERISKDAYLTVQV-- 211

Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
              P  I P +  I   GE+ +L  +V G+P PT++W +    +    T+   D +S+ I
Sbjct: 212 --KPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREIGELPDGRTQQLPD-NSLRI 268

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
               ++ D+GVY   AEN  G ++  A + V       +  P FI   ++ TV     ++
Sbjct: 269 RHTDEL-DDGVYICTAENIWGTSDAKARLRV-------SAVPDFIRAPRDKTVHVNEMVR 320

Query: 852 LVARVTRNPVPSITWYR---NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908
                  +P PSI W +    + ++  ++   +     + EL I  V  + D+G Y C A
Sbjct: 321 FQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMD-DAGTYICYA 379

Query: 909 SNSAG 913
           +   G
Sbjct: 380 TGGTG 384



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 71/298 (23%), Positives = 118/298 (39%), Gaps = 23/298 (7%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           + P F   P+      G   +L C +   P P ++W  +  E+ PD       ++     
Sbjct: 211 VKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREIGEL-PDGRTQQLPDNS---- 265

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              L+I +  +  +G Y   A N  G +     L++       P  I   +   V   E 
Sbjct: 266 ---LRIRHTDELDDGVYICTAENIWGTSDAKARLRVSA----VPDFIRAPRDKTVHVNEM 318

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-----LKPKKVKDEGVYTLK 806
           V    + VG+P P+I W K       L          ++      + P ++ D G Y   
Sbjct: 319 VRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTYICY 378

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
           A    G+AE  AV+ V +  E  A PPL        T+    T   + R   NP P I W
Sbjct: 379 ATGGTGVAEAKAVLRVLD--ESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQIEW 436

Query: 867 YRNNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ++   ++ S    +  +    +E+    VD   DSG Y C+AS+++G++S  A + +
Sbjct: 437 TKDGIALTTSNPRFSLMYPDNTLEITGVQVD---DSGLYSCLASSNSGETSQSATLLV 491



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 73/298 (24%), Positives = 114/298 (38%), Gaps = 24/298 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F + P+ + V     +  +C  V  P P I W   G E    +N+    +       S
Sbjct: 302 PDFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTE----DNLLFINQQRGRFEVS 357

Query: 694 V---LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQ 748
               L+I  V+    GTY   A    G A    VL++      PP +I+  P    +V  
Sbjct: 358 ASGELQINPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLV-V 416

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           G +     +  GNP P I W K+   +  + P  S     +   +   +V D G+Y+  A
Sbjct: 417 GSTATFMCRSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLA 476

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARVT--------- 857
            ++ G    SA + V E TE +  P        E+       +++ V R +         
Sbjct: 477 SSNSGETSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPA 536

Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV--ASNSAG 913
            N  PS+T Y+  E  SP         G  I+    N++  + S  +  V  A NS G
Sbjct: 537 ANRAPSVTGYQ-VEYFSPERVTGWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNG 593



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 110/512 (21%), Positives = 189/512 (36%), Gaps = 55/512 (10%)

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEV 1100
            T +V W +D + I    N+    + G+   L ++     DEG Y C  ++   E  + + 
Sbjct: 149  TPEVTWLKDDQPIILDNNRVKIVEDGN---LLLKELRKDDEGTYKCKAQNVAGERISKDA 205

Query: 1101 TV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTID 1157
             + V++ P  I   Q+     G  A    E+ +GD    V W ++  E+      QL   
Sbjct: 206  YLTVQVKPAFINPPQDTITAPGEAAVLRCEV-EGDPPPTVSWSREIGELPDGRTQQLP-- 262

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213
                 L+I   D  D G Y C      G S   A L V   ++   +R P    V  N  
Sbjct: 263  --DNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVS--AVPDFIRAPRDKTVHVNEM 318

Query: 1214 AYLTVE-IPDETLDVTWYK---KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                 E +      + W K   + +++   ++           L I     DD   Y C 
Sbjct: 319  VRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTYICY 378

Query: 1270 ------LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
                  + +AK+  ++  E +  PP I        +  GS  T +      P P  EW  
Sbjct: 379  ATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQIEWTK 438

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--- 1380
            +  I     + + S+     +L I  V+  D+G+Y     +N G       + +++    
Sbjct: 439  DG-IALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSATLLVIESTET 497

Query: 1381 --------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID-TT 1425
                          P  P +P  + +  SSI + W  P      ++  Y VEY   +  T
Sbjct: 498  SGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQVEYFSPERVT 557

Query: 1426 EWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
             W+   N  + +T +I +L  +SS+     A+N   I      +E     +ET    P+ 
Sbjct: 558  GWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNGIGPPGPMSESISTSEETANPPPSR 617

Query: 1485 EKPLKNITTEPNEDIELTCIFG-GVPQPKVTW 1515
            E     ++ + +  +E+T I        KV+W
Sbjct: 618  E----CLSDQSSITVEITTIIALSSTAIKVSW 645



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 79/414 (19%), Positives = 154/414 (37%), Gaps = 29/414 (7%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK--IIKKCKHTKPSIDSKS 1342
            E  P I +  +   + RG   +     +  P+P   W+ N +  +I+  +HT   +DS S
Sbjct: 19   ESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTV--LDSGS 76

Query: 1343 A---SLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTIL--DKPSPPGKPNILEIDS 1394
                 +   +    D G+Y+    N+ G    A+  + +  L  D    P    ++  DS
Sbjct: 77   LFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDS 136

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
            + +  C   P     +  + ++ + Q I   +   VK +      ++ L+ +    ++  
Sbjct: 137  AVLE-C--TPPRGYPTPEVTWLKDDQPI-ILDNNRVKIVEDGNLLLKELRKDDEGTYKCK 192

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            A N   ++    + + Y  ++      P    P ++  T P E   L C   G P P V+
Sbjct: 193  AQN---VAGERISKDAYLTVQV----KPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVS 245

Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
            W R+  +L   +                     Y C A N  G  +    + +   P   
Sbjct: 246  WSREIGELPDGRTQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFI 305

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG---NKLENDKEYNITTKEKTSVIR 1631
             +  D K  H V +         G PPP + W K G   N L  +++        +  ++
Sbjct: 306  RAPRD-KTVH-VNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQ 363

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            I  ++   +  Y   A+   G +  +  L+V D+   P  P+I    + +++ +
Sbjct: 364  INPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPP-PLIQYGPANQTLVV 416



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 5/81 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           GST  F C+  G P PQI W +   A+   +  F + Y D+   TL I  V  +D+G ++
Sbjct: 417 GSTATFMCRSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDN---TLEITGVQVDDSGLYS 473

Query: 583 CVAKNAAGFAS-STTELIVEA 602
           C+A + +G  S S T L++E+
Sbjct: 474 CLASSNSGETSQSATLLVIES 494



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 97/473 (20%), Positives = 169/473 (35%), Gaps = 60/473 (12%)

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-D 1370
            + +P P   W+ + + I    +    ++    +L +K++   D G YK + +N  G    
Sbjct: 145  RGYPTPEVTWLKDDQPIILDNNRVKIVED--GNLLLKELRKDDEGTYKCKAQNVAGERIS 202

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-S 1429
             +  +T+  KP+              IN   D     G + ++   VE     T  W   
Sbjct: 203  KDAYLTVQVKPA-------------FINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSRE 249

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-----PTV 1484
            +  +   +T  Q L  NS    R    +E+D      T E      + K +      P  
Sbjct: 250  IGELPDGRT--QQLPDNS---LRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDF 304

Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK-----LKTAKATYENRXXXXXXX 1539
             +  ++ T   NE +   C   G P P + W + G +     +   +  +E         
Sbjct: 305  IRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQI 364

Query: 1540 X--XXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLVTA 1594
                      Y C A    G  E   V+ +  +   P   I      Q   VG       
Sbjct: 365  NPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMC 424

Query: 1595 VIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653
               G P P++ W K+G  L  ++  +++   + T  + I  ++   S  Y+  AS+ +G 
Sbjct: 425  RSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDNT--LEITGVQVDDSGLYSCLASSNSGE 482

Query: 1654 SSVEVTLKVYDK-----------------PSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696
            +S   TL V +                  P  P  P+ +  ++R S+ + W  P  +   
Sbjct: 483  TSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVN-VTRSSIQVRWTAPAANRAP 541

Query: 1697 ELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
             +T Y +E   P+    W+ VA      ETY I  L  +  ++  V A N  G
Sbjct: 542  SVTGYQVEYFSPERVTGWV-VAGNGIQGETYNINHLVPSSSHLVVVRAINSNG 593



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 80/395 (20%), Positives = 142/395 (35%), Gaps = 34/395 (8%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHI 1071
            +E+ P    + +   V   D A    +        + W ++G+ +  +  ++     G +
Sbjct: 18   EESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSL 77

Query: 1072 RKLYI--RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
              L +        D G Y C+  +      S  A + +  L  +      + ++  G+ A
Sbjct: 78   FFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDSA 137

Query: 1125 TFEIELTKGDAL--VRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181
              E    +G     V W KD   I   N+ +++  DG    L + +   DD G Y C+  
Sbjct: 138  VLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGN---LLLKELRKDDEGTYKCKAQ 194

Query: 1182 N------SKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKK 1233
            N      SK  A LTV+ +P+    +  P+  +      A L  E+  D    V+W ++ 
Sbjct: 195  NVAGERISK-DAYLTVQVKPAF---INPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREI 250

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVD 1292
              + D         +   +L IR   E D   Y C   +   T+  K  + V   P  + 
Sbjct: 251  GELPDGRT----QQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFIR 306

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWI---VNSKIIKKCKHTKPSIDSKSASLTIKK 1349
              R+  +     V    +    P P+  W        ++   +       S S  L I  
Sbjct: 307  APRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINP 366

Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
            V+  DAG Y        G A+ +  + +LD+   P
Sbjct: 367  VQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAP 401



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 15/170 (8%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKR--SHSSKY 1643
            GD        EG P P + W KNG  L   D  + +        +++   ++       Y
Sbjct: 36   GDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSLFFLQVVGNRQGGQDGGVY 95

Query: 1644 TIEASNTAGTS-SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701
               A N+ GT+ S   TL++ Y +    E PV  + IS +S  +E  PP      E+T  
Sbjct: 96   QCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDSAVLECTPPRGYPTPEVT-- 153

Query: 1702 AIEKHEP---DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
             ++  +P   DNNR +K+ + D ++    +++L ++ E  ++  AQN  G
Sbjct: 154  WLKDDQPIILDNNR-VKIVE-DGNL---LLKELRKDDEGTYKCKAQNVAG 198



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR---QTAIIKPSQDFQMYYDDD 563
           S  P F+   R K       V+F+C+  G P P I W +   +  ++  +Q  +  ++  
Sbjct: 299 SAVPDFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQ-RGRFEVS 357

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
               L I  V  +DAGT+ C A    G A +   L V
Sbjct: 358 ASGELQINPVQMDDAGTYICYATGGTGVAEAKAVLRV 394


>UniRef50_Q4SK53 Cluster: Chromosome 2 SCAF14570, whole genome shotgun
            sequence; n=4; Euteleostomi|Rep: Chromosome 2 SCAF14570,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 1792

 Score =  103 bits (246), Expect = 7e-20
 Identities = 86/383 (22%), Positives = 146/383 (38%), Gaps = 17/383 (4%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
            G +  L       P P   W  N K I+  +  K +      SL I+ V +   G+YK  
Sbjct: 223  GKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSVRHAHGGVYKSV 282

Query: 1362 LENNCGHADVEMNVTILD-KPSPP-GKPNILEIDSSSINICWDEPENTGNS---TIIYYV 1416
            + N  G A    ++ + D  P PP G P I  I   +I + W +P+    S   + + Y 
Sbjct: 283  ISNKVGKATCYAHLYVTDILPDPPDGTPVIESITGKTITLSWKKPKRLDPSIDPSSLMYA 342

Query: 1417 VEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475
            ++ Q + + +W I    +  T  +I +L     Y FR   +     S  S  T+  +++ 
Sbjct: 343  IQQQSLGSIQWTIIASGLKDTMYTISSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLLD 402

Query: 1476 ETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--- 1530
                  ++P +    + +    N+ + +T     V    V W R G  L +    YE   
Sbjct: 403  RGPYLQEAPIIVDKPEIVYVIENQSVTITITLNHV-NAAVLWKRKGVILASKPGVYEMSM 461

Query: 1531 ---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
               ++                  +A N HG    +  V +   P      ED+      G
Sbjct: 462  PDDDQHTLKLFKVKSDDIGEMTFMASNKHGNDGCTFSVEMAAAPTFETIMEDLDVC--AG 519

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
            +      V+EG P P+++W+K+ + L     Y     +    + +       S  YT  A
Sbjct: 520  ESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTA 579

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPE 1670
             N AG+ S +  L V++  SK E
Sbjct: 580  RNLAGSVSCKAELTVHEAISKEE 602



 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 113/546 (20%), Positives = 223/546 (40%), Gaps = 45/546 (8%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F  KL      +G   +F+C+V G P PQ+TW     ++  S+D ++  +     +L+
Sbjct: 83   PLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFDHLLTESEDIRILQEGGR-HSLI 141

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXXA 626
            I  V  ED G +   A+N  G A ++ EL ++ P   +S   ++M               
Sbjct: 142  ISHVTKEDEGFYIVTARNCHGEAETSAELYIQEPRPAISSQMAKMEKMPSIPEEPEIPEN 201

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
            ++     P F K      V EG + +L+C++  +P P I W   G+ I   E+  +    
Sbjct: 202  EVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLR 261

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            D+H     L I +V+    G Y  V  N+ G+A+    L +     +PP     ++S+  
Sbjct: 262  DVHS----LVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILPDPPDGTPVIESI-- 315

Query: 747  RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
              G+++ LS +      P+I     +  + A+  +S G      I    K   + +YT+ 
Sbjct: 316  -TGKTITLSWKKPKRLDPSI---DPSSLMYAIQQQSLGSIQWTIIASGLK---DTMYTI- 367

Query: 807  AENSEGIAETSAVITV-----EEPTEEN------------AEPPLFINRFQEITVKEKGT 849
            +  S+G+     V+T+      +P+                E P+ +++ + + V E  +
Sbjct: 368  SSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLLDRGPYLQEAPIIVDKPEIVYVIENQS 427

Query: 850  IKLVARVTRNPV-PSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKC 906
            + +   +T N V  ++ W R   I++    + +    D +   L +  V S+ D G+   
Sbjct: 428  VTIT--ITLNHVNAAVLWKRKGVILASKPGVYEMSMPDDDQHTLKLFKVKSD-DIGEMTF 484

Query: 907  VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNK 964
            +ASN  G  + G   ++++      + + +  +   G++    +  +        W+ + 
Sbjct: 485  MASNKHG--NDGCTFSVEMAAAPTFETIMEDLDVCAGESPRFAVVVEGKPVPDILWFKSD 542

Query: 965  KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
              ++   H   + +              D GV  C  ++   S     + T+ E I K +
Sbjct: 543  SLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTARNLAGSVSCKAELTVHEAISKEE 602

Query: 1025 DFEVKE 1030
              E +E
Sbjct: 603  PIEDEE 608



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 112/446 (25%), Positives = 183/446 (41%), Gaps = 49/446 (10%)

Query: 491 KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
           K++K+P      E P +E E+   P F++ L      +G     +C+V G P P I WF 
Sbjct: 185 KMEKMPSIPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFH 244

Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
               I+ ++D +M    D V +LVIR V     G +  V  N  G A+    L V   L 
Sbjct: 245 NGKRIESTEDRKMTQLRD-VHSLVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILP 303

Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFS-KKPKAQYVDEGSDILLECRLVAIPEPD 664
           D      V             + + G   T S KKPK   +D   D      + AI +  
Sbjct: 304 DPPDGTPV------------IESITGKTITLSWKKPKR--LDPSID--PSSLMYAIQQQS 347

Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
           +         +    I+  ++  M+   S+ K      F+  T T  A ++   A+ P+ 
Sbjct: 348 LG-------SIQWTIIASGLKDTMYTISSLSKGLRY-AFRVLTITSKAFSKPSPATDPVQ 399

Query: 725 LKIKTGE--KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKA 777
           L +  G   +E P +++  + + V + +SV ++   + +    + W +      +KP   
Sbjct: 400 L-LDRGPYLQEAPIIVDKPEIVYVIENQSVTITI-TLNHVNAAVLWKRKGVILASKPGVY 457

Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
             +  D D H++ + K K   D G  T  A N  G        +V     E A  P F  
Sbjct: 458 EMSMPDDDQHTLKLFKVKS-DDIGEMTFMASNKHG--NDGCTFSV-----EMAAAPTFET 509

Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
             +++ V    + +    V   PVP I W++++ +++ S   T  +D     LV+ N   
Sbjct: 510 IMEDLDVCAGESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACP 569

Query: 898 EIDSGDYKCVASNSAGKSSHGARVTI 923
           E DSG Y C A N AG  S  A +T+
Sbjct: 570 E-DSGVYTCTARNLAGSVSCKAELTV 594



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 51/210 (24%), Positives = 100/210 (47%), Gaps = 10/210 (4%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E ++   + G+P P ++W+ NG ++E+ ++  +T       + I+ ++ +H   Y   
Sbjct: 223  GKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSVRHAHGGVYKSV 282

Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702
             SN  G ++    L V D  P  P+G  ++  I+ +++T+ WK P   D  ++ +   YA
Sbjct: 283  ISNKVGKATCYAHLYVTDILPDPPDGTPVIESITGKTITLSWKKPKRLDPSIDPSSLMYA 342

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVI- 1760
            I++    + +W  +A   +D   Y I  L++   Y FRV+      FS+ +  ++P+ + 
Sbjct: 343  IQQQSLGSIQWTIIASGLKDT-MYTISSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLL 401

Query: 1761 ---KTALDVPSXXXXXXXXXXIDNESVYIT 1787
                   + P           I+N+SV IT
Sbjct: 402  DRGPYLQEAPIIVDKPEIVYVIENQSVTIT 431



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 1/103 (0%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S E + AP F   +       G + +F   VEG P P I WF+  +++  S  +   YDD
Sbjct: 498 SVEMAAAPTFETIMEDLDVCAGESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDD 557

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
            N  +LV+    PED+G +TC A+N AG  S   EL V   +S
Sbjct: 558 -NECSLVVLNACPEDSGVYTCTARNLAGSVSCKAELTVHEAIS 599



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 80/302 (26%), Positives = 122/302 (40%), Gaps = 44/302 (14%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVKKFQ 704
           G  +L EC +    + D+ WL  G+ I P       +   MH     C +L + +V +  
Sbjct: 1   GETVLFECHIRGPKDTDVDWLADGKLIQP-----ALLNCKMHFDGRKCRLL-LNSVHEDD 54

Query: 705 EGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
            GTYT  ++  +E   S     K++      P     L  + V +G +     +V G P 
Sbjct: 55  SGTYTCKLSTAKEEVISCG---KLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPS 111

Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
           P +TW   +  +   + +    +G  HS+ I    K +DEG Y + A N  G AETSA +
Sbjct: 112 PQVTWSHFDHLLTESEDIRILQEGGRHSLIISHVTK-EDEGFYIVTARNCHGEAETSAEL 170

Query: 821 TVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKLVA 854
            ++EP                  EE   P         P FI    ++ V E     L  
Sbjct: 171 YIQEPRPAISSQMAKMEKMPSIPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKC 230

Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
           +V   P P+I W+ N + I  +E        +   LVI +V      G YK V SN  GK
Sbjct: 231 KVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSV-RHAHGGVYKSVISNKVGK 289

Query: 915 SS 916
           ++
Sbjct: 290 AT 291



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 97/374 (25%), Positives = 147/374 (39%), Gaps = 73/374 (19%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582
           G TV FEC + G     + W     +I+P+  + +M++D      L++  V  +D+GT+T
Sbjct: 1   GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRK-CRLLLNSVHEDDSGTYT 59

Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
           C    A     S  +L V  P +D                    DILE            
Sbjct: 60  CKLSTAKEEVISCGKLRV-IPSND-------------PLFTRKLDILE------------ 93

Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
             V EG +   +C++   P P + W      +   E+I +  E   H     L I++V K
Sbjct: 94  --VIEGRNARFDCKVSGTPSPQVTWSHFDHLLTESEDIRILQEGGRHS----LIISHVTK 147

Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTG-----------EKEP-----PQV--------- 737
             EG Y V A N  GEA     L I+             EK P     P++         
Sbjct: 148 EDEGFYIVTARNCHGEAETSAELYIQEPRPAISSQMAKMEKMPSIPEEPEIPENEVERFT 207

Query: 738 ----IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD---GDTHSIT 790
               I+PL  + V +G+  +L  +V G P PTI W  N K +++   +      D HS+ 
Sbjct: 208 MPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSL- 266

Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850
           +++  +    GVY     N  G A   A + V   T+   +PP      + IT K   TI
Sbjct: 267 VIRSVRHAHGGVYKSVISNKVGKATCYAHLYV---TDILPDPPDGTPVIESITGK---TI 320

Query: 851 KLVARVTRNPVPSI 864
            L  +  +   PSI
Sbjct: 321 TLSWKKPKRLDPSI 334



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 45/192 (23%), Positives = 85/192 (44%), Gaps = 15/192 (7%)

Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-QLTI- 1156
            E  ++   PEI+  ++NQ V      T  I L   +A V W + G  +     + ++++ 
Sbjct: 409  EAPIIVDKPEIVYVIENQSV------TITITLNHVNAAVLWKRKGVILASKPGVYEMSMP 462

Query: 1157 DGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212
            D  +  LK++    DD GE     S + GN  CT   +VE  +      + E + V A  
Sbjct: 463  DDDQHTLKLFKVKSDDIGEMTFMASNKHGNDGCT--FSVEMAAAPTFETIMEDLDVCAGE 520

Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
                 V +  + + D+ W+K  S++ ++  +T + D  + +L++     +D   YTC   
Sbjct: 521  SPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTAR 580

Query: 1272 DAKSTTKLKVEV 1283
            +   +   K E+
Sbjct: 581  NLAGSVSCKAEL 592



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 9/191 (4%)

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDE-GVYTL 805
           GE+V+    + G     + W  + K ++   L  K   D     +L     +D+ G YT 
Sbjct: 1   GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTC 60

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           K   ++       VI+  +     +  PLF  +   + V E    +   +V+  P P +T
Sbjct: 61  KLSTAK-----EEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVT 115

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W   + +++ SE I    +G    L+I++V  E D G Y   A N  G++   A + I  
Sbjct: 116 WSHFDHLLTESEDIRILQEGGRHSLIISHVTKE-DEGFYIVTARNCHGEAETSAELYIQE 174

Query: 926 EKVTFVKHLQK 936
            +      + K
Sbjct: 175 PRPAISSQMAK 185



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 1/95 (1%)

Query: 510  PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
            P+F  KLR     +G  V   C   G P P ITW +    ++      M    D    L+
Sbjct: 1340 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLM 1399

Query: 570  IREVFPEDAGTFTCVAKN-AAGFASSTTELIVEAP 603
            I +   +DAG + CVA N  A  +SS T  +   P
Sbjct: 1400 IMQTTKKDAGVYECVATNPLASVSSSCTISLARLP 1434



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 6/163 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTI 1645
            GD   ++ +  G P P + W K+   LE D   N I   +   ++ I +  +  +  Y  
Sbjct: 1354 GDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLMIMQTTKKDAGVYEC 1413

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
             A+N   + S   T+ +   P++P  P I ++ +  ++ + W+P      L    Y++E+
Sbjct: 1414 VATNPLASVSSSCTISLARLPNRPGTPEIPQKYNNTALVL-WRP---SDTLAPCTYSLER 1469

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
                   W+ VA    D   Y +  L       FRV   N  G
Sbjct: 1470 RAEGEPNWLIVATGVADC-YYNVVDLPAGGVIRFRVACVNKAG 1511



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 8/116 (6%)

Query: 712  AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
            A++RE  A L      K     PP     L+  ++ +G+ V LS    G+P P ITW K+
Sbjct: 1318 AISRENSA-LRSRQYSKLASDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKD 1376

Query: 772  NKPVKA-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             KP++      +    DG  H + I++  K KD GVY   A N      +S  I++
Sbjct: 1377 KKPLEIDARMNMIACPDG-RHLLMIMQTTK-KDAGVYECVATNPLASVSSSCTISL 1430



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 36/176 (20%), Positives = 72/176 (40%), Gaps = 7/176 (3%)

Query: 1121 GNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            G    FE  +    D  V W  DG  IQ +  + ++  DG+K +L +     DD+G Y+C
Sbjct: 1    GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTC 60

Query: 1179 EVGNSK-----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233
            ++  +K     C  +  +      FT +L    ++      +        +  VTW    
Sbjct: 61   KLSTAKEEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFD 120

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289
             ++ ++E   ++ +  + +LII   T++D+  Y     +     +   E+    P+
Sbjct: 121  HLLTESEDIRILQEGGRHSLIISHVTKEDEGFYIVTARNCHGEAETSAELYIQEPR 176



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 36/176 (20%), Positives = 68/176 (38%), Gaps = 5/176 (2%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSA 1343
            +FPP      R++ +  G  VTL       P P+  W+ + K ++   +    +      
Sbjct: 1337 DFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRH 1396

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             L I +    DAG+Y+    N          +++   P+ PG P I +  +++  + W  
Sbjct: 1397 LLMIMQTTKKDAGVYECVATNPLASVSSSCTISLARLPNRPGTPEIPQKYNNTALVLWRP 1456

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             +     T   Y +E +      W+ V   +     ++ +L      RFR   VN+
Sbjct: 1457 SDTLAPCT---YSLERRAEGEPNWLIVATGVADCYYNVVDLPAGGVIRFRVACVNK 1509



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 5/95 (5%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536
            P     L++      + + L+C+  G P P +TW +D K L+        A  + R    
Sbjct: 1340 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLM 1399

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
                       Y+C+A N    V +SC + + + P
Sbjct: 1400 IMQTTKKDAGVYECVATNPLASVSSSCTISLARLP 1434



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 13/175 (7%)

Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            +  + E  I   +  DV W  DG++I+P          G   +L + +    D G Y+C 
Sbjct: 2    ETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTCK 61

Query: 1091 L---RDE--SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
            L   ++E  SC     +    P    +L   +V +G  A F+ +++      V W     
Sbjct: 62   LSTAKEEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFDH 121

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY-----SCEVGNSKCTAILTVEEP 1194
             +  S  I++  +G +  L I     +D G Y     +C  G ++ +A L ++EP
Sbjct: 122  LLTESEDIRILQEGGRHSLIISHVTKEDEGFYIVTARNCH-GEAETSAELYIQEP 175



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 6/114 (5%)

Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKP 1058
            I ++ E     V + T+P+FI+ L D +V E   A+L+ ++       +VW  +G+ I+ 
Sbjct: 192  IPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIES 251

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108
             +++   + R  +  L IR+      G Y  ++ ++    +C A + V ++ P+
Sbjct: 252  TEDRKMTQLR-DVHSLVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILPD 304


>UniRef50_A7RZM7 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 629

 Score =  103 bits (246), Expect = 7e-20
 Identities = 92/349 (26%), Positives = 146/349 (41%), Gaps = 26/349 (7%)

Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV--- 1683
            TSV+ +     +    Y   A       +  V +K   KPS P G V  + + R S    
Sbjct: 221  TSVLTVHTYDDADFGPYVCVAMTPNTNQTHVVHIKRLHKPSAP-GNVTRQRLLRPSANCS 279

Query: 1684 ---TIEWKPPLDDGGLELTKYAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYM 1738
               ++ W PPLD+GG  +T Y ++  +P    W   + A V+      C  +        
Sbjct: 280  VQTSVTWMPPLDNGGSPVTHYDVQ-FKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLE 338

Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI--TWFPSEKNGG 1796
             RV+A+N VG  E  E   + I T    P+           ++   YI  TW     +GG
Sbjct: 339  MRVMARNVVGQGEPSE---VFIVTFWGEPTPPRNLAYRLVRNDGYPYIRVTWDYPYDDGG 395

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
              +  YKVE K  G  W             R++K S    Y+ R+ A N +G S P    
Sbjct: 396  VSVNGYKVEYKATGAAWARAIQTGTFAKEVRLEKKSNLKEYEIRVIAYNGVGPSKP---- 451

Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRS-----VTLKWTEPESNGGSPITNYIIEFKTVKG 1909
             ++        PS+P N  +S +   +     + ++W  P  NGGSPIT Y++E+K    
Sbjct: 452  SEVLKAAFAEKPSRPLNVGISATALNTNHGPHIQIRWDSPLDNGGSPITEYMVEYKEEVQ 511

Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958
             +W++   V    +E  +  I    +   R+SA N++G   P++  SV+
Sbjct: 512  TNWSQGRYVEVDRNEFILTGIDRNMKYDIRVSARNSMGYGPPSKVVSVK 560



 Score =  101 bits (242), Expect = 2e-19
 Identities = 72/275 (26%), Positives = 114/275 (41%), Gaps = 13/275 (4%)

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT----YQFRIYA 1841
            +TW P   NGGSP+  Y V+ K  G+ W            I             + R+ A
Sbjct: 284  VTWMPPLDNGGSPVTHYDVQFKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLEMRVMA 343

Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
            RN +G   P +    +T     TPP      +V       + + W  P  +GG  +  Y 
Sbjct: 344  RNVVGQGEP-SEVFIVTFWGEPTPPRNLAYRLVRNDGYPYIRVTWDYPYDDGGVSVNGYK 402

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            +E+K   G +W + +  G    E  +E      E   R+ A N VG S P+E   V    
Sbjct: 403  VEYKAT-GAAWARAIQTGTFAKEVRLEKKSNLKEYEIRVIAYNGVGPSKPSE---VLKAA 458

Query: 1962 HATVPSPP-TAPLEIRMVGSNI---VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
             A  PS P    +    + +N    +   W +P  +GG+P+  Y +  ++  +T W +  
Sbjct: 459  FAEKPSRPLNVGISATALNTNHGPHIQIRWDSPLDNGGSPITEYMVEYKEEVQTNWSQGR 518

Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             V+V+  +F +  +  N  Y IR+ ARN +G   P
Sbjct: 519  YVEVDRNEFILTGIDRNMKYDIRVSARNSMGYGPP 553



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 57/212 (26%), Positives = 86/212 (40%), Gaps = 9/212 (4%)

Query: 1850 PYTSDDKITIGKTLTPPSQPRNFV------VSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
            P T+   +   K L  PS P N         S + S   ++ W  P  NGGSP+T+Y ++
Sbjct: 244  PNTNQTHVVHIKRLHKPSAPGNVTRQRLLRPSANCSVQTSVTWMPPLDNGGSPVTHYDVQ 303

Query: 1904 FKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            FK      W     V  + + H C    + ++ +  R+ A N VG   P+E   V     
Sbjct: 304  FKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLEMRVMARNVVGQGEPSEVFIVTFWGE 363

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
             T P      L +R  G   +  +W  P  DGG  + GY +  +  T   W    +    
Sbjct: 364  PTPPRNLAYRL-VRNDGYPYIRVTWDYPYDDGGVSVNGYKVEYK-ATGAAWARAIQTGTF 421

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
              +  +   S    Y IR+ A N +G S+P E
Sbjct: 422  AKEVRLEKKSNLKEYEIRVIAYNGVGPSKPSE 453



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAY 1454
            I I WD P + G S I  Y+VEY+E   T W   +   + + +  +  +  N  Y  R  
Sbjct: 484  IQIRWDSPLDNGGSPITEYMVEYKEEVQTNWSQGRYVEVDRNEFILTGIDRNMKYDIRVS 543

Query: 1455 AVNEVDISDASE 1466
            A N +     S+
Sbjct: 544  ARNSMGYGPPSK 555


>UniRef50_Q4S5Q4 Cluster: Chromosome 9 SCAF14729, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9
            SCAF14729, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 675

 Score =  102 bits (244), Expect = 1e-19
 Identities = 64/228 (28%), Positives = 100/228 (43%), Gaps = 3/228 (1%)

Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            K K G   +      G  P +V WY+ G +L ND    +      S + +   +R  + +
Sbjct: 10   KVKAGQNAIFKMQFVGQDPIKVQWYREGEELLNDTNVRVEKCTSQSRLLLSRCQRKDTGE 69

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
              I+  N  G +     L V DKPS P GP    E S   V   W+PP DDGG  ++ Y 
Sbjct: 70   IKIKLKNEHGVTEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSPVSHYV 129

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            +E+ +   N W K+  V   V TY    ++   +Y +R+ A    G SE +E++ +   T
Sbjct: 130  MERQQVGRNTWKKMG-VIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTSEMMETDEMQAGT 188

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810
             L  P            D + + + W      GGS I+ Y +E +++G
Sbjct: 189  -LAFPGPPAPPVVVSAFD-DCINLAWEAPSNRGGSRILGYILEKRKKG 234



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 51/194 (26%), Positives = 89/194 (45%), Gaps = 10/194 (5%)

Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
           M+V+ G SV ++     +P P I W K+N PV    T S+ D+ S  ++   +  D G+Y
Sbjct: 440 MVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTISNSDSSSQLLIPSSERSDSGIY 499

Query: 804 TLKAENSEGIAETSAVITVEE------PTEENAE---PPLFINRFQEITVKEKGTIKLVA 854
           ++  +N  G    S  + V E      P  ++ +   PP+F+   +   V +     +  
Sbjct: 500 SILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLKLHNVPKGYECYMSC 559

Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
            VT NP P ITWYRN+  ++       +       L+I  V  + D G+Y  +A N+ G+
Sbjct: 560 AVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPK-DMGEYTIMAENTLGR 618

Query: 915 SSHGARVTIDVEKV 928
           +     + +  E +
Sbjct: 619 AESATVLNVKGENM 632



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 46/187 (24%), Positives = 88/187 (47%), Gaps = 8/187 (4%)

Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893
            T + +I  +NE G +    +  ++T+    +PP  P     +ES++  V  +W  P+ +G
Sbjct: 67   TGEIKIKLKNEHGVT---EAISQLTVLDKPSPPLGPAE--TTESSATCVEFRWRPPKDDG 121

Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953
            GSP+++Y++E + V   +W K+  + G V  +   ++    +  +RI A    G S   E
Sbjct: 122  GSPVSHYVMERQQVGRNTWKKMGVIPG-VPTYRDTDVDHGRKYCYRIWAVTAEGTSEMME 180

Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
            +  ++    A  P PP  P+ +     + +  +W  P   GG+ +LGY +  R     +W
Sbjct: 181  TDEMQAGTLA-FPGPPAPPVVVSAF-DDCINLAWEAPSNRGGSRILGYILEKRKKGSNLW 238

Query: 2014 MEVGKVD 2020
              +   D
Sbjct: 239  STINAAD 245



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 39/179 (21%), Positives = 78/179 (43%), Gaps = 2/179 (1%)

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352
            + +  ++K G +    + +        +W    + +    + +    +  + L + + + 
Sbjct: 5    FTQAVKVKAGQNAIFKMQFVGQDPIKVQWYREGEELLNDTNVRVEKCTSQSRLLLSRCQR 64

Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNST 1411
             D G  K++L+N  G  +    +T+LDKPSPP G     E  ++ +   W  P++ G S 
Sbjct: 65   KDTGEIKIKLKNEHGVTEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSP 124

Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            + +YV+E Q++    W  +  I    T    ++     Y +R +AV     S+  ET E
Sbjct: 125  VSHYVMERQQVGRNTWKKMGVIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTSEMMETDE 183



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 68/315 (21%), Positives = 115/315 (36%), Gaps = 25/315 (7%)

Query: 1379 DKPSPPGKPNILEIDSSSIN---ICWDEPENTGN--STIIYYVVEYQEIDTTEW--ISVK 1431
            D   PPGK   L+   +S     + W +PE           Y ++ ++ D+ EW   +  
Sbjct: 321  DPKKPPGKVIGLKTSETSYTHFVLTWTKPEEKPGIQDEARGYFIDIRQADSIEWSRCNTS 380

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
             +  T  S++ LK    Y  R  A N+     A E  +Y   +        T  K    +
Sbjct: 381  PLITTSFSVKGLKPMDMYWVRVTASNDGGDGPAEEMDKYIIAMPRPVRPKFTNHKMKSFM 440

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXY 1548
              +    + +T  F   P P + W +D   + T + T  N                   Y
Sbjct: 441  VVKAGNSVRITLHFEASPLPVIMWLKDNVPV-TKRVTISNSDSSSQLLIPSSERSDSGIY 499

Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITI---SNEDIK---------QKHKV--GDEWLVTA 1594
              +  N  G+   S  V + ++ V +     + D++         + H V  G E  ++ 
Sbjct: 500  SILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLKLHNVPKGYECYMSC 559

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
             + G P P + WY+N   L  D  Y I+       + I ++      +YTI A NT G +
Sbjct: 560  AVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPKDMGEYTIMAENTLGRA 619

Query: 1655 SVEVTLKVYDKPSKP 1669
                 L V  +  +P
Sbjct: 620  ESATVLNVKGENMQP 634



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 58/215 (26%), Positives = 93/215 (43%), Gaps = 23/215 (10%)

Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           T  K      V  G+ + +     A P P I WL     +     IS +  S      S 
Sbjct: 432 TNHKMKSFMVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTISNSDSS------SQ 485

Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-------GEKE-----PPQVIEPLK 742
           L I + ++   G Y+++  N  G+ +  + +++           K+     PP  + PLK
Sbjct: 486 LLIPSSERSDSGIYSILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLK 545

Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDE 800
              V +G    +S  V GNP+P ITW +N+  +         +T  +  L   +V  KD 
Sbjct: 546 LHNVPKGYECYMSCAVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPKDM 605

Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
           G YT+ AEN+ G AE++ V+ V+    EN +P  F
Sbjct: 606 GEYTIMAENTLGRAESATVLNVK---GENMQPIQF 637



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 48/163 (29%), Positives = 66/163 (40%), Gaps = 4/163 (2%)

Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-W 1813
            +E I   T LD PS               V   W P + +GGSP+  Y +E +Q G+  W
Sbjct: 81   TEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSPVSHYVMERQQVGRNTW 140

Query: 1814 KXXXXX-XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872
            K           R   +     Y +RI+A    GTS      D++  G TL  P  P   
Sbjct: 141  KKMGVIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTS-EMMETDEMQAG-TLAFPGPPAPP 198

Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
            VV  +    + L W  P + GGS I  YI+E +      W+ I
Sbjct: 199  VVVSAFDDCINLAWEAPSNRGGSRILGYILEKRKKGSNLWSTI 241



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 3/93 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATL 568
           P+FV  L+  + P G      C V G P+P+ITW+R    I  + D   Y  +   V +L
Sbjct: 538 PVFVVPLKLHNVPKGYECYMSCAVTGNPKPRITWYRNH--ISLNTDTNYYISNTCGVCSL 595

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           +I +V P+D G +T +A+N  G A S T L V+
Sbjct: 596 LILQVGPKDMGEYTIMAENTLGRAESATVLNVK 628



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 6/131 (4%)

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            +   + KD    +I  +N  GV+    SQ   L+K    PSPP  P E     +  V   
Sbjct: 59   LSRCQRKDTGEIKIKLKNEHGVT-EAISQLTVLDK----PSPPLGPAETTESSATCVEFR 113

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ DGG+P+  Y +  + V +  W ++G +      +   D+     Y  RI+A   
Sbjct: 114  WRPPKDDGGSPVSHYVMERQQVGRNTWKKMGVIP-GVPTYRDTDVDHGRKYCYRIWAVTA 172

Query: 2047 IGLSEPLESDE 2057
             G SE +E+DE
Sbjct: 173  EGTSEMMETDE 183



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 51/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (9%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G++V+     E  P P I W +    +          + D+ + L+I      D+G ++ 
Sbjct: 445 GNSVRITLHFEASPLPVIMWLKDNVPVTKRVTIS---NSDSSSQLLIPSSERSDSGIYSI 501

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           + KN AG  + + E+ V        +E  V                   PP F    K  
Sbjct: 502 LLKNLAGQETFSLEVRV--------TERFVTSTPARKDRDLQC------PPVFVVPLKLH 547

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            V +G +  + C +   P+P I W      +  D N  +   S+    CS+L I  V   
Sbjct: 548 NVPKGYECYMSCAVTGNPKPRITWYRNHISLNTDTNYYI---SNTCGVCSLL-ILQVGPK 603

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
             G YT++A N  G A    VL +K    +P Q
Sbjct: 604 DMGEYTIMAENTLGRAESATVLNVKGENMQPIQ 636



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 18/59 (30%), Positives = 30/59 (50%)

Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
            EM    L  P PP  P ++      IN+ W+ P N G S I+ Y++E ++  +  W ++
Sbjct: 183  EMQAGTLAFPGPPAPPVVVSAFDDCINLAWEAPSNRGGSRILGYILEKRKKGSNLWSTI 241



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 2/82 (2%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            +K G+ V + + ++A P P   W+ ++  + K + T  + DS S+ L I   E +D+GIY
Sbjct: 442  VKAGNSVRITLHFEASPLPVIMWLKDNVPVTK-RVTISNSDS-SSQLLIPSSERSDSGIY 499

Query: 1359 KLRLENNCGHADVEMNVTILDK 1380
             + L+N  G     + V + ++
Sbjct: 500  SILLKNLAGQETFSLEVRVTER 521



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 26/115 (22%), Positives = 44/115 (38%), Gaps = 2/115 (1%)

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894
            Y+FR+ A N  G     +  + +       PP +      SE++     L WT+PE   G
Sbjct: 295  YEFRVTAVNLSGPGECSSPSEFVFARDPKKPPGKVIGLKTSETSYTHFVLTWTKPEEKPG 354

Query: 1895 --SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
                   Y I+ +      W++  T         ++ +K  D    R++A N  G
Sbjct: 355  IQDEARGYFIDIRQADSIEWSRCNTSPLITTSFSVKGLKPMDMYWVRVTASNDGG 409



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 5/99 (5%)

Query: 833 PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
           P F N   +  + VK   ++++      +P+P I W ++N  ++   TI+ N D  + +L
Sbjct: 429 PKFTNHKMKSFMVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTIS-NSDSSS-QL 486

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
           +I + +   DSG Y  +  N AG+ +    V +    VT
Sbjct: 487 LIPSSERS-DSGIYSILLKNLAGQETFSLEVRVTERFVT 524


>UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell
            adhesion molecule; n=1; Monodelphis domestica|Rep:
            PREDICTED: similar to L1 cell adhesion molecule -
            Monodelphis domestica
          Length = 1344

 Score =  101 bits (242), Expect = 2e-19
 Identities = 170/781 (21%), Positives = 303/781 (38%), Gaps = 57/781 (7%)

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
            RG  + L    + FP P  +W   S  ++  + T  + +    +L + +VE  D G Y+ 
Sbjct: 344  RGQPLVLECIAEGFPTPTIKWSYPSNQMQAGRVTYQNFNK---TLRLVRVEEEDDGEYRC 400

Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTGNSTIIYYVV 1417
              EN  G A     VT+   P    +P  L +   +++ +N C  +       T     V
Sbjct: 401  WAENTLGSAQHVYYVTVEAAPYWLQEPESLVLAPGETARLN-CQVQGRPRPMVTWRINGV 459

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK-E 1476
              + +   + + V+        + N++ N +   +  A N+  +  A+    Y  V++  
Sbjct: 460  SLENLTRDDKLRVQG---GALILSNVQPNDTMVTQCEARNKHGLLLANA---YISVVQLP 513

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-RD-GKKLKTAKATYENRXX 1534
            TKI +P   K  + +         L C   GVP P + W  RD    L+  +        
Sbjct: 514  TKILTPD-NKTYREVQ---GSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGT 569

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED--IKQKHKVGDEWLV 1592
                         Y C A ND   V     + +++   I    ED  +K+   V    LV
Sbjct: 570  LAIRDLQTNDTGSYFCQADNDQNRVSIKAHLQVKEATQIKKGPEDRTVKKGSNVNFPCLV 629

Query: 1593 TAVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +   +     ++ WY N   +++  KE     KE+   + I  L  +    Y+  A    
Sbjct: 630  S--FDPSLNIQIDWYWNDQNIKDFYKEDKYLIKEEE--LTIISLDYADQGNYSCVAKTAL 685

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP--D 1709
             +   + T+ V   P  P G + + +     V + W P  ++    + KY IE  +   +
Sbjct: 686  DSVEKKATVLVVGSPG-PVGQLELYKQKDFHVQLSWSPA-EEHNSPIEKYNIEFEDRTME 743

Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768
               W  +A V  + ET    KL+    Y FRVIA N  G SE + +SEP +  T   VP 
Sbjct: 744  PGTWYPLATVPGN-ETSTRLKLSPFVHYNFRVIANNKFGASEPSPDSEPFI--TPKSVPE 800

Query: 1769 XXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI 1826
                       +  ++ ITW P +  +   P + Y+V+ +Q+ + +W+           +
Sbjct: 801  KNPTNVKGEGNETNNMVITWKPLKWIDWNGPELKYRVQWRQKNESEWREVMVRASKYV-V 859

Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE-STSRSVTLK 1885
                    Y+ ++ A NE+G       D  I IG +     Q    V  E   + +V +K
Sbjct: 860  SNTPTFVPYEIKVQAINEVGKG----PDPHIVIGYSGEDVPQAIPIVAIELLNATTVRIK 915

Query: 1886 WTEPESN------GGSPITNYIIEFKTVKGKSWT--KIVTVGGSVHEHCIENIKEKDEII 1937
            W   + N       G  +T + +  +  + K  T   I+    S  E  + +++     I
Sbjct: 916  WEPVDLNEVRGHLRGYRVTYWWVNSRWSRSKRHTPKTIIDKPASAMEAVLPDLRPYS--I 973

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
            + +  +     SL   S++++ E    VP  P + L +R +    +  SW  P  +    
Sbjct: 974  YSVHVQVFNSRSLGPPSETIKFETEEGVPDRPQS-LNLRRLSDTALQLSW-RPPLNPNGE 1031

Query: 1998 LLGYNIAIRDVT-KTMWMEVGK-VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            L GY +  R    +    E+ + +   TL FN+ DL     Y  ++ A  ++G  E +  
Sbjct: 1032 LKGYQLIYRPFNQEPEENEMTEFLPPTTLMFNLSDLKPQTLYRFQLRATTKVGPGEMITQ 1091

Query: 2056 D 2056
            +
Sbjct: 1092 E 1092



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 93/397 (23%), Positives = 161/397 (40%), Gaps = 39/397 (9%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  ++LEC     P P I W +   ++       V  ++    +   L++  V++  +G 
Sbjct: 345  GQPLVLECIAEGFPTPTIKWSYPSNQMQAGR---VTYQN----FNKTLRLVRVEEEDDGE 397

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y   A N  G A     + +   E  P  + EP +S+++  GE+  L+ QV G PRP +T
Sbjct: 398  YRCWAENTLGSAQHVYYVTV---EAAPYWLQEP-ESLVLAPGETARLNCQVQGRPRPMVT 453

Query: 768  WCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
            W  N   ++ L T+ D         IL   +  D  V   +A N  G+   +A I+V + 
Sbjct: 454  WRINGVSLENL-TRDDKLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQL 512

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEIISPSETITQNFD 884
              +   P      ++E+   +  T  L+      P+PSI W  R+   +   E      +
Sbjct: 513  PTKILTPD--NKTYREV---QGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYAN 567

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944
            G    L I ++ +  D+G Y C A N   + S   +  + V++ T +K   +    ++G 
Sbjct: 568  G---TLAIRDLQTN-DTGSYFCQADNDQNRVS--IKAHLQVKEATQIKKGPEDRTVKKGS 621

Query: 945  TVILECQTSH----TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
             V   C  S      +   WY N + I    ++E     +            D G   C+
Sbjct: 622  NVNFPCLVSFDPSLNIQIDWYWNDQNIKDF-YKEDKYLIKEEELTIISLDYADQGNYSCV 680

Query: 1001 VKD-----QETSTMLVVKETIPE---FIRKLQDFEVK 1029
             K      ++ +T+LVV    P     + K +DF V+
Sbjct: 681  AKTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQ 717



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 76/331 (22%), Positives = 141/331 (42%), Gaps = 21/331 (6%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWL-FKGEEIVPDENISVAIE 685
           + EG P    +K +   V+EG  ++L C   A   +P I W+  +   I  DE +++   
Sbjct: 219 VAEGAPKWPKEKVQPFEVEEGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQN 278

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEP-- 740
            +++ + +VL  TN        +      R      PI L++K         P+++ P  
Sbjct: 279 GNLY-FANVL--TNDSHSDYICHAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEG 335

Query: 741 LKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799
           L S +V  +G+ ++L     G P PTI W   +  ++A          ++ +++ ++ +D
Sbjct: 336 LTSRLVALRGQPLVLECIAEGFPTPTIKWSYPSNQMQAGRVTYQNFNKTLRLVRVEE-ED 394

Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
           +G Y   AEN+ G A+    +TVE         P ++   + + +    T +L  +V   
Sbjct: 395 DGEYRCWAENTLGSAQHVYYVTVE-------AAPYWLQEPESLVLAPGETARLNCQVQGR 447

Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
           P P +TW R N +   + T       +   L+++NV    D+   +C A N  G     A
Sbjct: 448 PRPMVTW-RINGVSLENLTRDDKLRVQGGALILSNVQPN-DTMVTQCEARNKHGLLLANA 505

Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
            +++       +    K+Y   +G T  L C
Sbjct: 506 YISVVQLPTKILTPDNKTYREVQGSTAYLLC 536



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 79/333 (23%), Positives = 134/333 (40%), Gaps = 27/333 (8%)

Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           PP  +++ P+   V    DI+L+C     PE    W  +     P++ +      +   +
Sbjct: 124 PPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGSF 183

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
                 +N  +  +GTY   A NR G A S  I L  +   K P + ++P +   V +G+
Sbjct: 184 IITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAEGAPKWPKEKVQPFE---VEEGQ 240

Query: 751 SVILSAQVVGNP-RPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
           SV+L      +  +P I W  +        + +    +G+ +   +L      D   Y  
Sbjct: 241 SVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQNGNLYFANVLTNDSHSD---YIC 297

Query: 806 KAE--NSEGIAETSAVITVEEPTEE--NAEPPLFI-NRFQEITVKEKGTIKLVARVTRN- 859
            A    +  I +   +    +PT       P L +        V  +G   ++  +    
Sbjct: 298 HAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECIAEGF 357

Query: 860 PVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
           P P+I W Y +N++ +   T  QNF   N  L +  V+ E D G+Y+C A N+ G + H 
Sbjct: 358 PTPTIKWSYPSNQMQAGRVTY-QNF---NKTLRLVRVEEE-DDGEYRCWAENTLGSAQHV 412

Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
             VT  VE   +     +S     G+T  L CQ
Sbjct: 413 YYVT--VEAAPYWLQEPESLVLAPGETARLNCQ 443



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 97/433 (22%), Positives = 176/433 (40%), Gaps = 36/433 (8%)

Query: 1083 DEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVR 1138
            D+GEY C   +   +A+      VE  P  +   ++  +  G  A    ++  +   +V 
Sbjct: 394  DDGEYRCWAENTLGSAQHVYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVT 453

Query: 1139 WFKDGSEIQ-FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            W  +G  ++  +   +L + G    L + +   +D     CE  N K   +L     S+ 
Sbjct: 454  WRINGVSLENLTRDDKLRVQGGA--LILSNVQPNDTMVTQCEARN-KHGLLLANAYISV- 509

Query: 1198 FTLRLPEFILVPAN--------TDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLIS 1246
              ++LP  IL P N        + AYL      +P  ++      + +V++D E+F   +
Sbjct: 510  --VQLPTKILTPDNKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQD-ERFVPYA 566

Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDV 1305
            +    TL IR    +D   Y C   + ++   +K  + V+   +I     +  +K+GS+V
Sbjct: 567  N---GTLAIRDLQTNDTGSYFCQADNDQNRVSIKAHLQVKEATQIKKGPEDRTVKKGSNV 623

Query: 1306 TL--LVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
                LV +        +W  N + IK   K  K  I  K   LTI  ++  D G Y    
Sbjct: 624  NFPCLVSFDPSLNIQIDWYWNDQNIKDFYKEDKYLI--KEEELTIISLDYADQGNYSCVA 681

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE- 1421
            +      + +  V ++  P P G+  + +     + + W  P    NS I  Y +E+++ 
Sbjct: 682  KTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQLSW-SPAEEHNSPIEKYNIEFEDR 740

Query: 1422 -IDTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
             ++   W  +  +   +TS +  L     Y FR  A N+   S+ S  +E +   K    
Sbjct: 741  TMEPGTWYPLATVPGNETSTRLKLSPFVHYNFRVIANNKFGASEPSPDSEPFITPKSVPE 800

Query: 1480 QSPTVEKPLKNIT 1492
            ++PT  K   N T
Sbjct: 801  KNPTNVKGEGNET 813



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 61/293 (20%), Positives = 117/293 (39%), Gaps = 20/293 (6%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P + ++P++  +  G    L C++   P P + W   G  +   EN++   +  + +   
Sbjct: 421 PYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSL---ENLT--RDDKLRVQGG 475

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESV 752
            L ++NV+          A N+ G       + +    + P +++ P  K+    QG + 
Sbjct: 476 ALILSNVQPNDTMVTQCEARNKHGLLLANAYISV---VQLPTKILTPDNKTYREVQGSTA 532

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            L     G P P+I W   ++       +     +    ++  +  D G Y  +A+N + 
Sbjct: 533 YLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDTGSYFCQADNDQN 592

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870
                A + V+E T+    P       ++ TVK+   +     V+ +P  +  I WY N+
Sbjct: 593 RVSIKAHLQVKEATQIKKGP-------EDRTVKKGSNVNFPCLVSFDPSLNIQIDWYWND 645

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           + I       +    E  EL I ++D   D G+Y CVA  +       A V +
Sbjct: 646 QNIKDFYKEDKYLIKEE-ELTIISLD-YADQGNYSCVAKTALDSVEKKATVLV 696



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 124/598 (20%), Positives = 218/598 (36%), Gaps = 71/598 (11%)

Query: 733  EPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHS 788
            +PP + E   + ++V   + ++L  +  G P     W K N    P K L   +  ++ S
Sbjct: 123  QPPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGS 182

Query: 789  ITILKPKK---VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845
              I         + +G Y   A N  G A +  +  V E       P     + Q   V+
Sbjct: 183  FIITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAE-----GAPKWPKEKVQPFEVE 237

Query: 846  EKGTIKLVARVTRNPVPSITWYRNNEI--ISPSETITQNFDGENIELVITNVDSEIDSGD 903
            E  ++ L      + V    ++ N+ I  I+  E +T    G+N  L   NV +     D
Sbjct: 238  EGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTM---GQNGNLYFANVLTNDSHSD 294

Query: 904  YKCVASNSAGKSSHGARVTIDVE------------KVTFVKHLQKSYETEEGKTVILEC- 950
            Y C A +  G  +   +  ID+             ++   + L        G+ ++LEC 
Sbjct: 295  YICHA-HFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECI 353

Query: 951  -QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009
             +   T + KW +   +   M    +  +              D G  +C  ++   S  
Sbjct: 354  AEGFPTPTIKWSYPSNQ---MQAGRVTYQNFNKTLRLVRVEEEDDGEYRCWAENTLGSAQ 410

Query: 1010 ---LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065
                V  E  P ++++ +   +   + A L  ++      +V W  +G  +  +    D 
Sbjct: 411  HVYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRING--VSLENLTRDD 468

Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKG 1121
            + R     L + N   +D     C  R++       A ++VV+LP +I+T          
Sbjct: 469  KLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQLPTKILT--------PD 520

Query: 1122 NKATFEIELTKGDALVRWF-KDGSEIQFSNHIQLTI--DGK-----KQKLKIYDCDLDDA 1173
            NK   E++ +    L   F      IQ+ N  Q T+  D +        L I D   +D 
Sbjct: 521  NKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDT 580

Query: 1174 GEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLD 1226
            G Y C+  N +      A L V+E +     + PE   V   ++      +   P   + 
Sbjct: 581  GSYFCQADNDQNRVSIKAHLQVKEAT--QIKKGPEDRTVKKGSNVNFPCLVSFDPSLNIQ 638

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284
            + WY     I+D  K      +K+  L I      DQ  Y+CV   A  + + K  V+
Sbjct: 639  IDWYWNDQNIKDFYKEDKYL-IKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVL 695



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 8/136 (5%)

Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV---PSP-PTAPLEIRMVGSNIVMT 1985
            IKE++  I  +   +    S   ++    +EK ATV    SP P   LE+       V  
Sbjct: 659  IKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQL 718

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
            SW +P  +  +P+  YNI   D T     W  +  V  N     ++ LS    Y  R+ A
Sbjct: 719  SW-SPAEEHNSPIEKYNIEFEDRTMEPGTWYPLATVPGNETSTRLK-LSPFVHYNFRVIA 776

Query: 2044 RNEIGLSEPLESDEPF 2059
             N+ G SEP    EPF
Sbjct: 777  NNKFGASEPSPDSEPF 792



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVAT 567
           AP ++++        G T +  CQV+G PRP +TW     ++   ++D ++         
Sbjct: 420 APYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSLENLTRDDKLRVQG---GA 476

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
           L++  V P D     C A+N  G   +   + +V+ P
Sbjct: 477 LILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQLP 513



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC  EG+P P I W   +      Q  ++ Y + N  TL +  V  ED G + C
Sbjct: 345 GQPLVLECIAEGFPTPTIKWSYPS---NQMQAGRVTYQNFN-KTLRLVRVEEEDDGEYRC 400

Query: 584 VAKNAAGFASSTTELIVEA 602
            A+N  G A     + VEA
Sbjct: 401 WAENTLGSAQHVYYVTVEA 419



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 5/79 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           GST    C   G P P I W  R  A +   + F  Y +     TL IR++   D G++ 
Sbjct: 529 GSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYAN----GTLAIRDLQTNDTGSYF 584

Query: 583 CVAKNAAGFASSTTELIVE 601
           C A N     S    L V+
Sbjct: 585 CQADNDQNRVSIKAHLQVK 603


>UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
           SCAF15002, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1098

 Score =  101 bits (242), Expect = 2e-19
 Identities = 95/378 (25%), Positives = 156/378 (41%), Gaps = 26/378 (6%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
           +I  A  SD G  + V            A+++    P   ++P  Q V E   +  +C +
Sbjct: 175 MISHARKSDAGMYVCVGKNMVGERDSDPAELVVYERPVLVRRPVNQVVMEEDTVDFQCEV 234

Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
              P P + W  +  E+ P     +      H   ++L++ +VK+  EG YT  + N  G
Sbjct: 235 HGDPAPTVRWRREEGEL-PRGRFEI------HNG-NILRLFHVKEEDEGMYTCTSENSVG 286

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777
           +     +L++      PPQ+    +  I  QG SV       GNP P I W K    +  
Sbjct: 287 KTEASAMLQVHV----PPQIATKPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLL 342

Query: 778 LPTK--SDGDTHSITI-----LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
            P +  S    +S+++     +     +D G Y  +A +  G   +  ++ V E    N 
Sbjct: 343 FPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKVLLDV-EGGPSNR 401

Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            PP+        T     T++L  RV   P   I+W +N E +  +E        EN  L
Sbjct: 402 IPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLM--ENGTL 459

Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVIL 948
            IT++  E DSG Y C+AS++ G+SS    +T+    V     + +  +      K V+ 
Sbjct: 460 QITDI-KETDSGTYTCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPVMT 518

Query: 949 ECQTSHTVSTKWYHNKKE 966
           E  T +TV+  W  N  E
Sbjct: 519 EV-TKNTVTLTWQSNPHE 535



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 129/537 (24%), Positives = 211/537 (39%), Gaps = 58/537 (10%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL---PTKS----- 782
            E  PP++ E    +IV +GE   L+ +  G P P I W K+ + V+     P        
Sbjct: 13   EDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLP 72

Query: 783  DGDTHSITILKPKKVK-DEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINRFQ 840
             G    + I+  ++ K DEGVYT  A N  G A + +A + V    ++  + P  +    
Sbjct: 73   SGSLFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDV---- 128

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             +   E   ++ V     +P P + W RNN  I   +       G+   L+I++     D
Sbjct: 129  VVAAGEPAVLECVPP-RGHPEPIVFWKRNNVRIGSKDDRIAMRGGK---LMISHARKS-D 183

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVST 958
            +G Y CV  N  G+        +  E+   V+        EE  TV  +C+       + 
Sbjct: 184  AGMYVCVGKNMVGERDSDPAELVVYERPVLVRRPVNQVVMEED-TVDFQCEVHGDPAPTV 242

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKE 1014
            +W   + E+     R  I  G             D G+  C  ++     E S ML V  
Sbjct: 243  RWRREEGELPR--GRFEIHNGNILRLFHVKEE--DEGMYTCTSENSVGKTEASAMLQV-H 297

Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGE--IIKP-----KKNKYDFE 1066
              P+   K +D    + + V        +    + W+++G   ++ P     +  +Y   
Sbjct: 298  VPPQIATKPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVS 357

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSC--ILRDESCTAEVTV-VE------LPPEIITRLQNQK 1117
              G    L I +    D G Y C  I    S  ++V + VE      +PP I     NQ 
Sbjct: 358  MSGD---LTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQT 414

Query: 1118 VNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
               G        +  G ++ + W K+G E+   N  +LT+  +   L+I D    D+G Y
Sbjct: 415  ATLGATVQLHCRVIGGPSIHISWEKNGEELH-GNEARLTLM-ENGTLQITDIKETDSGTY 472

Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
            +C      G S  +  LTV E  +  T R+ EFI +P      +  E+   T+ +TW
Sbjct: 473  TCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPVMTEVTKNTVTLTW 529



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 117/481 (24%), Positives = 193/481 (40%), Gaps = 56/481 (11%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-----DGE 886
            PP       ++ V +     L  +    P P I WY++ E +       ++       G 
Sbjct: 16   PPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLPSGS 75

Query: 887  NIEL-VITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGK 944
               L ++    S+ D G Y CVA N  G++ S  A + + + +  F +          G+
Sbjct: 76   LFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDF-RQAPSDVVVAAGE 134

Query: 945  TVILEC--QTSHTVSTK-WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
              +LEC     H      W  N   I   D R  ++ G+            D G+  C+ 
Sbjct: 135  PAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMISHARKS---DAGMYVCVG 191

Query: 1002 KDQ-----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD-GE 1054
            K+           LVV E  P  +R+  +  V E+D    + E++ + A  V W R+ GE
Sbjct: 192  KNMVGERDSDPAELVVYER-PVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGE 250

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIIT 1111
            +    + +++    G+I +L+  +    DEG Y+C   +     E +    V +PP+I T
Sbjct: 251  L---PRGRFEIHN-GNILRLF--HVKEEDEGMYTCTSENSVGKTEASAMLQVHVPPQIAT 304

Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK-----KQKLKI 1165
            + ++Q   +G   TFE   T      + W K+GS++        +  G+        L I
Sbjct: 305  KPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTI 364

Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL--TV 1218
             D   +D+G Y C+     G+     +L VE    N   R+P  I   PAN  A L  TV
Sbjct: 365  TDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSN---RIPPIIRQGPANQTATLGATV 421

Query: 1219 E-----IPDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
            +     I   ++ ++W K    +   E + TL   ++  TL I    E D   YTC+   
Sbjct: 422  QLHCRVIGGPSIHISWEKNGEELHGNEARLTL---MENGTLQITDIKETDSGTYTCIASS 478

Query: 1273 A 1273
            A
Sbjct: 479  A 479



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 108/488 (22%), Positives = 178/488 (36%), Gaps = 52/488 (10%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD----ENISVAIE 685
            E  PP  ++ P    V +G    L C+    P P I W   GE +  D     +  + + 
Sbjct: 13   EDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLP 72

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-----ASLPIVLKIKTGEKEPPQVIEP 740
            S    +  ++     K   EG YT VA N  GE     ASL + + ++   ++ P     
Sbjct: 73   SGSLFFLRIVHGRRSKP-DEGVYTCVARNYLGEAVSRNASLDVAI-LRDDFRQAP----- 125

Query: 741  LKSMIVRQGESVILS-AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799
               ++V  GE  +L      G+P P + W +NN  + +   +       + I   +K  D
Sbjct: 126  -SDVVVAAGEPAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMISHARK-SD 183

Query: 800  EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
             G+Y    +N  G  ++     V        E P+ + R     V E+ T+     V  +
Sbjct: 184  AGMYVCVGKNMVGERDSDPAELVV------YERPVLVRRPVNQVVMEEDTVDFQCEVHGD 237

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P++ W R        E     F+  N  ++      E D G Y C + NS GK+   A
Sbjct: 238  PAPTVRWRREE-----GELPRGRFEIHNGNILRLFHVKEEDEGMYTCTSENSVGKTEASA 292

Query: 920  RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ 977
             + + V      K   +     +G++V  EC T+     +  W     ++     +   Q
Sbjct: 293  MLQVHVPPQIATK--PRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQ 350

Query: 978  EGRXXXXXXXXXXXXDV-----GVIKCIVKDQETSTMLVV--------KETIPEFIRKLQ 1024
             GR            DV     G   C       S M  V           IP  IR+  
Sbjct: 351  SGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGP 410

Query: 1025 DFEVKEKDVAI-LEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
              +       + L    I   +  + WE++GE +   + +    + G ++   I+ T   
Sbjct: 411  ANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLMENGTLQITDIKET--- 467

Query: 1083 DEGEYSCI 1090
            D G Y+CI
Sbjct: 468  DSGTYTCI 475



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 86/365 (23%), Positives = 148/365 (40%), Gaps = 48/365 (13%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P+ V +   +   +  TV F+C+V G P P + W R+   + P   F+++  + N+  L 
Sbjct: 211 PVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGEL-PRGRFEIH--NGNILRLF 267

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
              V  ED G +TC ++N+ G   ++  L V  P         +              + 
Sbjct: 268 --HVKEEDEGMYTCTSENSVGKTEASAMLQVHVP-------PQIATKPRDQIATQGRSVT 318

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
                T +  P   +  EGS +L               LF G+        SV++  D  
Sbjct: 319 FECGTTGNPPPAIFWQKEGSQML---------------LFPGQPPSQSGRYSVSMSGD-- 361

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQVIEPLKSMIVR 747
                L IT+V     G Y   A++  G     ++L ++ G   + PP + +   +    
Sbjct: 362 -----LTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTAT 416

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804
            G +V L  +V+G P   I+W KN + +   +A  T  +  T  IT +K     D G YT
Sbjct: 417 LGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLMENGTLQITDIKE---TDSGTYT 473

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A ++ G +  S  +TV E    +      I+ F ++    +  +  +  VT+N V ++
Sbjct: 474 CIASSATGESSWSGTLTVREYGVYSTSR---ISEFIQLPGPPQKPV--MTEVTKNTV-TL 527

Query: 865 TWYRN 869
           TW  N
Sbjct: 528 TWQSN 532



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 74/302 (24%), Positives = 121/302 (40%), Gaps = 34/302 (11%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---------KTAKATYENRXXXX 1536
            KP   I T+    +   C   G P P + W ++G ++         ++ + +        
Sbjct: 305  KPRDQIATQ-GRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLT 363

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS----NEDIKQKHKVGDEWLV 1592
                       Y C A +  G V +  ++ ++  P   I          Q   +G    +
Sbjct: 364  ITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQL 423

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
               + G P   + W KNG +L  + E  +T  E    ++I ++K + S  YT  AS+  G
Sbjct: 424  HCRVIGGPSIHISWEKNGEELHGN-EARLTLMEN-GTLQITDIKETDSGTYTCIASSATG 481

Query: 1653 TSSVEVTLKVYDK--------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
             SS   TL V +               P  P+ PV M E+++ +VT+ W+    +GG  +
Sbjct: 482  ESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPV-MTEVTKNTVTLTWQSNPHEGGAAV 540

Query: 1699 TKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756
            T Y IE       + W  VAD  +  E + +  L  N  Y+F V A N  G S+    SE
Sbjct: 541  TSYIIEAFSQSVGSTWQTVADHVKQ-ERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599

Query: 1757 PI 1758
            P+
Sbjct: 600  PV 601



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 109/522 (20%), Positives = 201/522 (38%), Gaps = 57/522 (10%)

Query: 993  DVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSETAD 1046
            D GV  C+ ++        +  L V     +F +   D  V   + A+LE V        
Sbjct: 90   DEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDVVVAAGEPAVLECVPPRGHPEP 149

Query: 1047 VV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD-----ESCTAEV 1100
            +V W+R+   I  K ++     RG   KL I +    D G Y C+ ++     +S  AE+
Sbjct: 150  IVFWKRNNVRIGSKDDR--IAMRGG--KLMISHARKSDAGMYVCVGKNMVGERDSDPAEL 205

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGK 1159
             V E P  ++ R  NQ V + +   F+ E+    A  VRW ++  E+      ++     
Sbjct: 206  VVYERPV-LVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGELP-RGRFEIH---N 260

Query: 1160 KQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
               L+++    +D G Y+C     VG ++ +A+L V  P      +  + I     +  +
Sbjct: 261  GNILRLFHVKEEDEGMYTCTSENSVGKTEASAMLQVHVPP-QIATKPRDQIATQGRSVTF 319

Query: 1216 LTVEIPDETLDVTWYKKKSVI-----EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
                  +    + W K+ S +     +   +    S      L I     +D   Y C  
Sbjct: 320  ECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQA 379

Query: 1271 LDAKSTTKLKVEV-VE------FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
            +    +   KV + VE       PP I           G+ V L       P  +  W  
Sbjct: 380  ISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEK 439

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI------ 1377
            N + +   +     +++   +L I  ++ TD+G Y     +  G +     +T+      
Sbjct: 440  NGEELHGNEARLTLMEN--GTLQITDIKETDSGTYTCIASSATGESSWSGTLTVREYGVY 497

Query: 1378 --------LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEW 1427
                    +  P PP KP + E+  +++ + W    + G + +  Y++E   Q + +T  
Sbjct: 498  STSRISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQ 557

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
                ++ + + ++  L  N+ Y F   AVN   +SD S  +E
Sbjct: 558  TVADHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 82/391 (20%), Positives = 139/391 (35%), Gaps = 34/391 (8%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543
            V +P+  +  E  + ++  C   G P P V W R+  +L   +    N            
Sbjct: 214  VRRPVNQVVME-EDTVDFQCEVHGDPAPTVRWRREEGELPRGRFEIHNGNILRLFHVKEE 272

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
                Y C + N  G+ E S ++ +   P I     D  Q    G          G PPP 
Sbjct: 273  DEGMYTCTSENSVGKTEASAMLQVHVPPQIATKPRD--QIATQGRSVTFECGTTGNPPPA 330

Query: 1604 VIWYKNGNKL-----ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            + W K G+++     +   +    +   +  + I ++    S  Y  +A + AG+   +V
Sbjct: 331  IFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKV 390

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD---DGG----LELTKYAIEKHEPD-- 1709
             L V   PS    P+I +  + ++ T+     L     GG    +   K   E H  +  
Sbjct: 391  LLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEAR 450

Query: 1710 ----NNRWIKVADV-DRDVETY-CIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKT 1762
                 N  +++ D+ + D  TY CI             +     G +S +  SE I +  
Sbjct: 451  LTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPG 510

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWKXXXXXX 1820
                P           +   +V +TW  +   GG+ +  Y +E   +  G  W+      
Sbjct: 511  PPQKP-------VMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQTVADHV 563

Query: 1821 XXXAR-IQKLSINTTYQFRIYARNEIGTSLP 1850
                  +  L  NT Y F + A N  G S P
Sbjct: 564  KQERHTVVGLFPNTVYLFIVRAVNSYGLSDP 594



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 3/104 (2%)

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVT 1917
            I + +  P  P+  V++E T  +VTL W      GG+ +T+YIIE F    G +W + V 
Sbjct: 502  ISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTW-QTVA 560

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLE 1960
                   H +  +      +F + A N+ G+S P+  S+ VR +
Sbjct: 561  DHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISEPVRTQ 604



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 3/108 (2%)

Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEV 2016
            R+ +   +P PP  P+ +  V  N V  +W +   +GGA +  Y I A      + W  V
Sbjct: 501  RISEFIQLPGPPQKPV-MTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQTV 559

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064
                V   +  +  L  N  Y+  + A N  GLS+P    EP +   G
Sbjct: 560  AD-HVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISEPVRTQDG 606


>UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome
            shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11
            SCAF14528, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1154

 Score =  101 bits (241), Expect = 3e-19
 Identities = 126/514 (24%), Positives = 206/514 (40%), Gaps = 56/514 (10%)

Query: 629  LEGIPPTFSKKPKAQY----VDEGSDILLECRLV-AIPEPDIAWL-FKGEEIVPDENISV 682
            +E I P   K PK       V+EG   +L+C     IP   I W+    + I  DE +S 
Sbjct: 95   IEFIVPNVPKFPKETIDPVVVEEGQPFVLKCNPPDGIPPLQIYWMTISLQHIEQDERVST 154

Query: 683  AIESDMHM-----------YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731
            ++  D++            YC       ++   + T   V V  + +AS  +   I   +
Sbjct: 155  SLNGDLYFSHAVDKDSRRDYCCFAAFPRIRTIVQKTAMSVIVKTKKDASPEVANAIL--Q 212

Query: 732  KEPPQVIEPLKSMIVR--QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789
            + P  +  P      R  +GE + L     G P P + W K  +    LPTK+  ++H  
Sbjct: 213  RRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKMGQ---RLPTKATIESHGK 269

Query: 790  TILKPK-KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEK 847
             +  P  + +D G Y  KA+N+ G A     +TVE P E  +EP   ++    ++ +K  
Sbjct: 270  LLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIGSDVLIK-- 327

Query: 848  GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907
                    V+  P P++TW  N   +  S    +   G+ I L  T      DS  Y+C 
Sbjct: 328  ------CSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPS---DSAVYQCE 378

Query: 908  ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967
            ASN  G     A + I       +    + Y   EGK V++ C+   + S     +K + 
Sbjct: 379  ASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDT 438

Query: 968  SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST----MLVVKETI-----PE 1018
            S                        D G   C  K+ E S+    ML VK+       PE
Sbjct: 439  SDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPE 498

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK--KNKYDFEKRGHIRKLYI 1076
              R L+    +   +A  +   +++  +++WE+D + I     +N   F + G    L I
Sbjct: 499  DSRILKGTTAQFSCLAEYDKSFSNDF-EILWEKDDKEIAVNYTENSRYFVEDG---LLQI 554

Query: 1077 RNTSVHDEGEYSCILR----DESCTAEVTVVELP 1106
             N S  D+G Y+C+ R     +  TA + V+++P
Sbjct: 555  VNVSHLDKGVYTCLARTPMDGDKATALLLVIDVP 588



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 101/427 (23%), Positives = 177/427 (41%), Gaps = 41/427 (9%)

Query: 639  KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
            K +A+ V +G D+ LEC     P P + W+  G+ + P +     IES    +  +L + 
Sbjct: 224  KSEARLV-KGEDLNLECIAAGFPTPQVEWVKMGQRL-PTK---ATIES----HGKLLFVP 274

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
             V++   G Y   A N  GEA     + ++     PP+ +   +S +   G  V++   V
Sbjct: 275  TVEQEDGGKYMCKAKNTLGEAVHYFTVTVEG----PPEWVSEPESQLSMIGSDVLIKCSV 330

Query: 759  VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             G P+PT+TW  N   ++  P  +        +L   K  D  VY  +A N  G   ++A
Sbjct: 331  SGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNRHGTLLSNA 390

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
             I +      N  P +     ++ +  E   + +  +V  +P P+ITW +++   S    
Sbjct: 391  NIMI-----MNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGP 445

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938
                 D   +E  I   + E D+G Y C A N+ G S+  A   + V+  T +    +  
Sbjct: 446  RFSVHDNGTLE--IYRAEKE-DAGPYTCFAKNTEGSSAINA--MLSVKDPTRIVEPPEDS 500

Query: 939  ETEEGKTVILECQTSHTVSTK------WYHNKKEIS---GMDHREIIQEGRXXXXXXXXX 989
               +G T    C   +  S        W  + KEI+     + R  +++G          
Sbjct: 501  RILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDG---LLQIVNV 557

Query: 990  XXXDVGVIKCIVK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV---EINSE 1043
               D GV  C+ +   D + +T L++   +P+  + L   E K K V +  +   + NS 
Sbjct: 558  SHLDKGVYTCLARTPMDGDKATALLLVIDVPDAPQYLVLSEHKSKSVKLKWIPGDDHNSS 617

Query: 1044 TADVVWE 1050
            T + + E
Sbjct: 618  TTEFIIE 624



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 57/193 (29%), Positives = 82/193 (42%), Gaps = 11/193 (5%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX-XXXXXXXXXYKCIAFND 1555
            ED+ L CI  G P P+V W + G++L T KAT E+                 Y C A N 
Sbjct: 233  EDLNLECIAAGFPTPQVEWVKMGQRLPT-KATIESHGKLLFVPTVEQEDGGKYMCKAKNT 291

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
             GE      V ++  P     +E   Q   +G + L+   + G P P V W  NGN+L++
Sbjct: 292  LGEAVHYFTVTVEGPPEWV--SEPESQLSMIGSDVLIKCSVSGTPQPTVTWRVNGNRLQD 349

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675
                N      T V+     K S S+ Y  EASN  GT      + + + P     P+I+
Sbjct: 350  SPAPNRRVLGDTIVLH--NTKPSDSAVYQCEASNRHGTLLSNANIMIMNFP-----PMIL 402

Query: 1676 REISRESVTIEWK 1688
             E   +   +E K
Sbjct: 403  TENDEDYSAVEGK 415



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 122/607 (20%), Positives = 220/607 (36%), Gaps = 42/607 (6%)

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            E R+ +G D+ L      FP P  EW+   + +     TK +I+S    L +  VE  D 
Sbjct: 226  EARLVKGEDLNLECIAAGFPTPQVEWVKMGQRLP----TKATIESHGKLLFVPTVEQEDG 281

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSSSINICWDEPENTGNSTII 1413
            G Y  + +N  G A     VT+   P    +P   +  I S  +  C      T   T+ 
Sbjct: 282  GKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIGSDVLIKC--SVSGTPQPTVT 339

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            + V   +  D+      + +      + N K + S      AV + + S+   T      
Sbjct: 340  WRVNGNRLQDSP--APNRRVLGDTIVLHNTKPSDS------AVYQCEASNRHGTLLSNAN 391

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD--GKKLKTAKATYEN 1531
            I         + +  ++ +    + + + C     P P +TW +D     +   + +  +
Sbjct: 392  IMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHD 451

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C A N  G    + ++ ++    I    ED +       ++ 
Sbjct: 452  NGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFS 511

Query: 1592 VTAVIEG--IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
              A  +       E++W K+  ++  +   N     +  +++I  +       YT  A  
Sbjct: 512  CLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLART 571

Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP- 1708
                      L V D P  P+  +++ E   +SV ++W P  DD     T++ IE  E  
Sbjct: 572  PMDGDKATALLLVIDVPDAPQ-YLVLSEHKSKSVKLKWIPG-DDHNSSTTEFIIEYEESQ 629

Query: 1709 -DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDV 1766
             +   W ++  V  +     I KL+ + +Y FRV   N VG      S+P    +T    
Sbjct: 630  REPGNWKELLRVPGN-HNSAILKLHGHVDYCFRVSGVNAVG--RGPSSQPTERYRTPPAA 686

Query: 1767 PSXXXXXXXXXXIDNESVYITW---FPSEKNGGSPIIDYKVEIKQEG--KKWKXXXXXXX 1821
            P                + I W    P E+NG  P ++YKV  +++   + W+       
Sbjct: 687  PDKNPENIKIESHLPHEMDINWEPLLPIEQNG--PGLEYKVSYRRQDVEEDWQEHIVKRH 744

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTS 1879
                ++       Y+ +I ARN  G    +  + +I  G +    P + P +  V    S
Sbjct: 745  SFV-VKNTPTFVPYEIKIQARNHQG----WGPEPRIATGYSGEDFPSAAPDDVAVEVINS 799

Query: 1880 RSVTLKW 1886
              V + W
Sbjct: 800  SVVKVSW 806



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 101/505 (20%), Positives = 185/505 (36%), Gaps = 36/505 (7%)

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX--XXXXXYKCIAFND 1555
            D+ + C   G PQP VTW  +G +L+ + A                      Y+C A N 
Sbjct: 323  DVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNR 382

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            HG + ++  + I   P + ++  D       G   ++   +   P P + W K+      
Sbjct: 383  HGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSV 442

Query: 1616 D-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
            D   +++        + I   ++  +  YT  A NT G+S++   L V D     E P  
Sbjct: 443  DGPRFSV---HDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPED 499

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR-DVETYCIQKLNE 1733
             R +  +  T ++    +        + I   + D    +   +  R  VE   +Q +N 
Sbjct: 500  SRIL--KGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNV 557

Query: 1734 N--CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
            +   + ++  +A+ P+   +A       +   +DVP             ++SV + W P 
Sbjct: 558  SHLDKGVYTCLARTPMDGDKA-----TALLLVIDVPDAPQYLVLSEH-KSKSVKLKWIPG 611

Query: 1792 EKNGGSP---IIDYKVEIKQEGKKWKXXXXX-XXXXARIQKLSINTTYQFRIYARNEIGT 1847
            + +  S    II+Y+ E ++E   WK          + I KL  +  Y FR+   N +G 
Sbjct: 612  DDHNSSTTEFIIEYE-ESQREPGNWKELLRVPGNHNSAILKLHGHVDYCFRVSGVNAVGR 670

Query: 1848 SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----ESNGGSPITNYIIE 1903
              P +   +        P   P N  +       + + W EP    E NG  P   Y + 
Sbjct: 671  G-PSSQPTERYRTPPAAPDKNPENIKIESHLPHEMDINW-EPLLPIEQNG--PGLEYKVS 726

Query: 1904 FKTVK-GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            ++     + W + +      H   ++N         +I A N  G     E +       
Sbjct: 727  YRRQDVEEDWQEHIV---KRHSFVVKNTPTFVPYEIKIQARNHQGWG--PEPRIATGYSG 781

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSW 1987
               PS     + + ++ S++V  SW
Sbjct: 782  EDFPSAAPDDVAVEVINSSVVKVSW 806



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 3/81 (3%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G  V   C+V   P P ITW +       S D   +   DN  TL I     EDAG +T
Sbjct: 413 EGKRVMMHCKVFSSPSPTITWSKDDT--SDSVDGPRFSVHDN-GTLEIYRAEKEDAGPYT 469

Query: 583 CVAKNAAGFASSTTELIVEAP 603
           C AKN  G ++    L V+ P
Sbjct: 470 CFAKNTEGSSAINAMLSVKDP 490



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 64/300 (21%), Positives = 117/300 (39%), Gaps = 27/300 (9%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVE 1192
            V W K G  +      + TI+   + L +   + +D G+Y C+  N+   A+    +TVE
Sbjct: 249  VEWVKMGQRLP----TKATIESHGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVE 304

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVK 1249
             P     +  PE  L    +D  +   +   P  T  VTW    + ++D+        V 
Sbjct: 305  GPP--EWVSEPESQLSMIGSDVLIKCSVSGTPQPT--VTWRVNGNRLQDSPAPN--RRVL 358

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIV-DYEREYRIKRGSDVT 1306
              T+++      D   Y C   +   T  +   + ++ FPP I+ + + +Y    G  V 
Sbjct: 359  GDTIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVM 418

Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENN 1365
            +     + P P   W   SK         P      + +L I + E  DAG Y    +N 
Sbjct: 419  MHCKVFSSPSPTITW---SKDDTSDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNT 475

Query: 1366 CGHADVEMNVTILDKP---SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422
             G + +   +++ D      PP    IL+  ++  +   +  ++  N   I +  + +EI
Sbjct: 476  EGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEI 535



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC   G+P PQ+ W +    +           + +   L +  V  ED G + C
Sbjct: 232 GEDLNLECIAAGFPTPQVEWVKMGQRLPTKATI-----ESHGKLLFVPTVEQEDGGKYMC 286

Query: 584 VAKNAAGFASSTTELIVEAP 603
            AKN  G A     + VE P
Sbjct: 287 KAKNTLGEAVHYFTVTVEGP 306



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V  +C V G P+P +TW      ++ S         D   T+V+    P D+  + C
Sbjct: 321 GSDVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGD---TIVLHNTKPSDSAVYQC 377

Query: 584 VAKNAAGFASSTTELIV 600
            A N  G   S   +++
Sbjct: 378 EASNRHGTLLSNANIMI 394



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 12/132 (9%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCT----AEVTVVELPPEIITRL-QNQKVNKGNKATFEI 1128
            + + NT   D   Y C   +   T    A + ++  PP I+T   ++    +G +     
Sbjct: 362  IVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHC 421

Query: 1129 ELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183
            ++    +  + W KD +            D     L+IY  + +DAG Y+C      G+S
Sbjct: 422  KVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGT--LEIYRAEKEDAGPYTCFAKNTEGSS 479

Query: 1184 KCTAILTVEEPS 1195
               A+L+V++P+
Sbjct: 480  AINAMLSVKDPT 491



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 8/113 (7%)

Query: 1567 IQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
            +Q++P ++T      + +   G++  +  +  G P P+V W K G +L        T + 
Sbjct: 211  LQRRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKMGQRLPT----KATIES 266

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVIM 1675
               ++ +  +++    KY  +A NT G +    T+ V   P   S+PE  + M
Sbjct: 267  HGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSM 319


>UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA,
            isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG13521-PA, isoform A - Tribolium castaneum
          Length = 1073

 Score =  100 bits (240), Expect = 4e-19
 Identities = 128/526 (24%), Positives = 204/526 (38%), Gaps = 44/526 (8%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD--------GDT 786
            P++ E    +IV + E V L+ +  G P PTI W K+ +PVK  PT +         G  
Sbjct: 19   PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78

Query: 787  HSITILKPKKVKDEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEITVK 845
              +  +  KK +D GVY   A N+ G A   +A + V    +E    P       +  V 
Sbjct: 79   FFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMP------SDTRVA 132

Query: 846  EKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904
               T  L     R +P P++ W ++ E++       +  DG N  L+I++V  + D G Y
Sbjct: 133  AGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVDGGN--LMISDV-RQHDEGRY 189

Query: 905  KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTKWYHN 963
            +CVA N  G S     V + V    F     +      GK V+ +C      V    +  
Sbjct: 190  QCVAHNLVG-SRETPPVMLTVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWRR 248

Query: 964  KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020
            +     +    I+ +              D G+  C  ++     T+   +V  + P FI
Sbjct: 249  EDGKMPIGRARILDD---KSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFI 305

Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRN 1078
             K +D +V    V         +    V W ++G +++    N Y          L I+ 
Sbjct: 306  EKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365

Query: 1079 TSVHDEGEYSC----ILRDESCTA--EVT-VVELPPEII-TRLQNQKVNKGNKATFEIEL 1130
                D G   C    +    S  A  +VT V +LPP II     NQ +   +  T   + 
Sbjct: 366  VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425

Query: 1131 TKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183
            +  +     +RW KDG  +Q           +   L I D  LDD+G Y+C    E G S
Sbjct: 426  SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
              +A L+V E S     R P+    P   +    +   + ++ + W
Sbjct: 486  SWSASLSVVEGSSALLHRSPDPSTFPKAPNQPRILNATESSITLAW 531



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 109/531 (20%), Positives = 202/531 (38%), Gaps = 54/531 (10%)

Query: 993  DVGVIKCIVKDQETSTM-----LVVKETIPEFIRKLQDFEVKEKDVAILEVEI--NSETA 1045
            D GV  C+ ++   S +     L V     EF     D  V   + A+L+          
Sbjct: 91   DAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETALLQCGAPRGHPEP 150

Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VT 1101
            +++W +DGE+++    +      G+   L I +   HDEG Y C+  +   + E    + 
Sbjct: 151  NLMWRKDGEVLEVDGRRIRIVDGGN---LMISDVRQHDEGRYQCVAHNLVGSRETPPVML 207

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159
             V + P      Q+     G +  F+  +  G+ +  V W ++  ++         +D K
Sbjct: 208  TVHVKPFFNKEPQDVVALLGKRVVFQCAVD-GEPVPNVLWRREDGKMPIGR--ARILDDK 264

Query: 1160 KQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215
               L I +    D G Y C     VG+    A L V  P         + + +    + +
Sbjct: 265  S--LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEKPRDQKVSLNGVVEFH 322

Query: 1216 LTVEIPDETLDVTWYKKKS--VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
             +    +    V W K+ S  ++     +  +      TL I+    +D     C  L  
Sbjct: 323  CSAT-GNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQGVQREDAGFLVCSALSV 381

Query: 1274 KSTTKLKV-----EVVEFPPKIVDY-EREYRIKRGSDVTLLVDYQA--FPQPNDEWIVNS 1325
              ++ ++       V + PP I+        +   S VTL     +    QP   W  + 
Sbjct: 382  AGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKASSPEGEQPKIRWSKDG 441

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD------ 1379
            K++++ +       S++ +L I  +   D+G+Y     +  G +    ++++++      
Sbjct: 442  KVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGESSWSASLSVVEGSSALL 501

Query: 1380 --KPSP------PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID-TTEWISV 1430
               P P      P +P IL    SSI + WD+    G   ++ Y VEY   D  T W+  
Sbjct: 502  HRSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAG---LVGYTVEYWSPDLQTGWVIA 558

Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481
             +       ++ LK +SSY F   A N   +S AS  +   + +  ++  S
Sbjct: 559  AHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSSIARTLANSRAVS 609



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 91/397 (22%), Positives = 150/397 (37%), Gaps = 53/397 (13%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDNVATL-VIREVFPEDAGTF 581
           V   C+ EG P P I WF+    +K S    +  ++     ++  L  +     +DAG +
Sbjct: 36  VTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSLFFLRTMNSKKEQDAGVY 95

Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
            CVA+N AG A S    +  A L D   E  V            A +L+   P    +P 
Sbjct: 96  WCVARNTAGSAVSRNATLQVAVLRD---EFRVMPSDTRVAAGETA-LLQCGAPRGHPEPN 151

Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
             +  +G  + ++ R +               IV   N+ +   SD+  +       +  
Sbjct: 152 LMWRKDGEVLEVDGRRI--------------RIVDGGNLMI---SDVRQH-------DEG 187

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
           ++Q   + +V         L + +K     KEP  V+  L       G+ V+    V G 
Sbjct: 188 RYQCVAHNLVGSRETPPVMLTVHVK-PFFNKEPQDVVALL-------GKRVVFQCAVDGE 239

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
           P P + W + +  +     +   D     ++   +  DEG+Y   AEN  G     A + 
Sbjct: 240 PVPNVLWRREDGKMPIGRARILDD--KSLLIDNVQTSDEGIYICAAENVVGSITAKASLV 297

Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--IISPSETI 879
           V         PP FI + ++  V   G ++     T NP PS+ W +     ++ P  + 
Sbjct: 298 VN-------SPPTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSY 350

Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
                  +  L I  V  E D+G   C A + AG SS
Sbjct: 351 GHMHVNAHGTLRIQGVQRE-DAGFLVCSALSVAGSSS 386



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 161/824 (19%), Positives = 291/824 (35%), Gaps = 78/824 (9%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASL 1345
            P+I ++  +  + +   VTL    +  P+P  EW  + + +K       S  +   + SL
Sbjct: 19   PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78

Query: 1346 ----TIKKVENTDAGIYKLRLENNCGHA---DVEMNVTIL-DKPSPPGKPNILEIDSSSI 1397
                T+   +  DAG+Y     N  G A   +  + V +L D+         +    +++
Sbjct: 79   FFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETAL 138

Query: 1398 NICWDEPENTGNSTIIYYVV-EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
              C   P       +++    E  E+D      ++ +      I +++ +   R++  A 
Sbjct: 139  LQC-GAPRGHPEPNLMWRKDGEVLEVDGRR---IRIVDGGNLMISDVRQHDEGRYQCVAH 194

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            N V     S  T    +    K   P   K  +++     + +   C   G P P V W 
Sbjct: 195  NLV----GSRETPPVMLTVHVK---PFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWR 247

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576
            R+  K+   +A   +                Y C A N  G +     + +   P     
Sbjct: 248  REDGKMPIGRARILDDKSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEK 307

Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK--LENDKEYNITTKEKTSVIRIKE 1634
              D K       E+  +A   G PPP V W K G++  +  D  Y          +RI+ 
Sbjct: 308  PRDQKVSLNGVVEFHCSAT--GNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-----GPVIMREISRESVTIEWKP 1689
            ++R  +      A + AG+SSV   L+V      P      GP          VT+  K 
Sbjct: 366  VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425

Query: 1690 PLDDGGLELTKYA------IEKHEPDNNRWIKVADVD------RDVETYCIQKLNENCEY 1737
               +G     +++       E+  PD     +   +D       D   Y    ++E+ E 
Sbjct: 426  SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             +        G S  L   P    T    P+              S+ + W    + G  
Sbjct: 486  SWSASLSVVEGSSALLHRSPDP-STFPKAPNQPRILNAT----ESSITLAWDDGPEAG-- 538

Query: 1798 PIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS--LPYTS 1853
             ++ Y VE      +  W            +++L  +++Y F + A N  G S   P +S
Sbjct: 539  -LVGYTVEYWSPDLQTGWVIAAHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSS 597

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT------NYI----IE 1903
              + T+  +        +   +  +++ V L+   P+S+    +T      +YI    I 
Sbjct: 598  IAR-TLANSRAVSGSELDTARTALSTKLVELRDARPQSSSSVKLTWSLAALDYIEGLYIR 656

Query: 1904 FKTVKGKSWT-KIVTV-GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            F+ + G S    I+TV       + + N+K+  +  F I+         P+ S+  +  +
Sbjct: 657  FRELSGGSHNYNILTVLDVQTKSYTVSNLKKFTKYEFFIAPFYKSVEGQPSNSRVAQTLE 716

Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019
               VPS P   +   +         W   P       ++GY I IR  +T+++      V
Sbjct: 717  --DVPSAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRGSITRSL-----TV 769

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
            + +T    I +L+   +Y  RI A    G   P  +  P    P
Sbjct: 770  NSSTTSVLISNLTSGGSYNARIAALTHAG-QGPYSNQVPLLTAP 812



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 64/298 (21%), Positives = 115/298 (38%), Gaps = 21/298 (7%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           + P F+K+P+      G  ++ +C +   P P++ W  + +  +P     +  +      
Sbjct: 211 VKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWR-REDGKMPIGRARILDDKS---- 265

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              L I NV+   EG Y   A N  G  +    L + +    PP  IE  +   V     
Sbjct: 266 ---LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNS----PPTFIEKPRDQKVSLNGV 318

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKA 807
           V       GNP P++ W K    +   P  S G    + H    ++  + +D G     A
Sbjct: 319 VEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQGVQREDAGFLVCSA 378

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNPVPSIT 865
            +  G +   A + V    +    PP+       Q + +    T+   A       P I 
Sbjct: 379 LSVAGSSSVRAFLQVTSVAD--LPPPIIQIGPANQTLPLHSMVTLHCKASSPEGEQPKIR 436

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           W ++ +++       +    E   L I ++  + DSG Y C A + +G+SS  A +++
Sbjct: 437 WSKDGKVLQEERLPDRYTISETGTLDIDDLRLD-DSGLYTCSAISESGESSWSASLSV 493



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 77/307 (25%), Positives = 124/307 (40%), Gaps = 27/307 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENIS--VAIESDMH 689
           P  ++ P    V +   + L C+    PEP I W   GE +   P +N S  V + +   
Sbjct: 19  PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78

Query: 690 MYCSVLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            +   L+  N KK Q+ G Y  VA N  G A S    L++     E   +    +   V 
Sbjct: 79  FF---LRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTR---VA 132

Query: 748 QGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            GE+ +L      G+P P + W K+ + ++    +         ++   +  DEG Y   
Sbjct: 133 AGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVDGGNLMISDVRQHDEGRYQCV 192

Query: 807 AENSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           A N  G  ET  V +TV      N EP       Q++       +     V   PVP++ 
Sbjct: 193 AHNLVGSRETPPVMLTVHVKPFFNKEP-------QDVVALLGKRVVFQCAVDGEPVPNVL 245

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W R +  +       +  D ++  L+I NV +  D G Y C A N  G  +  A + ++ 
Sbjct: 246 WRREDGKMPIGR--ARILDDKS--LLIDNVQTS-DEGIYICAAENVVGSITAKASLVVN- 299

Query: 926 EKVTFVK 932
              TF++
Sbjct: 300 SPPTFIE 306



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 48/207 (23%), Positives = 91/207 (43%), Gaps = 13/207 (6%)

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVA 683
           A ++   PPTF +KP+ Q V     +   C     P P + W  +G +++  PD +    
Sbjct: 294 ASLVVNSPPTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSY--- 350

Query: 684 IESDMHMYC-SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--P 740
               MH+     L+I  V++   G     A++  G +S+   L++ +    PP +I+  P
Sbjct: 351 --GHMHVNAHGTLRIQGVQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGP 408

Query: 741 L-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKV 797
             +++ +    ++   A      +P I W K+ K +  + LP +          +   ++
Sbjct: 409 ANQTLPLHSMVTLHCKASSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRL 468

Query: 798 KDEGVYTLKAENSEGIAETSAVITVEE 824
            D G+YT  A +  G +  SA ++V E
Sbjct: 469 DDSGLYTCSAISESGESSWSASLSVVE 495



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 162/807 (20%), Positives = 288/807 (35%), Gaps = 78/807 (9%)

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS-----NHIQLTI 1156
            + E P +II   +N+ V    KA    E T     + WFKDG  ++ S     +H  L  
Sbjct: 21   ITEHPSDIIVA-KNEPVTLNCKAEGRPEPT-----IEWFKDGEPVKTSPTDNKSHRVLLP 74

Query: 1157 DGKKQKLKIYDCDLD-DAGEYSCEVGNSKCTAI---LTVEEPSINFTLR-LPEFILVPAN 1211
             G    L+  +   + DAG Y C   N+  +A+    T++   +    R +P    V A 
Sbjct: 75   AGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAG 134

Query: 1212 TDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              A L    P      ++ W K   V+E   +   I D     L+I    + D+  Y CV
Sbjct: 135  ETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVD--GGNLMISDVRQHDEGRYQCV 192

Query: 1270 ---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
               L+ ++ T  + +  V   P      ++     G  V         P PN  W    +
Sbjct: 193  AHNLVGSRETPPVML-TVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLW--RRE 249

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386
              K        +D KS  L I  V+ +D GIY    EN  G    + ++ +   P+   K
Sbjct: 250  DGKMPIGRARILDDKS--LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEK 307

Query: 1387 PNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445
            P   ++  S   +       TGN    +++  E  ++      S  ++         ++ 
Sbjct: 308  PRDQKV--SLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505
                       + + ++ +S    + +V     +  P ++    N T   +  + L C  
Sbjct: 366  VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425

Query: 1506 GGV--PQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGE- 1558
                  QPK+ W +DGK L+  +     T                   Y C A ++ GE 
Sbjct: 426  SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485

Query: 1559 --------VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-N 1609
                    VE S  +  +     T      + +     E  +T   +  P   ++ Y   
Sbjct: 486  SWSASLSVVEGSSALLHRSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAGLVGYTVE 545

Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663
                +    + I     ++ I ++ELK   S  + + A N  G       SS+  TL   
Sbjct: 546  YWSPDLQTGWVIAAHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSSIARTLANS 605

Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD--- 1720
               S  E       +S + V +    P     ++LT +++   +     +I+  ++    
Sbjct: 606  RAVSGSELDTARTALSTKLVELRDARPQSSSSVKLT-WSLAALDYIEGLYIRFRELSGGS 664

Query: 1721 --------RDVET--YCIQKLNENCEYMFRVIAQNPVGFSEALESEPI---VIKTALDVP 1767
                     DV+T  Y +  L +  +Y F +       F +++E +P    V +T  DVP
Sbjct: 665  HNYNILTVLDVQTKSYTVSNLKKFTKYEFFI-----APFYKSVEGQPSNSRVAQTLEDVP 719

Query: 1768 SXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826
            S           ++ + ++ W  P  ++    II YK++I+    +             I
Sbjct: 720  SAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRGSITR-SLTVNSSTTSVLI 778

Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTS 1853
              L+   +Y  RI A    G   PY++
Sbjct: 779  SNLTSGGSYNARIAALTHAGQG-PYSN 804



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 45/216 (20%), Positives = 90/216 (41%), Gaps = 18/216 (8%)

Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
            +E  + +  + +++ +SP + +   +I    NE + L C   G P+P + W++DG+ +KT
Sbjct: 2    AECEKSWAQLNDSQFRSPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKT 61

Query: 1525 AKATYENR----------XXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQ-QKPV 1572
            +    ++                          Y C+A N  G  V  +  + +   +  
Sbjct: 62   SPTDNKSHRVLLPAGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDE 121

Query: 1573 ITISNEDIKQKHKVGDEWLV-TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
              +   D +     G+  L+      G P P ++W K+G  LE D    I   +  +++ 
Sbjct: 122  FRVMPSDTRV--AAGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGR-RIRIVDGGNLM- 177

Query: 1632 IKELKRSHSSKYTIEASNTAGT-SSVEVTLKVYDKP 1666
            I ++++    +Y   A N  G+  +  V L V+ KP
Sbjct: 178  ISDVRQHDEGRYQCVAHNLVGSRETPPVMLTVHVKP 213



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVAT 567
           P F+EK R +       V+F C   G P P + W ++ +  ++ P   +   + + +  T
Sbjct: 302 PTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAH-GT 360

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593
           L I+ V  EDAG   C A + AG +S
Sbjct: 361 LRIQGVQREDAGFLVCSALSVAGSSS 386



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V F+C V+G P P + W R+   +   +      DD +   L+I  V   D G + C
Sbjct: 227 GKRVVFQCAVDGEPVPNVLWRREDGKMPIGR--ARILDDKS---LLIDNVQTSDEGIYIC 281

Query: 584 VAKNAAGFASSTTELIVEAP 603
            A+N  G  ++   L+V +P
Sbjct: 282 AAENVVGSITAKASLVVNSP 301


>UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-Mlck
            CG18255-PA, isoform A; n=2; Coelomata|Rep: PREDICTED:
            similar to Stretchin-Mlck CG18255-PA, isoform A - Apis
            mellifera
          Length = 3978

 Score =  100 bits (239), Expect = 5e-19
 Identities = 104/443 (23%), Positives = 181/443 (40%), Gaps = 46/443 (10%)

Query: 496  PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555
            P+ +K    E+   P F  +L  +    G   +  C V G+P P++ W +    +  + +
Sbjct: 3445 PIKDKLAPREKGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTN 3504

Query: 556  FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615
                  D+ +A   + E  PED+G +TCVA+N  G AS+ + L V        S  T   
Sbjct: 3505 KYKTRFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTR 3564

Query: 616  XXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675
                         + G    + +     Y    ++++LECR+   P P I+WL  G  + 
Sbjct: 3565 S------------IRG----YIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILR 3608

Query: 676  PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--REGEASLPIVLK------I 727
             D      ++  ++     L+I   K    G YT  A+N  R  E S  +         +
Sbjct: 3609 GDRYKQSYLDDGIYR----LEIAAPKSTDNGRYTCRAMNDLRTEEISHIVQFNERDRRIV 3664

Query: 728  KTGEK-----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--P 774
               EK           + P+    L    V  G ++ L  +V G P P + W +  +  P
Sbjct: 3665 NKHEKLFDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREP 3724

Query: 775  VKALPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTE-ENAEP 832
            V     K+  ++   T++ P+  + E G Y  +A N+ G  ++ A + V  P+  +  +P
Sbjct: 3725 VSIPKAKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKP 3784

Query: 833  PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
             +F++R  E  ITV     + +  RVT  P P +TW +  + I+      +    + + L
Sbjct: 3785 AMFVSRPSEKSITVNSGEDVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDYVRL 3844

Query: 891  VITNVDSEIDSGDYKCVASNSAG 913
             +  V +  D G Y  +  N  G
Sbjct: 3845 TLKRVVA-TDEGTYCILVKNRYG 3866



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 81/305 (26%), Positives = 122/305 (40%), Gaps = 23/305 (7%)

Query: 530  ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
            EC+V G P P I+W +   I++  + ++  Y DD +  L I      D G +TC A N  
Sbjct: 3587 ECRVRGNPTPVISWLKDGCILRGDR-YKQSYLDDGIYRLEIAAPKSTDNGRYTCRAMN-- 3643

Query: 590  GFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS 649
                  TE I      +      V             +  +   P FS       V  G 
Sbjct: 3644 ---DLRTEEISHIVQFNERDRRIVNKHEKLFDDYFSLETYKR--PRFSSYLSDYSVPTGG 3698

Query: 650  DILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
             I L+  +  +P P++ W F+GE  E V         ES +H     L +  V + ++GT
Sbjct: 3699 TIALQVEVKGVPAPEVRW-FRGERREPVSIPKAKTFTESGVH----TLVLPEVTESEKGT 3753

Query: 708  YTVVAVNREGEASLPIVLKIKT-----GEKEPPQVIEPL-KSMIVRQGESVILSAQVVGN 761
            Y   A+N  G       +++ +     G K    V  P  KS+ V  GE V +S +V G 
Sbjct: 3754 YICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVSRPSEKSITVNSGEDVSVSFRVTGI 3813

Query: 762  PRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
            P+P +TW K  K +       K   D +    LK     DEG Y +  +N  G   +   
Sbjct: 3814 PKPRVTWMKGLKDITDGLRSHKETIDDYVRLTLKRVVATDEGTYCILVKNRYGCDRSFFS 3873

Query: 820  ITVEE 824
            I V++
Sbjct: 3874 IKVKQ 3878



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 77/324 (23%), Positives = 123/324 (37%), Gaps = 35/324 (10%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDM 688
            +G  P+F  +   + V  G    L C ++  PEP + W   GE++ +         ++ M
Sbjct: 3455 KGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKTRFDNGM 3514

Query: 689  HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMI 745
              +    ++        G YT VA N  G AS    LK+    +    PP     ++  I
Sbjct: 3515 AYF----ELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTRSIRGYI 3570

Query: 746  ------VRQGES-VILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPK 795
                   R  ++ +IL  +V GNP P I+W K+   ++    K    D   + + I  PK
Sbjct: 3571 RFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRGDRYKQSYLDDGIYRLEIAAPK 3630

Query: 796  KVKDEGVYTLKAENSEGIAETSAVITVEEPTE----------------ENAEPPLFINRF 839
               D G YT +A N     E S ++   E                   E  + P F +  
Sbjct: 3631 ST-DNGRYTCRAMNDLRTEEISHIVQFNERDRRIVNKHEKLFDDYFSLETYKRPRFSSYL 3689

Query: 840  QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
             + +V   GTI L   V   P P + W+R       S    + F    +  ++    +E 
Sbjct: 3690 SDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLVLPEVTES 3749

Query: 900  DSGDYKCVASNSAGKSSHGARVTI 923
            + G Y C A N+ G     A V +
Sbjct: 3750 EKGTYICRAINAYGHVDSIATVEV 3773



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 64/234 (27%), Positives = 99/234 (42%), Gaps = 30/234 (12%)

Query: 486  KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
            +++  K +KL  F+   S E    P F   L     P G T+  + +V+G P P++ WFR
Sbjct: 3661 RRIVNKHEKL--FDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFR 3718

Query: 546  QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605
                   S      + +  V TLV+ EV   + GT+ C A NA G   S   + V +P +
Sbjct: 3719 GERREPVSIPKAKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSA 3778

Query: 606  DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP--KAQYVDEGSDILLECRLVAIPEP 663
              G                      G P  F  +P  K+  V+ G D+ +  R+  IP+P
Sbjct: 3779 IDG----------------------GKPAMFVSRPSEKSITVNSGEDVSVSFRVTGIPKP 3816

Query: 664  DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
             + W+ KG + + D   S     D ++    L +  V    EGTY ++  NR G
Sbjct: 3817 RVTWM-KGLKDITDGLRSHKETIDDYVR---LTLKRVVATDEGTYCILVKNRYG 3866



 Score = 50.4 bits (115), Expect = 5e-04
 Identities = 47/202 (23%), Positives = 72/202 (35%), Gaps = 17/202 (8%)

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
            K+    K + P+    L N T        LTC   G P+P+V W +DG+KL      Y+ 
Sbjct: 3449 KLAPREKGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKT 3508

Query: 1532 RXXXXXXXXXX-----XXXXXYKCIAFNDHGEVETSCVVGIQ-------QKPVITISNED 1579
            R                    Y C+A N HG   T   + +          P  T S   
Sbjct: 3509 RFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTRSIRG 3568

Query: 1580 ----IKQKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
                    ++  D E ++   + G P P + W K+G  L  D+       +    + I  
Sbjct: 3569 YIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRGDRYKQSYLDDGIYRLEIAA 3628

Query: 1635 LKRSHSSKYTIEASNTAGTSSV 1656
             K + + +YT  A N   T  +
Sbjct: 3629 PKSTDNGRYTCRAMNDLRTEEI 3650



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            VG +  +T  + G P P V W K+G KL+    +Y        +   + E     S  YT
Sbjct: 3472 VGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKTRFDNGMAYFELHEPLPEDSGLYT 3531

Query: 1645 IEASNTAGTSSVEVTLKVY 1663
              A N  G +S E  LKVY
Sbjct: 3532 CVAENVHGIASTESALKVY 3550



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 80/378 (21%), Positives = 135/378 (35%), Gaps = 58/378 (15%)

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102
            V W +DGE +    NKY       +    +      D G Y+C+  +     S  + + V
Sbjct: 3490 VYWTKDGEKLDITTNKYKTRFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKV 3549

Query: 1103 VE-----LPPEIITRLQNQKV--------NKGNKATFEIELTKGDA-LVRWFKDGSEIQF 1148
                   L P   TR     +        +  N+   E  +      ++ W KDG  ++ 
Sbjct: 3550 YPDFQPTLSPPTFTRSIRGYIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRG 3609

Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA--------------ILTVEEP 1194
              + Q  +D    +L+I      D G Y+C   N   T               I+   E 
Sbjct: 3610 DRYKQSYLDDGIYRLEIAAPKSTDNGRYTCRAMNDLRTEEISHIVQFNERDRRIVNKHEK 3669

Query: 1195 SIN--FTL---RLPEF------ILVPANTDAYLTVEIPDETL-DVTWYK-KKSVIEDTEK 1241
              +  F+L   + P F        VP      L VE+      +V W++ ++       K
Sbjct: 3670 LFDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPK 3729

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD--------- 1292
                ++    TL++ + TE ++  Y C  ++A         V    P  +D         
Sbjct: 3730 AKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVS 3789

Query: 1293 --YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKK 1349
               E+   +  G DV++       P+P   W+   K I    +  K +ID     LT+K+
Sbjct: 3790 RPSEKSITVNSGEDVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDY-VRLTLKR 3848

Query: 1350 VENTDAGIYKLRLENNCG 1367
            V  TD G Y + ++N  G
Sbjct: 3849 VVATDEGTYCILVKNRYG 3866



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 42/194 (21%), Positives = 70/194 (36%), Gaps = 13/194 (6%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXX 1537
            P     L + +      I L     GVP P+V W+R  ++    +  AK   E+      
Sbjct: 3683 PRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLV 3742

Query: 1538 X-XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQ-KHKVGD 1588
                       Y C A N +G V++   V +         KP + +S    K      G+
Sbjct: 3743 LPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVSRPSEKSITVNSGE 3802

Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
            +  V+  + GIP P V W K    + +    +  T +    + +K +  +    Y I   
Sbjct: 3803 DVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDYVRLTLKRVVATDEGTYCILVK 3862

Query: 1649 NTAGTSSVEVTLKV 1662
            N  G      ++KV
Sbjct: 3863 NRYGCDRSFFSIKV 3876



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/102 (23%), Positives = 40/102 (39%), Gaps = 2/102 (1%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLT 1346
            P+   Y  +Y +  G  + L V+ +  P P   W    +         K   +S   +L 
Sbjct: 3683 PRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLV 3742

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKP 1387
            + +V  ++ G Y  R  N  GH D    V ++   +   GKP
Sbjct: 3743 LPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKP 3784


>UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep:
            CG33274-PB - Drosophila melanogaster (Fruit fly)
          Length = 1876

 Score =  100 bits (239), Expect = 5e-19
 Identities = 173/848 (20%), Positives = 320/848 (37%), Gaps = 81/848 (9%)

Query: 707  TYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV------ 759
            +YT   VNR  GE  +      +    EP  +++P  ++       V+L+ Q        
Sbjct: 64   SYTCRTVNRLTGEVQIS-TYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTTLPCIAQ 122

Query: 760  GNPRPTITWCKN-NKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAET 816
            G+P PT  W K  N+ +  L         S  +LK  K +  D G Y     N+ G    
Sbjct: 123  GHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEETI 182

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
               +TV  P   + +P +     Q + V +    + +  V+ +PV  + W  + + I   
Sbjct: 183  QVSLTVTAPLTAHLQPQV-----QTVDVDKDAQFQCI--VSGHPVHDVNWLHDGKPILRD 235

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
              +    D     L+I  V  E D G Y+C  SN   +    A + +       +    +
Sbjct: 236  NRVEILTDPPR--LIIKKVQKE-DPGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSE 292

Query: 937  SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREI-------IQEGRXXXXXXXXX 989
                + G TV L+C  +     ++  +       D           I +           
Sbjct: 293  Q-TLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNV 351

Query: 990  XXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQDFEVKEKDVAILEVEINSETADV 1047
               D G   C  ++         K  I    +IR++           I++  +     D 
Sbjct: 352  KEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDK 411

Query: 1048 V-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL- 1105
            + WERDG+ +   + +  +     I +   R   + D G Y+C+ +++        VE+ 
Sbjct: 412  IHWERDGQTLPINRRQRAYNNGTLIIEQLQR---LEDAGTYTCMAQNKQKQTSRRNVEIQ 468

Query: 1106 ---PPEIIT-RLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSE-IQFSNHIQLTIDG 1158
               PP+I+  +     + +G +A    ++ +GD  V  RW ++G   I   N +   +D 
Sbjct: 469  VLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDE 528

Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218
                L I     D +G Y+C   N   T   TV   ++N     P++IL P ++ A    
Sbjct: 529  YSASLVIEHISSDHSGNYTCIASNVAGTERFTVPL-TVNVP---PKWILEPKDSSAQAGA 584

Query: 1219 EI-------PDETLDVTWYKKKSVIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYT 1267
            ++          T  +TW K         K  L     +     T+  +K +++ Q  + 
Sbjct: 585  DVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFL 644

Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325
            C   +      +K+    V  P       ++  + +G  V +  + Q     + +W + +
Sbjct: 645  CEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQA 704

Query: 1326 --KIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
              + + +   ++ +I      D   + L I      D GIY  +  N  G  ++ + + +
Sbjct: 705  TQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIV 764

Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--- 1434
             + P  P    I    S S+ + W +P   GNS I  Y + Y++I    W + +++T   
Sbjct: 765  QEVPEQPKNLRINSQQSRSLQLTWSQP-FAGNSPIEEYHIYYKQISDI-WQNAEHLTIAG 822

Query: 1435 -KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
             +T  +IQ L+   +Y  R  A N++  S+ SE      V++ T ++      PL  +  
Sbjct: 823  AQTVINIQQLRPAKAYHIRMSAENKLGASEFSE------VVQVTTLEEVPSGPPLA-VRA 875

Query: 1494 EPNEDIEL 1501
            EP    E+
Sbjct: 876  EPKSSTEI 883



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 185/908 (20%), Positives = 346/908 (38%), Gaps = 79/908 (8%)

Query: 638  KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
            +K   ++V       L C     P P   W  +  E +    +S  I     +   +LKI
Sbjct: 102  EKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFKEENEQLLPLQLSERITI---VSAGLLKI 158

Query: 698  TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
            T  +    G Y     N  GE ++ + L +          ++P +   V   +       
Sbjct: 159  TKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAH---LQP-QVQTVDVDKDAQFQCI 214

Query: 758  VVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816
            V G+P   + W  + KP+ +    +   D   + I K +K +D G+Y     N     ++
Sbjct: 215  VSGHPVHDVNWLHDGKPILRDNRVEILTDPPRLIIKKVQK-EDPGMYQCFVSNEWEQIQS 273

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            +A + + +     A P L +  F E T++   T+ L    T NP+P  TW  +   I  S
Sbjct: 274  TAELQLGD-----ASPEL-LYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDS 327

Query: 877  ETITQN-----FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931
                        D     + I+NV  E D G+Y C A N+ GK SH A+V  ++  + ++
Sbjct: 328  SRFLVGQYVTIHDDVISHVNISNVKEE-DGGEYTCTAQNAIGKVSHSAKV--NIYGLPYI 384

Query: 932  KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
            + + K      G  +I++C  +     K +  +   +   +R                  
Sbjct: 385  REMPK-ITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQRL 443

Query: 992  XDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFE--VKEKDVAILEVEINSETAD 1046
             D G   C+ ++++  T    + ++  +P  I  +Q     ++E   A +  +I      
Sbjct: 444  EDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLP 503

Query: 1047 VV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102
            V   WER+G+ +    N+       +   L I + S    G Y+CI  + + T   TV  
Sbjct: 504  VSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPL 563

Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK-------DGSEIQFSNHIQ 1153
             V +PP+ I   ++     G       + +      + W K       +  +  +   +Q
Sbjct: 564  TVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQ 623

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL---PEFILVPA 1210
            L  +G     KI     +  G + CE  N+  + +  V    +N         + I V  
Sbjct: 624  LFPNGTIFFKKI---SKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAK 680

Query: 1211 NTDAYLTVEIP-DETLDVTW--YKKKSVIEDT--EKFTL----ISDVKKRTLIIRKCTED 1261
                ++   +  D  +D  W     +  ++++   ++T+    + D     L I      
Sbjct: 681  GKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQ 740

Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFP--QPN 1318
            D   Y C   +A    ++ ++++    ++ +  +  RI      +L + + Q F    P 
Sbjct: 741  DTGIYICQASNAFGQDEMSIQLI--VQEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPI 798

Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVE--MN 1374
            +E+ +  K I         +    A   I   +   A  Y +R+  EN  G ++    + 
Sbjct: 799  EEYHIYYKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQ 858

Query: 1375 VTILDK-PS-PPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVK 1431
            VT L++ PS PP         S+ I + WD PE +  N  ++ Y V YQ   T E    K
Sbjct: 859  VTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPE---DK 915

Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491
             +  TQ    + KT      R++   E  +++ ++ T+Y+ +++    Q      P K I
Sbjct: 916  EVNPTQGF--SFKT---VEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGS--GPPSKEI 968

Query: 1492 TTEPNEDI 1499
              +  ED+
Sbjct: 969  AVQTMEDV 976



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 206/986 (20%), Positives = 365/986 (37%), Gaps = 89/986 (9%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130
            L I    + D G+Y C + + +    + V   V  P     + Q Q V+    A F+  +
Sbjct: 156  LKITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQC-I 214

Query: 1131 TKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----K 1184
              G  +  V W  DG  I   N +++  D    +L I     +D G Y C V N     +
Sbjct: 215  VSGHPVHDVNWLHDGKPILRDNRVEILTD--PPRLIIKKVQKEDPGMYQCFVSNEWEQIQ 272

Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
             TA L + + S        E  L P  T +   V   +     TW      I D+ +F +
Sbjct: 273  STAELQLGDASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLV 332

Query: 1245 -----ISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREY 1297
                 I D     + I    E+D  EYTC   +A  K +   KV +   P  I +  +  
Sbjct: 333  GQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLP-YIREMPKIT 391

Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT-DAG 1356
             I  GSD+ +      +P     W  + + +   +  +      + +L I++++   DAG
Sbjct: 392  GIS-GSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAY---NNGTLIIEQLQRLEDAG 447

Query: 1357 IYKLRLENN---CGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTI 1412
             Y    +N        +VE+ V +  K  P     N+L     +   C       G+  +
Sbjct: 448  TYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISC---QILEGDLPV 504

Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             +      E +    I   N    +    +      +    ++ N   I+     TE + 
Sbjct: 505  SFR----WERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFT 560

Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532
            V     +    + +P K+ + +   D+ L C   G P P +TW    K +      Y++ 
Sbjct: 561  VPLTVNVPPKWILEP-KDSSAQAGADVLLHCQSSGYPTPTITWK---KAIGPTPGEYKDF 616

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPVITIS---NEDIKQKH- 1584
                           +K I+    G    E + +   G+ +   + ++   +   K K  
Sbjct: 617  LYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQI 676

Query: 1585 --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI---RIKELKRSH 1639
                G +  V   ++G  P +  W     +   D+  +     +  V+    + EL  SH
Sbjct: 677  SVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736

Query: 1640 SSK-----YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694
            + +     Y  +ASN  G   + + L V + P +P+   I  + SR S+ + W  P   G
Sbjct: 737  TYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSR-SLQLTWSQPFA-G 794

Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVD-RDVETYC-IQKLNENCEYMFRVIAQNPVGFSEA 1752
               + +Y I  ++  ++ W     +     +T   IQ+L     Y  R+ A+N +G SE 
Sbjct: 795  NSPIEEYHIY-YKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEF 853

Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI-----IDYKVEIK 1807
              SE + + T  +VPS            +  +++TW   E++  + I     + Y++ + 
Sbjct: 854  --SEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLT 911

Query: 1808 QEGKKWKXXXXXXXXXARIQ----------KLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857
             E K+             ++           L+  T Y   + A    G+  P       
Sbjct: 912  PEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGSGPPSKEIAVQ 971

Query: 1858 TIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKI 1915
            T+     +PP  P+  V+    S S+ + W+ P+ +G    I  Y + + +V     T  
Sbjct: 972  TMEDVPSSPPESPQCDVLG---STSIYITWSPPDIDGQNGKIKGYKVFYISVDELYETDP 1028

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
              V  +     IEN+++       + A   VG  + T+    R   H  VPS P A   I
Sbjct: 1029 EVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCR--THEDVPSAPQAIKAI 1086

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGY 2001
                S I++ SW  P+   G  + GY
Sbjct: 1087 PASSSKIII-SWLPPDLPNG-DITGY 1110



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 123/586 (20%), Positives = 222/586 (37%), Gaps = 59/586 (10%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P T   +P+ Q VD   D   +C +   P  D+ WL  G+ I+ D  + +  +       
Sbjct: 191  PLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPR---- 246

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I  V+K   G Y    V+ E E  +    +++ G+   P+++       ++ G +V
Sbjct: 247  --LIIKKVQKEDPGMYQCF-VSNEWE-QIQSTAELQLGDAS-PELLYWFSEQTLQPGPTV 301

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-------DTHSITILKPKKVKDEGVYTL 805
             L     GNP P  TW  +  P+        G       D  S   +   K +D G YT 
Sbjct: 302  SLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTC 361

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A+N+ G    SA + +         P  +I    +IT      + +   V   P+  I 
Sbjct: 362  TAQNAIGKVSHSAKVNI------YGLP--YIREMPKITGISGSDLIVKCPVAGYPIDKIH 413

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W R+ + + P     + ++  N  L+I  +    D+G Y C+A N   ++S    V I V
Sbjct: 414  WERDGQTL-PINRRQRAYN--NGTLIIEQLQRLEDAGTYTCMAQNKQKQTSR-RNVEIQV 469

Query: 926  EKVTFVKHLQ-KSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGMDHREIIQEGRX 981
                 +  +Q  +    EG    + CQ       VS +W  N K + G  +    +    
Sbjct: 470  LVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEY 529

Query: 982  XXXXXXXXXXXD-VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILE 1037
                       D  G   CI  +   +    V  T+   P++I + +D   +     +L 
Sbjct: 530  SASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLH 589

Query: 1038 VEINS-ETADVVWERDGEIIKPKKNKY-DFEKRGHIR-----KLYIRNTSVHDEGEYSCI 1090
             + +   T  + W++    I P   +Y DF     ++      ++ +  S   +G + C 
Sbjct: 590  CQSSGYPTPTITWKK---AIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCE 646

Query: 1091 LRDE--SCTAEVTV--VELPPEIITRLQNQKVNKGNKATFEIELT---------KGDALV 1137
             ++   S  ++V    V +P    T+ +   V KG +   +  +          K  A  
Sbjct: 647  AKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQ 706

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
            ++  +  + +++   Q+  DG   +L I      D G Y C+  N+
Sbjct: 707  QYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNA 752



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 190/962 (19%), Positives = 353/962 (36%), Gaps = 82/962 (8%)

Query: 1138 RWFKDGSE----IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE- 1192
            RWFK+ +E    +Q S  I +   G    LKI    L+D+G+Y C V N+     + V  
Sbjct: 130  RWFKEENEQLLPLQLSERITIVSAGL---LKITKARLEDSGKYLCWVNNTAGEETIQVSL 186

Query: 1193 EPSINFTLRL-PEFILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVK 1249
              +   T  L P+   V  + DA     +    + DV W +  K ++ D  +  +++D  
Sbjct: 187  TVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDN-RVEILTDPP 245

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
            +  LII+K  ++D   Y C + +   +  +  ++++ +  P+++ +  E  ++ G  V+L
Sbjct: 246  R--LIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTVSL 303

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRL 1362
                   P P   W ++   I               D   + + I  V+  D G Y    
Sbjct: 304  KCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTA 363

Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQE 1421
            +N  G       V I   P     P I  I  S + + C   P        I++  + Q 
Sbjct: 364  QNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKC---PVAGYPIDKIHWERDGQT 420

Query: 1422 IDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480
            +       +  N T     +Q L+   +Y   A         +  + T    V  E ++ 
Sbjct: 421  LPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMA--------QNKQKQTSRRNV--EIQVL 470

Query: 1481 SPTVEKPLKNITTEPNEDIE--LTC-IFGGVPQPKVTWYRDGKKL-----KTAKATYENR 1532
             P    P++ +T    E +   ++C I  G       W R+GK L     +  +   E  
Sbjct: 471  VPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYS 530

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                           Y CIA N  G    +  + +   P   +  +D     + G + L+
Sbjct: 531  ASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKD--SSAQAGADVLL 588

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKE---YNITTKE-KTSVIRIKELKRSHSSKYTIEAS 1648
                 G P P + W K       + +   Y  T +      I  K++ +     +  EA 
Sbjct: 589  HCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAK 648

Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEWKPPLDDGGLELTKYAIEKHE 1707
            N  G+   +V     + P+  +       +++ + V ++     D+      K    +  
Sbjct: 649  NNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQQY 708

Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV---IAQNPVGFSEALESEPIVIKTAL 1764
             D +   +    D+ ++   + +L  +  Y       I Q    F +   S  ++++   
Sbjct: 709  LDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVP 768

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA 1824
            + P             + S+ +TW      G SPI +Y +  KQ    W+         A
Sbjct: 769  EQPKNLRINSQ----QSRSLQLTW-SQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAGA 823

Query: 1825 R----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE-STS 1879
            +    IQ+L     Y  R+ A N++G S  ++   ++T  + +  PS P   V +E  +S
Sbjct: 824  QTVINIQQLRPAKAYHIRMSAENKLGAS-EFSEVVQVTTLEEV--PSGPPLAVRAEPKSS 880

Query: 1880 RSVTLKWTEPESNGGSPIT-NYII--------EFKTVKGKSWTKIVTVGGSVH---EHCI 1927
              + + W  PE +  + I   Y +        E K V         TV    H   E  +
Sbjct: 881  TEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVL 940

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
             N+ +  +    + A  + G   P  S+ + ++    VPS P    +  ++GS  +  +W
Sbjct: 941  ANLNKFTQYHVIVQAYTSQGSGPP--SKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITW 998

Query: 1988 GTPEWDG-GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
              P+ DG    + GY +    V +    +   V        I +L +   Y + + A  +
Sbjct: 999  SPPDIDGQNGKIKGYKVFYISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTK 1058

Query: 2047 IG 2048
            +G
Sbjct: 1059 VG 1060



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 106/431 (24%), Positives = 171/431 (39%), Gaps = 52/431 (12%)

Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
           QF+C V G+P   + W      I      ++  D      L+I++V  ED G + C   N
Sbjct: 210 QFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPR---LIIKKVQKEDPGMYQCFVSN 266

Query: 588 AAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDE 647
                 ST EL     L D   E+                +  G  PT S K     V  
Sbjct: 267 EWEQIQSTAEL----QLGDASPELLYWFSEQT--------LQPG--PTVSLK----CVAT 308

Query: 648 GSDI-LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
           G+ +      L   P PD +    G+         V I  D+    S + I+NVK+   G
Sbjct: 309 GNPLPQFTWSLDGFPIPDSSRFLVGQ--------YVTIHDDV---ISHVNISNVKEEDGG 357

Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766
            YT  A N  G+ S       K      P + E  K   +  G  +I+   V G P   I
Sbjct: 358 EYTCTAQNAIGKVS----HSAKVNIYGLPYIREMPKITGI-SGSDLIVKCPVAGYPIDKI 412

Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            W ++ + +     +   +  ++ I + ++++D G YT  A+N +   +TS         
Sbjct: 413 HWERDGQTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQ--KQTS-----RRNV 465

Query: 827 EENAEPPLFINRFQEIT--VKEKGTIKLVARVTRNPVP-SITWYRNNE-IISPSETITQN 882
           E     P  I   Q +T  ++E     +  ++    +P S  W RN + +I     + + 
Sbjct: 466 EIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRR 525

Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
            D  +  LVI ++ S+  SG+Y C+ASN AG       +T++V     ++   K    + 
Sbjct: 526 LDEYSASLVIEHISSD-HSGNYTCIASNVAGTERFTVPLTVNVPPKWILE--PKDSSAQA 582

Query: 943 GKTVILECQTS 953
           G  V+L CQ+S
Sbjct: 583 GADVLLHCQSS 593



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 10/196 (5%)

Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914
            D+I     +  P +  N  V  + + S+ L+W +  S+GGSPI  Y+I +K   G  W +
Sbjct: 1255 DEIVYNIVVKVPPEAPNLTVINAYTDSLLLEWMD-NSHGGSPILGYVINYKRDNG-DWEE 1312

Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974
            +  V      H + N+         I+A N +G  LP +     +    T  +PP  P  
Sbjct: 1313 L-QVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCD-----IVNSYTKGNPPVQPKH 1366

Query: 1975 IRMVGSNIV-MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK-VDVNTLKFNIRDLS 2032
             +M+ +N   +T W     DGG  +L + I  R   ++ W  V   +      + + DL 
Sbjct: 1367 SQMITNNSTSVTCWLDSWGDGGCGILYFMIESRVYGRSSWAVVSNHIPPTERIYTVSDLV 1426

Query: 2033 ENHTYMIRIYARNEIG 2048
                Y +++ A N  G
Sbjct: 1427 PGTKYQLKVTAHNNAG 1442



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 83/382 (21%), Positives = 140/382 (36%), Gaps = 16/382 (4%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            D PS P     +   SS I I W  P+   G+ T   + +   E    E    + +    
Sbjct: 1075 DVPSAPQAIKAIPASSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGPFV 1134

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497
               + ++T  S  ++ +      + +  E T+   V    K+ +  V    + I T   E
Sbjct: 1135 EMHETVRTQESATYQFWLTASTKMGEG-EKTQVVTVPPNNKVPARIVSFS-QRIVTPWKE 1192

Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
             +EL C   G P P   W +DG  ++T A+ T                   Y C   N  
Sbjct: 1193 HLELPCRKVGAPAPVTIWRQDGHNMETSARKTIAKNGTLYMKECQASDAGNYTCSVENTW 1252

Query: 1557 G--EVETSCVVGI-QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            G  E+  + VV +  + P +T+ N        +  EW+  +   G  P  ++ Y    K 
Sbjct: 1253 GKDEIVYNIVVKVPPEAPNLTVIN---AYTDSLLLEWMDNS--HGGSP--ILGYVINYKR 1305

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            +N     +    KT+   +  L      +  I A N  GT      +  Y K + P  P 
Sbjct: 1306 DNGDWEELQVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGNPPVQPK 1365

Query: 1674 IMREISRESVTIE-WKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKL 1731
              + I+  S ++  W     DGG  +  + IE      + W  V++ +      Y +  L
Sbjct: 1366 HSQMITNNSTSVTCWLDSWGDGGCGILYFMIESRVYGRSSWAVVSNHIPPTERIYTVSDL 1425

Query: 1732 NENCEYMFRVIAQNPVGFSEAL 1753
                +Y  +V A N  G + A+
Sbjct: 1426 VPGTKYQLKVTAHNNAGSTTAI 1447



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 7/168 (4%)

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIY 1840
            +S+ + W  +  +GGSPI+ Y +  K++   W+         + +   L   T YQ  I 
Sbjct: 1280 DSLLLEWMDNS-HGGSPILGYVINYKRDNGDWEELQVDSKTTSHLLTNLWCGTRYQLYIT 1338

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N+IGT LP    +  T G    PP QP++  +  + S SVT  W +   +GG  I  +
Sbjct: 1339 AYNKIGTGLPCDIVNSYTKG---NPPVQPKHSQMITNNSTSVTC-WLDSWGDGGCGILYF 1394

Query: 1901 IIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
            +IE +     SW  +   +  +   + + ++    +   +++A N  G
Sbjct: 1395 MIESRVYGRSSWAVVSNHIPPTERIYTVSDLVPGTKYQLKVTAHNNAG 1442



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 104/465 (22%), Positives = 172/465 (36%), Gaps = 44/465 (9%)

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV--I 1605
            Y C A N  G+ E S  + +Q+ P     N  I  +     +   +    G  P E   I
Sbjct: 745  YICQASNAFGQDEMSIQLIVQEVPEQP-KNLRINSQQSRSLQLTWSQPFAGNSPIEEYHI 803

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            +YK  + +  + E+ +T     +VI I++L+ + +    + A N  G S     ++V   
Sbjct: 804  YYKQISDIWQNAEH-LTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTL 862

Query: 1666 PSKPEGPVIMREISRESVT---IEWKPPLDD--GGLELTKYA---------IEKHEPDNN 1711
               P GP +      +S T   + W  P  D   G+ L  Y           ++  P   
Sbjct: 863  EEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQG 922

Query: 1712 RWIKVADVDRDV--ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
               K  +V      ET  +  LN+  +Y   VI Q          S+ I ++T  DVPS 
Sbjct: 923  FSFKTVEVRSHFGGETV-LANLNKFTQY--HVIVQAYTSQGSGPPSKEIAVQTMEDVPSS 979

Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKV---EIKQEGKKWKXXXXXXXXXAR 1825
                     + + S+YITW P + +G    I  YKV    + +  +              
Sbjct: 980  PPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFYISVDELYETDPEVVKSTNQYVT 1039

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            I+ L   T Y   + A  ++G  +  T        + +  PS P+      ++S  + + 
Sbjct: 1040 IENLRKYTNYTVWVLAYTKVGDGMK-TKPFYCRTHEDV--PSAPQAIKAIPASSSKIIIS 1096

Query: 1886 WTEPESNGGSPITNYIIEFKTVKG--KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
            W  P+   G  IT Y      ++G  +  T    +G  V  H     +E     F ++A 
Sbjct: 1097 WLPPDLPNGD-ITGYTFYMSMLEGGREEGTHKRLLGPFVEMHETVRTQESATYQFWLTAS 1155

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG-SNIVMTSW 1987
              +G            EK   V  PP   +  R+V  S  ++T W
Sbjct: 1156 TKMGEG----------EKTQVVTVPPNNKVPARIVSFSQRIVTPW 1190



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 55/247 (22%), Positives = 92/247 (37%), Gaps = 19/247 (7%)

Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654
           +  L++E   SDH    T               +   +PP +  +PK      G+D+LL 
Sbjct: 530 SASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLH 589

Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGTYTVVAV 713
           C+    P P I W  K     P E      E  + ++ +  +    + K  +G +   A 
Sbjct: 590 CQSSGYPTPTITWK-KAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAK 648

Query: 714 NREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW---C 769
           N  G   S  I LK+      P       K + V +G+ V +   V G+      W    
Sbjct: 649 NNIGSGVSKVIFLKVNV----PAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQA 704

Query: 770 KNNKPVKALPTK--------SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
                 ++L ++         DG    + I    + +D G+Y  +A N+ G  E S  + 
Sbjct: 705 TQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYR-QDTGIYICQASNAFGQDEMSIQLI 763

Query: 822 VEEPTEE 828
           V+E  E+
Sbjct: 764 VQEVPEQ 770



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 42/166 (25%), Positives = 79/166 (47%), Gaps = 14/166 (8%)

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
            +K+ +L +K+ + +DAG Y   +EN  G  ++  N+ +     PP  PN+  I++ + ++
Sbjct: 1226 AKNGTLYMKECQASDAGNYTCSVENTWGKDEIVYNIVV---KVPPEAPNLTVINAYTDSL 1282

Query: 1400 CWDEPENT-GNSTIIYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVN 1457
              +  +N+ G S I+ YV+ Y+  D  +W  ++  +KT +  + NL   + Y+    A N
Sbjct: 1283 LLEWMDNSHGGSPILGYVINYKR-DNGDWEELQVDSKTTSHLLTNLWCGTRYQLYITAYN 1341

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503
            ++      +    Y     TK   P   K  + IT   N    +TC
Sbjct: 1342 KIGTGLPCDIVNSY-----TKGNPPVQPKHSQMIT---NNSTSVTC 1379



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 86/414 (20%), Positives = 159/414 (38%), Gaps = 28/414 (6%)

Query: 1648 SNTAGTSSVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPP-LDDGGLELTKYAIEK 1705
            S  +G  S E+ ++   D PS P        +   S+ I W PP +D    ++  Y +  
Sbjct: 958  SQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFY 1017

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765
               D         V    +   I+ L +   Y   V+A   VG  + ++++P   +T  D
Sbjct: 1018 ISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVG--DGMKTKPFYCRTHED 1075

Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVEIKQEGKK---WKXXXXXXX 1821
            VPS            +  + I+W P +  NG      + + + + G++    K       
Sbjct: 1076 VPSAPQAIKAIPA-SSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGPFV 1134

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                  +   + TYQF + A  ++G          +T+      P++  +F     T   
Sbjct: 1135 EMHETVRTQESATYQFWLTASTKMGEG---EKTQVVTVPPNNKVPARIVSFSQRIVTPWK 1191

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
              L+    +    +P+T +  +   ++  S  K +   G+++   ++  +  D   +  S
Sbjct: 1192 EHLELPCRKVGAPAPVTIWRQDGHNME-TSARKTIAKNGTLY---MKECQASDAGNYTCS 1247

Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000
             ENT G           +  +  V  PP AP L +    ++ ++  W      GG+P+LG
Sbjct: 1248 VENTWGKD--------EIVYNIVVKVPPEAPNLTVINAYTDSLLLEW-MDNSHGGSPILG 1298

Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054
            Y I  +      W E+ +VD  T    + +L     Y + I A N+IG   P +
Sbjct: 1299 YVINYKR-DNGDWEEL-QVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCD 1350



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF----QMYYDDDNVATLVIREVFPEDAG 579
           G TV  +C   G P PQ TW      I  S  F     +   DD ++ + I  V  ED G
Sbjct: 298 GPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGG 357

Query: 580 TFTCVAKNAAGFASSTTEL 598
            +TC A+NA G  S + ++
Sbjct: 358 EYTCTAQNAIGKVSHSAKV 376



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 6/72 (8%)

Query: 518 PKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP- 575
           PK T   GS +  +C V GYP  +I W R    +  ++  + Y    N  TL+I ++   
Sbjct: 388 PKITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAY----NNGTLIIEQLQRL 443

Query: 576 EDAGTFTCVAKN 587
           EDAGT+TC+A+N
Sbjct: 444 EDAGTYTCMAQN 455



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 2/98 (2%)

Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLV 569
           I VEK   +H          C  +G+P P   WF++    + P Q         +   L 
Sbjct: 99  INVEKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFKEENEQLLPLQ-LSERITIVSAGLLK 157

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
           I +   ED+G + C   N AG  +    L V APL+ H
Sbjct: 158 ITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAH 195



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 3/130 (2%)

Query: 700  VKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
            V+  +  TY   + A  + GE     V+ +    K P +++   + ++    E + L  +
Sbjct: 1140 VRTQESATYQFWLTASTKMGEGEKTQVVTVPPNNKVPARIVSFSQRIVTPWKEHLELPCR 1199

Query: 758  VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817
             VG P P   W ++   ++    K+     ++  +K  +  D G YT   EN+ G  E  
Sbjct: 1200 KVGAPAPVTIWRQDGHNMETSARKTIAKNGTL-YMKECQASDAGNYTCSVENTWGKDEIV 1258

Query: 818  AVITVEEPTE 827
              I V+ P E
Sbjct: 1259 YNIVVKVPPE 1268



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 11/152 (7%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV- 565
           ++ P ++ + +      G+ V   CQ  GYP P ITW  + AI     +++ +  +  V 
Sbjct: 566 NVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITW--KKAIGPTPGEYKDFLYEPTVQ 623

Query: 566 ----ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
                T+  +++  E  G F C AKN  G   S   + ++  +  H    T         
Sbjct: 624 LFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKV-IFLKVNVPAHFQTKTKQISVAKGK 682

Query: 622 XXXXADILEGIPP-TFSKKPKA--QYVDEGSD 650
                  ++G  P  F  K +A  QY+DE  D
Sbjct: 683 QVHVQCNVQGDNPIDFKWKIQATQQYLDESLD 714



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 1/82 (1%)

Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           +G      CQ+ EG       W R    +  + +      D+  A+LVI  +  + +G +
Sbjct: 487 EGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNY 546

Query: 582 TCVAKNAAGFASSTTELIVEAP 603
           TC+A N AG    T  L V  P
Sbjct: 547 TCIASNVAGTERFTVPLTVNVP 568


>UniRef50_Q696W0 Cluster: Striated muscle preferentially expressed
            protein kinase; n=7; Danio rerio|Rep: Striated muscle
            preferentially expressed protein kinase - Danio rerio
            (Zebrafish) (Brachydanio rerio)
          Length = 2995

 Score =  100 bits (239), Expect = 5e-19
 Identities = 85/390 (21%), Positives = 156/390 (40%), Gaps = 17/390 (4%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P  +    +  +  G +  L       P P   W  N K I+     K +      SL I
Sbjct: 840  PDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVI 899

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSPPGKPNILE-IDSSSINICWDEPE 1405
            + V +  +G+YK  + N  G A    ++ + +  P PP  P ++E +    I + W +P+
Sbjct: 900  QSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPK 959

Query: 1406 NTGNS---TIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
            N   S     + YVV+ Q + +T+W ++  ++T T  ++ +L     Y FR  +     +
Sbjct: 960  NLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTL 1019

Query: 1462 SDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
            S  S+ T+  +++   +   ++P +      +    N+ + +T     V Q   TW R G
Sbjct: 1020 SKPSQPTDLVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTITITINHV-QATCTWKRRG 1078

Query: 1520 ----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI--AFNDHGEVETSCVVGIQQKPVI 1573
                 KL   + T  +                 + I  A N +G    +  + I   P+ 
Sbjct: 1079 VVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIF 1138

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633
                ED+     VG+      V++G P P+++WYK+G  L           ++   + + 
Sbjct: 1139 ETIMEDLDVC--VGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVL 1196

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
              +      YT  A N AG+ S +  L V+
Sbjct: 1197 NAQPEDVGVYTCTAKNLAGSVSCKAELTVH 1226



 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 71/263 (26%), Positives = 117/263 (44%), Gaps = 11/263 (4%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           S  P+F  KL      +G + QF+C+V G P P++TW      +  S +  +  + +   
Sbjct: 711 SKEPLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHI-LNVNGHH 769

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623
           +L+I  V  E  G +T +A+N  G A+S+ EL V+ P   +S H S +            
Sbjct: 770 SLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEV 829

Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683
              ++     P F K      V EG + +L+CR+  +P P I W   G++I    +  + 
Sbjct: 830 PEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMT 889

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743
              D+H     L I +V     G Y  V  N+ G+A+    L +     EPP     ++S
Sbjct: 890 QYRDVHS----LVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIES 945

Query: 744 MIVRQGESVILSAQVVGNPRPTI 766
           +    G  ++LS +   N  P+I
Sbjct: 946 V---TGRMILLSWKKPKNLDPSI 965



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 88/311 (28%), Positives = 130/311 (41%), Gaps = 38/311 (12%)

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           V  G   LLEC +      D+ WL  G+ I P       ++ D H  C +L   +  +  
Sbjct: 629 VKAGETALLECFIAGSQAVDVDWLANGKLIQP-ALFDCKMQFDGHR-CRLL-FKSAHEND 685

Query: 705 EGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
            G YT  ++  +E       +L I + E    + +E L+++   +G S     +V G P 
Sbjct: 686 SGCYTCKLSTAKEELICTANLLVIPSKEPLFTRKLEVLEAI---EGRSAQFDCKVSGCPP 742

Query: 764 PTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
           P +TW    KP+     +   +    HS+ I    K + EG+YT  A+N  G A +SA +
Sbjct: 743 PEVTWTHCEKPLVESDNIHILNVNGHHSLLITHVNK-ESEGLYTAIAQNVHGKAASSAEL 801

Query: 821 TVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKLVA 854
            V+EP                  EE   P         P FI    ++ V E     L  
Sbjct: 802 YVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKC 861

Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
           RVT  P P ITWY N + I  +         +   LVI +V  +  SG YKCV SN  GK
Sbjct: 862 RVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVIQSVCHD-HSGVYKCVISNKVGK 920

Query: 915 SSHGARVTIDV 925
           ++  A + + V
Sbjct: 921 AACYAHLYVAV 931



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 5/161 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G E ++   + G+P P++ WY NG K+E+  +  +T       + I+ +   HS  Y   
Sbjct: 854  GKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVIQSVCHDHSGVYKCV 913

Query: 1647 ASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702
             SN  G ++    L V    P  P+GP ++  ++   + + WK P + D  ++     Y 
Sbjct: 914  ISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPKNLDPSIDPASLMYV 973

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743
            +++    + +W  +A    D  +Y +  L++   Y FRV++
Sbjct: 974  VQQQVLGSTQWTTIASSLTDT-SYTVTSLSKGVCYSFRVLS 1013



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 82/343 (23%), Positives = 130/343 (37%), Gaps = 67/343 (19%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582
           G T   EC + G     + W     +I+P+  D +M +D      L+ +     D+G +T
Sbjct: 632 GETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHR-CRLLFKSAHENDSGCYT 690

Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
           C    A        ELI  A L                       ++    P F++K + 
Sbjct: 691 CKLSTAK------EELICTANLL----------------------VIPSKEPLFTRKLEV 722

Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
               EG     +C++   P P++ W    + +V  +NI +   +  H     L IT+V K
Sbjct: 723 LEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILNVNGHHS----LLITHVNK 778

Query: 703 FQEGTYTVVAVNREGEA--------------------------SLPIVLKIKTGEKEP-- 734
             EG YT +A N  G+A                          S+P   ++  GE E   
Sbjct: 779 ESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRT 838

Query: 735 -PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790
            P  I+PL  + V +G+  +L  +V G P P ITW  N K +++   +      D HS+ 
Sbjct: 839 MPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSL- 897

Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
           +++       GVY     N  G A   A + V     E  + P
Sbjct: 898 VIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGP 940



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 17/234 (7%)

Query: 712 AVNREGEASLPIVLKIKTGEKEPPQ----VIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           A+   G   L  ++K  T  + P +    +  P++ + V+ GE+ +L   + G+    + 
Sbjct: 591 ALGTAGSELLQCIIKENTVARAPAESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVD 650

Query: 768 WCKNNKPVK--ALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENS-EGIAETSAVITVE 823
           W  N K ++      K   D H   +L K     D G YT K   + E +  T+ ++ + 
Sbjct: 651 WLANGKLIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTANLLVI- 709

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQN 882
            P++E    PLF  + + +   E  + +   +V+  P P +TW    + +  S+ I   N
Sbjct: 710 -PSKE----PLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILN 764

Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            +G +  L+IT+V+ E   G Y  +A N  GK++  A + +   +     H+ +
Sbjct: 765 VNGHH-SLLITHVNKE-SEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSR 816



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 507  SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
            ++ PIF   +       G T  F   V+G P P I W++   ++  S      YDD    
Sbjct: 1133 AVPPIFETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRE-C 1191

Query: 567  TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +LV+    PED G +TC AKN AG  S   EL V
Sbjct: 1192 SLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTV 1225



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 53/214 (24%), Positives = 96/214 (44%), Gaps = 11/214 (5%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK--HTKPSIDSKS 1342
            +FPP      +++ +  G+ VTL       P+P   W+ + K +K C   + +   D + 
Sbjct: 2321 DFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQ 2380

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402
              L I  +   DAGIY+    NN         +T+   P+ PG P I +I ++++ + W 
Sbjct: 2381 L-LMIMNISKKDAGIYECVATNNLASVTTSCILTLACIPNCPGTPEIRQIYNNTVLVQW- 2438

Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
            +P +T       Y +E +     +W++    +T    +   L + S+ RFR   VN+   
Sbjct: 2439 KPSDT--KVPCTYTIEKKFDGDDKWLTEATGVTDCFFNSSELPSGSTIRFRVACVNKAGQ 2496

Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495
            S  S  ++   +  +TK+ +P   +P K  T  P
Sbjct: 2497 SPYSNESDGVSI--DTKV-TPQ-HQPAKMKTHSP 2526



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 62/252 (24%), Positives = 104/252 (41%), Gaps = 25/252 (9%)

Query: 723  IVLKIKTGE--KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-----NKPV 775
            +V  +  GE  ++ P +I+    +   + + V ++   + + + T TW +      NK  
Sbjct: 1028 LVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTITI-TINHVQATCTWKRRGVVLVNKLG 1086

Query: 776  KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835
                T  D D H++ I K K   D G     A N  G    +  + +       A PP+F
Sbjct: 1087 ALEMTTPDDDQHALHIAKVKST-DVGQLIFMANNQYGSDLGTLQLVI-------AVPPIF 1138

Query: 836  INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895
                +++ V    T      V   P P I WY++  +++ S  +T  +D     LV+ N 
Sbjct: 1139 ETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVLNA 1198

Query: 896  DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955
              E D G Y C A N AG  S  A +T+        +++++  E  E +  IL       
Sbjct: 1199 QPE-DVGVYTCTAKNLAGSVSCKAELTVHT-----AQNVEEEEEQMEDEATILR---RMR 1249

Query: 956  VSTKWYHNKKEI 967
            + T +Y   KEI
Sbjct: 1250 MLTDYYDIHKEI 1261



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 54/210 (25%), Positives = 98/210 (46%), Gaps = 13/210 (6%)

Query: 996  VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054
            +++CI+K  E +      E++    R +QD +VK  + A+LE  I  S+  DV W  +G+
Sbjct: 599  LLQCIIK--ENTVARAPAESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVDWLANGK 656

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDE-SCTAEVTVVELPPEII 1110
            +I+P       +  GH  +L  ++   +D G Y+C L   ++E  CTA + V+     + 
Sbjct: 657  LIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTANLLVIPSKEPLF 716

Query: 1111 TR-LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168
            TR L+  +  +G  A F+ +++      V W      +  S++I +        L I   
Sbjct: 717  TRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILNVNGHHSLLITHV 776

Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEP 1194
            + +  G Y+       G +  +A L V+EP
Sbjct: 777  NKESEGLYTAIAQNVHGKAASSAELYVQEP 806



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 3/119 (2%)

Query: 490 EKIDKLPVF-EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547
           EK+  +P   E P  E E+   P F++ L      +G     +C+V G P P+ITW+   
Sbjct: 818 EKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNG 877

Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
             I+ + D +M    D V +LVI+ V  + +G + CV  N  G A+    L V   L +
Sbjct: 878 KKIESTNDRKMTQYRD-VHSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPE 935



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 491  KIDKLPVFEK-PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
            K D+ P   + P + ++   P+F   L+     +G+ V   C   G P P+I W +    
Sbjct: 2304 KRDRTPSNSRAPATPKEDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKP 2363

Query: 550  IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +K      +    D    L+I  +  +DAG + CVA N    AS TT  I+
Sbjct: 2364 LKLCDGMNLEACPDGRQLLMIMNISKKDAGIYECVATN--NLASVTTSCIL 2412



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 5/96 (5%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           PP  +  LK   V  G  V L   V GNPRPT+ W  N+ P+       D + +    ++
Sbjct: 27  PPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDDPLVI-----DHEDYDGLWIR 81

Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
             +  D G+YT  A N  G A TSAV+ V +  E++
Sbjct: 82  DCQQADGGLYTCVAVNHLGEARTSAVLAVLDLEEDS 117



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTH 787
            E  PP     LK  ++ +G  V LS    G+P P I W K+ KP+K    +  ++  D  
Sbjct: 2320 EDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGR 2379

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
             + ++     KD G+Y   A N+     TS ++T+
Sbjct: 2380 QLLMIMNISKKDAGIYECVATNNLASVTTSCILTL 2414



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 43/178 (24%), Positives = 78/178 (43%), Gaps = 7/178 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTI 1645
            G+   ++ +  G P P+++W K+   L+     N+    +   ++ I  + +  +  Y  
Sbjct: 2338 GNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQLLMIMNISKKDAGIYEC 2397

Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705
             A+N   + +    L +   P+ P  P I R+I   +V ++WKP   D  +  T Y IEK
Sbjct: 2398 VATNNLASVTTSCILTLACIPNCPGTPEI-RQIYNNTVLVQWKP--SDTKVPCT-YTIEK 2453

Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT 1762
                +++W+  A    D   +   +L       FRV   N  G S  + ES+ + I T
Sbjct: 2454 KFDGDDKWLTEATGVTDC-FFNSSELPSGSTIRFRVACVNKAGQSPYSNESDGVSIDT 2510



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 5/89 (5%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536
            P     LK+        + L+C+  G P+PK+ W +D K LK       +A  + R    
Sbjct: 2324 PVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQLLM 2383

Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565
                       Y+C+A N+   V TSC++
Sbjct: 2384 IMNISKKDAGIYECVATNNLASVTTSCIL 2412



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 37/151 (24%), Positives = 60/151 (39%), Gaps = 5/151 (3%)

Query: 830 AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQNFDGEN 887
           AE  L I R  Q++ VK   T  L   +  +    + W  N ++I P+       FDG  
Sbjct: 614 AESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHR 673

Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
             L+  +   E DSG Y C  S +  +    A + +   K        +  E  EG++  
Sbjct: 674 CRLLFKSAH-ENDSGCYTCKLSTAKEELICTANLLVIPSKEPLFTRKLEVLEAIEGRSAQ 732

Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREII 976
            +C+ S        W H +K +   D+  I+
Sbjct: 733 FDCKVSGCPPPEVTWTHCEKPLVESDNIHIL 763



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 8/91 (8%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P+F+ KL+      G  V+    V G PRP + W+          D  +  D ++   L 
Sbjct: 28  PVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYH--------NDDPLVIDHEDYDGLW 79

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           IR+    D G +TCVA N  G A ++  L V
Sbjct: 80  IRDCQQADGGLYTCVAVNHLGEARTSAVLAV 110



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 9/99 (9%)

Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
           A PP+F+ + +   V     ++L   V  NP P++ WY N++   P     +++DG    
Sbjct: 25  AAPPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDD---PLVIDHEDYDG---- 77

Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEK 927
           L I +   + D G Y CVA N  G++   A + + D+E+
Sbjct: 78  LWIRDC-QQADGGLYTCVAVNHLGEARTSAVLAVLDLEE 115



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 6/114 (5%)

Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP 1058
            I ++ E     V + T+P+FI+ L D EV E   A+L+  +       + W  +G+ I+ 
Sbjct: 823  IPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIES 882

Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108
              ++   + R  +  L I++      G Y C++ ++    +C A + V    PE
Sbjct: 883  TNDRKMTQYR-DVHSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPE 935



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 3/98 (3%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E  PP F    K   + EG+ + L C     PEP I WL   + +   + +++    D  
Sbjct: 2320 EDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGR 2379

Query: 690  MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
                +L I N+ K   G Y  VA N     +   +L +
Sbjct: 2380 ---QLLMIMNISKKDAGIYECVATNNLASVTTSCILTL 2414



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 40/196 (20%), Positives = 78/196 (39%), Gaps = 13/196 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE-IQFSNHIQLTI-DGKKQKLK 1164
            P+I+  ++NQ V      T  I +    A   W + G   +     +++T  D  +  L 
Sbjct: 1048 PDIVYAVENQPV------TITITINHVQATCTWKRRGVVLVNKLGALEMTTPDDDQHALH 1101

Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220
            I      D G+     + + G+   T  L +  P I  T+ + +  +    T  +  V  
Sbjct: 1102 IAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIFETI-MEDLDVCVGETCHFAVVVD 1160

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
                 D+ WYK   ++ ++   T + D ++ +L++     +D   YTC   +   +   K
Sbjct: 1161 GKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVLNAQPEDVGVYTCTAKNLAGSVSCK 1220

Query: 1281 VEVVEFPPKIVDYERE 1296
             E+     + V+ E E
Sbjct: 1221 AELTVHTAQNVEEEEE 1236



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 11/101 (10%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F +K K   V  G D+ L   +   P P + W    + +V D           H   
Sbjct: 27  PPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDDPLVID-----------HEDY 75

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733
             L I + ++   G YT VAVN  GEA    VL +   E++
Sbjct: 76  DGLWIRDCQQADGGLYTCVAVNHLGEARTSAVLAVLDLEED 116



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 9/143 (6%)

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIE 889
            PP+F    ++  + E   + L      +P P I W ++ + +   + +      DG  + 
Sbjct: 2323 PPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQL- 2381

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKVTFVKHLQKSYETEEGKTVIL 948
            L+I N+ S+ D+G Y+CVA+N+    +    +T+  +        +++ Y      TV++
Sbjct: 2382 LMIMNI-SKKDAGIYECVATNNLASVTTSCILTLACIPNCPGTPEIRQIY----NNTVLV 2436

Query: 949  ECQTSHTVSTKWYHNKKEISGMD 971
            + + S T     Y  +K+  G D
Sbjct: 2437 QWKPSDTKVPCTYTIEKKFDGDD 2459


>UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor
            tyrosine phosphatase type r2a; n=1; Nasonia
            vitripennis|Rep: PREDICTED: similar to receptor tyrosine
            phosphatase type r2a - Nasonia vitripennis
          Length = 2046

 Score =   99 bits (238), Expect = 7e-19
 Identities = 137/630 (21%), Positives = 238/630 (37%), Gaps = 36/630 (5%)

Query: 1436 TQTSIQNLKTN-SSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493
            T   I+ +++N  +  +   A N V D   A+ +   Y+V K  K      + P   +  
Sbjct: 98   TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVV- 156

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCI 1551
            E   + +L+C   G P P ++W R+   + T+   Y                    Y+C+
Sbjct: 157  EKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYECV 216

Query: 1552 AFNDHG-EVETSCVVGIQQKPVIT-ISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608
            A N  G E   S  + ++ + V+   S + D   +  +G+   +T V  G P P V W K
Sbjct: 217  ATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRK 276

Query: 1609 N-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
                 L  D +     K   +V+ +K +    S+ YT  A +  G  +    +KV   P 
Sbjct: 277  EPATDLTPDNQMPPIGK---NVLHLKNV--HESANYTCIAQSDLGVINTTTYVKVRSLPL 331

Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727
             PE  V + EI+  SV + W       G E   Y + +H+P +               Y 
Sbjct: 332  APEN-VQVSEITATSVKLTWSYK----GPESLAYYVIQHKPKHAHQAYAEISGITTMYYM 386

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787
            ++ L+   EY F VIA N +G      S P+V+ T    P           + + +  I 
Sbjct: 387  VRSLSPYTEYEFFVIAVNDIG--RGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTALIQ 444

Query: 1788 WFPSEKNGGSPIIDYKV----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
            W   E   G  +  YKV    +  Q    W+           I  L+ +  Y  R+ A  
Sbjct: 445  WDEPETPNGQ-VTGYKVYYTTDSGQPMSNWQFQTVDNNQLTTISDLTAHAIYTIRVQALT 503

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
             +G   P +S  +I   + +  PSQP      E     VTLKW +P  +  + ++  +  
Sbjct: 504  SVGPG-PLSSPVQIKTQQGV--PSQPEMLQAVEVGENKVTLKWNKPSISAENILSYELYW 560

Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963
              T   +   + + V      + + N+         ++A +  G    T    VR E++ 
Sbjct: 561  NDTYAQEKHHRKIPV---AENYTLTNLYPNTLYYVWLAARSQRGEGATTIPLPVRTEQY- 616

Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
             VP  P   +         ++  W  P  +     ++ Y +   +  ++   E   V +N
Sbjct: 617  -VPGAPPRNVTGLPTSPTSILVKWEPPPVERSNGRIVYYKLHYVENGRSD-SESSIVTLN 674

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
              +F + +L +   Y I + A   +G   P
Sbjct: 675  GTEFVLDELKKWTEYRIWVVAGTSVGDGPP 704



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 202/998 (20%), Positives = 367/998 (36%), Gaps = 90/998 (9%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF---SNHIQLTIDGKKQ 1161
            PP  I + Q+Q V  G  A+F    +      + W K+  +I     SN   +       
Sbjct: 39   PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGT 98

Query: 1162 KLKIYDCDLD-DAGEYSCEVGNS-----KCTAILTVEE-----PSINFTLRLPEFILVPA 1210
             L+I     + DA  Y C   N        TA LT+ E            + P   +V  
Sbjct: 99   LLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVEK 158

Query: 1211 NTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              +A L+       +  ++W + +  I+ +    ++  ++   L I     DDQ +Y CV
Sbjct: 159  GHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVV--LESGALQITDSDPDDQGKYECV 216

Query: 1270 LLDAKST-----TKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
              ++  T     T+L V++    P      +    +  G    L       P P  +W  
Sbjct: 217  ATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRK 276

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
                     +  P I      L +K V   ++  Y    +++ G  +    V +   P  
Sbjct: 277  EPATDLTPDNQMPPIGKN--VLHLKNVH--ESANYTCIAQSDLGVINTTTYVKVRSLPLA 332

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQTSIQN 1442
            P    + EI ++S+ + W      G  ++ YYV++++     + +  +  IT     +++
Sbjct: 333  PENVQVSEITATSVKLTW---SYKGPESLAYYVIQHKPKHAHQAYAEISGITTMYYMVRS 389

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP---TVEKPLKNITTEPNEDI 1499
            L   + Y F   AVN  DI     ++       ETK  S       +PL + T     D 
Sbjct: 390  LSPYTEYEFFVIAVN--DIGRGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTALIQWD- 446

Query: 1500 ELTCIFGGVPQPKVTWYRD-GKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557
            E     G V   KV +  D G+ +   +  T +N                 +  A    G
Sbjct: 447  EPETPNGQVTGYKVYYTTDSGQPMSNWQFQTVDNNQLTTISDLTAHAIYTIRVQALTSVG 506

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQ----KHKVGDEWLVTAV-IEGIPPPEVIW------ 1606
                S  V I+ +  +    E ++     ++KV  +W   ++  E I   E+ W      
Sbjct: 507  PGPLSSPVQIKTQQGVPSQPEMLQAVEVGENKVTLKWNKPSISAENILSYELYWNDTYAQ 566

Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
             K+  K+   + Y +T     ++  +    RS       +    A T  + V  + Y  P
Sbjct: 567  EKHHRKIPVAENYTLTNLYPNTLYYVWLAARS-------QRGEGATTIPLPVRTEQY-VP 618

Query: 1667 SKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVE 1724
              P   V     S  S+ ++W+ PP++     +  Y +  H  +N R    +  V  +  
Sbjct: 619  GAPPRNVTGLPTSPTSILVKWEPPPVERSNGRIVYYKL--HYVENGRSDSESSIVTLNGT 676

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + + +L +  EY   V+A   VG  +   S PI ++T  DVP           I+  ++
Sbjct: 677  EFVLDELKKWTEYRIWVVAGTSVG--DGPPSYPITVRTHEDVPG-DPQNVKATPINATAI 733

Query: 1785 YITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXXXARIQK--LSIN-------TT 1834
            Y+ W P +    + II  Y V +++  ++ K           +++  L +N       T 
Sbjct: 734  YVEWEPPKSKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLHVNISGLQPDTR 793

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESN 1892
            Y  ++ A    G           T G     PS+P   +  +S      + L WT P   
Sbjct: 794  YDVQVAALTRKGDGARSIPVSVKTPGGV---PSRPSLIIKTISREDPIEMQLDWTRPTQT 850

Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD-EIIFRISAENTVGVSLP 1951
             G  I  Y I +  +  ++  ++   G SVH + I++++E+  +  FR++ +N VG    
Sbjct: 851  YGQ-ILGYRIRYGII-NQTLKEVFLEGDSVHSYRIKDLEERGVDYEFRVAGKNEVGFG-- 906

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTK 2010
             + Q          P+ P   L       + V  +W  P+       ++ YN+     + 
Sbjct: 907  -QEQVRNWFSQEGAPTGPPTNLSFHFQTPDTVCVTWDPPQQKFRNGKIVSYNVQFHKKSD 965

Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
                EV + ++   +    +L EN  Y+  + A    G
Sbjct: 966  HT-SEVTR-NITKTRAVFTNLDENTEYVFHVKAYTSRG 1001



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 82/317 (25%), Positives = 126/317 (39%), Gaps = 34/317 (10%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQ-MYYDDDNVAT 567
           P F++K + +   +G    F C   G P PQI W +    I+  +Q  + M Y  +N   
Sbjct: 40  PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99

Query: 568 LVIREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
           L I  V    DA  + C+A+N  G A S T            + +T+             
Sbjct: 100 LRIEPVRSNRDAIAYECLAENGVGDAVSAT------------ASLTI----------YEV 137

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
           D L    P  ++ P  + V++G +  L C  +  P P I+W+     I       V +ES
Sbjct: 138 DKLPKGFPMITQAPTTKVVEKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLES 197

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                   L+IT+     +G Y  VA N  G E S    L +K     P    +P   + 
Sbjct: 198 ------GALQITDSDPDDQGKYECVATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVE 251

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
           V  GES  L+    G+P P + W K  +P   L   +        +L  K V +   YT 
Sbjct: 252 VTLGESTNLTCVAYGSPMPYVKWRK--EPATDLTPDNQMPPIGKNVLHLKNVHESANYTC 309

Query: 806 KAENSEGIAETSAVITV 822
            A++  G+  T+  + V
Sbjct: 310 IAQSDLGVINTTTYVKV 326



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 66/289 (22%), Positives = 118/289 (40%), Gaps = 19/289 (6%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F +KP++Q V  G      C     P P I W    ++I+   N S       +   
Sbjct: 39  PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIM-STNQSNRFMVYPYENG 97

Query: 693 SVLKITNVKKFQEG-TYTVVAVNREGEA-SLPIVLKIKTGEKEP---PQVIEPLKSMIVR 747
           ++L+I  V+  ++   Y  +A N  G+A S    L I   +K P   P + +   + +V 
Sbjct: 98  TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVE 157

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           +G +  LS   +G+P P I+W +N  P+     +          +      D+G Y   A
Sbjct: 158 KGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYECVA 217

Query: 808 ENSEGI---AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
            NS G      T   + +       +  P   +   E+T+ E   +  VA    +P+P +
Sbjct: 218 TNSVGTEYSKSTQLYVKIRRVLPHFSRQP---DPVVEVTLGESTNLTCVA--YGSPMPYV 272

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
            W +      P+  +T +     I   + ++ +  +S +Y C+A +  G
Sbjct: 273 KWRK-----EPATDLTPDNQMPPIGKNVLHLKNVHESANYTCIAQSDLG 316



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 92/420 (21%), Positives = 163/420 (38%), Gaps = 38/420 (9%)

Query: 1604 VIWYKNGNKLEN---DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEV 1658
            +++YK  + +EN   D E +I T   T  + + ELK+    +  + A  + G    S  +
Sbjct: 651  IVYYKL-HYVENGRSDSESSIVTLNGTEFV-LDELKKWTEYRIWVVAGTSVGDGPPSYPI 708

Query: 1659 TLKVY-DKPSKPEGPVIMREISRESVTIEWKPP--LDDGGLELTKYAIEKHEPDN----- 1710
            T++ + D P  P+  V    I+  ++ +EW+PP   +  G+ +  Y +   E        
Sbjct: 709  TVRTHEDVPGDPQN-VKATPINATAIYVEWEPPKSKERNGI-IRGYHVHVQEVSEETKNQ 766

Query: 1711 -NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769
             N  I+   ++ DV    I  L  +  Y  +V A    G  +   S P+ +KT   VPS 
Sbjct: 767  LNDPIRSISLEEDVLHVNISGLQPDTRYDVQVAALTRKG--DGARSIPVSVKTPGGVPSR 824

Query: 1770 -XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARI 1826
                       D   + + W    +  G  I+ Y++   I  +  K            RI
Sbjct: 825  PSLIIKTISREDPIEMQLDWTRPTQTYGQ-ILGYRIRYGIINQTLKEVFLEGDSVHSYRI 883

Query: 1827 QKL-SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            + L      Y+FR+  +NE+G       +      +   P   P N      T  +V + 
Sbjct: 884  KDLEERGVDYEFRVAGKNEVGFGQEQVRN---WFSQEGAPTGPPTNLSFHFQTPDTVCVT 940

Query: 1886 WTEPESN-GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
            W  P+       I +Y ++F   K    T  VT   +       N+ E  E +F + A  
Sbjct: 941  WDPPQQKFRNGKIVSYNVQFH--KKSDHTSEVTRNITKTRAVFTNLDENTEYVFHVKAYT 998

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG-SNIVMTSWGTPEWDGGAPLLGYNI 2003
            + G    +E  ++  +K         AP+ ++ +  S+     W  P  + G  ++GY I
Sbjct: 999  SRGGGPYSEKITILTDKDI-----GRAPMSVKAIATSDSSAEVWWEPVPNRG-KIIGYEI 1052



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 111/487 (22%), Positives = 182/487 (37%), Gaps = 65/487 (13%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKP--KKNK---YDFEKRGH 1070
            P FI+K Q   VK   +A      + S    + W ++ + I    + N+   Y +E    
Sbjct: 40   PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99

Query: 1071 IRKLYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVE---LPP--EIITRLQNQKV-N 1119
            +R   +R+    D   Y C+  +      S TA +T+ E   LP    +IT+    KV  
Sbjct: 100  LRIEPVRSN--RDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVE 157

Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            KG+ A            ++ W ++   I  SN   + ++     L+I D D DD G+Y C
Sbjct: 158  KGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGA--LQITDSDPDDQGKYEC 215

Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYK------ 1231
               NS  T      +  +     LP F   P   D  + V + + T L    Y       
Sbjct: 216  VATNSVGTEYSKSTQLYVKIRRVLPHFSRQP---DPVVEVTLGESTNLTCVAYGSPMPYV 272

Query: 1232 --KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVE 1285
              +K    D      +  + K  L ++   E     YTC+    L    +TT +KV  + 
Sbjct: 273  KWRKEPATDLTPDNQMPPIGKNVLHLKNVHE--SANYTCIAQSDLGVINTTTYVKVRSLP 330

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345
              P+ V           S++T       +     E +    I  K KH   +    S   
Sbjct: 331  LAPENVQV---------SEITATSVKLTWSYKGPESLAYYVIQHKPKHAHQAYAEISGIT 381

Query: 1346 T----IKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKP-SPPGKPNILEIDSSSI 1397
            T    ++ +       + +   N+ G       V +     KP S P +  +  + S++ 
Sbjct: 382  TMYYMVRSLSPYTEYEFFVIAVNDIGRGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTA 441

Query: 1398 NICWDEPENTGNSTIIYYVVEY-----QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452
             I WDEPE T N  +  Y V Y     Q +   ++ +V N     T+I +L  ++ Y  R
Sbjct: 442  LIQWDEPE-TPNGQVTGYKVYYTTDSGQPMSNWQFQTVDN--NQLTTISDLTAHAIYTIR 498

Query: 1453 AYAVNEV 1459
              A+  V
Sbjct: 499  VQALTSV 505


>UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -
            Caenorhabditis elegans
          Length = 1273

 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 100/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%)

Query: 636  FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
            F  +P+      G   +LEC      PEP ++W    +E+   +     + SD ++    
Sbjct: 135  FRVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI--- 191

Query: 695  LKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
              I  V +   GTY  VA N  GE  S P  L +     E P+  +  K M V  G +V+
Sbjct: 192  --IDPVDRSDSGTYQCVANNMVGERVSNPARLSVF----EKPKFEQEPKDMTVDVGAAVL 245

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
               +V G+P+P ITW + N+P+         D   + I + +   DEG Y   A N  G 
Sbjct: 246  FDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIERVQP-SDEGEYVCYARNPAGT 304

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNE 871
             E SA + V+        PP F  +  + +V   GT      +   P P+  W +    +
Sbjct: 305  LEASAHLRVQ-------APPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQD 357

Query: 872  IISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT- 929
            ++ PS          +    +T  +  ++D G Y C   NSAG S   A + +  + VT 
Sbjct: 358  LLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTG 417

Query: 930  --------FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979
                     ++H  ++     G + IL CQ S   T    W  +   I   D R  I + 
Sbjct: 418  NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSR--ISQH 475

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024
                         D GV  CI K+++  +      T+ +     Q
Sbjct: 476  STGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQ 520



 Score = 93.1 bits (221), Expect = 8e-17
 Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 28/303 (9%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F ++PK   VD G+ +L +CR+   P+P I W  K E  +P     +A ++       
Sbjct: 227 PKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP-MPVTRAYIAKDN------R 279

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            L+I  V+   EG Y   A N  G       L+++     PP          V  G +  
Sbjct: 280 GLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQA----PPSFQTKPADQSVPAGGTAT 335

Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDG-----DTHSITILKPKKVKDEGVYTLK 806
               +VG P P   W K  +     P+   +DG      T ++TI + ++V DEG Y   
Sbjct: 336 FECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQV-DEGAYVCA 394

Query: 807 AENSEG--IAETSAVITVEEPTEEN-AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVP 862
             NS G  +++ +  +T +  T    A+PP  I    Q  T+    +  L  + +  P P
Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454

Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            I+W R+   I  +++ I+Q+  G    L I ++  + D+G Y C+A N  G+S+  A +
Sbjct: 455 GISWLRDGLPIDITDSRISQHSTG---SLHIADL-KKPDTGVYTCIAKNEDGESTWSASL 510

Query: 922 TID 924
           T++
Sbjct: 511 TVE 513



 Score = 93.1 bits (221), Expect = 8e-17
 Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 10/207 (4%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP+F  KP  Q V  G     EC LV  P P   W  +G++ +   +   A         
Sbjct: 316 PPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPT 375

Query: 693 SVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGE---KEPPQVIEPLKSMI 745
             L I  V++  EG Y    +N  G    +A+L +  K  TG    K PP +    ++  
Sbjct: 376 GTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQT 435

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804
           +  G S IL  Q  G P P I+W ++  P+    ++ S   T S+ I   KK  D GVYT
Sbjct: 436 LMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKK-PDTGVYT 494

Query: 805 LKAENSEGIAETSAVITVEEPTEENAE 831
             A+N +G +  SA +TVE+ T  NA+
Sbjct: 495 CIAKNEDGESTWSASLTVEDHT-SNAQ 520



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 126/603 (20%), Positives = 223/603 (36%), Gaps = 62/603 (10%)

Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFT---LISDVKKRTLII--- 1255
            P  ++V   + A L       T  +TWYK  + VI + E+     ++ D     L+    
Sbjct: 37   PIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNS 96

Query: 1256 -RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTLLV--D 1310
             +   + D   Y CV  +     K     ++      D+    R  +  G ++ +L    
Sbjct: 97   GKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMAVLECSP 156

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-A 1369
             + FP+P   W  + K ++     + ++ S   +L I  V+ +D+G Y+    N  G   
Sbjct: 157  PRGFPEPVVSWRKDDKELRIQDMPRYTLHS-DGNLIIDPVDRSDSGTYQCVANNMVGERV 215

Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
                 +++ +KP    +P  + +D  +  + +D          I +  + + +  T    
Sbjct: 216  SNPARLSVFEKPKFEQEPKDMTVDVGAA-VLFDCRVTGDPQPQITWKRKNEPMPVTRAYI 274

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
             K+       I+ ++ +    +  YA N     +AS    + +V      Q+   ++ + 
Sbjct: 275  AKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASA---HLRVQAPPSFQTKPADQSVP 329

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXXXXXXXXX- 1546
               T   E     C   G P P   W ++G++  L  +  + + R               
Sbjct: 330  AGGTATFE-----CTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVR 384

Query: 1547 -----XYKCIAFNDHG--------EVETSCVVG-IQQKPVITISNEDIKQKHKVGDEWLV 1592
                  Y C   N  G        +V T  V G    KP  TI +    Q   VG   ++
Sbjct: 385  QVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAIL 444

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
                 G P P + W ++G  L  D   +  ++  T  + I +LK+  +  YT  A N  G
Sbjct: 445  PCQASGKPTPGISWLRDG--LPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDG 502

Query: 1653 TSSVEVTLKVYDK---------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
             S+   +L V D                PS P  P+I+  ++   V + W  P   G   
Sbjct: 503  ESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIV-NVTDTEVELHWNAPSTSGAGP 561

Query: 1698 LTKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
            +T Y I+ + PD    W  + D     E Y I+ L  +  YMF + A+N  G      S 
Sbjct: 562  ITGYIIQYYSPDLGQTWFNIPDYVASTE-YRIKGLKPSHSYMFVIRAENEKGIGTPSVSS 620

Query: 1757 PIV 1759
             +V
Sbjct: 621  ALV 623



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 135/617 (21%), Positives = 231/617 (37%), Gaps = 82/617 (13%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542
            +E P+ ++         L C  G  P   K+TWY+DG+ + T K    +           
Sbjct: 34   IEHPI-DVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90

Query: 1543 ------------XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----V 1586
                             Y C+A N+HGEV+++     +    + +  ED + + +    +
Sbjct: 91   LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSN-----EGSLKLAMLREDFRVRPRTVQAL 145

Query: 1587 GDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            G E  V       G P P V W K+  +L        T     ++I I  + RS S  Y 
Sbjct: 146  GGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI-IDPVDRSDSGTYQ 204

Query: 1645 IEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
              A+N  G   S    L V++KP   + P  M      +V  + +   D       K   
Sbjct: 205  CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWK--- 261

Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA-----LESEPI 1758
             K+EP       +A  +R +    +Q  +E  EY+    A+NP G  EA     +++ P 
Sbjct: 262  RKNEPMPVTRAYIAKDNRGLRIERVQPSDEG-EYV--CYARNPAGTLEASAHLRVQAPPS 318

Query: 1759 VIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816
                  D  VP+          +   S    W    K G   ++ +   +  +G+  K  
Sbjct: 319  FQTKPADQSVPAGGTATFECTLVGQPSPAYFW---SKEGQQDLL-FPSYVSADGRT-KVS 373

Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876
                     ++++       +     N  G+SL   +    T   T   P++P   +   
Sbjct: 374  PTGTLTIEEVRQVDEGA---YVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHG 430

Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK----IVTVGGSVHEHC-----I 1927
              ++++ +        G S I       K   G SW +    I      + +H      I
Sbjct: 431  HQNQTLMV--------GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHI 482

Query: 1928 ENIKEKDEIIFRISAENTVG-----VSLPTE-----SQSVRLEKHATVPSPPTAPLEIRM 1977
             ++K+ D  ++   A+N  G      SL  E     +Q VR+   +  PS PT P+ + +
Sbjct: 483  ADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIVNV 542

Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035
              + + +  W  P   G  P+ GY I     D+ +T W  +     +T ++ I+ L  +H
Sbjct: 543  TDTEVEL-HWNAPSTSGAGPITGYIIQYYSPDLGQT-WFNIPDYVAST-EYRIKGLKPSH 599

Query: 2036 TYMIRIYARNEIGLSEP 2052
            +YM  I A NE G+  P
Sbjct: 600  SYMFVIRAENEKGIGTP 616



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 107/496 (21%), Positives = 183/496 (36%), Gaps = 43/496 (8%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI-----QFSNHIQLTIDGK 1159
            L P II    +  V++G+ AT         A + W+KDG  +     Q ++H  +   G 
Sbjct: 29   LAPVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGS 88

Query: 1160 KQKLKI---YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD--- 1213
               LK+    +    DAG Y C   N      +   E S+   +   +F + P       
Sbjct: 89   LFLLKVNSGKNGKDSDAGAYYCVASNEH--GEVKSNEGSLKLAMLREDFRVRPRTVQALG 146

Query: 1214 ---AYLTVEIPDETLD--VTWYK--KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
               A L    P    +  V+W K  K+  I+D  ++TL SD     LII      D   Y
Sbjct: 147  GEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD---GNLIIDPVDRSDSGTY 203

Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323
             CV   ++  + +   ++ V E  PK     ++  +  G+ V         PQP   W  
Sbjct: 204  QCVANNMVGERVSNPARLSVFE-KPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITW-- 260

Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383
              +  +    T+  I   +  L I++V+ +D G Y     N  G  +   ++ +   PS 
Sbjct: 261  -KRKNEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSF 319

Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQ---- 1437
              KP    + +        E    G  +  Y+  +   Q++    ++S    TK      
Sbjct: 320  QTKPADQSVPAG--GTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGT 377

Query: 1438 TSIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494
             +I+ ++      +    +N     +S A+       V   T  +  PT+E   +N T  
Sbjct: 378  LTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLM 437

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552
                  L C   G P P ++W RDG    +  ++ +  +                Y CIA
Sbjct: 438  VGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIA 497

Query: 1553 FNDHGEVETSCVVGIQ 1568
             N+ GE   S  + ++
Sbjct: 498  KNEDGESTWSASLTVE 513



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 42/350 (12%)

Query: 864  ITWYRNNE-IISPSETITQN---FDGENIELVITNVDS---EIDSGDYKCVASNSAG--K 914
            ITWY++ + +I+  E +  +    D  ++ L+  N      + D+G Y CVASN  G  K
Sbjct: 61   ITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVK 120

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKE--ISG 969
            S+ G+ + + + +  F +   ++ +   G+  +LEC            W  + KE  I  
Sbjct: 121  SNEGS-LKLAMLREDF-RVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQD 178

Query: 970  MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQ 1024
            M    +  +G             D G  +C+  +           L V E  P+F ++ +
Sbjct: 179  MPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PKFEQEPK 234

Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083
            D  V      + +  +  +    + W+R  E +   +     + RG    L I      D
Sbjct: 235  DMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRG----LRIERVQPSD 290

Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139
            EGEY C  R+ + T E +    V+ PP   T+  +Q V  G  ATFE  L  +      W
Sbjct: 291  EGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFW 350

Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNS 1183
             K+G  ++ F +++  + DG+ +      L I +    D G Y C   NS
Sbjct: 351  SKEGQQDLLFPSYV--SADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNS 398



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 30/223 (13%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQ-DFQMYYDDDNVA 566
           P F  K   +  P G T  FEC + G P P   W +  Q  ++ PS              
Sbjct: 317 PSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTG 376

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626
           TL I EV   D G + C   N+AG + S   L V                          
Sbjct: 377 TLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKV-------------------TTKAVTG 417

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIE 685
           +     PPT     + Q +  GS  +L C+    P P I+WL  G  I + D  IS    
Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHST 477

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
             +H       I ++KK   G YT +A N +GE++    L ++
Sbjct: 478 GSLH-------IADLKKPDTGVYTCIAKNEDGESTWSASLTVE 513



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 101/466 (21%), Positives = 181/466 (38%), Gaps = 60/466 (12%)

Query: 1047 VVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEV 1100
            V W +D + ++ +   +Y     G+   L I      D G Y C+  +      S  A +
Sbjct: 165  VSWRKDDKELRIQDMPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARL 221

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158
            +V E  P+     ++  V+ G    F+  +T GD    + W +    +  +   +  I  
Sbjct: 222  SVFE-KPKFEQEPKDMTVDVGAAVLFDCRVT-GDPQPQITWKRKNEPMPVT---RAYIAK 276

Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
              + L+I      D GEY C      G  + +A L V+ P  +F  + P    VPA   A
Sbjct: 277  DNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPP-SFQTK-PADQSVPAGGTA 334

Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEYTCV 1269
                 +  +     ++ K+   +      + +D + +     TL I +  + D+  Y C 
Sbjct: 335  TFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCA 394

Query: 1270 LLDA------KSTTKLKVEVV------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317
             +++      K+  K+  + V      + PP I    +   +  GS   L       P P
Sbjct: 395  GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376
               W+ +   I     T   I   S  SL I  ++  D G+Y    +N  G +    ++T
Sbjct: 455  GISWLRDGLPIDI---TDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLT 511

Query: 1377 ILDK---------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
            + D                PS P +P I+ +  + + + W+ P  +G   I  Y+++Y  
Sbjct: 512  VEDHTSNAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYS 571

Query: 1422 IDTTE-WISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             D  + W ++ + +  T+  I+ LK + SY F   A NE  I   S
Sbjct: 572  PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPS 617



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 20/135 (14%)

Query: 476 DENNYTQYLQKKLNEKID---KLPVFEKPTSEEQSMAPIFVEKLRPKH-TPD-GSTVQFE 530
           D   Y       + E++    +L VFEKP  E++           PK  T D G+ V F+
Sbjct: 199 DSGTYQCVANNMVGERVSNPARLSVFEKPKFEQE-----------PKDMTVDVGAAVLFD 247

Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
           C+V G P+PQITW R+    +P    + Y   DN   L I  V P D G + C A+N AG
Sbjct: 248 CRVTGDPQPQITWKRKN---EPMPVTRAYIAKDN-RGLRIERVQPSDEGEYVCYARNPAG 303

Query: 591 FASSTTELIVEAPLS 605
              ++  L V+AP S
Sbjct: 304 TLEASAHLRVQAPPS 318



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 2/93 (2%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-GKSWTKIVTVGGSVHE 1924
            PS P   ++   T   V L W  P ++G  PIT YII++ +   G++W  I     S  E
Sbjct: 531  PSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYSPDLGQTWFNIPDYVAST-E 589

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
            + I+ +K     +F I AEN  G+  P+ S ++
Sbjct: 590  YRIKGLKPSHSYMFVIRAENEKGIGTPSVSSAL 622



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 84/403 (20%), Positives = 142/403 (35%), Gaps = 42/403 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK----RGHIR 1072
            P  I    D  V     A L       TA + W +DG+ +   K + +  +     G + 
Sbjct: 31   PVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90

Query: 1073 KLYI---RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
             L +   +N    D G Y C+  +E     S    + +  L  +   R +  +   G  A
Sbjct: 91   LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMA 150

Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              E    +G  + +V W KD  E++  +  + T+      L I   D  D+G Y C   N
Sbjct: 151  VLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLH-SDGNLIIDPVDRSDSGTYQCVANN 209

Query: 1183 ------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235
                  S    +   E+P      + P+ + V           +  D    +TW +K   
Sbjct: 210  MVGERVSNPARLSVFEKPKFE---QEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP 266

Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE 1294
            +  T  + +  D   R L I +    D+ EY C   +   T +    + V+ PP      
Sbjct: 267  MPVTRAY-IAKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKP 323

Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEW-------IVNSKIIKKCKHTKPSIDSKSASLTI 1347
             +  +  G   T        P P   W       ++    +     TK    S + +LTI
Sbjct: 324  ADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKV---SPTGTLTI 380

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKP 1387
            ++V   D G Y     N+ G +  +  + +  K    + P KP
Sbjct: 381  EEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKP 423



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 7/70 (10%)

Query: 524 GSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGT 580
           G     EC    G+P P ++W +    ++  QD   Y  + D N   L+I  V   D+GT
Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELR-IQDMPRYTLHSDGN---LIIDPVDRSDSGT 202

Query: 581 FTCVAKNAAG 590
           + CVA N  G
Sbjct: 203 YQCVANNMVG 212


>UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78;
            Euteleostomi|Rep: Contactin-6 precursor - Homo sapiens
            (Human)
          Length = 1028

 Score = 99.5 bits (237), Expect = 9e-19
 Identities = 188/929 (20%), Positives = 333/929 (35%), Gaps = 68/929 (7%)

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI- 1196
            RW ++G++I F+      +DG    +     D  D G Y C   N   T +    +    
Sbjct: 61   RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTD-QDIGMYQCLATNLLGTILSRKAKLQFA 119

Query: 1197 ---NFTLRLPEFILVPANTDAYLTVEIPDETLDVT--WYKKKSVIEDTEKFTLISDVKKR 1251
               +F  +    + V       L    P    D++  W    + +   E        +  
Sbjct: 120  YIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETG 179

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLK------VE-----VVEFPPKI-VDYEREYRI 1299
             L I K    D   YTC + + ++   ++      V+     + E+ PKI V +    + 
Sbjct: 180  NLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQA 239

Query: 1300 KRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
             + S V L       P P+  W  +  S +  K K++K       A L I   +  D G 
Sbjct: 240  AKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSK-----SQAILEIPNFQQEDEGF 294

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY-YV 1416
            Y+    N  G    +  +     P    K     + S   N+ W E + +G     Y ++
Sbjct: 295  YECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHL-SIYDNLLW-ECKASGKPNPWYTWL 352

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
               + ++  E I ++N T   T    L  + S  ++  A N+  I  A+          +
Sbjct: 353  KNGERLNPEERIQIENGTLIITM---LNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXX 1535
               +SP  +K    +      DI + C     P+  ++W R  + L+ +K  +       
Sbjct: 410  FS-KSPVKKKSFVQV----GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSL 464

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                        Y CIA N  G  + +  + ++++ VIT+     K    VG+  ++   
Sbjct: 465  KIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPS--KMDVTVGESIVLPCQ 522

Query: 1596 IEGIPPPEVI--WYKNGNKLENDK---EYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            +   P  EV+  W+ NG+ ++  K    +     E    + I+ ++  HS KY      T
Sbjct: 523  VSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTT 582

Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710
              + S    + V   P  PE  V + +IS  +  + W+   D+    +  + I+   P +
Sbjct: 583  LESLSAVADIIVRGPPGPPED-VQVEDISSTTSQLSWRAGPDNNS-PIQIFTIQTRTPFS 640

Query: 1711 NRWIKVADVDRDV--ETY--CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766
              W  VA V   +  +TY   +  L+   EY FRV+A N +G  E  E   + ++T   V
Sbjct: 641  VGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSEL-LRTKASV 699

Query: 1767 PSXXXXXXXXXXIDNESVYITW--FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXX 1823
            P                + ITW   P E   G     Y +  +  G   W          
Sbjct: 700  PVVAPVNIHGGGGSRSELVITWESIPEELQNGEG-FGYIIMFRPVGSTTWSKEKVSSVES 758

Query: 1824 ARI----QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879
            +R     + +   + ++ ++   N  G      S   I       P   PR   +   ++
Sbjct: 759  SRFVYRNESIIPLSPFEVKVGVYNNEGEG--SLSTVTIVYSGEDEPQLAPRGTSLQSFSA 816

Query: 1880 RSVTLKWTEPESNGGS-PITNYIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEII 1937
              + + W     N  +  +  Y + + T   K S    + V G+V    I  +K      
Sbjct: 817  SEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYF 876

Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997
              + A NT G      S  V +    + PS P A +  ++  S + +        +  + 
Sbjct: 877  ASVRAYNTAGTG--PSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESE 934

Query: 1998 LLGYNIAIRD--VTKTMWMEVGKVDVNTL 2024
            +LGY I  R    +KT  +E        L
Sbjct: 935  VLGYKILYRQNRQSKTHILETNNTSAELL 963



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 79/328 (24%), Positives = 142/328 (43%), Gaps = 27/328 (8%)

Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
           P+     + S + LEC  +  P PDI+W       +P +   V          ++L+I N
Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGK---VKYSKSQ----AILEIPN 286

Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            ++  EG Y  +A N  G      + K +     PP+  + +++  +   ++++   +  
Sbjct: 287 FQQEDEGFYECIASNLRGRN----LAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKAS 342

Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
           G P P  TW KN + +   P +     +   I+    V D GVY   AEN   I   +A 
Sbjct: 343 GKPNPWYTWLKNGERLN--PEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAE 400

Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
           + V     + ++ P+    F    V+  G I +  +    P  +I+W R  E +  S+ I
Sbjct: 401 LRVLASAPDFSKSPVKKKSF----VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRI 456

Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
               DG    L I N+ +  D+G Y C+A+N  G + +    ++ V++ T +       +
Sbjct: 457 FLLEDG---SLKIYNI-TRSDAGSYTCIATNQFGTAKNTG--SLIVKERTVITVPPSKMD 510

Query: 940 TEEGKTVILECQTSHTVSTK----WYHN 963
              G++++L CQ SH  S +    W+ N
Sbjct: 511 VTVGESIVLPCQVSHDPSIEVVFVWFFN 538



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 68/302 (22%), Positives = 128/302 (42%), Gaps = 35/302 (11%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP + +K +  ++    ++L EC+    P P   WL  GE + P+E I +    +  +  
Sbjct: 317 PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI---ENGTLII 373

Query: 693 SVLKITNVKKFQ---EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
           ++L +++   +Q   E  Y ++  N    A L ++       K P +     K   V+ G
Sbjct: 374 TMLNVSDSGVYQCAAENKYQIIYAN----AELRVLASAPDFSKSPVK-----KKSFVQVG 424

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
             +++  +    PR  I+W +  + +   K +    DG      I +     D G YT  
Sbjct: 425 GDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITR----SDAGSYTCI 480

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI-- 864
           A N  G A+ +  + V+E T     P        ++TV E  +I L  +V+ +P   +  
Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSK-----MDVTVGE--SIVLPCQVSHDPSIEVVF 533

Query: 865 TWYRNNEIISPSETIT--QNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            W+ N ++I   + +   +   GE++ +L+I N+     SG Y C    +    S  A +
Sbjct: 534 VWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLH-HSGKYLCTVQTTLESLSAVADI 592

Query: 922 TI 923
            +
Sbjct: 593 IV 594



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 125/560 (22%), Positives = 213/560 (38%), Gaps = 52/560 (9%)

Query: 649  SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE-GT 707
            S+++L C     P P   W   G +I  D  +S     D       L I +    Q+ G 
Sbjct: 44   SEVILNCAANGYPSPHYRWKQNGTDI--DFTMSYHYRLDG----GSLAINSPHTDQDIGM 97

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP--- 764
            Y  +A N  G   L    K++    E  +  +   ++ VR+G+ V+L   + G P     
Sbjct: 98   YQCLATNLLGTI-LSRKAKLQFAYIEDFET-KTRSTVSVREGQGVVL---LCGPPPHFGD 152

Query: 765  -TITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820
             +  W  N+ P+            +T ++ I K +   D G YT    N E         
Sbjct: 153  LSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEP-SDVGNYTCFITNKEAQRSVQGPP 211

Query: 821  T-VEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            T + + T+      EP + +   + I   +  ++KL      NPVP I+W R +    P 
Sbjct: 212  TPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPG 271

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            +     +      L I N   E D G Y+C+ASN  G++    ++ I      + + +Q 
Sbjct: 272  KV---KYSKSQAILEIPNFQQE-DEGFYECIASNLRGRNLAKGQL-IFYAPPEWEQKIQN 326

Query: 937  SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
            ++       ++ EC+ S      WY   K    ++  E IQ               D GV
Sbjct: 327  TH-LSIYDNLLWECKASGK-PNPWYTWLKNGERLNPEERIQI-ENGTLIITMLNVSDSGV 383

Query: 997  IKCIVKDQ----ETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVVW 1049
             +C  +++      +  L V  + P+F +   K + F     D+ I         A + W
Sbjct: 384  YQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW 443

Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELP 1106
            +R  E ++  K  +  E  G + K+Y  N +  D G Y+CI  ++  TA+ T   +V+  
Sbjct: 444  KRGTETLRQSKRIFLLED-GSL-KIY--NITRSDAGSYTCIATNQFGTAKNTGSLIVKER 499

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEIQFSN---HIQLTIDGKK 1160
              I        V  G       +++     + +  WF +G  I       H +       
Sbjct: 500  TVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESV 559

Query: 1161 QKLKIYDCDLDDAGEYSCEV 1180
              L I +  L  +G+Y C V
Sbjct: 560  GDLMIRNIQLHHSGKYLCTV 579



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 11/175 (6%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV----GG 1920
            PP  P +  V + +S +  L W     N  SPI  + I+ +T     W  + TV     G
Sbjct: 597  PPGPPEDVQVEDISSTTSQLSWRAGPDNN-SPIQIFTIQTRTPFSVGWQAVATVPEILNG 655

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG- 1979
              +   +  +    E  FR+ A N++G+  P+E   + L   A+VP    AP+ I   G 
Sbjct: 656  KTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSEL-LRTKASVPV--VAPVNIHGGGG 712

Query: 1980 --SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032
              S +V+T    PE        GY I  R V  T W +     V + +F  R+ S
Sbjct: 713  SRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNES 767



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +   C+   +PR  I+W R T  ++ S+   +  D     +L I  +   DAG++TC
Sbjct: 424 GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLED----GSLKIYNITRSDAGSYTC 479

Query: 584 VAKNAAGFASSTTELIVE 601
           +A N  G A +T  LIV+
Sbjct: 480 IATNQFGTAKNTGSLIVK 497



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 131/620 (21%), Positives = 230/620 (37%), Gaps = 57/620 (9%)

Query: 732  KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSIT 790
            +EP  VI PL    + + E VIL+    G P P   W +N   +   +      D  S+ 
Sbjct: 30   QEPHDVIFPLD---LSKSE-VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGT 849
            I  P   +D G+Y   A N  G    S    ++    E+ E          ++V+E +G 
Sbjct: 86   INSPHTDQDIGMYQCLATNLLGTI-LSRKAKLQFAYIEDFET----KTRSTVSVREGQGV 140

Query: 850  IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909
            + L          S  W  N+  +   E   +    E   L I  V+   D G+Y C  +
Sbjct: 141  VLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPS-DVGNYTCFIT 199

Query: 910  NSAGKSSHGARVTIDVEKVTFVK---------HLQKSYETEEGKTVILECQTSHTVSTKW 960
            N   + S     T  V++   V             ++ +  +  +V LEC          
Sbjct: 200  NKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDI 259

Query: 961  YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIP 1017
               + + S +  +    + +            D G  +CI  +     +    ++    P
Sbjct: 260  SWRRLDGSPLPGKVKYSKSQAILEIPNFQQE-DEGFYECIASNLRGRNLAKGQLIFYAPP 318

Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076
            E+ +K+Q+  +   D  + E + + +      W ++GE + P++ +   E       L I
Sbjct: 319  EWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEE-RIQIENG----TLII 373

Query: 1077 RNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQK--VNKGNKATFEIEL 1130
               +V D G Y C   ++       AE+ V+   P+       +K  V  G       + 
Sbjct: 374  TMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKP 433

Query: 1131 TKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185
                 A + W +    ++ S  I L  DG    LKIY+    DAG Y+C    + G +K 
Sbjct: 434  NAFPRAAISWKRGTETLRQSKRIFLLEDGS---LKIYNITRSDAGSYTCIATNQFGTAKN 490

Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDV--TWYKKKSVIE---DT 1239
            T  L V+E ++  T+  P  + V       L  ++  D +++V   W+    VI+     
Sbjct: 491  TGSLIVKERTV-ITVP-PSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGV 548

Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298
              F  I       L+IR        +Y C V    +S + +   +V  PP       + +
Sbjct: 549  AHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP---GPPEDVQ 605

Query: 1299 IKRGSDVTLLVDYQAFPQPN 1318
            ++  S  T  + ++A P  N
Sbjct: 606  VEDISSTTSQLSWRAGPDNN 625



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 5/97 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P + +K++  H      + +EC+  G P P  TW +    + P +  Q+    +N  TL+
Sbjct: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI----EN-GTLI 372

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606
           I  +   D+G + C A+N      +  EL V A   D
Sbjct: 373 ITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           S+V+ EC   G P P I+W R      P +   + Y     A L I     ED G + C+
Sbjct: 243 SSVKLECFALGNPVPDISWRRLDGSPLPGK---VKYSKSQ-AILEIPNFQQEDEGFYECI 298

Query: 585 AKNAAGFASSTTELIVEAP 603
           A N  G   +  +LI  AP
Sbjct: 299 ASNLRGRNLAKGQLIFYAP 317


>UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor type,
            sigma isoform 3 variant; n=14; Amniota|Rep: Protein
            tyrosine phosphatase, receptor type, sigma isoform 3
            variant - Homo sapiens (Human)
          Length = 1560

 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 108/530 (20%), Positives = 198/530 (37%), Gaps = 37/530 (6%)

Query: 1473 VIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----GKKLKTAK 1526
            V++E ++ S  P ++   +    E      + C   G P P++TW++D           +
Sbjct: 150  VLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 209

Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV 1586
                                 Y+C+A N  G   +S      +   +      +   H++
Sbjct: 210  IKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEI 269

Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
              G    +T V  G P P V W +    L  + +  +      +V+ + ++K   S+ YT
Sbjct: 270  MPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLELTDVK--DSANYT 323

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
              A ++ G       + V   P  P  P++  E +  S+TI W    D G  +   Y + 
Sbjct: 324  CVAMSSLGVIEAVAQITVKSLPKAPGTPMV-TENTATSITITW----DSGNPDPVSYYVI 378

Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764
            +++  +         D     Y I  L+ N EY   V A N +G  +   SE +V +T  
Sbjct: 379  EYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG--QGPPSESVVTRTGE 436

Query: 1765 DVPSXXXXXXXXXXIDNESVYITW-FPSEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXX 1821
              P+          +   ++ + W  P E NG      + Y +E +     W+       
Sbjct: 437  QAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDS 496

Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
                +  L  + TY  R+ A   +G   P +  D I +      P QP N      +  S
Sbjct: 497  LLTTVGSLLEDETYTVRVLAFTSVGDG-PLS--DPIQVKTQQGVPGQPMNLRAEARSETS 553

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
            +TL W+ P       I  Y + F+  +G    ++         + +E++K   E  FR++
Sbjct: 554  ITLSWSPPRQES---IIKYELLFR--EGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 608

Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
            A +  G+   T      + +  T+ S      +++M+    V+ SW  P+
Sbjct: 609  ARSPQGLGAFTP-----VVRQRTLQSISPKNFKVKMIMKTSVLLSWEFPD 653



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 144/659 (21%), Positives = 253/659 (38%), Gaps = 58/659 (8%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343
            E PP+ +   ++     G   + +      P+P   W    K +   +      D S  A
Sbjct: 56   EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGA 115

Query: 1344 SLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNI--------LEID 1393
             L I+ +    D  +Y+   +N+ G   V   +T+L +   P G PNI        +E  
Sbjct: 116  VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERT 175

Query: 1394 SSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRF 1451
             ++  +C      +GN    I +  ++  +D +     +K +      I++ +     ++
Sbjct: 176  RTATMLC----AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKY 231

Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511
               A N   +  +S    Y +V    ++       P+ +    P  ++ +TC+  G P P
Sbjct: 232  ECVATNSAGVRYSSPANLYVRV---RRVAPRFSILPMSH-EIMPGGNVNITCVAVGSPMP 287

Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
             V W +  + L         R               Y C+A +  G +E    + ++  P
Sbjct: 288  YVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSAN--YTCVAMSSLGVIEAVAQITVKSLP 345

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVI 1630
                    + +         +T   +   P  V +Y    K ++ D  Y I     T+  
Sbjct: 346  KAP-GTPMVTENTATS----ITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRY 400

Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
             I  L  +   +  + A N+ G    S   VT      P+     V  R +S  ++ ++W
Sbjct: 401  SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 460

Query: 1688 KPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            + P++  GL       Y +E   P  N W K  +VD  + T  +  L E+  Y  RV+A 
Sbjct: 461  EEPVEPNGLIRGYRVYYTMEPEHPVGN-WQK-HNVDDSLLT-TVGSLLEDETYTVRVLAF 517

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
              VG  +   S+PI +KT   VP            +  S+ ++W P  +     II Y++
Sbjct: 518  TSVG--DGPLSDPIQVKTQQGVPGQPMNLRAEARSET-SITLSWSPPRQES---IIKYEL 571

Query: 1805 EIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
             + +EG   +             ++ L  NT Y FR+ AR+  G    +T    +   +T
Sbjct: 572  -LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGA-FTP---VVRQRT 626

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK----TVKGKSWTKIVT 1917
            L   S P+NF V      SV L W  P+ N  SP T Y I++      V G++  K++T
Sbjct: 627  LQSIS-PKNFKVKMIMKTSVLLSWEFPD-NYNSP-TPYKIQYNGLTLDVDGRTTKKLIT 682



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 72/264 (27%), Positives = 117/264 (44%), Gaps = 10/264 (3%)

Query: 717 GEASLPIVLKIK-TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775
           G   L +VL +     +EPP+ I+  K  I   G       Q  G+P+P +TW K  K V
Sbjct: 40  GPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 99

Query: 776 KALPTKS---DGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            +   ++   D    ++  ++P +  +DE VY   A+NS G     A +TV    +  + 
Sbjct: 100 NSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 159

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
            P      Q   V+   T  ++   + NP P ITW+++   + PS +  +     +  L 
Sbjct: 160 FPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQ 219

Query: 892 ITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILE 949
           I +   E D G Y+CVA+NSAG + S  A + + V +V      L  S+E   G  V + 
Sbjct: 220 IES-SEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNIT 278

Query: 950 CQT--SHTVSTKWYHNKKEISGMD 971
           C    S     KW    ++++  D
Sbjct: 279 CVAVGSPMPYVKWMQGAEDLTPED 302



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 82/337 (24%), Positives = 140/337 (41%), Gaps = 34/337 (10%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++ + +    G    F CQ  G P+P++TW ++   +   +   + +D+   A L 
Sbjct: 59  PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118

Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628
           I+ +  P D   + CVA+N+ G      E+ V A L+                     D 
Sbjct: 119 IQPLRTPRDENVYECVAQNSVG------EITVHAKLT-----------------VLREDQ 155

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           L    P     P+ + V+      + C     P+P+I W FK  + +P +  S +     
Sbjct: 156 LPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITW-FK--DFLPVDP-SASNGRIK 211

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
            +    L+I + ++  +G Y  VA N  G   S P  L ++     P   I P+   I+ 
Sbjct: 212 QLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM- 270

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            G +V ++   VG+P P + W +  + +    T  D       +L+   VKD   YT  A
Sbjct: 271 PGGNVNITCVAVGSPMPYVKWMQGAEDL----TPEDDMPVGRNVLELTDVKDSANYTCVA 326

Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
            +S G+ E  A ITV+   +    P +  N    IT+
Sbjct: 327 MSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITI 363



 Score = 80.2 bits (189), Expect = 6e-13
 Identities = 75/299 (25%), Positives = 127/299 (42%), Gaps = 23/299 (7%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F K+PK Q    G      C+    P+P + W  KG+++  +      IE D     
Sbjct: 58  PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV--NSQRFETIEFD-ESAG 114

Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748
           +VL+I  ++    E  Y  VA N  GE ++   L +   ++ P   P +    +  +V +
Sbjct: 115 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 174

Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYT 804
             +  +     GNP P ITW K+  PV   P+ S+G    +      ++  +  D+G Y 
Sbjct: 175 TRTATMLCAASGNPDPEITWFKDFLPVD--PSASNGRIKQLRSGALQIESSEETDQGKYE 232

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A NS G+  +S               P F        +   G + +      +P+P +
Sbjct: 233 CVATNSAGVRYSSPANLY---VRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 289

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W +  E ++P + +     G N+ L +T+V    DS +Y CVA +S G     A++T+
Sbjct: 290 KWMQGAEDLTPEDDMPV---GRNV-LELTDVK---DSANYTCVAMSSLGVIEAVAQITV 341



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 92/385 (23%), Positives = 148/385 (38%), Gaps = 32/385 (8%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161
            E PP  I   ++Q    G  A+F  + T GD   R  W K G ++       +  D    
Sbjct: 56   EEPPRFIKEPKDQIGVSGGVASFVCQAT-GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 114

Query: 1162 K-LKIYDCDLD-DAGEYSCEVGNS--------KCTAILTVEEPSINFTLRL-PEFILVP- 1209
              L+I       D   Y C   NS        K T +   + PS    + + P+  +V  
Sbjct: 115  AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 174

Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              T   L     +   ++TW+K    ++ +     I  ++   L I    E DQ +Y CV
Sbjct: 175  TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 234

Query: 1270 LLDA-----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
              ++      S   L V V    P+       + I  G +V +       P P  +W+  
Sbjct: 235  ATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQG 294

Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
            ++ +       P  D       ++  +  D+  Y     ++ G  +    +T+   P  P
Sbjct: 295  AEDLT------PEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAP 348

Query: 1385 GKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK-NITKTQTSIQN 1442
            G P + E  ++SI I WD    +GN   + YYV+EY+         +K +IT T+ SI  
Sbjct: 349  GTPMVTENTATSITITWD----SGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGG 404

Query: 1443 LKTNSSYRFRAYAVNEVDISDASET 1467
            L  NS Y     AVN +     SE+
Sbjct: 405  LSPNSEYEIWVSAVNSIGQGPPSES 429



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 51/218 (23%), Positives = 101/218 (46%), Gaps = 12/218 (5%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P   +V+E+T+ S+T+ W   +S    P++ Y+IE+K+ K +     +    +   +
Sbjct: 345  PKAPGTPMVTENTATSITITW---DSGNPDPVSYYVIEYKS-KSQDGPYQIKEDITTTRY 400

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
             I  +    E    +SA N++G   P+ES   R  + A   +P    ++ RM+ +  ++ 
Sbjct: 401  SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRN--VQARMLSATTMIV 458

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYAR 2044
             W  P    G  + GY +      +       K +V+ +L   +  L E+ TY +R+ A 
Sbjct: 459  QWEEPVEPNGL-IRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAF 517

Query: 2045 NEIG---LSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079
              +G   LS+P++  +  + +PG+  +   E   +T +
Sbjct: 518  TSVGDGPLSDPIQV-KTQQGVPGQPMNLRAEARSETSI 554


>UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precursor;
            n=37; cellular organisms|Rep: Tyrosine-protein
            phosphatase Lar precursor - Drosophila melanogaster
            (Fruit fly)
          Length = 2029

 Score = 99.1 bits (236), Expect = 1e-18
 Identities = 128/610 (20%), Positives = 234/610 (38%), Gaps = 38/610 (6%)

Query: 1451 FRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
            +   A N V D   A  T   Y+  K T    P + +       E    + +TC   G P
Sbjct: 109  YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNP 167

Query: 1510 QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE---TSCVV 1565
             P + W ++  K+  +   Y  +                Y+C+A N  G      T+  V
Sbjct: 168  TPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYV 227

Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625
             +++ P       +   +  +G    ++ +  G P P V W K    L  + E  I  + 
Sbjct: 228  KVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIG-RN 286

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
               +I I+E     S+ YT  A++T G       +KV   P+ P   V + E++  SV +
Sbjct: 287  VLQLINIQE-----SANYTCIAASTLGQIDSVSVVKVQSLPTAPTD-VQISEVTATSVRL 340

Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEYMFRVIAQ 1744
            EW       G E  +Y + +++P N      +++   +  Y  ++ L+   EY F VIA 
Sbjct: 341  EWSYK----GPEDLQYYVIQYKPKNANQA-FSEISGIITMYYVVRALSPYTEYEFYVIAV 395

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804
            N +G      S P    T                + + ++ ITW P E   G  +  YKV
Sbjct: 396  NNIG--RGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQ-VTGYKV 452

Query: 1805 ----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860
                   Q    W            + +L+ +  Y  R+ A   +G   P ++  ++   
Sbjct: 453  YYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAG-PMSTPVQVKAQ 511

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-TVKGKSWTKIVTVG 1919
            + +  PSQP NF  ++    +VTL+WT+P ++    I +Y + +  T   ++  K ++  
Sbjct: 512  QGV--PSQPSNFRATDIGETAVTLQWTKP-THSSENIVHYELYWNDTYANQAHHKRIS-- 566

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
             +   + ++ +         ++A +  G    T    VR +++  VP  P   +      
Sbjct: 567  -NSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQY--VPGAPPRNITAIATS 623

Query: 1980 SNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038
            S  +  SW  P  +     ++ Y +   +V +    E   + +N     + +L     Y 
Sbjct: 624  STTISLSWLPPPVERSNGRIIYYKVFFVEVGRED-DEATTMTLNMTSIVLDELKRWTEYK 682

Query: 2039 IRIYARNEIG 2048
            I + A   +G
Sbjct: 683  IWVLAGTSVG 692



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 74/289 (25%), Positives = 131/289 (45%), Gaps = 21/289 (7%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP   +KP+ Q V  G      C     P P I W   G+++   ++    +E    +  
Sbjct: 35  PPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI-- 92

Query: 693 SVLKITNVKKFQEGT-YTVVAVNREGEA-SLPIVLKIKTGEKEP---PQVIEPLKSMIVR 747
           S+L+I  V+  ++   Y  VA N  G+A S    L I  G+K P   P + +   + ++ 
Sbjct: 93  SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIE 152

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            G +V+++ + +GNP P I W KN   V  + P  S  D      ++  + +D+G Y   
Sbjct: 153 VGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKD--GFLQIENSREEDQGKYECV 210

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT 865
           AENS G   + A        +    PP F    + I+    G+ + L      +P+P + 
Sbjct: 211 AENSMGTEHSKATNLY---VKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVK 267

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
           W + +E ++P   +     G N+ L + N+    +S +Y C+A+++ G+
Sbjct: 268 WMKGSEDLTPENEMP---IGRNV-LQLINIQ---ESANYTCIAASTLGQ 309



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 197/995 (19%), Positives = 370/995 (37%), Gaps = 91/995 (9%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQF--SNHIQLTIDGKKQ 1161
            PPEII + QNQ V  G  A+F     +GD    + W K+G ++    S +  L   G   
Sbjct: 35   PPEIIRKPQNQGVRVGGVASFYCA-ARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGIS 93

Query: 1162 KLKIYD--CDLDDAGEYSCEVGNS-----KCTAILTVEEPS---INFTL--RLPEFILVP 1209
             L+I       DDA  Y C   N         A LT+ E       F +  + P   ++ 
Sbjct: 94   ILRIEPVRAGRDDA-PYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIE 152

Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
                  +T + I + T ++ W K ++ ++    +++L    K   L I    E+DQ +Y 
Sbjct: 153  VGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSL----KDGFLQIENSREEDQGKYE 208

Query: 1268 CVLLDAKST-----TKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            CV  ++  T     T L V+V   PP      E    +  GS++ L       P P+ +W
Sbjct: 209  CVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKW 268

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
            +  S+ +       P  +       ++ +   ++  Y     +  G  D    V +   P
Sbjct: 269  MKGSEDL------TPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLP 322

Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSI 1440
            + P    I E+ ++S+ + W      G   + YYV++Y+  +  +  S +  I      +
Sbjct: 323  TAPTDVQISEVTATSVRLEW---SYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVV 379

Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500
            + L   + Y F   AVN +     S          ETK++S      ++ ++   +  + 
Sbjct: 380  RALSPYTEYEFYVIAVNNIGRGPPSAPATC--TTGETKMESAPRNVQVRTLS---SSTMV 434

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            +T      P  +VT Y+      + +                          +    +  
Sbjct: 435  ITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAY 494

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
            TS   G    PV   + + +  +      +  T +  G     + W K  +  EN   Y 
Sbjct: 495  TSMGAGPMSTPVQVKAQQGVPSQ---PSNFRATDI--GETAVTLQWTKPTHSSENIVHYE 549

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIE-------------ASNTAGTSSVEVTLKVYDKPS 1667
            +   + T   +    + S+S  YT++             A +  G  +    + V  K  
Sbjct: 550  LYWND-TYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQY 608

Query: 1668 KPEGP---VIMREISRESVTIEW-KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723
             P  P   +     S  ++++ W  PP++     +  Y +   E       +   +  ++
Sbjct: 609  VPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGRED-DEATTMTLNM 667

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
             +  + +L    EY   V+A   VG  +   S PI+++T  DVP           +++ S
Sbjct: 668  TSIVLDELKRWTEYKIWVLAGTSVG--DGPRSHPIILRTQEDVPG-DPQDVKATPLNSTS 724

Query: 1784 VYITWFPS-EKNGGSPIIDYKV---EIKQEGKKWK----XXXXXXXXXARIQKLSINTTY 1835
            ++++W P  EK+    I  Y +   E++ EGK +                +  L  +T Y
Sbjct: 725  IHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKY 784

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895
              ++ A    G      +    T G     P+     +  E    S+ L+W  P    G 
Sbjct: 785  SIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIV-SIELEWERPAQTYGE 843

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             +  Y + +  VK ++  + +  G  + +   +N++   E  FR++  N +G+    E+ 
Sbjct: 844  -LRGYRLRW-GVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIG--QETV 899

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWM 2014
             +      T P  P + + IR    +++  +W  P  +     +  Y++      K +  
Sbjct: 900  KIFQTPEGT-PGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFH---KKIDH 955

Query: 2015 EVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIG 2048
             +G     TL K    +L EN  Y+ R+ A  + G
Sbjct: 956  GLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQG 990



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 108/453 (23%), Positives = 169/453 (37%), Gaps = 40/453 (8%)

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVY-DKPSKPEGP 1672
            D E    T   TS++ + ELKR    K  + A  + G    S  + L+   D P  P+  
Sbjct: 657  DDEATTMTLNMTSIV-LDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQD- 714

Query: 1673 VIMREISRESVTIEWKPPLD-DGGLELTKYAIEKHE-PDNNRWIKVADVDRD-VET--YC 1727
            V    ++  S+ + WKPPL+ D    +  Y I   E  D  +         D V+T  + 
Sbjct: 715  VKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFN 774

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN-ESVYI 1786
            +  L  + +Y  +V A    G  +   S  IV+KT   VP            +   S+ +
Sbjct: 775  VTGLQPDTKYSIQVAALTRKGDGD--RSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIEL 832

Query: 1787 TW-FPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845
             W  P++  G       +  +K +  K +          R   L     Y+FR+   N I
Sbjct: 833  EWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHI 892

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEF 1904
            G         KI      TP   P N  +   T   + + W  P   +    IT Y ++F
Sbjct: 893  GIG---QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQF 949

Query: 1905 --KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
              K   G    + +T+  +V      N++E  E IFR+ A    G    ++   V  E+ 
Sbjct: 950  HKKIDHGLGSERNMTLRKAV----FTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETER- 1004

Query: 1963 ATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNI-----AIRDVTKTMWMEV 2016
                    AP+ ++    S      W  P    G  LLGY I     A+ D+       V
Sbjct: 1005 ----DMGRAPMSLQAEATSEQTAEIWWEPVTSRG-KLLGYKIFYTMTAVEDLDDWQTKTV 1059

Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            G  +   L  N+   ++   Y + I AR + GL
Sbjct: 1060 GLTESADL-VNLEKFAQ---YAVAIAARFKNGL 1088



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 83/359 (23%), Positives = 143/359 (39%), Gaps = 39/359 (10%)

Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGP---VIMREISRESVTIE 1686
            R   L+R    ++ +  SN  G    + T+K++  P   P GP   + +R  + + + + 
Sbjct: 872  RFDNLERGVEYEFRVAGSNHIGIG--QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVT 929

Query: 1687 WKPPLDD--GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            W PP  +   G+ +T+Y ++ H+  ++     ++ +  +       L EN EY+FRV A 
Sbjct: 930  WDPPTREHRNGI-ITRYDVQFHKKIDHGL--GSERNMTLRKAVFTNLEENTEYIFRVRAY 986

Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG---GSPIID 1801
               G      S+ ++++T  D+               ++  I W P    G   G  I  
Sbjct: 987  TKQGAGPF--SDKLIVETERDM-GRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIF- 1042

Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861
            Y +   ++   W+         A +  L     Y   I AR + G        +K+T+  
Sbjct: 1043 YTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLG---RLSEKVTV-- 1097

Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK------GKSWTKI 1915
             + P   P N    + ++ S+TL W+ P     +P+ NY I F  +K      G S T+I
Sbjct: 1098 RIKPEDVPLNLRAHDVSTHSMTLSWSPPIRL--TPV-NYKISFDAMKVFVDSQGFSQTQI 1154

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENT--VGVSLPTESQSVRLEKHATVPSPPTAP 1972
            V     + +H +     K   I  +S   T  V VS      S R     TV +   AP
Sbjct: 1155 VPKREIILKHYV-----KTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAP 1208



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 32/294 (10%)

Query: 818  AVITVEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
            +++T   PT  + A PP  I + Q   V+  G          +P PSI W +N + +S +
Sbjct: 20   SLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGT 79

Query: 877  E---TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTI---DVEKVT 929
            +   T+ +   G +I L I  V +  D   Y+CVA N  G + S  A +TI   D     
Sbjct: 80   QSRYTVLEQPGGISI-LRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAG 138

Query: 930  F--VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985
            F  +     +   E G TV++ C+   + T +  W  N+ ++   + R  +++G      
Sbjct: 139  FPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDG---FLQ 195

Query: 986  XXXXXXXDVGVIKCIVKD-------QETSTMLVVKETIPEFIRKLQDFE--VKEKDVAIL 1036
                   D G  +C+ ++       + T+  + V+   P F R  +     +   ++ + 
Sbjct: 196  IENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLS 255

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
             + + S    V W +  E + P       E    I +  ++  ++ +   Y+CI
Sbjct: 256  CIAVGSPMPHVKWMKGSEDLTP-------ENEMPIGRNVLQLINIQESANYTCI 302


>UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan sulfate
            proteoglycan perlecan; n=4; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to heparan sulfate
            proteoglycan perlecan - Strongylocentrotus purpuratus
          Length = 2331

 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 211/952 (22%), Positives = 342/952 (35%), Gaps = 105/952 (11%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PT   +P+   + EG  +   C     P P + W   G +          + S+      
Sbjct: 819  PTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRW--SGGQ-------GGVLNSESTFENG 869

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            +  I   +   E  Y   A N  G A++  VL + +  + P   I P  S  V +GE VI
Sbjct: 870  LFVIPKARASDEAEYFCEATNSAGMATIRTVLYV-SPSRVPSVTISP-ASESVSEGERVI 927

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
               Q  G+P P  TW + +  + +   + +G      ++     + EGVY   A NS G 
Sbjct: 928  FYCQATGDPAPERTWSRIDGDMPSSAREENG----YLVISAVTYEVEGVYRCTATNSHGS 983

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
              + A IT+   T+    P   I+   EITV +  T  L    T  P P+ITW R     
Sbjct: 984  DYSDAQITIS--TDSRRSPTARIDP-AEITVTQGATQVLRCLTTGVPTPTITWTRG---- 1036

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
              S  ++ N    N  L I N D   D   Y C A+N AG S+  A V I+  +   ++ 
Sbjct: 1037 --SGPLSANQQALNGVLRIINAD-VTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEI 1093

Query: 934  LQKS-YETEEGKTVILECQTSHTVST---KWYH-NKKEISGMDHREIIQEGRXXXXXXXX 988
            L  S Y   +G  + ++C+    + T    W   N   +S   + E+             
Sbjct: 1094 LPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSSNTNDEM------GVLTIMG 1147

Query: 989  XXXXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSET 1044
                + G   C   +     T+T  +  + +P+  I      E +  + A+LE     E 
Sbjct: 1148 VTAENQGAYICTGTNSAGSATATATIRVQGLPQISITPTNPAEFRVGETAVLECVATGEP 1207

Query: 1045 ADVV-W--ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
               V W    +  + +P    ++ E+       YI++ S++D G Y        C AE  
Sbjct: 1208 LPTVQWMVMNNERVYQPIAAAFNMEEESSAMH-YIQSVSMNDAGSY-------MCRAENG 1259

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
               +  E++  L+  +V +G  A F      T     + W +       S  +  T+   
Sbjct: 1260 AGYVEQELL--LRELEVIEGETAVFSCTSPGTPAGYTITWRR------VSQRMPSTVSIS 1311

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
               L I       AG+Y C VGN         ++    + L LP   + P  T      E
Sbjct: 1312 NGLLTIPQARSQYAGQYYCIVGNEHGYQ----QDLVTLYVLVLPSLSISP-TTQTVTAGE 1366

Query: 1220 I------PDETLDVT--WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271
            I       + T  +T  W K    +  T      +      L I   T  D  +Y CV  
Sbjct: 1367 IIRISCFAEGTQPITCEWSKYGGSLPPT------AIQSGGILQISPATATDAGQYRCVCS 1420

Query: 1272 DAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            +      + + V V   P       RE R   GS V         P P   W     ++ 
Sbjct: 1421 NTAGFRDSYMTVRVQVIPTVTAIPARETRAIGGS-VEFSCQATGTPPPQITWEKEDGVL- 1478

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389
              +H        +  L++  + + D G Y     N  G +     + +   P+     N 
Sbjct: 1479 PAQHR-----ITNGVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNT 1533

Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449
                         E  +TG+ T    VV + ++++   ISV  +   + +I  +  +   
Sbjct: 1534 TVHYIRVGETTTFECLSTGDPT---PVVTWTKVNSEMPISVV-LQGARLTIPQVSLSDVG 1589

Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509
             +R  A N V  S  S+   Y +   +  +   T   P+          +E +C+ GG P
Sbjct: 1590 FYRCTATNIVG-SRTSQVFLYVQAAPQLTVVPSTRTAPV-------GSTLEFSCLAGGFP 1641

Query: 1510 QPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
             P++TW++D   L      Y+ +                Y CIA N  G  E
Sbjct: 1642 TPEITWHKDDGDLPD---NYQIDNGLLTITNVKEADEGTYVCIATNQGGSTE 1690



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 81/317 (25%), Positives = 136/317 (42%), Gaps = 29/317 (9%)

Query: 640  PKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698
            P+   V EG  +   CR ++  P   IAW  + +  +P         ++   +  +L I 
Sbjct: 734  PQTVEVPEGETVQFVCRGISQTPAYTIAWS-RSDGTLP---------TNARDFMGILTID 783

Query: 699  NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758
             V+    G Y  +  N+   A     L + +  +EP   IEP + + + +G+ V      
Sbjct: 784  TVRLSDAGQYVCMGSNQRDTADAYATLIVTSSVQEPTVRIEP-RFIRITEGDRVEFRCIA 842

Query: 759  VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
             GNP PT+ W      V  L ++S  + + + ++   +  DE  Y  +A NS G+A    
Sbjct: 843  TGNPTPTLRWSGGQGGV--LNSESTFE-NGLFVIPKARASDEAEYFCEATNSAGMATIRT 899

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878
            V+ V      +  P + I+   E +V E   +    + T +P P  TW R +  + PS  
Sbjct: 900  VLYV----SPSRVPSVTISPASE-SVSEGERVIFYCQATGDPAPERTWSRIDGDM-PSSA 953

Query: 879  ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--DVEKVTFVKHLQK 936
                   EN  LVI+ V  E++ G Y+C A+NS G     A++TI  D  +    +    
Sbjct: 954  -----REENGYLVISAVTYEVE-GVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPA 1007

Query: 937  SYETEEGKTVILECQTS 953
                 +G T +L C T+
Sbjct: 1008 EITVTQGATQVLRCLTT 1024



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 193/968 (19%), Positives = 355/968 (36%), Gaps = 102/968 (10%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH 787
            TG++ P  +  P ++  V  G +++   ++ GN   +  W + + +P+        G T+
Sbjct: 632  TGDRIPTVIASPTEASSVLGG-TIVFQVRITGN-YTSAQWRRADGQPLSPSAYVEPG-TY 688

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
             + I +  +  D G++   A N  G       + V           + IN  Q + V E 
Sbjct: 689  RLQI-RNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMR-----VVINDPQTVEVPEG 742

Query: 848  GTIKLVAR-VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
             T++ V R +++ P  +I W R++  +    T  ++F G    L I  V    D+G Y C
Sbjct: 743  ETVQFVCRGISQTPAYTIAWSRSDGTLP---TNARDFMGI---LTIDTVRLS-DAGQYVC 795

Query: 907  VASNSAGKSSHGAR--VTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYH 962
            + SN    +   A   VT  V++ T V+   +     EG  V   C  +   T + +W  
Sbjct: 796  MGSNQRDTADAYATLIVTSSVQEPT-VRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSG 854

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET-STMLVVKET-IPEFI 1020
             +  +  ++     + G             +            T  T+L V  + +P   
Sbjct: 855  GQGGV--LNSESTFENGLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVT 912

Query: 1021 RKLQDFEVKEKDVAILEVEINSETA-DVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRN 1078
                   V E +  I   +   + A +  W R DG++  P   +   E+ G+   L I  
Sbjct: 913  ISPASESVSEGERVIFYCQATGDPAPERTWSRIDGDM--PSSAR---EENGY---LVISA 964

Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIE-LTK 1132
             +   EG Y C   +    +   A++T+  +       R+   ++     AT  +  LT 
Sbjct: 965  VTYEVEGVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQGATQVLRCLTT 1024

Query: 1133 G--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCT 1186
            G     + W +    +  +   Q  ++G    L+I + D+ D   YSC      G+S  T
Sbjct: 1025 GVPTPTITWTRGSGPLSAN---QQALNGV---LRIINADVTDRDMYSCTATNIAGSSTAT 1078

Query: 1187 AILTVE--EPSINFTLRLPEFILVPA-NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243
            A + +E  E  +   L    +I +   N      +     T  V+W +       +    
Sbjct: 1079 AYVEIERRESPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSSN--- 1135

Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKR 1301
              ++ +   L I   T ++Q  Y C   ++   +T    + V   P   +        + 
Sbjct: 1136 --TNDEMGVLTIMGVTAENQGAYICTGTNSAGSATATATIRVQGLPQISITPTNPAEFRV 1193

Query: 1302 GSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
            G    L       P P  +W+V  N ++ +         +  SA   I+ V   DAG Y 
Sbjct: 1194 GETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYM 1253

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419
             R EN  G+ + E+ +  L+         ++E +++  + C   P      TI +  V  
Sbjct: 1254 CRAENGAGYVEQELLLRELE---------VIEGETAVFS-C-TSPGTPAGYTITWRRVS- 1301

Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            Q + +T  IS   +T  Q         S Y  + Y +   +     +    Y ++  +  
Sbjct: 1302 QRMPSTVSISNGLLTIPQA-------RSQYAGQYYCIVGNEHGYQQDLVTLYVLVLPSLS 1354

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
             SPT +      T    E I ++C   G       W + G  L       ++        
Sbjct: 1355 ISPTTQ------TVTAGEIIRISCFAEGTQPITCEWSKYGGSLPPT--AIQSGGILQISP 1406

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y+C+  N  G  ++   V +Q  P +T      ++   +G     +    G 
Sbjct: 1407 ATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAI--PARETRAIGGSVEFSCQATGT 1464

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            PPP++ W K    L    ++ IT      V+ +  L+     +Y   A+N AG+S     
Sbjct: 1465 PPPQITWEKEDGVL--PAQHRIT----NGVLSLISLRDGDEGRYVCTATNQAGSSKAYAR 1518

Query: 1660 LKVYDKPS 1667
            L ++  P+
Sbjct: 1519 LFLHAAPT 1526



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 70/305 (22%), Positives = 118/305 (38%), Gaps = 31/305 (10%)

Query: 634  PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            PT +  P  +    G  +   C+    P P I W  K + ++P ++          +   
Sbjct: 1438 PTVTAIPARETRAIGGSVEFSCQATGTPPPQITWE-KEDGVLPAQH---------RITNG 1487

Query: 694  VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            VL + +++   EG Y   A N+ G +     L +        Q+        +R GE+  
Sbjct: 1488 VLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTV--QITVNTTVHYIRVGETTT 1545

Query: 754  LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
                  G+P P +TW K N     +P         +TI +   + D G Y   A N  G 
Sbjct: 1546 FECLSTGDPTPVVTWTKVNSE---MPISVVLQGARLTIPQVS-LSDVGFYRCTATNIVGS 1601

Query: 814  AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873
              +   + V+   +    P          T     T++        P P ITW++++   
Sbjct: 1602 RTSQVFLYVQAAPQLTVVP-------STRTAPVGSTLEFSCLAGGFPTPEITWHKDDG-- 1652

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
                 +  N+  +N  L ITNV  E D G Y C+A+N  G + H AR+ +  E + +   
Sbjct: 1653 ----DLPDNYQIDNGLLTITNV-KEADEGTYVCIATNQGGSTEHRARLVVG-ELIPYFVQ 1706

Query: 934  LQKSY 938
            + +SY
Sbjct: 1707 MPQSY 1711



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 147/726 (20%), Positives = 269/726 (37%), Gaps = 94/726 (12%)

Query: 599  IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECR 656
            I+ A ++D      T              +I     P     P + Y+  +G +I ++CR
Sbjct: 1053 IINADVTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEILPYSTYIAIDGDNIQIQCR 1112

Query: 657  LVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715
            +++ IP P ++W                + S+ +    VL I  V    +G Y     N 
Sbjct: 1113 ILSGIPTPTVSW---------SRANGAPLSSNTNDEMGVLTIMGVTAENQGAYICTGTNS 1163

Query: 716  EGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNK 773
             G A+    ++++      PQ+ I P      R GE+ +L     G P PT+ W   NN+
Sbjct: 1164 AGSATATATIRVQG----LPQISITPTNPAEFRVGETAVLECVATGEPLPTVQWMVMNNE 1219

Query: 774  PVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830
             V    A     + ++ ++  ++   + D G Y  +AEN  G  E   ++   E  E   
Sbjct: 1220 RVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRAENGAGYVEQELLLRELEVIE--G 1277

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            E  +F       +    GT    A  T      ITW R ++ +  + +I+         L
Sbjct: 1278 ETAVF-------SCTSPGT---PAGYT------ITWRRVSQRMPSTVSISNGL------L 1315

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
             I    S+  +G Y C+  N  G       VT+ V  +  +     +     G+ + + C
Sbjct: 1316 TIPQARSQY-AGQYYCIVGNEHGYQQD--LVTLYVLVLPSLSISPTTQTVTAGEIIRISC 1372

Query: 951  --QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---E 1005
              + +  ++ +W     +  G      IQ G             D G  +C+  +     
Sbjct: 1373 FAEGTQPITCEW----SKYGGSLPPTAIQSG--GILQISPATATDAGQYRCVCSNTAGFR 1426

Query: 1006 TSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064
             S M V  + IP       ++       V        +    + WE++  ++ P +++  
Sbjct: 1427 DSYMTVRVQVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVL-PAQHRI- 1484

Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPP--EIITRLQNQKVN 1119
                G +  + +R+    DEG Y C   +++ +++      +   P  +I        + 
Sbjct: 1485 --TNGVLSLISLRD---GDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIR 1539

Query: 1120 KGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177
             G   TFE  L+ GD   +V W K  SE+     I + + G   +L I    L D G Y 
Sbjct: 1540 VGETTTFEC-LSTGDPTPVVTWTKVNSEMP----ISVVLQG--ARLTIPQVSLSDVGFYR 1592

Query: 1178 CEVGN---SKCTAILTVEEPSINFTLRLPEFILVP-ANTDAYLTVEIPDETLDVTWYKKK 1233
            C   N   S+ + +    + +   T+ +P     P  +T  +  +     T ++TW+K  
Sbjct: 1593 CTATNIVGSRTSQVFLYVQAAPQLTV-VPSTRTAPVGSTLEFSCLAGGFPTPEITWHKDD 1651

Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIV 1291
              + D  +      +    L I    E D+  Y C+  +   +T+ +  +V  E  P  V
Sbjct: 1652 GDLPDNYQ------IDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVVGELIPYFV 1705

Query: 1292 DYEREY 1297
               + Y
Sbjct: 1706 QMPQSY 1711



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 19/261 (7%)

Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
           L+I N++    G +   A NR G  +  + L++  G+     + +P +++ V +GE+V  
Sbjct: 690 LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEV-VGQAMRVVINDP-QTVEVPEGETVQF 747

Query: 755 SAQVVGN-PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813
             + +   P  TI W +++     LPT +  D   I  +   ++ D G Y     N    
Sbjct: 748 VCRGISQTPAYTIAWSRSDG---TLPTNAR-DFMGILTIDTVRLSDAGQYVCMGSNQRDT 803

Query: 814 AETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           A+  A + V   T    EP + I  RF  IT  ++   + +A  T NP P++ W      
Sbjct: 804 ADAYATLIV---TSSVQEPTVRIEPRFIRITEGDRVEFRCIA--TGNPTPTLRWSGGQGG 858

Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
           +  SE+  +N       L +       D  +Y C A+NSAG ++    + +   +V  V 
Sbjct: 859 VLNSESTFEN------GLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVT 912

Query: 933 HLQKSYETEEGKTVILECQTS 953
               S    EG+ VI  CQ +
Sbjct: 913 ISPASESVSEGERVIFYCQAT 933



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 66/341 (19%), Positives = 130/341 (38%), Gaps = 26/341 (7%)

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP--GKPNILEI-DSSSIN-IC 1400
            L I+ +   DAGI+     N  G    E+ + ++ +        P  +E+ +  ++  +C
Sbjct: 690  LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMRVVINDPQTVEVPEGETVQFVC 749

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
                   G S    Y + +   D T   + ++     T I  ++ + + ++     N+ D
Sbjct: 750  ------RGISQTPAYTIAWSRSDGTLPTNARDFMGILT-IDTVRLSDAGQYVCMGSNQRD 802

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
             +DA     Y  +I  + +Q PTV    + I     + +E  CI  G P P + W     
Sbjct: 803  TADA-----YATLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQG 857

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
             +  +++T+EN                Y C A N  G      V+ +    V +++    
Sbjct: 858  GVLNSESTFEN-GLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVTISPA 916

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
             +    G+  +      G P PE  W    ++++ D     + +E+   + I  +     
Sbjct: 917  SESVSEGERVIFYCQATGDPAPERTW----SRIDGDMP--SSAREENGYLVISAVTYEVE 970

Query: 1641 SKYTIEASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREIS 1679
              Y   A+N+ G+  S  ++T+   D    P   +   EI+
Sbjct: 971  GVYRCTATNSHGSDYSDAQITIST-DSRRSPTARIDPAEIT 1010



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 7/79 (8%)

Query: 522  PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            P GST++F C   G+P P+ITW       K   D    Y  DN   L I  V   D GT+
Sbjct: 1626 PVGSTLEFSCLAGGFPTPEITWH------KDDGDLPDNYQIDN-GLLTITNVKEADEGTY 1678

Query: 582  TCVAKNAAGFASSTTELIV 600
             C+A N  G       L+V
Sbjct: 1679 VCIATNQGGSTEHRARLVV 1697



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 7/79 (8%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G +V+F CQ  G P PQITW ++  ++ P+Q    +   + V +L+   +   D G + C
Sbjct: 1452 GGSVEFSCQATGTPPPQITWEKEDGVL-PAQ----HRITNGVLSLI--SLRDGDEGRYVC 1504

Query: 584  VAKNAAGFASSTTELIVEA 602
             A N AG + +   L + A
Sbjct: 1505 TATNQAGSSKAYARLFLHA 1523



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 7/80 (8%)

Query: 523  DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
            DG  +Q +C++  G P P ++W R       S        +D +  L I  V  E+ G +
Sbjct: 1103 DGDNIQIQCRILSGIPTPTVSWSRANGAPLSSNT------NDEMGVLTIMGVTAENQGAY 1156

Query: 582  TCVAKNAAGFASSTTELIVE 601
             C   N+AG A++T  + V+
Sbjct: 1157 ICTGTNSAGSATATATIRVQ 1176



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 70/331 (21%), Positives = 116/331 (35%), Gaps = 30/331 (9%)

Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEID 1393
            P+       L I     TDAG Y+    N  G  D  M V +   P+    P      I 
Sbjct: 1393 PTAIQSGGILQISPATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAIPARETRAIG 1452

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453
             S    C    + TG        + +++ D     +   IT    S+ +L+     R+  
Sbjct: 1453 GSVEFSC----QATGTPPP---QITWEKEDGV-LPAQHRITNGVLSLISLRDGDEGRYVC 1504

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT--TEPNEDIELTCIFGGVPQP 1511
             A N+   S A     Y ++       +PTV+  +          E     C+  G P P
Sbjct: 1505 TATNQAGSSKA-----YARLFLHA---APTVQITVNTTVHYIRVGETTTFECLSTGDPTP 1556

Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571
             VTW +   ++  +      R               Y+C A N  G   +   + +Q  P
Sbjct: 1557 VVTWTKVNSEMPISVVLQGARLTIPQVSLSDVGF--YRCTATNIVGSRTSQVFLYVQAAP 1614

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631
             +T+      +   VG     + +  G P PE+ W+K+   L ++  Y I       ++ 
Sbjct: 1615 QLTVVPST--RTAPVGSTLEFSCLAGGFPTPEITWHKDDGDLPDN--YQI----DNGLLT 1666

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            I  +K +    Y   A+N  G++     L V
Sbjct: 1667 ITNVKEADEGTYVCIATNQGGSTEHRARLVV 1697



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 5/93 (5%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF--RQTAIIKP-SQDFQM 558
            T   Q +  I +    P     G T   EC   G P P + W       + +P +  F M
Sbjct: 1172 TIRVQGLPQISITPTNPAEFRVGETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNM 1231

Query: 559  YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
              ++++ A   I+ V   DAG++ C A+N AG+
Sbjct: 1232 --EEESSAMHYIQSVSMNDAGSYMCRAENGAGY 1262



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 8/185 (4%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541
            PTV       T      +E +C   G P P++TW ++   L  A+    N          
Sbjct: 1438 PTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVLP-AQHRITN-GVLSLISLR 1495

Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                  Y C A N  G  +    + +   P + I+        +VG+      +  G P 
Sbjct: 1496 DGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRVGETTTFECLSTGDPT 1555

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P V W K       + E  I+   + + + I ++  S    Y   A+N  G+ + +V L 
Sbjct: 1556 PVVTWTK------VNSEMPISVVLQGARLTIPQVSLSDVGFYRCTATNIVGSRTSQVFLY 1609

Query: 1662 VYDKP 1666
            V   P
Sbjct: 1610 VQAAP 1614



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

Query: 524  GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
            G T  FEC   G P P +TW +  + +  S   Q        A L I +V   D G + C
Sbjct: 1541 GETTTFECLSTGDPTPVVTWTKVNSEMPISVVLQ-------GARLTIPQVSLSDVGFYRC 1593

Query: 584  VAKNAAGFASSTTELIVEA 602
             A N  G  +S   L V+A
Sbjct: 1594 TATNIVGSRTSQVFLYVQA 1612


>UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; n=3;
            Danio rerio|Rep: hypothetical protein LOC553690 - Danio
            rerio
          Length = 981

 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 107/472 (22%), Positives = 184/472 (38%), Gaps = 32/472 (6%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            F+K+PK Q    G   +L C +        +W+  GE +   E           +    L
Sbjct: 1    FTKEPKPQDALHGRSAMLRCEVNDPQGVSYSWIQNGEPVTNSER--------RFLDGGNL 52

Query: 696  KITNVKK-FQEGTYTVVAVNR---EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            K T + +    G +  +A      E E +      IK  E     +  P     ++    
Sbjct: 53   KFTAIDRTLDSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQ 112

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            VIL   + G PRPT  W K+   +     K +    S+T+L      D G+Y   A+N+ 
Sbjct: 113  VILRCNIDGYPRPTNRWFKDGTQITEKNYKINNKERSVTLLNASP-DDNGLYHCCAKNAA 171

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G   +S   T+    +   +P   + + +++ V +        + T  P+P++ WY  NE
Sbjct: 172  GQVCSSDNFTLNIIDKSFPQP---LVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENE 228

Query: 872  II-SPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEK 927
            ++ + S T    + F   N  L+IT V  + ++G YKCVA    G   S  A + I  E 
Sbjct: 229  LVANKSRTGHFIRVFILSNGSLLITQV-KQRNTGLYKCVAQGPRGPPVSLEASLRI-AEI 286

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
               +    + +  +  + V       H     W+    +    DH  + Q+G        
Sbjct: 287  EDMMAKQSRVFSADSLERVTCRAPYGHPQPEVWWERAGQ-RVPDHGRVFQKGH--DLIFS 343

Query: 988  XXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE- 1043
                 D G+  C  ++   Q+   + V   T PE+++K  D +++E     L     +  
Sbjct: 344  PTHGEDSGIYTCFAQNKAGQKKQELTVTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANP 403

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095
               V W R+ + I  +  ++     G +R   I N  V+D   YSC  R E+
Sbjct: 404  EPQVTWYRNLQPISAEDVRFKLFSNGTLR---INNVEVYDGHMYSCESRTEA 452



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 86/380 (22%), Positives = 150/380 (39%), Gaps = 39/380 (10%)

Query: 1034 AILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092
            A+L  E+N  +     W ++GE +   + +  F   G+++   I  T   D G + CI  
Sbjct: 16   AMLRCEVNDPQGVSYSWIQNGEPVTNSERR--FLDGGNLKFTAIDRTL--DSGNFQCIAS 71

Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVN-KGNKATFEIELTKGDALV-----------RWF 1140
              S   E    E    I   L++  V+ K  ++  EI+ +    L            RWF
Sbjct: 72   KNSTGEEERTAETSFNI-KWLESGAVSLKSPESVAEIQSSSQVILRCNIDGYPRPTNRWF 130

Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK---CTA---ILTVEEP 1194
            KDG++I   N+    I+ K++ + + +   DD G Y C   N+    C++    L + + 
Sbjct: 131  KDGTQITEKNY---KINNKERSVTLLNASPDDNGLYHCCAKNAAGQVCSSDNFTLNIIDK 187

Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIED---TEKFTLISDVKK 1250
            S    L  PE ++V  N +A    +   E +  V WY +  ++ +   T  F  +  +  
Sbjct: 188  SFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSRTGHFIRVFILSN 247

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307
             +L+I +  + +   Y CV    +    + +  + + E    +    R +       VT 
Sbjct: 248  GSLLITQVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIEDMMAKQSRVFSADSLERVTC 307

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
               Y   PQP   W    + +    H +  +  K   L        D+GIY    +N  G
Sbjct: 308  RAPY-GHPQPEVWWERAGQRVPD--HGR--VFQKGHDLIFSPTHGEDSGIYTCFAQNKAG 362

Query: 1368 HADVEMNVTILDKPSPPGKP 1387
                E+ VT+  KP    KP
Sbjct: 363  QKKQELTVTVATKPEWVQKP 382



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 8/96 (8%)

Query: 513 VEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLV 569
           V KL+P++T    G T    CQ  G P P I W ++   ++  +  FQ   +     +LV
Sbjct: 509 VFKLKPENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMAN----GSLV 564

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPL 604
           I +V  ED G++TC+A N+   A ++ EL +VE P+
Sbjct: 565 IHDVSTEDTGSYTCIAGNSCNIAHTSAELYVVEKPV 600



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 85/393 (21%), Positives = 137/393 (34%), Gaps = 46/393 (11%)

Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535
           D   YT + Q K  +K  +L V         +  P +V+K       +G      C    
Sbjct: 349 DSGIYTCFAQNKAGQKKQELTV-------TVATKPEWVQKPVDSQLEEGRAGFLHCHTRA 401

Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595
            P PQ+TW+R    ++P     + +   +  TL I  V   D   ++C ++  AG  ++ 
Sbjct: 402 NPEPQVTWYRN---LQPISAEDVRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQ 458

Query: 596 TELIVEAP-----------LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644
             + V A                 +                  +   +   F  KP+   
Sbjct: 459 ARVFVLAKGRQTPTIHWMRTGQQDNAACHKAQSSQISVESRVSVFCSVYVVFKLKPENTT 518

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           V +G   +L C+    P P I W  K      D+ +         M    L I +V    
Sbjct: 519 VYQGHTAVLHCQATGDPPPFIQWKKK------DKFLEAGKSRFQKMANGSLVIHDVSTED 572

Query: 705 EGTYTVVAVN----REGEASLPIVLK-----IKTGEKEPPQVIEPLKSMIVRQGESVILS 755
            G+YT +A N        A L +V K     +   EK P ++I+ +   +   G +V   
Sbjct: 573 TGSYTCIAGNSCNIAHTSAELYVVEKPVQHSLSDDEKTPYKMIQTIGLSV---GAAVAYI 629

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
             V+G     + +CK  +  K L    DGD   +  L   +V+  G  T  AE  E +A 
Sbjct: 630 IIVLG----LMFYCKQRRNAKRLQKGQDGDEREVECLN-GEVQQNGHTT--AEIQEEVAL 682

Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848
           T+           + E  L   R    T+   G
Sbjct: 683 TNMAAAGNNKRHSSHESKLQFPRSNLHTITTLG 715



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 72/375 (19%), Positives = 143/375 (38%), Gaps = 23/375 (6%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            I+  S V L  +   +P+P + W  +   I + K+ K  I++K  S+T+      D G+Y
Sbjct: 107  IQSSSQVILRCNIDGYPRPTNRWFKDGTQITE-KNYK--INNKERSVTLLNASPDDNGLY 163

Query: 1359 KLRLENNCGHADVEMNVT--ILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
                +N  G      N T  I+DK  P P  KP  L +  +   +   +        + +
Sbjct: 164  HCCAKNAAGQVCSSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEW 223

Query: 1415 Y---VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471
            Y    +   +  T  +I V  ++     I  +K  ++  ++  A        + E +   
Sbjct: 224  YHENELVANKSRTGHFIRVFILSNGSLLITQVKQRNTGLYKCVAQGPRGPPVSLEAS--- 280

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
              ++  +I+   + K  +  + +  E +     +G  PQP+V W R G+++      ++ 
Sbjct: 281  --LRIAEIED-MMAKQSRVFSADSLERVTCRAPYGH-PQPEVWWERAGQRVPDHGRVFQK 336

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C A N  G+ +    V +  KP      + +  + + G    
Sbjct: 337  GHDLIFSPTHGEDSGIYTCFAQNKAGQKKQELTVTVATKPEWV--QKPVDSQLEEGRAGF 394

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650
            +       P P+V WY+N   +   D  + + +      +RI  ++      Y+ E+   
Sbjct: 395  LHCHTRANPEPQVTWYRNLQPISAEDVRFKLFS---NGTLRINNVEVYDGHMYSCESRTE 451

Query: 1651 AGTSSVEVTLKVYDK 1665
            AG  + +  + V  K
Sbjct: 452  AGRVNAQARVFVLAK 466



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           S V   C ++GYPRP   WF+    I        Y  ++   ++ +    P+D G + C 
Sbjct: 111 SQVILRCNIDGYPRPTNRWFKDGTQITEKN----YKINNKERSVTLLNASPDDNGLYHCC 166

Query: 585 AKNAAGFASST 595
           AKNAAG   S+
Sbjct: 167 AKNAAGQVCSS 177



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 15/141 (10%)

Query: 1548 YKCIAF-NDHGE----VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602
            ++CIA  N  GE     ETS  +   +   +++ + +   + +   + ++   I+G P P
Sbjct: 66   FQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVILRCNIDGYPRP 125

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL 1660
               W+K+G ++  +K Y I  KE++  + +       +  Y   A N AG   SS   TL
Sbjct: 126  TNRWFKDGTQI-TEKNYKINNKERS--VTLLNASPDDNGLYHCCAKNAAGQVCSSDNFTL 182

Query: 1661 KVYDK--PS---KPEGPVIMR 1676
             + DK  P    KPE  V+M+
Sbjct: 183  NIIDKSFPQPLVKPEDLVVMK 203



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%)

Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899
           +  TV +  T  L  + T +P P I W + ++ +   ++  Q     N  LVI +V +E 
Sbjct: 515 ENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKM--ANGSLVIHDVSTE- 571

Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEK 927
           D+G Y C+A NS   +   A + + VEK
Sbjct: 572 DTGSYTCIAGNSCNIAHTSAELYV-VEK 598


>UniRef50_A1L1W0 Cluster: Zgc:158442; n=3; Danio rerio|Rep: Zgc:158442
            - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 523

 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 76/308 (24%), Positives = 141/308 (45%), Gaps = 25/308 (8%)

Query: 1295 REYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
            R+  IK+ G  + L++ +Q  P+P   W  N + +     +  + D+ +  L I++ E  
Sbjct: 221  RQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTI-LFIRRSERK 279

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
            D+G Y ++++         +N+ I+D P PP    ++++   ++ + W  P++ GN  I 
Sbjct: 280  DSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKDNGNCDIT 339

Query: 1414 YYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
             Y ++  +  T EW +V +   +T   + +L   + Y FR YA N V +S     ++   
Sbjct: 340  GYNIQKADKKTMEWYTVFEQYRRTNCVVSDLIMGNEYVFRVYAANMVGLSPEPCLSKDSA 399

Query: 1473 VIKETKI-------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519
             I++T I             ++P    PLK+ +     +  L+C   G+ +PK+TWY++ 
Sbjct: 400  YIQKTGIVYKPPSYKDHDFSEAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNK 459

Query: 1520 KKLKTAKATY---ENRXXXXXXXXX--XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
              + T +A Y    N+                 Y C A ND GE    C + + + P +T
Sbjct: 460  MDI-TNEAKYRMFSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDLVECKLEV-RLPQVT 517

Query: 1575 ISNEDIKQ 1582
               EDIK+
Sbjct: 518  --KEDIKK 523



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 56/187 (29%), Positives = 92/187 (49%), Gaps = 8/187 (4%)

Query: 1567 IQQKPVITISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            I Q+P I +   +++Q    KVG+   +    +G P P+V W KN   L+  K  +I   
Sbjct: 208  IMQRPKIWLPR-NLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLD-PKSVSIRNS 265

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684
            +  +++ I+  +R  S KY ++           V +++ D P  P+   +M ++   +V 
Sbjct: 266  DTDTILFIRRSERKDSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVM-DVWGFNVA 324

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIA 1743
            +EWKPP D+G  ++T Y I+K +     W  V +  R   T C +  L    EY+FRV A
Sbjct: 325  LEWKPPKDNGNCDITGYNIQKADKKTMEWYTVFEQYR--RTNCVVSDLIMGNEYVFRVYA 382

Query: 1744 QNPVGFS 1750
             N VG S
Sbjct: 383  ANMVGLS 389



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 72/312 (23%), Positives = 120/312 (38%), Gaps = 19/312 (6%)

Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812
            E +P      +  P+          I + ++ + W   E+ G + +  Y VE  +EG  +
Sbjct: 97   EPQPAPEPEPVGTPTSEPIGLCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDE 156

Query: 1813 W--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--Q 1868
            W              I+ L      QFR+ A N  G S P T    +TI + +  P    
Sbjct: 157  WIPAFSGLTERTSVIIRDLPTGEKMQFRVRAYNMAGPSAPATLQQAVTIREIMQRPKIWL 216

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-- 1926
            PRN   +       T+    P      P  ++    + +  KS    V++  S  +    
Sbjct: 217  PRNLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKS----VSIRNSDTDTILF 272

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I   + KD   + +  +    +    +  SV ++    VP PP     + + G N+ +  
Sbjct: 273  IRRSERKDSGKYDVQVQ----IENVEDKASVNIQI-VDVPGPPQNLKVMDVWGFNVAL-E 326

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P+ +G   + GYNI   D     W  V +    T    + DL   + Y+ R+YA N 
Sbjct: 327  WKPPKDNGNCDITGYNIQKADKKTMEWYTVFEQYRRT-NCVVSDLIMGNEYVFRVYAANM 385

Query: 2047 IGLS-EPLESDE 2057
            +GLS EP  S +
Sbjct: 386  VGLSPEPCLSKD 397



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 58/240 (24%), Positives = 99/240 (41%), Gaps = 26/240 (10%)

Query: 1380 KPSPPGKPN-------ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVK 1431
            +P P G P        + +I  ++I++ W  PE  G++ +  Y VEY +  + EWI +  
Sbjct: 103  EPEPVGTPTSEPIGLCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDEWIPAFS 162

Query: 1432 NIT-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP--- 1487
             +T +T   I++L T    +FR  A N    S A  T +    I+E  +Q P +  P   
Sbjct: 163  GLTERTSVIIRDLPTGEKMQFRVRAYNMAGPS-APATLQQAVTIREI-MQRPKIWLPRNL 220

Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547
             + +  +  E I L   F G P+P+V+W ++ + L     +  N                
Sbjct: 221  RQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSER-- 278

Query: 1548 YKCIAFNDHGEVETSC-VVGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPE 1603
                   D G+ +    +  ++ K  + I   D+    Q  KV D W     +E  PP +
Sbjct: 279  ------KDSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKD 332



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 4/115 (3%)

Query: 492 IDKLPVFEKPTSEEQ---SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
           I K  +  KP S +    S AP F   L+ +    G      C V G  +P+ITW++   
Sbjct: 401 IQKTGIVYKPPSYKDHDFSEAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNKM 460

Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I     ++M + +  V TL IR+  P D G + C A N +G      +L V  P
Sbjct: 461 DITNEAKYRM-FSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDLVECKLEVRLP 514



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 67/311 (21%), Positives = 123/311 (39%), Gaps = 17/311 (5%)

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
            S+P G + + +IS  +++++W+ P   G  EL  Y +E  +  ++ WI       +  + 
Sbjct: 112  SEPIG-LCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDEWIPAFSGLTERTSV 170

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             I+ L    +  FRV A N  G      S P  ++ A+ +             +     I
Sbjct: 171  IIRDLPTGEKMQFRVRAYNMAG-----PSAPATLQQAVTIREIMQRPKIWLPRNLRQTLI 225

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
                   N    +I ++ + + +    K           I+    +T    R   R + G
Sbjct: 226  KKVGETIN---LVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSERKDSG 282

Query: 1847 TSLPYTS----DDKITIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901
                       +DK ++  + +  P  P+N  V +    +V L+W  P+ NG   IT Y 
Sbjct: 283  KYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKDNGNCDITGYN 342

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQ-SVRL 1959
            I+    K   W  +       +   + ++   +E +FR+ A N VG+S  P  S+ S  +
Sbjct: 343  IQKADKKTMEWYTVFEQYRRTN-CVVSDLIMGNEYVFRVYAANMVGLSPEPCLSKDSAYI 401

Query: 1960 EKHATVPSPPT 1970
            +K   V  PP+
Sbjct: 402  QKTGIVYKPPS 412



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 4/90 (4%)

Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDE 800
           +++I + GE++ L     G PRP ++W KN++P+        + DT +I  ++  + KD 
Sbjct: 222 QTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSERKDS 281

Query: 801 GVYTLKA--ENSEGIAETS-AVITVEEPTE 827
           G Y ++   EN E  A  +  ++ V  P +
Sbjct: 282 GKYDVQVQIENVEDKASVNIQIVDVPGPPQ 311



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
           E P+   PLKS  V  G +  LS  V G  +P ITW KN   +             +  L
Sbjct: 420 EAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNKMDITNEAKYRMFSNQGVLTL 479

Query: 793 KPKK--VKDEGVYTLKAENSEG--IAETSAVITVEEPTEEN 829
           + +K    D GVY  KA N  G  + E    + + + T+E+
Sbjct: 480 EIRKPCPFDGGVYMCKAVNDSGEDLVECKLEVRLPQVTKED 520



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 18/67 (26%), Positives = 33/67 (49%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            + GI  P++ WYKN   + N+ +Y + + +    + I++        Y  +A N +G   
Sbjct: 445  VRGISKPKITWYKNKMDITNEAKYRMFSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDL 504

Query: 1656 VEVTLKV 1662
            VE  L+V
Sbjct: 505  VECKLEV 511



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 5/141 (3%)

Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
           + +CK     + +P  S     +  I++     ++  + ++A N  G +  + +      
Sbjct: 147 VEYCKEGSD-EWIPAFSGLTERTSVIIRDLPTGEKMQFRVRAYNMAGPSAPATLQQAVTI 205

Query: 826 TEENAEPPLFINR-FQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883
            E    P +++ R  ++  +K+ G TI LV      P P ++W +N+E + P     +N 
Sbjct: 206 REIMQRPKIWLPRNLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNS 265

Query: 884 DGENIELVITNVDSEIDSGDY 904
           D + I L I   + + DSG Y
Sbjct: 266 DTDTI-LFIRRSERK-DSGKY 284


>UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila
            melanogaster|Rep: Protein turtle - Drosophila
            melanogaster (Fruit fly)
          Length = 1531

 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 106/453 (23%), Positives = 199/453 (43%), Gaps = 38/453 (8%)

Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            D  IL  + + + T +++W +D   + P      F     +R   IR+    D GEY+CI
Sbjct: 269  DSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRH---EDIGEYTCI 325

Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141
             R+     S TA V      V+ +PP   T+L+ +KV      + E +   G+  VRW++
Sbjct: 326  ARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVI----FSCEAKAMPGNVTVRWYR 381

Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS 1195
            +GS ++    ++  +  +K   L I     DD+G+Y CEV N        +A L+VE P+
Sbjct: 382  EGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPA 441

Query: 1196 -INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254
             + FT  + +++           ++   +   VTW K K ++E  +   ++  +   +L+
Sbjct: 442  KVTFTPTV-QYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVV-MANGSLL 499

Query: 1255 IRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYEREYRIKRGSDVTL--- 1307
              +  E+ Q +Y C   +A+ T      + V V + P   V+ E  Y+ K G  V +   
Sbjct: 500  FTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCD 559

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             ++ +   +P  +W    +  +  +  +  I     ++TI+ +   D G Y+  + N   
Sbjct: 560  ALEAEGTERPTIKW-QRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVA 618

Query: 1368 HADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426
               + +   +++   P    NI  +   SSI + W    + G+     Y + ++E    +
Sbjct: 619  TL-MAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVND 677

Query: 1427 W--ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
            W  ISV     TQ +I  L + ++Y F+    N
Sbjct: 678  WQTISVTPSGSTQVTINGLASGTTYEFQVVGRN 710



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 92/398 (23%), Positives = 161/398 (40%), Gaps = 32/398 (8%)

Query: 633  PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP FS  P+   YV+ G  I+L C+    P P+I W      + P   + +  +      
Sbjct: 252  PPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDG----- 306

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L+I+ ++    G YT +A N EG+ S    + I  G      ++ P  +    +GE 
Sbjct: 307  -TELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGG----AVIMVPPTNQTKLEGEK 361

Query: 752  VILSAQVVGNP-RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            VI S +    P   T+ W +   PV+   AL T+         I+ P K  D G Y  + 
Sbjct: 362  VIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEV 421

Query: 808  ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
             N  G  ++ SA ++VE P +    P +     Q +  +  G ++   + +   +  +TW
Sbjct: 422  TNGIGDPQSASAYLSVEYPAKVTFTPTV-----QYLPFRLAGVVQCYIK-SSPQLQYVTW 475

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             ++  ++ P + +       N  L+ T V+ E   G Y C   N+ G +     + + V 
Sbjct: 476  TKDKRLLEPYQ-MKDIVVMANGSLLFTRVNEE-HQGQYACTPYNAQGTAGASGVMDVLVR 533

Query: 927  K-VTFVKHLQKSYETEEGKTVILECQTSHTVST-----KWYHNKKEISGMDHREIIQEGR 980
            K   F    +  Y+ + G +V + C       T     KW   + E      R  I+   
Sbjct: 534  KPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKIS- 592

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018
                        D G  +C+V + E +T++ V + + E
Sbjct: 593  GGNITIENLRREDFGYYQCVVSN-EVATLMAVTQLVIE 629



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 105/500 (21%), Positives = 177/500 (35%), Gaps = 32/500 (6%)

Query: 1284 VEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            V  PP+  V  E    +  G  + L       P P   W  ++  +         I +  
Sbjct: 249  VHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTV--GIFNDG 306

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
              L I  + + D G Y     N  G       V I         P N  +++   +    
Sbjct: 307  TELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSC 366

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN-LKTNSSYRFRAYAVNEVD 1460
            +     GN T+ +Y       +     +   I K  + I N +K + S ++     N   
Sbjct: 367  EAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTN--G 424

Query: 1461 ISDASETTEYYKVIKETKIQ-SPTVEK-PLKNITTEPNEDIELTCIFGGVPQPK-VTWYR 1517
            I D    + Y  V    K+  +PTV+  P +           + C     PQ + VTW +
Sbjct: 425  IGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGV-------VQCYIKSSPQLQYVTWTK 477

Query: 1518 DGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI--QQKPV 1572
            D + L+  +                        Y C  +N  G    S V+ +  ++ P 
Sbjct: 478  DKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPA 537

Query: 1573 ITISNEDIKQKHKVGD--EWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629
             T+  E + Q+ KVGD  E    A+  EG   P + W +   +   + + N   K     
Sbjct: 538  FTVEPETLYQR-KVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRN-RIKISGGN 595

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK 1688
            I I+ L+R     Y    SN   T      L +  + ++P  P  I  + +  S+T++W 
Sbjct: 596  ITIENLRREDFGYYQCVVSNEVATLMAVTQLVI--EGTQPHAPYNITGKATESSITLQWL 653

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
            P    G      Y I   E   N W  ++          I  L     Y F+V+ +N +G
Sbjct: 654  PGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLG 713

Query: 1749 FSEALESEPIVIKTALDVPS 1768
              + + S+ + ++T  D P+
Sbjct: 714  --DGMMSKVMTVRTLEDAPA 731



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 68/261 (26%), Positives = 109/261 (41%), Gaps = 20/261 (7%)

Query: 684 IESDMHMYCSVLKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
           +  D     + L +TN+++  +G Y   VV +NR+ +               P   + P 
Sbjct: 201 VSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPE 260

Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801
             + V  G+S+IL+ Q  G P P I W K+  PV   PT    +  +   +   + +D G
Sbjct: 261 DIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIG 320

Query: 802 VYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
            YT  A N EG ++ T+ VI           PP    + +     EK      A+     
Sbjct: 321 EYTCIARNGEGQVSHTARVIIAGGAV--IMVPPTNQTKLE----GEKVIFSCEAKAMPGN 374

Query: 861 VPSITWYRN----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KS 915
           V ++ WYR      E+ +    +T   DG    L+I  +  + DSG Y C  +N  G   
Sbjct: 375 V-TVRWYREGSPVREVAALETRVTIRKDG---SLIINPIKPD-DSGQYLCEVTNGIGDPQ 429

Query: 916 SHGARVTIDV-EKVTFVKHLQ 935
           S  A ++++   KVTF   +Q
Sbjct: 430 SASAYLSVEYPAKVTFTPTVQ 450



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 92/395 (23%), Positives = 149/395 (37%), Gaps = 55/395 (13%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G ++   CQ +G P P+I W++    + PS    ++ D   +    IR    ED G +TC
Sbjct: 268 GDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRH---EDIGEYTC 324

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           +A+N  G  S T  +I+       G  + +                  +PPT   K    
Sbjct: 325 IARNGEGQVSHTARVIIA------GGAVIM------------------VPPTNQTKL--- 357

Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEI--VPDENISVAIESDMHMYCSVLKITNV 700
              EG  ++  C   A+P    + W  +G  +  V      V I  D       L I  +
Sbjct: 358 ---EGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKD-----GSLIINPI 409

Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
           K    G Y     N  G+   P         + P +V        +    + ++   +  
Sbjct: 410 KPDDSGQYLCEVTNGIGD---PQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKS 466

Query: 761 NPR-PTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSA 818
           +P+   +TW K+ + ++    K      + ++L  +   + +G Y     N++G A  S 
Sbjct: 467 SPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASG 526

Query: 819 V--ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNEIISP 875
           V  + V +P     EP     R    +V E     L A  T    P+I W R   E ++ 
Sbjct: 527 VMDVLVRKPPAFTVEPETLYQRKVGDSV-EMHCDALEAEGTER--PTIKWQRQEGEQLTE 583

Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
           S+       G NI   I N+  E D G Y+CV SN
Sbjct: 584 SQRNRIKISGGNI--TIENLRRE-DFGYYQCVVSN 615



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 123/643 (19%), Positives = 237/643 (36%), Gaps = 66/643 (10%)

Query: 1284 VEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338
            VEFP     P ++ ++++   + GSD+ + + Y+++P+  +E         K + ++ S 
Sbjct: 152  VEFPNDHPVPYVLQWDKKVS-ETGSDLPIYIWYESYPEHIEEGY-------KGRVSRVSQ 203

Query: 1339 DSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI--LDKPSPPG----KPNIL 1390
            DS   SASL +  +  +D G Y+ ++           N T   LD  +PP       +I+
Sbjct: 204  DSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDII 263

Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
             ++     I   + + T    I++Y  +   +D +  + + N   T+  I  ++      
Sbjct: 264  YVNLGDSIILNCQADGTPTPEILWYK-DANPVDPSPTVGIFN-DGTELRISTIRHEDIGE 321

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP- 1509
            +   A N        + +   +VI         +  P  N T    E +  +C    +P 
Sbjct: 322  YTCIARN-----GEGQVSHTARVIIAG---GAVIMVPPTNQTKLEGEKVIFSCEAKAMPG 373

Query: 1510 QPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-SC 1563
               V WYR+G  ++   A     T                   Y C   N  G+ ++ S 
Sbjct: 374  NVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASA 433

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNIT 1622
             + ++    +T +        ++    +V   I+  P  + V W K+   LE  +  +I 
Sbjct: 434  YLSVEYPAKVTFTPTVQYLPFRLAG--VVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIV 491

Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-DKPS----KPEGPVIMRE 1677
                 S++    +   H  +Y     N  GT+     + V   KP     +PE  +  R+
Sbjct: 492  VMANGSLL-FTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPE-TLYQRK 549

Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
            +  +SV +     L+  G E      ++ E +     +   +        I+ L      
Sbjct: 550  VG-DSVEMHCDA-LEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFG 607

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797
             ++ +  N V    A+ ++ ++  T    P               S+ + W P    G  
Sbjct: 608  YYQCVVSNEVATLMAV-TQLVIEGTQPHAPYNITGKAT-----ESSITLQWLPGYSGGSE 661

Query: 1798 PIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854
               DY +  ++ G   W+          +  I  L+  TTY+F++  RN +G  +     
Sbjct: 662  YKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMM---- 717

Query: 1855 DKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             K+   +TL   P+ PRN  V  +T    +     P+  G  P
Sbjct: 718  SKVMTVRTLEDAPAAPRN--VKAATQPPDSFFQLMPDEAGPKP 758



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSV 1922
            T P  P N +  ++T  S+TL+W    S G     +Y I F+      W  I VT  GS 
Sbjct: 631  TQPHAPYN-ITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGST 689

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976
             +  I  +       F++   N +G  + ++  +VR     T+   P AP  ++
Sbjct: 690  -QVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVR-----TLEDAPAAPRNVK 737



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           +G  V F C+ +  P    + W+R+ + ++     +         +L+I  + P+D+G +
Sbjct: 358 EGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQY 417

Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603
            C   N  G   S++  L VE P
Sbjct: 418 LCEVTNGIGDPQSASAYLSVEYP 440



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 7/82 (8%)

Query: 524 GSTVQFEC---QVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAG 579
           G +V+  C   + EG  RP I W RQ    +  SQ  ++     N+    +R    ED G
Sbjct: 551 GDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRR---EDFG 607

Query: 580 TFTCVAKNAAGFASSTTELIVE 601
            + CV  N      + T+L++E
Sbjct: 608 YYQCVVSNEVATLMAVTQLVIE 629


>UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precursor;
            n=35; Tetrapoda|Rep: Neural cell adhesion molecule 2
            precursor - Homo sapiens (Human)
          Length = 837

 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 138/660 (20%), Positives = 256/660 (38%), Gaps = 45/660 (6%)

Query: 1215 YLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
            + T     E   + WY  +   I  T++  +     +  L I     +D   Y C   DA
Sbjct: 39   FFTCTAIGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDA 98

Query: 1274 KSTTKLKVEVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
            K  T+    V+E   K+   E       K+G D  ++    + P P   W+ +++ +   
Sbjct: 99   KGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTI 158

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKL--RLENNCGHADVEMNVTILDKPSPPGKP-- 1387
               + ++ + + +L I  +  +D GIY+   R+E   G  D    + I++ P     P  
Sbjct: 159  SDNRLAMLANN-NLQILNINKSDEGIYRCEGRVEAR-GEIDFRDIIVIVNVPPAISMPQK 216

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
            +          + +    +      I +    + I+  E   +K  + T+ +++N+  + 
Sbjct: 217  SFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKG-SNTELTVRNIINSD 275

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
               +   A N+   +   E   + +V     +Q   ++  LKN TT  N  + L C   G
Sbjct: 276  GGPYVCRATNK---AGEDEKQAFLQVF----VQPHIIQ--LKNETTYENGQVTLVCDAEG 326

Query: 1508 VPQPKVTWYR--------DGKKLKTAKATYENRXXXXXXXXXX---XXXXXYKCIAFNDH 1556
             P P++TW R        +G K    +   + +                  Y C A +  
Sbjct: 327  EPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRI 386

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G  + S  + I+  P   ISN+ I    + G+   ++  ++  PP  + W ++   L   
Sbjct: 387  GGHQKSMYLDIEYAPKF-ISNQTIYYSWE-GNPINISCDVKSNPPASIHWRRDKLVLPAK 444

Query: 1617 KEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
               N+ T    +  ++ I     +   +Y   A+N  GT   E  L + D PS P G  I
Sbjct: 445  NTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKI 504

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI-QKLNE 1733
            + E+S+ +  + +  P   GG+ +  Y ++  E  +  W  V      V+T  +   L  
Sbjct: 505  I-ELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVR--SHGVQTMVVLNNLEP 561

Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
            N  Y  RV A N  G  +  + E I     +  PS            +  + IT    + 
Sbjct: 562  NTTYEIRVAAVNGKGQGDYSKIE-IFQTLPVREPSPPSIHGQPSSGKSFKLSIT---KQD 617

Query: 1794 NGGSPIIDYKVEIKQEGK--KW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
            +GG+PI++Y V+ + + K  +W +           ++ L      +FR+ A N +G S P
Sbjct: 618  DGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGMKFRLPAANRLGYSEP 677



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 116/562 (20%), Positives = 224/562 (39%), Gaps = 46/562 (8%)

Query: 957  STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKD-----QETSTML 1010
            S  WY+ + E      R ++Q+G              D G+ +C   D     QE + +L
Sbjct: 50   SIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVL 109

Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-W-ERDGEIIKPKKNKYDFEKR 1068
             + + +  F   +   E K+ + A +   ++S  A  V W   + E+     N+      
Sbjct: 110  EIYQKLT-FREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLAN 168

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDES-----CTAEVTVVELPPEIITRLQ--NQKVNKG 1121
             +++   I N +  DEG Y C  R E+         + +V +PP I    +  N    +G
Sbjct: 169  NNLQ---ILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERG 225

Query: 1122 NKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178
             + TF    +   +  + WF++G  I+ +   +  + G   +L + +    D G Y C  
Sbjct: 226  EEMTFSCRASGSPEPAISWFRNGKLIEENE--KYILKGSNTELTVRNIINSDGGPYVCRA 283

Query: 1179 --EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKS 1234
              + G  +  A L V  +P I   ++L        N    L  +   E + ++TW +   
Sbjct: 284  TNKAGEDEKQAFLQVFVQPHI---IQLKNETTYE-NGQVTLVCDAEGEPIPEITWKRAVD 339

Query: 1235 VIEDTE-------KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEF 1286
                TE       +  +       +L I+         Y C         +  + + +E+
Sbjct: 340  GFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKSMYLDIEY 399

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT---KPSIDSKSA 1343
             PK +  +  Y    G+ + +  D ++ P  +  W    K++   K+T   K     +  
Sbjct: 400  APKFISNQTIYYSWEGNPINISCDVKSNPPASIHWR-RDKLVLPAKNTTNLKTYSTGRKM 458

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
             L I    + D G Y     N+ G    E  + + D PS P    I+E+  ++  + +++
Sbjct: 459  ILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNK 518

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462
            P++ G   I +Y V+ +E+ +  W  V++   +T   + NL+ N++Y  R  AVN     
Sbjct: 519  PDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQG 578

Query: 1463 DASETTEYYKVIKETKIQSPTV 1484
            D S+  E ++ +   +   P++
Sbjct: 579  DYSK-IEIFQTLPVREPSPPSI 599



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 85/342 (24%), Positives = 140/342 (40%), Gaps = 31/342 (9%)

Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           TF +    Q   +G D  + CR+ + P P ++WL+  EE+    +  +A+ ++ +     
Sbjct: 116 TFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNN----- 170

Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGES 751
           L+I N+ K  EG Y     V   GE     ++ I      PP +  P KS      +GE 
Sbjct: 171 LQILNINKSDEGIYRCEGRVEARGEIDFRDIIVI---VNVPPAISMPQKSFNATAERGEE 227

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           +  S +  G+P P I+W +N K ++         +++   ++     D G Y  +A N  
Sbjct: 228 MTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKA 287

Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
           G  E  A + V        +P   I + +  T  E G + LV      P+P ITW R  +
Sbjct: 288 GEDEKQAFLQV------FVQP--HIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVD 339

Query: 872 II-------SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
                    SP   I       +  L I +V     SG Y C A++  G   H   + +D
Sbjct: 340 GFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLS-GSGRYDCEAASRIG--GHQKSMYLD 396

Query: 925 VEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNK 964
           +E        Q  Y + EG  + + C  +++   S  W  +K
Sbjct: 397 IEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDK 438



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 95/471 (20%), Positives = 182/471 (38%), Gaps = 37/471 (7%)

Query: 736  QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITI 791
            QV   L  + +  GES   +   +G PR +I W  N +  K + T+      G   S   
Sbjct: 22   QVTISLSKVELSVGESKFFTCTAIGEPR-SIDWY-NPQGEKIISTQRVVVQKGGVRSRLT 79

Query: 792  LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851
            +    ++D G+Y  +A +++G  + + V+       E  +   F         K+    +
Sbjct: 80   IYNANIEDAGIYRCQATDAKGQTQEATVVL------EIYQKLTFREVVSPQEFKQGEDAE 133

Query: 852  LVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
            +V RV+ +P P+++W Y N E+ + S+         N++++  N   + D G Y+C    
Sbjct: 134  VVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNIN---KSDEGIYRCEGRV 190

Query: 911  SAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSHTV--STKWYHNKKE 966
             A        + + V     +   QKS+    E G+ +   C+ S +   +  W+ N K 
Sbjct: 191  EARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKL 250

Query: 967  ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQ 1024
            I   ++ + I +G             D G   C   ++  E      ++  +   I +L+
Sbjct: 251  IE--ENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLK 308

Query: 1025 DFEVKEKDVAILEVEINSETA-DVVWER--DG----EIIKPKKNKYDFEKRGHIRKLYIR 1077
            +    E     L  +   E   ++ W+R  DG    E  K    + + + +     L+I+
Sbjct: 309  NETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIK 368

Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
            +  +   G Y C         + ++   +E  P+ I+        +GN      ++    
Sbjct: 369  DVKLSGSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNP 428

Query: 1135 -ALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGN 1182
             A + W +D   +   N   L     G+K  L+I     +D G Y+C   N
Sbjct: 429  PASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 72/300 (24%), Positives = 117/300 (39%), Gaps = 34/300 (11%)

Query: 628 ILEGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
           ++  +PP  S   K+     + G ++   CR    PEP I+W   G+ I  +EN    ++
Sbjct: 203 VIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLI--EENEKYILK 260

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                  + L + N+     G Y   A N+ GE      L++       P +I+ LK+  
Sbjct: 261 GSN----TELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFV----QPHIIQ-LKNET 311

Query: 746 VRQGESVILSAQVVGNPRPTITWCK----------NNKPVKALPTKSDGDTHSITILKPK 795
             +   V L     G P P ITW +          +  P   +  K    + S+ I K  
Sbjct: 312 TYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHI-KDV 370

Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
           K+   G Y  +A +  G  + S  + +E         P FI+        E   I +   
Sbjct: 371 KLSGSGRYDCEAASRIGGHQKSMYLDIEYA-------PKFISNQTIYYSWEGNPINISCD 423

Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV--DSEIDSGDYKCVASNSAG 913
           V  NP  SI W R ++++ P++  T          +I  +   S+ D G Y C A+N  G
Sbjct: 424 VKSNPPASIHW-RRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 9/189 (4%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            PS P    + E +  +  + + +P+S+GG PI +Y ++ K V  + W KIV   G     
Sbjct: 496  PSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIW-KIVRSHGVQTMV 554

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVM 1984
             + N++       R++A N  G     +    ++E   T+P    +P  I     S    
Sbjct: 555  VLNNLEPNTTYEIRVAAVNGKG-----QGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSF 609

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTK-TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
                T + DGGAP+L Y +  R   K   W+E  KV  N     +  L        R+ A
Sbjct: 610  KLSITKQDDGGAPILEYIVKYRSKDKEDQWLE-KKVQGNKDHIILEHLQWTMGMKFRLPA 668

Query: 2044 RNEIGLSEP 2052
             N +G SEP
Sbjct: 669  ANRLGYSEP 677



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 21/288 (7%)

Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFK-DGSEIQFSNHIQLTIDGKKQKLKIY 1166
            ++   L   +++ G    F          + W+   G +I  +  + +   G + +L IY
Sbjct: 22   QVTISLSKVELSVGESKFFTCTAIGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIY 81

Query: 1167 DCDLDDAGEYSCEVGNSK-----CTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEI 1220
            + +++DAG Y C+  ++K      T +L + ++ +    +   EF       DA +   +
Sbjct: 82   NANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEF---KQGEDAEVVCRV 138

Query: 1221 PDETLD-VTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-LLDAKSTT 1277
                   V+W Y  + V   T     ++ +    L I    + D+  Y C   ++A+   
Sbjct: 139  SSSPAPAVSWLYHNEEV--TTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEI 196

Query: 1278 KLK--VEVVEFPPKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
              +  + +V  PP I   ++ +    +RG ++T        P+P   W  N K+I+  ++
Sbjct: 197  DFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIE--EN 254

Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
             K  +   +  LT++ + N+D G Y  R  N  G  + +  + +  +P
Sbjct: 255  EKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQP 302



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  + F C+  G P P I+WFR   +I   ++ + Y    +   L +R +   D G + C
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLI---EENEKYILKGSNTELTVRNIINSDGGPYVC 281

Query: 584 VAKNAAG 590
            A N AG
Sbjct: 282 RATNKAG 288


>UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kDa
            isoform precursor; n=109; Euteleostomi|Rep: Neural cell
            adhesion molecule 1, 140 kDa isoform precursor - Homo
            sapiens (Human)
          Length = 848

 Score = 97.9 bits (233), Expect = 3e-18
 Identities = 140/691 (20%), Positives = 269/691 (38%), Gaps = 60/691 (8%)

Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI---D 1157
            T V L  +I+       V +      ++     D  + WF    E    N  ++++   D
Sbjct: 16   TAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWND 75

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEV---GNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214
                 L IY+ ++DDAG Y C V     S+  A + V+          P         DA
Sbjct: 76   DSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDA 135

Query: 1215 YLTVEIPDETLDVTWYKKKS---VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC--- 1268
             +  ++         +K K    +++   +F ++S+     L IR   + D+  Y C   
Sbjct: 136  VIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSN---NYLQIRGIKKTDEGTYRCEGR 192

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            +L   +   K    +V  PP I   +         G  VTL+ D + FP+P   W  + +
Sbjct: 193  ILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGE 252

Query: 1327 IIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
             I++ +  +  I S  +S LTIKKV+  D   Y    EN  G  D  +++ +  KP    
Sbjct: 253  QIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY 312

Query: 1386 KPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQ- 1441
              N   +E++      C    E +G+            I +  W  S +NI+  + ++  
Sbjct: 313  VENQTAMELEEQVTLTC----EASGD-----------PIPSITWRTSTRNISSEEKTLDG 357

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASE--TTEYYKVIKET-----KIQ-SPTVEKPLKNITT 1493
            ++   S  R  +  +  +  +DA E   T    + +++     ++Q +P ++ P+   T 
Sbjct: 358  HMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW 417

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX--XXXXXXX 1547
            E N+ + +TC     P   ++W+RDG+ L ++  +    Y                    
Sbjct: 418  EGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476

Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD-EWLVTAVIEGIP--PPEV 1604
            Y C A N  G+     ++ +Q     + S + ++        ++       G+P    + 
Sbjct: 477  YNCTAVNRIGQESLEFIL-VQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKA 535

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
             W   G ++ + K Y+        ++ I  LK   +    + A N  G   +    +   
Sbjct: 536  EWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 595

Query: 1665 KP--SKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            +P   +P  P +  ++  +  +I+      DDGG  +  Y + ++   ++ W     +  
Sbjct: 596  QPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLV-RYRALSSEWKPEIRLPS 654

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
              +   ++ L+ N EY   V+A+N  G S+A
Sbjct: 655  GSDHVMLKSLDWNAEYEVYVVAENQQGKSKA 685



 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 130/655 (19%), Positives = 241/655 (36%), Gaps = 54/655 (8%)

Query: 1226 DVTWYKK--KSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKV 1281
            D++W+    + +  + ++ +++ +D    TL I     DD   Y CV+  +  S ++  V
Sbjct: 51   DISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATV 110

Query: 1282 EVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
             V  F   +  +       + G D  ++ D  +   P   W    + +   K  +  + S
Sbjct: 111  NVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLS 170

Query: 1341 KSASLTIKKVENTDAGIYK----LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS- 1395
             +  L I+ ++ TD G Y+    +         D+++ V +   P+   + NI+   ++ 
Sbjct: 171  NNY-LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNV--PPTIQARQNIVNATANL 227

Query: 1396 --SINICWDE---PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450
              S+ +  D    PE T + T     +E QE D  ++I   +   +Q +I+ +  N    
Sbjct: 228  GQSVTLVCDAEGFPEPTMSWTKDGEQIE-QEEDDEKYIFSDD--SSQLTIKKVDKNDEAE 284

Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510
            +   A N+    DA+   + +   K T +++ T          E  E + LTC   G P 
Sbjct: 285  YICIAENKAGEQDATIHLKVFAKPKITYVENQTA--------MELEEQVTLTCEASGDPI 336

Query: 1511 PKVTWYRDGKKLKTAKATYENR---------XXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
            P +TW    + + + + T +                          Y C A N  G+   
Sbjct: 337  PSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQ 396

Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621
            S  + +Q  P +      +      G++  +T  +   P   + W+++G  L +    NI
Sbjct: 397  SMYLEVQYAPKL---QGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453

Query: 1622 T--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679
                    S + +     +    Y   A N  G  S+E  L   D PS P   +   E  
Sbjct: 454  KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPS--IDQVEPY 511

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIE----KHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
              +  +++  P   GG+ + KY  E      E  +++W    +   +     I  L    
Sbjct: 512  SSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME-GIVTIVGLKPET 570

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
             Y  R+ A N  G  E   +     +     PS           D  S+ +     + +G
Sbjct: 571  TYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGE-DGNSIKVNLI-KQDDG 628

Query: 1796 GSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
            GSPI  Y V  +    +WK             ++ L  N  Y+  + A N+ G S
Sbjct: 629  GSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKS 683



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 93/398 (23%), Positives = 166/398 (41%), Gaps = 36/398 (9%)

Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652
           SS+T  I  A + D G    V             ++       F   P  Q   EG D +
Sbjct: 77  SSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAV 136

Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
           + C +V+   P I W  KG +++  +++   + S+     + L+I  +KK  EGTY    
Sbjct: 137 IVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSN-----NYLQIRGIKKTDEGTYRCEG 191

Query: 713 -VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771
            +   GE +   + ++        Q  + + +     G+SV L     G P PT++W K+
Sbjct: 192 RILARGEINFKDI-QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKD 250

Query: 772 NKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
            + ++            D+  +TI K  K  DE  Y   AEN  G  E  A I +    +
Sbjct: 251 GEQIEQEEDDEKYIFSDDSSQLTIKKVDK-NDEAEYICIAENKAG--EQDATIHL----K 303

Query: 828 ENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
             A+P + ++     + ++E+  + L    + +P+PSITW  +   IS  E   +  DG 
Sbjct: 304 VFAKPKITYVENQTAMELEEQ--VTLTCEASGDPIPSITWRTSTRNISSEE---KTLDGH 358

Query: 887 NIELVITNVDS-------EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939
            +      V S         D+G+Y C ASN+ G+ S    + ++V+    ++     Y 
Sbjct: 359 MVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQS--MYLEVQYAPKLQGPVAVY- 415

Query: 940 TEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975
           T EG  V + C+     + +  W+ + + +   ++  I
Sbjct: 416 TWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453



 Score = 85.4 bits (202), Expect = 2e-14
 Identities = 74/299 (24%), Positives = 126/299 (42%), Gaps = 25/299 (8%)

Query: 628 ILEGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
           ++  +PPT   +        + G  + L C     PEP ++W   GE+I  +E+    I 
Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
           SD     S L I  V K  E  Y  +A N+ GE    I LK+       P++        
Sbjct: 266 SDDS---SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA----KPKITYVENQTA 318

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD----TH---SITILKPKKVK 798
           +   E V L+ +  G+P P+ITW  + + + +     DG     +H   S   LK  +  
Sbjct: 319 MELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYT 378

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
           D G Y   A N+  I + S  + +E       + P+ +  +      E   + +   V  
Sbjct: 379 DAGEYICTASNT--IGQDSQSMYLEVQYAPKLQGPVAVYTW------EGNQVNITCEVFA 430

Query: 859 NPVPSITWYRNNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
            P  +I+W+R+ +++  S  +  + ++  +   +    DSE D G+Y C A N  G+ S
Sbjct: 431 YPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQES 489



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 112/536 (20%), Positives = 218/536 (40%), Gaps = 51/536 (9%)

Query: 1025 DFEVKEKDVAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRK-LYIRNTSVH 1082
            +  V E    + +V  +++  D+ W   +GE + P + +            L I N ++ 
Sbjct: 30   EISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANID 89

Query: 1083 DEGEYSCILRDESCT-AEVTV-VELPPEIITRLQN--QKVNKGNKATFEIELTKG-DALV 1137
            D G Y C++  E  + +E TV V++  +++ +     Q+  +G  A    ++       +
Sbjct: 90   DAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTI 149

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-------NSKCTAILT 1190
             W   G ++     ++  +      L+I      D G Y CE         N K   ++ 
Sbjct: 150  IWKHKGRDVILKKDVRFIVLSNNY-LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIV 208

Query: 1191 VEEPSI-------NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE---DTE 1240
               P+I       N T  L + + +  + + +     P+ T+  +W K    IE   D E
Sbjct: 209  NVPPTIQARQNIVNATANLGQSVTLVCDAEGF-----PEPTM--SWTKDGEQIEQEEDDE 261

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRI 1299
            K+    D  + T  I+K  ++D+ EY C+  +        + +  F  PKI   E +  +
Sbjct: 262  KYIFSDDSSQLT--IKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAM 319

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-----HTKPSIDSKSASLTIKKVENTD 1354
            +    VTL  +    P P+  W  +++ I   +     H      ++ +SLT+K ++ TD
Sbjct: 320  ELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTD 379

Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414
            AG Y     N  G     M + +   P   G   +   + + +NI   E     ++TI +
Sbjct: 380  AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITC-EVFAYPSATISW 438

Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            +  + Q + ++ + ++K       S   +  +S   F  Y    V+     E+ E+  V 
Sbjct: 439  F-RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN-RIGQESLEFILVQ 496

Query: 1475 KETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVP--QPKVTWYRDGKKLKTAK 1526
             +T   SP+++  +P  +      ++ E T   GGVP  + K  W   G+++  +K
Sbjct: 497  ADTP-SSPSIDQVEPYSSTAQVQFDEPEAT---GGVPILKYKAEWRAVGEEVWHSK 548



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 25/79 (31%), Positives = 41/79 (51%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G +V   C  EG+P P ++W +    I+  +D + Y   D+ + L I++V   D   + C
Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287

Query: 584 VAKNAAGFASSTTELIVEA 602
           +A+N AG   +T  L V A
Sbjct: 288 IAENKAGEQDATIHLKVFA 306



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%)

Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
           P A Y  EG+ + + C + A P   I+W F+  +++P  N S  I+       S L++T 
Sbjct: 411 PVAVYTWEGNQVNITCEVFAYPSATISW-FRDGQLLPSSNYS-NIKIYNTPSASYLEVTP 468

Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKS 743
             +   G Y   AVNR G+ SL  +L ++      P +  +EP  S
Sbjct: 469 DSENDFGNYNCTAVNRIGQESLEFIL-VQADTPSSPSIDQVEPYSS 513



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 7/189 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHE 1924
            PS P    V E  S +  +++ EPE+ GG PI  Y  E++ V  + W +K      +  E
Sbjct: 500  PSSPSIDQV-EPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 558

Query: 1925 HCIENIKEKDEIIF--RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
              +  +  K E  +  R++A N  G+   + +   + +     PS P    ++   G++I
Sbjct: 559  GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSI 618

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
             +      + DGG+P+  Y +  R ++ + W    ++   +    ++ L  N  Y + + 
Sbjct: 619  KVNL--IKQDDGGSPIRHYLVRYRALS-SEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVV 675

Query: 2043 ARNEIGLSE 2051
            A N+ G S+
Sbjct: 676  AENQQGKSK 684



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ--MYYDDDNVATLVIREVFPED 577
           +T +G+ V   C+V  YP   I+WFR   ++ PS ++     Y+  + + L +      D
Sbjct: 415 YTWEGNQVNITCEVFAYPSATISWFRDGQLL-PSSNYSNIKIYNTPSASYLEVTPDSEND 473

Query: 578 AGTFTCVAKNAAGFASSTTELIVEA 602
            G + C A N  G   S   ++V+A
Sbjct: 474 FGNYNCTAVNRIG-QESLEFILVQA 497



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 3/131 (2%)

Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAI-IKPSQD-FQMYYDDDNVATLVIREVFPEDAGT 580
           G +  F CQV G  + + I+WF      + P+Q    + ++DD+ +TL I     +DAG 
Sbjct: 34  GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGI 93

Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640
           + CV     G  S  T  +         +  T              D++  +PPT   K 
Sbjct: 94  YKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKH 153

Query: 641 KAQYVDEGSDI 651
           K + V    D+
Sbjct: 154 KGRDVILKKDV 164



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQ---DFQMYYDDD-NVATLVIREVFPEDAGTFT 582
           V   C+  G P P ITW   T  I   +   D  M       V++L ++ +   DAG + 
Sbjct: 325 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 384

Query: 583 CVAKNAAGFASSTTELIVE 601
           C A N  G  S +  L V+
Sbjct: 385 CTASNTIGQDSQSMYLEVQ 403


>UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 protein
            tyrosine kinase 7 isoform a precursor; n=1; Apis
            mellifera|Rep: PREDICTED: similar to PTK7 protein
            tyrosine kinase 7 isoform a precursor - Apis mellifera
          Length = 1112

 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 145/666 (21%), Positives = 269/666 (40%), Gaps = 57/666 (8%)

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
            V +G  V L  +   + R    W  + +P+   P +   D   + I +  ++ D G +  
Sbjct: 38   VAEGSPVRLRCEAQPSSRVKYMWKIDGQPLAPSPRRHQ-DGGDLRITRVNRILDSGNFVC 96

Query: 806  KAENSE-GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A + E G +  S+   ++      A   L   +     ++  G I+L   V  +     
Sbjct: 97   VATHEETGYSIESSPAKIDIQWISEASVQLQQPKLPS-AIRVGGEIELRCHVDGSGDIKY 155

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVT 922
             W+RN E ++ S+ I    + +  +L +    +E DSG Y C+A N AG S       + 
Sbjct: 156  EWFRNREPVARSDRI----EIKKKKLHVHRAVAE-DSGMYNCLAKNDAGSSPKMESFPLI 210

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK-EISGMDHREIIQEGRX 981
            +   +   VK + +    + G+  +L C      S +W+      +   D R + + G  
Sbjct: 211  VSSNETASVKVVPRDLIAKRGEPAVLHCVFEDADSVQWFFKDMGPLETDDERTVFENG-- 268

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ--DFE-VKEKDVAILEV 1038
                       D G   C   D+  ST+    +    ++  L    FE +    VA++  
Sbjct: 269  -TLVIRSAEHRDQGFYSCH-GDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGE 326

Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHI-----------RKLYIRNTSV-HDEGE 1086
            E   + + +  E  G    P    Y  + +GHI             L +    +  D+G 
Sbjct: 327  EQELQVSCL--EPSG---LPPPRVYWRDPKGHIISDSGPVRVQDNTLIVAKARMGEDDGN 381

Query: 1087 YSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV---RWF 1140
            Y+C+  + +   +++   V+  PP +I+  +N  V +G+  T     +  DA V   RW 
Sbjct: 382  YTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWL 441

Query: 1141 KDGSEIQFSN---HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            KDG  ++ S      ++T       L +   DL D G Y+CE+       I + E   + 
Sbjct: 442  KDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFS-ERAGLT 500

Query: 1198 FTLRLPEFILVPANTDAYL--TVEIPDETLDVTWYKKKSVIEDT-EKFTL-ISDVKKRTL 1253
               +L +F   P +    L  T ++P ++   T    K + E + E+F   + D+   TL
Sbjct: 501  VEEKL-KFSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGSGEEFPKHVQDING-TL 558

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
                  E+D+  YTC+  +A+ +    + ++VV  P   +  +       G  V L    
Sbjct: 559  HFNGVLEEDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAA 618

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HA 1369
            +  P+P  +W  +S+ +    +++  +   + SL IK+V  +D G Y     N+ G    
Sbjct: 619  EGDPKPTIQWDRDSR-MNNLNNSRFEV-LGNGSLYIKEVYMSDEGKYGCTAGNSGGLKRE 676

Query: 1370 DVEMNV 1375
            +V++NV
Sbjct: 677  EVQLNV 682



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 132/657 (20%), Positives = 244/657 (37%), Gaps = 59/657 (8%)

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------- 1094
            S     +W+ DG+ + P   ++  +  G +R    R   + D G + C+   E       
Sbjct: 53   SSRVKYMWKIDGQPLAPSPRRH--QDGGDLR--ITRVNRILDSGNFVCVATHEETGYSIE 108

Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-----KGDALVRWFKDGSEIQFS 1149
            S  A++ +  +  E   +LQ  K+    +   EIEL       GD    WF++   +  S
Sbjct: 109  SSPAKIDIQWIS-EASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNREPVARS 167

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS-KCTAILTVEEPSINFTLRL-P 1203
            + I++    KK+KL ++    +D+G Y+C    + G+S K  +   +   +   ++++ P
Sbjct: 168  DRIEI----KKKKLHVHRAVAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVP 223

Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263
              ++      A L     D      ++K    +E  ++ T+  +    TL+IR     DQ
Sbjct: 224  RDLIAKRGEPAVLHCVFEDADSVQWFFKDMGPLETDDERTVFEN---GTLVIRSAEHRDQ 280

Query: 1264 CEYTC----------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
              Y+C            +D +    + +    F P +         ++   V+ L +   
Sbjct: 281  GFYSCHGDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSCL-EPSG 339

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P P   W      I     + P     +  +  K     D G Y    EN  G  D+  
Sbjct: 340  LPPPRVYWRDPKGHI--ISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETDISA 397

Query: 1374 NVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432
             V I   P+    P N+  ++  S+ +           T + ++ + + +  +   +   
Sbjct: 398  QVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTRHR 457

Query: 1433 ITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPT-VEKPLK 1489
            +T    ++  +LK+        YA            +E   +  E K++ SP  V+K L 
Sbjct: 458  VTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFSERAGLTVEEKLKFSPQPVDKRL- 516

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549
                E     ++ C   G   P V W ++G   +  K   +                 Y 
Sbjct: 517  ----ELGSTAKVPCKSQGATNPTVKWIKEGSGEEFPKHVQDINGTLHFNGVLEEDKGRYT 572

Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609
            CIA N  G +  +  + +   P  TI  ++  +  + G   ++    EG P P + W ++
Sbjct: 573  CIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIE-GYPVMLHCAAEGDPKPTIQWDRD 631

Query: 1610 G--NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664
               N L N + + +        + IKE+  S   KY   A N+ G    EV L V D
Sbjct: 632  SRMNNLNNSR-FEVLGNGS---LYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVKD 684



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 128/606 (21%), Positives = 231/606 (38%), Gaps = 62/606 (10%)

Query: 636  FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
            FS  P    V EGS + L C           W   G+ + P            H     L
Sbjct: 29   FSVSPGEHSVAEGSPVRLRCEAQPSSRVKYMWKIDGQPLAPSPR--------RHQDGGDL 80

Query: 696  KITNVKK-FQEGTYTVVAVNREGEASL---PIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            +IT V +    G +  VA + E   S+   P  + I+   +   Q+ +P     +R G  
Sbjct: 81   RITRVNRILDSGNFVCVATHEETGYSIESSPAKIDIQWISEASVQLQQPKLPSAIRVGGE 140

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
            + L   V G+      W +N +PV A   + +     + + +    +D G+Y   A+N  
Sbjct: 141  IELRCHVDGSGDIKYEWFRNREPV-ARSDRIEIKKKKLHVHR-AVAEDSGMYNCLAKNDA 198

Query: 812  GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            G +       +   + E A     +       + ++G    V         S+ W+  + 
Sbjct: 199  GSSPKMESFPLIVSSNETAS----VKVVPRDLIAKRGE-PAVLHCVFEDADSVQWFFKD- 252

Query: 872  IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI----DVEK 927
             + P ET  +    EN  LVI + +   D G Y C         S+   + I    ++  
Sbjct: 253  -MGPLETDDERTVFENGTLVIRSAEHR-DQGFYSCHGDRGESTISYTVDLQIAYLMNLSA 310

Query: 928  VTFVKHLQKSY----ETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXX 983
             +F   L        E +E +   LE          W   K  I        +Q+     
Sbjct: 311  ASFEPLLSSQVAVVGEEQELQVSCLEPSGLPPPRVYWRDPKGHIISDSGPVRVQDN--TL 368

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040
                     D G   C+ ++    T +   VV  T P  I   ++  V E D   +    
Sbjct: 369  IVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTCSY 428

Query: 1041 NSETADVV---WERDGEIIK----PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            +   A V    W +DGE +K    P +++   +  G++  L++++  + D+G Y+C +  
Sbjct: 429  SGMDAPVTHVRWLKDGEPLKESGGPTRHRVT-DHHGNV-TLHLKSADLSDKGGYACEITT 486

Query: 1094 E------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSE 1145
            +      S  A +TV E   +   +  ++++  G+ A    + ++G  +  V+W K+GS 
Sbjct: 487  KGFPPIFSERAGLTVEE-KLKFSPQPVDKRLELGSTAKVPCK-SQGATNPTVKWIKEGSG 544

Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF 1205
             +F  H+Q  I+G      + +   +D G Y+C   N++ +   T+   SI+  +  P+F
Sbjct: 545  EEFPKHVQ-DINGTLHFNGVLE---EDKGRYTCIASNAQGSINHTI---SIDVVI-APKF 596

Query: 1206 ILVPAN 1211
             + P N
Sbjct: 597  TIQPQN 602



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 67/255 (26%), Positives = 111/255 (43%), Gaps = 26/255 (10%)

Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
           +G YT VA N  GE  +   + I T    PP +I   +++ V +G+SV ++    G   P
Sbjct: 379 DGNYTCVAENMAGETDISAQVVIST----PPTLISSPENLSVMEGDSVTMTCSYSGMDAP 434

Query: 765 T--ITWCKNNKPVKAL--PTKSDGDTH--SITI-LKPKKVKDEGVYT--LKAENSEGIAE 815
              + W K+ +P+K    PT+     H  ++T+ LK   + D+G Y   +  +    I  
Sbjct: 435 VTHVRWLKDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFS 494

Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875
             A +TVEE  + + +P   +++  E+      T K+  +      P++ W +       
Sbjct: 495 ERAGLTVEEKLKFSPQP---VDKRLELG----STAKVPCKSQGATNPTVKWIKEGS---- 543

Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935
            E   ++    N  L    V  E D G Y C+ASN+ G  +H   + + V    F    Q
Sbjct: 544 GEEFPKHVQDINGTLHFNGVLEE-DKGRYTCIASNAQGSINHTISIDV-VIAPKFTIQPQ 601

Query: 936 KSYETEEGKTVILEC 950
              E  EG  V+L C
Sbjct: 602 NPTEAIEGYPVMLHC 616



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 103/513 (20%), Positives = 188/513 (36%), Gaps = 41/513 (7%)

Query: 640  PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
            P+      G   +L C  V      + W FK    +  ++     E+        L I +
Sbjct: 223  PRDLIAKRGEPAVLHC--VFEDADSVQWFFKDMGPLETDDERTVFEN------GTLVIRS 274

Query: 700  VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQV 758
             +   +G Y+      E   S  + L+I           EPL  S +   GE   L    
Sbjct: 275  AEHRDQGFYSCHGDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSC 334

Query: 759  V---GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
            +   G P P + W      + +         +++ + K +  +D+G YT  AEN  G  +
Sbjct: 335  LEPSGLPPPRVYWRDPKGHIISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETD 394

Query: 816  TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN--PVPSITWYRNNEII 873
             SA + +       + PP  I+  + ++V E  ++ +    +    PV  + W ++ E +
Sbjct: 395  ISAQVVI-------STPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPL 447

Query: 874  SPSETITQNFDGE---NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
              S   T++   +   N+ L + + D   D G Y C  +          R  + VE+   
Sbjct: 448  KESGGPTRHRVTDHHGNVTLHLKSADLS-DKGGYACEITTKGFPPIFSERAGLTVEEKLK 506

Query: 931  VKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
                      E G T  + C++    +   KW    KE SG +  + +Q+          
Sbjct: 507  FSPQPVDKRLELGSTAKVPCKSQGATNPTVKWI---KEGSGEEFPKHVQDINGTLHFNGV 563

Query: 989  XXXXDVGVIKCIVKDQETS---TMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSET 1044
                D G   CI  + + S   T+ +     P+F I+     E  E    +L      + 
Sbjct: 564  LEE-DKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDP 622

Query: 1045 ADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--CTAEVT 1101
               + W+RD  +     ++++    G    LYI+   + DEG+Y C   +       EV 
Sbjct: 623  KPTIQWDRDSRMNNLNNSRFEVLGNG---SLYIKEVYMSDEGKYGCTAGNSGGLKREEVQ 679

Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134
            +      +  R+ +     G+   F+++L  GD
Sbjct: 680  LNVKDTSVDERVNHLSSTAGDTYRFDMDLEVGD 712



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 42/189 (22%), Positives = 83/189 (43%), Gaps = 11/189 (5%)

Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           FS +P  + ++ GS   + C+      P + W+ +G      E     ++ D++     L
Sbjct: 507 FSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGS----GEEFPKHVQ-DIN---GTL 558

Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755
               V +  +G YT +A N +G  +  I + +    K   Q   P +++   +G  V+L 
Sbjct: 559 HFNGVLEEDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAI---EGYPVMLH 615

Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815
               G+P+PTI W ++++      ++ +   +    +K   + DEG Y   A NS G+  
Sbjct: 616 CAAEGDPKPTIQWDRDSRMNNLNNSRFEVLGNGSLYIKEVYMSDEGKYGCTAGNSGGLKR 675

Query: 816 TSAVITVEE 824
               + V++
Sbjct: 676 EEVQLNVKD 684



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 6/81 (7%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GST +  C+ +G   P + W ++ +     ++F  +  D N  TL    V  ED G +TC
Sbjct: 519 GSTAKVPCKSQGATNPTVKWIKEGS----GEEFPKHVQDIN-GTLHFNGVLEEDKGRYTC 573

Query: 584 VAKNAAGFASSTTEL-IVEAP 603
           +A NA G  + T  + +V AP
Sbjct: 574 IASNAQGSINHTISIDVVIAP 594



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 71/347 (20%), Positives = 127/347 (36%), Gaps = 21/347 (6%)

Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
           T ++ +A + +     T             A ++   PPT    P+   V EG  + + C
Sbjct: 367 TLIVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTC 426

Query: 656 RLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
               +  P   + WL  GE +      +    +D H   + L + +     +G Y    +
Sbjct: 427 SYSGMDAPVTHVRWLKDGEPLKESGGPTRHRVTDHHGNVT-LHLKSADLSDKGGY-ACEI 484

Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773
             +G   +       T E++     +P+   +   G +  +  +  G   PT+ W K   
Sbjct: 485 TTKGFPPIFSERAGLTVEEKLKFSPQPVDKRL-ELGSTAKVPCKSQGATNPTVKWIKEGS 543

Query: 774 PVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
             +      D  G  H   +L+    +D+G YT  A N++G    +  I V    +   +
Sbjct: 544 GEEFPKHVQDINGTLHFNGVLE----EDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQ 599

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
           P    N  + I   E   + L      +P P+I W R++ + + + +  +     N  L 
Sbjct: 600 PQ---NPTEAI---EGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNSRFEVLG--NGSLY 651

Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKS 937
           I  V    D G Y C A NS G      ++ + D      V HL  +
Sbjct: 652 IKEVYMS-DEGKYGCTAGNSGGLKREEVQLNVKDTSVDERVNHLSST 697



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 4/95 (4%)

Query: 508 MAPIF-VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           +AP F ++   P    +G  V   C  EG P+P I W R + +   +      ++     
Sbjct: 592 IAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNS---RFEVLGNG 648

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
           +L I+EV+  D G + C A N+ G      +L V+
Sbjct: 649 SLYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVK 683



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 66/298 (22%), Positives = 117/298 (39%), Gaps = 29/298 (9%)

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            A N  GI    AV  +  P         F     E +V E   ++L      +      W
Sbjct: 2    AVNGNGIPRFKAV-NITSPVFGQDGDLYFSVSPGEHSVAEGSPVRLRCEAQPSSRVKYMW 60

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN-SAGKSSHGARVTIDV 925
              + + ++PS    Q  DG ++   IT V+  +DSG++ CVA++   G S   +   ID+
Sbjct: 61   KIDGQPLAPSPRRHQ--DGGDLR--ITRVNRILDSGNFVCVATHEETGYSIESSPAKIDI 116

Query: 926  EKVTFVK-HLQK---SYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEG 979
            + ++     LQ+         G  + L C    S  +  +W+ N++ ++  D  EI    
Sbjct: 117  QWISEASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNREPVARSDRIEI---- 172

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETST------MLVVKETIPEFIRKL-QDFEVKEKD 1032
            +            D G+  C+ K+   S+       L+V       ++ + +D   K  +
Sbjct: 173  KKKKLHVHRAVAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVPRDLIAKRGE 232

Query: 1033 VAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             A+L   +  +   V W  +D   ++    +  FE       L IR+    D+G YSC
Sbjct: 233  PAVLHC-VFEDADSVQWFFKDMGPLETDDERTVFEN----GTLVIRSAEHRDQGFYSC 285


>UniRef50_Q177W1 Cluster: Factor for adipocyte differentiation; n=2;
            Culicidae|Rep: Factor for adipocyte differentiation -
            Aedes aegypti (Yellowfever mosquito)
          Length = 895

 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 90/385 (23%), Positives = 161/385 (41%), Gaps = 24/385 (6%)

Query: 1611 NKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-P 1666
            N L+    Y NI T   T V     L+R+ + ++ ++A N  G S  S EV  K     P
Sbjct: 249  NDLDQGYGYKNIYTGPDT-VYECVGLRRATTFQFRVKAENENGVSPFSKEVVFKTLPSCP 307

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
            S+P  P +  +I      ++W PP+D GG E+  Y +   E  +    +     ++ E  
Sbjct: 308  SRPTKPQVKGKIHATGFKVKWDPPVDTGGAEINLYHL---EISSGAIYERIYSGKESEA- 363

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             I +L+    Y  RV+ + P G S    S+  ++ T  +VP               +  +
Sbjct: 364  MIDRLSPGTTYQIRVLCEGPGGISAF--SDQSLVTTEPEVPGAPPRPHCNGAPTPYAACL 421

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
             W   + NGG+P+++Y++E++   K              ++ L     Y  ++ A N IG
Sbjct: 422  IWEKPDYNGGAPVLEYEMEVEMTNKSRNSCYRGKDQFCVVKDLRPGEMYTVQVRAINRIG 481

Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906
                ++ +     G    PP+ P++  +   +   +T+ W EP  N G+PI+ YI++  T
Sbjct: 482  AG-GWSEEYSFHAG--AAPPNAPKDLNIILKSPTHLTVIWDEPHCN-GAPISEYILQSST 537

Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966
                           +    ++N+       FR+ A N+ G S  + + S +     T  
Sbjct: 538  SADHPSPPSTE---ELLFQTLKNLAPFTNYHFRVCAVNSAGSSRYSATFSQK-----TPA 589

Query: 1967 SPPTAP-LEIRMVGSNIVMTSWGTP 1990
            +PP  P L    + +  ++  W TP
Sbjct: 590  APPNVPVLGQHKITARSILICWETP 614



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 89/386 (23%), Positives = 160/386 (41%), Gaps = 24/386 (6%)

Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724
            +P  P+ P ++   ++ S+ + W    D+G   ++ Y +E      N  I + +  ++ +
Sbjct: 118  EPDVPKAPTLIAR-TKNSLQLRWNAAADNGA-HISNYILEYDNGKYNGMIHLIN-SQNWK 174

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + + KL+ +  Y+FR+ A N  G S    S+ +   TA + PS            + S+
Sbjct: 175  QFTVNKLHPSTSYIFRLAAVNEYGRSGY--SDMVKYNTAGNPPSVPAPPTLQHATAS-SL 231

Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
             + W   ++   S     ++    +G  +K              L   TT+QFR+ A NE
Sbjct: 232  KLAW---QRRSPSEGFTLQMNDLDQGYGYKNIYTGPDTVYECVGLRRATTFQFRVKAENE 288

Query: 1845 IGTSLPYTSDDKITIGKTLTP-PSQP-RNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902
             G S P++ +    + KTL   PS+P +  V  +  +    +KW  P   GG+ I  Y +
Sbjct: 289  NGVS-PFSKE---VVFKTLPSCPSRPTKPQVKGKIHATGFKVKWDPPVDTGGAEINLYHL 344

Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            E  +  G  + +I +  G   E  I+ +        R+  E   G+S  ++   V  E  
Sbjct: 345  EISS--GAIYERIYS--GKESEAMIDRLSPGTTYQIRVLCEGPGGISAFSDQSLVTTEPE 400

Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022
              VP  P  P              W  P+++GGAP+L Y + +    K+        D  
Sbjct: 401  --VPGAPPRPHCNGAPTPYAACLIWEKPDYNGGAPVLEYEMEVEMTNKSRNSCYRGKDQF 458

Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIG 2048
             +   ++DL     Y +++ A N IG
Sbjct: 459  CV---VKDLRPGEMYTVQVRAINRIG 481



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 2/104 (1%)

Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQT 1438
            +P  P  P ++    +S+ + W+   + G + I  Y++EY        I + N     Q 
Sbjct: 118  EPDVPKAPTLIARTKNSLQLRWNAAADNG-AHISNYILEYDNGKYNGMIHLINSQNWKQF 176

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
            ++  L  ++SY FR  AVNE   S  S+  +Y        + +P
Sbjct: 177  TVNKLHPSTSYIFRLAAVNEYGRSGYSDMVKYNTAGNPPSVPAP 220


>UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62;
           Euteleostomi|Rep: Protein sidekick-1 precursor - Homo
           sapiens (Human)
          Length = 2213

 Score = 97.5 bits (232), Expect = 4e-18
 Identities = 120/443 (27%), Positives = 178/443 (40%), Gaps = 49/443 (11%)

Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592
           +  YPRPQ+TWFR+   I PS    +  ++     LVI      DAG +   A N     
Sbjct: 215 ITSYPRPQVTWFREGHKIIPSNRIAITLENQ----LVILATTTSDAGAYYVQAVNEKNGE 270

Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS-DI 651
           + T+  I  +   D G+  T+                    PT    P  + V  GS + 
Sbjct: 271 NKTSPFIHLSIARDVGTPETMA-------------------PTIVVPPGNRSVVAGSSET 311

Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711
            LEC   A P  D++  +K           V I S +H +   L I+N      G Y   
Sbjct: 312 TLECIASARPVEDLSVTWKRN--------GVRITSGLHSFGRHLTISNPTSADTGPYVCE 363

Query: 712 AVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770
           A    G A  P          EPP    EP   +     E+V +  Q +G P PT+ W K
Sbjct: 364 AA-LPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYK 422

Query: 771 NNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
           +   +  L  P      +  + I K +  +D G++   A N  G  +T   + V      
Sbjct: 423 DAISISRLQNPRYKVLASGGLRIQKLRP-EDSGIFQCFASNEGGEIQTHTYLDVTNIA-- 479

Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGEN 887
               P+F  R  + TV +  T  L   V+  P P+ITW R N I+ S S  I +    E+
Sbjct: 480 ----PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLES 535

Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
             L I  V  + D+G+Y C A+N+ G  S  A  T+ V   T + H  + +   +G T  
Sbjct: 536 GGLQIAPVFIQ-DAGNYTCYAANTEG--SLNASATLTVWNRTSIVHPPEDHVVIKGTTAT 592

Query: 948 LECQTSH--TVSTKWYHNKKEIS 968
           L C  +H   VS ++   K  ++
Sbjct: 593 LHCGATHDPRVSLRYVWKKDNVA 615



 Score = 87.0 bits (206), Expect = 5e-15
 Identities = 107/468 (22%), Positives = 180/468 (38%), Gaps = 30/468 (6%)

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG----PVI 1674
            Y    +    ++ I  L      ++ ++  N  G S    + +V      P       V 
Sbjct: 1122 YEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVT 1181

Query: 1675 MREISRESVTIEWKPPLD---DGGLELTKYAIEKHEPDNNRWIKVADV--DRDVETYCIQ 1729
            +R  S  S+ + W P  D   +G  E   Y I+    D      VA V  DR    + I+
Sbjct: 1182 VRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQS-SAVAQVVSDRLEREFTIE 1240

Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789
            +L E  EY  ++ A N VG      SE +  +T   VPS          + +  + +TW 
Sbjct: 1241 ELEEWMEYELQMQAFNAVGAGPW--SEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWT 1298

Query: 1790 P-SEKNGGSPIIDYKVEIKQEG----KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844
               E++    I+ YK+  + +      +           A +  L     Y+ ++ A   
Sbjct: 1299 SVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTR 1358

Query: 1845 IGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903
            IG  +P T    + + +T    P  P   V  E    SV + W  PE   G  I  Y I 
Sbjct: 1359 IGNGVPSTP---LILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI-ILGYQIA 1414

Query: 1904 FKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962
            ++       T   V VG +V +    ++  +   IFR+SA+   G   P E+  +  EK 
Sbjct: 1415 YRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKR 1474

Query: 1963 ATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVD 2020
               P+PP   L  +  V +  +   W  P  DG +P+  + + +R++ +  W      + 
Sbjct: 1475 ER-PAPPRELLVPQAEVTARSLRLQW-VPGSDGASPIRYFTMQVRELPRGEWQTYSSSIS 1532

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESDEPFKVIPGE 2065
                   +  L    +Y +R+ A N+IG    S   E+    + +PGE
Sbjct: 1533 HEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGE 1580



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 129/541 (23%), Positives = 210/541 (38%), Gaps = 48/541 (8%)

Query: 685  ESDMHMYCSVLK--ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
            +S++  Y S  K  I +++K   G Y  V  NR G A L    +++          +  K
Sbjct: 142  DSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMG-ALLQRKSEVQVAYMGSFMDTDQRK 200

Query: 743  SMIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKALPTKSDGDT-HSITILKPKKVKDE 800
            +  V QG + IL+   +   PRP +TW +     K +P+     T  +  ++      D 
Sbjct: 201  T--VSQGRAAILNLLPITSYPRPQVTWFREGH--KIIPSNRIAITLENQLVILATTTSDA 256

Query: 801  GVYTLKAENSE-GIAETSAVITV----EEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855
            G Y ++A N + G  +TS  I +    +  T E   P + +       V       L   
Sbjct: 257  GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316

Query: 856  VTRNPVP--SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS--NS 911
             +  PV   S+TW RN         IT         L I+N  S  D+G Y C A+   S
Sbjct: 317  ASARPVEDLSVTWKRNGV------RITSGLHSFGRHLTISNPTSA-DTGPYVCEAALPGS 369

Query: 912  AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISG 969
            A + +        +E   F    +     E  +TV + CQ       + +WY +   IS 
Sbjct: 370  AFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISR 429

Query: 970  MDHR--EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKL 1023
            + +   +++  G             D G+ +C   ++    +T T L V    P F ++ 
Sbjct: 430  LQNPRYKVLASG---GLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRP 486

Query: 1024 QDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
             D  V +   AIL  E++ +    + W+R+  I+     +           L I    + 
Sbjct: 487  VDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQ 546

Query: 1083 DEGEYSCIL--RDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VR 1138
            D G Y+C     + S  A  T+ V     I+   ++  V KG  AT     T    + +R
Sbjct: 547  DAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLR 606

Query: 1139 --WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192
              W KD   +  S+  ++ ++ K   L I      D G+YSCE+    GN    A L V 
Sbjct: 607  YVWKKDNVALTPSSTSRIVVE-KDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVI 665

Query: 1193 E 1193
            E
Sbjct: 666  E 666



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 118/503 (23%), Positives = 195/503 (38%), Gaps = 57/503 (11%)

Query: 635  TFSKKPKAQYVDEGSDILLECR-LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
            +F    + + V +G   +L    + + P P + W  +G +I+P   I++ +E+ +     
Sbjct: 192  SFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQL----- 246

Query: 694  VLKITNVKKFQEGTYTVVAVN-REGE------ASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            V+  T       G Y V AVN + GE        L I   + T E   P ++ P  +  V
Sbjct: 247  VILATTTS--DAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSV 304

Query: 747  RQGESVILSAQVVGNPRP----TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802
              G S   + + + + RP    ++TW +N   + +    S G    +TI  P    D G 
Sbjct: 305  VAGSSE-TTLECIASARPVEDLSVTWKRNGVRITS-GLHSFG--RHLTISNPTSA-DTGP 359

Query: 803  YTLKAE---NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859
            Y  +A    ++   A  +A + + EP    AEP         I+ + + T+ +  +    
Sbjct: 360  YVCEAALPGSAFEPARATAFLFIIEPPYFTAEPE------SRISAEVEETVDIGCQAMGV 413

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P+P++ WY++   IS  +            L I  +  E DSG ++C ASN  G+     
Sbjct: 414  PLPTLQWYKDAISISRLQNPRYKVLASG-GLRIQKLRPE-DSGIFQCFASNEGGEIQ--T 469

Query: 920  RVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSHT--VSTKW-YHNKKEISGMDHRE 974
               +DV  +  V   Q+  +T   +G T IL C+ S     +  W   N    SG     
Sbjct: 470  HTYLDVTNIAPV-FTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIP 528

Query: 975  IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEK 1031
                              D G   C   + E S       T+      +   +D  V + 
Sbjct: 529  RFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKG 588

Query: 1032 DVAILEVEINSE---TADVVWERDGEIIKPKK-NKYDFEKRGHIRKLYIRNTSVHDEGEY 1087
              A L      +   +   VW++D   + P   ++   EK G    L I  T   D G+Y
Sbjct: 589  TTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDG---SLLISQTWSGDIGDY 645

Query: 1088 SCILRDE----SCTAEVTVVELP 1106
            SC +  E    S  A + V+ELP
Sbjct: 646  SCEIVSEGGNDSRMARLEVIELP 668



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 50/216 (23%), Positives = 96/216 (44%), Gaps = 11/216 (5%)

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX---XXARIQKLSINTTYQF 1837
            + +V ++W     +G SPI+ Y VE+ +    WK              +  L+   TYQF
Sbjct: 683  SHAVVLSWV-RPFDGNSPILYYIVELSENSSPWKVHLSNVGPEMTGVTVSGLTPARTYQF 741

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW-TEPESNGGSP 1896
            R+ A NE+G    Y+++    +     P + P+N V S  T++S+ ++W   PE+     
Sbjct: 742  RVCAVNEVGRG-QYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGV 800

Query: 1897 ITNYIIEFKT--VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954
            +  YI+ ++   + G+   + +T    V+   + ++    +   +++A N  G  L   S
Sbjct: 801  LRGYILRYRLAGLPGEYQQRNIT-SPEVNYCLVTDLIIWTQYEIQVAAYN--GAGLGVFS 857

Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
            ++V       VP+ P   ++   V S  +   W  P
Sbjct: 858  RAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPP 893



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 102/467 (21%), Positives = 178/467 (38%), Gaps = 44/467 (9%)

Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-------ILRDES 1095
            E   V W+R+G  I    + +        R L I N +  D G Y C             
Sbjct: 323  EDLSVTWKRNGVRITSGLHSFG-------RHLTISNPTSADTGPYVCEAALPGSAFEPAR 375

Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDG---SEIQFS 1149
             TA + ++E  P   T     +++   + T +I     G  L  ++W+KD    S +Q  
Sbjct: 376  ATAFLFIIE--PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNP 433

Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEF 1205
             +  L   G    L+I     +D+G + C    E G  +    L V   +  FT R P  
Sbjct: 434  RYKVLASGG----LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQR-PVD 488

Query: 1206 ILVPANTDAYLTVEIPDETLD-VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQ 1263
              V     A L  E+       +TW ++  ++   + +      ++   L I      D 
Sbjct: 489  TTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDA 548

Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
              YTC   + + +      +  +    IV    ++ + +G+  TL       P+ +  ++
Sbjct: 549  GNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYV 608

Query: 1323 -VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
                 +      T   +  K  SL I +  + D G Y   + +  G+      + +++ P
Sbjct: 609  WKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELP 668

Query: 1382 SPPGKPNILEIDSSS----INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TK 1435
              P   N+L   +SS    + + W  P + GNS I+YY+VE  E  +   + + N+    
Sbjct: 669  HSP--QNLLVSPNSSHSHAVVLSWVRPFD-GNSPILYYIVELSENSSPWKVHLSNVGPEM 725

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482
            T  ++  L    +Y+FR  AVNEV     S  T    + +E     P
Sbjct: 726  TGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPP 772



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 92/402 (22%), Positives = 153/402 (38%), Gaps = 30/402 (7%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDD--GGLELTKYAIEKHEPDNNRWIKVADVDRD- 1722
            P+ P   V    ++  ++   W PP      G+    Y +     D    + V  +  D 
Sbjct: 869  PTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN-QGYKLLAWPADAPEAVTVVTIAPDF 927

Query: 1723 --VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
              V    I  L +   Y   V+     G  +   S P ++ T  D P           +D
Sbjct: 928  HGVHHGHITNLKKFTAYFTSVLCFTTPG--DGPPSTPQLVWTQEDKPGAVGHLSFTEILD 985

Query: 1781 NESVYITWF-PSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKLSINTTYQ 1836
              S+ ++W  P EKNG   I  Y++  +  G+   +            +IQ LS  TTY 
Sbjct: 986  T-SLKVSWQEPLEKNG--IITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYT 1042

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
              + A   +GT L  +S   I+ G     P  P N V+S  + RS TL++  P  +G + 
Sbjct: 1043 IDVAAVTAVGTGLVTSST--ISSGVPPDLPGAPSNLVISNISPRSATLQF-RPGYDGKTS 1099

Query: 1897 ITNYIIEFKT---VKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLP 1951
            I+ +I+E +       + W  +           +E  N+       FR+   N VG S  
Sbjct: 1100 ISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPY 1159

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW---GTPEWDGGAPLLGYNIAI--R 2006
            + S  V     A     PT+ + +R      +   W      +++G    +GY I     
Sbjct: 1160 SPSSRVIQTLQAPPDVAPTS-VTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRS 1218

Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            D+  +   +V   D    +F I +L E   Y +++ A N +G
Sbjct: 1219 DLQSSAVAQVVS-DRLEREFTIEELEEWMEYELQMQAFNAVG 1259



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 30/94 (31%), Positives = 45/94 (47%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           ++AP+F ++       DG T    C+V G P+P ITW R+  I+         +      
Sbjct: 477 NIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG 536

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            L I  VF +DAG +TC A N  G  +++  L V
Sbjct: 537 GLQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 81/344 (23%), Positives = 133/344 (38%), Gaps = 30/344 (8%)

Query: 1725 TYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783
            T C +  L +   Y   + A N +G S A  S P+ +      P+          +    
Sbjct: 1660 TMCELTHLKKYRRYEVIMTAYNIIGESPA--SAPVEVFVGEAAPAMAPQNVQVTPLTASQ 1717

Query: 1784 VYITWFP---SEKNG---GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
            + +TW P     +NG   G  I  ++ + + E +K K          R++ L+ +T Y  
Sbjct: 1718 LEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPV-VRLKNLTSHTKYLV 1776

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
             I A N  G   P +   +   G+T    P  P     SE TS ++ + W EP +  G  
Sbjct: 1777 SISAFNAAGDG-PKSDPQQ---GRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGI- 1831

Query: 1897 ITNYIIEFK---TVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAEN-TVGVSLP 1951
            +  Y + ++    V+G S    V V G+      + ++ +     FR+ A   T G  L 
Sbjct: 1832 LQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQ 1891

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
                +   E        P +P ++ +  S   +T   T    G  P  GY I  R   + 
Sbjct: 1892 ANITAGPAE------GSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEG 1945

Query: 2012 MW-MEVGKV--DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            +W M V  +     +   ++  L +  TY  R+ A NE G  EP
Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEP 1989



 Score = 53.2 bits (122), Expect = 8e-05
 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 10/199 (5%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYENRXXXXXXXXXX 1542
            +P   I+ E  E +++ C   GVP P + WY+D     +L+  +                
Sbjct: 391  EPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRP 450

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                 ++C A N+ GE++T   + +    PV T     +      G   ++   + G P 
Sbjct: 451  EDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFT--QRPVDTTVTDGMTAILRCEVSGAPK 508

Query: 1602 PEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            P + W +  + L +           ++  ++I  +    +  YT  A+NT G+ +   TL
Sbjct: 509  PAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATL 568

Query: 1661 KVYDKPS---KPEGPVIMR 1676
             V+++ S    PE  V+++
Sbjct: 569  TVWNRTSIVHPPEDHVVIK 587



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 10/137 (7%)

Query: 1355 AGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNIL-----EIDSSSINICWDEPENTG 1408
            A I++L  +   G  + +E  V   +K   P  P  L     E+ + S+ + W  P + G
Sbjct: 1447 AYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW-VPGSDG 1505

Query: 1409 NSTIIYYVVEYQEIDTTEWISVKN-ITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDAS 1465
             S I Y+ ++ +E+   EW +  + I+   T+  +  L+  +SY+ R  A N++  SD S
Sbjct: 1506 ASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFS 1565

Query: 1466 ETTEYYKVIKETKIQSP 1482
              TE    +++   + P
Sbjct: 1566 SETEAVTTLQDVPGEPP 1582



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 5/126 (3%)

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK 1688
            +++++L +  +  + ++A        ++  +        P  P  ++   S   +T++W 
Sbjct: 1864 LKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWT 1923

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQ--KLNENCEYMFRVIAQN 1745
                 G    T Y IE    D   W + V D+ R   +Y +   KL +   Y FRV+A N
Sbjct: 1924 EG-HSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVN 1982

Query: 1746 PVGFSE 1751
              G+ E
Sbjct: 1983 EAGYGE 1988



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 8/103 (7%)

Query: 1370 DVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
            +++ N+T       PG P   ++   +S + + W E  ++G++    YV+E +  D   W
Sbjct: 1889 ELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEG-HSGDTPTTGYVIEARPSDEGLW 1947

Query: 1428 -ISVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDAS 1465
             + VK+I ++ TS    +  L+   +Y FR  AVNE    + S
Sbjct: 1948 DMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPS 1990



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 2/75 (2%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           TV   CQ  G P P + W++    I   Q+ +  Y       L I+++ PED+G F C A
Sbjct: 403 TVDIGCQAMGVPLPTLQWYKDAISISRLQNPR--YKVLASGGLRIQKLRPEDSGIFQCFA 460

Query: 586 KNAAGFASSTTELIV 600
            N  G   + T L V
Sbjct: 461 SNEGGEIQTHTYLDV 475



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%)

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012
            +S+  RLE      SP    +      S+ V+ SW  P +DG +P+L Y + + + +   
Sbjct: 656  DSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRP-FDGNSPILYYIVELSENSSPW 714

Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
             + +  V        +  L+   TY  R+ A NE+G
Sbjct: 715  KVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVG 750



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPVI 1674
            Y+ +   + +   +  L+   S K  ++A+N  G    +S  E    + D P +P G V 
Sbjct: 1527 YSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVS 1586

Query: 1675 MREISRESVTIEWKPPLDD 1693
                +  SV I+W+PP D+
Sbjct: 1587 ATPHTTSSVLIQWQPPRDE 1605


>UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin
           precursor; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Neogenin precursor - Apis mellifera
          Length = 1492

 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 88/326 (26%), Positives = 146/326 (44%), Gaps = 26/326 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F K+P+   V  G    L C L+A     I    K E       + ++++S M +  S
Sbjct: 124 PGFEKEPQDTMVYPGQIAYLSCTLLATSSSLIIQWLKDEH-----PLIISMDSRMTILPS 178

Query: 694 -VLKITNVKKFQEGTYTVVAVNR-----EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
             L+I NVK    G+Y   A +        +A L ++  I      P  + +PL+ +I+ 
Sbjct: 179 GALEIDNVKTEDVGSYRCNASSYGQYRLSNKAQLGLLSDIDQESTPPVFIAKPLQQVII- 237

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTL 805
           +G ++ L     G P+P+I W K+   +     KS     + + L    V+  D G Y  
Sbjct: 238 EGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQC 297

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +AEN   I + +A + V+ P       P FI + ++    E   ++    +   P P IT
Sbjct: 298 RAENEVEILDATADLIVQVP-------PRFIKKPEDKIASENQDLEFECEIYGKPQPKIT 350

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W +N E I+ S    Q  +G N+ +   N    ID+G ++C+ +NSAG     AR+TI+ 
Sbjct: 351 WLKNGERITLS-AYWQIVNGYNLRI---NGLLPIDAGIFQCIGTNSAGTVQAAARLTINQ 406

Query: 926 EKVTFVKHLQKSYETEEGKTVILECQ 951
            K   + H   + +T   K ++L  Q
Sbjct: 407 PKKA-ISHKSTTPKTVPKKKLLLHRQ 431



 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 156/727 (21%), Positives = 270/727 (37%), Gaps = 59/727 (8%)

Query: 1342 SASLTIKKVENTDAGIYKLRLENN-----CGHADVEMNVTILDKPSPP---GKPNILEID 1393
            S +L I  V+  D G Y+    +         A + +   I  + +PP    KP + ++ 
Sbjct: 178  SGALEIDNVKTEDVGSYRCNASSYGQYRLSNKAQLGLLSDIDQESTPPVFIAKP-LQQVI 236

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFR 1452
                 I  +   N      I ++ +   ID T + S    I  +   I N++   +  ++
Sbjct: 237  IEGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQ 296

Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512
              A NEV+I DA  T +        ++    ++KP   I +E N+D+E  C   G PQPK
Sbjct: 297  CRAENEVEILDA--TADLI-----VQVPPRFIKKPEDKIASE-NQDLEFECEIYGKPQPK 348

Query: 1513 VTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
            +TW ++G+++ T  A ++  N                ++CI  N  G V+ +  + I Q 
Sbjct: 349  ITWLKNGERI-TLSAYWQIVNGYNLRINGLLPIDAGIFQCIGTNSAGTVQAAARLTINQ- 406

Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIP---PPEVIWYKNGNKLENDKEYNITTKEKT 1627
            P   IS++    K     + L+   +       P  ++ +       N       + +  
Sbjct: 407  PKKAISHKSTTPKTVPKKKLLLHRQLYNKTWQHPSTLLGHTMSAFTPNPPLSISPSDDPA 466

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
             +        SH    +    +T    S+E ++     PS P   + +  ++   VT+ W
Sbjct: 467  DLPGSVRFPNSHYDPKSPFIDDTDSLESIEGSV-----PSAPRN-LSLVIVTARFVTLRW 520

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747
            + P +  G  L  Y   K E       +V +  + +E   I+ L  +  Y FRV+A N  
Sbjct: 521  QEPENTNGEILNYYIYYKQEGAQRE--RVINTQQKLEA-VIRGLQPSMTYHFRVVALNER 577

Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807
            G   + E   +   T  +VP             + S+ ++W   E  G +       EI 
Sbjct: 578  GSGISSEILQVTTLTEANVPGPPLNLEGYAT-SSVSIALSW--EEPQGDNE------EIT 628

Query: 1808 QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
            +E                +  L   T Y  ++ A NE G  +   S D +    +  P  
Sbjct: 629  RE---------TTSTMHDLIDLVPYTEYSIKVQAVNENGPGV--FSRDIVVRTYSAQPTQ 677

Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
             P N  V   +  S+ ++W  P       IT Y I ++     S    +   G+     +
Sbjct: 678  PPHNVTVEPVSPTSIMIRWEPPLEGQNGIITGYKIRYRRHDRASPPVNIATEGNQRSRVL 737

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMT 1985
              +++      RI A N  G    TE  Q    E  +     P  P  +R  V S+ +  
Sbjct: 738  TGLEKHVVYQVRICALNVNGTGPWTEWIQIETYETESDENRVPNTPSNLRTKVMSDYIQV 797

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045
             W  P+ D    + GY +          +EV  +D     F I  L     Y+I + A N
Sbjct: 798  FWNPPK-DQSIKVKGYKLGWGKGVPD--VEVRLLDGKERSFTIDQLEPITEYVISLRATN 854

Query: 2046 EIGLSEP 2052
            + G  +P
Sbjct: 855  DAGDGQP 861



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 13/198 (6%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           E  PP F  KP  Q + EGS I LEC     P+P I WL  G  I    +++        
Sbjct: 221 ESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAI----DLTSFKSRYSR 276

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747
           +  S L I+NV++   G+Y   A N     +A+  +++++      PP+ I+  +  I  
Sbjct: 277 IAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQV------PPRFIKKPEDKIAS 330

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           + + +    ++ G P+P ITW KN + +         + +++ I     + D G++    
Sbjct: 331 ENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQIVNGYNLRINGLLPI-DAGIFQCIG 389

Query: 808 ENSEGIAETSAVITVEEP 825
            NS G  + +A +T+ +P
Sbjct: 390 TNSAGTVQAAARLTINQP 407



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 1/100 (1%)

Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563
           +++S  P+F+ K   +   +GST+  EC   GYP+P I W +    I  +  F+  Y   
Sbjct: 219 DQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLT-SFKSRYSRI 277

Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
             ++LVI  V   D G++ C A+N      +T +LIV+ P
Sbjct: 278 AASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVP 317



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F++K   K   +   ++FEC++ G P+P+ITW +    I  S     Y+   N   L 
Sbjct: 318 PRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERITLS----AYWQIVNGYNLR 373

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           I  + P DAG F C+  N+AG   +   L +  P
Sbjct: 374 INGLLPIDAGIFQCIGTNSAGTVQAAARLTINQP 407



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 95/440 (21%), Positives = 172/440 (39%), Gaps = 27/440 (6%)

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697
            +S K      N  G  S ++ ++ Y  +P++P   V +  +S  S+ I W+PPL+     
Sbjct: 647  YSIKVQAVNENGPGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRWEPPLEGQNGI 706

Query: 1698 LTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEAL 1753
            +T Y I     D  +  + +A  + +  +  +  L ++  Y  R+ A N  G   ++E +
Sbjct: 707  ITGYKIRYRRHDRASPPVNIA-TEGNQRSRVLTGLEKHVVYQVRICALNVNGTGPWTEWI 765

Query: 1754 ESEPIVIKTALD-VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812
            + E    ++  + VP+           D   V+  W P  K+    +  YK+   +    
Sbjct: 766  QIETYETESDENRVPNTPSNLRTKVMSDYIQVF--WNPP-KDQSIKVKGYKLGWGKGVPD 822

Query: 1813 WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT---IGKTLTPPSQ 1868
             +         +  I +L   T Y   + A N+ G   P  ++ + T   + +   P   
Sbjct: 823  VEVRLLDGKERSFTIDQLEPITEYVISLRATNDAGDGQPAYANVRTTERSVSEFSAPLLP 882

Query: 1869 PRNFVVSESTSRSVTLKWTE---PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P     S  +  +V L WT+   P++   +    Y++ + T    S         +   +
Sbjct: 883  PVGLKASVLSDTTVVLYWTDTTLPKTQFVTDNRYYVVRY-TSHHHSSNPRYKYHNATDLN 941

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IV 1983
            C+ N   K   ++  + +   G      S  V  +     PS     L I+ +      V
Sbjct: 942  CMIN-DLKPNTLYEFTVKLVKGKRESLWSMVVSNQTQEAAPSSAPRNLTIQSIEDRPTSV 1000

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIR-DVTK--TMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040
            +  W  P+   G P+ GY I    D TK    W+  G +   T +F ++ L  + TY  +
Sbjct: 1001 LLRWQPPKQPNG-PITGYIIFYSIDNTKWDRDWLIEGVIGDKT-EFIVKGLQPSMTYYFK 1058

Query: 2041 IYARNEIGLSEPLESDEPFK 2060
            I ARN  G   P  +  PFK
Sbjct: 1059 IQARNSKGYG-PFSTTYPFK 1077



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 20/49 (40%), Positives = 28/49 (57%)

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
           AD++  +PP F KKP+ +   E  D+  EC +   P+P I WL  GE I
Sbjct: 310 ADLIVQVPPRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERI 358



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 75/377 (19%), Positives = 140/377 (37%), Gaps = 27/377 (7%)

Query: 1024 QDFEVKEKDVAILEVEINSETA--DVVWERD-GEIIKPKKNKYDFE-KRGHIRKLYIRNT 1079
            QD  V++ + A L+ E NS     ++ W  D G+ I    + Y  +   G +    +  T
Sbjct: 32   QDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLYINSVYGT 91

Query: 1080 SVHDEGEYSCILRDESCTA---EVTVVELP--PEIITRLQNQKVNKGNKATFEIEL--TK 1132
            S+   G Y C+   +   A    +  +++   P      Q+  V  G  A     L  T 
Sbjct: 92   SLELTGSYQCLASVDDIGAIVSRIATIKIASLPGFEKEPQDTMVYPGQIAYLSCTLLATS 151

Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE--------VGNSK 1184
               +++W KD   +  S   ++TI      L+I +   +D G Y C         + N  
Sbjct: 152  SSLIIQWLKDEHPLIISMDSRMTIL-PSGALEIDNVKTEDVGSYRCNASSYGQYRLSNKA 210

Query: 1185 CTAILT-VEEPSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241
               +L+ +++ S    F  +  + +++  +T              + W K    I+ T  
Sbjct: 211  QLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLTSF 270

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIK 1300
             +  S +   +L+I    E D   Y C   +         + +V+ PP+ +    +    
Sbjct: 271  KSRYSRIAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVPPRFIKKPEDKIAS 330

Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360
               D+    +    PQP   W+ N + I    + +        +L I  +   DAGI++ 
Sbjct: 331  ENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQ---IVNGYNLRINGLLPIDAGIFQC 387

Query: 1361 RLENNCGHADVEMNVTI 1377
               N+ G       +TI
Sbjct: 388  IGTNSAGTVQAAARLTI 404



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 55/262 (20%), Positives = 98/262 (37%), Gaps = 17/262 (6%)

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            EY  +V A N  G    + S  IV++T    P+          +   S+ I W P  +  
Sbjct: 646  EYSIKVQAVNENG--PGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRWEPPLEGQ 703

Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYT 1852
               I  YK+  ++  +             R   +  L  +  YQ RI A N  GT  P+T
Sbjct: 704  NGIITGYKIRYRRHDRASPPVNIATEGNQRSRVLTGLEKHVVYQVRICALNVNGTG-PWT 762

Query: 1853 SDDKITIGKTLTP----PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908
               +I   +T +     P+ P N + ++  S  + + W  P+      +  Y + +   K
Sbjct: 763  EWIQIETYETESDENRVPNTPSN-LRTKVMSDYIQVFWNPPKDQ-SIKVKGYKLGWG--K 818

Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
            G    ++  + G      I+ ++   E +  + A N  G   P  +     E+  +  S 
Sbjct: 819  GVPDVEVRLLDGKERSFTIDQLEPITEYVISLRATNDAGDGQPAYANVRTTERSVSEFSA 878

Query: 1969 PTAP---LEIRMVGSNIVMTSW 1987
            P  P   L+  ++    V+  W
Sbjct: 879  PLLPPVGLKASVLSDTTVVLYW 900


>UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23;
           Euteleostomi|Rep: Roundabout homolog 3 precursor - Homo
           sapiens (Human)
          Length = 1386

 Score = 97.1 bits (231), Expect = 5e-18
 Identities = 81/319 (25%), Positives = 134/319 (42%), Gaps = 23/319 (7%)

Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664
           SD G  + V            A+++    P+F ++P  Q V   + +   C +   P P 
Sbjct: 229 SDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPR 288

Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
           + W  +  E+         I SD  ++     I +V    EGTYT VA N  G A     
Sbjct: 289 LRWRKEDGELPTGR---YEIRSDHSLW-----IGHVSAEDEGTYTCVAENSVGRAEASGS 340

Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784
           L +      PPQ++   +  +   GESV    +  GNP P I W K    V   P++S  
Sbjct: 341 LSVHV----PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQ 396

Query: 785 DTHSITILKPKKVK-------DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837
            T   ++    ++        D G Y  +A +  G     A++ ++  + +   PP+ + 
Sbjct: 397 PTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGL-PPVILQ 455

Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897
                T+    ++ L  RVT NP PS+ W ++ + +   +   +     N  L I NV  
Sbjct: 456 GPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTM--ANGTLYIANV-Q 512

Query: 898 EIDSGDYKCVASNSAGKSS 916
           E+D G Y CVA +S G+++
Sbjct: 513 EMDMGFYSCVAKSSTGEAT 531



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 116/487 (23%), Positives = 201/487 (41%), Gaps = 65/487 (13%)

Query: 833  PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL-- 890
            P  + +  ++ V       L  R    P P+I WY+N   ++   T+ ++     + L  
Sbjct: 64   PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVA---TVREDPRAHRLLLPS 120

Query: 891  -------VITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEE 942
                   ++    +  D G Y CVA N  G + S  A + + V +  F +    +     
Sbjct: 121  GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDF-RQSPGNVVVAV 179

Query: 943  GKTVILEC--QTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            G+  +LEC     H   S  W  +   +   + R  I+ G+            D G+  C
Sbjct: 180  GEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKS---DAGMYVC 236

Query: 1000 IVK----DQETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWER-DG 1053
            +      ++E++   V+    P F+R+ +    + +  V  L          + W + DG
Sbjct: 237  VASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDG 296

Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEII 1110
            E+      +Y+  +  H   L+I + S  DEG Y+C+  +    AE +    V +PP+++
Sbjct: 297  EL---PTGRYEI-RSDH--SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLV 350

Query: 1111 TRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGK-----KQKL 1163
            T+ Q+Q    G    F+ E TKG+    + W K+GS++       L   G+     + +L
Sbjct: 351  TQPQDQMAAPGESVAFQCE-TKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQL 409

Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL-- 1216
             I      DAG Y C+     G+    A+L ++  S++    LP  IL  PAN    L  
Sbjct: 410  NITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLD---GLPPVILQGPANQTLVLGS 466

Query: 1217 TVEIP-----DETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
            +V +P     +    V W K    ++ D  +F  +++    TL I    E D   Y+CV 
Sbjct: 467  SVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMAN---GTLYIANVQEMDMGFYSCV- 522

Query: 1271 LDAKSTT 1277
              AKS+T
Sbjct: 523  --AKSST 527



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 83/348 (23%), Positives = 148/348 (42%), Gaps = 48/348 (13%)

Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586
           V F C+V+G P P++ W ++   + P+  +++  D     +L I  V  ED GT+TCVA+
Sbjct: 275 VTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDH----SLWIGHVSAEDEGTYTCVAE 329

Query: 587 NAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           N+ G A ++  L V  P   ++    +M                  +G PP     P   
Sbjct: 330 NSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCET-----KGNPP-----PAIF 379

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
           +  EGS +L               LF  + + P    SV+           L IT V++ 
Sbjct: 380 WQKEGSQVL---------------LFPSQSLQPTGRFSVSPRGQ-------LNITAVQRG 417

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGN 761
             G Y   AV+  G      +L+IK    +  PP +++   +  +  G SV L  +V GN
Sbjct: 418 DAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
           P+P++ W K+ + ++    +     +    +   +  D G Y+  A++S G A  S  + 
Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537

Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
           + E    + +PP      +  +     +  +V  +T+N + ++TW  N
Sbjct: 538 MREDWGVSPDPPT-----EPSSPPGAPSQPVVTEITKNSI-TLTWKPN 579



 Score = 70.9 bits (166), Expect = 4e-10
 Identities = 114/532 (21%), Positives = 199/532 (37%), Gaps = 56/532 (10%)

Query: 1262 DQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL-LVDYQAFPQP 1317
            D+  YTCV    L A ++    +EV               +  G    L  V  +  P+P
Sbjct: 137  DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEP 196

Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVT 1376
            +  W    K   + K  +  I  +   L +     +DAG+Y     N  G  +     V 
Sbjct: 197  SVSW---RKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVM 253

Query: 1377 ILDKPSPPGKP--NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434
            +L++PS   +P   ++  D+    +C  + +       + +  E  E+ T  +  +++  
Sbjct: 254  VLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPR---LRWRKEDGELPTGRY-EIRS-- 307

Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494
                 I ++       +   A N V  ++AS +   +       +    V +P   +   
Sbjct: 308  DHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH-------VPPQLVTQPQDQMAA- 359

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKL---------KTAKATYENRXXXXXXXXXXXXX 1545
            P E +   C   G P P + W ++G ++          T + +   R             
Sbjct: 360  PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDA 419

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
              Y C A +  G +    ++ I+   +      I      Q   +G    +   + G P 
Sbjct: 420  GYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQ 479

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P V W K+G  L+ D     T    T  + I  ++      Y+  A ++ G ++    LK
Sbjct: 480  PSVRWKKDGQWLQGDDLQFKTMANGT--LYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537

Query: 1662 VY-------DKPSKPEGPV------IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708
            +        D P++P  P       ++ EI++ S+T+ WKP     G  +T Y IE   P
Sbjct: 538  MREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPN-PQTGAAVTSYVIEAFSP 596

Query: 1709 -DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758
               N W  VAD    +ET+ +  L  N  Y+F V A    G SE +  SEP+
Sbjct: 597  AAGNTWRTVAD-GVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPV 647



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 75/329 (22%), Positives = 127/329 (38%), Gaps = 24/329 (7%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV---PDENISVAIES 686
           E   P   ++P    V  G    L CR    P P+I W   G  +     D      +  
Sbjct: 60  EDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLP 119

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMI 745
              ++   +      +  EG YT VA N  G  AS    L++     +  Q   P  +++
Sbjct: 120 SGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQ--SP-GNVV 176

Query: 746 VRQGESVILS-AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
           V  GE  +L      G+P P+++W K+   +K    +       + +    K  D G+Y 
Sbjct: 177 VAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLK-SDAGMYV 235

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
             A N  G  E++A   +        E P F+ R     V     +  +  V  +P P +
Sbjct: 236 CVASNMAGERESAAAEVMV------LERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRL 289

Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            W + +      E  T  ++   +  L I +V +E D G Y CVA NS G++     +++
Sbjct: 290 RWRKED-----GELPTGRYEIRSDHSLWIGHVSAE-DEGTYTCVAENSVGRAEASGSLSV 343

Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT 952
            V      +   +      G++V  +C+T
Sbjct: 344 HVPPQLVTQ--PQDQMAAPGESVAFQCET 370



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 34/223 (15%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDFQM--YYDDDNV 565
           P  V + + +    G +V F+C+ +G P P I W ++    ++ PSQ  Q    +     
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
             L I  V   DAG + C A + AG       ++ +A L   G+                
Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAG------SILAKALLEIKGAS--------------- 445

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
              L+G+PP   + P  Q +  GS + L CR+   P+P + W   G+ +  D+   +  +
Sbjct: 446 ---LDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD---LQFK 499

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
           +   M    L I NV++   G Y+ VA +  GEA+    LK++
Sbjct: 500 T---MANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMR 539



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 9/113 (7%)

Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSV 1922
            +PP  P   VV+E T  S+TL W +P    G+ +T+Y+IE F    G +W + V  G  +
Sbjct: 554  SPPGAPSQPVVTEITKNSITLTW-KPNPQTGAAVTSYVIEAFSPAAGNTW-RTVADGVQL 611

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLE 1974
              H +  ++     +F + A    G+S P+  S+ VR     T  S P+ P+E
Sbjct: 612  ETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVR-----TQDSSPSRPVE 659


>UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14761,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 912

 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 88/299 (29%), Positives = 126/299 (42%), Gaps = 26/299 (8%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           +PP     P     +EG  I L C+   +P+PD+ W   G  +    ++   +   +H  
Sbjct: 600 VPPEIHAGPYHYIANEGVSITLFCKSSGVPKPDVVW---GGSL----SLGTMLPVSVHQM 652

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
            +   I +      G Y   + N  G AS  I L + T  +  P     LK++I   G+S
Sbjct: 653 AT-FHIPHPTTDDAGIYVCTSTNPVGYASREIQLSVNTKPRIQPAATL-LKALI---GQS 707

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           V L   V G P P +TW  N  PV         +T  + I K K + D+G Y   A NS 
Sbjct: 708 VTLPCVVQGEPSPEVTWFHNGLPVGIK------NTTPLRIQKAK-LNDQGTYKCVATNSA 760

Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
           G  ETS +          AEP    +   E     K  I   A    +P P I WYRN  
Sbjct: 761 G-QETSEIKLDILDAPSFAEPG---DALLEKVANTKVIIPCPAE--GSPRPKIRWYRNGL 814

Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            I P ++  + F  E+  L I++  S   SGD+ CVA+N AG      R+ I+ +   F
Sbjct: 815 EIHPEQSSPELFVSEDGALTISSA-SASHSGDFMCVATNEAGSVERKTRLKIEGDPPVF 872



 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 105/411 (25%), Positives = 158/411 (38%), Gaps = 37/411 (9%)

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXX 619
           DD   TL IR V   DAG +TCVA + AG A+ T  L V  E+      +E T+      
Sbjct: 438 DDYHGTLHIRGVQKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDCTQ 497

Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW-LFKGEEIVPDE 678
                  +      P FS+ P       G ++ L C     P+P ++W    G +I+   
Sbjct: 498 RRFSPLTE-----DPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGS 552

Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
              +    D H     L I  V    EG Y   A N  G       L + TG   PP++ 
Sbjct: 553 RSRMVQLEDGH-----LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSV-TG-LVPPEIH 605

Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798
                 I  +G S+ L  +  G P+P + W  +      LP  S     +  I  P    
Sbjct: 606 AGPYHYIANEGVSITLFCKSSGVPKPDVVWGGSLSLGTMLPV-SVHQMATFHIPHP-TTD 663

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
           D G+Y   + N  G A     ++V   T+   +P   +    +  + +  T+  V  V  
Sbjct: 664 DAGIYVCTSTNPVGYASREIQLSVN--TKPRIQPAATL---LKALIGQSVTLPCV--VQG 716

Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
            P P +TW+ N   +    T         +           D G YKCVA+NSAG+ +  
Sbjct: 717 EPSPEVTWFHNGLPVGIKNTTPLRIQKAKLN----------DQGTYKCVATNSAGQETSE 766

Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEI 967
            ++ I ++  +F +      E      VI+ C  + S     +WY N  EI
Sbjct: 767 IKLDI-LDAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEI 816



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 82/369 (22%), Positives = 146/369 (39%), Gaps = 38/369 (10%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEF-PPKIVDYEREYRIKRGSDVTLLV 1309
            L+I+     D+  Y C   +   T K   ++ V    PP+I      Y    G  +TL  
Sbjct: 564  LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFC 623

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
                 P+P+  W  +  +        P    + A+  I      DAGIY     N  G+A
Sbjct: 624  KSSGVPKPDVVWGGSLSLGTML----PVSVHQMATFHIPHPTTDDAGIYVCTSTNPVGYA 679

Query: 1370 DVEMNVTILDKPS-PPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
              E+ +++  KP   P    +  +   S+ + C  + E +   T  +  +          
Sbjct: 680  SREIQLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLP--------- 730

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
            + +KN T  +  IQ  K N    ++  A N    S   ET+E    IK   + +P+  +P
Sbjct: 731  VGIKNTTPLR--IQKAKLNDQGTYKCVATN----SAGQETSE----IKLDILDAPSFAEP 780

Query: 1488 LKNITTE-PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE----NRXXXXXXXXXX 1542
               +  +  N  + + C   G P+PK+ WYR+G ++   +++ E                
Sbjct: 781  GDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGALTISSASA 840

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601
                 + C+A N+ G VE    + I+   PV  I  E ++    +     +  + +G P 
Sbjct: 841  SHSGDFMCVATNEAGSVERKTRLKIEGDPPVFGIQEEKVRMNGSL----TLACMTKGFPE 896

Query: 1602 PEVIWYKNG 1610
            P++ W+K+G
Sbjct: 897  PKIQWFKDG 905



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 30/229 (13%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G  + L C +   P P++ W   G        + V I++      + L+I   K   +GT
Sbjct: 705 GQSVTLPCVVQGEPSPEVTWFHNG--------LPVGIKNT-----TPLRIQKAKLNDQGT 751

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES-VILSAQVVGNPRPTI 766
           Y  VA N  G+ +  I L I     + P   EP  +++ +   + VI+     G+PRP I
Sbjct: 752 YKCVATNSAGQETSEIKLDIL----DAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKI 807

Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            W +N     P ++ P     +  ++TI         G +   A N  G  E    + +E
Sbjct: 808 RWYRNGLEIHPEQSSPELFVSEDGALTI-SSASASHSGDFMCVATNEAGSVERKTRLKIE 866

Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
                  +PP+F    QE  V+  G++ L       P P I W+++ ++
Sbjct: 867 ------GDPPVF--GIQEEKVRMNGSLTLACMTKGFPEPKIQWFKDGQV 907



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 6/170 (3%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            + + L C+  G P P+VTW+ +G  +       +N                YKC+A N  
Sbjct: 706  QSVTLPCVVQGEPSPEVTWFHNGLPVGI-----KNTTPLRIQKAKLNDQGTYKCVATNSA 760

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616
            G+  +   + I   P      + + +K     + ++    EG P P++ WY+NG ++  +
Sbjct: 761  GQETSEIKLDILDAPSFAEPGDALLEK-VANTKVIIPCPAEGSPRPKIRWYRNGLEIHPE 819

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
            +        +   + I     SHS  +   A+N AG+   +  LK+   P
Sbjct: 820  QSSPELFVSEDGALTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDP 869



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 14/193 (7%)

Query: 1496 NEDIELT--CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            NE + +T  C   GVP+P V W            +                   Y C + 
Sbjct: 614  NEGVSITLFCKSSGVPKPDVVWGGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTST 673

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N  G       + +  KP I  +   +K    +G    +  V++G P PEV W+ NG  +
Sbjct: 674  NPVGYASREIQLSVNTKPRIQPAATLLKAL--IGQSVTLPCVVQGEPSPEVTWFHNGLPV 731

Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GP 1672
                       + T+ +RI++ K +    Y   A+N+AG  + E+ L + D PS  E G 
Sbjct: 732  GI---------KNTTPLRIQKAKLNDQGTYKCVATNSAGQETSEIKLDILDAPSFAEPGD 782

Query: 1673 VIMREISRESVTI 1685
             ++ +++   V I
Sbjct: 783  ALLEKVANTKVII 795



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 56/271 (20%), Positives = 100/271 (36%), Gaps = 15/271 (5%)

Query: 1420 QEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
            Q++D  ++  V +    T T   +LK      F+ +       SD   T   +  + E  
Sbjct: 450  QKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDC--TQRRFSPLTEDP 507

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKT---AKATYENRXX 1534
            + S T    +  I     E++ L C   G PQP V+W+R DG+++ T   ++        
Sbjct: 508  LFSETPADLMAKI----GENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGH 563

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y C A N  G ++T   + +       I           G    +  
Sbjct: 564  LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFC 623

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
               G+P P+V+W   G  L       ++   + +   I       +  Y   ++N  G +
Sbjct: 624  KSSGVPKPDVVW---GGSLSLGTMLPVSV-HQMATFHIPHPTTDDAGIYVCTSTNPVGYA 679

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685
            S E+ L V  KP       +++ +  +SVT+
Sbjct: 680  SREIQLSVNTKPRIQPAATLLKALIGQSVTL 710



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 3/72 (4%)

Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDF-QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           C  EG PRP+I W+R    I P Q   +++  +D    L I       +G F CVA N A
Sbjct: 797 CPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSED--GALTISSASASHSGDFMCVATNEA 854

Query: 590 GFASSTTELIVE 601
           G     T L +E
Sbjct: 855 GSVERKTRLKIE 866



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 62/252 (24%), Positives = 96/252 (38%), Gaps = 52/252 (20%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G +V   C V+G P P++TWF     +             N   L I++    D GT+ C
Sbjct: 705 GQSVTLPCVVQGEPSPEVTWFHNGLPV----------GIKNTTPLRIQKAKLNDQGTYKC 754

Query: 584 VAKNAAGFASSTTEL-IVEAP-LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
           VA N+AG  +S  +L I++AP  ++ G  +                ++   P   S +PK
Sbjct: 755 VATNSAGQETSEIKLDILDAPSFAEPGDAL--------LEKVANTKVIIPCPAEGSPRPK 806

Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701
            ++   G +I         PE     LF  E+                     L I++  
Sbjct: 807 IRWYRNGLEI--------HPEQSSPELFVSED-------------------GALTISSAS 839

Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
               G +  VA N  G       LKI   E +PP  +  ++   VR   S+ L+    G 
Sbjct: 840 ASHSGDFMCVATNEAGSVERKTRLKI---EGDPP--VFGIQEEKVRMNGSLTLACMTKGF 894

Query: 762 PRPTITWCKNNK 773
           P P I W K+ +
Sbjct: 895 PEPKIQWFKDGQ 906



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 5/93 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVAT 567
           P+F E         G  V   C   G P+P ++W R     I+  S+   +  +D +   
Sbjct: 507 PLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGH--- 563

Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           L+I+ V+  D G + C AKN  G   +   L V
Sbjct: 564 LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSV 596



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 77/352 (21%), Positives = 141/352 (40%), Gaps = 37/352 (10%)

Query: 1047 VVWER-DG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT----AEV 1100
            V W R DG +I+   +++    + GH   L I+   + DEG Y C  ++   T    A +
Sbjct: 538  VSWHRHDGRQILTGSRSRMVQLEDGH---LLIQGVWLSDEGLYVCEAKNPFGTIKTGARL 594

Query: 1101 TVVEL-PPEIITRLQNQKVNKGNKATFEIE---LTKGDALVRWFKDGSEIQFSNHIQLTI 1156
            +V  L PPEI     +   N+G   T   +   + K D +  W   G  +     + +++
Sbjct: 595  SVTGLVPPEIHAGPYHYIANEGVSITLFCKSSGVPKPDVV--W---GGSLSLGTMLPVSV 649

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-PEFILVPANTDAY 1215
              +     I     DDAG Y C   N    A   ++  S+N   R+ P   L+ A     
Sbjct: 650  H-QMATFHIPHPTTDDAGIYVCTSTNPVGYASREIQL-SVNTKPRIQPAATLLKALIGQS 707

Query: 1216 LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLL 1271
            +T+      + + +VTW+     +           +K  T L I+K   +DQ  Y CV  
Sbjct: 708  VTLPCVVQGEPSPEVTWFHNGLPV----------GIKNTTPLRIQKAKLNDQGTYKCVAT 757

Query: 1272 DA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329
            ++  + T+++K+++++ P      +        + V +    +  P+P   W  N   I 
Sbjct: 758  NSAGQETSEIKLDILDAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIH 817

Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              + +     S+  +LTI     + +G +     N  G  + +  + I   P
Sbjct: 818  PEQSSPELFVSEDGALTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDP 869



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 38/196 (19%), Positives = 75/196 (38%), Gaps = 15/196 (7%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196
            V WF +G  +   N   L I    QK K     L+D G Y C   NS       ++   +
Sbjct: 722  VTWFHNGLPVGIKNTTPLRI----QKAK-----LNDQGTYKCVATNSAGQETSEIKLDIL 772

Query: 1197 NF-TLRLPEFILVPANTDAYLTVEIPDETLD---VTWYKKKSVIEDTEKFTLISDVKKRT 1252
            +  +   P   L+    +  + +  P E      + WY+    I   +    +   +   
Sbjct: 773  DAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGA 832

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
            L I   +     ++ CV  +   + + K  + +E  P +   + E +++    +TL    
Sbjct: 833  LTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDPPVFGIQEE-KVRMNGSLTLACMT 891

Query: 1312 QAFPQPNDEWIVNSKI 1327
            + FP+P  +W  + ++
Sbjct: 892  KGFPEPKIQWFKDGQV 907


>UniRef50_Q1CVL1 Cluster: FG-GAP repeat/fibronectin type III domain
            protein; n=1; Myxococcus xanthus DK 1622|Rep: FG-GAP
            repeat/fibronectin type III domain protein - Myxococcus
            xanthus (strain DK 1622)
          Length = 1267

 Score = 96.7 bits (230), Expect = 6e-18
 Identities = 95/404 (23%), Positives = 156/404 (38%), Gaps = 37/404 (9%)

Query: 1665 KPSKPEGPVIMREISRES----VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
            KP +P  P   R++S  +    VT+ W  P  +GG  +T Y +     ++   ++V    
Sbjct: 64   KPPEPTAPSAPRQVSAMTDPGTVTLSWFEPAQNGGSAITGYDVGVEPLEDGIQVQVEGT- 122

Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
                T  +  L     Y F + A+N VG S     + + +    DVP+            
Sbjct: 123  ----TARVTGLRAGGTYRFTITARNAVGVSPVARVDSVNLP---DVPTAPVALGVERG-- 173

Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840
            +  V +TW     +GG  ++ Y V     G               +  L+      F ++
Sbjct: 174  DRQVRVTWNAPASDGGRSVLHYVVTAHPSGAS--VATDSPVRTTTVSGLTNGVASTFTVH 231

Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900
            A N +G   P +++    +      P  P +   S    R V++ W  PE  GG P++ Y
Sbjct: 232  AVNAVGAG-PASAESTAVV--PAAQPGTPVSVAASPGV-REVSVSWQPPEDTGGLPVSGY 287

Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960
            ++   T      T    V G   E    N+++  E  F +SA N VG    + + S R  
Sbjct: 288  VV---TASPGGTTH--QVEGLASEATFTNLQDDTEYTFTVSARNDVGQGPDSSTASAR-- 340

Query: 1961 KHATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019
             HA    PP AP  ++   G   +  +W  P  DG + L GY +  +     + +EV   
Sbjct: 341  THA----PPGAPASVQAEPGVRSLTVAWAPPVSDGRSRLTGYTVMAQ--PSGVRIEVSAD 394

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
                +   + D+       I + ARN +G S    + EP K  P
Sbjct: 395  QHGAV---LEDVPSTKAQTISVVARNAVGDSPAATAGEPVKSQP 435



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/131 (23%), Positives = 53/131 (40%), Gaps = 5/131 (3%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS--S 1396
            DS   + T+  + N  A  + +   N  G        T +   + PG P  +        
Sbjct: 209  DSPVRTTTVSGLTNGVASTFTVHAVNAVGAGPASAESTAVVPAAQPGTPVSVAASPGVRE 268

Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            +++ W  PE+TG   +  YVV      TT    V+ +  ++ +  NL+ ++ Y F   A 
Sbjct: 269  VSVSWQPPEDTGGLPVSGYVVTASPGGTTH--QVEGLA-SEATFTNLQDDTEYTFTVSAR 325

Query: 1457 NEVDISDASET 1467
            N+V     S T
Sbjct: 326  NDVGQGPDSST 336



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 1380 KPSPPGKPNILEI--DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            +P+ P  P  +    D  ++ + W EP   G S I  Y V  + ++  + I V+ +  T 
Sbjct: 67   EPTAPSAPRQVSAMTDPGTVTLSWFEPAQNGGSAITGYDVGVEPLE--DGIQVQ-VEGTT 123

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS 1462
              +  L+   +YRF   A N V +S
Sbjct: 124  ARVTGLRAGGTYRFTITARNAVGVS 148


>UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whole
            genome shotgun sequence; n=9; Euteleostomi|Rep:
            Chromosome undetermined SCAF10538, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 2293

 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 112/489 (22%), Positives = 185/489 (37%), Gaps = 41/489 (8%)

Query: 653  LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
            L C+    P P   WL     + PD      +          L I + +    GTY    
Sbjct: 287  LPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTG--------LLIESAQPGDSGTYVCEV 338

Query: 713  VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
             N  G A +   L +K   K    V+ P K +    G  V LS  V G+    ++W +N 
Sbjct: 339  WNSYGNAEVVGRLYVKQPLKA---VVSPRK-VKGSVGSKVSLSCSVSGSDEYELSWYRNG 394

Query: 773  KPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            + +      +  G      I++     D G Y   A   +  A+    + +E+ T     
Sbjct: 395  EIIYPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGT----- 449

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIEL 890
             P  ++ F E  V     + LV  V   P P  +W  +++ +I  S     +++     +
Sbjct: 450  -PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHV 508

Query: 891  V----ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            V    +T+   + D G Y+C   NSAG   H AR  I+V     V+ + K+     G+  
Sbjct: 509  VSQLNVTHTQVQ-DGGQYRCTCGNSAGVVHHQAR--INVRGRASVRAM-KNLTAIAGRDA 564

Query: 947  ILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004
             + C+       S KWY N   +   +HR+   E              D G   C V  Q
Sbjct: 565  FVHCRVIGYPYYSIKWYKNSALLP-FNHRQRAFENNGTLKLSNVQQV-DAGEYTCKVMVQ 622

Query: 1005 ET---STMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059
                 S  + V+  +P +I+  + Q F + ++      V       D+ W++DG  I P 
Sbjct: 623  PNKMDSQSVHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI-PA 681

Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQ 1116
                  +       L I N +    G Y+CI R+E+   E     +V +PP+ + + ++Q
Sbjct: 682  GLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPEDQ 741

Query: 1117 KVNKGNKAT 1125
                G   T
Sbjct: 742  DGIYGKTVT 750



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 131/595 (22%), Positives = 227/595 (38%), Gaps = 62/595 (10%)

Query: 772  NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            NK  + L T S G  + + +L    + +    T      E     SA + V +PT  NAE
Sbjct: 211  NKRQRYLIT-SAGALYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPT--NAE 267

Query: 832  PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
            P + ++ F+   V     ++L  + +  P P   W ++N  + P     Q   G  IE  
Sbjct: 268  PAI-LDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTGLLIESA 326

Query: 892  ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951
                    DSG Y C   NS G +    R+ +       V    +  +   G  V L C 
Sbjct: 327  QPG-----DSGTYVCEVWNSYGNAEVVGRLYVKQPLKAVVS--PRKVKGSVGSKVSLSCS 379

Query: 952  TSHT--VSTKWYHNKKEI--------SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
             S +      WY N + I        +G++   +I EG             D G  +C  
Sbjct: 380  VSGSDEYELSWYRNGEIIYPGNSVRFTGLNRENLIMEG---------MSKSDGGAYQCFA 430

Query: 1002 KDQETS----TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE-I 1055
            +  + S      +++++  P+ +    +  V   +   L   +  +      W  D + +
Sbjct: 431  RKGKMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPV 490

Query: 1056 IKPKKNKY-DFEK-RGH-IRKLYIRNTSVHDEGEYSCILRDESCTA--EVTVVELPPEII 1110
            IK   +    +E   GH + +L + +T V D G+Y C   + +     +  +       +
Sbjct: 491  IKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRASV 550

Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
              ++N     G  A     +       ++W+K+ + + F NH Q   +     LK+ +  
Sbjct: 551  RAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPF-NHRQRAFE-NNGTLKLSNVQ 608

Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL---TVEIP----- 1221
              DAGEY+C+V          ++  S++  +R+P +I  P     +     V IP     
Sbjct: 609  QVDAGEYTCKV----MVQPNKMDSQSVHVRVRVPPYI-QPFEFQRFTIGQRVFIPCVVMS 663

Query: 1222 -DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
             D  LD+TW K    I      T+ +     +L I   T D    YTC+  +  +  + +
Sbjct: 664  GDRPLDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQ 723

Query: 1281 VE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334
               +V  PP+ V    +     G  VTL    + +P P   W  +SK   +C HT
Sbjct: 724  SRLIVRVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVW-EHSK--GRCHHT 775



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 105/496 (21%), Positives = 182/496 (36%), Gaps = 38/496 (7%)

Query: 735  PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794
            P +++  +   V     V L  +  G P P   W K+N P++  P      T +  +++ 
Sbjct: 268  PAILDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLE--PDSRFRQTVTGLLIES 325

Query: 795  KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854
             +  D G Y  +  NS G AE    + V++P +    P       +++       + L  
Sbjct: 326  AQPGDSGTYVCEVWNSYGNAEVVGRLYVKQPLKAVVSP-------RKVKGSVGSKVSLSC 378

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914
             V+ +    ++WYRN EII P  ++   F G N E +I    S+ D G Y+C A    GK
Sbjct: 379  SVSGSDEYELSWYRNGEIIYPGNSV--RFTGLNRENLIMEGMSKSDGGAYQCFARK--GK 434

Query: 915  SSHGARVTIDVEKVTFVKHLQKSYE--TEEGKTVILECQTSHTVSTK--WYHNKKEISGM 970
             S    V + +E  T  K L    E      + V L C    T   +  W  +   +   
Sbjct: 435  MSAQDFVQVILEDGT-PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKD 493

Query: 971  DHREI----IQEGR-XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKL 1023
             H  +      EG              D G  +C   +         +  +     +R +
Sbjct: 494  SHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRASVRAM 553

Query: 1024 QDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
            ++   +  +D  +    I      + W ++  ++     +  FE  G ++   + N    
Sbjct: 554  KNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLK---LSNVQQV 610

Query: 1083 DEGEYSC---ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--V 1137
            D GEY+C   +  ++  +  V V    P  I   + Q+   G +      +  GD    +
Sbjct: 611  DAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDI 670

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
             W KDG  I     + +        L+I +   D  G Y+C   N        VE  S  
Sbjct: 671  TWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAA----AVEHQSRL 726

Query: 1198 FTLRLPEFILVPANTD 1213
                 P+F++ P + D
Sbjct: 727  IVRVPPQFVVQPEDQD 742



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 94/445 (21%), Positives = 165/445 (37%), Gaps = 50/445 (11%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V   C V G    +++W+R   II P    +  +   N   L++  +   D G + C
Sbjct: 371 GSKVSLSCSVSGSDEYELSWYRNGEIIYPGNSVR--FTGLNRENLIMEGMSKSDGGAYQC 428

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
            A+     A    ++I+E                         D    I  +FS+K    
Sbjct: 429 FARKGKMSAQDFVQVILE-------------------------DGTPKILSSFSEK---- 459

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKK 702
            V+    + L C +   P P  +W    + ++ D +  +   ES      S L +T+ + 
Sbjct: 460 VVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHTQV 519

Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
              G Y     N  G       + ++ G       +  +K++    G    +  +V+G P
Sbjct: 520 QDGGQYRCTCGNSAGVVHHQARINVR-GRAS----VRAMKNLTAIAGRDAFVHCRVIGYP 574

Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV-IT 821
             +I W KN+  +     +   + +    L   +  D G YT K        ++ +V + 
Sbjct: 575 YYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNKMDSQSVHVR 634

Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
           V  P      P +    FQ  T+ ++  I  V      P+  ITW ++   I     +T 
Sbjct: 635 VRVP------PYIQPFEFQRFTIGQRVFIPCVVMSGDRPL-DITWQKDGRPIPAGLGVTV 687

Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
           +       L I N+  +  +G+Y C+A N A    H +R+ + V     V+   +  +  
Sbjct: 688 DNIDFTSSLRINNLTPD-HNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQ--PEDQDGI 744

Query: 942 EGKTVILECQTS--HTVSTKWYHNK 964
            GKTV L C        +  W H+K
Sbjct: 745 YGKTVTLNCSAEGYPPPTIVWEHSK 769



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 91/486 (18%), Positives = 176/486 (36%), Gaps = 37/486 (7%)

Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE 1193
            RW KD S ++  +  + T+ G    L I      D+G Y CEV    GN++    L V++
Sbjct: 300  RWLKDNSPLEPDSRFRQTVTG----LLIESAQPGDSGTYVCEVWNSYGNAEVVGRLYVKQ 355

Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
            P     +  P  +     +   L+  +   +  +++WY+   +I         + + +  
Sbjct: 356  PL--KAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYRNGEIIYPGNS-VRFTGLNREN 412

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVD 1310
            LI+   ++ D   Y C     K + +  V+V+  +  PKI+    E  +     V L+ +
Sbjct: 413  LIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCN 472

Query: 1311 YQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKS----ASLTIKKVENTDAGIYKLRLENN 1365
             +  P P   W + +  +IK   H     +S      + L +   +  D G Y+    N+
Sbjct: 473  VKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNS 532

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425
             G    +  + +  + S     N+  I      +         +  +I Y   Y  I   
Sbjct: 533  AGVVHHQARINVRGRASVRAMKNLTAIAGRDAFV---------HCRVIGY--PYYSIKWY 581

Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485
            +  ++      Q + +N  T      +     E       +  +        +++ P   
Sbjct: 582  KNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNKMDSQSVHVRVRVPPYI 641

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA-KATYEN---RXXXXXXXX 1540
            +P +       + + + C+     +P  +TW +DG+ +      T +N            
Sbjct: 642  QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNL 701

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y CIA N+   VE    + ++  P   +  ED  Q    G    +    EG P
Sbjct: 702  TPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPED--QDGIYGKTVTLNCSAEGYP 759

Query: 1601 PPEVIW 1606
            PP ++W
Sbjct: 760  PPTIVW 765



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 102/479 (21%), Positives = 179/479 (37%), Gaps = 49/479 (10%)

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            VI++ N    E  +  N+T  + +  + +  L++  + +  + A  +AG       + V 
Sbjct: 1219 VIYWANLPDGELGEIRNVTAVQPS--LELDGLEKYTNYRIQVLAFTSAGDGVRSEQIYVR 1276

Query: 1664 DKPSKPEGPVIMREISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
             K   P  P  ++  +  S  V + W PPL   G+ + KY I   +  +   +   +   
Sbjct: 1277 TKEDVPGPPAGVKAAASSSSAVFVSWLPPLKLNGI-IRKYIIFCSDL-HPMVMSEFEASP 1334

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            D   Y I  L  N +Y   V+A    G      SE I ++     P+            N
Sbjct: 1335 DAHFYRIPNLAGNRQYTIWVVAVTAAGHGN--NSEKITVEPLAKAPARILTF-------N 1385

Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841
             +V   W          + D    +K                 R + +  N ++  R   
Sbjct: 1386 GTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGR-RTVHANGSFFIRTVK 1444

Query: 1842 RNEIGTSLPYTSD----DKITIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
              + G       +    D+IT+  +   PP QPR   V+++T+ S+TL W  P  NGGS 
Sbjct: 1445 AEDSGNYSCVAGNTWGGDEITLNLQVQVPPDQPR-LTVTKTTTTSITLSWI-PGDNGGSS 1502

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG-------VS 1949
            I  YI+++     + W     +  S   + +EN+K      F ++A+N VG       + 
Sbjct: 1503 IRGYILQYSEDNSEQWGSF-PISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEIIE 1561

Query: 1950 LPTESQSVRL-----------EKHATV----PSPPTAPLEIRMVGS-NIVMTSWGTPEW- 1992
              T  +  R            + H+ +    PS P    E  +  S N          W 
Sbjct: 1562 AKTHGKGNRCGHQEAGGVATRQTHSHLWRLSPSEPQFAKEHELFTSINSTRARLNLAGWN 1621

Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            +GG P+  + +  R V  + W    +  + T  + + DL E   Y +++   N  G +E
Sbjct: 1622 NGGCPITSFVLEYRAVDSSTWTSAQRTSL-TKSYVLYDLQEATWYELQMKVTNSAGSAE 1679



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 11/165 (6%)

Query: 1598 GIPPPEVIWYK---NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            G PPP V W K   NG       +   T     S   I+ +K   S  Y+  A NT G  
Sbjct: 1404 GDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFF-IRTVKAEDSGNYSCVAGNTWGGD 1462

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
             + + L+V   P +P   + + + +  S+T+ W P  D+GG  +  Y ++  E ++ +W 
Sbjct: 1463 EITLNLQVQVPPDQPR--LTVTKTTTTSITLSWIPG-DNGGSSIRGYILQYSEDNSEQWG 1519

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756
                +     +Y ++ L     Y F + AQN VG    SE +E++
Sbjct: 1520 SF-PISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEIIEAK 1563



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 50/203 (24%), Positives = 92/203 (45%), Gaps = 14/203 (6%)

Query: 1275 STTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
            ++ K+ VE + + P +I+ +          D+ L       P P  +WI  S        
Sbjct: 1365 NSEKITVEPLAKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSA---NGTP 1421

Query: 1334 TKPSIDSK-----SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
            T   +D +     + S  I+ V+  D+G Y     N  G  ++ +N+ +   P  P +  
Sbjct: 1422 TNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVAGNTWGGDEITLNLQVQVPPDQP-RLT 1480

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTN 1446
            + +  ++SI + W  P + G S+I  Y+++Y E ++ +W S   I+ ++ S  ++NLK  
Sbjct: 1481 VTKTTTTSITLSWI-PGDNGGSSIRGYILQYSEDNSEQWGSFP-ISPSERSYRLENLKCG 1538

Query: 1447 SSYRFRAYAVNEVDISDASETTE 1469
            + Y+F   A N V     SE  E
Sbjct: 1539 TWYKFTLTAQNVVGPGRISEIIE 1561



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%)

Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562
           S+  +  P  ++    +       V+  C+  GYP P+  W +  + ++P   F+     
Sbjct: 261 SDPTNAEPAILDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLEPDSRFR----- 315

Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604
             V  L+I    P D+GT+ C   N+ G A     L V+ PL
Sbjct: 316 QTVTGLLIESAQPGDSGTYVCEVWNSYGNAEVVGRLYVKQPL 357



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%)

Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913
            +D+  I  T+  P  P    + E   R++ L+WT    +G SPIT Y IE K  K  SW 
Sbjct: 946  EDRGIIQLTVQEPPDPPEVEIREVKDRTIALRWTMG-FDGNSPITGYDIECKN-KSASWL 1003

Query: 1914 KI-VT--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
               VT  V   +++  I ++        R+ A+N +G S P+   ++  ++ A  P  P 
Sbjct: 1004 SAQVTKDVSPQLNQATIIDLHPSSTYNIRMVAKNVIGNSNPSNELTITTDEAA--PDGPP 1061

Query: 1971 APLEIRMVGSNIVMTSW 1987
              + +       +  SW
Sbjct: 1062 LDVTLEPTSPQSIKVSW 1078



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 6/93 (6%)

Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM--EVGK-V 2019
            TV  PP  P +EIR V    +   W T  +DG +P+ GY+I  ++ + + W+  +V K V
Sbjct: 954  TVQEPPDPPEVEIREVKDRTIALRW-TMGFDGNSPITGYDIECKNKSAS-WLSAQVTKDV 1011

Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                 +  I DL  + TY IR+ A+N IG S P
Sbjct: 1012 SPQLNQATIIDLHPSSTYNIRMVAKNVIGNSNP 1044



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 7/204 (3%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXX 1543
            + +KN+T     D  + C   G P   + WY++   L     +  +EN            
Sbjct: 551  RAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQV 610

Query: 1544 XXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVI-EGIPP 1601
                Y C       ++++  V V ++  P I        Q+  +G    +  V+  G  P
Sbjct: 611  DAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQPFEF---QRFTIGQRVFIPCVVMSGDRP 667

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
             ++ W K+G  +       +   + TS +RI  L   H+  YT  A N A     +  L 
Sbjct: 668  LDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLI 727

Query: 1662 VYDKPSKPEGPVIMREISRESVTI 1685
            V   P     P     I  ++VT+
Sbjct: 728  VRVPPQFVVQPEDQDGIYGKTVTL 751



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 31/145 (21%), Positives = 55/145 (37%), Gaps = 3/145 (2%)

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
            +EL C   G P PK  W +D   L+      +                 Y C  +N +G 
Sbjct: 285  VELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTGLLIESAQPGDSGTYVCEVWNSYGN 344

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
             E    + ++Q     +S    K K  VG +  ++  + G    E+ WY+NG  +     
Sbjct: 345  AEVVGRLYVKQPLKAVVSPR--KVKGSVGSKVSLSCSVSGSDEYELSWYRNGEIIYPGNS 402

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKY 1643
               T   + ++I ++ + +S    Y
Sbjct: 403  VRFTGLNRENLI-MEGMSKSDGGAY 426



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 8/146 (5%)

Query: 687  DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
            D H Y    +I N+   ++ T  VVAV   G  +    + ++   K P +++    ++  
Sbjct: 1335 DAHFY----RIPNLAGNRQYTIWVVAVTAAGHGNNSEKITVEPLAKAPARILTFNGTVTT 1390

Query: 747  RQGESVILSAQVVGNPRPTITWCK---NNKPVKAL-PTKSDGDTHSITILKPKKVKDEGV 802
               + ++L  + VG+P PT+ W K   N  P   L   +     +    ++  K +D G 
Sbjct: 1391 PWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGN 1450

Query: 803  YTLKAENSEGIAETSAVITVEEPTEE 828
            Y+  A N+ G  E +  + V+ P ++
Sbjct: 1451 YSCVAGNTWGGDEITLNLQVQVPPDQ 1476



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 10/107 (9%)

Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIGTS 1848
            +G SPI  Y +E K +   W           ++ + +I     ++TY  R+ A+N IG S
Sbjct: 983  DGNSPITGYDIECKNKSASWLSAQVTKDVSPQLNQATIIDLHPSSTYNIRMVAKNVIGNS 1042

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKW-TEPESNG 1893
             P    +++TI      P  P   V  E TS +S+ + W   P   G
Sbjct: 1043 NP---SNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQG 1086



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 54/237 (22%), Positives = 98/237 (41%), Gaps = 15/237 (6%)

Query: 695  LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
            L++  ++K+      V+A    G+   S  I ++ K     PP  ++   S       S 
Sbjct: 1243 LELDGLEKYTNYRIQVLAFTSAGDGVRSEQIYVRTKEDVPGPPAGVKAAASSSSAVFVSW 1302

Query: 753  ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +   ++ G  R  I +C +  P+     ++  D H   I      +   ++ + A  + G
Sbjct: 1303 LPPLKLNGIIRKYIIFCSDLHPMVMSEFEASPDAHFYRIPNLAGNRQYTIWVV-AVTAAG 1361

Query: 813  IAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
                S  ITVE P    A+ P  I  F   +T      I L  +   +P P++ W + + 
Sbjct: 1362 HGNNSEKITVE-PL---AKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSA 1417

Query: 872  IISPSETIT--QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
              +P+  +   +     N    I  V +E DSG+Y CVA N+ G    G  +T++++
Sbjct: 1418 NGTPTNVLVDGRRTVHANGSFFIRTVKAE-DSGNYSCVAGNTWG----GDEITLNLQ 1469



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 17/185 (9%)

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403
            SL I      D+G +     N+ G     + +T+ + P PP +  I E+   +I + W  
Sbjct: 922  SLQIMPTVREDSGFFSCHAINSFGEDRGIIQLTVQEPPDPP-EVEIREVKDRTIALRWTM 980

Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITK------TQTSIQNLKTNSSYRFRAYAVN 1457
              + GNS I  Y +E +   +  W+S + +TK       Q +I +L  +S+Y  R  A N
Sbjct: 981  GFD-GNSPITGYDIECKN-KSASWLSAQ-VTKDVSPQLNQATIIDLHPSSTYNIRMVAKN 1037

Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517
             +  S+ S      ++   T   +P  + P  ++T EP     +   +   P+P+ T  +
Sbjct: 1038 VIGNSNPSN-----ELTITTDEAAP--DGPPLDVTLEPTSPQSIKVSWKVRPRPQGTCLK 1090

Query: 1518 DGKKL 1522
              + L
Sbjct: 1091 GRRAL 1095



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 650  DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709
            DI+L C+ V  P P + W+ KG       N+ V     +H   S   I  VK    G Y+
Sbjct: 1395 DIVLPCKAVGDPPPTVKWI-KGSANGTPTNVLVDGRRTVHANGSFF-IRTVKAEDSGNYS 1452

Query: 710  VVAVNREGEASLPIVLKIKTGEKEP 734
             VA N  G   + + L+++    +P
Sbjct: 1453 CVAGNTWGGDEITLNLQVQVPPDQP 1477



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 2/107 (1%)

Query: 499  EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
            EK T E  + AP  +        TP    +   C+  G P P + W + +A   P+    
Sbjct: 1367 EKITVEPLAKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLV 1426

Query: 558  MYYDDDNV-ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
                  +   +  IR V  ED+G ++CVA N  G    T  L V+ P
Sbjct: 1427 DGRRTVHANGSFFIRTVKAEDSGNYSCVAGNTWGGDEITLNLQVQVP 1473



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           P +++    +    G  V   C V    RP  ITW +    I P+       + D  ++L
Sbjct: 638 PPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI-PAGLGVTVDNIDFTSSL 696

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            I  + P+  G +TC+A+N A      + LIV  P
Sbjct: 697 RINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVP 731



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 34/177 (19%), Positives = 69/177 (38%), Gaps = 9/177 (5%)

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555
            + L+C   G  + +++WYR+G+ +    + + T  NR               Y+C A   
Sbjct: 374  VSLSCSVSGSDEYELSWYRNGEIIYPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKG 433

Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
                +    V ++      +S+   K  +     +LV  V +G PPP   W  + + +  
Sbjct: 434  KMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNV-KGTPPPRCSWSLDDDPVIK 492

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHS-----SKYTIEASNTAGTSSVEVTLKVYDKPS 1667
            D  +++   E      + +L  +H+      +Y     N+AG    +  + V  + S
Sbjct: 493  DSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRAS 549


>UniRef50_Q9N3X8 Cluster: Protein sidekick homolog precursor; n=2;
            Caenorhabditis|Rep: Protein sidekick homolog precursor -
            Caenorhabditis elegans
          Length = 2325

 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 186/914 (20%), Positives = 358/914 (39%), Gaps = 83/914 (9%)

Query: 1193 EPSINFTLRLPEFILVPANTDAYLT--VEIPDETLDVTWYKKKSVIE-DTEKFTLISDVK 1249
            EPS    ++ P+ + V + TD  +           ++ W      I+ D  K+ L +D  
Sbjct: 455  EPSQKL-IKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTND-- 511

Query: 1250 KRTLIIRKCTEDDQCEYTCVLL--DAKSTTKLKVE---VVEFPPKIVDYEREYRIKRGSD 1304
               L I    + D+ EYTC +   + K+T  ++V    ++E+ P     +++  I    +
Sbjct: 512  --GLAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDSLIEYGPA----DQKSLIGTNVE 565

Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLE 1363
             +  V  +   + + EW +N  ++    ++   I  ++  SL I++V   + G Y+ R+ 
Sbjct: 566  FSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEYRCRVT 625

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
             +    +    + I++KP+ P +       E   + + + W+E  + GN  II + +E +
Sbjct: 626  VDGREENASAMLQIIEKPAMPERVRAELHNETMPAKVRVRWNEGFD-GNEPIIKHAIEMR 684

Query: 1421 EIDTT----EWIS-VKNITKTQ------TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             +  T    +W + + NI K +      T I++L+ +S+  FR  A N+      S  + 
Sbjct: 685  TMGPTGLWSDWTTAIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSY 744

Query: 1470 YYKVIKETKIQSP-----TVEKPLKNITT--EPNEDIELTCIFGGVPQPKV------TWY 1516
               + ++    +P     +   P   +    +P E+++   + G V + ++      TW 
Sbjct: 745  SVTMPQQPPSAAPRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWN 804

Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA-FNDHGEVETSCVVGIQQKPVITI 1575
                  K A+ T  +                 + +  F++  EV TS     + +P    
Sbjct: 805  EKNLTTKDARNTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTS-----EGRPTQAP 859

Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK------NGNKLENDKEYNITTKEKTSV 1629
             N  +K  +        TA  +   P   + YK         K E  K+  +    +   
Sbjct: 860  KNVRVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLT 919

Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTIEW 1687
              + EL++      T     T G       +KV  +   PE    + + E+      I W
Sbjct: 920  TVVNELEKFGHYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITW 979

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
              PL   G+ +TKY I +H   ++  +K   +VD     + I  L  +  Y   V+A   
Sbjct: 980  NSPLKQNGI-VTKYTI-RHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTR 1037

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
             G    +E          ++P           I   +V + + P   +G + I  + VE 
Sbjct: 1038 KG-DGPVEETKFESGVPPELPGRPSMLSIGD-ISATTVQLHFTPGF-DGHTAIRQWVVEG 1094

Query: 1807 KQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
            K  +   +          AR   +  L   T YQ R+ A N  G   P  S+   +    
Sbjct: 1095 KMADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAP--SEPSRSFETL 1152

Query: 1863 LTPPSQPRNFVVSESTSR-SVTLKWTEPESN--GGSPITNYIIEFKTVKGKSWTKIVTVG 1919
             T P  P   + +E  S  S+++ WT   +    G P   Y+I ++ +  ++W ++ T  
Sbjct: 1153 QTNPDTPSQRLFAEPVSATSISVSWTPLLATHWNGQP-KGYLIVYREIDDENWKEVRTPA 1211

Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979
                EH + +++        + +EN  G SLPT+  SV+   + +VPS     + +   G
Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTD--SVKARTYESVPSGSPRNIVVTAEG 1269

Query: 1980 SNIVMTSWG-TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV-DV---NTLKFNIRDLSEN 2034
            S   +  W    E      ++GY + +    +++  +  KV D+   +TL   + DL   
Sbjct: 1270 SKAAIIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPF 1329

Query: 2035 HTYMIRIYARNEIG 2048
             +Y + + A   +G
Sbjct: 1330 TSYHVYMSAYTIVG 1343



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 103/455 (22%), Positives = 174/455 (38%), Gaps = 30/455 (6%)

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPV 1673
            E N+TTK+  + + + EL      +  + A N  G    + S+EVT     +P++    V
Sbjct: 805  EKNLTTKDARNTL-VDELITWREYEIQVAAYNKRGLGVFSESIEVTTSE-GRPTQAPKNV 862

Query: 1674 IMREISRESVTIEWKPPLDDG--GLELT-KYAIEKHEPDNNRWIK--VADVDRDVETYCI 1728
             ++ ++  +V IE+  P      G+ L  K    K EP+     K  + D DR   T  +
Sbjct: 863  RVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVV 922

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
             +L +   Y    +     G  +   S  + + T  D P           + N +V ITW
Sbjct: 923  NELEKFGHYNLTTLCFTTPG--DGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAV-ITW 979

Query: 1789 FPSEKNGGSPIIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845
                K  G  +  Y +          K K           I  L  +T Y   + A    
Sbjct: 980  NSPLKQNGI-VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRK 1038

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
            G   P   + K   G     P +P    + + ++ +V L +T P  +G + I  +++E K
Sbjct: 1039 GDG-P-VEETKFESGVPPELPGRPSMLSIGDISATTVQLHFT-PGFDGHTAIRQWVVEGK 1095

Query: 1906 TVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964
                  +  +  V         +  ++   +   R+ AEN  G   P+E  S   E   T
Sbjct: 1096 MADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAPSEP-SRSFETLQT 1154

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTP----EWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
             P  P+  L    V +  +  SW TP     W+G     GY I  R++    W EV    
Sbjct: 1155 NPDTPSQRLFAEPVSATSISVSW-TPLLATHWNGQPK--GYLIVYREIDDENWKEVRTPA 1211

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055
            + + +  + DL    +Y + +++ N  G S P +S
Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTDS 1246



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 86/394 (21%), Positives = 149/394 (37%), Gaps = 24/394 (6%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK-YAIEKHEPDNNRWIKVADVDRDVE 1724
            P  P   +    +S  S+++ W P L        K Y I   E D+  W +V        
Sbjct: 1156 PDTPSQRLFAEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSS 1215

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + +  L     Y   V ++N  GF  +L ++ +  +T   VPS            +++ 
Sbjct: 1216 EHTVTDLRPFTSYEVNVFSEN--GFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAA 1273

Query: 1785 YITWFP-SEKNGGSPIIDYKVEIKQEGKKWKXXXX-------XXXXXARIQKLSINTTYQ 1836
             I W P +E +    +I YK+ +  E +                   A++  L   T+Y 
Sbjct: 1274 IIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYH 1333

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
              + A   +G   P  S   I+       P+ P +F  S  + + V +KW  P S  G  
Sbjct: 1334 VYMSAYTIVGNG-PENS-TPISFETMEDVPAPPESFQCSYISEQEVRMKWLPPGSPNGK- 1390

Query: 1897 ITNYIIEF-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS----LP 1951
            ITNYII + K+ + +S      + G++      ++    +  F I A N+ G S      
Sbjct: 1391 ITNYIISYWKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAE 1450

Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE---WDGGAPLLGYNIAIRDV 2008
              + SVRL      P+P    L        I+      P     D  +P+    ++ +  
Sbjct: 1451 VMTSSVRLPVR-NAPAPVRDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKT 1509

Query: 2009 TKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRI 2041
             +  W+ +  K + +  +  I+ LS N  +  RI
Sbjct: 1510 NEDEWITLEKKFEYSKRRSVIKHLSPNSMFRFRI 1543



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 123/608 (20%), Positives = 219/608 (36%), Gaps = 42/608 (6%)

Query: 1486 KPLKNITTEPNED-IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXX 1543
            K  K++T     D I + C   G P P + W  +G +++T    Y+              
Sbjct: 462  KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTNDGLAIHDIRKS 521

Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
                Y C     +  V+ +  V +    +I     D K       E+      E +    
Sbjct: 522  DEGEYTCEISGSN--VKATANVQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKAS 579

Query: 1604 VIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            V WY N   L    +    I+   K S+I I+++   ++ +Y    +      +    L+
Sbjct: 580  VEWYLNDVLLPVNGNSGLRISRNRKGSLI-IRQVGPDNTGEYRCRVTVDGREENASAMLQ 638

Query: 1662 VYDKPSKPE--GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDN--NRWIK 1715
            + +KP+ PE     +  E     V + W     DG   + K+AIE     P    + W  
Sbjct: 639  IIEKPAMPERVRAELHNETMPAKVRVRWNEGF-DGNEPIIKHAIEMRTMGPTGLWSDWTT 697

Query: 1716 VAD-VDRDVETYC----IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSX 1769
              D + ++    C    I+ L  +    FRV+A N  G  + +L S  + +      PS 
Sbjct: 698  AIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQ--QPPSA 755

Query: 1770 XXXXXXXXXIDNESVYITW-FPSEKNGGSPIIDYKVEIKQEGKK---W--KXXXXXXXXX 1823
                         SV + W  P E+     ++ Y V  +  G     W  K         
Sbjct: 756  APRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWNEKNLTTKDARN 815

Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883
              + +L     Y+ ++ A N+ G  + ++   ++T  +   P   P+N  V    S +V 
Sbjct: 816  TLVDELITWREYEIQVAAYNKRGLGV-FSESIEVTTSEG-RPTQAPKNVRVKVLNSTAVA 873

Query: 1884 LKWTEPESNGGSPIT-NYIIEF---KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
            +++T PE      +   Y ++F   +  KG+ + +++          + N  EK    F 
Sbjct: 874  IEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVVNELEK----FG 929

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTA--PLEIRMVGSNIVMTSWGTPEWDGGAP 1997
                 T+  + P +     + K  T    P +   L I  V  N  + +W +P    G  
Sbjct: 930  HYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITWNSPLKQNGI- 988

Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            +  Y I     +        +VD +T  F I  L  +  Y + + A    G   P+E  +
Sbjct: 989  VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKG-DGPVEETK 1047

Query: 2058 PFKVIPGE 2065
                +P E
Sbjct: 1048 FESGVPPE 1055



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 132/654 (20%), Positives = 249/654 (38%), Gaps = 53/654 (8%)

Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            W  +S  +K    TK  +D  + + TI  ++ +      +      G   VE        
Sbjct: 997  WAASSPDVK----TKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKGDGPVEETKFESGV 1052

Query: 1381 PSP-PGKPNILEI-DSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437
            P   PG+P++L I D S+  +     P   G++ I  +VVE +  D++ +  V N++  +
Sbjct: 1053 PPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWVVEGKMADSSVFAHVFNVSAPK 1112

Query: 1438 T---SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNI 1491
                ++  L+  + Y+ R  A N       SE +  ++ + +T   +P+     +P+   
Sbjct: 1113 ARSITVTGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETL-QTNPDTPSQRLFAEPVSAT 1171

Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
            +   +    L   + G P+  +  YR+       +                     Y+  
Sbjct: 1172 SISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSSEHTVTDLRPFTSYEVN 1231

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE------VI 1605
             F+++G   +     ++ +   ++ +    +   V  E    A+I+  P  E      VI
Sbjct: 1232 VFSENGFGRSLPTDSVKARTYESVPSGS-PRNIVVTAEGSKAAIIKWNPVAELSTNGDVI 1290

Query: 1606 WYKNGNKLENDKEYNITTK------EKTSVIRIKELK-----RSHSSKYTIEASNTAGTS 1654
             YK     E +      TK      + T + ++ +L+       + S YTI  +    ++
Sbjct: 1291 GYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVYMSAYTIVGNGPENST 1350

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
             +     + D P+ PE       IS + V ++W PP    G ++T Y I   +    R +
Sbjct: 1351 PISFET-MEDVPAPPES-FQCSYISEQEVRMKWLPPGSPNG-KITNYIISYWKSHEPRSM 1407

Query: 1715 KV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773
             + A +  ++  +    LN N +Y F + A+N  G SE   +E +     L V +     
Sbjct: 1408 AIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAEVMTSSVRLPVRNAPAPV 1467

Query: 1774 XXXXXIDNES-VYITWFPS-----EKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR- 1825
                     + + I W  S      ++  SP+   +V  ++  + +W           R 
Sbjct: 1468 RDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWITLEKKFEYSKRR 1527

Query: 1826 --IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL--TPPSQPRNFVVSESTSRS 1881
              I+ LS N+ ++FRI     IG  L  +   +    +TL   P +QP +   +     S
Sbjct: 1528 SVIKHLSPNSMFRFRI---RFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNS 1584

Query: 1882 VTLKWTEP-ESNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEK 1933
            V L+W  P +S   S    Y I ++     ++W          HE   E I  K
Sbjct: 1585 VQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAIRDEHEDKEEKILAK 1638



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 11/156 (7%)

Query: 1139 WFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197
            W  +G EIQ  N    LT DG    L I+D    D GEY+CE+  S   A   V+    +
Sbjct: 492  WLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDS 547

Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTL-ISDVKKRTL 1253
                 P        T+   + E+  E +    V WY    ++       L IS  +K +L
Sbjct: 548  LIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSL 607

Query: 1254 IIRKCTEDDQCEYTC-VLLDAK-STTKLKVEVVEFP 1287
            IIR+   D+  EY C V +D +       ++++E P
Sbjct: 608  IIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEKP 643



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 8/73 (10%)

Query: 638 KKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696
           K PK   V  G+D I++EC     P P+I WL  G EI  D N+   + +D       L 
Sbjct: 462 KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTD-NVKYDLTND------GLA 514

Query: 697 ITNVKKFQEGTYT 709
           I +++K  EG YT
Sbjct: 515 IHDIRKSDEGEYT 527



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
            S   +++W  +G  I+    KYD    G    L I +    DEGEY+C +   +  A   
Sbjct: 485  SPPPNIIWLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATAN 540

Query: 1102 VVELPPEIIT-RLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTID 1157
            V      +I     +QK   G    F  E+ K     A V W+ +   +  + +  L I 
Sbjct: 541  VQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRIS 600

Query: 1158 -GKKQKLKIYDCDLDDAGEYSCEV 1180
              +K  L I     D+ GEY C V
Sbjct: 601  RNRKGSLIIRQVGPDNTGEYRCRV 624



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 47/219 (21%), Positives = 90/219 (41%), Gaps = 19/219 (8%)

Query: 729 TGEKEPPQ-VIEPLKSMIVRQG-ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786
           T E EP Q +I+  K + V  G + +++     G+P P I W  N   ++    K D   
Sbjct: 451 TSELEPSQKLIKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTN 510

Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846
             + I   +K  DEG YT +   S   A  +  +  +   E         ++   I    
Sbjct: 511 DGLAIHDIRK-SDEGEYTCEISGSNVKATANVQVNGDSLIEYGP-----ADQKSLIGTNV 564

Query: 847 KGTIKLVARVTRNPVPSITWYRNNEII----SPSETITQNFDGENIELVITNVDSEIDSG 902
           + + ++     R    S+ WY N+ ++    +    I++N  G    L+I  V  + ++G
Sbjct: 565 EFSCEVAKEYVRK--ASVEWYLNDVLLPVNGNSGLRISRNRKG---SLIIRQVGPD-NTG 618

Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941
           +Y+C  +    + +  A + I +EK    + ++     E
Sbjct: 619 EYRCRVTVDGREENASAMLQI-IEKPAMPERVRAELHNE 656



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
            T+ DKP P G     ++   S+ + WDEP    N  +I Y+V Y+     E    KN  +
Sbjct: 1769 TLEDKPGPVGILRFSDVLMDSVKVSWDEPSQP-NGNVIGYIVNYKGYRMQE--EFKNEDQ 1825

Query: 1436 TQTS 1439
             +TS
Sbjct: 1826 QRTS 1829


>UniRef50_Q13203 Cluster: Myosin-binding protein H; n=35;
            Tetrapoda|Rep: Myosin-binding protein H - Homo sapiens
            (Human)
          Length = 477

 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 68/302 (22%), Positives = 136/302 (45%), Gaps = 21/302 (6%)

Query: 1282 EVVEFPP-KIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339
            E +E P  ++  + R+  I++ G  V L + +Q  P+P   W  N   +   + +  + D
Sbjct: 167  ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
              S  L I+  + +D+G Y+L +      A   +++ +++KP PP    +L++   +  +
Sbjct: 227  QDSI-LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAAL 285

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             W  P++TGN+ ++ Y+V+  +  T +W +V +    T  +I +L   +SY FR ++ N 
Sbjct: 286  QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345

Query: 1459 VDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIELTCIF 1505
              +S ++  T+    I++  I             ++P+  +PL + T+ P    +L C  
Sbjct: 346  CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405

Query: 1506 GGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561
               P+PK+ W ++  ++    K    + +                 Y C A N  GE   
Sbjct: 406  RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465

Query: 1562 SC 1563
             C
Sbjct: 466  DC 467



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 43/167 (25%), Positives = 81/167 (48%), Gaps = 5/167 (2%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            +VG+   +    +G P P+  W  NG+ L++ +  ++ T ++ S++ I+  +RS S +Y 
Sbjct: 187  QVGETVNLQIPFQGKPKPQATWTHNGHALDSQR-VSMRTGDQDSILFIRSAQRSDSGRYE 245

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            +        +   + + V +KP  P   + + ++   +  ++W PP D G  EL  Y ++
Sbjct: 246  LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304

Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFS 1750
            K +    +W  V  ++R   T C I  L     Y FRV ++N  G S
Sbjct: 305  KADKKTGQWFTV--LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 7/155 (4%)

Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436
            D PS P    + ++ SSS+ + W+ PE  G   +  YV+E      +EW  +S + +  T
Sbjct: 69   DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LKNITT 1493
            Q +++NL     +  R  AV+       +   +   +     I++P +  P    +    
Sbjct: 129  QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI--RENIEAPKIRVPRHLRQTYIR 186

Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528
            +  E + L   F G P+P+ TW  +G  L + + +
Sbjct: 187  QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVS 221



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%)

Query: 492 IDKLPVFEKPTS---EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548
           I K  +  KP      + S AP F + L    +  G + Q  C V   P+P+I W +   
Sbjct: 361 IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM 420

Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
            I+ +  ++    +  V TL IR+  P D+G +TC A N  G AS    L V+A
Sbjct: 421 EIQGNPKYRAL-SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            PS P    + + +S SVT+ W  PE  G   +  Y++E        W  +      V + 
Sbjct: 71   PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966
             + N+   D+ + R+SA ++ G   P    Q + + ++   P
Sbjct: 131  TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 4/150 (2%)

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EI 1678
            + T E    + + E  R          +  A T+S   T         P  P+++   ++
Sbjct: 24   VPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTAST-ATKPAPPSEDVPSAPLLLTLDDV 82

Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738
            S  SVT+ W+PP   G L L  Y +E      + W+ V+     V    ++ L    +++
Sbjct: 83   SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFL 142

Query: 1739 FRVIAQNPVGFS-EALESEPIVIKTALDVP 1767
             RV A +  G    A+  +PI I+  ++ P
Sbjct: 143  LRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 65/299 (21%), Positives = 114/299 (38%), Gaps = 31/299 (10%)

Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXX 1823
            DVPS          + + SV ++W P E+ G   +  Y +E+ +EG  +W          
Sbjct: 69   DVPSAPLLLTLDD-VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127

Query: 1824 AR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--QPRNFVVSESTS 1879
             +  ++ L++   +  R+ A +  G   P   D  I I + +  P    PR+        
Sbjct: 128  TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRH-------- 179

Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-NIKEKDEIIF 1938
                L+ T     G +       + K     +WT     G ++    +     ++D I+F
Sbjct: 180  ----LRQTYIRQVGETVNLQIPFQGKPKPQATWTHN---GHALDSQRVSMRTGDQDSILF 232

Query: 1939 RISAENTVGVSLPTESQSVRLEKHATV-------PSPPTAPLEIRMVGSNIVMTSWGTPE 1991
              SA+ +         +   LE  A +       P PP++   + + G N  +  W  P+
Sbjct: 233  IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAAL-QWTPPQ 291

Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
              G   LLGY +   D     W  V +   +     I DL   ++Y  R+++ N  GLS
Sbjct: 292  DTGNTELLGYMVQKADKKTGQWFTVLE-RYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSI 789
           E P   +PL       G S  L   V  +P+P I W KN   ++  P     S+    ++
Sbjct: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439

Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
            I KP    D GVYT KA N  G A     + V+
Sbjct: 440 EIRKPSPF-DSGVYTCKAINVLGEASVDCRLEVK 472



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 7/106 (6%)

Query: 1963 ATVPSPPT-----APLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
            AT P+PP+     APL + +  V S+ V  SW  PE  G   L GY + +     + W+ 
Sbjct: 60   ATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVP 119

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061
            V    +   +  +R+L+    +++R+ A +  G   P   D+P  +
Sbjct: 120  VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 18/67 (26%), Positives = 36/67 (53%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655
            +   P P++IW KN  +++ + +Y   +++    + I++     S  YT +A N  G +S
Sbjct: 405  VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464

Query: 1656 VEVTLKV 1662
            V+  L+V
Sbjct: 465  VDCRLEV 471



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 7/99 (7%)

Query: 733 EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHS 788
           E P++  P  L+   +RQ GE+V L     G P+P  TW  N   + +   +   GD  S
Sbjct: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDS 229

Query: 789 ITILKPKKVKDEGVY--TLKAENSEGIAETSAVITVEEP 825
           I  ++  +  D G Y  T++ E+ E  A    ++ +E+P
Sbjct: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVID-ILVIEKP 267



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 6/96 (6%)

Query: 634 PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           P+F++ P A +    G    L C + A P+P I W+    EI  +       E  +   C
Sbjct: 382 PSFTQ-PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGV---C 437

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728
           + L+I     F  G YT  A+N  GEAS+   L++K
Sbjct: 438 T-LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472


>UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like
            precursor; n=6; Caenorhabditis|Rep: Tyrosine-protein
            phosphatase Lar-like precursor - Caenorhabditis elegans
          Length = 2200

 Score = 96.3 bits (229), Expect = 8e-18
 Identities = 117/527 (22%), Positives = 203/527 (38%), Gaps = 39/527 (7%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXX 1535
            P +E      + E  +   ++C   G P+ KV W RD   L      + + +T  N    
Sbjct: 151  PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCV---VGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                        Y+CIA N  G   +      V +++ P       + +    VG    +
Sbjct: 211  MIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINL 270

Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            T V  G P P V W K    + +D     T     +V+ +  ++ + +  +T  A +  G
Sbjct: 271  TCVAVGYPMPRVFWKKTDLMVLDDPS---TAPIGKNVLTLTHVESTEN--FTCVAVSALG 325

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE--LTKYAIEKHEPDN 1710
                  T+   + P  P   +++  ++ ESV I WKPP  +  +   +  Y ++  E  +
Sbjct: 326  NIEATTTVIAKELPPPPVN-IVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGRS 384

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
            +R   +  ++  +    I  L     Y F V +  PVG    LES P+  +T    P+  
Sbjct: 385  SRGKTMETLENSL---VIDGLVAFQTYEFTVRSAGPVGV--GLESLPVEAQTKPSKPATA 439

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-----IKQEGKKWK-XXXXXXXXXA 1824
                    ++ +S+ + W P E+  G  I  YKV      +    ++WK           
Sbjct: 440  PVSPQARSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMT 498

Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884
             I  L  ++ Y  R+ A+N  G S P ++   +T+      P QP    V    SR + L
Sbjct: 499  TINGLEPDSRYFVRVIAQNSEGDS-PLST--LVTVATRQGIPGQPPMLTVKALDSRRMQL 555

Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
             W +P  +  SP+  Y + + T  G+   K +T+     +H +  +       FR++A +
Sbjct: 556  TWDKPLYS--SPVVGYTVRYNTSDGE---KELTLTSPHEKHVVTGLHPDKYYYFRVAAYS 610

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991
              G    TE    +    A++P      +      S  V   W  PE
Sbjct: 611  DRGQGEFTEPMISK--TIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 36/301 (11%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           E  P     +P +  V + S I   CR    P P + W   G+ I     IS+     + 
Sbjct: 44  EDDPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISI---KSLA 100

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV----LKIKTGEKEP---PQV-IEP- 740
              S L+   V    +   TVV+ + +   + P+V    L +   +K P   PQ+ + P 
Sbjct: 101 TGLSTLRFERVS--LDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPS 158

Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP------ 794
           LKS  V QG++  +S +V G+PR  + W ++  P   L  ++DG     TI  P      
Sbjct: 159 LKS--VEQGKTAYVSCRVRGDPRAKVLWLRDLIP---LDIRADGRYSVSTIGNPGALMIQ 213

Query: 795 -KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKL 852
             + +D+G Y   A N+ G+A + A        +    PP F  + + +  V   G I L
Sbjct: 214 HAREEDQGKYECIARNTLGVAHSKAANLY---VKVRRVPPYFSYKLERQYVVGVGGNINL 270

Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
                  P+P + W + + ++    +      G+N+ L +T+V+S   + ++ CVA ++ 
Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPSTAP--IGKNV-LTLTHVES---TENFTCVAVSAL 324

Query: 913 G 913
           G
Sbjct: 325 G 325



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 206/967 (21%), Positives = 345/967 (35%), Gaps = 115/967 (11%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQL-TIDGKKQK 1162
            P  ++ R  +  V   +K +F      G+ L  V W  +G  I   N I + ++      
Sbjct: 47   PARLVVRPDSSTVVDESKISFFCR-ADGNPLPSVIWRVNGKSITDHNRISIKSLATGLST 105

Query: 1163 LKIYDCDLDD-AGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPA------N 1211
            L+     LDD A   SC   N     ++        P     +  P+  L P+       
Sbjct: 106  LRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQG 165

Query: 1212 TDAYLTVEIP-DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTC 1268
              AY++  +  D    V W +    ++     ++++ +      L+I+   E+DQ +Y C
Sbjct: 166  KTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYEC 225

Query: 1269 VLLDA-----KSTTKLKVEVVEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322
            +  +           L V+V   PP      ER+Y +  G ++ L      +P P   W 
Sbjct: 226  IARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWK 285

Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
                ++     T P    K+  LT+  VE+T+   +     +  G+ +    V   + P 
Sbjct: 286  KTDLMVLDDPSTAPI--GKNV-LTLTHVESTEN--FTCVAVSALGNIEATTTVIAKELPP 340

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            PP    +  + S S+ I W  P+   N  I  YVV Y+ +  +E  S +   KT  +++N
Sbjct: 341  PPVNIVVSSVTSESVVITWKPPKY--NEAINKYVVNYR-LKYSEGRSSRG--KTMETLEN 395

Query: 1443 -LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
             L  +    F+ Y              E   V  +TK   P    P+       N D  +
Sbjct: 396  SLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPAT-APVSPQARSLNRD-SI 453

Query: 1502 TCIFGGVPQPK--VTWYR---DGKKLKTAKATYENRXXXXXXXXXX------XXXXXYKC 1550
               +G   QP   +T Y+       + T    ++                        + 
Sbjct: 454  LVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRV 513

Query: 1551 IAFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603
            IA N  G+   S +V +        Q P++T+   D ++     D+ L ++ + G     
Sbjct: 514  IAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGY---- 569

Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-V 1662
             + Y   N  + +KE  +T+  +  V+      + +  +    +    G  +  +  K +
Sbjct: 570  TVRY---NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTI 626

Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPP-------------LDDGGLELTKYA-IEKHEP 1708
               P      V     S +SV I WK P             ++   LE +K A +E  E 
Sbjct: 627  ASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEY 686

Query: 1709 DNNRWIKVADVDR-------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761
            D +     + +DR       D  +Y +  L     Y   V A    G+    ES   V+K
Sbjct: 687  DEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGP--ESSIRVVK 744

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGG----SPIIDYKVE---IKQEGKKW 1813
            T  DVPS              SV +TW  P+  NG        +D  V    + ++G K 
Sbjct: 745  TLEDVPSAPRNFNAELT-SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKK 803

Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871
            +             +  L  NT Y FR+ A N  G          IT G    PP  P  
Sbjct: 804  RIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQG---IPPEAPE- 859

Query: 1872 FVVSESTSRS-----VTLKWTEPESN-GGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHE 1924
             +VS S  R        ++W  P+     +PI  Y +  +      S+ K  TV G+   
Sbjct: 860  -IVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIV 1983
              I  +         ++AEN  G      SQ+        V SP   P++++  V    +
Sbjct: 919  TTISGLWMGVVYDVLLAAENREG-----RSQNATETIATPVGSPDGEPIDVQYEVMKGKI 973

Query: 1984 MTSWGTP 1990
            + SW  P
Sbjct: 974  VVSWRPP 980



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 20/205 (9%)

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KTVKGKSWTKIV 1916
            I K L PP  P N VVS  TS SV + W  P+ N    I  Y++ +  K  +G+S ++  
Sbjct: 334  IAKELPPP--PVNIVVSSVTSESVVITWKPPKYN--EAINKYVVNYRLKYSEGRS-SRGK 388

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSVRLEKHATVPSPPTAPL 1973
            T+    +   I+ +       F + +   VGV   SLP E+Q+ +  K AT P  P A  
Sbjct: 389  TMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQT-KPSKPATAPVSPQA-- 445

Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF--NIRD 2030
              R +  + ++  WG  E   G  + GY +    D+  T   E  + D  + +F   I  
Sbjct: 446  --RSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTING 502

Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055
            L  +  Y +R+ A+N  G   PL +
Sbjct: 503  LEPDSRYFVRVIAQNSEG-DSPLST 526



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 100/451 (22%), Positives = 177/451 (39%), Gaps = 53/451 (11%)

Query: 1641 SKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGL 1696
            S+Y +   A N+ G S +   + V  +   P  P ++  + +    + + W  PL     
Sbjct: 507  SRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSS-- 564

Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756
             +  Y +  +  D  + + +       E + +  L+ +  Y FRV A +  G  E   +E
Sbjct: 565  PVVGYTVRYNTSDGEKELTLTSPH---EKHVVTGLHPDKYYYFRVAAYSDRGQGEF--TE 619

Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVE-IKQEGKKW- 1813
            P++ KT   +P             ++SV I W  P +K     +  Y++   + E  K  
Sbjct: 620  PMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTA 679

Query: 1814 -----KXXXXXXXXXARIQKLSI-----NTTY---QFRIYARNEI----GTSLPYTSDDK 1856
                 +         + + ++S+      T+Y       Y+  EI     T   Y  +  
Sbjct: 680  NLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESS 739

Query: 1857 ITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK----- 1910
            I + KTL   PS PRNF    +++ SV L W  P +  G+ +  Y+   + V G+     
Sbjct: 740  IRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEK 799

Query: 1911 -SWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968
             S  +IV +  S   +  ++++    E  FR++A N  G    +E +S+      T   P
Sbjct: 800  GSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIP 854

Query: 1969 PTAPLEIRMVGSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVD 2020
            P AP EI  V  +      +    W  P+      P+  YN+ +R       +++   VD
Sbjct: 855  PEAP-EIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVD 913

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
               L   I  L     Y + + A N  G S+
Sbjct: 914  GTDLSTTISGLWMGVVYDVLLAAENREGRSQ 944



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%)

Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPED 577
           K    G T    C+V G PR ++ W R    +    D +       N   L+I+    ED
Sbjct: 160 KSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREED 219

Query: 578 AGTFTCVAKNAAGFASS 594
            G + C+A+N  G A S
Sbjct: 220 QGKYECIARNTLGVAHS 236



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 100/460 (21%), Positives = 164/460 (35%), Gaps = 35/460 (7%)

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP 1672
            D+   +   + TS + + +L    S + T+ AS   G    SS+ V   + D PS P   
Sbjct: 698  DRMSVVVPSDATSYV-LSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRN- 755

Query: 1673 VIMREI-SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVE 1724
                E+ S  SV + W  P    G  L  Y     +   EP   +  K   V   D    
Sbjct: 756  -FNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKR 814

Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784
             + +  L+ N EY FR+ A N  G  E  E + I+  T    P            D   V
Sbjct: 815  YFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPV 872

Query: 1785 Y--ITW-FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQ 1836
               I W  P  K   +PI  Y + ++ +G      K K           I  L +   Y 
Sbjct: 873  VARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYD 931

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGS 1895
              + A N  G S   T      +G   +P  +P + V  E     + + W  P E     
Sbjct: 932  VLLAAENREGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNG 987

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
             IT+Y      +   +      V         E +  +   +F+++A    G+   +   
Sbjct: 988  NITSYKAILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVL 1046

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR-DVTKTMWM 2014
            ++  +  A V  P    +E     + +V   + + + D       +    R D  K   +
Sbjct: 1047 TINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQL 1106

Query: 2015 EVGKVD-VNTLKFN-IRDLSENHTYMIRIYA-RNEIGLSE 2051
             V  +D  N  +F  + DL+ +  Y   + A +N + L+E
Sbjct: 1107 PVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNE 1146



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           P F  KL  ++    G  +   C   GYP P++ W ++T +        M  DD + A +
Sbjct: 250 PYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFW-KKTDL--------MVLDDPSTAPI 300

Query: 569 ---VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
              V+     E    FTCVA +A G   +TT +I +
Sbjct: 301 GKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAK 336


>UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 381

 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 80/330 (24%), Positives = 152/330 (46%), Gaps = 27/330 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P+ S +P+   V  G  +  +CR+ +  +P +    K       +N+ +  +       +
Sbjct: 22  PSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPLGDNVKIGPDG------A 75

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESV 752
           VL I NV+   +G Y  +A N +G++++   L +K     PP+V + P   + +R GE V
Sbjct: 76  VLTIANVRLNNQGGYRCIATNAQGKSTVTANLSVK----HPPKVRVSPAGPLTLRVGEIV 131

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            L   V G PRP+++W +     +     +  D+ +   +     ++ G+Y  +A+N EG
Sbjct: 132 TLDCSVSGKPRPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGEG 191

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
           +AE      VE   E  A P   ++   E+T  E  ++ +  + + +P   ++W   +++
Sbjct: 192 LAEGE----VELVMEGGAFPQASVSE-TELTAVEGQSVSMHCQASGSPAAVLSW---SKL 243

Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932
            +P        DG    L ++NV  + DSG Y C A+++ G S   A V ++V+   +  
Sbjct: 244 RAPLPW-QHKVDGGT--LTLSNVGRQ-DSGQYICNATSALGFSE--AYVQLEVDSPPYAT 297

Query: 933 HLQKSYETEEGKTVILEC--QTSHTVSTKW 960
            L +      G  + L+C    SH +  +W
Sbjct: 298 VLTEVVVLRVGDALRLQCLAHGSHPIRFRW 327



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 69/278 (24%), Positives = 114/278 (41%), Gaps = 28/278 (10%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G  + L+C +   P P ++W+ + +     E +S   +S      + L++T       G 
Sbjct: 128 GEIVTLDCSVSGKPRPSVSWI-RRQAGGETELVSTTTDST-----TSLQVTMATAENAGM 181

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           Y   A N EG A   + L ++ G      V E   + +  +G+SV +  Q  G+P   ++
Sbjct: 182 YVCRAQNGEGLAEGEVELVMEGGAFPQASVSETELTAV--EGQSVSMHCQASGSPAAVLS 239

Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
           W K   P   LP +   D  ++T+    + +D G Y   A ++ G +E    + V+ P  
Sbjct: 240 WSKLRAP---LPWQHKVDGGTLTLSNVGR-QDSGQYICNATSALGFSEAYVQLEVDSPP- 294

Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYR-NNEIISPSETITQNFDG 885
                  +     E+ V   G    +  +     P    W R     +S     T+  DG
Sbjct: 295 -------YATVLTEVVVLRVGDALRLQCLAHGSHPIRFRWMRVGGACMSTGAESTK--DG 345

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
               L I  + S  DSG YKC A+N  G S   +RVT+
Sbjct: 346 L---LRIPQLKSS-DSGTYKCTATNHVGSSEALSRVTV 379



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V  +C V G PRP ++W R+ A     +   +    D+  +L +     E+AG + C
Sbjct: 128 GEIVTLDCSVSGKPRPSVSWIRRQA---GGETELVSTTTDSTTSLQVTMATAENAGMYVC 184

Query: 584 VAKNAAGFASSTTELIVE 601
            A+N  G A    EL++E
Sbjct: 185 RAQNGEGLAEGEVELVME 202



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 7/81 (8%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
           +G +V   CQ  G P   ++W +  A +     +Q   D     TL +  V  +D+G + 
Sbjct: 220 EGQSVSMHCQASGSPAAVLSWSKLRAPLP----WQHKVDG---GTLTLSNVGRQDSGQYI 272

Query: 583 CVAKNAAGFASSTTELIVEAP 603
           C A +A GF+ +  +L V++P
Sbjct: 273 CNATSALGFSEAYVQLEVDSP 293



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 50/232 (21%), Positives = 81/232 (34%), Gaps = 19/232 (8%)

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            +I N++ N+   +R  A N       S  T    V    K++      P   +T    E 
Sbjct: 78   TIANVRLNNQGGYRCIATNA---QGKSTVTANLSVKHPPKVRV----SPAGPLTLRVGEI 130

Query: 1499 IELTCIFGGVPQPKVTWYR--DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            + L C   G P+P V+W R   G + +    T ++                Y C A N  
Sbjct: 131  VTLDCSVSGKPRPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGE 190

Query: 1557 G--EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            G  E E   V+     P  ++S  ++      G    +     G P   + W    +KL 
Sbjct: 191  GLAEGEVELVMEGGAFPQASVSETELTAVE--GQSVSMHCQASGSPAAVLSW----SKLR 244

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666
                +    K     + +  + R  S +Y   A++  G S   V L+V   P
Sbjct: 245  APLPWQ--HKVDGGTLTLSNVGRQDSGQYICNATSALGFSEAYVQLEVDSPP 294



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 4/127 (3%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYEREYRIKRGSDVTLLVD 1310
            L I     ++Q  Y C+  +A+  + +   + V+ PPK+ V       ++ G  VTL   
Sbjct: 77   LTIANVRLNNQGGYRCIATNAQGKSTVTANLSVKHPPKVRVSPAGPLTLRVGEIVTLDCS 136

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
                P+P+  WI   +   + +    + DS + SL +      +AG+Y  R +N  G A+
Sbjct: 137  VSGKPRPSVSWI-RRQAGGETELVSTTTDS-TTSLQVTMATAENAGMYVCRAQNGEGLAE 194

Query: 1371 VEMNVTI 1377
             E+ + +
Sbjct: 195  GEVELVM 201


>UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9;
            Cyprinidae|Rep: Neural cell adhesion molecule L1.1 -
            Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1197

 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 158/779 (20%), Positives = 289/779 (37%), Gaps = 47/779 (6%)

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
            Y + RG  +TL    +  P P   W      +     TK   +++   L I  V  +D G
Sbjct: 187  YLVLRGQTLTLQCIPEGLPTPEVHWDRIDSALSP-NRTKKLYNNRW--LQIDNVLESDDG 243

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             Y     N+         VT+   P     P    + +    +  D   +   +  I + 
Sbjct: 244  EYVCTARNSENSVKHHYTVTVEAAPYWTRSPEE-HLYAPGETVRLDCKADGIPAPNITWS 302

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            +    +  T+    + ++  +  + N++ + +  ++  AVN+      S     +  + E
Sbjct: 303  INGVPVSGTDVDPRRRVSSGKLILSNVEFSDTAVYQCEAVNK----HGSILINTHVHVVE 358

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDG-KKLKTAKATYENRXX 1534
               Q  T ++ L   T    + + L C   G P PK+ W   D    L  AK +      
Sbjct: 359  LPAQILTPDERLYQATA--GQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGS 416

Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594
                         Y C     +  +     V  + K V    N  + +          T 
Sbjct: 417  LKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYT- 475

Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            V   +  P V W K+G+K+      N    E    +++ +++      Y+ E S T  + 
Sbjct: 476  VDHNLKSPTVQWNKDGHKITASTS-NDKYHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSD 534

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE---PDNN 1711
            +    + V DKP  P+   +  ++ R SVTI W P +++    +T+Y IE +E   PD  
Sbjct: 535  TASGYITVQDKPDPPQSLKLSEKMER-SVTISWMPSVENNS-PVTEYVIEMNEGETPDEG 592

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
            +W K   V +D++++  + +    +Y F++ A N +G S   ES  +   T    P    
Sbjct: 593  QWQKYRSVSQDIDSW--RSICSYSKYHFQIRAVNSIGTSAPTESS-LSYSTPAAKPDTNP 649

Query: 1772 XXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQ 1827
                    D +S+ I+W   ++     P   YKV        G  W            + 
Sbjct: 650  ENVMTLSTDPKSMIISWQEMDRRQFNGPGFQYKVFWRRAADSGAHW-TESSVSNPPLMVN 708

Query: 1828 KLSINTTYQFRIYARNEIGTS-LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
                  +++ ++ A N++G +  P T    I       P   P    V+E    SV ++W
Sbjct: 709  NTGTFVSFEIKVQAVNDLGAAPEPLT---VIGYSGEDFPLEAPSALSVTELQKTSVMVRW 765

Query: 1887 T--EPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHEHCIE---NIKEKDEIIFRI 1940
            +   PES  G  +  Y I +  +KG  W T    V  S +   IE   +  EK     + 
Sbjct: 766  SPVRPESVRGH-LLGYKI-YLRMKGSQWETPGRAVSSSGNPTVIEVPADAAEKIVSDLQF 823

Query: 1941 SAENTVGV-SLPTESQSVRLEKHATVPSPPTAP---LEIRMVGSNIVMTSWGTPEWDGGA 1996
             ++ T+ + +  ++ +    E+  + P     P   L       + +   W  P    G 
Sbjct: 824  YSDYTLTITAFNSKGEGPHSEESFSTPEGAPGPVLFLPFDSPSESEITLRWEAPHKPNG- 882

Query: 1997 PLLGYNIAIRDVT--KTMWMEVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             + GY +  ++V         V  +D+  + +F +++L+    Y   + ARN+ G   P
Sbjct: 883  EIRGYLLQYQEVVIGSESPQHVESIDLPAVTEFTLKNLNPESRYTFHLSARNDAGDGAP 941



 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 107/446 (23%), Positives = 169/446 (37%), Gaps = 31/446 (6%)

Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR--DESCTAEVT 1101
            T +V W+R    + P + K  +  R     L I N    D+GEY C  R  + S     T
Sbjct: 206  TPEVHWDRIDSALSPNRTKKLYNNRW----LQIDNVLESDDGEYVCTARNSENSVKHHYT 261

Query: 1102 V-VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGK 1159
            V VE  P      +      G     + +     A  + W  +G  +  ++ +       
Sbjct: 262  VTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTD-VDPRRRVS 320

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN----TDAY 1215
              KL + + +  D   Y CE  N   + ++          + LP  IL P        A 
Sbjct: 321  SGKLILSNVEFSDTAVYQCEAVNKHGSILINTHV----HVVELPAQILTPDERLYQATAG 376

Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
             TV +   T      K    I D+        IS     +L I   +E+D   YTC + +
Sbjct: 377  QTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSLKISNVSEEDSNRYTCSVSE 436

Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA---FPQPNDEWIVNS-KII 1328
               +    VEV+    KIV   +   + RGSD  L   Y        P  +W  +  KI 
Sbjct: 437  TNKSISADVEVLN-RTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDGHKIT 495

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
                + K        SL +  V+  D GIY   +            +T+ DKP PP    
Sbjct: 496  ASTSNDK--YHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSDTASGYITVQDKPDPPQSLK 553

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT---EWISVKNITKTQTSIQNLKT 1445
            + E    S+ I W  P    NS +  YV+E  E +T    +W   +++++   S +++ +
Sbjct: 554  LSEKMERSVTISW-MPSVENNSPVTEYVIEMNEGETPDEGQWQKYRSVSQDIDSWRSICS 612

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYY 1471
             S Y F+  AVN +  S  +E++  Y
Sbjct: 613  YSKYHFQIRAVNSIGTSAPTESSLSY 638



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 86/342 (25%), Positives = 138/342 (40%), Gaps = 34/342 (9%)

Query: 860  PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
            P P + W R +  +SP+ T        N  L I NV  E D G+Y C A NS     H  
Sbjct: 205  PTPEVHWDRIDSALSPNRTKKLY---NNRWLQIDNV-LESDDGEYVCTARNSENSVKH-- 258

Query: 920  RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISG--MDHREI 975
              T+ VE   +     + +    G+TV L+C+       +  W  N   +SG  +D R  
Sbjct: 259  HYTVTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTDVDPRRR 318

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL-----QDFEVKE 1030
            +  G+            D  V +C   ++  S ++     + E   ++     + ++   
Sbjct: 319  VSSGK---LILSNVEFSDTAVYQCEAVNKHGSILINTHVHVVELPAQILTPDERLYQATA 375

Query: 1031 KDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
                +L+     S    + WE    I      K      G ++   I N S  D   Y+C
Sbjct: 376  GQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSLK---ISNVSEEDSNRYTC 432

Query: 1090 ILRD--ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDG 1143
             + +  +S +A+V V+    +I+   QN  V +G+ A    + T    L    V+W KDG
Sbjct: 433  SVSETNKSISADVEVLN-RTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDG 491

Query: 1144 SEI--QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183
             +I    SN     I+G    LK+ D  ++D G YSCEV  +
Sbjct: 492  HKITASTSNDKYHEIEG---SLKVLDVQMEDMGIYSCEVSTT 530



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 101/421 (23%), Positives = 163/421 (38%), Gaps = 39/421 (9%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  + L+C    +P P++ W      + P  N +  + ++       L+I NV +  +G 
Sbjct: 192  GQTLTLQCIPEGLPTPEVHWDRIDSALSP--NRTKKLYNNRW-----LQIDNVLESDDGE 244

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y   A N E        +   T E  P     P +  +   GE+V L  +  G P P IT
Sbjct: 245  YVCTARNSENSVKHHYTV---TVEAAPYWTRSP-EEHLYAPGETVRLDCKADGIPAPNIT 300

Query: 768  WCKNNKPVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            W  N  PV            S   IL   +  D  VY  +A N  G    +  + V E  
Sbjct: 301  WSINGVPVSGTDVDPRRRVSSGKLILSNVEFSDTAVYQCEAVNKHGSILINTHVHVVELP 360

Query: 827  EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDG 885
             +   P     R  + T  +  T+ L  R   +P+P I W   + I + S   I+Q  +G
Sbjct: 361  AQILTPD---ERLYQATAGQ--TVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNG 415

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
                L I+NV SE DS  Y C    S  +++      ++V   T +    ++     G  
Sbjct: 416  ---SLKISNV-SEEDSNRYTC----SVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSD 467

Query: 946  VILECQ--TSHTV---STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
             IL C+    H +   + +W  +  +I+     +   E              D+G+  C 
Sbjct: 468  AILHCKYTVDHNLKSPTVQWNKDGHKITASTSNDKYHE-IEGSLKVLDVQMEDMGIYSCE 526

Query: 1001 VK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAIL---EVEINSETADVVWE-RDG 1053
            V    D +T++  +  +  P+  + L+  E  E+ V I     VE NS   + V E  +G
Sbjct: 527  VSTTLDSDTASGYITVQDKPDPPQSLKLSEKMERSVTISWMPSVENNSPVTEYVIEMNEG 586

Query: 1054 E 1054
            E
Sbjct: 587  E 587



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 83/375 (22%), Positives = 148/375 (39%), Gaps = 25/375 (6%)

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802
            S +V +G+++ L     G P P + W + +  +    TK   +   + I    +  D+G 
Sbjct: 186  SYLVLRGQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLYNNRWLQIDNVLE-SDDGE 244

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y   A NSE   +    +TVE         P +    +E       T++L  +    P P
Sbjct: 245  YVCTARNSENSVKHHYTVTVE-------AAPYWTRSPEEHLYAPGETVRLDCKADGIPAP 297

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
            +ITW  N   +S ++   +       +L+++NV+   D+  Y+C A N  G       V 
Sbjct: 298  NITWSINGVPVSGTDVDPRRRVSSG-KLILSNVEFS-DTAVYQCEAVNKHGSILINTHVH 355

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYHNKKEISGMDHREIIQEGRX 981
            +       +   ++ Y+   G+TV+L+C+T  +   K  +     I  + + +I Q    
Sbjct: 356  VVELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQT-TN 414

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE-TIPEFIRKLQDFEVKEKDVAILE--- 1037
                       D     C V +   S    V+     + +   Q+  V     AIL    
Sbjct: 415  GSLKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKY 474

Query: 1038 -VEINSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----IL 1091
             V+ N ++  V W +DG +I     N    E  G ++ L   +  + D G YSC     L
Sbjct: 475  TVDHNLKSPTVQWNKDGHKITASTSNDKYHEIEGSLKVL---DVQMEDMGIYSCEVSTTL 531

Query: 1092 RDESCTAEVTVVELP 1106
              ++ +  +TV + P
Sbjct: 532  DSDTASGYITVQDKP 546



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 24/317 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P +++ P+      G  + L+C+   IP P+I W   G   VP     V  +    +   
Sbjct: 268 PYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSING---VPVSGTDV--DPRRRVSSG 322

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESV 752
            L ++NV+      Y   AVN+ G  S+ I   +   E  P Q++ P + +     G++V
Sbjct: 323 KLILSNVEFSDTAVYQCEAVNKHG--SILINTHVHVVEL-PAQILTPDERLYQATAGQTV 379

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENS 810
           +L  +  G+P P I W    + + ++P  S+      T   LK   V +E         S
Sbjct: 380 MLDCRTFGSPLPKIHW----EILDSIPALSNAKISQTTNGSLKISNVSEEDSNRYTCSVS 435

Query: 811 EGIAETSAVITVEEPTEENAEPP-LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
           E     SA + V   T+    P  L + R  +  +  K T+    +      P++ W ++
Sbjct: 436 ETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYTVDHNLK-----SPTVQWNKD 490

Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929
              I+ S +  +  + E   L + +V  E D G Y C  S +    +    +T+  +K  
Sbjct: 491 GHKITASTSNDKYHEIEG-SLKVLDVQME-DMGIYSCEVSTTLDSDTASGYITVQ-DKPD 547

Query: 930 FVKHLQKSYETEEGKTV 946
             + L+ S + E   T+
Sbjct: 548 PPQSLKLSEKMERSVTI 564



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 68/328 (20%), Positives = 123/328 (37%), Gaps = 23/328 (7%)

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPP------GKPNILEIDSSSINICWDEPENTGN 1409
            G Y+    N  G A V   V +  +P P        K    E+  S++  C + P+++  
Sbjct: 43   GTYRCYAANELGTA-VSNLVHLTTEPVPSLAKVKKQKRRAYEVGESAVLRC-NPPKSSVT 100

Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS---YRFRAYAVNEVDISDASE 1466
              I +  +++  I   E +++           NL  N S   Y   A+ +N   I     
Sbjct: 101  PKIHWMDMQFHHIPLNERVTISR--DGNLYFANLIANDSRDDYTCNAHYINASIILPKEP 158

Query: 1467 TTEYY----KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
             + Y      V+K  + +         +      + + L CI  G+P P+V W R    L
Sbjct: 159  MSIYVTPSNSVVKNRRAKLHHPAGARSSYLVLRGQTLTLQCIPEGLPTPEVHWDRIDSAL 218

Query: 1523 --KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580
                 K  Y NR               Y C A N    V+    V ++  P  T S E+ 
Sbjct: 219  SPNRTKKLYNNR-WLQIDNVLESDDGEYVCTARNSENSVKHHYTVTVEAAPYWTRSPEE- 276

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
               +  G+   +    +GIP P + W  NG  + +  + +   +  +  + +  ++ S +
Sbjct: 277  -HLYAPGETVRLDCKADGIPAPNITWSINGVPV-SGTDVDPRRRVSSGKLILSNVEFSDT 334

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
            + Y  EA N  G+  +   + V + P++
Sbjct: 335  AVYQCEAVNKHGSILINTHVHVVELPAQ 362



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T+  +C  EG P P++ W R  + + P++  ++Y    N   L I  V   D G + C
Sbjct: 192 GQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLY----NNRWLQIDNVLESDDGEYVC 247

Query: 584 VAKNAAGFASSTTELIVEA 602
            A+N+         + VEA
Sbjct: 248 TARNSENSVKHHYTVTVEA 266


>UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6;
            Eumetazoa|Rep: Receptor tyrosine phosphatase - Hirudo
            medicinalis (Medicinal leech)
          Length = 2051

 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 103/464 (22%), Positives = 172/464 (37%), Gaps = 24/464 (5%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISD-ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498
            ++ +K     R+   A N V + D  S     Y          P +    K  + E    
Sbjct: 93   VEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVERYRS 152

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556
              + C   G P+P  +W +D   ++     +                    Y+CIA N H
Sbjct: 153  TVMACSGKGNPEPTFSWLKDFIPIEFTPVRFSVMPTGALQLLNSTYSYEGKYECIAENSH 212

Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
            G   +     + +   I      +    +V  G    +T +  G P P ++W +N   L 
Sbjct: 213  GVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMWKRNNLDLS 272

Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674
            +    +      T V+R++ +  + S+ YT  A +  GT+S  V +KV   P KP   + 
Sbjct: 273  HRSNNH---SHGTGVLRLEGI--TESANYTCHAISELGTASHVVQVKVNVLP-KPPSSLW 326

Query: 1675 MREISRESVTIEWKPPLDDG-GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733
            + E+S  +V ++W P   D     + ++      PDN  + +  DV  D   + I +L  
Sbjct: 327  ITEVSPNTVHLKWSPGNSDPVDSYIIRFRPRYSHPDN--FTEFTDVGSDTTDHHIARLIR 384

Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793
              EY FRV A N +G S +  S P+ + T   VP           +   +V +T   +  
Sbjct: 385  YTEYEFRVYAVNKLGRSAS--STPVDVVTGELVPGSEPPNVRARPVSGTTVVVTMGRTNH 442

Query: 1794 NGGSPIIDYKV-----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848
                    YKV      +      W            +  L  N TY   + A   +G  
Sbjct: 443  CATGSYKGYKVYYTGQPVVTPVSLWTLHIVENSHLTTLTNLKENHTYTISVLAFTSVGDG 502

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892
             P +  D + +      P QP NF+    +S S+ ++W  P SN
Sbjct: 503  -PLS--DNVQVFTRPGVPDQPTNFLGESVSSTSIHIQWDRPASN 543



 Score = 84.2 bits (199), Expect = 4e-14
 Identities = 76/297 (25%), Positives = 126/297 (42%), Gaps = 19/297 (6%)

Query: 637 SKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695
           S+ P+  Q V EG+     C +V  P P++ W     ++        + +   H   SVL
Sbjct: 32  SRPPRVVQKVMEGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVL 91

Query: 696 KITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKEP-----PQVIEPLKSMIVRQG 749
           ++  VKK  EG Y   A N  G    +   L + T + +P     P+++   K   V + 
Sbjct: 92  RVEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYT-KNDPIPAGFPEILVHPKLGSVERY 150

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAE 808
            S +++    GNP PT +W K+  P++  P + S   T ++ +L       EG Y   AE
Sbjct: 151 RSTVMACSGKGNPEPTFSWLKDFIPIEFTPVRFSVMPTGALQLLN-STYSYEGKYECIAE 209

Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
           NS G+  +     V    +    PP F        V   G++ L    + +P P I W R
Sbjct: 210 NSHGVTNSQQATLV---LKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMWKR 266

Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           NN  +S       +  G      +  ++   +S +Y C A +  G +SH  +V ++V
Sbjct: 267 NNLDLSHRSNNHSHGTG------VLRLEGITESANYTCHAISELGTASHVVQVKVNV 317



 Score = 75.8 bits (178), Expect = 1e-11
 Identities = 114/487 (23%), Positives = 184/487 (37%), Gaps = 42/487 (8%)

Query: 1596 IEGIPPPEVIWYKNGNKLEN----DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            + G P PE+ WY    KLE+         I T    SV+R++ +K+    +Y  EA N  
Sbjct: 53   VVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVLRVEPVKKRDEGRYECEAHNGV 112

Query: 1652 GTSS-VEVTLKVYDKPSK-PEG-PVIMREISRESVTIEWKPPL---DDGGLELTKYAIEK 1705
            G    V   L VY K    P G P I+      SV       +     G  E T   ++ 
Sbjct: 113  GVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVERYRSTVMACSGKGNPEPTFSWLKD 172

Query: 1706 HEPDNNRWIKVADVDRDV-ETYCIQKLNENCEY--MFRVIAQNPVGFSEALESEPIVIKT 1762
              P     I+   V   V  T  +Q LN    Y   +  IA+N  G + + ++  +V+K 
Sbjct: 173  FIP-----IEFTPVRFSVMPTGALQLLNSTYSYEGKYECIAENSHGVTNSQQAT-LVLKA 226

Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822
                P           +   S+ +T   S    GSP  +  +  K+              
Sbjct: 227  RRIPPHFSALPDNAEVVHGGSLNLTCIAS----GSP--EPFIMWKRNNLDLSHRSNNHSH 280

Query: 1823 XARIQKLS-INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881
               + +L  I  +  +  +A +E+GT+        +   K    P  P +  ++E +  +
Sbjct: 281  GTGVLRLEGITESANYTCHAISELGTA------SHVVQVKVNVLPKPPSSLWITEVSPNT 334

Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939
            V LKW+   S+   P+ +YII F+       ++T+   VG    +H I  +    E  FR
Sbjct: 335  VHLKWSPGNSD---PVDSYIIRFRPRYSHPDNFTEFTDVGSDTTDHHIARLIRYTEYEFR 391

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999
            + A N +G S    S  V +     VP      +  R V    V+ + G           
Sbjct: 392  VYAVNKLGRS--ASSTPVDVVTGELVPGSEPPNVRARPVSGTTVVVTMGRTNHCATGSYK 449

Query: 2000 GYNIAI--RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
            GY +    + V   + +    +  N+    + +L ENHTY I + A   +G   PL  + 
Sbjct: 450  GYKVYYTGQPVVTPVSLWTLHIVENSHLTTLTNLKENHTYTISVLAFTSVG-DGPLSDNV 508

Query: 2058 PFKVIPG 2064
                 PG
Sbjct: 509  QVFTRPG 515



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 74/328 (22%), Positives = 120/328 (36%), Gaps = 35/328 (10%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPEDAG 579
           +G+   F C V G P P++TW+     ++     Q  +  +   N++ L +  V   D G
Sbjct: 43  EGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVLRVEPVKKRDEG 102

Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639
            + C A N  G     +  +     +D                     I  G P      
Sbjct: 103 RYECEAHNGVGVPDRVSFNLSVYTKND--------------------PIPAGFPEILVH- 141

Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
           PK   V+     ++ C     PEP  +WL   ++ +P E   V       M    L++ N
Sbjct: 142 PKLGSVERYRSTVMACSGKGNPEPTFSWL---KDFIPIEFTPVRFSV---MPTGALQLLN 195

Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
                EG Y  +A N  G  +      +    + PP       +  V  G S+ L+    
Sbjct: 196 STYSYEGKYECIAENSHGVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIAS 255

Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
           G+P P I W +NN     L  +S+  +H   +L+ + + +   YT  A +  G A  S V
Sbjct: 256 GSPEPFIMWKRNNLD---LSHRSNNHSHGTGVLRLEGITESANYTCHAISELGTA--SHV 310

Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEK 847
           + V+          L+I      TV  K
Sbjct: 311 VQVKVNVLPKPPSSLWITEVSPNTVHLK 338



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 63/280 (22%), Positives = 116/280 (41%), Gaps = 22/280 (7%)

Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781
            D+ +  +  L +   Y   V   N  G  E   S+ I++KT  D+P           +++
Sbjct: 690  DLRSATLHDLKKFTAYKIWVAGYNRAG--EGPLSDVIIVKTEEDIPGEPKRVKVEA-LNS 746

Query: 1782 ESVYITWFP---SEKNGGSP--IIDYKVEIKQEGKKWKXXXXXXXXXAR----IQKLSIN 1832
             SV++ W      E NG     ++ Y    + E +K++          +    I  LS +
Sbjct: 747  TSVHLEWKAPQDGEHNGDIKGYVVFYTELDENEEEKFEPVRSDPLSSHQTELTIGGLSPS 806

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS--ESTSRSVTLKWTEPE 1890
            T YQF++ A    G     +   K+     +  PS P+ F +S  +  +  V + W +P+
Sbjct: 807  TLYQFQVCAYTRKGDG-DKSKSKKVKTKAAV--PSPPKGFTLSLMKEENPIVLVTWQDPK 863

Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950
             + G  I  Y++ F  VKG+S  +     G++H      +++     F+I+A+N VG   
Sbjct: 864  FSHGV-IEGYLVAFG-VKGESHVEERRFNGNIHRFITPFLEKGATYEFKIAAKNAVGYG- 920

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990
              E  +  +      PS     L   ++G++ +   W  P
Sbjct: 921  --EYATEVITTPDGAPSGAPQNLSAAVLGAHTIRLHWDPP 958



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 84/387 (21%), Positives = 148/387 (38%), Gaps = 43/387 (11%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQ----LTIDGKK 1160
            PP ++     QKV +GN ATF   +  K    + W+    +++   + Q    +      
Sbjct: 34   PPRVV-----QKVMEGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNL 88

Query: 1161 QKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP--ANTD 1213
              L++      D G Y CE  N      + +  L+V   +       PE ++ P   + +
Sbjct: 89   SVLRVEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVE 148

Query: 1214 AYLTVEI-------PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266
             Y +  +       P+ T   +W K    IE T      S +    L +   T   + +Y
Sbjct: 149  RYRSTVMACSGKGNPEPTF--SWLKDFIPIEFTP--VRFSVMPTGALQLLNSTYSYEGKY 204

Query: 1267 TCVLLDAKSTTK-----LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
             C+  ++   T      L ++    PP          +  G  + L       P+P   W
Sbjct: 205  ECIAENSHGVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMW 264

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              N+  +    H   +    +  L ++ +  T++  Y     +  G A   + V +   P
Sbjct: 265  KRNNLDLS---HRSNNHSHGTGVLRLEGI--TESANYTCHAISELGTASHVVQVKVNVLP 319

Query: 1382 SPPGKPNILEIDSSSINICWDEPENTG--NSTIIYYVVEYQEIDT-TEWISVKNITKTQT 1438
             PP    I E+  +++++ W  P N+   +S II +   Y   D  TE+  V + T T  
Sbjct: 320  KPPSSLWITEVSPNTVHLKWS-PGNSDPVDSYIIRFRPRYSHPDNFTEFTDVGSDT-TDH 377

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             I  L   + Y FR YAVN++  S +S
Sbjct: 378  HIARLIRYTEYEFRVYAVNKLGRSASS 404



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 54/235 (22%), Positives = 93/235 (39%), Gaps = 18/235 (7%)

Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885
            I +L   T Y+FR+YA N++G S   T  D +T G+ L P S+P N      +  +V + 
Sbjct: 379  IARLIRYTEYEFRVYAVNKLGRSASSTPVDVVT-GE-LVPGSEPPNVRARPVSGTTVVVT 436

Query: 1886 WTEPESNGGSPITNYIIEFK----TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941
                          Y + +           WT  + +  + H   + N+KE       + 
Sbjct: 437  MGRTNHCATGSYKGYKVYYTGQPVVTPVSLWT--LHIVENSHLTTLTNLKENHTYTISVL 494

Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001
            A  +VG   P  S +V++     VP  PT  L    V S  +   W  P  +    ++ Y
Sbjct: 495  AFTSVGDG-PL-SDNVQVFTRPGVPDQPTNFLG-ESVSSTSIHIQWDRPASNN---IVRY 548

Query: 2002 NIAIRD--VTKTMWMEVG--KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
             +   D        +++G  + D   + + + DL+ +  Y + + A  E G   P
Sbjct: 549  KLRYMDSNTRSNFSVDIGRKRQDQRIIWYLLTDLAASTVYHMTLSAVAEGGEGPP 603



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 4/98 (4%)

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILE---IDSSSINICWDEP-ENTGNSTII 1413
            +K+  +N  G+ +    V      +P G P  L    + + +I + WD P +   +  I 
Sbjct: 909  FKIAAKNAVGYGEYATEVITTPDGAPSGAPQNLSAAVLGAHTIRLHWDPPVKKLRHGVIQ 968

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451
             Y V Y E D      + N T+T   +  L+ + SY F
Sbjct: 969  MYEVVYCESDDPGQDVMVNTTETSLVVDKLEADRSYTF 1006


>UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB,
            isoform B; n=3; Apocrita|Rep: PREDICTED: similar to
            CG32387-PB, isoform B - Apis mellifera
          Length = 792

 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 111/535 (20%), Positives = 209/535 (39%), Gaps = 40/535 (7%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP F+++     +  G  I+L C    IP P   W     E V    +    E  ++  
Sbjct: 188  VPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWF---RESVTGTAMIFNSER-IYAR 243

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              VL + + +    G Y   A N  G   + + + I +        + P + + V  G+ 
Sbjct: 244  AGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIH---LVP-QQVTVDLGKD 299

Query: 752  VILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAE 808
                  V G P P I W K+  PV    +   K  G+  S   +      D+G+Y   A+
Sbjct: 300  AEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAK 359

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N   + + +A + + +        P  + +F E T++   ++ L    T NP P  +W  
Sbjct: 360  NDYEMVQATAELRLGDAA------PQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTL 413

Query: 869  NNEIISPSET--ITQ--NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            +   +  ++   I Q     G+ I  V  +V    D G+Y+C A+N   K  H AR  ++
Sbjct: 414  DGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSAR--LN 471

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXX 982
            +  +  V+ +  +Y    G+T +++C  +     S  W  + K +     +E+   G   
Sbjct: 472  IYGLPHVRPM-GNYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNG--T 528

Query: 983  XXXXXXXXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFIRKLQ---DFEVKEKDVAIL 1036
                      D G   C  K+++    S  + ++  +P  I       + +   +   + 
Sbjct: 529  LVLHHVDRSTDHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVHVVC 588

Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096
             V        + W +DG  +   +          +  +    T+ H+ G Y+C+  +++ 
Sbjct: 589  VVSEGDSPLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHN-GNYTCVASNDAA 647

Query: 1097 TAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEI 1146
                T   +V +PP I     N+ +++G +A     + KGD    + W KDG  I
Sbjct: 648  ETSRTASLLVHVPPTIAPFSFNKDLSEGVRAQVTCMVEKGDPPFTIAWSKDGEAI 702



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 8/187 (4%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXX 1543
            +P+ N      E   + C   G P   +TW +DGK L T++    + N            
Sbjct: 479  RPMGNYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNGTLVLHHVDRST 538

Query: 1544 XXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISN--EDIKQKHKVGDEWLVTAVIEGIP 1600
                Y C A N  G  ++  V + ++  P I   +   +I++  +V    +V  V EG  
Sbjct: 539  DHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVH---VVCVVSEGDS 595

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
            P ++ W K+G  L + +       E    + I+    +H+  YT  ASN A  +S   +L
Sbjct: 596  PLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAAETSRTASL 655

Query: 1661 KVYDKPS 1667
             V+  P+
Sbjct: 656  LVHVPPT 662



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 1/106 (0%)

Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
           T     + P F E++ P     G T+   C  +G P P   WFR+ ++   +  F     
Sbjct: 182 TDPHTPVPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRE-SVTGTAMIFNSERI 240

Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607
                 LV++    EDAG + C A N AG      E+ + + LS H
Sbjct: 241 YARAGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIH 286



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 69/301 (22%), Positives = 116/301 (38%), Gaps = 40/301 (13%)

Query: 639 KPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697
           +P   Y    G   +++C +   P   I W   G+ ++P         +   +   V + 
Sbjct: 479 RPMGNYAAVAGETTVIKCPVAGFPIASITWEKDGK-VLPTSRRQEVFPNGTLVLHHVDRS 537

Query: 698 TNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILS 755
           T+      G YT  A N++G + S  + +++K     PP+ I+P      +++G  V + 
Sbjct: 538 TD-----HGAYTCTAKNKQGRSDSQTVHIEVKV----PPK-IDPFSFPANIQEGARVHVV 587

Query: 756 AQVVGNPRPT-ITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEG 812
             V     P  ITW K+ +P+ +  T +   G+     +++       G YT  A N   
Sbjct: 588 CVVSEGDSPLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAA 647

Query: 813 IAETSAVITVEEPTEENAEPPLFIN-------RFQEITVKEKGTIKLVARVTRN------ 859
               +A + V  P       P   N       R Q   + EKG        +++      
Sbjct: 648 ETSRTASLLVHVPP---TIAPFSFNKDLSEGVRAQVTCMVEKGDPPFTIAWSKDGEAIAG 704

Query: 860 PVPSITWYRNNEIISPSETITQ------NFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
           P P+   + N  I  P  T T       N D  +  +VI  V S   SG+Y C+A NS  
Sbjct: 705 PSPAAAGFGNTGITGPRHTQTPAGLRVTNIDAHSSTIVIERV-SAAHSGNYTCMARNSVA 763

Query: 914 K 914
           +
Sbjct: 764 E 764



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 49/219 (22%), Positives = 82/219 (37%), Gaps = 14/219 (6%)

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP--- 1495
            S+ +    SSYR R   V+ V   D  E++ Y +++  T   +P   +  + ++  P   
Sbjct: 148  SVTSSDAQSSYRCRT--VHRVT-GDTVESSSYARLVV-TDPHTPVPPRFNERVSPAPIRT 203

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551
             E I L+CI  G+P P   W+R+       +  ++  Y                  Y C 
Sbjct: 204  GETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSERIYARAGVLVLQSARAEDAGRYVCH 263

Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            A N  G       V I     I +  + +     +G +      + G P P + W K+G 
Sbjct: 264  ANNTAGSEMVELEVSIISSLSIHLVPQQVTV--DLGKDAEFQCSVTGQPIPVIFWTKDGL 321

Query: 1612 KL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649
             + E+    +  T    S +RI  + R     Y   A N
Sbjct: 322  PVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKN 360



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 23/75 (30%), Positives = 34/75 (45%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G   +F+C V G P P I W +    +  S   +     ++ +TL I  V  +D G + C
Sbjct: 297 GKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQC 356

Query: 584 VAKNAAGFASSTTEL 598
            AKN      +T EL
Sbjct: 357 FAKNDYEMVQATAEL 371



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 6/82 (7%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV-FPEDAGTFT 582
           G T   +C V G+P   ITW +   ++  S+  +++ +     TLV+  V    D G +T
Sbjct: 489 GETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPN----GTLVLHHVDRSTDHGAYT 544

Query: 583 CVAKNAAGFA-SSTTELIVEAP 603
           C AKN  G + S T  + V+ P
Sbjct: 545 CTAKNKQGRSDSQTVHIEVKVP 566



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 42/204 (20%), Positives = 76/204 (37%), Gaps = 12/204 (5%)

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRX 1533
            I S ++    + +T +  +D E  C   G P P + W +DG  +       +K T  +  
Sbjct: 280  ISSLSIHLVPQQVTVDLGKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGS 339

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y+C A ND+  V+ +  + +       +  + I+Q  + G    + 
Sbjct: 340  TLRISSVVRDDKGMYQCFAKNDYEMVQATAELRLGD-AAPQLLYKFIEQTIQPGPSVSLK 398

Query: 1594 AVIEGIPPPEVIWYKNGNKL-ENDK----EYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648
             +  G P P   W  +G  L +ND+    +Y     +  S + I  +      +Y   A+
Sbjct: 399  CIATGNPTPHFSWTLDGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAA 458

Query: 1649 NTAGTSSVEVTLKVYDKPS-KPEG 1671
            N          L +Y  P  +P G
Sbjct: 459  NRMAKVHHSARLNIYGLPHVRPMG 482



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 18/81 (22%), Positives = 42/81 (51%), Gaps = 6/81 (7%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKN---GNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641
            + G+  +++ + +GIPPP  +W++    G  +  + E       +  V+ ++  +   + 
Sbjct: 202  RTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSE---RIYARAGVLVLQSARAEDAG 258

Query: 1642 KYTIEASNTAGTSSVEVTLKV 1662
            +Y   A+NTAG+  VE+ + +
Sbjct: 259  RYVCHANNTAGSEMVELEVSI 279



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 46/231 (19%), Positives = 92/231 (39%), Gaps = 15/231 (6%)

Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKD---GSEIQFSNHIQLTIDGK 1159
            +PP    R+    +  G        +++G    +  WF++   G+ + F++     I  +
Sbjct: 188  VPPRFNERVSPAPIRTGETIVLSC-ISQGIPPPMYLWFRESVTGTAMIFNSE---RIYAR 243

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI-NFTLRL-PEFILVPANTDAYLT 1217
               L +     +DAG Y C   N+  + ++ +E   I + ++ L P+ + V    DA   
Sbjct: 244  AGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDAEFQ 303

Query: 1218 VEIPDETLDVTWYKKKS--VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275
              +  + + V ++ K    V E     + I+     TL I     DD+  Y C   +   
Sbjct: 304  CSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKNDYE 363

Query: 1276 TTKLKVE--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324
              +   E  + +  P+++    E  I+ G  V+L       P P+  W ++
Sbjct: 364  MVQATAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLD 414


>UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttnl
           protein - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 384

 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 76/356 (21%), Positives = 155/356 (43%), Gaps = 33/356 (9%)

Query: 491 KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550
           ++   P+ + PT ++++  P F  +L+       + V+   ++ G  +P I+W +    +
Sbjct: 35  RVKSPPMVKSPTPKDKTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNL 94

Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS----D 606
                ++++ ++   A L I +    D+G +TC A+N+ G  S+   L ++A  +    +
Sbjct: 95  SQGGKYEIF-EEHGSAHLEIYDADLSDSGVYTCTAQNSVGSVSTNCTLTIQARTTAAALE 153

Query: 607 HGSEMT---VXXXXXXXXXXXXADI-----------LEGIPPTFSKKPKAQYVDEGSDIL 652
             SE+T   V             +I                P+F  +P +Q V+EG ++ 
Sbjct: 154 GKSELTEEIVKKENTYEEVQSYTEIKASKTQMTVSATHSGSPSFLVQPHSQNVNEGQNVT 213

Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
             C +   P P++ WL     I    N+ ++   +++     L+I N      G +TV A
Sbjct: 214 FTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVY----TLEIHNATIEDSGKFTVKA 269

Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            N+ G+ S    L + +    PP++    + + +  G+ + ++    G+P P I W  + 
Sbjct: 270 KNKFGQCSATASLNVLS---VPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSG 326

Query: 773 KPVKA------LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
           K + +      L  ++  D  ++ I   K+  D G YTLK  N  G   T+  +++
Sbjct: 327 KTLSSKEESGRLQIENSQDVTTLFISAVKET-DAGAYTLKLSNEFGSDTTTVNVSI 381



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 5/137 (3%)

Query: 464 EEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD 523
           E K  +  + +  EN Y + +Q     K  K    +   S   S +P F+ +   ++  +
Sbjct: 153 EGKSELTEEIVKKENTYEE-VQSYTEIKASKT---QMTVSATHSGSPSFLVQPHSQNVNE 208

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V F C++ G P P++ W +  A+I  + + ++     NV TL I     ED+G FT 
Sbjct: 209 GQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKL-SRSKNVYTLEIHNATIEDSGKFTV 267

Query: 584 VAKNAAGFASSTTELIV 600
            AKN  G  S+T  L V
Sbjct: 268 KAKNKFGQCSATASLNV 284



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 6/167 (3%)

Query: 1217 TVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--A 1273
            T EI  E + +V W K  +VI  T    L       TL I   T +D  ++T    +   
Sbjct: 215  TCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVKAKNKFG 274

Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333
            + +    + V+  PPKI    R+  I+ G  +++   +   P P  EW  + K +   + 
Sbjct: 275  QCSATASLNVLSVPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEE 334

Query: 1334 T-KPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            + +  I++     +L I  V+ TDAG Y L+L N  G     +NV+I
Sbjct: 335  SGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSI 381



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 43/187 (22%), Positives = 83/187 (44%), Gaps = 10/187 (5%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165
            P  + +  +Q VN+G   TF  E+T +    V W KD + I  +++++L+       L+I
Sbjct: 195  PSFLVQPHSQNVNEGQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEI 254

Query: 1166 YDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLR-LPEFILV-PANTDAYLTVEIP 1221
            ++  ++D+G+++ +  N   +C+A  ++   S+   +   P  I + P    +       
Sbjct: 255  HNATIEDSGKFTVKAKNKFGQCSATASLNVLSVPPKIEAAPRDISIEPGKVLSVACAFTG 314

Query: 1222 DETLDVTWY---KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276
            D T  + W    K  S  E++ +  + +     TL I    E D   YT  L +     T
Sbjct: 315  DPTPCIEWSHSGKTLSSKEESGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDT 374

Query: 1277 TKLKVEV 1283
            T + V +
Sbjct: 375  TTVNVSI 381



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 41/183 (22%), Positives = 72/183 (39%), Gaps = 8/183 (4%)

Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
           VK E  Y    E  +   E  A  T    +  ++  P F+ +     V E   +     +
Sbjct: 163 VKKENTY----EEVQSYTEIKASKTQMTVSATHSGSPSFLVQPHSQNVNEGQNVTFTCEI 218

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
           T  P P + W ++N +IS +  +  +       L I N   E DSG +   A N  G+ S
Sbjct: 219 TGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIE-DSGKFTVKAKNKFGQCS 277

Query: 917 HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHRE 974
             A + + +     ++   +    E GK + + C  +   T   +W H+ K +S  +   
Sbjct: 278 ATASLNV-LSVPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEESG 336

Query: 975 IIQ 977
            +Q
Sbjct: 337 RLQ 339



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 3/122 (2%)

Query: 822 VEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
           V+ PT ++    P F    ++I+      +KL  +++ +  PSI+W ++ + +S      
Sbjct: 42  VKSPTPKDKTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQGGKYE 101

Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
              +  +  L I + D   DSG Y C A NS G  S    +TI   + T      KS  T
Sbjct: 102 IFEEHGSAHLEIYDADLS-DSGVYTCTAQNSVGSVSTNCTLTIQA-RTTAAALEGKSELT 159

Query: 941 EE 942
           EE
Sbjct: 160 EE 161



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 34/174 (19%), Positives = 65/174 (37%), Gaps = 10/174 (5%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552
            +++  TC   G P P+V W +D   +        +  +N                +   A
Sbjct: 210  QNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVKA 269

Query: 1553 FNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
             N  G+   +  + +    P I  +  DI    + G    V     G P P + W  +G 
Sbjct: 270  KNKFGQCSATASLNVLSVPPKIEAAPRDI--SIEPGKVLSVACAFTGDPTPCIEWSHSGK 327

Query: 1612 KLENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
             L + +E     I   +  + + I  +K + +  YT++ SN  G+ +  V + +
Sbjct: 328  TLSSKEESGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSI 381



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 6/98 (6%)

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NR 1532
            K   P+    LK+I+   +  ++LT    G  +P ++W +DGK L      YE       
Sbjct: 50   KTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQG-GKYEIFEEHGS 108

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570
                           Y C A N  G V T+C + IQ +
Sbjct: 109  AHLEIYDADLSDSGVYTCTAQNSVGSVSTNCTLTIQAR 146



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 2/95 (2%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G     T  I G P PEV W K+   +       ++  +    + I       S K+T++
Sbjct: 209  GQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVK 268

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681
            A N  G  S   +L V   P K E     R+IS E
Sbjct: 269  AKNKFGQCSATASLNVLSVPPKIE--AAPRDISIE 301



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK- 793
           P     LK +       V L+ ++ G+ +P+I+W K+ K +         + H    L+ 
Sbjct: 54  PSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLEI 113

Query: 794 -PKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
               + D GVYT  A+NS G   T+  +T++  T
Sbjct: 114 YDADLSDSGVYTCTAQNSVGSVSTNCTLTIQART 147



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 3/79 (3%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            P   T L++   +        ++L+ GD    + W KDG  +      ++  +     L+
Sbjct: 54   PSFSTELKDISASADTIVKLTVKLS-GDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLE 112

Query: 1165 IYDCDLDDAGEYSCEVGNS 1183
            IYD DL D+G Y+C   NS
Sbjct: 113  IYDADLSDSGVYTCTAQNS 131



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 20/71 (28%), Positives = 33/71 (46%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T  + G   P + W K+G  L    +Y I  +  ++ + I +   S S  YT  A N+ 
Sbjct: 73   LTVKLSGDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLEIYDADLSDSGVYTCTAQNSV 132

Query: 1652 GTSSVEVTLKV 1662
            G+ S   TL +
Sbjct: 133  GSVSTNCTLTI 143



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 19/94 (20%), Positives = 37/94 (39%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P  +       +  G +VT   +    P P  EW+ ++ +I    + K S      +L I
Sbjct: 195  PSFLVQPHSQNVNEGQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEI 254

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
                  D+G + ++ +N  G      ++ +L  P
Sbjct: 255  HNATIEDSGKFTVKAKNKFGQCSATASLNVLSVP 288



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 1/98 (1%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           +PP     P+   ++ G  + + C     P P I W   G+ +   E  S  ++ +    
Sbjct: 287 VPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEE-SGRLQIENSQD 345

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729
            + L I+ VK+   G YT+   N  G  +  + + I++
Sbjct: 346 VTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSIRS 383



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 14/43 (32%), Positives = 23/43 (53%)

Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524
            P +E   ++I+ EP + + + C F G P P + W   GK L +
Sbjct: 289  PKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSS 331


>UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 11 SCAF14528, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 786

 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 103/436 (23%), Positives = 189/436 (43%), Gaps = 41/436 (9%)

Query: 785  DTHSITILKPKKVKDEGVYTLKAENS----EGIAETSAVITVEEPTEENAEPPLFINRFQ 840
            +T S+ I K ++  D G YT    N+    + ++  + ++   +      EP + ++  +
Sbjct: 26   ETGSLYIAKVER-SDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPE 84

Query: 841  EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             +   ++  +KL      NPVP I+W R + I  PS+   +N    N  L I N   E D
Sbjct: 85   SVPAAKESAVKLECFALGNPVPEISWRRTSGIPFPSKVKMKN---SNAVLEIPNFQQE-D 140

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVST 958
            +G Y+CVA N  GK++   R++    K  +++ +  +  + E   +  EC+ +     S 
Sbjct: 141  AGTYECVAENRRGKNAARGRLSFHA-KPHWLQTMADTALSIEA-NLFWECKANGKPKPSY 198

Query: 959  KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014
             W  N ++++  + R  I  G             D G+ +C+ +++     +S  L+V  
Sbjct: 199  SWLKNGEQVAA-EGRIQIDNG---ALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLA 254

Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSET---ADVVWERDGEIIKPKKNKYDFEKRGHI 1071
            + P F +      +K +  + + +E   E    A  +W++  EI+ P+  + +    G I
Sbjct: 255  SPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEIL-PRTERINLLPNGTI 313

Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEI 1128
            +   I N +  D G Y+CI +++  TA  T   ++  P  I  R  N ++  G  A    
Sbjct: 314  K---IANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPC 370

Query: 1129 ELTKGDAL---VRWFKDGSEIQF---SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178
            ++    AL     W  +G  I F    NH +         L I +  L   G+Y C    
Sbjct: 371  QIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDT 430

Query: 1179 EVGNSKCTAILTVEEP 1194
            +V +   +AIL V+ P
Sbjct: 431  DVESLSTSAILVVKGP 446



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 125/535 (23%), Positives = 197/535 (36%), Gaps = 51/535 (9%)

Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX-XXXXXXXXXYKCIAFNDHG 1557
            ++L C   G P P+++W R       +K   +N                 Y+C+A N  G
Sbjct: 94   VKLECFALGNPVPEISWRRTSGIPFPSKVKMKNSNAVLEIPNFQQEDAGTYECVAENRRG 153

Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617
            +      +    KP    +  D     +    W   A   G P P   W KNG ++  + 
Sbjct: 154  KNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKA--NGKPKPSYSWLKNGEQVAAEG 211

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVI 1674
               I        + I  L  S S  Y   A N  G       L V   P   SK     +
Sbjct: 212  RIQIDN----GALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASPPNFSKSPLKAL 267

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIE---KHEPDN---NRWIKVADVDR-DVETY- 1726
            ++  S   VT+E KP      + L K   E   + E  N   N  IK+A+  R D  +Y 
Sbjct: 268  LKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPNGTIKIANATRQDAGSYT 327

Query: 1727 CIQKLN-ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785
            CI K          +++   P   +    +  I++  +  +P                V 
Sbjct: 328  CIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQIAFDPAL------DVS 381

Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845
             +W     NG   +ID++    ++G  ++           I+ + ++   ++       I
Sbjct: 382  FSW---AFNG--QLIDFQ----RDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCL----I 428

Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905
             T +   S   I + K   PP  P    V E T  +  L WT P  + GSPIT YII+ +
Sbjct: 429  DTDVESLSTSAILVVKG--PPGPPDKVTVEEITDSTAQLSWT-PGRDNGSPITGYIIQAR 485

Query: 1906 TVKGKSWTKIVTV----GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961
            T     W  + TV     G++    +  +    E  FR+ A N VG+  P+ + S +   
Sbjct: 486  TPFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPSPA-SAKTRT 544

Query: 1962 HATVPSPPTAPLEIRMVG---SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013
              ++P   TAP ++   G   S +V+T    PE        GY IA R +    W
Sbjct: 545  EDSIPD--TAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPLGMVTW 597



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 101/435 (23%), Positives = 174/435 (40%), Gaps = 39/435 (8%)

Query: 695  LKITNVKKFQEGTYTVVAVNR-EGEASL----PIVLKIK--TGEKEPPQVIEPLKSMIVR 747
            L I  V++   G YT V  N   G+  L    P+VL+     GE EP   +   +S+   
Sbjct: 30   LYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPESVPAA 89

Query: 748  QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLK 806
            +  +V L    +GNP P I+W + +      P+K      +  +  P  + +D G Y   
Sbjct: 90   KESAVKLECFALGNPVPEISWRRTSG--IPFPSKVKMKNSNAVLEIPNFQQEDAGTYECV 147

Query: 807  AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
            AEN  G       ++           P ++    +  +  +  +    +    P PS +W
Sbjct: 148  AENRRGKNAARGRLSFH-------AKPHWLQTMADTALSIEANLFWECKANGKPKPSYSW 200

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
             +N E ++    I    D   + + + N+    DSG Y+CVA N  G     A++ +   
Sbjct: 201  LKNGEQVAAEGRI--QIDNGALSIAVLNLS---DSGMYQCVAENKHGIIYSSAQLMVLAS 255

Query: 927  KVTFVKH-LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXX 983
               F K  L+   +   G  V LEC+        + W    + +   +   ++  G    
Sbjct: 256  PPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPNG---T 312

Query: 984  XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEI 1040
                     D G   CI K+Q  +     K  I E  R   +  + E+   + A+L  +I
Sbjct: 313  IKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQI 372

Query: 1041 NSETA-DV--VWERDGEIIKPKKNKYDFEKRGH--IRKLYIRNTSVHDEGEYSCILR--- 1092
              + A DV   W  +G++I  +++   FE+ G      L IRN  +   G+Y C++    
Sbjct: 373  AFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDV 432

Query: 1093 DESCTAEVTVVELPP 1107
            +   T+ + VV+ PP
Sbjct: 433  ESLSTSAILVVKGPP 447



 Score = 76.2 bits (179), Expect = 9e-12
 Identities = 82/331 (24%), Positives = 138/331 (41%), Gaps = 33/331 (9%)

Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699
           P++    + S + LEC  +  P P+I+W            I    +  M    +VL+I N
Sbjct: 83  PESVPAAKESAVKLECFALGNPVPEISWR-------RTSGIPFPSKVKMKNSNAVLEIPN 135

Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759
            ++   GTY  VA NR G+ +     + +      P  ++ +    +    ++    +  
Sbjct: 136 FQQEDAGTYECVAENRRGKNA----ARGRLSFHAKPHWLQTMADTALSIEANLFWECKAN 191

Query: 760 GNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
           G P+P+ +W KN + V A    + D    SI +L    + D G+Y   AEN  GI  +SA
Sbjct: 192 GKPKPSYSWLKNGEQVAAEGRIQIDNGALSIAVL---NLSDSGMYQCVAENKHGIIYSSA 248

Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEK--GTIKLVARVTRNPVPSITWYRNNEIISPS 876
            + V       A PP F     +  +K +    + L  +    P     W + NEI+  +
Sbjct: 249 QLMV------LASPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRT 302

Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
           E I    +G    + I N   + D+G Y C+A N  G +S   ++ I   + T +     
Sbjct: 303 ERINLLPNG---TIKIANATRQ-DAGSYTCIAKNQFGTASTTGKLLI--TEPTRITMRPT 356

Query: 937 SYETEEGKTVILECQTSH----TVSTKWYHN 963
           + E   G++ +L CQ +      VS  W  N
Sbjct: 357 NTEIIVGESAVLPCQIAFDPALDVSFSWAFN 387



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 94/442 (21%), Positives = 157/442 (35%), Gaps = 30/442 (6%)

Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
            C   G P+P  +W ++G+++        +                Y+C+A N HG + +S
Sbjct: 188  CKANGKPKPSYSWLKNGEQVAAEGRIQIDNGALSIAVLNLSDSGMYQCVAENKHGIIYSS 247

Query: 1563 CVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
              + +   P    S   +K   K + G E  +    E  PP   +W K    L   +  N
Sbjct: 248  AQLMVLASPP-NFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERIN 306

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680
            +        I+I    R  +  YT  A N  GT+S    L + +       P     I  
Sbjct: 307  LLPN---GTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVG 363

Query: 1681 ESVT----IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENC 1735
            ES      I + P LD          +   + D N + +V   V  D+    IQ L+   
Sbjct: 364  ESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQ-LSHGG 422

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            +Y+  +         E+L +  I++      P           I + +  ++W P   NG
Sbjct: 423  KYVCLIDTD-----VESLSTSAILVVKG---PPGPPDKVTVEEITDSTAQLSWTPGRDNG 474

Query: 1796 GSPIIDYKVEIKQEGKK-WKXXXXX------XXXXARIQKLSINTTYQFRIYARNEIGTS 1848
             SPI  Y ++ +      W+               A +  L+    Y+FR+ ARN +G  
Sbjct: 475  -SPITGYIIQARTPFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLG 533

Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTV 1907
             P  +  K T  +   P + P +      T   + + W   PE         YII F+ +
Sbjct: 534  EPSPASAK-TRTEDSIPDTAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPL 592

Query: 1908 KGKSWTKIVTVGGSVHEHCIEN 1929
               +WT+       V  +   N
Sbjct: 593  GMVTWTRAAISTPGVARYVFRN 614



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 127/567 (22%), Positives = 207/567 (36%), Gaps = 51/567 (8%)

Query: 1252 TLIIRKCTEDDQCEYTCVL---------LDAKSTTKLKVEVV--EFPPKI-VDYEREYRI 1299
            +L I K    D   YTCV+         L + +   L+ + V  E+ PKI V +      
Sbjct: 29   SLYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPESVPA 88

Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359
             + S V L       P P   W   S I      +K  + + +A L I   +  DAG Y+
Sbjct: 89   AKESAVKLECFALGNPVPEISWRRTSGIPFP---SKVKMKNSNAVLEIPNFQQEDAGTYE 145

Query: 1360 LRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
               EN  G       ++   KP          L I++   N+ W+   N        ++ 
Sbjct: 146  CVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEA---NLFWECKANGKPKPSYSWLK 202

Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
              +++     I + N      SI  L  + S  ++  A N+  I         Y   +  
Sbjct: 203  NGEQVAAEGRIQIDN---GALSIAVLNLSDSGMYQCVAENKHGI--------IYSSAQLM 251

Query: 1478 KIQSPT--VEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENR 1532
             + SP    + PLK +       ++ L C     P P ++ ++ G ++  +T +      
Sbjct: 252  VLASPPNFSKSPLKALLKARSGSEVTLECKPEAWP-PAISLWKKGNEILPRTERINLLPN 310

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592
                           Y CIA N  G   T+  + I +   IT+       +  VG+  ++
Sbjct: 311  GTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITM--RPTNTEIIVGESAVL 368

Query: 1593 TAVIEGIPPPEVI--WYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHSSKYTIEA 1647
               I   P  +V   W  NG  ++  ++ N   +   SV   + I+ ++ SH  KY    
Sbjct: 369  PCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLI 428

Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
                 + S    L V   P  P+  V + EI+  +  + W P  D+G   +T Y I+   
Sbjct: 429  DTDVESLSTSAILVVKGPPGPPD-KVTVEEITDSTAQLSWTPGRDNGS-PITGYIIQART 486

Query: 1708 PDNNRWIKVADVDRDVE----TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            P    W  V  V   +     T  +  LN   EY FRV+A+N VG  E   +     +T 
Sbjct: 487  PFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPSPAS-AKTRTE 545

Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFP 1790
              +P                + ITW P
Sbjct: 546  DSIPDTAPTDVGGGGGTKSELVITWEP 572



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 99/461 (21%), Positives = 168/461 (36%), Gaps = 38/461 (8%)

Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088
            KE  V +    + +   ++ W R   I  P K K     +     L I N    D G Y 
Sbjct: 90   KESAVKLECFALGNPVPEISWRRTSGIPFPSKVKM----KNSNAVLEIPNFQQEDAGTYE 145

Query: 1089 CIL---RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144
            C+    R ++           P  +  + +  ++      +E +   K      W K+G 
Sbjct: 146  CVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKANGKPKPSYSWLKNGE 205

Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTL 1200
            ++     IQ+        L I   +L D+G Y C   N       +A L V     NF+ 
Sbjct: 206  QVAAEGRIQID----NGALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASPPNFS- 260

Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257
            + P   L+ A + + +T+E   E        W K   ++  TE+  L+ +    T+ I  
Sbjct: 261  KSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPN---GTIKIAN 317

Query: 1258 CTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315
             T  D   YTC+  +   T  T  K+ + E P +I        I  G    L       P
Sbjct: 318  ATRQDAGSYTCIAKNQFGTASTTGKLLITE-PTRITMRPTNTEIIVGESAVLPCQIAFDP 376

Query: 1316 --QPNDEWIVNSKII---KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
                +  W  N ++I   +   H +    S S  L I+ ++ +  G Y   ++ +     
Sbjct: 377  ALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDVESLS 436

Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430
                + +   P PP K  + EI  S+  + W  P     S I  Y+++ +   T  W +V
Sbjct: 437  TSAILVVKGPPGPPDKVTVEEITDSTAQLSW-TPGRDNGSPITGYIIQARTPFTVGWQAV 495

Query: 1431 KNITKT------QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
              + +         ++  L     Y FR  A N V + + S
Sbjct: 496  DTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPS 536



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 4/80 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS V  EC+ E +P     W +   I+  ++   +  +     T+ I     +DAG++TC
Sbjct: 273 GSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPN----GTIKIANATRQDAGSYTC 328

Query: 584 VAKNAAGFASSTTELIVEAP 603
           +AKN  G AS+T +L++  P
Sbjct: 329 IAKNQFGTASTTGKLLITEP 348



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 7/109 (6%)

Query: 1950 LPTESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007
            + T+ +S+       V  PP  P  + +  +  +    SW TP  D G+P+ GY I  R 
Sbjct: 428  IDTDVESLSTSAILVVKGPPGPPDKVTVEEITDSTAQLSW-TPGRDNGSPITGYIIQART 486

Query: 2008 VTKTMWMEVGKV----DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
                 W  V  V    + N L   +  L+    Y  R+ ARN +GL EP
Sbjct: 487  PFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEP 535



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584
           S V+ EC   G P P+I+W R + I  PS   ++   + N A L I     EDAGT+ CV
Sbjct: 92  SAVKLECFALGNPVPEISWRRTSGIPFPS---KVKMKNSN-AVLEIPNFQQEDAGTYECV 147

Query: 585 AKNAAG 590
           A+N  G
Sbjct: 148 AENRRG 153



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 5/74 (6%)

Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
           +EC+  G P+P  +W +    +      Q+    DN A L I  +   D+G + CVA+N 
Sbjct: 186 WECKANGKPKPSYSWLKNGEQVAAEGRIQI----DNGA-LSIAVLNLSDSGMYQCVAENK 240

Query: 589 AGFASSTTELIVEA 602
            G   S+ +L+V A
Sbjct: 241 HGIIYSSAQLMVLA 254


>UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio
           rerio|Rep: CDNA, clone cssl:d0205 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 744

 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 80/326 (24%), Positives = 142/326 (43%), Gaps = 26/326 (7%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G ++LLEC    +P P I W  +G ++ P + + +        +   L+I NV +   G+
Sbjct: 260 GEELLLECIAAGVPTPTITWSKRGGDL-PTKKVRIG------NFDKTLRILNVSEEDIGS 312

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           YT +A NR G     + +++K      P  +E   ++++   ES  L  +  G+P+PTI 
Sbjct: 313 YTCMASNRIGSIRHTVEVQVKAA----PFWLEKPINLVLAPDESGRLVCRANGSPKPTIQ 368

Query: 768 WCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
           W  N +P++ +LP  +        I +  + +   VY   A N  G    +A ++V +  
Sbjct: 369 WLVNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLD-- 426

Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886
                P +   + Q I V E     L      +P+P + W++N           + +   
Sbjct: 427 ---MAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG 483

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946
            +E  I    +E D G Y CVAS   GK  +  +V ++V++ T +    +      G TV
Sbjct: 484 TLE--IKQAQTE-DQGTYTCVASIILGKMEN--QVRLEVKEPTRIVRAPEHKTEPRGTTV 538

Query: 947 ILECQTSHTVS----TKWYHNKKEIS 968
             +C+  H  S      W  ++K +S
Sbjct: 539 RFDCRVKHDPSLPATVTWLKDEKPLS 564



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 138/594 (23%), Positives = 227/594 (38%), Gaps = 55/594 (9%)

Query: 633  PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PPT  K+    Y VD   +I++EC     P P   W   G+      N+       M   
Sbjct: 41   PPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFF----NVGKDPRVTMRSR 96

Query: 692  CSVLKITNVKKFQ--EGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
               L+I +  K +  EG Y   A N  G A S  I+L++      P +V+EP   + VR+
Sbjct: 97   SGTLEIRSSGKPEDYEGEYQCFASNNLGTAISNKILLRVSKSPLWPKEVLEP---VTVRE 153

Query: 749  GESVILSAQ-VVGNPRPTITWCKN-NKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803
            G  ++L+     G P P   W  +   P+   + +    +GD     +L  K  K +   
Sbjct: 154  GSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVL-AKDAKTDYSC 212

Query: 804  TLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKE--KGTIKLVARVTRN 859
              + E +  I + +   T++  T  N     P F++     + K   +G   L+  +   
Sbjct: 213  NARFEFTHTIQQKNP-YTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLLECIAAG 271

Query: 860  -PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P+ITW +    +   +    NFD     L I NV SE D G Y C+ASN  G   H 
Sbjct: 272  VPTPTITWSKRGGDLPTKKVRIGNFDK---TLRILNV-SEEDIGSYTCMASNRIGSIRHT 327

Query: 919  ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM---DHREI 975
              V +        K +      +E   ++     S   + +W  N + I       +R +
Sbjct: 328  VEVQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRV 387

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFI-RKLQDFEVKE 1030
            + +                 V +C   ++      +  + V +  P  +  K Q  +V E
Sbjct: 388  LDD----TIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKNQLIKVIE 443

Query: 1031 KDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             +   LE         ++ W ++G         Y     G    L I+     D+G Y+C
Sbjct: 444  NNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG---TLEIKQAQTEDQGTYTC 500

Query: 1090 ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKDG 1143
            +        E  V   V+ P  I+   +++   +G    F+  +    +L   V W KD 
Sbjct: 501  VASIILGKMENQVRLEVKEPTRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATVTWLKDE 560

Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193
              + FS   +L  D   + L IY+ + DD G Y+C    E+     +A LTV E
Sbjct: 561  KPLSFSWIGRLKKD--DESLTIYNVNPDDGGTYTCTAKTEIDEDTASARLTVTE 612



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 136/602 (22%), Positives = 240/602 (39%), Gaps = 64/602 (10%)

Query: 709  TVVAVNREGEASLPIVL--KIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPT 765
            +++++  E  A++ + L  KI+   K+PP ++ + LK  IV   +++I+  +  GNP PT
Sbjct: 14   SIISLLSEEAAAIEVPLDPKIQQELKQPPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPT 73

Query: 766  ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKD-EGVYTLKAENSEGIAETSAVIT 821
              W +N K     K         + ++ I    K +D EG Y   A N+ G A ++ ++ 
Sbjct: 74   FQWRRNGKFFNVGKDPRVTMRSRSGTLEIRSSGKPEDYEGEYQCFASNNLGTAISNKILL 133

Query: 822  VEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETI 879
                    ++ PL+     E +TV+E   + L        P P   W   +  I P    
Sbjct: 134  ------RVSKSPLWPKEVLEPVTVREGSPLVLACNPPPGLPPPETFWM--DSFIMPIAQD 185

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVA-----SNSAGKSSHGARV----TIDVEKVTF 930
             +   G N +L  +NV ++    DY C A          K+ +  +V     I   + TF
Sbjct: 186  RRVSMGLNGDLFFSNVLAKDAKTDYSCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTF 245

Query: 931  VK--HLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988
            +    L  +     G+ ++LEC  +  V T      K    +  +++             
Sbjct: 246  LSPTGLSSTKMVLRGEELLLEC-IAAGVPTPTITWSKRGGDLPTKKVRIGNFDKTLRILN 304

Query: 989  XXXXDVGVIKCIVKDQETS---TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SET 1044
                D+G   C+  ++  S   T+ V  +  P ++ K  +  +   +   L    N S  
Sbjct: 305  VSEEDIGSYTCMASNRIGSIRHTVEVQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPK 364

Query: 1045 ADVVWERDGEIIK---PKKNKYDFEKRGHIRKLYIRNTSVHD---EGEYSCILRDESCTA 1098
              + W  +GE I+   P  N+   +       +   +++V+      E+  +L      A
Sbjct: 365  PTIQWLVNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLL----ANA 420

Query: 1099 EVTVVELPPEII-TRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQF-SNHIQLT 1155
             V+V+++ P ++  + Q  KV + N+   E         L+RWFK+G        H +L 
Sbjct: 421  FVSVLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLY 480

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211
             +G    L+I     +D G Y+C     +G  +    L V+EP+    +R PE    P  
Sbjct: 481  HNG---TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKEPT--RIVRAPEHKTEPRG 535

Query: 1212 TDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEY 1266
            T       +   P     VTW K +  +     F+ I  +KK   +L I     DD   Y
Sbjct: 536  TTVRFDCRVKHDPSLPATVTWLKDEKPL----SFSWIGRLKKDDESLTIYNVNPDDGGTY 591

Query: 1267 TC 1268
            TC
Sbjct: 592  TC 593



 Score = 67.7 bits (158), Expect = 3e-09
 Identities = 83/385 (21%), Positives = 144/385 (37%), Gaps = 28/385 (7%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXX 1540
            +EKP+ N+   P+E   L C   G P+P + W  +G+ ++++      R           
Sbjct: 339  LEKPI-NLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTIIFETV 397

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y+C A N+HG +  +  V +       +  ++   K    +   +     G P
Sbjct: 398  QFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSP 457

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
             P + W+KNG  L +  +           + IK+ +      YT  AS   G    +V L
Sbjct: 458  LPLLRWFKNG--LGSGLDGGHYRLYHNGTLEIKQAQTEDQGTYTCVASIILGKMENQVRL 515

Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720
            +V +       P    E    +V  + +    D  L  T   ++  +P +  WI    + 
Sbjct: 516  EVKEPTRIVRAPEHKTEPRGTTVRFDCRVK-HDPSLPATVTWLKDEKPLSFSWI--GRLK 572

Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
            +D E+  I  +N +    +   A+  +   E   S  + + T  D  S           D
Sbjct: 573  KDDESLTIYNVNPDDGGTYTCTAKTEI--DEDTASARLTV-TENDSSSASNRSASAGRPD 629

Query: 1781 -----------NESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKKWKXXXXXXXXXARI 1826
                         SV +TW P  +N  SP+  + V+ ++   E  KW+           +
Sbjct: 630  PPQDLELSDPSARSVRLTWVPGNEN-NSPVTHFLVQFEEDRWEPGKWQNLSIYDWNLNSV 688

Query: 1827 Q-KLSINTTYQFRIYARNEIGTSLP 1850
              +LS    YQFR+ A N +G S P
Sbjct: 689  NLQLSPFVNYQFRVIAINAVGQSQP 713



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 84/409 (20%), Positives = 152/409 (37%), Gaps = 21/409 (5%)

Query: 1278 KLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336
            K++ E+ + PP IV    ++Y +    ++ +  + +  P P  +W  N K     K  + 
Sbjct: 33   KIQQELKQ-PPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFFNVGKDPRV 91

Query: 1337 SIDSKSASLTIKKVENTD--AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-- 1392
            ++ S+S +L I+     +   G Y+    NN G A +   + +    SP     +LE   
Sbjct: 92   TMRSRSGTLEIRSSGKPEDYEGEYQCFASNNLGTA-ISNKILLRVSKSPLWPKEVLEPVT 150

Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNS 1447
              + S + +  + P         +       I     +S+    ++  +    ++ KT+ 
Sbjct: 151  VREGSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKTDY 210

Query: 1448 SYRFRAYAVNEVDISDA-SETTEYYKVIKETK--IQSPTVEKPLKNITTEPNEDIELTCI 1504
            S   R    + +   +  +   +  + I ET+    SPT     K +     E++ L CI
Sbjct: 211  SCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLR--GEELLLECI 268

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563
              GVP P +TW + G  L T K    N                 Y C+A N  G +  + 
Sbjct: 269  AAGVPTPTITWSKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMASNRIGSIRHTV 328

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             V ++  P      + I       +   +     G P P + W  NG  +E+    N   
Sbjct: 329  EVQVKAAPFWL--EKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLP-NPNR 385

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
            +     I  + ++   S+ Y   ASN  G       + V D   +  GP
Sbjct: 386  RVLDDTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGP 434



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 56/243 (23%), Positives = 102/243 (41%), Gaps = 27/243 (11%)

Query: 1252 TLIIRKCTEDDQCEYTCV--LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL-- 1307
            TL I++   +DQ  YTCV  ++  K   ++++EV E P +IV         RG+ V    
Sbjct: 484  TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKE-PTRIVRAPEHKTEPRGTTVRFDC 542

Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367
             V +         W+ + K +      +   D +  SLTI  V   D G Y    +    
Sbjct: 543  RVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDE--SLTIYNVNPDDGGTYTCTAKTEID 600

Query: 1368 HADVEMNVTILD--------------KPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
                   +T+ +              +P PP    + +  + S+ + W  P N  NS + 
Sbjct: 601  EDTASARLTVTENDSSSASNRSASAGRPDPPQDLELSDPSARSVRLTW-VPGNENNSPVT 659

Query: 1414 YYVVEYQE--IDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            +++V+++E   +  +W  +S+ +      ++Q L    +Y+FR  A+N V  S  S  + 
Sbjct: 660  HFLVQFEEDRWEPGKWQNLSIYDWNLNSVNLQ-LSPFVNYQFRVIAINAVGQSQPSHPSA 718

Query: 1470 YYK 1472
             Y+
Sbjct: 719  RYQ 721



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 50/208 (24%), Positives = 84/208 (40%), Gaps = 18/208 (8%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
           +L+  P     K +   V E +   LEC     P P + W   G        +   ++  
Sbjct: 424 VLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNG--------LGSGLDGG 475

Query: 688 MH--MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
            +   +   L+I   +   +GTYT VA    G+    + L++    KEP +++   +   
Sbjct: 476 HYRLYHNGTLEIKQAQTEDQGTYTCVASIILGKMENQVRLEV----KEPTRIVRAPEHKT 531

Query: 746 VRQGESVILSAQVVGNPR--PTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGV 802
             +G +V    +V  +P    T+TW K+ KP+  +   +   D  S+TI       D G 
Sbjct: 532 EPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNP-DDGGT 590

Query: 803 YTLKAENSEGIAETSAVITVEEPTEENA 830
           YT  A+        SA +TV E    +A
Sbjct: 591 YTCTAKTEIDEDTASARLTVTENDSSSA 618



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 5/84 (5%)

Query: 519 KHTPDGSTVQFECQVEGYPR--PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576
           K  P G+TV+F+C+V+  P     +TW +    +  S   ++  DD++   L I  V P+
Sbjct: 530 KTEPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDES---LTIYNVNPD 586

Query: 577 DAGTFTCVAKNAAGFASSTTELIV 600
           D GT+TC AK      +++  L V
Sbjct: 587 DGGTYTCTAKTEIDEDTASARLTV 610



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC   G P P ITW ++   + P++  ++   D    TL I  V  ED G++TC
Sbjct: 260 GEELLLECIAAGVPTPTITWSKRGGDL-PTKKVRIGNFDK---TLRILNVSEEDIGSYTC 315

Query: 584 VAKNAAGFASSTTELIVEA 602
           +A N  G    T E+ V+A
Sbjct: 316 MASNRIGSIRHTVEVQVKA 334



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 3/87 (3%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+E L+  +  G+P P + W K G  L   K+  I   +KT  +RI  +       YT  
Sbjct: 260  GEELLLECIAAGVPTPTITWSKRGGDLPT-KKVRIGNFDKT--LRILNVSEEDIGSYTCM 316

Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
            ASN  G+    V ++V   P   E P+
Sbjct: 317  ASNRIGSIRHTVEVQVKAAPFWLEKPI 343



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 94/475 (19%), Positives = 174/475 (36%), Gaps = 41/475 (8%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            + RG ++ L       P P   W   SK        K  I +   +L I  V   D G Y
Sbjct: 257  VLRGEELLLECIAAGVPTPTITW---SKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSY 313

Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYV 1416
                 N  G     + V +   P    KP   +L  D S   +C     N      I ++
Sbjct: 314  TCMASNRIGSIRHTVEVQVKAAPFWLEKPINLVLAPDESGRLVC---RANGSPKPTIQWL 370

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
            V  + I+++     + +       + ++  SS  ++  A NE     A+    +  V+  
Sbjct: 371  VNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLLANA---FVSVLD- 426

Query: 1477 TKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRX 1533
                +P +  P    I    N    L C F G P P + W+++G         Y   +  
Sbjct: 427  ---MAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG 483

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y C+A    G++E    + +++   I  + E   +       +   
Sbjct: 484  TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKEPTRIVRAPEHKTEPRGTTVRFDCR 543

Query: 1594 AVIEGIPPPEVIWYKNGN--------KLENDKE----YNITTKEK---TSVIRIKELKRS 1638
               +   P  V W K+          +L+ D E    YN+   +    T   + +  + +
Sbjct: 544  VKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNPDDGGTYTCTAKTEIDEDT 603

Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698
             S++ T+  ++++  S+   +    D P   E    + + S  SV + W P  ++    +
Sbjct: 604  ASARLTVTENDSSSASNRSASAGRPDPPQDLE----LSDPSARSVRLTWVPG-NENNSPV 658

Query: 1699 TKYAIEKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
            T + ++  E   +  +W  ++  D ++ +  +Q L+    Y FRVIA N VG S+
Sbjct: 659  THFLVQFEEDRWEPGKWQNLSIYDWNLNSVNLQ-LSPFVNYQFRVIAINAVGQSQ 712



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 25/106 (23%), Positives = 54/106 (50%), Gaps = 8/106 (7%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVH 1923
            P  P++  +S+ ++RSV L W  P +   SP+T+++++F+  + +   W  +     +++
Sbjct: 628  PDPPQDLELSDPSARSVRLTWV-PGNENNSPVTHFLVQFEEDRWEPGKWQNLSIYDWNLN 686

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969
               ++ +       FR+ A N VG S P+   +    ++ T  +PP
Sbjct: 687  SVNLQ-LSPFVNYQFRVIAINAVGQSQPSHPSA----RYQTSGAPP 727



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 5/75 (6%)

Query: 530 ECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
           EC   G P P + WF+           +++Y++     TL I++   ED GT+TCVA   
Sbjct: 450 ECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHN----GTLEIKQAQTEDQGTYTCVASII 505

Query: 589 AGFASSTTELIVEAP 603
            G   +   L V+ P
Sbjct: 506 LGKMENQVRLEVKEP 520



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 5/157 (3%)

Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283
            T  +TW K+   +  T+K   I +  K TL I   +E+D   YTC+  +   + +  VEV
Sbjct: 274  TPTITWSKRGGDLP-TKKVR-IGNFDK-TLRILNVSEEDIGSYTCMASNRIGSIRHTVEV 330

Query: 1284 -VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
             V+  P  ++      +       L+      P+P  +W+VN + I+      P+     
Sbjct: 331  QVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIES-SLPNPNRRVLD 389

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
             ++  + V+   + +Y+    N  G+      V++LD
Sbjct: 390  DTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLD 426


>UniRef50_P20241 Cluster: Neuroglian precursor; n=17;
            Endopterygota|Rep: Neuroglian precursor - Drosophila
            melanogaster (Fruit fly)
          Length = 1302

 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 158/795 (19%), Positives = 281/795 (35%), Gaps = 35/795 (4%)

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328
            VLLD K       +    P +     R+    RG  + L   Y   P P   W  + + I
Sbjct: 228  VLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKDGQRI 287

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKP 1387
            +           KS  L I++    DAG Y   + N  G+A    + + +   P    +P
Sbjct: 288  QWSDRITQGHYGKS--LVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEP 345

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
             I         + ++          I ++   + I+ +     + +T     I NL    
Sbjct: 346  EIATAAEDE-EVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRIINLVKGD 404

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            +  +   A N +          Y  V    + + PT+ +    ++T    ++ + C   G
Sbjct: 405  TGNYGCNATNSLGYV-------YKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKCRVNG 457

Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567
             P+P V W R    L   +   +                 Y C A N  GE++    + +
Sbjct: 458  SPKPLVKWLRASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVV 517

Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627
            ++   IT   ++ +        +      +     E+ W+K+G  ++ + +         
Sbjct: 518  KEHTRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDN 577

Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687
            S+   K ++   S +YT  A      ++    L V D P+ P+   I  +  +    I W
Sbjct: 578  SLTIAKTMELD-SGEYTCVARTRLDEATARANLIVQDVPNAPKLTGITCQADKAE--IHW 634

Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746
            +   D+    +  Y I+ +       W    +   + ++  + +++    Y FRVIA N 
Sbjct: 635  EQQGDNRS-PILHYTIQFNTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNK 693

Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVE 1805
            +G S    +      T  DVP            +  ++ I+W P  E    +P   Y V 
Sbjct: 694  IGASPP-SAHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNFHYYVS 752

Query: 1806 IKQE--GKKWKXXXXXXXXXARIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGK 1861
             K++     W+           I      T   Y  ++ A N+ G S    +++ +    
Sbjct: 753  WKRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIKVVAINDRGES-NVAAEEVVGYSG 811

Query: 1862 TLTPPSQPRNFVVSEST-SRSVTLKWTE-PESNGGSPITNYIIEFKTV-KGKSWTKIVTV 1918
               P   P NF + + T S S  + WT   E +       Y I+  T  +G+   + + V
Sbjct: 812  EDRPLDAPTNFTMRQITSSTSGYMAWTPVSEESVRGHFKGYKIQTWTENEGEEGLREIHV 871

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978
             G  H   +   K   +   RI A N  G      S  +  +    VPS P   L+   +
Sbjct: 872  KGDTHNALVTQFKPDSKNYARILAYN--GRFNGPPSAVIDFDTPEGVPS-PVQGLDAYPL 928

Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK-----VDVNTLKFNIRDLSE 2033
            GS+  M  W  P +  G  L GY I   +V ++   E  +      D    +  +  L  
Sbjct: 929  GSSAFMLHWKKPLYPNG-KLTGYKIYYEEVKESYVGERREYDPHITDPRVTRMKMAGLKP 987

Query: 2034 NHTYMIRIYARNEIG 2048
            N  Y I I A  ++G
Sbjct: 988  NSKYRISITATTKMG 1002



 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 129/589 (21%), Positives = 224/589 (38%), Gaps = 51/589 (8%)

Query: 530  ECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588
            EC+ +G P P+ +W +        + D +M        TLVI     ED G + C A N 
Sbjct: 58   ECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGR-GTLVITIPKDEDRGHYQCFASNE 116

Query: 589  AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX-XXXXADILEGIPPTFSKKPKAQYVDE 647
             G A+S +  + +A L+    E                    +G P         + +D 
Sbjct: 117  FGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQESIDG 176

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
                +   R+   PE ++ W       V  E+ S    SD +  CS   +    +++ G 
Sbjct: 177  SIKSINNSRMTLDPEGNL-WFSN----VTREDAS----SDFYYACSATSVFR-SEYKIGN 226

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIVRQGESVILSAQVVGNPRPT 765
              ++ V + G ++        +  K PP  Q +   +S+ +R G+ + L     G P P 
Sbjct: 227  KVLLDVKQMGVSA--------SQNKHPPVRQYVSRRQSLALR-GKRMELFCIYGGTPLPQ 277

Query: 766  ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
              W K+ + ++     + G      +++     D G YT    N  G A++ ++I     
Sbjct: 278  TVWSKDGQRIQWSDRITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSII----- 332

Query: 826  TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
               N+  P F    +  T  E   +    R    P P I+W  N + I  S    +    
Sbjct: 333  LNVNS-VPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVT 391

Query: 886  ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
            +N   +I  V    D+G+Y C A+NS G       + +  E  T +     +  T +G+ 
Sbjct: 392  DNTIRIINLVKG--DTGNYGCNATNSLGYVYKDVYLNVQAEPPT-ISEAPAAVSTVDGRN 448

Query: 946  VILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
            V ++C+ + +     KW      ++G   R  +Q               D G   C  ++
Sbjct: 449  VTIKCRVNGSPKPLVKWLRASNWLTG--GRYNVQAN--GDLEIQDVTFSDAGKYTCYAQN 504

Query: 1004 Q----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVV--WERDGEII 1056
            +    +    LVVKE      ++ Q++EV     A     E + +T ++   W +DG+ I
Sbjct: 505  KFGEIQADGSLVVKEH-TRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSI 563

Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTVV 1103
              +     F K      L I  T   D GEY+C+ R   +  TA   ++
Sbjct: 564  DFEAQP-RFVKTND-NSLTIAKTMELDSGEYTCVARTRLDEATARANLI 610



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 70/297 (23%), Positives = 126/297 (42%), Gaps = 23/297 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F+K+P+     E  +++ ECR   +PEP I+W+  G+ I           +D     +
Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTD-----N 393

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            ++I N+ K   G Y   A N  G     + L +   + EPP + E   ++    G +V 
Sbjct: 394 TIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNV---QAEPPTISEAPAAVSTVDGRNVT 450

Query: 754 LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
           +  +V G+P+P + W + +  +       +++GD      ++     D G YT  A+N  
Sbjct: 451 IKCRVNGSPKPLVKWLRASNWLTGGRYNVQANGDLE----IQDVTFSDAGKYTCYAQNKF 506

Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
           G  +    + V+E T    EP  +     E+   +  T +            I W+++ +
Sbjct: 507 GEIQADGSLVVKEHTRITQEPQNY-----EVAAGQSATFRCNEAHDDTLEIEIDWWKDGQ 561

Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928
            I   E   +     +  L I     E+DSG+Y CVA     +++  AR  + V+ V
Sbjct: 562 SID-FEAQPRFVKTNDNSLTIAKT-MELDSGEYTCVARTRLDEAT--ARANLIVQDV 614



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 128/605 (21%), Positives = 221/605 (36%), Gaps = 59/605 (9%)

Query: 729  TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKS--DG 784
            T +  P +++  +           I+  +  G P P  +W KN K    +A   +     
Sbjct: 32   TKQPAPGELLFKVAQQNKESDNPFIIECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQP 91

Query: 785  DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844
               ++ I  PK  +D G Y   A N  G A +++V       E NA         + +  
Sbjct: 92   GRGTLVITIPKD-EDRGHYQCFASNEFGTATSNSVYV--RKAELNAFKDEAAKTLEAVE- 147

Query: 845  KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN---FDGENIELVITNVDSEIDS 901
             E   +K  A     P P++ W     I    ++I  +    D E   L  +NV  E  S
Sbjct: 148  GEPFMLKCAAP-DGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEG-NLWFSNVTREDAS 205

Query: 902  GD-YKCVASNSAGKSSH--GARVTIDVEKVTFV----KHLQ-KSYETEE------GKTVI 947
             D Y   ++ S  +S +  G +V +DV+++       KH   + Y +        GK + 
Sbjct: 206  SDFYYACSATSVFRSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRME 265

Query: 948  LECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-- 1003
            L C    T    T W  + + I   D   I Q               D G   C V +  
Sbjct: 266  LFCIYGGTPLPQTVWSKDGQRIQWSDR--ITQGHYGKSLVIRQTNFDDAGTYTCDVSNGV 323

Query: 1004 --QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKK 1060
               ++ ++++   ++P F ++ +     E +  + E          + W  +G+ I+  +
Sbjct: 324  GNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIE--Q 381

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEIITRLQNQ 1116
            +  +  +      + I N    D G Y C   +          + V   PP I       
Sbjct: 382  STPNPRRTVTDNTIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAV 441

Query: 1117 KVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
                G   T +  +      LV+W +  + +    +  +  +G    L+I D    DAG+
Sbjct: 442  STVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRY-NVQANGD---LEIQDVTFSDAGK 497

Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT--W 1229
            Y+C    + G  +    L V+E +   T     + +    +  +   E  D+TL++   W
Sbjct: 498  YTCYAQNKFGEIQADGSLVVKEHT-RITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDW 556

Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVE 1285
            +K    I D E           +L I K  E D  EYTCV    L +A +   L V+ V 
Sbjct: 557  WKDGQSI-DFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVP 615

Query: 1286 FPPKI 1290
              PK+
Sbjct: 616  NAPKL 620



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 57/263 (21%), Positives = 104/263 (39%), Gaps = 19/263 (7%)

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEP 1194
            W KDG  IQ+S+ I     GK   L I   + DDAG Y+C+    VGN++  +I+ +   
Sbjct: 280  WSKDGQRIQWSDRITQGHYGKS--LVIRQTNFDDAGTYTCDVSNGVGNAQSFSII-LNVN 336

Query: 1195 SINFTLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251
            S+ +  + PE      + +         +P+    ++W      IE +        V   
Sbjct: 337  SVPYFTKEPEIATAAEDEEVVFECRAAGVPEP--KISWIHNGKPIEQSTP-NPRRTVTDN 393

Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309
            T+ I    + D   Y C   ++       + + V   PP I +         G +VT+  
Sbjct: 394  TIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKC 453

Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369
                 P+P  +W+  S  +   ++   +    +  L I+ V  +DAG Y    +N  G  
Sbjct: 454  RVNGSPKPLVKWLRASNWLTGGRYNVQA----NGDLEIQDVTFSDAGKYTCYAQNKFGEI 509

Query: 1370 DVEMNVTILDKPSPPGKPNILEI 1392
              + ++ + +      +P   E+
Sbjct: 510  QADGSLVVKEHTRITQEPQNYEV 532



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 21/198 (10%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PPT S+ P A    +G ++ ++CR+   P+P + WL +    +     +V    D     
Sbjct: 431 PPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWL-RASNWLTGGRYNVQANGD----- 484

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
             L+I +V     G YT  A N+ GE  A   +V+K  T   + PQ  E      V  G+
Sbjct: 485 --LEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEHTRITQEPQNYE------VAAGQ 536

Query: 751 SVILSAQVVGNP--RPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806
           S         +      I W K+ + +  +A P     + +S+TI K  ++ D G YT  
Sbjct: 537 SATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMEL-DSGEYTCV 595

Query: 807 AENSEGIAETSAVITVEE 824
           A      A   A + V++
Sbjct: 596 ARTRLDEATARANLIVQD 613



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 5/96 (5%)

Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565
           Q+  P   E      T DG  V  +C+V G P+P + W R +  +   +     Y+    
Sbjct: 428 QAEPPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGR-----YNVQAN 482

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
             L I++V   DAG +TC A+N  G   +   L+V+
Sbjct: 483 GDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVK 518



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 2/93 (2%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F ++       +   V FEC+  G P P+I+W      I+ S         DN  T+ 
Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDN--TIR 396

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602
           I  +   D G + C A N+ G+      L V+A
Sbjct: 397 IINLVKGDTGNYGCNATNSLGYVYKDVYLNVQA 429



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF-QMYYDDDNVATLVIREVFPEDAGTFT 582
           G  ++  C   G P PQ  W +    I+ S    Q +Y      +LVIR+   +DAGT+T
Sbjct: 261 GKRMELFCIYGGTPLPQTVWSKDGQRIQWSDRITQGHYGK----SLVIRQTNFDDAGTYT 316

Query: 583 CVAKNAAGFASS 594
           C   N  G A S
Sbjct: 317 CDVSNGVGNAQS 328


>UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep:
           NRCAM protein - Homo sapiens (Human)
          Length = 771

 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 114/478 (23%), Positives = 194/478 (40%), Gaps = 48/478 (10%)

Query: 507 SMAPIFV-EKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKP-SQDFQMYYDDD 563
           S +P++  EKL P     G ++   C+   G P P I W   +    P S+      + D
Sbjct: 136 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD 195

Query: 564 NVATLVIREVFPEDAGT-FTCVAK-NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
               L    V PED    + C A+ N          + V+    D  ++ T+        
Sbjct: 196 ----LYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND-TIAANLSDTE 250

Query: 622 XXXXADILEGIPPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                   E  PPTF + +  A   +E  G+ + LEC    +P P I W  K + ++P +
Sbjct: 251 FYGAKSSRER-PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA-KEDGMLP-K 307

Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
           N +V    +       L+I +V +   G Y  +A N  G     I +++K      P  I
Sbjct: 308 NRTVYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA----PYWI 358

Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKP 794
              +++++  GE   L  +  GNP+P I+W  N  P++  P     K DGDT    I   
Sbjct: 359 TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT---IIFSN 415

Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLV 853
            + +   VY   A N  G    +A + V       AEPP  +     +  V       L 
Sbjct: 416 VQERSSAVYQCNASNEYGYLLANAFVNV------LAEPPRILTPANTLYQVIANRPALLD 469

Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                +P+P+I W++  +  +  E I    +   +E+ +   DS   +G Y CVA N  G
Sbjct: 470 CAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDS---TGTYTCVARNKLG 526

Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH----TVSTKWYHNKKEI 967
            + +   V ++++  T++    +    + G  V  EC+  H    +++  W  + +E+
Sbjct: 527 MAKN--EVHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 582



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 132/623 (21%), Positives = 249/623 (39%), Gaps = 71/623 (11%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PPT +++ PK   +D   +I+++C     P P  +W   G     D++  V ++      
Sbjct: 39   PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 98

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               +      +  EG Y   A N  G A S  IV++     + P    E L+ + ++ G+
Sbjct: 99   IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKEKLEPITLQSGQ 155

Query: 751  SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803
            S++L  +  +G P P I W  N+   + LP         +GD +   +L P+  +++ + 
Sbjct: 156  SLVLPCRPPIGLPPPIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 212

Query: 804  TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843
              +  +++ I +    +  VI+V+E           TE          PP F+      +
Sbjct: 213  YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNAS 272

Query: 844  VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             KE  +G +  +  +    P P I W + + ++  + T+ +NF+ + ++++     SE D
Sbjct: 273  NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-KTLQIIHV---SEAD 328

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
            SG+Y+C+A N+ G   H   V +                  E  T+I     +      W
Sbjct: 329  SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388

Query: 961  YHN--KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014
              N    EI+  D    I +G                V +C   ++      +  + V  
Sbjct: 389  LTNGVPIEIAPDDPSRKI-DGDTIIFSNVQERSS--AVYQCNASNEYGYLLANAFVNVLA 445

Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
              P  +      ++V     A+L+     S    + W +  +     ++ Y   + G   
Sbjct: 446  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--- 502

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPE--IITRLQNQKVNKGNKATFEIE 1129
             L I        G Y+C+ R++   A+  V +E+     I+ + +   V +G+  +FE +
Sbjct: 503  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECK 562

Query: 1130 LTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--- 1183
            +     L   V W KD  E+      + T+D  K  L + D   DD+G Y+C    +   
Sbjct: 563  VKHDHTLSLTVLWLKDNRELPSDE--RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDS 618

Query: 1184 -KCTAILT-VEEPSINFTLRLPE 1204
               +A+L+ V+ P+  F L L +
Sbjct: 619  VSASAVLSVVDVPNPPFDLELTD 641



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 95/423 (22%), Positives = 171/423 (40%), Gaps = 41/423 (9%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXX 1545
            +N+   P ED  L C   G P+P+++W  +G  ++ A      +                
Sbjct: 362  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSS 421

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y+C A N++G +  +  V +  +P   ++  +   +       L+     G P P + 
Sbjct: 422  AVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIE 481

Query: 1606 WYK--NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            W+K   G+ L  D    I    +   + I   ++  +  YT  A N  G +  EV L++ 
Sbjct: 482  WFKGAKGSALHED----IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 537

Query: 1664 DKP---SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVAD 1718
            D      +PE  V+ R      V+ E K    D  L LT   ++ +   P + R+     
Sbjct: 538  DATWIVKQPEYAVVQR---GSMVSFECKVK-HDHTLSLTVLWLKDNRELPSDERF----T 589

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778
            VD+D     +  ++++    +  +A   +   +++ +  ++  + +DVP+          
Sbjct: 590  VDKD--HLVVADVSDDDSGTYTCVANTTL---DSVSASAVL--SVVDVPNPPFDLELTDQ 642

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARIQ-KLSINTT 1834
            +D +SV ++W P + N  SPI  + +E +    K   W             Q KLS    
Sbjct: 643  LD-KSVQLSWTPGDDN-NSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVN 700

Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----E 1890
            Y FR+ A N IG SLP  + ++  + K   P   P       S   ++ + W +P    E
Sbjct: 701  YSFRVMAVNSIGKSLPSEASEQY-LTKASEPDKNPTAVEGLGSEPDNLVITW-KPLNGFE 758

Query: 1891 SNG 1893
            SNG
Sbjct: 759  SNG 761



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 108/467 (23%), Positives = 183/467 (39%), Gaps = 41/467 (8%)

Query: 1044 TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            T  + W ++  ++   +  Y +FEK      L I + S  D G Y CI ++       T+
Sbjct: 293  TPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNALGAIHHTI 347

Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFS-NHIQLTI 1156
               V+  P  IT  QN  ++ G   T  I    G+   R  W  +G  I+ + +     I
Sbjct: 348  SVRVKAAPYWITAPQNLVLSPGEDGTL-ICRANGNPKPRISWLTNGVPIEIAPDDPSRKI 406

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
            DG    +   +     +  Y C   N     +       +N  L  P  IL PANT  Y 
Sbjct: 407  DG--DTIIFSNVQERSSAVYQCNASNEYGYLLANA---FVN-VLAEPPRILTPANT-LYQ 459

Query: 1217 TVEIPDETLDVTWYKKK-SVIE---DTEKFTLISDV----KKRTLIIRKCTEDDQCEYTC 1268
             +      LD  ++      IE     +   L  D+    +  TL I    +D    YTC
Sbjct: 460  VIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 519

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            V  +     K +V +       +  + EY + +RGS    +V ++   + +D  +  + +
Sbjct: 520  VARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGS----MVSFECKVK-HDHTLSLTVL 574

Query: 1328 IKKCKHTKPSIDSKSAS---LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384
              K     PS +  +     L +  V + D+G Y                ++++D P+PP
Sbjct: 575  WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPP 634

Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQ- 1441
                + +    S+ + W  P +  NS I  +++EY++       W     ++ TQT+ Q 
Sbjct: 635  FDLELTDQLDKSVQLSW-TPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL 693

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488
             L    +Y FR  AVN +  S  SE +E Y        ++PT  + L
Sbjct: 694  KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGL 740



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 12/290 (4%)

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            PP  P I  +D+S   +   E  + G +  +Y+     E    ++I       TQT IQ 
Sbjct: 168  PP--PIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQ 224

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDI 1499
             +  S        +N+   ++ S+T E+Y   K ++ + PT   P  N + +       +
Sbjct: 225  KQPISVKVISVDELNDTIAANLSDT-EFYGA-KSSRERPPTFLTPEGNASNKEELRGNVL 282

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
             L CI  G+P P + W ++   L   +  Y+N                 Y+CIA N  G 
Sbjct: 283  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 342

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
            +  +  V ++  P    + +++      G++  +     G P P + W  NG  +E   +
Sbjct: 343  IHHTISVRVKAAPYWITAPQNLVL--SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 400

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
             + + K     I    ++   S+ Y   ASN  G       + V  +P +
Sbjct: 401  -DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPR 449



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 4/122 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923
            P+ P +  +++   +SV L WT P  +  SPIT +IIE++    K   W     V G+  
Sbjct: 631  PNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 689

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
               ++ +       FR+ A N++G SLP+E+    L K +     PTA   +     N+V
Sbjct: 690  TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 748

Query: 1984 MT 1985
            +T
Sbjct: 749  IT 750



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 8/92 (8%)

Query: 524 GSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           GS V FEC+V+      +T  W +    +   + F +  D D+   LV+ +V  +D+GT+
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDH---LVVADVSDDDSGTY 608

Query: 582 TCVAKNAAGFASSTTEL-IVEAPLSDHGSEMT 612
           TCVA       S++  L +V+ P      E+T
Sbjct: 609 TCVANTTLDSVSASAVLSVVDVPNPPFDLELT 640


>UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5
            precursor; n=12; Amniota|Rep:
            Matrix-remodeling-associated protein 5 precursor - Homo
            sapiens (Human)
          Length = 2828

 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 179/935 (19%), Positives = 341/935 (36%), Gaps = 72/935 (7%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            P   +K P+   V   +D +  C     P+P + W       +   N    I+    +  
Sbjct: 1853 PQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPN--TRIQRFEVLKN 1910

Query: 693  SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
              L I  V+    G Y   A N  G   + ++L +    ++P  +    + + V  G+++
Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTV--QQPQILASHYQDVTVYLGDTI 1968

Query: 753  ILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808
             +     G P P I+W   ++ V     P +S    H    L  K+    D GVY   A 
Sbjct: 1969 AMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVAS 2028

Query: 809  NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
            N+ G    +  + V         P +   + + I++    +I +       P+PS+ W  
Sbjct: 2029 NAAGADSLAIRLHVAA-----LPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVL 2083

Query: 869  NNEI-ISPSETITQN-FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-- 924
             +   I PS+ +  N F   N  L I N+  + DSG Y+CVA+N  G +    ++ +   
Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPK-DSGRYECVAANLVGSARRTVQLNVQRA 2142

Query: 925  VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--W-YHNKKEISGM-DHREIIQEGR 980
                       +  +   G T+ L+C  S     +  W   +K+ I  +      I+   
Sbjct: 2143 AANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFA 2202

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK------DVA 1034
                        D G   C+ +++     +V+K  +     K++  E  +       D+ 
Sbjct: 2203 NGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLK 2262

Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRG------HIRKLYIRNTSVHDEGEY 1087
            +  V       ++ W   DG ++       D   R       +   LY     + +EG+Y
Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDY 2322

Query: 1088 SCILRD----ESCTAEVTVVELPPEIITRLQ-NQKVNKGNKATFEIELTKGDAL--VRWF 1140
            +C   +    +     V VV  P  I  +     +V  G+  T   E  KG+ +  V W 
Sbjct: 2323 TCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACE-AKGEPMPKVTWL 2381

Query: 1141 KDGSEI--QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAI-LTVE 1192
               +++    S   Q+  DG    L I      D+G Y+C V NS     K   I + V+
Sbjct: 2382 SPTNKVIPTSSEKYQIYQDG---TLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQ 2438

Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKF-TLISDV 1248
             P IN        +   A   +   ++   E   T  V W   + V+     +   I+  
Sbjct: 2439 PPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVH 2498

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP--KIVDYE---REYRIKRGS 1303
               +L IR   + D  +  C+  +     +L +++    P  K + ++    +     G 
Sbjct: 2499 GNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGH 2558

Query: 1304 DVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362
             ++L       P P+  W++ N   ++  +  +         L I  + + DAG Y+   
Sbjct: 2559 TISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVA 2618

Query: 1363 ENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
             N  GH +  +++ +  KP    +  N++ I +         P   G     + +     
Sbjct: 2619 RNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMH 2678

Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQ 1480
            ++  +  ++  ++        ++  S +    Y    E +   +  +     +    +I 
Sbjct: 2679 LEGPQ--TLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRIT 2736

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515
            S    +P   I T P   ++L C+  G+P+  +TW
Sbjct: 2737 S----EPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 171/830 (20%), Positives = 297/830 (35%), Gaps = 85/830 (10%)

Query: 599  IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKKPKAQYVDEGSDILLECRL 657
            I EA  SD G    V               +  +PP    +K +   +  G  I + C  
Sbjct: 2012 IKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTA 2071

Query: 658  VAIPEPDIAWLF-KGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGTYTVVAVNR 715
             A P P + W+   G +I P +     +  ++ ++ +  L I N+     G Y  VA N 
Sbjct: 2072 KAAPLPSVRWVLGDGTQIRPSQ----FLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANL 2127

Query: 716  EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKP 774
             G A   + L ++             +   VR G ++ L     G+P P I W   + + 
Sbjct: 2128 VGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRM 2187

Query: 775  VKAL---PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
            + AL    ++     +   ++K    KD G Y   A N  G  +   V+ V+   +    
Sbjct: 2188 IDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVG--DDYVVLKVDVVMK---- 2241

Query: 832  PPLFINRFQEITVKE--KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
             P  I   +E   K    G +K+    T  P P I+W   +  +  S   + +  G    
Sbjct: 2242 -PAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKR 2300

Query: 890  LVITNVDS----EI---DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942
             V+ N  +    E+   + GDY C A N  GK     RV +     T       + +   
Sbjct: 2301 YVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPY 2360

Query: 943  GKTVILECQTSHTVSTK--WYH--NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998
            G  V + C+       K  W    NK   +  +  +I Q+G             D G   
Sbjct: 2361 GDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDG---TLLIQKAQRSDSGNYT 2417

Query: 999  CIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVA------ILEVEINS-ETADVV 1048
            C+V++   ++  T+ +     P  I    +     +++A      +++ +     T  V+
Sbjct: 2418 CLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVL 2477

Query: 1049 WERDGEIIKPKK---NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVT 1101
            W     ++ P     N+      G    L IR+    D  +  C+ R+E   A    ++T
Sbjct: 2478 WAFPEGVVLPAPYYGNRITVHGNG---SLDIRSLRKSDSVQLVCMARNEGGEARLILQLT 2534

Query: 1102 VVE-LPPEIITRLQNQKVNKGNKATFEIEL----TKGDALVRWFKDGSEIQFSNHIQLTI 1156
            V+E +   I     ++K+      T  +      T   +LV    +G+++Q    +Q   
Sbjct: 2535 VLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFY 2594

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPAN 1211
                  L I      DAG Y C   N+     +  ++    +P  N   +    + +   
Sbjct: 2595 HKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEAN--KQYHNLVSIING 2652

Query: 1212 TDAYLTVEIPDETLD-VTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
                L    P       +W     + +E  +    +S +   TL +R+ +  D+  Y C 
Sbjct: 2653 ETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 2712

Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSK 1326
            +      S T + V V+ +PP+I          R G+ V L       P+ +  W +  K
Sbjct: 2713 METEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDK 2772

Query: 1327 IIKKCKHTKPSIDSK---------SASLTIKKVENTDAGIYKLRLENNCG 1367
                  H K  + ++           SLTI+     DAG YK   +N  G
Sbjct: 2773 -----SHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILG 2817



 Score = 74.5 bits (175), Expect = 3e-11
 Identities = 154/761 (20%), Positives = 275/761 (36%), Gaps = 84/761 (11%)

Query: 511  IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLV 569
            I  EKL     P G ++   C  +  P P + W       I+PSQ            TL 
Sbjct: 2049 IHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLY 2108

Query: 570  IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629
            IR + P+D+G + CVA N  G A  T +L V+   ++                       
Sbjct: 2109 IRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAAN----------------------- 2145

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
              I  T  ++   +Y   G  + L+C     P P I W    + ++   +   + +S + 
Sbjct: 2146 ARITGTSPRRTDVRY---GGTLKLDCSASGDPWPRILWRLPSKRMI---DALFSFDSRIK 2199

Query: 690  MYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            ++ +  L + +V     G Y  VA N+ G+    +VLK+    K      +      V  
Sbjct: 2200 VFANGTLVVKSVTDKDAGDYLCVARNKVGDDY--VVLKVDVVMKPAKIEHKEENDHKVFY 2257

Query: 749  GESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSD--GDTHSITI-------LKPKKVK 798
            G  + +     G P P I+W   +   V +     D  G T    +            ++
Sbjct: 2258 GGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMR 2317

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            +EG YT  AEN  G  E    + V       A   +    +  + V     + +      
Sbjct: 2318 EEGDYTCFAENQVGKDEMRVRVKV-----VTAPATIRNKTYLAVQVPYGDVVTVACEAKG 2372

Query: 859  NPVPSITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
             P+P +TW    N++I  S    Q +  ++  L+I       DSG+Y C+  NSAG+   
Sbjct: 2373 EPMPKVTWLSPTNKVIPTSSEKYQIY--QDGTLLIQKAQRS-DSGNYTCLVRNSAGEDRK 2429

Query: 918  GARVTIDVEKVTFVKHLQKSYETEE----GKTVILECQTS--HTVSTKWYHNKKEISGMD 971
               + ++V+      +        E    G   +++C+     T    W   +  +    
Sbjct: 2430 TVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAP 2489

Query: 972  H--REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK-LQDFEV 1028
            +    I   G              V ++ C+ +++     L+++ T+ E + K +    +
Sbjct: 2490 YYGNRITVHGNGSLDIRSLRKSDSVQLV-CMARNEGGEARLILQLTVLEPMEKPIFHDPI 2548

Query: 1029 KEKDVAIL--EVEIN-----SETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080
             EK  A+    + +N     + T  +VW   +G  ++  +    F  +     L+I   S
Sbjct: 2549 SEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD-GMLHISGLS 2607

Query: 1081 VHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT---KGD 1134
              D G Y C+ R+ +   E  V   V L PE   +  N  V+  N  T ++  T    G 
Sbjct: 2608 SVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHN-LVSIINGETLKLPCTPPGAGQ 2666

Query: 1135 ALVRW-FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193
                W   +G  ++    +          L + +  + D G Y C +      ++ ++  
Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726

Query: 1194 PSINFTLRL-----PEFILVPANTDAYLTVEIPDETLDVTW 1229
              I +  R+     P     P NT     + +     D+TW
Sbjct: 2727 IVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767



 Score = 73.7 bits (173), Expect = 5e-11
 Identities = 136/660 (20%), Positives = 247/660 (37%), Gaps = 46/660 (6%)

Query: 1072 RKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATF 1126
            R L I+  S  D G Y C+  +    +S    + V  LPP I   +L+N  +  G   + 
Sbjct: 2008 RTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPG--LSI 2065

Query: 1127 EIELTKGDA---LVRW-FKDGSEIQFSNHIQLTIDG-KKQKLKIYDCDLDDAGEYSCE-- 1179
             I  T   A    VRW   DG++I+ S  +   +       L I +    D+G Y C   
Sbjct: 2066 HIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAA 2125

Query: 1180 --VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP---DETLDVTW-YKKK 1233
              VG+++ T  L V+  + N  +               L ++     D    + W    K
Sbjct: 2126 NLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSK 2185

Query: 1234 SVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKI 1290
             +I+    F + I      TL+++  T+ D  +Y CV  +        LKV+VV  P KI
Sbjct: 2186 RMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKI 2245

Query: 1291 VDYER-EYRIKRGSDVTLLVDYQAFPQPNDEW------IVNSKIIKKCK--HTKPSIDSK 1341
               E  ++++  G D+ +       P P   W      +VNS +        TK  +   
Sbjct: 2246 EHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFN 2305

Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401
            + +L   +V   + G Y    EN  G  ++ + V ++  P+       L +     ++  
Sbjct: 2306 NGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVT 2365

Query: 1402 DEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460
               E  G     + ++    ++  T     +        IQ  + + S  +     N   
Sbjct: 2366 VACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSA- 2424

Query: 1461 ISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRD 1518
              +  +T   +  ++  KI  +P     ++ I    +  + + C   G+P P+V W + +
Sbjct: 2425 -GEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKL-IDCKAEGIPTPRVLWAFPE 2482

Query: 1519 GKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
            G  L       + T                     C+A N+ GE      + + +     
Sbjct: 2483 GVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKP 2542

Query: 1575 ISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLENDKEYNITTKEKTSVIR 1631
            I ++ I +K     G    +     G P P ++W   NG  L++ ++      +   ++ 
Sbjct: 2543 IFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLH 2602

Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREISRESVTIEWKPP 1690
            I  L    +  Y   A N AG +   V+LKV  KP +  +   ++  I+ E++ +   PP
Sbjct: 2603 ISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPP 2662



 Score = 69.7 bits (163), Expect = 8e-10
 Identities = 99/504 (19%), Positives = 186/504 (36%), Gaps = 36/504 (7%)

Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKS--VIEDTEKFTLISDV 1248
            E+P I    + P+ + V A TD     E   +    VTW K  +  ++    +      +
Sbjct: 1851 EKPQI--LTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVL 1908

Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV---EVVEFPPKIVDYEREYRIKRGSDV 1305
            K  TL+IRK    D+ +Y C   +     ++ V     V+ P  +  + ++  +  G  +
Sbjct: 1909 KNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTI 1968

Query: 1306 TLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLE 1363
             +    +  P P   WI  + ++ +     +  I   ++ +L+IK+   +D G+YK    
Sbjct: 1969 AMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVAS 2028

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEID---SSSINI-CWDEPENTGNSTIIYYVVEY 1419
            N  G   + + + +   P    +  +  I      SI+I C    +     ++ + + + 
Sbjct: 2029 NAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHC--TAKAAPLPSVRWVLGDG 2086

Query: 1420 QEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477
             +I  ++++  ++         I+NL    S R+   A N V  +  +      +     
Sbjct: 2087 TQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANA 2146

Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR----- 1532
            +I   T   P +         ++L C   G P P++ W    K++  A  ++++R     
Sbjct: 2147 RI---TGTSP-RRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFA 2202

Query: 1533 -XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C+A N  G+      V +  KP      E+   K   G +  
Sbjct: 2203 NGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLK 2262

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLEN----DKEYNITTKE----KTSVIRIKELKRSHSSKY 1643
            V  V  G+P PE+ W      L N      +    TK         +   E+       Y
Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDY 2322

Query: 1644 TIEASNTAGTSSVEVTLKVYDKPS 1667
            T  A N  G   + V +KV   P+
Sbjct: 2323 TCFAENQVGKDEMRVRVKVVTAPA 2346



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 57/240 (23%), Positives = 102/240 (42%), Gaps = 21/240 (8%)

Query: 733  EPPQVIEPLKSMIVRQGES-VILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTH 787
            E PQ++      +    E+  +   +  G P+P +TW K +      P     + +   +
Sbjct: 1851 EKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN 1910

Query: 788  SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847
               +++  +V+D G Y   A N  G+     +++V        +P +  + +Q++TV   
Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTV-----QQPQILASHYQDVTVYLG 1965

Query: 848  GTIKLVARVTRNPVPSITWY----RNNEIISPSET-ITQNFDGENIELVITNVDSEIDSG 902
             TI +       P P I+W     R  + +SP E+ IT +   EN  L I    S  D G
Sbjct: 1966 DTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLH---ENRTLSIKEA-SFSDRG 2021

Query: 903  DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKW 960
             YKCVASN+AG  S   R+ +        +   ++     G ++ + C  + +   S +W
Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRW 2081



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 149/672 (22%), Positives = 238/672 (35%), Gaps = 63/672 (9%)

Query: 1047 VVWER--DGEIIKPKKNKYDFE--KRGHIRKLYIRNTSVHDEGEYSCILR-----DESCT 1097
            V W +   G ++ P      FE  K G    L IR   V D G+Y C        D    
Sbjct: 1885 VTWTKVSTGALMTPNTRIQRFEVLKNG---TLVIRKVQVQDRGQYMCTASNLHGLDRMVV 1941

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRW-FKDGSEIQFSNHIQL 1154
                 V+ P  + +  Q+  V  G+    E  L KG     + W F D    Q  + ++ 
Sbjct: 1942 LLSVTVQQPQILASHYQDVTVYLGDTIAMEC-LAKGTPAPQISWIFPDRRVWQTVSPVES 2000

Query: 1155 TID-GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE-----PSINFTLRLPEFILV 1208
             I   + + L I +    D G Y C   N+     L +       P +    +L E I +
Sbjct: 2001 RITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKL-ENISL 2059

Query: 1209 PANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCE 1265
            P     ++        L  V W           +F    +      TL IR     D   
Sbjct: 2060 PPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGR 2119

Query: 1266 YTCVLLD----AKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDE 1320
            Y CV  +    A+ T +L V+      +I     R   ++ G  + L       P P   
Sbjct: 2120 YECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRIL 2179

Query: 1321 WIVNSKIIKKCKHTKPSIDSK-----SASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
            W + SK +        S DS+     + +L +K V + DAG Y     N  G   V + V
Sbjct: 2180 WRLPSKRMIDALF---SFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKV 2236

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435
             ++ K   P K    E +   +    D   +   + +    + +   D +    V +  +
Sbjct: 2237 DVVMK---PAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGS---LVNSFMQ 2290

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK--VIK-ETKIQSPTVEKP--LKN 1490
            +  S    K    +       NEV + +  + T + +  V K E +++   V  P  ++N
Sbjct: 2291 SDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRN 2350

Query: 1491 IT----TEPNEDI-ELTCIFGGVPQPKVTWYRDGKK-LKTAKATYE--NRXXXXXXXXXX 1542
             T      P  D+  + C   G P PKVTW     K + T+   Y+              
Sbjct: 2351 KTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQR 2410

Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKHKV---GDEWLVTAVIEG 1598
                 Y C+  N  GE   +  + +  Q P I  +   I    ++   G   L+    EG
Sbjct: 2411 SDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEG 2470

Query: 1599 IPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            IP P V+W +  G  L      N  T      + I+ L++S S +    A N  G + + 
Sbjct: 2471 IPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLI 2530

Query: 1658 VTLKVYDKPSKP 1669
            + L V +   KP
Sbjct: 2531 LQLTVLEPMEKP 2542



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 109/493 (22%), Positives = 186/493 (37%), Gaps = 69/493 (13%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            + +E +YT + + ++ +  D++ V  K  +   + A I  +       P G  V   C+ 
Sbjct: 2316 MREEGDYTCFAENQVGK--DEMRVRVKVVT---APATIRNKTYLAVQVPYGDVVTVACEA 2370

Query: 534  EGYPRPQITWFRQTAIIKP--SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
            +G P P++TW   T  + P  S+ +Q+Y D     TL+I++    D+G +TC+ +N+AG 
Sbjct: 2371 KGEPMPKVTWLSPTNKVIPTSSEKYQIYQD----GTLLIQKAQRSDSGNYTCLVRNSAGE 2426

Query: 592  ASSTT--ELIVEAP-LSDHGSEMTVXXXXXXXXXXXXADI-LEGIPPTFSKKPKAQYV-D 646
               T    + V+ P ++ + + +T              D   EGIP      P+  +   
Sbjct: 2427 DRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIP-----TPRVLWAFP 2481

Query: 647  EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706
            EG         V +P P     + G  I    N S+ I S             ++K    
Sbjct: 2482 EG---------VVLPAP-----YYGNRITVHGNGSLDIRS-------------LRKSDSV 2514

Query: 707  TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVILSAQVVGNPRPT 765
                +A N  GEA L + L +     E P   +P+   I    G ++ L+    G P P+
Sbjct: 2515 QLVCMARNEGGEARLILQLTV-LEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPS 2573

Query: 766  ITW-------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818
            + W        ++ + ++    K+DG  H    +      D G Y   A N+ G  E   
Sbjct: 2574 LVWVLPNGTDLQSGQQLQRFYHKADGMLH----ISGLSSVDAGAYRCVARNAAGHTERLV 2629

Query: 819  VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSE 877
             + V    E N +   + N    +++    T+KL            +W   N + +   +
Sbjct: 2630 SLKVGLKPEANKQ---YHNL---VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQ 2683

Query: 878  TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937
            T+ +    +N  L +    S  D G Y C      G S     V +              
Sbjct: 2684 TLGRVSLLDNGTLTVREA-SVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPV 2742

Query: 938  YETEEGKTVILEC 950
              T  G TV L C
Sbjct: 2743 IYTRPGNTVKLNC 2755



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 63/288 (21%), Positives = 113/288 (39%), Gaps = 20/288 (6%)

Query: 831  EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNEIISPSETITQNFDG-EN 887
            +P +     Q ++V  +         T  P P +TW +     +++P+  I Q F+  +N
Sbjct: 1852 KPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRI-QRFEVLKN 1910

Query: 888  IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947
              LVI  V  + D G Y C ASN  G       +++ V++   +    +      G T+ 
Sbjct: 1911 GTLVIRKVQVQ-DRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIA 1969

Query: 948  LECQTSHTVSTK--WYHNKKE----ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001
            +EC    T + +  W    +     +S ++ R  + E R            D GV KC+ 
Sbjct: 1970 MECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENR--TLSIKEASFSDRGVYKCVA 2027

Query: 1002 KDQETSTMLVVK---ETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWE-RDGE 1054
             +   +  L ++     +P  I + +   +       + +   ++ A    V W   DG 
Sbjct: 2028 SNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGT 2087

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
             I+P +  +          LYIRN +  D G Y C+  +   +A  TV
Sbjct: 2088 QIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTV 2135



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 65/278 (23%), Positives = 104/278 (37%), Gaps = 23/278 (8%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
            G  I L C     P P + W+        D      ++   H    +L I+ +     G 
Sbjct: 2557 GHTISLNCSAAGTPTPSLVWVLPNGT---DLQSGQQLQRFYHKADGMLHISGLSSVDAGA 2613

Query: 708  YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
            Y  VA N  G     + LK+   + E  +    L S+I   GE++ L     G  +   +
Sbjct: 2614 YRCVARNAAGHTERLVSLKVGL-KPEANKQYHNLVSII--NGETLKLPCTPPGAGQGRFS 2670

Query: 768  WCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-VITV 822
            W   N    +  + L   S  D  ++T+ +   V D G Y  + E   G + TS  VI +
Sbjct: 2671 WTLPNGMHLEGPQTLGRVSLLDNGTLTV-REASVFDRGTYVCRMETEYGPSVTSIPVIVI 2729

Query: 823  EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
              P    +EP         I  +   T+KL       P   ITW   ++    +    + 
Sbjct: 2730 AYPPRITSEPT------PVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARL 2783

Query: 883  FDGENIE----LVITNVDSEIDSGDYKCVASNSAGKSS 916
            +    +     L I +  ++ D+G YKC+A N  G  S
Sbjct: 2784 YGNRFLHPQGSLTIQHA-TQRDAGFYKCMAKNILGSDS 2820



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 524  GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582
            G T+  EC  +G P PQI+W F    + +     +         TL I+E    D G + 
Sbjct: 1965 GDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYK 2024

Query: 583  CVAKNAAGFASSTTELIVEA 602
            CVA NAAG  S    L V A
Sbjct: 2025 CVASNAAGADSLAIRLHVAA 2044



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 8/99 (8%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578
            T +  TV F C+  G P+P +TW + +  A++ P+   Q +    N  TLVIR+V  +D 
Sbjct: 1866 TAETDTV-FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN-GTLVIRKVQVQDR 1923

Query: 579  GTFTCVAKNAAGFASSTT--ELIVEAP--LSDHGSEMTV 613
            G + C A N  G         + V+ P  L+ H  ++TV
Sbjct: 1924 GQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTV 1962



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 8/130 (6%)

Query: 474  LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533
            + D   Y   ++ +    +  +PV         +  P  V   RP     G+TV+  C  
Sbjct: 2703 VFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRP-----GNTVKLNCMA 2757

Query: 534  EGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPEDAGTFTCVAKNAAG 590
             G P+  ITW     + +K     ++Y +       +L I+     DAG + C+AKN  G
Sbjct: 2758 MGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILG 2817

Query: 591  FASSTTELIV 600
              S TT + V
Sbjct: 2818 SDSKTTYIHV 2827



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 58/241 (24%), Positives = 92/241 (38%), Gaps = 28/241 (11%)

Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK-KLKTAKATYEN-----RXXXXXXX 1539
            K  + ++     D    C   G P+P VTW +     L T     +              
Sbjct: 1858 KSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRK 1917

Query: 1540 XXXXXXXXYKCIAFNDHG--EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
                    Y C A N HG   +     V +QQ  ++    +D+     +GD   +  + +
Sbjct: 1918 VQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVY--LGDTIAMECLAK 1975

Query: 1598 GIPPPEVIWYKNGNKL---ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            G P P++ W     ++    +  E  IT  E  + + IKE   S    Y   ASN AG  
Sbjct: 1976 GTPAPQISWIFPDRRVWQTVSPVESRITLHENRT-LSIKEASFSDRGVYKCVASNAAGAD 2034

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP-DNNRW 1713
            S+ + L V   P     PVI +E   E++++   PP    GL +  +   K  P  + RW
Sbjct: 2035 SLAIRLHVAALP-----PVIHQE-KLENISL---PP----GLSIHIHCTAKAAPLPSVRW 2081

Query: 1714 I 1714
            +
Sbjct: 2082 V 2082



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 51/220 (23%), Positives = 91/220 (41%), Gaps = 22/220 (10%)

Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-----LKI 697
           Q V EG    L C + A   P I W      ++PD +I  A   D     S+     L+I
Sbjct: 489 QTVLEGGPCQLSCNVKASESPSIFW------VLPDGSILKAPMDDPDSKFSILSSGWLRI 542

Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757
            +++    G Y  +A  R+    +   + +++   +P +  +   ++    GESV L   
Sbjct: 543 KSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAE--KDTVTIGKNPGESVTLPCN 600

Query: 758 VVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814
            +  P   ++W   N+ +      T       + T+  PK +V D G Y   A N +G  
Sbjct: 601 ALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGAD 660

Query: 815 ETSAVITVEE-----PTEENAEP-PLFINRFQEITVKEKG 848
             +  ITV +     P++    P    ++R +E  V+++G
Sbjct: 661 HFTVGITVTKKGSGLPSKRGRRPGAKALSRVREDIVEDEG 700



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 38/155 (24%), Positives = 69/155 (44%), Gaps = 8/155 (5%)

Query: 1233 KSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291
            K+ ++D + KF+++S    R   I+     D   Y C+        ++   V+   P   
Sbjct: 522  KAPMDDPDSKFSILSSGWLR---IKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQ 578

Query: 1292 DYERE-YRIKR--GSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTI 1347
              E++   I +  G  VTL  +  A P+ +  WI+ N +II    +T       + +L+I
Sbjct: 579  PAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSI 638

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382
             KV+ +D+G Y+    N  G     + +T+  K S
Sbjct: 639  PKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGS 673


>UniRef50_UPI000155E24A Cluster: PREDICTED: similar to myosin binding
            protein H-like; n=4; Eutheria|Rep: PREDICTED: similar to
            myosin binding protein H-like - Equus caballus
          Length = 507

 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 63/290 (21%), Positives = 127/290 (43%), Gaps = 19/290 (6%)

Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356
            Y  K G  V LL+ +Q  P+P   W  +   +   + +  +   + + L I++ +  D+G
Sbjct: 63   YIRKVGDTVNLLIPFQGKPKPRATWTCDGCALDASRVSVRN-GERDSILFIREAQRADSG 121

Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
             Y+L ++     A   +++ ++++P PP    ++++  S+  + W  P++TGN  ++ Y 
Sbjct: 122  RYQLSVQLGELEATATIDILVIERPGPPQSIKLVDVWGSNAILEWTPPQDTGNVALLGYT 181

Query: 1417 VEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVI 1474
            V+  +  +  W +V +   +T  ++  L   +SY FR +A N+  +S+ +  T +   + 
Sbjct: 182  VQKADTKSGLWFTVLERYHRTSCTVSKLIVGNSYAFRVFAENQCGLSETAPITADLAHIQ 241

Query: 1475 KETKI------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522
            K   +            ++P   +PL + TT    D +L C     P+PK+ W ++   +
Sbjct: 242  KAATVYKTEGFAQRDFSEAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDI 301

Query: 1523 ----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568
                K    T+                  Y C A N  GE    C V ++
Sbjct: 302  QGNPKYRALTHLGICSLEIRKPGPFDRGIYTCKAVNPLGEASVDCRVDVK 351



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 45/168 (26%), Positives = 82/168 (48%), Gaps = 5/168 (2%)

Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644
            KVGD   +    +G P P   W  +G  L+  +  ++   E+ S++ I+E +R+ S +Y 
Sbjct: 66   KVGDTVNLLIPFQGKPKPRATWTCDGCALDASR-VSVRNGERDSILFIREAQRADSGRYQ 124

Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704
            +        ++  + + V ++P  P+  + + ++   +  +EW PP D G + L  Y ++
Sbjct: 125  LSVQLGELEATATIDILVIERPGPPQS-IKLVDVWGSNAILEWTPPQDTGNVALLGYTVQ 183

Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSE 1751
            K +  +  W  V  ++R   T C + KL     Y FRV A+N  G SE
Sbjct: 184  KADTKSGLWFTV--LERYHRTSCTVSKLIVGNSYAFRVFAENQCGLSE 229



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 11/134 (8%)

Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-------PSPPTAPLEIRMVGSNIVM 1984
            E+D I+F   A+           Q   LE  AT+       P PP +   + + GSN ++
Sbjct: 105  ERDSILFIREAQRADSGRYQLSVQLGELEATATIDILVIERPGPPQSIKLVDVWGSNAIL 164

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
              W  P+  G   LLGY +   D    +W  V +   +     +  L   ++Y  R++A 
Sbjct: 165  -EWTPPQDTGNVALLGYTVQKADTKSGLWFTVLE-RYHRTSCTVSKLIVGNSYAFRVFAE 222

Query: 2045 NEIGLSE--PLESD 2056
            N+ GLSE  P+ +D
Sbjct: 223  NQCGLSETAPITAD 236



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 1/87 (1%)

Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566
           S AP F + L    T  G   Q  C V   P+P+I W +    I+ +  ++       + 
Sbjct: 258 SEAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDIQGNPKYRA-LTHLGIC 316

Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFAS 593
           +L IR+  P D G +TC A N  G AS
Sbjct: 317 SLEIRKPGPFDRGIYTCKAVNPLGEAS 343



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH----S 788
           E P+  +PL       G    L   V  +P+P I W KN   ++  P K    TH    S
Sbjct: 259 EAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDIQGNP-KYRALTHLGICS 317

Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823
           + I KP    D G+YT KA N  G A     + V+
Sbjct: 318 LEIRKPGPF-DRGIYTCKAVNPLGEASVDCRVDVK 351



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 7/104 (6%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE- 1924
            P  P++  + +    +  L+WT P+  G   +  Y ++    K   W    TV    H  
Sbjct: 146  PGPPQSIKLVDVWGSNAILEWTPPQDTGNVALLGYTVQKADTKSGLW---FTVLERYHRT 202

Query: 1925 HC-IENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATV 1965
             C +  +   +   FR+ AEN  G+S   P  +    ++K ATV
Sbjct: 203  SCTVSKLIVGNSYAFRVFAENQCGLSETAPITADLAHIQKAATV 246


>UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin light
            chain kinase; n=1; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to myosin light chain kinase -
            Strongylocentrotus purpuratus
          Length = 1627

 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 8/238 (3%)

Query: 493  DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
            D+ P +  P   EQ+  P F +K +     DG  V  E  + G     + W R    I  
Sbjct: 1071 DEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVD 1130

Query: 553  SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSE 610
             ++F+ Y    N+  L I E+FPED+G +TC A N  G +  +  + V  E  +S   S+
Sbjct: 1131 CKEFR-YVSRGNIYQLEIAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQ 1189

Query: 611  -MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669
             M V                + IPP F ++P++Q V+EG+  +  C +   P P + W  
Sbjct: 1190 SMDVDVSLSTDMPCTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSK 1249

Query: 670  KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
             G         S+  +   H     L+I N +    G Y   A N EGE      L I
Sbjct: 1250 DGRPFTDGGRFSIRSDKFTH----TLEIQNARSTDAGVYACTARNSEGEVVCEFTLDI 1303



 Score = 87.8 bits (208), Expect = 3e-15
 Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 9/220 (4%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-L 1345
            PPK +   +E       +V L    Q  P P  +W V++K I+  K    ++D+   S L
Sbjct: 1375 PPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSRL 1434

Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK----PSPPGKPNILEIDSSSINICW 1401
            TI +    D+G+Y+    N+ G A     + +  K     +P GKP + +   +S  I W
Sbjct: 1435 TISEAFAEDSGVYRCEATNSSGTASTSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITW 1494

Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461
              P   G S I  Y V+ ++   T W  V N+T+T   +  +     Y +R  A NE   
Sbjct: 1495 AAPAEDGGSPIFNYKVDGRKAKETGWTEVANVTQTSFEVTGIVPGVEYVYRVSAENEAGW 1554

Query: 1462 SDASETTEYYKVIKETKI---QSPTVEKPLKNITTEPNED 1498
            S ++  ++   VI E++     S + +KP     + PN+D
Sbjct: 1555 SPSTAISD-RAVITESESPPKTSSSTDKPPVVKDSPPNKD 1593



 Score = 86.6 bits (205), Expect = 7e-15
 Identities = 52/184 (28%), Positives = 90/184 (48%), Gaps = 6/184 (3%)

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIE 1646
            DE ++   ++G+P P V W+ +  ++E+DK   IT   +  S + I E     S  Y  E
Sbjct: 1391 DEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCE 1450

Query: 1647 ASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
            A+N++GT+S    L V  K   P  P G   + + S+ S  I W  P +DGG  +  Y +
Sbjct: 1451 ATNSSGTASTSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKV 1510

Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763
            +  +     W +VA+V +   ++ +  +    EY++RV A+N  G+S +       + T 
Sbjct: 1511 DGRKAKETGWTEVANVTQ--TSFEVTGIVPGVEYVYRVSAENEAGWSPSTAISDRAVITE 1568

Query: 1764 LDVP 1767
             + P
Sbjct: 1569 SESP 1572



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 67/258 (25%), Positives = 107/258 (41%), Gaps = 23/258 (8%)

Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536
           E    + ++   +E++      E   S  +   P F   LR K   DG   +  C V+G 
Sbjct: 513 EGGSARSMESSEDERVVSRSKIEPVRSGSRVQLPFFSLPLRRKTVYDGEPARISCNVQGT 572

Query: 537 PRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596
           P+P+I+W +    I     + + Y    VA + IR     D GTF C AKNA G A+S  
Sbjct: 573 PKPKISWSKNGVPIYDGTFYNITYRW-GVAMVEIRHASKSDTGTFRCTAKNAEGEATSAC 631

Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656
           EL+VE  +    +E                   + I P+F+K  +     EG  + LE +
Sbjct: 632 ELVVEQRVPRSETE-------------------DYIRPSFAKPLRRIRAKEGRKVRLEIQ 672

Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716
           ++  PEP + WL    ++V  +++ V            L I  V     G Y  +A +  
Sbjct: 673 VMGWPEPKVTWLKDNVDVVHSDHMYV---EKFPNGLQSLVIYRVVPTDAGRYQAIASSPA 729

Query: 717 GEASLPIVLKIKTGEKEP 734
           G+A+    + +  GE  P
Sbjct: 730 GKATCSADVDVIPGEALP 747



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 20/197 (10%)

Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-------- 791
           PL+   V  GE   +S  V G P+P I+W KN  P+       DG  ++IT         
Sbjct: 551 PLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIY------DGTFYNITYRWGVAMVE 604

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE--PTEENAE--PPLFINRFQEITVKEK 847
           ++     D G +   A+N+EG A ++  + VE+  P  E  +   P F    + I  KE 
Sbjct: 605 IRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIRAKEG 664

Query: 848 GTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
             ++L  +V   P P +TW ++N +++       + F      LVI  V    D+G Y+ 
Sbjct: 665 RKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRV-VPTDAGRYQA 723

Query: 907 VASNSAGKSSHGARVTI 923
           +AS+ AGK++  A V +
Sbjct: 724 IASSPAGKATCSADVDV 740



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 33/99 (33%), Positives = 54/99 (54%)

Query: 502  TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561
            T  ++   P F+  L+ ++  +   V  EC V+G P P + WF     I+  +   +  D
Sbjct: 1368 TDSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMD 1427

Query: 562  DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
            +D V+ L I E F ED+G + C A N++G AS++ EL+V
Sbjct: 1428 NDGVSRLTISEAFAEDSGVYRCEATNSSGTASTSGELMV 1466



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 59/210 (28%), Positives = 89/210 (42%), Gaps = 31/210 (14%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790
            PP   +  + M +R GE V+L   + G+    + W +N + +   K     S G+ + + 
Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLE 1146

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITV-EEPT----------------------- 826
            I +    +D G YT +A N  G +E SA+ITV EEP+                       
Sbjct: 1147 IAEIFP-EDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMPCTA 1205

Query: 827  --EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884
              +E+  PP F    Q   V+E  T      V  +PVPS+TW ++    +     +   D
Sbjct: 1206 TMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSIRSD 1265

Query: 885  GENIELVITNVDSEIDSGDYKCVASNSAGK 914
                 L I N  S  D+G Y C A NS G+
Sbjct: 1266 KFTHTLEIQNARS-TDAGVYACTARNSEGE 1294



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 37/212 (17%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP+F KK +   + +G  ++LE  +      D+ WL  G++IV  +        +++   
Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQ-- 1144

Query: 693  SVLKITNVKKFQEGTYT--------------VVAVNREGEASLPIVLKIK---------- 728
              L+I  +     G YT              ++ VN E   S+ I   +           
Sbjct: 1145 --LEIAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMP 1202

Query: 729  ---TGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPT 780
               T +++  PP+  E  +S +V +G + + +  V G+P P++TW K+ +P         
Sbjct: 1203 CTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSI 1262

Query: 781  KSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
            +SD  TH++ I   +   D GVY   A NSEG
Sbjct: 1263 RSDKFTHTLEIQNARST-DAGVYACTARNSEG 1293



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 54/200 (27%), Positives = 84/200 (42%), Gaps = 16/200 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P FS   + + V +G    + C +   P+P I+W   G  I      ++     + M   
Sbjct: 546 PFFSLPLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIYDGTFYNITYRWGVAM--- 602

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEAS----LPIVLKIKTGEKEP---PQVIEPLKSMIV 746
            ++I +  K   GT+   A N EGEA+    L +  ++   E E    P   +PL+ +  
Sbjct: 603 -VEIRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIRA 661

Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802
           ++G  V L  QV+G P P +TW K+N  V         K      S+ I +     D G 
Sbjct: 662 KEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRVVPT-DAGR 720

Query: 803 YTLKAENSEGIAETSAVITV 822
           Y   A +  G A  SA + V
Sbjct: 721 YQAIASSPAGKATCSADVDV 740



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 36/114 (31%), Positives = 57/114 (50%), Gaps = 3/114 (2%)

Query: 501 PTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559
           P SE E  + P F + LR     +G  V+ E QV G+P P++TW +    +  S    + 
Sbjct: 640 PRSETEDYIRPSFAKPLRRIRAKEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVE 699

Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--SSTTELIVEAPLSDHGSEM 611
              + + +LVI  V P DAG +  +A + AG A  S+  ++I    L D G ++
Sbjct: 700 KFPNGLQSLVIYRVVPTDAGRYQAIASSPAGKATCSADVDVIPGEALPDRGGDV 753



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 4/116 (3%)

Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896
            +R  A N  GT+   TS + +  GK + P +      V +++  S  + W  P  +GGSP
Sbjct: 1447 YRCEATNSSGTAS--TSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSP 1504

Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
            I NY ++ +  K   WT++  V  +  E  +  I    E ++R+SAEN  G S  T
Sbjct: 1505 IFNYKVDGRKAKETGWTEVANVTQTSFE--VTGIVPGVEYVYRVSAENEAGWSPST 1558



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 32/133 (24%), Positives = 68/133 (51%), Gaps = 6/133 (4%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP    + Q+  +  G +   E+ +T    + V W ++G +I      +    G   +L+
Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLE 1146

Query: 1165 IYDCDLDDAGEYSCEV----GNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVE 1219
            I +   +D+G+Y+CE     G S+C+A++TV EEPS++ ++     + V  +TD   T  
Sbjct: 1147 IAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMPCTAT 1206

Query: 1220 IPDETLDVTWYKK 1232
            + ++ +   ++++
Sbjct: 1207 MDEDHIPPEFFEE 1219



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 4/155 (2%)

Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955
            P   + +  K ++   +  I      V    I     +D  ++R  A N+ G +  + S 
Sbjct: 1405 PTVKWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCEATNSSGTA--STSG 1462

Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015
             + +     VP  P    ++          +W  P  DGG+P+  Y +  R   +T W E
Sbjct: 1463 ELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTE 1522

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050
            V   +V    F +  +     Y+ R+ A NE G S
Sbjct: 1523 V--ANVTQTSFEVTGIVPGVEYVYRVSAENEAGWS 1555



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 3/153 (1%)

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVT 857
            DE      A ++ G+A          P E E A PP F  +FQ++++++   + L   +T
Sbjct: 1053 DEFTMRTYAPSATGVAADDEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVVIT 1112

Query: 858  RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
             +    + W RN + I   +       G   +L I  +  E DSG Y C A N  G+S  
Sbjct: 1113 GSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPE-DSGKYTCEALNDHGESEC 1171

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
             A +T++ E    +  + +S + +   +  + C
Sbjct: 1172 SAMITVNEEPSVSIS-ISQSMDVDVSLSTDMPC 1203



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 6/108 (5%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075
            P F +K QD  +++ +  +LEV I  S   DV W R+G+ I   K ++ +  RG+I +L 
Sbjct: 1088 PSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCK-EFRYVSRGNIYQLE 1146

Query: 1076 IRNTSVHDEGEYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVN 1119
            I      D G+Y+C  L D     C+A +TV E P   I+  Q+  V+
Sbjct: 1147 IAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVD 1194



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 2/110 (1%)

Query: 815  ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874
            E++  ++  +   +   PP F+   QE    E+  + L   V   P+P++ W+ +N+ I 
Sbjct: 1358 ESTTGVSGSDTDSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIE 1417

Query: 875  PSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              + +    D + +  L I+   +E DSG Y+C A+NS+G +S    + +
Sbjct: 1418 SDKFVVITMDNDGVSRLTISEAFAE-DSGVYRCEATNSSGTASTSGELMV 1466



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 56/242 (23%), Positives = 97/242 (40%), Gaps = 11/242 (4%)

Query: 627  DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
            D  EG PP F +  + +Y  E  +++LEC +  +P P + W    +EI  D+ + + +++
Sbjct: 1369 DSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDN 1428

Query: 687  DMHMYCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLK 742
            D      V ++T  + F E  G Y   A N  G AS    L +  G+   P+    +P  
Sbjct: 1429 D-----GVSRLTISEAFAEDSGVYRCEATNSSGTASTSGELMV-AGKVVVPKAPGGKPKV 1482

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEG 801
                +    +  +A       P   +  + +  K    T+    T +   +       E 
Sbjct: 1483 EQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTEVANVTQTSFEVTGIVPGVEY 1542

Query: 802  VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
            VY + AEN  G + ++A+      TE  + P    +  +   VK+    K  A     P 
Sbjct: 1543 VYRVSAENEAGWSPSTAISDRAVITESESPPKTSSSTDKPPVVKDSPPNKDQAGKGPGPK 1602

Query: 862  PS 863
            PS
Sbjct: 1603 PS 1604



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 42/208 (20%), Positives = 85/208 (40%), Gaps = 14/208 (6%)

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-NR 1532
            +++Q P    PL+  T    E   ++C   G P+PK++W ++G  +        TY    
Sbjct: 541  SRVQLPFFSLPLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIYDGTFYNITYRWGV 600

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ---------K 1583
                           ++C A N  GE  ++C + ++Q+   + + + I+          +
Sbjct: 601  AMVEIRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIR 660

Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
             K G +  +   + G P P+V W K N + + +D  Y          + I  +  + + +
Sbjct: 661  AKEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRVVPTDAGR 720

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPE 1670
            Y   AS+ AG ++    + V    + P+
Sbjct: 721  YQAIASSPAGKATCSADVDVIPGEALPD 748



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 31/136 (22%), Positives = 58/136 (42%), Gaps = 4/136 (2%)

Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504
            ++  +  R YA +   ++   E  EY    +  +   P+ +K  ++++    E + L  +
Sbjct: 1051 SDDEFTMRTYAPSATGVAADDEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVV 1110

Query: 1505 FGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXX---XXXYKCIAFNDHGEVE 1560
              G     V W R+G+ +   K   Y +R                  Y C A NDHGE E
Sbjct: 1111 ITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPEDSGKYTCEALNDHGESE 1170

Query: 1561 TSCVVGIQQKPVITIS 1576
             S ++ + ++P ++IS
Sbjct: 1171 CSAMITVNEEPSVSIS 1186



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 25/81 (30%), Positives = 40/81 (49%)

Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            G+  ++  VI G  P +V W +NG  + + KE+   ++     + I E+    S KYT E
Sbjct: 1102 GERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPEDSGKYTCE 1161

Query: 1647 ASNTAGTSSVEVTLKVYDKPS 1667
            A N  G S     + V ++PS
Sbjct: 1162 ALNDHGESECSAMITVNEEPS 1182



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 3/94 (3%)

Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSN 1150
            D  CTA +    +PPE     Q+Q V +G  A F  ++  GD +  + W KDG       
Sbjct: 1200 DMPCTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDV-DGDPVPSLTWSKDGRPFTDGG 1258

Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
               +  D     L+I +    DAG Y+C   NS+
Sbjct: 1259 RFSIRSDKFTHTLEIQNARSTDAGVYACTARNSE 1292



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 42/194 (21%), Positives = 76/194 (39%), Gaps = 9/194 (4%)

Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759
            K+ +   E ++++++ +   +  V    I +       ++R  A N  G   A  S  ++
Sbjct: 1408 KWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCEATNSSG--TASTSGELM 1465

Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX 1818
            +   + VP               S  ITW    ++GGSPI +YKV+  K +   W     
Sbjct: 1466 VAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTEVAN 1525

Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878
                   +  +     Y +R+ A NE G S      D+  I ++ +PP        S ST
Sbjct: 1526 VTQTSFEVTGIVPGVEYVYRVSAENEAGWSPSTAISDRAVITESESPPK------TSSST 1579

Query: 1879 SRSVTLKWTEPESN 1892
             +   +K + P  +
Sbjct: 1580 DKPPVVKDSPPNKD 1593



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK-QK 1162
            PP+ +  LQ +   + ++   E  + +G  +  V+WF    EI+    + +T+D     +
Sbjct: 1375 PPKFLRGLQEEYAWEEDEVVLECHV-QGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSR 1433

Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA 1187
            L I +   +D+G Y CE  NS  TA
Sbjct: 1434 LTISEAFAEDSGVYRCEATNSSGTA 1458



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 14/188 (7%)

Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
           V  EG      E+SE     S        +    + P F    +  TV +    ++   V
Sbjct: 510 VDSEGGSARSMESSEDERVVSRSKIEPVRSGSRVQLPFFSLPLRRKTVYDGEPARISCNV 569

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              P P I+W +N   I         +    + +V     S+ D+G ++C A N+ G+++
Sbjct: 570 QGTPKPKISWSKNGVPIYDGTFYNITYRW-GVAMVEIRHASKSDTGTFRCTAKNAEGEAT 628

Query: 917 HGARVTI----------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNK 964
               + +          D  + +F K L++    +EG+ V LE Q       K  W  + 
Sbjct: 629 SACELVVEQRVPRSETEDYIRPSFAKPLRR-IRAKEGRKVRLEIQVMGWPEPKVTWLKDN 687

Query: 965 KEISGMDH 972
            ++   DH
Sbjct: 688 VDVVHSDH 695



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 2/110 (1%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+  +  +   ++ G+      D    P P+  W  + +            D  + +L 
Sbjct: 1213 PPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSIRSDKFTHTLE 1272

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396
            I+   +TDAG+Y     N+ G    E  + IL  P+      I   D SS
Sbjct: 1273 IQNARSTDAGVYACTARNSEGEVVCEFTLDIL--PTGADDKGITASDVSS 1320


>UniRef50_A4AI84 Cluster: Serine protease, subtilase family protein;
            n=1; marine actinobacterium PHSC20C1|Rep: Serine
            protease, subtilase family protein - marine
            actinobacterium PHSC20C1
          Length = 1226

 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 94/422 (22%), Positives = 156/422 (36%), Gaps = 25/422 (5%)

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE-SVTIEWKPPLD 1692
            ++ ++ S   T  A   +  S    +     KP+  + P     ++R  SV + W  P  
Sbjct: 509  DVGKTISITVTANAQGFSTLSKTSTSTATVTKPALTQ-PQTFGVVARPGSVDLSWTEPAS 567

Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             GG  ++ Y I+      + +    D V  D+ T  +  L     Y  +V A+    F  
Sbjct: 568  FGGT-ISDYVIQYRPTSTSTYTTYNDGVSADL-TATLAGLKFGSSYYVKVAAKTE--FGT 623

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEG 1810
               + P+++KT    PS              SV + W  PS  NGG+ I DY V  +  G
Sbjct: 624  GTSTSPVLVKTLTGRPSAPTGLLATAA--PRSVSLDWLTPSTSNGGT-ISDYTVRYRLSG 680

Query: 1811 KK-WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867
               WK           A +  LS +  Y+F + A+ + G+    T       G    P  
Sbjct: 681  TTTWKTFTDGVSTDTTATVTGLSGSRKYEFAVSAKTQFGSGSSATVARSTPSGVASAPTG 740

Query: 1868 QPRNFVVSESTSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926
                 +V   +  S+ L W  P + NGG  +T+Y I ++T    +WT +V    +   H 
Sbjct: 741  -----LVGTPSLTSMELTWNSPSTTNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHT 795

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986
            I  +       F I+A+   G      S  +     + + S P +    R   +  +  +
Sbjct: 796  ISGLTRNKSYEFAIAAKTVFGTG---SSAVLAKSTQSGIASAPKSLTATR--AATTLSLN 850

Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046
            W  P    G  +  Y +  R    T W              I  L+ + +Y + +YAR  
Sbjct: 851  WTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTL 910

Query: 2047 IG 2048
             G
Sbjct: 911  AG 912



 Score = 94.3 bits (224), Expect = 3e-17
 Identities = 96/421 (22%), Positives = 150/421 (35%), Gaps = 20/421 (4%)

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK--PSKPEGPVIMREISRESVTIEWKPP-L 1691
            L  S   ++ + A    G+ S     +       S P G  ++   S  S+ + W  P  
Sbjct: 702  LSGSRKYEFAVSAKTQFGSGSSATVARSTPSGVASAPTG--LVGTPSLTSMELTWNSPST 759

Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751
             +GG  +T Y+I         W  V D       + I  L  N  Y F + A+   G   
Sbjct: 760  TNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHTISGLTRNKSYEFAIAAKTVFGTGS 819

Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811
               S  +   T   + S              S+  T  PS  NGG+ I DY V  +  G 
Sbjct: 820  ---SAVLAKSTQSGIASAPKSLTATRAATTLSLNWT-APSTTNGGT-ITDYIVRYRVAGT 874

Query: 1812 K-WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868
              WK           A I  L+ + +Y   +YAR   GT+    S   +         S 
Sbjct: 875  TTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTLAGTTALSGSSTTLRTSTPSGVASA 934

Query: 1869 PRNFVVSESTSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927
            P   V + S + S+ L W  P + NGG  +T+Y I ++T    +WT +V    +   H I
Sbjct: 935  PTGLVGTPSLT-SMELTWNSPSTTNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHTI 993

Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
              +       F I+A+   G      S  +     + + S P +    R   +  +  +W
Sbjct: 994  SGLTRNKSYEFAIAAKTVFGTG---SSAVLAKSTQSGIASAPKSLTATR--AATTLSLNW 1048

Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047
              P    G  +  Y +  R    T W              I  L+ + +Y + +YAR   
Sbjct: 1049 TAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTLA 1108

Query: 2048 G 2048
            G
Sbjct: 1109 G 1109



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451
            ++++++ W  P  T   TI  Y+V Y+   TT W +  +   T T  +I  L  + SY  
Sbjct: 844  ATTLSLNWTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDV 903

Query: 1452 RAYA 1455
              YA
Sbjct: 904  NVYA 907



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%)

Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451
            ++++++ W  P  T   TI  Y+V Y+   TT W +  +   T T  +I  L  + SY  
Sbjct: 1041 ATTLSLNWTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDV 1100

Query: 1452 RAYA 1455
              YA
Sbjct: 1101 NVYA 1104


>UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin
           1,; n=1; Danio rerio|Rep: PREDICTED: similar to
           hemicentin 1, - Danio rerio
          Length = 413

 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 87/324 (26%), Positives = 133/324 (41%), Gaps = 26/324 (8%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP+ S   +   V  G D  LEC+    P P + W  KG+    D   +   E D+H   
Sbjct: 95  PPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQ-KGDL---DLGTAPFAEQDVHR-- 148

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
             L+I  V++   G YT VA N  G +S  +VL++       P   E    +    G+++
Sbjct: 149 GTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAA----PTFSESPVDITASVGDNI 204

Query: 753 ILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH---SITILKPKKVKDEGVYTLKAE 808
            L     G P P++ W + + +P+    +   G +        ++   V DEGVY  +A+
Sbjct: 205 TLPCIARGFPTPSLIWRRQDGRPIFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAK 264

Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITWY 867
           N  G  +  A +TV        EPPL +     IT      + L  R+    P+P   W 
Sbjct: 265 NQFGSIKALARVTV-----TGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWT 319

Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
            N + +     +    DG    L +     E D+G Y C A N AG  S    VT++V  
Sbjct: 320 HNGKQVRVGGRVFLRSDG---SLHVDRAVPE-DAGTYVCTAVNVAG--SANITVTVEVHA 373

Query: 928 VTFVKHLQKSYETEEGKTVILECQ 951
              +K     Y   EG  + L C+
Sbjct: 374 PPDIKAGPLHYTASEGTPISLSCE 397



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 84/340 (24%), Positives = 129/340 (37%), Gaps = 26/340 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P+    P+ Q    G+++ + C     P P + W      +     +S++ ES M     
Sbjct: 6   PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSIS-ESGM----- 59

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            L I        G YT +A N  G AS      +     EPP +    + ++V  GE   
Sbjct: 60  -LTIRGAAPEDSGNYTCLATNEVGTAS----QSVNVNYAEPPSISVVQQMVMVVAGEDAS 114

Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEG 812
           L  Q  G P P + W K +  +   P  ++ D H  T+ ++  +  D G YT  A N  G
Sbjct: 115 LECQASGTPSPIVKWQKGDLDLGTAPF-AEQDVHRGTLQIRGVQELDSGDYTCVASNIAG 173

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-- 870
              +SAV+ ++         P F     +IT      I L       P PS+ W R +  
Sbjct: 174 --SSSAVVVLQV-----GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGR 226

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930
            I   S          +  L I +V  + D G Y C A N  G     ARVT+   +   
Sbjct: 227 PIFGKSSGHVGTSQLPSGALQIQSVWVD-DEGVYLCEAKNQFGSIKALARVTVTGLEPPL 285

Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTK---WYHNKKEI 967
           +     S  T   + + L C+    +      W HN K++
Sbjct: 286 LVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQV 325



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 61/244 (25%), Positives = 96/244 (39%), Gaps = 19/244 (7%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           G  PTFS+ P       G +I L C     P P + W  + ++  P    S        +
Sbjct: 184 GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIW--RRQDGRPIFGKSSGHVGTSQL 241

Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               L+I +V    EG Y   A N+ G  S+  + ++     EPP +++   S+     +
Sbjct: 242 PSGALQIQSVWVDDEGVYLCEAKNQFG--SIKALARVTVTGLEPPLLVQGAPSITTMIAQ 299

Query: 751 SVILSAQVV-GNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK 806
            + L  +++ G P P   W  N K V+    +  +SDG  H +    P   +D G Y   
Sbjct: 300 PLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLH-VDRAVP---EDAGTYVCT 355

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
           A N  G A  +  + V  P +  A P          T  E   I L       P P+I+W
Sbjct: 356 AVNVAGSANITVTVEVHAPPDIKAGP-------LHYTASEGTPISLSCEARGVPKPTISW 408

Query: 867 YRNN 870
            + +
Sbjct: 409 SKQH 412



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 59/218 (27%), Positives = 83/218 (38%), Gaps = 13/218 (5%)

Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792
           E P V+   ++     G  V +S    G+P P + W   N  +      S  ++  +TI 
Sbjct: 4   EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSISESGMLTI- 62

Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852
           +    +D G YT  A N  G A  S  +         AEPP      Q + V       L
Sbjct: 63  RGAAPEDSGNYTCLATNEVGTASQSVNVNY-------AEPPSISVVQQMVMVVAGEDASL 115

Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
             + +  P P + W + +  +  +    Q  D     L I  V  E+DSGDY CVASN A
Sbjct: 116 ECQASGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGTLQIRGVQ-ELDSGDYTCVASNIA 172

Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
           G SS  A V + V                 G  + L C
Sbjct: 173 GSSS--AVVVLQVGAAPTFSESPVDITASVGDNITLPC 208



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 81/393 (20%), Positives = 145/393 (36%), Gaps = 23/393 (5%)

Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347
            P +V   +      G++V +       P P   W   +  +    H + SI S+S  LTI
Sbjct: 6    PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSN--HHRMSI-SESGMLTI 62

Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407
            +     D+G Y     N  G A   +NV   + PS      ++ + +        +   T
Sbjct: 63   RGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASGT 122

Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467
              S I+ +     ++ T  +   +++ +    I+ ++   S  +   A N    S A   
Sbjct: 123  P-SPIVKWQKGDLDLGTAPFAE-QDVHRGTLQIRGVQELDSGDYTCVASNIAGSSSA--- 177

Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAK 1526
                 V+      +PT  +   +IT    ++I L CI  G P P + W R DG+ +    
Sbjct: 178  -----VVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKS 232

Query: 1527 ATYENRXXXXXXXXXXXXX-----XXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDI 1580
            + +                       Y C A N  G ++    V +   +P + +     
Sbjct: 233  SGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPS 292

Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640
                      L   +++GIP PE IW  NG ++       + +     V R        +
Sbjct: 293  ITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVP---EDA 349

Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673
              Y   A N AG++++ VT++V+  P    GP+
Sbjct: 350  GTYVCTAVNVAGSANITVTVEVHAPPDIKAGPL 382



 Score = 56.8 bits (131), Expect = 6e-06
 Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 5/208 (2%)

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXX 1537
            +++P+V    +  +     ++ ++C   G P PKV W      L    + +         
Sbjct: 3    LEAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSISESGMLTI 62

Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597
                      Y C+A N+ G    S  V   + P I++  + +      G++  +     
Sbjct: 63   RGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVV--AGEDASLECQAS 120

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            G P P V W K    L             T  ++I+ ++   S  YT  ASN AG+SS  
Sbjct: 121  GTPSPIVKWQKGDLDLGTAPFAEQDVHRGT--LQIRGVQELDSGDYTCVASNIAGSSSAV 178

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTI 1685
            V L+V   P+  E PV +     +++T+
Sbjct: 179  VVLQVGAAPTFSESPVDITASVGDNITL 206



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 68/363 (18%), Positives = 128/363 (35%), Gaps = 19/363 (5%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
            L IR    +D   YTC+  +   T    V V    PP I   ++   +  G D +L    
Sbjct: 60   LTIRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQA 119

Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371
               P P  +W      +      +   D    +L I+ V+  D+G Y     N  G +  
Sbjct: 120  SGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGTLQIRGVQELDSGDYTCVASNIAGSSSA 177

Query: 1372 EMNVTILDKPSPPGKP-NILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEI--DTTEW 1427
             + + +   P+    P +I      +I + C      T   ++I+   + + I   ++  
Sbjct: 178  VVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPT--PSLIWRRQDGRPIFGKSSGH 235

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487
            +    +      IQ++  +    +   A N+     A         +  T ++ P + + 
Sbjct: 236  VGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALAR------VTVTGLEPPLLVQG 289

Query: 1488 LKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXXX 1545
              +ITT   + + L C +  G+P P+  W  +GK+++     +  +              
Sbjct: 290  APSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVPEDA 349

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y C A N  G    +  V +   P   I    +      G    ++    G+P P + 
Sbjct: 350  GTYVCTAVNVAGSANITVTVEVHAPP--DIKAGPLHYTASEGTPISLSCEARGVPKPTIS 407

Query: 1606 WYK 1608
            W K
Sbjct: 408  WSK 410



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+ V   C   G P P++ W      +  S   +M   +  + T  IR   PED+G +TC
Sbjct: 20  GAEVHISCSASGSPPPKVFWSHGNIFL--SNHHRMSISESGMLT--IRGAAPEDSGNYTC 75

Query: 584 VAKNAAGFASSTTELIVEAPLS 605
           +A N  G AS +  +    P S
Sbjct: 76  LATNEVGTASQSVNVNYAEPPS 97



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G     ECQ  G P P + W +    +  +   +    D +  TL IR V   D+G +TC
Sbjct: 110 GEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQ---DVHRGTLQIRGVQELDSGDYTC 166

Query: 584 VAKNAAGFASSTTELIVEA 602
           VA N AG +S+   L V A
Sbjct: 167 VASNIAGSSSAVVVLQVGA 185



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 5/118 (4%)

Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628
            + P + +S +   Q   +G E  ++    G PPP+V W      L N    +I+   ++ 
Sbjct: 4    EAPSVVVSPQT--QSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSIS---ESG 58

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
            ++ I+      S  YT  A+N  GT+S  V +   + PS      ++  ++ E  ++E
Sbjct: 59   MLTIRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLE 116



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 91/402 (22%), Positives = 145/402 (36%), Gaps = 36/402 (8%)

Query: 943  GKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            G  V + C  S +   K  W H    +S   HR  I E              D G   C+
Sbjct: 20   GAEVHISCSASGSPPPKVFWSHGNIFLSN-HHRMSISES--GMLTIRGAAPEDSGNYTCL 76

Query: 1001 VKDQ--ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEINSETADVVWERDGEIIK 1057
              ++    S  + V    P  I  +Q    V   + A LE + +   + +V  + G++  
Sbjct: 77   ATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDL-- 134

Query: 1058 PKKNKYDF-EKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELPPEIITRL 1113
                   F E+  H   L IR     D G+Y+C+   +   S    V  V   P      
Sbjct: 135  -DLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAAPTFSESP 193

Query: 1114 QNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI--QFSNHIQLTIDGKKQKLKIYDC 1168
             +   + G+  T    + +G    +L+   +DG  I  + S H+  T       L+I   
Sbjct: 194  VDITASVGDNITLPC-IARGFPTPSLIWRRQDGRPIFGKSSGHVG-TSQLPSGALQIQSV 251

Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVE--EPS--INFTLRLPEFILVPANTDAYLTVEI 1220
             +DD G Y CE     G+ K  A +TV   EP   +     +   I  P N    L   I
Sbjct: 252  WVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGI 311

Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280
            P    +  W      +    +  L SD    +L + +   +D   Y C  ++   +  + 
Sbjct: 312  P--LPERIWTHNGKQVRVGGRVFLRSD---GSLHVDRAVPEDAGTYVCTAVNVAGSANIT 366

Query: 1281 VEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321
            V V V  PP I      Y    G+ ++L  + +  P+P   W
Sbjct: 367  VTVEVHAPPDIKAGPLHYTASEGTPISLSCEARGVPKPTISW 408



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 78/362 (21%), Positives = 131/362 (36%), Gaps = 38/362 (10%)

Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103
            V W   G I     ++    + G    L IR  +  D G Y+C+  +E  TA  +V    
Sbjct: 37   VFWSH-GNIFLSNHHRMSISESG---MLTIRGAAPEDSGNYTCLATNEVGTASQSVNVNY 92

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162
              PP I    Q   V  G  A+ E + +     +V+W K   ++  +   +   D  +  
Sbjct: 93   AEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGT 150

Query: 1163 LKIYDCDLDDAGEYSCE----VGNSKCTAIL------TVEEPSINFTLRLPEFILVPANT 1212
            L+I      D+G+Y+C      G+S    +L      T  E  ++ T  + + I +P   
Sbjct: 151  LQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAAPTFSESPVDITASVGDNITLPCIA 210

Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
              +     P  +L       + +   +      S +    L I+    DD+  Y C   +
Sbjct: 211  RGF-----PTPSLIWRRQDGRPIFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKN 265

Query: 1273 ----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL---LVDYQAFPQPNDEWIVNS 1325
                 K+  ++ V  +E PP +V             + L   L+D    P P   W  N 
Sbjct: 266  QFGSIKALARVTVTGLE-PPLLVQGAPSITTMIAQPLNLPCRLLD--GIPLPERIWTHNG 322

Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385
            K ++         D    SL + +    DAG Y     N  G A++ + V +   P    
Sbjct: 323  KQVRVGGRVFLRSD---GSLHVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAPPDIKA 379

Query: 1386 KP 1387
             P
Sbjct: 380  GP 381



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           P+ V+      T     +   C++ +G P P+  W      ++     +++   D   +L
Sbjct: 284 PLLVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGG--RVFLRSDG--SL 339

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
            +    PEDAGT+ C A N AG A+ T  + V AP
Sbjct: 340 HVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAP 374


>UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep:
            Zgc:152904 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 809

 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 130/664 (19%), Positives = 249/664 (37%), Gaps = 50/664 (7%)

Query: 1215 YLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273
            + T     E + + W+  +   I   E+  + ++  +  L I     ++   Y C   DA
Sbjct: 8    FFTCTAIGEPVSINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADA 67

Query: 1274 KSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331
            K  ++    V+E   K+   + +     ++G D  ++ D  + P P   W   ++ I   
Sbjct: 68   KGQSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYKNREITSE 127

Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391
             +++  +   + +L I KV   D G Y+          +++    ++    PP    +L 
Sbjct: 128  PNSRFQV-LPTNNLQILKVGKADEGAYRCEARVEA-RGEIDFRDIVVQVNVPP----VLS 181

Query: 1392 IDSSSINICWDEPENTGNSTI--------IYYVVEYQEIDTTEW--ISVKNITKTQTSIQ 1441
            +   S N   D  E+   + +        + +  +   I+ +E   ++  N  K+  +++
Sbjct: 182  VPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVK 241

Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501
            N+K      +   A N+   + +SE+  + KV  +  I        L+N+T        +
Sbjct: 242  NIKQTDGGPYMCRASNK---AGSSESQLFLKVFVQPHITQ------LRNVTAVEGSAAMI 292

Query: 1502 TCIFGGVPQPKVTWYR--------DGKKLKTAKATYENRXXXXXXXXXXXXXX---XYKC 1550
            +C   G P P+++W R        DG+K K  +     R                  + C
Sbjct: 293  SCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDC 352

Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610
             A +  G  + S  + I+  P    +N+ I    + G+   ++  ++  P   ++W +  
Sbjct: 353  EALSRIGGHQKSMFLDIEYAPKFQ-TNQSIFYSWE-GNPVNISCEVKSNPAATMLWRRER 410

Query: 1611 NKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
              + +    NI   + +  S++ +  +      +Y   A N  G    E  L   D PS 
Sbjct: 411  FTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSS 470

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P   V M  +S+   T+ +  P   GG+ ++ Y I   +  + +  + A          +
Sbjct: 471  PYS-VRMTAVSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEWRSARTHGVQTAVVL 529

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
              L  N  Y  RV A N  G  E   +E       +  PS                Y   
Sbjct: 530  TSLEPNTTYEVRVSAVNGKGQGEFSHTESFQ-TLPIREPSPPTVHGQRGV---GKAYRLG 585

Query: 1789 FPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG 1846
               + +GG PI++Y ++ K  + ++W           A +Q L  NT Y   I ARN  G
Sbjct: 586  LVKQDDGGMPIVEYILKYKTDKEEQWMTKLVPGMNDFALLQPLQWNTRYNVEITARNVKG 645

Query: 1847 TSLP 1850
             S P
Sbjct: 646  LSEP 649



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 84/353 (23%), Positives = 143/353 (40%), Gaps = 42/353 (11%)

Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           TF +    Q   +G D  + C +++ P P ++W +K  EI  + N    +     +  + 
Sbjct: 85  TFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYKNREITSEPNSRFQV-----LPTNN 139

Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASL-PIVLKIKTGEKEPPQVIEPLKSM--IVRQGE 750
           L+I  V K  EG Y   A V   GE     IV+++      PP +  P +S        E
Sbjct: 140 LQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNV----PPVLSVPQQSFNATADYQE 195

Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTL 805
           SV  +    G+P P +TW      ++      L T + G + ++T+ K  K  D G Y  
Sbjct: 196 SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKS-TLTV-KNIKQTDGGPYMC 253

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +A N  G +E+   + V        +P   I + + +T  E     +       P+P I+
Sbjct: 254 RASNKAGSSESQLFLKV------FVQP--HITQLRNVTAVEGSAAMISCTAEGEPLPEIS 305

Query: 866 WYR--------NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917
           W R        + E         +   G+++ L I+ V    D G + C A +  G   H
Sbjct: 306 WRRASDGHSFTDGEKSKDGRVEVRGRHGKSM-LTISGVQLS-DWGRFDCEALSRIG--GH 361

Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTK-WYHNKKEIS 968
              + +D+E     +  Q  + + EG  V + C+  S+  +T  W   +  IS
Sbjct: 362 QKSMFLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFTIS 414



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-TVKGKSWTKIVTVGGSVHE 1924
            PS P +  ++  + R  T+ + +P+S+GG PI+ YII ++ T   + W    T G     
Sbjct: 468  PSSPYSVRMTAVSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEWRSARTHGVQT-A 526

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984
              + +++       R+SA N  G    + ++S +       PSPPT   + R VG    +
Sbjct: 527  VVLTSLEPNTTYEVRVSAVNGKGQGEFSHTESFQ-TLPIREPSPPTVHGQ-RGVGKAYRL 584

Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044
                  + DGG P++ Y +  +   +  WM      +N     ++ L  N  Y + I AR
Sbjct: 585  GL--VKQDDGGMPIVEYILKYKTDKEEQWMTKLVPGMNDFAL-LQPLQWNTRYNVEITAR 641

Query: 2045 NEIGLSEP 2052
            N  GLSEP
Sbjct: 642  NVKGLSEP 649



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 58/282 (20%), Positives = 117/282 (41%), Gaps = 15/282 (5%)

Query: 1137 VRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK-----CTAILT 1190
            + WF    E   SN  + +  +G + +L IY+  +++AG Y C+  ++K      T +L 
Sbjct: 20   INWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADAKGQSQEATVVLE 79

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            + +      ++ P+      + +    V I      V+W+ K   I  +E  +    +  
Sbjct: 80   IYQKLTFREVKTPQEFRQGDDAEVVCDV-ISSPVPAVSWFYKNREIT-SEPNSRFQVLPT 137

Query: 1251 RTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEF--PPKIVDYEREYRIKRG--SDV 1305
              L I K  + D+  Y C   ++A+     +  VV+   PP +   ++ +         V
Sbjct: 138  NNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQSFNATADYQESV 197

Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364
            T        P P   W      I+  + +   +++   ++LT+K ++ TD G Y  R  N
Sbjct: 198  TFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRASN 257

Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI-CWDEPE 1405
              G ++ ++ + +  +P      N+  ++ S+  I C  E E
Sbjct: 258  KAGSSESQLFLKVFVQPHITQLRNVTAVEGSAAMISCTAEGE 299



 Score = 54.4 bits (125), Expect = 3e-05
 Identities = 76/340 (22%), Positives = 141/340 (41%), Gaps = 28/340 (8%)

Query: 863  SITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
            SI W+    E I  +E +  + +G    L I N   E ++G Y+C A+++ G+S     V
Sbjct: 19   SINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIE-NAGIYRCQAADAKGQSQEATVV 77

Query: 922  TIDVEKVTF--VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
                +K+TF  VK  Q+  + ++ + V+ +  +S   +  W++  +EI+  +     Q  
Sbjct: 78   LEIYQKLTFREVKTPQEFRQGDDAE-VVCDVISSPVPAVSWFYKNREITS-EPNSRFQVL 135

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIR-KLQDFEVK---EK 1031
                         D G  +C  + +    +    +VV+  +P  +    Q F      ++
Sbjct: 136  PTNNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQSFNATADYQE 195

Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091
             V    V   S    V W   G  I+  +        G    L ++N    D G Y C  
Sbjct: 196  SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRA 255

Query: 1092 RDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFK--DG- 1143
             +++ ++E  +   V + P  IT+L+N    +G+ A       +G+ L  + W +  DG 
Sbjct: 256  SNKAGSSESQLFLKVFVQPH-ITQLRNVTAVEGSAAMISC-TAEGEPLPEISWRRASDGH 313

Query: 1144 --SEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCE 1179
              ++ + S   ++ + G+  K  L I    L D G + CE
Sbjct: 314  SFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDCE 353



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 2/86 (2%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           +V F C   G P PQ+TW+ +   I+ S+ + +   +   +TL ++ +   D G + C A
Sbjct: 196 SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRA 255

Query: 586 KNAAGFASSTTELIVEAPLSDHGSEM 611
            N AG  SS ++L ++  +  H +++
Sbjct: 256 SNKAG--SSESQLFLKVFVQPHITQL 279



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 31/149 (20%), Positives = 54/149 (36%), Gaps = 2/149 (1%)

Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549
           E + ++   +K    +   AP F       ++ +G+ V   C+V+  P   + W R+   
Sbjct: 353 EALSRIGGHQKSMFLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFT 412

Query: 550 IKPSQDFQM-YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI-VEAPLSDH 607
           I       +  +  D  + L +  V   D G + C A+N  G       L   + P S +
Sbjct: 413 ISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSSPY 472

Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTF 636
              MT              D   G+P +F
Sbjct: 473 SVRMTAVSQRMATVSFMKPDSHGGVPISF 501



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 13/174 (7%)

Query: 647 EGSDILLECRLVAIPEPDIAW--LFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKF 703
           EGS  ++ C     P P+I+W     G      E      +E       S+L I+ V+  
Sbjct: 286 EGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLS 345

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESVILSAQVVGNP 762
             G +   A++R G     + L I+   K      +  +S+    +G  V +S +V  NP
Sbjct: 346 DWGRFDCEALSRIGGHQKSMFLDIEYAPK-----FQTNQSIFYSWEGNPVNISCEVKSNP 400

Query: 763 RPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEG 812
             T+ W +    + +  T +      D  S+  + P   +D G Y   A N+ G
Sbjct: 401 AATMLWRRERFTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIG 454


>UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45;
           Euteleostomi|Rep: Roundabout homolog 2 precursor - Homo
           sapiens (Human)
          Length = 1378

 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 82/312 (26%), Positives = 130/312 (41%), Gaps = 25/312 (8%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           PTF ++P  Q V E   +   C++   P+P + W  K +  +P       I+ D      
Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWK-KDDADLPRGRYD--IKDDY----- 276

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            L+I       EGTY  +A NR G+      L ++     PPQ +   +  IV QG +V 
Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVT 332

Query: 754 LSAQVVGNPRPTITWCKN--------NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805
              +  GNP+P + W K         N+P +     S   T  +TI   ++  D G Y  
Sbjct: 333 FPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQR-SDAGYYIC 391

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +A    G     A + V +   +   PP+ +      T+   GT  L  + T +P+P I+
Sbjct: 392 QALTVAGSILAKAQLEVTDVLTDRP-PPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 450

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W +      P          E   L I N+    D+G Y CVA++S+G++S  A + +  
Sbjct: 451 WLKEG-FTFPGRDPRATIQ-EQGTLQIKNLRIS-DTGTYTCVATSSSGETSWSAVLDVTE 507

Query: 926 EKVTFVKHLQKS 937
              T  K+   S
Sbjct: 508 SGATISKNYDLS 519



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 88/418 (21%), Positives = 161/418 (38%), Gaps = 29/418 (6%)

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKS 1342
            +FPP+IV++  +  + +G   TL    +  P P  EW  + + ++  K    S  +   S
Sbjct: 28   DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 87

Query: 1343 ASLTIKKV-----ENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDS 1394
             SL   ++        D G Y     N  G A   +  + V +L         +++    
Sbjct: 88   GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 147

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454
                +    P      TI +   + +  D  E IS++     +  I N + + +  +   
Sbjct: 148  EPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRG---GKLMISNTRKSDAGMYTCV 204

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513
              N V   D S+  E       T  + PT + +P+  +  E  E +E  C   G PQP V
Sbjct: 205  GTNMVGERD-SDPAEL------TVFERPTFLRRPINQVVLE-EEAVEFRCQVQGDPQPTV 256

Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573
             W +D   L   +   ++                Y CIA N  G++E S  + ++  P  
Sbjct: 257  RWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQF 316

Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK---LENDKEY--NITTKEKTS 1628
             +   D  Q    G         +G P P V W K G++     N  +   +  +   T 
Sbjct: 317  VVRPRD--QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG 374

Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686
             + I  ++RS +  Y  +A   AG+   +  L+V D  +    P+I++  + +++ ++
Sbjct: 375  DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 82/334 (24%), Positives = 132/334 (39%), Gaps = 34/334 (10%)

Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE----NISVAIE 685
           E  PP   + P    V +G    L C+    P P I W   GE +  D+    +  + + 
Sbjct: 27  EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLP 86

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-----ASLPIVLKIKTGEKEPPQVIEP 740
           S    +  ++     K   EG+Y  VA N  GE     ASL + L      + P  V   
Sbjct: 87  SGSLFFLRIVHGRRSKP-DEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDV--- 142

Query: 741 LKSMIVRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799
               +V  GE  IL  Q   G+P PTI W K+   +     +       + I   +K  D
Sbjct: 143 ----VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRK-SD 197

Query: 800 EGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            G+YT    N  G  ++  A +TV        E P F+ R     V E+  ++   +V  
Sbjct: 198 AGMYTCVGTNMVGERDSDPAELTV-------FERPTFLRRPINQVVLEEEAVEFRCQVQG 250

Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
           +P P++ W +++     ++     +D ++   +        D G Y C+A N  GK    
Sbjct: 251 DPQPTVRWKKDD-----ADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEAS 305

Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
           A +T+       V+   +     +G+TV   C+T
Sbjct: 306 ATLTVRAPPQFVVR--PRDQIVAQGRTVTFPCET 337



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 114/495 (23%), Positives = 195/495 (39%), Gaps = 46/495 (9%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
            E  PP+++E    +IV +GE   L+ +  G P PTI W K+ + V+    K D  +H + 
Sbjct: 27   EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVET--DKDDPRSHRML 84

Query: 791  ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA--EPPLFINRFQ----EITV 844
            +          V+  +++  EG     A   + E    NA  E  L  + F+    ++ V
Sbjct: 85   LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV 144

Query: 845  KEKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
                   L  +  R +P P+I W ++   I   E   +       +L+I+N   + D+G 
Sbjct: 145  AAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKE---ERISIRGGKLMISNT-RKSDAGM 200

Query: 904  YKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH 962
            Y CV +N  G + S  A +T+  E+ TF++        EE + V   CQ           
Sbjct: 201  YTCVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVLEE-EAVEFRCQVQGDPQPTVRW 258

Query: 963  NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPE 1018
             K +      R  I++              D G   CI +++    E S  L V+   P+
Sbjct: 259  KKDDADLPRGRYDIKD--DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-PQ 315

Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG--EIIKPKKNKYDFEK--RGHIRK 1073
            F+ + +D  V +        E        V W+++G   ++ P + +    +        
Sbjct: 316  FVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD 375

Query: 1074 LYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL-----PPEIITRLQNQKVNKGNKA 1124
            L I N    D G Y C    +       A++ V ++     PP I+    NQ +     A
Sbjct: 376  LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 435

Query: 1125 TFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178
              + + T GD L  + W K+G    F          ++  L+I +  + D G Y+C    
Sbjct: 436  LLKCKAT-GDPLPVISWLKEG--FTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 492

Query: 1179 EVGNSKCTAILTVEE 1193
              G +  +A+L V E
Sbjct: 493  SSGETSWSAVLDVTE 507



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 3/195 (1%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY- 691
           PP F  +P+ Q V +G  +   C     P+P + W  +G + +   N      S   +  
Sbjct: 313 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQG 749
              L ITN+++   G Y   A+   G       L++     ++ PP +++   +  +   
Sbjct: 373 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            + +L  +  G+P P I+W K          ++         +K  ++ D G YT  A +
Sbjct: 433 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 492

Query: 810 SEGIAETSAVITVEE 824
           S G    SAV+ V E
Sbjct: 493 SSGETSWSAVLDVTE 507



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 103/477 (21%), Positives = 181/477 (37%), Gaps = 57/477 (11%)

Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE-M 1373
            P+P   W    K+    K  + SI  +   L I     +DAG+Y     N  G  D +  
Sbjct: 161  PEPTIYW-KKDKVRIDDKEERISI--RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPA 217

Query: 1374 NVTILDKPSPPGKP-NILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431
             +T+ ++P+   +P N + ++  ++   C  + +     T+ +      + D  +    +
Sbjct: 218  ELTVFERPTFLRRPINQVVLEEEAVEFRC--QVQGDPQPTVRW------KKDDADLPRGR 269

Query: 1432 NITKTQTSIQNLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489
               K   +++  KT S+    +   A N V   +AS T          +     V +P  
Sbjct: 270  YDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLT-------VRAPPQFVVRPRD 322

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK---------LKTAKATYENRXXXXXXXX 1540
             I  +    +   C   G PQP V W ++G +            ++ +            
Sbjct: 323  QIVAQ-GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 381

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ----KPVITISNEDIKQKHKVGDEWLVTAVI 1596
                   Y C A    G +     + +      +P   I      Q   V    L+    
Sbjct: 382  QRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKA 441

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656
             G P P + W K G      ++   T +E+   ++IK L+ S +  YT  A++++G +S 
Sbjct: 442  TGDPLPVISWLKEGFTFPG-RDPRATIQEQ-GTLQIKNLRISDTGTYTCVATSSSGETSW 499

Query: 1657 EVTLKVY-------------DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703
               L V              D P  P  P +  ++++ SVT+ W+P    G L  + Y I
Sbjct: 500  SAVLDVTESGATISKNYDLSDLPGPPSKPQVT-DVTKNSVTLSWQPGTP-GTLPASAYII 557

Query: 1704 EKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758
            E      +N W  VA+  +    Y ++ L  N  Y+F V A NP G S+ +  S+P+
Sbjct: 558  EAFSQSVSNSWQTVANHVKTT-LYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPV 613



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 34/222 (15%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQ--MYYDDDNV 565
           P FV + R +    G TV F C+ +G P+P + W ++ +  ++ P+Q  Q          
Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373

Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625
             L I  +   DAG + C A   AG   +  +L V   L+D                   
Sbjct: 374 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP----------------- 416

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
                  PP   + P  Q +      LL+C+    P P I+WL +G    P  +    I+
Sbjct: 417 -------PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTF-PGRDPRATIQ 468

Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727
                    L+I N++    GTYT VA +  GE S   VL +
Sbjct: 469 EQ-----GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 14/110 (12%)

Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553
           +L VFE+PT   + +  + +E+           V+F CQV+G P+P + W +  A +   
Sbjct: 218 ELTVFERPTFLRRPINQVVLEE---------EAVEFRCQVQGDPQPTVRWKKDDADLPRG 268

Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           +     YD  +  TL I++    D GT+ C+A+N  G   ++  L V AP
Sbjct: 269 R-----YDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 313



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 96/418 (22%), Positives = 162/418 (38%), Gaps = 43/418 (10%)

Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKR----GHI 1071
            P  +    D  V + +   L  +     T  + W +DGE ++  K+     +     G +
Sbjct: 31   PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90

Query: 1072 RKLYIRN--TSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124
              L I +   S  DEG Y C+ R+      S  A + V  L  +      +  V  G  A
Sbjct: 91   FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 150

Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              E +  +G  +  + W KD   I      +++I G K  L I +    DAG Y+C   N
Sbjct: 151  ILECQPPRGHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCVGTN 207

Query: 1183 -----SKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236
                     A LTV E P+    LR P   +V          ++  +      +KK    
Sbjct: 208  MVGERDSDPAELTVFERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDAD 264

Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER 1295
                ++ +  D    TL I+K    D+  Y C+  +     +    + V  PP+ V   R
Sbjct: 265  LPRGRYDIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 321

Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSID---SKSASLTIKKV 1350
            +  + +G  VT   + +  PQP   W    +  ++   +  +P+     S +  LTI  +
Sbjct: 322  DQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 381

Query: 1351 ENTDAGIYKLRLENNCG----HADVEMNVTILDKPSP---PGKPN-ILEIDSSSINIC 1400
            + +DAG Y  +     G     A +E+   + D+P P    G  N  L +D +++  C
Sbjct: 382  QRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKC 439



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 15/118 (12%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923
            PPS+P+   V++ T  SVTL W +P + G  P + YIIE F      SW    TV   V 
Sbjct: 524  PPSKPQ---VTDVTKNSVTLSW-QPGTPGTLPASAYIIEAFSQSVSNSWQ---TVANHVK 576

Query: 1924 E--HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978
               + +  ++     +F + A N  G+S P+  S  VR +      SPP   ++ R V
Sbjct: 577  TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD----ISPPAQGVDHRQV 630


>UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precursor;
           n=22; Euteleostomi|Rep: Neuronal cell adhesion molecule
           precursor - Homo sapiens (Human)
          Length = 1304

 Score = 93.9 bits (223), Expect = 4e-17
 Identities = 114/478 (23%), Positives = 194/478 (40%), Gaps = 48/478 (10%)

Query: 507 SMAPIFV-EKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKP-SQDFQMYYDDD 563
           S +P++  EKL P     G ++   C+   G P P I W   +    P S+      + D
Sbjct: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD 201

Query: 564 NVATLVIREVFPEDAGT-FTCVAK-NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621
               L    V PED    + C A+ N          + V+    D  ++ T+        
Sbjct: 202 ----LYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND-TIAANLSDTE 256

Query: 622 XXXXADILEGIPPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678
                   E  PPTF + +  A   +E  G+ + LEC    +P P I W  K + ++P +
Sbjct: 257 FYGAKSSRER-PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA-KEDGMLP-K 313

Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738
           N +V    +       L+I +V +   G Y  +A N  G     I +++K      P  I
Sbjct: 314 NRTVYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA----PYWI 364

Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKP 794
              +++++  GE   L  +  GNP+P I+W  N  P++  P     K DGDT    I   
Sbjct: 365 TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT---IIFSN 421

Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLV 853
            + +   VY   A N  G    +A + V       AEPP  +     +  V       L 
Sbjct: 422 VQERSSAVYQCNASNEYGYLLANAFVNV------LAEPPRILTPANTLYQVIANRPALLD 475

Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                +P+P+I W++  +  +  E I    +   +E+ +   DS   +G Y CVA N  G
Sbjct: 476 CAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDS---TGTYTCVARNKLG 532

Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH----TVSTKWYHNKKEI 967
            + +   V ++++  T++    +    + G  V  EC+  H    +++  W  + +E+
Sbjct: 533 MAKN--EVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 588



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 117/529 (22%), Positives = 207/529 (39%), Gaps = 53/529 (10%)

Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXX 1545
            +N+   P ED  L C   G P+P+++W  +G  ++ A      +                
Sbjct: 368  QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSS 427

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y+C A N++G +  +  V +  +P   ++  +   +       L+     G P P + 
Sbjct: 428  AVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIE 487

Query: 1606 WYK--NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
            W+K   G+ L  D    I    +   + I   ++  +  YT  A N  G +  EV L++ 
Sbjct: 488  WFKGAKGSALHED----IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543

Query: 1664 DKP---SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVAD 1718
            D      +PE  V+ R      V+ E K    D  L LT   ++ +   P + R+     
Sbjct: 544  DPTWIVKQPEYAVVQR---GSMVSFECKVK-HDHTLSLTVLWLKDNRELPSDERF----T 595

Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT-----ALDVPSXXXXX 1773
            VD+D     +  ++++    +  +A   +    A     +V  T       DVP+     
Sbjct: 596  VDKD--HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDL 653

Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARIQ-KL 1829
                 +D +SV ++W P + N  SPI  + +E +    K   W             Q KL
Sbjct: 654  ELTDQLD-KSVQLSWTPGDDN-NSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKL 711

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889
            S    Y FR+ A N IG SLP  + ++  + K   P   P       S   ++ + W +P
Sbjct: 712  SPYVNYSFRVMAVNSIGKSLPSEASEQY-LTKASEPDKNPTAVEGLGSEPDNLVITW-KP 769

Query: 1890 ----ESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944
                ESNG  P   Y + ++   G   WT +V    +V ++ +         + ++ A N
Sbjct: 770  LNGFESNG--PGLQYKVSWRQKDGDDEWTSVVV--ANVSKYIVSGTPTFVPYLIKVQALN 825

Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993
             +G +     +   +  H+    P  AP  +R+   N+V ++     WD
Sbjct: 826  DMGFA----PEPAVVMGHSGEDLPMVAPGNVRV---NVVNSTLAEVHWD 867



 Score = 84.6 bits (200), Expect = 3e-14
 Identities = 135/647 (20%), Positives = 259/647 (40%), Gaps = 74/647 (11%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PPT +++ PK   +D   +I+++C     P P  +W   G     D++  V ++      
Sbjct: 45   PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               +      +  EG Y   A N  G A S  IV++     + P    E L+ + ++ G+
Sbjct: 105  IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKEKLEPITLQSGQ 161

Query: 751  SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803
            S++L  +  +G P P I W  N+   + LP         +GD +   +L P+  +++ + 
Sbjct: 162  SLVLPCRPPIGLPPPIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 218

Query: 804  TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843
              +  +++ I +    +  VI+V+E           TE          PP F+      +
Sbjct: 219  YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNAS 278

Query: 844  VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             KE  +G +  +  +    P P I W + + ++  + T+ +NF+ + ++++     SE D
Sbjct: 279  NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-KTLQIIHV---SEAD 334

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
            SG+Y+C+A N+ G   H   V +                  E  T+I     +      W
Sbjct: 335  SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394

Query: 961  YHN--KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014
              N    EI+  D    I +G                V +C   ++      +  + V  
Sbjct: 395  LTNGVPIEIAPDDPSRKI-DGDTIIFSNVQERSS--AVYQCNASNEYGYLLANAFVNVLA 451

Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072
              P  +      ++V     A+L+     S    + W +  +     ++ Y   + G   
Sbjct: 452  EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--- 508

Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIE 1129
             L I        G Y+C+ R++   A+  V   ++ P  I+ + +   V +G+  +FE +
Sbjct: 509  TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568

Query: 1130 LTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--- 1183
            +     L   V W KD  E+      + T+D  K  L + D   DD+G Y+C    +   
Sbjct: 569  VKHDHTLSLTVLWLKDNRELPSDE--RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDS 624

Query: 1184 -KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
               +A+L+V  P+       P + +     D  LT ++ D+++ ++W
Sbjct: 625  VSASAVLSVVAPT---PTPAPVYDVPNPPFDLELTDQL-DKSVQLSW 667



 Score = 76.6 bits (180), Expect = 7e-12
 Identities = 165/773 (21%), Positives = 294/773 (38%), Gaps = 84/773 (10%)

Query: 1044 TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102
            T  + W ++  ++   +  Y +FEK      L I + S  D G Y CI ++       T+
Sbjct: 299  TPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNALGAIHHTI 353

Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFS-NHIQLTI 1156
               V+  P  IT  QN  ++ G   T  I    G+   R  W  +G  I+ + +     I
Sbjct: 354  SVRVKAAPYWITAPQNLVLSPGEDGTL-ICRANGNPKPRISWLTNGVPIEIAPDDPSRKI 412

Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216
            DG    +   +     +  Y C   N     +       +N  L  P  IL PANT  Y 
Sbjct: 413  DG--DTIIFSNVQERSSAVYQCNASNEYGYLLANA---FVN-VLAEPPRILTPANT-LYQ 465

Query: 1217 TVEIPDETLDVTWYKKK-SVIE---DTEKFTLISDV----KKRTLIIRKCTEDDQCEYTC 1268
             +      LD  ++      IE     +   L  D+    +  TL I    +D    YTC
Sbjct: 466  VIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 525

Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327
            V  +     K +V +    P  +  + EY + +RGS    +V ++   + +D  +  + +
Sbjct: 526  VARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGS----MVSFECKVK-HDHTLSLTVL 580

Query: 1328 IKKCKHTKPSIDSKSAS---LTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------ 1378
              K     PS +  +     L +  V + D+G Y                ++++      
Sbjct: 581  WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTP 640

Query: 1379 ----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN 1432
                D P+PP    + +    S+ + W  P +  NS I  +++EY++       W     
Sbjct: 641  APVYDVPNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 699

Query: 1433 ITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN- 1490
            ++ TQT+ Q  L    +Y FR  AVN +  S  SE +E Y        ++PT  + L + 
Sbjct: 700  VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 759

Query: 1491 -----ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
                 IT +P    E     G   Q KV+W +     +       N              
Sbjct: 760  PDNLVITWKPLNGFESN---GPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVP 816

Query: 1546 XXYKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               K  A ND G   E + V+G   + +  ++  +++    V +  L     + +P   +
Sbjct: 817  YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV--NVVNSTLAEVHWDPVPLKSI 874

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHS--------SKYTIEASNTAGT 1653
              +  G ++   K  + + + +  +   I   +  ++H         S YT+      G 
Sbjct: 875  RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934

Query: 1654 SSVEVTL-KVYDKP-SKPEGPVIMREI--SRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
                 +  +V++ P   P  P  ++ +  + +S+T+EW PP    G+ LT+Y + K++P 
Sbjct: 935  GEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTL-KYQPI 992

Query: 1710 NNRWIKVADVDRDVET----YCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758
            N+       VD  +      + ++ LN +  Y F   AQ   G    +  E +
Sbjct: 993  NSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAV 1045



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 52/191 (27%), Positives = 87/191 (45%), Gaps = 8/191 (4%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923
            P+ P +  +++   +SV L WT P  +  SPIT +IIE++    K   W     V G+  
Sbjct: 647  PNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 705

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
               ++ +       FR+ A N++G SLP+E+    L K +     PTA   +     N+V
Sbjct: 706  TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 764

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            +T      ++   P L Y ++ R       W  V  V  N  K+ +        Y+I++ 
Sbjct: 765  ITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV--VVANVSKYIVSGTPTFVPYLIKVQ 822

Query: 2043 ARNEIGLS-EP 2052
            A N++G + EP
Sbjct: 823  ALNDMGFAPEP 833



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 12/290 (4%)

Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442
            PP  P I  +D+S   +   E  + G +  +Y+     E    ++I       TQT IQ 
Sbjct: 174  PP--PIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQ 230

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDI 1499
             +  S        +N+   ++ S+T E+Y   K ++ + PT   P  N + +       +
Sbjct: 231  KQPISVKVISVDELNDTIAANLSDT-EFYGA-KSSRERPPTFLTPEGNASNKEELRGNVL 288

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558
             L CI  G+P P + W ++   L   +  Y+N                 Y+CIA N  G 
Sbjct: 289  SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 348

Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
            +  +  V ++  P    + +++      G++  +     G P P + W  NG  +E   +
Sbjct: 349  IHHTISVRVKAAPYWITAPQNLVL--SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 406

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
             + + K     I    ++   S+ Y   ASN  G       + V  +P +
Sbjct: 407  -DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPR 455



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 171/816 (20%), Positives = 308/816 (37%), Gaps = 97/816 (11%)

Query: 721  LPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-- 777
            +P+  K+     +PP + +   K  I+   E++++  +  G P P+ +W +N        
Sbjct: 32   VPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDK 91

Query: 778  --LPTKSDGD-THSITILKPKKVKD-EGVYTLKAENSEGIAETSAVIT--VEEP--TEEN 829
              L T   G  T  I I+   K +  EGVY   A N  G A ++ ++      P  T+E 
Sbjct: 92   DPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEK 151

Query: 830  AEP---------------------PLFI---NRFQEITVKEKGTIKLVARVT-RNPVPSI 864
             EP                     P+     N FQ +   E+ +  L   +   N +P  
Sbjct: 152  LEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 211

Query: 865  TWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            T  R + I       TQ    +  I + + +VD   D+     +A+N +    +GA+ + 
Sbjct: 212  T--REDYICYARFNHTQTIQQKQPISVKVISVDELNDT-----IAANLSDTEFYGAKSSR 264

Query: 924  DVEKVTFVKHLQKSYETEE--GKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981
            +    TF+     +   EE  G  + LEC  +  + T   +  KE   +     + +   
Sbjct: 265  E-RPPTFLTPEGNASNKEELRGNVLSLEC-IAEGLPTPIIYWAKEDGMLPKNRTVYKNFE 322

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETS---TMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038
                       D G  +CI K+   +   T+ V  +  P +I   Q+  +   +   L  
Sbjct: 323  KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC 382

Query: 1039 EINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095
              N      + W  +G  I+   +  D  ++     +   N        Y C   +E   
Sbjct: 383  RANGNPKPRISWLTNGVPIEIAPD--DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGY 440

Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151
                A V V+  PP I+T          N+         G  L  + WFK         H
Sbjct: 441  LLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSAL--H 498

Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207
              + +  +   L+I     D  G Y+C    ++G +K    L +++P+  + ++ PE+ +
Sbjct: 499  EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT--WIVKQPEYAV 556

Query: 1208 VPANTDAYLTVEIP-DETLDVT--WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264
            V   +      ++  D TL +T  W K    +   E+FT    V K  L++   ++DD  
Sbjct: 557  VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSG 612

Query: 1265 EYTCV---LLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPN 1318
             YTCV    LD+ S + +   V   P     Y+     + ++    +   V     P  +
Sbjct: 613  TYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672

Query: 1319 DEWIVNSKIIK-KCKHTKPSI----DSKSASLTIKKVENTDAGIYKLRL--ENNCGHA-D 1370
            +   +   II+ +    KP +       S + T  +++ +    Y  R+   N+ G +  
Sbjct: 673  NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 732

Query: 1371 VEMNVTILDKPSPPGK-PNILE---IDSSSINICWDEPEN--TGNSTIIYYVVEYQEID- 1423
             E +   L K S P K P  +E    +  ++ I W +P N    N   + Y V +++ D 
Sbjct: 733  SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW-KPLNGFESNGPGLQYKVSWRQKDG 791

Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
              EW SV     ++  +    T   Y  +  A+N++
Sbjct: 792  DDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDM 827



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%)

Query: 524 GSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           GS V FEC+V+      +T  W +    +   + F +  D D+   LV+ +V  +D+GT+
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDH---LVVADVSDDDSGTY 614

Query: 582 TCVAKNAAGFASSTTELIVEAP 603
           TCVA       S++  L V AP
Sbjct: 615 TCVANTTLDSVSASAVLSVVAP 636



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 7/109 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE----WISVK-NITK 1435
            PS P    I+     S+ + WD P +  N  +  Y ++YQ I++T      + +K    K
Sbjct: 952  PSAPSSLKIVNPTLDSLTLEWDPPSHP-NGILTEYTLKYQPINSTHELGPLVDLKIPANK 1010

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
            T+ +++NL  ++ Y+F  YA      S +  T E    + E  I  P V
Sbjct: 1011 TRWTLKNLNFSTRYKFYFYAQTSAG-SGSQITEEAVTTVDEAGILPPDV 1058


>UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome
            shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 16
            SCAF15002, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 875

 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 139/652 (21%), Positives = 249/652 (38%), Gaps = 62/652 (9%)

Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398
            D  S+ LT+ K    DAG+YK    N    A+  + V I  K +    P+  E     I 
Sbjct: 65   DESSSILTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIA 124

Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
                + E++   T+++   + ++I   + +  K ++     I+ +K      +      E
Sbjct: 125  DIICDIESSPPPTVLWKY-KGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTC----E 179

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
              +    E    ++VIK      PT+   +   N T +  + ++LTC   G P+P VTW 
Sbjct: 180  GRLMSRGEID--FRVIKVIVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWT 237

Query: 1517 RDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-------SCVVGI 1567
            R+G  L+  +  +  E+                Y CIA N  GE E          V+  
Sbjct: 238  RNGVVLEAGEKYSFNEDGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVF 297

Query: 1568 QQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG-----------NKLE 1614
              KP IT  I+   ++ + +V     +T    G P P + W   G           N++ 
Sbjct: 298  AVKPKITYIINTTALETEEQV----TLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIY 353

Query: 1615 NDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
               + N+ T+   + S + +K +K + + +Y   A +  G       L+V   P K  G 
Sbjct: 354  QSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAP-KIHGD 412

Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKL 1731
            V +      +V I  +       + +         P+ N    V        +Y  I   
Sbjct: 413  VAVYTWEENAVNISCEVQAHPSDVSIVWLRDGLQLPNANA-TNVKIFRTPSSSYLQINPG 471

Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791
            +EN    +   A N +G     ES+  ++  A +VPS            + +  I +   
Sbjct: 472  SENDFGSYNCTASNELG----TESKEFLLIQA-EVPSAPFIIEVRAF--STTAQIQFEEP 524

Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIG 1846
            E  GG P++ YKV+ + +G+              I +++I      T+YQ ++ A N  G
Sbjct: 525  ESTGGVPVLKYKVQWRIKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAINGKG 584

Query: 1847 TSLPYTSDDKIT---------IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
                  +D   T           +    P+ P+     E    S+ + W + + +GGSPI
Sbjct: 585  EGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKGNSMKVSWLK-QDDGGSPI 643

Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949
             +Y+I +K ++   W   + +  +     +  ++   E    + AEN  G S
Sbjct: 644  LHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKS 695



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 75/292 (25%), Positives = 127/292 (43%), Gaps = 10/292 (3%)

Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           TF   P  Q   EG    + C + + P P + W +KG +I  D+++     S+ H     
Sbjct: 108 TFRNAPSPQEFTEGDIADIICDIESSPPPTVLWKYKGRKIQMDKDVRFKELSNNH----- 162

Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
           L+I  +KK  EG YT    +   GE    ++ K+        +V +   +     G+ V 
Sbjct: 163 LQIRGIKKTDEGPYTCEGRLMSRGEIDFRVI-KVIVNVLPTIRVWQTEVNATADVGQPVK 221

Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSEG 812
           L+  V G P P +TW +N   ++A    S + D   +T+L+  K+ DEG YT  A+N  G
Sbjct: 222 LTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEVAKL-DEGEYTCIAKNKAG 280

Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872
            +E    + V +     A  P          ++ +  + L    + +P P+I+W     +
Sbjct: 281 ESEQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCEASGDPTPTISWSYGGNV 340

Query: 873 ISPSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            S  E    N   ++++  V+T  D+ + S + K V    AG+    AR  I
Sbjct: 341 FSEGEQAHLNRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAI 392



 Score = 72.9 bits (171), Expect = 9e-11
 Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 36/292 (12%)

Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705
           D G  + L C +   PEP + W   G  +   E  S   +       S + +  V K  E
Sbjct: 215 DVGQPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDG------SEMTLLEVAKLDE 268

Query: 706 GTYTVVAVNREGEASLPIVLKIKTGE---KEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762
           G YT +A N+ GE+   + L++          P++   + +  +   E V L+ +  G+P
Sbjct: 269 GEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCEASGDP 328

Query: 763 RPTITWCKN------------NKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLK 806
            PTI+W               N+  ++L     T+SD    S+  LK  K  D G Y   
Sbjct: 329 TPTISWSYGGNVFSEGEQAHLNRIYQSLDGNVVTRSDARVSSLN-LKHVKYTDAGQYLCT 387

Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SIT 865
           A ++ G  E SA + V    + + +  ++          E+  + +   V  +P   SI 
Sbjct: 388 ARSAIGEDEQSAYLEVRYAPKIHGDVAVY--------TWEENAVNISCEVQAHPSDVSIV 439

Query: 866 WYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
           W R+  ++ + + T  + F   +   +  N  SE D G Y C ASN  G  S
Sbjct: 440 WLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNELGTES 491



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 25/236 (10%)

Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS-ESTSRSVTLKWTE 1888
            S N    +   A NE+GT     S + + I   +  PS P  F++   + S +  +++ E
Sbjct: 472  SENDFGSYNCTASNELGTE----SKEFLLIQAEV--PSAP--FIIEVRAFSTTAQIQFEE 523

Query: 1889 PESNGGSPITNYIIEFKTVKGKS-WTKIV--TVGGSVHEHCIENIKEKDEIIFRISAENT 1945
            PES GG P+  Y ++++ +KG+S WT+ V     G+++E  I  +K +     ++SA N 
Sbjct: 524  PESTGGVPVLKYKVQWR-IKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAING 582

Query: 1946 VGVSLPTESQSVRLE----------KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995
             G    + +   + E          + A  P+PP    E+   G N +  SW   + DGG
Sbjct: 583  KGEGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKG-NSMKVSWLKQD-DGG 640

Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051
            +P+L Y I  + +  + W    ++  N+    +R L  +  Y + + A NE G SE
Sbjct: 641  SPILHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKSE 696



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 3/77 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  V+  C V+GYP P +TW R   +++  + +  + +D +  TL+  EV   D G +TC
Sbjct: 217 GQPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYS-FNEDGSEMTLL--EVAKLDEGEYTC 273

Query: 584 VAKNAAGFASSTTELIV 600
           +AKN AG +     L V
Sbjct: 274 IAKNKAGESEQELSLRV 290



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 127/656 (19%), Positives = 255/656 (38%), Gaps = 79/656 (12%)

Query: 874  SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
            SP  T+T+N +  +I L +    +E D+G YKC+A+N   ++    +V I  +K+TF ++
Sbjct: 56   SPDITVTRNDESSSI-LTLYKAGTE-DAGVYKCIATNGDQQAESTVKVKI-FQKITF-RN 111

Query: 934  LQKSYETEEG--KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991
                 E  EG    +I + ++S   +  W +  ++I  MD     +E             
Sbjct: 112  APSPQEFTEGDIADIICDIESSPPPTVLWKYKGRKIQ-MDKDVRFKELSNNHLQIRGIKK 170

Query: 992  XDVGVIKCIVK-----DQETSTMLVVKETIPEFIRKLQDFEVKEKDV---AILEVEINSE 1043
             D G   C  +     + +   + V+   +P  IR  Q       DV     L   ++  
Sbjct: 171  TDEGPYTCEGRLMSRGEIDFRVIKVIVNVLPT-IRVWQTEVNATADVGQPVKLTCAVDGY 229

Query: 1044 TADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--- 1099
               +V W R+G +++  + KY F + G   ++ +   +  DEGEY+CI ++++  +E   
Sbjct: 230  PEPMVTWTRNGVVLEAGE-KYSFNEDG--SEMTLLEVAKLDEGEYTCIAKNKAGESEQEL 286

Query: 1100 -------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRW------FKDGS 1144
                   V V  + P+I   +    +    + T   E   GD    + W      F +G 
Sbjct: 287  SLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCE-ASGDPTPTISWSYGGNVFSEGE 345

Query: 1145 EIQFSNHIQLTIDG--------KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192
            +    N I  ++DG        +   L +      DAG+Y C     +G  + +A L V 
Sbjct: 346  QAHL-NRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVR 404

Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE--KFTLISDVK 1249
              P I+  + +  +     N      V+     + + W +    + +       +     
Sbjct: 405  YAPKIHGDVAVYTWEENAVNISC--EVQAHPSDVSIVWLRDGLQLPNANATNVKIFRTPS 462

Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRGSDVTLL 1308
               L I   +E+D   Y C   +   T   +  +++       +  E R     + +   
Sbjct: 463  SSYLQINPGSENDFGSYNCTASNELGTESKEFLLIQAEVPSAPFIIEVRAFSTTAQIQFE 522

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI-YKLRLENNCG 1367
                    P  ++ V  +I  +   T+   D +  ++    +        Y+++L    G
Sbjct: 523  EPESTGGVPVLKYKVQWRIKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAING 582

Query: 1368 HADVEMNVTILDKPSP-----------PGKPNILEID------SSSINICWDEPENTGNS 1410
              + E +     K  P            G PN  ++D       +S+ + W + ++ G S
Sbjct: 583  KGEGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKGNSMKVSWLK-QDDGGS 641

Query: 1411 TIIYYVVEYQEIDTTEW-ISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             I++Y++ Y+ + ++EW   ++  + ++   ++ L+ ++ Y     A NE   S+A
Sbjct: 642  PILHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKSEA 697



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 103/486 (21%), Positives = 192/486 (39%), Gaps = 51/486 (10%)

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEIITRL--QNQKVNKGNKATFEIEL 1130
            L +      D G Y CI  +    AE TV V++  +I  R     Q+  +G+ A    ++
Sbjct: 71   LTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIADIICDI 130

Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-NSKCTAI 1188
                   V W   G +IQ    ++   +     L+I      D G Y+CE    S+    
Sbjct: 131  ESSPPPTVLWKYKGRKIQMDKDVRFK-ELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEID 189

Query: 1189 LTVEEPSINF--TLRLPEFILVPANTDAYLTVEIP------DETLDVTWYKKKSVIEDTE 1240
              V +  +N   T+R+ +   V A  D    V++        E + VTW +   V+E  E
Sbjct: 190  FRVIKVIVNVLPTIRVWQ-TEVNATADVGQPVKLTCAVDGYPEPM-VTWTRNGVVLEAGE 247

Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE------FPPKIVD 1292
            K++   D  + TL+  +  + D+ EYTC+  +   +S  +L + V +        PKI  
Sbjct: 248  KYSFNEDGSEMTLL--EVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITY 305

Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-------------HTKPSID 1339
                  ++    VTL  +    P P   W     +  + +             +     D
Sbjct: 306  IINTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIYQSLDGNVVTRSD 365

Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399
            ++ +SL +K V+ TDAG Y     +  G  +    + +   P   G   +   + +++NI
Sbjct: 366  ARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAPKIHGDVAVYTWEENAVNI 425

Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY---AV 1456
              +   +  + +I+ ++ +  ++      +VK      +S   +   S   F +Y   A 
Sbjct: 426  SCEVQAHPSDVSIV-WLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTAS 484

Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVT 1514
            NE+     +E+ E+  ++ + ++ S      ++  +T      E     GGVP  + KV 
Sbjct: 485  NEL----GTESKEF--LLIQAEVPSAPFIIEVRAFSTTAQIQFEEPESTGGVPVLKYKVQ 538

Query: 1515 WYRDGK 1520
            W   G+
Sbjct: 539  WRIKGR 544



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 58/273 (21%), Positives = 101/273 (36%), Gaps = 12/273 (4%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI---DGKKQKLKIYDCDLDDA 1173
            +++ G    F  E+      + WF    +    N   +T+   D     L +Y    +DA
Sbjct: 22   EISLGESKFFMCEVAGVAKHIDWFGPSGDRIEQNSPDITVTRNDESSSILTLYKAGTEDA 81

Query: 1174 GEYSCEVGNSKCTAILTVEEPSI-NFTLR-LPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            G Y C   N    A  TV+       T R  P          A +  +I         +K
Sbjct: 82   GVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIADIICDIESSPPPTVLWK 141

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-LLDAKSTTKLKV--EVVEFPP 1288
             K      +K     ++    L IR   + D+  YTC   L ++     +V   +V   P
Sbjct: 142  YKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEIDFRVIKVIVNVLP 201

Query: 1289 KIVDYEREYRIKR--GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
             I  ++ E       G  V L      +P+P   W  N  +++  +  K S +   + +T
Sbjct: 202  TIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRNGVVLEAGE--KYSFNEDGSEMT 259

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            + +V   D G Y    +N  G ++ E+++ + D
Sbjct: 260  LLEVAKLDEGEYTCIAKNKAGESEQELSLRVFD 292



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 4/130 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           G +  F C+V G  +  I WF  +   I + S D  +  +D++ + L + +   EDAG +
Sbjct: 26  GESKFFMCEVAGVAK-HIDWFGPSGDRIEQNSPDITVTRNDESSSILTLYKAGTEDAGVY 84

Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641
            C+A N    A ST ++ +   ++   +  +              DI    PPT   K K
Sbjct: 85  KCIATNGDQQAESTVKVKIFQKITFRNAP-SPQEFTEGDIADIICDIESSPPPTVLWKYK 143

Query: 642 AQYVDEGSDI 651
            + +    D+
Sbjct: 144 GRKIQMDKDV 153


>UniRef50_A7RYG4 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 760

 Score = 93.5 bits (222), Expect = 6e-17
 Identities = 106/452 (23%), Positives = 177/452 (39%), Gaps = 47/452 (10%)

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            Y  V Y   D ++  S + I+K    ++     SS RF  Y  N       S + E  KV
Sbjct: 272  YTCVAYNIRDYSDSASAE-ISKVYV-LEQRSPRSSVRFAIYPANN------SASAEISKV 323

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
                 I      KP+ +   E +E   L C+  G P P+V W RDG+  +  + T   R 
Sbjct: 324  FVRPSI------KPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRR 377

Query: 1534 XXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVG-------IQQKPVITISNEDIKQKHK 1585
                           Y C A N+  + E   +V        I+  P +      +     
Sbjct: 378  SRIYIQDVRLEDEGRYTCEARNNARDQEGHPIVATEEIGLYIKSLPRLNKKGTPLTVYSY 437

Query: 1586 VGDEW--LVTAVIEGIPPPEV-IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642
            +G+     +    +G P P V IW+ N  ++ N  E+ +        I   EL+      
Sbjct: 438  LGNPKPVFIRCRFDGYPFPNVTIWFDN-KQIANGTEFAMFD------IITNELE--DFGD 488

Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702
            Y   + N  G+ +V V L    +PS+P    +   ++   VT+ W PP+DDGG+E+ +Y 
Sbjct: 489  YLCWSWNIHGSKNVTVKLTHAREPSRPVN--VKANVTCSRVTLTWDPPIDDGGMEIMQYV 546

Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761
            IE          K+ + +     Y I  L  +  Y  ++ A+N +G  +   E+  I+ +
Sbjct: 547  IEYDG-------KIFNTEDTYPKYYITNLKRDTMYDIKIWARNKMGKGKNNYETVSIITQ 599

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821
                             ID+ + ++ W   E NGG P + YKV + ++  +         
Sbjct: 600  KYCPPSRPIIWFPYEKVIDDTAFFLKWHEPESNGGDPDVRYKVVVSEDLDEGPFAIKTEF 659

Query: 1822 XXAR---IQKLSINTTYQFRIYARNEIGTSLP 1850
               R   + +L     YQ  +++ N+ G S P
Sbjct: 660  TALREYYVDELKFGQRYQLEVFSYNKAGMSEP 691



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 18/205 (8%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            PS+P N   + + SR VTL W  P  +GG  I  Y+IE+         KI     +  ++
Sbjct: 512  PSRPVNVKANVTCSR-VTLTWDPPIDDGGMEIMQYVIEYD-------GKIFNTEDTYPKY 563

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTA--PLEIRMVGSNI 1982
             I N+K       +I A N +G      E+ S+  +K+   PS P    P E +++    
Sbjct: 564  YITNLKRDTMYDIKIWARNKMGKGKNNYETVSIITQKYCP-PSRPIIWFPYE-KVIDDTA 621

Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK-FNIRDLSENHTYMIRI 2041
                W  PE +GG P + Y + + +        + K +   L+ + + +L     Y + +
Sbjct: 622  FFLKWHEPESNGGDPDVRYKVVVSEDLDEGPFAI-KTEFTALREYYVDELKFGQRYQLEV 680

Query: 2042 YARNEIGLSEPLESDEPFKVIPGEG 2066
            ++ N+ G+SEP  +   +  IP EG
Sbjct: 681  FSYNKAGMSEPAIA---YYFIPNEG 702



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 7/170 (4%)

Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843
            V +TW P   +GG  I+ Y +E   +GK +            I  L  +T Y  +I+ARN
Sbjct: 527  VTLTWDPPIDDGGMEIMQYVIEY--DGKIFNTEDTYPKYY--ITNLKRDTMYDIKIWARN 582

Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYI 1901
            ++G          I I +   PPS+P  +   E      +  LKW EPESNGG P   Y 
Sbjct: 583  KMGKGKNNYETVSI-ITQKYCPPSRPIIWFPYEKVIDDTAFFLKWHEPESNGGDPDVRYK 641

Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951
            +       +    I T   ++ E+ ++ +K        + + N  G+S P
Sbjct: 642  VVVSEDLDEGPFAIKTEFTALREYYVDELKFGQRYQLEVFSYNKAGMSEP 691



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 16/190 (8%)

Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797
           I+P+   +V   E   L     GNP P + W ++ +  +       G    I I +  ++
Sbjct: 329 IKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRRSRIYI-QDVRL 387

Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIKLV--- 853
           +DEG YT +A N+    E   ++  EE        P    +   +TV    G  K V   
Sbjct: 388 EDEGRYTCEARNNARDQEGHPIVATEEIGLYIKSLPRLNKKGTPLTVYSYLGNPKPVFIR 447

Query: 854 ARVTRNPVPSIT-WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912
            R    P P++T W+ N +I + +E     FD      +ITN + E D GDY C + N  
Sbjct: 448 CRFDGYPFPNVTIWFDNKQIANGTEFAM--FD------IITN-ELE-DFGDYLCWSWNIH 497

Query: 913 GKSSHGARVT 922
           G  +   ++T
Sbjct: 498 GSKNVTVKLT 507



 Score = 47.2 bits (107), Expect = 0.005
 Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 8/124 (6%)

Query: 1063 YDFEKRGHIRKLYI-RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121
            Y       I K+Y+    S      ++    + S +AE++ V + P I   + ++ V   
Sbjct: 282  YSDSASAEISKVYVLEQRSPRSSVRFAIYPANNSASAEISKVFVRPSI-KPMYDEVVEID 340

Query: 1122 NKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179
             +A  +  + +G+ L  VRW +DG   ++    Q+T+ G++ ++ I D  L+D G Y+CE
Sbjct: 341  EQAYLDC-VGEGNPLPEVRWIRDG---RYERRQQITLGGRRSRIYIQDVRLEDEGRYTCE 396

Query: 1180 VGNS 1183
              N+
Sbjct: 397  ARNN 400



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 27/270 (10%)

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           +  G +++++C +    E    W ++G   +P ++      S+       L + N+    
Sbjct: 32  ISAGKNLVIKCTISG--EQFQGW-YRGGSKIPTDSSQTKYVSNPTSGAYQLHLNNIVVAD 88

Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764
            G Y  +     G  +  + +   T   E  Q +        R   + ++   V G P+P
Sbjct: 89  GGEY--ICRGNRGSKTFQLYVDFTTTHVELIQYL--------RISNADMIDIDVYGYPKP 138

Query: 765 TITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAETS--AVI 820
           T  W KN +P      + S  D  S+   +  ++ D+G YT   A ++ G++      VI
Sbjct: 139 TFVWTKNGQPWNPNEGRFSTQDGGSVKFSR-VEISDQGNYTCTIAVDTLGLSSVKKIEVI 197

Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
           T E P     E P   NR   +TV    T     +    P P   W   N+I+   +   
Sbjct: 198 TFEPP--RLIERPAPFNRL--LTVGYNTTFH--CKAEGYPKPKYRWL--NQIMREVDLSN 249

Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASN 910
             F   +    ITN+    D G+Y CVA N
Sbjct: 250 PRFTVADEYFHITNIQLS-DVGNYTCVAYN 278



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 54/249 (21%), Positives = 91/249 (36%), Gaps = 19/249 (7%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G    F C+ EGYP+P+  W  Q        + +    D+      I  +   D G +TC
Sbjct: 218 GYNTTFHCKAEGYPKPKYRWLNQIMREVDLSNPRFTVADE---YFHITNIQLSDVGNYTC 274

Query: 584 VAKNAAGFA-SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642
           VA N   ++ S++ E+     L       +V            A+I +       K    
Sbjct: 275 VAYNIRDYSDSASAEISKVYVLEQRSPRSSVRFAIYPANNSASAEISKVFVRPSIKPMYD 334

Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
           + V+      L+C     P P++ W+  G     +    + +        S + I +V+ 
Sbjct: 335 EVVEIDEQAYLDCVGEGNPLPEVRWIRDGRY---ERRQQITLGGRR----SRIYIQDVRL 387

Query: 703 FQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
             EG YT  A N    +   PIV   + G       I+ L  +  +     + S   +GN
Sbjct: 388 EDEGRYTCEARNNARDQEGHPIVATEEIG-----LYIKSLPRLNKKGTPLTVYS--YLGN 440

Query: 762 PRPTITWCK 770
           P+P    C+
Sbjct: 441 PKPVFIRCR 449



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 8/110 (7%)

Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
            E  D G Y     N  G  +V + +T   +PS P       +  S + + WD P + G  
Sbjct: 482  ELEDFGDYLCWSWNIHGSKNVTVKLTHAREPSRPVNVKA-NVTCSRVTLTWDPPIDDGGM 540

Query: 1411 TIIYYVVEYQ-EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459
             I+ YV+EY  +I  TE       T  +  I NLK ++ Y  + +A N++
Sbjct: 541  EIMQYVIEYDGKIFNTE------DTYPKYYITNLKRDTMYDIKIWARNKM 584


>UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM protein;
            n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to Nr-CAM protein - Strongylocentrotus purpuratus
          Length = 1235

 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 143/615 (23%), Positives = 228/615 (37%), Gaps = 61/615 (9%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+  ++P++   D    + L CR   IPEP   W   G     D N   +++      
Sbjct: 22   VPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASLDG----- 76

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK----IKTGEKEPPQVI--EPLKSMI 745
               L I ++    +G Y   A NR G A    ++     +   E   P+ I  +  + + 
Sbjct: 77   -GNLVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLK 135

Query: 746  VRQGESVILSAQVVGNPRPTITWC-KNNKPVK-ALPTKSDGDTHSITILKPKKVKD-EGV 802
            +R G S        GNP P I W     KP       + + D     +       D +G 
Sbjct: 136  LRCGGS---PGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGY 192

Query: 803  YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862
            Y     N  G ++ +  +T+    E  A   +      EI ++ +   KL       P P
Sbjct: 193  YCQAINNVVGSSQRTPKVTLMVSVESGAS-LITKPAANEIAIRTQ-LFKLKCIAYGYPTP 250

Query: 863  SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
             ITW R  E +     ++    G+  ELVI+ V++  D G Y CVASN+ G       VT
Sbjct: 251  VITWKRGEEQLQSGGRVSIEESGQ--ELVISTVENS-DKGTYTCVASNTGGDDEFSTVVT 307

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-----HREI 975
              VE   +            G++V +EC++      +  W  N +  +  +      R  
Sbjct: 308  --VESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWT 365

Query: 976  IQEG--RXXXXXXXXXXXXDVGVIKCIV----KDQETSTML---VVKETIPEFIRKLQDF 1026
            +  G  +            D  V +CI     K++ TS +L    +   IP F    +  
Sbjct: 366  VVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPARIPSFTPVTRKL 425

Query: 1027 EVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
             V E   A     +    T  + W   G ++    +KY  ++      + I N    D G
Sbjct: 426  SVVEDSSAAFTCHVEGRPTPTITWTFKGSVL-TNGDKYTIDELA--GSIVINNALEVDSG 482

Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEIELTKGDALVR 1138
             Y C        +D   T   T+  L   IIT    +  V +   ATF+ E+T    L +
Sbjct: 483  AYECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHELDK 542

Query: 1139 ----WFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGNS-KCTAILTVE 1192
                W KDG  ++ +    L ID         Y C ++   + S +  +S   +A L V+
Sbjct: 543  PETYWMKDGQRLEANQDNSLRIDNAMFSNSGTYTCFVETTLDESTDTVHSVNASAQLVVK 602

Query: 1193 ---EPSINFTLRLPE 1204
                P  N  LR  E
Sbjct: 603  GHPGPPQNLQLRAKE 617



 Score = 77.8 bits (183), Expect = 3e-12
 Identities = 215/1035 (20%), Positives = 370/1035 (35%), Gaps = 113/1035 (10%)

Query: 1096 CTAEVTVV-ELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQ 1153
            C A +T+  ++PP I+ + ++   +     T     T   +    W+KDG+     N+ +
Sbjct: 12   CIATLTLAYDVPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDR 71

Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVP 1209
             ++DG    L I      D G+Y C   N   TA    I+T       F    PE I V 
Sbjct: 72   ASLDGGN--LVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVD 129

Query: 1210 ANTDAYL----TVEIPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQ 1263
                  L    +  +P+       Y   +  + T       I+   +  L+       D 
Sbjct: 130  QGRPLKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDA 189

Query: 1264 CEYTC-----VLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLL--VDYQAFP 1315
              Y C     V+  ++ T K+ + V VE    ++       I   + +  L  + Y  +P
Sbjct: 190  KGYYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAY-GYP 248

Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375
             P   W    + ++     + SI+     L I  VEN+D G Y     N  G  +    V
Sbjct: 249  TPVITWKRGEEQLQS--GGRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVV 306

Query: 1376 TILDKPSPPGKPNI-LEIDSSSINI-CWDEPENTGNSTIIYYV-----VEYQE-IDTTEW 1427
            T+   P  P  P+   +    S++I C    E      + + V      +++  IDT  W
Sbjct: 307  TVESAPYFPAPPSDETKGPGESVDIEC--RSEGVPAPAVDWLVNGQPWADFESNIDTERW 364

Query: 1428 ISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486
              V    +  T SI NL+T  S  F+  A N+       E T     +     + P+   
Sbjct: 365  TVVTGNPQLATISISNLQTTDSNVFQCIATNKYK----EELTSVVLNVVSIPARIPSFTP 420

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXX 1545
              + ++   +     TC   G P P +TW   G  L    K T +               
Sbjct: 421  VTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGSVLTNGDKYTIDELAGSIVINNALEVD 480

Query: 1546 X-XYKCIAFN--DHGEVET--SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG-I 1599
               Y+C A N  D  + E   S  + +  K +IT+   D+  +      +      +  +
Sbjct: 481  SGAYECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHEL 540

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI-------EASNTAG 1652
              PE  W K+G +LE +++ ++         RI     S+S  YT        E+++T  
Sbjct: 541  DKPETYWMKDGQRLEANQDNSL---------RIDNAMFSNSGTYTCFVETTLDESTDTVH 591

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
            + +    L V   P  P+   +  +    ++ + W+P  +D    +  Y I+     + +
Sbjct: 592  SVNASAQLVVKGHPGPPQNLQLRAKEQEFAMDLFWEPG-NDNNAPIQYYIIQY----DTK 646

Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772
            W   AD+    +   +       +Y FRVIA N +G SE        +   +  PS    
Sbjct: 647  W---ADMHWQFQAPFV-------DYQFRVIAVNEIGRSEPSAGVAPTVDPQVAPPSKNPI 696

Query: 1773 XXXXXXIDNESVYITWFPSEK--NGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXAR-- 1825
                     ES+ I W        GG      + Y+  +  E    K         A   
Sbjct: 697  EVSGSGTRPESMVIRWQSIHPFYYGGDDFHYEVAYRPRMSSE-PFVKDTVYPENTDANPT 755

Query: 1826 --IQKLSINT-----TYQFRIYARNEIGTSLPYTSDDKITIGKT--LTPPSQPRNFVVSE 1876
              IQ   +N       Y+F + + N  G       + +I  G +    P + P    V  
Sbjct: 756  GIIQNFIVNARKPYEEYEFSVRSMNSGGPG----PEPEIHYGFSGEAAPGASPSGVTVEA 811

Query: 1877 STSRSVTLKW--TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
             ++  V + W   +PE   G  +  Y + +         K + V        + N++   
Sbjct: 812  ISANEVNVTWEPIDPEDANGK-LGGYNVYYNVKIASGQDKQMCVKSPC---VVGNLQAAT 867

Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG 1994
                 + A    G    ++   V  +   + P  P   L++ +    +V+ +W  P    
Sbjct: 868  TYEITVKAFTNAGEGPASDVVEVVTD---SAPPGPVYKLKVDVYSYRLVL-NWQEPILTN 923

Query: 1995 GAPLLGYNIAIRDVT-KTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            G  L GYN+ I  V  +T+  E    + V+     I + S    Y + + A N IG  E 
Sbjct: 924  G-DLTGYNVIITPVVDETLGDEENFPLAVDDDLTLIYEASPETKYRVEVLALNTIGDGEK 982

Query: 2053 LESDEPFKVIPGEGS 2067
              ++EP   + G  S
Sbjct: 983  -TTEEPTTFLQGRPS 996



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F    R     + S+  F C VEG P P ITW  + +++     + +   D+   ++V
Sbjct: 416 PSFTPVTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGSVLTNGDKYTI---DELAGSIV 472

Query: 570 IREVFPEDAGTFTCVAKNA 588
           I      D+G + C A+N+
Sbjct: 473 INNALEVDSGAYECTAENS 491



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
           + +C   GYP P ITW R    ++      +   +++   LVI  V   D GT+TCVA N
Sbjct: 239 KLKCIAYGYPTPVITWKRGEEQLQSGGRVSI---EESGQELVISTVENSDKGTYTCVASN 295

Query: 588 AAGFASSTTELIVEA 602
             G    +T + VE+
Sbjct: 296 TGGDDEFSTVVTVES 310


>UniRef50_UPI0000DA2C8C Cluster: PREDICTED: similar to myosin binding
            protein C, slow type; n=1; Rattus norvegicus|Rep:
            PREDICTED: similar to myosin binding protein C, slow type
            - Rattus norvegicus
          Length = 1162

 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 50/157 (31%), Positives = 86/157 (54%), Gaps = 3/157 (1%)

Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097
            VE+     +V W ++G+ I+P   KY FE +G+ R ++I N ++ D+ EY     DE C+
Sbjct: 300  VELADPKLEVKWFKNGQEIRPS-TKYIFEHKGNERIMFINNCALTDDSEYYVTAGDEKCS 358

Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI--QFSNHIQLT 1155
             E+ V E P  +  +L++     G +   E+E+++ DA V+WFK+G EI     +  ++ 
Sbjct: 359  TELFVREPPIMVTKQLEDMNAYCGERVELEVEVSEDDANVKWFKNGEEIVPGPKSRYRIK 418

Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192
            ++GKK  L I      D+ EYS      + +A L+V+
Sbjct: 419  VEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKLSVD 455



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 3/168 (1%)

Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            +++KG +  F +EL      V+WFK+G EI+ S        G ++ + I +C L D  EY
Sbjct: 289  QIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCALTDDSEY 348

Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK--KKS 1234
                G+ KC+  L V EP I  T +L E +         L VE+ ++  +V W+K  ++ 
Sbjct: 349  YVTAGDEKCSTELFVREPPIMVTKQL-EDMNAYCGERVELEVEVSEDDANVKWFKNGEEI 407

Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            V     ++ +  + KK TLII   T+ D  EY+ +    +S+ KL V+
Sbjct: 408  VPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKLSVD 455



 Score = 59.7 bits (138), Expect = 9e-07
 Identities = 43/182 (23%), Positives = 78/182 (42%), Gaps = 2/182 (1%)

Query: 923  IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981
            ++ +   F K L  +Y+ ++G  V    + +   +  KW+ N +EI          +G  
Sbjct: 273  VEKKSAAFAKILDPAYQIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNE 332

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041
                       D         D++ ST L V+E      ++L+D      +   LEVE++
Sbjct: 333  RIMFINNCALTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVELEVEVS 392

Query: 1042 SETADVVWERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100
             + A+V W ++GE I P  K++Y  +  G    L I   +  D  EYS +      +A++
Sbjct: 393  EDDANVKWFKNGEEIVPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKL 452

Query: 1101 TV 1102
            +V
Sbjct: 453  SV 454



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 41/172 (23%), Positives = 65/172 (37%), Gaps = 5/172 (2%)

Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
            VE+ S  F   L     +         VE+ D  L+V W+K    I  + K+       +
Sbjct: 273  VEKKSAAFAKILDPAYQIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNE 332

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310
            R + I  C   D  EY     D K +T+L V   E P  +     +     G  V L V+
Sbjct: 333  RIMFINNCALTDDSEYYVTAGDEKCSTELFVR--EPPIMVTKQLEDMNAYCGERVELEVE 390

Query: 1311 YQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKL 1360
                   N +W  N  +I+   K   +  ++ K  +L I+     D+  Y +
Sbjct: 391  VSE-DDANVKWFKNGEEIVPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSV 441


>UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13667,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1278

 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 75/297 (25%), Positives = 130/297 (43%), Gaps = 24/297 (8%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           + PT S+  K   V  G  +LLEC    +P P I W  KG ++ P+  +          +
Sbjct: 326 LSPTGSQSSKM--VLRGQQLLLECIAAGVPTPTIKWYRKGGDL-PERKVK------FENF 376

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
              L +  V +   G Y  +A+N +G     I++++K      P  ++   ++++   E+
Sbjct: 377 NKTLLVVGVSEEDAGEYVCMAINHQGSIRHSILVQVKAA----PYWLDKPTNLVLAPNEN 432

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENS 810
             L  +  GNP+P I W  N +P+++ P     D    TI+ +  ++    VY   A N 
Sbjct: 433 GRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVLGDTIIFRSVQMGSSAVYQCNASNQ 492

Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            G   ++A ++V +       P +   + Q I V E     L      +P+P + W++N 
Sbjct: 493 YGYLLSNAFVSVLD-----MPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNG 547

Query: 871 EIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926
           +    S     ++    N  L I    SE D G Y CVAS+  GK+ +  R+ +  E
Sbjct: 548 Q---GSGVDGGHYSVHNNGTLEIKRARSE-DEGTYTCVASSLLGKAENQVRLEVKEE 600



 Score = 83.4 bits (197), Expect = 6e-14
 Identities = 95/441 (21%), Positives = 167/441 (37%), Gaps = 37/441 (8%)

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530
            + ++ + K     ++KP  N+   PNE+  L C   G P+P + W  +G+ ++++     
Sbjct: 406  HSILVQVKAAPYWLDKPT-NLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPS 464

Query: 1531 NRXXXXXXXXXXX---XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587
                                Y+C A N +G + ++  V +   P   +  ++   K    
Sbjct: 465  RDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIEN 524

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
            +   +     G P P++ W+KNG     D   Y++        + IK  +      YT  
Sbjct: 525  NHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSV---HNNGTLEIKRARSEDEGTYTCV 581

Query: 1647 ASNTAGTSSVEVTLKVYDK------------PSKPEGPVIM--REISRESVTIEWKPPLD 1692
            AS+  G +  +V L+V ++            P +P+ P+ +   + +  SV + W P  +
Sbjct: 582  ASSLLGKAENQVRLEVKEEASLNPSVSSALPPDRPDPPLELDLSDPAVRSVRLTWIPG-N 640

Query: 1693 DGGLELTKYAIEKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750
            D    +T + ++  E   +  RW  ++     + +  +Q L     Y FRVIA N VG S
Sbjct: 641  DNRSPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQ-LAPFVNYQFRVIAINSVGQS 699

Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGSPIIDYKVEIK 1807
            E     P   KT+   P               ++ ITW P    E+NG +       + K
Sbjct: 700  EPSLPSP-QYKTSGAAPDVIPRGLRGWGSMKGNMEITWEPLLDLERNGANLYYSVWWKRK 758

Query: 1808 QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT--LTP 1865
               + W            +        YQ +I A NE G+      +  I IG +   TP
Sbjct: 759  DTSEDWNNVTTVRTKHV-VHNTETYVPYQIKIQAGNEFGSG----PESNIIIGYSGEDTP 813

Query: 1866 PSQPRNFVVSESTSRSVTLKW 1886
               P    VS   +    + W
Sbjct: 814  TDAPTELRVSRVDTNRAHIHW 834



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 48/193 (24%), Positives = 73/193 (37%), Gaps = 6/193 (3%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXX 1539
            SPT  +  K +     + + L CI  GVP P + WYR G  L   K  +EN         
Sbjct: 327  SPTGSQSSKMVLR--GQQLLLECIAAGVPTPTIKWYRKGGDLPERKVKFENFNKTLLVVG 384

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599
                    Y C+A N  G +  S +V ++  P       ++          +  A   G 
Sbjct: 385  VSEEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRA--NGN 442

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P + W  NG  +E+  + N +       I  + ++   S+ Y   ASN  G       
Sbjct: 443  PKPNIQWLINGQPIESSPQ-NPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAF 501

Query: 1660 LKVYDKPSKPEGP 1672
            + V D P +  GP
Sbjct: 502  VSVLDMPPRMLGP 514



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 88/447 (19%), Positives = 184/447 (41%), Gaps = 41/447 (9%)

Query: 1057 KPKKNKYDFEKRGHIRKL---YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII--T 1111
            +P ++  D  + G + K+   Y+ + S  ++ E   +   + C     + +  P ++  T
Sbjct: 273  RPDQDGLDMPREGLVNKMVERYLESNSQAEDPEEGLM---DGCGRSRKLPQTMPTLLSPT 329

Query: 1112 RLQNQK-VNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169
              Q+ K V +G +   E I        ++W++ G ++      ++  +   + L +    
Sbjct: 330  GSQSSKMVLRGQQLLLECIAAGVPTPTIKWYRKGGDLP---ERKVKFENFNKTLLVVGVS 386

Query: 1170 LDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-D 1226
             +DAGEY C   N + +    + V+  +  + L  P  +++  N +  L          +
Sbjct: 387  EEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPN 446

Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284
            + W      IE + +     DV   T+I R         Y C   +      +   V V+
Sbjct: 447  IQWLINGQPIESSPQ-NPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVL 505

Query: 1285 EFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343
            + PP+++  + +  ++   +   L   +   P P+  W  N +          S+ + + 
Sbjct: 506  DMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQG-SGVDGGHYSVHN-NG 563

Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---------PPGKPNI-LEID 1393
            +L IK+  + D G Y     +  G A+ ++ + + ++ S         PP +P+  LE+D
Sbjct: 564  TLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSSALPPDRPDPPLELD 623

Query: 1394 SS-----SINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTS-IQNLKT 1445
             S     S+ + W  P N   S + +++V+++E   +   W ++ +      S I  L  
Sbjct: 624  LSDPAVRSVRLTWI-PGNDNRSPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQLAP 682

Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYK 1472
              +Y+FR  A+N V  S+ S  +  YK
Sbjct: 683  FVNYQFRVIAINSVGQSEPSLPSPQYK 709



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 120/580 (20%), Positives = 205/580 (35%), Gaps = 41/580 (7%)

Query: 530  ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF---PED-AGTFTCVA 585
            EC+ +G P P  +W R        +D ++    D+  TL I        ED  G + C A
Sbjct: 24   ECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDS-GTLEINFRSGGKQEDYEGEYQCFA 82

Query: 586  KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP-KAQY 644
             N  G A S  ++++     D                   A  LE   P + K+      
Sbjct: 83   SNELGVALSN-KILLRVSSEDTLLNTCRFSHSSVVSDCFCATTLEA--PLWPKEVLDPVL 139

Query: 645  VDEGSDILLECRLV-AIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKIT-NVK 701
            V EGS ++L C     +P P I W+      IV D+ +S+ +  D++    + K   N  
Sbjct: 140  VTEGSSLILPCNPPPGLPPPLIFWMDSTMTPIVQDKRVSMGLNGDLYFSNVMAKDAHNEY 199

Query: 702  KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761
            K          + ++     P +LK+ T  KEP    +   +     GE    +   +  
Sbjct: 200  KCNARCRLTQTIQQKN----PFILKVHT--KEPFN--DTSHNDTDPYGEDEEDARGQISQ 251

Query: 762  PRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAEN-SEGIAET 816
              P I    +  PV+    K   D   + +    L  K V+       +AE+  EG+ + 
Sbjct: 252  ISPLIVKRASVHPVRCCGGKERPDQDGLDMPREGLVNKMVERYLESNSQAEDPEEGLMDG 311

Query: 817  SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876
                     T      P      + +   ++  ++ +A     P P+I WYR    +   
Sbjct: 312  CGRSRKLPQTMPTLLSPTGSQSSKMVLRGQQLLLECIAAGV--PTPTIKWYRKGGDLPER 369

Query: 877  ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936
            +   +NF   N  L++  V SE D+G+Y C+A N  G   H   V +        K    
Sbjct: 370  KVKFENF---NKTLLVVGV-SEEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNL 425

Query: 937  SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996
                 E   ++     +   + +W  N + I         ++                 V
Sbjct: 426  VLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNP-SRDVLGDTIIFRSVQMGSSAV 484

Query: 997  IKCIVKDQE----TSTMLVVKETIPEFI-RKLQDFEVKEKDVAILEVE-INSETADVVWE 1050
             +C   +Q     ++  + V +  P  +  K Q  +V E +   L+     S   D+ W 
Sbjct: 485  YQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWF 544

Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            ++G+        Y     G    L I+     DEG Y+C+
Sbjct: 545  KNGQGSGVDGGHYSVHNNG---TLEIKRARSEDEGTYTCV 581



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 50/207 (24%), Positives = 81/207 (39%), Gaps = 16/207 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYC 692
           P +  KP    +    +  L CR    P+P+I WL  G+ I    +N S  +  D  ++ 
Sbjct: 416 PYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVLGDTIIFR 475

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751
           SV         Q G+  V   N   +    +     +    PP+++ P   +I V +   
Sbjct: 476 SV---------QMGSSAVYQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIENNH 526

Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811
             L     G+P P + W KN +             +    +K  + +DEG YT  A +  
Sbjct: 527 TFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNGTLEIKRARSEDEGTYTCVASSLL 586

Query: 812 GIAETSAVITVEE-----PTEENAEPP 833
           G AE    + V+E     P+  +A PP
Sbjct: 587 GKAENQVRLEVKEEASLNPSVSSALPP 613



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 7/95 (7%)

Query: 733 EPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK-----PVKALPTKSDGDT 786
           +PP ++ + +K  IV   +++I+  +  GNP P  +W +N K         + T+ D  T
Sbjct: 1   QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60

Query: 787 HSITILKPKKVKD-EGVYTLKAENSEGIAETSAVI 820
             I      K +D EG Y   A N  G+A ++ ++
Sbjct: 61  LEINFRSGGKQEDYEGEYQCFASNELGVALSNKIL 95



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           +C   G P P + WF+     + S     +Y   N  TL I+    ED GT+TCVA +  
Sbjct: 530 DCPFFGSPLPDLRWFKNG---QGSGVDGGHYSVHNNGTLEIKRARSEDEGTYTCVASSLL 586

Query: 590 GFASSTTELIVEAPLS 605
           G A +   L V+   S
Sbjct: 587 GKAENQVRLEVKEEAS 602



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 21/215 (9%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQ---EGKKWKXXXXX-XXXXARIQKLSINTTYQFR 1838
            SV +TW P   N  SP+  + V+ ++   E  +W+          + I +L+    YQFR
Sbjct: 631  SVRLTWIPGNDNR-SPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQLAPFVNYQFR 689

Query: 1839 IYARNEIGTSLP-YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----ESNG 1893
            + A N +G S P   S    T G    P   PR      S   ++ + W EP    E NG
Sbjct: 690  VIAINSVGQSEPSLPSPQYKTSG--AAPDVIPRGLRGWGSMKGNMEITW-EPLLDLERNG 746

Query: 1894 GSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
             +    Y + +K     + W  + TV     +H + N +       +I A N  G S P 
Sbjct: 747  AN--LYYSVWWKRKDTSEDWNNVTTVR---TKHVVHNTETYVPYQIKIQAGNEFG-SGPE 800

Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987
             +  +      T    PT  L +  V +N     W
Sbjct: 801  SNIIIGYSGEDTPTDAPT-ELRVSRVDTNRAHIHW 834



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           PPT  K+    Y VD   +I++EC     P PD +W   G+     ++  VA + D    
Sbjct: 2   PPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGTL 61

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKT 729
               +    ++  EG Y   A N  G A S  I+L++ +
Sbjct: 62  EINFRSGGKQEDYEGEYQCFASNELGVALSNKILLRVSS 100



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 4/67 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +  EC   G P P I W+R+   + P +  ++ +++ N  TL++  V  EDAG + C
Sbjct: 340 GQQLLLECIAAGVPTPTIKWYRKGGDL-PER--KVKFENFN-KTLLVVGVSEEDAGEYVC 395

Query: 584 VAKNAAG 590
           +A N  G
Sbjct: 396 MAINHQG 402



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 4/87 (4%)

Query: 831 EPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI--ISPSETITQNFDGEN 887
           +PP  + +  ++  V  +  I +      NPVP  +W RN +   +     +    D   
Sbjct: 1   QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60

Query: 888 IELVITNVDSEID-SGDYKCVASNSAG 913
           +E+   +   + D  G+Y+C ASN  G
Sbjct: 61  LEINFRSGGKQEDYEGEYQCFASNELG 87



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 6/114 (5%)

Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
           +L+  P     K +   V E +   L+C     P PD+ W   G+    D     ++ ++
Sbjct: 504 VLDMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGG-HYSVHNN 562

Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741
                  L+I   +   EGTYT VA +  G+A   + L++K      P V   L
Sbjct: 563 -----GTLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSSAL 611


>UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
           SCAF14650, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1450

 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 89/284 (31%), Positives = 120/284 (42%), Gaps = 26/284 (9%)

Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           F + P    V  G   +LEC+     PEP I+W   G  +  D++  + I S        
Sbjct: 9   FRQNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANL-NDKDERITIRSGK------ 61

Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754
           L ITN KK   G Y  V  N  GE    I    +    E P  ++  +S++V   ESV  
Sbjct: 62  LMITNTKKSDAGKYICVGTNMVGERESEIA---ELTVLERPTFVKRPRSVVVLAEESVKF 118

Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814
              V G+P PT+ W K++  +         D H++ I +   V DEG YT   EN  G +
Sbjct: 119 HCVVQGDPVPTVRWRKDDSDLPK-GRFEILDDHTLNIRQVTSV-DEGSYTCVVENMVGKS 176

Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--- 871
           E SA +TV  P      P     R QE  V    T +  A  T NP P+I W +      
Sbjct: 177 EASATLTVHVPPAFAVRP-----RNQEAAVGRIVTFQCEA--TGNPQPAIFWQKEGSESL 229

Query: 872 --IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
                P +  ++    +   L ITNV    DSG Y C A N AG
Sbjct: 230 LFSYQPPQPFSRLSVSQTGSLTITNVQHS-DSGFYSCQALNIAG 272



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 17/212 (8%)

Query: 744 MIVRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802
           ++V  GE  +L  Q   G+P PTI+W ++   +     +    +  + I   KK  D G 
Sbjct: 16  VMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKK-SDAGK 74

Query: 803 YTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861
           Y     N  G  E+  A +TV        E P F+ R + + V  + ++K    V  +PV
Sbjct: 75  YICVGTNMVGERESEIAELTV-------LERPTFVKRPRSVVVLAEESVKFHCVVQGDPV 127

Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921
           P++ W +++  +        +    NI  V     + +D G Y CV  N  GKS   A +
Sbjct: 128 PTVRWRKDDSDLPKGRFEILDDHTLNIRQV-----TSVDEGSYTCVVENMVGKSEASATL 182

Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953
           T+ V     V+   ++ E   G+ V  +C+ +
Sbjct: 183 TVHVPPAFAVR--PRNQEAAVGRIVTFQCEAT 212



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 74/295 (25%), Positives = 116/295 (39%), Gaps = 25/295 (8%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-----IIKPSQDFQMYYDDDN 564
           P F  + R +    G  V F+C+  G P+P I W ++ +       +P Q F        
Sbjct: 188 PAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRL-SVSQ 246

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------DHGSEMTVXXXX 617
             +L I  V   D+G ++C A N AG  S  T+ ++E   S        + +        
Sbjct: 247 TGSLTITNVQHSDSGFYSCQALNIAG--SVITKALLEVTDSYFLQAWRKYAAAFFPHWPW 304

Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP- 676
                   +   +  PP   + P  Q V   S ++L C  V IP P I W   G  + P 
Sbjct: 305 LWFAESHHSAGADHPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPA 364

Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
           D  +S+   +DM      L+I   K    G+YT VA +  GEAS    L+++ G      
Sbjct: 365 DSRMSI---TDM----GSLEIRYAKLGDTGSYTCVATSPNGEASWTAHLQVE-GRVWSCC 416

Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791
            + P   + +  G         +      +TW K+N+   A PT    +  S T+
Sbjct: 417 SLRPPADLNLIPGAPSKPEVTDITRTSVMLTW-KSNQSSGAAPTSYLIEAFSYTL 470



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 41/198 (20%), Positives = 79/198 (39%), Gaps = 7/198 (3%)

Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531
            ++ + T ++ PT  K  +++     E ++  C+  G P P V W +D   L   +    +
Sbjct: 89   EIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDLPKGRFEILD 148

Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591
                            Y C+  N  G+ E S  + +   P   +   +  Q+  VG    
Sbjct: 149  DHTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFAVRPRN--QEAAVGRIVT 206

Query: 1592 VTAVIEGIPPPEVIWYKNGNK-----LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646
                  G P P + W K G++      +  + ++  +  +T  + I  ++ S S  Y+ +
Sbjct: 207  FQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLTITNVQHSDSGFYSCQ 266

Query: 1647 ASNTAGTSSVEVTLKVYD 1664
            A N AG+   +  L+V D
Sbjct: 267  ALNIAGSVITKALLEVTD 284



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 57/235 (24%), Positives = 87/235 (37%), Gaps = 21/235 (8%)

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
           +I     SD G  + V            A++     PTF K+P++  V     +   C +
Sbjct: 63  MITNTKKSDAGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVV 122

Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717
              P P + W  K +  +P     +    D H     L I  V    EG+YT V  N  G
Sbjct: 123 QGDPVPTVRWR-KDDSDLPKGRFEIL---DDH----TLNIRQVTSVDEGSYTCVVENMVG 174

Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----- 772
           ++     L +      PP      ++     G  V    +  GNP+P I W K       
Sbjct: 175 KSEASATLTVHV----PPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLL 230

Query: 773 ---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824
              +P +     S   T S+TI   +   D G Y+ +A N  G   T A++ V +
Sbjct: 231 FSYQPPQPFSRLSVSQTGSLTITNVQH-SDSGFYSCQALNIAGSVITKALLEVTD 284



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 65/273 (23%), Positives = 110/273 (40%), Gaps = 23/273 (8%)

Query: 1121 GNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178
            G  A  E +  +G  +  + W +DG+ +   +  ++TI  +  KL I +    DAG+Y C
Sbjct: 21   GEPAVLECQPPRGHPEPTISWRRDGANLNDKDE-RITI--RSGKLMITNTKKSDAGKYIC 77

Query: 1179 EVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232
               N      S+   +  +E P+  F  R    +++   +  +  V   D    V W K 
Sbjct: 78   VGTNMVGERESEIAELTVLERPT--FVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKD 135

Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV 1291
             S +    +F ++ D    TL IR+ T  D+  YTCV+ +    ++    + V  PP   
Sbjct: 136  DSDLPKG-RFEILDD---HTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFA 191

Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-----SASLT 1346
               R      G  VT   +    PQP   W           +  P   S+     + SLT
Sbjct: 192  VRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLT 251

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379
            I  V+++D+G Y  +  N  G    +  + + D
Sbjct: 252  ITNVQHSDSGFYSCQALNIAGSVITKALLEVTD 284



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 60/258 (23%), Positives = 106/258 (41%), Gaps = 27/258 (10%)

Query: 943  GKTVILECQT--SHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999
            G+  +LECQ    H   T  W  +   ++  D R  I+ G+            D G   C
Sbjct: 21   GEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKKS---DAGKYIC 77

Query: 1000 I----VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGE 1054
            +    V ++E+    +     P F+++ +   V  ++       +  +    V W +D  
Sbjct: 78   VGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDS 137

Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIIT 1111
             +   K +++         L IR  +  DEG Y+C++ +   +S  +    V +PP    
Sbjct: 138  DLP--KGRFEILDD---HTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFAV 192

Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSE-IQFSNH-----IQLTIDGKKQKLK 1164
            R +NQ+   G   TF+ E T      + W K+GSE + FS        +L++  +   L 
Sbjct: 193  RPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSV-SQTGSLT 251

Query: 1165 IYDCDLDDAGEYSCEVGN 1182
            I +    D+G YSC+  N
Sbjct: 252  ITNVQHSDSGFYSCQALN 269



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 5/94 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P FV++ R        +V+F C V+G P P + W +  + + P   F++   DD+  TL 
Sbjct: 99  PTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDL-PKGRFEIL--DDH--TLN 153

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           IR+V   D G++TCV +N  G + ++  L V  P
Sbjct: 154 IRQVTSVDEGSYTCVVENMVGKSEASATLTVHVP 187



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 1/90 (1%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440
            P  P KP + +I  +S+ + W   +++G +   Y +  +     + W+++    KT T +
Sbjct: 428  PGAPSKPEVTDITRTSVMLTWKSNQSSGAAPTSYLIEAFSYTLGSRWVTLVEHVKTDTFV 487

Query: 1441 -QNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             +NL+  + Y F   AVN   ISD S  T+
Sbjct: 488  LKNLRPATVYLFMVRAVNSHGISDPSPITD 517



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 73/274 (26%), Positives = 105/274 (38%), Gaps = 44/274 (16%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV--------PDENISVA 683
           +PP F+ +P+ Q    G  +  +C     P+P I W  +G E +        P   +SV+
Sbjct: 186 VPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVS 245

Query: 684 I----------ESDMHMY-CSVLKITN---VKKFQEGT--YTVVAVNREGEASLP----- 722
                       SD   Y C  L I      K   E T  Y + A  +   A  P     
Sbjct: 246 QTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEVTDSYFLQAWRKYAAAFFPHWPWL 305

Query: 723 --IVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL 778
                    G   PP VI+  PL +  V    +V+LS   VG P P I W K+   +   
Sbjct: 306 WFAESHHSAGADHPPPVIKRGPL-NQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPA 364

Query: 779 PTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE--NAEPPLF 835
            ++ S  D  S+ I +  K+ D G YT  A +  G A  +A + VE       +  PP  
Sbjct: 365 DSRMSITDMGSLEI-RYAKLGDTGSYTCVATSPNGEASWTAHLQVEGRVWSCCSLRPPAD 423

Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869
           +N       K +     V  +TR  V  +TW  N
Sbjct: 424 LNLIPGAPSKPE-----VTDITRTSV-MLTWKSN 451



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVHE 1924
            P  P    V++ T  SV L W   +S+G +P T+Y+IE F    G  W  +V        
Sbjct: 428  PGAPSKPEVTDITRTSVMLTWKSNQSSGAAP-TSYLIEAFSYTLGSRWVTLVE-HVKTDT 485

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL-EKHATVP 1966
              ++N++     +F + A N+ G+S P+  + SVR  +  +T+P
Sbjct: 486  FVLKNLRPATVYLFMVRAVNSHGISDPSPITDSVRTQDSPSTIP 529



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 36/164 (21%), Positives = 63/164 (38%), Gaps = 10/164 (6%)

Query: 1507 GVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
            G P+P ++W RDG  L  K  + T  +                Y C+  N  GE E+   
Sbjct: 33   GHPEPTISWRRDGANLNDKDERITIRS-GKLMITNTKKSDAGKYICVGTNMVGERESEIA 91

Query: 1565 -VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             + + ++P        +    +   ++    V++G P P V W K+ + L   + + I  
Sbjct: 92   ELTVLERPTFVKRPRSVVVLAEESVKF--HCVVQGDPVPTVRWRKDDSDLPKGR-FEILD 148

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667
                  + I+++       YT    N  G S    TL V+  P+
Sbjct: 149  DH---TLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPA 189



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891
           PP+        TV    T+ L       P P I W ++  ++SP+++     D  ++E+ 
Sbjct: 320 PPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLEIR 379

Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
              +    D+G Y CVA++  G++S  A + ++
Sbjct: 380 YAKLG---DTGSYTCVATSPNGEASWTAHLQVE 409


>UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ
            precursor; n=14; Amniota|Rep: Phosphotidylinositol
            phosphatase PTPRQ precursor - Homo sapiens (Human)
          Length = 2332

 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 86/355 (24%), Positives = 143/355 (40%), Gaps = 17/355 (4%)

Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735
            + IS  S+ + W PP    G ++T Y I   E D NR  ++  +D    ++ I  L +  
Sbjct: 620  KNISSSSILLYWDPPEYPNG-KITHYTIYAMELDTNRAFQITTIDN---SFLITGLKKYT 675

Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795
            +Y  RV A   VG S   E   I ++T+ D P           +  + + + W P EK  
Sbjct: 676  KYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKPN 735

Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855
            G  II Y+V  K     +           R   L  +T Y   + +    G     +S  
Sbjct: 736  GI-IIAYEVLYKNIDTLYMKNTSTTDIILR--NLRPHTLYNISVRSYTRFGHGNQVSSLL 792

Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915
             +   +T+ P S P N      +S  + L +  P S  G  I  Y I  K   G     I
Sbjct: 793  SVRTSETV-PDSAPENITYKNISSGEIELSFLPPSSPNGI-IKKYTIYLKRSNGNEERTI 850

Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975
             T   S+ ++ I+ +K+  + I  +SA    G  + +   S+  E+ A  P  P     +
Sbjct: 851  NTT--SLTQN-IKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDA--PDSPPQDFSV 905

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAI--RDVTKTMWMEVGKVDVNTLKFNI 2028
            + +    V  SW  P    G  +L Y + +  R   KT+ +    ++++ L +N+
Sbjct: 906  KQLSGVTVKLSWQPPLEPNGI-ILYYTVYVWNRSSLKTINVTETSLELSDLDYNV 959



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 126/636 (19%), Positives = 229/636 (36%), Gaps = 39/636 (6%)

Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447
            N   I SSSI + WD PE   N  I +Y +   E+DT     +  I  +   I  LK  +
Sbjct: 618  NYKNISSSSILLYWDPPEYP-NGKITHYTIYAMELDTNRAFQITTIDNSFL-ITGLKKYT 675

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
             Y+ R  A   V  S  SE  + +    E + +S   +  + ++T +   +I L      
Sbjct: 676  KYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTAD---EIRLKWSPPE 732

Query: 1508 VPQPKVTWYRD-GKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             P   +  Y    K + T   K T                    +      HG   +S +
Sbjct: 733  KPNGIIIAYEVLYKNIDTLYMKNTSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLL 792

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDE----WLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
                 + V   + E+I  K+    E    +L  +   GI     I+ K  N    ++E  
Sbjct: 793  SVRTSETVPDSAPENITYKNISSGEIELSFLPPSSPNGIIKKYTIYLKRSN---GNEERT 849

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT-LKVYDKPSKPEGPVIMREIS 1679
            I T   T  I++ +    +  + +       G  S  ++ L   D P  P     ++++S
Sbjct: 850  INTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLS 909

Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739
              +V + W+PPL+  G+ +  Y +      + + I V +   +     +  L+ N EY  
Sbjct: 910  GVTVKLSWQPPLEPNGI-ILYYTVYVWNRSSLKTINVTETSLE-----LSDLDYNVEYSA 963

Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799
             V A    G  +   S  I  +T    PS          + + S+ + W P  K  G  I
Sbjct: 964  YVTASTRFGDGKT-RSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGI-I 1021

Query: 1800 IDYKVEIKQEGKKWKXXXX---------XXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
              Y V  +     +                     I KL+I + Y F + A   +G    
Sbjct: 1022 QYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNK 1081

Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910
             +   ++   + + P     N      +S ++ + W  P    G       +  +     
Sbjct: 1082 SSDIIEVYTDQDI-PEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRH 1140

Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970
                +VT   S++    +N+++  + I +I+     G S  T +  + ++    VP    
Sbjct: 1141 VRPPLVTYERSIY---FDNLEKYTDYILKITPSTEKGFS-DTYTAQLYIKTEEDVPETSP 1196

Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006
                 + + S  V+ SW  P    GA ++ Y++ ++
Sbjct: 1197 IINTFKNLSSTSVLLSWDPPVKPNGA-IISYDLTLQ 1231



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 81/354 (22%), Positives = 135/354 (38%), Gaps = 34/354 (9%)

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP-PLDDGGLELTKYAIEKHEPDN 1710
            G SS+         P  P   + +   + + V ++W P PL  G +++  + I +HE D 
Sbjct: 1270 GPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDT 1329

Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
              +  ++    + +   ++ ++    Y  RV A   VG      S  +   T   VP   
Sbjct: 1330 IYYKNISGFKTEAKLVGLEPVST---YSIRVSAFTKVGNGNQF-SNVVKFTTQESVPDVV 1385

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS 1830
                       +SV + W P +K  G  I  Y V +++   K               KL 
Sbjct: 1386 QNMQCMAT-SWQSVLVKWDPPKKANGI-ITQYMVTVERNSTKVSPQDHMYTFI----KLL 1439

Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890
             NT+Y F++ A    G     T     T+ +T+  PS P N   S+  S S TL W  P+
Sbjct: 1440 ANTSYVFKVRASTSAGEGDESTCHVS-TLPETV--PSVPTNIAFSDVQSTSATLTWIRPD 1496

Query: 1891 SNGGSPITNYII--EFKTVKGKSWTKIVTV---------GGSVHEHCIENIKEKDEIIFR 1939
            +  G    NY I  + +  K K W     V            + E  +  +K+     F+
Sbjct: 1497 TILGY-FQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQ 1555

Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE-IRMVGSN--IVMTSWGTP 1990
            ++A    G    +   S +     T+P PP  P E + +V ++   +  SW  P
Sbjct: 1556 VAASTNAGYGNASNWISTK-----TLPGPPDGPPENVHVVATSPFSISISWSEP 1604



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 75/406 (18%), Positives = 156/406 (38%), Gaps = 27/406 (6%)

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-----DKP 1666
            +L+ ++ + ITT + + +I    LK+    K  + AS   G SS+     ++     D+P
Sbjct: 650  ELDTNRAFQITTIDNSFLIT--GLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEP 707

Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726
                  V + +++ + + ++W PP    G+ +    + K+   +  ++K    +      
Sbjct: 708  ESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKN--IDTLYMK----NTSTTDI 761

Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786
             ++ L  +  Y   V +    G    + S  + ++T+  VP           I +  + +
Sbjct: 762  ILRNLRPHTLYNISVRSYTRFGHGNQV-SSLLSVRTSETVPDSAPENITYKNISSGEIEL 820

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
            ++ P     G  I  Y + +K+     +           I+ L   T Y   + A    G
Sbjct: 821  SFLPPSSPNGI-IKKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKG 879

Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEFK 1905
              +       +T  +   P S P++F V + +  +V L W  P E NG       II + 
Sbjct: 880  EGVRSAPISILT--EEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNG-------IILYY 930

Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965
            TV   + + + T+  +     + ++    E    ++A    G    T S  +  +     
Sbjct: 931  TVYVWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDG-KTRSNIISFQTPEGA 989

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011
            PS P   +    + S+ ++  W  P    G  +  Y++  R+ + T
Sbjct: 990  PSDPPKDVYYANLSSSSIILFWTPPSKPNGI-IQYYSVYYRNTSGT 1034



 Score = 36.3 bits (80), Expect = 9.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%)

Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEWISVKN 1432
            T + KP PP       + S+ I + W+ P N  N  II Y+V+Y+E+     T +  V++
Sbjct: 93   TNVTKPGPPVFLAGERVGSAGILLSWNTPPNP-NGRIISYIVKYKEVCPWMQTVYTQVRS 151

Query: 1433 ITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466
               + +  + NL   ++Y  +  A N   I   S+
Sbjct: 152  KPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSD 186


>UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle protein;
            n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
            turtle protein - Nasonia vitripennis
          Length = 1402

 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 92/401 (22%), Positives = 159/401 (39%), Gaps = 38/401 (9%)

Query: 633  PPTFSKKPKAQ-YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PP F+  P+   YV+ G  I+L C+    P P+I W      + P   +++  +      
Sbjct: 309  PPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG----- 363

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
             + L+I+ +K    G YT +A N EG+ S    + I  G      +  P ++    +GE+
Sbjct: 364  -TELRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGG----AVITIPPQNETKLEGEN 418

Query: 752  VILSAQVVGNP-RPTITWCKNNKP---VKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
            V+   +    P   T++W +   P   V  L T++         + P    D G Y    
Sbjct: 419  VVFPCEAKALPGNVTVSWYREGAPISEVSELDTRASVRMDGSLAINPVSADDSGTYLCTV 478

Query: 808  ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866
             N  G  +T SA + VE P +    P +     Q +  +  G ++   +    P+  +TW
Sbjct: 479  SNGIGEPQTASAYLNVEYPAKVTFNPTV-----QYLPFRMAGVVQCYIK-ANPPLQYVTW 532

Query: 867  YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDV 925
             ++  ++ P +       G N  L+ T V +E   G Y C   N+ G + S G    +  
Sbjct: 533  TKDKRLLEPYQVKDIVVMG-NGSLLFTRV-NENHHGQYTCTPYNAHGTQGSSGYMEVLVR 590

Query: 926  EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-----WYHNKKEISGMDHREIIQEGR 980
                F    Q  Y+ + G+TV + C    +  T+     W     E       +++    
Sbjct: 591  NPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRAKVV---- 646

Query: 981  XXXXXXXXXXXXDVGVIKCIVKDQET----STMLVVKETIP 1017
                        D GV +C+V ++      ST L+V+ T P
Sbjct: 647  GGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIVEGTQP 687



 Score = 80.6 bits (190), Expect = 4e-13
 Identities = 102/455 (22%), Positives = 186/455 (40%), Gaps = 45/455 (9%)

Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090
            D  IL  +   + T +++W +D   ++P            +R   I      D G+Y+C+
Sbjct: 326  DAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDGTELR---ISTIKTEDIGDYTCL 382

Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141
             R+     S TA V      V+ +PP+  T+L+ + V        E +   G+  V W++
Sbjct: 383  ARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENV----VFPCEAKALPGNVTVSWYR 438

Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEP- 1194
            +G+ I   + +      +    L I     DD+G Y C V N        +A L VE P 
Sbjct: 439  EGAPISEVSELDTRASVRMDGSLAINPVSADDSGTYLCTVSNGIGEPQTASAYLNVEYPA 498

Query: 1195 --SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252
              + N T++   F +       Y+    P +   VTW K K ++E  +   ++  +   +
Sbjct: 499  KVTFNPTVQYLPFRMAGV-VQCYIKANPPLQY--VTWTKDKRLLEPYQVKDIVV-MGNGS 554

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKST--TKLKVEV-VEFPPKI-VDYEREYRIKRGSDVTL- 1307
            L+  +  E+   +YTC   +A  T  +   +EV V  PP   V+ +  Y+ K G  V + 
Sbjct: 555  LLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEVLVRNPPVFTVEPQPMYQRKVGETVEMH 614

Query: 1308 --LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365
                +     +P   W    K  ++    +  +     +LTI+ ++  D G+Y+  + N 
Sbjct: 615  CAAQESSGTQKPTVTW--QRKDGEELARGRAKV--VGGNLTIENLKQQDFGVYECVVSNE 670

Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424
                 V+    I++   P    N+  + D  S+ + W    + G      Y + ++E   
Sbjct: 671  VA-TIVKSTHLIVEGTQPHAPHNVTGVADQFSVTLSWQPGYSGGPDYKQDYTIWHREEGA 729

Query: 1425 TEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457
             EW  I V     T  +I  LK+ +++ F+    N
Sbjct: 730  QEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGKN 764



 Score = 74.1 bits (174), Expect = 4e-11
 Identities = 75/272 (27%), Positives = 112/272 (41%), Gaps = 24/272 (8%)

Query: 832  PPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890
            PP F    +E+     G  I L  +    P P I WY++   + PS T+T   DG   EL
Sbjct: 309  PPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG--TEL 366

Query: 891  VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTVILE 949
             I+ + +E D GDY C+A N  G+ SH ARV I    V  +       ET+ EG+ V+  
Sbjct: 367  RISTIKTE-DIGDYTCLARNGEGQISHTARVIIAGGAVITI---PPQNETKLEGENVVFP 422

Query: 950  CQTS---HTVSTKWYHNK---KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003
            C+       V+  WY       E+S +D R  ++               D G   C V +
Sbjct: 423  CEAKALPGNVTVSWYREGAPISEVSELDTRASVR--MDGSLAINPVSADDSGTYLCTVSN 480

Query: 1004 -----QETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057
                 Q  S  L V+      F   +Q    +   V    ++ N     V W +D  +++
Sbjct: 481  GIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLE 540

Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
            P + K D    G+   L+ R    H  G+Y+C
Sbjct: 541  PYQVK-DIVVMGNGSLLFTRVNENH-HGQYTC 570



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 70/243 (28%), Positives = 105/243 (43%), Gaps = 16/243 (6%)

Query: 695 LKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           L +TN+++  +G Y   VV +NR    +             P   I P + + V  G+++
Sbjct: 269 LNLTNIQESDQGWYECKVVFLNRSPNNNKNGTWFHLDVHAPPRFTITPEEMIYVNLGDAI 328

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812
           IL+ Q  G P P I W K+  PV+   T +  +  +   +   K +D G YT  A N EG
Sbjct: 329 ILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDGTELRISTIKTEDIGDYTCLARNGEG 388

Query: 813 -IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
            I+ T+ VI           PP    + +     E       A+     V +++WYR   
Sbjct: 389 QISHTARVIIAGGAV--ITIPPQNETKLE----GENVVFPCEAKALPGNV-TVSWYREGA 441

Query: 872 IISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---K 927
            IS  SE  T+     +  L I  V ++ DSG Y C  SN  G+    A   ++VE   K
Sbjct: 442 PISEVSELDTRASVRMDGSLAINPVSAD-DSGTYLCTVSNGIGE-PQTASAYLNVEYPAK 499

Query: 928 VTF 930
           VTF
Sbjct: 500 VTF 502



 Score = 60.1 bits (139), Expect = 7e-07
 Identities = 96/404 (23%), Positives = 154/404 (38%), Gaps = 59/404 (14%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G  +   CQ EG P P+I W++    ++PS    +  D      L I  +  ED G +TC
Sbjct: 325 GDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG---TELRISTIKTEDIGDYTC 381

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
           +A+N  G  S T  +I+       G+ +T                   IPP    K    
Sbjct: 382 LARNGEGQISHTARVIIAG-----GAVIT-------------------IPPQNETKL--- 414

Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702
              EG +++  C   A+P    ++W  +G  I   E   +   + + M  S L I  V  
Sbjct: 415 ---EGENVVFPCEAKALPGNVTVSWYREGAPI--SEVSELDTRASVRMDGS-LAINPVSA 468

Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGN 761
              GTY     N  GE   P         + P +V   P    +  +   V+        
Sbjct: 469 DDSGTYLCTVSNGIGE---PQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANP 525

Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSAV- 819
           P   +TW K+ + ++    K      + ++L  +      G YT    N+ G   +S   
Sbjct: 526 PLQYVTWTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQYTCTPYNAHGTQGSSGYM 585

Query: 820 -ITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNEIISPS 876
            + V  P     EP P++  +  E TV+     +  +   +   P++TW R + E ++  
Sbjct: 586 EVLVRNPPVFTVEPQPMYQRKVGE-TVEMHCAAQESSGTQK---PTVTWQRKDGEELARG 641

Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG---KSSH 917
                   G N  L I N+  + D G Y+CV SN      KS+H
Sbjct: 642 RA---KVVGGN--LTIENLKQQ-DFGVYECVVSNEVATIVKSTH 679



 Score = 56.4 bits (130), Expect = 8e-06
 Identities = 100/498 (20%), Positives = 177/498 (35%), Gaps = 43/498 (8%)

Query: 1284 VEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342
            V  PP+  +  E    +  G  + L    +  P P   W  ++  ++       +I +  
Sbjct: 306  VHAPPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTV--TIINDG 363

Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401
              L I  ++  D G Y     N  G       V I         P N  +++  ++    
Sbjct: 364  TELRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENVVFPC 423

Query: 1402 DEPENTGNSTIIYY-----VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456
            +     GN T+ +Y     + E  E+DT   + +        +I  +  + S  +     
Sbjct: 424  EAKALPGNVTVSWYREGAPISEVSELDTRASVRMDG----SLAINPVSADDSGTYLCTVS 479

Query: 1457 NEVDISDASETTEYYKVIKETKIQ-SPTVEK-PLKNITTEPNEDIELTCIFGGVPQPKVT 1514
            N   I +    + Y  V    K+  +PTV+  P +         +    I    P   VT
Sbjct: 480  N--GIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMA------GVVQCYIKANPPLQYVT 531

Query: 1515 WYRDGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--CVVGIQQ 1569
            W +D + L+  +                        Y C  +N HG   +S    V ++ 
Sbjct: 532  WTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEVLVRN 591

Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIE---GIPPPEVIWY-KNGNKLENDKEYNITTKE 1625
             PV T+  + + Q+ KVG+   +    +   G   P V W  K+G +L   +      K 
Sbjct: 592  PPVFTVEPQPMYQR-KVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGR-----AKV 645

Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE-SVT 1684
                + I+ LK+     Y    SN   T      L V  + ++P  P  +  ++ + SVT
Sbjct: 646  VGGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIV--EGTQPHAPHNVTGVADQFSVT 703

Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744
            + W+P    G      Y I   E     W  +        T  I +L     + F+V+ +
Sbjct: 704  LSWQPGYSGGPDYKQDYTIWHREEGAQEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGK 763

Query: 1745 NPVGFSEALESEPIVIKT 1762
            N +G  + + S  I ++T
Sbjct: 764  NALG--DGMSSGIITVRT 779



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 75/354 (21%), Positives = 134/354 (37%), Gaps = 29/354 (8%)

Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISD 1247
            L V  P   FT+   E I V       L  +     T ++ WYK  + +E +   T+I+D
Sbjct: 304  LDVHAPP-RFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIIND 362

Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK-RGSDVT 1306
              +  L I     +D  +YTC+  + +        V+     ++    +   K  G +V 
Sbjct: 363  GTE--LRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENVV 420

Query: 1307 LLVDYQAFP-QPNDEWIVNSKIIKKCKH--TKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
               + +A P      W      I +     T+ S+     SL I  V   D+G Y   + 
Sbjct: 421  FPCEAKALPGNVTVSWYREGAPISEVSELDTRASV-RMDGSLAINPVSADDSGTYLCTVS 479

Query: 1364 NNCGH---ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
            N  G    A   +NV    K +       L    + +  C+ +      +  + YV   +
Sbjct: 480  NGIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKA-----NPPLQYVTWTK 534

Query: 1421 EIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479
            +    E   VK+I      S+   + N ++  + Y     +      ++ Y +V+    +
Sbjct: 535  DKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQ-YTCTPYNAHGTQGSSGYMEVL----V 589

Query: 1480 QSPTV--EKPLKNITTEPNEDIELTCI---FGGVPQPKVTWYR-DGKKLKTAKA 1527
            ++P V   +P      +  E +E+ C      G  +P VTW R DG++L   +A
Sbjct: 590  RNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRA 643



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 2/83 (2%)

Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           +G  V F C+ +  P    ++W+R+ A I    +           +L I  V  +D+GT+
Sbjct: 415 EGENVVFPCEAKALPGNVTVSWYREGAPISEVSELDTRASVRMDGSLAINPVSADDSGTY 474

Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603
            C   N  G   +++  L VE P
Sbjct: 475 LCTVSNGIGEPQTASAYLNVEYP 497


>UniRef50_UPI0000D9D1DB Cluster: PREDICTED: similar to obscurin,
            cytoskeletal calmodulin and titin-interacting RhoGEF;
            n=1; Macaca mulatta|Rep: PREDICTED: similar to obscurin,
            cytoskeletal calmodulin and titin-interacting RhoGEF -
            Macaca mulatta
          Length = 381

 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 3/184 (1%)

Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKR 1068
            M+V+   +   +R L+D  V E   A  ++E++ E     W R G  + P   K      
Sbjct: 1    MVVIARQL-RVLRPLEDVTVSEGGSATFQLELSQEGVTGEWARGGVRLHPGP-KCHIHSE 58

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128
            GH  +L ++   + D G  S       C A + V E+P  I+   Q+ +V +G+ AT E 
Sbjct: 59   GHSHRLVLKGLGLADSGCVSFTADSLRCAARLVVREVPVTIVQGPQDLEVTEGDTATLEC 118

Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188
            EL++  A V W KDG+ +  S  ++L   G ++ L++  C   DAG YSC VG ++   +
Sbjct: 119  ELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCSPSDAGTYSCAVGTTRAGPV 178

Query: 1189 -LTV 1191
             LTV
Sbjct: 179  RLTV 182



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 1/171 (0%)

Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159
            + V+     ++  L++  V++G  ATF++EL++      W + G  +       +  +G 
Sbjct: 1    MVVIARQLRVLRPLEDVTVSEGGSATFQLELSQEGVTGEWARGGVRLHPGPKCHIHSEGH 60

Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219
              +L +    L D+G  S    + +C A L V E  +   ++ P+ + V     A L  E
Sbjct: 61   SHRLVLKGLGLADSGCVSFTADSLRCAARLVVREVPVTI-VQGPQDLEVTEGDTATLECE 119

Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270
            +     DVTW K  + +  + +  L +   +R L +R+C+  D   Y+C +
Sbjct: 120  LSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCSPSDAGTYSCAV 170



 Score = 63.7 bits (148), Expect = 5e-08
 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 2/149 (1%)

Query: 942  EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000
            EG +   + + S   V+ +W      +       I  EG             D G +   
Sbjct: 21   EGGSATFQLELSQEGVTGEWARGGVRLHPGPKCHIHSEGHSHRLVLKGLGLADSGCVSFT 80

Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060
                  +  LVV+E     ++  QD EV E D A LE E++   ADV WE+DG  + P  
Sbjct: 81   ADSLRCAARLVVREVPVTIVQGPQDLEVTEGDTATLECELSQALADVTWEKDGNALTPSP 140

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089
             +   +  G  R L +R  S  D G YSC
Sbjct: 141  -RLRLQALGTRRLLQLRRCSPSDAGTYSC 168



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 1/171 (0%)

Query: 1113 LQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
            LQ ++ +  +  T+   + T     VR    G  ++    +++  +GKK  L + +   +
Sbjct: 153  LQLRRCSPSDAGTYSCAVGTTRAGPVRLTVRGRPLRPGARVRIRQEGKKHILVLSELRAE 212

Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231
            DAGE   + G ++  A+L VE   +      P    V     A L V +      V W +
Sbjct: 213  DAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLMGRRAVLEVTVSRSGSHVCWLR 272

Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282
            + + +   +K+ + S     +L+I     +DQ  Y C      + T+L VE
Sbjct: 273  EGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSAHTRLLVE 323



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%)

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093
            A+LEV ++   + V W R+G  + P  +KY+    G    L I +    D+G Y C    
Sbjct: 255  AVLEVTVSRSGSHVCWLREGAELCPG-DKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQ 313

Query: 1094 ESCTAEVTV 1102
            +S    + V
Sbjct: 314  DSAHTRLLV 322



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600
           + W R+ A + P   ++M        +LVI +V PED GT+ C     AG  S+ T L+V
Sbjct: 268 VCWLREGAELCPGDKYEMR-SHGPTHSLVIHDVRPEDQGTYCC----QAGQDSAHTRLLV 322

Query: 601 EA 602
           EA
Sbjct: 323 EA 324


>UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome shotgun
            sequence; n=2; Tetraodontidae|Rep: Chromosome 9
            SCAF14991, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1049

 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 142/643 (22%), Positives = 250/643 (38%), Gaps = 62/643 (9%)

Query: 866  WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
            W  N  +I+      +   G N  L+I+++D   D G Y+C+A N+AG +    R ++  
Sbjct: 92   WSLNGTLINLGLDRRRRLSGGN--LIISSLDRYQDVGMYQCMAFNTAG-AILSRRASLQF 148

Query: 926  EKVTFVK-HLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKE-ISGMDHREIIQEGR 980
              +   K H + +    EG+ V+L C T   S  ++  W  N+       D+R  + + +
Sbjct: 149  AYLDHFKVHTRSAVSVREGQGVVLLCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQ-Q 207

Query: 981  XXXXXXXXXXXXDVGVIKCIV-------KDQETSTMLVVKET--IPEFIRKLQ-----DF 1026
                        DVG   C+V       K Q + T L+++    + E+  K++     + 
Sbjct: 208  TGNLYIAKVEPSDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNV 267

Query: 1027 EVKEKDVAILEV-EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085
                     LE   + +   ++ W+R   +  P K K  +        L I +    D G
Sbjct: 268  SAARGSTVTLECFALGNPVPEITWKRANGVPFPSKVKMKYSNA----VLEIPSFQQDDTG 323

Query: 1086 EYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK 1141
             Y C+  +       T        P+ I  +++  +    +  +E     K      W K
Sbjct: 324  GYECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLK 383

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI----- 1196
            +G ++   + I +  DG    L +    L DAG Y C V  +K   I  V E  +     
Sbjct: 384  NGQQLLSGDRITVE-DGV---LSVPALALSDAGMYQC-VAENKHGVIYFVAELMVLASPP 438

Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTL 1253
            +FT  L   +L  A     +T+E   +   V    W K    I   ++ TL SD    TL
Sbjct: 439  DFTGNLLRALL-KAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSD---GTL 494

Query: 1254 IIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311
             +   ++ D   YTC   +    S+T  ++ V + P +I     +  I  G  + L    
Sbjct: 495  RLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTD-PTRITQGPADMEIIVGESIVLPCQV 553

Query: 1312 QAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGH 1368
             + P    +  W  N ++I K       +  ++A  L I+ ++   AG Y   ++ +   
Sbjct: 554  ASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVES 613

Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428
                  + +   PSPP    + E+  S+  + W    + G S I+ Y V+ +   T  W 
Sbjct: 614  LSAVAILIVKGPPSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNYFVQTRTPFTVGWQ 672

Query: 1429 SVKNITK-----TQT-SIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             V  + +     T T ++ +L     Y FR  A N V + + S
Sbjct: 673  RVNTVPEIIDGNTLTATVVDLNAWVEYEFRVLARNSVGVGEPS 715



 Score = 86.2 bits (204), Expect = 9e-15
 Identities = 93/336 (27%), Positives = 142/336 (42%), Gaps = 32/336 (9%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           GS + LEC  +  P P+I W  K    VP  +     +  M    +VL+I + ++   G 
Sbjct: 272 GSTVTLECFALGNPVPEITW--KRANGVPFPS-----KVKMKYSNAVLEIPSFQQDDTGG 324

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           Y  VA NR G+      L         PQ I+ +K   +   E +    +  G P+P+  
Sbjct: 325 YECVAENRMGKNMATGRLAFYA----KPQWIQAVKDTALAIEERLHWECRANGKPKPSYA 380

Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827
           W KN + + +    +  D   +  +    + D G+Y   AEN  G+    A + V     
Sbjct: 381 WLKNGQQLLSGDRITVED--GVLSVPALALSDAGMYQCVAENKHGVIYFVAELMV----- 433

Query: 828 ENAEPPLFINRFQEITVKEKG--TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
             A PP F        +K K   T+ L  +    PV SI W + N  I  ++ IT + DG
Sbjct: 434 -LASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSDG 492

Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945
               L + NV S+ D+G Y C A N  G SS   R+   V   T +       E   G++
Sbjct: 493 ---TLRLANV-SKSDAGGYTCFARNRFGMSSTTGRLL--VTDPTRITQGPADMEIIVGES 546

Query: 946 VILECQTSH----TVSTKWYHNKKEIS-GMDHREII 976
           ++L CQ +      VS  W  N + I+ G  H E++
Sbjct: 547 IVLPCQVASDPVLDVSFSWAFNGQLIAKGDGHFELV 582



 Score = 72.5 bits (170), Expect = 1e-10
 Identities = 120/531 (22%), Positives = 214/531 (40%), Gaps = 50/531 (9%)

Query: 695  LKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753
            L I+++ ++Q+ G Y  +A N  G A L     ++    +  +V     ++ VR+G+ V+
Sbjct: 114  LIISSLDRYQDVGMYQCMAFNTAG-AILSRRASLQFAYLDHFKV-HTRSAVSVREGQGVV 171

Query: 754  LSAQVVGNPRPT----ITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKA 807
            L   + G P  +      W  N  P           +     L   KV+  D G YT   
Sbjct: 172  L---LCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQQTGNLYIAKVEPSDVGNYTCVV 228

Query: 808  ENS--EGIAETS--AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
             NS  +G  ++S  A+I   +      EP + +N    ++     T+ L      NPVP 
Sbjct: 229  TNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVSAARGSTVTLECFALGNPVPE 288

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            ITW R N +  PS+ +   +    +E+     D   D+G Y+CVA N  GK+    R+  
Sbjct: 289  ITWKRANGVPFPSK-VKMKYSNAVLEIPSFQQD---DTGGYECVAENRMGKNMATGRLAF 344

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRX 981
               K  +++ ++ +    E + +  EC+ +     S  W  N +++   D R  +++G  
Sbjct: 345  -YAKPQWIQAVKDTALAIE-ERLHWECRANGKPKPSYAWLKNGQQLLSGD-RITVEDG-- 399

Query: 982  XXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037
                       D G+ +C+ +++         L+V  + P+F   L    +K K    + 
Sbjct: 400  -VLSVPALALSDAGMYQCVAENKHGVIYFVAELMVLASPPDFTGNLLRALLKAKAGTTVT 458

Query: 1038 VEINSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            +E   +    A ++W++ G +     ++      G +R   + N S  D G Y+C  R+ 
Sbjct: 459  LECKPQAYPVASILWKK-GNLPIHINDRITLSSDGTLR---LANVSKSDAGGYTCFARNR 514

Query: 1095 ---SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-Q 1147
               S T    +V  P  I     + ++  G       ++      D    W  +G  I +
Sbjct: 515  FGMSSTTGRLLVTDPTRITQGPADMEIIVGESIVLPCQVASDPVLDVSFSWAFNGQLIAK 574

Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194
               H +L        L I +  L  AG+Y C    +V +    AIL V+ P
Sbjct: 575  GDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSAVAILIVKGP 625



 Score = 64.1 bits (149), Expect = 4e-08
 Identities = 69/261 (26%), Positives = 111/261 (42%), Gaps = 29/261 (11%)

Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713
           ECR    P+P  AWL  G++++  + I+V    D      VL +  +     G Y  VA 
Sbjct: 368 ECRANGKPKPSYAWLKNGQQLLSGDRITV---ED-----GVLSVPALALSDAGMYQCVAE 419

Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNN 772
           N+ G   +  V ++      P      L++++  + G +V L  +    P  +I W K N
Sbjct: 420 NKHG--VIYFVAELMVLASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGN 477

Query: 773 KPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829
            P+     +   SDG      + K     D G YT  A N  G++ T+  + V +PT   
Sbjct: 478 LPIHINDRITLSSDGTLRLANVSK----SDAGGYTCFARNRFGMSSTTGRLLVTDPTRIT 533

Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPV--PSITWYRNNEIISPSETITQNFDGEN 887
             P        EI V E  +I L  +V  +PV   S +W  N ++I+  +   +   G  
Sbjct: 534 QGP-----ADMEIIVGE--SIVLPCQVASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRT 586

Query: 888 I-ELVITNVDSEIDSGDYKCV 907
             +L+I N+     +G Y CV
Sbjct: 587 AGDLMIRNIQL-YHAGKYICV 606



 Score = 60.5 bits (140), Expect = 5e-07
 Identities = 112/534 (20%), Positives = 193/534 (36%), Gaps = 47/534 (8%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-------------VVEFPPKI-VDYEREYR 1298
            L I K    D   YTCV+ +  S TK KV+             + E+ PKI V++     
Sbjct: 211  LYIAKVEPSDVGNYTCVVTN--SVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVS 268

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
              RGS VTL       P P   W   + +      +K  +   +A L I   +  D G Y
Sbjct: 269  AARGSTVTLECFALGNPVPEITWKRANGVPFP---SKVKMKYSNAVLEIPSFQQDDTGGY 325

Query: 1359 KLRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            +   EN  G       +    KP      K   L I+     + W+   N        ++
Sbjct: 326  ECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEE---RLHWECRANGKPKPSYAWL 382

Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476
               Q++ + + I+V++      S+  L  + +  ++  A N+  +       E   +   
Sbjct: 383  KNGQQLLSGDRITVEDGV---LSVPALALSDAGMYQCVAENKHGV--IYFVAELMVLASP 437

Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXX 1535
                   +   LK    +    + L C     P   + W +    +    + T  +    
Sbjct: 438  PDFTGNLLRALLK---AKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSDGTL 494

Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595
                        Y C A N  G   T+  + +     IT    D++    VG+  ++   
Sbjct: 495  RLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDPTRITQGPADMEII--VGESIVLPCQ 552

Query: 1596 IEGIPPPEVI--WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            +   P  +V   W  NG  + + D  + +        + I+ ++  H+ KY         
Sbjct: 553  VASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVE 612

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
            + S    L V   PS P+  V + E++  +  + W    D+G   +  Y ++   P    
Sbjct: 613  SLSAVAILIVKGPPSPPDS-VTVEEVTDSTAQLAWSRGRDNGS-PIVNYFVQTRTPFTVG 670

Query: 1713 WIKVADV----DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762
            W +V  V    D +  T  +  LN   EY FRV+A+N VG     E  P+ ++T
Sbjct: 671  WQRVNTVPEIIDGNTLTATVVDLNAWVEYEFRVLARNSVGVG---EPSPVSVRT 721



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 5/92 (5%)

Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV----GG 1920
            PPS P +  V E T  +  L W+    NG SPI NY ++ +T     W ++ TV     G
Sbjct: 625  PPSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNYFVQTRTPFTVGWQRVNTVPEIIDG 683

Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952
            +     + ++    E  FR+ A N+VGV  P+
Sbjct: 684  NTLTATVVDLNAWVEYEFRVLARNSVGVGEPS 715



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+TV  EC+ + YP   I W +    I  +    +  D     TL +  V   DAG +TC
Sbjct: 454 GTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSD----GTLRLANVSKSDAGGYTC 509

Query: 584 VAKNAAGFASSTTELIVEAP 603
            A+N  G +S+T  L+V  P
Sbjct: 510 FARNRFGMSSTTGRLLVTDP 529



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 29/75 (38%), Positives = 38/75 (50%), Gaps = 4/75 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GSTV  EC   G P P+ITW R   +  PS+  +M Y +   A L I     +D G + C
Sbjct: 272 GSTVTLECFALGNPVPEITWKRANGVPFPSK-VKMKYSN---AVLEIPSFQQDDTGGYEC 327

Query: 584 VAKNAAGFASSTTEL 598
           VA+N  G   +T  L
Sbjct: 328 VAENRMGKNMATGRL 342



 Score = 46.4 bits (105), Expect = 0.009
 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 6/91 (6%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV----DV 2021
            PSPP + + +  V  +    +W     D G+P++ Y +  R      W  V  V    D 
Sbjct: 626  PSPPDS-VTVEEVTDSTAQLAWSRGR-DNGSPIVNYFVQTRTPFTVGWQRVNTVPEIIDG 683

Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052
            NTL   + DL+    Y  R+ ARN +G+ EP
Sbjct: 684  NTLTATVVDLNAWVEYEFRVLARNSVGVGEP 714


>UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome
            shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15
            SCAF14992, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1790

 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 102/411 (24%), Positives = 163/411 (39%), Gaps = 31/411 (7%)

Query: 1548 YKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPP 1601
            Y+C+A N  G   +S     V  +++   ++     +   H++  G    +T V  G P 
Sbjct: 23   YECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGGSVNITCVAVGSPM 82

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            P V W      L  + E  I      +V+ +  ++ S  + YT  A ++ G       + 
Sbjct: 83   PYVKWMLGAEDLTPEDEMPIGR----NVLELNGVRES--ANYTCMAMSSLGVIEAVAQVL 136

Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721
            V   P KP G  I+ E +  SVTI W    D G  +   Y I ++        K   VD 
Sbjct: 137  VKTLP-KPPGTPIVTETTATSVTITW----DSGNPDPVSYYIIQYRAKGPE-SKYETVDS 190

Query: 1722 DVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780
               T Y I  L  N EY  RV A N +G  +   S  +  +T    P+          I 
Sbjct: 191  ITTTRYSIGGLYPNTEYEIRVSAFNSIG--QGPPSARVEARTGEQAPASPPRNVQAHIIS 248

Query: 1781 NESVYITW-FPSEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837
              +V + W  P E NG      + Y ++  +   +W+           IQ L  + TY  
Sbjct: 249  QNTVMVRWEEPEEPNGQVKGYRVYYTMDPSRPMNEWQIHNVQDSVITTIQNLVTSETYTI 308

Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897
            ++ A   +G   P++  D + +      P QP  F V   T  S+ L W    +  G  I
Sbjct: 309  QVLAFTSVGDG-PFS--DPVHVKVMPGVPGQPGKFKVGRVTDTSIELTWEPAYTKEG--I 363

Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948
             NY + +K VK  S  K+    G  + + +E +K   E  F ++A +  G+
Sbjct: 364  VNYELLYKPVKFGSLEKLTF--GPRNSYTVEGLKPNTEYSFSLAAISNKGI 412



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 21/228 (9%)

Query: 1253 LIIRKCTEDDQCEYTCVLLDAK-----STTKLKV----EVVEFPPKIVDYEREYRIKRGS 1303
            L I    E DQ +Y CV  +++     S   L V    EV    P+       + I  G 
Sbjct: 10   LQIENSEETDQGKYECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGG 69

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
             V +       P P  +W++ ++ +       P  +       ++     ++  Y     
Sbjct: 70   SVNITCVAVGSPMPYVKWMLGAEDLT------PEDEMPIGRNVLELNGVRESANYTCMAM 123

Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQ-E 1421
            ++ G  +    V +   P PPG P + E  ++S+ I WD    +GN   + YY+++Y+ +
Sbjct: 124  SSLGVIEAVAQVLVKTLPKPPGTPIVTETTATSVTITWD----SGNPDPVSYYIIQYRAK 179

Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
               +++ +V +IT T+ SI  L  N+ Y  R  A N +     S   E
Sbjct: 180  GPESKYETVDSITTTRYSIGGLYPNTEYEIRVSAFNSIGQGPPSARVE 227



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 86/415 (20%), Positives = 152/415 (36%), Gaps = 23/415 (5%)

Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499
            I+N +     ++   A N   +  +S    Y + ++E +  SP       N    P   +
Sbjct: 12   IENSEETDQGKYECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGGSV 71

Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
             +TC+  G P P V W    + L         R               Y C+A +  G +
Sbjct: 72   NITCVAVGSPMPYVKWMLGAEDLTPEDEMPIGR--NVLELNGVRESANYTCMAMSSLGVI 129

Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKE 1618
            E    V ++  P        + +         VT   +   P  V +Y    + +  + +
Sbjct: 130  EAVAQVLVKTLPK-PPGTPIVTETTATS----VTITWDSGNPDPVSYYIIQYRAKGPESK 184

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-PSKPEGPVIM 1675
            Y       T+   I  L  +   +  + A N+ G    S  V  +  ++ P+ P   V  
Sbjct: 185  YETVDSITTTRYSIGGLYPNTEYEIRVSAFNSIGQGPPSARVEARTGEQAPASPPRNVQA 244

Query: 1676 REISRESVTIEWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732
              IS+ +V + W+ P +  G        Y ++   P  N W ++ +V   V T  IQ L 
Sbjct: 245  HIISQNTVMVRWEEPEEPNGQVKGYRVYYTMDPSRP-MNEW-QIHNVQDSVIT-TIQNLV 301

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792
             +  Y  +V+A   VG  +   S+P+ +K    VP            D  S+ +TW P+ 
Sbjct: 302  TSETYTIQVLAFTSVG--DGPFSDPVHVKVMPGVPGQPGKFKVGRVTDT-SIELTWEPAY 358

Query: 1793 KNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
               G  I++Y++  K  +    +           ++ L  NT Y F + A +  G
Sbjct: 359  TKEG--IVNYELLYKPVKFGSLEKLTFGPRNSYTVEGLKPNTEYSFSLAAISNKG 411



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 69/304 (22%), Positives = 115/304 (37%), Gaps = 36/304 (11%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           + P FS  P    +  G  + + C  V  P P + W+   E++ P        E +M + 
Sbjct: 52  VSPRFSILPSNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDEMPIG 103

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749
            +VL++  V+  +   YT +A++  G       + +KT  K P  P V E   + +    
Sbjct: 104 RNVLELNGVR--ESANYTCMAMSSLGVIEAVAQVLVKTLPKPPGTPIVTETTATSVTITW 161

Query: 750 ESVILSAQVVGNPRPT---ITWCKNNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYT 804
           +S        GNP P    I   +   P     T     T  +SI  L P     E    
Sbjct: 162 DS--------GNPDPVSYYIIQYRAKGPESKYETVDSITTTRYSIGGLYP---NTEYEIR 210

Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
           + A NS G    SA +      +  A PP    R  +  +  + T+ +       P   +
Sbjct: 211 VSAFNSIGQGPPSARVEARTGEQAPASPP----RNVQAHIISQNTVMVRWEEPEEPNGQV 266

Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDY--KCVASNSAGKSSHGARV 921
             YR    + PS  + + +   N+ + VIT + + + S  Y  + +A  S G       V
Sbjct: 267 KGYRVYYTMDPSRPMNE-WQIHNVQDSVITTIQNLVTSETYTIQVLAFTSVGDGPFSDPV 325

Query: 922 TIDV 925
            + V
Sbjct: 326 HVKV 329


>UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precursor;
           n=48; Euteleostomi|Rep: Neuronal cell adhesion molecule
           precursor - Mus musculus (Mouse)
          Length = 1256

 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 86/330 (26%), Positives = 145/330 (43%), Gaps = 33/330 (10%)

Query: 633 PPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
           PPTF + +    + +E  G+ + LEC    +P P I W+ K + ++P      A  +   
Sbjct: 261 PPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWI-KEDGMLP------ANRTFYR 313

Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749
            +   L+IT+V +   G Y  +A N  G     I + +K     P  ++ P +++++  G
Sbjct: 314 NFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAA---PYWIVAP-QNLVLSPG 369

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVK-AL--PT-KSDGDTHSITILKPKKVKDEGVYTL 805
           E+  L  +  GNP+P I+W  N  P++ AL  P+ K DGDT    I    +     VY  
Sbjct: 370 ENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKIDGDT---IIFSNVQESSSAVYQC 426

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSI 864
            A N  G    +A + V       AEPP  +     +  V       L      +P+P+I
Sbjct: 427 NASNKYGYLLANAFVNV------LAEPPRILTSANTLYQVIANRPALLDCAFFGSPMPTI 480

Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
            W++  +  +  E I    D   +E+ +   DS   +G Y CVA N  G + +   V ++
Sbjct: 481 EWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDS---TGTYTCVARNKLGMAKN--EVHLE 535

Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH 954
           ++  T +    +    + G  V  EC+  H
Sbjct: 536 IKDPTRIIKQPEYAVVQRGSKVSFECRVKH 565



 Score = 91.1 bits (216), Expect = 3e-16
 Identities = 130/588 (22%), Positives = 222/588 (37%), Gaps = 56/588 (9%)

Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAF 1553
            N    L C F G P P + W++  K     +  Y   +                Y C+A 
Sbjct: 463  NRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVAR 522

Query: 1554 NDHGEVETSCVVGIQQKPVITISNED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611
            N  G  +    + I+    I    E   +++  KV  E  V      IP   ++W K+  
Sbjct: 523  NKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPT--IMWLKDNG 580

Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV--------- 1662
            +L ND+ ++ T K+    + + ++K      YT  A+ T  ++S    L+V         
Sbjct: 581  ELPNDERFS-TDKDH---LVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAP 636

Query: 1663 -YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP--DNNRWIKVADV 1719
             YD P+ P    +  ++ + SV + W P  DD    +TK+ IE  +   D   W   A+V
Sbjct: 637  IYDVPNPPFDLELTNQLDK-SVQLTWTPG-DDNNSPITKFIIEYEDAMHDAGLWRHQAEV 694

Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXX 1778
                +T    KL+    Y FRV+A+N +G S   E SE  + K A   P           
Sbjct: 695  S-GTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEASEQYLTKAA--EPDQNPMAVEGLG 751

Query: 1779 IDNESVYITWFP-SEKNGGSPIIDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTY 1835
             + +++ ITW P +      P + YKV  +Q+    +W            +        Y
Sbjct: 752  TEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPY 811

Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNG 1893
              ++ A N++G + P  +      G+ L P   P N  VS   S    + W    P+S  
Sbjct: 812  LIKVQALNDVGFA-PEPAAVMGHSGEDL-PMVAPGNVRVSVVNSTLAEVHWDPVPPKSVR 869

Query: 1894 GSPITNYIIEFKTVKGKSWT------KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947
            G      I  +KT             KI+T  G+     +  ++        +   N  G
Sbjct: 870  GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKG 929

Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNIAI 2005
                +  +        T    P+AP  +++V   +  +   W  P    G  L  Y +  
Sbjct: 930  EGPASTDRGFH-----TPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYILQY 983

Query: 2006 RDVTKTMWMEVG-----KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048
            + +  T   E+G     K+  N  ++ +++L+ +  Y    YA+  +G
Sbjct: 984  QPINST--HELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVG 1029



 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 140/646 (21%), Positives = 256/646 (39%), Gaps = 72/646 (11%)

Query: 633  PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            PPT +++ PK   +D   +I+++C     P P  +W   G     D++  V ++      
Sbjct: 39   PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTL 98

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750
               +      +  EG Y   A N  G A S  IV++     + P    E L+ ++++ G+
Sbjct: 99   VINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKERLEPIVLQNGQ 155

Query: 751  SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803
            S++L  +  +G P   I W  N+   + LP         +GD +   +L P+  +++ + 
Sbjct: 156  SLVLPCRPPIGLPPAIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 212

Query: 804  TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843
              +  +++ I +    +  VI+V+E           TE          PP F+      +
Sbjct: 213  YARFNHTQTIQQKQPISLKVISVDELNDTIAANLSDTEFYGAKSSKERPPTFLTPEGNES 272

Query: 844  VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900
             KE  +G +  +  +    P P I W + + ++  + T  +NF      L IT+V SE D
Sbjct: 273  HKEELRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNF---KKTLQITHV-SEAD 328

Query: 901  SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960
            SG+Y+C+A N+ G   H   VT+       V          E  T+I     +      W
Sbjct: 329  SGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISW 388

Query: 961  YHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKET 1015
              N   I   +D      +G                V +C   ++      +  + V   
Sbjct: 389  LTNGVPIEIALDDPSRKIDGDTIIFSNVQESSS--AVYQCNASNKYGYLLANAFVNVLAE 446

Query: 1016 IPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073
             P  +      ++V     A+L+     S    + W +  +     ++ Y     G    
Sbjct: 447  PPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNG---T 503

Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130
            L I        G Y+C+ R++   A+  V   ++ P  II + +   V +G+K +FE  +
Sbjct: 504  LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRV 563

Query: 1131 TKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183
                 L   + W KD  E+   N  + + D  K  L + D   DD G Y+C     + ++
Sbjct: 564  KHDHTLIPTIMWLKDNGEL--PNDERFSTD--KDHLVVSDVKDDDGGTYTCTANTTLDSA 619

Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229
              +A+L V  P+       P + +     D  LT ++ D+++ +TW
Sbjct: 620  SASAVLRVVAPT---PTPAPIYDVPNPPFDLELTNQL-DKSVQLTW 661



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 173/815 (21%), Positives = 302/815 (37%), Gaps = 84/815 (10%)

Query: 1013 KETIPEFIRKLQDFEVKEKDVA-ILEVEINSE---TADVVWERDGEIIKPKKNKYDFEKR 1068
            KE  P F+    +   KE+    +L +E  +E   T  + W ++  ++   +  Y    R
Sbjct: 258  KERPPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFY----R 313

Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKAT 1125
               + L I + S  D G Y CI ++       T+   V+  P  I   QN  ++ G   T
Sbjct: 314  NFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGT 373

Query: 1126 FEIELTKGDALVR--WFKDGSEIQFS-NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
              I    G+   R  W  +G  I+ + +     IDG    +   +     +  Y C   N
Sbjct: 374  L-ICRANGNPKPRISWLTNGVPIEIALDDPSRKIDG--DTIIFSNVQESSSAVYQCNASN 430

Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY-KKKSVIE---D 1238
             K   +L      +N  L  P  IL  ANT  Y  +      LD  ++      IE    
Sbjct: 431  -KYGYLLA--NAFVN-VLAEPPRILTSANT-LYQVIANRPALLDCAFFGSPMPTIEWFKG 485

Query: 1239 TEKFTLISDV----KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDY 1293
            T+   L  D+       TL I    +D    YTCV  +     K +V + ++ P +I+  
Sbjct: 486  TKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQ 545

Query: 1294 EREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351
                 ++RGS V+    V +     P   W+ ++  +   +      D     L +  V+
Sbjct: 546  PEYAVVQRGSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFSTDKDH----LVVSDVK 601

Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL----------DKPSPPGKPNILEIDSSSINICW 1401
            + D G Y          A     + ++          D P+PP    +      S+ + W
Sbjct: 602  DDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTW 661

Query: 1402 DEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNE 1458
              P +  NS I  +++EY++   D   W     ++ TQT+ Q  L    +Y FR  A N 
Sbjct: 662  T-PGDDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENS 720

Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP------QPK 1512
            +  S  SE +E Y        Q+P     ++ + TEP+  +       G        Q K
Sbjct: 721  IGRSMPSEASEQYLTKAAEPDQNPMA---VEGLGTEPDNLVITWKPLNGFQSNGPGLQYK 777

Query: 1513 VTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-EVETSCVVGIQQKP 1571
            V+W +     +       N                 K  A ND G   E + V+G   + 
Sbjct: 778  VSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDVGFAPEPAAVMGHSGED 837

Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-- 1629
            +  ++  +++    V +  L     + +PP  V  +  G ++   K  + + + +  +  
Sbjct: 838  LPMVAPGNVRV--SVVNSTLAEVHWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEK 895

Query: 1630 -IRIKELKRSHS--------SKY--TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678
             I   +  ++H         S Y   +   N  G          +     P  P  ++ +
Sbjct: 896  KILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIV 955

Query: 1679 --SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET----YCIQKLN 1732
              + +S+T+EW PP    G+ LT+Y ++ ++P N+       VD  +      + ++ LN
Sbjct: 956  NPTLDSLTLEWDPPSHPNGI-LTEYILQ-YQPINSTHELGPLVDLKIPANKTRWTLKNLN 1013

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767
             +  Y F   AQ  VG    +  E I       +P
Sbjct: 1014 FSTRYKFYFYAQTSVGPGSQITEEAITTVDEAGIP 1048



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 51/191 (26%), Positives = 85/191 (44%), Gaps = 8/191 (4%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923
            P+ P +  ++    +SV L WT P  +  SPIT +IIE++     +  W     V G+  
Sbjct: 641  PNPPFDLELTNQLDKSVQLTWT-PGDDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQT 699

Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983
               ++ +       FR+ AEN++G S+P+E+    L K A     P A   +     N+V
Sbjct: 700  TAQLK-LSPYVNYSFRVMAENSIGRSMPSEASEQYLTKAAEPDQNPMAVEGLGTEPDNLV 758

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042
            +T      +    P L Y ++ R       W  V  V  N  K+ +        Y+I++ 
Sbjct: 759  ITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSV--VVANVSKYIVSGTPTFVPYLIKVQ 816

Query: 2043 ARNEIGLS-EP 2052
            A N++G + EP
Sbjct: 817  ALNDVGFAPEP 827



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 10/284 (3%)

Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448
            I  +D+S   +   E  + G +  +Y+     E    ++I       TQT IQ  +  S 
Sbjct: 172  IFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQKQPISL 230

Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDIELTCIF 1505
                   +N+   ++ S+T E+Y   K +K + PT   P  N + +       + L CI 
Sbjct: 231  KVISVDELNDTIAANLSDT-EFYGA-KSSKERPPTFLTPEGNESHKEELRGNVLSLECIA 288

Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
             G+P P + W ++   L   +  Y N +               Y+CIA N  G V  +  
Sbjct: 289  EGLPTPIIYWIKEDGMLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGAVHHTIS 348

Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624
            V ++  P   ++ +++      G+   +     G P P + W  NG  +E   + + + K
Sbjct: 349  VTVKAAPYWIVAPQNLVL--SPGENGTLICRANGNPKPRISWLTNGVPIEIALD-DPSRK 405

Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668
                 I    ++ S S+ Y   ASN  G       + V  +P +
Sbjct: 406  IDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPR 449



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G+ +  EC  EG P P I W ++  ++  ++ F   +      TL I  V   D+G + C
Sbjct: 279 GNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKK----TLQITHVSEADSGNYQC 334

Query: 584 VAKNAAGFASSTTELIVEA 602
           +AKNA G    T  + V+A
Sbjct: 335 IAKNALGAVHHTISVTVKA 353



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           +C   G P P I WF+ T      +D  + +D+    TL I     +  GT+TCVA+N  
Sbjct: 469 DCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDN---GTLEIPVAQKDSTGTYTCVARNKL 525

Query: 590 GFASSTTELIVEAP 603
           G A +   L ++ P
Sbjct: 526 GMAKNEVHLEIKDP 539



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE----WISVK-NITK 1435
            PS P    I+     S+ + WD P +  N  +  Y+++YQ I++T      + +K    K
Sbjct: 946  PSAPSSLKIVNPTLDSLTLEWDPPSHP-NGILTEYILQYQPINSTHELGPLVDLKIPANK 1004

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484
            T+ +++NL  ++ Y+F  YA   V    +  T E    + E  I  P V
Sbjct: 1005 TRWTLKNLNFSTRYKFYFYAQTSVG-PGSQITEEAITTVDEAGIPPPDV 1052



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%)

Query: 524 GSTVQFECQVEGYPR--PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581
           GS V FEC+V+      P I W +    +   + F    D D+   LV+ +V  +D GT+
Sbjct: 554 GSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFST--DKDH---LVVSDVKDDDGGTY 608

Query: 582 TCVAKNAAGFASSTTELIVEAP 603
           TC A      AS++  L V AP
Sbjct: 609 TCTANTTLDSASASAVLRVVAP 630


>UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 588

 Score = 90.6 bits (215), Expect = 4e-16
 Identities = 95/460 (20%), Positives = 169/460 (36%), Gaps = 40/460 (8%)

Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353
            +R   +    D ++       P PN  W+       K   +  +  + SA L++ K++  
Sbjct: 9    DRSRDVAEDKDFSITCSASGRPAPNVTWV------NKTSGSPVAHGTGSAILSLLKIQRH 62

Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413
             AG+Y+ +  N+     +  + TI    +    P I  I ++++          G +  +
Sbjct: 63   QAGVYQCQATNDVKRGAITQDFTI----NVQYPPEITPIQNTTVR--------AGETITL 110

Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
               V      +  W    +   T  ++ N    +      Y    V+I   +  T+    
Sbjct: 111  TCAVAGNPTPSVSWSKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVST 170

Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533
                K +   +         E    ++L+CI  G P P VTW RDG  +      Y +  
Sbjct: 171  YVIVKYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTSVYYSD-- 228

Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593
                          Y C A N+ G    +  V +  KP +  S  +    ++      + 
Sbjct: 229  -----SVTRSEAGTYTCTATNEMGSDTNTVQVTVNYKPEMASSTTNTSSWNR--KVLSLQ 281

Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS-SKYTIEASNTAG 1652
                G+P P++ WYK G +        I+  +    +++   + S    +Y   ASN  G
Sbjct: 282  CKARGVPLPQITWYKPGGQPITAGVSPISGGQ----LQVTTTQDSGDYGQYKCRASNLLG 337

Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712
            +    + +  +  P  P   +I+  I   S+ + W PP  DGG  +  Y +E  +P    
Sbjct: 338  SVGRLIYVTQWFSPGPP--IIIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEV-DPAKPP 394

Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752
               VA          I  L +N EY  +V A+N VG+ EA
Sbjct: 395  REGVAG-----GPVVISGLTKNTEYTVKVTARNVVGYGEA 429



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 64/285 (22%), Positives = 115/285 (40%), Gaps = 37/285 (12%)

Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
           +++ V E  D  + C     P P++ W+ K            AI          L +  +
Sbjct: 10  RSRDVAEDKDFSITCSASGRPAPNVTWVNKTSGSPVAHGTGSAI----------LSLLKI 59

Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760
           ++ Q G Y   A N     ++     I    + PP+ I P+++  VR GE++ L+  V G
Sbjct: 60  QRHQAGVYQCQATNDVKRGAITQDFTINV--QYPPE-ITPIQNTTVRAGETITLTCAVAG 116

Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819
           NP P+++W K           S   T      +    K E G Y   A N   ++  +  
Sbjct: 117 NPTPSVSWSKAG---------SGQSTGGNVFNEAGATKAETGQYVCTAVNI--VSGNTQT 165

Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            TV        +P +  N   +   +  G++KL       P P +TW R+  ++SP    
Sbjct: 166 KTVSTYVIVKYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSP---- 221

Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
           T  +  +++        +  ++G Y C A+N  G  ++  +VT++
Sbjct: 222 TSVYYSDSV--------TRSEAGTYTCTATNEMGSDTNTVQVTVN 258



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 12/75 (16%)

Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585
           +++  C  +GYP P +TW R   ++ P+    +YY D          V   +AGT+TC A
Sbjct: 195 SLKLSCISDGYPAPMVTWSRDGVVVSPT---SVYYSD---------SVTRSEAGTYTCTA 242

Query: 586 KNAAGFASSTTELIV 600
            N  G  ++T ++ V
Sbjct: 243 TNEMGSDTNTVQVTV 257



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 68/272 (25%), Positives = 96/272 (35%), Gaps = 39/272 (14%)

Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704
           V  G  I L C +   P P ++W   G              S      +V       K +
Sbjct: 102 VRAGETITLTCAVAGNPTPSVSWSKAG--------------SGQSTGGNVFNEAGATKAE 147

Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNP 762
            G Y   AVN     +    +      K  P +I   P +++    G S+ LS    G P
Sbjct: 148 TGQYVCTAVNIVSGNTQTKTVSTYVIVKYKPSIIANSPYQTVNETTG-SLKLSCISDGYP 206

Query: 763 RPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            P +TW ++   V       SD  T S          + G YT  A N  G    +  +T
Sbjct: 207 APMVTWSRDGVVVSPTSVYYSDSVTRS----------EAGTYTCTATNEMGSDTNTVQVT 256

Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
           V      N +P +  +     +   K  + L  +    P+P ITWY+      P      
Sbjct: 257 V------NYKPEMASSTTNTSSWNRK-VLSLQCKARGVPLPQITWYKPGG--QPITAGVS 307

Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
              G  ++ V T  DS  D G YKC ASN  G
Sbjct: 308 PISGGQLQ-VTTTQDSG-DYGQYKCRASNLLG 337



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838
            I+  S+ + W P   +GGSP+IDYKVE+       +           I  L+ NT Y  +
Sbjct: 361  IEASSIKVNWAPPSSDGGSPVIDYKVEVDPAKPPREGVAGGPVV---ISGLTKNTEYTVK 417

Query: 1839 IYARNEIG 1846
            + ARN +G
Sbjct: 418  VTARNVVG 425



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 36/133 (27%), Positives = 55/133 (41%), Gaps = 11/133 (8%)

Query: 735 PQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793
           P    PL +S  V + +   ++    G P P +TW   NK     P      +  +++LK
Sbjct: 2   PAFNPPLDRSRDVAEDKDFSITCSASGRPAPNVTWV--NK-TSGSPVAHGTGSAILSLLK 58

Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853
            ++    GVY  +A N       +   T+      N + P  I   Q  TV+   TI L 
Sbjct: 59  IQR-HQAGVYQCQATNDVKRGAITQDFTI------NVQYPPEITPIQNTTVRAGETITLT 111

Query: 854 ARVTRNPVPSITW 866
             V  NP PS++W
Sbjct: 112 CAVAGNPTPSVSW 124



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 74/352 (21%), Positives = 129/352 (36%), Gaps = 44/352 (12%)

Query: 844  VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903
            V E     +    +  P P++TW  N    SP    T    G  I L +  +     +G 
Sbjct: 14   VAEDKDFSITCSASGRPAPNVTWV-NKTSGSPVAHGT----GSAI-LSLLKIQRH-QAGV 66

Query: 904  YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWY 961
            Y+C A+N   + +     TI+V+    +  +Q +     G+T+ L C  +   T S  W 
Sbjct: 67   YQCQATNDVKRGAITQDFTINVQYPPEITPIQNT-TVRAGETITLTCAVAGNPTPSVSW- 124

Query: 962  HNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI 1020
               K  SG      +  E               V ++    + +  ST ++VK   P  I
Sbjct: 125  --SKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVSTYVIVKYK-PSII 181

Query: 1021 RKLQDFEVKEKDVAILEVEINSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077
                 ++   +    L++   S+      V W RDG ++ P                Y  
Sbjct: 182  AN-SPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTS------------VYYSD 228

Query: 1078 NTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132
            + +  + G Y+C   +E    + T +VT V   PE+ +   N   +  N+    ++   +
Sbjct: 229  SVTRSEAGTYTCTATNEMGSDTNTVQVT-VNYKPEMASSTTN--TSSWNRKVLSLQCKAR 285

Query: 1133 GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182
            G  L  + W+K G +   +  +     G+ Q     D    D G+Y C   N
Sbjct: 286  GVPLPQITWYKPGGQ-PITAGVSPISGGQLQVTTTQDS--GDYGQYKCRASN 334



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928
            P   +VS   + S+ + W  P S+GGSP+ +Y +E    K     +    GG V    I 
Sbjct: 353  PPIIIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEVDPAKP---PREGVAGGPV---VIS 406

Query: 1929 NIKEKDEIIFRISAENTVG 1947
             + +  E   +++A N VG
Sbjct: 407  GLTKNTEYTVKVTARNVVG 425



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 8/86 (9%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025
            P PP   + +  + ++ +  +W  P  DGG+P++ Y + + D  K     V    V    
Sbjct: 351  PGPPI--IIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEV-DPAKPPREGVAGGPV---- 403

Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSE 2051
              I  L++N  Y +++ ARN +G  E
Sbjct: 404  -VISGLTKNTEYTVKVTARNVVGYGE 428


>UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled
           protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to frazzled protein - Nasonia vitripennis
          Length = 1478

 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 87/339 (25%), Positives = 144/339 (42%), Gaps = 31/339 (9%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P F ++P+   V  G    L C+L    + +I WL   + ++ DE+    + S       
Sbjct: 133 PGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPS------G 186

Query: 694 VLKITNVKKFQEGTYTVVAVN-REGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVR 747
            L+I  V     G+Y   A    +   S    L ++T     GE  P  V +P   + + 
Sbjct: 187 ALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIE 246

Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805
           +  ++ L     GNP+P + W K+   +      S   T + + L  K V  +D G Y  
Sbjct: 247 KS-TITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQC 305

Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
           +A+N     +  A + V+ P       P FI R Q+    E   ++    +   P P IT
Sbjct: 306 RAKNDIDTLDAVAEVVVQVP-------PRFIKRPQDKEASEHQELEFECEIYGKPPPLIT 358

Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925
           W +N E+I  S    Q  +G N+++   N    ID+G ++C+ +N AG     AR+TI  
Sbjct: 359 WLKNGEVIKLS-NYWQLTNGYNLKI---NGLLNIDAGIFQCMGTNPAGSVQASARLTIHQ 414

Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYH 962
            K    +     + +  GK V  + + SH V  ++ W H
Sbjct: 415 PKKE--RKGPGRHRSANGKPVCKK-RLSHKVLSNSTWQH 450



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 103/433 (23%), Positives = 160/433 (36%), Gaps = 30/433 (6%)

Query: 1649 NTAGTSSVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707
            N  G S+ E+ ++ + D PS P   V +      S+ I W+PP +     +T Y I    
Sbjct: 701  NGPGASTSEIRVRTFGDVPSNPPN-VTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRP 759

Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN-----PVGFSEALESEPIVIK- 1761
             D      +   D +   Y + +L +N  Y  RV A N     P G SE  E E      
Sbjct: 760  TDRRIHSSLITTDGNARYYVLNRLQKNISYQVRVCAFNVNGTGPTGCSEWQEVETYENDL 819

Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXX 1820
            +  DVPS           D  S+ + W P  KN    +  Y +   K    ++K      
Sbjct: 820  SESDVPSAPTNLKTNPMSD--SIDVRWGP-PKNQSIKVRGYVLTWGKGIPDEYKKVLDGK 876

Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT------IGKTLTPPSQPRNFVV 1874
                +I  L  N+ Y   + A+NE G  L    + + T          LTPP   +  V+
Sbjct: 877  QRYYQIDNLEPNSDYVITLRAKNEAGEGLQVYENVRTTEKTSAESAAPLTPPVGLKTVVM 936

Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934
            S ST   V L WT+ ++   +    YI+ + +    S  +      +     I ++K   
Sbjct: 937  SSST---VVLHWTDSKNQHVTDNRYYIVRYTSYHRSSNQRYKYYNTTDLNCMIHDLKPNT 993

Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEW 1992
            E  F +      G      S  V  +     PS P   L ++ +      V+  W  P+ 
Sbjct: 994  EYEFTVKV--VKGRRESPWSMVVMNKTLEAKPSSPPRDLTVQSIDEYPKSVLLRWLPPKL 1051

Query: 1993 DGGAPLLGYNIAI---RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
              G  + GY I      +  +  W     V   T      +L  + TY  +I ARN  G 
Sbjct: 1052 SNG-DINGYIIRYTTDNNKDERDWKTEAFVGDKTEFVLPAELQPSTTYYFKIGARNAKGY 1110

Query: 2050 SEPLESDEPFKVI 2062
              P  S  P++ +
Sbjct: 1111 G-PFSSTVPYRTL 1122



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 91/360 (25%), Positives = 146/360 (40%), Gaps = 36/360 (10%)

Query: 861  VPSITWYRNNEIISPSETITQNFDG--ENIELVITNVDSEIDSGDYKCVAS-NSAGKSSH 917
            +P ITW    E   P   I   +    EN  L I+  + E   G Y+CVAS  + G  + 
Sbjct: 66   LPVITW--RTEDGQPINFIGDKYRSQLENGSLYISAANQE-SIGSYQCVASIENVGAIAS 122

Query: 918  GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975
               V        F +  Q +     G+   L C+  TS  V+ +W  +++ +   + R  
Sbjct: 123  RTAVVKLASLPGFDREPQDTM-VYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMT 181

Query: 976  IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVK-------ETIPEFIRKL 1023
            I                DVG  +C           T   L ++       E++P F+ K 
Sbjct: 182  ILPS--GALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKP 239

Query: 1024 QDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082
             +    EK    LE   N     +V W +DG  I        ++       L I++ +  
Sbjct: 240  FNQVAIEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVA-ASSLMIKDVTEE 298

Query: 1083 DEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVR 1138
            D G Y C  +++  T +     VV++PP  I R Q+++ ++  +  FE E+  K   L+ 
Sbjct: 299  DNGSYQCRAKNDIDTLDAVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLIT 358

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194
            W K+G  I+ SN+ QLT       LKI      DAG + C      G+ + +A LT+ +P
Sbjct: 359  WLKNGEVIKLSNYWQLT---NGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415



 Score = 70.1 bits (164), Expect = 6e-10
 Identities = 80/377 (21%), Positives = 147/377 (38%), Gaps = 19/377 (5%)

Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737
            ++   V + W+ P    G E++ Y I   +    R  ++    R+  T  I  L     Y
Sbjct: 539  VNSRFVALRWQEPEITSG-EISNYLIYYKQEGFERE-RIERTPREETTVTISGLQPGTTY 596

Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGG 1796
            +FR +A      S + +   +  ++  +VPS            ++S+ ++W  P+  NG 
Sbjct: 597  LFRAVANVSNVLSASSKVLELTTESEPNVPSHPLNLRGWPT-SSQSIMLSWEEPTTTNGR 655

Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856
              I  Y +    EG   +           +  L     Y   + A N+ G   P  S  +
Sbjct: 656  --ISGYLITYA-EGDYEELNRNTTNTSYELTGLKPYREYNIWVQAINDNG---PGASTSE 709

Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916
            I +      PS P N  +    + S+ ++W  P       IT Y I ++    +  + ++
Sbjct: 710  IRVRTFGDVPSNPPNVTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRPTDRRIHSSLI 769

Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT---ESQSVR-LEKHATVPSPPTAP 1972
            T  G+   + +  +++      R+ A N  G   PT   E Q V   E   +    P+AP
Sbjct: 770  TTDGNARYYVLNRLQKNISYQVRVCAFNVNGTG-PTGCSEWQEVETYENDLSESDVPSAP 828

Query: 1973 LEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031
              ++    S+ +   WG P+ +    + GY +         + +V  +D     + I +L
Sbjct: 829  TNLKTNPMSDSIDVRWGPPK-NQSIKVRGYVLTWGKGIPDEYKKV--LDGKQRYYQIDNL 885

Query: 2032 SENHTYMIRIYARNEIG 2048
              N  Y+I + A+NE G
Sbjct: 886  EPNSDYVITLRAKNEAG 902



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 81/351 (23%), Positives = 136/351 (38%), Gaps = 27/351 (7%)

Query: 1047 VVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTV 1102
            + W   DG+ I    +KY  +       LYI   +    G Y C+   E+  A      V
Sbjct: 69   ITWRTEDGQPINFIGDKYRSQLENG--SLYISAANQESIGSYQCVASIENVGAIASRTAV 126

Query: 1103 VELP--PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGK 1159
            V+L   P      Q+  V  G  A    +L   D + ++W KD   +      ++TI   
Sbjct: 127  VKLASLPGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDES-RMTIL-P 184

Query: 1160 KQKLKIYDCDLDDAGEYSCEV---GNSKCT--AILTVEEPSINFTLRLPEFILVPANTDA 1214
               L+I +    D G Y C     G  + +  A L ++   I     +P F+  P N  A
Sbjct: 185  SGALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVA 244

Query: 1215 Y----LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267
                 +T+E     +   +V W K  + I+     +    V   +L+I+  TE+D   Y 
Sbjct: 245  IEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQ 304

Query: 1268 CVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326
            C   +   T     E VV+ PP+ +   ++       ++    +    P P   W+ N +
Sbjct: 305  CRAKNDIDTLDAVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGE 364

Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377
            +IK   + +    +   +L I  + N DAGI++    N  G       +TI
Sbjct: 365  VIKLSNYWQL---TNGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTI 412



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 5/126 (3%)

Query: 479 NYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538
           N + + Q +L+ K  +L +      E +SM P+FV K   +   + ST+  EC   G P+
Sbjct: 204 NASGFGQYRLSTKA-QLALQTSDIGEGESM-PVFVAKPFNQVAIEKSTITLECAANGNPK 261

Query: 539 PQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
           P++ W +  T+I   S D +  Y     ++L+I++V  ED G++ C AKN      +  E
Sbjct: 262 PEVYWLKDGTSIDLASLDSR--YQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVAE 319

Query: 598 LIVEAP 603
           ++V+ P
Sbjct: 320 VVVQVP 325



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 51/229 (22%), Positives = 85/229 (37%), Gaps = 10/229 (4%)

Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507
            SYR  A    +  +S  ++       I E +     V KP   +  E +  I L C   G
Sbjct: 200  SYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKST-ITLECAANG 258

Query: 1508 VPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXX--XYKCIAFNDHGEVETSC 1563
             P+P+V W +DG  +  A   + Y+                   Y+C A ND   ++   
Sbjct: 259  NPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVA 318

Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             V +Q  P      +D +       E      I G PPP + W KNG  ++    + +T 
Sbjct: 319  EVVVQVPPRFIKRPQDKEASEH--QELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTN 376

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672
                  ++I  L    +  +    +N AG+      L ++    + +GP
Sbjct: 377  GYN---LKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQPKKERKGP 422



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P F+++ + K   +   ++FEC++ G P P ITW +   +IK S     Y+   N   L 
Sbjct: 326 PRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSN----YWQLTNGYNLK 381

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           I  +   DAG F C+  N AG   ++  L +  P
Sbjct: 382 INGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 12/192 (6%)

Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
            +G+  T P  PRN  +    SR V L+W EPE   G  I+NY+I +K  +G    +I   
Sbjct: 521  LGEAGTLPLAPRNLSIGLVNSRFVALRWQEPEITSGE-ISNYLIYYKQ-EGFERERIERT 578

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-- 1976
                    I  ++     +FR  A   V   L   S+ + L   +  P+ P+ PL +R  
Sbjct: 579  PREETTVTISGLQPGTTYLFRAVA--NVSNVLSASSKVLELTTESE-PNVPSHPLNLRGW 635

Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036
               S  +M SW  P    G  + GY I   +     + E+ +   NT  + +  L     
Sbjct: 636  PTSSQSIMLSWEEPTTTNGR-ISGYLITYAEGD---YEELNRNTTNT-SYELTGLKPYRE 690

Query: 2037 YMIRIYARNEIG 2048
            Y I + A N+ G
Sbjct: 691  YNIWVQAINDNG 702



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 17/49 (34%), Positives = 27/49 (55%)

Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674
           A+++  +PP F K+P+ +   E  ++  EC +   P P I WL  GE I
Sbjct: 318 AEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVI 366



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 19/190 (10%)

Query: 1386 KP-NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQN 1442
            KP N + I+ S+I +   E    GN    +Y++ +   ID     S  + +  +   I++
Sbjct: 238  KPFNQVAIEKSTITL---ECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKD 294

Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTEPNEDIE 1500
            +    +  ++  A N++D  DA         + E  +Q P   +++P     +E ++++E
Sbjct: 295  VTEEDNGSYQCRAKNDIDTLDA---------VAEVVVQVPPRFIKRPQDKEASE-HQELE 344

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559
              C   G P P +TW ++G+ +K +      N                ++C+  N  G V
Sbjct: 345  FECEIYGKPPPLITWLKNGEVIKLSNYWQLTNGYNLKINGLLNIDAGIFQCMGTNPAGSV 404

Query: 1560 ETSCVVGIQQ 1569
            + S  + I Q
Sbjct: 405  QASARLTIHQ 414



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 1373 MNVTILDKPSPPGKPNILE---IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429
            + +T   +P+ P  P  L      S SI + W+EP  T N  I  Y++ Y E D  E   
Sbjct: 615  LELTTESEPNVPSHPLNLRGWPTSSQSIMLSWEEPTTT-NGRISGYLITYAEGDYEE--L 671

Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458
             +N T T   +  LK    Y     A+N+
Sbjct: 672  NRNTTNTSYELTGLKPYREYNIWVQAIND 700



 Score = 37.5 bits (83), Expect = 4.0
 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 11/133 (8%)

Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPS--------PPG 1385
            K  +D K     I  +E     +  LR +N  G    V  NV   +K S        PP 
Sbjct: 870  KKVLDGKQRYYQIDNLEPNSDYVITLRAKNEAGEGLQVYENVRTTEKTSAESAAPLTPPV 929

Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQNL 1443
                + + SS++ + W + +N   +   YY+V Y      + +     N T     I +L
Sbjct: 930  GLKTVVMSSSTVVLHWTDSKNQHVTDNRYYIVRYTSYHRSSNQRYKYYNTTDLNCMIHDL 989

Query: 1444 KTNSSYRFRAYAV 1456
            K N+ Y F    V
Sbjct: 990  KPNTEYEFTVKVV 1002



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 5/140 (3%)

Query: 1363 ENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421
            +N  G +  E+ V T  D PS P    I    ++SI I W+ P    N  I  Y + Y+ 
Sbjct: 700  DNGPGASTSEIRVRTFGDVPSNPPNVTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRP 759

Query: 1422 IDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETK 1478
             D     S+   +       +  L+ N SY+ R  A N V+ +  +  +E+ +V   E  
Sbjct: 760  TDRRIHSSLITTDGNARYYVLNRLQKNISYQVRVCAFN-VNGTGPTGCSEWQEVETYEND 818

Query: 1479 IQSPTVEKPLKNITTEPNED 1498
            +    V     N+ T P  D
Sbjct: 819  LSESDVPSAPTNLKTNPMSD 838


>UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Neural
            adhesion molecule L1.2.; n=1; Takifugu rubripes|Rep:
            Homolog of Brachydanio rerio "Neural adhesion molecule
            L1.2. - Takifugu rubripes
          Length = 1204

 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 141/689 (20%), Positives = 274/689 (39%), Gaps = 66/689 (9%)

Query: 830  AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889
            ++PP+     + IT      I L  +   NP P+  W ++  +I  S         E  E
Sbjct: 3    SQPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIR-SGLHLGTLKAEEEE 61

Query: 890  LVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL 948
             +      +   G Y+C ASN  G + +   +V ++ + V   K  Q   E+ EG+++IL
Sbjct: 62   PL------QQFEGHYRCYASNDYGTAMTQSVQVIVEAQPV-LPKQQQVHKESYEGESIIL 114

Query: 949  ECQTSHTVSTKWYH-----------NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997
             C    + +    H           +++ + G+D +                        
Sbjct: 115  SCNPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLYFSNLLRNDSRTDYMCNAQYLAA 174

Query: 998  KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER--DGEI 1055
            + I+ +   S  +V    + +  RK   F+      ++L +  +  T + + +     ++
Sbjct: 175  RTILTESVISLTVVPSNDVAQ-ARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTPKV 233

Query: 1056 IKPKKNKYDFEKRG----HIRKLYIRNTSVHDEGEYSCILRDES--CTAEVTV-VELPPE 1108
               KK+    E  G    H R  +  +  ++D+GEY C   +     T   TV VE  P 
Sbjct: 234  EWKKKDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAAPY 293

Query: 1109 IITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIY 1166
             + +  +Q  + G     + +        + W  +G  I +     + ++ G    L+  
Sbjct: 294  WVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILR-- 351

Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226
            D    D   Y CE  N   +A+L     +    + LP  IL    +D  L          
Sbjct: 352  DVVFADTAVYQCEATNKHGSALLN----TFLHVVELPPQILT---SDGLL--------YR 396

Query: 1227 VTWYKKKSVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285
            VT  + ++++ D E F +    +   TL+I +   DD   Y+C +    +   +   +  
Sbjct: 397  VT--EGRNILMDCEVFGSPRPHITCGTLVISEVDHDDAGVYSCSVKH-NNNVSINAHLEV 453

Query: 1286 FPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIV----NSKIIKKCKHTKPSIDS 1340
            +   ++    +  R  RG++  L   +   P+     +V      K++      K S+  
Sbjct: 454  YNRTVIPAPPQNLRFLRGTNALLTCGFYTDPRLPPAQVVWRRDGHKLMGSETANKYSV-F 512

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
            +  +L +  ++  D+  Y   + +   H     ++T++D+P PP   ++ E+   ++ + 
Sbjct: 513  EDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMGSITVVDRPDPPKYLSLAEVTDHNLTLN 572

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTE-----WISVKNITKTQTSIQ-NLKTNSSYRFRAY 1454
            W  P +  NS +I ++VE++E   TE     W  +K +      +Q +L+   +YRFR  
Sbjct: 573  WT-PGSAHNSPMIDFIVEFREEQHTEGKKWKWEEMKKVPADVQHVQLSLRPFCTYRFRVI 631

Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPT 1483
            AVNEV  SD SE ++ Y+       ++PT
Sbjct: 632  AVNEVGRSDPSEPSDTYRTSPAVPDRNPT 660



 Score = 79.8 bits (188), Expect = 8e-13
 Identities = 68/299 (22%), Positives = 134/299 (44%), Gaps = 21/299 (7%)

Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658
            +PP +V+W ++G+KL   +  N  +  +   +++  ++ + S++Y+ E  +         
Sbjct: 486  LPPAQVVWRRDGHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMG 545

Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKP------PLDDGGLELTKYAIEKH-EPDNN 1711
            ++ V D+P  P+  + + E++  ++T+ W P      P+ D    + ++  E+H E    
Sbjct: 546  SITVVDRPDPPK-YLSLAEVTDHNLTLNWTPGSAHNSPMID---FIVEFREEQHTEGKKW 601

Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771
            +W ++  V  DV+ +    L   C Y FRVIA N VG S+  E      +T+  VP    
Sbjct: 602  KWEEMKKVPADVQ-HVQLSLRPFCTYRFRVIAVNEVGRSDPSEPSD-TYRTSPAVPDRNP 659

Query: 1772 XXXXXXXIDNESVYITWFPSEK---NGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQ 1827
                    D +S+ ITW   +K   NG   + +    E ++   +W            +Q
Sbjct: 660  TGVRSESADPDSLVITWDEMDKMYHNGHGFLYEVSWREARKRDARWNSAEVKSPPFL-VQ 718

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
                 T ++ ++ A N +G+  P    +    G+    P++P   V +   + +VT+KW
Sbjct: 719  NTGTYTPFEIKVKAVNSLGSG-PAPEPEIGHSGE--DKPAEPPTGVKTTVINSTVTVKW 774



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 107/491 (21%), Positives = 181/491 (36%), Gaps = 58/491 (11%)

Query: 640  PKAQYVD----EGSDILLECRLVAIPEPDIA-WLFK-GEEIVPDENISVAIESDMHMYCS 693
            PK Q V     EG  I+L C       P +  W+ K    I   E + V ++  ++ + +
Sbjct: 97   PKQQQVHKESYEGESIILSCNPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLY-FSN 155

Query: 694  VLKITNVKKFQEGTYTVVA--VNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQ 748
            +L+  +   +      + A  +  E   SL +V      +   P   +   P  S++  +
Sbjct: 156  LLRNDSRTDYMCNAQYLAARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALR 215

Query: 749  GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKA 807
            G  V L     G P P + W K  K  +   T    D H+     +   + D+G Y  KA
Sbjct: 216  GHKVTLECIPKGLPTPKVEWKK--KDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKA 273

Query: 808  ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867
             NS G    S  +TVE         P ++ +          T++L  +    P PSITW 
Sbjct: 274  WNSHGFTTHSFTVTVEAA-------PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWS 326

Query: 868  RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927
             N   I+  E   +      + L++ +V    D+  Y+C A+N  G +     + +    
Sbjct: 327  INGRNITEVEEEPRRSVSGGV-LILRDV-VFADTAVYQCEATNKHGSALLNTFLHVVELP 384

Query: 928  VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987
               +      Y   EG+ ++++C+   +           IS +DH               
Sbjct: 385  PQILTSDGLLYRVTEGRNILMDCEVFGSPRPHITCGTLVISEVDH--------------- 429

Query: 988  XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI--RKLQDFEVKEKDVAILEVEINSE-- 1043
                 D GV  C VK     ++    E     +     Q+        A+L     ++  
Sbjct: 430  ----DDAGVYSCSVKHNNNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYTDPR 485

Query: 1044 --TADVVWERDGEIIKPKK--NKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDES 1095
               A VVW RDG  +   +  NKY   + G ++   + N   +D  +YSC    +L    
Sbjct: 486  LPPAQVVWRRDGHKLMGSETANKYSVFEDGTLK---VSNIQFNDSAQYSCEVISLLDHVK 542

Query: 1096 CTAEVTVVELP 1106
                +TVV+ P
Sbjct: 543  AMGSITVVDRP 553



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 4/181 (2%)

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545
            P  ++       + L CI  G+P PKV W  +DG+  +T+    ++              
Sbjct: 207  PHSSVLALRGHKVTLECIPKGLPTPKVEWKKKDGRLGETSGQLDKHNRWFHFESIGLNDD 266

Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605
              Y+C A+N HG    S  V ++  P      +   Q +  G+   +    EGIP P + 
Sbjct: 267  GEYECKAWNSHGFTTHSFTVTVEAAPYWV--KKPASQLYSPGETVRLDCQAEGIPTPSIT 324

Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665
            W  NG  +  + E          V+ ++++  + ++ Y  EA+N  G++ +   L V + 
Sbjct: 325  WSINGRNI-TEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVEL 383

Query: 1666 P 1666
            P
Sbjct: 384  P 384



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 107/542 (19%), Positives = 207/542 (38%), Gaps = 65/542 (11%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX---XXXXXX 1540
            V+KP   + + P E + L C   G+P P +TW  +G+ +   +                 
Sbjct: 295  VKKPASQLYS-PGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILRDV 353

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y+C A N HG    +  + + + P   ++++ +  +   G   L+   + G P
Sbjct: 354  VFADTAVYQCEATNKHGSALLNTFLHVVELPPQILTSDGLLYRVTEGRNILMDCEVFGSP 413

Query: 1601 PPEVIWYKNG-NKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASN---TAGTS 1654
             P +       +++++D    Y+ + K   +V     L+  + +       N     GT+
Sbjct: 414  RPHITCGTLVISEVDHDDAGVYSCSVKHNNNVSINAHLEVYNRTVIPAPPQNLRFLRGTN 473

Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            ++ +T   Y  P  P   V+ R                DG   +      K+    +  +
Sbjct: 474  AL-LTCGFYTDPRLPPAQVVWRR---------------DGHKLMGSETANKYSVFEDGTL 517

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774
            KV+++          + N++ +Y   VI+   +   +A+ S  +V +   D P       
Sbjct: 518  KVSNI----------QFNDSAQYSCEVISL--LDHVKAMGSITVVDRP--DPPK----YL 559

Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ----EGKKWKXXXXXXXXXARIQKLS 1830
                + + ++ + W P   +  SP+ID+ VE ++    EGKKWK         A +Q + 
Sbjct: 560  SLAEVTDHNLTLNWTPGSAH-NSPMIDFIVEFREEQHTEGKKWK-WEEMKKVPADVQHVQ 617

Query: 1831 IN----TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886
            ++     TY+FR+ A NE+G S P    D       + P   P       +   S+ + W
Sbjct: 618  LSLRPFCTYRFRVIAVNEVGRSDPSEPSDTYRTSPAV-PDRNPTGVRSESADPDSLVITW 676

Query: 1887 TEPES---NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943
             E +    NG   +  Y + ++  + K   +  +         ++N         ++ A 
Sbjct: 677  DEMDKMYHNGHGFL--YEVSWREAR-KRDARWNSAEVKSPPFLVQNTGTYTPFEIKVKAV 733

Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003
            N++G S P     +          PPT  ++  ++ S + +  W   + D    LLGY I
Sbjct: 734  NSLG-SGPAPEPEIGHSGEDKPAEPPTG-VKTTVINSTVTV-KWDAAQ-DVRGLLLGYKI 789

Query: 2004 AI 2005
             I
Sbjct: 790  HI 791



 Score = 58.0 bits (134), Expect = 3e-06
 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 9/135 (6%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693
           P + KKP +Q    G  + L+C+   IP P I W   G  I   E      E    +   
Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEE-----EPRRSVSGG 346

Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESV 752
           VL + +V       Y   A N+ G A L   L +    + PPQ++     +  V +G ++
Sbjct: 347 VLILRDVVFADTAVYQCEATNKHGSALLNTFLHV---VELPPQILTSDGLLYRVTEGRNI 403

Query: 753 ILSAQVVGNPRPTIT 767
           ++  +V G+PRP IT
Sbjct: 404 LMDCEVFGSPRPHIT 418



 Score = 47.6 bits (108), Expect = 0.004
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568
           AP +V+K   +    G TV+ +CQ EG P P ITW      I   ++         V  L
Sbjct: 291 APYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGV--L 348

Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603
           ++R+V   D   + C A N  G A   T L +VE P
Sbjct: 349 ILRDVVFADTAVYQCEATNKHGSALLNTFLHVVELP 384



 Score = 41.5 bits (93), Expect = 0.25
 Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 3/128 (2%)

Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539
            Q P + +  ++IT     DI L C   G P P   W +DG  +++    +          
Sbjct: 4    QPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRS--GLHLGTLKAEEEE 61

Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598
                    Y+C A ND+G   T  V V ++ +PV+    +  K+ ++     L     E 
Sbjct: 62   PLQQFEGHYRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSCNPPES 121

Query: 1599 IPPPEVIW 1606
              PP + W
Sbjct: 122  STPPVIHW 129



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 31/126 (24%), Positives = 50/126 (39%), Gaps = 6/126 (4%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728
            P   + ++  S  SV + W PP +  G+ L      K E  N+  +     D  V  + +
Sbjct: 875  PPASLRLQSPSETSVILYWAPPTEANGILLGYVIQHKQEGANSESLLQMISDPSVTHFEL 934

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
              L+ N  Y+F+VIA    G     E  PI ++ A  +                S  ++W
Sbjct: 935  HHLDPNSYYIFKVIAYTAAG-----EGPPIQLRGATMLEGVPPSNVTIVT-GTTSFNLSW 988

Query: 1789 FPSEKN 1794
             P E+N
Sbjct: 989  VPEERN 994



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 12/105 (11%)

Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-----MWMEVGKV- 2019
            P PP   L +  V  + +  +W TP     +P++ + +  R+   T      W E+ KV 
Sbjct: 553  PDPPKY-LSLAEVTDHNLTLNW-TPGSAHNSPMIDFIVEFREEQHTEGKKWKWEEMKKVP 610

Query: 2020 -DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063
             DV  ++ ++R      TY  R+ A NE+G S+P E  + ++  P
Sbjct: 611  ADVQHVQLSLRPFC---TYRFRVIAVNEVGRSDPSEPSDTYRTSP 652


>UniRef50_Q05D81 Cluster: MYLK protein; n=14; Eutheria|Rep: MYLK
           protein - Homo sapiens (Human)
          Length = 236

 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 41/116 (35%), Positives = 66/116 (56%)

Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545
           +KL  +       E    E+  + P F + +R     +GS  +F+C++EGYP P++ WF+
Sbjct: 97  EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 156

Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601
               I+ S+ FQ+ YD+D   +L+I +V  +D   +TC A N+ G A+ T ELIVE
Sbjct: 157 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           + P FSK  +   V EGS    +C++   P+P++ W FK ++ +  E+    I+ D    
Sbjct: 119 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 176

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732
           CS++ I++V    +  YT  AVN  GEA+    L ++T E+
Sbjct: 177 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 216



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 5/122 (4%)

Query: 805 LKAENSEGIAETSAVITVEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
           L AE  E  +E  +   +E   EE     P F    +++ V E    +   ++   P P 
Sbjct: 94  LNAEKLE--SEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE 151

Query: 864 ITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922
           + W+++++ I  S     ++D + N  L+I++V  + D   Y C A NS G+++  A + 
Sbjct: 152 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELI 210

Query: 923 ID 924
           ++
Sbjct: 211 VE 212



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164
            P     +++ +V +G+ A F+ ++    D  V WFKD   I+ S H Q+  D      L 
Sbjct: 121  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180

Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192
            I D   DD  +Y+C+    +G + CTA L VE
Sbjct: 181  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTS 1654
            IEG P PEV+W+K+   +   + + I   E  +  + I ++     +KYT +A N+ G +
Sbjct: 144  IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 203

Query: 1655 SVEVTLKV 1662
            +    L V
Sbjct: 204  TCTAELIV 211



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%)

Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791
           P   + ++ + V +G +     ++ G P P + W K+++ ++         D D +   I
Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180

Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
           +      D+  YT KA NS G A  +A + VE   E   E
Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 220


>UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74;
           Coelomata|Rep: Roundabout homolog 1 precursor - Homo
           sapiens (Human)
          Length = 1651

 Score = 90.2 bits (214), Expect = 5e-16
 Identities = 78/327 (23%), Positives = 132/327 (40%), Gaps = 25/327 (7%)

Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664
           SD G  + V            A++     P+F K+P    V        +C     P P 
Sbjct: 233 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 292

Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724
           + W  K +  +P     +    D H     LKI  V     G+YT VA N  G+A     
Sbjct: 293 VRWR-KDDGELPKSRYEI---RDDH----TLKIRKVTAGDMGSYTCVAENMVGKAEASAT 344

Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN--------KPVK 776
           L +    +EPP  +   +  +V  G +V    +  GNP+P I W +          +P +
Sbjct: 345 LTV----QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQ 400

Query: 777 ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836
           +    S   T  +TI   ++  D G Y  +  N  G   T A + V +   +   PP+  
Sbjct: 401 SSSRFSVSQTGDLTITNVQR-SDVGYYICQTLNVAGSIITKAYLEVTDVIADR-PPPVIR 458

Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896
                 TV   GT  L    T +PVP+I W ++  ++S  ++  +  +   +++    + 
Sbjct: 459 QGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLG 518

Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTI 923
              D+G Y C+AS  +G+++  A + +
Sbjct: 519 ---DTGRYTCIASTPSGEATWSAYIEV 542



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 108/484 (22%), Positives = 179/484 (36%), Gaps = 44/484 (9%)

Query: 630  EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689
            E  PP   + P    V +G    L C+    P P I W   GE +  D++   +    + 
Sbjct: 64   EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123

Query: 690  M-YCSVLKITNVKKFQ--EGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMI 745
                  L+I + +K +  EG Y  VA N  GEA S    L++     +  Q   P   ++
Sbjct: 124  SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQ--NP-SDVM 180

Query: 746  VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
            V  GE  ++  Q   G+P PTI+W K+  P+     +       + I   +K  D G Y 
Sbjct: 181  VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK-SDAGKYV 239

Query: 805  LKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863
                N  G  E+  A +TV        E P F+ R   + V    + +       +PVP+
Sbjct: 240  CVGTNMVGERESEVAELTV-------LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 292

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
            + W +++  +  S    ++     I  V        D G Y CVA N  GK+   A +T+
Sbjct: 293  VRWRKDDGELPKSRYEIRDDHTLKIRKVTAG-----DMGSYTCVAENMVGKAEASATLTV 347

Query: 924  DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-------DHREII 976
                   VK   +      G+TV  +C+ +       +  ++    +             
Sbjct: 348  QEPPHFVVK--PRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 405

Query: 977  QEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKETI----PEFIRK--LQDF 1026
               +            DVG   C    +     T   L V + I    P  IR+  +   
Sbjct: 406  SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465

Query: 1027 EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086
               +    +  V   S    ++W +DG ++  + ++    + G    L IR   + D G 
Sbjct: 466  VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDTGR 522

Query: 1087 YSCI 1090
            Y+CI
Sbjct: 523  YTCI 526



 Score = 77.4 bits (182), Expect = 4e-12
 Identities = 108/462 (23%), Positives = 184/462 (39%), Gaps = 56/462 (12%)

Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEI--DS 1394
            I  +   L I     +DAG Y     N  G  + E+  +T+L++PS   +P+ L +  D 
Sbjct: 218  ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDD 277

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRA 1453
            S+   C    E  G+       V +++ D     S   I    T  I+ +       +  
Sbjct: 278  SAEFKC----EARGDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTC 330

Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTEPNEDIELTCIFGGVPQP 1511
             A N V  ++AS T           +Q P   V KP   +       +   C   G PQP
Sbjct: 331  VAENMVGKAEASATLT---------VQEPPHFVVKPRDQVVAL-GRTVTFQCEATGNPQP 380

Query: 1512 KVTWYRDGKK---------LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
             + W R+G +           +++ +                   Y C   N  G + T 
Sbjct: 381  AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK 440

Query: 1563 CVVG----IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618
              +     I  +P   I    + Q   V   ++++ V  G P P ++W K+G  L + ++
Sbjct: 441  AYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG-VLVSTQD 499

Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD-----KPSKPEGPV 1673
              I   E   V++I+  K   + +YT  AS  +G ++    ++V +     +P +P  P 
Sbjct: 500  SRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPN 558

Query: 1674 I---------MREISRESVTIEWKPPLDDGGLELTKYAIEK-HEPDNNRWIKVADVDRDV 1723
            +         + ++SR +VT+ W+P L+ G    T Y IE       + W  VA+ +   
Sbjct: 559  LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSSWQTVAE-NVKT 616

Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764
            ET  I+ L  N  Y+F V A N  G S+  + S+P+  +  L
Sbjct: 617  ETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL 658



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 98/408 (24%), Positives = 157/408 (38%), Gaps = 39/408 (9%)

Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYD 1064
            T + L  ++  P  +    D  V + + A L  +     T  + W + GE ++  K+   
Sbjct: 57   TGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 116

Query: 1065 FEKR----GHIRKLYIRN--TSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRL 1113
              +     G +  L I +   S  DEG Y C+ R+      S  A + V  L  +     
Sbjct: 117  SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP 176

Query: 1114 QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171
             +  V  G  A  E +  +G  +  + W KDGS +   +  ++TI G K  L I      
Sbjct: 177  SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGGK--LMITYTRKS 233

Query: 1172 DAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225
            DAG+Y C   N      S+   +  +E PS    ++ P  + V  +  A    E   + +
Sbjct: 234  DAGKYVCVGTNMVGERESEVAELTVLERPSF---VKRPSNLAVTVDDSAEFKCEARGDPV 290

Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284
                ++K        ++ +  D    TL IRK T  D   YTCV  +     +    + V
Sbjct: 291  PTVRWRKDDGELPKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347

Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--- 1341
            + PP  V   R+  +  G  VT   +    PQP   W           +  P   S+   
Sbjct: 348  QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV 407

Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCG----HADVEMNVTILDKPSP 1383
              +  LTI  V+ +D G Y  +  N  G     A +E+   I D+P P
Sbjct: 408  SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 455



 Score = 70.5 bits (165), Expect = 5e-10
 Identities = 71/274 (25%), Positives = 112/274 (40%), Gaps = 14/274 (5%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM-Y 691
           PP F  KP+ Q V  G  +  +C     P+P I W  +G + +          S   +  
Sbjct: 350 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEPLKSMIVRQG 749
              L ITNV++   G Y    +N  G       L++     ++ PP + +   +  V   
Sbjct: 410 TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 469

Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809
            + +LS    G+P PTI W K+   V    ++     + +  ++  K+ D G YT  A  
Sbjct: 470 GTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIAST 529

Query: 810 SEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868
             G A  SA I V+E       P P   N       K +     V  V+RN V +++W  
Sbjct: 530 PSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPE-----VTDVSRNTV-TLSWQP 583

Query: 869 N-NEIISPSETITQNF---DGENIELVITNVDSE 898
           N N   +P+  I + F    G + + V  NV +E
Sbjct: 584 NLNSGATPTSYIIEAFSHASGSSWQTVAENVKTE 617



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 122/538 (22%), Positives = 207/538 (38%), Gaps = 59/538 (10%)

Query: 731  EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--- 787
            E  PP+++E    +IV +GE   L+ +  G P PTI W K  + V+    K D  +H   
Sbjct: 64   EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET--DKDDPRSHRML 121

Query: 788  ----SITILK----PKKVKDEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINR 838
                S+  L+     K   DEGVY   A N  G A + +A + V    ++  + P  +  
Sbjct: 122  LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDV-- 179

Query: 839  FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898
               + V E   ++       +P P+I+W ++    SP +   +       +L+IT    +
Sbjct: 180  --MVAVGEPAVME-CQPPRGHPEPTISWKKDG---SPLDDKDERITIRGGKLMIT-YTRK 232

Query: 899  IDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQK-SYETEEGKTVILECQTSHTV 956
             D+G Y CV +N  G + S  A +T+ +E+ +FVK     +   ++      E +     
Sbjct: 233  SDAGKYVCVGTNMVGERESEVAELTV-LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVP 291

Query: 957  STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012
            + +W  +  E+      EI  +              D+G   C+ ++     E S  L V
Sbjct: 292  TVRWRKDDGELP-KSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGE-----IIKPKKNKYDFE 1066
            +E  P F+ K +D  V        + E        + W R+G        +P ++   F 
Sbjct: 348  QEP-PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFS 406

Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVT--VVELPPEIITR-LQNQK 1117
                   L I N    D G Y C   +           EVT  + + PP +I +   NQ 
Sbjct: 407  V-SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465

Query: 1118 VNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176
            V            T      + W KDG  +  S         +   L+I    L D G Y
Sbjct: 466  VAVDGTFVLSCVATGSPVPTILWRKDG--VLVSTQDSRIKQLENGVLQIRYAKLGDTGRY 523

Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTW 1229
            +C      G +  +A + V+E  +      P +  L+P+        ++   T+ ++W
Sbjct: 524  TCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSW 581



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 109/502 (21%), Positives = 192/502 (38%), Gaps = 58/502 (11%)

Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS-----NHIQLTID 1157
            + PP I+    +  V+KG  AT   +   +    + W+K G  ++       +H  L   
Sbjct: 65   DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124

Query: 1158 GKKQKLKIYDC--DLDDAGEYSCEVGNSKCTAI---LTVEEPSINFTLRL-PEFILVPAN 1211
            G    L+I        D G Y C   N    A+    ++E   +    R  P  ++V   
Sbjct: 125  GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVG 184

Query: 1212 TDAYLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269
              A +  + P    +  ++W K  S ++D ++   I   K   L+I    + D  +Y CV
Sbjct: 185  EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITYTRKSDAGKYVCV 241

Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF--------PQPNDEW 1321
                    + + EV E    +   ER   +KR S++ + VD  A         P P   W
Sbjct: 242  --GTNMVGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRW 295

Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381
              +   + K ++          +L I+KV   D G Y    EN  G A+    +T+ + P
Sbjct: 296  RKDDGELPKSRYEIRD----DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPP 351

Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGN-STIIYY--------VVEYQEIDTTEWISVKN 1432
                KP   ++ +    + + + E TGN    I++        +  YQ   ++   SV  
Sbjct: 352  HFVVKPRD-QVVALGRTVTF-QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409

Query: 1433 I-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLK 1489
                T T++Q  +++  Y    Y    ++++ +  T  Y +V      + P V  + P+ 
Sbjct: 410  TGDLTITNVQ--RSDVGY----YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV- 462

Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXX 1547
            N T   +    L+C+  G P P + W +DG  + T  +  +                   
Sbjct: 463  NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGR 522

Query: 1548 YKCIAFNDHGEVETSCVVGIQQ 1569
            Y CIA    GE   S  + +Q+
Sbjct: 523  YTCIASTPSGEATWSAYIEVQE 544



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 5/94 (5%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569
           P FV++          + +F+C+  G P P + W +    + P   +++   DD+  TL 
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIR--DDH--TLK 316

Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603
           IR+V   D G++TCVA+N  G A ++  L V+ P
Sbjct: 317 IRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 350



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 3/89 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVHE 1924
            PS P    V++ +  +VTL W +P  N G+  T+YIIE F    G SW + V        
Sbjct: 561  PSAPSKPEVTDVSRNTVTLSW-QPNLNSGATPTSYIIEAFSHASGSSW-QTVAENVKTET 618

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE 1953
              I+ +K     +F + A N  G+S P++
Sbjct: 619  SAIKGLKPNAIYLFLVRAANAYGISDPSQ 647



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 38/238 (15%)

Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-----IIKPSQDFQMYYDDDN 564
           P FV K R +    G TV F+C+  G P+P I W R+ +       +P Q     +    
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQS-SSRFSVSQ 409

Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624
              L I  V   D G + C   N AG       +I +A L     E+T            
Sbjct: 410 TGDLTITNVQRSDVGYYICQTLNVAG------SIITKAYL-----EVTDV---------- 448

Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684
              I +  PP   + P  Q V      +L C     P P I W   G  +   ++    +
Sbjct: 449 ---IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQL 505

Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEP 740
           E+       VL+I   K    G YT +A    GEA+    ++++      +PP+  +P
Sbjct: 506 EN------GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDP 557



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNT 2023
            +PS P+ P E+  V  N V  SW  P  + GA    Y I A    + + W  V + +V T
Sbjct: 560  IPSAPSKP-EVTDVSRNTVTLSW-QPNLNSGATPTSYIIEAFSHASGSSWQTVAE-NVKT 616

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
                I+ L  N  Y+  + A N  G+S+P +  +P K
Sbjct: 617  ETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVK 653



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 40/174 (22%), Positives = 64/174 (36%), Gaps = 13/174 (7%)

Query: 1507 GVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564
            G P+P ++W +DG  L  K  + T                   Y C+  N  GE E+   
Sbjct: 196  GHPEPTISWKKDGSPLDDKDERITIRG-GKLMITYTRKSDAGKYVCVGTNMVGERESEVA 254

Query: 1565 -VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623
             + + ++P       ++     V D         G P P V W K+  +L   + Y I  
Sbjct: 255  ELTVLERPSFVKRPSNLAV--TVDDSAEFKCEARGDPVPTVRWRKDDGELPKSR-YEI-- 309

Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVI 1674
                  ++I+++       YT  A N  G +    TL V + P    KP   V+
Sbjct: 310  -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVV 362


>UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14681, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1751

 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 91/362 (25%), Positives = 150/362 (41%), Gaps = 24/362 (6%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T V  G P P V W      L  + +  I      +V+ + ++++S  + YT  A +T 
Sbjct: 25   ITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR----NVLELTDVRQS--ANYTCVAMSTL 78

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G       + V   P  P  PV+  E +  S+T+ W    D G  E   Y I +H+   +
Sbjct: 79   GVIEAMAQITVKALPKAPGTPVVT-ERTATSITLTW----DSGNPEPVSYYIIQHKSKYS 133

Query: 1712 RWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
              +   ++D    T Y +  L+   +Y FRV+A N +G      SE I  KTA   PS  
Sbjct: 134  DDL-YKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIG--RGPPSEIIEAKTAEQAPSTA 190

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827
                    + + +  I W   E+  G  +   + Y ++  Q    W+           IQ
Sbjct: 191  PRQVRGHMMSSTTAVIHWDEPEEANGQIMGYRVYYTMDSSQHVNLWEKQIVRGSKFVTIQ 250

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
             L  N TY  ++ A   +G   P + D +I I KT  P SQP +F     +  S+ L W 
Sbjct: 251  GLIPNKTYYIKVLAYTSVGDG-PLSPDLQI-ITKTGVP-SQPTDFKAEAKSETSILLSWI 307

Query: 1888 EPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946
             P   G  + IT Y + ++        +I     +   + ++++K      FR++A +  
Sbjct: 308  APAQTGQENQITGYELVYRKSDDTEEKRISFEPTTT--YLLKDLKPFTTYTFRLAARSKH 365

Query: 1947 GV 1948
            GV
Sbjct: 366  GV 367



 Score = 60.9 bits (141), Expect = 4e-07
 Identities = 66/289 (22%), Positives = 116/289 (40%), Gaps = 20/289 (6%)

Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677
            EY+ +T+ +   + I +L+   +   T+ A  T G  +      +    + PE P +M  
Sbjct: 502  EYDDSTEHE---MIITDLQAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVS 558

Query: 1678 ISRESVTI-EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736
             +     + +W PP    G  L  Y +     D +    +   +R+   Y  +++++   
Sbjct: 559  TTNMGTALLQWHPPAITHG-PLQGYRLRFGRKDMDPLTVIEFPERE-NHYTTKEIHKGAS 616

Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEK 1793
            Y FR+ A+N VGF E    E   + T  DVPS              ++ ++W P   +E+
Sbjct: 617  YTFRLSARNKVGFGEETVKE---VSTNEDVPSGYPQSITAEGATTSTIQVSWQPVLLTER 673

Query: 1794 NGGSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850
            NG   II Y +   +I       +           +  L  +TTY  ++ A    G+  P
Sbjct: 674  NG--KIIKYALQYKDINSPRSPSELFITAPESTVILDGLKADTTYDIKMCAFTSKGSG-P 730

Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES-NGGSPIT 1898
            Y+   +    + L      +NF V  +   SV L W  P++ N   P T
Sbjct: 731  YSPSVQFRT-QPLDQAVFAKNFHVKAAMKSSVLLTWEIPDTYNPAQPFT 778



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 12/185 (6%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+      +  I  G  V +       P P  +W++ ++ +       P  D       
Sbjct: 5    PPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNV 58

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            ++  +   +  Y     +  G  +    +T+   P  PG P + E  ++SI + WD    
Sbjct: 59   LELTDVRQSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTWD---- 114

Query: 1407 TGN-STIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
            +GN   + YY+++++   + + +  +  +  T+ S+  L   S Y FR  A+N +     
Sbjct: 115  SGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPP 174

Query: 1465 SETTE 1469
            SE  E
Sbjct: 175  SEIIE 179



 Score = 50.0 bits (114), Expect = 7e-04
 Identities = 62/274 (22%), Positives = 106/274 (38%), Gaps = 21/274 (7%)

Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRIY 1840
            S+ +TW   +     P+  Y ++ K +     +K           +  LS  + Y+FR+ 
Sbjct: 108  SITLTW---DSGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVV 164

Query: 1841 ARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899
            A N IG   P    +  T  +   T P Q R  ++S +T+    + W EPE   G  I  
Sbjct: 165  AINNIGRGPPSEIIEAKTAEQAPSTAPRQVRGHMMSSTTA---VIHWDEPEEANGQ-IMG 220

Query: 1900 YIIEFKTVKGKS---WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956
            Y + +     +    W K +  G       I+ +        ++ A  +VG   P  S  
Sbjct: 221  YRVYYTMDSSQHVNLWEKQIVRGSKFVT--IQGLIPNKTYYIKVLAYTSVGDG-PL-SPD 276

Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA-PLLGYNIAIRDVTKTMWME 2015
            +++     VPS PT   +        ++ SW  P   G    + GY +  R    T    
Sbjct: 277  LQIITKTGVPSQPT-DFKAEAKSETSILLSWIAPAQTGQENQITGYELVYRKSDDTEEKR 335

Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049
            +      T  + ++DL    TY  R+ AR++ G+
Sbjct: 336  ISFEPTTT--YLLKDLKPFTTYTFRLAARSKHGV 367



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 20/135 (14%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           +PP FS  P    +  G  + + C  V  P P + W+   E++ P        E DM + 
Sbjct: 4   VPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIG 55

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749
            +VL++T+V+  Q   YT VA++  G       + +K   K P  P V E   + I    
Sbjct: 56  RNVLELTDVR--QSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTW 113

Query: 750 ESVILSAQVVGNPRP 764
           +S        GNP P
Sbjct: 114 DS--------GNPEP 120



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 73/360 (20%), Positives = 132/360 (36%), Gaps = 20/360 (5%)

Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN 1554
            P   + +TC+  G P P V W    + L         R               Y C+A +
Sbjct: 19   PGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR--NVLELTDVRQSANYTCVAMS 76

Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
              G +E    + ++  P        + ++        +T   +   P  V +Y   +K +
Sbjct: 77   TLGVIEAMAQITVKALPKAP-GTPVVTERTATS----ITLTWDSGNPEPVSYYIIQHKSK 131

Query: 1615 -NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-PSKPE 1670
             +D  Y       T+   +  L      ++ + A N  G    S  +  K  ++ PS   
Sbjct: 132  YSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPPSEIIEAKTAEQAPSTAP 191

Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCI 1728
              V    +S  +  I W  P +  G ++  Y +  +  D+++ + +    + R  +   I
Sbjct: 192  RQVRGHMMSSTTAVIHWDEPEEANG-QIMGYRV-YYTMDSSQHVNLWEKQIVRGSKFVTI 249

Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788
            Q L  N  Y  +V+A   VG         I+ KT   VPS           +  S+ ++W
Sbjct: 250  QGLIPNKTYYIKVLAYTSVGDGPLSPDLQIITKTG--VPSQPTDFKAEAKSET-SILLSW 306

Query: 1789 F-PSEKNGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846
              P++    + I  Y+ V  K +  + K           ++ L   TTY FR+ AR++ G
Sbjct: 307  IAPAQTGQENQITGYELVYRKSDDTEEKRISFEPTTTYLLKDLKPFTTYTFRLAARSKHG 366



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982
            H++ +EN+ +  E    ++A   VG    +  Q VR E+   VPS P   +E+  + S+ 
Sbjct: 396  HQYLLENLDKFTEYRVSVTAHTDVGAGPESPPQLVRTEED--VPSGPPRKVEVEALNSSS 453

Query: 1983 VMTSWGTP 1990
            +   W +P
Sbjct: 454  IKVIWRSP 461


>UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9
            SCAF14729, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1238

 Score = 89.8 bits (213), Expect = 7e-16
 Identities = 101/434 (23%), Positives = 175/434 (40%), Gaps = 35/434 (8%)

Query: 628  ILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685
            ++E  P   S K  +    V  G ++LLEC    +P P I W   GE++V    +     
Sbjct: 240  VVESAPTWLSPKGSSSSTLVLLGEELLLECIAAGVPTPHITWRKDGEDLVVRSPVKA--- 296

Query: 686  SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745
                 +  +++I        G Y   A N+       I +++K      P  +E    ++
Sbjct: 297  ---KNFNKMIQIPRASFEDAGEYVCTATNKLDYIQHTITVQVKAA----PFWLEKPADLV 349

Query: 746  VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYT 804
            +   E   L  +  G PRPT+TW  N +P+     + + +    T +L+     +  VY 
Sbjct: 350  LAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQ 409

Query: 805  LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864
              A N  G    +A + V      +A P +  +R + + V E     L  R   +PVP +
Sbjct: 410  CNASNPYGYLLANAFVNV-----LHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPEL 464

Query: 865  TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924
             W +  +          + +G    L I N+   +D G Y CV SN AG+  +  +V I+
Sbjct: 465  RWSKYGQGSLEGNRFRTHSNG---TLEIKNI-QVVDQGAYLCVVSNVAGRDEN--QVRIE 518

Query: 925  VEKVTFVKHLQKSYETEEGKTVILEC--QTSHT--VSTKWYHNKKEISGMDHREIIQEGR 980
            V++ T +       +   G  V  EC  +T  T  V+T W    K ++ +  R  + E  
Sbjct: 519  VKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPVT-LGWRISMDESN 577

Query: 981  XXXXXXXXXXXXDVGVIKCIVK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037
                        D G   C+VK   +Q++++  ++    P+    L+  +  E+ V +  
Sbjct: 578  ---LVISNINTADGGNYTCLVKSELEQKSASARLMVMDRPDPPTDLELSDPHERSVRLSW 634

Query: 1038 VEINSETADVVWER 1051
            V  NS    +  ER
Sbjct: 635  VPGNSHHNPITGER 648



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 7/206 (3%)

Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE-NRXXXXXXXX 1540
            +EKP  ++   P ED  L C   G P+P VTW+ +G+ +   T +   E +         
Sbjct: 342  LEKPA-DLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTV 400

Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600
                   Y+C A N +G +  +  V +       + + +   K   G    +     G P
Sbjct: 401  TTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSP 460

Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660
             PE+ W K G   +   E N         + IK ++      Y    SN AG    +V +
Sbjct: 461  VPELRWSKYG---QGSLEGNRFRTHSNGTLEIKNIQVVDQGAYLCVVSNVAGRDENQVRI 517

Query: 1661 KVYDKPSKPEGPVIMREISRESVTIE 1686
            +V +       P  M+ I    V  E
Sbjct: 518  EVKEPTLIVTRPTDMKVIRGADVRFE 543



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 9/160 (5%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553
            E++ L CI  GVP P +TW +DG+ L      KA   N+               Y C A 
Sbjct: 263  EELLLECIAAGVPTPHITWRKDGEDLVVRSPVKAKNFNK-MIQIPRASFEDAGEYVCTAT 321

Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613
            N    ++ +  V ++  P       D+    +  ++  +    +G P P V W+ NG  +
Sbjct: 322  NKLDYIQHTITVQVKAAPFWLEKPADLVLAPE--EDGRLVCRSDGAPRPTVTWFINGEPI 379

Query: 1614 E-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652
            + +  + N+    +T V+R   +   +++ Y   ASN  G
Sbjct: 380  DPSTLQPNVEVSGETVVLR--TVTTLNNAVYQCNASNPYG 417



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 55/262 (20%), Positives = 98/262 (37%), Gaps = 12/262 (4%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEP 1194
            + W KDG ++   + ++     K   ++I     +DAGEY C   N        +TV+  
Sbjct: 279  ITWRKDGEDLVVRSPVKAKNFNKM--IQIPRASFEDAGEYVCTATNKLDYIQHTITVQVK 336

Query: 1195 SINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253
            +  F L  P + +L P      +          VTW+     I D        +V   T+
Sbjct: 337  AAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPI-DPSTLQPNVEVSGETV 395

Query: 1254 IIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVD 1310
            ++R  T  +   Y C   +          V V+   P+I+    EY ++  GS   L   
Sbjct: 396  VLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCR 455

Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370
            Y   P P   W   SK  +            + +L IK ++  D G Y   + N  G  +
Sbjct: 456  YFGSPVPELRW---SKYGQGSLEGNRFRTHSNGTLEIKNIQVVDQGAYLCVVSNVAGRDE 512

Query: 1371 VEMNVTILDKPSPPGKPNILEI 1392
             ++ + + +      +P  +++
Sbjct: 513  NQVRIEVKEPTLIVTRPTDMKV 534



 Score = 48.0 bits (109), Expect = 0.003
 Identities = 75/384 (19%), Positives = 147/384 (38%), Gaps = 30/384 (7%)

Query: 1044 TADVVWERDGE--IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101
            T  + W +DGE  +++      +F K      + I   S  D GEY C   ++    + T
Sbjct: 276  TPHITWRKDGEDLVVRSPVKAKNFNKM-----IQIPRASFEDAGEYVCTATNKLDYIQHT 330

Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157
            +   V+  P  + +  +  +                   V WF +G  I  S  +Q  ++
Sbjct: 331  ITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPST-LQPNVE 389

Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL----PEFILVPANTD 1213
               + + +      +   Y C   N     +       ++ T R+     E++ V   + 
Sbjct: 390  VSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSR 449

Query: 1214 AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272
            A+L        + ++ W K      +  +F   S+    TL I+     DQ  Y CV+ +
Sbjct: 450  AFLDCRYFGSPVPELRWSKYGQGSLEGNRFRTHSN---GTLEIKNIQVVDQGAYLCVVSN 506

Query: 1273 A--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKII 1328
               +   ++++EV E P  IV    + ++ RG+DV     V   A       W+  +K +
Sbjct: 507  VAGRDENQVRIEVKE-PTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPV 565

Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388
                  + S+D   ++L I  +   D G Y   +++          + ++D+P PP    
Sbjct: 566  TL--GWRISMDE--SNLVISNINTADGGNYTCLVKSELEQKSASARLMVMDRPDPPTDLE 621

Query: 1389 ILEIDSSSINICWDEPENTGNSTI 1412
            + +    S+ + W  P N+ ++ I
Sbjct: 622  LSDPHERSVRLSW-VPGNSHHNPI 644



 Score = 44.0 bits (99), Expect = 0.046
 Identities = 47/202 (23%), Positives = 81/202 (40%), Gaps = 16/202 (7%)

Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686
           ++L   P     + +   V EGS   L+CR    P P++ W   G+  +  E       S
Sbjct: 426 NVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSL--EGNRFRTHS 483

Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746
           +       L+I N++   +G Y  V  N  G     + +++    KEP  ++     M V
Sbjct: 484 N-----GTLEIKNIQVVDQGAYLCVVSNVAGRDENQVRIEV----KEPTLIVTRPTDMKV 534

Query: 747 RQGESVILSAQVVGNPRP--TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804
            +G  V     V  +     T TW K  KPV  L  +   D  ++ ++      D G YT
Sbjct: 535 IRGADVRFECAVKTDATTPVTTTWMKGTKPV-TLGWRISMDESNL-VISNINTADGGNYT 592

Query: 805 -LKAENSEGIAETSAVITVEEP 825
            L     E  + ++ ++ ++ P
Sbjct: 593 CLVKSELEQKSASARLMVMDRP 614



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 12/141 (8%)

Query: 633 PPTFSKKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           PPT  K+   +++ +  D +++EC     P P  +W   G       N++   ++ M  +
Sbjct: 2   PPTIIKQSMKEHIVDAKDAMVIECEAKGNPHPIFSWRRNGRYY----NVARDPQASMRRH 57

Query: 692 CSVLKI--TNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
              L I   N  +  E  Y  VA N  G A S  I L++      P ++IEP   +++  
Sbjct: 58  SGTLDIYARNNPEQYEAEYQCVASNMYGSAYSNKIRLRLYRAPVWPREIIEP---VVISA 114

Query: 749 GESVILSAQ-VVGNPRPTITW 768
           G  ++LS     G P+P   W
Sbjct: 115 GLPLVLSCDPPPGPPKPETYW 135



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 15/196 (7%)

Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP--E 1890
            T Y+FR+ A NEIG S P     +        P   P+N     +   ++ + W EP   
Sbjct: 707  TYYEFRVIAINEIGMSRPSRPSSRFQ-SSGAPPDVIPKNLKGVGTWRNNMEISW-EPLAY 764

Query: 1891 SNGGSPITNYIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV- 1948
             +   P   Y++ +K    +  W    T     + +  +     D    ++ A N  G+ 
Sbjct: 765  KDWNGPHLKYLVWWKRKDSREEWKNATTRWSKYYIYGADTFTPYD---LKVQAVNDFGMG 821

Query: 1949 --SLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDG-GAPLLGYNI 2003
              S      S      A  P P TAPL +R+  + SN V   W     D     L  Y +
Sbjct: 822  PESPIVTGFSGEDLSDAFSPGPLTAPLNLRVSDIESNQVTVHWDPVSHDSIMGELKEYKV 881

Query: 2004 AI-RDVTKTMWMEVGK 2018
               RD ++  W+ V +
Sbjct: 882  YYWRDSSQLRWLRVNR 897



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552
           +KL   +   + +   AP ++EK            +  C+ +G PRP +TWF     I P
Sbjct: 322 NKLDYIQHTITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDP 381

Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591
           S   Q   +     T+V+R V   +   + C A N  G+
Sbjct: 382 S-TLQPNVEVSG-ETVVLRTVTTLNNAVYQCNASNPYGY 418


>UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin,
            partial; n=6; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to hemicentin, partial -
            Strongylocentrotus purpuratus
          Length = 1839

 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 79/334 (23%), Positives = 132/334 (39%), Gaps = 28/334 (8%)

Query: 597  ELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655
            EL++ A   SD G+   V               +E  P  F   P  +    G  + +EC
Sbjct: 1316 ELVISAVENSDEGTYTCVASNSGGDDEFSTVVTVESAP-YFPYPPSDESKRPGESVDIEC 1374

Query: 656  RLVAIPEPDIAWLFKGE-----EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
            R   +P P + W   G+     E   D      +  D  +  + + ITN++      +  
Sbjct: 1375 RSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGDPQL--ATISITNLQTTDSNVFQC 1432

Query: 711  VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG---------- 760
            +A N   E    +VL + +     P      + + V Q +S   +  V G          
Sbjct: 1433 IATNMYKEELTSVVLNVFSIPASIPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISV 1492

Query: 761  -NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819
             +P P ITW +  + +++    S  +     ++   ++ DEG YT  A N+ G  E S V
Sbjct: 1493 LDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVASNTGGDDEFSTV 1552

Query: 820  ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879
            +TVE        PP  + + + I   E+  + L  R T  P P+  W ++  + +     
Sbjct: 1553 VTVEYDV-----PPSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSND 1607

Query: 880  TQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
              + DG N  LVI ++ +  D G Y+C A N  G
Sbjct: 1608 RVSLDGGN--LVIESL-TTADDGQYQCFAKNRLG 1638



 Score = 81.0 bits (191), Expect = 3e-13
 Identities = 122/558 (21%), Positives = 209/558 (37%), Gaps = 67/558 (12%)

Query: 628  ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687
            +L+  PP+  ++P++   D+   + L CR +  PEP   W   G     D N   +++  
Sbjct: 509  LLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG- 567

Query: 688  MHMYCSVLKITNVKKFQEGTYTVVAVNR----EGEASLPIVLKIKTGEKEPPQVIEPLKS 743
                   L I ++    +G Y   A NR    + E + P ++++  G        +PLK 
Sbjct: 568  -----GNLVIESLTTADDGQYQCFANNRLVMEQFENTAPAMVQLSQG--------QPLK- 613

Query: 744  MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKD-E 800
              +R G S  +     GNP P I W   +    ++    + + D     +       D +
Sbjct: 614  --LRCGGSPGIPN---GNPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAK 668

Query: 801  GVYTLKAENSEGIAETS--AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858
            G Y L   N  G+ + S   +++V +     +   L  +           + KL      
Sbjct: 669  GYYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFG 728

Query: 859  NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918
             P P ITW R  E +     ++    G+   LVI+ V++  D G Y CVASN+ G     
Sbjct: 729  YPTPVITWKRGEEQLQSGGRVSIEESGQ--ALVISAVENS-DEGTYTCVASNTGGDDEFS 785

Query: 919  ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKE----ISGMDH 972
              VT  VE   +            G++V +EC++      + +W  N +      S +D 
Sbjct: 786  TVVT--VESAPYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDT 843

Query: 973  RE---IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVK 1029
                 +  + +            D  V +CI  ++    +  V   +  F  ++  F   
Sbjct: 844  ERWTVVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPL 903

Query: 1030 EKDVAILEVEI--------NSETADVVWERDGEIIKPKKNKYDF-EKRGHIRKLYIRNTS 1080
             + ++++E +               + W   G ++     KY   E  G    L I N  
Sbjct: 904  TRRLSVVEDDSAKFICHSRGRPDPTITWTFKGSVL-TNGIKYTINETEG---SLVINNVK 959

Query: 1081 VHDEGEYSCIL------RDESCTAEVTVVEL-PPEIITRLQNQKVNKGNKATFEIELTKG 1133
              D GEY C         D   T   T+  L    I     N  + +GN ATF+ E+T  
Sbjct: 960  KVDGGEYECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYD 1019

Query: 1134 DALVR----WFKDGSEIQ 1147
            + L+     W KDG  ++
Sbjct: 1020 EELIEPYVYWMKDGQRLE 1037



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 83/324 (25%), Positives = 127/324 (39%), Gaps = 38/324 (11%)

Query: 661  PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720
            P P I W    E++     +S+      H +   L I+ V+   EGTYT VA N  G+  
Sbjct: 1291 PTPVITWKRGEEQLQSGGRVSI------HEH--ELVISAVENSDEGTYTCVASNSGGDDE 1342

Query: 721  LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780
               V+ +++     P    P      R GESV +  +  G P PT+ W  N +P     +
Sbjct: 1343 FSTVVTVESA----PYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFES 1398

Query: 781  KSD--------GDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831
              D        GD    TI +   +  D  V+   A N      TS V+ V       A 
Sbjct: 1399 NRDTERWEVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIP---AS 1455

Query: 832  PPLFINRFQEITVKEKGTIKLVARV-----------TRNPVPSITWYRNNEIISPSETIT 880
             P F    ++++V +  + K    V             +P P ITW R  E +     ++
Sbjct: 1456 IPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVS 1515

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940
                G+  ELVI   +   D G Y CVASN+ G       VT++ +    +    +S   
Sbjct: 1516 IQEFGQ--ELVIFAFEIS-DEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESING 1572

Query: 941  EEGKTVILECQTSHTVSTKWYHNK 964
            +E   + L C+ + T    +Y  K
Sbjct: 1573 DERIPLTLTCRATGTPEPTYYWEK 1596



 Score = 67.3 bits (157), Expect = 4e-09
 Identities = 96/445 (21%), Positives = 171/445 (38%), Gaps = 44/445 (9%)

Query: 509  APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF---RQTAIIKPSQD---FQMYYDD 562
            AP F      +    G +V  EC+ EG P P + WF   +  A  + ++D   +++   D
Sbjct: 1352 APYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGD 1411

Query: 563  DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622
              +AT+ I  +   D+  F C+A N   +    T +++                      
Sbjct: 1412 PQLATISITNLQTTDSNVFQCIATNM--YKEELTSVVLNV-------------FSIPASI 1456

Query: 623  XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682
                 +   +    +   K     EG  + +    V  P P I W    E++     +S+
Sbjct: 1457 PSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSI 1516

Query: 683  AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742
              E    +     +I++     EGTYT VA N  G+     V+ ++     PP ++E  +
Sbjct: 1517 Q-EFGQELVIFAFEISD-----EGTYTCVASNTGGDDEFSTVVTVEYDV--PPSIVEQPE 1568

Query: 743  SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVK 798
            S+   +   + L+ +  G P PT  W K+     AL      D  S+     +++     
Sbjct: 1569 SINGDERIPLTLTCRATGTPEPTYYWEKDG----ALFNVDSNDRVSLDGGNLVIESLTTA 1624

Query: 799  DEGVYTLKAENSEGIAETSAVITVEEPTE--ENAEPP-LFINRFQEITVKEKGTIKLVAR 855
            D+G Y   A+N  G A +  ++T     +  EN EP  + +++ Q + ++  G+  +   
Sbjct: 1625 DDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVP-- 1682

Query: 856  VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
                P P I W       +P     +        LV +NV +    G Y    +N  G S
Sbjct: 1683 -NGTPAPLIYWTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQAINNVVGSS 1741

Query: 916  SHGARVTIDVEKVTFVKH-LQKSYE 939
                +VT+ V     + H L + +E
Sbjct: 1742 QRSPKVTLRVRVDACLGHTLDQGWE 1766



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 81/332 (24%), Positives = 131/332 (39%), Gaps = 32/332 (9%)

Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688
           +  +PP+  ++P++   D+   + L CR   IPEP   W   G     D N   +++   
Sbjct: 27  IHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDGGN 86

Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIV 746
                 L I ++    +G Y   A NR       ++ + +    E  QV +  PLK   +
Sbjct: 87  ------LVIESLTTADDGQYQCFANNRL------VMDQFENTAWETIQVDQGRPLK---L 131

Query: 747 RQGESVILSAQVVGNPRPTITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
           R G S  +     GNP P + W        P+      S     S+          +G Y
Sbjct: 132 RCGGSPGVPN---GNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYY 188

Query: 804 TLKAENSEGIAETSAVITV---EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860
                N  G ++ S  +T+   + P  ++    +      EI ++ + + KL       P
Sbjct: 189 CQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQ-SFKLKCIAYGYP 247

Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            P ITW R  E +     I+    G+  ELVI+ V++  D G Y CVASN  G       
Sbjct: 248 TPEITWKRGEEQLQSGGRISIEESGQ--ELVISTVENS-DKGTYTCVASNCEGIDEFSTV 304

Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952
           VT  VE   +            G++V +EC++
Sbjct: 305 VT--VESAPYFPAPPSDETKRPGESVDIECRS 334



 Score = 62.9 bits (146), Expect = 9e-08
 Identities = 95/432 (21%), Positives = 157/432 (36%), Gaps = 36/432 (8%)

Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313
            ++   T D +     V++ A  T  L   + +FPP IV+        +   +TL      
Sbjct: 484  VVGSPTSDARALEKSVVIAATDTRTL---LDDFPPSIVEQPESVTGDQRIPLTLTCRAIG 540

Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373
             P+P   W  +  +     + + S+D    +L I+ +   D G Y+    N       E 
Sbjct: 541  TPEPAYYWEKDGALFDMDSNDRASLDG--GNLVIESLTTADDGQYQCFANNRLVMEQFEN 598

Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV-VEYQEIDTTEWISVKN 1432
                + + S  G+P  L    S          N   + +IY+     +    T    +  
Sbjct: 599  TAPAMVQLSQ-GQPLKLRCGGSP------GIPNGNPAPLIYWTDASPKHTSITYNARINQ 651

Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEV-DISDAS-----ETTEYYKVIKETKIQSPTVEK 1486
              +      N+  + +  +   A+N V  +   S       T+   V     + S     
Sbjct: 652  DLEGNLVFSNIIASDAKGYYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAAS 711

Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXX 1544
             + N T    +  +L CI  G P P +TW R  ++L++    +  E+             
Sbjct: 712  EVANRT----QSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEESGQALVISAVENSD 767

Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604
               Y C+A N  G+ E S VV ++  P       D K K   G+   +    EG+PPP V
Sbjct: 768  EGTYTCVASNTGGDDEFSTVVTVESAPYFLAPPSD-KTKGP-GESVDIECRSEGVPPPTV 825

Query: 1605 IWYKNGNKLENDKEYNITTKEKTSV--------IRIKELKRSHSSKYTIEASNTAGTSSV 1656
             W  NG     D E NI T+  T V        I I  L+ + S+ +   A+N       
Sbjct: 826  EWLVNGQTWA-DFESNIDTERWTVVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELT 884

Query: 1657 EVTLKVYDKPSK 1668
             V L V   P++
Sbjct: 885  SVVLNVVSFPAR 896



 Score = 62.5 bits (145), Expect = 1e-07
 Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 19/183 (10%)

Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796
           V +P  S I  + +S  L     G P P ITW +  + +++    S  ++    ++   +
Sbjct: 222 VTKPAASEIAIRTQSFKLKCIAYGYPTPEITWKRGEEQLQSGGRISIEESGQELVISTVE 281

Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856
             D+G YT  A N EGI E S V+TVE      A P        + T +   ++ +  R 
Sbjct: 282 NSDKGTYTCVASNCEGIDEFSTVVTVESAPYFPAPP-------SDETKRPGESVDIECRS 334

Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916
              P P++T   N +  + +ET     +G    LVI NV  ++DSG+Y+C A N+     
Sbjct: 335 KGVPAPTLT---NRDKYTVNET-----EG---SLVINNV-KKVDSGEYECRAENAIDGDD 382

Query: 917 HGA 919
           H A
Sbjct: 383 HEA 385



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 152/708 (21%), Positives = 261/708 (36%), Gaps = 93/708 (13%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--- 790
            PP ++E  +S+   Q   + L+ + +G P P   W K+     AL      D  S+    
Sbjct: 514  PPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDG----ALFDMDSNDRASLDGGN 569

Query: 791  -ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
             +++     D+G Y   A N            V E  E  A   + +++ Q + ++  G+
Sbjct: 570  LVIESLTTADDGQYQCFANNR----------LVMEQFENTAPAMVQLSQGQPLKLRCGGS 619

Query: 850  IKLVARVTRNPVPSITWYR---NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906
              +      NP P I W      +  I+ +  I Q+ +G    LV +N+ +  D+  Y C
Sbjct: 620  PGIP---NGNPAPLIYWTDASPKHTSITYNARINQDLEGN---LVFSNIIAS-DAKGYYC 672

Query: 907  VASNSA-GKSSHGARVTI---DVEKVTFVKHLQKSYETEE----GKTVILECQTSH--TV 956
            +A N+  G      ++ +   D+  V    HL       E     ++  L+C      T 
Sbjct: 673  LAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTP 732

Query: 957  STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTMLVV 1012
               W   ++++       I + G+            D G   C+      D E ST++ V
Sbjct: 733  VITWKRGEEQLQSGGRVSIEESGQALVISAVENS--DEGTYTCVASNTGGDDEFSTVVTV 790

Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETAD---VVWERDGEIIKPKKNKYDFEK-- 1067
             E+ P F+    D + K    ++ ++E  SE      V W  +G+     ++  D E+  
Sbjct: 791  -ESAPYFLAPPSD-KTKGPGESV-DIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWT 847

Query: 1068 ----RGHIRKLYIRNTSVHDEGEYSCIL----RDESCTAEVTVVELPPEI--ITRLQNQ- 1116
                   +  + I N    D   + CI     ++E  +  + VV  P  I   T L  + 
Sbjct: 848  VVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRL 907

Query: 1117 KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
             V + + A F      + D  + W   GS +  +N I+ TI+  +  L I +    D GE
Sbjct: 908  SVVEDDSAKFICHSRGRPDPTITWTFKGSVL--TNGIKYTINETEGSLVINNVKKVDGGE 965

Query: 1176 YSCEVGNS------KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETL--- 1225
            Y C   N+      + T   T+           P  +++     A    EI  DE L   
Sbjct: 966  YECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEELIEP 1025

Query: 1226 DVTWYKKKSVIEDTE-------KFTL----ISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274
             V W K    +E  +       +F      ++    R  I R   E  Q      LL   
Sbjct: 1026 YVYWMKDGQRLEANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEG 1085

Query: 1275 ST----TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330
             T    T+  +   + PP IV+        +   +TL       P+P   W  +  +   
Sbjct: 1086 RTRAHDTRRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNV 1145

Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378
              + + S+D    +L IK +   D G Y+   +N  G A  +  +T L
Sbjct: 1146 DSNDRVSLD--GGNLVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSL 1191



 Score = 55.2 bits (127), Expect = 2e-05
 Identities = 65/273 (23%), Positives = 102/273 (37%), Gaps = 25/273 (9%)

Query: 655  CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714
            C     P+P I W FKG  +     I   I          L I NVKK   G Y   A N
Sbjct: 919  CHSRGRPDPTITWTFKGSVLT--NGIKYTINETE----GSLVINNVKKVDGGEYECRAEN 972

Query: 715  R-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR---PTITWCK 770
              +GE          T   +    + P   MI R+G +     ++  +     P + W K
Sbjct: 973  AIDGEDYEATGSATLTMLGKTTIYLSPANLMI-REGNTATFQCEITYDEELIEPYVYWMK 1031

Query: 771  NNKPVKALPTKSDGDTHSITILKP-------KKVKDEGVYTLKAENSEGI---AETSAVI 820
            + + ++A      G    +  L P       + +    V  ++A   EG+     T A  
Sbjct: 1032 DGQRLEANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEGRTRAHD 1091

Query: 821  TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880
            T       N  PP  + + + I   ++  + L  R T  P P+  W ++  + +      
Sbjct: 1092 T-RRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1150

Query: 881  QNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
             + DG N  LVI ++ +  D G Y+C A N  G
Sbjct: 1151 VSLDGGN--LVIKSL-TTADDGQYQCFAKNRLG 1180



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 78/334 (23%), Positives = 122/334 (36%), Gaps = 34/334 (10%)

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI-CWD 1402
            L I  VEN+D G Y     N+ G  +    VT+   P  P  P +  +    S++I C  
Sbjct: 1317 LVISAVENSDEGTYTCVASNSGGDDEFSTVVTVESAPYFPYPPSDESKRPGESVDIEC-- 1374

Query: 1403 EPENTGNSTIIYYV-----VEYQ-EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYA 1455
              E     T+ ++V      +++   DT  W  V    +  T SI NL+T  S  F+  A
Sbjct: 1375 RSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGDPQLATISITNLQTTDSNVFQCIA 1434

Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG-------- 1507
             N        E T     +       P+     + ++   N+  + TC   G        
Sbjct: 1435 TNMY----KEELTSVVLNVFSIPASIPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKI 1490

Query: 1508 ---VPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562
                P P +TW R  ++L++    +  E                 Y C+A N  G+ E S
Sbjct: 1491 SVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVASNTGGDDEFS 1550

Query: 1563 CVVGIQQ--KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
             VV ++    P I    E I    ++     +T    G P P   W K+G     D    
Sbjct: 1551 TVVTVEYDVPPSIVEQPESINGDERI--PLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1608

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654
            ++      V  I+ L  +   +Y   A N  GT+
Sbjct: 1609 VSLDGGNLV--IESLTTADDGQYQCFAKNRLGTA 1640



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 19/158 (12%)

Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712
           L+C     P P+I W    E++     IS+  ES        L I+ V+   +GTYT VA
Sbjct: 239 LKCIAYGYPTPEITWKRGEEQLQSGGRISIE-ESGQE-----LVISTVENSDKGTYTCVA 292

Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772
            N EG      V+ +++     P    P      R GESV +  +  G P PT+T    N
Sbjct: 293 SNCEGIDEFSTVVTVESA----PYFPAPPSDETKRPGESVDIECRSKGVPAPTLT----N 344

Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810
           +  K    +++G   S+ I   KKV D G Y  +AEN+
Sbjct: 345 RD-KYTVNETEG---SLVINNVKKV-DSGEYECRAENA 377



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 78/385 (20%), Positives = 135/385 (35%), Gaps = 29/385 (7%)

Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340
            V + + PP IV+        +   +TL       P+P   W  +  +     + + S+D 
Sbjct: 25   VPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDG 84

Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400
               +L I+ +   D G Y+    NN    D   N          G+P  L    S     
Sbjct: 85   --GNLVIESLTTADDGQYQC-FANNRLVMDQFENTAWETIQVDQGRPLKLRCGGSP---- 137

Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNE 1458
               P   GN   + Y  +     T    + +     + S+   N+  + +  +   A+N 
Sbjct: 138  -GVPN--GNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINN 194

Query: 1459 V--DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516
            V      + + T     +      +  V KP  +      +  +L CI  G P P++TW 
Sbjct: 195  VVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK 254

Query: 1517 RDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574
            R  ++L++    +  E+                Y C+A N  G  E S VV ++  P   
Sbjct: 255  RGEEQLQSGGRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTVVTVESAPYFP 314

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634
                D  +  + G+   +    +G+P P          L N  +Y +   E + V  I  
Sbjct: 315  APPSD--ETKRPGESVDIECRSKGVPAP---------TLTNRDKYTVNETEGSLV--INN 361

Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVT 1659
            +K+  S +Y   A N       E T
Sbjct: 362  VKKVDSGEYECRAENAIDGDDHEAT 386



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 42/192 (21%), Positives = 70/192 (36%), Gaps = 15/192 (7%)

Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR-------- 1532
            +P    P  + T  P E +++ C   GVP P V W  +G+     ++  +          
Sbjct: 793  APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGD 852

Query: 1533 ---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589
                              ++CIA N + E  TS V+ +   P    S   + ++  V ++
Sbjct: 853  PQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRLSVVED 912

Query: 1590 WLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647
                 +    G P P + W   G+ L N  +Y I   E + V  I  +K+    +Y   A
Sbjct: 913  DSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLV--INNVKKVDGGEYECRA 970

Query: 1648 SNTAGTSSVEVT 1659
             N       E T
Sbjct: 971  ENAIDGEDYEAT 982



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
           + +C   GYP P+ITW R    ++      +   +++   LVI  V   D GT+TCVA N
Sbjct: 238 KLKCIAYGYPTPEITWKRGEEQLQSGGRISI---EESGQELVISTVENSDKGTYTCVASN 294

Query: 588 AAGFASSTTELIVEA 602
             G    +T + VE+
Sbjct: 295 CEGIDEFSTVVTVES 309



 Score = 45.6 bits (103), Expect = 0.015
 Identities = 70/296 (23%), Positives = 110/296 (37%), Gaps = 26/296 (8%)

Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEID 1393
            SI+    +L I  VEN+D G Y     N  G  +    VT+   P   +PP        +
Sbjct: 750  SIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYFLAPPSDKTKGPGE 809

Query: 1394 SSSINICWDEPENTGNSTIIYYV-----VEYQ-EIDTTEWISVKNITKTQT-SIQNLKTN 1446
            S  I  C    E     T+ + V      +++  IDT  W  V    +  T +I NL+T 
Sbjct: 810  SVDIE-C--RSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLATIAITNLQTT 866

Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506
             S  F+  A N+       E T     +     +  +     + ++   ++  +  C   
Sbjct: 867  DSNVFQCIATNKY----KEELTSVVLNVVSFPARITSFTPLTRRLSVVEDDSAKFICHSR 922

Query: 1507 GVPQPKVTWYRDGKKLKTA-KATY-ENRXXXXXXXXXXXXXXXYKCIAFN----DHGEVE 1560
            G P P +TW   G  L    K T  E                 Y+C A N    +  E  
Sbjct: 923  GRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAENAIDGEDYEAT 982

Query: 1561 TSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614
             S  + +  K  I +S  N  I++ +    +  +T   E +  P V W K+G +LE
Sbjct: 983  GSATLTMLGKTTIYLSPANLMIREGNTATFQCEIT-YDEELIEPYVYWMKDGQRLE 1037



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 27/145 (18%), Positives = 59/145 (40%), Gaps = 3/145 (2%)

Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825
           + +C+    +  L          + I+ P +    GV      ++  + ++  +   +  
Sbjct: 448 LDFCQARYDIHCLDPGPSKGAIGLPIISPHRRMKAGVVGSPTSDARALEKSVVIAATDTR 507

Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885
           T  +  PP  + + + +T  ++  + L  R    P P+  W ++  +         + DG
Sbjct: 508 TLLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG 567

Query: 886 ENIELVITNVDSEIDSGDYKCVASN 910
            N  LVI ++ +  D G Y+C A+N
Sbjct: 568 GN--LVIESL-TTADDGQYQCFANN 589



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 13/194 (6%)

Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659
            P P + W +   +L++    +I   E    + I  ++ S    YT  ASN+ G       
Sbjct: 1291 PTPVITWKRGEEQLQSGGRVSIHEHE----LVISAVENSDEGTYTCVASNSGGDDEFSTV 1346

Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWK-----PPLDDGGLELTKYAIEKHEPDNNRWI 1714
            + V   P  P  P    +   ESV IE +      P  D  +    +A  +   D  RW 
Sbjct: 1347 VTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERW- 1405

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI-VIKTALDVPSXXXXX 1773
            +V   D  + T  I  L      +F+ IA N   + E L S  + V      +PS     
Sbjct: 1406 EVVTGDPQLATISITNLQTTDSNVFQCIATNM--YKEELTSVVLNVFSIPASIPSFTPLT 1463

Query: 1774 XXXXXIDNESVYIT 1787
                 + N+S   T
Sbjct: 1464 RKLSVVQNDSAKFT 1477



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587
           + +C   GYP P ITW R    ++      +   +++   LVI  V   D GT+TCVA N
Sbjct: 721 KLKCIAFGYPTPVITWKRGEEQLQSGGRVSI---EESGQALVISAVENSDEGTYTCVASN 777

Query: 588 AAGFASSTTELIVEA 602
             G    +T + VE+
Sbjct: 778 TGGDDEFSTVVTVES 792



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%)

Query: 813 IAETSAVITVEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871
           I E    I  ++PT    + PP  + + + I   ++  + L  R T  P P+  W ++  
Sbjct: 11  IVEQPESINGDQPTVPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGS 70

Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910
           +         + DG N  LVI ++ +  D G Y+C A+N
Sbjct: 71  LFDVDSNDRASLDGGN--LVIESL-TTADDGQYQCFANN 106



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 6/85 (7%)

Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF--RQT-AIIKPSQDFQMY---YDD 562
           AP F+     K    G +V  EC+ EG P P + W    QT A  + + D + +     D
Sbjct: 793 APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGD 852

Query: 563 DNVATLVIREVFPEDAGTFTCVAKN 587
             +AT+ I  +   D+  F C+A N
Sbjct: 853 PQLATIAITNLQTTDSNVFQCIATN 877



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 3/97 (3%)

Query: 498  FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557
            F    + E  + P  VE+    +  +   +   C+  G P P   W +  A+     + +
Sbjct: 1549 FSTVVTVEYDVPPSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1608

Query: 558  MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
            +  D  N   LVI  +   D G + C AKN  G A S
Sbjct: 1609 VSLDGGN---LVIESLTTADDGQYQCFAKNRLGTAMS 1642



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 2/89 (2%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657
            G P PE+ W +   +L++    +I  +E    + I  ++ S    YT  ASN  G     
Sbjct: 245  GYPTPEITWKRGEEQLQSGGRISI--EESGQELVISTVENSDKGTYTCVASNCEGIDEFS 302

Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIE 1686
              + V   P  P  P    +   ESV IE
Sbjct: 303  TVVTVESAPYFPAPPSDETKRPGESVDIE 331



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 23/208 (11%)

Query: 734  PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--- 790
            PP ++E  +S+   Q   + L+ +  G P PT  W K+     AL      D  S+    
Sbjct: 1102 PPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDG----ALFNVDSNDRVSLDGGN 1157

Query: 791  -ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE--ENAEPP-LFINRFQEITVKE 846
             ++K     D+G Y   A+N  G A +  ++T     +  EN EP  + + R + + +  
Sbjct: 1158 LVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENTEPAWIQVRRGRPLKLLC 1217

Query: 847  KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGENIELVITNVDSEIDSG 902
             G+  +      NP P I W   N    P+  IT N     D E   LV ++  +  D+ 
Sbjct: 1218 GGSPGI---PNGNPAPLIYW--TNAAAKPT-PITYNARIAQDPEG-NLVFSHAIAS-DAQ 1269

Query: 903  DYKCVASNSAGKSSHGARVTIDVEKVTF 930
             Y C A N+   SS    +      +T+
Sbjct: 1270 GYYCQAINNIVGSSQRTPIISPTPVITW 1297



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 15/153 (9%)

Query: 632  IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
            +PP+  ++P++   D+   + L CR    PEP   W   G     D N  V+++      
Sbjct: 1101 VPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDG----- 1155

Query: 692  CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751
               L I ++    +G Y   A NR G A    +L       +  +  EP   + VR+G  
Sbjct: 1156 -GNLVIKSLTTADDGQYQCFAKNRLGTAMSQKIL-TSLAFMDQFENTEP-AWIQVRRGRP 1212

Query: 752  VIL----SAQVV-GNPRPTITWCKNNKPVKALP 779
            + L    S  +  GNP P I W   N   K  P
Sbjct: 1213 LKLLCGGSPGIPNGNPAPLIYW--TNAAAKPTP 1243



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 531  CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590
            C+  G P P   W +  A+     + ++  D  N   LVI+ +   D G + C AKN  G
Sbjct: 1124 CRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGN---LVIKSLTTADDGQYQCFAKNRLG 1180

Query: 591  FASS 594
             A S
Sbjct: 1181 TAMS 1184


>UniRef50_UPI00015A6655 Cluster: myomesin family, member 3; n=6; Danio
            rerio|Rep: myomesin family, member 3 - Danio rerio
          Length = 1172

 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 91/395 (23%), Positives = 154/395 (38%), Gaps = 46/395 (11%)

Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662
            +V WY++G  +       + T  +++ + +K + + H   YT+      GT  VE +  V
Sbjct: 39   DVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGT--VEHSAYV 96

Query: 1663 YDKPSK------PEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714
            Y K         P  P+ ++  +++R+ V + W PP  DG   +  Y IE+ +    +W 
Sbjct: 97   YVKDGSAVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWE 156

Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQN------------PVGFSEALE-SEPIVIK 1761
            +  DV + V  Y +  L EN  Y FRV A N            P+  S+ LE S  +V+K
Sbjct: 157  RCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVK 216

Query: 1762 TA---------------LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806
                             + VP            D  +V + W   +  G  P+  Y VE 
Sbjct: 217  VERGRQIVITKDQLEGQIRVPFPPTEVQVCELSDTYAV-LRWTEPDPRGREPL-KYFVER 274

Query: 1807 KQEG-KKWKXXXXXXXXXA-RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKT 1862
               G + W          + R          +Y +R+ + N+ G S P      I++G+ 
Sbjct: 275  SISGTESWHLASMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQP 334

Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922
               P+ P   +    T+ SV L+W EP    G  I  Y +         W  I     + 
Sbjct: 335  QGVPAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITT 392

Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957
                ++ +K   + +FR+ +    G S+ +E   V
Sbjct: 393  TRFTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPV 427



 Score = 75.4 bits (177), Expect = 2e-11
 Identities = 69/296 (23%), Positives = 120/296 (40%), Gaps = 38/296 (12%)

Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTY 1835
            ++ + V+++W P   +G + +  Y +E    G  KW+          +  +  L  NT Y
Sbjct: 120  VNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMY 179

Query: 1836 QFRIYARNEIGTSLP-------YTSDD---------KITIGKTLT-----------PPSQ 1868
            QFR+ A N+ G   P        TSD          K+  G+ +             P  
Sbjct: 180  QFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVKVERGRQIVITKDQLEGQIRVPFP 239

Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW--TKIVTVGGSVHEHC 1926
            P    V E +     L+WTEP+  G  P+  Y +E      +SW    +     S     
Sbjct: 240  PTEVQVCELSDTYAVLRWTEPDPRGREPL-KYFVERSISGTESWHLASMDMTVLSTRFSA 298

Query: 1927 IENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985
             +  K K    +R+ + N  G+S P+  S+ + L +   VP+PP+  L +R   S++++ 
Sbjct: 299  FDQQKGK-SYSYRVRSVNKYGISEPSLPSKPISLGQPQGVPAPPSGVLPMRDTNSSVLL- 356

Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041
             W  P    G  ++GY +   +     W  +    + T +F +  L  N  Y+ R+
Sbjct: 357  QWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRFTVDGLKSNKQYVFRV 410



 Score = 63.3 bits (147), Expect = 7e-08
 Identities = 27/83 (32%), Positives = 44/83 (53%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T  ++G P PE+ W KN  ++ +  +YNI  + K+S + I  +    S  Y+I   N  
Sbjct: 1088 LTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSMEDSGNYSIFVRNKH 1147

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVI 1674
            G+ +V VT+ VY    KP G  +
Sbjct: 1148 GSQTVLVTVSVYKHGEKPRGDAV 1170



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%)

Query: 1299 IKRGSDVTLLVDYQAFPQPNDE---WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355
            +K G ++ L   +     P  +   W  +   ++     +     +SASLT+K V     
Sbjct: 17   VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHE 76

Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSIN-----ICWDEPEN 1406
            G+Y +RL    G  +    V + D  +     PG P  L++  S +N     + W  P  
Sbjct: 77   GLYTVRLRTWDGTVEHSAYVYVKDGSAVVVGAPGSP--LQVKCSDVNRDYVFLSWIPPSA 134

Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
             G + +  Y +E  +I   +W    ++ +   Q  +  LK N+ Y+FR  AVN+  +   
Sbjct: 135  DGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRP 194

Query: 1465 SETTE 1469
            S+ +E
Sbjct: 195  SKPSE 199



 Score = 53.6 bits (123), Expect = 6e-05
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%)

Query: 1963 ATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020
            A V   P +PL+++   V  + V  SW  P  DG A + GY I   D+    W     V 
Sbjct: 103  AVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVI 162

Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058
                ++ +  L EN  Y  R+ A N+ G+  P +  EP
Sbjct: 163  QKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEP 200



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 49/231 (21%), Positives = 91/231 (39%), Gaps = 33/231 (14%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925
            P  P     S+     V L W  P ++G + +  Y IE   +    W +   V   V ++
Sbjct: 109  PGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQY 168

Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE---------------SQSVRLEKHATV----- 1965
             +  +KE     FR+ A N  GV  P++               +  V++E+   +     
Sbjct: 169  PVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVKVERGRQIVITKD 228

Query: 1966 --------PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017
                    P PPT  +++  +     +  W  P+  G  PL  +    R ++ T    + 
Sbjct: 229  QLEGQIRVPFPPT-EVQVCELSDTYAVLRWTEPDPRGREPLKYF--VERSISGTESWHLA 285

Query: 2018 KVDVNTL--KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066
             +D+  L  +F+  D  +  +Y  R+ + N+ G+SEP    +P  +   +G
Sbjct: 286  SMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQPQG 336



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438
            P+PP     +   +SS+ + W EP  T    I+ Y +   E  + +W ++ N  IT T+ 
Sbjct: 338  PAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRF 395

Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473
            ++  LK+N  Y FR  +V     S  SE +   +V
Sbjct: 396  TVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRV 430



 Score = 41.9 bits (94), Expect = 0.19
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 4/101 (3%)

Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725
            P+ P G + MR+ +  SV ++WK P    G+    Y +   E  + +W  + +       
Sbjct: 338  PAPPSGVLPMRD-TNSSVLLQWKEPAVTEGI--VGYYLYCSEAGSGQWKTINNKPITTTR 394

Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALD 1765
            + +  L  N +Y+FRV +    G S   E  P++ +K AL+
Sbjct: 395  FTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRVKAALN 435



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNIT--KTQ 1437
            P PP +  + E+  +   + W EP+  G   + Y+ VE     T  W ++  ++T   T+
Sbjct: 237  PFPPTEVQVCELSDTYAVLRWTEPDPRGREPLKYF-VERSISGTESWHLASMDMTVLSTR 295

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465
             S  + +   SY +R  +VN+  IS+ S
Sbjct: 296  FSAFDQQKGKSYSYRVRSVNKYGISEPS 323



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/107 (21%), Positives = 54/107 (50%), Gaps = 5/107 (4%)

Query: 726  KIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TK 781
            +++  EK   +V + L  ++ + + +S+ L+  V G+P P + W KN++ + +      K
Sbjct: 1059 QVEFAEKNRARVTKGLPDVVAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIK 1118

Query: 782  SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828
            ++  + ++TI     ++D G Y++   N  G       ++V +  E+
Sbjct: 1119 NENKSSTLTI-NHVSMEDSGNYSIFVRNKHGSQTVLVTVSVYKHGEK 1164



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%)

Query: 842  ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901
            + + E  ++ L   V  +P P + W +N+  IS +       + ++  L I +V  E DS
Sbjct: 1078 VAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSME-DS 1136

Query: 902  GDYKCVASNSAGKSSHGARVTIDVEK 927
            G+Y     N  G  S    VT+ V K
Sbjct: 1137 GNYSIFVRNKHG--SQTVLVTVSVYK 1160


>UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 253

 Score = 89.4 bits (212), Expect = 9e-16
 Identities = 69/269 (25%), Positives = 119/269 (44%), Gaps = 24/269 (8%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G +    CR+  IP+PDI W + G  +    N++    S ++    V  + N  ++ EG+
Sbjct: 3   GKNFTFTCRVEGIPKPDIKWKYNGGPL----NLA---HSTINNTLVVFNVQNTDRY-EGS 54

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766
           Y   A +R G AS    L +       P++ + L K+++  +G +V LS Q  G+P P  
Sbjct: 55  YECEASSRAGNASSSASLTVYA----LPKITKLLNKTLVAERGSNVQLSCQASGDPTPKY 110

Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826
            W     P+         D + + ILK       GVY   A N+EG   T   + V    
Sbjct: 111 KWTYKGVPISPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIV---- 166

Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE----TITQN 882
             +    + +   +++   E   + L       P+P++TWY  ++II+ ++    +IT N
Sbjct: 167 --HVSVGIVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNN 224

Query: 883 FDGENIELVITNVDSEI-DSGDYKCVASN 910
             G  +E  +   ++   D G+Y CV  N
Sbjct: 225 VSGVRLESTLRLNNTRFGDRGNYSCVFKN 253



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 19/153 (12%)

Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700
           K    + GS++ L C+    P P   W +KG  I P EN  V +E D  +    L +  V
Sbjct: 86  KTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPREN--VQLEDDNRL----LILKKV 139

Query: 701 KKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQ 757
                G Y  +A N EG       +++ +  G      ++ PL + +I  +G+ + L+  
Sbjct: 140 SPVSNGVYRCIAYNAEGNDTTETKLIVHVSVG------IVVPLPEKVIFMEGQPLNLTCA 193

Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790
             G P P +TW   +K +    T++DG  +SIT
Sbjct: 194 AEGIPLPNVTWYHYDKII----TQTDGSRYSIT 222



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           GS VQ  CQ  G P P+  W  +   I P ++ Q+  +DDN   L++++V P   G + C
Sbjct: 93  GSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQL--EDDN-RLLILKKVSPVSNGVYRC 149

Query: 584 VAKNAAGFASSTTELIV 600
           +A NA G  ++ T+LIV
Sbjct: 150 IAYNAEGNDTTETKLIV 166



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 65/253 (25%), Positives = 104/253 (41%), Gaps = 24/253 (9%)

Query: 855  RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV-DSEIDSGDYKCVASNSAG 913
            RV   P P I W  N   ++ + +   N       LV+ NV +++   G Y+C AS+ AG
Sbjct: 11   RVEGIPKPDIKWKYNGGPLNLAHSTINN------TLVVFNVQNTDRYEGSYECEASSRAG 64

Query: 914  KSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGM 970
             +S  A +T+  + K+T  K L K+   E G  V L CQ S   T   KW +    IS  
Sbjct: 65   NASSSASLTVYALPKIT--KLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPR 122

Query: 971  DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDF 1026
            ++ ++  + R              GV +CI  + E    T T L+V  ++   +   +  
Sbjct: 123  ENVQLEDDNRLLILKKVSPVSN--GVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKV 180

Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEII-KPKKNKYDFEKR-GHIR---KLYIRNTS 1080
               E     L          +V W    +II +   ++Y        +R    L + NT 
Sbjct: 181  IFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTR 240

Query: 1081 VHDEGEYSCILRD 1093
              D G YSC+ ++
Sbjct: 241  FGDRGNYSCVFKN 253



 Score = 50.8 bits (116), Expect = 4e-04
 Identities = 37/167 (22%), Positives = 66/167 (39%), Gaps = 8/167 (4%)

Query: 1482 PTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXX 1538
            P + K L K +  E   +++L+C   G P PK  W   G  +   +     ++       
Sbjct: 78   PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK 137

Query: 1539 XXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                     Y+CIA+N  G    ET  +V +    V+ +  + I  +   G    +T   
Sbjct: 138  KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKVIFME---GQPLNLTCAA 194

Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            EGIP P V WY     +        +     S +R++   R +++++
Sbjct: 195  EGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRF 241



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 36/168 (21%), Positives = 69/168 (41%), Gaps = 5/168 (2%)

Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556
            ++   TC   G+P+P + W  +G  L  A +T  N                Y+C A +  
Sbjct: 4    KNFTFTCRVEGIPKPDIKWKYNGGPLNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRA 63

Query: 1557 GEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615
            G   +S  + +   P IT + N+ +  +   G    ++    G P P+  W   G  + +
Sbjct: 64   GNASSSASLTVYALPKITKLLNKTLVAER--GSNVQLSCQASGDPTPKYKWTYKGVPI-S 120

Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663
             +E N+  ++   ++ +K++    +  Y   A N  G  + E  L V+
Sbjct: 121  PRE-NVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVH 167



 Score = 44.4 bits (100), Expect = 0.035
 Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 22/242 (9%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192
            ++W  +G  +  ++    TI+       + + D  + G Y CE     GN+  +A LTV 
Sbjct: 20   IKWKYNGGPLNLAHS---TINNTLVVFNVQNTDRYE-GSYECEASSRAGNASSSASLTVY 75

Query: 1193 E-PSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKK 1250
              P I  T  L + ++    ++  L+ +   D T    W  K   I   E   L  D   
Sbjct: 76   ALPKI--TKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDD--N 131

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308
            R LI++K +      Y C+  +A+   TT+ K+ V      +V    +     G  + L 
Sbjct: 132  RLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKVIFMEGQPLNLT 191

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK---KVENT---DAGIYKLRL 1362
               +  P PN  W    KII +   ++ SI +  + + ++   ++ NT   D G Y    
Sbjct: 192  CAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVF 251

Query: 1363 EN 1364
            +N
Sbjct: 252  KN 253



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 4/81 (4%)

Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645
            VG  +  T  +EGIP P++ W  NG  L      + T      V  ++   R +   Y  
Sbjct: 2    VGKNFTFTCRVEGIPKPDIKWKYNGGPL---NLAHSTINNTLVVFNVQNTDR-YEGSYEC 57

Query: 1646 EASNTAGTSSVEVTLKVYDKP 1666
            EAS+ AG +S   +L VY  P
Sbjct: 58   EASSRAGNASSSASLTVYALP 78



 Score = 40.7 bits (91), Expect = 0.43
 Identities = 51/222 (22%), Positives = 94/222 (42%), Gaps = 18/222 (8%)

Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA--GIYK 1359
            G + T     +  P+P+ +W  N   +     T   I++   +L +  V+NTD   G Y+
Sbjct: 3    GKNFTFTCRVEGIPKPDIKWKYNGGPLNLAHST---INN---TLVVFNVQNTDRYEGSYE 56

Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY-YVVE 1418
                +  G+A    ++T+   P      N   +     N+     + +G+ T  Y +  +
Sbjct: 57   CEASSRAGNASSSASLTVYALPKITKLLNKTLVAERGSNVQLS-CQASGDPTPKYKWTYK 115

Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478
               I   E + +++  +    ++ +   S+  +R  A N    ++ ++TTE  K+I    
Sbjct: 116  GVPISPRENVQLEDDNRLLI-LKKVSPVSNGVYRCIAYN----AEGNDTTET-KLIVHVS 169

Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            +    V  P K I  E  + + LTC   G+P P VTWY   K
Sbjct: 170  V-GIVVPLPEKVIFME-GQPLNLTCAAEGIPLPNVTWYHYDK 209



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%)

Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV------ATLVIREVFPE 576
           +G  +   C  EG P P +TW+    II  + D   Y   +NV      +TL +      
Sbjct: 184 EGQPLNLTCAAEGIPLPNVTWYHYDKIITQT-DGSRYSITNNVSGVRLESTLRLNNTRFG 242

Query: 577 DAGTFTCVAKN 587
           D G ++CV KN
Sbjct: 243 DRGNYSCVFKN 253


>UniRef50_UPI0000F2C7E8 Cluster: PREDICTED: similar to myomesin 1;
            n=1; Monodelphis domestica|Rep: PREDICTED: similar to
            myomesin 1 - Monodelphis domestica
          Length = 1245

 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%)

Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG---KSWTKIVT 1917
            K +  PS P +    ES   S+ L W +PE  GG+ IT Y + ++ V G     W +   
Sbjct: 922  KAVAAPSPPYDITCLESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKWKEANI 981

Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHA-TVPSPPTAPLEI 1975
               S   + I N+KE     F+++A N  GV  P++ S S + E+    VP PP   L+ 
Sbjct: 982  KAVSDQAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFKCEEWTIAVPGPPHG-LKY 1040

Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD--VTKTMWMEVGKVDVNTLKFNIRDLSE 2033
              V    ++  W  P + G  P+ G+ + +++       W  + +  +      +++L E
Sbjct: 1041 SEVRKTSLVLQWKHPVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNTYLKVQNLKE 1100

Query: 2034 NHTYMIRIYARNEIGLSEPLESDEP 2058
              +YM R+ A N+ G+ +P +   P
Sbjct: 1101 GVSYMFRVRALNQAGVGKPSDIAGP 1125



 Score = 64.5 bits (150), Expect = 3e-08
 Identities = 51/198 (25%), Positives = 79/198 (39%), Gaps = 6/198 (3%)

Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHE 1924
            P  P +  V+EST   V L W  P   G   I  Y +E      ++W ++ T +      
Sbjct: 590  PGPPTDLSVTESTRSYVVLSWKPPGQRGHEGIM-YFVEKCVADTENWQRVNTEIPVKSPR 648

Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIV 1983
              + ++ E     FR+   N+ GV  P+E+  V  +     +P  P   +  R   +++V
Sbjct: 649  FALFDLAEGKSYRFRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDTSVV 708

Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043
            +T W   E      L+GY I    V    W       V   +F    L     Y+ R+ A
Sbjct: 709  VT-W--EESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRA 765

Query: 2044 RNEIGLSEPLESDEPFKV 2061
             N  GLSE  +  E  +V
Sbjct: 766  VNAAGLSEYSQDSEAIEV 783



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727
            P   + + E +R  V + WKPP    G E   Y +EK   D   W +V  ++      + 
Sbjct: 592  PPTDLSVTESTRSYVVLSWKPP-GQRGHEGIMYFVEKCVADTENWQRVNTEIPVKSPRFA 650

Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPI-VIKTALDVPSXXXXXXXXXXIDNESVYI 1786
            +  L E   Y FRV   N  G  E  E+  + V+   LD+P            D  SV +
Sbjct: 651  LFDLAEGKSYRFRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDT-SVVV 709

Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI--QKLSINTTYQFRIYARN 1843
            TW   E      ++ Y +E    G  +W+         +R     L     Y FR+ A N
Sbjct: 710  TW--EESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRAVN 767

Query: 1844 EIGTSLPYTSDDK 1856
              G S  Y+ D +
Sbjct: 768  AAGLS-EYSQDSE 779



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEW--ISVKNITK 1435
            PSPP     LE    S+ + W +PE TG + I  Y V Y+E+      +W   ++K ++ 
Sbjct: 927  PSPPYDITCLESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKWKEANIKAVSD 986

Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472
                I NLK N  Y+F+  AVN   +   S+ +  +K
Sbjct: 987  QAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFK 1023



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 58/245 (23%), Positives = 94/245 (38%), Gaps = 15/245 (6%)

Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676
            KE + TT ++      +  K +   K   E +  A T       K    PS P   +   
Sbjct: 879  KEVSETTVQEALAPLAEPQKAADQGKSKSEPAAPA-TLEKGKKKKAVAAPSPPYD-ITCL 936

Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN---NRWIKVADVDR-DVETYCIQKLN 1732
            E  R+S+ + WK P   GG E+T Y +   E       +W K A++     + Y I  L 
Sbjct: 937  ESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKW-KEANIKAVSDQAYKISNLK 995

Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPI--VIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790
            EN  Y F+V A N  G     +        +  + VP           +   S+ + W  
Sbjct: 996  ENMIYQFQVAAVNLAGVGTPSQPSASFKCEEWTIAVPG-PPHGLKYSEVRKTSLVLQWKH 1054

Query: 1791 SEKNGGSPIIDYKVEIKQEGKK---WKXXXXXX--XXXARIQKLSINTTYQFRIYARNEI 1845
               +G +P+  + V++K+   K   W+            ++Q L    +Y FR+ A N+ 
Sbjct: 1055 PVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNTYLKVQNLKEGVSYMFRVRALNQA 1114

Query: 1846 GTSLP 1850
            G   P
Sbjct: 1115 GVGKP 1119



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 4/113 (3%)

Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010
            P   +  + +K    PSPP     +     ++V+  W  PE  GGA + GY +  R+V  
Sbjct: 912  PATLEKGKKKKAVAAPSPPYDITCLESFRDSMVL-GWKQPEKTGGAEITGYYVNYREVIG 970

Query: 2011 TM---WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060
             +   W E     V+   + I +L EN  Y  ++ A N  G+  P +    FK
Sbjct: 971  GVPGKWKEANIKAVSDQAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFK 1023



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 10/142 (7%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--W--ISVKNITKT 1436
            P PP      E+  +S+ + W  P  +G + +  + V+ +E    +  W  I+ K I  T
Sbjct: 1032 PGPPHGLKYSEVRKTSLVLQWKHPVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNT 1091

Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496
               +QNLK   SY FR  A+N+  +   S+      ++ ET+   P  ++ + N+  +  
Sbjct: 1092 YLKVQNLKEGVSYMFRVRALNQAGVGKPSDIAG--PIVAETR---PGTKEIVINVDDDGV 1146

Query: 1497 EDIELTCIFGGVPQPKVTWYRD 1518
              +   C     P  K  W +D
Sbjct: 1147 ISLNFECDQMS-PDSKFVWSKD 1167



 Score = 45.2 bits (102), Expect = 0.020
 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 4/92 (4%)

Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437
            P PP   ++ E   S + + W  P   G+  I+Y+ VE    DT  W  V     +   +
Sbjct: 590  PGPPTDLSVTESTRSYVVLSWKPPGQRGHEGIMYF-VEKCVADTENWQRVNTEIPVKSPR 648

Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
             ++ +L    SYRFR    N   + + SE T+
Sbjct: 649  FALFDLAEGKSYRFRVRCSNSAGVGEPSEATD 680



 Score = 43.6 bits (98), Expect = 0.061
 Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 6/114 (5%)

Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661
            PEV WY+NG  +   K          + +    L +     YT+              + 
Sbjct: 351  PEVQWYRNGTLVSPSKWVQTQWSGDRATLTFSHLNKEDEGLYTLRVRMGEYYEQYSAYVF 410

Query: 1662 VYDKPSK----PEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709
            V D  ++    P  P  V+  + +++ V I WK P  DGG  +  Y I+K E +
Sbjct: 411  VRDADAEIAGAPASPLDVVCLDANKDYVIISWKQPAVDGGSPILGYFIDKEEQE 464



 Score = 43.2 bits (97), Expect = 0.081
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%)

Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVK 798
           R+GE++ L  +VV  P     +P + W +N     P K + T+  GD  ++T     K +
Sbjct: 329 REGETMSLGCRVVITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDRATLTFSHLNK-E 387

Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833
           DEG+YTL+    E   + SA + V +   E A  P
Sbjct: 388 DEGLYTLRVRMGEYYEQYSAYVFVRDADAEIAGAP 422



 Score = 42.3 bits (95), Expect = 0.14
 Identities = 35/147 (23%), Positives = 61/147 (41%), Gaps = 10/147 (6%)

Query: 1284 VEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341
            + F  K  V + RE   +  G  V +  + + F QP  +W  N  ++   K  +      
Sbjct: 317  IHFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEVQWYRNGTLVSPSKWVQTQWSGD 375

Query: 1342 SASLTIKKVENTDAGIYKLRL------ENNCGHADV-EMNVTILDKPSPPGKPNILEIDS 1394
             A+LT   +   D G+Y LR+      E    +  V + +  I   P+ P     L+ + 
Sbjct: 376  RATLTFSHLNKEDEGLYTLRVRMGEYYEQYSAYVFVRDADAEIAGAPASPLDVVCLDANK 435

Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQE 1421
              + I W +P   G S I+ Y ++ +E
Sbjct: 436  DYVIISWKQPAVDGGSPILGYFIDKEE 462



 Score = 41.1 bits (92), Expect = 0.33
 Identities = 52/238 (21%), Positives = 87/238 (36%), Gaps = 26/238 (10%)

Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546
           L + +++   F +  +E+  + AP FV K R     +   V+  C V G+P P++TW++ 
Sbjct: 168 LRKTLEETEEFHRKLNEDSLLHAPEFVIKPRSHTVWEKQNVRLHCSVSGWPEPRLTWYKN 227

Query: 547 TAII----KPSQ-----DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597
              I     P +      + M+Y + N  T       P        +  N A       E
Sbjct: 228 HVPINVHANPGKYIIESRYGMHYLEINADTQGPEGKKPNACWGRPPLTANPAAMKGYKGE 287

Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657
              E       S M +             +I       F  K    +  EG  + L CR+
Sbjct: 288 -YDETRFHAGASTMPLSFGVTPYGFASKFEI------HFDDKFDVSFGREGETMSLGCRV 340

Query: 658 VAIPE-----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710
           V  PE     P++ W   G  + P + +      D     + L  +++ K  EG YT+
Sbjct: 341 VITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDR----ATLTFSHLNKEDEGLYTL 394



 Score = 40.3 bits (90), Expect = 0.57
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%)

Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG-KVDVNT 2023
            VP PPT  L +     + V+ SW  P   G   ++ Y +         W  V  ++ V +
Sbjct: 589  VPGPPT-DLSVTESTRSYVVLSWKPPGQRGHEGIM-YFVEKCVADTENWQRVNTEIPVKS 646

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057
             +F + DL+E  +Y  R+   N  G+ EP E+ +
Sbjct: 647  PRFALFDLAEGKSYRFRVRCSNSAGVGEPSEATD 680



 Score = 39.9 bits (89), Expect = 0.75
 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%)

Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184
            FE +    D+   W KD   ++ S  +Q+   G K K    D  +DD G YSC+V ++  
Sbjct: 1151 FECDQMSPDSKFVWSKDYVPVEDSPRLQVDTKGNKTKTTFKDLGIDDLGIYSCDVTDTDG 1210

Query: 1185 CTAILTVEEPSINFTLRLPE 1204
              A   ++E  +   L L +
Sbjct: 1211 IAASYLIDEEEMKRLLALSQ 1230



 Score = 38.7 bits (86), Expect = 1.7
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 835 FINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSETITQNFDGENIE 889
           F ++F     +E  T+ L  RV   P      P + WYRN  ++SPS+ +   + G+   
Sbjct: 319 FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDRAT 378

Query: 890 LVITNVDSEIDSGDY 904
           L  ++++ E D G Y
Sbjct: 379 LTFSHLNKE-DEGLY 392



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411
            +++R  N+ G  +     +VT+    LD P  PG+        +S+ + W+E ++     
Sbjct: 662  FRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDTSVVVTWEESKDA--KE 719

Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469
            ++ Y +E   + + +W    N  +  ++     L    +Y FR  AVN   +S+ S+ +E
Sbjct: 720  LVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRAVNAAGLSEYSQDSE 779

Query: 1470 YYKV 1473
              +V
Sbjct: 780  AIEV 783



 Score = 37.1 bits (82), Expect = 5.3
 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 2/43 (4%)

Query: 1963 ATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLLGYNI 2003
            A +   P +PL++  + +N   V+ SW  P  DGG+P+LGY I
Sbjct: 416  AEIAGAPASPLDVVCLDANKDYVIISWKQPAVDGGSPILGYFI 458


>UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin 2
            CG3665-PB, isoform B isoform 1; n=1; Apis mellifera|Rep:
            PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B
            isoform 1 - Apis mellifera
          Length = 741

 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 147/653 (22%), Positives = 253/653 (38%), Gaps = 69/653 (10%)

Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYE--REYR 1298
            +T +      +L      E    +YTC    A S    K   ++    I  D     +Y 
Sbjct: 68   YTELHQDNSLSLFFNSLQEQQAGKYTCKATYANSIQLQKSVTIDTIVAITWDNAPLNQYP 127

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358
            I  G D  +    +A P P+ +W+ N ++IK   H    ID+ +  L IK V+ +D G+Y
Sbjct: 128  IL-GEDFAIQCKVRARPSPSVDWLYNGELIKTNDHY--IIDTYA--LKIKNVQESDDGVY 182

Query: 1359 KLR--------LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410
              R        L+      +V +  T+ + P+P    N++E   +SI  C    +     
Sbjct: 183  TCRASVFSTGELKERPIRVEVHIRPTVSEMPNPI---NMIEGKDASIK-CEARGKPPPKF 238

Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470
            T +  +  +Q +   +  SV   T   T I N+  + +  ++  A N   ++  + T   
Sbjct: 239  TWVKSLT-HQNLSNVDRFSVDPDTGVLT-ITNVNRDDAGEYQCTATN---LAGTANTNIM 293

Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW--------YRDGKKL 1522
              VI + KI    +E    N T   +++  L C   G P P+VT+        Y  G +L
Sbjct: 294  VNVIVKPKI----IE--FLNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQL 347

Query: 1523 KTAKATYENRXXXXXXXXXXXXXXX-------YKCIAFNDHGEVETSCVVGIQQKPVI-T 1574
               +   EN                       Y+CIA N  G+      + ++  P   +
Sbjct: 348  DDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFAS 407

Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN-KLENDKEYNITTKEKTSVIRIK 1633
            +SN  +    +      ++ + E IP   + W   G+ K++NDK          S++ I 
Sbjct: 408  MSNTSVWSWDQKPVN--ISCIAESIPNATIRWTMYGDQKIDNDKMITQIGNGPRSILTIV 465

Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693
             L + + + Y   ASN  GT    + L+   KP +      M EI+  ++  +  PP   
Sbjct: 466  PLDKRYYTTYKCIASNAHGTRQRNIELREATKPGEML-QAKMAEITATTIRFDLVPPSTH 524

Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSE- 1751
                L    ++ ++ D   WI+  +    V++ Y ++ L     Y FR  A+N VG    
Sbjct: 525  PEQPLRTINVQ-YKEDGQTWIQARNKTWSVDSYYVLEGLKPQTMYEFRFAARNDVGLGNW 583

Query: 1752 -ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIIDYKV---EI 1806
             AL  E    +T  + P               + Y +TW     N G PI  Y++   +I
Sbjct: 584  GALHREMTPGRTVPNEPKIVMSREEYDMSRYSNQYELTWLAPADN-GEPIDMYQIKYCQI 642

Query: 1807 KQEGKKWKX-----XXXXXXXXARI----QKLSINTTYQFRIYARNEIGTSLP 1850
            ++   +W+               R+    + L  +T Y+  + A N IG S P
Sbjct: 643  RRVSGEWETLEDTCRTEDIRTQGRVRHWLRNLYSDTFYKVELKAHNAIGFSKP 695



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 82/331 (24%), Positives = 138/331 (41%), Gaps = 37/331 (11%)

Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694
           T+   P  QY   G D  ++C++ A P P + WL+ GE I  +++  +    D +     
Sbjct: 117 TWDNAPLNQYPILGEDFAIQCKVRARPSPSVDWLYNGELIKTNDHYII----DTY----A 168

Query: 695 LKITNVKKFQEGTYTV-VAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           LKI NV++  +G YT   +V   GE    PI +++       P V E    + + +G+  
Sbjct: 169 LKIKNVQESDDGVYTCRASVFSTGELKERPIRVEVHI----RPTVSEMPNPINMIEGKDA 224

Query: 753 ILSAQVVGNPRPTITWCKN--NKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAEN 809
            +  +  G P P  TW K+  ++ +  +   S D DT  +TI    +  D G Y   A N
Sbjct: 225 SIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGVLTITNVNR-DDAGEYQCTATN 283

Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW--- 866
             G A T+ ++ V        +P +    F   TV E     LV +    P P +T+   
Sbjct: 284 LAGTANTNIMVNV------IVKPKII--EFLNSTVVEDKEATLVCKAFGRPPPQVTFRKL 335

Query: 867 -----YRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
                Y     +     I +N   D E I  +  +     + G Y+C+A N+ G +    
Sbjct: 336 TAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIG 395

Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950
            +T++    +F      S  + + K V + C
Sbjct: 396 HLTVEFPP-SFASMSNTSVWSWDQKPVNISC 425



 Score = 71.3 bits (167), Expect = 3e-10
 Identities = 102/403 (25%), Positives = 163/403 (40%), Gaps = 61/403 (15%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G     +C+V   P P + W     +IK +     +Y  D  A L I+ V   D G +TC
Sbjct: 130 GEDFAIQCKVRARPSPSVDWLYNGELIKTND----HYIIDTYA-LKIKNVQESDDGVYTC 184

Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643
               A+ F  ST EL  E P+                       +   I PT S+ P   
Sbjct: 185 ---RASVF--STGEL-KERPIR----------------------VEVHIRPTVSEMPNPI 216

Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703
            + EG D  ++C     P P   W+    + +  +N+S      +     VL ITNV + 
Sbjct: 217 NMIEGKDASIKCEARGKPPPKFTWV----KSLTHQNLSNVDRFSVDPDTGVLTITNVNRD 272

Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             G Y   A N  G A+  I++ +       P++IE L S +V   E+ ++  +  G P 
Sbjct: 273 DAGEYQCTATNLAGTANTNIMVNVIV----KPKIIEFLNSTVVEDKEATLV-CKAFGRPP 327

Query: 764 PTITWCK---NNKPVKA--------LPTKSDGDTHSI-TILKPKKVK-DEGVYTLKAENS 810
           P +T+ K       VK         +   S  D+ +I T+   + ++ ++G+Y   A+N+
Sbjct: 328 PQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNA 387

Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
            G A     +TVE P    +     +  + +  V     I  +A    N     T Y  +
Sbjct: 388 GGDARRIGHLTVEFPPSFASMSNTSVWSWDQKPV----NISCIAESIPNATIRWTMY-GD 442

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913
           + I   + ITQ  +G    L I  +D    +  YKC+ASN+ G
Sbjct: 443 QKIDNDKMITQIGNGPRSILTIVPLDKRYYT-TYKCIASNAHG 484



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 100/469 (21%), Positives = 179/469 (38%), Gaps = 37/469 (7%)

Query: 1023 LQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081
            L  + +  +D AI + ++ +  +  V W  +GE+IK   + Y  +       L I+N   
Sbjct: 123  LNQYPILGEDFAI-QCKVRARPSPSVDWLYNGELIKTNDH-YIIDTYA----LKIKNVQE 176

Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEI-----ITRLQNQ-KVNKGNKATFEIELT-KGD 1134
             D+G Y+C     S T E+    +  E+     ++ + N   + +G  A+ + E   K  
Sbjct: 177  SDDGVYTCRASVFS-TGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPP 235

Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194
                W K  +    SN  + ++D     L I + + DDAGEY C   N   TA   +   
Sbjct: 236  PKFTWVKSLTHQNLSNVDRFSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANTNI-MV 294

Query: 1195 SINFTLRLPEFI--LVPANTDAYLTVEI----PDE------TLDVTWYKKKSVIEDTEKF 1242
            ++    ++ EF+   V  + +A L  +     P +      T +  + K   + +D    
Sbjct: 295  NVIVKPKIIEFLNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIIL 354

Query: 1243 TLISDVKKR--TLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYER-EYR 1298
                D  +   TL I +    +   Y C+  +A     ++    VEFPP           
Sbjct: 355  ENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFASMSNTSVW 414

Query: 1299 IKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357
                  V +    ++ P     W +   + I   K      +   + LTI  ++      
Sbjct: 415  SWDQKPVNISCIAESIPNATIRWTMYGDQKIDNDKMITQIGNGPRSILTIVPLDKRYYTT 474

Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417
            YK    N  G     + +    KP    +  + EI +++I      P       +    V
Sbjct: 475  YKCIASNAHGTRQRNIELREATKPGEMLQAKMAEITATTIRFDLVPPSTHPEQPLRTINV 534

Query: 1418 EYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISD 1463
            +Y+E D   WI  +N T +  S   ++ LK  + Y FR  A N+V + +
Sbjct: 535  QYKE-DGQTWIQARNKTWSVDSYYVLEGLKPQTMYEFRFAARNDVGLGN 582



 Score = 49.2 bits (112), Expect = 0.001
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 1/96 (1%)

Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558
           E+P   E  + P   E   P +  +G     +C+  G P P+ TW +       S +   
Sbjct: 196 ERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLS-NVDR 254

Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594
           +  D +   L I  V  +DAG + C A N AG A++
Sbjct: 255 FSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANT 290


>UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic
            acid-binding Ig-like lectin 1) (Siglec- 1) (CD169
            antigen).; n=3; Xenopus tropicalis|Rep: Sialoadhesin
            precursor (Sialic acid-binding Ig-like lectin 1) (Siglec-
            1) (CD169 antigen). - Xenopus tropicalis
          Length = 1483

 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 211/1096 (19%), Positives = 415/1096 (37%), Gaps = 137/1096 (12%)

Query: 633  PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
            PP   K        EG   ++ C + + P P +  L+K  +++   N   A    +++  
Sbjct: 276  PPRIPKFNSFLETQEGKLSIIHCSVDSNP-PSVLTLYKNGQVLATTNSHGAPTQRLNVIS 334

Query: 693  S----VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748
            S     L+I  V     G Y+ VA N  G ++  + L ++        VI P  S  + +
Sbjct: 335  SRNSLKLEIREVVMSDAGAYSCVATNAIGNSTACLRLTVEIARL----VISP--SSEIEE 388

Query: 749  GESVILSAQVVGNPRPTI--TWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTL 805
            G+ V L+     +    I  TW +N K +K        +T   T+  P+   +D G Y  
Sbjct: 389  GKEVTLTCFATRSSEKGIKYTWYRNGKWLK--------ETEEDTVTFPRVSSRDAGSYYC 440

Query: 806  KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865
             A++S+G + +S   T+       A   L ++ F   + +  G I  +  V  +P   + 
Sbjct: 441  LAQSSQG-SSSSPPRTLHVFF---APRDLSVSSFVGSSGRNLGII--LCTVDSDPHSELF 494

Query: 866  WYRNNEIISPSETITQN------FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919
             YR   +++ S  +  N          +++L I +V  E D G Y+C+A+N+ G      
Sbjct: 495  LYRKETLVASSTMLLHNRRYNISTSPNSLKLEIQDVFLE-DEGAYRCIANNTYGHMMGSL 553

Query: 920  RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979
              T++  K++ +   +         T IL   +       WY N           +  EG
Sbjct: 554  DFTMETAKISVIPTSEVHEAEAVNLTCILNSVSKGNFIYTWYKNS---------VLYSEG 604

Query: 980  RXXXXXXXXXXXXDVGVIKCIVKDQETS------TMLVVKETIPEFIRKLQDFEVKEKDV 1033
                         D G   C   +  TS       + V  E     ++   D EV +   
Sbjct: 605  PEPFLMFQRVSSSDSGSYYCRAWNNATSKSSSSCRLHVFYEPRSMQLKSYLDTEVGKSAF 664

Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR------KLYIRNTSVHDEGEY 1087
             +  V+       +++ +D E++  KKN  +  +R  +       ++ I++  + DEG+Y
Sbjct: 665  ILCTVDSYPPAQMLLYYQD-ELVISKKNLSNVNQRYRVSFSSNALRVDIQDVKLEDEGKY 723

Query: 1088 SCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD---ALVRWFK 1141
            +C   +   +   T+   V+L   ++T   + +V +  K     +LTK      +  W+K
Sbjct: 724  TCTSVNSVGSTNKTIYFKVQLARILVT--PSPEVKENEKVVLTCDLTKTQLEGTMYIWYK 781

Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201
            +   ++ S+   L  D  K          +D+G Y C+  +S+ + I       +++  R
Sbjct: 782  NSQRLRESSENTLVFDAVKS---------NDSGYYHCKAHSSQDSTISPSVSLHVSYAPR 832

Query: 1202 LP---EFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDT-------EKFTLISDVKK 1250
            +P    F    +     +   +  + L  ++ Y+ K ++  T       ++ T+ S    
Sbjct: 833  VPNMTSFWESHSGQVGIIECNVDSDPLSSLSLYRGKLLVGLTASSQTLNQRMTVSSSQNS 892

Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV--TLL 1308
              L+IR    +D+ EY C   ++   +   +       +I+      +++ G  V  T L
Sbjct: 893  LKLVIRDVVLEDEGEYVCTASNSIGHSTSAINFTAQTSRIL-ISPSSQVQEGMTVNLTCL 951

Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN-CG 1367
            V   A  +    W  N K     +H + S    S +L   +V + D G+Y   + ++   
Sbjct: 952  VASNAPGEVEYSWFQNGK-----EHPRGS----SKTLLFGRVSSEDGGLYYCTVRSDKVT 1002

Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427
             A   +N+ +   P      + +E  +  + I     ++   S ++  + E+Q +     
Sbjct: 1003 KASPTINLNVTYAPRNAYIKSFVETQNGEVAIIQCGVDSNPPSQLL-LLKEHQVV----- 1056

Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQSPTVE 1485
                  +   + + + + N  +      +   D+    E T  +  K +  TK  S  + 
Sbjct: 1057 -----ASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPTDEGTYIFTAKNVHGTKSVSSHLA 1111

Query: 1486 KPLKNITTEPN------EDIELTCIFGGVPQP--KVTWYRDGKKLKTAKATYENRXXXXX 1537
              +  I   P+      +   LTC     PQP    TWY++G+  +              
Sbjct: 1112 VEVARILVNPSPKLNEGQSATLTCNVLSTPQPVTSYTWYKNGRWFQEGFP-----GSLAF 1166

Query: 1538 XXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596
                      Y C     +G        + +Q  P   +    ++   K  D+ ++   +
Sbjct: 1167 EKVLSADAGTYACTGHTANGTWPSLPITLYVQYAPKNLLVTSFLEPHGK--DQGIILCKL 1224

Query: 1597 EGIPPPEVIWYKNGNKL------ENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEAS 1648
            + +PP  +  ++ G  L      + D+     +    + +R  I+++    S +Y   A+
Sbjct: 1225 DSVPPSVITLHREGTVLASTMPAQPDQGQKFWSFSSHNYLRLEIRDVTAEDSGRYVCTAN 1284

Query: 1649 NTAG--TSSVEVTLKV 1662
            NT G  TSSV  T+ V
Sbjct: 1285 NTIGSTTSSVLFTINV 1300



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 192/979 (19%), Positives = 369/979 (37%), Gaps = 129/979 (13%)

Query: 746  VRQGESVILSAQVVGNPRPTI--TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803
            VR+GE+V L+  V G     I  +W KN+  +K      DG T S+ IL      D G Y
Sbjct: 201  VREGEAVTLTCDVPGADPDQIHYSWYKNSLWIK------DGATRSL-ILYEAAASDAGYY 253

Query: 804  TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVP 862
            + K +N +G   +  VI           PP  I +F      ++G + ++   V  NP  
Sbjct: 254  SCKVQNDKGSDSSPPVIL------HVLYPPR-IPKFNSFLETQEGKLSIIHCSVDSNPPS 306

Query: 863  SITWYRNNEIIS-------PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915
             +T Y+N ++++       P++ +       +++L I  V    D+G Y CVA+N+ G S
Sbjct: 307  VLTLYKNGQVLATTNSHGAPTQRLNVISSRNSLKLEIREVVMS-DAGAYSCVATNAIGNS 365

Query: 916  SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT----VSTKWYHNKKEISGMD 971
            +   R+T+++ ++     +  S E EEGK V L C  + +    +   WY N K      
Sbjct: 366  TACLRLTVEIARLV----ISPSSEIEEGKEVTLTCFATRSSEKGIKYTWYRNGK------ 415

Query: 972  HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE- 1030
                ++E              D G   C+ +  + S+    + T+  F    +D  V   
Sbjct: 416  ---WLKETEEDTVTFPRVSSRDAGSYYCLAQSSQGSSSSPPR-TLHVFFAP-RDLSVSSF 470

Query: 1031 -----KDVAILEVEINSET-ADVVWERDGEIIKPK-----KNKYDFEKRGHIRKLYIRNT 1079
                 +++ I+   ++S+  +++   R   ++          +Y+     +  KL I++ 
Sbjct: 471  VGSSGRNLGIILCTVDSDPHSELFLYRKETLVASSTMLLHNRRYNISTSPNSLKLEIQDV 530

Query: 1080 SVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135
             + DEG Y CI  +       + + T+      +I   +  +    N       ++KG+ 
Sbjct: 531  FLEDEGAYRCIANNTYGHMMGSLDFTMETAKISVIPTSEVHEAEAVNLTCILNSVSKGNF 590

Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAI 1188
            +  W+K  + + +S       +G +  L        D+G Y C   N       S C   
Sbjct: 591  IYTWYK--NSVLYS-------EGPEPFLMFQRVSSSDSGSYYCRAWNNATSKSSSSCRLH 641

Query: 1189 LTVEEPSINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244
            +  E  S+     L   +     +    D+Y   ++     D     KK++    +++ +
Sbjct: 642  VFYEPRSMQLKSYLDTEVGKSAFILCTVDSYPPAQMLLYYQDELVISKKNLSNVNQRYRV 701

Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303
                    + I+    +D+ +YTC  +++  ST K     V+    +V    E  +K   
Sbjct: 702  SFSSNALRVDIQDVKLEDEGKYTCTSVNSVGSTNKTIYFKVQLARILVTPSPE--VKENE 759

Query: 1304 DVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361
             V L  D            W  NS+ ++         +S   +L    V++ D+G Y  +
Sbjct: 760  KVVLTCDLTKTQLEGTMYIWYKNSQRLR---------ESSENTLVFDAVKSNDSGYYHCK 810

Query: 1362 LENNCGHA-DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420
              ++        +++ +   P  P   +  E  S  + I     ++   S++  Y  +  
Sbjct: 811  AHSSQDSTISPSVSLHVSYAPRVPNMTSFWESHSGQVGIIECNVDSDPLSSLSLYRGK-- 868

Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE--TTEYYKVIKETK 1478
                   + V     +QT  Q +  +SS       + +V + D  E   T    +   T 
Sbjct: 869  -------LLVGLTASSQTLNQRMTVSSSQNSLKLVIRDVVLEDEGEYVCTASNSIGHSTS 921

Query: 1479 IQSPTVE--KPLKNITTEPNE--DIELTC-IFGGVP-QPKVTWYRDGKKLKTAKATYENR 1532
              + T +  + L + +++  E   + LTC +    P + + +W+++GK+     +     
Sbjct: 922  AINFTAQTSRILISPSSQVQEGMTVNLTCLVASNAPGEVEYSWFQNGKEHPRGSS----- 976

Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEW 1590
                           Y C   +D     T     I         N  IK   + + G+  
Sbjct: 977  KTLLFGRVSSEDGGLYYCTVRSDK---VTKASPTINLNVTYAPRNAYIKSFVETQNGEVA 1033

Query: 1591 LVTAVIEGIPPPEVIWYKN-------GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643
            ++   ++  PP +++  K        G+   + + +N      T  + IK+L  +    Y
Sbjct: 1034 IIQCGVDSNPPSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPTDEGTY 1093

Query: 1644 TIEASNTAGTSSVEVTLKV 1662
               A N  GT SV   L V
Sbjct: 1094 IFTAKNVHGTKSVSSHLAV 1112



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 103/483 (21%), Positives = 189/483 (39%), Gaps = 62/483 (12%)

Query: 648  GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV----LKITNVKKF 703
            G   +++C + + P P    L K  ++V     S       + Y S     L+I ++   
Sbjct: 1030 GEVAIIQCGVDSNP-PSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPT 1088

Query: 704  QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763
             EGTY   A N  G  S+   L ++        ++ P  S  + +G+S  L+  V+  P+
Sbjct: 1089 DEGTYIFTAKNVHGTKSVSSHLAVEVARI----LVNP--SPKLNEGQSATLTCNVLSTPQ 1142

Query: 764  P--TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821
            P  + TW KN +  +      +G   S+   K     D G Y      + G   +  +  
Sbjct: 1143 PVTSYTWYKNGRWFQ------EGFPGSLAFEKVLSA-DAGTYACTGHTANGTWPSLPITL 1195

Query: 822  VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881
              +   +N    L +  F E   K++G I  + ++   P   IT +R   +++ +     
Sbjct: 1196 YVQYAPKN----LLVTSFLEPHGKDQGII--LCKLDSVPPSVITLHREGTVLASTMPAQP 1249

Query: 882  N-------FDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933
            +       F   N + L I +V +E DSG Y C A+N+ G ++     TI+V ++     
Sbjct: 1250 DQGQKFWSFSSHNYLRLEIRDVTAE-DSGRYVCTANNTIGSTTSSVLFTINVARIL---- 1304

Query: 934  LQKSYETEEGKTVILECQTSHT----VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989
            +  S E +E + V+L C  + T        WY N +          ++E           
Sbjct: 1305 VTPSPEVKENEKVVLTCDLTKTQLEGTMYIWYKNSQR---------LRESSENTLVFDAV 1355

Query: 990  XXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDF-EVKEKDVAILEVEINSE-T 1044
               D G   C     + ST+   + +  + P     L  F E + K   ++   + S+  
Sbjct: 1356 KSNDSGYYHCKAHSSQDSTISPSVSLHVSYPPRNLSLSSFLEAQGKRQGVISCRVESDPP 1415

Query: 1045 ADVVWERDGEI----IKPKKNKYDFEKRGH-IRKLYIRNTSVHDEGEYSCILRDESCTAE 1099
            + +V  + G++    +    NK       H   +L +   +  D+GEY+C   +    A+
Sbjct: 1416 SQLVLYKGGQVAASFVPQSTNKRVRLSSSHNALRLEMEEVAPEDQGEYTCQATNSLGAAQ 1475

Query: 1100 VTV 1102
             +V
Sbjct: 1476 TSV 1478



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 75/346 (21%), Positives = 128/346 (36%), Gaps = 58/346 (16%)

Query: 861  VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920
            V   TWYRNN++ S    +  +F        IT      D GD++C   N  G  +    
Sbjct: 137  VSGYTWYRNNKVFSREPIV--SFPS------ITRQ----DFGDFRCEVQNPEGTGTSEVS 184

Query: 921  VTIDVEKVTFVKHLQKSYETEEGKTVILECQT----SHTVSTKWYHNKKEISGMDHREII 976
              I     T V     S E  EG+ V L C         +   WY N            I
Sbjct: 185  RLIVFSANTLV---SPSSEVREGEAVTLTCDVPGADPDQIHYSWYKNSL---------WI 232

Query: 977  QEGRXXXXXXXXXXXXDVGVIKCIV---KDQETSTMLVVKETIPEFIRKLQDF-EVKEKD 1032
            ++G             D G   C V   K  ++S  +++    P  I K   F E +E  
Sbjct: 233  KDGATRSLILYEAAASDAGYYSCKVQNDKGSDSSPPVILHVLYPPRIPKFNSFLETQEGK 292

Query: 1033 VAILEVEINSETADVV-WERDGEII-------KPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084
            ++I+   ++S    V+   ++G+++        P +       R  + KL IR   + D 
Sbjct: 293  LSIIHCSVDSNPPSVLTLYKNGQVLATTNSHGAPTQRLNVISSRNSL-KLEIREVVMSDA 351

Query: 1085 GEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKAT---FEIELTKGDALVR 1138
            G YSC+  +    S       VE+   +I+   + ++ +G + T   F    ++      
Sbjct: 352  GAYSCVATNAIGNSTACLRLTVEIARLVIS--PSSEIEEGKEVTLTCFATRSSEKGIKYT 409

Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184
            W+++G  ++ +    +T      +         DAG Y C   +S+
Sbjct: 410  WYRNGKWLKETEEDTVTFPRVSSR---------DAGSYYCLAQSSQ 446



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 8/88 (9%)

Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIK-------PSQDFQMYYDDDNVATLVIREV 573
           T +G      C V+  P   +T ++   ++        P+Q   +     N   L IREV
Sbjct: 288 TQEGKLSIIHCSVDSNPPSVLTLYKNGQVLATTNSHGAPTQRLNVI-SSRNSLKLEIREV 346

Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601
              DAG ++CVA NA G +++   L VE
Sbjct: 347 VMSDAGAYSCVATNAIGNSTACLRLTVE 374



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 6/87 (6%)

Query: 521  TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY------YDDDNVATLVIREVF 574
            T +G     +C V+  P  Q+   ++  ++    D  ++      Y   N   L I+++ 
Sbjct: 1027 TQNGEVAIIQCGVDSNPPSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLM 1086

Query: 575  PEDAGTFTCVAKNAAGFASSTTELIVE 601
            P D GT+   AKN  G  S ++ L VE
Sbjct: 1087 PTDEGTYIFTAKNVHGTKSVSSHLAVE 1113


>UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whole
            genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14681, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 862

 Score = 89.0 bits (211), Expect = 1e-15
 Identities = 85/332 (25%), Positives = 137/332 (41%), Gaps = 22/332 (6%)

Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651
            +T V  G P P V W      L  + +  I      +V+ + ++++S  + YT  A +T 
Sbjct: 339  ITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR----NVLELTDVRQS--ANYTCVAMSTL 392

Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711
            G       + V   P  P  PV+  E +  S+T+ W    D G  E   Y I +H+   +
Sbjct: 393  GVIEAMAQITVKALPKAPGTPVVT-ERTATSITLTW----DSGNPEPVSYYIIQHKSKYS 447

Query: 1712 RWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770
              +   ++D    T Y +  L+   +Y FRV+A N +G      SE I  KTA   PS  
Sbjct: 448  DDL-YKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIG--RGPPSEIIEAKTAEQAPSTA 504

Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827
                    + + +  I W   E+  G  +   + Y ++  Q    W+           IQ
Sbjct: 505  PRQVRGHMMSSTTAVIHWDEPEEANGQIMGYRVYYTMDSSQHVNLWEKQIVRGSKFVTIQ 564

Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887
             L  N TY  ++ A   +G   P + D +I I KT  P SQP +F     +  S+ L W 
Sbjct: 565  GLIPNKTYYIKVLAYTSVGDG-PLSPDLQI-ITKTGVP-SQPTDFKAEAKSETSILLSWI 621

Query: 1888 EPESNG-GSPITNYIIEFKTVKGKSWTKIVTV 1918
             P   G  + IT Y + ++        +I+ +
Sbjct: 622  APAQTGQENQITGYELVYRKSDDTEEVRILAI 653



 Score = 66.5 bits (155), Expect = 8e-09
 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 15/189 (7%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSIT 790
           PP+ +         QG       Q  G+PRP I W K  K V +      + D  + S+ 
Sbjct: 67  PPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVSSQRFEVIEFDDGSGSVL 126

Query: 791 ILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF--INRFQEITVKEK 847
            ++P +  +DE +Y   A NS G    +  +TV     E+  PP F  I+   ++ V E+
Sbjct: 127 RIQPLRTPRDEAIYECVASNSVGETSATTRLTV---LREDQLPPGFPTIDMGPQLKVVER 183

Query: 848 G-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS--EIDSGDY 904
             T  ++   + NP P I+W+++     P  T T N   + +      ++   E D G Y
Sbjct: 184 TRTATMLCAASGNPDPDISWFKD---FLPVNTTTNNGRIKQLRSGALQIEQSEESDQGKY 240

Query: 905 KCVASNSAG 913
           +CVA+N+ G
Sbjct: 241 ECVATNNDG 249



 Score = 59.3 bits (137), Expect = 1e-06
 Identities = 63/247 (25%), Positives = 99/247 (40%), Gaps = 32/247 (12%)

Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY-Y 560
           T  +    P F+     +    G    F CQ  G PRP+I W ++   +  SQ F++  +
Sbjct: 60  TPVDSGAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVS-SQRFEVIEF 118

Query: 561 DDDNVATLVIREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619
           DD + + L I+ +  P D   + CVA N+ G  S+TT L V                   
Sbjct: 119 DDGSGSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTV------------------- 159

Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679
                  D L    PT    P+ + V+      + C     P+PDI+W FK  + +P  N
Sbjct: 160 ----LREDQLPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISW-FK--DFLP-VN 211

Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVI 738
            +        +    L+I   ++  +G Y  VA N +G   S P  L ++ G K  P   
Sbjct: 212 TTTNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVR-GRKLAPAAF 270

Query: 739 EPLKSMI 745
             L + +
Sbjct: 271 ARLSNTL 277



 Score = 57.2 bits (132), Expect = 5e-06
 Identities = 55/191 (28%), Positives = 83/191 (43%), Gaps = 15/191 (7%)

Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           G PP F + P  Q   +G      C+    P P I W  KG++ V  +   V IE D   
Sbjct: 65  GAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKK-VSSQRFEV-IEFD-DG 121

Query: 691 YCSVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMI 745
             SVL+I  ++    E  Y  VA N  GE S    L +   ++ PP      + P   ++
Sbjct: 122 SGSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTVLREDQLPPGFPTIDMGPQLKVV 181

Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEG 801
            R   + +L A   GNP P I+W K+  PV    T ++G    +      ++  +  D+G
Sbjct: 182 ERTRTATMLCA-ASGNPDPDISWFKDFLPVNT--TTNNGRIKQLRSGALQIEQSEESDQG 238

Query: 802 VYTLKAENSEG 812
            Y   A N++G
Sbjct: 239 KYECVATNNDG 249



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 12/185 (6%)

Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346
            PP+      +  I  G  V +       P P  +W++ ++ +       P  D       
Sbjct: 319  PPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNV 372

Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406
            ++  +   +  Y     +  G  +    +T+   P  PG P + E  ++SI + WD    
Sbjct: 373  LELTDVRQSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTWD---- 428

Query: 1407 TGN-STIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464
            +GN   + YY+++++   + + +  +  +  T+ S+  L   S Y FR  A+N +     
Sbjct: 429  SGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPP 488

Query: 1465 SETTE 1469
            SE  E
Sbjct: 489  SEIIE 493



 Score = 51.2 bits (117), Expect = 3e-04
 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GE 886
           ++  PP F+    + T  + G    V + T +P P I W +  + +S        FD G 
Sbjct: 63  DSGAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVSSQRFEVIEFDDGS 122

Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
              L I  + +  D   Y+CVASNS G++S   R+T+
Sbjct: 123 GSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTV 159



 Score = 46.8 bits (106), Expect = 0.007
 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 20/135 (14%)

Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691
           +PP FS  P    +  G  + + C  V  P P + W+   E++ P        E DM + 
Sbjct: 318 VPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIG 369

Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749
            +VL++T+V+  Q   YT VA++  G       + +K   K P  P V E   + I    
Sbjct: 370 RNVLELTDVR--QSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTW 427

Query: 750 ESVILSAQVVGNPRP 764
           +S        GNP P
Sbjct: 428 DS--------GNPEP 434



 Score = 37.9 bits (84), Expect = 3.0
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSK-YTIEASNTAGTSS 1655
            G P P+++W K G K+ + +   I   + + SV+RI+ L+       Y   ASN+ G +S
Sbjct: 93   GDPRPKIVWNKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGETS 152

Query: 1656 VEVTLKVYDKPSKPEG 1671
                L V  +   P G
Sbjct: 153  ATTRLTVLREDQLPPG 168


>UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin -
           Homo sapiens (Human)
          Length = 498

 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 55/206 (26%), Positives = 94/206 (45%), Gaps = 8/206 (3%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           PP F + P+   +DEG    ++ ++  +P PD++W   G  +  D+ +   I S+  ++ 
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD-LHKMIVSEKGLHS 307

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGES 751
            + ++  V+    G Y  VA NR GEA+  + L +   E K  P  I   +S  V +G+S
Sbjct: 308 LIFEV--VRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365

Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807
           V L  Q+   P P + W +NN+ V+     +    D       ++K    KD G YT+ A
Sbjct: 366 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 425

Query: 808 ENSEGIAETSAVITVEEPTEENAEPP 833
            N  G+   +  + V     +    P
Sbjct: 426 VNEAGVTTCNTRLDVTARPNQTLPAP 451



 Score = 77.0 bits (181), Expect = 5e-12
 Identities = 65/251 (25%), Positives = 108/251 (43%), Gaps = 30/251 (11%)

Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556
           V ++   +E+   P F++        +G   + + +V G P P ++W+     ++     
Sbjct: 237 VNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLH 296

Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXX 616
           +M   +  + +L+   V   DAG + CVAKN AG A+ T +L V A   +H         
Sbjct: 297 KMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA--KEHKR------- 347

Query: 617 XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP 676
                            P F  KP+++ V EG  + LEC++ AIP P + W  +  E+V 
Sbjct: 348 ----------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK-RNNEMVQ 390

Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736
                +++  D     ++L I +V K   G YTV AVN  G  +    L +      P Q
Sbjct: 391 FNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA---RPNQ 446

Query: 737 VIEPLKSMIVR 747
            +   K + VR
Sbjct: 447 TLPAPKQLRVR 457



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 52/196 (26%), Positives = 99/196 (50%), Gaps = 10/196 (5%)

Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSI 789
           PP+ I+  ++M + +G    +  +V G P P ++W  N + V++        S+   HS+
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849
            I +  +  D G Y   A+N  G  E +  + ++   +E+   P+FI + Q   V E  +
Sbjct: 309 -IFEVVRASDAGAYACVAKNRAG--EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365

Query: 850 IKLVARVTRNPVPSITWYRNNEIIS-PSETITQNFDGE-NIELVITNVDSEIDSGDYKCV 907
           +KL  +++  P P + W RNNE++   ++ I+   D    + L+I +V+ + D+G Y   
Sbjct: 366 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKK-DAGWYTVS 424

Query: 908 ASNSAGKSSHGARVTI 923
           A N AG ++   R+ +
Sbjct: 425 AVNEAGVTTCNTRLDV 440



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%)

Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882
           ++  +E   PP FI   + +++ E    ++  +V+  P P ++WY N   +   +     
Sbjct: 240 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 299

Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTFVKHLQKSYE 939
              + +  +I  V    D+G Y CVA N AG+++   ++ +   + ++     +  +S +
Sbjct: 300 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK 359

Query: 940 TEEGKTVILECQTSHTVSTK--WYHNKKEI 967
             EG +V LECQ S     K  W  N + +
Sbjct: 360 VLEGDSVKLECQISAIPPPKLFWKRNNEMV 389



 Score = 54.0 bits (124), Expect = 4e-05
 Identities = 40/203 (19%), Positives = 83/203 (40%), Gaps = 10/203 (4%)

Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYE 1530
            + K   P   +  +N++ +      +     G+P P V+WY +G+ +++        + +
Sbjct: 244  QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 303

Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVG 1587
                             Y C+A N  GE   +    V+  + K       +   +K   G
Sbjct: 304  GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEG 363

Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTI 1645
            D   +   I  IPPP++ W +N   ++ + +     ++ T    + IK++ +  +  YT+
Sbjct: 364  DSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 423

Query: 1646 EASNTAGTSSVEVTLKVYDKPSK 1668
             A N AG ++    L V  +P++
Sbjct: 424  SAVNEAGVTTCNTRLDVTARPNQ 446



 Score = 39.1 bits (87), Expect = 1.3
 Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 1/96 (1%)

Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-S 1344
            +PP+ +       I  G    +       P P+  W +N + ++     K  +  K   S
Sbjct: 248  YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307

Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380
            L  + V  +DAG Y    +N  G A   + + +L K
Sbjct: 308  LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343



 Score = 38.3 bits (85), Expect = 2.3
 Identities = 42/209 (20%), Positives = 90/209 (43%), Gaps = 14/209 (6%)

Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164
            PP  I   +N  +++G     + +++   A  V W+ +G  +Q  +  ++ +  K     
Sbjct: 249  PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308

Query: 1165 IYDC-DLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAY----LTV 1218
            I++     DAG Y+C   N    A  TV+ +       R P FI  P +        + +
Sbjct: 309  IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368

Query: 1219 EIPDETL---DVTWYKKKSVIE-DTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLD- 1272
            E     +    + W +   +++ +T++ +L  D   R TL+I+   + D   YT   ++ 
Sbjct: 369  ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428

Query: 1273 -AKSTTKLKVEVVEFPPKIVDYEREYRIK 1300
               +T   +++V   P + +   ++ R++
Sbjct: 429  AGVTTCNTRLDVTARPNQTLPAPKQLRVR 457


>UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5;
            Vertebrata|Rep: Neogenin/DCC long isoform - Petromyzon
            marinus (Sea lamprey)
          Length = 1415

 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 116/521 (22%), Positives = 203/521 (38%), Gaps = 40/521 (7%)

Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520
            I   +ET   Y   K T ++ P +    +N     ++DI L C   G P+P ++W+++G 
Sbjct: 312  IKAQNETQRLYA--KLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGD 369

Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN--DHGEVETSCVVGIQQKPVITISNE 1578
             +                         Y+C+A +  D  +     VV     P I  S+ 
Sbjct: 370  LIIPDDFIQIVDGSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSP 429

Query: 1579 D------IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632
                   +     +   W   A   G      ++Y     +   +   +   E   V+  
Sbjct: 430  PRGMTAVLVSTRFIRLSWRAPAESRGSVLHYSVYYVRVGSVRERRVDTLQVSELQLVVG- 488

Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPVI---MREISRESVTIEWK 1688
             EL+      + + A N AG       L++  +P  +  GPV+   +  IS  SV+++W 
Sbjct: 489  -ELRPETGYSFQVVAVNQAGPGERSAPLRITTQPEVQVPGPVLNLHVVAISTTSVSLQWD 547

Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748
            PP +     +  Y +   + D     +  D D D  ++  + L +   Y FRV+A N  G
Sbjct: 548  PPANVFS-PIMHYKLYYMQLDGEATTE-HDQDTDGPSFTKEGLRKFTRYSFRVVAYNKHG 605

Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS--EKNGGSPIIDYKVEI 1806
                + SE  +++T  DVPS          ++++SV + W P   E + G  I  YK   
Sbjct: 606  --PGVSSEDTIVRTYSDVPSGSPQELILEVVNSQSVLVRWKPPLLETHNGD-ITGYK--- 659

Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSI----NTTYQFRIYARNEIGTSLPYTS-DDKITIGK 1861
            + EGK  +         A +  L++     + Y FR+ A N  GT  P++      T   
Sbjct: 660  RHEGKAGRRAEAEIEETAHLSYLAVGLDRGSEYSFRVAAVNSNGTG-PFSDWLSSETFQA 718

Query: 1862 TLTP---PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918
             L     P QP +  V    + S+ + WT P +N    +  Y + +    G    K + V
Sbjct: 719  DLDESRVPDQPSSLHVRPFPT-SIVVSWT-PPANPQIMVRGYALGYGI--GSPHGKSLRV 774

Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVR 1958
                  + I+N++   + +  + A N +G  +P  ES + R
Sbjct: 775  DSKQRYYTIDNLEPSSQYVISLKAFNHMGEGIPLYESATTR 815



 Score = 85.8 bits (203), Expect = 1e-14
 Identities = 123/570 (21%), Positives = 217/570 (38%), Gaps = 39/570 (6%)

Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560
            L C+  G P P V W R  + + + + +                   Y CI    +    
Sbjct: 261  LECVVAGFPAPSVHWTRGTESVLSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQNETQR 320

Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620
                + + + P I    E+  +   V D+ ++    EG P P + W++NG+ +  D    
Sbjct: 321  LYAKLTVLEPPRILHGPEN--RNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQ 378

Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK------PSKPEGPVI 1674
            I        + I  +  S    Y   A +          L V +        S P   + 
Sbjct: 379  IV----DGSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSPPRGMT 434

Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734
               +S   + + W+ P +  G  +  Y++      + R  +V  +        + +L   
Sbjct: 435  AVLVSTRFIRLSWRAPAESRG-SVLHYSVYYVRVGSVRERRVDTLQVSELQLVVGELRPE 493

Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794
              Y F+V+A N  G  E      I  +  + VP           I   SV + W P   N
Sbjct: 494  TGYSFQVVAVNQAGPGERSAPLRITTQPEVQVPG-PVLNLHVVAISTTSVSLQWDP-PAN 551

Query: 1795 GGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPYT 1852
              SPI+ YK+   Q   +               K  +   T Y FR+ A N+ G  +  +
Sbjct: 552  VFSPIMHYKLYYMQLDGEATTEHDQDTDGPSFTKEGLRKFTRYSFRVVAYNKHGPGV--S 609

Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEFKTVKGK 1910
            S+D I    +  P   P+  ++    S+SV ++W  P  E++ G  IT Y    K  +GK
Sbjct: 610  SEDTIVRTYSDVPSGSPQELILEVVNSQSVLVRWKPPLLETHNGD-ITGY----KRHEGK 664

Query: 1911 SWTKI-VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS-----LPTESQSVRLEKHA 1963
            +  +    +  + H  +    +    E  FR++A N+ G       L +E+    L++ +
Sbjct: 665  AGRRAEAEIEETAHLSYLAVGLDRGSEYSFRVAAVNSNGTGPFSDWLSSETFQADLDE-S 723

Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023
             VP  P++ L +R   ++IV+ SW TP  +    + GY +    +       + +VD   
Sbjct: 724  RVPDQPSS-LHVRPFPTSIVV-SW-TPPANPQIMVRGYALGY-GIGSPHGKSL-RVDSKQ 778

Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053
              + I +L  +  Y+I + A N +G   PL
Sbjct: 779  RYYTIDNLEPSSQYVISLKAFNHMGEGIPL 808



 Score = 66.9 bits (156), Expect = 6e-09
 Identities = 79/368 (21%), Positives = 150/368 (40%), Gaps = 39/368 (10%)

Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG------NSKCTAILT 1190
            VRWFK+G  I   + + +   G    L + +    D G+Y C++        ++ T +  
Sbjct: 176  VRWFKEGRSITEDSQVMVLSSGD---LLLQNASKADGGKYFCQLVFGGRTFTNQGTNLSV 232

Query: 1191 VEEPSIN---FTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYK-KKSVIEDTEKFTLI 1245
            + E   N     LR P  + V     A L   +       V W +  +SV+  +E+F+++
Sbjct: 233  LPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVL--SERFSVV 290

Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGS 1303
            +      L I    +DD  +YTC++     T +L  K+ V+E PP+I+            
Sbjct: 291  AG---GILRIDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLE-PPRILHGPENRNASVSD 346

Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363
            D+ L    +  P+P   W  N  +I         I     SL I  V  +D G+Y+   E
Sbjct: 347  DIILECQAEGRPRPVISWFQNGDLI----IPDDFIQIVDGSLHILGVMASDEGVYQCMAE 402

Query: 1364 NNCGHADVEMNVTILD-------KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416
            +          + +++         SPP     + + +  I + W  P  +  S +++Y 
Sbjct: 403  SEVDGMQAAAQLVVINHAVPGILASSPPRGMTAVLVSTRFIRLSWRAPAESRGS-VLHYS 461

Query: 1417 VEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474
            V Y  + +     +    +++ Q  +  L+  + Y F+  AVN+   +   E +   ++ 
Sbjct: 462  VYYVRVGSVRERRVDTLQVSELQLVVGELRPETGYSFQVVAVNQ---AGPGERSAPLRIT 518

Query: 1475 KETKIQSP 1482
             + ++Q P
Sbjct: 519  TQPEVQVP 526



 Score = 61.3 bits (142), Expect = 3e-07
 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 18/177 (10%)

Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707
           G    LEC +   P P + W  +G E V  E  SV           +L+I NV++   G 
Sbjct: 256 GHTATLECVVAGFPAPSVHWT-RGTESVLSERFSVVAGG-------ILRIDNVQQDDAGD 307

Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767
           YT + +  + E      L  K    EPP+++   ++      + +IL  Q  G PRP I+
Sbjct: 308 YTCI-IKAQNETQR---LYAKLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVIS 363

Query: 768 WCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822
           W +N   +         DG  H + ++      DEGVY   AE+     + +A + V
Sbjct: 364 WFQNGDLIIPDDFIQIVDGSLHILGVM----ASDEGVYQCMAESEVDGMQAAAQLVV 416



 Score = 57.6 bits (133), Expect = 4e-06
 Identities = 67/293 (22%), Positives = 119/293 (40%), Gaps = 23/293 (7%)

Query: 634 PTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692
           P F     +  V +G  ++L+C   V     ++ W  +G  I  D  + V    D+ +  
Sbjct: 144 PRFVSSSLSTLVIQGDSVVLDCGAEVTGLWNEVRWFKEGRSITEDSQVMVLSSGDLLLQ- 202

Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752
           +  K    K F +  +       +G  +L ++ ++++    P  V+     + VR G + 
Sbjct: 203 NASKADGGKYFCQLVFGGRTFTNQG-TNLSVLPEMESNR--PCVVLRHPVDVSVRLGHTA 259

Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT--LKAENS 810
            L   V G P P++ W +  + V  L  +       I  +   +  D G YT  +KA+N 
Sbjct: 260 TLECVVAGFPAPSVHWTRGTESV--LSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQNE 317

Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870
                  A +TV        EPP  ++  +         I L  +    P P I+W++N 
Sbjct: 318 T--QRLYAKLTV-------LEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNG 368

Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923
           ++I P + I Q  DG    L I  V +  D G Y+C+A +        A++ +
Sbjct: 369 DLIIPDDFI-QIVDG---SLHILGVMAS-DEGVYQCMAESEVDGMQAAAQLVV 416



 Score = 46.0 bits (104), Expect = 0.011
 Identities = 75/303 (24%), Positives = 124/303 (40%), Gaps = 36/303 (11%)

Query: 897  SEIDSGDYKC-VASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954
            + IDSG Y+C V  +  G   S  A VT+ + +  FV     S    +G +V+L+C    
Sbjct: 112  ARIDSGRYQCEVTVHGLGSIISRPAAVTL-IGEPRFVSS-SLSTLVIQGDSVVLDCGAEV 169

Query: 955  TV---STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTML 1010
            T      +W+   + I+      ++  G             D G   C +V    T T  
Sbjct: 170  TGLWNEVRWFKEGRSITEDSQVMVLSSG---DLLLQNASKADGGKYFCQLVFGGRTFTNQ 226

Query: 1011 VVK-ETIPEF--------IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKK 1060
                  +PE         +R   D  V+    A LE  +    A  V W R  E +  ++
Sbjct: 227  GTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSER 286

Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT----AEVTVVELPPEIITRLQNQ 1116
              +     G +R   I N    D G+Y+CI++ ++ T    A++TV+E PP I+   +N+
Sbjct: 287  --FSVVAGGILR---IDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLE-PPRILHGPENR 340

Query: 1117 KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175
              +  +    E +   +   ++ WF++G  I   + IQ+ +DG    L I      D G 
Sbjct: 341  NASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQI-VDG---SLHILGVMASDEGV 396

Query: 1176 YSC 1178
            Y C
Sbjct: 397  YQC 399



 Score = 44.8 bits (101), Expect = 0.026
 Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 5/71 (7%)

Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589
           ECQ EG PRP I+WF+   +I P  DF    D     +L I  V   D G + C+A++  
Sbjct: 351 ECQAEGRPRPVISWFQNGDLIIP-DDFIQIVD----GSLHILGVMASDEGVYQCMAESEV 405

Query: 590 GFASSTTELIV 600
               +  +L+V
Sbjct: 406 DGMQAAAQLVV 416



 Score = 42.7 bits (96), Expect = 0.11
 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 1/58 (1%)

Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690
           PP     P+ +      DI+LEC+    P P I+W   G+ I+PD+ I + ++  +H+
Sbjct: 330 PPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQI-VDGSLHI 386



 Score = 39.5 bits (88), Expect = 0.99
 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583
           G T   EC V G+P P + W R T  +  S+ F +         L I  V  +DAG +TC
Sbjct: 256 GHTATLECVVAGFPAPSVHWTRGTESVL-SERFSVVAG----GILRIDNVQQDDAGDYTC 310

Query: 584 VAKNAAGFASSTTEL-IVEAPLSDHGSE 610
           + K          +L ++E P   HG E
Sbjct: 311 IIKAQNETQRLYAKLTVLEPPRILHGPE 338



 Score = 36.7 bits (81), Expect = 7.0
 Identities = 49/240 (20%), Positives = 87/240 (36%), Gaps = 20/240 (8%)

Query: 864  ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVT 922
            + W++    I+    +     G+   L++ N  S+ D G Y C +       ++ G  ++
Sbjct: 176  VRWFKEGRSITEDSQVMVLSSGD---LLLQNA-SKADGGKYFCQLVFGGRTFTNQGTNLS 231

Query: 923  I----DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE 978
            +    +  +   V           G T  LEC  +   +   +  +   S +  R  +  
Sbjct: 232  VLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSERFSVVA 291

Query: 979  GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAI 1035
            G             D G   CI+K Q  +  L  K T+   P  +   ++      D  I
Sbjct: 292  G--GILRIDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLEPPRILHGPENRNASVSDDII 349

Query: 1036 LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094
            LE +       V+ W ++G++I P     DF +      L+I      DEG Y C+   E
Sbjct: 350  LECQAEGRPRPVISWFQNGDLIIPD----DFIQIVD-GSLHILGVMASDEGVYQCMAESE 404


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.312    0.131    0.377 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 2,321,944,652
Number of Sequences: 1657284
Number of extensions: 99355269
Number of successful extensions: 284776
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 690
Number of HSP's successfully gapped in prelim test: 1169
Number of HSP's that attempted gapping in prelim test: 237496
Number of HSP's gapped (non-prelim): 27038
length of query: 2130
length of database: 575,637,011
effective HSP length: 112
effective length of query: 2018
effective length of database: 390,021,203
effective search space: 787062787654
effective search space used: 787062787654
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 80 (36.3 bits)

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