BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000624-TA|BGIBMGA000624-PA|IPR001452|Src homology-3, IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2, IPR003961|Fibronectin, type III, IPR003962|Fibronectin, type III subdomain, IPR007110|Immunoglobulin-like, IPR013098|Immunoglobulin I-set, IPR008957|Fibronectin, type III-like fold (2130 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|... 3397 0.0 UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes a... 1868 0.0 UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - ... 1773 0.0 UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora... 830 0.0 UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gamb... 793 0.0 UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isof... 388 e-106 UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Conn... 344 2e-92 UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin ... 318 8e-85 UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin -... 315 1e-83 UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin ... 312 9e-83 UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein;... 311 1e-82 UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Hom... 299 7e-79 UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whol... 287 3e-75 UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - ... 270 2e-70 UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whol... 268 1e-69 UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus... 266 3e-69 UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; ... 266 5e-69 UniRef50_UPI0000E460FC Cluster: PREDICTED: similar to Bent, part... 256 6e-66 UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole... 254 1e-65 UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep... 245 9e-63 UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whol... 244 2e-62 UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa... 235 1e-59 UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole... 231 2e-58 UniRef50_Q14324 Cluster: Myosin-binding protein C, fast-type; n=... 231 2e-58 UniRef50_UPI00015A6D36 Cluster: UPI00015A6D36 related cluster; n... 228 1e-57 UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome sh... 227 2e-57 UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella ve... 224 2e-56 UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whol... 222 7e-56 UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB... 219 9e-55 UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n... 215 1e-53 UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP000... 214 3e-53 UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Re... 213 4e-53 UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin ... 212 8e-53 UniRef50_UPI0000F1EF40 Cluster: PREDICTED: similar to novel immu... 198 2e-48 UniRef50_Q7YRF6 Cluster: Cardiac titin; n=4; Eutheria|Rep: Cardi... 193 4e-47 UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG3351... 193 4e-47 UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome sh... 192 7e-47 UniRef50_Q1JPV5 Cluster: Zgc:136545; n=3; Danio rerio|Rep: Zgc:1... 192 9e-47 UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin -... 192 1e-46 UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin ... 190 5e-46 UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein;... 186 4e-45 UniRef50_Q8N9C0 Cluster: Immunoglobulin superfamily member 22; n... 186 6e-45 UniRef50_UPI0000F33BB2 Cluster: Connectin; n=1; Bos taurus|Rep: ... 185 1e-44 UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscuri... 184 3e-44 UniRef50_A5PF15 Cluster: Novel protein similar to human obscurin... 182 7e-44 UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome sh... 182 1e-43 UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole... 180 4e-43 UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA... 178 1e-42 UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA... 176 6e-42 UniRef50_UPI0000ECA094 Cluster: eEF1A2 binding protein; n=3; Gal... 174 2e-41 UniRef50_Q8T104 Cluster: Projectin-like protein; n=1; Bombyx mor... 174 2e-41 UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB... 173 3e-41 UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel immu... 172 8e-41 UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA... 172 8e-41 UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=... 172 1e-40 UniRef50_Q7ZWM9 Cluster: LOC398550 protein; n=2; Xenopus|Rep: LO... 170 3e-40 UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - ... 170 3e-40 UniRef50_UPI00015A4170 Cluster: eEF1A2 binding protein; n=1; Dan... 170 4e-40 UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel he... 169 1e-39 UniRef50_Q4SK55 Cluster: Chromosome 2 SCAF14570, whole genome sh... 169 1e-39 UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG3... 168 2e-39 UniRef50_Q4RE91 Cluster: Chromosome undetermined SCAF15134, whol... 167 3e-39 UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-P... 164 3e-38 UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein;... 162 8e-38 UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome s... 162 8e-38 UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB... 162 1e-37 UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and ... 159 6e-37 UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35... 159 1e-36 UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP000... 158 1e-36 UniRef50_Q86VF2 Cluster: EEF1A2 binding protein; n=9; Euteleosto... 157 2e-36 UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gamb... 157 3e-36 UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella ve... 155 1e-35 UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|... 153 4e-35 UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome s... 152 1e-34 UniRef50_Q676A1 Cluster: Cardiac myosin-binding protein C; n=1; ... 151 2e-34 UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus C... 150 4e-34 UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: H... 150 4e-34 UniRef50_Q4SM88 Cluster: Chromosome 3 SCAF14553, whole genome sh... 149 6e-34 UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n... 148 1e-33 UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella ve... 148 1e-33 UniRef50_UPI00005A1317 Cluster: PREDICTED: similar to eEF1A2 bin... 146 4e-33 UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopall... 146 4e-33 UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: C... 145 1e-32 UniRef50_P54296 Cluster: Myomesin-2; n=33; Euteleostomi|Rep: Myo... 144 3e-32 UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopteryg... 142 9e-32 UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin... 142 1e-31 UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella ve... 141 2e-31 UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome s... 140 4e-31 UniRef50_UPI0000F2E010 Cluster: PREDICTED: similar to chondroiti... 139 7e-31 UniRef50_P52179 Cluster: Myomesin-1; n=19; Euteleostomi|Rep: Myo... 139 7e-31 UniRef50_Q14896 Cluster: Myosin-binding protein C, cardiac-type;... 139 9e-31 UniRef50_UPI000065FB77 Cluster: Myomesin-1 (190 kDa titin-associ... 138 1e-30 UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscl... 138 2e-30 UniRef50_Q4RH24 Cluster: Chromosome 18 SCAF15072, whole genome s... 136 5e-30 UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscl... 136 5e-30 UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella ve... 136 8e-30 UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome ... 135 1e-29 UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscl... 135 1e-29 UniRef50_UPI0000F201CC Cluster: PREDICTED: similar to Myomesin 2... 135 1e-29 UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndr... 135 1e-29 UniRef50_A7DN46 Cluster: Fibronectin, type III domain protein pr... 134 3e-29 UniRef50_Q4STB1 Cluster: Chromosome 11 SCAF14249, whole genome s... 134 3e-29 UniRef50_UPI0000660A1C Cluster: Homolog of Gallus gallus "Myosin... 132 8e-29 UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-li... 130 4e-28 UniRef50_UPI0000E8095E Cluster: PREDICTED: similar to novel immu... 129 7e-28 UniRef50_UPI0000ECB822 Cluster: Obscurin-like protein 1 precurso... 128 2e-27 UniRef50_Q4RH47 Cluster: Chromosome undetermined SCAF15069, whol... 128 2e-27 UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladi... 127 3e-27 UniRef50_UPI000065E224 Cluster: eEF1A2 binding protein; n=2; Tak... 127 4e-27 UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar... 127 4e-27 UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep: P... 127 4e-27 UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion mole... 126 9e-27 UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella ve... 126 9e-27 UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleosto... 126 9e-27 UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p... 125 1e-26 UniRef50_UPI000066030F Cluster: Myomesin-2 (M-protein) (165 kDa ... 124 3e-26 UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome sh... 123 5e-26 UniRef50_UPI0000F1EA79 Cluster: PREDICTED: hypothetical protein;... 123 6e-26 UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin -... 122 1e-25 UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|... 122 1e-25 UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n... 121 3e-25 UniRef50_Q17AE8 Cluster: Titin; n=3; Culicidae|Rep: Titin - Aede... 120 3e-25 UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 pr... 120 4e-25 UniRef50_A0RX14 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-24 UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome sh... 118 2e-24 UniRef50_Q53EP0 Cluster: Fibronectin type III domain-containing ... 117 3e-24 UniRef50_A7RGL5 Cluster: Predicted protein; n=1; Nematostella ve... 117 4e-24 UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella ve... 116 5e-24 UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep... 115 1e-23 UniRef50_Q9Y2H6 Cluster: Fibronectin type-III domain-containing ... 115 1e-23 UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemi... 115 2e-23 UniRef50_UPI0000E46511 Cluster: PREDICTED: similar to Fibronecti... 114 2e-23 UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precur... 114 2e-23 UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein;... 113 4e-23 UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, memb... 113 4e-23 UniRef50_P98160 Cluster: Basement membrane-specific heparan sulf... 113 5e-23 UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein;... 113 7e-23 UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein;... 112 9e-23 UniRef50_UPI0000D5788D Cluster: PREDICTED: similar to CG31738-PB... 112 9e-23 UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd prot... 112 1e-22 UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger ... 112 1e-22 UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep: Conn... 112 1e-22 UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|R... 112 1e-22 UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone speci... 111 2e-22 UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA,... 111 2e-22 UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphat... 111 3e-22 UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n... 110 4e-22 UniRef50_Q172S1 Cluster: Stretchin-mlck; n=1; Aedes aegypti|Rep:... 110 4e-22 UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin... 110 5e-22 UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella ve... 110 5e-22 UniRef50_Q62234 Cluster: Myomesin-1; n=32; cellular organisms|Re... 109 6e-22 UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gal... 109 8e-22 UniRef50_Q4STB0 Cluster: Chromosome 11 SCAF14249, whole genome s... 109 8e-22 UniRef50_A6H8Q3 Cluster: Zgc:165344 protein; n=9; Clupeocephala|... 108 1e-21 UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA... 107 3e-21 UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphat... 107 3e-21 UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleosto... 107 3e-21 UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|... 107 4e-21 UniRef50_Q4RFP3 Cluster: Chromosome 16 SCAF15113, whole genome s... 106 6e-21 UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Eut... 106 6e-21 UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|... 106 8e-21 UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=2... 105 1e-20 UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2... 105 2e-20 UniRef50_UPI0000DB7210 Cluster: PREDICTED: similar to Stretchin-... 104 2e-20 UniRef50_Q4S0Y7 Cluster: Chromosome 5 SCAF14773, whole genome sh... 104 3e-20 UniRef50_A6NI63 Cluster: Uncharacterized protein MYOM3; n=42; Te... 104 3e-20 UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundab... 103 4e-20 UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC... 103 4e-20 UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;... 103 5e-20 UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA ... 103 5e-20 UniRef50_Q15772 Cluster: Striated muscle preferentially expresse... 103 5e-20 UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|... 103 5e-20 UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout... 103 7e-20 UniRef50_Q4SK53 Cluster: Chromosome 2 SCAF14570, whole genome sh... 103 7e-20 UniRef50_A7RZM7 Cluster: Predicted protein; n=1; Nematostella ve... 103 7e-20 UniRef50_Q4S5Q4 Cluster: Chromosome 9 SCAF14729, whole genome sh... 102 1e-19 UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell ad... 101 2e-19 UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome s... 101 2e-19 UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome s... 101 3e-19 UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA... 100 4e-19 UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-... 100 5e-19 UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG3... 100 5e-19 UniRef50_Q696W0 Cluster: Striated muscle preferentially expresse... 100 5e-19 UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor t... 99 7e-19 UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 -... 100 9e-19 UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleosto... 100 9e-19 UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor ... 99 1e-18 UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precur... 99 1e-18 UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan su... 98 2e-18 UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 98 2e-18 UniRef50_A1L1W0 Cluster: Zgc:158442; n=3; Danio rerio|Rep: Zgc:1... 98 2e-18 UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanog... 98 2e-18 UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precurs... 98 3e-18 UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kD... 98 3e-18 UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote... 97 4e-18 UniRef50_Q177W1 Cluster: Factor for adipocyte differentiation; n... 97 4e-18 UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Eut... 97 4e-18 UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin p... 97 5e-18 UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; E... 97 5e-18 UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whol... 97 6e-18 UniRef50_Q1CVL1 Cluster: FG-GAP repeat/fibronectin type III doma... 97 6e-18 UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whol... 96 8e-18 UniRef50_Q9N3X8 Cluster: Protein sidekick homolog precursor; n=2... 96 8e-18 UniRef50_Q13203 Cluster: Myosin-binding protein H; n=35; Tetrapo... 96 8e-18 UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like p... 96 8e-18 UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Da... 96 1e-17 UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9... 96 1e-17 UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eum... 95 1e-17 UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB... 95 2e-17 UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttn... 95 2e-17 UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome s... 95 2e-17 UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio reri... 95 2e-17 UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygo... 95 2e-17 UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: ... 95 2e-17 UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 ... 95 2e-17 UniRef50_UPI000155E24A Cluster: PREDICTED: similar to myosin bin... 94 3e-17 UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin lig... 94 3e-17 UniRef50_A4AI84 Cluster: Serine protease, subtilase family prote... 94 3e-17 UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin... 94 4e-17 UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc... 94 4e-17 UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; E... 94 4e-17 UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precurs... 94 4e-17 UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome s... 93 6e-17 UniRef50_A7RYG4 Cluster: Predicted protein; n=1; Nematostella ve... 93 6e-17 UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM pro... 93 1e-16 UniRef50_UPI0000DA2C8C Cluster: PREDICTED: similar to myosin bin... 93 1e-16 UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whol... 92 1e-16 UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome sh... 92 1e-16 UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ ... 92 1e-16 UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle pro... 91 2e-16 UniRef50_UPI0000D9D1DB Cluster: PREDICTED: similar to obscurin, ... 91 2e-16 UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome sh... 91 3e-16 UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome s... 91 3e-16 UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precurs... 91 3e-16 UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella ve... 91 4e-16 UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled p... 90 5e-16 UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Ne... 90 5e-16 UniRef50_Q05D81 Cluster: MYLK protein; n=14; Eutheria|Rep: MYLK ... 90 5e-16 UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; C... 90 5e-16 UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whol... 90 7e-16 UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome sh... 90 7e-16 UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin... 89 9e-16 UniRef50_UPI00015A6655 Cluster: myomesin family, member 3; n=6; ... 89 9e-16 UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella ve... 89 9e-16 UniRef50_UPI0000F2C7E8 Cluster: PREDICTED: similar to myomesin 1... 89 1e-15 UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin ... 89 1e-15 UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic a... 89 1e-15 UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whol... 89 1e-15 UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin... 89 2e-15 UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebr... 88 2e-15 UniRef50_Q4RZE9 Cluster: Chromosome undetermined SCAF14935, whol... 88 2e-15 UniRef50_A7RGL3 Cluster: Predicted protein; n=1; Nematostella ve... 88 2e-15 UniRef50_A6NGQ3 Cluster: Uncharacterized protein OBSCN; n=2; Hom... 88 2e-15 UniRef50_O97394 Cluster: Protein sidekick precursor; n=9; Endopt... 88 2e-15 UniRef50_Q9VN14 Cluster: Contactin precursor; n=4; Endopterygota... 88 2e-15 UniRef50_UPI00015B62AB Cluster: PREDICTED: similar to CG18255-PA... 88 3e-15 UniRef50_UPI0000E4900E Cluster: PREDICTED: similar to transmembr... 88 3e-15 UniRef50_Q4S6A5 Cluster: Chromosome 9 SCAF14729, whole genome sh... 88 3e-15 UniRef50_Q8T102 Cluster: Titin-like protein; n=3; Bombyx mori|Re... 88 3e-15 UniRef50_O00533 Cluster: Neural cell adhesion molecule L1-like p... 87 4e-15 UniRef50_UPI0000F20573 Cluster: PREDICTED: similar to hCG1644439... 87 5e-15 UniRef50_UPI0000D8D180 Cluster: UPI0000D8D180 related cluster; n... 87 5e-15 UniRef50_UPI00015B6345 Cluster: PREDICTED: similar to CG33141-PB... 87 7e-15 UniRef50_UPI00015B5487 Cluster: PREDICTED: similar to leucine-ri... 87 7e-15 UniRef50_Q4T8B2 Cluster: Chromosome undetermined SCAF7849, whole... 87 7e-15 UniRef50_Q4RYE5 Cluster: Chromosome 2 SCAF14976, whole genome sh... 87 7e-15 UniRef50_Q17BD3 Cluster: Roundabout 1; n=3; Culicidae|Rep: Round... 87 7e-15 UniRef50_O18465 Cluster: Tractin; n=7; Coelomata|Rep: Tractin - ... 87 7e-15 UniRef50_A1XCJ3 Cluster: RoboA; n=1; Schmidtea mediterranea|Rep:... 87 7e-15 UniRef50_Q92626 Cluster: Peroxidasin homolog; n=49; Eumetazoa|Re... 87 7e-15 UniRef50_Q174G3 Cluster: Roundabout; n=5; Aedes aegypti|Rep: Rou... 86 9e-15 UniRef50_A7SSL0 Cluster: Predicted protein; n=1; Nematostella ve... 86 9e-15 UniRef50_UPI0000DB7559 Cluster: PREDICTED: similar to sticks and... 86 1e-14 UniRef50_UPI000065E234 Cluster: Homolog of Homo sapiens "OTTHUMP... 86 1e-14 UniRef50_Q7ZY97 Cluster: Tn3 protein; n=2; Xenopus|Rep: Tn3 prot... 86 1e-14 UniRef50_P32004 Cluster: Neural cell adhesion molecule L1 precur... 86 1e-14 UniRef50_UPI0000DB7FD0 Cluster: PREDICTED: similar to roundabout... 85 2e-14 UniRef50_Q3MHW8 Cluster: PALLD protein; n=7; Euteleostomi|Rep: P... 85 2e-14 UniRef50_UPI0000E4A418 Cluster: PREDICTED: similar to axonin-1; ... 85 2e-14 UniRef50_UPI0000DB6D94 Cluster: PREDICTED: similar to CG33274-PA... 85 2e-14 UniRef50_UPI0000D55947 Cluster: PREDICTED: similar to CG33141-PA... 85 2e-14 UniRef50_UPI0000F2BDAE Cluster: PREDICTED: similar to hCG1996527... 85 3e-14 UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 85 3e-14 UniRef50_UPI0000DB6DF8 Cluster: PREDICTED: similar to leucine-ri... 85 3e-14 UniRef50_UPI0000D5796D Cluster: PREDICTED: similar to CG31190-PA... 85 3e-14 UniRef50_UPI0000D56E5C Cluster: PREDICTED: similar to CG5423-PA;... 85 3e-14 UniRef50_Q8IVU1 Cluster: Putative neuronal cell adhesion molecul... 85 3e-14 UniRef50_UPI0000E46E64 Cluster: PREDICTED: similar to SAPS287; n... 84 4e-14 UniRef50_Q9Y2A5 Cluster: Serine/threonine-protein kinase Duet; n... 84 4e-14 UniRef50_UPI000155CDCD Cluster: PREDICTED: similar to adlican; n... 84 5e-14 UniRef50_UPI0000DB6E73 Cluster: PREDICTED: similar to CG31190-PB... 84 5e-14 UniRef50_Q17BD5 Cluster: Roundabout; n=1; Aedes aegypti|Rep: Rou... 84 5e-14 UniRef50_A7DN09 Cluster: Fibronectin, type III domain protein pr... 84 5e-14 UniRef50_UPI0000EB3119 Cluster: UPI0000EB3119 related cluster; n... 83 6e-14 UniRef50_UPI0000F20186 Cluster: PREDICTED: similar to cell adhes... 83 8e-14 UniRef50_Q7KSE9 Cluster: CG31190-PB, isoform B; n=4; Diptera|Rep... 83 8e-14 UniRef50_Q17AE6 Cluster: Kinesin motor protein, putative; n=2; C... 83 8e-14 UniRef50_UPI00006607E8 Cluster: Homolog of Homo sapiens "OTTHUMP... 83 1e-13 UniRef50_Q7PRK4 Cluster: ENSANGP00000000600; n=1; Anopheles gamb... 83 1e-13 UniRef50_Q1JUB3 Cluster: L1-like cell adhesion molecule; n=1; Du... 83 1e-13 UniRef50_A7T084 Cluster: Predicted protein; n=1; Nematostella ve... 83 1e-13 UniRef50_Q8N237 Cluster: CDNA FLJ34965 fis, clone NTONG2004308; ... 83 1e-13 UniRef50_Q4SR23 Cluster: Chromosome 11 SCAF14528, whole genome s... 82 1e-13 UniRef50_Q4S556 Cluster: Chromosome 6 SCAF14737, whole genome sh... 82 1e-13 UniRef50_Q4RKT9 Cluster: Chromosome 1 SCAF15025, whole genome sh... 82 1e-13 UniRef50_Q9VJJ9 Cluster: CG31738-PB, isoform B; n=3; Drosophila ... 82 1e-13 UniRef50_UPI00005A24A2 Cluster: PREDICTED: similar to Glyceralde... 82 2e-13 UniRef50_UPI0000ECA411 Cluster: UPI0000ECA411 related cluster; n... 82 2e-13 UniRef50_A7S5L2 Cluster: Predicted protein; n=1; Nematostella ve... 82 2e-13 UniRef50_Q12860 Cluster: Contactin-1 precursor; n=31; Euteleosto... 82 2e-13 UniRef50_UPI0000F1E7B2 Cluster: PREDICTED: hypothetical protein;... 81 2e-13 UniRef50_Q4SPP8 Cluster: Chromosome 16 SCAF14537, whole genome s... 81 2e-13 UniRef50_Q2VWP7 Cluster: Protogenin homolog; n=32; Euteleostomi|... 81 2e-13 UniRef50_Q02246 Cluster: Contactin-2 precursor; n=38; Euteleosto... 81 2e-13 UniRef50_UPI00006A0C09 Cluster: obscurin, cytoskeletal calmoduli... 81 3e-13 UniRef50_UPI00006A0696 Cluster: DDM36; n=4; Tetrapoda|Rep: DDM36... 81 3e-13 UniRef50_Q9W4Y3 Cluster: CG33950-PF, isoform F; n=13; Coelomata|... 81 3e-13 UniRef50_A7SVH5 Cluster: Predicted protein; n=1; Nematostella ve... 81 3e-13 UniRef50_UPI00015B41E3 Cluster: PREDICTED: similar to fasciclin ... 81 4e-13 UniRef50_UPI0000E48846 Cluster: PREDICTED: similar to CG1915-PC;... 81 4e-13 UniRef50_UPI00006A08CF Cluster: myomesin family, member 3; n=1; ... 81 4e-13 UniRef50_Q8MQ86 Cluster: Putative uncharacterized protein F02G3.... 81 4e-13 UniRef50_UPI0000DB72ED Cluster: PREDICTED: similar to CG33950-PD... 80 6e-13 UniRef50_Q695L3 Cluster: Obscurin-MLCK; n=5; Clupeocephala|Rep: ... 80 6e-13 UniRef50_Q4SF99 Cluster: Chromosome undetermined SCAF14606, whol... 80 6e-13 UniRef50_Q4RHM3 Cluster: Chromosome 19 SCAF15045, whole genome s... 80 6e-13 UniRef50_A0S6W8 Cluster: Hemicentin-like protein 2; n=2; Spodopt... 80 6e-13 UniRef50_Q4SHH6 Cluster: Chromosome 5 SCAF14581, whole genome sh... 80 8e-13 UniRef50_Q4RHM4 Cluster: Chromosome 19 SCAF15045, whole genome s... 80 8e-13 UniRef50_Q6UXM1 Cluster: Leucine-rich repeats and immunoglobulin... 80 8e-13 UniRef50_Q96JA1 Cluster: Leucine-rich repeats and immunoglobulin... 80 8e-13 UniRef50_Q4RE93 Cluster: Chromosome undetermined SCAF15134, whol... 79 1e-12 UniRef50_A7RQE6 Cluster: Predicted protein; n=3; Nematostella ve... 79 1e-12 UniRef50_A1Z920 Cluster: CG8581-PA, isoform A; n=8; Diptera|Rep:... 79 1e-12 UniRef50_UPI0000E4617C Cluster: PREDICTED: similar to novel immu... 79 1e-12 UniRef50_Q1ENI8 Cluster: Peroxidasin (Drosophila peroxidase) hom... 79 1e-12 UniRef50_Q7PQF4 Cluster: ENSANGP00000011303; n=1; Anopheles gamb... 79 2e-12 UniRef50_A7SQD9 Cluster: Predicted protein; n=2; Nematostella ve... 79 2e-12 UniRef50_A7DN16 Cluster: Fibronectin, type III domain protein; n... 79 2e-12 UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 79 2e-12 UniRef50_Q8UVD6 Cluster: Brother of CDO; n=2; Danio rerio|Rep: B... 78 2e-12 UniRef50_Q4RVZ3 Cluster: Chromosome 9 SCAF14991, whole genome sh... 78 2e-12 UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ... 78 3e-12 UniRef50_Q5W433 Cluster: Sialic-acid binding protein-4 precursor... 78 3e-12 UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 77 4e-12 UniRef50_Q17AC3 Cluster: Leucine-rich transmembrane protein; n=2... 77 4e-12 UniRef50_UPI0001556498 Cluster: PREDICTED: similar to obscurin, ... 77 5e-12 UniRef50_UPI0000519A30 Cluster: PREDICTED: similar to Peroxidasi... 77 5e-12 UniRef50_Q4STY2 Cluster: Chromosome 10 SCAF14066, whole genome s... 77 5e-12 UniRef50_UPI0000EBE875 Cluster: PREDICTED: similar to Gene model... 77 7e-12 UniRef50_UPI000069F41E Cluster: Myosin light chain kinase, smoot... 77 7e-12 UniRef50_Q7Z553 Cluster: MAM domain-containing glycosylphosphati... 77 7e-12 UniRef50_UPI0000DB6DA9 Cluster: PREDICTED: similar to CG32387-PB... 76 9e-12 UniRef50_UPI0000D57760 Cluster: PREDICTED: similar to leucine-ri... 76 9e-12 UniRef50_Q4RRD1 Cluster: Chromosome 16 SCAF15002, whole genome s... 76 9e-12 UniRef50_Q6DFV6 Cluster: Gene model 784,; n=13; Murinae|Rep: Gen... 76 9e-12 UniRef50_Q4SIF9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 76 1e-11 UniRef50_Q4RKK6 Cluster: Chromosome 5 SCAF15028, whole genome sh... 76 1e-11 UniRef50_Q5W9G3 Cluster: LAR splice variant 1; n=24; Eutheria|Re... 76 1e-11 UniRef50_Q8TDY8 Cluster: Neighbor of punc e11 precursor; n=23; T... 76 1e-11 UniRef50_Q4KMG0 Cluster: Cell adhesion molecule-related/down-reg... 76 1e-11 UniRef50_UPI00015A663C Cluster: myomesin family, member 3; n=4; ... 75 2e-11 UniRef50_UPI00006A231D Cluster: Brother of CDO precursor (Protei... 75 2e-11 UniRef50_Q4T1T8 Cluster: Chromosome 2 SCAF10486, whole genome sh... 75 2e-11 UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece... 75 2e-11 UniRef50_Q17G58 Cluster: Lachesin; n=3; Culicidae|Rep: Lachesin ... 75 2e-11 UniRef50_A7SVH4 Cluster: Predicted protein; n=2; Nematostella ve... 75 2e-11 UniRef50_UPI0000F33D9D Cluster: Perlecan; n=1; Bos taurus|Rep: P... 75 3e-11 UniRef50_O44329 Cluster: Receptor tyrosine phosphatase; n=1; Hir... 75 3e-11 UniRef50_UPI0000D55E60 Cluster: PREDICTED: similar to CG32796-PB... 74 4e-11 UniRef50_UPI00015A4156 Cluster: Neogenin precursor.; n=1; Danio ... 74 4e-11 UniRef50_UPI000069DD8B Cluster: Leucine-rich repeats and immunog... 74 4e-11 UniRef50_Q308M3 Cluster: Protein tyrosine phosphatase receptor t... 74 4e-11 UniRef50_Q18066 Cluster: Disorganized muscle protein 1; n=4; Chr... 74 4e-11 UniRef50_P05548 Cluster: CAVP-target protein; n=1; Branchiostoma... 74 4e-11 UniRef50_Q71B05 Cluster: Roundabout-like protein 4; n=5; Danio r... 74 5e-11 UniRef50_Q4RY92 Cluster: Chromosome 3 SCAF14978, whole genome sh... 74 5e-11 UniRef50_A7RT95 Cluster: Predicted protein; n=1; Nematostella ve... 74 5e-11 UniRef50_A7RK32 Cluster: Predicted protein; n=2; Nematostella ve... 74 5e-11 UniRef50_O94898 Cluster: Leucine-rich repeats and immunoglobulin... 74 5e-11 UniRef50_Q4S969 Cluster: Chromosome 3 SCAF14700, whole genome sh... 73 7e-11 UniRef50_Q4RRS5 Cluster: Chromosome 16 SCAF15002, whole genome s... 73 7e-11 UniRef50_A7MB72 Cluster: MGC166429 protein; n=4; Tetrapoda|Rep: ... 73 7e-11 UniRef50_UPI0000DB6DA8 Cluster: PREDICTED: similar to CG32387-PB... 73 9e-11 UniRef50_UPI0000D9D2C3 Cluster: PREDICTED: similar to peroxidasi... 73 9e-11 UniRef50_Q58EP4 Cluster: LOC572412 protein; n=2; Danio rerio|Rep... 73 9e-11 UniRef50_Q4RVM1 Cluster: Chromosome 9 SCAF14991, whole genome sh... 73 9e-11 UniRef50_A4X2B3 Cluster: Fibronectin, type III domain protein; n... 73 9e-11 UniRef50_A0JUG0 Cluster: Fibronectin, type III domain protein pr... 73 9e-11 UniRef50_Q9BWV1 Cluster: Brother of CDO precursor; n=27; Euteleo... 73 9e-11 UniRef50_UPI0000F20574 Cluster: PREDICTED: similar to glomerular... 73 1e-10 UniRef50_UPI0000ECD748 Cluster: UPI0000ECD748 related cluster; n... 73 1e-10 UniRef50_Q4SPP9 Cluster: Chromosome 16 SCAF14537, whole genome s... 73 1e-10 UniRef50_Q4RVM0 Cluster: Chromosome 9 SCAF14991, whole genome sh... 73 1e-10 UniRef50_Q2EGT7 Cluster: Limbic system-associated membrane prote... 73 1e-10 UniRef50_P22648 Cluster: Fasciclin-2 precursor; n=1; Schistocerc... 73 1e-10 UniRef50_Q7SY58 Cluster: Muscle, skeletal, receptor tyrosine kin... 72 2e-10 UniRef50_Q592R0 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-10 UniRef50_Q0E9F2 Cluster: CG33141-PB, isoform B; n=9; Diptera|Rep... 72 2e-10 UniRef50_Q13449 Cluster: Limbic system-associated membrane prote... 72 2e-10 UniRef50_UPI0000D560FB Cluster: PREDICTED: similar to CG1084-PA;... 72 2e-10 UniRef50_Q9VCT4 Cluster: CG6669-PA; n=8; Diptera|Rep: CG6669-PA ... 72 2e-10 UniRef50_Q7PRJ5 Cluster: ENSANGP00000024207; n=3; Endopterygota|... 72 2e-10 UniRef50_A7RTW2 Cluster: Predicted protein; n=1; Nematostella ve... 72 2e-10 UniRef50_A7RGL6 Cluster: Predicted protein; n=1; Nematostella ve... 72 2e-10 UniRef50_Q26475 Cluster: REGA-1 protein precursor; n=1; Schistoc... 71 3e-10 UniRef50_O97137 Cluster: Fasciclin II transmembrane isoform; n=3... 71 3e-10 UniRef50_A7SS32 Cluster: Predicted protein; n=6; Nematostella ve... 71 3e-10 UniRef50_Q18245 Cluster: Ig-like and fibronectin type-III domain... 71 3e-10 UniRef50_Q7TPW1 Cluster: Nexilin; n=12; Euteleostomi|Rep: Nexili... 71 3e-10 UniRef50_P34082 Cluster: Fasciclin-2 precursor; n=7; Diptera|Rep... 71 3e-10 UniRef50_UPI0000E4754C Cluster: PREDICTED: similar to DDM36; n=1... 71 4e-10 UniRef50_Q0ZGT2 Cluster: Nexilin; n=25; Euteleostomi|Rep: Nexili... 71 4e-10 UniRef50_UPI00015B5ECA Cluster: PREDICTED: similar to rCG56583; ... 71 5e-10 UniRef50_UPI0000EB292A Cluster: Leucine-rich repeats and immunog... 71 5e-10 UniRef50_O18466 Cluster: LeechCAM; n=1; Hirudo medicinalis|Rep: ... 71 5e-10 UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 71 5e-10 UniRef50_UPI00004D1686 Cluster: Neogenin precursor.; n=1; Xenopu... 70 6e-10 UniRef50_Q4RQR3 Cluster: Chromosome 2 SCAF15004, whole genome sh... 70 6e-10 UniRef50_Q16UD9 Cluster: Sidestep protein; n=1; Aedes aegypti|Re... 70 6e-10 UniRef50_A7T5G7 Cluster: Predicted protein; n=1; Nematostella ve... 70 6e-10 UniRef50_A2A344 Cluster: ADAMTS-like 1; n=29; Euteleostomi|Rep: ... 70 6e-10 UniRef50_Q03696 Cluster: Neuronal-glial cell adhesion molecule p... 70 6e-10 UniRef50_UPI0000F1E5DD Cluster: PREDICTED: hypothetical protein;... 70 8e-10 UniRef50_UPI0000F1DA2E Cluster: PREDICTED: hypothetical protein;... 70 8e-10 UniRef50_Q7QJK6 Cluster: ENSANGP00000010870; n=1; Anopheles gamb... 70 8e-10 UniRef50_Q7QCP2 Cluster: ENSANGP00000010242; n=1; Anopheles gamb... 70 8e-10 UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 70 8e-10 UniRef50_UPI0000DB6DA7 Cluster: PREDICTED: similar to Protein ty... 69 1e-09 UniRef50_UPI000065EECD Cluster: Homolog of Brachydanio rerio "Ob... 69 1e-09 UniRef50_UPI0000E80F57 Cluster: PREDICTED: hypothetical protein;... 69 1e-09 UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 69 1e-09 UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 69 1e-09 UniRef50_UPI0000F1DED3 Cluster: PREDICTED: similar to sialic-aci... 69 1e-09 UniRef50_UPI0000D9DD6E Cluster: PREDICTED: similar to hemicentin... 69 1e-09 UniRef50_A2BEV6 Cluster: Novel protein; n=8; Danio rerio|Rep: No... 69 1e-09 UniRef50_UPI00015B5C2D Cluster: PREDICTED: similar to lachesin; ... 69 2e-09 UniRef50_UPI0000E49A7A Cluster: PREDICTED: hypothetical protein,... 69 2e-09 UniRef50_A7RYG0 Cluster: Predicted protein; n=1; Nematostella ve... 69 2e-09 UniRef50_P15364 Cluster: Protein amalgam precursor; n=6; melanog... 69 2e-09 UniRef50_UPI0000E4747A Cluster: PREDICTED: similar to neuroglian... 68 2e-09 UniRef50_Q4RU88 Cluster: Chromosome 1 SCAF14995, whole genome sh... 68 2e-09 UniRef50_Q9V787 Cluster: Hibris; n=4; Sophophora|Rep: Hibris - D... 68 3e-09 UniRef50_Q5WRR1 Cluster: Wrapper/rega-1/klingon homolog protein ... 68 3e-09 UniRef50_UPI00006A0174 Cluster: Roundabout homolog 4 precursor (... 67 4e-09 UniRef50_Q4ACB4 Cluster: Mahya; n=3; Endopterygota|Rep: Mahya - ... 67 4e-09 UniRef50_UPI00015B48D7 Cluster: PREDICTED: similar to lachesin; ... 66 8e-09 UniRef50_UPI0000DBF155 Cluster: UPI0000DBF155 related cluster; n... 66 8e-09 UniRef50_Q9VMN6 Cluster: CG31646-PA; n=9; Endopterygota|Rep: CG3... 66 8e-09 UniRef50_Q3SA91 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-09 UniRef50_Q97Z97 Cluster: Kelch domain-containing protein SSO1033... 66 8e-09 UniRef50_UPI00015B50B3 Cluster: PREDICTED: similar to cell adhes... 66 1e-08 UniRef50_UPI0000546958 Cluster: PREDICTED: hypothetical protein;... 66 1e-08 UniRef50_UPI0000D8BAD9 Cluster: UPI0000D8BAD9 related cluster; n... 66 1e-08 UniRef50_Q4RFN0 Cluster: Chromosome 16 SCAF15113, whole genome s... 66 1e-08 UniRef50_Q9BN17 Cluster: Echinoid; n=10; Diptera|Rep: Echinoid -... 66 1e-08 UniRef50_A7TCD9 Cluster: Predicted protein; n=1; Nematostella ve... 66 1e-08 UniRef50_UPI0000F21178 Cluster: PREDICTED: hypothetical protein;... 66 1e-08 UniRef50_Q4TAJ7 Cluster: Chromosome undetermined SCAF7304, whole... 66 1e-08 UniRef50_UPI0000F1D4AE Cluster: PREDICTED: similar to sidekick 1... 65 2e-08 UniRef50_UPI00005A3E04 Cluster: PREDICTED: similar to protein ty... 65 2e-08 UniRef50_UPI000069F509 Cluster: Uncharacterized protein C9orf94 ... 65 2e-08 UniRef50_UPI000069DA70 Cluster: Protein tyrosine phosphatase RQ;... 65 2e-08 UniRef50_Q4SYB6 Cluster: Chromosome 11 SCAF12108, whole genome s... 65 2e-08 UniRef50_Q4RKU0 Cluster: Chromosome 1 SCAF15025, whole genome sh... 65 2e-08 UniRef50_Q59E14 Cluster: CG33543-PC; n=3; Sophophora|Rep: CG3354... 65 2e-08 UniRef50_UPI0000F20868 Cluster: PREDICTED: similar to sialic-aci... 65 2e-08 UniRef50_UPI0000D55B25 Cluster: PREDICTED: similar to CG6669-PA;... 65 2e-08 UniRef50_UPI0000ECA5E8 Cluster: Transmembrane and immunoglobulin... 65 2e-08 UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R... 65 2e-08 UniRef50_A7SM31 Cluster: Predicted protein; n=1; Nematostella ve... 65 2e-08 UniRef50_O75445 Cluster: Usherin precursor; n=34; Eukaryota|Rep:... 65 2e-08 UniRef50_UPI0000E25314 Cluster: PREDICTED: similar to fast MyBP-... 64 3e-08 UniRef50_Q4STG8 Cluster: Chromosome undetermined SCAF14228, whol... 64 3e-08 UniRef50_Q7QEI6 Cluster: ENSANGP00000020451; n=1; Anopheles gamb... 64 3e-08 UniRef50_Q22040 Cluster: Putative uncharacterized protein SSSD1.... 64 3e-08 UniRef50_UPI0000EBE6C5 Cluster: PREDICTED: hypothetical protein;... 64 4e-08 UniRef50_UPI0000E48EAE Cluster: PREDICTED: similar to neuronal m... 64 4e-08 UniRef50_Q4TAD3 Cluster: Chromosome undetermined SCAF7373, whole... 64 4e-08 UniRef50_Q2WF53 Cluster: Neurotrimin; n=9; Clupeocephala|Rep: Ne... 64 4e-08 UniRef50_Q9UPX0 Cluster: Protein turtle homolog B precursor; n=2... 64 4e-08 UniRef50_Q7Z3B1 Cluster: Neuronal growth regulator 1 precursor; ... 64 4e-08 UniRef50_UPI00015B5C00 Cluster: PREDICTED: similar to VEGFR-A sp... 64 5e-08 UniRef50_Q9P2J2 Cluster: Protein turtle homolog A precursor; n=2... 64 5e-08 UniRef50_UPI0000E4A429 Cluster: PREDICTED: similar to guanine de... 63 7e-08 UniRef50_UPI000065EA6D Cluster: Homolog of Brachydanio rerio "Ro... 63 7e-08 UniRef50_Q4SUX1 Cluster: Chromosome undetermined SCAF13836, whol... 63 7e-08 UniRef50_Q4SI43 Cluster: Chromosome 5 SCAF14581, whole genome sh... 63 7e-08 UniRef50_A4JYK0 Cluster: Si:dkey-24p1.1; n=3; Danio rerio|Rep: S... 63 7e-08 UniRef50_Q09165 Cluster: Mesocentin precursor; n=5; Bilateria|Re... 63 7e-08 UniRef50_UPI0000E470DC Cluster: PREDICTED: hypothetical protein,... 63 9e-08 UniRef50_Q4SL83 Cluster: Chromosome 7 SCAF14557, whole genome sh... 63 9e-08 UniRef50_A7SQE0 Cluster: Predicted protein; n=1; Nematostella ve... 63 9e-08 UniRef50_UPI00005889C1 Cluster: PREDICTED: similar to neural adh... 62 1e-07 UniRef50_UPI00004D96E1 Cluster: adlican; n=1; Xenopus tropicalis... 62 1e-07 UniRef50_Q9TWA6 Cluster: APCAM=CELL adhesion molecule from CDNA ... 62 1e-07 UniRef50_Q8WR45 Cluster: Immunoglobulin domain-containing protei... 62 1e-07 UniRef50_Q059D2 Cluster: IP03328p; n=3; Endopterygota|Rep: IP033... 62 1e-07 UniRef50_A7T347 Cluster: Predicted protein; n=7; Nematostella ve... 62 1e-07 UniRef50_Q21043 Cluster: Putative uncharacterized protein pxn-2;... 62 2e-07 >UniRef50_Q8T101 Cluster: Titin-like protein; n=4; Endopterygota|Rep: Titin-like protein - Bombyx mori (Silk moth) Length = 3354 Score = 3397 bits (8431), Expect = 0.0 Identities = 1634/1731 (94%), Positives = 1637/1731 (94%), Gaps = 28/1731 (1%) Query: 413 TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ 472 TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ Sbjct: 1639 TPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQ 1698 Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ Sbjct: 1699 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 1758 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA Sbjct: 1759 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 1818 Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652 SSTTELIVEAPLSDHGSEMTV ADILEGIPPTFSKKPKAQYVDEGSDIL Sbjct: 1819 SSTTELIVEAPLSDHGSEMTVLSRKSLSRESSLADILEGIPPTFSKKPKAQYVDEGSDIL 1878 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA Sbjct: 1879 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 1938 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN Sbjct: 1939 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 1998 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP Sbjct: 1999 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 2058 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 PLFINRFQEITVKEKGTIKLVARVT NPVPSITWYRNNEIISPSETITQNFDGENIELVI Sbjct: 2059 PLFINRFQEITVKEKGTIKLVARVTGNPVPSITWYRNNEIISPSETITQNFDGENIELVI 2118 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT Sbjct: 2119 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 2178 Query: 953 SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012 SHTVSTKWYHNKKEISGMDHREIIQEGR DVGVIKCIVKDQETSTMLVV Sbjct: 2179 SHTVSTKWYHNKKEISGMDHREIIQEGRIHKLKIKKTKLTDVGVIKCIVKDQETSTMLVV 2238 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR Sbjct: 2239 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 2298 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK Sbjct: 2299 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 2358 Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE Sbjct: 2359 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 2418 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT Sbjct: 2419 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 2478 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 LIIRKCTEDDQCEYTCVLLDAKS+TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ Sbjct: 2479 LIIRKCTEDDQCEYTCVLLDAKSSTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 2538 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE Sbjct: 2539 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 2598 Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN Sbjct: 2599 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 2658 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT Sbjct: 2659 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 2718 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR YKCIA Sbjct: 2719 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRVATLVVTVTETTIGTYKCIA 2778 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK Sbjct: 2779 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 2838 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP Sbjct: 2839 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 2898 Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN Sbjct: 2899 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 2958 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 ENCEYMFRVIAQNPVGFSEALESEPIVIKTAL + IDNESVYITWFPSE Sbjct: 2959 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALGL----------YGIDNESVYITWFPSE 3008 Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 KNGGSPIIDYKVEIKQEGKKWK ARIQKLSINTTYQFRIYARNEIGTSLPYT Sbjct: 3009 KNGGSPIIDYKVEIKQEGKKWKTITTVTETTARIQKLSINTTYQFRIYARNEIGTSLPYT 3068 Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW Sbjct: 3069 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 3128 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA--------- 1963 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA Sbjct: 3129 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAQAYTSQTYL 3188 Query: 1964 ----TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV Sbjct: 3189 FFCSAVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 3248 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG+ PGEQTEV Sbjct: 3249 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGT-----PGEQTEV 3303 Query: 2080 XXXXXXXXXXXXXWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 2130 WLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK Sbjct: 3304 TEPTSFSTQTTTSWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 3354 Score = 694 bits (1714), Expect = 0.0 Identities = 349/407 (85%), Positives = 349/407 (85%) Query: 1 MKPKSNEKEVLSDSSEDKIIPPEEQXXXXXXXXXXXXXXXXXILRKLQIEELESSKPQHP 60 MKPKSNEKEVLSDSSEDKIIPPEEQ ILRKLQIEELESSKPQHP Sbjct: 967 MKPKSNEKEVLSDSSEDKIIPPEEQKSEPKLLLNNKKSKDKPILRKLQIEELESSKPQHP 1026 Query: 61 EEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK 120 EEMTVPQF QEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK Sbjct: 1027 EEMTVPQFSKLKLKKSSVLPKQEPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIK 1086 Query: 121 QNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE 180 QNGELSRNVKEAN DLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE Sbjct: 1087 QNGELSRNVKEANKIKKKKLKLPKIPDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEE 1146 Query: 181 AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM 240 AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM Sbjct: 1147 AKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEM 1206 Query: 241 EVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPL 300 EVSTPQHAETVDGPQF ETSLVKLPKFQLKSRIKYITSWPPESIKPL Sbjct: 1207 EVSTPQHAETVDGPQFTLPKLKKTAVKPKKETSLVKLPKFQLKSRIKYITSWPPESIKPL 1266 Query: 301 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE Sbjct: 1267 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 1326 Query: 361 IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNP 407 IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL P Sbjct: 1327 IIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLKP 1373 >UniRef50_Q17AF2 Cluster: Myosin light chain kinase; n=1; Aedes aegypti|Rep: Myosin light chain kinase - Aedes aegypti (Yellowfever mosquito) Length = 4604 Score = 1868 bits (4632), Expect = 0.0 Identities = 917/1840 (49%), Positives = 1223/1840 (66%), Gaps = 43/1840 (2%) Query: 315 RNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKE 374 + + E +V +V DVE+ E ++ YE+ +++ E+ + +Q LE L Sbjct: 2784 KEVNEDDEVVYEVIYDDSEVDVEEDEYDR----YEE-EDAEHVVLELRKRRQKLESLIVH 2838 Query: 375 DVPE-QYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAET 433 E +T RKS +E T+K++ Y+ E + ++ + AE Sbjct: 2839 QEEEISIDLTRRKSQVTHEEE---SFTLKQQKKSLAT-YSEEEA---NEMYCIQPVEAEN 2891 Query: 434 DEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKID 493 +EAI+LVEGE++Y++D SN +WW+V++ +EE+G+ + LMD Y QY+QK LNEKID Sbjct: 2892 EEAIHLVEGEKVYVIDRSNPEWWFVKRSWSEERGFARRELLMDAVTYPQYVQKTLNEKID 2951 Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 KLP+FEKP E+ AP +EKL+P T DG TVQFEC+VEGYPRPQITWFRQTA+IKPS Sbjct: 2952 KLPIFEKPAPSEKPQAPKIIEKLQPITTQDGYTVQFECKVEGYPRPQITWFRQTAVIKPS 3011 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 QDFQ+YYDDDNVATL+IREVFPEDAGTFTCVAKN AGFASSTTEL V++ SDHGSE+ Sbjct: 3012 QDFQIYYDDDNVATLIIREVFPEDAGTFTCVAKNIAGFASSTTELSVDSFTSDHGSEVAT 3071 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 ADILEGIPPTFS+KPKAQYVD GSD+LLECRLVAIPEPDI W + G E Sbjct: 3072 LSRKSMSRESSLADILEGIPPTFSRKPKAQYVDVGSDVLLECRLVAIPEPDIHWFYNGTE 3131 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 I NI V +ESDMHMYC+V++I N+ K QEG+Y VVA NREGE++L I +K+KTG E Sbjct: 3132 ITTKGNIDVVVESDMHMYCTVVQIRNIDKKQEGSYQVVARNREGESALDITVKVKTGVLE 3191 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PPQ++EPLKSM +RQGE+V+LS Q+VGNP P + W KN + +K PT++D + +++T+L Sbjct: 3192 PPQILEPLKSMSIRQGETVMLSTQIVGNPTPEVQWFKNGEVLKT-PTQADKNMYTVTLLS 3250 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 P ++ G YT+KA+N+ G ET+A +TV+E N + PLF+ RF+E +V + GTIKL Sbjct: 3251 PTH-ENAGEYTVKAKNAAGTVETTAFLTVDESNVGNPQAPLFLERFEEQSVPQGGTIKLP 3309 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 A+V+ NPVP I W RNN + S+ + Q +DG+NIEL I+N DSE DSG+YKC+ASN+ G Sbjct: 3310 AKVSGNPVPEILWLRNNNTLLTSKKVKQAYDGQNIELTISNADSEQDSGNYKCIASNTVG 3369 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973 K+SHGARVT++V++VTFVK L+K+ EE K+V LEC+TSHTVSTKW+HN KE+SGMDHR Sbjct: 3370 KASHGARVTVEVDRVTFVKKLKKTVTVEESKSVTLECETSHTVSTKWFHNGKEMSGMDHR 3429 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 I+QEG+ D G+ +C VKDQ T L V E PEFIRK++D E KEK Sbjct: 3430 VIVQEGKVHKLVIKNPTIKDTGMYQCTVKDQVTECSLTVLEAKPEFIRKMEDVETKEKQN 3489 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 A+LEVEI SETADVVW ++G+ I +K KY+F K+G R L +R+TSVHDEGEY+C L D Sbjct: 3490 AVLEVEITSETADVVWYKEGKKIVEEKGKYEFSKKGKTRSLLVRSTSVHDEGEYTCALAD 3549 Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 + C+AEV V+ELPPEIIT L++ V +G A F+IELTKGDALVRW++D +E+ F+ H Q Sbjct: 3550 QECSAEVVVIELPPEIITPLKDVTVARGENAVFDIELTKGDALVRWYRDDTELSFNGHYQ 3609 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 LTIDGK+Q LKI +DAG Y C VG+ TA LTVE P ++F RLP+ + TD Sbjct: 3610 LTIDGKRQTLKIIKTVDEDAGVYKCVVGDQLSTAKLTVERPLVDFVKRLPDVTIATKQTD 3669 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 A VE+ E+ +VTWYK I+ + K+ LI+D K R LI++ TEDD+ EYTC + + Sbjct: 3670 AVFVVEL-SESAEVTWYKNSKKIKASSKYELIADKKVRKLIVKNVTEDDEDEYTCTIANV 3728 Query: 1274 KSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 K+++KLKVEV++ P I D R Y I++ DVT V + A P+P+ EW VN K++ Sbjct: 3729 KTSSKLKVEVIKVAPTIFDDGSRTYTIRKEDDVTFNVKFNATPKPDSEWYVNEKLVIPSP 3788 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 P+I ++ASLTIKKV +DAG Y +RL N CG A + + +P P P +I Sbjct: 3789 RFVPTIGEETASLTIKKVVESDAGDYTVRLVNECGDASASFTLIVKRQPGAPDAPEATQI 3848 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 SI + W PE+ GNSTI Y++EYQE +W + NI++T T++ L NS Y FR Sbjct: 3849 TDDSITLFWKSPEDNGNSTITEYILEYQEKSKKKWTEITNISETTTTVTKLTKNSEYTFR 3908 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 AVNE+ AS + YYK+ K ++P V + LK++ ++ I LTCI GVP P+ Sbjct: 3909 VTAVNEMGKGPASPNSPYYKIAAPIKKEAPVVSEHLKDVHIGLDQTITLTCIVNGVPTPE 3968 Query: 1513 VTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 V+WYR+G LK TYEN Y C A N+ G VE+SC V I++KP Sbjct: 3969 VSWYRNGTALKEKTITYENGAAKYVIVKTTKETSGTYVCKAVNEVGSVESSCKVVIEEKP 4028 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 IT+ + I QK +VGDEW V A EG P PE++WY+ +E+ E+ I T K+S I Sbjct: 4029 TITVDKKQIVQKLRVGDEWTVVANFEGYPVPEIVWYREDEVIESTAEHTIVTISKSSTIV 4088 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 I +L RS S KY +EA N+AG++SVE+ LKV DKPSKPEGP+I++E+S E+V IEWKPP Sbjct: 4089 IGKLDRSDSGKYVVEARNSAGSASVELQLKVIDKPSKPEGPIIVKELSPEAVVIEWKPPA 4148 Query: 1692 DDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 DDGGLE+++Y+IEK + N N WIKVADV +++++YCIQKL ++ +Y FRVIAQNP+G S Sbjct: 4149 DDGGLEISQYSIEKCDDTNKNAWIKVADVQKNIKSYCIQKLLDSTQYHFRVIAQNPIGCS 4208 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 E LES I +K L+ PS + + S ++W PSE NGGS I +Y VE+K+ Sbjct: 4209 EPLESATITVKQVLEPPSPPRGPIETSGMTSHSFTLSWQPSEHNGGSKITEYIVEMKESK 4268 Query: 1811 KK-WK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 KK WK I+ LS N Y FRI+A+N+IGTS +++ I GK +TPPS Sbjct: 4269 KKVWKVVGSTSASETSLLIENLSANRGYDFRIFAKNKIGTSEALQTEESIVAGKEITPPS 4328 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 PRN + TS+S+ L+W +PE+NGGS +T Y+IE + + WTKI T+ + +C+ Sbjct: 4329 APRNLRIVNVTSKSIKLEWQQPETNGGSDVTGYVIEKRLTTSQQWTKIKTLDATCLSYCV 4388 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-----------------TVPSPPT 1970 +N+KEK E++FR+ AEN +G+S P S++V L+ +A VPSPPT Sbjct: 4389 DNLKEKSELVFRVFAENVIGLSPPATSETVTLKSYAKISEKWLTIRIAFFFTTAVPSPPT 4448 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 PLE+R +G NI + WG PE DGGAPL GYNI IR++ KTMWMEVG+V + FNI+D Sbjct: 4449 GPLEVRYLGPNINIVEWGIPESDGGAPLEGYNIVIRNIKKTMWMEVGRVSADCQSFNIKD 4508 Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXX 2090 L+E+ Y+IRI ARNE+G S+PLES+EP+K G A E+ ++T Sbjct: 4509 LAEDEEYLIRIIARNEVGNSDPLESEEPYKAQLGA---APEDTHDET-TRDFTEPSATNT 4564 Query: 2091 XXWLREHNMDADIRSYARGSLLRRDEYFFRIWHYAKQLFK 2130 WLREHNM ADI SYAR LLRR EYFF++W AK LFK Sbjct: 4565 SSWLREHNMTADIHSYARHKLLRRREYFFKLWVNAKNLFK 4604 Score = 77.0 bits (181), Expect = 5e-12 Identities = 71/248 (28%), Positives = 115/248 (46%), Gaps = 13/248 (5%) Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219 D E E + ++ + P+ I ++ K E ++ + + ++ E + + + E Sbjct: 311 DHTEQEERTEIKKTPKKIKKKIKKSGP--SEEDEALERLLNLEVEKTQ-LEEYEKIELEA 367 Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPK 279 P + KL PI+IERKE + + Q ET D PQ E V +PK Sbjct: 368 KPKLEKPKPKLEPIRIERKEQKATKLQITETEDQPQMIKLKKVKVPGKKEIEE--VVVPK 425 Query: 280 FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKT 339 LKSR+ + +PP P IS + + K G L+R +E K+K + K +K Sbjct: 426 VLLKSRMMMV-QYPPAVQYPQISTIVTKKGIGELARVNEEEEKIKLKKIKKIKTTKRDKL 484 Query: 340 ELEQ-PLFSYEDIV---ESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEI 395 ELEQ L YE+ V E K +E E Q KQ E++ +E P+ T+ K +K + + Sbjct: 485 ELEQVDLPEYEEEVSEEEQKPEEKEKYQRKQK-EKVDEE--PQVKTLKLGKGIVKKDEPV 541 Query: 396 VDEVTIKK 403 + +T+KK Sbjct: 542 EETITLKK 549 Score = 72.5 bits (170), Expect = 1e-10 Identities = 55/180 (30%), Positives = 93/180 (51%), Gaps = 13/180 (7%) Query: 229 KLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKY 288 KL PIKIERKE + P E D P+ E V +PK LKSR+ Sbjct: 1588 KLEPIKIERKEQK---PTKLEITDTPEPQTVKLRKTVIPEKKEIEEVTVPKVLLKSRVVQ 1644 Query: 289 ITSWPPESIKPLISYMGSIKQNGILSR-----NIKEAAKVKKQVFVPPKLPDVEKTELEQ 343 + +PPE+ KP I + + + G LSR + ++ K+KK + + P++E ++E+ Sbjct: 1645 V-EYPPEAQKPKIVQLETKQGVGELSRIEEEEDERKVKKIKKVKVIKKEKPELEVLDIEK 1703 Query: 344 PLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKK 403 F E V+ +K+E + ++Q ++E P E+ E+ T+ K +K ++ ++EV +KK Sbjct: 1704 --FEKEPTVQEEKEEEKPKYQRQ-IKEKPVEET-EERTLVLGKGKLKKEEDEIEEVKLKK 1759 Score = 44.4 bits (100), Expect = 0.035 Identities = 51/216 (23%), Positives = 84/216 (38%), Gaps = 11/216 (5%) Query: 44 LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRD 103 L ++IE E KP E P+ +E V +PK LKSR+ + + Sbjct: 1589 LEPIKIERKEQ-KPTKLEITDTPEPQTVKLRKTVIPEKKEIEEVTVPKVLLKSRVVQV-E 1646 Query: 104 WPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDL----- 158 +PP+ KP + L + + GELSR +E + E+ LE D+ Sbjct: 1647 YPPEAQKPKIVQLETKQGVGELSRIEEEEDERKVKKIKKVKVIKKEKPELEVLDIEKFEK 1706 Query: 159 ---FDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV-PDD 214 +++E KP + + E E L+ + + EI+ +K V P + Sbjct: 1707 EPTVQEEKEEEKPKYQRQIKEKPVEETEERTLVLGKGKLKKEEDEIEEVKLKKTPVRPKE 1766 Query: 215 KETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAET 250 +E + K K T +I +K+ V P T Sbjct: 1767 EEEVEAVIKKKKEEKPTEDEIIKKQKHVEKPTFTPT 1802 Score = 43.6 bits (98), Expect = 0.061 Identities = 49/214 (22%), Positives = 91/214 (42%), Gaps = 12/214 (5%) Query: 46 KLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIRDWP 105 +++ +E +++K Q E PQ E VV PK LKSR+ ++ +P Sbjct: 382 RIERKEQKATKLQITETEDQPQMIKLKKVKVPGKKEIEEVVV--PKVLLKSRMMMVQ-YP 438 Query: 106 PQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLFDSQ--- 162 P P ++ + + K GEL+R +E +++ LE+ DL + + Sbjct: 439 PAVQYPQISTIVTKKGIGELARVNEEEEKIKLKKIKKIKTTKRDKLELEQVDLPEYEEEV 498 Query: 163 -EDESKPDVSQPPQ-NIIEEAKSEP--KLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218 E+E KP+ + Q E+ EP K ++ + + K ++ + K KE Sbjct: 499 SEEEQKPEEKEKYQRKQKEKVDEEPQVKTLKLGKGIVKKDEPVEETITLKKTPKKPKEDV 558 Query: 219 QTPTSFNKRSKLTP--IKIERKEMEVSTPQHAET 250 + T+ K+ K P I+ +++ V P + T Sbjct: 559 EAETTSVKKPKQKPELIEHDKEHKHVQKPTFSPT 592 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/75 (32%), Positives = 42/75 (56%), Gaps = 5/75 (6%) Query: 335 DVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTIT--PRKSSAQKI 392 +VEKTELEQ + D+ K+++ +I Q+ Q ++ + + E+ TI PRK S + Sbjct: 2468 EVEKTELEQ--YEKVDVDFKKREKLKITQQPQP-QQAVESTIEEEQTIQLKPRKKSVKPS 2524 Query: 393 DEIVDEVTIKKRLNP 407 E ++E + +L P Sbjct: 2525 VETIEETEVAFKLKP 2539 Score = 37.5 bits (83), Expect = 4.0 Identities = 49/207 (23%), Positives = 86/207 (41%), Gaps = 13/207 (6%) Query: 203 NEVPEKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVST----PQHAETVDGPQFXX 258 NE EKI + K+ + T+ + +L + + E EVS P+ E Q Sbjct: 462 NEEEEKIKL---KKIKKIKTTKRDKLELEQVDLPEYEEEVSEEEQKPEEKEKYQRKQKEK 518 Query: 259 XXXXXXXXXXXXETSLVKLPK-FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNI 317 +VK + + +K P E ++ + + KQ L + Sbjct: 519 VDEEPQVKTLKLGKGIVKKDEPVEETITLKKTPKKPKEDVEAETTSVKKPKQKPELIEHD 578 Query: 318 KEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKED-V 376 KE V+K F P ++PDVE ELE+ + + ++E +++ + PKED V Sbjct: 579 KEHKHVQKPTFSPTEIPDVE-VELEE-YRQPSPVPDVPEEETPHKKKRSKKPKEPKEDEV 636 Query: 377 PEQYTITPRKSSAQKIDEIVDEVTIKK 403 PE+ I + ++I E ++V +K Sbjct: 637 PERPLIMGKGKKPEEIPE--EDVKFRK 661 Score = 36.7 bits (81), Expect = 7.0 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 2/71 (2%) Query: 335 DVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDE 394 ++EKTELE+ +IV+ K EI+ E++ EE EDVPE+ P K + I Sbjct: 2218 EIEKTELEKYEKVDIEIVKKPKTVEEIVVEQKP-EEPKVEDVPEEVVFKP-KPKDRVIKP 2275 Query: 395 IVDEVTIKKRL 405 + +EV + +L Sbjct: 2276 VEEEVEVDFKL 2286 >UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - Drosophila melanogaster (Fruit fly) Length = 18074 Score = 1773 bits (4397), Expect = 0.0 Identities = 859/1864 (46%), Positives = 1210/1864 (64%), Gaps = 57/1864 (3%) Query: 301 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360 IS G +K + + EAA K + + D E+ +E+ + ED ++ ++ E Sbjct: 16213 ISMSGKVKLKKPIKKTFSEAADEAK-IKIIQDFDDGEEPIIEE-IRDDEDTIDEVEEPEE 16270 Query: 361 IIQEKQTLEEL---------PK------EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL 405 E+ +E+ PK ++ EQ+ I R + D +T KK+ Sbjct: 16271 YFVEELPPDEVDFKLKPKKHPKPAYSVQDEEEEQFLIGIRHPKRDSVTYDEDSLTFKKKR 16330 Query: 406 NPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEE 465 + + E + ++++ +Y+A+ +EAINLVEGE++ ++ + +WWYV+K TEE Sbjct: 16331 KVVQQLFNE-ESENLNIMYSICNYIADNNEAINLVEGEKVTVVGRHSSEWWYVKKSTTEE 16389 Query: 466 KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS 525 +GWVPAQYLM+ Y QY+Q KL+EKIDKLPVFE+P E++ +AP F+EKL+P HTPDG Sbjct: 16390 EGWVPAQYLMEPEEYAQYVQNKLHEKIDKLPVFERPGPEDKPIAPRFIEKLQPIHTPDGY 16449 Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 TVQFEC+VEG PRPQI WFR+TAIIKPSQDFQM+YDDDNVATL+IREVFPEDAG FT VA Sbjct: 16450 TVQFECKVEGNPRPQIAWFRETAIIKPSQDFQMFYDDDNVATLIIREVFPEDAGQFTVVA 16509 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 KNAAGF SSTTELIVE+PLSDHGS+ T ADILEGIPPTFSKKPKAQYV Sbjct: 16510 KNAAGFTSSTTELIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQYV 16569 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIESDMHMYCSVLKITNVKKF 703 DE ++++LECRLVA+PEPDI W F GE+I +E N+ + ESDMHMYCSV+ I+ VKK Sbjct: 16570 DENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKS 16629 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 QEGTY V+A NREGEA LPI LK++T +KE PQ++EPL++M++R+GESV+LS Q+VGNP Sbjct: 16630 QEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPP 16689 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P +TW K+ KPVK KSD D H++T++ P+K ++G YT+KA N G ET+A +T+E Sbjct: 16690 PKVTWYKDGKPVKN--AKSDKDLHTLTLITPQK-SEKGEYTVKAVNPLGSVETTANLTIE 16746 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 EP NAEPPLF+ RF+E V +KG I+L A+V+ NPVP + W NN + PSE I Q + Sbjct: 16747 EPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVY 16806 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 DGENIEL+I + + E DSGDYKC+ASN GK+SHGARV ++V++VTF K L+K+ EE Sbjct: 16807 DGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTFTKKLKKTITIEEV 16866 Query: 944 KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 +++ LEC+TSH V+TKW+ N KE+SGMDHR ++++G+ D G C VK Sbjct: 16867 QSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKK 16926 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 QET + + V + P+FI+ L+D+EV EKD AIL+VE+ +E +V W +DGE I P+ Sbjct: 16927 QETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTEATEVTWYKDGEKITPENKNV 16986 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 +F K G R+L IR+ ++HDEG+Y+C + + C+ E+ V+ELPPEI+ L + V KG Sbjct: 16987 EFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVVIELPPEIVEPLNDVAVTKGEN 17046 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 A FE+EL+KGDALV+WFK+G EI F+ IQL IDGKKQ L+I +D GEYS +VG Sbjct: 17047 AVFEVELSKGDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVGEQ 17106 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 A LTVEEP ++F +RLP+ L TDA TV++ ++VTW KK I+ +K Sbjct: 17107 TSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQKHE 17166 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRG 1302 + + R L+I +++D E +CV + S+TKL VE ++ PP I D ++ ++K Sbjct: 17167 VFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKEN 17226 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 DVT V Y P P W +I K K T P+ID +SA LTIKKV + D G Y ++L Sbjct: 17227 DDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKVVDDDEGEYTVKL 17286 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 N G A+ +++ I+ KP+ PG P LEI SI + W PE+ G S II Y++EYQ++ Sbjct: 17287 VNPVGEAEASLHLVIMRKPTAPGTPQPLEIMHDSITLYWKAPEDDGKSEIIEYILEYQDV 17346 Query: 1423 DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 +W ++ I T +I LK ++ Y FR+ AVNEV S S + +++ + + ++P Sbjct: 17347 KEEKWTEIRKIKDTTYTISKLKIDTEYVFRSIAVNEVGPSPPSPLSPPIRLVPKVETKAP 17406 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR-XXXXXXXXX 1541 +V++PL+++ +E ++++ L+C+FGG+P+PKVTW ++G+ ++ YENR Sbjct: 17407 SVQEPLQDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYTIEKTT 17466 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+A N+ G ETSC + +QQKPV+ + ++ + QK + G + A + G P Sbjct: 17467 IETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQ 17526 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P V W+K + + K I T E TS +K++ R S KY + A+N +GT+ VE T++ Sbjct: 17527 PTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQ 17586 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 V DKPS+P+ + +++I ++S+ +EW PP+DDGGL++ KY +EK + NN W+KV+D ++ Sbjct: 17587 VIDKPSRPQS-LEIKDIKKDSIVLEWTPPVDDGGLDIEKYTLEKCDVQNNVWMKVSDFNK 17645 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 D+++Y +QKL+ N +YMFRV+A NP+G SE ES+P+ I + PS +++ Sbjct: 17646 DIKSYAVQKLSMNAQYMFRVVAANPIGESEPTESDPVTITKKFEKPSPPRGPTTVSGMND 17705 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKLSINTTYQFR 1838 S + W PSE +GGS II+Y VEI++E + + ++K+ N Y FR Sbjct: 17706 TSFNLAWEPSETDGGSKIIEYIVEIREETETTYRSVGVTLGTVTNIHVEKVVRNKGYFFR 17765 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 IYARNE+GTS + + +KI +G+ +TPPS P+N + TSRSVTL W P NGGS IT Sbjct: 17766 IYARNEVGTSEAFETTEKIVLGRKITPPSPPQNLRAPDVTSRSVTLDWEVPARNGGSEIT 17825 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 Y +E ++ +WTK++T+ + I+N+KEK E FR+SAEN VG+ P ++S+ Sbjct: 17826 GYCVEKRSSTSTNWTKVITLDAHQLHYTIDNLKEKCEYWFRVSAENEVGLGAPAVTESIS 17885 Query: 1959 LEKHAT--------------------VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 L+ HA+ VPSPPT PLE R++ +N + WG PE DGGAPL Sbjct: 17886 LKTHASEFILVVRNCGSYTEFGFLKAVPSPPTGPLEARVLAANAHIFEWGLPESDGGAPL 17945 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 LGY+IAIRD+ KTMW+EVG+V LKF IRDL ENH YMIRI+A+NEIGLSEPLES+EP Sbjct: 17946 LGYHIAIRDMKKTMWIEVGRVPAGVLKFQIRDLQENHEYMIRIFAKNEIGLSEPLESEEP 18005 Query: 2059 FKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREHNMDADIRSYARGSLLRRDEYF 2118 +K + +EP +TE+ WLR+H+MDADI SYARG LL+RDEYF Sbjct: 18006 YKAMTAGHESLPDEP--RTEM------SSCNTSSWLRDHHMDADIHSYARGRLLQRDEYF 18057 Query: 2119 FRIW 2122 FR+W Sbjct: 18058 FRLW 18061 Score = 167 bits (406), Expect = 3e-39 Identities = 166/678 (24%), Positives = 295/678 (43%), Gaps = 68/678 (10%) Query: 335 DVEKTELEQPLFSYEDIV--ESKKDENEIIQEKQT--LEELPKEDVPEQYTITPRKSSAQ 390 DV+ + + + E++V E + + +K+T L+E E P+ + + + Sbjct: 6351 DVKVVAVSEDVLPEEEVVPTEETPEAKQKAHKKRTKRLKEASVEGQPQ--LLEAAIAEIE 6408 Query: 391 KIDEIVDEV-----TIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGE-R 444 K+DEI E+ T+ K+ + E V V + E N+++ E R Sbjct: 6409 KVDEISQEISQKTITLLKKTEDTRPQFITTEQLIELDVEDVRRDL-EMKVTSNIIKKEKR 6467 Query: 445 LYILDTSN---QDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKP 501 +LD S + QK + E V + L+++ Q Q+ ++ Sbjct: 6468 RVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLIQNQQETTTSEVIGQERKLVK 6527 Query: 502 TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 +++ P EKLRP+ P+ TV EC+VEG P P+I W+ ++ S+ +++ Sbjct: 6528 KKKKEIKPPRITEKLRPRQCVPEEPTV-LECKVEGVPFPEIKWYFNDILLFASEKYEITV 6586 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620 + VA L I +V P D G +TC AKN AG A+S T +I+E + G Sbjct: 6587 MEQ-VAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIILE---KEQG------------ 6630 Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGS----DILLECRLVAIPEPDIAWLFKGEEIVP 676 +PP F+K K ++++E + + C++ P P++ W EE++P Sbjct: 6631 -----------VPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIP 6679 Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE- 733 E + + D L++ N + Y+V A N+ G A + I+ ++ +E Sbjct: 6680 SETVQMFY--DEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI 6737 Query: 734 -PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 + PL +++V G ++ A+ G PRP + W +N + + T + T + Sbjct: 6738 LKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTI 6797 Query: 793 KPKKV--KDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 K + K G Y + A+N G A++S +V+ ++ +E +PP FI + E Sbjct: 6798 KVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEV 6857 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + A V P+ S W+ +NE I S + L+I N S+ G + C A Sbjct: 6858 AIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKF-VGPFTCRAE 6916 Query: 910 NSAGKSSHGARVTI-------DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKW 960 N G + A V + + E FV+ L + E +G+ ++L CQ + T +W Sbjct: 6917 NVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEW 6976 Query: 961 YHNKKEISGMDHREIIQE 978 YHN ++I+ I Q+ Sbjct: 6977 YHNAEKITENKETTISQD 6994 Score = 149 bits (361), Expect = 8e-34 Identities = 116/436 (26%), Positives = 192/436 (44%), Gaps = 45/436 (10%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F +K++P + +FE + EG P P + W+R++ I+ S D Q++ + L Sbjct: 4393 APVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGK-SIL 4451 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXAD 627 +IR+VF ED+ F+CVA+N G A + L+V E + G Sbjct: 4452 IIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQ---------------- 4495 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 PP+F ++ V G + ++ D+ WL G +I P + E Sbjct: 4496 -----PPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDS 4550 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----------GEKEPPQV 737 +H L I G Y VAVN GEA +++ G ++ P + Sbjct: 4551 VH----TLLIIEPFAEDSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHI 4606 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794 +E LKS V +G VI +V G P PT W + KP + G+ + + ++ Sbjct: 4607 VEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQMSRQGEYYQL-VISE 4665 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 +DEG Y AEN G +TSA + V P EN + P I ++++V E + Sbjct: 4666 AFPEDEGTYKCVAENKLGSIQTSAQLKV-RPI-ENLDAPPTITALKDVSVTEGMPAQFKT 4723 Query: 855 RVT-RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 VT + S+ W+R ++I + FDG + L+I E DSG + ++S G Sbjct: 4724 TVTGKVKATSVQWFREGQLIPETPDFQMIFDGNSAVLLIGTTYEE-DSGIFTVRVTSSTG 4782 Query: 914 KSSHGARVTIDVEKVT 929 + A++T+ +++ Sbjct: 4783 QVESSAKLTVKKRRIS 4798 Score = 144 bits (350), Expect = 2e-32 Identities = 124/436 (28%), Positives = 201/436 (46%), Gaps = 45/436 (10%) Query: 504 EEQSMAPIFVEKLR----PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 +EQ + P F + L+ + P+ V CQV G P P++ W+R + PS+ QM+ Sbjct: 6627 KEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMF 6686 Query: 560 YDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617 YD+ +VA VI P +A ++ A+N G A ++ E+ Sbjct: 6687 YDEKTGDVALEVINPT-PNEAVVYSVQAQNQFGRAIGNANILSRV------DEVP----- 6734 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 +IL+ PT + A V G + E + +P P++ W+ G EI+ Sbjct: 6735 --------REILKA--PTVTPL-SAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREII-- 6781 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEK-E 733 EN IE+ + +K+ N+ + + G Y V A N+ GEA +V K E+ + Sbjct: 6782 ENEETIIETTETT--TTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIK 6839 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITIL 792 PP+ I+PL+ + E I+ A V P + W +N+P+K+ + + T+L Sbjct: 6840 PPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLL 6899 Query: 793 KPK-KVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGT 849 + K G +T +AEN G + T+ V + + E E P F+ Q + V + Sbjct: 6900 IENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEA 6959 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCV 907 + L +VT P P + WY N E I+ ++ TI+Q+ G +L IT V E + G Y+CV Sbjct: 6960 LLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGV-CQLQITEVFPE-NEGQYECV 7017 Query: 908 ASNSAGKSSHGARVTI 923 A+N GKS V I Sbjct: 7018 ATNKIGKSVSKTNVKI 7033 Score = 140 bits (339), Expect = 4e-31 Identities = 97/359 (27%), Positives = 162/359 (45%), Gaps = 15/359 (4%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L+ E ++ + + ++ + D E ++ + AP +K R +GS F +V Sbjct: 219 LLREVSFREAITRRSGYEQDSQLSQELDRNQGPAQAPQISQKPRSSKLIEGSDAVFTARV 278 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 P+P++TWF + SQ +++ Y VATL ++ D G +T +A+N G Sbjct: 279 GSNPKPRLTWFHNGQRLVASQKYEISYSS-GVATLRVKNATARDGGHYTLLAENLQGCVV 337 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653 S+ L VE P ++ E A +PP F K + + EG Sbjct: 338 SSAVLAVE-PAAETAYEPKPVDVMAEQLEAGKA-----LPPAFVKAFGDREITEGRMTRF 391 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVA 712 +CR+ P P++ WL G ++ D + + + ES H L ITNV + G +A Sbjct: 392 DCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHS----LMITNVTRLDAGAVQCLA 447 Query: 713 VNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 N+ GE ++ L + E+ PQ ++ +M VR+GE + +SA +G P+P ITW K+ Sbjct: 448 RNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKD 507 Query: 772 NKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + + + G T L+ +V D G Y A+N G A + VE P E+ Sbjct: 508 GVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQ 566 Score = 115 bits (276), Expect = 2e-23 Identities = 119/528 (22%), Positives = 215/528 (40%), Gaps = 43/528 (8%) Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 ELI + L + E T E PP ++K + + +LEC+ Sbjct: 6499 ELIEDQQLIQNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECK 6558 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + +P P+I W F + E + + + + LKI V G YT A N Sbjct: 6559 VEGVPFPEIKWYFNDILLFASEKYEITVMEQV----AKLKIAKVTPSDVGVYTCEAKNEA 6614 Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----SVILSAQVVGNPRPTITWCKN- 771 G A+ + ++ + PPQ +PLK + + + V ++ QV G P P + W + Sbjct: 6615 GVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGI 6674 Query: 772 -----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEE 824 ++ V+ + GD ++ ++ P + VY+++A+N G I + + V+E Sbjct: 6675 EEVIPSETVQMFYDEKTGDV-ALEVINPTP-NEAVVYSVQAQNQFGRAIGNANILSRVDE 6732 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNF 883 E + P + + V GT+ A+ P P + W RN EII ETI + Sbjct: 6733 VPREILKAPT-VTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETT 6791 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTID------VEKVTFVKHLQK 936 + + + N+ + +G Y+ A N G++ S G+ V D ++ F++ L+ Sbjct: 6792 E-TTTTIKVVNMTRK-RTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEP 6849 Query: 937 SYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 Y E +I S +S+ +W+ + + I + I+ + VG Sbjct: 6850 KYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVG 6909 Query: 996 VIKCIVKD---QETSTM---LVVKETI-----PEFIRKL-QDFEVKEKDVAILEVEINSE 1043 C ++ TST L+ +E P F+ +L Q EV + + +L ++ + Sbjct: 6910 PFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGK 6969 Query: 1044 -TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 T V W + E I K + + +L I +EG+Y C+ Sbjct: 6970 PTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECV 7017 Score = 109 bits (263), Expect = 6e-22 Identities = 81/318 (25%), Positives = 140/318 (44%), Gaps = 32/318 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P S+KP++ + EGSD + R+ + P+P + W G+ +V + ++ S + + Sbjct: 255 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGV----A 310 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVL--------------------KIKTGEKE 733 L++ N G YT++A N +G VL +++ G+ Sbjct: 311 TLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKAL 370 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSI 789 PP ++ + +G +V GNP P + W N + V+ + ++ +HS+ Sbjct: 371 PPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSL 430 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 I ++ D G A N G A + V E +E P F+ RF +TV+E Sbjct: 431 MITNVTRL-DAGAVQCLARNKAGEVAIEAQLNVLE--KEQVVAPQFVQRFSTMTVREGEP 487 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 I + A P P ITW ++ IS + DG L I V + D+G Y+C A Sbjct: 488 ITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTAN-DAGWYQCTAQ 546 Query: 910 NSAGKSSHGARVTIDVEK 927 N AG +++ AR+ ++V + Sbjct: 547 NIAGSTANRARLYVEVPR 564 Score = 109 bits (262), Expect = 8e-22 Identities = 153/648 (23%), Positives = 251/648 (38%), Gaps = 98/648 (15%) Query: 480 YTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538 Y + + K+ E K V +EQ P F++ L PK+ + E VE P Sbjct: 6810 YEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPL 6869 Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598 WF IK S + ++ N +TL+I + G FTC A+N G +ST + Sbjct: 6870 SSFQWFVHNEPIKSSNEVRIV-SQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATV 6928 Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 + P + A+ E P + + V +G +LL C++ Sbjct: 6929 NL-IPQEE-------------------AEEFES-PRFVEELVQPVEVMDGEALLLTCQVT 6967 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 P P + W E+I EN I D+ C L+IT V EG Y VA N+ G+ Sbjct: 6968 GKPTPKVEWYHNAEKIT--ENKETTISQDLQGVCQ-LQITEVFPENEGQYECVATNKIGK 7024 Query: 719 ASLPIVLKIK-------------TGEKEP------------PQVIEPLKSMIV-RQGESV 752 + +KI+ TG +E P++I+ L I ++GE Sbjct: 7025 SVSKTNVKIQAFEYIPDSEITGLTGSEEDLLDRTLSIDEQAPKIIKKLPEKIEPKEGEQA 7084 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L +VVG P+P + W ++++ + A ++ D S+ ++ D G + +A N Sbjct: 7085 KLEVKVVGKPKPKVKWLRDDEQIFASEEYQIENFEDGTSVLVINHVYPDDLGTISFEAYN 7144 Query: 810 SEGIAETSAVITVEEPT-EENAEPPLFINRFQEITVKEKG-------------------- 848 G+A T+A+ VE ++ P ++++ +E+ V K Sbjct: 7145 PLGVAVTTALFAVEGIVGSKDYRKPEWVSQMEEMQVALKAAKCSPSLLNEMRDCRAALGE 7204 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 T K + NP+P I WY NN + SE + L I + SE D G Y C Sbjct: 7205 TAKFSIQFAGNPIPDIQWYFNNVQLRASEKYRMVVQEQEATLEIMKITSE-DCGYYNCKL 7263 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 N G + R D+ + + E + KT + + T+ + ++ + Sbjct: 7264 INEIGMTM--TRAKFDISSTSTI------VEETKAKTTVKKKSGKKTMVKRSGASESQNV 7315 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028 II V V +V+ E S +LVVK+ R++ D E Sbjct: 7316 QKTEIRIIPTSAVETSMNVIKVKQPVSV---LVEKSEISEVLVVKD------REVADAEE 7366 Query: 1029 KEKDVAILEVEINSETADVVW---ERDGEIIKPKKNKYDFEKRGHIRK 1073 + + I E+E E + V E + E+ +K Y K+ I K Sbjct: 7367 RSSQL-IEEIEEEEEIEEKVQHDEEDEVEVQVEQKETYTSSKKIEITK 7413 Score = 101 bits (243), Expect = 2e-19 Identities = 100/395 (25%), Positives = 162/395 (41%), Gaps = 33/395 (8%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITIL 792 P + ++ V + E + G P PT+ W + + P++ P SI I+ Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 4453 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEE---PTEENAEPPLFINRFQEITVKEKGT 849 + V+D V++ AEN G A+ SA + VEE + +PP F+ Q TV Sbjct: 4454 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 4513 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + A+VT + W +N I PS + L+I +E DSG Y+CVA Sbjct: 4514 ARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE-DSGRYECVAV 4572 Query: 910 NSAGK------------SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHT 955 N+AG+ S T EK + KS EEG VI C+ T Sbjct: 4573 NAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPT 4632 Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLV 1011 + +W + + + ++ ++G D G KC+ +++ +TS L Sbjct: 4633 PTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLK 4692 Query: 1012 VK--ETI--PEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPKKNKYDF 1065 V+ E + P I L+D V E A + + + V W R+G++I P+ + Sbjct: 4693 VRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLI-PETPDFQM 4751 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 G+ L I T D G ++ +R S T +V Sbjct: 4752 IFDGNSAVLLIGTTYEEDSGIFT--VRVTSSTGQV 4784 Score = 100 bits (239), Expect = 5e-19 Identities = 92/367 (25%), Positives = 160/367 (43%), Gaps = 36/367 (9%) Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQ-----EGTYTVVAVNREG---EASLPIVLKI 727 P +N+ I S+ + Y S+ + V F+ E ++ R G ++ L L Sbjct: 188 PIQNLEKNIYSNGYSYTSIEEEFRVDTFEYRLLREVSFREAITRRSGYEQDSQLSQELDR 247 Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787 G + PQ+ + +S + +G + +A+V NP+P +TW N + + A + Sbjct: 248 NQGPAQAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSS 307 Query: 788 SITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE---------EPTEENAE----- 831 + L+ K +D G YTL AEN +G +SAV+ VE +P + AE Sbjct: 308 GVATLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAG 367 Query: 832 ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGE 886 PP F+ F + + E + RVT NP P + W N + S I N G Sbjct: 368 KALPPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGS 427 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQK--SYETEEG 943 + L+ITNV + +D+G +C+A N AG+ + A++ + + E+V + +Q+ + EG Sbjct: 428 H-SLMITNV-TRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 485 Query: 944 KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 + + + T + W + +IS R + +G D G +C Sbjct: 486 EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 545 Query: 1002 KDQETST 1008 ++ ST Sbjct: 546 QNIAGST 552 Score = 97.9 bits (233), Expect = 3e-18 Identities = 100/423 (23%), Positives = 160/423 (37%), Gaps = 30/423 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+KK + V E E P P + W E P +N S ++ S Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWY---RESFPIQN-SPDLQIHTFSGKS 4449 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT------GEKEPPQVIEPLKSMIVR 747 +L I V ++ VA NR G A L ++ G +PP + ++S V Sbjct: 4450 ILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVA 4509 Query: 748 QGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 G+ A+V G + W KN +P + H++ I++P +D G Y Sbjct: 4510 TGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEP-FAEDSGRYE 4568 Query: 805 LKAENSEGIAETSAVITV------EEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVT 857 A N+ G A V E+PT +E P + + + TV+E + RV Sbjct: 4569 CVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVD 4628 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P+ W R + PS + GE +LVI+ E D G YKCVA N G Sbjct: 4629 GKPTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPE-DEGTYKCVAENKLGSIQT 4687 Query: 918 GARVTI-DVEKVTFVKHLQ--KSYETEEGKTVILECQTSHTV---STKWYHNKKEISGMD 971 A++ + +E + + K EG + + V S +W+ + I Sbjct: 4688 SAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLIPETP 4747 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 ++I +G D G+ V K T+ + R++ F+++ Sbjct: 4748 DFQMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVKK--RRISAFQLRTI 4805 Query: 1032 DVA 1034 D A Sbjct: 4806 DSA 4808 Score = 88.2 bits (209), Expect = 2e-15 Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 12/178 (6%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 EKPT+ AP VE+L+ + +GS V F C+V+G P P W R +KPS+ FQM Sbjct: 4593 EKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQM 4652 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618 + LVI E FPED GT+ CVA+N G ++ +L V P+ + + T+ Sbjct: 4653 SRQGE-YYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVR-PIENLDAPPTI----- 4705 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE-PDIAWLFKGEEIV 675 + EG+P F + E +L IPE PD +F G V Sbjct: 4706 --TALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQL--IPETPDFQMIFDGNSAV 4759 Score = 82.2 bits (194), Expect = 1e-13 Identities = 111/482 (23%), Positives = 194/482 (40%), Gaps = 58/482 (12%) Query: 774 PVKALPTKSDGDTHS--ITILKPKKVKDEGVYTLKAENSEGIAETSAVI---TVEEPTEE 828 P K + S+ H + + K ++V+ E L+ ET+ V T++E + Sbjct: 4326 PPKGIAQPSESSVHGREVHMNKQQQVQKEIQGDLEITRKITATETTEVEHKGTIQERVVQ 4385 Query: 829 N----AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNF 883 A+ P+F + Q V E K P P++ WYR + I S + F Sbjct: 4386 GPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTF 4445 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHL 934 G++I L+I V E DS + CVA N G + A + ++ ++ +FV + Sbjct: 4446 SGKSI-LIIRQVFVE-DSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTI 4503 Query: 935 QKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 Q S G+ + + + T + W N +I ++++E Sbjct: 4504 Q-STTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE 4562 Query: 993 DVGVIKCIVKDQETSTML----VVK-------------ETIPEFIRKLQDFEVKEKDVAI 1035 D G +C+ + +V+ E P + +L+ V+E I Sbjct: 4563 DSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVI 4622 Query: 1036 LEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 ++ + T W R +KP + + ++G +L I DEG Y C+ ++ Sbjct: 4623 FRCRVDGKPTPTARWMRGENFVKPSRY-FQMSRQGEYYQLVISEAFPEDEGTYKCVAENK 4681 Query: 1095 ------SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELT-KGDAL-VRWFKDGS 1144 S +V +E P IT L++ V +G A F+ +T K A V+WF++G Sbjct: 4682 LGSIQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQ 4741 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSIN-FT 1199 I + Q+ DG L I +D+G ++ V G + +A LTV++ I+ F Sbjct: 4742 LIPETPDFQMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVKKRRISAFQ 4801 Query: 1200 LR 1201 LR Sbjct: 4802 LR 4803 Score = 79.4 bits (187), Expect = 1e-12 Identities = 129/648 (19%), Positives = 257/648 (39%), Gaps = 57/648 (8%) Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 + +++G+ Q L+ +++ E S E+ T + E+ F + + I + Sbjct: 6390 EASVEGQPQLLEAAIAEIEKVDEISQEISQKTITLLKKTEDTRPQF-ITTEQLIELDVE- 6447 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCVL 1270 D +E+ + + K++ V++D++ + + ++ + I K +++ E ++ Sbjct: 6448 DVRRDLEMKVTSNIIKKEKRRVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLI 6507 Query: 1271 LDAKSTTKLKV-----EVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319 + + TT +V ++V+ PP+I + R + L + P P Sbjct: 6508 QNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECKVEGVPFPEI 6567 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +W N ++ + + ++ + A L I KV +D G+Y +N G A N+ IL+ Sbjct: 6568 KWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNI-ILE 6626 Query: 1380 KPS--PPGKPNILEIDSSSINICWDEPEN---------TG--NSTIIYY--VVEYQEIDT 1424 K PP L+I+ I +PE TG N + +Y + E +T Sbjct: 6627 KEQGVPPQFTKPLKIEF----IEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSET 6682 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSP 1482 + + + N N + + A N+ I +A+ + +V +E +++P Sbjct: 6683 VQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI-LKAP 6741 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXX 1538 TV PL + + + G+P+P+V W R+G+++ +T T E Sbjct: 6742 TVT-PLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVV 6800 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKVGDE-WLV 1592 Y+ A N GE ++S VV QKP I + ++ K+ E ++ Sbjct: 6801 NMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAII 6860 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 A++E P W+ + +++ E I ++ S + I+ + +T A N G Sbjct: 6861 EAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGG 6920 Query: 1653 --TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 TS+ V L ++ + E P + E+ ++ +D L LT K P Sbjct: 6921 SVTSTATVNLIPQEEAEEFESPRFVEEL------VQPVEVMDGEALLLTCQVTGKPTPKV 6974 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 + + + ET Q L C+ + G E + + I Sbjct: 6975 EWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKI 7022 Score = 77.4 bits (182), Expect = 4e-12 Identities = 90/403 (22%), Positives = 160/403 (39%), Gaps = 46/403 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRK-- 1073 P F +K+Q V E + A EVE E V W R+ P +N D + K Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESF---PIQNSPDLQIHTFSGKSI 4450 Query: 1074 LYIRNTSVHDEGEYSCILRDES----CTAEVTVVEL---------PPEIITRLQNQKVNK 1120 L IR V D +SC+ + C+A + V E PP +T +Q+ V Sbjct: 4451 LIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVAT 4510 Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178 G A F+ ++T L V W K+G +IQ S ++ + L I + +D+G Y C Sbjct: 4511 GQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 4570 Query: 1179 ---EVGNSKCTAILTV------EEPSINFTLRLPEFI------LVPANTDAYLTVEIPDE 1223 G ++C V E+P+ + + P + V + + + Sbjct: 4571 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 4630 Query: 1224 -TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTK 1278 T W + ++ ++ + F + + L+I + +D+ Y CV L +++ + Sbjct: 4631 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 4690 Query: 1279 LKVEVVE---FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHT 1334 LKV +E PP I ++ + G + +W ++I + Sbjct: 4691 LKVRPIENLDAPPTITAL-KDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQLIPETPDF 4749 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + D SA L I D+GI+ +R+ ++ G + +T+ Sbjct: 4750 QMIFDGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVESSAKLTV 4792 Score = 76.2 bits (179), Expect = 9e-12 Identities = 75/323 (23%), Positives = 131/323 (40%), Gaps = 35/323 (10%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P ++Q +V + +A FE+E + + V+W+++ IQ S +Q+ K L I Sbjct: 4394 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 4453 Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEP--SINFTLRLPEFILVPANT------- 1212 ++D+ +SC G +KC+A L VEE + ++ P F+ +T Sbjct: 4454 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 4513 Query: 1213 ---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 DA +T P LDV W K I+ + KF ++ + TL+I + +D Y CV Sbjct: 4514 ARFDAKVTGTRP---LDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 4570 Query: 1270 LLDAKSTTKLKVE-VVEFP--------------PKIVDYEREYRIKRGSDVTLLVDYQAF 1314 ++A + + +V+ P P IV+ + ++ GS V Sbjct: 4571 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 4630 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W+ +K ++ + S + L I + D G YK EN G Sbjct: 4631 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 4690 Query: 1375 VTILDKPSPPGKPNILEIDSSSI 1397 + + + P I + S+ Sbjct: 4691 LKVRPIENLDAPPTITALKDVSV 4713 Score = 76.2 bits (179), Expect = 9e-12 Identities = 76/249 (30%), Positives = 125/249 (50%), Gaps = 21/249 (8%) Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEES-EQPIAKTSEIDNEVPEKINVPDDKETS 218 ++ ED +KP S+ + + ++ +LI++ EQ I KT + E EKI K+ Sbjct: 14724 ETVEDVTKPK-SKKKKVVKKKTDDHDELIKKMLEQEIEKT---ELEKYEKIEFDVPKKLK 14779 Query: 219 QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278 + + L PIKIERKE + + + D P+ E + V+LP Sbjct: 14780 P------EFAALEPIKIERKEQKPTKVTILDATDVPKTVKLKPSKRKEKPAEELT-VQLP 14832 Query: 279 KFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVE- 337 KF+LK+R+ + +PP + P + +G+IK NG LSRNI+EA ++ K F P K ++ Sbjct: 14833 KFRLKARM-VLVEYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILK--FKPHKTKKIKK 14889 Query: 338 -KTELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQ-KID 393 K +LE+ L YE + S+++ E K+ E+ PK E+ E + K + K + Sbjct: 14890 IKDDLEKVELEKYEKYISSEEEPEEKTPYKKP-EKAPKPEEKQEDVKLKLGKGKKKPKEE 14948 Query: 394 EIVDEVTIK 402 E + VT+K Sbjct: 14949 EAPENVTLK 14957 Score = 71.3 bits (167), Expect = 3e-10 Identities = 88/343 (25%), Positives = 148/343 (43%), Gaps = 30/343 (8%) Query: 83 EPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXX-----XX 137 E V+LPKF+LK+R+ + ++PP + P T +G+IK NGELSRN++EA Sbjct: 14825 EELTVQLPKFRLKARMVLV-EYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILKFKPHK 14883 Query: 138 XXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAK 197 DLE+V LEK + + S E+E P+ P + + K E K E+ + + K Sbjct: 14884 TKKIKKIKDDLEKVELEKYEKYISSEEE--PEEKTPYKKPEKAPKPEEKQ-EDVKLKLGK 14940 Query: 198 TSE--IDNEVPEKINVPDDKETSQTPTSFNKRSKL--TPIKIERKEMEVSTPQHAETVDG 253 + + E PE + + K Q P + +L P ++E E + P+ E V Sbjct: 14941 GKKKPKEEEAPENVTL---KNIPQKPQEVEEEVELKQKPKEVEIVEEQTKKPKDGEFVVE 14997 Query: 254 PQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGIL 313 P E ++ P+ K + T + P+ S +I + Sbjct: 14998 P--FEPSEFDRPEYVPDELEQIEHPEIPEKVKKPSKTKYKPKDKSK--SEPETIVSEIVA 15053 Query: 314 SRNIKEAAKVKKQV-FVPPKLPDVEKTELEQPLFSYEDIVESKKDEN---EIIQEKQTLE 369 +E A ++ V F P+ E+T+ E L + ++ KDEN + + + E Sbjct: 15054 GVPKEEEAIPEQDVKFRKPERDAPEETDSEIKL---RPVPQASKDENPDEQALVTPKAEE 15110 Query: 370 ELPK--EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEI 410 +P+ ED P+KS +K+ E+ K+ FE+ Sbjct: 15111 PIPQEIEDKAIDDEKKPKKSKPKKVQPKEQEIA-KEEPEEFEV 15152 Score = 69.7 bits (163), Expect = 8e-10 Identities = 89/363 (24%), Positives = 145/363 (39%), Gaps = 57/363 (15%) Query: 520 HTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 +T +G FEC++E P ++ WF+ I F+ +D VA L I + ED Sbjct: 1435 NTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHDFGYVA-LDIVHLIAED 1493 Query: 578 AGTFTCVAKNAAGFASSTTEL-------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630 +G +TC A N G + EL IV ++ G E + +I E Sbjct: 1494 SGVYTCRAVNLIGSDETQVELQCRSGEQIVTVTQNEAGLEQ-IHYLEDRSRYTRREEIDE 1552 Query: 631 GIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIES 686 P F+ K + E ECRL+ + +P + W +P ++ S E+ Sbjct: 1553 STKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNN---LPLKSGSRFTET 1609 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG----------------------EASLPIV 724 + + + L I + GTYT A N G E +LP + Sbjct: 1610 NNFGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRL 1668 Query: 725 LKIKTGEK------------EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCK 770 ++ G K + P P++ + V + ++V A++ VG+P+ T+ W + Sbjct: 1669 QHLEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLR 1728 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 N +P++A + L K V +D G YT +A N G A TSA + V+ T Sbjct: 1729 NGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSI 1788 Query: 829 NAE 831 E Sbjct: 1789 QLE 1791 Score = 69.7 bits (163), Expect = 8e-10 Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 22/262 (8%) Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQ 540 L+K N + + E+ T E + AP+F L ++ +G FE ++ P+ + Sbjct: 3375 LEKIANLEYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLK 3434 Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + W+ +K F+ + D V L I V+PED+G ++C A N G A +T + + Sbjct: 3435 VEWYWNGRPLKAGSRFRTFCDFGFVI-LEISPVYPEDSGEYSCRAINEYGEAVTTATMKI 3493 Query: 601 EAPLS-------DHGSEMTVXXXXXXXXXXXXA-----DILEGIPPTFSKKPKAQYVDEG 648 + S G E T+ + D G PP F P + E Sbjct: 3494 QGKRSIIMESQLPKGMEGTIDRIAELEGLGSRSTEFVPDDDTGKPPEFITSPFDMVIGEN 3553 Query: 649 SDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 + ECRL I +P + W G+ + I +D +L+I + G Sbjct: 3554 ALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTI--NDFGFV--ILEIAGCYQRDSG 3609 Query: 707 TYTVVAVNREGEASLPIVLKIK 728 YT A N+ GEA++ L++K Sbjct: 3610 LYTCKATNKHGEATVSCKLQVK 3631 Score = 69.7 bits (163), Expect = 8e-10 Identities = 102/523 (19%), Positives = 208/523 (39%), Gaps = 34/523 (6%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKV 1281 ++ WY ++ +EK+ + + L I K T D YTC + A S T + + Sbjct: 6566 EIKWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIIL 6625 Query: 1282 EVVE-FPPKI-----VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 E + PP+ +++ E + +R VT+ P P +W + + + + Sbjct: 6626 EKEQGVPPQFTKPLKIEFIEEKQPER-LKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQ 6684 Query: 1336 PSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNVT--ILDKPSPPGK-PNIL 1390 D K+ + ++ + T +A +Y ++ +N G A N+ + + P K P + Sbjct: 6685 MFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREILKAPTVT 6744 Query: 1391 EIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 + + + + E + G + + + I+ E I T T + N+ Sbjct: 6745 PLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTR 6804 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 + ++ +A N+V + +S + + +I+ P +PL+ +E + I Sbjct: 6805 KRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIV 6864 Query: 1506 GGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 P W+ + +K++ + N+ + C A N G V + Sbjct: 6865 ESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTS 6924 Query: 1562 SCVVG-IQQKPVITISN----EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + V I Q+ + E++ Q +V G+ L+T + G P P+V WY N K+ Sbjct: 6925 TATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKIT 6984 Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 +KE I+ + ++I E+ + +Y A+N G S + +K+ P+ + Sbjct: 6985 ENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKIGKSVSKTNVKIQAFEYIPDSEI 7044 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 S E + ++ +D+ ++ K EK EP K+ Sbjct: 7045 TGLTGSEEDL-LDRTLSIDEQAPKIIKKLPEKIEPKEGEQAKL 7086 Score = 66.5 bits (155), Expect = 8e-09 Identities = 61/269 (22%), Positives = 106/269 (39%), Gaps = 20/269 (7%) Query: 498 FEKPTSEEQSM--APIFVEKL-RPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKP 552 +++ EE ++ AP+FV KL P + +G + +EC++E YP P ++ WF + Sbjct: 1810 YQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKPLST 1869 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--------SSTTELIVEAPL 604 F+ YD A L I V+ ED+G +TC N G A +S + +I E Sbjct: 1870 GHRFRTTYDF-GFAALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNVTSRSSIIHETQH 1928 Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP- 663 + +++ + P F + + V+EG+ + LE L+ + +P Sbjct: 1929 EEALTKIQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPT 1988 Query: 664 -DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722 + W G I + L I GTY A N GEA Sbjct: 1989 MKVEWYCNGRPIQTGHRFKTTYDFGF----VALDILYAHAEDTGTYMCKAKNAIGEAVTT 2044 Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + + + ++ + +RQ E+ Sbjct: 2045 CAVNVTANKTLDLDTLDAQRLEKIRQLET 2073 Score = 65.7 bits (153), Expect = 1e-08 Identities = 67/257 (26%), Positives = 105/257 (40%), Gaps = 24/257 (9%) Query: 481 TQYLQKKLNEKIDKLP--VFEKPTSEEQSMA---PIFVEKLR-PKHTPDGSTVQFECQVE 534 T + + L EK L F +P + + ++ P+FV L PK DG + EC++E Sbjct: 1124 TSSMHRGLYEKTQNLENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLE 1183 Query: 535 --GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 G P ++ WF + F+ YYD VA +I+ D+G +T A N G A Sbjct: 1184 PMGDPTMRVEWFHNGRPVTVGSRFRTYYDFGFVALDIIKAT-AADSGEYTVRATNHLGTA 1242 Query: 593 SST--------TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 ++ T+++ E ++ E DI P F++ Sbjct: 1243 HTSACVRVIDHTDVVTETQ-NEQSLEQIQLLEDSRRRHHQEEDITIMQAPQFTRGLHNIE 1301 Query: 645 VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 EG+++ LECRL + +P I W G+ + A E D Y + L + Sbjct: 1302 TIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFD---YVA-LDLLGCYA 1357 Query: 703 FQEGTYTVVAVNREGEA 719 G YT A N+ GEA Sbjct: 1358 IDSGVYTCQARNQLGEA 1374 Score = 65.3 bits (152), Expect = 2e-08 Identities = 93/376 (24%), Positives = 150/376 (39%), Gaps = 56/376 (14%) Query: 496 PVFEKPTSEEQSMA-PIFVEKLR-PKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIK 551 P+ +PT E+ PIF + L P +G+ FE +V G P + WF ++ Sbjct: 2473 PLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSLKFEWFINGVELQ 2532 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 + +D V TL I V PEDAG + C A NAAG A S+T + V+ + G + Sbjct: 2533 MGSRLRTTHDFGFV-TLDITAVVPEDAGVYMCRAYNAAGEAVSSTAMKVKTKSNIDGQPL 2591 Query: 612 TVXXXXXXXXXXXXAD-----ILEGIP---PTFSKKPKA-QYVDEGSDILLECRLVAIPE 662 + ++ P P F+ ++ + EG +LLE ++ + Sbjct: 2592 IPESWEAIRLKEAAMNRVPEMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRAD 2651 Query: 663 PD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA- 719 P+ I W G + I S L I ++ YT A N+ GEA Sbjct: 2652 PNLRIEWFKNGISLTTGSR----IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAV 2707 Query: 720 ---------------------SLPIVLKIKTGEKEPPQVIEP----------LKSMIVRQ 748 SLP + +++ ++ P+ EP L ++ ++ Sbjct: 2708 STSSLKIEDRHWLQAESLHPDSLPRIGELEAPKEGRPEAPEPTYETPVFITHLNNIECKE 2767 Query: 749 GESVILSAQV--VGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYT 804 ++V V +P +I W N +P++A KS D + L ++ GVYT Sbjct: 2768 SDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCALDLTNSYAENSGVYT 2827 Query: 805 LKAENSEGIAETSAVI 820 KA NS+G A TS + Sbjct: 2828 CKATNSKGSATTSGTL 2843 Score = 63.3 bits (147), Expect = 7e-08 Identities = 60/238 (25%), Positives = 97/238 (40%), Gaps = 20/238 (8%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 AP F L T +G+ V EC+++ G P +I WF +K F+ Y+ D VA Sbjct: 1290 APQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYVA 1349 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASST--------TELIVEAPLSDHGSEMTVXXXXX 618 L + + D+G +TC A+N G A ++ +LI+E ++ Sbjct: 1350 -LDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQKIQYLEDST 1408 Query: 619 XXXXXXXADILEGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIV 675 D + I P F PK+ EG EC++ + +P+ + W G I Sbjct: 1409 RHRRSEFVDEVVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPIT 1468 Query: 676 PDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 +H + V L I ++ G YT AVN G + L+ ++GE+ Sbjct: 1469 VGHRFR-----PIHDFGYVALDIVHLIAEDSGVYTCRAVNLIGSDETQVELQCRSGEQ 1521 Score = 63.3 bits (147), Expect = 7e-08 Identities = 61/241 (25%), Positives = 95/241 (39%), Gaps = 21/241 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYD 561 E AP+F L+ + FEC++ P ++ W+ +K F + Sbjct: 1552 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 1611 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL-----SDHGSEMTVXXX 616 VA L I PEDAGT+TC A NA G A ++ +V S H + + Sbjct: 1612 FGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRLQH 1670 Query: 617 XXXXXXXXXADILEGI---PPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAWLFKG 671 + + P F+ + V E + E RL+ + +P + WL G Sbjct: 1671 LEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNG 1730 Query: 672 EEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIK 728 + I + MH + V L + V GTYT AVN G+A S ++++ K Sbjct: 1731 QPIEASNRTTT-----MHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSK 1785 Query: 729 T 729 T Sbjct: 1786 T 1786 Score = 62.9 bits (146), Expect = 9e-08 Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 18/234 (7%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 S AP+F +R + V FE ++ G P+ + W R I+ S +D Sbjct: 1688 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 1747 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGSEMTVXXXXXX 619 VA L ++ V PED+GT+TC A N G A ++ LIV++ S H + M Sbjct: 1748 VA-LNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSIQLETQHEAAMHKIHQLED 1806 Query: 620 XXXXXXADILE---GIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673 + E P F +K + EG ECR+ P+P+ + W G+ Sbjct: 1807 HSRYQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKP 1866 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 + + + L I V G YT N GEA IVL + Sbjct: 1867 LSTGHRFRTTYDFGF----AALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNV 1916 Score = 62.1 bits (144), Expect = 2e-07 Identities = 107/485 (22%), Positives = 186/485 (38%), Gaps = 59/485 (12%) Query: 947 ILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 +LEC+ KWY N + + EI + DVGV C K++ Sbjct: 6554 VLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNE 6613 Query: 1005 ------ETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETA-----DVVWERD 1052 T+ +L ++ +P +F + L+ ++EK L+V + + +V W R Sbjct: 6614 AGVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRG 6673 Query: 1053 GEIIKPKKNKYDF--EKRGHIRKLYIRNT-------SVHDEGEYSCILRDESCTAEVTVV 1103 E + P + F EK G + I T SV + ++ + + + + V Sbjct: 6674 IEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVD-- 6731 Query: 1104 ELPPEI-----ITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQL 1154 E+P EI +T L V G FE K D L V+W ++G EI + + Sbjct: 6732 EVPREILKAPTVTPLSAVVVPTGGTLFFE---AKYDGLPRPEVKWMRNGREIIENEETII 6788 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LV 1208 +K+ + G+Y +VG +K + + V + + ++ P FI L Sbjct: 6789 ETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLE 6848 Query: 1209 PA----NTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 P + A + + E L W+ I+ + + ++S K TL+I Sbjct: 6849 PKYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFV 6908 Query: 1264 CEYTCVL------LDAKSTTKL----KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 +TC + + +T L + E E P + + + + G + L Sbjct: 6909 GPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTG 6968 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 P P EW N++ I + K T S D + L I +V + G Y+ N G + + Sbjct: 6969 KPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVATNKIGKSVSK 7028 Query: 1373 MNVTI 1377 NV I Sbjct: 7029 TNVKI 7033 Score = 60.5 bits (140), Expect = 5e-07 Identities = 55/238 (23%), Positives = 92/238 (38%), Gaps = 21/238 (8%) Query: 505 EQSMAPIFVEKLRPKHT-PDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561 ++ P FV +++ + T + + +FECQ+ G P ++ WF + FQ YD Sbjct: 3949 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 4008 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAG--------FASSTTELIVEAPLSDHGSEM-- 611 VA + V+PED+G + C A N G S ++ ++ L H + Sbjct: 4009 FGYVA-MNFGWVYPEDSGEYVCRATNLYGKDETRAIIKVSGKPGIVYDSQLPAHMQSIDR 4067 Query: 612 --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669 + D P F K + Q V+EG R+ P P + WL Sbjct: 4068 IREMEASWQVVPDEVDPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLI 4127 Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 G +V + + H L + +++ G V+A N GE+ LK+ Sbjct: 4128 NGHTVVHGSRYKLTNDGMFH-----LDVPKTRQYDTGKVEVIARNSVGESIATTELKV 4180 Score = 58.0 bits (134), Expect = 3e-06 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568 P+F + + G FE ++ G P+P +TW R+ A + SQ F+M Y++ +L Sbjct: 87 PVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSL 146 Query: 569 VIREVFPEDAGTFTCVAKNAAGFA 592 +I ++ P D G +TC A+N G A Sbjct: 147 LINQIGPGDEGEYTCTARNQYGEA 170 Score = 57.2 bits (132), Expect = 5e-06 Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 32/334 (9%) Query: 504 EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQ--ITWFRQTAIIKPSQDFQMYY 560 E Q P++ + L+ + H + + E VE P I W+ ++ F+M Sbjct: 2886 ETQYPPPVWTKPLQAEFHLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMT- 2944 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTT------ELIVEAPLSDHGSEMTV 613 + T+ + EV+ D G +TC A N AG A +STT E I+E+ G+E Sbjct: 2945 SEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTTIFCSSKENIIESTQHPKGAEGLE 3004 Query: 614 XXXXXXXXXXXXADILE----GIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD--IA 666 E GIPP F+ + + EG E L+ + + I Sbjct: 3005 QIQDLEDSLRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIE 3064 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W + G+ + + ++ + +V L++ K GTYT A N+ G A + L Sbjct: 3065 WFYNGKVLEASHRVRT-----IYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNL 3119 Query: 726 K-IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---AL 778 + + + P+ I+PL+ + Q + V +P + W N K ++ + Sbjct: 3120 ECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRI 3179 Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 T SD + + + + D G Y +A N G Sbjct: 3180 KTVSDFG-YVVLDISYLQDHDSGEYVCRAWNKYG 3212 Score = 56.4 bits (130), Expect = 8e-06 Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 24/253 (9%) Query: 481 TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVE--GYP 537 T+ LQK L E + K E T +EQ P F E+++ P+G + F+C+VE G P Sbjct: 3650 TESLQK-LEETMHKRE--ELVTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDP 3706 Query: 538 RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 +I WF ++ D +A L + ++ D+G +TC A N G A+++ + Sbjct: 3707 TMRIEWFYNGHVMATGSRVHQLNDFGFIA-LDVDYIYARDSGEYTCRATNKWGTATTSAK 3765 Query: 598 --------LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYVDE 647 ++ E+ L + G ++E + PP F+ + + VDE Sbjct: 3766 VTCKGKHNIVYESQLPE-GMTSEKLKELERGRIPEAPKVVEEVFGPPKFTTQITSVTVDE 3824 Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + EC++ +P + W G+ + P + + M L I V Sbjct: 3825 AEAVRFECQVEPKTDPSLRVEWYRNGKPL-PSGH---RYRNIFDMGFVSLDILYVYGEDS 3880 Query: 706 GTYTVVAVNREGE 718 G Y A+N GE Sbjct: 3881 GEYVCRAINNYGE 3893 Score = 55.6 bits (128), Expect = 1e-05 Identities = 83/378 (21%), Positives = 146/378 (38%), Gaps = 40/378 (10%) Query: 370 ELPKEDVPEQYTI-TPRKSSAQKIDE---IVDEVTIKKRLNP---FEIFYTPVEVRCGDT 422 E+ + P+Q + T S K+ E ++ E ++ R +P E F + + G Sbjct: 2611 EMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSR 2670 Query: 423 VFAVYSYVAETDEAINL-VEGERLYILDTSNQDWWYVQKHLT--EEKGWVPAQYLMDENN 479 + + + + T L + +Y +NQ V E++ W+ A+ L ++ Sbjct: 2671 IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDRHWLQAESLHPDSL 2730 Query: 480 YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY--P 537 +L + P +PT E P+F+ L + V+FEC VE P Sbjct: 2731 PRI---GELEAPKEGRPEAPEPTYE----TPVFITHLNNIECKESDNVRFECNVEPARDP 2783 Query: 538 RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--- 594 I WF ++ + F+ YD A L + + E++G +TC A N+ G A++ Sbjct: 2784 TMSIEWFYNGQPLQAAAKFKSIYDFGYCA-LDLTNSYAENSGVYTCKATNSKGSATTSGT 2842 Query: 595 -------TTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 T L + P + G E T + PP ++K +A++ Sbjct: 2843 LKCTGGKTMFLDTQHPQGEAGLEAVQETEEELANRYTSKTTKPETQYPPPVWTKPLQAEF 2902 Query: 645 -VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 + E I LE + +P+ I W F G+ + + E + + V Sbjct: 2903 HLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMTSEFGF----VTMDMIEVY 2958 Query: 702 KFQEGTYTVVAVNREGEA 719 +G YT A N+ GEA Sbjct: 2959 ARDQGIYTCKAYNKAGEA 2976 Score = 55.6 bits (128), Expect = 1e-05 Identities = 58/274 (21%), Positives = 106/274 (38%), Gaps = 23/274 (8%) Query: 1464 ASETTE--YYKVIKETKIQSPT--VEKPLKNITTEP-----NEDIELTCIFGGVPQPKVT 1514 A+ETTE + I+E +Q P + P+ +P NE + F G P P V Sbjct: 4367 ATETTEVEHKGTIQERVVQGPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVK 4426 Query: 1515 WYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 WYR+ ++ + T+ + + C+A N G + S + ++++ Sbjct: 4427 WYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEER 4486 Query: 1571 P------VITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 + S Q V L A + G P +V W KNG K++ ++ + Sbjct: 4487 RRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKML 4546 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 ++ + I E S +Y A N AG + + + PSKPE P Sbjct: 4547 EEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDGDC-IVQSPSKPEKPTTPGSEKAPH 4605 Query: 1683 VTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIK 1715 + + K +++G + + ++ RW++ Sbjct: 4606 IVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMR 4639 Score = 55.2 bits (127), Expect = 2e-05 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 4/127 (3%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 DE Y + KL + +P E AP + L+ +G QF+ V G Sbjct: 4670 DEGTYKCVAENKLGSIQTSAQLKVRPI--ENLDAPPTITALKDVSVTEGMPAQFKTTVTG 4727 Query: 536 YPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 + + WFR+ +I + DFQM + D N A L+I + ED+G FT ++ G S Sbjct: 4728 KVKATSVQWFREGQLIPETPDFQMIF-DGNSAVLLIGTTYEEDSGIFTVRVTSSTGQVES 4786 Query: 595 TTELIVE 601 + +L V+ Sbjct: 4787 SAKLTVK 4793 Score = 54.4 bits (125), Expect = 3e-05 Identities = 63/246 (25%), Positives = 103/246 (41%), Gaps = 21/246 (8%) Query: 490 EKIDKLPVFE---KPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQITW 543 EKI +L + KP EE+ PIF+ L +H +G EC+VE P +I W Sbjct: 2066 EKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPINDPNLKIEW 2125 Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--- 600 F + ++ +D VA L I V+ ED GT+ C A N G A +T + V Sbjct: 2126 FCNGKQLPTGHRYRTTHDFGYVA-LDILYVYGEDTGTYICKATNQLGEAVNTCNVRVLNR 2184 Query: 601 EAPLSD--HGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK-AQYVDEGSDILLEC 655 + + D H + ++ + PP F+ + + + + EG E Sbjct: 2185 RSMILDTQHPDALEKIQKLESKVPNARTEVGDAPISPPHFTAELRGSTEIYEGQTAHFEA 2244 Query: 656 RLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 ++ + +P+ I + G+ + + + Y S L IT+ G Y+V AV Sbjct: 2245 QVAPVHDPNLRIEFYHNGKPLPSASRFHITFDFG---YVS-LDITHAVAEDAGEYSVRAV 2300 Query: 714 NREGEA 719 N G+A Sbjct: 2301 NALGQA 2306 Score = 53.6 bits (123), Expect = 6e-05 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+FV KL P+ +G +F +V G+PRP++ W + +++ +D + L Sbjct: 4092 PVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKL--TNDGMFHLD 4149 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + + D G +A+N+ G + +TTEL V A D+ Sbjct: 4150 VPKTRQYDTGKVEVIARNSVGESIATTELKVVARSDDY 4187 Score = 51.2 bits (117), Expect = 3e-04 Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 15/193 (7%) Query: 1091 LRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK-GDA--LVRWFKDGSEI 1146 LR + E + +PP T N + +G A FE L GD ++ WF +G + Sbjct: 3013 LRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIEWFYNGKVL 3072 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT-----VEEP---SINF 1198 + S+ ++ L++ ++D G Y+C N TA ++ V++P F Sbjct: 3073 EASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVDKPRGQKPRF 3132 Query: 1199 TLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 T + + A+ + + D L V WY ++ + + +SD L I Sbjct: 3133 TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDI 3192 Query: 1256 RKCTEDDQCEYTC 1268 + D EY C Sbjct: 3193 SYLQDHDSGEYVC 3205 Score = 50.8 bits (116), Expect = 4e-04 Identities = 59/237 (24%), Positives = 90/237 (37%), Gaps = 23/237 (9%) Query: 507 SMAPIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQ----ITWFRQTAIIKPSQDFQMYYD 561 + AP F+ L+ +G FE +VE P+ I W+ I + Q YYD Sbjct: 1021 TQAPRFLGPLKGTTKILEGQRAHFEARVE--PQSDLGLVIEWYHNGRSITAANRIQTYYD 1078 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM---------T 612 VA L I +V EDAG + VA+N G A +IVE S S M Sbjct: 1079 FGYVA-LDISQVRAEDAGVYLVVARNKLGEAQQQATMIVETRSSIDTSSMHRGLYEKTQN 1137 Query: 613 VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFK 670 + +I + P + + + +G +I LECRL + +P + W Sbjct: 1138 LENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHN 1197 Query: 671 GEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 G + + + ++K T G YTV A N G A +++ Sbjct: 1198 GRPVTVGSRFRTYYDFGF-VALDIIKATAA---DSGEYTVRATNHLGTAHTSACVRV 1250 Score = 50.0 bits (114), Expect = 7e-04 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 8/175 (4%) Query: 746 VRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDE 800 + +GE A + VG+ I W N K ++A + T T ++ +L K ++D Sbjct: 3041 IGEGELAHFEANLIPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTK-IEDT 3099 Query: 801 GVYTLKAENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G YT +A N G AE S + V++P + I + + + + + Sbjct: 3100 GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVND 3159 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P + WY N +++ S I D + L I+ + DSG+Y C A N G+ Sbjct: 3160 PDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDH-DSGEYVCRAWNKYGE 3213 Score = 50.0 bits (114), Expect = 7e-04 Identities = 76/393 (19%), Positives = 145/393 (36%), Gaps = 32/393 (8%) Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 R+ V+++ P P +W S I+ + S + L I++V D+ + Sbjct: 4404 RVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAV 4463 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNI------LEIDSSSI---NICWDEPENTG 1408 + EN G A N+ ++++ GK I I S+++ + + + TG Sbjct: 4464 FSCVAENRGGTAKCSANL-VVEERRRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTG 4522 Query: 1409 NSTI-IYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDISDASE 1466 + +Y++ +I + + T I S R+ AVN + Sbjct: 4523 TRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDG 4582 Query: 1467 TTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 K K +P EK LK+ T E + C G P P W R Sbjct: 4583 DCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGEN 4642 Query: 1521 KLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSC------VVGIQQK 1570 +K ++ +R YKC+A N G ++TS + + Sbjct: 4643 FVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVRPIENLDAP 4702 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P IT + +D+ + ++ T V + V W++ G + ++ + ++V+ Sbjct: 4703 PTIT-ALKDVSVTEGMPAQF-KTTVTGKVKATSVQWFREGQLIPETPDFQMIFDGNSAVL 4760 Query: 1631 RIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661 I S +T+ +++ G SS ++T+K Sbjct: 4761 LIGTTYEEDSGIFTVRVTSSTGQVESSAKLTVK 4793 Score = 48.8 bits (111), Expect = 0.002 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQ 881 E E E P+FI I KE ++ V R+P SI W+ N + + + Sbjct: 2745 EAPEPTYETPVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKS 2804 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 +D L +TN +E +SG Y C A+NS G ++ + K F+ Sbjct: 2805 IYDFGYCALDLTNSYAE-NSGVYTCKATNSKGSATTSGTLKCTGGKTMFL 2853 Score = 48.0 bits (109), Expect = 0.003 Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 10/176 (5%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D E+ E + + + +V W +G ++ + L Sbjct: 372 PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 431 Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127 I N + D G C+ R+++ A++ V+E + P+ + R V +G T Sbjct: 432 ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 491 Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + + W KDG +I + + IDG L+I +DAG Y C N Sbjct: 492 ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQN 547 Score = 48.0 bits (109), Expect = 0.003 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 11/228 (4%) Query: 201 IDNEVPEKINVPDDKETSQTP------TSFNKRSKLTPIKIERKEM-EVSTPQHAETVDG 253 I E+P+ + P + + P +SF + KLTP+KIE+ E + + + V+ Sbjct: 11813 IHQEIPKTVLQPYQRTEMELPQRARRDSSFKQPVKLTPMKIEKVEFKKPKMVEISSVVEF 11872 Query: 254 PQFXXXXX-XXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGI 312 PQ + + +LKS I+++ + P +++ + + ++ G Sbjct: 11873 PQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIRFV-PYAPYCFPYVVTELETNREVGE 11931 Query: 313 LSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372 LSRN+ EA +V K K EK ELE+ + S K E++ K + Sbjct: 11932 LSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLGAYESDHSDKSNKELLHPKYKRGKKE 11991 Query: 373 KEDVP-EQYTITPRKSSAQKIDEIVDEVTIKK-RLNPFEIFYTPVEVR 418 K + P E + K + +E +EV +K +L+ EI + VR Sbjct: 11992 KIETPDESRKLKFGKGKVPQNEEASEEVNLKPVKLDIAEIEDAEMPVR 12039 Score = 47.2 bits (107), Expect = 0.005 Identities = 62/270 (22%), Positives = 100/270 (37%), Gaps = 23/270 (8%) Query: 499 EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555 ++P + P+F + L+ + T FE ++ G P ++ W+R II+ S Sbjct: 2345 QEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSR 2404 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615 +D V+ L I + ED G + C A N G A +T + V +S+ +M Sbjct: 2405 ITKQHDFGFVS-LDISHIRKEDEGVYMCRAVNPLGEAVTTASMRV---VSEASIQMDTQH 2460 Query: 616 XXXXXXXXXXADILEGIPP----TFSKKPKAQYVD------EGSDILLECRLVAIPEPDI 665 L P F K Q + EG+ E R+V + +P + Sbjct: 2461 PDSISRIHQLEKPLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSL 2520 Query: 666 --AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723 W G E+ + + + L IT V G Y A N GEA Sbjct: 2521 KFEWFINGVEL----QMGSRLRTTHDFGFVTLDITAVVPEDAGVYMCRAYNAAGEAVSST 2576 Query: 724 VLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 +K+KT Q + P +R E+ + Sbjct: 2577 AMKVKTKSNIDGQPLIPESWEAIRLKEAAM 2606 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 5/104 (4%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNNEIISPSETITQNFD 884 EE PP F + +TV E ++ +V PS + WYRN + + FD Sbjct: 3805 EEVFGPPKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFD 3864 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + L I V E DSG+Y C A N+ G+ R T+ +K+ Sbjct: 3865 MGFVSLDILYVYGE-DSGEYVCRAINNYGEDR--TRATVSCKKL 3905 Score = 46.8 bits (106), Expect = 0.007 Identities = 31/117 (26%), Positives = 61/117 (52%), Gaps = 9/117 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 PPQ I PL+++ +G V + A++ VG+P + W N +P+ A + Sbjct: 617 PPQFIIPLQNVQQTEGGRVHMEARIEPVGDPTMVVEWYLNGRPLAASARATSVFKFGFIA 676 Query: 792 LKPKKVK--DEGVYTLKAENSEGIAETSAVIT-VEEPT-EENAEPP---LFINRFQE 841 L + D G Y + N+ G+AE+ A+++ V+ P+ E++++ P +IN+ ++ Sbjct: 677 LDLLSIMGHDSGEYMCRVTNASGVAESRAILSVVQRPSIEQSSQNPNSLQYINQLED 733 Score = 46.8 bits (106), Expect = 0.007 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 5/105 (4%) Query: 815 ETSAVITVEEP-TEENAEPPLFINRFQEIT-VKEKGTIKLVARV--TRNPVPSITWYRNN 870 E++A +EP T + P+F Q I + E T AR+ +P + WYRN Sbjct: 2337 ESTAPHQRQEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNE 2396 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 +II S IT+ D + L I+++ E D G Y C A N G++ Sbjct: 2397 KIIEDSSRITKQHDFGFVSLDISHIRKE-DEGVYMCRAVNPLGEA 2440 Score = 45.2 bits (102), Expect = 0.020 Identities = 37/157 (23%), Positives = 67/157 (42%), Gaps = 13/157 (8%) Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 + + ++ + W +G++++ G + L + T + D G Y+C ++ T Sbjct: 3054 IPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVA-LEVLGTKIEDTGTYTCRATNKHGT 3112 Query: 1098 AEVTV----VELP----PEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSE 1145 AE++ V+ P P + +Q + + G A FE I + D V W+ +G Sbjct: 3113 AEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 3172 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 ++ SN I+ D L I D+GEY C N Sbjct: 3173 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWN 3209 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Query: 827 EENAEPPLFINRFQE-ITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNF 883 +E PP F ++ + V E G I RV +P I W+ N +++ + Q Sbjct: 3670 DEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVHQLN 3729 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 D I L + + + DSG+Y C A+N G ++ A+VT Sbjct: 3730 DFGFIALDVDYIYAR-DSGEYTCRATNKWGTATTSAKVT 3767 Score = 44.0 bits (99), Expect = 0.046 Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 17/212 (8%) Query: 44 LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVK----LPKFQLKSRIK 99 L ++IE++E KP+ E +V +F QE K +LKS I+ Sbjct: 11848 LTPMKIEKVEFKKPKMVEISSVVEFPQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIR 11907 Query: 100 FIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLF 159 F+ + P +VT L + ++ GELSRNV EA E+ LE++DL Sbjct: 11908 FV-PYAPYCFPYVVTELETNREVGELSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLG 11966 Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219 + D S D S + PK ++ I E K VP ++E S+ Sbjct: 11967 AYESDHS--DKS-------NKELLHPKYKRGKKEKIETPDESRKLKFGKGKVPQNEEASE 12017 Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETV 251 K KL +IE EM V T Q E V Sbjct: 12018 EVNL--KPVKLDIAEIEDAEMPVRT-QEEEVV 12046 Score = 43.6 bits (98), Expect = 0.061 Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 5/103 (4%) Query: 825 PTEENA--EPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880 P EE+ PP FI Q + E G + + AR+ +P + WY N ++ S T Sbjct: 608 PGEEDRVYPPPQFIIPLQNVQQTEGGRVHMEARIEPVGDPTMVVEWYLNGRPLAASARAT 667 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 F I L + ++ DSG+Y C +N++G + A +++ Sbjct: 668 SVFKFGFIALDLLSIMGH-DSGEYMCRVTNASGVAESRAILSV 709 Score = 42.7 bits (96), Expect = 0.11 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F + K +G + L E RL P+P + W KG ++ + ++ ++ Sbjct: 86 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSY-NEATGDV 144 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S+L I + EG YT A N+ GEA + ++ + Q I+ L+ I G S Sbjct: 145 SLL-INQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPIQNLEKNIYSNGYS 202 Score = 42.7 bits (96), Expect = 0.11 Identities = 21/78 (26%), Positives = 35/78 (44%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 IS + K G + + TA + P P + W+ NG +L ++Y I+ + +R+K Sbjct: 257 ISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRVKN 316 Query: 1635 LKRSHSSKYTIEASNTAG 1652 YT+ A N G Sbjct: 317 ATARDGGHYTLLAENLQG 334 Score = 42.3 bits (95), Expect = 0.14 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 6/120 (5%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880 EE E + P+F + + +KE R+ +P + WY NN + T Sbjct: 1548 EEIDESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFT 1607 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + + + L I + E D+G Y C A N+ G++ A + +K + L+ +ET Sbjct: 1608 ETNNFGFVALDIMSTLPE-DAGTYTCRAYNAVGEAITSAVAVVHTKKSIY---LESQHET 1663 Score = 42.3 bits (95), Expect = 0.14 Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 14/160 (8%) Query: 1461 ISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWY 1516 I +T+ + + E + + P +PL+N + L T I P KV WY Sbjct: 1935 IQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWY 1994 Query: 1517 RDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +G+ ++T K TY+ Y C A N GE T+C V + Sbjct: 1995 CNGRPIQTGHRFKTTYDFGFVALDILYAHAEDTGTYMCKAKNAIGEAVTTCAVNVTANKT 2054 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 + + D ++ K+ L T PPP+ + + G K Sbjct: 2055 LDLDTLDAQRLEKI--RQLETYA----PPPKPVVEEKGQK 2088 Score = 42.3 bits (95), Expect = 0.14 Identities = 59/249 (23%), Positives = 103/249 (41%), Gaps = 22/249 (8%) Query: 164 DESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK-ETSQTPT 222 +ES D P ++ EA E + SE+P K E++ E EK DDK ET++ Sbjct: 13747 EESIIDEPIPEDYVVTEAAEE----KPSEEPTFKVEELETEAVEKEVTDDDKGETTKQSV 13802 Query: 223 SFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQL 282 + K KL K E E+ V T +T D P++ E P+ + Sbjct: 13803 TKRKIKKLVGPKEEIIEI-VET----KTGDTPEYEVIVTTEEVQEKSKEA-----PEEKK 13852 Query: 283 KSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL- 341 ++ P + ++ Y+ + + I +++ K+ V K ++K + Sbjct: 13853 AKTVRKAKKIPKDDLQ---DYIQKLIEQDIPKTELEKYEKIDLDEPVKMKRKPIKKVKQS 13909 Query: 342 -EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVT 400 EQP E+ +E K E +I + + + PK V + I P K + + +V E T Sbjct: 13910 EEQPKEETEEPIEDKPVE-KISEYSEVDSDEPKLTVAVKEFI-PEKPEEKPFEIVVLEET 13967 Query: 401 IKKRLNPFE 409 ++ + P E Sbjct: 13968 VESKREPDE 13976 Score = 41.5 bits (93), Expect = 0.25 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIE 889 PP+F F+ + G R+ NP P +TW R + S+ +++ ++ Sbjct: 86 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVS 145 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKS 915 L+I + D G+Y C A N G++ Sbjct: 146 LLINQIGPG-DEGEYTCTARNQYGEA 170 Score = 41.1 bits (92), Expect = 0.33 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 8/115 (6%) Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFG--GVPQPKVTWYRDGKKLKTA---KATYE- 1530 T +Q+P + L NI T ++ L C G P ++ W+ +GK +KT + YE Sbjct: 1286 TIMQAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEF 1345 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQK 1583 + Y C A N GE TSC V I K ++ NE QK Sbjct: 1346 DYVALDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQK 1400 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 12/129 (9%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGD 785 G+ PP + K+ QG + + ++ GNP+P +TW + P+ K + ++ Sbjct: 82 GDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEAT 141 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------EPTEENAEPPLFINR 838 ++ DEG YT A N G A S I E +P +N E ++ N Sbjct: 142 GDVSLLINQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPI-QNLEKNIYSNG 200 Query: 839 FQEITVKEK 847 + +++E+ Sbjct: 201 YSYTSIEEE 209 Score = 40.7 bits (91), Expect = 0.43 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYNITTKE 1625 QQ PV T + + H+ G L+ A +E P + W+KNG L T Sbjct: 2619 QQAPVFTTHLQSYDKLHE-GQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDF 2677 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + I L+ S+ YT +A+N G + +LK+ D+ Sbjct: 2678 GLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDR 2717 Score = 40.7 bits (91), Expect = 0.43 Identities = 18/90 (20%), Positives = 42/90 (46%) Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 ++ ++ + P +++ R+ R G + + P P+ +W N+ ++ + + Sbjct: 7179 QVALKAAKCSPSLLNEMRDCRAALGETAKFSIQFAGNPIPDIQWYFNNVQLRASEKYRMV 7238 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + + A+L I K+ + D G Y +L N G Sbjct: 7239 VQEQEATLEIMKITSEDCGYYNCKLINEIG 7268 Score = 40.3 bits (90), Expect = 0.57 Identities = 64/298 (21%), Positives = 114/298 (38%), Gaps = 39/298 (13%) Query: 1107 PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P+I + ++ K+ +G+ A F + + + WF +G + S +++ L++ Sbjct: 255 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRV 314 Query: 1166 YDCDLDDAGEYSCEVGNSK-C---TAILTVE-------EPS-INFTLRLPEF--ILVPAN 1211 + D G Y+ N + C +A+L VE EP ++ E L PA Sbjct: 315 KNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPPAF 374 Query: 1212 TDAYLTVEIPDETL-------------DVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRK 1257 A+ EI + + +V W + V +D L+++ +L+I Sbjct: 375 VKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITN 434 Query: 1258 CTEDDQCEYTC--------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 T D C V ++A+ K +VV P+ V ++ G +T+ Sbjct: 435 VTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVA--PQFVQRFSTMTVREGEPITMSA 492 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + PQP W + I ID + L I +V DAG Y+ +N G Sbjct: 493 NAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAG 550 Score = 40.3 bits (90), Expect = 0.57 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 732 KEPPQVIEPLKS-MIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGD 785 K P + PL + G+++ L ++ +G+P + W N +PV T D Sbjct: 1155 KSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSRFRTYYDFG 1214 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 ++ I+K D G YT++A N G A TSA + V + T+ Sbjct: 1215 FVALDIIKATAA-DSGEYTVRATNHLGTAHTSACVRVIDHTD 1255 Score = 40.3 bits (90), Expect = 0.57 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 7/124 (5%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP--KVTWYRD 1518 + D S T ++ + TK Q+P LKN+ + N+ C V P +V WY + Sbjct: 1538 LEDRSRYTRREEIDESTK-QAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHN 1596 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 LK+ E Y C A+N GE TS V + K I Sbjct: 1597 NLPLKSGSRFTETNNFGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIY 1656 Query: 1575 ISNE 1578 + ++ Sbjct: 1657 LESQ 1660 Score = 40.3 bits (90), Expect = 0.57 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDGEN 887 ++ P+F +++ V E + AR+ +P ++ W RN + I S T D Sbjct: 1688 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 1747 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + L + V+ E DSG Y C A N G++ A + + Sbjct: 1748 VALNMKYVNPE-DSGTYTCRAVNELGQAVTSASLIV 1782 Score = 40.3 bits (90), Expect = 0.57 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%) Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 I+ + DF D++ L+ + E W + GE + + RG + ++ Sbjct: 3179 IKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYGEDFT--RTTLNCGGRGGVFYDSLQPD 3236 Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK---GDA 1135 S+ E C ++ T+ V E PP+ IT++ + K+ +G A FE LT D Sbjct: 3237 SLQRIRELECPQGQQADTSAPLVAE-PPKFITQIVDVTKLVEGQSAHFEARLTPITDPDL 3295 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 +V W+ +G ++ + + D L I C +++G Y N Sbjct: 3296 VVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARN 3342 Score = 39.9 bits (89), Expect = 0.75 Identities = 36/196 (18%), Positives = 77/196 (39%), Gaps = 10/196 (5%) Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 C G P P+V W +G++++ + +C+A N G Sbjct: 393 CRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITNVTRLDAGAVQCLARNKAG 452 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 EV + + +K + ++ + +++ + G+ ++A G P P + W K+G ++ Sbjct: 453 EVAIEAQLNVLEKEQV-VAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQI 511 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 + E + + + I + + + Y A N AG+++ L V +P Sbjct: 512 SSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQ 571 Query: 1674 IMREISRESVTIEWKP 1689 + R + IE +P Sbjct: 572 RRLNLPRPTKVIEPEP 587 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 +P + P+F+++ + TV+E + RVT +P P + W N + Sbjct: 4083 DPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKLTN 4142 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 DG L + + D+G + +A NS G+S Sbjct: 4143 DG-MFHLDVPKT-RQYDTGKVEVIARNSVGES 4172 Score = 39.5 bits (88), Expect = 0.99 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 4/102 (3%) Query: 504 EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGY--PRPQITWFRQTAIIKPSQDFQMYY 560 E+ + AP F+ LR +G V FE QV P ++ W++ I S + Sbjct: 745 EQLNQAPQFIRPLRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIF 804 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + V+ L I + EDAGT+T A N G A S + + V + Sbjct: 805 NFGYVS-LNILHLRAEDAGTYTVRAVNRIGEAISQSSIRVHS 845 Score = 39.5 bits (88), Expect = 0.99 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787 E PQ PL++ V +G V L A + V +P + W N +P++ T D Sbjct: 1956 ERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFV 2015 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ IL +D G Y KA+N+ G A T+ + V Sbjct: 2016 ALDILYAH-AEDTGTYMCKAKNAIGEAVTTCAVNV 2049 Score = 39.1 bits (87), Expect = 1.3 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 1106 PPEIITRLQNQ-KVNKGNKATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161 PP+ T +QNQ + + A FE L GD+ +R W KDG ++ S+ I + Sbjct: 889 PPQFKTPIQNQLDLREHAHAHFEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYV 948 Query: 1162 KLKIYDCDLDDAGEYSCEVGNS 1183 L I + DAG Y+C N+ Sbjct: 949 ALTIKQLTIYDAGTYTCRAYNA 970 Score = 39.1 bits (87), Expect = 1.3 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNN 870 + +TS + + +AE P F + V E + L A + +P + WY N Sbjct: 1938 LEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNG 1997 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 I +D + L I +E D+G Y C A N+ G++ V + K Sbjct: 1998 RPIQTGHRFKTTYDFGFVALDILYAHAE-DTGTYMCKAKNAIGEAVTTCAVNVTANK 2053 Score = 39.1 bits (87), Expect = 1.3 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 6/130 (4%) Query: 815 ETSAVITVEEPTEEN-AEPPLFINRFQEI-TVKEKGTIKLVARVTR--NPVPSITWYRNN 870 E S V T EE TEE + P+F + I ++E AR+T +P + WY N Sbjct: 3382 EYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYWNG 3441 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VT 929 + D + L I+ V E DSG+Y C A N G++ A + I ++ + Sbjct: 3442 RPLKAGSRFRTFCDFGFVILEISPVYPE-DSGEYSCRAINEYGEAVTTATMKIQGKRSII 3500 Query: 930 FVKHLQKSYE 939 L K E Sbjct: 3501 MESQLPKGME 3510 Score = 39.1 bits (87), Expect = 1.3 Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 18/198 (9%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 PP I L+ + + A E + + + L +WF I+ SN +++ K L Sbjct: 6840 PPRFIQPLEPKYFGEHEVAIIEA-IVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTL 6898 Query: 1164 KIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINF-TLRLPEFILVPANT---- 1212 I + G ++C N S T L +E + F + R E ++ P Sbjct: 6899 LIENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGE 6958 Query: 1213 DAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVL 1270 LT ++ + T V WY I + ++ T+ D++ L I + +++ +Y CV Sbjct: 6959 ALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVA 7018 Query: 1271 LD--AKSTTKLKVEVVEF 1286 + KS +K V++ F Sbjct: 7019 TNKIGKSVSKTNVKIQAF 7036 Score = 38.3 bits (85), Expect = 2.3 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 7/105 (6%) Query: 733 EPPQVIEPLKSM-IVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDT 786 + PQ I PL+ + +G++V AQV V +P + W K+ P+ A + + Sbjct: 749 QAPQFIRPLRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIFNFGY 808 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 S+ IL + +D G YT++A N G A + + I V ++ A+ Sbjct: 809 VSLNILH-LRAEDAGTYTVRAVNRIGEAISQSSIRVHSRSQVTAD 852 Score = 38.3 bits (85), Expect = 2.3 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787 + PQ L ++ +G +V L Q VG+P I W N KPVK + D Sbjct: 1289 QAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYV 1348 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ +L + D GVYT +A N G A TS + + Sbjct: 1349 ALDLLGCYAI-DSGVYTCQARNQLGEAVTSCSVRI 1382 Score = 38.3 bits (85), Expect = 2.3 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 11/128 (8%) Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD---ALVRWFK 1141 EYS + E T E P L+N + + +G A FE +T D V W+ Sbjct: 3382 EYSMVRTREETTEETK--GKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYW 3439 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI 1196 +G ++ + + D L+I +D+GEYSC E G + TA + ++ + SI Sbjct: 3440 NGRPLKAGSRFRTFCDFGFVILEISPVYPEDSGEYSCRAINEYGEAVTTATMKIQGKRSI 3499 Query: 1197 NFTLRLPE 1204 +LP+ Sbjct: 3500 IMESQLPK 3507 Score = 38.3 bits (85), Expect = 2.3 Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 27/257 (10%) Query: 159 FDSQEDESKPDVSQPPQN--IIEEAKSE---PKLIEESEQP-IAKTSEIDNEVPEKINVP 212 F +++ E KP V + P+ I++ K + P+++EE E + K EV E+ + Sbjct: 15786 FATKDSEKKPTVEELPEEQVTIQKKKKKAPVPEVVEEPEAEFLVKPKTPVQEVTEEAKIT 15845 Query: 213 DDKE-TSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271 K+ + + + +T E++ + E + E Sbjct: 15846 KSKKPVKEEEAAAELKVTITEEIPTEPEVQEIIEEIEEIEEEKPAEYVIEVKESQPEAVE 15905 Query: 272 TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331 V LPK + K+ I E + I+ +K S ++E AK+ K+ P Sbjct: 15906 DKEVSLPKKKPKAPIV-------EEPEAEITLKPKVK-----SEEVQEEAKIVKKK--PK 15951 Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYT----ITPRKS 387 K+ +V + E + E++V E E+I+E + +++ PKE PE + +K Sbjct: 15952 KIDEVAVAD-ELTVKVEEEVVPEPIVEEEVIEEFE-IKKKPKEPEPEDIVDAAIVKLKKP 16009 Query: 388 SAQKIDEIVDEVTIKKR 404 DE+V EVT+K + Sbjct: 16010 EPVDADEVVAEVTLKPK 16026 Score = 37.5 bits (83), Expect = 4.0 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALV 1137 +H ++S R E E TV P + + + +G A +E + + V Sbjct: 1801 IHQLEDHSRYQRREE--EEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKV 1858 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 WF +G + + + T D L I +D+GEY+C V N+ AI ++ Sbjct: 1859 EWFHNGKPLSTGHRFRTTYDFGFAALDILTVYAEDSGEYTCRVTNNLGEAINSI 1912 Score = 37.5 bits (83), Expect = 4.0 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%) Query: 804 TLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEIT-VKEKGTIKLVARVT--RN 859 TL A+ E I + +P EE + P+F+ + +KE L RV + Sbjct: 2059 TLDAQRLEKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPIND 2118 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P I W+ N + + D + L I V E D+G Y C A+N G++ + Sbjct: 2119 PNLKIEWFCNGKQLPTGHRYRTTHDFGYVALDILYVYGE-DTGTYICKATNQLGEAVNTC 2177 Query: 920 RVTI 923 V + Sbjct: 2178 NVRV 2181 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Query: 1107 PEIITRLQNQKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 P+ L+N KVN+G E I + V W+ +G IQ + + T D L Sbjct: 1958 PQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFVAL 2017 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILT 1190 I +D G Y C+ N+ A+ T Sbjct: 2018 DILYAHAEDTGTYMCKAKNAIGEAVTT 2044 Score = 37.1 bits (82), Expect = 5.3 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 9/121 (7%) Query: 730 GEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKSD 783 G ++ P +PL+++ + + ++ A++ VG+P + W +N K ++ + + D Sbjct: 2351 GTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHD 2410 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQE 841 S+ I +K +DEGVY +A N G A T+A + V E + + + P I+R + Sbjct: 2411 FGFVSLDISHIRK-EDEGVYMCRAVNPLGEAVTTASMRVVSEASIQMDTQHPDSISRIHQ 2469 Query: 842 I 842 + Sbjct: 2470 L 2470 Score = 37.1 bits (82), Expect = 5.3 Identities = 64/274 (23%), Positives = 108/274 (39%), Gaps = 20/274 (7%) Query: 162 QEDESKPDVSQPPQNIIEEAKS---EPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218 +ED KP V PQ ++ E K +P+ + E + +A T + V + P +E Sbjct: 5562 EEDLIKP-VQPEPQPVLWERKKKKPQPQDVIEEKLDVAPTKTYEKAVDVLPDEPKVEEKP 5620 Query: 219 QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278 + P + + K P K E E EV H + VD K P Sbjct: 5621 E-PVLWQRGKKKIP-KSEPTE-EV----HPDEVDAQIETVVKEDEMIVEEKRRIKKTKRP 5673 Query: 279 KFQLKSRIKYITSWPPESIKP-----LISYMGSIKQNGILSRNIKEAAKVK-KQVFVPPK 332 K + + P E I P + I++ R +K+ K K Q + Sbjct: 5674 KSTKEVTEELFEEQPEEEISPEEEVPQKEVIEEIEEIVEEKRRLKKTKKPKLTQQVTEEE 5733 Query: 333 LPDVEKT-ELEQPLFSYEDIVESKKDENEIIQEKQTLE-ELPKEDVPEQYTITPRKSSAQ 390 P E E E+ + E+IVE KK ++ + K E +L +E++P + T+ +++ Sbjct: 5734 TPHEEIIKESEEVVQEQEEIVEEKKKVKKVKKPKTVAEKQLKEEEIPTEETVEEEETAED 5793 Query: 391 KIDEIVDEVTIKKRLNPF-EIFYTPVEVRCGDTV 423 + + + +KK P + T VE G+ V Sbjct: 5794 QQLVVEESKKVKKVKKPTGTVEKTDVEELPGEEV 5827 Score = 37.1 bits (82), Expect = 5.3 Identities = 78/399 (19%), Positives = 160/399 (40%), Gaps = 40/399 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 P KL+ + ++ +LE ++ + +I+ KY+ + KL I Sbjct: 6536 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 6595 Query: 1077 RNTSVHDEGEYSCILRDES--CTAEVTVV-----ELPPEIITRLQ----NQKVNKGNKAT 1125 + D G Y+C ++E+ T+ ++ +PP+ L+ +K + K T Sbjct: 6596 AKVTPSDVGVYTCEAKNEAGVATSRTNIILEKEQGVPPQFTKPLKIEFIEEKQPERLKVT 6655 Query: 1126 FEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGN 1182 ++T K + V+W++ E+ S +Q+ D K L++ + ++A YS + N Sbjct: 6656 VTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQN 6715 Query: 1183 SKCTA-----ILTVEEPSINFTLRLP-----EFILVPANTDAYLTVEIPD-ETLDVTWYK 1231 A IL+ + L+ P ++VP + + +V W + Sbjct: 6716 QFGRAIGNANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMR 6775 Query: 1232 K-KSVIEDTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLDAKSTTKLKV---- 1281 + +IE+ E T+I + T I RK T + + +AKS+ + V Sbjct: 6776 NGREIIENEE--TIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQK 6833 Query: 1282 --EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 E ++ P I E +Y + + + ++ P + +W V+++ IK + Sbjct: 6834 PDEQIKPPRFIQPLEPKYFGEHEVAIIEAI-VESEPLSSFQWFVHNEPIKSSNEVRIVSQ 6892 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 + ++L I+ ++ G + R EN G V ++ Sbjct: 6893 ANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATVNLI 6931 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 529 FECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 FE ++E G ++ W + ++ S Y++ VA L I+++ DAGT+TC A Sbjct: 910 FEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYVA-LTIKQLTIYDAGTYTCRAY 968 Query: 587 NAAGFASSTTELIV 600 NA G ++ +L V Sbjct: 969 NAMGQDTTVAQLTV 982 Score = 36.7 bits (81), Expect = 7.0 Identities = 41/185 (22%), Positives = 77/185 (41%), Gaps = 15/185 (8%) Query: 1102 VVELPPEIITRLQN-QKVNKGNKATFEIEL---TKGDALVRWFKDGSEIQFSNHIQLTID 1157 VV + P +T ++ +G A FE ++ T + V WFK+G I + + D Sbjct: 1419 VVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHD 1478 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 L I +D+G Y+C N ++ +E + R E I+ +A L Sbjct: 1479 FGYVALDIVHLIAEDSGVYTCRAVN-----LIGSDETQVELQCRSGEQIVTVTQNEAGL- 1532 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 E D + Y ++ I+++ K + + + I+ E+ + + C L+ S Sbjct: 1533 -EQIHYLEDRSRYTRREEIDESTKQAPVFTTSLKNVEIK---ENQRAHFECRLIPV-SDP 1587 Query: 1278 KLKVE 1282 ++VE Sbjct: 1588 SMRVE 1592 Score = 36.7 bits (81), Expect = 7.0 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%) Query: 1107 PEIITRLQN-QKVNKGNKATFEIELT-KGDALVR--WFKDGSEIQFSNHIQLTIDGKKQK 1162 P T LQ+ K+++G E ++ + D +R WFK+G + + I+ T D Sbjct: 2622 PVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDFGLVT 2681 Query: 1163 LKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193 L I DD+ Y+C +VG + T+ L +E+ Sbjct: 2682 LSINGLRADDSAIYTCKATNQVGEAVSTSSLKIED 2716 Score = 36.3 bits (80), Expect = 9.2 Identities = 16/62 (25%), Positives = 28/62 (45%) Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 EW N K+++ + + +L + + D G Y R N G A++ N+ +D Sbjct: 3064 EWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVD 3123 Query: 1380 KP 1381 KP Sbjct: 3124 KP 3125 >UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora|Rep: Isoform B of Q9I7U4 - Drosophila melanogaster (Fruit fly) Length = 17903 Score = 830 bits (2053), Expect = 0.0 Identities = 392/769 (50%), Positives = 526/769 (68%), Gaps = 6/769 (0%) Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VAKNAAGF SSTTELIVE+PLSDHGS+ T ADILEGIPPTFSKKPKAQ Sbjct: 16007 VAKNAAGFTSSTTELIVESPLSDHGSDATALSRRSMSRESSLADILEGIPPTFSKKPKAQ 16066 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIESDMHMYCSVLKITNVK 701 YVDE ++++LECRLVA+PEPDI W F GE+I +E N+ + ESDMHMYCSV+ I+ VK Sbjct: 16067 YVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVK 16126 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 K QEGTY V+A NREGEA LPI LK++T +KE PQ++EPL++M++R+GESV+LS Q+VGN Sbjct: 16127 KSQEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGN 16186 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P P +TW K+ KPVK KSD D H++T++ P+K ++G YT+KA N G ET+A +T Sbjct: 16187 PPPKVTWYKDGKPVKN--AKSDKDLHTLTLITPQK-SEKGEYTVKAVNPLGSVETTANLT 16243 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 +EEP NAEPPLF+ RF+E V +KG I+L A+V+ NPVP + W NN + PSE I Q Sbjct: 16244 IEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQ 16303 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 +DGENIEL+I + + E DSGDYKC+ASN GK+SHGARV ++V++VTF K L+K+ E Sbjct: 16304 VYDGENIELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTFTKKLKKTITIE 16363 Query: 942 EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 E +++ LEC+TSH V+TKW+ N KE+SGMDHR ++++G+ D G C V Sbjct: 16364 EVQSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKV 16423 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 K QET + + V + P+FI+ L+D+EV EKD AIL+VE+ +E +V W +DGE I P+ Sbjct: 16424 KKQETQSTVEVLQRKPDFIKVLEDYEVTEKDTAILDVELTTEATEVTWYKDGEKITPENK 16483 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 +F K G R+L IR+ ++HDEG+Y+C + + C+ E+ V+ELPPEI+ L + V KG Sbjct: 16484 NVEFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVVIELPPEIVEPLNDVAVTKG 16543 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 A FE+EL+KGDALV+WFK+G EI F+ IQL IDGKKQ L+I +D GEYS +VG Sbjct: 16544 ENAVFEVELSKGDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVG 16603 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 A LTVEEP ++F +RLP+ L TDA TV++ ++VTW KK I+ +K Sbjct: 16604 EQTSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQK 16663 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIK 1300 + + R L+I +++D E +CV + S+TKL VE ++ PP I D ++ ++K Sbjct: 16664 HEVFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVK 16723 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 DVT V Y P P W +I K K T P+ID +SA LTIKK Sbjct: 16724 ENDDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKK 16772 Score = 176 bits (429), Expect = 5e-42 Identities = 91/279 (32%), Positives = 152/279 (54%), Gaps = 10/279 (3%) Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---- 1488 IT + +K N F V +A TT VI ++K PT+++ Sbjct: 16712 ITSDKDQTIKVKENDDVTFTVKYTG-VPTPEACWTTRKV-VIPKSKRTIPTIDEQSAKLT 16769 Query: 1489 --KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX- 1545 K++ +E ++++ L+C+FGG+P+PKVTW ++G+ ++ YENR Sbjct: 16770 IKKDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYTIEKTTIETE 16829 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y C+A N+ G ETSC + +QQKPV+ + ++ + QK + G + A + G P P V Sbjct: 16830 ATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVT 16889 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+K + + K I T E TS +K++ R S KY + A+N +GT+ VE T++V DK Sbjct: 16890 WHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDK 16949 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 PS+P+ + +++I ++S+ +EW PP+DDG + K + E Sbjct: 16950 PSRPQS-LEIKDIKKDSIVLEWTPPVDDGDEDEVKRSAE 16987 Score = 164 bits (399), Expect = 2e-38 Identities = 170/701 (24%), Positives = 299/701 (42%), Gaps = 69/701 (9%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 +LP+ K + ++ AP +E LR +G +V Q+ G P P++TW++ +K + Sbjct: 16145 RLPITLKVRTTDKE-APQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNA 16203 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 + D ++ TL + + G +T A N G +T L +E P + Sbjct: 16204 K------SDKDLHTLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAE---- 16253 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 PP F ++ + Q V + +I L ++ P P++ WLF Sbjct: 16254 -------------------PPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNTP 16294 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 + P E I + + ++K N + G Y +A N G+ S + ++ E Sbjct: 16295 LFPSERIQQVYDGENIEL--IIKDAN-PETDSGDYKCIASNPIGKTSHGARVIVEVDEVT 16351 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 + ++ K++ + + +S+ L + + T W N K + + + DG TH + Sbjct: 16352 FTKKLK--KTITIEEVQSLTLECET--SHVVTTKWFFNGKELSGMDHRVVVEDGKTHKL- 16406 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 +++ ++D G YT K + ET + + V + P FI ++ V EK T Sbjct: 16407 VIRNTNLRDSGTYTCKVKKQ----ETQSTVEVLQ------RKPDFIKVLEDYEVTEKDTA 16456 Query: 851 KLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 L +T +TWY++ E I+P ++ + DG+ LVI +V D G Y C Sbjct: 16457 ILDVELT-TEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIH-DEGQYTC--- 16511 Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEIS 968 G+ V I++ V+ L T +G+ + E + S KW+ N KEI Sbjct: 16512 KIEGQECSCELVVIELPP-EIVEPLNDVAVT-KGENAVFEVELSKGDALVKWFKNGKEIV 16569 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028 + ++ +G+ DVG V +Q + L V+E + +F+ +L D + Sbjct: 16570 FNERIQLAIDGKKQSLRIVKAKPEDVGEYSVQVGEQTSKAKLTVEEPLVDFVIRLPDITL 16629 Query: 1029 KEKDV-AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 K A V+++ +V W + G+ IKP + K++ G +R+L I + S D GE Sbjct: 16630 ATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQ-KHEVFVEGTVRRLVIHDASDEDAGEI 16688 Query: 1088 SCILRDESCTAEVTVVELP-PEIITRLQNQ--KVNKGNKATFEIELT-KGDALVRWFKDG 1143 SC+ + + + ++ V EL P +IT ++Q KV + + TF ++ T W Sbjct: 16689 SCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWTTRK 16748 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYD---CDLDDAGEYSCEVG 1181 I S TID + KL I +LD SC G Sbjct: 16749 VVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFG 16789 Score = 153 bits (372), Expect = 4e-35 Identities = 137/536 (25%), Positives = 230/536 (42%), Gaps = 69/536 (12%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 Q L D+ + + + + + + I +F +E + +P+F L+ + +G FEC Sbjct: 191 QTLRDQVDQQRIVTENIRKDIQVNSIF----TELRYASPLFTRPLKDAVSREGDRFVFEC 246 Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 +V G P P + WF+ I+ + D++ +D + LVI E F D+ F+C A N G Sbjct: 247 EVTGTPEPAVEWFKDGISIQTNSDYKTTFDK-GICRLVIEETFAADSARFSCRASNLVGT 305 Query: 592 ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 + L V ++ +E+ + +PP + ++ EGS Sbjct: 306 CDTNATLSVR----ENAAEVQL------------------VPPRILRFLQSGKATEGSSF 343 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 C + +P P + W FK ++ + D V ++ + LK V + YT Sbjct: 344 QFACVVAGVPLPTVQW-FKNDKCIDDSPDYVISYNNGE---ATLKFEEVFLEDDAVYTCS 399 Query: 712 AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A N G L ++ E E P PL + + R G+ + L A V G PRP + W Sbjct: 400 ASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLH 459 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE--PTE 827 N KP + P S + +T++ P+ D G Y L A+N G A TS + V+ P E Sbjct: 460 NGKPFQ--PRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNE 517 Query: 828 -------ENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + EP P +++++ E ++L + P P + WY N + S Sbjct: 518 TSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESAD 577 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI------------DVE 926 + F G+ L+I V E D+G YK VA NSAG++S + + E Sbjct: 578 VQLLFQGDRCSLIIQEVYQE-DAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAE 636 Query: 927 KVTFVKHLQKSYE-------TEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973 + + K Q +E +EG+ V+LE Q S ++ +W+ KE+ +D R Sbjct: 637 RQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQ-LDQR 691 Score = 144 bits (348), Expect = 3e-32 Identities = 200/791 (25%), Positives = 313/791 (39%), Gaps = 121/791 (15%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPD------------GSTVQFECQVEGYPRPQITWFRQTA 548 P E A + VE L P P G ++ E V G PRP++ W Sbjct: 403 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNG- 461 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608 KP Q Y+ V TL+I + +P DAG++ AKN AG A ++ +IV+ L + Sbjct: 462 --KPFQPRDSKYEYGRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 518 Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 S+ + A +E I P K + EG + L+C +V PEP++ W Sbjct: 519 SDSEM------------ASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWY 566 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 + ++ + + D CS++ I V + G Y VVA+N GEAS LK+ Sbjct: 567 HNERPVKESADVQLLFQGDR---CSLI-IQEVYQEDAGHYKVVAINSAGEASSSCELKVT 622 Query: 729 T-GEKEP-----------PQVIEP-----LKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 + EP P+ +P L ++ +GE V+L Q G+ T W Sbjct: 623 PLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLT 682 Query: 772 NKPVKA---LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE---- 823 NK ++ + T+SD + IL D+GVYT+K N G A+ + + V+ Sbjct: 683 NKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNA 742 Query: 824 -EPTEENAEPPLFINR-----FQEITVKEKG----TIKLVARVTRNPVPSITWYRNNEII 873 E + I R F+E+ ++G IK V P P + W+ N++ + Sbjct: 743 PENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPV 802 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTF 930 + GE L I + + G CVA N AGK++ A + I + + Sbjct: 803 HGHNFLVST-SGERQVLTIQKLTHDA-VGKISCVAENEAGKATCVAFLNIRGSGLPASSD 860 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS-------------TKWYHNKKEIS------GMD 971 V+ + + + TE + V ++ QT T S T+ +H+ I G Sbjct: 861 VQTVSQEHNTESSR-VTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQ 919 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 EI++ K Q + IP+ +L+ E+ + Sbjct: 920 RPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRR-EIAPR 978 Query: 1032 DVAILEVEINSETADVVWER--DG---EIIKPKKNKYDFEKRGHIR--------KLYIRN 1078 L +I + ADV E DG IK +KN + H R + ++ Sbjct: 979 FTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQ 1038 Query: 1079 TSVHDEGEY----SCILRDESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT- 1131 V D G Y S + + TA++ V + PP RLQ Q KG K T E+E+T Sbjct: 1039 VGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTG 1098 Query: 1132 KGDALVRWFKDGSEIQ---FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184 + V W KD ++ S H +L G +L I D+G+Y G +K Sbjct: 1099 LPEPTVTWLKDDKPLKDAGISEH-RLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAK 1157 Query: 1185 CTAILTVEEPS 1195 A + EPS Sbjct: 1158 SIADCAILEPS 1168 Score = 144 bits (348), Expect = 3e-32 Identities = 122/426 (28%), Positives = 197/426 (46%), Gaps = 42/426 (9%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--NVAT 567 P+ +E + K P+ V CQV G P P++ W+R + PS+ QM+YD+ +VA Sbjct: 8185 PLKIEFIEEKQ-PERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVAL 8243 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 VI P +A ++ A+N G A ++ E+ + Sbjct: 8244 EVINPT-PNEAVVYSVQAQNQFGRAIGNANILSRV------DEVP-------------RE 8283 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 IL+ PT + A V G + E + +P P++ W+ G EI+ EN IE+ Sbjct: 8284 ILKA--PTVTPL-SAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREII--ENEETIIETT 8338 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEK-EPPQVIEPLKS 743 + +K+ N+ + + G Y V A N+ GEA +V K E+ +PP+ I+PL+ Sbjct: 8339 ETT--TTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEP 8396 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPK-KVKDEG 801 + E I+ A V P + W +N+P+K+ + + T+L + K G Sbjct: 8397 KYFGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVG 8456 Query: 802 VYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRN 859 +T +AEN G + T+ V + + E E P F+ Q + V + + L +VT Sbjct: 8457 PFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGK 8516 Query: 860 PVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P + WY N E I+ ++ TI+Q+ G +L IT V E + G Y+CVA+N GKS Sbjct: 8517 PTPKVEWYHNAEKITENKETTISQDLQGV-CQLQITEVFPE-NEGQYECVATNKIGKSVS 8574 Query: 918 GARVTI 923 V I Sbjct: 8575 KTNVKI 8580 Score = 140 bits (339), Expect = 4e-31 Identities = 97/359 (27%), Positives = 162/359 (45%), Gaps = 15/359 (4%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L+ E ++ + + ++ + D E ++ + AP +K R +GS F +V Sbjct: 1944 LLREVSFREAITRRSGYEQDSQLSQELDRNQGPAQAPQISQKPRSSKLIEGSDAVFTARV 2003 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 P+P++TWF + SQ +++ Y VATL ++ D G +T +A+N G Sbjct: 2004 GSNPKPRLTWFHNGQRLVASQKYEISYSS-GVATLRVKNATARDGGHYTLLAENLQGCVV 2062 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653 S+ L VE P ++ E A +PP F K + + EG Sbjct: 2063 SSAVLAVE-PAAETAYEPKPVDVMAEQLEAGKA-----LPPAFVKAFGDREITEGRMTRF 2116 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVA 712 +CR+ P P++ WL G ++ D + + + ES H L ITNV + G +A Sbjct: 2117 DCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHS----LMITNVTRLDAGAVQCLA 2172 Query: 713 VNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 N+ GE ++ L + E+ PQ ++ +M VR+GE + +SA +G P+P ITW K+ Sbjct: 2173 RNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKD 2232 Query: 772 NKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + + + G T L+ +V D G Y A+N G A + VE P E+ Sbjct: 2233 GVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQ 2291 Score = 134 bits (323), Expect = 3e-29 Identities = 129/571 (22%), Positives = 241/571 (42%), Gaps = 30/571 (5%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-----ITQNFDGE 886 PP F + + V E + L R+ P P I W N E I E +T++ Sbjct: 16056 PPTFSKKPKAQYVDENTNVILECRLVAVPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHM 16115 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV---TIDVEKVTFVKHLQKSYETEEG 943 +V + + G Y+ +A+N G++ + T D E ++ L ++ EG Sbjct: 16116 YCSVVHISKVKKSQEGTYEVIATNREGEARLPITLKVRTTDKEAPQILEPL-RNMVIREG 16174 Query: 944 KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 ++V+L Q K WY + K + + + V + + Sbjct: 16175 ESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNPL- 16233 Query: 1002 KDQETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGE 1054 ET+ L ++E P F+ + ++ V +K L +++ +V W + Sbjct: 16234 GSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIRLPAKVSGNPVPEVQWLFNNT 16293 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVH-DEGEYSCILRD---ESCTAEVTVVELPPEII 1110 + P + +I +L I++ + D G+Y CI + ++ +VE+ Sbjct: 16294 PLFPSERIQQVYDGENI-ELIIKDANPETDSGDYKCIASNPIGKTSHGARVIVEVDEVTF 16352 Query: 1111 TRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 T+ + + + +E T +WF +G E+ +H + DGK KL I + + Sbjct: 16353 TKKLKKTITIEEVQSLTLECETSHVVTTKWFFNGKELSGMDHRVVVEDGKTHKLVIRNTN 16412 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 L D+G Y+C+V + + + V + +F L ++ + +T A L VE+ E +VTW Sbjct: 16413 LRDSGTYTCKVKKQETQSTVEVLQRKPDFIKVLEDYEVTEKDT-AILDVELTTEATEVTW 16471 Query: 1230 YKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288 YK + + + + I D K R L+IR T D+ +YTC + + + +L V +E PP Sbjct: 16472 YKDGEKITPENKNVEFIKDGKARRLVIRDVTIHDEGQYTCKIEGQECSCELVV--IELPP 16529 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 +IV+ + + +G + V+ +W N K I + + +ID K SL I Sbjct: 16530 EIVEPLNDVAVTKGENAVFEVELSK-GDALVKWFKNGKEIVFNERIQLAIDGKKQSLRIV 16588 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 K + D G Y +++ A + + ++D Sbjct: 16589 KAKPEDVGEYSVQVGEQTSKAKLTVEEPLVD 16619 Score = 131 bits (316), Expect = 2e-28 Identities = 104/388 (26%), Positives = 168/388 (43%), Gaps = 44/388 (11%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F +K++P + +FE + EG P P + W+R++ I+ S D Q++ + L Sbjct: 6029 APVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGK-SIL 6087 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXAD 627 +IR+VF ED+ F+CVA+N G A + L+V E + G Sbjct: 6088 IIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQ---------------- 6131 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 PP+F ++ V G + ++ D+ WL G +I P + E Sbjct: 6132 -----PPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDS 6186 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----------GEKEPPQV 737 +H L I G Y VAVN GEA +++ G ++ P + Sbjct: 6187 VH----TLLIIEPFAEDSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHI 6242 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794 +E LKS V +G VI +V G P PT W + KP + G+ + + ++ Sbjct: 6243 VEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQMSRQGEYYQL-VISE 6301 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 +DEG Y AEN G +TSA + V P EN + P I ++++V E + Sbjct: 6302 AFPEDEGTYKCVAENKLGSIQTSAQLKV-RPI-ENLDAPPTITALKDVSVTEGMPAQFKT 6359 Query: 855 RVT-RNPVPSITWYRNNEIISPSETITQ 881 VT + S+ W+R ++I + Q Sbjct: 6360 TVTGKVKATSVQWFREGQLIPETPDFQQ 6387 Score = 120 bits (288), Expect = 6e-25 Identities = 72/223 (32%), Positives = 119/223 (53%), Gaps = 18/223 (8%) Query: 301 ISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENE 360 IS G +K + + EAA K + + D E+ +E+ + ED ++ ++ E Sbjct: 15787 ISMSGKVKLKKPIKKTFSEAADEAK-IKIIQDFDDGEEPIIEE-IRDDEDTIDEVEEPEE 15844 Query: 361 IIQEKQTLEEL---------PK------EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRL 405 E+ +E+ PK ++ EQ+ I R + D +T KK+ Sbjct: 15845 YFVEELPPDEVDFKLKPKKHPKPAYSVQDEEEEQFLIGIRHPKRDSVTYDEDSLTFKKKR 15904 Query: 406 NPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEE 465 + + E + ++++ +Y+A+ +EAINLVEGE++ ++ + +WWYV+K TEE Sbjct: 15905 KVVQQLFNE-ESENLNIMYSICNYIADNNEAINLVEGEKVTVVGRHSSEWWYVKKSTTEE 15963 Query: 466 KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM 508 +GWVPAQYLM+ Y QY+Q KL+EKIDKLPVFE+ +Q + Sbjct: 15964 EGWVPAQYLMEPEEYAQYVQNKLHEKIDKLPVFERKLLPKQKV 16006 Score = 114 bits (275), Expect = 2e-23 Identities = 88/363 (24%), Positives = 162/363 (44%), Gaps = 23/363 (6%) Query: 636 FSKKPKAQYVDEGSD----ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 F+K K ++++E + + C++ P P++ W EE++P E + + + Sbjct: 8182 FTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGDV 8241 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE--PPQVIEPLKSMIVR 747 L++ N + Y+V A N+ G A + I+ ++ +E + PL +++V Sbjct: 8242 A--LEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREILKAPTVTPLSAVVVP 8299 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805 G ++ A+ G PRP + W +N + + T + T +K + K G Y + Sbjct: 8300 TGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTRKRTGKYEV 8359 Query: 806 KAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A+N G A++S +V+ ++ +E +PP FI + E + A V P+ S Sbjct: 8360 WAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSSF 8419 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923 W+ +NE I S + L+I N S+ G + C A N G + A V + Sbjct: 8420 QWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKF-VGPFTCRAENVGGSVTSTATVNLI 8478 Query: 924 ------DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREI 975 + E FV+ L + E +G+ ++L CQ + T +WYHN ++I+ I Sbjct: 8479 PQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITENKETTI 8538 Query: 976 IQE 978 Q+ Sbjct: 8539 SQD 8541 Score = 103 bits (246), Expect = 7e-20 Identities = 120/526 (22%), Positives = 212/526 (40%), Gaps = 46/526 (8%) Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 ELI + L + E T E PP ++K + + +LEC+ Sbjct: 8053 ELIEDQQLIQNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECK 8112 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + +P P+I W F + E + + + + LKI V G YT A N Sbjct: 8113 VEGVPFPEIKWYFNDILLFASEKYEITVMEQV----AKLKIAKVTPSDVGVYTCEAKNEA 8168 Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE--SVILSAQVVGNPRPTITWCKN--- 771 G A+ I G+ P IE ++ +Q E V ++ QV G P P + W + Sbjct: 8169 GVATSR--TNIILGKFTKPLKIEFIEE---KQPERLKVTVTCQVTGKPNPEVKWYRGIEE 8223 Query: 772 ---NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEEPT 826 ++ V+ + GD ++ ++ P + VY+++A+N G I + + V+E Sbjct: 8224 VIPSETVQMFYDEKTGDV-ALEVINPTP-NEAVVYSVQAQNQFGRAIGNANILSRVDEVP 8281 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDG 885 E + P + + V GT+ A+ P P + W RN EII ETI + + Sbjct: 8282 REILKAPT-VTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTE- 8339 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTID------VEKVTFVKHLQKSY 938 + + N+ + +G Y+ A N G++ S G+ V D ++ F++ L+ Y Sbjct: 8340 TTTTIKVVNMTRK-RTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKY 8398 Query: 939 ETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 E +I S +S+ +W+ + + I + I+ + VG Sbjct: 8399 FGEHEVAIIEAIVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPF 8458 Query: 998 KCIVKD---QETSTM---LVVKETI-----PEFIRKL-QDFEVKEKDVAILEVEINSE-T 1044 C ++ TST L+ +E P F+ +L Q EV + + +L ++ + T Sbjct: 8459 TCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGEALLLTCQVTGKPT 8518 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 V W + E I K + + +L I +EG+Y C+ Sbjct: 8519 PKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECV 8564 Score = 102 bits (245), Expect = 9e-20 Identities = 143/668 (21%), Positives = 262/668 (39%), Gaps = 51/668 (7%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P+ + L++ ++E + +L +I + V W +DG+ +K K+ D H L Sbjct: 16160 PQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSDKDL----HTLTLI 16215 Query: 1076 IRNTSVHDEGEYSCI----LRDESCTAEVTVVEL------PPEIITRLQNQKVNKGNKAT 1125 S ++GEY+ L TA +T+ E PP + R + Q V + + Sbjct: 16216 TPQKS--EKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKGEIR 16273 Query: 1126 FEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSC----E 1179 +++ V+W + + + S IQ DG+ +L I D + + D+G+Y C Sbjct: 16274 LPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIELIIKDANPETDSGDYKCIASNP 16333 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 +G + A + VE + FT +L + I + L E + W+ + Sbjct: 16334 IGKTSHGARVIVEVDEVTFTKKLKKTITIEEVQSLTLECET-SHVVTTKWFFNGKELSGM 16392 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299 + ++ D K L+IR D YTC + K T+ VEV++ P + +Y + Sbjct: 16393 DHRVVVEDGKTHKLVIRNTNLRDSGTYTCKV--KKQETQSTVEVLQRKPDFIKVLEDYEV 16450 Query: 1300 KRGSDVTLLVDYQAFPQPND-EWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 T ++D + + + W + KI + K+ + D K+ L I+ V D G Sbjct: 16451 TEKD--TAILDVELTTEATEVTWYKDGEKITPENKNVEFIKDGKARRLVIRDVTIHDEGQ 16508 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 Y ++E + + +++ P +P + ++ + E E + ++ + Sbjct: 16509 YTCKIEGQ----ECSCELVVIELPPEIVEP-LNDVAVTKGENAVFEVELSKGDALVKWFK 16563 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +EI E I + K Q S++ +K V E + +T++ ++E Sbjct: 16564 NGKEIVFNERIQLAIDGKKQ-SLRIVKAKPE------DVGEYSVQVGEQTSKAKLTVEEP 16616 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRX 1533 + + P + T+ D E T P +VTW + GK +K + Sbjct: 16617 LVDF-VIRLPDITLATKTT-DAEFTVQLSQ-PDVEVTWCKKGKPIKPNQKHEVFVEGTVR 16673 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 C+A N + CV ++ PVIT S++D K K D+ T Sbjct: 16674 RLVIHDASDEDAGEISCVAENVTSSTKL-CVEELKLPPVIT-SDKDQTIKVKENDDVTFT 16731 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 G+P PE W + K T E+++ + IK+ S K + G Sbjct: 16732 VKYTGVPTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFGGI 16791 Query: 1654 SSVEVTLK 1661 +VT K Sbjct: 16792 PEPKVTWK 16799 Score = 101 bits (243), Expect = 2e-19 Identities = 111/458 (24%), Positives = 194/458 (42%), Gaps = 54/458 (11%) Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQ-----EGTYTVVAVNREG---EASLPIVLKI 727 P +N+ I S+ + Y S+ + V F+ E ++ R G ++ L L Sbjct: 1913 PIQNLEKNIYSNGYSYTSIEEEFRVDTFEYRLLREVSFREAITRRSGYEQDSQLSQELDR 1972 Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787 G + PQ+ + +S + +G + +A+V NP+P +TW N + + A + Sbjct: 1973 NQGPAQAPQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSS 2032 Query: 788 SITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE---------EPTEENAE----- 831 + L+ K +D G YTL AEN +G +SAV+ VE +P + AE Sbjct: 2033 GVATLRVKNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAG 2092 Query: 832 ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGE 886 PP F+ F + + E + RVT NP P + W N + S I N G Sbjct: 2093 KALPPAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGS 2152 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQK--SYETEEG 943 + L+ITNV + +D+G +C+A N AG+ + A++ + + E+V + +Q+ + EG Sbjct: 2153 H-SLMITNV-TRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREG 2210 Query: 944 KTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 + + + T + W + +IS R + +G D G +C Sbjct: 2211 EPITMSANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTA 2270 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 ++ ST + + E R+ ++E + ++ R ++I+P Sbjct: 2271 QNIAGSTANRARLYV-EVPREQPNYEQRRLNL----------------PRPTKVIEPGAR 2313 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 K G I L + + HD GEY C + + S AE Sbjct: 2314 ATSVFKFGFI-ALDLLSIMGHDSGEYMCRVTNASGVAE 2350 Score = 99.1 bits (236), Expect = 1e-18 Identities = 147/637 (23%), Positives = 240/637 (37%), Gaps = 90/637 (14%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F++ K EG + EC + PEP + W G I + + + + C Sbjct: 225 PLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGI---CR 281 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQG 749 L I ++ A N G L ++ E PP+++ L+S +G Sbjct: 282 -LVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEG 340 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 S + V G P PT+ W KN+K + P + LK ++V +D+ VYT A Sbjct: 341 SSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSA 400 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N GI SA + V EP E E P F + IKL A V P P + W Sbjct: 401 SNPAGIEHCSASLIV-EPLEP-TELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 458 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923 N + P ++ ++ + L+I D+G Y A N AG++ V + Sbjct: 459 HNGKPFQPRDS---KYEYGRVTLIIPQAYPN-DAGSYVLSAKNLAGEAYTSCNVIVKGRL 514 Query: 924 -----------DVEKVTFVKHLQ-KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969 D+E + HL K EGK V L+C + WYHN++ + Sbjct: 515 PNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKE 574 Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCI------------------VKDQETST--- 1008 +++ +G D G K + + E +T Sbjct: 575 SADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQ 634 Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVW-ERDGEIIKPKKNKY 1063 + K++ P+F R L D E + +LEV+ + + W + E+ ++ Sbjct: 635 AERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITT 694 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV--VELPP---------E 1108 + + KL + N S D+G Y+ + D C + + V V P E Sbjct: 695 QSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVE 754 Query: 1109 IITRLQNQKVNK--GNKATFEIELTKGDALVR--------WFKDGSEIQFSNHIQLTIDG 1158 II R Q + + +K E+ K + +V+ WF + + N + ++ G Sbjct: 755 IIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFL-VSTSG 813 Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191 ++Q L I D G+ SC E G + C A L + Sbjct: 814 ERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNI 850 Score = 95.1 bits (226), Expect = 2e-17 Identities = 99/384 (25%), Positives = 156/384 (40%), Gaps = 43/384 (11%) Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEK---PTSEEQSMAPIFVEKLRPK-HTP-- 522 +P Y D +Y + E V K P S +E ++P H P Sbjct: 480 IPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLK 539 Query: 523 -----DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 +G V+ +C + G P P++ W+ +K S D Q+ + D +L+I+EV+ ED Sbjct: 540 DVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDR-CSLIIQEVYQED 598 Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 AG + VA N+AG ASS+ EL V PL+ + + P F Sbjct: 599 AGHYKVVAINSAGEASSSCELKV-TPLNQ--------AEPATRAQAERQSLPKDSQPKFE 649 Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 + DEG ++LE + W +E+ D+ I+ +S++ ++ +L Sbjct: 650 RLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLIL-- 707 Query: 698 TNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGE-----KEPPQVIE-----PLKSM 744 NV +G YTV N G+A S IV + E + ++IE K + Sbjct: 708 NNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKEL 767 Query: 745 IV-RQGE--SVI-LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798 +QGE VI V G P P + W N++PV + G+ +TI K Sbjct: 768 FSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTH-D 826 Query: 799 DEGVYTLKAENSEGIAETSAVITV 822 G + AEN G A A + + Sbjct: 827 AVGKISCVAENEAGKATCVAFLNI 850 Score = 95.1 bits (226), Expect = 2e-17 Identities = 81/306 (26%), Positives = 125/306 (40%), Gaps = 22/306 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+KK + V E E P P + W E P +N S ++ S Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWY---RESFPIQN-SPDLQIHTFSGKS 6085 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT------GEKEPPQVIEPLKSMIVR 747 +L I V ++ VA NR G A L ++ G +PP + ++S V Sbjct: 6086 ILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVA 6145 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTK--SDGDTHSITILKPKKVKDEGVYT 804 G+ A+V G + W KN ++ ++ K + H++ I++P +D G Y Sbjct: 6146 TGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPF-AEDSGRYE 6204 Query: 805 LKAENSEGIAETSAVITV------EEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVT 857 A N+ G A V E+PT +E P + + + TV+E + RV Sbjct: 6205 CVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVD 6264 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P+ W R + PS + GE +LVI+ E D G YKCVA N G Sbjct: 6265 GKPTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPE-DEGTYKCVAENKLGSIQT 6323 Query: 918 GARVTI 923 A++ + Sbjct: 6324 SAQLKV 6329 Score = 85.0 bits (201), Expect = 2e-14 Identities = 45/115 (39%), Positives = 64/115 (55%), Gaps = 2/115 (1%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 EKPT+ AP VE+L+ + +GS V F C+V+G P P W R +KPS+ FQM Sbjct: 6229 EKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMRGENFVKPSRYFQM 6288 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 + LVI E FPED GT+ CVA+N G ++ +L V P+ + + T+ Sbjct: 6289 SRQGE-YYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQLKVR-PIENLDAPPTI 6341 Score = 85.0 bits (201), Expect = 2e-14 Identities = 125/637 (19%), Positives = 252/637 (39%), Gaps = 42/637 (6%) Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 + +++G+ Q L+ +++ E S E+ T + E+ F + + I + Sbjct: 7944 EASVEGQPQLLEAAIAEIEKVDEISQEISQKTITLLKKTEDTRPQF-ITTEQLIELDVE- 8001 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCVL 1270 D +E+ + + K++ V++D++ + + ++ + I K +++ E ++ Sbjct: 8002 DVRRDLEMKVTSNIIKKEKRRVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLI 8061 Query: 1271 LDAKSTTKLKV-----EVVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319 + + TT +V ++V+ PP+I + R + L + P P Sbjct: 8062 QNQQETTTSEVIGQERKLVKKKKKEIKPPRITEKLRPRQCVPEEPTVLECKVEGVPFPEI 8121 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +W N ++ + + ++ + A L I KV +D G+Y +N G A N+ IL Sbjct: 8122 KWYFNDILLFASEKYEITVMEQVAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNI-ILG 8180 Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTG--NSTIIYY--VVEYQEIDTTEWISVKNITK 1435 K + P K +E + TG N + +Y + E +T + + Sbjct: 8181 KFTKPLKIEFIEEKQPERLKVTVTCQVTGKPNPEVKWYRGIEEVIPSETVQMFYDEKTGD 8240 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 + N N + + A N+ I +A+ + +V +E +++PTV PL + Sbjct: 8241 VALEVINPTPNEAVVYSVQAQNQFGRAIGNANILSRVDEVPREI-LKAPTV-TPLSAVVV 8298 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549 + + G+P+P+V W R+G+++ +T T E Y+ Sbjct: 8299 PTGGTLFFEAKYDGLPRPEVKWMRNGREIIENEETIIETTETTTTIKVVNMTRKRTGKYE 8358 Query: 1550 CIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKVGDE-WLVTAVIEGIPPPE 1603 A N GE ++S VV QKP I + ++ K+ E ++ A++E P Sbjct: 8359 VWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPLSS 8418 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661 W+ + +++ E I ++ S + I+ + +T A N G TS+ V L Sbjct: 8419 FQWFVHNEPIKSSNEVRIVSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATVNLI 8478 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 ++ + E P + E+ ++ +D L LT K P + + Sbjct: 8479 PQEEAEEFESPRFVEEL------VQPVEVMDGEALLLTCQVTGKPTPKVEWYHNAEKITE 8532 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 + ET Q L C+ + G E + + I Sbjct: 8533 NKETTISQDLQGVCQLQITEVFPENEGQYECVATNKI 8569 Score = 79.8 bits (188), Expect = 8e-13 Identities = 87/339 (25%), Positives = 141/339 (41%), Gaps = 40/339 (11%) Query: 512 FVEKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 FV +L P T T E V+ P ++TW ++ IKP+Q +++ + V LVI Sbjct: 16620 FVIRL-PDITLATKTTDAEFTVQLSQPDVEVTWCKKGKPIKPNQKHEVFVEG-TVRRLVI 16677 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL--SDHGSEMTVXXXXXXXXXXXXADI 628 + EDAG +CVA+N E + P+ SD + V + Sbjct: 16678 HDASDEDAGEISCVAENVTSSTKLCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGV 16737 Query: 629 LEG----------IP------PTFSKKP-----KAQYVDE-GSDILLECRLVAIPEPDIA 666 IP PT ++ K V E ++ L C IPEP + Sbjct: 16738 PTPEACWTTRKVVIPKSKRTIPTIDEQSAKLTIKKDVVSELDKEVTLSCVFGGIPEPKVT 16797 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 W G+ E+ S+ E+ + Y ++ T ++ E TYT VA N +G A LK Sbjct: 16798 WKKNGQVF---ESRSIRYENRVAKY--TIEKTTIET--EATYTCVATNEKGSAETSCRLK 16850 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK---NNKPVKALPTKSD 783 ++ +K +V + + +R G + + A V G P+PT+TW K K K++ ++ Sbjct: 16851 LQ--QKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWHKETIEQKTTKSVTIETT 16908 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 T + T+ K + + G Y + A N G + V Sbjct: 16909 ETTSTYTVKKVTR-EQSGKYKVTATNESGTTYVECTVQV 16946 Score = 79.0 bits (186), Expect = 1e-12 Identities = 51/205 (24%), Positives = 100/205 (48%), Gaps = 11/205 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P F+ + VD+G+D+ +E P P+I G ++ D + ++ + + Sbjct: 975 IAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNR--- 1031 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +++ V G Y V A N G+++ L +K PP L++ + ++GE Sbjct: 1032 -VTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKK-TIFPPVFGRRLQAQVSKKGEK 1089 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVYTLK 806 + + +V G P PT+TW K++KP+K + G+++ + I++ + D G Y ++ Sbjct: 1090 LTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL-IIEKAQTTDSGKYMVR 1148 Query: 807 AENSEGIAETSAVITVEEPTEENAE 831 A N+ G A++ A + EP+ E + Sbjct: 1149 ATNAGGEAKSIADCAILEPSPERLQ 1173 Score = 79.0 bits (186), Expect = 1e-12 Identities = 52/186 (27%), Positives = 84/186 (45%), Gaps = 6/186 (3%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 VTW K V E + + V K T I K T + + YTCV + K + + + Sbjct: 16796 VTWKKNGQVFE-SRSIRYENRVAKYT--IEKTTIETEATYTCVATNEKGSAETSCRLKLQ 16852 Query: 1287 PPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 +++ E +Y +++ GS +T+ + +PQP W + K K ++ Sbjct: 16853 QKPVLEVEDKYLTQKLRTGSILTIPATVRGYPQPTVTWHKETIEQKTTKSVTIETTETTS 16912 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 + T+KKV +G YK+ N G VE V ++DKPS P I +I SI + W Sbjct: 16913 TYTVKKVTREQSGKYKVTATNESGTTYVECTVQVIDKPSRPQSLEIKDIKKDSIVLEWTP 16972 Query: 1404 PENTGN 1409 P + G+ Sbjct: 16973 PVDDGD 16978 Score = 76.2 bits (179), Expect = 9e-12 Identities = 75/323 (23%), Positives = 131/323 (40%), Gaps = 35/323 (10%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P ++Q +V + +A FE+E + + V+W+++ IQ S +Q+ K L I Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTFSGKSILII 6089 Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEP--SINFTLRLPEFILVPANT------- 1212 ++D+ +SC G +KC+A L VEE + ++ P F+ +T Sbjct: 6090 RQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVATGQL 6149 Query: 1213 ---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 DA +T P LDV W K I+ + KF ++ + TL+I + +D Y CV Sbjct: 6150 ARFDAKVTGTRP---LDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 6206 Query: 1270 LLDAKSTTKLKVE-VVEFP--------------PKIVDYEREYRIKRGSDVTLLVDYQAF 1314 ++A + + +V+ P P IV+ + ++ GS V Sbjct: 6207 AVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVIFRCRVDGK 6266 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W+ +K ++ + S + L I + D G YK EN G Sbjct: 6267 PTPTARWMRGENFVKPSRYFQMSRQGEYYQLVISEAFPEDEGTYKCVAENKLGSIQTSAQ 6326 Query: 1375 VTILDKPSPPGKPNILEIDSSSI 1397 + + + P I + S+ Sbjct: 6327 LKVRPIENLDAPPTITALKDVSV 6349 Score = 76.2 bits (179), Expect = 9e-12 Identities = 76/249 (30%), Positives = 125/249 (50%), Gaps = 21/249 (8%) Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEES-EQPIAKTSEIDNEVPEKINVPDDKETS 218 ++ ED +KP S+ + + ++ +LI++ EQ I KT + E EKI K+ Sbjct: 14267 ETVEDVTKPK-SKKKKVVKKKTDDHDELIKKMLEQEIEKT---ELEKYEKIEFDVPKKLK 14322 Query: 219 QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278 + + L PIKIERKE + + + D P+ E + V+LP Sbjct: 14323 P------EFAALEPIKIERKEQKPTKVTILDATDVPKTVKLKPSKRKEKPAEELT-VQLP 14375 Query: 279 KFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVE- 337 KF+LK+R+ + +PP + P + +G+IK NG LSRNI+EA ++ K F P K ++ Sbjct: 14376 KFRLKARM-VLVEYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILK--FKPHKTKKIKK 14432 Query: 338 -KTELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQ-KID 393 K +LE+ L YE + S+++ E K+ E+ PK E+ E + K + K + Sbjct: 14433 IKDDLEKVELEKYEKYISSEEEPEEKTPYKKP-EKAPKPEEKQEDVKLKLGKGKKKPKEE 14491 Query: 394 EIVDEVTIK 402 E + VT+K Sbjct: 14492 EAPENVTLK 14500 Score = 75.8 bits (178), Expect = 1e-11 Identities = 87/403 (21%), Positives = 157/403 (38%), Gaps = 30/403 (7%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P+P EW + I+ K + D L I++ D+ + R N G D Sbjct: 252 PEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNAT 311 Query: 1375 VTILDKPS-----PPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTE 1426 +++ + + PP L+ ++ + T+ ++ + D+ + Sbjct: 312 LSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPD 371 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 ++ N + + + + A N I S + + ++ T++ P+ + Sbjct: 372 YVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL-IVEPLEPTEL--PSFKV 428 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXX 1545 PL N + I+L I GG+P+P+V W +GK + + YE R Sbjct: 429 PLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDA 488 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQK-PVITISNE---DIKQ-KHKV-----------GDE 1589 Y A N GE TSC V ++ + P T +E DI+ K V G Sbjct: 489 GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKP 548 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + VI G P PEVIWY N ++ + + + + I+E+ + + Y + A N Sbjct: 549 VRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAIN 608 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 +AG +S LKV P P + R+S+ + +P + Sbjct: 609 SAGEASSSCELKV--TPLNQAEPATRAQAERQSLPKDSQPKFE 649 Score = 73.3 bits (172), Expect = 7e-11 Identities = 73/280 (26%), Positives = 127/280 (45%), Gaps = 19/280 (6%) Query: 335 DVEKTELEQPLFSYEDIV--ESKKDENEIIQEKQT--LEELPKEDVPEQYTITPRKSSAQ 390 DV+ + + + E++V E + + +K+T L+E E P+ + + + Sbjct: 7905 DVKVVAVSEDVLPEEEVVPTEETPEAKQKAHKKRTKRLKEASVEGQPQ--LLEAAIAEIE 7962 Query: 391 KIDEIVDEV-----TIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGE-R 444 K+DEI E+ T+ K+ + E V V + E N+++ E R Sbjct: 7963 KVDEISQEISQKTITLLKKTEDTRPQFITTEQLIELDVEDVRRDL-EMKVTSNIIKKEKR 8021 Query: 445 LYILDTSN---QDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKP 501 +LD S + QK + E V + L+++ Q Q+ ++ Sbjct: 8022 RVVLDDSQPLPELELITQKRIQEGIDKVADEELIEDQQLIQNQQETTTSEVIGQERKLVK 8081 Query: 502 TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 +++ P EKLRP+ P+ TV EC+VEG P P+I W+ ++ S+ +++ Sbjct: 8082 KKKKEIKPPRITEKLRPRQCVPEEPTV-LECKVEGVPFPEIKWYFNDILLFASEKYEITV 8140 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + VA L I +V P D G +TC AKN AG A+S T +I+ Sbjct: 8141 MEQ-VAKLKIAKVTPSDVGVYTCEAKNEAGVATSRTNIIL 8179 Score = 71.3 bits (167), Expect = 3e-10 Identities = 88/343 (25%), Positives = 148/343 (43%), Gaps = 30/343 (8%) Query: 83 EPAVVKLPKFQLKSRIKFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXX-----XX 137 E V+LPKF+LK+R+ + ++PP + P T +G+IK NGELSRN++EA Sbjct: 14368 EELTVQLPKFRLKARMVLV-EYPPAPLIPKTTDIGAIKDNGELSRNIEEAEEILKFKPHK 14426 Query: 138 XXXXXXXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAK 197 DLE+V LEK + + S E+E P+ P + + K E K E+ + + K Sbjct: 14427 TKKIKKIKDDLEKVELEKYEKYISSEEE--PEEKTPYKKPEKAPKPEEKQ-EDVKLKLGK 14483 Query: 198 TSE--IDNEVPEKINVPDDKETSQTPTSFNKRSKL--TPIKIERKEMEVSTPQHAETVDG 253 + + E PE + + K Q P + +L P ++E E + P+ E V Sbjct: 14484 GKKKPKEEEAPENVTL---KNIPQKPQEVEEEVELKQKPKEVEIVEEQTKKPKDGEFVVE 14540 Query: 254 PQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGIL 313 P E ++ P+ K + T + P+ S +I + Sbjct: 14541 P--FEPSEFDRPEYVPDELEQIEHPEIPEKVKKPSKTKYKPKDKSK--SEPETIVSEIVA 14596 Query: 314 SRNIKEAAKVKKQV-FVPPKLPDVEKTELEQPLFSYEDIVESKKDEN---EIIQEKQTLE 369 +E A ++ V F P+ E+T+ E L + ++ KDEN + + + E Sbjct: 14597 GVPKEEEAIPEQDVKFRKPERDAPEETDSEIKL---RPVPQASKDENPDEQALVTPKAEE 14653 Query: 370 ELPK--EDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEI 410 +P+ ED P+KS +K+ E+ K+ FE+ Sbjct: 14654 PIPQEIEDKAIDDEKKPKKSKPKKVQPKEQEIA-KEEPEEFEV 14695 Score = 70.9 bits (166), Expect = 4e-10 Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 12/207 (5%) Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATY 1529 + E + SP +PLK+ + + C G P+P V W++DG ++T K T+ Sbjct: 216 IFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTF 275 Query: 1530 ENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQ----- 1582 + + C A N G +T+ + +++ + + I + Sbjct: 276 DKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSG 335 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + V+ G+P P V W+KN +++ +Y I+ + ++ +E+ + Sbjct: 336 KATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 395 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKP 1669 YT ASN AG +L V +P +P Sbjct: 396 YTCSASNPAGIEHCSASLIV--EPLEP 420 Score = 69.7 bits (163), Expect = 8e-10 Identities = 93/408 (22%), Positives = 171/408 (41%), Gaps = 39/408 (9%) Query: 1001 VKDQETSTMLVVKETIPEF---IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 +++Q T L ++ E I+ L+D +E++V + I E + E + I + Sbjct: 111 IREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQN--IRDEETRIRREEEERIRR 168 Query: 1058 PKKNKYDFEKRGHIRKLYI-RNTSVHDEGEYSCIL-----RDESCTAEVTVVELPPEIIT 1111 +++ E+ I++ I R ++ D+ + I+ +D + T + + T Sbjct: 169 ENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFT 228 Query: 1112 R-LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 R L++ +G++ FE E+T + V WFKDG IQ ++ + T D +L I + Sbjct: 229 RPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETF 288 Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTL---RLPEFILVPANTD------AYL 1216 D+ +SC VG A L+V E + L R+ F+ T+ A + Sbjct: 289 AADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACV 348 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS- 1275 +P T V W+K I+D+ + + + + TL + +D YTC + Sbjct: 349 VAGVPLPT--VQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGI 406 Query: 1276 ---TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + L VE +E P ++ ++ + G + L P+P W+ N K + Sbjct: 407 EHCSASLIVEPLE-PTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQ 465 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + +K + +L I + DAG Y L +N G A NV + Sbjct: 466 P-RDSK--YEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIV 510 Score = 69.7 bits (163), Expect = 8e-10 Identities = 89/363 (24%), Positives = 145/363 (39%), Gaps = 57/363 (15%) Query: 520 HTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 +T +G FEC++E P ++ WF+ I F+ +D VA L I + ED Sbjct: 3071 NTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHDFGYVA-LDIVHLIAED 3129 Query: 578 AGTFTCVAKNAAGFASSTTEL-------IVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630 +G +TC A N G + EL IV ++ G E + +I E Sbjct: 3130 SGVYTCRAVNLIGSDETQVELQCRSGEQIVTVTQNEAGLEQ-IHYLEDRSRYTRREEIDE 3188 Query: 631 GIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIES 686 P F+ K + E ECRL+ + +P + W +P ++ S E+ Sbjct: 3189 STKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNN---LPLKSGSRFTET 3245 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG----------------------EASLPIV 724 + + + L I + GTYT A N G E +LP + Sbjct: 3246 NNFGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRL 3304 Query: 725 LKIKTGEK------------EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCK 770 ++ G K + P P++ + V + ++V A++ VG+P+ T+ W + Sbjct: 3305 QHLEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLR 3364 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 N +P++A + L K V +D G YT +A N G A TSA + V+ T Sbjct: 3365 NGQPIEASNRTTTMHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSI 3424 Query: 829 NAE 831 E Sbjct: 3425 QLE 3427 Score = 69.7 bits (163), Expect = 8e-10 Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 22/262 (8%) Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQ 540 L+K N + + E+ T E + AP+F L ++ +G FE ++ P+ + Sbjct: 5011 LEKIANLEYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLK 5070 Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + W+ +K F+ + D V L I V+PED+G ++C A N G A +T + + Sbjct: 5071 VEWYWNGRPLKAGSRFRTFCDFGFVI-LEISPVYPEDSGEYSCRAINEYGEAVTTATMKI 5129 Query: 601 EAPLS-------DHGSEMTVXXXXXXXXXXXXA-----DILEGIPPTFSKKPKAQYVDEG 648 + S G E T+ + D G PP F P + E Sbjct: 5130 QGKRSIIMESQLPKGMEGTIDRIAELEGLGSRSTEFVPDDDTGKPPEFITSPFDMVIGEN 5189 Query: 649 SDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 + ECRL I +P + W G+ + I +D +L+I + G Sbjct: 5190 ALAHFECRLQPINDPSMRVDWFHNGKALWAGSRIKTI--NDFGFV--ILEIAGCYQRDSG 5245 Query: 707 TYTVVAVNREGEASLPIVLKIK 728 YT A N+ GEA++ L++K Sbjct: 5246 LYTCKATNKHGEATVSCKLQVK 5267 Score = 69.3 bits (162), Expect = 1e-09 Identities = 94/422 (22%), Positives = 166/422 (39%), Gaps = 53/422 (12%) Query: 774 PVKALPTKSDGDTHS--ITILKPKKVKDEGVYTLKAENSEGIAETSAVI---TVEEPTEE 828 P K + S+ H + + K ++V+ E L+ ET+ V T++E + Sbjct: 5962 PPKGIAQPSESSVHGREVHMNKQQQVQKEIQGDLEITRKITATETTEVEHKGTIQERVVQ 6021 Query: 829 N----AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNF 883 A+ P+F + Q V E K P P++ WYR + I S + F Sbjct: 6022 GPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRESFPIQNSPDLQIHTF 6081 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHL 934 G++I L+I V E DS + CVA N G + A + ++ ++ +FV + Sbjct: 6082 SGKSI-LIIRQVFVE-DSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTI 6139 Query: 935 QKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 Q S G+ + + + T + W N +I ++++E Sbjct: 6140 Q-STTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAE 6198 Query: 993 DVGVIKCIVKDQETSTML----VVK-------------ETIPEFIRKLQDFEVKEKDVAI 1035 D G +C+ + +V+ E P + +L+ V+E I Sbjct: 6199 DSGRYECVAVNAAGEARCDGDCIVQSPSKPEKPTTPGSEKAPHIVEQLKSQTVEEGSKVI 6258 Query: 1036 LEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 ++ + T W R +KP + + ++G +L I DEG Y C+ ++ Sbjct: 6259 FRCRVDGKPTPTARWMRGENFVKPSRY-FQMSRQGEYYQLVISEAFPEDEGTYKCVAENK 6317 Query: 1095 ------SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELT-KGDAL-VRWFKDGS 1144 S +V +E P IT L++ V +G A F+ +T K A V+WF++G Sbjct: 6318 LGSIQTSAQLKVRPIENLDAPPTITALKDVSVTEGMPAQFKTTVTGKVKATSVQWFREGQ 6377 Query: 1145 EI 1146 I Sbjct: 6378 LI 6379 Score = 69.3 bits (162), Expect = 1e-09 Identities = 66/250 (26%), Positives = 101/250 (40%), Gaps = 26/250 (10%) Query: 480 YTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538 Y + + K+ E K V +EQ P F++ L PK+ + E VE P Sbjct: 8357 YEVWAKNKVGEAKSSGSVVVSDQKPDEQIKPPRFIQPLEPKYFGEHEVAIIEAIVESEPL 8416 Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598 WF IK S + ++ N +TL+I + G FTC A+N G +ST + Sbjct: 8417 SSFQWFVHNEPIKSSNEVRI-VSQANKSTLLIENFQSKFVGPFTCRAENVGGSVTSTATV 8475 Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 + P + A+ E P + + V +G +LL C++ Sbjct: 8476 NL-IPQEE-------------------AEEFES-PRFVEELVQPVEVMDGEALLLTCQVT 8514 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 P P + W E+I EN I D+ C L+IT V EG Y VA N+ G+ Sbjct: 8515 GKPTPKVEWYHNAEKIT--ENKETTISQDLQGVCQ-LQITEVFPENEGQYECVATNKIGK 8571 Query: 719 ASLPIVLKIK 728 + +KI+ Sbjct: 8572 SVSKTNVKIQ 8581 Score = 68.5 bits (160), Expect = 2e-09 Identities = 107/435 (24%), Positives = 174/435 (40%), Gaps = 55/435 (12%) Query: 996 VIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053 V + I KD Q S ++ P F R L+D +E D + E E+ V W +DG Sbjct: 203 VTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDG 262 Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-------- 1102 I+ + K F+K I +L I T D +SC + +C T+ Sbjct: 263 ISIQTNSDYKTTFDKG--ICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAE 320 Query: 1103 VEL-PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159 V+L PP I+ LQ+ K +G+ F + G L V+WFK+ I S ++ + Sbjct: 321 VQLVPPRILRFLQSGKATEGSSFQFAC-VVAGVPLPTVQWFKNDKCIDDSPDYVISYNNG 379 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVE--EPSINFTLRLPEFILVPANTD 1213 + LK + L+D Y+C N C+A L VE EP+ LP F + +N Sbjct: 380 EATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPT-----ELPSFKVPLSNAM 434 Query: 1214 AYLTVEIPDETL-------DVTWYKKKSVIEDTE------KFTLI------SDVKKRTLI 1254 A + +I E + +V W + + + TLI +D L Sbjct: 435 ARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLS 494 Query: 1255 IRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 + + + L + S +++ ++ P + ++ I G V L Sbjct: 495 AKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCV 554 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA- 1369 P+P W N + +K+ + SL I++V DAG YK+ N+ G A Sbjct: 555 IVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEAS 614 Query: 1370 -DVEMNVTILDKPSP 1383 E+ VT L++ P Sbjct: 615 SSCELKVTPLNQAEP 629 Score = 68.1 bits (159), Expect = 2e-09 Identities = 84/354 (23%), Positives = 145/354 (40%), Gaps = 29/354 (8%) Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 ++ T ++P + +PL+N+ E + L+ G P PKVTWY+DGK +K AK+ ++ Sbjct: 16152 VRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKNAKSD-KDLH 16210 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVITISNEDIKQKHKVG 1587 Y A N G VET+ + I++ +P + + + + + G Sbjct: 16211 TLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLFVERFEEQNVPQKG 16270 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 E + A + G P PEV W N L +++ + E +I + S Y Sbjct: 16271 -EIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIELIIKDANPETDSGDYKCI 16329 Query: 1647 ASNTAGTSS------VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 ASN G +S VEV + K K + + + E+ +S+T+E + + TK Sbjct: 16330 ASNPIGKTSHGARVIVEVDEVTFTK--KLKKTITIEEV--QSLTLE----CETSHVVTTK 16381 Query: 1701 YAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 + E + + V D L ++ Y +V Q E L+ +P Sbjct: 16382 WFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKKQETQSTVEVLQRKPDF 16441 Query: 1760 IKTALDVP-SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK-VEIKQEGK 1811 IK D + + E+ +TW+ K+G + K VE ++GK Sbjct: 16442 IKVLEDYEVTEKDTAILDVELTTEATEVTWY---KDGEKITPENKNVEFIKDGK 16492 Score = 66.5 bits (155), Expect = 8e-09 Identities = 61/269 (22%), Positives = 106/269 (39%), Gaps = 20/269 (7%) Query: 498 FEKPTSEEQSM--APIFVEKL-RPKHTPDGSTVQFECQVEGYPRP--QITWFRQTAIIKP 552 +++ EE ++ AP+FV KL P + +G + +EC++E YP P ++ WF + Sbjct: 3446 YQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKPLST 3505 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--------SSTTELIVEAPL 604 F+ YD A L I V+ ED+G +TC N G A +S + +I E Sbjct: 3506 GHRFRTTYDF-GFAALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNVTSRSSIIHETQH 3564 Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP- 663 + +++ + P F + + V+EG+ + LE L+ + +P Sbjct: 3565 EEALTKIQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPT 3624 Query: 664 -DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722 + W G I + L I GTY A N GEA Sbjct: 3625 MKVEWYCNGRPIQTGHRFKTTYDFGF----VALDILYAHAEDTGTYMCKAKNAIGEAVTT 3680 Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + + + ++ + +RQ E+ Sbjct: 3681 CAVNVTANKTLDLDTLDAQRLEKIRQLET 3709 Score = 65.7 bits (153), Expect = 1e-08 Identities = 67/257 (26%), Positives = 105/257 (40%), Gaps = 24/257 (9%) Query: 481 TQYLQKKLNEKIDKLP--VFEKPTSEEQSMA---PIFVEKLR-PKHTPDGSTVQFECQVE 534 T + + L EK L F +P + + ++ P+FV L PK DG + EC++E Sbjct: 2760 TSSMHRGLYEKTQNLENKPFVEPQYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLE 2819 Query: 535 --GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 G P ++ WF + F+ YYD VA +I+ D+G +T A N G A Sbjct: 2820 PMGDPTMRVEWFHNGRPVTVGSRFRTYYDFGFVALDIIKAT-AADSGEYTVRATNHLGTA 2878 Query: 593 SST--------TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 ++ T+++ E ++ E DI P F++ Sbjct: 2879 HTSACVRVIDHTDVVTETQ-NEQSLEQIQLLEDSRRRHHQEEDITIMQAPQFTRGLHNIE 2937 Query: 645 VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 EG+++ LECRL + +P I W G+ + A E D Y + L + Sbjct: 2938 TIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFD---YVA-LDLLGCYA 2993 Query: 703 FQEGTYTVVAVNREGEA 719 G YT A N+ GEA Sbjct: 2994 IDSGVYTCQARNQLGEA 3010 Score = 65.3 bits (152), Expect = 2e-08 Identities = 93/376 (24%), Positives = 150/376 (39%), Gaps = 56/376 (14%) Query: 496 PVFEKPTSEEQSMA-PIFVEKLR-PKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIK 551 P+ +PT E+ PIF + L P +G+ FE +V G P + WF ++ Sbjct: 4109 PLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSLKFEWFINGVELQ 4168 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 + +D V TL I V PEDAG + C A NAAG A S+T + V+ + G + Sbjct: 4169 MGSRLRTTHDFGFV-TLDITAVVPEDAGVYMCRAYNAAGEAVSSTAMKVKTKSNIDGQPL 4227 Query: 612 TVXXXXXXXXXXXXAD-----ILEGIP---PTFSKKPKA-QYVDEGSDILLECRLVAIPE 662 + ++ P P F+ ++ + EG +LLE ++ + Sbjct: 4228 IPESWEAIRLKEAAMNRVPEMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRAD 4287 Query: 663 PD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA- 719 P+ I W G + I S L I ++ YT A N+ GEA Sbjct: 4288 PNLRIEWFKNGISLTTGSR----IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAV 4343 Query: 720 ---------------------SLPIVLKIKTGEKEPPQVIEP----------LKSMIVRQ 748 SLP + +++ ++ P+ EP L ++ ++ Sbjct: 4344 STSSLKIEDRHWLQAESLHPDSLPRIGELEAPKEGRPEAPEPTYETPVFITHLNNIECKE 4403 Query: 749 GESVILSAQV--VGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYT 804 ++V V +P +I W N +P++A KS D + L ++ GVYT Sbjct: 4404 SDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKSIYDFGYCALDLTNSYAENSGVYT 4463 Query: 805 LKAENSEGIAETSAVI 820 KA NS+G A TS + Sbjct: 4464 CKATNSKGSATTSGTL 4479 Score = 64.5 bits (150), Expect = 3e-08 Identities = 83/337 (24%), Positives = 140/337 (41%), Gaps = 35/337 (10%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +EQ +AP FV++ +G + G P+P+ITW Q ++ S + + D Sbjct: 2190 KEQVVAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITW--QKDGVQISSTAERFVGID 2247 Query: 564 NVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 AT L I V DAG + C A+N AG ++ L VE P E Sbjct: 2248 GGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQRRL-------- 2299 Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 +P PT +P A+ + L++I D GE + N S Sbjct: 2300 --------NLPRPTKVIEPGARATSVFKFGFIALDLLSIMGHD-----SGEYMCRVTNAS 2346 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEP 740 ES SV++ ++++ + ++ +N+ E + I + PQ I P Sbjct: 2347 GVAES--RAILSVVQRPSIEQSSQNPNSLQYINQLEDYSRYQRTESIDEQLNQAPQFIRP 2404 Query: 741 LKSM-IVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKP 794 L+ + +G++V AQV V +P + W K+ P+ A + + S+ IL Sbjct: 2405 LRDLGEFEEGKNVHFEAQVTPVNDPSMRVEWYKDGLPITASSRITAIFNFGYVSLNILH- 2463 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + +D G YT++A N G A + + I V ++ A+ Sbjct: 2464 LRAEDAGTYTVRAVNRIGEAISQSSIRVHSRSQVTAD 2500 Score = 64.1 bits (149), Expect = 4e-08 Identities = 57/200 (28%), Positives = 85/200 (42%), Gaps = 24/200 (12%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRK-- 1073 P F +K+Q V E + A EVE E V W R+ P +N D + K Sbjct: 6030 PVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVKWYRES---FPIQNSPDLQIHTFSGKSI 6086 Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE---------LPPEIITRLQNQKVNK 1120 L IR V D +SC+ + C+A + V E PP +T +Q+ V Sbjct: 6087 LIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEERRRAGKGGIQPPSFVTTIQSTTVAT 6146 Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178 G A F+ ++T L V W K+G +IQ S ++ + L I + +D+G Y C Sbjct: 6147 GQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKMLEEDSVHTLLIIEPFAEDSGRYECV 6206 Query: 1179 ---EVGNSKCTAILTVEEPS 1195 G ++C V+ PS Sbjct: 6207 AVNAAGEARCDGDCIVQSPS 6226 Score = 63.3 bits (147), Expect = 7e-08 Identities = 60/238 (25%), Positives = 97/238 (40%), Gaps = 20/238 (8%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 AP F L T +G+ V EC+++ G P +I WF +K F+ Y+ D VA Sbjct: 2926 APQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYVA 2985 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASST--------TELIVEAPLSDHGSEMTVXXXXX 618 L + + D+G +TC A+N G A ++ +LI+E ++ Sbjct: 2986 -LDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQKIQYLEDST 3044 Query: 619 XXXXXXXADILEGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIV 675 D + I P F PK+ EG EC++ + +P+ + W G I Sbjct: 3045 RHRRSEFVDEVVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPIT 3104 Query: 676 PDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 +H + V L I ++ G YT AVN G + L+ ++GE+ Sbjct: 3105 VGHRFR-----PIHDFGYVALDIVHLIAEDSGVYTCRAVNLIGSDETQVELQCRSGEQ 3157 Score = 63.3 bits (147), Expect = 7e-08 Identities = 61/241 (25%), Positives = 95/241 (39%), Gaps = 21/241 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYD 561 E AP+F L+ + FEC++ P ++ W+ +K F + Sbjct: 3188 ESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFTETNN 3247 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL-----SDHGSEMTVXXX 616 VA L I PEDAGT+TC A NA G A ++ +V S H + + Sbjct: 3248 FGFVA-LDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIYLESQHETALPRLQH 3306 Query: 617 XXXXXXXXXADILEGI---PPTFSKKPKAQYVDEGSDILLECRLVAIPEP--DIAWLFKG 671 + + P F+ + V E + E RL+ + +P + WL G Sbjct: 3307 LEDGSKRQRISVQDEFVSQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNG 3366 Query: 672 EEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIK 728 + I + MH + V L + V GTYT AVN G+A S ++++ K Sbjct: 3367 QPIEASNRTTT-----MHDFGYVALNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSK 3421 Query: 729 T 729 T Sbjct: 3422 T 3422 Score = 62.9 bits (146), Expect = 9e-08 Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 18/234 (7%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 S AP+F +R + V FE ++ G P+ + W R I+ S +D Sbjct: 3324 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 3383 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGSEMTVXXXXXX 619 VA L ++ V PED+GT+TC A N G A ++ LIV++ S H + M Sbjct: 3384 VA-LNMKYVNPEDSGTYTCRAVNELGQAVTSASLIVQSKTSIQLETQHEAAMHKIHQLED 3442 Query: 620 XXXXXXADILE---GIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEE 673 + E P F +K + EG ECR+ P+P+ + W G+ Sbjct: 3443 HSRYQRREEEEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKVEWFHNGKP 3502 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 + + + L I V G YT N GEA IVL + Sbjct: 3503 LSTGHRFRTTYDFGF----AALDILTVYAEDSGEYTCRVTNNLGEAINSIVLNV 3552 Score = 60.5 bits (140), Expect = 5e-07 Identities = 55/238 (23%), Positives = 92/238 (38%), Gaps = 21/238 (8%) Query: 505 EQSMAPIFVEKLRPKHT-PDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561 ++ P FV +++ + T + + +FECQ+ G P ++ WF + FQ YD Sbjct: 5585 DRKQPPRFVTQIKEQLTLTEMAVTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFQPIYD 5644 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAG--------FASSTTELIVEAPLSDHGSEM-- 611 VA + V+PED+G + C A N G S ++ ++ L H + Sbjct: 5645 FGYVA-MNFGWVYPEDSGEYVCRATNLYGKDETRAIIKVSGKPGIVYDSQLPAHMQSIDR 5703 Query: 612 --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669 + D P F K + Q V+EG R+ P P + WL Sbjct: 5704 IREMEASWQVVPDEVDPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLI 5763 Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 G +V + + H L + +++ G V+A N GE+ LK+ Sbjct: 5764 NGHTVVHGSRYKLTNDGMFH-----LDVPKTRQYDTGKVEVIARNSVGESIATTELKV 5816 Score = 60.5 bits (140), Expect = 5e-07 Identities = 85/423 (20%), Positives = 164/423 (38%), Gaps = 30/423 (7%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 + P VE L G FE ++ + WF+ I ++ Q+ D + Sbjct: 16527 LPPEIVEPLNDVAVTKGENAVFEVELSKGDA-LVKWFKNGKEIVFNERIQLAIDGKKQSL 16585 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT-VXXXXXXXXXXXXA 626 +++ PED G ++ G +S +L VE PL D + + Sbjct: 16586 RIVKAK-PEDVGEYSV----QVGEQTSKAKLTVEEPLVDFVIRLPDITLATKTTDAEFTV 16640 Query: 627 DILE-GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 + + + T+ KK K ++ ++ +E + + D + GE EN++ + + Sbjct: 16641 QLSQPDVEVTWCKKGKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTK 16700 Query: 686 SDMHMYCSVLKITN-------VKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQ 736 + IT+ VK+ + T+TV + K I ++ P Sbjct: 16701 LCVEELKLPPVITSDKDQTIKVKENDDVTFTVKYTGVPTPEACWTTRKVVIPKSKRTIPT 16760 Query: 737 VIEPLKSMIVRQG------ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790 + E + +++ + V LS G P P +TW KN + ++ + + T Sbjct: 16761 IDEQSAKLTIKKDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQVFESRSIRYENRVAKYT 16820 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 I K ++ E YT A N +G AETS + +++ E +++ ++ + Sbjct: 16821 IEK-TTIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVE-----DKYLTQKLRTGSIL 16874 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 + A V P P++TW++ ++++T + V E SG YK A+N Sbjct: 16875 TIPATVRGYPQPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTRE-QSGKYKVTATN 16933 Query: 911 SAG 913 +G Sbjct: 16934 ESG 16936 Score = 58.0 bits (134), Expect = 3e-06 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568 P+F + + G FE ++ G P+P +TW R+ A + SQ F+M Y++ +L Sbjct: 1812 PVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVSL 1871 Query: 569 VIREVFPEDAGTFTCVAKNAAGFA 592 +I ++ P D G +TC A+N G A Sbjct: 1872 LINQIGPGDEGEYTCTARNQYGEA 1895 Score = 57.2 bits (132), Expect = 5e-06 Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 32/334 (9%) Query: 504 EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQ--ITWFRQTAIIKPSQDFQMYY 560 E Q P++ + L+ + H + + E VE P I W+ ++ F+M Sbjct: 4522 ETQYPPPVWTKPLQAEFHLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMT- 4580 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTT------ELIVEAPLSDHGSEMTV 613 + T+ + EV+ D G +TC A N AG A +STT E I+E+ G+E Sbjct: 4581 SEFGFVTMDMIEVYARDQGIYTCKAYNKAGEAFTSTTIFCSSKENIIESTQHPKGAEGLE 4640 Query: 614 XXXXXXXXXXXXADILE----GIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPD--IA 666 E GIPP F+ + + EG E L+ + + I Sbjct: 4641 QIQDLEDSLRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIE 4700 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W + G+ + + ++ + +V L++ K GTYT A N+ G A + L Sbjct: 4701 WFYNGKVLEASHRVRT-----IYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNL 4755 Query: 726 K-IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---AL 778 + + + P+ I+PL+ + Q + V +P + W N K ++ + Sbjct: 4756 ECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRI 4815 Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 T SD + + + + D G Y +A N G Sbjct: 4816 KTVSDFG-YVVLDISYLQDHDSGEYVCRAWNKYG 4848 Score = 56.4 bits (130), Expect = 8e-06 Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 24/253 (9%) Query: 481 TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVE--GYP 537 T+ LQK L E + K E T +EQ P F E+++ P+G + F+C+VE G P Sbjct: 5286 TESLQK-LEETMHKRE--ELVTEDEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDP 5342 Query: 538 RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 +I WF ++ D +A L + ++ D+G +TC A N G A+++ + Sbjct: 5343 TMRIEWFYNGHVMATGSRVHQLNDFGFIA-LDVDYIYARDSGEYTCRATNKWGTATTSAK 5401 Query: 598 --------LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYVDE 647 ++ E+ L + G ++E + PP F+ + + VDE Sbjct: 5402 VTCKGKHNIVYESQLPE-GMTSEKLKELERGRIPEAPKVVEEVFGPPKFTTQITSVTVDE 5460 Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + EC++ +P + W G+ + P + + M L I V Sbjct: 5461 AEAVRFECQVEPKTDPSLRVEWYRNGKPL-PSGH---RYRNIFDMGFVSLDILYVYGEDS 5516 Query: 706 GTYTVVAVNREGE 718 G Y A+N GE Sbjct: 5517 GEYVCRAINNYGE 5529 Score = 55.6 bits (128), Expect = 1e-05 Identities = 83/378 (21%), Positives = 146/378 (38%), Gaps = 40/378 (10%) Query: 370 ELPKEDVPEQYTI-TPRKSSAQKIDE---IVDEVTIKKRLNP---FEIFYTPVEVRCGDT 422 E+ + P+Q + T S K+ E ++ E ++ R +P E F + + G Sbjct: 4247 EMFVDSTPQQAPVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSR 4306 Query: 423 VFAVYSYVAETDEAINL-VEGERLYILDTSNQDWWYVQKHLT--EEKGWVPAQYLMDENN 479 + + + + T L + +Y +NQ V E++ W+ A+ L ++ Sbjct: 4307 IRSTFDFGLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDRHWLQAESLHPDSL 4366 Query: 480 YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY--P 537 +L + P +PT E P+F+ L + V+FEC VE P Sbjct: 4367 PRI---GELEAPKEGRPEAPEPTYE----TPVFITHLNNIECKESDNVRFECNVEPARDP 4419 Query: 538 RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--- 594 I WF ++ + F+ YD A L + + E++G +TC A N+ G A++ Sbjct: 4420 TMSIEWFYNGQPLQAAAKFKSIYDFGYCA-LDLTNSYAENSGVYTCKATNSKGSATTSGT 4478 Query: 595 -------TTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 T L + P + G E T + PP ++K +A++ Sbjct: 4479 LKCTGGKTMFLDTQHPQGEAGLEAVQETEEELANRYTSKTTKPETQYPPPVWTKPLQAEF 4538 Query: 645 -VDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 + E I LE + +P+ I W F G+ + + E + + V Sbjct: 4539 HLSEAQPIHLEANVEPKEDPNLFIEWYFNGKMLNHGSRFKMTSEFGF----VTMDMIEVY 4594 Query: 702 KFQEGTYTVVAVNREGEA 719 +G YT A N+ GEA Sbjct: 4595 ARDQGIYTCKAYNKAGEA 4612 Score = 55.6 bits (128), Expect = 1e-05 Identities = 58/274 (21%), Positives = 106/274 (38%), Gaps = 23/274 (8%) Query: 1464 ASETTE--YYKVIKETKIQSPT--VEKPLKNITTEP-----NEDIELTCIFGGVPQPKVT 1514 A+ETTE + I+E +Q P + P+ +P NE + F G P P V Sbjct: 6003 ATETTEVEHKGTIQERVVQGPVKPAKAPVFTKKIQPCRVFENEQAKFEVEFEGEPNPTVK 6062 Query: 1515 WYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 WYR+ ++ + T+ + + C+A N G + S + ++++ Sbjct: 6063 WYRESFPIQNSPDLQIHTFSGKSILIIRQVFVEDSAVFSCVAENRGGTAKCSANLVVEER 6122 Query: 1571 P------VITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 + S Q V L A + G P +V W KNG K++ ++ + Sbjct: 6123 RRAGKGGIQPPSFVTTIQSTTVATGQLARFDAKVTGTRPLDVYWLKNGMKIQPSIKFKML 6182 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 ++ + I E S +Y A N AG + + + PSKPE P Sbjct: 6183 EEDSVHTLLIIEPFAEDSGRYECVAVNAAGEARCDGDC-IVQSPSKPEKPTTPGSEKAPH 6241 Query: 1683 VTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIK 1715 + + K +++G + + ++ RW++ Sbjct: 6242 IVEQLKSQTVEEGSKVIFRCRVDGKPTPTARWMR 6275 Score = 54.4 bits (125), Expect = 3e-05 Identities = 63/246 (25%), Positives = 103/246 (41%), Gaps = 21/246 (8%) Query: 490 EKIDKLPVFE---KPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGY--PRPQITW 543 EKI +L + KP EE+ PIF+ L +H +G EC+VE P +I W Sbjct: 3702 EKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPINDPNLKIEW 3761 Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--- 600 F + ++ +D VA L I V+ ED GT+ C A N G A +T + V Sbjct: 3762 FCNGKQLPTGHRYRTTHDFGYVA-LDILYVYGEDTGTYICKATNQLGEAVNTCNVRVLNR 3820 Query: 601 EAPLSD--HGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK-AQYVDEGSDILLEC 655 + + D H + ++ + PP F+ + + + + EG E Sbjct: 3821 RSMILDTQHPDALEKIQKLESKVPNARTEVGDAPISPPHFTAELRGSTEIYEGQTAHFEA 3880 Query: 656 RLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 ++ + +P+ I + G+ + + + Y S L IT+ G Y+V AV Sbjct: 3881 QVAPVHDPNLRIEFYHNGKPLPSASRFHITFDFG---YVS-LDITHAVAEDAGEYSVRAV 3936 Query: 714 NREGEA 719 N G+A Sbjct: 3937 NALGQA 3942 Score = 53.6 bits (123), Expect = 6e-05 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+FV KL P+ +G +F +V G+PRP++ W + +++ +D + L Sbjct: 5728 PVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKL--TNDGMFHLD 5785 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + + D G +A+N+ G + +TTEL V A D+ Sbjct: 5786 VPKTRQYDTGKVEVIARNSVGESIATTELKVVARSDDY 5823 Score = 52.4 bits (120), Expect = 1e-04 Identities = 83/398 (20%), Positives = 148/398 (37%), Gaps = 46/398 (11%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 TE PLF ++ +E VT P P++ W+++ I + FD Sbjct: 218 TELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDK 277 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-----DVEKV--TFVKHLQKSY 938 LVI + DS + C ASN G A +++ +V+ V ++ LQ Sbjct: 278 GICRLVIEETFA-ADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGK 336 Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 T EG + C + + +W+ N K I I D V Sbjct: 337 AT-EGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 395 Query: 997 IKCIVKD----QETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047 C + + S L+V+ +P F L + + LE + +V Sbjct: 396 YTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEV 455 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY-------------SC----- 1089 W +G+ +P+ +KY++ G + L I +D G Y SC Sbjct: 456 YWLHNGKPFQPRDSKYEY---GRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVK 511 Query: 1090 -ILRDESCTAEVT--VVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSE 1145 L +E+ +E+ + + P + L++ + +G + + + + + V W+ + Sbjct: 512 GRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERP 571 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++ S +QL G + L I + +DAG Y NS Sbjct: 572 VKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINS 609 Score = 51.2 bits (117), Expect = 3e-04 Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 15/193 (7%) Query: 1091 LRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK-GDA--LVRWFKDGSEI 1146 LR + E + +PP T N + +G A FE L GD ++ WF +G + Sbjct: 4649 LRKDGSKPEQPDLGIPPRFTTEFVNIADIGEGELAHFEANLIPVGDQSMVIEWFYNGKVL 4708 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT-----VEEP---SINF 1198 + S+ ++ L++ ++D G Y+C N TA ++ V++P F Sbjct: 4709 EASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVDKPRGQKPRF 4768 Query: 1199 TLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 T + + A+ + + D L V WY ++ + + +SD L I Sbjct: 4769 TSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDI 4828 Query: 1256 RKCTEDDQCEYTC 1268 + D EY C Sbjct: 4829 SYLQDHDSGEYVC 4841 Score = 50.0 bits (114), Expect = 7e-04 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 GD ++ + G P P V W+K+G ++ + +Y T + + I+E + S++++ Sbjct: 239 GDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCR 298 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE--GPVIMREISRESVT 1684 ASN GT TL V + ++ + P I+R + T Sbjct: 299 ASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKAT 338 Score = 50.0 bits (114), Expect = 7e-04 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 8/175 (4%) Query: 746 VRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDE 800 + +GE A + VG+ I W N K ++A + T T ++ +L K ++D Sbjct: 4677 IGEGELAHFEANLIPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVALEVLGTK-IEDT 4735 Query: 801 GVYTLKAENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G YT +A N G AE S + V++P + I + + + + + Sbjct: 4736 GTYTCRATNKHGTAEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVND 4795 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P + WY N +++ S I D + L I+ + DSG+Y C A N G+ Sbjct: 4796 PDLKVEWYHNGKLMRHSNRIKTVSDFGYVVLDISYLQDH-DSGEYVCRAWNKYGE 4849 Score = 48.8 bits (111), Expect = 0.002 Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 3/110 (2%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQ 881 E E E P+FI I KE ++ V R+P SI W+ N + + + Sbjct: 4381 EAPEPTYETPVFITHLNNIECKESDNVRFECNVEPARDPTMSIEWFYNGQPLQAAAKFKS 4440 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 +D L +TN +E +SG Y C A+NS G ++ + K F+ Sbjct: 4441 IYDFGYCALDLTNSYAE-NSGVYTCKATNSKGSATTSGTLKCTGGKTMFL 4489 Score = 48.4 bits (110), Expect = 0.002 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 7/179 (3%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536 +P PL + D+ + I+ G P P++ ++G +L T + NR Sbjct: 976 APRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIE 1035 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAV 1595 Y A N G+ ++ + +++ + ++ Q K G++ + Sbjct: 1036 LKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVE 1095 Query: 1596 IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + G+P P V W K+ L++ E+ + + + + I++ + + S KY + A+N G Sbjct: 1096 VTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGG 1154 Score = 48.4 bits (110), Expect = 0.002 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 3/111 (2%) Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 ST L V+ FPP + K+G +T+ V+ P+P W+ + K +K + Sbjct: 1060 STADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGIS 1119 Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + S L I+K + TD+G Y +R N G A + IL+ PSP Sbjct: 1120 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILE-PSP 1169 Score = 48.0 bits (109), Expect = 0.003 Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 10/176 (5%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D E+ E + + + +V W +G ++ + L Sbjct: 2097 PAFVKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLM 2156 Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127 I N + D G C+ R+++ A++ V+E + P+ + R V +G T Sbjct: 2157 ITNVTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVAPQFVQRFSTMTVREGEPITMS 2216 Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + + W KDG +I + + IDG L+I +DAG Y C N Sbjct: 2217 ANAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQN 2272 Score = 48.0 bits (109), Expect = 0.003 Identities = 55/228 (24%), Positives = 98/228 (42%), Gaps = 11/228 (4%) Query: 201 IDNEVPEKINVPDDKETSQTP------TSFNKRSKLTPIKIERKEM-EVSTPQHAETVDG 253 I E+P+ + P + + P +SF + KLTP+KIE+ E + + + V+ Sbjct: 11502 IHQEIPKTVLQPYQRTEMELPQRARRDSSFKQPVKLTPMKIEKVEFKKPKMVEISSVVEF 11561 Query: 254 PQFXXXXX-XXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGI 312 PQ + + +LKS I+++ + P +++ + + ++ G Sbjct: 11562 PQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIRFV-PYAPYCFPYVVTELETNREVGE 11620 Query: 313 LSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372 LSRN+ EA +V K K EK ELE+ + S K E++ K + Sbjct: 11621 LSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLGAYESDHSDKSNKELLHPKYKRGKKE 11680 Query: 373 KEDVP-EQYTITPRKSSAQKIDEIVDEVTIKK-RLNPFEIFYTPVEVR 418 K + P E + K + +E +EV +K +L+ EI + VR Sbjct: 11681 KIETPDESRKLKFGKGKVPQNEEASEEVNLKPVKLDIAEIEDAEMPVR 11728 Score = 47.2 bits (107), Expect = 0.005 Identities = 62/270 (22%), Positives = 100/270 (37%), Gaps = 23/270 (8%) Query: 499 EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQV--EGYPRPQITWFRQTAIIKPSQD 555 ++P + P+F + L+ + T FE ++ G P ++ W+R II+ S Sbjct: 3981 QEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSR 4040 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615 +D V+ L I + ED G + C A N G A +T + V +S+ +M Sbjct: 4041 ITKQHDFGFVS-LDISHIRKEDEGVYMCRAVNPLGEAVTTASMRV---VSEASIQMDTQH 4096 Query: 616 XXXXXXXXXXADILEGIPP----TFSKKPKAQYVD------EGSDILLECRLVAIPEPDI 665 L P F K Q + EG+ E R+V + +P + Sbjct: 4097 PDSISRIHQLEKPLAPRPTEPERLFEKPIFTQLLTGPSELWEGTHAHFEARVVPVGDPSL 4156 Query: 666 --AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723 W G E+ + + + L IT V G Y A N GEA Sbjct: 4157 KFEWFINGVEL----QMGSRLRTTHDFGFVTLDITAVVPEDAGVYMCRAYNAAGEAVSST 4212 Query: 724 VLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 +K+KT Q + P +R E+ + Sbjct: 4213 AMKVKTKSNIDGQPLIPESWEAIRLKEAAM 4242 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 5/104 (4%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNNEIISPSETITQNFD 884 EE PP F + +TV E ++ +V PS + WYRN + + FD Sbjct: 5441 EEVFGPPKFTTQITSVTVDEAEAVRFECQVEPKTDPSLRVEWYRNGKPLPSGHRYRNIFD 5500 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + L I V E DSG+Y C A N+ G+ R T+ +K+ Sbjct: 5501 MGFVSLDILYVYGE-DSGEYVCRAINNYGEDR--TRATVSCKKL 5541 Score = 46.8 bits (106), Expect = 0.007 Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 5/105 (4%) Query: 815 ETSAVITVEEP-TEENAEPPLFINRFQEIT-VKEKGTIKLVARV--TRNPVPSITWYRNN 870 E++A +EP T + P+F Q I + E T AR+ +P + WYRN Sbjct: 3973 ESTAPHQRQEPETPGTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNE 4032 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 +II S IT+ D + L I+++ E D G Y C A N G++ Sbjct: 4033 KIIEDSSRITKQHDFGFVSLDISHIRKE-DEGVYMCRAVNPLGEA 4076 Score = 46.4 bits (105), Expect = 0.009 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 3/103 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + + A+ +G P PE+ KNG +L D I+ K I +K++ + +Y + Sbjct: 991 GADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVT 1050 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIE 1686 ASNT G S+ L V P G + ++S+ E +T+E Sbjct: 1051 ASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME 1093 Score = 46.4 bits (105), Expect = 0.009 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 22/165 (13%) Query: 1599 IPPPEVIWYKNGNKLEND--KEYNITTKEKT----SVIRIKELKRSHSSKYTIEASNTAG 1652 +P P+++W NG ++ + K I T+ SV+ I ++K+S Y + A+N G Sbjct: 16083 VPEPDIVWTFNGEDIDEEEIKNVRIVTESDMHMYCSVVHISKVKKSQEGTYEVIATNREG 16142 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 + + +TLKV + + E P I+ + R V + +G + I + P Sbjct: 16143 EARLPITLKV--RTTDKEAPQILEPL-RNMV-------IREGESVVLSTQIVGNPPPKVT 16192 Query: 1713 W------IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 W +K A D+D+ T + ++ + + V A NP+G E Sbjct: 16193 WYKDGKPVKNAKSDKDLHTLTLITPQKSEKGEYTVKAVNPLGSVE 16237 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 + PT + +AP F L K G+ V E +G+P P+I + + ++ Sbjct: 966 DSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRI 1025 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + N T+ +++V DAG + A N G ++ST +L+V+ Sbjct: 1026 -SNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVK 1067 Score = 45.2 bits (102), Expect = 0.020 Identities = 37/157 (23%), Positives = 67/157 (42%), Gaps = 13/157 (8%) Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 + + ++ + W +G++++ G + L + T + D G Y+C ++ T Sbjct: 4690 IPVGDQSMVIEWFYNGKVLEASHRVRTIYAFGTVA-LEVLGTKIEDTGTYTCRATNKHGT 4748 Query: 1098 AEVTV----VELP----PEIITRLQN-QKVNKGNKATFE---IELTKGDALVRWFKDGSE 1145 AE++ V+ P P + +Q + + G A FE I + D V W+ +G Sbjct: 4749 AEISCNLECVDKPRGQKPRFTSHIQPLEGLKDGQSAHFECTLIPVNDPDLKVEWYHNGKL 4808 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 ++ SN I+ D L I D+GEY C N Sbjct: 4809 MRHSNRIKTVSDFGYVVLDISYLQDHDSGEYVCRAWN 4845 Score = 44.8 bits (101), Expect = 0.026 Identities = 53/228 (23%), Positives = 86/228 (37%), Gaps = 17/228 (7%) Query: 507 SMAPIFVEKLR-PKHTPDGSTVQFECQVEGYPRPQ----ITWFRQTAIIKPSQDFQMYYD 561 + AP F+ L+ +G FE +VE P+ I W+ I + Q YYD Sbjct: 2669 TQAPRFLGPLKGTTKILEGQRAHFEARVE--PQSDLGLVIEWYHNGRSITAANRIQTYYD 2726 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 VA L I +V EDAG + VA+N +S T + + + Sbjct: 2727 FGYVA-LDISQVRAEDAGVYLVVARNKLARSSIDTSSMHRGL---YEKTQNLENKPFVEP 2782 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD--IAWLFKGEEIVPDEN 679 +I + P + + + +G +I LECRL + +P + W G + Sbjct: 2783 QYDIEEISKSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSR 2842 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 + + ++K T G YTV A N G A +++ Sbjct: 2843 FRTYYDFGF-VALDIIKATAA---DSGEYTVRATNHLGTAHTSACVRV 2886 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 4/99 (4%) Query: 827 EENAEPPLFINRFQE-ITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNF 883 +E PP F ++ + V E G I RV +P I W+ N +++ + Q Sbjct: 5306 DEQPNPPKFTEEIKDNLDVPEGGPIHFDCRVEPVGDPTMRIEWFYNGHVMATGSRVHQLN 5365 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 D I L + + + DSG+Y C A+N G ++ A+VT Sbjct: 5366 DFGFIALDVDYIYAR-DSGEYTCRATNKWGTATTSAKVT 5403 Score = 44.0 bits (99), Expect = 0.046 Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 17/212 (8%) Query: 44 LRKLQIEELESSKPQHPEEMTVPQFXXXXXXXXXXXXXQEPAVVK----LPKFQLKSRIK 99 L ++IE++E KP+ E +V +F QE K +LKS I+ Sbjct: 11537 LTPMKIEKVEFKKPKMVEISSVVEFPQMLKLKAPKQRPQEEKKKKNEASFKNKKLKSWIR 11596 Query: 100 FIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKSDLF 159 F+ + P +VT L + ++ GELSRNV EA E+ LE++DL Sbjct: 11597 FV-PYAPYCFPYVVTELETNREVGELSRNVDEAEEVLKLRPKKFKHSKPEKAELEEADLG 11655 Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219 + D S D S + PK ++ I E K VP ++E S+ Sbjct: 11656 AYESDHS--DKS-------NKELLHPKYKRGKKEKIETPDESRKLKFGKGKVPQNEEASE 11706 Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETV 251 K KL +IE EM V T Q E V Sbjct: 11707 EVNL--KPVKLDIAEIEDAEMPVRT-QEEEVV 11735 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 1/103 (0%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATL 568 P+F +L+ + + G + E +V G P P +TW + +K + N L Sbjct: 1073 PVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL 1132 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 +I + D+G + A NA G A S + + P + E+ Sbjct: 1133 IIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEV 1175 Score = 42.7 bits (96), Expect = 0.11 Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 2/119 (1%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F + K +G + L E RL P+P + W KG ++ + ++ ++ Sbjct: 1811 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSY-NEATGDV 1869 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S+L I + EG YT A N+ GEA + ++ + Q I+ L+ I G S Sbjct: 1870 SLL-INQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPIQNLEKNIYSNGYS 1927 Score = 42.7 bits (96), Expect = 0.11 Identities = 21/78 (26%), Positives = 35/78 (44%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 IS + K G + + TA + P P + W+ NG +L ++Y I+ + +R+K Sbjct: 1982 ISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRVKN 2041 Query: 1635 LKRSHSSKYTIEASNTAG 1652 YT+ A N G Sbjct: 2042 ATARDGGHYTLLAENLQG 2059 Score = 42.3 bits (95), Expect = 0.14 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 6/120 (5%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETIT 880 EE E + P+F + + +KE R+ +P + WY NN + T Sbjct: 3184 EEIDESTKQAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHNNLPLKSGSRFT 3243 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + + + L I + E D+G Y C A N+ G++ A + +K + L+ +ET Sbjct: 3244 ETNNFGFVALDIMSTLPE-DAGTYTCRAYNAVGEAITSAVAVVHTKKSIY---LESQHET 3299 Score = 42.3 bits (95), Expect = 0.14 Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 14/160 (8%) Query: 1461 ISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWY 1516 I +T+ + + E + + P +PL+N + L T I P KV WY Sbjct: 3571 IQHLEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWY 3630 Query: 1517 RDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +G+ ++T K TY+ Y C A N GE T+C V + Sbjct: 3631 CNGRPIQTGHRFKTTYDFGFVALDILYAHAEDTGTYMCKAKNAIGEAVTTCAVNVTANKT 3690 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 + + D ++ K+ L T PPP+ + + G K Sbjct: 3691 LDLDTLDAQRLEKI--RQLETYA----PPPKPVVEEKGQK 3724 Score = 42.3 bits (95), Expect = 0.14 Identities = 59/249 (23%), Positives = 103/249 (41%), Gaps = 22/249 (8%) Query: 164 DESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK-ETSQTPT 222 +ES D P ++ EA E + SE+P K E++ E EK DDK ET++ Sbjct: 13436 EESIIDEPIPEDYVVTEAAEE----KPSEEPTFKVEELETEAVEKEVTDDDKGETTKQSV 13491 Query: 223 SFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQL 282 + K KL K E E+ V T +T D P++ E P+ + Sbjct: 13492 TKRKIKKLVGPKEEIIEI-VET----KTGDTPEYEVIVTTEEVQEKSKEA-----PEEKK 13541 Query: 283 KSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL- 341 ++ P + ++ Y+ + + I +++ K+ V K ++K + Sbjct: 13542 AKTVRKAKKIPKDDLQ---DYIQKLIEQDIPKTELEKYEKIDLDEPVKMKRKPIKKVKQS 13598 Query: 342 -EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVT 400 EQP E+ +E K E +I + + + PK V + I P K + + +V E T Sbjct: 13599 EEQPKEETEEPIEDKPVE-KISEYSEVDSDEPKLTVAVKEFI-PEKPEEKPFEIVVLEET 13656 Query: 401 IKKRLNPFE 409 ++ + P E Sbjct: 13657 VESKREPDE 13665 Score = 41.5 bits (93), Expect = 0.25 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIE 889 PP+F F+ + G R+ NP P +TW R + S+ +++ ++ Sbjct: 1811 PPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEATGDVS 1870 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKS 915 L+I + D G+Y C A N G++ Sbjct: 1871 LLINQIGPG-DEGEYTCTARNQYGEA 1895 Score = 41.1 bits (92), Expect = 0.33 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 8/115 (6%) Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFG--GVPQPKVTWYRDGKKLKTA---KATYE- 1530 T +Q+P + L NI T ++ L C G P ++ W+ +GK +KT + YE Sbjct: 2922 TIMQAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEF 2981 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQK 1583 + Y C A N GE TSC V I K ++ NE QK Sbjct: 2982 DYVALDLLGCYAIDSGVYTCQARNQLGEAVTSCSVRIIAKNDLILETQNESGLQK 3036 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 12/129 (9%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGD 785 G+ PP + K+ QG + + ++ GNP+P +TW + P+ K + ++ Sbjct: 1807 GDISPPVFEQIFKNARFAQGGNALFEGRLRGNPKPFVTWTRKGAPLLESQKFRMSYNEAT 1866 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------EPTEENAEPPLFINR 838 ++ DEG YT A N G A S I E +P +N E ++ N Sbjct: 1867 GDVSLLINQIGPGDEGEYTCTARNQYGEAICSVYIQPEGAPMPALQPI-QNLEKNIYSNG 1925 Query: 839 FQEITVKEK 847 + +++E+ Sbjct: 1926 YSYTSIEEE 1934 Score = 40.7 bits (91), Expect = 0.43 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYNITTKE 1625 QQ PV T + + H+ G L+ A +E P + W+KNG L T Sbjct: 4255 QQAPVFTTHLQSYDKLHE-GQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDF 4313 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + I L+ S+ YT +A+N G + +LK+ D+ Sbjct: 4314 GLVTLSINGLRADDSAIYTCKATNQVGEAVSTSSLKIEDR 4353 Score = 40.3 bits (90), Expect = 0.57 Identities = 64/298 (21%), Positives = 114/298 (38%), Gaps = 39/298 (13%) Query: 1107 PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P+I + ++ K+ +G+ A F + + + WF +G + S +++ L++ Sbjct: 1980 PQISQKPRSSKLIEGSDAVFTARVGSNPKPRLTWFHNGQRLVASQKYEISYSSGVATLRV 2039 Query: 1166 YDCDLDDAGEYSCEVGNSK-C---TAILTVE-------EPS-INFTLRLPEF--ILVPAN 1211 + D G Y+ N + C +A+L VE EP ++ E L PA Sbjct: 2040 KNATARDGGHYTLLAENLQGCVVSSAVLAVEPAAETAYEPKPVDVMAEQLEAGKALPPAF 2099 Query: 1212 TDAYLTVEIPDETL-------------DVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRK 1257 A+ EI + + +V W + V +D L+++ +L+I Sbjct: 2100 VKAFGDREITEGRMTRFDCRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITN 2159 Query: 1258 CTEDDQCEYTC--------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 T D C V ++A+ K +VV P+ V ++ G +T+ Sbjct: 2160 VTRLDAGAVQCLARNKAGEVAIEAQLNVLEKEQVVA--PQFVQRFSTMTVREGEPITMSA 2217 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + PQP W + I ID + L I +V DAG Y+ +N G Sbjct: 2218 NAIGTPQPRITWQKDGVQISSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAG 2275 Score = 40.3 bits (90), Expect = 0.57 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 732 KEPPQVIEPLKS-MIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGD 785 K P + PL + G+++ L ++ +G+P + W N +PV T D Sbjct: 2791 KSKPVFVTPLSDPKPIHDGKNIHLECRLEPMGDPTMRVEWFHNGRPVTVGSRFRTYYDFG 2850 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 ++ I+K D G YT++A N G A TSA + V + T+ Sbjct: 2851 FVALDIIKATAA-DSGEYTVRATNHLGTAHTSACVRVIDHTD 2891 Score = 40.3 bits (90), Expect = 0.57 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 7/124 (5%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP--KVTWYRD 1518 + D S T ++ + TK Q+P LKN+ + N+ C V P +V WY + Sbjct: 3174 LEDRSRYTRREEIDESTK-QAPVFTTSLKNVEIKENQRAHFECRLIPVSDPSMRVEWYHN 3232 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 LK+ E Y C A+N GE TS V + K I Sbjct: 3233 NLPLKSGSRFTETNNFGFVALDIMSTLPEDAGTYTCRAYNAVGEAITSAVAVVHTKKSIY 3292 Query: 1575 ISNE 1578 + ++ Sbjct: 3293 LESQ 3296 Score = 40.3 bits (90), Expect = 0.57 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDGEN 887 ++ P+F +++ V E + AR+ +P ++ W RN + I S T D Sbjct: 3324 SQAPVFTMPVRDVRVAENQAVHFEARLIPVGDPKLTVEWLRNGQPIEASNRTTTMHDFGY 3383 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + L + V+ E DSG Y C A N G++ A + + Sbjct: 3384 VALNMKYVNPE-DSGTYTCRAVNELGQAVTSASLIV 3418 Score = 40.3 bits (90), Expect = 0.57 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 7/167 (4%) Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 I+ + DF D++ L+ + E W + GE + + RG + ++ Sbjct: 4815 IKTVSDFGYVVLDISYLQDHDSGEYVCRAWNKYGEDFT--RTTLNCGGRGGVFYDSLQPD 4872 Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTK---GDA 1135 S+ E C ++ T+ V E PP+ IT++ + K+ +G A FE LT D Sbjct: 4873 SLQRIRELECPQGQQADTSAPLVAE-PPKFITQIVDVTKLVEGQSAHFEARLTPITDPDL 4931 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 +V W+ +G ++ + + D L I C +++G Y N Sbjct: 4932 VVEWYFNGKKLPHGHRFRTFHDFGIVILDILYCYEENSGVYEARARN 4978 Score = 40.3 bits (90), Expect = 0.57 Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 10/108 (9%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 +L + +KP E + +KLR GS + V GYP+P +TW ++T K + Sbjct: 16848 RLKLQQKPVLEVEDK--YLTQKLRT-----GSILTIPATVRGYPQPTVTWHKETIEQKTT 16900 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG--FASSTTELI 599 + + + +T +++V E +G + A N +G + T ++I Sbjct: 16901 KSVTI-ETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVI 16947 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 +P + P+F+++ + TV+E + RVT +P P + W N + Sbjct: 5719 DPDAKPRTKPVFVSKLEPQTVEEGDPARFCVRVTGHPRPRVMWLINGHTVVHGSRYKLTN 5778 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 DG L + + D+G + +A NS G+S Sbjct: 5779 DG-MFHLDVPKT-RQYDTGKVEVIARNSVGES 5808 Score = 39.5 bits (88), Expect = 0.99 Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQV--VGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787 E PQ PL++ V +G V L A + V +P + W N +P++ T D Sbjct: 3592 ERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFV 3651 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ IL +D G Y KA+N+ G A T+ + V Sbjct: 3652 ALDILYAH-AEDTGTYMCKAKNAIGEAVTTCAVNV 3685 Score = 39.1 bits (87), Expect = 1.3 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 1106 PPEIITRLQNQ-KVNKGNKATFEIELTK-GDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161 PP+ T +QNQ + + A FE L GD+ +R W KDG ++ S+ I + Sbjct: 2537 PPQFKTPIQNQLDLREHAHAHFEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYV 2596 Query: 1162 KLKIYDCDLDDAGEYSCEVGNS 1183 L I + DAG Y+C N+ Sbjct: 2597 ALTIKQLTIYDAGTYTCRAYNA 2618 Score = 39.1 bits (87), Expect = 1.3 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 3/117 (2%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNN 870 + +TS + + +AE P F + V E + L A + +P + WY N Sbjct: 3574 LEDTSRFQRKTDEEQFHAERPQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNG 3633 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 I +D + L I +E D+G Y C A N+ G++ V + K Sbjct: 3634 RPIQTGHRFKTTYDFGFVALDILYAHAE-DTGTYMCKAKNAIGEAVTTCAVNVTANK 3689 Score = 39.1 bits (87), Expect = 1.3 Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 6/130 (4%) Query: 815 ETSAVITVEEPTEEN-AEPPLFINRFQEI-TVKEKGTIKLVARVTR--NPVPSITWYRNN 870 E S V T EE TEE + P+F + I ++E AR+T +P + WY N Sbjct: 5018 EYSMVRTREETTEETKGKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYWNG 5077 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VT 929 + D + L I+ V E DSG+Y C A N G++ A + I ++ + Sbjct: 5078 RPLKAGSRFRTFCDFGFVILEISPVYPE-DSGEYSCRAINEYGEAVTTATMKIQGKRSII 5136 Query: 930 FVKHLQKSYE 939 L K E Sbjct: 5137 MESQLPKGME 5146 Score = 38.7 bits (86), Expect = 1.7 Identities = 81/389 (20%), Positives = 135/389 (34%), Gaps = 37/389 (9%) Query: 1272 DAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 +A+ LKV + P+I++ R I+ G V L P P W + K +K Sbjct: 16143 EARLPITLKVRTTDKEAPQILEPLRNMVIREGESVVLSTQIVGNPPPKVTWYKDGKPVKN 16202 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 K D +LT+ + ++ G Y ++ N G + N+TI + +P + Sbjct: 16203 AKS-----DKDLHTLTLITPQKSEKGEYTVKAVNPLGSVETTANLTIEEPAGGNAEPPLF 16257 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 N+ P+ + V + +W+ IQ + + Sbjct: 16258 VERFEEQNV----PQK--GEIRLPAKVSGNPVPEVQWLFNNTPLFPSERIQQVYDGENIE 16311 Query: 1451 FRAYAVN-EVDISD--------ASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIE 1500 N E D D +T+ +VI E + T K L K IT E + + Sbjct: 16312 LIIKDANPETDSGDYKCIASNPIGKTSHGARVIVE--VDEVTFTKKLKKTITIEEVQSLT 16369 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK--TAKATYEN--RXXXXXXXXXXXXXXXYKCIAFNDH 1556 L C V K W+ +GK+L + E+ Y C Sbjct: 16370 LECETSHVVTTK--WFFNGKELSGMDHRVVVEDGKTHKLVIRNTNLRDSGTYTCKVKKQE 16427 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-EN 1615 + S V +Q+KP ED + K + + V EV WYK+G K+ Sbjct: 16428 TQ---STVEVLQRKPDFIKVLEDYEVTEK---DTAILDVELTTEATEVTWYKDGEKITPE 16481 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 +K K + I+++ +YT Sbjct: 16482 NKNVEFIKDGKARRLVIRDVTIHDEGQYT 16510 Score = 38.3 bits (85), Expect = 2.3 Identities = 35/193 (18%), Positives = 75/193 (38%), Gaps = 10/193 (5%) Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 C G P P+V W +G++++ + +C+A N G Sbjct: 2118 CRVTGNPYPEVFWLINGRQVRDDASHKILVNESGSHSLMITNVTRLDAGAVQCLARNKAG 2177 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 EV + + +K + ++ + +++ + G+ ++A G P P + W K+G ++ Sbjct: 2178 EVAIEAQLNVLEKEQV-VAPQFVQRFSTMTVREGEPITMSANAIGTPQPRITWQKDGVQI 2236 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 + E + + + I + + + Y A N AG+++ L V +P Sbjct: 2237 SSTAERFVGIDGGATCLEIPRVTANDAGWYQCTAQNIAGSTANRARLYVEVPREQPNYEQ 2296 Query: 1674 IMREISRESVTIE 1686 + R + IE Sbjct: 2297 RRLNLPRPTKVIE 2309 Score = 38.3 bits (85), Expect = 2.3 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787 + PQ L ++ +G +V L Q VG+P I W N KPVK + D Sbjct: 2925 QAPQFTRGLHNIETIEGTNVHLECRLQPVGDPSMRIEWFVNGKPVKTGHRFRPAYEFDYV 2984 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ +L + D GVYT +A N G A TS + + Sbjct: 2985 ALDLLGCYAI-DSGVYTCQARNQLGEAVTSCSVRI 3018 Score = 38.3 bits (85), Expect = 2.3 Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 11/128 (8%) Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD---ALVRWFK 1141 EYS + E T E P L+N + + +G A FE +T D V W+ Sbjct: 5018 EYSMVRTREETTEETK--GKAPVFTVPLENIENLREGENAHFEARITPADDPKLKVEWYW 5075 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI 1196 +G ++ + + D L+I +D+GEYSC E G + TA + ++ + SI Sbjct: 5076 NGRPLKAGSRFRTFCDFGFVILEISPVYPEDSGEYSCRAINEYGEAVTTATMKIQGKRSI 5135 Query: 1197 NFTLRLPE 1204 +LP+ Sbjct: 5136 IMESQLPK 5143 Score = 38.3 bits (85), Expect = 2.3 Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 27/257 (10%) Query: 159 FDSQEDESKPDVSQPPQN--IIEEAKSE---PKLIEESEQP-IAKTSEIDNEVPEKINVP 212 F +++ E KP V + P+ I++ K + P+++EE E + K EV E+ + Sbjct: 15329 FATKDSEKKPTVEELPEEQVTIQKKKKKAPVPEVVEEPEAEFLVKPKTPVQEVTEEAKIT 15388 Query: 213 DDKE-TSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271 K+ + + + +T E++ + E + E Sbjct: 15389 KSKKPVKEEEAAAELKVTITEEIPTEPEVQEIIEEIEEIEEEKPAEYVIEVKESQPEAVE 15448 Query: 272 TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331 V LPK + K+ I E + I+ +K S ++E AK+ K+ P Sbjct: 15449 DKEVSLPKKKPKAPIV-------EEPEAEITLKPKVK-----SEEVQEEAKIVKKK--PK 15494 Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYT----ITPRKS 387 K+ +V + E + E++V E E+I+E + +++ PKE PE + +K Sbjct: 15495 KIDEVAVAD-ELTVKVEEEVVPEPIVEEEVIEEFE-IKKKPKEPEPEDIVDAAIVKLKKP 15552 Query: 388 SAQKIDEIVDEVTIKKR 404 DE+V EVT+K + Sbjct: 15553 EPVDADEVVAEVTLKPK 15569 Score = 38.3 bits (85), Expect = 2.3 Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 7/98 (7%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 PT +EQS A + ++K V C G P P++TW + + + S+ + Sbjct: 16759 PTIDEQS-AKLTIKKDVVSELD--KEVTLSCVFGGIPEPKVTWKKNGQVFE-SRSIRY-- 16812 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598 ++ VA I + E T+TCVA N G A ++ L Sbjct: 16813 -ENRVAKYTIEKTTIETEATYTCVATNEKGSAETSCRL 16849 Score = 37.9 bits (84), Expect = 3.0 Identities = 36/169 (21%), Positives = 60/169 (35%), Gaps = 11/169 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------LDAKSTTKLK 1280 V W+K I+ + D L+I + D ++C D +T ++ Sbjct: 256 VEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVR 315 Query: 1281 ---VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 EV PP+I+ + + + GS P P +W N K I S Sbjct: 316 ENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVIS 375 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPP 1384 ++ A+L ++V D +Y N G H + V L+ P Sbjct: 376 YNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELP 424 Score = 37.9 bits (84), Expect = 3.0 Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 18/195 (9%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 PP I L+ + + A E + + + L +WF I+ SN +++ K L Sbjct: 8387 PPRFIQPLEPKYFGEHEVAIIEA-IVESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTL 8445 Query: 1164 KIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINF-TLRLPEFILVPANT---- 1212 I + G ++C N S T L +E + F + R E ++ P Sbjct: 8446 LIENFQSKFVGPFTCRAENVGGSVTSTATVNLIPQEEAEEFESPRFVEELVQPVEVMDGE 8505 Query: 1213 DAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVL 1270 LT ++ + T V WY I + ++ T+ D++ L I + +++ +Y CV Sbjct: 8506 ALLLTCQVTGKPTPKVEWYHNAEKITENKETTISQDLQGVCQLQITEVFPENEGQYECVA 8565 Query: 1271 LD--AKSTTKLKVEV 1283 + KS +K V++ Sbjct: 8566 TNKIGKSVSKTNVKI 8580 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/86 (24%), Positives = 39/86 (45%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + +G+DV++ Y FP P + N + + HT+ S ++ +K+V DAG Y Sbjct: 988 VDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRY 1047 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384 + N G + ++ + PP Sbjct: 1048 AVTASNTVGQSTSTADLVVKKTIFPP 1073 Score = 37.5 bits (83), Expect = 4.0 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALV 1137 +H ++S R E E TV P + + + +G A +E + + V Sbjct: 3437 IHQLEDHSRYQRREE--EEYTVTTAPVFVTKLIGPSNLVEGQSAHYECRIEPYPDPNLKV 3494 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 WF +G + + + T D L I +D+GEY+C V N+ AI ++ Sbjct: 3495 EWFHNGKPLSTGHRFRTTYDFGFAALDILTVYAEDSGEYTCRVTNNLGEAINSI 3548 Score = 37.5 bits (83), Expect = 4.0 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 5/124 (4%) Query: 804 TLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEIT-VKEKGTIKLVARVT--RN 859 TL A+ E I + +P EE + P+F+ + +KE L RV + Sbjct: 3695 TLDAQRLEKIRQLETYAPPPKPVVEEKGQKPIFLTPLSNLEHLKEGEHAHLECRVEPIND 3754 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P I W+ N + + D + L I V E D+G Y C A+N G++ + Sbjct: 3755 PNLKIEWFCNGKQLPTGHRYRTTHDFGYVALDILYVYGE-DTGTYICKATNQLGEAVNTC 3813 Query: 920 RVTI 923 V + Sbjct: 3814 NVRV 3817 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Query: 1107 PEIITRLQNQKVNKGNKATFE---IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 P+ L+N KVN+G E I + V W+ +G IQ + + T D L Sbjct: 3594 PQFGRPLRNAKVNEGAPVHLEATLIPVNDPTMKVEWYCNGRPIQTGHRFKTTYDFGFVAL 3653 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILT 1190 I +D G Y C+ N+ A+ T Sbjct: 3654 DILYAHAEDTGTYMCKAKNAIGEAVTT 3680 Score = 37.1 bits (82), Expect = 5.3 Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 9/121 (7%) Query: 730 GEKEPPQVIEPLKSMI-VRQGESVILSAQV--VGNPRPTITWCKNNKPVK---ALPTKSD 783 G ++ P +PL+++ + + ++ A++ VG+P + W +N K ++ + + D Sbjct: 3987 GTRQRPVFTQPLQNIDRINEHQTAHFEARLIPVGDPNLKVEWYRNEKIIEDSSRITKQHD 4046 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEPTEENAEPPLFINRFQE 841 S+ I +K +DEGVY +A N G A T+A + V E + + + P I+R + Sbjct: 4047 FGFVSLDISHIRK-EDEGVYMCRAVNPLGEAVTTASMRVVSEASIQMDTQHPDSISRIHQ 4105 Query: 842 I 842 + Sbjct: 4106 L 4106 Score = 37.1 bits (82), Expect = 5.3 Identities = 64/274 (23%), Positives = 108/274 (39%), Gaps = 20/274 (7%) Query: 162 QEDESKPDVSQPPQNIIEEAKS---EPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETS 218 +ED KP V PQ ++ E K +P+ + E + +A T + V + P +E Sbjct: 7116 EEDLIKP-VQPEPQPVLWERKKKKPQPQDVIEEKLDVAPTKTYEKAVDVLPDEPKVEEKP 7174 Query: 219 QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLP 278 + P + + K P K E E EV H + VD K P Sbjct: 7175 E-PVLWQRGKKKIP-KSEPTE-EV----HPDEVDAQIETVVKEDEMIVEEKRRIKKTKRP 7227 Query: 279 KFQLKSRIKYITSWPPESIKP-----LISYMGSIKQNGILSRNIKEAAKVK-KQVFVPPK 332 K + + P E I P + I++ R +K+ K K Q + Sbjct: 7228 KSTKEVTEELFEEQPEEEISPEEEVPQKEVIEEIEEIVEEKRRLKKTKKPKLTQQVTEEE 7287 Query: 333 LPDVEKT-ELEQPLFSYEDIVESKKDENEIIQEKQTLE-ELPKEDVPEQYTITPRKSSAQ 390 P E E E+ + E+IVE KK ++ + K E +L +E++P + T+ +++ Sbjct: 7288 TPHEEIIKESEEVVQEQEEIVEEKKKVKKVKKPKTVAEKQLKEEEIPTEETVEEEETAED 7347 Query: 391 KIDEIVDEVTIKKRLNPF-EIFYTPVEVRCGDTV 423 + + + +KK P + T VE G+ V Sbjct: 7348 QQLVVEESKKVKKVKKPTGTVEKTDVEELPGEEV 7381 Score = 37.1 bits (82), Expect = 5.3 Identities = 75/392 (19%), Positives = 156/392 (39%), Gaps = 33/392 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 P KL+ + ++ +LE ++ + +I+ KY+ + KL I Sbjct: 8090 PRITEKLRPRQCVPEEPTVLECKVEGVPFPEIKWYFNDILLFASEKYEITVMEQVAKLKI 8149 Query: 1077 RNTSVHDEGEYSCILRDES--CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT- 1131 + D G Y+C ++E+ T+ ++ + + +K + K T ++T Sbjct: 8150 AKVTPSDVGVYTCEAKNEAGVATSRTNIILGKFTKPLKIEFIEEKQPERLKVTVTCQVTG 8209 Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGNSKCTA-- 1187 K + V+W++ E+ S +Q+ D K L++ + ++A YS + N A Sbjct: 8210 KPNPEVKWYRGIEEVIPSETVQMFYDEKTGDVALEVINPTPNEAVVYSVQAQNQFGRAIG 8269 Query: 1188 ---ILTVEEPSINFTLRLP-----EFILVPANTDAYLTVEIPD-ETLDVTWYKK-KSVIE 1237 IL+ + L+ P ++VP + + +V W + + +IE Sbjct: 8270 NANILSRVDEVPREILKAPTVTPLSAVVVPTGGTLFFEAKYDGLPRPEVKWMRNGREIIE 8329 Query: 1238 DTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLDAKSTTKLKV------EVVEF 1286 + E T+I + T I RK T + + +AKS+ + V E ++ Sbjct: 8330 NEE--TIIETTETTTTIKVVNMTRKRTGKYEVWAKNKVGEAKSSGSVVVSDQKPDEQIKP 8387 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P I E +Y + + + ++ P + +W V+++ IK + + ++L Sbjct: 8388 PRFIQPLEPKYFGEHEVAIIEAI-VESEPLSSFQWFVHNEPIKSSNEVRIVSQANKSTLL 8446 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 I+ ++ G + R EN G V ++ Sbjct: 8447 IENFQSKFVGPFTCRAENVGGSVTSTATVNLI 8478 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%) Query: 529 FECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 FE ++E G ++ W + ++ S Y++ VA L I+++ DAGT+TC A Sbjct: 2558 FEARLEPVGDSTMRVEWLKDGQPLEASSRITTYHNFGYVA-LTIKQLTIYDAGTYTCRAY 2616 Query: 587 NAAGFASSTTELIV 600 NA G ++ +L V Sbjct: 2617 NAMGQDTTVAQLTV 2630 Score = 36.7 bits (81), Expect = 7.0 Identities = 41/185 (22%), Positives = 77/185 (41%), Gaps = 15/185 (8%) Query: 1102 VVELPPEIITRLQN-QKVNKGNKATFEIEL---TKGDALVRWFKDGSEIQFSNHIQLTID 1157 VV + P +T ++ +G A FE ++ T + V WFK+G I + + D Sbjct: 3055 VVNIRPRFLTHPKSLTNTREGGHAHFECKIEPVTDPNLKVEWFKNGRPITVGHRFRPIHD 3114 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 L I +D+G Y+C N ++ +E + R E I+ +A L Sbjct: 3115 FGYVALDIVHLIAEDSGVYTCRAVN-----LIGSDETQVELQCRSGEQIVTVTQNEAGL- 3168 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 E D + Y ++ I+++ K + + + I+ E+ + + C L+ S Sbjct: 3169 -EQIHYLEDRSRYTRREEIDESTKQAPVFTTSLKNVEIK---ENQRAHFECRLIPV-SDP 3223 Query: 1278 KLKVE 1282 ++VE Sbjct: 3224 SMRVE 3228 Score = 36.7 bits (81), Expect = 7.0 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%) Query: 1107 PEIITRLQN-QKVNKGNKATFEIELT-KGDALVR--WFKDGSEIQFSNHIQLTIDGKKQK 1162 P T LQ+ K+++G E ++ + D +R WFK+G + + I+ T D Sbjct: 4258 PVFTTHLQSYDKLHEGQHVLLEAQVEPRADPNLRIEWFKNGISLTTGSRIRSTFDFGLVT 4317 Query: 1163 LKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193 L I DD+ Y+C +VG + T+ L +E+ Sbjct: 4318 LSINGLRADDSAIYTCKATNQVGEAVSTSSLKIED 4352 Score = 36.3 bits (80), Expect = 9.2 Identities = 16/62 (25%), Positives = 28/62 (45%) Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 EW N K+++ + + +L + + D G Y R N G A++ N+ +D Sbjct: 4700 EWFYNGKVLEASHRVRTIYAFGTVALEVLGTKIEDTGTYTCRATNKHGTAEISCNLECVD 4759 Query: 1380 KP 1381 KP Sbjct: 4760 KP 4761 >UniRef50_Q7QJK9 Cluster: ENSANGP00000010739; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000010739 - Anopheles gambiae str. PEST Length = 1776 Score = 793 bits (1961), Expect = 0.0 Identities = 439/1161 (37%), Positives = 630/1161 (54%), Gaps = 28/1161 (2%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A+ EGI T A +TV+E N + PLF+ RF+E +V + GTIKL ARVT NPVP I W Sbjct: 627 ADILEGIPPT-AFLTVDESNVGNPQAPLFLERFEEQSVPQGGTIKLPARVTGNPVPEILW 685 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 RNN + PS+ + Q +DGENIEL+I N DSE DSG+YKC+ASN+ GK+SHGARVT++V+ Sbjct: 686 LRNNNTLLPSKRVKQAYDGENIELLINNADSEQDSGNYKCIASNTIGKASHGARVTVEVD 745 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 KVTF K L+K+ EE ++V LEC+TSHTVSTKW+HN KE+SGMDHR I+QEG+ Sbjct: 746 KVTFTKKLKKTITVEESRSVTLECETSHTVSTKWFHNGKELSGMDHRMIVQEGKVHKLNI 805 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D GV +C VKDQ+T L V E PEF+RKL+D E KEK+ A+LEVEI SETAD Sbjct: 806 KNPTINDTGVYRCTVKDQQTECSLTVIEAKPEFLRKLEDVETKEKEHAVLEVEITSETAD 865 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 V W ++G + KY+F K+G R L++RNTSVHDEGEY+C L D+ C+AEV+V+ELP Sbjct: 866 VTWYKEGRKLVDTTGKYEFAKKGKSRVLFVRNTSVHDEGEYTCALADQECSAEVSVIELP 925 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 PEII+ ++ V +G A FE+ELTKGDALVRW+++ E+ F+ H+QLTIDGK+Q LKI Sbjct: 926 PEIISAPRDVTVARGEDAIFELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQTLKIN 985 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 D GEY+C VG + A LTVE+P ++F RLPE L + DA VE+ E+ D Sbjct: 986 KTVDADGGEYTCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVEL-SESAD 1044 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 V WY+ I + K+ L+ D R LI++ EDD+ EYTC + +AK+++KLKVE+++ Sbjct: 1045 VVWYRNSKAITASSKYELVVDKCIRKLIVKNSVEDDENEYTCTVSNAKTSSKLKVEIIKV 1104 Query: 1287 PPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P I D R + I++ DVT V + A P+P EW VN ++I ++ ++ASL Sbjct: 1105 APTIFEDGARTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASL 1164 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 TIK+ DAG + L+L N CG A + I +P P P I SI + W P Sbjct: 1165 TIKRAAEVDAGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATLITDDSITLFWKAPS 1224 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + GNS I Y++EYQE + +W V +IT+T T++ L N+ Y FRA A+NEV AS Sbjct: 1225 DDGNSKITEYLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPAS 1284 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT- 1524 + YYK++ + ++PTV + LK++ + + L+CI GVP P V W+R+G+ LK Sbjct: 1285 PNSPYYKIMAPIQKEAPTVSEHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQD 1344 Query: 1525 -AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ- 1582 T Y A N G + + KP +++ Sbjct: 1345 HTIVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVREL 1404 Query: 1583 -KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 V EW + G+ + K + +N + I++L S Sbjct: 1405 SPEAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQY 1464 Query: 1642 KYTIEASNTAGTSS--VEVTLKV---YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + + A N G S T+K+ + PS P GP+ ++ S T+ W+P +GG Sbjct: 1465 HFRVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMTSSSFTLMWQPSESNGGS 1524 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 ++T+Y +E E W KVA ET I+ L N Y F++ A+N VG SE L++ Sbjct: 1525 KITEYVVEVKEAKKKVW-KVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQT 1583 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII--DYKVEIKQEGKKW 1813 ++ + +T P++ +++ G W Sbjct: 1584 VESIVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDW 1643 Query: 1814 KXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + + T FRI+A N +G S P S+ T PS P Sbjct: 1644 TKIKTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSE---------TVPSPPTG 1694 Query: 1872 FVVSESTSRSVTL-KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 + ++ + +W PES+GG+PI Y I + K W ++ V I+++ Sbjct: 1695 PLEVRYLGPNINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDL 1754 Query: 1931 KEKDEIIFRISAENTVGVSLP 1951 +E ++ + RI A N VG+S P Sbjct: 1755 QESEDYLIRIMARNEVGLSDP 1775 Score = 530 bits (1309), Expect = e-148 Identities = 356/1098 (32%), Positives = 555/1098 (50%), Gaps = 77/1098 (7%) Query: 993 DVGVIKCIVKDQETSTMLVVKETIP----EFIRKLQD-FEVKEKDVAILEVEINSETADV 1047 D G KCI + + T+ F +KL+ V+E LE E S T Sbjct: 719 DSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLKKTITVEESRSVTLECE-TSHTVST 777 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W +G+ + ++ ++ G + KL I+N +++D G Y C ++D+ +TV+E P Sbjct: 778 KWFHNGKELSGMDHRMIVQE-GKVHKLNIKNPTINDTGVYRCTVKDQQTECSLTVIEAKP 836 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIY 1166 E + +L++ + + A E+E+T A V W+K+G + + + + GK + L + Sbjct: 837 EFLRKLEDVETKEKEHAVLEVEITSETADVTWYKEGRKLVDTTGKYEFAKKGKSRVLFVR 896 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 + + D GEY+C + + +C+A ++V E P I + P + V DA +E+ Sbjct: 897 NTSVHDEGEYTCALADQECSAEVSVIELPPEI---ISAPRDVTVARGEDAIFELELTKGD 953 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-- 1282 V WY+ + + L D K++TL I K + D EYTCV+ + ++ +L VE Sbjct: 954 ALVRWYRNEEELSFNGHVQLTIDGKRQTLKINKTVDADGGEYTCVVGEQRAKARLTVEKP 1013 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 VV+F ++ + R +D V+ + W NSK I + +D Sbjct: 1014 VVDFVRRLPEVTLT---TRDNDAVFAVELSE--SADVVWYRNSKAITASSKYELVVDKCI 1068 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L +K D Y + N ++ V I+ P I E + + I D Sbjct: 1069 RKLIVKNSVEDDENEYTCTVSN--AKTSSKLKVEIIKVA-----PTIFEDGARTFTIRKD 1121 Query: 1403 EPENTG---NST----IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 E N+T + V + I + +++S +I+ + F Sbjct: 1122 EDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASLTIKRAAEVDAGEFTLKL 1181 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP---- 1511 NE + AS T +IK+ Q E P + T D +T +F P Sbjct: 1182 TNECGDASASFTL----IIKK---QPGAPEAPEATLIT----DDSIT-LFWKAPSDDGNS 1229 Query: 1512 KVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---- 1563 K+T Y ++ + K + T ++ A N+ G+ S Sbjct: 1230 KITEYLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPASPNSPY 1289 Query: 1564 --VVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 ++ QK T+S E +K H +G ++ ++ G+P P+V W++NG L+ D + Sbjct: 1290 YKIMAPIQKEAPTVS-EHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQD--HT 1346 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 I T ++S I I L R+H+ KYT+EA N AG+++VE+TLKV DKPSKPEGP+++RE+S Sbjct: 1347 IVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVRELSP 1406 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMF 1739 E+V IEWKPP DDGGLE++++ IEK + N N WIKVADV R++++YCIQKL ++ +Y F Sbjct: 1407 EAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQYHF 1466 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 RVIAQNPVG SE LES + I+ ++ PS + + S + W PSE NGGS I Sbjct: 1467 RVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMTSSSFTLMWQPSESNGGSKI 1526 Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 +Y VE+K+ KK WK I+ L++N Y F+I A+N++G+S P + + Sbjct: 1527 TEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQTVES 1586 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF-KTVKGKSWTKI 1915 I GK ++ + + V + + + + + P+ + +T G WTKI Sbjct: 1587 IVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDWTKI 1646 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 T+ + +C++N+KEK E++FRI AEN VG+S PT S+ TVPSPPT PLE+ Sbjct: 1647 KTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSE--------TVPSPPTGPLEV 1698 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 R +G NI + WG PE DGGAP+ GY IAIR+ KTMWMEVG+V + FNI+DL E+ Sbjct: 1699 RYLGPNINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDLQESE 1758 Query: 2036 TYMIRIYARNEIGLSEPL 2053 Y+IRI ARNE+GLS+PL Sbjct: 1759 DYLIRIMARNEVGLSDPL 1776 Score = 432 bits (1065), Expect = e-119 Identities = 430/1693 (25%), Positives = 735/1693 (43%), Gaps = 137/1693 (8%) Query: 147 DLERVTLEKSDLFDSQEDESKPDVSQP---PQNII-EEAKSEPKLIEESEQPIAKTSEID 202 ++E+ LE+ + + E + KP+ +P PQ I +E K++ LI E E+ Sbjct: 135 EIEKTQLEQYEKVEL-ESKPKPEKLKPVLVPQKIERKEQKAQKMLISEPEEQPQMVRLRK 193 Query: 203 NEVPEKINVPD---DKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXX 259 +VPE+ + + K + K +++ K+ V P+ T D P + Sbjct: 194 VKVPERKEIEEVVVPKVLLKMKPKKKVEEKPKEEELDSKKRSVEKPKFTPT-DIPDYETP 252 Query: 260 XXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKE 319 E V+ P+ + + P E ++ +G K+ ++ Sbjct: 253 LEPYVKPEPEPEEKPVQEPEKPKVPKEPKVPEVPEEPEHKIV--LGKGKKP---EPEPED 307 Query: 320 AAKVKKQVFVPPKLPDVEKTELE-QPLFSYEDIVESKKDENE----IIQEKQTLEELPKE 374 K +K V P P+ EK E++ +P E K+ E + + K ++L + Sbjct: 308 EFKFRKPV---PTKPEEEKEEIKLKPFTKPTPDTEPKEREADRDMALPVPKDITKKLLEM 364 Query: 375 DVPEQYTITPRKSSAQKID---EIVDEVTIKKRLNPFE-IFYTPVEVRCGDTVFAVYSYV 430 DVP+ K + E VDEVT+ KR + EV ++ + Sbjct: 365 DVPKTELEKYEKIDLDVVKPPKETVDEVTMVKRKPKVKPSVEEEEEVETKLSLPKKKPSI 424 Query: 431 AETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGW-VPAQYLMDENNYTQ------- 482 E +EA + R + +D V+ LT K VPA+ + E+ + Sbjct: 425 TEPEEAEATFKVARKPSVPQQAED---VEASLTITKEEEVPAEEEITEHVVVRKQRPRPK 481 Query: 483 --YLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540 + ++ L+E+ ++ +K +AP +EKL+P T DG TVQFEC+VEG+PRP Sbjct: 482 PAFRREVLDEEEVRIKKIKKVRQPRPPLAPKIIEKLQPITTQDGYTVQFECKVEGFPRPS 541 Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ITWFRQTA+IKPSQDFQ+YYDDDNVATL+IREVFPEDAGTFTCVAKN AGFASS TEL+V Sbjct: 542 ITWFRQTAVIKPSQDFQIYYDDDNVATLIIREVFPEDAGTFTCVAKNIAGFASSATELVV 601 Query: 601 EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT-----------------FSKKPKAQ 643 ++ SDHGS++ ADILEGIPPT F ++ + Q Sbjct: 602 DSYSSDHGSDVATLSRKSMSRESSLADILEGIPPTAFLTVDESNVGNPQAPLFLERFEEQ 661 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V +G I L R+ P P+I WL ++P + + A + + L I N Sbjct: 662 SVPQGGTIKLPARVTGNPVPEILWLRNNNTLLPSKRVKQAYDGEN----IELLINNADSE 717 Query: 704 QE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 Q+ G Y +A N G+AS + ++ + + ++ K++ V + SV L + + Sbjct: 718 QDSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLK--KTITVEESRSVTLECET--SH 773 Query: 763 RPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 + W N K + + + +G H + I P + D GVY ++ + T Sbjct: 774 TVSTKWFHNGKELSGMDHRMIVQEGKVHKLNIKNPT-INDTGVYRCTVKDQQ----TECS 828 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSET 878 +TV E E F+ + +++ KEK L +T + +TWY+ +++ + Sbjct: 829 LTVIEAKPE------FLRKLEDVETKEKEHAVLEVEIT-SETADVTWYKEGRKLVDTTGK 881 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 G++ L + N S D G+Y C ++ A V++ +E + + Sbjct: 882 YEFAKKGKSRVLFVRNT-SVHDEGEYTCALADQ----ECSAEVSV-IELPPEIISAPRDV 935 Query: 939 ETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 G+ I E + T +WY N++E+S H ++ +G+ D G Sbjct: 936 TVARGEDAIFELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQTLKINKTVDADGGEY 995 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV-AILEVEINSETADVVWERDGEII 1056 C+V +Q L V++ + +F+R+L + + +D A+ VE+ SE+ADVVW R+ + I Sbjct: 996 TCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVEL-SESADVVWYRNSKAI 1054 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITR-L 1113 +KY+ IRKL ++N+ DE EY+C + + +++ V ++++ P I Sbjct: 1055 TAS-SKYELVVDKCIRKLIVKNSVEDDENEYTCTVSNAKTSSKLKVEIIKVAPTIFEDGA 1113 Query: 1114 QNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 + + K TF ++ W + I S T+ + L I D Sbjct: 1114 RTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEETASLTIKRAAEVD 1173 Query: 1173 AGEYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANT-DAYLTVEIPDETLDVTW 1229 AGE++ ++ N +A T+ PE L+ ++ + D +T Sbjct: 1174 AGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATLITDDSITLFWKAPSDDGNSKITE 1233 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD------AKSTT---KLK 1280 Y + ++ +K+T ++ + + T + K T++ + + ++ A + K+ Sbjct: 1234 YLLEYQEKNQKKWTEVTSITETTTTVTKLTKNAEYTFRATAINEVGKGPASPNSPYYKIM 1293 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 + + P + ++ ++ + G VTL P P+ W N + +K+ HT ++ Sbjct: 1294 APIQKEAPTVSEHLKDVHVGLGQTVTLSCIVTGVPVPDVAWFRNGQPLKQ-DHTIVTV-G 1351 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINI 1399 +S+++ I ++ G Y + N G A VE+ + ++DKPS P P ++ E+ ++ I Sbjct: 1352 QSSTIVISSLDRAHTGKYTVEARNAAGSATVELTLKVIDKPSKPEGPIVVRELSPEAVVI 1411 Query: 1400 CWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAV 1456 W P + G I + +E + + WI V ++ + S IQ L ++ Y FR A Sbjct: 1412 EWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQRNIKSYCIQKLIDSTQYHFRVIAQ 1471 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ---PKV 1513 N V S+ E+ K+ + + SP P I T T ++ K+ Sbjct: 1472 NPVGCSEPLESAT-VKIQQTVEPPSP----PRGPIETSGMTSSSFTLMWQPSESNGGSKI 1526 Query: 1514 TWY----RDGKK--LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE-TSCVVG 1566 T Y ++ KK K A T + +K A N G E V Sbjct: 1527 TEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDFKITAKNKVGSSEPLQTVES 1586 Query: 1567 IQQKPVITISNED----IKQKHKVGDEWLVTAVIEGIPPP--EVIWYKNGNKLENDKEYN 1620 I I+ ED + + V+ + P P ++ W + +D Sbjct: 1587 IVAGKEISKYWEDQATCVHVFRANACQVTVSCCVTTCPCPVVKLEWQQPETNGGSDWTKI 1646 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 T + + +K + I A N G SS V+ V PS P GP+ +R + Sbjct: 1647 KTLESNCLSYCVDNMKEKTELLFRIFAENAVGLSSPTVSETV---PSPPTGPLEVRYLGP 1703 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 +EW P DGG + Y I W++V V D +++ I+ L E+ +Y+ R Sbjct: 1704 NINIVEWGIPESDGGAPIEGYTIAIRNAKKTMWMEVGRVAADCQSFNIKDLQESEDYLIR 1763 Query: 1741 VIAQNPVGFSEAL 1753 ++A+N VG S+ L Sbjct: 1764 IMARNEVGLSDPL 1776 Score = 231 bits (565), Expect = 2e-58 Identities = 225/978 (23%), Positives = 405/978 (41%), Gaps = 71/978 (7%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + R + Q V +G +T + W ++ + + S ++ DG+ +L I Sbjct: 652 PLFLERFEEQSVPQGGTIKLPARVTGNPVPEILWLRNNNTLLPSKRVKQAYDGENIELLI 711 Query: 1166 YDCDLD-DAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 + D + D+G Y C +G + A +TVE + FT +L + I V + L E Sbjct: 712 NNADSEQDSGNYKCIASNTIGKASHGARVTVEVDKVTFTKKLKKTITVEESRSVTLECET 771 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 T+ W+ + + ++ + K L I+ T +D Y C + D + T+ Sbjct: 772 -SHTVSTKWFHNGKELSGMDHRMIVQEGKVHKLNIKNPTINDTGVYRCTVKDQQ--TECS 828 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 + V+E P+ + + K L V+ + + K++ + + Sbjct: 829 LTVIEAKPEFLRKLEDVETKEKEHAVLEVEITSETADVTWYKEGRKLVDTTGKYEFAKKG 888 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 KS L ++ D G Y L + E++V L P P + + I Sbjct: 889 KSRVLFVRNTSVHDEGEYTCALADQ--ECSAEVSVIELP-PEIISAPRDVTVARGEDAIF 945 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 E E T ++ + +E+ + + K QT LK N + VD Sbjct: 946 --ELELTKGDALVRWYRNEEELSFNGHVQLTIDGKRQT----LKINKT----------VD 989 Query: 1461 ISDASETTEYYKVIKETKIQSP-TVEKPLKNIT------TEPNEDIELTCIFGGVPQPKV 1513 ++ EY V+ E + ++ TVEKP+ + T D + V Sbjct: 990 ----ADGGEYTCVVGEQRAKARLTVEKPVVDFVRRLPEVTLTTRDNDAVFAVELSESADV 1045 Query: 1514 TWYRDGKKLKTAKATYENRXXX-----XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 WYR+ K + TA + YE Y C N +TS + ++ Sbjct: 1046 VWYRNSKAI-TASSKYELVVDKCIRKLIVKNSVEDDENEYTCTVSN----AKTSSKLKVE 1100 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 V ED + + + VT ++ P PE W N + ++ T E+ Sbjct: 1101 IIKVAPTIFEDGARTFTIRKDEDVTFSVKFNATPKPEAEWRVNKRVIIPSAKFVSTVTEE 1160 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 T+ + IK + ++T++ +N G +S TL + +P PE P I+ +S+T+ Sbjct: 1161 TASLTIKRAAEVDAGEFTLKLTNECGDASASFTLIIKKQPGAPEAPEATL-ITDDSITLF 1219 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 WK P DDG ++T+Y +E E + +W +V + T + KL +N EY FR A N Sbjct: 1220 WKAPSDDGNSKITEYLLEYQEKNQKKWTEVTSITETTTT--VTKLTKNAEYTFRATAINE 1277 Query: 1747 VGFSEALESEP---IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 VG A + P I+ + P+ ++V ++ + G P+ D Sbjct: 1278 VGKGPASPNSPYYKIMAPIQKEAPTVSEHLKDVHVGLGQTVTLSCIVT----GVPVPDVA 1333 Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTY--QFRIYARNEIGTSLPYTSDDKITIGK 1861 + K + I S++ + ++ + ARN G++ ++T+ K Sbjct: 1334 WFRNGQPLKQDHTIVTVGQSSTIVISSLDRAHTGKYTVEARNAAGSATV-----ELTL-K 1387 Query: 1862 TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVTVG 1919 + PS+P VV E + +V ++W P +GG I+ + IE K+ W K+ V Sbjct: 1388 VIDKPSKPEGPIVVRELSPEAVVIEWKPPSDDGGLEISQFTIEKCDDANKNAWIKVADVQ 1447 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 ++ +CI+ + + + FR+ A+N VG S P ES +V++++ PSPP P+E + Sbjct: 1448 RNIKSYCIQKLIDSTQYHFRVIAQNPVGCSEPLESATVKIQQTVEPPSPPRGPIETSGMT 1507 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 S+ W E +GG+ + Y + +++ K +W G + I +L+ N Y Sbjct: 1508 SSSFTLMWQPSESNGGSKITEYVVEVKEAKKKVWKVAGTTSASETSLLIENLAMNKAYDF 1567 Query: 2040 RIYARNEIGLSEPLESDE 2057 +I A+N++G SEPL++ E Sbjct: 1568 KITAKNKVGSSEPLQTVE 1585 Score = 41.5 bits (93), Expect = 0.25 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 4/94 (4%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P P AP E ++ + + W P DG + + Y + ++ + W EV + T Sbjct: 1200 PGAPEAP-EATLITDDSITLFWKAPSDDGNSKITEYLLEYQEKNQKKWTEVTSITETTT- 1257 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 + L++N Y R A NE+G P + P+ Sbjct: 1258 -TVTKLTKNAEYTFRATAINEVG-KGPASPNSPY 1289 Score = 39.9 bits (89), Expect = 0.75 Identities = 57/262 (21%), Positives = 104/262 (39%), Gaps = 10/262 (3%) Query: 149 ERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPE- 207 E V E++ + D ++ + + P+ + ++ K +PK + SE+ ++ E+ + Sbjct: 80 ETVASEETTVLDDKKLKPTTEAQAEPKKVEKKVKKKPKKDKPSEEDEQLQRLLNLEIEKT 139 Query: 208 KINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXX 267 ++ + E P + L P KIERKE + +E + PQ Sbjct: 140 QLEQYEKVELESKPKPEKLKPVLVPQKIERKEQKAQKMLISEPEEQPQMVRLRKVKVPER 199 Query: 268 XXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQV 327 E V +PK LK + K P+ + L S S+++ +I + + + Sbjct: 200 KEIEE--VVVPKVLLKMKPKKKVEEKPKE-EELDSKKRSVEKPKFTPTDIPD-YETPLEP 255 Query: 328 FVPPKLPDVEK--TELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPR 385 +V P+ EK E E+P E V +E E K L + K + + R Sbjct: 256 YVKPEPEPEEKPVQEPEKPKVPKEPKVPEVPEEPE---HKIVLGKGKKPEPEPEDEFKFR 312 Query: 386 KSSAQKIDEIVDEVTIKKRLNP 407 K K +E +E+ +K P Sbjct: 313 KPVPTKPEEEKEEIKLKPFTKP 334 >UniRef50_UPI0000E48847 Cluster: PREDICTED: similar to titin isoform N2-A; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to titin isoform N2-A - Strongylocentrotus purpuratus Length = 10984 Score = 388 bits (956), Expect = e-106 Identities = 352/1352 (26%), Positives = 584/1352 (43%), Gaps = 95/1352 (7%) Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 I W K+ + P + K DG S++I + +D G YT+K I + + + Sbjct: 1025 IVWMKDGQKITPDEKFQVKRDGRRLSLSI-QDTSPEDSGQYTIK------IGDKTQTADL 1077 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 + E +P +N E TI L ++ VP WY+++ +I+ + Sbjct: 1078 KVQAAEFVKP---LNNTSAAEYDE--TIVLECELSNELVPC-QWYKDDVLITVGPKVEVI 1131 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 DG+ +LV+ +V E D+G+++CV + + T+DV+ +K L + E Sbjct: 1132 DDGKKRKLVLHDVRPE-DTGNFRCVVGDKESSA------TLDVKASEIMKPLAEVTAPEF 1184 Query: 943 GKTVILECQTSHT-VSTKWYHNKKEISGMD----HREIIQEGRXXXXXXXXXXXXDVGVI 997 +T +LEC+ SH W + + I+ + E++ +GR D Sbjct: 1185 AETAVLECEVSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEF 1244 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 C V D +T + VK +P + L+D + +LE E+++E A V W ++G+ I Sbjct: 1245 TCKVGDNQTVANVNVK--VPSITKPLEDTTTAFETTVVLECEVDNEKAPVKWMKNGKEIT 1302 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 K KY E +G R+L I T DEG+Y+C++ DES A + V P E ++ +Q+ + Sbjct: 1303 -KMPKYLMESKGKKRRLTIFETIPEDEGDYTCVVGDESTVAVLAVEPAPIEFLSEIQSVQ 1361 Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEY 1176 + A F E++ +A V W K+ EI+ + + + GKK+ LKI D+ D E+ Sbjct: 1362 AVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEF 1421 Query: 1177 SCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW-YKKK 1233 +C+ + +A LTV E P+I+ TL+ + + + + E ET DV W +K K Sbjct: 1422 TCKTKDKTSSASLTVTEHIPTISHTLK--DVKIEEGSNEVVFECETDVETADVAWLHKGK 1479 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY 1293 ++ED KF + ++ +LI++ + +D E+TC + ++ +L VEV EF + Sbjct: 1480 DIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAELIVEV-EF---LAPL 1535 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 +E G ++T V+ + + W+ + + IK + K D K L IKKV+ Sbjct: 1536 PKEQSAIPGDEITFEVELTKDTE-DVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKVDFD 1594 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STI 1412 D +Y N G + N+ + P P + I + E TG+ + + Sbjct: 1595 DDAVYSF----NAGDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAIEATVTGSPAAV 1650 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 + I++T+ ++ + SI+ L + + R +D T Sbjct: 1651 TTWSKGDTPIESTKRFKIEAGKGPKASIR-LTIDKTERSDLGTYTLTAANDLGTDTAIIF 1709 Query: 1473 VIKETKIQSPT----VEKPLKNIT---TEPNEDIELTCIFGGVPQPK-VTWYRDGKKLKT 1524 +I K Q PT E +++T T P +D GG P + V RD K+ Sbjct: 1710 IIVLDKPQPPTSLSITETTPESVTLVWTAPEDD-------GGSPVIEYVIEKRDMKRNTW 1762 Query: 1525 AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-- 1582 K + ++ A N+ G E +PV D+ Sbjct: 1763 TKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTT----SEPVTAKYQFDVPHAP 1818 Query: 1583 -KHKVGDEWLVTAVIEGIPPP-----EVIWYKNGNKLENDKEYNITTKEKTSVI--RIKE 1634 K + D + PP EV Y K + + TKE + + R+K+ Sbjct: 1819 SKPETSDVIQTEMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKD 1878 Query: 1635 LKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWK 1688 L S ++ + A N AGTS S K YD P P P +++ ++T+ W Sbjct: 1879 LIEGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTC-ENVNKTTITVSWT 1937 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPV 1747 PP DDGG +T Y IE+ + RW+K + D+ E T+ + L + +Y FR+ A+N Sbjct: 1938 PPEDDGGSPVTGYVIERCDVSRGRWVK-CNRDKVTELTFTVSDLTDGGQYQFRISAENAA 1996 Query: 1748 GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 G + + S K D P + + ITW P E +GGSP+ + VE Sbjct: 1997 GVGQPSPTSATFTAKLPFDAPGAPGKPQVTEY-NITKMTITWTPPESDGGSPVTGFVVER 2055 Query: 1807 KQE-GKKWKXXX--XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 K++ +W + L+ + YQFR+ A N G D Sbjct: 2056 KEKTSSRWVRVTKETVTETTLTVTGLTEGSEYQFRVIAENLAGPGPASEPSDLQKAKLPF 2115 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 P+ P ++ + + L WT PES+GGSPIT Y IE K GK WTK + + Sbjct: 2116 DVPTAPGKPDITSADKTEMELTWTIPESDGGSPITGYTIEKKEKTGK-WTKAIKTVVTET 2174 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNI 1982 + + EK E FR++A N G +E ++ K VP PP+ P + + I Sbjct: 2175 TTTVTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVPGPPSKPTTENINKTTI 2234 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 +T W PE DGG+P+ GY + + + W++ K V L I DL E + Y R+ Sbjct: 2235 TIT-WTPPENDGGSPVTGYIVEKCEGARGRWVKCNKDLVTELTLTISDLHEGNDYQFRVS 2293 Query: 2043 ARNEIGLSEPLESDEPFKV-IPGEGSHADEEP 2073 A N G+ +P + K +P + A +P Sbjct: 2294 AENAAGVGQPGPPSDTVKAKLPFDAPGAPGKP 2325 Score = 338 bits (830), Expect = 1e-90 Identities = 369/1483 (24%), Positives = 595/1483 (40%), Gaps = 126/1483 (8%) Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 +LEC V+ P+ + WL G+ I P+E S E L I +V K +T Sbjct: 1189 VLECE-VSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEFTCK 1247 Query: 712 AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 + + A++ + + P + +PL+ +V+L + V N + + W KN Sbjct: 1248 VGDNQTVANVNV---------KVPSITKPLEDTTTAFETTVVLECE-VDNEKAPVKWMKN 1297 Query: 772 NKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 K + +P +S G +TI + +DEG YT G T AV+ VE Sbjct: 1298 GKEITKMPKYLMESKGKKRRLTIFETIP-EDEGDYTCVV----GDESTVAVLAVE----- 1347 Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGEN 887 P F++ Q + E ++ + + W +N E I P E G+ Sbjct: 1348 -PAPIEFLSEIQSVQAVEDEPAVFTCEISDDNA-EVIWLKNEEEIKPDDEKYEFVVSGKK 1405 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT-V 946 L I + D D+ ++ C + +S +T+ E + + H K + EEG V Sbjct: 1406 RGLKIKSTDVS-DTAEFTCKTKDKTSSAS----LTV-TEHIPTISHTLKDVKIEEGSNEV 1459 Query: 947 ILECQTS-HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 + EC+T T W H K+I + + +I ++GR D G C + Sbjct: 1460 VFECETDVETADVAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVH 1519 Query: 1005 ETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 ET L+V+ EF+ L ++ D EVE+ +T DV W +DG+ IKP N Sbjct: 1520 ETIAELIVE---VEFLAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDN-V 1575 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT--RLQNQKVNKG 1121 K G KL I+ D+ YS D+ C + V PP+I +L N V G Sbjct: 1576 KIVKDGKKHKLIIKKVDFDDDAVYSFNAGDQKCDCNLN-VSAPPKINVDPKLTNISVKAG 1634 Query: 1122 NKATFEIELTKGDALV-RWFKDGSEIQFSNHIQLTI-DGKKQ--KLKIYDCDLDDAGEYS 1177 K E +T A V W K + I+ + ++ G K +L I + D G Y+ Sbjct: 1635 TKIAIEATVTGSPAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYT 1694 Query: 1178 CEVGNSKCT-----AILTVEEP----SINFTLRLPEFILV----PANTDAYLTVEIPDET 1224 N T I+ +++P S++ T PE + + P + +E E Sbjct: 1695 LTAANDLGTDTAIIFIIVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEK 1754 Query: 1225 LDV---TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 D+ TW K + E T + + V+ + R ++ T K + Sbjct: 1755 RDMKRNTWTKVDTTSELTCRVPKL--VEGNEYLFRVSATNELGTSEPFTTSEPVTAKYQF 1812 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 +V P K E I+ +T D+ + +I+ K K + K + ++ Sbjct: 1813 DVPHAPSK---PETSDVIQTEMTLTWTPPDFNGGSEVTG-YIIERKEADKTRWVKITKET 1868 Query: 1341 KSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVT------ILDKPSPPGKPNILEI 1392 + LT + + + Y+ R+ N G + T D P PP +P + Sbjct: 1869 VT-ELTFRVKDLIEGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTCENV 1927 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYR 1450 + ++I + W PE+ G S + YV+E ++ W+ +T+ ++ +L Y+ Sbjct: 1928 NKTTITVSWTPPEDDGGSPVTGYVIERCDVSRGRWVKCNRDKVTELTFTVSDLTDGGQYQ 1987 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN-EDIELTCI----F 1505 FR A N + S T+ + K+ P K TE N + +T Sbjct: 1988 FRISAENAAGVGQPSPTSATF----TAKLPFDAPGAPGKPQVTEYNITKMTITWTPPESD 2043 Query: 1506 GGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEV 1559 GG P VT + +K KT+ + T E Y + IA N G Sbjct: 2044 GGSP---VTGFVVERKEKTSSRWVRVTKETVTETTLTVTGLTEGSEYQFRVIAENLAGPG 2100 Query: 1560 ETSCVVGIQQKPV-----ITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKNGNK 1612 S +Q+ + DI K E W + G P K Sbjct: 2101 PASEPSDLQKAKLPFDVPTAPGKPDITSADKTEMELTWTIPESDGGSPITGYTIEKKEKT 2160 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT------SSVEVTLKVYDKP 1666 + K E T+ + +L ++ + A N AGT S ++ YD P Sbjct: 2161 GKWTKAIKTVVTETTTT--VTKLIEKKEYQFRVAAINLAGTGPFSEPSDNKMAKAPYDVP 2218 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-T 1725 P P I++ ++TI W PP +DGG +T Y +EK E RW+K + D E T Sbjct: 2219 GPPSKPT-TENINKTTITITWTPPENDGGSPVTGYIVEKCEGARGRWVK-CNKDLVTELT 2276 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 I L+E +Y FRV A+N G + S+ + K D P + + Sbjct: 2277 LTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKAKLPFDAPG-APGKPQVTEYNITKM 2335 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYA 1841 ITW P E +GGSP+ + VE K+ +W + L+ + YQFR+ A Sbjct: 2336 TITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIVTGLTEGSEYQFRVIA 2395 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N G D PS P V+ + + L W P+S+GGSPIT YI Sbjct: 2396 ENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSADKTQMELTWAVPDSDGGSPITGYI 2455 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 I+ K GK WT+ + + I+++ EK E FR++A N G +E ++ K Sbjct: 2456 IQKKENTGK-WTQSLKTTTTETTATIKSLIEKKEYEFRVAAVNLAGTGPFSEPSDYQIAK 2514 Query: 1962 HA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 VP PP P + + +++ +T W PE DGG+P+ GY + RD + W +V + Sbjct: 2515 APYDVPGPPGKPTILEVDSTSMTIT-WTPPETDGGSPVTGYVVEKRDRVSSRWTKVKETS 2573 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + + + I DL E + Y R+ A N+ G+ +P E + + P Sbjct: 2574 IEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKP 2616 Score = 308 bits (755), Expect = 2e-81 Identities = 220/802 (27%), Positives = 358/802 (44%), Gaps = 45/802 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ G+ L V ++A P+P +W + ++ K + +TIK D G + Sbjct: 7887 VRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSF 7946 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVV 1417 KL + N G + + V +LD+P P P + +I S+ + + W EP +TG S I +Y++ Sbjct: 7947 KLDVSNTAGSDAITIRVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYII 8006 Query: 1418 EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 E +E D T W + T + +L+ +SY FR +AVN++ S+ ET E K+ K+ Sbjct: 8007 ERREEDRTSWTRLTTRALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKK 8066 Query: 1477 TKI-QSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 + ++P+ KPL T + +E GG P ++ Y KK +T+ + Sbjct: 8067 YDVPEAPS--KPLVTNVTSDSVTLEWHSPKSDGGAP---ISGYIIEKK-ETSSNYWSKVT 8120 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED--IKQKH------- 1584 + + E G P I ED + K Sbjct: 8121 TVSSGVTSHRIPRLMRGEEYEFRVSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEP 8180 Query: 1585 ---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 KVG+ + + GIP P V W +G L+ I T + S I +K +++++ Sbjct: 8181 IMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGG 8240 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 +YTI NTAG S++V ++V+D+P P GP+ M +S +VT+ W PP DDGG + Y Sbjct: 8241 RYTINLKNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTY 8300 Query: 1702 AIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760 ++K +W K + D ++ TY + L EN +Y FRV+A+N G S+ LE + I Sbjct: 8301 VVQKRGEIETKW-KHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITP 8359 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW--KXXX 1817 + +VP I +SV + W P +GG+P+ Y VE++Q +W Sbjct: 8360 QGQYNVPDPPSAPKVTNII-GDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLT 8418 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVS 1875 R +L T Y+FR+ A N GT P + + + P + F Sbjct: 8419 PTPDMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFEKV 8478 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEK 1933 + T + P +P ++ TV+ + I + G ++ E Sbjct: 8479 ITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSG 8538 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 D + I A N G T + +V PSPP PL + +GSN V SW P D Sbjct: 8539 DYV---IRASNKAGEDTVTVTVNV-----VDSPSPPQGPLALVKLGSNEVTLSWSRPRDD 8590 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 GG+P+ GY + R+ W V +T F + L+E+ Y R+ A N +G+SEPL Sbjct: 8591 GGSPITGYVLEKREGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPL 8649 Query: 2054 ESDEPFKVIPGEGSHADEEPGE 2075 ES+ ++IP ++PG+ Sbjct: 8650 ESE---RIIPKGDYDVPDQPGK 8668 Score = 284 bits (696), Expect = 2e-74 Identities = 220/825 (26%), Positives = 365/825 (44%), Gaps = 55/825 (6%) Query: 660 IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719 + + DI W+ G++I PDE V + L I + G YT+ + G+ Sbjct: 1020 VKDEDIVWMKDGQKITPDEKFQVKRDGRRLS----LSIQDTSPEDSGQYTI----KIGDK 1071 Query: 720 SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779 + LK++ E ++PL + + + I+ + N W K++ + P Sbjct: 1072 TQTADLKVQAAE-----FVKPLNNTSAAEYDETIVLECELSNELVPCQWYKDDVLITVGP 1126 Query: 780 TKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836 DG + +L + +D G + G E+SA + V+ E +P Sbjct: 1127 KVEVIDDGKKRKL-VLHDVRPEDTGNFRCVV----GDKESSATLDVK--ASEIMKP---- 1175 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGENIELVI 892 E+T E ++ +P TW ++ + I+P E ++ + DG L+I Sbjct: 1176 --LAEVTAPEFAETAVLECEVSHPKAEATWLKDGQPITPEELTSKKYEVVSDGRKRRLII 1233 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 +V + D+ ++ C G + A V + V +T K L+ + E TV+LEC+ Sbjct: 1234 HDVVKD-DNAEFTC----KVGDNQTVANVNVKVPSIT--KPLEDTTTAFE-TTVVLECEV 1285 Query: 953 SHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV 1011 + + KW N KEI+ M + +G+ D G C+V D+ T +L Sbjct: 1286 DNEKAPVKWMKNGKEITKMPKYLMESKGKKRRLTIFETIPEDEGDYTCVVGDESTVAVLA 1345 Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071 V+ EF+ ++Q + E + A+ EI+ + A+V+W ++ E IKP KY+F G Sbjct: 1346 VEPAPIEFLSEIQSVQAVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKK 1405 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG-NKATFEIEL 1130 R L I++T V D E++C +D++ +A +TV E P I L++ K+ +G N+ FE E Sbjct: 1406 RGLKIKSTDVSDTAEFTCKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECET 1465 Query: 1131 TKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189 A V W G +I + ++ + G++ L + D ++DAGE++C +G + A L Sbjct: 1466 DVETADVAWLHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAEL 1525 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 VE + F LP+ + VE+ +T DV W K I+ + ++ D K Sbjct: 1526 IVE---VEFLAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGK 1582 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI-VDYE-REYRIKRGSDVTL 1307 K LII+K DD Y+ D K L V PPKI VD + +K G+ + + Sbjct: 1583 KHKLIIKKVDFDDDAVYSFNAGDQKCDCNLNVSA---PPKINVDPKLTNISVKAGTKIAI 1639 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI---DSKSASLTIKKVENTDAGIYKLRLEN 1364 P W I+ K K S LTI K E +D G Y L N Sbjct: 1640 EATVTGSPAAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAAN 1699 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + G + + +LDKP PP +I E S+ + W PE+ G S +I YV+E +++ Sbjct: 1700 DLGTDTAIIFIIVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEKRDMKR 1759 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 W V ++ + L + Y FR A NE+ S+ T+E Sbjct: 1760 NTWTKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTTSE 1804 Score = 283 bits (693), Expect = 5e-74 Identities = 281/1104 (25%), Positives = 452/1104 (40%), Gaps = 89/1104 (8%) Query: 1003 DQETSTMLVVKETIP---EFIRKLQDFEVKEKDVAILEVEINSETAD--VVWERDGEIIK 1057 D +T+ + ET + + L D +V EK A E +++ + D +VW +DG+ I Sbjct: 976 DLQTTQQMADLETFSAEGQDLTPLADAKVPEKIAATFECDVSRDVKDEDIVWMKDGQKIT 1035 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 P + K+ ++ G L I++TS D G+Y+ + D++ TA++ V E + L N Sbjct: 1036 PDE-KFQVKRDGRRLSLSIQDTSPEDSGQYTIKIGDKTQTADLKV--QAAEFVKPLNNTS 1092 Query: 1118 VNKGNKA-TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 + ++ E EL+ +W+KD I +++ DGKK+KL ++D +D G + Sbjct: 1093 AAEYDETIVLECELSNELVPCQWYKDDVLITVGPKVEVIDDGKKRKLVLHDVRPEDTGNF 1152 Query: 1177 SCEVGNSKCTAILTVEEPSINFTL---RLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 C VG+ + +A L V+ I L PEF A T A L E+ + TW K Sbjct: 1153 RCVVGDKESSATLDVKASEIMKPLAEVTAPEF----AET-AVLECEVSHPKAEATWLKDG 1207 Query: 1234 SVIEDTE----KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 I E K+ ++SD +KR LII +DD E+TC + D ++ + V+V Sbjct: 1208 QPITPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEFTCKVGDNQTVANVNVKVPSITKP 1267 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 + D + + V L + P +W+ N K I K K LTI + Sbjct: 1268 LEDTTTAFE----TTVVLECEVDNEKAP-VKWMKNGKEITKMPKYLMESKGKKRRLTIFE 1322 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 D G Y C D + +P+P + EI S+ DEP Sbjct: 1323 TIPEDEGDY------TCVVGDESTVAVLAVEPAP--IEFLSEI--QSVQAVEDEP----- 1367 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + E + D E I +KN + + + + S + R + D+SD +E T Sbjct: 1368 ---AVFTCEISD-DNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTDVSDTAEFT- 1422 Query: 1470 YYKVIKETKIQS-------PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 K +T S PT+ LK++ E + + V V W GK + Sbjct: 1423 -CKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECETDVETADVAWLHKGKDI 1481 Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI-- 1580 E+ K ++ D GE +C +G+ + I + Sbjct: 1482 ------VEDNSKFVIKRKGRRHSLIVKDVSVEDAGEF--TCRIGVHETIAELIVEVEFLA 1533 Query: 1581 ---KQKHKV-GDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 K++ + GDE +T +E E V W K+G K++ I K + IK++ Sbjct: 1534 PLPKEQSAIPGDE--ITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKV 1591 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 + Y S AG + L V P P + + I + + Sbjct: 1592 DFDDDAVY----SFNAGDQKCDCNLNVSAPPKINVDPKLTNISVKAGTKIAIEATVTGSP 1647 Query: 1696 LELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753 +T ++ ++ + K+ + I K + + + A N +G A Sbjct: 1648 AAVTTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAANDLGTDTA- 1706 Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK- 1812 I+ LD P ESV + W E +GGSP+I+Y +E K++ K+ Sbjct: 1707 ----IIFIIVLDKPQPPTSLSITETTP-ESVTLVWTAPEDDGGSPVIEYVIE-KRDMKRN 1760 Query: 1813 -WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 W R+ KL Y FR+ A NE+GTS P+T+ + +T P P Sbjct: 1761 TWTKVDTTSELTCRVPKLVEGNEYLFRVSATNELGTSEPFTTSEPVTAKYQFDVPHAPSK 1820 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 S+ +TL WT P+ NGGS +T YIIE K W KI + ++++ Sbjct: 1821 PETSDVIQTEMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKDLI 1880 Query: 1932 EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 E FR+ A N G S P+E S + + VP PP P V + SW P Sbjct: 1881 EGTSYEFRVYAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQP-TCENVNKTTITVSWTPP 1939 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 E DGG+P+ GY I DV++ W++ + V L F + DL++ Y RI A N G+ Sbjct: 1940 EDDGGSPVTGYVIERCDVSRGRWVKCNRDKVTELTFTVSDLTDGGQYQFRISAENAAGVG 1999 Query: 2051 EPLESDEPFKV-IPGEGSHADEEP 2073 +P + F +P + A +P Sbjct: 2000 QPSPTSATFTAKLPFDAPGAPGKP 2023 Score = 277 bits (679), Expect = 2e-72 Identities = 205/786 (26%), Positives = 342/786 (43%), Gaps = 31/786 (3%) Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 ++ K G + V Y P P W + + +K H + ++++++T+K VE Sbjct: 8177 FDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEK 8236 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411 + G Y + L+N G +++ V + D+P PP P + + S++ + W P + G S Sbjct: 8237 ANGGRYTINLKNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSESTVTLSWSPPSDDGGSR 8296 Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I YVV+ + T+W V I + LK N Y+FR A N+ S E Sbjct: 8297 IFTYVVQKRGEIETKWKHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQS 8356 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP-QPKVTWYRDGKKLKTAKAT 1528 + P+ K I GG P V R + KAT Sbjct: 8357 ITPQGQYNVPDPPSAPKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKAT 8416 Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQK 1583 Y + A N G E S V ++ V N D + + Sbjct: 8417 LTPTPDMTFRASRLIRGTEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFE 8476 Query: 1584 H----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 + G + + + P P V W +NG+ ++ I + + + + +R+ Sbjct: 8477 KVITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTD 8536 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 S Y I ASN AG +V VT+ V D PS P+GP+ + ++ VT+ W P DDGG +T Sbjct: 8537 SGDYVIRASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPIT 8596 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y +EK E W V+ D T+ + KL E+ EY FRV A+N +G SE LESE I+ Sbjct: 8597 GYVLEKREGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPLESERII 8655 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXX 1816 K DVP I ++SV +TW +++GG+P+ Y VE ++ G+ W Sbjct: 8656 PKGDYDVPD-QPGKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRT 8714 Query: 1817 XX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFV 1873 R+ +LS Y+FR+ A N+ G S P + + + + + P + Sbjct: 8715 SYKPVMDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQF 8774 Query: 1874 VSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIK 1931 T R+ TL + P S +P ++++ K V G+ T +V + ++ + Sbjct: 8775 RDVITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTN--KDAR 8832 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 D + I N G T +V L+K PS P P+++ + + V +W P+ Sbjct: 8833 RTDSGTYTIKISNKAGTDTATIRVAV-LDK----PSAPEGPIKVTSITCDSVTLAWEPPK 8887 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DGGA + GY + R+ + W V +++ ++ + L + +Y+ R+ A ++ G SE Sbjct: 8888 DDGGADITGYILERREPDQFRWTRVTST-LSSPRYAVTGLKDGRSYLFRVRAVSKYGESE 8946 Query: 2052 PLESDE 2057 PLE+++ Sbjct: 8947 PLETED 8952 Score = 254 bits (621), Expect = 3e-65 Identities = 178/696 (25%), Positives = 301/696 (43%), Gaps = 27/696 (3%) Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVK 1431 ++L KP P P + + +S+ + W+ PE+ G S I YV+E +E + W + + Sbjct: 7668 SVLVKPPYGRPSPPVVTDFTKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQ 7727 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 +I K + ++++LK + Y FR A+N+ I S+ +E + + SP E + NI Sbjct: 7728 SILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDGSELATAKSKFGVPSPPGEPTISNI 7787 Query: 1492 TTEPNEDIELT--CIFGGVPQPKVTWYRDGKKLKTAKATYENR----XXXXXXXXXXXXX 1545 T + + + T GG P T R + T + Sbjct: 7788 TAK-SVTLNWTPPSSDGGSPVTGYTVER-ADRFSTRWVPVNSHPIKDTKMDIHDLPATGS 7845 Query: 1546 XXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 ++ +A N G + + +G+ P + +VG + + + P P Sbjct: 7846 YQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDTYKYHDTMVVRVGATFNLDVPFKATPKP 7905 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 V W K+G+ L+ I T ++ +++ IK R + ++ SNTAG+ ++ + ++V Sbjct: 7906 TVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSNTAGSDAITIRVQV 7965 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 D+P +P GP++ ++I + + WK P D GG +T Y IE+ E D W ++ D Sbjct: 7966 LDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTTRALD 8025 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDN 1781 T + L E Y+FRV A N +G SE LE+ E I +K DVP + + Sbjct: 8026 T-TVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDVPE-APSKPLVTNVTS 8083 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WK--XXXXXXXXXARIQKLSINTTYQFR 1838 +SV + W + +GG+PI Y +E K+ W RI +L Y+FR Sbjct: 8084 DSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRIPRLMRGEEYEFR 8143 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 + A N G T I T P F + + P + +P Sbjct: 8144 VSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAV 8203 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 + + + +K + +I T ++N+++ + + I+ +NT G ES V Sbjct: 8204 TWSFDGRPLKPSAHIRIDT-SNRASTITVKNVEKANGGRYTINLKNTAG----AESLDVE 8258 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + P PP PLE+ V + V SW P DGG+ + Y + R +T W V K Sbjct: 8259 VRVFDR-PGPPRGPLEMSNVSESTVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKHVNK 8317 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + L + + L EN Y R+ A N+ G S+PLE Sbjct: 8318 DYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLE 8353 Score = 247 bits (604), Expect = 3e-63 Identities = 194/705 (27%), Positives = 300/705 (42%), Gaps = 42/705 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 D P PGKP + E + + + I W PE+ G S + +VVE +E ++ W+ V T T+T Sbjct: 2317 DAPGAPGKPQVTEYNITKMTITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTET 2376 Query: 1439 S--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEP 1495 + + L S Y+FR A N ASE ++ K + +P+ KP +T+ Sbjct: 2377 TLIVTGLTEGSEYQFRVIAENPAGPGPASEPSDLQKA--KLPFDAPSAPGKP--EVTSAD 2432 Query: 1496 NEDIELTCIF----GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 +ELT GG P +T Y KK T K T + K Sbjct: 2433 KTQMELTWAVPDSDGGSP---ITGYIIQKKENTGKWTQSLKTTTTETTATIKSLIEKKEY 2489 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV----TAVIEGIPPPEVIWY 1607 F V + + I+ G ++ T++ PPE Sbjct: 2490 EFRV-AAVNLAGTGPFSEPSDYQIAKAPYDVPGPPGKPTILEVDSTSMTITWTPPETDGG 2548 Query: 1608 K--NGNKLEN-DKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAGT------ 1653 G +E D+ + TK K + I I +LK + ++ + A N AG Sbjct: 2549 SPVTGYVVEKRDRVSSRWTKVKETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEP 2608 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 S YD P P P I ++ + +T+ W PP DDGG ++ Y +EK + D RW Sbjct: 2609 SDQRRAKPPYDVPGPPGIPDIS-DVDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRW 2667 Query: 1714 IKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXX 1771 K D E T + L E YMFRV A+N G E+ L ++P K D P Sbjct: 2668 TKAHKEDLVTELTLTVYDLTEGTNYMFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPP 2727 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX--XXARIQK 1828 +D S+++TW P + +GGS + Y +E + + + KW + Sbjct: 2728 PPTPTH-VDRTSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEISFTVTG 2786 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 L+ + Y FR+ A N+ G P D + P P V S+ T SV L+W+ Sbjct: 2787 LTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETSVHLEWSP 2846 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 P +NGG+ IT YI+E K WTK G ++++KE +E FR+ A N G Sbjct: 2847 PSNNGGAEITEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVIAVNPAGP 2906 Query: 1949 SLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 P+++ + K VP P P + +++ +T W P DGG+P+ GY + ++D Sbjct: 2907 GSPSDACKPFVAKPPYDVPDAPGKPAPSDLSPTSVTLT-WTPPPSDGGSPITGYTVEMKD 2965 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 T W + + ++ + DL E Y R+ A N+ G S+P Sbjct: 2966 KFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKP 3010 Score = 244 bits (598), Expect = 2e-62 Identities = 191/811 (23%), Positives = 346/811 (42%), Gaps = 45/811 (5%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 P I+ + + I V A T +L V I T V W + ++D + + Sbjct: 8766 PKIDLGSQFRDVITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAV 8825 Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L + D YT + + T ++V V++ P + I S VTL Sbjct: 8826 LTNKDARRTDSGTYTIKISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDS-VTL--- 8881 Query: 1311 YQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 A+ P D+ +I+ + + + T+ + S + +++ + ++++R Sbjct: 8882 --AWEPPKDDGGADITGYILERREPDQFRWTRVTSTLSSPRYAVTGLKDGRSYLFRVRAV 8939 Query: 1364 NNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + G ++ +E IL +KP PG P + SI + W P + G + I Y++ Sbjct: 8940 SKYGESEPLETEDAILIKSAFEKPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYIL 8999 Query: 1418 EYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 E +E T W+ K + + L Y FR A NE + S+T+ ++ Sbjct: 9000 EIKETRGTRWLRATRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSA--PIVS 9057 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYEN 1531 +T I+ +PLK+++ + + + L C P +V W +DG ++ + + Sbjct: 9058 KTPIELAEFVEPLKDVSAKAGKIVTLECRISN-PNAEVKWMKDGFQIFGYDRVNEIKEGQ 9116 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 R Y C + G+ TSC + + P I + K G+ Sbjct: 9117 RRAITLRNVGDRDTGKYSC----ECGKQSTSCWLSVTAPPTIDVKAYKDVVVVKTGNTLR 9172 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + G P P+V W+++ ++ D +I T++ + I I+ + R + K++I +N A Sbjct: 9173 LLVPYTGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEA 9232 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G + + + V D P P GP+ + ++ R V++ W+PP DDGG + Y +E+ E + Sbjct: 9233 GQETAIIRVNVIDVPGPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRR 9292 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXX 1770 W V++ V + + L+E EY FRV A+N G L EP+VI VP+ Sbjct: 9293 MWTSVSNYVSHV-PFTVSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPT-P 9350 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK--XXXXXXXXXARIQ 1827 + + + +TW +GG PI Y +E ++ K+W I+ Sbjct: 9351 PGKPEISNVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIK 9410 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKW 1886 L+ + Y+FRI A N+ G P + ++ P+ P ++ + T+ SV+L W Sbjct: 9411 GLTEGSNYEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATSVSLSW 9470 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946 + P ++GGS IT+YI+E + W V + + N+ E E FR++A N Sbjct: 9471 SAPSTDGGSEITHYIVERRLKGSYMWIDRTVVHDT--SCSVNNLVEDKEYTFRVTAVNAA 9528 Query: 1947 GVSLPTESQSVRLEKHATVP-SPPTAPLEIR 1976 G S + +P + P+ +EI+ Sbjct: 9529 GNESDPSRASESFVAESQLPGAAPSILIEIQ 9559 Score = 237 bits (581), Expect = 2e-60 Identities = 199/818 (24%), Positives = 349/818 (42%), Gaps = 50/818 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVI 753 L + +V+ G + V ++E A+L + + ++++PL + + E+ + Sbjct: 1139 LVLHDVRPEDTGNFRCVVGDKESSATLDV---------KASEIMKPLAEVTAPEFAETAV 1189 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEG 812 L +V +P+ TW K+ +P+ T + + ++ + + ++ +K +N+E Sbjct: 1190 LECEV-SHPKAEATWLKDGQPI----TPEELTSKKYEVVSDGRKRRLIIHDVVKDDNAEF 1244 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + TV N + P ++ T + T+ L V P + W +N + Sbjct: 1245 TCKVGDNQTV---ANVNVKVPSITKPLEDTTTAFETTVVLECEVDNEKAP-VKWMKNGKE 1300 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 I+ G+ L I E D GDY CV G S A + ++ + F+ Sbjct: 1301 ITKMPKYLMESKGKKRRLTIFETIPE-DEGDYTCVV----GDESTVAVLAVEPAPIEFLS 1355 Query: 933 HLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXX 990 +Q S + E + + C+ S W N++EI D + E + G+ Sbjct: 1356 EIQ-SVQAVEDEPAVFTCEISDDNAEVIWLKNEEEIKPDDEKYEFVVSGKKRGLKIKSTD 1414 Query: 991 XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVVW 1049 D C KD+ +S L V E IP L+D +++E + + E E + ETADV W Sbjct: 1415 VSDTAEFTCKTKDKTSSASLTVTEHIPTISHTLKDVKIEEGSNEVVFECETDVETADVAW 1474 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 G+ I +K+ +++G L +++ SV D GE++C + AE+ +VE+ E Sbjct: 1475 LHKGKDIVEDNSKFVIKRKGRRHSLIVKDVSVEDAGEFTCRIGVHETIAEL-IVEV--EF 1531 Query: 1110 ITRL-QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 + L + Q G++ TFE+ELTK V W KDG +I+ +++++ DGKK KL I Sbjct: 1532 LAPLPKEQSAIPGDEITFEVELTKDTEDVFWLKDGQKIKPGDNVKIVKDGKKHKLIIKKV 1591 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEP-SINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 D DD YS G+ KC L V P IN +L I V A T + + V Sbjct: 1592 DFDDDAVYSFNAGDQKCDCNLNVSAPPKINVDPKLTN-ISVKAGTKIAIEATVTGSPAAV 1650 Query: 1228 T-WYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 T W K + IE T++F + + + L I K D YT + T + + Sbjct: 1651 TTWSKGDTPIESTKRFKIEAGKGPKASIRLTIDKTERSDLGTYTLTAANDLGTDTAIIFI 1710 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLL--VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + VTL+ P E+++ + +K+ TK S+ Sbjct: 1711 IVLDKPQPPTSLSITETTPESVTLVWTAPEDDGGSPVIEYVIEKRDMKRNTWTKVDTTSE 1770 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTI---LDKPSPPGKPNILEIDSS 1395 K VE + ++++ N G ++ VT D P P KP ++ + Sbjct: 1771 LTCRVPKLVEGNEY-LFRVSATNELGTSEPFTTSEPVTAKYQFDVPHAPSKPETSDVIQT 1829 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRA 1453 + + W P+ G S + Y++E +E D T W+ + T T+ + +++L +SY FR Sbjct: 1830 EMTLTWTPPDFNGGSEVTGYIIERKEADKTRWVKITKETVTELTFRVKDLIEGTSYEFRV 1889 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 YA+N+ S SE + K + P + +N+ Sbjct: 1890 YAINKAGTSKPSEPSTPTKAKAPYDVPGPPAQPTCENV 1927 Score = 236 bits (578), Expect = 4e-60 Identities = 169/605 (27%), Positives = 280/605 (46%), Gaps = 42/605 (6%) Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 +E+ I+ G + + Y+A P P W N ++K ++ +LT + E Sbjct: 8475 FEKVITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAER 8534 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411 TD+G Y +R N G V + V ++D PSPP P ++++ S+ + + W P + G S Sbjct: 8535 TDSGDYVIRASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSP 8594 Query: 1412 IIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I YV+E +E W +V + I T + L + Y+FR A N + + SE E Sbjct: 8595 ITGYVLEKREGGYGSWTNVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGV---SEPLES 8651 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVPQPKVTWYRDGKKLKTAK 1526 ++I + P +K + T ++ + LT GG P VT Y K+ + Sbjct: 8652 ERIIPKGDYDVPDQPGKIK-VDTIQSDSVSLTWSRPQRDGGAP---VTGYIVEKRERGQP 8707 Query: 1527 ATYENRXXXXXXXXXX--------XXXXXYKCIAFNDHG---EVETSCVVGIQQ---KPV 1572 NR ++ A N G T+ V +++ P Sbjct: 8708 EAGWNRTSYKPVMDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPK 8767 Query: 1573 ITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 I + ++ D+ + G + + I G P P V W + ++++ + +T ++V+ Sbjct: 8768 IDLGSQFRDVITV-RAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVL 8826 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690 K+ +R+ S YTI+ SN AGT + + + V DKPS PEGP+ + I+ +SVT+ W+PP Sbjct: 8827 TNKDARRTDSGTYTIKISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDSVTLAWEPP 8886 Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 DDGG ++T Y +E+ EPD RW +V Y + L + Y+FRV A + G S Sbjct: 8887 KDDGGADITGYILERREPDQFRWTRVTST-LSSPRYAVTGLKDGRSYLFRVRAVSKYGES 8945 Query: 1751 EALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808 E LE+E I+IK+A + P + ++S+ ++W P +GG+ I +Y +EIK+ Sbjct: 8946 EPLETEDAILIKSAFEKPP-APGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKET 9004 Query: 1809 EGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIG------TSLPYTSDDKITIG 1860 G +W R+ LS Y+FR+ A NE G TS P S I + Sbjct: 9005 RGTRWLRATRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSAPIVSKTPIELA 9064 Query: 1861 KTLTP 1865 + + P Sbjct: 9065 EFVEP 9069 Score = 235 bits (576), Expect = 7e-60 Identities = 189/734 (25%), Positives = 297/734 (40%), Gaps = 33/734 (4%) Query: 1358 YKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 +++ +N G + T KP P +P+I ++ +S+ + W PE+ G S + Y+ Sbjct: 5645 FRVVAKNKAGASQPSSVATFSIKPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYI 5704 Query: 1417 VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 VE +E D W+ IT T ++Q+L Y FR A N+ + ASE ++ Sbjct: 5705 VERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVIAK 5764 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDI-ELTCIFGGVPQPK-VTWYRDGKKLKTAKATYENR 1532 + V+ + NIT E GG P V +D ++ + Sbjct: 5765 PPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEMKDKFGVRWTSLGKPTK 5824 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIK---QKHKVGD 1588 ++ A N GE E IQ KP++ D+ +K + Sbjct: 5825 TSFKVTNLKTGSEYEFQVRAENKAGEGEP-----IQSTKPIVAKDAYDVPDAPEKPEPSS 5879 Query: 1589 EWLVTAVIEGIPPP-----EVIWYKNGNKLENDKEYNITTKEKT--SVIRIKELKRSHSS 1641 + + PP ++ Y K + + T++ + + + +L+ Sbjct: 5880 LTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEY 5939 Query: 1642 KYTIEASNTAGTSSVEVTL------KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 + + A N AG S K Y P P P I+ S T+ WK P DGG Sbjct: 5940 TFRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASN-ITETSATLNWKAPTSDGG 5998 Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754 +T Y IEK E + RW D ++ ++ L EY FRV A N G + ++ Sbjct: 5999 SPITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAAVNKAGSGKPSVP 6058 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW 1813 SE + P N SV ++W P +GGS IIDY VE K +W Sbjct: 6059 SETFKAQPPYAAPEAPSAPVIEEVTAN-SVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRW 6117 Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 + KL QFR+ A N+ G P S +T+ T P P Sbjct: 6118 TEVNRTPETTFTVPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPT 6177 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 E + S+T++W+ P+++GGS ITNYI+E K W ++ T S + + +KE Sbjct: 6178 AVEVDAVSITVRWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKEN 6237 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992 + FR+ A N G P+ K TVPS P AP ++ V + + +W Sbjct: 6238 QTLEFRVIAVNKAGEGKPSSVGGPFTTKATYTVPSAPGAP-DVSNVKATSMTVTWTKSIS 6296 Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 DGG+P+ GY + DV+ W+ V +V + + L E Y R+ A N G S+P Sbjct: 6297 DGGSPITGYVLEKCDVSTGRWVPVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKP 6356 Query: 2053 LESDEPFKVIPGEG 2066 E + + P G Sbjct: 6357 SEPSKAYIAKPPYG 6370 Score = 235 bits (575), Expect = 1e-59 Identities = 196/722 (27%), Positives = 301/722 (41%), Gaps = 37/722 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKT 1436 D PS PG P+I +I S+++ + W PE+ G + II ++VE +E +T W+ + + T+T Sbjct: 6773 DLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISRFDFTET 6832 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 S+ LK + Y FR A N++ I SE T K KE +SP+ + NIT E + Sbjct: 6833 TFSVTGLKDGNDYEFRVAAKNKIGIGKFSEPTRPTKA-KE-PYESPST-PDVSNITGE-S 6888 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX-----XXXXXXXXYKCI 1551 + T P + + ++ + T NR ++ I Sbjct: 6889 MTLNWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAEYEFRVI 6948 Query: 1552 AFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP-----PEVI 1605 A N G S V KP T I + +V D T I PP ++ Sbjct: 6949 AENKAGLGRPSQVTHPFTAKPPYT--TPGIPDQPEVEDVTATTITISWSPPSYDGGSKIT 7006 Query: 1606 WYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVT 1659 Y +K + + I + + LK ++ + A N AG S VT Sbjct: 7007 GYTIESKSDATMRWVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVT 7066 Query: 1660 LK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 K YD P P+ P + I+ S + W P DGG +T Y I+K + + RW+K + Sbjct: 7067 CKPPYDPPPPPDAPDVY-NITPTSAALTWSTPRQDGGSPITGYVIDKKDKYSTRWVKADE 7125 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXX 1777 V + I+ L +Y FRV A N G + + E K VP Sbjct: 7126 VPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPD-APSPPSVS 7184 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXXXXARIQKLSINTT 1834 I S+ ++W P +GGS + Y VE ++ +W ++ LS + Sbjct: 7185 DITPSSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLSEDRK 7244 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y+FR+ A N G P PS P + S + L+WT P ++GG Sbjct: 7245 YEFRVSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATNVDSTELVLEWTAPVADGG 7304 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 SPITNY+IE + G W+KI + + +K DE FR+ AEN VG+ P+++ Sbjct: 7305 SPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAENKVGLGRPSDN 7364 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS--WGTPEWDGGAPLLGYNIAIRDVTKTM 2012 + K P AP +++ G+ S W P DGG+P+ GY + +D Sbjct: 7365 TESIVAKPPY--DTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSAR 7422 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV-IPGEGSHADE 2071 W V +V V + DL E Y R+ A N G+ +S +P + P + A Sbjct: 7423 WTRVNRVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPVDAPSAPL 7482 Query: 2072 EP 2073 EP Sbjct: 7483 EP 7484 Score = 233 bits (570), Expect = 4e-59 Identities = 186/700 (26%), Positives = 289/700 (41%), Gaps = 37/700 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 D P P P I ++ + S+ I W P + G S + Y++E +E +++W+ V Sbjct: 5472 DVPESPDTPKISDVTNDSMVISWQPPYSDGGSKVTEYIIEKKEPYSSKWVPVTKTRDLSY 5531 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT------ 1492 I LK N Y FR AVN+ S+ S T K + S + +++ Sbjct: 5532 KITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVPSQPHSLKIADVSPTSLTL 5591 Query: 1493 --TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550 +EP+ D + G + + K R + T + ++ Sbjct: 5592 EWSEPDSD-GGDNVSGYIIEKK---DRFSPRWTPVNQTAISDTKFKVTGLKDGQDCEFRV 5647 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608 +A N G + S V KP S DIK+ ++ V W G P I Sbjct: 5648 VAKNKAGASQPSSVATFSIKPPDAPSRPDIKKVTENSVTLSWSPPESDGGSPVTSYI--- 5704 Query: 1609 NGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYD 1664 + E D++Y + + +++L H ++ + A N AG E + V Sbjct: 5705 -VERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEASKSVIA 5763 Query: 1665 KP--SKPEGPVIM--REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720 KP P+ PV + I++ S + W PP+DDGG +T Y +E + RW + Sbjct: 5764 KPPYDVPDVPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVEMKDKFGVRWTSLGKPT 5823 Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXI 1779 + ++ + L EY F+V A+N G E ++S +PIV K A DVP + Sbjct: 5824 K--TSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPD-APEKPEPSSL 5880 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKW--KXXXXXXXXXARIQKLSINTTYQ 1836 SV +TW P +GGS I Y VE K++ +W + L + Y Sbjct: 5881 TETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEYT 5940 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A N+ G S P K P P + S T S TL W P S+GGSP Sbjct: 5941 FRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASNITETSATLNWKAPTSDGGSP 6000 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQ 1955 ITNY IE + WT S + +++ E FR++A N G P+ S+ Sbjct: 6001 ITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAAVNKAGSGKPSVPSE 6060 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + + + P P+AP+ I V +N V SW P DGG+ ++ Y + +D W E Sbjct: 6061 TFKAQPPYAAPEAPSAPV-IEEVTANSVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRWTE 6119 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 V + T F + L E R+ A N+ G +P +S Sbjct: 6120 VNRTPETT--FTVPKLKEGDAVQFRVTAVNKAGPGKPSQS 6157 Score = 232 bits (567), Expect = 9e-59 Identities = 218/913 (23%), Positives = 368/913 (40%), Gaps = 52/913 (5%) Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 AG ++ TA +EPS + + P + T D +T Y Sbjct: 3584 AGPGEASDASASFTAKAPFDEPSAPGVPKASN--ITPTSVTLSWTAPDSDGGSPITEYIL 3641 Query: 1233 KSVIEDTEKFTLIS--DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE---VVEFP 1287 +S + + KF+ ++ V T ++ E+ + ++ + + ++ E V ++ Sbjct: 3642 ESKDKYSSKFSPVTRDTVTDLTFTVKNLKENGEYQFRVIAQNKAGPSEPSRETKVVAKYE 3701 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQA-FPQPNDE---WIVNSKIIKKCKHTKPSIDS-KS 1342 ++ ++R S ++ +D+ F + +I+ K K + T S DS Sbjct: 3702 FEVPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIEKKE-KSGRWTPVSSDSVDG 3760 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICW 1401 + T+K + + + +++ N G + ++ V P PG+P + +I+ +S + W Sbjct: 3761 TTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTVLTAKPPGAPGRPEVSDINKTSATVTW 3820 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 + G STI Y+VE +E W+ V K I + +L + Y FR A N + Sbjct: 3821 KPSSSDGGSTITGYIVEKREKGRDRWVPVNRKPINAVTMKVTDLTEKTDYEFRVIAENRI 3880 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVPQPK--V 1513 SE + K I ++ PT K P + LT GG P + Sbjct: 3881 GQGQPSEPSA--KFIAKSPFDVPTAPGAPKASDITPTS-LTLTWTPPTDDGGSPITNFII 3937 Query: 1514 TWY-RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 W + + K ++ IA N G+ E S + K Sbjct: 3938 EWKDKFSTRFTILKKDLFVELTFKVTGLKDKTEYTFRIIAENKEGQSEPSKETVVVAKYG 3997 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPP------EVIWYKNGNKLENDKEYNITTKEK 1626 I E + K T+V PP ++ Y K ++ + +T Sbjct: 3998 FDIPQEPSAPEVK---RLSPTSVELSWTPPRSDGGADITGYILEKKDKSGRWTPVTDSVD 4054 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + +K LK + ++ + A N AG S V KP P G + ++ + VT+ Sbjct: 4055 GTSFTVKGLKEGENVEFRVSAVNKAGQSKPSEVSLVAVKPPGPPGMPEVSDVDKNCVTLN 4114 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W PP DGG + Y +EK E + WI+V + T + L E +Y FRVIA+N Sbjct: 4115 WTPPTSDGGSTIIGYTVEKREKGRS-WIRVNRTLVNETTMTVSDLVEKNDYEFRVIAENK 4173 Query: 1747 VGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 VG E S V K DVP+ + + +TW P +++GGSPI Y +E Sbjct: 4174 VGPGEPSNPSIKFVAKAPFDVPAAPDAPEPSN-VTPTTATLTWTPPKRDGGSPITGYILE 4232 Query: 1806 IKQE-GKKWKXXXXXXXX--XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK- 1861 +K +W ++ L T YQFR+ A N+ G S P S + + I K Sbjct: 4233 MKDRFATRWTQVNTDSMTEVTCTLKTLKEGTEYQFRVIAVNKAGQSKP--SAETVVIAKH 4290 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 P P ++++T S++L W P+ NGGS +T Y IE K W+ I V Sbjct: 4291 PFDVPGAPSTPTITKATPNSISLAWRPPKVNGGSRVTGYYIEMKDEYRPRWSPINKVAIK 4350 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL--EIRMVG 1979 ++ + ++ + ++ FR+ AEN G P+ L+ AT P AP ++ + Sbjct: 4351 DTDYKVMDLTKNEKYYFRVKAENKAGQGKPS------LDTKATAKYPFDAPTIDDVSRIS 4404 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 W P DGGA + GY I +D W V + ++ F +++L E Sbjct: 4405 ETSAKIKWTPPSNDGGAEISGYIIEKKDRLAVKWSPVIEDTLDNTSFTVKNLREGEDVEF 4464 Query: 2040 RIYARNEIGLSEP 2052 R+ A N+ G +P Sbjct: 4465 RVSAVNKAGTGKP 4477 Score = 230 bits (563), Expect = 3e-58 Identities = 136/440 (30%), Positives = 200/440 (45%), Gaps = 13/440 (2%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSS----VEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 ++ LK ++ + A N AG S ++K D PS+P+ +++++ SVT+ Sbjct: 5633 KVTGLKDGQDCEFRVVAKNKAGASQPSSVATFSIKPPDAPSRPD----IKKVTENSVTLS 5688 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W PP DGG +T Y +E+ EPD + W+K T+ +Q L +Y FRVIA+N Sbjct: 5689 WSPPESDGGSPVTSYIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENK 5748 Query: 1747 VGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G A E S+ ++ K DVP I S + W P +GGSPI +Y VE Sbjct: 5749 AGLGGASEASKSVIAKPPYDVPD-VPVDLDVTNITKNSAELFWNPPMDDGGSPITNYVVE 5807 Query: 1806 IKQE-GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864 +K + G +W ++ L + Y+F++ A N+ G P S I Sbjct: 5808 MKDKFGVRWTSLGKPTKTSFKVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYD 5867 Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P P S T SVTL W+ P S+GGS IT YI+E K W Sbjct: 5868 VPDAPEKPEPSSLTETSVTLTWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTT 5927 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 + +++E E FR+ AEN G S P+E + + +K VP P +P E + Sbjct: 5928 LTLNDLREGSEYTFRVIAENKAGQSKPSEPCRPFKAKKPYGVPDTPGSP-EASNITETSA 5986 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 +W P DGG+P+ Y I R+ W + DV+ F +RDL H Y R+ A Sbjct: 5987 TLNWKAPTSDGGSPITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAGHEYSFRVAA 6046 Query: 2044 RNEIGLSEPLESDEPFKVIP 2063 N+ G +P E FK P Sbjct: 6047 VNKAGSGKPSVPSETFKAQP 6066 Score = 230 bits (562), Expect = 4e-58 Identities = 196/700 (28%), Positives = 294/700 (42%), Gaps = 41/700 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 P P P++ +I SS+ + W+ P + G ST+ Y+VE +E W+ V I +T Sbjct: 7175 PDAPSPPSVSDITPSSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTF 7234 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + +L + Y FR A N + SE + +V K +P Sbjct: 7235 KVNDLSEDRKYEFRVSAENAAGVGKPSEVS-LPRVAKSPYDAPSAPGRPTATNVDSTELV 7293 Query: 1499 IELTCIF--GGVPQPK-VTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAF 1553 +E T GG P V RD L+ +K + Y + IA Sbjct: 7294 LEWTAPVADGGSPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAE 7353 Query: 1554 NDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP-----PEVIWY 1607 N G S I KP D + +V +A +E PP V Y Sbjct: 7354 NKVGLGRPSDNTESIVAKP--PYDTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGY 7411 Query: 1608 KNGNKLENDKEY---NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTL 1660 K + + N +T+++ + +LK ++ + A N AG + S + T+ Sbjct: 7412 FVERKDQYSARWTRVNRVPVTETNMV-VGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTV 7470 Query: 1661 --KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 D PS P P I I+ +S T+ W P DGG +T Y +E+ +P RW Sbjct: 7471 IKDPVDAPSAPLEPTIA-SITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARW---TP 7526 Query: 1719 VDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXX 1776 ++R +T C I L E EY FRV+A N G S S+P V K+ DVP Sbjct: 7527 IERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPSKPQVT 7586 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINT 1833 + SV + W P +GGSPI Y V+ K+ +W + L+ + Sbjct: 7587 E-VKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQKS 7645 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 Y+FR+ A N+ G P + + + PS P VV++ T SVTL+W PES+G Sbjct: 7646 EYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPP---VVTDFTKTSVTLQWNPPESDG 7702 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 GS IT Y++E K W + E ++++KE + FR+ A N G+ P++ Sbjct: 7703 GSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSD 7762 Query: 1954 SQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 + K VPSPP P I + + V +W P DGG+P+ GY + D T Sbjct: 7763 GSELATAKSKFGVPSPPGEP-TISNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTR 7821 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 W+ V + K +I DL +Y RI A N G S+P Sbjct: 7822 WVPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKP 7861 Score = 228 bits (557), Expect = 1e-57 Identities = 146/462 (31%), Positives = 211/462 (45%), Gaps = 16/462 (3%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPVIMREISRESV 1683 + I +L + ++ + A N AG S V K+ +D P P P + E + + Sbjct: 2277 LTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKAKLPFDAPGAPGKPQVT-EYNITKM 2335 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 TI W PP DGG +T + +E+ E ++RW++V T + L E EY FRVIA Sbjct: 2336 TITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIVTGLTEGSEYQFRVIA 2395 Query: 1744 QNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 +NP G A E + K D PS D + +TW + +GGSPI Y Sbjct: 2396 ENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSA-DKTQMELTWAVPDSDGGSPITGY 2454 Query: 1803 KVEIKQEGKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 ++ K+ KW A I+ L Y+FR+ A N GT P++ I Sbjct: 2455 IIQKKENTGKWTQSLKTTTTETTATIKSLIEKKEYEFRVAAVNLAGTG-PFSEPSDYQIA 2513 Query: 1861 KT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919 K P P + E S S+T+ WT PE++GGSP+T Y++E + WTK+ Sbjct: 2514 KAPYDVPGPPGKPTILEVDSTSMTITWTPPETDGGSPVTGYVVEKRDRVSSRWTKVKETS 2573 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978 + I ++KE ++ FR+SAEN GV P+E S R + VP PP P +I V Sbjct: 2574 IEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPPYDVPGPPGIP-DISDV 2632 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD-VNTLKFNIRDLSENHTY 2037 N + +W P DGGA +LGY + D + W + K D V L + DL+E Y Sbjct: 2633 DKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHKEDLVTELTLTVYDLTEGTNY 2692 Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 M R+ A N G+ E + +P K P P T V Sbjct: 2693 MFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPPPPTPTHV 2734 Score = 227 bits (556), Expect = 2e-57 Identities = 181/705 (25%), Positives = 296/705 (41%), Gaps = 33/705 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 P P P I E+ ++S+ + W+ P G S II YVVE ++ + W V +T ++ Sbjct: 6071 PEAPSAPVIEEVTANSVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRWTEVNRTPETTFTV 6130 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-----IKETKIQSPTVEKPLKNITTE- 1494 LK + +FR AVN+ S+++ + + E Q VE +IT Sbjct: 6131 PKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVEVDAVSITVRW 6190 Query: 1495 --PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 P D + I + + K + K++ T +++ ++ IA Sbjct: 6191 SAPKNDGG-SRITNYILEMKEQFSSFWKRVSTKESS---ELTYQVTGLKENQTLEFRVIA 6246 Query: 1553 FNDHGEVETSCVVG-IQQKPVITISNE----DIK--QKHKVGDEWLVTAVIEGIPPPEVI 1605 N GE + S V G K T+ + D+ + + W + G P + Sbjct: 6247 VNKAGEGKPSSVGGPFTTKATYTVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYV 6306 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-D 1664 K N +TS++ + +L+ + + A N AG S K Y Sbjct: 6307 LEKCDVSTGRWVPVNRVPLRETSLV-VDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIA 6365 Query: 1665 KP--SKPEGPVI--MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DV 1719 KP P+ P + I + +T+ W PP DGG + Y IEK + + RW + + Sbjct: 6366 KPPYGLPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRET 6425 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXX 1778 D++ Y +++L E E FRV A+N G E+ VI K+ DVPS Sbjct: 6426 IHDMQ-YTLRELTEGGEVEFRVAAENKAGVGPFSETTGTVIAKSPFDVPS-APGTPKISD 6483 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA--RIQKLSINTTYQ 1836 I S+ +TW P +GG+ I ++ +E++ +W + LS +Y+ Sbjct: 6484 ITGTSLVLTWTPPSSDGGTEITNFIIELRDRYGRWTRVNRTQVLKTGFNVMNLSEGDSYE 6543 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A N++G P S K+T + P+ P +S T+ S TL W+ P +GGS Sbjct: 6544 FRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQISNVTADSATLTWSPPRDDGGSS 6603 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955 IT Y IE K WT++ + + + + +E FR+ A+N G S P+E ++ Sbjct: 6604 ITGYFIEKKDKFSPRWTRVNHDAVTDTKFTVPALVPGEEYQFRVVAQNKAGASKPSEPTE 6663 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 S + P P AP + + + +T W P DGG+ + GY + +D W Sbjct: 6664 STLVRSPFNEPGAPGAPETSNVTETTLTLT-WTPPFSDGGSRITGYYVEKKDRMSLRWSP 6722 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 V K + L+E Y R+ A N+ G S+P P K Sbjct: 6723 VNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVK 6767 Score = 226 bits (553), Expect = 5e-57 Identities = 135/437 (30%), Positives = 200/437 (45%), Gaps = 11/437 (2%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 T + TS +K L+ ++ + A N AGT + KP P G I + S Sbjct: 4445 TLDNTS-FTVKNLREGEDVEFRVSAVNKAGTGKPSSIATLAAKPPGPPGVPEASNIDKIS 4503 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 T+ W PP DGG ++T Y +EK E +RW+KV T + L E Y FRV Sbjct: 4504 ATLTWTPPESDGGSKVTGYIVEKRERGLDRWMKVNRAPVKDVTLKVLDLTEKKHYEFRVT 4563 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 A+N G E +S + K DVP I S ++W P +GGSPI Y Sbjct: 4564 AENKAGLGEPSDSVSFIAKPPYDVPG-APSTPVASDISPTSATLSWSPPYSDGGSPITSY 4622 Query: 1803 KVEIKQE-GKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 +E+K +W K ++ L N YQFR+ A N+ G P + +T Sbjct: 4623 TIEMKDRFSSRWTKAKDMVTEETFQLNSLKENNEYQFRVIAENKAGPGEP-SPTVNVTAK 4681 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 P P V ++ SV L W +P+S+GGS I YIIE K VKG+ WT++ T Sbjct: 4682 YEFDTPQAPAEPDVRRTSPTSVELSWVKPKSDGGSKIKGYIIE-KKVKGEPWTQVTTDTV 4740 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + E +++ FRISA N G P+ + + + P PP P E+ V Sbjct: 4741 DGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVVIAFKP----PGPPGTP-EVSDVDK 4795 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 V +W P+ DGG+ ++GY + R+ + W+ + + V + +I DL E + Y R Sbjct: 4796 TSVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREVTMSITDLVEKNEYEFR 4855 Query: 2041 IYARNEIGLSEPLESDE 2057 + A N++G EP E Sbjct: 4856 VIAENKVGPGEPSSPSE 4872 Score = 224 bits (548), Expect = 2e-56 Identities = 174/704 (24%), Positives = 288/704 (40%), Gaps = 36/704 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436 D+P PP P +D +SI++ W P++ G S + Y++E ++ +W V I + Sbjct: 2721 DEPGPPPPPTPTHVDRTSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEI 2780 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 ++ L ++ Y FR AVN+ S ++ K + P+ + TE + Sbjct: 2781 SFTVTGLTEDAIYDFRVSAVNKAGEGPPSLPSDTLKAKLPFDVPGAP-STPVPSDITETS 2839 Query: 1497 EDIELT--CIFGGVPQPK-VTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCI 1551 +E + GG + + +D + KA T + ++ I Sbjct: 2840 VHLEWSPPSNNGGAEITEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVI 2899 Query: 1552 AFNDHGEVETS--CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----V 1604 A N G S C + + P D K D + + PPP + Sbjct: 2900 AVNPAGPGSPSDACKPFVAKPPYDV---PDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPI 2956 Query: 1605 IWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTSS----VEV 1658 Y K + + T+E S + + +LK ++ + A N AG S + V Sbjct: 2957 TGYTVEMKDKFSTRWTKATRELISETTVVLPDLKEKEEYQFRVIAENKAGQSKPSPELHV 3016 Query: 1659 TLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 T K ++ P P + RE S S T++W PP DGG E+T Y +EK E + RW V Sbjct: 3017 TAKYPFETPQAPTIDNVTRE-SPTSATVKWSPPKSDGGSEITGYVLEKKEKMSPRWSPVI 3075 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 + + + ++ ++ L + FRV A N G +P + T P Sbjct: 3076 ESETET-SFTVKGLPDGENVEFRVSAVNKAG-----TGKPSQVATLSAKPPGAPDAPEVS 3129 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX--XXARIQKLSINTT 1834 ID S + W +GGS I Y +E +++G+ +W ++ L+ Sbjct: 3130 DIDRTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQ 3189 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y+FR+ A N++G P + T P P + S+ T S TL W P+S+GG Sbjct: 3190 YEFRVIAENKVGPGEPSNPSARFTAKAPFDEPEAPYSLAASDITPTSATLSWLPPDSDGG 3249 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 SPI Y +E K WTK+ + N++E +E ++R+ AEN G S P+ Sbjct: 3250 SPILGYTLETKDRFSSRWTKVNKGLLQETSFKVTNLEENNEYVYRVIAENKAGPSKPSNE 3309 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 + P P + ++ V+T W P +DGG+P+ GY + +++ T W Sbjct: 3310 CKFIAKHQFETPEAPGNVVAKDTTPTSTVIT-WREPSFDGGSPITGYTVEMKEPYSTRWT 3368 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 K + F ++ L EN Y R+ A N G +P P Sbjct: 3369 PANKEPIEETTFLVKRLKENENYQFRVVAHNLAGPGKPKAPKPP 3412 Score = 220 bits (538), Expect = 3e-55 Identities = 185/725 (25%), Positives = 290/725 (40%), Gaps = 40/725 (5%) Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 +D +M D P PP KP I+ ++I I W PEN G S + Y+VE E W+ Sbjct: 2206 SDNKMAKAPYDVPGPPSKPTTENINKTTITITWTPPENDGGSPVTGYIVEKCEGARGRWV 2265 Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 +T+ +I +L + Y+FR A N + ++ K K+ Sbjct: 2266 KCNKDLVTELTLTISDLHEGNDYQFRVSAENAAGVGQPGPPSDTVKA----KLPFDAPGA 2321 Query: 1487 PLKNITTEPNEDIELTCIF------GGVPQPK-VTWYRDGKKLKTAKATYENRXXXXXXX 1539 P K TE N ++T + GG P V ++ + + T E Sbjct: 2322 PGKPQVTEYNIT-KMTITWSPPESDGGSPVTGFVVERKESTSSRWVRVTKETVTETTLIV 2380 Query: 1540 XXXXXXXXY--KCIAFNDHGEVETSCVVGIQQKPV-----ITISNEDIKQKHKVGDE--W 1590 Y + IA N G S +Q+ + ++ K E W Sbjct: 2381 TGLTEGSEYQFRVIAENPAGPGPASEPSDLQKAKLPFDAPSAPGKPEVTSADKTQMELTW 2440 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 V G P I K N + + TT E T+ I K L ++ + A N Sbjct: 2441 AVPDSDGGSPITGYIIQKKENTGKWTQSLKTTTTETTATI--KSLIEKKEYEFRVAAVNL 2498 Query: 1651 AGT------SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 AGT S ++ YD P P P I+ E+ S+TI W PP DGG +T Y +E Sbjct: 2499 AGTGPFSEPSDYQIAKAPYDVPGPPGKPTIL-EVDSTSMTITWTPPETDGGSPVTGYVVE 2557 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTA 1763 K + ++RW KV + + Y I L E +Y FRV A+N G + E S+ K Sbjct: 2558 KRDRVSSRWTKVKETSIEEVVYTIIDLKEGNDYQFRVSAENKAGVGKPSEPSDQRRAKPP 2617 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXX--- 1819 DVP +D + +TW P +GG+ I+ Y VE + K+W Sbjct: 2618 YDVPGPPGIPDISD-VDKNRMTLTWTPPTDDGGAKILGYIVEKCDADRKRWTKAHKEDLV 2676 Query: 1820 XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 + L+ T Y FR+ A N G + P P + Sbjct: 2677 TELTLTVYDLTEGTNYMFRVSAENAAGVGESSLATQPKKAKPPYDEPGPPPPPTPTHVDR 2736 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 S+ L W+ P+ +GGS +T YI+E + WTK+ + + E FR Sbjct: 2737 TSIHLTWSPPDDDGGSEVTGYILEKRDKARNKWTKVNKEPIPEISFTVTGLTEDAIYDFR 2796 Query: 1940 ISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 +SA N G P+ S +++ + VP P+ P+ + +++ + W P +GGA + Sbjct: 2797 VSAVNKAGEGPPSLPSDTLKAKLPFDVPGAPSTPVPSDITETSVHL-EWSPPSNNGGAEI 2855 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 Y + +D + W + G+ +T+ ++DL E + Y R+ A N G P ++ +P Sbjct: 2856 TEYIVEQKDRFSSRWTKAGETPGDTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKP 2915 Query: 2059 FKVIP 2063 F P Sbjct: 2916 FVAKP 2920 Score = 219 bits (535), Expect = 7e-55 Identities = 175/701 (24%), Positives = 284/701 (40%), Gaps = 47/701 (6%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436 D P PGKP ++ +S+ + W P + G S I Y VE ++ +T W I++T Sbjct: 2923 DVPDAPGKPAPSDLSPTSVTLTWTPPPSDGGSPITGYTVEMKDKFSTRWTKATRELISET 2982 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + +LK Y+FR A N+ S S Q+PT++ + T Sbjct: 2983 TVVLPDLKEKEEYQFRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRESPTSAT 3042 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCI 1551 GG ++T Y KK K + E ++ Sbjct: 3043 VKWSPPKSDGG---SEITGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVS 3099 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKN 1609 A N G + S V + KP ++ + W V ++ G + Y Sbjct: 3100 AVNKAGTGKPSQVATLSAKPPGAPDAPEVSDIDRTSATVIWTVPSLDGG---STITGYTI 3156 Query: 1610 GNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV 1662 + + + K K + +++ +L + ++ + A N G S T K Sbjct: 3157 ERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQYEFRVIAENKVGPGEPSNPSARFTAKA 3216 Query: 1663 -YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 +D+P P + +I+ S T+ W PP DGG + Y +E + ++RW KV Sbjct: 3217 PFDEPEAPYS-LAASDITPTSATLSWLPPDSDGGSPILGYTLETKDRFSSRWTKVNKGLL 3275 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 ++ + L EN EY++RVIA+N G S+ + K + P Sbjct: 3276 QETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKDTTPT 3335 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFR 1838 +V ITW +GGSPI Y VE+K+ +W +++L N YQFR Sbjct: 3336 STV-ITWREPSFDGGSPITGYTVEMKEPYSTRWTPANKEPIEETTFLVKRLKENENYQFR 3394 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 + A N G P K PP+ P V + SV L W+ P S+GGS +T Sbjct: 3395 VVAHNLAGPGKP----------KAPKPPTPPE---VKRLSPTSVQLNWSAPTSDGGSEVT 3441 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 YI+E K G+ WT + + ++ +KE +++ FR+SA N G P+E + Sbjct: 3442 AYIVEKKDKSGR-WTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIA 3500 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 A PS P+ P E+ + + +W P+ DGG+ + GY + R+ + W+ V + Sbjct: 3501 ----AKPPSAPSKP-EVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNR 3555 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 V + DL E + Y R+ A N G E ++ F Sbjct: 3556 KPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASF 3596 Score = 210 bits (513), Expect = 3e-52 Identities = 191/764 (25%), Positives = 308/764 (40%), Gaps = 43/764 (5%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-P-SPPGKPNILEIDSSSIN 1398 K + + + ++++ EN G ++ K P P ++ I +S Sbjct: 4350 KDTDYKVMDLTKNEKYYFRVKAENKAGQGKPSLDTKATAKYPFDAPTIDDVSRISETSAK 4409 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAV 1456 I W P N G + I Y++E ++ +W V T TS ++NL+ FR AV Sbjct: 4410 IKWTPPSNDGGAEISGYIIEKKDRLAVKWSPVIEDTLDNTSFTVKNLREGEDVEFRVSAV 4469 Query: 1457 NEVDISDASE-TTEYYKVIKETKI-QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 N+ S T K + ++ ++K +T P E + + G + + + Sbjct: 4470 NKAGTGKPSSIATLAAKPPGPPGVPEASNIDKISATLTWTPPESDGGSKVTGYIVEKRER 4529 Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 + +K +A ++ ++ A N G E S V KP Sbjct: 4530 GL--DRWMKVNRAPVKD-VTLKVLDLTEKKHYEFRVTAENKAGLGEPSDSVSFIAKPPYD 4586 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK------LE-NDKEYNITTKEKT 1627 + D +A + PP Y +G +E D+ + TK K Sbjct: 4587 VPGAP--STPVASDISPTSATLSWSPP-----YSDGGSPITSYTIEMKDRFSSRWTKAKD 4639 Query: 1628 SV----IRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV-YDKPSKPEGPVIMREI 1678 V ++ LK ++ ++ + A N AG + +V VT K +D P P P + R Sbjct: 4640 MVTEETFQLNSLKENNEYQFRVIAENKAGPGEPSPTVNVTAKYEFDTPQAPAEPDV-RRT 4698 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 S SV + W P DGG ++ Y IEK + W +V D ++ ++ L E+ + Sbjct: 4699 SPTSVELSWVKPKSDGGSKIKGYIIEK-KVKGEPWTQVTTDTVDGTSFTVRGLPEDEDVE 4757 Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 FR+ A N G + I K P +D SV +TW P + +GGS Sbjct: 4758 FRISAVNKAGAGSPSNTVVIAFK-----PPGPPGTPEVSDVDKTSVTLTWTPPKLDGGSK 4812 Query: 1799 IIDYKVEIKQEGK-KWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 +I Y VE +++G+ +W I L Y+FR+ A N++G P + + Sbjct: 4813 VIGYIVEKREKGRDRWVRINRSPVREVTMSITDLVEKNEYEFRVIAENKVGPGEPSSPSE 4872 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 +I PS P++ ++ T SVTL W+ P SNGGSPI Y IE K WT + Sbjct: 4873 RIVAKAPYEVPSPPKSLKATDLTPISVTLNWSAPLSNGGSPIVGYTIEMKDKFSTRWTNV 4932 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + + N+KEK++ FR+ A N G P+E SV + P P+ P I Sbjct: 4933 SEHMVTTLSLNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFPFNAPEAPSPP-SI 4991 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + V +W P DGG + GY I +D W V K ++ F I+ L E Sbjct: 4992 ERISPTSVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIIDDTNFTIKGLKEGE 5051 Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 R+ A N+ G +P ++ + PG +QT V Sbjct: 5052 EAEFRVVAVNKAGSGKPSQTTVLAALPPGPPESPSISDVKQTSV 5095 Score = 209 bits (510), Expect = 7e-52 Identities = 181/746 (24%), Positives = 298/746 (39%), Gaps = 46/746 (6%) Query: 1347 IKKVENTDAGIYKLRLENNCG---HADVEMNVTI---LDKPSPPGKPNILEIDSSSINIC 1400 + + D+ +++ EN G +D VT +P+ P +P I + + S + Sbjct: 6533 VMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQISNVTADSATLT 6592 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W P + G S+I Y +E ++ + W V + +T T+ ++ L Y+FR A N+ Sbjct: 6593 WSPPRDDGGSSITGYFIEKKDKFSPRWTRVNHDAVTDTKFTVPALVPGEEYQFRVVAQNK 6652 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-- 1516 S SE TE +++ + P + TE + T F ++T Y Sbjct: 6653 AGASKPSEPTE-STLVRSPFNEPGAPGAPETSNVTETTLTLTWTPPFSD-GGSRITGYYV 6710 Query: 1517 --RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQQKPV 1572 +D L+ + +E+ Y + +A ND G + S PV Sbjct: 6711 EKKDRMSLRWSPVNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRSKPSA----PSYPV 6766 Query: 1573 ITISNEDIKQ---KHKVGDEWLVTAVIEGIPPPE------VIWYKNGNKLENDKEYNITT 1623 S D+ + D + PP + + + + + I+ Sbjct: 6767 KAKSPFDLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISR 6826 Query: 1624 KEKT-SVIRIKELKRSHSSKYTIEASNTAGTSSV-EVT-----LKVYDKPSKPEGPVIMR 1676 + T + + LK + ++ + A N G E T + Y+ PS P+ + Sbjct: 6827 FDFTETTFSVTGLKDGNDYEFRVAAKNKIGIGKFSEPTRPTKAKEPYESPSTPD----VS 6882 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 I+ ES+T+ W P DGG +T Y IEK EP + W V + + L + E Sbjct: 6883 NITGESMTLNWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAE 6942 Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y FRVIA+N G + + P K P + ++ I+W P +G Sbjct: 6943 YEFRVIAENKAGLGRPSQVTHPFTAKPPYTTPG-IPDQPEVEDVTATTITISWSPPSYDG 7001 Query: 1796 GSPIIDYKVEIKQEG-KKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 GS I Y +E K + +W K +L + YQFR+ A N+ G Sbjct: 7002 GSKITGYTIESKSDATMRWVKIESTVPDTTYTAARLKELSEYQFRVAAINKAGRGDFSKP 7061 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 +T PP P V T S L W+ P +GGSPIT Y+I+ K W Sbjct: 7062 SRPVTCKPPYDPPPPPDAPDVYNITPTSAALTWSTPRQDGGSPITGYVIDKKDKYSTRWV 7121 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAP 1972 K V + I+ ++ ++ FR+SA N GV P+ + + VP P+ P Sbjct: 7122 KADEVPAGTTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPDAPSPP 7181 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 + S++ + SW P DGG+ + GY + R+ W+ V + + F + DLS Sbjct: 7182 SVSDITPSSMTL-SWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLS 7240 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEP 2058 E+ Y R+ A N G+ +P E P Sbjct: 7241 EDRKYEFRVSAENAAGVGKPSEVSLP 7266 Score = 205 bits (501), Expect = 9e-51 Identities = 122/422 (28%), Positives = 200/422 (47%), Gaps = 16/422 (3%) Query: 1642 KYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 ++ + A N AG + SV +T ++ P PE + S +SV + W PP + GG Sbjct: 5348 EFHVIAINKAGEGKPSPSVSLTFRLPGPPGTPE----VYNPSDKSVDLRWTPPTEQGGTR 5403 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756 + Y IEK E + W+++ Y + L NC + FRV A+N G + SE Sbjct: 5404 IIGYFIEKCEVGKDNWVRINRSSIREANYVVGDLTLNCRFKFRVCAENRAGVGPPSDYSE 5463 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKX 1815 ++IK DVP + N+S+ I+W P +GGS + +Y +E K+ KW Sbjct: 5464 SVLIKLPYDVPESPDTPKISD-VTNDSMVISWQPPYSDGGSKVTEYIIEKKEPYSSKWVP 5522 Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 +I L N Y+FR+ A N+ G S PSQP + ++ Sbjct: 5523 VTKTRDLSYKITGLKENGDYEFRVAAVNKAGASEFSVPTPSTKAKLPYDVPSQPHSLKIA 5582 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + + S+TL+W+EP+S+GG ++ YIIE K WT + S + + +K+ + Sbjct: 5583 DVSPTSLTLEWSEPDSDGGDNVSGYIIEKKDRFSPRWTPVNQTAISDTKFKVTGLKDGQD 5642 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 FR+ A+N G S P+ + ++ P P+ P +I+ V N V SW PE DGG Sbjct: 5643 CEFRVVAKNKAGASQPSSVATFSIKP----PDAPSRP-DIKKVTENSVTLSWSPPESDGG 5697 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 +P+ Y + R+ + W++ + + F ++DL+ H Y R+ A N+ GL E+ Sbjct: 5698 SPVTSYIVERREPDRDYWVKATRYPITDTTFTVQDLTPKHKYEFRVIAENKAGLGGASEA 5757 Query: 2056 DE 2057 + Sbjct: 5758 SK 5759 Score = 205 bits (500), Expect = 1e-50 Identities = 194/736 (26%), Positives = 307/736 (41%), Gaps = 49/736 (6%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSS 1395 + S + +E + +Y++ EN G + + K P PG + + Sbjct: 3276 QETSFKVTNLEENNEYVYRVIAENKAGPSKPSNECKFIAKHQFETPEAPGNVVAKDTTPT 3335 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453 S I W EP G S I Y VE +E +T W I +T ++ LK N +Y+FR Sbjct: 3336 STVITWREPSFDGGSPITGYTVEMKEPYSTRWTPANKEPIEETTFLVKRLKENENYQFRV 3395 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 A N ++ + K K +P K L + + N + GG +V Sbjct: 3396 VAHN---LAGPGKP-------KAPKPPTPPEVKRLSPTSVQLNWSAPTS--DGG---SEV 3440 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXX-----XXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 T Y KK K+ + T ++ A N G + S V I Sbjct: 3441 TAYIVEKKDKSGRWTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIA 3500 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT- 1627 KP S ++ K TA + + D+ + K T Sbjct: 3501 AKPPSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTE 3560 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKPSKPEGPVIMREISRE 1681 + +++ +L ++ ++ + A N AG +S T K +D+PS P P I+ Sbjct: 3561 TTMKVPDLVEKNNYEFRVIAENRAGPGEASDASASFTAKAPFDEPSAPGVPK-ASNITPT 3619 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFR 1740 SVT+ W P DGG +T+Y +E + ++++ V D D+ T+ ++ L EN EY FR Sbjct: 3620 SVTLSWTAPDSDGGSPITEYILESKDKYSSKFSPVTRDTVTDL-TFTVKNLKENGEYQFR 3678 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 VIAQN G SE +V K +VP + S+ + W P +GGS I Sbjct: 3679 VIAQNKAGPSEPSRETKVVAKYEFEVPQ-APSAPEVRRLSPTSIQLDWTPPFADGGSDIT 3737 Query: 1801 DYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 Y +E K++ +W ++ L + +FRI A N+ G S P ++T Sbjct: 3738 GYIIEKKEKSGRWTPVSSDSVDGTTFTVKGLPDDEDVEFRISAVNKAGQSKP----SQVT 3793 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVT 1917 + T PP P VS+ S T+ W S+GGS IT YI+E K KG+ W + Sbjct: 3794 V-LTAKPPGAPGRPEVSDINKTSATVTWKPSSSDGGSTITGYIVE-KREKGRDRWVPVNR 3851 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIR 1976 + + ++ EK + FR+ AEN +G P+E + + K VP+ P AP Sbjct: 3852 KPINAVTMKVTDLTEKTDYEFRVIAENRIGQGQPSEPSAKFIAKSPFDVPTAPGAPKASD 3911 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 + +++ +T W P DGG+P+ + I +D T + + K L F + L + Sbjct: 3912 ITPTSLTLT-WTPPTDDGGSPITNFIIEWKDKFSTRFTILKKDLFVELTFKVTGLKDKTE 3970 Query: 2037 YMIRIYARNEIGLSEP 2052 Y RI A N+ G SEP Sbjct: 3971 YTFRIIAENKEGQSEP 3986 Score = 205 bits (500), Expect = 1e-50 Identities = 128/444 (28%), Positives = 205/444 (46%), Gaps = 18/444 (4%) Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEV-----TLKV-YDKPSKPEGPVIMREISR 1680 T+ IK L+ + ++ + A N AG T K Y P P P + +I+ Sbjct: 7130 TTDFTIKGLQAGNDYEFRVSAVNAAGVGKPSAPCERFTAKAQYGVPDAPSPPSVS-DITP 7188 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 S+T+ W+PP DGG +T Y +EK E RW+ V T+ + L+E+ +Y FR Sbjct: 7189 SSMTLSWEPPASDGGSTVTGYIVEKRESPVGRWVPVNRAPIKETTFKVNDLSEDRKYEFR 7248 Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A+N G + E S P V K+ D PS +D+ + + W +GGSPI Sbjct: 7249 VSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATN-VDSTELVLEWTAPVADGGSPI 7307 Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 +Y +E + + G +W ++ L N YQFR+ A N++G P + + Sbjct: 7308 TNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQFRVIAENKVGLGRPSDNTES 7367 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 I P P + V+ +T+ S +L+W+ P S+GGSP+T Y +E K WT++ Sbjct: 7368 IVAKPPYDTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVN 7427 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE-- 1974 V + + ++KE + FR+ AEN G+ ++S + K P+APLE Sbjct: 7428 RVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPV--DAPSAPLEPT 7485 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 I + ++ +W P DGG+ + GY + +D W + + K I L E Sbjct: 7486 IASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPIERCTDTNCK--ISGLKEG 7543 Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058 + Y R+ A N+ G S P +P Sbjct: 7544 NEYQFRVVATNKAGQSAPSNPSQP 7567 Score = 204 bits (497), Expect = 3e-50 Identities = 174/691 (25%), Positives = 276/691 (39%), Gaps = 30/691 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 PSPPG+P I I + S+ + W P + G S + Y VE + +T W+ V + I T+ Sbjct: 7776 PSPPGEPTISNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTRWVPVNSHPIKDTKM 7835 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 I +L SY+FR A N S + T+ + K+ + K + Sbjct: 7836 DIHDLPATGSYQFRIVACNAAGTSKPTSPTDSIGMAVAPKLDT---YKYHDTMVVRVGAT 7892 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFN 1554 L F P+P V W +DG L+ + T + +K N Sbjct: 7893 FNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSN 7952 Query: 1555 DHGEVETSCVVGI---QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 G + V + ++P + +DI + W A G P I + Sbjct: 7953 TAGSDAITIRVQVLDRPEQPRGPLVAKDIGST-DLFLSWKEPADTGGSPITHYIIER--R 8009 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDK 1665 + + +TT+ + +R+ L+ S + + A N G S + T+K+ YD Sbjct: 8010 EEDRTSWTRLTTRALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDV 8069 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P P P++ ++ +SVT+EW P DGG ++ Y IEK E +N W KV V V + Sbjct: 8070 PEAPSKPLV-TNVTSDSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTS 8128 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + I +L EY FRV A+N G A S PI + +P Sbjct: 8129 HRIPRLMRGEEYEFRVSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEPIMAKVGES 8188 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 + P +P + + + + + I ++ R Y N Sbjct: 8189 FRIEVP-YTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGGR-YTINL 8246 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 T+ + D ++ + PP P VSEST VTL W+ P +GGS I Y+++ Sbjct: 8247 KNTAGAESLDVEVRVFDRPGPPRGPLEMSNVSEST---VTLSWSPPSDDGGSRIFTYVVQ 8303 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 + W + + + +KE + FR+ AEN G S P E QS+ + Sbjct: 8304 KRGEIETKWKHVNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITPQGQY 8363 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 VP PP+AP ++G ++ + W P DGGAP+ GY + +R T W++ Sbjct: 8364 NVPDPPSAPKVTNIIGDSVTV-GWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLTPTPD 8422 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + F L Y R+ A N G P E Sbjct: 8423 MTFRASRLIRGTEYEFRVCAVNRAGTGRPGE 8453 Score = 200 bits (487), Expect = 4e-49 Identities = 132/440 (30%), Positives = 201/440 (45%), Gaps = 15/440 (3%) Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPSKPEGPVIMREISRESV 1683 E TS +K LK ++ + A N AGT EVT+ PS P P + +I + S Sbjct: 3463 EDTS-FTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIAAKPPSAPSKPEVT-DIQKTSA 3520 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 + W P +DGG ++T Y +EK E ++W++V T + L E Y FRVIA Sbjct: 3521 VVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTETTMKVPDLVEKNNYEFRVIA 3580 Query: 1744 QNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 +N G EA + S K D PS I SV ++W + +GGSPI +Y Sbjct: 3581 ENRAGPGEASDASASFTAKAPFDEPS-APGVPKASNITPTSVTLSWTAPDSDGGSPITEY 3639 Query: 1803 KVEIKQE-GKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 +E K + K+ ++ L N YQFR+ A+N+ G S P + + K+ Sbjct: 3640 ILESKDKYSSKFSPVTRDTVTDLTFTVKNLKENGEYQFRVIAQNKAGPSEP-SRETKVVA 3698 Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919 P P V + S+ L WT P ++GGS IT YIIE K G+ WT + + Sbjct: 3699 KYEFEVPQAPSAPEVRRLSPTSIQLDWTPPFADGGSDITGYIIEKKEKSGR-WTPVSSDS 3757 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 ++ + + +++ FRISA N G S P++ + A P P P E+ + Sbjct: 3758 VDGTTFTVKGLPDDEDVEFRISAVNKAGQSKPSQVTVLT----AKPPGAPGRP-EVSDIN 3812 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 +W DGG+ + GY + R+ + W+ V + +N + + DL+E Y Sbjct: 3813 KTSATVTWKPSSSDGGSTITGYIVEKREKGRDRWVPVNRKPINAVTMKVTDLTEKTDYEF 3872 Query: 2040 RIYARNEIGLSEPLESDEPF 2059 R+ A N IG +P E F Sbjct: 3873 RVIAENRIGQGQPSEPSAKF 3892 Score = 199 bits (485), Expect = 8e-49 Identities = 125/430 (29%), Positives = 200/430 (46%), Gaps = 18/430 (4%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEV---TLKV---YDKPSKPEGPVIMREISRESVTI 1685 +++L+ H + + A N AG+ V T K Y P P PVI E++ SV + Sbjct: 6031 VRDLRAGHEYSFRVAAVNKAGSGKPSVPSETFKAQPPYAAPEAPSAPVI-EEVTANSVKL 6089 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQ 1744 W+PP DGG + Y +EK + + RW +V+R ET + + KL E FRV A Sbjct: 6090 SWEPPRLDGGSHIIDYVVEKKDAFSIRW---TEVNRTPETTFTVPKLKEGDAVQFRVTAV 6146 Query: 1745 NPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G + +S + +K VP +D S+ + W + +GGS I +Y Sbjct: 6147 NKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVE-VDAVSITVRWSAPKNDGGSRITNYI 6205 Query: 1804 VEIKQEGKK-WKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 +E+K++ WK Q + N T +FR+ A N+ G P + T Sbjct: 6206 LEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVNKAGEGKPSSVGGPFTTK 6265 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 T T PS P VS + S+T+ WT+ S+GGSPIT Y++E V W + V Sbjct: 6266 ATYTVPSAPGAPDVSNVKATSMTVTWTKSISDGGSPITGYVLEKCDVSTGRWVPVNRVPL 6325 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVG 1979 ++ ++EK E FR+ A N G S P+E + K +P P P +I + Sbjct: 6326 RETSLVVDQLREKSEYCFRVVAHNVAGESKPSEPSKAYIAKPPYGLPDAPAKP-DITNID 6384 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 + + +W P DGG+P++GY I +D W + ++ +++ +R+L+E Sbjct: 6385 AKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRETIHDMQYTLRELTEGGEVEF 6444 Query: 2040 RIYARNEIGL 2049 R+ A N+ G+ Sbjct: 6445 RVAAENKAGV 6454 Score = 198 bits (484), Expect = 1e-48 Identities = 128/440 (29%), Positives = 191/440 (43%), Gaps = 17/440 (3%) Query: 1628 SVIRIKELKRSHSSKYTIEASNTAG-------TSSVEVTLKVYDKPSKPEGPVIMREISR 1680 + ++ LK + ++ + A N G T S+ V YD P PE V + + Sbjct: 7333 TTFKVTGLKPNDEYQFRVIAENKVGLGRPSDNTESI-VAKPPYDTPDAPES-VQVTGTTA 7390 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 S ++EW PP DGG +T Y +E+ + + RW +V V + L E +Y FR Sbjct: 7391 SSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVNRVPVTETNMVVGDLKEGLQYQFR 7450 Query: 1741 VIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A+N G + +S +P VIK +D PS I +S +TW ++GGS + Sbjct: 7451 VCAENRAGIGRSSDSTKPTVIKDPVDAPSAPLEPTIAS-ITADSATLTWIAPSRDGGSAV 7509 Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 Y VE K +W +I L YQFR+ A N+ G S P Sbjct: 7510 TGYIVERKDPYTARWTPIERCTDTNCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKV 7569 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 P P V+E + SVTLKW P S+GGSPIT Y+++ K WT + T Sbjct: 7570 AKSPYDVPEAPSKPQVTEVKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTT 7629 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977 + + +K E FR+ A N G P+E + SV ++ PSPP + Sbjct: 7630 PVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPPV----VTD 7685 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 V W PE DGG+ + GY + ++ W + +F ++DL E Y Sbjct: 7686 FTKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQY 7745 Query: 2038 MIRIYARNEIGLSEPLESDE 2057 R+ A N+ G+ P + E Sbjct: 7746 EFRVMALNKAGIGPPSDGSE 7765 Score = 196 bits (477), Expect = 7e-48 Identities = 130/451 (28%), Positives = 201/451 (44%), Gaps = 19/451 (4%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKV-YDKPSKPEGPV 1673 N + E T +++ L ++ + A N AG S S V K +D PS P P Sbjct: 6724 NFESTEDTK-LKVTGLTEGTEYEFRVVAENDAGRSKPSAPSYPVKAKSPFDLPSAPGTPS 6782 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733 I +IS ++T+ W PP DGG + + +E+ E + RW++++ D T+ + L + Sbjct: 6783 IS-DISSTNMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISRFDFTETTFSVTGLKD 6841 Query: 1734 NCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 +Y FRV A+N +G + E + P K + PS I ES+ + W Sbjct: 6842 GNDYEFRVAAKNKIGIGKFSEPTRPTKAKEPYESPSTPDVSN----ITGESMTLNWTAPR 6897 Query: 1793 KNGGSPIIDYKVEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSL 1849 +GGSPI Y +E ++ G+ W + L Y+FR+ A N+ G Sbjct: 6898 TDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQGAEYEFRVIAENKAGLGR 6957 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 P T T P P V + T+ ++T+ W+ P +GGS IT Y IE K+ Sbjct: 6958 PSQVTHPFTAKPPYTTPGIPDQPEVEDVTATTITISWSPPSYDGGSKITGYTIESKSDAT 7017 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVRLEKHATVPSP 1968 W KI + + +KE E FR++A N G S+ V + P P Sbjct: 7018 MRWVKIESTVPDT-TYTAARLKELSEYQFRVAAINKAGRGDFSKPSRPVTCKPPYDPPPP 7076 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 P AP + ++ +T W TP DGG+P+ GY I +D T W++ +V T F I Sbjct: 7077 PDAPDVYNITPTSAALT-WSTPRQDGGSPITGYVIDKKDKYSTRWVKADEVPAGTTDFTI 7135 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 + L + Y R+ A N G+ +P E F Sbjct: 7136 KGLQAGNDYEFRVSAVNAAGVGKPSAPCERF 7166 Score = 194 bits (474), Expect = 2e-47 Identities = 127/455 (27%), Positives = 212/455 (46%), Gaps = 18/455 (3%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKV-YDKPSKPEGPV 1673 N T KT + L S ++ + A N G S+ +VT K Y +P+ P P Sbjct: 6522 NRTQVLKTG-FNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQKVTAKPPYSQPAAPNEPQ 6580 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLN 1732 I ++ +S T+ W PP DDGG +T Y IEK + + RW +V D D + + + L Sbjct: 6581 ISN-VTADSATLTWSPPRDDGGSSITGYFIEKKDKFSPRWTRVNHDAVTDTK-FTVPALV 6638 Query: 1733 ENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 EY FRV+AQN G S+ E +E ++++ + P + ++ +TW P Sbjct: 6639 PGEEYQFRVVAQNKAGASKPSEPTESTLVRSPFNEPGAPGAPETSN-VTETTLTLTWTPP 6697 Query: 1792 EKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTS 1848 +GGS I Y VE K +W +++ L+ T Y+FR+ A N+ G S Sbjct: 6698 FSDGGSRITGYYVEKKDRMSLRWSPVNFESTEDTKLKVTGLTEGTEYEFRVVAENDAGRS 6757 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 P + PS P +S+ +S ++TL+W PES+GG+ I +I+E + Sbjct: 6758 KPSAPSYPVKAKSPFDLPSAPGTPSISDISSTNMTLRWAPPESDGGTVIITFIVERREQF 6817 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 W +I + + +K+ ++ FR++A+N +G+ S+ R K Sbjct: 6818 STRWVQISRFDFTETTFSVTGLKDGNDYEFRVAAKNKIGIG--KFSEPTRPTKAKEPYES 6875 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 P+ P + G ++ + +W P DGG+P+ GY I R+ ++ W V + + +L + Sbjct: 6876 PSTPDVSNITGESMTL-NWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVV 6934 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 +L + Y R+ A N+ GL P + PF P Sbjct: 6935 PNLRQGAEYEFRVIAENKAGLGRPSQVTHPFTAKP 6969 Score = 193 bits (471), Expect = 4e-47 Identities = 135/453 (29%), Positives = 190/453 (41%), Gaps = 18/453 (3%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTL-----KVYDKPSKPEGPVIMREIS 1679 K + ++ +L ++ + A N AG EV+L YD PS P P S Sbjct: 7230 KETTFKVNDLSEDRKYEFRVSAENAAGVGKPSEVSLPRVAKSPYDAPSAPGRPTATNVDS 7289 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 E V +EW P+ DGG +T Y IE + RW K+ T+ + L N EY F Sbjct: 7290 TELV-LEWTAPVADGGSPITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPNDEYQF 7348 Query: 1740 RVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 RVIA+N VG ++ E IV K D P + S + W P +GGSP Sbjct: 7349 RVIAENKVGLGRPSDNTESIVAKPPYDTPDAPESVQVTGTTAS-SASLEWSPPFSDGGSP 7407 Query: 1799 IIDYKVEIK-QEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 + Y VE K Q +W + L YQFR+ A N G S Sbjct: 7408 VTGYFVERKDQYSARWTRVNRVPVTETNMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTK 7467 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 I + PS P ++ T+ S TL W P +GGS +T YI+E K WT I Sbjct: 7468 PTVIKDPVDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPI 7527 Query: 1916 VTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPL 1973 + +C I +KE +E FR+ A N G S P+ ++ K VP P+ P Sbjct: 7528 ERCTDT---NCKISGLKEGNEYQFRVVATNKAGQSAPSNPSQPKVAKSPYDVPEAPSKP- 7583 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033 ++ V + V W P DGG+P+ GY + ++ W V V F + L++ Sbjct: 7584 QVTEVKATSVTLKWRPPGSDGGSPITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQ 7643 Query: 2034 NHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 Y R+ A N+ G +P E V P G Sbjct: 7644 KSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYG 7676 Score = 190 bits (462), Expect = 5e-46 Identities = 133/464 (28%), Positives = 207/464 (44%), Gaps = 20/464 (4%) Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV- 1662 K + N E+ +TT + + LK + ++ + A N AG + + VT K Sbjct: 4924 KFSTRWTNVSEHMVTTLS----LNVPNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFP 4979 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 ++ P P P I R IS SV + W PP DGG ++T Y IEK + + RW V D Sbjct: 4980 FNAPEAPSPPSIER-ISPTSVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIID 5038 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + I+ L E E FRV+A N G + ++ + AL P + Sbjct: 5039 DTNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQT---TVLAAL--PPGPPESPSISDVKQT 5093 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYA 1841 SV ++W P E +GGS II Y VE K G+ K + L + Y+FR+ A Sbjct: 5094 SVTLSWTPPESDGGSKIIGYIVEKKDMGRWVKVNRSPVRETTMVVTDLVEKSEYEFRVMA 5153 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N++G P ++ P +P V++ +T+KW+ P S+GGS IT YI Sbjct: 5154 ENKVGVGEPSAPSSRVVAKLPFDVPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYI 5213 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLE 1960 +E K W+++ + + + E + FRI AEN G S P+E S++ + Sbjct: 5214 VEMKEPYSSRWSQVTKTTDFTFK--VTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFTAK 5271 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 VP P P E+ + + W P DGG+P+LGY + +D T W V Sbjct: 5272 LPFGVPGAPDTP-ELTDIKDFSLTVKWLAPTSDGGSPILGYFVEQKDQFSTRWQRVKSSP 5330 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064 + LKF + ++ ++ + A N+ G +P S +PG Sbjct: 5331 ILDLKFTVTNVQDDAECEFHVIAINKAGEGKPSPSVSLTFRLPG 5374 Score = 186 bits (452), Expect = 8e-45 Identities = 132/444 (29%), Positives = 201/444 (45%), Gaps = 17/444 (3%) Query: 1632 IKELKRSHSSKYTIEASNTAGT-----SSVEVTLKV-YDKPSKPEGPVIMREISRESVTI 1685 + +LK + ++ + A N AG SSV VTLK + P P P + E+ S+T+ Sbjct: 6130 VPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAV-EVDAVSITV 6188 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 W P +DGG +T Y +E E ++ W +V+ + TY + L EN FRVIA N Sbjct: 6189 RWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIAVN 6248 Query: 1746 PVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 G + P K VPS + S+ +TW S +GGSPI Y + Sbjct: 6249 KAGEGKPSSVGGPFTTKATYTVPSAPGAPDVSN-VKATSMTVTWTKSISDGGSPITGYVL 6307 Query: 1805 E-IKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 E +W + +L + Y FR+ A N G S P + K I K Sbjct: 6308 EKCDVSTGRWVPVNRVPLRETSLVVDQLREKSEYCFRVVAHNVAGESKP-SEPSKAYIAK 6366 Query: 1862 T-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 P P ++ ++ +TL W+ P S+GGSPI Y IE K WT+ Sbjct: 6367 PPYGLPDAPAKPDITNIDAKQITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRETI 6426 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVG 1979 ++ + + E E+ FR++AEN GV +E+ + K VPS P P + G Sbjct: 6427 HDMQYTLRELTEGGEVEFRVAAENKAGVGPFSETTGTVIAKSPFDVPSAPGTPKISDITG 6486 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 +++V+T W P DGG + + I +RD W V + V FN+ +LSE +Y Sbjct: 6487 TSLVLT-WTPPSSDGGTEITNFIIELRD-RYGRWTRVNRTQVLKTGFNVMNLSEGDSYEF 6544 Query: 2040 RIYARNEIGLSEPLESDEPFKVIP 2063 R+ A N++G+ +P +S + P Sbjct: 6545 RVTAENKMGVGKPSDSTQKVTAKP 6568 Score = 184 bits (448), Expect = 2e-44 Identities = 139/464 (29%), Positives = 204/464 (43%), Gaps = 26/464 (5%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV------YDKPSKPEGPVIMR 1676 T T I +K+LK + ++ + A N AG S K YD P P P Sbjct: 2876 TPGDTVTITLKDLKEGNEYQFRVIAVNPAGPGSPSDACKPFVAKPPYDVPDAPGKPA-PS 2934 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 ++S SVT+ W PP DGG +T Y +E + + RW K T + L E E Sbjct: 2935 DLSPTSVTLTWTPPPSDGGSPITGYTVEMKDKFSTRWTKATRELISETTVVLPDLKEKEE 2994 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y FRVIA+N G S+ + K + P S + W P + +GG Sbjct: 2995 YQFRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRE-SPTSATVKWSPPKSDGG 3053 Query: 1797 SPIIDYKVEIKQE-GKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 S I Y +E K++ +W + ++ L +FR+ A N+ GT P Sbjct: 3054 SEITGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKP---S 3110 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 T+ + PP P VS+ S T+ WT P +GGS IT Y IE + WT+ Sbjct: 3111 QVATL--SAKPPGAPDAPEVSDIDRTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTR 3168 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + + ++ EK++ FR+ AEN VG P+ + S R A P AP Sbjct: 3169 VNKSLVKDTTLKVNDLTEKNQYEFRVIAENKVGPGEPS-NPSARFTAKAPF-DEPEAPYS 3226 Query: 1975 IRMVGSNIVMT----SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 + S+I T SW P+ DGG+P+LGY + +D + W +V K + F + + Sbjct: 3227 --LAASDITPTSATLSWLPPDSDGGSPILGYTLETKDRFSSRWTKVNKGLLQETSFKVTN 3284 Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074 L EN+ Y+ R+ A N+ G S+P S+E K I E PG Sbjct: 3285 LEENNEYVYRVIAENKAGPSKP--SNE-CKFIAKHQFETPEAPG 3325 Score = 181 bits (440), Expect = 2e-43 Identities = 197/875 (22%), Positives = 344/875 (39%), Gaps = 68/875 (7%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 V W K S ++ + + + + + + I+ C +D+ + LD +T + + Sbjct: 7907 VKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFK---LDVSNTAGS--DAITI 7961 Query: 1287 PPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPND-------EWIVNSKIIKKCKHTKPSI 1338 +++D + R D+ + ++ +P D +I+ + + T+ + Sbjct: 7962 RVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTT 8021 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEI 1392 + ++ + ++ + ++++ N G ++ +E TI D P P KP + + Sbjct: 8022 RALDTTVRVTSLQEGASYVFRVFAVNKIGDSEPLETKETIKLKKKYDVPEAPSKPLVTNV 8081 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450 S S+ + W P++ G + I Y++E +E + W V ++ TS I L Y Sbjct: 8082 TSDSVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRIPRLMRGEEYE 8141 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 FR A N AS + + ++T + + + I + E + + G+P Sbjct: 8142 FRVSAENRAGPGPASTPSAPIRA-EDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPT 8200 Query: 1511 PKVTWYRDGKKLKTA---KATYENRXXX-XXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 P VTW DG+ LK + + NR Y N G V Sbjct: 8201 PAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGGRYTINLKNTAGAESLDVEVR 8260 Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNI 1621 + +P + V + T + PP + + Y + E + ++ Sbjct: 8261 VFDRPG---PPRGPLEMSNVSES---TVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKH 8314 Query: 1622 TTKEKTSVIRIK--ELKRSHSSKYTIEASNTAGTS----SVEVTLK-VYDKPSKPEGPVI 1674 K+ + K LK + ++ + A N G S +T + Y+ P P P + Sbjct: 8315 VNKDYIIDLTYKVTGLKENKKYQFRVLAENQYGQSKPLEGQSITPQGQYNVPDPPSAPKV 8374 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 I +SVT+ W PP +DGG +T Y +E + + RWIK T+ +L Sbjct: 8375 TNIIG-DSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLTPTPDMTFRASRLIRG 8433 Query: 1735 CEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 EY FRV A N G E S ++++ P I + + F + Sbjct: 8434 TEYEFRVCAVNRAGTGRPGEPSNTVMVEDPAVKPKFNLDARFEKVITIRAGHT--FRID- 8490 Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPY 1851 I YK W RI S N TT R R + G + Sbjct: 8491 ------IPYKA-TPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIR 8543 Query: 1852 TS----DDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 S +D +T+ + PS P+ + + S VTL W+ P +GGSPIT Y++E + Sbjct: 8544 ASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEKR 8603 Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965 SWT + + + + E E FR+ AEN +GVS P ES+ + + V Sbjct: 8604 EGGYGSWTNVSSKIPDT-TFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDYDV 8662 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD--VTKTMWMEVGKVDVNT 2023 P P +++ + S+ V +W P+ DGGAP+ GY + R+ + W V Sbjct: 8663 PDQP-GKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPVMD 8721 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + LSE Y R+ A N+ G+S P + P Sbjct: 8722 TTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAP 8756 Score = 180 bits (438), Expect = 4e-43 Identities = 162/702 (23%), Positives = 276/702 (39%), Gaps = 37/702 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 P PP P + I S+ + W P N G + + YVVE ++ + WI +T T Sbjct: 8366 PDPPSAPKVTNIIGDSVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKA-TLTPTPDMT 8424 Query: 1441 ---QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 L + Y FR AVN E + V+ E P K IT Sbjct: 8425 FRASRLIRGTEYEFRVCAVNRAGTGRPGEPSN--TVMVEDPAVKPKFNLDARFEKVITIR 8482 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENR---XXXXXXXXXXXXXXXYKC 1550 + + P P V+W ++G + K+ + T ++ Y Sbjct: 8483 AGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVI 8542 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608 A N GE + V + P + + ++V W G P + K Sbjct: 8543 RASNKAGEDTVTVTVNVVDSPSPPQGPLALVKLGSNEVTLSWSRPRDDGGSPITGYVLEK 8602 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----Y 1663 + N+++K + R+ +L ++ + A N G S + ++ Y Sbjct: 8603 REGGYGSWT--NVSSKIPDTTFRVTKLTEDREYQFRVRAENNLGVSEPLESERIIPKGDY 8660 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WIKVADVDR 1721 D P +P G + + I +SV++ W P DGG +T Y +EK E W + + Sbjct: 8661 DVPDQP-GKIKVDTIQSDSVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPV 8719 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780 T + +L+E EY FRV A N G S A + P++++ P I Sbjct: 8720 MDTTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVIT 8779 Query: 1781 NESVYITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 + + +G +P + + ++ KQ +G++ K + + + Sbjct: 8780 VRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTY 8839 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSP 1896 I N+ GT T+ ++ + L PS P + V+ T SVTL W P+ +GG+ Sbjct: 8840 TIKISNKAGTD---TATIRVAV---LDKPSAPEGPIKVTSITCDSVTLAWEPPKDDGGAD 8893 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 IT YI+E + WT++ + S + + +K+ +FR+ A + G S P E++ Sbjct: 8894 ITGYILERREPDQFRWTRVTSTLSSPR-YAVTGLKDGRSYLFRVRAVSKYGESEPLETED 8952 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 L K A P + V + + SW P DGGA + Y + I++ T W+ Sbjct: 8953 AILIKSAFEKPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKETRGTRWLRA 9012 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + + F + LS+ Y R+ A NE GL ++ P Sbjct: 9013 TRKQLKSPNFRVTGLSKGREYEFRVAAENEAGLGAFSKTSAP 9054 Score = 178 bits (434), Expect = 1e-42 Identities = 179/700 (25%), Positives = 273/700 (39%), Gaps = 52/700 (7%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 +D PS P +P I I + S + W P G S + Y+VE ++ T W ++ T T Sbjct: 7475 VDAPSAPLEPTIASITADSATLTWIAPSRDGGSAVTGYIVERKDPYTARWTPIERCTDTN 7534 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 I LK + Y+FR A N+ S S ++ KV K KP +T Sbjct: 7535 CKISGLKEGNEYQFRVVATNKAGQSAPSNPSQ-PKVAKSPYDVPEAPSKP--QVTEVKAT 7591 Query: 1498 DIELTC----IFGGVPQPKVTWYRDGKKLKTA------KATYENRXXXXXXXXXXXXXXX 1547 + L GG P +T Y KK + A T Sbjct: 7592 SVTLKWRPPGSDGGSP---ITGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQKSEYE 7648 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW- 1606 ++ +A N G + S + + + + V ++ T+V PPE Sbjct: 7649 FRVVAANKKGFGQPS-----EPTNSVLVKPPYGRPSPPVVTDFTKTSVTLQWNPPESDGG 7703 Query: 1607 -YKNGNKLENDKEYNITTKEKTSVIRIK------ELKRSHSSKYTIEASNTAGT------ 1653 + G LE + Y++ TS +K +LK ++ + A N AG Sbjct: 7704 SHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYEFRVMALNKAGIGPPSDG 7763 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 S + + PS P P I I+ +SVT+ W PP DGG +T Y +E+ + + RW Sbjct: 7764 SELATAKSKFGVPSPPGEPTI-SNITAKSVTLNWTPPSSDGGSPVTGYTVERADRFSTRW 7822 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 + V I L Y FR++A N G S+ S I A+ P Sbjct: 7823 VPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKP-TSPTDSIGMAV-APKLDTYK 7880 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSI 1831 + K P + + + Q + K I+ Sbjct: 7881 YHDTMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVR 7940 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEP 1889 F++ N G+ D ITI + L P QPR V + S + L W EP Sbjct: 7941 EDEGSFKLDVSNTAGS-------DAITIRVQVLDRPEQPRGPLVAKDIGSTDLFLSWKEP 7993 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 GGSPIT+YIIE + SWT++ T + +++E +FR+ A N +G S Sbjct: 7994 ADTGGSPITHYIIERREEDRTSWTRLTTRALDTTVR-VTSLQEGASYVFRVFAVNKIGDS 8052 Query: 1950 LPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 P E+ ++++L+K VP P+ PL + V S+ V W +P+ DGGAP+ GY I ++ Sbjct: 8053 EPLETKETIKLKKKYDVPEAPSKPL-VTNVTSDSVTLEWHSPKSDGGAPISGYIIEKKET 8111 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + W +V V I L Y R+ A N G Sbjct: 8112 SSNYWSKVTTVSSGVTSHRIPRLMRGEEYEFRVSAENRAG 8151 Score = 165 bits (400), Expect = 2e-38 Identities = 125/447 (27%), Positives = 195/447 (43%), Gaps = 18/447 (4%) Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKP--SKPEGPVIMREI 1678 TT ++ + L + ++ + A+N G E T V KP +P PV+ + Sbjct: 7628 TTPVGDTIFTVTGLTQKSEYEFRVVAANKKGFGQPSEPTNSVLVKPPYGRPSPPVVT-DF 7686 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 ++ SVT++W PP DGG +T Y +EK E + RW + ++ L E +Y Sbjct: 7687 TKTSVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEGAQYE 7746 Query: 1739 FRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV+A N G + SE K+ VPS I +SV + W P +GGS Sbjct: 7747 FRVMALNKAGIGPPSDGSELATAKSKFGVPSPPGEPTISN-ITAKSVTLNWTPPSSDGGS 7805 Query: 1798 PIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 P+ Y VE +W + I L +YQFRI A N GTS P + Sbjct: 7806 PVTGYTVERADRFSTRWVPVNSHPIKDTKMDIHDLPATGSYQFRIVACNAAGTSKPTSPT 7865 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 D +IG + P + + T P P + + T++ S K Sbjct: 7866 D--SIGMAVAPKLDTYKYHDTMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIK 7923 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 I T I+N +DE F++ NT G +++ ++R++ P P PL Sbjct: 7924 IDTTDRDTIV-TIKNCVREDEGSFKLDVSNTAG----SDAITIRVQV-LDRPEQPRGPLV 7977 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 + +GS + SW P GG+P+ Y I R+ +T W + ++T + L E Sbjct: 7978 AKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLTTRALDTT-VRVTSLQEG 8036 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKV 2061 +Y+ R++A N+IG SEPLE+ E K+ Sbjct: 8037 ASYVFRVFAVNKIGDSEPLETKETIKL 8063 Score = 163 bits (395), Expect = 6e-38 Identities = 107/441 (24%), Positives = 193/441 (43%), Gaps = 18/441 (4%) Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTIL-----DKPSPPGK 1386 H +P S + T KK+++ + ++ EN G + +E+ IL D PS PG+ Sbjct: 9837 HWQPLGTSLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGR 9896 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLK 1444 P I I S+++ W P + G S+I Y++E ++ + WI + +T T ++ NL+ Sbjct: 9897 PTISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTTSQRWIKANHEPVTTTSHTLINLR 9956 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTC 1503 ++ Y FR A N + S+ S ++ V P V KP +N + + +TC Sbjct: 9957 EDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKP-QNAHVAEGKSVTVTC 10015 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 G P P+V WYR G+++ + N N G + Sbjct: 10016 QVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGTI 10075 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKE 1618 + + + P +T+ H + E+++ V G P P + W ++G + + Sbjct: 10076 TDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGR 10135 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 + I + + I+ + + + KY++ ASN G + + + + P P + EI Sbjct: 10136 FEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECL-EI 10194 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 + E++ + W PP+ DGG ++ Y +EK E W +V T + L + +Y Sbjct: 10195 TSEAIRLAWNPPIYDGGSNISSYMVEKREVGVLTWARVISSKNTHHT--VINLRSDTQYQ 10252 Query: 1739 FRVIAQNPVGFSEALESEPIV 1759 FRV A N G SE E+ ++ Sbjct: 10253 FRVTAFNMYGASEPCEATAVI 10273 Score = 137 bits (331), Expect = 4e-30 Identities = 146/650 (22%), Positives = 272/650 (41%), Gaps = 29/650 (4%) Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLKAENS 810 V L P T+ + +K + PT+ D H +KV+ + + K E + Sbjct: 149 VTLEKPTEAAPEETVFTLEPSKVDETAPTEVDFQIAHEKPEEHEEKVEIK-IMKKKPEET 207 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEI-------TVKEKGTIKLVARVTRNPVPS 863 E + E + T+E E +++ +++KG I++ +V R + + Sbjct: 208 EDVVEVKLTKKKKPLTKEEKEAEEIFELLKDVEPKNYEKVLRKKGIIQM--KVIRKHIEA 265 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEI-DSGDYKCV--ASNSAGKSSHGAR 920 + ++ E + + TQ + E V V SE+ ++ K V A A Sbjct: 266 VEKHKAEETVK--QLATQEVEAEVTLRVSEEVPSEVVEAAVIKPVEAAPVEAAPVKAVPE 323 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEG 979 + E+ F + L K + +G T L C+ + +W + K + D E+ ++G Sbjct: 324 KKLKPEEWKFTEEL-KPAKGFKGDTCELVCEVNDENAIVEWVKHGKVLKPSDKYELKEDG 382 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 D C + +T L V+ + + + L+ + E++ A+L E Sbjct: 383 TKRILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPV-KIVGDLKPLTITERETAVLTCE 441 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 +++ A V W +DGE I +KY+ G +KL I+N S D EY+C L S T Sbjct: 442 VSNTKAAVTWLKDGEPIDITLDKYEVLDEGRRKKLRIKNISPEDAAEYTCQLPRSSSTMT 501 Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 +TV E P E+++ L ATFE E+++ A V W K E+ S+ ++ DG+ Sbjct: 502 LTVNEKPLEVLSPLTKLFAYLTGNATFECEVSEPWANVTWLKGDKEVVPSDKYKMESDGR 561 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 +++ I DD +Y+C + + K +A L + E +I T + PE E Sbjct: 562 FRRMIIQGIAEDDVSDYTCVLRDKKTSADLLLRE-TIKIT-KPPEDEDSRERQSVKFVCE 619 Query: 1220 IPDET--LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 + + DV W K V+ ++ +I++ TL+I + D +Y+ ++ + + Sbjct: 620 LTGDAAKADVKWKKGGQVVRKDKRHKIINEGLVSTLVIEDLSPSDAGKYSVLVDNMEMPF 679 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKP 1336 L V+ ++ PP + + G +P P ++ + K I + Sbjct: 680 TLSVQALK-PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITPENSDVTF 738 Query: 1337 SID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 D ++ + +V DAG Y + +N G +V+ V+++ P PP Sbjct: 739 QFDEATQEHKVIFHEVTPKDAGKYLVIAKNESG--EVKQAVSMMVTPRPP 786 Score = 134 bits (325), Expect = 2e-29 Identities = 107/428 (25%), Positives = 189/428 (44%), Gaps = 26/428 (6%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 +K+ +R S YT+EA N G S+ + V D+P P+GP+ ++ I+ S T W PL Sbjct: 9757 VKDAEREDSGTYTLEAVNELGRHSITARVNVLDRPGPPQGPISIQSITNNSATFTWTLPL 9816 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DDGG + +Y + E + W + + + +KL +N Y+ RV A+N G S Sbjct: 9817 DDGGAPIQRYQVSIRESNRTHWQPLG--TSLLPNFTAKKLKDNTHYVLRVTAENQYGTSR 9874 Query: 1752 ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-E 1809 LE E I++K+ D PS I +SV+++W +GGS I Y +E + Sbjct: 9875 PLEIREAILVKSPFDPPS-APGRPTISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTT 9933 Query: 1810 GKKW-KXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL--TP 1865 ++W K + + L +T Y+FR+ A N +G S P T ++ + + P Sbjct: 9934 SQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVP 9993 Query: 1866 P---SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P S+P+N V+E S +VT + + Y + + G+ + + G++ Sbjct: 9994 PQFVSKPQNAHVAEGKSVTVT---CQVSGYPAPEVRWYRLGREIAHGRKFQ--IGGDGNI 10048 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 H + +D ++ N G +V + T+P+ P+ + ++G I Sbjct: 10049 HTLTANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHL-LLGEYI 10107 Query: 1983 VM--TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 ++ GTP P + ++ DV E+ K + IR +++ Sbjct: 10108 MLKVPFSGTPR-----PSIKWDRDGEDVVDGGRFEI-KATPHDTTLIIRGITKEDAGKYS 10161 Query: 2041 IYARNEIG 2048 + A NE+G Sbjct: 10162 VVASNELG 10169 Score = 127 bits (306), Expect = 4e-27 Identities = 120/471 (25%), Positives = 192/471 (40%), Gaps = 30/471 (6%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P EV W K+G ++ N + + I ++ + + KY+ E G S Sbjct: 9090 PNAEVKWMKDGFQIFGYDRVNEIKEGQRRAITLRNVGDRDTGKYSCEC----GKQSTSCW 9145 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 L V P+ + + T+ P G K +E H D A + Sbjct: 9146 LSVTAPPTIDVKAYKDVVVVKTGNTLRLLVPYT--GCPSPK--VEWHRHD-------ARI 9194 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP-----IVIKTALDVPSXXXXX 1773 D T+ I+ + + R + + G FS L +E I+ +DVP Sbjct: 9195 SEDTRTH-IETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAIIRVNVIDVPGPPTGP 9253 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSI 1831 + V ++W P + +GGSPI Y VE ++ ++ W + LS Sbjct: 9254 LEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMWTSVSNYVSHVPFTVSGLSE 9313 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 Y+FR+ A N G P + + I + P+ P +S +TL W+EP Sbjct: 9314 KVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEISNVQRDRMTLTWSEPSH 9373 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 +GG PI YIIE + K W ++ I+ + E FRISA N G+ P Sbjct: 9374 DGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIKGLTEGSNYEFRISAVNDTGIGNP 9433 Query: 1952 TE-SQSVRLEKH-ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 +E S +L + A P+PP AP+ I + + V SW P DGG+ + Y + R Sbjct: 9434 SEVSAPPKLARSPAGRPTPPGAPI-IGDITATSVSLSWSAPSTDGGSEITHYIVERRLKG 9492 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEPF 2059 MW++ + V+ ++ +L E+ Y R+ A N G S+P + E F Sbjct: 9493 SYMWID--RTVVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDPSRASESF 9541 Score = 109 bits (261), Expect = 1e-21 Identities = 70/229 (30%), Positives = 106/229 (46%), Gaps = 8/229 (3%) Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 T +F I NE G T+ ++ + PP+ P +++ V+L W P+ +G Sbjct: 9221 TGKFSITLTNEAGQE---TAIIRVNVIDVPGPPTGPLE--ITDVGRHCVSLSWEPPKDDG 9275 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 GSPI +Y +E + + WT + V + + EK E FR+ AEN GV P Sbjct: 9276 GSPIQSYTVEQREANRRMWTSVSNYVSHV-PFTVSGLSEKVEYEFRVCAENINGVGPPLH 9334 Query: 1954 S-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 + V + +VP+PP P EI V + + +W P DGG P+ GY I R+ Sbjct: 9335 GIEPVVIVAPYSVPTPPGKP-EISNVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQ 9393 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 W V + + F I+ L+E Y RI A N+ G+ P E P K+ Sbjct: 9394 WNRVNRDLIKDTTFTIKGLTEGSNYEFRISAVNDTGIGNPSEVSAPPKL 9442 Score = 105 bits (253), Expect = 1e-20 Identities = 120/527 (22%), Positives = 200/527 (37%), Gaps = 32/527 (6%) Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 A L +K E D+G Y L N G + V +LD+P PP P +I I ++S W Sbjct: 9753 AELYVKDAEREDSGTYTLEAVNELGRHSITARVNVLDRPGPPQGPISIQSITNNSATFTW 9812 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 P + G + I Y V +E + T W + + + LK N+ Y R A N+ Sbjct: 9813 TLPLDDGGAPIQRYQVSIRESNRTHWQPLGTSLLPNFTAKKLKDNTHYVLRVTAENQYGT 9872 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----R 1517 S E E V S + NI + + + T +T Y R Sbjct: 9873 SRPLEIREAILVKSPFDPPSAPGRPTISNIQRD-SVHVSWTAP-SSDGGSSITGYIIERR 9930 Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVG--IQQKPVI 1573 D + KA +E Y + +A N G E S V + + P+ Sbjct: 9931 DTTSQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPID 9990 Query: 1574 TISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 T+ + + + G VT + G P PEV WY+ G ++ + +++ I Sbjct: 9991 TVPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHT 10050 Query: 1630 IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDK---PSKPEGPVIMREISRESVT 1684 + +L + ++ +N G T + E+ + V K P++ P+ + + E + Sbjct: 10051 LTANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHL--LLGEYIM 10108 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + K P K+ + + + ++ D T I+ + + + V+A Sbjct: 10109 L--KVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT-TLIIRGITKEDAGKYSVVAS 10165 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N +G S + I D P I +E++ + W P +GGS I Y V Sbjct: 10166 NELGHDTC--SIQVNILRHPDSP----RNLECLEITSEAIRLAWNPPIYDGGSNISSYMV 10219 Query: 1805 EIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 E ++ G W + L +T YQFR+ A N G S P Sbjct: 10220 EKREVGVLTWARVISSKNTHHTVINLRSDTQYQFRVTAFNMYGASEP 10266 Score = 103 bits (248), Expect = 4e-20 Identities = 74/283 (26%), Positives = 122/283 (43%), Gaps = 8/283 (2%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 +P+PPG P I +I ++S+++ W P G S I +Y+VE + + WI + T S Sbjct: 9449 RPTPPGAPIIGDITATSVSLSWSAPSTDGGSEITHYIVERRLKGSYMWIDRTVVHDTSCS 9508 Query: 1440 IQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + NL + Y FR AVN + SD S +E + + +P++ ++N + Sbjct: 9509 VNNLVEDKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQT 9568 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR-XXXXXXXXXXXXXXXYKCIAFN 1554 C G P+PKV+W G++L + T +N Y IA N Sbjct: 9569 GMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKN 9628 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKL 1613 HG V +S + IQ+ P ++I + G E + + G P P W ++ + Sbjct: 9629 KHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGE- 9687 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 E D +TKE+ V EL ++Y + T T + Sbjct: 9688 ELDTRGRYSTKEQGRVHDF-ELPDLGGNRYPLSGFYTLKTEKL 9729 Score = 103 bits (246), Expect = 7e-20 Identities = 125/592 (21%), Positives = 231/592 (39%), Gaps = 39/592 (6%) Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 T +EL E + L++ G T E ++ +A V+W KDG +I + + +G++ Sbjct: 9059 TPIELA-EFVEPLKDVSAKAGKIVTLECRISNPNAEVKWMKDGFQIFGYDRVNEIKEGQR 9117 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVE 1219 + + + + D G+YSCE G + L+V P+I+ ++ NT L Sbjct: 9118 RAITLRNVGDRDTGKYSCECGKQSTSCWLSVTAPPTIDVKAYKDVVVVKTGNTLRLLVPY 9177 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT 1277 + V W++ + I + + + + + + IR D +++ L + + T Sbjct: 9178 TGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETA 9237 Query: 1278 KLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 ++V V++ P P E + ++ P + V + + T Sbjct: 9238 IIRVNVIDVPGPPTGPLEITDVGRHCVSLSWEPPKDDGGSPIQSYTVEQREANRRMWTSV 9297 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCG-----HA-DVEMNVTILDKPSPPGKPNIL 1390 S T+ + +++ EN G H + + V P+PPGKP I Sbjct: 9298 SNYVSHVPFTVSGLSEKVEYEFRVCAENINGVGPPLHGIEPVVIVAPYSVPTPPGKPEIS 9357 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSS 1448 + + + W EP + G I Y++E +E + +W V I T +I+ L S+ Sbjct: 9358 NVQRDRMTLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIKGLTEGSN 9417 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--IFG 1506 Y FR AVN+ I + SE + K+ + + P+ T + + + G Sbjct: 9418 YEFRISAVNDTGIGNPSEVSAPPKLARSPAGRPTPPGAPIIGDITATSVSLSWSAPSTDG 9477 Query: 1507 GVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE---- 1558 G ++T Y ++LK + T + ++ A N G Sbjct: 9478 G---SEITHYIVERRLKGSYMWIDRTVVHDTSCSVNNLVEDKEYTFRVTAVNAAGNESDP 9534 Query: 1559 -------VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 V S + G +I I N + + G + I G P P+V W +G Sbjct: 9535 SRASESFVAESQLPGAAPSILIEIQNAMVAE----GQTGMFMCKISGSPKPKVSWMHHGR 9590 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLK 1661 +L +++NIT I + + + YTI A N G+ SS E+ ++ Sbjct: 9591 ELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQ 9642 Score = 97.9 bits (233), Expect = 3e-18 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 9/217 (4%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + + A NE+G ++ ++ + PP P + + T+ S T WT P +GG+P Sbjct: 9768 YTLEAVNELGR---HSITARVNVLDRPGPPQGPIS--IQSITNNSATFTWTLPLDDGGAP 9822 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 I Y + + W + T + + +K+ + R++AEN G S P E + Sbjct: 9823 IQRYQVSIRESNRTHWQPLGT--SLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIRE 9880 Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 L K PS P P I + + V SW P DGG+ + GY I RD T W++ Sbjct: 9881 AILVKSPFDPPSAPGRPT-ISNIQRDSVHVSWTAPSSDGGSSITGYIIERRDTTSQRWIK 9939 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 V T + +L E+ Y R+ A N +G SEP Sbjct: 9940 ANHEPVTTTSHTLINLREDTEYEFRVMAENSMGASEP 9976 Score = 95.1 bits (226), Expect = 2e-17 Identities = 105/439 (23%), Positives = 182/439 (41%), Gaps = 37/439 (8%) Query: 1633 KELKRSHSSKYTIEASNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIE 1686 K+LK + + A N GTS +E+ + +D PS P P I I R+SV + Sbjct: 9852 KKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTISN-IQRDSVHVS 9910 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W P DGG +T Y IE+ + + RWIK ++ + L E+ EY FRV+A+N Sbjct: 9911 WTAPSSDGGSSITGYIIERRDTTSQRWIKANHEPVTTTSHTLINLREDTEYEFRVMAENS 9970 Query: 1747 VGFSE-ALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 +G SE + S+ ++++ +D P + +SV +T S G P + + Sbjct: 9971 MGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAHVAEGKSVTVTCQVS----GYPAPEVR 10026 Query: 1804 -VEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 + +E G+K++ +L + + N+ GT + + + + Sbjct: 10027 WYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGT-ITDAFELNVLV 10085 Query: 1860 GKTLTPPSQ---PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 LT P++ P + ++ E V T S +++ + K+ Sbjct: 10086 MPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT 10145 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 T+ I I ++D + + A N +G T S V + +H P P LE Sbjct: 10146 TL-------IIRGITKEDAGKYSVVASNELGHD--TCSIQVNILRH---PDSPRN-LECL 10192 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 + S + +W P +DGG+ + Y + R+V W V + + +L + Sbjct: 10193 EITSEAIRLAWNPPIYDGGSNISSYMVEKREVGVLTWARV--ISSKNTHHTVINLRSDTQ 10250 Query: 2037 YMIRIYARNEIGLSEPLES 2055 Y R+ A N G SEP E+ Sbjct: 10251 YQFRVTAFNMYGASEPCEA 10269 Score = 92.7 bits (220), Expect = 1e-16 Identities = 68/264 (25%), Positives = 109/264 (41%), Gaps = 5/264 (1%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 +V WY+ I KF + D TL + +D E + + + T E+ V Sbjct: 10024 EVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGGTITDAFELNV 10083 Query: 1285 EFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 PK+ R + G + L V + P+P+ +W + + + + Sbjct: 10084 LVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPH 10143 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 +L I+ + DAG Y + N GH + V IL P P LEI S +I + W Sbjct: 10144 DTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECLEITSEAIRLAW 10203 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 + P G S I Y+VE +E+ W V + T ++ NL++++ Y+FR A N Sbjct: 10204 NPPIYDGGSNISSYMVEKREVGVLTWARVISSKNTHHTVINLRSDTQYQFRVTAFNMYGA 10263 Query: 1462 SDASETTEYYKVIKETKIQSPTVE 1485 S+ E T K +K P E Sbjct: 10264 SEPCEATAVI-CTKSSKAGRPQFE 10286 Score = 86.2 bits (204), Expect = 9e-15 Identities = 83/356 (23%), Positives = 147/356 (41%), Gaps = 34/356 (9%) Query: 496 PVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 P+ E+ + + AP F++ L +G+ +FEC+V P ITWFR + S Sbjct: 10632 PLMERECYMDVRDAAPKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISI 10691 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----APLSDHGSE 610 ++M YDD TL++++ +D +TC A N+ G A+S+ L V+ L G Sbjct: 10692 KYKMLYDDHKY-TLIVQDSEFDDIDEYTCKAVNSYGHATSSASLDVQLLDAKELDSRGER 10750 Query: 611 MTVXXXXXXXXXXXXADIL---EGIPPTFSKKPK----AQYVDEGSDILLE-----CRLV 658 + A L + P+ K P+ + + G ++ + Sbjct: 10751 RGLDMKRKKIPLGERAKKLRKAQAEAPSSDKAPQLIRPLEDQECGFSFIMPLSFQVAEIP 10810 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 +PEP + W + + P + E +H L+I + +G YT N+ G Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVH----TLEIDGTTEKDKGQYTAEISNQYGS 10866 Query: 719 ASLPIVLKI------KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 + L + K + P L+ + + +G + L +V G P P I W K++ Sbjct: 10867 IATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDH 10926 Query: 773 KPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 K + ++ D +T S+ I++ ++D G YT A N G + + VE Sbjct: 10927 KEIFDGQHYSIEFGEDDETCSL-IIQEAFLQDAGTYTCLASNLLGRISCDSYVRVE 10981 Score = 83.4 bits (197), Expect = 6e-14 Identities = 142/656 (21%), Positives = 259/656 (39%), Gaps = 69/656 (10%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+ AP + +++ +G T F C++ G P+P+++W + P + + +D Sbjct: 9545 SQLPGAAPSILIEIQNAMVAEGQTGMFMCKISGSPKPKVSWMHHGRELMPGRKHNIT-ED 9603 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXX 621 + V +V+ V + G +T +AKN G S+ EL I P + Sbjct: 9604 NGVFKIVVFSVTDYETGMYTIIAKNKHGSVRSSAELLIQRPPQLSIDRHLQDLSVRAGQE 9663 Query: 622 XXXXADILEGIP-PTFS-KKPKAQYVDEGSDILL--ECRLVAIPEPDIA---------WL 668 + G P PTF+ ++ + +D + R+ PD+ + Sbjct: 9664 IHIPVTLTYGTPKPTFTWRRHDGEELDTRGRYSTKEQGRVHDFELPDLGGNRYPLSGFYT 9723 Query: 669 FKGEEIVPDENISVAIESDMHMYCSV-----LKITNVKKFQEGTYTVVAVNREGEASLPI 723 K E+++ + ++ + V L + + ++ GTYT+ AVN G S+ Sbjct: 9724 LKTEKLLRESGCGTTWANNNLLVNVVGGIAELYVKDAEREDSGTYTLEAVNELGRHSITA 9783 Query: 724 VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783 + + PPQ ++S I + + + P + + + + Sbjct: 9784 RVNV-LDRPGPPQGPISIQS-ITNNSATFTWTLPLDDGGAPIQRYQVSIRESNRTHWQPL 9841 Query: 784 GDTHSITILKPKKVKDEGVYTLK--AENSEGIA---ETSAVITVEEPTEENAEPPL-FIN 837 G T + KK+KD Y L+ AEN G + E I V+ P + + P I+ Sbjct: 9842 G-TSLLPNFTAKKLKDNTHYVLRVTAENQYGTSRPLEIREAILVKSPFDPPSAPGRPTIS 9900 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 Q +V T + + SIT Y II +T +Q + N E V T + Sbjct: 9901 NIQRDSVHVSWTAP-----SSDGGSSITGY----IIERRDTTSQRWIKANHEPVTTTSHT 9951 Query: 898 EID-----SGDYKCVASNSAGKSSHGA-------RVTIDVEKVTFVKHLQKSYETEEGKT 945 I+ +++ +A NS G S R ID FV Q ++ EGK+ Sbjct: 9952 LINLREDTEYEFRVMAENSMGASEPSTVSQRVLVRDPIDTVPPQFVSKPQNAH-VAEGKS 10010 Query: 946 VILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 V + CQ S +WY +EI+ +I +G DVG I V + Sbjct: 10011 VTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTN 10070 Query: 1004 Q--------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGE 1054 + E + +++ K T+P +R + + +L+V + + + W+RDGE Sbjct: 10071 KGGTITDAFELNVLVMPKLTLPARLRT--PIHLLLGEYIMLKVPFSGTPRPSIKWDRDGE 10128 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELP 1106 + +++ + H L IR + D G+YS + +E +C+ +V ++ P Sbjct: 10129 DVVDG-GRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHP 10183 Score = 79.8 bits (188), Expect = 8e-13 Identities = 47/136 (34%), Positives = 66/136 (48%), Gaps = 6/136 (4%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I N+ D F I+ N G E+ +R+ VP PPT PLEI VG + V S Sbjct: 9213 IRNVVRGDTGKFSITLTNEAG----QETAIIRVNV-IDVPGPPTGPLEITDVGRHCVSLS 9267 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ DGG+P+ Y + R+ + MW V V+ + F + LSE Y R+ A N Sbjct: 9268 WEPPKDDGGSPIQSYTVEQREANRRMWTSVSNY-VSHVPFTVSGLSEKVEYEFRVCAENI 9326 Query: 2047 IGLSEPLESDEPFKVI 2062 G+ PL EP ++ Sbjct: 9327 NGVGPPLHGIEPVVIV 9342 Score = 77.8 bits (183), Expect = 3e-12 Identities = 109/528 (20%), Positives = 203/528 (38%), Gaps = 37/528 (7%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEAS-----LPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + +++ + + +E + V AVN+ G ++ P++++ + + + + VR Sbjct: 8722 TTIRVPRLSEGKEYEFRVSAVNKAGMSTPAATAAPVIVERPSYAPKIDLGSQFRDVITVR 8781 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITIL-KPKKVKDEGVYTL 805 G L + G P PT+ W + K V K+ T+S + K + D G YT+ Sbjct: 8782 AGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTYTI 8841 Query: 806 KAENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITV-----KEKGTIKLVARVTRN 859 K N G T V +++P+ + +T+ K+ G + + Sbjct: 8842 KISNKAGTDTATIRVAVLDKPSAPEGPIKVTSITCDSVTLAWEPPKDDGGADITGYILER 8901 Query: 860 PVPS-ITWYR-NNEIISPSETITQNFDGEN----IELVITNVDSE-IDSGDYKCVASNSA 912 P W R + + SP +T DG + + V +SE +++ D + S Sbjct: 8902 REPDQFRWTRVTSTLSSPRYAVTGLKDGRSYLFRVRAVSKYGESEPLETEDAILIKSAFE 8961 Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH-NKKEISGMD 971 + G +V + Q + + + T T+W +K++ + Sbjct: 8962 KPPAPGVPKASNVRDDSITLSWQPPHSDGGAEIHNYILEIKETRGTRWLRATRKQLKSPN 9021 Query: 972 HREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQDFEV 1028 R + +GR +G +TS +V K I EF+ L+D Sbjct: 9022 FRVTGLSKGREYEFRVAAENEAGLGAFS------KTSAPIVSKTPIELAEFVEPLKDVSA 9075 Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 K + LE I++ A+V W +DG I ++ + K G R + +RN D G+YS Sbjct: 9076 KAGKIVTLECRISNPNAEVKWMKDGFQIF-GYDRVNEIKEGQRRAITLRNVGDRDTGKYS 9134 Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQ--KVNKGNKATFEIELTK-GDALVRWFKDGSE 1145 C +S + ++V PP I + V GN + T V W + + Sbjct: 9135 CECGKQSTSCWLSVT-APPTIDVKAYKDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDAR 9193 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTV 1191 I + + ++ I + D G++S + N + TAI+ V Sbjct: 9194 ISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAGQETAIIRV 9241 Score = 73.3 bits (172), Expect = 7e-11 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 7/179 (3%) Query: 1321 WIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +I+ K+ K T+ + D+ S T++ + + +++ N G V I Sbjct: 4721 YIIEKKV-KGEPWTQVTTDTVDGTSFTVRGLPEDEDVEFRISAVNKAGAGSPSNTVVIAF 4779 Query: 1380 KP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436 KP PPG P + ++D +S+ + W P+ G S +I Y+VE +E W+ + + + Sbjct: 4780 KPPGPPGTPEVSDVDKTSVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREV 4839 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 SI +L + Y FR A N+V + S +E +++ + + P+ K LK P Sbjct: 4840 TMSITDLVEKNEYEFRVIAENKVGPGEPSSPSE--RIVAKAPYEVPSPPKSLKATDLTP 4896 Score = 71.7 bits (168), Expect = 2e-10 Identities = 53/228 (23%), Positives = 102/228 (44%), Gaps = 16/228 (7%) Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +++ T ++++ E++ ++ V + K K PP++ KR S ++ Sbjct: 3375 IEETTFLVKRLKENENYQFRVVAHNLAGPGKPKAPKPPTPPEV---------KRLSPTSV 3425 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKH---TKPSIDS-KSASLTIKKVENTDAGIYKLRLE 1363 +++ A + + KK K T + DS + S T+K ++ + +++ Sbjct: 3426 QLNWSAPTSDGGSEVTAYIVEKKDKSGRWTPVTSDSIEDTSFTVKGLKEGEDVEFRVSAV 3485 Query: 1364 NNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 N G E+ V PS P KP + +I +S + W P+N G S + Y VE +E Sbjct: 3486 NKAGTGKPSEVTVIAAKPPSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREK 3545 Query: 1423 DTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 +W+ V K +T+T + +L ++Y FR A N +AS+ + Sbjct: 3546 GRDQWVRVNRKPVTETTMKVPDLVEKNNYEFRVIAENRAGPGEASDAS 3593 Score = 66.1 bits (154), Expect = 1e-08 Identities = 56/202 (27%), Positives = 93/202 (46%), Gaps = 15/202 (7%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVV---GNPRPTITWCKNNKPVKALPT----KSDGDTH 787 PQ+I PL+ + LS QV G P P + W ++P+K + DG H Sbjct: 10783 PQLIRPLEDQECGFSFIMPLSFQVAEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDG-VH 10841 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE---PTEENAEPPLFINRFQEITV 844 ++ I + KD+G YT + N G T + V E ++ P F ++I + Sbjct: 10842 TLEIDGTTE-KDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFI 10900 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSG 902 E +L +VT P P+I W+++++ I + + F D E L+I + D+G Sbjct: 10901 VEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQ-DAG 10959 Query: 903 DYKCVASNSAGKSSHGARVTID 924 Y C+ASN G+ S + V ++ Sbjct: 10960 TYTCLASNLLGRISCDSYVRVE 10981 Score = 65.3 bits (152), Expect = 2e-08 Identities = 39/133 (29%), Positives = 68/133 (51%), Gaps = 8/133 (6%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 ++ + A NE+G T ++ I L P PRN E TS ++ L W P +GGS Sbjct: 10159 KYSVVASNELGHD---TCSIQVNI---LRHPDSPRNLECLEITSEAIRLAWNPPIYDGGS 10212 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 I++Y++E + V +W ++++ + H H + N++ + FR++A N G S P E+ Sbjct: 10213 NISSYMVEKREVGVLTWARVIS-SKNTH-HTVINLRSDTQYQFRVTAFNMYGASEPCEAT 10270 Query: 1956 SVRLEKHATVPSP 1968 +V K + P Sbjct: 10271 AVICTKSSKAGRP 10283 Score = 64.1 bits (149), Expect = 4e-08 Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 7/135 (5%) Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILEI 1392 TK ID + TIK ++ + +++ N G + P PP P+I ++ Sbjct: 5033 TKDIIDD--TNFTIKGLKEGEEAEFRVVAVNKAGSGKPSQTTVLAALPPGPPESPSISDV 5090 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450 +S+ + W PE+ G S II Y+VE + D W+ V + +T + +L S Y Sbjct: 5091 KQTSVTLSWTPPESDGGSKIIGYIVEKK--DMGRWVKVNRSPVRETTMVVTDLVEKSEYE 5148 Query: 1451 FRAYAVNEVDISDAS 1465 FR A N+V + + S Sbjct: 5149 FRVMAENKVGVGEPS 5163 Score = 63.7 bits (148), Expect = 5e-08 Identities = 44/155 (28%), Positives = 67/155 (43%), Gaps = 11/155 (7%) Query: 1349 KVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINI 1399 KV N G +++R EN G + ++ I+ D P P KP + +S+ + Sbjct: 5828 KVTNLKTGSEYEFQVRAENKAGEGEPIQSTKPIVAKDAYDVPDAPEKPEPSSLTETSVTL 5887 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVN 1457 W P + G S I Y+VE +E T W++ I KT ++ +L+ S Y FR A N Sbjct: 5888 TWSPPASDGGSQITGYIVEKKEDFMTRWVNATRDAIHKTTLTLNDLREGSEYTFRVIAEN 5947 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 + S SE +K K + NIT Sbjct: 5948 KAGQSKPSEPCRPFKAKKPYGVPDTPGSPEASNIT 5982 Score = 62.9 bits (146), Expect = 9e-08 Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 8/123 (6%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADV-EMNVTILDKPS-----PPGKPNILEIDSSSI 1397 + T+ K++ DA +++ N G + +VT+ KP P +P +E+D+ SI Sbjct: 6127 TFTVPKLKEGDAVQFRVTAVNKAGPGKPSQSSVTVTLKPEFTVPEAPSQPTAVEVDAVSI 6186 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 + W P+N G S I Y++E +E ++ W +S K ++ + LK N + FR A Sbjct: 6187 TVRWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKENQTLEFRVIA 6246 Query: 1456 VNE 1458 VN+ Sbjct: 6247 VNK 6249 Score = 61.3 bits (142), Expect = 3e-07 Identities = 48/200 (24%), Positives = 85/200 (42%), Gaps = 23/200 (11%) Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 ++ G P P++ W+ + +KP + +Y++D V TL I +D G +T N G Sbjct: 10808 EIPGMPEPKVKWYHEDRPLKPGAHYH-FYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGS 10866 Query: 592 ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 ++ L V +E+ + P F + ++ EGS Sbjct: 10867 IATKCRLDV--------NELFLTKFKDYRK------------PHFDLHLRDIFIVEGSAA 10906 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 L+C++ +PEP+I W +EI ++ S+ D CS++ I GTYT + Sbjct: 10907 RLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDET-CSLI-IQEAFLQDAGTYTCL 10964 Query: 712 AVNREGEASLPIVLKIKTGE 731 A N G S ++++ E Sbjct: 10965 ASNLLGRISCDSYVRVERTE 10984 Score = 60.1 bits (139), Expect = 7e-07 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 7/120 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKT 1436 D PS PG P I +I +S+ + W P + G + I +++E ++ W V + KT Sbjct: 6471 DVPSAPGTPKISDITGTSLVLTWTPPSSDGGTEITNFIIELRD-RYGRWTRVNRTQVLKT 6529 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494 ++ NL SY FR A N++ + S++T+ KV + P E + N+T + Sbjct: 6530 GFNVMNLSEGDSYEFRVTAENKMGVGKPSDSTQ--KVTAKPPYSQPAAPNEPQISNVTAD 6587 Score = 59.3 bits (137), Expect = 1e-06 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 4/134 (2%) Query: 1336 PSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEID 1393 P I+S++ S T+K + + + +++ N G T+ KP P P + +ID Sbjct: 3073 PVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQVATLSAKPPGAPDAPEVSDID 3132 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITK-TQTSIQNLKTNSSYRF 1451 +S + W P G STI Y +E +E W V K++ K T + +L + Y F Sbjct: 3133 RTSATVIWTVPSLDGGSTITGYTIERREKGRDRWTRVNKSLVKDTTLKVNDLTEKNQYEF 3192 Query: 1452 RAYAVNEVDISDAS 1465 R A N+V + S Sbjct: 3193 RVIAENKVGPGEPS 3206 Score = 58.4 bits (135), Expect = 2e-06 Identities = 27/93 (29%), Positives = 44/93 (47%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 D P P +P++ +ID + + + W P + G S I Y+VE +E ++ W V T Sbjct: 5176 DVPDKPDQPDVTDIDKNEMTVKWSSPYSDGGSKITGYIVEMKEPYSSRWSQVTKTTDFTF 5235 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 + L Y+FR A N+ S SE + + Sbjct: 5236 KVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTF 5268 Score = 58.0 bits (134), Expect = 3e-06 Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 17/184 (9%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKE----PPQVIEPLKSMIVRQGES 751 + N+ + +E T+ V AVN G S P + E + P ++ +++ +V +G++ Sbjct: 9509 VNNLVEDKEYTFRVTAVNAAGNESDPSRASESFVAESQLPGAAPSILIEIQNAMVAEGQT 9568 Query: 752 VILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + ++ G+P+P ++W + + P + D I + + G+YT+ A+ Sbjct: 9569 GMFMCKISGSPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDY-ETGMYTIIAK 9627 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVT-RNPVPSITW 866 N G +SA + ++ P P L I+R Q+++V+ I + +T P P+ TW Sbjct: 9628 NKHGSVRSSAELLIQRP------PQLSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTW 9681 Query: 867 YRNN 870 R++ Sbjct: 9682 RRHD 9685 Score = 54.8 bits (126), Expect = 2e-05 Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 6/139 (4%) Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPPGKPNILEI 1392 + P +D K T+ V++ + + N G +V++ + P PPG P + Sbjct: 5328 SSPILDLK---FTVTNVQDDAECEFHVIAINKAGEGKPSPSVSLTFRLPGPPGTPEVYNP 5384 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYR 1450 S+++ W P G + II Y +E E+ W+ + +I + + +L N ++ Sbjct: 5385 SDKSVDLRWTPPTEQGGTRIIGYFIEKCEVGKDNWVRINRSSIREANYVVGDLTLNCRFK 5444 Query: 1451 FRAYAVNEVDISDASETTE 1469 FR A N + S+ +E Sbjct: 5445 FRVCAENRAGVGPPSDYSE 5463 Score = 54.4 bits (125), Expect = 3e-05 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 9/192 (4%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 +PP+ +++ QN V +G T +++ A VRW++ G EI Q+ DG L Sbjct: 9992 VPPQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTL 10051 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPAN--TDAYLTVEI 1220 +D GE S V N T E + L LP + P + Y+ +++ Sbjct: 10052 TANQLFPEDVGEISVTVTNKGGTITDAFELNVLVMPKLTLPARLRTPIHLLLGEYIMLKV 10111 Query: 1221 P---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275 P + W + + D +F + + TLIIR T++D +Y+ V + Sbjct: 10112 PFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELGHD 10171 Query: 1276 TTKLKVEVVEFP 1287 T ++V ++ P Sbjct: 10172 TCSIQVNILRHP 10183 Score = 54.0 bits (124), Expect = 4e-05 Identities = 53/242 (21%), Positives = 97/242 (40%), Gaps = 12/242 (4%) Query: 803 YTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 + + AENS G +E S V + V +P + PP F+++ Q V E ++ + +V+ Sbjct: 9963 FRVMAENSMGASEPSTVSQRVLVRDPID--TVPPQFVSKPQNAHVAEGKSVTVTCQVSGY 10020 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P + WYR I+ DG NI + N D G+ +N G + Sbjct: 10021 PAPEVRWYRLGREIAHGRKFQIGGDG-NIHTLTANQLFPEDVGEISVTVTNKGGTITDAF 10079 Query: 920 RVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREII 976 + + V K+T L+ G+ ++L+ S T S KW + +++ EI Sbjct: 10080 ELNVLVMPKLTLPARLRTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIK 10139 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 D G + ++ +T ++ V P+ R L+ E+ + + Sbjct: 10140 ATPHDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNILRHPDSPRNLECLEITSEAI 10199 Query: 1034 AI 1035 + Sbjct: 10200 RL 10201 Score = 52.4 bits (120), Expect = 1e-04 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 2/118 (1%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 D P P + +SS ++ W P + G S + Y VE ++ + W V + T+T Sbjct: 7375 DTPDAPESVQVTGTTASSASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVNRVPVTET 7434 Query: 1439 S--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 + + +LK Y+FR A N I +S++T+ + S +E + +IT + Sbjct: 7435 NMVVGDLKEGLQYQFRVCAENRAGIGRSSDSTKPTVIKDPVDAPSAPLEPTIASITAD 7492 Score = 52.0 bits (119), Expect = 2e-04 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 3/94 (3%) Query: 1091 LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFS 1149 L + C +V + P+ I L+N +GN FE E++ + L+ WF+ E+ S Sbjct: 10633 LMERECYMDVR--DAAPKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIIS 10690 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++ D K L + D + DD EY+C+ NS Sbjct: 10691 IKYKMLYDDHKYTLIVQDSEFDDIDEYTCKAVNS 10724 Score = 49.6 bits (113), Expect = 0.001 Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 2/93 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATL 568 P+F K + T +G + F + GYP P+I + + I P + D +D+ Sbjct: 689 PVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITPENSDVTFQFDEATQEHK 748 Query: 569 VI-REVFPEDAGTFTCVAKNAAGFASSTTELIV 600 VI EV P+DAG + +AKN +G ++V Sbjct: 749 VIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMV 781 Score = 49.2 bits (112), Expect = 0.001 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 10/129 (7%) Query: 1340 SKSASLTIKKVENTDAGIYKLRL--ENNCGHADV-EMNVTILDK-----PSPPGKPNILE 1391 +K+ T K T+ Y+ R+ EN G + E + T K P P P + + Sbjct: 5228 TKTTDFTFKVTRLTEGKDYQFRIIAENKAGQSQPSEPSRTFTAKLPFGVPGAPDTPELTD 5287 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449 I S+ + W P + G S I+ Y VE ++ +T W VK+ I + ++ N++ ++ Sbjct: 5288 IKDFSLTVKWLAPTSDGGSPILGYFVEQKDQFSTRWQRVKSSPILDLKFTVTNVQDDAEC 5347 Query: 1450 RFRAYAVNE 1458 F A+N+ Sbjct: 5348 EFHVIAINK 5356 Score = 48.8 bits (111), Expect = 0.002 Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 10/114 (8%) Query: 815 ETSAVITVEEPTEENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 E S + VE+P +P ++ RF++ IT++ T ++ P P+++W +N + Sbjct: 8453 EPSNTVMVEDPA---VKPKFNLDARFEKVITIRAGHTFRIDIPYKATPTPTVSWTQNGDT 8509 Query: 873 ISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDV 925 + S IT D N +T +E DSGDY ASN AG+ + VT++V Sbjct: 8510 VQKSNRIT--IDSNNYGTTLTARTAERTDSGDYVIRASNKAGEDT--VTVTVNV 8559 Score = 48.0 bits (109), Expect = 0.003 Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 21/186 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI----NSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 P+ IR L+D E + L ++ V W + +KP + + +E+ G + Sbjct: 10783 PQLIRPLEDQECGFSFIMPLSFQVAEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDG-VH 10841 Query: 1073 KLYIRNTSVHDEGEYSCILRDE------SCTAEVTVVELP-------PEIITRLQNQKVN 1119 L I T+ D+G+Y+ + ++ C +V + L P L++ + Sbjct: 10842 TLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVNELFLTKFKDYRKPHFDLHLRDIFIV 10901 Query: 1120 KGNKATFEIELTK-GDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEY 1176 +G+ A + ++T + +RWFKD EI H I+ D + L I + L DAG Y Sbjct: 10902 EGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTY 10961 Query: 1177 SCEVGN 1182 +C N Sbjct: 10962 TCLASN 10967 Score = 46.8 bits (106), Expect = 0.007 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 6/115 (5%) Query: 1358 YKLRLENNCGHA--DVEMNVTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 +++ EN G + E++VT + P P N+ +S + W P++ G S I Sbjct: 2997 FRVIAENKAGQSKPSPELHVTAKYPFETPQAPTIDNVTRESPTSATVKWSPPKSDGGSEI 3056 Query: 1413 IYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 YV+E +E + W V ++ T+T +++ L + FR AVN+ S+ Sbjct: 3057 TGYVLEKKEKMSPRWSPVIESETETSFTVKGLPDGENVEFRVSAVNKAGTGKPSQ 3111 Score = 45.6 bits (103), Expect = 0.015 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 3/127 (2%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F+ KPKA EG + + P P+I + +EI P EN V + D Sbjct: 688 PPVFTTKPKAVDTQEGMSAIFRYVIAGYPVPEIKFTKDWKEITP-ENSDVTFQFDEATQE 746 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + V G Y V+A N GE + + + + P ++++ S+ R + Sbjct: 747 HKVIFHEVTPKDAGKYLVIAKNESGEVKQAVSMMVT--PRPPEELMKRKMSLKARASQQE 804 Query: 753 ILSAQVV 759 I + + Sbjct: 805 IFEDEEI 811 Score = 45.2 bits (102), Expect = 0.020 Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 18/172 (10%) Query: 1507 GVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 G+P+PKV WY + + LK + + Y N +G + T Sbjct: 10811 GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATK 10870 Query: 1563 CVVGIQQKPVITISNEDIKQKH---KVGDEWLV-------TAVIEGIPPPEVIWYKNGNK 1612 C + + + + +D ++ H + D ++V + G+P P + W+K+ + Sbjct: 10871 CRLDVNE--LFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKE 10928 Query: 1613 LENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + + + Y+I E +T + I+E + YT ASN G S + ++V Sbjct: 10929 IFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980 Score = 44.4 bits (100), Expect = 0.035 Identities = 50/212 (23%), Positives = 85/212 (40%), Gaps = 21/212 (9%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAI 684 AD+L +K P+ + E + C L + D+ W G+ + D+ + Sbjct: 589 ADLLLRETIKITKPPEDEDSRERQSVKFVCELTGDAAKADVKWKKGGQVVRKDKRHKIIN 648 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E S L I ++ G Y+V+ N E +P L ++ +PP K++ Sbjct: 649 EG----LVSTLVIEDLSPSDAGKYSVLVDNME----MPFTLSVQA--LKPPVFTTKPKAV 698 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV------- 797 ++G S I + G P P I + K+ K + P SD + KV Sbjct: 699 DTQEGMSAIFRYVIAGYPVPEIKFTKDWKEI--TPENSDVTFQFDEATQEHKVIFHEVTP 756 Query: 798 KDEGVYTLKAENSEG-IAETSAVITVEEPTEE 828 KD G Y + A+N G + + +++ P EE Sbjct: 757 KDAGKYLVIAKNESGEVKQAVSMMVTPRPPEE 788 Score = 43.2 bits (97), Expect = 0.081 Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 2/110 (1%) Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 ++ PV P + + F E+L+P G T + C+V + W + ++K Sbjct: 313 VEAAPVKAVPEKKLKPEEWKFTEELKPAKGFKGDTCELVCEVND-ENAIVEWVKHGKVLK 371 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 PS +++ +D LVI++ P D +TC AS ++ V+ Sbjct: 372 PSDKYELK-EDGTKRILVIKDAVPVDGARYTCQLPKTKTGASLDVQIPVK 420 Score = 42.3 bits (95), Expect = 0.14 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G +E IP P + W F G + P +I + D S + + NV+K G Sbjct: 8186 GESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRI----DTSNRASTITVKNVEKANGGR 8241 Query: 708 YTVVAVNREGEASLPIVLKI 727 YT+ N G SL + +++ Sbjct: 8242 YTINLKNTAGAESLDVEVRV 8261 Score = 42.3 bits (95), Expect = 0.14 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 13/164 (7%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVV 1284 V WY + ++ + + TL I TE D+ +YT + + + TK +++V Sbjct: 10817 VKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDVN 10876 Query: 1285 E-FPPKIVDYE--------REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 E F K DY R+ I GS L P+PN W + K I +H Sbjct: 10877 ELFLTKFKDYRKPHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYS 10936 Query: 1336 PSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 D ++ SL I++ DAG Y N G + V + Sbjct: 10937 IEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV 10980 Score = 41.1 bits (92), Expect = 0.33 Identities = 52/243 (21%), Positives = 99/243 (40%), Gaps = 19/243 (7%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVRQ 748 + +++T++++ + V AVN+ G++ P+ +K+K P +PL + + Sbjct: 8026 TTVRVTSLQEGASYVFRVFAVNKIGDSE-PLETKETIKLKKKYDVPEAPSKPLVTNVTSD 8084 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA-----LPTKSDGDT-HSITILKPKKVK-DEG 801 ++ + P + K + + T S G T H I P+ ++ +E Sbjct: 8085 SVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRI----PRLMRGEEY 8140 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNP 860 + + AEN G S + E+ P F RF E I K + ++ T P Sbjct: 8141 EFRVSAENRAGPGPASTP-SAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIP 8199 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P++TW + + PS I + + + NV+ + + G Y N+AG S Sbjct: 8200 TPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVE-KANGGRYTINLKNTAGAESLDVE 8258 Query: 921 VTI 923 V + Sbjct: 8259 VRV 8261 Score = 40.7 bits (91), Expect = 0.43 Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 2/94 (2%) Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 P H G + + G PRP I W R + F++ + TL+IR + ED Sbjct: 10098 PIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDT-TLIIRGITKED 10156 Query: 578 AGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSE 610 AG ++ VA N G + + ++ I+ P S E Sbjct: 10157 AGKYSVVASNELGHDTCSIQVNILRHPDSPRNLE 10190 Score = 39.5 bits (88), Expect = 0.99 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 4/100 (4%) Query: 503 SEEQSMAPIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 +E+ ++ P F + P G + + E G P P +TW +KPS ++ D Sbjct: 8164 AEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRI--D 8221 Query: 562 DDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 N +T+ ++ V + G +T KN AG S E+ V Sbjct: 8222 TSNRASTITVKNVEKANGGRYTINLKNTAGAESLDVEVRV 8261 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/135 (21%), Positives = 57/135 (42%), Gaps = 3/135 (2%) Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 V + A +E ++ V E A P + I Q V E T + +++ +P Sbjct: 9522 VTAVNAAGNESDPSRASESFVAESQLPGAAPSILIE-IQNAMVAEGQTGMFMCKISGSPK 9580 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P ++W + + P D ++V+ +V ++ ++G Y +A N G A + Sbjct: 9581 PKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSV-TDYETGMYTIIAKNKHGSVRSSAEL 9639 Query: 922 TID-VEKVTFVKHLQ 935 I +++ +HLQ Sbjct: 9640 LIQRPPQLSIDRHLQ 9654 Score = 38.3 bits (85), Expect = 2.3 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 6/115 (5%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196 V+W KDGS +Q S+ I++ + + I +C +D G + +V N+ + +T+ + Sbjct: 7907 VKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSNTAGSDAITIRVQVL 7966 Query: 1197 NFTLRLPEFILVP---ANTDAYLTVEIPDET--LDVTWYKKKSVIEDTEKFTLIS 1246 + P LV +TD +L+ + P +T +T Y + ED +T ++ Sbjct: 7967 D-RPEQPRGPLVAKDIGSTDLFLSWKEPADTGGSPITHYIIERREEDRTSWTRLT 8020 Score = 37.9 bits (84), Expect = 3.0 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 6/93 (6%) Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSD-GDTHSITILKPKKVKDE 800 +M+VR G + L P+PT+ W K+ ++A K D D +I +K +DE Sbjct: 7884 TMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDE 7943 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 G + L N+ G S IT+ + E P Sbjct: 7944 GSFKLDVSNTAG----SDAITIRVQVLDRPEQP 7972 Score = 37.5 bits (83), Expect = 4.0 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTFT 582 G+T++ G P P++ W R A I S+D + + + DN + IR V D G F+ Sbjct: 9168 GNTLRLLVPYTGCPSPKVEWHRHDARI--SEDTRTHIETRDNRTQITIRNVVRGDTGKFS 9225 Query: 583 CVAKNAAGFASSTTEL-IVEAP 603 N AG ++ + +++ P Sbjct: 9226 ITLTNEAGQETAIIRVNVIDVP 9247 Score = 37.5 bits (83), Expect = 4.0 Identities = 19/69 (27%), Positives = 30/69 (43%) Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 A I G+P P+V WY L+ Y+ ++ + I +YT E SN G+ Sbjct: 10807 AEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYGS 10866 Query: 1654 SSVEVTLKV 1662 + + L V Sbjct: 10867 IATKCRLDV 10875 Score = 36.7 bits (81), Expect = 7.0 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284 +TW++ K + + K+ ++ D K TLI++ DD EYTC +++ +T+ ++V Sbjct: 10678 ITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEFDDIDEYTCKAVNSYGHATSSASLDVQ 10737 Query: 1285 EFPPKIVDYEREYR 1298 K +D E R Sbjct: 10738 LLDAKELDSRGERR 10751 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%) Query: 502 TSEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 T++ + A FV+ L + T+ EC++ P W++ +I ++ Sbjct: 1074 TADLKVQAAEFVKPLNNTSAAEYDETIVLECELSNELVP-CQWYKDDVLITVGPKVEVI- 1131 Query: 561 DDDNVATLVIREVFPEDAGTFTCV 584 DD LV+ +V PED G F CV Sbjct: 1132 DDGKKRKLVLHDVRPEDTGNFRCV 1155 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 3/94 (3%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P FI + E + V+ P ITW+R + + S +D L++ Sbjct: 10647 PKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIV 10706 Query: 893 TNVDSEIDSGD-YKCVASNSAGKSSHGARVTIDV 925 DSE D D Y C A NS G ++ A + + + Sbjct: 10707 Q--DSEFDDIDEYTCKAVNSYGHATSSASLDVQL 10738 >UniRef50_A6BM71 Cluster: Connectin; n=8; Gallus gallus|Rep: Connectin - Gallus gallus (Chicken) Length = 8074 Score = 344 bits (845), Expect = 2e-92 Identities = 348/1452 (23%), Positives = 607/1452 (41%), Gaps = 102/1452 (7%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +LEG P F+ K + E +++L+C + P + W+ G+ I P +N V I++D Sbjct: 6250 VLEG-DPYFTGKLQDYTAVEKDEVILQCEISKADAP-VKWMKDGKPITPSKN--VVIKAD 6305 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 +LK K G YT + A+L I E ++I PL S+ V Sbjct: 6306 GKKRILILK--KALKKDIGQYTCDCGTDQTSANLNI-------EDRDIEIIRPLYSVEVI 6356 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYT 804 + E+ ++ W +P+ P K +G H +T+ + + GV Sbjct: 6357 ETETARFDIEI-SEEGVHGNWKLKGEPLTESPDCEIKEEGKKHFLTLYNVRLDQAGGV-D 6414 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 +A N A++ A + V+ P PL +++TV + ++ +P + Sbjct: 6415 FQAAN----AKSGAHLRVK-PRVIGLLRPL-----KDVTVTAGESATFDCELSYEGIP-V 6463 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 WY + + PS+ + +G L++ +V D+G+ A + + A + + Sbjct: 6464 EWYLQGKKLEPSDKVVTRAEGRAHTLILRDVKLT-DAGEVSLTAKDFRTQ----ANLFVK 6518 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXX 983 V F K L+ EE T ILEC+ S KW+ N +EI +II EGR Sbjct: 6519 EPPVEFTKPLEDQ-TVEEEATAILECEVSRENAKVKWFKNGEEIHKTKKYDIISEGRVRK 6577 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV-AILEVEINS 1042 D C KD +TS L V+ EF+R L D EVKEK + ++L V+ + Sbjct: 6578 LIIHGCTLDDAKTYTCDAKDFKTSCFLNVEPLRVEFLRPLTDLEVKEKRICSVLNVKFLA 6637 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 + V W +DG I+ +K +YD +G R L I DE EY+C + + +TV Sbjct: 6638 QGVKVKWFKDG--IEIEKAEYDIISKGAERILVISKCLFDDEAEYACEAKTARTSGLLTV 6695 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 +E L + +VN+ E++K +A V WFK E+ + DG+K+ Sbjct: 6696 IEEEAVFTKNLHDLEVNENETVRLICEISKPNAEVTWFKGDEEVPDGGRFEYISDGRKRI 6755 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 L I + +DAG+Y+C++ +S T LTV E + F R P+ + V A + Sbjct: 6756 LVIRNAHPEDAGKYTCKLPSSSTTGKLTVHELAAEFLTR-PQNLEVLEGDKAEFACSVSK 6814 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 E + V W +V+E +K+ +ISD KKRTL+++ D +YT ++ +AK+T +L V Sbjct: 6815 EAITVQWLWGDTVLEPGDKYDIISDGKKRTLVVKDSVVGDAGKYTVMVGEAKATARLTV- 6873 Query: 1283 VVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSID 1339 +E K DY ++ + G ++ + ++W N + I K+ D Sbjct: 6874 -IE---KTQDYNSLKDQEVNEGQEIIFNCEVNK-EGAKEKWYKNGEAIFDSAKYIIVQKD 6928 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 +L I+ + D Y + L N+ G HA+ +T+L++ +P Sbjct: 6929 LVY-TLRIRDTQLKDQATYSISLSNHRGEHAESSAALTVLEEGLRIVEP----------- 6976 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 ++ E T+ ++ + T +W KN + + + L Y+ + + + Sbjct: 6977 --LEDIETMEKKTVTFWCKVNRLNATLKW--TKNGEEITFNKRILYKIDKYK-HSLIIKD 7031 Query: 1459 VDISDASE---TTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKV 1513 D E T K + E I + + L++ T +D TC + V Sbjct: 7032 CGFKDEGEYTVTAGQDKSVAELLITEAPADFIEHLQDQTVTEFDDAVFTCQLSK-EKASV 7090 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 WYR+G+++K K + +C + ++ + +++ PV Sbjct: 7091 KWYRNGREIKEGKKYQFEKDGNLHRLIIKDCRLDDECEYSCGVDDRKSRARLFVEEIPVE 7150 Query: 1574 TISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I +D+ + ++ +G+ EV W +N + ++ + ++ K +++ Sbjct: 7151 IIRPPQDVYEAPGADVIFMAELNKDGV---EVKWLRNNMIIIQGDKHQMMSEGKVHRLQV 7207 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 E+K +Y A + + +E+ K V + +V + P + Sbjct: 7208 CEIKPRDQGEYRFIAKDKEARAKLELAAAPRIKTGDQNLVVDVGNPLTMTVPYDAYPRAE 7267 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 L+ E+ P D D T+ I + ++ + ++V+ +N +EA Sbjct: 7268 AEWLKG-----EESLPTTT-----VDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQAEA 7317 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGK 1811 + ++ DVP D E V + W E +GGS II Y VE + + K Sbjct: 7318 FINVEVI-----DVPGPVRNLEVTEIYDGE-VGLAWQEPESDGGSKIIGYVVERRDIKRK 7371 Query: 1812 KWKXXXXXXX----XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 W +QK + Y FR+ ARN +GT P ++ + P Sbjct: 7372 TWIVVTDHAENCEYTVTGLQKGGVE--YLFRVSARNRVGTGEPVETERPVEAKSKFEVPG 7429 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P+N V++ TL W PE +GGSPIT Y+IE + W +T G + Sbjct: 7430 PPQNVEVTDVNRFGRTLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVL 7489 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 ++ E +E FR+ A+N VGV P+ +++V++ PS L+ V + Sbjct: 7490 TDVVENEEYFFRVRAQNMVGVGKPSHPTRAVKITDPIERPS-GNINLDHSDQTKTSVQLT 7548 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P DGG+P+LGY I ++ W+ V F + L +Y R+ A N Sbjct: 7549 WEPPLEDGGSPILGYIIERKEEGTDKWIRCNPKLVPACAFKVTGLKAGSSYYYRVSAENA 7608 Query: 2047 IGLSEPLESDEP 2058 G+S+P E+ P Sbjct: 7609 AGVSDPAEAIGP 7620 Score = 296 bits (727), Expect = 4e-78 Identities = 287/1205 (23%), Positives = 498/1205 (41%), Gaps = 91/1205 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +++L+P G +F + G P+P+++W++ + P + +D TL+ Sbjct: 2966 PQIIQELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEY-TLL 3024 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + E FPED+ +TC AKN G A+++ L VE P E+ V Sbjct: 3025 LIETFPEDSAVYTCEAKNDYGVATTSASLSVEIP-EVVSPELEVPV-------------- 3069 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 PP + EG +CR+ + ++W K EI P + D + Sbjct: 3070 --YPPAVIVPLRDAVTSEGQSARFQCRVTG-TDLKVSWYSKDREIKPSRFFRMTQFEDTY 3126 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP--------- 740 L+I EGTYT VA N G+ + +LK++ EK + +E Sbjct: 3127 Q----LEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVA 3182 Query: 741 ------LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITI 791 L+ + V + +V P W K + + +S ++ I Sbjct: 3183 PILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEI 3242 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTI 850 +P +V D G Y+ KA N G ++A +TV EPP FI + VK+ + Sbjct: 3243 PRP-QVVDCGEYSCKASNQHGSVSSTAFLTV-------TEPPRFIKKLDSSRLVKQHDST 3294 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 + +V +P +TWY+ I PSE + +F L + N+ E DSGDY C A N Sbjct: 3295 RYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVLEMHNLSVE-DSGDYSCEAQN 3353 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS 968 AG +S + + F K +T +G V LEC+ T WY +K+EI Sbjct: 3354 PAGSASTSTSLKVKAPP-AFTKK-PHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIR 3411 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTML--VVKETIPEFIRKLQD 1025 +++ E DVG C V D + + + V P F++KL D Sbjct: 3412 SSKKYKVMSENYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSD 3471 Query: 1026 FEVKEKDVAILEVEI-NSETADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 V + L+ + ++ V+W +D GEII+ +N + ++ L I N + Sbjct: 3472 VTVVVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLW-ISYSENVASLKIGNAEPTN 3530 Query: 1084 EGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VR 1138 G+Y C +++++ C A++TV+E P I+ + KV G+ T E + L R Sbjct: 3531 AGKYICQIKNDAGFQECFAKLTVLE-PAVIVEKPGPVKVTAGDSCTLECTVDGTPELTAR 3589 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEP 1194 WFKDG+E+ + +++ K LKI + L+D+GEY+ E VG S CTA L V + Sbjct: 3590 WFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQVSDR 3649 Query: 1195 SI--NFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 + +FT +L E + A L ++ + V+W+ I +K+ Sbjct: 3650 IMPPSFTRKLKE-TYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTC 3708 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 +L + E D Y+C + + + + V PP V + + G ++T Sbjct: 3709 SLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFVKKPEPFNVLSGENITFTSI 3768 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 + P +W S + ++ A L + V+ +G Y ++ N G Sbjct: 3769 VKGSPPLEVKWFRGSIELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAGKIS 3828 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++ + + K N L ++ I E TG I V +++ S Sbjct: 3829 CTTHLFVKEPAKFVMKVNDLSVEKGKNLIL--ECTYTGTPPI---SVTWKKNGVILKHSE 3883 Query: 1431 K-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 K +IT T+TS NS + ++ +D+ + + + T ++ P PL+ Sbjct: 3884 KCSITTTETSAILEIPNSKLEDQGQYSCHIE-NDSGQDNCHGAI---TILEPPYFVTPLE 3939 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENR-XXXXXXXXXXXXX 1545 + + L C G P+ V+WY+ KL+ T K ++N+ Sbjct: 3940 PVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDS 3999 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEV 1604 Y C N GE +S ++ +Q++ + ++ H+ VG I G P EV Sbjct: 4000 GEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEV 4059 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W+K+ +++ D + + + ++++I + +S +YT ASN GT+S L + + Sbjct: 4060 SWFKDNVRVKEDYNVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTE 4119 Query: 1665 KPSKP 1669 + P Sbjct: 4120 GKTPP 4124 Score = 271 bits (665), Expect = 1e-70 Identities = 279/1206 (23%), Positives = 476/1206 (39%), Gaps = 71/1206 (5%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 ++P P E P + LR T +G + +F+C+V G +++W+ + IKPS Sbjct: 3056 EIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSARFQCRVTGTDL-KVSWYSKDREIKPS 3114 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 + F+M +D L I E +PED GT+T VA N+ G +ST L +EAP ++ Sbjct: 3115 RFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNSVGQVTSTAILKLEAPEKIMYEKLE- 3172 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 ++ + P ++ + V C + P W G E Sbjct: 3173 ----------EEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGRE 3222 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 I + S+ + Y S L+I + G Y+ A N+ G S L + E Sbjct: 3223 IYDGDKYSIRSSN----YLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTVT----E 3274 Query: 734 PPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 PP+ I+ L S +V+Q +S +V G+P +TW K + S S+ +L Sbjct: 3275 PPRFIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVL 3334 Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 + V+D G Y+ +A+N G A TS + V+ P P F + + + + Sbjct: 3335 EMHNLSVEDSGDYSCEAQNPAGSASTSTSLKVKAP-------PAFTKKPHPVQTLKGSDV 3387 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 L + P I+WY++ I S+ + + I NVD+ D G+Y C A N Sbjct: 3388 HLECELQGTPPFQISWYKDKREIRSSKKYKVMSENYLASIHILNVDTA-DVGEYHCKAVN 3446 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEI- 967 G S VT+ TFVK L G+T+ L+ + + +S W +K EI Sbjct: 3447 DVGSDSCIGSVTLRAPP-TFVKKLS-DVTVVVGETIELQAAVEGAQPISVLWLKDKGEII 3504 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQ 1024 ++ I + G C +K+ K T+ E + K Sbjct: 3505 RESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVLEPAVIVEKPG 3564 Query: 1025 DFEVKEKDVAILEVEINSETADVV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 +V D LE ++ T ++ W +DG + +KY + L I N + Sbjct: 3565 PVKVTAGDSCTLECTVDG-TPELTARWFKDGNELSTD-HKYKISFFNKVSGLKILNAGLE 3622 Query: 1083 DEGEYSCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDA- 1135 D GEY+ +++ SCTA + V + +PP +L+ G+ A E ++ Sbjct: 3623 DSGEYTFEVKNSVGKSSCTASLQVSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPI 3682 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV 1191 LV WF DG EI + Q T+ LK+ D G YSC G+ +C+A L+V Sbjct: 3683 LVSWFHDGQEITSGDKYQATLTDNTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSV 3742 Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 EP +F + F ++ + ++ L+V W++ + K + Sbjct: 3743 REPP-SFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQDSVA 3801 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L + +YTC + + + V+ P K V + +++G ++ L Sbjct: 3802 ELELFDVQPLQSGDYTCQVSNEAGKISCTTHLFVKEPAKFVMKVNDLSVEKGKNLILECT 3861 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 Y P + W N I+K + + SA L I + D G Y +EN+ G + Sbjct: 3862 YTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIENDSGQDN 3921 Query: 1371 VEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 +TIL+ P P +P + + S+ C + T + +Y + + T Sbjct: 3922 CHGAITILEPPYFVTPLEPVQVTVGDSASLQC--QVAGTPEMIVSWYKGDTKLRGTA--- 3976 Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 +VK K Q + S Y + +V+ + T+ ++E K+ P+ + L Sbjct: 3977 TVKMHFKNQVATLVFSQVDSDDSGEY-ICKVENTVGEATSSSLLTVQERKLP-PSFTRKL 4034 Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXX 1544 +++ + C G +V+W++D ++K + +N Sbjct: 4035 RDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQILKTDKSL 4094 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPE 1603 Y C A N G +S + + + + I + G+ I G P Sbjct: 4095 MGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIR 4154 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 V W K+ ++ Y I+ E T+ + I + R S KYT ASN G S L V Sbjct: 4155 VTWAKDNQEIRTGGNYQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVK 4214 Query: 1664 DKPSKP 1669 ++ + P Sbjct: 4215 ERKTPP 4220 Score = 264 bits (647), Expect = 2e-68 Identities = 343/1431 (23%), Positives = 565/1431 (39%), Gaps = 118/1431 (8%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+K V+E + L C ++ P ++ W FKG+E VPD I +L Sbjct: 6702 FTKNLHDLEVNENETVRLICE-ISKPNAEVTW-FKGDEEVPDGGRFEYISDGRKR---IL 6756 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I N G YT + L V ++ PQ +E L +G+ + Sbjct: 6757 VIRNAHPEDAGKYTCKLPSSSTTGKLT-VHELAAEFLTRPQNLEVL------EGDKAEFA 6809 Query: 756 AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 V T+ W + +P SDG ++ ++K V D G YT+ G Sbjct: 6810 CSV-SKEAITVQWLWGDTVLEPGDKYDIISDGKKRTL-VVKDSVVGDAGKYTVMV----G 6863 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A+ +A +TV E T++ N ++ V E I V + WY+N E Sbjct: 6864 EAKATARLTVIEKTQD-------YNSLKDQEVNEGQEIIFNCEVNKEGAKE-KWYKNGEA 6915 Query: 873 ISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHG-ARVTIDVEKVTF 930 I S +++ + D+++ D Y SN G+ + A +T+ E + Sbjct: 6916 IFDSAKYI--IVQKDLVYTLRIRDTQLKDQATYSISLSNHRGEHAESSAALTVLEEGLRI 6973 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 V+ L+ ET E KTV C+ + +T KW N +EI+ + R + + + Sbjct: 6974 VEPLE-DIETMEKKTVTFWCKVNRLNATLKWTKNGEEIT-FNKRILYKIDKYKHSLIIKD 7031 Query: 990 -XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048 D G ++ L++ E +FI LQD V E D A+ +++ E A V Sbjct: 7032 CGFKDEGEYTVTAGQDKSVAELLITEAPADFIEHLQDQTVTEFDDAVFTCQLSKEKASVK 7091 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W R+G IK K KY FEK G++ +L I++ + DE EYSC + D A + V E+P E Sbjct: 7092 WYRNGREIKEGK-KYQFEKDGNLHRLIIKDCRLDDECEYSCGVDDRKSRARLFVEEIPVE 7150 Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 II Q+ G F EL K V+W ++ I + Q+ +GK +L++ + Sbjct: 7151 IIRPPQDVYEAPGADVIFMAELNKDGVEVKWLRNNMIIIQGDKHQMMSEGKVHRLQVCEI 7210 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL--- 1225 D GEY + + A L + ++ + LV + LT+ +P + Sbjct: 7211 KPRDQGEYRFIAKDKEARAKLELAAAP---RIKTGDQNLV-VDVGNPLTMTVPYDAYPRA 7266 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283 + W K + + T T+ + T I + + D+ Y VL + A++ + VEV Sbjct: 7267 EAEWLKGEESLPTT---TVDTTTDCTTFKIYEAKKSDKGRYKVVLRNKHAQAEAFINVEV 7323 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQ---AFPQPNDE-------WIVNSKIIKKCKH 1333 ++ P + R +VT + D + A+ +P + ++V + IK+ Sbjct: 7324 IDVPGPV----------RNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVERRDIKRKTW 7373 Query: 1334 TKPSIDSKSASLTIKKVENTDAG-IYKLRLENNCGHAD---VEMNVTILDK---PSPPGK 1386 + +++ T+ ++ ++++ N G + E V K P PP Sbjct: 7374 IVVTDHAENCEYTVTGLQKGGVEYLFRVSARNRVGTGEPVETERPVEAKSKFEVPGPPQN 7433 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLK 1444 + +++ + W+ PE G S I YV+E + + +W + S + ++ Sbjct: 7434 VEVTDVNRFGRTLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVLTDVV 7493 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-------KPLKNITTEPNE 1497 N Y FR A N V + S T K+ + S + K +T EP Sbjct: 7494 ENEEYFFRVRAQNMVGVGKPSHPTRAVKITDPIERPSGNINLDHSDQTKTSVQLTWEPPL 7553 Query: 1498 DIELTCIFGGVPQPKVT----WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + + I G + + K W R KL A A Y+ A Sbjct: 7554 EDGGSPILGYIIERKEEGTDKWIRCNPKLVPACA-------FKVTGLKAGSSYYYRVSAE 7606 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE------GIPPPEVIWY 1607 N G + + +G + + K G E +V I+ G P P W Sbjct: 7607 NAAGVSDPAEAIGPLTADDPFVDLQWPLSAFKDGLEVIVPEPIKIRVPITGYPIPTATWS 7666 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 LE + T + + I +R YT+ N + S E+ + V +PS Sbjct: 7667 FGDQVLEEGGRVTMKTTSTFAELVITPSERPDKGIYTLTLENPVSSVSGEIDVNVLARPS 7726 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 P+ ++ ++SR +V + W+PP DDGG + Y IEK E WIKV D D E + Sbjct: 7727 APKELKVV-DVSRSTVQLSWEPPEDDGGSPVIDYIIEKREVSRKTWIKVMDHVIDQE-FS 7784 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L + EY+FRV A N G E A EPI + VP ++ +++ Sbjct: 7785 VPDLIQGKEYLFRVCACNKCGPGEPAYIDEPINMSAPATVPDPPENVKWRNP-TSKGIFL 7843 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEG-KKWKX-XXXXXXXXARIQKLSINTTYQFRIYARNE 1844 TW P + +GG+ I Y VE Q G KW+ + KL Y +R+ A N Sbjct: 7844 TWEPPKYDGGARIKGYLVEKCQRGTDKWEICGEPVIETKMEVTKLKEGEWYAYRVKALNR 7903 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 IG S P D I P + + + K P G P I Sbjct: 7904 IGASKPSKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKAGTKIELPAKITGKP-EPQITWT 7962 Query: 1905 KTVKGKSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 K K +T+ + + I + K D + I A N+ G + +V L+K Sbjct: 7963 KAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYIIEAVNSSGRATAVVEVNV-LDK- 8020 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 P PP A ++ + + + +W P DGG+ + Y + R +W Sbjct: 8021 ---PGPPAA-FDVSEITNESCLLTWNPPRDDGGSKITNYVLEKRATDSEIW 8067 Score = 234 bits (573), Expect = 2e-59 Identities = 244/1068 (22%), Positives = 431/1068 (40%), Gaps = 62/1068 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F+KKP +GSD+ LEC L P I+W EI + V E+ Y Sbjct: 3369 PPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSEN----YL 3424 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + + I NV G Y AVN G S + ++ PP ++ L + V GE++ Sbjct: 3425 ASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRA----PPTFVKKLSDVTVVVGETI 3480 Query: 753 ILSAQVVGNPRPTITWCKN-NKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809 L A V G ++ W K+ + ++ + ++ LK + + G Y + +N Sbjct: 3481 ELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKN 3540 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G E A +TV EP + + + + V + L V P + W+++ Sbjct: 3541 DAGFQECFAKLTV-------LEPAVIVEKPGPVKVTAGDSCTLECTVDGTPELTARWFKD 3593 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID--VEK 927 +S +F + L I N E DSG+Y NS GKSS A + + + Sbjct: 3594 GNELSTDHKYKISFFNKVSGLKILNAGLE-DSGEYTFEVKNSVGKSSCTASLQVSDRIMP 3652 Query: 928 VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 +F + L+++Y + G + +LEC+ S + W+H+ +EI+ D + Sbjct: 3653 PSFTRKLKETY-GQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNTCSLK 3711 Query: 986 XXXXXXXDVGVIKC----IVKDQETSTMLVVKETIPEFIRKLQDFEV-KEKDVAILEVEI 1040 D+G C + E S L V+E P F++K + F V +++ + Sbjct: 3712 VNGLQESDMGTYSCTATNVAGSDECSAFLSVREP-PSFVKKPEPFNVLSGENITFTSIVK 3770 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SC 1096 S +V W R G I +K + + + +L + + G+Y+C + +E SC Sbjct: 3771 GSPPLEVKWFR-GSIELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQVSNEAGKISC 3829 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 T + V E P + + ++ + V KG E T + V W K+G ++ S +T Sbjct: 3830 TTHLFVKE-PAKFVMKVNDLSVEKGKNLILECTYTGTPPISVTWKKNGVILKHSEKCSIT 3888 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 L+I + L+D G+YSC + G C +T+ EP T P + V + Sbjct: 3889 TTETSAILEIPNSKLEDQGQYSCHIENDSGQDNCHGAITILEPPYFVTPLEPVQVTVGDS 3948 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC--- 1268 V E + V+WYK + + T + + TL+ + DD EY C Sbjct: 3949 ASLQCQVAGTPEMI-VSWYKGDTKLRGTATVKMHFKNQVATLVFSQVDSDDSGEYICKVE 4007 Query: 1269 -VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + +A S++ L V+ + PP R+ G VT W ++ Sbjct: 4008 NTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGIAGSEPIEVSWFKDNVR 4067 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GK 1386 +K+ + S A L I K + + G Y N G A + + + +PP Sbjct: 4068 VKEDYNVHTSFIDNVAILQILKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFD 4127 Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLK 1444 I +D E +G I + + + QEI T + + T +I + Sbjct: 4128 TPITPVDGIIGESADFECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAHLTILRVD 4187 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT--TEPNEDIELT 1502 S ++ YA NEV + +KE K PT + L TE NE ++L Sbjct: 4188 RGDSGKYTCYASNEVGKDSCTAQLN----VKERK-TPPTFTRKLSEAVEETEGNE-LKLE 4241 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTA---KATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGE 1558 G V+WY++ +++ ++ + +++N Y C N+ G Sbjct: 4242 GRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGS 4301 Query: 1559 VETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 V + V I++ + ++ ++ + GD ++ + G P + W K G ++ + Sbjct: 4302 VLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASE 4361 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + + +++ + + +S S +Y +ASN AGT + + V +K Sbjct: 4362 RCSFSFANGVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKEK 4409 Score = 214 bits (523), Expect = 2e-53 Identities = 240/1082 (22%), Positives = 435/1082 (40%), Gaps = 76/1082 (7%) Query: 639 KPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 KP A V E + EC VA PE + WL G+ + + + L I Sbjct: 2351 KPLADLTVAESQRAVFECE-VANPESEGQWLKNGKPLPMTDQYRAETDGVKRR----LNI 2405 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 K G Y+ + + A L + E ++ + LK++ V + + + S + Sbjct: 2406 PAAKMDDMGEYSYEIASSKTSAKLHV---------EAVKIKKTLKNLTVTETQEAVFSVE 2456 Query: 758 VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 + W KN +++ G H++ I K V DE VY+ K G Sbjct: 2457 LSHPDVKGALWIKNGVELESNDKYEISVKGTVHTLKI-KHCVVTDESVYSFKL----GKI 2511 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 +A + VE I + +++T E + V+ + VP + W+ N + Sbjct: 2512 GANARLHVETVK--------IIKKPKDVTALENAVVSFELSVSHDTVP-VRWFHKNVELK 2562 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 S+ + +L++ N+ S D+G+Y K+ + VE + K + Sbjct: 2563 QSDKYKMISQRKVHKLMLHNI-SPADAGEYTAFVGQLECKAK------LFVETIHITKTM 2615 Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 KS E E KT +C+ SH V + W N EI + +I+ +G+ D Sbjct: 2616 -KSIEIPETKTASFQCEVSHFNVPSVWLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSSED 2674 Query: 994 VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053 + + S L VK + L+D +EKD EV +N E W ++G Sbjct: 2675 SAEYTFVCGNDRVSATLTVKPIL--ITSMLEDINAEEKDTITFEVTVNYEGISYKWLKNG 2732 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRL 1113 IK +K + L IRN D EYS + + +A + V E + Sbjct: 2733 VEIK-STDKCQIRTKKLTHSLSIRNVHFGDAAEYSFVAGKAASSATLYVEARHIEFRKHI 2791 Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 ++ KV + +A FE E+++ D V+W KDG E+Q + +++ + +L I + DA Sbjct: 2792 KDIKVVEKKRAIFECEISEPDVQVQWMKDGQELQIGDRMKIQREKYVHRLIIPSTKMSDA 2851 Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 G+Y+ G + +A L VE + + + I V A + E+ ++ ++ WYK Sbjct: 2852 GQYTVVAGGNTSSANLIVEGRDVRIR-SIRKEIQVIERQRAEIEFEVNEDDIEPQWYKDG 2910 Query: 1234 SVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 I E+++ + + + + I + T D EYT V +S+ L V E PP+I+ Sbjct: 2911 IEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGRNRSSVVLYVNAPE-PPQII 2969 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + ++ G PQP W + + + K D++ +L + + Sbjct: 2970 QELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETF 3029 Query: 1352 NTDAGIYKLRLENNCGHA--DVEMNVTILDKPSP----PGKPNILEID-----SSSINIC 1400 D+ +Y +N+ G A ++V I + SP P P + + +S Sbjct: 3030 PEDSAVYTCEAKNDYGVATTSASLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSA 3089 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNL--KTNSSYRFRA-YAV 1456 + TG + + + +EI + + + T Q I + +Y F A +V Sbjct: 3090 RFQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSV 3149 Query: 1457 NEVDIS-----DASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTCIFGGV 1508 +V + +A E Y K+ +E +++ +P + + L+ + N + TC Sbjct: 3150 GQVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETT 3209 Query: 1509 PQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 P K WY+ G+++ K + + Y C A N HG V ++ Sbjct: 3210 PNVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAF 3269 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + + + P I D + K D + G P +V WYK ++ ++Y+++ Sbjct: 3270 LTVTEPPRF-IKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGETEIHPSEKYSMSFV 3328 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 + +V+ + L S Y+ EA N AG++S +LKV P+ + P ++ + V Sbjct: 3329 DSVAVLEMHNLSVEDSGDYSCEAQNPAGSASTSTSLKVKAPPAFTKKPHPVQTLKGSDVH 3388 Query: 1685 IE 1686 +E Sbjct: 3389 LE 3390 Score = 204 bits (498), Expect = 2e-50 Identities = 240/1119 (21%), Positives = 441/1119 (39%), Gaps = 91/1119 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KKP+ V G +I + P ++ W E+ P ++ ++ + Sbjct: 3745 PPSFVKKPEPFNVLSGENITFTSIVKGSPPLEVKWFRGSIELAPGHKCNITLQDSV---- 3800 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L++ +V+ Q G YT N G+ S L +K EP + + + + V +G+++ Sbjct: 3801 AELELFDVQPLQSGDYTCQVSNEAGKISCTTHLFVK----EPAKFVMKVNDLSVEKGKNL 3856 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810 IL G P ++TW KN +K S T + IL+ K++D+G Y+ EN Sbjct: 3857 ILECTYTGTPPISVTWKKNGVILKHSEKCSITTTETSAILEIPNSKLEDQGQYSCHIEND 3916 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G IT+ EPP F+ + + V + L +V P ++WY+ + Sbjct: 3917 SGQDNCHGAITI-------LEPPYFVTPLEPVQVTVGDSASLQCQVAGTPEMIVSWYKGD 3969 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-- 928 + + T+ +F + LV + VDS+ DSG+Y C N+ G+++ + +T+ K+ Sbjct: 3970 TKLRGTATVKMHFKNQVATLVFSQVDSD-DSGEYICKVENTVGEATSSSLLTVQERKLPP 4028 Query: 929 TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 +F + L+ +ET G V +C S + W+ + + + Sbjct: 4029 SFTRKLRDVHETV-GLPVTFDCGIAGSEPIEVSWFKDNVRVKEDYNVHTSFIDNVAILQI 4087 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040 +G C + +S LV+ E T P F + + + A E I Sbjct: 4088 LKTDKSLMGQYTCTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHI 4147 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 + ++ V W +D + I+ N Y + L I D G+Y+C +E S Sbjct: 4148 SGTQPIRVTWAKDNQEIRTGGN-YQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDS 4206 Query: 1096 CTAEVTVVELP-PEIITRLQNQKVNK--GNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151 CTA++ V E P TR ++ V + GN+ E + L V W+K+ E+ S H Sbjct: 4207 CTAQLNVKERKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPH 4266 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFIL 1207 +++ L I DAG Y+C+V N CT+ + + EP P L Sbjct: 4267 CEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQP---L 4323 Query: 1208 VPANTDAYLTVEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 PA T+ T+++ E + + W K I +E+ + L + T+ D Sbjct: 4324 QPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSD 4383 Query: 1263 QCEYTCVLLD--------AKSTTKLKVEVVEFPPK--------IVDYEREYRIKRGSDVT 1306 EY C + +K T K K +V K V + ++ + T Sbjct: 4384 SGEYVCKASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVAT 4443 Query: 1307 LLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 + P PN +W+ + + + A L IK TD+G+YK N Sbjct: 4444 FIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTTKTDSGLYKCVAFNQ 4503 Query: 1366 CGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYV--VEYQEI 1422 G + +N+ + ++ + ++ ++ DE + ++ V EY++ Sbjct: 4504 HGEIERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDILELLKNVDPKEYEKY 4563 Query: 1423 DTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKI 1479 I+ + + + ++ + S+R + D E E I++ T+ Sbjct: 4564 ARMYGITDFRGLLQAFELLKQTREEESHRLEIELTEKAQKED-QEFEELVAFIQQRLTQT 4622 Query: 1480 QSPTVEKPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538 + T+ + ++N T +ED C I P+ K++WY+ +KL ++ Y+ + Sbjct: 4623 EPVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLDSSD-KYKIK------ 4675 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTA 1594 K D G C I + I + H K G+ ++ Sbjct: 4676 IEGDRHILKIKNCQLEDQGNYRIVCGPHIASARLTVIEPAVERHLHDTTFKEGNTCTLSC 4735 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 IP + WY+NG ++ Y+ +K + IK+++ +YT + N T+ Sbjct: 4736 QF-SIPNAKSQWYRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLDNLETTA 4794 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 + + + + V+ +S T E + DD Sbjct: 4795 DLTIEAEPIQFTKSIQNIVVS---EHQSATFECEVSFDD 4830 Score = 183 bits (446), Expect = 4e-44 Identities = 171/703 (24%), Positives = 311/703 (44%), Gaps = 56/703 (7%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPTF++K +A EG+++ LE R+ ++W +E+ + ++ +++ + Sbjct: 4219 PPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLL- 4277 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L I +V + G YT N G + I+ K+PP +PL+ +G++ Sbjct: 4278 ---LHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIRE-PKKPPVFDQPLQPAATEEGDT 4333 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809 + LS V G+ I W K + ++A S + + +L+ V D G Y KA N Sbjct: 4334 LQLSCHVRGSEPIRIQWLKAGREIRASERCSFSFANGVALLELAAVTKSDSGEYVCKASN 4393 Query: 810 SEGIAETSAVITVEEPT-------EENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPV 861 G + +TV+E + + E L F++ Q I V EK +A+V +P+ Sbjct: 4394 VAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVSEPQSIKVMEKTVATFIAKVGGDPI 4453 Query: 862 PSITWYRNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P++ W + ++ I Q G+ +L I + ++ DSG YKCVA N G+ Sbjct: 4454 PNVKWMKGKWRQLNQGGRIIIQQ-RGDEAKLEIKDT-TKTDSGLYKCVAFNQHGEIERSV 4511 Query: 920 RVTIDVEKVTFV--------KHLQKSYETEEGKTV-ILECQTSHTVSTKWYHNKKEISGM 970 + ++ K V K + + +E +T+ ILE + V K Y + G+ Sbjct: 4512 NLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDILELLKN--VDPKEYEKYARMYGI 4569 Query: 971 -DHREIIQEGRXXXXXXXXXXXX-DVGVI-KCIVKDQETSTMLV-----VKETIP-EFIR 1021 D R ++Q ++ + K +DQE ++ + +T P IR Sbjct: 4570 TDFRGLLQAFELLKQTREEESHRLEIELTEKAQKEDQEFEELVAFIQQRLTQTEPVTLIR 4629 Query: 1022 KLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 +++ V + AI E EI N + W + + + +KY + G L I+N Sbjct: 4630 DIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKLD-SSDKYKIKIEGDRHILKIKNC 4688 Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRW 1139 + D+G Y + +A +TV+E P + L + +GN T + + +A +W Sbjct: 4689 QLEDQGNYRIVCGPHIASARLTVIE--PAVERHLHDTTFKEGNTCTLSCQFSIPNAKSQW 4746 Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199 +++G I+ + K KL I D +D G+Y+C++ N + TA LT+E I FT Sbjct: 4747 YRNGRPIKIGGRYSTQVSDKVHKLIIKDVRTEDQGQYTCKLDNLETTADLTIEAEPIQFT 4806 Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 + + I+V + A E+ + VTWYK + + ++ K++ S+ + + I T Sbjct: 4807 KSI-QNIVVSEHQSATFECEVSFDDAVVTWYKGPTELTESPKYSFRSEGRCHYMTIHNVT 4865 Query: 1260 EDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292 +D+ Y+ + +A+ST +L + E PP + D Sbjct: 4866 AEDEGVYSVIARLEPRGEARSTAELYLVTKEIKLELKPPDVPD 4908 Score = 182 bits (443), Expect = 1e-43 Identities = 228/1007 (22%), Positives = 389/1007 (38%), Gaps = 83/1007 (8%) Query: 660 IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 I E DI W KGE + P + E L + VK Q G A+N Sbjct: 5657 ISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRF----LTLHKVKLEQAGEVLYQALN--- 5709 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 A +L +K E + PLK + V + + V + W K +K Sbjct: 5710 -AVTTAILTVKEIELD---FAVPLKDVTVPEKRQARF--ECVLTREANVIWSKGTDILKI 5763 Query: 778 ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 +DG H I ++ + DEG YT + E + A + VE + Sbjct: 5764 GEKFDIIADGKKH-ILVINDSQFDDEGEYTAEVEGKKSTAR----LFVEGVRLK------ 5812 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 FI Q+ TVKE T ++ + + WY+N++ + S T+ +G+ +L + Sbjct: 5813 FITPLQDQTVKEGETAYFQFELSHEGM-LVKWYKNDKRLHTSRTVFITSEGKVHKLEMRE 5871 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 V + D + K V + ++ ++ + VK LQ Y E + L+C+ S Sbjct: 5872 VTLD-DISEIKAVVKDM---NTQANLKVLEADPYFTVK-LQ-DYSALEKDDITLQCELSK 5925 Query: 955 TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014 V KWY + +E+ I +G D GV +C +T+ + V+ Sbjct: 5926 DVPVKWYKDGEELVASSRISIKTDGLRRILTIKKATEGDKGVYECSCGTDKTNCNIGVEP 5985 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 + + R L EV + A E+EI+ +W+ GE + P + + + G L Sbjct: 5986 RLIKVERPLYGVEVFVGETARFEIEISEPDVHPIWKLKGETLTPSP-ECEIIEDGKKHIL 6044 Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134 + + GE S + A + V ELP IT L + KV + ++A FE E+++ Sbjct: 6045 ILHQGRLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREP 6104 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 RW K EI ++ DG K L I DD +Y E + + +A L +E Sbjct: 6105 KTFRWLKGTQEITPDERFEIISDGTKHALIIKSVAFDDEAKYMFEAEDKRTSAKLIIEGI 6164 Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 + F L + T A TVE+ E + V W+K + ++ ++ D K TL Sbjct: 6165 RLKFITPLKDVTKKERET-AVFTVELSHENIPVVWFKNDQRLHTSKVVSMTDDGKFHTLT 6223 Query: 1255 IRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314 I+ T DD + + S KL V+E P ++Y +V L + Sbjct: 6224 IKDLTIDDTSQIRVEAMGKSSEAKL--TVLEGDPYFTGKLQDYTAVEKDEVILQCEISKA 6281 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P +W+ + K I K+ D K L +KK D G Y +CG N Sbjct: 6282 DAP-VKWMKDGKPITPSKNVVIKADGKKRILILKKALKKDIGQYTC----DCGTDQTSAN 6336 Query: 1375 VTILDKPSPPGKP----NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + I D+ +P ++E +++ +I E GN + ++ + + + + Sbjct: 6337 LNIEDRDIEIIRPLYSVEVIETETARFDIEISEEGVHGN-----WKLKGEPLTESPDCEI 6391 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 K K + Y R VD A+ + + +K I + +PLK+ Sbjct: 6392 KEEGKKHFL-------TLYNVRLDQAGGVDFQAANAKSGAHLRVKPRVI---GLLRPLKD 6441 Query: 1491 ITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY 1548 +T E C + G+P V WY GKKL E Sbjct: 6442 VTVTAGESATFDCELSYEGIP---VEWYLQGKKL-------EPSDKVVTRAEGRAHTLIL 6491 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL---VTAVIE---GIPPP 1602 + + D GEV + + + + + ++ + D+ + TA++E Sbjct: 6492 RDVKLTDAGEVSLT-AKDFRTQANLFVKEPPVEFTKPLEDQTVEEEATAILECEVSRENA 6550 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 +V W+KNG ++ K+Y+I ++ + + I + YT +A + Sbjct: 6551 KVKWFKNGEEIHKTKKYDIISEGRVRKLIIHGCTLDDAKTYTCDAKD 6597 Score = 181 bits (441), Expect = 2e-43 Identities = 190/781 (24%), Positives = 321/781 (41%), Gaps = 54/781 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+F++K K Y GS +LEC++ P ++W G+EI + + + Sbjct: 3651 MPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTDNT--- 3707 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 CS LK+ +++ GTY+ A N G L + +EPP ++ + V GE+ Sbjct: 3708 CS-LKVNGLQESDMGTYSCTATNVAGSDECSAFLSV----REPPSFVKKPEPFNVLSGEN 3762 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKKVK--DEGVYTLKA 807 + ++ V G+P + W + + ++ P T S+ L+ V+ G YT + Sbjct: 3763 ITFTSIVKGSPPLEVKWFRGS--IELAPGHKCNITLQDSVAELELFDVQPLQSGDYTCQV 3820 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G + + V+EP + F+ + +++V++ + L T P S+TW Sbjct: 3821 SNEAGKISCTTHLFVKEPAK-------FVMKVNDLSVEKGKNLILECTYTGTPPISVTWK 3873 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS-HGARVTIDVE 926 +N I+ SE + + L I N E D G Y C N +G+ + HGA +TI +E Sbjct: 3874 KNGVILKHSEKCSITTTETSAILEIPNSKLE-DQGQYSCHIENDSGQDNCHGA-ITI-LE 3930 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 FV L+ + G + L+CQ + T + WY ++ G ++ + + Sbjct: 3931 PPYFVTPLE-PVQVTVGDSASLQCQVAGTPEMIVSWYKGDTKLRGTATVKMHFKNQVATL 3989 Query: 985 XXXXXXXXDVGVIKCIVK----DQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEV 1038 D G C V+ + +S++L V+E P F RKL+D + Sbjct: 3990 VFSQVDSDDSGEYICKVENTVGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDC 4049 Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 I SE +V W +D +K N + ++ L I T G+Y+C + T Sbjct: 4050 GIAGSEPIEVSWFKDNVRVKEDYNVHT-SFIDNVAILQILKTDKSLMGQYTCTASNAIGT 4108 Query: 1098 AE------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 A +T + PP T + G A FE ++ + V W KD EI+ Sbjct: 4109 ASSSGKLVLTEGKTPPFFDTPITPVDGIIGESADFECHISGTQPIRVTWAKDNQEIRTGG 4168 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLPE 1204 + Q++ L I D D+G+Y+C EVG CTA L V+E FT +L E Sbjct: 4169 NYQISYVENTAHLTILRVDRGDSGKYTCYASNEVGKDSCTAQLNVKERKTPPTFTRKLSE 4228 Query: 1205 FILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + + L + + L V+WYK + + + L I+ + D Sbjct: 4229 AVEETEGNELKLEGRVAGSQPLTVSWYKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDA 4288 Query: 1264 CEYTC-VLLDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQP-ND 1319 YTC V +A S V+ P P + D + D L + +P Sbjct: 4289 GLYTCKVSNEAGSVLCTSSVVIREPKKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRI 4348 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +W+ + I+ + S + A L + V +D+G Y + N G VT+ + Sbjct: 4349 QWLKAGREIRASERCSFSFANGVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKE 4408 Query: 1380 K 1380 K Sbjct: 4409 K 4409 Score = 178 bits (434), Expect = 1e-42 Identities = 241/1074 (22%), Positives = 432/1074 (40%), Gaps = 81/1074 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P ++ ++Q V +G+D R+V P+P+ W G +I + I D C Sbjct: 1805 PKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWYWPEDN--VCE 1862 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 ++ I +V + V AVN GE S L ++ K+ I+ L+ ++ ++ +S+ Sbjct: 1863 LV-IRDVTADDSASIMVKAVNIAGETSSHAFLLVQA--KQLISFIQNLQDVVAKERDSMA 1919 Query: 754 LSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 P + W KN + + SD H +++L + + D Y+ Sbjct: 1920 TFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVE-MSDADDYSCALVED 1978 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 E + +T+A + VE E FI +++ V E T +L V+ + WY + Sbjct: 1979 ESV-KTTAKLIVEGAVVE------FIKELEDVEVPESFTGELECEVSPEDIEG-KWYHGD 2030 Query: 871 -EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 E+ S + + + G I L I +V+ + D G+Y V GK +H ++ + +T Sbjct: 2031 VELSSNHKYVLASRRGRRI-LTIKDVNKD-DQGEYSFVVD---GKRTH-CKLKMKPRPMT 2084 Query: 930 FVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 ++ L + EG V LE + S V W + EI D I+ + + Sbjct: 2085 ILQGLTDQ-KVCEGDIVQLEVKVSVENVEGVWMKDGHEIQSSDRIHIVLDKQSHMLLIED 2143 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047 D G + E ST V E I L+D V E AILE ++++ + Sbjct: 2144 ATQEDSGTYSFSIPGLELSTTGQVTVYSVEIIVPLKDVHVVEGTKAILECKVSAPDVTSS 2203 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W + IKP + + +G ++L I T DEG Y ++ + VTV E+ Sbjct: 2204 KWYLNDHQIKPDE-RVQAVCKGTKQRLVITRTHASDEGHYKLMVGKVETSCNVTVEEI-- 2260 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 EII L + + +FE+EL+ V W G EI+ ++ GK KL + Sbjct: 2261 EIIRGLHDITCTETQNVSFEVELSHSGIDVIWHFKGQEIKAGPKYKIEARGKIYKLTVVK 2320 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 DD GEY G K + L V +I+ L + V + A E+ + + Sbjct: 2321 MMKDDEGEYVFYAGGKKTSGKLIVAGGAISKPL---ADLTVAESQRAVFECEVANPESEG 2377 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287 W K + T+++ +D KR L I DD EY+ + +K++ KL VE V Sbjct: 2378 QWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEYSYEIASSKTSAKLHVEAV--- 2434 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 KI + + + V+ WI N ++ + S+ +L I Sbjct: 2435 -KIKKTLKNLTVTETQEAVFSVELSHPDVKGALWIKNGVELESNDKYEISVKGTVHTLKI 2493 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 K TD +Y +L +A + + V I+ KP ++ ++++ ++ + Sbjct: 2494 KHCVVTDESVYSFKLGKIGANARLHVETVKIIKKPK-----DVTALENAVVSFELSVSHD 2548 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 T + VE ++ D + IS + + K + N+ + + A+ V +++ Sbjct: 2549 TVPVRWFHKNVELKQSDKYKMISQRKVHKLM--LHNISPADAGEYTAF-VGQLECK---- 2601 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA- 1525 K+ ET + K +K+I + C P V W ++G +++ + Sbjct: 2602 ----AKLFVET----IHITKTMKSIEIPETKTASFQCEVSHFNVPSV-WLKNGVEIEMSE 2652 Query: 1526 --KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIK 1581 K + + Y + ND V + V KP+ IT EDI Sbjct: 2653 KFKIVVQGKLHQLNIMNTSSEDSAEYTFVCGND--RVSATLTV----KPILITSMLEDIN 2706 Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 + K + VT EGI W KNG ++++ + I TK+ T + I+ + ++ Sbjct: 2707 AEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQIRTKKLTHSLSIRNVHFGDAA 2763 Query: 1642 KYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEW 1687 +Y+ A A ++++ V + + K + + + EIS V ++W Sbjct: 2764 EYSFVAGKAASSATLYVEARHIEFRKHIKDIKVVEKKRAIFECEISEPDVQVQW 2817 Score = 177 bits (432), Expect = 2e-42 Identities = 224/998 (22%), Positives = 415/998 (41%), Gaps = 69/998 (6%) Query: 695 LKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751 L I +V+ G YT V N+E ++ +++ E+ P + ++ L+ + V +G+ Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIV-----EELPVRFVKTLEEEVTVVKGQP 5467 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLKA 807 + L+ ++ N ++ W ++ K +K P K G +HS+TI D G YT+ Sbjct: 5468 LYLTCEL--NKERSVVWRRDGKIIKDKPGKFALGIIGLSHSLTITDSDD-SDAGTYTVTV 5524 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 E+SE ++ +S V VE + +P ++ VK KGT + ++ P+I W+ Sbjct: 5525 EDSE-LSCSSCVKVVEVIRDWLVKP------IRDQHVKPKGTATFTCDIVKD-TPNIKWF 5576 Query: 868 RNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 + +E I P++ +G I L I N D G+Y + A++T+ Sbjct: 5577 KGDEEIPAEPTDKTEILKEGNKIFLKIKNA-GPADIGEYSVEVEGRR----YPAKLTLGE 5631 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 +V +K L+ E +T + + S + +W + + EI EG Sbjct: 5632 REVELLKPLE-DVTVYEKETANFDTEISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRFL 5690 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 G + + T+ +L VKE +F L+D V EK A E + E Sbjct: 5691 TLHKVKLEQAGEVLYQALNAVTTAILTVKEIELDFAVPLKDVTVPEKRQARFECVLTRE- 5749 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A+V+W + +I+K + K+D G L I ++ DEGEY+ + + TA + V Sbjct: 5750 ANVIWSKGTDILKIGE-KFDIIADGKKHILVINDSQFDDEGEYTAEVEGKKSTARLFVEG 5808 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 + + IT LQ+Q V +G A F+ EL+ LV+W+K+ + S + +T +GK KL+ Sbjct: 5809 VRLKFITPLQDQTVKEGETAYFQFELSHEGMLVKWYKNDKRLHTSRTVFITSEGKVHKLE 5868 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 + + LDD E V + A L V E FT++L ++ + + D L E+ + Sbjct: 5869 MREVTLDDISEIKAVVKDMNTQANLKVLEADPYFTVKLQDYSALEKD-DITLQCEL-SKD 5926 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 + V WYK + + + ++ +D +R L I+K TE D+ Y C K+ + VE Sbjct: 5927 VPVKWYKDGEELVASSRISIKTDGLRRILTIKKATEGDKGVYECSCGTDKTNCNIGVE-- 5984 Query: 1285 EFPPKIVDYERE-YRIKRGSDVTLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 P+++ ER Y ++ T + + + P + W + + + + D K Sbjct: 5985 ---PRLIKVERPLYGVEVFVGETARFEIEISEPDVHPIWKLKGETLTPSPECEIIEDGKK 6041 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L + + G + N A++++ L +P + E D + Sbjct: 6042 HILILHQGRLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKF----- 6096 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 E E + ++ QEI E + + TK I+++ + ++ A Sbjct: 6097 ECEVSREPKTFRWLKGTQEITPDERFEIISDGTKHALIIKSVAFDDEAKYMFEA------ 6150 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + T +I+ +++ T PLK++T + E T P V W+++ ++ Sbjct: 6151 --EDKRTSAKLIIEGIRLKFIT---PLKDVTKKERETAVFTVELSHENIP-VVWFKNDQR 6204 Query: 1522 LKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 L T+K + + I G+ + + ++ P T +D Sbjct: 6205 LHTSKVVSMTDDGKFHTLTIKDLTIDDTSQIRVEAMGKSSEAKLTVLEGDPYFTGKLQDY 6264 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 K DE ++ I P V W K+G + K I K ++ +K+ + Sbjct: 6265 TAVEK--DEVILQCEISKADAP-VKWMKDGKPITPSKNVVIKADGKKRILILKKALKKDI 6321 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 +YT + GT L + D+ + P+ E+ Sbjct: 6322 GQYTCD----CGTDQTSANLNIEDRDIEIIRPLYSVEV 6355 Score = 176 bits (429), Expect = 5e-42 Identities = 219/964 (22%), Positives = 386/964 (40%), Gaps = 66/964 (6%) Query: 712 AVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 A+ EG+ ++P K + E P++ E ++S V QG +VVG P P W Sbjct: 1779 ALPPEGKITIPTFKPEKVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQW 1838 Query: 769 CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 +N ++ + D +++ D +KA N G + A + V+ Sbjct: 1839 FRNGVQIERTDRIYWYWPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQA- 1897 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 + FI Q++ KE+ ++ T P + W++N I E + D Sbjct: 1898 ----KQLISFIQNLQDVVAKERDSMATFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDR 1953 Query: 886 ENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 + L + V+ D+ DY C + + + K++ A++ ++ V F+K L+ E E Sbjct: 1954 KAHFLSVLAVEMS-DADDYSCALVEDESVKTT--AKLIVEGAVVEFIKELE-DVEVPESF 2009 Query: 945 TVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGR-XXXXXXXXXXXXDVGVIKCIVK 1002 T LEC+ S + KWYH E+S +H+ ++ R D G +V Sbjct: 2010 TGELECEVSPEDIEGKWYHGDVELSS-NHKYVLASRRGRRILTIKDVNKDDQGEYSFVVD 2068 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG-EIIKPKKN 1061 + T L +K ++ L D +V E D+ LEV+++ E + VW +DG EI + Sbjct: 2069 GKRTHCKLKMKPRPMTILQGLTDQKVCEGDIVQLEVKVSVENVEGVWMKDGHEIQSSDRI 2128 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCIL--RDESCTAEVTVVELPPEIITRLQNQKVN 1119 +K+ H+ L I + + D G YS + + S T +VTV + EII L++ V Sbjct: 2129 HIVLDKQSHM--LLIEDATQEDSGTYSFSIPGLELSTTGQVTVYSV--EIIVPLKDVHVV 2184 Query: 1120 KGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 +G KA E +++ D +W+ + +I+ +Q G KQ+L I D G Y Sbjct: 2185 EGTKAILECKVSAPDVTSSKWYLNDHQIKPDERVQAVCKGTKQRLVITRTHASDEGHYKL 2244 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 VG + + +TVEE I +R I + VE+ +DV W+ K I+ Sbjct: 2245 MVGKVETSCNVTVEEIEI---IRGLHDITCTETQNVSFEVELSHSGIDVIWHFKGQEIKA 2301 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298 K+ + + K L + K +DD+ EY K++ KL V + D Sbjct: 2302 GPKYKIEARGKIYKLTVVKMMKDDEGEYVFYAGGKKTSGKLIVAGGAISKPLADL----- 2356 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 S + A P+ +W+ N K + + D L I + D G Y Sbjct: 2357 TVAESQRAVFECEVANPESEGQWLKNGKPLPMTDQYRAETDGVKRRLNIPAAKMDDMGEY 2416 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + ++ A + + + K + E + ++ P+ G + I VE Sbjct: 2417 SYEIASSKTSAKLHVEAVKIKKTLK--NLTVTETQEAVFSVELSHPDVKG-ALWIKNGVE 2473 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSS-YRFRAYAVNEVDISDASETTEYYKVIKET 1477 + D E ISVK T + T+ S Y F+ + ++A E K+IK+ Sbjct: 2474 LESNDKYE-ISVKGTVHTLKIKHCVVTDESVYSFKLGKIG----ANARLHVETVKIIKK- 2527 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXX 1535 P L+N EL+ VP V W+ +LK + R Sbjct: 2528 ----PKDVTALENAVV----SFELSVSHDTVP---VRWFHKNVELKQSDKYKMISQRKVH 2576 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTA 1594 + AF G++E + ++ + T+ + +I + + V+ Sbjct: 2577 KLMLHNISPADAGEYTAF--VGQLECKAKLFVETIHITKTMKSIEIPETKTASFQCEVSH 2634 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 +P +W KNG ++E +++ I + K + I S++YT N ++ Sbjct: 2635 F--NVPS---VWLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSSEDSAEYTFVCGNDRVSA 2689 Query: 1655 SVEV 1658 ++ V Sbjct: 2690 TLTV 2693 Score = 173 bits (420), Expect = 6e-41 Identities = 257/1174 (21%), Positives = 453/1174 (38%), Gaps = 112/1174 (9%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 KKPK E + + E + P + W K E+ + + + +H L + Sbjct: 2526 KKPKDVTALENAVVSFELSVSHDTVP-VRWFHKNVELKQSDKYKMISQRKVHK----LML 2580 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 N+ G YT E +A L + E + + +KS+ + + ++ + Sbjct: 2581 HNISPADAGEYTAFVGQLECKAKLFV---------ETIHITKTMKSIEIPETKTASFQCE 2631 Query: 758 VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V P++ W KN ++ G H + I+ +D YT N Sbjct: 2632 VSHFNVPSV-WLKNGVEIEMSEKFKIVVQGKLHQLNIMNTSS-EDSAEYTFVCGNDR--- 2686 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 SA +TV+ P L + ++I +EK TI V + S W +N I Sbjct: 2687 -VSATLTVK--------PILITSMLEDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIK 2736 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 ++ L I NV D+ +Y VA GK++ A + ++ + F KH+ Sbjct: 2737 STDKCQIRTKKLTHSLSIRNVHFG-DAAEYSFVA----GKAASSATLYVEARHIEFRKHI 2791 Query: 935 QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 K + E K I EC+ S V +W + +E+ D +I +E D Sbjct: 2792 -KDIKVVEKKRAIFECEISEPDVQVQWMKDGQELQIGDRMKIQREKYVHRLIIPSTKMSD 2850 Query: 994 VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053 G + +S L+V+ ++ +V E+ A +E E+N + + W +DG Sbjct: 2851 AGQYTVVAGGNTSSANLIVEGRDVRIRSIRKEIQVIERQRAEIEFEVNEDDIEPQWYKDG 2910 Query: 1054 -EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPEIIT 1111 EI + +Y + I ++ I T+ D GEY+ + R+ S PP+II Sbjct: 2911 IEINFHYEERYSYVVERRIHRMSIFETTYSDAGEYTFVAGRNRSSVVLYVNAPEPPQIIQ 2970 Query: 1112 RLQNQKVNKGNKATF-EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 LQ V G A F I K V W+KD ++ + D ++ L + + Sbjct: 2971 ELQPTTVESGKPARFCAIISGKPQPKVSWYKDDQQLSPGFKCKFLHDAQEYTLLLIETFP 3030 Query: 1171 DDAGEYSCEVGN----SKCTAILTVEEPSI-NFTLRLPEF---ILVPANT-------DAY 1215 +D+ Y+CE N + +A L+VE P + + L +P + ++VP A Sbjct: 3031 EDSAVYTCEAKNDYGVATTSASLSVEIPEVVSPELEVPVYPPAVIVPLRDAVTSEGQSAR 3090 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA-K 1274 + L V+WY K I+ + F + L I + +D+ YT V ++ Sbjct: 3091 FQCRVTGTDLKVSWYSKDREIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNSVG 3150 Query: 1275 STTKLKVEVVEFPPKIV------DYEREYRI-----KRGSDVTLLVDY--------QAFP 1315 T + +E P KI+ + E E ++ +R + + V++ + P Sbjct: 3151 QVTSTAILKLEAPEKIMYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTP 3210 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 +W + I + ++L I + + D G Y + N G + Sbjct: 3211 NVKFQWYKAGREIYDGDKYSIRSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFL 3270 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPE---NTGNS---TIIYYVVEYQEIDTTEWIS 1429 T+ + P I ++DSS + D G S + +Y E EI +E S Sbjct: 3271 TVTEPPR-----FIKKLDSSRLVKQHDSTRYECKVGGSPEIKVTWYKGE-TEIHPSEKYS 3324 Query: 1430 VKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 + + + NL S + A N AS +T + K +KP Sbjct: 3325 MSFVDSVAVLEMHNLSVEDSGDYSCEAQNPA--GSASTSTSL-----KVKAPPAFTKKP- 3376 Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYEN-RXXXXXXXXXXXX 1544 + T D+ L C G P +++WY+D ++++++ K EN Sbjct: 3377 HPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSKKYKVMSENYLASIHILNVDTAD 3436 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C A ND G SC+ + + T + VG+ + A +EG P V Sbjct: 3437 VGEYHCKAVNDVG--SDSCIGSVTLRAPPTFVKKLSDVTVVVGETIELQAAVEGAQPISV 3494 Query: 1605 IWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 +W K+ G + + I+ E + ++I + +++ KY + N AG L V Sbjct: 3495 LWLKDKGEIIRESENLWISYSENVASLKIGNAEPTNAGKYICQIKNDAGFQECFAKLTVL 3554 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWIKVADVDRD 1722 + E P ++ + +S T+E DG ELT ++ + +E + K++ ++ Sbjct: 3555 EPAVIVEKPGPVKVTAGDSCTLECTV---DGTPELTARWFKDGNELSTDHKYKISFFNKV 3611 Query: 1723 VETYCIQK-LNENCEYMFRVIAQNPVGFSEALES 1755 + L ++ EY F V +N VG S S Sbjct: 3612 SGLKILNAGLEDSGEYTFEV--KNSVGKSSCTAS 3643 Score = 159 bits (386), Expect = 8e-37 Identities = 220/917 (23%), Positives = 364/917 (39%), Gaps = 105/917 (11%) Query: 414 PVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQY 473 PV+V GD+ ++ VA T E I Y DT + V+ H + + Sbjct: 3940 PVQVTVGDSA-SLQCQVAGTPEMI-----VSWYKGDTKLRGTATVKMHFKNQVATLVFSQ 3993 Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 + D ++ +Y+ K N + + T +E+ + P F KLR H G V F+C + Sbjct: 3994 V-DSDDSGEYICKVENT-VGEATSSSLLTVQERKLPPSFTRKLRDVHETVGLPVTFDCGI 4051 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G S+ ++ + DNV ED T N A Sbjct: 4052 AG-----------------SEPIEVSWFKDNVRV-------KEDYNVHTSFIDNVAILQI 4087 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY---VDEGSD 650 T+ + + T + EG P F P + E +D Sbjct: 4088 LKTDKSLMGQYT-----CTASNAIGTASSSGKLVLTEGKTPPFFDTPITPVDGIIGESAD 4142 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKFQEGTYT 709 EC + + W +EI N ++ +E+ H L I V + G YT Sbjct: 4143 F--ECHISGTQPIRVTWAKDNQEIRTGGNYQISYVENTAH-----LTILRVDRGDSGKYT 4195 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESVILSAQVVGNPRPTITW 768 A N G+ S L +K K PP L + +G + L +V G+ T++W Sbjct: 4196 CYASNEVGKDSCTAQLNVKE-RKTPPTFTRKLSEAVEETEGNELKLEGRVAGSQPLTVSW 4254 Query: 769 CKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPT 826 KNN+ V + P ++ +L K V D G+YT K N G ++ + + EP Sbjct: 4255 YKNNQEVHSSPHCEISFKNNTLLLHIKSVGQSDAGLYTCKVSNEAGSVLCTSSVVIREP- 4313 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 +PP+F Q +E T++L V + I W + I SE + +F Sbjct: 4314 ---KKPPVFDQPLQPAATEEGDTLQLSCHVRGSEPIRIQWLKAGREIRASERCSFSF-AN 4369 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------------DVE-KVTFVK 932 + L+ ++ DSG+Y C ASN AG + ++VT+ D+E K+ FV Sbjct: 4370 GVALLELAAVTKSDSGEYVCKASNVAGTDTCRSKVTVKEKAALVSAAKKADIEGKLYFVS 4429 Query: 933 HLQKSYETEEG-KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXX 990 Q E+ T I + + KW K R IIQ+ G Sbjct: 4430 EPQSIKVMEKTVATFIAKVGGDPIPNVKWMKGKWRQLNQGGRIIIQQRGDEAKLEIKDTT 4489 Query: 991 XXDVGVIKCIVKDQ----ETSTMLVV----KETIPEFIR-KLQDFEVKEKD-----VAIL 1036 D G+ KC+ +Q E S L V +E + E +R KL+ K+K+ + IL Sbjct: 4490 KTDSGLYKCVAFNQHGEIERSVNLQVEERKQEVVEEDVRGKLKRIPTKKKEDEEQTIDIL 4549 Query: 1037 EVEINSETADV--------VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 E+ N + + + + G + + K E+ H ++ + + ++ E+ Sbjct: 4550 ELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQTREEESHRLEIELTEKAQKEDQEFE 4609 Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF--EIELTKGDALVRWFKDGSEI 1146 ++ +T E P +I ++NQ V A F EI++ + + W+K ++ Sbjct: 4610 ELV--AFIQQRLTQTE-PVTLIRDIENQTVLTDEDAIFECEIKINYPEIKLSWYKGTQKL 4666 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI 1206 S+ ++ I+G + LKI +C L+D G Y G +A LTV EP++ L + Sbjct: 4667 DSSDKYKIKIEGDRHILKIKNCQLEDQGNYRIVCGPHIASARLTVIEPAVE--RHLHDTT 4724 Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCE 1265 NT L+ + WY+ I+ ++ T +SD K LII+ +DQ + Sbjct: 4725 FKEGNT-CTLSCQFSIPNAKSQWYRNGRPIKIGGRYSTQVSD-KVHKLIIKDVRTEDQGQ 4782 Query: 1266 YTCVLLDAKSTTKLKVE 1282 YTC L + ++T L +E Sbjct: 4783 YTCKLDNLETTADLTIE 4799 Score = 135 bits (327), Expect = 1e-29 Identities = 136/611 (22%), Positives = 249/611 (40%), Gaps = 34/611 (5%) Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V++ P + RL+ +V + A F E+ T + +W+K G EI + + Sbjct: 3179 VKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVKFQWYKAGREIYDGDKYSIRSSNYLS 3238 Query: 1162 KLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 L+I + D GEYSC+ N TA LTV EP F +L LV + Sbjct: 3239 TLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTVTEPP-RFIKKLDSSRLVKQHDSTRYE 3297 Query: 1218 VEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD---- 1272 ++ + VTWYK ++ I +EK+++ L + + +D +Y+C + Sbjct: 3298 CKVGGSPEIKVTWYKGETEIHPSEKYSMSFVDSVAVLEMHNLSVEDSGDYSCEAQNPAGS 3357 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 A ++T LKV+ PP + +GSDV L + Q P W + + I+ K Sbjct: 3358 ASTSTSLKVKA---PPAFTKKPHPVQTLKGSDVHLECELQGTPPFQISWYKDKREIRSSK 3414 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 K ++ AS+ I V+ D G Y + N+ G +VT+ P+ K + + + Sbjct: 3415 KYKVMSENYLASIHILNVDTADVGEYHCKAVNDVGSDSCIGSVTLRAPPTFVKKLSDVTV 3474 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITKTQTSIQNLKTNSSYR 1450 E ++++ + + I +E WIS I N + ++ + Sbjct: 3475 VVGETIELQAAVEGAQPISVLWLKDKGEIIRESENLWISYSE-NVASLKIGNAEPTNAGK 3533 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 + N+ E V++ I VEKP + + L C G P+ Sbjct: 3534 YICQIKNDAGFQ---ECFAKLTVLEPAVI----VEKP-GPVKVTAGDSCTLECTVDGTPE 3585 Query: 1511 PKVTWYRDGKKLKTA---KATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVG 1566 W++DG +L T K ++ N+ Y N G+ + + Sbjct: 3586 LTARWFKDGNELSTDHKYKISFFNKVSGLKILNAGLEDSGEYTFEVKNSVGKSSCTASLQ 3645 Query: 1567 IQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 + + + +K+ + ++G ++ + G PP V W+ +G ++ + +Y T + Sbjct: 3646 VSDRIMPPSFTRKLKETYGQLGSSAVLECKVYGSPPILVSWFHDGQEITSGDKYQATLTD 3705 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT- 1684 T +++ L+ S Y+ A+N AG+ L V + PS + P +S E++T Sbjct: 3706 NTCSLKVNGLQESDMGTYSCTATNVAGSDECSAFLSVREPPSFVKKPEPFNVLSGENITF 3765 Query: 1685 ---IEWKPPLD 1692 ++ PPL+ Sbjct: 3766 TSIVKGSPPLE 3776 Score = 129 bits (312), Expect = 7e-28 Identities = 107/433 (24%), Positives = 176/433 (40%), Gaps = 26/433 (6%) Query: 1643 YTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGLE 1697 + + A N G S +K+ D +P G + + + ++ SV + W+PPL+DGG Sbjct: 7500 FRVRAQNMVGVGKPSHPTRAVKITDPIERPSGNINLDHSDQTKTSVQLTWEPPLEDGGSP 7559 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757 + Y IE+ E ++WI+ + + L Y +RV A+N G S+ E+ Sbjct: 7560 ILGYIIERKEEGTDKWIRCNPKLVPACAFKVTGLKAGSSYYYRVSAENAAGVSDPAEA-- 7617 Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXX 1817 + D P D V + P PI Y + W Sbjct: 7618 -IGPLTADDPFVDLQWPLSAFKDGLEVIV---PEPIKIRVPITGYPIPTAT----WSFGD 7669 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSL-------PYTSDDKITIGKTLTPPSQPR 1870 R+ + +T + I + P +S L PS P+ Sbjct: 7670 QVLEEGGRVTMKTTSTFAELVITPSERPDKGIYTLTLENPVSSVSGEIDVNVLARPSAPK 7729 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 V + + +V L W PE +GGSP+ +YIIE + V K+W K++ E + ++ Sbjct: 7730 ELKVVDVSRSTVQLSWEPPEDDGGSPVIDYIIEKREVSRKTWIKVMD-HVIDQEFSVPDL 7788 Query: 1931 KEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 + E +FR+ A N G P + + + ATVP PP ++ R S + +W Sbjct: 7789 IQGKEYLFRVCACNKCGPGEPAYIDEPINMSAPATVPDPP-ENVKWRNPTSKGIFLTWEP 7847 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 P++DGGA + GY + W G+ + T K + L E Y R+ A N IG Sbjct: 7848 PKYDGGARIKGYLVEKCQRGTDKWEICGEPVIET-KMEVTKLKEGEWYAYRVKALNRIGA 7906 Query: 2050 SEPLESDEPFKVI 2062 S+P + + + I Sbjct: 7907 SKPSKPTDDIQAI 7919 Score = 118 bits (284), Expect = 2e-24 Identities = 114/469 (24%), Positives = 191/469 (40%), Gaps = 35/469 (7%) Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543 L+K+ K+ + P +E P V L+ K +G +V EC + G+P+P +TW Sbjct: 665 LRKESEAKVTETARVPVP-AEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTW 723 Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS--------- 594 +R+ I+ S DFQ+ + +A LVIRE F ED+G FTC A N AG S+ Sbjct: 724 YREDYKIESSMDFQITFKA-GLARLVIREAFAEDSGRFTCTATNKAGSVSTSCHLHVKVS 782 Query: 595 ----TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL-EGIPPTFSKKPKAQYVDEGS 649 T E I E +++ S + ++ E +PP F +KP + EG Sbjct: 783 EETETRETISEKVVTEEKSYVETKDVVMEDVSAAAEEVSGEPVPPFFIRKPVVHKLIEGG 842 Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 I+ EC++ P+P + W G + V+ + + C L+I+ G YT Sbjct: 843 SIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETG-ECK-LEISMTFADDAGEYT 900 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 +V N+ GEAS + L E + I+ + M+ + + + V P I++ Sbjct: 901 IVIRNKFGEASATVSL---LEEADYEAYIKSQQEMMYQTQVTAYVQEPKVAEVAPPISYG 957 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS--EGIAETSAVITVEEPTE 827 +K + T++ V+DE + E + I T++E E Sbjct: 958 DFDKEYEKEQALIRKKMAKDTVMVRTFVEDEEFHISSFEERLIKEIELRIIKTTLDELLE 1017 Query: 828 ENAEPPL------------FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 E+ E + F R + E + + T P+P I WY++ + I Sbjct: 1018 EDGEEMMIDISESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRH 1077 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 E + + V D G Y ASN G + A++ ++ Sbjct: 1078 GERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNMKGNAICSAKLYVE 1126 Score = 114 bits (275), Expect = 2e-23 Identities = 64/198 (32%), Positives = 99/198 (50%), Gaps = 4/198 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P RN V+E V L W EPES+GGS I Y++E + +K K+W +VT E+ Sbjct: 7327 PGPVRNLEVTEIYDGEVGLAWQEPESDGGSKIIGYVVERRDIKRKTWI-VVTDHAENCEY 7385 Query: 1926 CIENIKEKD-EIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIV 1983 + +++ E +FR+SA N VG P E++ V + VP PP +E+ V Sbjct: 7386 TVTGLQKGGVEYLFRVSARNRVGTGEPVETERPVEAKSKFEVPGPPQN-VEVTDVNRFGR 7444 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 +W PE+DGG+P+ GY I +R+ W + L + D+ EN Y R+ A Sbjct: 7445 TLTWEAPEYDGGSPITGYVIELRNRASIKWEPTMTTGADELSAVLTDVVENEEYFFRVRA 7504 Query: 2044 RNEIGLSEPLESDEPFKV 2061 +N +G+ +P K+ Sbjct: 7505 QNMVGVGKPSHPTRAVKI 7522 Score = 101 bits (243), Expect = 2e-19 Identities = 101/361 (27%), Positives = 168/361 (46%), Gaps = 35/361 (9%) Query: 1018 EFIRKLQDFEVKEKDV----AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 +F+++++D +KE + AI EV I+ TA W +DG I+ + K+ F G RK Sbjct: 5354 KFVKEMKDIVLKEAESVGSSAIFEVLISPSTAITSWMKDGSNIR-ESPKHKFIADGKDRK 5412 Query: 1074 LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEI 1128 L+I + + D GEY+C+LR +++ TA++ V ELP + L+ + V KG Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTC 5472 Query: 1129 ELTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK--C 1185 EL K ++V W +DG I+ L I G L I D D DAG Y+ V +S+ C Sbjct: 5473 ELNKERSVV-WRRDGKIIKDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDSELSC 5531 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI--EDTEKFT 1243 ++ + V E ++ ++ V A T +I +T ++ W+K I E T+K Sbjct: 5532 SSCVKVVEVIRDWLVKPIRDQHVKPKGTATFTCDIVKDTPNIKWFKGDEEIPAEPTDKTE 5591 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRG 1302 ++ + K L I+ D EY+ ++VE +P K+ ERE +K Sbjct: 5592 ILKEGNKIFLKIKNAGPADIGEYS-----------VEVEGRRYPAKLTLGEREVELLKPL 5640 Query: 1303 SDVTL----LVDYQAFPQPND---EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 DVT+ ++ D EW + +I++ + + LT+ KV+ A Sbjct: 5641 EDVTVYEKETANFDTEISEEDIPGEWKLKGEILRPSPTCEIKAEGGKRFLTLHKVKLEQA 5700 Query: 1356 G 1356 G Sbjct: 5701 G 5701 Score = 96.7 bits (230), Expect = 6e-18 Identities = 78/251 (31%), Positives = 110/251 (43%), Gaps = 10/251 (3%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 G+ A FE+ ++ A+ W KDGS I+ S + DGK +KL I D L DAGEY+C Sbjct: 5371 GSSAIFEVLISPSTAITSWMKDGSNIRESPKHKFIADGKDRKLHIIDVQLSDAGEYTCVL 5430 Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 +GN + TA L VEE + F L E + V YLT E+ E V W + +I Sbjct: 5431 RLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTCELNKER-SVVWRRDGKII 5489 Query: 1237 EDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE-FPPKIVDYE 1294 +D KF L +L I + D YT + D++ + V+VVE +V Sbjct: 5490 KDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDSELSCSSCVKVVEVIRDWLVKPI 5549 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVEN 1352 R+ +K T D PN +W + I K I + L IK Sbjct: 5550 RDQHVKPKGTATFTCDI-VKDTPNIKWFKGDEEIPAEPTDKTEILKEGNKIFLKIKNAGP 5608 Query: 1353 TDAGIYKLRLE 1363 D G Y + +E Sbjct: 5609 ADIGEYSVEVE 5619 Score = 94.7 bits (225), Expect = 2e-17 Identities = 49/133 (36%), Positives = 69/133 (51%), Gaps = 1/133 (0%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + + A I G P P++ W K L D I T S + I + KRS S Y Sbjct: 7940 KAGTKIELPAKITGKPEPQITWTKAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYI 7999 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 IEA N++G ++ V + V DKP P + EI+ ES + W PP DDGG ++T Y +E Sbjct: 8000 IEAVNSSGRATAVVEVNVLDKPG-PPAAFDVSEITNESCLLTWNPPRDDGGSKITNYVLE 8058 Query: 1705 KHEPDNNRWIKVA 1717 K D+ W K++ Sbjct: 8059 KRATDSEIWHKLS 8071 Score = 87.8 bits (208), Expect = 3e-15 Identities = 59/201 (29%), Positives = 99/201 (49%), Gaps = 13/201 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTH 787 +P V++P S+ QG++ +VVG P P W N + V + K DG T Sbjct: 1184 KPVFVLKPT-SVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDG-TQ 1241 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 S+ I+ P +D G + + A+N G A S ++VE +E+ P F+ R + ++VKE Sbjct: 1242 SLIIV-PAMPEDSGEWAVIAQNRAGKASVSVTLSVE--AKEDLVRPRFVERLRNVSVKEG 1298 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI--DSGDYK 905 + + + T NP P I W +N++II P + +G + N++S D+ Y Sbjct: 1299 SRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAAL-NIESTARQDAAWYT 1357 Query: 906 CVASNSAGKSSHGARVTIDVE 926 A N AG+ + +V ++VE Sbjct: 1358 ATAINKAGRDTTRCKVNVEVE 1378 Score = 83.8 bits (198), Expect = 5e-14 Identities = 60/225 (26%), Positives = 106/225 (47%), Gaps = 17/225 (7%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTK--SDGDTHSIT 790 P +PL+S++ +G + A + G P P ++W ++ + + A LP S D + Sbjct: 6 PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKL 65 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 ++ + G YT++A N G A ++A + V T PP F R Q +T ++ + Sbjct: 66 VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTA----PPNFSQRLQSMTARQGSQV 121 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 +L RVT P P + +YR+ I S +G+ L+I E DSG Y A+N Sbjct: 122 RLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPE-DSGTYSVNATN 180 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955 + G+++ A + I E +++ ++ KT++ Q S T Sbjct: 181 NVGRATSTAELLIQGE--------EEAVPAKKTKTIVSTAQISQT 217 Score = 81.4 bits (192), Expect = 2e-13 Identities = 55/204 (26%), Positives = 94/204 (46%), Gaps = 11/204 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F KP + +G + ++V P P+ W G+++V D + I+ D Sbjct: 1185 PVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKED---GTQ 1241 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752 L I G + V+A NR G+AS+ + L ++ E P+ +E L+++ V++G + Sbjct: 1242 SLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAKEDLVRPRFVERLRNVSVKEGSRL 1301 Query: 753 ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAE 808 ++ + GNP P I W KN+ P K + +G + + ++ +D YT A Sbjct: 1302 HMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGTKGAAALNIESTARQDAAWYTATAI 1361 Query: 809 NSEGIAETSAVITVEEPTEENAEP 832 N G T + VE E+AEP Sbjct: 1362 NKAGRDTTRCKVNVE---VEHAEP 1382 Score = 80.6 bits (190), Expect = 4e-13 Identities = 58/203 (28%), Positives = 98/203 (48%), Gaps = 11/203 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 PTF++ ++ EGS E + P P+++W G+ + V I SD Sbjct: 6 PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGR--- 62 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L I +V + G YT+ A N G+A+ L + G PP + L+SM RQG V Sbjct: 63 AKLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTA-PPNFSQRLQSMTARQGSQV 121 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L +V G P P + + ++ +++ P +GD +S+ I+ +D G Y++ A N Sbjct: 122 RLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSL-IIAEAYPEDSGTYSVNATN 180 Query: 810 SEGIAETSAVITVEEPTEENAEP 832 + G A ++A + ++ EE A P Sbjct: 181 NVGRATSTAELLIQ--GEEEAVP 201 Score = 78.2 bits (184), Expect = 2e-12 Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 31/245 (12%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E+ P+FV K G T +F+ +V G P P+ WF + ++ +D Sbjct: 1180 ERLYKPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDG 1239 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 +L+I PED+G + +A+N AG AS + L VEA Sbjct: 1240 TQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEA---------------------- 1277 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 D+ + P F ++ + V EGS + + + P PDI WL + IVP + + I Sbjct: 1278 KEDL---VRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRI 1334 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E + L I + + YT A+N+ G + + ++ EP EP + + Sbjct: 1335 EGTKG--AAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEP----EPERRL 1388 Query: 745 IVRQG 749 I+ +G Sbjct: 1389 IIPKG 1393 Score = 68.1 bits (159), Expect = 2e-09 Identities = 33/92 (35%), Positives = 56/92 (60%), Gaps = 1/92 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F ++L+ GS V+ + +V G P P + ++R I+ S DFQ+ + D + +L+ Sbjct: 104 PNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGD-LYSLI 162 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I E +PED+GT++ A N G A+ST EL+++ Sbjct: 163 IAEAYPEDSGTYSVNATNNVGRATSTAELLIQ 194 Score = 67.3 bits (157), Expect = 4e-09 Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 14/255 (5%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P PE V R + + + + W+PP DGG + Y +EK + ++W ++ + +ET Sbjct: 7825 PDPPEN-VKWRNPTSKGIFLTWEPPKYDGGARIKGYLVEKCQRGTDKW-EICG-EPVIET 7881 Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + KL E Y +RV A N +G S+ + ++ I A + P + ++ Sbjct: 7882 KMEVTKLKEGEWYAYRVKALNRIGASKPSKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKA 7941 Query: 1784 VYITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 P++ G P I + K E + + + I + + + I Sbjct: 7942 GTKIELPAKITGKPEPQITWTKAEKLLRPDDRITIETTPNHSTVTITDSKRSDSGTYIIE 8001 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N G + T+ ++ + L P P F VSE T+ S L W P +GGS ITNY Sbjct: 8002 AVNSSGRA---TAVVEVNV---LDKPGPPAAFDVSEITNESCLLTWNPPRDDGGSKITNY 8055 Query: 1901 IIEFKTVKGKSWTKI 1915 ++E + + W K+ Sbjct: 8056 VLEKRATDSEIWHKL 8070 Score = 64.5 bits (150), Expect = 3e-08 Identities = 36/108 (33%), Positives = 56/108 (51%), Gaps = 2/108 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 SE +++ F +L+ T +G+ V F C+ GYP P+I W++ I+ + + M Sbjct: 1028 SESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQ 1087 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APLSDHG 608 D A+L + V PED G +T A N G A + +L VE AP + G Sbjct: 1088 DGSASLRLPVVLPEDEGIYTVFASNMKGNAICSAKLYVEPVAPTATPG 1135 Score = 63.7 bits (148), Expect = 5e-08 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 4/111 (3%) Query: 495 LPVFEKPTSEEQSM---APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 +P F KP E S AP E+++ + G+ F +V G P P+ WFR I+ Sbjct: 1788 IPTF-KPEKVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIE 1846 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + Y+ +DNV LVIR+V +D+ + A N AG SS L+V+A Sbjct: 1847 RTDRIYWYWPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQA 1897 Score = 60.5 bits (140), Expect = 5e-07 Identities = 32/96 (33%), Positives = 52/96 (54%), Gaps = 3/96 (3%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS--QDFQMYYDDDNVA 566 AP F + L+ +GS FE + G+P P+++W+R ++ + Q+ + D A Sbjct: 5 APTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGR-A 63 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 LVI V ++G +T A N +G A+ST EL+V A Sbjct: 64 KLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTA 99 Score = 60.5 bits (140), Expect = 5e-07 Identities = 42/152 (27%), Positives = 71/152 (46%), Gaps = 6/152 (3%) Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 +K + V+++ + L+ E+ + ET+ V P E PP + + TV E ++ Sbjct: 653 IKGEAVREDHLL-LRKESEAKVTETARVPV---PAEIPVTPPTLVWGLKNKTVTEGESVT 708 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 L ++ +P P++TWYR + I S F LVI +E DSG + C A+N Sbjct: 709 LECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAE-DSGRFTCTATNK 767 Query: 912 AGKSSHGARVTIDVEKVTFVKH-LQKSYETEE 942 AG S + + V + T + + + TEE Sbjct: 768 AGSVSTSCHLHVKVSEETETRETISEKVVTEE 799 Score = 58.4 bits (135), Expect = 2e-06 Identities = 50/185 (27%), Positives = 79/185 (42%), Gaps = 9/185 (4%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNK-YDFEKRGHIRKL 1074 P F + LQ E A E I+ +V W RDG+++ KL Sbjct: 6 PTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKL 65 Query: 1075 YIRNTSVHDEGEYSCILRDES----CTAE--VTVVELPPEIITRLQNQKVNKGNKATFEI 1128 I + + + G Y+ + S TAE VT PP RLQ+ +G++ ++ Sbjct: 66 VIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRLDV 125 Query: 1129 ELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 +T +V++++DG EIQ S Q+ +G L I + +D+G YS N+ A Sbjct: 126 RVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVGRA 185 Query: 1188 ILTVE 1192 T E Sbjct: 186 TSTAE 190 Score = 56.8 bits (131), Expect = 6e-06 Identities = 52/177 (29%), Positives = 80/177 (45%), Gaps = 9/177 (5%) Query: 1196 INFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + F + + +L A + A V I T +W K S I ++ K I+D K R Sbjct: 5353 LKFVKEMKDIVLKEAESVGSSAIFEVLISPSTAITSWMKDGSNIRESPKHKFIADGKDRK 5412 Query: 1253 LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLV 1309 L I D EYTCVL + + T+ K+ V E P + V E E + +G + L Sbjct: 5413 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLTC 5472 Query: 1310 DYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 + + + W + KIIK K I S SLTI +++DAG Y + +E++ Sbjct: 5473 ELNK--ERSVVWRRDGKIIKDKPGKFALGIIGLSHSLTITDSDDSDAGTYTVTVEDS 5527 Score = 55.2 bits (127), Expect = 2e-05 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 2/98 (2%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +++ P V P +G T +F C+V GYP P++ W+ + +I+ S+ F++ Y D Sbjct: 1563 QKEKQKPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRKSKRFRLRY--D 1620 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + L I + D G A+N GF +L ++ Sbjct: 1621 GIHYLDIVDCKSYDTGEVKVTAENPEGFIEHKVKLEIQ 1658 Score = 54.0 bits (124), Expect = 4e-05 Identities = 39/191 (20%), Positives = 81/191 (42%), Gaps = 9/191 (4%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533 ++PT +PL+++ G P P+V+WYRDG+ L A + + R Sbjct: 4 KAPTFTQPLQSVVALEGSAATFEAHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRA 63 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592 Y A N G+ ++ + + ++ ++ + G + + Sbjct: 64 KLVIPSVTEANSGRYTIQATNGSGQATSTAELLVTAGTAPPNFSQRLQSMTARQGSQVRL 123 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + GIP P V +Y++G ++++ ++ I + + I E S Y++ A+N G Sbjct: 124 DVRVTGIPTPVVKFYRDGVEIQSSPDFQILQEGDLYSLIIAEAYPEDSGTYSVNATNNVG 183 Query: 1653 --TSSVEVTLK 1661 TS+ E+ ++ Sbjct: 184 RATSTAELLIQ 194 Score = 52.4 bits (120), Expect = 1e-04 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 6/127 (4%) Query: 1462 SDASET-TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 S+A T T V E + PT+ LKN T E + L C G PQP VTWYR+ Sbjct: 669 SEAKVTETARVPVPAEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTVTWYREDY 728 Query: 1521 KLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 K++++ + T++ + C A N G V TSC + ++ T + Sbjct: 729 KIESSMDFQITFKAGLARLVIREAFAEDSGRFTCTATNKAGSVSTSCHLHVKVSEE-TET 787 Query: 1577 NEDIKQK 1583 E I +K Sbjct: 788 RETISEK 794 Score = 49.2 bits (112), Expect = 0.001 Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%) Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + E E +A A+ V +E +P L + + V E T + RVT P+P + Sbjct: 1543 RIEELERMAHEGALPAVAVDQKEKQKPELVLVP-EPARVLEGETARFRCRVTGYPLPKVN 1601 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 WY N+++I S+ +DG + L I + S D+G+ K A N G H ++ I Sbjct: 1602 WYLNSQLIRKSKRFRLRYDGIHY-LDIVDCKS-YDTGEVKVTAENPEGFIEHKVKLEI 1657 Score = 48.4 bits (110), Expect = 0.002 Identities = 75/338 (22%), Positives = 131/338 (38%), Gaps = 30/338 (8%) Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI--AETSAVITVEEPTE 827 K KPVK K H + I KP+ + +T AE + ET + V E Sbjct: 602 KITKPVKPPQLKP----HEVKI-KPESAPPQFPFTEAAETYKAHYDVETKKEVDVSIKGE 656 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 E L + + E V E + + A + P P++ W N+ ++ E++T Sbjct: 657 AVREDHLLLRKESEAKVTETARVPVPAEIPVTP-PTLVWGLKNKTVTEGESVTLECHISG 715 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 E DYK +SS ++T V +++++ + G+ Sbjct: 716 HPQPTVTWYRE----DYKI-------ESSMDFQITFKAGLARLV--IREAFAEDSGRFTC 762 Query: 948 LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007 + +VST + + K + RE I E + DV +++D + Sbjct: 763 TATNKAGSVSTSCHLHVKVSEETETRETISE-KVVTEEKSYVETKDV-----VMEDVSAA 816 Query: 1008 TMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSETAD-VVWERDG-EIIKPKKNKYD 1064 V E +P F IRK ++ E I E ++ V+W++ G + + K Sbjct: 817 AEEVSGEPVPPFFIRKPVVHKLIEGGSIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVS 876 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 +++ KL I T D GEY+ ++R++ A TV Sbjct: 877 YKRETGECKLEISMTFADDAGEYTIVIRNKFGEASATV 914 Score = 48.0 bits (109), Expect = 0.003 Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TS 1628 KPV + +K G + G P PE W+ NG ++ ND + I KE T Sbjct: 1184 KPVFVLKPTSVKCSQ--GQTARFDLKVVGRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQ 1241 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + I S ++ + A N AG +SV VTL V K Sbjct: 1242 SLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEAK 1278 Score = 48.0 bits (109), Expect = 0.003 Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD- 561 ++E + P FVE+LR +GS + + G P P I W + + II P + ++ + Sbjct: 1277 AKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEG 1336 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 A L I +DA +T A N AG ++ ++ VE Sbjct: 1337 TKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVE 1376 Score = 48.0 bits (109), Expect = 0.003 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 2/123 (1%) Query: 481 TQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540 T L+ + EKI E+ E +API +L P +F C+VE P + Sbjct: 3155 TAILKLEAPEKI-MYEKLEEEIEMEVKVAPILRRRLEPLEVAVNHVAKFTCEVETTPNVK 3213 Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 W++ I + + + ++TL I D G ++C A N G SST L V Sbjct: 3214 FQWYKAGREIYDGDKYSI-RSSNYLSTLEIPRPQVVDCGEYSCKASNQHGSVSSTAFLTV 3272 Query: 601 EAP 603 P Sbjct: 3273 TEP 3275 Score = 47.6 bits (108), Expect = 0.004 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 +F + L + TV+ C++ P ++TWF+ + F+ Y D LVI Sbjct: 6701 VFTKNLHDLEVNENETVRLICEISK-PNAEVTWFKGDEEVPDGGRFE-YISDGRKRILVI 6758 Query: 571 REVFPEDAGTFTC 583 R PEDAG +TC Sbjct: 6759 RNAHPEDAGKYTC 6771 Score = 47.2 bits (107), Expect = 0.005 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ + I G P P V WY+ K+E+ ++ IT K + + I+E S ++T Sbjct: 704 GESVTLECHISGHPQPTVTWYREDYKIESSMDFQITFKAGLARLVIREAFAEDSGRFTCT 763 Query: 1647 ASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWK 1688 A+N AG+ S L V + ++ + + ++ E +E K Sbjct: 764 ATNKAGSVSTSCHLHVKVSEETETRETISEKVVTEEKSYVETK 806 Score = 46.0 bits (104), Expect = 0.011 Identities = 39/133 (29%), Positives = 65/133 (48%), Gaps = 10/133 (7%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM----AP-IFVE-KLRPKHTPD-GSTV 527 + E + Y K LN P KPT + Q++ AP IF++ KL T G+ + Sbjct: 7888 LKEGEWYAYRVKALNRIGASKP--SKPTDDIQAIDAKEAPEIFLDVKLLAGLTVKAGTKI 7945 Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + ++ G P PQITW + +++P D N +T+ I + D+GT+ A N Sbjct: 7946 ELPAKITGKPEPQITWTKAEKLLRP-DDRITIETTPNHSTVTITDSKRSDSGTYIIEAVN 8004 Query: 588 AAGFASSTTELIV 600 ++G A++ E+ V Sbjct: 8005 SSGRATAVVEVNV 8017 Score = 45.6 bits (103), Expect = 0.015 Identities = 39/158 (24%), Positives = 65/158 (41%), Gaps = 9/158 (5%) Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEV 1283 W+ + V+ D +I + ++LII +D E+ + + A + L VE Sbjct: 1218 WFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSVEA 1277 Query: 1284 VE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 E P+ V+ R +K GS + + V P P+ W+ NS II K+ + I+ Sbjct: 1278 KEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIEGT 1337 Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 +A+L I+ DA Y N G V + Sbjct: 1338 KGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNV 1375 Score = 45.2 bits (102), Expect = 0.020 Identities = 45/195 (23%), Positives = 81/195 (41%), Gaps = 8/195 (4%) Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775 E +LP V + EK+ P+++ + V +GE+ +V G P P + W N++ + Sbjct: 1553 EGALPAVA-VDQKEKQKPELVLVPEPARVLEGETARFRCRVTGYPLPKVNWYLNSQLIRK 1611 Query: 776 -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 K + DG H + I+ K D G + AEN EG E + +++ + + Sbjct: 1612 SKRFRLRYDG-IHYLDIVDCKSY-DTGEVKVTAENPEGFIEHKVKLEIQQREDFRSVLRR 1669 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 E V E G KL+ V + P+ + + +E IT E E + + Sbjct: 1670 APEPRHEPVVTEPG--KLLFEVQKIDKPAEATTKEVVKLKRAERITHEKLSEESEELRSK 1727 Query: 895 VDSEIDSGDYKCVAS 909 + G Y+ + + Sbjct: 1728 FKRRTEEGYYEAITA 1742 Score = 44.4 bits (100), Expect = 0.035 Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 15/165 (9%) Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 VK + EV+I E+A + E + K YD E + + + I+ +V ++ Sbjct: 607 VKPPQLKPHEVKIKPESAPPQFPFT-EAAETYKAHYDVETKKEV-DVSIKGEAVRED--- 661 Query: 1088 SCILRDESC-----TAEVTV-VELP---PEIITRLQNQKVNKGNKATFEIELT-KGDALV 1137 +LR ES TA V V E+P P ++ L+N+ V +G T E ++ V Sbjct: 662 HLLLRKESEAKVTETARVPVPAEIPVTPPTLVWGLKNKTVTEGESVTLECHISGHPQPTV 721 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 W+++ +I+ S Q+T +L I + +D+G ++C N Sbjct: 722 TWYREDYKIESSMDFQITFKAGLARLVIREAFAEDSGRFTCTATN 766 Score = 43.6 bits (98), Expect = 0.061 Identities = 53/278 (19%), Positives = 110/278 (39%), Gaps = 13/278 (4%) Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529 KV +++P + + +++ T D G P P+ W+R+G +++ Y Sbjct: 1795 KVELSPSMEAPKIFERIQSQTVAQGTDAHFRVRVVGKPDPECQWFRNGVQIERTDRIYWY 1854 Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISN-EDIKQKH 1584 +N A N GE + + +Q K +I+ I N +D+ K Sbjct: 1855 WPEDNVCELVIRDVTADDSASIMVKAVNIAGETSSHAFLLVQAKQLISFIQNLQDVVAKE 1914 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + D P +V W+KNG ++ + ++Y + + K + + ++ S + Y+ Sbjct: 1915 R--DSMATFECETSEPFIKVKWFKNGIEIHSGEKYRMHSDRKAHFLSVLAVEMSDADDYS 1972 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWKPPLDDGGLELTKYAI 1703 SV+ T K+ + + E + ++ ES T E + + +E Y Sbjct: 1973 CA---LVEDESVKTTAKLIVEGAVVEFIKELEDVEVPESFTGELECEVSPEDIEGKWYHG 2029 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 + N++++ + R + T ++ EY F V Sbjct: 2030 DVELSSNHKYVLASRRGRRILTIKDVNKDDQGEYSFVV 2067 Score = 41.5 bits (93), Expect = 0.25 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 6/122 (4%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A +S + + +E E P+F+ + + + T + +V P+P W Sbjct: 1159 ARSSPSCSPARRLDETDEGQLERLYKPVFVLKPTSVKCSQGQTARFDLKVVGRPMPETYW 1218 Query: 867 YRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + N + + T I DG L+I E DSG++ +A N AGK+S VT+ Sbjct: 1219 FHNGQQVVNDYTHKIVIKEDGTQ-SLIIVPAMPE-DSGEWAVIAQNRAGKAS--VSVTLS 1274 Query: 925 VE 926 VE Sbjct: 1275 VE 1276 Score = 41.5 bits (93), Expect = 0.25 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 13/132 (9%) Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + GI+ K + + +D+ +K + + V E IP V+W+KN +L K ++T Sbjct: 6161 IEGIRLKFITPL--KDVTKKERETAVFTVELSHENIP---VVWFKNDQRLHTSKVVSMTD 6215 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV-------TLKVYDKPSKPEGPVIMR 1676 K + IK+L +S+ +EA + + + V T K+ D + + VI++ Sbjct: 6216 DGKFHTLTIKDLTIDDTSQIRVEAMGKSSEAKLTVLEGDPYFTGKLQDYTAVEKDEVILQ 6275 Query: 1677 -EISRESVTIEW 1687 EIS+ ++W Sbjct: 6276 CEISKADAPVKW 6287 Score = 40.3 bits (90), Expect = 0.57 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 10/98 (10%) Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-----LPTKSDGDTH-SITILKP 794 LK+ +G V + G P P I W K+ K ++ + DG + ++ P Sbjct: 1041 LKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLP 1100 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 + DEG+YT+ A N +G A SA + V EP A P Sbjct: 1101 E---DEGIYTVFASNMKGNAICSAKLYV-EPVAPTATP 1134 Score = 39.5 bits (88), Expect = 0.99 Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P P++ WYK+G ++ + + Y++ ++ ++ +R+ + YT+ ASN G + Sbjct: 1060 GYPLPKIAWYKDGKRIRHGERYHMEVLQDGSASLRLPVVLPEDEGIYTVFASNMKGNAI- 1118 Query: 1657 EVTLKVYDKPSKP 1669 + K+Y +P P Sbjct: 1119 -CSAKLYVEPVAP 1130 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 4/77 (5%) Query: 1594 AVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 A I G P PEV WY++G L I+ + + + I + ++S +YTI+A+N + Sbjct: 27 AHISGFPVPEVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGS 86 Query: 1652 G--TSSVEVTLKVYDKP 1666 G TS+ E+ + P Sbjct: 87 GQATSTAELLVTAGTAP 103 Score = 38.3 bits (85), Expect = 2.3 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 13/169 (7%) Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 L K +T + + K V +E Y E + + E + EE + E PP FI Sbjct: 777 LHVKVSEETETRETISEKVVTEEKSYV---ETKDVVMEDVSA-AAEEVSGEPV-PPFFIR 831 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN----IELVIT 893 + + E G+I +V NP P + W + ++ ++ E +E+ +T Sbjct: 832 KPVVHKLIEGGSIIFECQVGGNPKPHVLWKKGGVPLTTGYRYKVSYKRETGECKLEISMT 891 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK-SYETE 941 D D+G+Y V N G++S + + + ++K Q+ Y+T+ Sbjct: 892 FAD---DAGEYTIVIRNKFGEASATVSLLEEADYEAYIKSQQEMMYQTQ 937 Score = 37.9 bits (84), Expect = 3.0 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 17/173 (9%) Query: 958 TKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012 T W+HN +++ + H+ +I+E D G I +++ S L V Sbjct: 1216 TYWFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASVSVTLSV 1275 Query: 1013 --KETI--PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK-NKYDFE 1066 KE + P F+ +L++ VKE + V+ D+VW ++ +II P K + E Sbjct: 1276 EAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKYPRIRIE 1335 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCIL-----RDES-CTAEVTVVELPPEIITRL 1113 L I +T+ D Y+ RD + C V V PE RL Sbjct: 1336 GTKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEPEPERRL 1388 Score = 37.5 bits (83), Expect = 4.0 Identities = 16/50 (32%), Positives = 25/50 (50%) Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 I E++ + LKN T + C G P PK+ WY+DGK+++ Sbjct: 1027 ISESEAIGAGFDLRLKNYRTFEGTGVTFHCKTTGYPLPKIAWYKDGKRIR 1076 Score = 37.1 bits (82), Expect = 5.3 Identities = 43/180 (23%), Positives = 71/180 (39%), Gaps = 7/180 (3%) Query: 1226 DVTWYKKKSVIED-TEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLD----AKSTTKL 1279 +V+WY+ V+ T IS R L+I TE + YT + A ST +L Sbjct: 36 EVSWYRDGQVLSAATLPGVQISFSDGRAKLVIPSVTEANSGRYTIQATNGSGQATSTAEL 95 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 V PP + ++GS V L V P P ++ + I+ + + Sbjct: 96 LVTAGTAPPNFSQRLQSMTARQGSQVRLDVRVTGIPTPVVKFYRDGVEIQSSPDFQILQE 155 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDSSSIN 1398 SL I + D+G Y + NN G A + I ++ + P K + ++ I+ Sbjct: 156 GDLYSLIIAEAYPEDSGTYSVNATNNVGRATSTAELLIQGEEEAVPAKKTKTIVSTAQIS 215 Score = 36.7 bits (81), Expect = 7.0 Identities = 35/174 (20%), Positives = 67/174 (38%), Gaps = 10/174 (5%) Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXX--XXXXYKCIAFNDHGEVET 1561 G P P+ W+ +G+++ T K + + IA N G+ Sbjct: 1210 GRPMPETYWFHNGQQVVNDYTHKIVIKEDGTQSLIIVPAMPEDSGEWAVIAQNRAGKASV 1269 Query: 1562 SCVVGIQQKPVITISN--EDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617 S + ++ K + E ++ K G + G P P+++W KN + + K Sbjct: 1270 SVTLSVEAKEDLVRPRFVERLRNVSVKEGSRLHMAVKATGNPNPDIVWLKNSDIIVPHKY 1329 Query: 1618 -EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 I + + + I+ R ++ YT A N AG + + V + ++PE Sbjct: 1330 PRIRIEGTKGAAALNIESTARQDAAWYTATAINKAGRDTTRCKVNVEVEHAEPE 1383 >UniRef50_Q7JN85 Cluster: Twitchin; n=6; Bilateria|Rep: Twitchin - Caenorhabditis elegans Length = 6048 Score = 318 bits (782), Expect = 8e-85 Identities = 294/1168 (25%), Positives = 488/1168 (41%), Gaps = 66/1168 (5%) Query: 935 QKSYETEEGKTVILECQTSH-TVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXX 992 +K+ + + K +C S +WY ++KEI SG +I+ E Sbjct: 25 EKTVQQQVDKICEWKCTYSRPNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVD 84 Query: 993 DVGVIKCIVKDQETSTMLVVKETIPE--FIRKLQDF-EVKEKDVAILEVEINSETADVVW 1049 D G C T L V E + F+ L + E+ A+L ++N+ A +VW Sbjct: 85 DTGKYTCEANGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVW 144 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSC-ILRDESCTAEVTVVELPP 1107 R + I+ ++ EK R L I+ D+ E++ I +D +V V E Sbjct: 145 YRGSKAIQEGDPRFIIEKDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRH 204 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166 + +++QKVN+ + AT E ++ DA V W+ DG I ++ +K++L I Sbjct: 205 TFVVPMKSQKVNESDLATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIIN 264 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 ++D GEY C + + A L V+ + F + L + ++ + D L + D Sbjct: 265 GARIEDHGEYKCTTKDDRTMAQLIVDAKN-KFIVALKDTEVIEKD-DVTLMCQTKDTKTP 322 Query: 1227 VTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 W++ I KF S TL I K ++ Y + + + V Sbjct: 323 GIWFRNGKQISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLEA 382 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP----QPNDEWIVNSKIIKK--CKHTKPSI 1338 E P + ++ K G + V +Q P + + N K I + K + I Sbjct: 383 EKRPILNWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVII 442 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397 A + K + D G + L L N+ G A + + DKP PP P + + + Sbjct: 443 KDDVAEIVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGL 502 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 ++ W P+ + + Y++E QE + W V T +++LK + Y+FR A+N Sbjct: 503 DLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGTDFKVKDLKEHGEYKFRVKALN 562 Query: 1458 EVDISD--ASETT----EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--- 1508 E +SD E+ Y K + + V+K + EP E+ I G + Sbjct: 563 ECGLSDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHCTLAWEPPEEDGGAPITGYIIER 622 Query: 1509 -PQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 + + W++ G+ T K E++ C DHG+ Sbjct: 623 REKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPC----DHGKP--- 675 Query: 1563 CVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + +K + IK + KVG+ I G P PE +W NG L+ + Sbjct: 676 -IKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKM 734 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 +++ +++I+ R+ S K+TI N++G+ T+ V +P+ P+GP+ + ++ + Sbjct: 735 SSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPTPPKGPLDIADVCAD 794 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 T+ W PP DDGG LT Y +E + DN ++I+V VD + T + L Y FR Sbjct: 795 GATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFR 854 Query: 1741 VIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A N G SE L ++ IK D P D + + I W P K+GG+PI Sbjct: 855 VKAVNNEGESEPLSADQYTQIKDPWDEPG-KPGRPEITDFDADRIDIAWEPPHKDGGAPI 913 Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 +Y VE++ + K+WK A I L YQFR+ A N+ G P +K Sbjct: 914 EEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQL 973 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK---I 1915 P + + S + T++W GG PI E K KG + Sbjct: 974 AKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGEPIP----EVKWFKGNQQLENGIQ 1027 Query: 1916 VTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 +T+ +EH CI + D +R++ +N+ G + +V L++ PS P P Sbjct: 1028 LTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV-LDR----PSKPNGP 1082 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 LE+ V + + SW P+ DGG P+ Y + D W+ K V K +I L Sbjct: 1083 LEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAK--VKDTKAHIDGLK 1140 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + TY R+ A N+ G S+ L +D+ K Sbjct: 1141 KGQTYQFRVKAVNKEGASDALSTDKDTK 1168 Score = 253 bits (619), Expect = 5e-65 Identities = 203/787 (25%), Positives = 318/787 (40%), Gaps = 29/787 (3%) Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P ++D +E ++K G D +L + P P W ++ K + + Sbjct: 2158 PPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKF 2217 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404 +K+ +D G Y ++ EN G E+ VT+LD PS P P ++ I ++ W EP Sbjct: 2218 HVKRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEP 2277 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 E+ G + I +YV+E Q+ T W + T + +L Y+FR AVN SD Sbjct: 2278 EDDGGAEISHYVIEKQDAATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPK--VTWYRDGK 1520 E E + K+ ++ P + + D++ T GG P V Sbjct: 2338 LEAREAI-IAKDPFDRADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISN 1577 A ++ A N GE + S + + + + N Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456 Query: 1578 ED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVIRIKE 1634 D + Q+ K G +EG P P++ W+ NG+ L + +I + + + K Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 R+ S KY I A+N +G EV + + D P PEGP+ ++I++ESV ++W PLDDG Sbjct: 2517 TARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDG 2576 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 G +T Y +EK E D RW+ + + + KL+E EY FRV A N G S L Sbjct: 2577 GSPITNYVVEKQE-DGGRWVPCGETSDT--SLKVNKLSEGHEYKFRVKAVNRQGTSAPLT 2633 Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW 1813 S+ IV K D P D + V + W P +GG+PI Y VE K + W Sbjct: 2634 SDHAIVAKNPFDEPDAPTDVTPVDW-DKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW 2692 Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 A L+ TYQFR+ A N+ G P + P Sbjct: 2693 VECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLA 2752 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 ++ +K +P+ + T+ + + S H ++ Sbjct: 2753 GLLDLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVR 2812 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 D +++I EN G + +V VP P PL+I + +W P Sbjct: 2813 -GDTGVYKIIVENEHGKDTAQCNVTV-----LDVPGTPEGPLKIDEIHKEGCTLNWKPPT 2866 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 +GG +L Y + D ++ W EVG T K N L Y R+ A N G S+ Sbjct: 2867 DNGGTDVLHYIVEKMDTSRGTWQEVGTFPDCTAKVN--KLVPGKEYAFRVKAVNLQGESK 2924 Query: 2052 PLESDEP 2058 PLE++EP Sbjct: 2925 PLEAEEP 2931 Score = 251 bits (614), Expect = 2e-64 Identities = 192/700 (27%), Positives = 290/700 (41%), Gaps = 32/700 (4%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 PKI+ R+ +IK G L VD+ P P W V S + S+ Sbjct: 3040 PKILTASRKIKIKAGFTHNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFF 3099 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406 + D+G YKL+++N G + V + D+PS P P + ++ S + W P++ Sbjct: 3100 PSAKRADSGNYKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKD 3159 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G + I YVVE ++ T W+ V +T T ++ L Y FR A N SD+ Sbjct: 3160 DGGAEISNYVVEKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSL 3219 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVPQPKVTWYR-DG 1519 T E V+ + +P KP + I N+ I++ GG P R D Sbjct: 3220 NTDE--PVLAKDPFGTPG--KPGRPEIVDTDNDHIDIKWDPPRDNGGSPVDHYDIERKDA 3275 Query: 1520 KKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKP 1571 K + K Y+ +A N G + S + + P Sbjct: 3276 KTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAP 3335 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 + + + + K G+ ++T P P++ W K G K E TT +T ++ Sbjct: 3336 KFDLDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLAGVE---TTDSQTKLV- 3391 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 I +RS S I+A N G + + + V DKP PE + +SR + T+ W P Sbjct: 3392 IPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGAPEN-ITYPAVSRHTCTLNWDAPK 3450 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DDGG E+ Y IE E + W KV + Y ++ L +Y FR+ A+N VG S+ Sbjct: 3451 DDGGAEIAGYKIEYQEVGSQIWDKVPGLISGT-AYTVRGLEHGQQYRFRIRAENAVGLSD 3509 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQE 1809 + P+VIK D P D V + W P +GGSPI+ Y VE K+ Sbjct: 3510 YCQGVPVVIKDPFDPPGAPSTPEITGY-DTNQVSLAWNPPRDDGGSPILGYVVERFEKRG 3568 Query: 1810 GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 G W + L N TYQFR+ A N G P + +T + P Sbjct: 3569 GGDWAPVKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPG 3628 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P V + T S L W P +GG+PI YI+E K + WT+ + Sbjct: 3629 APDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEV 3688 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 +N+ EK+E FR+ A N+ G P++ S V +E+ P Sbjct: 3689 KNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRP 3728 Score = 250 bits (612), Expect = 3e-64 Identities = 205/772 (26%), Positives = 332/772 (43%), Gaps = 29/772 (3%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 IK G+DV V + P P EWI N K + K S D K+ ++ AG+Y Sbjct: 1289 IKVGNDVEFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTR-FVLRGATRKHAGLY 1347 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 L N G + V +L KPS P G + + ++ W PE+ G + I +Y + Sbjct: 1348 TLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEI 1407 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 E ++ T W+ T+T++ NL+ Y+FR AVN+ SD T ++ + Sbjct: 1408 EKMDLATGRWVPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNT--AILAKN 1465 Query: 1478 KIQSP-TVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGK--KLKTAKATYENRX 1533 + P V+KP + + D+ GG P + K + + A ++ Sbjct: 1466 PYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQK 1525 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVITISNEDIKQKH-KVGD 1588 ++ A N G + S VV + I ED+ KVG Sbjct: 1526 TATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGA 1585 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 I+G P P+V W NG + K I + S + + R S KYTI A+ Sbjct: 1586 TLKFIVHIDGEPAPDVTWSFNGKGIGESKA-QIENEPYISRFALPKALRKQSGKYTITAT 1644 Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 N GT SV + +KV KP+KP+GP+ + ++ + T++WKPP DDGG + Y IEK Sbjct: 1645 NINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNT 1704 Query: 1709 DNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDV 1766 + W+ R +T + + LN+ Y FRV A N G S+ LE+E I+ K D Sbjct: 1705 KDGIWVPCG---RSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDR 1761 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXA 1824 P D++ V + W P +GG+PI +Y++E + + +W+ A Sbjct: 1762 PDRPGRPEPTDW-DSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPGGQTTA 1820 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 + L+ N Y+FR+ A N+ G S P + + P R+ + + + ++ Sbjct: 1821 TVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSI 1880 Query: 1885 KWTEPESNGGSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 + P S +P +T + + + ++ K+ + ++ ++ D F I A Sbjct: 1881 SFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQ-SKLVVKQMERGDSGTFTIKAV 1939 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 N G T +V ++K P+ P PL++ V + V +W P+ DGG P+ Y I Sbjct: 1940 NANGEDEATVKINV-IDK----PTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVI 1994 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 D W+ KV + + L H Y R+ A N G S+PLE+ Sbjct: 1995 EKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLET 2046 Score = 243 bits (595), Expect = 4e-62 Identities = 201/779 (25%), Positives = 317/779 (40%), Gaps = 36/779 (4%) Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAG 1356 R+K G + V+ + P P EW +N + +T ++ + LT K D+G Sbjct: 2464 RVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSG 2523 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415 YK+ N G + E++V ILD P P P +I S+ + WDEP + G S I Y Sbjct: 2524 KYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNY 2583 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 VVE QE D W+ + T + L Y+FR AVN S + T + ++ Sbjct: 2584 VVEKQE-DGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTS--APLTSDHAIVA 2640 Query: 1476 ETKIQSPTVEKPLKNITTEPNE-DIELT--CIFGGVP-QPKVTWYRD--GKKLKTAKATY 1529 + P + + + + D+E GG P + +D G ++ A+ Sbjct: 2641 KNPFDEPDAPTDVTPVDWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDWVECARVDG 2700 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ----KH 1584 + ++ A N G + S G + KP ++ + Sbjct: 2701 KT-TKATADNLTPGETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRI 2759 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + EG P P W N ++ ++T +S I I R + Y Sbjct: 2760 KAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYK 2819 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I N G + + + V D P PEGP+ + EI +E T+ WKPP D+GG ++ Y +E Sbjct: 2820 IIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVE 2879 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763 K + W +V D T + KL EY FRV A N G S+ LE+ EPI+ K Sbjct: 2880 KMDTSRGTWQEVGTFP-DC-TAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQ 2937 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822 DVP D + + I W P+ NGG+P+ Y VE K++G W Sbjct: 2938 FDVPDPVDKPEVTDW-DKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGT 2996 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSESTS 1879 L Y+FR+ A N G S P +D +IT + L P + R + + Sbjct: 2997 TFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFT 3056 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 ++ + + P + + + + +V S + K D ++ Sbjct: 3057 HNLEVDFI----GAPDPTATWTVG-DSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYK 3111 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 + +N +G E +++ PS P PLE+ V + + +W P+ DGGA + Sbjct: 3112 LKVKNELG-----EDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEIS 3166 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 Y + RD W+ V T + L+E H Y R+ A N G S+ L +DEP Sbjct: 3167 NYVVEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEP 3224 Score = 242 bits (593), Expect = 6e-62 Identities = 195/777 (25%), Positives = 315/777 (40%), Gaps = 33/777 (4%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K G+ + +V P P+ W N K I + K + + + + K +G Y Sbjct: 1581 VKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESK-AQIENEPYISRFALPKALRKQSGKY 1639 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + N G V +N+ + KP+ P P + ++ + W PE+ G I +Y + Sbjct: 1640 TITATNINGTDSVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEI 1699 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 E W+ T ++ +L Y+FR AVN SD ET ++ + Sbjct: 1700 EKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETET--DILAKN 1757 Query: 1478 KIQSPTVEKPLKNITTEPNED-IELT----CIFGGVPQPKVTWYRDGK--KLKTAKATYE 1530 P ++P + T+ + D ++L GG P + + K + + A Sbjct: 1758 PFDRP--DRPGRPEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIEKRTKYGRWEPAITVPG 1815 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKH-K 1585 + ++ +A N G + S V+ + I + +K K Sbjct: 1816 GQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIK 1875 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G + G P P V W+ N+ + N + E S + +K+++R S +T Sbjct: 1876 AGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFT 1935 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I+A N G V + V DKP+ P GP+ + ++ + VT+ W+ P DDGG+ + Y IE Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIE 1995 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763 K++ + RW+ A V D T + L EY FRV A N G S+ LE+ + K Sbjct: 1996 KYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDP 2055 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXX--XX 1820 D P D + V + W P +GG+PI +Y VE+K E W Sbjct: 2056 FDKPGKTNAPEITDW-DKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAG 2114 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 A + L + Y+FRI A+N+ G P S + + + PP RN + Sbjct: 2115 QTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNV-PPVIDRNSIQEIKVKA 2173 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 P S +P + E V+ K+ G H ++ D + I Sbjct: 2174 GQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFH-VKRALRSDTGTYII 2232 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 AEN G T V + H PS P PL++ + + +W PE DGGA + Sbjct: 2233 KAENENGTD--TAEVKVTVLDH---PSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISH 2287 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 Y I +D W G + F++ DL++ H Y R+ A N G S+PLE+ E Sbjct: 2288 YVIEKQDAATGRWTACG--ESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEARE 2342 Score = 235 bits (575), Expect = 1e-59 Identities = 208/783 (26%), Positives = 318/783 (40%), Gaps = 56/783 (7%) Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + RIK G+ + L + ++ P P +W N I + S+++ I D Sbjct: 2756 DLRIKAGTPIKLDIAFEGEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDT 2815 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIY 1414 G+YK+ +EN G + NVT+LD P P P I EI + W P + G + +++ Sbjct: 2816 GVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLH 2875 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 Y+VE + W V + L Y FR AVN S E E Sbjct: 2876 YIVEKMDTSRGTWQEVGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAK 2935 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 + + P V+KP + DI+ T GG P VT Y KK K + E Sbjct: 2936 NQFDVPDP-VDKPEVTDWDKDRIDIKWNPTANNGGAP---VTGYIVEKKEKGSAIWTEAG 2991 Query: 1533 XXXXXXXXXXXXX----XXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQ 1582 ++ IA N G + S Q KP I ++ IK Sbjct: 2992 KTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKI 3051 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K V + G P P W + E + K T+ I KR+ S Sbjct: 3052 KAGFTHNLEVDFI--GAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGN 3109 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y ++ N G + V D+PS PEGP+ + +++++S + WKPP DDGG E++ Y Sbjct: 3110 YKLKVKNELGEDEAIFEVIVQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYV 3169 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761 +EK + N W+ V+ + + KL E EY FRV+A+N G S++L + EP++ K Sbjct: 3170 VEKRDTKTNTWVPVSAFVTGT-SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAK 3228 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXX 1819 P DN+ + I W P NGGSP+ Y +E K + G+ K Sbjct: 3229 DPFGTPGKPGRPEIVDT-DNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSP 3287 Query: 1820 XXXXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-----QPR 1870 A R+QK TY++R+ A N+ G P S T P + Sbjct: 3288 VQGTAFSDTRVQK---GHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGK 3344 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 F V +T+ +T SP + I + GK + T S + I + Sbjct: 3345 EFRVKAGEPLVITIPFT------ASPQPD--ISWTKEGGKPLAGVETT-DSQTKLVIPST 3395 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWG 1988 + D +I A N G + ++++ TV P AP I V + +W Sbjct: 3396 RRSDSGPVKIKAVNPYGEA----EANIKI----TVIDKPGAPENITYPAVSRHTCTLNWD 3447 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P+ DGGA + GY I ++V +W +V + ++ + +R L Y RI A N +G Sbjct: 3448 APKDDGGAEIAGYKIEYQEVGSQIWDKVPGL-ISGTAYTVRGLEHGQQYRFRIRAENAVG 3506 Query: 2049 LSE 2051 LS+ Sbjct: 3507 LSD 3509 Score = 234 bits (572), Expect = 2e-59 Identities = 202/786 (25%), Positives = 335/786 (42%), Gaps = 42/786 (5%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKV 1350 D + +K G+ V V P P +W N ++ + T + ++ L I Sbjct: 986 DNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSA 1045 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409 +D G Y+L ++N+ G + + N+T+LD+PS P P + ++ ++N+ W P++ G Sbjct: 1046 MRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGG 1105 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I YY VE + T W+ + T+ I LK +Y+FR AVN+ SDA T Sbjct: 1106 EPIEYYEVEKLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTD- 1164 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVPQPK----VTWYRDGKKLKT 1524 K+TK ++P ++P K T + + D + + P+ +T Y KK K Sbjct: 1165 -----KDTKAKNP-YDEPGKTGTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKH 1218 Query: 1525 AKATYE------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVGIQQKPVIT 1574 + E ++ ++ A N G E S VV + Sbjct: 1219 GRDWQECGKVSGDQTNAEILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPW 1278 Query: 1575 ISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 I E +K KVG++ + G PPP+ W N K +D++ I +++ + ++ Sbjct: 1279 IDREAMKTITIKVGNDVEFDVPVRGEPPPKKEWIFN-EKPVDDQKIRIESEDYKTRFVLR 1337 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 R H+ YT+ A+N +G+ V + V KPS P GP+ + + + +EWK P DD Sbjct: 1338 GATRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDD 1397 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753 GG + Y IEK + RW+ + T + L EY FRV A N G S+ L Sbjct: 1398 GGAPIDHYEIEKMDLATGRWVPCGRSETTKTT--VPNLQPGHEYKFRVRAVNKEGESDPL 1455 Query: 1754 ESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812 + I+ K +VP D + V + W + +GG+PI + +E K + + Sbjct: 1456 TTNTAILAKNPYEVPGKVDKPELVDW-DKDHVDLAW-NAPDDGGAPIEAFVIEKKDKNGR 1513 Query: 1813 WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 W+ A + L YQFRI ARN+ GT P D++ P R Sbjct: 1514 WEEALVVPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHR 1573 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 + + TLK+ +P + K + G+S +I + + Sbjct: 1574 EDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGI-GESKAQIEN-EPYISRFALPKA 1631 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 K + I+A N G T+S ++ + K + P+ P P+E+ V + W P Sbjct: 1632 LRKQSGKYTITATNING----TDSVTINI-KVKSKPTKPKGPIEVTDVFEDRATLDWKPP 1686 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 E DGG P+ Y I + +W+ G+ F + L++ Y R+ A N G S Sbjct: 1687 EDDGGEPIEFYEIEKMNTKDGIWVPCGR--SGDTHFTVDSLNKGDHYKFRVKAVNSEGPS 1744 Query: 2051 EPLESD 2056 +PLE++ Sbjct: 1745 DPLETE 1750 Score = 223 bits (545), Expect = 4e-56 Identities = 187/787 (23%), Positives = 310/787 (39%), Gaps = 40/787 (5%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 D + IK G ++ V P P W +++ I+ K + L +K++ Sbjct: 1867 DALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQM 1926 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409 E D+G + ++ N G + + + ++DKP+ P P ++ ++ + + W P++ G Sbjct: 1927 ERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGG 1986 Query: 1410 STIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 I YV+E + + W+ + KT + L Y+FR V V+ S+ Sbjct: 1987 IPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFR---VAAVNAEGESDP 2043 Query: 1468 TEYYKVIKETKIQSPTVEKPLKN----ITTEPNEDIELT----CIFGGVP-QPKVTWYRD 1518 E + T + +KP K IT + ++L GG P + V +D Sbjct: 2044 LETFG----TTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKD 2099 Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV 1572 + ++ A N G S V + P Sbjct: 2100 EFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPP 2159 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 + N + K K G ++ + + G P P + W G +E+D + ++ + + Sbjct: 2160 VIDRNSIQEIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHV 2219 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 K RS + Y I+A N GT + EV + V D PS P GP+ + I ++ + WK P D Sbjct: 2220 KRALRSDTGTYIIKAENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPED 2279 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 DGG E++ Y IEK + RW + +D + + L + EY FRV A N G S+ Sbjct: 2280 DGGAEISHYVIEKQDAATGRWTACGE-SKDT-NFHVDDLTQGHEYKFRVKAVNRHGDSDP 2337 Query: 1753 LES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811 LE+ E I+ K D + D + + W P +GG+PI Y VE++ Sbjct: 2338 LEAREAIIAKDPFD-RADKPGTPEIVDWDKDHADLKWTPPADDGGAPIEGYLVEMRTPSG 2396 Query: 1812 KW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W A + L TYQFR+ A N+ G S P + P Sbjct: 2397 DWVPAVTVGAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKIN 2456 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929 R+ V++ TL + +P + + + T I + + ++ Sbjct: 2457 RDMFVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKS 2516 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 D ++I A N G + V + +P P PL + + V+ W Sbjct: 2517 TARADSGKYKIVATNESG----KDEHEVDV-NILDIPGAPEGPLRHKDITKESVVLKWDE 2571 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 P DGG+P+ Y + + W+ G+ +LK N LSE H Y R+ A N G Sbjct: 2572 PLDDGGSPITNY-VVEKQEDGGRWVPCGETSDTSLKVN--KLSEGHEYKFRVKAVNRQGT 2628 Query: 2050 SEPLESD 2056 S PL SD Sbjct: 2629 SAPLTSD 2635 Score = 209 bits (510), Expect = 7e-52 Identities = 163/679 (24%), Positives = 292/679 (43%), Gaps = 28/679 (4%) Query: 1295 REYRIKRGSDVTLLVDYQAF-PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 ++ ++ G + + + Y P+P + + I + + T ++ +T + + Sbjct: 3736 KDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRS 3795 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412 DAG YK+ N G ++NV +LD P P P +I + ++ + W P++ G I Sbjct: 3796 DAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAI 3855 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 YVVE + +W++V + T ++NL N+ Y FR A N+ + + ET + Sbjct: 3856 TNYVVE-KRTPGGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDD--A 3912 Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELT--CIFGGVP-QPKVTWYRDGKKLKTAKAT 1528 ++ + +P +P T+E ++ T GG P Q V R+ + KA Sbjct: 3913 IVAKNPFDTPGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAA 3972 Query: 1529 YENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQK 1583 + N Y + A+N G+ E S + P N + + Sbjct: 3973 FGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTR 4032 Query: 1584 HKV---GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSH 1639 + G+ + P P+V + K NK+ D + + + + I++ + + Sbjct: 4033 DILAYAGERAKILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTD 4092 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 Y +E N+ G+ S + LKV DKP+ P+ + + +I+ + T+ W PP DGG +T Sbjct: 4093 GGLYFVELENSQGSDSASIRLKVVDKPASPQ-HIRVEDIAPDCCTLYWMPPSSDGGSPIT 4151 Query: 1700 KYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756 Y +EK + + +W KV+ R++ Y + L ++ Y FRV A+ G SE E ++ Sbjct: 4152 NYIVEKLDLRHSDGKWEKVSSFVRNL-NYTVGGLIKDNRYRFRVRAETQYGVSEPCELAD 4210 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW-- 1813 +V K +VP+ D+ + W P ++GGS II Y+V+ + +W Sbjct: 4211 VVVAKYQFEVPNQPEAPTVRDK-DSTWAELEWDP-PRDGGSKIIGYQVQYRDTSSGRWIN 4268 Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 AR+ L N ++FRI A+N G S P ++ + PP P + Sbjct: 4269 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVG 4328 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 T+ W P +GGS IT Y +E + WT E ++ ++E Sbjct: 4329 AKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREF 4388 Query: 1934 DEIIFRISAENTVGVSLPT 1952 ++ FR+ A N G +P+ Sbjct: 4389 NDYEFRVVAINAAGKGIPS 4407 Score = 199 bits (485), Expect = 8e-49 Identities = 198/749 (26%), Positives = 306/749 (40%), Gaps = 52/749 (6%) Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILD---KPSPPGKPNILE 1391 +D + +L + + N ++++ NN G ++ + I D +P PG+P I + Sbjct: 833 VDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITD 892 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 D+ I+I W+ P G + I Y+VE ++ DT EW VK + T SI LK Y+F Sbjct: 893 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQF 952 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 R AVN+ SE +E ++ K I + LK+IT + + GG P P Sbjct: 953 RVRAVNKAGPGQPSEPSE-KQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIP 1011 Query: 1512 KVTWYRDGKKLKTA-KATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 +V W++ ++L+ + T + R Y+ N HG E + Sbjct: 1012 EVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLT 1071 Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKE 1625 + +P + N ++ D ++ E I Y KL+ + K Sbjct: 1072 VLDRP--SKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKV 1129 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMREIS 1679 K + I LK+ + ++ ++A N G S T K YD+P K P ++ + Sbjct: 1130 KDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVV-DWD 1188 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 + V++EW+PP DGG +T+Y IEK W + V D I L E EY F Sbjct: 1189 ADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILGLKEGEEYQF 1248 Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 RV A N G EA + S +V K P ID E++ + K G Sbjct: 1249 RVKAVNKAGPGEASDPSRKVVAKPRNLKP----------WIDREAMKTI---TIKVGNDV 1295 Query: 1799 IIDYKVEIKQEGKK-WKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852 D V + KK W RI+ T + R R G T+ + Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355 Query: 1853 SDDKITIGK-TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 DK ++ L PS P VS L+W PE +GG+PI +Y IE + Sbjct: 1356 GSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATG 1415 Query: 1911 SWTKIVTVGGS-VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSP 1968 W V G S + + N++ E FR+ A N G S P + + L K+ VP Sbjct: 1416 RW---VPCGRSETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGK 1472 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 P E+ + V +W P+ DGGAP+ + I +D W E V + + Sbjct: 1473 VDKP-ELVDWDKDHVDLAWNAPD-DGGAPIEAFVIEKKD-KNGRWEEALVVPGDQKTATV 1529 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDE 2057 +L E Y RI ARN+ G +P + + Sbjct: 1530 PNLKEGEEYQFRISARNKAGTGDPSDPSD 1558 Score = 191 bits (465), Expect = 2e-46 Identities = 201/860 (23%), Positives = 347/860 (40%), Gaps = 56/860 (6%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286 W + ++D +K + S+ K ++R T YT +A + K VEV+ Sbjct: 1311 WIFNEKPVDD-QKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGSDKHSVEVIVLGK 1369 Query: 1287 ---PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 P ++ Y + +D+ V P D + + + + P S++ Sbjct: 1370 PSSPLGPLEVSNVYEDR--ADLEWKVPEDDGGAPIDHYEIEKMDLATGRWV-PCGRSETT 1426 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397 T+ ++ +++R N G +D + N IL K P KP +++ D + Sbjct: 1427 KTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDKDHV 1486 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 ++ W+ P++ G + I +V+E ++ + E + V KT T + NLK Y+FR A Sbjct: 1487 DLAWNAPDD-GGAPIEAFVIEKKDKNGRWEEALVVPGDQKTAT-VPNLKEGEEYQFRISA 1544 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVT 1514 N+ D S+ ++ +V+ + + +P + + L + T + ++ G P P VT Sbjct: 1545 RNKAGTGDPSDPSD--RVVAKPRNLAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVT 1602 Query: 1515 WYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 W +GK + +KA EN Y A N +G + + ++ KP Sbjct: 1603 WSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNINGTDSVTINIKVKSKP 1662 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWYKNGNKLENDKEYNITTKEK 1626 K +V D + A ++ PP + + +Y+ D + + Sbjct: 1663 T------KPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVPCGRSG 1716 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLK-VYDKPSKPEGPVIMREISR 1680 + + L + K+ ++A N+ G S ++ K +D+P +P P + Sbjct: 1717 DTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGRPE-PTDWDS 1775 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 + V ++W PPL DGG + +Y IEK RW V T + L N EY FR Sbjct: 1776 DHVDLKWDPPLSDGGAPIEEYQIEK-RTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFR 1834 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 V+A N G S+ ++ VI ++ I++ +P + Sbjct: 1835 VVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTV 1894 Query: 1801 DYKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 + +E G + K ++++ + F I A N G + KI Sbjct: 1895 TWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGED---EATVKI 1951 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIV 1916 + T P+ P + VS+ VTL W P+ +GG PI NY+IE + T G+ W Sbjct: 1952 NVIDKPTSPNGPLD--VSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDTASGR-WVPAA 2008 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEI 1975 V G ++ + E FR++A N G S P E+ L K P AP EI Sbjct: 2009 KVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAP-EI 2067 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + V W P DGGAP+ Y + ++D W +V V + +L E Sbjct: 2068 TDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGS 2127 Query: 2036 TYMIRIYARNEIGLSEPLES 2055 Y RI A+N+ GL +P +S Sbjct: 2128 KYEFRIRAKNKAGLGDPSDS 2147 Score = 190 bits (463), Expect = 4e-46 Identities = 195/754 (25%), Positives = 321/754 (42%), Gaps = 57/754 (7%) Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEI- 1392 P + S +A T++ +E+ +++R EN G +D V ++ K PPG P+ EI Sbjct: 3476 PGLISGTA-YTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEIT 3534 Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISVKN--ITKTQTSIQNLKTNS 1447 D++ +++ W+ P + G S I+ YVVE +++ +W VK + T+ + L N Sbjct: 3535 GYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHENE 3594 Query: 1448 SYRFRAYAVNEVDISDASETTEYYK----VIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 +Y+FR AVN + S +E V K +P V K KN + E + L Sbjct: 3595 TYQFRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRD 3653 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENR-----XXXXXXXXXXXXXXXYKCIAFNDHGE 1558 GG P + + KKL T N ++ IA N GE Sbjct: 3654 --GGAPIDG--YIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGE 3709 Query: 1559 VETSC---VVGIQQ---KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 E S +V I++ +P+ I+N +DI + G+ + G P +I NGN Sbjct: 3710 GEPSKPSDLVLIEEQPGRPIFDINNLKDITVR--AGETIQIRIPYAGGNPKPIIDLFNGN 3767 Query: 1612 K--LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 EN++ + VI KRS + Y I A+N G + ++ + V D P KP Sbjct: 3768 SPIFENERTV-VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKP 3826 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 GP+ +I +++T+ W+PP D+GG +T Y +EK P + W+ V T ++ Sbjct: 3827 TGPIRATDIQADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVG--TTLRVR 3883 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 L+ N Y FRV A+N G E LE+ + IV K D P E++ + W Sbjct: 3884 NLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAVET-SEEAITLQW 3942 Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEI 1845 +GG+PI Y +E ++ G +W R+ L+ TY+FR+ A N Sbjct: 3943 TRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAA 4002 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKWTEPESNGGSPITNYIIEF 1904 G + IT T P + + + K P + +P + Sbjct: 4003 GQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGE 4062 Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 + V + IE + D ++ + EN+ G ++S S+RL+ Sbjct: 4063 NKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG----SDSASIRLK---- 4114 Query: 1965 VPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVD 2020 V P +P IR+ + + W P DGG+P+ Y + D+ + W +V Sbjct: 4115 VVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSF- 4173 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 V L + + L +++ Y R+ A + G+SEP E Sbjct: 4174 VRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCE 4207 Score = 183 bits (445), Expect = 5e-44 Identities = 179/738 (24%), Positives = 296/738 (40%), Gaps = 41/738 (5%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397 S+T+ K+ +++ EN G +D + + +L K P PG+P I++ D+ I Sbjct: 3191 SITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTDNDHI 3250 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 +I WD P + G S + +Y +E ++ T WI V + T S ++ +Y +R A Sbjct: 3251 DIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHTYEYRVVA 3310 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKV 1513 VN+ S+++ + ++P + L K + E + +T F PQP + Sbjct: 3311 VNKAGPGQPSDSSA--AATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPDI 3368 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 +W ++G K T +++ K A N +GE E + + + KP Sbjct: 3369 SWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKITVIDKPGA 3428 Query: 1574 TIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIR 1631 + +H W G E+ YK + + ++ + + Sbjct: 3429 PENITYPAVSRHTCTLNWDAPKDDGGA---EIAGYKIEYQEVGSQIWDKVPGLISGTAYT 3485 Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLK-VYDKPSKPEGPVIMREISRESVTIE 1686 ++ L+ ++ I A N G S V V +K +D P P P I + + V++ Sbjct: 3486 VRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQ-VSLA 3544 Query: 1687 WKPPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744 W PP DDGG + Y +E+ E W V + T CI L+EN Y FRV A Sbjct: 3545 WNPPRDDGGSPILGYVVERFEKRGGGDWAPVK-MPMVKGTECIVPGLHENETYQFRVRAV 3603 Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G E SEP+ + ++ P N S +TW ++GG+PI Y Sbjct: 3604 NAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKN-SAELTWNRPLRDGGAPIDGYI 3662 Query: 1804 VEIKQEGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 VE K+ G W ++ L Y+FR+ A N G P D + I Sbjct: 3663 VEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIE 3722 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVG 1919 + P N + + T++ P + G PI + + T +V V Sbjct: 3723 EQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENERT-VVDVN 3781 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 K D ++ISA N G + V P PT P+ + Sbjct: 3782 PGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFV-----LDAPGKPTGPIRATDIQ 3836 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 ++ + SW P+ +GG + Y + R W+ VG TL+ +R+L N Y Sbjct: 3837 ADAMTLSWRPPKDNGGDAITNYVVEKRTPGGD-WVTVGHPVGTTLR--VRNLDANTPYEF 3893 Query: 2040 RIYARNEIGLSEPLESDE 2057 R+ A N+ G+ EPLE+D+ Sbjct: 3894 RVRAENQYGVGEPLETDD 3911 Score = 178 bits (434), Expect = 1e-42 Identities = 177/708 (25%), Positives = 273/708 (38%), Gaps = 47/708 (6%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 D P P KP + + D I+I W+ N G + + Y+VE +E + W T Sbjct: 2939 DVPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTF 2998 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 S NLK Y FR AVN SD S+ T+ I + + P + + I + Sbjct: 2999 SADNLKPGVEYEFRVIAVNAAGPSDPSDPTD--PQITKARYLKPKILTASRKIKIKAGFT 3056 Query: 1499 IELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXYKCIAFN 1554 L F G P P TW D + + + YK N Sbjct: 3057 HNLEVDFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKN 3116 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + GE E V +Q +P + +V D + V+ PP + + N + Sbjct: 3117 ELGEDEAIFEVIVQDRPSAP------EGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVV 3170 Query: 1615 NDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK-- 1665 ++ T S I + +L H ++ + A NT G S S+ V K Sbjct: 3171 EKRDTKTNTWVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDP 3230 Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P KP P I+ + + + I+W PP D+GG + Y IE+ + RWIKV Sbjct: 3231 FGTPGKPGRPEIV-DTDNDHIDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQ 3289 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXXXXXXI-- 1779 + ++ + Y +RV+A N G + +S K + P Sbjct: 3290 GTAFSDTRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVK 3349 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQF 1837 E + IT P SP D + +EG K + I + + Sbjct: 3350 AGEPLVIT-IPFT---ASPQPD--ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPV 3403 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 +I A N G + ++ KIT+ + P P N + + TL W P+ +GG+ I Sbjct: 3404 KIKAVNPYGEA---EANIKITV---IDKPGAPENITYPAVSRHTCTLNWDAPKDDGGAEI 3457 Query: 1898 TNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 Y IE++ V + W K+ + G+ + + ++ + FRI AEN VG+S + Sbjct: 3458 AGYKIEYQEVGSQIWDKVPGLISGTAYT--VRGLEHGQQYRFRIRAENAVGLSDYCQGVP 3515 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-IRDVTKTMWME 2015 V ++ P P+ P EI +N V +W P DGG+P+LGY + W Sbjct: 3516 VVIKDPFDPPGAPSTP-EITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAP 3574 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 V V + + L EN TY R+ A N G EP EP P Sbjct: 3575 VKMPMVKGTECIVPGLHENETYQFRVRAVNAAGHGEPSNGSEPVTCRP 3622 Score = 176 bits (428), Expect = 6e-42 Identities = 168/684 (24%), Positives = 283/684 (41%), Gaps = 42/684 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P+I+ + ++ +A F E + + RW ++G E+ S+ + K I Sbjct: 4423 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTI 4482 Query: 1166 YDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTV 1218 + DAGEY+ EV G+ TA L V+ P + +P IL + Y + Sbjct: 4483 KEVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPV-IEKDVPNTILPSGDLVRLKIYFSG 4541 Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 P V ++ + T + D T+ E + EYT ++TT Sbjct: 4542 TAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTG 4601 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 + V P + I T + ++ P + + S +++K +K Sbjct: 4602 FWLNVTGLPEAP---QGPLHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKD-- 4655 Query: 1339 DSKSASLTIKKVENTDAGI-----YKLRL----ENNCGHADVEMNVTILDKP-SPPGKP- 1387 + + + +K + G+ Y+ R+ EN G V + I P PP P Sbjct: 4656 EWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPL 4715 Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNL 1443 I+++ + + W P + G + Y+VE QE + EW + + NL Sbjct: 4716 NLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNL 4775 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 YR+R +AVN+ +SD +E + + + P + PL ++ E + C Sbjct: 4776 IDGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSG-EGPKIVSPLSDLNEEVGRCVTFEC 4834 Query: 1504 IFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEV 1559 G P+P+ W++ K+L T+K T N+ Y C A N G Sbjct: 4835 EISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTR 4894 Query: 1560 ETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 T + I+ KP + I + + + G+ + + P E W K+G K+EN+ + Sbjct: 4895 STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSK 4954 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 ++ITT +K + +RI R +Y + N+ G+ S V + V D P P P+I I Sbjct: 4955 FSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPEPPRFPII-ENI 5013 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEY 1737 E+V + WKPP DGG +T Y IEK E W A + TY I+ L +Y Sbjct: 5014 LDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCA---KSRYTYTTIEGLRAGKQY 5070 Query: 1738 MFRVIAQNPVGFSEALE-SEPIVI 1760 FR+IA+N G S+ E + P++I Sbjct: 5071 EFRIIAENKHGQSKPCEPTAPVLI 5094 Score = 171 bits (416), Expect = 2e-40 Identities = 173/731 (23%), Positives = 285/731 (38%), Gaps = 49/731 (6%) Query: 1358 YKLRLENNCGHADVEMN---VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++R N GH + VT ++KP P P + +I +S + W+ P G + Sbjct: 3598 FRVRAVNAAGHGEPSNGSEPVTCRPYVEKPGAPDAPRVGKITKNSAELTWNRPLRDGGAP 3657 Query: 1412 IIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I Y+VE +++ +W K + T ++NL Y FR AVN + S+ ++ Sbjct: 3658 IDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSD 3717 Query: 1470 YYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF-GGVPQPKVTWYRDGKKL----K 1523 V+ E + P + LK+IT E I++ + GG P+P + + + + Sbjct: 3718 L--VLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIFENER 3775 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDI 1580 T YK A N +G+ V+ KP I DI Sbjct: 3776 TVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDI 3835 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 Q + W G + I K ++ + +R++ L + Sbjct: 3836 -QADAMTLSWRPPKDNGG----DAITNYVVEKRTPGGDWVTVGHPVGTTLRVRNLDANTP 3890 Query: 1641 SKYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 ++ + A N G T V +D P P P + E S E++T++W P DG Sbjct: 3891 YEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQPEAV-ETSEEAITLQWTRPTSDG 3949 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-AL 1753 G + Y IEK E + W K A + + + L Y FRV A N G E ++ Sbjct: 3950 GAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLTPKKTYEFRVAAYNAAGQGEYSV 4009 Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV---EIKQEG 1810 S PI A P + +P + + +I Sbjct: 4010 NSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPAPKVTFSKGENKISPTD 4069 Query: 1811 KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 + K I+K + + + N G SD K + P+ P+ Sbjct: 4070 PRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQG------SDSASIRLKVVDKPASPQ 4123 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIE 1928 + V + TL W P S+GGSPITNYI+E ++ W K+ + +++ + + Sbjct: 4124 HIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLN-YTVG 4182 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSW 1987 + + + FR+ AE GVS P E V + K+ VP+ P AP +R S W Sbjct: 4183 GLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAP-TVRDKDSTWAELEW 4241 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYARNE 2046 P DGG+ ++GY + RD + W+ K+D++ + L +N + RI A+N Sbjct: 4242 DPPR-DGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQCHARVTGLRQNGEFEFRIIAKNA 4299 Query: 2047 IGLSEPLESDE 2057 G S+P E Sbjct: 4300 AGFSKPSPPSE 4310 Score = 163 bits (396), Expect = 5e-38 Identities = 171/752 (22%), Positives = 289/752 (38%), Gaps = 47/752 (6%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLE--NNCGHADVEMNVTILDKP--SPPGKP---NILE 1391 ++K +K ++ + G YK R++ N CG +D ++L K PGKP + ++ Sbjct: 537 ETKGTDFKVKDLK--EHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKNMDAID 594 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSY 1449 +D + W+ PE G + I Y++E +E +W V + + K + Y Sbjct: 595 VDKDHCTLAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEY 654 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 +R AVN+ D + + K+ K K +K++ + E I+ G P Sbjct: 655 LYRVKAVNKAGPGDPCDHGKPIKM-KAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEP 713 Query: 1510 QPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P+ W +GK LK ++ + + N G +++ V Sbjct: 714 LPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATV 773 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624 + +P DI G + P + ++N +Y K Sbjct: 774 TVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKV 833 Query: 1625 -EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMRE 1677 T+ +++ L+ + K+ ++A N G S S + ++ +D+P KP P I + Sbjct: 834 DPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEIT-D 892 Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 + + I W+PP DGG + +Y +E +PD W +V V D I L E EY Sbjct: 893 FDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRVP-DTNA-SISGLKEGKEY 950 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV A N G + E + +P+ + W K GG Sbjct: 951 QFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVRW--EVKIGGE 1008 Query: 1798 PIIDYK-----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 PI + K +++ + I + ++R+ +N G Sbjct: 1009 PIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGAD---- 1064 Query: 1853 SDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGK 1910 ++K + L PS+P VS+ ++ L W P+ +GG PI Y +E T G+ Sbjct: 1065 -EEKANL-TVLDRPSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVEKLDTATGR 1122 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 W V + H I+ +K+ FR+ A N G S + K+ T Sbjct: 1123 -WVPCAKVKDT-KAH-IDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKT 1179 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 ++ ++ V W P+ DGGAP+ Y I + W E GKV + I Sbjct: 1180 GTPDVVDWDADRVSLEWEPPKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQTNAEILG 1239 Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 L E Y R+ A N+ G E SD KV+ Sbjct: 1240 LKEGEEYQFRVKAVNKAGPGE--ASDPSRKVV 1269 Score = 142 bits (343), Expect = 1e-31 Identities = 121/481 (25%), Positives = 196/481 (40%), Gaps = 20/481 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438 P PP I + I W P G S I Y VE +E +T W S N+ + + Sbjct: 4321 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEF 4380 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NE 1497 ++ L+ + Y FR A+N S + K+ + + V KP T +P N Sbjct: 4381 TVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKP--EDTAQPYNR 4438 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXX---XXXXYKCIAF 1553 TC G P+P W R+G++L ++++ +E Y Sbjct: 4439 RAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVS 4498 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N +G + + +Q PVI +D+ GD + G P N + Sbjct: 4499 NPYGSDTATANLVVQAPPVI---EKDVPNTILPSGDLVRLKIYFSGTAPFRHSLVLNREE 4555 Query: 1613 LENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 ++ D I + +I I L + +Y SN +G ++ L V P P+G Sbjct: 4556 IDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAPQG 4615 Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731 P+ + I + T+ W+PP+ DGG ++T Y +EK + + W+ V +D+ Y + L Sbjct: 4616 PLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDM-NYIVTGL 4674 Query: 1732 NENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 EN EY FRV AQN G L SE PI+ + D P + + V ++W Sbjct: 4675 FENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFD-PPTSPLNLEIVQVGGDYVTLSWQR 4733 Query: 1791 SEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXX--XXARIQKLSINTTYQFRIYARNEIGT 1847 +GG + Y VE ++E +W + L Y++R++A N+ G Sbjct: 4734 PLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAGL 4793 Query: 1848 S 1848 S Sbjct: 4794 S 4794 Score = 132 bits (320), Expect = 8e-29 Identities = 148/640 (23%), Positives = 256/640 (40%), Gaps = 48/640 (7%) Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 K T KL V V++ P K R I+ + + + ++ P+ N + + +++K Sbjct: 3810 KDTCKLNVFVLDAPGKPTGPIRATDIQADA---MTLSWRP-PKDNGGDAITNYVVEKRTP 3865 Query: 1334 TKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHAD-VEMNVTIL-----DKPSPP 1384 + T +V N DA +++R EN G + +E + I+ D P P Sbjct: 3866 GGDWVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAP 3925 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQN 1442 G+P +E +I + W P + G + I YV+E +E+ +TEW NI T+ + Sbjct: 3926 GQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTG 3985 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL--KNITTEPNEDIE 1500 L +Y FR A N + S + + + P + + ++I E + Sbjct: 3986 LTPKKTYEFRVAAYNAAGQGEYSVNS--VPITADNAPTRPKINMGMLTRDILAYAGERAK 4043 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLK----TAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555 + F P PKVT+ + K+ K Y + Y N Sbjct: 4044 ILVPFAASPAPKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENS 4103 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGN 1611 G S + + KP S + I+ + D W+ + G P I K Sbjct: 4104 QGSDSASIRLKVVDKPA---SPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDL 4160 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665 + + K +++ + + L + + ++ + A G S V V ++ Sbjct: 4161 RHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEV 4220 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P++PE P + R+ +EW PP DGG ++ Y ++ + + RWI A +D + Sbjct: 4221 PNQPEAPTV-RDKDSTWAELEWDPP-RDGGSKIIGYQVQYRDTSSGRWIN-AKMDLSEQC 4277 Query: 1726 YC-IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + + L +N E+ FR+IA+N GFS+ + SE +K+ P I Sbjct: 4278 HARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFG-PPGPPIHVGAKSIGRNH 4336 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840 ITW ++GGS I Y VEI++ G W + KL Y+FR+ Sbjct: 4337 CTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVV 4396 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 A N G +P I I + + S+P+ V E T++ Sbjct: 4397 AINAAGKGIPSLPSGPIKIQE--SGGSRPQIVVKPEDTAQ 4434 Score = 129 bits (311), Expect = 9e-28 Identities = 147/608 (24%), Positives = 233/608 (38%), Gaps = 43/608 (7%) Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425 C ADV + + P+ P P + + DS+ + WD P + G S II Y V+Y++ + Sbjct: 4206 CELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQYRDTSSG 4264 Query: 1426 EWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 WI+ K Q + L+ N + FR A N S S +E ++ P Sbjct: 4265 RWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP 4324 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RD-GKKLKTAKATYENRX-XXXX 1537 + K+I + + G K+T Y R+ G L T + Y R Sbjct: 4325 IHVGAKSIGRNHCTITWMAPLEDG--GSKITGYNVEIREYGSTLWTVASDYNVREPEFTV 4382 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQQ----KPVITISNEDIKQKHKVGDEW 1590 ++ +A N G+ S G IQ+ +P I + ED Q + + Sbjct: 4383 DKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVF 4442 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 AV G P P W +NG +L Y + IKE+ + +YT+E SN Sbjct: 4443 TCEAV--GRPEPTARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNP 4500 Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 G+ + L V P PVI +++ TI L G L K P Sbjct: 4501 YGSDTATANL-VVQAP-----PVIEKDVPN---TI-----LPSGDLVRLKIYFSGTAPFR 4546 Query: 1711 NRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA---LDV 1766 + + ++D D T I + +++ ++ G E S T L+V Sbjct: 4547 HSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNV 4606 Query: 1767 ---PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822 P I + ++W P +GGS I Y VE + K +W Sbjct: 4607 TGLPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKD 4666 Query: 1823 XARIQK-LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 I L N Y+FR+ A+NE G P S+ I PP+ P N + + Sbjct: 4667 MNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDY 4726 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 VTL W P S+GG + YI+E + + W + + + + N+ + + +R+ Sbjct: 4727 VTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVF 4786 Query: 1942 AENTVGVS 1949 A N G+S Sbjct: 4787 AVNDAGLS 4794 Score = 124 bits (299), Expect = 3e-26 Identities = 79/288 (27%), Positives = 126/288 (43%), Gaps = 13/288 (4%) Query: 1788 WFPSEKNGGSPIIDY---KVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 W P +GGSPI +Y K++++ KW K + L + Y+FR+ A Sbjct: 4139 WMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRYRFRVRAET 4198 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 + G S P D + P+QP V + S L+W +P +GGS I Y ++ Sbjct: 4199 QYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEW-DPPRDGGSKIIGYQVQ 4257 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959 ++ W + + E C + +++ E FRI A+N G S P+ S+ +L Sbjct: 4258 YRDTSSGRW---INAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQL 4314 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 + P PP + + +G N +W P DGG+ + GYN+ IR+ T+W Sbjct: 4315 KSRFGPPGPPIH-VGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDY 4373 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS 2067 +V +F + L E + Y R+ A N G P P K+ GS Sbjct: 4374 NVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 4421 Score = 99 bits (238), Expect = 7e-19 Identities = 80/341 (23%), Positives = 142/341 (41%), Gaps = 11/341 (3%) Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P I WY++ + I + +N+ +I N D+G Y C A+ G +H Sbjct: 45 PNAKIRWYKDRKEIFSGGLKYKIVIEKNVCTLIINNPEVDDTGKYTCEAN---GVPTHAQ 101 Query: 920 RVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977 ++ K +F+ L + E K +L C+ + WY K I D R II+ Sbjct: 102 LTVLEPPMKYSFLNPLPNTQEIYRTKQAVLTCKVNTPRAPLVWYRGSKAIQEGDPRFIIE 161 Query: 978 E---GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034 + GR I +D + + V+E F+ ++ +V E D+A Sbjct: 162 KDAVGRCTLTIKEVEEDDQAEWTARITQDVFSKVQVYVEEPRHTFVVPMKSQKVNESDLA 221 Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 LE ++N + A+VVW DG+ I K+ E R+L I + D GEY C +D+ Sbjct: 222 TLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIEDHGEYKCTTKDD 281 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF--SNHI 1152 A++ +V+ + I L++ +V + + T + WF++G +I Sbjct: 282 RTMAQL-IVDAKNKFIVALKDTEVIEKDDVTLMCQTKDTKTPGIWFRNGKQISSMPGGKF 340 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 + LKI ++++A Y + + + +TV E Sbjct: 341 ETQSRNGTHTLKIGKIEMNEADVYEIDQAGLRGSCNVTVLE 381 Score = 99.1 bits (236), Expect = 1e-18 Identities = 55/197 (27%), Positives = 102/197 (51%), Gaps = 4/197 (2%) Query: 1866 PSQPRNFVVSES-TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P P+ + +++ T+ + L W P+ + G+P+ YIIE + + +W K+ G+ + Sbjct: 485 PKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVGETKGT--D 542 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 ++++KE E FR+ A N G+S P +SV + VP P ++ V + Sbjct: 543 FKVKDLKEHGEYKFRVKALNECGLSDPLTGESVLAKNPYGVPGKPKN-MDAIDVDKDHCT 601 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 +W PE DGGAP+ GY I R+ ++ W +VG+ + + + + E+ Y+ R+ A Sbjct: 602 LAWEPPEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAV 661 Query: 2045 NEIGLSEPLESDEPFKV 2061 N+ G +P + +P K+ Sbjct: 662 NKAGPGDPCDHGKPIKM 678 Score = 98.3 bits (234), Expect = 2e-18 Identities = 62/198 (31%), Positives = 97/198 (48%), Gaps = 11/198 (5%) Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIK 1931 +S + TL W P ++GGS IT+Y++E + + W VTV +V + + + + Sbjct: 4619 ISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEW---VTVTSNVKDMNYIVTGLF 4675 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAP--LEIRMVGSNIVMTSWG 1988 E E FR+SA+N G+ P S+ + A +P PPT+P LEI VG + V SW Sbjct: 4676 ENHEYEFRVSAQNENGIGAPLVSEHPII---ARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 4732 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P DGG L GY + ++ W + +N+ +L + Y R++A N+ G Sbjct: 4733 RPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLIDGRKYRYRVFAVNDAG 4792 Query: 2049 LSEPLESDEPFKVIPGEG 2066 LS+ E D+ G G Sbjct: 4793 LSDLAELDQTLFQASGSG 4810 Score = 94.3 bits (224), Expect = 3e-17 Identities = 105/463 (22%), Positives = 176/463 (38%), Gaps = 27/463 (5%) Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKV-YDKP 1666 L D+ +T+ K + L +H ++ + A N G S + ++ +D P Sbjct: 4652 LSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPP 4711 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 + P I+ ++ + VT+ W+ PL DGG L Y +EK E +++ W + Y Sbjct: 4712 TSPLNLEIV-QVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNY 4770 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L + +Y +RV A N G S+ E + + + A ++ E Sbjct: 4771 NVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLFQ-ASGSGEGPKIVSPLSDLNEEVGRC 4829 Query: 1787 TWFPSEKNGGSPIIDYK----VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 F E + GSP +Y+ + + K+ I L+ + ++ A Sbjct: 4830 VTFECEIS-GSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRAT 4888 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 N GT + T + PP + + T++ P + Sbjct: 4889 NSSGTRSTRANLRIKTKPRVFIPPKYHGGY----EAQKGETIELKIPYKAYPQGEARWTK 4944 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + + ++ S I T I N +D +R+ EN+VG T + +V Sbjct: 4945 DGEKIENNSKFSI-TTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTV----- 4998 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 A VP PP P+ I + V+ SW P DGG+ + Y I R+ W K Sbjct: 4999 ADVPEPPRFPI-IENILDEAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYT 5057 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065 I L Y RI A N+ G S+P E P +IPG+ Sbjct: 5058 YT--TIEGLRAGKQYEFRIIAENKHGQSKPCEPTAPV-LIPGD 5097 Score = 89.8 bits (213), Expect = 7e-16 Identities = 79/324 (24%), Positives = 133/324 (41%), Gaps = 20/324 (6%) Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820 T LDVP I E + W P NGG+ ++ Y VE + W+ Sbjct: 2836 TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGTFP 2895 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 A++ KL Y FR+ A N G S P +++ I P V++ Sbjct: 2896 DCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVTDWDKD 2955 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 + +KW +NGG+P+T YI+E K WT+ G+ +N+K E FR+ Sbjct: 2956 RIDIKWNPTANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFS--ADNLKPGVEYEFRV 3013 Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGA 1996 A N G S P++ ++ K + P TA +I++ N+ + G P+ Sbjct: 3014 IAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPD----- 3068 Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 P + + + V K ++ F +++ Y +++ +NE+G E Sbjct: 3069 PTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKV--KNELG-----ED 3121 Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079 + F+VI + A E P E ++V Sbjct: 3122 EAIFEVIVQDRPSAPEGPLEVSDV 3145 Score = 88.6 bits (210), Expect = 2e-15 Identities = 123/580 (21%), Positives = 216/580 (37%), Gaps = 52/580 (8%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTH 787 E +P +++P + V +G+S +V+ + P +TW K+++ +K + +G+ + Sbjct: 5472 EAQPRFIVKPYGTE-VGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDY 5530 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 +TI + K D+G YT++A+NS G E + V +E PL E K Sbjct: 5531 GLTINRVKG-DDKGEYTVRAKNSYGTKEEIVFLNVTRHSEPLKFEPL------EPMKKAP 5583 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYK 905 ++ R P T++ N +I + +T + G + D D Sbjct: 5584 SPPRVEEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRV 5643 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK 965 V+ S S +D + T+ + + V+ TV TK Sbjct: 5644 QVSFRSGVCSLEIFNARVD-DAGTYTVTATNDLGVDVSECVL-------TVQTKGGEPIP 5695 Query: 966 EISGMDHR---EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET--IPEF 1019 +S R + + G +I+ + D + + L K T +P F Sbjct: 5696 RVSSFRPRRAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSF 5755 Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 +L D E + A ++ + ++ W +GE I +++ L I + Sbjct: 5756 TAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLRISD 5815 Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV--------------VELPPEIITRLQNQKVNK 1120 DEG+Y C + E A +TV VE + L + VN Sbjct: 5816 AKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNN 5875 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 G TFE + V W ++G E+ + ++ DG+ I D DAG Y EV Sbjct: 5876 GESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEV 5935 Query: 1181 GNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234 + +++ V E + RLP + P T+E + E L V W++ Sbjct: 5936 RSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFRGSE 5995 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 IE E+ + L I+ +DD Y ++ K Sbjct: 5996 KIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEK 6035 Score = 87.8 bits (208), Expect = 3e-15 Identities = 67/257 (26%), Positives = 108/257 (42%), Gaps = 9/257 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P PE W+K +L + +Y + K V+ I +L + +YT A+N++GT S Sbjct: 4836 ISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSGTRS 4895 Query: 1656 VEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 L++ KP P +++ TIE K P ++ + + +NN Sbjct: 4896 TRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 + D+ T I + +RV+ +N VG V T DVP Sbjct: 4956 SITTDDK-FATLRISNASREDYGEYRVVVENSVGSDSGT-----VNVTVADVPEPPRFPI 5009 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQKLSINT 1833 +D E+V ++W P +GGS + +Y +E ++ G W I+ L Sbjct: 5010 IENILD-EAVILSWKPPALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGK 5068 Query: 1834 TYQFRIYARNEIGTSLP 1850 Y+FRI A N+ G S P Sbjct: 5069 QYEFRIIAENKHGQSKP 5085 Score = 70.5 bits (165), Expect = 5e-10 Identities = 33/94 (35%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024 +P P PL I +G + SW P DGG+ + Y + RD++K W+ V +V + Sbjct: 4609 LPEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTS-NVKDM 4667 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + L ENH Y R+ A+NE G+ PL S+ P Sbjct: 4668 NYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHP 4701 Score = 70.5 bits (165), Expect = 5e-10 Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 16/224 (7%) Query: 708 YTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 Y V AVN G A L L +G E P+++ PL + G V ++ G+PRP Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842 Query: 765 TITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 W CK + GD + I+ D YT +A NS G T A + Sbjct: 4843 EYRWFKGCKELVDTSKYTLINKGD-KQVLIINDLTSDDADEYTCRATNSSGTRSTRANLR 4901 Query: 822 VEEPTEENAEPPLFI-NRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETI 879 ++ +P +FI ++ +KG TI+L P W ++ E I + Sbjct: 4902 IK------TKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKF 4955 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + D + L I+N E D G+Y+ V NS G S VT+ Sbjct: 4956 SITTDDKFATLRISNASRE-DYGEYRVVVENSVGSDSGTVNVTV 4998 Score = 66.9 bits (156), Expect = 6e-09 Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 15/233 (6%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+ K +G + F C+V P +TW + +K S + Y+ ++ L Sbjct: 5475 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYG-LT 5533 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I V +D G +T AKN+ G T E IV ++ H + + Sbjct: 5534 INRVKGDDKGEYTVRAKNSYG----TKEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVE 5589 Query: 630 E----GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 E P F+ + + + + L C L P P I W+ G V ++ + V+ Sbjct: 5590 EFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHP-VDEDRVQVSFR 5648 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP-PQV 737 S + CS L+I N + GTYTV A N G VL ++T EP P+V Sbjct: 5649 SGV---CS-LEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRV 5697 Score = 66.5 bits (155), Expect = 8e-09 Identities = 71/286 (24%), Positives = 111/286 (38%), Gaps = 26/286 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+F+ + + G + PEP I WL GE I ++ + + Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDS---RFRASYVAGKA 5809 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-----------KEPPQVIEPLK 742 L+I++ KK EG Y A N G+ L +K + + +V + L Sbjct: 5810 TLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLG 5869 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKD 799 IV GESV A+V G P + W +N + + DG+T S TI D Sbjct: 5870 GEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTI-NSADASD 5927 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTR 858 G Y L+ S+G S V E A+PP + R ++ G+ Sbjct: 5928 AGHYQLEV-RSKGTNLVSVASLV--VVGEKADPP--VTRLPSSVSAPLGGSTAFTIEFEN 5982 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 ++ W+R +E I +E + G +L I NV+ + D G Y Sbjct: 5983 VEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQD-DDGIY 6027 Score = 62.9 bits (146), Expect = 9e-08 Identities = 63/288 (21%), Positives = 114/288 (39%), Gaps = 17/288 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD--THSIT 790 E P L G S SA V G P P I W N + + ++ T Sbjct: 5751 ELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKAT 5810 Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITV--EEP-----TEENAEPPLFINRFQEI 842 + + K DEG Y +A NS G +T A +TV ++P + E L + + Sbjct: 5811 LRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGG 5870 Query: 843 TVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + G ++ ARV P + W RN + ++ + + + DGE + I + D+ D+ Sbjct: 5871 EIVNNGESVTFEARVQGTP-EEVLWMRNGQELTNGDKTSISQDGETLSFTINSADAS-DA 5928 Query: 902 GDYKC-VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVST 958 G Y+ V S S + V + + V L S G + +E + ++ Sbjct: 5929 GHYQLEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTV 5988 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IKCIVKDQE 1005 +W+ ++I + + ++ G D G+ + +VK+++ Sbjct: 5989 QWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKEKK 6036 Score = 62.9 bits (146), Expect = 9e-08 Identities = 69/318 (21%), Positives = 123/318 (38%), Gaps = 32/318 (10%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATL 568 P F +L T G + +F V G P P I W I S F+ Y ATL Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGK-ATL 5811 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXXXXXXXXA 626 I + D G + C A N+AG + L V + PL + + V Sbjct: 5812 RISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESEL--------- 5862 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 +K + V+ G + E R+ PE ++ W+ G+E+ + S++ + Sbjct: 5863 --------RVTKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDG 5913 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + + I + G Y + V +G + + + GEK P V S+ Sbjct: 5914 ETLSF----TINSADASDAGHYQ-LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSA 5968 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803 G S + + T+ W + ++ + + + + G+T + I K + D+G+Y Sbjct: 5969 PLGGSTAFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDI-KNVEQDDDGIY 6027 Query: 804 TLK-AENSEGIAETSAVI 820 K + + IA+ +A + Sbjct: 6028 VAKVVKEKKAIAKYAAAL 6045 Score = 61.7 bits (143), Expect = 2e-07 Identities = 71/268 (26%), Positives = 107/268 (39%), Gaps = 24/268 (8%) Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 VE E D W R + P N Y+ RK R +V+D G D++ Sbjct: 4747 VEKQEEEHDE-WFRCNQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGLSDLAELDQTLF 4804 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 E P+I++ L + G TFE E++ RWFK E+ ++ L Sbjct: 4805 QASGSGE-GPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLIN 4863 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP------- 1209 G KQ L I D DDA EY+C NS T N ++ + +P Sbjct: 4864 KGDKQVLIINDLTSDDADEYTCRATNSSGT-----RSTRANLRIKTKPRVFIPPKYHGGY 4918 Query: 1210 -ANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 A + ++IP + + W K IE+ KF++ +D K TL I + +D E Sbjct: 4919 EAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGE 4978 Query: 1266 YTCVLLDA----KSTTKLKVEVVEFPPK 1289 Y V+ ++ T + V V PP+ Sbjct: 4979 YRVVVENSVGSDSGTVNVTVADVPEPPR 5006 Score = 54.8 bits (126), Expect = 2e-05 Identities = 40/135 (29%), Positives = 70/135 (51%), Gaps = 11/135 (8%) Query: 704 QEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 +E + VVAVN+ G +AS ++ K + +P + LK++ ++ G+S+ V Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRN--LKPHIDRDALKNLTIKAGQSISFDVPV 1886 Query: 759 VGNPRPTITW-CKNNKPVK-ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G P PT+TW +N+ ++ K D + S ++K + D G +T+KA N+ G E Sbjct: 1887 SGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDE 1946 Query: 816 TSAVITV-EEPTEEN 829 + I V ++PT N Sbjct: 1947 ATVKINVIDKPTSPN 1961 Score = 53.6 bits (123), Expect = 6e-05 Identities = 42/223 (18%), Positives = 95/223 (42%), Gaps = 9/223 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y + A N G+++ + + + E P ++ ++ + + ++ +P P Sbjct: 4783 YRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRP 4842 Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 W++ E++ S+ N G+ L+I ++ S+ D+ +Y C A+NS+G S A + Sbjct: 4843 EYRWFKGCKELVDTSKYTLIN-KGDKQVLIINDLTSD-DADEYTCRATNSSGTRSTRANL 4900 Query: 922 TIDVEKVTFV-KHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE 978 I + F+ YE ++G+T+ L+ + +W + ++I I + Sbjct: 4901 RIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENNSKFSITTD 4960 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPE 1018 + D G + +V++ ++ T+ V +PE Sbjct: 4961 DKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVPE 5003 Score = 52.8 bits (121), Expect = 1e-04 Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%) Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVR 747 C L V + +E Y V AVN+ G P +K+K + P +K + ++ Sbjct: 640 CCELTDKKVVEDKEYLYRVKAVNKAGPGD-PCDHGKPIKMKAKKASPEFTGGGIKDLRLK 698 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805 GE++ + G P P W N KP+KA+ I+K + D G +T+ Sbjct: 699 VGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 758 Query: 806 KAENSEGIAETSAVITV 822 +NS G +++A +TV Sbjct: 759 TLKNSSGSCDSTATVTV 775 Score = 52.4 bits (120), Expect = 1e-04 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P V L + G V FEC++ G PRP+ WF+ + + + + D L+ Sbjct: 4813 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDK-QVLI 4871 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I ++ +DA +TC A N++G S+ L ++ Sbjct: 4872 INDLTSDDADEYTCRATNSSGTRSTRANLRIK 4903 Score = 50.4 bits (115), Expect = 5e-04 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 5/136 (3%) Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752 +I +K+ +E + V AVN+ G EAS P + P + E +K++ ++ G V Sbjct: 1236 EILGLKEGEEYQFRVKAVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDV 1295 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSE 811 V G P P W N KPV + + + + +L+ K G+YTL A N+ Sbjct: 1296 EFDVPVRGEPPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNAS 1355 Query: 812 GIAETSA-VITVEEPT 826 G + S VI + +P+ Sbjct: 1356 GSDKHSVEVIVLGKPS 1371 Score = 50.4 bits (115), Expect = 5e-04 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 1/112 (0%) Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 I LP E P V K P F C+ G P P W R + Sbjct: 4405 IPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELP 4464 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 S ++ + D V I+EV+ DAG +T N G ++T L+V+AP Sbjct: 4465 ESSRYR-FEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVVQAP 4515 Score = 50.0 bits (114), Expect = 7e-04 Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 7/140 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753 I+ +K+ +E + V AVN+ G + S P ++ + P + + LKS+ V+ G +V Sbjct: 941 ISGLKEGKEYQFRVRAVNKAGPGQPSEPSEKQLAKPKFIPAWLKHDNLKSITVKAGATVR 1000 Query: 754 LSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 ++ G P P + W K N+ ++ L + + H+I + D G Y L +NS Sbjct: 1001 WEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLTVKNS 1060 Query: 811 EGIAETSAVITV-EEPTEEN 829 G E A +TV + P++ N Sbjct: 1061 HGADEEKANLTVLDRPSKPN 1080 Score = 49.6 bits (113), Expect = 0.001 Identities = 49/215 (22%), Positives = 91/215 (42%), Gaps = 23/215 (10%) Query: 1476 ETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATY 1529 +TKI + P+ L + TE E + G P+P + W +G+++ + +A+Y Sbjct: 5745 KTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASY 5804 Query: 1530 -ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVIT------ISNEDIK 1581 + Y C A N G+ +T + ++ +P++ + +E Sbjct: 5805 VAGKATLRISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRV 5864 Query: 1582 QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 KH G+ A ++G P EV+W +NG +L N + +I+ +T I Sbjct: 5865 TKHLGGEIVNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSA 5923 Query: 1636 KRSHSSKYTIEASNTAGTSSVEV-TLKVYDKPSKP 1669 S + Y +E + GT+ V V +L V + + P Sbjct: 5924 DASDAGHYQLEV-RSKGTNLVSVASLVVVGEKADP 5957 Score = 49.2 bits (112), Expect = 0.001 Identities = 55/275 (20%), Positives = 100/275 (36%), Gaps = 23/275 (8%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164 P +L + + G A F ++ + + L+ W +G I S+ + + K L+ Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 5812 Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTV--EEPSIN--------FTLRLPEFI---L 1207 I D D G+Y C NS + A LTV ++P +N LR+ + + + Sbjct: 5813 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEI 5872 Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 V + +V W + + + +K ++ D + + I D Y Sbjct: 5873 VNNGESVTFEARVQGTPEEVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQ 5932 Query: 1268 CVL----LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 + + S L V + P + G ++++ +W Sbjct: 5933 LEVRSKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGSTAFTIEFENVEGLTVQWFR 5992 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 S+ I+K + K + L IK VE D GIY Sbjct: 5993 GSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIY 6027 Score = 48.8 bits (111), Expect = 0.002 Identities = 36/149 (24%), Positives = 66/149 (44%), Gaps = 9/149 (6%) Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEP 740 + SD ++ + +++F + + VVA+N G+ SLP +KI+ PQ++ Sbjct: 4369 VASDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVK 4428 Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKK 796 + + + + VG P PT W +N + + SDG + TI + Sbjct: 4429 PEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDG-VYKFTIKEVWD 4487 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEP 825 + D G YT++ N G +A + V+ P Sbjct: 4488 I-DAGEYTVEVSNPYGSDTATANLVVQAP 4515 Score = 48.4 bits (110), Expect = 0.002 Identities = 32/121 (26%), Positives = 48/121 (39%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + +KA N G + S + P + + F VK T+ V P P Sbjct: 2424 FRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPAP 2483 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 I W+ N +S + + +N + T + DSG YK VA+N +GK H V Sbjct: 2484 KIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVDVN 2543 Query: 923 I 923 I Sbjct: 2544 I 2544 Score = 47.6 bits (108), Expect = 0.004 Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 8/130 (6%) Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPL--KSMIVRQGESVI 753 T V+K Y VVAVN+ G T + E P+ L K V+ GE ++ Sbjct: 3296 TRVQKGHTYEYRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLV 3355 Query: 754 LSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ +P+P I+W K KP+ + T D+ + ++ + D G +KA N G Sbjct: 3356 ITIPFTASPQPDISWTKEGGKPLAGVETT---DSQTKLVIPSTRRSDSGPVKIKAVNPYG 3412 Query: 813 IAETSAVITV 822 AE + ITV Sbjct: 3413 EAEANIKITV 3422 Score = 47.2 bits (107), Expect = 0.005 Identities = 45/163 (27%), Positives = 73/163 (44%), Gaps = 25/163 (15%) Query: 770 KNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 K K VK +P DT+ SI+ LK K E + ++A N G + S EP+E+ Sbjct: 926 KEWKEVKRVP-----DTNASISGLKEGK---EYQFRVRAVNKAGPGQPS------EPSEK 971 Query: 829 NAEPPLFI------NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 P FI + + ITVK T++ ++ P+P + W++ N+ + +T Sbjct: 972 QLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLT-- 1029 Query: 883 FDGENIELVITNVDSEI--DSGDYKCVASNSAGKSSHGARVTI 923 D E I + S + D G+Y+ NS G A +T+ Sbjct: 1030 IDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTV 1072 Score = 46.8 bits (106), Expect = 0.007 Identities = 50/195 (25%), Positives = 80/195 (41%), Gaps = 21/195 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 G + EC + P P+ W FKG +E+V ++ + D VL I ++ Sbjct: 4827 GRCVTFECEISGSPRPEYRW-FKGCKELVDTSKYTLINKGDK----QVLIINDLTSDDAD 4881 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763 YT A N G S L+IKT P+V P K ++GE++ L P+ Sbjct: 4882 EYTCRATNSSGTRSTRANLRIKT----KPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQ 4937 Query: 764 PTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 W K+ + ++ +D ++ I + +D G Y + ENS G + + Sbjct: 4938 GEARWTKDGEKIENNSKFSITTDDKFATLRISNASR-EDYGEYRVVVENSVGSDSGTVNV 4996 Query: 821 TVEEPTEENAEPPLF 835 TV + EPP F Sbjct: 4997 TVADV----PEPPRF 5007 Score = 46.4 bits (105), Expect = 0.009 Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 4/130 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVIL 754 + N+K+ + + + A N+ G + P VI+ ++ + V+ G+ L Sbjct: 2120 VGNLKEGSKYEFRIRAKNKAGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSL 2179 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812 + V G P PTITW PV++ + T K+ D G Y +KAEN G Sbjct: 2180 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 2239 Query: 813 IAETSAVITV 822 +TV Sbjct: 2240 TDTAEVKVTV 2249 Score = 46.4 bits (105), Expect = 0.009 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 4/121 (3%) Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARV 856 K+E + + A NS G E S + E+ P IN ++ITV+ TI++ + Sbjct: 3694 KEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIRIPYA 3753 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKS 915 NP P I + N I +E D E+VIT S+ D+G YK A+N GK Sbjct: 3754 GGNPKPIIDLFNGNSPIFENERTV--VDVNPGEIVITTTGSKRSDAGPYKISATNKYGKD 3811 Query: 916 S 916 + Sbjct: 3812 T 3812 Score = 45.2 bits (102), Expect = 0.020 Identities = 50/176 (28%), Positives = 70/176 (39%), Gaps = 11/176 (6%) Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P PD+ W F G+ I + IE++ Y S + + Q G YT+ A N G S Sbjct: 1597 PAPDVTWSFNGKGIGESK---AQIENEP--YISRFALPKALRKQSGKYTITATNINGTDS 1651 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALP 779 + I +K+K+ +P IE R G P K N K +P Sbjct: 1652 VTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWVP 1711 Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA---ETSAVITVEEPTEENAEP 832 GDTH T+ K D + +KA NSEG + ET I + P + P Sbjct: 1712 CGRSGDTH-FTVDSLNK-GDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRP 1765 Score = 43.6 bits (98), Expect = 0.061 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVI 753 + N+K+ +E + + A N+ G + S P + P++ E L V+ G ++ Sbjct: 1529 VPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGATLK 1588 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEG 812 + G P P +TW N K + + + + + PK + K G YT+ A N G Sbjct: 1589 FIVHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALPKALRKQSGKYTITATNING 1648 Query: 813 IAETSAVITVE-EPTE 827 + I V+ +PT+ Sbjct: 1649 TDSVTINIKVKSKPTK 1664 Score = 43.6 bits (98), Expect = 0.061 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 4/130 (3%) Query: 699 NVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 N+K E + V+AVN G + S P +I P+++ + + ++ G + L Sbjct: 3002 NLKPGVEYEFRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEV 3061 Query: 757 QVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814 +G P PT TW + P D + + +I P K D G Y LK +N G Sbjct: 3062 DFIGAPDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGED 3121 Query: 815 ETSAVITVEE 824 E + V++ Sbjct: 3122 EAIFEVIVQD 3131 Score = 43.6 bits (98), Expect = 0.061 Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 6/126 (4%) Query: 693 SVLKITNVKKFQEGTYTVVAVNR--EGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQG 749 + ++ N+ + +E + V+AVN EGE S P ++ I+ P I LK + VR G Sbjct: 3684 TAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAG 3743 Query: 750 ESV-ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTLK 806 E++ I GNP+P I N P+ + T D + I I K D G Y + Sbjct: 3744 ETIQIRIPYAGGNPKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKIS 3803 Query: 807 AENSEG 812 A N G Sbjct: 3804 ATNKYG 3809 Score = 42.7 bits (96), Expect = 0.11 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Query: 482 QYLQKKLNEKIDKLPVFEKPT--SEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPR 538 Q+ K LN+ + P T ++ + +AP I + + G T+ F+ VEG P Sbjct: 2423 QFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNFDVNVEGEPA 2482 Query: 539 PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 P+I WF + + + + + DN L + D+G + VA N +G Sbjct: 2483 PKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESG 2534 Score = 41.9 bits (94), Expect = 0.19 Identities = 33/122 (27%), Positives = 51/122 (41%), Gaps = 4/122 (3%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + ++A+N G+ + S + N P + N QEI VK L V+ P P Sbjct: 2131 FRIRAKNKAGLGDPSDSASAVAKAR-NVPPVIDRNSIQEIKVKAGQDFSLNIPVSGEPTP 2189 Query: 863 SITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 +ITW + + S N DG+ V + S D+G Y A N G + +V Sbjct: 2190 TITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRS--DTGTYIIKAENENGTDTAEVKV 2247 Query: 922 TI 923 T+ Sbjct: 2248 TV 2249 Score = 41.5 bits (93), Expect = 0.25 Identities = 39/157 (24%), Positives = 60/157 (38%), Gaps = 9/157 (5%) Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 KN + +AL D T ++ LK +E + + A N G + S N Sbjct: 1510 KNGRWEEALVVPGDQKTATVPNLKEG---EEYQFRISARNKAGTGDPSDPSDRVVAKPRN 1566 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 P + + TVK T+K + + P P +TW N + I S+ +N I Sbjct: 1567 LAPRIHREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIGESKAQIEN--EPYIS 1624 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 SG Y A+N G S VTI+++ Sbjct: 1625 RFALPKALRKQSGKYTITATNINGTDS----VTINIK 1657 Score = 41.1 bits (92), Expect = 0.33 Identities = 24/87 (27%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 G ++ F+ V G P P +TW + I+ ++ + + + LV++++ D+GTFT Sbjct: 1877 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLD-NPEYQSKLVVKQMERGDSGTFT 1935 Query: 583 CVAKNAAGFASSTTEL-IVEAPLSDHG 608 A NA G +T ++ +++ P S +G Sbjct: 1936 IKAVNANGEDEATVKINVIDKPTSPNG 1962 Score = 40.7 bits (91), Expect = 0.43 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T++ + + YP+ + W + I+ + F + DD ATL I ED G + Sbjct: 4923 GETIELKIPYKAYPQGEARWTKDGEKIENNSKFSIT-TDDKFATLRISNASREDYGEYRV 4981 Query: 584 VAKNAAGFASSTTELIV 600 V +N+ G S T + V Sbjct: 4982 VVENSVGSDSGTVNVTV 4998 Score = 40.3 bits (90), Expect = 0.57 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ AP F LR + + C ++G P P I W + + +D Sbjct: 5592 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPV--DEDRVQVSFRS 5649 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 V +L I +DAGT+T A N G S L V+ Sbjct: 5650 GVCSLEIFNARVDDAGTYTVTATNDLGVDVSECVLTVQ 5687 Score = 39.9 bits (89), Expect = 0.75 Identities = 61/286 (21%), Positives = 103/286 (36%), Gaps = 17/286 (5%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P KP+ + C V PEP WL G E+ E+ E+ + Sbjct: 4420 GSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGREL--PESSRYRFEASDGV 4477 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 Y +K V G YTV N G + L ++ PP + + + + I+ G+ Sbjct: 4478 YKFTIK--EVWDIDAGEYTVEVSNPYGSDTATANLVVQA----PPVIEKDVPNTILPSGD 4531 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807 V L G + N + + PT + D H + + V++ G Y Sbjct: 4532 LVRLKIYFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTV 4591 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G A T + V E + PL I+ T T+ VT ++ Sbjct: 4592 SNDSGEATTGFWLNV-TGLPEAPQGPLHISNIGPST----ATLSWRPPVTDGGSKITSYV 4646 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +S E +T + +++ ++T + E +++ A N G Sbjct: 4647 VEKRDLSKDEWVTVTSNVKDMNYIVTGL-FENHEYEFRVSAQNENG 4691 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-LVIREVFPEDAGTFT 582 G+ V+F+ V G P P+ W KP D ++ + ++ T V+R + AG +T Sbjct: 1292 GNDVEFDVPVRGEPPPKKEWIFNE---KPVDDQKIRIESEDYKTRFVLRGATRKHAGLYT 1348 Query: 583 CVAKNAAGFASSTTELIV 600 A NA+G + E+IV Sbjct: 1349 LTATNASGSDKHSVEVIV 1366 Score = 39.1 bits (87), Expect = 1.3 Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T ++G P P + W K+G+ ++ D+ ++ + + I + + YT+ A+N Sbjct: 5617 LTCSLQGNPNPTIEWMKDGHPVDEDR-VQVSFRSGVCSLEIFNARVDDAGTYTVTATNDL 5675 Query: 1652 GTSSVEVTLKVYDKPSKP 1669 G E L V K +P Sbjct: 5676 GVDVSECVLTVQTKGGEP 5693 Score = 38.3 bits (85), Expect = 2.3 Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 6/132 (4%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVI 753 + +K Q + V A+N+ GE+ S P + P++ + + V+ G+++ Sbjct: 2413 VDGLKPGQTYQFRVKALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLN 2472 Query: 754 LSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810 V G P P I W N P+ + T D +T + T L K D G Y + A N Sbjct: 2473 FDVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNE 2532 Query: 811 EGIAETSAVITV 822 G E + + Sbjct: 2533 SGKDEHEVDVNI 2544 Score = 37.5 bits (83), Expect = 4.0 Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 10/152 (6%) Query: 781 KSDGDTHSITILKP--------KKVKD-EGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 KS+ D H + KP K V+D E +Y +KA N G + + + A Sbjct: 625 KSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGDPCDHGKPIKMKAKKAS 684 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P +++ +K TIK ++ P+P W N + + + + + + Sbjct: 685 PEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMK 744 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 I N DSG + NS+G A VT+ Sbjct: 745 IENA-VRADSGKFTITLKNSSGSCDSTATVTV 775 Score = 37.1 bits (82), Expect = 5.3 Identities = 41/183 (22%), Positives = 76/183 (41%), Gaps = 22/183 (12%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G VT Q P+ W+ N + + T S D ++ S TI + +DAG Y Sbjct: 5873 VNNGESVTFEARVQGTPE-EVLWMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHY 5931 Query: 1359 KLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 +L + + V V + +K PP + + SS P G ST + + Sbjct: 5932 QLEVRSKGTNLVSVASLVVVGEKADPP----VTRLPSSV-----SAP--LGGSTA--FTI 5978 Query: 1418 EYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 E++ ++ T +W + ++++KT ++++ V + D + KV+K Sbjct: 5979 EFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDD-----DGIYVAKVVK 6033 Query: 1476 ETK 1478 E K Sbjct: 6034 EKK 6036 Score = 36.7 bits (81), Expect = 7.0 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 5/133 (3%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +E + + A N G ++ S N +P + + + +T+K +I V+ Sbjct: 1829 EEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSG 1888 Query: 859 NPVPSITWY--RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P++TW+ N EI + N + ++ +LV+ ++ DSG + A N+ G+ Sbjct: 1889 EPAPTVTWHWPDNREIRNGGRVKLDNPEYQS-KLVVKQMERG-DSGTFTIKAVNANGEDE 1946 Query: 917 HGARVTIDVEKVT 929 ++ + ++K T Sbjct: 1947 ATVKINV-IDKPT 1958 Score = 36.7 bits (81), Expect = 7.0 Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 3/86 (3%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX---XXXXXXXXXXX 1544 L+N + N +LTC G P P + W +DG + + R Sbjct: 5604 LRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGVCSLEIFNARVDD 5663 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK 1570 Y A ND G + CV+ +Q K Sbjct: 5664 AGTYTVTATNDLGVDVSECVLTVQTK 5689 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/113 (22%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Query: 503 SEEQSMAPIFV------EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 SE+Q P F+ + L+ G+TV++E ++ G P P++ WF+ ++ Sbjct: 969 SEKQLAKPKFIPAWLKHDNLKSITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQL 1028 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHG 608 + + L I D G + KN+ G L +++ P +G Sbjct: 1029 TIDTRKNEHTILCIPSAMRSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNG 1081 >UniRef50_Q7YT99 Cluster: Twitchin; n=4; Mollusca|Rep: Twitchin - Mytilus galloprovincialis (Mediterranean mussel) Length = 4736 Score = 315 bits (773), Expect = 1e-83 Identities = 278/1162 (23%), Positives = 486/1162 (41%), Gaps = 49/1162 (4%) Query: 930 FVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 ++ L TE K I E + KW+ NK EI + Sbjct: 1099 YIVELDDVKATEGDKKAIFESEFCKKNAKVKWFKNKLEIFAGHKYHFENDNMKYRLVVNN 1158 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQD--FEVKEKDVAILEVEINSET 1044 D G + ++ L V+ P EF +KL + + K K+V LE ++ Sbjct: 1159 VKLEDGGKYTLELNGVKSGAWLYVEAKAPHVEFTQKLPEKFSQTKRKEVD-LECFVSDPR 1217 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A V W ++G+ I+ + K + ++R + L I++ DE EY+C D T + V + Sbjct: 1218 ARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTCGDAKTTCQFKVTD 1277 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 + + L + + + ++ATFE ++ +A V+W ++ E+ ++ +DG K++L Sbjct: 1278 PEWDFMKLLDDVEGIERDRATFECDVNDPEAEVKWSRNDKELTSGGKYEIQVDGFKRRLV 1337 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 + +C D G Y+C+V + + TA L V EP + F +L T Sbjct: 1338 VKNCHSKDDGPYTCKVLDKETTANLFV-EPDVKFFKKLENKREREKGTLVLECKASNPHN 1396 Query: 1225 LDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 V W K + + +D + + + ++I+ T +D +Y C + + S ++ V+ Sbjct: 1397 QPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLTREDAGQYACQVGERSSKWEVIVDE 1456 Query: 1284 VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + PP+I D E +K+G + + + + P P+ W + + + T + Sbjct: 1457 LPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMPSGHWKKDGNPLSEA-DTDIRMTDT 1515 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINIC 1400 AS+ I + D G Y+L L N G + + V +LD P PG+P +++++ + + Sbjct: 1516 LASIRIPDAQRGDTGQYELTLTNEVGSEVIPIPVRVLDVPGRPGEPLDVVDVFADKCALL 1575 Query: 1401 WDEPENTGNSTIIYYVVEYQ--EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 WD P++ G S I +Y+VE + E D+ + V + + LK Y+FR AVNE Sbjct: 1576 WDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQVCTTEDLEVDVTGLKEGHRYQFRVRAVNE 1635 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL----TCIFGGVPQPKVT 1514 S+ + + K+ P+ N+ + +E+ GG P K Sbjct: 1636 QGTSEPL-LADGEIIAKDP--WDPSDPPQDTNVEDYDKDYVEIGWKPPISDGGAPIEKYV 1692 Query: 1515 WYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGI 1567 + K E ++ ++ A N G+ E T V+ Sbjct: 1693 IEKCEKHRPEWVPGIEVPGDKRAGTVSGLTENREYIFRVSAVNKAGKSEPSEATPPVLTK 1752 Query: 1568 QQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNG-----NKLENDKEYN 1620 ++ I N+D + +V G ++ + G P P++ W K G LE + Sbjct: 1753 SRRVRPRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHIS 1812 Query: 1621 ITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 I K EK S + KE R ++ Y + +N G+ + +V + V PS P+GP+ + I+ Sbjct: 1813 IDNKTEKKSTLTCKEPSRKDTAMYNVTVTNKHGSDTADVEVVVLGPPSMPKGPIKVSNIT 1872 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 ES T+EW P D GG + Y +EK + +W V + + + + KL E EY F Sbjct: 1873 AESATLEWGEPEDLGGSPIDGYKVEKMDTKKGQWEPVREGVKGTKV-TVPKLKEGQEYKF 1931 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 RV A + G SE LE++PI+ K D P D + + W P E +GG P+ Sbjct: 1932 RVAAMSQNGNSEPLETKPIIAKKPYDEPFPPGQPKCVDR-DRTHIKMKWEPPENDGGYPV 1990 Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 Y VE K+ + +W K+ Y++R+ A N+ G S P + Sbjct: 1991 NSYDVERKEPKTNRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKV 2050 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTVKGKSWTKI 1915 I P + + + R + + P G+P E + K Sbjct: 2051 IQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAKC 2110 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + H ++ + D + I+ N G S+ + + L+K P P PL + Sbjct: 2111 TSSEEDAKLH-VDKAERGDTGKYTITVTNESG-SMSADVNVIVLDK----PGAPEGPLAV 2164 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 V +++ SW P +GGA + GY + + K W +V + VN ++ L E Sbjct: 2165 SDVFADMCRLSWNPPADNGGAEVTGYVVEKCEDGKDFWEKVPGL-VNGTAHPVKGLKEGK 2223 Query: 2036 TYMIRIYARNEIGLSEPLESDE 2057 Y R+ A N+ G PLE+D+ Sbjct: 2224 KYKFRVKAENKYGAGAPLETDK 2245 Score = 275 bits (674), Expect = 1e-71 Identities = 309/1257 (24%), Positives = 515/1257 (40%), Gaps = 94/1257 (7%) Query: 864 ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W++N EI + + +N D LV+ NV E D G Y + KS V Sbjct: 1128 VKWFKNKLEIFAGHKYHFEN-DNMKYRLVVNNVKLE-DGGKYTLELNGV--KSGAWLYVE 1183 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR-EIIQEGR 980 V F + L + + + K V LEC S KW+ N + I + EI + Sbjct: 1184 AKAPHVEFTQKLPEKFSQTKRKEVDLECFVSDPRARVKWFKNGQPIEYQSGKMEIQRREN 1243 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D C D +T+ V + +F++ L D E E+D A E ++ Sbjct: 1244 RCILRIKDCQPDDEAEYTCTCGDAKTTCQFKVTDPEWDFMKLLDDVEGIERDRATFECDV 1303 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 N A+V W R+ + + KY+ + G R+L ++N D+G Y+C + D+ TA + Sbjct: 1304 NDPEAEVKWSRNDKELT-SGGKYEIQVDGFKRRLVVKNCHSKDDGPYTCKVLDKETTANL 1362 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSN-HIQLTIDG 1158 VE + +L+N++ + E + + + V+W KDG I + +++T G Sbjct: 1363 -FVEPDVKFFKKLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKG 1421 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDA 1214 + K+ I + +DAG+Y+C+VG + V+E P IN +PE I+V Sbjct: 1422 ELYKIVIKNLTREDAGQYACQVGERSSKWEVIVDELPKPPQIN-AKDIPEEIIVKKGE-- 1478 Query: 1215 YLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 + + IP + + W K + + + + ++D ++ I D +Y L Sbjct: 1479 VIEIGIPFIGVPMPSGHWKKDGNPLSEADTDIRMTDTLA-SIRIPDAQRGDTGQYELTL- 1536 Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT-LLVDYQA--FPQPNDEWIVNSK-I 1327 T ++ EV+ P +++D R DV + D A + +P D+ K Sbjct: 1537 ----TNEVGSEVIPIPVRVLDVPG--RPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHY 1590 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGI-------YKLRLENNCGH-----ADVEMNV 1375 I + K ++ D T + +E G+ +++R N G AD E+ Sbjct: 1591 IVEMKDSEKDSDRFEQVCTTEDLEVDVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIA 1650 Query: 1376 TILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434 PS PP N+ + D + I W P + G + I YV+E E EW+ + Sbjct: 1651 KDPWDPSDPPQDTNVEDYDKDYVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVP 1710 Query: 1435 --KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNI 1491 K ++ L N Y FR AVN+ S+ SE T + K +++ + K LK I Sbjct: 1711 GDKRAGTVSGLTENREYIFRVSAVNKAGKSEPSEATPPV-LTKSRRVRPRIMNKDDLKPI 1769 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDG--KKLKTAKAT--------YENRXXXXXXXXX 1541 + +D + + G P PK+ W + G KK + + + E + Sbjct: 1770 RVKVGKDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPS 1829 Query: 1542 XXXXXXYKCIAFNDHG----EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y N HG +VE V+G P I +I + EW + Sbjct: 1830 RKDTAMYNVTVTNKHGSDTADVEV-VVLGPPSMPKGPIKVSNITAESATL-EWGEPEDLG 1887 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 G P + YK K++ K +E K + + + +LK K+ + A + G S Sbjct: 1888 GSP---IDGYKV-EKMDTKKGQWEPVREGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSE 1943 Query: 1656 -VE----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 +E + K YD+P P P + + R + ++W+PP +DGG + Y +E+ EP Sbjct: 1944 PLETKPIIAKKPYDEPFPPGQPKCV-DRDRTHIKMKWEPPENDGGYPVNSYDVERKEPKT 2002 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS- 1768 NRW K+ Y K+ + EY +RV+A N G SE ++ S+ I K + P Sbjct: 2003 NRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKV 2062 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827 I ++ P +G +P + ++ + + K + Sbjct: 2063 SLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAKCTSSEEDAKLHVD 2122 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKW 1886 K T ++ I NE G+ ++D + + L P P VS+ + L W Sbjct: 2123 KAERGDTGKYTITVTNESGS---MSADVNVIV---LDKPGAPEGPLAVSDVFADMCRLSW 2176 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKS-WTKIV-TVGGSVHEHCIENIKEKDEIIFRISAEN 1944 P NGG+ +T Y++E K GK W K+ V G+ H ++ +KE + FR+ AEN Sbjct: 2177 NPPADNGGAEVTGYVVE-KCEDGKDFWEKVPGLVNGTAHP--VKGLKEGKKYKFRVKAEN 2233 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 G P E+ L K+ LEI N W P++DGGA + GY + Sbjct: 2234 KYGAGAPLETDKSILAKNPFDTPDAPKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIVE 2293 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 R W+ V + KF+ L E R+ A N+ +P +S +P V Sbjct: 2294 KRPKGGD-WVPVNNFPLADTKFSALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTV 2349 Score = 248 bits (607), Expect = 1e-63 Identities = 248/992 (25%), Positives = 395/992 (39%), Gaps = 62/992 (6%) Query: 1104 ELPPEIITRLQNQKVNKGNK-ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E P + I L + K +G+K A FE E K +A V+WFK+ EI + D K + Sbjct: 1094 EKPDKYIVELDDVKATEGDKKAIFESEFCKKNAKVKWFKNKLEIFAGHKYHFENDNMKYR 1153 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEI 1220 L + + L+D G+Y+ E+ K A L VE P + FT +LPE + L + Sbjct: 1154 LVVNNVKLEDGGKYTLELNGVKSGAWLYVEAKAPHVEFTQKLPEKFSQTKRKEVDLECFV 1213 Query: 1221 PDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 D V W+K IE + K + + L I+ C DD+ EYTC DAK+T + Sbjct: 1214 SDPRARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTCGDAKTTCQF 1273 Query: 1280 KVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 KV E+ K++D R + + D P+ +W N K + + + Sbjct: 1274 KVTDPEWDFMKLLDDVEGIERDRATFECDVND----PEAEVKWSRNDKELTSGGKYEIQV 1329 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 D L +K + D G Y C D E + +P D Sbjct: 1330 DGFKRRLVVKNCHSKDDGPY------TCKVLDKETTANLFVEP-----------DVKFFK 1372 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457 ++ E + ++ +W+ + I K ++ + Y+ + Sbjct: 1373 KLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLT 1432 Query: 1458 EVDISD----ASETTEYYKVIKETKIQSPTVE-KPL-KNITTEPNEDIELTCIFGGVPQP 1511 D E + ++VI + + P + K + + I + E IE+ F GVP P Sbjct: 1433 REDAGQYACQVGERSSKWEVIVDELPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMP 1492 Query: 1512 KVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 W +DG L A + Y+ N+ G V + Sbjct: 1493 SGHWKKDGNPLSEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVGSEVIPIPVRVL 1552 Query: 1569 QKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 P D+ K W G P I ++ ++D+ + T E Sbjct: 1553 DVPGRPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQVCTTED 1612 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSV-----EVTLKVYDKPSKPEGPVIMREISRE 1681 V + LK H ++ + A N GTS E+ K PS P + + ++ Sbjct: 1613 LEV-DVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIAKDPWDPSDPPQDTNVEDYDKD 1671 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 V I WKPP+ DGG + KY IEK E W+ +V D + L EN EY+FRV Sbjct: 1672 YVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVPGDKRAGTVSGLTENREYIFRV 1731 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG-SPII 1800 A N G SE E+ P V+ + V I + P E G +P I Sbjct: 1732 SAVNKAGKSEPSEATPPVLTKSRRVRPRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKI 1791 Query: 1801 DYK---VEIKQEGKKWKXXXXXXXXXARIQKL-----SINTTYQFRIYARNEIGTSLPYT 1852 ++K ++ K+E + + L S T + + N+ G+ T Sbjct: 1792 EWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSRKDTAMYNVTVTNKHGSD---T 1848 Query: 1853 SDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 +D ++ + L PPS P+ + VS T+ S TL+W EPE GGSPI Y +E K Sbjct: 1849 ADVEVVV---LGPPSMPKGPIKVSNITAESATLEWGEPEDLGGSPIDGYKVEKMDTKKGQ 1905 Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971 W V G + + +KE E FR++A + G S P E++ + +K P PP Sbjct: 1906 WEP-VREGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSEPLETKPIIAKKPYDEPFPPGQ 1964 Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031 P + ++I M W PE DGG P+ Y++ ++ W ++ K + T +++ + Sbjct: 1965 PKCVDRDRTHIKM-KWEPPENDGGYPVNSYDVERKEPKTNRWAKINKEPITTCEYDDNKV 2023 Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + Y R+ A N+ G SEP + + + P Sbjct: 2024 GKEKEYEYRVVAINDAGPSEPSVASKVIQAKP 2055 Score = 237 bits (579), Expect = 3e-60 Identities = 191/705 (27%), Positives = 305/705 (43%), Gaps = 32/705 (4%) Query: 1288 PKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS----IDSK 1341 P+I++ + + R+K G D T+ V+Y P P EW + KK + +PS ID+K Sbjct: 1758 PRIMNKDDLKPIRVKVGKDFTIPVEYIGEPTPKIEW-KKKGLDKKEEPLEPSDHISIDNK 1816 Query: 1342 S---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSI 1397 + ++LT K+ D +Y + + N G ++ V +L PS P P + I + S Sbjct: 1817 TEKKSTLTCKEPSRKDTAMYNVTVTNKHGSDTADVEVVVLGPPSMPKGPIKVSNITAESA 1876 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456 + W EPE+ G S I Y VE + +W V+ K T+ ++ LK Y+FR A+ Sbjct: 1877 TLEWGEPEDLGGSPIDGYKVEKMDTKKGQWEPVREGVKGTKVTVPKLKEGQEYKFRVAAM 1936 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 ++ S+ ET + P K + T E GG P Sbjct: 1937 SQNGNSEPLETKPIIAKKPYDEPFPPGQPKCVDRDRTHIKMKWEPPENDGGYPVNSYDVE 1996 Query: 1517 R-DGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKP- 1571 R + K + AK E Y+ +A ND G E S IQ KP Sbjct: 1997 RKEPKTNRWAKINKEPITTCEYDDNKVGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPE 2056 Query: 1572 --VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 +S + + + + K G+ + + G P P V W KNG ++N + T+ E Sbjct: 2057 KEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGTPTPTVSWEKNGRPVDNRAK--CTSSE 2114 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 + + + + + +R + KYTI +N +G+ S +V + V DKP PEGP+ + ++ + + Sbjct: 2115 EDAKLHVDKAERGDTGKYTITVTNESGSMSADVNVIVLDKPGAPEGPLAVSDVFADMCRL 2174 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 W PP D+GG E+T Y +EK E + W KV + + ++ L E +Y FRV A+N Sbjct: 2175 SWNPPADNGGAEVTGYVVEKCEDGKDFWEKVPGLVNGT-AHPVKGLKEGKKYKFRVKAEN 2233 Query: 1746 PVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 G LE++ I+ K D P D S + W + +GG+ I Y V Sbjct: 2234 KYGAGAPLETDKSILAKNPFDTPD-APKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIV 2292 Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 E + +G W + L + +FR+ A N+ T P S T+ Sbjct: 2293 EKRPKGGDWVPVNNFPLADTKFSALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTVKDP 2352 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 + P + + T S L WT+P +GG I Y IE K G W V + Sbjct: 2353 IFAAGAPGTPNLDKITPNSAELSWTKPTKDGGGKILGYFIEKKKGHG-DWETATEVPANA 2411 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 + ++ E ++ FRI A N G P++ +Q++ E A P Sbjct: 2412 LHGKVNDLVEGEQYQFRIRAINEAGPGDPSKPTQAITAEYQAEKP 2456 Score = 219 bits (535), Expect = 7e-55 Identities = 180/699 (25%), Positives = 300/699 (42%), Gaps = 35/699 (5%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ +K+G + V Y+A+ +P+ W ++ + + ++ ++ LT K + D Sbjct: 2464 KDITVKQGQKYQIRVPYKAWLKPSALWTIDEEELPSVARIHTKVEDEAVMLTNDKSQRAD 2523 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTII 1413 +G YK+ L N G+ +NV +L P+ P P +I+ + + W P++ G I Sbjct: 2524 SGKYKITLTNPSGNHSGFVNVNVLSPPAKPEGPFTASDINGDELTLSWGAPKDDGGEKIS 2583 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 Y++E ++ + +W V K T ++NL+ + Y FR A N IS ET + Sbjct: 2584 NYIIERKKKGSPKWSKVTGTAKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDK--A 2641 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNED-IELTCI-----FGGVPQPKVTWYRDGKKLKTAK 1526 ++ + +P K + E ED I LT G + + V ++ K K Sbjct: 2642 ILAKLPYDTPGAPGTPKCL--EYTEDSITLTWTPPKNDGGNIIKGYVVEKKEKGKPDWTK 2699 Query: 1527 ATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGE---VETSCVVGIQQKPVITISNEDIK 1581 A + Y + A N+ G +TS + + PV ++ Sbjct: 2700 ANISDILTNEFQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFT 2759 Query: 1582 QKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKR 1637 + KVG+ + + G P P+ W L E D+ T + ++ K K Sbjct: 2760 PRDVIAKVGEPFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKE 2819 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 + +YT+ N G ++ + + V DKPSKPEGP+ +++ +S T+ W P DDGG Sbjct: 2820 D-AGRYTLTMKNEKGQDTIALNVVVVDKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSP 2878 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-E 1756 ++ Y +EK + RW V+ R + Y + L+E EY FRV A+N G SE LE E Sbjct: 2879 VSNYVVEKCDTRTGRWEPVSKFVRGAK-YEVMGLDEGHEYKFRVSAENENGVSEPLEVLE 2937 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815 P++ + P +D +SV + + +GG I Y VE K +WK Sbjct: 2938 PVLAQHPYTAPGSPSNVHVLD-VDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKM 2996 Query: 1816 XXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR--N 1871 + + L + Y+FR+ A+N G P D I T P Sbjct: 2997 HNDIASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKPKYTLSGAPGVPT 3056 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-WTKIVTVGGSVHEHCIENI 1930 F V ++ V LKW +P ++GG+ I YI+E K KG W K+ S + + + Sbjct: 3057 FTVGKTF---VDLKWDKPRNDGGAKIKGYIVE-KRAKGSDVWVKVNDYPVSDCGYTVNGL 3112 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969 E E FR+ A N G P+ + + K V + P Sbjct: 3113 PEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAP 3151 Score = 201 bits (491), Expect = 1e-49 Identities = 224/935 (23%), Positives = 388/935 (41%), Gaps = 54/935 (5%) Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDAYL 1216 GK+++ + ++DAG V + A E P ++ L I V A + Sbjct: 2024 GKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDI 2083 Query: 1217 TVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 V + T V+W K +++ K T S + L + K D +YT + + Sbjct: 2084 PVGVSGTPTPTVSWEKNGRPVDNRAKCT--SSEEDAKLHVDKAERGDTGKYTITVTNESG 2141 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKH 1333 + V V+ K E + SDV + ++ P D V +++KC+ Sbjct: 2142 SMSADVNVIVLD-KPGAPEGPLAV---SDVFADMCRLSWNPPADNGGAEVTGYVVEKCED 2197 Query: 1334 TK------PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTILDKP--SPP 1384 K P + + +A +K ++ ++++ EN G A +E + +IL K P Sbjct: 2198 GKDFWEKVPGLVNGTAH-PVKGLKEGKKYKFRVKAENKYGAGAPLETDKSILAKNPFDTP 2256 Query: 1385 GKPNILEIDSSSINIC---WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTS 1439 P LEID N C W +P+ G + I Y+VE + +W+ V N + T+ S Sbjct: 2257 DAPKDLEIDRFDKNSCDLVWKKPDFDGGADISGYIVEKRP-KGGDWVPVNNFPLADTKFS 2315 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 LK +FR AVN+ S++T+ + V K+ + P + T + ++ Sbjct: 2316 ALGLKERQVLKFRVSAVNQGSTGKPSKSTKPHTV-KDPIFAAGAPGTPNLDKITPNSAEL 2374 Query: 1500 ELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 T + ++ + KK +TA N ++ A N+ Sbjct: 2375 SWTKPTKDGGGKILGYFIEKKKGHGDWETATEVPANALHGKVNDLVEGEQYQFRIRAINE 2434 Query: 1556 HGEVE----TSCVVGIQQ--KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 G + T + Q KP + +S +DI K G ++ + + P +W Sbjct: 2435 AGPGDPSKPTQAITAEYQAEKPHLDLSGIKDITVKQ--GQKYQIRVPYKAWLKPSALWTI 2492 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + +L + + +++ ++ + +R+ S KY I +N +G S V + V P+K Sbjct: 2493 DEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPSGNHSGFVNVNVLSPPAK 2552 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 PEGP +I+ + +T+ W P DDGG +++ Y IE+ + + +W KV ++ T + Sbjct: 2553 PEGPFTASDINGDELTLSWGAPKDDGGEKISNYIIERKKKGSPKWSKVTGTAKE-PTCQV 2611 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 + L EY FRV+A+N G S LE++ I+ K D P + +S+ +T Sbjct: 2612 RNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDTPGAPGTPKCLEYTE-DSITLT 2670 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGK-KWKXX--XXXXXXXARIQKLSINTTYQFRIYARNE 1844 W P + +GG+ I Y VE K++GK W +++ L Y+FR+ ARN Sbjct: 2671 WTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNEFQVKGLQEGKEYEFRVAARNN 2730 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR-SVTLKWTEPESNGGSPITNYIIE 1903 G + I P ++F + ++ K P + P TN+ I Sbjct: 2731 AGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAKVGEPFKIVIPYNGNPIPDTNWSIG 2790 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 + + K + + + ++D + ++ +N G V ++K Sbjct: 2791 TRDLFEGDRIKFENTPNEL-KLLNKKATKEDAGRYTLTMKNEKGQD-TIALNVVVVDK-- 2846 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 PS P PLE V + +W P+ DGG+P+ Y + D W V K V Sbjct: 2847 --PSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVSNYVVEKCDTRTGRWEPVSKF-VRG 2903 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 K+ + L E H Y R+ A NE G+SEPLE EP Sbjct: 2904 AKYEVMGLDEGHEYKFRVSAENENGVSEPLEVLEP 2938 Score = 182 bits (443), Expect = 1e-43 Identities = 126/487 (25%), Positives = 212/487 (43%), Gaps = 16/487 (3%) Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQ 1441 PG P + + +++ WD+P N G + I Y+VE + + W+ V + ++ ++ Sbjct: 3052 PGVPTFT-VGKTFVDLKWDKPRNDGGAKIKGYIVEKRAKGSDVWVKVNDYPVSDCGYTVN 3110 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIE 1500 L + FR AVN+ + S TT K+ ++ +P K L P ++ Sbjct: 3111 GLPEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMI 3170 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + G P P VTWY++G + + T ++ KC N Sbjct: 3171 FSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPL 3230 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G +C IQ P D Q+ ++G+++ + G P EV KNG ++ + Sbjct: 3231 GRDSCTCNFKIQSPPKFGKDFHD--QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQN 3288 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 I + + I + + +Y +E SN G + + LKV P KP GP+ + Sbjct: 3289 GRIKIMPFDDYVSLTINDANLDDAGQYKVEVSNAGGAAELGFGLKVVGAPEKPTGPLGVS 3348 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 +I++ + ++WKPP DGG ++T Y +E+ E W+ V+ +D +Q L +N Sbjct: 3349 DITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRCKDC-NQDVQGLYDNYL 3407 Query: 1737 YMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y FRV A N G SE L +E PI+ K D P + ++ V +TW + +G Sbjct: 3408 YAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPD-APGVPEITEVGSDFVSLTWEKPKHDG 3466 Query: 1796 GSPIIDYKVEIKQEG-KKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 G I Y ++ ++ G W I KL + Y+FR++A NE G S P Sbjct: 3467 GGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYEFRVFAENEAGMSKPSM 3526 Query: 1853 SDDKITI 1859 + + I Sbjct: 3527 NSQAVKI 3533 Score = 177 bits (430), Expect = 4e-42 Identities = 112/393 (28%), Positives = 185/393 (47%), Gaps = 16/393 (4%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 DKP PG P I E+ S +++ W++P++ G I Y ++ +E T W V N+ T Sbjct: 3437 DKPDAPGVPEITEVGSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRV-NLQPCIT 3495 Query: 1439 SIQNLKT---NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 +I N+ + Y FR +A NE +S S ++ K+ P L+ + Sbjct: 3496 NIINIPKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDPKAAVIPEFSSGLRKCHAQQ 3555 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYE--NRXXXXXXXXXXXXXXXYKCI 1551 + + C G P P + W++ +++ ++ Y ++ Y C Sbjct: 3556 GKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCR 3615 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISN--EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 A N G + + I P IT+ +D+ K G+ ++ G P P + W + Sbjct: 3616 ASNHGGSRTSRANLEISSPPKITVPKRFQDVAIFEK-GESAVMKIPFTGNPKPTITWMHD 3674 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 G +++ + Y+ E+ +++ IK+ + Y I A N G+ S + +++ D+P P Sbjct: 3675 GEEVKG-RNYHSEVTERHAILTIKDANKDQDGPYRITAKNDLGSDSAVIKIQINDRPDPP 3733 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 P I ESV + WKPPL+DGG +T+Y IEK EP N WI+VA V R + + I Sbjct: 3734 RYPTC-ENIRDESVLLSWKPPLNDGGSFITQYIIEKCEPPNTNWIRVA-VSR-MCFHNIT 3790 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 L+ N EY FRV+A+N G S+ + VIKT Sbjct: 3791 SLSANKEYQFRVVAENFYGKSDPCD-PTAVIKT 3822 Score = 173 bits (422), Expect = 3e-41 Identities = 165/705 (23%), Positives = 281/705 (39%), Gaps = 44/705 (6%) Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT--SIQ 1441 PG PN+ +I +S + W +P G I+ Y +E ++ +W + + + Sbjct: 2359 PGTPNLDKITPNSAELSWTKPTKDGGGKILGYFIEKKK-GHGDWETATEVPANALHGKVN 2417 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIE 1500 +L Y+FR A+NE D S+ T+ + E + + P ++ +K+IT + + + Sbjct: 2418 DLVEGEQYQFRIRAINEAGPGDPSKPTQ--AITAEYQAEKPHLDLSGIKDITVKQGQKYQ 2475 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFN-- 1554 + + +P W D ++L + + + YK N Sbjct: 2476 IRVPYKAWLKPSALWTIDEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPS 2535 Query: 1555 -DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI--WYKNGN 1611 +H V+ KP + DI GDE ++ E I + Sbjct: 2536 GNHSGFVNVNVLSPPAKPEGPFTASDIN-----GDELTLSWGAPKDDGGEKISNYIIERK 2590 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV------YDK 1665 K + K +T K +++ L+ ++ + A N G S+ T K YD Sbjct: 2591 KKGSPKWSKVTGTAKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDT 2650 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P P P + E + +S+T+ W PP +DGG + Y +EK E W K D Sbjct: 2651 PGAPGTPKCL-EYTEDSITLTWTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNE 2709 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + ++ L E EY FRV A+N G + A S+ I + A P I Sbjct: 2710 FQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAKVGE 2769 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 P ++ + + EG + K +K + ++ + + Sbjct: 2770 PFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKEDAGRYTLTMK 2829 Query: 1843 NEIGTSLPYTSDDKITIGKTLTP-PSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNY 1900 NE G D I + + PS+P + T S TL W +P+ +GGSP++NY Sbjct: 2830 NEKG-------QDTIALNVVVVDKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVSNY 2882 Query: 1901 IIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 ++E + W + V G+ +E + + E E FR+SAEN GVS P E L Sbjct: 2883 VVEKCDTRTGRWEPVSKFVRGAKYE--VMGLDEGHEYKFRVSAENENGVSEPLEVLEPVL 2940 Query: 1960 EKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 +H T P P + + + V + V ++ P DGG + GY + +D T W Sbjct: 2941 AQHPYTAPGSP-SNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKMHND 2999 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + LK+ + L ++ Y R+ A+N GL EP + + + P Sbjct: 3000 IASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKP 3044 Score = 144 bits (349), Expect = 2e-32 Identities = 130/501 (25%), Positives = 219/501 (43%), Gaps = 43/501 (8%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 G+P P W K+GN L ++ + +I + + IRI + +R + +Y + +N G+ + Sbjct: 1488 GVPMPSGHWKKDGNPL-SEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVGSEVIP 1546 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE--KHEPDNNRWIK 1715 + ++V D P +P P+ + ++ + + W P DDGG + Y +E E D++R+ + Sbjct: 1547 IPVRVLDVPGRPGEPLDVVDVFADKCALLWDRPKDDGGSPIKHYIVEMKDSEKDSDRFEQ 1606 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXXX 1774 V + D+E + L E Y FRV A N G SE L ++ I+ K D PS Sbjct: 1607 VCTTE-DLEV-DVTGLKEGHRYQFRVRAVNEQGTSEPLLADGEIIAKDPWD-PSDPPQDT 1663 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW--KXXXXXXXXXARIQKLSI 1831 D + V I W P +GG+PI Y +E ++ +W + L+ Sbjct: 1664 NVEDYDKDYVEIGWKPPISDGGAPIEKYVIEKCEKHRPEWVPGIEVPGDKRAGTVSGLTE 1723 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK----WT 1887 N Y FR+ A N+ G S P + + LT + R ++++ + + +K +T Sbjct: 1724 NREYIFRVSAVNKAGKSEPSEATPPV-----LTKSRRVRPRIMNKDDLKPIRVKVGKDFT 1778 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSW----TKIVTVGGSVHEHCIENIKE---KDEIIFRI 1940 P G P + K + K + +++ + KE KD ++ + Sbjct: 1779 IPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSRKDTAMYNV 1838 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 + N G S + + V L PS P P+++ + + WG PE GG+P+ G Sbjct: 1839 TVTNKHG-SDTADVEVVVLGP----PSMPKGPIKVSNITAESATLEWGEPEDLGGSPIDG 1893 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES----- 2055 Y + D K W V + V K + L E Y R+ A ++ G SEPLE+ Sbjct: 1894 YKVEKMDTKKGQWEPV-REGVKGTKVTVPKLKEGQEYKFRVAAMSQNGNSEPLETKPIIA 1952 Query: 2056 ----DEPFKVIPGEGSHADEE 2072 DEPF PG+ D + Sbjct: 1953 KKPYDEPFP--PGQPKCVDRD 1971 Score = 140 bits (340), Expect = 3e-31 Identities = 119/444 (26%), Positives = 198/444 (44%), Gaps = 51/444 (11%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD---DDN 564 +AP F +K K +G + F+C +E P+P I WF+ T + S +M + +N Sbjct: 7 IAPRFTQKPVLKQEDNGKLLVFQCTLEAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGGNN 66 Query: 565 VATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 ++ I+ V DAGT+ VAKN G S++ L AP G + Sbjct: 67 YNVMMDIKGVTQADAGTYKVVAKNKLGEVSASINLNFSAP----GQKQQ----------- 111 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 +GI P F++KP + D G + I LEC+L A P P I+W ++I I + Sbjct: 112 ------DGIAPNFTQKPSTRQADNGKETICLECQLTADPVPQISWFRDDQQIKDGGRIKI 165 Query: 683 AIE-SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP- 740 + + Y VL+I V G Y V A N GE++ I L + +K PQ P Sbjct: 166 QTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNALGESNATIRLNFDSDDKGKPQGTRPS 225 Query: 741 --LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALPTKSDGDTHSITIL 792 K I + G +I +V +P+PTITW K + + K + T D + + ++++ Sbjct: 226 FTTKPAIKQVGGKIIFDCKVTADPKPTITWMKGTQALTDGGRYKMIQT-GDKNNYDVSMV 284 Query: 793 KPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENA---EPPLFINRFQEITVKEKG 848 K KD+ G Y A+NS G + + + E + A + P F+ + + +EK Sbjct: 285 IDKPGKDDGGEYKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQFLAK--PVVKQEKT 342 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE----TITQNFDGENIELVITNV--DSEIDSG 902 + + + P P+I W++ + +T + + N+ D G Sbjct: 343 NLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATLNIKDPKPTDGG 402 Query: 903 DYKCVASNSAGKSSHGARVTIDVE 926 +KC ASN G+S+ A +T++ + Sbjct: 403 SFKCTASNDFGESN--ANITLNFQ 424 Score = 138 bits (333), Expect = 2e-30 Identities = 178/750 (23%), Positives = 299/750 (39%), Gaps = 54/750 (7%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L+ +K T++D YT + + K T L V VV+ P K E ++ DVT Sbjct: 2811 LLNKKATKEDAGRYTLTMKNEKGQDTIALNVVVVDKPSK-----PEGPLEC-IDVTPDSC 2864 Query: 1311 YQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIKKVE--NTDAGI-YKLRL--E 1363 + +P D+ V++ +++KC + S + K E D G YK R+ E Sbjct: 2865 TLTWNKPKDDGGSPVSNYVVEKCDTRTGRWEPVSKFVRGAKYEVMGLDEGHEYKFRVSAE 2924 Query: 1364 NNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 N G ++ +E+ +L + P P ++L++D S+ + ++ P + G I Y V Sbjct: 2925 NENGVSEPLEVLEPVLAQHPYTAPGSPSNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCV 2984 Query: 1418 EYQEIDTTEWISVKNITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI- 1474 EY++ + W +I ++ LK + Y FR A N + + S+ T+ + Sbjct: 2985 EYKDPTSGRWKMHNDIASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKP 3044 Query: 1475 KETKIQSP-----TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 K T +P TV K ++ + + I G + + + G + Y Sbjct: 3045 KYTLSGAPGVPTFTVGKTFVDLKWDKPRNDGGAKIKGYIVEKRAK----GSDVWVKVNDY 3100 Query: 1530 E-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ--KPVITISNEDIKQKHK- 1585 + ++ A N GE E S G+ + + V+ + E IK+ H Sbjct: 3101 PVSDCGYTVNGLPEGGEFEFRVRAVNQAGEGEPSGTTGLIKIKEKVVGTAPEFIKKLHPT 3160 Query: 1586 ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 +G E + + + G P P+V WYKNG + + +T + +R EL + Sbjct: 3161 EMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEG 3220 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 + + SN G S K+ P + + E I K P G K Sbjct: 3221 EIKCDISNPLGRDSCTCNFKIQSPPKFGKDFHDQQVELGEQFKI--KIPFSGTGPFEVKV 3278 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761 E N IK+ D D + I N + ++V N G +E +V Sbjct: 3279 RKNGREVVQNGRIKIMPFD-DYVSLTINDANLDDAGQYKVEVSNAGGAAELGFGLKVV-- 3335 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821 P I + + W P + +GGS I Y VE ++ GK + Sbjct: 3336 ---GAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRC 3392 Query: 1822 XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 +Q L N Y FR+ A NE G S P T++ I P P ++E S Sbjct: 3393 KDCNQDVQGLYDNYLYAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPDAPGVPEITEVGS 3452 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 V+L W +P+ +GG I Y I+ + +W+++ + I + E FR Sbjct: 3453 DFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYEFR 3512 Query: 1940 ISAENTVGVSLPT-ESQSVRLE--KHATVP 1966 + AEN G+S P+ SQ+V+++ K A +P Sbjct: 3513 VFAENEAGMSKPSMNSQAVKIKDPKAAVIP 3542 Score = 119 bits (287), Expect = 8e-25 Identities = 108/443 (24%), Positives = 180/443 (40%), Gaps = 31/443 (6%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD---- 561 + AP F+ K P + + + C +E P+P I WF+ T +K + + Sbjct: 325 EGKAPQFLAK--PVVKQEKTNLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPG 382 Query: 562 --DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE---MTVXX 615 D ATL I++ P D G+F C A N G +++ L + A D SE Sbjct: 383 KADSYTATLNIKDPKPTDGGSFKCTASNDFGESNANITLNFQGAEQKDKPSEDQEKPAAP 442 Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675 G PTF+KKP + EG ++++ C+ A P+P +W G + Sbjct: 443 KPAEKKNKPAPAKPAGTAPTFTKKPVIK--QEGKNLIVHCKCKANPKPTFSWYKSGLPLK 500 Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--E 733 I ++ Y + L + NV K Y VVA N GE + I + + K E Sbjct: 501 ETFRIKTRVDGKGDDYDTFLDLINVTKNDAAEYKVVAKNAHGEGNATITVNMDEPPKAAE 560 Query: 734 PPQVIEPLKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTH 787 PP + L + + + G+ + ++ +V +PT W NKP+K L D D + Sbjct: 561 PPPQFQGLPQVTLEEGGKRLCITQKVKCKTKPTAMWYFLNKPIKHGGKYFLEISQDRDCY 620 Query: 788 SIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-----EPTEENAEPPLFINRFQ 840 ++ +L PK++ D G Y + G E SA + ++ +P PP + Sbjct: 621 NVVCEVLNPKEL-DSGEYKFSIKTPGGEGEGSARVDLKALMAPKPKVPKGSPPSSTQKLA 679 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 V + L+A+V N + ++ + + S+ F L I V + D Sbjct: 680 PTEVLDGDACDLIAKVAGNEPIEVVCSKDGDKLKHSKDCQITFKDNVCRLYIPEVYPD-D 738 Query: 901 SGDYKCVASNSAGKSSHGARVTI 923 G Y+ N GK+ A + + Sbjct: 739 GGKYQIDLENEFGKAMTSATLVV 761 Score = 119 bits (287), Expect = 8e-25 Identities = 96/435 (22%), Positives = 176/435 (40%), Gaps = 17/435 (3%) Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTI 1685 T+ ++K L+ ++ + A N AG T + + P P + + + R+ + Sbjct: 2707 TNEFQVKGLQEGKEYEFRVAARNNAGVGDWAQTSQAIKARAAPVAPKVDKSFTPRDVIAK 2766 Query: 1686 EWKP-----PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 +P P + + T ++I + IK + +++ + E+ + Sbjct: 2767 VGEPFKIVIPYNGNPIPDTNWSIGTRDLFEGDRIKFENTPNELKLLNKKATKEDAG-RYT 2825 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 + +N G + + +V+ D PS + +S +TW + +GGSP+ Sbjct: 2826 LTMKNEKG-QDTIALNVVVV----DKPSKPEGPLECIDVTPDSCTLTWNKPKDDGGSPVS 2880 Query: 1801 DYKVE-IKQEGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 +Y VE +W+ + L Y+FR+ A NE G S P + + Sbjct: 2881 NYVVEKCDTRTGRWEPVSKFVRGAKYEVMGLDEGHEYKFRVSAENENGVSEPLEVLEPVL 2940 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 T P P N V + SVTL + P +GG I Y +E+K W + Sbjct: 2941 AQHPYTAPGSPSNVHVLDVDEDSVTLAFNAPTHDGGKKIQGYCVEYKDPTSGRWKMHNDI 3000 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977 ++ ++ +K+ + FR+ A+N G+ P++ + +R + T+ P P Sbjct: 3001 ASPDLKYTVDGLKKDKDYEFRVRAKNIAGLGEPSKPTDVIRTKPKYTLSGAPGVP--TFT 3058 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 VG V W P DGGA + GY + R +W++V V+ + + L E + Sbjct: 3059 VGKTFVDLKWDKPRNDGGAKIKGYIVEKRAKGSDVWVKVNDYPVSDCGYTVNGLPEGGEF 3118 Query: 2038 MIRIYARNEIGLSEP 2052 R+ A N+ G EP Sbjct: 3119 EFRVRAVNQAGEGEP 3133 Score = 118 bits (284), Expect = 2e-24 Identities = 108/442 (24%), Positives = 174/442 (39%), Gaps = 32/442 (7%) Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLK---VYDK--PSKPEGPVIMREISRESVTIEWKP 1689 LK K+ + A N T + K V D + G + +I+ S + W Sbjct: 2319 LKERQVLKFRVSAVNQGSTGKPSKSTKPHTVKDPIFAAGAPGTPNLDKITPNSAELSWTK 2378 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 P DGG ++ Y IEK + + W +V + + L E +Y FR+ A N G Sbjct: 2379 PTKDGGGKILGYFIEKKKGHGD-WETATEVPANALHGKVNDLVEGEQYQFRIRAINEAGP 2437 Query: 1750 SEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 + + ++ I + + P + Y P YK +K Sbjct: 2438 GDPSKPTQAITAEYQAEKPHLDLSGIKDITVKQGQKYQIRVP-----------YKAWLKP 2486 Query: 1809 EGKKWKXXXXXXXXXARIQK-------LSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 W ARI + N Q + +I + P + Sbjct: 2487 SAL-WTIDEEELPSVARIHTKVEDEAVMLTNDKSQRADSGKYKITLTNPSGNHSGFVNVN 2545 Query: 1862 TLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 L+PP++P F S+ +TL W P+ +GG I+NYIIE K W+K+ G Sbjct: 2546 VLSPPAKPEGPFTASDINGDELTLSWGAPKDDGGEKISNYIIERKKKGSPKWSKVT--GT 2603 Query: 1921 SVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMV 1978 + C + N++ E FR+ AEN G+S P E+ L K P P P + Sbjct: 2604 AKEPTCQVRNLEPGTEYEFRVMAENAQGISAPLETDKAILAKLPYDTPGAPGTPKCLEYT 2663 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 +I +T W P+ DGG + GY + ++ K W + D+ T +F ++ L E Y Sbjct: 2664 EDSITLT-WTPPKNDGGNIIKGYVVEKKEKGKPDWTKANISDILTNEFQVKGLQEGKEYE 2722 Query: 2039 IRIYARNEIGLSEPLESDEPFK 2060 R+ ARN G+ + ++ + K Sbjct: 2723 FRVAARNNAGVGDWAQTSQAIK 2744 Score = 117 bits (282), Expect = 3e-24 Identities = 174/718 (24%), Positives = 302/718 (42%), Gaps = 114/718 (15%) Query: 476 DENNYTQYLQKKLNEKIDKLPV-FEKPTSEEQS-MAPIFVEKLRPKHTPDGS-TVQFECQ 532 D Y + KL E + + F P ++Q +AP F +K + +G T+ ECQ Sbjct: 80 DAGTYKVVAKNKLGEVSASINLNFSAPGQKQQDGIAPNFTQKPSTRQADNGKETICLECQ 139 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYD----DDNVATLVIREVFPEDAGTFTCVAKNA 588 + P PQI+WFR IK ++ D ++ L I V +DAG + AKNA Sbjct: 140 LTADPVPQISWFRDDQQIKDGGRIKIQTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNA 199 Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 G +++T L ++ D G +G P+F+ KP + V G Sbjct: 200 LGESNATIRLNFDS--DDKGKP-------------------QGTRPSFTTKPAIKQV--G 236 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYCSVLKITNVKKFQEGT 707 I+ +C++ A P+P I W+ KG + + D I++ D + Y + I K G Sbjct: 237 GKIIFDCKVTADPKPTITWM-KGTQALTDGGRYKMIQTGDKNNYDVSMVIDKPGKDDGGE 295 Query: 708 YTVVAVNREGEASLPIVLKIKT-GEKEPPQVIEP---LKSMIVRQGESVILSAQVVGNPR 763 Y +A N G+++ I L + G K+ P+ P K ++ ++ ++I++ + P+ Sbjct: 296 YKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQFLAKPVVKQEKTNLIMTCNLEAKPQ 355 Query: 764 PTITWCKNNK--------PVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIA 814 P I W + +K P+ D+++ T+ +K K D G + A N G Sbjct: 356 PNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATLNIKDPKPTDGGSFKCTASNDFG-- 413 Query: 815 ETSAVITV--------EEPTEENAEP--PLFINR----------------FQEITVKEKG 848 E++A IT+ ++P+E+ +P P + ++ +K++G Sbjct: 414 ESNANITLNFQGAEQKDKPSEDQEKPAAPKPAEKKNKPAPAKPAGTAPTFTKKPVIKQEG 473 Query: 849 TIKLV-ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE----LVITNVDSEIDSGD 903 +V + NP P+ +WY++ + + I DG+ + L + NV ++ D+ + Sbjct: 474 KNLIVHCKCKANPKPTFSWYKSGLPLKETFRIKTRVDGKGDDYDTFLDLINV-TKNDAAE 532 Query: 904 YKCVASNSAGKSSHGARVTID-----VEKVTFVKHLQKSYETEEGK----TVILECQTSH 954 YK VA N+ G+ + V +D E + L + E GK T ++C+T Sbjct: 533 YKVVAKNAHGEGNATITVNMDEPPKAAEPPPQFQGLPQVTLEEGGKRLCITQKVKCKTKP 592 Query: 955 TVSTKWYHNKKEI--SGMDHREIIQEG--RXXXXXXXXXXXXDVGVIKCIVK----DQET 1006 T WY K I G EI Q+ D G K +K + E Sbjct: 593 T--AMWYFLNKPIKHGGKYFLEISQDRDCYNVVCEVLNPKELDSGEYKFSIKTPGGEGEG 650 Query: 1007 STML-----------VVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054 S + V K + P +KL EV + D L ++ +E +VV +DG+ Sbjct: 651 SARVDLKALMAPKPKVPKGSPPSSTQKLAPTEVLDGDACDLIAKVAGNEPIEVVCSKDGD 710 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEI 1109 +K K+ + ++ +LYI D G+Y L +E + T+ VV P++ Sbjct: 711 KLKHSKD-CQITFKDNVCRLYIPEVYPDDGGKYQIDLENEFGKAMTSATLVVSENPDM 767 Score = 111 bits (268), Expect = 2e-22 Identities = 85/316 (26%), Positives = 155/316 (49%), Gaps = 23/316 (7%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDM 688 + I P F++KP + D G ++ +C L A P+PDI W + + I + +E + Sbjct: 5 DDIAPRFTQKPVLKQEDNGKLLVFQCTLEAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGG 64 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKE-----PPQVIEPLK 742 + Y ++ I V + GTY VVA N+ GE S I L G+K+ P +P Sbjct: 65 NNYNVMMDIKGVTQADAGTYKVVAKNKLGEVSASINLNFSAPGQKQQDGIAPNFTQKPST 124 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKV 797 E++ L Q+ +P P I+W ++++ +K + T G+ + +L+ V Sbjct: 125 RQADNGKETICLECQLTADPVPQISWFRDDQQIKDGGRIKIQTDPKGNNNYFIVLEINGV 184 Query: 798 --KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKE-KGTIKLV 853 +D G Y + A+N+ G E++A I + +++ +P F + +K+ G I Sbjct: 185 NAQDAGNYRVTAKNALG--ESNATIRLNFDSDDKGKPQGTRPSFTTKPAIKQVGGKIIFD 242 Query: 854 ARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIEL-VITNVDSEIDSGDYKCVASN 910 +VT +P P+ITW + + ++ + Q D N ++ ++ + + D G+YKC+A N Sbjct: 243 CKVTADPKPTITWMKGTQALTDGGRYKMIQTGDKNNYDVSMVIDKPGKDDGGEYKCLAKN 302 Query: 911 SAGKSSHGARVTIDVE 926 S G S+ A +T++ E Sbjct: 303 SLGDST--ATITLNFE 316 Score = 111 bits (267), Expect = 2e-22 Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 7/260 (2%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283 D+ W+K I + KF + ++ K+ LI+ +DQ EY+C + T++ +E+ Sbjct: 3572 DIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEI 3631 Query: 1284 VEFPPKIVDYEREYRI---KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 PPKI +R + ++G + + + P+P W+ + + +K ++ + Sbjct: 3632 SS-PPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEEVKG-RNYHSEVTE 3689 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 + A LTIK G Y++ +N+ G + + I D+P PP P I S+ + Sbjct: 3690 RHAILTIKDANKDQDGPYRITAKNDLGSDSAVIKIQINDRPDPPRYPTCENIRDESVLLS 3749 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 W P N G S I Y++E E T WI V +I +L N Y+FR A N Sbjct: 3750 WKPPLNDGGSFITQYIIEKCEPPNTNWIRVAVSRMCFHNITSLSANKEYQFRVVAENFYG 3809 Query: 1461 ISDASETTEYYKVIKETKIQ 1480 SD + T K + I+ Sbjct: 3810 KSDPCDPTAVIKTDESDAIK 3829 Score = 96.3 bits (229), Expect = 8e-18 Identities = 61/203 (30%), Positives = 100/203 (49%), Gaps = 4/203 (1%) Query: 1861 KTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919 K + P +P + VS+ T + L+W P+++GGS IT+Y++E + V W + + Sbjct: 3333 KVVGAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHYVVERQEVGKPYWVTVSSRC 3392 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMV 1978 ++ ++ + + FR+SA N G S P +++ + K P P P EI V Sbjct: 3393 KDCNQD-VQGLYDNYLYAFRVSAVNEFGQSEPLTAETPIIAKMPFDKPDAPGVP-EITEV 3450 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 GS+ V +W P+ DGG + GY I R+ W V T NI L E+ Y Sbjct: 3451 GSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTDNWSRVNLQPCITNIINIPKLIEDKRYE 3510 Query: 2039 IRIYARNEIGLSEPLESDEPFKV 2061 R++A NE G+S+P + + K+ Sbjct: 3511 FRVFAENEAGMSKPSMNSQAVKI 3533 Score = 90.2 bits (214), Expect = 5e-16 Identities = 110/428 (25%), Positives = 186/428 (43%), Gaps = 36/428 (8%) Query: 1653 TSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 T+ + K+ +DKP P P I E+ + V++ W+ P DGG + Y I+K E + Sbjct: 3425 TAETPIIAKMPFDKPDAPGVPEIT-EVGSDFVSLTWEKPKHDGGGRIKGYWIDKREHGTD 3483 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT--ALDVPS 1768 W +V I KL E+ Y FRV A+N G S+ ++ S+ + IK A +P Sbjct: 3484 NWSRVNLQPCITNIINIPKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDPKAAVIPE 3543 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXAR 1825 +S F E +G SP I + ++ K++ Sbjct: 3544 FSSGLRKCHAQQGKSAK---FECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLI 3600 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + + ++ A N G S ++ +I+ +T P + ++ + E S +K Sbjct: 3601 VHDVFGEDQDEYSCRASNH-GGSRTSRANLEISSPPKITVPKRFQDVAIFEK-GESAVMK 3658 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE--KDEI-IFRISA 1942 P + P ++ + + VKG+++ VT H I IK+ KD+ +RI+A Sbjct: 3659 I--PFTGNPKPTITWMHDGEEVKGRNYHSEVT-----ERHAILTIKDANKDQDGPYRITA 3711 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 +N +G ++S ++++ + P PP P + V+ SW P DGG+ + Y Sbjct: 3712 KNDLG----SDSAVIKIQINDR-PDPPRYPT-CENIRDESVLLSWKPPLNDGGSFITQYI 3765 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKF-NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 I + T W+ +V V+ + F NI LS N Y R+ A N G S+P +P V Sbjct: 3766 IEKCEPPNTNWI---RVAVSRMCFHNITSLSANKEYQFRVVAENFYGKSDPC---DPTAV 3819 Query: 2062 IPGEGSHA 2069 I + S A Sbjct: 3820 IKTDESDA 3827 Score = 86.6 bits (205), Expect = 7e-15 Identities = 68/289 (23%), Positives = 121/289 (41%), Gaps = 8/289 (2%) Query: 1183 SKCTAILTVEEPSIN----FTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIE 1237 S T ++ ++E + F +L + P + +V++ + + DVTWYK + Sbjct: 3134 SGTTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMG 3193 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE 1296 T + L + TL + +D+ E C + + ++ PPK + Sbjct: 3194 STSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPLGRDSCTCNFKIQSPPKFGKDFHD 3253 Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 +++ G + + + + N + + + K SLTI DAG Sbjct: 3254 QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQNGRIKIMPFDDYVSLTINDANLDDAG 3313 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYY 1415 YK+ + N G A++ + ++ P P P + +I S+ + W P+ G S I +Y Sbjct: 3314 QYKVEVSNAGGAAELGFGLKVVGAPEKPTGPLGVSDITKSTCRLQWKPPKTDGGSKITHY 3373 Query: 1416 VVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 VVE QE+ W++V + K +Q L N Y FR AVNE S+ Sbjct: 3374 VVERQEVGKPYWVTVSSRCKDCNQDVQGLYDNYLYAFRVSAVNEFGQSE 3422 Score = 79.0 bits (186), Expect = 1e-12 Identities = 89/430 (20%), Positives = 165/430 (38%), Gaps = 41/430 (9%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 + + AP F+ K R +G + +F+C++ G P +TW +++ S + Y Sbjct: 4196 DRKEAAPRFIRKPRNILAAEGQSTKFDCKIIGASPPIVTWSYDNSVLSQSVKYMQKY-RG 4254 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-------PLSDHGSEMTVXXX 616 N L I + D G +T +A+N+ G L VE P S + M Sbjct: 4255 NEYELKISRLKMADKGLYTVIAENSFGKREEHATLKVEVNPELQRMPSSRDTTPMRRSRR 4314 Query: 617 XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP 676 + E +F +P+ + GS+ L + + P P + W +++ Sbjct: 4315 PSMSPAPEVKPVEEAPKISFGLRPR--LIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAK 4372 Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEP 734 D + + + + +K+ + K GTYT A+N E E S +V++ + + + Sbjct: 4373 DPHYMCSYSGGV----ATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDK 4428 Query: 735 PQVIEPLK-SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 + + K S R +S A + T T + + T + H Sbjct: 4429 SDIFKSHKQSRTARTTKSGFSFADSSSSYNETSTSSSSTR------TSNRSSRH------ 4476 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 V E+S + +S EP + E P F + +++ E +KL Sbjct: 4477 --------VEKSSYEDSYSSSRSSPRDKKREP---SVEAPEFTTQLSPLSLNEGDRLKLT 4525 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 V P P + W+ N +++ + I + + L I + + D G+Y C A N G Sbjct: 4526 CTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIID-DDGNYVCKAKNPGG 4584 Query: 914 KSSHGARVTI 923 ++S V + Sbjct: 4585 QASSRTSVQV 4594 Score = 76.6 bits (180), Expect = 7e-12 Identities = 59/207 (28%), Positives = 92/207 (44%), Gaps = 18/207 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYC 692 P FS + + +G EC + P PDI W FKG EI + E D Sbjct: 3542 PEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRW-FKGTREIYSSPKFEIYNEGDKQ--- 3597 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM---IVRQG 749 VL + +V + Y+ A N G + L+I + PP++ P + I +G Sbjct: 3598 -VLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEISS----PPKITVPKRFQDVAIFEKG 3652 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVKDEGVYTLKAE 808 ES ++ GNP+PTITW + + VK S+ + H+I +K +G Y + A+ Sbjct: 3653 ESAVMKIPFTGNPKPTITWMHDGEEVKGRNYHSEVTERHAILTIKDANKDQDGPYRITAK 3712 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLF 835 N G SAVI ++ + +PP + Sbjct: 3713 NDLG--SDSAVIKIQ--INDRPDPPRY 3735 Score = 71.7 bits (168), Expect = 2e-10 Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 1/97 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 ++ P F LR H G + +FEC+V G P P I WF+ T I S F++Y + D Sbjct: 3539 AVIPEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDK-Q 3597 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L++ +VF ED ++C A N G +S L + +P Sbjct: 3598 VLIVHDVFGEDQDEYSCRASNHGGSRTSRANLEISSP 3634 Score = 68.9 bits (161), Expect = 1e-09 Identities = 80/347 (23%), Positives = 139/347 (40%), Gaps = 31/347 (8%) Query: 759 VGNPRPTITWCKNNKPVKALPTKSD---GDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 V +PR + W KN +P++ K + + I +K + DE YT G A+ Sbjct: 1213 VSDPRARVKWFKNGQPIEYQSGKMEIQRRENRCILRIKDCQPDDEAEYTCTC----GDAK 1268 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 T+ V +P + F+ ++ E+ V +P + W RN++ ++ Sbjct: 1269 TTCQFKVTDPEWD------FMKLLDDVEGIERDRATFECDV-NDPEAEVKWSRNDKELTS 1321 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 DG LV+ N S+ D G Y C + +++ V DV+ F K L+ Sbjct: 1322 GGKYEIQVDGFKRRLVVKNCHSK-DDGPYTCKVLDK--ETTANLFVEPDVK---FFKKLE 1375 Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXX 992 E E+G T++LEC+ S H KW + + I+ D R E+ ++G Sbjct: 1376 NKREREKG-TLVLECKASNPHNQPVKWLKDGEPINKDDPRLEVTRKGELYKIVIKNLTRE 1434 Query: 993 DVGVIKCIVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVE---INSETADV 1047 D G C V ++ + ++V E P+ K E+ K ++E+ I Sbjct: 1435 DAGQYACQVGERSSKWEVIVDELPKPPQINAKDIPEEIIVKKGEVIEIGIPFIGVPMPSG 1494 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 W++DG + D + + I + D G+Y L +E Sbjct: 1495 HWKKDGNPLSEADT--DIRMTDTLASIRIPDAQRGDTGQYELTLTNE 1539 Score = 65.3 bits (152), Expect = 2e-08 Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 12/258 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P P++ W+K ++ + ++ I + V+ + ++ +Y+ ASN G+ + Sbjct: 3565 VSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGEDQDEYSCRASNHGGSRT 3624 Query: 1656 VEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 L++ P K P ++++ + + K P + + E + Sbjct: 3625 SRANLEI-SSPPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEEVKGRNY 3683 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 ++V I+ N++ + +R+ A+N +G S+ VIK ++ Sbjct: 3684 H--SEVTERHAILTIKDANKDQDGPYRITAKNDLG------SDSAVIKIQINDRPDPPRY 3735 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSIN 1832 I +ESV ++W P +GGS I Y +E + W I LS N Sbjct: 3736 PTCENIRDESVLLSWKPPLNDGGSFITQYIIEKCEPPNTNWIRVAVSRMCFHNITSLSAN 3795 Query: 1833 TTYQFRIYARNEIGTSLP 1850 YQFR+ A N G S P Sbjct: 3796 KEYQFRVVAENFYGKSDP 3813 Score = 62.1 bits (144), Expect = 2e-07 Identities = 58/248 (23%), Positives = 102/248 (41%), Gaps = 19/248 (7%) Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 +V+ VE PKI R I+ GS+ LL Q+ P P W ++K + K H S Sbjct: 4322 EVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYS 4381 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 A++ ++ + D G Y R N G + V + D+ K +I + S Sbjct: 4382 GGVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDKSDIFKSHKQS--- 4438 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 T +T + D++ S N T T +S SS R + Sbjct: 4439 ------RTARTT----KSGFSFADSS---SSYNETSTSSSSTRTSNRSS---RHVEKSSY 4482 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 + S +S + +E +++P L ++ + ++LTC G P+P+V W+ +G Sbjct: 4483 EDSYSSSRSSPRDKKREPSVEAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNG 4542 Query: 1520 KKLKTAKA 1527 + +++ A Sbjct: 4543 QLMQSDDA 4550 Score = 60.9 bits (141), Expect = 4e-07 Identities = 52/227 (22%), Positives = 99/227 (43%), Gaps = 11/227 (4%) Query: 794 PKKVKDEGV-YTLKAENSEGIAE---TSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 PK ++D+ + + AEN G+++ S + +++P + A P F + ++ ++ + Sbjct: 3501 PKLIEDKRYEFRVFAENEAGMSKPSMNSQAVKIKDP--KAAVIPEFSSGLRKCHAQQGKS 3558 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 K V+ P P I W++ I S +G+ L++ +V E D +Y C AS Sbjct: 3559 AKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIVHDVFGE-DQDEYSCRAS 3617 Query: 910 NSAGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKE 966 N G + A + I K+T K Q E+G++ +++ T + T W H+ +E Sbjct: 3618 NHGGSRTSRANLEISSPPKITVPKRFQDVAIFEKGESAVMKIPFTGNPKPTITWMHDGEE 3677 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 + G ++ + E D G + K+ S V+K Sbjct: 3678 VKGRNYHSEVTERHAILTIKDANKDQD-GPYRITAKNDLGSDSAVIK 3723 Score = 60.1 bits (139), Expect = 7e-07 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 13/189 (6%) Query: 1006 TSTMLVVKE----TIPEFIRKLQDFEVKEKD-VAILEVEINSETA-DVVWERDGEIIKPK 1059 T+ ++ +KE T PEFI+KL E+ I V+++ + DV W ++G + Sbjct: 3136 TTGLIKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNG-VPMGS 3194 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQN 1115 ++ + + L +DEGE C + + +SCT + + PP+ + Sbjct: 3195 TSRTRLTQNDDVFTLRFTELYANDEGEIKCDISNPLGRDSCTCNFKI-QSPPKFGKDFHD 3253 Query: 1116 QKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 Q+V G + +I + G V+ K+G E+ + I++ L I D +LDDAG Sbjct: 3254 QQVELGEQFKIKIPFSGTGPFEVKVRKNGREVVQNGRIKIMPFDDYVSLTINDANLDDAG 3313 Query: 1175 EYSCEVGNS 1183 +Y EV N+ Sbjct: 3314 QYKVEVSNA 3322 Score = 54.4 bits (125), Expect = 3e-05 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 2/96 (2%) Query: 509 APIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 AP F++KL P P G + F QV G P P +TW++ + + ++ +DD V T Sbjct: 3150 APEFIKKLHPTEMGPLGGEMIFSVQVHGKPMPDVTWYKNGVPMGSTSRTRLTQNDD-VFT 3208 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L E++ D G C N G S T +++P Sbjct: 3209 LRFTELYANDEGEIKCDISNPLGRDSCTCNFKIQSP 3244 Score = 54.0 bits (124), Expect = 4e-05 Identities = 43/135 (31%), Positives = 68/135 (50%), Gaps = 11/135 (8%) Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQV-IEPL---KSMIVRQGESVI 753 V K +E Y VVA+N G + + K+ EKE P+V ++ L + V+ GE + Sbjct: 2023 VGKEKEYEYRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLD 2082 Query: 754 LSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + V G P PT++W KN +PV +A T S+ D + + K ++ D G YT+ N Sbjct: 2083 IPVGVSGTPTPTVSWEKNGRPVDNRAKCTSSEEDA-KLHVDKAER-GDTGKYTITVTNES 2140 Query: 812 GIAETSA-VITVEEP 825 G VI +++P Sbjct: 2141 GSMSADVNVIVLDKP 2155 Score = 53.2 bits (122), Expect = 8e-05 Identities = 86/425 (20%), Positives = 153/425 (36%), Gaps = 48/425 (11%) Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-----LTIKKVENTDAGIYKLRLENNC 1366 +A P+P+ +W + + + K ++ + + IK V DAG YK+ +N Sbjct: 33 EAAPKPDIKWFQGTTPLSQSDRIKMRVEPAGGNNYNVMMDIKGVTQADAGTYKVVAKNKL 92 Query: 1367 GH--ADVEMNVTILDKPSPPG-------KPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 G A + +N + + G KP+ + D+ IC + I + Sbjct: 93 GEVSASINLNFSAPGQKQQDGIAPNFTQKPSTRQADNGKETICLECQLTADPVPQISWFR 152 Query: 1418 EYQEIDTTEWISVKNITKTQTS------IQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 + Q+I I ++ K + I + + +R A N + S+A+ + Sbjct: 153 DDQQIKDGGRIKIQTDPKGNNNYFIVLEINGVNAQDAGNYRVTAKNALGESNATIRLNFD 212 Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKTA 1525 K K Q K + I C P+P +TW + DG + K Sbjct: 213 SDDK-GKPQGTRPSFTTKPAIKQVGGKIIFDCKVTADPKPTITWMKGTQALTDGGRYKMI 271 Query: 1526 KATYENRXXXXXXXX--XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ- 1582 + +N YKC+A N G+ + + + K Q Sbjct: 272 QTGDKNNYDVSMVIDKPGKDDGGEYKCLAKNSLGDSTATITLNFEAKGAKKAPEGKAPQF 331 Query: 1583 --KHKVGDE---WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-------TTKEKTSVI 1630 K V E ++T +E P P + W++ +L+ Y+I T+ + Sbjct: 332 LAKPVVKQEKTNLIMTCNLEAKPQPNIKWFQGTTELKMGGRYDIKLTPSPGKADSYTATL 391 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-----DKPSK-PEGPVIMREISRESVT 1684 IK+ K + + ASN G S+ +TL DKPS+ E P + +++ Sbjct: 392 NIKDPKPTDGGSFKCTASNDFGESNANITLNFQGAEQKDKPSEDQEKPAAPKPAEKKNKP 451 Query: 1685 IEWKP 1689 KP Sbjct: 452 APAKP 456 Score = 50.0 bits (114), Expect = 7e-04 Identities = 77/389 (19%), Positives = 148/389 (38%), Gaps = 47/389 (12%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSIT 790 P+ I ++++ +G+S +++G P +TW +N + VK + K G+ + + Sbjct: 4202 PRFIRKPRNILAAEGQSTKFDCKIIGASPPIVTWSYDNSVLSQSVKYMQ-KYRGNEYELK 4260 Query: 791 ILKPKKVKDEGVY---------------TLKAE-NSE-----GIAETSAVITVEEPTEEN 829 I + K+ D+G+Y TLK E N E +T+ + P+ Sbjct: 4261 ISR-LKMADKGLYTVIAENSFGKREEHATLKVEVNPELQRMPSSRDTTPMRRSRRPSMSP 4319 Query: 830 A-------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 A E P + ++ KL+ V PVP +TWY++N+ ++ + Sbjct: 4320 APEVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCS 4379 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK-HLQKSYETE 941 + G + + +D+G Y C A N G+ +RV ++ F K + KS+ + Sbjct: 4380 YSG-GVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFDKSDIFKSH--K 4436 Query: 942 EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 + +T + +N+ S R R + Sbjct: 4437 QSRTARTTKSGFSFADSSSSYNETSTSSSSTR---TSNRSSRHVEKSSYEDSYSSSRSSP 4493 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK 1060 +D++ + PEF +L + E D L + + +V W +G++++ Sbjct: 4494 RDKKREPSV----EAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDD 4549 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 GH L I + + D+G Y C Sbjct: 4550 AIKISAIAGH-HTLTIDSCIIDDDGNYVC 4577 Score = 49.2 bits (112), Expect = 0.001 Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 PE + L+ +G A FE E++ K +RWFK EI S ++ +G KQ L + Sbjct: 3542 PEFSSGLRKCHAQQGKSAKFECEVSGKPSPDIRWFKGTREIYSSPKFEIYNEGDKQVLIV 3601 Query: 1166 YDCDLDDAGEYSCEVGN 1182 +D +D EYSC N Sbjct: 3602 HDVFGEDQDEYSCRASN 3618 Score = 48.4 bits (110), Expect = 0.002 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 3/128 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 GD + A + G P EV+ K+G+KL++ K+ IT K+ + I E+ KY I+ Sbjct: 686 GDACDLIAKVAGNEPIEVVCSKDGDKLKHSKDCQITFKDNVCRLYIPEVYPDDGGKYQID 745 Query: 1647 ASNTAGTSSVEVTLKVYDKP--SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 N G + TL V + P + PE ++ + V IE K P + + K + Sbjct: 746 LENEFGKAMTSATLVVSENPDMALPEVTPMLGDDPTGKV-IEQKIPEPEQVKPVEKIQPQ 804 Query: 1705 KHEPDNNR 1712 EP+ ++ Sbjct: 805 IKEPEKSK 812 Score = 48.0 bits (109), Expect = 0.003 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 ES +E V L P ++ Q+Q +++G L + D+ V+W KDG+E+Q + Sbjct: 4635 ESRISEPDVDPLAPVFLSHPQSQSLDEGTAFKASCTLDEADS-VKWSKDGTEVQDTGRFN 4693 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 T D K +I D+GEY+ NS+ ++ Sbjct: 4694 FTQDENKFTFEIPAALATDSGEYTVTAKNSRASS 4727 Score = 47.2 bits (107), Expect = 0.005 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 6/143 (4%) Query: 459 QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518 ++H T + P M + T +++ + P KP E AP LRP Sbjct: 4284 EEHATLKVEVNPELQRMPSSRDTTPMRRSRRPSMSPAPEV-KPVEE----APKISFGLRP 4338 Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 + GS + V+ P P++TW++ + + Y VAT+ ++ D Sbjct: 4339 RLIQAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSG-GVATIKVQSAKLVDT 4397 Query: 579 GTFTCVAKNAAGFASSTTELIVE 601 GT+TC A N G +++ ++VE Sbjct: 4398 GTYTCRAINELGEHETSSRVVVE 4420 Score = 44.4 bits (100), Expect = 0.035 Identities = 60/224 (26%), Positives = 93/224 (41%), Gaps = 21/224 (9%) Query: 705 EGTYTVVAVNR--EGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQ-GESVILSAQV 758 E + V AVN+ EGE S L IK EK P+ I+ L + G +I S QV Sbjct: 3117 EFEFRVRAVNQAGEGEPSGTTGL-IKIKEKVVGTAPEFIKKLHPTEMGPLGGEMIFSVQV 3175 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAET 816 G P P +TW KN P+ + + L+ ++ DEG +K + S + Sbjct: 3176 HGKPMPDVTWYKNGVPMGSTSRTRLTQNDDVFTLRFTELYANDEG--EIKCDISNPLGRD 3233 Query: 817 SAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 S + + PP F F Q++ + E+ IK+ T P E++ Sbjct: 3234 SCTCNFKIQS-----PPKFGKDFHDQQVELGEQFKIKIPFSGT-GPFEVKVRKNGREVVQ 3287 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 FD + + L I + + + D+G YK SN+ G + G Sbjct: 3288 NGRIKIMPFD-DYVSLTINDANLD-DAGQYKVEVSNAGGAAELG 3329 Score = 44.4 bits (100), Expect = 0.035 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 6/107 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSI 789 E P+ L + + +G+ + L+ V G P P + W N + ++ A+ + H++ Sbjct: 4503 EAPEFTTQLSPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTL 4562 Query: 790 TILKPKKVKDEGVYTLKAENSEGIA--ETSAVITVEEPTEENAEPPL 834 TI + D+G Y KA+N G A TS +T P + + P + Sbjct: 4563 TI-DSCIIDDDGNYVCKAKNPGGQASSRTSVQVTENRPVKSSTPPQI 4608 Score = 44.4 bits (100), Expect = 0.035 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 GD +T ++G P PEV W+ NG +++D I+ + I Y + Sbjct: 4519 GDRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIIDDDGNYVCK 4578 Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKP--PLDDGGLELTKYAI 1703 A N G +S +++V + +P K P ++ S IE L+DG + I Sbjct: 4579 AKNPGGQASSRTSVQVTENRPVKSSTPPQIKSSSPRPDFIEHPTGVSLEDGDKATLESRI 4638 Query: 1704 EKHEPD 1709 EPD Sbjct: 4639 S--EPD 4642 Score = 42.7 bits (96), Expect = 0.11 Identities = 50/242 (20%), Positives = 88/242 (36%), Gaps = 15/242 (6%) Query: 947 ILEC-QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI----V 1001 +L C Q++ WY + K+++ H G D G C + Sbjct: 4349 LLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYTCRAINEL 4408 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 + ETS+ +VV++ +F K F+ ++ + AD + Sbjct: 4409 GEHETSSRVVVEDRAHDF-DKSDIFKSHKQSRTARTTKSGFSFADSSSSYNETSTSSSST 4467 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 + H+ K +S D YS VE P E T+L +N+G Sbjct: 4468 RTSNRSSRHVEK-----SSYEDS--YSSSRSSPRDKKREPSVEAP-EFTTQLSPLSLNEG 4519 Query: 1122 NKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 ++ + + + V WF +G +Q + I+++ L I C +DD G Y C+ Sbjct: 4520 DRLKLTCTVKGQPEPEVEWFYNGQLMQSDDAIKISAIAGHHTLTIDSCIIDDDGNYVCKA 4579 Query: 1181 GN 1182 N Sbjct: 4580 KN 4581 Score = 42.3 bits (95), Expect = 0.14 Identities = 68/305 (22%), Positives = 118/305 (38%), Gaps = 21/305 (6%) Query: 1099 EVTVVELPPEIITRLQNQKVNKGN--KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156 EV VE P+I L+ + + G+ K ++ T V W+KD ++ H + Sbjct: 4322 EVKPVEEAPKISFGLRPRLIQAGSEFKLLTCVQSTPVPK-VTWYKDNKDVAKDPHYMCSY 4380 Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 G +K+ L D G Y+C E+G + ++ + VE+ + +F + F + Sbjct: 4381 SGGVATIKVQSAKLVDTGTYTCRAINELGEHETSSRVVVEDRAHDFD-KSDIFKSHKQSR 4439 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 A T + Y + S + T S+ R + + ED D Sbjct: 4440 TARTTKSGFSFADSSSSYNETST---SSSSTRTSNRSSRH-VEKSSYEDSYSSSRSSPRD 4495 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 K + VE EF ++ + G + L + P+P EW N ++++ Sbjct: 4496 KK--REPSVEAPEFTTQL----SPLSLNEGDRLKLTCTVKGQPEPEVEWFYNGQLMQSDD 4549 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILE 1391 K S + +LTI D G Y + +N G A +V + + +P P + Sbjct: 4550 AIKISAIAGHHTLTIDSCIIDDDGNYVCKAKNPGGQASSRTSVQVTENRPVKSSTPP--Q 4607 Query: 1392 IDSSS 1396 I SSS Sbjct: 4608 IKSSS 4612 Score = 41.9 bits (94), Expect = 0.19 Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 11/180 (6%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F KK + + E ++LEC+ + WL GE I D+ + + +Y V+ Sbjct: 1370 FFKKLENKREREKGTLVLECKASNPHNQPVKWLKDGEPINKDDP-RLEVTRKGELYKIVI 1428 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVI 753 K N+ + G Y R + + IV ++ +PPQ+ + + +IV++GE + Sbjct: 1429 K--NLTREDAGQYACQVGERSSKWEV-IVDELP----KPPQINAKDIPEEIIVKKGEVIE 1481 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + +G P P+ W K+ P+ T DT + + + D G Y L N G Sbjct: 1482 IGIPFIGVPMPSGHWKKDGNPLSEADTDIRMTDTLASIRIPDAQRGDTGQYELTLTNEVG 1541 Score = 41.9 bits (94), Expect = 0.19 Identities = 19/81 (23%), Positives = 35/81 (43%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G E+ + ++ P P+V WYK+ + D Y + + I+++ K + YT Sbjct: 4342 QAGSEFKLLTCVQSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYT 4401 Query: 1645 IEASNTAGTSSVEVTLKVYDK 1665 A N G + V D+ Sbjct: 4402 CRAINELGEHETSSRVVVEDR 4422 Score = 37.9 bits (84), Expect = 3.0 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 6/89 (6%) Query: 1501 LTCIFGGVPQPKVTWYRDGK---KLKTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDH 1556 LTC+ P PKVTWY+D K K +Y Y C A N+ Sbjct: 4350 LTCV-QSTPVPKVTWYKDNKDVAKDPHYMCSYSGGVATIKVQSAKLVDTGTYTCRAINEL 4408 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK 1585 GE ETS V ++ + DI + HK Sbjct: 4409 GEHETSSRVVVEDR-AHDFDKSDIFKSHK 4436 Score = 37.1 bits (82), Expect = 5.3 Identities = 28/124 (22%), Positives = 51/124 (41%), Gaps = 6/124 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRN 859 Y + A N G +E S V + E P + ++ EI VK + + V+ Sbjct: 2031 YRVVAINDAGPSEPSVASKVIQAKPEKEAPKVSLDGLFGANEIRVKAGEPLDIPVGVSGT 2090 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P+++W +N + T + E+ +L + + D+G Y +N +G S Sbjct: 2091 PTPTVSWEKNGRPVDNRAKCTSS--EEDAKLHVDKAERG-DTGKYTITVTNESGSMSADV 2147 Query: 920 RVTI 923 V + Sbjct: 2148 NVIV 2151 Score = 36.7 bits (81), Expect = 7.0 Identities = 22/77 (28%), Positives = 31/77 (40%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G PP V W + + L +Y + ++I LK + YT+ A N+ G Sbjct: 4225 IIGASPPIVTWSYDNSVLSQSVKYMQKYRGNEYELKISRLKMADKGLYTVIAENSFGKRE 4284 Query: 1656 VEVTLKVYDKPSKPEGP 1672 TLKV P P Sbjct: 4285 EHATLKVEVNPELQRMP 4301 Score = 36.3 bits (80), Expect = 9.2 Identities = 34/145 (23%), Positives = 64/145 (44%), Gaps = 20/145 (13%) Query: 697 ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQG 749 ++ + + +E + V AVN+ G EA+ P++ K + + P+++ + LK + V+ G Sbjct: 1718 VSGLTENREYIFRVSAVNKAGKSEPSEATPPVLTKSR---RVRPRIMNKDDLKPIRVKVG 1774 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS------DGDTH---SITILKPKKVKDE 800 + + + +G P P I W K K P + D T ++T +P + KD Sbjct: 1775 KDFTIPVEYIGEPTPKIEWKKKGLDKKEEPLEPSDHISIDNKTEKKSTLTCKEPSR-KDT 1833 Query: 801 GVYTLKAENSEGIAETSAVITVEEP 825 +Y + N G + V P Sbjct: 1834 AMYNVTVTNKHGSDTADVEVVVLGP 1858 >UniRef50_A5X6X5 Cluster: Titin a; n=10; Euteleostomi|Rep: Titin a - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 32757 Score = 312 bits (765), Expect = 9e-83 Identities = 324/1447 (22%), Positives = 577/1447 (39%), Gaps = 89/1447 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +LEG P F+ K + E +++L C V+ + W G EI P +N+ + + Sbjct: 11713 VLEG-EPYFTTKLQDYTAVEKDEVVLMCE-VSKSSAQVKWFKDGNEITPSKNVLIKADGK 11770 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 +L + +K G Y + + A L I E+ +++ PL S+ V Sbjct: 11771 KR----ILTVKKAEKGNIGEYVCDCGSDKTAAKLNI-------EERDIKIVRPLYSVEVT 11819 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--SITILKPKKVKDEG---- 801 + E+ ++ W + P S H SIT++K ++K+EG Sbjct: 11820 ETETARFETEI-SEEDVHGHWKLKGDALHQSPVISFTPKHYFSITMMKDCEIKEEGTKHM 11878 Query: 802 --VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 +Y ++ + + + ++A + A + +++TV T ++ Sbjct: 11879 LILYNVRMDMAGAVDFSAANAKSKAQLRVKARVIGLLRPLKDVTVTAGETATFDCELSYE 11938 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 +P + W+ + PS+ + +G + L + +V ++G+ K A + + A Sbjct: 11939 GIP-VEWFLGGTKLEPSDRVVTRAEGRSHTLTLRDVKLT-EAGEVKLTAKDFLTQ----A 11992 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978 ++ ++ V F K L+ EE T LEC+ S +W+ + +EI +++ + Sbjct: 11993 QLIVNEPPVEFTKPLEDQ-TVEEEATAELECEVSKEKAEVRWFRDGQEIRKTKKYDMVAD 12051 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 G D C K +TS L V+ EF + L D EVKEK+ A E Sbjct: 12052 GCKRKLVIHDCTLDDSKTYTCDAKHFKTSAFLNVEPPYVEFTKPLHDVEVKEKESARFEC 12111 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 E++ E+A V W RDG I+ K KY+ G R L I + DE EY C R + Sbjct: 12112 EVSRESAKVRWFRDGNEIR-KGKKYEMISEGVKRILIISKSVFDDEAEYECDARTSKSSG 12170 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158 +TVVE L N + + + E++K A V W+K E+ + DG Sbjct: 12171 MLTVVEEEARFTKNLANIEGTETDSVKLICEVSKPSAEVTWYKGDQELPEVGRYEHITDG 12230 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 KK+ L I +DDAGEY C++ S+ T L + E + F R P+ V A Sbjct: 12231 KKRILIIKGLRMDDAGEYHCKLPTSQTTGNLRINELAAEFIAR-PQNQEVVEGEKAQFVC 12289 Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 + +T +V W K + ++ +K+ +IS+ KKR LI++ C D+ + V+L + Sbjct: 12290 SVSKDTYEVKWLKGNTELQSDDKYEIISEGKKRVLIVKNCELKDEGGF--VVLIGTTRAS 12347 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 + V+E +I+ ++ + G + L + +W+ N++ + + Sbjct: 12348 ADLTVLE-KLRIITPLKDTKANEGQETVLNCEVNT-EGAKAKWLKNNETLFESSKFIMVQ 12405 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLEN-NCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 SL IK + +D Y + L N A N+T+ + + I Sbjct: 12406 KDNVFSLRIKDTQKSDEANYTITLTNQRAEQAKSSANITVHE-------------EDLRI 12452 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAV 1456 + ++ + I + ++ T +W+ + IT ++ + + + Sbjct: 12453 VVPPEDVDTQEKKAISFTCKVNRQNVTVQWMKAGQEITLSKRILYRVDKEK----HTLTI 12508 Query: 1457 NEVDISDASETTEYYKVIKETK----IQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQP 1511 + ++D E T K T ++PT L + T ED E +C + Sbjct: 12509 KDCSLADEGEYTVIAGPDKATAELIISEAPTDFTAQLSDQTITEFEDAEFSCEL-TKEKA 12567 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 + WYRDG++++ R +C + T + +++ P Sbjct: 12568 DIKWYRDGREIREGPRYQFERDGKTCRLRIKECRPDDECEYACGVDDKRTRARLFVEETP 12627 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 V I G + +V V EV W +N + +Y + ++ K ++ Sbjct: 12628 V-EIVRPPTDVFEPPGSD-VVYEVELNKDRVEVKWLRNNMTIVQGDKYQMMSEGKIHRLQ 12685 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 + E++ +Y + A + + +E+ P I + + ++ VT KP + Sbjct: 12686 VCEIRPRDQGEYRVIAKDKDARAKLELAAV----------PTI-KTLDQDLVTDAGKPFV 12734 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVAD---VDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 G+ Y + + E N D D Y ++ ++ E +++I QN G Sbjct: 12735 --MGVPYNAYPLAEAEWFYNDISLPKDNIHTSIDRTEYRLKDPKKSEEGRYKIIVQNKHG 12792 Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 EA I +K +DVP D E + I W E +GGS I+ Y VE + Sbjct: 12793 KGEAF----INLK-VIDVPGPVKNLQVVDTADGE-ISIAWEEPESDGGSKILAYVVERRD 12846 Query: 1809 -EGKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 + K W + L ++ Y FR+ ARN +G+ +D + P Sbjct: 12847 VKRKTWTLATDCADSTEYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVP 12906 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 P+N +V T+ W P +GGS IT+YIIE + W ++ Sbjct: 12907 DAPQNVIVGNVNKFGATVSWEPPLFDGGSEITSYIIELRDRTSVVWAPVMVTKPHERSAI 12966 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 I ++ E E IFR+ AEN G+ P+ + + V++ PSPP + ++T Sbjct: 12967 INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMDPIERPSPPLNLTHSEQTKDSCLLT 13026 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 W TP +GG + GY I + W+ L + + L Y R+ A N Sbjct: 13027 -WETPLKNGGTAITGYIIERCEEGTDKWLRCNARLCPDLLYRMSGLKFGKKYSYRVIAEN 13085 Query: 2046 EIGLSEP 2052 G S+P Sbjct: 13086 AAGQSDP 13092 Score = 281 bits (689), Expect = 1e-73 Identities = 327/1448 (22%), Positives = 576/1448 (39%), Gaps = 105/1448 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G +C L P + W G ++ P + + E H L + +VK + Sbjct: 11923 VTAGETATFDCELSYEGIP-VEWFLGGTKLEPSDRVVTRAEGRSH----TLTLRDVKLTE 11977 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPR 763 G + A + +A L + EPP + +PL+ V + + L +V + Sbjct: 11978 AGEVKLTAKDFLTQAQLIV--------NEPPVEFTKPLEDQTVEEEATAELECEV-SKEK 12028 Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W ++ + + K +DG + ++ + D YT A++ + TSA + Sbjct: 12029 AEVRWFRDGQEIRKTKKYDMVADGCKRKL-VIHDCTLDDSKTYTCDAKHFK----TSAFL 12083 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 VE P E +P ++ VKEK + + V+R + W+R+ I + Sbjct: 12084 NVEPPYVEFTKP------LHDVEVKEKESARFECEVSRESA-KVRWFRDGNEIRKGKKYE 12136 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 +G L+I+ + D +Y+C A S KSS +T+ E+ F K+L + E Sbjct: 12137 MISEGVKRILIISKSVFD-DEAEYECDARTS--KSS--GMLTVVEEEARFTKNLA-NIEG 12190 Query: 941 EEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 E +V L C+ S + WY +E+ + E I +G+ D G C Sbjct: 12191 TETDSVKLICEVSKPSAEVTWYKGDQELPEVGRYEHITDGKKRILIIKGLRMDDAGEYHC 12250 Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 + +T+ L + E EFI + Q+ EV E + A ++ +T +V W + G Sbjct: 12251 KLPTSQTTGNLRINELAAEFIARPQNQEVVEGEKAQFVCSVSKDTYEVKWLK-GNTELQS 12309 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 +KY+ G R L ++N + DEG + ++ +A++TV+E IIT L++ K N Sbjct: 12310 DDKYEIISEGKKRVLIVKNCELKDEGGFVVLIGTTRASADLTVLE-KLRIITPLKDTKAN 12368 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 +G + E+ A +W K+ + S+ + L+I D D Y+ Sbjct: 12369 EGQETVLNCEVNTEGAKAKWLKNNETLFESSKFIMVQKDNVFSLRIKDTQKSDEANYTIT 12428 Query: 1180 VGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234 + N +K +A +TV E + + PE + T ++ + + V W K Sbjct: 12429 LTNQRAEQAKSSANITVHEEDLRIVVP-PEDVDTQEKKAISFTCKVNRQNVTVQWMKAGQ 12487 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE 1294 I +++ D +K TL I+ C+ D+ EYT + K+T +L + E P Sbjct: 12488 EITLSKRILYRVDKEKHTLTIKDCSLADEGEYTVIAGPDKATAELIIS--EAPTDFTAQL 12545 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 + I D + + + +W + + I++ + D K+ L IK+ D Sbjct: 12546 SDQTITEFEDAEFSCELTK-EKADIKWYRDGREIREGPRYQFERDGKTCRLRIKECRPDD 12604 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 E CG D + + +P +EI ++ EP S ++Y Sbjct: 12605 ------ECEYACGVDDKRTRARLFVEETP------VEIVRPPTDVF--EPPG---SDVVY 12647 Query: 1415 YVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 V ++ +W+ N+T Q Q + +R + + D + + Sbjct: 12648 EVELNKDRVEVKWLR-NNMTIVQGDKYQMMSEGKIHRLQVCEIRPRDQGEYRVIAKDKDA 12706 Query: 1474 IKETKIQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYEN 1531 + ++ + PT++ +++ T+ + + + P + W Y D K T + Sbjct: 12707 RAKLELAAVPTIKTLDQDLVTDAGKPFVMGVPYNAYPLAEAEWFYNDISLPKDNIHTSID 12766 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-------VITISNEDI---- 1580 R YK I N HG+ E + + P V+ ++ +I Sbjct: 12767 RTEYRLKDPKKSEEGRYKIIVQNKHGKGEAFINLKVIDVPGPVKNLQVVDTADGEISIAW 12826 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 ++ G ++ V+E W + EY +T ++ S K L R + Sbjct: 12827 EEPESDGGSKILAYVVERRDVKRKTWTL-ATDCADSTEYTVTGLQRDS----KYLFRVCA 12881 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 N +V+ K +D P P+ VI+ +++ T+ W+PPL DGG E+T Sbjct: 12882 RNRVGSGPNVETDKAVQAKNK-FDVPDAPQN-VIVGNVNKFGATVSWEPPLFDGGSEITS 12939 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759 Y IE + + W V + I + EN EY+FRV A+N G + + + P+ Sbjct: 12940 YIIELRDRTSVVWAPVMVTKPHERSAIINDVIENKEYIFRVKAENKAGIGKPSAATNPVK 12999 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXX 1818 I ++ PS +S +TW KNGG+ I Y +E +EG KW Sbjct: 13000 IMDPIERPSPPLNLTHSEQ-TKDSCLLTWETPLKNGGTAITGYIIERCEEGTDKWLRCNA 13058 Query: 1819 XX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 R+ L Y +R+ A N G SD +G L P + Sbjct: 13059 RLCPDLLYRMSGLKFGKKYSYRVIAENAAG-----QSDPSNIVGPVLA--DDPHYAPTLD 13111 Query: 1877 STSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 ++ L+ P + PIT Y I T K +T G V E Sbjct: 13112 LSAFKDGLEVFVPNPLSIRVPITGYPI--PTAKWTFGENALTAGDRVSMVTKSTFTELVI 13169 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWD 1993 + + T ++L + SV E V + P+AP L++ V V W PE D Sbjct: 13170 TPSVRADKGTYSLTLENDVASVSGEIEVNVIASPSAPKDLKVAEVTRKHVHLMWEAPEHD 13229 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 GG+P+ GY + R+V++ W++V + ++ + D+ E Y+ R+ A N+ G EP Sbjct: 13230 GGSPITGYQVEKREVSRKTWVKV-MSGLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPA 13288 Query: 2054 ESDEPFKV 2061 ++P V Sbjct: 13289 YIEDPVNV 13296 Score = 266 bits (652), Expect = 5e-69 Identities = 205/773 (26%), Positives = 327/773 (42%), Gaps = 42/773 (5%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 D + ++ + + L V + P+P +W + + + + L I V Sbjct: 24747 DLRKCVTVRASATLRLFVTIRGRPEPEVKWKKADGTLPE--RAQIEVTGSYTGLVIDNVN 24804 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G Y L LENN G +NV +LD PS P + ++ S+ + W+ P+ G + Sbjct: 24805 RFDTGKYVLTLENNIGSKSAFVNVKVLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAK 24864 Query: 1412 IIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I +Y+VE +E + S+ N + + +L+ Y FR AVNE+ + +ETTE Sbjct: 24865 ITHYIVEKRESKRLAFTSITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEA 24924 Query: 1471 YKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 K+ + KI V + ++ E + + I G + V G TA Sbjct: 24925 VKISQAPLPPGKITVIDVTRHTVTLSWEKPDHDGGSKITGYM----VEMMTKGSDKWTAC 24980 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET----SCVVG--IQQKPVITISNEDI 1580 T + ++ A ND G+ + + VV I +P+I + Sbjct: 24981 VTIK-ALEATIEGLTTGEEYSFRITAINDKGKSDPKPLGAPVVARDITIEPIIDLMFNTY 25039 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 K GD+ + G P PEV W K+G+ L+ N+ T + S I IK+ R + Sbjct: 25040 SVK--AGDDLKIDVPFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDA 25097 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 KY I +NT G S E+++ V DKP P G + + EIS + +++ W PP+ DGG ++ Sbjct: 25098 GKYEITLTNTFGVKSAEISVIVLDKPG-PPGAIKVEEISADFISLSWDPPIYDGGCQINN 25156 Query: 1701 YAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y +EK + W I A V R + + +L + EY FR+ A+N G S A++S PIV Sbjct: 25157 YVVEKRDTTTTAWQIVSATVAR--TSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIV 25214 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX 1818 + P + +TW +GGSPI+ Y +E K Q W Sbjct: 25215 AQYPF-TPPGPPTSLQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNR 25273 Query: 1819 XXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 ++ L YQ+R+YA N G + D ++ PPSQPR V Sbjct: 25274 GLITETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPSQPR---VMN 25330 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936 T SV+L WT+PE +GG+ +T YI+E + W K + + E Sbjct: 25331 ITRTSVSLSWTKPEFDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRY 25390 Query: 1937 IFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 FRI A+N G+ S P+ES K PP +E ++ ++ G Sbjct: 25391 DFRIIAKNAAGLFSEPSESTGPVTVKDDV--DPPRITIEDKLRQLVVIKA--------GE 25440 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + I+ R + W + GK +F I + T ++R R + G Sbjct: 25441 ILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLTSTTLIVRDAIRRDSG 25493 Score = 266 bits (651), Expect = 6e-69 Identities = 288/1212 (23%), Positives = 488/1212 (40%), Gaps = 99/1212 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+K+ GS V+ + ++G + WF+ T I++ DD N+ T Sbjct: 5083 PSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRD--------DDPNITT-- 5132 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 TF N A A S + +HG + T A + Sbjct: 5133 ----------TFE---NNIAVLAISNVAI-------NHGGKYTCQAENEAGKQKCEATVT 5172 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 P F +KP V G LEC++ P+ + W G+E+ + + ++ Sbjct: 5173 VQEPARFVEKPPCISVTAGDSATLECKVSGSPDLKVKWFKDGKEMAGGRKYKITFKENV- 5231 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +VLKI + ++ Y V NR G+ + + EPP +S V G Sbjct: 5232 ---AVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINV----LEPPVFSLKPQSQDVIPG 5284 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLK 806 +V+L+A G I W + +K + T K + ++ S+ L K YT + Sbjct: 5285 TTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLE-LHALKPSQSAKYTCQ 5343 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI-KLVARVTRNPVPSIT 865 N G +A + V+ EPP F+ + + G++ L +V +P SI Sbjct: 5344 VSNDAGKVSCTAALFVK-------EPPKFVMKLDLTKLVLNGSLATLECKVAGSPEISIR 5396 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 WY+N I + F L I++ E DSGDY C AS+ AG VT+ Sbjct: 5397 WYKNETEIGSDDKYQMAFTDSVATLRISSCCVE-DSGDYICQASSDAGSDRCSCLVTVK- 5454 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXX 983 E FVK + S E +G V+LE S + + + K+I D R II + Sbjct: 5455 EPPEFVKPFE-SKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRN-DRRHIISLTKDVA 5512 Query: 984 XXXXXXXX-XDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEV-KEKDVAILEV 1038 D G +C V + Q + LV + P F++K+ + V KDV++ V Sbjct: 5513 ALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPSFVQKMDNTNVLLAKDVSLQCV 5572 Query: 1039 EINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095 S + W +D IK ++ + FE + + +YI + + G+Y+C ++E+ Sbjct: 5573 LKGSMPMTISWMKDDHEIKESEHVQISFENQTAV--IYISSVQLKHGGKYTCHAQNEAGS 5630 Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152 CTA +TV E P I + ++ V + AT E + L +W KDG+E+ Sbjct: 5631 QKCTAVLTVKE-PANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNELTSGRKY 5689 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFI 1206 ++ LKI + DAGEY+ EV G S C A++TV + I +FT +L E Sbjct: 5690 KIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFTRKLKETE 5749 Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + + + ++VTW+K+ IE EK I +L I + D Y Sbjct: 5750 SIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLEISRLDSSDSGNY 5809 Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 TC+ + + + + V+ PP I++ + GS V V P W ++ Sbjct: 5810 TCIAKNQAGSDQCSGTLKVKEPPSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDT 5869 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 K + + S+S+ + + +D+G Y + N+ G + + + + P Sbjct: 5870 KEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDSCQATLFVKEPPKFTR 5929 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEI---DTTEWISVKNITKTQTSIQ 1441 KP + + S + + E + TG I Y+ + +I D + V ++ + + Sbjct: 5930 KPEKITVVKPSQLVVF-ECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSLARLEIISS 5988 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 ++K + Y A NE SE+ +KE P + KPL + + Sbjct: 5989 DIKDSGVYYCEAR--NEA----GSESCSMDLRVKE----PPVLVKPLSPLEVVNGSNAYF 6038 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 C+ G +VTW +D K +K++ ++ Y+CI N+ Sbjct: 6039 ECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQCIVANEV 6098 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + + I++ P E++ +G V+ G PP + W K+ + + D Sbjct: 6099 GSCSSQSTLSIKEPPSFVERIENVVT--VLGKMVEFKCVVRGSPPLSIQWQKDESWILED 6156 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 T + + + I + HS KYT +A N AG TL V + P E P ++ Sbjct: 6157 PSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEKPEVIN 6216 Query: 1677 EISRESVTIEWK 1688 + + V+ E K Sbjct: 6217 VTAGDPVSFECK 6228 Score = 260 bits (636), Expect = 4e-67 Identities = 221/844 (26%), Positives = 361/844 (42%), Gaps = 54/844 (6%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLLDAKSTTKL--- 1279 D+T Y ++ + + +++T+++ + T I TE+ + + L+ + + Sbjct: 21422 DITGYIVETCLPEEDEWTIVTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEPASV 21481 Query: 1280 ----KVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 K E PP+I D + I+ S + L V + P P W + + + Sbjct: 21482 PGSPKAEDRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRW--SREKGEPLD 21539 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 I +L I+ V+ D G Y L +EN+ G +NV +LD P P I EI Sbjct: 21540 RASIEITPSFTTLLIENVDRFDGGKYMLTVENSSGTKTAFINVRVLDTPGAPQNLTIKEI 21599 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYR 1450 S+++ WD P G S I +Y+VE +E T + S+ N + KT I +L+ + Y Sbjct: 21600 TKDSVSLIWDPPVIDGGSRIRHYIVEKRE-STRKAYSIVNASCPKTSWRIGDLQEGNLYF 21658 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVP 1509 FR A NE + ET E K I E + P + LK +T+ E GG Sbjct: 21659 FRILAENEYGVGLPVETMEAIK-ISERPL--PPGKVTLKEVTSNSVTLSWEKPDHDGG-- 21713 Query: 1510 QPKVTWY---RDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSC 1563 ++T Y GK K + ++ A N+ G + Sbjct: 21714 -SRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQGEEYSFRISATNEKGISDPRPLS 21772 Query: 1564 VVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 V I + VI + + + V GD+ + P V+W K+G L+ N Sbjct: 21773 VPVIAKDVVIAPAFKLLFSTFSVLAGDDLKIDVPYVAQPKAAVVWQKDGISLKETTRVNT 21832 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 E+ + +KE R KYTI+ +N+AG ++ ++ + V DKP P GP+ + E++ + Sbjct: 21833 EVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVLDKPGPPTGPIKIEEVTAD 21892 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFR 1740 SVT+ W+PP +GG + Y +EK + W I A V R T +L CEY FR Sbjct: 21893 SVTLSWQPPEYEGGCSINNYIVEKRDTSTTNWQIVSATVAR--TTTKAARLKTGCEYQFR 21950 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 + A+N G S + SE +V + ++P ES+ + W +GGS I+ Sbjct: 21951 IAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSA-TKESMVVVWNKPSSDGGSKIL 22009 Query: 1801 DYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 Y +E K++ W R I L Y+FR+YA N +G S + Sbjct: 22010 GYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFRVYAENIVGLSKASKVSEIQ 22069 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 PP +P +V S SVTL+WT P+ +GG IT Y++E K + W K Sbjct: 22070 VARDPCDPPGKPEAVIVKRS---SVTLRWTPPQFDGGIKITGYVVEKKELPNGRWMKASF 22126 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976 E + + E+ + FR+ A N GV S+P++S K PP L+ + Sbjct: 22127 ANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKDEV--DPPQIDLDAK 22184 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 N+V+ + + D G +LG + + W++ G+ NT + I++ T Sbjct: 22185 -YSQNVVVNAGESFRIDAG--ILG-----KPIPSVHWIKSGEELTNTARLEIKNTDFTTT 22236 Query: 2037 YMIR 2040 ++ Sbjct: 22237 LSVK 22240 Score = 249 bits (610), Expect = 6e-64 Identities = 182/672 (27%), Positives = 294/672 (43%), Gaps = 31/672 (4%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G + + + ++ P P W + + D LTI + DAG Y Sbjct: 23671 VHAGGSMRINIPFKGRPIPEINWTKDDGDLPDKAQIDKGPDF--THLTINICDRNDAGKY 23728 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 L L+N+ G ++V +LD P P + +I + + + W+ P G S I Y+++ Sbjct: 23729 TLTLQNSAGTKSAFVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIID 23788 Query: 1419 YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV---- 1473 +E + ++ +KT + +L Y FR A NE I ET E K Sbjct: 23789 KRESTRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPP 23848 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGKKLKTAKATYEN 1531 + K+ V K +++ + + + I G QPK G + + AT Sbjct: 23849 LSVGKVTLTDVTKTTASLSWDKPDHDGGSRILGYYIEMQPK------GSE-EWIVATVCK 23901 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQKPVITISNEDIKQKHKV--G 1587 + +A+N+ G+ + + I + I S + + V G Sbjct: 23902 TCEGTVAGLSSGQEYLLRVLAYNEKGKSDPRPLASPVIAKDVTIEPSFKLTFNTYSVQSG 23961 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 ++ V +G P P++ W K+G L+ N+++ ++V++IKE R S KYTI A Sbjct: 23962 EDLKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITA 24021 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 +N GT + EV + + DKP P GPV + E+S V I W+PP+ GG ++ Y +EK + Sbjct: 24022 TNNIGTVTEEVAIIILDKPGPPTGPVKIDEVSATYVVISWEPPVYTGGCQINNYVVEKRD 24081 Query: 1708 PDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 W V A + R T I KL EY FRV A+N G S +++S P+V+ Sbjct: 24082 TTTTNWQTVSATIAR--TTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTE 24139 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR 1825 P+ + + + I W P NGGSPII Y +E K++ W R Sbjct: 24140 PA-APGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTR 24198 Query: 1826 IQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883 ++ L Y++R++A N G S + + PP P V+ T +T Sbjct: 24199 LRTNGLEEGIEYEYRVFAENIAGISPSSKVSESVVARDPCDPPGTPEAIVI---TRNLIT 24255 Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 L+WT+P+ +GGS IT YIIE K + W K + I + E+ FR+ A Sbjct: 24256 LQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQFTITGLHEEQRYEFRVIAR 24315 Query: 1944 NTVGV-SLPTES 1954 N G+ S+P+ES Sbjct: 24316 NAAGILSVPSES 24327 Score = 249 bits (609), Expect = 7e-64 Identities = 181/674 (26%), Positives = 297/674 (44%), Gaps = 34/674 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAG 1356 +K GS TL V ++ P P+ W N + + SID+ S+TI++ D+G Sbjct: 25833 VKDGSSFTLRVPFKGKPVPHVMW--NKPDVDL--RVRASIDTTDTCTSVTIEQATRDDSG 25888 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y + L+N G A + ++V +LD P PP + E+ SS I WD P+N G + + Y+ Sbjct: 25889 KYTVTLQNVAGTATLTLSVKVLDSPGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYL 25948 Query: 1417 VEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 V+ +E W + N T + NL+ Y FR NE + ET E K+ Sbjct: 25949 VDLREATKMGWSRISNSCPRLTYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEGTKI-- 26006 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGK----KLKTA 1525 T+ SP P +T E + L + GG + V G+ K + Sbjct: 26007 -TEKPSPP---PKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCGST 26062 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH 1584 K+T+ +D ++ +V Q + P I + + + Sbjct: 26063 KSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKDQLEAPEINMKDFQHNTAY 26122 Query: 1585 -KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 K G + + G P P+V K+G L++ +N + +I ++E S + +Y Sbjct: 26123 VKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESVASDAGRY 26182 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 I ASN+ GT+ V + V D+P GPV M +I+ +SV+++W PP DGG +T Y + Sbjct: 26183 DITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV 26242 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 K E WI+V+ T I KLN EY FR+ A+N G SE ++S+ + + Sbjct: 26243 LKRETTTANWIEVSSAVARC-TIKIMKLNTGVEYQFRIKAENRFGISEHIDSQTVTVSLP 26301 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822 +P + ES+ + W +GGS + Y +++K W+ Sbjct: 26302 YTLP-VAPSQPWVSAVTKESIVVNWKEPSSDGGSHVFGYHLQMKDRNSILWQKVNTTVIR 26360 Query: 1823 XARIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 + ++N Y+F++ A N G S D + PP+ R V++ T Sbjct: 26361 ATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPNSVR---VTDITKN 26417 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 S++L W +P +GGS IT Y+IE K W+K + + + + + + FR+ Sbjct: 26418 SISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRV 26477 Query: 1941 SAENTVG-VSLPTE 1953 A+N VG VS P+E Sbjct: 26478 MAKNAVGSVSNPSE 26491 Score = 246 bits (603), Expect = 4e-63 Identities = 177/692 (25%), Positives = 307/692 (44%), Gaps = 33/692 (4%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 RE + G+ + ++ + P P W N + + S + L ++ TD Sbjct: 16895 RELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETS--GTTTKLEMRYCNRTD 16952 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 G Y L +EN G V +LDKP P + ++ S S + W +PE+ G + I Sbjct: 16953 CGDYTLTVENPAGSKIATCTVLVLDKPGPVQHLRVSDVRSDSAQLSWKDPEDNGGARITN 17012 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +VVE ++ + +W+ + + +K ++ + ++L +SY FR A N+ S+ ETT+ K Sbjct: 17013 FVVEKKDAASPQWVPICSSSKKRSMMAKHLIEGTSYMFRVAAENQFGRSEYVETTKAIKA 17072 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGKK----LK 1523 + + P K L ++ + E + L + GG + V + +G+K K Sbjct: 17073 MNP--LFPPGPPKDLHHVDADKTE-VWLQWNWPDRTGGSDITGFLVEYQEEGEKDWIVFK 17129 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583 T + I + +T+ V Q+K V I D+K Sbjct: 17130 TVSIPECHVTGLEEGKTYRFRVKTENAIGLS---RPDTTVPVLCQEKLVPPIVEVDVKLI 17186 Query: 1584 H----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 K G + A++ G+P P W +G +++++ I T ++V+ I + R+H Sbjct: 17187 EGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKIDTDNFSTVLSIADCTRNH 17246 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 + Y + SN+AG+ +V + + V D P+ P GPV + E++ +S+ I+W+PP DDGG + Sbjct: 17247 TGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILEVTPDSMVIDWRPPKDDGGSPVM 17306 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y +EK E + W V+ I +L + EY+ R+ A+N +G ALES P V Sbjct: 17307 NYIVEKRESNKETWGGVSSGSTSTRLK-ISRLQQGVEYVVRIRAENKMGIGAALESAPTV 17365 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX 1819 + + P + +++ + W +GGSPI Y +E + +G KW Sbjct: 17366 ARHQFEAPG-HPGKPVASDLSEDALTLGWTMPLFDGGSPISGYIIERRHKGGKWIRVNKT 17424 Query: 1820 XXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 R + L + Y+FR++A N G S P D + +T P P N V + Sbjct: 17425 PCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSPVSDPAKPCRPITVPGPPVNPKVKDY 17484 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC---IENIKEKD 1934 + L W +P +GGSP+ YI+E + G W K+ + + C ++ + E Sbjct: 17485 SCTYADLVWIKPTKDGGSPVLGYIVECQK-GGAEWEKVNK--DDLIKQCAYRVKGLTEDT 17541 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 E FR+ A N +G E + K +P Sbjct: 17542 EYRFRVKAVNMIGEGETREIPESVIAKDIIIP 17573 Score = 241 bits (590), Expect = 1e-61 Identities = 252/1059 (23%), Positives = 416/1059 (39%), Gaps = 69/1059 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F +K V D+ L+C L I+W+ EI E++ ++ E+ Sbjct: 5549 PPSFVQKMDNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQT---- 5604 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +V+ I++V+ G YT A N G VL +K EP + E KS+ V + Sbjct: 5605 AVIYISSVQLKHGGKYTCHAQNEAGSQKCTAVLTVK----EPANITEQAKSVSVTVRDPA 5660 Query: 753 ILSAQVVGNPRPTITWCKN-NKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENS 810 L + G W K+ N+ K DT SI + + D G YT + N Sbjct: 5661 TLECRYSGTKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSND 5720 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRN 869 G + AV+TV + + P F + +E T KG+ + + +P ++TW++ Sbjct: 5721 AGRSSCEAVVTVLDQIIK----PSFTRKLKE-TESIKGSFTQLECLVSGSLPINVTWFKE 5775 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 N+ I E F L I+ +DS DSG+Y C+A N AG T+ V++ Sbjct: 5776 NKEIEADEKHKCIFFENAASLEISRLDSS-DSGNYTCIAKNQAGSDQCSG--TLKVKEPP 5832 Query: 930 FVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + +S + G V S T ++ W+ + KE+S + + Sbjct: 5833 SIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELF 5892 Query: 988 XXXXXDVGVIKCIVKDQETS----TMLVVKETIPEFIRKLQDFEV-KEKDVAILEVEIN- 1041 D G C V + S L VKE P+F RK + V K + + E +I Sbjct: 5893 FAKPSDSGQYVCEVSNDVGSDSCQATLFVKEP-PKFTRKPEKITVVKPSQLVVFECQITG 5951 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097 + D W +DG I P +KY + +L I ++ + D G Y C R+E SC+ Sbjct: 5952 TPEIDTYWFKDGNDISPS-DKYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCS 6010 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFS-NHIQL 1154 ++ V E PP ++ L +V G+ A FE L KG A V W KD +I+ S H+ L Sbjct: 6011 MDLRVKE-PPVLVKPLSPLEVVNGSNAYFEC-LVKGTAPFEVTWEKDSKDIKSSLKHVIL 6068 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 + L + CD D GEY C EVG+ + L+++EP +F R+ + V Sbjct: 6069 QKNDSIITLDVQKCDALDVGEYQCIVANEVGSCSSQSTLSIKEPP-SFVERIENVVTVLG 6127 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 + V L + W K +S I + + TL I C +YTC Sbjct: 6128 KMVEFKCVVRGSPPLSIQWQKDESWILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQA 6187 Query: 1271 LDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-II 1328 ++ K VV+ PP+I++ + G V+ P+ +W + K +I Sbjct: 6188 MNEAGQEKCFSTLVVQEPPQIIEKPEVINVTAGDPVSFECKVSGTPELKVKWSKDGKEVI 6247 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 +H+ I++ S L ++ V+ D G Y + N+ ++ + +L++ PP Sbjct: 6248 PSRQHSLSYINNVS-QLKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPP---- 6302 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 S I + E G + I + T EW +T + L+ +S Sbjct: 6303 ------SFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKDGTKLSGRTKHKILQDENS 6356 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 + + D + T K + + ++ PN + F G Sbjct: 6357 VSLDIECLEKAD----TGTYTCKLANKAGSCECSGTLRVKESQAVIPNTTVRFKGSFKGT 6412 Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 P V W++D +L + + + + G SC + Sbjct: 6413 PPFTVKWFKDDTELICGPSCFTGLEGLSCFLDLF-------AVGISHSGTY--SCQISND 6463 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 +P + + K+G+ + + G P + WYKN L + +T + Sbjct: 6464 AEPPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISWYKNDAILSDGGNLRMTFDNSVA 6523 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 V+ I + YT EA N AGT S L + + PS Sbjct: 6524 VLEISTSSFDDNGVYTCEAQNDAGTKSCSTALTIKEPPS 6562 Score = 237 bits (581), Expect = 2e-60 Identities = 258/1102 (23%), Positives = 449/1102 (40%), Gaps = 69/1102 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+F K ++ V G+ + LEC++ I W+ G+++ + +A E + + Sbjct: 4803 PSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFEEKI----A 4858 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESV 752 L I K GTYT A N G +S + ++ EPP ++ L+ I+ +QG S Sbjct: 4859 CLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQ----EPPVFVKRLEPKILWKQGMSS 4914 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810 LS V G+P +TW N+KP+ + K T+ T+ + D G YT + N Sbjct: 4915 RLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNE 4974 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G S+ +TV+EP P F + + V + T L +T ITW+++ Sbjct: 4975 AGCESCSSQVTVKEP-------PAFKKELRLVEVVKGCTAHLECEMTGTAPFEITWFKDK 5027 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 +S S+T E + D GDY+C SN GK + A + + +F Sbjct: 5028 NPVS-SDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLK-DPPSF 5085 Query: 931 VKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987 VK ++ + G V L+ + S ++ +W+ + + + D E Sbjct: 5086 VKKVENTTAVL-GSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAIS 5144 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVEIN-SE 1043 G C +++ T+ E F+ K V D A LE +++ S Sbjct: 5145 NVAINHGGKYTCQAENEAGKQKCEATVTVQEPARFVEKPPCISVTAGDSATLECKVSGSP 5204 Query: 1044 TADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYI--RNTSVHDEGEYSCILRDESCTAEV 1100 V W +DG E+ +K K F++ + K+ R S + E S + E C+ + Sbjct: 5205 DLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSI 5264 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDG 1158 V+E PP + Q+Q V G T G A +++WF++ E+ + + Sbjct: 5265 NVLE-PPVFSLKPQSQDVIPGTTVVLTAAFT-GTAPFMIKWFREDKEMLTGGTCFIKKET 5322 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 L+++ + +Y+C+V N CTA L V+EP F ++L LV + A Sbjct: 5323 NSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPP-KFVMKLDLTKLVLNGSLA 5381 Query: 1215 YLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLD 1272 L ++ + + WYK ++ I +K+ + TL I C +D +Y C D Sbjct: 5382 TLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQASSD 5441 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 A S + V+ PP+ V I +G+DV L +SK I+ + Sbjct: 5442 AGSDRCSCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDR 5501 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 S+ A+L I K E DAG Y+ + N G + VT+ + PS + ++ Sbjct: 5502 RHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPS-----FVQKM 5556 Query: 1393 DSSSINICWDEPENT---GNSTI-IYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNS 1447 D++++ + D G+ + I ++ + EI +E + + +T I +++ Sbjct: 5557 DNTNVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLKH 5616 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 ++ +A NE S+ +KE + + K+++ + L C + G Sbjct: 5617 GGKYTCHAQNEA----GSQKCTAVLTVKEPA----NITEQAKSVSVTVRDPATLECRYSG 5668 Query: 1508 VPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 K W +DG +L + + + + Y ND G Sbjct: 5669 TKVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEA 5728 Query: 1564 VVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 VV + + + +K+ + G + ++ G P V W+K ++E D+++ Sbjct: 5729 VVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCI 5788 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEG-PVIMREI 1678 E + + I L S S YT A N AG+ TLKV + PS KPE VI Sbjct: 5789 FFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPSIIEKPESQDVIPGSK 5848 Query: 1679 SRESVTIEWKPPLDDGGLELTK 1700 + +V + PPL + TK Sbjct: 5849 VQFNVLLSGTPPLTINWFKDTK 5870 Score = 237 bits (579), Expect = 3e-60 Identities = 184/721 (25%), Positives = 307/721 (42%), Gaps = 37/721 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTS 1439 P PP + +S I + W+ P+ G + I Y+V+ + T +W + + + + Sbjct: 13303 PDPPENLKWRDKSASKIFLSWEPPKWDGGTPIKGYIVDKCQRGTDKWEPCGDPMPELKFE 13362 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPN 1496 + L Y +R A+N++ S ++T+ +++ + P ++ K L +T + Sbjct: 13363 VTGLIEGQWYAYRVRALNKLGASKPCKSTD--EILAVDPKEPPEIQLDAKLLAGLTAKAG 13420 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIA 1552 IEL G P+PKV W + LK T Y A Sbjct: 13421 TKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKRDDTATYIIEA 13480 Query: 1553 FNDHGEVETSCVVGIQQKP-------VITISNEDI----KQKHKVGDEWLVTAVIEGIPP 1601 N G + V I KP + I+NE G + ++E Sbjct: 13481 VNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNYIVERKAV 13540 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 IWYK + ++ TT + T ++ KE ++ A + + + Sbjct: 13541 DSEIWYKLSSTVKQ------TTYKATKLVAFKEYIFRVYAENQFGIGAPAEHAPI-IARY 13593 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 +D P P + +I++++VT+ W P +DGG +T Y +E++EPD+++WI+ + Sbjct: 13594 PFDTPGPPY-KLEPSDIAKDAVTLSWYEPDEDGGSPITGYWVERYEPDHDKWIRCNKLPI 13652 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780 + ++ L +Y FRV+A+N G + + E++ I+IK +D P + Sbjct: 13653 RDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPID-PPWAPGKPTVKDVA 13711 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQK-LSINTTYQFR 1838 S ++ W E +GG+ I Y VE+ + G +W K L Y FR Sbjct: 13712 KTSAFLQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSLEHFLKGLMEKQEYSFR 13771 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 + A N G S P D + + L PPS PR +V S+ S LKWT PE +GGSPIT Sbjct: 13772 VRAVNVAGESEPSEPSDPVLCKERLNPPSPPRWLLVVSSSRNSAELKWTAPERDGGSPIT 13831 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 NYI+E + V+ K W + T + ++ + + E +FR++AEN VG S E + Sbjct: 13832 NYIVEKRDVRRKGWQAVDTTVKEL-KYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSV 13890 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 L K P L I V V W P+ DGG P+L Y I ++ T W++ GK Sbjct: 13891 LAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKSGK 13950 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078 + + D+ E ++ A NE G+ P EP ++ E P ++ Sbjct: 13951 TSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHP---SEPTDIVVIEDPTGPPSPPQELH 14007 Query: 2079 V 2079 + Sbjct: 14008 I 14008 Score = 236 bits (578), Expect = 4e-60 Identities = 267/1198 (22%), Positives = 479/1198 (39%), Gaps = 99/1198 (8%) Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P+FV++L PK G + + C V+G P +TWF + S+ ++ + N ATL Sbjct: 4896 PVFVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKT-NQATL 4954 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I ++ D+G +TC E++ EA S++TV Sbjct: 4955 EIIDLSESDSGNYTC-------------EVMNEAGCESCSSQVTVKE------------- 4988 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 PP F K+ + V +G LEC + +I W FK + V + + + Sbjct: 4989 ----PPAFKKELRLVEVVKGCTAHLECEMTGTAPFEITW-FKDKNPVSSDTKYNIVSKET 5043 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 Y L+I + G Y N G+ + V K+K +PP ++ +++ Sbjct: 5044 AAY---LEIKTFESADVGDYQCCISNDVGKITTKAVAKLK----DPPSFVKKVENTTAVL 5096 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKV--KDEGVYTL 805 G +V L + G+ T+ W K+ + V+ P + ++I +L V G YT Sbjct: 5097 GSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKYTC 5156 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +AEN G + A +TV+EP +PP +T + T++ +V+ +P + Sbjct: 5157 QAENEAGKQKCEATVTVQEPARFVEKPPCI-----SVTAGDSATLE--CKVSGSPDLKVK 5209 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W+++ + ++ F EN+ ++ DS +YK SN GK + + Sbjct: 5210 WFKDGKEMAGGRKYKITFK-ENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINVLE 5268 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXX 983 V +K +S + G TV+L + T KW+ KE+ I +E Sbjct: 5269 PPVFSLK--PQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSS 5326 Query: 984 XXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEV 1038 C V + + L VKE P+F+ KL + V +A LE Sbjct: 5327 LELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEP-PKFVMKLDLTKLVLNGSLATLEC 5385 Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095 ++ S + W ++ I +KY + L I + V D G+Y C ++ Sbjct: 5386 KVAGSPEISIRWYKNETEIG-SDDKYQMAFTDSVATLRISSCCVEDSGDYICQASSDAGS 5444 Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152 C+ VTV E PPE + +++++ KG E ++ + FKD +I+ Sbjct: 5445 DRCSCLVTVKE-PPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDRRH 5503 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPEFILV 1208 +++ L+I + DAG+Y C VGN + C ++T++EP +F ++ ++ Sbjct: 5504 IISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPP-SFVQKMDNTNVL 5562 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 A + V + ++W K I+++E + + + + I +YTC Sbjct: 5563 LAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLKHGGKYTC 5622 Query: 1269 VLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + + K V V+ P I + + + TL Y +W+ + Sbjct: 5623 HAQNEAGSQKCTAVLTVKEPANITEQAKSVSVTVRDPATLECRYSGTKVLKAKWLKDGNE 5682 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 + + K S+ L I E +DAG Y + N+ G + E VT+LD+ P Sbjct: 5683 LTSGRKYKIQSSDTSSILKILSAEKSDAGEYTFEVSNDAGRSSCEAVVTVLDQIIKPSFT 5742 Query: 1388 NILEIDSSSINICWDEPENTGNSTI---IYYVVEYQEIDTTE---WISVKNITKTQTSIQ 1441 L+ ++ SI + + E + ++ + + E +EI+ E I +N + I Sbjct: 5743 RKLK-ETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASLE--IS 5799 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 L ++ S + A N+ S T + +KE +EKP ++ P ++ Sbjct: 5800 RLDSSDSGNYTCIAKNQAGSDQCSGTLK----VKEPP---SIIEKP-ESQDVIPGSKVQF 5851 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX--XXXXXYKCIAFNDHG 1557 + G P + W++D K++ + + +N Y C ND G Sbjct: 5852 NVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVG 5911 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 + +++ P T E I K + I G P + W+K+GN + Sbjct: 5912 SDSCQATLFVKEPPKFTRKPEKITVV-KPSQLVVFECQITGTPEIDTYWFKDGNDISPSD 5970 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP--SKPEGPV 1673 +Y +T + + + I S Y EA N AG+ S + L+V + P KP P+ Sbjct: 5971 KYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSPL 6028 Score = 234 bits (573), Expect = 2e-59 Identities = 200/756 (26%), Positives = 322/756 (42%), Gaps = 47/756 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284 V W K +++T + + L++++ T DD +YT + ++ ++T + V V+ Sbjct: 21815 VVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVIVL 21874 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSIDSKS 1342 + P +I+ + ++ + +Q P+ +N+ I++K T I S + Sbjct: 21875 DKPGPPTG---PIKIEEVTADSVTLSWQP-PEYEGGCSINNYIVEKRDTSTTNWQIVSAT 21930 Query: 1343 ASLTIKKVENTDAGI-YKLRL--ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDS 1394 + T K G Y+ R+ EN G + V ++ ++ + P PPG P + Sbjct: 21931 VARTTTKAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSATK 21990 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452 S+ + W++P + G S I+ Y +E +E ++ W+ I T+ I L+ Y FR Sbjct: 21991 ESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFR 22050 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQ 1510 YA N V +S AS+ +E I+ + KP I + + T GG+ Sbjct: 22051 VYAENIVGLSKASKVSE----IQVARDPCDPPGKPEAVIVKRSSVTLRWTPPQFDGGI-- 22104 Query: 1511 PKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG--EVETS 1562 K+T Y KK + KA++ N Y + IA N G V + Sbjct: 22105 -KITGYVVEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSD 22163 Query: 1563 CVVGIQQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 I K + D+ K+ G+ + + A I G P P V W K+G +L N Sbjct: 22164 STGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELTNT 22223 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 I + T+ + +KE R +YT+ N G SV + +KV D+P P+GP+ + Sbjct: 22224 ARLEIKNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEKSVIINVKVLDRPGPPDGPISIY 22283 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 ++ E I WK PL DGG E++ Y +E+ E W V ++ I KL E Sbjct: 22284 GVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLVW-TVVELKVQTLNLKITKLLPGNE 22342 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y+FRVI N G E LES+P++ P I +S+ ITW +GG Sbjct: 22343 YIFRVIPVNKYGIGEPLESDPVIAANPFVTPE-APSNVEVSNITKDSMVITWERPTNDGG 22401 Query: 1797 SPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTS 1853 S I Y VE + +EG +W R + + +Y+FR+ A N G P Sbjct: 22402 SAITGYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLLEMRSYEFRVSAENAAGVGKPSPP 22461 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + P P N V+ + SV L W++P +GG I +YI+E V W Sbjct: 22462 TVYFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWV 22521 Query: 1914 KIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGV 1948 G + + EK E FRI A N +GV Sbjct: 22522 MCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGV 22557 Score = 234 bits (573), Expect = 2e-59 Identities = 195/769 (25%), Positives = 337/769 (43%), Gaps = 49/769 (6%) Query: 1216 LTVEIPDE---TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 L VEIP + T + W K +++T + + S L I++ +D +YT + Sbjct: 23964 LKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATN 24023 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 T +V ++ K +I S +++ ++ P +N+ +++K Sbjct: 24024 NIGTVTEEVAIIILD-KPGPPTGPVKIDEVSATYVVISWEP-PVYTGGCQINNYVVEKRD 24081 Query: 1333 HTKPSIDSKSASL---TIKKVENTDAGIYKLRL--ENNCGHA-DVEMNVTILD----KPS 1382 T + + SA++ TIK + Y+ R+ EN G + ++ ++ +P+ Sbjct: 24082 TTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFTEPA 24141 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSI 1440 PG P + + + I W P N G S II Y +E +E ++ W + IT T+ Sbjct: 24142 APGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDTRLRT 24201 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT---- 1493 L+ Y +R +A N IS +S+ +E V+ P + + +N+ T Sbjct: 24202 NGLEEGIEYEYRVFAENIAGISPSSKVSE--SVVARDPCDPPGTPEAIVITRNLITLQWT 24259 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCI 1551 +P D + I G + + K DG+ +K A++ N Y + I Sbjct: 24260 KPQYDGG-SVITGYIIERKKL--PDGRWMK---ASFTNIIDTQFTITGLHEEQRYEFRVI 24313 Query: 1552 AFNDHGEV----ETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPE 1603 A N G + E++ + Q + + D + K K GD + + + I G P P+ Sbjct: 24314 ARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPD 24373 Query: 1604 VIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++W K+G ++++ I + +V+ +K+ R + + SN GT V + +KV Sbjct: 24374 IVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGGTKQVPINVKV 24433 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 D+P P+GP+ + ++ E + W P DGG ++ Y IEK E W V + Sbjct: 24434 LDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSW-TVVEPKIQ 24492 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 +Y + KL EY+FRV+A N G E LESEP++ K + P I + Sbjct: 24493 AISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESEPVLAKNPFNKPG-PPSTPEASAITRD 24551 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQK--LSINTTYQFRI 1839 S+ +TW E +GGS I + +E + +EG +W R + L+ Y+FR+ Sbjct: 24552 SIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLNDLRFRATGLTEGHFYEFRV 24611 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N G P + PP P N V++ +S +V+L W+ P +GG+P++ Sbjct: 24612 SAENAAGVGTPSEPSEYYKACDATYPPGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSG 24671 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVG 1947 YI+E K + WT G H ++ +KE E FRI A N G Sbjct: 24672 YIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEG 24720 Score = 234 bits (572), Expect = 2e-59 Identities = 183/680 (26%), Positives = 283/680 (41%), Gaps = 39/680 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K G+ + + V + P P W + +K H + + I + DAG Y Sbjct: 20424 VKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTT--ESYTLVVIPECTRYDAGKY 20481 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 L LEN G +NV ++D P PP EI SI + W+ P G S I Y++E Sbjct: 20482 VLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHSITLQWEIPLIDGGSKIKNYIIE 20541 Query: 1419 YQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E + + N K I +L+ + Y FR A NE+ I + +ET + + + Sbjct: 20542 KREATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIRASQAP 20601 Query: 1478 KIQSPTVEKPLKNIT-----TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKAT 1528 + + T T+P D GG ++T Y +LK A T Sbjct: 20602 SAPDDLIVTDVSKDTATLAWTKPKHD-------GG---SRITGYVIEAQLKDSDQWAHVT 20651 Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQKH- 1584 ++ A N G E + VV +Q I QK Sbjct: 20652 TIKALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTV 20711 Query: 1585 --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K GD V + G P P V+W K +L+ + NI ++++ I E+KR + Sbjct: 20712 VAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQ 20771 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y++ N GT + +T++V+D P P GP+ + E+S + V I W+ P +DGG+ + Y Sbjct: 20772 YSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNYI 20831 Query: 1703 IEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761 +E E W+++ A V R T+ +L EY FRV AQN G + S P+V Sbjct: 20832 VEMRETTGTSWMELAATVIR--TTFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAA 20889 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820 DVP +++ I+W +GGSPI+ Y +E K++ W+ Sbjct: 20890 YPFDVPG-QPGIPQIVAFTKDAMTISWNEPSSDGGSPILGYHIERKEKNSILWQRISKAV 20948 Query: 1821 XXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + L Y+FR+ A N G S + + PPSQP V T Sbjct: 20949 VVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSEMTYALDPVDPPSQP---VALNIT 21005 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 VTL+WT+PE +GG IT Y +E + + W K + + E F Sbjct: 21006 RHEVTLQWTKPEGDGGFSITGYTVEKRELPNGRWLKANFSNILETNFTVSGLTEDVSYEF 21065 Query: 1939 RISAENTVG-VSLPTESQSV 1957 R+ A N+ G VS P++ V Sbjct: 21066 RVLARNSAGAVSKPSKPSEV 21085 Score = 232 bits (567), Expect = 9e-59 Identities = 199/758 (26%), Positives = 325/758 (42%), Gaps = 45/758 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVV 1284 V W K+ ++ T++ + + L I + D +Y+ + T + V+V Sbjct: 20733 VVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQYSMTGKNILGTVTENITVQVH 20792 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P ++ S +L+ ++A P+ + +N+ I++ + T S +A+ Sbjct: 20793 DIPGPPTG---PIKLDEVSCDYVLISWEA-PENDGGVPINNYIVEMRETTGTSWMELAAT 20848 Query: 1345 L--TIKKVENTDAGI---YKLRLENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDS 1394 + T K GI ++++ +N G + ++ D P PG P I+ Sbjct: 20849 VIRTTFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAAYPFDVPGQPGIPQIVAFTK 20908 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFR 1452 ++ I W+EP + G S I+ Y +E +E ++ W IS + L +Y FR Sbjct: 20909 DAMTISWNEPSSDGGSPILGYHIERKEKNSILWQRISKAVVVGNMFKSSGLMDGIAYEFR 20968 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--IT---TEPNEDIELTCIFGG 1507 A N +S AS+ +E + S V + +T T+P D + Sbjct: 20969 VIAENLAGLSKASKPSEMTYALDPVDPPSQPVALNITRHEVTLQWTKPEGDGGFSITGYT 21028 Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETS--- 1562 V + ++ +G+ LK A + N Y + +A N G V Sbjct: 21029 VEKRELP---NGRWLK---ANFSNILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKP 21082 Query: 1563 -----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 C I++ + ++ K GD + + A + G P P ++W K+G +LE+ Sbjct: 21083 SEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTGRPIPSIVWTKDGKELEDTA 21142 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 + I T + S + K+ R YT+ ASN G + +KV D+P PEGP+ + + Sbjct: 21143 KMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGGFAKFVFNVKVLDRPGPPEGPLHVTD 21202 Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 ++ E + W PPL DGG ++ Y I++ E W VA D V Y + KL + EY Sbjct: 21203 MTVEKCVLSWLPPLHDGGGKIEYYIIQRRETSRLTWTNVA-TDLQVNRYKVTKLLKGNEY 21261 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 +FRV+A N G E LESEP + T VPS I +S+ + W E NGGS Sbjct: 21262 IFRVMAVNKYGVGEPLESEP-AVATNPYVPSDPPQAPEVTAITKDSMVVCWGHPEYNGGS 21320 Query: 1798 PIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 I Y +E + + G +W R + L+ Y++RI A N G S P S Sbjct: 21321 SINTYIIERRDKTGLRWVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPSS 21380 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 T+ P P N V ++T S+T+ W +P +GGS IT YI+E + WT Sbjct: 21381 PFYKACDTIFQPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVETCLPEEDEWTI 21440 Query: 1915 IVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 + + G + I N+ E E ISA N GV P Sbjct: 21441 VTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEP 21478 Score = 229 bits (561), Expect = 5e-58 Identities = 229/896 (25%), Positives = 368/896 (41%), Gaps = 57/896 (6%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249 +E P I+ L + I V A L V I T +V W K + I + + + S Sbjct: 22573 LEAPDIDLDADLRKMITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFT 22632 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +L+I D +YT L +A T + V V++ P D +R+K + ++ Sbjct: 22633 --SLVIENVNRFDSGKYTLTLENASGTKSAFISVRVLDTP----DMPANFRVKEITKNSV 22686 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK-KVENTDAG-IYKLRL--E 1363 + ++ P + + S I++K + T+ + + + K+E + G IY R+ E Sbjct: 22687 TLTWEP-PLLDGGAKIKSYIVEKRESTRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAE 22745 Query: 1364 NNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 N G A+ + I + P PPGK +++++ S+++ W++PE+ G S I YY VE Q Sbjct: 22746 NEHGIGLPAETPEPLKISEVPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQ 22805 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 D +W + T + NL Y FR AVN+ SD V K+ I+ Sbjct: 22806 AKDQDKWSLCAQVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPV-VAKDLAIE 22864 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXX 1536 PTV L + + D+++ G P+P +TW +DG LK A + Sbjct: 22865 -PTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLT 22923 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTA 1594 Y + N G+ E + + I +KP I + + W Sbjct: 22924 IKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSAESITLSWDPPT 22983 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 G I K N + T T +++ LK ++ I A N G S Sbjct: 22984 YTGGCQISNYIVQKRDTTTTNWVVVSATVARTT--LKVGNLKTGAEYQFRIFAENRYGKS 23041 Query: 1655 ----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 S V + K P G + ++ES+ +EW P+ DGG + Y +E+ E ++ Sbjct: 23042 YGIDSDPVLAQYPFKEPGPPGTPFVSAFNKESMVVEWHKPVSDGGSAILGYHLERKEKNS 23101 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSX 1769 W K+ + Y L E EY FRV A+N VG + + SE + + D P Sbjct: 23102 ILWTKINKILIQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSEGCIARDPCDPPG- 23160 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RI 1826 + SV + W P E +GGS + Y VE + EG+ K + Sbjct: 23161 ---TPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVEKRDLPEGRWMKASFANILETEFTV 23217 Query: 1827 QKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 L + Y FR+ ARN G+ S P S +T + PP+ + V+ S+ +T+ Sbjct: 23218 TGLIEDCKYDFRVIARNGAGSVSRPSESTGSVTAKDEVEPPT----YEVASEYSQILTVN 23273 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII----FRI- 1940 + S S + I + KG V V S I+N K ++ RI Sbjct: 23274 AGDTFSLEASVLGKPIPAMQWFKGD-----VEVENSARAE-IKNTDFKAVLVVKDAIRID 23327 Query: 1941 SAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 + T+ +S S+SV + P PP PL + V + SW P DGG+ + Sbjct: 23328 GGQYTLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVTNEKCSLSWLPPRHDGGSSIS 23387 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 Y I R+ ++ W V D F + L + + Y+ R+ A N+ G+ EPLES Sbjct: 23388 YYVIQKRETSRLAWTVVSG-DCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEPLES 23442 Score = 229 bits (560), Expect = 6e-58 Identities = 182/697 (26%), Positives = 296/697 (42%), Gaps = 34/697 (4%) Query: 1282 EVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPS 1337 EV E P +D + ++ G + L + P P W I +I++ H Sbjct: 18269 EVHEHPEIDLDASLRKGLSVRAGCPIRLFATIRGRPAPKVTWKRIGVDNVIRR-GHVD-Q 18326 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 ID+ + L I + D+G Y L L N G V + V +LD P P G + +I +S Sbjct: 18327 IDTMTF-LVIPESSREDSGKYSLTLSNPSGEKAVFVRVKVLDTPGPVGGLDATDITKTSC 18385 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAV 1456 + W PEN G S I+ Y+VE +E+D W + N + KT I NL Y FR AV Sbjct: 18386 QLAWLPPENDGGSPILNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAV 18445 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK---V 1513 N+ I ++ + Y P + + IT L + G + V Sbjct: 18446 NKYGIGLPQDSPKSYLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIV 18505 Query: 1514 TWYRDGK-KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-----EVETSCVVGI 1567 + +DG+ + K + ++ A N G E E V Sbjct: 18506 EYQQDGQPEDKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKE 18565 Query: 1568 Q-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 Q P I +S D+ + G + +V A++ G P P W + + + I Sbjct: 18566 QLMAPKIIVS--DVVTA-RAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPT 18622 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 TS++ +K++ R S Y++ A N+ + + + + D P P+GP+ + E+ ++ T+ Sbjct: 18623 TSLLMVKDVTRKDSGYYSLSAENSTAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLA 18682 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQN 1745 W P +DGG +T Y +EK + W+ +T C + KL EY FRV A+N Sbjct: 18683 WDTPAEDGGSNITNYIVEKCDVTRGDWVTAVSC---TKTSCRVGKLTCGKEYGFRVRAEN 18739 Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G SE + SE ++ + D PS + E V ++W +GGS + Y +E Sbjct: 18740 RFGISEPIYSEKMIARHPFDPPS-EPLNCCVNKVSKEFVVLSWEKPVNDGGSALTGYFIE 18798 Query: 1806 IKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 K+ W L Y FR+ A N+ G P D IT Sbjct: 18799 RKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFRVSAVNKAGQGKPSKQTDFITARSP 18858 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 + PP +P + + T SV+L W+ P+ +GGS + Y +EF +K W ++ + +V Sbjct: 18859 VDPPGKPE---IIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNSQNV 18915 Query: 1923 --HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 E+ + ++E + FRI A+ + VS+P+E V Sbjct: 18916 PKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDV 18952 Score = 229 bits (559), Expect = 8e-58 Identities = 243/1084 (22%), Positives = 435/1084 (40%), Gaps = 68/1084 (6%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHM 690 PP F +K P A+ V G + LEC++ I+W +K + I+ D N+ + ++ + Sbjct: 6466 PPEFVQKLPAAKVVKMGEPLQLECKVTGTAPLRISW-YKNDAILSDGGNLRMTFDNSV-- 6522 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 +VL+I+ G YT A N G S L IK EPP + + +G+ Sbjct: 6523 --AVLEISTSSFDDNGVYTCEAQNDAGTKSCSTALTIK----EPPSFYKLPTPVEGLKGK 6576 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 L+ ++ G+ ITW K+ K +K S+G + ++ IL + D G Y KA Sbjct: 6577 DASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEGCSATLHILG-LEASDAGEYECKA 6635 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N+ G + + EP P F+ + T + L+ V + +++W Sbjct: 6636 TNNVGSDLCQGSVKLREP-------PAFVKKLSNTTAISGEEVVLLTTVKGSQPMTVSWV 6688 Query: 868 RNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ + I+ E F+ + L + DS +G Y C N AG + A +T+ +E Sbjct: 6689 QDKDHILRDGENRKITFENNEVTLKVFKADSTT-AGKYTCQLKNDAGVAECTANLTV-LE 6746 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 V S G+ LEC S T + KW+ + E+S +I Sbjct: 6747 PAAIVDKTD-SISVTAGEAAALECTVSGTPELKPKWFKDGVELSSGKKYKITFSKMISSL 6805 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQDFE-VKEKDVAILE 1037 D G +K++ S ++ T+ P F RKL+D + + K + + Sbjct: 6806 KLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDKIVPPLFSRKLKDTQSIVGKSMELDC 6865 Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 S + W + I N Y+ + L + + D G Y C + + Sbjct: 6866 KASGSAPLTISWFHNEVEIMSGPN-YEITFTENTCTLKVPTLKLSDSGTYKCKAVNSAGA 6924 Query: 1098 AEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153 AE + VV+ PP +T Q + G TF + + ++WF+ EI + Sbjct: 6925 AETSASLVVKEPPSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCE 6984 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209 + + G L++++ D AGEY+C++ G C L V+E + +F +L + Sbjct: 6985 IALRGDTAILELHNIDKSHAGEYTCQIINDAGKENCPVNLFVKEAA-HFVKKLKNLSVEM 7043 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268 + + V W+K I + K+ + + L ++ +YTC Sbjct: 7044 GKSLILECTYAGSPKILVKWHKDGQEIYSSYKYNITTTESSCILECLNSDKEAAGKYTCE 7103 Query: 1269 VLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 V DA + V ++E PP ++ + G V L P+ W Sbjct: 7104 VSNDAGHDICEAAVSILE-PPFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGK 7162 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 ++ K A L + KV +D G Y + EN+ G A ++T+ D +PP P Sbjct: 7163 VRSSPTCKMEFFKGIACLKLAKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFP 7222 Query: 1388 ----NILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDT-TEWISVKNITKTQTSIQ 1441 +I++I+ + E G+S + + ++ + + + + +E+ + +I Sbjct: 7223 KKITSIMQIEGQPVQF---ECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNSAVLNIA 7279 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 + S + A N V S + ++E + P +K L + + +EL Sbjct: 7280 KGEMRHSGEYTCVATNSV----GSASCRAKLTLQEPRYP-PVFDKKLVPVDVSVGDTVEL 7334 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 C G KVTW +D K ++T + EN Y C A ND G Sbjct: 7335 ECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKADSGRYSCHASNDVG 7394 Query: 1558 EVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 + S V ++++ P + G + + G P V WYK+G ++ Sbjct: 7395 KDSCSTEVSVKERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFT 7454 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 Y++T K +V+ IK+ + S S Y +A+N AGT+S EV++ + + P + + Sbjct: 7455 SDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKATNEAGTASFEVSVHITAQKVPPSFDLPL 7514 Query: 1676 REIS 1679 + ++ Sbjct: 7515 KPVT 7518 Score = 227 bits (554), Expect = 3e-57 Identities = 191/758 (25%), Positives = 317/758 (41%), Gaps = 37/758 (4%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 +TW K S ++ T + + TL I+ T +D Y V+ + + VE++ Sbjct: 22896 ITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIIIL 22955 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSAS 1344 K RI S ++ + + P +++ I++K T + + S + + Sbjct: 22956 E-KPGPPTGPVRIDEVSAESITLSWDP-PTYTGGCQISNYIVQKRDTTTTNWVVVSATVA 23013 Query: 1345 LTIKKVENTDAGI-YKLRL--ENNCGHA-----DVEMNVTILDKPSPPGKPNILEIDSSS 1396 T KV N G Y+ R+ EN G + D + +P PPG P + + S Sbjct: 23014 RTTLKVGNLKTGAEYQFRIFAENRYGKSYGIDSDPVLAQYPFKEPGPPGTPFVSAFNKES 23073 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--LKTNSSYRFRAY 1454 + + W +P + G S I+ Y +E +E ++ W + I T + L+ Y FR Y Sbjct: 23074 MVVEWHKPVSDGGSAILGYHLERKEKNSILWTKINKILIQDTRYKTSPLEEGIEYEFRVY 23133 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT---CIFGGVPQP 1511 A N V I S+T+E I P P+ I T + + T G + Sbjct: 23134 AENIVGIGKCSKTSE--GCIARDPCDPPGTPVPV--IVTRHSVKLRWTPPEYDGGSLVTG 23189 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE--TSCVVGI 1567 V RD + + KA++ N Y + IA N G V + + Sbjct: 23190 YVVEKRDLPEGRWMKASFANILETEFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTGSV 23249 Query: 1568 QQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 K + ++ ++ GD + + A + G P P + W+K ++EN I Sbjct: 23250 TAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEI 23309 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 + +V+ +K+ R +YT+ SN AG+ SV ++V D+P PEGP+ + ++ E Sbjct: 23310 KNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVTNE 23369 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 ++ W PP DGG ++ Y I+K E W V+ D + + KL + EY+FRV Sbjct: 23370 KCSLSWLPPRHDGGSSISYYVIQKRETSRLAWTVVSG-DCGATMFKVTKLLKGNEYIFRV 23428 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 +A N G E LES ++++ P I +S+ + W E +GG+ I+ Sbjct: 23429 MAVNKYGVGEPLESRAVIMRNPFVAPG-PPQDLEITNISRDSMTVCWTRPESDGGNEIVG 23487 Query: 1802 YKVEIK-QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 Y VE + + G +W R+ L+ + Y+FR+ A N G P Sbjct: 23488 YIVEKRDRAGIRWTKCNKRRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPSQPTVYYK 23547 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVT 1917 P QP N + ++T SVT+ W+ P +GG I Y++E + W T Sbjct: 23548 ACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGYVVEISKADEEEWITCTPP 23607 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 G + + I + E E RI A N +GV P Q Sbjct: 23608 TGLNDTKFSITKLTEHQEYKVRICALNKLGVGEPVPIQ 23645 Score = 221 bits (541), Expect = 1e-55 Identities = 193/772 (25%), Positives = 332/772 (43%), Gaps = 54/772 (6%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 +VTW K ++ T + +++ + I+ T +D +Y L + ++ V+ Sbjct: 25060 EVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFGVKSAEISVIV 25119 Query: 1286 F----PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 PP + E ++L D + + +N+ +++K T + Sbjct: 25120 LDKPGPPGAIKVEEI----SADFISLSWDPPIY---DGGCQINNYVVEKRDTTTTAWQIV 25172 Query: 1342 SASL---TIKKVENTDAGIYKLRL--ENNCGHAD-VEMNVTILDKP-SPPGKPNILEID- 1393 SA++ +IK T Y+ R+ EN G + ++ + P +PPG P L++ Sbjct: 25173 SATVARTSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIVAQYPFTPPGPPTSLQVSH 25232 Query: 1394 --SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449 S + + W+ P + G S I+ Y +E ++ + W + IT+TQ + L+ Y Sbjct: 25233 ATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNRGLITETQFKVTGLEEGLQY 25292 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGV 1508 ++R YA N I ++ + + +P + + NIT T + GG Sbjct: 25293 QYRVYAENIAGIGPCTKACD---PVSARDPCAPPSQPRVMNITRTSVSLSWTKPEFDGGA 25349 Query: 1509 PQPKVTWY-------RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---- 1557 KVT Y DG+ LK T ++ IA N G Sbjct: 25350 ---KVTGYIVERSELPDGRWLK-CNFTNLQETYFDVTGLIEDQRYDFRIIAKNAAGLFSE 25405 Query: 1558 EVETSCVVGIQQK---PVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 E++ V ++ P ITI ++ ++Q K G+ + A I G P P + W K+G + Sbjct: 25406 PSESTGPVTVKDDVDPPRITIEDK-LRQLVVIKAGEILRIDAEISGRPIPVISWAKDGKE 25464 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 +E + I++ ++ + +++ R S +Y + N AGT S+ V KV D+P GP Sbjct: 25465 IEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNCKVLDRPGPSSGP 25524 Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732 + + ++ E T+ W PP ++GG E+ Y +EK E W V D T + KL Sbjct: 25525 LDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVY-ADMKATTCKVTKLL 25583 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 + EY+FRV N G EALES+P VP+ + +E++ I W Sbjct: 25584 KGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTVPA-APTDVEVTSVTSEAMTICWERPI 25642 Query: 1793 KNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSL 1849 +GGS I Y +E +++ G +W R++ L Y++R++A N G S Sbjct: 25643 SDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSA 25702 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 P L PS P + +ST SVTL W +P +GGSP+T Y++E++ Sbjct: 25703 PSVPCPLTKAEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEYRNTND 25762 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 WT V S E + + E +F + + N +G S P+ ++ K Sbjct: 25763 DDWTVGVNNTKST-EFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDPQVAK 25813 Score = 220 bits (538), Expect = 3e-55 Identities = 213/890 (23%), Positives = 373/890 (41%), Gaps = 68/890 (7%) Query: 1276 TTKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 T+++++E ++ PKI + + ++ G+ + P P W + K + K Sbjct: 15569 TSEVRIEDIKTAPKIFMDISADELLCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKK 15628 Query: 1333 ---HTKPSIDSKSAS------LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 H P +DS+ S +T+ + +G Y + +N G V + V +LD P Sbjct: 15629 DRLHILP-VDSQVESTDTTSVVTVPVSLRSHSGRYTITAKNKSGQKHVNVRVNVLDVPGA 15687 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQ 1441 P + + ++ +++ + W P+N G I Y +E + ++ W +V N T + + Sbjct: 15688 PKELKVTDVTRTTMRLIWKLPDNDGGERIKSYFIEKKAVNGKAW-TVANATCASMAFVVS 15746 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIE 1500 NL Y FR A N + +ETTE V I P +K N+ T+ + Sbjct: 15747 NLLEGQDYFFRVRAENRLGFGPFTETTE--PVRARDPIYPPDPPTKVKINLVTK--NTVT 15802 Query: 1501 LTCI----FGGVPQ-----PKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXY 1548 LT + GG P +++W G + +T K + + Sbjct: 15803 LTWVPPKNDGGAPVKHYIIERLSWDTSGPQKETWKQCNKRDVEETTFIIEDLKEGGEYEF 15862 Query: 1549 KCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVI 1605 + A N+ G S G I K + D+++ + G + + A I+G P P ++ Sbjct: 15863 RVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGAEGFDVNIVARIQGCPFPSLV 15922 Query: 1606 WYKNGNKLENDK---EYN-----ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 W+K +DK +Y+ + + EK S+ I++ KR S+ YT+ A+N+ GT++ Sbjct: 15923 WHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLF-IQQSKRDDSAMYTLTATNSLGTATKS 15981 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 + L + +P P GP+ + E+ E + + W PP DDGG ++T Y +EK E + W+ V+ Sbjct: 15982 IKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGGSKITNYVVEKREENRKTWVHVS 16041 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 ++ + Y +Q+L E EY FRV+AQN G L SEP + P Sbjct: 16042 SDPKECQ-YIVQRLTEGHEYEFRVMAQNKYGVGPPLYSEPEKARNLFTPPG--PPTPKVT 16098 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTT 1834 +V + W P +GGS I Y VE KQEG ++W+ + + L Sbjct: 16099 DCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGL 16158 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESN 1892 Y+FR+ A N G P D I + PP + V E ++ S Sbjct: 16159 YRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSG 16218 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 +P + + + ++ + ++ ++ I++ + + I+ ++A+N G Sbjct: 16219 KPAPEIIWNRDDAELPKEAAVETTSISSAL---VIKSCLRQHQGIYTLTAKNAGG----- 16270 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 E + + + VP P P + ++ +W +PE DGG+ + Y I R+ + Sbjct: 16271 ERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNYIIEKREADRRG 16330 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEE 2072 W V V ++ L + Y RI A N IG+ E+ P V+ + E Sbjct: 16331 WTSV-TYTVTRHNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAP--VVIKDPLSVPER 16387 Query: 2073 PGEQTEVXXXXXXXXXXXXXWLR-EHNMDADIRSYARGSLLRRDEYFFRI 2121 P E EV W +++ +DI SY L + F RI Sbjct: 16388 P-EDVEV--TAITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRI 16434 Score = 220 bits (537), Expect = 4e-55 Identities = 213/847 (25%), Positives = 345/847 (40%), Gaps = 54/847 (6%) Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK------IVDYEREYRIK 1300 DV++ T II E + E+ ++ ++ V K +D Sbjct: 15843 DVEETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGA 15902 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIV------NSKI-IKKCKHTKPSIDSKSASLTIKKVENT 1353 G DV ++ Q P P+ W + K+ ++ KH + + SL I++ + Sbjct: 15903 EGFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKRD 15962 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412 D+ +Y L N+ G A + ++IL +P P P I E+ + I + W+ P + G S I Sbjct: 15963 DSAMYTLTATNSLGTATKSIKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGGSKI 16022 Query: 1413 IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDA--SETTE 1469 YVVE +E + W+ V + K Q +Q L Y FR A N+ + SE + Sbjct: 16023 TNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPPLYSEPEK 16082 Query: 1470 YYKVIKETKIQSPTVEKPLKN-ITTE--PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 + +P V K+ + E P + + I G + K + +K+K K Sbjct: 16083 ARNLFTPPGPPTPKVTDCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWEKVKD-K 16141 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKHK 1585 + + + GE E + V+ ++ + + + D K K Sbjct: 16142 EIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEK 16201 Query: 1586 V----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 + G + A + G P PE+IW N + E KE + T +S + IK R H Sbjct: 16202 IVVHAGGVIRILAYVSGKPAPEIIW--NRDDAELPKEAAVETTSISSALVIKSCLRQHQG 16259 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 YT+ A N G V ++V D P P ++ +S + W P DDGG +T Y Sbjct: 16260 IYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYSPEDDGGSAITNY 16319 Query: 1702 AIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759 IEK E D W V V R +Q L + Y FR+ A+N +G E + P+V Sbjct: 16320 IIEKREADRRGWTSVTYTVTR--HNAVVQGLIDGKGYFFRIAAENIIGMGPFTETAAPVV 16377 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXX 1818 IK L VP I N+S+ + W + +GGS I Y +E++ G+ + Sbjct: 16378 IKDPLSVPE-RPEDVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRLIGQDNFSRIAK 16436 Query: 1819 XXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF--- 1872 R L ++Y+FR+ A N+IG P S +T K PP+ F Sbjct: 16437 EDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKPVTCKKEFEPPNLDLEFRDK 16496 Query: 1873 -VVSESTSRSVTLKWT-EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 VV + + ++T +PE P + + ++ + T + IE Sbjct: 16497 LVVRVGETCIIQSRYTGKPE-----PTIKWFKNDEELQANEEIALTTAKNRL-SLTIEKA 16550 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 K + + EN++G + + P PP P+ + N ++ SW P Sbjct: 16551 KRDHSGKYMVVLENSIGT-----RKGICTVNVVDRPQPPEGPVIFDEIYRNYMVISWNPP 16605 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 DGGA + Y + RD + +WM V + T + L E Y+IRI A+N G+S Sbjct: 16606 LDDGGAAISNYIVEKRDTNRDLWMPVTESCTRT-SCKVPKLIEGREYIIRICAQNIHGIS 16664 Query: 2051 EPLESDE 2057 +PL S E Sbjct: 16665 DPLLSAE 16671 Score = 215 bits (526), Expect = 8e-54 Identities = 246/1060 (23%), Positives = 413/1060 (38%), Gaps = 72/1060 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F K P +G D L C L +I W +++ E C Sbjct: 6560 PPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKYKFVSEG-----C 6614 Query: 693 SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L I ++ G Y A N G +K++ EPP ++ L + GE Sbjct: 6615 SATLHILGLEASDAGEYECKATNNVGSDLCQGSVKLR----EPPAFVKKLSNTTAISGEE 6670 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI------LKPKKVKDE--GVY 803 V+L V G+ T++W ++ + DG+ IT LK K G Y Sbjct: 6671 VVLLTTVKGSQPMTVSWVQDKDHILR-----DGENRKITFENNEVTLKVFKADSTTAGKY 6725 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 T + +N G+AE +A +TV EP +++ I+V L V+ P Sbjct: 6726 TCQLKNDAGVAECTANLTV-------LEPAAIVDKTDSISVTAGEAAALECTVSGTPELK 6778 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W+++ +S + F L + + + D+G+Y N G S ++T+ Sbjct: 6779 PKWFKDGVELSSGKKYKITFSKMISSLKLLSTERS-DTGEYTFSIKNEVGSDSCAMQLTV 6837 Query: 924 DVEKVTFVKHLQKSYETEE--GKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEG 979 ++K+ +K +T+ GK++ L+C+ S + ++ W+HN+ EI + EI Sbjct: 6838 -LDKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTE 6896 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035 D G KC + ETS LVVKE P F+ Q E Sbjct: 6897 NTCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEP-PSFVTTPQPVEALPGTTVT 6955 Query: 1036 LEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-ILRD 1093 + T + W R + I ++ + RG L + N GEY+C I+ D Sbjct: 6956 FTATVQGSTPMKLKWFRGSKEIVSGRS-CEIALRGDTAILELHNIDKSHAGEYTCQIIND 7014 Query: 1094 ---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149 E+C + V E + +L+N V G E LV+W KDG EI S Sbjct: 7015 AGKENCPVNLFVKEAA-HFVKKLKNLSVEMGKSLILECTYAGSPKILVKWHKDGQEIYSS 7073 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEF 1205 +T L+ + D + AG+Y+CEV N C A +++ EP F + E Sbjct: 7074 YKYNITTTESSCILECLNSDKEAAGKYTCEVSNDAGHDICEAAVSILEPP--FFIESLEP 7131 Query: 1206 ILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 + V A L +I + ++W+K + + + L + K + D Sbjct: 7132 MEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEFFKGIACLKLAKVAKSDIG 7191 Query: 1265 EYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 EYTC + A S+ L V+ V+ PP G V Sbjct: 7192 EYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVS 7251 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W+ + + ++ S D SA L I K E +G Y N+ G A +T+ + Sbjct: 7252 WLKDGEALRSDSEYTMSFDDNSAVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQEP 7311 Query: 1381 PSPPG-KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-Q 1437 PP ++ +D S + E TG+ I + + ++++I T + + T Sbjct: 7312 RYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPH 7371 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 +I S R+ +A N D+ S +TE +KE KI +KP I + Sbjct: 7372 LTILKADKADSGRYSCHASN--DVGKDSCSTEVS--VKERKIPPSFTKKPSTTIEDIEGK 7427 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXX-XXXXXXXXXXXYKCIAF 1553 +++ G V WY+DG+++ T+ T+++ Y C A Sbjct: 7428 VVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKAT 7487 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N+ G V I + V + +K G+ ++ + G PP ++ W K+ + Sbjct: 7488 NEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRE 7547 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 L + IT + T+ + + + ++ S Y +A+N AG Sbjct: 7548 LSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKATNEAG 7587 Score = 215 bits (525), Expect = 1e-53 Identities = 237/987 (24%), Positives = 404/987 (40%), Gaps = 71/987 (7%) Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNS- 1183 E + + D RW K N +T ++G++ + ++ + AG +S +S Sbjct: 28608 ERKASSDDEEARWLKCNYTTITENFFTVTSLVEGEQYEFRVIA--RNGAGVHSMPSASSG 28665 Query: 1184 --KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTE 1240 C T + ++ L + E I + A +D L + + V W K ++ E Sbjct: 28666 LITCKDEYTPPKAELDSKL-VGETISIRAGSDLVLDAAVGGKPEPKVFWAKGDKELDPGE 28724 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYR 1298 K++L + II+ C +D Y + +A T+ + V+V++ P Sbjct: 28725 KYSLTYTSTRAMAIIKSCDRNDTGRYILTVKNASGIKTSAVNVKVLDTPGPPAG---TIT 28781 Query: 1299 IKRGSDVTLLVDYQAFPQPNDE----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 I R +D V ++ + + +IV + + + K+ S K+ + Sbjct: 28782 ISRVTDEKCTVSWKIPLEDGGDHVSHYIVERRETSRLNWVIMETECKTLSCVSTKLIKNN 28841 Query: 1355 AGIYKLRLENNCGHA-DVEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGN 1409 I+++R N G +E I P+PPG P+I I + I W +PEN G Sbjct: 28842 EYIFRVRGVNKYGPGVPLESEPVIARNAYTVPTPPGTPDITAIGKEHVIIEWFKPENDGG 28901 Query: 1410 STIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 S I Y+V+ +E + W V I T+ I L S Y+FR AVN S S+ Sbjct: 28902 SEIKNYLVDKREKSSVRWTRVNKTYTIYDTRLKITGLLEGSDYQFRVSAVNAAGTSAPSD 28961 Query: 1467 TTEYYKVIKETKIQSP--------TVEKPLKNITTEPNED--IELT-CIFGGVPQPKVTW 1515 ++Y T +P T + + T P D ++T I + + W Sbjct: 28962 ASQYAHCKDPTYTPAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGTEQW 29021 Query: 1516 YRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 YR +K L + + T F++ G +ET+ + + P I Sbjct: 29022 YRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMGTGEFSE-GSMETAPSERV-EIPDIE 29079 Query: 1575 ISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 + +E K + G+ + + G P P + W K G L++ + + TT+ TS+I ++ Sbjct: 29080 LPDELKKTVCIRAGNTLRLNVTVSGRPAPVITWRKTGIDLQS-RGFIDTTENSTSLI-VE 29137 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 ++ R + KYTIEA N +G ++ + +K+YD P P G V +++ ++ESV I W P D Sbjct: 29138 KVHRYDAGKYTIEAENPSGKKTITILVKIYDTPG-PCGAVNVKDYTKESVVITWDVPTID 29196 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753 GG + Y IEK E + K + Y I L E +Y FRV+ +N G E Sbjct: 29197 GGAHINNYIIEKREASMKSY-KTVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPC 29255 Query: 1754 ES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-K 1811 E+ EP+++ VP +V + W +GGS + + +E + G Sbjct: 29256 ETPEPVLVCEVPSVPQDLYLIDTT----KSTVILGWEKPLHDGGSRLSGFVIEACKTGTD 29311 Query: 1812 KWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--- 1866 +W + I L+ N Y FRI A N G S P +TI + P Sbjct: 29312 RWMNVAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKID 29371 Query: 1867 --SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P+ +V+ + + L P +P+ ++ +K K + + Sbjct: 29372 LTGIPQK-IVNVPAGKPIVL--NIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTK 29428 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 + D + ++ +N G + + + L+K P P P++I V + V Sbjct: 29429 LTVRETTIDDTGDYTLNVKNVSGTATEV-IRVIILDK----PGVPVGPMKIEEVDATSVT 29483 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 SW P+ DGGA + GY + RD + WM V + V F L E Y+ R+ A Sbjct: 29484 CSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSE-SVTRPVFKFTRLVEGTEYVFRVAAT 29542 Query: 2045 NEIGLSEPLESD----EPFKVIPGEGS 2067 N G+ L+S+ + K +PG S Sbjct: 29543 NRFGIGGFLQSEVVECKSVKTVPGAPS 29569 Score = 215 bits (524), Expect = 1e-53 Identities = 242/1128 (21%), Positives = 442/1128 (39%), Gaps = 74/1128 (6%) Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD--ILEGIPPTFSKKPKAQYVDEGSDIL 652 T L++ + DH E T + ++ +PP F ++ + V+ GS Sbjct: 4574 TYTLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVIPRVPPVFRQRIQNLEVNVGSSAK 4633 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 EC + P W G E+ E + H + S L+I + G YT A Sbjct: 4634 FECEIEEAPGVTFKWFKSGTELRHSEKCRII---SRH-HTSSLEIFSPAVADSGEYTCKA 4689 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 NR G S K+ E PP+ + SM + G+ + G+ + W K+N Sbjct: 4690 SNRHGSDSCS--AKLTVTELFPPEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDN 4747 Query: 773 KPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 + SD + + + IL + D+G Y KA NS G A + V Sbjct: 4748 IAISLDDHYKESSDKNRYFLEILNLQH-SDQGTYLCKASNSVGTATCCTELRV------- 4799 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 + P F+ F+ TV ++L +V + SI W R+ + + + F+ E I Sbjct: 4800 VDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFE-EKIA 4858 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 + D+G Y C A+N AG SS + VT+ E FVK L+ ++G + L Sbjct: 4859 CLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQ-EPPVFVKRLEPKILWKQGMSSRLS 4917 Query: 950 C--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---- 1003 C + S + W+ N K ++ + +I + D G C V + Sbjct: 4918 CTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEIIDLSESDSGNYTCEVMNEAGC 4977 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNK 1062 + S+ + VKE P F ++L+ EV + A LE E+ ++ W +D + K Sbjct: 4978 ESCSSQVTVKEP-PAFKKELRLVEVVKGCTAHLECEMTGTAPFEITWFKDKNPVS-SDTK 5035 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVN 1119 Y+ + L I+ D G+Y C + ++ T V ++ PP + +++N Sbjct: 5036 YNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTKAVAKLKDPPSFVKKVENTTAV 5095 Query: 1120 KGNKATFEIELTKGDA--LVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEY 1176 G+ + + KG A V+WFKD ++ + +I T + L I + ++ G+Y Sbjct: 5096 LGSAVKLQGTI-KGSAPITVQWFKDTEIVRDDDPNITTTFENNIAVLAISNVAINHGGKY 5154 Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYK 1231 +C E G KC A +TV+EP+ F + P I V A A L ++ L V W+K Sbjct: 5155 TCQAENEAGKQKCEATVTVQEPA-RF-VEKPPCISVTAGDSATLECKVSGSPDLKVKWFK 5212 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPK 1289 + K+ + L I D EY + + K + V+E PP Sbjct: 5213 DGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSNRVGKEQCSCSINVLE-PPV 5271 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 + + G+ V L + +W K + ++ S+SL + Sbjct: 5272 FSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNSSSLELHA 5331 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 ++ + + Y ++ N+ G + + + P ++++D + + + N Sbjct: 5332 LKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPK-----FVMKLDLTKLVL------NGSL 5380 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-----A 1464 +T+ V EI + W + + Q T+S R + D D + Sbjct: 5381 ATLECKVAGSPEI-SIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQAS 5439 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 S+ T + P KP ++ D+ L G +++ ++D K+++ Sbjct: 5440 SDAGSDRCSCLVTVKEPPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRN 5499 Query: 1525 AK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNE 1578 + + ++ Y+C N+ G+ +V +++ P V + N Sbjct: 5500 DRRHIISLTKDVAALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMKEPPSFVQKMDNT 5559 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 ++ V + V++G P + W K+ ++++ + I+ + +T+VI I ++ Sbjct: 5560 NVLLAKDVS----LQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYISSVQLK 5615 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 H KYT A N AG+ L V + + E + R+ T+E Sbjct: 5616 HGGKYTCHAQNEAGSQKCTAVLTVKEPANITEQAKSVSVTVRDPATLE 5663 Score = 213 bits (520), Expect = 4e-53 Identities = 264/1195 (22%), Positives = 453/1195 (37%), Gaps = 91/1195 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +EK + GS VQF + G P I WF+ T Sbjct: 5832 PSIIEKPESQDVIPGSKVQFNVLLSGTPPLTINWFKDT---------------------- 5869 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 +EV +G V KN SS+ EL P SD G + A + Sbjct: 5870 -KEV---SSGIDCSVQKNDT---SSSIELFFAKP-SDSG-QYVCEVSNDVGSDSCQATLF 5920 Query: 630 EGIPPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 PP F++KP K V ++ EC++ PE D W G +I P + + + Sbjct: 5921 VKEPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYKMTFVDSL 5980 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L+I + G Y A N G S + L++K EPP +++PL + V Sbjct: 5981 ----ARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVK----EPPVLVKPLSPLEVVN 6032 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK--DEGVYTL 805 G + V G +TW K++K +K+ L SI L +K D G Y Sbjct: 6033 GSNAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQC 6092 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 N G + + ++++EP P F+ R + + ++ V +P SI Sbjct: 6093 IVANEVGSCSSQSTLSIKEP-------PSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQ 6145 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W ++ I +I + F+ N+ + V I SG Y C A N AG+ + T+ V Sbjct: 6146 WQKDESWILEDPSIQRTFEN-NVATLTIPVCESIHSGKYTCQAMNEAGQEKCFS--TLVV 6202 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983 ++ + + G V EC+ S T + KW + KE+ + Sbjct: 6203 QEPPQIIEKPEVINVTAGDPVSFECKVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQ 6262 Query: 984 XXXXXXXXXDVGVIKCIVKDQETS-----TMLVVKETIP-EFIRKLQDFE-VKEKDVAIL 1036 D G V + ++ T+ V+++ IP FI+ L + E + K+V I Sbjct: 6263 LKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPPSFIKPLMEMEEIIGKNVQIG 6322 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 S V WE+DG + + + + L I D G Y+C L +++ Sbjct: 6323 CKISGSLPITVEWEKDGTKLSGRTKHKILQDENSV-SLDIECLEKADTGTYTCKLANKAG 6381 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156 + E + E + N V K +F+ V+WFKD +E+ + Sbjct: 6382 SCECSGTLRVKESQAVIPNTTVRF--KGSFK---GTPPFTVKWFKDDTELICGPSCFTGL 6436 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 +G L ++ + +G YSC++ N E P F +LP +V L Sbjct: 6437 EGLSCFLDLFAVGISHSGTYSCQISND-------AEPP--EFVQKLPAAKVVKMGEPLQL 6487 Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 ++ L ++WYK +++ D + D L I + DD YTC + Sbjct: 6488 ECKVTGTAPLRISWYKNDAILSDGGNLRMTFDNSVAVLEISTSSFDDNGVYTCEAQNDAG 6547 Query: 1276 TTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 T + ++ PP +G D +L + + W + K +K+ + Sbjct: 6548 TKSCSTALTIKEPPSFYKLPTPVEGLKGKDASLNCELKGSAPFEITWFKDKKQLKESRKY 6607 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 K + SA+L I +E +DAG Y+ + NN G + +V + + P+ K + S Sbjct: 6608 KFVSEGCSATLHILGLEASDAGEYECKATNNVGSDLCQGSVKLREPPAFVKKLSNTTAIS 6667 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + + T+ + + + E + + +++ K +S+ + Y Sbjct: 6668 GEEVVLLTTVKGSQPMTVSWVQDKDHILRDGENRKI-TFENNEVTLKVFKADSTTAGK-Y 6725 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 + + +E T V++ I T +I+ E L C G P+ K Sbjct: 6726 TCQLKNDAGVAECTANLTVLEPAAIVDKT-----DSISVTAGEAAALECTVSGTPELKPK 6780 Query: 1515 WYRDGKKL---KTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 W++DG +L K K T+ Y N+ G + + + K Sbjct: 6781 WFKDGVELSSGKKYKITFSKMISSLKLLSTERSDTGEYTFSIKNEVGSDSCAMQLTVLDK 6840 Query: 1571 PVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 V + + +K VG + G P + W+ N ++ + Y IT E T Sbjct: 6841 IVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTENTCT 6900 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 +++ LK S S Y +A N+AG + +L V + PS P + + +VT Sbjct: 6901 LKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPSFVTTPQPVEALPGTTVT 6955 Score = 211 bits (516), Expect = 1e-52 Identities = 213/896 (23%), Positives = 354/896 (39%), Gaps = 52/896 (5%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVK 1249 V+ P I +L + +++ A + EI + V +W K IE +F + S + Sbjct: 25419 VDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLT 25478 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 TLI+R D +Y L + T L V K++D R D+T L Sbjct: 25479 STTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNC-----KVLD--RPGPSSGPLDITGLT 25531 Query: 1310 DYQAF-----PQPN-----DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + PQ N +IV + + T D K+ + + K+ + I++ Sbjct: 25532 AEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVYADMKATTCKVTKLLKGNEYIFR 25591 Query: 1360 LRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +R N G +D + P+ P + + S ++ ICW+ P + G S+I Sbjct: 25592 VRGVNKYGTGEALESDPAKAMDPFTVPAAPTDVEVTSVTSEAMTICWERPISDGGSSISG 25651 Query: 1415 YVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 YV+E +E W+ V K + + NL+ Y +R +A N +S S K Sbjct: 25652 YVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVFAENAAGLSAPSVPCPLTK 25711 Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPK-VTWYRDGKKLK-TAKATY 1529 + SP + K + + T GG P + YR+ T Sbjct: 25712 AEDPLFLPSPPAKPKIIDSTKTSVTLSWNKPLFDGGSPVTGYMVEYRNTNDDDWTVGVNN 25771 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ------QKPVITISNEDIKQK 1583 + + N G E S Q +PV ISNE K Sbjct: 25772 TKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDPQVAKEREDEPVFLISNEMRKTL 25831 Query: 1584 H-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + + +G P P V+W K L +I T + + + I++ R S K Sbjct: 25832 VVKDGSSFTLRVPFKGKPVPHVMWNKPDVDLR--VRASIDTTDTCTSVTIEQATRDDSGK 25889 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 YT+ N AGT+++ +++KV D P P + ++E+++ S TI W P ++GG + Y Sbjct: 25890 YTVTLQNVAGTATLTLSVKVLDSPG-PPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYL 25948 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 ++ E W ++++ + TY + L E Y FRV +N G LE++ T Sbjct: 25949 VDLREATKMGWSRISNSCPRL-TYKVTNLQEGGVYYFRVTGENEYGVGVPLETKE---GT 26004 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXX 1821 + + ESV + W E +GGS I +Y VE ++G +KW Sbjct: 26005 KITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCGSTKS 26064 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-QPRNFVVSES-TS 1879 + L N Y FR+ A N G S P + + L P ++F + + Sbjct: 26065 THFVVDGLRENAEYYFRVRAENHAGLSDPKDMVLPVLVKDQLEAPEINMKDFQHNTAYVK 26124 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 LK P + P + + + +K S+ + E++ D + Sbjct: 26125 AGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYLRESV-ASDAGRYD 26183 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 I+A N+ G + + V L++ P P P+E+ + + V W P +DGG+P+ Sbjct: 26184 ITASNSNGTT-KSFVNVVVLDR----PGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPIT 26238 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 Y + R+ T W+EV V I L+ Y RI A N G+SE ++S Sbjct: 26239 NYIVLKRETTTANWIEVSSA-VARCTIKIMKLNTGVEYQFRIKAENRFGISEHIDS 26293 Score = 211 bits (515), Expect = 2e-52 Identities = 174/697 (24%), Positives = 296/697 (42%), Gaps = 34/697 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438 P+PP P I + SI++ W P G S + Y+VE E T +W K +T TQ Sbjct: 28975 PAPPSVPRITDTTKHSISMTWTRPMYDGGSDVTGYIVEILEEGTEQWYRATQKTLTSTQY 29034 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEP 1495 ++ L +N Y FR AVN + + SE + + +++ P +E P K + Sbjct: 29035 TVTGLASNKKYSFRVAAVNAMGTGEFSEGS--METAPSERVEIPDIELPDELKKTVCIRA 29092 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAF 1553 + L G P P +TW + G L++ T EN Y A Sbjct: 29093 GNTLRLNVTVSGRPAPVITWRKTGIDLQSRGFIDTTENSTSLIVEKVHRYDAGKYTIEAE 29152 Query: 1554 NDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N G+ + +V I P N K V W V + G I K Sbjct: 29153 NPSGKKTITILVKIYDTPGPCGAVNVKDYTKESVVITWDVPTIDGGAHINNYIIEKREAS 29212 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKP 1669 +++ K +TT+ K ++ RI L+ + + N G T + V + PS P Sbjct: 29213 MKSYK--TVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPCETPEPVLVCEVPSVP 29270 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 + ++ + ++ +V + W+ PL DGG L+ + IE + +RW+ VA V V + I Sbjct: 29271 QDLYLI-DTTKSTVILGWEKPLHDGGSRLSGFVIEACKTGTDRWMNVAHVKSSVLQHTIV 29329 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYIT 1787 L EN +Y+FR+ A+N G SE + P+ I+ ++P ++ I Sbjct: 29330 SLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKIDLTGIPQKIVNVPAGKPIV 29389 Query: 1788 WFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 K +P+ + V++K + + K +++ +I+ T + + +N Sbjct: 29390 LNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETTIDDTGDYTLNVKNV 29449 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 GT+ T ++ I L P P + E + SVT W P+ +GG+ ++ YI+E Sbjct: 29450 SGTA---TEVIRVII---LDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVE 29503 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 + W ++V SV + + E E +FR++A N G+ +S+ V + Sbjct: 29504 QRDAHRPGW---MSVSESVTRPVFKFTRLVEGTEYVFRVAATNRFGIGGFLQSEVVECKS 29560 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 TVP P+ P EI V + + +W PE +GG+ + GY I ++ W+ + K V Sbjct: 29561 VKTVPGAPSTP-EILDVSHDGMTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPV 29619 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ L E Y R+ A N G +P + +P Sbjct: 29620 TMTRYRATGLIEGLEYEYRVTAINSRGTGKPSANSKP 29656 Score = 210 bits (512), Expect = 4e-52 Identities = 175/676 (25%), Positives = 306/676 (45%), Gaps = 39/676 (5%) Query: 632 IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 IPP+F+KKP D EG + +E R+ + W G EI + V +S + + Sbjct: 7409 IPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAV 7468 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 C I + GTY A N G AS + + I T +K PP PLK + V +GE Sbjct: 7469 LC----IKKSQLSDSGTYVCKATNEAGTASFEVSVHI-TAQKVPPSFDLPLKPVTVNEGE 7523 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808 ++ LS V G+P I W K+ + + + L+ +V D G Y KA Sbjct: 7524 TLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKAT 7583 Query: 809 NSEGI---AETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 N G A A P E + + FI + + + EKGT +A+V +P+P++ Sbjct: 7584 NEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIPNV 7643 Query: 865 TWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + ++ I+ G+ ++ I V ++ DSG Y+CVASN G+ + + Sbjct: 7644 KWMKGKWRQMTHGGRISIEQKGQEAKMEIKEV-TKSDSGQYRCVASNKHGEIECSTDLNV 7702 Query: 924 DVEKVTFVKHLQ------KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-DHREII 976 D +K T V+ ++ K +E K + + + V K Y + G+ D R ++ Sbjct: 7703 DEKKETTVEMVKLKKTPSKQKSPKEEKDIDI-VELLRNVDPKEYEKYARMYGITDFRGLL 7761 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV-----VKETIPEFI-RKLQD--FEV 1028 Q G I +++ + ++ +++T P + R + D V Sbjct: 7762 QAIEFLKKEKELESGRPEGEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTV 7821 Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 K++ V E++IN + W + + + +KYD + G L I++ DEG Y Sbjct: 7822 KKEAVFECEIKINYPEITLSWYKGTQKLD-SGDKYDIKIVGDRHILKIKDCQTRDEGNYR 7880 Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 + +A++TV+E E+ +Q+ +G T +L+ + +WF++G ++ Sbjct: 7881 IVCGPHISSAKLTVLEA--EVEKPMQDVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEP 7938 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 + + QKL I D +D GEY+C+ N + TA L +E I+FT R+ + I+V Sbjct: 7939 HSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRI-QNIVV 7997 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 + A E+ + VTWYK ++++ K+T S+ ++ +IIR + D+ Y+ Sbjct: 7998 REHQSATFECEVSFDNAVVTWYKDTWELKESPKYTFRSEGRRHFMIIRNVSSADEGVYSV 8057 Query: 1269 VLL-----DAKSTTKL 1279 ++ +AKST +L Sbjct: 8058 IVRLEPRGEAKSTAEL 8073 Score = 210 bits (512), Expect = 4e-52 Identities = 219/907 (24%), Positives = 378/907 (41%), Gaps = 66/907 (7%) Query: 1188 ILTVEEPSI-NFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLI 1245 I+T +E I + + + A + L+ I + VTWYK + D + Sbjct: 27582 IMTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEV-DKMLVDIT 27640 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSD 1304 + + +L IR + + YT ++ TTK+ V V V+ P + + Sbjct: 27641 TVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQDTPGPPEGPLRFTNISAEK 27700 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYKLR 1361 TL + + P+ + +++ +I+K + ++ S + SK + + + Y+ R Sbjct: 27701 ATL---WWSPPENDGCAAISNYVIEKRETSRISWALVTSKCEACSFNATKLIKGNEYQFR 27757 Query: 1362 LE--NNCGHAD-VEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 + N G +E + I P PG P+ + +SI +CW P + G + I Sbjct: 27758 VSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTPDCTHVTGNSITLCWTRPRHDGGNEIKQ 27817 Query: 1415 YVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 Y++E +E + W+ V + IT+ + + NL + Y FR A N I AS + + Sbjct: 27818 YILERREKKSLRWVKVSAKRPITELRHRVTNLTEGNEYEFRVMAENGAGIGPASGISRLF 27877 Query: 1472 KVIKETKIQS-PTVEKPLKN----IT---TEPNEDIELTCIFGGVPQPKVT---WYRDGK 1520 K + T S PT+ K + + +T T+P D L I + K + W+R Sbjct: 27878 KCREPTSAPSAPTLVKVIDSTKTSVTLAWTKPVFDGGLEIIGYIIEMCKASLEEWHRVNN 27937 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVIT 1574 + T T+ ++ A N G+ E S I Q P I Sbjct: 27938 Q--TCIQTHYR-----VTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEID 27990 Query: 1575 ISNEDIKQKHKVGDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I + D KQ H V + V I G P P W K L +I T + S + I Sbjct: 27991 I-DADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDL--GVMVDINTTDTFSTLTI 28047 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 + R + KYT+ N +G ++ +T+KV D P P GP+ ++++R ++T+ W P + Sbjct: 28048 ENCTRYDAGKYTLSLENNSGRKTITLTVKVLDTPGPP-GPLSFKDVTRGALTLMWDAPSN 28106 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DGG + Y +EK E W +V++ R + + L+ Y FRV A+N G E Sbjct: 28107 DGGARVHHYIVEKREASRLSWQEVSERCTRQI--LRVINLDIGVAYFFRVTAENQYGKGE 28164 Query: 1752 ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 E +EPI+ A + P+ + + + W E +GGS I Y VE +++G Sbjct: 28165 PYEMTEPII---ATEEPASPKRLDVIDT-TSTTASLVWMKPEHDGGSRITGYIVETRKKG 28220 Query: 1811 K-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W ++ L NT Y+FR+ A+N+ G S P + + I + P+ Sbjct: 28221 SANWVFGGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTAD 28280 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIE 1928 + + + + + G P + + +K K ++ + + ++ Sbjct: 28281 LSSIDKQLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVK 28340 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988 + K D + ++ EN G T + V P+PPT P+EI V S + +WG Sbjct: 28341 DAKRGDSGKYYLTLENAAGSKTFTVTVIV-----IGRPTPPTGPVEISGVSSESCVLTWG 28395 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P DGG + Y + R+ T W V V + L++ Y R+ A N+ G Sbjct: 28396 EPSDDGGTDITNYIVEKRESGSTTWQVVNS-SVKRTTIKVTHLTKYMEYTFRVSAENKFG 28454 Query: 2049 LSEPLES 2055 +S+ +ES Sbjct: 28455 VSKSIES 28461 Score = 209 bits (511), Expect = 6e-52 Identities = 130/439 (29%), Positives = 207/439 (47%), Gaps = 15/439 (3%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSV-----EVTLK-VYDKPSKPEGPVIMREISRESVT 1684 R+K L K+ + A N AG ++ +K D P P P + +++++ S Sbjct: 13658 RVKGLPTRKKYKFRVLAENLAGPGKPSKETDQILIKDPIDPPWAPGKPTV-KDVAKTSAF 13716 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 ++W P DGG ++ Y +E + + W++VAD +E + ++ L E EY FRV A Sbjct: 13717 LQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSLEHF-LKGLMEKQEYSFRVRAV 13775 Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G SE E S+P++ K L+ PS N S + W E++GGSPI +Y Sbjct: 13776 NVAGESEPSEPSDPVLCKERLNPPSPPRWLLVVSSSRN-SAELKWTAPERDGGSPITNYI 13834 Query: 1804 VEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 VE + +K W+ + L+ + Y FR+ A N +G S +D + Sbjct: 13835 VEKRDVRRKGWQAVDTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELEDSVLAKD 13894 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 T P P N ++E + V LKW P+++GG P+ Y+IE K G W K G Sbjct: 13895 TFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKSGKTSGP 13954 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 + + ++ E E+ F++SAEN GV P+E + + + T P P L I + Sbjct: 13955 DCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIEDPTGPPSPPQELHITEAARD 14014 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD---LSENHTYM 2038 + +W PE +GG+P++GY+I + + WM V V LK+ D + Y Sbjct: 14015 HICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNSRPVKELKYRAGDEEGIVPEKEYT 14074 Query: 2039 IRIYARNEIGLSEPLESDE 2057 R+ A N +G SEP + E Sbjct: 14075 FRVRAVNSVGASEPSDISE 14093 Score = 209 bits (511), Expect = 6e-52 Identities = 171/704 (24%), Positives = 289/704 (41%), Gaps = 38/704 (5%) Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 M I P PP P I + ++ W P G + Y+VE+++ +W+ Sbjct: 20301 MTKDIAYPPGPPSNPRITDTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTT 20360 Query: 1433 ITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-K 1489 I T+ + NL++ Y FR A+N + + SE + +++ ++ ++ L K Sbjct: 20361 IPLRITEFVVSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRK 20420 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX 1547 + + I + G P P+V WY++ LK T E+ Sbjct: 20421 TLVVKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGK 20480 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y N G+ V + P + + +I KH + +W + + G I Sbjct: 20481 YVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREIT-KHSITLQWEIPLIDGGSKIKNYI 20539 Query: 1606 WYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LK 1661 K + K Y+ ITT + +I +L+ + + + A N G T ++ Sbjct: 20540 IEK---REATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIR 20596 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 PS P+ +I+ ++S+++ T+ W P DGG +T Y IE D+++W V + Sbjct: 20597 ASQAPSAPDD-LIVTDVSKDTATLAWTKPKHDGGSRITGYVIEAQLKDSDQWAHVTTIK- 20654 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI-- 1779 Y +L EN EY+FR+ A N G SE ES P+VIK P + Sbjct: 20655 -ALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVA 20713 Query: 1780 ---DNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTT 1834 DN V I + P++ +K E ++ + ++ I ++ Sbjct: 20714 KAGDNLKVEIPVLGRPR----PLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDG 20769 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Q+ + +N +GT T + + + PP+ P + E + V + W PE++GG Sbjct: 20770 GQYSMTGKNILGT---VTENITVQVHDIPGPPTGP--IKLDEVSCDYVLISWEAPENDGG 20824 Query: 1895 SPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 PI NYI+E + G SW ++ TV + + + E FR+ A+N GV Sbjct: 20825 VPINNYIVEMRETTGTSWMELAATVIRTTFKAA--RLTTGIEYQFRVKAQNRYGVGPYIT 20882 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S V VP P P +I + + SW P DGG+P+LGY+I ++ +W Sbjct: 20883 SGPVVAAYPFDVPGQPGIP-QIVAFTKDAMTISWNEPSSDGGSPILGYHIERKEKNSILW 20941 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + K V F L + Y R+ A N GLS+ + E Sbjct: 20942 QRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKASKPSE 20985 Score = 209 bits (511), Expect = 6e-52 Identities = 200/800 (25%), Positives = 337/800 (42%), Gaps = 52/800 (6%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVK 1249 +E P IN V A ++ + + + + L V+ K V++ T +F Sbjct: 26106 LEAPEINMKDFQHNTAYVKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTD 26165 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 + +R+ D Y ++ TTK + V V++ P V I S Sbjct: 26166 SLIIYLRESVASDAGRYDITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDS---- 26221 Query: 1308 LVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIK-KVENTDAGI---YKLR 1361 V + P D I N ++K+ T I+ SA K+ + G+ ++++ Sbjct: 26222 -VSLKWLPPAYDGGSPITNYIVLKRETTTANWIEVSSAVARCTIKIMKLNTGVEYQFRIK 26280 Query: 1362 LENNCG---HADVEMNVTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 EN G H D + L P P +P + + SI + W EP + G S + Y Sbjct: 26281 AENRFGISEHIDSQTVTVSLPYTLPVAPSQPWVSAVTKESIVVNWKEPSSDGGSHVFGYH 26340 Query: 1417 VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 ++ ++ ++ W V I T + N+ Y F+ A N I S++++ V+ Sbjct: 26341 LQMKDRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSD--PVL 26398 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYE 1530 + P + + + GG K+T Y +DG K + +KA Sbjct: 26399 AIDACEPPNSVRVTDITKNSISLAWQKPSYDGG---SKITGYLIEMKDGPKGRWSKANLT 26455 Query: 1531 NRXXXXXXXXXXXXXXXY--KCIAFNDHGEVET-SCVVG------IQQKPVITISNEDIK 1581 N Y + +A N G V S +VG P + + E + Sbjct: 26456 NVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLD 26515 Query: 1582 Q-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 K+K G + I P P + WYK+G +LE+ + +I+ + + I ++E R ++ Sbjct: 26516 VVKYKAGATVQLKIGIVAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNT 26575 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 Y ++ N+ G++ V + V DKP P G + ++I+ +++TI W PP D+GG +T Sbjct: 26576 GTYELKIKNSLGSAYAAVRVLVQDKPGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760 Y +EK E W +++ +D + +L + EY+FRV N G + LES P++ Sbjct: 26636 YIVEKRETSRIMWSIISEKLQDC-IVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRPVIA 26694 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KWKXXXX 1818 + + PS I ++ + W +GGS I Y +E K+E K +W Sbjct: 26695 QNSFVHPS-QPSKPQVTMITRSTMTVVWERPSLDGGSDIDGYYLE-KREKKSLQWFKVIK 26752 Query: 1819 XXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI--TIGKTLTPPSQPRNFVV 1874 R + L+ YQ+R+ A N+ G PY SD I + PPS+P V Sbjct: 26753 DPIRDTRQKVHNLTEGNEYQYRVCAINKAGAG-PY-SDVSIFYKAYDPIDPPSEPTKLRV 26810 Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEK 1933 +ST S+TL W +P +GGS IT+Y+IE + W I + G E + ++K Sbjct: 26811 VDSTKTSITLGWVKPVYDGGSEITSYVIEQRIADETEWVTISSKGEVRTTEFVVSHLKPG 26870 Query: 1934 DEIIFRISAENTVGVSLPTE 1953 +R+SA N VG E Sbjct: 26871 VYYYYRVSAVNCVGTGRSIE 26890 Score = 209 bits (511), Expect = 6e-52 Identities = 172/622 (27%), Positives = 278/622 (44%), Gaps = 34/622 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT- 1436 DKP PG+ +I+ I SI I W PE+ G I+ Y +E+++ + W K +K Sbjct: 30062 DKPGQPGEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDR 30121 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 Q +I L + Y FR +A NE +S T K K + ++P +++ +K+ TT+ Sbjct: 30122 QFTIGGLMEATEYEFRVFAENETGLSRPRRTAMGIKT-KLSVGEAPCLKEDIKDTTTKLG 30180 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIA 1552 E LTC G P P++ WYR GK+L + K + + R Y C A Sbjct: 30181 ESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRA 30240 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG--DEWLVTAVIEGIPPPEVIWYKNG 1610 N+ GE+ETS + +Q P +K+K+ G + V G P P+++W+ Sbjct: 30241 VNEAGEIETSGKLLLQAAPQFH-PGFPLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGK 30299 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 L + I E + + I+ ++R +++ +Y ++ SN GT + +++ DKP P Sbjct: 30300 KPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLP 30359 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE-PDNNRWIKVADVDRDVETYCI 1728 EGPV++ + + SV I WKPP DDGG +T Y +EK E + +W V+ T + Sbjct: 30360 EGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGT-TCRV 30418 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 L E+ Y FRV AQN G SE+LE ++IK+ + P + +S ++ Sbjct: 30419 PNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPG-VPQRPFVSSVTKDSCVVS 30477 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGK--KW--KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 W P +GG+ I +Y +E K+E K KW + L Y+FR+ N Sbjct: 30478 WKPPTSDGGAKIKNYFLE-KREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCEN 30536 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK----WTEPESNGGSPITN 1899 IG ++ + I K+ T P F E V K + P+ Sbjct: 30537 -IGGESDWSEISEPVIPKSDTALRAP--FFKDELRDMCVKYKANATFVTKVVGHPKPVVK 30593 Query: 1900 YIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 + K + + K+ G + I N E D ++I A N +G S S Sbjct: 30594 WYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLG------SISTS 30647 Query: 1959 LEKHATVPSPPTAPLEIRMVGS 1980 + VP+ PL ++ +G+ Sbjct: 30648 MNLDVEVPAKIYLPLHLQGMGA 30669 Score = 206 bits (503), Expect = 5e-51 Identities = 233/1055 (22%), Positives = 426/1055 (40%), Gaps = 78/1055 (7%) Query: 660 IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 I E DI W +G+ + + E + L + NV+ Q G + A+N Sbjct: 11119 ISEDDIPGEWKLRGQVLTRSPTCDIRAEGNKRF----LTLKNVQLDQAGEVSYQALNAVT 11174 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 A +L +K E + PL+ + V + + + + P + W + + V + Sbjct: 11175 SA----MLTVKEIEMD---FTVPLRDVTVHEKKQAKFECTITKDV-PKVLWLRGSDIVTS 11226 Query: 778 ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPP 833 DG H + ++ + +DEG YT+ E + +TS A +TVE + Sbjct: 11227 DQKYDIIDDGKKHML-VINHCEFEDEGEYTI-----EVLGKTSTAKLTVEGMRLK----- 11275 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893 F++ + TVKE T + ++ + VP +TWY+N + PS T+ + DG+ L I Sbjct: 11276 -FVSPISDQTVKEGKTARFELELSHDSVP-VTWYKNETKLHPSRTVLTHVDGKKHILEIK 11333 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953 +V D C A S A +T+ F LQ Y E VIL+C+ S Sbjct: 11334 DVTL-----DDTCQIKAEAKGMSTTANLTVLEGDACFTVKLQ-DYTAVEKDEVILDCELS 11387 Query: 954 HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 V KW+HN+ EI I EG+ D G+ C +TS+ L ++ Sbjct: 11388 KDVPVKWFHNETEIKASKMVAIKVEGKRRILNIKKVEDKDKGLYVCDCGTDKTSSTLNIE 11447 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 + +R + E+ + + A EVEI+ + W+ GE++ P + + + G Sbjct: 11448 ARDIKVVRPMYGVELFDGETARFEVEISEDDVHGQWKLQGEVLSPSPD-VEIIEDGAKHT 11506 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133 L + N V GE S + C+A + V ELP +T L + V + ++A FE E+++ Sbjct: 11507 LTLYNCKVSQSGEVSFQGANAKCSANLKVKELPISFVTPLADVHVYEKDEARFECEISRQ 11566 Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 RW K EI+ + +L +GK+ L + +D +Y E +++ +A L ++ Sbjct: 11567 AKSFRWLKGSQEIKTDDKFELLQEGKRHILVVKAAAYEDEAKYMFEAEDNRTSAKLVIQG 11626 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 + F + + + V A ++E+ E + VTWYK + ++ + D K TL Sbjct: 11627 IRLEFVRPIKD-VTVKERETAEFSIELSHEKVQVTWYKNDVRLHPSKVVHMSEDGKIHTL 11685 Query: 1254 IIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 ++ + DD + + ++A T + + V+E P ++Y +V L+ + Sbjct: 11686 SFKEVSIDDT---SLIKVEALGKTCEAMLTVLEGEPYFTTKLQDYTAVEKDEVVLMCEVS 11742 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 +W + I K+ D K LT+KK E + G Y ++ A + Sbjct: 11743 K-SSAQVKWFKDGNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLN 11801 Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEWIS 1429 + + P + E +++ E + G+ + + + + S Sbjct: 11802 IEERDIKIVRPLYSVEVTETETARFETEISEEDVHGHWKLKGDALHQSPVISFTPKHYFS 11861 Query: 1430 VKNITKTQTSIQNLK-TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 + + + + K Y R VD S A+ ++ +K I + +PL Sbjct: 11862 ITMMKDCEIKEEGTKHMLILYNVRMDMAGAVDFSAANAKSKAQLRVKARVI---GLLRPL 11918 Query: 1489 KNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546 K++T E C + G+P V W+ G KL E Sbjct: 11919 KDVTVTAGETATFDCELSYEGIP---VEWFLGGTKL-------EPSDRVVTRAEGRSHTL 11968 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL---VTAVIE---GIP 1600 + + + GEV+ + + Q +I ++ ++ + D+ + TA +E Sbjct: 11969 TLRDVKLTEAGEVKLTAKDFLTQAQLI-VNEPPVEFTKPLEDQTVEEEATAELECEVSKE 12027 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN--TAGTSSVEV 1658 EV W+++G ++ K+Y++ + I + S YT +A + T+ +VE Sbjct: 12028 KAEVRWFRDGQEIRKTKKYDMVADGCKRKLVIHDCTLDDSKTYTCDAKHFKTSAFLNVEP 12087 Query: 1659 TLKVYDKP------SKPEGPVIMREISRESVTIEW 1687 + KP + E E+SRES + W Sbjct: 12088 PYVEFTKPLHDVEVKEKESARFECEVSRESAKVRW 12122 Score = 206 bits (502), Expect = 7e-51 Identities = 227/940 (24%), Positives = 390/940 (41%), Gaps = 81/940 (8%) Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 Q+ K+ C L+ G + ++ P I L + I+V A + + Sbjct: 23624 QEYKVRICALNKLGVGEPVPIQGSVKPVDKMDAPEIELDSELRKGIVVHAGGSMRINIPF 23683 Query: 1221 PDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK- 1278 + ++ W K + D + D T+ I C +D +YT L ++ T Sbjct: 23684 KGRPIPEINWTKDDGDLPDKAQIDKGPDFTHLTINI--CDRNDAGKYTLTLQNSAGTKSA 23741 Query: 1279 -LKVEVVEFP--PK---IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + V+V++ P P+ + D R Y VTL+ + P + + + II K + Sbjct: 23742 FVSVKVLDTPGAPQNLFVKDITRNY-------VTLVWEP---PLIDGGSKIKNYIIDKRE 23791 Query: 1333 HTKP---SIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDKPSPP 1384 T+ +I +K + + + + T+ GIY R+ EN G + E +V D P Sbjct: 23792 STRQGFTNITTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVKTADPPLSV 23851 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNL 1443 GK + ++ ++ ++ WD+P++ G S I+ Y +E Q + EWI V + KT + ++ L Sbjct: 23852 GKVTLTDVTKTTASLSWDKPDHDGGSRILGYYIEMQPKGSEEWI-VATVCKTCEGTVAGL 23910 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 + Y R A NE SD + K+ I+ P+ + + + ED+++ Sbjct: 23911 SSGQEYLLRVLAYNEKGKSDPRPLASPV-IAKDVTIE-PSFKLTFNTYSVQSGEDLKVEI 23968 Query: 1504 IFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXX---XXXXXXXXXXXYKCIAFNDHGEV 1559 F G P PK+ W +DG+ LK T + + Y A N+ G V Sbjct: 23969 PFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATNNIGTV 24028 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN---D 1616 + I KP I DE T V+ PP Y G ++ N + Sbjct: 24029 TEEVAIIILDKPGPPTGPVKI-------DEVSATYVVISWEPPV---YTGGCQINNYVVE 24078 Query: 1617 KEYNITTKEKT-------SVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV----YD 1664 K TT +T + I+I +LK ++ + A N G S S++ T V + Sbjct: 24079 KRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKSGSIDSTPVVVSYPFT 24138 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 +P+ P P + ++++ +TIEWKPP ++GG + Y +E+ E ++ W K+ + Sbjct: 24139 EPAAPGAPFV-SSVTKDHMTIEWKPPSNNGGSPIIGYHLERKEKNSILWTKLNKLLITDT 24197 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 L E EY +RV A+N G S + + SE +V + D P I Sbjct: 24198 RLRTNGLEEGIEYEYRVFAENIAGISPSSKVSESVVARDPCDPPG----TPEAIVITRNL 24253 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIY 1840 + + W + +GGS I Y +E K+ +G+ K I L Y+FR+ Sbjct: 24254 ITLQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQFTITGLHEEQRYEFRVI 24313 Query: 1841 ARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 ARN G S+P S IT + PS + + ++ G P+ + Sbjct: 24314 ARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGDSFSIDSDIAGKPLPD 24373 Query: 1900 YIIEFKTVKG-KSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 I+ K K S T + + ++ +++ D F +S N G T+ Sbjct: 24374 -IVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSLSNVGG----TKQVP 24428 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + + K P PP PL++ V + W P DGGA + Y I R+ ++ W V Sbjct: 24429 INV-KVLDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSWTVV 24487 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + + + + + L + Y+ R+ A N+ G+ EPLES+ Sbjct: 24488 -EPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESE 24526 Score = 205 bits (500), Expect = 1e-50 Identities = 201/795 (25%), Positives = 321/795 (40%), Gaps = 65/795 (8%) Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 + +Y K G DV +++ + P PN W K I S +L I KV Sbjct: 26910 ISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEYSTTLIIPKV 26969 Query: 1351 ENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 D G Y L +EN G + ++V +LD PS + + + + + W+ P G Sbjct: 26970 TRDDTGKYLLEIENGVGEPKTITVSVKVLDTPSACNRLIVKNVTRGKLTLSWEPPYIDGG 27029 Query: 1410 STIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET- 1467 S I YVVE ++ + V N T + L SY FR A NE + D ET Sbjct: 27030 SPITNYVVEKKDAKMKAFTIVTNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETE 27089 Query: 1468 -----TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 TE IK+ + T + T+P+ D GG + Y KK Sbjct: 27090 QPVRATEMPGAIKDLVLVDST-NTSVSLAWTKPDHD-------GG---SHINEYIIEKKT 27138 Query: 1523 KTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 K + R ++ A N+ G + S + I K + Sbjct: 27139 KDEETWSSGGTCRRCQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEA 27198 Query: 1579 DI------KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 ++ + ++G + +G P P + W K+ L+ ++ E + + + Sbjct: 27199 NLIDYPNGELSVRIGQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIV 27258 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 + ++ ++ KYT+ N + ++ + PS+P GP+ EI +S+ I W P + Sbjct: 27259 RNARKENAGKYTLVLDNKLVKNFFDIKVITLGPPSQPIGPIRFDEIKAQSIIISWDVPQE 27318 Query: 1693 DGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DGG E+T Y++EK E W I + V R T+ I L + EY FRV A+N G S+ Sbjct: 27319 DGGGEITCYSVEKRETSQAAWKIVCSSVVR--TTFKIPNLVKGTEYQFRVRAENKYGVSD 27376 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811 L S P V+ P + ++ + + W +GGSPI Y +E K Sbjct: 27377 PLTS-PDVVAQHQYKPPGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLEKKDRNS 27435 Query: 1812 -KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTS-LPYTSDDKITIGKTLTPPS 1867 W R+ L Y FR+YA+N G S + S K+ I + PP Sbjct: 27436 LLWMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPVSEQSKHKLAI-SPVDPPG 27494 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P N + + T SVTL+W P+ +GGS I Y +E + + + W + + S + + Sbjct: 27495 TP-NCI--DVTRDSVTLQWEPPKRDGGSRIVAYSVERRQGRAR-WLRCNFIDVSECQFTV 27550 Query: 1928 ENIKEKDEIIFRISAENTVG-VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 + D FR+ A N VG VS P++S + K +V +E S + Sbjct: 27551 TGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIMTKDESV----IPQIEFEAEKSLTIKA- 27605 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK------VDVNTL----KFNIRDLSENHT 2036 G L +I+ R V + W + GK VD+ T+ IRD NH Sbjct: 27606 -------GENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDADRNHR 27658 Query: 2037 YMIRIYARNEIGLSE 2051 + + A+N G ++ Sbjct: 27659 GIYTVEAKNSSGTTK 27673 Score = 202 bits (494), Expect = 6e-50 Identities = 180/728 (24%), Positives = 292/728 (40%), Gaps = 36/728 (4%) Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---- 1430 +T PPGKP I+++ SS+++ W P++ G S +I Y VE+ ++ +W+ V Sbjct: 18853 ITARSPVDPPGKPEIIDVTKSSVSLVWSRPKHDGGSKLIGYYVEFLKLKEDKWVRVNSNS 18912 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 +N+ K + + L+ + Y+FR A +++S SE ++ +I E + +KN Sbjct: 18913 QNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIPIIAEHVPPRVEISLEMKN 18972 Query: 1491 -ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXX 1545 I + ++ L G P PKV W +DG LK A K T + + Sbjct: 18973 LIVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKES 19032 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD----EWLVTAVIEGIPP 1601 Y A N G + + + KP S ++ H D W G Sbjct: 19033 GEYTITAENPSGSKSANIKLKVLDKPGPPAS---VRISHVFADRVKLRWEPPLADGGSEI 19089 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 I K N + + + +++L H ++ I A N G VT Sbjct: 19090 TNYIVDKRETSRANWAQVTANINGQITDCSVEKLIEGHEYEFRISAENKYGVGDPIVTSS 19149 Query: 1662 V-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 V +D P E PVI ++R+ +T+ WK P +DG + Y +EK E + W+KV Sbjct: 19150 VMAKNPFDVPGPCEPPVI-TNVTRDHMTVTWKAPANDGKATILGYMVEKRETQDLNWVKV 19208 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 T L E EY FRVIA N G + + V+ P Sbjct: 19209 NRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPVYPPGPPAFPKV 19268 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA---RIQKLSIN 1832 + S+ ++W +GG I+ Y VE K+ + ++W A + L N Sbjct: 19269 VDSTHSSISLSWTKPAYDGGCEILGYLVEFKRADAEEWMKCNVPKNLQATKFNVTGLIDN 19328 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPE 1890 T YQFR+ A N+IG P +K L P + + ++ VT++ P Sbjct: 19329 TEYQFRVSAVNKIGFGEPSEVPEKHLAKDILLAPEAELDADLRKALVLRAGVTMRIYVPL 19388 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 +P + +K + I T +C E+I D + ++ EN+ G Sbjct: 19389 RGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYC-EDINRYDAGKYVLTLENSSG--- 19444 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 T+S ++ + K P PP L ++ + V +W P DGG+P+ Y + R + Sbjct: 19445 -TKSYTI-VVKVLDTPGPP-VNLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEKRLAER 19501 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070 W V T F I +L Y R+ A N G+ E E+ P K G A+ Sbjct: 19502 KAWTCVAPECPKT-SFRITNLEAGQAYCFRVLAENIYGIGEGCETAGPVKASEQPGPVAE 19560 Query: 2071 EEPGEQTE 2078 + E T+ Sbjct: 19561 FKSMEITK 19568 Score = 202 bits (492), Expect = 1e-49 Identities = 234/1090 (21%), Positives = 436/1090 (40%), Gaps = 68/1090 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP FS KP++Q V G+ ++L I W + +E++ + E++ Sbjct: 5269 PPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFREDKEMLTGGTCFIKKETNS---- 5324 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGES 751 S L++ +K Q YT N G+ S L +K EPP+ + L + +V G Sbjct: 5325 SSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVK----EPPKFVMKLDLTKLVLNGSL 5380 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK--VKDEGVYTLKAEN 809 L +V G+P +I W KN + + T S+ L+ V+D G Y +A + Sbjct: 5381 ATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRISSCCVEDSGDYICQASS 5440 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G S ++TV+EP E F+ F+ + + + L V+ + I+ +++ Sbjct: 5441 DAGSDRCSCLVTVKEPPE-------FVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKD 5493 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 ++ I + + L I + D+G Y+C N G++S VT+ E + Sbjct: 5494 SKQIRNDRRHIISLTKDVAALQILKFEPG-DAGKYQCTVGNEVGQTSCDFLVTMK-EPPS 5551 Query: 930 FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 FV+ + + K V L+C + S ++ W + EI +H +I E + Sbjct: 5552 FVQKMDNT-NVLLAKDVSLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQTAVIYIS 5610 Query: 988 XXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042 G C ++ Q+ + +L VKE + + V +D A LE + + Sbjct: 5611 SVQLKHGGKYTCHAQNEAGSQKCTAVLTVKEPA-NITEQAKSVSVTVRDPATLECRYSGT 5669 Query: 1043 ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097 + W +DG E+ +K K I K+ S D GEY+ + ++ SC Sbjct: 5670 KVLKAKWLKDGNELTSGRKYKIQSSDTSSILKILSAEKS--DAGEYTFEVSNDAGRSSCE 5727 Query: 1098 AEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 A VTV++ + P +L+ + KG+ E ++ + V WFK+ EI+ + Sbjct: 5728 AVVTVLDQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKC 5787 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI-LVP 1209 L+I D D+G Y+C + G+ +C+ L V+EP + PE ++P Sbjct: 5788 IFFENAASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPS--IIEKPESQDVIP 5845 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268 + + + L + W+K + ++ + ++ + D +Y C Sbjct: 5846 GSKVQFNVLLSGTPPLTINWFKDTKEVSSGIDCSVQKNDTSSSIELFFAKPSDSGQYVCE 5905 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKI 1327 V D S + V+ PPK + + + S + + P+ + W + Sbjct: 5906 VSNDVGSDSCQATLFVKEPPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGND 5965 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 I K + A L I + D+G+Y N G M++ + + P Sbjct: 5966 ISPSDKYKMTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPL 6025 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKT 1445 + LE+ + S N ++ + + + ++I ++ I KN + +Q Sbjct: 6026 SPLEVVNGS-NAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDA 6084 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 ++ NEV + T IKE P+ + ++N+ T + +E C+ Sbjct: 6085 LDVGEYQCIVANEVGSCSSQSTLS----IKEP----PSFVERIENVVTVLGKMVEFKCVV 6136 Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGEVET 1561 G P + W +D + + + T+EN Y C A N+ G+ + Sbjct: 6137 RGSPPLSIQWQKDESWILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKC 6196 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + +Q+ P I E I GD + G P +V W K+G ++ +++++ Sbjct: 6197 FSTLVVQEPPQIIEKPEVINVT--AGDPVSFECKVSGTPELKVKWSKDGKEVIPSRQHSL 6254 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREI 1678 + S ++++ ++ Y E SN +VTL V ++ PS + + M EI Sbjct: 6255 SYINNVSQLKLQSVQLEDKGTYVFEVSNHISACQCKVTLNVLEQIIPPSFIKPLMEMEEI 6314 Query: 1679 SRESVTIEWK 1688 ++V I K Sbjct: 6315 IGKNVQIGCK 6324 Score = 200 bits (487), Expect = 4e-49 Identities = 207/898 (23%), Positives = 365/898 (40%), Gaps = 57/898 (6%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249 +EE ++ + + + A D + + + +VTW K I ++ + + Sbjct: 26901 LEEADVDLDISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEY 26960 Query: 1250 KRTLIIRKCTEDDQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 TLII K T DD +Y + + T + V+V++ P + + RG +T Sbjct: 26961 STTLIIPKVTRDDTGKYLLEIENGVGEPKTITVSVKVLD-TPSACNRLIVKNVTRGK-LT 27018 Query: 1307 LLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 L + Y P ++V K K T + + + + + + + +++ EN Sbjct: 27019 LSWEPPYIDGGSPITNYVVEKKDAKMKAFTIVTNECANTTYKVDGLSEEISYFFRVSAEN 27078 Query: 1365 NCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 G D E V + P +++ ++S+++ W +P++ G S I Y++E + Sbjct: 27079 EYGVGDPCETEQPVRATEMPGAIKDLVLVDSTNTSVSLAWTKPDHDGGSHINEYIIEKKT 27138 Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-- 1479 D W S + Q + LK S FR +A NE SD S+ +KE I Sbjct: 27139 KDEETWSSGGTCRRCQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPI--TVKEFLIPP 27196 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXX 1535 ++ ++ P ++ +++ + + G P+P + W +D LK ++ EN+ Sbjct: 27197 EANLIDYPNGELSVRIGQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASL 27256 Query: 1536 XXXXXXXXXXXXYKCIAFN----DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y + N + +++ +G +P+ I ++IK + + W Sbjct: 27257 IVRNARKENAGKYTLVLDNKLVKNFFDIKV-ITLGPPSQPIGPIRFDEIKAQSII-ISWD 27314 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNT 1650 V G E+ Y + + + I + +I L + ++ + A N Sbjct: 27315 VPQEDGG---GEITCYSVEKRETSQAAWKIVCSSVVRTTFKIPNLVKGTEYQFRVRAENK 27371 Query: 1651 AGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 G S S +V + KP P G ++ ++ + +T++W P DGG +T Y +EK Sbjct: 27372 YGVSDPLTSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTVQWDAPGFDGGSPITGYHLEKK 27431 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 + ++ W+KV Y + L E EY FRV AQN G S SE K A+ Sbjct: 27432 DRNSLLWMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPV--SEQSKHKLAIS- 27488 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR- 1825 P + +SV + W P +++GGS I+ Y VE +Q +W + Sbjct: 27489 PVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVAYSVERRQGRARWLRCNFIDVSECQF 27548 Query: 1826 -IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 + L+ ++FR+ ARN +GT P + + K + Q + +S+T+ Sbjct: 27549 TVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYIMTKDESVIPQ-----IEFEAEKSLTI 27603 Query: 1885 KWTEPE----SNGGSPITNYIIEFKTVK--GKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 K E S G P+ + +K K K I TV GS I + I+ Sbjct: 27604 KAGENIKLSCSISGRPVPQ-VTWYKDGKEVDKMLVDITTVIGS-SSLFIRDADRNHRGIY 27661 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 + A+N+ G T V + T P PP PL + + W PE DG A + Sbjct: 27662 TVEAKNSSG----TTKVDVLVRVQDT-PGPPEGPLRFTNISAEKATLWWSPPENDGCAAI 27716 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 Y I R+ ++ W V FN L + + Y R+ A N+ G+ +PLESD Sbjct: 27717 SNYVIEKRETSRISWALVTS-KCEACSFNATKLIKGNEYQFRVSAVNKFGVGKPLESD 27773 Score = 199 bits (486), Expect = 6e-49 Identities = 227/1050 (21%), Positives = 434/1050 (41%), Gaps = 72/1050 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K +++ + +G+D++LE + +I+ ++I D +++ D+ Sbjct: 5456 PPEFVKPFESKEIVKGTDVVLEGTVSGSAPFEISCFKDSKQIRNDRRHIISLTKDV---- 5511 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L+I + G Y N G+ S ++ +K EPP ++ + + V + V Sbjct: 5512 AALQILKFEPGDAGKYQCTVGNEVGQTSCDFLVTMK----EPPSFVQKMDNTNVLLAKDV 5567 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L + G+ TI+W K++ +K + + T ++ + ++K G YT A+N Sbjct: 5568 SLQCVLKGSMPMTISWMKDDHEIKESEHVQISFENQT-AVIYISSVQLKHGGKYTCHAQN 5626 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G + +AV+TV+EP + + +TV++ T++ R + V W ++ Sbjct: 5627 EAGSQKCTAVLTVKEPANITEQA-----KSVSVTVRDPATLE--CRYSGTKVLKAKWLKD 5679 Query: 870 -NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--DVE 926 NE+ S + Q+ D +I +++ S D+G+Y SN AG+SS A VT+ + Sbjct: 5680 GNELTSGRKYKIQSSDTSSILKILSAEKS--DAGEYTFEVSNDAGRSSCEAVVTVLDQII 5737 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 K +F + L+++ E+ +G LEC S + ++ W+ KEI + + I Sbjct: 5738 KPSFTRKLKET-ESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIFFENAASL 5796 Query: 985 XXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G CI K+Q + S L VKE P I K + +V V + Sbjct: 5797 EISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEP-PSIIEKPESQDVIPGSKVQFNVLL 5855 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 + + + W +D + + + +K + + D G+Y C + ++ S Sbjct: 5856 SGTPPLTINWFKDTKEVSSGID-CSVQKNDTSSSIELFFAKPSDSGQYVCEVSNDVGSDS 5914 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNK-ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153 C A + V E PP+ + + V K ++ FE ++T + WFKDG++I S+ + Sbjct: 5915 CQATLFVKE-PPKFTRKPEKITVVKPSQLVVFECQITGTPEIDTYWFKDGNDISPSDKYK 5973 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209 +T +L+I D+ D+G Y CE G+ C+ L V+EP + P + V Sbjct: 5974 MTFVDSLARLEIISSDIKDSGVYYCEARNEAGSESCSMDLRVKEPPVLVKPLSP--LEVV 6031 Query: 1210 ANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYT 1267 ++AY + +VTW K I+ + K ++ TL ++KC D EY Sbjct: 6032 NGSNAYFECLVKGTAPFEVTWEKDSKDIKSSLKHVILQKNDSIITLDVQKCDALDVGEYQ 6091 Query: 1268 CVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 C++ + S + ++ PP V+ G V + P + +W + Sbjct: 6092 CIVANEVGSCSSQSTLSIKEPPSFVERIENVVTVLGKMVEFKCVVRGSPPLSIQWQKDES 6151 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 I + + + ++ A+LTI E+ +G Y + N G + + + P K Sbjct: 6152 WILEDPSIQRTFENNVATLTIPVCESIHSGKYTCQAMNEAGQEKCFSTLVVQEPPQIIEK 6211 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKT 1445 P ++ + + + ++ + + + + +E+ + S+ I +Q +Q+++ Sbjct: 6212 PEVINVTAGD-PVSFECKVSGTPELKVKWSKDGKEVIPSRQHSLSYINNVSQLKLQSVQL 6270 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 + N + T + +I P+ KPL + +++++ C Sbjct: 6271 EDKGTYVFEVSNHISACQCKVTLNVLE-----QIIPPSFIKPLMEMEEIIGKNVQIGCKI 6325 Query: 1506 GGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G V W +DG KL K EN Y C N G E Sbjct: 6326 SGSLPITVEWEKDGTKLSGRTKHKILQDENSVSLDIECLEKADTGTYTCKLANKAGSCEC 6385 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 S + +++ + I N ++ K +G PP V W+K+ +L Sbjct: 6386 SGTLRVKESQAV-IPNTTVRFK----------GSFKGTPPFTVKWFKDDTELICGPSCFT 6434 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + + + + + SHS Y+ + SN A Sbjct: 6435 GLEGLSCFLDLFAVGISHSGTYSCQISNDA 6464 Score = 198 bits (484), Expect = 1e-48 Identities = 180/695 (25%), Positives = 290/695 (41%), Gaps = 35/695 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436 +P PPG P +L+ SSI I W++P G S I Y+VE + EW V +T T Sbjct: 21391 QPGPPGNPRVLDTTKSSITIAWNKPVYDGGSDITGYIVETCLPEEDEWTIVTPMAGLTAT 21450 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493 +I NL N Y+ A+N + + + K E ++ P +E K + Sbjct: 21451 SFTITNLTENQEYKINISALNCEGVGEPASVPGSPKA--EDRLLPPEIELDSDLRKVVNI 21508 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRD-GKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCI 1551 + L G P P++ W R+ G+ L A + Y Sbjct: 21509 RACSTLRLFVPVKGRPAPEIRWSREKGEPLDRASIEITPSFTTLLIENVDRFDGGKYMLT 21568 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N G V + P N IK+ K V W VI+G + Y Sbjct: 21569 VENSSGTKTAFINVRVLDTPGAP-QNLTIKEITKDSVSLIW-DPPVIDG--GSRIRHYIV 21624 Query: 1610 GNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEV--TLKVYD 1664 + K Y+I KTS RI +L+ + + I A N G VE +K+ + Sbjct: 21625 EKRESTRKAYSIVNASCPKTSW-RIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISE 21683 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 +P P G V ++E++ SVT+ W+ P DGG +T Y +E ++++W +V V V Sbjct: 21684 RPLPP-GKVTLKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVK--VT 21740 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + L + EY FR+ A N G S+ S P++ K + P+ + + Sbjct: 21741 EAVVVGLTQGEEYSFRISATNEKGISDPRPLSVPVIAKDVVIAPAFKLLFSTFSVLAGDD 21800 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 + I P + ++ K I +E + +++ + + ++ I Sbjct: 21801 LKID-VPYVAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKIT 21859 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 N G + T+D + + PP+ P + E T+ SVTL W PE GG I NYI+ Sbjct: 21860 NSAGEA---TADINVIVLDKPGPPTGP--IKIEEVTADSVTLSWQPPEYEGGCSINNYIV 21914 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 E + +W +IV+ + +K E FRI+AEN G S S+ V + Sbjct: 21915 EKRDTSTTNW-QIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYP 21973 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 +P PP P ++ ++ W P DGG+ +LGY+I ++ +W++ K + Sbjct: 21974 FEIPHPPGIPA-VQSATKESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIP 22032 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 +F I L E Y R+YA N +GLS+ + E Sbjct: 22033 DTRFKIGGLEEGIEYEFRVYAENIVGLSKASKVSE 22067 Score = 198 bits (482), Expect = 2e-48 Identities = 205/933 (21%), Positives = 370/933 (39%), Gaps = 58/933 (6%) Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + W N K +K+ + DT+++ I K K EG YT +A G TS+ +TV Sbjct: 4551 VNWLFNGKCIKSGKEFKCSKEHDTYTLVITKVMK-DHEGEYTCEAVGEAGKTSTSSHLTV 4609 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--IT 880 PP+F R Q + V + K + P + W+++ + SE I Sbjct: 4610 IPRV-----PPVFRQRIQNLEVNVGSSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRII 4664 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYE 939 ++E+ V DSG+Y C ASN G S A++T+ ++ FV S Sbjct: 4665 SRHHTSSLEIFSPAV---ADSGEYTCKASNRHGSDSCSAKLTVTELFPPEFVSK-PDSMT 4720 Query: 940 TEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 GK +C S ++ W+ + IS DH + + D G Sbjct: 4721 LFVGKQAKFQCVISGSEPMNVVWHKDNIAISLDDHYKESSDKNRYFLEILNLQHSDQGTY 4780 Query: 998 KCIVKDQ-ETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDG 1053 C + T+T + P F++ + V + LE +++ +T ++W RDG Sbjct: 4781 LCKASNSVGTATCCTELRVVDKPSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDG 4840 Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108 + + + K FE++ I L I+ + + D G Y+C +E SC++ VTV E PP Sbjct: 4841 KKLHTTMDCKLAFEEK--IACLDIQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQE-PPV 4897 Query: 1109 IITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 + RL+ + + K ++ KG + V WF + + S ++T + L+I Sbjct: 4898 FVKRLEPKILWKQGMSSRLSCTVKGSPELHVTWFLNDKPLNSSEKHKITFKTNQATLEII 4957 Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPEFIL-VPANTDAYLTVEI 1220 D D+G Y+CEV G C++ +TV+E P+ LRL E + A+ + +T Sbjct: 4958 DLSESDSGNYTCEVMNEAGCESCSSQVTVKEPPAFKKELRLVEVVKGCTAHLECEMTGTA 5017 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK 1278 P ++TW+K K+ + K+ ++S L I+ D +Y C + + K TTK Sbjct: 5018 P---FEITWFKDKNPVSSDTKYNIVSKETAAYLEIKTFESADVGDYQCCISNDVGKITTK 5074 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS 1337 V ++ PP V GS V L + +W +++I++ + + Sbjct: 5075 -AVAKLKDPPSFVKKVENTTAVLGSAVKLQGTIKGSAPITVQWFKDTEIVRDDDPNITTT 5133 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 ++ A L I V G Y + EN G E VT+ + KP + + + Sbjct: 5134 FENNIAVLAISNVAINHGGKYTCQAENEAGKQKCEATVTVQEPARFVEKPPCISVTAGDS 5193 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 + + + + ++ + ++ I + + S ++ N Sbjct: 5194 ATLECKVSGSPDLKVKWFKDGKEMAGGRKYKITFKENVAVLKILSAERGDSSEYKVEVSN 5253 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 V S + ++ P ++ P + LT F G + W+R Sbjct: 5254 RVGKEQCSCSINV--------LEPPVFSLKPQSQDVIPGTTVVLTAAFTGTAPFMIKWFR 5305 Query: 1518 DGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 + K++ T + N Y C ND G+V + + +++ P Sbjct: 5306 EDKEMLTGGTCFIKKETNSSSLELHALKPSQSAKYTCQVSNDAGKVSCTAALFVKEPPKF 5365 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 + D+ + G + + G P + WYKN ++ +D +Y + + + +RI Sbjct: 5366 -VMKLDLTKLVLNGSLATLECKVAGSPEISIRWYKNETEIGSDDKYQMAFTDSVATLRIS 5424 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 S Y +AS+ AG+ + V + P Sbjct: 5425 SCCVEDSGDYICQASSDAGSDRCSCLVTVKEPP 5457 Score = 198 bits (482), Expect = 2e-48 Identities = 221/928 (23%), Positives = 374/928 (40%), Gaps = 52/928 (5%) Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 + ++ K+ I + + GE + G+ K L E ++ LR + + + A + L Sbjct: 21459 ENQEYKINISALNCEGVGEPASVPGSPKAEDRLLPPEIELDSDLR--KVVNIRACSTLRL 21516 Query: 1217 TVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 V + ++ W ++K E ++ ++ TL+I D +Y + ++ Sbjct: 21517 FVPVKGRPAPEIRWSREKG--EPLDRASIEITPSFTTLLIENVDRFDGGKYMLTVENSSG 21574 Query: 1276 TTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 T + V V++ P + + K V+L+ D P + + I++K + Sbjct: 21575 TKTAFINVRVLDTPGAPQNLTIKEITK--DSVSLIWDP---PVIDGGSRIRHYIVEKRES 21629 Query: 1334 TKP--SIDSKSASLTIKKVENTDAG---IYKLRLENNCG---HADVEMNVTILDKPSPPG 1385 T+ SI + S T ++ + G +++ EN G + + I ++P PPG Sbjct: 21630 TRKAYSIVNASCPKTSWRIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPPG 21689 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 K + E+ S+S+ + W++P++ G S I Y+VE Q ++ +W V + T+ + L Sbjct: 21690 KVTLKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQ 21749 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 Y FR A NE ISD + VI + + +P + + +D+++ + Sbjct: 21750 GEEYSFRISATNEKGISDPRPLS--VPVIAKDVVIAPAFKLLFSTFSVLAGDDLKIDVPY 21807 Query: 1506 GGVPQPKVTWYRDGKKLK-TAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 P+ V W +DG LK T + E Y N GE Sbjct: 21808 VAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATA 21867 Query: 1562 SCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 V + KP I++ V W G I K N + Sbjct: 21868 DINVIVLDKPGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINNYIVEKRDTSTTNWQIV 21927 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVI 1674 + T T+ + LK ++ I A N G SSV V+ V ++ P P P + Sbjct: 21928 SATVARTTT--KAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAV 21985 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 + ++ES+ + W P DGG ++ Y IE E ++ W+K + I L E Sbjct: 21986 -QSATKESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEG 22044 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 EY FRV A+N VG S+A S+ I+ A D P + SV + W P + + Sbjct: 22045 IEYEFRVYAENIVGLSKA--SKVSEIQVARD-PCDPPGKPEAVIVKRSSVTLRWTPPQFD 22101 Query: 1795 GGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIG-TSLP 1850 GG I Y VE K+ +W + L Y+FR+ ARN G +S+P Sbjct: 22102 GGIKITGYVVEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVP 22161 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--TNYIIEFKTVK 1908 S IT + PP + S++ + + G PI ++I + + Sbjct: 22162 SDSTGAITAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELT 22221 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 + +I + E I+ D + + +N G E + K P P Sbjct: 22222 NTARLEIKNTDFTTTLSVKEAIR-VDGGQYTLLLKNVGG-----EKSVIINVKVLDRPGP 22275 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 P P+ I V S SW TP DGGA + Y + R+ ++ +W V ++ V TL I Sbjct: 22276 PDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLVWTVV-ELKVQTLNLKI 22334 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESD 2056 L + Y+ R+ N+ G+ EPLESD Sbjct: 22335 TKLLPGNEYIFRVIPVNKYGIGEPLESD 22362 Score = 197 bits (480), Expect = 3e-48 Identities = 201/906 (22%), Positives = 374/906 (41%), Gaps = 54/906 (5%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKF 1242 T + T P ++ + + A L + I P T++ WYK +E + Sbjct: 26497 TCVDTYGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIE--WYKDGKELESGAQI 26554 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR 1301 ++ + + + +R+ T + Y + ++ + V V V+ P E +++ Sbjct: 26555 SISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYAAVRVLVQDKPGPPAGEIQFKKIT 26614 Query: 1302 GSDVTLLVDYQAFPQPN--DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 +T++ D A +IV + + + S + +T+ ++ + I++ Sbjct: 26615 ADTMTIMWDPPADEGGAMVTHYIVEKRETSRIMWSIISEKLQDCIVTVPRLIKGNEYIFR 26674 Query: 1360 LRLENNCGHAD-VEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +R N G D +E I PS P KP + I S++ + W+ P G S I Sbjct: 26675 VRGVNKHGVGDPLESRPVIAQNSFVHPSQPSKPQVTMITRSTMTVVWERPSLDGGSDIDG 26734 Query: 1415 YVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 Y +E +E + +W V I T+ + NL + Y++R A+N+ S+ + +YK Sbjct: 26735 YYLEKREKKSLQWFKVIKDPIRDTRQKVHNLTEGNEYQYRVCAINKAGAGPYSDVSIFYK 26794 Query: 1473 VIKETKIQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY------RDGKKLKTA 1525 S PT + + + T GG ++T Y D + T Sbjct: 26795 AYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGG---SEITSYVIEQRIADETEWVTI 26851 Query: 1526 KATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVET-SCVVGIQQKPVITISNEDI--- 1580 + E R Y+ A N G + V +Q K ++ ++ D+ Sbjct: 26852 SSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAKDILEEADVDLDIS 26911 Query: 1581 ---KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 + K G + + ++G P P V W K + D Y I E ++ + I ++ R Sbjct: 26912 MSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNTEYSTTLIIPKVTR 26971 Query: 1638 SHSSKYTIEASNTAG-TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + KY +E N G ++ V++KV D PS +I++ ++R +T+ W+PP DGG Sbjct: 26972 DDTGKYLLEIENGVGEPKTITVSVKVLDTPSAC-NRLIVKNVTRGKLTLSWEPPYIDGGS 27030 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +T Y +EK + + V + + TY + L+E Y FRV A+N G + E+E Sbjct: 27031 PITNYVVEKKDAKMKAFTIVTNECANT-TYKVDGLSEEISYFFRVSAENEYGVGDPCETE 27089 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815 V A ++P N SV + W + +GGS I +Y +E K ++ + W Sbjct: 27090 QPV--RATEMPGAIKDLVLVDS-TNTSVSLAWTKPDHDGGSHINEYIIEKKTKDEETWSS 27146 Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS----QPRN 1871 + +L + FR++A+NE G S ++ IT+ + L PP N Sbjct: 27147 GGTCRRCQCEVTELKELSEVYFRVFAKNEKGRS-DFSQIGPITVKEFLIPPEANLIDYPN 27205 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 +S ++V + P PI ++ + +K + + N + Sbjct: 27206 GELSVRIGQNVNIDL--PYKGKPKPIIQWMKDDVILKESEQVRFRQTENKA-SLIVRNAR 27262 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 +++ + + +N + V + + + L PS P P+ + + ++ SW P+ Sbjct: 27263 KENAGKYTLVLDNKL-VKNFFDIKVITLGP----PSQPIGPIRFDEIKAQSIIISWDVPQ 27317 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DGG + Y++ R+ ++ W V V T F I +L + Y R+ A N+ G+S+ Sbjct: 27318 EDGGGEITCYSVEKRETSQAAWKIVCSSVVRT-TFKIPNLVKGTEYQFRVRAENKYGVSD 27376 Query: 2052 PLESDE 2057 PL S + Sbjct: 27377 PLTSPD 27382 Score = 195 bits (476), Expect = 1e-47 Identities = 152/572 (26%), Positives = 237/572 (41%), Gaps = 27/572 (4%) Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS-----SYRFRAYAVNEVDISDASETTE 1469 Y VE+++ ++ W K +KTQ ++ + Y FR A+N + S TTE Sbjct: 19846 YYVEFKDRNSLMW---KRASKTQLRVKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTE 19902 Query: 1470 YYKVIKETKIQS-PTVEKPLKN----ITTEPNED--IELT-CIFGGVPQPKVTWYRDGKK 1521 + P V +N + T P D +LT + + P TW + Sbjct: 19903 SLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMK-ANH 19961 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 + Y A + E V + +P + ++K Sbjct: 19962 VNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEMK 20021 Query: 1582 Q--KHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 K G ++TA I G PPP +W K G + ++ I++ +S + IK R Sbjct: 20022 DGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPTSSTLSIKYASRK 20081 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 ++ +YTI ASN G +V +KV D P P GP+ +S E T+ W PP +DGG + Sbjct: 20082 NTGEYTITASNPFGIKDEKVKVKVLDVPGPP-GPIEASSVSAEKCTLTWLPPEEDGGCSI 20140 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y +EK E W K+A+ D Y KL + EY+FRV A N G + +S P+ Sbjct: 20141 KSYILEKRETSRLLWTKLAENVMDCR-YVASKLIKGNEYIFRVSAVNQYGTGDVTQSGPV 20199 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXX 1817 + + P + +V I+W +GGS I Y VE K+ G +W Sbjct: 20200 KMVDSFGPPGPPSKPEIDN-VSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRWVRAS 20258 Query: 1818 XXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 R + LS Y+FR+ A N+ G P + PP P N ++ Sbjct: 20259 KKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNPRIT 20318 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 ++T + T W P +GG +T YI+E K W + T+ + E + N++ + Sbjct: 20319 DTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNLQSGGK 20378 Query: 1936 IIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 FR+SA N+ G+ P+E Q V L VP Sbjct: 20379 YHFRVSALNSEGLGEPSEVEQVVELVDREEVP 20410 Score = 194 bits (474), Expect = 2e-47 Identities = 127/459 (27%), Positives = 209/459 (45%), Gaps = 21/459 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I+G P P W K G + + + T++E+T ++ IKE R + Y + N G + Sbjct: 29793 IKGKPLPTCKWTKEGRDISH-RAMIATSEERTELV-IKEAHRDDTGTYDLVLENKCGRKA 29850 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V + +KV +P PEGP+ +I SV + W+PP DDGG ++ Y +E+ E W Sbjct: 29851 VYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGSDIFGYIVERREVPKAAWYT 29910 Query: 1716 VADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXX 1773 V R V+T + K L EN EY F++ A+N G S++L+S E + KT L P Sbjct: 29911 VDS--RVVDTSLVVKGLKENVEYHFKITAENQFGISKSLKSDESVTPKTPLCPPEPPSFP 29968 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLS 1830 + ++ ++W + +GGS + Y VE ++ +KW + L Sbjct: 29969 PEIMDVTKTTIGLSWSRPKDDGGSRVTGYYVERREISTEKWVRHNKTHITTTMYTLTGLI 30028 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 + YQFR+ A+N+IG S P + + P QP F + T S+T+ W PE Sbjct: 30029 PDAEYQFRVVAQNDIGQSEPGPVSESVVCKDPFDKPGQPGEFDIISITKDSITIHWLRPE 30088 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 S+GG I Y IEF+ +W K + I + E E FR+ AEN G+S Sbjct: 30089 SDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQFTIGGLMEATEYEFRVFAENETGLSR 30148 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 P + ++ ++ +V P +I+ + + G + +L I R + + Sbjct: 30149 PRRT-AMGIKTKLSVGEAPCLKEDIKDTTTKL-----------GESGILTCQIIGRPLPE 30196 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 W GK + + K+ + NH+ + + + GL Sbjct: 30197 IKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGL 30235 Score = 194 bits (473), Expect = 2e-47 Identities = 209/878 (23%), Positives = 358/878 (40%), Gaps = 52/878 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284 + W+K ++ E+ L + + +L I K D +Y VL ++ T K V VV Sbjct: 16519 IKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTRKGICTVNVV 16578 Query: 1285 EFP--PK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + P P+ V ++ YR +D N +IV + + + Sbjct: 16579 DRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISN--YIVEKRDTNRDLWMPVTESCT 16636 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSS 1396 S + K+ I ++ +N G +D ++ K P P P + EI + Sbjct: 16637 RTSCKVPKLIEGREYIIRICAQNIHGISDPLLSAETKAKDVFKVPDAPQAPVVKEIYKDT 16696 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRA 1453 I W +P + G I Y+VE +E W + T+ + +L Y FR Sbjct: 16697 ALISWLQPAD-GGKPITNYIVEKKETKANMWARAGKDRIFPNTEYWVPDLLKGCEYEFRV 16755 Query: 1454 YAVNEVDISDASETTE--YYK---VIKETKIQSPTVEKPLKNITT--EPNEDIELTCIFG 1506 A N + I D S +++ Y K VI + ++K +++T +P +D IFG Sbjct: 16756 MAENVIGIGDPSPSSKPIYAKDPIVIPSPPVLPVAIDKTKESVTLSWQPPKDCGRGKIFG 16815 Query: 1507 GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV-- 1564 + + + + ++ + + ++ A N GE E + V Sbjct: 16816 YLLEYQKAGDEEWLQVNQTPDSCPS-TTFKVINLEDGALYRFRVKAVNAAGESEPAYVPE 16874 Query: 1565 -VGIQQK---PVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 V Q + P + + ++ K G + A I+G+P P+V W KN + E Sbjct: 16875 PVRAQDRFEPPELQLDLGMPRELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAE- 16933 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 I T T+ + ++ R+ YT+ N AG+ T+ V DKP P + + ++ Sbjct: 16934 -IETSGTTTKLEMRYCNRTDCGDYTLTVENPAGSKIATCTVLVLDKPG-PVQHLRVSDVR 16991 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 +S + WK P D+GG +T + +EK + + +W+ + + + + L E YMF Sbjct: 16992 SDSAQLSWKDPEDNGGARITNFVVEKKDAASPQWVPICSSSKK-RSMMAKHLIEGTSYMF 17050 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 RV A+N G SE +E+ + P D V++ W ++ GGS I Sbjct: 17051 RVAAENQFGRSEYVETTKAIKAMNPLFPPGPPKDLHHVDADKTEVWLQWNWPDRTGGSDI 17110 Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 + VE ++EG+K W + L TY+FR+ N IG S P T+ + Sbjct: 17111 TGFLVEYQEEGEKDWIVFKTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRPDTTVPVLC 17170 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--TNYIIEFKTVKGKSWTKIV 1916 K L PP + + E P G P+ ++I+ + +K + TKI Sbjct: 17171 QEK-LVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKID 17229 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 T S I + I+ ++ N+ G T S +V + VP+ P P+ I Sbjct: 17230 TDNFST-VLSIADCTRNHTGIYILTVSNSAGSK--TVSLNVTV---LDVPAAPIGPVNIL 17283 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 V + ++ W P+ DGG+P++ Y + R+ K W V +T + I L + Sbjct: 17284 EVTPDSMVIDWRPPKDDGGSPVMNYIVEKRESNKETWGGVSSGSTST-RLKISRLQQGVE 17342 Query: 2037 YMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074 Y++RI A N++G+ LES P H E PG Sbjct: 17343 YVVRIRAENKMGIGAALES------APTVARHQFEAPG 17374 Score = 194 bits (473), Expect = 2e-47 Identities = 183/835 (21%), Positives = 353/835 (42%), Gaps = 52/835 (6%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 ++ I + T DD +YT L + T L V+V++ P E + K + +T Sbjct: 25876 SVTIEQATRDDSGKYTVTLQNVAGTATLTLSVKVLDSPGPPAHIEVKEVTKSSATITWDT 25935 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG 1367 P ++V+ + K ++ I + LT K + G+Y R+ EN G Sbjct: 25936 PDNEGGAPVKNYLVDLREATKMGWSR--ISNSCPRLTYKVTNLQEGGVYYFRVTGENEYG 25993 Query: 1368 HA---DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + + I +KPSPP K + ++ S+++ W +PE+ G S I Y+VE E Sbjct: 25994 VGVPLETKEGTKITEKPSPPPKLGVTDVTKESVSLAWLKPEHDGGSRITNYLVEALEKGQ 26053 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 +WI + T + L+ N+ Y FR A N +SD + V+ + ++++P + Sbjct: 26054 QKWIKCGSTKSTHFVVDGLRENAEYYFRVRAENHAGLSDPKDMV--LPVLVKDQLEAPEI 26111 Query: 1485 E-KPLKNIT--TEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE---NRXXXXX 1537 K ++ T + ++++ G P PKV+ +DG+ LK T + ++ + Sbjct: 26112 NMKDFQHNTAYVKAGSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLIIYL 26171 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAV 1595 Y A N +G ++ V + +P + ++ + V +WL A Sbjct: 26172 RESVASDAGRYDITASNSNGTTKSFVNVVVLDRPGPAVGPVEMCDITEDSVSLKWLPPAY 26231 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654 G P I K N E +++ I+I +L ++ I+A N G S Sbjct: 26232 DGGSPITNYIVLKRETTTANWIE--VSSAVARCTIKIMKLNTGVEYQFRIKAENRFGISE 26289 Query: 1655 ---SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 S VT+ + Y P P P + +++ES+ + WK P DGG + Y ++ + ++ Sbjct: 26290 HIDSQTVTVSLPYTLPVAPSQPWV-SAVTKESIVVNWKEPSSDGGSHVFGYHLQMKDRNS 26348 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSX 1769 W KV + + +N Y F+V A+N G + S+P++ A + P+ Sbjct: 26349 ILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPN- 26407 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--I 1826 I S+ + W +GGS I Y +E+K K +W + + Sbjct: 26408 ---SVRVTDITKNSISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTV 26464 Query: 1827 QKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVT 1883 L+ N +Y+FR+ A+N +G+ S P +T T P P+ ++ T Sbjct: 26465 SGLTQNESYEFRVMAKNAVGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAGAT 26524 Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI---IFRI 1940 ++ P + + K ++ + +++ + CI +++E + + + Sbjct: 26525 VQLKIGIVAKPQPTIEWYKDGKELESGAQ---ISISNTTEFTCI-SVREATRLNTGTYEL 26580 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +N++G + V+ +K P PP ++ + + ++ + W P +GGA + Sbjct: 26581 KIKNSLGSAYAAVRVLVQ-DK----PGPPAGEIQFKKITADTMTIMWDPPADEGGAMVTH 26635 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 Y + R+ ++ MW + + + + L + + Y+ R+ N+ G+ +PLES Sbjct: 26636 YIVEKRETSRIMWSIISE-KLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLES 26689 Score = 192 bits (467), Expect = 1e-46 Identities = 172/688 (25%), Positives = 281/688 (40%), Gaps = 44/688 (6%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P+ +W + ++K + S ++ IK + +D G Y+++ N G Sbjct: 14902 PPPSLKWTKDDGDLEKDRMEVEEAGQDS-TVVIKTTKRSDHGKYQIQAANPSGIKSAWTR 14960 Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434 V ++D P P + + + + W +P++ G S + +++E +E W Sbjct: 14961 VEVMDVPGPVLDLKPVVVTRKLMMLNWSDPDDDGGSDVTGFIIERREPKMHTWRQPIETP 15020 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT----VEKPLKN 1490 ++ I + Y FR A N+ + V + SP E+ + Sbjct: 15021 SSKCEIVGIIEGQEYIFRVVAKNKYGCGPPVDLGPIRAVDPQGPPTSPEKFHYTERTKSS 15080 Query: 1491 ITTE--PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY 1548 +T E P + + I G + + K +++ T + + Sbjct: 15081 VTIEWRPPRNDGGSPIIGYIIEKKRQDQPAFQRVNPELCTVQ---IMTVDNLDELHMYEF 15137 Query: 1549 KCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQ------KHKVGDEWLVTAVIEGIPP 1601 + A N GE E S + + Q + S +K + + + + A + G+P Sbjct: 15138 RAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVTGLPM 15197 Query: 1602 PEVIWYKNGNKLENDKEYNI-TTKEKTSV-----IRIKELKRSHSSKYTIEASNTAGTSS 1655 P++ W K+ +E E + TKE V + I + R YT+ ASN GT S Sbjct: 15198 PKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDKGTYTVTASNRLGTLS 15257 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK-----HEPDN 1710 VT++V D+P+ P V + I ES + W PLD GG ELT Y +E +P+ Sbjct: 15258 HSVTVEVLDRPTPPRN-VAVSSIKAESCNLSWDAPLDIGGSELTNYIVEMKDLNVEDPEK 15316 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 W++V + + Y + L Y FRV A+N G SEA E+E + IK +P Sbjct: 15317 AEWVQVTKSIIE-KRYGVWNLVTGGNYKFRVKAENKYGISEACETEEVEIKDPSALPGPP 15375 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR----- 1825 + +TW P + +GGS I Y +E +++G + R Sbjct: 15376 EKVTIAER-SKTHMLLTWEPPKDSGGSMITGYWLEKREKGTSYWSRVNKILVSKRGMKGW 15434 Query: 1826 ---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + +L Y+FR A N G P + LTPPS P +++ T SV Sbjct: 15435 EYQVTRLFEGVEYEFRAMACNSAGIGPPSAISESAVADDPLTPPSMPAAPEIADKTKHSV 15494 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE---HCIENIKEKDEIIFR 1939 TL WT P +GG PI YIIE + W + V ++H I N+ E + FR Sbjct: 15495 TLAWTPPAKDGGRPIKGYIIEIQDEGTSEWAR-VNDAENLHPSTVFTIPNLPELKKYRFR 15553 Query: 1940 ISAENTVGVSLPT-ESQSVRLEKHATVP 1966 I A N +G S P+ + VR+E T P Sbjct: 15554 IIAVNEIGESEPSPRTSEVRIEDIKTAP 15581 Score = 191 bits (465), Expect = 2e-46 Identities = 164/700 (23%), Positives = 292/700 (41%), Gaps = 42/700 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP P + + + ++ W +P G S ++ Y+VE Q+ EW V I + Sbjct: 17473 PGPPVNPKVKDYSCTYADLVWIKPTKDGGSPVLGYIVECQK-GGAEWEKVNKDDLIKQCA 17531 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 ++ L ++ YRFR AVN + + E E VI + I P +E + +T Sbjct: 17532 YRVKGLTEDTEYRFRVKAVNMIGEGETREIPE--SVIAKDIIIPPEIEMDATCHERVTVR 17589 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXXXXXXXYKC 1550 +I + P P++TW + L+ K T Y Sbjct: 17590 VGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNFPVVQMRIKEATRADHGKYVL 17649 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKN 1609 A N+ GE + V + +P +++K + + +V+ E E+ Y Sbjct: 17650 KAVNEAGEASATITVNVLDRPGHC---QNLKMTYVTKNSCMVSWDAPEDNGGSEITNYIV 17706 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663 + + + + + + + T+ + +L +H + + A N G T + + + Sbjct: 17707 ECREPSIRTWAMISSDCTNRMVKAKLMENHEYLFRVSAENKCGPGPATETKTPILAIDPL 17766 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 KP +PE + +I + V ++W+ P DGG Y +E+ D W K+ + Sbjct: 17767 QKPGEPEN-FHVGDIGKNFVFLKWRKPDYDGGSPNLGYYLERKAKDAEAWEKLHEGVLKE 17825 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NE 1782 + + K EN Y FRV + N G S + + IV+K + P + E Sbjct: 17826 TFFMVDKCVENHIYQFRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGE 17885 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840 SV + + P + + V+ K G + ++ + K + T ++ + Sbjct: 17886 SVRLE--AGLRGKPQPTVTW-VKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVT 17942 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N G+ Y + +T+ L P R+ +S ++ + W PE +GG + +Y Sbjct: 17943 ATNPAGSFTAYAN---VTV---LDIPGPVRDMKISGISTDKCRVAWDPPEDDGGCEVDSY 17996 Query: 1901 IIEFKTVKGKSWTKIVTVGGS-VHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 IIE + W+ T S V +C + + E +E IFR+ AEN +G P ES+ + Sbjct: 17997 IIEKCETRRMVWS---TYSASLVTNYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPII 18053 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + P PP AP E+ +G + + W PE DGG + GY + ++ W+ V K Sbjct: 18054 AKTQYNRPGPPDAP-EVTKIGKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPVTK 18112 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ + + +L NH Y R+ A NE+GL EP ++ P Sbjct: 18113 SPISERRMKVTNLIPNHDYQFRVKAENEVGLGEPSKASRP 18152 Score = 191 bits (465), Expect = 2e-46 Identities = 140/489 (28%), Positives = 223/489 (45%), Gaps = 24/489 (4%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + I+G P PEV+WYK L+ +I T E +++ I E R + KY Sbjct: 20425 KSGASIRIFVPIKGRPAPEVVWYKENVPLKG--RAHIDTTESYTLVVIPECTRYDAGKYV 20482 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + N AG + V ++V D P P + REI++ S+T++W+ PL DGG ++ Y IE Sbjct: 20483 LTLENVAGKKTGFVNVRVVDTPGPPVN-LKPREITKHSITLQWEIPLIDGGSKIKNYIIE 20541 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763 K E + V + +Y I L E EY FRV A+N +G E E+ +PI A Sbjct: 20542 KREATRKAY-SVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIRASQA 20600 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXX 1822 P + ++ + W + +GGS I Y +E + ++ +W Sbjct: 20601 PSAPDDLIVTD----VSKDTATLAWTKPKHDGGSRITGYVIEAQLKDSDQWAHVTTIKAL 20656 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 +L N Y FRI+A N G S P S + +T P R+ +++ Sbjct: 20657 DYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVAKAG 20716 Query: 1883 -TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 LK P P+ + E + +K I S + I IK KD + ++ Sbjct: 20717 DNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILN-INEIKRKDGGQYSMT 20775 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 +N +G T ++++ ++ H +P PPT P+++ V + V+ SW PE DGG P+ Y Sbjct: 20776 GKNILG----TVTENITVQVH-DIPGPPTGPIKLDEVSCDYVLISWEAPENDGGVPINNY 20830 Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-----SEPLESD 2056 + +R+ T T WME+ + T F L+ Y R+ A+N G+ S P+ + Sbjct: 20831 IVEMRETTGTSWMELAATVIRT-TFKAARLTTGIEYQFRVKAQNRYGVGPYITSGPVVAA 20889 Query: 2057 EPFKVIPGE 2065 PF V PG+ Sbjct: 20890 YPFDV-PGQ 20897 Score = 190 bits (464), Expect = 3e-46 Identities = 239/1083 (22%), Positives = 458/1083 (42%), Gaps = 77/1083 (7%) Query: 629 LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIA-WLFKGEEIVPDENISVA 683 L+ +P F K+ K + E GS + EC++ P I W+ G + E+ Sbjct: 10812 LKAVPLKFVKELKDIVLQEAESIGSSAVFECQIS--PSTAITTWMKDGSNL--RESPKHK 10867 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741 SD L+I +V+ G YT VA N+E ++ +++ E+ P + + L Sbjct: 10868 FTSDGKD--RKLQIIDVQLSDTGEYTCVAKLGNKEKTSTAKLIV-----EELPVKFTKTL 10920 Query: 742 KS-MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796 + M V +G+ + L+ ++ + + W KN K +K + K G S TI + Sbjct: 10921 EEEMSVIKGQPMYLTCEL--SKDRDVVWKKNGKELKQIAGKVQVNVIGLQRSATI-QDTN 10977 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 D GVYT + E+ +T A + + E + PL ++ VK K T + Sbjct: 10978 DDDAGVYTCECED----IKTQANVKIIEIIRDWLTKPL-----RDQHVKPKATATFKCEL 11028 Query: 857 TRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 ++ P+ W++ +E I P+ DG+ I L + N + D G+Y A G+ Sbjct: 11029 YKD-TPNWKWFKGDEEIPTDPTNKTDVKKDGKEITLTVKNAQPD-DIGEY---AIEVEGR 11083 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHRE 974 + A++T+ + +K L E+G+ + + +W + ++ + Sbjct: 11084 R-YTAKLTLGEREAEILKPLASVEVVEKGEANFDTEISEDDIPGEWKLRGQVLTRSPTCD 11142 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034 I EG G + + TS ML VKE +F L+D V EK A Sbjct: 11143 IRAEGNKRFLTLKNVQLDQAGEVSYQALNAVTSAMLTVKEIEMDFTVPLRDVTVHEKKQA 11202 Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 E I + V+W R +I+ + KYD G L I + DEGEY+ + + Sbjct: 11203 KFECTITKDVPKVLWLRGSDIVTSDQ-KYDIIDDGKKHMLVINHCEFEDEGEYTIEVLGK 11261 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 + TA++TV + + ++ + +Q V +G A FE+EL+ V W+K+ +++ S + Sbjct: 11262 TSTAKLTVEGMRLKFVSPISDQTVKEGKTARFELELSHDSVPVTWYKNETKLHPSRTVLT 11321 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 +DGKK L+I D LDD + E TA LTV E FT++L ++ V + + Sbjct: 11322 HVDGKKHILEIKDVTLDDTCQIKAEAKGMSTTANLTVLEGDACFTVKLQDYTAVEKD-EV 11380 Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 L E+ + + V W+ ++ I+ ++ + + K+R L I+K + D+ Y C K Sbjct: 11381 ILDCEL-SKDVPVKWFHNETEIKASKMVAIKVEGKRRILNIKKVEDKDKGLYVCDCGTDK 11439 Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 +++ L +E + K+V + G V+ + +W + +++ Sbjct: 11440 TSSTLNIEARDI--KVVRPMYGVELFDGETARFEVEISE-DDVHGQWKLQGEVLSPSPDV 11496 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + D +LT+ + + +G + N A++++ + +P ++ E D Sbjct: 11497 EIIEDGAKHTLTLYNCKVSQSGEVSFQGANAKCSANLKVKELPISFVTPLADVHVYEKDE 11556 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + E E + + ++ QEI T + + + + + I +K ++Y A Sbjct: 11557 ARF-----ECEISRQAKSFRWLKGSQEIKTDDKFEL--LQEGKRHILVVKA-AAYEDEAK 11608 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 + E + T VI+ +++ +P+K++T + E E + I + +VT Sbjct: 11609 YMFEAE----DNRTSAKLVIQGIRLE---FVRPIKDVTVKERETAEFS-IELSHEKVQVT 11660 Query: 1515 WYRDGKKLKTAKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 WY++ +L +K + + I G+ + + ++ +P Sbjct: 11661 WYKNDVRLHPSKVVHMSEDGKIHTLSFKEVSIDDTSLIKVEALGKTCEAMLTVLEGEPYF 11720 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 T +D K DE ++ + +V W+K+GN++ K I K ++ +K Sbjct: 11721 TTKLQDYTAVEK--DEVVLMCEVSK-SSAQVKWFKDGNEITPSKNVLIKADGKKRILTVK 11777 Query: 1634 ELKRSHSSKYTIE--ASNTAGTSSVE-----VTLKVYD-KPSKPEGPVIMREISRESVTI 1685 + ++ + +Y + + TA ++E + +Y + ++ E EIS E V Sbjct: 11778 KAEKGNIGEYVCDCGSDKTAAKLNIEERDIKIVRPLYSVEVTETETARFETEISEEDVHG 11837 Query: 1686 EWK 1688 WK Sbjct: 11838 HWK 11840 Score = 190 bits (464), Expect = 3e-46 Identities = 113/368 (30%), Positives = 181/368 (49%), Gaps = 10/368 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 I+G P P W G K+++ + I T K + + ++E + YT+ N +GT+ Sbjct: 29394 IKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETTIDDTGDYTLNVKNVSGTA 29453 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + + + + DKP P GP+ + E+ SVT W+PP DGG ++ Y +E+ + W+ Sbjct: 29454 TEVIRVIILDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVEQRDAHRPGWM 29513 Query: 1715 KVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 V++ V R V + +L E EY+FRV A N G L+SE + K+ VP Sbjct: 29514 SVSESVTRPV--FKFTRLVEGTEYVFRVAATNRFGIGGFLQSEVVECKSVKTVPGAPSTP 29571 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSI- 1831 + ++ + +TW P E NGGS I Y +E K+ G +W R + + Sbjct: 29572 EILD-VSHDGMTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPVTMTRYRATGLI 29630 Query: 1832 -NTTYQFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEP 1889 Y++R+ A N GT P +++ K TI + PP P N V+++T SV+L W+ P Sbjct: 29631 EGLEYEYRVTAINSRGTGKP-SANSKPTIAMDPIEPPGIPLNPRVTDTTRTSVSLAWSPP 29689 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 E GG+ +T Y+IE + V WTK T + E+ + ++ + E FR+ A N G Sbjct: 29690 EEEGGAAVTGYLIEMQKVDQVEWTKCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAG 29749 Query: 1950 LPTESQSV 1957 P E V Sbjct: 29750 EPAEIPGV 29757 Score = 189 bits (460), Expect = 8e-46 Identities = 168/697 (24%), Positives = 294/697 (42%), Gaps = 40/697 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436 KP PP P + + +S+ + W +P G I Y+VE E+ + EW+ IT+T Sbjct: 22473 KPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITET 22532 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493 + + L Y+FR AVN++ + + ++ VI E K+++P ++ K IT Sbjct: 22533 RFEAKKLLEKHEYKFRICAVNKIGVGETADIPG--SVIIEDKLEAPDIDLDADLRKMITV 22590 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCI 1551 + L G P P+V W + +G+ + A+ + Y Sbjct: 22591 RAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLT 22650 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N G V + P + +N +K+ K+ V W + G I K Sbjct: 22651 LENASGTKSAFISVRVLDTPDMP-ANFRVKEITKNSVTLTWEPPLLDGGAKIKSYIVEKR 22709 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKP 1666 + K Y+ T +I+ L+ + + A N G T LK+ + P Sbjct: 22710 ES---TRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGLPAETPEPLKISEVP 22766 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 +P G V + +++R+SV+++W+ P DGG +T Y +E D ++W A V + ++T Sbjct: 22767 -QPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKDQDKWSLCAQV-KALDTV 22824 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 + L + EY+FRVIA N G S+ L + P+V K P+ + Y Sbjct: 22825 -VTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKDLAIEPTVRTKLSTYSV---QVGY 22880 Query: 1786 ITWFPSEKNGG-SPIIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 + +G P I + + +KQ + I+ + + I Sbjct: 22881 DLKIEARISGHPKPTITWNKDGSALKQTTRV-NVADTAHHTTLTIKDATREDGGMYNIVV 22939 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N +G + +I I + PP+ P + E ++ S+TL W P GG I+NYI Sbjct: 22940 ANVLGQQ---EATVEIIILEKPGPPTGPVR--IDEVSAESITLSWDPPTYTGGCQISNYI 22994 Query: 1902 IEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 ++ + +W + TV + + + N+K E FRI AEN G S +S V + Sbjct: 22995 VQKRDTTTTNWVVVSATVARTTLK--VGNLKTGAEYQFRIFAENRYGKSYGIDSDPVLAQ 23052 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 P PP P + ++ W P DGG+ +LGY++ ++ +W ++ K+ Sbjct: 23053 YPFKEPGPPGTPF-VSAFNKESMVVEWHKPVSDGGSAILGYHLERKEKNSILWTKINKIL 23111 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + ++ L E Y R+YA N +G+ + ++ E Sbjct: 23112 IQDTRYKTSPLEEGIEYEFRVYAENIVGIGKCSKTSE 23148 Score = 188 bits (457), Expect = 2e-45 Identities = 175/705 (24%), Positives = 291/705 (41%), Gaps = 46/705 (6%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---IT 1434 +D PS P K +++ +SI + W +P G S I YV+E + D TEW+++ + + Sbjct: 26799 IDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSEITSYVIEQRIADETEWVTISSKGEVR 26858 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-- 1492 T+ + +LK Y +R AVN V + E + V + ++ V+ + T Sbjct: 26859 TTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQ--PVQAKDILEEADVDLDISMSTQY 26916 Query: 1493 -TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX-----XXXXXX 1546 + D+E+ G P P VTW R G K + A Y R Sbjct: 26917 IAKAGRDVEIVIPLKGRPAPNVTW-RKGDKNISGDARYAIRNTEYSTTLIIPKVTRDDTG 26975 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ---KHKVGDEWLVTAVIEGIPPPE 1603 Y N GE +T V ++ + N I + + K+ W + G P Sbjct: 26976 KYLLEIENGVGEPKT-ITVSVKVLDTPSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITN 27034 Query: 1604 VIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVT 1659 + K K+ K + I T E + ++ L S + + A N G E Sbjct: 27035 YVVEKKDAKM---KAFTIVTNECANTTYKVDGLSEEISYFFRVSAENEYGVGDPCETEQP 27091 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 ++ + P + V++ + + SV++ W P DGG + +Y IEK D W Sbjct: 27092 VRATEMPGAIKDLVLV-DSTNTSVSLAWTKPDHDGGSHINEYIIEKKTKDEETWSSGGTC 27150 Query: 1720 DRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778 R C + +L E E FRV A+N G S+ + PI +K L P Sbjct: 27151 RR---CQCEVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEANLIDYPNGE 27207 Query: 1779 ID---NESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSINT 1833 + ++V I P K PII + + I +E ++ + ++ Sbjct: 27208 LSVRIGQNVNID-LPY-KGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKEN 27265 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESN 1892 ++ + N++ + D K+ TL PPSQP + E ++S+ + W P+ + Sbjct: 27266 AGKYTLVLDNKLVKNF---FDIKVI---TLGPPSQPIGPIRFDEIKAQSIIISWDVPQED 27319 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 GG IT Y +E + +W KIV I N+ + E FR+ AEN GVS P Sbjct: 27320 GGGEITCYSVEKRETSQAAW-KIVCSSVVRTTFKIPNLVKGTEYQFRVRAENKYGVSDPL 27378 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 S V + P PP P+ + + + W P +DGG+P+ GY++ +D + Sbjct: 27379 TSPDVVAQHQYKPPGPPGKPVVFNVTSDGMTV-QWDAPGFDGGSPITGYHLEKKDRNSLL 27437 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 WM+V ++ ++ + L E Y R+YA+N G+S E + Sbjct: 27438 WMKVNTSVISGREYRVIGLIEGLEYSFRVYAQNNAGMSPVSEQSK 27482 Score = 188 bits (457), Expect = 2e-45 Identities = 196/807 (24%), Positives = 324/807 (40%), Gaps = 60/807 (7%) Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI 1338 K+++ P KIV+ + G + L + + P P W K+ K K Sbjct: 29369 KIDLTGIPQKIVN------VPAGKPIVLNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIET 29422 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSI 1397 +K LT+++ D G Y L ++N G A + V ILDKP P G I E+D++S+ Sbjct: 29423 TAKFTKLTVRETTIDDTGDYTLNVKNVSGTATEVIRVIILDKPGVPVGPMKIEEVDATSV 29482 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAV 1456 W+ P+ G + + Y+VE ++ W+SV +++T+ L + Y FR A Sbjct: 29483 TCSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGTEYVFRVAAT 29542 Query: 1457 NEVDISD--ASETTEYYKVIKETKIQSPTVEKPLK------NITTEPNEDIELTCIFGGV 1508 N I SE E V +T +P+ + L +T P ED + I G + Sbjct: 29543 NRFGIGGFLQSEVVECKSV--KTVPGAPSTPEILDVSHDGMTLTWTPPEDNGGSTIAGYI 29600 Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 + K + T Y+ A N G + S Sbjct: 29601 IERKEAGSDRWLSINKNPVTMTR---YRATGLIEGLEYEYRVTAINSRGTGKPSA----N 29653 Query: 1569 QKPVIT---ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNIT-T 1623 KP I I I +V D + + PP E G +E K + T Sbjct: 29654 SKPTIAMDPIEPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVTGYLIEMQKVDQVEWT 29713 Query: 1624 KEKTSVIRIKELKRSHSS-----KYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPV-- 1673 K T+ +I E +H K+ + A N G + + +KV + P+ + Sbjct: 29714 KCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEK 29773 Query: 1674 IMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731 I +E + R+ I P+ L K+ E + + I ++ ++ I++ Sbjct: 29774 IYQEGYVVRQGGVIRLSVPIKGKPLPTCKWTKEGRDISHRAMIATSEERTEL---VIKEA 29830 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXIDNESVYITWFP 1790 + + + ++ +N G + + IK + P I SV ++W P Sbjct: 29831 HRDDTGTYDLVLENKCG------RKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRP 29884 Query: 1791 SEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK-LSINTTYQFRIYARNEIGTS 1848 +GGS I Y VE ++ K W + + K L N Y F+I A N+ G S Sbjct: 29885 PSDDGGSDIFGYIVERREVPKAAWYTVDSRVVDTSLVVKGLKENVEYHFKITAENQFGIS 29944 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 SD+ +T L PP +P +F + + T ++ L W+ P+ +GGS +T Y +E + Sbjct: 29945 KSLKSDESVTPKTPLCPP-EPPSFPPEIMDVTKTTIGLSWSRPKDDGGSRVTGYYVERRE 30003 Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATV 1965 + + W + + + + + E FR+ A+N +G S P S+SV + Sbjct: 30004 ISTEKWVRHNKTHITTTMYTLTGLIPDAEYQFRVVAQNDIGQSEPGPVSESVVCKDPFDK 30063 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P P +I + + + W PE DGG +LGY I R ++ W + K + Sbjct: 30064 PGQP-GEFDIISITKDSITIHWLRPESDGGKEILGYWIEFRQAGESAWKKCNKERSKDRQ 30122 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEP 2052 F I L E Y R++A NE GLS P Sbjct: 30123 FTIGGLMEATEYEFRVFAENETGLSRP 30149 Score = 187 bits (456), Expect = 3e-45 Identities = 122/401 (30%), Positives = 183/401 (45%), Gaps = 15/401 (3%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 +VG+ ++ + G P P + W+KN +L+ ++E +TT + + I++ KR HS KY Sbjct: 16500 RVGETCIIQSRYTGKPEPTIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKRDHSGKYM 16559 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + N+ GT T+ V D+P PEGPVI EI R + I W PPLDDGG ++ Y +E Sbjct: 16560 VVLENSIGTRKGICTVNVVDRPQPPEGPVIFDEIYRNYMVISWNPPLDDGGAAISNYIVE 16619 Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 K + + + W+ V + T C + KL E EY+ R+ AQN G S+ L S K Sbjct: 16620 KRDTNRDLWMPV--TESCTRTSCKVPKLIEGREYIIRICAQNIHGISDPLLSAETKAKDV 16677 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXX-- 1820 VP I ++ I+W +GG PI +Y VE K+ + W Sbjct: 16678 FKVPD-APQAPVVKEIYKDTALISWL-QPADGGKPITNYIVEKKETKANMWARAGKDRIF 16735 Query: 1821 -XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 + L Y+FR+ A N IG P S I + PS P V + T Sbjct: 16736 PNTEYWVPDLLKGCEYEFRVMAENVIGIGDPSPSSKPIYAKDPIVIPSPPVLPVAIDKTK 16795 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII-- 1937 SVTL W P+ G I Y++E++ + W ++ S + I +D + Sbjct: 16796 ESVTLSWQPPKDCGRGKIFGYLLEYQKAGDEEWLQVNQTPDSCPSTTFKVINLEDGALYR 16855 Query: 1938 FRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRM 1977 FR+ A N G S P + VR + PP L++ M Sbjct: 16856 FRVKAVNAAGESEPAYVPEPVRAQDRF---EPPELQLDLGM 16893 Score = 187 bits (456), Expect = 3e-45 Identities = 228/970 (23%), Positives = 395/970 (40%), Gaps = 70/970 (7%) Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 IE+ K +L W + ++ H ++T ++ K C ++ AG+ A Sbjct: 27922 IEMCKA-SLEEWHRVNNQTCIQTHYRVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQA 27980 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLIS 1246 + + P I+ + +V L + + + + TW K + Sbjct: 27981 VDRLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTD 28040 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP--PKIVDYEREYRIKRG 1302 TL I CT D +YT L + + T L V+V++ P P + ++ + RG Sbjct: 28041 TFS--TLTIENCTRYDAGKYTLSLENNSGRKTITLTVKVLDTPGPPGPLSFKD---VTRG 28095 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT--IKKVENTDAGI--- 1357 + +TL+ D P + V+ I++K + ++ S S T I +V N D G+ Sbjct: 28096 A-LTLMWDA---PSNDGGARVHHYIVEKREASRLSWQEVSERCTRQILRVINLDIGVAYF 28151 Query: 1358 YKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +++ EN G + EM I+ ++P+ P + ++++ S++ ++ W +PE+ G S I Sbjct: 28152 FRVTAENQYGKGEPYEMTEPIIATEEPASPKRLDVIDTTSTTASLVWMKPEHDGGSRITG 28211 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 Y+VE ++ + W+ + ++ L N+ Y FR A N+ IS + +I Sbjct: 28212 YIVETRKKGSANWVFGGQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASV-II 28270 Query: 1475 KETKIQS----PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATY 1529 KE +I+ +++K L IT + + G P PKVTW + KLK T + + Sbjct: 28271 KEPRIEPTADLSSIDKQL--ITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSI 28328 Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VETSCVVGIQQKPVITISNEDIKQK 1583 ++R Y N G T V+G P + + + Sbjct: 28329 KISKDRTTLLVKDAKRGDSGKYYLTLENAAGSKTFTVTVIVIGRPTPPTGPVEISGVSSE 28388 Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 V W + G I K + + N + K T I++ L + + Sbjct: 28389 SCV-LTWGEPSDDGGTDITNYIVEKRESGSTTWQVVNSSVKRTT--IKVTHLTKYMEYTF 28445 Query: 1644 TIEASNTAGTS-SVE----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 + A N G S S+E V + PS P P ++ + +++I W P DGG ++ Sbjct: 28446 RVSAENKFGVSKSIESQAIVAEHPFISPSPPTRPDVV-SVCANAISIRWDVPYHDGGSQV 28504 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEP 1757 T Y IEK E + W++ + Y + L E EY FRV A N G S+A E S P Sbjct: 28505 TGYWIEKKERNTILWVRENKIPCVECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRP 28564 Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK----QEGKKW 1813 ++ +D P + SV I W +GGS I+ Y VE K E +W Sbjct: 28565 VLALNPVDPPG----TPEVYDVTKTSVSIRWSVPFNDGGSKIVGYVVERKASSDDEEARW 28620 Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP-SQP 1869 + L Y+FR+ ARN G S+P S IT TPP ++ Sbjct: 28621 LKCNYTTITENFFTVTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKAEL 28680 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYII---EFKTVKGKSWTKIVTVGGSVHEHC 1926 + +V E+ S + GG P + + G+ ++ +T + Sbjct: 28681 DSKLVGETISIRAGSDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYS--LTYTSTRAMAI 28738 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I++ D + ++ +N G+ T + +V++ P PP + I V S Sbjct: 28739 IKSCDRNDTGRYILTVKNASGIK--TSAVNVKV---LDTPGPPAGTITISRVTDEKCTVS 28793 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P DGG + Y + R+ ++ W+ + + + TL L +N+ Y+ R+ N+ Sbjct: 28794 WKIPLEDGGDHVSHYIVERRETSRLNWV-IMETECKTLSCVSTKLIKNNEYIFRVRGVNK 28852 Query: 2047 IGLSEPLESD 2056 G PLES+ Sbjct: 28853 YGPGVPLESE 28862 Score = 183 bits (446), Expect = 4e-44 Identities = 168/700 (24%), Positives = 293/700 (41%), Gaps = 46/700 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQ 1437 P PP P + + S+++++ W P G + + Y+VE ++I+ EW + T Sbjct: 24638 PGPPNNPKVTDHSSTTVSLAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATH 24697 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY-KVIKETKIQSPTVEKPL---KNITT 1493 +++ LK N+ Y FR AVN I A E + VI K+++P +E K +T Sbjct: 24698 FTVKKLKENAEYNFRICAVN---IEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTV 24754 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCI 1551 + + L G P+P+V W + DG + A+ Y Sbjct: 24755 RASATLRLFVTIRGRPEPEVKWKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLT 24814 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N+ G V + P ++ E D+K + V +W + G I K Sbjct: 24815 LENNIGSKSAFVNVKVLDSPSAPVNFEVKDVK-RDSVQLQWEPPQIDGGAKITHYIVEKR 24873 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVT--LKVYDKP 1666 +K +IT + IR+ +L+ + + A N G E T +K+ P Sbjct: 24874 ESK--RLAFTSITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKISQAP 24931 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 P G + + +++R +VT+ W+ P DGG ++T Y +E +++W + T Sbjct: 24932 LPP-GKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKWTACVTIKALEAT- 24989 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 I+ L EY FR+ A N G +S+P L P ID ++ Sbjct: 24990 -IEGLTTGEEYSFRITAINDKG-----KSDP----KPLGAPVVARDITIEPIID--LMFN 25037 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQFRIY--ARN 1843 T+ S K G ID + + WK R+ L+ T + I R Sbjct: 25038 TY--SVKAGDDLKIDVPFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATRE 25095 Query: 1844 EIGT-SLPYTSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 + G + T+ + + L P P V E ++ ++L W P +GG I Sbjct: 25096 DAGKYEITLTNTFGVKSAEISVIVLDKPGPPGAIKVEEISADFISLSWDPPIYDGGCQIN 25155 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 NY++E + +W +IV+ + + + + E FRI+AEN G S +S + Sbjct: 25156 NYVVEKRDTTTTAW-QIVSATVARTSIKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIV 25214 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + T P PPT+ L++ + ++ +W P DGG+P++GY+I +D + +W ++ + Sbjct: 25215 AQYPFTPPGPPTS-LQVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNR 25273 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + +F + L E Y R+YA N G+ ++ +P Sbjct: 25274 GLITETQFKVTGLEEGLQYQYRVYAENIAGIGPCTKACDP 25313 Score = 180 bits (437), Expect = 5e-43 Identities = 222/991 (22%), Positives = 385/991 (38%), Gaps = 97/991 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V E ++EC VA P + WL G + D + V E + + IT + Sbjct: 2404 VAESQTAVMECE-VANPTSEGKWLKDGHSV--DFSDIVRSEDIDAVRRLIFVITRPQDIG 2460 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 E TY V N + A+L + E ++ + LK+ V + + + S ++ Sbjct: 2461 EYTYQVA--NSKTSANLRV---------EAVKIKKTLKNQTVTETQEAVFSLELTHLDVK 2509 Query: 765 TITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 W KN +P DG H++ I K +DE VY K G +A + Sbjct: 2510 GSQWIKNGVEIEPSDKYEITVDGLVHTLKI-KNCNSQDESVYGFKL----GKLSANARLN 2564 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 VE T + + P +++T GT ++ + +P + W N+ + PS + Sbjct: 2565 VE--TIKIVKKP------KDVTSLVNGTASFELSLSHDDIP-VKWMFKNQELKPSANVQI 2615 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + + +LVI NV+ E + G+Y V + + VE + K L K+ E Sbjct: 2616 MSERKAHKLVIQNVE-ESNDGEYTAVVGHLQ------CSAYLHVESLRVTKPL-KNLEVP 2667 Query: 942 EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 E EC+ SH V + W N EI + I+ +G+ D + Sbjct: 2668 ETHVATFECEVSHFNVPSTWLKNGVEIEMSEKFRIVVQGKLHQLKIMNTSRDDSAEYTFV 2727 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 + + S L V + L+D +EKD EV +N E W ++G I+ Sbjct: 2728 CGNDKVSATLTVSPVL--ITSMLKDLNAQEKDTITFEVTVNYEGITYKWLKNGVEIR-SS 2784 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 ++ + L IRN D G+Y + A++ V E +++ KV + Sbjct: 2785 DRCQTRTKQLSHSLTIRNVHFGDVGDYKFVAGSAETAAKLFVEARVIEFTKHIKDIKVTE 2844 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 KA FE EL++ + V W KDG E++ S +++ + +L I + DAGEYS Sbjct: 2845 KKKAVFECELSEPNVQVTWMKDGQELELSERYKVSTERHVHRLMIQTVRMSDAGEYSVVA 2904 Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT- 1239 G+S A LTVE + + + I V + E+ ++ ++ W + I+ + Sbjct: 2905 GSSVSKANLTVEGKDVRISEPAEKEITVLEKQRSTFEFEVNEDDIEGRWLRNGVEIQFSV 2964 Query: 1240 -EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298 ++F K L I + D EYT + +S L V + E PP+I+ + + Sbjct: 2965 DQRFNYAIIRKIHRLTITETYRSDAGEYTFIAGKNRSIVTLHVNIPE-PPQIIRHMQPLS 3023 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK---KCKHTKPSIDSKSASLTIKKVENTDA 1355 ++ G V+ PQP W NS+ + KCK + + +L + +V DA Sbjct: 3024 VEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLR---EGNEHTLLLIEVFPEDA 3080 Query: 1356 GIYKLRLENNCGHA--DVEMNVTILDKPSP----PGKPNIL--EIDSSSIN---ICWDEP 1404 Y +N+ G A +NV + + SP P P ++ I ++S N + Sbjct: 3081 AQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQC 3140 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE----- 1458 +G I + + +EI ++ V + Q I + + A N Sbjct: 3141 RVSGEDLTITWYCKDKEIKQSDIFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVS 3200 Query: 1459 ----VDISDASETTEYYKVIKETKIQSP-----TVEK-----------PLKNITTEPNED 1498 + + +E +Y SP T++K P+ + E Sbjct: 3201 CSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTIQKDAIGQKPSFFQPIMSSVVAHGEV 3260 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE-----NRXXXXXXXXXXXXXXXYKCIA 1552 G+P+P+++W+ + + +K T Y N Y C A Sbjct: 3261 ARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKA 3320 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583 N GE S + + ++ +T E+I+ K Sbjct: 3321 VNIRGEAACSANLAVTEE--VTRVREEIEAK 3349 Score = 179 bits (436), Expect = 7e-43 Identities = 213/911 (23%), Positives = 361/911 (39%), Gaps = 70/911 (7%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250 E P + L +P + A T + I VTW K ++ + + K Sbjct: 16883 EPPELQLDLGMPRELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETSGTTTK 16942 Query: 1251 RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 L +R C D +YT + + A S +V P V + R ++ S Sbjct: 16943 --LEMRYCNRTDCGDYTLTVENPAGSKIATCTVLVLDKPGPVQHLRVSDVRSDSAQLSWK 17000 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPS-----IDSKSASLTIKKVENTDAGIYKLRLEN 1364 D P+ N + + +++K P SK S+ K + + ++++ EN Sbjct: 17001 D----PEDNGGARITNFVVEKKDAASPQWVPICSSSKKRSMMAKHLIEGTSYMFRVAAEN 17056 Query: 1365 NCGHAD-VEMNVTI--LDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVE 1418 G ++ VE I ++ PPG P L + D + + + W+ P+ TG S I ++VE Sbjct: 17057 QFGRSEYVETTKAIKAMNPLFPPGPPKDLHHVDADKTEVWLQWNWPDRTGGSDITGFLVE 17116 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 YQE +WI K ++ + + L+ +YRFR N + +S T V+ + K Sbjct: 17117 YQEEGEKDWIVFKTVSIPECHVTGLEEGKTYRFRVKTENAIGLSRPDTTV---PVLCQEK 17173 Query: 1479 IQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYEN- 1531 + P VE K ++ I + I L + G+P P W DG+++K+ K +N Sbjct: 17174 LVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKIDTDNF 17233 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDE 1589 Y N G S V + P I +I + + + Sbjct: 17234 STVLSIADCTRNHTGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILEVTPDSMVID 17293 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEA 1647 W G P I K E++KE +++ ++ ++I L++ I A Sbjct: 17294 WRPPKDDGGSPVMNYI----VEKRESNKETWGGVSSGSTSTRLKISRLQQGVEYVVRIRA 17349 Query: 1648 SNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 N G S+ V ++ P P PV ++S +++T+ W PL DGG ++ Y Sbjct: 17350 ENKMGIGAALESAPTVARHQFEAPGHPGKPV-ASDLSEDALTLGWTMPLFDGGSPISGYI 17408 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIK 1761 IE+ +WI+V Y + L E EY FRV A+N GFS + S+P Sbjct: 17409 IERRH-KGGKWIRVNKTPCKELRYRVLGLFEGNEYEFRVFAENIAGFSGPSPVSDPAKPC 17467 Query: 1762 TALDVPSXXXXXXXXXXIDNESVY--ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX 1819 + VP D Y + W K+GGSP++ Y VE ++ G +W+ Sbjct: 17468 RPITVPGPPVNPKVK---DYSCTYADLVWIKPTKDGGSPVLGYIVECQKGGAEWEKVNKD 17524 Query: 1820 XXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 R++ L+ +T Y+FR+ A N IG + + + PP + Sbjct: 17525 DLIKQCAYRVKGLTEDTEYRFRVKAVNMIGEGETREIPESVIAKDIIIPP----EIEMDA 17580 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK-----IVTVGGSVHEHCIENIK 1931 + VT++ + G E KG+S + ++T V + I+ Sbjct: 17581 TCHERVTVRVGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNFPVVQMRIKEAT 17640 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 D + + A N G + T + +V L++ + L++ V N M SW PE Sbjct: 17641 RADHGKYVLKAVNEAGEASATITVNV-LDRPGHCQN-----LKMTYVTKNSCMVSWDAPE 17694 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 +GG+ + Y + R+ + W + N + L ENH Y+ R+ A N+ G Sbjct: 17695 DNGGSEITNYIVECREPSIRTWAMISSDCTN--RMVKAKLMENHEYLFRVSAENKCGPGP 17752 Query: 2052 PLESDEPFKVI 2062 E+ P I Sbjct: 17753 ATETKTPILAI 17763 Score = 176 bits (428), Expect = 6e-42 Identities = 208/934 (22%), Positives = 376/934 (40%), Gaps = 65/934 (6%) Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 + + +I +++ AGE+ G+ L E ++ LR + A ++ Sbjct: 24705 ENAEYNFRICAVNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFV 24764 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AK 1274 T+ E +V W K + + + + L+I D +Y L + Sbjct: 24765 TIRGRPEP-EVKWKKADGTLPERAQIEVTGSYTG--LVIDNVNRFDTGKYVLTLENNIGS 24821 Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND------EWIVNSKII 1328 + + V+V++ P V++E + +KR S V Q P D +IV + Sbjct: 24822 KSAFVNVKVLDSPSAPVNFEVK-DVKRDS-----VQLQWEPPQIDGGAKITHYIVEKRES 24875 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDKPSP 1383 K+ T SI + +I+ + + G+Y R+ N G A+ V I P P Sbjct: 24876 KRLAFT--SITNNCVRNSIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKISQAPLP 24933 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL 1443 PGK ++++ ++ + W++P++ G S I Y+VE + +W + I + +I+ L Sbjct: 24934 PGKITVIDVTRHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKWTACVTIKALEATIEGL 24993 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 T Y FR A+N+ SD V ++ I+ P ++ + + +D+++ Sbjct: 24994 TTGEEYSFRITAINDKGKSDPKPLGAPV-VARDITIE-PIIDLMFNTYSVKAGDDLKIDV 25051 Query: 1504 IFGGVPQPKVTWYRDGKKLK-TAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHG-- 1557 F G P P+VTW +DG LK T + T + Y+ N G Sbjct: 25052 PFRGRPSPEVTWKKDGHSLKQTTRVNVLTSKTLSKITIKDATREDAGKYEITLTNTFGVK 25111 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 E S +V + P I E+I + W G + K + Sbjct: 25112 SAEISVIVLDKPGPPGAIKVEEISADF-ISLSWDPPIYDGGCQINNYVVEKR-DTTTTAW 25169 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMR 1676 + T +TS I++ L + ++ I A N G S +++ V P P GP Sbjct: 25170 QIVSATVARTS-IKVSRLTQGTEYQFRIAAENRYGKSHAIDSAPIVAQYPFTPPGPPTSL 25228 Query: 1677 EIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733 ++S + + + W P DGG + Y IE + + W K+ + + L E Sbjct: 25229 QVSHATKSGMLVTWNRPASDGGSPIVGYHIECKDQSSILWTKMNRGLITETQFKVTGLEE 25288 Query: 1734 NCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 +Y +RV A+N G ++ +P+ + PS I SV ++W E Sbjct: 25289 GLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPS----QPRVMNITRTSVSLSWTKPE 25344 Query: 1793 KNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-S 1848 +GG+ + Y VE + +G+ K + L + Y FRI A+N G S Sbjct: 25345 FDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRYDFRIIAKNAAGLFS 25404 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-----PESNGGS-PITNYII 1902 P S +T+ + PP + + + V +K E E +G P+ ++ Sbjct: 25405 EPSESTGPVTVKDDVDPP----RITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAK 25460 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + K ++ K+ +I + S + + +D + ++ +N G T S +V K Sbjct: 25461 DGKEIEAKARFEISSTLTST-TLIVRDAIRRDSGQYVLTLQNVAG----TRSLAVNC-KV 25514 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 P P + PL+I + + +WG P+ +GGA + Y + R+ ++ W V D+ Sbjct: 25515 LDRPGPSSGPLDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLV-YADMK 25573 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + L + + Y+ R+ N+ G E LESD Sbjct: 25574 ATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESD 25607 Score = 175 bits (426), Expect = 1e-41 Identities = 196/849 (23%), Positives = 334/849 (39%), Gaps = 56/849 (6%) Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TK-LKVEVVEFPPKIVDYEREYRIKR 1301 L+SD +K +L I++ DD YT ++ T TK +K+ ++ P V IK Sbjct: 15946 LVSD-EKCSLFIQQSKRDDSAMYTLTATNSLGTATKSIKLSILGRPGVPVG-----PIKI 15999 Query: 1302 GSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDA 1355 G + P +D I N + K+ ++ K S D K ++++ Sbjct: 16000 GEVFAERIGLSWNPPADDGGSKITNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHE 16059 Query: 1356 GIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 +++ +N G +++ E + P PP P + + S++++ W P N G S Sbjct: 16060 YEFRVMAQNKYGVGPPLYSEPEKARNLFTPPGPP-TPKVTDCTKSTVDLEWIPPLNDGGS 16118 Query: 1411 TIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 I Y VEY++ EW VK+ I T+ + LK YRFR AVN + + E Sbjct: 16119 MITGYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVA 16178 Query: 1469 EYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTA 1525 + +V T ++ +K I I + G P P++ W RD +L + A Sbjct: 16179 DVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAA 16238 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---VITISNEDIKQ 1582 T Y A N GE + + +V + P + S E++ Sbjct: 16239 VETTSISSALVIKSCLRQHQGIYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENL-T 16297 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 W G I K T +V ++ L Sbjct: 16298 NDSCKLTWYSPEDDGGSAITNYIIEKREADRRGWTSVTYTVTRHNAV--VQGLIDGKGYF 16355 Query: 1643 YTIEASNTAGTSSVEVT---LKVYDKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLE 1697 + I A N G T + + D S PE P V + I+ +S+++ W+ P DGG + Sbjct: 16356 FRIAAENIIGMGPFTETAAPVVIKDPLSVPERPEDVEVTAITNDSISVAWRSPKYDGGSD 16415 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSE-ALES 1755 +T Y +E + + ++A D+ ++ + L E Y FRV A N +G + + + Sbjct: 16416 ITSYVLEVRLIGQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFST 16475 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDY--KVEIKQEGKK 1812 +P+ K + P+ + I S G P I + E Q ++ Sbjct: 16476 KPVTCKKEFEPPNLDLEFRDKLVVRVGETCI--IQSRYTGKPEPTIKWFKNDEELQANEE 16533 Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 I+K + + ++ + N IGT + + + PP P Sbjct: 16534 IALTTAKNRLSLTIEKAKRDHSGKYMVVLENSIGTRKGICT---VNVVDRPQPPEGP--V 16588 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIK 1931 + E + + W P +GG+ I+NYI+E + W + C + + Sbjct: 16589 IFDEIYRNYMVISWNPPLDDGGAAISNYIVEKRDTNRDLWMPVTE--SCTRTSCKVPKLI 16646 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 E E I RI A+N G+S P S + + VP P AP+ ++ + + + SW P Sbjct: 16647 EGREYIIRICAQNIHGISDPLLSAETKAKDVFKVPDAPQAPV-VKEIYKDTALISWLQPA 16705 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGK--VDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 DGG P+ Y + ++ MW GK + NT ++ + DL + Y R+ A N IG+ Sbjct: 16706 -DGGKPITNYIVEKKETKANMWARAGKDRIFPNT-EYWVPDLLKGCEYEFRVMAENVIGI 16763 Query: 2050 SEPLESDEP 2058 +P S +P Sbjct: 16764 GDPSPSSKP 16772 Score = 174 bits (424), Expect = 2e-41 Identities = 177/702 (25%), Positives = 283/702 (40%), Gaps = 47/702 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS- 1439 PS P +++ +S+ + W +P G II Y++E + EW V N T QT Sbjct: 27886 PSAPTLVKVIDSTKTSVTLAWTKPVFDGGLEIIGYIIEMCKASLEEWHRVNNQTCIQTHY 27945 Query: 1440 -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + L++ Y+FR AVN + SET + + ++ K N Sbjct: 27946 RVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGG 28005 Query: 1499 -IELTCIFGGVPQPKVTWYR-DGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 ++L F G P P TW + DG + T + Y N+ Sbjct: 28006 TVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENN 28065 Query: 1556 HGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 G + V + P +S +D+ + + W + G I K Sbjct: 28066 SGRKTITLTVKVLDTPGPPGPLSFKDVT-RGALTLMWDAPSNDGGARVHHYIVEKREASR 28124 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 + +E ++ + ++R+ L + + + A N G + +P P Sbjct: 28125 LSWQE--VSERCTRQILRVINLDIGVAYFFRVTAENQYGKGEPYEMTEPIIATEEPASPK 28182 Query: 1674 IMREISRESVT--IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731 + I S T + W P DGG +T Y +E + + W+ + ++ ++ L Sbjct: 28183 RLDVIDTTSTTASLVWMKPEHDGGSRITGYIVETRKKGSANWV-FGGQTKSLKMV-LEGL 28240 Query: 1732 NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 EN EY FRV AQN G S+ ++ ++IK P+ ID + + Sbjct: 28241 VENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSS-----IDKQLITC---- 28291 Query: 1791 SEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQ-KLSIN-TTYQFRIYARNEIGT 1847 K G S ID + + K WK R+ K+S + TT + R + G Sbjct: 28292 --KTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDAKRGDSGK 28349 Query: 1848 ---SLPYTSDDK------ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 +L + K I IG+ TPP+ P +S +S S L W EP +GG+ IT Sbjct: 28350 YYLTLENAAGSKTFTVTVIVIGRP-TPPTGPVE--ISGVSSESCVLTWGEPSDDGGTDIT 28406 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQS 1956 NYI+E + +W V SV I+ ++ + E FR+SAEN GVS ESQ+ Sbjct: 28407 NYIVEKRESGSTTWQ---VVNSSVKRTTIKVTHLTKYMEYTFRVSAENKFGVSKSIESQA 28463 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + E PSPPT P ++ V +N + W P DGG+ + GY I ++ +W+ Sbjct: 28464 IVAEHPFISPSPPTRP-DVVSVCANAISIRWDVPYHDGGSQVTGYWIEKKERNTILWVRE 28522 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 K+ + + L E Y R+YA N GLS+ E P Sbjct: 28523 NKIPCVECHYKVSTLIEGLEYQFRVYAMNIAGLSKASEPSRP 28564 Score = 173 bits (422), Expect = 3e-41 Identities = 184/722 (25%), Positives = 288/722 (39%), Gaps = 51/722 (7%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---- 1433 L PS P P I + S+ + W P G I Y++E Q+ T+EW V + Sbjct: 15475 LTPPSMPAAPEIADKTKHSVTLAWTPPAKDGGRPIKGYIIEIQDEGTSEWARVNDAENLH 15534 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KN 1490 T +I NL YRFR AVNE+ S+ S T + I++ K +P + + + Sbjct: 15535 PSTVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVR-IEDIK-TAPKIFMDISADEL 15592 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550 + ++ G P PKVTW DGK K Sbjct: 15593 LCVRAGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTSVVTVP 15652 Query: 1551 IAFNDH-GEVETSCVVGIQQKPV-ITISNEDI---KQKHKVGDEWLVT-AVIEGIPPPE- 1603 ++ H G + QK V + ++ D+ ++ KV D T +I +P + Sbjct: 15653 VSLRSHSGRYTITAKNKSGQKHVNVRVNVLDVPGAPKELKVTDVTRTTMRLIWKLPDNDG 15712 Query: 1604 ---VIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS-VEV 1658 + Y K N K + + S+ + L + + A N G E Sbjct: 15713 GERIKSYFIEKKAVNGKAWTVANATCASMAFVVSNLLEGQDYFFRVRAENRLGFGPFTET 15772 Query: 1659 TLKVYDK----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK-----HEPD 1709 T V + P P V + +++ +VT+ W PP +DGG + Y IE+ P Sbjct: 15773 TEPVRARDPIYPPDPPTKVKINLVTKNTVTLTWVPPKNDGGAPVKHYIIERLSWDTSGPQ 15832 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768 W + D + T+ I+ L E EY FRV A N G S ++ + PIVIK PS Sbjct: 15833 KETWKQCNKRDVEETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPS 15892 Query: 1769 XXXXXXXXXXIDNESVYITW------FPSEKNGGSP--IIDYKVEIKQEGKKWKXXXXXX 1820 + V I FPS +P D KV + Q K Sbjct: 15893 IDLREALEGA-EGFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPV-QYDKHVNKLVSDE 15950 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTS 1879 IQ+ + + + + A N +GT+ T K++I L P P + + E + Sbjct: 15951 KCSLFIQQSKRDDSAMYTLTATNSLGTA---TKSIKLSI---LGRPGVPVGPIKIGEVFA 16004 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 + L W P +GGS ITNY++E + K+W V+ ++ ++ + E E FR Sbjct: 16005 ERIGLSWNPPADDGGSKITNYVVEKREENRKTWVH-VSSDPKECQYIVQRLTEGHEYEFR 16063 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 + A+N GV P S+ + T P PPT ++ + V W P DGG+ + Sbjct: 16064 VMAQNKYGVGPPLYSEPEKARNLFTPPGPPTP--KVTDCTKSTVDLEWIPPLNDGGSMIT 16121 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 GY + + + W +V ++ KF + L E Y R+ A N G+ EP E + Sbjct: 16122 GYFVEYKQEGQEEWEKVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVI 16181 Query: 2060 KV 2061 +V Sbjct: 16182 EV 16183 Score = 173 bits (420), Expect = 6e-41 Identities = 166/712 (23%), Positives = 286/712 (40%), Gaps = 53/712 (7%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT-----EW--ISVKNI 1433 P PP K I + +++ + W P+N G + + +Y++E DT+ W + +++ Sbjct: 15785 PDPPTKVKINLVTKNTVTLTWVPPKNDGGAPVKHYIIERLSWDTSGPQKETWKQCNKRDV 15844 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 +T I++LK Y FR AVNE S S T + +T S + + L+ Sbjct: 15845 EETTFIIEDLKEGGEYEFRVKAVNEAGASRPSVTAGPIVIKDQTCAPSIDLREALEGAE- 15903 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYR------DGK-----KLKTAKATYENRXXXXXXXXXX 1542 D+ + G P P + W++ D K K + + Sbjct: 15904 --GFDVNIVARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKR 15961 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIP 1600 Y A N G S + I +P + + I + ++G W A G Sbjct: 15962 DDSAMYTLTATNSLGTATKSIKLSILGRPGVPVGPIKIGEVFAERIGLSWNPPADDGG-- 16019 Query: 1601 PPEVIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----S 1654 ++ Y + EN K + ++++ K ++ L H ++ + A N G S Sbjct: 16020 -SKITNYVVEKREENRKTWVHVSSDPKECQYIVQRLTEGHEYEFRVMAQNKYGVGPPLYS 16078 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 E ++ P P V + ++ +V +EW PPL+DGG +T Y +E + W Sbjct: 16079 EPEKARNLFTPPGPPTPKVT--DCTKSTVDLEWIPPLNDGGSMITGYFVEYKQEGQEEWE 16136 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 KV D + + + L E Y FRV A N G E E ++ +P Sbjct: 16137 KVKDKEIRGTKFVVPGLKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPE----- 16191 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT 1834 +D ++ G I+ Y W A ++ SI++ Sbjct: 16192 ----VDLDATVKEKIVVHAGGVIRILAYVSGKPAPEIIWNRDDAELPKEAAVETTSISSA 16247 Query: 1835 YQFRIYARNEIGTSLPYTSD-----DKITIGKTLTPPSQPR-NFVVSESTSRSVTLKWTE 1888 + R G + K I + L P F T+ S L W Sbjct: 16248 LVIKSCLRQHQGIYTLTAKNAGGERKKAVIVEVLDVPGPVGLPFSGENLTNDSCKLTWYS 16307 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 PE +GGS ITNYIIE + + WT VT + H ++ + + FRI+AEN +G+ Sbjct: 16308 PEDDGGSAITNYIIEKREADRRGWTS-VTYTVTRHNAVVQGLIDGKGYFFRIAAENIIGM 16366 Query: 1949 SLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 TE+ + V ++ +VP P +E+ + ++ + +W +P++DGG+ + Y + +R Sbjct: 16367 GPFTETAAPVVIKDPLSVPERPE-DVEVTAITNDSISVAWRSPKYDGGSDITSYVLEVRL 16425 Query: 2008 VTKTMWMEVGKVD-VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + + + K D + KF L E +Y R+ A N+IG +P S +P Sbjct: 16426 IGQDNFSRIAKEDKLMDRKFTHAGLKEGSSYEFRVSAVNQIGQGKPSFSTKP 16477 Score = 171 bits (417), Expect = 1e-40 Identities = 197/895 (22%), Positives = 345/895 (38%), Gaps = 52/895 (5%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252 P + +L + I+V A + L E+ + + V W K + ++ E + V + Sbjct: 18962 PRVEISLEMKNLIVVKAGANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHLS 19021 Query: 1253 LIIRKCTEDDQCEYTCVLLD---AKSTT-KLKVEVVEFPPKIVDYEREY--RIKRGSDVT 1306 L + T + EYT + +KS KLKV PP V + R+K + Sbjct: 19022 LELFSVTRKESGEYTITAENPSGSKSANIKLKVLDKPGPPASVRISHVFADRVKLRWEPP 19081 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 L +IV+ + + + +I+ + +++K+ +++ EN Sbjct: 19082 LADGGSEITN----YIVDKRETSRANWAQVTANINGQITDCSVEKLIEGHEYEFRISAEN 19137 Query: 1365 NCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 G D + +++ D P P P I + + + W P N G +TI+ Y+VE Sbjct: 19138 KYGVGDPIVTSSVMAKNPFDVPGPCEPPVITNVTRDHMTVTWKAPANDGKATILGYMVEK 19197 Query: 1420 QEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E W+ V +I+ L + Y FR A+N+ + S+ + + Sbjct: 19198 RETQDLNWVKVNRRPVIDRTIKAGGLTEGTEYEFRVIALNKAGLGKPSDPSSGVLALDPV 19257 Query: 1478 KIQSP-----TVEKPLKNIT---TEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAK 1526 P V+ +I+ T+P D I G + + K + K K + Sbjct: 19258 YPPGPPAFPKVVDSTHSSISLSWTKPAYDGGCE-ILGYLVEFKRADAEEWMKCNVPKNLQ 19316 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKH- 1584 AT N I F + EV E I P + + D+++ Sbjct: 19317 ATKFNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPEKHLAKDILLAPEAEL-DADLRKALV 19375 Query: 1585 -KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 + G + + G P P+ W K L+ + I T E + + +++ R + KY Sbjct: 19376 LRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYDAGKY 19435 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 + N++GT S + +KV D P P +I++E S++ V+I W PL DGG + Y + Sbjct: 19436 VLTLENSSGTKSYTIVVKVLDTPGPPVN-LIVKETSKDHVSITWDAPLIDGGSPVKSYVV 19494 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 EK + W VA + ++ I L Y FRV+A+N G E E+ V A Sbjct: 19495 EKRLAERKAWTCVAP-ECPKTSFRITNLEAGQAYCFRVLAENIYGIGEGCETAGPV--KA 19551 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXX 1823 + P I S + W +GGS ++ Y +EI + KWK Sbjct: 19552 SEQPG-PVAEFKSMEITKNSCTLGWKKPISDGGSHVVAYALEICEGEDKWKLLMKSKVTQ 19610 Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRS 1881 I L Y FR+ A NE P ++ I + PP+ + S Sbjct: 19611 YTIGDLVEGKEYSFRVKAINESAEGPP--TELTILAKDQIVPPNCDLKGLPDSSYVAKEG 19668 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 T++ P + +P + T+ + + + I + D F I Sbjct: 19669 TTVRLNIPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNT-VLLIRDCHRGDAGKFTII 19727 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 N+ G T+ ++ + K P + P++ + + + WG P+ DGG+ + Y Sbjct: 19728 LRNSAG----TKEAAIDI-KVVGKPGICSGPIKFDEITAEAITVEWGPPKDDGGSEVTNY 19782 Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + R T W+ V + + L + Y+ R+ A N+ G+ E L SD Sbjct: 19783 FLEKRHSTANKWVTVASA-IQKNSMRVTRLHDGTEYIFRVCAENKYGIGEFLRSD 19836 Score = 171 bits (416), Expect = 2e-40 Identities = 186/785 (23%), Positives = 303/785 (38%), Gaps = 72/785 (9%) Query: 1358 YKLRLENNCGHADVE---MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +++ +NN G + V + + PPG PN +++ S+ + W+ P+ G S I+ Sbjct: 27464 FRVYAQNNAGMSPVSEQSKHKLAISPVDPPGTPNCIDVTRDSVTLQWEPPKRDGGSRIVA 27523 Query: 1415 YVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471 Y VE ++ W+ ++++ Q ++ L + FR A N V +S S+++ Y Sbjct: 27524 YSVERRQ-GRARWLRCNFIDVSECQFTVTGLAAGDRFEFRVIARNAVGTVSPPSQSSGYI 27582 Query: 1472 KVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK---KLKTAKA 1527 E+ I P +E + K++T + E+I+L+C G P P+VTWY+DGK K+ Sbjct: 27583 MTKDESVI--PQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDIT 27640 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 T Y A N G + +V +Q P E + + Sbjct: 27641 TVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQDTPG---PPEGPLRFTNIS 27697 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN------ITTKEKTSVIRIKELKRSHSS 1641 E A + PP N + +E + +T+K + +L + + Sbjct: 27698 AE---KATLWWSPPENDGCAAISNYVIEKRETSRISWALVTSKCEACSFNATKLIKGNEY 27754 Query: 1642 KYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 ++ + A N G S + Y P P P ++ S+T+ W P DGG Sbjct: 27755 QFRVSAVNKFGVGKPLESDPIIAQMQYTVPDAPGTPDCTH-VTGNSITLCWTRPRHDGGN 27813 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE- 1754 E+ +Y +E+ E + RW+KV+ E + + L E EY FRV+A+N G A Sbjct: 27814 EIKQYILERREKKSLRWVKVSAKRPITELRHRVTNLTEGNEYEFRVMAENGAGIGPASGI 27873 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813 S + PS SV + W +GG II Y +E+ K ++W Sbjct: 27874 SRLFKCREPTSAPSAPTLVKVIDSTKT-SVTLAWTKPVFDGGLEIIGYIIEMCKASLEEW 27932 Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 R+ +L Y+FR+ A N G ++ I Q + Sbjct: 27933 HRVNNQTCIQTHYRVTELESGEEYKFRVCAVNGAGKG-EFSETPHIV---------QAVD 27982 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI---------VTVGGSV 1922 + S K T NGG+ + K V +WTK + + Sbjct: 27983 RLTSPEIDIDADFKQTHIVKNGGTVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTF 28042 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 IEN D + +S EN G T + V P PP PL + V Sbjct: 28043 STLTIENCTRYDAGKYTLSLENNSGRKTITLTVKV-----LDTPGPP-GPLSFKDVTRGA 28096 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 + W P DGGA + Y + R+ ++ W EV + + + +L Y R+ Sbjct: 28097 LTLMWDAPSNDGGARVHHYIVEKREASRLSWQEVSERCTRQI-LRVINLDIGVAYFFRVT 28155 Query: 2043 ARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDA 2101 A N+ G EP E EP +I A EEP + W++ EH+ + Sbjct: 28156 AENQYGKGEPYEMTEP--II------ATEEPASPKRLDVIDTTSTTASLVWMKPEHDGGS 28207 Query: 2102 DIRSY 2106 I Y Sbjct: 28208 RITGY 28212 Score = 169 bits (412), Expect = 5e-40 Identities = 192/884 (21%), Positives = 354/884 (40%), Gaps = 80/884 (9%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283 ++TW K +S++E ++ L ++ + I++ T D +Y ++ +++ + V V Sbjct: 17607 EITWSKGESILERDKRTMLTNNFPVVQMRIKEATRADHGKYVLKAVNEAGEASATITVNV 17666 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH----TKPSID 1339 ++ P + + Y K + +V + A P+ N + + I++ C+ T I Sbjct: 17667 LDRPGHCQNLKMTYVTKN----SCMVSWDA-PEDNGGSEITNYIVE-CREPSIRTWAMIS 17720 Query: 1340 SKSASLTIK-KVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKP---NILEI 1392 S + +K K+ ++++ EN CG + + + +D PG+P ++ +I Sbjct: 17721 SDCTNRMVKAKLMENHEYLFRVSAENKCGPGPATETKTPILAIDPLQKPGEPENFHVGDI 17780 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450 + + + W +P+ G S + Y +E + D W + + +T + N Y+ Sbjct: 17781 GKNFVFLKWRKPDYDGGSPNLGYYLERKAKDAEAWEKLHEGVLKETFFMVDKCVENHIYQ 17840 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVP 1509 FR + N+ S T++ V+KE +IQ P ++ K + I + E + L G P Sbjct: 17841 FRVQSTNDGGESAWVSTSDI--VVKE-EIQKPVLDMKFVGTIVVKAGESVRLEAGLRGKP 17897 Query: 1510 QPKVTWYRD---GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 QP VTW +D G + + T + Y A N G V Sbjct: 17898 QPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVT 17957 Query: 1567 IQQ--KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + PV + I K W G I K + Y+ + Sbjct: 17958 VLDIPGPVRDMKISGISTD-KCRVAWDPPEDDGGCEVDSYIIEKCETRRMVWSTYSASLV 18016 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKV-YDKPSKPEGPVIMREIS 1679 T+ + L + + + A N GT S + K Y++P P+ P + + I Sbjct: 18017 --TNYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPIIAKTQYNRPGPPDAPEVTK-IG 18073 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 ++ +T+ W PP +DGG +T Y +E+ E RW+ V + L N +Y F Sbjct: 18074 KDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPVTKSPISERRMKVTNLIPNHDYQF 18133 Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 RV A+N VG E + S PI K ++ P S+ ++W +GG+P Sbjct: 18134 RVKAENEVGLGEPSKASRPITAKDPIEPPGPPGSLKVVDSTKT-SITLSWAKPVYDGGAP 18192 Query: 1799 IIDYKVEIK-------------QEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 +I Y VE++ +EG KK I L Y+FR+ A+N+ Sbjct: 18193 VIGYLVEMRDKVEMEGEQVRDPEEGWKKCNTSGQLVLTEYTISNLDERQEYEFRVSAQNQ 18252 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 +G P D ++ + P + S + ++++ G PI F Sbjct: 18253 VGMGRPANVKDAVSPKEVHEHP----EIDLDASLRKGLSVR-------AGCPIR----LF 18297 Query: 1905 KTVKGKSWTKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVG-----VSLPTESQ 1955 T++G+ K+ + V + ++ I ++ S+ G +S P+ + Sbjct: 18298 ATIRGRPAPKVTWKRIGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSGEK 18357 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 +V + P L+ + +W PE DGG+P+L Y + R+V + W Sbjct: 18358 AVFVRVKVLDTPGPVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRKTWTN 18417 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 D+ F I +L+ Y R+ A N+ G+ P +S + + Sbjct: 18418 CTN-DLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSY 18460 Score = 169 bits (412), Expect = 5e-40 Identities = 204/915 (22%), Positives = 353/915 (38%), Gaps = 58/915 (6%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKK------KSVIEDTEKFTL 1244 E P L + ++V + + V I +V WYK+ ++ I+ TE +TL Sbjct: 20408 EVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTL 20467 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 + +I +CT D +Y L + K T + V VV+ P V+ + K Sbjct: 20468 V--------VIPECTRYDAGKYVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHS 20519 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 + + +I+ + + ++ + + + S I +E +++ Sbjct: 20520 ITLQWEIPLIDGGSKIKNYIIEKREATRKAYSVITTNWQKCSYKIPDLEEAAEYYFRVSA 20579 Query: 1363 ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 EN G A+ + PS P + ++ + + W +P++ G S I YV+E Sbjct: 20580 ENEMGIGEPAETPDPIRASQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVIEA 20639 Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 Q D+ +W V I L N+ Y FR +AVN S SE E V+ + + Sbjct: 20640 QLKDSDQWAHVTTIKALDYIATELVENAEYVFRIFAVNS---SGRSEPRESRPVVIKEQT 20696 Query: 1480 QSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXX 1535 +P + K + + +++++ G P+P V W ++ ++LK T + EN Sbjct: 20697 TAPEFDLRSIYQKTVVAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASS 20756 Query: 1536 X---XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ---KPVITISNEDIKQKHKVGDE 1589 Y N G V + V + P I +++ + V Sbjct: 20757 TILNINEIKRKDGGQYSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDY-VLIS 20815 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 W G+P I + E T T + L ++ ++A N Sbjct: 20816 WEAPENDGGVPINNYIVEMRETTGTSWMELAATVIRTT--FKAARLTTGIEYQFRVKAQN 20873 Query: 1650 TAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 G TS V +D P +P P I+ +++++TI W P DGG + Y IE Sbjct: 20874 RYGVGPYITSGPVVAAYPFDVPGQPGIPQIV-AFTKDAMTISWNEPSSDGGSPILGYHIE 20932 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + E ++ W +++ + L + Y FRVIA+N G S+A S+P + AL Sbjct: 20933 RKEKNSILWQRISKAVVVGNMFKSSGLMDGIAYEFRVIAENLAGLSKA--SKPSEMTYAL 20990 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXX 1823 D P I V + W E +GG I Y VE ++ +W Sbjct: 20991 D-PVDPPSQPVALNITRHEVTLQWTKPEGDGGFSITGYTVEKRELPNGRWLKANFSNILE 21049 Query: 1824 AR--IQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 + L+ + +Y+FR+ ARN G S P + I + P + S Sbjct: 21050 TNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVV 21109 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN--IKEKDEIIF 1938 + G PI + I+ K K T + + C+ N +D + Sbjct: 21110 KAGDIFKLDAHVTGRPIPS-IVWTKDGKELEDTAKMEIKTLDFYSCLINKDSLRRDGGAY 21168 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 ++A N G + + V L++ P PP PL + + + SW P DGG + Sbjct: 21169 TLTASNPGGFAKFVFNVKV-LDR----PGPPEGPLHVTDMTVEKCVLSWLPPLHDGGGKI 21223 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 Y I R+ ++ W V D+ ++ + L + + Y+ R+ A N+ G+ EPLES+ Sbjct: 21224 EYYIIQRRETSRLTWTNVA-TDLQVNRYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPA 21282 Query: 2059 FKVIPGEGSHADEEP 2073 P S + P Sbjct: 21283 VATNPYVPSDPPQAP 21297 Score = 167 bits (407), Expect = 2e-39 Identities = 159/657 (24%), Positives = 286/657 (43%), Gaps = 38/657 (5%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 ++W++ G E+ S +++ DG+ L + + +D G Y+C E G + + L ++ Sbjct: 30197 IKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQ 30256 Query: 1193 -EPSINFTLRLPEFILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 P + L E T L V I + W+ K + +E + + Sbjct: 30257 AAPQFHPGFPLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESY 30316 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L+IR V L K T V VE K + E + ++++ Sbjct: 30317 THLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLPEGPVVVDALLKSSVIIS 30376 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVEN--TDAGIY-KLRLEN 1364 ++ P+ + ++ + I++K + + + S + S T +V N +G Y ++ +N Sbjct: 30377 WKP-PKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQN 30435 Query: 1365 NCGHAD-VEM-NVTIL----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 G ++ +E+ +V I+ +KP P +P + + S + W P + G + I Y +E Sbjct: 30436 QYGISESLEIPSVVIIKSPFEKPGVPQRPFVSSVTKDSCVVSWKPPTSDGGAKIKNYFLE 30495 Query: 1419 YQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E +WI+V I +T + + L Y FR N SD SE +E + Sbjct: 30496 KREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSD 30555 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE------ 1530 T +++P + L+++ + + G P+P V WY++GK++ A + Sbjct: 30556 TALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKG 30615 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV-G 1587 Y+ A N G + TS + ++ K + + + + H + G Sbjct: 30616 GYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRG 30675 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN--ITTKEKTSVIRIKELKRSHSSKYTI 1645 + + I G P P V W K G ++ N+ Y+ I T+ TS++ +K ++R S Y I Sbjct: 30676 EVVTIKIPISGKPDPVVTWQK-GQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYII 30734 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 A N G V L V D P P+ V + +I R+++T+ W P +DGG E+ Y IEK Sbjct: 30735 CAKNRFGMDKQTVELDVADVPDPPK-DVKVSDIGRDTLTLTWSPG-NDGGSEIINYIIEK 30792 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761 +RWI+VA Y + L +Y FRVIA+N G S+ + ++P+ K Sbjct: 30793 CPTTGDRWIRVAQTSE--SQYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDPVTTK 30847 Score = 166 bits (404), Expect = 5e-39 Identities = 167/760 (21%), Positives = 292/760 (38%), Gaps = 42/760 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284 +TW+K + ++ ++ ++ L + C D +Y L + T + V+V+ Sbjct: 14135 ITWHKDGNEMKADDRTFFRAEYTSCHLEVPSCLHADAGQYKVTLENRNGATSGTINVKVI 14194 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLV-DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 P D K V+ DY P +++ + + + K Sbjct: 14195 GLPGPCKDIVASEITKSSCKVSWEPPDYDG-GSPILHYVLQRREAGRRTYVKVMSGENKL 14253 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSI 1397 S +K + +++R N G + +E+ ++ +P PP S S+ Sbjct: 14254 SWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPPVDVETHNPTSESV 14313 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 + W P G S I+ Y++E + + + +++ L Y+FR A Sbjct: 14314 TLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKGLTHEKQYQFRVRA 14373 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVT 1514 N +SD S +T K T + L++ + + E+I L G P P++T Sbjct: 14374 ENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKRGEEIRLDANISGFPYPQIT 14433 Query: 1515 WYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 W R+ + + K E K A + E + ++K Sbjct: 14434 WMRNNATIWPEPLKKRPERPIKKKKEKEEKKEEGAEKKEADAEKKEEDKEAKEEDKEKK- 14492 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIR 1631 E+ K+K K +E PE ++ + N+ I +K K S I Sbjct: 14493 -EEKKEEEKEKEKE---------VEEPEEPEEEYHPSLNE-----RLTIESKRKGESYII 14537 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 IK+ R +TI+ N GT+S + + D P P EI + S+ +W PPL Sbjct: 14538 IKDTIRGDHGVFTIKVENDHGTASASCEVNILDTPGPPVN-FKFEEIRKNSILCKWDPPL 14596 Query: 1692 DDGGLELTKYAIEKHEPDNNR--WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 DDGG E+ Y +E+ + WI V + R + + + KL E EY+FRV A+N G Sbjct: 14597 DDGGSEILNYILERKDNSKAELGWITVTSILRGCK-FLVPKLIEGKEYLFRVTAENKYGP 14655 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808 + ++P++ + D P + S+ +TW NG S I Y VE ++ Sbjct: 14656 GKPCITKPVIARNPFDPPDAPEKPEIKD-VTASSMCVTWLEPNDNG-SAIEGYWVEKREI 14713 Query: 1809 EGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 W I + L TY FR+ A N G + T + PP Sbjct: 14714 NSTHWARVNRTMVPDLEINVEGLLEGLTYIFRVCAENIAGPGKFSPPSEPKTAQAPIMPP 14773 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 P +V +++ S+ ++W P NGG+ + Y ++ K W++ Sbjct: 14774 GPPIPRIV-DTSDYSIDIEWDPPADNGGAEVFGYHVDKLVAGTKDWSRATERPHKTRTFT 14832 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 + ++E + I R+ A N G P + +V + A VP Sbjct: 14833 VYGVREGAKYIVRVVAINCAGEGEPGLTDAVIVRNPAEVP 14872 Score = 166 bits (404), Expect = 5e-39 Identities = 208/959 (21%), Positives = 363/959 (37%), Gaps = 66/959 (6%) Query: 1138 RWFKDGSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195 +W++ + S +T KK ++ + GE+S G+ + VE P Sbjct: 29020 QWYRATQKTLTSTQYTVTGLASNKKYSFRVAAVNAMGTGEFS--EGSMETAPSERVEIPD 29077 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LI 1254 I L + + + A L V + V ++K + D + I + T LI Sbjct: 29078 IELPDELKKTVCIRAGNTLRLNVTVSGRPAPVITWRKTGI--DLQSRGFIDTTENSTSLI 29135 Query: 1255 IRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 + K D +YT + K T + V++ + P + K +T V Sbjct: 29136 VEKVHRYDAGKYTIEAENPSGKKTITILVKIYDTPGPCGAVNVKDYTKESVVITWDVPTI 29195 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG---HA 1369 + +I+ + + + + K I +E +++ EN G Sbjct: 29196 DGGAHINNYIIEKREASMKSYKTVTTECKKTLYRITGLEEGTQYFFRVLPENIYGVGEPC 29255 Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 + V + + PS P +++ S++ + W++P + G S + +V+E + T W++ Sbjct: 29256 ETPEPVLVCEVPSVPQDLYLIDTTKSTVILGWEKPLHDGGSRLSGFVIEACKTGTDRWMN 29315 Query: 1430 VKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK- 1486 V ++ + Q +I +L N Y FR A N +S+ + + ++ ++ + Sbjct: 29316 VAHVKSSVLQHTIVSLTENEQYLFRIRAENSRGVSEPRDLMTPVTIQEQREMPKIDLTGI 29375 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXXXXXXX 1541 P K + + I L G P P +W G K+K T Sbjct: 29376 PQKIVNVPAGKPIVLNIPIKGRPAPVCSWSFGGVKMKDKLDRIKIETTAKFTKLTVRETT 29435 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y N G V I KP + + I++ D VT E P Sbjct: 29436 IDDTGDYTLNVKNVSGTATEVIRVIILDKPGVPVGPMKIEEV----DATSVTCSWE---P 29488 Query: 1602 PEVIWYKN--GNKLENDKEYN---ITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGT- 1653 P+ N G +E + ++ E + V + L + + A+N G Sbjct: 29489 PQKDGGANVSGYIVEQRDAHRPGWMSVSESVTRPVFKFTRLVEGTEYVFRVAATNRFGIG 29548 Query: 1654 ----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 S V V P P P I+ ++S + +T+ W PP D+GG + Y IE+ E Sbjct: 29549 GFLQSEVVECKSVKTVPGAPSTPEIL-DVSHDGMTLTWTPPEDNGGSTIAGYIIERKEAG 29607 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768 ++RW+ + + Y L E EY +RV A N G + + S+P + ++ P Sbjct: 29608 SDRWLSINKNPVTMTRYRATGLIEGLEYEYRVTAINSRGTGKPSANSKPTIAMDPIEPPG 29667 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXAR-- 1825 SV + W P E+ GG+ + Y +E+ K + +W Sbjct: 29668 IPLNPRVTDTT-RTSVSLAWSPPEEEGGAAVTGYLIEMQKVDQVEWTKCNTTPTKICEYT 29726 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + + Y+FR+ A N G P + + + L P + E Sbjct: 29727 LTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEKIYQEGYV------ 29780 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-HEHCIENIKEKDEIIFRISAEN 1944 GG + I+ K + WTK G + H I +E+ E++ + + + Sbjct: 29781 ----VRQGGVIRLSVPIKGKPLPTCKWTK---EGRDISHRAMIATSEERTELVIKEAHRD 29833 Query: 1945 TVGV-SLPTESQSVRLEKHATV-----PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 G L E++ R + V P PP PLE + + V SW P DGG+ + Sbjct: 29834 DTGTYDLVLENKCGRKAVYIKVKVIGRPDPPEGPLEFDDIQARSVRVSWRPPSDDGGSDI 29893 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 GY + R+V K W V V+T ++ L EN Y +I A N+ G+S+ L+SDE Sbjct: 29894 FGYIVERREVPKAAWYTVDSRVVDT-SLVVKGLKENVEYHFKITAENQFGISKSLKSDE 29951 Score = 165 bits (400), Expect = 2e-38 Identities = 184/716 (25%), Positives = 297/716 (41%), Gaps = 61/716 (8%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436 D P P KP I ++ +SS+ + W EP + G S I Y VE +EI++T W V + Sbjct: 14671 DPPDAPEKPEIKDVTASSMCVTWLEPNDNG-SAIEGYWVEKREINSTHWARVNRTMVPDL 14729 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + +++ L +Y FR A N S +E + I P P T++ + Sbjct: 14730 EINVEGLLEGLTYIFRVCAENIAGPGKFSPPSE--PKTAQAPIMPPGPPIPRIVDTSDYS 14787 Query: 1497 EDIELT--CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXY-- 1548 DIE GG +V Y K + K AT Y Sbjct: 14788 IDIEWDPPADNGGA---EVFGYHVDKLVAGTKDWSRATERPHKTRTFTVYGVREGAKYIV 14844 Query: 1549 KCIAFNDHGEVE---TSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPP 1601 + +A N GE E T V+ ++ + + DI ++ V G+ + A + G PP Sbjct: 14845 RVVAINCAGEGEPGLTDAVI-VRNPAEVPVIELDISVRNGVVVRAGEMLRIPAHVTGRPP 14903 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P + W K+ LE D+ + + S + IK KRS KY I+A+N +G S ++ Sbjct: 14904 PSLKWTKDDGDLEKDR-MEVEEAGQDSTVVIKTTKRSDHGKYQIQAANPSGIKSAWTRVE 14962 Query: 1662 VYDKPSKPEGPVIMRE---ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 V D P GPV+ + ++R+ + + W P DDGG ++T + IE+ EP + W + Sbjct: 14963 VMDVP----GPVLDLKPVVVTRKLMMLNWSDPDDDGGSDVTGFIIERREPKMHTWRQ--P 15016 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXX 1776 ++ I + E EY+FRV+A+N G ++ PI A+D P Sbjct: 15017 IETPSSKCEIVGIIEGQEYIFRVVAKNKYGCGPPVDLGPI---RAVDPQGPPTSPEKFHY 15073 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI---QKLSINT 1833 SV I W P +GGSPII Y +E K++ + +I L Sbjct: 15074 TERTKSSVTIEWRPPRNDGGSPIIGYIIEKKRQDQPAFQRVNPELCTVQIMTVDNLDELH 15133 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 Y+FR A N G S P + + + P + + P Sbjct: 15134 MYEFRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVT 15193 Query: 1894 GSPI-------TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946 G P+ + +IE T K TK + S + I + D+ + ++A N + Sbjct: 15194 GLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDKGTYTVTASNRL 15253 Query: 1947 GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 G T S SV +E P+PP + + + + SW P GG+ L Y + ++ Sbjct: 15254 G----TLSHSVTVEV-LDRPTPP-RNVAVSSIKAESCNLSWDAPLDIGGSELTNYIVEMK 15307 Query: 2007 DVT-----KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 D+ K W++V K + ++ + +L Y R+ A N+ G+SE E++E Sbjct: 15308 DLNVEDPEKAEWVQVTK-SIIEKRYGVWNLVTGGNYKFRVKAENKYGISEACETEE 15362 Score = 163 bits (397), Expect = 4e-38 Identities = 132/460 (28%), Positives = 212/460 (46%), Gaps = 30/460 (6%) Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMR- 1676 +T + S I I ++ + + ++A N AG S+ +K+ D +P P+ + Sbjct: 12957 VTKPHERSAI-INDVIENKEYIFRVKAENKAGIGKPSAATNPVKIMDPIERPSPPLNLTH 13015 Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNEN 1734 E +++S + W+ PL +GG +T Y IE+ E ++W++ A + D+ Y + L Sbjct: 13016 SEQTKDSCLLTWETPLKNGGTAITGYIIERCEEGTDKWLRCNARLCPDL-LYRMSGLKFG 13074 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 +Y +RVIA+N G S+ IV D P D V++ P+ + Sbjct: 13075 KKYSYRVIAENAAGQSDPSN---IVGPVLADDPHYAPTLDLSAFKDGLEVFV---PNPLS 13128 Query: 1795 GGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY--ARNEIGT-SLPY 1851 PI Y + KW R+ ++ +T + I R + GT SL Sbjct: 13129 IRVPITGYPIPTA----KWTFGENALTAGDRVSMVTKSTFTELVITPSVRADKGTYSLTL 13184 Query: 1852 TSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 +D G+ + PS P++ V+E T + V L W PE +GGSPIT Y +E + V Sbjct: 13185 ENDVASVSGEIEVNVIASPSAPKDLKVAEVTRKHVHLMWEAPEHDGGSPITGYQVEKREV 13244 Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVP 1966 K+W K+++ G E+ + ++ E E +FR+ A N G P + V + ATVP Sbjct: 13245 SRKTWVKVMS-GLQDQEYTVTDVVEGKEYLFRVIACNKCGPGEPAYIEDPVNVSSPATVP 13303 Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 PP L+ R ++ + SW P+WDGG P+ GY + W G + LKF Sbjct: 13304 DPP-ENLKWRDKSASKIFLSWEPPKWDGGTPIKGYIVDKCQRGTDKWEPCGD-PMPELKF 13361 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLES-DEPFKVIPGE 2065 + L E Y R+ A N++G S+P +S DE V P E Sbjct: 13362 EVTGLIEGQWYAYRVRALNKLGASKPCKSTDEILAVDPKE 13401 Score = 163 bits (397), Expect = 4e-38 Identities = 127/468 (27%), Positives = 204/468 (43%), Gaps = 18/468 (3%) Query: 1594 AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 A I G P P+V W + G ++N + ++ + + + I E R S KY++ SN +G Sbjct: 18298 ATIRGRPAPKVTWKRIG--VDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSG 18355 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 +V V +KV D P P G + +I++ S + W PP +DGG + Y +EK E D Sbjct: 18356 EKAVFVRVKVLDTPG-PVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRKT 18414 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772 W + D ++ I L EY FRV+A N G +S + T Sbjct: 18415 WTNCTN-DLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATDPKSEPDPPK 18473 Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829 I S + W ++GGS I Y VE +Q+G+ KW + L Sbjct: 18474 KMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQDGQPEDKWTSYSVVKDLTIVVAGL 18533 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 NT Y+FR+ ARN IG SL ++ + + L P + VV+ + + Sbjct: 18534 KENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIVSDVVTARAGSKLIVDALV- 18592 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 S +P+T + + S ++ + ++++ KD + +SAEN S Sbjct: 18593 -SGKPAPVTKWKRGSDDIV-TSDRVVIQKTPTTSLLMVKDVTRKDSGYYSLSAEN----S 18646 Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 +Q +R+ +P PP PL+I V + +W TP DGG+ + Y + DVT Sbjct: 18647 TAKVNQIIRIII-MDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSNITNYIVEKCDVT 18705 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + W V V + L+ Y R+ A N G+SEP+ S++ Sbjct: 18706 RGDW--VTAVSCTKTSCRVGKLTCGKEYGFRVRAENRFGISEPIYSEK 18751 Score = 163 bits (396), Expect = 5e-38 Identities = 172/767 (22%), Positives = 300/767 (39%), Gaps = 50/767 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP FS+K K G + L+C+ I+W EI+ N + + Sbjct: 6842 VPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTENT--- 6898 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 C+ LK+ +K GTY AVN G A L +K EPP + + + G + Sbjct: 6899 CT-LKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVK----EPPSFVTTPQPVEALPGTT 6953 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V +A V G+ + W + +K + ++ GDT + + K G YT + Sbjct: 6954 VTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGDTAILELHNIDK-SHAGEYTCQII 7012 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G + V+E F+ + + ++V+ ++ L +P + W++ Sbjct: 7013 NDAGKENCPVNLFVKEAAH-------FVKKLKNLSVEMGKSLILECTYAGSPKILVKWHK 7065 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + I S + L N D E +G Y C SN AG A V+I +E Sbjct: 7066 DGQEIYSSYKYNITTTESSCILECLNSDKEA-AGKYTCEVSNDAGHDICEAAVSI-LEPP 7123 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXX 986 F++ L+ E G V L+CQ T K W+ ++ ++ Sbjct: 7124 FFIESLEPM-EVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEFFKGIACLKL 7182 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040 D+G C ++ +S L V++ T P F +K+ E E + Sbjct: 7183 AKVAKSDIGEYTCKAENSIGSATSSCHLTVQDVKTPPSFPKKITSIMQIEGQPVQFECRV 7242 Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 S +V W +DGE ++ ++Y + L I + GEY+C+ + S Sbjct: 7243 AGSSPMEVSWLKDGEALR-SDSEYTMSFDDNSAVLNIAKGEMRHSGEYTCVATNSVGSAS 7301 Query: 1096 CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152 C A++T+ E PP +L V+ G+ E +T + V W KD +I+ + Sbjct: 7302 CRAKLTLQEPRYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNY 7361 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 +++ L I D D+G YSC +VG C+ ++V+E I + + Sbjct: 7362 KISCVENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPPSFTKKPSTTI 7421 Query: 1209 PANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 + +E + L V WYK I ++ + + L I+K D Sbjct: 7422 EDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGT 7481 Query: 1266 YTCVLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 Y C + T +V V + PP + + G +TL + P +W Sbjct: 7482 YVCKATNEAGTASFEVSVHITAQKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQW 7541 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 + + + + +TK + +A+L + +V TD+G Y + N G+ Sbjct: 7542 MKDRRELSSSANTKITFVDGTATLEMTRVSKTDSGDYLCKATNEAGN 7588 Score = 161 bits (390), Expect = 3e-37 Identities = 124/428 (28%), Positives = 191/428 (44%), Gaps = 18/428 (4%) Query: 1642 KYTIEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 ++ + A N AG S E+T + D P PV + I+R VT++W P DGG Sbjct: 20966 EFRVIAENLAGLSKASKPSEMTYAL-DPVDPPSQPVALN-ITRHEVTLQWTKPEGDGGFS 21023 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGF--SEALE 1754 +T Y +EK E N RW+K A+ +ET + + L E+ Y FRV+A+N G + Sbjct: 21024 ITGYTVEKRELPNGRWLK-ANFSNILETNFTVSGLTEDVSYEFRVLARNSAGAVSKPSKP 21082 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK 1814 SE IV + ++ P + ++ I + G PI + ++GK+ + Sbjct: 21083 SEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTG-RPIPS--IVWTKDGKELE 21139 Query: 1815 XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV- 1873 IN R + S P + K L P P + Sbjct: 21140 DTAKMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGGFAKFVFNVKVLDRPGPPEGPLH 21199 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 V++ T L W P +GG I YII+ + +WT + T V+ + + + + Sbjct: 21200 VTDMTVEKCVLSWLPPLHDGGGKIEYYIIQRRETSRLTWTNVAT-DLQVNRYKVTKLLKG 21258 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPS-PPTAPLEIRMVGSNIVMTSWGTPEW 1992 +E IFR+ A N GV P ES+ + + VPS PP AP E+ + + ++ WG PE+ Sbjct: 21259 NEYIFRVMAVNKYGVGEPLESEPA-VATNPYVPSDPPQAP-EVTAITKDSMVVCWGHPEY 21316 Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 +GG+ + Y I RD T W++ K V L+F + L+ H Y RI A N GLS P Sbjct: 21317 NGGSSINTYIIERRDKTGLRWVKCNKRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAP 21376 Query: 2053 LESDEPFK 2060 S +K Sbjct: 21377 SPSSPFYK 21384 Score = 159 bits (387), Expect = 6e-37 Identities = 233/1100 (21%), Positives = 439/1100 (39%), Gaps = 81/1100 (7%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 W+ G I + + + I+ +H L + NV K G Y+ V ++ S + + Sbjct: 2161 WMKNGLPISASDRVHIVIDKLVHK----LLVENVNKDDAGIYSFVVPIQDISTSGKLTV- 2215 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783 + ++I LK + +G +L A++ + + W +N+K + A + + Sbjct: 2216 ------QSIEIISHLKDVHSIEGTKAVLEAKISASDVAAVKWYQNDKLLVASERIQMVAK 2269 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G T +L DEG Y + G ET+ +TVE+ + I ++ Sbjct: 2270 G-TKQRLVLNRSFGSDEGQYKMAV----GRVETTCNLTVEKVS--------IIKHMEDCV 2316 Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 E + ++ + + W N+ + G++ L I N + + G Sbjct: 2317 CTETQNVTFEVELSHTGIDAY-WTFKNQPLKAGPKYKIESKGKHYSLTIINAMKD-EEGL 2374 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYH 962 Y + +AG+ A++T+ + H E +T ++EC+ ++ S KW Sbjct: 2375 Y----AFAAGEKISSAKLTVSGGAINRPLH---DVTVAESQTAVMECEVANPTSEGKWLK 2427 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK 1022 + + D D+G V + +TS L V+ + + Sbjct: 2428 DGHSVDFSDIVRSEDIDAVRRLIFVITRPQDIGEYTYQVANSKTSANLRVEAV--KIKKT 2485 Query: 1023 LQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081 L++ V E A+ +E+ + W ++G I+P +KY+ G + L I+N + Sbjct: 2486 LKNQTVTETQEAVFSLELTHLDVKGSQWIKNGVEIEPS-DKYEITVDGLVHTLKIKNCNS 2544 Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141 DE Y L S A + V + +I+ + ++ A+FE+ L+ D V+W Sbjct: 2545 QDESVYGFKLGKLSANARLNVETI--KIVKKPKDVTSLVNGTASFELSLSHDDIPVKWMF 2602 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201 E++ S ++Q+ + K KL I + + + GEY+ VG+ +C+A L VE + L+ Sbjct: 2603 KNQELKPSANVQIMSERKAHKLVIQNVEESNDGEYTAVVGHLQCSAYLHVESLRVTKPLK 2662 Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 E VP A E+ + TW K IE +EKF ++ K L I + D Sbjct: 2663 NLE---VPETHVATFECEVSHFNVPSTWLKNGVEIEMSEKFRIVVQGKLHQLKIMNTSRD 2719 Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 D EYT V + K + L V V + D + + +VT V+Y+ +W Sbjct: 2720 DSAEYTFVCGNDKVSATLTVSPVLITSMLKDLNAQEKDTITFEVT--VNYEGITY---KW 2774 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + N I+ + S SLTI+ V D G YK G A+ + + + Sbjct: 2775 LKNGVEIRSSDRCQTRTKQLSHSLTIRNVHFGDVGDYKFV----AGSAETAAKLFVEARV 2830 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSI 1440 K +I +I + E E + + + ++ + QE++ +E V + I Sbjct: 2831 IEFTK-HIKDIKVTEKKKAVFECELSEPNVQVTWMKDGQELELSERYKVSTERHVHRLMI 2889 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED-I 1499 Q ++ + + + A + V ++ + + ++ + + + +EK E NED I Sbjct: 2890 QTVRMSDAGEYSVVAGSSVSKANLTVEGKDVRISEPAEKEITVLEKQRSTFEFEVNEDDI 2949 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 E + GV ++ + D ++ A +R Y IA + V Sbjct: 2950 EGRWLRNGV---EIQFSVD-QRFNYAIIRKIHRLTITETYRSDAGE--YTFIAGKNRSIV 3003 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 V I + P I + + + G + + GIP P+V WYKN L + + Sbjct: 3004 TLH--VNIPEPPQIIRHMQPLSVE--AGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKC 3059 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEG-----P 1672 + + + E+ +++Y EA N G TSS + ++V + S G P Sbjct: 3060 KFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPP 3119 Query: 1673 VIMREI----SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 V++ I + E + ++ + L +T Y +K E + +V+ D + + I Sbjct: 3120 VVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDK-EIKQSDIFRVSQFDENCQLE-I 3177 Query: 1729 QKLNENCEYMFRVIAQNPVG 1748 ++ E + +A+N G Sbjct: 3178 TRVYPEDEGEYTCVARNSAG 3197 Score = 155 bits (376), Expect = 1e-35 Identities = 182/801 (22%), Positives = 313/801 (39%), Gaps = 76/801 (9%) Query: 1349 KVENTDAGI---YKLRLENNCGHADVEMN---VTILDKPSPPGKPNILEIDSSSINICWD 1402 KV N +AG+ +K+ EN G + + V +D PP + +I +SI++ W Sbjct: 26365 KVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACEPPNSVRVTDITKNSISLAWQ 26424 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV- 1459 +P G S I Y++E ++ W ++ N+T T+ ++ L N SY FR A N V Sbjct: 26425 KPSYDGGSKITGYLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRVMAKNAVG 26484 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 +S+ SE + +P V+ P L + + ++L PQP + WY Sbjct: 26485 SVSNPSEIVGPVTCVDT--YGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIEWY 26542 Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXX---XXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +DGK+L++ A+ + N Y+ N G + V +Q KP Sbjct: 26543 KDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLGSAYAAVRVLVQDKPG 26602 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPE----VIWYKNGNKLENDKEY--NITTKEK 1626 +I+ K D T I PP + ++ + K E + I+ K + Sbjct: 26603 PPAG--EIQFKKITAD----TMTIMWDPPADEGGAMVTHYIVEKRETSRIMWSIISEKLQ 26656 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRE 1681 ++ + L + + + + N G S + + PS+P P + I+R Sbjct: 26657 DCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRPVIAQNSFVHPSQPSKPQVTM-ITRS 26715 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFR 1740 ++T+ W+ P DGG ++ Y +EK E + +W KV D RD + L E EY +R Sbjct: 26716 TMTVVWERPSLDGGSDIDGYYLEKREKKSLQWFKVIKDPIRDTRQK-VHNLTEGNEYQYR 26774 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT--WFPSEKNGGSP 1798 V A N G S+ + A D +D+ IT W +GGS Sbjct: 26775 VCAINKAGAGPY--SDVSIFYKAYDPIDPPSEPTKLRVVDSTKTSITLGWVKPVYDGGSE 26832 Query: 1799 IIDYKVEIK-QEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 I Y +E + + +W + L Y +R+ A N +GT Sbjct: 26833 ITSYVIEQRIADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIE-- 26890 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI-IEFKTVKGKSWT 1913 + P Q ++ + +++ T+ + G + I ++ + +W Sbjct: 26891 --------IVQPVQAKDILEEADVDLDISMS-TQYIAKAGRDVEIVIPLKGRPAPNVTWR 26941 Query: 1914 K-IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP----SP 1968 K + G + I N + +I + G L V K TV Sbjct: 26942 KGDKNISGDAR-YAIRNTEYSTTLIIPKVTRDDTGKYLLEIENGVGEPKTITVSVKVLDT 27000 Query: 1969 PTA--PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 P+A L ++ V + SW P DGG+P+ Y + +D + V NT + Sbjct: 27001 PSACNRLIVKNVTRGKLTLSWEPPYIDGGSPITNYVVEKKDAKMKAFTIVTNECANTT-Y 27059 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXX 2086 + LSE +Y R+ A NE G+ +P E+++P + A E PG ++ Sbjct: 27060 KVDGLSEEISYFFRVSAENEYGVGDPCETEQPVR--------ATEMPGAIKDLVLVDSTN 27111 Query: 2087 XXXXXXWLR-EHNMDADIRSY 2106 W + +H+ + I Y Sbjct: 27112 TSVSLAWTKPDHDGGSHINEY 27132 Score = 153 bits (370), Expect = 7e-35 Identities = 122/474 (25%), Positives = 197/474 (41%), Gaps = 22/474 (4%) Query: 1642 KYTIEASNTAGTSSVEVTLK--VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 ++ + A N G T + + P P G + ++R SV + W PP DGG +T Sbjct: 23129 EFRVYAENIVGIGKCSKTSEGCIARDPCDPPGTPVPVIVTRHSVKLRWTPPEYDGGSLVT 23188 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y +EK + RW+K + + + + L E+C+Y FRVIA+N G S + SE Sbjct: 23189 GYVVEKRDLPEGRWMKASFANILETEFTVTGLIEDCKYDFRVIARNGAG-SVSRPSESTG 23247 Query: 1760 IKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID---YKVEIKQEGKKWK 1814 TA D P I + T+ G PI +K +++ E Sbjct: 23248 SVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARA 23307 Query: 1815 XXXXXXXXXARIQKLSINTTY-QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 + K +I Q+ ++ N G+ + + + PP P Sbjct: 23308 EIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSK---SVSFNVRVLDRPGPPEGP--LT 23362 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 VS T+ +L W P +GGS I+ Y+I+ + +WT +V+ + + + Sbjct: 23363 VSGVTNEKCSLSWLPPRHDGGSSISYYVIQKRETSRLAWT-VVSGDCGATMFKVTKLLKG 23421 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 +E IFR+ A N GV P ES++V + P PP LEI + + + W PE D Sbjct: 23422 NEYIFRVMAVNKYGVGEPLESRAVIMRNPFVAPGPPQ-DLEITNISRDSMTVCWTRPESD 23480 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 GG ++GY + RD W + K V L+F + L+E+H Y R+ A N G+ +P Sbjct: 23481 GGNEIVGYIVEKRDRAGIRWTKCNKRRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQPS 23540 Query: 2054 ESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLRE-HNMDADIRSY 2106 + +K +PG+ T W R ++ DI+ Y Sbjct: 23541 QPTVYYK-----ACDPTFKPGQPTNAHLVDTTKNSVTVAWSRPIYDGGLDIQGY 23589 Score = 152 bits (368), Expect = 1e-34 Identities = 151/691 (21%), Positives = 288/691 (41%), Gaps = 29/691 (4%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-E 889 E P + R Q TV ++ RV P P W++N ++ S+ + + +++ E Sbjct: 1849 EAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPEDHVCE 1908 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVIL 948 LVI +V +E DS A N AG++S A + + ++V +F + L+ +Y E+ V Sbjct: 1909 LVIRDVLAE-DSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKEKDTMVTF 1967 Query: 949 ECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-- 1005 EC+T+ V KW N EI D + + + D C V D + Sbjct: 1968 ECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQDDAEYSCAVVDDDHI 2027 Query: 1006 -TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064 T+ L V+ E ++ L+ EV E E E++ E A+ W + + I P KY Sbjct: 2028 RTTARLYVEGAPLEIVKNLESVEVPETYSGEFECELSREDAEGTWYFENKEITPSL-KYV 2086 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124 R L +++ D+G+Y+ + D +A + + P ++ L + + +G+ A Sbjct: 2087 VSSRRGRHTLSVKDVRKEDQGKYTFKVGDLKTSATLKMKLRPVTLMQGLSDLTICEGDIA 2146 Query: 1125 TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 E+ ++ + W K+G I S+ + + ID KL + + + DDAG YS V Sbjct: 2147 QLEVRFSQENVEGTWMKNGLPISASDRVHIVIDKLVHKLLVENVNKDDAGIYSFVVPIQD 2206 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFT 1243 + + SI L + + T A L +I + V WY+ ++ +E+ Sbjct: 2207 ISTSGKLTVQSIEIISHLKDVHSI-EGTKAVLEAKISASDVAAVKWYQNDKLLVASERIQ 2265 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 +++ K+ L++ + D+ +Y + ++T L VE V I+ + + Sbjct: 2266 MVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKV----SIIKHMEDCVCTETQ 2321 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 +VT V+ + + W ++ +K K K SLTI + G+Y Sbjct: 2322 NVTFEVEL-SHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINAMKDEEGLYAFAAG 2380 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 A + ++ +++P + E ++ + P + G + V++ +I Sbjct: 2381 EKISSAKLTVSGGAINRPL--HDVTVAESQTAVMECEVANPTSEGKWLKDGHSVDFSDIV 2438 Query: 1424 TTEWISVKN-----ITKTQT------SIQNLKTNSSYRFRAYAVNE-VDISDASETTEYY 1471 +E I IT+ Q + N KT+++ R A + + + +ET E Sbjct: 2439 RSEDIDAVRRLIFVITRPQDIGEYTYQVANSKTSANLRVEAVKIKKTLKNQTVTETQEAV 2498 Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 ++ T + + + EP++ E+T Sbjct: 2499 FSLELTHLDVKGSQWIKNGVEIEPSDKYEIT 2529 Score = 151 bits (365), Expect = 3e-34 Identities = 122/484 (25%), Positives = 203/484 (41%), Gaps = 18/484 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 ++G P PE+ W + + + IT T + I+ + R KY + N++GT + Sbjct: 21520 VKGRPAPEIRWSREKGEPLDRASIEITPSFTT--LLIENVDRFDGGKYMLTVENSSGTKT 21577 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 + ++V D P P+ I +EI+++SV++ W PP+ DGG + Y +EK E + Sbjct: 21578 AFINVRVLDTPGAPQNLTI-KEITKDSVSLIWDPPVIDGGSRIRHYIVEKRESTRKAY-S 21635 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 + + ++ I L E Y FR++A+N G +E+ + + +P Sbjct: 21636 IVNASCPKTSWRIGDLQEGNLYFFRILAENEYGVGLPVETMEAIKISERPLPP---GKVT 21692 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTT 1834 + + SV ++W + +GGS I Y VE++ + KW A + L+ Sbjct: 21693 LKEVTSNSVTLSWEKPDHDGGSRITGYIVEMQGKNSDKWTQVMTVKVTEAVVVGLTQGEE 21752 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y FRI A NE G S P + + P+ F + S LK P Sbjct: 21753 YSFRISATNEKGISDPRPLSVPVIAKDVVIAPAFKLLF-STFSVLAGDDLKIDVPYV--A 21809 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI-IFRISAENTVGVSLPTE 1953 P + + + K T++ T H + + +D++ + I N+ G + Sbjct: 21810 QPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAG-EATAD 21868 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 + L+K P PPT P++I V ++ V SW PE++GG + Y + RD + T W Sbjct: 21869 INVIVLDK----PGPPTGPIKIEEVTADSVTLSWQPPEYEGGCSINNYIVEKRDTSTTNW 21924 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 V T R L Y RI A N G S + S+ P E H P Sbjct: 21925 QIVSATVARTTTKAAR-LKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIP 21983 Query: 2074 GEQT 2077 Q+ Sbjct: 21984 AVQS 21987 Score = 149 bits (361), Expect = 8e-34 Identities = 219/1096 (19%), Positives = 418/1096 (38%), Gaps = 86/1096 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P ++ ++Q V ++ CR++ P+P+ W G + + + D H+ C Sbjct: 1851 PKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWYWPED-HV-CE 1908 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I +V + V A+N GEAS L ++ K+ + L+ ++ ++++ Sbjct: 1909 -LVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQA--KQVVSFTQTLEDAYAKEKDTMV 1965 Query: 754 LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 P + W KNN + SD H +++L ++D+ Y+ + Sbjct: 1966 TFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVL-IINMQDDAEYSCAVVDD 2024 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 + I T+ + P E + + + V E + + ++R TWY N Sbjct: 2025 DHIRTTARLYVEGAPLE-------IVKNLESVEVPETYSGEFECELSREDAEG-TWYFEN 2076 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + I+PS + L + +V E D G Y + G A + + + VT Sbjct: 2077 KEITPSLKYVVSSRRGRHTLSVKDVRKE-DQGKY----TFKVGDLKTSATLKMKLRPVTL 2131 Query: 931 VKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 ++ L EG LE + S V W N IS D I+ + Sbjct: 2132 MQGL-SDLTICEGDIAQLEVRFSQENVEGTWMKNGLPISASDRVHIVIDKLVHKLLVENV 2190 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVV 1048 D G+ +V Q+ ST + E I L+D E A+LE +I+ S+ A V Sbjct: 2191 NKDDAGIYSFVVPIQDISTSGKLTVQSIEIISHLKDVHSIEGTKAVLEAKISASDVAAVK 2250 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W ++ +++ + + +G ++L + + DEG+Y + T +TV ++ Sbjct: 2251 WYQNDKLLVASE-RIQMVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKV--S 2307 Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 II +++ + TFE+EL+ W ++ ++ GK L I + Sbjct: 2308 IIKHMEDCVCTETQNVTFEVELSHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINA 2367 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228 D+ G Y+ G +A LTV +IN L + V + A + E+ + T + Sbjct: 2368 MKDEEGLYAFAAGEKISSAKLTVSGGAINRPL---HDVTVAESQTAVMECEVANPTSEGK 2424 Query: 1229 WYKKKSVIE--DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 W K ++ D + I V++ +I + D EYT + ++K++ L+VE V Sbjct: 2425 WLKDGHSVDFSDIVRSEDIDAVRRLIFVITR--PQDIGEYTYQVANSKTSANLRVEAV-- 2480 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 KI + + + ++ +WI N I+ + ++D +L Sbjct: 2481 --KIKKTLKNQTVTETQEAVFSLELTHLDVKGSQWIKNGVEIEPSDKYEITVDGLVHTLK 2538 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 IK + D +Y +L +A + + + I+ KP D +S+ Sbjct: 2539 IKNCNSQDESVYGFKLGKLSANARLNVETIKIVKKPK----------DVTSL-------- 2580 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 N T + + + +W+ K ++Q + +++ V E + + + Sbjct: 2581 --VNGTASFELSLSHDDIPVKWMFKNQELKPSANVQIMSERKAHKLVIQNVEESNDGEYT 2638 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + + ++S V KPLKN+ C P TW ++G +++ + Sbjct: 2639 AVVGHLQCSAYLHVESLRVTKPLKNLEVPETHVATFECEVSHFNVPS-TWLKNGVEIEMS 2697 Query: 1526 K----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 + Y + ND +V + V +IT +D+ Sbjct: 2698 EKFRIVVQGKLHQLKIMNTSRDDSAEYTFVCGND--KVSATLTV---SPVLITSMLKDLN 2752 Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 + K + VT EGI W KNG ++ + TK+ + + I+ + Sbjct: 2753 AQEKDTITFEVTVNYEGI---TYKWLKNGVEIRSSDRCQTRTKQLSHSLTIRNVHFGDVG 2809 Query: 1642 KYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEWKPPLDD 1693 Y A + + + V +V + K ++ + V E+S +V + W D Sbjct: 2810 DYKFVAGSAETAAKLFVEARVIEFTKHIKDIKVTEKKKAVFECELSEPNVQVTWMK--DG 2867 Query: 1694 GGLELT---KYAIEKH 1706 LEL+ K + E+H Sbjct: 2868 QELELSERYKVSTERH 2883 Score = 149 bits (361), Expect = 8e-34 Identities = 162/713 (22%), Positives = 280/713 (39%), Gaps = 45/713 (6%) Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-- 1431 ++ LD PPGKP+++ + +S+ + W P+ G + Y+VE E W+ Sbjct: 19903 SLVALDPIDPPGKPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMKANHV 19962 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 N+ ++ +L+ + FR A N IS SETTE E + + T++ +K+ Sbjct: 19963 NVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEMKD 20022 Query: 1491 -ITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544 +T + I +T G P P W + G++ K++ ++ Sbjct: 20023 GVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPTSSTLSIKYASRKN 20082 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y A N G + V + P + V E + +PP E Sbjct: 20083 TGEYTITASNPFGIKDEKVKVKVLDVP----GPPGPIEASSVSAE---KCTLTWLPPEED 20135 Query: 1605 IWYKNGNKLENDKEYN--ITTKEKTSVIRIK----ELKRSHSSKYTIEASNTAGTSSVEV 1658 + + +E + + TK +V+ + +L + + + + A N GT V Sbjct: 20136 GGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYGTGDVTQ 20195 Query: 1659 T--LKVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 + +K+ D P P P I +S+ +VTI WK P DGG ++ Y +E+ E RW Sbjct: 20196 SGPVKMVDSFGPPGPPSKPEI-DNVSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRW 20254 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXX 1772 ++ + + + L+E EY FRV A+N GF E E S+P++ K P Sbjct: 20255 VRASKKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSN 20314 Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKL 1829 + + W +GG + Y VE K+EG W + L Sbjct: 20315 PRITDTTKTTATF-NWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNL 20373 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWT 1887 Y FR+ A N G P + + + P + + ++ +++ Sbjct: 20374 QSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGASIRIF 20433 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 P +P + E +KG++ + S I D + ++ EN G Sbjct: 20434 VPIKGRPAPEVVWYKENVPLKGRAH---IDTTESYTLVVIPECTRYDAGKYVLTLENVAG 20490 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 T +VR+ P PP L+ R + + + W P DGG+ + Y I R+ Sbjct: 20491 KK--TGFVNVRV---VDTPGPP-VNLKPREITKHSITLQWEIPLIDGGSKIKNYIIEKRE 20544 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 T+ + V + + I DL E Y R+ A NE+G+ EP E+ +P + Sbjct: 20545 ATRKAY-SVITTNWQKCSYKIPDLEEAAEYYFRVSAENEMGIGEPAETPDPIR 20596 Score = 146 bits (354), Expect = 6e-33 Identities = 117/431 (27%), Positives = 191/431 (44%), Gaps = 18/431 (4%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPEGPVIMREISRESVTIEW 1687 ++ L+ +Y + A N AG + D + P P +M I+R SV++ W Sbjct: 25282 KVTGLEEGLQYQYRVYAENIAGIGPCTKACDPVSARDPCAPPSQPRVMN-ITRTSVSLSW 25340 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 P DGG ++T Y +E+ E + RW+K + + + L E+ Y FR+IA+N Sbjct: 25341 TKPEFDGGAKVTGYIVERSELPDGRWLKCNFTNLQETYFDVTGLIEDQRYDFRIIAKNAA 25400 Query: 1748 G-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKV 1804 G FSE ES P+ +K +D P + ++ I +E +G P+I + Sbjct: 25401 GLFSEPSESTGPVTVKDDVDPPRITIEDKLRQLVVIKAGEILRIDAEISGRPIPVISWAK 25460 Query: 1805 EIKQ-EGK-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGK 1861 + K+ E K +++ ++ + Q+ + +N GT SL G Sbjct: 25461 DGKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVLTLQNVAGTRSLAVNCKVLDRPG- 25519 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 P S P + ++ T+ TL W P+ NGG+ I +YI+E + +WT +V Sbjct: 25520 ---PSSGPLD--ITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWT-LVYADMK 25573 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 + + + +E IFR+ N G ES + TVP+ PT +E+ V S Sbjct: 25574 ATTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDPFTVPAAPT-DVEVTSVTSE 25632 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 + W P DGG+ + GY I R+ + W+ V K V L+ +L E Y R+ Sbjct: 25633 AMTICWERPISDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRV 25692 Query: 2042 YARNEIGLSEP 2052 +A N GLS P Sbjct: 25693 FAENAAGLSAP 25703 Score = 144 bits (350), Expect = 2e-32 Identities = 217/970 (22%), Positives = 374/970 (38%), Gaps = 63/970 (6%) Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTA---IL 1189 A V W KDG ++ + + + + L + + DD G+Y+ ++ NS + TA ++ Sbjct: 21813 AAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITNSAGEATADINVI 21872 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 +++P E + + T ++ E + + Y + T + ++S Sbjct: 21873 VLDKPGPPTGPIKIEEVTADSVTLSWQPPEY-EGGCSINNYIVEKRDTSTTNWQIVSATV 21931 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSD 1304 RT + CEY + KS+ + VV ++P +I ++ + Sbjct: 21932 ARTTT-KAARLKTGCEYQFRIAAENRYGKSSVIVSEHVVAQYPFEIPHPPGIPAVQSATK 21990 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAGI-YKLR 1361 +++V + I+ I K K++ + + T K+ + GI Y+ R Sbjct: 21991 ESMVVVWNKPSSDGGSKILGYHIESKEKNSLLWVKQNKTIIPDTRFKIGGLEEGIEYEFR 22050 Query: 1362 L--ENNCG--HADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 + EN G A + + P PPGKP + + SS+ + W P+ G I YV Sbjct: 22051 VYAENIVGLSKASKVSEIQVARDPCDPPGKPEAVIVKRSSVTLRWTPPQFDGGIKITGYV 22110 Query: 1417 VEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA-SETTEYYKV 1473 VE +E+ W+ S NI +T+ + L Y FR A N +S S++T + Sbjct: 22111 VEKKELPNGRWMKASFANIIETEFVVSGLVEEQQYEFRVIARNAAGVSSVPSDSTG--AI 22168 Query: 1474 IKETKIQSPTVEKPLK---NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY 1529 + ++ P ++ K N+ E + G P P V W + G++L TA+ Sbjct: 22169 TAKDEVDPPQIDLDAKYSQNVVVNAGESFRIDAGILGKPIPSVHWIKSGEELTNTARLEI 22228 Query: 1530 ENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK--QKH 1584 +N Y + N GE V + +P I Sbjct: 22229 KNTDFTTTLSVKEAIRVDGGQYTLLLKNVGGEKSVIINVKVLDRPGPPDGPISIYGVTSE 22288 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKY 1643 K W T + +G EV Y + + + + K +T ++I +L + + Sbjct: 22289 KCCISWK-TPLHDG--GAEVSHYIVERRETSRLVWTVVELKVQTLNLKITKLLPGNEYIF 22345 Query: 1644 TIEASNTAGTSS-VEVTLKVYDKPS-KPEGP--VIMREISRESVTIEWKPPLDDGGLELT 1699 + N G +E + P PE P V + I+++S+ I W+ P +DGG +T Sbjct: 22346 RVIPVNKYGIGEPLESDPVIAANPFVTPEAPSNVEVSNITKDSMVITWERPTNDGGSAIT 22405 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y +EK + + RW + + + L E Y FRV A+N G + S P V Sbjct: 22406 GYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLLEMRSYEFRVSAENAAGVGKP--SPPTV 22463 Query: 1760 IKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXX 1816 A D + SV + W +GG I Y VE + +W Sbjct: 22464 YFKAADPVFKPGPPNNPKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMC 22523 Query: 1817 X---XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 +KL Y+FRI A N+IG + I L P + Sbjct: 22524 TPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEAPDIDLDAD 22583 Query: 1874 VSES-TSRSV-TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 + + T R+ +L+ P +P + KT + + + S IEN+ Sbjct: 22584 LRKMITVRAGGSLRLFVPIRGRPTPEVKW---GKTEGEINEAAQIDITSSFTSLVIENVN 22640 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 D + ++ EN G T+S + + T P A ++ + N V +W P Sbjct: 22641 RFDSGKYTLTLENASG----TKSAFISVRVLDTPDMP--ANFRVKEITKNSVTLTWEPPL 22694 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DGGA + Y + R+ T+ ++ V N + + I L E Y R+ A NE G+ Sbjct: 22695 LDGGAKIKSYIVEKRESTRKVYSAV--TTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGL 22752 Query: 2052 PLESDEPFKV 2061 P E+ EP K+ Sbjct: 22753 PAETPEPLKI 22762 Score = 144 bits (349), Expect = 2e-32 Identities = 137/560 (24%), Positives = 234/560 (41%), Gaps = 29/560 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-------GD 785 E P+++E ++S V + V +V+G P P W KN L KSD D Sbjct: 1849 EAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNG----ILLEKSDRVYWYWPED 1904 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 +++ +D +KA N G A + A + V+ + F ++ K Sbjct: 1905 HVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQA-----KQVVSFTQTLEDAYAK 1959 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 EK T+ T P + W +NN I + + D + L + ++ + D +Y Sbjct: 1960 EKDTMVTFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQ-DDAEYS 2018 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNK 964 C + AR+ ++ + VK+L+ S E E + EC+ S WY Sbjct: 2019 CAVVDD-DHIRTTARLYVEGAPLEIVKNLE-SVEVPETYSGEFECELSREDAEGTWYFEN 2076 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 KEI+ + D G V D +TS L +K ++ L Sbjct: 2077 KEITPSLKYVVSSRRGRHTLSVKDVRKEDQGKYTFKVGDLKTSATLKMKLRPVTLMQGLS 2136 Query: 1025 DFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 D + E D+A LEV + E + W ++G I + + + KL + N + D Sbjct: 2137 DLTICEGDIAQLEVRFSQENVEGTWMKNGLPISASDRVHIVIDK-LVHKLLVENVNKDDA 2195 Query: 1085 GEYSCI--LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFK 1141 G YS + ++D S + ++TV + EII+ L++ +G KA E +++ D A V+W++ Sbjct: 2196 GIYSFVVPIQDISTSGKLTVQSI--EIISHLKDVHSIEGTKAVLEAKISASDVAAVKWYQ 2253 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201 + + S IQ+ G KQ+L + D G+Y VG + T LTVE+ SI ++ Sbjct: 2254 NDKLLVASERIQMVAKGTKQRLVLNRSFGSDEGQYKMAVGRVETTCNLTVEKVSI---IK 2310 Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 E + + VE+ +D W K ++ K+ + S K +L I +D Sbjct: 2311 HMEDCVCTETQNVTFEVELSHTGIDAYWTFKNQPLKAGPKYKIESKGKHYSLTIINAMKD 2370 Query: 1262 DQCEYTCVLLDAKSTTKLKV 1281 ++ Y + S+ KL V Sbjct: 2371 EEGLYAFAAGEKISSAKLTV 2390 Score = 141 bits (341), Expect = 2e-31 Identities = 112/431 (25%), Positives = 183/431 (42%), Gaps = 23/431 (5%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYD---KPSKPEGPVIMREISRESVT 1684 R+ L S ++ + A N AG S V K D KP P P + +SR SV Sbjct: 22433 RVTGLLEMRSYEFRVSAENAAGVGKPSPPTVYFKAADPVFKPGPPNNPKVAY-VSRASVV 22491 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIA 1743 + W P+ DGG E+ Y +E E ++ W+ ET + +KL E EY FR+ A Sbjct: 22492 LHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITETRFEAKKLLEKHEYKFRICA 22551 Query: 1744 QNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIID 1801 N +G E + ++I+ L+ P I + F + +P + Sbjct: 22552 VNKIGVGETADIPGSVIIEDKLEAPDIDLDADLRKMITVRAGGSLRLFVPIRGRPTPEVK 22611 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 + + + + I+ ++ + ++ + N GT + S + Sbjct: 22612 WGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLTLENASGTKSAFIS------VR 22665 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 L P P NF V E T SVTL W P +GG+ I +YI+E + K ++ + T Sbjct: 22666 VLDTPDMPANFRVKEITKNSVTLTWEPPLLDGGAKIKSYIVEKRESTRKVYSAVTTCNKM 22725 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 + IE ++E FR+ AEN G+ LP E+ K + VP PP + + V Sbjct: 22726 TWK--IEPLEEGSIYFFRVLAENEHGIGLPAETPEPL--KISEVPQPP-GKVSVVDVTRK 22780 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 V W PE DGG+ + Y + ++ + W + V L + +L++ Y+ R+ Sbjct: 22781 SVSLKWEKPEHDGGSRITYYEVEMQAKDQDKWSLCAQ--VKALDTVVTNLAQGGEYIFRV 22838 Query: 2042 YARNEIGLSEP 2052 A N+ G S+P Sbjct: 22839 IAVNDKGKSDP 22849 Score = 140 bits (340), Expect = 3e-31 Identities = 91/320 (28%), Positives = 143/320 (44%), Gaps = 9/320 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KW-KXXXXXX 1820 LD P I +SV + W P +GGSPI +Y V +K+E W + Sbjct: 26202 LDRPGPAVGPVEMCDITEDSVSLKWLPPAYDGGSPITNYIV-LKRETTTANWIEVSSAVA 26260 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 +I KL+ YQFRI A N G S + +T+ T P P VS T Sbjct: 26261 RCTIKIMKLNTGVEYQFRIKAENRFGIS-EHIDSQTVTVSLPYTLPVAPSQPWVSAVTKE 26319 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 S+ + W EP S+GGS + Y ++ K W K+ T + N+ F++ Sbjct: 26320 SIVVNWKEPSSDGGSHVFGYHLQMKDRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKV 26379 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +AEN G+ ++S L A PP + + + + N + +W P +DGG+ + G Sbjct: 26380 AAENAAGIGPISKSSDPVLAIDAC--EPPNS-VRVTDITKNSISLAWQKPSYDGGSKITG 26436 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEPF 2059 Y I ++D K W + +V KF + L++N +Y R+ A+N +G +S P E P Sbjct: 26437 YLIEMKDGPKGRWSKANLTNVTDTKFTVSGLTQNESYEFRVMAKNAVGSVSNPSEIVGPV 26496 Query: 2060 KVIPGEGSHADEEPGEQTEV 2079 + G+ + P E +V Sbjct: 26497 TCVDTYGAPEVDLPQEYLDV 26516 Score = 140 bits (339), Expect = 4e-31 Identities = 111/442 (25%), Positives = 194/442 (43%), Gaps = 26/442 (5%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDK---PSKPEGPVIMREISRESV 1683 ++ L+ +Y + A N AG S+ V K D PS P P I+ + ++ SV Sbjct: 25677 VKASNLREGCEYEYRVFAENAAGLSAPSVPCPLTKAEDPLFLPSPPAKPKII-DSTKTSV 25735 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 T+ W PL DGG +T Y +E +++ W + + E + + L EY+F V + Sbjct: 25736 TLSWNKPLFDGGSPVTGYMVEYRNTNDDDWTVGVNNTKSTE-FTVVGLTSGTEYVFVVRS 25794 Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXX--IDNESVYITWFPSEKNGGSPII 1800 N +G SE + E++P V K D P + + S + P + ++ Sbjct: 25795 INKIGPSEPSPETDPQVAKEREDEPVFLISNEMRKTLVVKDGSSFTLRVPFKGKPVPHVM 25854 Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 K ++ + I++ + + + ++ + +N GT+ +T+ Sbjct: 25855 WNKPDVDLRVRA-SIDTTDTCTSVTIEQATRDDSGKYTVTLQNVAGTAT-------LTLS 25906 Query: 1861 -KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919 K L P P + V E T S T+ W P++ GG+P+ NY+++ + W++I Sbjct: 25907 VKVLDSPGPPAHIEVKEVTKSSATITWDTPDNEGGAPVKNYLVDLREATKMGWSRISNSC 25966 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 + + + N++E FR++ EN GV +P E++ K PSPP L + V Sbjct: 25967 PRL-TYKVTNLQEGGVYYFRVTGENEYGVGVPLETKEG--TKITEKPSPP-PKLGVTDVT 26022 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 V +W PE DGG+ + Y + + + W++ G + F + L EN Y Sbjct: 26023 KESVSLAWLKPEHDGGSRITNYLVEALEKGQQKWIKCG--STKSTHFVVDGLRENAEYYF 26080 Query: 2040 RIYARNEIGLSEPLESDEPFKV 2061 R+ A N GLS+P + P V Sbjct: 26081 RVRAENHAGLSDPKDMVLPVLV 26102 Score = 140 bits (338), Expect = 5e-31 Identities = 156/605 (25%), Positives = 243/605 (40%), Gaps = 45/605 (7%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437 P PP P +++ SSI++ W +P G I+ Y+VE++ D EW+ KN+ T+ Sbjct: 19260 PGPPAFPKVVDSTHSSISLSWTKPAYDGGCEILGYLVEFKRADAEEWMKCNVPKNLQATK 19319 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 ++ L N+ Y+FR AVN++ + SE E K + + + +P E K + Sbjct: 19320 FNVTGLIDNTEYQFRVSAVNKIGFGEPSEVPE--KHLAKDILLAPEAELDADLRKALVLR 19377 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKC 1550 + + G P PK TW + LK + T E Y Sbjct: 19378 AGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYDAGKYVL 19437 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYK 1608 N G + VV + P + N +K+ K V W + G P + K Sbjct: 19438 TLENSSGTKSYTIVVKVLDTPGPPV-NLIVKETSKDHVSITWDAPLIDGGSPVKSYVVEK 19496 Query: 1609 NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +L K + E KTS RI L+ + + + A N G T K Sbjct: 19497 ---RLAERKAWTCVAPECPKTS-FRITNLEAGQAYCFRVLAENIYGIGEGCETAGPV-KA 19551 Query: 1667 SKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 S+ GPV EI++ S T+ WK P+ DGG + YA+E E ++ +W + + V Sbjct: 19552 SEQPGPVAEFKSMEITKNSCTLGWKKPISDGGSHVVAYALEICEGED-KWKLL--MKSKV 19608 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX-XXXXIDNE 1782 Y I L E EY FRV A N E I+ K + P+ + E Sbjct: 19609 TQYTIGDLVEGKEYSFRVKAINESAEGPPTELT-ILAKDQIVPPNCDLKGLPDSSYVAKE 19667 Query: 1783 SVYITWFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839 + +P + +K V + G+ I+ +F I Sbjct: 19668 GTTVRLNIPITGIPAPAVIWKKGDVTLSDSGRI-SVESTTTNTVLLIRDCHRGDAGKFTI 19726 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 RN GT D K+ +GK S P F E T+ ++T++W P+ +GGS +TN Sbjct: 19727 ILRNSAGTK-EAAIDIKV-VGKPGIC-SGPIKF--DEITAEAITVEWGPPKDDGGSEVTN 19781 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 Y +E + W VTV ++ ++ + + + E IFR+ AEN G+ S V Sbjct: 19782 YFLEKRHSTANKW---VTVASAIQKNSMRVTRLHDGTEYIFRVCAENKYGIGEFLRSDPV 19838 Query: 1958 RLEKH 1962 L KH Sbjct: 19839 -LAKH 19842 Score = 138 bits (335), Expect = 1e-30 Identities = 167/713 (23%), Positives = 278/713 (38%), Gaps = 54/713 (7%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKT 1436 D PPG P + + S+ + W PE G S + YVVE +++ W+ S NI +T Sbjct: 23154 DPCDPPGTPVPVIVTRHSVKLRWTPPEYDGGSLVTGYVVEKRDLPEGRWMKASFANILET 23213 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKN---IT 1492 + ++ L + Y FR A N +S SE+T V + +++ PT E + +T Sbjct: 23214 EFTVTGLIEDCKYDFRVIARNGAGSVSRPSESTG--SVTAKDEVEPPTYEVASEYSQILT 23271 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYEN---RXXXXXXXXXXXXXXXY 1548 + L G P P + W++ +++ +A+A +N + Y Sbjct: 23272 VNAGDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEIKNTDFKAVLVVKDAIRIDGGQY 23331 Query: 1549 KCIAFNDHGEVETSCVVGIQQKP-----VITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 N G S V + +P +T+S K WL G Sbjct: 23332 TLHLSNVAGSKSVSFNVRVLDRPGPPEGPLTVSGVT---NEKCSLSWLPPRHDGG---SS 23385 Query: 1604 VIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLK 1661 + +Y + + + + + + ++ ++ +L + + + + A N G +E Sbjct: 23386 ISYYVIQKRETSRLAWTVVSGDCGATMFKVTKLLKGNEYIFRVMAVNKYGVGEPLESRAV 23445 Query: 1662 VYDKPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 + P GP + + ISR+S+T+ W P DGG E+ Y +EK + RW K Sbjct: 23446 IMRNPFVAPGPPQDLEITNISRDSMTVCWTRPESDGGNEIVGYIVEKRDRAGIRWTKCNK 23505 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778 + + L E+ EY FR+ A+N G + S+P V A D Sbjct: 23506 RRVTDLRFRVTGLTEDHEYEFRLSAENAAGVGQP--SQPTVYYKACDPTFKPGQPTNAHL 23563 Query: 1779 IDN--ESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXX---XXXXXXARIQKLSIN 1832 +D SV + W +GG I Y VEI K + ++W I KL+ + Sbjct: 23564 VDTTKNSVTVAWSRPIYDGGLDIQGYVVEISKADEEEWITCTPPTGLNDTKFSITKLTEH 23623 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 Y+ RI A N++G P + K + P + SE V Sbjct: 23624 QEYKVRICALNKLGVGEPVPIQGSV---KPVDKMDAPEIELDSELRKGIVV-------HA 23673 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 GGS N + + + +WTK G + I+ + + I N G T Sbjct: 23674 GGSMRINIPFKGRPIPEINWTK--DDGDLPDKAQIDKGPDFTHLTINICDRNDAGKYTLT 23731 Query: 1953 ESQSVRLEK---HATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 S + V P AP L ++ + N V W P DGG+ + Y I R+ Sbjct: 23732 LQNSAGTKSAFVSVKVLDTPGAPQNLFVKDITRNYVTLVWEPPLIDGGSKIKNYIIDKRE 23791 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 T+ + + + F + DL+E Y R+ A NE G+ P+E++E K Sbjct: 23792 STRQGFTNI-TTKCSKTSFRVGDLTEGGIYYFRVMAENEFGIGLPVETEESVK 23843 Score = 137 bits (332), Expect = 3e-30 Identities = 167/772 (21%), Positives = 301/772 (38%), Gaps = 57/772 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KK + EG + ECR+ +++WL GE + D +++ + + Sbjct: 7218 PPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSFDDNS---- 7273 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +VL I + G YT VA N G AS L ++ + PP + L + V G++V Sbjct: 7274 AVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQE-PRYPPVFDKKLVPVDVSVGDTV 7332 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L + G+ +TW K++K ++ +T +TILK K D G Y+ A N Sbjct: 7333 ELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHLTILKADKA-DSGRYSCHASN 7391 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK--EKGTIKLVARVTRNPVPSITWY 867 G S ++V+E PP F + T++ E +K+ RV + ++ WY Sbjct: 7392 DVGKDSCSTEVSVKE----RKIPPSFTKK-PSTTIEDIEGKVVKIEGRVAGSQPLTVNWY 7446 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ I S+ F L I DSG Y C A+N AG +S V I +K Sbjct: 7447 KDGREIFTSDFYDVTFKSSLAVLCIKKSQLS-DSGTYVCKATNEAGTASFEVSVHITAQK 7505 Query: 928 VTFVKHLQ-KSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 V L K EG+T+ L C S + +W +++E+S + +I Sbjct: 7506 VPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITFVDGTATL 7565 Query: 985 XXXXXXXXDVGVIKCIVKDQETS-----TMLVVKETIPEFIRKLQDF---------EVKE 1030 D G C ++ + + P+ ++K + + E Sbjct: 7566 EMTRVSKTDSGDYLCKATNEAGNKPGAPAPAQAAPSPPQEVKKFDNLFFIEVPKSVHIVE 7625 Query: 1031 KDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 K A ++ + +V W + + E++G K+ I+ + D G+Y C Sbjct: 7626 KGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRISIEQKGQEAKMEIKEVTKSDSGQYRC 7685 Query: 1090 ILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145 + ++ C+ ++ V E + ++ +K K+ E + L+R Sbjct: 7686 VASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPSKQKSPKEEKDIDIVELLRNVDPKEY 7745 Query: 1146 IQFSNHIQLT-IDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203 +++ +T G Q ++ + + ++G E+ + L + + Sbjct: 7746 EKYARMYGITDFRGLLQAIEFLKKEKELESGRPEGEIVGRESEEDLAKLVADLQKRMEQT 7805 Query: 1204 EFILVPAN-TDAYLTVE----------IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 E + V + TD TV+ I + ++WYK ++ +K+ + + Sbjct: 7806 EPVTVARDITDQTTTVKKEAVFECEIKINYPEITLSWYKGTQKLDSGDKYDIKIVGDRHI 7865 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 L I+ C D+ Y V S+ KL V E + D K G TL Sbjct: 7866 LKIKDCQTRDEGNYRIVCGPHISSAKLTVLEAEVEKPMQDVAG----KEGQTCTLTCQLS 7921 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 P +W N K+++ ++ + + L+IK V D G Y + +N Sbjct: 7922 V-PNVKTQWFRNGKLLEPHSRYTCAVANYTQKLSIKDVRPEDQGEYTCKYKN 7972 Score = 136 bits (328), Expect = 8e-30 Identities = 163/676 (24%), Positives = 279/676 (41%), Gaps = 48/676 (7%) Query: 1216 LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL--- 1271 LT +I L ++ WY+ + + K+ + SD + +L + ++D+ YTC + Sbjct: 30185 LTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLSVMTDEQEDEGLYTCRAVNEA 30244 Query: 1272 -DAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + +++ KL ++ +F P + +Y G+ + L V Y P P W K + Sbjct: 30245 GEIETSGKLLLQAAPQFHPGF-PLKEKYYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLN 30303 Query: 1330 KCKHTKPSIDSKSASLTIKKVEN-TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 ++ L I+ V+ T+AG YK++L N G D + V I DKP P P Sbjct: 30304 PSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLSNKFGTVDTVLRVEIQDKPLLPEGPV 30363 Query: 1389 ILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKN-ITKTQTSIQNLKT 1445 +++ + SS+ I W P++ G S I Y+VE +E + +W V + ++ T + NL Sbjct: 30364 VVDALLKSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRVPNLIE 30423 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIEL--- 1501 +S Y FR A N+ IS++ E VI ++ + P V ++P + T+ + + Sbjct: 30424 SSGYYFRVSAQNQYGISESLEIPSV--VIIKSPFEKPGVPQRPFVSSVTKDSCVVSWKPP 30481 Query: 1502 TCIFGGVPQPKVTWYRDGKKLK----TAKATYENRXXXXXXXXXXXXXXXYKCIAF---N 1554 T G + R+ K+ K T +E KC + Sbjct: 30482 TSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETSYTAKGLLEGFEYEFRVKCENIGGES 30541 Query: 1555 DHGEVETSCVVGIQ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 D E+ + + P D+ K+K + VT V+ G P P V WYKNG Sbjct: 30542 DWSEISEPVIPKSDTALRAPFFKDELRDMCVKYK-ANATFVTKVV-GHPKPVVKWYKNGK 30599 Query: 1612 KLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSS------VEVTLKVY 1663 ++ D + K + I + ++ Y I A+N G+ S VEV K+Y Sbjct: 30600 EILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIY 30659 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 P +G + I E VTI K P+ + + + +N + +V Sbjct: 30660 -LPLHLQGMGAVHAIRGEVVTI--KIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFT 30716 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 ++ + + + A+N G ++ + + + A DVP I ++ Sbjct: 30717 SLVFLKGVQRKDSGYYIICAKNRFG----MDKQTVELDVA-DVPD-PPKDVKVSDIGRDT 30770 Query: 1784 VYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 + +TW P +GGS II+Y +E G +W + L T YQFR+ A Sbjct: 30771 LTLTWSPG-NDGGSEIINYIIEKCPTTGDRWIRVAQTSESQYTVMSLFGKTKYQFRVIAE 30829 Query: 1843 NEIGTSLPYTSDDKIT 1858 N G S P D +T Sbjct: 30830 NRFGVSDPSAPTDPVT 30845 Score = 135 bits (327), Expect = 1e-29 Identities = 178/772 (23%), Positives = 308/772 (39%), Gaps = 64/772 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMY 691 PP F KK V G + LEC + + W ++I N ++ +E+ H+ Sbjct: 7314 PPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKISCVENTPHL- 7372 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ++LK K G Y+ A N G+ S + +K + P +P ++ +G+ Sbjct: 7373 -TILK---ADKADSGRYSCHASNDVGKDSCSTEVSVKERKIPPSFTKKPSTTIEDIEGKV 7428 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL--KPKKVKDEGVYTLKAEN 809 V + +V G+ T+ W K+ + + S+ +L K ++ D G Y KA N Sbjct: 7429 VKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKSSLAVLCIKKSQLSDSGTYVCKATN 7488 Query: 810 SEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 G A E S IT ++ PP F + +TV E T+ L V +P I W Sbjct: 7489 EAGTASFEVSVHITAQKV------PPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWM 7542 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVE 926 ++ +S S F L +T V S+ DSGDY C A+N AG K A Sbjct: 7543 KDRRELSSSANTKITFVDGTATLEMTRV-SKTDSGDYLCKATNEAGNKPGAPAPAQAAPS 7601 Query: 927 KVTFVKHLQKSYETEEGKTV-ILECQTSHTVS---------TKWYHNK-KEISGMDHREI 975 VK + E K+V I+E T+ ++ KW K ++++ I Sbjct: 7602 PPQEVKKFDNLFFIEVPKSVHIVEKGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRISI 7661 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV---KETIPEFIR-----KL 1023 Q+G+ D G +C+ ++ E ST L V KET E ++ Sbjct: 7662 EQKGQEAKMEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPSK 7721 Query: 1024 QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 Q +EKD+ I+E+ N + + +E+ + + + ++K S Sbjct: 7722 QKSPKEEKDIDIVELLRNVDPKE--YEKYARMYGITDFRGLLQAIEFLKKEK-ELESGRP 7778 Query: 1084 EGEYSCILRDESCTAEVT-----VVELPPEIITR-LQNQKVNKGNKATFE--IELTKGDA 1135 EGE +E V + + P + R + +Q +A FE I++ + Sbjct: 7779 EGEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTVKKEAVFECEIKINYPEI 7838 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195 + W+K ++ + + I G + LKI DC D G Y G +A LTV E Sbjct: 7839 TLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTRDEGNYRIVCGPHISSAKLTVLEAE 7898 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 + + + + LT ++ + W++ ++E ++T + L I Sbjct: 7899 VEKPM---QDVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEPHSRYTCAVANYTQKLSI 7955 Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 + +DQ EYTC + ++T L +E + F +I + + + D Sbjct: 7956 KDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRIQNIVVREHQSATFECEVSFDNAV 8015 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK--LRLE 1363 D W ++ + K+T S + + + I+ V + D G+Y +RLE Sbjct: 8016 VTWYKDTW----ELKESPKYTFRS-EGRRHFMIIRNVSSADEGVYSVIVRLE 8062 Score = 133 bits (321), Expect = 6e-29 Identities = 96/334 (28%), Positives = 142/334 (42%), Gaps = 12/334 (3%) Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 I++ N + + A N +G E I+I LD P + V I+ Sbjct: 24006 IKEANREDSGKYTITATNNIG--TVTEEVAIII---LDKPGPPTGPVKIDEVSATYVVIS 24060 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEI 1845 W P GG I +Y VE + W+ +I KL + YQFR++A N Sbjct: 24061 WEPPVYTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRY 24120 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 G S S + + T P+ P VS T +T++W P +NGGSPI Y +E K Sbjct: 24121 GKSGSIDSTP-VVVSYPFTEPAAPGAPFVSSVTKDHMTIEWKPPSNNGGSPIIGYHLERK 24179 Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965 WTK+ + + ++E E +R+ AEN G+S S V A Sbjct: 24180 EKNSILWTKLNKLLITDTRLRTNGLEEGIEYEYRVFAENIAGIS---PSSKVSESVVARD 24236 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P P E ++ N++ W P++DGG+ + GY I + + WM+ ++ + Sbjct: 24237 PCDPPGTPEAIVITRNLITLQWTKPQYDGGSVITGYIIERKKLPDGRWMKASFTNIIDTQ 24296 Query: 2026 FNIRDLSENHTYMIRIYARNEIG-LSEPLESDEP 2058 F I L E Y R+ ARN G LS P ES P Sbjct: 24297 FTITGLHEEQRYEFRVIARNAAGILSVPSESTGP 24330 Score = 132 bits (318), Expect = 1e-28 Identities = 108/433 (24%), Positives = 183/433 (42%), Gaps = 26/433 (6%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK------PSKPEGPVIMREISRESVT 1684 R L H ++ + A N AG + + Y P P P + + S +V+ Sbjct: 24597 RATGLTEGHFYEFRVSAENAAGVGTPSEPSEYYKACDATYPPGPPNNPKVT-DHSSTTVS 24655 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 + W P+ DGG ++ Y +E + + + W + + ++KL EN EY FR+ A Sbjct: 24656 LAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICA 24715 Query: 1744 QNPVGFSEALESEPIVIKTA-LDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIID 1801 N G E ++ VI L+ P + S + F + + P + Sbjct: 24716 VNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFVTIRGRPEPEVK 24775 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 +K ++ + I ++ T ++ + N IG+ + + K Sbjct: 24776 WKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLTLENNIGSKSAFVNV------K 24829 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VG 1919 L PS P NF V + SV L+W P+ +GG+ IT+YI+E + K ++T I V Sbjct: 24830 VLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAKITHYIVEKRESKRLAFTSITNNCVR 24889 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 S+ +++++E FR+ A N +GV LP E + K + P PP + + V Sbjct: 24890 NSIR---VDDLQEGGLYHFRVLAVNELGVGLPAE--TTEAVKISQAPLPP-GKITVIDVT 24943 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 + V SW P+ DGG+ + GY + + W V + L+ I L+ Y Sbjct: 24944 RHTVTLSWEKPDHDGGSKITGYMVEMMTKGSDKW--TACVTIKALEATIEGLTTGEEYSF 25001 Query: 2040 RIYARNEIGLSEP 2052 RI A N+ G S+P Sbjct: 25002 RITAINDKGKSDP 25014 Score = 131 bits (317), Expect = 2e-28 Identities = 89/330 (26%), Positives = 142/330 (43%), Gaps = 11/330 (3%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 + + A NP G ++ E + +K LDVP + E +TW P E++GG Sbjct: 20086 YTITASNPFG----IKDEKVKVKV-LDVPGPPGPIEASS-VSAEKCTLTWLPPEEDGGCS 20139 Query: 1799 IIDYKVEIKQEGKKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 I Y +E ++ + R KL Y FR+ A N+ GT T Sbjct: 20140 IKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYGTG-DVTQSGP 20198 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 + + + PP P + + +VT+ W P +GGS I YI+E K +G W + Sbjct: 20199 VKMVDSFGPPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGYIVERKERRGMRWVRAS 20258 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEI 1975 S + + E+ E FR++AEN G P+E SQ V + A P PP+ P I Sbjct: 20259 KKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQPVMTKDIAYPPGPPSNP-RI 20317 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 +WG P +DGG + GY + + W++ + + +F + +L Sbjct: 20318 TDTTKTTATFNWGRPFYDGGLDVTGYIVEHKKEGDDDWVQDTTIPLRITEFVVSNLQSGG 20377 Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKVIPGE 2065 Y R+ A N GL EP E ++ +++ E Sbjct: 20378 KYHFRVSALNSEGLGEPSEVEQVVELVDRE 20407 Score = 131 bits (317), Expect = 2e-28 Identities = 84/298 (28%), Positives = 136/298 (45%), Gaps = 6/298 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-X 1821 LD P + E +TW P ++NGG+ I Y VE ++ + W Sbjct: 25515 LDRPGPSSGPLDITGLTAEKCTLTWGPPQENGGAEIQHYIVEKRETSRLAWTLVYADMKA 25574 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 ++ KL Y FR+ N+ GT SD + T P+ P + V+ TS + Sbjct: 25575 TTCKVTKLLKGNEYIFRVRGVNKYGTGEALESDPAKAMDP-FTVPAAPTDVEVTSVTSEA 25633 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 +T+ W P S+GGS I+ Y+IE + G W ++ N++E E +R+ Sbjct: 25634 MTICWERPISDGGSSISGYVIEKREKSGLRWVRVNKKPVYDLRVKASNLREGCEYEYRVF 25693 Query: 1942 AENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 AEN G+S P+ + E +PSPP P I +++ + SW P +DGG+P+ G Sbjct: 25694 AENAAGLSAPSVPCPLTKAEDPLFLPSPPAKPKIIDSTKTSVTL-SWNKPLFDGGSPVTG 25752 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 Y + R+ W VG + + +F + L+ Y+ + + N+IG SEP +P Sbjct: 25753 YMVEYRNTNDDDW-TVGVNNTKSTEFTVVGLTSGTEYVFVVRSINKIGPSEPSPETDP 25809 Score = 130 bits (315), Expect = 3e-28 Identities = 117/565 (20%), Positives = 231/565 (40%), Gaps = 36/565 (6%) Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375 P +IV + +++ K T+ + ++++ EN G ++ E+ Sbjct: 13829 PITNYIVEKRDVRRKGWQAVDTTVKELKYTVTPLNEGSLYVFRVAAENAVGPSEFCELED 13888 Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++L K P PP I E+ + +++ W+ P+N G ++ YV+E +E T W+ Sbjct: 13889 SVLAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRPVLRYVIEKKEKLGTRWVKS 13948 Query: 1431 KNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 + + ++ + +F+ A NE + SE T+ V+ E P+ + L Sbjct: 13949 GKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTDI--VVIEDPTGPPSPPQEL 14006 Query: 1489 KNITTEPNEDIELTCIF----GGVP----------QPKVTWYR-DGKKLKTAKATYENRX 1533 +IT + I + GG P W R + + +K K + Sbjct: 14007 -HITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNSRPVKELKYRAGDEE 14065 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 + ++ ++ E + P + +D+ G++ + Sbjct: 14066 GIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCSPTLDFQTKDLVVVE--GEKMHL 14123 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 +P P++ W+K+GN+++ D + + + + + + +Y + N G Sbjct: 14124 PIPFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLEVPSCLHADAGQYKVTLENRNG 14183 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 +S + +KV P P ++ EI++ S + W+PP DGG + Y +++ E Sbjct: 14184 ATSGTINVKVIGLPG-PCKDIVASEITKSSCKVSWEPPDYDGGSPILHYVLQRREAGRRT 14242 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXX 1771 ++KV + + ++ ++ L +N EY FRV A N +G E +E P++ + P Sbjct: 14243 YVKVMSGENKL-SWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPPV 14301 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQK 1828 +ESV +TW P +GGS I+ Y +E +G+ + ++ Sbjct: 14302 DVETHNP-TSESVTLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKG 14360 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTS 1853 L+ YQFR+ A N G S P S Sbjct: 14361 LTHEKQYQFRVRAENAAGVSDPSRS 14385 Score = 129 bits (311), Expect = 9e-28 Identities = 139/601 (23%), Positives = 238/601 (39%), Gaps = 33/601 (5%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXX----XXXXXYKCIAF 1553 + L ++ G P P++ W+ K L ++ EN YK Sbjct: 30279 LRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQLS 30338 Query: 1554 NDHGEVETSCVVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N G V+T V IQ KP++ D K V W G I K Sbjct: 30339 NKFGTVDTVLRVEIQDKPLLPEGPVVVDALLKSSVIISWKPPKDDGGSMITNYIVEKREA 30398 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVYDK 1665 K E ++ + +++ + R+ L S + + A N G S SV + ++K Sbjct: 30399 K-EGEQWHLVSSAVSGTTCRVPNLIESSGYYFRVSAQNQYGISESLEIPSVVIIKSPFEK 30457 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P P+ P + ++++S + WKPP DGG ++ Y +EK E N+WI V + + Sbjct: 30458 PGVPQRPFVS-SVTKDSCVVSWKPPTSDGGAKIKNYFLEKREKKQNKWIAVTTGEIHETS 30516 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 Y + L E EY FRV +N G S+ E SEP++ K+ + + Sbjct: 30517 YTAKGLLEGFEYEFRVKCENIGGESDWSEISEPVIPKSDTALRAPFFKDELRDMCVKYKA 30576 Query: 1785 YITWFPSEKNGGSPIID-YK--VEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIY 1840 T+ P++ YK EI +G K K I N ++I Sbjct: 30577 NATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQEFKGGYFQLVISNADENDAAAYQIR 30636 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N++G+ + D K P V VT+K P S P+ + Sbjct: 30637 ATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKI--PISGKPDPVVTW 30694 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 + + ++ +++ ++ ++ KD + I A+N G+ + Q+V L+ Sbjct: 30695 QKGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKNRFGM----DKQTVELD 30750 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 A VP PP +++ +G + + +W +P DGG+ ++ Y I T W+ V + Sbjct: 30751 V-ADVPDPPK-DVKVSDIGRDTLTLTW-SPGNDGGSEIINYIIEKCPTTGDRWIRVAQTS 30807 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGS--HADEEPGEQTE 2078 + ++ + L Y R+ A N G+S+P +P + + + DEE E E Sbjct: 30808 ES--QYTVMSLFGKTKYQFRVIAENRFGVSDPSAPTDPVTTKEDKLAIRNYDEEVDETRE 30865 Query: 2079 V 2079 V Sbjct: 30866 V 30866 Score = 127 bits (307), Expect = 3e-27 Identities = 87/302 (28%), Positives = 133/302 (44%), Gaps = 7/302 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822 +D+P +D ++ + W ++GGS I +Y VE + W Sbjct: 18659 MDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSNITNYIVEKCDVTRGDWVTAVSCTKT 18718 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 R+ KL+ Y FR+ A N G S P S+ K+ PPS+P N V++ + V Sbjct: 18719 SCRVGKLTCGKEYGFRVRAENRFGISEPIYSE-KMIARHPFDPPSEPLNCCVNKVSKEFV 18777 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 L W +P ++GGS +T Y IE K W + V E+ + E E FR+SA Sbjct: 18778 VLSWEKPVNDGGSALTGYFIERKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFRVSA 18837 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 N G P++ Q+ + + V PP P EI V + V W P+ DGG+ L+GY Sbjct: 18838 VNKAGQGKPSK-QTDFITARSPV-DPPGKP-EIIDVTKSSVSLVWSRPKHDGGSKLIGYY 18894 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + + + W+ V N K + + L E Y RI A+ I +S P E + Sbjct: 18895 VEFLKLKEDKWVRVNSNSQNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEESDVIP 18954 Query: 2061 VI 2062 +I Sbjct: 18955 II 18956 Score = 125 bits (301), Expect = 2e-26 Identities = 118/447 (26%), Positives = 201/447 (44%), Gaps = 37/447 (8%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISR 1680 KTS R+ +L + + A N G S + K+ +D PS+P + ++S+ Sbjct: 18717 KTSC-RVGKLTCGKEYGFRVRAENRFGISEPIYSEKMIARHPFDPPSEPLNCCV-NKVSK 18774 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 E V + W+ P++DGG LT Y IE+ E ++ W++ +V Y L E EY FR Sbjct: 18775 EFVVLSWEKPVNDGGSALTGYFIERKERNSLLWVRTNEVLVRSTEYTCSGLIEGLEYTFR 18834 Query: 1741 VIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A N G + + +++ I ++ +D P + SV + W + +GGS + Sbjct: 18835 VSAVNKAGQGKPSKQTDFITARSPVDPPGKPEIID----VTKSSVSLVWSRPKHDGGSKL 18890 Query: 1800 IDYKVE-IKQEGKKWKXXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 I Y VE +K + KW + + L Y+FRI A+ I S+P Sbjct: 18891 IGYYVEFLKLKEDKWVRVNSNSQNVPKEEYIVPGLEEGAQYKFRIIAKTAINVSVPSEES 18950 Query: 1855 DKITIGKTLTPPS-----QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 D I I PP + +N +V ++ +V L E E G P+ ++ K Sbjct: 18951 DVIPIIAEHVPPRVEISLEMKNLIVVKA-GANVCL---EAEVY-GKPMPK-VVWKKDGAP 19004 Query: 1910 KSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 + + + VH +E ++ K+ + I+AEN G ++S +++L K P Sbjct: 19005 LKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSG----SKSANIKL-KVLDKPG 19059 Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKF 2026 PP A + I V ++ V W P DGG+ + Y + R+ ++ W +V ++ Sbjct: 19060 PP-ASVRISHVFADRVKLRWEPPLADGGSEITNYIVDKRETSRANWAQVTANINGQITDC 19118 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPL 2053 ++ L E H Y RI A N+ G+ +P+ Sbjct: 19119 SVEKLIEGHEYEFRISAENKYGVGDPI 19145 Score = 124 bits (298), Expect = 4e-26 Identities = 109/452 (24%), Positives = 202/452 (44%), Gaps = 33/452 (7%) Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSS-----KYTIEASNTAGTSSVEVTLK--VYDKPSK 1668 D+ + K T+VIR K ++ + ++ + A N AG + + + + Sbjct: 26345 DRNSILWQKVNTTVIRATHFKVTNVNAGLIYEFKVAAENAAGIGPISKSSDPVLAIDACE 26404 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YC 1727 P V + +I++ S+++ W+ P DGG ++T Y IE + RW K A++ +T + Sbjct: 26405 PPNSVRVTDITKNSISLAWQKPSYDGGSKITGYLIEMKDGPKGRWSK-ANLTNVTDTKFT 26463 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 + L +N Y FRV+A+N VG S + SE + T +D +D Sbjct: 26464 VSGLTQNESYEFRVMAKNAVG-SVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAG 26522 Query: 1788 WFPSEKNG----GSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLS-INT-TYQFRI 1839 K G P I++ + K+ G + +++ + +NT TY+ +I Sbjct: 26523 ATVQLKIGIVAKPQPTIEWYKDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKI 26582 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 +N +G++ ++ + PP+ F + T+ ++T+ W P GG+ +T+ Sbjct: 26583 --KNSLGSAYAAV---RVLVQDKPGPPAGEIQF--KKITADTMTIMWDPPADEGGAMVTH 26635 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK---EKDEIIFRISAENTVGVSLPTESQS 1956 YI+E + W+ I + CI + + +E IFR+ N GV P ES+ Sbjct: 26636 YIVEKRETSRIMWSII----SEKLQDCIVTVPRLIKGNEYIFRVRGVNKHGVGDPLESRP 26691 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 V + PS P+ P ++ M+ + + W P DGG+ + GY + R+ W +V Sbjct: 26692 VIAQNSFVHPSQPSKP-QVTMITRSTMTVVWERPSLDGGSDIDGYYLEKREKKSLQWFKV 26750 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 K + + + +L+E + Y R+ A N+ G Sbjct: 26751 IKDPIRDTRQKVHNLTEGNEYQYRVCAINKAG 26782 Score = 123 bits (297), Expect = 5e-26 Identities = 92/319 (28%), Positives = 132/319 (41%), Gaps = 9/319 (2%) Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815 PI +K LD P + E Y+ W +GG+ I Y +E ++ + W Sbjct: 24428 PINVKV-LDRPGPPDGPLKVTGVAAEKCYLHWSHPSHDGGASISHYIIEKRETSRLSWTV 24486 Query: 1816 XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV 1874 + ++ KL Y FR+ A N+ G P S+ + P P Sbjct: 24487 VEPKIQAISYKVTKLLPGNEYIFRVMAVNKYGIGEPLESEP-VLAKNPFNKPGPPSTPEA 24545 Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 S T S+ L W PE +GGS I +++E + +G WTK + + E Sbjct: 24546 SAITRDSIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLNDLRFRATGLTEGH 24605 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVP-SPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 FR+SAEN GV P+E AT P PP P ++ S V +W P +D Sbjct: 24606 FYEFRVSAENAAGVGTPSEPSEYYKACDATYPPGPPNNP-KVTDHSSTTVSLAWSRPIYD 24664 Query: 1994 GGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 GGAP+ GY + +D+ + W + V F ++ L EN Y RI A N G E Sbjct: 24665 GGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYNFRICAVNIEGAGEH 24724 Query: 2053 LESDEPFKVIPGEGSHADE 2071 + D P VI E A E Sbjct: 24725 V--DVPGSVIAAEKLEAPE 24741 Score = 122 bits (295), Expect = 8e-26 Identities = 90/313 (28%), Positives = 132/313 (42%), Gaps = 8/313 (2%) Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK- 1812 E I+ LD P + +E I+W +GG+ + Y VE ++ + Sbjct: 22260 EKSVIINVKVLDRPGPPDGPISIYGVTSEKCCISWKTPLHDGGAEVSHYIVERRETSRLV 22319 Query: 1813 WKXXXXXXXXX-ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 W +I KL Y FR+ N+ G P SD I +TP + P N Sbjct: 22320 WTVVELKVQTLNLKITKLLPGNEYIFRVIPVNKYGIGEPLESDPVIAANPFVTPEA-PSN 22378 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 VS T S+ + W P ++GGS IT YI+E + +G WT+ S + + Sbjct: 22379 VEVSNITKDSMVITWERPTNDGGSAITGYIVEKRDKEGVRWTRCNKRVVSELRFRVTGLL 22438 Query: 1932 EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 E FR+SAEN GV P+ + + P PP P ++ V V+ W P Sbjct: 22439 EMRSYEFRVSAENAAGVGKPSPPTVYFKAADPVFKPGPPNNP-KVAYVSRASVVLHWSKP 22497 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 +DGG + Y + +VT W M + +F + L E H Y RI A N+IG+ Sbjct: 22498 IYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITETRFEAKKLLEKHEYKFRICAVNKIGV 22557 Query: 2050 SEPLESDEPFKVI 2062 E +D P VI Sbjct: 22558 GE--TADIPGSVI 22568 Score = 119 bits (286), Expect = 1e-24 Identities = 108/430 (25%), Positives = 181/430 (42%), Gaps = 26/430 (6%) Query: 1643 YTIEASNTAGTSS---VEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLE 1697 + + A N G S +E ++ D P P + + E+S+ V ++W+ P +DGG Sbjct: 13870 FRVAAENAVGPSEFCELEDSVLAKDTFGTPGPPYNLTITEVSKTHVDLKWEAPQNDGGRP 13929 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757 + +Y IEK E RW+K Y + + E E F+V A+N G E Sbjct: 13930 VLRYVIEKKEKLGTRWVKSGKTSGPDCHYRVTDVIEGTEVQFQVSAENEAGVGHPSEPTD 13989 Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXX 1816 IV+ P + + I W EKNGGSPII Y +E+ + G +KW Sbjct: 13990 IVVIEDPTGPPSPPQELHITEAARDHICIAWKAPEKNGGSPIIGYHIELCEAGTEKWMRV 14049 Query: 1817 XXXXXXXARIQK-----LSINTTYQFRIYARNEIGTSLPYT-SDDKITIGKTLTPPS--Q 1868 + + + Y FR+ A N +G S P S++ I +P Q Sbjct: 14050 NSRPVKELKYRAGDEEGIVPEKEYTFRVRAVNSVGASEPSDISENVFAIDSDCSPTLDFQ 14109 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 ++ VV E + + P SP + + +K T S H + Sbjct: 14110 TKDLVVVEGEKMHLPI----PFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLE-VP 14164 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988 + D ++++ EN G + T + V +P P + + S+ + SW Sbjct: 14165 SCLHADAGQYKVTLENRNGATSGTINVKV-----IGLPGPCKDIVASEITKSSCKV-SWE 14218 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P++DGG+P+L Y + R+ + +++V + N L + ++DL +N Y R+ A N+IG Sbjct: 14219 PPDYDGGSPILHYVLQRREAGRRTYVKVMSGE-NKLSWPVKDLIQNGEYYFRVRAVNKIG 14277 Query: 2049 LSEPLESDEP 2058 E +E P Sbjct: 14278 GGEFIELRNP 14287 Score = 117 bits (282), Expect = 3e-24 Identities = 111/451 (24%), Positives = 180/451 (39%), Gaps = 26/451 (5%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 +++ L +H ++ ++A N G +S +T K +P P G + + + ++ S+T Sbjct: 18120 MKVTNLIPNHDYQFRVKAENEVGLGEPSKASRPITAKDPIEPPGPPGSLKVVDSTKTSIT 18179 Query: 1685 IEWKPPLDDGGLELTKYAIE---KHEPDNNR-------WIKVADVDRDVET-YCIQKLNE 1733 + W P+ DGG + Y +E K E + + W K + V T Y I L+E Sbjct: 18180 LSWAKPVYDGGAPVIGYLVEMRDKVEMEGEQVRDPEEGWKKCNTSGQLVLTEYTISNLDE 18239 Query: 1734 NCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPS 1791 EY FRV AQN VG A + + K + P + I F + Sbjct: 18240 RQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCPIRLFAT 18299 Query: 1792 EKNGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 + +P + +K + + ++ I + S + ++ + N G Sbjct: 18300 IRGRPAPKVTWKRIGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSGEKAV 18359 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 + K L P ++ T S L W PE++GGSPI NYI+E + V K Sbjct: 18360 FVRV------KVLDTPGPVGGLDATDITKTSCQLAWLPPENDGGSPILNYIVEKREVDRK 18413 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 +WT T I N+ E FR+ A N G+ LP +S L P Sbjct: 18414 TWTN-CTNDLKKTSFKITNLTPGIEYYFRVMAVNKYGIGLPQDSPKSYLATDPKSEPDPP 18472 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 +++ + N W P DGG+ + GY + + + V L + Sbjct: 18473 KKMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQDGQPEDKWTSYSVVKDLTIVVAG 18532 Query: 2031 LSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 L EN Y R+ ARN IG S E++ F+V Sbjct: 18533 LKENTKYRFRVAARNAIGCSLAREAEGIFEV 18563 Score = 115 bits (276), Expect = 2e-23 Identities = 99/435 (22%), Positives = 175/435 (40%), Gaps = 18/435 (4%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E + P + L+ +G +V ECQ+ G+P P I WFR+ I+ S DFQ+ Y + Sbjct: 736 KEPVVPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITY-EK 794 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--------PLSDHGSEMTVXX 615 + A L+IRE F ED+G FTC A + AG S++ L+V+ ++ + V Sbjct: 795 SYARLMIREAFAEDSGRFTCTATSEAGTISTSCYLLVKVSEEIESREEITIQEKQTVVEA 854 Query: 616 XXXXXXXXXXADILEGIP--PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 + G P P F KKP Q + EG ++ C++ P+P I W G Sbjct: 855 KDETMSEISSVSVDTGAPAAPFFVKKPVVQKLVEGGSVVFVCQIGGSPKPHIYWKKSGVP 914 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL----KIKT 729 + V+ D C L+I+ G YT+ A N+ GE S L + + Sbjct: 915 LTTGYRYRVSHNKDTG-ECK-LEISMTFADDAGEYTIFAKNQHGETSASTSLLEEEEFEA 972 Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 K+ + +V++ + + VV + + + + + T I Sbjct: 973 YMKKQDVTYVTEVTAMVQEPKVADVPPVVVSEYEKELIQRRMAQQTQMMQTFISETEFQI 1032 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 + ++ K +++ + LK E + E + + E A F + + E Sbjct: 1033 SAIERKIIQEIEIRILKITYQELVIEDGEEMVI-NVAEHEAVASSFSTPVKSYRILEGMG 1091 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + ++ P+P I WY++ + I + + V D G Y AS Sbjct: 1092 VTFHCKMGGKPLPKIAWYKDGKRIKHGGRYQMEVLQDGRASLRLPVVLPEDEGIYTAFAS 1151 Query: 910 NSAGKSSHGARVTID 924 N G + ++ ++ Sbjct: 1152 NMKGNAVSSGKLYVE 1166 Score = 112 bits (269), Expect = 1e-22 Identities = 78/302 (25%), Positives = 122/302 (40%), Gaps = 7/302 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822 LD P +D SV +W P +K+GG+ + Y VE + + W Sbjct: 29462 LDKPGVPVGPMKIEEVDATSVTCSWEPPQKDGGANVSGYIVEQRDAHRPGWMSVSESVTR 29521 Query: 1823 XA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + +L T Y FR+ A N G + + + T P P + + + Sbjct: 29522 PVFKFTRLVEGTEYVFRVAATNRFGIG-GFLQSEVVECKSVKTVPGAPSTPEILDVSHDG 29580 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 +TL WT PE NGGS I YIIE K W I ++ + + E E +R++ Sbjct: 29581 MTLTWTPPEDNGGSTIAGYIIERKEAGSDRWLSINKNPVTMTRYRATGLIEGLEYEYRVT 29640 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLL 1999 A N+ G P+ + + PP PL R+ + V +W PE +GGA + Sbjct: 29641 AINSRGTGKPSANSKPTIAMDPI--EPPGIPLNPRVTDTTRTSVSLAWSPPEEEGGAAVT 29698 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 GY I ++ V + W + ++ + + + Y R+ A N G EP E Sbjct: 29699 GYLIEMQKVDQVEWTKCNTTPTKICEYTLTHMPQGAEYKFRVMACNAGGAGEPAEIPGVV 29758 Query: 2060 KV 2061 KV Sbjct: 29759 KV 29760 Score = 111 bits (267), Expect = 2e-22 Identities = 136/593 (22%), Positives = 229/593 (38%), Gaps = 38/593 (6%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q + P F L+P +G T+ C V G P +I W + + S + ++ + D Sbjct: 7504 QKVPPSFDLPLKPVTVNEGETLTLSCHVRGSPPLKIQWMKDRRELSSSANTKITF-VDGT 7562 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 ATL + V D+G + C A N AG AP E+ Sbjct: 7563 ATLEMTRVSKTDSGDYLCKATNEAGNKPGAPAPAQAAP--SPPQEVKKFDNLFFIEVPKS 7620 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 I+E TF K G D P P++ W+ KG+ ++IE Sbjct: 7621 VHIVEKGTATFIAK-------VGGD----------PIPNVKWM-KGKWRQMTHGGRISIE 7662 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + ++I V K G Y VA N+ GE L + ++ ++++ K+ Sbjct: 7663 QKGQE--AKMEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKETTVEMVKLKKTPS 7720 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYT 804 ++ +V R + + K + T G +I LK +K + G Sbjct: 7721 KQKSPKEEKDIDIVELLR-NVDPKEYEKYARMYGITDFRGLLQAIEFLKKEKELESGRPE 7779 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVP 862 + E + + ++ + E EP Q TVK++ + ++ P Sbjct: 7780 GEIVGRESEEDLAKLVADLQKRMEQTEPVTVARDITDQTTTVKKEAVFECEIKI-NYPEI 7838 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +++WY+ + + + G+ L I + + D G+Y+ V G A++T Sbjct: 7839 TLSWYKGTQKLDSGDKYDIKIVGDRHILKIKDCQTR-DEGNYRIV----CGPHISSAKLT 7893 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRX 981 + +V K +Q +EG+T L CQ S V T+W+ N K + Sbjct: 7894 VLEAEVE--KPMQ-DVAGKEGQTCTLTCQLSVPNVKTQWFRNGKLLEPHSRYTCAVANYT 7950 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G C K+ ET+ L ++ F +++Q+ V+E A E E++ Sbjct: 7951 QKLSIKDVRPEDQGEYTCKYKNLETTANLWIEAEQIHFTKRIQNIVVREHQSATFECEVS 8010 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 + A V W +D +K + KY F G + IRN S DEG YS I+R E Sbjct: 8011 FDNAVVTWYKDTWELK-ESPKYTFRSEGRRHFMIIRNVSSADEGVYSVIVRLE 8062 Score = 109 bits (262), Expect = 8e-22 Identities = 108/451 (23%), Positives = 199/451 (44%), Gaps = 48/451 (10%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 ++P P + P+ + ++ +G + +F+C+V G ITW+ + IK S Sbjct: 3103 EVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLT-ITWYCKDKEIKQS 3161 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEM 611 F++ D+N L I V+PED G +TCVA+N+AG S + L V E + D+ S+ Sbjct: 3162 DIFRVSQFDEN-CQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVDGETEVMDYSSKF 3220 Query: 612 --TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669 D + G P+F + + V G + IP+P+I+W Sbjct: 3221 PPQATSSPLTSIKTIQKDAI-GQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFH 3279 Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 + I P +N V D + L I + G YT AVN GEA+ L + Sbjct: 3280 NQQPIKPTKN--VVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAV-- 3335 Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 +E +V E +++ I + + ++ VK T+ + +T+S Sbjct: 3336 -TEEVTRVREEIEAKIEEEVKEF------------------SSLTVK---TEEEEETYST 3373 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 ++ P+K K TL+ + + +S E+P E+ P E+T+ E + Sbjct: 3374 SLHLPEKSK-----TLELKPEQKRFSSSLERKREKPVFESKLTP------AEVTIGE--S 3420 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 ++ V+ P P + W+ N + I+ S T + + L+IT V + + G+Y C AS Sbjct: 3421 VRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYSLIITKVKKDYE-GEYSCTAS 3479 Query: 910 NSAGKSSHGARVTIDVEKVTFV-KHLQKSYE 939 N G+++ + +++ +++ K ++K ++ Sbjct: 3480 NRFGQTTCKTILKVELSQLSAAEKWVEKMFK 3510 Score = 109 bits (262), Expect = 8e-22 Identities = 59/203 (29%), Positives = 100/203 (49%), Gaps = 3/203 (1%) Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 K + P +N V ++ +++ W EPES+GGS I Y++E + VK K+WT Sbjct: 12801 KVIDVPGPVKNLQVVDTADGEISIAWEEPESDGGSKILAYVVERRDVKRKTWTLATDCAD 12860 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVG 1979 S E+ + ++ + +FR+ A N VG E+ ++V+ + VP P + + V Sbjct: 12861 ST-EYTVTGLQRDSKYLFRVCARNRVGSGPNVETDKAVQAKNKFDVPDAPQNVI-VGNVN 12918 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 SW P +DGG+ + Y I +RD T +W V + I D+ EN Y+ Sbjct: 12919 KFGATVSWEPPLFDGGSEITSYIIELRDRTSVVWAPVMVTKPHERSAIINDVIENKEYIF 12978 Query: 2040 RIYARNEIGLSEPLESDEPFKVI 2062 R+ A N+ G+ +P + P K++ Sbjct: 12979 RVKAENKAGIGKPSAATNPVKIM 13001 Score = 109 bits (262), Expect = 8e-22 Identities = 89/290 (30%), Positives = 131/290 (45%), Gaps = 19/290 (6%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ------EGKKW-KXXXXXXXXXARIQKLSI 1831 I ES ++W GGS + +Y VE+K E +W + + L Sbjct: 15279 IKAESCNLSWDAPLDIGGSELTNYIVEMKDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVT 15338 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 Y+FR+ A N+ G S +++ + I P P ++E + + L W P+ Sbjct: 15339 GGNYKFRVKAENKYGISEACETEE-VEIKDPSALPGPPEKVTIAERSKTHMLLTWEPPKD 15397 Query: 1892 NGGSPITNYIIEFKTVKGKS-WTKIVTV-----GGSVHEHCIENIKEKDEIIFRISAENT 1945 +GGS IT Y +E K KG S W+++ + G E+ + + E E FR A N+ Sbjct: 15398 SGGSMITGYWLE-KREKGTSYWSRVNKILVSKRGMKGWEYQVTRLFEGVEYEFRAMACNS 15456 Query: 1946 VGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 G+ P+ S+S + T PS P AP EI + V +W P DGG P+ GY I Sbjct: 15457 AGIGPPSAISESAVADDPLTPPSMPAAP-EIADKTKHSVTLAWTPPAKDGGRPIKGYIIE 15515 Query: 2005 IRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 I+D + W V + + F I +L E Y RI A NEIG SEP Sbjct: 15516 IQDEGTSEWARVNDAENLHPSTVFTIPNLPELKKYRFRIIAVNEIGESEP 15565 Score = 109 bits (261), Expect = 1e-21 Identities = 101/439 (23%), Positives = 184/439 (41%), Gaps = 26/439 (5%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGP---VIMREISRESVTI 1685 R+ ++ ++ + A N AG S + V + P+ P P + + E +R+ + I Sbjct: 13959 RVTDVIEGTEVQFQVSAENEAGVGHPSEPTDIVVIEDPTGPPSPPQELHITEAARDHICI 14018 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC-----EYMFR 1740 WK P +GG + Y IE E +W++V R V+ + +E EY FR Sbjct: 14019 AWKAPEKNGGSPIIGYHIELCEAGTEKWMRVNS--RPVKELKYRAGDEEGIVPEKEYTFR 14076 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A N VG SE + V D P+ ++ E +++ P I Sbjct: 14077 VRAVNSVGASEPSDISENVFAIDSDCSPTLDFQTKDLVVVEGEKMHLP-IPFRAVPSPKI 14135 Query: 1800 IDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 +K E+K + + + + Q+++ N G + I Sbjct: 14136 TWHKDGNEMKADDRTF-FRAEYTSCHLEVPSCLHADAGQYKVTLENRNGAT-----SGTI 14189 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 + K + P ++ V SE T S + W P+ +GGSPI +Y+++ + +++ K+++ Sbjct: 14190 NV-KVIGLPGPCKDIVASEITKSSCKVSWEPPDYDGGSPILHYVLQRREAGRRTYVKVMS 14248 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIR 1976 G + ++++ + E FR+ A N +G E ++ V E P PP +E Sbjct: 14249 -GENKLSWPVKDLIQNGEYYFRVRAVNKIGGGEFIELRNPVIAEDQKQRPDPP-VDVETH 14306 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 S V +W P +DGG+ ++GY + + + V L + ++ L+ Sbjct: 14307 NPTSESVTLTWKPPMYDGGSKIMGYILEKMMKGEENFQRCNDFLVPVLSYTVKGLTHEKQ 14366 Query: 2037 YMIRIYARNEIGLSEPLES 2055 Y R+ A N G+S+P S Sbjct: 14367 YQFRVRAENAAGVSDPSRS 14385 Score = 108 bits (259), Expect = 2e-21 Identities = 137/586 (23%), Positives = 236/586 (40%), Gaps = 65/586 (11%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 +K K V E EC + P WL G EI E + ++ +H LK Sbjct: 2658 TKPLKNLEVPETHVATFECEVSHFNVPS-TWLKNGVEIEMSEKFRIVVQGKLHQ----LK 2712 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 I N + YT V N + A+L + P + LK + ++ +++ Sbjct: 2713 IMNTSRDDSAEYTFVCGNDKVSATLTV---------SPVLITSMLKDLNAQEKDTITFEV 2763 Query: 757 QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 V T W KN +++ T++ +HS+TI + D G Y A G Sbjct: 2764 -TVNYEGITYKWLKNGVEIRSSDRCQTRTKQLSHSLTI-RNVHFGDVGDYKFVA----GS 2817 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 AET+A + VE E F ++I V EK ++ P +TW ++ + + Sbjct: 2818 AETAAKLFVEARVIE------FTKHIKDIKVTEKKKAVFECELSE-PNVQVTWMKDGQEL 2870 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 SE + + L+I V D+G+Y VA +S K A +T++ + V + Sbjct: 2871 ELSERYKVSTERHVHRLMIQTVRMS-DAGEYSVVAGSSVSK----ANLTVEGKDVRISEP 2925 Query: 934 LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS-GMDHR---EIIQEGRXXXXXXXX 988 +K E + E + + + +W N EI +D R II+ + Sbjct: 2926 AEKEITVLEKQRSTFEFEVNEDDIEGRWLRNGVEIQFSVDQRFNYAIIR--KIHRLTITE 2983 Query: 989 XXXXDVGVIKCIV-KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETAD 1046 D G I K++ T+ V P+ IR +Q V+ A VE+ Sbjct: 2984 TYRSDAGEYTFIAGKNRSIVTLHVNIPEPPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQ 3043 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEV 1100 V W ++ + + K F + G+ L + D +Y+C +++ S + V Sbjct: 3044 VSWYKNSQALS-SGFKCKFLREGNEHTLLLIEVFPEDAAQYNCEAKNDYGVATSSASLNV 3102 Query: 1101 TVVEL----------PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150 V E+ PP ++T +QN N+G A F+ ++ D + W+ EI+ S+ Sbjct: 3103 EVPEVVSPDTGAPLSPPVVLTPIQNTSANEGQSARFQCRVSGEDLTITWYCKDKEIKQSD 3162 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVE 1192 +++ + +L+I +D GEY+C NS C+A+L V+ Sbjct: 3163 IFRVSQFDENCQLEITRVYPEDEGEYTCVARNSAGMVSCSALLKVD 3208 Score = 107 bits (257), Expect = 3e-21 Identities = 86/319 (26%), Positives = 136/319 (42%), Gaps = 13/319 (4%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 + + A NP GF++ + + + LD P + E ++W P +GG Sbjct: 21168 YTLTASNPGGFAKFVFNVKV-----LDRPGPPEGPLHVTDMTVEKCVLSWLPPLHDGGGK 21222 Query: 1799 IIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 I Y ++ ++ + W ++ KL Y FR+ A N+ G P S+ Sbjct: 21223 IEYYIIQRRETSRLTWTNVATDLQVNRYKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPA 21282 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 + + P P+ V+ T S+ + W PE NGGS I YIIE + G W K Sbjct: 21283 VATNPYV-PSDPPQAPEVTAITKDSMVVCWGHPEYNGGSSINTYIIERRDKTGLRWVKCN 21341 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV--PSPPTAPLE 1974 + + + E +RI AEN G+S P+ S S + T+ P PP P Sbjct: 21342 KRTVTDLRFKVSGLTPGHEYEYRILAENAAGLSAPSPS-SPFYKACDTIFQPGPPGNPRV 21400 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV-DVNTLKFNIRDLSE 2033 + S+I + +W P +DGG+ + GY + + W V + + F I +L+E Sbjct: 21401 LDTTKSSITI-AWNKPVYDGGSDITGYIVETCLPEEDEWTIVTPMAGLTATSFTITNLTE 21459 Query: 2034 NHTYMIRIYARNEIGLSEP 2052 N Y I I A N G+ EP Sbjct: 21460 NQEYKINISALNCEGVGEP 21478 Score = 103 bits (247), Expect = 5e-20 Identities = 96/379 (25%), Positives = 158/379 (41%), Gaps = 23/379 (6%) Query: 523 DGSTVQFECQVEGYPR-PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G V+F C +E Y R ++TW+ + + S +++ Y + VA++ ++++ D G + Sbjct: 31213 EGGHVRFVCCIENYDRNTEVTWYFGSRKLTASHKYEITYAN-GVASIYVKDIEECDDGLY 31271 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 C + ++ EL VE S + + IL+ PP F+ Sbjct: 31272 RCKVVSEDREDNAYAELFVETVRSFREYYLG-RSLKKPRRRIDKSKILQR-PPEFTLPLF 31329 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 + G D+ + PEP + WL G I PD SD +Y L I NV Sbjct: 31330 NRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPK-KYTFTSDKGLY--QLMIHNVD 31386 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR----QGESVILSAQ 757 + YTVVA N+ GE S L + + K ++ +G+SV + Sbjct: 31387 LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLR 31446 Query: 758 VVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 V G P PT+ W KN KP++ P + D D + I ++ ++D G Y + A N+ G Sbjct: 31447 VSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVD-YFILHIRETLIEDSGTYRVTATNTAGS 31505 Query: 814 AETSAVITVEEPT------EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 A A + VE T + E +++ E T+K V NPV Sbjct: 31506 ASCQATLKVERLTYTRREFKSEEERHIYVRNQIEKTLKMAQEFSKAEVVALNPVAQEALK 31565 Query: 868 RNNEIISPSETITQNFDGE 886 E+ P+ + T++ GE Sbjct: 31566 EAAELYKPAVS-TKHVQGE 31583 Score = 103 bits (246), Expect = 7e-20 Identities = 106/426 (24%), Positives = 174/426 (40%), Gaps = 28/426 (6%) Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 ++KP P P I+R+S+ + W+ P DDGG ++ + +EK + + RW K + Sbjct: 24534 FNKPGPPSTPEASA-ITRDSIVLTWERPEDDGGSQIDGFVLEKRDKEGIRWTKCNKKRLN 24592 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + L E Y FRV A+N G SEP A D D+ Sbjct: 24593 DLRFRATGLTEGHFYEFRVSAENAAGVGTP--SEPSEYYKACDATYPPGPPNNPKVTDHS 24650 Query: 1783 S--VYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR---IQKLSINTTYQ 1836 S V + W +GG+P+ Y VE K + +W A ++KL N Y Sbjct: 24651 STTVSLAWSRPIYDGGAPVSGYIVEAKDINEDEWTVCTPPTGVQATHFTVKKLKENAEYN 24710 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FRI A N G + + L P + + + + + + G P Sbjct: 24711 FRICAVNIEGAGEHVDVPGSVIAAEKLEAPEIELDADLRKCVTVRASATLRLFVTIRGRP 24770 Query: 1897 ITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 +++K G + + V GS I+N+ D + ++ EN +G ++S Sbjct: 24771 EPE--VKWKKADGTLPERAQIEVTGSYTGLVIDNVNRFDTGKYVLTLENNIG----SKSA 24824 Query: 1956 SVRLEKHATVPSPPTAPL--EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 V ++ V P+AP+ E++ V + V W P+ DGGA + Y + R+ + + Sbjct: 24825 FVNVK----VLDSPSAPVNFEVKDVKRDSVQLQWEPPQIDGGAKITHYIVEKRESKRLAF 24880 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 + V + DL E Y R+ A NE+G+ P E+ E K+ S A P Sbjct: 24881 TSITNNCVRN-SIRVDDLQEGGLYHFRVLAVNELGVGLPAETTEAVKI-----SQAPLPP 24934 Query: 2074 GEQTEV 2079 G+ T + Sbjct: 24935 GKITVI 24940 Score = 101 bits (243), Expect = 2e-19 Identities = 112/381 (29%), Positives = 162/381 (42%), Gaps = 75/381 (19%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568 P + ++P G +F +V G P+PQ++W++ + + S F+ + + N TL Sbjct: 3013 PQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQAL--SSGFKCKFLREGNEHTL 3070 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXX 625 ++ EVFPEDA + C AKN G A+S+ L VE P D G+ ++ Sbjct: 3071 LLIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLS------------- 3117 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 PP + +EG +CR V+ + I W K +EI + V Sbjct: 3118 -------PPVVLTPIQNTSANEGQSARFQCR-VSGEDLTITWYCKDKEIKQSDIFRV--- 3166 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------PPQV 737 S C L+IT V EG YT VA N G S +LK+ GE E PPQ Sbjct: 3167 SQFDENCQ-LEITRVYPEDEGEYTCVARNSAGMVSCSALLKV-DGETEVMDYSSKFPPQA 3224 Query: 738 ----------------------IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 +P+ S +V GE A V G P+P I+W N +P+ Sbjct: 3225 TSSPLTSIKTIQKDAIGQKPSFFQPIMSSVVAHGEVARFHACVSGIPKPEISWFHNQQPI 3284 Query: 776 KALPTKS-----DGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITV-EEPT-- 826 K PTK+ D T++ T++ + G YT KA N G A SA + V EE T Sbjct: 3285 K--PTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIRGEAACSANLAVTEEVTRV 3342 Query: 827 --EENAEPPLFINRFQEITVK 845 E A+ + F +TVK Sbjct: 3343 REEIEAKIEEEVKEFSSLTVK 3363 Score = 100 bits (239), Expect = 5e-19 Identities = 69/231 (29%), Positives = 115/231 (49%), Gaps = 17/231 (7%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTK--SDGDTHS 788 + P +PL+S++ +G + AQV GNP P ++W ++ + + A LP S D + Sbjct: 4 QAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRA 63 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + ++ G ++++A N G A ++A + V T E A PP FI R Q +TV++ Sbjct: 64 VLMIPAVTAAHSGRFSVRATNGAGQATSTAELLV---TAETA-PPNFIQRLQSLTVRQGS 119 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 ++L RVT P P + +YR I S DG+ L+I E DSG Y A Sbjct: 120 QVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPE-DSGTYSVSA 178 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959 SNS+G+++ A + + E +++ ++ KT+I Q S T T+ Sbjct: 179 SNSSGRATSTAELLVQGE--------EEAVPAKKSKTIISASQISQTRQTR 221 Score = 99.1 bits (236), Expect = 1e-18 Identities = 155/752 (20%), Positives = 268/752 (35%), Gaps = 48/752 (6%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 S T+K + + +++R EN G +D + ++ +P + S + Sbjct: 14355 SYTVKGLTHEKQYQFRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKR 14414 Query: 1404 PE----NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 E + S Y + + + T W + + I+ K + E Sbjct: 14415 GEEIRLDANISGFPYPQITWMRNNATIWPEPLK-KRPERPIKKKKEKEEKKEEGAEKKEA 14473 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 D E E + KE K + EK + EP E P+ ++ Sbjct: 14474 DAEKKEEDKEAKEEDKEKKEEKKEEEKEKEKEVEEPEE-------------PEEEYHPSL 14520 Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISN 1577 + T ++ + + NDHG SC V I P + Sbjct: 14521 NERLTIESKRKGESYIIIKDTIRGDHGVFTIKVENDHGTASASCEVNILDTPGPPVNFKF 14580 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 E+I+ K+ + +W G I + N +T+ + + +L Sbjct: 14581 EEIR-KNSILCKWDPPLDDGGSEILNYILERKDNSKAELGWITVTSILRGCKFLVPKLIE 14639 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 + + A N G +T V +D P PE P I ++++ S+ + W P + Sbjct: 14640 GKEYLFRVTAENKYGPGKPCITKPVIARNPFDPPDAPEKPEI-KDVTASSMCVTWLEP-N 14697 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 D G + Y +EK E ++ W +V + D+E ++ L E Y+FRV A+N G + Sbjct: 14698 DNGSAIEGYWVEKREINSTHWARVNRTMVPDLEIN-VEGLLEGLTYIFRVCAENIAGPGK 14756 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNE--SVYITWFPSEKNGGSPIIDYKVEIKQE 1809 S P KTA P +D S+ I W P NGG+ + Y V+ Sbjct: 14757 F--SPPSEPKTA-QAPIMPPGPPIPRIVDTSDYSIDIEWDPPADNGGAEVFGYHVDKLVA 14813 Query: 1810 GKK-WKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 G K W + Y R+ A N G P +D I P Sbjct: 14814 GTKDWSRATERPHKTRTFTVYGVREGAKYIVRVVAINCAGEGEPGLTDAVIVRNPAEVPV 14873 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 + V + R+ + G P + + K ++ G Sbjct: 14874 IELDISVRNGVVVRAGEMLRIPAHVTGRPPPSLKWTKDDGDLEKDRMEVEEAGQD-STVV 14932 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I+ K D ++I A N G+ +S R+E VP P L+ +V ++M + Sbjct: 14933 IKTTKRSDHGKYQIQAANPSGI----KSAWTRVEV-MDVPGP-VLDLKPVVVTRKLMMLN 14986 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ DGG+ + G+ I R+ W + ++ + K I + E Y+ R+ A+N+ Sbjct: 14987 WSDPDDDGGSDVTGFIIERREPKMHTWRQ--PIETPSSKCEIVGIIEGQEYIFRVVAKNK 15044 Query: 2047 IGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078 G P++ P + + +G E TE Sbjct: 15045 YGCGPPVDLG-PIRAVDPQGPPTSPEKFHYTE 15075 Score = 93.5 bits (222), Expect = 6e-17 Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 12/184 (6%) Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSID--SKSASLTIKKVE 1351 R+++ + + + P P EW+ + +I+K ID + L+I V Sbjct: 15179 RVRKNEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVT 15238 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G Y + N G + V +LD+P+PP + I + S N+ WD P + G S Sbjct: 15239 RLDKGTYTVTASNRLGTLSHSVTVEVLDRPTPPRNVAVSSIKAESCNLSWDAPLDIGGSE 15298 Query: 1412 IIYYVVEYQEI-----DTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + Y+VE +++ + EW+ V K+I + + + NL T +Y+FR A N+ IS+A Sbjct: 15299 LTNYIVEMKDLNVEDPEKAEWVQVTKSIIEKRYGVWNLVTGGNYKFRVKAENKYGISEAC 15358 Query: 1466 ETTE 1469 ET E Sbjct: 15359 ETEE 15362 Score = 90.2 bits (214), Expect = 5e-16 Identities = 58/202 (28%), Positives = 95/202 (47%), Gaps = 8/202 (3%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTK 781 +K K E P + E +K + GES IL+ Q++G P P I W + K + + Sbjct: 30156 IKTKLSVGEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMS 30215 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 SDG HS++++ ++ +DEG+YT +A N G ETS + ++ + + PL + Sbjct: 30216 SDGRNHSLSVMTDEQ-EDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGFPLKEKYYAG 30274 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + + + R P+P I W+ + ++PSE + LVI NV + ++ Sbjct: 30275 CGTSLRLHVVYIGR----PIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNA 30330 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G YK SN G RV I Sbjct: 30331 GRYKVQLSNKFGTVDTVLRVEI 30352 Score = 89.4 bits (212), Expect = 9e-16 Identities = 95/367 (25%), Positives = 153/367 (41%), Gaps = 33/367 (8%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 +E +++A F ++ +G V F C++ G P P+I W++ IK +QM Sbjct: 1068 AEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWYKDGKRIKHGGRYQMEVLQ 1127 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH----GSEMTVXXXXX 618 D A+L + V PED G +T A N G A S+ +L VE+ + +E Sbjct: 1128 DGRASLRLPVVLPEDEGIYTAFASNMKGNAVSSGKLYVESTAAAQPYYPQAEAVRRVQST 1187 Query: 619 XXXXXXXADILEGIPPTFS-KKPKAQYVDEGSDILLE--CRLVAIPEPDIAWLFKGEEIV 675 A G P S + A+ +D+ + LE + V + +P +G+ Sbjct: 1188 SPMSARSASYSPGRSPARSVSRSPARRLDDTDESQLERLYKPVFVQKPSSFRCSEGQTAR 1247 Query: 676 PDENISVAIESDMHMYCSVLKITN-----VKKFQEGTYTVVAV---------------NR 715 D + D + S ++ N + ++GT +++ V NR Sbjct: 1248 FDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNR 1307 Query: 716 EGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN-- 772 G+ ++ + L ++ E PQ IE LK++ V++G V L+ + +GNP P I W KN+ Sbjct: 1308 AGKTTVSMTLTVEAKENLVRPQFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWLKNSDI 1367 Query: 773 -KPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSAVITVE-EPTEEN 829 P K K +G P+ D YT A N G T + VE E TE Sbjct: 1368 ISPHKYPHIKIEGAKGQAHFQIPQTSGSDSAWYTATAINKAGRDTTRCRVNVEVEYTEPV 1427 Query: 830 AEPPLFI 836 E L I Sbjct: 1428 PERRLII 1434 Score = 89.4 bits (212), Expect = 9e-16 Identities = 59/198 (29%), Positives = 94/198 (47%), Gaps = 10/198 (5%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSI 789 P ++ S +G++ +VVG P P W + + V + K DG T S+ Sbjct: 1229 PVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDG-TQSM 1287 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 ++ P +D G +T+ A+N G S +TVE +EN P FI + + I+VKE Sbjct: 1288 IVV-PAMPQDSGEWTVVAQNRAGKTTVSMTLTVE--AKENLVRPQFIEKLKNISVKEGSL 1344 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI-TNVDSEIDSGDYKCVA 908 ++L + NP+P I W +N++IISP + +G + S DS Y A Sbjct: 1345 VELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGSDSAWYTATA 1404 Query: 909 SNSAGKSSHGARVTIDVE 926 N AG+ + RV ++VE Sbjct: 1405 INKAGRDTTRCRVNVEVE 1422 Score = 89.4 bits (212), Expect = 9e-16 Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 5/170 (2%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGI 1357 K G+ + L D P+P +W ++K + +ID+K ++L+I K + D Sbjct: 13418 KAGTKIELPADITGKPEPKVKWTKADLVLKP--DDRITIDTKPGHSTLSIAKTKRDDTAT 13475 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 Y + N+ G A ++V ILDKP PP +I EI + S + W+ P + G S + Y+V Sbjct: 13476 YIIEAVNSSGRATATVDVNILDKPGPPAAFDISEITNESCVLAWNPPRDDGGSKVTNYIV 13535 Query: 1418 EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466 E + +D+ W + + K T L Y FR YA N+ I +E Sbjct: 13536 ERKAVDSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVYAENQFGIGAPAE 13585 Score = 85.4 bits (202), Expect = 2e-14 Identities = 61/232 (26%), Positives = 99/232 (42%), Gaps = 9/232 (3%) Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK-----VEVVE--FPPKIVD 1292 +K+T S VK T+++ E+ + + +A + + EV E PKI+ Sbjct: 18515 DKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEVKEQLMAPKIIV 18574 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 + + GS + + P P +W S I ++ L +K V Sbjct: 18575 SD-VVTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPTTSLLMVKDVTR 18633 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNST 1411 D+G Y L EN+ + + + I+D P PP P ILE+D + + WD P G S Sbjct: 18634 KDSGYYSLSAENSTAKVNQIIRIIIMDIPGPPQGPLQILEVDVDACTLAWDTPAEDGGSN 18693 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 I Y+VE ++ +W++ + TKT + L Y FR A N IS+ Sbjct: 18694 ITNYIVEKCDVTRGDWVTAVSCTKTSCRVGKLTCGKEYGFRVRAENRFGISE 18745 Score = 85.0 bits (201), Expect = 2e-14 Identities = 66/249 (26%), Positives = 109/249 (43%), Gaps = 20/249 (8%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTS---EEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 +E Y+ L K +L +K S E + P+F KL P G +V+F Sbjct: 3367 EEETYSTSLHLPEKSKTLELKPEQKRFSSSLERKREKPVFESKLTPAEVTIGESVRFTVT 3426 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 V G+P+P++ WF I S + + D + L+I +V + G ++C A N F Sbjct: 3427 VSGFPKPKVQWFHNGKAITSSSIYTFVEERDEYS-LIITKVKKDYEGEYSCTASNR--FG 3483 Query: 593 SSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 +T + I++ LS +E V + G PP F+ + + EGS++ Sbjct: 3484 QTTCKTILKVELSQLSAAEKWVEKMFK----------IPGQPPCFTTQIQPVQCVEGSEV 3533 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 + ++ P PD+ W +I + SV D + L ++N+++ G YT Sbjct: 3534 KFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGF---LIMSNIQQRDSGLYTCK 3590 Query: 712 AVNREGEAS 720 AVN GEAS Sbjct: 3591 AVNPFGEAS 3599 Score = 82.6 bits (195), Expect = 1e-13 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 11/203 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 PTF++ ++ EGS E ++ P P+++W G+ + I SD Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGR--- 62 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +VL I V G ++V A N G+A+ L + T E PP I+ L+S+ VRQG V Sbjct: 63 AVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLV-TAETAPPNFIQRLQSLTVRQGSQV 121 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L +V G P P + + + +++ DGD +S+ I + +D G Y++ A N Sbjct: 122 RLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFP-EDSGTYSVSASN 180 Query: 810 SEGIAETSAVITVEEPTEENAEP 832 S G A ++A + V+ EE A P Sbjct: 181 SSGRATSTAELLVQ--GEEEAVP 201 Score = 82.6 bits (195), Expect = 1e-13 Identities = 93/417 (22%), Positives = 168/417 (40%), Gaps = 29/417 (6%) Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758 +Y +E + ++ W + + V+ + L E EY FRVIA N G + + +E + Sbjct: 19845 RYYVEFKDRNSLMWKRASKTQLRVKECRVTGLVEGLEYEFRVIAINVAGLGKPSRTTESL 19904 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXX 1817 V +D P + SV + W + +GG + Y VE ++ GK W Sbjct: 19905 VALDPIDPPG----KPDVINVTRNSVTLMWTAPKYDGGHKLTGYMVEKLEHPGKTWMKAN 19960 Query: 1818 XXXXXXA--RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVV 1874 + L T +FRI A+N G S P + + + PP+ + + Sbjct: 19961 HVNVQSCAYTVTDLQEGCTCEFRIRAKNAAGAISAPSETTEPLVCKDEYEPPTITIDPEM 20020 Query: 1875 SESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH--CIENI 1930 + + T+ T G P T + K + + IV + + I+ Sbjct: 20021 KDGVTVKAGGTIVITASSILGKPPPT--AVWSKAGREFKSSDIVQISSTPTSSTLSIKYA 20078 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 K+ + I+A N G+ + + V++ K VP PP P+E V + +W P Sbjct: 20079 SRKNTGEYTITASNPFGI----KDEKVKV-KVLDVPGPP-GPIEASSVSAEKCTLTWLPP 20132 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 E DGG + Y + R+ ++ +W ++ + +V ++ L + + Y+ R+ A N+ G Sbjct: 20133 EEDGGCSIKSYILEKRETSRLLWTKLAE-NVMDCRYVASKLIKGNEYIFRVSAVNQYGTG 20191 Query: 2051 EPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREH-NMDADIRSY 2106 + +S P K++ G PG ++ W R + +DIR Y Sbjct: 20192 DVTQSG-PVKMVDSFG-----PPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGY 20242 Score = 81.4 bits (192), Expect = 2e-13 Identities = 66/236 (27%), Positives = 106/236 (44%), Gaps = 21/236 (8%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTH 787 ++E P L V GESV + V G P+P + W N K + + + + D + Sbjct: 3400 KREKPVFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAITSSSIYTFVEERDEY 3459 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE------------PPLF 835 S+ I K KK EG Y+ A N G ++ VE AE PP F Sbjct: 3460 SLIITKVKK-DYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCF 3518 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVIT 893 + Q + E +K +VT P P + W++ N I S+T + N DG L+++ Sbjct: 3519 TTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGF-LIMS 3577 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 N+ DSG Y C A N G++S A + + ++V+ V H Q+ + ++ V ++ Sbjct: 3578 NIQQR-DSGLYTCKAVNPFGEASCSAELIVFHKQVS-VFHKQQLVQEQKSYKVSMK 3631 Score = 80.6 bits (190), Expect = 4e-13 Identities = 58/215 (26%), Positives = 98/215 (45%), Gaps = 7/215 (3%) Query: 1291 VDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 +D++ ++ + G + L + ++A P P W + +K T + S L + Sbjct: 14106 LDFQTKDLVVVEGEKMHLPIPFRAVPSPKITWHKDGNEMKADDRTFFRAEYTSCHLEVPS 14165 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 + DAG YK+ LEN G +NV ++ P P EI SS + W+ P+ G Sbjct: 14166 CLHADAGQYKVTLENRNGATSGTINVKVIGLPGPCKDIVASEITKSSCKVSWEPPDYDGG 14225 Query: 1410 STIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 S I++YV++ +E ++ V K +++L N Y FR AVN++ + E Sbjct: 14226 SPILHYVLQRREAGRRTYVKVMSGENKLSWPVKDLIQNGEYYFRVRAVNKIGGGEFIELR 14285 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELT 1502 VI E + Q P + P+ T P +E + LT Sbjct: 14286 N--PVIAEDQKQRP--DPPVDVETHNPTSESVTLT 14316 Score = 80.6 bits (190), Expect = 4e-13 Identities = 60/249 (24%), Positives = 114/249 (45%), Gaps = 19/249 (7%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTH 787 + PP+ PL + GE V + +P P++TW K +K P K SD + Sbjct: 31319 QRPPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPKKYTFTSDKGLY 31378 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKE 846 + I + D+ YT+ A N G A + V E+ P+F I E Sbjct: 31379 QLMIHNVD-LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVE 31437 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEI--DSG 902 +++ RV+ P P++ W +N + + P + Q E+++ I ++ + DSG Sbjct: 31438 GQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQ----EDVDYFILHIRETLIEDSG 31493 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH 962 Y+ A+N+AG +S + T+ VE++T+ + + +++EE + + + Q T+ Sbjct: 31494 TYRVTATNTAGSAS--CQATLKVERLTYTR---REFKSEEERHIYVRNQIEKTLKMAQEF 31548 Query: 963 NKKEISGMD 971 +K E+ ++ Sbjct: 31549 SKAEVVALN 31557 Score = 79.8 bits (188), Expect = 8e-13 Identities = 102/481 (21%), Positives = 195/481 (40%), Gaps = 35/481 (7%) Query: 1010 LVVKETIPEFI--RKLQDFEVKEKDVAI-LEVEINSETA-DVVWERDGEIIKPKKNKYDF 1065 LV +E +P+F +L+ V + +I + V I A +VVW ++ P K + Sbjct: 20403 LVDREEVPDFELDAELRKTLVVKSGASIRIFVPIKGRPAPEVVWYKENV---PLKGRAHI 20459 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQNQKVNKG 1121 + + I + +D G+Y L + ++ V VV+ P + + Sbjct: 20460 DTTESYTLVVIPECTRYDAGKYVLTLENVAGKKTGFVNVRVVDTPGPPVNLKPREITKHS 20519 Query: 1122 NKATFEIELTKGDALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 +EI L G + ++ + + E + +T + +K KI D L++A EY V Sbjct: 20520 ITLQWEIPLIDGGSKIKNYIIEKREATRKAYSVITTNWQKCSYKIPD--LEEAAEYYFRV 20577 Query: 1181 GNSKCTAI-LTVEEPSINFTLRLP----EFILVPANTD-AYLTVEIP--DETLDVTWYKK 1232 I E P + P + I+ + D A L P D +T Y Sbjct: 20578 SAENEMGIGEPAETPDPIRASQAPSAPDDLIVTDVSKDTATLAWTKPKHDGGSRITGYVI 20637 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT----------KLKVE 1282 ++ ++D++++ ++ +K I + E+ + + +++ + K + Sbjct: 20638 EAQLKDSDQWAHVTTIKALDYIATELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTT 20697 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 EF + + Y++ K G ++ + + P+P W + +K+ + + S Sbjct: 20698 APEFDLRSI-YQKTVVAKAGDNLKVEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASS 20756 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 L I +++ D G Y + +N G + V + D P PP P + E+ + I W Sbjct: 20757 TILNINEIKRKDGGQYSMTGKNILGTVTENITVQVHDIPGPPTGPIKLDEVSCDYVLISW 20816 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 + PEN G I Y+VE +E T W+ + + +T L T Y+FR A N Sbjct: 20817 EAPENDGGVPINNYIVEMRETTGTSWMELAATVIRTTFKAARLTTGIEYQFRVKAQNRYG 20876 Query: 1461 I 1461 + Sbjct: 20877 V 20877 Score = 77.4 bits (182), Expect = 4e-12 Identities = 37/96 (38%), Positives = 63/96 (65%), Gaps = 1/96 (1%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++ P F+++L+ GS V+ + +V G P P + ++R+ A I+ S DFQ+ D D + Sbjct: 100 ETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGD-L 158 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +L+I E FPED+GT++ A N++G A+ST EL+V+ Sbjct: 159 YSLLIAEAFPEDSGTYSVSASNSSGRATSTAELLVQ 194 Score = 77.4 bits (182), Expect = 4e-12 Identities = 74/313 (23%), Positives = 134/313 (42%), Gaps = 24/313 (7%) Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTW 1229 +D GE S V S +++P ++ ++ I+V A L + + VTW Sbjct: 17847 NDGGE-SAWVSTSDIVVKEEIQKPVLD--MKFVGTIVVKAGESVRLEAGLRGKPQPTVTW 17903 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFP 1287 K K+ D + ++ + ++ K D +Y + T V V++ P Sbjct: 17904 VKDKAT-GDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVTVLDIP 17962 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT- 1346 + R+ +I S V + P+ + V+S II+KC+ + + SASL Sbjct: 17963 GPV----RDMKISGISTDKCRVAWDP-PEDDGGCEVDSYIIEKCETRRMVWSTYSASLVT 18017 Query: 1347 ----IKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSI 1397 + ++ + I+++R EN G + I+ K P PP P + +I + Sbjct: 18018 NYCNVTRLVEGNEYIFRVRAENKMGTGPPMESRPIIAKTQYNRPGPPDAPEVTKIGKDEM 18077 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 + W PEN G +I Y++E +E W+ V I++ + + NL N Y+FR A Sbjct: 18078 TVVWAPPENDGGKSITGYILERKEKRAVRWVPVTKSPISERRMKVTNLIPNHDYQFRVKA 18137 Query: 1456 VNEVDISDASETT 1468 NEV + + S+ + Sbjct: 18138 ENEVGLGEPSKAS 18150 Score = 76.6 bits (180), Expect = 7e-12 Identities = 136/624 (21%), Positives = 243/624 (38%), Gaps = 94/624 (15%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + + V+ G + IP+P ++W + + E + H Sbjct: 3012 PPQIIRHMQPLSVEAGKPARFSVEVTGIPQPQVSWYKNSQALSSGFKCKFLREGNEHTLL 3071 Query: 693 SV-LKITNVKKFQ---EGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747 + + + ++ + Y V + +P V+ TG PP V+ P+++ Sbjct: 3072 LIEVFPEDAAQYNCEAKNDYGVATSSASLNVEVPEVVSPDTGAPLSPPVVLTPIQNTSAN 3131 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTL 805 +G+S +V G TITW +K +K + S D + + +DEG YT Sbjct: 3132 EGQSARFQCRVSGEDL-TITWYCKDKEIKQSDIFRVSQFDENCQLEITRVYPEDEGEYTC 3190 Query: 806 KAENSEGIAETSAVITVEEPTE-----------ENAEPPLFINRFQEITVKEKGTI---- 850 A NS G+ SA++ V+ TE + P I Q+ + +K + Sbjct: 3191 VARNSAGMVSCSALLKVDGETEVMDYSSKFPPQATSSPLTSIKTIQKDAIGQKPSFFQPI 3250 Query: 851 -----------KLVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDS 897 + A V+ P P I+W+ N + I P++ + +FD L+I + S Sbjct: 3251 MSSVVAHGEVARFHACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFS 3310 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957 E +G Y C A N G+++ A + + E+VT V+ ++ EE K +S TV Sbjct: 3311 E-HAGQYTCKAVNIRGEAACSANLAV-TEEVTRVREEIEAKIEEEVKEF-----SSLTVK 3363 Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP 1017 T+ ++E + + ++ + ++ + + S+ L K P Sbjct: 3364 TE----EEEETYSTSLHLPEKSK---------------TLELKPEQKRFSSSLERKREKP 3404 Query: 1018 EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 F KL EV + V ++ V W +G+ I + Y F + L I Sbjct: 3405 VFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAI-TSSSIYTFVEERDEYSLII 3463 Query: 1077 RNTSVHDEGEYSCILRD---ESCTAEVTVVEL-------------------PPEIITRLQ 1114 EGEYSC + ++ + VEL PP T++Q Sbjct: 3464 TKVKKDYEGEYSCTASNRFGQTTCKTILKVELSQLSAAEKWVEKMFKIPGQPPCFTTQIQ 3523 Query: 1115 NQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY-DCDLD 1171 + +G++ F+ ++T G V+WFK S+I+ S + + I + Sbjct: 3524 PVQCVEGSEVKFQYKVT-GTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLIMSNIQQR 3582 Query: 1172 DAGEYSCEV----GNSKCTAILTV 1191 D+G Y+C+ G + C+A L V Sbjct: 3583 DSGLYTCKAVNPFGEASCSAELIV 3606 Score = 73.7 bits (173), Expect = 5e-11 Identities = 78/346 (22%), Positives = 137/346 (39%), Gaps = 17/346 (4%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250 E P I+ L + + V A L I VTW K+ +++ + + + Sbjct: 18272 EHPEIDLDASLRKGLSVRAGCPIRLFATIRGRPAPKVTW--KRIGVDNVIRRGHVDQIDT 18329 Query: 1251 RT-LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 T L+I + + +D +Y+ L + + ++V+V++ P + + K + Sbjct: 18330 MTFLVIPESSREDSGKYSLTLSNPSGEKAVFVRVKVLDTPGPVGGLDATDITKTSCQLAW 18389 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 L P +IV + + + T + D K S I + +++ N G Sbjct: 18390 LPPENDGGSPILNYIVEKREVDRKTWTNCTNDLKKTSFKITNLTPGIEYYFRVMAVNKYG 18449 Query: 1368 HA---DVEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 D + D +P PP K ++LEI +S + W +P G S I Y+VEYQ+ Sbjct: 18450 IGLPQDSPKSYLATDPKSEPDPPKKMDVLEITKNSATLGWLKPLRDGGSKINGYIVEYQQ 18509 Query: 1422 IDTTE--WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 E W S + + LK N+ YRFR A N + S A E ++V KE + Sbjct: 18510 DGQPEDKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEGIFEV-KEQLM 18568 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + + +T + + + G P P W R + T+ Sbjct: 18569 APKIIVSDV--VTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTS 18612 Score = 69.7 bits (163), Expect = 8e-10 Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 6/198 (3%) Query: 1276 TTKLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKK 1330 TT+ V E+ P + + E + +K G + + P P W + K Sbjct: 19999 TTEPLVCKDEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKS 20058 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + S S++L+IK + G Y + N G D ++ V +LD P PPG Sbjct: 20059 SDIVQISSTPTSSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKVLDVPGPPGPIEAS 20118 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSY 1449 + + + W PE G +I Y++E +E W + +N+ + L + Y Sbjct: 20119 SVSAEKCTLTWLPPEEDGGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEY 20178 Query: 1450 RFRAYAVNEVDISDASET 1467 FR AVN+ D +++ Sbjct: 20179 IFRVSAVNQYGTGDVTQS 20196 Score = 67.7 bits (158), Expect = 3e-09 Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 4/122 (3%) Query: 485 QKKLNEKIDKLPVF----EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQ 540 +KK E+ KL + EK AP +E+++ + V+F C+V G P P+ Sbjct: 1822 EKKKEEEERKLTIPTIRPEKVALSPSMEAPKILERIQSQTVALADEVRFRCRVIGKPDPE 1881 Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 WF+ +++ S Y+ +D+V LVIR+V ED+ + A N AG ASS L+V Sbjct: 1882 CQWFKNGILLEKSDRVYWYWPEDHVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLV 1941 Query: 601 EA 602 +A Sbjct: 1942 QA 1943 Score = 66.5 bits (155), Expect = 8e-09 Identities = 32/91 (35%), Positives = 50/91 (54%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F +++P +GS V+F+ +V G P P + WF+ + IK SQ + + D L+ Sbjct: 3516 PCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLI 3575 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + D+G +TC A N G AS + ELIV Sbjct: 3576 MSNIQQRDSGLYTCKAVNPFGEASCSAELIV 3606 Score = 64.9 bits (151), Expect = 2e-08 Identities = 70/295 (23%), Positives = 115/295 (38%), Gaps = 24/295 (8%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250 E P I +L + A T L +I + V W K V++ ++ T+ + Sbjct: 13401 EPPEIQLDAKLLAGLTAKAGTKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGH 13460 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 TL I K DD Y +++ ++T + V +++ P ++ S++T Sbjct: 13461 STLSIAKTKRDDTATYIIEAVNSSGRATATVDVNILDKPGPPAAFDI-------SEITNE 13513 Query: 1309 VDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 A+ P D+ +IV K + K S K + K+ I+++ Sbjct: 13514 SCVLAWNPPRDDGGSKVTNYIVERKAVDSEIWYKLSSTVKQTTYKATKLVAFKEYIFRVY 13573 Query: 1362 LENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 EN G + I+ D P PP K +I ++ + W EP+ G S I Y Sbjct: 13574 AENQFGIGAPAEHAPIIARYPFDTPGPPYKLEPSDIAKDAVTLSWYEPDEDGGSPITGYW 13633 Query: 1417 VEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 VE E D +WI I T ++ L T Y+FR A N S+ T+ Sbjct: 13634 VERYEPDHDKWIRCNKLPIRDTNFRVKGLPTRKKYKFRVLAENLAGPGKPSKETD 13688 Score = 63.7 bits (148), Expect = 5e-08 Identities = 53/187 (28%), Positives = 85/187 (45%), Gaps = 13/187 (6%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKK---NKYDFEKRGHIR 1072 P F + LQ E A E +++ +V W RDG+++ + F G Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSD-GRAV 64 Query: 1073 KLYIRNTSVHDEGEYSCILRD----ESCTAE--VTVVELPPEIITRLQNQKVNKGNKATF 1126 + T+ H G +S + + TAE VT PP I RLQ+ V +G++ Sbjct: 65 LMIPAVTAAHS-GRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRL 123 Query: 1127 EIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 ++ +T A +V+++++G+EIQ S Q+ DG L I + +D+G YS NS Sbjct: 124 DVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSG 183 Query: 1186 TAILTVE 1192 A T E Sbjct: 184 RATSTAE 190 Score = 63.7 bits (148), Expect = 5e-08 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 3/120 (2%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT 1436 +D P PGKP + ++ +S + W +PE+ G + I Y+VE + T EW+ V NI Sbjct: 13696 IDPPWAPGKPTVKDVAKTSAFLQWTKPEHDGGAKIESYIVELLKSGTDEWVRVADNIPSL 13755 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + ++ L Y FR AVN S+ SE ++ V+ + ++ P+ + L +++ N Sbjct: 13756 EHFLKGLMEKQEYSFRVRAVNVAGESEPSEPSD--PVLCKERLNPPSPPRWLLVVSSSRN 13813 Score = 63.3 bits (147), Expect = 7e-08 Identities = 61/289 (21%), Positives = 110/289 (38%), Gaps = 11/289 (3%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVE--IPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 E P+I + + + V A +T + W K + ++ + S Sbjct: 20010 EPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAVWSKAGREFKSSDIVQISSTPT 20069 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 TL I+ + + EYT + K+KV+V++ P E +T Sbjct: 20070 SSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKVLDVPGPPGPIEASSVSAEKCTLTW 20129 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 L + +I+ + + TK + + K+ + I+++ N G Sbjct: 20130 LPPEEDGGCSIKSYILEKRETSRLLWTKLAENVMDCRYVASKLIKGNEYIFRVSAVNQYG 20189 Query: 1368 HADVEMN--VTILDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 DV + V ++D P PP KP I + +++ I W P G S I Y+VE +E Sbjct: 20190 TGDVTQSGPVKMVDSFGPPGPPSKPEIDNVSKNAVTISWKRPTVDGGSDIRGYIVERKER 20249 Query: 1423 DTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 W+ S K ++ + + L Y FR A N+ + SE ++ Sbjct: 20250 RGMRWVRASKKTVSDLRFKVSGLSEEIEYEFRVTAENKAGFGEPSEPSQ 20298 Score = 62.5 bits (145), Expect = 1e-07 Identities = 82/336 (24%), Positives = 139/336 (41%), Gaps = 51/336 (15%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP E ++ T G + CQ+ G P P+I W+R + S+ ++M D N + Sbjct: 30165 APCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHSLS 30224 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 V+ + ED G +TC A N AG ++ +L+++A H Sbjct: 30225 VMTDE-QEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFH--------------------- 30262 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESD 687 P F K K Y G+ + L + P P I W + + + P EN+ + ES Sbjct: 30263 -----PGFPLKEK-YYAGCGTSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESY 30316 Query: 688 MHMYCSVLKITNV-KKFQEGTYTVVAVNREGEASLPIVLKIKTGEK----EPPQVIEPL- 741 H L I NV +K G Y V N+ G ++ VL+++ +K E P V++ L Sbjct: 30317 TH-----LVIRNVQRKTNAGRYKVQLSNKFG--TVDTVLRVEIQDKPLLPEGPVVVDALL 30369 Query: 742 -KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE 800 S+I+ ++ N K + + + G T + P ++ Sbjct: 30370 KSSVIISWKPPKDDGGSMITNYIVEKREAKEGEQWHLVSSAVSGTTCRV----PNLIESS 30425 Query: 801 GVY-TLKAENSEGIAET---SAVITVEEPTEENAEP 832 G Y + A+N GI+E+ +V+ ++ P E+ P Sbjct: 30426 GYYFRVSAQNQYGISESLEIPSVVIIKSPFEKPGVP 30461 Score = 62.1 bits (144), Expect = 2e-07 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 1/92 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E L P G V +CQ+ G P +I+WF+ ++ S +M + +A L Sbjct: 7123 PFFIESLEPMEVTAGDAVCLKCQIGGTPEIKISWFKADGKVRSSPTCKMEF-FKGIACLK 7181 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + +V D G +TC A+N+ G A+S+ L V+ Sbjct: 7182 LAKVAKSDIGEYTCKAENSIGSATSSCHLTVQ 7213 Score = 61.7 bits (143), Expect = 2e-07 Identities = 47/174 (27%), Positives = 75/174 (43%), Gaps = 9/174 (5%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS--QDFQMYYDDDN 564 + AP F + L+ +GS FE QV G P P+++WFR ++ + Q+ + D Sbjct: 3 TQAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGR 62 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 A L+I V +G F+ A N AG A+ST EL+V A + + Sbjct: 63 -AVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQGSQV 121 Query: 625 XADI-LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 D+ + GIP P ++ EG++I + + D+ L E D Sbjct: 122 RLDVRVTGIP-----APVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPED 170 Score = 61.3 bits (142), Expect = 3e-07 Identities = 33/101 (32%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +Q + P F KL+ + GS Q EC V G +TWF++ I+ + + + +N Sbjct: 5734 DQIIKPSFTRKLKETESIKGSFTQLECLVSGSLPINVTWFKENKEIEADEKHKCIF-FEN 5792 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 A+L I + D+G +TC+AKN AG + L V+ P S Sbjct: 5793 AASLEISRLDSSDSGNYTCIAKNQAGSDQCSGTLKVKEPPS 5833 Score = 60.9 bits (141), Expect = 4e-07 Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T ++ P F +K+ +G VQFEC+V G +++W + ++ ++ M + Sbjct: 7211 TVQDVKTPPSFPKKITSIMQIEGQPVQFECRVAGSSPMEVSWLKDGEALRSDSEYTMSF- 7269 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 DDN A L I + +G +TCVA N+ G AS +L ++ P Sbjct: 7270 DDNSAVLNIAKGEMRHSGEYTCVATNSVGSASCRAKLTLQEP 7311 Score = 60.5 bits (140), Expect = 5e-07 Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 1/129 (0%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 L D+ YT K E K + P + E +M P+F L +G +V+F+ + Sbjct: 31387 LSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLR 31446 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 V G P P + W + ++ ++ +D + L IRE ED+GT+ A N AG A Sbjct: 31447 VSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVTATNTAGSA 31506 Query: 593 SSTTELIVE 601 S L VE Sbjct: 31507 SCQATLKVE 31515 Score = 58.4 bits (135), Expect = 2e-06 Identities = 48/198 (24%), Positives = 80/198 (40%), Gaps = 10/198 (5%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P + K G +L C+++ P P+I W G+E++ ++ + H Sbjct: 30163 GEAPCLKEDIKDTTTKLGESGILTCQIIGRPLPEIKWYRYGKELIQSRKYKMSSDGRNHS 30222 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-G 749 L + ++ EG YT AVN GE L ++ + P PLK G Sbjct: 30223 ----LSVMTDEQEDEGLYTCRAVNEAGEIETSGKLLLQAAPQFHPGF--PLKEKYYAGCG 30276 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK---DEGVYTLK 806 S+ L +G P P I W KP+ +T S T L + V+ + G Y ++ Sbjct: 30277 TSLRLHVVYIGRPIPQIMWFYGKKPLNPSENVIIENTESYTHLVIRNVQRKTNAGRYKVQ 30336 Query: 807 AENSEGIAETSAVITVEE 824 N G +T + +++ Sbjct: 30337 LSNKFGTVDTVLRVEIQD 30354 Score = 58.0 bits (134), Expect = 3e-06 Identities = 51/215 (23%), Positives = 83/215 (38%), Gaps = 9/215 (4%) Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 E S P++ K T + P + L+ M V+ + +VVG+P+P + W KN K + A Sbjct: 30545 EISEPVIPKSDTALRAP-FFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILA 30603 Query: 778 ----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 + + + ++ D Y ++A N G TS + VE P + P Sbjct: 30604 DGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAK--IYLP 30661 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893 L + + + + ++ P P +TW + EII+ + LV Sbjct: 30662 LHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVFL 30721 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 DSG Y A N G V +DV V Sbjct: 30722 KGVQRKDSGYYIICAKNRFGMDKQ--TVELDVADV 30754 Score = 57.6 bits (133), Expect = 4e-06 Identities = 45/148 (30%), Positives = 71/148 (47%), Gaps = 10/148 (6%) Query: 708 YTVVAVNREGEASLPIVLK---IKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPR 763 + V+A N G S P + E PQ+ E KS+ ++ GE++ LS + G P Sbjct: 27561 FRVIARNAVGTVSPPSQSSGYIMTKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPV 27620 Query: 764 PTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 P +TW K+ K V K L + S ++ G+YT++A+NS G + ++ V Sbjct: 27621 PQVTWYKDGKEVDKMLVDITTVIGSSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRV 27680 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTI 850 ++ T E PL RF I+ EK T+ Sbjct: 27681 QD-TPGPPEGPL---RFTNISA-EKATL 27703 Score = 57.2 bits (132), Expect = 5e-06 Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 7/135 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753 +TN+ + E + V+AVN +G++ P +L K+ P V L + V+ G + Sbjct: 22825 VTNLAQGGEYIFRVIAVNDKGKSD-PRLLASPVVAKDLAIEPTVRTKLSTYSVQVGYDLK 22883 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYTLKAENSE 811 + A++ G+P+PTITW K+ +K + DT H+ +K +D G+Y + N Sbjct: 22884 IEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDGGMYNIVVANVL 22943 Query: 812 GIAE-TSAVITVEEP 825 G E T +I +E+P Sbjct: 22944 GQQEATVEIIILEKP 22958 Score = 56.8 bits (131), Expect = 6e-06 Identities = 27/101 (26%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ + P+F KL+ + G +++ +C+ G I+WF I ++++ + + N Sbjct: 6839 DKIVPPLFSRKLKDTQSIVGKSMELDCKASGSAPLTISWFHNEVEIMSGPNYEITFTE-N 6897 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 TL + + D+GT+ C A N+AG A ++ L+V+ P S Sbjct: 6898 TCTLKVPTLKLSDSGTYKCKAVNSAGAAETSASLVVKEPPS 6938 Score = 56.4 bits (130), Expect = 8e-06 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 3/152 (1%) Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKP 774 +E E S + +K K +++ S+IV +G+S + G P PT+TW + Sbjct: 32118 KESETSAEVSVK-KIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRT 32176 Query: 775 VKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 V + T + L+ V+ DEG YT+ ENSEG E + + +P + Sbjct: 32177 VVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEEVT 32236 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 P + + IK +PVPS+ Sbjct: 32237 PTQVKSPEPSVASPVPPIKSPESSVTSPVPSV 32268 Score = 56.0 bits (129), Expect = 1e-05 Identities = 102/484 (21%), Positives = 193/484 (39%), Gaps = 44/484 (9%) Query: 154 EKSDLFDSQEDESKPDV--SQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV 211 EK+ D + KP + + P + +A + P E +P K + ++P K Sbjct: 10435 EKTKEIDVPVKKEKPSIPDKKEPDEVSVKAVTRPAKDEVPTEPKEKLVKGKGKIPSKDQE 10494 Query: 212 PDD---KETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXX 268 P+ K ++ P++ + + K +RK +E+S P D + Sbjct: 10495 PEKVQLKPFTKKPSAGSPKEKEAAEPKDRKPIELS-PLSRAPKDDIKKEPSIPTKKIDSQ 10553 Query: 269 XXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGS-------IKQNGILSRNIKEAA 321 ++ K ++ T+ PP+ + P+ + + G+L + +E Sbjct: 10554 ETPDKAKEVEKISTPVPVEDKTT-PPKKVTPVKKITPKEDEKKPIVIKKGVLPKEAEEKE 10612 Query: 322 KVK-------KQVFVPPKLPD--VEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELP 372 ++K K P K+P VEKT+ + + ++ + I K + E + Sbjct: 10613 EIKLKPVERTKSGIEPEKIPSPKVEKTKPAESVPVQRKPIDDLTKTPKTISPKDSTEAVI 10672 Query: 373 KEDVPEQYTITPRKSSAQKIDEIV--DEVTIKKRLNPFEIFYTPVEVRCGDTVFAV-YSY 429 + VP + I+P++ +++ +I D++ + K L+P + V + + VF + Y Sbjct: 10673 LKKVPHK--ISPKQEKSEETPQISGDDKIPVLKELSPGAVELRKVSTQFEEEVFEEEFEY 10730 Query: 430 VAETDEAINLVEGERLYILDT---SNQDWWYVQKHLTEEKGWVP---AQYLMDENNYTQY 483 AE ++ G L D+ + Y+++ E G A+ + Sbjct: 10731 EAEYEDEEEEAWGWELASRDSYGSEGSEEQYLEEGALETPGMPGGRRAKQTPSPGEGGKG 10790 Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPI-FVEKLRPKHTPD----GSTVQFECQVEGYPR 538 K DK P + P + P+ FV++L+ + GS+ FECQ+ P Sbjct: 10791 RGLKPGAGGDK-PPGDSPFGFQLKAVPLKFVKELKDIVLQEAESIGSSAVFECQIS--PS 10847 Query: 539 PQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 IT W + + ++ S + + D L I +V D G +TCVAK +ST + Sbjct: 10848 TAITTWMKDGSNLRESPKHK-FTSDGKDRKLQIIDVQLSDTGEYTCVAKLGNKEKTSTAK 10906 Query: 598 LIVE 601 LIVE Sbjct: 10907 LIVE 10910 Score = 55.6 bits (128), Expect = 1e-05 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 7/134 (5%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEKE--PPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764 + V AVN+ G+ K T +KE PP + +E ++VR GE+ I+ ++ G P P Sbjct: 16458 FRVSAVNQIGQGKPSFSTKPVTCKKEFEPPNLDLEFRDKLVVRVGETCIIQSRYTGKPEP 16517 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 TI W KN++ ++A + + + S+TI K K+ G Y + ENS G + + Sbjct: 16518 TIKWFKNDEELQANEEIALTTAKNRLSLTIEKAKR-DHSGKYMVVLENSIGTRKGICTVN 16576 Query: 822 VEEPTEENAEPPLF 835 V + + P +F Sbjct: 16577 VVDRPQPPEGPVIF 16590 Score = 55.6 bits (128), Expect = 1e-05 Identities = 49/204 (24%), Positives = 87/204 (42%), Gaps = 10/204 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + + V ++ ++V P+P + W G+EI+ D + ++ Y Sbjct: 30561 PFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILAD-GAKIKVQEFKGGYFQ 30619 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752 L I+N + Y + A N+ G S + L ++ K P ++ + ++ +GE V Sbjct: 30620 -LVISNADENDAAAYQIRATNQLGSISTSMNLDVEVPAKIYLPLHLQGMGAVHAIRGEVV 30678 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAEN 809 + + G P P +TW K + + T S T LK + KD G Y + A+N Sbjct: 30679 TIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVFLKGVQRKDSGYYIICAKN 30738 Query: 810 SEGIAETSAVITVEEPTEENAEPP 833 G+ + TVE + +PP Sbjct: 30739 RFGMDKQ----TVELDVADVPDPP 30758 Score = 55.2 bits (127), Expect = 2e-05 Identities = 24/79 (30%), Positives = 45/79 (56%), Gaps = 2/79 (2%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G T ++ C+V GYP P++ W+ +I+ S+ F+++Y D + L I + D+G Sbjct: 1626 EGETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRLHY--DGIHYLEITDCKSYDSGDVR 1683 Query: 583 CVAKNAAGFASSTTELIVE 601 +A+N G A T +L ++ Sbjct: 1684 VLAENPEGTAEHTVKLEIQ 1702 Score = 54.4 bits (125), Expect = 3e-05 Identities = 64/262 (24%), Positives = 101/262 (38%), Gaps = 32/262 (12%) Query: 1428 ISVKNITKTQTSIQNLKTNSSYRF-RAYAVNEVDISDASETTEYY---------KVIKET 1477 I VK+I + + K S R AYA E+ + EYY + I ++ Sbjct: 31258 IYVKDIEECDDGLYRCKVVSEDREDNAYA--ELFVETVRSFREYYLGRSLKKPRRRIDKS 31315 Query: 1478 KI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----E 1530 KI + P PL N + ED+ P+P VTW + G ++K Y + Sbjct: 31316 KILQRPPEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLKAGHRIKPDPKKYTFTSDK 31375 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----- 1585 Y +A N GE SC + P ++ + ++ K Sbjct: 31376 GLYQLMIHNVDLSDDAEYTVVANNKFGE--DSCKARLNVAPH-AVAEDTMRPMFKRLLAN 31432 Query: 1586 ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHS 1640 G + G P P + W KNG LE + + ++ ++ I+E S Sbjct: 31433 IDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDS 31492 Query: 1641 SKYTIEASNTAGTSSVEVTLKV 1662 Y + A+NTAG++S + TLKV Sbjct: 31493 GTYRVTATNTAGSASCQATLKV 31514 Score = 54.4 bits (125), Expect = 3e-05 Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 14/138 (10%) Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 KP + V EG C + P P + W+ +G +V I V+ Y S L+I+ Sbjct: 32142 KPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTT----QYKSTLEIS 32197 Query: 699 NVKKFQEGTYTVVAVNREGE----ASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQG 749 +V+ EG YTVV N EG+ +L I I E P QV P S+ ++ Sbjct: 32198 SVEYSDEGNYTVVVENSEGKQEARCTLAINKPILKEEVTPTQVKSPEPSVASPVPPIKSP 32257 Query: 750 ESVILS-AQVVGNPRPTI 766 ES + S V +P P++ Sbjct: 32258 ESSVTSPVPSVKSPEPSV 32275 Score = 53.6 bits (123), Expect = 6e-05 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 8/146 (5%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL---EGIPPTFSKKPKAQYVDE 647 F+ L++ A + H +V A++L E PP F ++ ++ V + Sbjct: 58 FSDGRAVLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQ 117 Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS + L+ R+ IP P + + +G EI + + + D++ L I GT Sbjct: 118 GSQVRLDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYS----LLIAEAFPEDSGT 173 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKE 733 Y+V A N G A+ L ++ GE+E Sbjct: 174 YSVSASNSSGRATSTAELLVQ-GEEE 198 Score = 53.2 bits (122), Expect = 8e-05 Identities = 56/243 (23%), Positives = 89/243 (36%), Gaps = 21/243 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561 +E+ P F +KL V FEC++ G P + W ++ + +M + Sbjct: 1469 KEKQQKPHFKKKLTSVRMKRFGPVHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI-N 1527 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------------DHG 608 + +L + D+G TC A N G ++ LIV+ S Sbjct: 1528 EFGYCSLDYEVAYSRDSGVITCRATNKFGADQTSATLIVKDEKSLVEDSQLPEGRKVQRM 1587 Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 EM D+ E P P+ V EG CR+ P P + W Sbjct: 1588 DEMERIAHEGGPSGVTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWY 1647 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 G I + + + +H L+IT+ K + G V+A N EG A + L+I+ Sbjct: 1648 LNGLLIRKSKRFRLHYDG-IH----YLEITDCKSYDSGDVRVLAENPEGTAEHTVKLEIQ 1702 Query: 729 TGE 731 E Sbjct: 1703 QKE 1705 Score = 53.2 bits (122), Expect = 8e-05 Identities = 59/243 (24%), Positives = 90/243 (37%), Gaps = 33/243 (13%) Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 KK +IDK + ++P P F L + G V+F + +P P +TW + Sbjct: 31306 KKPRRRIDKSKILQRP--------PEFTLPLFNRSAYIGEDVRFGVTITVHPEPSVTWLK 31357 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 IKP + D + L+I V D +T VA N G S L V AP Sbjct: 31358 AGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNV-AP-- 31414 Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665 A + + P F + EG + + R+ P P + Sbjct: 31415 -------------------HAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTL 31455 Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W G+ + + V ++ D+ + +L I GTY V A N G AS L Sbjct: 31456 KWEKNGKPLEFRPQVEV-VQEDVDYF--ILHIRETLIEDSGTYRVTATNTAGSASCQATL 31512 Query: 726 KIK 728 K++ Sbjct: 31513 KVE 31515 Score = 53.2 bits (122), Expect = 8e-05 Identities = 46/185 (24%), Positives = 82/185 (44%), Gaps = 16/185 (8%) Query: 1008 TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK------N 1061 T + + + E IR+ + E +V I +E S T + R + P++ + Sbjct: 31821 TYIELMRPVSELIRQPRARIPTEAEVEI--IERRSPTPERTRPRSPSPVSPERRSSRSSS 31878 Query: 1062 KYDFEKRGHIRKLY-IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 +++ R I Y R ++ E +Y + T + ++ P I R+++ +V Sbjct: 31879 RFERSARFDIMSRYEARKAALKSERKYQVV------TQQPFSLDHAPRITVRMRSHRVPC 31932 Query: 1121 GNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 G F + + +K DA ++WF +G +IQ S+ Q T L+I DC +D G Y Sbjct: 31933 GQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVLSLQINDCQAEDTGTYRAL 31992 Query: 1180 VGNSK 1184 NSK Sbjct: 31993 CTNSK 31997 Score = 52.8 bits (121), Expect = 1e-04 Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 26/231 (11%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + + QE V+A N +G++ + P++ K T E P + V+ GE Sbjct: 23907 VAGLSSGQEYLLRVLAYNEKGKSDPRPLASPVIAKDVTIE---PSFKLTFNTYSVQSGED 23963 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809 + + G P P I W K+ + +K + T + T+LK K+ +D G YT+ A N Sbjct: 23964 LKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTATSTVLKIKEANREDSGKYTITATN 24023 Query: 810 SEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 + G + E A+I +++P PP + E++ T +++ PV + Sbjct: 24024 NIGTVTEEVAIIILDKP-----GPPTGPVKIDEVS----ATYVVIS--WEPPVYTGGCQI 24072 Query: 869 NNEIISPSETITQNFDGENIELVITNVD-SEIDSG---DYKCVASNSAGKS 915 NN ++ +T T N+ + + T + S++ +G ++ A N GKS Sbjct: 24073 NNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSEYQFRVFAENRYGKS 24123 Score = 52.4 bits (120), Expect = 1e-04 Identities = 45/207 (21%), Positives = 87/207 (42%), Gaps = 13/207 (6%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533 Q+PT +PL+++ G P P+V+W+RDG+ L A + + R Sbjct: 4 QAPTFTQPLQSVVALEGSAATFEAQVSGNPVPEVSWFRDGQVLTAAALPGAQISFSDGRA 63 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC--VVGIQQKPVITISNEDIKQKHKVGDEWL 1591 + A N G+ ++ +V + P I + G + Sbjct: 64 VLMIPAVTAAHSGRFSVRATNGAGQATSTAELLVTAETAPPNFIQRLQSLTVRQ-GSQVR 122 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + + GIP P V +Y+ G ++++ ++ I + I E S Y++ ASN++ Sbjct: 123 LDVRVTGIPAPVVKFYREGAEIQSSADFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSS 182 Query: 1652 G--TSSVEVTLKVYDK--PSKPEGPVI 1674 G TS+ E+ ++ ++ P+K +I Sbjct: 183 GRATSTAELLVQGEEEAVPAKKSKTII 209 Score = 52.4 bits (120), Expect = 1e-04 Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 3/140 (2%) Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 EG + + E IA V P + + I V E T K RVT Sbjct: 1580 EGRKVQRMDEMERIAHEGGPSGVTGDDMSEKSKPEIVLLPEPIRVFEGETAKYRCRVTGY 1639 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P + WY N +I S+ ++DG + L IT+ S DSGD + +A N G + H Sbjct: 1640 PTPKVNWYLNGLLIRKSKRFRLHYDGIHY-LEITDCKS-YDSGDVRVLAENPEGTAEHTV 1697 Query: 920 RVTIDVEKVTFVKHLQKSYE 939 ++ I +K F L+++ E Sbjct: 1698 KLEIQ-QKEDFRTILRRAPE 1716 Score = 52.4 bits (120), Expect = 1e-04 Identities = 27/94 (28%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+ G+ ++ ECQV+ I W R + + D ++ +++ +A L Sbjct: 4803 PSFVKSFESTTVAVGNPLRLECQVDEDTGVSIIWMRDGKKLHTTMDCKLAFEE-KIACLD 4861 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I++ +D GT+TC A N AG +S ++ + V+ P Sbjct: 4862 IQKSKLKDTGTYTCTAANEAGSSSCSSSVTVQEP 4895 Score = 51.6 bits (118), Expect = 2e-04 Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 7/137 (5%) Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 +YA E D + ET +KE + PT+ LKN+T E + L C G P P Sbjct: 715 SYAGEEWD-TKVPETAAIPSAVKEPVVP-PTLIAGLKNVTVTEGESVTLECQISGHPTPA 772 Query: 1513 VTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 + W+R+ +++ + + TYE + + C A ++ G + TSC + ++ Sbjct: 773 IMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFTCTATSEAGTISTSCYLLVK 832 Query: 1569 QKPVITISNEDIKQKHK 1585 I S E+I + K Sbjct: 833 VSEEIE-SREEITIQEK 848 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 K T +E P+F +KL P G TV+ EC + G ++TW + I+ ++++ Sbjct: 7305 KLTLQEPRYPPVFDKKLVPVDVSVGDTVELECHMTGSMPIKVTWSKDHKDIRTGGNYKIS 7364 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +N L I + D+G ++C A N G S +TE+ V+ Sbjct: 7365 C-VENTPHLTILKADKADSGRYSCHASNDVGKDSCSTEVSVK 7405 Score = 51.2 bits (117), Expect = 3e-04 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Query: 698 TNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 T + + E + + AVN G + S P+V+K +T E K+++ + G+++ Sbjct: 20661 TELVENAEYVFRIFAVNSSGRSEPRESRPVVIKEQTTAPEFDLRSIYQKTVVAKAGDNLK 20720 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSE 811 + V+G PRP + W K ++ +K + +T S TIL ++ KD G Y++ +N Sbjct: 20721 VEIPVLGRPRPLVVWKKEDQELKQTQRINIENTASSTILNINEIKRKDGGQYSMTGKNIL 20780 Query: 812 GIAETSAVITVEE 824 G + + V + Sbjct: 20781 GTVTENITVQVHD 20793 Score = 50.8 bits (116), Expect = 4e-04 Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + ET+A+ + +E PP I + +TV E ++ L +++ +P P+I W+R + Sbjct: 725 VPETAAIPSA---VKEPVVPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYR 781 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 I S ++ L+I +E DSG + C A++ AG S + + V + Sbjct: 782 IENSIDFQITYEKSYARLMIREAFAE-DSGRFTCTATSEAGTISTSCYLLVKVSE 835 Score = 50.4 bits (115), Expect = 5e-04 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 17/163 (10%) Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV 1102 V W + G IKP KY F + +L I N + D+ EY+ + ++SC A + V Sbjct: 31353 VTWLKAGHRIKPDPKKYTFTSDKGLYQLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNV 31412 Query: 1103 V-------ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQL 1154 + P L N +G F++ ++ A ++W K+G ++F +++ Sbjct: 31413 APHAVAEDTMRPMFKRLLANIDCVEGQSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEV 31472 Query: 1155 T-IDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192 D L I + ++D+G Y + G++ C A L VE Sbjct: 31473 VQEDVDYFILHIRETLIEDSGTYRVTATNTAGSASCQATLKVE 31515 Score = 50.0 bits (114), Expect = 7e-04 Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGES 751 +T++ + E + V+A N G A +P V+K+ + P +E + + +VRQG Sbjct: 29727 LTHMPQGAEYKFRVMACNAGGAGEPAEIPGVVKVTEMLEYPDYELEKIYQEGYVVRQGGV 29786 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + LS + G P PT W K + + + + + ++K D G Y L EN Sbjct: 29787 IRLSVPIKGKPLPTCKWTKEGRDISHRAMIATSEERTELVIKEAHRDDTGTYDLVLENKC 29846 Query: 812 G-IAETSAVITVEEPTEENAEPPLFINRFQEITVK--------EKGTIKLVARVTRNPVP 862 G A V + P + E PL + Q +V+ + G+ V R VP Sbjct: 29847 GRKAVYIKVKVIGRP--DPPEGPLEFDDIQARSVRVSWRPPSDDGGSDIFGYIVERREVP 29904 Query: 863 SITWYRNNEIISPSETITQNFDGENIE 889 WY + + + + + EN+E Sbjct: 29905 KAAWYTVDSRVVDTSLVVKGLK-ENVE 29930 Score = 49.6 bits (113), Expect = 0.001 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 9/129 (6%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860 + KA N+ G +E S +TV +E A + F+ I V++ I++ A VT P Sbjct: 15137 FRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRKNEPIEMPAEVTGLP 15196 Query: 861 VPSITWYRNNEII-SPSETI---TQNFD--GENIELVITNVDSEIDSGDYKCVASNSAGK 914 +P I W +++ +I P+E + T+ D + +L I V + +D G Y ASN G Sbjct: 15197 MPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGV-TRLDKGTYTVTASNRLGT 15255 Query: 915 SSHGARVTI 923 SH V + Sbjct: 15256 LSHSVTVEV 15264 Score = 49.6 bits (113), Expect = 0.001 Identities = 35/107 (32%), Positives = 53/107 (49%), Gaps = 10/107 (9%) Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 V+V E +PI+ E PP+V +E ++V+ G +V L A+V G P P + Sbjct: 18943 VSVPSEESDVIPII-----AEHVPPRVEISLEMKNLIVVKAGANVCLEAEVYGKPMPKVV 18997 Query: 768 WCKNNKPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEG 812 W K+ P+K A K H +++ L K+ G YT+ AEN G Sbjct: 18998 WKKDGAPLKLAEGMKMTQKVHHLSLELFSVTRKESGEYTITAENPSG 19044 Score = 48.8 bits (111), Expect = 0.002 Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 +++ ++ P KL G ++ E ++ G+P+P ITW + + +K + + D Sbjct: 22858 AKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNV-ADT 22916 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + TL I++ ED G + V N G +T E+I+ Sbjct: 22917 AHHTTLTIKDATREDGGMYNIVVANVLGQQEATVEIII 22954 Score = 48.0 bits (109), Expect = 0.003 Identities = 41/214 (19%), Positives = 84/214 (39%), Gaps = 26/214 (12%) Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----E 1530 E K + P E L E + T G P+PKV W+ +GK + T+ + Y Sbjct: 3398 ERKREKPVFESKLTPAEVTIGESVRFTVTVSGFPKPKVQWFHNGKAI-TSSSIYTFVEER 3456 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV---- 1586 + Y C A N G+ ++ ++ ++ + + +++ K+ Sbjct: 3457 DEYSLIITKVKKDYEGEYSCTASNRFGQTTCKTILKVELSQ-LSAAEKWVEKMFKIPGQP 3515 Query: 1587 --------------GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIR 1631 G E + G P P+V W+K +++++ + ++ + + + Sbjct: 3516 PCFTTQIQPVQCVEGSEVKFQYKVTGTPFPDVQWFKGNSQIKSSQTCSVVCNPDGSGFLI 3575 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + +++ S YT +A N G +S L V+ K Sbjct: 3576 MSNIQQRDSGLYTCKAVNPFGEASCSAELIVFHK 3609 Score = 47.6 bits (108), Expect = 0.004 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 9/117 (7%) Query: 712 AVNREGEASLPIVLKIKTGEKEPPQV-IEP-LKSMI-VRQGESVILSAQ-VVGNPRPTIT 767 A++ E + P+V K E EPP + I+P +K + V+ G +++++A ++G P PT Sbjct: 19992 AISAPSETTEPLVCK---DEYEPPTITIDPEMKDGVTVKAGGTIVITASSILGKPPPTAV 20048 Query: 768 WCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 W K + K+ + S T S +K K+ G YT+ A N GI + + V Sbjct: 20049 WSKAGREFKSSDIVQISSTPTSSTLSIKYASRKNTGEYTITASNPFGIKDEKVKVKV 20105 Score = 47.6 bits (108), Expect = 0.004 Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 5/121 (4%) Query: 697 ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGES 751 ++N++ + + V A+N EG + + V+++ E+ P + E K+++V+ G S Sbjct: 20370 VSNLQSGGKYHFRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGAS 20429 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + + + G P P + W K N P+K +++++ ++ D G Y L EN Sbjct: 20430 IRIFVPIKGRPAPEVVWYKENVPLKGRAHIDTTESYTLVVIPECTRYDAGKYVLTLENVA 20489 Query: 812 G 812 G Sbjct: 20490 G 20490 Score = 47.6 bits (108), Expect = 0.004 Identities = 35/138 (25%), Positives = 58/138 (42%), Gaps = 6/138 (4%) Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 E ETS V ++ K T+S + + + H + GD I+G P P V W G + Sbjct: 32119 ESETSAEVSVK-KIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTV 32177 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 + +++T + S + I ++ S YT+ N+ G TL + +KP E Sbjct: 32178 VSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARCTLAI-NKPILKEEVT 32236 Query: 1674 IMREISRESVTIEWKPPL 1691 + S E PP+ Sbjct: 32237 PTQVKSPEPSVASPVPPI 32254 Score = 47.2 bits (107), Expect = 0.005 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 5/119 (4%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP--LKSMIVRQGESVILSAQVVGNPRPT 765 + V + N GE++ I E+ V++ + +++V+ GESV L A + G P+PT Sbjct: 17841 FRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGESVRLEAGLRGKPQPT 17900 Query: 766 ITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +TW K +K P S G +S +L K D G Y + A N G A +TV Sbjct: 17901 VTWVK-DKATGDNPRISIDTGHDYSKFLLTKTKRSDTGKYVVTATNPAGSFTAYANVTV 17958 Score = 47.2 bits (107), Expect = 0.005 Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 7/155 (4%) Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG-----EASLPIVLK 726 E+ + DE V I S + + ++++K Y V AVN G E P+ K Sbjct: 26839 EQRIADETEWVTISSKGEVRTTEFVVSHLKPGVYYYYRVSAVNCVGTGRSIEIVQPVQAK 26898 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786 E + I I + G V + + G P P +TW K +K + + +T Sbjct: 26899 DILEEADVDLDISMSTQYIAKAGRDVEIVIPLKGRPAPNVTWRKGDKNISGDARYAIRNT 26958 Query: 787 -HSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819 +S T++ PK +D+ G Y L+ EN G +T V Sbjct: 26959 EYSTTLIIPKVTRDDTGKYLLEIENGVGEPKTITV 26993 Score = 46.8 bits (106), Expect = 0.007 Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 15/143 (10%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ + I G P P ++W++ ++EN ++ IT ++ + + I+E S ++T Sbjct: 756 GESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARLMIREAFAEDSGRFTCT 815 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPL----DDGGLELTKY 1701 A++ AGT S L V + EI SRE +TI+ K + D+ E++ Sbjct: 816 ATSEAGTISTSCYLLV----------KVSEEIESREEITIQEKQTVVEAKDETMSEISSV 865 Query: 1702 AIEKHEPDNNRWIKVADVDRDVE 1724 +++ P ++K V + VE Sbjct: 866 SVDTGAPAAPFFVKKPVVQKLVE 888 Score = 46.8 bits (106), Expect = 0.007 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-T 1436 L+ PSPP ++ +S + W PE G S I Y+VE +++ W +V K Sbjct: 13796 LNPPSPPRWLLVVSSSRNSAELKWTAPERDGGSPITNYIVEKRDVRRKGWQAVDTTVKEL 13855 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 + ++ L S Y FR A N V S+ E Sbjct: 13856 KYTVTPLNEGSLYVFRVAAENAVGPSEFCE 13885 Score = 46.8 bits (106), Expect = 0.007 Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Query: 710 VVAVN--REGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 VVA+N EGE L + ++ + P I ++VR GE + + A V G P P+ Sbjct: 14846 VVAINCAGEGEPGLTDAVIVRNPAEVPVIELDISVRNGVVVRAGEMLRIPAHVTGRPPPS 14905 Query: 766 ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 + W K++ + K + S ++K K D G Y ++A N GI Sbjct: 14906 LKWTKDDGDLEKDRMEVEEAGQDSTVVIKTTKRSDHGKYQIQAANPSGI 14954 Score = 46.4 bits (105), Expect = 0.009 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNP 860 + + A NSEG+ E S V V E + P ++ + + VK +I++ + P Sbjct: 20381 FRVSALNSEGLGEPSEVEQVVELVDREEVPDFELDAELRKTLVVKSGASIRIFVPIKGRP 20440 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P + WY+ N + I E+ LV+ + D+G Y N AGK + Sbjct: 20441 APEVVWYKENVPLKGRAHIDTT---ESYTLVVIPECTRYDAGKYVLTLENVAGKKTGFVN 20497 Query: 921 VTI 923 V + Sbjct: 20498 VRV 20500 Score = 46.4 bits (105), Expect = 0.009 Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 11/147 (7%) Query: 697 ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEK-EPPQV---IEPLKSMIVRQGES 751 IT + + QE + A+N+ G +PI +K +K + P++ E K ++V G S Sbjct: 23617 ITKLTEHQEYKVRICALNKLGVGEPVPIQGSVKPVDKMDAPEIELDSELRKGIVVHAGGS 23676 Query: 752 VILSAQVVGNPRPTITWCKN--NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + ++ G P P I W K+ + P KA K TH +TI + D G YTL +N Sbjct: 23677 MRINIPFKGRPIPEINWTKDDGDLPDKAQIDKGPDFTH-LTINICDR-NDAGKYTLTLQN 23734 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFI 836 S G SA ++V+ A LF+ Sbjct: 23735 SAG--TKSAFVSVKVLDTPGAPQNLFV 23759 Score = 46.0 bits (104), Expect = 0.011 Identities = 63/270 (23%), Positives = 105/270 (38%), Gaps = 32/270 (11%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--IT 880 +E E P+F+ + E T + +V P+P W+ + + + T I Sbjct: 1219 DESQLERLYKPVFVQKPSSFRCSEGQTARFDLKVVGRPMPDTFWFHSGQQVVNDYTHKIV 1278 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE----KVTFVKHLQK 936 DG +V+ + DSG++ VA N AGK++ +T++ + + F++ L K Sbjct: 1279 VKEDGTQSMIVVPAMPQ--DSGEWTVVAQNRAGKTTVSMTLTVEAKENLVRPQFIEKL-K 1335 Query: 937 SYETEEGKTV-------------ILECQTSHTVST-KWYHNKKE-ISGMDHREIIQEGRX 981 + +EG V I+ + S +S K+ H K E G H +I Q Sbjct: 1336 NISVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKIEGAKGQAHFQIPQTSGS 1395 Query: 982 XXXXXXXXXXXDVG--VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 G +C V + T E +PE + K KDVA E+E Sbjct: 1396 DSAWYTATAINKAGRDTTRCRVNVEVEYT-----EPVPERRLIIPKGTYKAKDVAPPEIE 1450 Query: 1040 -INSETADVVWERDGEIIKPKKNKYDFEKR 1068 ++ WE K K+ K F+K+ Sbjct: 1451 PLHLRYGQEQWEEGDLYDKEKQQKPHFKKK 1480 Score = 46.0 bits (104), Expect = 0.011 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRN 859 + +K EN+ G++ + V +E PP+ + + I VK TI+L A + Sbjct: 17149 FRVKTENAIGLSRPDTTVPVL--CQEKLVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGL 17206 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHG 918 PVP+ W + E I SE T+ D +N V++ D + +G Y SNSAG + Sbjct: 17207 PVPTAKWVIDGEEIK-SEGNTK-IDTDNFSTVLSIADCTRNHTGIYILTVSNSAGSKTVS 17264 Query: 919 ARVTI 923 VT+ Sbjct: 17265 LNVTV 17269 Score = 46.0 bits (104), Expect = 0.011 Identities = 38/136 (27%), Positives = 66/136 (48%), Gaps = 12/136 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLK---SMIVRQG 749 ++ + + Q+ + V+A N G +S+P + K E +PPQ+ K +++V G Sbjct: 22136 VSGLVEEQQYEFRVIARNAAGVSSVPSDSTGAITAKD-EVDPPQIDLDAKYSQNVVVNAG 22194 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 ES + A ++G P P++ W K+ + + +T T L K+ D G YTL Sbjct: 22195 ESFRIDAGILGKPIPSVHWIKSGEELTNTARLEIKNTDFTTTLSVKEAIRVDGGQYTLLL 22254 Query: 808 ENSEGIAETSAVITVE 823 +N G E S +I V+ Sbjct: 22255 KNVGG--EKSVIINVK 22268 Score = 46.0 bits (104), Expect = 0.011 Identities = 89/439 (20%), Positives = 165/439 (37%), Gaps = 37/439 (8%) Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFI 836 T G T + K K E + + A N G+ ET+ + + +E+ E + L Sbjct: 22524 TPPSGITETRFEAKKLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEA-PDIDLDA 22582 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896 + + ITV+ G+++L + P P + W + I+ + I + LVI NV Sbjct: 22583 DLRKMITVRAGGSLRLFVPIRGRPTPEVKWGKTEGEINEAAQI--DITSSFTSLVIENV- 22639 Query: 897 SEIDSGDYKCVASNSAGKSSH--GARV--TIDVEKVTFVKHLQKSYETEEGKTVILE--C 950 + DSG Y N++G S RV T D+ VK + K+ T + +L+ Sbjct: 22640 NRFDSGKYTLTLENASGTKSAFISVRVLDTPDMPANFRVKEITKNSVTLTWEPPLLDGGA 22699 Query: 951 QTSHTVSTKWYHNKKEISGMD-------HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 + + K +K S + E ++EG +G+ Sbjct: 22700 KIKSYIVEKRESTRKVYSAVTTCNKMTWKIEPLEEGSIYFFRVLAENEHGIGL------P 22753 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 ET L + E +P+ K+ +V K V++ + + + + E+ ++K+ Sbjct: 22754 AETPEPLKISE-VPQPPGKVSVVDVTRKSVSLKWEKPEHDGGSRITYYEVEMQAKDQDKW 22812 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP---------PEIITRLQ 1114 + + N + E + I ++ ++ ++ P P + T+L Sbjct: 22813 SLCAQVKALDTVVTNLAQGGEYIFRVIAVNDKGKSDPRLLASPVVAKDLAIEPTVRTKLS 22872 Query: 1115 NQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 V G E ++ + W KDGS ++ + + + L I D +D Sbjct: 22873 TYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATREDG 22932 Query: 1174 GEYSCEVGNSKCTAILTVE 1192 G Y+ V N TVE Sbjct: 22933 GMYNIVVANVLGQQEATVE 22951 Score = 46.0 bits (104), Expect = 0.011 Identities = 69/350 (19%), Positives = 130/350 (37%), Gaps = 36/350 (10%) Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 ++ P+I R +R+ G + ++ Q+ P N +W N + I++ + + S Sbjct: 31915 LDHAPRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQFTNMSGVL 31974 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------------DKPSPPG-KPNIL 1390 SL I + D G Y+ N+ G A + + D+ +P P+I Sbjct: 31975 SLQINDCQAEDTGTYRALCTNSKGEASDYATLDVSGGAFTTYSSRRRDEEAPTQIVPDIT 32034 Query: 1391 EID---SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ---TSIQNLK 1444 + D S++I + + E E+ + E + + + S + L Sbjct: 32035 KTDYYHSTTIRASSASRTHLEIQEFKTKLTERHEVSSFEKYESQRLASSPIRYASTEYLS 32094 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEY-------YKVIKETKIQSPTVEKPLKNITTEPNE 1497 + S + +E +S S+ E K IK T + + + KP I +E + Sbjct: 32095 SASYSSSERHTTSEKHVSSESKLKESETSAEVSVKKIKAT-LSAKILTKPHSLIVSE-GD 32152 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAF 1553 C G P P VTW +G+ + ++ +T + + Y + Sbjct: 32153 SARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVE 32212 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 N G+ E C + I KP++ E++ E V + + I PE Sbjct: 32213 NSEGKQEARCTLAI-NKPIL---KEEVTPTQVKSPEPSVASPVPPIKSPE 32258 Score = 45.6 bits (103), Expect = 0.015 Identities = 24/91 (26%), Positives = 46/91 (50%), Gaps = 1/91 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F ++++ GS+ +FEC++E P WF+ ++ S+ ++ + ++L Sbjct: 4615 PVFRQRIQNLEVNVGSSAKFECEIEEAPGVTFKWFKSGTELRHSEKCRI-ISRHHTSSLE 4673 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I D+G +TC A N G S + +L V Sbjct: 4674 IFSPAVADSGEYTCKASNRHGSDSCSAKLTV 4704 Score = 45.6 bits (103), Expect = 0.015 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 LK + +F+ V GE + I +K +T E + ++V G + + Sbjct: 16153 LKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRI 16212 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAENSE 811 A V G P P I W N+ LP ++ +T SI+ ++K + +G+YTL A+N+ Sbjct: 16213 LAYVSGKPAPEIIW---NRDDAELPKEAAVETTSISSALVIKSCLRQHQGIYTLTAKNAG 16269 Query: 812 GIAETSAVITV 822 G + + ++ V Sbjct: 16270 GERKKAVIVEV 16280 Score = 45.6 bits (103), Expect = 0.015 Identities = 38/132 (28%), Positives = 62/132 (46%), Gaps = 10/132 (7%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIV---LKIKTGEKEPPQVIEPLK----SMIVRQG 749 +T++ + ++ + V+A N G S+P L E PP+ K ++ +R G Sbjct: 28635 VTSLVEGEQYEFRVIARNGAGVHSMPSASSGLITCKDEYTPPKAELDSKLVGETISIRAG 28694 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKA 807 ++L A V G P P + W K +K + S T ++ I+K D G Y L Sbjct: 28695 SDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYSLTYTSTRAMAIIKSCDRNDTGRYILTV 28754 Query: 808 ENSEGIAETSAV 819 +N+ GI +TSAV Sbjct: 28755 KNASGI-KTSAV 28765 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP ++R P G +F V+ P I WF I+ S +Q + + V +L Sbjct: 31918 APRITVRMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQESHKYQ-FTNMSGVLSL 31976 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I + ED GT+ + N+ G AS L V Sbjct: 31977 QINDCQAEDTGTYRALCTNSKGEASDYATLDV 32008 Score = 45.6 bits (103), Expect = 0.015 Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 5/98 (5%) Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL---ENDKEYNITTKEKT 1627 P I EDI + G V G P P + W + G KL E+ ++I T E Sbjct: 32662 PRIEALPEDISVE--TGKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTEDL 32719 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + + I +K + + YT++ SN G+ VT+ + K Sbjct: 32720 TTLIITGVKETDAGAYTLKLSNEHGSDLATVTISIRSK 32757 Score = 45.2 bits (102), Expect = 0.020 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 2/75 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860 + ++AEN+ G+++ S + + T+ P +F++ + + VK I+L A ++ P Sbjct: 14369 FRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVKRGEEIRLDANISGFP 14428 Query: 861 VPSITWYRNNEIISP 875 P ITW RNN I P Sbjct: 14429 YPQITWMRNNATIWP 14443 Score = 44.4 bits (100), Expect = 0.035 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 11/136 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV---IEPLKSMIVRQG 749 ++T + + Q Y V A+N+ G AS P + KEPP++ + L + + G Sbjct: 13362 EVTGLIEGQWYAYRVRALNKLG-ASKPCKSTDEILAVDPKEPPEIQLDAKLLAGLTAKAG 13420 Query: 750 ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + L A + G P P + W K + KP + + +++I K K+ D Y ++ Sbjct: 13421 TKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKR-DDTATYIIE 13479 Query: 807 AENSEGIAETSAVITV 822 A NS G A + + + Sbjct: 13480 AVNSSGRATATVDVNI 13495 Score = 44.4 bits (100), Expect = 0.035 Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 14/127 (11%) Query: 697 ITNVKKFQEGTYTVVAVNREG------EASLPIVLKIKTGEKEPPQVI--EPLKSMIV-R 747 +T + + Q + ++A N G E++ P+ +K + +PP++ + L+ ++V + Sbjct: 25381 VTGLIEDQRYDFRIIAKNAAGLFSEPSESTGPVTVK---DDVDPPRITIEDKLRQLVVIK 25437 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTL 805 GE + + A++ G P P I+W K+ K ++A T + T I++ +D G Y L Sbjct: 25438 AGEILRIDAEISGRPIPVISWAKDGKEIEAKARFEISSTLTSTTLIVRDAIRRDSGQYVL 25497 Query: 806 KAENSEG 812 +N G Sbjct: 25498 TLQNVAG 25504 Score = 44.0 bits (99), Expect = 0.046 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 12/126 (9%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P+ W+ +G ++ ND + I KE T + + S ++T+ A N AG + Sbjct: 1252 VVGRPMPDTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKT 1311 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-ELTKYAIEKHEPDNNRW 1713 +V +TL V K + P + ++ SV +G L EL AI PD W Sbjct: 1312 TVSMTLTVEAKENLVR-PQFIEKLKNISV--------KEGSLVELAVKAIGNPLPD-IVW 1361 Query: 1714 IKVADV 1719 +K +D+ Sbjct: 1362 LKNSDI 1367 Score = 44.0 bits (99), Expect = 0.046 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 14/147 (9%) Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS-----MIVRQ 748 ++ + N+ + + AVN GE+ I + + + E + LK + VR+ Sbjct: 15123 IMTVDNLDELHMYEFRAKAVNAFGESEPSITMTVVIQDDEVAPSLRMLKHFKGDLIRVRK 15182 Query: 749 GESVILSAQVVGNPRPTITWCKNN----KPVKAL--PTKSDGDTHSITILKPKKVK--DE 800 E + + A+V G P P I W K++ KP + L TK S T L V D+ Sbjct: 15183 NEPIEMPAEVTGLPMPKIEWLKDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVTRLDK 15242 Query: 801 GVYTLKAENSEGIAETSAVITV-EEPT 826 G YT+ A N G S + V + PT Sbjct: 15243 GTYTVTASNRLGTLSHSVTVEVLDRPT 15269 Score = 44.0 bits (99), Expect = 0.046 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 6/136 (4%) Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 V +V+ E P+ G E E L + + G +V L +V P+PTI W Sbjct: 26483 VGSVSNPSEIVGPVTCVDTYGAPEVDLPQEYLDVVKYKAGATVQLKIGIVAKPQPTIEWY 26542 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTE 827 K+ K +++ S +T T + ++ + G Y LK +NS G SA V + Sbjct: 26543 KDGKELESGAQISISNTTEFTCISVREATRLNTGTYELKIKNSLG----SAYAAVRVLVQ 26598 Query: 828 ENAEPPLFINRFQEIT 843 + PP +F++IT Sbjct: 26599 DKPGPPAGEIQFKKIT 26614 Score = 44.0 bits (99), Expect = 0.046 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V + +G P+P I W + I+K S+ + + +N A+L++R E+AG +T Sbjct: 27213 GQNVNIDLPYKGKPKPIIQWMKDDVILKESEQVR-FRQTENKASLIVRNARKENAGKYTL 27271 Query: 584 VAKN 587 V N Sbjct: 27272 VLDN 27275 Score = 43.6 bits (98), Expect = 0.061 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 1/75 (1%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 +PP +I L+N V +G T E +++ + WF++ I+ S Q+T + +L Sbjct: 740 VPPTLIAGLKNVTVTEGESVTLECQISGHPTPAIMWFREDYRIENSIDFQITYEKSYARL 799 Query: 1164 KIYDCDLDDAGEYSC 1178 I + +D+G ++C Sbjct: 800 MIREAFAEDSGRFTC 814 Score = 43.6 bits (98), Expect = 0.061 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEG 801 ++V+ G+ L A V G P P+I W K+ K ++ A D +S I K +D G Sbjct: 21107 VVVKAGDIFKLDAHVTGRPIPSIVWTKDGKELEDTAKMEIKTLDFYSCLINKDSLRRDGG 21166 Query: 802 VYTLKAENSEGIAE 815 YTL A N G A+ Sbjct: 21167 AYTLTASNPGGFAK 21180 Score = 43.2 bits (97), Expect = 0.081 Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 5/136 (3%) Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKG 848 T K + +Y + +++ E++ V T + +E + P+ +F I VK Sbjct: 17826 TFFMVDKCVENHIYQFRVQSTNDGGESAWVSTSDIVVKEEIQKPVLDMKFVGTIVVKAGE 17885 Query: 849 TIKLVARVTRNPVPSITWYRNNEI-ISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 +++L A + P P++TW ++ +P +I D L T D+G Y Sbjct: 17886 SVRLEAGLRGKPQPTVTWVKDKATGDNPRISIDTGHDYSKFLLTKT---KRSDTGKYVVT 17942 Query: 908 ASNSAGKSSHGARVTI 923 A+N AG + A VT+ Sbjct: 17943 ATNPAGSFTAYANVTV 17958 Score = 43.2 bits (97), Expect = 0.081 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 1/82 (1%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G + +F C ++G P P +TW + + S + +TL I V D G +T Sbjct: 32150 EGDSARFVCDIDGEPAPTVTWMHEGRTVVSSHRIHV-STTQYKSTLEISSVEYSDEGNYT 32208 Query: 583 CVAKNAAGFASSTTELIVEAPL 604 V +N+ G + L + P+ Sbjct: 32209 VVVENSEGKQEARCTLAINKPI 32230 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL--TIDGKKQ 1161 E PP+II +L+ + + F E + + + W+KD ++ S+H Q+ + DG Sbjct: 32447 EAPPKIIQQLKAEAFEDKIRMIFVAESSLREVV--WYKDSRKLSQSSHYQIHSSADGTCC 32504 Query: 1162 KLKIYDCDLDDAGEYSCEV 1180 L I D DD GEYSCE+ Sbjct: 32505 -LYISDVSEDDQGEYSCEI 32522 Score = 42.7 bits (96), Expect = 0.11 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 8/125 (6%) Query: 728 KTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785 K E EP +I E K+++V+ G S L G P P + W K + ++ + D Sbjct: 25813 KEREDEPVFLISNEMRKTLVVKDGSSFTLRVPFKGKPVPHVMWNKPDVDLRVRASIDTTD 25872 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 T + ++ D G YT+ +N G +A +T+ ++ PP I +E+T K Sbjct: 25873 TCTSVTIEQATRDDSGKYTVTLQNVAG----TATLTLSVKVLDSPGPPAHI-EVKEVT-K 25926 Query: 846 EKGTI 850 TI Sbjct: 25927 SSATI 25931 Score = 42.7 bits (96), Expect = 0.11 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 5/121 (4%) Query: 697 ITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPPQVIEP---LKSMIVRQGES 751 +T + ++ ++ V AVN GE S + + E P + P K++ +R G + Sbjct: 29036 VTGLASNKKYSFRVAAVNAMGTGEFSEGSMETAPSERVEIPDIELPDELKKTVCIRAGNT 29095 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L+ V G P P ITW K +++ + + I++ D G YT++AEN Sbjct: 29096 LRLNVTVSGRPAPVITWRKTGIDLQSRGFIDTTENSTSLIVEKVHRYDAGKYTIEAENPS 29155 Query: 812 G 812 G Sbjct: 29156 G 29156 Score = 42.7 bits (96), Expect = 0.11 Identities = 60/350 (17%), Positives = 138/350 (39%), Gaps = 38/350 (10%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 ++ K K P+ K + + P +++L+ + D + F + ++ W++ + Sbjct: 32428 MSPKRMKSPLTVKSPTPSKEAPPKIIQQLKAEAFEDKIRMIFVAESS---LREVVWYKDS 32484 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + S +Q++ D L I +V +D G ++C + G S T+ V Sbjct: 32485 RKLSQSSHYQIHSSADGTCCLYISDVSEDDQGEYSCEIISEGGAVSRTSFSFVGQVFQAI 32544 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667 +++T + + + S K + GS+++++ A+ ++ Sbjct: 32545 YTKVTAFVAAH-----------KAVQESVSSK-----IQGGSEMVIKRESAAVSSMHESF 32588 Query: 668 LFKG---EEIVPDENISVAIESDMHM----YCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 K E + + + S + ++M S+ +T+ + + ++++ + E + Sbjct: 32589 TSKSIHMESTMQEASFSSSAMAEMKFETMSMSSMSSMTSESVYAMSSSSIMSSHSHAEET 32648 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780 + + + + P++ + + V G+ + ++ G P P I W + K LP Sbjct: 32649 -SVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGG---KKLPG 32704 Query: 781 KSDGD------THSIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + D T +T I+ K D G YTLK N G + I++ Sbjct: 32705 EEDSSRFHIETTEDLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISI 32754 Score = 42.3 bits (95), Expect = 0.14 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 10/116 (8%) Query: 1571 PVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 PV S EDIK ++H L+ ++ +V W NG +++ KE+ + + T Sbjct: 4522 PVFENSLEDIKTEEHSEAKFSLIIRYVK-----KVNWLFNGKCIKSGKEFKCSKEHDTYT 4576 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 + I ++ + H +YT EA AG +S L V P P PV + I V + Sbjct: 4577 LVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTVI--PRVP--PVFRQRIQNLEVNV 4628 Score = 42.3 bits (95), Expect = 0.14 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 12/142 (8%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEK-EPPQVIEPL---KSMIVR 747 + K+ N++ + V AVN GE+ V + ++ ++ EPP++ L + + Sbjct: 16841 TTFKVINLEDGALYRFRVKAVNAAGESEPAYVPEPVRAQDRFEPPELQLDLGMPRELKAM 16900 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI---LKPKKVKDEGVYT 804 G + + A + G P P +TW KN V PT+++ +T T ++ D G YT Sbjct: 16901 AGTHINIMAGIKGMPFPKVTWKKNEADV---PTRAEIETSGTTTKLEMRYCNRTDCGDYT 16957 Query: 805 LKAENSEGI-AETSAVITVEEP 825 L EN G T V+ +++P Sbjct: 16958 LTVENPAGSKIATCTVLVLDKP 16979 Score = 42.3 bits (95), Expect = 0.14 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLF--INRFQEI-TVKEKGTIKLVARVTRNPVPS 863 A N G + T ++ EPP + + + +I TV T L A V P+P+ Sbjct: 23232 ARNGAGSVSRPSESTGSVTAKDEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPA 23291 Query: 864 ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W++ + E+ + + +N D + + LV+ + ID G Y SN AG S V Sbjct: 23292 MQWFKGDVEVENSARAEIKNTDFKAV-LVVKDA-IRIDGGQYTLHLSNVAGSKSVSFNVR 23349 Query: 923 I 923 + Sbjct: 23350 V 23350 Score = 42.3 bits (95), Expect = 0.14 Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 37/280 (13%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P+F V G D+ +E P P I W+ G+ + ++V+ + Sbjct: 23945 IEPSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQALKETTRLNVSSTAT---- 24000 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +VLKI + G YT+ A N G + + I++ K G P I+ + + V Sbjct: 24001 STVLKIKEANREDSGKYTITATNNIGTVTEEVAIIILDKPGPPTGPVKIDEVSATYV--- 24057 Query: 750 ESVILSAQVVGNPRPTIT-WCKNNKPV--KALPTKSDGDTHSITI----LKPKKVKDEGV 802 V+ P T C+ N V K T ++ T S TI +K K+K Sbjct: 24058 --------VISWEPPVYTGGCQINNYVVEKRDTTTTNWQTVSATIARTTIKISKLKTGSE 24109 Query: 803 YTLK--AENSEGIAET--SAVITVEEPTEENAEPPL-FINRF--QEITVKEK------GT 849 Y + AEN G + + S + V P E A P F++ +T++ K G+ Sbjct: 24110 YQFRVFAENRYGKSGSIDSTPVVVSYPFTEPAAPGAPFVSSVTKDHMTIEWKPPSNNGGS 24169 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 + + R SI W + N+++ + N E IE Sbjct: 24170 PIIGYHLERKEKNSILWTKLNKLLITDTRLRTNGLEEGIE 24209 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559 P S+ AP F ++LR + F +V G+P+P + W++ I+ ++ Sbjct: 30552 PKSDTALRAPFFKDELRDMCVKYKANATFVTKVVGHPKPVVKWYKNGKEILADGAKIKVQ 30611 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 LVI DA + A N G S++ L VE P Sbjct: 30612 EFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMNLDVEVP 30655 Score = 41.9 bits (94), Expect = 0.19 Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 A + GIP PE+ W+ N ++ K Y+ T+ + I + H+ +YT +A N Sbjct: 3265 ACVSGIPKPEISWFHNQQPIKPTKNVVYHFDEMTNTATLIIVDTFSEHAGQYTCKAVNIR 3324 Query: 1652 GTSSVEVTLKVYDKPSK 1668 G ++ L V ++ ++ Sbjct: 3325 GEAACSANLAVTEEVTR 3341 Score = 41.9 bits (94), Expect = 0.19 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 5/130 (3%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHT---PDGSTVQFE 530 L++ Y+ + K +NE + P +++Q + P K P + +G+TV+ Sbjct: 19616 LVEGKEYS-FRVKAINESAEGPPTELTILAKDQIVPPNCDLKGLPDSSYVAKEGTTVRLN 19674 Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 + G P P + W + + S + N L+IR+ DAG FT + +N+AG Sbjct: 19675 IPITGIPAPAVIWKKGDVTLSDSGRISVESTTTNTV-LLIRDCHRGDAGKFTIILRNSAG 19733 Query: 591 FASSTTELIV 600 + ++ V Sbjct: 19734 TKEAAIDIKV 19743 Score = 41.9 bits (94), Expect = 0.19 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+T++ V G P P ITW R+T I S+ F +N +L++ +V DAG +T Sbjct: 29093 GNTLRLNVTVSGRPAPVITW-RKTGIDLQSRGF--IDTTENSTSLIVEKVHRYDAGKYTI 29149 Query: 584 VAKNAAG 590 A+N +G Sbjct: 29150 EAENPSG 29156 Score = 41.9 bits (94), Expect = 0.19 Identities = 24/116 (20%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 T S + ++ ++ +K T + +S+ ++ + S Y + ++ + +E Sbjct: 32589 TSKSIHMESTMQEASFSSSAMAEMKFETMSMSSMSSMTSESVYAMSSSSI--MSSHSHAE 32646 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 T + + +P +E ++I+ E + + + C F G P P + W R GKKL Sbjct: 32647 ETSVRAALHSAQGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEWSRGGKKL 32702 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV K G +F+C + G + W + I D D N L Sbjct: 4710 PEFVSKPDSMTLFVGKQAKFQCVISGSEPMNVVWHKDNIAIS-LDDHYKESSDKNRYFLE 4768 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 I + D GT+ C A N+ G A+ TEL +V+ P Sbjct: 4769 ILNLQHSDQGTYLCKASNSVGTATCCTELRVVDKP 4803 Score = 41.5 bits (93), Expect = 0.25 Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 8/144 (5%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKS-MIVR 747 +V +T+ K++Q + V A N G + S P++ ++ + L+S + V+ Sbjct: 14357 TVKGLTHEKQYQ---FRVRAENAAGVSDPSRSTPLIKATDATDRPKVFLSGSLQSGLAVK 14413 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +GE + L A + G P P ITW +NN + P K + + ++ K+EG +A Sbjct: 14414 RGEEIRLDANISGFPYPQITWMRNNATIWPEPLKKRPERPIKKKKEKEEKKEEGAEKKEA 14473 Query: 808 ENSEGIAETSAVITVEEPTEENAE 831 + + + A +E EE E Sbjct: 14474 DAEKKEEDKEAKEEDKEKKEEKKE 14497 Score = 41.5 bits (93), Expect = 0.25 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 3/123 (2%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 +F+ T + ++R + ++P++ + K ++ ++ +IV+ G ++ L A + G Sbjct: 17148 RFRVKTENAIGLSRP-DTTVPVLCQEKLVPPIVEVDVKLIEGIIVKAGSTIRLPALMRGL 17206 Query: 762 PRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819 P PT W + + +K+ TK D D S + ++ G+Y L NS G S Sbjct: 17207 PVPTAKWVIDGEEIKSEGNTKIDTDNFSTVLSIADCTRNHTGIYILTVSNSAGSKTVSLN 17266 Query: 820 ITV 822 +TV Sbjct: 17267 VTV 17269 Score = 41.5 bits (93), Expect = 0.25 Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 6/114 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I PT K V G D+ +E R+ P+P I W G + ++VA ++ H Sbjct: 22863 IEPTVRTKLSTYSVQVGYDLKIEARISGHPKPTITWNKDGSALKQTTRVNVA-DTAHH-- 22919 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKS 743 + L I + + G Y +V N G EA++ I++ K G P I+ + + Sbjct: 22920 -TTLTIKDATREDGGMYNIVVANVLGQQEATVEIIILEKPGPPTGPVRIDEVSA 22972 Score = 41.5 bits (93), Expect = 0.25 Identities = 32/144 (22%), Positives = 64/144 (44%), Gaps = 6/144 (4%) Query: 784 GDTHSITILKPKKVKD-EGVYTLKAENSEGIAETS---AVITVEEPTEENAEPPLFINRF 839 G T S+ ++ V++ E + +KA+N GI++ A + ++EP E I++ Sbjct: 28228 GQTKSLKMVLEGLVENTEYEFRVKAQNDAGISQPRDALASVIIKEPRIEPTADLSSIDK- 28286 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 Q IT K + + ++ P P +TW + ++ ++ + L++ + Sbjct: 28287 QLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDRTTLLVKDA-KRG 28345 Query: 900 DSGDYKCVASNSAGKSSHGARVTI 923 DSG Y N+AG + V + Sbjct: 28346 DSGKYYLTLENAAGSKTFTVTVIV 28369 Score = 41.5 bits (93), Expect = 0.25 Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 1/100 (1%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +G+ P P+ V+ G + + C P P I W +G + +P E S + Sbjct: 32658 QGLAPRIEALPEDISVETGKVLTVACAFSGEPAPHIEW-SRGGKKLPGEEDSSRFHIETT 32716 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 + L IT VK+ G YT+ N G + + I++ Sbjct: 32717 EDLTTLIITGVKETDAGAYTLKLSNEHGSDLATVTISIRS 32756 Score = 41.1 bits (92), Expect = 0.33 Identities = 39/161 (24%), Positives = 63/161 (39%), Gaps = 9/161 (5%) Query: 1226 DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK--LK 1280 D W+ + V+ D ++ + +++I+ D E+T V + K+T L Sbjct: 1259 DTFWFHSGQQVVNDYTHKIVVKEDGTQSMIVVPAMPQDSGEWTVVAQNRAGKTTVSMTLT 1318 Query: 1281 VEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK--KCKHTKP 1336 VE E P+ ++ + +K GS V L V P P+ W+ NS II K H K Sbjct: 1319 VEAKENLVRPQFIEKLKNISVKEGSLVELAVKAIGNPLPDIVWLKNSDIISPHKYPHIKI 1378 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 A I + +D+ Y N G V + Sbjct: 1379 EGAKGQAHFQIPQTSGSDSAWYTATAINKAGRDTTRCRVNV 1419 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E++ P+F L T + S +F + Y + ++ W IK ++F+ + D Sbjct: 4516 EDKEGYPVFENSLEDIKTEEHSEAKFSLIIR-YVK-KVNWLFNGKCIKSGKEFKCSKEHD 4573 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 TLVI +V + G +TC A AG S+++ L V Sbjct: 4574 TY-TLVITKVMKDHEGEYTCEAVGEAGKTSTSSHLTV 4609 Score = 41.1 bits (92), Expect = 0.33 Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 15/145 (10%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGE-KEPPQVIEPLKS---MIVR 747 +V I N+ + ++ + ++AVN GE+ P +++ + K P++ + + + VR Sbjct: 15537 TVFTIPNLPELKKYRFRIIAVNEIGESEPSPRTSEVRIEDIKTAPKIFMDISADELLCVR 15596 Query: 748 QGESVILSAQVVGNPRPTITW-----CKNNKP--VKALPTKS---DGDTHSITILKPKKV 797 G + A + G P P +TW K K + LP S DT S+ + Sbjct: 15597 AGTPFKIPATITGRPAPKVTWEFDGKAKTEKKDRLHILPVDSQVESTDTTSVVTVPVSLR 15656 Query: 798 KDEGVYTLKAENSEGIAETSAVITV 822 G YT+ A+N G + + V Sbjct: 15657 SHSGRYTITAKNKSGQKHVNVRVNV 15681 Score = 41.1 bits (92), Expect = 0.33 Identities = 23/91 (25%), Positives = 40/91 (43%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ ++ + H G V + + G P P +TW + II + Q+ + + Sbjct: 30661 PLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQVIITRSFTSLVF 30720 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ++ V +D+G + AKN G T EL V Sbjct: 30721 LKGVQRKDSGYYIICAKNRFGMDKQTVELDV 30751 Score = 41.1 bits (92), Expect = 0.33 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 5/114 (4%) Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 +ETSA ++V++ + + + + V E + + V + P P++TW + Sbjct: 32120 SETSAEVSVKKIKATLSAK--ILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRTV 32177 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 S I + L I++V+ D G+Y V NS GK AR T+ + K Sbjct: 32178 VSSHRIHVSTTQYKSTLEISSVEYS-DEGNYTVVVENSEGKQE--ARCTLAINK 32228 Score = 40.7 bits (91), Expect = 0.43 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 831 EPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 EPP F++ V G T + +R T P P+I W++N+E + +E I + Sbjct: 16485 EPPNLDLEFRDKLVVRVGETCIIQSRYTGKPEPTIKWFKNDEELQANEEIALTTAKNRLS 16544 Query: 890 LVITNVDSEIDSGDYKCVASNSAG 913 L I + SG Y V NS G Sbjct: 16545 LTIEKAKRD-HSGKYMVVLENSIG 16567 Score = 40.7 bits (91), Expect = 0.43 Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 10/158 (6%) Query: 785 DTHSITILKPKKVKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPP---LFINRF 839 D+ T K ++D +Y +KA N+ G +E A + ++ EPP L + Sbjct: 16836 DSCPSTTFKVINLEDGALYRFRVKAVNAAGESEP-AYVPEPVRAQDRFEPPELQLDLGMP 16894 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 +E+ I ++A + P P +TW +N + I + +E+ N Sbjct: 16895 RELKAMAGTHINIMAGIKGMPFPKVTWKKNEADVPTRAEIETSGTTTKLEMRYCN---RT 16951 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 D GDY N AG V + ++K V+HL+ S Sbjct: 16952 DCGDYTLTVENPAGSKIATCTVLV-LDKPGPVQHLRVS 16988 Score = 40.7 bits (91), Expect = 0.43 Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 5/122 (4%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASL---PIVLKIKTGEKEPPQVIEP--LKSMIVRQGE 750 ++T ++ +E + V AVN G+ P +++ P I+ ++ IV+ G Sbjct: 27946 RVTELESGEEYKFRVCAVNGAGKGEFSETPHIVQAVDRLTSPEIDIDADFKQTHIVKNGG 28005 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 +V L G P P TW K + + + + DT S ++ D G YTL EN+ Sbjct: 28006 TVKLHIPFRGKPVPLATWTKADGDLGVMVDINTTDTFSTLTIENCTRYDAGKYTLSLENN 28065 Query: 811 EG 812 G Sbjct: 28066 SG 28067 Score = 40.3 bits (90), Expect = 0.57 Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV +P G+TV F V+G ++ WFR + I + ++ D A L Sbjct: 6937 PSFVTTPQPVEALPGTTVTFTATVQGSTPMKLKWFRGSKEIVSGRSCEIALRGD-TAILE 6995 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + + AG +TC N AG + L V+ Sbjct: 6996 LHNIDKSHAGEYTCQIINDAGKENCPVNLFVK 7027 Score = 40.3 bits (90), Expect = 0.57 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 7/131 (5%) Query: 797 VKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKL 852 +K+ G+Y ++A N+ G+ E V V E + P + ++ ++I V G I++ Sbjct: 16153 LKELGLYRFRVRAVNAAGVGEPGEVADVIEVKDRTIPPEVDLDATVKEKIVVHAGGVIRI 16212 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 +A V+ P P I W R++ + P E + + LVI + + G Y A N+ Sbjct: 16213 LAYVSGKPAPEIIWNRDDAEL-PKEAAVET-TSISSALVIKSCLRQ-HQGIYTLTAKNAG 16269 Query: 913 GKSSHGARVTI 923 G+ V + Sbjct: 16270 GERKKAVIVEV 16280 Score = 39.9 bits (89), Expect = 0.75 Identities = 32/136 (23%), Positives = 58/136 (42%), Gaps = 6/136 (4%) Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 D+ S ++ D+ + + LK +F+ + + EA + ++K P Sbjct: 18515 DKWTSYSVVKDLTIVVAGLKENTKYRFRVAARNAIGCSLAREAEG--IFEVKEQLMAPKI 18572 Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796 ++ + + R G +I+ A V G P P W + + + T + ++L K Sbjct: 18573 IVSDV--VTARAGSKLIVDALVSGKPAPVTKWKRGSDDIVTSDRVVIQKTPTTSLLMVKD 18630 Query: 797 V--KDEGVYTLKAENS 810 V KD G Y+L AENS Sbjct: 18631 VTRKDSGYYSLSAENS 18646 Score = 39.9 bits (89), Expect = 0.75 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 5/99 (5%) Query: 1091 LRDESCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSE 1145 L++ +AEV+V + L +I+T+ + V++G+ A F ++ A V W +G Sbjct: 32117 LKESETSAEVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDGEPAPTVTWMHEGRT 32176 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 + S+ I ++ K L+I + D G Y+ V NS+ Sbjct: 32177 VVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSE 32215 Score = 39.5 bits (88), Expect = 0.99 Identities = 15/50 (30%), Positives = 26/50 (52%) Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 + E + + + P+K+ + C GG P PK+ WY+DGK++K Sbjct: 1067 VAEHEAVASSFSTPVKSYRILEGMGVTFHCKMGGKPLPKIAWYKDGKRIK 1116 Score = 39.5 bits (88), Expect = 0.99 Identities = 34/181 (18%), Positives = 74/181 (40%), Gaps = 11/181 (6%) Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529 KV +++P + + +++ T +++ C G P P+ W+++G L+ + Y Sbjct: 1841 KVALSPSMEAPKILERIQSQTVALADEVRFRCRVIGKPDPECQWFKNGILLEKSDRVYWY 1900 Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN--EDIKQKH 1584 ++ A N GE + + +Q K V++ + ED K Sbjct: 1901 WPEDHVCELVIRDVLAEDSASIMVKAINIAGEASSHAFLLVQAKQVVSFTQTLEDAYAKE 1960 Query: 1585 KVGDEWLVTAVIEGIPP-PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 K + +VT E P +V W KN ++ + +Y + + K + + + ++Y Sbjct: 1961 K---DTMVTFECETNEPFVKVKWMKNNAEIFSGDKYRMHSDRKVHFLSVLIINMQDDAEY 2017 Query: 1644 T 1644 + Sbjct: 2018 S 2018 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 1/97 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 EQ + P F++ L G VQ C++ G + W + + ++ D+++ Sbjct: 6297 EQIIPPSFIKPLMEMEEIIGKNVQIGCKISGSLPITVEWEKDGTKLSGRTKHKILQDENS 6356 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 V+ L I + D GT+TC N AG + L V+ Sbjct: 6357 VS-LDIECLEKADTGTYTCKLANKAGSCECSGTLRVK 6392 Score = 39.1 bits (87), Expect = 1.3 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 2/100 (2%) Query: 504 EEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 +E+ + P F +K +G V+ E +V G + W++ I S + + + Sbjct: 7405 KERKIPPSFTKKPSTTIEDIEGKVVKIEGRVAGSQPLTVNWYKDGREIFTSDFYDVTFKS 7464 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 ++A L I++ D+GT+ C A N AG AS + + A Sbjct: 7465 -SLAVLCIKKSQLSDSGTYVCKATNEAGTASFEVSVHITA 7503 Score = 39.1 bits (87), Expect = 1.3 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 12/137 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQVIEPLKSMIVRQGESVIL 754 I ++K+ E + V AVN G AS P V I ++ I+ +++ +G V + Sbjct: 15851 IEDLKEGGEYEFRVKAVNEAG-ASRPSVTAGPIVIKDQTCAPSIDLREALEGAEGFDVNI 15909 Query: 755 SAQVVGNPRPTITWCK--NNKPVKALPTKSD-------GDTHSITILKPKKVKDEGVYTL 805 A++ G P P++ W K +KP +P + D D ++ K D +YTL Sbjct: 15910 VARIQGCPFPSLVWHKAPQDKPDDKVPVQYDKHVNKLVSDEKCSLFIQQSKRDDSAMYTL 15969 Query: 806 KAENSEGIAETSAVITV 822 A NS G A S +++ Sbjct: 15970 TATNSLGTATKSIKLSI 15986 Score = 39.1 bits (87), Expect = 1.3 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS + + V G P P++ W + + P + + + Y A +I+ D G + Sbjct: 28694 GSDLVLDAAVGGKPEPKVFWAKGDKELDPGEKYSLTYTSTR-AMAIIKSCDRNDTGRYIL 28752 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 KNA+G +S + +++ P Sbjct: 28753 TVKNASGIKTSAVNVKVLDTP 28773 Score = 39.1 bits (87), Expect = 1.3 Identities = 44/165 (26%), Positives = 76/165 (46%), Gaps = 10/165 (6%) Query: 757 QVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILK-PKKVKDEGVYTLKA-ENSEGI 813 Q V +P + K+ P+K+ P S S T LK P+ + + T+K+ E Sbjct: 32371 QGVKSPIASPPRVKSPPPIKSPEPIASPLRVKSPTGLKSPEPQRAKSPPTVKSPEPIMSP 32430 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + +TV+ PT PP I + + ++K I+++ V + + + WY+++ + Sbjct: 32431 KRMKSPLTVKSPTPSKEAPPKIIQQLKAEAFEDK--IRMIF-VAESSLREVVWYKDSRKL 32487 Query: 874 SPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 S S I + DG L I++V SE D G+Y C + G S Sbjct: 32488 SQSSHYQIHSSADG-TCCLYISDV-SEDDQGEYSCEIISEGGAVS 32530 Score = 38.7 bits (86), Expect = 1.7 Identities = 21/76 (27%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + L + + +T + EC+V + ++ WFR I+ ++ + M D LVI Sbjct: 12003 FTKPLEDQTVEEEATAELECEVSK-EKAEVRWFRDGQEIRKTKKYDMVADGCK-RKLVIH 12060 Query: 572 EVFPEDAGTFTCVAKN 587 + +D+ T+TC AK+ Sbjct: 12061 DCTLDDSKTYTCDAKH 12076 Score = 38.7 bits (86), Expect = 1.7 Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ ++ + G P P++ W + ++KP + + +TL I + +D T+ Sbjct: 13420 GTKIELPADITGKPEPKVKWTKADLVLKPDDRITIDTKPGH-STLSIAKTKRDDTATYII 13478 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 A N++G A++T ++ I++ P Sbjct: 13479 EAVNSSGRATATVDVNILDKP 13499 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 8/105 (7%) Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDS 897 + +TV+ I +V V P P ITW + I+ + +T NF +++ I + Sbjct: 17584 ERVTVRVGHNINVVGYVKARPDPEITWSKGESILERDKRTMLTNNF--PVVQMRIKEA-T 17640 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETE 941 D G Y A N AG++S A +T++V ++ ++L+ +Y T+ Sbjct: 17641 RADHGKYVLKAVNEAGEAS--ATITVNVLDRPGHCQNLKMTYVTK 17683 Score = 38.7 bits (86), Expect = 1.7 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 1/110 (0%) Query: 491 KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550 K D P+ +++ ++ P F G ++ E +G P P+I W + + Sbjct: 23928 KSDPRPLASPVIAKDVTIEPSFKLTFNTYSVQSGEDLKVEIPFKGRPTPKIGWMKDGQAL 23987 Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 K + + L I+E ED+G +T A N G + +I+ Sbjct: 23988 KETTRLNV-SSTATSTVLKIKEANREDSGKYTITATNNIGTVTEEVAIII 24036 Score = 38.7 bits (86), Expect = 1.7 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 6/120 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASL----PIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ++T +K+ E + V A N +G + PI +K E + P + VR G++ Sbjct: 27156 EVTELKELSEVYFRVFAKNEKGRSDFSQIGPITVKEFLIPPEANLIDYPNGELSVRIGQN 27215 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--SITILKPKKVKDEGVYTLKAEN 809 V + G P+P I W K++ +K T + I++ + ++ G YTL +N Sbjct: 27216 VNIDLPYKGKPKPIIQWMKDDVILKESEQVRFRQTENKASLIVRNARKENAGKYTLVLDN 27275 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTH 787 EK P+++ + + V +GE+ +V G P P + W N + K DG H Sbjct: 1609 EKSKPEIVLLPEPIRVFEGETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRLHYDG-IH 1667 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 + I K D G + AEN EG AE + + +++ Sbjct: 1668 YLEITDCKSY-DSGDVRVLAENPEGTAEHTVKLEIQQ 1703 Score = 38.3 bits (85), Expect = 2.3 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 9/135 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQVIEPLKS---MIVRQGE 750 IT + + Q + V+A N G S+P E E P V + +IV+ G+ Sbjct: 24299 ITGLHEEQRYEFRVIARNAAGILSVPSESTGPITAQDEIEAPSVSMDSRFKDVIIVKAGD 24358 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 S + + + G P P I W K+ K + A P T + T+L K D G + L Sbjct: 24359 SFSIDSDIAGKPLPDIVWLKDGKEIDSATPRMEIKSTITRTVLTVKDCIRVDGGHFVLSL 24418 Query: 808 ENSEGIAETSAVITV 822 N G + + V Sbjct: 24419 SNVGGTKQVPINVKV 24433 Score = 38.3 bits (85), Expect = 2.3 Identities = 36/135 (26%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Query: 795 KKVKDEGVYTLK--AENSEGIAE----TSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 KK+K+ Y + A N EG E +VI E+ E E L + + +TV+ Sbjct: 24701 KKLKENAEYNFRICAVNIEGAGEHVDVPGSVIAAEKL--EAPEIELDADLRKCVTVRASA 24758 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 T++L + P P + W + + + I G LVI NV + D+G Y Sbjct: 24759 TLRLFVTIRGRPEPEVKWKKADGTLPERAQI--EVTGSYTGLVIDNV-NRFDTGKYVLTL 24815 Query: 909 SNSAGKSSHGARVTI 923 N+ G S V + Sbjct: 24816 ENNIGSKSAFVNVKV 24830 Score = 38.3 bits (85), Expect = 2.3 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 +E+ P + + +T+K IKL ++ PVP +TWY++ + + G Sbjct: 27586 DESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVIGS 27645 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAG 913 + L I + D G Y A NS+G Sbjct: 27646 S-SLFIRDADRN-HRGIYTVEAKNSSG 27670 Score = 38.3 bits (85), Expect = 2.3 Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G++ + + G P P++TW + +K + + D TL++++ D+G + Sbjct: 28294 GNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIKISKDR-TTLLVKDAKRGDSGKYYL 28352 Query: 584 VAKNAAGFASSTTELIV 600 +NAAG + T +IV Sbjct: 28353 TLENAAGSKTFTVTVIV 28369 Score = 38.3 bits (85), Expect = 2.3 Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 11/151 (7%) Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 +E + ++P + P + + R + V K V P +I W+ N + I Sbjct: 31901 SERKYQVVTQQPFSLDHAPRITV-RMRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQI 31959 Query: 874 SPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 S N G + L I + +E D+G Y+ + +NS G++S A T+DV F Sbjct: 31960 QESHKYQFTNMSGV-LSLQINDCQAE-DTGTYRALCTNSKGEASDYA--TLDVSGGAFTT 32015 Query: 933 HLQKSYETEEGKTVILECQTSHTVSTKWYHN 963 + + + EE T I+ T T +YH+ Sbjct: 32016 YSSRRRD-EEAPTQIVPDIT----KTDYYHS 32041 Score = 37.9 bits (84), Expect = 3.0 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 8/130 (6%) Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVAR 855 + E + + A+N G+ + V P E + P + ++ + ++V+ I+L A Sbjct: 18240 RQEYEFRVSAQNQVGMGRPANVKDAVSPKEVHEHPEIDLDASLRKGLSVRAGCPIRLFAT 18299 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVASNSAG 913 + P P +TW R I I + + + ++ S DSG Y SN +G Sbjct: 18300 IRGRPAPKVTWKR----IGVDNVIRRGHVDQIDTMTFLVIPESSREDSGKYSLTLSNPSG 18355 Query: 914 KSSHGARVTI 923 + + RV + Sbjct: 18356 EKAVFVRVKV 18365 Score = 37.9 bits (84), Expect = 3.0 Identities = 21/77 (27%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V E +V G P P++ W + A +K ++ +M ++ +L + V +++G +T Sbjct: 18979 GANVCLEAEVYGKPMPKVVWKKDGAPLKLAEGMKMTQKVHHL-SLELFSVTRKESGEYTI 19037 Query: 584 VAKNAAGFASSTTELIV 600 A+N +G S+ +L V Sbjct: 19038 TAENPSGSKSANIKLKV 19054 Score = 37.9 bits (84), Expect = 3.0 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 6/115 (5%) Query: 803 YTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTI-KLVARVTRN 859 + + A NS G +++ S V ++ EP + + F + V + G I KL A VT Sbjct: 21065 FRVLARNSAGAVSKPSKPSEVIVCRDDIEEPKIDADASFSSVVVVKAGDIFKLDAHVTGR 21124 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS-EIDSGDYKCVASNSAG 913 P+PSI W ++ + + +T + + N DS D G Y ASN G Sbjct: 21125 PIPSIVWTKDGKEL--EDTAKMEIKTLDFYSCLINKDSLRRDGGAYTLTASNPGG 21177 Score = 37.5 bits (83), Expect = 4.0 Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 7/125 (5%) Query: 803 YTLKAENSEGIAE----TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 Y ++A N G ++ T ++ V+ +E E L +T K I+L A +T Sbjct: 13374 YRVRALNKLGASKPCKSTDEILAVDP--KEPPEIQLDAKLLAGLTAKAGTKIELPADITG 13431 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P + W + + ++ P + IT + + L I + D+ Y A NS+G+++ Sbjct: 13432 KPEPKVKWTKADLVLKPDDRITIDTKPGHSTLSIAKTKRD-DTATYIIEAVNSSGRATAT 13490 Query: 919 ARVTI 923 V I Sbjct: 13491 VDVNI 13495 Score = 37.5 bits (83), Expect = 4.0 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G+ I L + PEP + W + PD+ I++ D S L I K+ T Sbjct: 13420 GTKIELPADITGKPEPKVKWTKADLVLKPDDRITI----DTKPGHSTLSIAKTKRDDTAT 13475 Query: 708 YTVVAVNREGEASLPIVLKI 727 Y + AVN G A+ + + I Sbjct: 13476 YIIEAVNSSGRATATVDVNI 13495 Score = 37.5 bits (83), Expect = 4.0 Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 9/148 (6%) Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG---EASLPIVLKIK 728 E +P+E+ + + + ITN+ + QE + A+N EG AS+P K + Sbjct: 21429 ETCLPEEDEWTIVTPMAGLTATSFTITNLTENQEYKINISALNCEGVGEPASVPGSPKAE 21488 Query: 729 TGEKEPP-QVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786 P ++ L+ ++ +R ++ L V G P P I W + + L S T Sbjct: 21489 DRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPAPEIRWSREKG--EPLDRASIEIT 21546 Query: 787 HSITILKPKKVK--DEGVYTLKAENSEG 812 S T L + V D G Y L ENS G Sbjct: 21547 PSFTTLLIENVDRFDGGKYMLTVENSSG 21574 Score = 37.5 bits (83), Expect = 4.0 Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 7/112 (6%) Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNPV 861 + A N EG+ E ++V E+ PP L + + + ++ T++L V P Sbjct: 21467 ISALNCEGVGEPASV-PGSPKAEDRLLPPEIELDSDLRKVVNIRACSTLRLFVPVKGRPA 21525 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P I W R E P + + L+I NVD D G Y NS+G Sbjct: 21526 PEIRWSR--EKGEPLDRASIEITPSFTTLLIENVD-RFDGGKYMLTVENSSG 21574 Score = 37.5 bits (83), Expect = 4.0 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 8/116 (6%) Query: 712 AVNREGEASLPIVLKIKTGEKEPPQ---VIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 +V+R E++ + K E EPP E + + V G++ L A V+G P P + W Sbjct: 23238 SVSRPSESTGSVTAK---DEVEPPTYEVASEYSQILTVNAGDTFSLEASVLGKPIPAMQW 23294 Query: 769 CKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 K + V+ A + D ++ ++K D G YTL N G S + V Sbjct: 23295 FKGDVEVENSARAEIKNTDFKAVLVVKDAIRIDGGQYTLHLSNVAGSKSVSFNVRV 23350 Score = 37.5 bits (83), Expect = 4.0 Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS ++ E + G P P+++ + ++K + F D++ + +RE DAG + Sbjct: 26126 GSNLKIEIPLTGKPLPKVSLSKDGQVLKSTMRFNFDVTTDSLI-IYLRESVASDAGRYDI 26184 Query: 584 VAKNAAGFASSTTELIV 600 A N+ G S ++V Sbjct: 26185 TASNSNGTTKSFVNVVV 26201 Score = 37.5 bits (83), Expect = 4.0 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYY 560 T +E + I E + G ++ C + G P PQ+TW++ + K D Sbjct: 27584 TKDESVIPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEVDKMLVDITTVI 27643 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 ++L IR+ G +T AKN++G Sbjct: 27644 GS---SSLFIRDADRNHRGIYTVEAKNSSG 27670 Score = 37.5 bits (83), Expect = 4.0 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 17/172 (9%) Query: 1136 LVRWFKDGSEIQFSNHIQLTID---GKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAI 1188 +V+W+K+G EI ++ ++ + G +L I + D +DA Y ++G+ + Sbjct: 30591 VVKWYKNGKEI-LADGAKIKVQEFKGGYFQLVISNADENDAAAYQIRATNQLGSISTSMN 30649 Query: 1189 LTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLD---VTWYKKKSVIEDTEKFTL 1244 L VE P+ I L L V A +T++IP VTW K + +I +T + Sbjct: 30650 LDVEVPAKIYLPLHLQGMGAVHAIRGEVVTIKIPISGKPDPVVTWQKGQEIINNTAYHQV 30709 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIV 1291 I +L+ K + Y + K T +L V V PPK V Sbjct: 30710 IITRSFTSLVFLKGVQRKDSGYYIICAKNRFGMDKQTVELDVADVPDPPKDV 30761 Score = 37.5 bits (83), Expect = 4.0 Identities = 47/196 (23%), Positives = 72/196 (36%), Gaps = 20/196 (10%) Query: 1201 RLPEFILVPANTDAYL--------TVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKR 1251 R PEF L N AY+ T+ + E VTW K I+ D +K+T SD Sbjct: 31320 RPPEFTLPLFNRSAYIGEDVRFGVTITVHPEP-SVTWLKAGHRIKPDPKKYTFTSDKGLY 31378 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR---------G 1302 L+I D EYT V + K + P + + KR G Sbjct: 31379 QLMIHNVDLSDDAEYTVVANNKFGEDSCKARLNVAPHAVAEDTMRPMFKRLLANIDCVEG 31438 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 V + P P +W N K ++ + + D L I++ D+G Y++ Sbjct: 31439 QSVRFDLRVSGTPAPTLKWEKNGKPLEFRPQVEVVQEDVDYFILHIRETLIEDSGTYRVT 31498 Query: 1362 LENNCGHADVEMNVTI 1377 N G A + + + Sbjct: 31499 ATNTAGSASCQATLKV 31514 Score = 37.1 bits (82), Expect = 5.3 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 1/127 (0%) Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 A ST +L V PP + + +++GS V L V P P ++ I+ Sbjct: 89 ATSTAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSA 148 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSPPGKPNILE 1391 + D SL I + D+G Y + N+ G A + + ++ + P K + Sbjct: 149 DFQIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSGRATSTAELLVQGEEEAVPAKKSKTI 208 Query: 1392 IDSSSIN 1398 I +S I+ Sbjct: 209 ISASQIS 215 Score = 37.1 bits (82), Expect = 5.3 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 1006 TSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKY 1063 T+ +LV ET P FI++LQ V++ L+V + A VV + R+G I+ + + Sbjct: 92 TAELLVTAETAPPNFIQRLQSLTVRQGSQVRLDVRVTGIPAPVVKFYREGAEIQSSAD-F 150 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 + G + L I D G YS + S A T Sbjct: 151 QIVQDGDLYSLLIAEAFPEDSGTYSVSASNSSGRATST 188 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 7/98 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V GS I L + +P P W+ GEEI + N + D + +VL I + + Sbjct: 17191 VKAGSTIRLPALMRGLPVPTAKWVIDGEEIKSEGNTKI----DTDNFSTVLSIADCTRNH 17246 Query: 705 EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIE 739 G Y + N G ++ + VL + P ++E Sbjct: 17247 TGIYILTVSNSAGSKTVSLNVTVLDVPAAPIGPVNILE 17284 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--D 799 K++++R G ++ + + G P P TW K N +K T T L + + D Sbjct: 19372 KALVLRAGVTMRIYVPLRGRPAPKATWTKVNANLKERQGLMIKTTEWDTFLYCEDINRYD 19431 Query: 800 EGVYTLKAENSEGIAETSAVITV 822 G Y L ENS G + V+ V Sbjct: 19432 AGKYVLTLENSSGTKSYTIVVKV 19454 Score = 37.1 bits (82), Expect = 5.3 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 7/125 (5%) Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE----PLKSMIVRQGESVILSAQVV 759 +E ++ V A+N E P L I ++ P + P S + ++G +V L+ + Sbjct: 19620 KEYSFRVKAINESAEGP-PTELTILAKDQIVPPNCDLKGLPDSSYVAKEGTTVRLNIPIT 19678 Query: 760 GNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 G P P + W K + + + T+++ +++ D G +T+ NS G E + Sbjct: 19679 GIPAPAVIWKKGDVTLSDSGRISVESTTTNTVLLIRDCHRGDAGKFTIILRNSAGTKEAA 19738 Query: 818 AVITV 822 I V Sbjct: 19739 IDIKV 19743 Score = 37.1 bits (82), Expect = 5.3 Identities = 53/232 (22%), Positives = 93/232 (40%), Gaps = 26/232 (11%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQGES 751 + + + +E ++ + A N +G S P L + K+ VI P ++ V G+ Sbjct: 21744 VVGLTQGEEYSFRISATNEKG-ISDPRPLSVPVIAKDV--VIAPAFKLLFSTFSVLAGDD 21800 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAEN 809 + + V P+ + W K+ +K + + H +LK D G YT+K N Sbjct: 21801 LKIDVPYVAQPKAAVVWQKDGISLKETTRVNTEVAERHLYLLLKEATRDDVGKYTIKITN 21860 Query: 810 SEGIAETSA-VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 S G A VI +++P PP + +E+T V + P Sbjct: 21861 SAGEATADINVIVLDKP-----GPPTGPIKIEEVTADS------VTLSWQPPEYEGGCSI 21909 Query: 869 NNEIISPSETITQNFDGENIELVITNVD-SEIDSG---DYKCVASNSAGKSS 916 NN I+ +T T N+ + + T + + +G ++ A N GKSS Sbjct: 21910 NNYIVEKRDTSTTNWQIVSATVARTTTKAARLKTGCEYQFRIAAENRYGKSS 21961 Score = 37.1 bits (82), Expect = 5.3 Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 10/189 (5%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDI-AWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 PK YV S +L + + +I +++ + E+ DE + S + + + Sbjct: 22480 PKVAYVSRASVVLHWSKPIYDGGCEIQSYIVEACEVTSDEWVMCTPPSGITE--TRFEAK 22537 Query: 699 NVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGESVI 753 + + E + + AVN+ G A +P + I+ + P ++ L+ MI VR G S+ Sbjct: 22538 KLLEKHEYKFRICAVNKIGVGETADIPGSVIIEDKLEAPDIDLDADLRKMITVRAGGSLR 22597 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L + G P P + W K + + + +++ D G YTL EN+ G Sbjct: 22598 LFVPIRGRPTPEVKWGKTEGEINEAAQIDITSSFTSLVIENVNRFDSGKYTLTLENASG- 22656 Query: 814 AETSAVITV 822 SA I+V Sbjct: 22657 -TKSAFISV 22664 Score = 36.7 bits (81), Expect = 7.0 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 12/134 (8%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGT-IKLVARVTRNP 860 + + A N G +E S + + P +F++ E+ GT K+ A +T P Sbjct: 15552 FRIIAVNEIGESEPSPRTSEVRIEDIKTAPKIFMDISADELLCVRAGTPFKIPATITGRP 15611 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P +TW E ++T ++ L I VDS+++S D V + SH R Sbjct: 15612 APKVTW----EFDGKAKTEKKD------RLHILPVDSQVESTDTTSVVTVPVSLRSHSGR 15661 Query: 921 VTIDVEKVTFVKHL 934 TI + + KH+ Sbjct: 15662 YTITAKNKSGQKHV 15675 Score = 36.7 bits (81), Expect = 7.0 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 7/99 (7%) Query: 632 IPPTFSKK--PKAQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 +PP K P + YV EG+ + L + IP P + W KG+ + D +++ES Sbjct: 19649 VPPNCDLKGLPDSSYVAKEGTTVRLNIPITGIPAPAVIWK-KGDVTLSDSG-RISVESTT 19706 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 +VL I + + G +T++ N G I +K+ Sbjct: 19707 TN--TVLLIRDCHRGDAGKFTIILRNSAGTKEAAIDIKV 19743 Score = 36.7 bits (81), Expect = 7.0 Identities = 25/124 (20%), Positives = 54/124 (43%), Gaps = 2/124 (1%) Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 E ++ + A N +G ++ ++ ++ A P + +V+ +K+ AR++ + Sbjct: 22833 EYIFRVIAVNDKGKSDPR-LLASPVVAKDLAIEPTVRTKLSTYSVQVGYDLKIEARISGH 22891 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P+ITW ++ + + + + L I + E D G Y V +N G+ Sbjct: 22892 PKPTITWNKDGSALKQTTRVNVADTAHHTTLTIKDATRE-DGGMYNIVVANVLGQQEATV 22950 Query: 920 RVTI 923 + I Sbjct: 22951 EIII 22954 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 IP + K+ + G +I L C + P P + W G+E+ D+ + ++ + Sbjct: 27590 IPQIEFEAEKSLTIKAGENIKLSCSISGRPVPQVTWYKDGKEV--DK---MLVDITTVIG 27644 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 S L I + + G YTV A N G + ++++++ Sbjct: 27645 SSSLFIRDADRNHRGIYTVEAKNSSGTTKVDVLVRVQ 27681 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 3/98 (3%) Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 + KP I + E I+ G+ + G P P+V WY NG + K + + + Sbjct: 1610 KSKPEIVLLPEPIRVFE--GETAKYRCRVTGYPTPKVNWYLNGLLIRKSKRFRL-HYDGI 1666 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + I + K S + A N GT+ V L++ K Sbjct: 1667 HYLEITDCKSYDSGDVRVLAENPEGTAEHTVKLEIQQK 1704 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVAI-ESDMHMYCSVLKITNVK 701 V + I + + +P P I WL K + ++ P E + E D + L I V Sbjct: 15180 VRKNEPIEMPAEVTGLPMPKIEWL-KDDVVIEKPTEKLLFETKEIDRVTSHTKLSIPGVT 15238 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737 + +GTYTV A NR G S + +++ P V Sbjct: 15239 RLDKGTYTVTASNRLGTLSHSVTVEVLDRPTPPRNV 15274 Score = 36.3 bits (80), Expect = 9.2 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T E V G P P + WF+ ++ S ++ + D A LV+++ D G +T Sbjct: 23275 GDTFSLEASVLGKPIPAMQWFKGDVEVENSARAEI-KNTDFKAVLVVKDAIRIDGGQYTL 23333 Query: 584 VAKNAAGFAS 593 N AG S Sbjct: 23334 HLSNVAGSKS 23343 Score = 36.3 bits (80), Expect = 9.2 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 5/105 (4%) Query: 727 IKTGEKEPPQVIEPLKSMIV--RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784 IK EP + + ++ + G S + + G P P +TW +K S Sbjct: 28270 IKEPRIEPTADLSSIDKQLITCKTGNSFAIDIPISGRPAPKVTWKLEEMKLKETDRVSIK 28329 Query: 785 DTHSITILKPKKVK--DEGVYTLKAENSEGIAE-TSAVITVEEPT 826 + T L K K D G Y L EN+ G T VI + PT Sbjct: 28330 ISKDRTTLLVKDAKRGDSGKYYLTLENAAGSKTFTVTVIVIGRPT 28374 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/107 (21%), Positives = 44/107 (41%), Gaps = 6/107 (5%) Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 +V T + P IT+ + H+V G T ++ P + W+ NG +++ Sbjct: 31906 QVVTQQPFSLDHAPRITVR----MRSHRVPCGQNTKFTLNVQSKPDANIQWFHNGQQIQE 31961 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +Y T ++I + + + Y +N+ G +S TL V Sbjct: 31962 SHKYQFTNMSGVLSLQINDCQAEDTGTYRALCTNSKGEASDYATLDV 32008 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/128 (19%), Positives = 51/128 (39%), Gaps = 3/128 (2%) Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 R T + L +++++ ++ V+ ++ KI+ + G + D Sbjct: 32103 RHTTSEKHVSSESKLKESETSAEVSVKKIKATLSAKILTKPHSLIVSEGDSARFVCDIDG 32162 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P W+ + + S ++L I VE +D G Y + +EN+ G + Sbjct: 32163 EPAPTVTWMHEGRTVVSSHRIHVSTTQYKSTLEISSVEYSDEGNYTVVVENSEGKQEARC 32222 Query: 1374 NVTILDKP 1381 + I +KP Sbjct: 32223 TLAI-NKP 32229 Score = 36.3 bits (80), Expect = 9.2 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 KE P+ I++L+ ++K I E S +VVW +D + + Sbjct: 32446 KEAPPKIIQQLKAEAFEDKIRMIFVAE--SSLREVVWYKDSRKLSQSSHYQIHSSADGTC 32503 Query: 1073 KLYIRNTSVHDEGEYSCILRDE 1094 LYI + S D+GEYSC + E Sbjct: 32504 CLYISDVSEDDQGEYSCEIISE 32525 Score = 36.3 bits (80), Expect = 9.2 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPEDAGTF 581 G + C G P P I W R + +D ++ + +++ TL+I V DAG + Sbjct: 32676 GKVLTVACAFSGEPAPHIEWSRGGKKLPGEEDSSRFHIETTEDLTTLIITGVKETDAGAY 32735 Query: 582 TCVAKNAAGFASSTTELIVEA 602 T N G +T + + + Sbjct: 32736 TLKLSNEHGSDLATVTISIRS 32756 >UniRef50_UPI0000F2186B Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 11202 Score = 311 bits (764), Expect = 1e-82 Identities = 330/1441 (22%), Positives = 581/1441 (40%), Gaps = 81/1441 (5%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +LEG P F+ K + E +++L C V+ + W EI P +N+ + + Sbjct: 3376 VLEG-EPYFTTKLQDYTAVEKDEVVLMCE-VSKSSAQVKWFKDTNEITPSKNVLIKADGK 3433 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 +L + +K G Y + + A L I E+ ++ PL S+ V Sbjct: 3434 KR----ILTVKKAEKGNIGEYVCDCGSDKTAAKLNI-------EERDIKISRPLYSVEVT 3482 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYT 804 + E+ ++ W + P K +G H + IL ++ G Sbjct: 3483 ETETARFETEI-SEEDVHGHWKLKGDALHQSPDCEIKEEGTKHML-ILYNVRMDMAGAVD 3540 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N A+++A + V+ T P +++TV T ++ +P + Sbjct: 3541 FSAAN----AKSTAQLRVKARTIGLLRP------LRDVTVTAGETATFDCELSYEDIP-V 3589 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W+ + + PS+ + +G L + +V ++G+ K A + + A++T++ Sbjct: 3590 EWFVGSTKMEPSDRVVTRAEGRLHSLTLRDVIMT-EAGEVKLTAKDFVTQ----AKLTVN 3644 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983 V F K L+ EE T ILEC+ S KW+ + +EI E++ EGR Sbjct: 3645 EPPVEFSKPLEDQ-TVEEEATAILECELSREKADVKWFRDGQEIRKTKKHEMVAEGRIRR 3703 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D C K+ +TS L V+ EF + L D EVKEK+ A E E++ E Sbjct: 3704 LIIKDCSLDDSKTYTCDAKEFKTSAFLNVEPPFVEFSKPLHDVEVKEKESAKFECEVSRE 3763 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 +A V W +DG I+ K KY+ +G R L I DE EY C R + +TVV Sbjct: 3764 SAKVRWFKDGAEIR-KGKKYEIIAKGLQRILIISKAVFDDEAEYECDARTSKSSGMLTVV 3822 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 E L N + + + E++K A V W K EI + DGKK+ L Sbjct: 3823 EEEARFTKNLANVEGTETDSIKMVCEVSKPSAEVTWHKGDQEIPEGGRYEHVADGKKRIL 3882 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 I D +DDAGEY C++ S+ T L + E + F R P+ A + + Sbjct: 3883 IIQDLRMDDAGEYHCKLPASETTGTLKISELAAEFIAR-PQNQETVEGEKAEFVCSVSKD 3941 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 +V W+K + +K+ ++ D K+R LII+ C D+ +T + K++ L V Sbjct: 3942 NYEVKWFKGDKELTTDDKYEIVVDGKRRALIIKNCELKDEGAFTANIGSVKASANLLV-- 3999 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 +E +I+ ++ ++K G ++ L + + +W+ N++ + + + Sbjct: 4000 IE-KLRIITPLKDTQVKEGQEIVLNCEVNS-EGAKAKWLKNNETMFESSKFVMAQRDTVF 4057 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 SL IK E +D Y + L N G A N+++ ++ +P EI+ I + Sbjct: 4058 SLRIKAAEKSDEASYTITLTNQRGEQAKCSANISVHEEALKIIEPLEDCEIEEKK-TITF 4116 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 N N T+ ++ QEI ++ I + + K + ++ +K S Y V + Sbjct: 4117 TCKVNRPNVTV-QWMKAGQEITLSKRILYR-VDKDKHTL-TIKDCSLADEGEYTV----V 4169 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + + T +I E L++ T ED E TC + V WYR+G++ Sbjct: 4170 AGTDKATAEL-IISEAPADFAA---QLRDQTITEFEDAEFTCKLSK-EKAHVKWYRNGRE 4224 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 ++ + R +C + + + +++ PV I Sbjct: 4225 IREGPRYHLERDGKECKLVVKECRPDDECEYACGVEDKRSRARLFVEEIPV-EIVRPPTD 4283 Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 G + + A + EV W +N + +Y + ++ K +++ E++ Sbjct: 4284 VFEPPGSDIVFEAELNK-DRVEVKWMRNNMIIVQGDKYQMISEGKVHRLQVCEIRPRDQG 4342 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 +Y I A + +E+ K + ++ + + V P D ++ Sbjct: 4343 EYRIVAKEKDARAKLELAAIPKIKTTDQN---LVTDAGKPFVMAV---PYDAYPRAEAEW 4396 Query: 1702 AIEKHE-PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760 + P N D + Y +++ ++ + ++++ +N G EA + ++ Sbjct: 4397 FFDDISLPGQN-----IDTSNERTEYRLKEPKKSDQGRYKIVIKNKHGTGEAFINLDVI- 4450 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXX 1819 DVP D E V + W E +GGS I+ Y VE + +K W Sbjct: 4451 ----DVPGPVKNLHVVDTADGE-VSLAWEEPESDGGSKILAYVVERRDVKRKTWTMATDR 4505 Query: 1820 XXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + L + Y FR+ ARN +G T+D+ + P P+ F+V Sbjct: 4506 ADIPEYCVGGLHRDNMYFFRVCARNRVGNGETVTTDEAVQAKNKFDVPDAPQKFMVGVVN 4565 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 T+ W P +GGS +T+YIIE + W + V + ++ E E IF Sbjct: 4566 RFGATVSWEPPLFDGGSEVTSYIIELRDRTSVKWEPAMVVKAEDLTATLSDVVENKEYIF 4625 Query: 1939 RISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 R+ AEN G+ P+ + V++ PSPP + V SW TP +GG+ Sbjct: 4626 RVRAENKAGIGQPSAATDPVKIMDPIERPSPP-LNFNYTNQTRDSVQLSWETPISNGGSM 4684 Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + GY I + W+ L + + L Y R+ A N G+SEP ++ Sbjct: 4685 ITGYIIEKCEDGTDKWLRCNARLCPDLYYRVSGLKFGQKYHYRVCAENAAGVSEPADAIG 4744 Query: 2058 P 2058 P Sbjct: 4745 P 4745 Score = 281 bits (688), Expect = 2e-73 Identities = 213/770 (27%), Positives = 335/770 (43%), Gaps = 42/770 (5%) Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSIN 1398 S S S+ IK G+Y + +N+ G + V +LD P P G P E + S S Sbjct: 7813 SISCSMVIKDCTRAQRGVYTITAKNDGGEVKKSVIVEVLDVPGPVGVPFTAENLTSESCK 7872 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVN 1457 + W P++ G S I Y++E +E + W S Q ++ NL +Y FR AVN Sbjct: 7873 LNWFFPDDDGGSAISNYIIEKREAERKAWTSCSYTAGRQNAVVNNLVLKKAYFFRVAAVN 7932 Query: 1458 EVDISDASETTEYYKVIKET--------KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 + + ++ T VIK+ +++ + K ++T +P ++ + + + Sbjct: 7933 AIGVGPFNQ-TACEIVIKDRINVPDRPEELEVTAITKDHISLTWKPPKNDGGSEVISYIL 7991 Query: 1510 QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------- 1562 + + T +D T E R ++ A N+ G + S Sbjct: 7992 EAR-TIGKDKFVRLTKDKLMERRYTYDGLREGETYE--FRVSAVNEVGPGKPSFSTKPIT 8048 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 C ++ P I + D K +VG+ + + G P P + W ++ +L+ D Sbjct: 8049 CKDELEP-PTIELDFRD-KVVVRVGESFALQGRYTGKPAPSITWSRDDKELKADNHIKFK 8106 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 T + I + +R HS KY + N G + V D+P PEGPV+ E+ R+ Sbjct: 8107 NTLTTMCLGIVKAQRGHSGKYCVTVENCTGARKGICNVIVADRPLPPEGPVVFDEVHRDH 8166 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRV 1741 + I WKPPLDDGG E++ Y IEK + + + W V +T+C + KL E EY+ R+ Sbjct: 8167 MVISWKPPLDDGGSEISNYIIEKRDVNRDMWTTVTSA--TTKTHCKVPKLVEGREYILRI 8224 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 A+N G S+ LESE + K VP + N+S + W ++GG PI + Sbjct: 8225 SAENMYGISDPLESEEMKAKDLFRVPE-APEQPTVKDVYNDSALVIW-NRPRDGGKPITN 8282 Query: 1802 YKVEIKQ-EGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 Y +E K+ K+W A R+Q+L Y+FR+ A NEIGT P I Sbjct: 8283 YILEKKEPSAKRWSRATRDPIYPATQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPI 8342 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 + PS P + T SV+L W P +G I Y+IE++ W K Sbjct: 8343 LAKDPIVLPSPPVLPEAVDKTKDSVSLSWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANE 8402 Query: 1918 VGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLE 1974 S + + N+ E +E FRI A N G S P + V++ P PP L Sbjct: 8403 TPESCPDTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDKPGPP-RNLA 8461 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 I + S +W PE DGGA + Y + +DV W+ V L + L E Sbjct: 8462 ISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAAS-KKLSLMAQYLMEG 8520 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVI-----PGEGSHADEEPGEQTEV 2079 Y+ R+ A N+ G S +E+++P K + PG + ++TEV Sbjct: 8521 TQYLFRVAAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDADKTEV 8570 Score = 246 bits (602), Expect = 5e-63 Identities = 172/617 (27%), Positives = 272/617 (44%), Gaps = 25/617 (4%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 LDKP PP I EI S S + W +PE+ G + I +Y+V+ +++ W+ V +K Sbjct: 8451 LDKPGPPRNLAISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAASKKL 8510 Query: 1438 TSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + + Q L + Y FR A N+ S ET + K + + P K L ++ + Sbjct: 8511 SLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAVDP--LYPPGPPKNLHHVDADKT 8568 Query: 1497 E---DIELTCIFGGVPQPKVTWY--RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 E E GG ++T + ++ T T++ Y+ Sbjct: 8569 EVWLQWEWPDRTGG---SEITGFIVEHQEEGATDWVTFKTVSNPQCHVTGLVEGKTYRFR 8625 Query: 1552 AFNDHG----EVETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPE 1603 + + +TS + Q+K + D+K K G L+ AV+ GIP P Sbjct: 8626 VKSQNAIGISRPDTSVPITCQEKTLAPTIEVDVKLIEGLVVKAGSTILLPAVMLGIPTPT 8685 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 W GN+L+ + ++ I T+ ++ + I E R+ S +Y++ SN AG+ SV + + V Sbjct: 8686 AKWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSNPAGSKSVALHVTVL 8745 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN--NRWIKVADVDR 1721 D PS P GPV + E++ + + I+W+ P DDGG L Y +EK + W V+ Sbjct: 8746 DVPSAPVGPVNILEVTPDHMIIQWRAPKDDGGSPLMSYVVEKKDVKKPWEPWSVVSSGST 8805 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 + + +L + EY+ RV A+N +G LES P + K D P +N Sbjct: 8806 STKAK-VPRLEKGREYIVRVRAENKIGIGAGLESPPTIAKQMFDPPGPPGQPTCSDITEN 8864 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRI 1839 +V ++W E +GGSP+ Y VE ++ KW R + + +Y+FRI Sbjct: 8865 -AVTVSWAEPETDGGSPVSGYIVERREMTGKWIRVNKTPVLDIRYRVCGLFEGNSYEFRI 8923 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 +A N G S P D + + +TPP P N + + + L WT+P +GGSPI Sbjct: 8924 FAENVAGVSQPSYPSDPMKAKRPITPPGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILG 8983 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 Y++E + W KI + + E E FRI A N VG P E L Sbjct: 8984 YVVEIQRSGSAQWDKINKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTETVL 9043 Query: 1960 EKHATVPSPPTAPLEIR 1976 K VP T + R Sbjct: 9044 AKDILVPPEVTVDVACR 9060 Score = 237 bits (580), Expect = 2e-60 Identities = 185/723 (25%), Positives = 316/723 (43%), Gaps = 48/723 (6%) Query: 1364 NNCGHAD---VEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVV 1417 N CG + ++ V + + P P +L + + SI + W+ P G + + Y+V Sbjct: 4927 NKCGPGEPAYIDEPVNVSSPATVPDPPELLKWRDKSAKSIFLLWEPPRYDGGAAVKGYIV 4986 Query: 1418 EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + + T +W + + I + + + L Y +R AVN + S + T+ +++ Sbjct: 4987 DKCQRGTDKWEACGDPIPELKFQVTGLIEGQWYAYRVRAVNRLGASRPCKATD--EILAV 5044 Query: 1477 TKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TY 1529 + P ++ K L +T I+L G P+P+V W + LK + T Sbjct: 5045 DPKEPPEIQLDAKLLAGLTARAGTKIDLPADVLGKPEPRVKWTKADLVLKPEERITIDTK 5104 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-------VITISNEDI-- 1580 Y A N G + V I KP + I+NE Sbjct: 5105 PGHSTLSIANTTRSDTATYIIEAVNTSGRATATVDVNILDKPGPPAAFDISEITNESCCL 5164 Query: 1581 --KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 G + ++E P + W K ++ T + T ++ +KE Sbjct: 5165 AWNAPRDDGGSPVANYIVEMRPTDKEEWQKLSATIKQ------TAFKATKLVPLKE---- 5214 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV---YDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 + + + E GT + V + +D P P V +I+R++VT+ W P +DGG Sbjct: 5215 YVFRVSAENQYGIGTPAEHVPIVAKYSFDTPGAPTR-VQPSDITRDAVTLTWYEPDEDGG 5273 Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754 +T Y +E+ +P+ ++WIK + T+ ++ L +Y FRV+A+N G + ++E Sbjct: 5274 SPITGYWVERFDPETDKWIKSNKLPIKDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVE 5333 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW 1813 ++P++IK +D P I S + W E +GG+ I Y +E+++ G ++W Sbjct: 5334 TDPVLIKDPID-PPWAPGKPFVKDIAKTSADLQWTRPEHDGGAKIESYIIELQKTGTEEW 5392 Query: 1814 -KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 + ++ L Y FR+ A N G S P D + + L P+ PR Sbjct: 5393 VRVAEDVPTTEHSLKGLMEKQEYSFRVKAINVAGESEPSDPSDPVVCKERLYVPNPPRWL 5452 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE 1932 V T + LKWTEP+S+GGSPITNY++E + V+ ++W + T ++ + + E Sbjct: 5453 EVVNITKINCDLKWTEPDSDGGSPITNYVVEKRDVRRRTWQAVDTTVKDT-KYTVTPLSE 5511 Query: 1933 KDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 +FR++AEN VG+S E + L K T P PP A L + V V W P Sbjct: 5512 GSLYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYA-LTVVEVSKRHVDLKWEPPN 5570 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DGG P+ Y I ++ T W++ GK K+ + D+ E ++ A NE G+ Sbjct: 5571 SDGGRPITKYVIEKKEKVGTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGH 5630 Query: 2052 PLE 2054 P E Sbjct: 5631 PSE 5633 Score = 230 bits (562), Expect = 4e-58 Identities = 196/794 (24%), Positives = 344/794 (43%), Gaps = 52/794 (6%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVV 1284 W + ++ + + + + LII+ + D EY+ V ++ + T K+ + + Sbjct: 10026 WKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDI 10085 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN--SKIIKKCKHTK----PSI 1338 PP E + I SD+ ++ +P ++ N + +++KC ++ ++ Sbjct: 10086 PGPP-----EPPFEI---SDIDSDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWVTAL 10137 Query: 1339 DS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-P-SPPGKP---NILEI 1392 S A I K+ I+++R EN G +D + ++ K P PG+P I ++ Sbjct: 10138 SSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDPLASERMVAKFPFDVPGEPLNCRINKV 10197 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450 + + + WD+PE+ G S + Y +E +E ++ W+ + + T+ L Y Sbjct: 10198 NKDCMFVAWDKPESDGGSPVTGYYIERKERNSLLWVKANDSVVRTTEYPCAGLIEGLEYT 10257 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KN----ITTEPNEDIELTC 1503 FR A+N S+ T++ + T + +P + L KN + T+P D Sbjct: 10258 FRVSAINRAGQGKPSKKTDF--ITARTPVDAPGKPEVLDVTKNAVSLVWTKPKNDGGSKI 10315 Query: 1504 I---FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 I + P TW R + + + E+ Sbjct: 10316 IGYYVEAMRLPGDTWVRCNTSSQNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEIT 10375 Query: 1561 TSCVVGIQQKPV-ITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 +V + P I +S + K K G + + A + G P P+V W KNG L+ DKE Sbjct: 10376 DPILVSAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKE 10435 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 + ++ K + + + + H+ Y I A+N +G ++ E+ LK+ D P P V + EI Sbjct: 10436 FKMSQKRHLFSLSLDAVTKLHAGNYGIHAANASGNTTAEIQLKILDIPG-PPASVKLDEI 10494 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEY 1737 + V + W+ PL DGG +T Y ++K E W +V A + RD +++L E EY Sbjct: 10495 LSDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEY 10554 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV A+N G +A+ SEP+V + VP I E + ++W +G S Sbjct: 10555 QFRVRAENHYGTGDAIISEPVVARNPFTVPG-ACDPPVLTNITKEHMTVSWKEPSDDGKS 10613 Query: 1798 PIIDYKVEIKQEGKK--WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 PI+ Y VE K+E K+ W + LS Y+FR+ A N+ G P Sbjct: 10614 PILGYLVE-KRETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFRVIAVNKAGLGKPSDP 10672 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + + L PP P + ++T+ ++ L WT+P ++GGS I Y++E K + W Sbjct: 10673 SNAASALDPLYPPGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVECKRINTTDWI 10732 Query: 1914 KI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 + V + + + E E R+SA N +G S P E + K V P A Sbjct: 10733 RCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPEKHIAKDVFV--TPEAE 10790 Query: 1973 LEIRMVGSNIVMTS 1986 L+ + +V+T+ Sbjct: 10791 LDAEL-KDTLVLTA 10803 Score = 222 bits (542), Expect = 1e-55 Identities = 196/832 (23%), Positives = 345/832 (41%), Gaps = 42/832 (5%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP-PKIVDYEREYRIKRGSDVTLL 1308 +++I+ CT + YT + K V EV++ P P V + E + Sbjct: 7817 SMVIKDCTRAQRGVYTITAKNDGGEVKKSVIVEVLDVPGPVGVPFTAENLTSESCKLNWF 7876 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 +I+ + ++ T S + + + + A +++ N G Sbjct: 7877 FPDDDGGSAISNYIIEKREAERKAWTSCSYTAGRQNAVVNNLVLKKAYFFRVAAVNAIGV 7936 Query: 1369 ADVEMN---VTILDKPSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEI 1422 + I D+ + P +P LE+ + + I++ W P+N G S +I Y++E + I Sbjct: 7937 GPFNQTACEIVIKDRINVPDRPEELEVTAITKDHISLTWKPPKNDGGSEVISYILEARTI 7996 Query: 1423 DTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 +++ + + + + + L+ +Y FR AVNEV S +T+ + + +++ Sbjct: 7997 GKDKFVRLTKDKLMERRYTYDGLREGETYEFRVSAVNEVGPGKPSFSTK--PITCKDELE 8054 Query: 1481 SPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXX--- 1535 PT+E ++ + E L + G P P +TW RD K+LK ++N Sbjct: 8055 PPTIELDFRDKVVVRVGESFALQGRYTGKPAPSITWSRDDKELKADNHIKFKNTLTTMCL 8114 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI---TISNEDIKQKHKVGDEWLV 1592 Y N G + C V + +P+ + +++ + H V W Sbjct: 8115 GIVKAQRGHSGKYCVTVENCTGARKGICNVIVADRPLPPEGPVVFDEVHRDHMV-ISWKP 8173 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 G I K + D +T+ + ++ +L I A N G Sbjct: 8174 PLDDGGSEISNYIIEK--RDVNRDMWTTVTSATTKTHCKVPKLVEGREYILRISAENMYG 8231 Query: 1653 TS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 S S E+ K ++ P PE P + +++ +S + W P DGG +T Y +EK E Sbjct: 8232 ISDPLESEEMKAKDLFRVPEAPEQPTV-KDVYNDSALVIWNRP-RDGGKPITNYILEKKE 8289 Query: 1708 PDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALD 1765 P RW + D Y +Q+L E CEY FRV A+N +G + ++ S+PI+ K + Sbjct: 8290 PSAKRWSRATRDPIYPATQYRVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDPIV 8349 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW----KXXXXXX 1820 +PS +SV ++W +G I Y +E ++ G +W + Sbjct: 8350 LPSPPVLPEAVDK-TKDSVSLSWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANETPESCP 8408 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 + L +QFRI A N G S P + + + L P PRN +SE TS Sbjct: 8409 DTKFVVTNLPEGEEFQFRIMAVNAAGKSEPAYVKEPVKVHDRLDKPGPPRNLAISEITSE 8468 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 S L W +PE +GG+ I++YI++ K V ++W + + + + E + +FR+ Sbjct: 8469 SAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAASKKL-SLMAQYLMEGTQYLFRV 8527 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +AEN G S E+ P P L V W P+ GG+ + G Sbjct: 8528 AAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDADKTEVWLQWEWPDRTGGSEITG 8587 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + + ++ T W V V+ + ++ L E TY R+ ++N IG+S P Sbjct: 8588 FIVEHQEEGATDW--VTFKTVSNPQCHVTGLVEGKTYRFRVKSQNAIGISRP 8637 Score = 218 bits (532), Expect = 2e-54 Identities = 140/457 (30%), Positives = 218/457 (47%), Gaps = 16/457 (3%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPE---GPVIMREISR 1680 K + R+K L K+ + A N AG SVE + P P G +++I++ Sbjct: 5300 KDTTFRVKGLPTKKKYKFRVLAENLAGQGKPSVETDPVLIKDPIDPPWAPGKPFVKDIAK 5359 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 S ++W P DGG ++ Y IE + W++VA+ D + ++ L E EY FR Sbjct: 5360 TSADLQWTRPEHDGGAKIESYIIELQKTGTEEWVRVAE-DVPTTEHSLKGLMEKQEYSFR 5418 Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A N G SE + S+P+V K L VP+ I + + W + +GGSPI Sbjct: 5419 VKAINVAGESEPSDPSDPVVCKERLYVPNPPRWLEVVN-ITKINCDLKWTEPDSDGGSPI 5477 Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 +Y VE + ++ W+ + LS + Y FR+ A N +G S +D + Sbjct: 5478 TNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSV 5537 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 T T P P V E + R V LKW P S+GG PIT Y+IE K G W K Sbjct: 5538 LAKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKSGK 5597 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 G ++ + ++ E E+ F++ AEN GV P+E + + A SPP+ PLE+++ Sbjct: 5598 TSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAI--SPPSPPLEVKI 5655 Query: 1978 VGSN--IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD-LSEN 2034 V ++ + +W PE +GG+P+ GY++ + + WM + V L+F + + Sbjct: 5656 VDASREHINITWKAPEKNGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPE 5715 Query: 2035 HTYMIRIYARNEIGLSEPLE-SDEPFKVIPGEGSHAD 2070 Y++R+ A N IG+S+P E SD F P D Sbjct: 5716 KKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTID 5752 Score = 210 bits (513), Expect = 3e-52 Identities = 172/690 (24%), Positives = 281/690 (40%), Gaps = 40/690 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 I+ G + L P P +W + K +H + KS++L+IKK TD GIY Sbjct: 6483 IRAGETLRLPAVVTGRPVPEVKWTKDGAEPDK-EHVVIEAEIKSSTLSIKKALRTDHGIY 6541 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 ++ N G V + V ++D P P + + I++ W +P + G S I+ YVVE Sbjct: 6542 QITGTNPSGTKSVSVKVDVMDVPGPVVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVE 6601 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 ++ + + + I L Y FR A N+ + E V + Sbjct: 6602 RKDAKMHIYRQPLEVAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDPKGV 6661 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-----RDGKKLKTAKATYENRX 1533 +P + + E GG P + +Y +D + A Sbjct: 6662 PSAPEKLRYTERTKNTITLTWEAPRSDGG--SPIIGYYIEKMRQDSNEYDVANRNLCKDL 6719 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVIT----ISNEDIKQKH 1584 ++ A N+ G E S + + + P + ++ I + Sbjct: 6720 TITLENLTENMMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRK 6779 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK------TSVIRIKELKRS 1638 E + A I G+P P W KNG ++ E E+ T+ I I E R Sbjct: 6780 GAAIE--IPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQ 6837 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 + Y + A+NT G + + + D+P P +++ +I ES + W P D+GG +L Sbjct: 6838 DTGMYKLTATNTRGVGQRTMRVDILDRPLPPRN-IVVSDIKAESCYLTWDAPEDNGGSDL 6896 Query: 1699 TKYAIEKHEPDNNR--WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 T Y +EK + + W ++ D Y + KL Y F++ A+N G S+ ESE Sbjct: 6897 TNYIVEKRDASKKKSDWDQLTCCIMD-RRYGVYKLEAYGTYQFQIKAENKYGISDGCESE 6955 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKX 1815 +V+K +P S+ +TW P + NGGS I Y +E ++ G W Sbjct: 6956 KVVLKDPFGLPGPPQRPRIISHT-RSSMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSR 7014 Query: 1816 XXXXXXXXARIQKLSINTT-------YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868 ++ L N Y+FR+ A+N G P + + + PPSQ Sbjct: 7015 VNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATECVFALDPRNPPSQ 7074 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHC 1926 P VV++ + SV+L WT P+ +GGSPI YI+E + W +I T + + + Sbjct: 7075 PPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYT 7134 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + +KE + FRI A N G S P+ S Sbjct: 7135 VPGLKENKKCRFRIVAVNAAGESEPSPRTS 7164 Score = 208 bits (508), Expect = 1e-51 Identities = 139/483 (28%), Positives = 222/483 (45%), Gaps = 19/483 (3%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSK 1642 K GD + A + G P PEV W K G+ + K + + T+ +++ +R + K Sbjct: 9359 KAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGK 9418 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y I A+N AGT S E + V D+P P + + +IS + + W+ P DDGG E+ Y Sbjct: 9419 YIITATNAAGTCSAEAKVNVLDRPG-PIRDLKVSDISIDRCKLAWEIPEDDGGCEIYNYI 9477 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 IEK E W + + + +L E EY+FRV A+N +G A+ESE I+ +T Sbjct: 9478 IEKCEAKRGVW-SIHSAAIITNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESIIART 9536 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821 P I +++ + W + +GG PI Y +E K+E +W Sbjct: 9537 QFSRPGAPDAPEVTK-ITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVKSPY 9595 Query: 1822 XXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 ++ S+ N YQFR+ A NEIG T + PP N V++S+ Sbjct: 9596 AGTQMTVTSLLPNHEYQFRVKAENEIGVGDASKPSRTFTARDPVEPPGPVSNLKVTDSSK 9655 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSV--HEHCIENIKEK 1933 S+TL WT+P +GG+P+ Y++E + KG K V + E + ++ EK Sbjct: 9656 TSITLAWTKPTYDGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEK 9715 Query: 1934 DEIIFRISAENT----VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 E FR++ +++ + VS P ++V + P LE+ + + +W Sbjct: 9716 LEYEFRVTRDDSGKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTDMTMSSCNLTWSP 9775 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 PE DGG+ + Y + R++ + W V K +V F I +L Y R+ A NE G Sbjct: 9776 PETDGGSNVTHYIVEKREIDRKTWATV-KANVEKTTFKISNLVPGTEYYFRVVAVNEYGP 9834 Query: 2050 SEP 2052 P Sbjct: 9835 GVP 9837 Score = 195 bits (475), Expect = 1e-47 Identities = 169/698 (24%), Positives = 279/698 (39%), Gaps = 40/698 (5%) Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTS 1439 PGKP +L++ +++++ W +P+N G S II Y VE + W+ S +N+ + + + Sbjct: 10287 PGKPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSSQNVPREEYT 10346 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTEPN 1496 L+ ++Y+FR A V+IS SE T+ ++ + P +E + K + + Sbjct: 10347 ATGLEEGANYQFRVIAKTAVNISRPSEITD--PILVSAENVPPRIELSVQMKKMLPVKAG 10404 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552 D+ L G P PKVTW ++G+ LK K + + Y A Sbjct: 10405 SDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFSLSLDAVTKLHAGNYGIHA 10464 Query: 1553 FNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N G ++ I P +E + + K+ W V G P + K Sbjct: 10465 ANASGNTTAEIQLKILDIPGPPASVKLDEILSDRVKL--SWEAPLVDGGSPITNYVVDKR 10522 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSK 1668 + + T+ ++ L H ++ + A N GT ++ V + P Sbjct: 10523 ETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYGTGDAIISEPVVARNPFT 10582 Query: 1669 PEG---PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 G P ++ I++E +T+ WK P DDG + Y +EK E W K+ T Sbjct: 10583 VPGACDPPVLTNITKEHMTVSWKEPSDDGKSPILGYLVEKRETKEVNWTKINRKPLLERT 10642 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNES 1783 + L+E +Y FRVIA N G + S+P +ALD P N + Sbjct: 10643 LEVGGLSEGAQYEFRVIAVNKAGLGK--PSDPSNAASALDPLYPPGPPISPKAIDTTNST 10700 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW---KXXXXXXXXXARIQKLSINTTYQFRI 1839 + +TW +GGS I+ Y VE K+ W + L N+ YQ R+ Sbjct: 10701 IKLTWTKPANDGGSDILGYLVECKRINTTDWIRCNVPKNLQDTNYVVTGLLENSEYQLRV 10760 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N+IG S P +K P + + ++ + K G PI Sbjct: 10761 SAVNKIGFSQPCEVPEKHIAKDVFVTPEAELDAELKDTLVLTAGSKMKLHAKIKGRPIPR 10820 Query: 1900 YI-IEFKT-VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + T +K + I T C+E + D + ++ ++ G+ + T Sbjct: 10821 VTWAKMNTNIKDRQGIIIKTTDTDTLV-CVEKVNRYDAGKYILNLDSVSGMKMYTV---- 10875 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + K P PP L I+ + W P DGG+ + GY + RD + W V Sbjct: 10876 -IVKVLDTPGPP-LNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVT 10933 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 T F I DL +Y R+ A+N+ G+ EP E+ Sbjct: 10934 TSCTKT-SFKIEDLEPGRSYCFRVLAQNQYGIGEPCET 10970 Score = 188 bits (458), Expect = 1e-45 Identities = 198/885 (22%), Positives = 344/885 (38%), Gaps = 51/885 (5%) Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 Y+K IE + ++ E ++ ++ + ++A K + V+ P K Sbjct: 8389 YQKPGAIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMAVNAAG--KSEPAYVKEPVK 8446 Query: 1290 IVDYEREYRIKRG---SDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSID 1339 + D + R S++T Y + +P D+ +IV K + Sbjct: 8447 VHDRLDKPGPPRNLAISEITSESAYLTWQKPEDDGGAVISHYIVQKKDVAAENWVPVCAA 8506 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTI--LDKPSPPGKPNIL---EID 1393 SK SL + + ++++ EN G A VE N I +D PPG P L + D Sbjct: 8507 SKKLSLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAVDPLYPPGPPKNLHHVDAD 8566 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 + + + W+ P+ TG S I ++VE+QE T+W++ K ++ Q + L +YRFR Sbjct: 8567 KTEVWLQWEWPDRTGGSEITGFIVEHQEEGATDWVTFKTVSNPQCHVTGLVEGKTYRFRV 8626 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQ 1510 + N + IS + + + K +PT+E K ++ + + I L + G+P Sbjct: 8627 KSQNAIGISRPDTSV---PITCQEKTLAPTIEVDVKLIEGLVVKAGSTILLPAVMLGIPT 8683 Query: 1511 PKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---C 1563 P W +G +LKT T N Y N G + Sbjct: 8684 PTAKWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSNPAGSKSVALHVT 8743 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 V+ + PV ++ ++ H + +W G P + K K + +++ Sbjct: 8744 VLDVPSAPVGPVNILEVTPDHMI-IQWRAPKDDGGSPLMSYVVEKKDVKKPWEPWSVVSS 8802 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNT----AGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 ++ ++ L++ + A N AG S K P P G +I+ Sbjct: 8803 GSTSTKAKVPRLEKGREYIVRVRAENKIGIGAGLESPPTIAKQMFDPPGPPGQPTCSDIT 8862 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 +VT+ W P DGG ++ Y +E+ E +WI+V Y + L E Y F Sbjct: 8863 ENAVTVSWAEPETDGGSPVSGYIVERREM-TGKWIRVNKTPVLDIRYRVCGLFEGNSYEF 8921 Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 R+ A+N G S+ + S+P+ K + P + W ++GGSP Sbjct: 8922 RIFAENVAGVSQPSYPSDPMKAKRPI-TPPGPPSNIKLKDWSKSYADLVWTKPSRDGGSP 8980 Query: 1799 IIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 I+ Y VEI++ G +W R+ L+ Y+FRI A N++G P + Sbjct: 8981 ILGYVVEIQRSGSAQWDKINKDLIKFCAFRVPGLNEGIEYRFRIKASNKVGDGEPRELTE 9040 Query: 1856 KITIGKTLTPPSQPRNFVVSE-STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 + L PP + + T R+ + G + V G+ Sbjct: 9041 TVLAKDILVPPEVTVDVACRDLLTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRT 9100 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + + E I++ D + I A+N+ G ++Q+ + +P L+ Sbjct: 9101 EMNNNFPLVELVIQDAVRADYGKYAIQAKNSSG-----QAQATIIVNVLDIPG-ACQNLK 9154 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 + V + M SW PE +GG + Y I R ++ W V D T + L +N Sbjct: 9155 VAYVTKDSCMVSWENPEDNGGTEITNYKIECRQPSQRGWTVVSS-DC-TKRLVKAPLVQN 9212 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 Y R+ A N+IG P ES P + + E + TE+ Sbjct: 9213 CEYFFRVSAENKIGAGPPTESKTPVLAVDPVEKPGEPENFQITEI 9257 Score = 186 bits (452), Expect = 8e-45 Identities = 181/713 (25%), Positives = 289/713 (40%), Gaps = 50/713 (7%) Query: 1376 TILDKPSPPG---KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 T+L + PPG KP I + S+ + W+EPE+ G S I Y +E +E + W V Sbjct: 7547 TLLIQQVPPGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLERKETTSKRWSRVTR 7606 Query: 1433 --ITKTQTSIQNLKTN----SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 + + + T S Y FR A+N + SE +E I P+ Sbjct: 7607 DPVRPMPMGVSHRVTGLIEGSQYLFRVSAINAAGVGPPSEPSE--PTFAREPIAPPSPPT 7664 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXXXXXXXXX 1541 P T+ D+E + ++ + K+ T AK Sbjct: 7665 PKVTDWTKTTADLEWIPPLKDGGSKIIGYFVEYKEEGTEAWVKAKDKEVRGTKFVITGLK 7724 Query: 1542 XXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTA 1594 ++ IA N G E + + ++ + ++ + D+ K K+ G + A Sbjct: 7725 ENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKMVIHAGGVIRILA 7784 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G PPP + W ++ + ++ TT S++ IK+ R+ YTI A N G Sbjct: 7785 YVSGQPPPVITWSRDEYPVPSEAVIE-TTSISCSMV-IKDCTRAQRGVYTITAKNDGGEV 7842 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 V ++V D P P ++ ES + W P DDGG ++ Y IEK E + W Sbjct: 7843 KKSVIVEVLDVPGPVGVPFTAENLTSESCKLNWFFPDDDGGSAISNYIIEKREAERKAWT 7902 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXX 1773 + + L Y FRV A N +G ++ IVIK ++VP Sbjct: 7903 S-CSYTAGRQNAVVNNLVLKKAYFFRVAAVNAIGVGPFNQTACEIVIKDRINVPD-RPEE 7960 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLS 1830 I + + +TW P + +GGS +I Y +E + GK K+ R L Sbjct: 7961 LEVTAITKDHISLTWKPPKNDGGSEVISYILEARTIGKDKFVRLTKDKLMERRYTYDGLR 8020 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF----VVSESTSRSVTLKW 1886 TY+FR+ A NE+G P S IT L PP+ +F VV S ++ ++ Sbjct: 8021 EGETYEFRVSAVNEVGPGKPSFSTKPITCKDELEPPTIELDFRDKVVVRVGESFALQGRY 8080 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK--DEIIFRISAEN 1944 T +P + + K +K + K ++ C+ +K + + ++ EN Sbjct: 8081 T----GKPAPSITWSRDDKELKADNHIKF---KNTLTTMCLGIVKAQRGHSGKYCVTVEN 8133 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 G + V A P PP P+ V + ++ SW P DGG+ + Y I Sbjct: 8134 CTGARKGICNVIV-----ADRPLPPEGPVVFDEVHRDHMVISWKPPLDDGGSEISNYIIE 8188 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 RDV + MW V T + L E Y++RI A N G+S+PLES+E Sbjct: 8189 KRDVNRDMWTTVTSATTKT-HCKVPKLVEGREYILRISAENMYGISDPLESEE 8240 Score = 184 bits (448), Expect = 2e-44 Identities = 192/758 (25%), Positives = 311/758 (41%), Gaps = 65/758 (8%) Query: 1349 KVENTDAGI---YKLRLENNCG--H-ADVEMNVTILDKPSPPGKP---NILEIDSSSINI 1399 +V + D G +++R EN G H ++ + +TI D SPP P I++ INI Sbjct: 5606 RVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPSPPLEVKIVDASREHINI 5665 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI---QNLKTNSSYRFRAYAV 1456 W PE G S I Y VE E +T +W+ + + + + Y R A+ Sbjct: 5666 TWKAPEKNGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAI 5725 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N + +SD SE ++ V + +PT++ ++I E +++ + +P+P + W Sbjct: 5726 NAIGVSDPSEISD--GVFAKDPDSAPTIDVATQDIVVVEGEKMDIKIPYRAIPKPSMVWK 5783 Query: 1517 RDGKKLKTAKA---TYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQ 1569 + +LKT T E NR Y N G V + V+G+ Sbjct: 5784 KGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTGTVSVTVIGLPG 5843 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTKEKTS 1628 + +E K K+ W G P ++ Y + K + + + E Sbjct: 5844 QCKDISPSELTKNSCKIS--WEPPENDGGSP---ILHYVLERREAQKKTFLPVMSGENVL 5898 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSK--PEGPVIMREIS--RESV 1683 +K+L + + ++A N G+ +E+ V + K P+ P+ + ++ S+ Sbjct: 5899 SFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSI 5958 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 T+ W P DGG +T Y IEK E D +R+ + +Y + L E EY FRV A Sbjct: 5959 TVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRA 6018 Query: 1744 QNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID-------------NESVY--IT 1787 +N G S+ S P+++ +D P + + S Y +T Sbjct: 6019 ENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLSIKKGEEIRLDAYISGSPYPTVT 6078 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGKKW-KXXXXXXXXXARIQKLSINTTY--QFRIYARNE 1844 W +++N P K EI ++ KK + + +LS T + + R+ Sbjct: 6079 WLRNDENVRQPPAKKKPEIVKKKKKTVQPEPEEEFHPPLVDRLSYEQTKKGETALMVRDA 6138 Query: 1845 IGTSLP-YTSDDKITIG--------KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 I T +T + G L P P NF E + SV W P +GGS Sbjct: 6139 IRTDHGNFTIRVENAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCTWDAPLDDGGS 6198 Query: 1896 PITNYIIEFK--TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 I NYI+E K T W VT + + + + E E IFR++AEN G P Sbjct: 6199 EIINYILEKKDNTSDDIGWV-TVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHPCY 6257 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S+ + + P P P I V S+ V SW P+ D G+P+LGY + R+V W Sbjct: 6258 SEPLVAKNQFEPPDAPNVP-RIGEVTSSTVALSWHEPK-DNGSPILGYWVERREVNSKYW 6315 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 + V ++ L + L E Y+ R+ A N G E Sbjct: 6316 IRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGE 6353 Score = 178 bits (434), Expect = 1e-42 Identities = 170/701 (24%), Positives = 288/701 (41%), Gaps = 39/701 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITK-TQT 1438 P PP + + S ++ W +P G S I+ YVVE Q + +W + K++ K Sbjct: 8950 PGPPSNIKLKDWSKSYADLVWTKPSRDGGSPILGYVVEIQRSGSAQWDKINKDLIKFCAF 9009 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP--TVEKPLKNI-TTEP 1495 + L YRFR A N+V + E TE V+ + + P TV+ +++ T Sbjct: 9010 RVPGLNEGIEYRFRIKASNKVGDGEPRELTE--TVLAKDILVPPEVTVDVACRDLLTVRA 9067 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXXXXXXXYKCI 1551 + I L G P P++TW +D + L K T N Y Sbjct: 9068 GQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDAVRADYGKYAIQ 9127 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKNG 1610 A N G+ + + +V + P +++K + D +V+ E E+ YK Sbjct: 9128 AKNSSGQAQATIIVNVLDIPGAC---QNLKVAYVTKDSCMVSWENPEDNGGTEITNYKIE 9184 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKV--YD 1664 + + + + + + + T + L ++ + + A N G T S L V + Sbjct: 9185 CRQPSQRGWTVVSSDCTKRLVKAPLVQNCEYFFRVSAENKIGAGPPTESKTPVLAVDPVE 9244 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 KP +PE I EI + V ++WK P DGG Y +EK + + W ++ Sbjct: 9245 KPGEPENFQIT-EIGKTFVFLKWKKPEYDGGSRNLAYHVEKKPKEADEWERLHKGAIKET 9303 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NES 1783 + + EN Y FRV +N G S + + +++K L P + ++ Sbjct: 9304 YFMADRCIENQIYQFRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDA 9363 Query: 1784 VYITWFPSEKNGG-SPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838 V I +E G P + + E +G + + ++ T ++ Sbjct: 9364 VSIE---AELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYI 9420 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 I A N GT +++ K+ + L P R+ VS+ + L W PE +GG I Sbjct: 9421 ITATNAAGTC---SAEAKVNV---LDRPGPIRDLKVSDISIDRCKLAWEIPEDDGGCEIY 9474 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 NYIIE K W+ I + + + + E +E IFR+ AEN +G ES+S+ Sbjct: 9475 NYIIEKCEAKRGVWS-IHSAAIITNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESII 9533 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + P P AP E+ + + ++ W +P+ DGG P+ GY + ++ W V K Sbjct: 9534 ARTQFSRPGAPDAP-EVTKITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVK 9592 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 + + L NH Y R+ A NEIG+ + + F Sbjct: 9593 SPYAGTQMTVTSLLPNHEYQFRVKAENEIGVGDASKPSRTF 9633 Score = 178 bits (433), Expect = 2e-42 Identities = 229/1033 (22%), Positives = 417/1033 (40%), Gaps = 89/1033 (8%) Query: 660 IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 I E D+ W +G+ + + E L I NV+ Q G T A+N Sbjct: 2960 ISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRF----LTIKNVQLDQAGEVTYQALNAVT 3015 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 A +L +K G+ ++ ++ + + V ++ + + W N +KA Sbjct: 3016 SA----MLNVKEGDAFFSVKLQDYTAV---EKDEVTFDCELSRDV--PVKWFHNEIEIKA 3066 Query: 778 LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + IL KKV KD+GVY G +TS+ + +E + +P Sbjct: 3067 SKMVTIKVEGKRRILNLKKVENKDKGVYVCDC----GTDKTSSNLNIEARDIKVVKPIYG 3122 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 + F + T + ++ + V W +++S S + DG L + N Sbjct: 3123 VELF------DGETARFEVEISEDDVHG-QWKLKGDVLSASPDVEIIEDGAKHTLTLYNC 3175 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ--KSYETEEGKTVILECQTS 953 SG+ +N+ K S A + + ++FV L + YE +E + I + + Sbjct: 3176 RVS-QSGEVTFQGANA--KCS--ANLKVKELPISFVMPLSDVQVYEKDEARFEIELSREA 3230 Query: 954 HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 TV +W +E+ + EI+ EG+ D +D+ TS LV++ Sbjct: 3231 KTV--RWLKGSQELKVDEKFEILAEGKRHILVVKSVAYEDEAKYMFEAEDKRTSAKLVIQ 3288 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 EF+R ++D VKE++ A +E++ E V W ++ + P K + + G I Sbjct: 3289 GIRLEFVRPIKDVTVKERETAEFSIELSHEKIQVTWYKNDVRLHPSKVVH-MSEHGKIHT 3347 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133 L + S+ D ++ A +TV+E P T+LQ+ + ++ E++K Sbjct: 3348 LSFKEVSIDDTSLIKVEALGKTSEAMLTVLEGEPYFTTKLQDYTAVEKDEVVLMCEVSKS 3407 Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 A V+WFKD +EI S ++ + DGKK+ L + + + GEY C+ G+ K A L +EE Sbjct: 3408 SAQVKWFKDTNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIEE 3467 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 I + L + T + T EI +E + W K + + + + K L Sbjct: 3468 RDIKISRPLYSVEVTETETARFET-EISEEDVHGHWKLKGDALHQSPDCEIKEEGTKHML 3526 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDY 1311 I+ D +AKST +L+V+ ++ R+ + G T + Y Sbjct: 3527 ILYNVRMDMAGAVDFSAANAKSTAQLRVKARTI--GLLRPLRDVTVTAGETATFDCELSY 3584 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 + P EW V S ++ + + SLT++ V T+AG KL ++ A Sbjct: 3585 EDIPV---EWFVGSTKMEPSDRVVTRAEGRLHSLTLRDVIMTEAGEVKLTAKDFVTQA-- 3639 Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 +T+ + P KP ++ ++ E E T I+ + ++ D + + Sbjct: 3640 --KLTVNEPPVEFSKP----LEDQTV-----EEEAT---AILECELSREKADVKWFRDGQ 3685 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT---EYYKVIKETKIQSPTVE--K 1486 I KT+ + + R R + + + D+ T + +K ++ P VE K Sbjct: 3686 EIRKTKKH----EMVAEGRIRRLIIKDCSLDDSKTYTCDAKEFKTSAFLNVEPPFVEFSK 3741 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546 PL ++ + E + C KV W++DG +++ K YE Sbjct: 3742 PLHDVEVKEKESAKFECEVSR-ESAKVRWFKDGAEIRKGK-KYE-----IIAKGLQRILI 3794 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI-----P 1600 K + F+D E E + ++T+ E+ + K+ E T I+ + P Sbjct: 3795 ISKAV-FDDEAEYECDARTS-KSSGMLTVVEEEARFTKNLANVEGTETDSIKMVCEVSKP 3852 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--TIEASNTAGTSSV-E 1657 EV W+K ++ Y K ++ I++L+ + +Y + AS T GT + E Sbjct: 3853 SAEVTWHKGDQEIPEGGRYEHVADGKKRILIIQDLRMDDAGEYHCKLPASETTGTLKISE 3912 Query: 1658 VTLKVYDKPSKPE 1670 + + +P E Sbjct: 3913 LAAEFIARPQNQE 3925 Score = 175 bits (427), Expect = 8e-42 Identities = 115/401 (28%), Positives = 183/401 (45%), Gaps = 18/401 (4%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + V A++ G P P W + N + + + + V+ IK++ R S +Y+ Sbjct: 10005 KAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYS 10064 Query: 1645 IEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 + A N++G +E TLK+ D P PE P + +I ++ T+ W P +DGG +T Y Sbjct: 10065 LVAENSSG--KIEQTLKIIIRDIPGPPEPPFEISDIDSDACTLSWNKPTEDGGSNITNYV 10122 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761 +EK + W V + + C I KL EY+FRV A+N G S+ L SE +V K Sbjct: 10123 VEKCDVSRGDW--VTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISDPLASERMVAK 10180 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX 1820 DVP ++ + +++ W E +GGSP+ Y +E K+ W Sbjct: 10181 FPFDVPG-EPLNCRINKVNKDCMFVAWDKPESDGGSPVTGYYIERKERNSLLWVKANDSV 10239 Query: 1821 XXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + Y FR+ A N G P D IT + P +P V + T Sbjct: 10240 VRTTEYPCAGLIEGLEYTFRVSAINRAGQGKPSKKTDFITARTPVDAPGKPE---VLDVT 10296 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHCIENIKEKDEI 1936 +V+L WT+P+++GGS I Y +E + G +W + T +V E+ ++E Sbjct: 10297 KNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSSQNVPREEYTATGLEEGANY 10356 Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 FR+ A+ V +S P+E L V PP L ++M Sbjct: 10357 QFRVIAKTAVNISRPSEITDPILVSAENV--PPRIELSVQM 10395 Score = 174 bits (423), Expect = 3e-41 Identities = 168/718 (23%), Positives = 288/718 (40%), Gaps = 58/718 (8%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G + + + Y+A P+P+ W +K + + L + K ++ DAG+Y Sbjct: 5760 VVEGEKMDIKIPYRAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVY 5819 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + LEN+ G ++VT++ P + E+ +S I W+ PEN G S I++YV+E Sbjct: 5820 TVTLENSLGSVTGTVSVTVIGLPGQCKDISPSELTKNSCKISWEPPENDGGSPILHYVLE 5879 Query: 1419 YQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E ++ V + + +++L NS Y FR AVN++ + E + ++ Sbjct: 5880 RREAQKKTFLPVMSGENVLSFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQK 5939 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTWY------RDGKKLKTAKATYE 1530 + P +E N T+ + + GG P +T Y +DG + + Sbjct: 5940 QHPDPPIEVAGLNPTSNSITVTWMAPPYDGGCP---ITGYIIEKIEKDGDRFERCVPNLV 5996 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQ--QKPVITI-SNEDIKQK 1583 ++ A N G + T ++ P +T+ + Sbjct: 5997 PGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLS 6056 Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN---DKEYNITTKEKTSV----------- 1629 K G+E + A I G P P V W +N + K+ I K+K +V Sbjct: 6057 IKKGEEIRLDAYISGSPYPTVTWLRNDENVRQPPAKKKPEIVKKKKKTVQPEPEEEFHPP 6116 Query: 1630 ----IRIKELKRSHSSKYTIEASNT-AGTSSVEV-----------TLKVYDKPSKPEGPV 1673 + ++ K+ ++ +A T G ++ V + V DKP P Sbjct: 6117 LVDRLSYEQTKKGETALMVRDAIRTDHGNFTIRVENAHGFATASCDVNVLDKPGPPVN-F 6175 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVADVDRDVETYCIQKL 1731 EI SV W PLDDGG E+ Y +EK + D+ W+ V + Y + KL Sbjct: 6176 GFDEIRNTSVVCTWDAPLDDGGSEIINYILEKKDNTSDDIGWVTVTSTHKGY-NYPVTKL 6234 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 E EY+FRV A+N G SEP+V K + P + + +V ++W Sbjct: 6235 IEGKEYIFRVTAENKFGCGHPCYSEPLVAKNQFE-PPDAPNVPRIGEVTSSTVALSWH-E 6292 Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTS 1848 K+ GSPI+ Y VE ++ K+ A +++ L Y FR+ A N G Sbjct: 6293 PKDNGSPILGYWVERREVNSKYWIRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPG 6352 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 D + PP P +V + T+ ++ + W P NGG I Y +E V Sbjct: 6353 EFSVPTDPQAAMDPILPPGPPVPKIV-DVTNTTIDISWQPPLYNGGGEILGYHVERCLVG 6411 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 K W + ++ + + E + R+ A N G P ++ V+ ++ P Sbjct: 6412 EKDWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEPEEAP 6469 Score = 171 bits (417), Expect = 1e-40 Identities = 216/903 (23%), Positives = 355/903 (39%), Gaps = 56/903 (6%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 E P + F + + +++ A L + + + K D E + +++K Sbjct: 6467 EAPGVEFDISVRNGVIIRAGETLRLPAVVTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSS 6526 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 TL I+K D Y + T +KV+V++ P +VD + K+ +T Sbjct: 6527 TLSIKKALRTDHGIYQITGTNPSGTKSVSVKVDVMDVPGPVVDLKTVNVSKKMISLTWSD 6586 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG-H 1368 ++V K K + +P ++ + I + + + ++++ N G Sbjct: 6587 PLDNGGSDIMGYVVERKDAKMHIYRQP-LEVAACKCDIVGLLDGEEYMFRVVARNKFGLG 6645 Query: 1369 ADVEMN-VTILDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 A VE+ V +D PS P K E ++I + W+ P + G S II Y +E D+ Sbjct: 6646 APVELGPVLAVDPKGVPSAPEKLRYTERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDS 6705 Query: 1425 TEW-ISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 E+ ++ +N+ K T +++NL N + FR AVNEV + S+ I+E + SP Sbjct: 6706 NEYDVANRNLCKDLTITLENLTENMMFDFRVKAVNEVGNGEPSKAISVN--IQEDE-NSP 6762 Query: 1483 TVE--KPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE----NR 1532 TV+ K K+ I IE+ G+P P W ++G + T T E NR Sbjct: 6763 TVKWMKFFKSDAIIVRKGAAIEIPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINR 6822 Query: 1533 XXXXXX----XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV--ITISNEDIKQKHKV 1586 YK A N G + + V I +P+ I DIK + Sbjct: 6823 QTITTKIGIPESVRQDTGMYKLTATNTRGVGQRTMRVDILDRPLPPRNIVVSDIKAE-SC 6881 Query: 1587 GDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 W G ++ ++ +K ++D + +T + +L+ + ++ I Sbjct: 6882 YLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWD-QLTCCIMDRRYGVYKLEAYGTYQFQI 6940 Query: 1646 EASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 +A N G S S +V LK + P P+ P I+ +R S+ + W+PP D+GG + Sbjct: 6941 KAENKYGISDGCESEKVVLKDPFGLPGPPQRPRIISH-TRSSMVVTWEPPKDNGGSTIQG 6999 Query: 1701 YAIEKHEPDNNRWIKV--ADVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 Y +EK E W +V A V + Y + L E EY FRV+AQN G E+ Sbjct: 7000 YWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEA 7059 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814 V P SV ++W P +++GGSPI Y VE++ EG +WK Sbjct: 7060 TECVFALDPRNPPSQPPAPVVTDKSPSSVSLSWTPPDRDGGSPIKGYIVEVQDEGSHEWK 7119 Query: 1815 XXXX----XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 + L N +FRI A N G S P I + L P Sbjct: 7120 RINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPSPRTSDIIVQDILEEPVITI 7179 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV---KGKSWTKIVTVGGSVHEHCI 1927 + E + P + G P+ N EF + K+ + V + Sbjct: 7180 DVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTAPSEKKNERHTLPVDSDISSSDT 7239 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMT 1985 ++ E S + + ++ V++ V P AP +I + + Sbjct: 7240 TSVVTIPESKLHHSGRYIITANNQAGTKIVKV--RVNVLDLPGAPKDITISDITRGTCRL 7297 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 SW P+ DGG + Y I + V W +V T + DL E Y+ RI A N Sbjct: 7298 SWKPPDCDGGDRIKSYFIEKKTVEGKAWTKVNPA-CTTQSLVVPDLIEGQEYLFRIRAEN 7356 Query: 2046 EIG 2048 G Sbjct: 7357 RFG 7359 Score = 171 bits (415), Expect = 2e-40 Identities = 187/877 (21%), Positives = 373/877 (42%), Gaps = 46/877 (5%) Query: 830 AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886 A P F+ Q+I ++E +I V +P +IT W ++ I S DG+ Sbjct: 2655 AVPLKFVKELQDIVLQEAESIGSSAVFECQISPSTAITTWMKDGSNIRESPKHKFTSDGK 2714 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 + +L I +V D+G+Y CVA + + A++ ++ V F K+L++ +G+ + Sbjct: 2715 DRKLQIIDVQLS-DTGEYTCVAKLGNKEKTSTAKLVVEELPVKFTKNLEEETSVLKGQPM 2773 Query: 947 ILECQTSHTVSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 L C+ S W N KE+ + + +I G D GV C ++ + Sbjct: 2774 YLTCELSKDKDVVWKKNGKELKEIPGKIQINIIGLQRAVTIQDMNDDDAGVYTCECENIK 2833 Query: 1006 TSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWER-DGEIIKPKKNKY 1063 T T + V E + +++ K L+D VK K A + E+ ET + W + + EI +K Sbjct: 2834 TETNVKVIEIVRDWLVKPLRDQHVKPKSTATFKGELFKETPNWKWYKGNDEIPNEPTDKT 2893 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 + +K G L I+N D EY+ + A++T+ E EI+ L + +V + + Sbjct: 2894 EVKKEGKEITLTIKNAQPDDVAEYAVEVEGRRYAAKLTLGEREAEILKPLASVEVVEKTE 2953 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 A FE E+++ D W G + S + +G K+ L I + LD AGE + + N+ Sbjct: 2954 ANFETEISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRFLTIKNVQLDQAGEVTYQALNA 3013 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 +A+L V+E F+++L ++ V + D L+ ++P V W+ + I+ ++ Sbjct: 3014 VTSAMLNVKEGDAFFSVKLQDYTAVEKDEVTFDCELSRDVP-----VKWFHNEIEIKASK 3068 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300 T+ + K+R L ++K D+ Y C K+++ L +E + K+V + Sbjct: 3069 MVTIKVEGKRRILNLKKVENKDKGVYVCDCGTDKTSSNLNIEARDI--KVVKPIYGVELF 3126 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 G V+ + +W + ++ + D +LT+ + +G Sbjct: 3127 DGETARFEVEISE-DDVHGQWKLKGDVLSASPDVEIIEDGAKHTLTLYNCRVSQSGEVTF 3185 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + N A++++ + P + E D + I E + + + ++ Q Sbjct: 3186 QGANAKCSANLKVKELPISFVMPLSDVQVYEKDEARFEI-----ELSREAKTVRWLKGSQ 3240 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 E+ E + + + + I +K + +Y A + E + + T VI+ +++ Sbjct: 3241 ELKVDEKFEI--LAEGKRHILVVK-SVAYEDEAKYMFEAE----DKRTSAKLVIQGIRLE 3293 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXX 1539 +P+K++T + E E + I + +VTWY++ +L +K + Sbjct: 3294 ---FVRPIKDVTVKERETAEFS-IELSHEKIQVTWYKNDVRLHPSKVVHMSEHGKIHTLS 3349 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 I G+ + + ++ +P T +D K DE ++ + Sbjct: 3350 FKEVSIDDTSLIKVEALGKTSEAMLTVLEGEPYFTTKLQDYTAVEK--DEVVLMCEVSK- 3406 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE--ASNTAGTSSVE 1657 +V W+K+ N++ K I K ++ +K+ ++ + +Y + + TA ++E Sbjct: 3407 SSAQVKWFKDTNEITPSKNVLIKADGKKRILTVKKAEKGNIGEYVCDCGSDKTAAKLNIE 3466 Query: 1658 -----VTLKVYD-KPSKPEGPVIMREISRESVTIEWK 1688 ++ +Y + ++ E EIS E V WK Sbjct: 3467 ERDIKISRPLYSVEVTETETARFETEISEEDVHGHWK 3503 Score = 168 bits (408), Expect = 2e-39 Identities = 175/769 (22%), Positives = 322/769 (41%), Gaps = 45/769 (5%) Query: 1312 QAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 + F D+WI ++K+ IK + +K EN AG K +E D Sbjct: 5282 ERFDPETDKWIKSNKLPIKDTTFRVKGLPTKKKYKFRVLAENL-AGQGKPSVET-----D 5335 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + +D P PGKP + +I +S ++ W PE+ G + I Y++E Q+ T EW+ V Sbjct: 5336 PVLIKDPIDPPWAPGKPFVKDIAKTSADLQWTRPEHDGGAKIESYIIELQKTGTEEWVRV 5395 Query: 1431 -KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 +++ T+ S++ L Y FR A+N S+ S+ ++ V+ + ++ P + L+ Sbjct: 5396 AEDVPTTEHSLKGLMEKQEYSFRVKAINVAGESEPSDPSD--PVVCKERLYVPNPPRWLE 5453 Query: 1490 NIT-TEPNEDIELT--CIFGGVPQPK-VTWYRDGKKLK------TAKATYENRXXXXXXX 1539 + T+ N D++ T GG P V RD ++ T K T Sbjct: 5454 VVNITKINCDLKWTEPDSDGGSPITNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGS 5513 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 + ++ E+E S + P ++ ++ ++H V +W Sbjct: 5514 LYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYALTVVEVSKRH-VDLKWEPPNSD 5572 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--- 1653 G P + + K K+ + T S R+ ++ ++ + A N AG Sbjct: 5573 GGRPITKYVIEKK-EKVGTRWVKSGKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHP 5631 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 S V + + D S P P+ ++ + SRE + I WK P +GG +T Y +E E + Sbjct: 5632 SEPTVIMTIEDAISPPSPPLEVKIVDASREHINITWKAPEKNGGSPITGYHVELSEAETE 5691 Query: 1712 RWIKVADVD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSX 1769 +W+++ +++ + + +Y+ RV A N +G S+ E S+ + K P+ Sbjct: 5692 KWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTI 5751 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQ 1827 ++ E + I P ++ K E+K E + + Sbjct: 5752 DVATQDIVVVEGEKMDIK-IPYRAIPKPSMVWKKGDTELKTEDRL-TLTCELNRVHLELL 5809 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 K + + N +G+ T +T+ + P Q ++ SE T S + W Sbjct: 5810 KCKHEDAGVYTVTLENSLGS---VTGTVSVTV---IGLPGQCKDISPSELTKNSCKISWE 5863 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 PE++GGSPI +Y++E + + K++ +++ G +V ++++ E FR+ A N +G Sbjct: 5864 PPENDGGSPILHYVLERREAQKKTFLPVMS-GENVLSFVVKDLMLNSEYHFRVKAVNKIG 5922 Query: 1948 VSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 E ++ V +E+ P PP + ++I +T W P +DGG P+ GY I Sbjct: 5923 SGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSITVT-WMAPPYDGGCPITGYIIEKI 5981 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + + V + + L+E Y R+ A N G S+P S Sbjct: 5982 EKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRAENIAGASDPSRS 6030 Score = 167 bits (406), Expect = 3e-39 Identities = 191/825 (23%), Positives = 318/825 (38%), Gaps = 66/825 (8%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283 ++TW K V+ ++ + ++ L+I+ D +Y ++ + + V V Sbjct: 9084 EITWTKDARVLGRDKRTEMNNNFPLVELVIQDAVRADYGKYAIQAKNSSGQAQATIIVNV 9143 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH------TKPS 1337 ++ P + + Y K + +V ++ I N KI +C+ T S Sbjct: 9144 LDIPGACQNLKVAYVTKD----SCMVSWENPEDNGGTEITNYKI--ECRQPSQRGWTVVS 9197 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPN---ILE 1391 D + V+N + +++ EN G + + V +D PG+P I E Sbjct: 9198 SDCTKRLVKAPLVQNCEY-FFRVSAENKIGAGPPTESKTPVLAVDPVEKPGEPENFQITE 9256 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSY 1449 I + + + W +PE G S + Y VE + + EW + I +T N Y Sbjct: 9257 IGKTFVFLKWKKPEYDGGSRNLAYHVEKKPKEADEWERLHKGAIKETYFMADRCIENQIY 9316 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 +FR NE S+ T E ++KE +Q K + + + + + + G P Sbjct: 9317 QFRVQTKNEGGESNWVTTAEV--LVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKP 9374 Query: 1510 QPKVTWYRDG------KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 QP+V W ++G K L+ T N Y A N G Sbjct: 9375 QPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEA 9434 Query: 1564 VVGIQQKP--VITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 V + +P + + DI + K+ W + G I K K ++ Sbjct: 9435 KVNVLDRPGPIRDLKVSDISIDRCKLA--WEIPEDDGGCEIYNYIIEKCEAKRGVWSIHS 9492 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVE----VTLKVYDKPSKPEGPVIM 1675 T+ ++ L + + + A N G +VE + + +P P+ P + Sbjct: 9493 AAII--TNSAKVTRLIEGNEYIFRVRAENKMGAGPAVESESIIARTQFSRPGAPDAPEVT 9550 Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 + I+++++ + W P +DGG +T Y +EK E RW V + L N Sbjct: 9551 K-ITKDTMVVMWCSPDNDGGKPITGYILEKKEEHAIRWAPVVKSPYAGTQMTVTSLLPNH 9609 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEK 1793 EY FRV A+N +G +A S+P TA D P S+ + W Sbjct: 9610 EYQFRVKAENEIGVGDA--SKPSRTFTARDPVEPPGPVSNLKVTDSSKTSITLAWTKPTY 9667 Query: 1794 NGGSPIIDYKVEI--KQEGKK----WK---XXXXXXXXXARIQKLSINTTYQFRI----Y 1840 +GG+P+I Y VEI K GKK WK + L Y+FR+ Sbjct: 9668 DGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFRVTRDDS 9727 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 + + S P K L P V++ T S L W+ PE++GGS +T+Y Sbjct: 9728 GKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTDMTMSSCNLTWSPPETDGGSNVTHY 9787 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 I+E + + K+W TV +V + I N+ E FR+ A N G +P + Sbjct: 9788 IVEKREIDRKTW---ATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVTPKSY 9844 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 L P +++ + N W P DGGA + GY I Sbjct: 9845 LASDPVSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVI 9889 Score = 165 bits (401), Expect = 1e-38 Identities = 175/783 (22%), Positives = 305/783 (38%), Gaps = 48/783 (6%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E +PP F KK + G+ + EC + P W G EI + + + Sbjct: 220 EEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRII----SR 275 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S L++ + K G Y+ A N+ G + L I EP + + L ++ + Sbjct: 276 QTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA--SEPARFLRKLSNISIPMS 333 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLK 806 + + L + G+ + +TW K+ K + A + T + L+ + D G+Y+ + Sbjct: 334 QKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGIYSCE 393 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N+ G A +T EP F+ + ++++ ++L T P +TW Sbjct: 394 VSNAFGREICHATVTAV------TEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTW 447 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 Y++ + + S + L + + +G Y C SN G A+V E Sbjct: 448 YKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTE 507 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRXXX 983 FVK L + + LEC + + WY + K++ + + + Sbjct: 508 PARFVKKL-TDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCIL 566 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAI---LEVE 1039 G C V + + + I F + + ++K+K VA+ L++E Sbjct: 567 ECLHECNDATPGKYSCEVSNSIGTD--ICHANITTFTEPARFELKLKDKQVAMSKNLKLE 624 Query: 1040 INSETAD---VVWERDGEIIKPKKNKYDFEKRGHIRKL-YIRNTSVHDEGEYSCILRD-- 1093 A V W +DG+ + +Y+ G+ L + + G+YSC + + Sbjct: 625 CTFTGAPKIFVTWYKDGKQLY-ASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSY 683 Query: 1094 --ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSN 1150 + C AEVT P + L +Q + +G K E G V W+KDG + S Sbjct: 684 GKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASY 743 Query: 1151 HIQLTIDGKKQKLK-IYDCDLDDAGEYSCEV----GNSKCTAILTV-EEPSI--NFTLRL 1202 + G L+ +++CD + G+YSCEV G+ C A++T+ E I FT + Sbjct: 744 RCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKP 803 Query: 1203 PEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 E I L + + L V WYK I ++ + + + +RK T Sbjct: 804 SEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVT 863 Query: 1262 DQCEYTCVLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 D YTC + T +V V + PP + + G + L P Sbjct: 864 DSGVYTCSASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPV 923 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 +W+ + + + TK + +A+L I + TDAG Y + NN G + VTI Sbjct: 924 KIQWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTI 983 Query: 1378 LDK 1380 DK Sbjct: 984 KDK 986 Score = 163 bits (396), Expect = 5e-38 Identities = 182/744 (24%), Positives = 307/744 (41%), Gaps = 69/744 (9%) Query: 1179 EVGNSKCTAILTV--EEPSINFTLRLPEFILVPAN-TDAYLTVEIPDETLDVT-----WY 1230 EVGN + + ++V +E + T++ +F A +EIP E + + W Sbjct: 6741 EVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIEIPAEIVGLPLPTFEWT 6800 Query: 1231 KKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 K VI+ TE TL S+ R I K + + +T V Sbjct: 6801 KNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGMYKLTATNTRGVGQRTMRVD 6860 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTI 1347 I+D R SD+ Y + P D + + I++K +K D + I Sbjct: 6861 ILDRPLPPRNIVVSDIKAESCYLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWDQLTCCI 6920 Query: 1348 K-------KVENTDAGIYKLRLENNCGHAD-VEMNVTILDKP----SPPGKPNILEIDSS 1395 K+E ++++ EN G +D E +L P PP +P I+ S Sbjct: 6921 MDRRYGVYKLEAYGTYQFQIKAENKYGISDGCESEKVVLKDPFGLPGPPQRPRIISHTRS 6980 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN-------SS 1448 S+ + W+ P++ G STI Y +E +E W V T+ +++ L+ N + Sbjct: 6981 SMVVTWEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAE 7040 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI---- 1504 Y+FR A N + SE TE + ++P + P +T + + L+ Sbjct: 7041 YKFRVMAQNAAGVGPPSEATECVFALDP---RNPPSQPPAPVVTDKSPSSVSLSWTPPDR 7097 Query: 1505 FGGVP-QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC----IAFNDHGEV 1559 GG P + + +D + + ++ KC +A N GE Sbjct: 7098 DGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGES 7157 Query: 1560 ETS------CVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNG-- 1610 E S V I ++PVITI + + + G + A I G P P V W +G Sbjct: 7158 EPSPRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTA 7217 Query: 1611 -NKLENDK-----EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 ++ +N++ + +I++ + TSV+ I E K HS +Y I A+N AGT V+V + V D Sbjct: 7218 PSEKKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIVKVRVNVLD 7277 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 P P+ + + +I+R + + WKPP DGG + Y IEK + W KV + + Sbjct: 7278 LPGAPK-DITISDITRGTCRLSWKPPDCDGGDRIKSYFIEKKTVEGKAWTKV-NPACTTQ 7335 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + + L E EY+FR+ A+N G+ E + + P + Sbjct: 7336 SLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKARDPIH-PPDPPTRVKIIDVSKGI 7394 Query: 1784 VYITWFPSEKNGGSPIIDYKVE--------IKQEGKKWKXXXXXXXXXARIQKLSINTTY 1835 V +TW P + +GG+P+ Y +E +QE + +++ L Y Sbjct: 7395 VTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQCNRRDIDTTTFKVEDLHEGAEY 7454 Query: 1836 QFRIYARNEIGTSLPYTSDDKITI 1859 +FR+ A NE+G S P ++ I + Sbjct: 7455 EFRVKAVNEVGASRPSSTAGPIIV 7478 Score = 161 bits (391), Expect = 2e-37 Identities = 164/679 (24%), Positives = 296/679 (43%), Gaps = 46/679 (6%) Query: 695 LKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751 L+I +V+ G YT VA N+E ++ +V+ E+ P + + L+ V +G+ Sbjct: 2718 LQIIDVQLSDTGEYTCVAKLGNKEKTSTAKLVV-----EELPVKFTKNLEEETSVLKGQP 2772 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLKA 807 + L+ ++ + + W KN K +K +P K G ++TI + D GVYT + Sbjct: 2773 MYLTCEL--SKDKDVVWKKNGKELKEIPGKIQINIIGLQRAVTI-QDMNDDDAGVYTCEC 2829 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 EN +T + V E + PL ++ VK K T + + P+ WY Sbjct: 2830 EN----IKTETNVKVIEIVRDWLVKPL-----RDQHVKPKSTATFKGELFKE-TPNWKWY 2879 Query: 868 RNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 + N+ I P++ +G+ I L I N + D +Y A G+ + A++T+ Sbjct: 2880 KGNDEIPNEPTDKTEVKKEGKEITLTIKNAQPD-DVAEY---AVEVEGR-RYAAKLTLGE 2934 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 + +K L S E E E + S V +W + ++ +I EG Sbjct: 2935 REAEILKPL-ASVEVVEKTEANFETEISEDDVPGEWKLQGQVLTRSPTCDIRSEGTKRFL 2993 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 G + + TS ML VKE F KLQD+ EKD + E+ S Sbjct: 2994 TIKNVQLDQAGEVTYQALNAVTSAMLNVKEGDAFFSVKLQDYTAVEKDEVTFDCEL-SRD 3052 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W + IK K + G R L ++ D+G Y C + ++ + + Sbjct: 3053 VPVKWFHNEIEIKASK-MVTIKVEGKRRILNLKKVENKDKGVYVCDCGTDKTSSNLNIEA 3111 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 +++ + ++ G A FE+E+++ D +W G + S +++ DG K L Sbjct: 3112 RDIKVVKPIYGVELFDGETARFEVEISEDDVHGQWKLKGDVLSASPDVEIIEDGAKHTLT 3171 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 +Y+C + +GE + + N+KC+A L V+E I+F + L + + V +A +E+ E Sbjct: 3172 LYNCRVSQSGEVTFQGANAKCSANLKVKELPISFVMPLSD-VQVYEKDEARFEIELSREA 3230 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 V W K ++ EKF ++++ K+ L+++ +D+ +Y D +++ KL ++ + Sbjct: 3231 KTVRWLKGSQELKVDEKFEILAEGKRHILVVKSVAYEDEAKYMFEAEDKRTSAKLVIQGI 3290 Query: 1285 --EFPPKIVDYEREYRIKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 EF I D + R + L + Q ND + SK++ +H K Sbjct: 3291 RLEFVRPIKDVTVKERETAEFSIELSHEKIQVTWYKNDVRLHPSKVVHMSEH------GK 3344 Query: 1342 SASLTIKKVENTDAGIYKL 1360 +L+ K+V D + K+ Sbjct: 3345 IHTLSFKEVSIDDTSLIKV 3363 Score = 161 bits (391), Expect = 2e-37 Identities = 183/758 (24%), Positives = 305/758 (40%), Gaps = 52/758 (6%) Query: 1338 IDSKSASLTIKKVENTDAG---IYKLRLENNCGHADVEMNV---TILDKPSPPGKP--NI 1389 ++S S KVE G ++++ EN G + + +D PPG P I Sbjct: 6318 VNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGEFSVPTDPQAAMDPILPPGPPVPKI 6377 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNS 1447 +++ +++I+I W P G I+ Y VE + +W+ + ++ L + Sbjct: 6378 VDVTNTTIDISWQPPLYNGGGEILGYHVERCLVGEKDWVRCTEFRCKDRKYTVTGLTEGA 6437 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK---NITTEPNEDIELTCI 1504 Y R YAVNE A TE + KE + ++P VE + + E + L + Sbjct: 6438 DYNLRVYAVNEGG-HGAPGMTEPVQA-KEPE-EAPGVEFDISVRNGVIIRAGETLRLPAV 6494 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVET 1561 G P P+V W +DG + E Y+ N G Sbjct: 6495 VTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPSGTKSV 6554 Query: 1562 SCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 S V + P V+ + ++ +K + W G +++ Y K Y Sbjct: 6555 SVKVDVMDVPGPVVDLKTVNVSKK-MISLTWSDPLDNGG---SDIMGYVVERKDAKMHIY 6610 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEV-TLKVYDKPSKPEGPVIMR- 1676 + I L + + A N G + VE+ + D P P +R Sbjct: 6611 RQPLEVAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDPKGVPSAPEKLRY 6670 Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNEN 1734 E ++ ++T+ W+ P DGG + Y IEK D+N + + ++ +D+ T ++ L EN Sbjct: 6671 TERTKNTITLTWEAPRSDGGSPIIGYYIEKMRQDSNEYDVANRNLCKDL-TITLENLTEN 6729 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX--XXXXXXXXIDNESVYITWFPSE 1792 + FRV A N VG E ++ + I+ + P+ I + I P+E Sbjct: 6730 MMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIE-IPAE 6788 Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 G P+ ++ K + I + +I T R + G T Sbjct: 6789 IVG-LPLPTFEWT-KNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGM-YKLT 6845 Query: 1853 SDDKITIGKT------LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 + + +G+ L P PRN VVS+ + S L W PE NGGS +TNYI+E + Sbjct: 6846 ATNTRGVGQRTMRVDILDRPLPPRNIVVSDIKAESCYLTWDAPEDNGGSDLTNYIVEKRD 6905 Query: 1907 VKGKS--WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 K W ++ T + + ++ F+I AEN G+S ES+ V L+ Sbjct: 6906 ASKKKSDWDQL-TCCIMDRRYGVYKLEAYGTYQFQIKAENKYGISDGCESEKVVLKDPFG 6964 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT- 2023 +P PP P I S++V+T W P+ +GG+ + GY + R+ W V + V Sbjct: 6965 LPGPPQRPRIISHTRSSMVVT-WEPPKDNGGSTIQGYWLEKRERGAVYWSRVNRAPVTKP 7023 Query: 2024 ----LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 L++N+ L E Y R+ A+N G+ P E+ E Sbjct: 7024 AVKGLEYNVLHLIEGAEYKFRVMAQNAAGVGPPSEATE 7061 Score = 156 bits (378), Expect = 7e-36 Identities = 120/446 (26%), Positives = 200/446 (44%), Gaps = 35/446 (7%) Query: 1642 KYTIEASNTAGTSSV-EVTLKVY-----DKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 K+ + A N AG E T V+ + PS+P PV+ + S SV++ W PP DGG Sbjct: 7042 KFRVMAQNAAGVGPPSEATECVFALDPRNPPSQPPAPVVTDK-SPSSVSLSWTPPDRDGG 7100 Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIAQNPVGFSE-A 1752 + Y +E + ++ W ++ D+ + T Y + L EN + FR++A N G SE + Sbjct: 7101 SPIKGYIVEVQDEGSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEPS 7160 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKVEIKQEGK 1811 + I+++ L+ P ++ + P+ +G P + ++ + + Sbjct: 7161 PRTSDIIVQDILEEPVITIDVTSQELLNCRAGTTLKIPATISGKPLPNVTWEFDGTAPSE 7220 Query: 1812 KWKX----------XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 K I + ++ + ++ I A N+ GT + K+ + Sbjct: 7221 KKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKIV-----KVRVN- 7274 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 L P P++ +S+ T + L W P+ +GG I +Y IE KTV+GK+WTK V + Sbjct: 7275 VLDLPGAPKDITISDITRGTCRLSWKPPDCDGGDRIKSYFIEKKTVEGKAWTK-VNPACT 7333 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVGS 1980 + ++ E E +FRI AEN G T + + + P PPT ++I V Sbjct: 7334 TQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKARDPIHPPDPPTR-VKIIDVSK 7392 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIA-----IRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 IV +W P+ DGGAP+ YNI + W + + D++T F + DL E Sbjct: 7393 GIVTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQCNRRDIDTTTFKVEDLHEGA 7452 Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKV 2061 Y R+ A NE+G S P + P V Sbjct: 7453 EYEFRVKAVNEVGASRPSSTAGPIIV 7478 Score = 150 bits (364), Expect = 4e-34 Identities = 161/598 (26%), Positives = 264/598 (44%), Gaps = 80/598 (13%) Query: 632 IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 IPPTF+KKP D EG + LE R+ + W +EI + V+ +S++ + Sbjct: 795 IPPTFTKKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAV 854 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 C L+ V G YT A N G AS +V+ I T +K PP PLK M V +GE Sbjct: 855 MC--LRKATVT--DSGVYTCSASNEAGTASFQVVVNI-TEQKRPPTFDIPLKPMTVSEGE 909 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV-KALPTKS---DGDTHSITILKPKKVKDEGVYTLK 806 + LS V G+P I W K+ + V + TK DG T ++ I + K D G Y K Sbjct: 910 RLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTFVDG-TATLEINQASKT-DAGDYLCK 967 Query: 807 AENSEGIAETSAVITVEE------------PTEENAEPPL----FINRFQEITVKEKGTI 850 A N+ G + +T+++ PT A L FI + I + EKGT Sbjct: 968 ATNNAGSEFSKTKVTIKDKAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTA 1027 Query: 851 KLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 +A+V +P+P++ W + ++ I G+ +L I V ++ DSG Y+CVAS Sbjct: 1028 TFIAKVGGDPIPNVKWMKGKWRQMTHGGRINIQQKGQESKLEIKEV-TKSDSGQYRCVAS 1086 Query: 910 NSAGKSSHGARVTIDVEK------VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHN 963 N G+ + +D +K V K K +E K + + + V K Y Sbjct: 1087 NKHGEIECSTDLNVDEKKESGPEVVKLKKTPSKQKSPKEDKDIDI-VELLRNVDPKEYEK 1145 Query: 964 KKEISGM-DHREIIQ-----EGRXXXXXXXXXXXXDVG-VIKCIVKDQETSTMLVVKETI 1016 + G+ D R ++Q + D+ ++ + + E S + + + I Sbjct: 1146 YARMYGITDFRGLLQAIEFLKKEKGEESGRPEEDEDLAKLVSDLQRRMENSEPVTLLKDI 1205 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 + Q ++ ++ V E+++N + W +D + ++ +KYD + G + L I Sbjct: 1206 TD-----QTTQLNKEAVFECEIKVNYPEITLAWYKDTQKLE-TNDKYDIKLVGDRQILKI 1259 Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136 +N+ D+ +++ R+QN VN+ ATFE EL+ +A+ Sbjct: 1260 KNS---DQIQFT----------------------KRIQNIVVNERQSATFECELSFDNAV 1294 Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-----EVGNSKCTAIL 1189 V W+KD E++ S +G++ + I + DD G YS VG +K TA L Sbjct: 1295 VTWYKDAWELKESLKYTFKCEGRRHFMIIRNVTADDEGVYSVIARLEPVGETKSTAEL 1352 Score = 149 bits (362), Expect = 6e-34 Identities = 158/746 (21%), Positives = 291/746 (39%), Gaps = 39/746 (5%) Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN---VTILD---KPSPPGKPNILE 1391 + ++ + T+ V I+++R EN G V I+D +PSPP N Sbjct: 4605 VKAEDLTATLSDVVENKEYIFRVRAENKAGIGQPSAATDPVKIMDPIERPSPPLNFNYTN 4664 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSY 1449 S+ + W+ P + G S I Y++E E T +W+ + + + LK Y Sbjct: 4665 QTRDSVQLSWETPISNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLYYRVSGLKFGQKY 4724 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKN--ITTEPNEDIELTCIFG 1506 +R A N +S+ ++ ++ + PT++ KN PN I + Sbjct: 4725 HYRVCAENAAGVSEPADAIG--PLLADDPHVGPTIDLSGFKNGLEVIVPNALI-IKVPIT 4781 Query: 1507 GVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 G P PK W K+L + + T Y ND V Sbjct: 4782 GYPVPKPKWTFGDKELTAGDRVSMVTKPTYTELVVAPSVRPDKGTYTLQLENDVTSVSGE 4841 Query: 1563 CVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-N 1620 V + P + + +H V W G P V Y + + K + Sbjct: 4842 IEVNVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSP---VSGYNVEKREVSRKTWVK 4898 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIM-- 1675 + + + + ++ +++ A N G ++ + V + P+ P ++ Sbjct: 4899 VISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDPPELLKW 4958 Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 R+ S +S+ + W+PP DGG + Y ++K + ++W D +++ + + L E Sbjct: 4959 RDKSAKSIFLLWEPPRYDGGAAVKGYIVDKCQRGTDKWEACGDPIPELK-FQVTGLIEGQ 5017 Query: 1736 EYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 Y +RV A N +G S ++ + I+ + P + + P++ Sbjct: 5018 WYAYRVRAVNRLGASRPCKATDEILAVDPKEPPEIQLDAKLLAGLTARAGTKIDLPADVL 5077 Query: 1795 GG-SPIIDY-KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 G P + + K ++ + ++ + + + ++ T Y + TS T Sbjct: 5078 GKPEPRVKWTKADLVLKPEE-RITIDTKPGHSTLS-IANTTRSDTATYIIEAVNTSGRAT 5135 Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 + + I L P P F +SE T+ S L W P +GGSP+ NYI+E + + W Sbjct: 5136 ATVDVNI---LDKPGPPAAFDISEITNESCCLAWNAPRDDGGSPVANYIVEMRPTDKEEW 5192 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 K+ + + K E +FR+SAEN G+ P E + + P PT Sbjct: 5193 QKLSATIKQTAFKATKLVPLK-EYVFRVSAENQYGIGTPAEHVPIVAKYSFDTPGAPTR- 5250 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 ++ + + V +W P+ DGG+P+ GY + D W++ K+ + F ++ L Sbjct: 5251 VQPSDITRDAVTLTWYEPDEDGGSPITGYWVERFDPETDKWIKSNKLPIKDTTFRVKGLP 5310 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEP 2058 Y R+ A N G +P +P Sbjct: 5311 TKKKYKFRVLAENLAGQGKPSVETDP 5336 Score = 141 bits (342), Expect = 2e-31 Identities = 120/439 (27%), Positives = 191/439 (43%), Gaps = 31/439 (7%) Query: 1643 YTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLE 1697 + + A N AG S+ +K+ D +P P+ + R+SV + W+ P+ +GG Sbjct: 4625 FRVRAENKAGIGQPSAATDPVKIMDPIERPSPPLNFNYTNQTRDSVQLSWETPISNGGSM 4684 Query: 1698 LTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +T Y IEK E ++W++ A + D+ Y + L +Y +RV A+N G SE ++ Sbjct: 4685 ITGYIIEKCEDGTDKWLRCNARLCPDLY-YRVSGLKFGQKYHYRVCAENAAGVSEPADA- 4742 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816 + D P + V + P+ PI Y V KW Sbjct: 4743 --IGPLLADDPHVGPTIDLSGFKNGLEVIV---PNALIIKVPITGYPVP----KPKWTFG 4793 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYA---RNEIGTSLPYTSDDKITIG-----KTLTPPSQ 1868 R+ ++ TY + A R + GT +D ++ + PS Sbjct: 4794 DKELTAGDRVSMVT-KPTYTELVVAPSVRPDKGTYTLQLENDVTSVSGEIEVNVIACPSA 4852 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 P++F V+E T V L W PE +GGSP++ Y +E + V K+W K+++ G E+ + Sbjct: 4853 PKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVEKREVSRKTWVKVIS-GVQDLEYTVT 4911 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 ++ E E +F + A N G P + V + ATVP PP L+ R + + W Sbjct: 4912 DVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDPPEL-LKWRDKSAKSIFLLW 4970 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P +DGGA + GY + W G + LKF + L E Y R+ A N + Sbjct: 4971 EPPRYDGGAAVKGYIVDKCQRGTDKWEACGD-PIPELKFQVTGLIEGQWYAYRVRAVNRL 5029 Query: 2048 GLSEPLE-SDEPFKVIPGE 2065 G S P + +DE V P E Sbjct: 5030 GASRPCKATDEILAVDPKE 5048 Score = 139 bits (337), Expect = 7e-31 Identities = 121/574 (21%), Positives = 231/574 (40%), Gaps = 30/574 (5%) Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375 P ++V + +++ K T+ + ++++ EN G ++ E+ Sbjct: 5476 PITNYVVEKRDVRRRTWQAVDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELED 5535 Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++L K P PP ++E+ +++ W+ P + G I YV+E +E T W+ Sbjct: 5536 SVLAKDTFTTPGPPYALTVVEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKS 5595 Query: 1431 KNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 + ++ + ++ + +F+ A NE + SE T + SP +E + Sbjct: 5596 GKTSGPESKYRVTDVDEGTEVQFQVRAENEAGVGHPSEPTVIMTIEDAISPPSPPLEVKI 5655 Query: 1489 K-------NIT---TEPNEDIELTCIFGGVPQPKVT-WYRDGKKLKTAKATYENRXXXXX 1537 NIT E N +T + + + W R + + ++ Sbjct: 5656 VDASREHINITWKAPEKNGGSPITGYHVELSEAETEKWMRINPR-PVKELRFKAEEGIIP 5714 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 I +D E+ P I ++ +DI G++ + Sbjct: 5715 EKKYVLRVRAINAIGVSDPSEISDGVFAKDPDSAPTIDVATQDIVVVE--GEKMDIKIPY 5772 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 IP P ++W K +L+ + +T + + + + K + YT+ N+ G+ + Sbjct: 5773 RAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTG 5832 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 V++ V P + + + E+++ S I W+PP +DGG + Y +E+ E ++ V Sbjct: 5833 TVSVTVIGLPGQCKD-ISPSELTKNSCKISWEPPENDGGSPILHYVLERREAQKKTFLPV 5891 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXX 1775 +V ++ ++ L N EY FRV A N +G E LE P++I+ P Sbjct: 5892 MS-GENVLSFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAG 5950 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWK--XXXXXXXXXARIQKLSIN 1832 N S+ +TW +GG PI Y +E I+++G +++ + L+ Sbjct: 5951 LNPTSN-SITVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEG 6009 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 YQFR+ A N G S P S I + PP Sbjct: 6010 KEYQFRVRAENIAGASDPSRSTPLIMAADPVDPP 6043 Score = 139 bits (336), Expect = 9e-31 Identities = 127/464 (27%), Positives = 193/464 (41%), Gaps = 29/464 (6%) Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIMR- 1676 + T K + + L + + A N G S +E ++ D + P P + Sbjct: 5495 VDTTVKDTKYTVTPLSEGSLYVFRVAAENAVGISEFCELEDSVLAKDTFTTPGPPYALTV 5554 Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 E+S+ V ++W+PP DGG +TKY IEK E RW+K Y + ++E Sbjct: 5555 VEVSKRHVDLKWEPPNSDGGRPITKYVIEKKEKVGTRWVKSGKTSGPESKYRVTDVDEGT 5614 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID--NESVYITWFPSEK 1793 E F+V A+N G SEP VI T D S +D E + ITW EK Sbjct: 5615 EVQFQVRAENEAGVGHP--SEPTVIMTIEDAISPPSPPLEVKIVDASREHINITWKAPEK 5672 Query: 1794 NGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQK---LSINTTYQFRIYARNEIGTSL 1849 NGGSPI Y VE+ + E +KW R + + Y R+ A N IG S Sbjct: 5673 NGGSPITGYHVELSEAETEKWMRINPRPVKELRFKAEEGIIPEKKYVLRVRAINAIGVSD 5732 Query: 1850 PYTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 P D + + P+ ++ VV E + + P P + Sbjct: 5733 PSEISDGVFAKDPDSAPTIDVATQDIVVVEGEKMDIKI----PYRAIPKPSMVWKKGDTE 5788 Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 +K + + VH ++ K +D ++ ++ EN++G T S +V Sbjct: 5789 LKTEDRLTLTCELNRVHLELLK-CKHEDAGVYTVTLENSLGSVTGTVSVTVI---GLPGQ 5844 Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 +P E+ N SW PE DGG+P+L Y + R+ K ++ V + N L F Sbjct: 5845 CKDISPSELT---KNSCKISWEPPENDGGSPILHYVLERREAQKKTFLPVMSGE-NVLSF 5900 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070 ++DL N Y R+ A N+IG E LE P +I + H D Sbjct: 5901 VVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPV-IIEEQKQHPD 5943 Score = 138 bits (333), Expect = 2e-30 Identities = 195/934 (20%), Positives = 359/934 (38%), Gaps = 76/934 (8%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNF 883 T PP+F + + +K + P + W++ I S+ I Sbjct: 217 TRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRIISRQ 276 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942 ++EL D DSG+Y C ASN G + A++ I E F++ L + Sbjct: 277 TTSSLELPSPTKD---DSGEYSCRASNKHGSDTCSAQLNITASEPARFLRKL-SNISIPM 332 Query: 943 GKTVILECQTS--HTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 + + LEC+ + + WY + K++ + + + + G+ C Sbjct: 333 SQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTLESLQECDNTTTGIYSC 392 Query: 1000 IVKD---QETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054 V + +E V T P F++KL D + LE + V W +DG+ Sbjct: 393 EVSNAFGREICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKDGK 452 Query: 1055 IIKPKKNKYDFEKRGHIRKL-YIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEI 1109 + +Y+ + + L + + G YSC I + C A+V V P Sbjct: 453 QLY-ASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTEPARF 511 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK-IYD 1167 + +L + + K E T + V W+KDG ++ S + G L+ +++ Sbjct: 512 VKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDTCILECLHE 571 Query: 1168 CDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 C+ G+YSCEV NS C A +T F L+L + + + Sbjct: 572 CNDATPGKYSCEVSNSIGTDICHANITTFTEPARFELKLKDKQVAMSKNLKLECTFTGAP 631 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTL-IIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + VTWYK + + ++ TL + +CT++ +Y+C + ++ E Sbjct: 632 KIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNSYGKDICHAE 691 Query: 1283 VVEF--PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V F P + V + +++G + L ++ + W + K + Sbjct: 692 VTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASYRCNTKVIG 751 Query: 1341 KSASLT-IKKVENTDAGIYKLRLENNCG----HADVEMNVTILDKPSPPGKPNILEIDSS 1395 + L + + + G Y + N G HA V + P+ KP+ I+ + Sbjct: 752 NTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKPS-EHIEDA 810 Query: 1396 SINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + E +G+ + + + + +EI+T++ V K+ ++ L+ + Y Sbjct: 811 EGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVS--FKSNVAVMCLRKATVTDSGVY 868 Query: 1455 AVNEVDISDASETTEYYKVIKET-KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 + S+ + T + V+ T + + PT + PLK +T E + L+C G P K+ Sbjct: 869 TCS---ASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKI 925 Query: 1514 TWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 W +D +++ ++ +T + Y C A N+ G + V I+ Sbjct: 926 QWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTIKD 985 Query: 1570 K--------------PVIT--ISN----EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWY 1607 K P T + N E+ K H V G + A + G P P V W Sbjct: 986 KAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFI-AKVGGDPIPNVKWM 1044 Query: 1608 K-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K ++ + NI K + S + IKE+ +S S +Y ASN G L V +K Sbjct: 1045 KGKWRQMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEK- 1103 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 K GP + + + + K P +D +++ + Sbjct: 1104 -KESGPEV---VKLKKTPSKQKSPKEDKDIDIVE 1133 Score = 138 bits (333), Expect = 2e-30 Identities = 97/364 (26%), Positives = 160/364 (43%), Gaps = 18/364 (4%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLK---VYDKPSKPEGPVIMREI--SRESVTI 1685 R++EL ++ + A N GT V K D P PV+ + +++SV++ Sbjct: 8310 RVQELVEGCEYEFRVTAENEIGTGDPSVPSKPILAKDPIVLPSPPVLPEAVDKTKDSVSL 8369 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIA 1743 W+ P DG ++ Y IE +P W+K + + + L E E+ FR++A Sbjct: 8370 SWRVPRHDGKGKIFGYLIEYQKPGAIEWVKANETPESCPDTKFVVTNLPEGEEFQFRIMA 8429 Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 N G SE A EP+ + LD P I +ES Y+TW E +GG+ I Y Sbjct: 8430 VNAAGKSEPAYVKEPVKVHDRLDKPGPPRNLAISE-ITSESAYLTWQKPEDDGGAVISHY 8488 Query: 1803 KVEIKQ-EGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 V+ K + W + + Q L T Y FR+ A N+ G S ++ I Sbjct: 8489 IVQKKDVAAENWVPVCAASKKLSLMAQYLMEGTQYLFRVAAENQFGRSAFVETNKPIKAV 8548 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 L PP P+N ++ V L+W P+ GGS IT +I+E + W TV Sbjct: 8549 DPLYPPGPPKNLHHVDADKTEVWLQWEWPDRTGGSEITGFIVEHQEEGATDWVTFKTVS- 8607 Query: 1921 SVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 + C + + E FR+ ++N +G+S P S + ++ PT ++++++ Sbjct: 8608 --NPQCHVTGLVEGKTYRFRVKSQNAIGISRPDTSVPITCQEKTLA---PTIEVDVKLIE 8662 Query: 1980 SNIV 1983 +V Sbjct: 8663 GLVV 8666 Score = 134 bits (323), Expect = 3e-29 Identities = 163/681 (23%), Positives = 266/681 (39%), Gaps = 61/681 (8%) Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 E +E EW + SI LK YRFR A N + S +ET E Y+ IKE Sbjct: 9932 EEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYE-IKEQ 9990 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533 + + L +T + + + + G P P W R + + A +N Sbjct: 9991 MFEPKIIMTEL--VTAKAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMC 10048 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-----KPVITISNEDIKQKHKVGD 1588 Y +A N G++E + + I+ +P IS+ D Sbjct: 10049 VLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDIPGPPEPPFEISDID---SDACTL 10105 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 W G + + + D +++ K RI +L + + A Sbjct: 10106 SWNKPTEDGGSNITNYV-VEKCDVSRGDWVTALSSCGKAG-CRIGKLIPGKEYIFRVRAE 10163 Query: 1649 NTAGTS----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 N G S S + K +D P +P I +++++ + + W P DGG +T Y I Sbjct: 10164 NRFGISDPLASERMVAKFPFDVPGEPLNCRI-NKVNKDCMFVAWDKPESDGGSPVTGYYI 10222 Query: 1704 EKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761 E+ E ++ W+K D V R E C L E EY FRV A N G + + +++ I + Sbjct: 10223 ERKERNSLLWVKANDSVVRTTEYPC-AGLIEGLEYTFRVSAINRAGQGKPSKKTDFITAR 10281 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXX 1820 T +D P + +V + W + +GGS II Y VE ++ G W Sbjct: 10282 TPVDAPG----KPEVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMRLPGDTWVRCNTSS 10337 Query: 1821 XXXARIQ----KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 R + L YQFR+ A+ + S P D I + PP Sbjct: 10338 QNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILVSAENVPP---------- 10387 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE---- 1932 SV +K P G + K + +W+K + E + + Sbjct: 10388 RIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFSL 10447 Query: 1933 KDEIIFRISAENTVGVSLPTESQSVRLE---KHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 + + ++ A N G+ S + E K +P PP A +++ + S+ V SW Sbjct: 10448 SLDAVTKLHAGN-YGIHAANASGNTTAEIQLKILDIPGPP-ASVKLDEILSDRVKLSWEA 10505 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P DGG+P+ Y + R+ ++ W +V K+ +T + ++ L E H Y R+ A N G Sbjct: 10506 PLVDGGSPITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAENHYG 10565 Query: 2049 -----LSEPLESDEPFKVIPG 2064 +SEP+ + PF +PG Sbjct: 10566 TGDAIISEPVVARNPF-TVPG 10585 Score = 125 bits (301), Expect = 2e-26 Identities = 114/476 (23%), Positives = 193/476 (40%), Gaps = 15/476 (3%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 V V++ P P + K E +E+ T K I I LK ++ + A N+ Sbjct: 9914 VEPVVQPPPEPVAAEEEKEEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSM 9973 Query: 1652 GTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 G+S T + Y+ K E +IM E+ + + G ++ E + Sbjct: 9974 GSSLPTETREAYEIKEQMFEPKIIMTELVTAKAGAKLRVEALVSGKPAPACQWKRGENNV 10033 Query: 1711 NRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 ++A +++ I+ ++ + ++A+N G E ++ I+I+ D+P Sbjct: 10034 VSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAENSSGKIE--QTLKIIIR---DIPGP 10088 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXX-XXXXARIQ 1827 ID+++ ++W ++GGS I +Y VE + W RI Sbjct: 10089 PEPPFEISDIDSDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWVTALSSCGKAGCRIG 10148 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 KL Y FR+ A N G S P S+ ++ P +P N +++ + + W Sbjct: 10149 KLIPGKEYIFRVRAENRFGISDPLASE-RMVAKFPFDVPGEPLNCRINKVNKDCMFVAWD 10207 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 +PES+GGSP+T Y IE K W K E+ + E E FR+SA N G Sbjct: 10208 KPESDGGSPVTGYYIERKERNSLLWVKANDSVVRTTEYPCAGLIEGLEYTFRVSAINRAG 10267 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 P++ + T P P E+ V N V W P+ DGG+ ++GY + Sbjct: 10268 QGKPSKKTDFITAR--TPVDAPGKP-EVLDVTKNAVSLVWTKPKNDGGSKIIGYYVEAMR 10324 Query: 2008 VTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + W+ N + + L E Y R+ A+ + +S P E +P V Sbjct: 10325 LPGDTWVRCNTSSQNVPREEYTATGLEEGANYQFRVIAKTAVNISRPSEITDPILV 10380 Score = 121 bits (291), Expect = 3e-25 Identities = 99/402 (24%), Positives = 169/402 (42%), Gaps = 15/402 (3%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 GS + L + P P W + IK + + ++KV DAG Y L Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863 Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 L++ G + V +LD P PP I E S +I WDEP G S I Y+V+ ++ Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPLNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRD 10923 Query: 1422 IDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 + W +V + TKT I++L+ SY FR A N+ I + ET + ++ ++ Sbjct: 10924 AERKAWSNVTTSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVD---AVRASEQP 10980 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQ--PKVTWYRDGKKLKTAKATYENRXXXXXX 1538 P ++ +T + I G + V +G+ K + Sbjct: 10981 GPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGED-KWKELLRSKNMQYSAK 11039 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK------HKVGDEWLV 1592 Y+ A ND G+ + + K + + + D++ K G + Sbjct: 11040 DLVEGREYKYRVFATNDSGDGPVK-ELSVLAKDINVLPSCDLRDLPNLNYIAKEGSNVRL 11098 Query: 1593 TAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 I G P P V W K ++ L + + + + + I++ +R+ +SKYTI N+A Sbjct: 11099 KIPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDASKYTITLRNSA 11158 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 GT + ++V KP P GP+ +E++ + T++W P DD Sbjct: 11159 GTKESTIFVRVVGKPGIPNGPIKFKEVTADGATLKWSAPKDD 11200 Score = 120 bits (290), Expect = 3e-25 Identities = 81/300 (27%), Positives = 133/300 (44%), Gaps = 9/300 (3%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW---KXXXXX 1819 LD+P + ++ V ++W +GGSPI +Y V+ ++ + +W Sbjct: 10480 LDIPGPPASVKLDEIL-SDRVKLSWEAPLVDGGSPITNYVVDKRETSRAEWAQVSAKISR 10538 Query: 1820 XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 +++L YQFR+ A N GT S+ + T P V++ T Sbjct: 10539 DTTECSVERLIEGHEYQFRVRAENHYGTGDAIISEP-VVARNPFTVPGACDPPVLTNITK 10597 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 +T+ W EP +G SPI Y++E + K +WTKI + + E + FR Sbjct: 10598 EHMTVSWKEPSDDGKSPILGYLVEKRETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFR 10657 Query: 1940 ISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 + A N G+ P++ S + P PP +P I S I +T W P DGG+ + Sbjct: 10658 VIAVNKAGLGKPSDPSNAASALDPLYPPGPPISPKAIDTTNSTIKLT-WTKPANDGGSDI 10716 Query: 1999 LGYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 LGY + + + T W+ ++ + + L EN Y +R+ A N+IG S+P E E Sbjct: 10717 LGYLVECKRINTTDWIRCNVPKNLQDTNYVVTGLLENSEYQLRVSAVNKIGFSQPCEVPE 10776 Score = 119 bits (287), Expect = 8e-25 Identities = 88/286 (30%), Positives = 132/286 (46%), Gaps = 14/286 (4%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---W-KXXXXXXXXXARIQKLSINTT 1834 I ES Y+TW E NGGS + +Y VE + KK W + + KL T Sbjct: 6876 IKAESCYLTWDAPEDNGGSDLTNYIVEKRDASKKKSDWDQLTCCIMDRRYGVYKLEAYGT 6935 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 YQF+I A N+ G S S+ K+ + P P+ + T S+ + W P+ NGG Sbjct: 6936 YQFQIKAENKYGISDGCESE-KVVLKDPFGLPGPPQRPRIISHTRSSMVVTWEPPKDNGG 6994 Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS 1949 S I Y +E + W+++ VT E+ + ++ E E FR+ A+N GV Sbjct: 6995 STIQGYWLEKRERGAVYWSRVNRAPVTKPAVKGLEYNVLHLIEGAEYKFRVMAQNAAGVG 7054 Query: 1950 LPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 P+E+ + V PS P AP+ S++ + SW P+ DGG+P+ GY + ++D Sbjct: 7055 PPSEATECVFALDPRNPPSQPPAPVVTDKSPSSVSL-SWTPPDRDGGSPIKGYIVEVQDE 7113 Query: 2009 TKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 W + D + T + + L EN RI A N G SEP Sbjct: 7114 GSHEWKRINTPDKLILTNSYTVPGLKENKKCRFRIVAVNAAGESEP 7159 Score = 118 bits (285), Expect = 1e-24 Identities = 87/292 (29%), Positives = 134/292 (45%), Gaps = 18/292 (6%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXAR-IQKLSINTT 1834 I N SV TW +GGS II+Y +E K W + KL Sbjct: 6180 IRNTSVVCTWDAPLDDGGSEIINYILEKKDNTSDDIGWVTVTSTHKGYNYPVTKLIEGKE 6239 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y FR+ A N+ G P S+ + + PP P + E TS +V L W EP+ NG Sbjct: 6240 YIFRVTAENKFGCGHPCYSEPLVAKNQ-FEPPDAPNVPRIGEVTSSTVALSWHEPKDNG- 6297 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG---VSLP 1951 SPI Y +E + V K W ++ + S +E + E +FR+ AEN G S+P Sbjct: 6298 SPILGYWVERREVNSKYWIRVNSNLLSALNVKVEGLMEGLVYVFRVCAENLAGPGEFSVP 6357 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 T+ Q+ +P P P + + + I + SW P ++GG +LGY++ V + Sbjct: 6358 TDPQAAM---DPILPPGPPVPKIVDVTNTTIDI-SWQPPLYNGGGEILGYHVERCLVGEK 6413 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE-----IGLSEPLESDEP 2058 W+ + K+ + L+E Y +R+YA NE G++EP+++ EP Sbjct: 6414 DWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEP 6465 Score = 117 bits (282), Expect = 3e-24 Identities = 67/228 (29%), Positives = 113/228 (49%), Gaps = 9/228 (3%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 +++I +N+ GT + + D I + P +N V ++ V+L W EPES+GGS Sbjct: 4429 RYKIVIKNKHGTGEAFINLDVIDV------PGPVKNLHVVDTADGEVSLAWEEPESDGGS 4482 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTES 1954 I Y++E + VK K+WT + T + E+C+ + + FR+ A N VG T Sbjct: 4483 KILAYVVERRDVKRKTWT-MATDRADIPEYCVGGLHRDNMYFFRVCARNRVGNGETVTTD 4541 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 ++V+ + VP P + + +V SW P +DGG+ + Y I +RD T W Sbjct: 4542 EAVQAKNKFDVPDAPQKFM-VGVVNRFGATVSWEPPLFDGGSEVTSYIIELRDRTSVKWE 4600 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 V L + D+ EN Y+ R+ A N+ G+ +P + +P K++ Sbjct: 4601 PAMVVKAEDLTATLSDVVENKEYIFRVRAENKAGIGQPSAATDPVKIM 4648 Score = 116 bits (279), Expect = 7e-24 Identities = 69/260 (26%), Positives = 120/260 (46%), Gaps = 5/260 (1%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + + A I+G P P V W K +++ + I T + +++ ++++ R + KY + Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 + +G V +KV D P P ++++E S++S +I W PL DGG E+T Y ++K Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPLN-LMIKETSKDSASILWDEPLIDGGSEITGYIVDKR 10922 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 + + W V ++ I+ L Y FRV+AQN G E E+ V + Sbjct: 10923 DAERKAWSNVT-TSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAVRASEQPG 10981 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826 P + +S ++W +GGS II Y +E+ KWK Sbjct: 10982 P---VMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGEDKWKELLRSKNMQYSA 11038 Query: 1827 QKLSINTTYQFRIYARNEIG 1846 + L Y++R++A N+ G Sbjct: 11039 KDLVEGREYKYRVFATNDSG 11058 Score = 113 bits (271), Expect = 7e-23 Identities = 153/694 (22%), Positives = 280/694 (40%), Gaps = 82/694 (11%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F K Q + +G + LE I + + W G++ + + + C Sbjct: 698 PARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAYASYRCNTKVIGNT---C 754 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751 + + + G Y+ +N +G ++ + T K PP + P + + +G+ Sbjct: 755 VLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKKPSEHIEDAEGKL 814 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 V L ++V G+ ++ W K+NK + + S ++ L+ V D GVYT A N Sbjct: 815 VKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKATVTDSGVYTCSASN 874 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G A V+ + E PP F + +TV E + L V +P I W ++ Sbjct: 875 EAGTASFQVVVNITE----QKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKD 930 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKV 928 ++ S + F L I N S+ D+GDY C A+N+AG +VTI D V Sbjct: 931 RREVTSSASTKMTFVDGTATLEI-NQASKTDAGDYLCKATNNAGSEFSKTKVTIKDKAGV 989 Query: 929 T------------FVKHLQKSYETEEGKTV-ILECQTSHTVS---------TKWYHNK-K 965 K L + EE K++ I+E T+ ++ KW K + Sbjct: 990 APAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKWMKGKWR 1049 Query: 966 EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV---KETIPE 1018 +++ I Q+G+ D G +C+ ++ E ST L V KE+ PE Sbjct: 1050 QMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKESGPE 1109 Query: 1019 FIR-----KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 ++ Q ++KD+ I+E+ N + + +E+ + + + ++K Sbjct: 1110 VVKLKKTPSKQKSPKEDKDIDIVELLRNVDPKE--YEKYARMYGITDFRGLLQAIEFLKK 1167 Query: 1074 LYIRNTSVHDEGE-YSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132 + +E E + ++ D E + P ++ + +Q +A FE E+ Sbjct: 1168 EKGEESGRPEEDEDLAKLVSDLQRRMENSE---PVTLLKDITDQTTQLNKEAVFECEIKV 1224 Query: 1133 G--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190 + + W+KD +++ ++ + + G +Q LKI + D Sbjct: 1225 NYPEITLAWYKDTQKLETNDKYDIKLVGDRQILKIKNSD--------------------- 1263 Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 I FT R+ I+V A E+ + VTWYK ++++ K+T + ++ Sbjct: 1264 ----QIQFTKRIQN-IVVNERQSATFECELSFDNAVVTWYKDAWELKESLKYTFKCEGRR 1318 Query: 1251 RTLIIRKCTEDDQCEYTCVL-LDAKSTTKLKVEV 1283 +IIR T DD+ Y+ + L+ TK E+ Sbjct: 1319 HFMIIRNVTADDEGVYSVIARLEPVGETKSTAEL 1352 Score = 109 bits (263), Expect = 6e-22 Identities = 67/207 (32%), Positives = 98/207 (47%), Gaps = 7/207 (3%) Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 +DD T+ PP Q +S T S+T+ W EPES+GGSPIT Y +E K K W Sbjct: 7542 ADDSCTLLIQQVPPGQCEKPTISSVTIDSMTVNWEEPESDGGSPITGYWLERKETTSKRW 7601 Query: 1913 TKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPS 1967 +++ V H + + E + +FR+SA N GV P+E S+ + PS Sbjct: 7602 SRVTRDPVRPMPMGVSHRVTGLIEGSQYLFRVSAINAAGVGPPSEPSEPTFAREPIAPPS 7661 Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027 PPT ++ W P DGG+ ++GY + ++ W++ +V KF Sbjct: 7662 PPTP--KVTDWTKTTADLEWIPPLKDGGSKIIGYFVEYKEEGTEAWVKAKDKEVRGTKFV 7719 Query: 2028 IRDLSENHTYMIRIYARNEIGLSEPLE 2054 I L EN + R+ A N GL EP E Sbjct: 7720 ITGLKENALFKFRVIALNAAGLGEPGE 7746 Score = 105 bits (252), Expect = 1e-20 Identities = 185/990 (18%), Positives = 365/990 (36%), Gaps = 83/990 (8%) Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA--DILEGIPPTFSKKPKAQYVDEGSDI 651 +T+ L + +P D E + A +I P F +K + + Sbjct: 277 TTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITASEPARFLRKLSNISIPMSQKL 336 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 LEC+ + + W G+++ + + + C++ + G Y+ Sbjct: 337 RLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNS---CTLESLQECDNTTTGIYSCE 393 Query: 712 AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 N G I T EP + ++ L M + + + L G P+ +TW K+ Sbjct: 394 VSNAFGRE---ICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECTFTGAPKLFVTWYKD 450 Query: 772 NKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-VITVEEPTE 827 K + A TK ++ + L + G Y+ + N G + A V+ V EP Sbjct: 451 GKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTDKCHAQVVAVTEPAR 510 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 F+ + ++ + ++L T P +TWY++ + + S G+ Sbjct: 511 -------FVKKLTDVAIPVTQKLRLECTFTGAPKIFVTWYKDGKQLYASYRYNTKVIGDT 563 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 L + ++ G Y C SNS G A +T E F L K + K + Sbjct: 564 CILECLHECNDATPGKYSCEVSNSIGTDICHANITTFTEPARFELKL-KDKQVAMSKNLK 622 Query: 948 LECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQ 1004 LEC + + WY + K++ G + G C V + Sbjct: 623 LECTFTGAPKIFVTWYKDGKQLYASYRYNTTVVGNTCTLECLHECTKETPGKYSCEVSNS 682 Query: 1005 ETSTMLVVKETI----PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPK 1059 + + T F++ L D +++ LE V W +DG+ Sbjct: 683 YGKDICHAEVTTFSGPARFVKTLTDQSLQQGQKLRLEASFKGIGKIFVTWYKDGKQAY-A 741 Query: 1060 KNKYDFEKRGHIRKL-YIRNTSVHDEGEYSCILRDES----CTAEVTV---VELPPEIIT 1111 + + + G+ L Y+ + G+YSC + +E C A VT+ ++PP T Sbjct: 742 SYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGSDICHALVTLGTERKIPP-TFT 800 Query: 1112 RLQNQKVN--KGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 + ++ + +G E ++ L V W+KD EI S+ ++ + + Sbjct: 801 KKPSEHIEDAEGKLVKLESRVSGSQPLSVIWYKDNKEINTSDIYDVSFKSNVAVMCLRKA 860 Query: 1169 DLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI-PD 1222 + D+G Y+C N TA ++ + E T +P + + V L+ + Sbjct: 861 TVTDSGVYTCSASNEAGTASFQVVVNITEQKRPPTFDIPLKPMTVSEGERLNLSCHVCGS 920 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--------AK 1274 + + W K + + + + TL I + ++ D +Y C + K Sbjct: 921 PPVKIQWMKDRREVTSSASTKMTFVDGTATLEINQASKTDAGDYLCKATNNAGSEFSKTK 980 Query: 1275 STTKLKVEVV-----------EFPPKI-----VDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 T K K V + K+ ++ + I T + P PN Sbjct: 981 VTIKDKAGVAPAAAPAAPTTPQATKKLDNLFFIEEPKSIHIVEKGTATFIAKVGGDPIPN 1040 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 +W + K + + +I K + L IK+V +D+G Y+ N H ++E + Sbjct: 1041 VKW-MKGKWRQMTHGGRINIQQKGQESKLEIKEVTKSDSGQYRCVASNK--HGEIECSTD 1097 Query: 1377 I-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 + +D+ G P ++++ + P+ + I+ + + ++ + IT Sbjct: 1098 LNVDEKKESG-PEVVKLKKTPSK--QKSPKEDKDIDIVELLRNVDPKEYEKYARMYGITD 1154 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 + +Q ++ + E D A ++ + ++ + + T+ K + + TT+ Sbjct: 1155 FRGLLQAIEFLKKEKGEESGRPEEDEDLAKLVSDLQRRMENS--EPVTLLKDITDQTTQL 1212 Query: 1496 NEDIELTC-IFGGVPQPKVTWYRDGKKLKT 1524 N++ C I P+ + WY+D +KL+T Sbjct: 1213 NKEAVFECEIKVNYPEITLAWYKDTQKLET 1242 Score = 103 bits (246), Expect = 7e-20 Identities = 95/382 (24%), Positives = 169/382 (44%), Gaps = 22/382 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437 P PP P ++ +S+I + W +P N G S I+ Y+VE + I+TT+WI KN+ T Sbjct: 10685 PGPPISPKAIDTTNSTIKLTWTKPANDGGSDILGYLVECKRINTTDWIRCNVPKNLQDTN 10744 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKN-ITTEP 1495 + L NS Y+ R AVN++ S E E + + K+ + ++ LK+ + Sbjct: 10745 YVVTGLLENSEYQLRVSAVNKIGFSQPCEVPEKH-IAKDVFVTPEAELDAELKDTLVLTA 10803 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCI 1551 ++L G P P+VTW + +K + T + Y Sbjct: 10804 GSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDAGKYILN 10863 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNG 1610 + G + +V + P + N IK+ K L +I+G E+ Y Sbjct: 10864 LDSVSGMKMYTVIVKVLDTPGPPL-NLMIKETSKDSASILWDEPLIDG--GSEITGYIVD 10920 Query: 1611 NKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + K + N+TT + +I++L+ S + + A N G T+ + S+ Sbjct: 10921 KRDAERKAWSNVTTSCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAV-RASEQ 10979 Query: 1670 EGPVIMRE---ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 GPV+ + ++++S T+ WK P+ DGG + Y +E + ++W ++ ++++ Y Sbjct: 10980 PGPVMDFKTLLVTKDSCTLSWKKPISDGGSRIIAYVLEVLNGE-DKWKELLR-SKNMQ-Y 11036 Query: 1727 CIQKLNENCEYMFRVIAQNPVG 1748 + L E EY +RV A N G Sbjct: 11037 SAKDLVEGREYKYRVFATNDSG 11058 Score = 100 bits (240), Expect = 4e-19 Identities = 120/523 (22%), Positives = 204/523 (39%), Gaps = 29/523 (5%) Query: 1554 NDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N HG SC V + KP + ++I+ V W G I K N Sbjct: 6152 NAHGFATASCDVNVLDKPGPPVNFGFDEIRNTSVVCT-WDAPLDDGGSEIINYILEKKDN 6210 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKP 1666 ++ +T+ K + +L + + A N G S V ++ P Sbjct: 6211 TSDDIGWVTVTSTHKGYNYPVTKLIEGKEYIFRVTAENKFGCGHPCYSEPLVAKNQFEPP 6270 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 P P I E++ +V + W P D+G + Y +E+ E ++ WI+V Sbjct: 6271 DAPNVPRI-GEVTSSTVALSWHEPKDNGS-PILGYWVERREVNSKYWIRVNSNLLSALNV 6328 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNESVY 1785 ++ L E Y+FRV A+N G E S P + A+D + + N ++ Sbjct: 6329 KVEGLMEGLVYVFRVCAENLAGPGEF--SVPTDPQAAMDPILPPGPPVPKIVDVTNTTID 6386 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYAR 1842 I+W P NGG I+ Y VE G+K W + + L+ Y R+YA Sbjct: 6387 ISWQPPLYNGGGEILGYHVERCLVGEKDWVRCTEFRCKDRKYTVTGLTEGADYNLRVYAV 6446 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 NE G P ++ + + P + V P G P+ + Sbjct: 6447 NEGGHGAPGMTEP-VQAKEPEEAPGVEFDISVRNGVIIRAGETLRLPAVVTGRPVPE--V 6503 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 ++ + + V + + I+ D I++I+ N G T+S SV+++ Sbjct: 6504 KWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPSG----TKSVSVKVD 6559 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 VP P L+ V ++ +W P +GG+ ++GY + +D ++ + ++ Sbjct: 6560 V-MDVPGP-VVDLKTVNVSKKMISLTWSDPLDNGGSDIMGYVVERKDAKMHIYRQ--PLE 6615 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 V K +I L + YM R+ ARN+ GL P+E V P Sbjct: 6616 VAACKCDIVGLLDGEEYMFRVVARNKFGLGAPVELGPVLAVDP 6658 Score = 99 bits (238), Expect = 7e-19 Identities = 132/594 (22%), Positives = 228/594 (38%), Gaps = 32/594 (5%) Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVR 1138 S+H E +++ L E+ E+PP ++ N + N GN FE E+ + + + Sbjct: 199 SIHVEEKHT--LTGETSQGFTRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFK 256 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEP 1194 WFK GSEI+ S+ +++ L++ DD+GEYSC G+ C+A L + Sbjct: 257 WFKAGSEIKQSDKVRIISRQTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITAS 316 Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF-TLISDVKKRT 1252 LR I +P + L + D L VTWYK + + ++ T ++D Sbjct: 317 EPARFLRKLSNISIPMSQKLRLECKFTGDRKLFVTWYKDGKQLYASYRYNTTVTDNSCTL 376 Query: 1253 LIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 +++C Y+C + +A + V V P + V + I + L Sbjct: 377 ESLQECDNTTTGIYSCEVSNAFGREICHATVTAVTEPARFVKKLTDMSIPMSQKLRLECT 436 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKLRLENNCGHA 1369 + P+ W + K + + S S L + + N G Y + N G Sbjct: 437 FTGAPKLFVTWYKDGKQLYASYRYNTKVTSNSCILECLHECNNETTGRYSCEVSNIYGTD 496 Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 V + +P+ K + ++ E TG I +V Y++ + S Sbjct: 497 KCHAQVVAVTEPARFVK-KLTDVAIPVTQKLRLECTFTGAPKI--FVTWYKD-GKQLYAS 552 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 + TK L+ ++S++ T + I T + E LK Sbjct: 553 YRYNTKVIGDTCILECLHECNDATPGKYSCEVSNSIGTDICHANI-TTFTEPARFELKLK 611 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX------XXX 1543 + +++++L C F G P+ VTWY+DGK+L A Y Sbjct: 612 DKQVAMSKNLKLECTFTGAPKIFVTWYKDGKQL-YASYRYNTTVVGNTCTLECLHECTKE 670 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKP---VITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y C N +G+ V P V T++++ ++Q G + + A +GI Sbjct: 671 TPGKYSCEVSNSYGKDICHAEVTTFSGPARFVKTLTDQSLQQ----GQKLRLEASFKGIG 726 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIR-IKELKRSHSSKYTIEASNTAGT 1653 V WYK+G + N T V+ + E + KY+ E N G+ Sbjct: 727 KIFVTWYKDGKQAYASYRCNTKVIGNTCVLEYLHECDENTPGKYSCEVMNEDGS 780 Score = 99.1 bits (236), Expect = 1e-18 Identities = 74/291 (25%), Positives = 120/291 (41%), Gaps = 19/291 (6%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK--PSKPEGPVIMREI---SRESVTIE 1686 + L +H ++ ++A N G + + P +P GPV ++ S+ S+T+ Sbjct: 9602 VTSLLPNHEYQFRVKAENEIGVGDASKPSRTFTARDPVEPPGPVSNLKVTDSSKTSITLA 9661 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNR-----WIKVADVDRDVET-YCIQKLNENCEYMFR 1740 W P DGG L Y +E + W + + + T + + L+E EY FR Sbjct: 9662 WTKPTYDGGAPLIGYVVEIRVKGTGKKGDEGWKRCNVAAQLIGTEFTVSSLDEKLEYEFR 9721 Query: 1741 VIAQNPVGFS-----EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 V + +S A E V LD P + S +TW P E +G Sbjct: 9722 VTRDDSGKYSLNVSSPAGEKAVFVNVKVLDTPGPVDGLEVTD-MTMSSCNLTWSPPETDG 9780 Query: 1796 GSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 GS + Y VE ++ + K W +I L T Y FR+ A NE G +P + Sbjct: 9781 GSNVTHYIVEKREIDRKTWATVKANVEKTTFKISNLVPGTEYYFRVVAVNEYGPGVPRVT 9840 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 ++ P P+ V E + S T+ W +P +GG+ I Y+I++ Sbjct: 9841 PKSYLASDPVSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVIDY 9891 Score = 87.8 bits (208), Expect = 3e-15 Identities = 53/191 (27%), Positives = 96/191 (50%), Gaps = 9/191 (4%) Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 I K L P P N ++ E++ S ++ W EP +GGS IT YI++ + + K+W+ VT Sbjct: 10876 IVKVLDTPGPPLNLMIKETSKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSN-VTT 10934 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRM 1977 + IE+++ FR+ A+N G+ P E+ +VR A+ P + + Sbjct: 10935 SCTKTSFKIEDLEPGRSYCFRVLAQNQYGIGEPCETVDAVR----ASEQPGPVMDFKTLL 10990 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 V + SW P DGG+ ++ Y + + + + W E+ + ++++ +DL E Y Sbjct: 10991 VTKDSCTLSWKKPISDGGSRIIAYVLEVLN-GEDKWKEL--LRSKNMQYSAKDLVEGREY 11047 Query: 2038 MIRIYARNEIG 2048 R++A N+ G Sbjct: 11048 KYRVFATNDSG 11058 Score = 81.8 bits (193), Expect = 2e-13 Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 5/170 (2%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGI 1357 + G+ + L D P+P +W ++K + +ID+K ++L+I +D Sbjct: 5065 RAGTKIDLPADVLGKPEPRVKWTKADLVLKP--EERITIDTKPGHSTLSIANTTRSDTAT 5122 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 Y + N G A ++V ILDKP PP +I EI + S + W+ P + G S + Y+V Sbjct: 5123 YIIEAVNTSGRATATVDVNILDKPGPPAAFDISEITNESCCLAWNAPRDDGGSPVANYIV 5182 Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 E + D EW + I +T L Y FR A N+ I +E Sbjct: 5183 EMRPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYGIGTPAE 5232 Score = 77.8 bits (183), Expect = 3e-12 Identities = 52/180 (28%), Positives = 75/180 (41%), Gaps = 3/180 (1%) Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 F PKI+ E K G+ + + P P +W + L Sbjct: 9992 FEPKIIMTEL-VTAKAGAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVL 10050 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404 IK V D+G Y L EN+ G + + + I D P PP P I +IDS + + W++P Sbjct: 10051 IIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIRDIPGPPEPPFEISDIDSDACTLSWNKP 10110 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 G S I YVVE ++ +W+ ++ + K I L Y FR A N ISD Sbjct: 10111 TEDGGSNITNYVVEKCDVSRGDWVTALSSCGKAGCRIGKLIPGKEYIFRVRAENRFGISD 10170 Score = 75.8 bits (178), Expect = 1e-11 Identities = 91/450 (20%), Positives = 177/450 (39%), Gaps = 26/450 (5%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 EQ P F L+P +G + C V G P +I W + + S +M + D Sbjct: 889 EQKRPPTFDIPLKPMTVSEGERLNLSCHVCGSPPVKIQWMKDRREVTSSASTKMTF-VDG 947 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 ATL I + DAG + C A N AG S T++ ++ + + Sbjct: 948 TATLEINQASKTDAGDYLCKATNNAGSEFSKTKVTIK-----DKAGVAPAAAPAAPTTPQ 1002 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVA 683 L+ + F ++PK+ ++ E ++ P P++ W+ K ++ I++ Sbjct: 1003 ATKKLDNL--FFIEEPKSIHIVEKGTATFIAKVGGDPIPNVKWMKGKWRQMTHGGRINIQ 1060 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 + S L+I V K G Y VA N+ GE L + ++ P+V++ K+ Sbjct: 1061 QKGQE----SKLEIKEVTKSDSGQYRCVASNKHGEIECSTDLNVDEKKESGPEVVKLKKT 1116 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGV 802 ++ +V R + + K + T G +I LK +K ++ G Sbjct: 1117 PSKQKSPKEDKDIDIVELLR-NVDPKEYEKYARMYGITDFRGLLQAIEFLKKEKGEESG- 1174 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PV 861 + E E +A+ +++ + EN+EP + + T + + N P Sbjct: 1175 ---RPEEDEDLAK---LVSDLQRRMENSEPVTLLKDITDQTTQLNKEAVFECEIKVNYPE 1228 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 ++ WY++ + + ++ G+ L I N D + + + N ++ + Sbjct: 1229 ITLAWYKDTQKLETNDKYDIKLVGDRQILKIKNSDQIQFTKRIQNIVVNERQSATFECEL 1288 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 + D VT+ K ++E +E +C+ Sbjct: 1289 SFDNAVVTWYK---DAWELKESLKYTFKCE 1315 Score = 69.7 bits (163), Expect = 8e-10 Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 21/271 (7%) Query: 1803 KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 K E +++ ++W I L Y+FR+ ARN +G+SLP + + I + Sbjct: 9931 KEEKEEKKEEWTPYTVVKGLSISIAGLKEGRKYRFRVAARNSMGSSLPTETREAYEIKEQ 9990 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 + P +++E + K G P ++K + + Sbjct: 9991 MFEP----KIIMTELVTAKAGAKLRVEALVSGKPAP--ACQWKRGENNVVSSSRLAVHKS 10044 Query: 1923 HEHC---IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 C I+++ +D + + AEN+ G T +R +P PP P EI + Sbjct: 10045 QNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKIIIR-----DIPGPPEPPFEISDID 10099 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 S+ SW P DGG+ + Y + DV++ W+ I L Y+ Sbjct: 10100 SDACTLSWNKPTEDGGSNITNYVVEKCDVSRGDWV-TALSSCGKAGCRIGKLIPGKEYIF 10158 Query: 2040 RIYARNEIGLSEPLESDE-----PFKVIPGE 2065 R+ A N G+S+PL S+ PF V PGE Sbjct: 10159 RVRAENRFGISDPLASERMVAKFPFDV-PGE 10188 Score = 66.1 bits (154), Expect = 1e-08 Identities = 68/315 (21%), Positives = 129/315 (40%), Gaps = 17/315 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284 + W K + ++ ++ TL ++ + L + KC +D YT L ++ T + V V+ Sbjct: 5780 MVWKKGDTELKTEDRLTLTCELNRVHLELLKCKHEDAGVYTVTLENSLGSVTGTVSVTVI 5839 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343 P + D K ++ P +++ + +K K P + ++ Sbjct: 5840 GLPGQCKDISPSELTKNSCKISWEPPENDGGSPILHYVLERREAQK-KTFLPVMSGENVL 5898 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEM-NVTILDK----PSPPGKPNILEIDSSSI 1397 S +K + ++++ N G + +E+ N I+++ P PP + L S+SI Sbjct: 5899 SFVVKDLMLNSEYHFRVKAVNKIGSGEFLELRNPVIIEEQKQHPDPPIEVAGLNPTSNSI 5958 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITK-TQTSIQNLKTNSSYRFRAYA 1455 + W P G I Y++E E D + V N+ ++ L Y+FR A Sbjct: 5959 TVTWMAPPYDGGCPITGYIIEKIEKDGDRFERCVPNLVPGFSYTVTGLTEGKEYQFRVRA 6018 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPK 1512 N SD S +T ++ + P V + ++ + E+I L G P P Sbjct: 6019 ENIAGASDPSRSTPL--IMAADPVDPPQVTLFARIASGLSIKKGEEIRLDAYISGSPYPT 6076 Query: 1513 VTWYRDGKKLKTAKA 1527 VTW R+ + ++ A Sbjct: 6077 VTWLRNDENVRQPPA 6091 Score = 66.1 bits (154), Expect = 1e-08 Identities = 46/210 (21%), Positives = 92/210 (43%), Gaps = 16/210 (7%) Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT---- 1376 + + K ++ TK + + SL + + ++++R EN G+ + Sbjct: 7313 YFIEKKTVEGKAWTKVNPACTTQSLVVPDLIEGQEYLFRIRAENRFGYGPHTTTIEGTKA 7372 Query: 1377 --ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT-----EW-- 1427 + P PP + I+++ + + W P+N G + + +Y +E D++ W Sbjct: 7373 RDPIHPPDPPTRVKIIDVSKGIVTLTWKPPKNDGGAPVTHYNIERLWWDSSGNQQESWRQ 7432 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 + ++I T +++L + Y FR AVNEV S S T +I + + ++P +E P Sbjct: 7433 CNRRDIDTTTFKVEDLHEGAEYEFRVKAVNEVGASRPSSTAG--PIIVKDQNRAPFIELP 7490 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 + + E D + G P P +TW + Sbjct: 7491 -EFMEIEQGTDAHIVAKIKGCPFPTLTWQK 7519 Score = 65.3 bits (152), Expect = 2e-08 Identities = 37/175 (21%), Positives = 67/175 (38%), Gaps = 1/175 (0%) Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 V +P P +W K + L + D G Y L+LEN+ Sbjct: 4778 VPITGYPVPKPKWTFGDKELTAGDRVSMVTKPTYTELVVAPSVRPDKGTYTLQLENDVTS 4837 Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 E+ V ++ PS P + E+ +++ W+ PE+ G S + Y VE +E+ W+ Sbjct: 4838 VSGEIEVNVIACPSAPKDFKVAEVTRHHVHLMWEAPEHDGGSPVSGYNVEKREVSRKTWV 4897 Query: 1429 SV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 V + + ++ ++ Y F A N+ + + E V + P Sbjct: 4898 KVISGVQDLEYTVTDVIEGKEYLFSVIACNKCGPGEPAYIDEPVNVSSPATVPDP 4952 Score = 63.3 bits (147), Expect = 7e-08 Identities = 68/325 (20%), Positives = 135/325 (41%), Gaps = 23/325 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252 P I ++++ + + V A +D L E+ + + VTW K ++ ++F + + Sbjct: 10387 PRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMSQKRHLFS 10446 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYER--EYRIKRGSDVT 1306 L + T+ Y +A T +LK+ + PP V + R+K + Sbjct: 10447 LSLDAVTKLHAGNYGIHAANASGNTTAEIQLKILDIPGPPASVKLDEILSDRVKLSWEAP 10506 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAGIYKLRLEN 1364 L VD + P ++V+ + + + + S I + +++++ +++R EN Sbjct: 10507 L-VDGGS---PITNYVVDKRETSRAEWAQVSAKISRDTTECSVERLIEGHEYQFRVRAEN 10562 Query: 1365 NCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + G D ++ ++ + P P + I + + W EP + G S I+ Y+VE Sbjct: 10563 HYGTGDAIISEPVVARNPFTVPGACDPPVLTNITKEHMTVSWKEPSDDGKSPILGYLVEK 10622 Query: 1420 QEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E W I+ K + + + L + Y FR AVN+ + S+ + + Sbjct: 10623 RETKEVNWTKINRKPLLERTLEVGGLSEGAQYEFRVIAVNKAGLGKPSDPSNAASALDPL 10682 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELT 1502 P + K I T N I+LT Sbjct: 10683 YPPGPPISP--KAIDT-TNSTIKLT 10704 Score = 61.3 bits (142), Expect = 3e-07 Identities = 63/256 (24%), Positives = 108/256 (42%), Gaps = 18/256 (7%) Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 IK D D V C++K+N + + + G ++ +++K LD P Sbjct: 10838 IKTTDTDTLV---CVEKVNRYDAGKYILNLDSVSG----MKMYTVIVKV-LDTPGPPLNL 10889 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSI 1831 +S I W +GGS I Y V+ + E K W + +I+ L Sbjct: 10890 MIKET-SKDSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVTTSCTKTSFKIEDLEP 10948 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 +Y FR+ A+N+ G P + D + + P + +V T S TL W +P S Sbjct: 10949 GRSYCFRVLAQNQYGIGEPCETVDAVRASEQPGPVMDFKTLLV---TKDSCTLSWKKPIS 11005 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 +GGS I Y++E + K W +++ ++ +++ E E +R+ A N G P Sbjct: 11006 DGGSRIIAYVLEVLNGEDK-WKELLR--SKNMQYSAKDLVEGREYKYRVFATNDSGDG-P 11061 Query: 1952 TESQSVRLEKHATVPS 1967 + SV + +PS Sbjct: 11062 VKELSVLAKDINVLPS 11077 Score = 54.0 bits (124), Expect = 4e-05 Identities = 48/150 (32%), Positives = 78/150 (52%), Gaps = 16/150 (10%) Query: 692 CSVLKIT--NVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPP-QVIEPLKS--M 744 C L IT N+ + + V AVN GE S I + I+ E P + ++ KS + Sbjct: 6716 CKDLTITLENLTENMMFDFRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAI 6775 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKN----NKPVKALPTKSD---GDTHSITILKPKKV 797 IVR+G ++ + A++VG P PT W KN ++P +A+ +S+ T + I P+ V Sbjct: 6776 IVRKGAAIEIPAEIVGLPLPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESV 6835 Query: 798 K-DEGVYTLKAENSEGIAE-TSAVITVEEP 825 + D G+Y L A N+ G+ + T V ++ P Sbjct: 6836 RQDTGMYKLTATNTRGVGQRTMRVDILDRP 6865 Score = 52.0 bits (119), Expect = 2e-04 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 7/128 (5%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860 + +KA N G E S I+V +EN+ ++ F+ I V++ I++ A + P Sbjct: 6734 FRVKAVNEVGNGEPSKAISVNIQEDENSPTVKWMKFFKSDAIIVRKGAAIEIPAEIVGLP 6793 Query: 861 VPSITWYRNNEII-SPSETITQNFDGENIELVITNV----DSEIDSGDYKCVASNSAGKS 915 +P+ W +N +I P+E +T + N + + T + D+G YK A+N+ G Sbjct: 6794 LPTFEWTKNGVVIDQPTEAMTLESEEINRQTITTKIGIPESVRQDTGMYKLTATNTRGVG 6853 Query: 916 SHGARVTI 923 RV I Sbjct: 6854 QRTMRVDI 6861 Score = 51.6 bits (118), Expect = 2e-04 Identities = 84/425 (19%), Positives = 156/425 (36%), Gaps = 22/425 (5%) Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVI 1236 CEV + V P L + +++ A + L +I + VTW K + I Sbjct: 10772 CEVPEKHIAKDVFVT-PEAELDAELKDTLVLTAGSKMKLHAKIKGRPIPRVTWAKMNTNI 10830 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK---VEVVEFPPKIVDY 1293 +D + + + + + K D +Y + LD+ S K+ V+V++ P ++ Sbjct: 10831 KDRQGIIIKTTDTDTLVCVEKVNRYDAGKYI-LNLDSVSGMKMYTVIVKVLDTPGPPLNL 10889 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + K ++L D ++ +IV+ + ++ + + S I+ +E Sbjct: 10890 MIKETSK--DSASILWDEPLIDGGSEITGYIVDKRDAERKAWSNVTTSCTKTSFKIEDLE 10947 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNILEIDSSSINICWDEPENTG 1408 + +++ +N G + V + ++P P L + S + W +P + G Sbjct: 10948 PGRSYCFRVLAQNQYGIGEPCETVDAVRASEQPGPVMDFKTLLVTKDSCTLSWKKPISDG 11007 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 S II YV+E +W + Q S ++L Y++R +A N+ E + Sbjct: 11008 GSRIIAYVLEVLN-GEDKWKELLRSKNMQYSAKDLVEGREYKYRVFATNDSGDGPVKELS 11066 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--DGKKLKTAK 1526 K I + P N + ++ L G P P V+W + D T + Sbjct: 11067 VLAKDINVLP-SCDLRDLPNLNYIAKEGSNVRLKIPIIGKPTPAVSWKKGEDENLTDTGR 11125 Query: 1527 ATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583 E+ Y N G E++ V + KP I N IK K Sbjct: 11126 VCVESTAVNTTLLIRDCQRTDASKYTITLRNSAGTKESTIFVRVVGKP--GIPNGPIKFK 11183 Query: 1584 HKVGD 1588 D Sbjct: 11184 EVTAD 11188 Score = 50.8 bits (116), Expect = 4e-04 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 4/120 (3%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQV 533 DEN +Y + +NE + E+ + P F +K +H D G V+ E +V Sbjct: 763 DENTPGKYSCEVMNEDGSDICHALVTLGTERKIPPTFTKK-PSEHIEDAEGKLVKLESRV 821 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G + W++ I S + + + NVA + +R+ D+G +TC A N AG AS Sbjct: 822 SGSQPLSVIWYKDNKEINTSDIYDVSFKS-NVAVMCLRKATVTDSGVYTCSASNEAGTAS 880 Score = 49.6 bits (113), Expect = 0.001 Identities = 33/122 (27%), Positives = 56/122 (45%), Gaps = 5/122 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A NS G + + E E+ EP + + +T K +++ A V+ P P Sbjct: 9965 FRVAARNSMGSSLPTETREAYEIKEQMFEPKIIMTEL--VTAKAGAKLRVEALVSGKPAP 10022 Query: 863 SITWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 + W R N ++S S +N+ ++I S DSG+Y VA NS+GK ++ Sbjct: 10023 ACQWKRGENNVVSSSRLAVHK--SQNMCVLIIKDVSRQDSGEYSLVAENSSGKIEQTLKI 10080 Query: 922 TI 923 I Sbjct: 10081 II 10082 Score = 48.8 bits (111), Expect = 0.002 Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 8/109 (7%) Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPT 765 T V ++R E + PI++ + E PP++ ++ K + V+ G V L A+V G P P Sbjct: 10364 TAVNISRPSEITDPILV---SAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPK 10420 Query: 766 ITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSEG 812 +TW KN + +KA K H ++ K G Y + A N+ G Sbjct: 10421 VTWSKNGETLKADKEFKMSQKRHLFSLSLDAVTKLHAGNYGIHAANASG 10469 Score = 48.0 bits (109), Expect = 0.003 Identities = 24/100 (24%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 + + + P+F +K+ + G+ V+FEC++E P WF+ + IK S ++ Sbjct: 217 TRSEEVPPVFKKKICNMESNIGNPVKFECEIEETPNVTFKWFKAGSEIKQSDKVRI-ISR 275 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 ++L + +D+G ++C A N G + + +L + A Sbjct: 276 QTTSSLELPSPTKDDSGEYSCRASNKHGSDTCSAQLNITA 315 Score = 48.0 bits (109), Expect = 0.003 Identities = 38/125 (30%), Positives = 59/125 (47%), Gaps = 8/125 (6%) Query: 708 YTVVAVNREGEASLPIVLKIKT--GEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764 + V AVN G K T E EPP + ++ ++VR GES L + G P P Sbjct: 8027 FRVSAVNEVGPGKPSFSTKPITCKDELEPPTIELDFRDKVVVRVGESFALQGRYTGKPAP 8086 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE-TSAVI 820 +ITW +++K +KA + K+ T + I+K ++ G Y + EN G + VI Sbjct: 8087 SITWSRDDKELKADNHIKFKNTLTTMCLGIVKAQR-GHSGKYCVTVENCTGARKGICNVI 8145 Query: 821 TVEEP 825 + P Sbjct: 8146 VADRP 8150 Score = 47.6 bits (108), Expect = 0.004 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 6/131 (4%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 LK + KF+ + GE + + +K +T + + M++ G + + Sbjct: 7723 LKENALFKFRVIALNAAGLGEPGEVADALEMKDRTILPVLELDVSVKEKMVIHAGGVIRI 7782 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVYTLKAENSE 811 A V G P P ITW ++ PV P+++ +T SI+ ++K GVYT+ A+N Sbjct: 7783 LAYVSGQPPPVITWSRDEYPV---PSEAVIETTSISCSMVIKDCTRAQRGVYTITAKNDG 7839 Query: 812 GIAETSAVITV 822 G + S ++ V Sbjct: 7840 GEVKKSVIVEV 7850 Score = 45.2 bits (102), Expect = 0.020 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 11/136 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV---IEPLKSMIVRQG 749 ++T + + Q Y V AVNR G AS P + KEPP++ + L + R G Sbjct: 5009 QVTGLIEGQWYAYRVRAVNRLG-ASRPCKATDEILAVDPKEPPEIQLDAKLLAGLTARAG 5067 Query: 750 ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + L A V+G P P + W K + KP + + T HS + D Y ++ Sbjct: 5068 TKIDLPADVLGKPEPRVKWTKADLVLKPEERI-TIDTKPGHSTLSIANTTRSDTATYIIE 5126 Query: 807 AENSEGIAETSAVITV 822 A N+ G A + + + Sbjct: 5127 AVNTSGRATATVDVNI 5142 Score = 45.2 bits (102), Expect = 0.020 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 7/101 (6%) Query: 630 EGIPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 E +PP + K V GSD+ LE + P P + W GE + D+ ++ Sbjct: 10383 ENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKMS--Q 10440 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 H++ L + V K G Y + A N G + I LKI Sbjct: 10441 KRHLFS--LSLDAVTKLHAGNYGIHAANASGNTTAEIQLKI 10479 Score = 44.4 bits (100), Expect = 0.035 Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 5/131 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQV---IEPLKSMIVRQGESV 752 +T + + + V AVN G + + ++ E +E P V I +I+R GE++ Sbjct: 6430 VTGLTEGADYNLRVYAVNEGGHGAPGMTEPVQAKEPEEAPGVEFDISVRNGVIIRAGETL 6489 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAENSE 811 L A V G P P + W K+ + + S T+ K ++ D G+Y + N Sbjct: 6490 RLPAVVTGRPVPEVKWTKDGAEPDKEHVVIEAEIKSSTLSIKKALRTDHGIYQITGTNPS 6549 Query: 812 GIAETSAVITV 822 G S + V Sbjct: 6550 GTKSVSVKVDV 6560 Score = 44.4 bits (100), Expect = 0.035 Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 10/147 (6%) Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEP 740 I D+ +C+ ++ + + E + + A N+ G+ P L K+ PP+V Sbjct: 8999 INKDLIKFCA-FRVPGLNEGIEYRFRIKASNKVGDGE-PRELTETVLAKDILVPPEVTVD 9056 Query: 741 LKS---MIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKK 796 + + VR G+ + L +V G P P ITW K+ + + + T+ + + + ++ Sbjct: 9057 VACRDLLTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDA 9116 Query: 797 VK-DEGVYTLKAENSEGIAETSAVITV 822 V+ D G Y ++A+NS G A+ + ++ V Sbjct: 9117 VRADYGKYAIQAKNSSGQAQATIIVNV 9143 Score = 44.0 bits (99), Expect = 0.046 Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 4/123 (3%) Query: 803 YTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 + +K++N+ GI+ +TS IT +E T + + + + VK TI L A + P Sbjct: 8624 FRVKSQNAIGISRPDTSVPITCQEKTLAPTIE-VDVKLIEGLVVKAGSTILLPAVMLGIP 8682 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P+ W + +G + L I+ + DSG+Y SN AG S Sbjct: 8683 TPTAKWQSEGNELKTEGKFKIVTEGNSTTLTISEC-ARTDSGEYSLTVSNPAGSKSVALH 8741 Query: 921 VTI 923 VT+ Sbjct: 8742 VTV 8744 Score = 43.6 bits (98), Expect = 0.061 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGES 751 +T + + +E + V A N G + S L + +PPQV + +++GE Sbjct: 6003 VTGLTEGKEYQFRVRAENIAGASDPSRSTPLIMAADPVDPPQVTLFARIASGLSIKKGEE 6062 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTK 781 + L A + G+P PT+TW +N++ V+ P K Sbjct: 6063 IRLDAYISGSPYPTVTWLRNDENVRQPPAK 6092 Score = 43.6 bits (98), Expect = 0.061 Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 4/109 (3%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +TV+ I LV RV P P ITW ++ ++ + N + +ELVI + D Sbjct: 9063 LTVRAGQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEMNNNFPLVELVIQDA-VRADY 9121 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILE 949 G Y A NS+G++ A + ++V + ++L+ +Y T++ V E Sbjct: 9122 GKYAIQAKNSSGQAQ--ATIIVNVLDIPGACQNLKVAYVTKDSCMVSWE 9168 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/121 (22%), Positives = 57/121 (47%), Gaps = 6/121 (4%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 + V N GE++ ++ E+ +P ++ + +++V+ G++V + A+++G P+P Sbjct: 9318 FRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKPQPE 9377 Query: 766 ITWCKNNKP---VKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W K K L + + T+ + L + D G Y + A N+ G A + Sbjct: 9378 VKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEAKVN 9437 Query: 822 V 822 V Sbjct: 9438 V 9438 Score = 43.2 bits (97), Expect = 0.081 Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ ++ E V G P P W R + S ++ N+ L+I++V +D+G ++ Sbjct: 10007 GAKLRVEALVSGKPAPACQWKRGENNVVSSSRLAVH-KSQNMCVLIIKDVSRQDSGEYSL 10065 Query: 584 VAKNAAGFASSTTELIV 600 VA+N++G T ++I+ Sbjct: 10066 VAENSSGKIEQTLKIII 10082 Score = 41.9 bits (94), Expect = 0.19 Identities = 17/45 (37%), Positives = 27/45 (60%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 + KP PP K ++LEI +S + W +P G + I YV++Y E+ Sbjct: 9850 VSKPDPPQKVDVLEISKNSATVGWVKPMRDGGAKIDGYVIDYLEL 9894 Score = 41.5 bits (93), Expect = 0.25 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 10/149 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPI----VLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + I +K+ ++ + V A N G +SLP +IK EP ++ L + + G Sbjct: 9952 ISIAGLKEGRKYRFRVAARNSMG-SSLPTETREAYEIKEQMFEPKIIMTEL--VTAKAGA 10008 Query: 751 SVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + + A V G P P W + NN + + I+K +D G Y+L AE Sbjct: 10009 KLRVEALVSGKPAPACQWKRGENNVVSSSRLAVHKSQNMCVLIIKDVSRQDSGEYSLVAE 10068 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFIN 837 NS G E + I + + EPP I+ Sbjct: 10069 NSSGKIEQTLKIIIRD-IPGPPEPPFEIS 10096 Score = 41.1 bits (92), Expect = 0.33 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 GS+ FECQ+ P IT W + + I+ S + + D L I +V D G +T Sbjct: 2676 GSSAVFECQIS--PSTAITTWMKDGSNIRESPKHK-FTSDGKDRKLQIIDVQLSDTGEYT 2732 Query: 583 CVAKNAAGFASSTTELIVE 601 CVAK +ST +L+VE Sbjct: 2733 CVAKLGNKEKTSTAKLVVE 2751 Score = 41.1 bits (92), Expect = 0.33 Identities = 29/124 (23%), Positives = 52/124 (41%), Gaps = 2/124 (1%) Query: 802 VYTLKAENSEGIAETSAVITVEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 +Y + + E++ V T E EE +P L + + VK + + A + P Sbjct: 9315 IYQFRVQTKNEGGESNWVTTAEVLVKEELVQPELKVKMVGTLVVKAGDAVSIEAELLGKP 9374 Query: 861 VPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P + W + + S+ + Q G N + + D+G Y A+N+AG S A Sbjct: 9375 QPEVKWSKEGDTRDISKGLRVQVETGTNFTKLQLSNSRRGDTGKYIITATNAAGTCSAEA 9434 Query: 920 RVTI 923 +V + Sbjct: 9435 KVNV 9438 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/99 (26%), Positives = 52/99 (52%), Gaps = 7/99 (7%) Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA---VITVEEPTEENAEP 832 + +P G ++++T L K E + ++AEN G ++ S +I +P + + Sbjct: 5990 RCVPNLVPGFSYTVTGLTEGK---EYQFRVRAENIAGASDPSRSTPLIMAADPVDP-PQV 6045 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 LF +++K+ I+L A ++ +P P++TW RN+E Sbjct: 6046 TLFARIASGLSIKKGEEIRLDAYISGSPYPTVTWLRNDE 6084 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 2/112 (1%) Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 Y K GS+V L + P P W + + + + +L I+ + TDA Sbjct: 11088 YIAKEGSNVRLKIPIIGKPTPAVSWKKGEDENLTDTGRVCVESTAVNTTLLIRDCQRTDA 11147 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPEN 1406 Y + L N+ G + + V ++ KP P P E+ + + W P++ Sbjct: 11148 SKYTITLRNSAGTKESTIFVRVVGKPGIPNGPIKFKEVTADGATLKWSAPKD 11199 Score = 39.1 bits (87), Expect = 1.3 Identities = 41/168 (24%), Positives = 65/168 (38%), Gaps = 9/168 (5%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G+ I L ++ PEP + W + P+E I++ D S L I N + T Sbjct: 5067 GTKIDLPADVLGKPEPRVKWTKADLVLKPEERITI----DTKPGHSTLSIANTTRSDTAT 5122 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y + AVN G A+ + + I + PP + S I + + +A P Sbjct: 5123 YIIEAVNTSGRATATVDVNI-LDKPGPPAAFD--ISEITNESCCLAWNAPRDDGGSPVAN 5179 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGI 813 + +P + T T K K+ E V+ + AEN GI Sbjct: 5180 YIVEMRPTDKEEWQKLSATIKQTAFKATKLVPLKEYVFRVSAENQYGI 5227 Score = 39.1 bits (87), Expect = 1.3 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + +V+G P P+ITW + ++ + +M ++ + LVI++ D G + Sbjct: 9068 GQIINLVTRVKGRPDPEITWTKDARVLGRDKRTEM-NNNFPLVELVIQDAVRADYGKYAI 9126 Query: 584 VAKNAAGFASST 595 AKN++G A +T Sbjct: 9127 QAKNSSGQAQAT 9138 Score = 39.1 bits (87), Expect = 1.3 Identities = 50/226 (22%), Positives = 91/226 (40%), Gaps = 22/226 (9%) Query: 705 EGTYTVVAVNREGEASLP-----IVLKIKTGEKEPPQVIEPLKSMIV-------RQGESV 752 E T+ V A+NR G+ I + P+V++ K+ + G S Sbjct: 10255 EYTFRVSAINRAGQGKPSKKTDFITARTPVDAPGKPEVLDVTKNAVSLVWTKPKNDGGSK 10314 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 I+ V P TW + N + +P + ++ T L+ V A N Sbjct: 10315 IIGYYVEAMRLPGDTWVRCNTSSQNVPREE----YTATGLEEGANYQFRVIAKTAVNISR 10370 Query: 813 IAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 +E + I V + EN P L + + + VK + L A V P+P +TW +N Sbjct: 10371 PSEITDPILV---SAENVPPRIELSVQMKKMLPVKAGSDVCLEAEVFGKPMPKVTWSKNG 10427 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 E + + + L + V +++ +G+Y A+N++G ++ Sbjct: 10428 ETLKADKEFKMSQKRHLFSLSLDAV-TKLHAGNYGIHAANASGNTT 10472 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V E +V G P P++TW + +K ++F+M ++ +L + V AG + Sbjct: 10404 GSDVCLEAEVFGKPMPKVTWSKNGETLKADKEFKM-SQKRHLFSLSLDAVTKLHAGNYGI 10462 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 A NA+G ++ +L I++ P Sbjct: 10463 HAANASGNTTAEIQLKILDIP 10483 Score = 38.7 bits (86), Expect = 1.7 Identities = 39/174 (22%), Positives = 70/174 (40%), Gaps = 12/174 (6%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V GS ILL ++ IP P W +G E+ + + E + + L I+ + Sbjct: 8666 VKAGSTILLPAVMLGIPTPTAKWQSEGNELKTEGKFKIVTEGN----STTLTISECARTD 8721 Query: 705 EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 G Y++ N G S+ + VL + + P ++E ++ Q + G+ Sbjct: 8722 SGEYSLTVSNPAGSKSVALHVTVLDVPSAPVGPVNILEVTPDHMIIQWRA---PKDDGGS 8778 Query: 762 PRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 P + K + KP + S G T + + + E + ++AEN GI Sbjct: 8779 PLMSYVVEKKDVKKPWEPWSVVSSGSTSTKAKVPRLEKGREYIVRVRAENKIGI 8832 Score = 37.5 bits (83), Expect = 4.0 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 16/146 (10%) Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 VKA + G IT LK + V L N+ G+ E V E + P L Sbjct: 7706 VKAKDKEVRGTKFVITGLKENALFKFRVIAL---NAAGLGEPGEVADALEMKDRTILPVL 7762 Query: 835 FINRFQEITVKEK------GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888 + +++VKEK G I+++A V+ P P ITW R +E PSE + + + Sbjct: 7763 EL----DVSVKEKMVIHAGGVIRILAYVSGQPPPVITWSR-DEYPVPSEAVIET-TSISC 7816 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGK 914 +VI + + G Y A N G+ Sbjct: 7817 SMVIKDC-TRAQRGVYTITAKNDGGE 7841 Score = 37.5 bits (83), Expect = 4.0 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G + +E L+ P+P++ W +G+ + + V +E+ + + L+++N ++ Sbjct: 9358 VKAGDAVSIEAELLGKPQPEVKWSKEGDTRDISKGLRVQVETGTNF--TKLQLSNSRRGD 9415 Query: 705 EGTYTVVAVNREGEAS 720 G Y + A N G S Sbjct: 9416 TGKYIITATNAAGTCS 9431 Score = 37.1 bits (82), Expect = 5.3 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ + V G P P++ W + ++KP + + + +TL I D T+ Sbjct: 5067 GTKIDLPADVLGKPEPRVKWTKADLVLKPEERITIDTKPGH-STLSIANTTRSDTATYII 5125 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 A N +G A++T ++ I++ P Sbjct: 5126 EAVNTSGRATATVDVNILDKP 5146 Score = 37.1 bits (82), Expect = 5.3 Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800 ++++ G + L A++ G P P +TW K N +K T + T++ +KV D Sbjct: 10798 TLVLTAGSKMKLHAKIKGRPIPRVTWAKMNTNIKDRQGIIIKTTDTDTLVCVEKVNRYDA 10857 Query: 801 GVYTLKAENSEGIAETSAVITV 822 G Y L ++ G+ + ++ V Sbjct: 10858 GKYILNLDSVSGMKMYTVIVKV 10879 Score = 36.7 bits (81), Expect = 7.0 Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 18/187 (9%) Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP-KKVKDEGVYTL 805 R G S I V + W + N P K + T S +++ LK KK + V Sbjct: 7097 RDGGSPIKGYIVEVQDEGSHEWKRINTPDKLILTNS----YTVPGLKENKKCRFRIVAVN 7152 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGT-IKLVARVTRNPVPS 863 A SE TS +I V++ EE P + I+ QE+ GT +K+ A ++ P+P+ Sbjct: 7153 AAGESEPSPRTSDII-VQDILEE---PVITIDVTSQELLNCRAGTTLKIPATISGKPLPN 7208 Query: 864 ITWYRNNEIISPSET------ITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSS 916 +TW + S + + + + V+T +S++ SG Y A+N AG Sbjct: 7209 VTWEFDGTAPSEKKNERHTLPVDSDISSSDTTSVVTIPESKLHHSGRYIITANNQAGTKI 7268 Query: 917 HGARVTI 923 RV + Sbjct: 7269 VKVRVNV 7275 Score = 36.3 bits (80), Expect = 9.2 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 4/91 (4%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P + + ++V +GE + + P+P++ W K + +K L + + + + Sbjct: 5749 PTIDVATQDIVVVEGEKMDIKIPYRAIPKPSMVWKKGDTELKTEDRLTLTCELNRVHLEL 5808 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 LK K +D GVYT+ ENS G + +TV Sbjct: 5809 LKCKH-EDAGVYTVTLENSLGSVTGTVSVTV 5838 Score = 36.3 bits (80), Expect = 9.2 Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 +W +G+E++ ++ +G L I +C D+GEYS V N Sbjct: 8687 KWQSEGNELKTEGKFKIVTEGNSTTLTISECARTDSGEYSLTVSN 8731 >UniRef50_Q8WZ42 Cluster: Titin; n=65; Eukaryota|Rep: Titin - Homo sapiens (Human) Length = 34350 Score = 299 bits (733), Expect = 7e-79 Identities = 200/685 (29%), Positives = 321/685 (46%), Gaps = 41/685 (5%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKV 1350 D + ++ G + L V + P P W + ++ + +D KS T + Sbjct: 20625 DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRD----RIGLDIKSTDFDTFLRC 20680 Query: 1351 ENT---DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 EN DAG Y L LEN+CG + + V +LD P PP + EI S + W+ P Sbjct: 20681 ENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIID 20740 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 G S II YVV+ ++ + W +V +KT + NL+ SY FR +A NE I D E Sbjct: 20741 GGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGE 20800 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITT--------EPNEDIELTCIFGGVPQPKVTWYRD 1518 T + +K ++ P V+ +++++ +P+ D + I G V + Sbjct: 20801 TRD---AVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGG-SRIIGYVVDFLTEENKW 20856 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 + +K+ Y + ++ A N++GE S + + + V+ + Sbjct: 20857 QRVMKSLSLQYSAKDLTEGKEYT------FRVSAENENGEGTPSEITVVARDDVVAPDLD 20910 Query: 1579 -----DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 D+ K + + I+G P P V W K + L D ++ + + + + Sbjct: 20911 LKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVY 20970 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 + ++S + KYTI N AGT +++KV KP P GP+ E++ E++T++W PP DD Sbjct: 20971 DCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDD 21030 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEAL 1753 GG E+T Y +EK + NN+W+ A + T+ + +L+E EY FRV A+N G E L Sbjct: 21031 GGSEITNYILEKRDSVNNKWVTCASAVQKT-TFRVTRLHEGMEYTFRVSAENKYGVGEGL 21089 Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812 +SEPIV + DVP + ++SV +TW +K GGSPI Y +E K+ Sbjct: 21090 KSEPIVARHPFDVPD-APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 21148 Query: 1813 WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 WK ++ L+ Y+FR+ A N G P + + + PP +P Sbjct: 21149 WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPE 21208 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 V T SVTL WTEP+ +GG +T YI+E + + KSW K V + ++ Sbjct: 21209 ---VINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDL 21265 Query: 1931 KEKDEIIFRISAENTVG-VSLPTES 1954 E + FRI A+NT G +S P+ES Sbjct: 21266 VEGGKYEFRIRAKNTAGAISAPSES 21290 Score = 290 bits (711), Expect = 3e-76 Identities = 346/1472 (23%), Positives = 590/1472 (40%), Gaps = 117/1472 (7%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+K V E I L C V+ P ++ W EEI+ + E +L Sbjct: 13392 FTKNLANIEVSETDTIKLVCE-VSKPGAEVIWYKGDEEIIETGRYEILTEGRKR----IL 13446 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I N G Y + + K+K E + +P +++ + +GE Sbjct: 13447 VIQNAHLEDAGNYNCRLPSSRTDG------KVKVHELAAEFISKP-QNLEILEGEKAEFV 13499 Query: 756 AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + P + W +++K +++ +DG + ++K ++D G Y + G Sbjct: 13500 CSISKESFP-VQWKRDDKTLESGDKYDVIADGKKR-VLVVKDATLQDMGTYVVMV----G 13553 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A +A +TV E + ++ VKE+ + V + W+RN E Sbjct: 13554 AARAAAHLTVIEKLR-------IVVPLKDTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEA 13605 Query: 873 ISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVT 929 I S I Q + + ++D D +Y +N G++ A + ++ E + Sbjct: 13606 IFDSSKYIILQKDLVYTLRIRDAHLD---DQANYNVSLTNHRGENVKSAANLIVEEEDLR 13662 Query: 930 FVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 V+ L K ET E K+V C+ + V+ KW N +E+ D+R + + Sbjct: 13663 IVEPL-KDIETMEKKSVTFWCKVNRLNVTLKWTKNGEEVP-FDNRVSYRVDKYKHMLTIK 13720 Query: 989 XXXX-DVG-VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D G I +D+ + +L++ E EF+ L+D V E D A+ +++ E A+ Sbjct: 13721 DCGFPDEGEYIVTAGQDKSVAELLII-EAPTEFVEHLEDQTVTEFDDAVFSCQLSREKAN 13779 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 V W R+G IK K KY FEK G I +L I++ + DE EY+C + D A + V E+P Sbjct: 13780 VKWYRNGREIKEGK-KYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIP 13838 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 EII Q+ G F EL K V+W ++ + + Q+ +GK +L+I Sbjct: 13839 VEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQIC 13898 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL- 1225 D D GEY + + A L + ++ + LV + LT+ +P + Sbjct: 13899 DIKPRDQGEYRFIAKDKEARAKLELAAAP---KIKTADQDLV-VDVGKPLTMVVPYDAYP 13954 Query: 1226 --DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281 + W+K+ E T+ + ++ + I + + D+ Y VL + K+ + + Sbjct: 13955 KAEAEWFKEN---EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINL 14011 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND--EWIVNSKIIKKCKHTKPSID 1339 +V++ P + + E +V+L + + ++V + IK+ + Sbjct: 14012 KVIDVPGPVRNLEVTETFD--GEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDR 14069 Query: 1340 SKSASLTIKKVENTDAG-IYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEI 1392 ++S T+ ++ ++++ N G + VE + + D P PP I ++ Sbjct: 14070 AESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDV 14129 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450 + +++ W+ PE G + I YV+E ++ + W + + S + ++ Y Sbjct: 14130 NRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS 14189 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE-DIELTCIFGGVP 1509 FR A N + + S T + KV + SP V + T + E GG P Sbjct: 14190 FRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSP 14249 Query: 1510 ----------QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 + K W R KL + TY+ Y+ A N G Sbjct: 14250 ILGYIIERCEEGKDNWIRCNMKL-VPELTYK------VTGLEKGNKYLYRVSAENKAGVS 14302 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE------GIPPPEVIWYKNGNKL 1613 + S ++G + K G E +V I G P P W L Sbjct: 14303 DPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVL 14362 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 E + T + + I +RS YT++ N T S E+ + V +PS P+ + Sbjct: 14363 ETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPK-EL 14421 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733 +I+++SV + W+PP DDGG LT Y +EK E W KV D D+E + + L + Sbjct: 14422 KFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLE-FTVPDLVQ 14480 Query: 1734 NCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 EY+F+V A+N G E A EP+ + T VP N S+++TW P + Sbjct: 14481 GKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTAN-SIFLTWDPPK 14539 Query: 1793 KNGGSPIIDYKVEIKQEGK-KWKX-XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 +GGS I Y VE G KW + L Y +R+ A N G S P Sbjct: 14540 NDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKP 14599 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 ++I T P + + + K P + G P E K Sbjct: 14600 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP------EPKI---- 14649 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV----- 1965 +WTK + IEN+ +K + S + G + E+ +V A V Sbjct: 14650 TWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYI-IEAVNVCGRATAVVEVNVL 14708 Query: 1966 --PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 P PP A +I V + + +W P DGG+ + Y + R +W ++ V Sbjct: 14709 DKPGPPAA-FDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSST-VKD 14766 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 F L N Y+ R+ A N G+ EP+++ Sbjct: 14767 TNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 14798 Score = 283 bits (695), Expect = 3e-74 Identities = 321/1444 (22%), Positives = 574/1444 (39%), Gaps = 102/1444 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G +C L + + + W KG+++ P + + E +H L + +VK Sbjct: 13134 VTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSDKVVPRSEGKVH----TLTLRDVKLED 13188 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPR 763 G + A + + A+L + KEPP + +PL+ V +G + +L +V Sbjct: 13189 AGEVQLTAKDFKTHANLFV--------KEPPVEFTKPLEDQTVEEGATAVLECEV-SREN 13239 Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITI--LKPKKVKDEGVYTLKAENSEGIAETSA 818 + W KN + K +DG + I P+ +K YT A++ + TS Sbjct: 13240 AKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIK---TYTCDAKDFK----TSC 13292 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V P E F+ ++ V+EK + ++R + W+++ I + Sbjct: 13293 NLNVVPPHVE------FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKK 13345 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 G + +++ N D +Y C + ++S +T+ E+ F K+L + Sbjct: 13346 YDIISKGA-VRILVINKCLLDDEAEYSCEVRTA--RTS--GMLTVLEEEAVFTKNLA-NI 13399 Query: 939 ETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 E E T+ L C+ S WY +EI EI+ EGR D G Sbjct: 13400 EVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNY 13459 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 C + T + V E EFI K Q+ E+ E + A I+ E+ V W+RD + ++ Sbjct: 13460 NCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESFPVQWKRDDKTLE 13519 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 +KYD G R L +++ ++ D G Y ++ A +TV+E I+ L++ + Sbjct: 13520 -SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE-KLRIVVPLKDTR 13577 Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 V + + F E+ A +WF++ I S+ + L+I D LDD Y+ Sbjct: 13578 VKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYN 13637 Query: 1178 CEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 + N K A L VEE + L + + + + ++ + + W K Sbjct: 13638 VSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWC-KVNRLNVTLKWTKN 13696 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292 + + + D K L I+ C D+ EY KS +L + +E P + V+ Sbjct: 13697 GEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLI--IEAPTEFVE 13754 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 + + + D + N +W N + IK+ K K D L IK Sbjct: 13755 HLEDQTVTEFDDAVFSCQLSR-EKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRL 13813 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 D Y +E+ A + + ++ PP +ILE + + + ++ Sbjct: 13814 DDECEYACGVEDRKSRARLFVEEIPVEIIRPP--QDILEAPGADVVFLAELNKDKVEVQW 13871 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 + + + D + +S I + Q + YRF I+ E + Sbjct: 13872 LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRF---------IAKDKEARAKLE 13922 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-TYEN 1531 + KI++ +++ + + + + + P+ + W+++ + L T T Sbjct: 13923 LAAAPKIKTAD-----QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAE 13977 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDE 1589 + YK + N HG+ E + + P + N ++ + +V Sbjct: 13978 QTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPG-PVRNLEVTETFDGEVSLA 14036 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSK-YTIEA 1647 W G ++I Y + K + + T S + L++ + + A Sbjct: 14037 WEEPLTDGG---SKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSA 14093 Query: 1648 SNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 N GT VE V YD P P V + +++R V++ W+PP DGG E+T Y Sbjct: 14094 RNRVGTGEPVETDNPVEARSKYDVPGPPLN-VTITDVNRFGVSLTWEPPEYDGGAEITNY 14152 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-I 1760 IE + + RW V + + + + E EY FRV AQN +G + + P V + Sbjct: 14153 VIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKV 14212 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXX 1817 ++ PS + SV + W P K+GGSPI+ Y +E +EGK W Sbjct: 14213 ADPIERPSPPVNLTSSDQTQS-SVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMK 14271 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSE 1876 ++ L Y +R+ A N+ G S P +T P+ + F Sbjct: 14272 LVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGL 14331 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936 + P + P + K ++ K+ T+ + E I + D+ Sbjct: 14332 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTL-SAYAELVISPSERSDKG 14390 Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDG 1994 I+ + EN V +++ E V + P+AP E++ + + V +W P+ DG Sbjct: 14391 IYTLKLENRV--------KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDG 14442 Query: 1995 GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 G+PL GY + R+V++ W +V V L+F + DL + Y+ ++ ARN+ G EP Sbjct: 14443 GSPLTGYVVEKREVSRKTWTKVMDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAY 14501 Query: 2055 SDEP 2058 DEP Sbjct: 14502 VDEP 14505 Score = 276 bits (676), Expect = 6e-72 Identities = 202/711 (28%), Positives = 312/711 (43%), Gaps = 35/711 (4%) Query: 1287 PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-- 1341 PP+++ + RE IK G + L + P P W K + TK ID Sbjct: 18142 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTW----KKEDRDAPTKARIDVTPV 18197 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 + L I+ + D GIY L +EN G V + V +LDKP PP + EI S + W Sbjct: 18198 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTW 18257 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVD 1460 EP + G S I YVVE +++ + +W + +K ++ ++L + Y FR A N+ Sbjct: 18258 KEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 18317 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVPQPK--VT 1514 ET + K + + P K L ++ + E + L GG P V Sbjct: 18318 RGPFVETPKPIKALDP--LHPPGPPKDLHHVDVDKTE-VSLVWNKPDRDGGSPITGYLVE 18374 Query: 1515 WYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 + +G + T N K G +T+ + Q+K V Sbjct: 18375 YQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVP 18434 Query: 1574 TISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 D+K K G A+I G+P P W +G++++ D+ Y + T +SV Sbjct: 18435 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 18494 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689 + IK R + +Y I SN AG+ +V V L V D P P GP+ + +++ E +TI W+P Sbjct: 18495 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 18554 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 P DDGG + Y +EK + + W V+ + I L + CEY+FRV A+N +G Sbjct: 18555 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLK-IPHLQKGCEYVFRVRAENKIGV 18613 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809 L+S P V K PS +N + ++W + +GGSPI Y +E ++ Sbjct: 18614 GPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT-VSWTLPKSDGGSPITGYYMERREV 18672 Query: 1810 GKKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 KW R+ L TY+FR++A N G S P S D I + + PP Sbjct: 18673 TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPG 18732 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC- 1926 P N + + + + L WT+P S+GGSPI Y++E + W +I + C Sbjct: 18733 PPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINK--DELIRQCA 18790 Query: 1927 --IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + + E +E FRI A N VG P E + K + PP L++ Sbjct: 18791 FRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAK--DILHPPEVELDV 18839 Score = 267 bits (654), Expect = 3e-69 Identities = 275/1199 (22%), Positives = 476/1199 (39%), Gaps = 92/1199 (7%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ + P F KL+ H G V FEC++ G Q++W++ ++K + Q + Sbjct: 8037 KERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF-VH 8095 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 NVATL I + G + C A N G ASS+ +LI LS+H Sbjct: 8096 NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLI----LSEH---------------- 8135 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +PP F KP + + G +C + I W EI P N + Sbjct: 8136 -------EVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 8188 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK- 742 + + + L + V K G YT A N G+ S L G +EPP+ I+ L+ Sbjct: 8189 LVEN----TATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHL----GVQEPPRFIKKLEP 8240 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--KVKDE 800 S IV+Q E ++ G+P + W K+ ++ S+ +L+ V+D Sbjct: 8241 SRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDS 8300 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 G YT +A N+ G A +S + V+ EPP+F + I + + L + P Sbjct: 8301 GDYTCEAHNAAGSASSSTSLKVK-------EPPIFRKKPHPIETLKGADVHLECELQGTP 8353 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 ++WY++ + + + + I NVD+ D G+Y+C A+N G + Sbjct: 8354 PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDA-ADIGEYQCKATNDVGSDTCVGS 8412 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEI-SGMDHREIIQ 977 + + FVK L T GK V L+ + + +S W+ +K EI D+ I Sbjct: 8413 IALKAPP-RFVKKL-SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 8470 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 + G C +K+ QE L V E + K + +V D Sbjct: 8471 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP-ATIVEKPESIKVTTGDT 8529 Query: 1034 AILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 LE + + W +DG+ + NKY + L I N + D G YS ++ Sbjct: 8530 CTLECTVAGTPELSTKWFKDGKEL-TSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 8588 Query: 1093 D----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE 1145 + +SCTA + V + +PP +L+ G+ E ++ + V WF +G+E Sbjct: 8589 NPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNE 8648 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201 I Q T+ L + + D+G+Y+C G+ +C+A LTV EP Sbjct: 8649 ISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKP 8708 Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 P +L N + ++ V+W+K S + ++ + + L + Sbjct: 8709 DPMDVLTGTNV-TFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTS 8767 Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 EYTC++ + + ++ P K V +Y I++G + L + P + Sbjct: 8768 QSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 8827 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W N + + + KSA L I DAG Y +EN G + IL+ Sbjct: 8828 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 8887 Query: 1381 P--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQ 1437 P +P + + S+ C + T + +Y + + TT + + +N T Sbjct: 8888 PYFVKQLEPVKVSVGDSASLQC--QLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 + N S + A N V + S +T + ++E K+ P+ + L+++ Sbjct: 8946 V-FNQVDINDSGEYICKAENSV--GEVSAST--FLTVQEQKL-PPSFSRQLRDVQETVGL 8999 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + C G V+WY+DGK LK + + +N Y C A Sbjct: 9000 PVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 9059 Query: 1554 NDHGEVETSCVVGI---QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 N G +S + + + P I + VG+ + G P +V W K+ Sbjct: 9060 NPIGSASSSARLILTEGKNPPFFDIRLAPVDA--VVGESADFECHVTGTQPIKVSWAKDS 9117 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 ++ + +Y I+ E ++ + + ++ + S +YT A N G S L + ++ P Sbjct: 9118 REIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPP 9176 Score = 262 bits (643), Expect = 6e-68 Identities = 222/868 (25%), Positives = 365/868 (42%), Gaps = 58/868 (6%) Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287 TW V+E ++ + + L+I D+ YT L + T +++V Sbjct: 14354 TWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIA 14413 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDS 1340 E ++ D+T + + P+D+ ++V + + + TK Sbjct: 14414 RPSAPKELKF-----GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV 14468 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCG-----HADVEMNV-TILDKPSPPGKPNILEIDS 1394 T+ + ++K+ N CG + D +N+ T P PP + + Sbjct: 14469 TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTA 14528 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRA 1453 +SI + WD P+N G S I Y+VE + +W++ + + +T+ + L+ Y +R Sbjct: 14529 NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRV 14588 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPK 1512 A+N S S TE + + + ++ K L +T + IEL G P+PK Sbjct: 14589 KALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPK 14648 Query: 1513 VTWYRDGKKLKTAK-ATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 +TW + LK K T EN + Y A N G V + Sbjct: 14649 ITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVL 14708 Query: 1569 QKP-------VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 KP + ++NE G + V+E +W+K + +++ Sbjct: 14709 DKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD-- 14766 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPV 1673 T + T +I KE + + A N G + +T K P P + Sbjct: 14767 ----TNFKATKLIPNKEY------IFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRL 14816 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733 +I++++VT+ W P DDGG +T Y +E+ +PD ++W++ + TY ++ L Sbjct: 14817 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 14876 Query: 1734 NCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 +Y FRV+A+N G + +S EPI+IK +D P + SV + W E Sbjct: 14877 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPID-PPWPPGKPTVKDVGKTSVRLNWTKPE 14935 Query: 1793 KNGGSPIIDYKVEIKQEG-KKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 +GG+ I Y +E+ + G +W + + L Y FR+ A N+ G S P Sbjct: 14936 HDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEP 14995 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 D + + L PPS PR V T + LKWT PE +GGSPITNYI+E + V+ K Sbjct: 14996 SEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK 15055 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPP 1969 W + T + + + E +FR++AEN +G S TE + L K T P PP Sbjct: 15056 GWQTVDTTVKDT-KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPP 15114 Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029 A L + V V W P+ DGG P+ Y I ++ T W++ GK F + Sbjct: 15115 YA-LAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVT 15173 Query: 2030 DLSENHTYMIRIYARNEIGLSEPLESDE 2057 D+ E ++ A NE G+ P E E Sbjct: 15174 DVIEGTEVQFQVRAENEAGVGHPSEPTE 15201 Score = 261 bits (640), Expect = 1e-67 Identities = 260/1070 (24%), Positives = 452/1070 (42%), Gaps = 66/1070 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+F+++ K G + L CRL + W G + DEN+ + ++ Sbjct: 7100 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNV--- 7156 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + LKI G Y+ A N G AS L + +K P I+P+ S+ V GES Sbjct: 7157 -ATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV-SIDVIAGES 7214 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V G ITW K+NK ++ G+T + ILK K D G YT +A Sbjct: 7215 ADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK-GDSGQYTCQAT 7273 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867 N G SA ++V+ EPP F+ + + V ++G +I+L +++ +P ++W+ Sbjct: 7274 NDVGKDMCSAQLSVK-------EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF 7326 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 RN+ + S +F ++ L+ N S DSGDY C A N G +S +T+ Sbjct: 7327 RNDSELHESWKYNMSFI-NSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 7385 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 V K +G VIL+C+ S T W ++K++ +I + Sbjct: 7386 VFTQK--PSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443 Query: 986 XXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 DVG C ++ +T + V + P F++KL D D L + Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEG 7503 Query: 1043 -ETADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----C 1096 + VVW +D GE+I+ +N +I L + + + G+Y C +++++ C Sbjct: 7504 FQPISVVWLKDRGEVIRESENT-RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMREC 7562 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 +A +TV+E P II + + V GN E +T L +WFKDG E+ + +T Sbjct: 7563 SAVLTVLE-PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHIT 7621 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEFILVPANTD 1213 K LKI ++ D G YS EV NS + TV S++ + R+ P FI + + Sbjct: 7622 FINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTV---SVHVSDRIVPPSFIRKLKDVN 7678 Query: 1214 AYLTVEIPDE-------TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 A L + E + V W++ + I K TL + D Y Sbjct: 7679 AILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIY 7738 Query: 1267 TCVLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 TCV + + + V V+ PP + G +T + P +W S Sbjct: 7739 TCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS 7798 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 + + + S++ L + +V+ ++G Y + N+ G A ++ + + + Sbjct: 7799 RELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVK 7858 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444 + +++ S + E TG I + ++ + I +E S+ +T+ T ++ L+ Sbjct: 7859 RLADFSVETGSPIVL--EATYTGTPPISVSWIKDEYLISQSERCSI-TMTEKSTILEILE 7915 Query: 1445 -TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 T Y + + D E + ++ P +PL+++ E L C Sbjct: 7916 STIEDYAQYSCLIENEAGQDICEAL-------VSVLEPPYFIEPLEHVEAVIGEPATLQC 7968 Query: 1504 IFGGVPQPKVTWYRDGKKLKTA---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 G P+ +++WY++ KL++A K ++N Y C A N G V Sbjct: 7969 KVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAV 8028 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 +S V+ I+++ + +K H+ +G I G P +V WYK+G L++D Sbjct: 8029 ASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDAN 8088 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLKVYDKP 1666 + + ++I + +SH +Y ASN GT SS ++ L ++ P Sbjct: 8089 LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVP 8138 Score = 261 bits (640), Expect = 1e-67 Identities = 196/695 (28%), Positives = 303/695 (43%), Gaps = 41/695 (5%) Query: 1282 EVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP-SI 1338 E +E P +D E + I+ G + L V + P P +W K+ + + + Sbjct: 23862 EKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDV 23918 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 S SL + V D+G Y L LEN+ G + V +LD PSPP + EI S++ Sbjct: 23919 TSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVS 23978 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457 I W+ P G S I Y+VE +E + +V N K I L+ SY FR A N Sbjct: 23979 ITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAEN 24038 Query: 1458 EVDISDASETTEYYKVIKETKIQSP-TVEKPLKNIT----TEPNEDIELTCIFGGVP-QP 1511 E I ++T + KV + + TV+ +N T+P D I V Q Sbjct: 24039 EYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQA 24098 Query: 1512 KVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-SCVVGIQQ 1569 K + + + ++K+ +A N ++ +A N+ G + S V I Sbjct: 24099 KHSEKWSECARVKSLQAVITN--------LTQGEEYLFRVVAVNEKGRSDPRSLAVPIVA 24150 Query: 1570 KPVITISNEDIKQKH-----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 K ++ D+K +VG + + I G P P + W K+G L+ N+T Sbjct: 24151 KDLVI--EPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDS 24208 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 + + IKE + +Y I +N G + + + DKP P+GPV ++S ES+T Sbjct: 24209 LDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESIT 24268 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 + W PPL GG ++T Y ++K + W + A V R T + KL EY FR+ A Sbjct: 24269 LSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVAR--TTLKVTKLKTGTEYQFRIFA 24326 Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 +N G S ALES+PIV + P I +S+ I W NGGSP+I Y Sbjct: 24327 ENRYGQSFALESDPIVAQYPYKEPG-PPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYH 24385 Query: 1804 VEIKQEGK-KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 +E K+ W + Q L Y+FR+YA N +G + + Sbjct: 24386 LERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVAR 24445 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 PP P +V + +TL+WT+P +GGS IT YI+E + + W K Sbjct: 24446 DPCDPPGTPEPIMVKRN---EITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNV 24502 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVG-VSLPTES 1954 + + + E FR+ A+N G +S P++S Sbjct: 24503 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDS 24537 Score = 256 bits (628), Expect = 4e-66 Identities = 263/1191 (22%), Positives = 485/1191 (40%), Gaps = 95/1191 (7%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ + P F+ KL+ + G++V EC+V G + WF+ I Q + + N Sbjct: 7663 DRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE-N 7721 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 V TL + + P D G +TCVA N AG + L V+ P S + +V Sbjct: 7722 VCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSV----------- 7770 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 ++L G+ TF+ V G+ P + W E+VP E+ ++++ Sbjct: 7771 --EVLPGMSLTFTS------VIRGT-----------PPFKVKWFKGSRELVPGESCNISL 7811 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E + + L++ V+ + G Y+ + N G AS L + KEP ++ L Sbjct: 7812 ED----FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV----KEPATFVKRLADF 7863 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGV 802 V G ++L A G P +++W K+ + S T TIL+ ++D Sbjct: 7864 SVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQ 7923 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y+ EN G A+++V EPP FI + + L +V P Sbjct: 7924 YSCLIENEAGQDICEALVSV-------LEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI 7976 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 I+WY+ + + + F LVI VD D G+Y C A NS G + A + Sbjct: 7977 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHS-DVGEYSCKADNSVGAVASSAVLV 8035 Query: 923 IDVEKVT--FVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978 I K+ F + L+ +ET G V EC+ S + WY + + + + Sbjct: 8036 IKERKLPPFFARKLKDVHET-LGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFV 8094 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE-TIPEF--IRKLQ-DFEVKE 1030 +G C + +S L++ E +P F ++ + D + E Sbjct: 8095 HNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGE 8154 Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC- 1089 V + + W +D I+P N Y + L + D G+Y+C Sbjct: 8155 SGTFKCHV-TGTAPIKITWAKDNREIRPGGN-YKMTLVENTATLTVLKVGKGDAGQYTCY 8212 Query: 1090 ---ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT-FEIELTKGDAL-VRWFKDGS 1144 I +SC+A + V E PP I +L+ ++ K ++ T +E ++ + V W+KD + Sbjct: 8213 ASNIAGKDSCSAHLGVQE-PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 8271 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTL 1200 EIQ S+ +++ L++++ ++D+G+Y+CE G++ + L V+EP I Sbjct: 8272 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPI--FR 8329 Query: 1201 RLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 + P I D +L E+ V+WYK K + +K+ ++S+ ++ I Sbjct: 8330 KKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVD 8389 Query: 1260 EDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 D EY C D S T + ++ PP+ V + G +V L + + Sbjct: 8390 AADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPIS 8449 Query: 1319 DEWIVN-SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W + +I+++ + S A+L +VE +AG Y +++N+ G + +++ Sbjct: 8450 VVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV 8509 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT 1436 L+ + KP +++ + + C E G + + + +E+ + + K Sbjct: 8510 LEPATIVEKPESIKVTTG--DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 8567 Query: 1437 Q-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 I N+ + S + N V + + + + P+ + LK Sbjct: 8568 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV-----SDRTVPPSFTRKLKETNGLS 8622 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCI 1551 + + C G P V+W+ +G ++ + + +N Y CI Sbjct: 8623 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 8682 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 A N G E S + +++ P + D G T++++G PP V W+K + Sbjct: 8683 ATNMAGSDECSAPLTVREPPSF-VQKPD-PMDVLTGTNVTFTSIVKGTPPFSVSWFKGSS 8740 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +L N++ ++ + + + ++ S S +YT SN AG +S L + Sbjct: 8741 ELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 8791 Score = 256 bits (627), Expect = 5e-66 Identities = 198/757 (26%), Positives = 326/757 (43%), Gaps = 35/757 (4%) Query: 1218 VEIPDETLDVTWYK--KKSVIEDTEKFTLISDVK---KRTLIIRKCTEDDQCEYTCVLLD 1272 +E+ ++ D WY+ + I +TE FT + D+K K + + EY+ + + Sbjct: 30305 LEMQEKDTD-QWYRVHTNATIRNTE-FT-VPDLKMGQKYSFRVAAVNVKGMSEYSESIAE 30361 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + ++++ +E D ++ I+ G+ + L+V P P W + + I Sbjct: 30362 IEPVERIEIPDLELAD---DLKKTVTIRAGASLRLMVSVSGRPPPVITW--SKQGIDLAS 30416 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 + L + KV DAG Y + EN G + V + D P P + E+ Sbjct: 30417 RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEV 30476 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRF 1451 S+ I W+ P G + + Y+VE +E + +V +KT I L + Y F Sbjct: 30477 SRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYF 30536 Query: 1452 RAYAVNEVDISDASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 R N I + ET++ V + K++ V K + E + + G Sbjct: 30537 RVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGY 30596 Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCV 1564 V + K+ T K T ++ A N+ G E T Sbjct: 30597 VLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYL---FRIRAQNEKGVSEPRETVTA 30653 Query: 1565 VGIQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 V +Q P I +S K H G + I G PPP W+ G+KL + Sbjct: 30654 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 30713 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 + T K + + I+E + +YT+E N GT+S + + + DKP P GP+ + EI Sbjct: 30714 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 30773 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMF 1739 S+TI W+PP DGG L+ Y +E+ + W+ V++ V R T+ +L E EY+F Sbjct: 30774 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTR--STFKFTRLTEGNEYVF 30831 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 RV A N G L+SE I ++++ +P + + + +TW+P E +GGS + Sbjct: 30832 RVAATNRFGIGSYLQSEVIECRSSIRIPG-PPETLQIFDVSRDGMTLTWYPPEDDGGSQV 30890 Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDK 1856 Y VE K+ +W R + L+ Y+ R+ A N G+ P Sbjct: 30891 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30950 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 I + PP +P+N V+++T SV+L W+ PE GGS +T Y+IE + V WTK Sbjct: 30951 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCN 31010 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 T + E+ + ++ + E FR+ A N G P E Sbjct: 31011 TTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAE 31047 Score = 252 bits (616), Expect = 1e-64 Identities = 252/1068 (23%), Positives = 432/1068 (40%), Gaps = 60/1068 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +K V G LEC++ PE + W G+ + + + + + Sbjct: 6630 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI---- 6685 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S L+I +V++ GTYT N G++S V+ + + PP LK+ G S Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDV-SDRAVPPSFTRRLKNTGGVLGASC 6744 Query: 753 ILSAQVVGNPRPTITWC-KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810 IL +V G+ ++ W + K V ++ + T+ L D G YT A N Sbjct: 6745 ILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 6804 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G E AV+TV+EP P F+ + + V + + + P + W+R Sbjct: 6805 AGSDECRAVLTVQEP-------PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 6857 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + + F+ EL + N+D SG+Y CV SN+AG++S R+ + E F Sbjct: 6858 RELVKGDRCNIYFEDTVAELELFNIDIS-QSGEYTCVVSNNAGQASCTTRLFVK-EPAAF 6915 Query: 931 VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 +K L + E GK++ILE + T +S W + I+ + I+ + Sbjct: 6916 LKRLS-DHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILN 6974 Query: 989 XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSET 1044 D G C ++++ + LV P F+ +L+ E D L+ ++ + Sbjct: 6975 STKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPE 7034 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV- 1103 V W + ++P +Y ++ L +++D GEY+C + TA V Sbjct: 7035 ITVSWYKGDTKLRPTP-EYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVF 7093 Query: 1104 -----ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID 1157 +LPP +L++ + G T L + V W++DG ++ ++Q + Sbjct: 7094 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFV 7153 Query: 1158 GKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN--FTLRLPEFILVPAN 1211 LKI DL +G+YSC +G + +A LT EP + F ++ P I V A Sbjct: 7154 DNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIK-PVSIDVIAG 7212 Query: 1212 TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 A + + + +TW K I +T+ L I K + D +YTC Sbjct: 7213 ESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 7272 Query: 1271 LD--AKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVN-SK 1326 + K ++ V E PPK V ++ K+G + L P+ W N S+ Sbjct: 7273 TNDVGKDMCSAQLSVKE-PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSE 7331 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + + K+ I+S A LTI + D+G Y N G A +T+ P K Sbjct: 7332 LHESWKYNMSFINSV-ALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQK 7390 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 P+ + S I E T +++ Q ++ ++ T I NL+ + Sbjct: 7391 PSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEAS 7450 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 + A NEV SD + +K + P K L + +T + +EL I Sbjct: 7451 DVGEYHCKATNEVG-SDTCSCSVKFK-------EPPRFVKKLSDTSTLIGDAVELRAIVE 7502 Query: 1507 GVPQPKVTWYRD-GKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G V W +D G+ ++ ++ T +N Y C ND G E Sbjct: 7503 GFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMREC 7562 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 S V+ + + I E + G+ + + V+ G P W+K+G +L D +++I Sbjct: 7563 SAVLTVLEPARIIEKPEPMTV--TTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHI 7620 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 T K + ++I + S Y+ E N+ G S+ V++ V D+ P Sbjct: 7621 TFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPP 7668 Score = 251 bits (615), Expect = 1e-64 Identities = 271/1159 (23%), Positives = 474/1159 (40%), Gaps = 79/1159 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + E PPTF +PK+ G C + P + W G + P N ++ + Sbjct: 4472 VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAEN 4531 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 H +L+++N+ G Y+ A N+ G A + I + + +EP++S I Sbjct: 4532 KH----ILELSNLTIQDRGVYSCKASNKFG-ADICQAELIIIDKPHFIKELEPVQSAI-- 4584 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKP-KKVKDEGVYTL 805 + V L QV + + T+TW K+ + + K + T+ P K+KD G Y Sbjct: 4585 -NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVC 4643 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSI 864 A N G + SA +TV EPP F+ + + G + +L ++ +PV + Sbjct: 4644 TASNEAGSSSCSATVTVR-------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV 4696 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TW++NN+ +S S T+ F L IT+V E DSG Y C A N G S + I Sbjct: 4697 TWFKNNKELSESNTVRMYFVNSEAILDITDVKVE-DSGSYSCEAVNDVGSDSCSTEIVIK 4755 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXX 982 E +F+K L+ + + G +L+C+ S T W+ +KK+I + + Sbjct: 4756 -EPPSFIKTLEPA-DIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLV 4813 Query: 983 XXXXXXXXXXDVGVIKCIVKDQ--ETSTML--VVKETIPEFIRKLQDFEVKEKDVAILEV 1038 DVG +C+V ++ + M ++KE P F++K+ D L+ Sbjct: 4814 CLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEP-PTFVKKVDDLIALGGQTVTLQA 4872 Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095 + SE V W + E+I+ + K + L I + + G+Y+C+ +E+ Sbjct: 4873 AVRGSEPISVTWMKGQEVIR-EDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS 4931 Query: 1096 -CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153 + +V+ P +II R + +V G+ AT E + L +W+KDG + S + Sbjct: 4932 QTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4991 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSIN--FTLRLPEFIL 1207 ++ +LK Y +L D+G+Y S EVG+S C TV + I FT L Sbjct: 4992 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDS 5051 Query: 1208 VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 V N L +I + V+W+K I ++++ + +L I + +D + Sbjct: 5052 V-VNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNF 5110 Query: 1267 TCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 TC ++ S +V+ PP V + GS V L +Q W + Sbjct: 5111 TCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 5170 Query: 1326 KII---KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 K + C TK +++S SL + V+ +D+G Y ++ N G + N+ + + + Sbjct: 5171 KELVSGGSCYITKEALES---SLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT 5227 Query: 1383 PPGK---PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT 1438 K +L+ ++ C + TG I I + +EI + + + T Sbjct: 5228 FVEKLEPSQLLKKGDATQLAC----KVTGTPPIKITWFANDREIKESSKHRMSFVESTAV 5283 Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 + ++ S + A NE S ++KE SP K K I Sbjct: 5284 LRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV----IVKE----SPYFTKEFKPIEVLKEY 5335 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXXXXXXXXXXXXXXXYKCIAF 1553 D+ L G P ++TW++D L++ + T+ ++ Y+C Sbjct: 5336 DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVT 5395 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N+ G S V +++ P E G A ++G P V W K+ +++ Sbjct: 5396 NEVGSSICSARVTLREPPSFIKKIESTSSLR--GGTAAFQATLKGSLPITVTWLKDSDEI 5453 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 D +T + + + + ++ H KY +A N AG L V + + E V Sbjct: 5454 TEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAV 5513 Query: 1674 IMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWIKVADVDR-DVETYCIQKL 1731 + + T++ K G E+T K+ + E K++ D + + Sbjct: 5514 SIDVTQGDPATLQVK---FSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEK 5570 Query: 1732 NENCEYMFRVIAQNPVGFS 1750 ++ EY F V QN VG S Sbjct: 5571 KDSGEYTFEV--QNDVGRS 5587 Score = 248 bits (608), Expect = 1e-63 Identities = 245/1035 (23%), Positives = 430/1035 (41%), Gaps = 63/1035 (6%) Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723 ++ W F+ + + DE D + Y V+ N + Q G Y A+N G+ + Sbjct: 4317 EVNWYFENKLVPSDEKFKCL--QDQNTYTLVIDKVNTEDHQ-GEYVCEALNDSGKTATSA 4373 Query: 724 VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPT 780 K+ ++ P + ++ + V G + ++ P W K + + Sbjct: 4374 --KLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSI 4431 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ 840 +S S+ IL+ + V D G YT KA N G +A +TV E A PP F++R + Sbjct: 4432 RSSKYISSLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTE-----AYPPTFLSRPK 4485 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV-ITNVDSEI 899 +T K + VT PV W ++ +SPS + D EN ++ ++N+ + Sbjct: 4486 SLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKIS-DAENKHILELSNLTIQ- 4543 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957 D G Y C ASN G A + I ++K F+K L+ ++ K V LECQ V+ Sbjct: 4544 DRGVYSCKASNKFGADICQAELII-IDKPHFIKELEP-VQSAINKKVHLECQVDEDRKVT 4601 Query: 958 TKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016 W + +++ G D++ I E + D G C ++ S+ T+ Sbjct: 4602 VTWSKDGQKLPPGKDYK-ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 4660 Query: 1017 ---PEFIRKLQ-DFEVKEKDVAILEVEIN-SETADVVWERDG-EIIKPKKNKYDFEKRGH 1070 P F++K+ + + + A L ++ S V W ++ E+ + + F Sbjct: 4661 REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 4720 Query: 1071 IRKLYIRNTSVHDEGEYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATF 1126 I L I + V D G YSC + D +SC+ E+ + E PP I L+ + +G A Sbjct: 4721 I--LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE-PPSFIKTLEPADIVRGTNALL 4777 Query: 1127 EIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181 + E++ G + WFKD +I+ S +L L+I+ + D GEY C EVG Sbjct: 4778 QCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 4837 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 C A ++EP F ++ + I + T E + VTW K + VI + K Sbjct: 4838 KCGCMATHLLKEPP-TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGK 4896 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300 + LII +YTC+ +A S T + +V+ P KI++ ++ Sbjct: 4897 IKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVT 4956 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 G TL P+ +W + + + K + S + A L E D+G Y Sbjct: 4957 AGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTF 5016 Query: 1361 RLENNCGHADVEMNVTILDKPSPP--GKPNILEIDSSSINICWDEPENTGNSTI-IYYVV 1417 + N G + E T+LD+ P KP + +DS C + + G+ + + + Sbjct: 5017 EISNEVGSSSCETTFTVLDRDIAPFFTKP-LRNVDSVVNGTCRLDCKIAGSLPMRVSWFK 5075 Query: 1418 EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + +EI ++ + + T + I + N + F A N V D+S +++E Sbjct: 5076 DGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL----IVQE 5131 Query: 1477 TKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535 V KP K++ P + L F G + W++ K+L + + Y + Sbjct: 5132 PP---SFVTKPGSKDVL--PGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEAL 5186 Query: 1536 XXXXXX----XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C N G VE S + +++ P + + Q K GD Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE-PATFVEKLEPSQLLKKGDATQ 5245 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + + G PP ++ W+ N +++ ++ ++ E T+V+R+ ++ S +Y EA N A Sbjct: 5246 LACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEA 5305 Query: 1652 GTSSVEVTLKVYDKP 1666 G+ + V + P Sbjct: 5306 GSDHCSSIVIVKESP 5320 Score = 248 bits (606), Expect = 2e-63 Identities = 190/706 (26%), Positives = 301/706 (42%), Gaps = 43/706 (6%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK---HTKPS-----IDSKSASLTIKKVE 1351 K GS + + + P P W + K K K H P S+ + I + + Sbjct: 16750 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 16809 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 + G Y + +N G V ++D P PP + +I S + W P++ G Sbjct: 16810 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDR 16869 Query: 1412 IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE- 1469 I YV+E + ID W V + T + +L + Y FR A N I ET + Sbjct: 16870 IKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQR 16929 Query: 1470 ------YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 Y K++ + K +++ +P ++ + + + + + W G K + Sbjct: 16930 TTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC-LAWDPTGTKKE 16988 Query: 1524 TAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNE 1578 + + ++ A N G + S VG Q+P + S Sbjct: 16989 AWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI- 17047 Query: 1579 DIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE-------YNITTKEKTSV 1629 D+K+ +V G + A I+G+P P + W+K K ++KE N + T Sbjct: 17048 DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCT 17107 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689 + I + +RS + YTI A N GT+S E+ L V +P P GP+ +S + +T+ W P Sbjct: 17108 LVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFP 17167 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 P DDGG ++T Y IEK E + W+ V+ ++ TY I KL E EY+FR++AQN G Sbjct: 17168 PKDDGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHEYVFRIMAQNKYGI 17226 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ- 1808 E L+SEP + VP + S+ + W E +GGSP+ Y +E+K Sbjct: 17227 GEPLDSEPETARNLFSVPG-APDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDT 17285 Query: 1809 EGKKWK------XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 K+WK ++ L + YQFR+YA N G D T Sbjct: 17286 TSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 17345 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 + PP P V++ T S L+W+ P +GGS +T YI+E+K + W K Sbjct: 17346 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 17404 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 + + +KE FR+SA N G+ P E V +E + SP Sbjct: 17405 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDV-IEMKDRLVSP 17449 Score = 247 bits (605), Expect = 2e-63 Identities = 188/685 (27%), Positives = 304/685 (44%), Gaps = 31/685 (4%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 K G DV +L+ ++ P P W + K + +++ + DS S LTI +V D G Y Sbjct: 28211 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL-LTIPQVTRNDTGKY 28269 Query: 1359 KLRLENNCGHADVE-MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 L +EN G ++V +LD P+ K + + ++ + WD P G S II YV+ Sbjct: 28270 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 28329 Query: 1418 EYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 E ++ W V + + T + +L + + FR A NE+ I + ETTE +K Sbjct: 28330 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE---PVKA 28386 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPKVTWYRDGKKLKT-AKATYENRX 1533 ++ +P + +K+ +T+ + + T GG + R GK +T + A Sbjct: 28387 AEVPAPIRDLSMKD-STKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTC 28445 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ------KHKVG 1587 ++ A N+ G + + I K +I D+ ++G Sbjct: 28446 EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVRIG 28505 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + +G P P + W K+G L+ + + E + IK K+ H KYT+ Sbjct: 28506 HNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVIL 28565 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 N +V +T+ PSKP+GP+ EI +SV + W P D+GG E+T Y+IEK E Sbjct: 28566 DNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRE 28625 Query: 1708 PDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 W V + V R T+ + L ++ EY FRV A+N G S+ L S IV K + Sbjct: 28626 TSQTNWKMVCSSVAR--TTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRI 28683 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXX--XXXX 1823 P + ++ + +TW +GGS + + VE K+ W+ Sbjct: 28684 PG-PPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGRE 28742 Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVSESTSRSV 1882 R L YQFR+YA N G S P + K T+ + PP P +++ + T ++ Sbjct: 28743 YRATGLVEGLDYQFRVYAENSAGLSSP-SDPSKFTLAVSPVDPPGTP-DYI--DVTRETI 28798 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 TLKW P +GGS I Y IE K + W + S ++ + + D FRI A Sbjct: 28799 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 28857 Query: 1943 ENTVG-VSLPTESQSVRLEKHATVP 1966 N VG +S P++S + + + VP Sbjct: 28858 RNAVGTISPPSQSSGIIMTRDENVP 28882 Score = 245 bits (600), Expect = 9e-63 Identities = 188/708 (26%), Positives = 303/708 (42%), Gaps = 35/708 (4%) Query: 1287 PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 PP+I D + ++ + + L V + P+P +W I+ + + S Sbjct: 26031 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTD--RAQIEVTSSFT 26088 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L I V D+G Y L LENN G +NV +LD PS P I E+ S+ + W+ Sbjct: 26089 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 26148 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 P G + I Y+VE +E + ++ N TKT I+NL+ SY FR A NE I Sbjct: 26149 PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 26208 Query: 1463 DASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 +ETTE KV + ++ V + I E E + I G V + + + Sbjct: 26209 LPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT---KG 26265 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC----VVG--IQQKPV 1572 +K T T ++ A N+ G + V+ I+ KP Sbjct: 26266 SEKWSTC--TQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPS 26323 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 + + K + ++ + +G P V W K+G L+ N+++ + + + I Sbjct: 26324 VELPFHTFNVKAR--EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 26381 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 KE + Y + SN+AG+ +V +T+ V D+P P GP+ + E+S +S+TI W PP Sbjct: 26382 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEY 26440 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 DGG +++ Y +EK E + W V+ + I +L EY FRV A+N G S Sbjct: 26441 DGGCQISNYIVEKKETTSTTWHIVSQAVART-SIKIVRLTTGSEYQFRVCAENRYGKSSY 26499 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK- 1811 ES +V + P ++ +TW +GGS +I Y +E K+ Sbjct: 26500 SESSAVVAEYPFSPPGPPGTPKVVHA-TKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSI 26558 Query: 1812 KWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W ++ L Y++R+YA N G S + + PP QP Sbjct: 26559 LWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQP 26618 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929 V+ T +SV+LKW++P +GG+ IT YI+E + + W K + Sbjct: 26619 E---VTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTE 26675 Query: 1930 IKEKDEIIFRISAENTV-GVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 + E FR+ A N VS P+ES + K PP ++++ Sbjct: 26676 LTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDV--EPPRVMMDVK 26721 Score = 245 bits (599), Expect = 1e-62 Identities = 274/1209 (22%), Positives = 485/1209 (40%), Gaps = 96/1209 (7%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 VEK + + + EC V G P ++ W + I PS+ F M +++ NVA+ I+ Sbjct: 6071 VEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN-NVASFRIQS 6129 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 V +D+G +T +N F SS+ + + + + I Sbjct: 6130 VMKQDSGQYTFKVEN--DFGSSSCDAYLRV-------------------------LDQNI 6162 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F+KK GS I +EC++ W G+EI + S H Sbjct: 6163 PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEI----STSAKYRLVCHERS 6218 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGES 751 L++ N++ YT N G+ + +L +K EPP +++P + + + Sbjct: 6219 VSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK----EPPSFLVKPGRQQAIPDS-T 6273 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809 V A + G P I W K++ + + P G S + L V G YT N Sbjct: 6274 VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR 868 G + ++ V EPP F+ + + + + G + +L ++ +P + W+R Sbjct: 6334 DVGSDSCTTMLLV-------TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFR 6386 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N + S+ F + + N+ +E DSGD+ C A N AG +S +V + V Sbjct: 6387 NEHELPASDKYRMTFIDSVAVIQMNNLSTE-DSGDFICEAQNPAGSTSCSTKVIVKEPPV 6445 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 ET + V LEC+ S T WY +K+++ +I + Sbjct: 6446 --FSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 6503 Query: 987 XXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042 D+G C +++ +T V + P F+ KL V + A L+ I + Sbjct: 6504 LNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGA 6563 Query: 1043 ETADVVWERDGE-IIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE- 1099 + V W ++ E +I+ +N + F + ++ L + G+Y C ++++ E Sbjct: 6564 QPIFVQWLKEKEEVIRESENIRITFVE--NVATLQFAKAEPANAGKYICQIKNDGGMEEN 6621 Query: 1100 -VTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 T++ L P +I V G T E ++ L V W+KDG + S + + Sbjct: 6622 MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF 6681 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFILVPA 1210 K L+I + DAG Y+ +V G S CTA++ V + ++ +FT RL V Sbjct: 6682 YNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGV-L 6740 Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 L ++ + + V W+ +K+ I K+ TL + D YTCV Sbjct: 6741 GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 6800 Query: 1270 LLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 + + + + V V+ PP V + G +VT + P W ++ + Sbjct: 6801 AANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAREL 6860 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 K + A L + ++ + +G Y + NN G A + + + + + + Sbjct: 6861 VKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLS 6920 Query: 1389 ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 ++ I E TG I + + + I T+E ++ +T +T I + NS Sbjct: 6921 DHSVEPGKSIIL--ESTYTGTLPISVTWKKDGFNITTSEKCNI--VTTEKTCILEI-LNS 6975 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + R E++ ++A + + T ++ P L+ + + + L C G Sbjct: 6976 TKRDAGQYSCEIE-NEAGR--DVCGALVST-LEPPYFVTELEPLEAAVGDSVSLQCQVAG 7031 Query: 1508 VPQPKVTWYRDGKKLKTAKA--TY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 P+ V+WY+ KL+ TY N Y C A N G + Sbjct: 7032 TPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKT 7091 Query: 1564 VVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 V IQ++ P +DI+Q VG +T + G P +V WY++G L +D+ Sbjct: 7092 VFRIQERQLPPSFARQLKDIEQT--VGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQ 7149 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP---EGPVIMRE 1677 + + + ++I + SHS +Y+ ASN GT+S L + P PV + Sbjct: 7150 TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDV 7209 Query: 1678 ISRESVTIE 1686 I+ ES E Sbjct: 7210 IAGESADFE 7218 Score = 244 bits (598), Expect = 2e-62 Identities = 242/1086 (22%), Positives = 448/1086 (41%), Gaps = 65/1086 (5%) Query: 633 PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F KK + ++ V + EC++ PE + W EI ++ + Sbjct: 8231 PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSV--- 8287 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +VL++ N+ G YT A N G AS LK+K EPP + + +G Sbjct: 8288 -AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK----EPPIFRKKPHPIETLKGAD 8342 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V L ++ G P ++W K+ + + K S+ SI IL D G Y KA Sbjct: 8343 VHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA-DIGEYQCKAT 8401 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G I ++ P P F+ + +I+ ++L + S+ W++ Sbjct: 8402 NDVGSDTCVGSIALKAP-------PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK 8454 Query: 869 NN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 + EI+ S+ I ++ ENI + + ++G Y C N AG A +++ +E Sbjct: 8455 DKGEIVRESDNIWISYS-ENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV-LEP 8512 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 T V+ +S + G T LEC + T +STKW+ + KE++ + +I + Sbjct: 8513 ATIVEK-PESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLK 8571 Query: 986 XXXXXXXDVGVIKCIV-----KDQETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVE 1039 D GV V KD T+++ V T+P F RKL++ ++E + Sbjct: 8572 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECK 8631 Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094 + S V W +G I + KY + L + D G+Y+CI + + Sbjct: 8632 VYGSPPISVSWFHEGNEISSGR-KYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSD 8690 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHI 1152 C+A +TV E PP + + V G TF + KG V WFK SE+ + Sbjct: 8691 ECSAPLTVRE-PPSFVQKPDPMDVLTGTNVTFT-SIVKGTPPFSVSWFKGSSELVPGDRC 8748 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 ++++ +L+++D D +GEY+C E G + CT L ++ P+ F RL ++ + Sbjct: 8749 NVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA-KFVKRLNDYSIE 8807 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 + VTW K + +++ + + K L I T +D +Y C Sbjct: 8808 KGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNC 8867 Query: 1269 VLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + +A K + ++ ++E PP V ++ G +L P+ W Sbjct: 8868 YIENASGKDSCSAQILILE-PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDT 8926 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 ++ K + A+L +V+ D+G Y + EN+ G +T+ ++ PP Sbjct: 8927 KLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSF 8986 Query: 1387 PNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444 L ++ + +D + + + + + + + + + T T + K Sbjct: 8987 SRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTAT-LNIFK 9045 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 T+ S + I AS + ++ E K P + L + E + C Sbjct: 9046 TDRSLAGQYSCTATNPIGSASSSARL--ILTEGK-NPPFFDIRLAPVDAVVGESADFECH 9102 Query: 1505 FGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G KV+W +D +++++ + +Y EN Y C A N+ G+ Sbjct: 9103 VTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDS 9162 Query: 1561 TSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + + I+++ + + + + + G+ + + + G P V WYKN +++ Sbjct: 9163 CTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSN 9222 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 IT K T V+++++ + + YT + SN AG++ ++ V +P KP PV + + Sbjct: 9223 CEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI-VIKEPKKP--PVFDQHL 9279 Query: 1679 SRESVT 1684 + +V+ Sbjct: 9280 TPVTVS 9285 Score = 244 bits (596), Expect = 3e-62 Identities = 272/1208 (22%), Positives = 492/1208 (40%), Gaps = 98/1208 (8%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 +EK P G+ EC V G P WF+ + + + + VA+L I Sbjct: 7575 IEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFIN-KVASLKIPC 7633 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 D G ++ KN+ G ++ T +S H S+ V Sbjct: 7634 AEMSDKGLYSFEVKNSVGKSNCT--------VSVHVSDRIV------------------- 7666 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F +K K G+ ++LECR+ + W G EIV + ++ C Sbjct: 7667 PPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENV---C 7723 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L ++ ++ G YT VA N G VL + +EPP + S+ V G S+ Sbjct: 7724 T-LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTV----QEPPSFEQTPDSVEVLPGMSL 7778 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810 ++ + G P + W K ++ + + + +T L+ +V+ + G Y+ N Sbjct: 7779 TFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTND 7838 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A + + V+EP F+ R + +V+ I L A T P S++W ++ Sbjct: 7839 AGSASCTTHLFVKEPA-------TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDE 7891 Query: 871 EIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 +IS SE +IT +E++ + ++ D Y C+ N AG+ A V++ +E Sbjct: 7892 YLISQSERCSITMTEKSTILEILESTIE---DYAQYSCLIENEAGQDICEALVSV-LEPP 7947 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 F++ L+ E G+ L+C+ T + WY ++ ++ + Sbjct: 7948 YFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 8006 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040 DVG C + +S +LV+KE P F RKL+D E I Sbjct: 8007 NKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECRI 8066 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 N SE V W +DG ++K N ++ L I T G+Y+C + TA Sbjct: 8067 NGSEPLQVSWYKDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTAS 8125 Query: 1100 ------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151 ++ E+PP + + + G TF+ +T G A ++ W KD EI+ + Sbjct: 8126 SSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVT-GTAPIKITWAKDNREIRPGGN 8184 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRL-PEFI 1206 ++T+ L + DAG+Y+C G C+A L V+EP F +L P I Sbjct: 8185 YKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPP-RFIKKLEPSRI 8243 Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + Y + V WYK ++ I+++ KF + L + + +D +Y Sbjct: 8244 VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDY 8303 Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 TC +A + + V+ PP +G+DV L + Q P + W + Sbjct: 8304 TCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDK 8363 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 + ++ K K ++ S+ I V+ D G Y+ + N+ G ++ + P Sbjct: 8364 RELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVK 8423 Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISV-KNITKTQTSIQ 1441 K +I + + + E +++++ + + + ++ WIS +NI Q S Sbjct: 8424 KLSDISTVVGKEVQL-QTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFS-- 8480 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 ++ ++ ++ N+ + + T V++ I VEKP ++I + L Sbjct: 8481 RVEPANAGKYTCQIKNDAGMQECFAT---LSVLEPATI----VEKP-ESIKVTTGDTCTL 8532 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHG 1557 C G P+ W++DGK+L + K ++ N+ Y N G Sbjct: 8533 ECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 + + + + + V +K+ + + G ++ + G PP V W+ GN++ + Sbjct: 8593 KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSG 8652 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 ++Y T + T + + L+ S S YT A+N AG+ L V + PS + P M Sbjct: 8653 RKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMD 8712 Query: 1677 EISRESVT 1684 ++ +VT Sbjct: 8713 VLTGTNVT 8720 Score = 243 bits (595), Expect = 4e-62 Identities = 244/1062 (22%), Positives = 433/1062 (40%), Gaps = 60/1062 (5%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L+C++ ++W G+EI + +A + L+I V G +T A Sbjct: 5059 LDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT----ASLEIIRVDMNDAGNFTCRA 5114 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N G L ++ EPP + S V G +V L + G+ TI W K N Sbjct: 5115 TNSVGSKDSSGALIVQ----EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 5170 Query: 773 KPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 K + + + + S L K D G YT K N G E SA + V+EP Sbjct: 5171 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPAT--- 5227 Query: 831 EPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 F+ + + + +KG +L +VT P ITW+ N+ I S +F Sbjct: 5228 ----FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAV 5283 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL- 948 L +T+V E DSG+Y C A N AG S H + + I E F K + +E ++L Sbjct: 5284 LRLTDVGIE-DSGEYMCEAQNEAG-SDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLA 5341 Query: 949 ECQTSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007 E + W+ + + SG ++ IQ+ D G +C V ++ S Sbjct: 5342 EVAGTPPFEITWFKDNTILRSGRKYKTFIQD-HLVSLQILKFVAADAGEYQCRVTNEVGS 5400 Query: 1008 TMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKN-K 1062 ++ + T+ P FI+K++ A + + S V W +D + I N + Sbjct: 5401 SICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIR 5460 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKV 1118 FE ++ LY+ V +G+Y C ++++ C+A ++V E P I + V Sbjct: 5461 MTFEN--NVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE-PATITEEAVSIDV 5517 Query: 1119 NKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 +G+ AT +++ + + +WFKDG E+ + ++++ LKI + D+GEY+ Sbjct: 5518 TQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 5577 Query: 1178 CEV----GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 EV G S C A + V + I +FT +L + + + + + + W+K Sbjct: 5578 FEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFK 5637 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI 1290 I +EK+ L I + D YTC + + + V+ PP Sbjct: 5638 DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYF 5697 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 V+ + + + V L +W ++K + D S SL + Sbjct: 5698 VEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAA 5757 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 + TD+G Y +L N+ G A + + + + P KP+ + + + + + E + TG Sbjct: 5758 KATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTF-ECQITGTP 5816 Query: 1411 TI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 I + + ++ EI + + I T I + +S + A N+ + S Sbjct: 5817 KIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 5876 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA- 1527 + +KE PT + LK + D+EL C G P +VTW ++ ++++++K Sbjct: 5877 K----VKEP----PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKY 5928 Query: 1528 TYENRXXXXXXXXXX---XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584 T +R Y+CI N+ G S V +++ P E+ Sbjct: 5929 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVL 5988 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K + T + G PP + W K+ L+ D I+ + + ++I+ + HS +YT Sbjct: 5989 KSSATFQST--VAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYT 6046 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 +A N +G L V + E + ++ +T+E Sbjct: 6047 CQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLE 6088 Score = 243 bits (594), Expect = 5e-62 Identities = 176/609 (28%), Positives = 276/609 (45%), Gaps = 30/609 (4%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436 DKPS PG+ IL I S+ + W++PE G I+ Y VEY++ + W + + I Sbjct: 31356 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 31415 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 Q +I L + Y FR +A NE +S T K K T ++P + K +K++TT+ Sbjct: 31416 QFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKT-KLTSGEAPGIRKEMKDVTTKLG 31474 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIA 1552 E +L+C G P P + WYR GK+L + K + + R Y CIA Sbjct: 31475 EAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIA 31534 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNG 1610 N+ GEVETS + +Q P +K+K+ VG + + G P P + W+ Sbjct: 31535 TNEVGEVETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQ 31593 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 L+N + I E + + +K ++R +H+ KY ++ SN GT + +++ DKP KP Sbjct: 31594 KLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKP 31653 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 GP+++ + + S I WKPP DDGG +T Y +EK E ++ V T I Sbjct: 31654 TGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIV 31713 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 L EN Y FRV AQN G S+ LE S ++IK+ + P + +S + W Sbjct: 31714 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPG-APGKPTITAVTKDSCVVAW 31772 Query: 1789 FPSEKNGGSPIIDYKVEIKQEGK--KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNE 1844 P +GG+ I +Y +E K+E K KW ++ L Y+FR+ N Sbjct: 31773 KPPASDGGAKIRNYYLE-KREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENL 31831 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQP------RNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 G S + IT K+ P P RN V ++ ++ K T PI Sbjct: 31832 GGESEWSEISEPIT-PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVT----GHPKPIV 31886 Query: 1899 NYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + + K + +I G H+ I ++ + D ++++ A N G T S V Sbjct: 31887 KWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 31946 Query: 1958 RLEKHATVP 1966 + +P Sbjct: 31947 EVPAKIHLP 31955 Score = 242 bits (593), Expect = 6e-62 Identities = 215/796 (27%), Positives = 348/796 (43%), Gaps = 54/796 (6%) Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 +I +L+LP F L +EIP +++W K ++ T + + Sbjct: 25236 TIQPSLKLP-FNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 25294 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 L I++ +DD +YT ++ T L V V+E P V R S +++ Sbjct: 25295 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG---PVRFDEVSADFVVI 25351 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL---TIKKVENTDAGIYKLRL--EN 1364 ++ P +++ I++K T + SA++ TIK + Y+ R+ EN Sbjct: 25352 SWEP-PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAEN 25410 Query: 1365 NCGH-ADVEMNVTILD----KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 G A ++ I+ +P PPG P + I + + W EP N G + II Y +E Sbjct: 25411 RYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 25470 Query: 1420 QEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E ++ W+ + I T+ L Y F+ A N V I S+ +E + + Sbjct: 25471 KEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF--VARD 25528 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPKVTWYRDGKKL----KTAKATYEN 1531 P +P + T N ++ GG K+T Y KK + KA++ N Sbjct: 25529 PCDPPG--RPEAIVITRNNVTLKWKKPAYDGG---SKITGYIVEKKDLPDGRWMKASFTN 25583 Query: 1532 RXXXXXXXXXXXXXXXY--KCIAFNDHGEV-ETSCVVG-IQQKPVITISNEDIKQKHK-- 1585 Y + IA N G E S G I + I N + K+K Sbjct: 25584 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 25643 Query: 1586 ----VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNI-TTKEKTSVIRIKELKRSH 1639 G+ +++ A I G P P+V+W K+G +LE I +T +KT+++ +K+ R+ Sbjct: 25644 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV-VKDCIRTD 25702 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 +Y ++ SN GT S+ +T+KV D+P PEGP+ + ++ E + W PPL DGG ++ Sbjct: 25703 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 25762 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y IEK E W +V+ + Y + KL EY+FRV+A N G E LES P+ Sbjct: 25763 HYIIEKRETSRLSWTQVS-TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 25821 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XX 1816 P I +S+ +TW +GG+ I Y +E + +EG +W Sbjct: 25822 ACNPYK-PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 25880 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 R+ L+ +Y+FR+ A N G P L PP P N V++ Sbjct: 25881 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTD 25940 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDE 1935 ++ SV+L W++P +GG+P+ Y++E K WT G + + +KE E Sbjct: 25941 TSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 26000 Query: 1936 IIFRISAENTVGVSLP 1951 FRI A N+ GV P Sbjct: 26001 YNFRICAINSEGVGEP 26016 Score = 240 bits (588), Expect = 3e-61 Identities = 245/1068 (22%), Positives = 429/1068 (40%), Gaps = 65/1068 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F +KP++Q V+ + + L+ + I W +E+ SV + Sbjct: 5694 PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTS---- 5749 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751 + L++ K GTY N G A+ L +K EPPQ I+ P +++R G+S Sbjct: 5750 TSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK----EPPQFIKKPSPVLVLRNGQS 5805 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI--LKPKKVKDEGVYTLKAEN 809 Q+ G P+ ++W + + A+ + + +V++ G Y +A N Sbjct: 5806 TTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARN 5865 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G A S + V+EP P FI + + V + ++L VT P +TW +N Sbjct: 5866 DAGTASCSIELKVKEP-------PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKN 5918 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 N I S+ T L IT D D+G+Y+C+ SN G S RV + E + Sbjct: 5919 NREIRSSKKYTLTDRVSVFNLHITKCDPS-DTGEYQCIVSNEGGSCSCSTRVALK-EPPS 5976 Query: 930 FVKHLQKSYET-EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 F+K ++ + + T S +S W + + + D+ I Sbjct: 5977 FIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRS 6036 Query: 989 XXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSE 1043 G C K++ L+V+E + + K + +V EKD LE V + Sbjct: 6037 VDNGHSGRYTCQAKNESGVERCYAFLLVQEPA-QIVEKAKSVDVTEKDPMTLECVVAGTP 6095 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAE 1099 V W +DG+ I P + + ++ I++ D G+Y+ + ++ SC A Sbjct: 6096 ELKVKWLKDGKQIVPSRY-FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAY 6154 Query: 1100 VTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 + V++ +PP +L G+ E +++ + +WFKDG EI S +L Sbjct: 6155 LRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC 6214 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 + L++ + +L+D Y+C+V G+ C+ ILTV+EP +F ++ +P +T Sbjct: 6215 HERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP-SFLVKPGRQQAIPDST 6273 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLL 1271 + + + W+K + K + + L + +YTC V Sbjct: 6274 VEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTN 6333 Query: 1272 DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIK 1329 D S + + +V PPK V E +K G L P+ W N ++ Sbjct: 6334 DVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPA 6393 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 K+ IDS A + + + D+G + +N G V + + P P I Sbjct: 6394 SDKYRMTFIDSV-AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPI 6452 Query: 1390 LE-IDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTN 1446 +E + ++ +++ C E T +++Y + Q + ++ I+ KN T I N+ T+ Sbjct: 6453 VETLKNAEVSLEC--ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNF-HTSIHILNVDTS 6509 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 + A NEV SD T K + P L ++T E EL Sbjct: 6510 DIGEYHCKAQNEVG-SDTCVCTVKLK-------EPPRFVSKLNSLTVVAGEPAELQASIE 6561 Query: 1507 GVPQPKVTWYRDGKKL----KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G V W ++ +++ + + T+ EN Y C ND G E Sbjct: 6562 GAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEEN 6621 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + + + VI + VG+ + + G P V WYK+G L + +++ Sbjct: 6622 MATLMVLEPAVIVEKAGPMTVT--VGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKF 6679 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + K S +RI ++R + YT + N G SS + V D+ P Sbjct: 6680 SFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPP 6727 Score = 239 bits (585), Expect = 6e-61 Identities = 195/695 (28%), Positives = 293/695 (42%), Gaps = 36/695 (5%) Query: 1280 KVEVVEFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 K E PP+I D + I+ + L V + P P +W + K Sbjct: 22777 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGE----SLDKA 22832 Query: 1337 SIDSKSAS--LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 SI+S S+ L + V D+G Y L +EN+ G +NV +LD P PP + E+ Sbjct: 22833 SIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTK 22892 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRA 1453 +S+ + WD P G S I Y+VE +E + +V N KT + L+ SY FR Sbjct: 22893 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22952 Query: 1454 YAVNEVDISDASETTEYYKVIKET----KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 A NE I +ET E K + KI V + +++ E E + I G + Sbjct: 22953 LAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIV 23012 Query: 1510 QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSCVVGI 1567 + + T K T ++ A N+ G + V I Sbjct: 23013 EMQTKGSDKWATCATVKVT-----EATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVI 23067 Query: 1568 QQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 + VI + + + V G++ V G P P V W+K+ L+ N + E Sbjct: 23068 AKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTE 23127 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 S++ IK+ R Y ++ +N+AG + + + V DKP P GPV M E++ +S+T+ Sbjct: 23128 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITL 23187 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 W PP DGG + Y +EK + W I A V R C +L CEY FR+ A+ Sbjct: 23188 SWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKAC--RLKTGCEYQFRIAAE 23245 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N G S L SEP V + VP +S+ + W +GGS +I Y + Sbjct: 23246 NRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS-SRDSMEVQWNEPISDGGSRVIGYHL 23304 Query: 1805 EIKQEGK-KWKXXXXXXXXXARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 E K+ W + + L Y+FR+ A N +G P + Sbjct: 23305 ERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 23364 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 PP +P +V T SVTL+W +P +GGS IT YI+E K + W K + Sbjct: 23365 PCDPPGRPEAIIV---TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK-ASFTNI 23420 Query: 1922 VHEHC-IENIKEKDEIIFRISAENTVGV-SLPTES 1954 + H + + E FR+ A N GV S P+ES Sbjct: 23421 IDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSES 23455 Score = 238 bits (583), Expect = 1e-60 Identities = 195/762 (25%), Positives = 325/762 (42%), Gaps = 47/762 (6%) Query: 1219 EIPDETLDVTWYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 +I D + D W + + + K FT+ S + + R C ++ + A+ Sbjct: 19465 KIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQ----VGIGRPAELKE 19520 Query: 1278 KLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKC 1331 +K + + PP+I D + R ++ G + L + P P W + +++K Sbjct: 19521 AIKPKEILEPPEI-DLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRK- 19578 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + + A L I D+G Y L L N G V +NV +LD P P + + Sbjct: 19579 --GQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSD 19636 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYR 1450 + +S ++ W PEN G S + +Y+VE +E D W +V + KT + NL + Y Sbjct: 19637 VTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYY 19696 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FG 1506 FR AVNE ++ + V+ + P + L+ +T L + G Sbjct: 19697 FRVTAVNEYGPGVPTDVPK--PVLASDPLSEPDPPRKLE-VTEMTKNSATLAWLPPLRDG 19753 Query: 1507 GVP-QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHG-----E 1558 G +T YR+ ++ Y YK A N G E Sbjct: 19754 GAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPRE 19813 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 E Q P + E I K G + + A + G P P W K +++ Sbjct: 19814 AEGVYEAKEQLLPPKILMPEQITIK--AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSH 19871 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 + + +S++ IK++ R S Y++ A N++GT + ++ + V D P P+ P + +I Sbjct: 19872 LAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDI 19931 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI-KVADVDRDVETYC-IQKLNENCE 1736 ++ ++ W PL+DGG +T Y +EK + W+ +A V +T C + KL E Sbjct: 19932 DADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASV---TKTSCRVGKLIPGQE 19988 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y+FRV A+N G SE L S +V + VPS ++ + +++ W + +GG Sbjct: 19989 YIFRVRAENRFGISEPLTSPKMVAQFPFGVPS-EPKNARVTKVNKDCIFVAWDRPDSDGG 20047 Query: 1797 SPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTS 1853 SPII Y +E K+ W + Y FRIYA N+ G+S P Sbjct: 20048 SPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 20107 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + +T + PP +P V++ST V+L W P+ +GGS I Y +E + G W Sbjct: 20108 TEYVTARMPVDPPGKPEVIDVTKST---VSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 20164 Query: 1914 KIVTVGGSV--HEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 + T + E+ ++EK + FR A V +S P+E Sbjct: 20165 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSE 20206 Score = 238 bits (583), Expect = 1e-60 Identities = 199/754 (26%), Positives = 323/754 (42%), Gaps = 35/754 (4%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 +TW K ++ T + + + TL I++ +DD +Y + + +E+V Sbjct: 24188 ITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTL 24247 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL- 1345 K + + S ++ + + P + + I++K T D SA++ Sbjct: 24248 D-KPDPPKGPVKFDDVSAESITLSWNP-PLYTGGCQITNYIVQKRDTTTTVWDVVSATVA 24305 Query: 1346 -TIKKVENTDAGI-YKLRL--ENNCGHA-DVEMNVTILD----KPSPPGKPNILEIDSSS 1396 T KV G Y+ R+ EN G + +E + + +P PPG P I S Sbjct: 24306 RTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDS 24365 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAY 1454 + I W EP N G S +I Y +E +E ++ W V I TQ QNL+ Y FR Y Sbjct: 24366 MVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVY 24425 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG-VPQPKV 1513 A N V + AS+ +E Y + P +P+ E GG + + Sbjct: 24426 AENIVGVGKASKNSECY--VARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYI 24483 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEV-ETSCVVG-IQQ 1569 RD + KA++ N Y + IA N G + + S G I Sbjct: 24484 VEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITA 24543 Query: 1570 KPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 K + + + K + G+ + + A + G P P + W + ++E I Sbjct: 24544 KDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKN 24603 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 + +++ +K+ R +Y + ASN AG+ S V +KV D+P PEGPV + ++ E Sbjct: 24604 TDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC 24663 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 ++ W PPL DGG +++ Y +EK E W VA + + + KL E EY+FR++A Sbjct: 24664 SLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVAS-EVVTNSLKVTKLLEGNEYVFRIMA 24722 Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G E LES P+++K +P I +S+ + W + +GGS II Y Sbjct: 24723 VNKYGVGEPLESAPVLMKNPFVLPG-PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 24781 Query: 1804 VEIK-QEGKKW--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 VE + + G +W R+ L+ + Y+FR+ A N G P + Sbjct: 24782 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC 24841 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--V 1918 + P P N + ++T S+TL W +P +GGS I Y++E + W +IVT Sbjct: 24842 DPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEW-QIVTPQT 24900 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 G V I + E E R+ A N VG+ T Sbjct: 24901 GLRVTRFEISKLTEHQEYKIRVCALNKVGLGEAT 24934 Score = 236 bits (578), Expect = 4e-60 Identities = 240/1090 (22%), Positives = 432/1090 (39%), Gaps = 63/1090 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +KP+ V G+ LEC + PE W G E+ D + + + Sbjct: 7571 PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKV---- 7626 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + LKI + +G Y+ N G+++ + + + + PP I LK + G SV Sbjct: 7627 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV-SDRIVPPSFIRKLKDVNAILGASV 7685 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810 +L +V G+ ++ W ++ + + P + ++ L ++ D G+YT A N Sbjct: 7686 VLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANV 7745 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G E SAV+TV+EP P F + V ++ + + P + W++ + Sbjct: 7746 AGSDECSAVLTVQEP-------PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGS 7798 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + P E+ + + EL + V ++SGDY C+ +N AG +S + + E TF Sbjct: 7799 RELVPGESCNISLEDFVTELELFEVQP-LESGDYSCLVTNDAGSASCTTHLFVK-EPATF 7856 Query: 931 VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 VK L + E G ++LE + T +S W ++ IS + I + Sbjct: 7857 VKRLA-DFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 7915 Query: 989 XXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SET 1044 D C++++ Q+ LV P FI L+ E + A L+ +++ + Sbjct: 7916 STIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPE 7975 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEV 1100 + W ++ ++ Y + + ++ L I D GEYSC D S ++ V Sbjct: 7976 IRISWYKEHTKLRSAP-AYKMQFKNNVASLVINKVDHSDVGEYSC-KADNSVGAVASSAV 8033 Query: 1101 TVVE---LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 V++ LPP +L++ G FE + + L V W+KDG ++ ++Q + Sbjct: 8034 LVIKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSF 8093 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA------ILTVEEPSINFTLRLPEFILVPA 1210 L+I D G+Y+C N TA IL+ E F L+ L Sbjct: 8094 VHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALG 8153 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 + + + +TW K I + + TL + K + D +YTC Sbjct: 8154 ESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYA 8213 Query: 1271 LDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKII 1328 + + V+ PP+ + RI + + T P+ W + I Sbjct: 8214 SNIAGKDSCSAHLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI 8273 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 ++ + S A L + + D+G Y N G A ++ + + P KP+ Sbjct: 8274 QESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPH 8333 Query: 1389 ILE-IDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 +E + + +++ C E + T + +Y + + ++ + T I N+ Sbjct: 8334 PIETLKGADVHLEC--ELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAA 8391 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 ++ A N+V S+T +K P K L +I+T ++++L Sbjct: 8392 DIGEYQCKATNDV----GSDTCVGSIALKAP----PRFVKKLSDISTVVGKEVQLQTTIE 8443 Query: 1507 GVPQPKVTWYRD-GKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G V W++D G+ ++ + + EN Y C ND G E Sbjct: 8444 GAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQEC 8503 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + + + I E IK GD + + G P W+K+G +L +D +Y I Sbjct: 8504 FATLSVLEPATIVEKPESIKVT--TGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKI 8561 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE---I 1678 + K S ++I + S S Y+ E N G S +L+V D+ P ++E + Sbjct: 8562 SFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGL 8621 Query: 1679 SRESVTIEWK 1688 S SV +E K Sbjct: 8622 SGSSVVMECK 8631 Score = 235 bits (574), Expect = 1e-59 Identities = 255/1071 (23%), Positives = 432/1071 (40%), Gaps = 75/1071 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KK + S + + P I WL + + D+N+ ++ + Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV---- 6029 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L+I +V G YT A N G L ++ EP Q++E KS+ V + + + Sbjct: 6030 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ----EPAQIVEKAKSVDVTEKDPM 6085 Query: 753 ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L V G P + W K+ K P + + + S I K +D G YT K EN Sbjct: 6086 TLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMK-QDSGQYTFKVEN 6144 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G + A + V ++N PP F + ++ +I + +V+ + S W+++ Sbjct: 6145 DFGSSSCDAYLRV---LDQNI-PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKD 6200 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + IS S ++ L + N++ E D+ +Y C SN AG + +T+ Sbjct: 6201 GKEISTSAKYRLVCHERSVSLEVNNLELE-DTANYTCKVSNVAGDDACSGILTVKEPPSF 6259 Query: 930 FVKHLQKSY---ETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 VK ++ T E K ++ + + KW+ + E+ I EG Sbjct: 6260 LVKPGRQQAIPDSTVEFKAIL---KGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 6316 Query: 987 XXXXXXDVGVIKCIVKDQETS----TMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEI- 1040 G C V + S TML+V E P+F++KL+ + VK D + LE +I Sbjct: 6317 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-PKFVKKLEASKIVKAGDSSRLECKIA 6375 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SC 1096 S VVW R+ + P +KY + + + N S D G++ C ++ SC Sbjct: 6376 GSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSC 6434 Query: 1097 TAEVTVVELP-----PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 + +V V E P P I+ L+N +V+ E EL+ V W+KD +++ S Sbjct: 6435 STKVIVKEPPVFSSFPPIVETLKNAEVS------LECELSGTPPFEVVWYKDKRQLRSSK 6488 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI 1206 ++ + I + D D GEY C EVG+ C + ++EP F +L Sbjct: 6489 KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP-RFVSKLNSLT 6547 Query: 1207 LVPANTDAYLTVEIPD-ETLDVTWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 +V A A L I + + V W K+K VI ++E + TL K + Sbjct: 6548 VV-AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAG 6606 Query: 1265 EYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 +Y C + D + +V P IV+ + G TL P+ + EW Sbjct: 6607 KYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYK 6666 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + K++ + K S +K +SL I VE DAG Y +++NN G + V + D+ P Sbjct: 6667 DGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVP 6726 Query: 1384 PGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQ 1441 P L+ + C E + G+S I V + E T+ +S K T ++ Sbjct: 6727 PSFTRRLKNTGGVLGASCILECKVAGSSPI--SVAWFHE--KTKIVSGAKYQTTFSDNVC 6782 Query: 1442 NLKTNS--SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 L+ NS S Y +++ + E T + P+ K + + P +++ Sbjct: 6783 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVL-----TVQEPPSFVKEPEPLEVLPGKNV 6837 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENR-XXXXXXXXXXXXXXXYKCIAFND 1555 T + G P KV W+R ++L +E+ Y C+ N+ Sbjct: 6838 TFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNN 6897 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G + SC + K + G ++ + G P V W K+G + Sbjct: 6898 AG--QASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6955 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 ++ NI T EKT ++ I + + +Y+ E N AG + + P Sbjct: 6956 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 7006 Score = 233 bits (569), Expect = 5e-59 Identities = 254/1091 (23%), Positives = 436/1091 (39%), Gaps = 71/1091 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 IPP+F+KK K +GS I LEC + I W +EI E + H Sbjct: 5600 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFS----FHDN 5655 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I+ ++ GTYT A N+ G L + KEPP +E +S V Sbjct: 5656 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV----KEPPYFVEKPQSQDVNPNTR 5711 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAEN 809 V L A V G TI W K+NK + + +S DT + L K D G Y + N Sbjct: 5712 VQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSN 5771 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR 868 G A + A + V+ EPP FI + + V G + ++T P ++WY Sbjct: 5772 DVGTATSKATLFVK-------EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL 5824 Query: 869 N-NEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + NEI + + DG ++ V+ +SG Y C A N AG +S + + E Sbjct: 5825 DGNEITAIQKHGISFIDGLATFQISGARVE---NSGTYVCEARNDAGTASCSIELKVK-E 5880 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 TF++ L K E + V LEC+ + T W N +EI + Sbjct: 5881 PPTFIREL-KPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNL 5939 Query: 985 XXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G +CIV ++ ST + +KE P FI+K+++ K A + + Sbjct: 5940 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP-PSFIKKIENTTTVLKSSATFQSTV 5998 Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---- 1095 S + W +D +I+ N Y + L IR+ G Y+C ++ES Sbjct: 5999 AGSPPISITWLKDDQILDEDDNVY-ISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVER 6057 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 C A + V E P +I+ + ++ V + + T E + L V+W KDG +I S + + Sbjct: 6058 CYAFLLVQE-PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSM 6116 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFILV 1208 + + +I D+G+Y+ +V G+S C A L V + +I +FT +L + V Sbjct: 6117 SFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV 6176 Query: 1209 PANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 + ++ ++ + W+K I + K+ L+ + +L + +D YT Sbjct: 6177 -LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYT 6235 Query: 1268 CVLLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 C + + + V+ PP + + S V + P +W + Sbjct: 6236 CKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDV 6295 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + ++ ++ L + V+ + G Y + N+ G + + + P K Sbjct: 6296 ELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKK 6355 Query: 1387 ---PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQN 1442 I++ SS C + + ++++ E+ E+ ++ + I + N Sbjct: 6356 LEASKIVKAGDSSRLEC--KIAGSPEIRVVWFRNEH-ELPASDKYRMTFIDSVAVIQMNN 6412 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 L T S F A N + S ++KE + S P+ + T N ++ L Sbjct: 6413 LSTEDSGDFICEAQNPAGSTSCSTKV----IVKEPPVFSSF--PPI--VETLKNAEVSLE 6464 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 C G P +V WY+D ++L+++K A+ Y C A N+ G Sbjct: 6465 CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS 6524 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 C V +++ P + G+ + A IEG P V W K ++ + E Sbjct: 6525 DTCVCTVKLKEPPRFVSKLNSLTV--VAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE 6582 Query: 1619 -YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 IT E + ++ + + +++ KY + N G TL V + E M Sbjct: 6583 NIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTV 6642 Query: 1678 ISRESVTIEWK 1688 E+ T+E K Sbjct: 6643 TVGETCTLECK 6653 Score = 232 bits (568), Expect = 7e-59 Identities = 185/693 (26%), Positives = 284/693 (40%), Gaps = 30/693 (4%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + R ++ G + + V + P P W ++ +K + + + L I + Sbjct: 21708 ELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENT--ESFTLLIIPECN 21765 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G + + +EN G +NV +LD P P +I S+ + WD P G S Sbjct: 21766 RYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSR 21825 Query: 1412 IIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I Y+VE +E + + K + L Y FR A NE I + +ETTE Sbjct: 21826 ITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE- 21884 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-----RDGKKLKTA 1525 +K ++ SP + +IT G K+T Y R G T Sbjct: 21885 --PVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDG--GSKITGYVIEAQRKGSDQWTH 21940 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV---ETSCVVGIQQKPVITISNEDIKQ 1582 T + ++ +A N G E+ V+ +Q + + I Q Sbjct: 21941 ITTVKG-LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 21999 Query: 1583 K---HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 K K GD V + G P P V W K L+ + N T ++++ I E RS Sbjct: 22000 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSD 22059 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 S Y + A N G +T++V+D P P GP+ E+S + VT W PP +DGG+ ++ Sbjct: 22060 SGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPIS 22119 Query: 1700 KYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y +E + D+ W+++A V R TY +L EY FRV AQN G + S I Sbjct: 22120 NYVVEMRQTDSTTWVELATTVIR--TTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACI 22177 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXX 1817 V VP + +S+ I+W +GGSPI+ Y VE K+ G W+ Sbjct: 22178 VANYPFKVPG-PPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVS 22236 Query: 1818 XXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 + L+ Y+FR+ A N G S P + + + PP +P V Sbjct: 22237 KALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKP---VPL 22293 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 T +VTLKW +PE GG IT+YI+E + + W K +E + + E Sbjct: 22294 NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 22353 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 FR+ A+N G P S + V +P Sbjct: 22354 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAP 22386 Score = 232 bits (568), Expect = 7e-59 Identities = 197/760 (25%), Positives = 319/760 (41%), Gaps = 45/760 (5%) Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 + K R I + D CE T + K+ +L ++ ++++ + ++ G+ + Sbjct: 29250 EYKFRVSAINGAGKGDSCEVTGTI---KAVDRLTAPELDID---ANFKQTHVVRAGASIR 29303 Query: 1307 LLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 L + YQ P P W ++ ++ HT S ++LT++ DAG Y L +EN Sbjct: 29304 LFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSF----STLTVENCNRNDAGKYTLTVEN 29359 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 N G + V +LD P PPG ++ S + WD P G + I +YVVE +E Sbjct: 29360 NSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASR 29419 Query: 1425 TEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 W + + T+ + +L Y FR AVNE + E E + I T + P Sbjct: 29420 RSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG---EPYEMPEPIVAT--EQPA 29474 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXX 1539 + L + T + + ++T Y + K + +A + + Sbjct: 29475 PPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVER 29534 Query: 1540 XXXXXXXXYKCIAFNDHG-----EVETSCVVGIQQ-KPVIT---ISNEDIKQKHKVGDEW 1590 ++ A ND G E +S ++ Q +P I+N+ I K G + Sbjct: 29535 LVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCK--AGSPF 29592 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + I G P P+V W +L+ +ITT + + + +K+ R S +Y + NT Sbjct: 29593 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 29652 Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 AG + VT+ V +P GP+ + +S ES + W P D GG E+T Y +EK E Sbjct: 29653 AGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGT 29712 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 W V + + + L + EY FRV ++N G S+ LES PI+ + VP Sbjct: 29713 TAWQLVNSSVKRTQIK-VTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPF-VPPSA 29770 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXXARIQ 1827 + ++ I W +GGS II Y VE K+ W + ++ Sbjct: 29771 PTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVT 29830 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 L YQFR YA N G S + I + P +P V++ T +V+L W+ Sbjct: 29831 GLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE---VTDVTRSTVSLIWS 29887 Query: 1888 EPESNGGSPITNYIIEFKTVK---GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 P +GGS + YIIE K V W K S + + + E D FR+ A+N Sbjct: 29888 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 29947 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 GV + S+S +PP A L+ R+ G + + Sbjct: 29948 AAGV-ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTI 29986 Score = 231 bits (565), Expect = 2e-58 Identities = 221/892 (24%), Positives = 366/892 (41%), Gaps = 44/892 (4%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVK 1249 VE P + ++ + I+V A + +I L V +W K IE+ + +IS Sbjct: 26711 VEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN 26770 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP-PKIVDYEREYRIKRGSDVT 1306 L ++ C D +Y L + T + V +V++ P P E ++ Sbjct: 26771 HTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 26830 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 + D +IV + T + + S + K+ + I+++ N Sbjct: 26831 WGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKY 26890 Query: 1367 GHADVEMNVTI--LDK---PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 G + +V I LD PSPP I + S+ +CW PE+ G S I Y++E +E Sbjct: 26891 GVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERRE 26950 Query: 1422 IDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 ++ W+ V K + + L+ Y +R YA N +S SET+ + + Sbjct: 26951 KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL 27010 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIF-GGVPQPKVTW-YR-----DGK-KLKTAKAT-YE 1530 SP + + + + +F GG P T Y+ D K +++ + T Y Sbjct: 27011 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 27070 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDE 1589 K A + + +++P+ I +E K K G Sbjct: 27071 ISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 27130 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + +T G P P V+W K L + Y TT +TS + I+ R+ S KYT+ N Sbjct: 27131 FTMTVPFRGRPVPNVLWSKPDTDLRT-RAYVDTTDSRTS-LTIENANRNDSGKYTLTIQN 27188 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 +S+ + +KV D P P + ++++++ES + W P +DGG + Y IEK E Sbjct: 27189 VLSAASLTLVVKVLDTPGPPTN-ITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREAS 27247 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 W+ V + + +Y + L E Y FRV +N G E++ V T P Sbjct: 27248 KKAWVSVTNNCNRL-SYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPE 27306 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK 1828 I +SV +TW E +GGS I+ Y VE ++G+K W + Sbjct: 27307 KLGVTS---ISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSG 27363 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS-QPRNFVVSESTSRS-VTLKW 1886 L N+ Y FR++A N+ G S P + I + L PP +NF R+ LK Sbjct: 27364 LRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKV 27423 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK---DEIIFRISAE 1943 P S G P+ + V K+ + T E+ N+KE D + I+A Sbjct: 27424 DIPIS--GKPLPKVTLSRDGVPLKATMRFNT--EITAENLTINLKESVTADAGRYEITAA 27479 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 N+ G + V L++ P PPT P+ I + V W P++DGG+ + Y + Sbjct: 27480 NSSGTT-KAFINIVVLDR----PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL 27534 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 R+ + +W EV T+ + L+ Y RI A N G+S+ ++S Sbjct: 27535 LKRETSTAVWTEVSATVARTM-MKVMKLTTGEEYQFRIKAENRFGISDHIDS 27585 Score = 230 bits (563), Expect = 3e-58 Identities = 211/770 (27%), Positives = 325/770 (42%), Gaps = 50/770 (6%) Query: 1216 LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 L V++P T VTW+K ++ T + S L I+ +D Y L + Sbjct: 23092 LKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTN 23151 Query: 1273 A--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + ++ L V V++ P + + S +TL P+ + +N+ I++K Sbjct: 23152 SAGEAIETLNVIVLDKPGPPTGPVKMDEVTADS-ITLS---WGPPKYDGGSSINNYIVEK 23207 Query: 1331 ---CKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHAD-VEMNVTILDKP--- 1381 T + + A TIK Y+ R+ EN G + + T+ P Sbjct: 23208 RDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 23267 Query: 1382 -SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 PPG P + S+ + W+EP + G S +I Y +E +E ++ W+ + I +T+ Sbjct: 23268 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKF 23327 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 L+ Y FR A N V I S+ +E Y + P +P I T + Sbjct: 23328 KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECY--VARDPCDPPG--RPEAIIVTRNSVT 23383 Query: 1499 IELT--CIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXY--KC 1550 ++ GG K+T Y KK + KA++ N Y + Sbjct: 23384 LQWKKPTYDGG---SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRV 23440 Query: 1551 IAFNDHGEV-ETSCVVG-IQQKPVITISNEDIKQKHK------VGDEWLVTAVIEGIPPP 1602 IA N G E S G I + + + K+K G+ + V A I G P P Sbjct: 23441 IARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIP 23500 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + W K +L N I + + + + +K+ R S Y ++A N AG SV V +KV Sbjct: 23501 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 23560 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 D+P PEGPV++ ++ E T+ WKPPL DGG ++ Y +E+ E W V D + Sbjct: 23561 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW-TVVDANVQ 23619 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + + KL E EY FR++A N G E LESEP+V K VP + + Sbjct: 23620 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPD-APKAPEVTTVTKD 23678 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRI 1839 S+ + W +GGS I+ Y +E + +EG +W R++ + N Y+FR+ Sbjct: 23679 SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRV 23738 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N G S P + P P N V + T SV L W++P +GG I Sbjct: 23739 SAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQG 23798 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGV 1948 YI+E V WT G + +E + EK E FRI A N GV Sbjct: 23799 YIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGV 23848 Score = 230 bits (563), Expect = 3e-58 Identities = 170/673 (25%), Positives = 288/673 (42%), Gaps = 33/673 (4%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ G + + ++ P P W + ++ L+I + DAG Y Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNY--TQLSIDNCDRNDAGKY 25020 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 L+LEN+ G + V +LD P PP + E+ S + W+ P G + + YV++ Sbjct: 25021 ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID 25080 Query: 1419 YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E + +V + +KT ++NL + Y FR A NE + ET + K + Sbjct: 25081 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPP 25140 Query: 1478 ----KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVTWYRDGKKLKTAKATYEN 1531 K+ V + ++ E E + + G V QPK T K A++ N Sbjct: 25141 SPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGT----EKWSIVAESKVCN 25196 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-----KV 1586 ++ A+N+ G+ + V+G+ +K + Sbjct: 25197 ---AVVTGLSSGQEYQFRVKAYNEKGKSDPR-VLGVPVIAKDLTIQPSLKLPFNTYSIQA 25252 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G++ + + G P P + W K+G L+ N+ ++V+ IKE + KYT+ Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 25312 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 A+N+AGT++ +++ V +KP P GPV E+S + V I W+PP GG +++ Y +EK Sbjct: 25313 ATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 25372 Query: 1707 EPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 + W V A V R T I KL EY FR+ A+N G S L+S+ ++++ Sbjct: 25373 DTTTTTWHMVSATVAR--TTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFK 25430 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA 1824 P I + + + W +GG+ II Y +E K++ W Sbjct: 25431 EPG-PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDT 25489 Query: 1825 RIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + + ++ Y+F++ A N +G P + PP +P V+ T +V Sbjct: 25490 KFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI---TRNNV 25546 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 TLKW +P +GGS IT YI+E K + W K E + + E FR+ A Sbjct: 25547 TLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIA 25606 Query: 1943 ENTVG-VSLPTES 1954 N G S P++S Sbjct: 25607 RNAAGNFSEPSDS 25619 Score = 229 bits (561), Expect = 5e-58 Identities = 207/857 (24%), Positives = 348/857 (40%), Gaps = 45/857 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284 VTW+K IE + + +L +R T D + YT +A + K +KV+V Sbjct: 28917 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28976 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 + P K+V R I G +TL D P +I+ + + ++ Sbjct: 28977 DTPGKVVGPIRFTNIT-GEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEA 29035 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 S T K+ N + +++ N G +D + P PG P I +SI Sbjct: 29036 QSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 29095 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454 + W PE+ G S I Y++E +E +T W+ V + I++T+ + L + Y F Sbjct: 29096 TLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVM 29155 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSP-TVEKPLKNITTEPNEDIELTCIFGGVP---- 1509 A N + AS + K + P TV K T + + GG+ Sbjct: 29156 AENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGY 29215 Query: 1510 --QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG- 1566 + D K+ A+A + R ++ A N G+ ++ V G Sbjct: 29216 IIEMCKADLGDWHKVN-AEACVKTRYTVTDLQAGEEYK--FRVSAINGAGKGDSCEVTGT 29272 Query: 1567 IQQKPVITISNEDI----KQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 I+ +T DI KQ H V G + +G P P +W K + L + Sbjct: 29273 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS--LRAD 29330 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 I T + S + ++ R+ + KYT+ N +G+ S+ T+KV D P P GP+ ++++R Sbjct: 29331 IHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTR 29389 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 S T+ W PL DGG + Y +EK E W +V + + + L E Y FR Sbjct: 29390 GSATLMWDAPLLDGGARIHHYVVEKREASRRSW-QVISEKCTRQIFKVNDLAEGVPYYFR 29448 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 V A N G E E ++ T P S + W + +GGS I Sbjct: 29449 VSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDT---SKSSAVLAWLKPDHDGGSRIT 29505 Query: 1801 DYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 Y +E++Q+G W +++L T Y+FR+ A+N+ G S P + + I Sbjct: 29506 GYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVII 29565 Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTV 1918 + P+ + ++ + +T G P + + ++ K ++ +T Sbjct: 29566 KEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 29625 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 +++ D + ++ ENT GV T S +V + P P T P+E+ V Sbjct: 29626 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVK--TFSVTVVVIGR---PGPVTGPIEVSSV 29680 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 + + SWG P+ GG + Y + R+ T W V V + + L++ Y Sbjct: 29681 SAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS-SVKRTQIKVTHLTKYMEYS 29739 Query: 2039 IRIYARNEIGLSEPLES 2055 R+ + N G+S+PLES Sbjct: 29740 FRVSSENRFGVSKPLES 29756 Score = 229 bits (559), Expect = 8e-58 Identities = 268/1206 (22%), Positives = 488/1206 (40%), Gaps = 88/1206 (7%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 +P F ++ +P V +V G P +ITWF+ I++ + ++ + D++ +L Sbjct: 5319 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFI-QDHLVSL 5377 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I + DAG + C N G + + + + P S ++ A + Sbjct: 5378 QILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS-FIKKIESTSSLRGGTAAFQATL 5436 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF-KGEEIVPDENISVAIESD 687 +P T + + + E +I + E ++A L+ G E+ D ++D Sbjct: 5437 KGSLPITVTWLKDSDEITEDDNIRMTF------ENNVASLYLSGIEVKHDGKYVCQAKND 5490 Query: 688 MHMY-CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIEPLKSMI 745 + CS L +VK + T T AV+ + P L++K +G KE + + Sbjct: 5491 AGIQRCSAL--LSVK--EPATITEEAVSIDVTQGDPATLQVKFSGTKE-------ITAKW 5539 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 + G+ + L ++ + T++ K I+ +K KD G YT Sbjct: 5540 FKDGQELTLGSKYKISVTDTVSILK--------------------IISTEK-KDSGEYTF 5578 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + +N G + A I V + PP F + +++ + I L V + SI Sbjct: 5579 EVQNDVGRSSCKARINV----LDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 5634 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W+++++ IS SE +F L I+ ++ DSG Y C A+N AG + +T+ Sbjct: 5635 WFKDDQEISASEKYKFSFHDNTAFLEISQLEG-TDSGTYTCSATNKAGHNQCSGHLTVK- 5692 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983 E FV+ Q S + V L+ T ++ KW+ + KE+ R + ++ Sbjct: 5693 EPPYFVEKPQ-SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTS 5751 Query: 984 XXXXXXXXXDVGVIKC-IVKDQETST---MLVVKETIPEFIRKLQDFEV-KEKDVAILEV 1038 D G C + D T+T L VKE P+FI+K V + E Sbjct: 5752 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP-PQFIKKPSPVLVLRNGQSTTFEC 5810 Query: 1039 EI-NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 +I + V W DG EI +K+ F + I V + G Y C R+++ Sbjct: 5811 QITGTPKIRVSWYLDGNEITAIQKHGISF--IDGLATFQISGARVENSGTYVCEARNDAG 5868 Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152 TA ++ V+ PP I L+ +V K + E E+T V W K+ EI+ S Sbjct: 5869 TASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKY 5928 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 LT L I CD D GEY C E G+ C+ + ++EP +F ++ V Sbjct: 5929 TLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP-SFIKKIENTTTV 5987 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 ++ + + + +TW K ++++ + + TL IR YTC Sbjct: 5988 LKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTC 6047 Query: 1269 VLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + + +V+ P +IV+ + + +TL P+ +W+ + K Sbjct: 6048 QAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQ 6107 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-K 1386 I ++ S ++ AS I+ V D+G Y ++EN+ G + + + +LD+ PP Sbjct: 6108 IVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 6167 Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTT-EWISVKNITKTQTSIQNLK 1444 + ++D + E + +G+ I + + +EI T+ ++ V + + NL+ Sbjct: 6168 KKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLE 6227 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + + V+ V DA I K + KP + P+ +E I Sbjct: 6228 LEDTANYTC-KVSNVAGDDACSG------ILTVKEPPSFLVKPGRQ-QAIPDSTVEFKAI 6279 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P K+ W++D +L + + + Y C ND G Sbjct: 6280 LKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDS 6339 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + ++ + + P + + + K GD + I G P V+W++N ++L +Y Sbjct: 6340 CTTMLLVTEPPKF-VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYR 6398 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 +T + +VI++ L S + EA N AG++S + V + P P I+ + Sbjct: 6399 MTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKN 6458 Query: 1681 ESVTIE 1686 V++E Sbjct: 6459 AEVSLE 6464 Score = 227 bits (555), Expect = 3e-57 Identities = 209/895 (23%), Positives = 364/895 (40%), Gaps = 51/895 (5%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVKKRT 1252 P+I+ + + I VPA L + I +W+ S + ++E+ T+ + K Sbjct: 30663 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 30722 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 L IR+ T D EYT L + TT ++V+ K +I ++ + ++ Sbjct: 30723 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILD-KPGPPTGPIKIDEIDATSITISWE 30781 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT---IKKVENTDAGIYKLRLE--NNCG 1367 P+ + ++ ++++ +P S S+T K T+ Y R+ N G Sbjct: 30782 P-PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 30840 Query: 1368 HADVEMNVTI-----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 + I + P PP I ++ + + W PE+ G S + Y+VE +E+ Sbjct: 30841 IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEV 30900 Query: 1423 DTTEWISVKNITKTQTSIQN--LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 W+ V + T T ++ L Y R A+N S ++ ++ I Sbjct: 30901 RADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSK--PIVAMDPIA 30958 Query: 1481 SP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKTAKATYENRX 1533 P + P TT + + + + KVT Y D + T Sbjct: 30959 PPGKPQNPRVTDTTRTSVSLAWS-VPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 31017 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG-IQQKPVITISNEDIKQKH------KV 1586 ++ +A N G E + V G ++ ++ + ++ +++ + Sbjct: 31018 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQ 31077 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G +T I+G P P W K G + K I T E + + IKE R S Y + Sbjct: 31078 GGVIRLTIPIKGKPFPICKWTKEGQDIS--KRAMIATSETHTELVIKEADRGDSGTYDLV 31135 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 N G +V + ++V P+ PEGP+ +I SV + W+PP DDGG ++ Y +E+ Sbjct: 31136 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 31195 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALD 1765 E W + R + ++ L EN EY FRV A+N G S+ L+S EP+ KT L+ Sbjct: 31196 EVPKAAWYTIDSRVRGT-SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLN 31254 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXXX 1822 P + SV ++W + +GGS + Y +E K+ KW Sbjct: 31255 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTT 31314 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + L + YQFRI A+N++G S + + + PSQP + + SV Sbjct: 31315 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 31374 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 TL+W +PE +GG I Y +E++ +W K + I + E E FR+ A Sbjct: 31375 TLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFA 31434 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 EN G+S P + ++ ++ T P E++ V + + G A L Sbjct: 31435 ENETGLSRPRRT-AMSIKTKLTSGEAPGIRKEMKDVTTKL-----------GEAAQLSCQ 31482 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 I R + W GK + + K+ + HT + + + G+ + ++E Sbjct: 31483 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 31537 Score = 227 bits (554), Expect = 3e-57 Identities = 206/781 (26%), Positives = 325/781 (41%), Gaps = 48/781 (6%) Query: 1207 LVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 LV A + VEIP VTW K +++ T++ + L I +C D Sbjct: 22001 LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDS 22060 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y L A++ +V+ + IK + V + P ND + Sbjct: 22061 GPYP---LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 22117 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIK---KVENTDAGI---YKLRLENNCGHADVEMNVTI 1377 S + + + T + + A+ I+ K G+ ++++ +N G + I Sbjct: 22118 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACI 22177 Query: 1378 LDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 + P PPG P + + S+ I W EP + G S I+ Y VE +E + W +V Sbjct: 22178 VANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSK 22237 Query: 1433 ITKTQTSIQN--LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 ++ L +Y FR A N S S+ +E ++ I P PL N Sbjct: 22238 ALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSE--PMLALDPIDPPGKPVPL-N 22294 Query: 1491 ITTEP-NEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXX 1545 IT GG K+T Y RD + KA + N Sbjct: 22295 ITRHTVTLKWAKPEYTGGF---KITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTED 22351 Query: 1546 XXY--KCIAFNDHGEV----ETSCVVGIQQKPVITISNEDIKQKH----KVGDEWLVTAV 1595 Y + IA N G + E S + + D+K K K G+ + + A Sbjct: 22352 AAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEAD 22411 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G PPP + W K+G +LE + I + ++ + K+ R S YT+ A+N G + Sbjct: 22412 VSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAK 22471 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 +KV D+P PEGP+ + E++ E + W PPLDDGG ++ Y ++K E W Sbjct: 22472 HIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTN 22531 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 VA + V + KL + EY+FRV+A N G E LESEP++ P Sbjct: 22532 VAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYG-PPDPPKNPE 22589 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSIN 1832 I +S+ + W + +GGS II+Y VE + + G++W R + L+ Sbjct: 22590 VTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEG 22649 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 Y+FRI A N G S P + T+ P P N V +++ S+++ W +P + Sbjct: 22650 HEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYD 22709 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 GGS IT Y++E + W +IVT G + I + E E RI A N+ G+ Sbjct: 22710 GGSEITGYMVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 22768 Query: 1951 P 1951 P Sbjct: 22769 P 22769 Score = 225 bits (550), Expect = 1e-56 Identities = 249/1194 (20%), Positives = 467/1194 (39%), Gaps = 94/1194 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++L P + V ECQV+ + +TW + + P +D+++ + +D +ATL Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATLE 4629 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I +D+GT+ C A N AG +S + + V P S + Sbjct: 4630 IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS----------------------FV 4667 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 + + P++ P G L C+L P + W +E+ + + + Sbjct: 4668 KKVDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSE- 4719 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 ++L IT+VK G+Y+ AVN G S + I KEPP I+ L+ + +G Sbjct: 4720 ---AILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI----KEPPSFIKTLEPADIVRG 4772 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKA 807 + +L +V G I+W K+ K +++ S+ L+ D G Y Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G A T EPP F+ + ++ T+ L A V + S+TW Sbjct: 4833 ANEVGKCGCMA-------THLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 4885 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 + E+I I +F L+I +V G Y C+A N AG + + + E Sbjct: 4886 KGQEVIREDGKIKMSFSNGVAVLIIPDVQISF-GGKYTCLAENEAGSQTSVGELIVK-EP 4943 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 ++ + + G LE + T + KWY + + + I + Sbjct: 4944 AKIIERAE-LIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLK 5002 Query: 986 XXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 D G + ++ ET+ ++ ++ P F + L++ + L+ + Sbjct: 5003 FYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCK 5062 Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ES 1095 I S V W +DG+ I ++Y L I ++D G ++C + Sbjct: 5063 IAGSLPMRVSWFKDGKEI-AASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSK 5121 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 ++ +V+ PP +T+ ++ V G+ + L +RWFK E+ + Sbjct: 5122 DSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYI 5181 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 T + + L++Y D+G Y+C+V G +C+A L V+EP+ F +L L+ Sbjct: 5182 TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA-TFVEKLEPSQLLKK 5240 Query: 1211 NTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC- 1268 L ++ + +TW+ I+++ K + L + +D EY C Sbjct: 5241 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 5300 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 +A S + +V+ P + + + DV LL + P W ++ I+ Sbjct: 5301 AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 5360 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 + + K I SL I K DAG Y+ R+ N G + VT+ + PS Sbjct: 5361 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPS-----F 5415 Query: 1389 ILEIDS-SSINICWDEPENTGNSTIIYYVVEYQEID-TTEWISVKNITKTQTS---IQNL 1443 I +I+S SS+ + T ++ V ++ D TE +++ + + + + Sbjct: 5416 IKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGI 5475 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 + ++ A N+ I S +KE T+ + +I + L Sbjct: 5476 EVKHDGKYVCQAKNDAGIQRCSALLS----VKE----PATITEEAVSIDVTQGDPATLQV 5527 Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 F G + W++DG++L K + + Y ND G Sbjct: 5528 KFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRS 5587 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + + + + +K+ + ++ + ++ G P + W+K+ ++ ++ Sbjct: 5588 SCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEK 5647 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 Y + + T+ + I +L+ + S YT A+N AG + L V + P E P Sbjct: 5648 YKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKP 5701 Score = 224 bits (548), Expect = 2e-56 Identities = 224/984 (22%), Positives = 400/984 (40%), Gaps = 67/984 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P T +KP++ V G LEC + PE W G+E+ D ++ + + Sbjct: 8512 PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV---- 8567 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S LKI NV G Y+ N G+ S L++ + PP LK G SV Sbjct: 8568 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV-SDRTVPPSFTRKLKETNGLSGSSV 8626 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 ++ +V G+P +++W + + T +T ++T+ ++ D G YT A N Sbjct: 8627 VMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEE-SDSGDYTCIATN 8685 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G E SA +TV EP P F+ + + V + + V P S++W++ Sbjct: 8686 MAGSDECSAPLTVREP-------PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKG 8738 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + P + + + EL + +VD+ SG+Y C+ SN AGK+S + I Sbjct: 8739 SSELVPGDRCNVSLEDSVAELELFDVDTS-QSGEYTCIVSNEAGKASCTTHLYIKAP-AK 8796 Query: 930 FVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 FVK L Y E+GK +ILE + T +S W N ++ I + Sbjct: 8797 FVKRLN-DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIP 8855 Query: 988 XXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NS 1042 D G C +++ S +++ E P F+++L+ +V D A L+ ++ + Sbjct: 8856 SSTVEDAGQYNCYIENASGKDSCSAQILILEP-PYFVKQLEPVKVSVGDSASLQCQLAGT 8914 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTA 1098 V W + ++P Y R ++ L ++D GEY C + S + Sbjct: 8915 PEIGVSWYKGDTKLRPTTT-YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAST 8973 Query: 1099 EVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 +TV E LPP +L++ + G F+ ++ + + V W+KDG ++ S ++Q + Sbjct: 8974 FLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTS 9033 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVP 1209 L I+ D AG+YSC N S ILT + F +RL V Sbjct: 9034 FLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV 9093 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 + + + + V+W K I K+ + L + K + D +YTC Sbjct: 9094 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 9153 Query: 1270 LLDA----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP-NDEWIVN 1324 ++ T +L ++ PP E + + L A QP W N Sbjct: 9154 AVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN 9213 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 + I+ + + + + + L ++K DAG+Y ++ N+ G A ++ I + PP Sbjct: 9214 NIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 9273 Query: 1385 G-KPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 ++ + S G+ I I ++ +EI ++ S + T++ Sbjct: 9274 VFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS--FASGTAVLE 9331 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN----ITTEPN-- 1496 L+ + Y +++ S+TT+ IK+ +P +K + +EP Sbjct: 9332 LRDVAKADSGDYVCKASNVA-GSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSI 9390 Query: 1497 ---EDIELTCI--FGGVPQPKVTWYRDG-KKLKTAKATYENRXXXXXXX----XXXXXXX 1546 E T I GG P P V W + ++L + ++ Sbjct: 9391 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 9450 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQK 1570 Y+C+AFN+HGE+E++ + + ++ Sbjct: 9451 LYRCVAFNEHGEIESNVNLQVDER 9474 Score = 224 bits (547), Expect = 2e-56 Identities = 238/963 (24%), Positives = 395/963 (41%), Gaps = 77/963 (7%) Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200 +D E+QF+ ++ ++G + + ++ + + S VG C + P + ++ Sbjct: 16996 RDVEELQFT--VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC------QRPDMPPSI 17047 Query: 1201 RLPEFILVPANTDAYLTVEIPDETLD-VTWYK--------KKSVIEDTEKFTLISDVKKR 1251 L EF+ V T+ + +I +TW+K K+ V+ DT L+ D Sbjct: 17048 DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD-DTC 17106 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 TL+I + D YT ++ T ++++ V+ P V ++ +TL Sbjct: 17107 TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVG-PIKFESVSADQMTL-- 17163 Query: 1310 DYQAFPQPND--EWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDAGIYKLRLE 1363 FP +D I N I K+ + K S + K + TI K+ ++++ + Sbjct: 17164 --SWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 17221 Query: 1364 NNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 N G ++ E + P P KP + + +S+ + W+EPE G S + Y +E Sbjct: 17222 NKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLE 17281 Query: 1419 YQEIDTTEWISV-KNITKTQT-----SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 ++ + W V ++ K T + L S Y+FR YA+N + AS ++ Sbjct: 17282 MKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSD--P 17339 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIF---GGVPQPKVTWYRDGKKLKTAKATY 1529 I P P T+ + D+E + G + Y++ K + K Sbjct: 17340 ATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKD 17399 Query: 1530 ENRXXXXXXXXXXXXXXXYK----CIAFNDHGEV-ETSCVVGIQQKPVITISNEDIKQKH 1584 + YK + GE E + V+ ++ + V D + Sbjct: 17400 KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 17459 Query: 1585 KV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 ++ G + A + G PPP V W N L +E I T +S + IK +RSH Sbjct: 17460 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP--QEATIETTAISSSMVIKNCQRSHQ 17517 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 Y++ A N AG + + V D P P + ++ ES + W P DDGG +T Sbjct: 17518 GVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITN 17577 Query: 1701 YAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758 Y IEK E D W V V R T +Q L + Y FR+ A+N +G +E SE + Sbjct: 17578 YVIEKRESDRRAWTPVTYTVTRQNAT--VQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 17635 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818 VI+ + VP N +V +TW P + +GGS II+Y +E + G + Sbjct: 17636 VIREPITVPERPEDLEVKEVTKN-TVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVT 17694 Query: 1819 XXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 +R ++ L TY++R+ A N +G P IT L PP+ +F Sbjct: 17695 NDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDK 17754 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK-- 1933 + T S P ++ + V T I T ++ +E IK K Sbjct: 17755 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL---ALEKIKAKRS 17811 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 D + + EN+ G S Q +++ P PP P+ V + ++ SW P D Sbjct: 17812 DSGKYCVVVENSTG-SRKGFCQVNVVDR----PGPPVGPVSFDEVTKDYMVISWKPPLDD 17866 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 GG+ + Y I ++V K +WM V T + L E Y+ RI+A N G+S+PL Sbjct: 17867 GGSKITNYIIEKKEVGKDVWMPVTSASAKT-TCKVSKLLEGKDYIFRIHAENLYGISDPL 17925 Query: 2054 ESD 2056 SD Sbjct: 17926 VSD 17928 Score = 223 bits (545), Expect = 4e-56 Identities = 192/796 (24%), Positives = 337/796 (42%), Gaps = 44/796 (5%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVK 1249 +E P I+ + V A ++ + + I + L + V ++ T +F + Sbjct: 27398 LEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE 27457 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 T+ +++ D Y ++ TTK + +V + I ++ ++ + Sbjct: 27458 NLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLD-RPGPPTGPVVISDITEESVTL 27516 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI---YKLRLENN 1365 ++ + N ++K+ T + S + + T+ KV G ++++ EN Sbjct: 27517 KWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENR 27576 Query: 1366 CGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 G +D + + K P PP P + + SI + W EP + G S ++ Y +E + Sbjct: 27577 FGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMK 27636 Query: 1421 EIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + ++ W I T + + Y FR YA N + S +E V+ Sbjct: 27637 DRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSE--PVLAIDA 27694 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXX 1534 + P + + + GG K+T Y RD + KA++ N Sbjct: 27695 CEPPRNVRITDISKNSVSLSWQQPAFDGG---SKITGYIVERRDLPDGRWTKASFTNVTE 27751 Query: 1535 XXXXXXXXXXXXXYKCIAF--NDHGEVET-SCVVG------IQQKPVITISNEDIKQ-KH 1584 Y+ F N G + S VVG PVI + E + K+ Sbjct: 27752 TQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKY 27811 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G + A I G P P + WYK+ +L+ + + + I IK+ R +S Y Sbjct: 27812 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 27871 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 ++ N G++S + +++ DKP P GP+ + ++ E +T+ W+PP DDGG ++T Y +E Sbjct: 27872 LKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVE 27931 Query: 1705 KHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 K E W V++ ++ + T K+ + EY+FRV A N G E LES+ +V K A Sbjct: 27932 KRETSRVVWSMVSEHLEECIIT--TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 27989 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXX 1821 P I S+ + W +GGS I Y +E K++ K W Sbjct: 27990 FVTPG-PPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLE-KRDKKSLGWFKVLKETI 28047 Query: 1822 XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKI-TIGKTLTPPSQPRNFVVSEST 1878 R + L+ N+ YQ+R+ A N G P++ + + PP P +++ST Sbjct: 28048 RDTRQKVTGLTENSDYQYRVCAVNAAGQG-PFSEPSEFYKAADPIDPPGPPAKIRIADST 28106 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEII 1937 S+TL W++P +GGS +T Y++E + + + WT + T G E+ + N+K Sbjct: 28107 KSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYY 28166 Query: 1938 FRISAENTVGVSLPTE 1953 FR+SA N G P E Sbjct: 28167 FRVSAVNCAGQGEPIE 28182 Score = 223 bits (544), Expect = 6e-56 Identities = 198/807 (24%), Positives = 354/807 (43%), Gaps = 56/807 (6%) Query: 1191 VEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245 ++EP I T L L+ + T+++P VTW ++ +++T++ ++ Sbjct: 29565 IKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSIT 29624 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSD 1304 + + TL ++ D Y L + V VV P V E + S Sbjct: 29625 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIE--VSSVSA 29682 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP--SIDSKSASLTIKKVENTDAGIYKLRL 1362 + ++ + I N + K+ T ++S IK T Y R+ Sbjct: 29683 ESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRV 29742 Query: 1363 --ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 EN G + + I+ + PS P +P + + +++++I W+EP + G S II Y Sbjct: 29743 SSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGY 29802 Query: 1416 VVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 VE +E +T W+ + + + + L Y+FR YA+N +S ASE + + Sbjct: 29803 WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR--PI 29860 Query: 1474 IKETKIQSP-------TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 + + + +P + I + P D + + + V+ DG+ LK Sbjct: 29861 MAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLK-CN 29919 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV----ETSCVVGIQQKPVITISNEDIKQ 1582 T + ++ +A N G + E++ V + + + D + Sbjct: 29920 YTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARL 29979 Query: 1583 KH-----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 + G + ++ A + G P P++IW K +L+ ++ ++ K + IK R Sbjct: 29980 HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDR 30039 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 S S KYT+ N +GT +V V +KV D P P G + + +++E T+ W P +DGG E Sbjct: 30040 SDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTLAWSLPQEDGGAE 30098 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP 1757 +T Y +E+ E W+ + + + +Y + +L +N EY+FRV A N G +ESEP Sbjct: 30099 ITHYIVERRETSRLNWV-IVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEP 30157 Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KW-- 1813 IV + + +PS E + I W E +GG+ I +Y V+ K+E K +W Sbjct: 30158 IVARNSFTIPSPPGIPEEVGT-GKEHIIIQWTKPESDGGNEISNYLVD-KREKKSLRWTR 30215 Query: 1814 -KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK---TLTPPSQP 1869 ++ L YQFR+ A N G S P + + I+ + T PPS P Sbjct: 30216 VNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAP 30275 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCI 1927 R V ++T S++L WT+P +GG+ I Y++E + W ++ T ++ E + Sbjct: 30276 R---VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHT-NATIRNTEFTV 30331 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTES 1954 ++K + FR++A N G+S +ES Sbjct: 30332 PDLKMGQKYSFRVAAVNVKGMSEYSES 30358 Score = 221 bits (540), Expect = 2e-55 Identities = 185/703 (26%), Positives = 304/703 (43%), Gaps = 40/703 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV----KNITK 1435 KPSPP P ++ +S+++ W P + G S I+ Y+VEYQ++ EW ++ + Sbjct: 18039 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 18098 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 T+ + L+ +Y+FR AVN SD + E V+ + +++ P + N+ E Sbjct: 18099 TKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPE--PVLVKDRLEPPELILDA-NMAREQ 18155 Query: 1496 N----EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXY 1548 + + + L+ I GVP PKVTW ++ + T KA + Y Sbjct: 18156 HIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPT-KARIDVTPVGSKLEIRNAAHEDGGIY 18214 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWY 1607 N G S V + KP E + +K W G + Sbjct: 18215 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 18274 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYD 1664 + + T+K+K+ K L + + + A N G T +K D Sbjct: 18275 RRDVASAQWSPLSATSKKKSHFA--KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 18332 Query: 1665 KPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 P P GP + ++ + V++ W P DGG +T Y +E E WIK V Sbjct: 18333 -PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVT- 18390 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 ++E + L + Y FRV A+N VG + PI + L PS + Sbjct: 18391 NLECV-VTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVV 18449 Query: 1782 ESVYITWFPSEKNGGS-PIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 ++ FP+ G P + EIK + + + I+ T ++ Sbjct: 18450 KAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSVLTIKNCLRRDTGEY 18508 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 +I N G+ T +T+ PP+ P N + + T +T+ W P+ +GGSP+ Sbjct: 18509 QITVSNAAGSK---TVAVHLTVLDVPGPPTGPINIL--DVTPEHMTISWQPPKDDGGSPV 18563 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 NYI+E + + +W +V+ G S + I ++++ E +FR+ AEN +GV P +S Sbjct: 18564 INYIVEKQDTRKDTWG-VVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPT 18622 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + + PSPP P+ + + N SW P+ DGG+P+ GY + R+VT W+ V Sbjct: 18623 VAKHKFSPPSPPGKPV-VTDITENAATVSWTLPKSDGGSPITGYYMERREVTGK-WVRVN 18680 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 K + LKF + L E +TY R++A N GLS+P S +P K Sbjct: 18681 KTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIK 18723 Score = 220 bits (538), Expect = 3e-55 Identities = 238/1072 (22%), Positives = 437/1072 (40%), Gaps = 75/1072 (6%) Query: 633 PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHM 690 P TF +K + +Q + +G L C++ P I W EI ++ +ES Sbjct: 5225 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVES---- 5280 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 +VL++T+V G Y A N G ++ + KE P + K + V + Sbjct: 5281 -TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV----KESPYFTKEFKPIEVLKEY 5335 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV-KDEGVYTLKAE 808 V+L A+V G P ITW K+N +++ K+ H +++ K V D G Y + Sbjct: 5336 DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVT 5395 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G + SA +T+ EPP FI + + + GT A + + ++TW + Sbjct: 5396 NEVGSSICSARVTLR-------EPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLK 5448 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 +++ I+ + I F+ L ++ ++ + D G Y C A N AG A +++ E Sbjct: 5449 DSDEITEDDNIRMTFENNVASLYLSGIEVKHD-GKYVCQAKNDAGIQRCSALLSVK-EPA 5506 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDHR----------EI 975 T + S + +G L+ + S T ++ KW+ + +E++ G ++ +I Sbjct: 5507 TITEE-AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKI 5565 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE-VKEKDVA 1034 I + DVG C K + L++ P F +KL+ + +K + Sbjct: 5566 ISTEKKDSGEYTFEVQNDVGRSSC--KARINVLDLIIP---PSFTKKLKKMDSIKGSFID 5620 Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 + + S + W +D + I + KY F + L I D G Y+C ++ Sbjct: 5621 LECIVAGSHPISIQWFKDDQEISASE-KYKFSFHDNTAFLEISQLEGTDSGTYTCSATNK 5679 Query: 1095 S----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQF 1148 + C+ +TV E PP + + Q+Q VN + + L G A ++WFKD E+ Sbjct: 5680 AGHNQCSGHLTVKE-PPYFVEKPQSQDVNPNTRVQLK-ALVGGTAPMTIKWFKDNKELHS 5737 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204 + D L+++ D+G Y C +VG + A L V+EP P Sbjct: 5738 GAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPV 5797 Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 +L + + + V+WY + I +K + T I ++ Sbjct: 5798 LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 5857 Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y C + T +E+ V+ PP + + + + SDV L + P W+ Sbjct: 5858 TYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLK 5917 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 N++ I+ K + +L I K + +D G Y+ + N G V + + PS Sbjct: 5918 NNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSF 5977 Query: 1384 PGK-PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SI 1440 K N + SS + G+ I I ++ + Q +D + + + + T I Sbjct: 5978 IKKIENTTTVLKSSATF---QSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQI 6034 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 +++ S R+ A NE + E + +++E + VEK K++ + + Sbjct: 6035 RSVDNGHSGRYTCQAKNESGV----ERCYAFLLVQE---PAQIVEK-AKSVDVTEKDPMT 6086 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR-XXXXXXXXXXXXXXXYKCIAFNDH 1556 L C+ G P+ KV W +DGK++ ++ ++EN Y ND Sbjct: 6087 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G + + + + + + + KV G + + G P W+K+G ++ Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +Y + E++ + + L+ ++ YT + SN AG + L V + PS Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPS 6258 Score = 220 bits (537), Expect = 4e-55 Identities = 207/803 (25%), Positives = 340/803 (42%), Gaps = 53/803 (6%) Query: 1202 LPEFI-LVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 LP+ L N++ L + I + V+W K + + + ++ S TLI+ C Sbjct: 20914 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQ 20973 Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 + D +YT L + T + + + V P I ++ +TL A P+ + Sbjct: 20974 KSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK---WAPPKDD 21030 Query: 1319 DEWIVNSKIIKK--CKHTKPSIDSKSASLTIKKVENTDAGI---YKLRLENNCGHADVEM 1373 + + I++K + K + + T +V G+ +++ EN G + Sbjct: 21031 GGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLK 21090 Query: 1374 NVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 + I+ D P P PNI+++ S+++ W +P+ TG S I Y +E++E ++ W Sbjct: 21091 SEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLW- 21149 Query: 1429 SVKNITKTQTSIQNLKTNS-----SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 K KT +++ K Y FR A+N + S +E V+ I P Sbjct: 21150 --KRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSE--PVVALDPIDPPG 21205 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXX 1539 + + NIT I + G K+T Y RD KA + N Sbjct: 21206 KPEVI-NITRNSVTLIWTEPKYDG--GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTV 21262 Query: 1540 XXXXXXXXY--KCIAFNDHGEV-------ETSCVVGIQQKPVITISNEDIKQ--KHKVGD 1588 Y + A N G + ET + P I + + IK K GD Sbjct: 21263 TDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVL-DPTIKDGLTIKAGD 21321 Query: 1589 EWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 ++ A+ I G P P+ W K G + IT+ +S++ IK R + +YTI A Sbjct: 21322 TIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITA 21381 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 +N GT V + V D P P GPV + +S E T+ W PPL+DGG + Y +EK E Sbjct: 21382 TNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRE 21440 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 W V++ D + KL + EY+FRV A N G E ++SEP+ + P Sbjct: 21441 TSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPP 21499 Query: 1768 SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR- 1825 N + ++W +GGS I Y VE ++ + +W R Sbjct: 21500 GPPEKPEVSNVTKNTAT-VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 21558 Query: 1826 -IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 + L +TY+FR+ A N G P + D + + PP P N V+++T +S +L Sbjct: 21559 KVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASL 21618 Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAE 1943 W +P +GG IT Y++E + V ++W K T + + + +++ K++ FRISA Sbjct: 21619 AWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAI 21678 Query: 1944 NTVGVSLPTESQSVRLEKHATVP 1966 N GV P V + + P Sbjct: 21679 NDAGVGEPAVIPDVEIVEREMAP 21701 Score = 219 bits (534), Expect = 9e-55 Identities = 226/1068 (21%), Positives = 428/1068 (40%), Gaps = 58/1068 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F KKP +G+D+ LEC L P ++W E+ + + E+ + Sbjct: 8325 PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSEN----FL 8380 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + + I NV G Y A N G + + +K PP+ ++ L + G+ V Sbjct: 8381 TSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKA----PPRFVKKLSDISTVVGKEV 8436 Query: 753 ILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809 L + G ++ W K+ + V+ + +I L+ +V+ + G YT + +N Sbjct: 8437 QLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 8496 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G+ E A ++V EP + + + I V T L V P S W+++ Sbjct: 8497 DAGMQECFATLSV-------LEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKD 8549 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV- 928 + ++ +F + L I NV + DSG Y N GK S A + + V Sbjct: 8550 GKELTSDNKYKISFFNKVSGLKIINV-APSDSGVYSFEVQNPVGKDSCTASLQVSDRTVP 8608 Query: 929 -TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 +F + L+++ G +V++EC+ S +S W+H EIS + Sbjct: 8609 PSFTRKLKETNGLS-GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 8667 Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEI 1040 D G CI + E S L V+E P F++K +V +V + Sbjct: 8668 VNMLEESDSGDYTCIATNMAGSDECSAPLTVREP-PSFVQKPDPMDVLTGTNVTFTSIVK 8726 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + V W + + P ++ + + +L + + GEY+CI+ +E+ A Sbjct: 8727 GTPPFSVSWFKGSSELVPG-DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 8785 Query: 1101 TV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 T ++ P + + RL + + KG E T + V W K+G + S +T Sbjct: 8786 TTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITT 8845 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 K L+I ++DAG+Y+C + G C+A + + EP F +L E + V Sbjct: 8846 TEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPY-FVKQL-EPVKVSVGD 8903 Query: 1213 DAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-- 1269 A L ++ + V+WYK + + T + + TL+ + +D EY C Sbjct: 8904 SASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAE 8963 Query: 1270 --LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + + ++T L V+ + PP R+ + G V + W + K Sbjct: 8964 NSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKP 9023 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 +K + + S +A+L I K + + AG Y N G A + + + +PP Sbjct: 9024 LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFD 9083 Query: 1388 -NILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNLK 1444 + +D+ E TG I + + + +EI + + + + ++ + Sbjct: 9084 IRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVD 9143 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 S ++ YAVNEV + IKE I ++ + + +L Sbjct: 9144 KGDSGQYTCYAVNEVGKDSCTAQLN----IKERLIPPSFTKRLSETVEETEGNSFKLEGR 9199 Query: 1505 FGGVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE 1560 G V WY++ +++ + T++N Y C ND G Sbjct: 9200 VAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSAL 9259 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 + + I++ + ++ + E++ ++ ++G P + W K G +++ Sbjct: 9260 CTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRC 9319 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + + T+V+ ++++ ++ S Y +ASN AG+ + + + + DKP+ Sbjct: 9320 SFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPA 9367 Score = 218 bits (533), Expect = 1e-54 Identities = 225/903 (24%), Positives = 364/903 (40%), Gaps = 84/903 (9%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 VEK G T EC V G P WF+ + +++ + + V+ L I Sbjct: 8516 VEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFN-KVSGLKIIN 8574 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 V P D+G ++ +N G S T L V S+ TV Sbjct: 8575 VAPSDSGVYSFEVQNPVGKDSCTASLQV--------SDRTV------------------- 8607 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F++K K GS +++EC++ P ++W +G EI + + C Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT---C 8664 Query: 693 SVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + L + +++ G YT +A N G E S P+ + +EPP ++ M V G Sbjct: 8665 A-LTVNMLEESDSGDYTCIATNMAGSDECSAPLTV------REPPSFVQKPDPMDVLTGT 8717 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808 +V ++ V G P +++W K + + + S+ L+ V G YT Sbjct: 8718 NVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS 8777 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G A + + ++ P + F+ R + ++++ + L T P S+TW + Sbjct: 8778 NEAGKASCTTHLYIKAPAK-------FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKK 8830 Query: 869 NNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 N ++PS+ IT +E+ + V+ D+G Y C N++GK S A++ I +E Sbjct: 8831 NGINVTPSQRCNITTTEKSAILEIPSSTVE---DAGQYNCYIENASGKDSCSAQILI-LE 8886 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 FVK L+ + G + L+CQ + T + WY ++ ++ Sbjct: 8887 PPYFVKQLE-PVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945 Query: 985 XXXXXXXXDVGVIKC----IVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEV 1038 D G C V + ST L V+E P F R+L+D + + + Sbjct: 8946 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC 9005 Query: 1039 EIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRD 1093 I+ SE V W +DG+ +K N + L I T G+YSC + Sbjct: 9006 AISGSEPISVSWYKDGKPLKDSPN-VQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 9064 Query: 1094 ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 S +A + + E PP RL G A FE +T + V W KD EI+ Sbjct: 9065 ASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGG 9124 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLPE 1204 Q++ L + D D+G+Y+C EVG CTA L ++E I +FT RL E Sbjct: 9125 KYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSE 9184 Query: 1205 FILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + L + + + V WYK I+ T + L +RK +D Sbjct: 9185 TVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDA 9244 Query: 1264 CEYTC-VLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319 YTC V DA S T+ + ++ + PP + + G V L Q Sbjct: 9245 GLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRI 9304 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +W+ + IK S S +A L ++ V D+G Y + N G + VTI D Sbjct: 9305 QWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKD 9364 Query: 1380 KPS 1382 KP+ Sbjct: 9365 KPA 9367 Score = 217 bits (531), Expect = 2e-54 Identities = 198/748 (26%), Positives = 332/748 (44%), Gaps = 48/748 (6%) Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD--VEMNVTILDK---PSPPGKPNILE 1391 S +K+ K +E D I+++ EN G +D V ++ D+ P P +P + E Sbjct: 17891 SASAKTTCKVSKLLEGKDY-IFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17949 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT---KTQTSIQNLKTNSS 1448 + S + W++P + G I Y++E +E + W V T+ + +L Sbjct: 17950 VTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQ 18008 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI---- 1504 Y FR A NE+ I D S ++ V + I P+ + I T N ++LT Sbjct: 18009 YEFRVSAENEIGIGDPSPPSK--PVFAKDPIAKPSPPVNPEAIDTTCNS-VDLTWQPPRH 18065 Query: 1505 FGG--VPQPKVTWYRDG-KKLKTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHGEV 1559 GG + V + + G ++ + A T E+ YK +A N GE Sbjct: 18066 DGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES 18125 Query: 1560 ETSCV---VGIQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 + + V V ++ + P + + +++H KVGD ++A+I+G+P P+V W K Sbjct: 18126 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 18185 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++T S + I+ Y++ N AG+ +V V + V DKP P Sbjct: 18186 APTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR-D 18242 Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732 + + EI ++S + WK PLDDGG +T Y +E+ + + +W ++ + +++ + LN Sbjct: 18243 LEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK-KSHFAKHLN 18301 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFP 1790 E +Y+FRV A+N G +E+ P IK ALD P +D V + W Sbjct: 18302 EGNQYLFRVAAENQYGRGPFVET-PKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 18359 Query: 1791 SEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL 1849 +++GGSPI Y VE ++EG + W + L TY+FR+ A N +G L Sbjct: 18360 PDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGL 18419 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 P T+ I + L PPS + + E T+++ P + + + Sbjct: 18420 PDTT-IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEI 18478 Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 K + T S I+N +D ++I+ N G +++ +V L VP Sbjct: 18479 KTDEHYTVETDNFS-SVLTIKNCLRRDTGEYQITVSNAAG----SKTVAVHLTV-LDVPG 18532 Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027 PPT P+ I V + SW P+ DGG+P++ Y + +D K W V T K Sbjct: 18533 PPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKT-KLK 18591 Query: 2028 IRDLSENHTYMIRIYARNEIGLSEPLES 2055 I L + Y+ R+ A N+IG+ PL+S Sbjct: 18592 IPHLQKGCEYVFRVRAENKIGVGPPLDS 18619 Score = 217 bits (531), Expect = 2e-54 Identities = 170/693 (24%), Positives = 291/693 (41%), Gaps = 26/693 (3%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP P +++ SI++ W +P G + I+ YV+E QE DT +W V I T+ Sbjct: 30269 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 30328 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPN 1496 ++ +LK Y FR AVN +S+ SE+ + ++ +I + LK +T Sbjct: 30329 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAG 30388 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFN 1554 + L G P P +TW + G L + T E+ Y A N Sbjct: 30389 ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAEN 30448 Query: 1555 DHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 G+ + +V + P ++ +++ + V W + + G P I K Sbjct: 30449 QSGKKSATVLVKVYDTPGPCPSVKVKEVS-RDSVTITWEIPTIDGGAPVNNYIVEKREAA 30507 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + K +TTK ++ RI L + + N G T P P Sbjct: 30508 MRAFK--TVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVP 30565 Query: 1673 VIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730 + ++++ +VT+ W+ PL DGG LT Y +E + RW+KV + V + + Sbjct: 30566 AKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTS 30625 Query: 1731 LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDNESVYITWF 1789 LNE +Y+FR+ AQN G SE E+ V L V P+ I + Sbjct: 30626 LNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVEL 30685 Query: 1790 PSEKNGGSPIID---YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 G P + +E ++ I++ +I T ++ + +N G Sbjct: 30686 VIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTG 30745 Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 T+ + K+ I PP+ P + E + S+T+ W PE +GG+P++ Y++E + Sbjct: 30746 TT---SETIKVIILDKPGPPTGP--IKIDEIDATSITISWEPPELDGGAPLSGYVVEQRD 30800 Query: 1907 VKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965 W + +V S + + E +E +FR++A N G+ +S+ + + Sbjct: 30801 AHRPGWLPVSESVTRSTFK--FTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRI 30858 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP L+I V + + +W PE DGG+ + GY + ++V W+ V KV V + Sbjct: 30859 PGPPET-LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 30917 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + L+E Y R+ A N G +P +P Sbjct: 30918 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30950 Score = 217 bits (530), Expect = 3e-54 Identities = 236/1040 (22%), Positives = 413/1040 (39%), Gaps = 74/1040 (7%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 LPP+I+ Q + G K E + K +W K E+ S+H+ + L Sbjct: 19825 LPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 19883 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVPANTDAY-LTVEIP 1221 I D D+G YS NS T ++ ++ P F + + DA L+ IP Sbjct: 19884 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19943 Query: 1222 --DETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AK 1274 D ++T Y +K + + T ++ V K + + K + + + ++ Sbjct: 19944 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 20003 Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 T K+ V +FP + + R+ + + + V + I+ I +K +++ Sbjct: 20004 PLTSPKM-VAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNS 20062 Query: 1335 KPSIDSKSASLTIKKVENTDAGI-----YKLRLE--NNCGHADVEMN---VTILDKPSPP 1384 + K+ ++ E AG+ Y R+ N G + VT PP Sbjct: 20063 LLWV--KANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPP 20120 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKTQTSI 1440 GKP ++++ S++++ W P++ G S II Y VE ++ +W+ I + + + Sbjct: 20121 GKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA 20180 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDI 1499 L+ + Y+FRA A V+IS SE ++ ++ E + +K++ T + ++ Sbjct: 20181 TGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNV 20240 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 L G P P V+W +DG LK A+ A N Y A N Sbjct: 20241 CLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENS 20300 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G + + + KP S +K D A++ PP E + N + + Sbjct: 20301 SGSKSATIKLKVLDKPGPPAS---VKINKMYSDR----AMLSWEPPLEDGGSEITNYIVD 20353 Query: 1616 DKEYN------ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYD 1664 +E + ++ + +++L H ++ I A N G + + YD Sbjct: 20354 KRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYD 20413 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 P + + PVI I+++ +T+ WKPP DDGG +T Y +EK E W KV Sbjct: 20414 PPGRCDPPVISN-ITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIER 20472 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 T L E EY FRV A N G + ++ P SV Sbjct: 20473 TLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSV 20532 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQ-EGKKW---KXXXXXXXXXARIQKLSINTTYQFRIY 1840 ++W +GGSPII Y VE+K+ + W + L +T YQFR+Y Sbjct: 20533 SLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVY 20592 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPIT 1898 A N+IG S P DK L PP + + ++ VT++ P P Sbjct: 20593 AVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKI 20652 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 + ++ + I + C EN+ + D + ++ EN+ G + + Sbjct: 20653 TWSKPNVNLRDRIGLDIKSTDFDTFLRC-ENVNKYDAGKYILTLENSCG-----KKEYTI 20706 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + K P PP + ++ + + +W P DGG+P++ Y + RD + W V Sbjct: 20707 VVKVLDTPGPPVN-VTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-T 20764 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTE 2078 + + F + +L E +Y R++A NE G+ +P E+ + K A + PG + Sbjct: 20765 TECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVK--------ASQTPGPVVD 20816 Query: 2079 VXXXXXXXXXXXXXWLREHN 2098 + W + H+ Sbjct: 20817 LKVRSVSKSSCSIGWKKPHS 20836 Score = 217 bits (529), Expect = 4e-54 Identities = 266/1201 (22%), Positives = 467/1201 (38%), Gaps = 92/1201 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F++K+ T S+ F+ V G P ITW + D Q+ +DDNV Sbjct: 5975 PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLK---------DDQILDEDDNVYI-- 6023 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 F S L + + + H T A +L Sbjct: 6024 --------------------SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 6063 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 P +K K+ V E + LEC + PE + WL G++IVP S++ E+++ Sbjct: 6064 VQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVA 6123 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 + +I +V K G YT N G +S L++ + PP + L M G Sbjct: 6124 SF----RIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV-LDQNIPPSFTKKLTKMDKVLG 6178 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITI-LKPKKVKDEGVYTLKA 807 S+ + +V G+ + W K+ K + + + S+++ + +++D YT K Sbjct: 6179 SSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 6238 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G S ++TV+EP +P R Q I T++ A + P I W+ Sbjct: 6239 SNVAGDDACSGILTVKEPPSFLVKP----GRQQAI---PDSTVEFKAILKGTPPFKIKWF 6291 Query: 868 RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +++ E++S + +G L + +VD+ +G Y C +N G S + + E Sbjct: 6292 KDDVELVSGPKCFI-GLEGSTSFLNLYSVDAS-KTGQYTCHVTNDVGSDSCTTMLLV-TE 6348 Query: 927 KVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 FVK L+ S + G + LEC+ S + W+ N+ E+ D + Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI 6408 Query: 985 XXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G C ++ ST ++VKE P F E + LE E+ Sbjct: 6409 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP-PVFSSFPPIVETLKNAEVSLECEL 6467 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 + + +VVW +D ++ K KY + ++I N D GEY C ++E + Sbjct: 6468 SGTPPFEVVWYKDKRQLRSSK-KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDT 6526 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE-IQFSNHIQ 1153 C V + E PP +++L + V G A + + + V+W K+ E I+ S +I+ Sbjct: 6527 CVCTVKLKE-PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIR 6585 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVP 1209 +T L+ + +AG+Y C++ G + A L V EP++ P + V Sbjct: 6586 ITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVG 6645 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 V E L V WYK ++ ++K K +L I D YT Sbjct: 6646 ETCTLECKVAGTPE-LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQ 6704 Query: 1270 LLD--AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VN 1324 + + KS+ V+V + PP + G+ L + W Sbjct: 6705 VQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEK 6764 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 +KI+ K+ + + +L + ++++D G Y N G + +T+ + PS Sbjct: 6765 TKIVSGAKY-QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFV 6823 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNL 1443 +P LE+ N+ + + + +E+ + ++ T + + N+ Sbjct: 6824 KEPEPLEVLPGK-NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNI 6882 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 + S + N + AS TT + +KE K L + + EP + I L Sbjct: 6883 DISQSGEYTCVVSN--NAGQASCTTRLF--VKE----PAAFLKRLSDHSVEPGKSIILES 6934 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 + G VTW +DG + T++ T E Y C N+ G Sbjct: 6935 TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRD 6994 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 +V + P E ++ VGD + + G P V WYK KL EY Sbjct: 6995 VCGALVSTLEPPYFVTELEPLEA--AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEY 7052 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 + + ++ + S +YT +A N+ GT+S + ++ ++ P +++I Sbjct: 7053 RTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIE 7112 Query: 1680 R 1680 + Sbjct: 7113 Q 7113 Score = 215 bits (525), Expect = 1e-53 Identities = 135/442 (30%), Positives = 209/442 (47%), Gaps = 13/442 (2%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISR 1680 K + R+K L ++ + A N AG S+ + +K P P G ++++ + Sbjct: 14865 KDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGK 14924 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 SV + W P DGG ++ Y IE + + W++VA+ + + + L E EY FR Sbjct: 14925 TSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQ-HLLPGLMEGQEYSFR 14983 Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A N G SE E S+P++ + L PS N + + W EK+GGSPI Sbjct: 14984 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKN-TADLKWTVPEKDGGSPI 15042 Query: 1800 IDYKVEIKQEGKK-WKXXXXXXXXX-ARIQKLSINTTYQFRIYARNEIGTSLPYTS-DDK 1856 +Y VE + +K W+ + L+ + Y FR+ A N IG S YT +D Sbjct: 15043 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQS-DYTEIEDS 15101 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 + T T P P V + T R V LKW P+++GG PI Y+IE K G W K Sbjct: 15102 VLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAG 15161 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 G + ++ E E+ F++ AEN GV P+E + + T P P L + Sbjct: 15162 KTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVT 15221 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD-LSENH 2035 G + +W PE +GG+P++GY++ + V WM V + LKF + + + + Sbjct: 15222 DAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDK 15281 Query: 2036 TYMIRIYARNEIGLSEPLESDE 2057 Y++R+ A N IG+SEP E E Sbjct: 15282 EYVLRVRAVNAIGVSEPSEISE 15303 Score = 215 bits (525), Expect = 1e-53 Identities = 213/871 (24%), Positives = 352/871 (40%), Gaps = 56/871 (6%) Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVE 1285 +W K I ++ + S L I+ T D EYT + T +KV V++ Sbjct: 21339 SWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLD 21398 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P E + +T + P +I+ + + T S D +S Sbjct: 21399 VPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH 21458 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMN--VTILDK---PSPPGKPNILEIDSSSINIC 1400 K+ + I+++ N+ G + + V ++D+ P PP KP + + ++ + Sbjct: 21459 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 21518 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W P + G S I Y VE +E + W+ ++K ++ + + L+ S+Y FR A N Sbjct: 21519 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 21578 Query: 1459 VDISDASETTEYYKVIKETKIQSP--------TVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 I SE ++ + P T +K +P+ D L V Sbjct: 21579 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 21638 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQ 1568 KV D +K T ++ A ND G E + + V I Sbjct: 21639 QKVG---DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 21695 Query: 1569 QKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 ++ + D + + + G + I+G P PEV W K+ L+N NI Sbjct: 21696 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENT 21753 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MR--EISRE 1681 E +++ I E R + K+ + N AG S V ++V D P GPV+ +R +I+++ Sbjct: 21754 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTP----GPVLNLRPTDITKD 21809 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 SVT+ W PL DGG +T Y +EK E + A TY + L+E CEY FRV Sbjct: 21810 SVTLHWDLPLIDGGSRITNYIVEKREATRKSY-STATTKCHKCTYKVTGLSEGCEYFFRV 21868 Query: 1742 IAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 +A+N G E E+ EP+ A P I +V + W + +GGS I Sbjct: 21869 MAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD----ITKSTVSLAWPKPKHDGGSKIT 21924 Query: 1801 DYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 Y +E +++G +W ++ L+ Y F++ A N G S P S I Sbjct: 21925 GYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 21984 Query: 1860 GKTLTPPSQPRNFVVSESTSRSV-TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 +T+ P R +++ +K P P + + +K T Sbjct: 21985 EQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETT 22044 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 S + E ++ D + ++A N VG + ++ H +P PPT P++ V Sbjct: 22045 ATSTILNINECVRS-DSGPYPLTARNIVG----EVGDVITIQVH-DIPGPPTGPIKFDEV 22098 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 S+ V SW PE DGG P+ Y + +R T W+E+ + T + L+ Y Sbjct: 22099 SSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRT-TYKATRLTTGLEYQ 22157 Query: 2039 IRIYARNEIGLSEPLES-----DEPFKVIPG 2064 R+ A+N G+ + S + PFKV PG Sbjct: 22158 FRVKAQNRYGVGPGITSACIVANYPFKV-PG 22187 Score = 213 bits (521), Expect = 3e-53 Identities = 239/1100 (21%), Positives = 425/1100 (38%), Gaps = 56/1100 (5%) Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD--ILEGIPPTFSKKPKAQYVDEGSDILL 653 T +I + DH E A +++ P +K + V G Sbjct: 4343 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKF 4402 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 C + + P W G EI + S+ Y S L+I + G YT A Sbjct: 4403 TCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK----YISSLEILRTQVVDCGEYTCKAS 4458 Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 N G S L + E PP + KS+ G++ V G P W K+ Sbjct: 4459 NEYGSVSCTATLTVT--EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 4516 Query: 774 PVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + P SD + I L ++D GVY+ KA N G A + + + Sbjct: 4517 ALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII-------ID 4569 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P FI + + + L +V + ++TW ++ + + P + F+ + L Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 4629 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 I + DSG Y C ASN AG SS A VT+ E +FVK + SY G++ L C+ Sbjct: 4630 IPLAKLK-DSGTYVCTASNEAGSSSCSATVTVR-EPPSFVKKVDPSYLMLPGESARLHCK 4687 Query: 952 T--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKD---QE 1005 S + W+ N KE+S + + D G C V D Sbjct: 4688 LKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDS 4747 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYD 1064 ST +V+KE P FI+ L+ ++ A+L+ E++ + ++ W +D + I+ K KY Sbjct: 4748 CSTEIVIKEP-PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-KYR 4805 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVT-VVELPPEIITRLQNQKVNKG 1121 + + L I + + D GEY C++ +E C T +++ PP + ++ + G Sbjct: 4806 LFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGG 4865 Query: 1122 NKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 T + + + + V W K I+ I+++ L I D + G+Y+C Sbjct: 4866 QTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLA 4925 Query: 1179 --EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235 E G+ L V+EP+ + E I V A A L + L WYK Sbjct: 4926 ENEAGSQTSVGELIVKEPA--KIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4983 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295 + ++K+ + L D +YT + + ++ + I + Sbjct: 4984 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFT 5043 Query: 1296 EYRIKRGSDV--TLLVDYQ-AFPQP-NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + S V T +D + A P W + K I + + +ASL I +V+ Sbjct: 5044 KPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVD 5103 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 DAG + R N+ G D + + + PS KP ++ S + + T Sbjct: 5104 MNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLT 5163 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 I ++ + + K ++ + +KT+ S + N + S Sbjct: 5164 IRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL--- 5220 Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----A 1527 +KE + VEK + + + +L C G P K+TW+ + +++K + + Sbjct: 5221 -FVKE---PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMS 5276 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 E+ Y C A N+ G S +V +++ P T + I+ + Sbjct: 5277 FVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY- 5335 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + ++ A + G PP E+ W+K+ L + ++Y ++ ++I + + + +Y Sbjct: 5336 -DVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRV 5394 Query: 1648 SNTAGTSSVEVTLKVYDKPS 1667 +N G+S + + + PS Sbjct: 5395 TNEVGSSICSARVTLREPPS 5414 Score = 213 bits (521), Expect = 3e-53 Identities = 206/899 (22%), Positives = 374/899 (41%), Gaps = 44/899 (4%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTL 1244 T I + P I+ L E + A T L I + + WYK ++ + Sbjct: 27789 TCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV 27848 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 + +++I+ + Y L +A ++ ++V++++ P E++ Sbjct: 27849 ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGP-PGGPIEFKTVTA 27907 Query: 1303 SDVTLLVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 +TLL A +IV + + + S + +T K+ + I+++ Sbjct: 27908 EKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRV 27967 Query: 1361 RLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 R N G + + +++ K P PPG P + +I +S+ + W P G S I Y Sbjct: 27968 RAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGY 28027 Query: 1416 VVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +E ++ + W V + I T+ + L NS Y++R AVN SE +E+YK Sbjct: 28028 FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKA 28087 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLK--TAKATY 1529 P + + + T ++ G V R G++ + T Sbjct: 28088 ADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKG 28147 Query: 1530 ENRXXXXXXXXXXXXXXXY-KCIAFNDHGEVE-TSCVVGIQQKPVITISNEDIKQK---- 1583 E R Y + A N G+ E +Q K ++ D+ Sbjct: 28148 EVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTS 28207 Query: 1584 --HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 K G++ V +G PPP V W K+ L +D Y+I + +S++ I ++ R+ + Sbjct: 28208 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 28267 Query: 1642 KYTIEASNTAG-TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 KY + N G S V++KV D P+ + + ++ +SR +VT+ W PPL DGG + Sbjct: 28268 KYILTIENGVGEPKSSTVSVKVLDTPAACQ-KLQVKHVSRGTVTLLWDPPLIDGGSPIIN 28326 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759 Y IEK + W V ++ + L+E + FRV+A+N +G E E +EP+ Sbjct: 28327 YVIEKRDATKRTW-SVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPV- 28384 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXX 1818 A +VP+ SV ++W + +GGS I +Y VE K +G++ W Sbjct: 28385 --KAAEVPAPIRDLSMKDS-TKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI 28441 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + +L + +FR++A+NE G S P T +TP + ++ T Sbjct: 28442 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 28501 Query: 1879 SR-SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 R + P P +++ + +K + + + I+N K++ Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGK 28560 Query: 1938 FRISAENTV-GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996 + + +N V +++P ++ PS P P+ + ++ V+ SW PE +GG Sbjct: 28561 YTVILDNAVCRIAVPITVITL------GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGG 28614 Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + Y+I R+ ++T W V V F + +L ++ Y R+ A N G+S+PL S Sbjct: 28615 EITCYSIEKRETSQTNWKMVCS-SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVS 28672 Score = 213 bits (520), Expect = 4e-53 Identities = 228/896 (25%), Positives = 367/896 (40%), Gaps = 72/896 (8%) Query: 1204 EFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 + + + A +D L + + + W K ++ EK +L K+ T +I+ C D Sbjct: 29982 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSD 30041 Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-- 1320 +YT + +A T + V V K++D S VT A+ P ++ Sbjct: 30042 SGKYTLTVKNASGTKAVSVMV-----KVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGG 30096 Query: 1321 -----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMN 1374 +IV + + + + S + ++ + I+++R N G VE Sbjct: 30097 AEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESE 30156 Query: 1375 VTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + PSPPG P + I I W +PE+ G + I Y+V+ +E + W V Sbjct: 30157 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 30216 Query: 1431 KN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP----- 1482 + T+ + +L Y+FR AVN S+ SE + + + + P Sbjct: 30217 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPR 30276 Query: 1483 ---TVEKPLKNITTEPNEDIELTCIFGGV--PQPKVT--WYRDGKKLKTAKATYENRXXX 1535 T + + T+P D T I G V Q K T WYR AT N Sbjct: 30277 VVDTTKHSISLAWTKPMYDGG-TDIVGYVLEMQEKDTDQWYR-----VHTNATIRN-TEF 30329 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVITISN----EDIKQKHKV--GD 1588 ++ A N G E S + I+ I I + +D+K+ + G Sbjct: 30330 TVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGA 30389 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 + + G PPP + W K G L + I T E S++ + ++ R + KYTIEA Sbjct: 30390 SLRLMVSVSGRPPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAE 30447 Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 N +G S V +KVYD P P V ++E+SR+SVTI W+ P DGG + Y +EK E Sbjct: 30448 NQSGKKSATVLVKVYDTPG-PCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREA 30506 Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768 R K Y I L E Y FRV+ +N G E E+ V+ + +VP Sbjct: 30507 AM-RAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVS--EVP- 30562 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ 1827 + +V + W +GGS + Y +E + G ++W Sbjct: 30563 LVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHT 30622 Query: 1828 KLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGK-----TLTPPSQPRNFVVSESTSR 1880 S+N Y FRI A+NE G S P + +T+ T+ + P+ + R Sbjct: 30623 VTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQK-TIHVPAGR 30681 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 V L P + P ++ ++ +S V V + I +D + + Sbjct: 30682 PVEL--VIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGEYTL 30738 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +N G + T + + L+K P PPT P++I + + + SW PE DGGAPL G Sbjct: 30739 ELKNVTGTTSET-IKVIILDK----PGPPTGPIKIDEIDATSITISWEPPELDGGAPLSG 30793 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 Y + RD + W+ V + V F L+E + Y+ R+ A N G+ L+S+ Sbjct: 30794 YVVEQRDAHRPGWLPVSE-SVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSE 30848 Score = 208 bits (508), Expect = 1e-51 Identities = 225/926 (24%), Positives = 383/926 (41%), Gaps = 55/926 (5%) Query: 1161 QKLKIYDCDLDDAG--EYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 Q+ KI C L+ G E + G K L E P ++ L + I+V A A + + Sbjct: 24916 QEYKIRVCALNKVGLGEATSVPGTVKPEDKL--EAPELDLDSELRKGIVVRAGGSARIHI 24973 Query: 1219 EIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 T ++TW +++ E T+K + V L I C +D +Y L ++ + Sbjct: 24974 PFKGRPTPEITWSREEG--EFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSK 25031 Query: 1278 K--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 + V+V++ P + +K + + ++ P + V + +I K + T+ Sbjct: 25032 SAFVTVKVLDTPGP----PQNLAVKEVRKDSAFLVWEP-PIIDGGAKVKNYVIDKRESTR 25086 Query: 1336 PSIDSKSA--SLTIKKVEN-TDAGIYKLRL--ENNCG-HADVEM--NVTILDKPSPPGKP 1387 + + S+ S T KVEN T+ IY R+ EN G VE V + PSPPGK Sbjct: 25087 KAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKV 25146 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 + ++ +S ++ W++PE+ G S ++ YVVE Q T +W V + L + Sbjct: 25147 TLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQ 25206 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 Y+FR A NE SD + K+ IQ P+++ P + + ED+++ G Sbjct: 25207 EYQFRVKAYNEKGKSD-PRVLGVPVIAKDLTIQ-PSLKLPFNTYSIQAGEDLKIEIPVIG 25264 Query: 1508 VPQPKVTWYRDGKKLK-TAKATYENRXXXX---XXXXXXXXXXXYKCIAFNDHGEVETSC 1563 P+P ++W +DG+ LK T + E Y A N G + Sbjct: 25265 RPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENL 25324 Query: 1564 VVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 V + +K PV + +++ V W A G I K + Sbjct: 25325 SVIVLEKPGPPVGPVRFDEVSADFVV-ISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVS 25383 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMR 1676 T T I+I +LK ++ I A N G S S V ++ K P G + Sbjct: 25384 ATVARTT--IKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVT 25441 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 IS++ + ++W P++DGG ++ Y +E+ E ++ W+K+ + L+E E Sbjct: 25442 SISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLE 25501 Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y F+V A+N VG + + SE V + D P I +V + W +G Sbjct: 25502 YEFKVSAENIVGIGKPSKVSECFVARDPCDPPG----RPEAIVITRNNVTLKWKKPAYDG 25557 Query: 1796 GSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPY 1851 GS I Y VE K +G+ K + L + Y+FR+ ARN G S P Sbjct: 25558 GSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS 25617 Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 S IT + P+ + + + G PI + + + + Sbjct: 25618 DSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEE 25677 Query: 1912 WTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969 + + ++ + +++ D + + N G T+S + + K P PP Sbjct: 25678 TAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG----TKSIPITV-KVLDRPGPP 25732 Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029 PL++ V + +W P DGGA + Y I R+ ++ W +V +V L + + Sbjct: 25733 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQV-STEVQALNYKVT 25791 Query: 2030 DLSENHTYMIRIYARNEIGLSEPLES 2055 L + Y+ R+ A N+ G+ EPLES Sbjct: 25792 KLLPGNEYIFRVMAVNKYGIGEPLES 25817 Score = 208 bits (507), Expect = 2e-51 Identities = 223/960 (23%), Positives = 396/960 (41%), Gaps = 70/960 (7%) Query: 750 ESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + VIL ++ P + W K+ K P K K+DG + ILK D G YT Sbjct: 12960 DEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRML-ILKKALKSDIGQYTCD 13017 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 G +TS + +E+ + P + V E T + ++ + + + W Sbjct: 13018 C----GTDKTSGKLDIEDREIKLVRP------LHSVEVMETETARFETEISEDDIHA-NW 13066 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 E + + +G+ LV+ N + +G A+N KSS RV V Sbjct: 13067 KLKGEALLQTPDCEIKEEGKIHSLVLHNCRLD-QTGGVDFQAANV--KSSAHLRVKPRV- 13122 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 + ++ L K G+T +C+ S+ + +WY K++ D EG+ Sbjct: 13123 -IGLLRPL-KDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLT 13180 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G ++ KD +T L VKE EF + L+D V+E A+LE E++ E A Sbjct: 13181 LRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENA 13240 Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W ++G EI+K KK Y+ G +RKL I + + D Y+C +D + + VV Sbjct: 13241 KVKWFKNGTEILKSKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVP 13298 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 E + L + +V + A FE EL++ +A V+WFKDG+EI+ + G + L Sbjct: 13299 PHVEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV 13358 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I C LDD EYSCEV ++ + +LTV E FT L I V L E+ Sbjct: 13359 INKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLAN-IEVSETDTIKLVCEVSKPG 13417 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 +V WYK I +T ++ ++++ +KR L+I+ +D Y C L S T KV+V Sbjct: 13418 AEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL--PSSRTDGKVKVH 13475 Query: 1285 EFPPKIVDYEREYRIKRG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 E + + + I G ++ + ++FP +W + K ++ D K Sbjct: 13476 ELAAEFISKPQNLEILEGEKAEFVCSISKESFPV---QWKRDDKTLESGDKYDVIADGKK 13532 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINIC 1400 L +K D G Y + + G A ++T+++K P K ++ + C Sbjct: 13533 RVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNC 13588 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 NT + ++ E D++++I ++ I++ + + N Sbjct: 13589 ---EVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 13645 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + S +++E ++ + +PLK+I T + + C + + W ++G+ Sbjct: 13646 ENVKSAAN---LIVEEEDLR---IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGE 13698 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNE 1578 ++ ++NR K F D GE V + + +I E Sbjct: 13699 EV-----PFDNR--VSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTE 13751 Query: 1579 DIKQKHKVGDEWLVTAVIE---GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 ++ AV V WY+NG +++ K+Y + IK+ Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDC 13811 Query: 1636 KRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSK-PEGP----VIMREISRESVTIEW 1687 + +Y + + + E+ +++ P E P V + E++++ V ++W Sbjct: 13812 RLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQW 13871 Score = 205 bits (501), Expect = 9e-51 Identities = 229/937 (24%), Positives = 390/937 (41%), Gaps = 70/937 (7%) Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 + ++ K++IY + + GE + G K + E ++ LR + + + A L Sbjct: 22750 ENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLR--KVVTIRACCTLRL 22807 Query: 1217 TVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 V I +V W + E +K ++ S LI+ D +Y + ++ Sbjct: 22808 FVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG 22865 Query: 1276 TTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + + V V++ P D + + K + VTL D P + + + I++K + Sbjct: 22866 SKSAFVNVRVLDTPGPPQDLKVKEVTK--TSVTLTWDP---PLLDGGSKIKNYIVEKRES 22920 Query: 1334 TKPSIDSKSASL--TIKKVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSPPG 1385 T+ + + + + T KV+ G +++ EN G A+ +V ++P PPG Sbjct: 22921 TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG 22980 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 K ++++ +S+++ W++PE+ G S I+ Y+VE Q + +W + + T+ +I L Sbjct: 22981 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQ 23040 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 Y FR A NE ISD + + VI + + P + T ED+++ F Sbjct: 23041 GEEYSFRVSAQNEKGISDPRQLS--VPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPF 23098 Query: 1506 GGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P P VTW++D LK A++T EN Y N GE Sbjct: 23099 IGRPTPAVTWHKDNVPLKQTTRVNAEST-ENNSLLTIKDACREDVGHYVVKLTNSAGEAI 23157 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN----D 1616 + V + KP +K DE ++ PP+ Y G+ + N Sbjct: 23158 ETLNVIVLDKP--GPPTGPVKM-----DEVTADSITLSWGPPK---YDGGSSINNYIVEK 23207 Query: 1617 KEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYD-KP 1666 ++ + TT + S I+ LK ++ I A N G S+ E T+ Y K Sbjct: 23208 RDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV 23267 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 P G ++ SR+S+ ++W P+ DGG + Y +E+ E ++ W+K+ + Sbjct: 23268 PGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKF 23327 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 L E EY FRV A+N VG + + SE V + D P + SV Sbjct: 23328 KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPG----RPEAIIVTRNSVT 23383 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXX-XXXXXXXARIQKLSINTTYQFRIYAR 1842 + W +GGS I Y VE K+ EG+ K + L + Y+FR+ AR Sbjct: 23384 LQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIAR 23443 Query: 1843 NEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N G S P S IT + PP + ++ + G PI I Sbjct: 23444 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-I 23502 Query: 1902 IEFKTVKGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 K + S T + + + +++ D + + A+N G T + V L Sbjct: 23503 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV-L 23561 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 ++ P PP P+ I V + +W P DGG+ ++ Y + R+ ++ +W V Sbjct: 23562 DR----PGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV-DA 23616 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 +V TL + L E + Y RI A N+ G+ EPLES+ Sbjct: 23617 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE 23653 Score = 205 bits (500), Expect = 1e-50 Identities = 242/1076 (22%), Positives = 420/1076 (39%), Gaps = 69/1076 (6%) Query: 633 PPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP--DENISVAIESDMH 689 PP F KK +A + V G LEC++ PE + W F+ E +P D+ I+S Sbjct: 6349 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW-FRNEHELPASDKYRMTFIDS--- 6404 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIEPLKSMIVR 747 +V+++ N+ G + A N G S +++K P ++E LK+ Sbjct: 6405 --VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNA--- 6459 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804 V L ++ G P + W K+ + + K S SI IL D G Y Sbjct: 6460 ---EVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVD-TSDIGEYH 6515 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 KA+N G + V TV+ EPP F+++ +TV +L A + + Sbjct: 6516 CKAQNEVG--SDTCVCTVKLK-----EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFV 6568 Query: 865 TWYRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + E +I SE I F EN+ + ++G Y C N G + A + + Sbjct: 6569 QWLKEKEEVIRESENIRITFV-ENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV 6627 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRX 981 +E V+ T G+T LEC+ + T +S +WY + K ++ + + Sbjct: 6628 -LEPAVIVEKAGPMTVTV-GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI 6685 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAI 1035 D G V++ ++S VV + P F R+L++ I Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCI 6745 Query: 1036 LEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD- 1093 LE ++ S V W + I KY ++ L + + D G Y+C+ + Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGA-KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 6804 Query: 1094 ---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149 + C A +TV E PP + + +V G TF + V WF+ E+ Sbjct: 6805 AGSDECRAVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG 6863 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEF 1205 + + + +L++++ D+ +GEY+C V N+ CT L V+EP+ F RL + Sbjct: 6864 DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA-FLKRLSDH 6922 Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 + P + + + VTW K I +EK +++ K L I T+ D + Sbjct: 6923 SVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQ 6982 Query: 1266 YTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y+C + + + V +E PP V G V+L P+ W Sbjct: 6983 YSCEIENEAGRDVCGALVSTLE-PPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYK 7041 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 ++ + + A+L KV D+G Y + EN+ G A + I ++ P Sbjct: 7042 GDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP 7101 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE---IDTTEWISVKNITKTQTSI 1440 P L+ ++ + S I V Y++ + E + + T + Sbjct: 7102 PSFARQLKDIEQTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDDENLQTSFVDNVAT-L 7159 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 + L+T+ S+ + + AS + +E K +SP + +I E + Sbjct: 7160 KILQTDLSHSGQYSCSASNPLGTASSSARL--TAREPK-KSPFFDIKPVSIDVIAGESAD 7216 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 C G ++TW +D K+++ N Y C A ND Sbjct: 7217 FECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDV 7276 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G+ S + +++ P + + + K G+ + I G P +V W++N ++L Sbjct: 7277 GKDMCSAQLSVKEPPKF-VKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 7335 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 +YN++ +++ I E S Y EA N G +S L V P + P Sbjct: 7336 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKP 7391 Score = 205 bits (500), Expect = 1e-50 Identities = 228/1047 (21%), Positives = 410/1047 (39%), Gaps = 71/1047 (6%) Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 +E+ P + V + ++ + A V W KDG ++ + + ++ Sbjct: 26318 IEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT 26377 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCT-----AILTVEEPSINFTLRLPEFILVPANTDAYL 1216 L I + +D G Y V NS + I+ ++ P +R+ E + + T ++ Sbjct: 26378 SLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDE-VSCDSITISWN 26436 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI--IRKCTEDDQCEYTCV--LLD 1272 E D ++ Y + + + ++S RT I +R T + C Sbjct: 26437 PPEY-DGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYG 26495 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 S ++ V E+P ++ + T+LV +Q ++ + + K Sbjct: 26496 KSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL--EYK 26553 Query: 1333 HTKPSIDSKSASLTIK----KVENTDAGI---YKLRLENNCGHADVEMN---VTILDKPS 1382 + SK+ + I KV D G+ Y++ EN G + V D Sbjct: 26554 ERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 26613 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSI 1440 PPG+P + I S+++ W +P G + I Y+VE +E+ W+ NI +T + Sbjct: 26614 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 26673 Query: 1441 QNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTEPN 1496 L + Y FR +A N D +S+ SE+T +I + ++ P V +K I + Sbjct: 26674 TELTEDQRYEFRVFARNAADSVSEPSESTG--PIIVKDDVEPPRVMMDVKFRDVIVVKAG 26731 Query: 1497 EDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 E +++ G P P ++W +DG ++ +T + +N Y Sbjct: 26732 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 26791 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIK--QKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 N G + + KP +I K W G ++ +Y Sbjct: 26792 KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGA---DIDYYIVE 26848 Query: 1611 NKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSV--EVTLKVYDKPS 1667 + + + I E + + ++ +L + + + + N G V +K D + Sbjct: 26849 KRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFT 26908 Query: 1668 KPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P P + +++ES+T+ W P DGG E++ Y IE+ E ++ RW++V + V Sbjct: 26909 VPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNK--KPVYD 26966 Query: 1726 YCIQK--LNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNE 1782 ++ L E CEY +RV A+N G S E+ P++ + + +PS Sbjct: 26967 LRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDS-GKT 27025 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIY 1840 ++ I W +GG+PI Y VE K+ + WK I L+ Y FR+ Sbjct: 27026 TITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVK 27085 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 + N++G S P S D + P + + ++ +T G P+ N Sbjct: 27086 SVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPN- 27144 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 ++ K V S IEN D + ++ +N + + T + Sbjct: 27145 VLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT-----LVV 27199 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 K P PPT + ++ V + SW PE DGGAP+ Y+I R+ +K W+ V + Sbjct: 27200 KVLDTPGPPTN-ITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTN-N 27257 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVX 2080 N L + + +L E Y R+ NE G+ P E+ E K+ E+P ++ Sbjct: 27258 CNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI--------TEKPSPPEKLG 27309 Query: 2081 XXXXXXXXXXXXWLR-EHNMDADIRSY 2106 WL+ EH+ + I Y Sbjct: 27310 VTSISKDSVSLTWLKPEHDGGSRIVHY 27336 Score = 202 bits (494), Expect = 6e-50 Identities = 174/670 (25%), Positives = 270/670 (40%), Gaps = 36/670 (5%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W + K + ++ +KS L IK D G Y + N+CG Sbjct: 16059 PVPTKVWTKEEGELDKDRVVIDNVGTKS-ELIIKDALRKDHGRYVITATNSCGSKFAAAR 16117 Query: 1375 VTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 V + D P P KP + +N W +PE+ G S I +++E ++ W Sbjct: 16118 VEVFDVPGPVLDLKPVVTNRKMCLLN--WSDPEDDGGSEITGFIIERKDAKMHTWRQPIE 16175 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 +++ I L Y+FR A N+ E V SP + Sbjct: 16176 TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTK 16235 Query: 1493 TEPNEDIELTCIFGGVP-QPKVTWYR--DGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 + D + GG P Q + R D + ++ Sbjct: 16236 STITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFR 16295 Query: 1550 CIAFNDHGEVETSCVVGI-----QQKPVITI--SNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 A N+ GE E S + + + P I + S K K G+ + A + G+P P Sbjct: 16296 VKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMP 16355 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGTSSV 1656 ++ W KN +E + TKE+ S + I + R YT+ ASN G+ Sbjct: 16356 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 16415 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WI 1714 V ++VYD+PS P + + +I ES + W PLD+GG E+T Y I+K + + W Sbjct: 16416 NVHVEVYDRPSPPRN-LAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWE 16474 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 +V + + + Y I KL N +Y FRV A N G S+ +S+ +VI+ +P Sbjct: 16475 EVTNTAVE-KRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPK 16533 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT 1833 S+ ++W P NGGSPI Y +E ++EG W ++ + N Sbjct: 16534 VLARTKG-SMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNV 16592 Query: 1834 T-------YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 YQFR A N G P D G + PP P V + T S++L W Sbjct: 16593 PRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGW 16652 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAEN 1944 P +GGSPI YI+E + W ++ + E + N+KE + FR+ A N Sbjct: 16653 KPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVN 16712 Query: 1945 TVGVSLPTES 1954 G S P+++ Sbjct: 16713 EAGESEPSDT 16722 Score = 202 bits (494), Expect = 6e-50 Identities = 217/903 (24%), Positives = 372/903 (41%), Gaps = 67/903 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRT 1252 PS+ ++L E ++V A T I + W S I+ E +T+ +D Sbjct: 18435 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 18494 Query: 1253 LIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L I+ C D EY + +A T + + V++ P I + + + Sbjct: 18495 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTG---PINILDVTPEHMTIS 18551 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAG---IYKLRLENN 1365 +Q ++N I++K K + + S +S T K+ + G ++++R EN Sbjct: 18552 WQPPKDDGGSPVINY-IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 18610 Query: 1366 CGHAD-VEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 G ++ T+ PSPPGKP + +I ++ + W P++ G S I Y +E + Sbjct: 18611 IGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERR 18670 Query: 1421 EIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 E+ T +W+ V I + + L ++Y FR +A N +S S +++ K + K Sbjct: 18671 EV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIK 18729 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538 P + LK+ + E D+ T P + + + +K TA+ N+ Sbjct: 18730 PPGPPINPKLKDKSRE-TADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 18788 Query: 1539 XXXXX------XXXXYKCIAFNDHGE------VETSCVVGIQQKPVIT--ISNEDIKQKH 1584 ++ A N GE E+ I P + ++ D+ Sbjct: 18789 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITV- 18847 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 +VG + A ++G P P++ W K G L +K ++ ++IKE R+ KY Sbjct: 18848 RVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYI 18907 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I A N++G + + V D+P P + + +++E+ TI W+ PLD+GG E+T + +E Sbjct: 18908 ISAKNSSGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVE 18966 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQ-KLNENCEYMFRVIAQNPVGFSEALESE-PIVIKT 1762 +P+ W VA DV I+ L N EY FRV A+N VG +E++ PI+ Sbjct: 18967 YRKPNQKGWSIVAS---DVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAIN 19023 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821 +D P VY+ W + +GGSP + Y VE + +G W+ Sbjct: 19024 PIDRPGEPENLHIADK-GKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSI 19082 Query: 1822 XXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 + + N Y+FR+ +NE G S + +++ + + L P V+ S Sbjct: 19083 KETHYMVDRCVENQIYEFRVQTKNEGGES-DWVKTEEVVVKEDLQKP------VLDLKLS 19135 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-------VTVGGSVHEHCIENIKE 1932 +T+K + E K K T + + + + K Sbjct: 19136 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 19195 Query: 1933 KDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992 D + ++A NT G + + +V L+K P L+I V S+ W PE Sbjct: 19196 SDGGKYVVTATNTAGSFVAYATVNV-LDKPG-----PVRNLKIVDVSSDRCTVCWDPPED 19249 Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 DGG + Y I + TK M V T + L E + Y+ R+ A N+IG P Sbjct: 19250 DGGCEIQNY-ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPP 19308 Query: 2053 LES 2055 ES Sbjct: 19309 TES 19311 Score = 202 bits (493), Expect = 8e-50 Identities = 182/753 (24%), Positives = 322/753 (42%), Gaps = 44/753 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V E + EC + P+ WL +EI D+ + + H V+K + Sbjct: 12778 VFEKDEAKFECEVSREPKT-FRWLKGTQEITGDDRFELIKDGTKHSM--VIKSAAFE--D 12832 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 E Y A ++ L I+ I+ + + PLK + ++ ES + + ++ + Sbjct: 12833 EAKYMFEAEDKHTSGKL-IIEGIRL------KFLTPLKDVTAKEKESAVFTVEL-SHDNI 12884 Query: 765 TITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W KN++ + +++ + +G THSIT K + D ++A + A +T Sbjct: 12885 RVKWFKNDQRLHTTRSVSMQDEGKTHSITF-KDLSIDDTSQIRVEAMGMS----SEAKLT 12939 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V E P F + Q+ T EK + L +++ P + W+++ + I PS+ Sbjct: 12940 VLEGD------PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVI 12992 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 DG+ L++ + D G Y C G ++ I+ ++ V+ L S E Sbjct: 12993 KADGKKRMLILKKA-LKSDIGQYTC----DCGTDKTSGKLDIEDREIKLVRPLH-SVEVM 13046 Query: 942 EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 E +T E + S + W + + EI +EG+ G + Sbjct: 13047 ETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQ 13106 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 + ++S L VK + +R L+D V + A + E++ E V W G+ ++P Sbjct: 13107 AANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPS- 13165 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 +K G + L +R+ + D GE +D A + V E P E L++Q V + Sbjct: 13166 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 13225 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 G A E E+++ +A V+WFK+G+EI S ++ DG+ +KL I+DC +D Y+C+ Sbjct: 13226 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 13285 Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 + K + L V P + F L + + V A E+ E V W+K + I+ + Sbjct: 13286 KDFKTSCNLNVVPPHVEFLRPLTD-LQVREKEMARFECELSRENAKVKWFKDGAEIKKGK 13344 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFPPKIVDYEREYR 1298 K+ +IS R L+I KC DD+ EY+C + A+++ L V E F + + E Sbjct: 13345 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSE- 13403 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +D LV + P W + I + + + + L I+ DAG Y Sbjct: 13404 ----TDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNY 13459 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 RL ++ V+++ + S P ILE Sbjct: 13460 NCRLPSSRTDGKVKVHELAAEFISKPQNLEILE 13492 Score = 202 bits (493), Expect = 8e-50 Identities = 187/693 (26%), Positives = 290/693 (41%), Gaps = 34/693 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 P P P + + S+ + W+ P + G S I+ YV+E ++ + W I + + Sbjct: 23664 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 23723 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + L N Y FR A N +S+ S + Y K P + +IT Sbjct: 23724 RVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFL 23783 Query: 1499 IELTCIF-GGVP-QPKVTWYRD---GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 I+ GG Q + D G+ T N+ ++ A Sbjct: 23784 SWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAI 23843 Query: 1554 NDHGEVETSCVVG---IQQK---PVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIW 1606 N G E + V G +++K P I + E K + + G + I+G P PEV W Sbjct: 23844 NKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW 23903 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K ++ + ++T+ TS++ + + R S KYT+ N++GT S VT++V D P Sbjct: 23904 GKVDGEIRDAAIIDVTSSF-TSLV-LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23961 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 S P + + EI+++SV+I W+PPL DGG ++ Y +EK E + V + ++ Sbjct: 23962 SPPVN-LKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVV-TNCHKNSW 24019 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 I +L E C Y FRV A+N G A ++PI + P + SV Sbjct: 24020 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPG----KITVDDVTRNSVS 24075 Query: 1786 ITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 ++W E +GGS II Y VE++ + +KW A I L+ Y FR+ A NE Sbjct: 24076 LSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNE 24135 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 G S P + I + K L + S S LK P S P + + Sbjct: 24136 KGRSDPRSLAVPI-VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG 24194 Query: 1905 KTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 + K T+I VT + I+ + D + I+ N VG + V L+K Sbjct: 24195 LPL--KQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVG-QKTASIEIVTLDK-- 24249 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 P PP P++ V + + SW P + GG + Y + RD T T+W +V V Sbjct: 24250 --PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVW-DVVSATVAR 24306 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + L Y RI+A N G S LESD Sbjct: 24307 TTLKVTKLKTGTEYQFRIFAENRYGQSFALESD 24339 Score = 200 bits (488), Expect = 3e-49 Identities = 172/697 (24%), Positives = 288/697 (41%), Gaps = 38/697 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK---TQ 1437 P PP P++ + S ++ W +P G I YVVE+Q++ WI T TQ Sbjct: 21600 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 21659 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 + +L+T Y FR A+N+ + + + + V +E + + + Sbjct: 21660 FVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGL 21719 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDH 1556 I + G P P+VTW +D LK +A EN K + ++ Sbjct: 21720 SIRIFVPIKGRPAPEVTWTKDNINLKN-RANIENTESFTLLIIPECNRYDTGKFVMTIEN 21778 Query: 1557 GEVETSCVVGIQ----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 + S V ++ PV+ + DI K V W + + G + Y + Sbjct: 21779 PAGKKSGFVNVRVLDTPGPVLNLRPTDIT-KDSVTLHWDLPLIDGG---SRITNYIVEKR 21834 Query: 1613 LENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVT--LKVYDKPSK 1668 K Y+ TTK ++ L + + A N G E T +K + PS Sbjct: 21835 EATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSP 21894 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P+ IM +I++ +V++ W P DGG ++T Y IE +++W + V + +E + Sbjct: 21895 PDSLNIM-DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV-KGLECV-V 21951 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI-----DNES 1783 + L E EY F+V+A N G S ES P+++K +P + DN Sbjct: 21952 RNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIK 22011 Query: 1784 VYITWFPSEKNGGSPIIDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 V I K P + +K +I ++ ++ I + + + + + A Sbjct: 22012 VEIPVLGRPK----PTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTA 22067 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 RN +G + I + PP+ P F E +S VT W PE++GG PI+NY+ Sbjct: 22068 RNIVGEVGDVIT---IQVHDIPGPPTGPIKF--DEVSSDFVTFSWDPPENDGGVPISNYV 22122 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +E + +W ++ T + + E FR+ A+N GV S + Sbjct: 22123 VEMRQTDSTTWVELATTVIRT-TYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANY 22181 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 VP PP P ++ V + + SW P DGG+P+LGY++ ++ +W V K V Sbjct: 22182 PFKVPGPPGTP-QVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV 22240 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 F L++ Y R+ A N G S+P + EP Sbjct: 22241 PGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEP 22277 Score = 199 bits (485), Expect = 8e-49 Identities = 194/869 (22%), Positives = 358/869 (41%), Gaps = 53/869 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVV 1284 VTW + + ++ T+ + +++I+ C Q Y+ + + K + V+V+ Sbjct: 17483 VTWNMNERTLP--QEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 17540 Query: 1285 EFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 + P P + +T P +++ + + T + Sbjct: 17541 DVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ 17600 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSI 1397 + T++ + A +++ EN+ G VE + ++ + P P + E+ +++ Sbjct: 17601 NATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTV 17660 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 + W+ P+ G S II YV+E + I T ++ V N + + +++ LK +Y +R A Sbjct: 17661 TLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSA 17720 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVT 1514 VN V S T+ + + ++ PT+ ++ +T E LT + G P+PKV+ Sbjct: 17721 VNIVGQGKPSFCTK--PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVS 17778 Query: 1515 WYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 W++D + +T T Y + N G + C V + + Sbjct: 17779 WFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDR 17838 Query: 1571 ---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 PV +S +++ + + V W G I K ++ D +T+ Sbjct: 17839 PGPPVGPVSFDEVTKDYMV-ISWKPPLDDGGSKITNYIIEK--KEVGKDVWMPVTSASAK 17895 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSS--VEVTLKVYDK---PSKPEGPVIMREISRES 1682 + ++ +L + I A N G S V ++K D+ P P+ P++ E++++S Sbjct: 17896 TTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIV-TEVTKDS 17954 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRV 1741 + W P DGG +T Y +EK E + RW +V D + + L E C+Y FRV Sbjct: 17955 ALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRV 18013 Query: 1742 IAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 A+N +G + + S+P+ K + PS N SV +TW P +GGS I+ Sbjct: 18014 SAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCN-SVDLTWQPPRHDGGSKIL 18072 Query: 1801 DYKVEIKQEG-KKWKXXXXX----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 Y VE ++ G ++W+ ++ L TY+FR+ A N G S P + Sbjct: 18073 GYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPE 18132 Query: 1856 KITIGKTLTPPS--QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + + L PP N + TL+ + P + E + K+ Sbjct: 18133 PVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI 18192 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973 + VG + I N +D I+ ++ EN G S + + L+K P PP L Sbjct: 18193 DVTPVGSKLE---IRNAAHEDGGIYSLTVENPAG-SKTVSVKVLVLDK----PGPP-RDL 18243 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033 E+ + + +W P DGG+ + Y + RDV W + F + L+E Sbjct: 18244 EVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNE 18302 Query: 2034 NHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 + Y+ R+ A N+ G +E+ +P K + Sbjct: 18303 GNQYLFRVAAENQYGRGPFVETPKPIKAL 18331 Score = 198 bits (483), Expect = 1e-48 Identities = 131/433 (30%), Positives = 196/433 (45%), Gaps = 19/433 (4%) Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN--GNKLENDKEYNITTKEK 1626 QKPV+ + + K GD + A + G P PEV W K+ L I T+ Sbjct: 19126 QKPVLDLKLSGVLTV-KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 19184 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 +S + + KRS KY + A+NTAG+ T+ V DKP I+ ++S + T+ Sbjct: 19185 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVC 19243 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W PP DDGG E+ Y +EK E W + T + +L E EY+FRV A+N Sbjct: 19244 WDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGT-TVTRLIEGNEYIFRVRAENK 19302 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 +G ES+P++ KT D P + E + + W P E +GG I Y +E Sbjct: 19303 IGTGPPTESKPVIAKTKYDKPGRPDPPEVTK-VSKEEMTVVWNPPEYDGGKSITGYFLEK 19361 Query: 1807 KQE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 K++ +W R +Q L + YQFR+ A NEIG P + + Sbjct: 19362 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 19421 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-----TVKGKSWTKIVTV 1918 PP P NF V ++T S+TL W +P +GG+PI Y++E + + W + Sbjct: 19422 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 19481 Query: 1919 GGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 V E + ++ E E FR+ A+N VG+ P E + K + PP L+ M Sbjct: 19482 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKE--ILEPPEIDLDASM 19539 Query: 1978 VGSNIVMTSWGTP 1990 +V+ G P Sbjct: 19540 --RKLVIVRAGCP 19550 Score = 198 bits (483), Expect = 1e-48 Identities = 168/659 (25%), Positives = 292/659 (44%), Gaps = 41/659 (6%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 ++W++ G E+ S +++ DG+ L + + +D G Y+C EVG + ++ L ++ Sbjct: 31491 IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 31550 Query: 1193 E-PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250 P + L E + L V + +TW+ + +++++E T+ + Sbjct: 31551 ATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHY 31610 Query: 1251 RTLIIRKCTEDDQC-EYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 L+++ +Y L + T L VE+ + P K + + S V Sbjct: 31611 THLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAV-- 31668 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENT--DAGIY-KLR 1361 + ++ WI N +++KC+ + + + S + S+T ++ N +AG Y ++ Sbjct: 31669 -ISWKPPADDGGSWITNY-VVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVS 31726 Query: 1362 LENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 +N G +D +E++ ++ +KP PGKP I + S + W P + G + I Y Sbjct: 31727 AQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNY 31786 Query: 1416 VVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +E +E +WISV + I +T S++NL Y FR N S+ SE +E Sbjct: 31787 YLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITP 31846 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 + IQ+P ++ L+N+ + L C G P+P V WYR GK++ Y + Sbjct: 31847 KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQE 31906 Query: 1534 XXXX------XXXXXXXXXXYKCIAFNDHGEVE--TSCVVGIQQKPVITISNEDIKQKHK 1585 Y+ A N G V S V + K + + E + H Sbjct: 31907 FKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHA 31966 Query: 1586 V-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKY 1643 + G+ + G P P + W K + ++N+ Y I T+ TS++ ++R + Y Sbjct: 31967 LRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFY 32026 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 + A N G V L V D P P G V + ++SR+SV + W P DGG ++T Y + Sbjct: 32027 VVCAKNRFGIDQKTVELDVADVPDPPRG-VKVSDVSRDSVNLTWTEPASDGGSKITNYIV 32085 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761 EK RW++V R+ Y + L Y FRVIA+N G S+ E SEP + K Sbjct: 32086 EKCATTAERWLRVGQA-RETR-YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITK 32142 Score = 196 bits (477), Expect = 7e-48 Identities = 175/699 (25%), Positives = 298/699 (42%), Gaps = 44/699 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437 P PP P + + SS+++ W +P G + + YVVE +E EW + + Q Sbjct: 25930 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 25989 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 ++ LK N+ Y FR A+N + + + T V+ + +I+ P +E K + Sbjct: 25990 FTVTKLKENTEYNFRICAINSEGVGEPA--TLPGSVVAQERIEPPEIELDADLRKVVVLR 26047 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCI 1551 + + L G P+P+V W + + + T +A E + Y Sbjct: 26048 ASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLT 26106 Query: 1552 AFNDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N+ G V + P + ++ ++K K V W +I+G ++ Y Sbjct: 26107 LENNSGSKTAFVNVRVLDSPSAPVNLTIREVK-KDSVTLSW-EPPLIDG--GAKITNYIV 26162 Query: 1610 GNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV-YDKP 1666 + K Y IT + RI+ L+ S + + ASN G E T V +P Sbjct: 26163 EKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEP 26222 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 P G V + +++R + TI+W+ P DGG ++T Y +E + +W V + +E Sbjct: 26223 PLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQV-KTLEA- 26280 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 I L EY+FRV A N G S+ + P++ + PS E + Sbjct: 26281 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNE 1844 I P + G P V +++G+ K ++ + LSI ++ + Sbjct: 26341 ID-VPFK---GRP--QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEA------SKED 26388 Query: 1845 IGTSLPYTSDD--KITIGKT---LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 +GT S+ IT+ T L P P + E + S+T+ W PE +GG I+N Sbjct: 26389 VGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISN 26448 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 YI+E K +W IV+ + I + E FR+ AEN G S +ES +V Sbjct: 26449 YIVEKKETTSTTW-HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 26507 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 E + P PP P + S +++T W P DGG+ ++GY++ ++ + +W + K+ Sbjct: 26508 EYPFSPPGPPGTPKVVHATKSTMLVT-WQVPVNDGGSRVIGYHLEYKERSSILWSKANKI 26566 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + + L E Y R+YA N G+ + +S EP Sbjct: 26567 LIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEP 26605 Score = 195 bits (475), Expect = 1e-47 Identities = 186/711 (26%), Positives = 309/711 (43%), Gaps = 65/711 (9%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQ 1437 P+PP P + + SS+++ W +P G S II Y+VE + D+ W+ +N+ KT+ Sbjct: 20516 PAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 20575 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPN 1496 + L ++ Y+FR YAVN++ SD S+ + + ++ L K + Sbjct: 20576 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 20635 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCI 1551 + L G P PK+TW + L+ K+T + Y Sbjct: 20636 VTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKST-DFDTFLRCENVNKYDAGKYILT 20694 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT---AVIEGIPPPEVIWYK 1608 N G+ E + VV + P + N +K+ K D VT +I+G P +I Y Sbjct: 20695 LENSCGKKEYTIVVKVLDTPGPPV-NVTVKEISK--DSAYVTWEPPIIDGGSP--IINYV 20749 Query: 1609 NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + K ++ T E KTS R+ L+ S + + A N G T K Sbjct: 20750 VQKRDAERKSWSTVTTECSKTS-FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAV-KA 20807 Query: 1667 SKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 S+ GPV+ +R +S+ S +I WK P DGG + Y ++ + N+W +V + Sbjct: 20808 SQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRVMK-SLSL 20865 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + Y + L E EY FRV A+N G E SE I + DV + +D + Sbjct: 20866 Q-YSAKDLTEGKEYTFRVSAENENG--EGTPSE-ITVVARDDVVAPD--------LDLKG 20913 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGK-----KWKXXXXXXXXXARI--QKLSINTTYQ 1836 + + +++N +++++I +GK WK R+ + ++NTT Sbjct: 20914 LPDLCYLAKENS-----NFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLI 20968 Query: 1837 FRIYARNEIGT------SLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEP 1889 +++ G ++ T + I+I K + P P + E T+ ++TLKW P Sbjct: 20969 VYDCQKSDAGKYTITLKNVAGTKEGTISI-KVVGKPGIPTGPIKFDEVTAEAMTLKWAPP 21027 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVG 1947 + +GGS ITNYI+E + W VT +V + + + E E FR+SAEN G Sbjct: 21028 KDDGGSEITNYILEKRDSVNNKW---VTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 21084 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 V +S+ + VP P P I V + V +W P+ GG+P+ GY++ ++ Sbjct: 21085 VGEGLKSEPIVARHPFDVPDAPPPP-NIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKE 21143 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 +W K + F + L+E Y R+ A N G+ +P EP Sbjct: 21144 RNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEP 21194 Score = 194 bits (474), Expect = 2e-47 Identities = 212/907 (23%), Positives = 361/907 (39%), Gaps = 56/907 (6%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249 +E P I+ L L + I + A L V I T +V W K I D + S Sbjct: 23864 LEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT 23923 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +L++ D +YT L ++ T + V V++ P V+ + K +T Sbjct: 23924 --SLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW 23981 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 +IV + + + + S I +++ + +++ EN G Sbjct: 23982 EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG 24041 Query: 1368 ---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 A + + + P PPGK + ++ +S+++ W +PE+ G S II Y+VE Q + Sbjct: 24042 IGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHS 24101 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 +W + Q I NL Y FR AVNE SD ++ + + P V Sbjct: 24102 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA--VPIVAKDLVIEPDV 24159 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544 + + + + +D+++ G P+P +TW +DG L K T Sbjct: 24160 KPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL---KQTTRINVTDSLDLTTLSI 24216 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQK----PVITISNED-IKQKHKVGDEWLVTAVIEGI 1599 +K +D G+ + + QK ++T+ D K K D + + Sbjct: 24217 KETHK----DDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWN 24272 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASNTAGT 1653 PP + N + ++ T + S +++ +LK ++ I A N G Sbjct: 24273 PPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQ 24332 Query: 1654 S-SVEVTLKVYDKPSK---PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 S ++E V P K P G IS++S+ I+W P+++GG + Y +E+ E + Sbjct: 24333 SFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 24392 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPS 1768 + W KV + Q L E EY FRV A+N VG +A + SE V + D P Sbjct: 24393 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 24452 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXA-R 1825 + + + W +GGS I Y VE + +G+ K Sbjct: 24453 ----TPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFT 24508 Query: 1826 IQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSV 1882 + L+ + Y+FR+ A+N G S P S IT + P S F + + Sbjct: 24509 VSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGE 24568 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 T + P ++ K ++ + +I +++ D + + A Sbjct: 24569 TFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKA-LLIVKDAIRIDGGQYILRA 24627 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 N G ++S V + K P PP P+++ V S +W P DGG+ + Y Sbjct: 24628 SNVAG----SKSFPVNV-KVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYV 24682 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES-----DE 2057 + R+ ++ W V +V T + L E + Y+ RI A N+ G+ EPLES Sbjct: 24683 VEKRETSRLAWTVVAS-EVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741 Query: 2058 PFKVIPG 2064 PF V+PG Sbjct: 24742 PF-VLPG 24747 Score = 192 bits (467), Expect = 1e-46 Identities = 176/700 (25%), Positives = 303/700 (43%), Gaps = 46/700 (6%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NIT 1434 +D P PP K I + SSI + W +P G S + YVVE ++ + EW +V + Sbjct: 28091 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 28150 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNI 1491 T+ + NLK +Y FR AVN + E E V + +++P ++ + ++ Sbjct: 28151 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNE--PVQAKDILEAPEIDLDVALRTSV 28208 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXX---XXXXXXXX 1547 + ED+++ F G P P VTW +D K L A+ + EN Sbjct: 28209 IAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGK 28268 Query: 1548 YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKH-KVGDEWLV--TAVIEGIPPPE 1603 Y N GE ++S V V + P + + ++ KH G L+ +I+G P Sbjct: 28269 YILTIENGVGEPKSSTVSVKVLDTPA---ACQKLQVKHVSRGTVTLLWDPPLIDGGSP-- 28323 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS-VEVT-- 1659 +I Y + + +++ + + +S ++ +L + + A N G E T Sbjct: 28324 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP 28383 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 +K + P+ P + M++ ++ SV + W P DGG +T+Y +E+ W A + Sbjct: 28384 VKAAEVPA-PIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAGI 28441 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 + E + +L E FRV A+N G S+ + PI +K + P + Sbjct: 28442 SKTCEIE-VSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQV 28500 Query: 1780 D---NESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARIQKLSINTT 1834 +V++ P K P I + + +E + + I+ Sbjct: 28501 TVRIGHNVHLE-LP-YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 28558 Query: 1835 YQFRIYARNEI-GTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESN 1892 ++ + N + ++P T IT+G PPS+P+ + E + SV L W PE N Sbjct: 28559 GKYTVILDNAVCRIAVPIT---VITLG----PPSKPKGPIRFDEIKADSVILSWDVPEDN 28611 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 GG IT Y IE + +W K+V + + N+ + E FR+ AEN GVS P Sbjct: 28612 GGGEITCYSIEKRETSQTNW-KMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPL 28670 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 S + + +P PP P+ I V S+ + +W P +DGG+ + G+++ ++ + Sbjct: 28671 VSSIIVAKHQFRIPGPPGKPV-IYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSIL 28729 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 W +V ++ ++ L E Y R+YA N GLS P Sbjct: 28730 WQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSP 28769 Score = 191 bits (466), Expect = 2e-46 Identities = 205/757 (27%), Positives = 301/757 (39%), Gaps = 73/757 (9%) Query: 1349 KVENTDAG-IYKLRL--ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 KV AG IY+ R+ EN G + V +D PP I +I +S+++ W Sbjct: 27657 KVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQ 27716 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEV- 1459 +P G S I Y+VE +++ W S N+T+TQ I L NS Y FR +A N V Sbjct: 27717 QPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVG 27776 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTEPNEDIELTCIFGGVPQPKVTWY 1516 IS+ SE I P ++ PL+ + ++L G P P + WY Sbjct: 27777 SISNPSEVVGPITCIDS--YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWY 27834 Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAF---NDHGEVETSCVVGIQQKP- 1571 +D K+L+T A EN C N G + V I KP Sbjct: 27835 KDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPG 27894 Query: 1572 -------VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 T++ E I + G + ++E V+W LE E Sbjct: 27895 PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLE---ECI 27951 Query: 1621 ITTKEKTSVIRIKE--LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 ITT T +I+ E + +KY I + SV V + P P P + + I Sbjct: 27952 ITT---TKIIKGNEYIFRVRAVNKYGI--GEPLESDSV-VAKNAFVTPGPPGIPEVTK-I 28004 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEY 1737 ++ S+T+ W P+ DGG +++ Y +EK + + W KV + RD + L EN +Y Sbjct: 28005 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQK-VTGLTENSDY 28063 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 +RV A N G + SEP A D P S+ + W +G Sbjct: 28064 QYRVCAVNAAG--QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDG 28121 Query: 1796 GSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPY 1851 GS + Y VEI+Q E ++W + L Y FR+ A N G P Sbjct: 28122 GSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 28181 Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKG 1909 ++ P Q ++ + + V L+ T + G + +I FK Sbjct: 28182 EMNE----------PVQAKDILEAPEIDLDVALR-TSVIAKAGEDV-QVLIPFKGRPPPT 28229 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP--- 1966 +W K GS + IEN + N G + T V K +TV Sbjct: 28230 VTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV 28289 Query: 1967 -SPPTA--PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 P A L+++ V V W P DGG+P++ Y I RD TK W V +T Sbjct: 28290 LDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSST 28349 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 F + DLSE + R+ A NEIG+ EP E+ EP K Sbjct: 28350 -SFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK 28385 Score = 190 bits (462), Expect = 5e-46 Identities = 204/900 (22%), Positives = 371/900 (41%), Gaps = 65/900 (7%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249 +E P I L + +++ A+ L V I +V W K + ++ D + + S Sbjct: 26029 IEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFT 26088 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 L+I T D Y L + T + V V++ P V+ +K+ S VTL Sbjct: 26089 M--LVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDS-VTL 26144 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGI---YKLRL 1362 + P + + + I++K + T+ + + + + T ++EN G +++ Sbjct: 26145 SWEP---PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 26201 Query: 1363 ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 N G A+ V + + P PPG+ ++++ ++ I W++PE+ G S I YVVE Sbjct: 26202 SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEM 26261 Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 Q + +W + + + +I L Y FR AVNE SD + + ++ +I Sbjct: 26262 QTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ-LGVPVIARDIEI 26320 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXX 1538 + P+VE P + E +++ F G PQ V W +DG+ LK T + + Sbjct: 26321 K-PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL 26379 Query: 1539 X---XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y+ N G + + + +P ++ + + Sbjct: 26380 SIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRP-------GPPGPIRIDEVSCDSIT 26432 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS------VIRIKELKRSHSSKYTIEASN 1649 I PP + N + KE TT S I+I L ++ + A N Sbjct: 26433 ISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 26492 Query: 1650 TAGTSSV-EVTLKVYDKPSKPEGPVIMREI---SRESVTIEWKPPLDDGGLELTKYAIEK 1705 G SS E + V + P P GP ++ ++ ++ + W+ P++DGG + Y +E Sbjct: 26493 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 26552 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTAL 1764 E + W K + + L+E Y +RV A+N G + +S EP+ + Sbjct: 26553 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 26612 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXX 1821 D P I +SV + W +GG+ I Y VE ++ +G+ K Sbjct: 26613 DPPG----QPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 26668 Query: 1822 XXARIQKLSINTTYQFRIYARNEI-GTSLPYTSDDKITIGKTLTPPSQPRNFVVSE--ST 1878 + +L+ + Y+FR++ARN S P S I + + PP + + Sbjct: 26669 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVV 26728 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE---KDE 1935 LK + P+ ++ + ++ ++ T+I+ S H + +K+ +D Sbjct: 26729 KAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII----STDNHTLLTVKDCIRRDT 26784 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 + ++ +N G T S +V K P PP PLEI + + SWG P+ DGG Sbjct: 26785 GQYVLTLKNVAG----TRSVAVNC-KVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGG 26839 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 A + Y + R+ + W + + ++ + L + + Y+ R+ N+ G+ EPLES Sbjct: 26840 ADIDYYIVEKRETSHLAW-TICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 26898 Score = 187 bits (456), Expect = 3e-45 Identities = 169/699 (24%), Positives = 289/699 (41%), Gaps = 43/699 (6%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436 KP PP P +++I SS+ + W +P G I Y+VE ++ EW I KT Sbjct: 23764 KPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKT 23823 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493 ++ L Y FR A+N+ + + ++ +I E K+++P ++ L K I Sbjct: 23824 NIEVEKLLEKHEYNFRICAINKAGVGEHADVPG--PIIVEEKLEAPDIDLDLELRKIINI 23881 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCI 1551 + L G P P+V W + +++ A + Y Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 23941 Query: 1552 AFNDHGEVETSCVVGI--QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 N G V + P + + +I K V W + G I K Sbjct: 23942 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEI-TKDSVSITWEPPLLDGGSKIKNYIVEKR 24000 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKP 1666 +T K S +I +L+ S + + A N G T +KV + P Sbjct: 24001 -EATRKSYAAVVTNCHKNS-WKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVP 24058 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 +P G + + +++R SV++ W P DGG ++ +Y +E + +W + A V + ++ Sbjct: 24059 -QPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARV-KSLQA- 24115 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 I L + EY+FRV+A N G S+ + PIV K + P + + Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 24175 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA-RIQKLSINTTY-----QFRI 1839 I S + P I + ++G K + + LSI T+ Q+ I Sbjct: 24176 IEVPISGR--PKPTITW----TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGI 24229 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 N +G S + +T+ K PP P F + ++ S+TL W P GG ITN Sbjct: 24230 TVANVVGQKT--ASIEIVTLDKP-DPPKGPVKF--DDVSAESITLSWNPPLYTGGCQITN 24284 Query: 1900 YIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 YI++ + W + TV + + + +K E FRI AEN G S ES + Sbjct: 24285 YIVQKRDTTTTVWDVVSATVARTTLK--VTKLKTGTEYQFRIFAENRYGQSFALESDPIV 24342 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 + P PP P + ++V+ W P +GG+P++GY++ ++ +W +V K Sbjct: 24343 AQYPYKEPGPPGTPFATAISKDSMVI-QWHEPVNNGGSPVIGYHLERKERNSILWTKVNK 24401 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 ++ +F ++L E Y R+YA N +G+ + ++ E Sbjct: 24402 TIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSE 24440 Score = 186 bits (453), Expect = 6e-45 Identities = 218/966 (22%), Positives = 386/966 (39%), Gaps = 81/966 (8%) Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 G+K ++ ++ EYS + ++ + +E P + L + + + A L Sbjct: 30337 GQKYSFRVAAVNVKGMSEYSESI--AEIEPVERIEIPDLELADDLKKTVTIRAGASLRLM 30394 Query: 1218 VEIPDETLDV-TWYKK------KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 V + V TW K+ +++I+ TE ++L LI+ K D +YT Sbjct: 30395 VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--------LIVDKVNRYDAGKYTIEA 30446 Query: 1271 LD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 + K + + V+V + P ++K S ++ + ++ P + VN+ I+ Sbjct: 30447 ENQSGKKSATVLVKVYDTPGPCPSV----KVKEVSRDSVTITWE-IPTIDGGAPVNNYIV 30501 Query: 1329 KKCKHTKPSIDSKSA--SLTIKKVENTDAG-IYKLRL--ENNCG---HADVEMNVTILDK 1380 +K + + + + S T+ ++ G +Y R+ EN G + V + + Sbjct: 30502 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 30561 Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QT 1438 P P K ++++ S++ + W++P G S + YV+E + T W+ V + T + Sbjct: 30562 PLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEH 30621 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEP 1495 ++ +L Y FR A NE +S+ ET +++ ++ PT++ P K I Sbjct: 30622 TVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAV-TVQDLRV-LPTIDLSTMPQKTIHVPA 30679 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCI 1551 +EL G P P +W+ G KL+ ++ T+ Y Sbjct: 30680 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 30739 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK--N 1609 N G + V I KP I DE T++ PPE+ + Sbjct: 30740 LKNVTGTTSETIKVIILDKPGPPTGPIKI-------DEIDATSITISWEPPELDGGAPLS 30792 Query: 1610 GNKLENDKEYN-----ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 G +E + ++ S + L + + + A+N G S + + Sbjct: 30793 GYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIEC 30852 Query: 1665 K-----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 + P PE I ++SR+ +T+ W PP DDGG ++T Y +E+ E +RW++V V Sbjct: 30853 RSSIRIPGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKV 30911 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXX 1778 + Y L E EY RV A N G + + S+PIV + P Sbjct: 30912 PVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPI-APPGKPQNPRVTD 30970 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXAR--IQKLSINTTY 1835 SV + W E GGS + Y +E+ K + +W + L Y Sbjct: 30971 TTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEY 31030 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNG 1893 +FR+ A N G P + + + L P + E + ++ T P Sbjct: 31031 RFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGK 31090 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 PI + E + + ++ ++ + E I+ D + + EN G + Sbjct: 31091 PFPICKWTKEGQDISKRA---MIATSETHTELVIKEADRGDSGTYDLVLENKCG----KK 31143 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 + +++ + P+ P PLE + V SW P DGGA +LGY + R+V K W Sbjct: 31144 AVYIKVRVIGS-PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAW 31202 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 + V ++ L EN Y R+ A N+ G+S+PL+S+EP V P + E P Sbjct: 31203 YTIDS-RVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEP--VTPKTPLNPPEPP 31259 Query: 2074 GEQTEV 2079 EV Sbjct: 31260 SNPPEV 31265 Score = 186 bits (452), Expect = 8e-45 Identities = 173/698 (24%), Positives = 291/698 (41%), Gaps = 41/698 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436 KP PPG P +L+ SSI+I W++P G S I Y+VE + EW V + T Sbjct: 22682 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 22741 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493 +I L N Y+ R YA+N + + + K E ++ P +E K +T Sbjct: 22742 SYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKA--EDRMLPPEIELDADLRKVVTI 22799 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRD-GKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 + L G P P+V W RD G+ L K + + + Y Sbjct: 22800 RACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILT 22859 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT---AVIEGIPPPEVIWYK 1608 N G V + P +D+K K +T +++G ++ Y Sbjct: 22860 VENSSGSKSAFVNVRVLDTPG---PPQDLKVKEVTKTSVTLTWDPPLLDG--GSKIKNYI 22914 Query: 1609 NGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVY 1663 + K Y+ T KTS ++ +L+ S + + A N G + ++K Sbjct: 22915 VEKRESTRKAYSTVATNCHKTSW-KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKAS 22973 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 ++P P G + + +++R SV++ W+ P DGG + Y +E +++W A V V Sbjct: 22974 ERPLPP-GKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVK--V 23030 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 I L + EY FRV AQN G S+ + S P++ K + P+ + E Sbjct: 23031 TEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGE 23090 Query: 1783 SVYITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 + + P + +K V +KQ + I+ + + Sbjct: 23091 DLKVD-VPFIGRPTPAVTWHKDNVPLKQTTRV-NAESTENNSLLTIKDACREDVGHYVVK 23148 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 N G ++ + I + K PP+ P + E T+ S+TL W P+ +GGS I NY Sbjct: 23149 LTNSAGEAIETLN--VIVLDKP-GPPTGPVK--MDEVTADSITLSWGPPKYDGGSSINNY 23203 Query: 1901 IIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 I+E + +W + TV + + C +K E FRI+AEN G S S+ Sbjct: 23204 IVEKRDTSTTTWQIVSATVARTTIKAC--RLKTGCEYQFRIAAENRYGKSTYLNSEPTVA 23261 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 + VP PP P+ + + + + W P DGG+ ++GY++ ++ +W+++ K Sbjct: 23262 QYPFKVPGPPGTPV-VTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKT 23320 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + KF L E Y R+ A N +G+ +P + E Sbjct: 23321 PIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE 23358 Score = 184 bits (448), Expect = 2e-44 Identities = 168/704 (23%), Positives = 281/704 (39%), Gaps = 46/704 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP P + + + ++ W +P + G S I+ YVVE Q+ T +W + I + Sbjct: 18731 PGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCA 18790 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN---ITTE 1494 + L + YRFR A N V + E E VI + + P VE + IT Sbjct: 18791 FRVPGLIEGNEYRFRIKAANIVGEGEPRELAE--SVIAKDILHPPEVELDVTCRDVITVR 18848 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YEN--RXXXXXXXXXXXXXXXYKC 1550 + I + G P+P +TW ++GK L K ++ R Y Sbjct: 18849 VGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYII 18908 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYK 1608 A N G + S +V + +P N + K W G E+ + Sbjct: 18909 SAKNSSGHAQGSAIVNVLDRPG-PCQNLKVTNVTKENCTISWENPLDNGG---SEITNFI 18964 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKV 1662 + N K ++I + T + L ++ + + A N G T + + + Sbjct: 18965 VEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINP 19024 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 D+P +PE + + + + V ++W+ P DGG Y +E+ ++ W +V Sbjct: 19025 IDRPGEPEN-LHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIK 19083 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 Y + + EN Y FRV +N G S+ +++E +V+K L P + Sbjct: 19084 ETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAG 19143 Query: 1783 SVYITWFPSEKNGGSPII----DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838 I + P + D + K + K + ++ Sbjct: 19144 DT-IRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 19202 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 + A N G+ + Y + + L P RN + + +S T+ W PE +GG I Sbjct: 19203 VTATNTAGSFVAYATVN------VLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQ 19256 Query: 1899 NYIIEFKTVKGKSWTK----IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 NYI+E K W+ ++T G +V + E +E IFR+ AEN +G PTES Sbjct: 19257 NYILEKCETKRMVWSTYSATVLTPGTTV-----TRLIEGNEYIFRVRAENKIGTGPPTES 19311 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 + V + P P P E+ V + W PE+DGG + GY + ++ T W+ Sbjct: 19312 KPVIAKTKYDKPGRPDPP-EVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWV 19370 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 V K + + +++L +H Y R+ A NEIG+ EP P Sbjct: 19371 PVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRP 19414 Score = 184 bits (448), Expect = 2e-44 Identities = 168/697 (24%), Positives = 286/697 (41%), Gaps = 35/697 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436 KP PP +I++ +SI + W +P G S I+ YVVE + D EW V + T Sbjct: 24846 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 24905 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITT 1493 + I L + Y+ R A+N+V + +A+ K E K+++P ++ + K I Sbjct: 24906 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVK--PEDKLEAPELDLDSELRKGIVV 24963 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKC 1550 + F G P P++TW R+ + T K E N Y Sbjct: 24964 RAGGSARIHIPFKGRPTPEITWSREEGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYIL 25022 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYK 1608 N G V + P N +K+ K +LV +I+G +V Y Sbjct: 25023 KLENSSGSKSAFVTVKVLDTPGPP-QNLAVKEVRK-DSAFLVWEPPIIDG--GAKVKNYV 25078 Query: 1609 NGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD--K 1665 + K Y N+++K + +++ L + + A N G T+ + Sbjct: 25079 IDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAE 25138 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P P G V + ++S+ S ++ W+ P DGG + Y +E +W VA+ V Sbjct: 25139 PPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAE--SKVCN 25196 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + L+ EY FRV A N G S+ + P++ K PS E + Sbjct: 25197 AVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 25256 Query: 1785 YITWFPSEKNGGSPIIDYKV-EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 I P I K E ++ + I++ + + ++ + A N Sbjct: 25257 KIE-IPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATN 25315 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 GT+ T + + + + PP P F E ++ V + W P GG I+NYI+E Sbjct: 25316 SAGTA---TENLSVIVLEKPGPPVGPVRF--DEVSADFVVISWEPPAYTGGCQISNYIVE 25370 Query: 1904 FKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + +W + TV + + I +K E FRI AEN G S P +S++V ++ Sbjct: 25371 KRDTTTTTWHMVSATVARTTIK--ITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYP 25428 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 P PP P + + + ++ W P DGG ++GY++ ++ +W+++ K + Sbjct: 25429 FKEPGPPGTPF-VTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 25487 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 KF L E Y ++ A N +G+ +P + E F Sbjct: 25488 DTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 25524 Score = 184 bits (447), Expect = 3e-44 Identities = 107/367 (29%), Positives = 174/367 (47%), Gaps = 6/367 (1%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G+ + A+++G P P V W+K+G ++E IT ++ + +++ R H YT Sbjct: 28898 KSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYT 28957 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 +EA N +G++ E+ +KV D P K GP+ I+ E +T+ W PL+DG +T Y IE Sbjct: 28958 VEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE 29017 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 K E W + D + ++Y KL EY FRV A N G L+S+P+V + Sbjct: 29018 KRETSRLAWALIED-KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQY 29076 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXX 1822 VP I S+ +TW E +GGS I Y +E ++ + +W K Sbjct: 29077 TVPD-APGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPIS 29135 Query: 1823 XAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 R + L+ Y+F + A N G I + + PP P V++++ Sbjct: 29136 ETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKT 29195 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 +V+L+W++P +GG I YIIE W K+ + + +++ +E FR+ Sbjct: 29196 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 29255 Query: 1941 SAENTVG 1947 SA N G Sbjct: 29256 SAINGAG 29262 Score = 183 bits (446), Expect = 4e-44 Identities = 178/727 (24%), Positives = 290/727 (39%), Gaps = 68/727 (9%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV----KNITKT 1436 P PP P + + SSI++ W P G S I Y+VE QE TT+W V K IT Sbjct: 16632 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 16691 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEP 1495 + + NLK YRFR AVNE S+ S+TT + ++ ++ + + Sbjct: 16692 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 16751 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------------ATYENRXXXXXXXXXXX 1543 I + + G P PK +W DGK K K T EN Sbjct: 16752 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 16811 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPP 1602 Y A N G+ +C V + P +D+K G L + + Sbjct: 16812 HTGKYSITAKNKAGQKTANCRVKVMDVPG---PPKDLKVSDITRGSCRLSWKMPDDDGGD 16868 Query: 1603 EVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 + Y + + K + + ++ + +L + + A N G T++ Sbjct: 16869 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16928 Query: 1662 ---VYDKPSKPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIE--KHEPDNNR-- 1712 D P+ P+ ++ I++ +V + WKPP +DGG +T Y +E +P + Sbjct: 16929 RTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKE 16988 Query: 1713 -WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 W + D + + ++ L E EY FRV A N G S+ + D+P Sbjct: 16989 AWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSID 17048 Query: 1772 XXXXXXXIDNESVYI------------TWF---PSEKNGGSPIIDYKVEIKQEGKKWKXX 1816 + +V I TWF P + + P++ Y + + Sbjct: 17049 LKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVL-YDTHVNK-------L 17100 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 I + + T + I A N +GT+ + + ++ + PP P F E Sbjct: 17101 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTA---SKEMRLNVLGRPGPPVGPIKF---E 17154 Query: 1877 STSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 S S +TL W P+ +GGS ITNY+IE + K+W + + + I + E E Sbjct: 17155 SVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHE 17213 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 +FRI A+N G+ P +S+ +VP P P + V N + +W PE+DGG Sbjct: 17214 YVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT-VSSVTRNSMTVNWEEPEYDGG 17272 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTL----KFNIRDLSENHTYMIRIYARNEIGLSE 2051 +P+ GY + ++D T W V + + + + + L E Y R+YA N G+ Sbjct: 17273 SPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGP 17332 Query: 2052 PLESDEP 2058 +P Sbjct: 17333 ASLPSDP 17339 Score = 182 bits (443), Expect = 1e-43 Identities = 246/1098 (22%), Positives = 447/1098 (40%), Gaps = 107/1098 (9%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 GI F + Q V EG C L + + + W ++ + ++ E H Sbjct: 12498 GIRLKFMSPLEDQTVKEGETATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHK 12556 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + +E T ++ + L ++K E +P ++ V + E Sbjct: 12557 L----------EMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDE 12606 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKA 807 + L +V + + W K+ + + P K+DG I +K +KD+G Y Sbjct: 12607 -ITLKCEV--SKDVPVKWFKDGEEIVPSPKYSIKADG-LRRILKIKKADLKDKGEYVCDC 12662 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 G +T A +TVE + E PL+ E+ V E ++ P W Sbjct: 12663 ----GTDKTKANVTVEARLIK-VEKPLY---GVEVFVGETAHFEIELS---EPDVHGQWK 12711 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 + ++ S DG+ L++ N + +G+ A+N+ KS+ A + + Sbjct: 12712 LKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQAANA--KSA--ANLKVKELP 12766 Query: 928 VTFVKHLQ--KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984 + F+ L K +E +E K EC+ S T +W +EI+G D E+I++G Sbjct: 12767 LIFITPLSDVKVFEKDEAK---FECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSM 12823 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D +D+ TS L+++ +F+ L+D KEK+ A+ VE++ + Sbjct: 12824 VIKSAAFEDEAKYMFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDN 12883 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W ++ + + ++ + G + ++ S+ D + S A++TV+E Sbjct: 12884 IRVKWFKNDQRLHTTRS-VSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLE 12942 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P +LQ+ + ++ + E++K DA V+WFKDG EI+ S + + DGKK+ L Sbjct: 12943 GDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLI 13002 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 + D G+Y+C+ G K + L +E+ I L ++ T + T EI ++ Sbjct: 13003 LKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFET-EISEDD 13061 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 + W K + T + + K +L++ C D + KS+ L+V+ Sbjct: 13062 IHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVK-- 13119 Query: 1285 EFPPKIVDYER---EYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 P+++ R + + G T + Y+ P EW + K ++ P + Sbjct: 13120 ---PRVIGLLRPLKDVTVTAGETATFDCELSYEDIPV---EWYLKGKKLEPSDKVVPRSE 13173 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 K +LT++ V+ DAG +L ++ HA N+ + + P KP LE Sbjct: 13174 GKVHTLTLRDVKLEDAGEVQLTAKDFKTHA----NLFVKEPPVEFTKP--LE-------- 13219 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 D+ G + ++ V +E +W KN T+ S + + + R R +++ Sbjct: 13220 --DQTVEEGATAVLECEVS-RENAKVKWF--KNGTEILKS-KKYEIVADGRVRKLVIHDC 13273 Query: 1460 ---DISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 DI + + +K + P VE +PL ++ E C KV Sbjct: 13274 TPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVK 13332 Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVI 1573 W++DG ++K K Y+ KC+ +D E E SC V + ++ Sbjct: 13333 WFKDGAEIKKGK-KYD-----IISKGAVRILVINKCL-LDD--EAEYSCEVRTARTSGML 13383 Query: 1574 TISNED-IKQKHKVGDEWLVTAVIEGI-----PPPEVIWYKNGNKLENDKEYNITTKEKT 1627 T+ E+ + K+ E T I+ + P EVIWYK ++ Y I T+ + Sbjct: 13384 TVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTEGRK 13443 Query: 1628 SVIRIKELKRSHSSKYT--IEASNTAGTSSV-EVTLKVYDKPS-----KPEGPVIMREIS 1679 ++ I+ + Y + +S T G V E+ + KP + E + IS Sbjct: 13444 RILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSIS 13503 Query: 1680 RESVTIEWKPPLDDGGLE 1697 +ES ++WK DD LE Sbjct: 13504 KESFPVQWK--RDDKTLE 13519 Score = 181 bits (440), Expect = 2e-43 Identities = 176/746 (23%), Positives = 300/746 (40%), Gaps = 44/746 (5%) Query: 795 KKVKDEGVYTLKA---ENSEGIAETSAV-ITVEEPTEENAEP----PLFINRFQEITVKE 846 +K KDE ++ K E + +AE + I +P + P P R Q TV + Sbjct: 2032 RKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQ 2091 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYK 905 RV P P WY+N I S+ I + +N+ ELVI +V +E DS Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAE-DSASIM 2150 Query: 906 CVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHN 963 A N AG++S A + + ++ +TF + LQ E+ EC+TS V KWY + Sbjct: 2151 VKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKD 2210 Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFI 1020 E+ D + + + D C++ + E T+ L+V+ + EF+ Sbjct: 2211 GMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFV 2270 Query: 1021 RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 ++LQD EV E LE ++ E + W + +K KY R + L +++ + Sbjct: 2271 KELQDIEVPESYSGELECIVSPENIEGKWYHNDVELK-SNGKYTITSRRGRQNLTVKDVT 2329 Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWF 1140 D+GEYS ++ + T ++ + P I+ L +QKV +G+ E++++ W Sbjct: 2330 KEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWM 2389 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200 KDG E+Q S+ + + ID + L I D +DAG YS + + V S++ Sbjct: 2390 KDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVIT 2449 Query: 1201 RLPEFILVPANTDAYL--TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L + + V T A L V +PD T V WY I+ ++ I K+ L+I + Sbjct: 2450 PLKD-VNVIEGTKAVLECKVSVPDVT-SVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRT 2507 Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 D+ Y ++ ++ L VE + KI+ R+ +V V+ + + Sbjct: 2508 HASDEGPYKLIVGRVETNCNLSVEKI----KIIRGLRDLTCTETQNVVFEVEL-SHSGID 2562 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 W K IK K K LT+ + D G Y N + + + Sbjct: 2563 VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAI 2622 Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 KP + E + P++ G EW+ Sbjct: 2623 SKPLT--DQTVAESQEAVFECEVANPDSKG-----------------EWLRDGKHLPLTN 2663 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 +I++ R A DI + + K + K+++ ++K LKN+T +D Sbjct: 2664 NIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKNLTVTETQD 2723 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKT 1524 T V W ++G L++ Sbjct: 2724 AVFTVELTHPNVKGVQWIKNGVVLES 2749 Score = 179 bits (436), Expect = 7e-43 Identities = 174/747 (23%), Positives = 309/747 (41%), Gaps = 47/747 (6%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 SK Q V E + + EC VA P+ WL G+ + NI ESD H ++ Sbjct: 2623 SKPLTDQTVAESQEAVFECE-VANPDSKGEWLRDGKHLPLTNNIRS--ESDGHKRRLIIA 2679 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 T + E TY V + + V KIK + LK++ V + + + + Sbjct: 2680 ATKLDDIGEYTYKVATSKTSAKLKVEAV-KIK----------KTLKNLTVTETQDAVFTV 2728 Query: 757 QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 ++ + W KN +++ G +S+ I K + DE VY + G Sbjct: 2729 ELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRI-KNCAIVDESVYGFRL----GR 2783 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 SA + VE I + +++T E T+ V+ + VP + W+ N I Sbjct: 2784 LGASARLHVETVK--------IIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEI 2834 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 PS+ + + +L++ N+ S D+G+Y V G+ A++ ++ +T Sbjct: 2835 KPSDKHRLVSERKVHKLMLQNI-SPSDAGEYTAVV----GQLECKAKLFVETLHIT---K 2886 Query: 934 LQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 K+ E E KT EC+ SH V + W N EI + +I+ +G+ Sbjct: 2887 TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTE 2946 Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 D + + + S L V + L+D +EKD EV +N E W ++ Sbjct: 2947 DSAEYTFVCGNDQVSATLTVTPIM--ITSMLKDINAEEKDTITFEVTVNYEGISYKWLKN 3004 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112 G IK +K + L IRN D +Y+ + + TA + V E Sbjct: 3005 GVEIK-STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKH 3063 Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 +++ KV + +A FE E+++ D V+W KD E+Q ++ I++ + +L I + D Sbjct: 3064 IKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123 Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 AG+Y+ G + TA L VE + + + + V A + E+ ++ +D WYK Sbjct: 3124 AGKYTVVAGGNVSTAKLFVEGRDVRIR-SIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKD 3182 Query: 1233 KSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290 I + E+ + + + + I + + D EYT V +S+ L V E PP++ Sbjct: 3183 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPE-PPQV 3241 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 + + ++ G PQP W +++ K D + +L + + Sbjct: 3242 LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEA 3301 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTI 1377 DA +Y +N+ G A ++++ Sbjct: 3302 FPEDAAVYTCEAKNDYGVATTSASLSV 3328 Score = 178 bits (434), Expect = 1e-42 Identities = 156/561 (27%), Positives = 249/561 (44%), Gaps = 26/561 (4%) Query: 804 TLKAENSEGIAETSAVITVEEPT---EENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 T+K E E S VI ++ T + P + + V E ++L +V+ Sbjct: 2324 TVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLES 2383 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 V + W ++ + + PS+ + D ++ L+I ++ E D+G+Y + G S+ G Sbjct: 2384 VEGV-WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKE-DAGNYSFTIP-ALGLSTSGRV 2440 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQE 978 V+ +T +K + EG +LEC+ S S KWY N ++I D + I + Sbjct: 2441 SVYSVDVITPLKDVN----VIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2496 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 G D G K IV ET+ L V++ + IR L+D E + EV Sbjct: 2497 GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI--KIIRGLRDLTCTETQNVVFEV 2554 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 E++ DV+W + IKP +KY E G I KL + N DEG+Y+ + + Sbjct: 2555 ELSHSGIDVLWNFKDKEIKPS-SKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSG 2613 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158 ++TV I L +Q V + +A FE E+ D+ W +DG + +N+I+ DG Sbjct: 2614 KLTVAG--GAISKPLTDQTVAESQEAVFECEVANPDSKGEWLRDGKHLPLTNNIRSESDG 2671 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 K++L I LDD GEY+ +V SK +A L VE I TL+ + V DA TV Sbjct: 2672 HKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLK---NLTVTETQDAVFTV 2728 Query: 1219 EIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 E+ + V W K V+E EK+ + +L I+ C D+ Y L ++ Sbjct: 2729 ELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASA 2788 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 +L VE V KI+ ++ + V V P + N +I KH S Sbjct: 2789 RLHVETV----KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIKPSDKHRLVS 2844 Query: 1338 IDSKSASLTIKKVENTDAGIY 1358 + K L ++ + +DAG Y Sbjct: 2845 -ERKVHKLMLQNISPSDAGEY 2864 Score = 178 bits (434), Expect = 1e-42 Identities = 153/697 (21%), Positives = 291/697 (41%), Gaps = 36/697 (5%) Query: 1382 SPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436 +PPG P ++++ +S +++ W +P G II Y++E + D +W ++ + KT Sbjct: 29179 NPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT 29238 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEP 1495 + ++ +L+ Y+FR A+N D+ E T K + ++ K Sbjct: 29239 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRA 29298 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAF 1553 I L + G P P W + L T ++ Y Sbjct: 29299 GASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVE 29358 Query: 1554 NDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKN 1609 N+ G + V + P I+ +D+ + G L+ +++G + Y Sbjct: 29359 NNSGSKSITFTVKVLDTPGPPGPITFKDVTR----GSATLMWDAPLLDG--GARIHHYVV 29412 Query: 1610 GNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDK 1665 + + + + + +++ T + ++ +L + + A N G + + ++ Sbjct: 29413 EKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQ 29472 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P+ P ++ + S+ S + W P DGG +T Y +E + ++ W++ + T Sbjct: 29473 PAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQ--LT 29529 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + +++L E EY FRV A+N G+SE E+ ++IK P+ I ++ Sbjct: 29530 FTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAG 29589 Query: 1785 YITWFPSEKNGG-SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 +G +P + +K+E + E + ++ + ++ + Sbjct: 29590 SPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTL 29649 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N G S + IG+ P + P VS ++ S L W EP+ GG+ ITNYI Sbjct: 29650 ENTAGVKT--FSVTVVVIGRP-GPVTGP--IEVSSVSAESCVLSWGEPKDGGGTEITNYI 29704 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +E + +W ++V + + ++ + E FR+S+EN GVS P ES + E Sbjct: 29705 VEKRESGTTAW-QLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEH 29763 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 PS PT P E+ V +N + W P DGG+ ++GY + ++ +W++ KV Sbjct: 29764 PFVPPSAPTRP-EVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC 29822 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + L E Y R YA N G+S+ E+ P Sbjct: 29823 LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRP 29859 Score = 178 bits (433), Expect = 2e-42 Identities = 212/908 (23%), Positives = 369/908 (40%), Gaps = 68/908 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTW------YKKKSVIEDTEKFTLIS 1246 P L ++V A + V I +VTW K ++ IE+TE FTL Sbjct: 21701 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL-- 21758 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304 LII +C D ++ + + K + + V V++ P +++ R I + S Sbjct: 21759 ------LIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNL-RPTDITKDS- 21810 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAG---IYK 1359 VTL D P + + + I++K + T+ S + + KV G ++ Sbjct: 21811 VTLHWD---LPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFR 21867 Query: 1360 LRLENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 + EN G + V + PSPP NI++I S++++ W +P++ G S I YV Sbjct: 21868 VMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYV 21927 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E Q + +W + + + ++NL Y F+ AVN S E+ ++KE Sbjct: 21928 IEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPV--IVKE 21985 Query: 1477 TKIQSPTVEKPL--KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRX 1533 + + + K + + ++I++ G P+P VTW + + LK T + +E Sbjct: 21986 QTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTA 22045 Query: 1534 XXXXXXX---XXXXXXXYKCIAFN---DHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 Y A N + G+V T V I P I +++ V Sbjct: 22046 TSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDF-VT 22104 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 W G+P + + ++ + T + + L ++ ++A Sbjct: 22105 FSWDPPENDGGVPISNYV--VEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKA 22162 Query: 1648 SNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 N G TS+ V + P P P + ++++S+TI W PL DGG + Y Sbjct: 22163 QNRYGVGPGITSACIVANYPFKVPGPPGTPQV-TAVTKDSMTISWHEPLSDGGSPILGYH 22221 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761 +E+ E + W V+ + L + Y FRVIA+N G S+ + SEP++ Sbjct: 22222 VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLAL 22281 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXX 1819 +D P I +V + W E GG I Y VE + G+ K Sbjct: 22282 DPIDPPG----KPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSN 22337 Query: 1820 XXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 + L+ + Y+FR+ A+N G S P D IT + P + ++ Sbjct: 22338 ILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDT 22397 Query: 1878 TSRSVTLKW-TEPESNGGSPIT-NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + E + +G P T + + K ++G + +I S + ++ +D Sbjct: 22398 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-LVNKDSTRRDS 22456 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 + ++A N G + + V L++ P PP PL + V S + SW P DGG Sbjct: 22457 GAYTLTATNPGGFAKHIFNVKV-LDR----PGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 22511 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 A + Y + R+ ++ W V +V K + L + + Y+ R+ A N+ G+ EPLES Sbjct: 22512 AKIDHYIVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 22570 Query: 2056 DEPFKVIP 2063 + V P Sbjct: 22571 EPVLAVNP 22578 Score = 177 bits (432), Expect = 2e-42 Identities = 242/1060 (22%), Positives = 407/1060 (38%), Gaps = 87/1060 (8%) Query: 645 VDEGSDILLECRLVAIPE-PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V EG+ +LEC+ V++P+ + W E+I PD+ + ++ L I Sbjct: 2456 VIEGTKAVLECK-VSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQR----LVINRTHAS 2510 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 EG Y ++ E +L + KIK +I L+ + + ++V+ ++ + Sbjct: 2511 DEGPYKLIVGRVETNCNLSVE-KIK--------IIRGLRDLTCTETQNVVFEVEL-SHSG 2560 Query: 764 PTITWC---KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W K KP ++ G + +T+L K DEG YT A E I TS + Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMK-DDEGKYTFYA--GENI--TSGKL 2615 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 TV PL + TV E V NP W R+ + + + I Sbjct: 2616 TVAGGA---ISKPL-----TDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIR 2666 Query: 881 QNFDGENIELVI--TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 DG L+I T +D +I YK S ++ K + VE V K L+ Sbjct: 2667 SESDGHKRRLIIAATKLD-DIGEYTYKVATSKTSAK--------LKVEAVKIKKTLKNLT 2717 Query: 939 ETEEGKTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 TE V +E + +W N + + I +G D V Sbjct: 2718 VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVY 2777 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 + S L V ET+ + I+K +D E EV ++ +T V W IK Sbjct: 2778 GFRLGRLGASARLHV-ETV-KIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKNVEIK 2835 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 P +K+ + KL ++N S D GEY+ ++ C A++ V L I ++N + Sbjct: 2836 PS-DKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVETL--HITKTMKNIE 2892 Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 V + A+FE E++ + W K+G EI+ S ++ + GK +L I + +D+ EY+ Sbjct: 2893 VPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2952 Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237 GN + +A LTV I T L + +T + V + E + W K I+ Sbjct: 2953 FVCGNDQVSATLTVTP--IMITSMLKDINAEEKDTITF-EVTVNYEGISYKWLKNGVEIK 3009 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYER 1295 T+K + + +L IR D +YT V A ST L VE +EF I D + Sbjct: 3010 STDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI-K 3068 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 KR + + P +W+ + + ++ K + L I +DA Sbjct: 3069 VLEKKRAMFECEVSE----PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 G Y + N A + + + S + ++E + + +E + + Sbjct: 3125 GKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGI 3184 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 + +Q + +++ + I + S Y F A + S T Y Sbjct: 3185 EINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-------NRSSVTLYVNAP- 3236 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENR 1532 + P V + L+ +T + + + G PQPK++WY++ + L T K ++ + Sbjct: 3237 ----EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQ 3292 Query: 1533 XXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C A ND+G TS + ++ V++ E + Sbjct: 3293 EYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQ 3352 Query: 1592 VTAVIEGIPPP----------EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 T EG P +V WY K++ + + +T E T + I E Sbjct: 3353 DTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEG 3412 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 YT ASN G S L + + P I +EI E Sbjct: 3413 TYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEME 3451 Score = 176 bits (429), Expect = 5e-42 Identities = 155/678 (22%), Positives = 278/678 (41%), Gaps = 27/678 (3%) Query: 712 AVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 A+ EG+ ++P K + E P++ E ++S V QG +VVG P P W Sbjct: 2052 ALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEW 2111 Query: 769 CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 KN ++ + D +++ +D +KA N G + A + V+ Sbjct: 2112 YKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA- 2170 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 + F Q++ KEK T+ T P + WY++ + + + D Sbjct: 2171 ----KQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDR 2226 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 + L I +D+ D+ DY CV + A++ ++ V FVK LQ E E + Sbjct: 2227 KVHFLSILTIDTS-DAEDYSCVLVEDENVKT-TAKLIVEGAVVEFVKELQ-DIEVPESYS 2283 Query: 946 VILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 LEC S + KWYHN E+ I D G ++ + Sbjct: 2284 GELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGK 2343 Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY- 1063 +T+ L +K ++ L D +V E D+ LEV+++ E+ + VW +DG+ ++P + Sbjct: 2344 KTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHI 2403 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 +K+ H+ L I + + D G YS + + V ++IT L++ V +G K Sbjct: 2404 VIDKQSHM--LLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTK 2461 Query: 1124 ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 A E +++ D V+W+ + +I+ + +Q + G KQ+L I D G Y VG Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGR 2521 Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242 + L+VE+ I LR + + VE+ +DV W K I+ + K+ Sbjct: 2522 VETNCNLSVEKIKIIRGLR---DLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKY 2578 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 + + K L + +DD+ +YT + ++ KL V + D + Sbjct: 2579 KIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTD----QTVAES 2634 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 + + A P EW+ + K + + + D L I + D G Y ++ Sbjct: 2635 QEAVFECEV-ANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKV 2693 Query: 1363 ENNCGHADVEMNVTILDK 1380 + A +++ + K Sbjct: 2694 ATSKTSAKLKVEAVKIKK 2711 Score = 176 bits (429), Expect = 5e-42 Identities = 171/705 (24%), Positives = 309/705 (43%), Gaps = 56/705 (7%) Query: 632 IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 IPP+F+K+ + EG+ LE R+ +AW EI P N + +++ Sbjct: 9174 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNT-- 9231 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 VL++ G YT N G A + IK K+PP + L + V +GE Sbjct: 9232 --LVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE-PKKPPVFDQHLTPVTVSEGE 9288 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808 V LS V G+ I W K + +K S +L+ + V D G Y KA Sbjct: 9289 YVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKAS 9348 Query: 809 NSEGIAETSAVITVEE-----PTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNP 860 N G T + +T+++ P + A F++ Q I V EK T +A+V +P Sbjct: 9349 NVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 9408 Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 +P++ W + ++ + + G+ +L I + ++ DSG Y+CVA N G+ Sbjct: 9409 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDT-TKTDSGLYRCVAFNEHGEIESNV 9467 Query: 920 RVTIDV----EKV-----TFVKH--LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 + +D EK+ +K + K EE + I+E + V K Y + Sbjct: 9468 NLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKN--VDPKEYEKYARMY 9525 Query: 969 GM-DHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLV------VKETIP-EF 1019 G+ D R ++Q ++ I+ +D++ LV + +T P Sbjct: 9526 GITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTL 9585 Query: 1020 IRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 I+ +++ V + + A+ E++I N + W + E ++P +K++ G L ++ Sbjct: 9586 IKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPS-DKFEISIDGDRHTLRVK 9644 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 N + D+G Y + +A++TV+E P LQ+ + +G T + + + Sbjct: 9645 NCQLKDQGNYRLVCGPHIASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSVPNVKS 9702 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 WF++G ++ + ++ K KL I D +D G+Y+C+ + + +A L +E I Sbjct: 9703 EWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQ 9762 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 FT R+ + I+V + A E+ + VTWYK + + +++K+ +D + + I Sbjct: 9763 FTKRI-QNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHN 9821 Query: 1258 CTEDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292 T DD+ Y+ + +A+ST +L + E PP I D Sbjct: 9822 VTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPD 9866 Score = 174 bits (424), Expect = 2e-41 Identities = 197/865 (22%), Positives = 337/865 (38%), Gaps = 48/865 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV 1284 VTW KK+ T+ ++ V + L IR +D Y+ + + T +KV V+ Sbjct: 18177 VTW-KKEDRDAPTKARIDVTPVGSK-LEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 18234 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P D E K +T ++V + + + + S SK S Sbjct: 18235 DKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKS 18294 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL---EIDSSSIN 1398 K + + ++++ EN G + + LD PPG P L ++D + ++ Sbjct: 18295 HFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVS 18354 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 + W++P+ G S I Y+VEYQE T +WI K +T + + L+ +YRFR A N Sbjct: 18355 LVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 18414 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 V + +TT + + K+ P+VE K ++ + + + I GVP P W Sbjct: 18415 VGLG-LPDTT--IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKW 18471 Query: 1516 YRDGKKLKTAK-ATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETS---CVVGIQ 1568 DG ++KT + T E Y+ N G + V+ + Sbjct: 18472 TTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP 18531 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 P I+ D+ +H + W G P I K + D +++ + Sbjct: 18532 GPPTGPINILDVTPEH-MTISWQPPKDDGGSPVINYIVEKQDTR--KDTWGVVSSGSSKT 18588 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGT----SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 ++I L++ + + A N G S K P P G ++ +I+ + T Sbjct: 18589 KLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT 18648 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + W P DGG +T Y +E+ E +W++V + + L E Y FRV A+ Sbjct: 18649 VSWTLPKSDGGSPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAE 18707 Query: 1745 NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G S+ + S+PI + P E+ + W +GGSPI+ Y Sbjct: 18708 NLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDK-SRETADLVWTKPLSDGGSPILGYV 18766 Query: 1804 VEIKQEG-KKWKXXXXXXXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 VE ++ G +W R+ L Y+FRI A N +G P + + Sbjct: 18767 VECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIA 18826 Query: 1860 GKTLTPPSQPRNFVVSESTSRSV--TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 L PP + + + V T++ P + E K + + ++ Sbjct: 18827 KDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQ 18886 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 V E I+ D + ISA+N+ G +Q + P P L++ Sbjct: 18887 DLPRV-ELQIKEAVRADHGKYIISAKNSSG-----HAQGSAIVNVLDRPG-PCQNLKVTN 18939 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 V SW P +GG+ + + + R + W V DV T + +L N+ Y Sbjct: 18940 VTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVAS-DV-TKRLIKANLLANNEY 18997 Query: 2038 MIRIYARNEIGLSEPLESDEPFKVI 2062 R+ A N++G+ +E+ P I Sbjct: 18998 YFRVCAENKVGVGPTIETKTPILAI 19022 Score = 171 bits (415), Expect = 2e-40 Identities = 164/708 (23%), Positives = 296/708 (41%), Gaps = 36/708 (5%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT 1436 +D P PPGKP + ++ +S+ + W +PE+ G + I YV+E + T EW+ V + + T Sbjct: 14908 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 14967 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEP 1495 Q + L Y FR AVN+ S+ SE ++ V+ K+ P+ + L+ I T+ Sbjct: 14968 QHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD--PVLCREKLYPPSPPRWLEVINITKN 15025 Query: 1496 NEDIELTCIF--GGVPQPK-VTWYRDGKKL------KTAKATYENRXXXXXXXXXXXXXX 1546 D++ T GG P + RD ++ T K T Sbjct: 15026 TADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVA 15085 Query: 1547 XYKCIAFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 I +D+ E+E S + P ++ D+ ++H V +W G P Sbjct: 15086 AENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQR 15144 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTL 1660 + K +L T R+ ++ ++ + A N AG S L Sbjct: 15145 YVIEKK-ERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 15203 Query: 1661 KVYDKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 + D S P P+ + + R+ + I WKPP +GG + Y +E +W++V Sbjct: 15204 SIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 15263 Query: 1719 VD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXX 1776 +D++ + + + EY+ RV A N +G SE E SE +V K P+ Sbjct: 15264 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDI 15323 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQ-KLSINTTY 1835 I+ E + I P + P + + + K+ + A ++ S+ Sbjct: 15324 IVIEGEKLSIP-VPF-RAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 15381 Query: 1836 Q-FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 + I N++G++ T+ + K + P ++ S+ T S L W PE +GG Sbjct: 15382 GIYTITLENKLGSA---TASINV---KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGG 15435 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 +PI +Y++E + +++ +++ G + ++++ E FR+ A N VG E Sbjct: 15436 TPILHYVLERREAGRRTYIPVMS-GENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL 15494 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 ++ + + P P +E+ + + +W P +DGG+ ++GY I + W Sbjct: 15495 KNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWK 15554 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 + V L + + L E Y R+ A N G+SEP + P K + Sbjct: 15555 RCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV 15602 Score = 166 bits (404), Expect = 5e-39 Identities = 246/1096 (22%), Positives = 440/1096 (40%), Gaps = 86/1096 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P ++ ++Q V +GSD R+V P+P+ W G +I + I D C Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPED--NVCE 2135 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I +V + V A+N GE S L ++ K+ + L+ ++ ++ +++ Sbjct: 2136 -LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA--KQLITFTQELQDVVAKEKDTMA 2192 Query: 754 LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 P + W K+ V SD H ++IL D Y+ Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL-TIDTSDAEDYSCVLVED 2251 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 E + +T+A + VE E F+ Q+I V E + +L V+ + WY N+ Sbjct: 2252 ENV-KTTAKLIVEGAVVE------FVKELQDIEVPESYSGELECIVSPENIEG-KWYHND 2303 Query: 871 -EIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 E+ S + TIT +N L + +V E D G+Y V GK + ++ + + Sbjct: 2304 VELKSNGKYTITSRRGRQN--LTVKDVTKE-DQGEYSFVID---GKKT-TCKLKMKPRPI 2356 Query: 929 TFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 ++ L + EG V LE + S +V W + +E+ D I+ + + Sbjct: 2357 AILQGL-SDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046 D G + ST V + I L+D V E A+LE +++ + Sbjct: 2416 DMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTS 2475 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 V W + E IKP ++ +G ++L I T DEG Y I+ ++V ++ Sbjct: 2476 VKWYLNDEQIKP-DDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI- 2533 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRW-FKDGSEIQFSNHIQLTIDGKKQKLKI 1165 +II L++ + FE+EL+ V W FKD EI+ S+ ++ GK KL + Sbjct: 2534 -KIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKD-KEIKPSSKYKIEAHGKIYKLTV 2591 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 + DD G+Y+ G + + LTV +I+ L V + +A E+ + Sbjct: 2592 LNMMKDDEGKYTFYAGENITSGKLTVAGGAISKPLTDQ---TVAESQEAVFECEVANPDS 2648 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 W + + T SD KR LII DD EYT + +K++ KLKVE V Sbjct: 2649 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAV- 2707 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 KI + + D V+ +WI N +++ + S+ SL Sbjct: 2708 ---KIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSL 2764 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 IK D +Y RL A + + V I+ KP ++ ++++++ Sbjct: 2765 RIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPK-----DVTALENATVAFEVSVS 2819 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 +T + VE + D +S + + K +QN+ + + + A V +++ Sbjct: 2820 HDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLM--LQNISPSDAGEYTA-VVGQLECK-- 2874 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 K+ ET + K +KNI + C P + W ++G +++ Sbjct: 2875 ------AKLFVETL----HITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEM 2923 Query: 1525 A---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 + K + + Y + ND +V + V +IT +DI Sbjct: 2924 SEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND--QVSATLTV---TPIMITSMLKDI 2978 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 + K + VT EGI W KNG ++++ + + TK+ T + I+ + + Sbjct: 2979 NAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDA 3035 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYD--------KPSKPEGPVIMREISRESVTIEWKPPLD 1692 + YT A T+++ V + + K + + + E+S +T++W D Sbjct: 3036 ADYTFVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMK--D 3093 Query: 1693 DGGLELT-KYAIEKHE 1707 D L++T + I+K + Sbjct: 3094 DQELQITDRIKIQKEK 3109 Score = 165 bits (401), Expect = 1e-38 Identities = 188/777 (24%), Positives = 330/777 (42%), Gaps = 67/777 (8%) Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 +P+ EWIV + ++ CK+ S+T K +E + ++++R EN G ++ Sbjct: 15772 KPDSEWIVVTSTLRHCKY----------SVT-KLIEGKEY-LFRVRAENRFGPGPPCVSK 15819 Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++ K P P KP + ++ S+S+ + W+EP++ G S I+ Y +E +E+++T W V Sbjct: 15820 PLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG-SPILGYWLEKREVNSTHWSRV 15878 Query: 1431 KN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 + + ++ L +Y FR A N S ++ P + + Sbjct: 15879 NKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT 15938 Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXX 1544 +T + E GG ++ Y K+L + ++ T + Sbjct: 15939 DTSSTTIELEWEPPAFNGG---GEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIRE 15995 Query: 1545 XXXYKC--IAFNDHGEV---ETSCV-VGIQQKPVITISNEDIKQKHKV--GDEWLVTAVI 1596 YK A N GE ET V V Q+P + +K ++ G + AV+ Sbjct: 15996 GADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVV 16055 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P P +W K +L+ D+ K+ +I IK+ R +Y I A+N+ G+ Sbjct: 16056 TGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELI-IKDALRKDHGRYVITATNSCGSKFA 16114 Query: 1657 EVTLKVYDKPSKPEGPVI-MREI--SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 ++V+D P GPV+ ++ + +R+ + W P DDGG E+T + IE+ + + W Sbjct: 16115 AARVEVFDVP----GPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTW 16170 Query: 1714 IKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772 + + +R + C I L E EY FRVIA+N G +E PI+ L P+ Sbjct: 16171 RQPIETER---SKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPER 16227 Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829 ++ + W NGGSPI Y +E ++ K + ++ L Sbjct: 16228 LTYTER-TKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENL 16286 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 + Y+FR+ A NEIG S P + + + P + R V ++ P Sbjct: 16287 DEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIP 16346 Query: 1890 ESNGGSPI-------TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 G P+ +IE T + + V+ + E I +D+ + ++A Sbjct: 16347 ADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTA 16406 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 N +G + ++V +E + PSPP L + + + +W P +GG+ + Y Sbjct: 16407 SNRLG----SVFRNVHVEVYDR-PSPP-RNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 16460 Query: 2003 IAIRDVT--KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 I RD + K W EV V ++ I L N Y R+ A N+ G+S+ +SD+ Sbjct: 16461 IDKRDASRKKAEWEEVTNTAVEK-RYGIWKLIPNGQYEFRVRAVNKYGISDECKSDK 16516 Score = 165 bits (401), Expect = 1e-38 Identities = 221/972 (22%), Positives = 399/972 (41%), Gaps = 75/972 (7%) Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY-SCEV-GNSKC 1185 IE+ K D L W K +E +T ++ K ++ AG+ SCEV G K Sbjct: 29217 IEMCKAD-LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKA 29275 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245 LT E I+ + + A+ ++ + T W K S + + + + Sbjct: 29276 VDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ-GRPTPTAVWSKPDSNL--SLRADIH 29332 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLD---AKSTT-KLKVEVVEFPPKIVDYEREYRIKR 1301 + TL + C +D +YT + + +KS T +KV PP + ++ + R Sbjct: 29333 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD---VTR 29389 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASLTIKKVENTDAGI-- 1357 GS TL+ D P + ++ +++K + ++ S + S+ + I KV + G+ Sbjct: 29390 GS-ATLMWDA---PLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPY 29445 Query: 1358 -YKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 +++ N G + EM I+ ++P+PP + ++++ SS + W +P++ G S I Sbjct: 29446 YFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRIT 29505 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 Y++E ++ + W+ + + +++ L + Y FR A N+ S+ E + Sbjct: 29506 GYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV-I 29564 Query: 1474 IKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK----TAKA 1527 IKE +I+ + N IT + + G P PKVTW + +LK + Sbjct: 29565 IKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSIT 29624 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 T ++R Y N G S V + +P ++ V Sbjct: 29625 TTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVS---SVS 29681 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKY--- 1643 E + V+ P + + N + +E T + S ++ ++K +H +KY Sbjct: 29682 AE---SCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEY 29738 Query: 1644 --TIEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + + N G S + + + PS P P + +S +++I W+ P DGG Sbjct: 29739 SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVY-HVSANAMSIRWEEPYHDGGS 29797 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755 ++ Y +EK E + W+K V Y + L E EY FR A N G S+A E S Sbjct: 29798 KIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 29857 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---- 1811 PI+ + +D P + +V + W +GGS ++ Y +E K + Sbjct: 29858 RPIMAQNPVDAPG----RPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDG 29913 Query: 1812 KWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQ 1868 +W + LS TY+FR+ A+N G S S +T PP Sbjct: 29914 RWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKA 29973 Query: 1869 PRNF-VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV--GGSVHEH 1925 + + + + + GG P II K K + V++ G Sbjct: 29974 ELDARLHGDLVTIRAGSDLVLDAAVGGKPEPK-IIWTKGDKELDLCEKVSLQYTGKRATA 30032 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNIVM 1984 I+ D + ++ +N G T++ SV ++ + SP P L + V Sbjct: 30033 VIKFCDRSDSGKYTLTVKNASG----TKAVSVMVK---VLDSPGPCGKLTVSRVTQEKCT 30085 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 +W P+ DGGA + Y + R+ ++ W+ V + + TL + + L +N+ Y+ R+ A Sbjct: 30086 LAWSLPQEDGGAEITHYIVERRETSRLNWVIV-EGECPTLSYVVTRLIKNNEYIFRVRAV 30144 Query: 2045 NEIGLSEPLESD 2056 N+ G P+ES+ Sbjct: 30145 NKYGPGVPVESE 30156 Score = 163 bits (395), Expect = 6e-38 Identities = 179/733 (24%), Positives = 293/733 (39%), Gaps = 51/733 (6%) Query: 1358 YKLRLENNCGHADVEMN---VTILDKPSPPGKP-NILEIDSS--SINICWDEPENTGNST 1411 ++++ EN G + + V D PPG P N +D++ SI + W +P G + Sbjct: 19395 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 19454 Query: 1412 IIYYVVEYQE--IDTTE---W---ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 II YVVE + D + W + + + + ++ +L N Y FR A N+V I Sbjct: 19455 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 19514 Query: 1464 ASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--- 1517 +E E K KE ++ P ++ K + I L I G P PKVTW + Sbjct: 19515 PAELKEAIKP-KEI-LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGI 19572 Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITI 1575 D K + Y N GE V + PV + Sbjct: 19573 DNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDL 19632 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKE 1634 D+ K W A E +V Y + + K ++ T E K + + Sbjct: 19633 KVSDV-TKTSCHVSW---APPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTN 19688 Query: 1635 LKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKP 1689 L + + + A N G + V + D S+P+ P + + E+++ S T+ W P Sbjct: 19689 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 19748 Query: 1690 PLDDGGLELTKY--AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 PL DGG ++ Y + + E +RW + + V +D+ + + L E +Y FRV A+N V Sbjct: 19749 PLRDGGAKIDGYITSYREEEQPADRWTEYS-VVKDL-SLVVTGLKEGKKYKFRVAARNAV 19806 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G S E+E + +P + + I K P +K Sbjct: 19807 GVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK--PHPTCKWKKGED 19864 Query: 1808 Q--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 + I+ ++ + + + A N GT T K+ + P Sbjct: 19865 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTD---TQKIKVVVMDAPGP 19921 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P F +S+ + + +L W P +GGS ITNYI+E V W + + Sbjct: 19922 PQPP--FDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDW--VTALASVTKTS 19977 Query: 1926 C-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 C + + E IFR+ AEN G+S P S + + VPS P + V + + Sbjct: 19978 CRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP-KNARVTKVNKDCIF 20036 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 +W P+ DGG+P++GY I ++ +W++ V + ++ L E Y RIYA Sbjct: 20037 VAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 20096 Query: 2045 NEIGLSEPLESDE 2057 N+ G S P + E Sbjct: 20097 NKAGSSPPSKPTE 20109 Score = 162 bits (393), Expect = 1e-37 Identities = 159/704 (22%), Positives = 283/704 (40%), Gaps = 35/704 (4%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITK 1435 +++PSPP + SS+ + W+ P G S I+ Y++E E WI ++K + + Sbjct: 14216 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 14275 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE- 1494 + L+ + Y +R A N+ +SD SE + + PT++ E Sbjct: 14276 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILG--PLTADDAFVEPTMDLSAFKDGLEV 14333 Query: 1495 --PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 PN I + G P+P TW K L+T K I Sbjct: 14334 IVPNP-ITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI- 14391 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-----VIWY 1607 + E + G + V I+ ++ K GD + + PP + + Y Sbjct: 14392 YTLKLENRVKTISG--EIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGY 14449 Query: 1608 KNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVY 1663 + + K + T + + +L + + + A N G V+ + + Sbjct: 14450 VVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMS 14509 Query: 1664 DKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 + P+ P V R+ + S+ + W PP +DGG + Y +E+ +++W+ + Sbjct: 14510 TPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA 14569 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID 1780 + + + L E Y +RV A N G S+ + +E I + P + Sbjct: 14570 ETKME-VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 14628 Query: 1781 NESVYITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 ++ P+ G P I + K + I ++ K+ I + T + Sbjct: 14629 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 14688 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 I A N G + T+ ++ + L P P F +++ T+ S L W P +GGS I Sbjct: 14689 IIEAVNVCGRA---TAVVEVNV---LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKI 14742 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 TNY++E + + W K+ + + + I K E IFR++AEN GV P ++ + Sbjct: 14743 TNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNK-EYIFRVAAENMYGVGEPVQASPI 14801 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + P PPT LE + + V +W P+ DGG+P+ GY + D W+ Sbjct: 14802 TAKYQFDPPGPPTR-LEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN 14860 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 K+ V + ++ L+ Y R+ A N G +P +S EP + Sbjct: 14861 KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 14904 Score = 161 bits (391), Expect = 2e-37 Identities = 238/1087 (21%), Positives = 450/1087 (41%), Gaps = 84/1087 (7%) Query: 629 LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVA 683 L+ +P F K+ K + E GS + EC LV+ W+ G I ++ +A Sbjct: 12037 LKAVPLKFVKEIKDIILTESEFVGSSAIFEC-LVSPSTAITTWMKDGSNIRESPKHRFIA 12095 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741 D ++ I +V+ G YT V N+E ++ +V+ E+ P + ++ L Sbjct: 12096 DGKDRKLH-----IIDVQLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTL 12145 Query: 742 KSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796 + + V +G+ + LS ++ N + W K+ K V P + G ++TI Sbjct: 12146 EEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADD 12203 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 D G YT+ EN+ + +S V VE + +P ++ VK KGT + Sbjct: 12204 T-DAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP------IRDQHVKPKGTAIFACDI 12256 Query: 857 TRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 ++ P+I W++ + I P++ DG ++ L I N E D +Y A GK Sbjct: 12257 AKD-TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPE-DIAEY---AVEIEGK 12311 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973 + A++T+ +V +K ++ E ++ + + S + +W + + Sbjct: 12312 R-YPAKLTLGEREVELLKPIE-DVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTC 12369 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 EI EG G + + T+ +L VKE +F L+D V E+ Sbjct: 12370 EIKAEGGKRFLTLRKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERRQ 12429 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 A E + E A+V+W + +IIK +K+D G L I ++ DEG Y+ + Sbjct: 12430 ARFECVLTRE-ANVIWSKGPDIIK-SSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEG 12487 Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 + +A + V + + ++ L++Q V +G ATF EL+ V WFK+ +++ S + Sbjct: 12488 KKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVL 12547 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 ++ +GK KL++ + LDD + +V TA L V E FT++L + V + + Sbjct: 12548 ISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKD-E 12606 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 L E+ + + V W+K I + K+++ +D +R L I+K D+ EY C Sbjct: 12607 ITLKCEV-SKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTD 12665 Query: 1274 KSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQ-AFPQPNDEWIVNSKIIKKC 1331 K+ + VE +++ E+ Y ++ T + + + P + +W + + + Sbjct: 12666 KTKANVTVEA-----RLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTAS 12720 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + D K L + + G + N A++++ L +P + E Sbjct: 12721 PDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFE 12780 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQN--LKTNSS 1448 D + E E + ++ QEI + +K+ TK I++ + + Sbjct: 12781 KDEAKF-----ECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAK 12835 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 Y F A + T +I+ +++ T PLK++T + E T Sbjct: 12836 YMFEA----------EDKHTSGKLIIEGIRLKFLT---PLKDVTAKEKESAVFTVELSH- 12881 Query: 1509 PQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 +V W+++ ++L T ++ + ++ I G + + + Sbjct: 12882 DNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL 12941 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 + P T +D K DE ++ I P V W+K+G +++ K I K Sbjct: 12942 EGDPYFTGKLQDYTGVEK--DEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK 12998 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI-SRESVTIE 1686 ++ +K+ +S +YT + GT L + D+ K P+ E+ E+ E Sbjct: 12999 RMLILKKALKSDIGQYTCD----CGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFE 13054 Query: 1687 WKPPLDD 1693 + DD Sbjct: 13055 TEISEDD 13061 Score = 161 bits (390), Expect = 3e-37 Identities = 169/711 (23%), Positives = 284/711 (39%), Gaps = 48/711 (6%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITK 1435 LD PPGKP L I ++ + W +PE TG I Y+VE +++ W+ NI + Sbjct: 22281 LDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 22340 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLK---NI 1491 + ++ L +++Y FR A N IS SE ++ + +++P ++ +K + Sbjct: 22341 NEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD--AITCRDDVEAPKIKVDVKFKDTV 22398 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXX---XXX 1547 + E L G P P + W +DGK+L+ TAK + Sbjct: 22399 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGA 22458 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y A N G + V + +P E +V E V+ PP + Sbjct: 22459 YTLTATNPGGFAKHIFNVKVLDRPG---PPEGPLAVTEVTSE---KCVLSWFPPLDDGGA 22512 Query: 1608 KNGNKLENDKEY------NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-----SSV 1656 K + + +E N+ ++ + + +++ +L + + + + A N G S Sbjct: 22513 KIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 22572 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 + + Y P P+ P + I+++S+ + W P DGG E+ Y +E+ + RWIK Sbjct: 22573 VLAVNPYGPPDPPKNPEVTT-ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKC 22631 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 Y + L E EY FR++A+N G S + P Sbjct: 22632 NKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRV 22691 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXAR---IQKLSIN 1832 S+ I W +GGS I Y VEI E +W+ A I L+ N Sbjct: 22692 LDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTEN 22751 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES-TSRSV-TLKWTEPE 1890 Y+ RIYA N G P + PP + + + T R+ TL+ P Sbjct: 22752 QEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPI 22811 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-NIKEKDEIIFRISAENTVGVS 1949 +P + + G+S K S + I N+ D + ++ EN+ G Sbjct: 22812 KGRPAPEVKWARDH----GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG-- 22865 Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 ++S V + T P PP L+++ V V +W P DGG+ + Y + R+ T Sbjct: 22866 --SKSAFVNVRVLDT-PGPPQ-DLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 22921 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + + V + + + + L E +Y R+ A NE G+ P E+ E K Sbjct: 22922 RKAYSTVA-TNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK 22971 Score = 160 bits (389), Expect = 3e-37 Identities = 192/881 (21%), Positives = 342/881 (38%), Gaps = 84/881 (9%) Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPK 1289 K V + E L + +II +C +Y+ + + T +V+V++ P Sbjct: 16782 KDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGP 16841 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSIDSKS 1342 D + SD+T ++ P+D+ +++ + I TK + D S Sbjct: 16842 PKDL-------KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGS 16894 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTILDK---PSPPGKPNILEIDSSS 1396 + + + + +++R EN G + T D P PP K I I ++ Sbjct: 16895 TTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT 16954 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTT-----EW--ISVKNITKTQTSIQNLKTNSSY 1449 +++ W P+N G S + +Y+VE D T W + +++ + Q ++++L Y Sbjct: 16955 VHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEY 17014 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGV 1508 FR AVN +S S T + P+++ LK + E ++ + GV Sbjct: 17015 EFRVKAVNAAGVSKPSATVGPCDC--QRPDMPPSID--LKEFMEVEEGTNVNIVAKIKGV 17070 Query: 1509 PQPKVTWYR------DGKK-----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 P P +TW++ D K+ K ++ Y A N+ G Sbjct: 17071 PFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLG 17130 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 + + +P + IK + D+ + PP + K N + + Sbjct: 17131 TASKEMRLNVLGRPGPPVG--PIKFESVSADQ----MTLSWFPPKDDGGSKITNYVIEKR 17184 Query: 1618 EYN------ITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKVYDKP 1666 E N ++++ K I +L H + I A N G S E ++ P Sbjct: 17185 EANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVP 17244 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE- 1724 P+ P + ++R S+T+ W+ P DGG +T Y +E + + RW +V D + + Sbjct: 17245 GAPDKPTV-SSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 17303 Query: 1725 --TYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 +Y + L E +Y FRV A N G A L S+P + + P Sbjct: 17304 GVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWT--K 17361 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFR 1838 S + W P K+GGS + Y VE K+EGK +W+ + + L Y+FR Sbjct: 17362 SSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFR 17421 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSP 1896 + A N G P D I + L P + V + ++ S P Sbjct: 17422 VSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP 17481 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + + +T+ ++ + + S+ I+N + + ++ + A+N G E + Sbjct: 17482 TVTWNMNERTLPQEATIETTAISSSM---VIKNCQRSHQGVYSLLAKNEAG-----ERKK 17533 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + VP P P + + +W +PE DGG+P+ Y I R+ + W V Sbjct: 17534 TIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPV 17593 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 V ++ L + Y RI A N IG+ +E+ E Sbjct: 17594 -TYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSE 17633 Score = 159 bits (386), Expect = 8e-37 Identities = 115/396 (29%), Positives = 184/396 (46%), Gaps = 15/396 (3%) Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 D P +PE VI +R +VT++WK P DGG ++T Y +EK + + RW+K + + Sbjct: 25531 DPPGRPEAIVI----TRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLE 25586 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVG-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDN 1781 + + L E+ Y FRVIA+N G FSE +S I + +D P+ I Sbjct: 25587 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 25646 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 + T+ G PI D V ++GK+ + + IQK ++ R Sbjct: 25647 HAGE-TFVLEADIRGKPIPD--VVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 25703 Query: 1842 RNEIG--TSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPIT 1898 I +++ T IT+ K L P P V+ T+ L W P +GG+ I+ Sbjct: 25704 GQYILKLSNVGGTKSIPITV-KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 25762 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 +YIIE + SWT++ T +++ + + + +E IFR+ A N G+ P ES V Sbjct: 25763 HYIIEKRETSRLSWTQVSTEVQALN-YKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 25821 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 P PP+ P E+ + + ++ +W P DGG + GY + RD W + K Sbjct: 25822 ACNPYKPPGPPSTP-EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 25880 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + L+ + L+E H+Y R+ A N G+ EP E Sbjct: 25881 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSE 25916 Score = 158 bits (384), Expect = 1e-36 Identities = 122/395 (30%), Positives = 175/395 (44%), Gaps = 18/395 (4%) Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 D P +PE ++ +R SVT++WK P DGG ++T Y +EK E RW+K A + Sbjct: 23367 DPPGRPEAIIV----TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK-ASFTNII 23421 Query: 1724 ETYC-IQKLNENCEYMFRVIAQNPVG-FSEALESE-PIVIKTALDVPSXXXXXXXXXXID 1780 +T+ + L E+ Y FRVIA+N G FSE ES I + +D P I Sbjct: 23422 DTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIV 23481 Query: 1781 NESVYITWFPSEKNGGS-PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839 + ++ G P I + IK + + LS+ R+ Sbjct: 23482 VHAGESFKVDADIYGKPIPTIQW---IKGDQELSNTARLEIKSTDFATSLSVKDAV--RV 23536 Query: 1840 YARNEIGTSLPYTSDDKITIG-KTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPI 1897 + N I + + +T+ K L P P V+S T+ TL W P +GGS I Sbjct: 23537 DSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDI 23596 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 NYI+E + WT +V + + E +E FRI A N GV P ES+ V Sbjct: 23597 INYIVERRETSRLVWT-VVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPV 23655 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + VP P AP E+ V + ++ W P DGG+ +LGY + RD W Sbjct: 23656 VAKNPFVVPDAPKAP-EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCH 23714 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 K + L+ + L ENH Y R+ A N GLSEP Sbjct: 23715 KRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 23749 Score = 158 bits (384), Expect = 1e-36 Identities = 113/414 (27%), Positives = 182/414 (43%), Gaps = 14/414 (3%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P KP+ P + + +R SV++ W P D+GG ++T Y IE + D + W K + Sbjct: 30960 PGKPQNPRVT-DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 31018 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXID-NES 1783 Y + L + EY FRV+A N G E E V + L+ P I + Sbjct: 31019 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 31078 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 I K PI + E + K+ I++ + + + N Sbjct: 31079 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 31138 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 + G Y K+ + + P P + + RSV + W P +GG+ I YI+E Sbjct: 31139 KCGKKAVYI---KVRVIGSPNSPEGPLEY--DDIQVRSVRVSWRPPADDGGADILGYILE 31193 Query: 1904 FKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEK 1961 + V +W I + V G+ ++ +KE E FR+SAEN G+S P +S+ V + Sbjct: 31194 RREVPKAAWYTIDSRVRGT--SLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 31251 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 P PP+ P E+ V + V SW P+ DGG+ + GY I ++ + W+ K + Sbjct: 31252 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 31311 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075 T + + L + Y RI A+N++GLSE + EP V+ + +PGE Sbjct: 31312 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEP--VVCKDPFDKPSQPGE 31363 Score = 156 bits (378), Expect = 7e-36 Identities = 106/368 (28%), Positives = 166/368 (45%), Gaps = 15/368 (4%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 +K+ S +R+++ R Y I+ N G + T+ V D P P + +I + S Sbjct: 15686 SKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN-FVFEDIRKTS 15744 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHE---PDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 V +W+PPLDDGG E+ Y +EK + PD+ WI V R + Y + KL E EY+F Sbjct: 15745 VLCKWEPPLDDGGSEIINYTLEKKDKTKPDSE-WIVVTSTLRHCK-YSVTKLIEGKEYLF 15802 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 RV A+N G S+P+V K P N S+ + W K+ GSPI Sbjct: 15803 RVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSN-SMLVKW-NEPKDNGSPI 15860 Query: 1800 IDYKVEIKQ-EGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 + Y +E ++ W A + L TY FR+ A N G D Sbjct: 15861 LGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDP 15920 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 T ++PP P V ++++S ++ L+W P NGG I Y ++ + V W++ Sbjct: 15921 KTAHDPISPPGPPIPRV-TDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCT 15979 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 V ++ ++ I+E + R+SA N G P E+Q V + A PP L++ Sbjct: 15980 EKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPAVELDVS 16036 Query: 1977 MVGSNIVM 1984 + G +M Sbjct: 16037 VKGGIQIM 16044 Score = 155 bits (377), Expect = 1e-35 Identities = 198/880 (22%), Positives = 337/880 (38%), Gaps = 48/880 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVV 1284 +TW K + D + S L + D +Y L ++ K + V+V+ Sbjct: 20652 ITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 20711 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P V+ + K + VT P ++V + ++ + + + S Sbjct: 20712 DTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTS 20771 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 + +E + +++ EN G D V P P + + SS +I W Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGW 20831 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 +P + G S II YVV++ + +W V Q S ++L Y FR A NE Sbjct: 20832 KKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGE 20890 Query: 1462 SDASETTEYYKVIKETKIQSPTVE-KPLKNI--TTEPNEDIELTCIFGGVPQPKVTWYRD 1518 SE T V+ + +P ++ K L ++ + N + L G P P V+W + Sbjct: 20891 GTPSEIT----VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 20946 Query: 1519 GKKLKT-AKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 L T + + E+ Y N G E + + + KP I Sbjct: 20947 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 21006 Query: 1575 IS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 D + +W G I K + N+K + + + R+ Sbjct: 21007 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS--VNNKWVTCASAVQKTTFRV 21064 Query: 1633 KELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 L + + A N G S V +D P P P I+ ++ +SV++ W Sbjct: 21065 TRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIV-DVRHDSVSLTW 21123 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 P GG +T Y +E E ++ W + + + + L E EY FRV+A N Sbjct: 21124 TDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLA 21183 Query: 1748 GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 G + +L SEP+V +D P I SV + W + +GG + Y VE Sbjct: 21184 GVGKPSLPSEPVVALDPIDPPG----KPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEK 21239 Query: 1807 KQ-EGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKT 1862 + K W + L Y+FRI A+N G S P S + I Sbjct: 21240 RDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDE 21299 Query: 1863 LTPPSQPRNFVVSES-TSRSVTLKWTEPESNGGSPI--TNYIIEFKTVKGKSWTKIVTVG 1919 P+ + + + T ++ S G P+ +++ K ++ T+I + Sbjct: 21300 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 21359 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 S I+ KD + I+A N G T+ + V++ VP PP P+EI V Sbjct: 21360 TS-SMLTIKYATRKDAGEYTITATNPFG----TKVEHVKVTV-LDVPGPP-GPVEISNVS 21412 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 + +W P DGG+P+ Y + R+ ++ +W V + D+ + + L + + Y+ Sbjct: 21413 AEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIF 21471 Query: 2040 RIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 R+ A N G EP++S EP K++ G E E + V Sbjct: 21472 RVSAVNHYGKGEPVQS-EPVKMVDRFGPPGPPEKPEVSNV 21510 Score = 155 bits (376), Expect = 1e-35 Identities = 180/814 (22%), Positives = 322/814 (39%), Gaps = 64/814 (7%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 K +D+ V + P +IV + +++ K T+ + +++ Sbjct: 15024 KNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFR 15083 Query: 1360 LRLENNCGHAD-VEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 + EN G +D E+ ++L K P PP ++++ +++ W+ P+N G I Sbjct: 15084 VAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQ 15143 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 YV+E +E T W+ + + ++ + +F+ A NE + SE TE Sbjct: 15144 RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEIL 15203 Query: 1472 KVIKETKIQSPTVEKPLKN-------ITTEPNEDIELTCIFGG----VPQPKVTWYR-DG 1519 + T SP ++ + + I +P E + I G P W R + Sbjct: 15204 SIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 15263 Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNE 1578 + +K K E I ++ E+ + V KP I + Sbjct: 15264 RPIKDLKFKVEE--GVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 15321 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 DI G++ + +P P V W+K+G +++ + ++ + + + R+ Sbjct: 15322 DIIVIE--GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA 15379 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 + YTI N G+++ + +KV P P + +I++ S + W+PP DGG + Sbjct: 15380 DAGIYTITLENKLGSATASINVKVIGLPG-PCKDIKASDITKSSCKLTWEPPEFDGGTPI 15438 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y +E+ E +I V + + ++ ++ L N EY FRV A N VG E +E + Sbjct: 15439 LHYVLERREAGRRTYIPVMSGENKL-SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP 15497 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWK--X 1815 VI P E++ ITW P +GGS I+ Y +E I + ++WK Sbjct: 15498 VIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCN 15557 Query: 1816 XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-V 1874 + L YQFR+ A N G S P + K + P P+ + Sbjct: 15558 EHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT---KAVDPIDAPKVILRT 15614 Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYI-----IEFKTVKGKSWTKIVTVGGSVHEH---- 1925 S R + S P +I I + +K ++ + G V E Sbjct: 15615 SLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFV 15674 Query: 1926 -------CIENIKE-KDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976 I+N K+ + ++ R S G+ + E+ + TV T I Sbjct: 15675 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 15734 Query: 1977 MVGSNI----VMTSWGTPEWDGGAPLLGYNIAIRDVTK--TMWMEVGKVDVNTLKFNIRD 2030 V +I V+ W P DGG+ ++ Y + +D TK + W+ V + K+++ Sbjct: 15735 FVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTST-LRHCKYSVTK 15793 Query: 2031 LSENHTYMIRIYARNEIG-----LSEPLESDEPF 2059 L E Y+ R+ A N G +S+PL + +PF Sbjct: 15794 LIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF 15827 Score = 153 bits (370), Expect = 7e-35 Identities = 116/432 (26%), Positives = 195/432 (45%), Gaps = 20/432 (4%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVTIEWK 1688 + + L+ ++ + A N G + Y P P G + R +T++W Sbjct: 24410 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 24469 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPV 1747 P+ DGG +T Y +EK + + RW+K A +ET + + L E+ Y FRVIA+N Sbjct: 24470 KPVYDGGSMITGYIVEKRDLPDGRWMK-ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAA 24528 Query: 1748 G-FSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS-PIIDYKV 1804 G S+ +S PI K +++P I + ++ +G P I++ Sbjct: 24529 GAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 24588 Query: 1805 EIKQEGKKWKXXXXXXXXXAR-IQKLSINTTY-QFRIYARNEIGT-SLPYTSDDKITIGK 1861 K+ + + A I K +I Q+ + A N G+ S P K Sbjct: 24589 GDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV-------K 24641 Query: 1862 TLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 L P P V V+ TS +L W+ P +GGS I++Y++E + +WT +V Sbjct: 24642 VLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWT-VVASEV 24700 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + + E +E +FRI A N GV P ES V ++ +P PP + LE+ + Sbjct: 24701 VTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKS-LEVTNIAK 24759 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + + W P+ DGG+ ++GY + RD + W++ K + L+ + L+E+H Y R Sbjct: 24760 DSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFR 24819 Query: 2041 IYARNEIGLSEP 2052 + A N G+ EP Sbjct: 24820 VSAENAAGVGEP 24831 Score = 151 bits (367), Expect = 2e-34 Identities = 176/756 (23%), Positives = 297/756 (39%), Gaps = 41/756 (5%) Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD-VGVIK 998 +EEG V L ++ WY K + + + +Q+ D G Sbjct: 4300 SEEGDIVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYV 4359 Query: 999 CIV-----KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERD 1052 C K ++ + VVK P RK++ EV +A EI S W + Sbjct: 4360 CEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKA 4419 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE-LPP 1107 G I + +K +I L I T V D GEY+C +E SCTA +TV E PP Sbjct: 4420 GREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 ++R ++ G A F +T G ++ W KDG+ + S + +++ K L++ Sbjct: 4479 TFLSRPKSLTTFVGKAAKFICTVT-GTPVIETIWQKDGAALSPSPNWKISDAENKHILEL 4537 Query: 1166 YDCDLDDAGEYSCEVGN----SKCTA-ILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 + + D G YSC+ N C A ++ +++P +F L E + N +L ++ Sbjct: 4538 SNLTIQDRGVYSCKASNKFGADICQAELIIIDKP--HFIKEL-EPVQSAINKKVHLECQV 4594 Query: 1221 -PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 D + VTW K + + + + + K TL I D Y C + ++ Sbjct: 4595 DEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSC 4654 Query: 1280 KVEV-VEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 V V PP V + Y + G L + P W N+K + + + Sbjct: 4655 SATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMY 4714 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 + A L I V+ D+G Y N+ G + I + PS +I + Sbjct: 4715 FVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTN 4774 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 + E TG I ++ + ++I + S K +Q S+ L+ + F + V Sbjct: 4775 ALLQCEVSGTGPFEISWF-KDKKQIRS----SKKYRLFSQKSLVCLEI---FSFNSADVG 4826 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 E + A+E + + + PT K + ++ + + L G VTW + Sbjct: 4827 EYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK 4886 Query: 1518 DGKKLK---TAKATYENRXXXXXX-XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 + ++ K ++ N Y C+A N+ G +TS I ++P Sbjct: 4887 GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEPAK 4945 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 I ++ Q GD + + G P + WYK+G L K+Y I+ K + ++ Sbjct: 4946 IIERAELIQV-TAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFY 5004 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + S +YT E SN G+SS E T V D+ P Sbjct: 5005 SAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 5040 Score = 150 bits (363), Expect = 5e-34 Identities = 198/893 (22%), Positives = 344/893 (38%), Gaps = 49/893 (5%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVK 1249 +E P I+ + + ++V A L + VTW +K I++ + + V Sbjct: 19528 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTW--RKVGIDNVVRKGQVDLVD 19585 Query: 1250 KRT-LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 L+I T DD +Y+ L++ + + V V++ P + D + K V+ Sbjct: 19586 TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVS 19645 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 +IV + + + + + K S + + + +++ N Sbjct: 19646 WAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEY 19705 Query: 1367 GHA---DVEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 G DV V D +P PP K + E+ +S + W P G + I Y+ Y+ Sbjct: 19706 GPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYR 19765 Query: 1421 EID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 E + W + + LK Y+FR A N V +S E Y+ KE + Sbjct: 19766 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA-KE-Q 19823 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXX 1534 + P + P + IT + + + + G P P W + ++ T+ A + ++ Sbjct: 19824 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 19882 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK--QKHKVGDEWLV 1592 Y A N G V + P DI W + Sbjct: 19883 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHI 19942 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 G I + + D + + KTS R+ +L + + A N G Sbjct: 19943 PLEDGGSNITNYI-VEKCDVSRGDWVTALASVTKTS-CRVGKLIPGQEYIFRVRAENRFG 20000 Query: 1653 TSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 S + K+ + PS+P+ + + ++++ + + W P DGG + Y IE+ E Sbjct: 20001 ISEPLTSPKMVAQFPFGVPSEPKNARVTK-VNKDCIFVAWDRPDSDGGSPIIGYLIERKE 20059 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 ++ W+K D Y L E EY FR+ A N G S S+P TA +P Sbjct: 20060 RNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSP--PSKPTEYVTA-RMP 20116 Query: 1768 SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARI 1826 + +V + W + +GGS II Y VE K G KW + Sbjct: 20117 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 20176 Query: 1827 Q----KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV-SESTSRS 1881 + L YQFR AR + S P D +TI PP + + S T ++ Sbjct: 20177 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 20236 Query: 1882 VTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 T + G P ++ + +K K + + ++ + ++ KD + I Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLCTLELFSVNRKDSGDYTI 20295 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +AEN+ G ++S +++L K P PP A ++I + S+ M SW P DGG+ + Sbjct: 20296 TAENSSG----SKSATIKL-KVLDKPGPP-ASVKINKMYSDRAMLSWEPPLEDGGSEITN 20349 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 Y + R+ ++ W +V V ++ L E H Y RI A N+ G+ +P+ Sbjct: 20350 YIVDKRETSRPNWAQV-SATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPV 20401 Score = 150 bits (363), Expect = 5e-34 Identities = 177/746 (23%), Positives = 296/746 (39%), Gaps = 54/746 (7%) Query: 1349 KVENTDAGI-YKLRL--ENNCGHADVEMN---VTILDKPSPPGKPNILEIDSSSINICWD 1402 K +N + GI Y+ R+ EN G N D PPG P + + + I + W Sbjct: 24410 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 24469 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 +P G S I Y+VE +++ W+ S N+ +TQ ++ L + Y FR A N Sbjct: 24470 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 24529 Query: 1461 -ISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 IS S++T E ++ +++ ++ I E L G P P + W R Sbjct: 24530 AISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRG 24589 Query: 1519 GKKLK-TAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 K+++ +A+ +N + Y A N G V + +P Sbjct: 24590 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPP 24649 Query: 1575 ISNEDIK--QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIR 1631 + K W G ++ Y + + + + E T+ ++ Sbjct: 24650 EGPVQVTGVTSEKCSLTWSPPLQDGG---SDISHYVVEKRETSRLAWTVVASEVVTNSLK 24706 Query: 1632 IKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEW 1687 + +L + + I A N G +E + P GP + + I+++S+T+ W Sbjct: 24707 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 24766 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 P DGG E+ Y +EK + RWIK + L E+ EY FRV A+N Sbjct: 24767 NRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAA 24826 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN--ESVYITWFPSEKNGGSPIIDYKVE 1805 G E S V A D +D S+ + W +GGS I+ Y VE Sbjct: 24827 GVGEP--SPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 24884 Query: 1806 I-KQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIG----TSLPYT--SDD 1855 I K + ++W+ I KL+ + Y+ R+ A N++G TS+P T +D Sbjct: 24885 ICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPED 24944 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 K+ + + VV S + + + G P I + +G+ K+ Sbjct: 24945 KLEAPELDLDSELRKGIVVRAGGSARIHIPFK------GRPTPE--ITWSREEGEFTDKV 24996 Query: 1916 -VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + G + + I+N D + + EN+ G ++S V + K P PP L Sbjct: 24997 QIEKGVNYTQLSIDNCDRNDAGKYILKLENSSG----SKSAFVTV-KVLDTPGPPQN-LA 25050 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 ++ V + W P DGGA + Y I R+ T+ + V T F + +L+E Sbjct: 25051 VKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKT-SFKVENLTEG 25109 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFK 2060 Y R+ A NE G+ P+E+ + K Sbjct: 25110 AIYYFRVMAENEFGVGVPVETVDAVK 25135 Score = 149 bits (362), Expect = 6e-34 Identities = 178/802 (22%), Positives = 301/802 (37%), Gaps = 60/802 (7%) Query: 1358 YKLRLENNCGHADVE--MNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +++ EN+ G + T+ P PPG P+ +++ +I + W+ P G S I+ Sbjct: 28756 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 28815 Query: 1415 YVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471 Y +E ++ W+ + ++++ Q ++ L Y FR A N V IS S+++ Sbjct: 28816 YSIEKRQ-GNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGI- 28873 Query: 1472 KVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG----KKLKT 1524 ++ + P VE + + + E + + + G P P+VTW++DG K++ Sbjct: 28874 -IMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 28932 Query: 1525 AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584 Y A N G + V +Q P + I+ + Sbjct: 28933 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVG--PIRFTN 28990 Query: 1585 KVGDE---WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 G++ W + +G P I + K E + ++K +K + + Sbjct: 28991 ITGEKMTLWWDAPLNDGCAP---ITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGN 29047 Query: 1642 KY--TIEASNTAGT----SSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 +Y + A N G S V ++ Y P P P I+ S+T+ W P DG Sbjct: 29048 EYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPE-PSNITGNSITLTWARPESDG 29106 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEAL 1753 G E+ +Y +E+ E + RW+KV ET + + L E EY F V+A+N G A Sbjct: 29107 GSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPAS 29166 Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKK 1812 ++ P +V + W +GG II Y +E+ K + Sbjct: 29167 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 29226 Query: 1813 WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ-- 1868 W R + L Y+FR+ A N G I LT P Sbjct: 29227 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDI 29286 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 NF + +++ + G P T + K S + S +E Sbjct: 29287 DANFKQTHVVRAGASIRLF--IAYQGRP-TPTAVWSKPDSNLSLRADIHTTDSFSTLTVE 29343 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSW 1987 N D + ++ EN G S+S+ K P PP P+ + V W Sbjct: 29344 NCNRNDAGKYTLTVENNSG------SKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMW 29396 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P DGGA + Y + R+ ++ W + + + F + DL+E Y R+ A NE Sbjct: 29397 DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQI-FKVNDLAEGVPYYFRVSAVNEY 29455 Query: 2048 GLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDADIRSY 2106 G+ EP E EP A E+P + WL+ +H+ + I Y Sbjct: 29456 GVGEPYEMPEPIV--------ATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGY 29507 Query: 2107 ARGSLLRRDEYFFRIWHYAKQL 2128 + +++ H KQL Sbjct: 29508 LLEMRQKGSDFWVEAGH-TKQL 29528 Score = 147 bits (355), Expect = 4e-33 Identities = 117/440 (26%), Positives = 189/440 (42%), Gaps = 28/440 (6%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEGPVIMREISRESVT 1684 ++ L H ++ I A N AG S+ T Y KP P P ++ + SR S++ Sbjct: 22642 KVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVL-DTSRSSIS 22700 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 I W P+ DGG E+T Y +E P+ + W I +Y I L EN EY R+ A Sbjct: 22701 IAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYA 22760 Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIID 1801 N G E AL + + P + + + F K +P + Sbjct: 22761 MNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVK 22820 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 + + + K + ++ + ++ + N G+ + + + Sbjct: 22821 WARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNV------R 22874 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 L P P++ V E T SVTL W P +GGS I NYI+E + K+++ TV + Sbjct: 22875 VLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS---TVATN 22931 Query: 1922 VHEHC--IENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978 H+ ++ ++E FR+ AEN G+ LP E ++SV+ + P PP + + V Sbjct: 22932 CHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASER---PLPP-GKITLMDV 22987 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 N V SW PE DGG+ +LGY + ++ W V V + I L + Y Sbjct: 22988 TRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVT--EATITGLIQGEEYS 23045 Query: 2039 IRIYARNEIGLSEPLESDEP 2058 R+ A+NE G+S+P + P Sbjct: 23046 FRVSAQNEKGISDPRQLSVP 23065 Score = 140 bits (338), Expect = 5e-31 Identities = 102/345 (29%), Positives = 149/345 (43%), Gaps = 14/345 (4%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 + + A N G ++A + IV+ LD P I ESV + W P + +GGS Sbjct: 27474 YEITAANSSGTTKAFIN--IVV---LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQ 27528 Query: 1799 IIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 + +Y + +K+E W + ++ KL+ YQFRI A N G S + Sbjct: 27529 VTNY-ILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGIS-DHIDSA 27586 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 +T+ T P P V+ T S+T+ W EP SNGGS + Y +E K W K Sbjct: 27587 CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 27646 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + + I FR+ AEN GV P+ L A P + I Sbjct: 27647 NKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC---EPPRNVRI 27703 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + N V SW P +DGG+ + GY + RD+ W + +V +F I L++N Sbjct: 27704 TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNS 27763 Query: 2036 TYMIRIYARNEIG-LSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 Y R++ARN +G +S P E P I G + P E TEV Sbjct: 27764 QYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEV 27808 Score = 137 bits (331), Expect = 4e-30 Identities = 196/790 (24%), Positives = 319/790 (40%), Gaps = 70/790 (8%) Query: 1214 AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL- 1271 A L+ +I L D+ WY+ + + K+ + SD + TL + ++D+ YTC+ Sbjct: 31477 AQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 31536 Query: 1272 ---DAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + ++++KL ++ +F P E+ Y GS + L V Y P P W K+ Sbjct: 31537 EVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWFHGQKL 31595 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVE-NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 ++ ++ L +K V+ T AG YK++L N G D ++V I DKP P Sbjct: 31596 LQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTG 31655 Query: 1387 PNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKN-ITKTQTSIQNL 1443 P ++E + +S I W P + G S I YVVE E + EW V + I+ T I NL Sbjct: 31656 PIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNL 31715 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 N+ Y FR A N ISD E + VI ++ + P P K T +D +C Sbjct: 31716 TENAGYYFRVSAQNTFGISDPLEVSSV--VIIKSPFEKPGA--PGKPTITAVTKD---SC 31768 Query: 1504 IFGGVPQ-----PKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIA 1552 + P K+ Y R+ K+ K T E Y + Sbjct: 31769 VVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKC 31828 Query: 1553 FNDHGEVETSCV-VGIQQKPVITISNEDIKQKHK---VGDEWLVTAV--IEGIPPPEVIW 1606 N GE E S + I K + I K++ + V + T V + G P P V W Sbjct: 31829 ENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKW 31888 Query: 1607 YKNGNKLEND-KEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSS------VEV 1658 Y+ G ++ D +Y I K + I + ++ Y + A+N G+ S VEV Sbjct: 31889 YRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 31948 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 K++ P EG + + E V+I K P + + + DNN +V Sbjct: 31949 PAKIH-LPKTLEGMGAVHALRGEVVSI--KIPFSGKPDPVITWQKGQDLIDNNGHYQVI- 32004 Query: 1719 VDRDVETYCIQKLNENCEYMFRVI-AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 V R + E + F V+ A+N G ++ + + + A DVP Sbjct: 32005 VTRSFTSLVFPNGVERKDAGFYVVCAKNRFG----IDQKTVELDVA-DVPD-PPRGVKVS 32058 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQ 1836 + +SV +TW +GGS I +Y VE ++W + L T+YQ Sbjct: 32059 DVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVINLFGKTSYQ 32118 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A N+ G S P + T+T + R E + + T+ + Sbjct: 32119 FRVIAENKFGLSKPSEPSE-----PTITKEDKTRAMNYDEEVDETREVSMTKASHSSTKE 32173 Query: 1897 I-TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 + Y+I +G+ G VH C+E +K + + + T V + E Sbjct: 32174 LYEKYMIAEDLGRGEF--------GIVH-RCVETSSKKTYMAKFVKVKGTDQVLVKKEIS 32224 Query: 1956 SVRLEKHATV 1965 + + +H + Sbjct: 32225 ILNIARHRNI 32234 Score = 134 bits (323), Expect = 3e-29 Identities = 205/920 (22%), Positives = 361/920 (39%), Gaps = 86/920 (9%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 KKPK E + + E + P + W K EI P + + E +H L + Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVSERKVHK----LML 2853 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 N+ G YT V E +A L + E + + +K++ V + ++ + Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFV---------ETLHITKTMKNIEVPETKTASFECE 2904 Query: 758 VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V P++ W KN ++ G H + I+ +D YT N + Sbjct: 2905 VSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTS-TEDSAEYTFVCGNDQ--- 2959 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 SA +TV P + + ++I +EK TI V + S W +N I Sbjct: 2960 -VSATLTVT--------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIK 3009 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 ++ L I NV D+ DY VA GK++ A + ++ + F KH+ Sbjct: 3010 STDKCQMRTKKLTHSLNIRNVHFG-DAADYTFVA----GKATSTATLYVEARHIEFRKHI 3064 Query: 935 QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 K + E K + EC+ S ++ +W + +E+ D +I +E D Sbjct: 3065 -KDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSD 3123 Query: 994 VGVIKCIVKDQETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVVWERD 1052 G +V ST + E IR ++ + +V EK A++E E+N + D W +D Sbjct: 3124 AGKYT-VVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKD 3182 Query: 1053 GEIIK---PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPE 1108 G I +++KY E+R H +++I T D GEY+ + R+ S PP+ Sbjct: 3183 GIEINFQVQERHKYVVERRIH--RMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQ 3240 Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 ++ LQ V G A F ++ + + W+K+ + + DG++ L + + Sbjct: 3241 VLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE 3300 Query: 1168 CDLDDAGEYSCEVGN----SKCTAILTVEEPSI-NFTLRLPEF---ILVPANTD------ 1213 +DA Y+CE N + +A L+VE P + + +P + I+ P Sbjct: 3301 AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ 3360 Query: 1214 -AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 A + L V+WY K I+ + F + L I + +D+ YT V + Sbjct: 3361 PARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN 3420 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI-IKKC 1331 A + P+ + +E RI++ ++ + +F +E + ++++ + K Sbjct: 3421 AVGQVSSTANLSLEAPESILHE---RIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKI 3477 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAG-IYKLRLEN-NCGHADV-EMNVTILDKPSPPGK-- 1386 T + T E G I+ + N + DV ++VT++ P P + Sbjct: 3478 NETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWF 3537 Query: 1387 -PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 +L S+ +D + +S II + E + T ++ + KT S LK Sbjct: 3538 FNGVLLTPSADYKFVFDGDD---HSLIILFTKLEDEGEYT-CMASNDYGKTICSAY-LKI 3592 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 NS E ++ + E K P K LK I Sbjct: 3593 NSKGEGHKDTETESAVAKSLE--------KLGGPCPPHFLKELKPIRCAQGLPAIFEYTV 3644 Query: 1506 GGVPQPKVTWYRDGKKLKTA 1525 G P P VTW+++ K+L T+ Sbjct: 3645 VGEPAPTVTWFKENKQLCTS 3664 Score = 133 bits (321), Expect = 6e-29 Identities = 118/411 (28%), Positives = 171/411 (41%), Gaps = 31/411 (7%) Query: 1666 PSKPEGPVIMREIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P KP GP E+S ++S+ + W P+DDGG E+ Y +EK + + RW K Sbjct: 25825 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 25884 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXXXXXXXXXXID 1780 + L E Y FRV A+N G E SEP V A D P Sbjct: 25885 DLRLRVTGLTEGHSYEFRVAAENAAGVGEP--SEPSVFYRACDALYPPGPPSNPKVTDTS 25942 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR---IQKLSINTTYQ 1836 SV + W +GG+P+ Y VE+K+ +W + + KL NT Y Sbjct: 25943 RSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 26002 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPP-----SQPRNFVVSESTSRSVTLKWTEPES 1891 FRI A N G P T + + + PP + R VV + S TL+ Sbjct: 26003 FRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA---SATLRLFVTIK 26059 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 P ++++ +G + + V S I+N+ D + ++ EN G Sbjct: 26060 GRPEP----EVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSK- 26114 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 T +VR+ PS P L IR V + V SW P DGGA + Y + R+ T+ Sbjct: 26115 -TAFVNVRV---LDSPSAP-VNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTR 26169 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + + T F I +L E +Y R+ A NE G+ P E+ EP KV Sbjct: 26170 KAYATITNNCTKT-TFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 26219 Score = 130 bits (313), Expect = 5e-28 Identities = 142/602 (23%), Positives = 246/602 (40%), Gaps = 42/602 (6%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E P+F + L P +G VQ C V+G +I W + IKPS D + Sbjct: 9267 KEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPS-DRCSFSFAS 9325 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 A L +R+V D+G + C A N AG S TT+ S++T+ Sbjct: 9326 GTAVLELRDVAKADSGDYVCKASNVAG--SDTTK-----------SKVTIKDKPAVAPAT 9372 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 A + +G F +P++ V E + ++ P P++ W KG+ ++ V Sbjct: 9373 KKAAV-DG-RLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT-KGKWRQLNQGGRVF 9429 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 I + L+I + K G Y VA N GE + L++ +K+ ++ L++ Sbjct: 9430 IHQKGDE--AKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQ-EKIEGDLRA 9486 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKP----KKVK 798 M+ + ++ + KN P + + G T +L+ K+ + Sbjct: 9487 MLKK--TPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQ 9544 Query: 799 DEGVYTLKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIKLV 853 +E + L+ E E E +++ + EP I + TV K+ + + Sbjct: 9545 EEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEI 9604 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P ++WY+ E + PS+ + DG+ L + N + D G+Y+ V Sbjct: 9605 DIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLK-DQGNYRLVC----- 9658 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDH 972 H A + V + + +HLQ +EG+T + CQ S V ++W+ N + + Sbjct: 9659 -GPHIASAKLTVIEPAWERHLQ-DVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGR 9716 Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKD 1032 + E + D G C +D ETS L ++ +F +++Q+ V E Sbjct: 9717 HKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQ 9776 Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 A E E++ + A V W + G + KY+F G + I N + DEG YS I R Sbjct: 9777 SATFECEVSFDDAIVTWYK-GPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIAR 9835 Query: 1093 DE 1094 E Sbjct: 9836 LE 9837 Score = 129 bits (311), Expect = 9e-28 Identities = 112/445 (25%), Positives = 188/445 (42%), Gaps = 29/445 (6%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--VYDKPSKPEGPVI---MREISRESVT 1684 ++++ L H ++ ++A N G + + V P +P GP + + ++ S+T Sbjct: 19382 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSIT 19441 Query: 1685 IEWKPPLDDGGLELTKYAIEKH------EPDNNRWIKVADVDRDV-ETYCIQKLNENCEY 1737 + W P+ DGG + Y +E PD W + + V + + + L+EN EY Sbjct: 19442 LGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCNAAAQLVRKEFTVTSLDENQEY 19500 Query: 1738 MFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXX-IDNESVYITWFPSEKNG 1795 FRV AQN VG E E I K L+ P I I F + Sbjct: 19501 EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR 19560 Query: 1796 GSPIIDY-KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 +P + + KV I +K + I + + + ++ + N G + + Sbjct: 19561 PAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNV 19620 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 + L P + VS+ T S + W PE++GGS +T+YI+E + K+W+ Sbjct: 19621 ------RVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWST 19674 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPL 1973 + H + N+ +E FR++A N G +PT+ + V + P PP L Sbjct: 19675 VTPEVKKTSFH-VTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPP-RKL 19732 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK--TMWMEVGKVDVNTLKFNIRDL 2031 E+ + N +W P DGGA + GY + R+ + W E V L + L Sbjct: 19733 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSV--VKDLSLVVTGL 19790 Query: 2032 SENHTYMIRIYARNEIGLSEPLESD 2056 E Y R+ ARN +G+S P E++ Sbjct: 19791 KEGKKYKFRVAARNAVGVSLPREAE 19815 Score = 125 bits (302), Expect = 1e-26 Identities = 86/303 (28%), Positives = 131/303 (43%), Gaps = 7/303 (2%) Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812 +S PI +K LD P + E Y+ W P ++GG+ I Y +E ++ + Sbjct: 25717 KSIPITVKV-LDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 25775 Query: 1813 W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 W + ++ KL Y FR+ A N+ G P S +T PP P Sbjct: 25776 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGP-VTACNPYKPPGPPST 25834 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 VS T S+ + W P +GG+ I YI+E + +G WTK + + + Sbjct: 25835 PEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 25894 Query: 1932 EKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 E FR++AEN GV P+E S R P PP+ P ++ + V +W P Sbjct: 25895 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP-KVTDTSRSSVSLAWSKP 25953 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 +DGGAP+ GY + +++ W + +F + L EN Y RI A N G+ Sbjct: 25954 IYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGV 26013 Query: 2050 SEP 2052 EP Sbjct: 26014 GEP 26016 Score = 124 bits (300), Expect = 2e-26 Identities = 90/303 (29%), Positives = 135/303 (44%), Gaps = 11/303 (3%) Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815 PI + T L PS I +SV ++W E NGG I Y +E ++ + WK Sbjct: 28575 PITVIT-LGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKM 28633 Query: 1816 XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFV 1873 ++ L + YQFR+ A N G S P S I + K P P V Sbjct: 28634 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSS--IIVAKHQFRIPGPPGKPV 28691 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 + TS ++L W P +GGS +T + +E K W K+ T S E+ + E Sbjct: 28692 IYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEG 28751 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 + FR+ AEN+ G+S P++ L + PP P I + I + W P D Sbjct: 28752 LDYQFRVYAENSAGLSSPSDPSKFTLA--VSPVDPPGTPDYIDVTRETITL-KWNPPLRD 28808 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEP 2052 GG+ ++GY+I R + W+ DV+ ++ + LS Y RI ARN +G +S P Sbjct: 28809 GGSKIVGYSIEKRQGNER-WVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPP 28867 Query: 2053 LES 2055 +S Sbjct: 28868 SQS 28870 Score = 124 bits (299), Expect = 3e-26 Identities = 159/709 (22%), Positives = 282/709 (39%), Gaps = 39/709 (5%) Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 VK QE L+ KE P L D +E D+ L I + +V W + +++ P Sbjct: 4274 VKIQEAEGGLI-KEDGPMIHTPLVDTVSEEGDIVHLTTSITN-AKEVNWYFENKLV-PSD 4330 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHD-EGEYSC-ILRDESCTA---EVTVVELPPEIITR-LQ 1114 K+ + + L I + D +GEY C L D TA ++TVV+ +I R ++ Sbjct: 4331 EKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIE 4390 Query: 1115 NQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 +V G+ A F E+ + +WFK G EI S+ + L+I + D Sbjct: 4391 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 4450 Query: 1174 GEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLDVT 1228 GEY+C E G+ CTA LTV E L P+ + A ++ ++ Sbjct: 4451 GEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETI 4510 Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEF 1286 W K + + + + + K L + T D+ Y+C + + E +++ Sbjct: 4511 WQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 4570 Query: 1287 PPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P I + E + I + + VD + W + + + K K + K A+L Sbjct: 4571 PHFIKELEPVQSAINKKVHLECQVDEDR--KVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDSSSINI-CWD 1402 I + D+G Y N G + VT+ + PS K P+ L + S + C Sbjct: 4629 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKL 4688 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 + T E E +T V + + I ++K S + AVN D+ Sbjct: 4689 KGSPVIQVTWFKNNKELSESNTVRMYFVNS--EAILDITDVKVEDSGSYSCEAVN--DVG 4744 Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 S +TE VIKE P+ K L+ + L C G +++W++D K++ Sbjct: 4745 SDSCSTEI--VIKEP----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI 4798 Query: 1523 KTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 +++K + ++ Y+C+ N+ G+ +++ P + Sbjct: 4799 RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVD 4858 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 D+ G + A + G P V W K + D + ++ +V+ I +++ S Sbjct: 4859 DLIALG--GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQIS 4916 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 KYT A N AG+ + L V + E +++ + + T+E+ Sbjct: 4917 FGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 4965 Score = 124 bits (298), Expect = 4e-26 Identities = 123/454 (27%), Positives = 188/454 (41%), Gaps = 34/454 (7%) Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 T+ ++ L ++ ++A N G S + L V + + P I +S TI+ Sbjct: 16278 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP-PTIKLRLSVRGDTIK 16336 Query: 1687 WKP------PLDDGGLELTKYAIEKHE-----PDNNRWIKVADVDR-DVET-YCIQKLNE 1733 K P D GL + K K+E P + I +V R + +T I K Sbjct: 16337 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 16396 Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 + + V A N +G + + + D PS I ES Y+TW Sbjct: 16397 EDKGTYTVTASNRLG--SVFRNVHVEV---YDRPSPPRNLAVTD-IKAESCYLTWDAPLD 16450 Query: 1794 NGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSL 1849 NGGS I Y ++ + +K W+ I KL N Y+FR+ A N+ G S Sbjct: 16451 NGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISD 16510 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 SD K+ I P P V T S+ + WT P NGGSPIT Y +E + Sbjct: 16511 ECKSD-KVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGS 16569 Query: 1910 KSWTK-----IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 W++ I VG E + + E + FR A N G+ P+E + Sbjct: 16570 PYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPI 16629 Query: 1965 VP-SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD--V 2021 P PP+ P E++ + + W P DGG+P+ GY + +++ T W V + D + Sbjct: 16630 FPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLI 16688 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 T + + +L E Y R+ A NE G SEP ++ Sbjct: 16689 TTCECVVPNLKELRKYRFRVKAVNEAGESEPSDT 16722 Score = 123 bits (297), Expect = 5e-26 Identities = 83/293 (28%), Positives = 131/293 (44%), Gaps = 15/293 (5%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXX-XARIQKLSINTTY 1835 + ++ + W P E +GG I +Y +E K E K+ W + +L Y Sbjct: 19235 VSSDRCTVCWDPPEDDGGCEIQNYILE-KCETKRMVWSTYSATVLTPGTTVTRLIEGNEY 19293 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 FR+ A N+IGT P ++ K I KT P +P V++ + +T+ W PE +GG Sbjct: 19294 IFRVRAENKIGTGPP--TESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGG 19351 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-E 1953 IT Y +E K W + ++N+ E FR+ AEN +G+ P+ Sbjct: 19352 KSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLP 19411 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S+ V + P PPT + +I + WG P +DGGAP++GY + +R Sbjct: 19412 SRPVVAKDPIEPPGPPTNFRVVDTTKHSITL-GWGKPVYDGGAPIIGYVVEMRPKIADAS 19470 Query: 2014 MEVGKVDVNTL------KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + G N +F + L EN Y R+ A+N++G+ P E E K Sbjct: 19471 PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 19523 Score = 123 bits (296), Expect = 6e-26 Identities = 145/607 (23%), Positives = 241/607 (39%), Gaps = 44/607 (7%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXX----XXXXXYKCIAF 1553 + L ++ G P P +TW+ K L+ ++ T EN YK Sbjct: 31573 LRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLS 31632 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV--IWYKNG- 1610 N G V+ V IQ KP I+ K +AVI PP + W N Sbjct: 31633 NVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN------SAVISWKPPADDGGSWITNYV 31686 Query: 1611 -NKLENDK--EYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTL 1660 K E + E+ + + + RI L + + + A NT G SSV + Sbjct: 31687 VEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIK 31746 Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720 ++KP P P I ++++S + WKPP DGG ++ Y +EK E N+WI V + Sbjct: 31747 SPFEKPGAPGKPTITA-VTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEE 31805 Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXI 1779 + ++ L E EY FRV +N G SE E SEPI K+ + + + Sbjct: 31806 IRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLN 31865 Query: 1780 DNESVYITWFPSEKNGGSPIIDYK---VEIKQEGKKWKXXXXXXXXXARI-QKLSINTTY 1835 T PI+ + EI +G K++ I ++ + Sbjct: 31866 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 31925 Query: 1836 QFRIYARNEIGTSLPYTSDDKITI-GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 +++ A N+ G S+ T+ ++ + K P + V V++K P S Sbjct: 31926 VYQVRATNQ-GGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKI--PFSGKP 31982 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 P+ + + +++ ++ KD + + A+N G+ + Sbjct: 31983 DPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGI----DQ 32038 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 ++V L+ A VP PP +++ V + V +W P DGG+ + Y + T W+ Sbjct: 32039 KTVELDV-ADVPDPPRG-VKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWL 32096 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP--FKVIPGEGSHADEE 2072 VG+ ++ + +L +Y R+ A N+ GLS+P E EP K + DEE Sbjct: 32097 RVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEE 32154 Query: 2073 PGEQTEV 2079 E EV Sbjct: 32155 VDETREV 32161 Score = 120 bits (288), Expect = 6e-25 Identities = 88/313 (28%), Positives = 139/313 (44%), Gaps = 10/313 (3%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXX 1822 LD P + E + W P ++GGS II+Y VE ++ + W Sbjct: 23561 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 23620 Query: 1823 XA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + ++ KL Y FRI A N+ G P S+ + + P + P+ V+ T S Sbjct: 23621 LSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDA-PKAPEVTTVTKDS 23679 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRI 1940 + + W P S+GGS I Y++E + +G WT+ + G + + + E + FR+ Sbjct: 23680 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLR-VTGLIENHDYEFRV 23738 Query: 1941 SAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 SAEN G+S P+ + + P PP P I + S++ + SW P +DGG + Sbjct: 23739 SAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFL-SWSKPIYDGGCEIQ 23797 Query: 2000 GYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 GY + DV+ W M +N + L E H Y RI A N+ G+ E +D P Sbjct: 23798 GYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGE--HADVP 23855 Query: 2059 FKVIPGEGSHADE 2071 +I E A + Sbjct: 23856 GPIIVEEKLEAPD 23868 Score = 115 bits (276), Expect = 2e-23 Identities = 109/456 (23%), Positives = 179/456 (39%), Gaps = 28/456 (6%) Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 EY++ V +KE K+ K+ + A N G S VY+ + P I+ Sbjct: 19776 EYSVVKDLSLVVTGLKEGKKY---KFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP 19832 Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 E +TI+ L + + K P +W K D + K + + Sbjct: 19833 ---EQITIKAGKKL-----RIEAHVYGKPHP-TCKWKKGEDEVVTSSHLAVHKADSSSIL 19883 Query: 1738 MFRVIAQNPVGF-------SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 + + + + G+ S +++ I + +D P ID ++ ++W Sbjct: 19884 IIKDVTRKDSGYYSLTAENSSGTDTQKIKV-VVMDAPGPPQPPFDISDIDADACSLSWHI 19942 Query: 1791 SEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTS 1848 ++GGS I +Y VE + W + R+ KL Y FR+ A N G S Sbjct: 19943 PLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGIS 20002 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 P TS K+ PS+P+N V++ + + W P+S+GGSPI Y+IE K Sbjct: 20003 EPLTSP-KMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERN 20061 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 W K E+ + E E FRI A N G S P++ A +P Sbjct: 20062 SLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT---ARMPVD 20118 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV--DVNTLKF 2026 P E+ V + V W P+ DGG+ ++GY + + W+ + ++ Sbjct: 20119 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 20178 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 L E Y R AR + +S P E +P ++ Sbjct: 20179 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTIL 20214 Score = 107 bits (258), Expect = 3e-21 Identities = 105/448 (23%), Positives = 177/448 (39%), Gaps = 41/448 (9%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P V L+ +G +V EC + GYP P +TW+R+ I+ S DFQ+ + +A L+ Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLM 1001 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXXXXXXXXAD 627 IRE F ED+G FTC A N AG S++ L V+ + +T D Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061 Query: 628 IL--------------EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 ++ E P F KP Q + EG ++ C++ P+P + W G Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121 Query: 674 IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 + V+ V+ +T G YT+V N+ GE S L E + Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFAD--DAGEYTIVVRNKHGETSASASL---LEEAD 1176 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 +++ + M+ + + + VG P + + K + T++ Sbjct: 1177 YELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVV 1236 Query: 794 PKKVKDEGVYTLKAENS--EGIAETSAVITVEEPTEENAEPPLFIN-------------R 838 V+D+ + E + I T+EE EE+ E + ++ R Sbjct: 1237 RTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLR 1296 Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIELVITNVD 896 + + E + +++ P+P I WY++ + I E +F DG L I V Sbjct: 1297 IKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIPVVL 1355 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTID 924 E D G Y ASN G + ++ ++ Sbjct: 1356 PE-DEGIYTAFASNIKGNAICSGKLYVE 1382 Score = 107 bits (258), Expect = 3e-21 Identities = 77/283 (27%), Positives = 123/283 (43%), Gaps = 11/283 (3%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXA-RIQKLSINTT 1834 I SV W P +GGS II+Y +E K + K +W + KL Sbjct: 15740 IRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKE 15799 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y FR+ A N G P S + PP P +V + TS S+ +KW EP+ NG Sbjct: 15800 YLFRVRAENRFGPGPPCVSKPLVA-KDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNG- 15857 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 SPI Y +E + V W+++ + + ++ + E +FR+ AEN G P + Sbjct: 15858 SPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAG---PGKF 15914 Query: 1955 QSVRLEKHATVP-SPPTAPL-EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 K A P SPP P+ + S + W P ++GG ++GY + + V Sbjct: 15915 SPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNE 15974 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 W + + ++ ++++ E Y +R+ A N G P E+ Sbjct: 15975 WSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGET 16017 Score = 107 bits (258), Expect = 3e-21 Identities = 80/287 (27%), Positives = 127/287 (44%), Gaps = 12/287 (4%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQ 1836 + ES ++W + GG+ I +Y VE ++ G W+ ++ L+ Y Sbjct: 29680 VSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYS 29739 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ + N G S P S I PPS P V ++ +++++W EP +GGS Sbjct: 29740 FRVSSENRFGVSKPLESAP-IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSK 29798 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955 I Y +E K W K V + + + E E FR A N GVS +E S+ Sbjct: 29799 IIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASR 29858 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT---M 2012 + + P P E+ V + V W P +DGG+ ++GY I + V++ Sbjct: 29859 PIMAQNPVDAPGRP----EVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGR 29914 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG-LSEPLESDEP 2058 W++ V+ F + LSE TY R+ A+N G +S+ ES P Sbjct: 29915 WLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGP 29961 Score = 107 bits (256), Expect = 4e-21 Identities = 116/515 (22%), Positives = 208/515 (40%), Gaps = 31/515 (6%) Query: 1554 NDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY--KN 1609 NDHG + C V + P I EDI+ K V +W + +G E+I Y + Sbjct: 15712 NDHGIAKAPCTVSVLDTPGPPINFVFEDIR-KTSVLCKW-EPPLDDG--GSEIINYTLEK 15767 Query: 1610 GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLKVY 1663 +K + D E+ + T + + +L + + A N G S V + Sbjct: 15768 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF 15827 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 P P+ P++ +++ S+ ++W P D+G + Y +EK E ++ W +V + Sbjct: 15828 GPPDAPDKPIV-EDVTSNSMLVKWNEPKDNGS-PILGYWLEKREVNSTHWSRVNKSLLNA 15885 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNE 1782 + L E Y+FRV A+N G + S P KTA D + + Sbjct: 15886 LKANVDGLLEGLTYVFRVCAENAAGPGKF--SPPSDPKTAHDPISPPGPPIPRVTDTSST 15943 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRI 1839 ++ + W P NGG I+ Y V+ + G +W + ++++ Y+ R+ Sbjct: 15944 TIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRV 16003 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N G P +T+ + PP+ + V P G P+ Sbjct: 16004 SAVNAAGEG-PPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPT 16062 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 + + + ++ G+ E I++ KD + I+A N+ G ++ + R+ Sbjct: 16063 KVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG----SKFAAARV 16118 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 E VP P L+ + + + +W PE DGG+ + G+ I +D W + + Sbjct: 16119 EVF-DVPG-PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ--PI 16174 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + K +I L E Y R+ A+N+ G P+E Sbjct: 16175 ETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVE 16209 Score = 104 bits (249), Expect = 3e-20 Identities = 81/313 (25%), Positives = 140/313 (44%), Gaps = 19/313 (6%) Query: 523 DGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G V++ C++E Y + Q+TW+ ++ S+ +++ Y+D VA L ++++ D GT+ Sbjct: 32508 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGTY 32566 Query: 582 TCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 C N G SS EL V+ + D+ T+ +LE PP F+ Sbjct: 32567 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMR---LLER-PPEFTLP 32622 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKIT 698 + G ++ + PEP + W G++I P D + ESD +Y L I Sbjct: 32623 LYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY--QLTIN 32680 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-----RQGESVI 753 +V + YTVVA N+ GE S L + + P+ ++ ++G+SV Sbjct: 32681 SVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVC 32740 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENS 810 +V G P PT+ W K+ +P+ P +G + ++ +D G Y + A N+ Sbjct: 32741 FEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNT 32800 Query: 811 EGIAETSAVITVE 823 G A + VE Sbjct: 32801 AGSTSCQAHLQVE 32813 Score = 104 bits (249), Expect = 3e-20 Identities = 172/833 (20%), Positives = 327/833 (39%), Gaps = 71/833 (8%) Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK 795 +++ +SM V +GES S G P PT+TW + + + T + + Sbjct: 33489 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 33548 Query: 796 KVK--DEGVYTLKAENSEGIAETSAVITVEEP--TEENAEPPLFINRFQEITVKEKGTIK 851 V+ DEG Y++ ENSEG E +T+++ TE+ P + + E VK +K Sbjct: 33549 SVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV-KSPEPRVKSPEAVK 33607 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 RV ++P PS + + +SP+ET + E ++ + + +I K AS Sbjct: 33608 SPKRV-KSPEPS-----HPKAVSPTET--KPTPTEKVQHLPVSAPPKITQF-LKAEASKE 33658 Query: 912 AGKSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM 970 K + ++ ++VT+ K +K E + T K + + G Sbjct: 33659 IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ---FHYSADGTYELKINNLTESDQGE 33715 Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK-------DQETSTMLVVKETIPE----- 1018 EI EG + + + K DQ+T+ V ++T P+ Sbjct: 33716 YVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI 33775 Query: 1019 -----FIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGEII-KPKKNKYDFEKRGHI 1071 + LQD V VA V+ E +W +DG+ I + K K +K G Sbjct: 33776 SSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFF 33835 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131 L I T D G Y+C +++ + + + +L + I + QKV+ + T EI Sbjct: 33836 --LEIHKTDTSDSGLYTCTVKNSAGSVSSSC-KLTIKAIKDTEAQKVS--TQKTSEITPQ 33890 Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY--SCEVGNSKCTAI- 1188 K A+V+ ++ S I+++ ++KL + + +A + S EV S T++ Sbjct: 33891 K-KAVVQEEISQKALR-SEEIKMSEAKSQEKLALKE----EASKVLISEEVKKSAATSLE 33944 Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE------------TLDVTWYKKKSVI 1236 ++ I T + E + A A+ T +E DV W + Sbjct: 33945 KSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVEL 34004 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-----VEFPPKIV 1291 ++E++ +TL I++ + D+ TC+ + K + ++ + P + Sbjct: 34005 TNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFI 34064 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 R I G +V + P P EW N+ I + S SL I+ Sbjct: 34065 SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 34124 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +D+G Y ++ +N G ++ +L P + +L S ++ + + Sbjct: 34125 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR-TSGDTSLQGSFSSQSVQMS 34183 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 + ++ S+ + S Q++ + + + + IS+ ++ Sbjct: 34184 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESST 34243 Query: 1472 KVIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + + I+ P +E +I+ + + + + C F G P P+VTW G+K+ Sbjct: 34244 SKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKI 34296 Score = 99 bits (238), Expect = 7e-19 Identities = 108/439 (24%), Positives = 183/439 (41%), Gaps = 33/439 (7%) Query: 1044 TADVVWERD-GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT--AEV 1100 T ++ W R+ GE +K EK + +L I N +D G+Y L + S + A V Sbjct: 24980 TPEITWSREEGEFT----DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 25035 Query: 1101 TVVELP-PEIITRLQNQKVNKGNK-ATFEIELTKGDALVR-WFKDGSEIQFSNHIQLTID 1157 TV L P L ++V K + +E + G A V+ + D E + ++ Sbjct: 25036 TVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSK 25095 Query: 1158 GKKQKLK--------IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 K K IY + E+ V A+ E PS + L + Sbjct: 25096 CSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDV---- 25151 Query: 1210 ANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 + T A L E P D V Y + + TEK++++++ K ++ + + ++ Sbjct: 25152 SQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFR 25211 Query: 1268 CVLLDAKSTTKLKVEVVEFPPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDE 1320 + K + +V V K + + Y I+ G D+ + + P+PN Sbjct: 25212 VKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNIS 25271 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W+ + + +K+ + S L IK+ D G Y + N+ G A ++V +L+K Sbjct: 25272 WVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 25331 Query: 1381 PSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT 1438 P PP G E+ + + I W+ P TG I Y+VE ++ TT W V + +T Sbjct: 25332 PGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI 25391 Query: 1439 SIQNLKTNSSYRFRAYAVN 1457 I LKT + Y+FR +A N Sbjct: 25392 KITKLKTGTEYQFRIFAEN 25410 Score = 95.5 bits (227), Expect = 1e-17 Identities = 60/204 (29%), Positives = 102/204 (50%), Gaps = 10/204 (4%) Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 ++R ++ I K+ +GE P + + +K + + GE+ LS Q+VG P P I W + Sbjct: 31440 LSRPRRTAMSIKTKLTSGEA--PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFG 31497 Query: 773 KPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 K + + SDG TH++T++ ++ +DEGVYT A N G ETS+ + ++ + + Sbjct: 31498 KELIQSRKYKMSSDGRTHTLTVMTEEQ-EDEGVYTCIATNEVGEVETSSKLLLQATPQFH 31556 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 PL + + T++L PVP++TW+ +++ SE IT Sbjct: 31557 PGYPLKEKYYGAVG----STLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTH 31612 Query: 890 LVITNVDSEIDSGDYKCVASNSAG 913 LV+ NV + +G YK SN G Sbjct: 31613 LVMKNVQRKTHAGKYKVQLSNVFG 31636 Score = 91.5 bits (217), Expect = 2e-16 Identities = 61/201 (30%), Positives = 103/201 (51%), Gaps = 13/201 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LP----TKSDGDT 786 + P +PL+S++V +G + A + G P P ++W ++ + + LP + SDG Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 +TI K + G Y+LKA N G A ++A + V+ T PP F+ R Q +TV++ Sbjct: 64 -KLTIPAVTKA-NSGRYSLKATNGSGQATSTAELLVKAETA----PPNFVQRLQSMTVRQ 117 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 ++L RVT P P + +YR+ I S + +G+ L+I E DSG Y Sbjct: 118 GSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPE-DSGTYSV 176 Query: 907 VASNSAGKSSHGARVTIDVEK 927 A+NS G+++ A + + E+ Sbjct: 177 NATNSVGRATSTAELLVQGEE 197 Score = 91.5 bits (217), Expect = 2e-16 Identities = 58/201 (28%), Positives = 101/201 (50%), Gaps = 13/201 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTH 787 +P V++P+ S +G++ +VVG P P W + + + + K DG T Sbjct: 1456 KPVFVLKPV-SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG-TQ 1513 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 S+ I+ P D G +T+ A+N G + S ++TVE E+ P+F+ + + + +KE Sbjct: 1514 SLIIV-PATPSDSGEWTVVAQNRAGRSSISVILTVE--AVEHQVKPMFVEKLKNVNIKEG 1570 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI--DSGDYK 905 +++ R T NP P I W +N++II P + +G E + +DS + DS Y Sbjct: 1571 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAAL-KIDSTVSQDSAWYT 1629 Query: 906 CVASNSAGKSSHGARVTIDVE 926 A N AG+ + +V ++VE Sbjct: 1630 ATAINKAGRDTTRCKVNVEVE 1650 Score = 89.0 bits (211), Expect = 1e-15 Identities = 54/175 (30%), Positives = 80/175 (45%), Gaps = 9/175 (5%) Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK----CKHTKPSIDSKSAS--LTIKKVE 1351 ++K G V + D P P EW N +I+K + TK + A L+I K Sbjct: 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G Y + N G ++V + D+PSPP + +I + S + WD P + G S Sbjct: 16396 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSE 16455 Query: 1412 IIYYVVEYQEID--TTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 I +YV++ ++ EW V N + + I L N Y FR AVN+ ISD Sbjct: 16456 ITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISD 16510 Score = 88.2 bits (209), Expect = 2e-15 Identities = 61/202 (30%), Positives = 99/202 (49%), Gaps = 9/202 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 PTF++ ++ V EGS E + P P+++W G+ I V I SD Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR--- 62 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L I V K G Y++ A N G+A+ L +K E PP ++ L+SM VRQG V Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA-ETAPPNFVQRLQSMTVRQGSQV 121 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L +V G P P + + ++ +++ +GD +S+ I + +D G Y++ A N Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP-EDSGTYSVNATN 180 Query: 810 SEGIAETSAVITVEEPTEENAE 831 S G A ++A + V+ E A+ Sbjct: 181 SVGRATSTAELLVQGEEEVPAK 202 Score = 87.0 bits (206), Expect = 5e-15 Identities = 109/506 (21%), Positives = 193/506 (38%), Gaps = 39/506 (7%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 ++ +A L D G+ + + + L + P K V E +++ C Sbjct: 13536 VVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE- 13589 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 V W F+ EE + D + + ++ D+ +Y L+I + + Y V N G Sbjct: 13590 VNTEGAKAKW-FRNEEAIFDSSKYIILQKDL-VY--TLRIRDAHLDDQANYNVSLTNHRG 13645 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775 E I E+E +++EPLK + + +SV + V T+ W KN + V Sbjct: 13646 ENVKSAANLIV--EEEDLRIVEPLKDIETMEKKSVTFWCK-VNRLNVTLKWTKNGEEVPF 13702 Query: 776 -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 + + D H +TI K DEG Y + A + +AE ++ +E PTE Sbjct: 13703 DNRVSYRVDKYKHMLTI-KDCGFPDEGEYIVTAGQDKSVAE---LLIIEAPTE------- 13751 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 F+ ++ TV E +++R ++ WYRN I + DG L+I + Sbjct: 13752 FVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 13810 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 + D +Y C + + AR+ ++ V ++ Q E V L Sbjct: 13811 CRLD-DECEYACGVEDRKSR----ARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKD 13865 Query: 955 TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014 V +W N + D +++ EG+ D G + I KD+E L + Sbjct: 13866 KVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLEL-A 13924 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 P+ QD V + V ++ A+ W ++ E + K + Sbjct: 13925 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK----TIDTTAEQTS 13980 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAE 1099 I D+G Y +L+++ AE Sbjct: 13981 FRILEAKKGDKGRYKIVLQNKHGKAE 14006 Score = 86.2 bits (204), Expect = 9e-15 Identities = 61/211 (28%), Positives = 94/211 (44%), Gaps = 9/211 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F KP + EG + ++V P P+ W G++IV D V I+ D Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESV 752 ++ T G +TVVA NR G +S+ ++L ++ E + P +E LK++ +++G + Sbjct: 1517 IVPAT---PSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQL 1573 Query: 753 ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAE 808 + + GNP P I W KN+ P K + +G + V +D YT A Sbjct: 1574 EMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAI 1633 Query: 809 NSEGIAETSAVITVE-EPTEENAEPPLFINR 838 N G T + VE E E E L I R Sbjct: 1634 NKAGRDTTRCKVNVEVEFAEPEPERKLIIPR 1664 Score = 84.6 bits (200), Expect = 3e-14 Identities = 70/270 (25%), Positives = 116/270 (42%), Gaps = 25/270 (9%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +++L+P G +F + G P+P+I+W+++ ++ + +D TL+ Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY-TLL 3297 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP-LSDHGSEMTVXXXXXXXXXXXXADI 628 + E FPEDA +TC AKN G A+++ L VE P + EM V Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV--------------- 3342 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 PP + EG +CR V+ + ++W K ++I P + D Sbjct: 3343 ---YPPAIITPLQDTVTSEGQPARFQCR-VSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT 3398 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L+I EGTYT VA N G+ S L ++ E + IE M +++ Sbjct: 3399 YQ----LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKE 3454 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKAL 778 S LSA+ G + K N+ ++ L Sbjct: 3455 FSSSFLSAEEEGLHSAELQLSKINETLELL 3484 Score = 83.0 bits (196), Expect = 8e-14 Identities = 51/198 (25%), Positives = 92/198 (46%), Gaps = 3/198 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ G +V L + Y+ P+P+ W+ + +K+ + + S +L+IK + G Y Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 28561 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + L+N V + V L PS P P EI + S+ + WD PE+ G I Y + Sbjct: 28562 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 28621 Query: 1418 EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 E +E T W V ++ +T + NL ++ Y+FR A N +S + + Sbjct: 28622 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPL-VSSIIVAKHQ 28680 Query: 1477 TKIQSPTVEKPLKNITTE 1494 +I P + + N+T++ Sbjct: 28681 FRIPGPPGKPVIYNVTSD 28698 Score = 81.8 bits (193), Expect = 2e-13 Identities = 149/701 (21%), Positives = 260/701 (37%), Gaps = 54/701 (7%) Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 KP++ V EG C P P + WL KG+ + V Y S +I+ Sbjct: 33493 KPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK----YKSTFEIS 33548 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 +V+ EG Y+VV N EG+ L I+ V P + V+ E + S + Sbjct: 33549 SVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPR---VKSPEPRVKSPEA 33605 Query: 759 VGNPR----PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V +P+ P + K P + PT ++ H + + P K+ LKAE S+ IA Sbjct: 33606 VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH-LPVSAPPKI----TQFLKAEASKEIA 33660 Query: 815 E-----TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARVTRNPVPSITWYR 868 + S+V+ +E T L N + GT +L + +T + Sbjct: 33661 KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI 33720 Query: 869 NNEIISPSETITQNFDGENIELVITNVD--SEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + E S+T Q F G+ + + V SE D K S K+ A I Sbjct: 33721 SGE-GGTSKTNLQ-FMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPIS-S 33777 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYHNKKEISGMDHREIIQEGRXXXXX 985 K V LQ + + + T T W + K I+ ++ ++ Sbjct: 33778 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE 33837 Query: 986 XXXXXXXDVGVIKCIVKDQETS-------TMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 D G+ C VK+ S T+ +K+T + + + E+ + A+++ Sbjct: 33838 IHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQE 33897 Query: 1039 EINSETADVVWERDGEI-IKPKKNKYDFEKRGHIRKLYIR---NTSVHDEGEYSCILRDE 1094 EI+ + R EI + K++ + K+ I S E S + + Sbjct: 33898 EISQKAL-----RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 33952 Query: 1095 SCTAEVT-VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 + T++ + V EI +N+G + + + G V+W +G E+ S + Sbjct: 33953 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIA-GATDVKWVLNGVELTNSEEYR 34011 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV--EEPSINFTLRLPEFIL 1207 + G Q L I D G +C + G KC LT+ E + P Sbjct: 34012 YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQN 34071 Query: 1208 VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + + T EI E + ++ W+K I + ++ +L IR + D +Y Sbjct: 34072 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 34131 Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 T + + ++ P + + RE ++ D +L Sbjct: 34132 TIKAKNFRGQCSATASLMVL-PLVEEPSREVVLRTSGDTSL 34171 Score = 81.0 bits (191), Expect = 3e-13 Identities = 65/245 (26%), Positives = 104/245 (42%), Gaps = 31/245 (12%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E+ P+FV K +G T +F+ +V G P P+ WF I ++ +D Sbjct: 1452 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1511 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 +L+I P D+G +T VA+N AG +S + L VEA Sbjct: 1512 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA---------------------- 1549 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 + + P F +K K + EGS + ++ R P PDI WL + IVP + + I Sbjct: 1550 ---VEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRI 1606 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E + LKI + YT A+N+ G + + ++ EP EP + + Sbjct: 1607 EGTKGE--AALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP----EPERKL 1660 Query: 745 IVRQG 749 I+ +G Sbjct: 1661 IIPRG 1665 Score = 79.4 bits (187), Expect = 1e-12 Identities = 94/421 (22%), Positives = 165/421 (39%), Gaps = 35/421 (8%) Query: 1074 LYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEIITR-LQNQKVNKGNKAT-FE 1127 + I+N +G YS + ++E+ T V V+++P + T L + N+ K T F Sbjct: 17507 MVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFS 17566 Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 E G + + + E +T +Q + L Y + Sbjct: 17567 PEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQG--LIQGKAYFFRIAAENSIG 17624 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW-------------YKKKS 1234 + E S +R P I VP + E+ T+ +TW Y +S Sbjct: 17625 MGPFVETSEALVIREP--ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES 17682 Query: 1235 VIEDTEKFTLISD--VKKRTLIIRKCTEDDQCEYTCVLLDAKS-------TTKLKVEVVE 1285 + TEKF +++ + R ++ E D EY ++ T + + Sbjct: 17683 RLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDEL 17742 Query: 1286 FPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 PP + +D+ + I+ G L Y P+P W + + + T + + Sbjct: 17743 APPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLA 17802 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDE 1403 L K + +D+G Y + +EN+ G V ++D+P PP G + E+ + I W Sbjct: 17803 LEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKP 17862 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 P + G S I Y++E +E+ W+ V + + KT + L Y FR +A N IS Sbjct: 17863 PLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGIS 17922 Query: 1463 D 1463 D Sbjct: 17923 D 17923 Score = 78.6 bits (185), Expect = 2e-12 Identities = 49/187 (26%), Positives = 78/187 (41%), Gaps = 6/187 (3%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--SASLTIKKVENTDAG 1356 +K G + L + P P W + + + ID++ S+ ++ K + +D G Sbjct: 19140 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 19199 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y + N G V +LDKP P I+++ S +CWD PE+ G I Y+ Sbjct: 19200 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYI 19259 Query: 1417 VEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 +E E W + T T++ L + Y FR A N++ TE VI Sbjct: 19260 LEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKI---GTGPPTESKPVIA 19316 Query: 1476 ETKIQSP 1482 +TK P Sbjct: 19317 KTKYDKP 19323 Score = 77.0 bits (181), Expect = 5e-12 Identities = 124/586 (21%), Positives = 227/586 (38%), Gaps = 62/586 (10%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 +K K V E EC + P + WL G EI E + ++ +H L Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ----LI 2939 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 I N YT V N + A+L + P + LK + + +++ Sbjct: 2940 IMNTSTEDSAEYTFVCGNDQVSATLTVT---------PIMITSMLKDINAEEKDTITFEV 2990 Query: 757 QVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 V + W KN +K+ ++ THS+ I + D YT A G Sbjct: 2991 -TVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNI-RNVHFGDAADYTFVA----GK 3044 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A ++A + VE E F ++I V EK V+ P ++ W ++++ + Sbjct: 3045 ATSTATLYVEARHIE------FRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQEL 3097 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 ++ I + L+I + D+G Y VA + A++ ++ V ++ Sbjct: 3098 QITDRIKIQKEKYVHRLLIPSTRMS-DAGKYTVVAGGNVST----AKLFVEGRDVR-IRS 3151 Query: 934 LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXX 990 ++K + E + ++E + + V WY + EI+ + + + E R Sbjct: 3152 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3211 Query: 991 XXDVGVIKCIV-KDQETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVV 1048 D G + +++ + T+ V P+ +++LQ V+ K V + Sbjct: 3212 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEVTV 1102 W ++ +++ K F G L + D Y+C +++ S + V V Sbjct: 3272 WYKEEQLLSTGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330 Query: 1103 VEL----------PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152 E+ PP IIT LQ+ ++G A F+ ++ D V W+ +I+ S Sbjct: 3331 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFF 3390 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEP 1194 ++T +L+I + +D G Y S VG TA L++E P Sbjct: 3391 RMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436 Score = 76.2 bits (179), Expect = 9e-12 Identities = 64/231 (27%), Positives = 104/231 (45%), Gaps = 35/231 (15%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ--DFQMYYDDDN 564 + AP F + L+ +GST FE + G+P P+++WFR +I S Q+ + D Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 A L I V ++G ++ A N +G A+ST +E+ V Sbjct: 63 -AKLTIPAVTKANSGRYSLKATNGSGQATST-------------AELLVKA--------- 99 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 E PP F ++ ++ V +GS + L+ R+ IP P + + G EI + ++ Sbjct: 100 -----ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQ 154 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735 E D++ L I GTY+V A N G A+ L ++ GE+E P Sbjct: 155 EGDLYS----LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ-GEEEVP 200 Score = 76.2 bits (179), Expect = 9e-12 Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 9/212 (4%) Query: 1288 PKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 P IV++ EY IK G + + Q P P W + I+K + + + S Sbjct: 28882 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28941 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWD 1402 SL ++ G+Y + +N G A E+ V + D P G I + + WD Sbjct: 28942 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 29001 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVD 1460 P N G + I +Y++E +E W +++ + Q T+I+ + N Y+FR AVN+ Sbjct: 29002 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGN-EYQFRVSAVNKFG 29060 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 + ++ I+ T +P + +P NIT Sbjct: 29061 VGRPLDSDPVVAQIQYTVPDAPGIPEP-SNIT 29091 Score = 73.7 bits (173), Expect = 5e-11 Identities = 41/112 (36%), Positives = 60/112 (53%), Gaps = 2/112 (1%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 ++P P E P + L+ T +G +F+C+V G +++W+ + IKPS Sbjct: 3329 EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPS 3387 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + F+M +D L I E +PED GT+T VA NA G SST L +EAP S Sbjct: 3388 RFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3438 Score = 73.3 bits (172), Expect = 7e-11 Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 13/205 (6%) Query: 476 DENNYTQYLQ-KKLNEKIDKL---PVFE-KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFE 530 +E ++ LQ K+NE ++ L PV+ K SE++ PIF++++ G Sbjct: 3464 EEGLHSAELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3523 Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 V G P+P+I WF ++ PS D++ +D D+ +L+I ED G +TC+A N G Sbjct: 3524 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD-HSLIILFTKLEDEGEYTCMASNDYG 3582 Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG-IPPTFSKKPKAQYVDEGS 649 + L + + H T + L G PP F K+ K +G Sbjct: 3583 KTICSAYLKINSKGEGHKDTET------ESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 3636 Query: 650 DILLECRLVAIPEPDIAWLFKGEEI 674 + E +V P P + W + +++ Sbjct: 3637 PAIFEYTVVGEPAPTVTWFKENKQL 3661 Score = 72.9 bits (171), Expect = 9e-11 Identities = 80/324 (24%), Positives = 121/324 (37%), Gaps = 30/324 (9%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 DEG+ + V + E + E I IE +M + S + Sbjct: 3410 DEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHS 3469 Query: 706 GTYTVVAVNREGE--ASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGN 761 + +N E + P+ EKE P I+ + + + G+ LS V+G Sbjct: 3470 AELQLSKINETLELLSESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGI 3529 Query: 762 PRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P+P I W N P DGD HS+ IL K ++DEG YT A N G SA Sbjct: 3530 PKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTK-LEDEGEYTCMASNDYGKTICSA 3588 Query: 819 VITVEEPTEENAE------------------PPLFINRFQEITVKEKGTIKLVARVTRNP 860 + + E + + PP F+ + I + V P Sbjct: 3589 YLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEP 3648 Query: 861 VPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P++TW++ N+ + S TI N +G I N DSG Y C A N G+S+ Sbjct: 3649 APTVTWFKENKQLCTSVYYTIIHNPNGSG--TFIVNDPQREDSGLYICKAENMLGESTCA 3706 Query: 919 ARVTIDVEKVTFVKHLQKSYETEE 942 A + + +E K+ T E Sbjct: 3707 AELLVLLEDTDMTDTPCKAKSTPE 3730 Score = 72.9 bits (171), Expect = 9e-11 Identities = 64/217 (29%), Positives = 88/217 (40%), Gaps = 28/217 (12%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 EG P F K+ + G L ++ IP+P I W F G + P + + D H Sbjct: 3499 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3558 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT---GEKE------------- 733 L I K EG YT +A N G+ LKI + G K+ Sbjct: 3559 S----LIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3614 Query: 734 -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT 786 PP ++ LK + QG I VVG P PT+TW K NK + T Sbjct: 3615 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3674 Query: 787 HSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 S T I+ + +D G+Y KAEN G + +A + V Sbjct: 3675 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3711 Score = 72.5 bits (170), Expect = 1e-10 Identities = 36/96 (37%), Positives = 61/96 (63%), Gaps = 1/96 (1%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++ P FV++L+ GS V+ + +V G P P + ++R A I+ S DFQ+ + D + Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD-L 158 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +L+I E +PED+GT++ A N+ G A+ST EL+V+ Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194 Score = 72.1 bits (169), Expect = 2e-10 Identities = 64/298 (21%), Positives = 122/298 (40%), Gaps = 11/298 (3%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTL 1244 TA VE P I+ + + I+V A L ++ + L + W + IE++ + + Sbjct: 24542 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 24601 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKR 1301 + K LI++ D +Y + + + V+V++ P P + Sbjct: 24602 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 24661 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 +T Q ++V + + T + + + SL + K+ + ++++ Sbjct: 24662 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 24721 Query: 1362 LENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 N G + + +L K P PP + I S+ +CW+ P++ G S II Y+ Sbjct: 24722 AVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 24781 Query: 1417 VEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 VE ++ WI + + IT + + L + Y FR A N + + S T YYK Sbjct: 24782 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYK 24839 Score = 71.7 bits (168), Expect = 2e-10 Identities = 72/330 (21%), Positives = 133/330 (40%), Gaps = 40/330 (12%) Query: 646 DEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 +EG + C++ + + W F ++ E + E + ++L + ++ K Sbjct: 32507 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGV----AILYVKDITKLD 32562 Query: 705 EGTYTVVAVNREGEASLPIVLKIK------------TGEK------------EPPQVIEP 740 +GTY VN GE S L +K T +K PP+ P Sbjct: 32563 DGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLP 32622 Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALPTKSDGDTHSITILKP 794 L + GE+V + +P P +TW K+ + + K +SD + +TI Sbjct: 32623 LYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI-NS 32681 Query: 795 KKVKDEGVYTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 D+ YT+ A N E + +T+ P ++ P+F +E ++ Sbjct: 32682 VTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCF 32741 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 RV+ P P++ W ++ + +S I +G + + D+G Y+ A+N+A Sbjct: 32742 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTA 32801 Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 G +S + + VE++ + K KS E E Sbjct: 32802 GSTS--CQAHLQVERLRYKKQEFKSKEEHE 32829 Score = 69.3 bits (162), Expect = 1e-09 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRP-KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P FV+KL K G ++Q EC++ G P +++WFR + + S + M + + +VA L Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFIN-SVALL 7349 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I E ED+G + C A N G AS +T L V+AP Sbjct: 7350 TINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 7384 Score = 69.3 bits (162), Expect = 1e-09 Identities = 54/172 (31%), Positives = 90/172 (52%), Gaps = 16/172 (9%) Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---P 734 E S+ ES + C+ + +T + QE + V A N +G++ P VL + K+ Sbjct: 25184 EKWSIVAESKV---CNAV-VTGLSSGQEYQFRVKAYNEKGKSD-PRVLGVPVIAKDLTIQ 25238 Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P + P + ++ GE + + V+G PRP I+W K+ +P+K + +T + T+L Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 25298 Query: 795 KK-VKDE-GVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEIT 843 K+ KD+ G YT+ A NS G A E +VI +E+P PP+ RF E++ Sbjct: 25299 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP-----GPPVGPVRFDEVS 25345 Score = 68.5 bits (160), Expect = 2e-09 Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 12/163 (7%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-----TIKKVENTDAGIYKLRLENNCGHA 1369 P+ + + + I++KC+ + + SA++ T+ ++ + I+++R EN G Sbjct: 19247 PEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 19306 Query: 1370 DVEMNVTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + ++ DKP P P + ++ + + W+ PE G +I Y +E +E + Sbjct: 19307 PPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 19366 Query: 1425 TEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 T W+ V I + + +QNL + Y+FR A NE+ I + S Sbjct: 19367 TRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPS 19409 Score = 68.5 bits (160), Expect = 2e-09 Identities = 75/299 (25%), Positives = 130/299 (43%), Gaps = 15/299 (5%) Query: 319 EAAKVKKQVF--VPPKLPDVEKTELEQPLFSYEDIVESK-KDENEIIQEKQTLEELPKED 375 EA KV Q + P+ V + E+ Q E+I S+ K + ++ +++ + L E+ Sbjct: 33875 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEE 33934 Query: 376 VPEQYTITPRKSSAQKIDEIVDEVTIKKRLNP-FEIFYTPVEVRCGDTVFAVYSYVAETD 434 V + + KS + + + + R + + F T + + G + + TD Sbjct: 33935 VKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD 33994 Query: 435 EAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDK 494 ++ G L T+++++ Y + A + DE T K E I K Sbjct: 33995 VKW-VLNGVEL----TNSEEYRYGVSGSDQTLTIKQASH-RDEGILTCI--SKTKEGIVK 34046 Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 ++ S+E S AP F+ + R ++ +G V F C++ G P P+I WF+ I S Sbjct: 34047 CQ-YDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISS 34105 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 + + NV +L IR D+G +T AKN G S+T L+V PL + S V Sbjct: 34106 NVSI-SRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-LPLVEEPSREVV 34162 Score = 67.3 bits (157), Expect = 4e-09 Identities = 69/297 (23%), Positives = 126/297 (42%), Gaps = 18/297 (6%) Query: 1187 AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI 1245 A+ T E P I ++L + V A T L + + +TW K +++ ++ T+ Sbjct: 14608 AVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE 14667 Query: 1246 SDVKKRTLIIRKCTEDDQCEYT--CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 + KK T+ I D Y V + ++T ++V V++ P ++ I + Sbjct: 14668 NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFD----ITDVT 14723 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSIDSKSASLTIKKVENTDAGIYK 1359 + + L+ + I N + ++ + K S K + K+ I++ Sbjct: 14724 NESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFR 14783 Query: 1360 LRLENNCGHAD-VEMN-VTILDKPSPPGKPNILE---IDSSSINICWDEPENTGNSTIIY 1414 + EN G + V+ + +T + PPG P LE I ++ + W EP++ G S I Sbjct: 14784 VAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITG 14843 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 Y VE + DT +W+ + T+ ++ L YRFR A N S++TE Sbjct: 14844 YWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTE 14900 Score = 67.3 bits (157), Expect = 4e-09 Identities = 62/257 (24%), Positives = 110/257 (42%), Gaps = 16/257 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 ++W K ++++E K TL I+ ++ +YT +L +A + + V+ Sbjct: 28522 ISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITL 28581 Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSIDSKSA 1343 PP + + V L D P+ N + I+K T + S Sbjct: 28582 GPPSKPKGPIRFDEIKADSVILSWD---VPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 28638 Query: 1344 SLTIKKVEN--TDAGI-YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSS 1395 + T KV N DA +++R EN G + ++ I+ K P PPGKP I + S Sbjct: 28639 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 28698 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRA 1453 +++ WD P G S + + VE +E ++ W ++ I+ + L Y+FR Sbjct: 28699 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 28758 Query: 1454 YAVNEVDISDASETTEY 1470 YA N +S S+ +++ Sbjct: 28759 YAENSAGLSSPSDPSKF 28775 Score = 66.1 bits (154), Expect = 1e-08 Identities = 37/104 (35%), Positives = 56/104 (53%), Gaps = 2/104 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 SE +++ F +++ +G V F C++ GYP P+I W++ IK + +QM + Sbjct: 1284 SESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ 1343 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APL 604 D A+L I V PED G +T A N G A + +L VE APL Sbjct: 1344 DGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPL 1387 Score = 65.7 bits (153), Expect = 1e-08 Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 9/185 (4%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNK-YDFEKRGHIRKL 1074 P F + LQ V E A E I+ +V W RDG++I KL Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65 Query: 1075 YIRNTSVHDEGEYSCILRDES----CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEI 1128 I + + G YS + S TAE+ V PP + RLQ+ V +G++ ++ Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQV 125 Query: 1129 ELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 +T +V++++DG+EIQ S Q++ +G L I + +D+G YS NS A Sbjct: 126 RVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRA 185 Query: 1188 ILTVE 1192 T E Sbjct: 186 TSTAE 190 Score = 64.9 bits (151), Expect = 2e-08 Identities = 64/281 (22%), Positives = 114/281 (40%), Gaps = 14/281 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P I R+++ +V G F + + +K A V+W+ +G E+Q S+ I T L+I Sbjct: 33301 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 33360 Query: 1166 YDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPE--FILVPANTDAYLTVEIP 1221 DC DD+G Y N K A T++ ++T + VP + LT Sbjct: 33361 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELT---R 33417 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS----T 1276 E V+ +KK S +E + + S + + + E L+ KS + Sbjct: 33418 TEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKS 33477 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 T K++ +I+ R + G D P P W+ +++ + Sbjct: 33478 TTRKIKTT-LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQV 33536 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + ++ I V+ +D G Y + +EN+ G + E +TI Sbjct: 33537 TTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 33577 Score = 64.9 bits (151), Expect = 2e-08 Identities = 80/400 (20%), Positives = 138/400 (34%), Gaps = 13/400 (3%) Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 E + P IV ++ + S V P+P W + K I + K S D Sbjct: 33773 EPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKG 33832 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSPPGKPNILEIDSSSINIC 1400 L I K + +D+G+Y ++N+ G +TI K + K + + + Sbjct: 33833 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKK 33892 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE-- 1458 E + ++ E + E +++K + +K +++ V+E Sbjct: 33893 AVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEI 33952 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 S ASE + IK Q E + ++ + GV YR Sbjct: 33953 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 34012 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITIS 1576 G T + CI+ G V+ + + ++ Sbjct: 34013 GVSGSDQTLTIKQASHRDEGILT--------CISKTKEGIVKCQYDLTLSKELSDAPAFI 34064 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 ++ Q G L T I G P PE+ W+KN + +I+ + I+ Sbjct: 34065 SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 34124 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 S S KYTI+A N G S +L V +P V++R Sbjct: 34125 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLR 34164 Score = 64.9 bits (151), Expect = 2e-08 Identities = 84/402 (20%), Positives = 149/402 (37%), Gaps = 60/402 (14%) Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + W + S++++ Y + TL I++ D G TC++K G +L + Sbjct: 33995 VKWVLNGVELTNSEEYR-YGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 34053 Query: 601 EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAI 660 LSD P F +P++Q ++EG ++L C + Sbjct: 34054 SKELSD--------------------------APAFISQPRSQNINEGQNVLFTCEISGE 34087 Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P P+I W I N+S++ +++ L+I N G YT+ A N G+ S Sbjct: 34088 PSPEIEWFKNNLPISISSNVSISRSRNVYS----LEIRNASVSDSGKYTIKAKNFRGQCS 34143 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780 L + P V EP + +++R L G+ +K + + Sbjct: 34144 ATASLMVL------PLVEEPSREVVLRTSGDTSLQ----GSFSSQSVQMSASKQEASFSS 34193 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAE----NSEGIAETSAVITVEEPTEENAE----- 831 S S+T +K + + + +++ +S S + +E T + + Sbjct: 34194 FSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRG 34253 Query: 832 -PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE- 889 PP +I++ E + + T P P +TW I E F EN + Sbjct: 34254 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQE--QGRFHIENTDD 34311 Query: 890 ---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 L+I +V + D G Y N G S A V I + + Sbjct: 34312 LTTLIIMDVQKQ-DGGLYTLSLGNEFGSDS--ATVNIHIRSI 34350 Score = 63.7 bits (148), Expect = 5e-08 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Query: 495 LPVFEKPTSE-EQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 +P F+ E SM AP E+++ + GS F +V G P P+ W++ I+ Sbjct: 2061 IPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIER 2120 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 S Y+ +DNV LVIR+V ED+ + A N AG SS L+V+A Sbjct: 2121 SDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170 Score = 62.9 bits (146), Expect = 9e-08 Identities = 62/302 (20%), Positives = 121/302 (40%), Gaps = 13/302 (4%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV 1284 V+W+K ++ +++ T+ +D L + K D YT L + +T + V+V+ Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P D + K +T P +++ + + + S Sbjct: 15405 GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS 15464 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL--DKPSPPGKPNILEIDS---SSIN 1398 T+K + ++++ N G + +E+ ++ D PP P +E+ + ++ Sbjct: 15465 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMT 15524 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQT-SIQNLKTNSSYRFRAYAV 1456 I W P G S I+ Y++E W +++ T + + L+ Y+FR A Sbjct: 15525 ITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAE 15584 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N IS+ S T K + I +P V ++ + ++I L G P P +TW Sbjct: 15585 NAAGISEPSRATPPTKAV--DPIDAPKVIL-RTSLEVKRGDEIALDASISGSPYPTITWI 15641 Query: 1517 RD 1518 +D Sbjct: 15642 KD 15643 Score = 61.3 bits (142), Expect = 3e-07 Identities = 82/345 (23%), Positives = 146/345 (42%), Gaps = 28/345 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F ++ + V S+ L C++ P+P + W +G+EI+ D + I+ Y Sbjct: 31855 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIAD-GLKYRIQEFKGGYHQ 31913 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752 ++ I +V Y V A N+ G S L+++ K P+ +E + ++ +GE V Sbjct: 31914 LI-IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 31972 Query: 753 ILSAQVVGNPRPTITWCK------NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + G P P ITW K NN + + T+S S+ + KD G Y + Sbjct: 31973 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRS---FTSLVFPNGVERKDAGFYVVC 32029 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSIT 865 A+N GI + TVE + +PP R +++ + ++ L + IT Sbjct: 32030 AKNRFGIDQK----TVELDVADVPDPP----RGVKVSDVSRDSVNLTWTEPASDGGSKIT 32081 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTI 923 Y + + +E + + N+ + S ++ +A N G K S + TI Sbjct: 32082 NYIVEKCATTAERWLRVGQARETRYTVINLFGK-TSYQFRVIAENKFGLSKPSEPSEPTI 32140 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 E T + + E +E + V + + SH+ STK + K I+ Sbjct: 32141 TKEDKT--RAMNYDEEVDETREVSM-TKASHS-STKELYEKYMIA 32181 Score = 60.9 bits (141), Expect = 4e-07 Identities = 60/267 (22%), Positives = 107/267 (40%), Gaps = 14/267 (5%) Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 + ++I + ++WYK +E ++KF + D + TL ++ C DQ Y V Sbjct: 9604 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC--GPH 9661 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 K+ V+E P + ++ +K G T+ + P EW N +I+K K Sbjct: 9662 IASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHK 9718 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDS 1394 ++ K LTI V D G Y C + D+E + + + P I I Sbjct: 9719 TEVEHKVHKLTIADVRAEDQGQY------TCKYEDLETSAELRIEAEPIQFTKRIQNIVV 9772 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRA 1453 S E E + + I+ + E+ ++ + +N + +I N+ + + Sbjct: 9773 SEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSV 9832 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQ 1480 A E +A T E Y KE K++ Sbjct: 9833 IARLE-PRGEARSTAELYLTTKEIKLE 9858 Score = 60.9 bits (141), Expect = 4e-07 Identities = 60/235 (25%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP ++++ T G Q CQ+ G P P I W+R + S+ ++M D TL Sbjct: 31459 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTL 31517 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 + ED G +TC+A N G ++++L+++A H Sbjct: 31518 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFH--------------------- 31556 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 P + K K Y GS + L + P P + W F G++++ + ++ IE+ Sbjct: 31557 -----PGYPLKEK-YYGAVGSTLRLHVMYIGRPVPAMTW-FHGQKLLQNSE-NITIENTE 31608 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPL 741 H V+K +K G Y V N G +A L + ++ K + P VIE L Sbjct: 31609 HYTHLVMKNVQ-RKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL 31662 Score = 60.5 bits (140), Expect = 5e-07 Identities = 48/209 (22%), Positives = 84/209 (40%), Gaps = 10/209 (4%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + G P K+ K G L C++V P PDI W G+E++ ++ + Sbjct: 31454 LTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR 31513 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV- 746 H L + ++ EG YT +A N GE L ++ + P PLK Sbjct: 31514 TH----TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY--PLKEKYYG 31567 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVY 803 G ++ L +G P P +TW K ++ + +T T L K V+ + G Y Sbjct: 31568 AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKY 31627 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEP 832 ++ N G + + +++ ++ P Sbjct: 31628 KVQLSNVFGTVDAILDVEIQDKPDKPTGP 31656 Score = 60.1 bits (139), Expect = 7e-07 Identities = 61/251 (24%), Positives = 95/251 (37%), Gaps = 34/251 (13%) Query: 480 YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539 Y + KK+ + D + + E+P P F L K G V+F + +P P Sbjct: 32595 YCRRTMKKIKRRTDTMRLLERP--------PEFTLPLYNKTAYVGENVRFGVTITVHPEP 32646 Query: 540 QITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 +TW++ IKP + + Y D + L I V +D +T VA+N G S + Sbjct: 32647 HVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAK 32706 Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L V L ++ T + P F + EG + E R+ Sbjct: 32707 LTV--TLHPPPTDST-------------------LRPMFKRLLANAECQEGQSVCFEIRV 32745 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 IP P + W G+ + NI + I + Y L I + G Y V A N G Sbjct: 32746 SGIPPPTLKWEKDGQPLSLGPNIEI-IHEGLDYY--ALHIRDTLPEDTGYYRVTATNTAG 32802 Query: 718 EASLPIVLKIK 728 S L+++ Sbjct: 32803 STSCQAHLQVE 32813 Score = 60.1 bits (139), Expect = 7e-07 Identities = 48/166 (28%), Positives = 78/166 (46%), Gaps = 20/166 (12%) Query: 1047 VVWERDGEIIKPKKN--KYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100 V W + G+ IKP N KY FE + +L I + + D+ EY+ + R ++SC A++ Sbjct: 32648 VTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKL 32707 Query: 1101 TVVELPPEIITRLQ--------NQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNH 1151 TV PP + L+ N + +G FEI ++ ++W KDG + + Sbjct: 32708 TVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN 32767 Query: 1152 IQLTIDG-KKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192 I++ +G L I D +D G Y + G++ C A L VE Sbjct: 32768 IEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 32813 Score = 59.3 bits (137), Expect = 1e-06 Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 2/126 (1%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534 +D N+ +Y+ K N + ++ T +EQ + P F +LR G V F+C + Sbjct: 8950 VDINDSGEYICKAENS-VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAIS 9008 Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 G ++W++ +K S + Q + DN ATL I + AG ++C A N G ASS Sbjct: 9009 GSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASS 9067 Query: 595 TTELIV 600 + LI+ Sbjct: 9068 SARLIL 9073 Score = 58.8 bits (136), Expect = 2e-06 Identities = 46/157 (29%), Positives = 79/157 (50%), Gaps = 16/157 (10%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ITN+ + +E + VVAVN +G + ++PIV K E P V S V+ G+ Sbjct: 24117 ITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIE---PDVKPAFSSYSVQVGQD 24173 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV-KDE-GVYTLKAEN 809 + + + G P+PTITW K+ P+K + D+ +T L K+ KD+ G Y + N Sbjct: 24174 LKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVAN 24233 Query: 810 SEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVK 845 G S ++T+++P +PP +F +++ + Sbjct: 24234 VVGQKTASIEIVTLDKP-----DPPKGPVKFDDVSAE 24265 Score = 58.8 bits (136), Expect = 2e-06 Identities = 65/275 (23%), Positives = 110/275 (40%), Gaps = 31/275 (11%) Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY-RFRAYAVNEVDISDASETTEYY-- 1471 Y + Y+ D + VK+ITK K + Y +YA E+ + E +YY Sbjct: 32542 YEITYE--DGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYA--ELFVKGVREVYDYYCR 32597 Query: 1472 KVIKETKIQSPTVEK---------PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + +K+ K ++ T+ PL N T E++ P+P VTWY+ G+K+ Sbjct: 32598 RTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKI 32657 Query: 1523 KTA----KATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVI 1573 K K T+E+ Y +A N +GE + V + P Sbjct: 32658 KPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTD 32717 Query: 1574 TISNEDIKQ-----KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KT 1627 + K+ + + G + GIPPP + W K+G L I + Sbjct: 32718 STLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDY 32777 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + I++ + Y + A+NTAG++S + L+V Sbjct: 32778 YALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 32812 Score = 58.8 bits (136), Expect = 2e-06 Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 2/128 (1%) Query: 476 DENNYTQYLQKKLNEKI--DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 D+ YT + K E KL V P + ++ P+F L +G +V FE +V Sbjct: 32686 DDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRV 32745 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P P + W + + + ++ ++ + L IR+ PED G + A N AG S Sbjct: 32746 SGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTS 32805 Query: 594 STTELIVE 601 L VE Sbjct: 32806 CQAHLQVE 32813 Score = 58.4 bits (135), Expect = 2e-06 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 8/148 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGES 751 L +T +K+ ++ + V A N G SLP + KE PP+++ P + + ++ G+ Sbjct: 19785 LVVTGLKEGKKYKFRVAARNAVG-VSLPREAEGVYEAKEQLLPPKILMP-EQITIKAGKK 19842 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAEN 809 + + A V G P PT W K V + D+ SI I+K KD G Y+L AEN Sbjct: 19843 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 19902 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFIN 837 S G +T + V +PP I+ Sbjct: 19903 SSG-TDTQKIKVVVMDAPGPPQPPFDIS 19929 Score = 57.6 bits (133), Expect = 4e-06 Identities = 38/197 (19%), Positives = 84/197 (42%), Gaps = 7/197 (3%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533 Q+PT +PL+++ G P P+V+W+RDG+ + T+ + + R Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLV 1592 Y A N G+ ++ + ++ + + ++ + G + + Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + GIP P V +Y++G ++++ ++ I+ + + I E S Y++ A+N+ G Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183 Query: 1653 TSSVEVTLKVYDKPSKP 1669 ++ L V + P Sbjct: 184 RATSTAELLVQGEEEVP 200 Score = 57.6 bits (133), Expect = 4e-06 Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E+ + AP F+ K + +G +V F CQV G P+P + W + + +++ Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKV 1130 Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 Y+ LVI F +DAG +T V +N G S++ L+ EA Sbjct: 1131 SYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175 Score = 57.2 bits (132), Expect = 5e-06 Identities = 26/91 (28%), Positives = 48/91 (52%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++L+P G FE V G P P +TWF++ + S + + ++ + T + Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3680 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + ED+G + C A+N G ++ EL+V Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCAAELLV 3711 Score = 56.8 bits (131), Expect = 6e-06 Identities = 44/153 (28%), Positives = 76/153 (49%), Gaps = 10/153 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + N+ + +E T+ V+AVN G + S P+++K +T E K +I + G+++ Sbjct: 21951 VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNI 22010 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810 + V+G P+PT+TW K ++ +K + T + TIL + D G Y L A N Sbjct: 22011 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNI 22070 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G E VIT++ + PP +F E++ Sbjct: 22071 VG--EVGDVITIQ--VHDIPGPPTGPIKFDEVS 22099 Score = 56.4 bits (130), Expect = 8e-06 Identities = 38/136 (27%), Positives = 61/136 (44%), Gaps = 5/136 (3%) Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A+ + V P E PP ++ + +TV E ++ L ++ P P++TWYR + I Sbjct: 924 AKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI 983 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 S F L+I +E DSG + C A N AG S + + V + F K Sbjct: 984 ESSIDFQITFQSGIARLMIREAFAE-DSGRFTCSAVNEAGTVSTSCYLAVQVSE-EFEKE 1041 Query: 934 ---LQKSYETEEGKTV 946 + + + TEE + V Sbjct: 1042 TTAVTEKFTTEEKRFV 1057 Score = 56.4 bits (130), Expect = 8e-06 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 1/100 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ + P F +L+ G V C++ G Q+ W+R +++ ++ Q + D Sbjct: 7096 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVD- 7154 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 NVATL I + +G ++C A N G ASS+ L P Sbjct: 7155 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 7194 Score = 56.4 bits (130), Expect = 8e-06 Identities = 87/445 (19%), Positives = 153/445 (34%), Gaps = 33/445 (7%) Query: 540 QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 ++TW++ +K + FQ +Y D L I + D G + C G + + + + Sbjct: 33675 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 33734 Query: 600 VEAPLSDHGSEMTVXXXXXXXXXXXXADILE----GIPPTFSKKP----KAQYVDEGSDI 651 +A S H + + + P S KP Q SD Sbjct: 33735 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDS 33794 Query: 652 LLECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 + + + A P P W G+ I + + D + L+I G YT Sbjct: 33795 VAKFAVKATGEPRPTAIWTKDGKAIT--QGGKYKLSEDKGGF--FLEIHKTDTSDSGLYT 33850 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP-RPTITW 768 N G S L IK + Q + K+ + + ++ ++ R Sbjct: 33851 CTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIK 33910 Query: 769 CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL-KAENSEGIAETSAVITVEEPTE 827 K + L K + +L ++VK +L K+ E I +TS E Sbjct: 33911 MSEAKSQEKLALKEEAS----KVLISEEVKKSAATSLEKSIVHEEITKTS---QASEEVR 33963 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 +AE F ++++ E + L A + + W N ++ SE G + Sbjct: 33964 THAEIKAFST---QMSINEGQRLVLKANIA--GATDVKWVLNGVELTNSEEYRYGVSGSD 34018 Query: 888 IELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 L I S D G C++ G K + ++ ++ +S EG+ Sbjct: 34019 QTLTIKQA-SHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQN 34077 Query: 946 VILECQTSHTVS--TKWYHNKKEIS 968 V+ C+ S S +W+ N IS Sbjct: 34078 VLFTCEISGEPSPEIEWFKNNLPIS 34102 Score = 56.0 bits (129), Expect = 1e-05 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ +AP F + LR + T + +C++ G +++WF+ I S +++ + + Sbjct: 5035 DRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT 5094 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + +IR V DAG FTC A N+ G S+ LIV+ P S Sbjct: 5095 ASLEIIR-VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 5134 Score = 56.0 bits (129), Expect = 1e-05 Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 1/108 (0%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559 P S+ AP F E+LR + S C+V G+P+P + W+RQ II +++ Sbjct: 31846 PKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQ 31905 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 L+I V +DA + A N G S T L VE P H Sbjct: 31906 EFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31953 Score = 56.0 bits (129), Expect = 1e-05 Identities = 70/320 (21%), Positives = 130/320 (40%), Gaps = 32/320 (10%) Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 L + T++ K EV+ P +D+ R +R+ G + +++ Q+ P +W Sbjct: 33277 LKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYH 33336 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD--VEMNVTILDKP 1381 N +++ + S +L I D+G Y+ N G A ++VT D Sbjct: 33337 NGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYT 33396 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKN-ITKT 1436 + + E+ S PE T T Y V +++ E S VK+ +T+T Sbjct: 33397 TYASQRRDEEVPRSVF------PELT--RTEAYAVSSFKKTSEMEASSSVREVKSQMTET 33448 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + S+ + + ++S ++ A+ E + + S T + +T + + + KP +++T Sbjct: 33449 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKI-----KTTLAARILTKP-RSMTVYEG 33502 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552 E +C G P P VTW R G+ L T+ T + + Y + Sbjct: 33503 ESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVV 33562 Query: 1553 FNDHGEVETSCVVGIQQKPV 1572 N G+ E + IQ+ V Sbjct: 33563 ENSEGKQEAEFTLTIQKARV 33582 Score = 55.6 bits (128), Expect = 1e-05 Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENR 1532 E + PT+ LKN+T E + L C G P P VTWYR+ +++++ + T+++ Sbjct: 937 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG 996 Query: 1533 -XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 + C A N+ G V TSC + +Q Sbjct: 997 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033 Score = 54.4 bits (125), Expect = 3e-05 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++++ P F +L+ G++ EC+V G + WF + I +Q + D N Sbjct: 6722 DRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSD-N 6780 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 V TL + + D G +TCVA N AG L V+ P S Sbjct: 6781 VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS 6821 Score = 53.6 bits (123), Expect = 6e-05 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T +++ P V P +G T +F C+V GYP+P++ W+ +I+ S+ F++ Y Sbjct: 1833 TDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY- 1891 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 D + L I + D G A+N G +L ++ Sbjct: 1892 -DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ 1930 Score = 53.6 bits (123), Expect = 6e-05 Identities = 44/151 (29%), Positives = 70/151 (46%), Gaps = 12/151 (7%) Query: 686 SDMHMYCSVLKITNVK-----KFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQV 737 SD C+ +K+T + +E ++ V A N +G S P L + K+ PP Sbjct: 23019 SDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAF 23077 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797 + V GE + + +G P P +TW K+N P+K + T + ++L K Sbjct: 23078 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 23137 Query: 798 --KDEGVYTLKAENSEGIA-ETSAVITVEEP 825 +D G Y +K NS G A ET VI +++P Sbjct: 23138 CREDVGHYVVKLTNSAGEAIETLNVIVLDKP 23168 Score = 52.8 bits (121), Expect = 1e-04 Identities = 35/169 (20%), Positives = 68/169 (40%), Gaps = 4/169 (2%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 AEN G++ + + E P +++T K +L ++ P+P I W Sbjct: 31434 AENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKW 31493 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 YR + + S + DG L + + E D G Y C+A+N G+ +++ + Sbjct: 31494 YRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE-DEGVYTCIATNEVGEVETSSKLLLQAT 31552 Query: 927 KVTFVKH-LQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDH 972 + L++ Y G T+ L + W+H +K + ++ Sbjct: 31553 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSEN 31601 Score = 52.4 bits (120), Expect = 1e-04 Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 3/130 (2%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV 533 +D+ + QY +NE + K + +E+ + P F ++L +G++ + E +V Sbjct: 9142 VDKGDSGQYTCYAVNE-VGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRV 9200 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G + W++ I+P+ + ++ + + N L +R+ DAG +TC N AG A Sbjct: 9201 AGSQPITVAWYKNNIEIQPTSNCEITFKN-NTLVLQVRKAGMNDAGLYTCKVSNDAGSAL 9259 Query: 594 STTELIVEAP 603 T+ ++++ P Sbjct: 9260 CTSSIVIKEP 9269 Score = 52.0 bits (119), Expect = 2e-04 Identities = 36/131 (27%), Positives = 66/131 (50%), Gaps = 5/131 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLP-IVLKIKTGEK-EPP--QVIEPLKSMI-VRQGES 751 + ++K Q+ ++ V AVN +G + + +I+ E+ E P ++ + LK + +R G S Sbjct: 30331 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 30390 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L V G P P ITW K + + +++S+ I+ D G YT++AEN Sbjct: 30391 LRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQS 30450 Query: 812 GIAETSAVITV 822 G + ++ V Sbjct: 30451 GKKSATVLVKV 30461 Score = 51.6 bits (118), Expect = 2e-04 Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 5/116 (4%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--I 791 PP ++ LK++ V +GESV L + G P PT+TW + + +++ I + Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 ++ +D G +T A N G TS + V+ E E +F T +EK Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKF---TTEEK 1054 Score = 51.6 bits (118), Expect = 2e-04 Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 10/117 (8%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMI-VRQGESVILSAQV 758 +F+ T V ++ E S P+ + E PP++ +KS++ V+ G +V L A V Sbjct: 20190 QFRAIARTAVNISPPSEPSDPVTI---LAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 20246 Query: 759 VGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 G P PT++W K+ KP + + + ++ + + KD G YT+ AENS G Sbjct: 20247 FGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR-KDSGDYTITAENSSG 20302 Score = 51.2 bits (117), Expect = 3e-04 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 4/120 (3%) Query: 486 KKLNEKIDKLPVFEK--PTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT 542 KK ++K + V K P + E S P+ V L+ S +F + G PRP Sbjct: 33752 KKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAI 33811 Query: 543 WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 W + I +++ +D L I + D+G +TC KN+AG SS+ +L ++A Sbjct: 33812 WTKDGKAITQGGKYKL-SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 33870 Score = 50.8 bits (116), Expect = 4e-04 Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 14/140 (10%) Query: 696 KITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQG 749 K+T ++ Q + V+AVN GE A +P + +K EPP++I + ++ G Sbjct: 18102 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD-RLEPPELILDANMAREQHIKVG 18160 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI---TILKPKKVKDEGVYTLK 806 +++ LSA + G P P +TW K ++ PTK+ D + ++ +D G+Y+L Sbjct: 18161 DTLRLSAIIKGVPFPKVTWKKEDRDA---PTKARIDVTPVGSKLEIRNAAHEDGGIYSLT 18217 Query: 807 AENSEGIAETSA-VITVEEP 825 EN G S V+ +++P Sbjct: 18218 VENPAGSKTVSVKVLVLDKP 18237 Score = 50.8 bits (116), Expect = 4e-04 Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 8/149 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEKEPPQVIE--P--LKSMIVRQGE 750 +T + + ++A N G S P I T ++ P ++E P +I++ GE Sbjct: 28842 VTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGE 28901 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKD-EGVYTLKAE 808 S+ + A V G P P +TW K+ + K + + S ++ +D GVYT++A+ Sbjct: 28902 SLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAK 28961 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFIN 837 N+ G A+ + V++ + P F N Sbjct: 28962 NASGSAKAEIKVKVQDTPGKVVGPIRFTN 28990 Score = 50.4 bits (115), Expect = 5e-04 Identities = 73/330 (22%), Positives = 129/330 (39%), Gaps = 42/330 (12%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E + F + K + EG + C++ P P IAW G+ I E + D Sbjct: 1287 EAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGR 1346 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 + L+I V EG YT A N +G A I +G+ +EP + Sbjct: 1347 ---ASLRIPVVLPEDEGIYTAFASNIKGNA-------ICSGKL----YVEPAAPL---GA 1389 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + I + + V R + P++ P + + P ++ + + Sbjct: 1390 PTYIPTLEPVSRIRSLSPRSVSRSPIRMSPAR----------MSPARMSPARMSPARMSP 1439 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 + ET +E E P+F+ + E T + +V P+P W+ + Sbjct: 1440 GRRLEET------DESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHD 1493 Query: 870 NEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VE 926 + I T + DG +++ S DSG++ VA N AG+SS +T++ VE Sbjct: 1494 GQQIVNDYTHKVVIKEDGTQSLIIVPATPS--DSGEWTVVAQNRAGRSSISVILTVEAVE 1551 Query: 927 ---KVTFVKHLQKSYETEEGKTVILECQTS 953 K FV+ L K+ +EG + ++ + + Sbjct: 1552 HQVKPMFVEKL-KNVNIKEGSQLEMKVRAT 1580 Score = 50.4 bits (115), Expect = 5e-04 Identities = 51/230 (22%), Positives = 89/230 (38%), Gaps = 12/230 (5%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQ 748 +V + N+ + E + V N GE+ + + T + + P E L+++ VR Sbjct: 31809 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 31868 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVY 803 + L +V G+P+P + W + K + A K G H + I+ D VY Sbjct: 31869 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL-IIASVTDDDATVY 31927 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 ++A N G +A + VE P + + P + + + + + P P Sbjct: 31928 QVRATNQGGSVSGTASLEVEVPAKIHL--PKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 31985 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 ITW + ++I + LV N D+G Y A N G Sbjct: 31986 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 32035 Score = 50.0 bits (114), Expect = 7e-04 Identities = 54/226 (23%), Positives = 96/226 (42%), Gaps = 22/226 (9%) Query: 705 EGTYTVVAVNREGEA--SLP---IVLKIKTGEKEPPQVIEPLKSMIV-------RQGESV 752 E ++ + A+N+ G + S P + ++ P+VI+ KS + G S Sbjct: 20088 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 20147 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 I+ V P W + N +P + ++ T L+ K A N Sbjct: 20148 IIGYFVEACKLPGDKWVRCNTAPHQIPQEE----YTATGLEEKAQYQFRAIARTAVNISP 20203 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNN 870 +E S +T+ EN P + ++ + +TVK + L A V P+P+++W ++ Sbjct: 20204 PSEPSDPVTI---LAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDG 20260 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 ++ P+E I L + +V+ + DSGDY A NS+G S Sbjct: 20261 TLLKPAEGIKMAMQRNLCTLELFSVNRK-DSGDYTITAENSSGSKS 20305 Score = 49.6 bits (113), Expect = 0.001 Identities = 33/118 (27%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + E E +A A+ V +E +P + + + + V E T + RVT P P + Sbjct: 1815 RIEELERMAHEGALTGVTTDQKEKQKPDIVLYP-EPVRVLEGETARFRCRVTGYPQPKVN 1873 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 WY N ++I S+ +DG + L I + S D+G+ K A N G H ++ I Sbjct: 1874 WYLNGQLIRKSKRFRVRYDGIHY-LDIVDCKS-YDTGEVKVTAENPEGVIEHKVKLEI 1929 Score = 49.6 bits (113), Expect = 0.001 Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 13/129 (10%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-----VRQGES 751 + N+ + Q + V AVN GE+ + L + + E P I+ S+ V+ GE Sbjct: 16283 VENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEP 16342 Query: 752 VILSAQVVGNPRPTITWCKN----NKPVKALP-TKSD-GDTHSITILK-PKKVK-DEGVY 803 V + A V G P P I W KN KP AL TK + + + T L PK V+ D+G Y Sbjct: 16343 VHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTY 16402 Query: 804 TLKAENSEG 812 T+ A N G Sbjct: 16403 TVTASNRLG 16411 Score = 49.2 bits (112), Expect = 0.001 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 6/124 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRN 859 + +KAEN G+ I +E +E PP L + + + VK T++ A + Sbjct: 18407 FRVKAENIVGLGLPDTTIPIE--CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGV 18464 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 PVP+ W + I E T D + L I N D+G+Y+ SN+AG + Sbjct: 18465 PVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR-DTGEYQITVSNAAGSKTVAV 18523 Query: 920 RVTI 923 +T+ Sbjct: 18524 HLTV 18527 Score = 49.2 bits (112), Expect = 0.001 Identities = 34/130 (26%), Positives = 66/130 (50%), Gaps = 11/130 (8%) Query: 691 YCSVLKITNVKKFQEGTYTVVA---VNREGEASLPIVLKIKTGEKEPPQVIEPLKS---M 744 Y V ++T ++++ + A V+ E++ PI++K + EPP+V+ +K + Sbjct: 26670 YFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVK---DDVEPPRVMMDVKFRDVI 26726 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGV 802 +V+ GE + ++A + G P P I+W K+ + +A D H++ +K +D G Sbjct: 26727 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQ 26786 Query: 803 YTLKAENSEG 812 Y L +N G Sbjct: 26787 YVLTLKNVAG 26796 Score = 48.8 bits (111), Expect = 0.002 Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 14/198 (7%) Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-- 1529 K+ +++P + + +++ T D G P P+ WY++G K++ + Y Sbjct: 2068 KIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWY 2127 Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE--DIKQKH 1584 +N A N GE + + +Q K +IT + E D+ K Sbjct: 2128 WPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE 2187 Query: 1585 KVGDEWLVTAVIEGIPP-PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 K + + T E P +V WYK+G ++ +Y + + K + I + S + Y Sbjct: 2188 K---DTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2244 Query: 1644 T---IEASNTAGTSSVEV 1658 + +E N T+ + V Sbjct: 2245 SCVLVEDENVKTTAKLIV 2262 Score = 48.8 bits (111), Expect = 0.002 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 TS + PIF +K P T G+ V EC+++G P ++W++ ++ + +++ Sbjct: 8318 TSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MS 8376 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 ++ + ++ I V D G + C A N G + + ++AP Sbjct: 8377 ENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAP 8418 Score = 48.0 bits (109), Expect = 0.003 Identities = 54/243 (22%), Positives = 85/243 (34%), Gaps = 21/243 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561 +E+ P F +KL FEC++ G P + W ++ + +M + Sbjct: 1697 KEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMI-N 1755 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGS---------- 609 + +L + D+G TC A N G ++ LIV E L + Sbjct: 1756 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1815 Query: 610 -EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 E D E P P+ V EG CR+ P+P + W Sbjct: 1816 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1875 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 G+ I + V + +H L I + K + G V A N EG + L+I+ Sbjct: 1876 LNGQLIRKSKRFRVRYDG-IH----YLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQ 1930 Query: 729 TGE 731 E Sbjct: 1931 QRE 1933 Score = 48.0 bits (109), Expect = 0.003 Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V + V G P P ++W + ++KP++ +M N+ TL + V +D+G +T Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR-NLCTLELFSVNRKDSGDYTI 20295 Query: 584 VAKNAAGFASSTTELIV 600 A+N++G S+T +L V Sbjct: 20296 TAENSSGSKSATIKLKV 20312 Score = 47.6 bits (108), Expect = 0.004 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +Q++ P F +KL GS++ EC+V G WF+ I S +++ + + Sbjct: 6159 DQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERS 6218 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 V +L + + ED +TC N AG + + L V+ P S Sbjct: 6219 V-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPS 6258 Score = 47.2 bits (107), Expect = 0.005 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P PE W+ +G ++ ND + + KE T + I S S ++T+ A N AG S Sbjct: 1480 VVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRS 1539 Query: 1655 SVEVTLKV 1662 S+ V L V Sbjct: 1540 SISVILTV 1547 Score = 47.2 bits (107), Expect = 0.005 Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 9/158 (5%) Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEV 1283 W+ + ++ D +I + ++LII T D E+T V + + L VE Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549 Query: 1284 VEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 VE P V+ + IK GS + + V P P+ W+ NS II K+ K I+ Sbjct: 1550 VEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGT 1609 Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 A+L I + D+ Y N G V + Sbjct: 1610 KGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNV 1647 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568 P FV+KL T G V+ VEG+ + W + +I+ S++ ++ + D N+ATL Sbjct: 7478 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFID-NIATL 7536 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + ++G + C KN AG + L V P Sbjct: 7537 QLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 7571 Score = 47.2 bits (107), Expect = 0.005 Identities = 47/207 (22%), Positives = 87/207 (42%), Gaps = 17/207 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGES 751 +T++ + E + V+A N G A +P +K+ + P ++ + + VRQG Sbjct: 31021 LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGV 31080 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L+ + G P P W K + + + +TH+ ++K D G Y L EN Sbjct: 31081 IRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKC 31140 Query: 812 GIAETSAVITVEEPTEENA-EPPLFINRFQEITVK-------EKGTIKLVARV-TRNPVP 862 G + + I V N+ E PL + Q +V+ + G ++ + R VP Sbjct: 31141 G--KKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVP 31198 Query: 863 SITWYRNNEIISPSETITQNFDGENIE 889 WY + + + + + EN+E Sbjct: 31199 KAAWYTIDSRVRGTSLVVKGLK-ENVE 31224 Score = 46.8 bits (106), Expect = 0.007 Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 3/124 (2%) Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536 E++ +Y+ + LN+ K K T +++ AP+ K+ P G +F C+++ Sbjct: 4352 EDHQGEYVCEALNDS-GKTATSAKLTVVKRA-APVIKRKIEPLEVALGHLAKFTCEIQSA 4409 Query: 537 PRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596 P + WF+ I S D +++L I D G +TC A N G S T Sbjct: 4410 PNVRFQWFKAGREIYES-DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4468 Query: 597 ELIV 600 L V Sbjct: 4469 TLTV 4472 Score = 46.8 bits (106), Expect = 0.007 Identities = 39/124 (31%), Positives = 57/124 (45%), Gaps = 6/124 (4%) Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQGESVILSAQVVG 760 +E V AVN G S P + K+P P + +IV +GE + + Sbjct: 15281 KEYVLRVRAVNAIG-VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRA 15339 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVK-DEGVYTLKAENSEGIAETSA 818 P PT++W K+ K VKA + + H S + PK V+ D G+YT+ EN G A S Sbjct: 15340 VPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASI 15399 Query: 819 VITV 822 + V Sbjct: 15400 NVKV 15403 Score = 46.4 bits (105), Expect = 0.009 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%) Query: 803 YTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 + +KA N EG A + + E L + ITV+ TI+++ARV P Sbjct: 18804 FRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRP 18863 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P ITW + +++ + + D +EL I D G Y A NS+G + A Sbjct: 18864 EPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEA-VRADHGKYIISAKNSSGHAQGSAI 18922 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILE 949 V + +++ ++L+ + T+E T+ E Sbjct: 18923 VNV-LDRPGPCQNLKVTNVTKENCTISWE 18950 Score = 46.4 bits (105), Expect = 0.009 Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 5/122 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A N+ G++ V E E+ P + + ++IT+K +++ A V P P Sbjct: 19798 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMP--EQITIKAGKKLRIEAHVYGKPHP 19855 Query: 863 SITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 + W + +E+++ S D +I L+I +V + DSG Y A NS+G + +V Sbjct: 19856 TCKWKKGEDEVVTSSHLAVHKADSSSI-LIIKDVTRK-DSGYYSLTAENSSGTDTQKIKV 19913 Query: 922 TI 923 + Sbjct: 19914 VV 19915 Score = 46.4 bits (105), Expect = 0.009 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 5/116 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNP 860 + + A N +G++E S I EP E P L + + + +T++ +++L+ V+ P Sbjct: 30342 FRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRP 30401 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P ITW + ++ I E+ L+I + + D+G Y A N +GK S Sbjct: 30402 PPVITWSKQGIDLASRAIIDTT---ESYSLLIVDKVNRYDAGKYTIEAENQSGKKS 30454 Score = 46.0 bits (104), Expect = 0.011 Identities = 28/121 (23%), Positives = 52/121 (42%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 KF+ + + GE + I +K + + ++V G + + A V G Sbjct: 17419 KFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 17478 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P PT+TW N + + T S ++K + +GVY+L A+N G + + ++ Sbjct: 17479 PPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVD 17538 Query: 822 V 822 V Sbjct: 17539 V 17539 Score = 46.0 bits (104), Expect = 0.011 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKP-VKALPTKSDGDTHSITILKPKKVK-DEGVY 803 VR G+++ + A+V G P P ITW K K V+ D + + + V+ D G Y Sbjct: 18847 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 18906 Query: 804 TLKAENSEGIAETSAVITV 822 + A+NS G A+ SA++ V Sbjct: 18907 IISAKNSSGHAQGSAIVNV 18925 Score = 45.6 bits (103), Expect = 0.015 Identities = 23/76 (30%), Positives = 37/76 (48%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ + I G P P V WY+ ++E+ ++ IT + + + I+E S ++T Sbjct: 957 GESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCS 1016 Query: 1647 ASNTAGTSSVEVTLKV 1662 A N AGT S L V Sbjct: 1017 AVNEAGTVSTSCYLAV 1032 Score = 45.6 bits (103), Expect = 0.015 Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 6/182 (3%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787 EK+ P ++ + + V +GE+ +V G P+P + W N + + K + DG H Sbjct: 1837 EKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG-IH 1895 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 + I+ K D G + AEN EG+ E + +++ + + E V E Sbjct: 1896 YLDIVDCKSY-DTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEP 1954 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 G ++ + PV + T + + +E IT E E + + + G Y+ + Sbjct: 1955 GKLQFEVQKVDRPVDT-TETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAI 2013 Query: 908 AS 909 + Sbjct: 2014 TA 2015 Score = 45.2 bits (102), Expect = 0.020 Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T+ E +P F K G + FEC V G +ITW + I+P ++ + Sbjct: 7190 TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC- 7248 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 N L I +V D+G +TC A N G + +L V+ P Sbjct: 7249 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290 Score = 45.2 bits (102), Expect = 0.020 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 14/179 (7%) Query: 747 RQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 + G S I+ V P T W + N++P+K L K + + P K E V + Sbjct: 15237 KNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEG------VVPDK---EYVLRV 15287 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK-EKGTIKLVARVTRNPVPSI 864 +A N+ G++E S + + + +P + + I ++ EK +I + R PVP++ Sbjct: 15288 RAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAV--PVPTV 15345 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +W+++ + + S+ +T D + L + D+G Y N G ++ V + Sbjct: 15346 SWHKDGKEVKASDRLTMKNDHISAHLEVPK-SVRADAGIYTITLENKLGSATASINVKV 15403 Score = 45.2 bits (102), Expect = 0.020 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 4/93 (4%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G+++ L+ + P P ++W G + P E I +A++ ++ C+ L++ +V + Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CT-LELFSVNRKD 20289 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV 737 G YT+ A N G S I LK+ P V Sbjct: 20290 SGDYTITAENSSGSKSATIKLKVLDKPGPPASV 20322 Score = 45.2 bits (102), Expect = 0.020 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 9/99 (9%) Query: 731 EKEPPQV-IEPL--KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDG 784 E +PP++ ++P +++V GES + A + G P PTI W K ++ + L KS Sbjct: 23464 EVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 23523 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 S+++ +V D G Y LKA+N G E S + V+ Sbjct: 23524 FATSLSVKDAVRV-DSGNYILKAKNVAG--ERSVTVNVK 23559 Score = 45.2 bits (102), Expect = 0.020 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 H P G V+ + G P P +WF + ++ S+ + VA L IRE D G Sbjct: 30676 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVE-THTKVAKLTIRETTIRDTG 30734 Query: 580 TFTCVAKNAAGFASSTTELIV 600 +T KN G S T ++I+ Sbjct: 30735 EYTLELKNVTGTTSETIKVII 30755 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 2/125 (1%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +E + + A+N +GI++ ++V ++ PP F F TV +K+ Sbjct: 23042 EEYSFRVSAQNEKGISDPRQ-LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG 23100 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P++TW+++N + + + N L I + E D G Y +NSAG++ Sbjct: 23101 RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE-DVGHYVVKLTNSAGEAIET 23159 Query: 919 ARVTI 923 V + Sbjct: 23160 LNVIV 23164 Score = 44.8 bits (101), Expect = 0.026 Identities = 36/136 (26%), Positives = 66/136 (48%), Gaps = 13/136 (9%) Query: 697 ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQ 748 ++ +++ E + V A N+ G E LP+++K + EPP++ P ++ VR Sbjct: 27361 VSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIK---EQLEPPEIDMKNFPSHTVYVRA 27417 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITI-LKPKKVKDEGVYTLK 806 G ++ + + G P P +T ++ P+KA + ++ ++TI LK D G Y + Sbjct: 27418 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 27477 Query: 807 AENSEGIAETSAVITV 822 A NS G + I V Sbjct: 27478 AANSSGTTKAFINIVV 27493 Score = 44.8 bits (101), Expect = 0.026 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 9/131 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQV---IEPLKSMIVRQGE 750 ++N+K + V AVN G+ PI + K E P++ + S+I + GE Sbjct: 28156 VSNLKPGVNYYFRVSAVNCAGQGE-PIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 28214 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808 V + G P PT+TW K+ K + + S +T S ++L +V D G Y L E Sbjct: 28215 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 28274 Query: 809 NSEGIAETSAV 819 N G ++S V Sbjct: 28275 NGVGEPKSSTV 28285 Score = 44.4 bits (100), Expect = 0.035 Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 2/76 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + L + +G+T EC+V ++ WF+ I S+ +++ D V LVI Sbjct: 13214 FTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADG-RVRKLVIH 13271 Query: 572 EVFPEDAGTFTCVAKN 587 + PED T+TC AK+ Sbjct: 13272 DCTPEDIKTYTCDAKD 13287 Score = 44.4 bits (100), Expect = 0.035 Identities = 32/114 (28%), Positives = 48/114 (42%), Gaps = 5/114 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNP 860 + + A N GI E V V E + P L ++ I V G I+++A V+ P Sbjct: 17420 FRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKP 17479 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P++TW N + TI + +VI N G Y +A N AG+ Sbjct: 17480 PPTVTWNMNERTLPQEATIETT--AISSSMVIKNCQRS-HQGVYSLLAKNEAGE 17530 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%) Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTI 1156 A V + PP +++ L+N V +G T E ++ + V W+++ +I+ S Q+T Sbjct: 934 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 +L I + +D+G ++C N T Sbjct: 994 QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023 Score = 44.0 bits (99), Expect = 0.046 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++ P F+ + + T G +F C V G P + W + A + PS ++++ D +N Sbjct: 4474 EAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKI-SDAENK 4532 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + + +D G ++C A N G ELI+ Sbjct: 4533 HILELSNLTIQDRGVYSCKASNKFGADICQAELII 4567 Score = 44.0 bits (99), Expect = 0.046 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 7/133 (5%) Query: 795 KKVKDEGVYTLK--AENS--EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 K++++ Y L+ A N+ EG + +TV EP E A L ++ I + T+ Sbjct: 15991 KEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVE-LDVSVKGGIQIMAGKTL 16049 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 ++ A VT PVP+ W + + + N G EL+I + + D G Y A+N Sbjct: 16050 RIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNV-GTKSELIIKDALRK-DHGRYVITATN 16107 Query: 911 SAGKSSHGARVTI 923 S G ARV + Sbjct: 16108 SCGSKFAAARVEV 16120 Score = 44.0 bits (99), Expect = 0.046 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 10/148 (6%) Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP---LF 835 PT G ++T LK E + + A NSEG+ E A + +E EPP L Sbjct: 25982 PTGLQGKQFTVTKLKENT---EYNFRICAINSEGVGEP-ATLPGSVVAQERIEPPEIELD 26037 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 + + + ++ T++L + P P + W + I++ I LVI NV Sbjct: 26038 ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI--EVTSSFTMLVIDNV 26095 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTI 923 + DSG Y N++G + V + Sbjct: 26096 -TRFDSGRYNLTLENNSGSKTAFVNVRV 26122 Score = 43.6 bits (98), Expect = 0.061 Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 12/191 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+ K + V+EG+++ + ++ +P P + W FK PD V ++ ++ Sbjct: 17043 MPPSIDLKEFME-VEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLYDTHVNKL 17100 Query: 692 C----SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 L I ++ G YT+ AVN G AS + L + G PP + P+K V Sbjct: 17101 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV-LGRPGPP--VGPIKFESVS 17157 Query: 748 QGESVI--LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYT 804 + + + G + T + + + + T PK ++ E V+ Sbjct: 17158 ADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFR 17217 Query: 805 LKAENSEGIAE 815 + A+N GI E Sbjct: 17218 IMAQNKYGIGE 17228 Score = 43.6 bits (98), Expect = 0.061 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 14/153 (9%) Query: 700 VKKFQEGT---YTVVAVNREGEASLPIVLKIKTGEKE--PPQV-IEPLKSMIVRQGESVI 753 VK +EG Y V AVN G+ K T + E PP + ++ + +R GE+ Sbjct: 17705 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFA 17764 Query: 754 LSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 L+ + G P+P ++W K+ V K+ T ++ +K K+ D G Y + ENS Sbjct: 17765 LTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKR-SDSGKYCVVVENS 17823 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G + + V + PP+ F E+T Sbjct: 17824 TGSRKGFCQVNV----VDRPGPPVGPVSFDEVT 17852 Score = 43.2 bits (97), Expect = 0.081 Identities = 40/134 (29%), Positives = 66/134 (49%), Gaps = 12/134 (8%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM----AP-IFVE-KLRPKHTPD-GSTV 527 ++E + Y K LN + P +PT E Q++ AP IF++ KL T G+ + Sbjct: 14578 LEEGKWYAYRVKALNRQGASKP--SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 14635 Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTFTCVAK 586 + V G P P+ITW + I+K QD ++ ++ +T+ I + D GT+ A Sbjct: 14636 ELPATVTGKPEPKITWTKADMILK--QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAV 14693 Query: 587 NAAGFASSTTELIV 600 N G A++ E+ V Sbjct: 14694 NVCGRATAVVEVNV 14707 Score = 43.2 bits (97), Expect = 0.081 Identities = 30/119 (25%), Positives = 58/119 (48%), Gaps = 7/119 (5%) Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSA-QVVGNPRPT 765 T A++ E++ I+ K + + P V++P + ++ G++++L+A ++G P P Sbjct: 21280 TAGAISAPSESTETIICKDEY--EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPK 21337 Query: 766 ITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +W K K ++ + + T S+ +K KD G YT+ A N G +TV Sbjct: 21338 SSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 21396 Score = 43.2 bits (97), Expect = 0.081 Identities = 32/106 (30%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Query: 712 AVNREGEASLPIVLKIKTGEKEPPQV-IEPL--KSMIVRQGESVILSAQVVGNPRPTITW 768 A+++ +++ PI K E E P++ ++P +++V GE+ L A V G P PTI W Sbjct: 24530 AISKPSDSTGPITAK---DEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW 24586 Query: 769 CKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + +K ++ A + D ++ I+K D G Y L+A N G Sbjct: 24587 LRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 24632 Score = 43.2 bits (97), Expect = 0.081 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 3/105 (2%) Query: 499 EKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 EK T+ + ++A + K R +G + +F C +G P P +TW R+ ++ S Sbjct: 33475 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 33534 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 Q+ +T I V D G ++ V +N+ G + L ++ Sbjct: 33535 QV-TTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 33578 Score = 43.2 bits (97), Expect = 0.081 Identities = 18/66 (27%), Positives = 29/66 (43%) Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 +G P P V W + G L + +TT + S I ++ S Y++ N+ G Sbjct: 33512 DGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEA 33571 Query: 1657 EVTLKV 1662 E TL + Sbjct: 33572 EFTLTI 33577 Score = 42.7 bits (96), Expect = 0.11 Identities = 31/129 (24%), Positives = 61/129 (47%), Gaps = 12/129 (9%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPV 861 + +KA N+ G+++ SA + + + P + + F E+ E+GT + +VA++ P Sbjct: 17016 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEV---EEGTNVNIVAKIKGVPF 17072 Query: 862 PSITWYR-------NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P++TW++ N E + + + + LVI D+G Y A N+ G Sbjct: 17073 PTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQ-SRRSDTGLYTITAVNNLGT 17131 Query: 915 SSHGARVTI 923 +S R+ + Sbjct: 17132 ASKEMRLNV 17140 Score = 42.7 bits (96), Expect = 0.11 Identities = 25/120 (20%), Positives = 57/120 (47%), Gaps = 4/120 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQV---IEPLKSMIVRQGESV 752 + +++ ++ + + A+N G ++ ++ E+E P E ++++VR G S+ Sbjct: 21662 VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSI 21721 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + + G P P +TW K+N +K + ++ ++ I+ D G + + EN G Sbjct: 21722 RIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 21781 Score = 42.7 bits (96), Expect = 0.11 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDE 800 ++I++ GE+ L A V G P PT+ W K+ K ++ A D + + K +D Sbjct: 22397 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 22456 Query: 801 GVYTLKAENSEGIAE 815 G YTL A N G A+ Sbjct: 22457 GAYTLTATNPGGFAK 22471 Score = 42.7 bits (96), Expect = 0.11 Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 10/154 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +++ + + E + + A+N+ G + PI+++ K + +E K + +R G Sbjct: 23825 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAG 23884 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 S+ L + G P P + W K + ++ + + +L D G YTL EN Sbjct: 23885 GSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLEN 23944 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 S G SA +TV + PP+ + + EIT Sbjct: 23945 SSG--TKSAFVTVR--VLDTPSPPVNL-KVTEIT 23973 Score = 42.7 bits (96), Expect = 0.11 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 7/135 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753 I+ + +E + V AVN +G + P L + ++ P V P + V+ E + Sbjct: 26282 ISGLTAGEEYVFRVAAVNEKGRSD-PRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSE 811 + G P+ T+ W K+ + +K + + ++T L K+ +D G Y L NS Sbjct: 26341 IDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA 26400 Query: 812 G-IAETSAVITVEEP 825 G I +I ++ P Sbjct: 26401 GSITVPITIIVLDRP 26415 Score = 42.7 bits (96), Expect = 0.11 Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +++ + V+G P P++TWF+ I+ + ++ D +L +R+ + G +T Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI-TDVLGSTSLFVRDATRDHRGVYTV 28958 Query: 584 VAKNAAGFASSTTELIVE 601 AKNA+G A + ++ V+ Sbjct: 28959 EAKNASGSAKAEIKVKVQ 28976 Score = 41.9 bits (94), Expect = 0.19 Identities = 47/216 (21%), Positives = 86/216 (39%), Gaps = 8/216 (3%) Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISD 1247 +T + P+ FT L +++ +T + +V+W++ VI T IS Sbjct: 1 MTTQAPT--FTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF 58 Query: 1248 VKKRT-LIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 R L I T+ + Y+ + A ST +L V+ PP V + +++G Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQG 118 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 S V L V P P ++ + I+ + S + SL I + D+G Y + Sbjct: 119 SQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNA 178 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 N+ G A + + + P K + ++ I+ Sbjct: 179 TNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQIS 214 Score = 41.9 bits (94), Expect = 0.19 Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 4/100 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PPT K V EG + LEC + P P + W + +I + + +S + Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGI---- 997 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 + L I G +T AVN G S L ++ E+ Sbjct: 998 ARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEE 1037 Score = 41.9 bits (94), Expect = 0.19 Identities = 39/131 (29%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Query: 700 VKKFQEGT---YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMI-VRQGESV 752 VK+ +EG V AVN GE + E + P +E +K I + G+++ Sbjct: 15990 VKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTL 16049 Query: 753 ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + A V G P PT W K + K + T S I+K KD G Y + A NS Sbjct: 16050 RIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSC 16109 Query: 812 GIAETSAVITV 822 G +A + V Sbjct: 16110 GSKFAAARVEV 16120 Score = 41.9 bits (94), Expect = 0.19 Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 7/133 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREG--EA-SLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGE 750 +I+ + + QE V A+N+ G EA S+P +K + + P + E K ++VR G Sbjct: 24908 EISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGG 24967 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 S + G P P ITW + G ++ + D G Y LK ENS Sbjct: 24968 SARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENS 25027 Query: 811 EGIAETSAVITVE 823 G SA +TV+ Sbjct: 25028 SG--SKSAFVTVK 25038 Score = 41.9 bits (94), Expect = 0.19 Identities = 50/230 (21%), Positives = 94/230 (40%), Gaps = 10/230 (4%) Query: 702 KFQEGTYTVVA--VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI--VRQGESVILSAQ 757 ++Q TY + A V++ EAS PI+ + P+V + +S + + + ++ Sbjct: 29837 EYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSK 29896 Query: 758 VVGN--PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN--SEGI 813 VVG R ++ + + +K T + ++T L + V A S+G Sbjct: 29897 VVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGS 29956 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 T V +E AE ++ +T++ + L A V P P I W + ++ + Sbjct: 29957 ESTGPVTCRDEYAPPKAELDARLHG-DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL 30015 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 E ++ + G+ VI D DSG Y N++G + V + Sbjct: 30016 DLCEKVSLQYTGKRATAVIKFCDRS-DSGKYTLTVKNASGTKAVSVMVKV 30064 Score = 41.9 bits (94), Expect = 0.19 Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 5/123 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNP 860 + + A N+ G E + V + TE P ++ R+QE I V++ G I+L + P Sbjct: 31032 FRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP 31091 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P W + + IS I + + ELVI D DSG Y V N GK + + Sbjct: 31092 FPICKWTKEGQDISKRAMIATS--ETHTELVIKEADRG-DSGTYDLVLENKCGKKAVYIK 31148 Query: 921 VTI 923 V + Sbjct: 31149 VRV 31151 Score = 41.5 bits (93), Expect = 0.25 Identities = 39/159 (24%), Positives = 63/159 (39%), Gaps = 11/159 (6%) Query: 450 TSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEK-IDKLPVFEKPTSEEQSM 508 T + W K EE + + L++ Y ++ K +N + K P ++ Sbjct: 16985 TKKEAWRQCNKRDVEELQFT-VEDLVEGGEY-EFRVKAVNAAGVSKPSATVGPCDCQRPD 17042 Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD------ 562 P ++ +G+ V +++G P P +TWF+ KP + YD Sbjct: 17043 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPP-KKPDNKEPVLYDTHVNKLV 17101 Query: 563 -DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 D+ TLVI + D G +T A N G AS L V Sbjct: 17102 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 17140 Score = 41.5 bits (93), Expect = 0.25 Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--D 799 K++I+R G ++ L V G P P ITW K N ++ T T L+ + V D Sbjct: 20628 KTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYD 20687 Query: 800 EGVYTLKAENSEGIAETSAVITV 822 G Y L ENS G E + V+ V Sbjct: 20688 AGKYILTLENSCGKKEYTIVVKV 20710 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/139 (20%), Positives = 61/139 (43%), Gaps = 6/139 (4%) Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 H++T L ++ ++ ++A+N +G++E +T + P + ++ + T+ Sbjct: 30621 HTVTSLNEG---EQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHV 30677 Query: 847 KG--TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 ++LV + P P+ +W+ + SE +T + +L I D+G+Y Sbjct: 30678 PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR-DTGEY 30736 Query: 905 KCVASNSAGKSSHGARVTI 923 N G +S +V I Sbjct: 30737 TLELKNVTGTTSETIKVII 30755 Score = 41.1 bits (92), Expect = 0.33 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 2/75 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + ++AEN+ GI+E S + + P + + E VK I L A ++ +P P Sbjct: 15579 FRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE--VKRGDEIALDASISGSPYP 15636 Query: 863 SITWYRNNEIISPSE 877 +ITW ++ +I P E Sbjct: 15637 TITWIKDENVIVPEE 15651 Score = 41.1 bits (92), Expect = 0.33 Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 5/131 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEK--EPPQVIEP--LKSMIVRQGES 751 +T+++ +E + V A+N G+ S + IK ++ P I+ ++ +VR G S Sbjct: 29242 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGAS 29301 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L G P PT W K + + D+ S ++ D G YTL EN+ Sbjct: 29302 IRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNS 29361 Query: 812 GIAETSAVITV 822 G + + V Sbjct: 29362 GSKSITFTVKV 29372 Score = 40.7 bits (91), Expect = 0.43 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 +SN DI +GD ++ + GIP P++ W+ NG L +Y + I Sbjct: 3509 VSNADIS----MGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3564 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 K +YT ASN G + LK+ K Sbjct: 3565 TKLEDEGEYTCMASNDYGKTICSAYLKINSK 3595 Score = 40.7 bits (91), Expect = 0.43 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F +K P GS V +C++ G P ++ W + ++ S+ F++ + +L Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFD-TSLH 7443 Query: 570 IREVFPEDAGTFTCVAKNAAG 590 I + D G + C A N G Sbjct: 7444 ILNLEASDVGEYHCKATNEVG 7464 Score = 40.7 bits (91), Expect = 0.43 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T++ +V+G P P ITW ++ ++ + + D V L I+E D G + Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRV-ELQIKEAVRADHGKYII 18908 Query: 584 VAKNAAGFASST 595 AKN++G A + Sbjct: 18909 SAKNSSGHAQGS 18920 Score = 40.7 bits (91), Expect = 0.43 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582 G ++ E V G PRP I+W + +K Q ++ ++ +T++ I+E +D G +T Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLK--QTTRVNVEETATSTVLHIKEGNKDDFGKYT 25310 Query: 583 CVAKNAAGFASSTTELIV 600 A N+AG A+ +IV Sbjct: 25311 VTATNSAGTATENLSVIV 25328 Score = 40.7 bits (91), Expect = 0.43 Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 9/125 (7%) Query: 705 EGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQ 757 E + V +VN+ G ++S P + K + E+EP I E K++IV+ G S ++ Sbjct: 27079 EYVFRVKSVNKVGASDPSDSSDPQIAKER--EEEPLFDIDSEMRKTLIVKAGASFTMTVP 27136 Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 G P P + W K + ++ D+ + ++ D G YTL +N A + Sbjct: 27137 FRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 27196 Query: 818 AVITV 822 V+ V Sbjct: 27197 LVVKV 27201 Score = 40.7 bits (91), Expect = 0.43 Identities = 40/142 (28%), Positives = 66/142 (46%), Gaps = 11/142 (7%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASL----PIVLK--IKTGEKEPPQVIEPLKSMIVRQ 748 ++++ +K+ + V A N +G + PI +K I T E + + P + VR Sbjct: 28447 IEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDI--PGAQVTVRI 28504 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLK 806 G +V L G P+P+I+W K+ P+K T + L K K E G YT+ Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564 Query: 807 AENSE-GIAETSAVITVEEPTE 827 +N+ IA VIT+ P++ Sbjct: 28565 LDNAVCRIAVPITVITLGPPSK 28586 Score = 40.3 bits (90), Expect = 0.57 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 6/127 (4%) Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNP 860 +Y + + E+ V T E +E+ + P+ + + TVK TI+L A V P Sbjct: 19097 IYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKP 19156 Query: 861 VPSITWYRNNEI--ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P + W ++ + ++ S + + ++ + +T D G Y A+N+AG S Sbjct: 19157 FPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKA-KRSDGGKYVVTATNTAG--SFV 19213 Query: 919 ARVTIDV 925 A T++V Sbjct: 19214 AYATVNV 19220 Score = 40.3 bits (90), Expect = 0.57 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ E + G P+P ITW + +K + + D ++ TL I+E +D G + Sbjct: 24171 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDDGGQYGI 24229 Query: 584 VAKNAAGFASSTTELI 599 N G +++ E++ Sbjct: 24230 TVANVVGQKTASIEIV 24245 Score = 40.3 bits (90), Expect = 0.57 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPEDAGTF 581 +G + C G P P++TW I + + + ++ D++ TL+I +V +D G + Sbjct: 34269 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 34328 Query: 582 TCVAKNAAGFASSTTELIVEA 602 T N G S+T + + + Sbjct: 34329 TLSLGNEFGSDSATVNIHIRS 34349 Score = 39.9 bits (89), Expect = 0.75 Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 13/200 (6%) Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 Y V S + E E +E + P + PL++ T + C G KV Sbjct: 3317 YGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKV 3375 Query: 1514 TWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 +WY KK+K ++ +E+ Y +A N G+V ++ + ++ Sbjct: 3376 SWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435 Query: 1570 KPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI------ 1621 I ++I+ + K ++A EG+ E+ K LE E + Sbjct: 3436 PESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYSTKFD 3495 Query: 1622 TTKEKTSVIRIKELKRSHSS 1641 + KE T I IKE+ + S Sbjct: 3496 SEKEGTGPIFIKEVSNADIS 3515 Score = 39.9 bits (89), Expect = 0.75 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 6/106 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P+ + G D+ +E ++ P P+I+W+ GE + ++V + Sbjct: 25237 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV----EETAT 25292 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPP 735 +VL I K G YTV A N G A +L +++ K G P Sbjct: 25293 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP 25338 Score = 39.9 bits (89), Expect = 0.75 Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 4/79 (5%) Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYT 804 R G SV L A + G P PTI W K++K ++ AL + + ++K + G Y Sbjct: 27812 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYE 27871 Query: 805 LKAENSEGIAETSAVITVE 823 LK N+ G A SA I V+ Sbjct: 27872 LKLRNAMGSA--SATIRVQ 27888 Score = 39.5 bits (88), Expect = 0.99 Identities = 53/244 (21%), Positives = 91/244 (37%), Gaps = 20/244 (8%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXX 1538 P E+ L+++T + + +TC F VP K W+R+G+ LK K E++ Sbjct: 9672 PAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTI 9730 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE- 1597 + D +ETS + I+ +P+ Q V + T E Sbjct: 9731 ADVRAEDQGQYTCKYED---LETSAELRIEAEPIQFTKRI---QNIVVSEHQSATFECEV 9784 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI--------EASN 1649 V WYK +L ++YN + + I + Y++ EA + Sbjct: 9785 SFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARS 9844 Query: 1650 TAGTSSVEVTLKVYDKPSK-PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 TA +K+ KP P+ V + + +V E PP+ + L E+ +P Sbjct: 9845 TAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKP 9904 Query: 1709 DNNR 1712 R Sbjct: 9905 PPKR 9908 Score = 39.5 bits (88), Expect = 0.99 Identities = 33/134 (24%), Positives = 65/134 (48%), Gaps = 14/134 (10%) Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV----- 1658 V+W+KN KL + I+++ KT + +KE+ S+ + + T+ ++V Sbjct: 12531 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADP 12590 Query: 1659 --TLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGG--LELTKYAIEKHEPDNNRW 1713 T+K++DK + + + ++ E+S++ V ++W DG + KY+I+ Sbjct: 12591 YFTVKLHDKTAVEKDEITLKCEVSKD-VPVKW---FKDGEEIVPSPKYSIKADGLRRILK 12646 Query: 1714 IKVADVDRDVETYC 1727 IK AD+ E C Sbjct: 12647 IKKADLKDKGEYVC 12660 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 4/100 (4%) Query: 504 EEQSMAPIFVEKLRPKHTP---DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 +EQ P K P HT GS ++ + + G P P++T R +K + F Sbjct: 27395 KEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEI 27454 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +N+ T+ ++E DAG + A N++G + ++V Sbjct: 27455 TAENL-TINLKESVTADAGRYEITAANSSGTTKAFINIVV 27493 Score = 39.5 bits (88), Expect = 0.99 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V E +G P+P I+W + +K S +F + +N TL I+ E G +T Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKES-EFVRFSKTENKITLSIKNAKKEHGGKYTV 28563 Query: 584 VAKNA 588 + NA Sbjct: 28564 ILDNA 28568 Score = 39.5 bits (88), Expect = 0.99 Identities = 34/101 (33%), Positives = 45/101 (44%), Gaps = 14/101 (13%) Query: 1201 RLPEFILVPANTDAYL--------TVEIPDETLDVTWYKKKSVI---EDTEKFTLISDVK 1249 R PEF L N AY+ T+ + E VTWYK I ++ +K+T SD Sbjct: 32615 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEP-HVTWYKSGQKIKPGDNDKKYTFESDKG 32673 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP 1288 L I T DD EYT V + + + K K+ V PP Sbjct: 32674 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPP 32714 Score = 39.1 bits (87), Expect = 1.3 Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 9/142 (6%) Query: 808 ENSEGIAETSAVITVEEPTEENAEP-----PLFINRFQEITVKEKGTIKLVARVTRNPVP 862 E + V+T TEE A P P FI + + E G++ +V NP P Sbjct: 1052 EEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKP 1111 Query: 863 SITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 + W ++ ++ ++ N +LVI+ ++ D+G+Y V N G++S A Sbjct: 1112 HVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFAD-DAGEYTIVVRNKHGETSASAS 1170 Query: 921 VTIDVEKVTFVKHLQKS-YETE 941 + + + +K Q+ Y+T+ Sbjct: 1171 LLEEADYELLMKSQQEMLYQTQ 1192 Score = 39.1 bits (87), Expect = 1.3 Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 3/77 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P++ WYK+G ++++ + Y + ++ + +RI + YT ASN G + Sbjct: 1314 MSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNA 1373 Query: 1655 SVEVTLKVYDKPSKPEG 1671 + K+Y +P+ P G Sbjct: 1374 I--CSGKLYVEPAAPLG 1388 Score = 39.1 bits (87), Expect = 1.3 Identities = 39/123 (31%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGE-KEPPQV---IEPLKSMIVRQGE 750 +T++ + QE + V A N+ G P LK IK E EPP++ K +IVR G Sbjct: 19491 VTSLDENQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGC 19549 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVKDEGVYTLKAEN 809 + L A V G P P +TW K + D DT + ++ D G Y+L N Sbjct: 19550 PIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVN 19609 Query: 810 SEG 812 G Sbjct: 19610 PAG 19612 Score = 39.1 bits (87), Expect = 1.3 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Query: 839 FQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 + E+ GT +KL A ++ P P+I WY++++ + + + + ++I + D Sbjct: 27805 YTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDAD- 27863 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTI 923 ++SG Y+ N+ G +S RV I Sbjct: 27864 RLNSGCYELKLRNAMGSASATIRVQI 27889 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/129 (22%), Positives = 54/129 (41%), Gaps = 4/129 (3%) Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVA 854 + K++ + + A N G+ E + + VE E A L + + V+ +I++ Sbjct: 21666 QTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFV 21725 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 + P P +TW ++N + I E+ L+I + D+G + N AGK Sbjct: 21726 PIKGRPAPEVTWTKDNINLKNRANIENT---ESFTLLIIPECNRYDTGKFVMTIENPAGK 21782 Query: 915 SSHGARVTI 923 S V + Sbjct: 21783 KSGFVNVRV 21791 Score = 38.7 bits (86), Expect = 1.7 Identities = 56/251 (22%), Positives = 103/251 (41%), Gaps = 28/251 (11%) Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 T K + TY V ++ E ++ + + G EP + EP+K+ L+ Sbjct: 21843 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDS-LNIM 21901 Query: 758 VVGNPRPTITWCKNNKP---------VKALPTKSDGDTHSITI------LKPKKVKDEGV 802 + ++ W K ++A SD TH T+ ++ +E Sbjct: 21902 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYT 21961 Query: 803 YTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINR-FQEITVKEKG-TIKLVARVTR 858 + + A NS G + S + V+E T P L + +Q++ + + G IK+ V Sbjct: 21962 FQVMAVNSAGRSAPRESRPVIVKEQT---MLPELDLRGIYQKLVIAKAGDNIKVEIPVLG 22018 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917 P P++TW + ++I+ ++ + NF+ ++ N DSG Y A N G+ Sbjct: 22019 RPKPTVTWKKGDQILKQTQRV--NFETTATSTILNINECVRSDSGPYPLTARNIVGEV-- 22074 Query: 918 GARVTIDVEKV 928 G +TI V + Sbjct: 22075 GDVITIQVHDI 22085 Score = 38.7 bits (86), Expect = 1.7 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 7/120 (5%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNPVPS 863 A NSEG+ E A++ E+ PP L + + +T++ T++L + P P Sbjct: 22760 AMNSEGLGEP-ALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPE 22818 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W R++ +I L++ NV + DSG Y NS+G S V + Sbjct: 22819 VKWARDHGESLDKASIEST--SSYTLLIVGNV-NRFDSGKYILTVENSSGSKSAFVNVRV 22875 Score = 38.7 bits (86), Expect = 1.7 Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 8/145 (5%) Query: 784 GDTHSITILKPKKV-KDEGVYTLKAENSEGIAET----SAVITVEEPTEENAEPPLFINR 838 G T +T + V K E + +KA+N G +E S+VI E E A+ N Sbjct: 29523 GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITN- 29581 Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898 Q IT K + ++ P P +TW + ++ ++ + L + + Sbjct: 29582 -QLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKD-SMR 29639 Query: 899 IDSGDYKCVASNSAGKSSHGARVTI 923 DSG Y N+AG + V + Sbjct: 29640 GDSGRYFLTLENTAGVKTFSVTVVV 29664 Score = 38.7 bits (86), Expect = 1.7 Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +E + H G V + G P P ITW + +I + +Q+ + + Sbjct: 31955 PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVF 32014 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMT 612 V +DAG + AKN G T EL + + P G +++ Sbjct: 32015 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVS 32058 Score = 38.3 bits (85), Expect = 2.3 Identities = 39/181 (21%), Positives = 75/181 (41%), Gaps = 12/181 (6%) Query: 1507 GVPQPKVTWYRDGKKL---KTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P+ W+ DG+++ T K + + +A N G Sbjct: 1482 GRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSI 1541 Query: 1562 SCVVGIQ--QKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617 S ++ ++ + V + E +K + K G + + G P P+++W KN + + K Sbjct: 1542 SVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1601 Query: 1618 -EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVI 1674 + I + + ++I S+ YT A N AG T+ +V ++V +PE +I Sbjct: 1602 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLI 1661 Query: 1675 M 1675 + Sbjct: 1662 I 1662 Score = 38.3 bits (85), Expect = 2.3 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 9/97 (9%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSI--- 789 P I+ + M V +G +V + A++ G P PT+TW K KP P D + + Sbjct: 17044 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 17103 Query: 790 ---TILKPK-KVKDEGVYTLKAENSEGIAETSAVITV 822 T++ P+ + D G+YT+ A N+ G A + V Sbjct: 17104 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 17140 Score = 38.3 bits (85), Expect = 2.3 Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 13/181 (7%) Query: 640 PKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 P AQ V G ++ LE P+P I+WL G + E + + + L I Sbjct: 28496 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENK----ITLSIK 28551 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 N KK G YTV+ N ++PI + I G P+ P++ ++ +SVILS V Sbjct: 28552 NAKKEHGGKYTVILDNAVCRIAVPITV-ITLGPPSKPK--GPIRFDEIK-ADSVILSWDV 28607 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSI---TILKPKKVKD-EGVYTLKAENSEGIA 814 + C + + + T S+ T P VKD E + ++AEN G++ Sbjct: 28608 PEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVS 28667 Query: 815 E 815 + Sbjct: 28668 Q 28668 Score = 38.3 bits (85), Expect = 2.3 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 1592 VTAVIEG--IPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEAS 1648 +T V+E + EV WYK+G KL+ + + + + T ++I L S +Y E S Sbjct: 33662 LTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEIS 33721 Query: 1649 NTAGTSSVEV 1658 GTS + Sbjct: 33722 GEGGTSKTNL 33731 Score = 37.9 bits (84), Expect = 3.0 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+TV+F + G P P W + IK + + + D+ + + L I+ D G + Sbjct: 18452 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-SVLTIKNCLRRDTGEYQI 18510 Query: 584 VAKNAAGFASSTTELIV 600 NAAG + L V Sbjct: 18511 TVSNAAGSKTVAVHLTV 18527 Score = 37.9 bits (84), Expect = 3.0 Identities = 32/156 (20%), Positives = 69/156 (44%), Gaps = 10/156 (6%) Query: 673 EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 + + +EN + + + S +T K++ T+ V A N GE + + + + Sbjct: 20848 DFLTEENKWQRVMKSLSLQYSAKDLTEGKEY---TFRVSAENENGEGTPSEITVVARDDV 20904 Query: 733 EPPQV-IEPLKSM--IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 P + ++ L + + ++ + L + G P P+++W K P+ A T+ ++ ++ Sbjct: 20905 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPL-ATDTRVSVESSAV 20963 Query: 790 T---ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 I+ + D G YT+ +N G E + I V Sbjct: 20964 NTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20999 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/116 (20%), Positives = 46/116 (39%), Gaps = 5/116 (4%) Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT--VKEKGTIKLVARVT 857 E + + AEN G S + V ++ P L + ++ KE +L + Sbjct: 20877 EYTFRVSAENENGEGTPSEITVVAR--DDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIK 20934 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P PS++W + + ++ ++ N L++ + D+G Y N AG Sbjct: 20935 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS-DAGKYTITLKNVAG 20989 Score = 37.9 bits (84), Expect = 3.0 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 9/131 (6%) Query: 798 KDEGVYTLKAENSEGIAETSAV---ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 K E + + A N G+ E + V I VEE E + L + + I ++ G+++L Sbjct: 23833 KHEYNFRICAINKAGVGEHADVPGPIIVEEKLEA-PDIDLDLELRKIINIRAGGSLRLFV 23891 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 + P P + W + + I + I + LV+ NV + DSG Y NS+G Sbjct: 23892 PIKGRPTPEVKWGKVDGEIRDAAII--DVTSSFTSLVLDNV-NRYDSGKYTLTLENSSGT 23948 Query: 915 SSHGARVTIDV 925 S A VT+ V Sbjct: 23949 KS--AFVTVRV 23957 Score = 37.5 bits (83), Expect = 4.0 Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 1/90 (1%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P IV Y R+ G +PQP W +N ++I+K K + D L I Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG-IHYLDI 1899 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 ++ D G K+ EN G + ++ + I Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEI 1929 Score = 37.5 bits (83), Expect = 4.0 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Query: 509 APIFVEKLRPKHT------PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 A +FVE L T P+ T FEC+V + P + W + I+ S+ F++ Sbjct: 2875 AKLFVETLHITKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVV-Q 2932 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASST-TELIVEAPLSDHGSE 610 + L+I ED+ +T V N A+ T T +++ + L D +E Sbjct: 2933 GKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAE 2981 Score = 37.5 bits (83), Expect = 4.0 Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ E V G P P W + + S ++ D + + L+I++V +D+G ++ Sbjct: 19840 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSS-SILIIKDVTRKDSGYYSL 19898 Query: 584 VAKNAAGFASSTTELIV-EAP 603 A+N++G + +++V +AP Sbjct: 19899 TAENSSGTDTQKIKVVVMDAP 19919 Score = 37.5 bits (83), Expect = 4.0 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 5/125 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI---NRFQEITVKEKGTIKLVA-RVTR 858 + ++A+N+ G + T ++ E P + +T+K TI L A + Sbjct: 21273 FRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 21332 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P+P +W + + I PS+ ITQ ++ + D+G+Y A+N G Sbjct: 21333 KPLPKSSWSKAGKDIRPSD-ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEH 21391 Query: 919 ARVTI 923 +VT+ Sbjct: 21392 VKVTV 21396 Score = 37.5 bits (83), Expect = 4.0 Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582 G ++ E V G P+P +TW + I+K +Q ++ ++ +T++ I E D+G + Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 22064 Query: 583 CVAKNAAG 590 A+N G Sbjct: 22065 LTARNIVG 22072 Score = 37.5 bits (83), Expect = 4.0 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 4/88 (4%) Query: 838 RFQEITVKEKG-TIKLVARVTRNPVPSITWYR-NNEIISPSETITQNFDGENIELVITNV 895 +F++ V G T +L A V P+P+I W R + EI + +N D + L+I Sbjct: 24557 KFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK--ALLIVKD 24614 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTI 923 ID G Y ASN AG S V + Sbjct: 24615 AIRIDGGQYILRASNVAGSKSFPVNVKV 24642 Score = 37.5 bits (83), Expect = 4.0 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T + E V G P P I W R I+ S ++ + D A L++++ D G + Sbjct: 24567 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI-KNTDFKALLIVKDAIRIDGGQYIL 24625 Query: 584 VAKNAAGFAS 593 A N AG S Sbjct: 24626 RASNVAGSKS 24635 Score = 37.5 bits (83), Expect = 4.0 Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 9/141 (6%) Query: 789 ITILKPKKVKDEGVYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITV 844 +T + K+ + Y ++ A N G+ E ++V +P ++ P L ++ + I V Sbjct: 24904 VTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVV 24963 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 + G+ ++ P P ITW R + I + + +L I N D D+G Y Sbjct: 24964 RAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVN--YTQLSIDNCDRN-DAGKY 25020 Query: 905 KCVASNSAGKSSHGARVTIDV 925 NS+G S A VT+ V Sbjct: 25021 ILKLENSSGSKS--AFVTVKV 25039 Score = 37.5 bits (83), Expect = 4.0 Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 13/125 (10%) Query: 697 ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGE 750 +T +K+ E + + A+N EG A+LP + + EPP++ + K +++R Sbjct: 25992 VTKLKENTEYNFRICAINSEGVGEPATLPGSV-VAQERIEPPEIELDADLRKVVVLRASA 26050 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVK--DEGVYTLKA 807 ++ L + G P P + W K L ++ + T S T+L V D G Y L Sbjct: 26051 TLRLFVTIKGRPEPEVKW---EKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 26107 Query: 808 ENSEG 812 EN+ G Sbjct: 26108 ENNSG 26112 Score = 37.5 bits (83), Expect = 4.0 Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 V G P PEV W G K+ + ++ ++I + + + I ++++ YT+ N Sbjct: 34275 VACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGN 34334 Query: 1650 TAGTSSVEVTLKV 1662 G+ S V + + Sbjct: 34335 EFGSDSATVNIHI 34347 Score = 37.1 bits (82), Expect = 5.3 Identities = 15/50 (30%), Positives = 24/50 (48%) Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 I E++ + +KN + C G P PK+ WY+DGK++K Sbjct: 1283 ISESEAVESGFDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK 1332 Score = 37.1 bits (82), Expect = 5.3 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYYDD----DNVATLVIREVFPEDA 578 G V V G P P+I W + +T I KP+ Q+ ++ + L I + ED Sbjct: 16340 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 16399 Query: 579 GTFTCVAKNAAG 590 GT+T A N G Sbjct: 16400 GTYTVTASNRLG 16411 Score = 36.7 bits (81), Expect = 7.0 Identities = 56/273 (20%), Positives = 103/273 (37%), Gaps = 14/273 (5%) Query: 150 RVTLEKSDLFDSQEDESKPDVSQP--PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEV-- 205 ++T E+ L + E+ P P P+ + E K + E+P AK +E V Sbjct: 10569 QITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVK 10628 Query: 206 PEKINVPDDKETSQTPTSFN-KRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXX 264 EK+++ K Q K +E + + V + E + + Sbjct: 10629 EEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEP 10688 Query: 265 XXXXXXETSLVKLPKFQLKSRIKYITS-WPPESIKPLISYMGSIKQNGILSRNIKEAAKV 323 + + + +YIT P +KP+ K ++ +K+A Sbjct: 10689 TEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPE 10748 Query: 324 KK-QVFVPPKLPDVEKTELEQPLFSYEDIVE---SKKDENEIIQEKQTLEELPKEDVPEQ 379 +K V +P KL E+P +E+ + +K+++ ++ + + PK V E+ Sbjct: 10749 EKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEE 10808 Query: 380 YTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFY 412 PRK A + V EV K L P E+ + Sbjct: 10809 KVPVPRKEVAPPVR--VPEV--PKELEPEEVAF 10837 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 4/58 (6%) Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN---SKCTAI-LTV 1191 +W DGSEI+ H + D L I +C D GEY V N SK A+ LTV Sbjct: 18470 KWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 18527 Score = 36.3 bits (80), Expect = 9.2 Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 12/136 (8%) Query: 937 SYETEEGKTVILECQT--SHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXD 993 S++ EG+T + + T W+H+ ++I + H+ +I+E D Sbjct: 1465 SFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSD 1524 Query: 994 VGVIKCIVKDQ----ETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINSE-T 1044 G + +++ S +L V+ + P F+ KL++ +KE ++V Sbjct: 1525 SGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNPN 1584 Query: 1045 ADVVWERDGEIIKPKK 1060 D+VW ++ +II P K Sbjct: 1585 PDIVWLKNSDIIVPHK 1600 Score = 36.3 bits (80), Expect = 9.2 Identities = 19/81 (23%), Positives = 33/81 (40%) Query: 174 PQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSKLTPI 233 P + EE + EP EE + E++ P ++ K + PT K+ + P Sbjct: 11161 PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPA 11220 Query: 234 KIERKEMEVSTPQHAETVDGP 254 K+ +K E P + + P Sbjct: 11221 KVSKKIPEEKVPVPVQKKEAP 11241 Score = 36.3 bits (80), Expect = 9.2 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 8/107 (7%) Query: 822 VEEPT--EENAEPPLFI---NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 V EP ++ EPP I N +E +K T++L A + P P +TW + + Sbjct: 18130 VPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK 18189 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 I G +E I N E D G Y N AG + +V + Sbjct: 18190 ARIDVTPVGSKLE--IRNAAHE-DGGIYSLTVENPAGSKTVSVKVLV 18233 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G+ + + +P P W G EI DE+ +V E+D + SVL I N + Sbjct: 18449 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV--ETD--NFSSVLTIKNCLRRD 18504 Query: 705 EGTYTVVAVNREGEASLPIVLKI 727 G Y + N G ++ + L + Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTV 18527 Score = 36.3 bits (80), Expect = 9.2 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ + G P P +TW + +K + ++N + L I++ ED G + Sbjct: 23089 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLTIKDACREDVGHYVV 23147 Query: 584 VAKNAAGFASSTTELIV 600 N+AG A T +IV Sbjct: 23148 KLTNSAGEAIETLNVIV 23164 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKV--KDE 800 ++V GE+ +L A + G P P + W K+ K ++ + + T T L K D Sbjct: 25644 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 25703 Query: 801 GVYTLKAENSEGIAETSAVITV 822 G Y LK N G + V Sbjct: 25704 GQYILKLSNVGGTKSIPITVKV 25725 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS + + V G P P+I W + + + + Y AT VI+ D+G +T Sbjct: 29989 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKR-ATAVIKFCDRSDSGKYTL 30047 Query: 584 VAKNAAGF-ASSTTELIVEAP 603 KNA+G A S ++++P Sbjct: 30048 TVKNASGTKAVSVMVKVLDSP 30068 >UniRef50_Q4RE90 Cluster: Chromosome undetermined SCAF15134, whole genome shotgun sequence; n=4; Euteleostomi|Rep: Chromosome undetermined SCAF15134, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 7759 Score = 287 bits (703), Expect = 3e-75 Identities = 276/1136 (24%), Positives = 471/1136 (41%), Gaps = 54/1136 (4%) Query: 928 VTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 V F K L+ EE T LEC+ S W + +EI E++ +GR Sbjct: 10 VEFTKPLEDQ-TVEEEATATLECEVSRENADVLWLRDGQEIRKTKKYEMVIDGRKRALVI 68 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D C KD +TS L V+ EF + L D EV+EK+ A E E++ E Sbjct: 69 HDCTLDDSRTYTCGAKDFKTSCFLTVEPPHVEFTKPLHDVEVREKESARFECEVSRENIK 128 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 V W +DG I+ K KY+ +G L + + DE EY C + + +TV+E Sbjct: 129 VRWFKDGSEIR-KGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDAKTSKSSGMLTVIEEE 187 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 L + + + + E++K DA V WFK E+ + +DGK++ L I Sbjct: 188 ARFTKNLSHVEAAERDSVKLICEVSKPDADVSWFKGDEELPEGGRYEHIVDGKRRILLIR 247 Query: 1167 DCDLDDAGEYSCEVGNS-KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 D + DAGEY+C + + K + L V E + F + P V A T + ET Sbjct: 248 DLKMADAGEYNCRLSPAIKTSGSLKVNELAAEF-ISKPCSQEVVEGEKAVFTCIVSKETF 306 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 +V W+K +ED +K+ ++SD KKRTL+I+ C D+ Y ++ K++ LK V+E Sbjct: 307 EVKWFKGDKELEDGDKYQMVSDGKKRTLVIKNCELKDESGYVVIIGVTKASADLK--VLE 364 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSAS 1344 KI+ ++ G +V L + +W+ N + + + K DS S Sbjct: 365 -KLKIITPLKDTEAIEGDEVVLNCEANT-DGAKAKWLQNGETLFESSKCVMVQRDS-VFS 421 Query: 1345 LTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDS-SSINICWD 1402 L I+ V D + + L N G A ++T+ ++ P + +ID+ + + Sbjct: 422 LRIRNVHKGDEANFSISLTNQRGEQATSSCSLTVKEESLRIIVP-LEDIDTQEKKTVSFS 480 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 N N+T + ++ +E+ + + + ++ K +I++ + A A Sbjct: 481 CKVNRPNAT-LKWLKSGEEVTFNKRLVYRVDVDKHILTIKDCTLADEGEYTAIA------ 533 Query: 1462 SDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 D+ T E +I E +PT LK+ T ED E C + V WY++G+ Sbjct: 534 GDSKSTAEL--IISE----APTDFSVHLKDQTITEFEDAEFICKL-TKEKADVKWYKNGR 586 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNED 1579 +++ + +C + + + +++ PV I +D Sbjct: 587 EIREGPRYTFEKDGKMCILRIKECRPDDECEYACGVDDKRSRARLFVEEIPVEIIRPPQD 646 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 + + G + L A + EV W +N + ++ + ++ K +++ E++ Sbjct: 647 VFE--PPGSDVLFEAELNK-DRVEVKWLRNNMPVVQGDKHQMMSEGKVHRLQVCEIRPRD 703 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 +Y I A + + +E+ K + + +R+ SV P L Sbjct: 704 QGEYRIIAKDKDARAKLELAAVPQIKTTDQKYVTDVRKPITMSVPYSAYPQAQADWL--- 760 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 Y + P N + + Y ++ ++ + ++VI +N G E E + Sbjct: 761 -YD-NQSLPKENIYTSGEHTE-----YRLKDPQKSHQGHYKVIIKNTHG-----EGEAFI 808 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXX 1818 +DVP D E V +TW E +GGS + Y +E + + K W Sbjct: 809 SLDVIDVPGPVRNLQVVDTADGE-VSLTWEEPENDGGSKVTGYVLERRDVKRKTWTLVTD 867 Query: 1819 XXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 + L + Y FR+ ARN +G +D + P P N +V + Sbjct: 868 QAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNVETDKPVQAKNKFDVPDAPLNVIVGDV 927 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 + T+ W PE +GGSPIT+YI+E + W+ + I ++ E E I Sbjct: 928 SKFGCTVSWERPEWDGGSPITSYIVELRDRTSVKWSSVHVTTADELSAIINDVIENKEYI 987 Query: 1938 FRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996 FR+ AEN GV P+ SQ V++ PSPP L + N V +W TP +GG+ Sbjct: 988 FRVRAENKAGVGKPSAASQPVKIMDPIEPPSPP-LNLAWQDQNKNSVQLTWETPLSNGGS 1046 Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + GY + + W+ L + + L Y R++A N GLS+P Sbjct: 1047 MITGYIVERCEDETDKWLRCNARLCPDLFYKVSGLKYGSKYNYRVFAENAAGLSKP 1102 Score = 261 bits (639), Expect = 2e-67 Identities = 191/683 (27%), Positives = 313/683 (45%), Gaps = 33/683 (4%) Query: 1287 PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342 PP+++ RE + G+ +TL+ + P P W N +++ + DSK Sbjct: 4798 PPELILDAGMTREVKAMAGTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDSK- 4856 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L I+ D G Y L +EN G V +LDKP P + ++ S S + W Sbjct: 4857 --LEIRFCNREDCGDYTLTVENPAGSKTATCTVLVLDKPGPIQHLRVSDVRSDSAYLSWK 4914 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDI 1461 +PE+ G + I +VVE ++ +T+W+ V + +K ++ +++L +SY FR A N+ Sbjct: 4915 DPEDNGGARITNFVVEKKDTASTQWVPVCSTSKKRSMMLKHLMEGTSYSFRVAAENQYGR 4974 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTW 1515 S+ ET + K + + P K L + + E + L + GG + V + Sbjct: 4975 SEYVETPKAIKAMNP--LFPPGPPKDLHHTDVDKTE-VWLAWNWPDRNGGSEITGFLVEF 5031 Query: 1516 YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG--EVETSCVVGIQQKPVI 1573 +G+K T + ++ A N G +T+ + Q+K V Sbjct: 5032 QEEGEKEWDEWKTV-SIPESHVTGLEEGKTYRFRVRAENAIGLSRPDTTLPILCQEKLVP 5090 Query: 1574 TISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 + D+K K G + A++ GIP P W G ++ + I T ++V Sbjct: 5091 PVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPTAKWSIEGEEITSQGNTKIDTDNFSTV 5150 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689 + I E R+HS Y + SN AGT +V + + V D P+ P GPV + E++ +S+ IEW+P Sbjct: 5151 LSINECTRNHSGTYLLTVSNPAGTKTVALNVTVLDVPAAPIGPVDILEVTPDSMKIEWRP 5210 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 P DDGG +T Y +EK E + W V+ + I +L + EY+ R+ AQN +G Sbjct: 5211 PKDDGGSPITNYIVEKRESNKETWGGVSSSSL-ATSLNITRLQKGVEYVVRIRAQNKMGI 5269 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809 LES+P V + + +P + ++V + W +GGS I Y +E + + Sbjct: 5270 GAPLESKPTVAEHSF-MPPSPPGKPQPSDVSEDAVMLGWTMPLSDGGSQITGYLIERRHK 5328 Query: 1810 GKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 G KW R + L + Y+FR++A N G S P D + +T PS Sbjct: 5329 GGKWIRVNRTPCKDMRYKVLGLFEGNDYEFRVFAENIAGYSGPSPISDPCKPCRPITVPS 5388 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P N V + + +V L WT+P +GGSPI Y +E K + W K V + + + C Sbjct: 5389 PPVNPKVKDYSKTTVDLVWTKPTKDGGSPILGYSVEMKKADTEEWKK-VNLDDFI-KQCA 5446 Query: 1928 ENIKEKDEII---FRISAENTVG 1947 +K +E + FR+ A N VG Sbjct: 5447 YRVKGLEEGVTYRFRVFATNMVG 5469 Score = 228 bits (558), Expect = 1e-57 Identities = 197/842 (23%), Positives = 355/842 (42%), Gaps = 49/842 (5%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+K V E EC V+ + W G EI + + + H VL Sbjct: 101 FTKPLHDVEVREKESARFECE-VSRENIKVRWFKDGSEIRKGKKYEIIAQGRQH----VL 155 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 + E Y A + L ++ +E + + L + + +SV L Sbjct: 156 IVHKSVFDDEAEYECDAKTSKSSGMLTVI-------EEEARFTKNLSHVEAAERDSVKLI 208 Query: 756 AQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 +V P ++W K ++ P I +++ K+ D G Y + + Sbjct: 209 CEV-SKPDADVSWFKGDEELPEGGRYEHIVDGKRRILLIRDLKMADAGEYNCRLSPA--- 264 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 +TS + V E E P QE+ EK + V++ + W++ ++ + Sbjct: 265 IKTSGSLKVNELAAEFISKPCS----QEVVEGEKAVFTCI--VSKETF-EVKWFKGDKEL 317 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + DG+ LVI N + + +SG V K+S +V +EK+ + Sbjct: 318 EDGDKYQMVSDGKKRTLVIKNCELKDESG---YVVIIGVTKASADLKV---LEKLKIITP 371 Query: 934 LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 L K E EG V+L C+ + KW N + + ++Q Sbjct: 372 L-KDTEAIEGDEVVLNCEANTDGAKAKWLQNGETLFESSKCVMVQRDSVFSLRIRNVHKG 430 Query: 993 DVGVIKCIVKDQE-----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D + +Q +S L VKE I L+D + +EK ++N A + Sbjct: 431 DEANFSISLTNQRGEQATSSCSLTVKEESLRIIVPLEDIDTQEKKTVSFSCKVNRPNATL 490 Query: 1048 VWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 W + GE + K+ Y + HI L I++ ++ DEGEY+ I D TAE+ + E P Sbjct: 491 KWLKSGEEVTFNKRLVYRVDVDKHI--LTIKDCTLADEGEYTAIAGDSKSTAELIISEAP 548 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 + L++Q + + A F +LTK A V+W+K+G EI+ DGK L+I Sbjct: 549 TDFSVHLKDQTITEFEDAEFICKLTKEKADVKWYKNGREIREGPRYTFEKDGKMCILRIK 608 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 +C DD EY+C V + + A L VEE + +R P+ + P +D E+ + ++ Sbjct: 609 ECRPDDECEYACGVDDKRSRARLFVEEIPVEI-IRPPQDVFEPPGSDVLFEAELNKDRVE 667 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 V W + + +K ++S+ K L + + DQ EY + D + KL++ V Sbjct: 668 VKWLRNNMPVVQGDKHQMMSEGKVHRLQVCEIRPRDQGEYRIIAKDKDARAKLELAAV-- 725 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P+I +++Y +T+ V Y A+PQ +W+ +++ + K + Sbjct: 726 -PQIKTTDQKYVTDVRKPITMSVPYSAYPQAQADWLYDNQSLPK---ENIYTSGEHTEYR 781 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 +K + + G YK+ ++N G + +++ ++D P P +++ +++ W+EPEN Sbjct: 782 LKDPQKSHQGHYKVIIKNTHGEGEAFISLDVIDVPGPVRNLQVVDTADGEVSLTWEEPEN 841 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G S + YV+E +++ W V + ++ + ++ L+ + Y FR A N V Sbjct: 842 DGGSKVTGYVLERRDVKRKTWTLVTDQAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNV 901 Query: 1466 ET 1467 ET Sbjct: 902 ET 903 Score = 224 bits (547), Expect = 2e-56 Identities = 146/494 (29%), Positives = 228/494 (46%), Gaps = 34/494 (6%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + + A ++G P P V W K L+ D +I TK S + I + KR SS Y Sbjct: 1429 KAGSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYI 1488 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 IEA+N+ G ++ V + + DKP P I EI+ +S + W PP DDGG +T Y +E Sbjct: 1489 IEATNSCGRATATVDVNILDKPGPPAAFDIS-EITNDSCFLAWNPPRDDGGSRVTNYIVE 1547 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + D+ W +++ + TY L + EY+FRV A+N G E I+ + Sbjct: 1548 RRAADSEIWHRLSSTVKQT-TYRAAGLVKFKEYIFRVFAENQFGVGTPAEHPSIIARYPF 1606 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXX 1823 D P + +SV ++W+ +++GGSPI Y VE + E KW Sbjct: 1607 DTPGAPYNLQPSD-VAKDSVNLSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPIKD 1665 Query: 1824 A--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 +++ L+ Y+FR+ A N GT P D I + + PP P V + S Sbjct: 1666 TNYKVKGLATRKKYKFRVLAENLAGTGKPSKETDLILVKDPIDPPWPPGKPTVKDVAKTS 1725 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 L WT+PE +GG+ I +Y++E W ++V S+ E+ ++ + EK E FR+ Sbjct: 1726 CFLMWTKPEHDGGAKIDSYVVEMLKSGTVDWIRVVD-NVSLLEYFLKGLMEKQEYSFRVR 1784 Query: 1942 AENTVGVSLPTESQ------------------SVRLEKHATV------PSPPTAP--LEI 1975 A N G S P+E + + K A + PP+AP L++ Sbjct: 1785 AVNVAGESEPSEPSDPVLCKERLSTYLKCAHLNTQKPKEADITWLCVSSDPPSAPRWLDV 1844 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + + W PE DGG+P+ Y + RDV + W V V L + + L+E Sbjct: 1845 VNISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAV-DTTVKELIYTVTPLNEGS 1903 Query: 2036 TYMIRIYARNEIGL 2049 Y+ R+ A N +G+ Sbjct: 1904 LYVFRVAAENAVGV 1917 Score = 219 bits (536), Expect = 5e-55 Identities = 205/883 (23%), Positives = 359/883 (40%), Gaps = 66/883 (7%) Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT-KLKVEVVEFP 1287 + +K + E+ L + LI+ D+ YT L D KS + +++V V+ P Sbjct: 1155 FGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLENDVKSVSGEIEVNVIAAP 1214 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 D++ ++ ++ P + V + + + K + T+ Sbjct: 1215 SAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVSRKTWVKVVTGIQDQEFTV 1274 Query: 1348 KKVENTDAGIYKLRLENNCG-----HADVEMNVTI-LDKPSPPGKPNILEIDSSSINICW 1401 V ++K+ N CG + D +N++ P PP + +SSI + W Sbjct: 1275 TDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPDPPENLRWRDKSASSIFLTW 1334 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQTSIQNLKTNSSYRFRAYAVNEVD 1460 + P+ G S I Y ++ + T +W ++ +T+ + L Y +R A+N + Sbjct: 1335 EPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKVTGLTEGQWYAYRVRALNRLG 1394 Query: 1461 ISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 S + T+ + + + ++ K L +T + IEL G P+P+V W + Sbjct: 1395 ASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGKPEPRVKWTKAD 1454 Query: 1520 KKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP---- 1571 LK T Y A N G + V I KP Sbjct: 1455 LVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYIIEATNSCGRATATVDVNILDKPGPPA 1514 Query: 1572 ---VITISNEDI----KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + I+N+ G + ++E IW++ + ++ TT Sbjct: 1515 AFDISEITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQ------TTY 1568 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 +++ KE ++ A S+ + +D P P + +++++SV Sbjct: 1569 RAAGLVKFKEYIFRVFAENQFGVGTPAEHPSI-IARYPFDTPGAPYN-LQPSDVAKDSVN 1626 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + W P +DGG +T Y +E++EP++++WI+ + Y ++ L +Y FRV+A+ Sbjct: 1627 LSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPIKDTNYKVKGLATRKKYKFRVLAE 1686 Query: 1745 NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G + + E++ I++K +D P + S ++ W E +GG+ I Y Sbjct: 1687 NLAGTGKPSKETDLILVKDPID-PPWPPGKPTVKDVAKTSCFLMWTKPEHDGGAKIDSYV 1745 Query: 1804 VEIKQEGK-KW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 VE+ + G W + ++ L Y FR+ A N G S P D + + Sbjct: 1746 VEMLKSGTVDWIRVVDNVSLLEYFLKGLMEKQEYSFRVRAVNVAGESEPSEPSDPVLCKE 1805 Query: 1862 TLT--------------------------PPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 L+ PPS PR V + S LKWT PE +GGS Sbjct: 1806 RLSTYLKCAHLNTQKPKEADITWLCVSSDPPSAPRWLDVVNISRSSANLKWTVPERDGGS 1865 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-S 1954 PITNY++E + V+ K W + T + + + + E +FR++AEN VGV E + Sbjct: 1866 PITNYVVEKRDVRRKGWQAVDTTVKEL-IYTVTPLNEGSLYVFRVAAENAVGVGPFCELT 1924 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 SV + T P PP A L + V V W P+ DGG P+L Y+I ++ T W+ Sbjct: 1925 DSVLAKDTFTTPGPPYA-LAVVAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWV 1983 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + GK K+ + D+ E ++ A NE G+ P E E Sbjct: 1984 KCGKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTE 2026 Score = 213 bits (519), Expect = 6e-53 Identities = 191/717 (26%), Positives = 296/717 (41%), Gaps = 65/717 (9%) Query: 1276 TTKLKVEVVEFPPKI-VDYERE--YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KK 1330 T ++ VE ++ PP I +D + I+ G + + + P P W + K KK Sbjct: 3372 TGEVLVEDIQLPPSISIDVTADDLLCIRAGDPIRIPATIKGRPAPKVTWDFDGKAKSHKK 3431 Query: 1331 CK-HTKPSIDSK-----SASLTIKKVE-NTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 K HT P +DS+ + S+ I V T +G Y + +N G V + V +LD P P Sbjct: 3432 NKLHTLP-VDSEVESTDTTSVVIVPVSLRTHSGRYTITAKNKSGQKHVNVRVIVLDVPGP 3490 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QN 1442 P + +I S++ + W PE+ G I Y +E + I W V +Q + Sbjct: 3491 PKDLKVTDITRSTVRLIWKLPESDGGERIKSYFIEKKCITDKAWTKVNAACASQAYVVPG 3550 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIEL 1501 L Y FR A N + + TTE I P LK N+ T+ + Sbjct: 3551 LLEGQDYLFRVRAENRLGFGPFTTTTE--PAHARDPIYPPDPPTKLKVNLVTKNTVTLSW 3608 Query: 1502 TCIF--GGVPQP-----KVTWYRDGKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCI 1551 C GG P +++W GK+ +T K + ++ Sbjct: 3609 ECPKNNGGSPVTHYIIERLSWDTSGKEKETWKQCNKRDVEELSFVVEDLQEGGEYEFRIK 3668 Query: 1552 AFNDHGEVETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 A N G S G I+ + I + + G + + A + G P P + W K Sbjct: 3669 AVNAAGPSRPSTTAGPLVIKDQTFAPIIELRESMEGEEGCDVSMVAKVSGCPFPTLTWQK 3728 Query: 1609 NGN-KLEN------DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 K E D+ N + + I++ RS S+ Y++ ASN+ G+ + ++ L Sbjct: 3729 ASTAKPEEKVAILYDQHINKLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSVTKDIKLS 3788 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 V+ P P GPV E+ E + + W PP DDGG ++T Y +EK E + W+ V+D + Sbjct: 3789 VFGPPGPPVGPVKFTEVFAERIGLAWNPPTDDGGSKITSYVVEKREDNRKSWVHVSDDPK 3848 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 + + + +L EN EY FR++AQN G L S+P + VP + Sbjct: 3849 EC-AFVVTRLTENHEYEFRIMAQNKFGVGPPLLSDPEKARNLFTVPG-QCEKPTVTEVCL 3906 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA------RIQKLSINTT 1834 ES+ + W + +GGSP+ Y +E K+ K+W + L Sbjct: 3907 ESMTVNWEEPKYDGGSPVTGYFIEKKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAM 3966 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 YQFR+ A N G LP D I + PP P V+ + T SV L+W P +GG Sbjct: 3967 YQFRVIAANAAGCGLPSMPSDPILCRDPIKPPGPPTPKVI-DWTRSSVELEWIPPLLDGG 4025 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 S + + ++G TK V G +KE FR+ A N GV P Sbjct: 4026 SKVKD-----TEIRG---TKFVVAG----------LKEGGLYRFRVRAVNAAGVGEP 4064 Score = 209 bits (510), Expect = 7e-52 Identities = 181/698 (25%), Positives = 304/698 (43%), Gaps = 40/698 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNI-TKTQ 1437 P P +P +LE+ S I W+ P + G I Y++E +E W+ + + I K + Sbjct: 4595 PDAPKQPTVLEVYHDSALISWEPPAD-GGKPITGYIIERKETMANRWVRCNTERIHPKVE 4653 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE--YYK--VIKE---TKIQSPTVEKPLKN 1490 + +L Y FR A NEV + D S ++ + K ++K ++ K Sbjct: 4654 YWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPIFAKDPIVKPGPPVNLKVIDFSKESVT 4713 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYK 1549 ++ +P D IFG + + + + K+ T + E + ++ Sbjct: 4714 LSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVNHTPDSCQETKFKVINLEEGALCN--FR 4771 Query: 1550 CIAFNDHGEVETSCV---VGIQQK---PVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPP 1602 +A N GE E + + V +Q + P + + ++ K G + A I+G+P P Sbjct: 4772 VMAVNAAGESEPAYLREAVRVQDRLEPPELILDAGMTREVKAMAGTHITLMATIKGVPFP 4831 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 V W KN + E +I T + S + I+ R YT+ N AG+ + T+ V Sbjct: 4832 TVTWKKN--EAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVENPAGSKTATCTVLV 4889 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 DKP P + + ++ +S + WK P D+GG +T + +EK + + +W+ V + Sbjct: 4890 LDKPG-PIQHLRVSDVRSDSAYLSWKDPEDNGGARITNFVVEKKDTASTQWVPVCSTSKK 4948 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV-PSXXXXXXXXXXIDN 1781 + ++ L E Y FRV A+N G SE +E+ P IK + P +D Sbjct: 4949 -RSMMLKHLMEGTSYSFRVAAENQYGRSEYVET-PKAIKAMNPLFPPGPPKDLHHTDVDK 5006 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINTTYQFRIY 1840 V++ W ++NGGS I + VE ++EG+K W + + L TY+FR+ Sbjct: 5007 TEVWLAWNWPDRNGGSEITGFLVEFQEEGEKEWDEWKTVSIPESHVTGLEEGKTYRFRVR 5066 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI--T 1898 A N IG S P T+ I + L PP + + E P G P+ Sbjct: 5067 AENAIGLSRPDTTLP-ILCQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPTA 5125 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 + IE + + + TKI T S + +E S + VS P +++V Sbjct: 5126 KWSIEGEEITSQGNTKIDTDNFST-------VLSINECTRNHSGTYLLTVSNPAGTKTVA 5178 Query: 1959 LEKHAT-VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 L VP+ P P++I V + + W P+ DGG+P+ Y + R+ K W V Sbjct: 5179 LNVTVLDVPAAPIGPVDILEVTPDSMKIEWRPPKDDGGSPITNYIVEKRESNKETWGGVS 5238 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + T NI L + Y++RI A+N++G+ PLES Sbjct: 5239 SSSLAT-SLNITRLQKGVEYVVRIRAQNKMGIGAPLES 5275 Score = 200 bits (487), Expect = 4e-49 Identities = 123/406 (30%), Positives = 186/406 (45%), Gaps = 13/406 (3%) Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 + P + + D K KVGD ++ G P P + W KN +L+ D++ N+ + Sbjct: 4399 EPPTLELDIRD-KMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHL 4457 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 + I + +R HS Y + NTAG+ S T+ V D+P PEGPV+ E+ R + I W Sbjct: 4458 SLTIAKARRDHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVFNEVYRNYMVISWN 4517 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPV 1747 PPLDDGG ++ Y IEK + + + W+ V T C + KL E EY+ R++AQN Sbjct: 4518 PPLDDGGCAISNYIIEKRDTNRDLWMPV--TSSCTRTTCKVPKLIEGREYIIRIMAQNIY 4575 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G S+ LES + VP + ++S I+W P +GG PI Y +E K Sbjct: 4576 GISDPLESAETKARDIYKVPD-APKQPTVLEVYHDSALISWEP-PADGGKPITGYIIERK 4633 Query: 1808 QE-GKKW---KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 + +W + L Y+FR+ A NE+G P I + Sbjct: 4634 ETMANRWVRCNTERIHPKVEYWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPIFAKDPI 4693 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 P P N V + + SVTL W P G I Y++EF+ + W+K+ S Sbjct: 4694 VKPGPPVNLKVIDFSKESVTLSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVNHTPDSCQ 4753 Query: 1924 E--HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 E + N++E FR+ A N G S P ++VR++ P Sbjct: 4754 ETKFKVINLEEGALCNFRVMAVNAAGESEPAYLREAVRVQDRLEPP 4799 Score = 190 bits (464), Expect = 3e-46 Identities = 139/521 (26%), Positives = 220/521 (42%), Gaps = 24/521 (4%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 D + ++ G + L V + P P W + +K+ + + L ++ + Sbjct: 7233 DLRKALVLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDTLLMVEDIN 7292 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 DAG Y L LEN+ G + V +LD P PP + E + I WD P G S Sbjct: 7293 RYDAGKYVLMLENSSGSKSYTIVVKVLDSPGPPVNLTVKETTRNQAWITWDAPLIDGGSP 7352 Query: 1412 IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + YVVE + + W V KT I NL+ +Y FR A N I + ET Sbjct: 7353 VKSYVVEKRLAERKAWTCVSAECPKTSFRILNLEAGQAYCFRVLAENNYGIGEGCETPGS 7412 Query: 1471 YKVIKET-KIQSPTVEKPLKNITT----EPNED--IELTCIFGGVPQPKVTWYRDGKKLK 1523 + ++ + +K KN T +P D +T + + + W K++K Sbjct: 7413 VRASEQPGPVTDFKAQKTTKNSVTLAWKKPISDGGSYITAYVLELSEGEDKW----KQIK 7468 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISN----E 1578 K ++ A N+ GE T V + + V+ N Sbjct: 7469 KGK-----EASHTMSELTEGKEYTFRVRALNESGEGPPTELTVMAKDQFVLPDCNLSGLH 7523 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 D K G + + G+P P +W K L + + + + + I++ +R Sbjct: 7524 DNCYIVKEGSTTRINIPVIGVPYPTALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRG 7583 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 + YTI N+AG+ + +LKV +P GP+ EI+ + +T+EW PP DDGG E+ Sbjct: 7584 DADTYTINVRNSAGSKDCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAEV 7643 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 + Y +EK +N+W VA + I +L E EY+FRV A+N G E L SEP+ Sbjct: 7644 SNYIVEKRRTTDNKWATVASAIQKTSMRVI-RLQEGKEYIFRVFAENKYGVGEYLRSEPV 7702 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 + + +VP I +ES +TW + GGSPI Sbjct: 7703 IAQHPFNVPG-APAPPEIVSIRHESAILTWADPKDTGGSPI 7742 Score = 188 bits (458), Expect = 1e-45 Identities = 182/732 (24%), Positives = 281/732 (38%), Gaps = 38/732 (5%) Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTS-- 1439 PPGKP +++ SS+++ W P++ G S +I Y +EY ++ +W N QT Sbjct: 6725 PPGKPEPMDVTKSSVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESY 6784 Query: 1440 -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497 + L+ Y+FR A +++S ASE ++ VI E + +KN I + E Sbjct: 6785 VVTGLEEGQQYQFRVIAKTAINVSMASELSDPIPVIAENVPPRVDLGINMKNLIVVKAGE 6844 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAF 1553 ++ L G P PKVTW RDG L A+ ++ Y +A Sbjct: 6845 NVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVHLLELYSVTRKETGDYTILAE 6904 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N +G + V + KP S + K +V W G I K Sbjct: 6905 NINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEPPLADGGSEITNYIIEKRETS 6964 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-----YDKPS 1667 N + +++L H ++ + A N G +T V YD P Sbjct: 6965 RANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYGVGDPAMTDPVTVKNPYDVPG 7024 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 E PVI I+++S+T+ WK P +DG + Y +EK E W KV T Sbjct: 7025 PCEPPVI-TNITKDSMTVSWKAPANDGRAPILGYMVEKREATELTWAKVNRRPVIDRTIK 7083 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 +L E EY FRVIA N G + ++ + P S+ ++ Sbjct: 7084 ASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPVYPPGPPAFPKVVDSTRSSISLS 7143 Query: 1788 WFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARN 1843 W +GG II Y VE K+ E + W A + L NT YQFR+ A N Sbjct: 7144 WTKPAYDGGCEIIGYLVECKRAEAEDWTKCNVPKKLQATKFLVTSLMDNTEYQFRVSALN 7203 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES--TSRSVTLKWTEPESNGGSPITNYI 1901 +IG S P L PP + + ++ VT++ P +P + Sbjct: 7204 KIGFSEPSDVPGNHMPKDILLPPEAELDADLRKALVLRAGVTMRLYVPVRGRPAPKVTWT 7263 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +K + I T +E+I D + + EN+ G ++S ++ + K Sbjct: 7264 KVNYNLKERQGLLINTSEWDT-LLMVEDINRYDAGKYVLMLENSSG----SKSYTI-VVK 7317 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 P PP L ++ N +W P DGG+P+ Y + R + W V + Sbjct: 7318 VLDSPGPP-VNLTVKETTRNQAWITWDAPLIDGGSPVKSYVVEKRLAERKAWTCV-SAEC 7375 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXX 2081 F I +L Y R+ A N G+ E E+ PG A E+PG T+ Sbjct: 7376 PKTSFRILNLEAGQAYCFRVLAENNYGIGEGCET-------PG-SVRASEQPGPVTDFKA 7427 Query: 2082 XXXXXXXXXXXW 2093 W Sbjct: 7428 QKTTKNSVTLAW 7439 Score = 184 bits (449), Expect = 2e-44 Identities = 217/924 (23%), Positives = 371/924 (40%), Gaps = 65/924 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTV---EIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 P + ++L E I+V A T L IP T W + I + +D Sbjct: 5091 PVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPVPT--AKWSIEGEEITSQGNTKIDTDNFS 5148 Query: 1251 RTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 L I +CT + Y + + T L V V++ P + I + ++ Sbjct: 5149 TVLSINECTRNHSGTYLLTVSNPAGTKTVALNVTVLDVPAAPIG---PVDILEVTPDSMK 5205 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKP-----SIDSKSASLTIKKVENTDAGIYKLRLE 1363 ++++ P+ + + + I++K + K S S + SL I +++ + ++R + Sbjct: 5206 IEWRP-PKDDGGSPITNYIVEKRESNKETWGGVSSSSLATSLNITRLQKGVEYVVRIRAQ 5264 Query: 1364 NNCG-HADVEMNVTILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 N G A +E T+ + PSPPGKP ++ ++ + W P + G S I Y++E Sbjct: 5265 NKMGIGAPLESKPTVAEHSFMPPSPPGKPQPSDVSEDAVMLGWTMPLSDGGSQITGYLIE 5324 Query: 1419 YQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + +WI V + + L + Y FR +A N S S ++ K + Sbjct: 5325 RRH-KGGKWIRVNRTPCKDMRYKVLGLFEGNDYEFRVFAENIAGYSGPSPISDPCKPCRP 5383 Query: 1477 TKIQSPTVEKPLKN--------ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 + SP V +K+ + T+P +D + I G + K + KK+ Sbjct: 5384 ITVPSPPVNPKVKDYSKTTVDLVWTKPTKDGG-SPILGYSVEMKKADTEEWKKVNLDD-- 5440 Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE---DIKQKHK 1585 + + ++ A N G+ E+ V I I E D + + Sbjct: 5441 FIKQCAYRVKGLEEGVTYRFRVFATNMVGDGESREVPESVVAQDILIPPEIEMDATCRER 5500 Query: 1586 V----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 V G + I+ P PEVIW K LEN K I +RIKE R+ Sbjct: 5501 VTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEATRADHG 5560 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 KY ++ASN G +S +T+ V D+PS + + +++S I W+ P D+GG E+T Y Sbjct: 5561 KYILKASNEGGEASCTITVNVLDRPSHCQN-LHTTYATKDSCMINWEAPKDNGGSEITNY 5619 Query: 1702 AIEKHEPDNNRWIKVAD--VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PI 1758 +E EP W ++ +R ++ KL E EY+FRV A+N +G +E++ P+ Sbjct: 5620 IVECREPSVRMWSMISSNCTNRKIKA----KLMEGHEYLFRVCAENKMGPGPCVETKTPL 5675 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXX 1817 + L+ P I VY+ W + +GGSP + Y +E K ++ ++W+ Sbjct: 5676 LAIDPLEKPG-EPENFRVTDIGKNHVYLRWRKPDYDGGSPNLSYNLECKAKDAEEWEKLN 5734 Query: 1818 XXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 K N TY FR+ NE G S D I + + + P + Sbjct: 5735 TGVLTDTFFLADKCIENQTYTFRVQTVNEGGESTWVKLSD-ILVKEEIQKPVIDLKLAGT 5793 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + +++ P +I + K V G + G + + + D Sbjct: 5794 LTVKVGESVRMEAALRGKPQPEVKWIKD-KAV-GDNPRISYETGPDYSKFLLTKSRRTDT 5851 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 + I+A N G + SV VP P L + +G++ W PE DGG Sbjct: 5852 GKYIITATNLAGTFTAYANVSV-----LDVPG-PVRNLRLTGIGADKCRVVWDAPEDDGG 5905 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + Y + + + +W V T N+ L E + Y+ R+ A N++G + P Sbjct: 5906 CEVDSYILEKCETRRMVW-STYSASVVTPYCNVIRLVEGNEYIFRVRAENKMG-TGPATE 5963 Query: 2056 DEPFKVIPGEGSHADEEPGEQTEV 2079 +P V +P E T+V Sbjct: 5964 TKPVTVKTQFNKPGPPDPPEVTKV 5987 Score = 180 bits (438), Expect = 4e-43 Identities = 204/912 (22%), Positives = 352/912 (38%), Gaps = 66/912 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRT 1252 P ++ + + I+V A + +L E+ + L VTW + + E ++ Sbjct: 6826 PRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVHL 6885 Query: 1253 LIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP--PKIVDYEREY--RIKRGSDVT 1306 L + T + +YT + ++ +KV+V++ P P V + + R+K + Sbjct: 6886 LELYSVTRKETGDYTILAENINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEPP 6945 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 L +I+ + + +I +++K+ +++ EN Sbjct: 6946 LADGGSEITN----YIIEKRETSRANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAEN 7001 Query: 1365 NCGHADVEMN--VTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 G D M VT+ D P P P I I S+ + W P N G + I+ Y+VE Sbjct: 7002 QYGVGDPAMTDPVTVKNPYDVPGPCEPPVITNITKDSMTVSWKAPANDGRAPILGYMVEK 7061 Query: 1420 QEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E W V +I+ L + Y FR A+N+ + S+ + + Sbjct: 7062 REATELTWAKVNRRPVIDRTIKASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPV 7121 Query: 1478 KIQSP-----TVEKPLKNIT---TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 P V+ +I+ T+P D I G + + K D K K Sbjct: 7122 YPPGPPAFPKVVDSTRSSISLSWTKPAYDGGCE-IIGYLVECKRAEAEDWTKCNVPKKLQ 7180 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE-----DIKQKH 1584 + ++ A N G E S V G I + E D+++ Sbjct: 7181 ATKFLVTSLMDNTEYQ--FRVSALNKIGFSEPSDVPGNHMPKDILLPPEAELDADLRKAL 7238 Query: 1585 --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 + G + + G P P+V W K L+ + I T E +++ ++++ R + K Sbjct: 7239 VLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDTLLMVEDINRYDAGK 7298 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y + N++G+ S + +KV D P P + ++E +R I W PL DGG + Y Sbjct: 7299 YVLMLENSSGSKSYTIVVKVLDSPGPPVN-LTVKETTRNQAWITWDAPLIDGGSPVKSYV 7357 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 +EK + W V+ + ++ I L Y FRV+A+N G E E+ V Sbjct: 7358 VEKRLAERKAWTCVS-AECPKTSFRILNLEAGQAYCFRVLAENNYGIGEGCETPGSV--R 7414 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822 A + P N SV + W +GGS I Y +E+ + KWK Sbjct: 7415 ASEQPGPVTDFKAQKTTKN-SVTLAWKKPISDGGSYITAYVLELSEGEDKWKQIKKGKEA 7473 Query: 1823 XARIQKLSINTTYQFRIYARNEIG----TSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + +L+ Y FR+ A NE G T L + D+ + ++V E + Sbjct: 7474 SHTMSELTEGKEYTFRVRALNESGEGPPTELTVMAKDQFVLPDCNLSGLHDNCYIVKEGS 7533 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 + + + P P T + T+ G + V + I + + D + Sbjct: 7534 TTRINI----PVIGVPYP-TALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTY 7588 Query: 1939 RISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 I+ N+ G S+ + K P T P++ + ++ + WG P+ DGGA Sbjct: 7589 TINVRNSAG------SKDCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAE 7642 Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-----SEP 2052 + Y + R T W V T IR L E Y+ R++A N+ G+ SEP Sbjct: 7643 VSNYIVEKRRTTDNKWATVASAIQKTSMRVIR-LQEGKEYIFRVFAENKYGVGEYLRSEP 7701 Query: 2053 LESDEPFKVIPG 2064 + + PF V PG Sbjct: 7702 VIAQHPFNV-PG 7712 Score = 178 bits (434), Expect = 1e-42 Identities = 158/700 (22%), Positives = 287/700 (41%), Gaps = 41/700 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 PSPP P + + +++++ W +P G S I+ Y VE ++ DT EW V I + Sbjct: 5387 PSPPVNPKVKDYSKTTVDLVWTKPTKDGGSPILGYSVEMKKADTEEWKKVNLDDFIKQCA 5446 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 ++ L+ +YRFR +A N V ++ E E V+ + + P +E + +T Sbjct: 5447 YRVKGLEEGVTYRFRVFATNMVGDGESREVPE--SVVAQDILIPPEIEMDATCRERVTVR 5504 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCI- 1551 ++ + P+P+V W ++ L+ +K +N K I Sbjct: 5505 VGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEATRADHGKYIL 5564 Query: 1552 -AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-AVIEGIPPPEVIWYKN 1609 A N+ GE + V + +P +++ + D ++ + E+ Y Sbjct: 5565 KASNEGGEASCTITVNVLDRPSHC---QNLHTTYATKDSCMINWEAPKDNGGSEITNYIV 5621 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663 + + + +++ + T+ +L H + + A N G T + + + Sbjct: 5622 ECREPSVRMWSMISSNCTNRKIKAKLMEGHEYLFRVCAENKMGPGPCVETKTPLLAIDPL 5681 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 +KP +PE + +I + V + W+ P DGG Y +E D W K+ Sbjct: 5682 EKPGEPEN-FRVTDIGKNHVYLRWRKPDYDGGSPNLSYNLECKAKDAEEWEKLNTGVLTD 5740 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID-NE 1782 + K EN Y FRV N G S ++ I++K + P + E Sbjct: 5741 TFFLADKCIENQTYTFRVQTVNEGGESTWVKLSDILVKEEIQKPVIDLKLAGTLTVKVGE 5800 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840 SV + + + P + + ++ K G + ++ + K T ++ I Sbjct: 5801 SVRME--AALRGKPQPEVKW-IKDKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIIT 5857 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N GT Y + + + P RN ++ + + W PE +GG + +Y Sbjct: 5858 ATNLAGTFTAYANVSVLDV------PGPVRNLRLTGIGADKCRVVWDAPEDDGGCEVDSY 5911 Query: 1901 IIEFKTVKGKSWTKIVTVGGSV-HEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 I+E + W+ T SV +C + + E +E IFR+ AEN +G TE++ V Sbjct: 5912 ILEKCETRRMVWS---TYSASVVTPYCNVIRLVEGNEYIFRVRAENKMGTGPATETKPVT 5968 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 ++ P PP P E+ V + + W PE DGG + GY + ++ W+ K Sbjct: 5969 VKTQFNKPGPPDPP-EVTKVSKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNK 6027 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ + + +L NH Y R+ A NE+GL EP + P Sbjct: 6028 SPISERRMKVSNLIPNHEYQFRVKAENEVGLGEPSKPSRP 6067 Score = 175 bits (426), Expect = 1e-41 Identities = 202/870 (23%), Positives = 343/870 (39%), Gaps = 58/870 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 VTW KK+ E + + + L IR C +D +YT + + + V+ Sbjct: 4833 VTW--KKNEAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVENPAGSKTATCTVL-- 4888 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE-------WIVNSKIIKKCKHTKPSID 1339 ++D + R SDV Y ++ P D ++V K + Sbjct: 4889 ---VLDKPGPIQHLRVSDVRSDSAYLSWKDPEDNGGARITNFVVEKKDTASTQWVPVCST 4945 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI--LDKPSPPGKPNIL---EID 1393 SK S+ +K + + +++ EN G ++ VE I ++ PPG P L ++D Sbjct: 4946 SKKRSMMLKHLMEGTSYSFRVAAENQYGRSEYVETPKAIKAMNPLFPPGPPKDLHHTDVD 5005 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 + + + W+ P+ G S I ++VE+QE EW K ++ ++ + L+ +YRFR Sbjct: 5006 KTEVWLAWNWPDRNGGSEITGFLVEFQEEGEKEWDEWKTVSIPESHVTGLEEGKTYRFRV 5065 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTCIFGGVPQ 1510 A N + +S T ++ + K+ P VE K ++ I + I L I G+P Sbjct: 5066 RAENAIGLSRPDTT---LPILCQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGIPV 5122 Query: 1511 PKVTWYRDGKKLKT---AKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 P W +G+++ + K +N Y N G + V Sbjct: 5123 PTAKWSIEGEEITSQGNTKIDTDNFSTVLSINECTRNHSGTYLLTVSNPAGTKTVALNVT 5182 Query: 1567 IQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NIT 1622 + P I DI + + EW G P I K E++KE ++ Sbjct: 5183 VLDVPAAPIGPVDILEVTPDSMKIEWRPPKDDGGSPITNYI----VEKRESNKETWGGVS 5238 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYD---KPSKPEGPVIMREI 1678 + + + I L++ I A N G + +E V + P P G ++ Sbjct: 5239 SSSLATSLNITRLQKGVEYVVRIRAQNKMGIGAPLESKPTVAEHSFMPPSPPGKPQPSDV 5298 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 S ++V + W PL DGG ++T Y IE+ +WI+V Y + L E +Y Sbjct: 5299 SEDAVMLGWTMPLSDGGSQITGYLIERRH-KGGKWIRVNRTPCKDMRYKVLGLFEGNDYE 5357 Query: 1739 FRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV A+N G+S + S+P + VPS +V + W K+GGS Sbjct: 5358 FRVFAENIAGYSGPSPISDPCKPCRPITVPS-PPVNPKVKDYSKTTVDLVWTKPTKDGGS 5416 Query: 1798 PIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 PI+ Y VE+K +E KK R++ L TY+FR++A N +G Sbjct: 5417 PILGYSVEMKKADTEEWKKVNLDDFIKQCAYRVKGLEEGVTYRFRVFATNMVGDGESREV 5476 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + + L PP + E + V P I + ++ Sbjct: 5477 PESVVAQDILIPPEIEMDATCRERVTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSK 5536 Query: 1914 KIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 +I + H I+ D + + A N G + T + +V L++ PS Sbjct: 5537 RITIIQNLPVVHLRIKEATRADHGKYILKASNEGGEASCTITVNV-LDR----PS-HCQN 5590 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 L + M +W P+ +GG+ + Y + R+ + MW + N K + L Sbjct: 5591 LHTTYATKDSCMINWEAPKDNGGSEITNYIVECREPSVRMWSMISSNCTNR-KIKAK-LM 5648 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 E H Y+ R+ A N++G +E+ P I Sbjct: 5649 EGHEYLFRVCAENKMGPGPCVETKTPLLAI 5678 Score = 161 bits (392), Expect = 1e-37 Identities = 118/391 (30%), Positives = 178/391 (45%), Gaps = 25/391 (6%) Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 QKPVI + KVG+ + A + G P PEV W K+ +N + + T S Sbjct: 5782 QKPVIDLKLAGTLTV-KVGESVRMEAALRGKPQPEVKWIKDKAVGDNPR-ISYETGPDYS 5839 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 + + +R+ + KY I A+N AGT + + V D P P + + I + + W Sbjct: 5840 KFLLTKSRRTDTGKYIITATNLAGTFTAYANVSVLDVPG-PVRNLRLTGIGADKCRVVWD 5898 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPV 1747 P DDGG E+ Y +EK E W + V YC + +L E EY+FRV A+N + Sbjct: 5899 APEDDGGCEVDSYILEKCETRRMVWSTYSA--SVVTPYCNVIRLVEGNEYIFRVRAENKM 5956 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G A E++P+ +KT + P + + + + W P E +GG I Y +E K Sbjct: 5957 GTGPATETKPVTVKTQFNKPGPPDPPEVTK-VSKDEMTVVWAPPENDGGKSITGYILERK 6015 Query: 1808 QE-GKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864 ++ +W R + L N YQFR+ A NE+G P I Sbjct: 6016 EKRAVRWVPCNKSPISERRMKVSNLIPNHEYQFRVKAENEVGLGEPSKPSRPIAA----- 6070 Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-------GKSWTKIVT 1917 P VS+ST S+TL W++P +GG+PI Y ++ + + W +I T Sbjct: 6071 --KDPIGLKVSDSTKTSITLSWSKPVYDGGAPIIGYSLDLRLKSEADPEKPSEGWKRIDT 6128 Query: 1918 VGGSV-HEHCIENIKEKDEIIFRISAENTVG 1947 G V E I + EK E F++SA+N VG Sbjct: 6129 HGPLVLTEFTINQLDEKKEYEFKVSAQNQVG 6159 Score = 159 bits (387), Expect = 6e-37 Identities = 120/474 (25%), Positives = 204/474 (43%), Gaps = 22/474 (4%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + A + G P P++ W ++ ++ KE + T ++ + IK KR H YT+ A N Sbjct: 4126 IIAYVSGKPAPQISWCRDDGEVP--KEAKVETTGISNSLVIKNCKRQHQGIYTLSAKNEG 4183 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G V ++V D P P ++ +S + W P D+GG +T Y IEK E D Sbjct: 4184 GERRKAVIVEVLDVPGPVGLPFAGENLTNDSCKLTWYSPEDNGGSAITNYIIEKRESDRM 4243 Query: 1712 RWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDVPSX 1769 W V+ V R+ +Q L + Y FR+ A+N +G +E++ +V IK + VP Sbjct: 4244 GWTSVSYTVTRN--NAVVQGLLDGKGYFFRIAAENIIGMGPFIETDKMVLIKDPISVPE- 4300 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK----KWKXXXXXXXXXAR 1825 + S+ + W P + +GG+ + +Y +E + G+ + Sbjct: 4301 RPEDLIISAVTKTSISVAWMPPKYDGGAEVTEYVLESRTIGRDNFVRVGGDTKLMDRKFT 4360 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + L ++++FR+ A N++G P + + L PP+ + + + V Sbjct: 4361 LSGLKEGSSHEFRVSAVNQVGQGKPSFATKPVQCKDELEPPTLELD--IRDKMMVKVGDS 4418 Query: 1886 WTEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 T GG +P ++ + +KG + + + I + + ++ E Sbjct: 4419 CTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHL-SLTIAKARRDHSGCYCVNVE 4477 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 NT G + +V P PP P+ V N ++ SW P DGG + Y I Sbjct: 4478 NTAGSRSGACTITV-----VDRPQPPEGPVVFNEVYRNYMVISWNPPLDDGGCAISNYII 4532 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 RD + +WM V T + L E Y+IRI A+N G+S+PLES E Sbjct: 4533 EKRDTNRDLWMPVTSSCTRT-TCKVPKLIEGREYIIRIMAQNIYGISDPLESAE 4585 Score = 158 bits (384), Expect = 1e-36 Identities = 121/458 (26%), Positives = 208/458 (45%), Gaps = 30/458 (6%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIM- 1675 ++TT ++ S I I ++ + + + A N AG S+ +K+ D P P+ + Sbjct: 966 HVTTADELSAI-INDVIENKEYIFRVRAENKAGVGKPSAASQPVKIMDPIEPPSPPLNLA 1024 Query: 1676 -REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNE 1733 ++ ++ SV + W+ PL +GG +T Y +E+ E + ++W++ A + D+ Y + L Sbjct: 1025 WQDQNKNSVQLTWETPLSNGGSMITGYIVERCEDETDKWLRCNARLCPDL-FYKVSGLKY 1083 Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 +Y +RV A+N G S+ ++ D P D V + P Sbjct: 1084 GSKYNYRVFAENAAGLSKPTN---VIGPLLADDPHVGPTFDLSAFKDGLEVIV---PHPL 1137 Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA---RNEIGT-SL 1849 PI Y + KW +L+ +T+ I R + GT +L Sbjct: 1138 VIRVPITGYPTPVS----KWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTL 1193 Query: 1850 PYTSDDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 +D K G+ + PS P++F V E T + V L W P+ +GGSP+T Y +E + Sbjct: 1194 QLENDVKSVSGEIEVNVIAAPSAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKR 1253 Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHAT 1964 V K+W K+VT G E + ++ E E +F++SA N G P + V + AT Sbjct: 1254 DVSRKTWVKVVT-GIQDQEFTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPAT 1312 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024 +P PP L R ++ + +W P++DGG+ + GYNI W G + V Sbjct: 1313 IPDPP-ENLRWRDKSASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDL-VPET 1370 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 K + L+E Y R+ A N +G S+P ++ + + + Sbjct: 1371 KLKVTGLTEGQWYAYRVRALNRLGASQPCKATDEIQAV 1408 Score = 156 bits (379), Expect = 5e-36 Identities = 197/853 (23%), Positives = 341/853 (39%), Gaps = 68/853 (7%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKRGSDVTLL 1308 +L+I+ C Q YT + + + VEV++ P P + + E +D L Sbjct: 4161 SLVIKNCKRQHQGIYTLSAKNEGGERRKAVIVEVLDVPGPVGLPFAGE---NLTNDSCKL 4217 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT-----IKKVENTDAGIYKLRLE 1363 Y P+ N + + II+K + + S S ++T ++ + + +++ E Sbjct: 4218 TWYS--PEDNGGSAITNYIIEKRESDRMGWTSVSYTVTRNNAVVQGLLDGKGYFFRIAAE 4275 Query: 1364 NNCGHA---DVEMNVTILDKPSPPGKPNILEIDS---SSINICWDEPENTGNSTIIYYVV 1417 N G + + V I D S P +P L I + +SI++ W P+ G + + YV+ Sbjct: 4276 NIIGMGPFIETDKMVLIKDPISVPERPEDLIISAVTKTSISVAWMPPKYDGGAEVTEYVL 4335 Query: 1418 EYQEIDTTEWISVKNITK---TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 E + I ++ V TK + ++ LK SS+ FR AVN+V S T+ V Sbjct: 4336 ESRTIGRDNFVRVGGDTKLMDRKFTLSGLKEGSSHEFRVSAVNQVGQGKPSFATK--PVQ 4393 Query: 1475 KETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 + +++ PT+E +++ + + + L+ FGG P P ++W ++ ++LK + + Sbjct: 4394 CKDELEPPTLELDIRDKMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHST 4453 Query: 1534 XXXXXXXXXXXXXXYK---CI-AFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKV 1586 + C+ N G +C VV Q P + ++ + + V Sbjct: 4454 ASHLSLTIAKARRDHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVFNEVYRNYMV 4513 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 W G I K D +T+ + ++ +L I Sbjct: 4514 -ISWNPPLDDGGCAISNYIIEKRDT--NRDLWMPVTSSCTRTTCKVPKLIEGREYIIRIM 4570 Query: 1647 ASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 A N G S S E + +Y P P+ P ++ E+ +S I W+PP DGG +T Y Sbjct: 4571 AQNIYGISDPLESAETKARDIYKVPDAPKQPTVL-EVYHDSALISWEPPA-DGGKPITGY 4628 Query: 1702 AIEKHEPDNNRWIK--VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758 IE+ E NRW++ + VE Y + L + CEY FRV A+N VG + + S+PI Sbjct: 4629 IIERKETMANRWVRCNTERIHPKVE-YWVMDLLKGCEYEFRVSAENEVGVGDPSPPSKPI 4687 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXX 1817 K + P ESV ++W P G I Y +E ++ G ++W Sbjct: 4688 FAKDPIVKPG-PPVNLKVIDFSKESVTLSWQPPTDTGRGKIFGYLLEFQKAGEEEWSKVN 4746 Query: 1818 XX----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 ++ L FR+ A N G S P + + + L PP + Sbjct: 4747 HTPDSCQETKFKVINLEEGALCNFRVMAVNAAGESEPAYLREAVRVQDRLEPP----ELI 4802 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYI----IEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929 + +R V ++ G+ IT + F TV K V + ++ Sbjct: 4803 LDAGMTREV-------KAMAGTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDS 4855 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 E + T+ V P S++ P L + V S+ SW Sbjct: 4856 KLEIRFCNREDCGDYTLTVENPAGSKTATCTVLVLDKPGPIQHLRVSDVRSDSAYLSWKD 4915 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 PE +GGA + + + +D T W+ V ++ L E +Y R+ A N+ G Sbjct: 4916 PEDNGGARITNFVVEKKDTASTQWVPVCSTS-KKRSMMLKHLMEGTSYSFRVAAENQYGR 4974 Query: 2050 SEPLESDEPFKVI 2062 SE +E+ + K + Sbjct: 4975 SEYVETPKAIKAM 4987 Score = 151 bits (366), Expect = 2e-34 Identities = 167/718 (23%), Positives = 281/718 (39%), Gaps = 50/718 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKT 1436 PS P P I + S+ + W PE G S I Y+++ Q+ ++W+ V + T Sbjct: 3281 PSMPAAPEIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVNDPDTLHPTT 3340 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN---ITT 1493 + ++ +L+ +RFR AVN+V SD S T +V+ E P++ + + Sbjct: 3341 EFTVPSLRELKRHRFRIIAVNDVGESDPSPRTG--EVLVEDIQLPPSISIDVTADDLLCI 3398 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + I + G P PKVTW DGK K ++ Sbjct: 3399 RAGDPIRIPATIKGRPAPKVTWDFDGKAKSHKKNKLHTLPVDSEVESTDTTSVVIVPVSL 3458 Query: 1554 NDH-GEVETSCVVGIQQK----PVITISNEDIKQKHKVGDEWLVTA-VIEGIPPPE---- 1603 H G + QK VI + + KV D T +I +P + Sbjct: 3459 RTHSGRYTITAKNKSGQKHVNVRVIVLDVPGPPKDLKVTDITRSTVRLIWKLPESDGGER 3518 Query: 1604 VIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK- 1661 + Y K DK + + + + L + + A N G T + Sbjct: 3519 IKSYFIEKKCITDKAWTKVNAACASQAYVVPGLLEGQDYLFRVRAENRLGFGPFTTTTEP 3578 Query: 1662 --VYDKPSKPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN-----R 1712 D P+ P ++ +++ +VT+ W+ P ++GG +T Y IE+ D + Sbjct: 3579 AHARDPIYPPDPPTKLKVNLVTKNTVTLSWECPKNNGGSPVTHYIIERLSWDTSGKEKET 3638 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK--TALDVPSX 1769 W + D + ++ ++ L E EY FR+ A N G S + + P+VIK T + Sbjct: 3639 WKQCNKRDVEELSFVVEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVIKDQTFAPIIEL 3698 Query: 1770 XXXXXXXXXIDNESV-YITWFP----SEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA 1824 D V ++ P + + + + KV I + + Sbjct: 3699 RESMEGEEGCDVSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYD-QHINKLVNQDKCTL 3757 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 IQ+ + + + + A N +G+ T D K+++ PP P F +E + + L Sbjct: 3758 LIQQACRSDSAIYSLTASNSVGS---VTKDIKLSVFGPPGPPVGPVKF--TEVFAERIGL 3812 Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 W P +GGS IT+Y++E + KSW V+ + + E E FRI A+N Sbjct: 3813 AWNPPTDDGGSKITSYVVEKREDNRKSWVH-VSDDPKECAFVVTRLTENHEYEFRIMAQN 3871 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 GV P S + TVP P + V + +W P++DGG+P+ GY I Sbjct: 3872 KFGVGPPLLSDPEKARNLFTVPGQCEKP-TVTEVCLESMTVNWEEPKYDGGSPVTGYFIE 3930 Query: 2005 IRDVTKTMWMEVGKVDVNTL----KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ T W V + + L +++ L E Y R+ A N G P +P Sbjct: 3931 KKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAMYQFRVIAANAAGCGLPSMPSDP 3988 Score = 149 bits (362), Expect = 6e-34 Identities = 86/283 (30%), Positives = 135/283 (47%), Gaps = 5/283 (1%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQ 1836 I S + W E++GGSPI +Y VE + +K W+ + L+ + Y Sbjct: 1847 ISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAVDTTVKELIYTVTPLNEGSLYV 1906 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A N +G D + T T P P V T R V L+W P+++GG P Sbjct: 1907 FRVAAENAVGVGPFCELTDSVLAKDTFTTPGPPYALAVVAVTKRYVDLQWEAPKNDGGRP 1966 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQ 1955 I Y IE K G W K G ++ + ++ E E+ F++SAEN G+ P+E ++ Sbjct: 1967 ILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTE 2026 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + +E VPSPP L + + + +W P DGG P+ GY+I + + WM Sbjct: 2027 ILTIEDPTGVPSPPVE-LHVTGASRDFLAVAWKPPLRDGGCPISGYHIEMCEAGTEKWMR 2085 Query: 2016 VGKVDVNTLKFNIRD-LSENHTYMIRIYARNEIGLSEPLESDE 2057 V V LK+ + + + Y++R+ A N +G+SEP + E Sbjct: 2086 VNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEPSDISE 2128 Score = 147 bits (356), Expect = 3e-33 Identities = 166/687 (24%), Positives = 272/687 (39%), Gaps = 55/687 (8%) Query: 1346 TIKKVENTDAGIYKLRL--ENNCG---HADVEMNVTILDK---PSPPGKPNILEIDSSSI 1397 TIK + T+ Y+ R+ N G +D +D P PP P +++ SSI Sbjct: 7081 TIKASQLTEGAEYEFRVIAMNKAGLGKPSDASSAALAVDPVYPPGPPAFPKVVDSTRSSI 7140 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454 ++ W +P G II Y+VE + + +W K + T+ + +L N+ Y+FR Sbjct: 7141 SLSWTKPAYDGGCEIIGYLVECKRAEAEDWTKCNVPKKLQATKFLVTSLMDNTEYQFRVS 7200 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKV 1513 A+N++ S+ S+ + ++ L K + + L G P PKV Sbjct: 7201 ALNKIGFSEPSDVPGNHMPKDILLPPEAELDADLRKALVLRAGVTMRLYVPVRGRPAPKV 7260 Query: 1514 TWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 TW + LK + T E Y + N G + VV + Sbjct: 7261 TWTKVNYNLKERQGLLINTSEWDTLLMVEDINRYDAGKYVLMLENSSGSKSYTIVVKVLD 7320 Query: 1570 KPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-- 1625 P + N +K+ + W+ +I+G P V Y +L K + + E Sbjct: 7321 SPGPPV-NLTVKETTR-NQAWITWDAPLIDGGSP--VKSYVVEKRLAERKAWTCVSAECP 7376 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVI---MREISRE 1681 KTS RI L+ + + + A N G E V + S+ GPV ++ ++ Sbjct: 7377 KTS-FRILNLEAGQAYCFRVLAENNYGIGEGCETPGSV--RASEQPGPVTDFKAQKTTKN 7433 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 SVT+ WK P+ DGG +T Y +E E ++ +W ++ T + +L E EY FRV Sbjct: 7434 SVTLAWKKPISDGGSYITAYVLELSEGED-KWKQIKKGKEASHT--MSELTEGKEYTFRV 7490 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 A N G E ++ K +P +++ YI S P+I Sbjct: 7491 RALNESGEGPPTELT-VMAKDQFVLPDCNLSGL------HDNCYIVKEGSTTRINIPVIG 7543 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGT------SLPYTS 1853 + WK R ++ TT R R + T + + Sbjct: 7544 ----VPYPTALWKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTYTINVRNSAGSK 7599 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 D K ++ P E T+ +TL+W P+ +GG+ ++NYI+E + W Sbjct: 7600 DCKFSLKVVGRPGICTGPIQFDEITADGITLEWGPPKDDGGAEVSNYIVEKRRTTDNKWA 7659 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973 + + I ++E E IFR+ AEN GV S+ V + VP P AP Sbjct: 7660 TVASAIQKTSMRVIR-LQEGKEYIFRVFAENKYGVGEYLRSEPVIAQHPFNVPGAP-APP 7717 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 EI + + +W P+ GG+P+ G Sbjct: 7718 EIVSIRHESAILTWADPKDTGGSPITG 7744 Score = 146 bits (354), Expect = 6e-33 Identities = 105/375 (28%), Positives = 171/375 (45%), Gaps = 28/375 (7%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKY 1643 + G + +V A++ G P P W K GN+ E K TS + IK + R+ S Y Sbjct: 6460 RAGSKMVVEAIVAGKPAPFCKW-KQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYY 6518 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 ++ A N+ G ++ + + V D P PE P+ + E ++ T+ W P +DGG +T Y I Sbjct: 6519 SLSAENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYII 6578 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 EK + W+ V+ ++ + KL EY FRV A+N G SE + SE I+ + Sbjct: 6579 EKCDISQGDWVTVSS-SCTKTSFRMTKLIPGKEYGFRVRAENRFGISEPIYSERIIARYP 6637 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822 D PS I+ + V ++W +GGSPI Y +E K+ W Sbjct: 6638 FDPPS-EPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVK 6696 Query: 1823 XAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 + L Y FR+ A N G PP +P V++S Sbjct: 6697 ATQYTCSGLIEGLEYTFRVSALNLAGQD----------------PPGKPEPMDVTKS--- 6737 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT--VGGSVHEHCIENIKEKDEIIF 1938 SV+L W+ P+ +GGS + Y +E+ + G+ WT+ T + + + ++E + F Sbjct: 6738 SVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESYVVTGLEEGQQYQF 6797 Query: 1939 RISAENTVGVSLPTE 1953 R+ A+ + VS+ +E Sbjct: 6798 RVIAKTAINVSMASE 6812 Score = 140 bits (339), Expect = 4e-31 Identities = 108/411 (26%), Positives = 176/411 (42%), Gaps = 19/411 (4%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD--RDV 1723 PS P P I + ++ SVT+ WKPP DGG + Y I+ + + W++V D D Sbjct: 3281 PSMPAAPEIADK-TKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVNDPDTLHPT 3339 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + + L E + FR+IA N VG S+ + + ++++ PS + Sbjct: 3340 TEFTVPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVEDIQLPPSISIDVTADDLLCIR 3399 Query: 1783 SVYITWFPSEKNGG-SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 + P+ G +P + + + K + K K + ++ + + Sbjct: 3400 AGDPIRIPATIKGRPAPKVTWDFDGKAKSHK-KNKLHTLPVDSEVESTDTTSVVIVPVSL 3458 Query: 1842 RNEIG----TSLPYTSDDKITIGK-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 R G T+ + + + L P P++ V++ T +V L W PES+GG Sbjct: 3459 RTHSGRYTITAKNKSGQKHVNVRVIVLDVPGPPKDLKVTDITRSTVRLIWKLPESDGGER 3518 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQ 1955 I +Y IE K + K+WTK+ S + + + E + +FR+ AEN +G T ++ Sbjct: 3519 IKSYFIEKKCITDKAWTKVNAACAS-QAYVVPGLLEGQDYLFRVRAENRLGFGPFTTTTE 3577 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-----IRDVTK 2010 P PPT L++ +V N V SW P+ +GG+P+ Y I K Sbjct: 3578 PAHARDPIYPPDPPT-KLKVNLVTKNTVTLSWECPKNNGGSPVTHYIIERLSWDTSGKEK 3636 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 W + K DV L F + DL E Y RI A N G S P + P + Sbjct: 3637 ETWKQCNKRDVEELSFVVEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVI 3687 Score = 139 bits (336), Expect = 9e-31 Identities = 116/470 (24%), Positives = 193/470 (41%), Gaps = 17/470 (3%) Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 ++ I G P P W +L D+ +T K + + + R YT++ N Sbjct: 1138 VIRVPITGYPTPVSKWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLEN 1197 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 + S E+ + V PS P+ ++ E++R+ V + W+ P DGG LT Y +EK + Sbjct: 1198 DVKSVSGEIEVNVIAAPSAPKDFKVL-EVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVS 1256 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768 W+KV +D E + + + E EY+F+V A N G E A EP+ I + +P Sbjct: 1257 RKTWVKVVTGIQDQE-FTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPD 1315 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-XXXARI 1826 S+++TW P + +GGS I Y ++ Q G KW+ ++ Sbjct: 1316 PPENLRWRDK-SASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKV 1374 Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 L+ Y +R+ A N +G S P + D+I PP + + + K Sbjct: 1375 TGLTEGQWYAYRVRALNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKI 1434 Query: 1887 TEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 P G P + +K I T G I K D + I A N Sbjct: 1435 ELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGH-STVTIAKTKRDDSSTYIIEATN 1493 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 + G + T ++ L+K P PP A +I + ++ +W P DGG+ + Y + Sbjct: 1494 SCGRATATVDVNI-LDK----PGPPAA-FDISEITNDSCFLAWNPPRDDGGSRVTNYIVE 1547 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 R +W + V + L + Y+ R++A N+ G+ P E Sbjct: 1548 RRAADSEIWHRLSST-VKQTTYRAAGLVKFKEYIFRVFAENQFGVGTPAE 1596 Score = 137 bits (332), Expect = 3e-30 Identities = 134/567 (23%), Positives = 243/567 (42%), Gaps = 39/567 (6%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 E P E L++Q V + AT E E+++ +A V W +DG EI+ + ++ IDG+K+ L Sbjct: 7 EPPVEFTKPLEDQTVEEEATATLECEVSRENADVLWLRDGQEIRKTKKYEMVIDGRKRAL 66 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 I+DC LDD+ Y+C + K + LTVE P + FT L + + V A E+ E Sbjct: 67 VIHDCTLDDSRTYTCGAKDFKTSCFLTVEPPHVEFTKPLHD-VEVREKESARFECEVSRE 125 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV-- 1281 + V W+K S I +K+ +I+ ++ LI+ K DD+ EY C +KS+ L V Sbjct: 126 NIKVRWFKDGSEIRKGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDAKTSKSSGMLTVIE 185 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 E F + E R D L+ + P + W + + + + +D K Sbjct: 186 EEARFTKNLSHVEAAER-----DSVKLICEVSKPDADVSWFKGDEELPEGGRYEHIVDGK 240 Query: 1342 SASLTIKKVENTDAGIYKLRLENNC-GHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 L I+ ++ DAG Y RL +++N + S P ++E ++ C Sbjct: 241 RRILLIRDLKMADAGEYNCRLSPAIKTSGSLKVNELAAEFISKPCSQEVVE-GEKAVFTC 299 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--LKTNSSYRFRAYAVNE 1458 E + ++ + + D ++ V + K I+N LK S Y Sbjct: 300 IVSKE---TFEVKWFKGDKELEDGDKYQMVSDGKKRTLVIKNCELKDESGY--------- 347 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 V I ++ + KV+++ KI + PLK+ +++ L C K W ++ Sbjct: 348 VVIIGVTKASADLKVLEKLKIIT-----PLKDTEAIEGDEVVLNC-EANTDGAKAKWLQN 401 Query: 1519 GKKL-KTAKATYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVET-SCVVGIQQKPV- 1572 G+ L +++K R + N GE T SC + ++++ + Sbjct: 402 GETLFESSKCVMVQRDSVFSLRIRNVHKGDEANFSISLTNQRGEQATSSCSLTVKEESLR 461 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I + EDI + K + + + P + W K+G ++ +K ++ I Sbjct: 462 IIVPLEDIDTQEK---KTVSFSCKVNRPNATLKWLKSGEEVTFNKRLVYRVDVDKHILTI 518 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVT 1659 K+ + +YT A ++ T+ + ++ Sbjct: 519 KDCTLADEGEYTAIAGDSKSTAELIIS 545 Score = 131 bits (316), Expect = 2e-28 Identities = 129/496 (26%), Positives = 200/496 (40%), Gaps = 32/496 (6%) Query: 1643 YTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMR--EISRESVTIEWKPPLDDGGLE 1697 + + A N G + + K Y D S+P+ P M EI++ S T+ W PL DGG + Sbjct: 6319 FRVMACNKYGIGVPQDSPKSYLAVDPISEPDPPKKMDVLEITKNSATLGWLKPLRDGGAK 6378 Query: 1698 LTKYAIEKHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 + Y ++ E + ++W + V +D+ T + LNE +Y FRV A+N VG A E+ Sbjct: 6379 INGYVVDYQEEGSPEDKWTPYSVV-KDL-TIVVVGLNEGKKYKFRVAARNSVGVGLAREA 6436 Query: 1756 EPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV--EIKQEGKK 1812 E + IK L P ++ V + +P +K E ++ Sbjct: 6437 EGVFEIKERLMAPKIIMPDIVTVRAGSKMVVEAIVAGKP---APFCKWKQGNEDVLTSER 6493 Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 I+ ++ + + + A N G + ++T+ PP P Sbjct: 6494 LSVVKTLTSCTLIIKHVTRADSGYYSLSAENSTGKANQIL---RVTVMDIPGPPEAPLE- 6549 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK- 1931 ++E + TL W P+ +GGS ITNYIIE + W VTV S + K Sbjct: 6550 -ITEQDIDACTLLWNSPQEDGGSNITNYIIEKCDISQGDW---VTVSSSCTKTSFRMTKL 6605 Query: 1932 -EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 E FR+ AEN G+S P S+ + PS P L+I + + V+ SW P Sbjct: 6606 IPGKEYGFRVRAENRFGISEPIYSERIIARYPFDPPSEPQN-LQINKINKDFVILSWERP 6664 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 DGG+P+ GY I ++ +W+ + V ++ L E Y R+ A N G Sbjct: 6665 NSDGGSPITGYCIERKERNSLLWVRANESVVKATQYTCSGLIEGLEYTFRVSALNLAG-Q 6723 Query: 2051 EPLESDEPFKVIPGEGSHADEEP---GEQTEVXXXXXXXXXXXXXWLR--EHNMDADIRS 2105 +P EP V S P G + W R + MD S Sbjct: 6724 DPPGKPEPMDVTKSSVSLVWSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTES 6783 Query: 2106 YARGSLLRRDEYFFRI 2121 Y L +Y FR+ Sbjct: 6784 YVVTGLEEGQQYQFRV 6799 Score = 124 bits (299), Expect = 3e-26 Identities = 69/227 (30%), Positives = 112/227 (49%), Gaps = 9/227 (3%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 +++ +N G + S D I + P RN V ++ V+L W EPE++GGS Sbjct: 793 YKVIIKNTHGEGEAFISLDVIDV------PGPVRNLQVVDTADGEVSLTWEEPENDGGSK 846 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 +T Y++E + VK K+WT +VT E+ + ++ +FR+ A N VG E+ Sbjct: 847 VTGYVLERRDVKRKTWT-LVTDQAESPEYTVTGLQRDPMYLFRVCARNRVGHGPNVETDK 905 Query: 1957 -VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 V+ + VP P + + V SW PEWDGG+P+ Y + +RD T W Sbjct: 906 PVQAKNKFDVPDAPLNVI-VGDVSKFGCTVSWERPEWDGGSPITSYIVELRDRTSVKWSS 964 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 V + L I D+ EN Y+ R+ A N+ G+ +P + +P K++ Sbjct: 965 VHVTTADELSAIINDVIENKEYIFRVRAENKAGVGKPSAASQPVKIM 1011 Score = 124 bits (298), Expect = 4e-26 Identities = 157/703 (22%), Positives = 268/703 (38%), Gaps = 59/703 (8%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITK 1435 + +P PP K ++LEI +S + W +P G + I YVV+YQE + E W + Sbjct: 6345 ISEPDPPKKMDVLEITKNSATLGWLKPLRDGGAKINGYVVDYQEEGSPEDKWTPYSVVKD 6404 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 + L Y+FR A N V + A E ++ IKE ++ +P + P +T Sbjct: 6405 LTIVVVGLNEGKKYKFRVAARNSVGVGLAREAEGVFE-IKE-RLMAPKIIMP-DIVTVRA 6461 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXX----XXXXXXXXXXXYKCI 1551 + + I G P P W + + + T++ + Y Sbjct: 6462 GSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYYSLS 6521 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 A N G+ V + P + +I ++ L + E + Sbjct: 6522 AENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYIIEKC 6581 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPE 1670 + +++ + R+ +L + + A N G S + ++ + P P Sbjct: 6582 DISQGDWVTVSSSCTKTSFRMTKLIPGKEYGFRVRAENRFGISEPIYSERIIARYPFDPP 6641 Query: 1671 GPVIMREISR---ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 +I++ + V + W+ P DGG +T Y IE+ E ++ W++ + Y Sbjct: 6642 SEPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVKATQYT 6701 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 L E EY FRV A N G + EP+ + SV + Sbjct: 6702 CSGLIEGLEYTFRVSALNLAGQDPPGKPEPM-------------------DVTKSSVSLV 6742 Query: 1788 WFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX----XXXXXARIQKLSINTTYQFRIYAR 1842 W + +GGS +I Y +E K G+KW + L YQFR+ A+ Sbjct: 6743 WSRPKHDGGSKLIGYYMEYTKLPGEKWTRCNTNCMDIQTESYVVTGLEEGQQYQFRVIAK 6802 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPS-----QPRNFVVSESTSRSVTLKWTEPESNGGS-P 1896 I S+ D I + PP +N +V ++ +V L + E G P Sbjct: 6803 TAINVSMASELSDPIPVIAENVPPRVDLGINMKNLIVVKA-GENVFL---DAEVFGKPLP 6858 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLPTES 1954 + + + K+V H H +E ++ K+ + I AEN G T Sbjct: 6859 KVTWKRDGIPLVLAEGMKMVQ---KKHVHLLELYSVTRKETGDYTILAENINGSKYATIK 6915 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW- 2013 V L+K P PP A ++ V S+ V W P DGG+ + Y I R+ ++ W Sbjct: 6916 VKV-LDK----PGPP-ASVKTTKVFSDRVKLRWEPPLADGGSEITNYIIEKRETSRANWA 6969 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + + + ++ L E H Y R+ A N+ G+ +P +D Sbjct: 6970 LVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYGVGDPAMTD 7012 Score = 123 bits (296), Expect = 6e-26 Identities = 110/446 (24%), Positives = 181/446 (40%), Gaps = 20/446 (4%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P PE + R+ S S+ + W+PP DGG + Y I++ + ++W D+ + + Sbjct: 1314 PDPPEN-LRWRDKSASSIFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKL 1372 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + L E Y +RV A N +G S+ ++ + I + P + ++ Sbjct: 1373 K-VTGLTEGQWYAYRVRALNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAG 1431 Query: 1785 YITWFPSEKNGG-SPIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 P+E G P + + K + + + + I K + + + I A Sbjct: 1432 SKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRDDSSTYIIEA 1491 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 N G + T D I L P P F +SE T+ S L W P +GGS +TNYI Sbjct: 1492 TNSCGRATA-TVDVNI-----LDKPGPPAAFDISEITNDSCFLAWNPPRDDGGSRVTNYI 1545 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +E + + W ++ + +K K E IFR+ AEN GV P E S+ Sbjct: 1546 VERRAADSEIWHRLSSTVKQTTYRAAGLVKFK-EYIFRVFAENQFGVGTPAEHPSIIARY 1604 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 P P L+ V + V SW P+ DGG+P+ GY + + W+ K+ + Sbjct: 1605 PFDTPGAPYN-LQPSDVAKDSVNLSWYEPDEDGGSPITGYWVERYEPEHDKWIRCNKLPI 1663 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXX 2081 + ++ L+ Y R+ A N G +P S E ++ + PG+ T Sbjct: 1664 KDTNYKVKGLATRKKYKFRVLAENLAGTGKP--SKETDLILVKDPIDPPWPPGKPT---V 1718 Query: 2082 XXXXXXXXXXXWLR-EHNMDADIRSY 2106 W + EH+ A I SY Sbjct: 1719 KDVAKTSCFLMWTKPEHDGGAKIDSY 1744 Score = 121 bits (292), Expect = 2e-25 Identities = 77/282 (27%), Positives = 121/282 (42%), Gaps = 4/282 (1%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXXXARIQKLSINTTYQ 1836 I N+S ++ W P +GGS + +Y VE + + + W + R L Y Sbjct: 1521 ITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQTTYRAAGLVKFKEYI 1580 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR++A N+ G P I P P N S+ SV L W EP+ +GGSP Sbjct: 1581 FRVFAENQFGVGTP-AEHPSIIARYPFDTPGAPYNLQPSDVAKDSVNLSWYEPDEDGGSP 1639 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 IT Y +E + W + + + ++ + + + FR+ AEN G P++ Sbjct: 1640 ITGYWVERYEPEHDKWIRCNKLPIKDTNYKVKGLATRKKYKFRVLAENLAGTGKPSKETD 1699 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + L K P P ++ V W PE DGGA + Y + + W+ V Sbjct: 1700 LILVKDPIDPPWPPGKPTVKDVAKTSCFLMWTKPEHDGGAKIDSYVVEMLKSGTVDWIRV 1759 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 +V+ L++ ++ L E Y R+ A N G SEP E +P Sbjct: 1760 VD-NVSLLEYFLKGLMEKQEYSFRVRAVNVAGESEPSEPSDP 1800 Score = 121 bits (291), Expect = 3e-25 Identities = 86/321 (26%), Positives = 146/321 (45%), Gaps = 9/321 (2%) Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 D PS P ++ ISR S ++W P DGG +T Y +EK + W V +++ Sbjct: 1834 DPPSAPRWLDVVN-ISRSSANLKWTVPERDGGSPITNYVVEKRDVRRKGWQAVDTTVKEL 1892 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 Y + LNE Y+FRV A+N VG E ++ ++ K P + Sbjct: 1893 -IYTVTPLNEGSLYVFRVAAENAVGVGPFCELTDSVLAKDTFTTPG-PPYALAVVAVTKR 1950 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA--RIQKLSINTTYQFRI 1839 V + W + +GG PI+ Y +E K++ G +W R+ + T QF++ Sbjct: 1951 YVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGTEVQFQV 2010 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A NE G P + +TI PS P V+ ++ + + W P +GG PI+ Sbjct: 2011 SAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGASRDFLAVAWKPPLRDGGCPISG 2070 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCI-ENIKEKDEIIFRISAENTVGVSLPTE-SQSV 1957 Y IE + W ++ + ++ + E + + E I R+ A N+VGVS P++ S++V Sbjct: 2071 YHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEPSDISENV 2130 Query: 1958 RLEKHATVPSPPTAPLEIRMV 1978 ++ P+ L++ +V Sbjct: 2131 FAKESDCNPALDFQTLDLVVV 2151 Score = 119 bits (286), Expect = 1e-24 Identities = 110/450 (24%), Positives = 192/450 (42%), Gaps = 30/450 (6%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREI--SRESVTI 1685 R+ ++ ++ + A N AG S L + D P PV + SR+ + + Sbjct: 1996 RVTDVIEGTEVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGASRDFLAV 2055 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQ 1744 WKPPL DGG ++ Y IE E +W++V Y +++ + EY+ RV A Sbjct: 2056 AWKPPLRDGGCPISGYHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAI 2115 Query: 1745 NPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N VG SE + SE + K + P+ ++ E ++I P + SP K Sbjct: 2116 NSVGVSEPSDISENVFAKESDCNPALDFQTLDLVVVETEKLHIP-VPF-RAVPSP----K 2169 Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL-------PYTSDDK 1856 V ++GK+ K + E+ +SL T ++K Sbjct: 2170 VTWHKDGKELKADERLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKVTLENK 2229 Query: 1857 I-----TIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 + TI K + P ++ + SE T S + W P+ +GGSP+ +Y+++ + + Sbjct: 2230 LGAASGTISVKVIGLPGPCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQRREAGRR 2289 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPP 1969 ++ +++ G + ++++ E FR+ A N +G E ++ V E P PP Sbjct: 2290 TYVNMMS-GENKVSWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNPVIAEDQKHAPDPP 2348 Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029 +E S+ +W P +DGG ++GY + ++ W V L + +R Sbjct: 2349 V-DVETHNPTSSTTTLTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPVLSYTVR 2407 Query: 2030 DLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 L E +Y R+ A N G+SEP + PF Sbjct: 2408 GLKEGKSYTFRVKAENAAGVSEP-SRNTPF 2436 Score = 113 bits (272), Expect = 5e-23 Identities = 112/467 (23%), Positives = 187/467 (40%), Gaps = 43/467 (9%) Query: 1594 AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 AVI G P P+V W + G ++N + ++ + S + I E R S KY++ SN+AG Sbjct: 6203 AVIRGRPAPKVTWKRLG--VDNVIRRGHVDQVDTMSFLVIPESTREDSGKYSLHLSNSAG 6260 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 +V V +KV + D G + Y +EK E D Sbjct: 6261 EKAVFVRVKVLEN--------------------------DGGS-PILNYIVEKREVDRKT 6293 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772 W K + D ++ + + EY FRV+A N G +S + Sbjct: 6294 WTKCTE-DLKKTSFKVTNMTPGIEYYFRVMACNKYGIGVPQDSPKSYLAVDPISEPDPPK 6352 Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKL 1829 I S + W ++GG+ I Y V+ ++EG KW + L Sbjct: 6353 KMDVLEITKNSATLGWLKPLRDGGAKINGYVVDYQEEGSPEDKWTPYSVVKDLTIVVVGL 6412 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 + Y+FR+ ARN +G L ++ I + L P +V+ + ++ Sbjct: 6413 NEGKKYKFRVAARNSVGVGLAREAEGVFEIKERLMAPKIIMPDIVTVRAGSKMVVE--AI 6470 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 + +P + + V +V S I+++ D + +SAEN+ G + Sbjct: 6471 VAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSC-TLIIKHVTRADSGYYSLSAENSTGKA 6529 Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 +Q +R+ +P PP APLEI + W +P+ DGG+ + Y I D++ Sbjct: 6530 ----NQILRVTV-MDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYIIEKCDIS 6584 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + W+ V T F + L Y R+ A N G+SEP+ S+ Sbjct: 6585 QGDWVTVSSSCTKT-SFRMTKLIPGKEYGFRVRAENRFGISEPIYSE 6630 Score = 105 bits (252), Expect = 1e-20 Identities = 76/269 (28%), Positives = 120/269 (44%), Gaps = 20/269 (7%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G+ + A + G P P + W N K + D+ I ++ S++ IK +R KY Sbjct: 2855 RAGEILRLPATVTGKPYPSITWTINDAKPDKDR-VEILSEGSNSIVEIKNAQRKDCGKYH 2913 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I A N +GT ++V D P P + ++R+ + + W P DDGG +LT + +E Sbjct: 2914 ISACNPSGTKGASTRVEVVDVPG-PVTDLKPVVVTRKMIFLNWDDPEDDGGSDLTGFIVE 2972 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + + + W + + + C+ + E EYMFRVIA+N G +E PI A+ Sbjct: 2973 RRDAKMHTWRQPVET-ASSKCECV-GIMEGQEYMFRVIAKNKYGMGPPVELGPI---KAV 3027 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK---QEGKKWKXXXXXXX 1821 D S+ + W P +GGSP+I Y VE K Q+ + Sbjct: 3028 DPQERT----------KNSITLAWKPPRNDGGSPVIGYFVEKKRQDQQAFEPCNTEICPN 3077 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLP 1850 ++ L Y+FRI N IG S P Sbjct: 3078 MTMTVEGLDDAWMYEFRIKCANLIGESEP 3106 Score = 103 bits (248), Expect = 4e-20 Identities = 113/462 (24%), Positives = 182/462 (39%), Gaps = 41/462 (8%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W +G + E K+ N E+ S + +++L+ ++ I+A N AG S T Sbjct: 3629 WDTSGKEKETWKQCNKRDVEELSFV-VEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVI 3687 Query: 1666 PSKPEGPVI-MREISRESVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVAD--- 1718 + P+I +RE + G LT +P+ I Sbjct: 3688 KDQTFAPIIELRESMEGEEGCDVSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYDQHIN 3747 Query: 1719 --VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 V++D T IQ+ + ++ + A N VG ++ I + + P Sbjct: 3748 KLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSV----TKDIKL-SVFGPPGPPVGPVKF 3802 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI-QKLSINTT 1834 + E + + W P +GGS I Y VE +++ +K W A + +L+ N Sbjct: 3803 TEVFAERIGLAWNPPTDDGGSKITSYVVEKREDNRKSWVHVSDDPKECAFVVTRLTENHE 3862 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y+FRI A+N+ G P SD + T P Q V+E S+T+ W EP+ +GG Sbjct: 3863 YEFRIMAQNKFGVGPPLLSDPE-KARNLFTVPGQCEKPTVTEVCLESMTVNWEEPKYDGG 3921 Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 SP+T Y IE K K WT++ + + + + E FR+ A N G L Sbjct: 3922 SPVTGYFIEKKETTSKRWTRVNRDPIRALPLGNNWDVTGLLEGAMYQFRVIAANAAGCGL 3981 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 P+ L + P P P I S++ + W P DGG+ Sbjct: 3982 PSMPSDPILCRDPIKPPGPPTPKVIDWTRSSVEL-EWIPPLLDGGS-------------- 4026 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 +V ++ KF + L E Y R+ A N G+ EP Sbjct: 4027 ----KVKDTEIRGTKFVVAGLKEGGLYRFRVRAVNAAGVGEP 4064 Score = 99 bits (238), Expect = 7e-19 Identities = 103/474 (21%), Positives = 192/474 (40%), Gaps = 31/474 (6%) Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPS--KPEGPVIMR- 1676 + T K + + L + + A N G E+T V K + P P + Sbjct: 1885 VDTTVKELIYTVTPLNEGSLYVFRVAAENAVGVGPFCELTDSVLAKDTFTTPGPPYALAV 1944 Query: 1677 -EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 +++ V ++W+ P +DGG + +Y+IEK E RW+K Y + + E Sbjct: 1945 VAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKCGKTSGPDCKYRVTDVIEGT 2004 Query: 1736 EYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 E F+V A+N G E +E + I+ VPS + + + W P ++ Sbjct: 2005 EVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVELHVTGA-SRDFLAVAWKPPLRD 2063 Query: 1795 GGSPIIDYKVEIKQEG-KKWKXXXX--XXXXXARIQKLSI-NTTYQFRIYARNEIGTSLP 1850 GG PI Y +E+ + G +KW R+++ + Y R+ A N +G S P Sbjct: 2064 GGCPISGYHIEMCEAGTEKWMRVNSRPVKELKYRVEEGVVPEKEYILRVRAINSVGVSEP 2123 Query: 1851 YTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPES-------NGGSPITNY 1900 + + ++ P+ Q + VV E+ + + + S +G + Sbjct: 2124 SDISENVFAKESDCNPALDFQTLDLVVVETEKLHIPVPFRAVPSPKVTWHKDGKELKADE 2183 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 + F + H +++ D ++++ EN +G + T S V Sbjct: 2184 RLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKVTLENKLGAASGTISVKV-- 2241 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 +P P + + + SW P++DGG+P++ Y + R+ + ++ + Sbjct: 2242 ---IGLPG-PCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQRREAGRRTYVNMMSG 2297 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 + N + + ++DL Y R+ A N+IG E +E P VI + HA + P Sbjct: 2298 E-NKVSWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNP--VIAEDQKHAPDPP 2348 Score = 99.5 bits (237), Expect = 9e-19 Identities = 78/300 (26%), Positives = 126/300 (42%), Gaps = 25/300 (8%) Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXX 1819 + LDVP I + + W E +GG + Y +E K E ++ W Sbjct: 5872 SVLDVPGPVRNLRLTG-IGADKCRVVWDAPEDDGGCEVDSYILE-KCETRRMVWSTYSAS 5929 Query: 1820 XXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + +L Y FR+ A N++GT P T +T+ P P V++ + Sbjct: 5930 VVTPYCNVIRLVEGNEYIFRVRAENKMGTG-PATETKPVTVKTQFNKPGPPDPPEVTKVS 5988 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 +T+ W PE++GG IT YI+E K + W S + N+ E F Sbjct: 5989 KDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNKSPISERRMKVSNLIPNHEYQF 6048 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGA 1996 R+ AEN VG+ P++ P P+ +++ S + SW P +DGGA Sbjct: 6049 RVKAENEVGLGEPSKPSR---------PIAAKDPIGLKVSDSTKTSITLSWSKPVYDGGA 6099 Query: 1997 PLLGYNIAIR-----DVTKTM--WMEVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIG 2048 P++GY++ +R D K W + L +F I L E Y ++ A+N++G Sbjct: 6100 PIIGYSLDLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKEYEFKVSAQNQVG 6159 Score = 95.5 bits (227), Expect = 1e-17 Identities = 69/285 (24%), Positives = 126/285 (44%), Gaps = 20/285 (7%) Query: 1599 IPPPEVIWYKNGNKLENDKEYNITT------------KEKTSV-IRIKELKRSHSSKYTI 1645 +P P+V W+K+G +L+ D+ + + KE TS + + + + +Y + Sbjct: 2165 VPSPKVTWHKDGKELKADERLSFSIPHSCMCPNLFNRKEYTSCHLEVDSSLHADAGQYKV 2224 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 N G +S +++KV P P ++ EI++ S + W PP DGG + Y +++ Sbjct: 2225 TLENKLGAASGTISVKVIGLPG-PCKDILASEITKHSCKVSWDPPDYDGGSPVIHYVLQR 2283 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764 E ++ + + V ++ ++ L EY FRV A N +G E +E P++ + Sbjct: 2284 REAGRRTYVNMMSGENKV-SWTVKDLIPGGEYYFRVQAVNKIGGGEFIELRNPVIAEDQK 2342 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK--XXXXXXX 1821 P + + +TW P +GG I+ Y +E++Q+G KW+ Sbjct: 2343 HAPDPPVDVETHNPTSSTTT-LTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPV 2401 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 ++ L +Y FR+ A N G S P + I + PP Sbjct: 2402 LSYTVRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPP 2446 Score = 92.3 bits (219), Expect = 1e-16 Identities = 87/329 (26%), Positives = 143/329 (43%), Gaps = 28/329 (8%) Query: 1156 IDGKKQKLKIYDCDLDDAGE--YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 I+GK+ K+ C+ GE Y E N A T+ +P N R + + Sbjct: 1278 IEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPA--TIPDPPENLRWR------DKSASS 1329 Query: 1214 AYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVL 1270 +LT E P D + Y T+K+ D+ T L + TE Y Sbjct: 1330 IFLTWEPPKYDGGSGIRGYNIDRCQRGTDKWEPCGDLVPETKLKVTGLTEGQWYAYRVRA 1389 Query: 1271 LD-------AKSTTKLKVEVVEFPPKI-VDYE--REYRIKRGSDVTLLVDYQAFPQPNDE 1320 L+ K+T +++ + PP+I +D + K GS + L + + P+P + Sbjct: 1390 LNRLGASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGKPEPRVK 1449 Query: 1321 WIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 W ++K + SID+K +++TI K + D+ Y + N+CG A ++V IL Sbjct: 1450 WTKADLVLKP--DDRISIDTKPGHSTVTIAKTKRDDSSTYIIEATNSCGRATATVDVNIL 1507 Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 DKP PP +I EI + S + W+ P + G S + Y+VE + D+ W + + K T Sbjct: 1508 DKPGPPAAFDISEITNDSCFLAWNPPRDDGGSRVTNYIVERRAADSEIWHRLSSTVKQTT 1567 Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASE 1466 L Y FR +A N+ + +E Sbjct: 1568 YRAAGLVKFKEYIFRVFAENQFGVGTPAE 1596 Score = 89.8 bits (213), Expect = 7e-16 Identities = 72/279 (25%), Positives = 127/279 (45%), Gaps = 15/279 (5%) Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELK 1636 ED +++ K G+E T E P PE ++ N++ +I + + S + +K+ Sbjct: 2524 EDKEKEKKEGEEEKKT---EKTPEPEAEVEESDYPTINER-LSINNRHRGVSSVVVKDSA 2579 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 R+ Y ++ N G++S + V + P PE P I +I+ S+ + WK P +D G Sbjct: 2580 RADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQI-EDITAHSMLVTWKEP-NDNGS 2637 Query: 1697 ELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754 + Y +E+ E +++RW +V D+ D + ++ L E Y+FRV A+N G + ++ Sbjct: 2638 PIMGYWVERREINSSRWTRVNRDIVPDTQLN-VEGLLEGLTYIFRVAAENQAGPGKFSVP 2696 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW 1813 S+P ++ + +P D+ S+ + W P NGG I+ Y V+ G K W Sbjct: 2697 SDPKTAQSPV-LPPGPPVARVAATTDH-SIDVEWDPPVDNGGGEILGYHVDKAMAGTKDW 2754 Query: 1814 KXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 + + YQ R+ A N G P Sbjct: 2755 SRSTERPWKNRAFTVYGVREGAKYQIRVIACNAAGEGTP 2793 Score = 85.8 bits (203), Expect = 1e-14 Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 2/167 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ GS + + P P +W ++ + + S +L IK V D+G Y Sbjct: 6459 VRAGSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYY 6518 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417 L EN+ G A+ + VT++D P PP P I E D + + W+ P+ G S I Y++ Sbjct: 6519 SLSAENSTGKANQILRVTVMDIPGPPEAPLEITEQDIDACTLLWNSPQEDGGSNITNYII 6578 Query: 1418 EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 E +I +W++V + TKT + L Y FR A N IS+ Sbjct: 6579 EKCDISQGDWVTVSSSCTKTSFRMTKLIPGKEYGFRVRAENRFGISE 6625 Score = 83.0 bits (196), Expect = 8e-14 Identities = 93/425 (21%), Positives = 184/425 (43%), Gaps = 32/425 (7%) Query: 1126 FEIELTKGDALVRWFK---DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + +E+ K D W K D Q + ++ +G + +++ ++ GE S EV Sbjct: 5421 YSVEMKKADT-EEWKKVNLDDFIKQCAYRVKGLEEGVTYRFRVFATNMVGDGE-SREVPE 5478 Query: 1183 SKCTA-ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 S IL E ++ T R + V N + ++ E +V W K+++V+E++++ Sbjct: 5479 SVVAQDILIPPEIEMDATCRERVTVRVGHNVNIIGYIKARPEP-EVIWSKEETVLENSKR 5537 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRI 1299 T+I ++ L I++ T D +Y + +++ + V V++ P + Y Sbjct: 5538 ITIIQNLPVVHLRIKEATRADHGKYILKASNEGGEASCTITVNVLDRPSHCQNLHTTYAT 5597 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKSASLTIK-KVENTD 1354 K + +++++A P+ N + + I+ +C+ I S + IK K+ Sbjct: 5598 KD----SCMINWEA-PKDNGGSEITNYIV-ECREPSVRMWSMISSNCTNRKIKAKLMEGH 5651 Query: 1355 AGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEIDSSSINICWDEPENTG 1408 ++++ EN G VE + L+KP P + +I + + + W +P+ G Sbjct: 5652 EYLFRVCAENKMGPGPCVETKTPLLAIDPLEKPGEPENFRVTDIGKNHVYLRWRKPDYDG 5711 Query: 1409 NSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 S + Y +E + D EW ++ +T T N +Y FR VNE S Sbjct: 5712 GSPNLSYNLECKAKDAEEWEKLNTGVLTDTFFLADKCIENQTYTFRVQTVNE---GGEST 5768 Query: 1467 TTEYYKVIKETKIQSPTVEKPLK-NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + ++ + +IQ P ++ L +T + E + + G PQP+V W +D Sbjct: 5769 WVKLSDILVKEEIQKPVIDLKLAGTLTVKVGESVRMEAALRGKPQPEVKWIKDKAVGDNP 5828 Query: 1526 KATYE 1530 + +YE Sbjct: 5829 RISYE 5833 Score = 78.2 bits (184), Expect = 2e-12 Identities = 68/256 (26%), Positives = 117/256 (45%), Gaps = 22/256 (8%) Query: 1226 DVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 +V W K K+V ++ + D K L + T+ + T L T V V+ Sbjct: 5815 EVKWIKDKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIITATNLAGTFTAYANVSVL 5874 Query: 1285 EFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 + P + R R+ G+D +V + A P+ + V+S I++KC+ + + SA Sbjct: 5875 DVPGPV----RNLRLTGIGADKCRVV-WDA-PEDDGGCEVDSYILEKCETRRMVWSTYSA 5928 Query: 1344 SLT------IKKVENTDAGIYKLRLENNCGH--ADVEMNVTI---LDKPSPPGKPNILEI 1392 S+ I+ VE + I+++R EN G A VT+ +KP PP P + ++ Sbjct: 5929 SVVTPYCNVIRLVEGNEY-IFRVRAENKMGTGPATETKPVTVKTQFNKPGPPDPPEVTKV 5987 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYR 1450 + + W PEN G +I Y++E +E W+ I++ + + NL N Y+ Sbjct: 5988 SKDEMTVVWAPPENDGGKSITGYILERKEKRAVRWVPCNKSPISERRMKVSNLIPNHEYQ 6047 Query: 1451 FRAYAVNEVDISDASE 1466 FR A NEV + + S+ Sbjct: 6048 FRVKAENEVGLGEPSK 6063 Score = 76.6 bits (180), Expect = 7e-12 Identities = 39/118 (33%), Positives = 65/118 (55%), Gaps = 3/118 (2%) Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 +S+ +K D G+Y +++EN+ G A V +L+ P P KP I +I + S+ + W Sbjct: 2571 SSVVVKDSARADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWK 2630 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 EP + G S I+ Y VE +EI+++ W V + TQ +++ L +Y FR A N+ Sbjct: 2631 EPNDNG-SPIMGYWVERREINSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQ 2687 Score = 76.6 bits (180), Expect = 7e-12 Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 8/193 (4%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 L PP P + + T+ S+ + W EP N GSPI Y +E + + WT++ Sbjct: 2606 LEPPEAPEKPQIEDITAHSMLVTWKEPNDN-GSPIMGYWVERREINSSRWTRVNRDIVPD 2664 Query: 1923 HEHCIENIKEKDEIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 + +E + E IFR++AEN G S+P++ ++ + P PP A + Sbjct: 2665 TQLNVEGLLEGLTYIFRVAAENQAGPGKFSVPSDPKTA--QSPVLPPGPPVA--RVAATT 2720 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 + + W P +GG +LGY++ W + F + + E Y I Sbjct: 2721 DHSIDVEWDPPVDNGGGEILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQI 2780 Query: 2040 RIYARNEIGLSEP 2052 R+ A N G P Sbjct: 2781 RVIACNAAGEGTP 2793 Score = 75.8 bits (178), Expect = 1e-11 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 4/171 (2%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G + ++ P P W + + K K S SL IK + GIY Sbjct: 4118 VHAGGTIRIIAYVSGKPAPQISWCRDDGEVPK--EAKVETTGISNSLVIKNCKRQHQGIY 4175 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVV 1417 L +N G + V +LD P P G P E + + S + W PE+ G S I Y++ Sbjct: 4176 TLSAKNEGGERRKAVIVEVLDVPGPVGLPFAGENLTNDSCKLTWYSPEDNGGSAITNYII 4235 Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 E +E D W SV +T+ +Q L Y FR A N + + ET Sbjct: 4236 EKRESDRMGWTSVSYTVTRNNAVVQGLLDGKGYFFRIAAENIIGMGPFIET 4286 Score = 72.9 bits (171), Expect = 9e-11 Identities = 49/175 (28%), Positives = 78/175 (44%), Gaps = 15/175 (8%) Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 T + + L W +PE +GGS +T +I+E + K +W + V S E C+ I E E + Sbjct: 2947 TRKMIFLNWDDPEDDGGSDLTGFIVERRDAKMHTWRQPVETASSKCE-CV-GIMEGQEYM 3004 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 FR+ A+N G+ P E ++ A P T N + +W P DGG+P Sbjct: 3005 FRVIAKNKYGMGPPVELGPIK----AVDPQERT---------KNSITLAWKPPRNDGGSP 3051 Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 ++GY + + + + + + L + Y RI N IG SEP Sbjct: 3052 VIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEP 3106 Score = 68.5 bits (160), Expect = 2e-09 Identities = 52/214 (24%), Positives = 86/214 (40%), Gaps = 7/214 (3%) Query: 1287 PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 PP++ ++ + +K G +V L + P P W + + + K Sbjct: 6825 PPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQKKHVH 6884 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L + V + G Y + EN G + V +LDKP PP ++ S + + W+ Sbjct: 6885 LLELYSVTRKETGDYTILAENINGSKYATIKVKVLDKPGPPASVKTTKVFSDRVKLRWEP 6944 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITK--TQTSIQNLKTNSSYRFRAYAVNEVD 1460 P G S I Y++E +E W V NI T S++ L Y+FR A N+ Sbjct: 6945 PLADGGSEITNYIIEKRETSRANWALVTSNIHGHITDCSVEKLIEGHEYQFRVSAENQYG 7004 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 + D + T+ V + P + NIT + Sbjct: 7005 VGDPA-MTDPVTVKNPYDVPGPCEPPVITNITKD 7037 Score = 67.3 bits (157), Expect = 4e-09 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 2/180 (1%) Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 + + V +P P +W K + + + + S L + D G Y L+LE Sbjct: 1137 LVIRVPITGYPTPVSKWTFGEKELTTTDERVRLTAKSTFTELIVTPSVRPDKGTYTLQLE 1196 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 N+ E+ V ++ PS P +LE+ +++ W+ P++ G S + Y VE +++ Sbjct: 1197 NDVKSVSGEIEVNVIAAPSAPKDFKVLEVTRQHVHLSWETPDHDGGSPLTGYQVEKRDVS 1256 Query: 1424 TTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 W+ V I + ++ ++ Y F+ A N+ + + E + I P Sbjct: 1257 RKTWVKVVTGIQDQEFTVTDVIEGKEYVFKVSACNKCGPGEPAYIDEPVNISSPATIPDP 1316 Score = 67.3 bits (157), Expect = 4e-09 Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 5/146 (3%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 PSPP + ++ + + W P G I Y +E E T +W+ V + + + + Sbjct: 2037 PSPPVELHVTGASRDFLAVAWKPPLRDGGCPISGYHIEMCEAGTEKWMRVNSRPVKELKY 2096 Query: 1439 SIQN-LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 ++ + Y R A+N V +S+ S+ +E V + +P ++ ++ E Sbjct: 2097 RVEEGVVPEKEYILRVRAINSVGVSEPSDISE--NVFAKESDCNPALDFQTLDLVVVETE 2154 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK 1523 + + F VP PKVTW++DGK+LK Sbjct: 2155 KLHIPVPFRAVPSPKVTWHKDGKELK 2180 Score = 65.7 bits (153), Expect = 1e-08 Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 S L + + DAG YK+ LEN G A ++V ++ P P EI S + W Sbjct: 2206 SCHLEVDSSLHADAGQYKVTLENKLGAASGTISVKVIGLPGPCKDILASEITKHSCKVSW 2265 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 D P+ G S +I+YV++ +E +++ + K ++++L Y FR AVN++ Sbjct: 2266 DPPDYDGGSPVIHYVLQRREAGRRTYVNMMSGENKVSWTVKDLIPGGEYYFRVQAVNKI 2324 Score = 64.9 bits (151), Expect = 2e-08 Identities = 48/191 (25%), Positives = 77/191 (40%), Gaps = 5/191 (2%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTY 1835 I S+ +TW NG SPI+ Y VE ++ +W + ++ L TY Sbjct: 2620 ITAHSMLVTWKEPNDNG-SPIMGYWVERREINSSRWTRVNRDIVPDTQLNVEGLLEGLTY 2678 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 FR+ A N+ G D T + PP P V + +T S+ ++W P NGG Sbjct: 2679 IFRVAAENQAGPGKFSVPSDPKTAQSPVLPPGPPVARVAA-TTDHSIDVEWDPPVDNGGG 2737 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 I Y ++ K W++ + ++E + R+ A N G P ++ Sbjct: 2738 EILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQIRVIACNAAGEGTPGFTE 2797 Query: 1956 SVRLEKHATVP 1966 SV + A P Sbjct: 2798 SVFVRNPAGQP 2808 Score = 64.9 bits (151), Expect = 2e-08 Identities = 38/96 (39%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 L+ T PS P AP EI + V SW PE DGG+P+ GY I I+D K+ W+ V Sbjct: 3274 LDNGGTPPSMPAAP-EIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVRVND 3332 Query: 2019 VDV--NTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 D T +F + L E + RI A N++G S+P Sbjct: 3333 PDTLHPTTEFTVPSLRELKRHRFRIIAVNDVGESDP 3368 Score = 62.5 bits (145), Expect = 1e-07 Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 6/115 (5%) Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 TPPS P +++ T SVTL W PE +GGSPI YII+ + W + V ++H Sbjct: 3279 TPPSMPAAPEIADKTKHSVTLSWKPPERDGGSPIKGYIIQIQDEGKSDWVR-VNDPDTLH 3337 Query: 1924 ---EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 E + +++E FRI A N VG S P+ L + + PP+ +++ Sbjct: 3338 PTTEFTVPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVE--DIQLPPSISIDV 3390 Score = 60.1 bits (139), Expect = 7e-07 Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 9/220 (4%) Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 NDHG +C V + + P + E + + LVT ++ Y + Sbjct: 2592 NDHGSASAACEVNVLEPPE---APEKPQIEDITAHSMLVTWKEPNDNGSPIMGYWVERRE 2648 Query: 1614 ENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKP 1669 N + ++ + + ++ L + + + A N AG SV K P P Sbjct: 2649 INSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQAGPGKFSVPSDPKTAQSPVLP 2708 Query: 1670 EGPVIMREISR--ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 GP + R + S+ +EW PP+D+GG E+ Y ++K W + + + Sbjct: 2709 PGPPVARVAATTDHSIDVEWDPPVDNGGGEILGYHVDKAMAGTKDWSRSTERPWKNRAFT 2768 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 + + E +Y RVIA N G +E + ++ P Sbjct: 2769 VYGVREGAKYQIRVIACNAAGEGTPGFTESVFVRNPAGQP 2808 Score = 60.1 bits (139), Expect = 7e-07 Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 9/136 (6%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I+N + KD + ISA N G T+ S R+E VP P T L+ +V ++ + Sbjct: 2901 IKNAQRKDCGKYHISACNPSG----TKGASTRVEV-VDVPGPVT-DLKPVVVTRKMIFLN 2954 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W PE DGG+ L G+ + RD W + V+ + K + E YM R+ A+N+ Sbjct: 2955 WDDPEDDGGSDLTGFIVERRDAKMHTWRQ--PVETASSKCECVGIMEGQEYMFRVIAKNK 3012 Query: 2047 IGLSEPLESDEPFKVI 2062 G+ P+E P K + Sbjct: 3013 YGMGPPVELG-PIKAV 3027 Score = 58.4 bits (135), Expect = 2e-06 Identities = 43/160 (26%), Positives = 72/160 (45%), Gaps = 7/160 (4%) Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQV-I 738 V + D + ++ +K+ + V AVN+ G+ K E EPP + + Sbjct: 4346 VRVGGDTKLMDRKFTLSGLKEGSSHEFRVSAVNQVGQGKPSFATKPVQCKDELEPPTLEL 4405 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPK 795 + M+V+ G+S LS + G P P I+W KNN+ +K + S S+TI K + Sbjct: 4406 DIRDKMMVKVGDSCTLSGRFGGRPTPAISWTKNNEELKGDEQINLHSTASHLSLTIAKAR 4465 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + G Y + EN+ G + ITV + + P +F Sbjct: 4466 R-DHSGCYCVNVENTAGSRSGACTITVVDRPQPPEGPVVF 4504 Score = 57.2 bits (132), Expect = 5e-06 Identities = 43/190 (22%), Positives = 77/190 (40%), Gaps = 16/190 (8%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQ 1836 + + +++ W E +GGS + + VE +++ K W+ + Y Sbjct: 2946 VTRKMIFLNWDDPEDDGGSDLTGFIVE-RRDAKMHTWRQPVETASSKCECVGIMEGQEYM 3004 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A+N+ G P + +G Q R T S+TL W P ++GGSP Sbjct: 3005 FRVIAKNKYGMGPP------VELGPIKAVDPQER-------TKNSITLAWKPPRNDGGSP 3051 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + Y +E K +++ T +E + + FRI N +G S P+ + Sbjct: 3052 VIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEPSIPLT 3111 Query: 1957 VRLEKHATVP 1966 V ++ P Sbjct: 3112 VVIQDDEVAP 3121 Score = 56.8 bits (131), Expect = 6e-06 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 3/139 (2%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 P PP SS+ + W P G I+ Y++E Q+ +W + + Sbjct: 2345 PDPPVDVETHNPTSSTTTLTWKPPMYDGGCKIMGYILEMQQKGDDKWERCNDFLVPVLSY 2404 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497 +++ LK SY FR A N +S+ S T + K + + L++ + + Sbjct: 2405 TVRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGY 2464 Query: 1498 DIELTCIFGGVPQPKVTWY 1516 +I L G P P++TWY Sbjct: 2465 EICLDANISGSPYPQITWY 2483 Score = 56.8 bits (131), Expect = 6e-06 Identities = 87/404 (21%), Positives = 142/404 (35%), Gaps = 39/404 (9%) Query: 1283 VVEFPPKIVDYEREYRIKRGSDVT------LLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 V+ FP +I E + +K G + L P P+ W +N K + Sbjct: 2832 VLVFPTEIPFVELDLSVKNGVTIRAGEILRLPATVTGKPYPSITWTINDAKPDKDRVEIL 2891 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 S S S + IK + D G Y + N G V ++D P P + + Sbjct: 2892 SEGSNSI-VEIKNAQRKDCGKYHISACNPSGTKGASTRVEVVDVPGPVTDLKPVVVTRKM 2950 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 I + WD+PE+ G S + ++VE ++ W ++ + Y FR A Sbjct: 2951 IFLNWDDPEDDGGSDLTGFIVERRDAKMHTWRQPVETASSKCECVGIMEGQEYMFRVIAK 3010 Query: 1457 NEVDISDASETTEYYKV--IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 N+ + E V + TK KP +N P + G + K Sbjct: 3011 NKYGMGPPVELGPIKAVDPQERTKNSITLAWKPPRNDGGSP--------VIGYFVEKK-- 3060 Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--CVVGIQQKPV 1572 +D + + ++ N GE E S V IQ V Sbjct: 3061 -RQDQQAFEPCNTEICPNMTMTVEGLDDAWMYEFRIKCANLIGESEPSIPLTVVIQDDEV 3119 Query: 1573 ITISNEDIKQKHKVGDEWLV--------TAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + E KH GD +V A + G+P P++ W K+ +E E + Sbjct: 3120 ---APEIHMLKHFKGDSIVVKKGDAIEIPADVLGLPIPKIEWSKDDVIIEKPTENLLMET 3176 Query: 1625 EK------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 E T+ + I + R YT+ ASN G++ +++ V Sbjct: 3177 EVTGRMNCTTKLSIPSVNRRDRGSYTVSASNNMGSAKHTISVMV 3220 Score = 56.8 bits (131), Expect = 6e-06 Identities = 68/318 (21%), Positives = 133/318 (41%), Gaps = 29/318 (9%) Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSK-CTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 +GKK K ++ A S VG ++ + ++E + + +P+ + V A + Sbjct: 6414 EGKKYKFRV-------AARNSVGVGLAREAEGVFEIKERLMAPKIIMPDIVTVRAGSKMV 6466 Query: 1216 LTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA- 1273 + + + W + + +E+ +++ + TLII+ T D Y+ ++ Sbjct: 6467 VEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHVTRADSGYYSLSAENST 6526 Query: 1274 -KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 K+ L+V V++ P E I D+ PQ + + + II+KC Sbjct: 6527 GKANQILRVTVMDIPGPP---EAPLEITE-QDIDACTLLWNSPQEDGGSNITNYIIEKCD 6582 Query: 1333 HTKPSIDSKSASLT------IKKVENTDAGIYKLRLENNCGHADVEMNVTIL-----DKP 1381 ++ + S+S T K + + G +++R EN G ++ + I+ D P Sbjct: 6583 ISQGDWVTVSSSCTKTSFRMTKLIPGKEYG-FRVRAENRFGISEPIYSERIIARYPFDPP 6641 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTS 1439 S P I +I+ + + W+ P + G S I Y +E +E ++ W+ + TQ + Sbjct: 6642 SEPQNLQINKINKDFVILSWERPNSDGGSPITGYCIERKERNSLLWVRANESVVKATQYT 6701 Query: 1440 IQNLKTNSSYRFRAYAVN 1457 L Y FR A+N Sbjct: 6702 CSGLIEGLEYTFRVSALN 6719 Score = 53.6 bits (123), Expect = 6e-05 Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 3/103 (2%) Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPL--EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005 V + + S V PP AP +I + ++ ++ +W P D G+P++GY + Sbjct: 2588 VKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWKEPN-DNGSPIMGYWVER 2646 Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 R++ + W V + V + N+ L E TY+ R+ A N+ G Sbjct: 2647 REINSSRWTRVNRDIVPDTQLNVEGLLEGLTYIFRVAAENQAG 2689 Score = 52.4 bits (120), Expect = 1e-04 Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 8/177 (4%) Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV-EMNV 1375 P ++V + +++ K T+ + ++++ EN G E+ Sbjct: 1866 PITNYVVEKRDVRRKGWQAVDTTVKELIYTVTPLNEGSLYVFRVAAENAVGVGPFCELTD 1925 Query: 1376 TILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++L K P PP ++ + +++ W+ P+N G I+ Y +E +E T W+ Sbjct: 1926 SVLAKDTFTTPGPPYALAVVAVTKRYVDLQWEAPKNDGGRPILRYSIEKKEKLGTRWVKC 1985 Query: 1431 KNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 + + + ++ + +F+ A NE I SE TE + T + SP VE Sbjct: 1986 GKTSGPDCKYRVTDVIEGTEVQFQVSAENEAGIGHPSEPTEILTIEDPTGVPSPPVE 2042 Score = 51.6 bits (118), Expect = 2e-04 Identities = 43/152 (28%), Positives = 76/152 (50%), Gaps = 21/152 (13%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP---EGPVIMR--EISRESVT 1684 +++ L +H ++ ++A N EV L KPS+P + P+ ++ + ++ S+T Sbjct: 6035 MKVSNLIPNHEYQFRVKAEN-------EVGLGEPSKPSRPIAAKDPIGLKVSDSTKTSIT 6087 Query: 1685 IEWKPPLDDGGLELTKYAIE---KHEPDNNR----WIKVADVDRDVET-YCIQKLNENCE 1736 + W P+ DGG + Y+++ K E D + W ++ V T + I +L+E E Sbjct: 6088 LSWSKPVYDGGAPIIGYSLDLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKE 6147 Query: 1737 YMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767 Y F+V AQN VG+ A E + K L+ P Sbjct: 6148 YEFKVSAQNQVGWGRHAYLKEAVSPKEILEAP 6179 Score = 51.2 bits (117), Expect = 3e-04 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 11/137 (8%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVL--KIKTGE-KEPPQV---IEPLKSMIVRQ 748 LK+T + + Q Y V A+NR G AS P +I+ + KEPP++ + L + + Sbjct: 1372 LKVTGLTEGQWYAYRVRALNRLG-ASQPCKATDEIQAVDPKEPPEIQLDAKLLAGLTAKA 1430 Query: 749 GESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G + L A+V G P P + W K + KP + + ++TI K K+ D Y + Sbjct: 1431 GSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKR-DDSSTYII 1489 Query: 806 KAENSEGIAETSAVITV 822 +A NS G A + + + Sbjct: 1490 EATNSCGRATATVDVNI 1506 Score = 49.6 bits (113), Expect = 0.001 Identities = 39/137 (28%), Positives = 65/137 (47%), Gaps = 8/137 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLK--IKTGEK-EPPQVIEPL---KSMIVRQG 749 K+ N+++ + V+AVN GE+ P L+ ++ ++ EPP++I + + G Sbjct: 4758 KVINLEEGALCNFRVMAVNAAGESE-PAYLREAVRVQDRLEPPELILDAGMTREVKAMAG 4816 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + L A + G P PT+TW KN V T S ++ +D G YTL EN Sbjct: 4817 THITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTDSKLEIRFCNREDCGDYTLTVEN 4876 Query: 810 SEGI-AETSAVITVEEP 825 G T V+ +++P Sbjct: 4877 PAGSKTATCTVLVLDKP 4893 Score = 49.2 bits (112), Expect = 0.001 Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 12/126 (9%) Query: 716 EGEASLPIVLKIKTGEKEPP-QVIEPLK--SMIVRQGESVILSAQVVGNPRPTITWCKNN 772 E E S+P+ + I+ E P +++ K S++V++G+++ + A V+G P P I W K++ Sbjct: 3103 ESEPSIPLTVVIQDDEVAPEIHMLKHFKGDSIVVKKGDAIEIPADVLGLPIPKIEWSKDD 3162 Query: 773 ----KPVKAL--PTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAE-TSAVITVE 823 KP + L T+ G + T L V +D G YT+ A N+ G A+ T +V+ + Sbjct: 3163 VIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRRDRGSYTVSASNNMGSAKHTISVMVLG 3222 Query: 824 EPTEEN 829 E N Sbjct: 3223 ELKRTN 3228 Score = 49.2 bits (112), Expect = 0.001 Identities = 24/82 (29%), Positives = 48/82 (58%), Gaps = 2/82 (2%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDE 800 + ++V G ++ + A V G P P I+WC+++ V K ++ G ++S+ ++K K + + Sbjct: 4114 EKIVVHAGGTIRIIAYVSGKPAPQISWCRDDGEVPKEAKVETTGISNSL-VIKNCKRQHQ 4172 Query: 801 GVYTLKAENSEGIAETSAVITV 822 G+YTL A+N G + ++ V Sbjct: 4173 GIYTLSAKNEGGERRKAVIVEV 4194 Score = 47.6 bits (108), Expect = 0.004 Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 8/109 (7%) Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPT 765 T + V+ E S PI + E PP+V I ++V+ GE+V L A+V G P P Sbjct: 6803 TAINVSMASELSDPIPV---IAENVPPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPK 6859 Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEG 812 +TW ++ P+ + +L+ V K+ G YT+ AEN G Sbjct: 6860 VTWKRDGIPLVLAEGMKMVQKKHVHLLELYSVTRKETGDYTILAENING 6908 Score = 46.0 bits (104), Expect = 0.011 Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 EN G S I+ Y+VE +E+D W +++ KT + N+ Y FR A N+ I Sbjct: 6272 ENDGGSPILNYIVEKREVDRKTWTKCTEDLKKTSFKVTNMTPGIEYYFRVMACNKYGIGV 6331 Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 ++ + Y + P + + IT Sbjct: 6332 PQDSPKSYLAVDPISEPDPPKKMDVLEIT 6360 Score = 45.6 bits (103), Expect = 0.015 Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 2/75 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNP 860 + +KAEN+ G++E S + + P +F++ + + VK I L A ++ +P Sbjct: 2417 FRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGYEICLDANISGSP 2476 Query: 861 VPSITWYRNNEIISP 875 P ITWY NN++I P Sbjct: 2477 YPQITWYWNNQVIQP 2491 Score = 45.2 bits (102), Expect = 0.020 Identities = 25/86 (29%), Positives = 42/86 (48%) Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 +E ++ S+T+ WKPP +DGG + Y +EK D + T ++ L++ Sbjct: 3030 QERTKNSITLAWKPPRNDGGSPVIGYFVEKKRQDQQAFEPCNTEICPNMTMTVEGLDDAW 3089 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIK 1761 Y FR+ N +G SE +VI+ Sbjct: 3090 MYEFRIKCANLIGESEPSIPLTVVIQ 3115 Score = 45.2 bits (102), Expect = 0.020 Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 3/121 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A NS G+ V E E P + + +TV+ + + A V P P Sbjct: 6420 FRVAARNSVGVGLAREAEGVFEIKERLMAPKIIMPDI--VTVRAGSKMVVEAIVAGKPAP 6477 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 W + NE + SE ++ + L+I +V + DSG Y A NS GK++ RVT Sbjct: 6478 FCKWKQGNEDVLTSERLSVVKTLTSCTLIIKHV-TRADSGYYSLSAENSTGKANQILRVT 6536 Query: 923 I 923 + Sbjct: 6537 V 6537 Score = 44.4 bits (100), Expect = 0.035 Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 1/121 (0%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A N G + S + +E P L ++ ++ VK + L R P P Sbjct: 4372 FRVSAVNQVGQGKPSFATKPVQCKDELEPPTLELDIRDKMMVKVGDSCTLSGRFGGRPTP 4431 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +I+W +NNE + E I + ++ L I + SG Y N+AG S +T Sbjct: 4432 AISWTKNNEELKGDEQINLHSTASHLSLTIAKARRD-HSGCYCVNVENTAGSRSGACTIT 4490 Query: 923 I 923 + Sbjct: 4491 V 4491 Score = 44.0 bits (99), Expect = 0.046 Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 7/124 (5%) Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVG 760 Q T+ V VN GE++ + I E+ VI+ LK ++ V+ GESV + A + G Sbjct: 5752 QTYTFRVQTVNEGGESTWVKLSDILVKEEIQKPVID-LKLAGTLTVKVGESVRMEAALRG 5810 Query: 761 NPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P+P + W K +K V P S G +S +L + D G Y + A N G A Sbjct: 5811 KPQPEVKWIK-DKAVGDNPRISYETGPDYSKFLLTKSRRTDTGKYIITATNLAGTFTAYA 5869 Query: 819 VITV 822 ++V Sbjct: 5870 NVSV 5873 Score = 43.6 bits (98), Expect = 0.061 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 4/96 (4%) Query: 746 VRQGESVILSAQVVGNPRPTITWCKNN-KPVK-ALPTKSDGDTHSITILKPKKVKDEGVY 803 +R GE + L A V G P P+ITW N+ KP K + S+G ++SI +K + KD G Y Sbjct: 2854 IRAGEILRLPATVTGKPYPSITWTINDAKPDKDRVEILSEG-SNSIVEIKNAQRKDCGKY 2912 Query: 804 TLKAENSEGIAETSA-VITVEEPTEENAEPPLFINR 838 + A N G S V V+ P P+ + R Sbjct: 2913 HISACNPSGTKGASTRVEVVDVPGPVTDLKPVVVTR 2948 Score = 43.6 bits (98), Expect = 0.061 Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 9/129 (6%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGTIKLVARVTRNP 860 + +K N G +E S +TV +E A + F+ I VK+ I++ A V P Sbjct: 3093 FRIKCANLIGESEPSIPLTVVIQDDEVAPEIHMLKHFKGDSIVVKKGDAIEIPADVLGLP 3152 Query: 861 VPSITWYRNNEII-SPSETITQNFD--GE---NIELVITNVDSEIDSGDYKCVASNSAGK 914 +P I W +++ II P+E + + G +L I +V+ D G Y ASN+ G Sbjct: 3153 IPKIEWSKDDVIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRR-DRGSYTVSASNNMGS 3211 Query: 915 SSHGARVTI 923 + H V + Sbjct: 3212 AKHTISVMV 3220 Score = 43.6 bits (98), Expect = 0.061 Identities = 34/138 (24%), Positives = 60/138 (43%), Gaps = 8/138 (5%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI---NRFQEITVKEKGTIKLVARVTRN 859 + + A N+ G +E A + ++ EPP I +E+ I L+A + Sbjct: 4770 FRVMAVNAAGESEP-AYLREAVRVQDRLEPPELILDAGMTREVKAMAGTHITLMATIKGV 4828 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P++TW +N + P I + +E+ N + D GDY N AG + Sbjct: 4829 PFPTVTWKKNEAEVPPRADIETSQTDSKLEIRFCNRE---DCGDYTLTVENPAGSKTATC 4885 Query: 920 RVTIDVEKVTFVKHLQKS 937 V + ++K ++HL+ S Sbjct: 4886 TVLV-LDKPGPIQHLRVS 4902 Score = 43.2 bits (97), Expect = 0.081 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P++I P + VR G +++ A V G P P W + N+ V S T + L Sbjct: 6449 PKIIMP-DIVTVRAGSKMVVEAIVAGKPAPFCKWKQGNEDVLTSERLSVVKTLTSCTLII 6507 Query: 795 KKVK--DEGVYTLKAENSEGIAETSAVITV 822 K V D G Y+L AENS G A +TV Sbjct: 6508 KHVTRADSGYYSLSAENSTGKANQILRVTV 6537 Score = 42.7 bits (96), Expect = 0.11 Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 E DGG+P+L Y + R+V + W + + D+ F + +++ Y R+ A N+ G+ Sbjct: 6272 ENDGGSPILNYIVEKREVDRKTWTKCTE-DLKKTSFKVTNMTPGIEYYFRVMACNKYGIG 6330 Query: 2051 EPLESDEPFKVI 2062 P +S + + + Sbjct: 6331 VPQDSPKSYLAV 6342 Score = 42.3 bits (95), Expect = 0.14 Identities = 20/81 (24%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS ++ +V+G P P++ W + ++KP + + +T+ I + +D+ T+ Sbjct: 1431 GSKIELPAEVKGKPEPRVKWTKADLVLKPDDRISIDTKPGH-STVTIAKTKRDDSSTYII 1489 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 A N+ G A++T ++ I++ P Sbjct: 1490 EATNSCGRATATVDVNILDKP 1510 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 9/107 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-- 561 ++Q+ API +E +G V +V G P P +TW ++ + KP + + YD Sbjct: 3688 KDQTFAPI-IELRESMEGEEGCDVSMVAKVSGCPFPTLTW-QKASTAKPEEKVAILYDQH 3745 Query: 562 -----DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + TL+I++ D+ ++ A N+ G + +L V P Sbjct: 3746 INKLVNQDKCTLLIQQACRSDSAIYSLTASNSVGSVTKDIKLSVFGP 3792 Score = 42.3 bits (95), Expect = 0.14 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 4/81 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ + ++G P P +TW + A + P D + D + L IR ED G +T Sbjct: 4816 GTHITLMATIKGVPFPTVTWKKNEAEVPPRADIETSQTD---SKLEIRFCNREDCGDYTL 4872 Query: 584 VAKNAAGFASST-TELIVEAP 603 +N AG ++T T L+++ P Sbjct: 4873 TVENPAGSKTATCTVLVLDKP 4893 Score = 42.3 bits (95), Expect = 0.14 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 10/126 (7%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRN 859 + ++AEN+ G++ + + +E PP+ + + I VK TI+L A + Sbjct: 5063 FRVRAENAIGLSRPDTTLPIL--CQEKLVPPVVEVDVKLIEGIIVKAGTTIRLPAIMRGI 5120 Query: 860 PVPSITW-YRNNEIISPSETITQNFDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917 PVP+ W EI S T D +N V++ N + SG Y SN AG + Sbjct: 5121 PVPTAKWSIEGEEITSQGNT---KIDTDNFSTVLSINECTRNHSGTYLLTVSNPAGTKTV 5177 Query: 918 GARVTI 923 VT+ Sbjct: 5178 ALNVTV 5183 Score = 41.1 bits (92), Expect = 0.33 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 16/145 (11%) Query: 697 ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKE-PPQVIEPLKS---MIVRQGES 751 + ++++ + + ++AVN GE+ P ++ + + PP + + + + +R G+ Sbjct: 3344 VPSLRELKRHRFRIIAVNDVGESDPSPRTGEVLVEDIQLPPSISIDVTADDLLCIRAGDP 3403 Query: 752 VILSAQVVGNPRPTITW-----CKNNKPVK--ALPTKSD---GDTHSITILKPKKVKDEG 801 + + A + G P P +TW K++K K LP S+ DT S+ I+ G Sbjct: 3404 IRIPATIKGRPAPKVTWDFDGKAKSHKKNKLHTLPVDSEVESTDTTSVVIVPVSLRTHSG 3463 Query: 802 VYTLKAENSEGIAETSA-VITVEEP 825 YT+ A+N G + VI ++ P Sbjct: 3464 RYTITAKNKSGQKHVNVRVIVLDVP 3488 Score = 40.3 bits (90), Expect = 0.57 Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKV 797 K++++R G ++ L V G P P +TW K N +K L S+ DT + +++ Sbjct: 7236 KALVLRAGVTMRLYVPVRGRPAPKVTWTKVNYNLKERQGLLINTSEWDT--LLMVEDINR 7293 Query: 798 KDEGVYTLKAENSEGIAETSAVITV 822 D G Y L ENS G + V+ V Sbjct: 7294 YDAGKYVLMLENSSGSKSYTIVVKV 7318 Score = 39.9 bits (89), Expect = 0.75 Identities = 57/268 (21%), Positives = 111/268 (41%), Gaps = 22/268 (8%) Query: 1482 PTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXX 1534 P VE KPL++ T E L C V W RDG++++ K YE + Sbjct: 8 PPVEFTKPLEDQTVEEEATATLECEVSR-ENADVLWLRDGQEIRKTKK-YEMVIDGRKRA 65 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVT 1593 Y C A + +TSC + ++ V T D++ + K + Sbjct: 66 LVIHDCTLDDSRTYTCGA----KDFKTSCFLTVEPPHVEFTKPLHDVEVREKESARFECE 121 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 E I +V W+K+G+++ K+Y I + + V+ + + ++Y +A T+ + Sbjct: 122 VSRENI---KVRWFKDGSEIRKGKKYEIIAQGRQHVLIVHKSVFDDEAEYECDA-KTSKS 177 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 S + ++ + +K V E R+SV + + D +++ + ++ P+ R+ Sbjct: 178 SGMLTVIEEEARFTKNLSHVEAAE--RDSVKLICEVSKPDA--DVSWFKGDEELPEGGRY 233 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRV 1741 + D R + K+ + EY R+ Sbjct: 234 EHIVDGKRRILLIRDLKMADAGEYNCRL 261 Score = 39.5 bits (88), Expect = 0.99 Identities = 39/162 (24%), Positives = 71/162 (43%), Gaps = 12/162 (7%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI--EPLKSMI-VRQGES 751 + +K+ + T+ V A N G E S +PP+V L+S + V++G Sbjct: 2406 VRGLKEGKSYTFRVKAENAAGVSEPSRNTPFIKALDAVDPPKVFLSGSLQSGLNVKRGYE 2465 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD---THSITILKPKKVKDEGVYTLKAE 808 + L A + G+P P ITW NN+ ++ P + + + I + +K K+ +K + Sbjct: 2466 ICLDANISGSPYPQITWYWNNQVIQPEPLRKRPERPLKKKVEIKEEEKTKEVTEEEMKED 2525 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 + E E+ TE+ EP + T+ E+ +I Sbjct: 2526 KEKEKKEGEE----EKKTEKTPEPEAEVEESDYPTINERLSI 2563 Score = 39.5 bits (88), Expect = 0.99 Identities = 39/175 (22%), Positives = 70/175 (40%), Gaps = 16/175 (9%) Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 ++++ EN G + + P G + + +SI + W +P G + II Y + Sbjct: 6048 FRVKAENEVGLGEPSKPSRPIAAKDPIGL-KVSDSTKTSITLSWSKPVYDGGAPIIGYSL 6106 Query: 1418 EYQ---EIDTTE----WISVKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 + + E D + W + + T+ +I L Y F+ A N+V + Sbjct: 6107 DLRLKSEADPEKPSEGWKRIDTHGPLVLTEFTINQLDEKKEYEFKVSAQNQVGWGRHAYL 6166 Query: 1468 TEYYKVIKETKIQSPTVEKPL---KNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 E V + +++P ++ K + I L + G P PKVTW R G Sbjct: 6167 KE--AVSPKEILEAPEIDLDASLRKGLAVRAGCPIRLFAVIRGRPAPKVTWKRLG 6219 Score = 38.7 bits (86), Expect = 1.7 Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 21/159 (13%) Query: 700 VKKFQEG---TYTVVAVNREGEA-----SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 V+ QEG + + AVN G + + P+V+K +T +IE +SM +G Sbjct: 3654 VEDLQEGGEYEFRIKAVNAAGPSRPSTTAGPLVIKDQTFAP----IIELRESMEGEEGCD 3709 Query: 752 VILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSI------TILKPKKVK-DEGV 802 V + A+V G P PT+TW K + KP + + D + + T+L + + D + Sbjct: 3710 VSMVAKVSGCPFPTLTWQKASTAKPEEKVAILYDQHINKLVNQDKCTLLIQQACRSDSAI 3769 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 Y+L A NS G ++V P P F F E Sbjct: 3770 YSLTASNSVGSVTKDIKLSVFGPPGPPVGPVKFTEVFAE 3808 Score = 38.7 bits (86), Expect = 1.7 Identities = 23/104 (22%), Positives = 51/104 (49%), Gaps = 4/104 (3%) Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 + +TV+ + ++ + P P + W + ++ S+ IT + + L I + Sbjct: 5499 ERVTVRVGHNVNIIGYIKARPEPEVIWSKEETVLENSKRITIIQNLPVVHLRIKEA-TRA 5557 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942 D G Y ASN G++S +T++V ++ + ++L +Y T++ Sbjct: 5558 DHGKYILKASNEGGEAS--CTITVNVLDRPSHCQNLHTTYATKD 5599 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 8/118 (6%) Query: 628 ILEGIPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 I E +PP V G ++ L+ + P P + W G +V E + + Sbjct: 6820 IAENVPPRVDLGINMKNLIVVKAGENVFLDAEVFGKPLPKVTWKRDGIPLVLAEGMKMVQ 6879 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 + +H+ L++ +V + + G YT++A N G I +K+ + PP ++ K Sbjct: 6880 KKHVHL----LELYSVTRKETGDYTILAENINGSKYATIKVKV-LDKPGPPASVKTTK 6932 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +T++ ++L A VT P PSITW N+ + + +G N + I N + D Sbjct: 2852 VTIRAGEILRLPATVTGKPYPSITW-TINDAKPDKDRVEILSEGSNSIVEIKNAQRK-DC 2909 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G Y A N +G RV + Sbjct: 2910 GKYHISACNPSGTKGASTRVEV 2931 Score = 37.9 bits (84), Expect = 3.0 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 8/133 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP----LKSMIVRQGESV 752 +T +++ + + V A N G + L I EK P V+E ++ +IV+ G ++ Sbjct: 5052 VTGLEEGKTYRFRVRAENAIGLSRPDTTLPILCQEKLVPPVVEVDVKLIEGIIVKAGTTI 5111 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKV--KDEGVYTLKAEN 809 L A + G P PT W + + + TK D D S T+L + G Y L N Sbjct: 5112 RLPAIMRGIPVPTAKWSIEGEEITSQGNTKIDTDNFS-TVLSINECTRNHSGTYLLTVSN 5170 Query: 810 SEGIAETSAVITV 822 G + +TV Sbjct: 5171 PAGTKTVALNVTV 5183 Score = 37.5 bits (83), Expect = 4.0 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 5/124 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRN 859 Y ++A N G ++ T E + EPP L +T K I+L A V Sbjct: 1385 YRVRALNRLGASQPCKA-TDEIQAVDPKEPPEIQLDAKLLAGLTAKAGSKIELPAEVKGK 1443 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P + W + + ++ P + I+ + + + I + DS Y A+NS G+++ Sbjct: 1444 PEPRVKWTKADLVLKPDDRISIDTKPGHSTVTIAKTKRD-DSSTYIIEATNSCGRATATV 1502 Query: 920 RVTI 923 V I Sbjct: 1503 DVNI 1506 Score = 37.5 bits (83), Expect = 4.0 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 ++I V GTI+++A V+ P P I+W R++ + P E + G + LVI N + Sbjct: 4114 EKIVVHAGGTIRIIAYVSGKPAPQISWCRDDGEV-PKEAKVET-TGISNSLVIKNCKRQ- 4170 Query: 900 DSGDYKCVASNSAGK 914 G Y A N G+ Sbjct: 4171 HQGIYTLSAKNEGGE 4185 Score = 37.5 bits (83), Expect = 4.0 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 7/98 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G+ I L + IP P W +GEEI N + D + +VL I + Sbjct: 5105 VKAGTTIRLPAIMRGIPVPTAKWSIEGEEITSQGNTKI----DTDNFSTVLSINECTRNH 5160 Query: 705 EGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIE 739 GTY + N G ++ + VL + P ++E Sbjct: 5161 SGTYLLTVSNPAGTKTVALNVTVLDVPAAPIGPVDILE 5198 Score = 37.1 bits (82), Expect = 5.3 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 5/93 (5%) Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL--FINRFQEITVK 845 S ++K D GVY +K EN G A + + V EP E +P + +T K Sbjct: 2571 SSVVVKDSARADHGVYMVKVENDHGSASAACEVNVLEPPEAPEKPQIEDITAHSMLVTWK 2630 Query: 846 E---KGTIKLVARVTRNPVPSITWYRNNEIISP 875 E G+ + V R + S W R N I P Sbjct: 2631 EPNDNGSPIMGYWVERREINSSRWTRVNRDIVP 2663 Score = 37.1 bits (82), Expect = 5.3 Identities = 41/195 (21%), Positives = 84/195 (43%), Gaps = 14/195 (7%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287 W K +++ DT + + + TL+IR C D YT + ++ + K + V Sbjct: 7551 WKKGDTMLGDTGRMCVEASQGITTLLIRDCQRGDADTYTINVRNSAGSKDCKFSLKVVGR 7610 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK---PSIDS--KS 1342 P I ++ +TL P+ + V++ I++K + T ++ S + Sbjct: 7611 PGICTGPIQFDEITADGITL---EWGPPKDDGGAEVSNYIVEKRRTTDNKWATVASAIQK 7667 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSI 1397 S+ + +++ I+++ EN G + + ++ + P P P I+ I S Sbjct: 7668 TSMRVIRLQEGKEYIFRVFAENKYGVGEYLRSEPVIAQHPFNVPGAPAPPEIVSIRHESA 7727 Query: 1398 NICWDEPENTGNSTI 1412 + W +P++TG S I Sbjct: 7728 ILTWADPKDTGGSPI 7742 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 506 QSMAPI-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +S P+ F + L + + +T EC+V + W R I+ ++ ++M D Sbjct: 5 RSEPPVEFTKPLEDQTVEEEATATLECEVSR-ENADVLWLRDGQEIRKTKKYEMVIDGRK 63 Query: 565 VATLVIREVFPEDAGTFTCVAKN 587 A LVI + +D+ T+TC AK+ Sbjct: 64 RA-LVIHDCTLDDSRTYTCGAKD 85 Score = 36.7 bits (81), Expect = 7.0 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 5/95 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAII-KPSQDFQMYYDDD---NVAT-LVIREVFPEDA 578 G ++ V G P P+I W + II KP+++ M + N T L I V D Sbjct: 3139 GDAIEIPADVLGLPIPKIEWSKDDVIIEKPTENLLMETEVTGRMNCTTKLSIPSVNRRDR 3198 Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 G++T A N G A T ++V L +T+ Sbjct: 3199 GSYTVSASNNMGSAKHTISVMVLGELKRTNDCLTI 3233 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 7/108 (6%) Query: 1357 IYKLRLENNCGHA--DVEMNVTILDKPS-PPGKP--NILEIDSSSINICWDEPENTGNST 1411 I+++ EN G V + P PPG P + SI++ WD P + G Sbjct: 2679 IFRVAAENQAGPGKFSVPSDPKTAQSPVLPPGPPVARVAATTDHSIDVEWDPPVDNGGGE 2738 Query: 1412 IIYYVVEYQEIDTTEWI-SVKNITKTQT-SIQNLKTNSSYRFRAYAVN 1457 I+ Y V+ T +W S + K + ++ ++ + Y+ R A N Sbjct: 2739 ILGYHVDKAMAGTKDWSRSTERPWKNRAFTVYGVREGAKYQIRVIACN 2786 >UniRef50_Q17HV9 Cluster: Titin; n=5; Endopterygota|Rep: Titin - Aedes aegypti (Yellowfever mosquito) Length = 7100 Score = 270 bits (663), Expect = 2e-70 Identities = 201/700 (28%), Positives = 306/700 (43%), Gaps = 40/700 (5%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENT 1353 R+ ++ G D + + Y AFP+P W N + + K + ++A + + T Sbjct: 4790 RDITVRAGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTRVHQQLTDEAAIFVVTNSKRT 4849 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 D+ Y+L L+N G+ N +LD+PS P + + +CW+ P + G S + Sbjct: 4850 DSKQYRLMLKNPSGYDIATCNAKVLDRPSKPENIGVESYGGEHLTLCWNAPLDDGGSPVT 4909 Query: 1414 YYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 YVVE +E +++ W V + T T I+NL+ N Y FR YA N+ +S+ +++ Sbjct: 4910 NYVVERKEKNSSNWTKVSSYCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDT--- 4966 Query: 1473 VIKETKIQSPTVE-KPLKNITTEPNEDIELTCIF----GGVPQPKVTWY-------RDGK 1520 +I + PT P + TTE + + +T I GG P +T Y +G Sbjct: 4967 IIAKHPFDVPTQPGTPTRVETTE--DSVTITWIKPASNGGSP---ITHYIVEKRPAAEGT 5021 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC------VVGIQQKPVIT 1574 K + T ++ ++ A N G+ S V P IT Sbjct: 5022 WTKVQQGTLKD-LMCKVSGLTENREYIFRVAAVNAAGQSPFSAASDPIMVTAAFTAPKIT 5080 Query: 1575 --ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I DI + D + + P P+ W NGN++ ++ + + ++ + Sbjct: 5081 SDIGMRDILVIAR--DPFKIIVPFSASPRPDAFWLVNGNEVSRNERIELQVTDTEAIFKN 5138 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 KR S YTI N G S + V DKP+ P GP+ + EI+ ES T+ WK PLD Sbjct: 5139 DNAKRLDSGSYTIHLVNCVGKDSASCRVLVVDKPTPPIGPLEVSEITPESCTLSWKVPLD 5198 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 DGG +T Y +E++EP W K + R Y + N +Y FRV A+N G S+ Sbjct: 5199 DGGSPITNYIVERYEP-LGYWTKASSFVRSTH-YDNMGMENNKQYSFRVRAENQYGISDP 5256 Query: 1753 L-ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EG 1810 L EPI+ + VP D V +TW +GGS I Y+ E + Sbjct: 5257 LILEEPIIARYPFTVPDPPNPPRVSDW-DASYVTVTWERPLMDGGSRIQGYRFEYRDVTD 5315 Query: 1811 KKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W + ++ L Y+FR+ A+N G S P S + I +TPPS P Sbjct: 5316 STWIVCNFLIKDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAP 5375 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929 V + V L WT P S+GGS IT Y +E + + G W K V E I N Sbjct: 5376 GAPAVIKVGKSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTELTITN 5435 Query: 1930 IKEKDEIIFRISAENTVGVSLP-TESQSVRLEKHATVPSP 1968 + E FR+ A N GVS P TE++SVR+ + P Sbjct: 5436 LIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKP 5475 Score = 251 bits (615), Expect = 1e-64 Identities = 335/1348 (24%), Positives = 547/1348 (40%), Gaps = 113/1348 (8%) Query: 705 EGT---YTVVAVNR--EGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQV 758 EGT + V A+NR EGEAS P I + +PP++ L ++ +R G + V Sbjct: 3462 EGTAYQFRVKAINRAGEGEASKPTDSHIARSKNQPPKIDRYSLSNVKIRAGLTFEFDVPV 3521 Query: 759 VGNPRPTITWC-KNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAE 815 G P P W K+N + K + + T L+ VK D GVYTL A+N GI Sbjct: 3522 QGEPVPAKEWTHKDNMIINTDRVKVVYENYR-TKLRVMDVKRSDSGVYTLTAKNKNGIDI 3580 Query: 816 TSA-VITVEEPTEENAEPPLFINRFQEITV-------KEKGTIKLVARVTRN-PVPSITW 866 V+ ++ P E P+ + V K+ G +++ V + W Sbjct: 3581 ADVNVVVLDVPAPP--EGPIRHENLSKTGVTLMWRPPKDDGGSEILHYVVEKLDTDQLRW 3638 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDS----GDYKCVASNSAGKSSH-GARV 921 E IS +G + + + V+ + +S A + K G V Sbjct: 3639 IPVGETISTKIRPDNLIEGHSYQFRVRAVNKQGESIPLSTSQPITAKDPYTKPDKPGKPV 3698 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981 +D +V L+ S ++G + I TS+ V K + + +G + Sbjct: 3699 VVDWSD-NYVT-LEWSIPKKDGGSPI----TSYVVEKKPRYGDWKFAGEFTELFKPHAKI 3752 Query: 982 XXXXXXXXXXXDV-GVIKCIVKD-QETSTMLVVKETI--PEFIRK-LQDFEVKEKDVAIL 1036 + V K V D E+S +V K P F + L+D V Sbjct: 3753 TDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRFVPPHFDKNALKDLIVPVGKKIAY 3812 Query: 1037 EVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094 V + S W+RDG +I P+ + E + L I + D G Y+ I+++ Sbjct: 3813 NVTVEASPNVTATWKRDGVVI-PESQRVIREAYNNEVSLEIPFSIREDCGMYTLIVKNSC 3871 Query: 1095 ---SCTAEVTVVELP--PEIITRLQN------------QKVNKGNKATFEIELTKGDALV 1137 S + VTV++ P PE R+ N K + G+ T + + Sbjct: 3872 GEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKMDMSRG 3931 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 W G +N I I K+ ++ +++ GE + A EEPS Sbjct: 3932 TWSAAGMSTSLANEISRLIHNKRYSFRVKA--VNEIGESEPLESSHPIVAKNDFEEPS-- 3987 Query: 1198 FTLRLPEFILVPANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVK--KRTL 1253 P+ + AN+ + L P D +T Y + +D+ ++ V +R L Sbjct: 3988 -QPPKPQVVDWDANSVS-LEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRVPGIQRNL 4045 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK-------LKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 + + + E+ + ++A ++ + PKIV R+ +K G Sbjct: 4046 KVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGLIFH 4105 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 L V++ P P W +N K ++ K T + + D+G YKL++ N+ Sbjct: 4106 LDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKLKISNSS 4165 Query: 1367 GHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI-DT 1424 G + +++T+LD+P PP G N EI S+ I W P++ G S I YVVE +++ Sbjct: 4166 GTDEGSLHLTVLDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSEITGYVVEKKDLTHG 4225 Query: 1425 TEWI-SVKNITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481 W+ +V ++ T T + L + Y FR A N SD + V+ + + Sbjct: 4226 GGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDG--LMSKHPVVAKDQFVV 4283 Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQ--PKVTWY----RD---GKKLKTAKATYENR 1532 P P K T+ N D + +++ Y RD G+ ++ K N Sbjct: 4284 P--GPPTKPDITDSNYDFITLSWKPPISDGGSRISGYNIERRDTATGRWIQANKYPIPN- 4340 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETS-----C-VVGIQQKPVITISNEDIKQ-KHK 1585 Y+ A N G+ + S C +QQ P + + + + K + Sbjct: 4341 IEFTDTGVMRGHQYDYRVSAVNAAGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVR 4400 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G+ ++T + G P P V W++NG K+ I T + +V R++ +R S Y I Sbjct: 4401 AGEPIIITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKI 4460 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 +ASN G + E + V D+P P V E ++++VT+ W PP DDGG E+T Y+IE Sbjct: 4461 KASNQYGEDTREFEVIVVDRPQPPRN-VFALETTQDTVTLNWDPPKDDGGSEITGYSIEY 4519 Query: 1706 HEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 E ++ W V V R T I+ L EN EY+FRV A+N G S+ ES+ I K+ Sbjct: 4520 KEFPSDNWKMVYGTVPRCAHT--IKHLTENHEYIFRVRAENIYGASDPTESKTISPKSP- 4576 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXX--XXX 1821 D P + S I+W P P+ Y VE ++ G +W Sbjct: 4577 DPPQTVDKPAVEDYTPS-SCTISWKPPRVQ-TRPVTGYIVEKRERGTGEWVQVNNYPTVN 4634 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 I L Y+FR+ + N++G S P D IT P+QP + + + + Sbjct: 4635 TTYTIPDLMEGFRYEFRVKSVNDVGVSKPSEPTDPITAQYQRKRPNQPDPPSIDKISRNN 4694 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG--SVHEHCIENIKEKDEIIFR 1939 VTL W + I Y+I+++ W + S + +EN++E E FR Sbjct: 4695 VTLSWRTLRRDAKEKIKGYLIQYRIKDEDKWIDSNSAADLCSDQSYRVENLEENKEYQFR 4754 Query: 1940 ISAENTVGVSLPTE-SQSVRLEKHATVP 1966 + A N +G S P+ S SV L++ P Sbjct: 4755 LIAVNDIGSSDPSRPSISVILQEQPNKP 4782 Score = 245 bits (600), Expect = 9e-63 Identities = 223/804 (27%), Positives = 339/804 (42%), Gaps = 58/804 (7%) Query: 1287 PPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 PPKI + RIK G++V V P P +W++N + +K+ + K + + Sbjct: 3199 PPKIDRTNLIDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKI 3258 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404 TI+ ++G Y + EN G + VT+LD PSPPG P + EI ++ + W P Sbjct: 3259 TIRSATRGESGTYTIEAENENGKDTATVFVTVLDVPSPPGGPLKVPEITANGAILEWRAP 3318 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 E+ G I Y++E + W+ +K Q I L SY+FR A N++ S Sbjct: 3319 EDDGGLPIDNYIIEKLDEAKGTWVYAGDSGSSKCQAEIDGLIEGHSYKFRVRAQNKMGKS 3378 Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVP-----QPKV 1513 + V+ + ++P + L IT + +EL GG P K+ Sbjct: 3379 EPLSMAN--AVVAKNPFRAPQRPENL-TITDYDKDYVELEWKAPENDGGAPITGYVVEKL 3435 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQ 1569 + Y G K A+ + ++ A N GE E T + + Sbjct: 3436 SKY-SGDWEKCAEVEGD-ACTAKVPDLIEGTAYQFRVKAINRAGEGEASKPTDSHIARSK 3493 Query: 1570 KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 I + K + G + ++G P P W N + N + + + Sbjct: 3494 NQPPKIDRYSLSNVKIRAGLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYRT 3553 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 +R+ ++KRS S YT+ A N G +V + V D P+ PEGP+ +S+ VT+ W+ Sbjct: 3554 KLRVMDVKRSDSGVYTLTAKNKNGIDIADVNVVVLDVPAPPEGPIRHENLSKTGVTLMWR 3613 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 PP DDGG E+ Y +EK + D RWI V + + + L E Y FRV A N Sbjct: 3614 PPKDDGGSEILHYVVEKLDTDQLRWIPVGETISTKIRP---DNLIEGHSYQFRVRAVNKQ 3670 Query: 1748 GFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 G S L S+PI K P DN V + W +K+GGSPI Y VE Sbjct: 3671 GESIPLSTSQPITAKDPYTKPDKPGKPVVVDWSDN-YVTLEWSIPKKDGGSPITSYVVEK 3729 Query: 1807 KQEGKKWKXXXXXXXX---XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 K WK A+I L + Y+FRI A N+ G S P S D I Sbjct: 3730 KPRYGDWKFAGEFTELFKPHAKITDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRF 3789 Query: 1864 TPPSQPRNFV------VSESTSRSVTLKWTEPESNGGSPITNYII-EFKTVKGKSWTKIV 1916 PP +N + V + + +VT++ P +I E + V +++ V Sbjct: 3790 VPPHFDKNALKDLIVPVGKKIAYNVTVE-ASPNVTATWKRDGVVIPESQRVIREAYNNEV 3848 Query: 1917 T--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + + S+ E C ++ + +N+ G + +V L+K PSPP PL Sbjct: 3849 SLEIPFSIREDC---------GMYTLIVKNSCGEYSASGHVTV-LDK----PSPPEGPLR 3894 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 I + + W P+ DGG+P+ Y I D+++ W G +L I L N Sbjct: 3895 ITNITTEGCHLEWKLPKDDGGSPITHYVIEKMDMSRGTWSAAGM--STSLANEISRLIHN 3952 Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058 Y R+ A NEIG SEPLES P Sbjct: 3953 KRYSFRVKAVNEIGESEPLESSHP 3976 Score = 239 bits (586), Expect = 5e-61 Identities = 206/781 (26%), Positives = 326/781 (41%), Gaps = 46/781 (5%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 G + V +A P W + +I + + + SL I D G+Y L Sbjct: 3807 GKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLI 3866 Query: 1362 LENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 ++N+CG +VT+LDKPSPP P I I + ++ W P++ G S I +YV+E Sbjct: 3867 VKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKM 3926 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 ++ W + T I L N Y FR AVNE+ S+ E++ + ++ + + Sbjct: 3927 DMSRGTWSAAGMSTSLANEISRLIHNKRYSFRVKAVNEIGESEPLESS--HPIVAKNDFE 3984 Query: 1481 SPTVEKPLKNITTEPNE-DIELTC--IFGGVPQPKVTWYRDGKKLK------TAKATYEN 1531 P+ + + + N +E GG P +T Y KK K TA Sbjct: 3985 EPSQPPKPQVVDWDANSVSLEWNAPKSDGGAP---ITEYIVQKKEKDSPYWSTAGRVPGI 4041 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQ--KPVITISNEDIKQKHK 1585 + ++ IA N GE E S V+ + P I D+ K Sbjct: 4042 QRNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVK-- 4099 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G + + G P PEV+W NG +E+DK +T +++ R S Y + Sbjct: 4100 AGLIFHLDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKL 4159 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 + SN++GT + L V D+P PEGP+ EI+ +SVTI WKPP D+GG E+T Y +EK Sbjct: 4160 KISNSSGTDEGSLHLTVLDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSEITGYVVEK 4219 Query: 1706 HE-PDNNRWI-KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKT 1762 + W+ VA V + +LN+ +Y FRV+A+N G S+ L S+ P+V K Sbjct: 4220 KDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLMSKHPVVAKD 4279 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXX 1821 VP + + + ++W P +GGS I Y +E + +W Sbjct: 4280 QFVVPGPPTKPDITDS-NYDFITLSWKPPISDGGSRISGYNIERRDTATGRWIQANKYPI 4338 Query: 1822 XXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 + Y +R+ A N G P K P Q + Sbjct: 4339 PNIEFTDTGVMRGHQYDYRVSAVNAAGQGQPSDPSSKC----WAKPMQQAPKLNLDSFGK 4394 Query: 1880 RSVTLKWTEP----ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKD 1934 R++ ++ EP G+PI VK ++ S H +E + KD Sbjct: 4395 RTIKVRAGEPIIITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKD 4454 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG 1994 ++I A N G E + + +++ P PP + + + +W P+ DG Sbjct: 4455 SDTYKIKASNQYGED-TREFEVIVVDR----PQPPRNVFALETTQDTVTL-NWDPPKDDG 4508 Query: 1995 GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 G+ + GY+I ++ W V V I+ L+ENH Y+ R+ A N G S+P E Sbjct: 4509 GSEITGYSIEYKEFPSDNWKMVYGT-VPRCAHTIKHLTENHEYIFRVRAENIYGASDPTE 4567 Query: 2055 S 2055 S Sbjct: 4568 S 4568 Score = 237 bits (580), Expect = 2e-60 Identities = 203/790 (25%), Positives = 320/790 (40%), Gaps = 35/790 (4%) Query: 1286 FPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342 F P +D + +K G + L P P W++N +++ K + + Sbjct: 2311 FAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYR 2370 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 A LTI V G Y+++ EN+ G+ + + +T+LDKP+ P P + + ++ W Sbjct: 2371 AKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITVLDKPTAPEGPLKVSNVHKEGCSLKW 2430 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 + P + G I +Y VE + +T W+ V T + NL+ Y FR AVN+ + Sbjct: 2431 NPPLDDGGVPIDHYNVEKFDKETGRWVPVGRTPDTHMDVTNLEPGQEYLFRVSAVNDEGV 2490 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT----CIFGGVPQPK-VTWY 1516 S+ T ++ ++ + P + + N IEL GG P K + Sbjct: 2491 SEPLSTEQF--IMAKNPFDEPGKPGTPEAYDWDRNF-IELRWTPPVCDGGSPITKYIVEK 2547 Query: 1517 RDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKP-- 1571 R+ +K +A N+ +K A N+ G V + I KP Sbjct: 2548 REHGTIKWIRAAEVIGNKCEAKVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPRK 2607 Query: 1572 -VITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 I ++K +G+ + I G P P+V W N + I S Sbjct: 2608 LPPKIDRRNLKNLSVAIGEPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYNSK 2667 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP 1689 R S KY I+A+N GT VE+T+ V KPS PEGP+ +++++++S +EW+ Sbjct: 2668 FANTNPDRRDSGKYVIKATNKFGTDQVEITVTVRSKPSAPEGPLEVKDMTKDSCRLEWQK 2727 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 P DDGG+ + Y +EK +PDN W+ V+ + ++ L Y FRV A N G Sbjct: 2728 PKDDGGVPIDHYVVEKFDPDNGIWMTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGE 2787 Query: 1750 SEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 S+ LES + K + VP +N +V + W P +GGSPI Y +E K Sbjct: 2788 SDPLESAGTYLAKDSFSVPDTPSAPTVVDWSENHAV-LKW-PEPDDGGSPITGYIIEKKD 2845 Query: 1809 E-GKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 + W+ A + L YQFR+ A N+ G S P + T P Sbjct: 2846 KYSPIWEKACETTSPSPTATVGGLVEGNEYQFRVIAVNKAGQSDPSDASRTFTAKPRFAP 2905 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P R + S S LK+ S +P + + TV +I+ + + Sbjct: 2906 PKIDRRTIRDISISAGSMLKFDVNVSGEPAPKCEWRVNKATVSSDRRLEILNTDYN-SKF 2964 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 + D + I+A N+ G +V P P PL++ V Sbjct: 2965 ILRPANRNDSGDYEITATNSSGRDYVCVQVTV-----TDKPGAPEGPLQVSDVTKETCKL 3019 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWM-EVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 W P DGG + Y I D W+ V+ N +I L Y R+ A Sbjct: 3020 KWKRPRDDGGCDIEYYQIERFDEDANAWVPHARSVETNA---DISGLQNGKKYKFRVSAV 3076 Query: 2045 NEIGLSEPLE 2054 N G S+PLE Sbjct: 3077 NAEGESKPLE 3086 Score = 235 bits (576), Expect = 7e-60 Identities = 204/778 (26%), Positives = 332/778 (42%), Gaps = 32/778 (4%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 IK G V +D + P P +W K ++ + ++D + ++ N +G Sbjct: 1734 IKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNL-SGK 1792 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y + N+ G E+ +TIL KP P P E+ + W P + G I Y Sbjct: 1793 YTIVATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKPPLDDGGMPIDGYE 1852 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E + T +WI + + +I L+ Y+FR A N+ S+ E E + K+ Sbjct: 1853 IEKLDPLTGQWIPCGQSSTPEANISGLQEGKQYKFRVKAFNKEGDSEPLEM-ETIVIAKD 1911 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTC--IFGGVPQPK-VTWYRD--GKKLKTAKATYEN 1531 + +P + D+E T GG P + + RD +K + A + Sbjct: 1912 PFSEPSKPGRPTPTDWGKDFVDLEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGD 1971 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKP---VITISNEDIKQKH-KV 1586 R ++ IA N G E S + + KP I +++ +K + Sbjct: 1972 RTRGTVEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRF 2031 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G V A + G P P++ W G + + D+ + ++ + + I+ LKRS S Y Sbjct: 2032 GQLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYK 2091 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + A N GT +VE+ L V KPSK GP+ + +++ E + W PP DDGG + Y +E Sbjct: 2092 VTAKNKNGTDTVEMELVVLAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQAYVVE 2151 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTA 1763 + + D+ RWI+V + R E + L E +YMFRV A N G SE LE+E K Sbjct: 2152 RMDVDSGRWIQVCET-RFPEAD-VSGLQEGKDYMFRVKAVNSEGESEPLETETSTRAKNP 2209 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXX- 1821 D PS + V + W E +GG+PI Y +E K KW Sbjct: 2210 YDAPSAPGKPKATDW-SRKHVMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAMETDGP 2268 Query: 1822 -XXARIQKLSINTTYQFRIYARNEIGTSLPYTS-DDKITIGKTLTPPSQPRNFVVSESTS 1879 A++Q L TTYQFR+ A N+ G S PY+ D + + PP R+ + + + Sbjct: 2269 VNKAKVQDLFEGTTYQFRVKAVNKGGPS-PYSPLSDPVLVKDRFAPPRIDRSTLKNMTLK 2327 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 +L+ S +P +++ V+ + V + I + + Sbjct: 2328 GGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTYE 2387 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 I AEN+ G + +V L+K P+ P PL++ V W P DGG P+ Sbjct: 2388 IKAENSSGYDEHQFTITV-LDK----PTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVPID 2442 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 YN+ D W+ VG+ ++ +L Y+ R+ A N+ G+SEPL +++ Sbjct: 2443 HYNVEKFDKETGRWVPVGRTP--DTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQ 2498 Score = 229 bits (561), Expect = 5e-58 Identities = 237/932 (25%), Positives = 393/932 (42%), Gaps = 79/932 (8%) Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYK 1231 AG+ +SKC A + P +N I V A +T+ + + V W++ Sbjct: 4364 AGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVRAGEPIIITIPLVGAPIPTVEWFR 4423 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP-- 1287 I +T + T+ ++ + + + D Y + + T + +V VV+ P Sbjct: 4424 NGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKIKASNQYGEDTREFEVIVVDRPQP 4483 Query: 1288 PKIV---DYEREY--------RIKRGSDVT-LLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 P+ V + ++ + GS++T ++Y+ FP +D W + + +C HT Sbjct: 4484 PRNVFALETTQDTVTLNWDPPKDDGGSEITGYSIEYKEFP--SDNWKMVYGTVPRCAHT- 4540 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPP---GKPNILE 1391 IK + I+++R EN G +D + TI K P PP KP + + Sbjct: 4541 -----------IKHLTENHEYIFRVRAENIYGASDPTESKTISPKSPDPPQTVDKPAVED 4589 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSY 1449 SS I W +P + Y+VE +E T EW+ V N T+ I +L Y Sbjct: 4590 YTPSSCTISW-KPPRVQTRPVTGYIVEKRERGTGEWVQVNNYPTVNTTYTIPDLMEGFRY 4648 Query: 1450 RFRAYAVNEVDISDASETTE----YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-- 1503 FR +VN+V +S SE T+ Y+ + + P+++K +N T + Sbjct: 4649 EFRVKSVNDVGVSKPSEPTDPITAQYQRKRPNQPDPPSIDKISRNNVTLSWRTLRRDAKE 4708 Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE 1560 I G + Q ++ +D K + + + Y + IA ND G + Sbjct: 4709 KIKGYLIQYRI---KDEDKWIDSNSAADLCSDQSYRVENLEENKEYQFRLIAVNDIGSSD 4765 Query: 1561 TS----CVVGIQQ--KPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 S V+ +Q KP++ + N DI + G+++ + P P W+ N +L Sbjct: 4766 PSRPSISVILQEQPNKPMMDLRNVRDITVR--AGEDFNIHIPYTAFPKPVATWFANDEQL 4823 Query: 1614 EN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++ D + ++ ++ + KR+ S +Y + N +G KV D+PSKPE Sbjct: 4824 DDKDTRVHQQLTDEAAIFVVTNSKRTDSKQYRLMLKNPSGYDIATCNAKVLDRPSKPEN- 4882 Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKL 1731 + + E +T+ W PLDDGG +T Y +E+ E +++ W KV+ TY I+ L Sbjct: 4883 IGVESYGGEHLTLCWNAPLDDGGSPVTNYVVERKEKNSSNWTKVSSY--CTTTYLKIRNL 4940 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 N +Y FRV A+N G SE +S+ I+ K DVP+ + +SV ITW Sbjct: 4941 RINQQYEFRVYAENKYGMSEPAQSDTIIAKHPFDVPTQPGTPTRVETTE-DSVTITWIKP 4999 Query: 1792 EKNGGSPIIDYKVEIK--QEGKKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 NGGSPI Y VE + EG K ++ L+ N Y FR+ A N G S Sbjct: 5000 ASNGGSPITHYIVEKRPAAEGTWTKVQQGTLKDLMCKVSGLTENREYIFRVAAVNAAGQS 5059 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSE-STSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 + D I + T P + + + K P S P +++ V Sbjct: 5060 PFSAASDPIMVTAAFTAPKITSDIGMRDILVIARDPFKIIVPFSASPRPDAFWLVNGNEV 5119 Query: 1908 KGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 ++ VT ++ ++ +N K D + I N VG +S S R+ P Sbjct: 5120 SRNERIELQVTDTEAIFKN--DNAKRLDSGSYTIHLVNCVG----KDSASCRV-LVVDKP 5172 Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 +PP PLE+ + SW P DGG+P+ Y I R W + V + + Sbjct: 5173 TPPIGPLEVSEITPESCTLSWKVPLDDGGSPITNY-IVERYEPLGYWTKASSF-VRSTHY 5230 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + N Y R+ A N+ G+S+PL +EP Sbjct: 5231 DNMGMENNKQYSFRVRAENQYGISDPLILEEP 5262 Score = 229 bits (560), Expect = 6e-58 Identities = 296/1272 (23%), Positives = 483/1272 (37%), Gaps = 75/1272 (5%) Query: 841 EITVKEKGTIKLVARVT-RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 +IT KE K++ P W + I +G+ +I N E Sbjct: 170 DITCKEGREKKVIFECAFTKPNAKAKWMLRKDEIFTGPKYKFKTEGDVYSCLIINPKVE- 228 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVILECQTSHTVST 958 DSG Y AG S + + V F K L+K+ + LEC ++++ Sbjct: 229 DSGKYTI---EIAGISCFAYLTVEEADPVYKFTKTLKKNEKGFITHDTHLECAVDNSLAP 285 Query: 959 -KWYHNKKEISGMDHREIIQE--GRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVK 1013 W+ + ++ + +I + D C ++ Q +T T L + Sbjct: 286 ISWWKGETKLENDGEKYVIGKDLNGTVTLIIKNSVLEDADTYTCKIEKQTDKTETKLKIL 345 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 E +F + L+ ++ KD L E++ V W + E I + +K K G K Sbjct: 346 EYNYKFTKVLKSQQLFVKDTVTLACELDHVLGTVEWFKGDEKIV-ESDKVQIIKDGRKHK 404 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133 L +++ + D G Y C+ + AE+ V+ P + + +L++ ++ + +I++ Sbjct: 405 LVLKDVAKADSGMYRCVSNADKTEAEI-FVKRPNKFMKKLKDTTGDETKECVLDIQVQDE 463 Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVG--NSKCTAILT 1190 +A V++F +EI ++ I + G KL +L DAGE +C G SKCT + Sbjct: 464 EADVQFFLGETEIVKNDRIDIVSPGDGTWKLVYKKLELGDAGEITCVCGPLTSKCTLKVN 523 Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTV-----EIPDETLDVTWYKKKSVIEDTEKFTLI 1245 +E F +P + PA + L V E + +K + E ++ Sbjct: 524 KKETKPKF--EVPPKVETPAKVEKVLEVPFTTGESRQSKVTAKVFKVGKPVTPAE-VDIV 580 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKRGS 1303 + K L +K D E+ VL +A + VV + P D E + Sbjct: 581 VENDKLVLKFKKTEFQDSGEFKIVLENATGAEEHTTNVVFQDKPQAPQDIECTNIFQTRC 640 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 V P ++++ + + K D + T YK R++ Sbjct: 641 VVKWKAPVNDGGAPLTKYVLERQDVFKRSGWDKLEDVPGDQTKFSVTDLTPGRHYKFRVK 700 Query: 1364 --NNCGHAD---VEMNVTILD---KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 N G +D +E ++ D +P PP I D +++ W P++ G + I Y Sbjct: 701 AVNKMGESDYCSMEEDIIAKDPWNEPDPPRDLVISNWDKEFVDLAWKVPKSDGGAPIQSY 760 Query: 1416 VVEYQEIDTTEWISVKNITKTQ--TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +VEY+ W + + TQ T+++NL ++ FR A N+ S S +TE K+ Sbjct: 761 IVEYKPYTAANWKQYETVGPTQLKTTVKNLTVGETFEFRVKATNQGGESKPSNSTEPLKI 820 Query: 1474 IKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGKKLKTA 1525 + P +E +K IT + + I +GG P+P+V W + D +K KT Sbjct: 821 --RDRYVKPFIEGDGIKPITLKKGQTIRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTI 878 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQ 1582 YK N GE T+ V+ + +PV I E + Sbjct: 879 DVE-SCATTLNVRHSVRADSGTYKLKLKNSSGEFVTAAKVLVLDVPSQPVGPIKIEKARS 937 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 H V W G P + K + + E+ + + L++ + Sbjct: 938 NHVV-ISWQPPEDTGGCPLTGYLLEKMDVENGTWLQAGECGPEQLT-FDFQHLQKGRKFE 995 Query: 1643 YTIEASNTAGTSS-VEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + ++A N G S+ +E L V YD P P P + + + V ++W P DGG Sbjct: 996 FRVKAYNKEGESTPLETLLAVKTVNPYDPPEAPGKPAV-DDYGVDFVELKWAAPEKDGGR 1054 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALE- 1754 +T Y IE W + A + +T C + L E Y FRV A N G S+ E Sbjct: 1055 PVTHYIIECKNKFMTDWGECAKTETP-DTVCKVHGLKEKVVYQFRVRAVNKGGTSKPSEP 1113 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK---QEGK 1811 SE +K P I + W K P I + + Sbjct: 1114 SENHTVKHKNLKPRIDRTNLKNLTI-KVGKSMLWSVDVKGEPEPDISWSWRDNIPLTVSE 1172 Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 K I+ T +++I A N G + + +G P Sbjct: 1173 NIKIETGNYHTNFSIKDAKRADTGKYKILATNASGKD--EAEVELVVLG---APGKCQGK 1227 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV--GGSVHEHCIEN 1929 VS T + + LKW +P +GG PI Y IE + W + TV G + E I Sbjct: 1228 LEVSNVTKKGLKLKWKKPLDDGGCPIKEYKIEKLKNRNGKWVRCGTVKGGPEILEADITG 1287 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 + E FR+ N G S P ES+ V + P P P EI + V W Sbjct: 1288 LDEGATYKFRVFGVNDEGESEPLESEEVVAKNPFDEPWKPGQP-EIVDFDNKSVKLKWAP 1346 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 P+ DGGAP+ Y I ++ K W +V +V + + DL EN RI A N+ G Sbjct: 1347 PKSDGGAPITQYVIQKKERFKD-WEDVKEVPGHETTATVEDLKENTELQFRIVAVNKAGR 1405 Query: 2050 SEPLESDEPFKV 2061 S + KV Sbjct: 1406 SPESDPTATHKV 1417 Score = 228 bits (557), Expect = 1e-57 Identities = 197/792 (24%), Positives = 319/792 (40%), Gaps = 35/792 (4%) Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 PPKI R+ I GS + V+ P P EW VN + + + ++ Sbjct: 2905 PPKIDRRTIRDISISAGSMLKFDVNVSGEPAPKCEWRVNKATVSSDRRLEILNTDYNSKF 2964 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEP 1404 ++ D+G Y++ N+ G V + VT+ DKP P P + ++ + + W P Sbjct: 2965 ILRPANRNDSGDYEITATNSSGRDYVCVQVTVTDKPGAPEGPLQVSDVTKETCKLKWKRP 3024 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 + G I YY +E + D W+ +T I L+ Y+ + V+ V+ Sbjct: 3025 RDDGGCDIEYYQIERFDEDANAWVPHARSVETNADISGLQNGKKYK---FRVSAVNAEGE 3081 Query: 1465 SETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCI----FGGVP-QPKVTWYRD 1518 S+ E I + P+ + K P + ++L + GG P V +D Sbjct: 3082 SKPLEQVGDFIAKNPFDEPSAPQNCKATDWGP-DFVKLAWLPPISDGGSPITGYVVEVKD 3140 Query: 1519 --GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGI-----QQK 1570 G+ K + + ++ A ND G ++ I Q Sbjct: 3141 KYGEWEKKMQVPAD-ATAAEVPDLMEGQKYEFRVRAVNDAGPGAPSNATPPIICKPKNQP 3199 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P I +N I + K G+ + + G P P W N +L+ ++ + I + + I Sbjct: 3200 PKIDRTNL-IDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKI 3258 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690 I+ R S YTIEA N G + V + V D PS P GP+ + EI+ +EW+ P Sbjct: 3259 TIRSATRGESGTYTIEAENENGKDTATVFVTVLDVPSPPGGPLKVPEITANGAILEWRAP 3318 Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 DDGGL + Y IEK + W+ D I L E Y FRV AQN +G S Sbjct: 3319 EDDGGLPIDNYIIEKLDEAKGTWVYAGDSGSSKCQAEIDGLIEGHSYKFRVRAQNKMGKS 3378 Query: 1751 EALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQ 1808 E L + +V K P D + V + W E +GG+PI Y VE + + Sbjct: 3379 EPLSMANAVVAKNPFRAPQ-RPENLTITDYDKDYVELEWKAPENDGGAPITGYVVEKLSK 3437 Query: 1809 EGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 W+ A++ L T YQFR+ A N G D PP Sbjct: 3438 YSGDWEKCAEVEGDACTAKVPDLIEGTAYQFRVKAINRAGEGEASKPTDSHIARSKNQPP 3497 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 R + + +T ++ P P + + + K+V Sbjct: 3498 KIDRYSLSNVKIRAGLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYRTKLR- 3556 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 + ++K D ++ ++A+N G+ + + V L+ VP+PP P+ + V Sbjct: 3557 VMDVKRSDSGVYTLTAKNKNGIDI-ADVNVVVLD----VPAPPEGPIRHENLSKTGVTLM 3611 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ DGG+ +L Y + D + W+ VG+ ++T K +L E H+Y R+ A N+ Sbjct: 3612 WRPPKDDGGSEILHYVVEKLDTDQLRWIPVGET-IST-KIRPDNLIEGHSYQFRVRAVNK 3669 Query: 2047 IGLSEPLESDEP 2058 G S PL + +P Sbjct: 3670 QGESIPLSTSQP 3681 Score = 223 bits (544), Expect = 6e-56 Identities = 208/808 (25%), Positives = 331/808 (40%), Gaps = 51/808 (6%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 IK G + VD + P+P+ W I + ++ K + + +IK + D G Sbjct: 1138 IKVGKSMLWSVDVKGEPEPDISWSWRDNIPLTVSENIKIETGNYHTNFSIKDAKRADTGK 1197 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 YK+ N G + E+ + +L P GK + + + + W +P + G I Y Sbjct: 1198 YKILATNASGKDEAEVELVVLGAPGKCQGKLEVSNVTKKGLKLKWKKPLDDGGCPIKEYK 1257 Query: 1417 VEYQEIDTTEWI---SVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 +E + +W+ +VK + + I L ++Y+FR + VN+ S+ E+ E Sbjct: 1258 IEKLKNRNGKWVRCGTVKGGPEILEADITGLDEGATYKFRVFGVNDEGESEPLESEE--- 1314 Query: 1473 VIKETKIQSPTVEKPLK-NITTEPNEDIELTCI----FGGVP--QPKVTWYRDGKKLKTA 1525 V+ + P KP + I N+ ++L GG P Q + K + Sbjct: 1315 VVAKNPFDEPW--KPGQPEIVDFDNKSVKLKWAPPKSDGGAPITQYVIQKKERFKDWEDV 1372 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVIT-ISNEDIK 1581 K + ++ +A N G E + + ++ + + I ++K Sbjct: 1373 KEVPGHETTATVEDLKENTELQFRIVAVNKAGRSPESDPTATHKVKHRALKPRIDRTNLK 1432 Query: 1582 QKHKVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS-H 1639 G + + V ++G P PE+ W + D Y I K+ + IK+ RS H Sbjct: 1433 PIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNTKFTIKDSMRSKH 1492 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 S Y I A N G +V + V PSKP+GP+ ++++++ ++WK P DDGG +T Sbjct: 1493 SGVYEIIAKNEHGMDKEKVEITVLASPSKPKGPLEVKDVTKNGCKLKWKKPEDDGGKPIT 1552 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEP-I 1758 Y +EK++ RW+ + D E + + L E Y FRV A N G SE LE+E Sbjct: 1553 GYQLEKYDQKVGRWVPIGKTPGDTEEFDVTGLQEGQHYKFRVKAINDEGESEPLETEEYT 1612 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXX 1817 V K D P DN SV + W +GG+PI Y +E K+ G+ KW+ Sbjct: 1613 VAKNPFDKPKAPTDLVINDW-DNSSVTLQWKRPSSDGGAPISGYFIEKKERGETKWEPAL 1671 Query: 1818 XXXX--XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 A+I L TYQFR+ A N+ GT T+ P R + Sbjct: 1672 TTYSPECQAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTP 1731 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + +++++ +P TVK K V ++ I+N+ + Sbjct: 1732 ITIKAGLSVQYDIDIEGEPAP---------TVKWFHGDKEVVTDA---DYKIDNVDYNTK 1779 Query: 1936 IIFRISAENTVG--VSLPTESQSV-RLEKHATV---PSPPTAPLEIRMVGSNIVMTSWGT 1989 N G + T SQ R E T+ P P PLE V + W Sbjct: 1780 FFIMRGRRNLSGKYTIVATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKP 1839 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 P DGG P+ GY I D W+ G+ +T + NI L E Y R+ A N+ G Sbjct: 1840 PLDDGGMPIDGYEIEKLDPLTGQWIPCGQ--SSTPEANISGLQEGKQYKFRVKAFNKEGD 1897 Query: 2050 SEPLESDEPFKVIPGEGSHADEEPGEQT 2077 SEPLE + VI + +PG T Sbjct: 1898 SEPLEMET--IVIAKDPFSEPSKPGRPT 1923 Score = 202 bits (492), Expect = 1e-49 Identities = 131/478 (27%), Positives = 216/478 (45%), Gaps = 14/478 (2%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQT 1438 PS PG P ++++ S +++ W P + G S I Y VE ++I W+ NI T+ Sbjct: 5372 PSAPGAPAVIKVGKSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTEL 5431 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 +I NL Y FR YAVN +S S T ++ ++ + P K LK + Sbjct: 5432 TITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGKS 5491 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFN 1554 ++LTC G P+P W R+GK++ + A + Y C A N Sbjct: 5492 VQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALN 5551 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 G + T+ V I P + D+ GD + G P EV K+ KL Sbjct: 5552 FVGAIHTTAAVKIGVPPKLVNIPSDVYLIK--GDNAKIKLGFSGDHPMEVNISKDREKLV 5609 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 + T + +VI I++++ S Y + N +G+ S V + V P P GP++ Sbjct: 5610 ETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSGSVSCNVNVHVTGLPGPPTGPLL 5669 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 + +++ T+ WKPP DGG ++T Y +E+ + + W+ V++ ++ + I+ L E Sbjct: 5670 ISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIVSNYIKETQ-LIIKGLIEF 5728 Query: 1735 CEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 EY+FRV A N G LE ++PI + D+PS + + V + W Sbjct: 5729 SEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPS-PPGIPIIHEVGGDFVNLEWDKPFS 5787 Query: 1794 NGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTS 1848 +GG+ I+ Y +E +++G W+ I L Y+FR+ A+NE+G S Sbjct: 5788 DGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAAQNEVGCS 5845 Score = 201 bits (491), Expect = 1e-49 Identities = 172/704 (24%), Positives = 293/704 (41%), Gaps = 36/704 (5%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKT 1436 DKP P I + D+SS+ + W P + G + I Y +E +E T+W + Sbjct: 1619 DKPKAPTDLVINDWDNSSVTLQWKRPSSDGGAPISGYFIEKKERGETKWEPALTTYSPEC 1678 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495 Q I +L +Y+FR A+N+ +AS+ T ++ V + + P +++ L IT + Sbjct: 1679 QAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTV--KHRYLRPRIDRTNLTPITIKA 1736 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYEN---RXXXXXXXXXXXXXXXYKCI 1551 ++ G P P V W+ K++ T A +N Y + Sbjct: 1737 GLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNLSGKYTIV 1796 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKN 1609 A N GE + I KP + + HK G + W G+P + Y+ Sbjct: 1797 ATNSQGEDRAEVEITILSKPGTPEGPLEASEVHKHGCKLKWKPPLDDGGMP---IDGYEI 1853 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVTLKVY 1663 ++ + T I L+ K+ ++A N G S ++ + + Sbjct: 1854 EKLDPLTGQWIPCGQSSTPEANISGLQEGKQYKFRVKAFNKEGDSEPLEMETIVIAKDPF 1913 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 +PSKP P + ++ V +EW P DGG +T+Y I+K + + +W A V D Sbjct: 1914 SEPSKPGRPT-PTDWGKDFVDLEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGDR 1972 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 ++ + E EY FRVIA N G SE + V+ ++ + Sbjct: 1973 TRGTVEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFG 2032 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQKLSINTTYQFRI 1839 + +P I ++++ K +E ++ + I+ L + + +++ Sbjct: 2033 QLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKV 2092 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPIT 1898 A+N+ GT T + ++ + L PS+ VS+ T+ L W PE +GG P+ Sbjct: 2093 TAKNKNGTD---TVEMELVV---LAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQ 2146 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ-SV 1957 Y++E V W ++ E + ++E + +FR+ A N+ G S P E++ S Sbjct: 2147 AYVVERMDVDSGRWIQVCET--RFPEADVSGLQEGKDYMFRVKAVNSEGESEPLETETST 2204 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 R + PS P P + VM W PE DGGAP+ Y I +D+ T WM+ Sbjct: 2205 RAKNPYDAPSAPGKPKATDWSRKH-VMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAM 2263 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + D K ++DL E TY R+ A N+ G S +P V Sbjct: 2264 ETDGPVNKAKVQDLFEGTTYQFRVKAVNKGGPSPYSPLSDPVLV 2307 Score = 201 bits (490), Expect = 2e-49 Identities = 173/706 (24%), Positives = 303/706 (42%), Gaps = 42/706 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKNITKT 1436 +P+ P P+I +I +++ + W I Y+++Y+ D +WI S ++ Sbjct: 4678 RPNQPDPPSIDKISRNNVTLSWRTLRRDAKEKIKGYLIQYRIKDEDKWIDSNSAADLCSD 4737 Query: 1437 QT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTE 1494 Q+ ++NL+ N Y+FR AVN++ SD S + VI + + P ++ + +++IT Sbjct: 4738 QSYRVENLEENKEYQFRLIAVNDIGSSDPSRPS--ISVILQEQPNKPMMDLRNVRDITVR 4795 Query: 1495 PNEDIELTCIFGGVPQPKVTWYR-----DGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 ED + + P+P TW+ D K + + + Y+ Sbjct: 4796 AGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTRVHQQLTDEAAIFVVTNSKRTDSKQYR 4855 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIPPPEVIWY 1607 + N G +C + +P E+I + G+ + A ++ P V Y Sbjct: 4856 LMLKNPSGYDIATCNAKVLDRPS---KPENIGVESYGGEHLTLCWNAPLDDGGSP-VTNY 4911 Query: 1608 KNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE-----VTLK 1661 K +N + +++ T+ ++I+ L+ + ++ + A N G S + Sbjct: 4912 VVERKEKNSSNWTKVSSYCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDTIIAKH 4971 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 +D P++P P + E + +SVTI W P +GG +T Y +EK W KV Sbjct: 4972 PFDVPTQPGTPTRV-ETTEDSVTITWIKPASNGGSPITHYIVEKRPAAEGTWTKVQQGTL 5030 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXI- 1779 + L EN EY+FRV A N G S + S+PI++ A P + Sbjct: 5031 KDLMCKVSGLTENREYIFRVAAVNAAGQSPFSAASDPIMVTAAFTAPKITSDIGMRDILV 5090 Query: 1780 ---DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQ 1836 D + + + S + +++ + E + + K + +Y Sbjct: 5091 IARDPFKIIVPFSASPRPDAFWLVNGNEVSRNERIELQVTDTEAIFKNDNAKRLDSGSYT 5150 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 I+ N +G ++ ++ + TPP P VSE T S TL W P +GGSP Sbjct: 5151 --IHLVNCVGKD---SASCRVLVVDKPTPPIGPLE--VSEITPESCTLSWKVPLDDGGSP 5203 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 ITNYI+E G WTK + S H + ++ + FR+ AEN G+S P + Sbjct: 5204 ITNYIVERYEPLGY-WTKASSFVRSTHYDNM-GMENNKQYSFRVRAENQYGISDPLILEE 5261 Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + ++ TVP PP P + ++ V +W P DGG+ + GY RDVT + W+ Sbjct: 5262 PIIARYPFTVPDPPNPP-RVSDWDASYVTVTWERPLMDGGSRIQGYRFEYRDVTDSTWI- 5319 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 V + + + +L Y R+ A+N G+S+P S + FK+ Sbjct: 5320 VCNFLIKDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKI 5365 Score = 199 bits (486), Expect = 6e-49 Identities = 173/676 (25%), Positives = 279/676 (41%), Gaps = 29/676 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 PE + RL+ V G E K + RW ++G EI L L I Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHI 5534 Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 + D G+Y+CE VG TA + + P + +++ N L Sbjct: 5535 SNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFS-G 5593 Query: 1222 DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT- 1277 D ++V K + + +TE K+T+ D + IR + D+ Y D+ S + Sbjct: 5594 DHPMEVNISKDREKLVETEHIKYTVFDDYA--VIYIRDVEDSDKGVYLVNFKNDSGSVSC 5651 Query: 1278 KLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 + V V P P + K V+ + ++V + IK Sbjct: 5652 NVNVHVTGLPGPPTGPLLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIV 5711 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGH-ADVEMNVTI-----LDKPSPPGKPNIL 1390 S K L IK + ++++ N G A +E I D PSPPG P I Sbjct: 5712 SNYIKETQLIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSPPGIPIIH 5771 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSS 1448 E+ +N+ WD+P + G + I+ Y +E +E T W V ++ + +I NL Sbjct: 5772 EVGGDFVNLEWDKPFSDGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRF 5831 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 Y FR A NEV S+ S+ ++ K + P V KPL +T N ++E C GV Sbjct: 5832 YEFRVAAQNEVGCSEFSKASQLVKAEDPDICKPPEVVKPLNTLTCVQNRNVEFVCKITGV 5891 Query: 1509 PQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 P+PK+TW++ +++ + Y + Y C A N G T Sbjct: 5892 PRPKITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKSTKAS 5951 Query: 1565 VGIQQKPVITISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + I+ P + + G+ + G P P W G ++E+ Y+I T Sbjct: 5952 LIIKSPPKLNVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIET 6011 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 +E+ +V+ I++ + S YTI N G + ++ +++ D P KP + + +I + V Sbjct: 6012 RERHTVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKPRN-LTVDQIGLDHV 6070 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 T+ W PP DGG +T Y +EK E + WI+ A R I L+ +Y FRV A Sbjct: 6071 TLSWLPPSWDGGASITNYIVEKREVPLSTWIR-AGTTR-FNQLIIPHLSPGHQYEFRVFA 6128 Query: 1744 QNPVGFSEALESEPIV 1759 +N G SE + +V Sbjct: 6129 ENVYGRSEPSDQTELV 6144 Score = 194 bits (474), Expect = 2e-47 Identities = 136/477 (28%), Positives = 214/477 (44%), Gaps = 16/477 (3%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKY 1643 K G + I G P P W N ++E D E + ++ + + I + R+H+ Y Sbjct: 2327 KGGQSLRLDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTY 2386 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 I+A N++G + T+ V DKP+ PEGP+ + + +E +++W PPLDDGG+ + Y + Sbjct: 2387 EIKAENSSGYDEHQFTITVLDKPTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVPIDHYNV 2446 Query: 1704 EKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEP-IVIK 1761 EK + + RW+ V R +T+ + L EY+FRV A N G SE L +E I+ K Sbjct: 2447 EKFDKETGRWVPVG---RTPDTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQFIMAK 2503 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXX 1818 D P D + + W P +GGSPI Y VE ++ G KW Sbjct: 2504 NPFDEPGKPGTPEAYDW-DRNFIELRWTPPVCDGGSPITKYIVEKREHGTIKWIRAAEVI 2562 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 A++ +L+ Y+F++ A NE G + IT PP R + + S Sbjct: 2563 GNKCEAKVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPRKLPPKIDRRNLKNLSV 2622 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 + + S +P ++ I + V + I V + + N +D + Sbjct: 2623 AIGEPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYN-SKFANTNPDRRDSGKY 2681 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 I A N G + +VR + PS P PLE++ + + W P+ DGG P+ Sbjct: 2682 VIKATNKFGTDQVEITVTVR-----SKPSAPEGPLEVKDMTKDSCRLEWQKPKDDGGVPI 2736 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 Y + D +WM GKV+ +F + L H Y R+ A N G S+PLES Sbjct: 2737 DHYVVEKFDPDNGIWMTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGESDPLES 2793 Score = 192 bits (469), Expect = 7e-47 Identities = 196/872 (22%), Positives = 361/872 (41%), Gaps = 54/872 (6%) Query: 1227 VTWYKKKSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 +TW K I ++ E+ L ++ K LIIR D Y + T +++E+V Sbjct: 2049 ITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKNKNGTDTVEMELV 2108 Query: 1285 EF--PPKIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 P K + + + G + L +P ++V + + + +++ Sbjct: 2109 VLAKPSKCMGPLKVSDVTAEGCKLAWLPPEDDGGEPVQAYVVERMDVDSGRWIQVC-ETR 2167 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTI-----LDKPSPPGKPNILEIDSS 1395 + ++ +++++ N+ G ++ +E + D PS PGKP + Sbjct: 2168 FPEADVSGLQEGKDYMFRVKAVNSEGESEPLETETSTRAKNPYDAPSAPGKPKATDWSRK 2227 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK--TQTSIQNLKTNSSYRFRA 1453 + + W EPE+ G + I Y++E ++I++T+W+ + +Q+L ++Y+FR Sbjct: 2228 HVMLEWAEPESDGGAPITKYIIEKKDINSTKWMKAMETDGPVNKAKVQDLFEGTTYQFRV 2287 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPK 1512 AVN+ S S ++ V+ + + P +++ LKN+T + + + L C G P P Sbjct: 2288 KAVNKGGPSPYSPLSD--PVLVKDRFAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPT 2345 Query: 1513 VTWYRDGKKLKT----AKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 W + +++ + +E+ R Y+ A N G E + + Sbjct: 2346 KYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITV 2405 Query: 1568 QQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-K 1624 KP + HK G +W G+P I + N K + + + + Sbjct: 2406 LDKPTAPEGPLKVSNVHKEGCSLKWNPPLDDGGVP----IDHYNVEKFDKETGRWVPVGR 2461 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTS---SVEVTLKV---YDKPSKPEGPVIMREI 1678 + + + L+ + + A N G S S E + +D+P KP P + Sbjct: 2462 TPDTHMDVTNLEPGQEYLFRVSAVNDEGVSEPLSTEQFIMAKNPFDEPGKPGTPEAY-DW 2520 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 R + + W PP+ DGG +TKY +EK E +WI+ A+V + + +LNE Y Sbjct: 2521 DRNFIELRWTPPVCDGGSPITKYIVEKREHGTIKWIRAAEVIGNKCEAKVTELNEGEVYE 2580 Query: 1739 FRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG- 1796 F+V A N G + S+PI K P + + F + +G Sbjct: 2581 FKVRAVNEAGPGVWSDHSKPITAKPRKLPPKIDRRNLKNLSVAIGEPF--GFDVKISGEP 2638 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINT--TYQFRIYARNEIGTSLPYTSD 1854 +P +D+ + + ++ + + + ++ I A N+ GT Sbjct: 2639 APDVDWTINDRMVTVTTTRTIDNVPYNSKFANTNPDRRDSGKYVIKATNKFGT------- 2691 Query: 1855 DKITIGKTL-TPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 D++ I T+ + PS P V + T S L+W +P+ +GG PI +Y++E W Sbjct: 2692 DQVEITVTVRSKPSAPEGPLEVKDMTKDSCRLEWQKPKDDGGVPIDHYVVEKFDPDNGIW 2751 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTA 1971 V E +E + FR+ A N G S P ES L K + +VP P+A Sbjct: 2752 MTAGKVEWPFTEFPVEGLIPGHRYKFRVKAVNAEGESDPLESAGTYLAKDSFSVPDTPSA 2811 Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031 P + ++ V+ W P+ DGG+P+ GY I +D +W + + + + L Sbjct: 2812 PTVVDWSENHAVL-KWPEPD-DGGSPITGYIIEKKDKYSPIWEKACETTSPSPTATVGGL 2869 Query: 2032 SENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 E + Y R+ A N+ G S+P ++ F P Sbjct: 2870 VEGNEYQFRVIAVNKAGQSDPSDASRTFTAKP 2901 Score = 192 bits (469), Expect = 7e-47 Identities = 171/700 (24%), Positives = 281/700 (40%), Gaps = 47/700 (6%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT---KT 1436 KP PGKP +++ + + + W P+ G S I YVVE ++ +W T K Sbjct: 3690 KPDKPGKPVVVDWSDNYVTLEWSIPKKDGGSPITSYVVE-KKPRYGDWKFAGEFTELFKP 3748 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK-PLKNITTEP 1495 I +L + Y FR AVN+ +SD SE+++ ++ +++ P +K LK++ Sbjct: 3749 HAKITDLVKDEEYEFRICAVNKAGVSDPSESSD--PIVCKSRFVPPHFDKNALKDLIVPV 3806 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 + I P TW RDG + + + Y N Y I Sbjct: 3807 GKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLI 3866 Query: 1552 AFNDHGEVETSCVVGIQQKP--------VITISNEDIKQKHKV----GDEWLVTAVIEGI 1599 N GE S V + KP + I+ E + K+ G + VIE + Sbjct: 3867 VKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEKM 3926 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 W G E + K R+K + S+ +E+S+ V Sbjct: 3927 DMSRGTWSAAGMSTSLANEISRLIHNKRYSFRVKAVNEIGESE-PLESSHPI------VA 3979 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 +++PS+P P ++ + SV++EW P DGG +T+Y ++K E D+ W V Sbjct: 3980 KNDFEEPSQPPKPQVV-DWDANSVSLEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRV 4038 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 + L E+ FRVIA N G SE ++ V+ + + + Sbjct: 4039 PGIQRNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVV 4098 Query: 1780 DNESVY--ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTY 1835 ++ F E +P + + + K + + ++ N + Sbjct: 4099 KAGLIFHLDVNFTGEP---APEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSG 4155 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 +++ N GT +T+ PP P N+ E T +SVT+ W P+ NGGS Sbjct: 4156 DYKLKISNSSGTD---EGSLHLTVLDRPDPPEGPMNY--EEITEKSVTISWKPPKDNGGS 4210 Query: 1896 PITNYIIEFKTV-KGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTE 1953 IT Y++E K + G W V + H + + + ++ FR+ AEN G S Sbjct: 4211 EITGYVVEKKDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLM 4270 Query: 1954 SQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 S+ V + VP PPT P +I + + SW P DGG+ + GYNI RD Sbjct: 4271 SKHPVVAKDQFVVPGPPTKP-DITDSNYDFITLSWKPPISDGGSRISGYNIERRDTATGR 4329 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 W++ K + ++F + H Y R+ A N G +P Sbjct: 4330 WIQANKYPIPNIEFTDTGVMRGHQYDYRVSAVNAAGQGQP 4369 Score = 188 bits (457), Expect = 2e-45 Identities = 210/848 (24%), Positives = 335/848 (39%), Gaps = 80/848 (9%) Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305 +D K ++ + D+ E V+L A + K+EV K + + + + G Sbjct: 1193 ADTGKYKILATNASGKDEAEVELVVLGAPGKCQGKLEVSNVTKKGLKLKWKKPLDDGGCP 1252 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI-YKLRL-- 1362 + N +W+ +C K + A +T D G YK R+ Sbjct: 1253 IKEYKIEKLKNRNGKWV-------RCGTVKGGPEILEADIT-----GLDEGATYKFRVFG 1300 Query: 1363 ENNCGHAD-VEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 N+ G ++ +E + D+P PG+P I++ D+ S+ + W P++ G + I YV+ Sbjct: 1301 VNDEGESEPLESEEVVAKNPFDEPWKPGQPEIVDFDNKSVKLKWAPPKSDGGAPITQYVI 1360 Query: 1418 EYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 + +E +W VK + +T ++++LK N+ +FR AVN+ S S+ T +KV Sbjct: 1361 QKKE-RFKDWEDVKEVPGHETTATVEDLKENTELQFRIVAVNKAGRSPESDPTATHKV-- 1417 Query: 1476 ETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---- 1530 + + P +++ LK I + + G P+P++TW K + A YE Sbjct: 1418 KHRALKPRIDRTNLKPIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPV-FADDHYEIINK 1476 Query: 1531 --NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD 1588 N Y+ IA N+HG + + + P ++K K G Sbjct: 1477 DYNTKFTIKDSMRSKHSGVYEIIAKNEHGMDKEKVEITVLASPSKPKGPLEVKDVTKNGC 1536 Query: 1589 --EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 +W G P K K+ T + T + L+ K+ ++ Sbjct: 1537 KLKWKKPEDDGGKPITGYQLEKYDQKVGRWVPIGKTPGD-TEEFDVTGLQEGQHYKFRVK 1595 Query: 1647 ASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 A N G T V +DKP P +++ + SVT++WK P DGG ++ Sbjct: 1596 AINDEGESEPLETEEYTVAKNPFDKPKAPT-DLVINDWDNSSVTLQWKRPSSDGGAPISG 1654 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES----- 1755 Y IEK E +W I L E Y FRV A N G EA + Sbjct: 1655 YFIEKKERGETKWEPALTTYSPECQAKIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHT 1714 Query: 1756 ------EPIVIKTALDVPSXXXXXXXXXXIDNE---SVYITWFPSEKNGGSPIIDYKVEI 1806 P + +T L + ID E + + WF +K + DYK++ Sbjct: 1715 VKHRYLRPRIDRTNLTPITIKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTD-ADYKIDN 1773 Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 K+ I + N + ++ I A N G ++ +ITI L+ P Sbjct: 1774 VDYNTKF-----------FIMRGRRNLSGKYTIVATNSQGED---RAEVEITI---LSKP 1816 Query: 1867 SQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P SE LKW P +GG PI Y IE W I S E Sbjct: 1817 GTPEGPLEASEVHKHGCKLKWKPPLDDGGMPIDGYEIEKLDPLTGQW--IPCGQSSTPEA 1874 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVM 1984 I ++E + FR+ A N G S P E +++ + K + PS P P G + V Sbjct: 1875 NISGLQEGKQYKFRVKAFNKEGDSEPLEMETIVIAKDPFSEPSKPGRPTPTDW-GKDFVD 1933 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 W P+ DGGAP+ Y I RD + W + V + + + D+ E H Y R+ A Sbjct: 1934 LEWTKPKSDGGAPITEYIIQKRDKSSRKWQDAATVSGDRTRGTVEDVEEGHEYEFRVIAV 1993 Query: 2045 NEIGLSEP 2052 N+ G SEP Sbjct: 1994 NKAGPSEP 2001 Score = 154 bits (373), Expect = 3e-35 Identities = 132/483 (27%), Positives = 203/483 (42%), Gaps = 24/483 (4%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 VG + +E P W ++G + + + I R YT+ Sbjct: 3806 VGKKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTL 3865 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 N+ G S + V DKPS PEGP+ + I+ E +EWK P DDGG +T Y IEK Sbjct: 3866 IVKNSCGEYSASGHVTVLDKPSPPEGPLRITNITTEGCHLEWKLPKDDGGSPITHYVIEK 3925 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764 + W A + + I +L N Y FRV A N +G SE LE S PIV K Sbjct: 3926 MDMSRGTW-SAAGMSTSLANE-ISRLIHNKRYSFRVKAVNEIGESEPLESSHPIVAKNDF 3983 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXX--XXX 1821 + PS D SV + W + +GG+PI +Y V+ K+ + W Sbjct: 3984 EEPSQPPKPQVVDW-DANSVSLEWNAPKSDGGAPITEYIVQKKEKDSPYWSTAGRVPGIQ 4042 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPP--SQPRNFVVSEST 1878 ++ L+ T ++FR+ A N G S P SD +T + + P + R+ VV Sbjct: 4043 RNLKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGL 4102 Query: 1879 SRSVTLKWT-EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 + + +T EP +P + + K V+ T + VG H + N D Sbjct: 4103 IFHLDVNFTGEP-----APEVVWTLNGKPVESDKRTTMTAVGHHTIVHTV-NCNRGDSGD 4156 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 +++ N+ G T+ S+ L P PP P+ + V SW P+ +GG+ Sbjct: 4157 YKLKISNSSG----TDEGSLHLTV-LDRPDPPEGPMNYEEITEKSVTISWKPPKDNGGSE 4211 Query: 1998 LLGYNIAIRDVTK-TMWM-EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + GY + +D+T W+ V V + L++ + Y R+ A N G S+ L S Sbjct: 4212 ITGYVVEKKDLTHGGGWVPAVAYVSPKYTHTVVPRLNKGNKYEFRVMAENLQGRSDGLMS 4271 Query: 2056 DEP 2058 P Sbjct: 4272 KHP 4274 Score = 132 bits (319), Expect = 1e-28 Identities = 89/292 (30%), Positives = 132/292 (45%), Gaps = 6/292 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW-KXXXXXXXX 1822 +D P+ I ES ++W +GGSPI +Y VE + W K Sbjct: 5169 VDKPTPPIGPLEVSEITPESCTLSWKVPLDDGGSPITNYIVERYEPLGYWTKASSFVRST 5228 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + N Y FR+ A N+ G S P ++ I T P P VS+ + V Sbjct: 5229 HYDNMGMENNKQYSFRVRAENQYGISDPLILEEPIIARYPFTVPDPPNPPRVSDWDASYV 5288 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 T+ W P +GGS I Y E++ V +W + + + + N+ E FR+ A Sbjct: 5289 TVTWERPLMDGGSRIQGYRFEYRDVTDSTWI-VCNFLIKDNSYQVYNLVPGREYEFRVRA 5347 Query: 1943 ENTVGVSLPTESQSVRLEKHA--TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 +N GVS P+ S S R + H T PS P AP I+ VG + V SW P DGG+ + G Sbjct: 5348 QNAAGVSKPSAS-SKRFKIHGKITPPSAPGAPAVIK-VGKSFVDLSWTPPASDGGSRITG 5405 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 Y + RD+ W++ + ++ + I +L E Y R+YA N G+S P Sbjct: 5406 YYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVSPP 5457 Score = 118 bits (284), Expect = 2e-24 Identities = 152/653 (23%), Positives = 255/653 (39%), Gaps = 40/653 (6%) Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKP 1387 TK S +S +EN +++R EN G +D + + I+ + P PP P Sbjct: 5219 TKASSFVRSTHYDNMGMENNKQYSFRVRAENQYGISDPLILEEPIIARYPFTVPDPPNPP 5278 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446 + + D+S + + W+ P G S I Y EY+++ + WI + K + + NL Sbjct: 5279 RVSDWDASYVTVTWERPLMDGGSRIQGYRFEYRDVTDSTWIVCNFLIKDNSYQVYNLVPG 5338 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVI-KETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 Y FR A N +S S +++ +K+ K T +P +K + + Sbjct: 5339 REYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAPGAPAVIKVGKSFVDLSWTPPASD 5398 Query: 1506 GGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG-- 1557 GG ++T Y RD + K N Y + A N++G Sbjct: 5399 GG---SRITGYYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVS 5455 Query: 1558 --EVETSCV-VGIQQKPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNG 1610 ET V +G Q + T E +K+ +G +T G P P W +NG Sbjct: 5456 PPSTETRSVRIGEQ---LDTEKPEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNG 5512 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 ++ + ++ + +K + I + YT EA N G +K+ P Sbjct: 5513 KEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVN 5572 Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730 P + I ++ I+ D +E+ + ++ + IK D D I+ Sbjct: 5573 IPSDVYLIKGDNAKIKLGFS-GDHPMEVN-ISKDREKLVETEHIKYTVFD-DYAVIYIRD 5629 Query: 1731 LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 + ++ + ++ V +N G ++ V T L P + ++W P Sbjct: 5630 VEDSDKGVYLVNFKNDSG---SVSCNVNVHVTGL--PGPPTGPLLISHVTKNMCTVSWKP 5684 Query: 1791 SEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSIN-TTYQFRIYARNEIGTS 1848 + +GG I Y VE + + + W I K I + Y FR+ A NE G Sbjct: 5685 PKYDGGRKITHYVVERRDIKSQHWLIVSNYIKETQLIIKGLIEFSEYLFRVSAVNENGMG 5744 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 P D I PS P ++ E V L+W +P S+GG+ I Y IE + Sbjct: 5745 APLEGADPIKARGPYDLPSPPGIPIIHEVGGDFVNLEWDKPFSDGGTRILGYWIEKREQG 5804 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVRLE 1960 +W ++ TV S+ N+ E FR++A+N VG S SQ V+ E Sbjct: 5805 TDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAAQNEVGCSEFSKASQLVKAE 5857 Score = 111 bits (267), Expect = 2e-22 Identities = 107/448 (23%), Positives = 181/448 (40%), Gaps = 32/448 (7%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDK---PSKPEGPVIMREIS 1679 K + ++ L ++ + A N AG S + K++ K PS P P +++ + Sbjct: 5326 KDNSYQVYNLVPGREYEFRVRAQNAAGVSKPSASSKRFKIHGKITPPSAPGAPAVIK-VG 5384 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 + V + W PP DGG +T Y +E+ + RW+K + + V I L E Y F Sbjct: 5385 KSFVDLSWTPPASDGGSRITGYYVERRDIGGARWVKCNESNIPVTELTITNLIEGGVYEF 5444 Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDV--PSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 RV A N G S + E+ + I LD P +SV +T E +G Sbjct: 5445 RVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGKSVQLT---CEAHGK 5501 Query: 1797 -SPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 P + K+ G ++ I ++ + A N +G ++ T+ Sbjct: 5502 PEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYRDEGDYTCEALNFVG-AIHTTA 5560 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 KI + L + ++ + P S ++E + +K Sbjct: 5561 AVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFSGDHPMEVNISKDREKLVETEHIK----- 5615 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAP 1972 TV I ++++ D+ ++ ++ +N G S S + H T +P PPT P Sbjct: 5616 --YTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSG------SVSCNVNVHVTGLPGPPTGP 5667 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 L I V N+ SW P++DGG + Y + RD+ W+ V + + I+ L Sbjct: 5668 LLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIVSNY-IKETQLIIKGLI 5726 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060 E Y+ R+ A NE G+ PLE +P K Sbjct: 5727 EFSEYLFRVSAVNENGMGAPLEGADPIK 5754 Score = 106 bits (255), Expect = 6e-21 Identities = 62/188 (32%), Positives = 94/188 (50%), Gaps = 5/188 (2%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 PP+ P ++S T T+ W P+ +GG IT+Y++E + +K + W IV+ + Sbjct: 5663 PPTGP--LLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWL-IVSNYIKETQ 5719 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 I+ + E E +FR+SA N G+ P E + ++ +PSPP P+ I VG + V Sbjct: 5720 LIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSPPGIPI-IHEVGGDFV 5778 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 W P DGG +LGY I R+ W V V + N +L E Y R+ A Sbjct: 5779 NLEWDKPFSDGGTRILGYWIEKREQGTDTWQRVNTVSCSICTINCPNLVEGRFYEFRVAA 5838 Query: 2044 RNEIGLSE 2051 +NE+G SE Sbjct: 5839 QNEVGCSE 5846 Score = 105 bits (252), Expect = 1e-20 Identities = 121/479 (25%), Positives = 206/479 (43%), Gaps = 44/479 (9%) Query: 726 KIKTGEKEPPQVIEPLKSMIVRQG-ESVILSAQVVGNPRPTITWCKNNKPVKALPT---K 781 ++K E++ PL + ++G E ++ P W + P K Sbjct: 153 QLKKVERKQDTFSRPLVDITCKEGREKKVIFECAFTKPNAKAKWMLRKDEIFTGPKYKFK 212 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 ++GD +S I+ P KV+D G YT++ GI+ A +TVEE A+P + +F + Sbjct: 213 TEGDVYSCLIINP-KVEDSGKYTIEI---AGIS-CFAYLTVEE-----ADP---VYKFTK 259 Query: 842 ITVK-EKGTI----KLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITN 894 K EKG I L V + P W ++ + E I ++ +G + L+I N Sbjct: 260 TLKKNEKGFITHDTHLECAVDNSLAPISWWKGETKLENDGEKYVIGKDLNG-TVTLIIKN 318 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 E D+ Y C K+ ++ I F K L KS + TV L C+ H Sbjct: 319 SVLE-DADTYTCKIEKQTDKTE--TKLKILEYNYKFTKVL-KSQQLFVKDTVTLACELDH 374 Query: 955 TVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 + T +W+ ++I D +II++GR D G+ +C+ +T + VK Sbjct: 375 VLGTVEWFKGDEKIVESDKVQIIKDGRKHKLVLKDVAKADSGMYRCVSNADKTEAEIFVK 434 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH-IR 1072 +F++KL+D E +L++++ E ADV + GE K ++ D G Sbjct: 435 RP-NKFMKKLKDTTGDETKECVLDIQVQDEEADVQFFL-GETEIVKNDRIDIVSPGDGTW 492 Query: 1073 KLYIRNTSVHDEGEYSCIL--RDESCTAEVT------VVELPPEIITRLQNQKVNKGNKA 1124 KL + + D GE +C+ CT +V E+PP++ T + +KV + Sbjct: 493 KLVYKKLELGDAGEITCVCGPLTSKCTLKVNKKETKPKFEVPPKVETPAKVEKVLEVPFT 552 Query: 1125 TFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 T E +K A V FK G + + + ++ K LK + D+GE+ + N+ Sbjct: 553 TGESRQSKVTAKV--FKVGKPVT-PAEVDIVVENDKLVLKFKKTEFQDSGEFKIVLENA 608 Score = 105 bits (252), Expect = 1e-20 Identities = 71/291 (24%), Positives = 120/291 (41%), Gaps = 14/291 (4%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVE 1285 +TW+K I ++ + SD L I +D EYTC ++ K +++ Sbjct: 5896 ITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKSTKASLIIK 5955 Query: 1286 FPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 PPK+ + +R G ++ + + + FP+P W + + I+ H + Sbjct: 5956 SPPKL-NVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETRER 6014 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 LTI+ D+G Y + +EN G ++ + I D P P + +I + + W Sbjct: 6015 HTVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKPRNLTVDQIGLDHVTLSW 6074 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 P G ++I Y+VE +E+ + WI Q I +L Y FR +A N Sbjct: 6075 LPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQLIIPHLSPGHQYEFRVFAENVYGR 6134 Query: 1462 SDASETTEY-------YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 S+ S+ TE K K K + KP + EP D + T +F Sbjct: 6135 SEPSDQTELVSLKDLGIKPAKRVKYELDENGKPKRQGKREPISDYD-TYVF 6184 Score = 103 bits (248), Expect = 4e-20 Identities = 90/353 (25%), Positives = 152/353 (43%), Gaps = 13/353 (3%) Query: 1138 RWFK-DGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195 RW K + S I + I I+G + ++Y + S E + + L E+P Sbjct: 5417 RWVKCNESNIPVTELTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPE 5476 Query: 1196 INFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + RL +F LVP LT E P+ T W + I +F L S + Sbjct: 5477 --WVKRL-KFSLVPLGKSVQLTCEAHGKPEPTC--RWLRNGKEITHGGQFALESKNGVFS 5531 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 L I T D+ +YTC L+ V + PPK+V+ + + +G + + + + Sbjct: 5532 LHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGF 5591 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 + + + + +H K ++ A + I+ VE++D G+Y + +N+ G Sbjct: 5592 SGDHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDSGSVSC 5651 Query: 1372 EMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 +NV + P PP P ++ + + + W P+ G I +YVVE ++I + W+ V Sbjct: 5652 NVNVHVTGLPGPPTGPLLISHVTKNMCTVSWKPPKYDGGRKITHYVVERRDIKSQHWLIV 5711 Query: 1431 KN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 N I +TQ I+ L S Y FR AVNE + E + K + SP Sbjct: 5712 SNYIKETQLIIKGLIEFSEYLFRVSAVNENGMGAPLEGADPIKARGPYDLPSP 5764 Score = 103 bits (247), Expect = 5e-20 Identities = 79/318 (24%), Positives = 138/318 (43%), Gaps = 26/318 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F ++L+ DG +Q C V G P PQI W + + S + Y +A+L Sbjct: 6802 PKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKS-GIASLR 6860 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I E+FPED+GT+ C AKN+ G S+ +L V+ G ++ Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTG-----------RSGDKKGSMV 6909 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDM 688 + P +K + Y +GS+++++C + P+P ++ WL EI + + D+ Sbjct: 6910 KA--PIINKHTDSGYYKDGSEVVIKCN-ITCPDPFNVIWLHDNREIKNTPDFEYLNDGDV 6966 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L I + GTYT A N+ GE+ + + +KE P + S+ V Sbjct: 6967 YS----LHIPEIFPEDAGTYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLD 7022 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYT 804 G + + + P + W K+ +P+ + + ++ TI K +D G Y Sbjct: 7023 GVKAVFTCETFDAP-TKLEWYKDGEPINESSNRYRFVKKDNKYTFTIAK-CSFEDIGQYQ 7080 Query: 805 LKAENSEGIAETSAVITV 822 ++A +G A S + V Sbjct: 7081 VRAVTRQGDALASFSVNV 7098 Score = 77.8 bits (183), Expect = 3e-12 Identities = 68/283 (24%), Positives = 112/283 (39%), Gaps = 31/283 (10%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 PP F +++ + ++L V+ +P+P I W +N + ++ S+ I + L Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGIASLR 6860 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT------------------FVKH 933 I + E DSG Y C A NS G++S + +DV+KV KH Sbjct: 6861 INELFPE-DSGTYVCTAKNSMGETS--TQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKH 6917 Query: 934 LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 Y ++G V+++C + + W H+ +EI E + +G Sbjct: 6918 TDSGYY-KDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFP 6976 Query: 992 XDVGVIKCIV--KDQE-----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G C K E T T+L ++ P F + V + A+ E Sbjct: 6977 EDAGTYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLDGVKAVFTCETFDAP 7036 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 + W +DGE I N+Y F K+ + I S D G+Y Sbjct: 7037 TKLEWYKDGEPINESSNRYRFVKKDNKYTFTIAKCSFEDIGQY 7079 Score = 77.0 bits (181), Expect = 5e-12 Identities = 61/225 (27%), Positives = 95/225 (42%), Gaps = 32/225 (14%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P V+ L V+F C++ G PRP+ITW + I + MY D D + L Sbjct: 5865 PEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGD-MHHLA 5923 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I +VF EDA +TC A N G S+ LI+++P ++ V Sbjct: 5924 INDVFGEDADEYTCRAVNKGGVKSTKASLIIKSP-----PKLNV---------------- 5962 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 PP F + D G +I ++ P+P W KGE+I + + + H Sbjct: 5963 ---PPRFR---DTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETR-ERH 6015 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734 +VL I + + GTYT+ N G+ + I ++I +P Sbjct: 6016 ---TVLTIRDGSQMDSGTYTITIENELGQDTADIKIQISDCPDKP 6057 Score = 75.8 bits (178), Expect = 1e-11 Identities = 66/260 (25%), Positives = 111/260 (42%), Gaps = 25/260 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F+K+ K +G + L C + P P I W G+++ + I + +S + Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGI---- 6856 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--------TGEKEPPQVIEPL--- 741 + L+I + GTY A N GE S L +K +G+K+ V P+ Sbjct: 6857 ASLRINELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINK 6916 Query: 742 --KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKK 796 S + G V++ + + W +N+ +K P +DGD +S+ I + Sbjct: 6917 HTDSGYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFP 6976 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 +D G YT +A N G + +S ITV E E P F ++V + G + Sbjct: 6977 -EDAGTYTCEAFNKGGESFSSCTITV---LGEQKESPTFAKFPASLSVLD-GVKAVFTCE 7031 Query: 857 TRNPVPSITWYRNNEIISPS 876 T + + WY++ E I+ S Sbjct: 7032 TFDAPTKLEWYKDGEPINES 7051 Score = 73.3 bits (172), Expect = 7e-11 Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 34/220 (15%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSIT 790 P VI P +S +G+S +V+G P +TW NN+ +K + GD + Sbjct: 6529 PRFVIRP-QSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELKQSVKFMKRYAGDDYYF- 6586 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------------------EPT----- 826 I+ K+ D G Y ++AEN G E + V EP+ Sbjct: 6587 IINRVKLDDRGEYIIRAENHYGAREEVIFLNVHPMSKQVPVYKPETHTVRKREPSPRPLW 6646 Query: 827 -EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 EE+ P+F + ++ + T KL+ ++ PVP++ WY+N +S E + DG Sbjct: 6647 QEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHTDG 6706 Query: 886 -ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 +E++ T V DSG+YKCVA N GK+ + V ++ Sbjct: 6707 VVTMEIIDTKVG---DSGEYKCVAINPLGKAETSSVVIVE 6743 Score = 72.1 bits (169), Expect = 2e-10 Identities = 53/196 (27%), Positives = 86/196 (43%), Gaps = 13/196 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789 +PP+V++PL ++ Q +V ++ G PRP ITW K + + SDGD H + Sbjct: 5863 KPPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHL 5922 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG- 848 I +D YT +A N G+ T A + ++ P + N P RF++ + G Sbjct: 5923 AI-NDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPP-----RFRDTAFFDNGE 5976 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKCV 907 I++ T P P W E I + + V+T D S++DSG Y Sbjct: 5977 NIEIKIPFTGFPKPRCHWTLKGEQIESGS--HYHIETRERHTVLTIRDGSQMDSGTYTIT 6034 Query: 908 ASNSAGKSSHGARVTI 923 N G+ + ++ I Sbjct: 6035 IENELGQDTADIKIQI 6050 Score = 70.9 bits (166), Expect = 4e-10 Identities = 60/256 (23%), Positives = 100/256 (39%), Gaps = 18/256 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP+ + LK +I GE + L+ V G+P P I W KN K + + I L+ Sbjct: 6801 PPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLTSSDVIDIKYKSGIASLR 6860 Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEEN----------AEPPLFINRFQE 841 ++ +D G Y A+NS G T + V++ + P+ Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKHTDS 6920 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 K+ + + +T ++ W +N I + DG+ L I + E D+ Sbjct: 6921 GYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFPE-DA 6979 Query: 902 GDYKCVASNSAGKSSHGARVTI---DVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVS 957 G Y C A N G+S +T+ E TF K S +G + C+T Sbjct: 6980 GTYTCEAFNKGGESFSSCTITVLGEQKESPTFAK-FPASLSVLDGVKAVFTCETFDAPTK 7038 Query: 958 TKWYHNKKEISGMDHR 973 +WY + + I+ +R Sbjct: 7039 LEWYKDGEPINESSNR 7054 Score = 62.9 bits (146), Expect = 9e-08 Identities = 52/222 (23%), Positives = 84/222 (37%), Gaps = 19/222 (8%) Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 D T E + + + P K LK++ E ++L C G P P++ W ++G Sbjct: 6780 DARSRQSTRELMPLQSDALMHPPKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNG 6839 Query: 1520 KKLKTAKA---TYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 KKL ++ Y++ Y C A N GE T C + +++ T Sbjct: 6840 KKLTSSDVIDIKYKSGIASLRINELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTG 6899 Query: 1576 SNEDIK---------QKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + D K KH K G E ++ I P VIW + +++N ++ Sbjct: 6900 RSGDKKGSMVKAPIINKHTDSGYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFE 6959 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + I E+ + YT EA N G S T+ V Sbjct: 6960 YLNDGDVYSLHIPEIFPEDAGTYTCEAFNKGGESFSSCTITV 7001 Score = 62.1 bits (144), Expect = 2e-07 Identities = 39/131 (29%), Positives = 62/131 (47%), Gaps = 8/131 (6%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I + + D + I+ EN +G ++ ++++ + P P L + +G + V S Sbjct: 6020 IRDGSQMDSGTYTITIENELG----QDTADIKIQI-SDCPDKPRN-LTVDQIGLDHVTLS 6073 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P WDGGA + Y + R+V + W+ G N L I LS H Y R++A N Sbjct: 6074 WLPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQL--IIPHLSPGHQYEFRVFAENV 6131 Query: 2047 IGLSEPLESDE 2057 G SEP + E Sbjct: 6132 YGRSEPSDQTE 6142 Score = 60.9 bits (141), Expect = 4e-07 Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 8/155 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 LK+ ++ E + V+AVN GE+ S + P+++ PL+ M+V+ G Sbjct: 4045 LKVPDLATETEWEFRVIAVNAAGESEPSDASDAVLTRSRFIAPKIVTPLRDMVVKAGLIF 4104 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 L G P P + W N KPV++ T + H+I D G Y LK NS Sbjct: 4105 HLDVNFTGEPAPEVVWTLNGKPVESDKRTTMTAVGHHTIVHTVNCNRGDSGDYKLKISNS 4164 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 G E S +TV + +PP ++EIT K Sbjct: 4165 SGTDEGSLHLTV----LDRPDPPEGPMNYEEITEK 4195 Score = 60.9 bits (141), Expect = 4e-07 Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 8/117 (6%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + I NE+G T+D KI I P +PRN V + VTL W P +GG+ Sbjct: 6031 YTITIENELGQD---TADIKIQISDC---PDKPRNLTVDQIGLDHVTLSWLPPSWDGGAS 6084 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 ITNYI+E + V +W + T ++ I ++ + FR+ AEN G S P++ Sbjct: 6085 ITNYIVEKREVPLSTWIRAGTT--RFNQLIIPHLSPGHQYEFRVFAENVYGRSEPSD 6139 Score = 60.1 bits (139), Expect = 7e-07 Identities = 62/279 (22%), Positives = 109/279 (39%), Gaps = 30/279 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P+F ++L+D + + L ++ + +VW ++G+ + + D + + I L Sbjct: 6802 PKFTKELKDVIASDGEPLQLNCHVSGDPLPQIVWTKNGKKLT-SSDVIDIKYKSGIASLR 6860 Query: 1076 IRNTSVHDEGEYSCILRDE------SCTAEVTVVE-------------LPPEIITRLQNQ 1116 I D G Y C ++ C +V V + II + + Sbjct: 6861 INELFPEDSGTYVCTAKNSMGETSTQCKLDVKKVAGSTGRSGDKKGSMVKAPIINKHTDS 6920 Query: 1117 KVNK-GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 K G++ + +T D V W D EI+ + + DG L I + +DAG Sbjct: 6921 GYYKDGSEVVIKCNITCPDPFNVIWLHDNREIKNTPDFEYLNDGDVYSLHIPEIFPEDAG 6980 Query: 1175 EYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228 Y+CE N S CT + E+ + P + V A T E D + Sbjct: 6981 TYTCEAFNKGGESFSSCTITVLGEQKESPTFAKFPASLSVLDGVKAVFTCETFDAPTKLE 7040 Query: 1229 WYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 WYK + + E + ++ + K T I KC+ +D +Y Sbjct: 7041 WYKDGEPINESSNRYRFVKKDNKYTFTIAKCSFEDIGQY 7079 Score = 60.1 bits (139), Expect = 7e-07 Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVAT 567 API + + DGS V +C + P P + W IK + DF+ Y +D +V + Sbjct: 6911 APIINKHTDSGYYKDGSEVVIKCNIT-CPDPFNVIWLHDNREIKNTPDFE-YLNDGDVYS 6968 Query: 568 LVIREVFPEDAGTFTCVAKNAAG--FASSTTELIVE 601 L I E+FPEDAGT+TC A N G F+S T ++ E Sbjct: 6969 LHIPEIFPEDAGTYTCEAFNKGGESFSSCTITVLGE 7004 Score = 56.4 bits (130), Expect = 8e-06 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 17/278 (6%) Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 + K + E Q+ AP FV + + +G + +F C+V G P +TW+ +K Sbjct: 6512 VTKYKIHETSFDRRQA-APRFVIRPQSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELK 6570 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD----H 607 S F Y D+ +I V +D G + A+N G L V P+S + Sbjct: 6571 QSVKFMKRYAGDDY-YFIINRVKLDDRGEYIIRAENHYGAREEVIFLNVH-PMSKQVPVY 6628 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPP-TFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 E + + P TF+ +P+ + + +L C L P P + Sbjct: 6629 KPETHTVRKREPSPRPLWQEESDAAPVFTFALRPRVMQMRDTCKLL--CCLSGKPVPTVK 6686 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIV 724 W G E+ E + + M +I + K G Y VA+N G E S ++ Sbjct: 6687 WYKNGRELSRYEYSMTHTDGVVTM-----EIIDTKVGDSGEYKCVAINPLGKAETSSVVI 6741 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 ++ + + E PQV +M + + + + +++ +G P Sbjct: 6742 VEDRRHQSELPQVEVTKPTMKIPEPKPLPSASKSLGPP 6779 Score = 55.6 bits (128), Expect = 1e-05 Identities = 56/285 (19%), Positives = 110/285 (38%), Gaps = 11/285 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G+P P++ W+K ++ + Y + + + I ++ + +YT A N G S Sbjct: 5888 ITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHLAINDVFGEDADEYTCRAVNKGGVKS 5947 Query: 1656 VEVTLKVYDKPSKPEGPVIMREIS--RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 + +L + P K P R+ + IE K P + ++ + ++ Sbjct: 5948 TKASL-IIKSPPKLNVPPRFRDTAFFDNGENIEIKIPFTGFPKPRCHWTLKGEQIESGSH 6006 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 + +R I+ ++ + + +N +G A I I D P Sbjct: 6007 YHIETRERHT-VLTIRDGSQMDSGTYTITIENELGQDTA--DIKIQISDCPDKPRNLTVD 6063 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSIN 1832 I + V ++W P +GG+ I +Y VE ++ W I LS Sbjct: 6064 Q----IGLDHVTLSWLPPSWDGGASITNYIVEKREVPLSTWIRAGTTRFNQLIIPHLSPG 6119 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 Y+FR++A N G S P + +++ P++ + + E+ Sbjct: 6120 HQYEFRVFAENVYGRSEPSDQTELVSLKDLGIKPAKRVKYELDEN 6164 Score = 54.8 bits (126), Expect = 2e-05 Identities = 56/236 (23%), Positives = 100/236 (42%), Gaps = 16/236 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEK---EPPQVIEPLKSMIVRQGE 750 L ITN+ + + V AVN G + + ++ GE+ E P+ ++ LK +V G+ Sbjct: 5431 LTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVPLGK 5490 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 SV L+ + G P PT W +N K + +S S+ I +DEG YT +A Sbjct: 5491 SVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHI-SNVTYRDEGDYTCEA 5549 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G T+A + + PP +N ++ + + K+ + + + Sbjct: 5550 LNFVGAIHTTAAVKI-------GVPPKLVNIPSDVYLIKGDNAKIKLGFSGDHPMEVNIS 5602 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ E + +E I + + I +V+ + D G Y N +G S V + Sbjct: 5603 KDREKLVETEHIKYTVFDDYAVIYIRDVE-DSDKGVYLVNFKNDSGSVSCNVNVHV 5657 Score = 54.0 bits (124), Expect = 4e-05 Identities = 42/133 (31%), Positives = 61/133 (45%), Gaps = 8/133 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 + ++K+ E + +VAVN+ G E+ K+K +P LK ++VR G+ V Sbjct: 1384 VEDLKENTELQFRIVAVNKAGRSPESDPTATHKVKHRALKPRIDRTNLKPIVVRGGKMVH 1443 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 V G P P ITW KPV A D +T TI + K GVY + A+N Sbjct: 1444 YDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNT-KFTIKDSMRSKHSGVYEIIAKN 1502 Query: 810 SEGIAETSAVITV 822 G+ + ITV Sbjct: 1503 EHGMDKEKVEITV 1515 Score = 52.4 bits (120), Expect = 1e-04 Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 11/184 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP K + ++ C++ +P P I W EI + + DMH Sbjct: 5864 PPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHH-- 5921 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGE 750 L I +V YT AVN+ G S L IK+ K PP+ + + GE Sbjct: 5922 --LAINDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPPRFRD---TAFFDNGE 5976 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAE 808 ++ + G P+P W + +++ + H++ ++ D G YT+ E Sbjct: 5977 NIEIKIPFTGFPKPRCHWTLKGEQIESGSHYHIETRERHTVLTIRDGSQMDSGTYTITIE 6036 Query: 809 NSEG 812 N G Sbjct: 6037 NELG 6040 Score = 51.6 bits (118), Expect = 2e-04 Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 10/181 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + K+ K V G + L C PEP WL G+EI A+ES ++ Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEIT--HGGQFALESKNGVFS- 5531 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I+NV EG YT A+N G +KI PP+++ + + +G++ Sbjct: 5532 -LHISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGV----PPKLVNIPSDVYLIKGDNAK 5586 Query: 754 LSAQVVGNPRPTITWCKN-NKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + G+ + K+ K V+ K + D +++ ++ + D+GVY + +N Sbjct: 5587 IKLGFSGDHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVYLVNFKNDS 5646 Query: 812 G 812 G Sbjct: 5647 G 5647 Score = 48.4 bits (110), Expect = 0.002 Identities = 57/227 (25%), Positives = 104/227 (45%), Gaps = 16/227 (7%) Query: 699 NVKKFQEGTYTVVAVNREGEAS-LPIVLKIKT-GEKEPPQVIEPLKSMIVRQGESVI--- 753 +++K ++ + V A N+EGE++ L +L +KT +PP+ P K + G + Sbjct: 987 HLQKGRKFEFRVKAYNKEGESTPLETLLAVKTVNPYDPPEA--PGKPAVDDYGVDFVELK 1044 Query: 754 LSAQVVGNPRPT---ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT--LKAE 808 +A RP I CKN K + + +T T+ K +K++ VY ++A Sbjct: 1045 WAAPEKDGGRPVTHYIIECKN-KFMTDWGECAKTETPD-TVCKVHGLKEKVVYQFRVRAV 1102 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-Y 867 N G ++ S +N +P + + +T+K ++ V P P I+W + Sbjct: 1103 NKGGTSKPSEPSENHTVKHKNLKPRIDRTNLKNLTIKVGKSMLWSVDVKGEPEPDISWSW 1162 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 R+N ++ SE I + I + D+G YK +A+N++GK Sbjct: 1163 RDNIPLTVSENIKIETGNYHTNFSIKDA-KRADTGKYKILATNASGK 1208 Score = 48.4 bits (110), Expect = 0.002 Identities = 50/234 (21%), Positives = 86/234 (36%), Gaps = 33/234 (14%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +P++ + EG CR++ + P + W +E+ D + + Sbjct: 6529 PRFVIRPQSAFCYEGQSCKFYCRVIGVATPVVTWYHNNQELKQSVKFMKRYAGDDYYFI- 6587 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLK-----------------IKTGEKEP-- 734 I VK G Y + A N G I L ++ E P Sbjct: 6588 ---INRVKLDDRGEYIIRAENHYGAREEVIFLNVHPMSKQVPVYKPETHTVRKREPSPRP 6644 Query: 735 ---------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785 P L+ +++ ++ L + G P PT+ W KN + + Sbjct: 6645 LWQEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHT 6704 Query: 786 THSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838 +T+ + KV D G Y A N G AETS+V+ VE+ ++ P + + + Sbjct: 6705 DGVVTMEIIDTKVGDSGEYKCVAINPLGKAETSSVVIVEDRRHQSELPQVEVTK 6758 Score = 47.6 bits (108), Expect = 0.004 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 11/135 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749 ++ ++ + Q+ + V AVN G A+ PI+ K K +PP++ L + ++ G Sbjct: 3159 EVPDLMEGQKYEFRVRAVNDAGPGAPSNATPPIICKPKN---QPPKIDRTNLIDVRIKAG 3215 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807 +V+ +V G P PT W N + +K D D ++ ++ + G YT++A Sbjct: 3216 NNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYDYNTKITIRSATRGESGTYTIEA 3275 Query: 808 ENSEGIAETSAVITV 822 EN G + +TV Sbjct: 3276 ENENGKDTATVFVTV 3290 Score = 47.6 bits (108), Expect = 0.004 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +V++L+ P G +VQ C+ G P P W R I F + + V +L Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFAL-ESKNGVFSLH 5533 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I V D G +TC A N G +T + + P Sbjct: 5534 ISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVP 5567 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 2/108 (1%) Query: 497 VFEKPTSEEQSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555 + + ++ +++AP K L K G + E V G P PQITW + I +D Sbjct: 2004 ISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLNVEADVTGEPAPQITWELKGKPITGKED 2063 Query: 556 FQMYYDDDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 ++ D+++ T L+IR + D+G + AKN G + EL+V A Sbjct: 2064 ERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKNKNGTDTVEMELVVLA 2111 Score = 46.8 bits (106), Expect = 0.007 Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 11/135 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQG 749 KIT++ K +E + + AVN+ G E+S PIV K + PP + LK +IV G Sbjct: 3751 KITDLVKDEEYEFRICAVNKAGVSDPSESSDPIVCKSRF---VPPHFDKNALKDLIVPVG 3807 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDE-GVYTLKA 807 + + + V +P T TW ++ + ++ + + +++ P ++++ G+YTL Sbjct: 3808 KKIAYNVTVEASPNVTATWKRDGVVIPESQRVIREAYNNEVSLEIPFSIREDCGMYTLIV 3867 Query: 808 ENSEGIAETSAVITV 822 +NS G S +TV Sbjct: 3868 KNSCGEYSASGHVTV 3882 Score = 46.8 bits (106), Expect = 0.007 Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 8/136 (5%) Query: 698 TNVKKFQEGTYTVVAVNR--EGEASLPIV-LKIKTGEKEPPQVIEPL--KSMIVRQGESV 752 T V + + Y V AVN +G+ S P K ++ P ++ +++ VR GE + Sbjct: 4346 TGVMRGHQYDYRVSAVNAAGQGQPSDPSSKCWAKPMQQAPKLNLDSFGKRTIKVRAGEPI 4405 Query: 753 ILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 I++ +VG P PT+ W +N P + T H++ ++ + KD Y +KA N Sbjct: 4406 IITIPLVGAPIPTVEWFRNGVKIPETSRTTIDTNSEHTVFRVERSERKDSDTYKIKASNQ 4465 Query: 811 EG-IAETSAVITVEEP 825 G VI V+ P Sbjct: 4466 YGEDTREFEVIVVDRP 4481 Score = 45.6 bits (103), Expect = 0.015 Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 12/138 (8%) Query: 700 VKKFQEGT---YTVVAVNREGEASL-PIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVI 753 V+ EGT + V AVN+ G + P+ + ++ P I+ LK+M ++ G+S+ Sbjct: 2274 VQDLFEGTTYQFRVKAVNKGGPSPYSPLSDPVLVKDRFAPPRIDRSTLKNMTLKGGQSLR 2333 Query: 754 LSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L ++ G P PT W N V+ + + + +TI + + G Y +KAEN Sbjct: 2334 LDCKISGEPAPTKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGVTRAHN-GTYEIKAEN 2392 Query: 810 SEGIAETSAVITV-EEPT 826 S G E ITV ++PT Sbjct: 2393 SSGYDEHQFTITVLDKPT 2410 Score = 45.2 bits (102), Expect = 0.020 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P P V WYKNG +L EY++T + + I + K S +Y A N G + Sbjct: 6677 LSGKPVPTVKWYKNGRELSR-YEYSMTHTDGVVTMEIIDTKVGDSGEYKCVAINPLGKAE 6735 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 + V D+ + E P + E+++ ++ I PL L Sbjct: 6736 TSSVVIVEDRRHQSELPQV--EVTKPTMKIPEPKPLPSASKSL 6776 Score = 44.4 bits (100), Expect = 0.035 Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 7/123 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIV---LKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 + +V++ E + V+AVN+ G + + + K P + L ++R G+ + Sbjct: 1977 VEDVEEGHEYEFRVIAVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLN 2036 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAEN 809 + A V G P P ITW KP+ + + D + I++ K D G+Y + A+N Sbjct: 2037 VEADVTGEPAPQITWELKGKPITGKEDERIRLDNEDYKTNLIIRNLKRSDSGIYKVTAKN 2096 Query: 810 SEG 812 G Sbjct: 2097 KNG 2099 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 2/90 (2%) Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA-TLVIREVF 574 ++P G T+++ Q G P P++ W + +I + + D ++ A TL +R Sbjct: 834 IKPITLKKGQTIRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTIDVESCATTLNVRHSV 893 Query: 575 PEDAGTFTCVAKNAAG-FASSTTELIVEAP 603 D+GT+ KN++G F ++ L+++ P Sbjct: 894 RADSGTYKLKLKNSSGEFVTAAKVLVLDVP 923 Score = 44.0 bits (99), Expect = 0.046 Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 6/136 (4%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749 +V K+ +K+ + V AVN+ G + S P + P++ LK++ ++ G Sbjct: 1082 TVCKVHGLKEKVVYQFRVRAVNKGGTSKPSEPSENHTVKHKNLKPRIDRTNLKNLTIKVG 1141 Query: 750 ESVILSAQVVGNPRPTITWC-KNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLK 806 +S++ S V G P P I+W ++N P+ G+ H+ +K K D G Y + Sbjct: 1142 KSMLWSVDVKGEPEPDISWSWRDNIPLTVSENIKIETGNYHTNFSIKDAKRADTGKYKIL 1201 Query: 807 AENSEGIAETSAVITV 822 A N+ G E + V Sbjct: 1202 ATNASGKDEAEVELVV 1217 Score = 43.6 bits (98), Expect = 0.061 Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 11/135 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749 K+T + + + + V AVN G + S PI K + K PP++ LK++ V G Sbjct: 2569 KVTELNEGEVYEFKVRAVNEAGPGVWSDHSKPITAKPR---KLPPKIDRRNLKNLSVAIG 2625 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPK-KVKDEGVYTLKA 807 E ++ G P P + W N++ V T++ D ++ +D G Y +KA Sbjct: 2626 EPFGFDVKISGEPAPDVDWTINDRMVTVTTTRTIDNVPYNSKFANTNPDRRDSGKYVIKA 2685 Query: 808 ENSEGIAETSAVITV 822 N G + +TV Sbjct: 2686 TNKFGTDQVEITVTV 2700 Score = 42.7 bits (96), Expect = 0.11 Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 3/99 (3%) Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---EN 1531 +E +P L+ + + +L C G P P V WY++G++L + + + Sbjct: 6647 QEESDAAPVFTFALRPRVMQMRDTCKLLCCLSGKPVPTVKWYKNGRELSRYEYSMTHTDG 6706 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 YKC+A N G+ ETS VV ++ + Sbjct: 6707 VVTMEIIDTKVGDSGEYKCVAINPLGKAETSSVVIVEDR 6745 Score = 42.3 bits (95), Expect = 0.14 Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 18/209 (8%) Query: 633 PPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP + K + G + L+C++ P P WL + D N + +E Y Sbjct: 2313 PPRIDRSTLKNMTLKGGQSLRLDCKISGEPAPTKYWLLNKARVEKD-NPEIRVE--FEDY 2369 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGE 750 + L I V + GTY + A N G + + +P PLK S + ++G Sbjct: 2370 RAKLTIGGVTRAHNGTYEIKAENSSGYDEHQFTITVL---DKPTAPEGPLKVSNVHKEGC 2426 Query: 751 SVILSAQV--VGNPRPTITWCKNNKPV-KALPTKSDGDTH-SITILKPKKVKDEGVYTLK 806 S+ + + G P K +K + +P DTH +T L+P + E ++ + Sbjct: 2427 SLKWNPPLDDGGVPIDHYNVEKFDKETGRWVPVGRTPDTHMDVTNLEPGQ---EYLFRVS 2483 Query: 807 AENSEGIAE---TSAVITVEEPTEENAEP 832 A N EG++E T I + P +E +P Sbjct: 2484 AVNDEGVSEPLSTEQFIMAKNPFDEPGKP 2512 Score = 42.3 bits (95), Expect = 0.14 Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 6/165 (3%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075 PE++++L+ V L E + + W R+G+ I ++ E + + L+ Sbjct: 5475 PEWVKRLKFSLVPLGKSVQLTCEAHGKPEPTCRWLRNGKEIT-HGGQFALESKNGVFSLH 5533 Query: 1076 IRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132 I N + DEG+Y+C + T + +PP+++ + + KG+ A ++ + Sbjct: 5534 ISNVTYRDEGDYTCEALNFVGAIHTTAAVKIGVPPKLVNIPSDVYLIKGDNAKIKLGFSG 5593 Query: 1133 GDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 + V KD ++ + HI+ T+ + I D + D G Y Sbjct: 5594 DHPMEVNISKDREKLVETEHIKYTVFDDYAVIYIRDVEDSDKGVY 5638 Score = 41.9 bits (94), Expect = 0.19 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 4/140 (2%) Query: 789 ITILKPKKVKDEGVYTLK--AENSEGIAETSAVI-TVEEPTEENAEPPLFINRFQEITVK 845 +T L + + GVY + A N+ G++ S +V + + E P ++ R + V Sbjct: 5428 VTELTITNLIEGGVYEFRVYAVNNYGVSPPSTETRSVRIGEQLDTEKPEWVKRLKFSLVP 5487 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 +++L P P+ W RN + I+ L I+NV D GDY Sbjct: 5488 LGKSVQLTCEAHGKPEPTCRWLRNGKEITHGGQFALESKNGVFSLHISNVTYR-DEGDYT 5546 Query: 906 CVASNSAGKSSHGARVTIDV 925 C A N G A V I V Sbjct: 5547 CEALNFVGAIHTTAAVKIGV 5566 Score = 41.5 bits (93), Expect = 0.25 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 6/148 (4%) Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIE-PLKSMIVRQGESVILSAQVVGN 761 E + V+AVN+ G++ + T + PP++ ++ + + G + V G Sbjct: 2874 EYQFRVIAVNKAGQSDPSDASRTFTAKPRFAPPKIDRRTIRDISISAGSMLKFDVNVSGE 2933 Query: 762 PRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P P W N V + + D +S IL+P D G Y + A NS G Sbjct: 2934 PAPKCEWRVNKATVSSDRRLEILNTDYNSKFILRPANRNDSGDYEITATNSSGRDYVCVQ 2993 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEK 847 +TV + E PL ++ + T K K Sbjct: 2994 VTVTDKPGA-PEGPLQVSDVTKETCKLK 3020 Score = 41.1 bits (92), Expect = 0.33 Identities = 21/87 (24%), Positives = 38/87 (43%) Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575 L+P G V ++ V+G P P+ITW + + +++ D N + + Sbjct: 1431 LKPIVVRGGKMVHYDVNVKGEPEPEITWVLKEKPVFADDHYEIINKDYNTKFTIKDSMRS 1490 Query: 576 EDAGTFTCVAKNAAGFASSTTELIVEA 602 + +G + +AKN G E+ V A Sbjct: 1491 KHSGVYEIIAKNEHGMDKEKVEITVLA 1517 Score = 40.7 bits (91), Expect = 0.43 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 5/95 (5%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + +E + P P I W KG+ I E+ + ++++ Y + L I N+K+ G Sbjct: 2032 GQLLNVEADVTGEPAPQITWELKGKPITGKEDERIRLDNED--YKTNLIIRNLKRSDSGI 2089 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 Y V A N+ G ++ + L + +P + + PLK Sbjct: 2090 YKVTAKNKNGTDTVEMELVVLA---KPSKCMGPLK 2121 Score = 40.7 bits (91), Expect = 0.43 Identities = 42/195 (21%), Positives = 75/195 (38%), Gaps = 13/195 (6%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PPE++ L + F ++T + W K EI + + DG L Sbjct: 5864 PPEVVKPLNTLTCVQNRNVEFVCKITGVPRPKITWHKGAREICSGSRYYMYSDGDMHHLA 5923 Query: 1165 IYDCDLDDAGEYSCEV---GNSKCT--AILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 I D +DA EY+C G K T +++ P +N R + + + ++ Sbjct: 5924 INDVFGEDADEYTCRAVNKGGVKSTKASLIIKSPPKLNVPPRFRDTAFF--DNGENIEIK 5981 Query: 1220 IPDETLD---VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AK 1274 IP W K IE + + + + L IR ++ D YT + + + Sbjct: 5982 IPFTGFPKPRCHWTLKGEQIESGSHYHIETRERHTVLTIRDGSQMDSGTYTITIENELGQ 6041 Query: 1275 STTKLKVEVVEFPPK 1289 T +K+++ + P K Sbjct: 6042 DTADIKIQISDCPDK 6056 Score = 39.9 bits (89), Expect = 0.75 Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 1/125 (0%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +E + + A N G ++ S A P + ++I++ +K V+ Sbjct: 2873 NEYQFRVIAVNKAGQSDPSDASRTFTAKPRFAPPKIDRRTIRDISISAGSMLKFDVNVSG 2932 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P W N +S + N + ++ + DSGDY+ A+NS+G+ Sbjct: 2933 EPAPKCEWRVNKATVSSDRRLEILNTDYNSKFILRPANRN-DSGDYEITATNSSGRDYVC 2991 Query: 919 ARVTI 923 +VT+ Sbjct: 2992 VQVTV 2996 Score = 39.5 bits (88), Expect = 0.99 Identities = 35/139 (25%), Positives = 55/139 (39%), Gaps = 3/139 (2%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N G +E S + N P + + ++ + + A VT P P ITW Sbjct: 1992 AVNKAGPSEPSDISDSVVAKPRNLAPRIDRKNLDKKVLRFGQLLNVEADVTGEPAPQITW 2051 Query: 867 YRNNEIISPSETITQNFDGENIE--LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + I+ E D E+ + L+I N+ DSG YK A N G + + + Sbjct: 2052 ELKGKPITGKEDERIRLDNEDYKTNLIIRNL-KRSDSGIYKVTAKNKNGTDTVEMELVVL 2110 Query: 925 VEKVTFVKHLQKSYETEEG 943 + + L+ S T EG Sbjct: 2111 AKPSKCMGPLKVSDVTAEG 2129 Score = 39.5 bits (88), Expect = 0.99 Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 2/112 (1%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + L A N G ++ S E+ +P + + ++ITV+ + T P P Sbjct: 4753 FRLIAVNDIGSSDPSRPSISVILQEQPNKPMMDLRNVRDITVRAGEDFNIHIPYTAFPKP 4812 Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 TW+ N+E + +T + Q E V+TN DS Y+ + N +G Sbjct: 4813 VATWFANDEQLDDKDTRVHQQLTDEAAIFVVTN-SKRTDSKQYRLMLKNPSG 4863 Score = 39.5 bits (88), Expect = 0.99 Identities = 55/248 (22%), Positives = 96/248 (38%), Gaps = 12/248 (4%) Query: 691 YCSV--LKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 YC+ LKI N++ Q+ + V A N+ G E + + K P Q P + Sbjct: 4929 YCTTTYLKIRNLRINQQYEFRVYAENKYGMSEPAQSDTIIAKHPFDVPTQPGTPTRVETT 4988 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKD--EGVY 803 ++ P + +P + TK T + K + + E ++ Sbjct: 4989 EDSVTITWIKPASNGGSPITHYIVEKRPAAEGTWTKVQQGTLKDLMCKVSGLTENREYIF 5048 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVP 862 + A N+ G + SA T P + + ++I V + K++ + +P P Sbjct: 5049 RVAAVNAAGQSPFSAASDPIMVTAAFTAPKITSDIGMRDILVIARDPFKIIVPFSASPRP 5108 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARV 921 W N +S +E I + E + N +++ +DSG Y N GK S RV Sbjct: 5109 DAFWLVNGNEVSRNERI--ELQVTDTEAIFKNDNAKRLDSGSYTIHLVNCVGKDSASCRV 5166 Query: 922 TIDVEKVT 929 + V+K T Sbjct: 5167 LV-VDKPT 5173 Score = 38.7 bits (86), Expect = 1.7 Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 11/141 (7%) Query: 698 TNVKKFQEGT---YTVVAVNREGEA---SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 T VK G + V A N+ GE+ + LKI+ +P + +K + +++G++ Sbjct: 785 TTVKNLTVGETFEFRVKATNQGGESKPSNSTEPLKIRDRYVKPFIEGDGIKPITLKKGQT 844 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVK-DEGVYTLKA 807 + Q G P P + W K++ + K D ++ + T+ V+ D G Y LK Sbjct: 845 IRYYVQYGGEPEPEVVWEKDDILIICDSEKRKTIDVESCATTLNVRHSVRADSGTYKLKL 904 Query: 808 ENSEGIAETSA-VITVEEPTE 827 +NS G T+A V+ ++ P++ Sbjct: 905 KNSSGEFVTAAKVLVLDVPSQ 925 Score = 38.7 bits (86), Expect = 1.7 Identities = 40/173 (23%), Positives = 73/173 (42%), Gaps = 13/173 (7%) Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLP 722 I + K E+ D N + + SD ++ N+++ +E + ++AVN G + S P Sbjct: 4715 IQYRIKDEDKWIDSNSAADLCSDQSY-----RVENLEENKEYQFRLIAVNDIGSSDPSRP 4769 Query: 723 IVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781 + I + P + + ++ + VR GE + P+P TW N++ + T+ Sbjct: 4770 SISVILQEQPNKPMMDLRNVRDITVRAGEDFNIHIPYTAFPKPVATWFANDEQLDDKDTR 4829 Query: 782 SD---GDTHSITILKPKKVKDEGVYTLKAENSEG--IAETSAVITVEEPTEEN 829 D +I ++ K D Y L +N G IA +A + EN Sbjct: 4830 VHQQLTDEAAIFVVTNSKRTDSKQYRLMLKNPSGYDIATCNAKVLDRPSKPEN 4882 Score = 38.7 bits (86), Expect = 1.7 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 A P PD WL G E+ +E I + + +D ++ K N K+ G+YT+ VN G+ Sbjct: 5104 ASPRPDAFWLVNGNEVSRNERIELQV-TDTE---AIFKNDNAKRLDSGSYTIHLVNCVGK 5159 Query: 719 AS 720 S Sbjct: 5160 DS 5161 Score = 38.3 bits (85), Expect = 2.3 Identities = 51/241 (21%), Positives = 98/241 (40%), Gaps = 23/241 (9%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 +T +++ Q + V A+N EGE+ P+ + T K P + +++ ++ ++ Sbjct: 1581 VTGLQEGQHYKFRVKAINDEGESE-PLETEEYTVAKNPFDKPKAPTDLVINDWDNSSVTL 1639 Query: 757 QVVGNPRPTITWCKNNKPVKA--LPTKSDGDTH---SITILKPK---KVKD---EGVYTL 805 Q RP+ P+ + K G+T ++T P+ K+ D + Y Sbjct: 1640 QW---KRPS---SDGGAPISGYFIEKKERGETKWEPALTTYSPECQAKIPDLPEKRTYQF 1693 Query: 806 K--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + A N G E S P + IT+K +++ + P P+ Sbjct: 1694 RVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTPITIKAGLSVQYDIDIEGEPAPT 1753 Query: 864 ITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W+ + E+++ ++ N D N + I + SG Y VA+NS G+ +T Sbjct: 1754 VKWFHGDKEVVTDADYKIDNVD-YNTKFFIMRGRRNL-SGKYTIVATNSQGEDRAEVEIT 1811 Query: 923 I 923 I Sbjct: 1812 I 1812 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575 L P G +VQ++ +EG P P + WF + D+++ D N ++R Sbjct: 1729 LTPITIKAGLSVQYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRG-RR 1787 Query: 576 EDAGTFTCVAKNAAGFASSTTELIV 600 +G +T VA N+ G + E+ + Sbjct: 1788 NLSGKYTIVATNSQGEDRAEVEITI 1812 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/122 (22%), Positives = 54/122 (44%), Gaps = 2/122 (1%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + +KA N G + S + + A P + + + +T+K +++L +++ P P Sbjct: 2285 FRVKAVNKGGPSPYSPLSDPVLVKDRFAPPRIDRSTLKNMTLKGGQSLRLDCKISGEPAP 2344 Query: 863 SITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 + W N + + I F+ +L I V + +G Y+ A NS+G H + Sbjct: 2345 TKYWLLNKARVEKDNPEIRVEFEDYRAKLTIGGV-TRAHNGTYEIKAENSSGYDEHQFTI 2403 Query: 922 TI 923 T+ Sbjct: 2404 TV 2405 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V F+ +V G P P W +K ++ F++ D D + IR ++GT+T Sbjct: 3215 GNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQ-DYDYNTKITIRSATRGESGTYTI 3273 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 A+N G ++T + V S G + V Sbjct: 3274 EAENENGKDTATVFVTVLDVPSPPGGPLKV 3303 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P G + + VE P TW R +I SQ + +N +L I ED G + Sbjct: 3805 PVGKKIAYNVTVEASPNVTATWKRDGVVIPESQRV-IREAYNNEVSLEIPFSIREDCGMY 3863 Query: 582 TCVAKNAAG-FASSTTELIVEAPLSDHG 608 T + KN+ G +++S +++ P G Sbjct: 3864 TLIVKNSCGEYSASGHVTVLDKPSPPEG 3891 Score = 36.3 bits (80), Expect = 9.2 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 5/132 (3%) Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESV 752 KI ++ + + + V A+N+ G EAS P P++ L + ++ G SV Sbjct: 1681 KIPDLPEKRTYQFRVSAINKAGTGEASDPTGFHTVKHRYLRPRIDRTNLTPITIKAGLSV 1740 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDG-DTHSITILKPKKVKDEGVYTLKAENS 810 + G P PT+ W +K V K D D ++ + + G YT+ A NS Sbjct: 1741 QYDIDIEGEPAPTVKWFHGDKEVVTDADYKIDNVDYNTKFFIMRGRRNLSGKYTIVATNS 1800 Query: 811 EGIAETSAVITV 822 +G IT+ Sbjct: 1801 QGEDRAEVEITI 1812 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 3/97 (3%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGE 886 +N P + ++ +K + +VT P+P+ W N + +E Q++D Sbjct: 3196 KNQPPKIDRTNLIDVRIKAGNNVVFDVKVTGEPIPTTKWLLNKRELKQNERFKIQDYD-Y 3254 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 N ++ I + + +SG Y A N GK + VT+ Sbjct: 3255 NTKITIRSA-TRGESGTYTIEAENENGKDTATVFVTV 3290 Score = 36.3 bits (80), Expect = 9.2 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 2/86 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T +F+ V+G P P W + +I + ++ Y++ L + +V D+G +T Sbjct: 3512 GLTFEFDVPVQGEPVPAKEWTHKDNMIINTDRVKVVYENYR-TKLRVMDVKRSDSGVYTL 3570 Query: 584 VAKNAAGFASSTTELIV-EAPLSDHG 608 AKN G + ++V + P G Sbjct: 3571 TAKNKNGIDIADVNVVVLDVPAPPEG 3596 >UniRef50_Q4RE92 Cluster: Chromosome undetermined SCAF15134, whole genome shotgun sequence; n=488; root|Rep: Chromosome undetermined SCAF15134, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 10495 Score = 268 bits (656), Expect = 1e-69 Identities = 263/1086 (24%), Positives = 443/1086 (40%), Gaps = 62/1086 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PPTF+K + + G+D L+C++ IAW EI + + Sbjct: 7400 MPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKD----H 7455 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I ++K G Y A N G L +K EPP V G + Sbjct: 7456 SATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVK----EPPTFTVKPDGQDVIPGST 7511 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAE 808 V A G T+ W K +K + + T K D + S+ L+ K D Y + Sbjct: 7512 VSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLE-LQAVKPSDSARYACQVS 7570 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867 N G + +A++ V+EP P F+ + + T+ G + +L R T +PV W+ Sbjct: 7571 NDAGKVDCTALLFVKEP-------PTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWF 7623 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ I+P T D L I + +SGDY CVAS+ AG VT+ Sbjct: 7624 KDEMEITPGPKYTMAADDLVASLEIVQC-TLAESGDYVCVASSEAGSDCCRGTVTVKAPP 7682 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXX 985 +FV+ L+ S + +G ++LE Q S + + N K I I + Sbjct: 7683 -SFVRSLE-SKDVVKGSELMLEGQVSGSAPFTVTLCKNGKAIRNDKRHRITVKDELIALQ 7740 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE-VKEKDVAILEVEIN 1041 DVG+ +C V++Q T+ P F++KL++ + +V++L V Sbjct: 7741 VLAVEAGDVGLYQCTVENQVGRVSCDCHVTLKDPPSFVQKLENLSSLVGSEVSLLCVLKG 7800 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CT 1097 SE V W +D +K ++ + L+I + + G+YSC ++++ C+ Sbjct: 7801 SEPMVVSWMKDNHELKEAEH-IQITYESNTALLHITDVQRNHAGKYSCQAQNQAGSQTCS 7859 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 A +TV E P EI ++ V +G+ AT E + L W K G E+ ++ Sbjct: 7860 ALLTVKE-PAEITDEAKSISVTQGDPATLEARFSGTKPLRAMWIKAGKELISGQRYKVLS 7918 Query: 1157 DGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSI--NFTLRLPEFILVPA 1210 LKI D D GEY S +VG S C LT+ + I +FT +L + + A Sbjct: 7919 TDSSSVLKINKTDKSDGGEYTFRVSNDVGQSSCEVTLTILDQIIPPSFTRKLKQTEGIKA 7978 Query: 1211 NTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 + A+L + + V WYK I+ K L I D YTC+ Sbjct: 7979 SF-AHLECLVSGSLPITVHWYKDDKEIQADHKHKCTFFENVAFLEISDLDSKDGGSYTCI 8037 Query: 1270 LLDAKSTTKLK-VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 + + + +V+ PP I++ + GS V V P +W N K I Sbjct: 8038 AKNKAGAVQCSAILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEI 8097 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 D+ S SL + +++D+G Y+ ++N+ G + + + + P P Sbjct: 8098 LSSADCSVIKDNTSTSLALFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEPPKFTRTPA 8157 Query: 1389 ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446 + + N + E + TG I +Y+ E EI +E + + + + +T Sbjct: 8158 RVSVTRLGQNKVF-ECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSLASLEVCGTETK 8216 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 S + A NE SE+ +KE PT+ K L + L C Sbjct: 8217 DSGLYYCEARNEA----GSESCSMELKVKEI----PTIIKDLAPAELVKDSTAHLECQVT 8268 Query: 1507 GVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXX---XXXXXXYKCIAFNDHGEVETS 1562 G +VTWYRD K++K+ AK ++ Y+C N+ G + Sbjct: 8269 GTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVANEVGSCTSK 8328 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 + +++ P T E+ +G + V+EG P V W K+ N + D + T Sbjct: 8329 ATLKLKEPPTFTKKLENTDTV--LGKMAVFQCVVEGSPTLSVQWQKDDNWILEDPKIERT 8386 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 + ++++I + HS KY+ + N AG + TL V + P E P +++ + Sbjct: 8387 FENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQEPPQITEKPEVIKVTVGDP 8446 Query: 1683 VTIEWK 1688 V+++ K Sbjct: 8447 VSLDCK 8452 Score = 219 bits (534), Expect = 9e-55 Identities = 248/1066 (23%), Positives = 423/1066 (39%), Gaps = 76/1066 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PPTF+ KP Q V GS + + W + +EIV + ++ Sbjct: 7494 PPTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATS---- 7549 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM-IVRQGES 751 S L++ VK Y N G+ +L +K EPP + L++ +V G+S Sbjct: 7550 SSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVK----EPPTFVRKLEATTLVTCGQS 7605 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L + G+P W K+ + P T + D + + + + G Y A + Sbjct: 7606 SRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASS 7665 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G +TV+ P P F+ + V + + L +V+ + ++T +N Sbjct: 7666 EAGSDCCRGTVTVKAP-------PSFVRSLESKDVVKGSELMLEGQVSGSAPFTVTLCKN 7718 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + I + E I L + V++ D G Y+C N G+ S VT+ + + Sbjct: 7719 GKAIRNDKRHRITVKDELIALQVLAVEAG-DVGLYQCTVENQVGRVSCDCHVTLK-DPPS 7776 Query: 930 FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 FV+ L+ + + G V L C + S + W + E+ +H +I E Sbjct: 7777 FVQKLE-NLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITYESNTALLHIT 7835 Query: 988 XXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-S 1042 G C ++Q S +L VKE E + + V + D A LE + + Sbjct: 7836 DVQRNHAGKYSCQAQNQAGSQTCSALLTVKEPA-EITDEAKSISVTQGDPATLEARFSGT 7894 Query: 1043 ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097 + +W + G E+I ++ K + K I T D GEY+ + ++ SC Sbjct: 7895 KPLRAMWIKAGKELISGQRYKVLSTDSSSVLK--INKTDKSDGGEYTFRVSNDVGQSSCE 7952 Query: 1098 AEVTVVE--LPPEIITRLQNQKVNKGNKATF-EIELTKGDAL---VRWFKDGSEIQFSNH 1151 +T+++ +PP +L K +G KA+F +E +L V W+KD EIQ + Sbjct: 7953 VTLTILDQIIPPSFTRKL---KQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQADHK 8009 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 + T L+I D D D G Y+C + G +C+AIL V+EP L PE + Sbjct: 8010 HKCTFFENVAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEPPC--ILEKPESMN 8067 Query: 1208 VPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 V + + V + L + W+K + I + ++I D +L + D EY Sbjct: 8068 VLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSLALFFAKSSDSGEY 8127 Query: 1267 TCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVN 1324 C + D ST+ V+ PPK + R G + P+ + W Sbjct: 8128 RCEIQNDVGSTSCQATLFVKEPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKE 8187 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-- 1382 I + + S + ASL + E D+G+Y N G M + + + P+ Sbjct: 8188 GSEIHPSERYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVKEIPTII 8247 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSI 1440 P L DS++ C + TG S + + + +EI ++ S I T + Sbjct: 8248 KDLAPAELVKDSTAHLEC----QVTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEV 8303 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 ++ NEV + T + +KE PT K L+N T + Sbjct: 8304 HKCGAADVGEYQCTVANEVGSCTSKATLK----LKEP----PTFTKKLENTDTVLGKMAV 8355 Query: 1501 LTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXX-XXXXXXXYKCIAFNDH 1556 C+ G P V W +D + + T+EN Y C N+ Sbjct: 8356 FQCVVEGSPTLSVQWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVNEA 8415 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G+ + S + +Q+ P IT E IK VGD + + G P +V W K G +L++ Sbjct: 8416 GQTKCSATLTVQEPPQITEKPEVIKVT--VGDPVSLDCKVTGSPALKVKWMKEGKELQSI 8473 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +++ + + S ++I+ +R +Y +E +N +S +V L V Sbjct: 8474 RQHKLVFENNISSLKIQAAEREDEGEYILEVANHISRTSCKVRLVV 8519 Score = 213 bits (521), Expect = 3e-53 Identities = 214/862 (24%), Positives = 368/862 (42%), Gaps = 62/862 (7%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP +E+++ K V+F +V G P P+ WF+ +++ ++ ++ +DNV L Sbjct: 1807 APRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCEL 1866 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 VIR+V ED+ + A N AG ASS L+V+ A Sbjct: 1867 VIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAKA 1926 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 A ++ + + EC + P + WL EI + + + + Sbjct: 1927 AVSFTQHLED---ATANEKDTMVTFECE-TSEPFIKVKWLKNNTEIFSGDKYRMHSDRKV 1982 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 H + SVL I +++ + YT V + E + L ++ E + +E ++ Sbjct: 1983 H-FLSVL-IIDLR--DDAEYTCVLADDESVRT-SARLTVEGAALELIKHMENIEVPETYA 2037 Query: 749 GE-SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 GE V LS + V K P S H++++ +K +D+G YT Sbjct: 2038 GEFEVELSREDVEGS--WFFGDKELSPSSKHIMSSRRGRHTLSVKDVRK-EDQGKYTFVC 2094 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 G TSA + ++ P + +++V E +L R ++ V TW Sbjct: 2095 ----GDLRTSASLKMK------LRPVTLMLPLTDLSVCEGDIAQLEVRFSQENVEG-TWM 2143 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ + ISPS+ + D + +L++ NV +E D+ Y V + S+ G + V+ Sbjct: 2144 KSGQAISPSDRVHIVIDKQVHKLLLENVSTE-DAASYSFVVP-AQDISTAGK---LSVQT 2198 Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 + V L K T EG +LE + S S KWYHN K+++ D + + +G Sbjct: 2199 IDIVVPL-KDLSTVEGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLV 2257 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G K +V +TS L V++ ++ ++D E VE++ Sbjct: 2258 FSRTHASDQGQYKLVVGKVDTSCTLTVEKV--HIVKHMEDRVCSESQKVTFRVEVSHPGI 2315 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 D VW +++KP KY E + + L I +T +EG+Y +++ +A +TV Sbjct: 2316 DPVWTVRNQLLKPGA-KYKMESKDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTV--- 2371 Query: 1106 PPEIITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 ITR LQ+ V + A E E+ +A RW K+G + FS ++ + G ++L Sbjct: 2372 SGGAITRPLQDVTVAESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLT 2431 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223 I D GEYS +V NSK TA L VE I TLR V DA T+E+ + Sbjct: 2432 ITITRPQDVGEYSYQVANSKTTANLRVEAVKIKKTLRNQ---TVTETQDAVFTLELTHAD 2488 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 W K ++ ++K+ + SD ++L IR C D+ Y+ L + +L VE Sbjct: 2489 VKGSQWIKNGVELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVET 2548 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVD----YQAFPQPND---EWIVNSKIIKKCKHTKP 1336 ++ IK+ DVT L+D ++ +D +W+ +K K Sbjct: 2549 IKI------------IKKTKDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKI 2596 Query: 1337 SIDSKSASLTIKKVENTDAGIY 1358 + ++ L ++ V +++AG Y Sbjct: 2597 LRERRAHKLILQNVNSSNAGEY 2618 Score = 208 bits (509), Expect = 1e-51 Identities = 194/775 (25%), Positives = 326/775 (42%), Gaps = 41/775 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F +K + GS++ L C L ++W+ E+ E+I + ES+ Sbjct: 7774 PPSFVQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITYESNT---- 7829 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 ++L IT+V++ G Y+ A N+ G + +L +K EP ++ + KS+ V QG+ Sbjct: 7830 ALLHITDVQRNHAGKYSCQAQNQAGSQTCSALLTVK----EPAEITDEAKSISVTQGDPA 7885 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENS 810 L A+ G W K K + + T S ++LK K D G YT + N Sbjct: 7886 TLEARFSGTKPLRAMWIKAGKELISGQRYKVLSTDSSSVLKINKTDKSDGGEYTFRVSND 7945 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G + +T+ + PP F + ++ + L V+ + ++ WY+++ Sbjct: 7946 VGQSSCEVTLTILD----QIIPPSFTRKLKQTEGIKASFAHLECLVSGSLPITVHWYKDD 8001 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + I F L I+++DS+ D G Y C+A N AG A + V++ Sbjct: 8002 KEIQADHKHKCTFFENVAFLEISDLDSK-DGGSYTCIAKNKAGAVQCSAILL--VKEPPC 8058 Query: 931 VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 + +S G V S T ++ KW+ N+KEI +I++ Sbjct: 8059 ILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTSTSLALFF 8118 Query: 989 XXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDV-AILEVEIN-S 1042 D G +C +++ ST L VKE P+F R V + E ++ + Sbjct: 8119 AKSSDSGEYRCEIQNDVGSTSCQATLFVKEP-PKFTRTPARVSVTRLGQNKVFECQVTGT 8177 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTA 1098 DV W ++G I P + +Y + L + T D G Y C R+E SC+ Sbjct: 8178 PEIDVYWFKEGSEIHPSE-RYQMSFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSM 8236 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS-NHIQLTI 1156 E+ V E+P II L ++ K + A E ++T V W++D EI+ S H I Sbjct: 8237 ELKVKEIPT-IIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQI 8295 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS--KCT--AILTVEEPSINFTLRLPEFILVPANT 1212 +G L+++ C D GEY C V N CT A L ++EP FT +L V Sbjct: 8296 NGTLG-LEVHKCGAADVGEYQCTVANEVGSCTSKATLKLKEPP-TFTKKLENTDTVLGKM 8353 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 + V TL V W K + I + K + L I C +Y+C +++ Sbjct: 8354 AVFQCVVEGSPTLSVQWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVN 8413 Query: 1273 AKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 TK + V+ PP+I + ++ G V+L P +W+ K ++ Sbjct: 8414 EAGQTKCSATLTVQEPPQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSI 8473 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + K ++ +SL I+ E D G Y L + N+ ++ + +L + GK Sbjct: 8474 RQHKLVFENNISSLKIQAAEREDEGEYILEVANHISRTSCKVRLVVLVEWQKDGK 8528 Score = 198 bits (484), Expect = 1e-48 Identities = 204/826 (24%), Positives = 341/826 (41%), Gaps = 86/826 (10%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 K T +E P+F KL P+ G +++ EC + G ++TW + I+ ++ + Sbjct: 9482 KLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNIS 9541 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619 D N L I + D G + C A N G S + S++TV Sbjct: 9542 CVD-NTPHLTILKADKGDTGKYFCHAMNDVGKVSCS-------------SDVTVKERKN- 9586 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 PP F+KKP D EG + +E R+ ++W + EI + Sbjct: 9587 -------------PPVFTKKPSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSD 9633 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 ++ +S++ + C +K ++V G YT A N G AS + I +K PP Sbjct: 9634 KYDISFKSNVAVLC--IKSSHVT--DSGRYTCQASNEAGRASCCTTVGISEAKK-PPVFD 9688 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKK 796 PLK + V +GE + L V G+ I W K+ K + + T L+ P Sbjct: 9689 VPLKPLTVDEGEKMSLKCHVCGSAPLIIQWMKDRKELTSGGNTKISFTDGTACLEISPAS 9748 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEE-------PTEENA--------EPPLFINRFQE 841 KD G Y KA N G + A + V + P E A + FI + Sbjct: 9749 RKDAGDYLCKATNDAGSEFSKAKVAVRQKPGAALAPAEAPAVAAPVKRQDNLFFIEEPKA 9808 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEID 900 + V EK T + +V +P+PS+ W + ++ I+ + G+ +L I V + D Sbjct: 9809 VRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGGRISVDQKGQEAKLEIREV-TRSD 9867 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFV----------KHLQKSYETEEGKTVILEC 950 SG Y+C+ASN G+ + + ++ +K + V K K +E K + + Sbjct: 9868 SGQYRCIASNKHGEIECSSDLLVEEKKESAVLEGDLRAKLKKTPSKQKSPKEEKDIDI-V 9926 Query: 951 QTSHTVSTKWYHNKKEISGM-DHREIIQ------------EGRXXXXXXXXXXXXDVGVI 997 + V K Y + G+ D+R ++Q GR D+ + Sbjct: 9927 ELLRNVDPKEYEKYARMYGITDYRGMLQAIEQLKKEKAMESGRPELERAERESDEDMARL 9986 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 ++ + T V T+ I F KE + EV IN + W + + + Sbjct: 9987 VADLQKRMERTEPV---TVLSDISDQSVFTGKEAEFQC-EVTINYPEITLSWYKGTQKLD 10042 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 +KYD G L IR D+G Y + +A++TV+E E+ LQ+ Sbjct: 10043 -SSDKYDISISGDRHLLRIRRCQTSDQGNYRVVCGPHISSAKLTVMEA--EVEKHLQDTS 10099 Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 +G T +L+ + +WFK+G ++ + K QKL I D +D G Y+ Sbjct: 10100 GKEGQSCTLSCQLSIPNVQAQWFKNGKRLEMKGKFTSEVKHKIQKLLISDLKPEDQGRYT 10159 Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237 C+ + + +A L VE I+FT R+ I V A E+ + V+WYK ++ Sbjct: 10160 CQYQSLESSADLWVEAEQIHFTKRIHN-IEVNERQSATFECEVSFDNAIVSWYKDTWELK 10218 Query: 1238 DTEKFTLISDVKKRTLIIRKCT-EDDQCEYTCVLLDAKSTTKLKVE 1282 ++ K+ S+ ++ ++IR T ED++ E V L A+ + VE Sbjct: 10219 ESPKYNFTSEGRRHFMVIRNVTIEDEEIELAMVPLAARVLIEETVE 10264 Score = 197 bits (480), Expect = 3e-48 Identities = 220/1022 (21%), Positives = 405/1022 (39%), Gaps = 58/1022 (5%) Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQ 736 + + V S M S+++ +V + G AV EG A L I+ + Sbjct: 6594 QRLQVTSASRKQMLSSMVETASVAESAAG---FSAVKAEGAALRTESKLTIECAAAQQQV 6650 Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796 V++ K+ +R+ + L + ++ K V+++ KS + ++ P Sbjct: 6651 VVQETKAAAIRESTTSQLRVSTEAAFQQSVQVVKEE--VRSVLVKSREEDVGAAVV-PSA 6707 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 ++ + + + E V+ E E P + ++I+V E L + Sbjct: 6708 TLPTTIHEEETVDISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTI 6767 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 T + W N +++ P + + + + LVI+ V E+ G+Y C A N AGK++ Sbjct: 6768 TH--AAKVNWLFNGQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTT 6825 Query: 917 HGARVTIDVEKVTFVKHLQ-KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHR 973 +R+T+ V +V V L+ + E G + C+ S V+ +WY + EI + Sbjct: 6826 TSSRLTV-VPRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKY 6884 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVK-----DQETSTMLVVKETIPEFIRKLQDFEV 1028 I+ D G C V D ++++V + P F+ K + + Sbjct: 6885 RIVSSSTSSALELVSPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTL 6944 Query: 1029 KEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 A+ + + S DVVW +D I + KY + + L+I++ + +G Y Sbjct: 6945 FVGKEAVFQCSLTGSSPMDVVWHKDNLAIS-SEGKYVMKSDKNKYSLHIQSLELAHQGVY 7003 Query: 1088 SCILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKD 1142 C + TA E+ V++ P + + E ++ + + + W +D Sbjct: 7004 LCKASNSVGTATFSTELWVID-KPSFVKPFDQASAAVNDPVRLECQVNEDTGVTIIWTRD 7062 Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSIN 1197 G ++ S +L+ + K ++I L D+G+Y C E G+S C A++ V+E PSI Sbjct: 7063 GKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSIR 7122 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256 L+ E + AYL EI ++TW K + I +K+ +IS L I Sbjct: 7123 KELQTVEAL---KGGPAYLEYEIAGTAPFEITWSKNRKPITSDKKYNIISQQSLSRLEIL 7179 Query: 1257 KCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314 D +Y V+ + K +TK ++ E PP G+ V L + Sbjct: 7180 TFESADVGDYQMVVSNEVGKVSTKAVAKLKE-PPSFTKRVDSVTAVLGTTVKLQGTVKGS 7238 Query: 1315 PQPNDEWIVNSKIIKKCKHT-KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 +W+ +S+ ++ + + D+ A L+I V + G Y + EN G E Sbjct: 7239 SPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQKSEA 7298 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQE-IDTTEWIS 1429 +T+ +P+ +P ++SI++ E E+T + + V +++ + T Sbjct: 7299 TLTV-QEPARVVEP------AASISVTAGESATLESTISGSPELKVKWFKDGKEMTSGRK 7351 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 K K T+ + + Y + + E T V+ T PT KPL+ Sbjct: 7352 CKMTVKDNTATMKILSAEKSDSAEYIMQVSNKVGKDECTCSLTVLDRT--MPPTFTKPLR 7409 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXX 1545 + D L C G + W++D ++ K ++ Sbjct: 7410 RVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKDHSATLQIAGLEKADS 7469 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 YKC A N G ETS + +++ P T+ + Q G A G P V Sbjct: 7470 GVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDG--QDVIPGSTVSFRAAFTGTAPLTVK 7527 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+K ++ + Y I +S + ++ +K S S++Y + SN AG L V + Sbjct: 7528 WFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSARYACQVSNDAGKVDCTALLFVKEP 7587 Query: 1666 PS 1667 P+ Sbjct: 7588 PT 7589 Score = 195 bits (476), Expect = 1e-47 Identities = 212/983 (21%), Positives = 390/983 (39%), Gaps = 57/983 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789 EPP + + M +G+ V L ++ G +TW K+ KP+ + S+G + ++ Sbjct: 8734 EPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTL 8793 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 I+ + D G Y K NS G ++ + EP P F+ + +TV Sbjct: 8794 HIIGLEST-DIGQYECKVSNSVGSDTCQTLVKLREP-------PSFVKKLSNMTVVLGQE 8845 Query: 850 IKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 + L A V + +++W ++ + I+ + F+ + L + D+ +G Y C Sbjct: 8846 VTLQATVKGSEPITVSWVQDKDHILRDGDNRRITFENNTVTLKVFKADAST-AGRYTCHL 8904 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKE 966 +N AG S A + + +E V + G LE + T + TKW+ + E Sbjct: 8905 TNDAGTSECFANLNV-LEPAKIVDK-PDALSVTAGDIAALEVKVCGTPELVTKWFKDGIE 8962 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVG-----VIKCIVKDQETSTMLVVKETIP-EFI 1020 ++ + +I D G ++ + KD + V+ + IP F Sbjct: 8963 LASGNKYKISFSRMISCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDKIIPPSFS 9022 Query: 1021 RKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 RKL+D +E +++ S + W DGE I+ N Y+ + L + Sbjct: 9023 RKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPN-YEISFSNNSCILRVPTL 9081 Query: 1080 SVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA- 1135 + D G Y C +E+ T+E V+ PP + Q+ + G+ TF + KG A Sbjct: 9082 KLSDSGLYKCKAVNEAGTSETAATMDVKEPPSFVVPPQSLEALPGSNVTFSA-MVKGSAP 9140 Query: 1136 -LVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEV----GNSKCTAIL 1189 ++WF+ E++ ++ Q L++++ D AGEY+C++ G L Sbjct: 9141 LKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQIINDAGKESWPVNL 9200 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 +++EP+ F+ +L + + + V WYK + + K+ I+ + Sbjct: 9201 SIKEPAA-FSKKLKDVSVEKGKPLTLECTYTGTPKITVNWYKDGQQVFASYKYN-ITTTE 9258 Query: 1250 KRTLIIRKCTEDDQC--EYTC-VLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305 ++ T+D + +Y C V DA + T + V ++E PP V+ + G V Sbjct: 9259 SSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSILE-PPYFVESLEPMEVTAGDAV 9317 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 L P+ W ++ + A L + K D G Y + EN Sbjct: 9318 CLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLKLSKATKADIGEYSCKAENR 9377 Query: 1366 CGHADVEMNVTILDKPSPPGKPN-ILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEID 1423 G + +L+ +PP P I + + E G+S I + ++ + + + Sbjct: 9378 IGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGEPLK 9437 Query: 1424 TTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 S+ T I+ + S + A N V T+ K+ + P Sbjct: 9438 AGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSV-----GSTSCRAKLTLQEPRYPP 9492 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXX 1538 ++ L + IEL C G KVTW +D K +++ + +N Sbjct: 9493 VFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNYNISCVDNTPHLTIL 9552 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C A ND G+V S V ++++ P + + G + + Sbjct: 9553 KADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPPVFTKKPSEHMEDTEGRLVKIEGRV 9612 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P V WYK ++ + +Y+I+ K +V+ IK + S +YT +ASN AG +S Sbjct: 9613 SGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSGRYTCQASNEAGRASC 9672 Query: 1657 EVTLKVYDKPSKPEGPVIMREIS 1679 T+ + + P V ++ ++ Sbjct: 9673 CTTVGISEAKKPPVFDVPLKPLT 9695 Score = 194 bits (473), Expect = 2e-47 Identities = 230/1054 (21%), Positives = 403/1054 (38%), Gaps = 63/1054 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 VDE S L + + + WLF G+ + P + + E D + + K+ VK+ Sbjct: 6755 VDEDSKATLSTTITHAAK--VNWLFNGQLVKPGKEFRCSKEKDTYTLV-ISKV--VKEMH 6809 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 +G Y A N G+ + L + + PP + ++ + G S +V P Sbjct: 6810 QGEYVCEAENEAGKTTTSSRLTVV--PRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDV 6867 Query: 765 TITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 W K+ +K S + ++ ++ P K D G Y+ K N G+ +A + Sbjct: 6868 NFRWYKSGVEIKQSEKYRIVSSSTSSALELVSPVKA-DSGEYSCKVSNPHGVDTCAASLI 6926 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V E PP+F+++ + +T+ +T + + W+++N IS Sbjct: 6927 VTE-----LYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVM 6981 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 D L I +++ G Y C ASNS G ++ + + ++K +FVK ++ Sbjct: 6982 KSDKNKYSLHIQSLEL-AHQGVYLCKASNSVGTATFSTELWV-IDKPSFVKPFDQA-SAA 7038 Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 V LECQ + V+ W + K++ ++ E + D G C Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVC 7098 Query: 1000 IVKDQ--ETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEI-NSETADVVWERDGEI 1055 ++ +S VV P IRK LQ E + A LE EI + ++ W ++ + Sbjct: 7099 TATNEAGSSSCEAVVMVQEPPSIRKELQTVEALKGGPAYLEYEIAGTAPFEITWSKNRKP 7158 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITR 1112 I K KY+ + + +L I D G+Y ++ +E T V ++ PP R Sbjct: 7159 ITSDK-KYNIISQQSLSRLEILTFESADVGDYQMVVSNEVGKVSTKAVAKLKEPPSFTKR 7217 Query: 1113 LQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCD 1169 + + G + KG + V+W KD ++ + I LT D L I Sbjct: 7218 VDSVTAVLGTTVKLQ-GTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVA 7276 Query: 1170 LDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DET 1224 + G+Y C E G K A LTV+EP+ + I V A A L I Sbjct: 7277 ISHGGKYVCQAENEAGQQKSEATLTVQEPA--RVVEPAASISVTAGESATLESTISGSPE 7334 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLK 1280 L V W+K + K + T+ I + D EY + + + T L Sbjct: 7335 LKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKSDSAEYIMQVSNKVGKDECTCSLT 7394 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V PP R G+D +L W + I + Sbjct: 7395 VLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAGPKFQAGFKD 7454 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 SA+L I +E D+G+YK R N+ G + + + + P+ KP+ ++ S Sbjct: 7455 HSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPPTFTVKPDGQDVIPGSTVSF 7514 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 T T+ ++ + + + + K+ T + +Q +K + S R+ N+ Sbjct: 7515 RAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSARYACQVSNDAG 7574 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDG 1519 D + +KE PT + L+ T + L C G P W++D Sbjct: 7575 KVDCTALL----FVKE----PPTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKDE 7626 Query: 1520 KKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VI 1573 ++ K A + Y C+A ++ G V ++ P V Sbjct: 7627 MEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPSFVR 7686 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 ++ ++D+ + G E ++ + G P V KNG + NDK + IT K++ +++ Sbjct: 7687 SLESKDVVK----GSELMLEGQVSGSAPFTVTLCKNGKAIRNDKRHRITVKDELIALQVL 7742 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 ++ Y N G S + + + D PS Sbjct: 7743 AVEAGDVGLYQCTVENQVGRVSCDCHVTLKDPPS 7776 Score = 192 bits (467), Expect = 1e-46 Identities = 222/1003 (22%), Positives = 390/1003 (38%), Gaps = 95/1003 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V E +LEC VA E + W+ +G+ + EN+ ++ + L IT + Sbjct: 2385 VAESQTAVLECE-VANAEAEGRWMKEGQPVDFSENVVSEVKGAVRR----LTITITRPQD 2439 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y+ N + A+L + E ++ + L++ V + + + + ++ Sbjct: 2440 VGEYSYQVANSKTTANLRV---------EAVKIKKTLRNQTVTETQDAVFTLELTHADVK 2490 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 W KN +++ SDG S+ I + +DE VY+ K + + SA Sbjct: 2491 GSQWIKNGVELQSSDKYEISSDGMVQSLKI-RNCNTQDESVYSFK------LGKLSANAR 2543 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 + N E I + +++T GT ++ + VP + W + PS+ Sbjct: 2544 L------NVETIKIIKKTKDVTTLMDGTASFEMSLSHDDVP-VKWMFKGAELKPSDRCKI 2596 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + +L++ NV+S ++G+Y V + T+ VE + VK + K Sbjct: 2597 LRERRAHKLILQNVNSS-NAGEYTAVVGHLQ------CSATLTVEALQIVKPM-KDASVA 2648 Query: 942 EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 E + EC+ SH V + W + EI + I+ +G+ D I Sbjct: 2649 ETQAATFECEVSHFNVPSTWLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFI 2708 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 + S L V + L+D +E+D EV +N E W ++G +K Sbjct: 2709 CGNDRVSATLTVSPVL--ITSMLKDLNAQERDTITFEVTVNHEGITYKWLKNGVEVK-SS 2765 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 ++ R L IRN D GEY + + +A + V E ++++ K+ + Sbjct: 2766 DRCQVRSRQLTHTLTIRNVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKIIE 2825 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCE 1179 KA FE E+++ + V W KDG E+ S +T K +L I + DAGEYS Sbjct: 2826 KKKAIFECEVSEPNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVV 2885 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 G+S A L VE I I V A + E+ ++ ++ W K + + Sbjct: 2886 AGSSVSKAQLVVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNGAELSLE 2945 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299 E+F+ + K + I + D EYT + +S+ L+V + E PP+I+ + + Sbjct: 2946 ERFSYVVIRKVHRITISETFRSDAGEYTFIAGKNRSSVNLRVNIPE-PPQILRHMEPQSV 3004 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + G V+ PQP W NS+++ K ++ SL + +V DA +Y Sbjct: 3005 EVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYS 3064 Query: 1360 LRLENNCGHAD--VEMNVTILDKPSP----PGKPNILEIDSSSINICWDEPEN-----TG 1408 +N+ G A +NV + + SP P ++ SS + EP G Sbjct: 3065 CEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHG 3124 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 + I + + +EI +E+ + + Q I + + A N + S T Sbjct: 3125 DDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSAT 3184 Query: 1468 ---------------------TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 T + K Q PT +P+++ T Sbjct: 3185 LTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPIRSCTVAHGAVARFHACVS 3244 Query: 1507 GVPQPKVTWYRDGKKLK-TAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G+P+P+V+W+ + + ++ T + N Y C A N GE Sbjct: 3245 GMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSAGEAA 3304 Query: 1561 TSC---VVGIQQKPVITIS-------NEDIKQK-HKVGDEWLV 1592 S + +QQ+ V + +DIK+ H G E LV Sbjct: 3305 CSATLTITKVQQEEVTVVKEQTQIQIQQDIKEPFHGSGSEELV 3347 Score = 186 bits (453), Expect = 6e-45 Identities = 181/781 (23%), Positives = 317/781 (40%), Gaps = 50/781 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 IPP+FS+K K + G +EC++ P I+W GEEI N ++ ++ Sbjct: 9017 IPPSFSRKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNS--- 9073 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 C +L++ +K G Y AVN G + + + KEPP + P +S+ G + Sbjct: 9074 C-ILRVPTLKLSDSGLYKCKAVNEAGTSETAATMDV----KEPPSFVVPPQSLEALPGSN 9128 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLKAE 808 V SA V G+ + W + K ++ T S T + ++ D G YT + Sbjct: 9129 VTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLELFNVDRSHAGEYTCQII 9188 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G ++++EP F + ++++V++ + L T P ++ WY+ Sbjct: 9189 NDAGKESWPVNLSIKEPA-------AFSKKLKDVSVEKGKPLTLECTYTGTPKITVNWYK 9241 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + + S + L + D + +G Y C SN AG+ + A V+I +E Sbjct: 9242 DGQQVFASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSI-LEPP 9300 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 FV+ L+ E G V L+C+ + T + W+ ++ + Sbjct: 9301 YFVESLE-PMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLKL 9359 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040 D+G C +++ +S L V E T P F +K+ + E E I Sbjct: 9360 SKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECRI 9419 Query: 1041 -NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 S +V W RDGE +K ++ + L I + GEY+C+ + S Sbjct: 9420 AGSSPIEVSWLRDGEPLK-AGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTS 9478 Query: 1096 CTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHI 1152 C A++T+ E PP +L Q+V G+ E +T + V W KD +I+ + Sbjct: 9479 CRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNY 9538 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE---PSINFTLRLPEF 1205 ++ L I D D G+Y C +VG C++ +TV+E P + FT + E Sbjct: 9539 NISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVTVKERKNPPV-FTKKPSEH 9597 Query: 1206 ILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 + + + + + V+WYK+ + I ++K+ + L I+ D Sbjct: 9598 MEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHVTDSG 9657 Query: 1265 EYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 YTC + A T + + + PP + + G ++L + Sbjct: 9658 RYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAPLIIQ 9717 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W+ + K + +TK S +A L I DAG Y + N+ G + V + K Sbjct: 9718 WMKDRKELTSGGNTKISFTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVAVRQK 9777 Query: 1381 P 1381 P Sbjct: 9778 P 9778 Score = 184 bits (448), Expect = 2e-44 Identities = 243/1164 (20%), Positives = 451/1164 (38%), Gaps = 87/1164 (7%) Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 VA L ++ +D G +TC A+N AG S +T L ++ L + + Sbjct: 8674 VAVLELQSAGFDDDGVYTCEAQNDAGSVSCSTTLSIKGQLLIDFLWLILIILGLDSEAAV 8733 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 PP+F+K P+ +G D+ L C L + W + ++ + Sbjct: 8734 E-------PPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLS 8786 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E L I ++ G Y N G + ++K++ EPP ++ L +M Sbjct: 8787 EGSS----VTLHIIGLESTDIGQYECKVSNSVGSDTCQTLVKLR----EPPSFVKKLSNM 8838 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI------LKPKKV- 797 V G+ V L A V G+ T++W ++ + DGD IT LK K Sbjct: 8839 TVVLGQEVTLQATVKGSEPITVSWVQDKDHILR-----DGDNRRITFENNTVTLKVFKAD 8893 Query: 798 -KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 G YT N G +E A + V EP + +++ ++V L +V Sbjct: 8894 ASTAGRYTCHLTNDAGTSECFANLNVLEPAK-------IVDKPDALSVTAGDIAALEVKV 8946 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P W+++ ++ +F L + + + ++DSG+Y N GK Sbjct: 8947 CGTPELVTKWFKDGIELASGNKYKISFSRMISCLNVLSTE-KLDSGEYTFEIMNEVGKDL 9005 Query: 917 HGARVTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMD 971 +T+ ++K+ +F + L K T GK +EC+ S + + W+H+ +EI Sbjct: 9006 SKINLTV-LDKIIPPSFSRKL-KDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGP 9063 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE 1027 + EI D G+ KC ++ ET+ + VKE P F+ Q E Sbjct: 9064 NYEISFSNNSCILRVPTLKLSDSGLYKCKAVNEAGTSETAATMDVKEP-PSFVVPPQSLE 9122 Query: 1028 -VKEKDVAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEG 1085 + +V + S + W R + ++P + + + L + N G Sbjct: 9123 ALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVM-LELFNVDRSHAG 9181 Query: 1086 EYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWF 1140 EY+C I+ D ES +++ E P +L++ V KG T E T + V W+ Sbjct: 9182 EYTCQIINDAGKESWPVNLSIKE-PAAFSKKLKDVSVEKGKPLTLECTYTGTPKITVNWY 9240 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCD-LDDAGEYSCEVGNSK----CTAILTVEEPS 1195 KDG ++ S +T L+ D + AG+Y CEV N C A +++ EP Sbjct: 9241 KDGQQVFASYKYNITTTESSCILECLSTDDKEAAGKYLCEVSNDAGRDTCEAAVSILEPP 9300 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 + + E + V A L ++ + V+W+K + + L L Sbjct: 9301 --YFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEYTKGVACLK 9358 Query: 1255 IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 + K T+ D EY+C + S+ +L V + PP + G + Sbjct: 9359 LSKATKADIGEYSCKAENRIGATSSSCRLNVLEAKTPPTFPKKITSLQQTEGQPIRFECR 9418 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 W+ + + +K D +A L I++ E +G Y N+ G Sbjct: 9419 IAGSSPIEVSWLRDGEPLKAGGEFSMLYDDNTAVLQIERGEMRHSGEYTCVATNSVGSTS 9478 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWI 1428 +T+ + PP L ++ + E TG++ I + + ++++I + Sbjct: 9479 CRAKLTLQEPRYPPVFDRKLAPQEVTMGDSIELECHMTGSAPIKVTWSKDHKDIRSGGNY 9538 Query: 1429 SVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEK 1486 ++ + T +I + ++ +A+N+V +S +S+ T +KE K +K Sbjct: 9539 NISCVDNTPHLTILKADKGDTGKYFCHAMNDVGKVSCSSDVT-----VKERKNPPVFTKK 9593 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXX 1542 P +++ +++ G V+WY++ ++ ++ + N Sbjct: 9594 PSEHMEDTEGRLVKIEGRVSGSQPMSVSWYKEDAEIHSSDKYDISFKSNVAVLCIKSSHV 9653 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPP 1601 Y C A N+ G VGI + + + +K G++ + + G P Sbjct: 9654 TDSGRYTCQASNEAGRASCCTTVGISEAKKPPVFDVPLKPLTVDEGEKMSLKCHVCGSAP 9713 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 + W K+ +L + I+ + T+ + I R + Y +A+N AG+ + + Sbjct: 9714 LIIQWMKDRKELTSGGNTKISFTDGTACLEISPASRKDAGDYLCKATNDAGSEFSKAKVA 9773 Query: 1662 VYDKP----SKPEGPVIMREISRE 1681 V KP + E P + + R+ Sbjct: 9774 VRQKPGAALAPAEAPAVAAPVKRQ 9797 Score = 183 bits (446), Expect = 4e-44 Identities = 237/1068 (22%), Positives = 425/1068 (39%), Gaps = 86/1068 (8%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 EG+ +LE ++ A + W +++ P + I + L + +G Sbjct: 2212 EGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQR----LVFSRTHASDQG 2267 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 Y +V + +L + E +++ ++ + + + V +V +P Sbjct: 2268 QYKLVVGKVDTSCTLTV---------EKVHIVKHMEDRVCSESQKVTFRVEV-SHPGIDP 2317 Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W N KP +S HS+TIL K +EG Y A G +SA++TV Sbjct: 2318 VWTVRNQLLKPGAKYKMESKDKVHSLTILDTMK-DEEGQYMFHA----GEQTSSAMLTVS 2372 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 PL Q++TV E T L V N W + + + SE + Sbjct: 2373 GGAITR---PL-----QDVTVAESQTAVLECEVA-NAEAEGRWMKEGQPVDFSENVVSEV 2423 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 G L IT + D G+Y +NS K++ RV E V K L+ TE Sbjct: 2424 KGAVRRLTIT-ITRPQDVGEYSYQVANS--KTTANLRV----EAVKIKKTLRNQTVTETQ 2476 Query: 944 KTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 V LE + ++W N E+ D EI +G D V + Sbjct: 2477 DAVFTLELTHADVKGSQWIKNGVELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLG 2536 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN- 1061 + L V ETI + I+K +D A E+ ++ + V W G +KP Sbjct: 2537 KLSANARLNV-ETI-KIIKKTKDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRC 2594 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 K E+R H KL ++N + + GEY+ ++ C+A +TV L +I+ +++ V + Sbjct: 2595 KILRERRAH--KLILQNVNSSNAGEYTAVVGHLQCSATLTVEAL--QIVKPMKDASVAET 2650 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 ATFE E++ + W KDG EI+ S ++ + GK +LKI + DD+ EY+ G Sbjct: 2651 QAATFECEVSHFNVPSTWLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFICG 2710 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 N + +A LTV I T L + +T + V + E + W K ++ +++ Sbjct: 2711 NDRVSATLTVSPVLI--TSMLKDLNAQERDTITF-EVTVNHEGITYKWLKNGVEVKSSDR 2767 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDYEREYRI 1299 + S TL IR D EY V A ++ L VE V+EF KI D + + Sbjct: 2768 CQVRSRQLTHTLTIRNVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKIIEKK 2827 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIY 1358 K + + + P W+ + + + + + K L I+ V +DAG Y Sbjct: 2828 KAIFECEV-----SEPNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEY 2882 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + ++ A + + + + +PP + +I ++ I ++ E+ + E Sbjct: 2883 SVVAGSSVSKAQLVVEGRDI-RIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNGAE 2941 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + ++ ++ + + S Y F A N ++ E ++++ + Sbjct: 2942 LSLEERFSYVVIRKVHRITISETFRSDAGEYTFIA-GKNRSSVNLRVNIPEPPQILRHME 3000 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY---ENRXX 1534 QS V K L + E + GVPQP+V+WY++ + L K + N+ Sbjct: 3001 PQSVEVGK-LARFSVEVS----------GVPQPQVSWYKNSQMLSAGFKCKFLCEANQHS 3049 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y C A ND+G ++ + ++ V++ + T+ Sbjct: 3050 LLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISSTS 3109 Query: 1595 VIEGIP----------PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 EG P ++ W+ +++ + + ++ E + + I + +Y+ Sbjct: 3110 AREGEPARFHCRVHGDDVKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEGEYS 3169 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPL 1691 A+N+ GT+S TL + D + PE G + + S+T K P+ Sbjct: 3170 CVATNSGGTASCSATLTL-DGQTLPEAGAAVPQWHVSTSLTSIKKAPI 3216 Score = 183 bits (445), Expect = 5e-44 Identities = 233/1035 (22%), Positives = 424/1035 (40%), Gaps = 95/1035 (9%) Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 +W F +E+ P ++ H L + +V+K +G YT V + ASL + L Sbjct: 2052 SWFFGDKELSPSSKHIMSSRRGRH----TLSVKDVRKEDQGKYTFVCGDLRTSASLKMKL 2107 Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785 + P ++ PL + V +G+ L + TW K+ + + + SD Sbjct: 2108 R-------PVTLMLPLTDLSVCEGDIAQLEVR-FSQENVEGTWMKSGQAI----SPSD-R 2154 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 H + + K+ E V T A + + + T + + + + + ++++ Sbjct: 2155 VHIVIDKQVHKLLLENVSTEDAASYSFVVPAQDISTAGKLSVQTID---IVVPLKDLSTV 2211 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 E L A+++ + S+ WY N++ ++PS+ I G LV + + D G YK Sbjct: 2212 EGTKAVLEAKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLVFSRTHAS-DQGQYK 2270 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNK 964 V GK T+ VEKV VKH++ +E K V + SH + W Sbjct: 2271 LV----VGKVD--TSCTLTVEKVHIVKHMEDRVCSESQK-VTFRVEVSHPGIDPVWTVRN 2323 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 + + ++ + + + G +Q +S ML V R LQ Sbjct: 2324 QLLKPGAKYKMESKDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTVSG--GAITRPLQ 2381 Query: 1025 DFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 D V E A+LE E+ + A+ W ++G+ + +N E +G +R+L I T D Sbjct: 2382 DVTVAESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVS-EVKGAVRRLTITITRPQDV 2440 Query: 1085 GEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDG 1143 GEYS + + TA + V + +I L+NQ V + A F +ELT D +W K+G Sbjct: 2441 GEYSYQVANSKTTANLRVEAV--KIKKTLRNQTVTETQDAVFTLELTHADVKGSQWIKNG 2498 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203 E+Q S+ +++ DG Q LKI +C+ D YS ++G A L VE I ++ Sbjct: 2499 VELQSSDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVETIKI---IKKT 2555 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + + + A + + + + V W K + ++ +++ ++ + + LI++ + Sbjct: 2556 KDVTTLMDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQNVNSSNA 2615 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 EYT V+ + + L VE ++ IV ++ + T + F P+ W+ Sbjct: 2616 GEYTAVVGHLQCSATLTVEALQ----IVKPMKDASVAETQAATFECEVSHFNVPS-TWLK 2670 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + I+ + + + K L I D+ Y CG+ V +T+ SP Sbjct: 2671 DGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTF----ICGNDRVSATLTV----SP 2722 Query: 1384 PGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQ 1441 ++L ++++ + E ++ E+ +++ V++ T T +I+ Sbjct: 2723 VLITSMLKDLNAQERDTITFEVTVNHEGITYKWLKNGVEVKSSDRCQVRSRQLTHTLTIR 2782 Query: 1442 NLK--TNSSYRFRA-YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 N+ Y+F A A ++ + E+ + IK+ KI +EK E +E Sbjct: 2783 NVHFGDGGEYQFVAGSAATSANLFVEARVIEFTRKIKDIKI----IEKKKAIFECEVSE- 2837 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 P +V W +DG++L ++ Y + + +D GE Sbjct: 2838 ----------PNIQVMWMKDGQELDLSEERY------VTTAEKYVHRLMIQTVRMSDAGE 2881 Query: 1559 VETSCVVGIQ-QKPVITISNEDIKQKHKVGDEWLV----TAVIE---GIPPPEVIWYKNG 1610 S V G K + + DI+ + V A IE E W KNG Sbjct: 2882 Y--SVVAGSSVSKAQLVVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDDVEGRWLKNG 2939 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 +L ++ ++ K I I E RS + +YT AG + V L+V + PE Sbjct: 2940 AELSLEERFSYVVIRKVHRITISETFRSDAGEYTF----IAGKNRSSVNLRV----NIPE 2991 Query: 1671 GPVIMREISRESVTI 1685 P I+R + +SV + Sbjct: 2992 PPQILRHMEPQSVEV 3006 Score = 171 bits (416), Expect = 2e-40 Identities = 232/1075 (21%), Positives = 420/1075 (39%), Gaps = 116/1075 (10%) Query: 633 PPTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F++ P V G + + EC++ PE D+ W +G EI P E ++ + + Sbjct: 8149 PPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSFLNSL--- 8205 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L++ + G Y A N G S + LK+K E P +I+ L + + + Sbjct: 8206 -ASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVK----EIPTIIKDLAPAELVKDST 8260 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK--VKDEGVYTLKAEN 809 L QV G +TW ++ K +K+ S + L+ K D G Y N Sbjct: 8261 AHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQINGTLGLEVHKCGAADVGEYQCTVAN 8320 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYR 868 G + A + ++EP P F + + TV K + V +P S+ W + Sbjct: 8321 EVGSCTSKATLKLKEP-------PTFTKKLENTDTVLGKMAV-FQCVVEGSPTLSVQWQK 8372 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 ++ I I + F+ N+ ++ + SG Y C N AG++ A T+ V++ Sbjct: 8373 DDNWILEDPKIERTFEN-NVAILKIPACEAVHSGKYSCQVVNEAGQTKCSA--TLTVQEP 8429 Query: 929 TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 + + + G V L+C+ S + KW KE+ + +++ E Sbjct: 8430 PQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENNISSLKI 8489 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D G E I E + K + V ++E Sbjct: 8490 QAAEREDEG------------------EYILEVANHISRTSCKVRLVVLVE--------- 8522 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-V 1103 W++DG+ I K+ ++ + + I D G YSC L + SC + ++ V Sbjct: 8523 --WQKDGKKIFSGV-KHKLIQQDNSVSVEIEQLEPSDAGRYSCKLTNAAGSCESSGSLQV 8579 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 + PP ++ + Q K F+ KG V+WFKD E+ +DG Sbjct: 8580 KEPPSFVSPPEPQSAVPNAKVRFKGTF-KGTPPFTVQWFKDDRELMTGPTCFTGLDGLSC 8638 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA--NTDAYLTVE 1219 L++Y ++ +G YSC+V N+ +A S N T+++ L A + D T E Sbjct: 8639 FLELYSVNISQSGVYSCQVSNAAGSA-----RCSANLTVKVAVLELQSAGFDDDGVYTCE 8693 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 ++ V+ S+ K L+ D LII + LD+++ + Sbjct: 8694 AQNDAGSVSCSTTLSI-----KGQLLIDFLWLILII-------------LGLDSEAAVE- 8734 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 PP +G DV+L + W + K + + + K + Sbjct: 8735 -------PPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSE 8787 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSIN 1398 S +L I +E+TD G Y+ ++ N+ G + V + + PS K N+ + + Sbjct: 8788 GSSVTLHIIGLESTDIGQYECKVSNSVGSDTCQTLVKLREPPSFVKKLSNMTVVLGQEVT 8847 Query: 1399 ICWDEPENTGNSTI-IYYVVEYQEI---DTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + G+ I + +V + I I+ +N T T + +++ R+ + Sbjct: 8848 L---QATVKGSEPITVSWVQDKDHILRDGDNRRITFENNTVT-LKVFKADASTAGRYTCH 8903 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 N+ + SE V++ KI V+KP ++ + L G P+ Sbjct: 8904 LTND---AGTSECFANLNVLEPAKI----VDKP-DALSVTAGDIAALEVKVCGTPELVTK 8955 Query: 1515 WYRDGKKLKTA---KATYENRXX-XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 W++DG +L + K ++ Y N+ G+ + + + K Sbjct: 8956 WFKDGIELASGNKYKISFSRMISCLNVLSTEKLDSGEYTFEIMNEVGKDLSKINLTVLDK 9015 Query: 1571 PVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 + + +K H V G + + G PP + W+ +G ++++ Y I+ + + Sbjct: 9016 IIPPSFSRKLKDCHTVVGKAGEMECKVSGSPPFAISWHHDGEEIQSGPNYEISFSNNSCI 9075 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 +R+ LK S S Y +A N AGTS T+ V + PS P + + +VT Sbjct: 9076 LRVPTLKLSDSGLYKCKAVNEAGTSETAATMDVKEPPSFVVPPQSLEALPGSNVT 9130 Score = 167 bits (405), Expect = 4e-39 Identities = 211/1029 (20%), Positives = 409/1029 (39%), Gaps = 78/1029 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V EG LE R + + W+ G+ I P + + + I+ +H L + NV Sbjct: 2121 VCEGDIAQLEVRF-SQENVEGTWMKSGQAISPSDRVHIVIDKQVHK----LLLENVSTED 2175 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 +Y+ V ++ S L ++T + ++ PLK + +G +L A++ Sbjct: 2176 AASYSFVVPAQD--ISTAGKLSVQTID-----IVVPLKDLSTVEGTKAVLEAKISAQDIS 2228 Query: 765 TITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 ++ W N+K P + T + G + + D+G Y L G +TS +T Sbjct: 2229 SVKWYHNDKQVTPSDRIQTVAKGAKQRL-VFSRTHASDQGQYKLVV----GKVDTSCTLT 2283 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 VE+ + ++ E + V+ + + W N+++ P Sbjct: 2284 VEKVH--------IVKHMEDRVCSESQKVTFRVEVSHPGIDPV-WTVRNQLLKPGAKYKM 2334 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + L I + + + G Y AG+ + A +T+ +T + LQ Sbjct: 2335 ESKDKVHSLTILDTMKD-EEGQYMF----HAGEQTSSAMLTVSGGAIT--RPLQ-DVTVA 2386 Query: 942 EGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 E +T +LEC+ ++ + +W + + ++ +G DVG Sbjct: 2387 ESQTAVLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLTITITRPQDVGEYSYQ 2446 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPK 1059 V + +T+ L V+ + + L++ V E A+ +E+ +++ W ++G ++ Sbjct: 2447 VANSKTTANLRVEAV--KIKKTLRNQTVTETQDAVFTLELTHADVKGSQWIKNGVELQ-S 2503 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 +KY+ G ++ L IRN + DE YS L S A + V + +II + ++ Sbjct: 2504 SDKYEISSDGMVQSLKIRNCNTQDESVYSFKLGKLSANARLNVETI--KIIKKTKDVTTL 2561 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 A+FE+ L+ D V+W G+E++ S+ ++ + + KL + + + +AGEY+ Sbjct: 2562 MDGTASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQNVNSSNAGEYTAV 2621 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 VG+ +C+A LTVE I ++ + V A E+ + TW K IE + Sbjct: 2622 VGHLQCSATLTVEALQI---VKPMKDASVAETQAATFECEVSHFNVPSTWLKDGVEIEMS 2678 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299 EKF ++ K L I ++DD EYT + + + + L V V + D + R Sbjct: 2679 EKFRIVVQGKLHQLKIVNTSKDDSAEYTFICGNDRVSATLTVSPVLITSMLKDLNAQERD 2738 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 +VT V+++ +W+ N +K + + +LTI+ V D G Y+ Sbjct: 2739 TITFEVT--VNHEGITY---KWLKNGVEVKSSDRCQVRSRQLTHTLTIRNVHFGDGGEYQ 2793 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + A++ + +++ I+E + EP + + ++ + Sbjct: 2794 FVAGSAATSANLFVEARVIEFTRKIKDIKIIEKKKAIFECEVSEP-----NIQVMWMKDG 2848 Query: 1420 QEIDTTE--WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 QE+D +E +++ + IQ ++ + + + A + V + ++ Sbjct: 2849 QELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSSVSKAQLVVEGRDIRIAPPA 2908 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533 + +EK I E NED + W ++G +L + + Sbjct: 2909 ERDITVLEKHRATIEFEVNED-----------DVEGRWLKNGAELSLEERFSYVVIRKVH 2957 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y IA + V V I + P I E Q +VG + Sbjct: 2958 RITISETFRSDAGEYTFIAGKNRSSVNLR--VNIPEPPQILRHME--PQSVEVGKLARFS 3013 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 + G+P P+V WYKN L + + + + E+ ++ Y+ EA N G Sbjct: 3014 VEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHSLLLIEVFPEDAAVYSCEAKNDYGA 3073 Query: 1654 SSVEVTLKV 1662 +S +L V Sbjct: 3074 ASSTASLNV 3082 Score = 149 bits (360), Expect = 1e-33 Identities = 150/696 (21%), Positives = 289/696 (41%), Gaps = 32/696 (4%) Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 D+ V++ + T +V + P + L+D V E A L I + A V W + Sbjct: 6720 DISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTI-THAAKVNWLFN 6778 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVV-ELPP 1107 G+++KP K +++ + + +GEY C +E+ ++ +TVV +PP Sbjct: 6779 GQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTTTSSRLTVVPRVPP 6838 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 ++ ++N G+ A F E++ D RW+K G EI+ S ++ L++ Sbjct: 6839 VFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALELV 6898 Query: 1167 DCDLDDAGEYSCEVGN----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 D+GEYSC+V N C A L V E + PE + + +A + Sbjct: 6899 SPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTLFVGKEAVFQCSLTG 6958 Query: 1223 ET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 + +DV W+K I K+ + SD K +L I+ Q Y C ++ T Sbjct: 6959 SSPMDVVWHKDNLAISSEGKYVMKSDKNKYSLHIQSLELAHQGVYLCKASNSVGTATFST 7018 Query: 1282 E--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 E V++ P + +++ V L W + K + + K S + Sbjct: 7019 ELWVIDKPSFVKPFDQASAAVN-DPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFE 7077 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 K A + I K + D+G Y N G + E V + + PS + + +++ Sbjct: 7078 DKVAVVEIPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSI--RKELQTVEALKGGP 7135 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 + E E G + + ++ T++ NI +Q S+ L+ + F + V + Sbjct: 7136 AYLEYEIAGTAPFEITWSKNRKPITSD--KKYNII-SQQSLSRLEILT---FESADVGDY 7189 Query: 1460 DISDASETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + ++E + K + + K + P+ K + ++T ++L G V W +D Sbjct: 7190 QMVVSNEVGKVSTKAVAKLK-EPPSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKD 7248 Query: 1519 GKKLK----TAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVI 1573 + L+ + T++N Y C A N+ G+ ++ + +Q+ + Sbjct: 7249 SEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQKSEATLTVQEPARV 7308 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 I G+ + + I G P +V W+K+G ++ + ++ +T K+ T+ ++I Sbjct: 7309 VEPAASISVT--AGESATLESTISGSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKIL 7366 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 ++S S++Y ++ SN G +L V D+ P Sbjct: 7367 SAEKSDSAEYIMQVSNKVGKDECTCSLTVLDRTMPP 7402 Score = 147 bits (357), Expect = 3e-33 Identities = 143/626 (22%), Positives = 253/626 (40%), Gaps = 47/626 (7%) Query: 795 KKVKDEGVYTLK----AENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKE 846 +K KDE ++ +K AE E I +P P P + R Q TV Sbjct: 1762 RKTKDELLHHMKEKEEAERKRMEEEGKVTIPTFKPERVQLSPSMEAPRILERIQSKTVAP 1821 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYK 905 ++ RV P P W++N ++ +E + + +N+ ELVI +V +E DS Sbjct: 1822 MDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCELVIRDVTAE-DSASIM 1880 Query: 906 CVASNSAGK-SSH------------------GARVTID------VEKVTFVKHLQKSYET 940 A+N AG+ SSH G+ V++ V+F +HL+ + Sbjct: 1881 VKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAKAAVSFTQHLEDATAN 1940 Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 E+ V EC+TS + KW N EI D + + + D C Sbjct: 1941 EKDTMVTFECETSEPFIKVKWLKNNTEIFSGDKYRMHSDRKVHFLSVLIIDLRDDAEYTC 2000 Query: 1000 IVKDQE---TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 ++ D E TS L V+ E I+ +++ EV E EVE++ E + W + + Sbjct: 2001 VLADDESVRTSARLTVEGAALELIKHMENIEVPETYAGEFEVELSREDVEGSWFFGDKEL 2060 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 P +RG L +++ D+G+Y+ + D +A + + P ++ L + Sbjct: 2061 SPSSKHIMSSRRGR-HTLSVKDVRKEDQGKYTFVCGDLRTSASLKMKLRPVTLMLPLTDL 2119 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V +G+ A E+ ++ + W K G I S+ + + ID + KL + + +DA Y Sbjct: 2120 SVCEGDIAQLEVRFSQENVEGTWMKSGQAISPSDRVHIVIDKQVHKLLLENVSTEDAASY 2179 Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSV 1235 S V + + +I+ + L + V T A L +I + + V WY Sbjct: 2180 SFVVPAQDISTAGKLSVQTIDIVVPLKDLSTV-EGTKAVLEAKISAQDISSVKWYHNDKQ 2238 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295 + +++ ++ K+ L+ + DQ +Y V+ ++ L VE V IV + Sbjct: 2239 VTPSDRIQTVAKGAKQRLVFSRTHASDQGQYKLVVGKVDTSCTLTVEKVH----IVKHME 2294 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + VT V+ + P + W V ++++K K K SLTI + Sbjct: 2295 DRVCSESQKVTFRVEV-SHPGIDPVWTVRNQLLKPGAKYKMESKDKVHSLTILDTMKDEE 2353 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKP 1381 G Y A + ++ + +P Sbjct: 2354 GQYMFHAGEQTSSAMLTVSGGAITRP 2379 Score = 147 bits (356), Expect = 3e-33 Identities = 181/779 (23%), Positives = 294/779 (37%), Gaps = 46/779 (5%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + E PP F KP+ + G + + +C L D+ W K + E ++SD Sbjct: 6927 VTELYPPVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVW-HKDNLAISSEG-KYVMKSD 6984 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + Y L I +++ +G Y A N G A+ L + + P ++P Sbjct: 6985 KNKYS--LHIQSLELAHQGVYLCKASNSVGTATFSTELWV----IDKPSFVKPFDQASAA 7038 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDTHSITILKPKKVKDEGVYTL 805 + V L QV + TI W ++ K V +++ K S D ++ + K+KD G Y Sbjct: 7039 VNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVC 7098 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A N G + AV+ V+ EPP Q + + G L + IT Sbjct: 7099 TATNEAGSSSCEAVVMVQ-------EPPSIRKELQTVEALKGGPAYLEYEIAGTAPFEIT 7151 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W +N + I+ + L I +S D GDY+ V SN GK S A + Sbjct: 7152 WSKNRKPITSDKKYNIISQQSLSRLEILTFES-ADVGDYQMVVSNEVGKVSTKAVAKLK- 7209 Query: 926 EKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMDHR-EIIQEGRXX 982 E +F K + S G TV L+ + S ++ KW + + + D + + Sbjct: 7210 EPPSFTKRVD-SVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVA 7268 Query: 983 XXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 G C ++ Q++ L V+E + V + A LE Sbjct: 7269 FLSIATVAISHGGKYVCQAENEAGQQKSEATLTVQEP-ARVVEPAASISVTAGESATLES 7327 Query: 1039 EIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY----SCILR 1092 I+ S V W +DG E+ +K K + K+ S D EY S + Sbjct: 7328 TISGSPELKVKWFKDGKEMTSGRKCKMTVKDNTATMKILSAEKS--DSAEYIMQVSNKVG 7385 Query: 1093 DESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149 + CT +TV++ +PP L+ N GN A+ + +++ + + WFKD EI Sbjct: 7386 KDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSGSQPMTIAWFKDDHEITAG 7445 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEF 1205 Q L+I + D+G Y C NS + + L V+EP FT++ Sbjct: 7446 PKFQAGFKDHSATLQIAGLEKADSGVYKCRATNSAGFKETSGTLYVKEPP-TFTVKPDGQ 7504 Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 ++P +T ++ L V W+K+ I + + D +L ++ D Sbjct: 7505 DVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATSSSLELQAVKPSDSAR 7564 Query: 1266 YTC-VLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y C V DA + V+ PP V E + G L P +W Sbjct: 7565 YACQVSNDAGKVDCTALLFVKEPPTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFK 7624 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + I + D ASL I + ++G Y + G VT+ PS Sbjct: 7625 DEMEITPGPKYTMAADDLVASLEIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPS 7683 Score = 146 bits (354), Expect = 6e-33 Identities = 194/988 (19%), Positives = 375/988 (37%), Gaps = 71/988 (7%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSI 789 E P+++E ++S V + V +VVG P P W KN V+ D Sbjct: 1806 EAPRILERIQSKTVAPMDEVRFRVRVVGRPEPECQWFKNGILVEKTERVYWFWPEDNVCE 1865 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT--EENAE--------PPL----- 834 +++ +D +KA N G A + A + V+ +++ P Sbjct: 1866 LVIRDVTAEDSASIMVKANNVAGEASSHAFLLVQGNAMLQDDTRCAGSCVSLPGFLIAAK 1925 Query: 835 ----FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 F ++ T EK T+ T P + W +NN I + + D + L Sbjct: 1926 AAVSFTQHLEDATANEKDTMVTFECETSEPFIKVKWLKNNTEIFSGDKYRMHSDRKVHFL 1985 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 + +D D +Y CV ++ + AR+T++ + +KH++ + E E E Sbjct: 1986 SVLIIDLR-DDAEYTCVLADDESVRT-SARLTVEGAALELIKHME-NIEVPETYAGEFEV 2042 Query: 951 QTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009 + S V W+ KE+S + D G + D TS Sbjct: 2043 ELSREDVEGSWFFGDKELSPSSKHIMSSRRGRHTLSVKDVRKEDQGKYTFVCGDLRTSAS 2102 Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRG 1069 L +K + L D V E D+A LEV + E + W + G+ I P + + Sbjct: 2103 LKMKLRPVTLMLPLTDLSVCEGDIAQLEVRFSQENVEGTWMKSGQAISPSDRVHIVIDK- 2161 Query: 1070 HIRKLYIRNTSVHDEGEYSCIL--RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127 + KL + N S D YS ++ +D S +++V + +I+ L++ +G KA E Sbjct: 2162 QVHKLLLENVSTEDAASYSFVVPAQDISTAGKLSVQTI--DIVVPLKDLSTVEGTKAVLE 2219 Query: 1128 IELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 +++ D + V+W+ + ++ S+ IQ G KQ+L D G+Y VG + Sbjct: 2220 AKISAQDISSVKWYHNDKQVTPSDRIQTVAKGAKQRLVFSRTHASDQGQYKLVVGKVDTS 2279 Query: 1187 AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLIS 1246 LTVE+ I ++ E + + VE+ +D W + +++ K+ + S Sbjct: 2280 CTLTVEKVHI---VKHMEDRVCSESQKVTFRVEVSHPGIDPVWTVRNQLLKPGAKYKMES 2336 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 K +L I +D++ +Y + S+ L V + D S Sbjct: 2337 KDKVHSLTILDTMKDEEGQYMFHAGEQTSSAMLTVSGGAITRPLQDV-----TVAESQTA 2391 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 +L A + W+ + + ++ + LTI D G Y ++ N+ Sbjct: 2392 VLECEVANAEAEGRWMKEGQPVDFSENVVSEVKGAVRRLTITITRPQDVGEYSYQVANSK 2451 Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426 A++ + + K + E + + + G S I VE Q D E Sbjct: 2452 TTANLRVEAVKIKKTL--RNQTVTETQDAVFTLELTHADVKG-SQWIKNGVELQSSDKYE 2508 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 S + + N + S Y F+ ++ ++A E K+IK+TK + ++ Sbjct: 2509 ISSDGMVQSLKIRNCNTQDESVYSFKLGKLS----ANARLNVETIKIIKKTKDVTTLMDG 2564 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546 + ++D+ + +F G + ++ + K +N Sbjct: 2565 TASFEMSLSHDDVPVKWMFKGAELKPSDRCKILRERRAHKLILQN--------VNSSNAG 2616 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y + G ++ S + ++ ++ + + + + E V+ +P Sbjct: 2617 EYTAVV----GHLQCSATLTVEALQIVKPMKDASVAETQAATFECEVSHF--NVPS---T 2667 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN-----TAGTSSVEVTL 1660 W K+G ++E +++ I + K ++I + S++YT N T S V +T Sbjct: 2668 WLKDGVEIEMSEKFRIVVQGKLHQLKIVNTSKDDSAEYTFICGNDRVSATLTVSPVLITS 2727 Query: 1661 KVYDKPSKPEGPVIMR-EISRESVTIEW 1687 + D ++ + ++ E +T +W Sbjct: 2728 MLKDLNAQERDTITFEVTVNHEGITYKW 2755 Score = 112 bits (269), Expect = 1e-22 Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 25/248 (10%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568 P F++ +R G+ +F V G P+P+++WF I+P+ + ++++ N ATL Sbjct: 3220 PTFIQPIRSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATL 3279 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV-----------------------EAPLS 605 +I + F E AG +TC A N+AG A+ + L + + P Sbjct: 3280 IIVDAFTEHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVKEQTQIQIQQDIKEPFH 3339 Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665 GSE V + + P+F+KK K Q V EG + L+C LVA P P I Sbjct: 3340 GSGSEELVRRDPTDGCSSTTSGT-GNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSI 3398 Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W + + + +S MHM+ + L I VK+ G+Y V+A+N EG A L Sbjct: 3399 LWFHNNKTLGKARRRRICSDSQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASL 3458 Query: 726 KIKTGEKE 733 + E++ Sbjct: 3459 LVSMREEQ 3466 Score = 110 bits (265), Expect = 4e-22 Identities = 154/710 (21%), Positives = 280/710 (39%), Gaps = 47/710 (6%) Query: 1079 TSVHDEGEYSC-ILRD--ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATFEIELTKG 1133 T++H+E ++R+ E E TVV P ++T L++ V++ +KAT +T Sbjct: 6711 TTIHEEETVDISVVREHREVLVEETTVVRRREHPTVVTALEDISVDEDSKATLSTTITHA 6770 Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEV----GNSKCTAI 1188 A V W +G ++ + + + L I + GEY CE G + ++ Sbjct: 6771 -AKVNWLFNGQLVKPGKEFRCSKEKDTYTLVISKVVKEMHQGEYVCEAENEAGKTTTSSR 6829 Query: 1189 LTVEEPSINFTLRLPEFIL-VPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLIS 1246 LTV P + RL L + + A E+ D ++ WYK I+ +EK+ ++S Sbjct: 6830 LTVV-PRVPPVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVS 6888 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVE-FPPKIVDYEREYRIKRGS 1303 L + + D EY+C + + T + V E +PP V + G Sbjct: 6889 SSTSSALELVSPVKADSGEYSCKVSNPHGVDTCAASLIVTELYPPVFVSKPEPMTLFVGK 6948 Query: 1304 DVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 + + W N I + K+ S D SL I+ +E G+Y + Sbjct: 6949 EAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVMKS-DKNKYSLHIQSLELAHQGVYLCKA 7007 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQ 1420 N+ G A + ++DKPS KP + S+++N + + N I + + + Sbjct: 7008 SNSVGTATFSTELWVIDKPSFV-KP--FDQASAAVNDPVRLECQVNEDTGVTIIWTRDGK 7064 Query: 1421 EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 ++ + + K I K S ++ A NE S + E +++E Sbjct: 7065 KVHQSMDCKLSFEDKVAVVEIPKAKLKDSGKYVCTATNEA----GSSSCEAVVMVQEP-- 7118 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXX 1535 P++ K L+ + L G ++TW ++ K + + K + ++ Sbjct: 7119 --PSIRKELQTVEALKGGPAYLEYEIAGTAPFEITWSKNRKPITSDKKYNIISQQSLSRL 7176 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y+ + N+ G+V T V +++ P T + + +G + Sbjct: 7177 EILTFESADVGDYQMVVSNEVGKVSTKAVAKLKEPPSFTKRVDSVTAV--LGTTVKLQGT 7234 Query: 1596 IEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 ++G P V W K+ L ++D +T + + I + SH KY +A N AG Sbjct: 7235 VKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLSIATVAISHGGKYVCQAENEAGQQ 7294 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL-TKYAIEKHEPDNNRW 1713 E TL V + E + + ES T+E G EL K+ + E + R Sbjct: 7295 KSEATLTVQEPARVVEPAASISVTAGESATLE---STISGSPELKVKWFKDGKEMTSGRK 7351 Query: 1714 IKVADVDRDVETYCIQ-KLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 K+ D + + +++ EY+ +V N VG E S ++ +T Sbjct: 7352 CKMTVKDNTATMKILSAEKSDSAEYIMQV--SNKVGKDECTCSLTVLDRT 7399 Score = 107 bits (257), Expect = 3e-21 Identities = 132/552 (23%), Positives = 217/552 (39%), Gaps = 43/552 (7%) Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664 S G T A +L PP +KP++ V GS + L P Sbjct: 8028 SKDGGSYTCIAKNKAGAVQCSAILLVKEPPCILEKPESMNVLPGSKVHFNVLLSGTPPLT 8087 Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 I W +EI+ + SV ++ + L + K G Y N G S Sbjct: 8088 IKWFKNQKEILSSADCSVIKDNT----STSLALFFAKSSDSGEYRCEIQNDVGSTSCQAT 8143 Query: 725 LKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783 L + KEPP+ P + + R G++ + QV G P + W K + Sbjct: 8144 LFV----KEPPKFTRTPARVSVTRLGQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQM 8199 Query: 784 GDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 +S+ L+ + KD G+Y +A N G S + V+ E P I Sbjct: 8200 SFLNSLASLEVCGTETKDSGLYYCEARNEAGSESCSMELKVK-------EIPTIIKDLAP 8252 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEID 900 + + T L +VT +TWYR+ EI S ++ +G + L + + D Sbjct: 8253 AELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAKHSFSQING-TLGLEVHKCGA-AD 8310 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVST 958 G+Y+C +N G + A + + E TF K L+ + +T GK + +C + S T+S Sbjct: 8311 VGEYQCTVANEVGSCTSKATLKLK-EPPTFTKKLENT-DTVLGKMAVFQCVVEGSPTLSV 8368 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKE 1014 +W + I E E G C V ++ + S L V+E Sbjct: 8369 QWQKDDNWILEDPKIERTFENNVAILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTVQE 8428 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG-EIIKPKKNKYDFEKRGHIR 1072 P+ K + +V D L+ ++ A V W ++G E+ +++K FE +I Sbjct: 8429 P-PQITEKPEVIKVTVGDPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFE--NNIS 8485 Query: 1073 KLYIRNTSVHDEGEYSCILRDE----SCTAE-VTVVELPPE---IITRLQNQKVNKGNKA 1124 L I+ DEGEY + + SC V +VE + I + ++++ + + N Sbjct: 8486 SLKIQAAEREDEGEYILEVANHISRTSCKVRLVVLVEWQKDGKKIFSGVKHKLIQQDNSV 8545 Query: 1125 TFEIE-LTKGDA 1135 + EIE L DA Sbjct: 8546 SVEIEQLEPSDA 8557 Score = 99.1 bits (236), Expect = 1e-18 Identities = 69/229 (30%), Positives = 110/229 (48%), Gaps = 9/229 (3%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTK--SDGDTHS 788 + P +PL+S++ +G + AQV G+P P ++W ++ + V ALP S D + Sbjct: 4 QAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRA 63 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + L G Y+++A N G A ++A + V T E A PP F+ R Q TV++ Sbjct: 64 VLRLTAVTAAHSGRYSVRATNGAGQATSTAELLV---TVETA-PPNFVQRLQSSTVRQGS 119 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 ++L RVT P P++ +YR I S DG+ L+I E DSG Y A Sbjct: 120 QVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPE-DSGTYSVTA 178 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957 +NS+G+++ A + + E+ K + T E +T Q T S Sbjct: 179 ANSSGRATSTAELLVQGEEAMPTKKTKTVVSTSEIRTSKARVQKIKTTS 227 Score = 98.7 bits (235), Expect = 2e-18 Identities = 115/423 (27%), Positives = 179/423 (42%), Gaps = 71/423 (16%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568 P + + P+ G +F +V G P+PQ++W++ + ++ S F+ + + N +L Sbjct: 2993 PQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQML--SAGFKCKFLCEANQHSL 3050 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 ++ EVFPEDA ++C AKN G ASST L VE SE+ D+ Sbjct: 3051 LLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEV------SEVV------------SPDL 3092 Query: 629 LEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + PP + + EG CR V + I+W K +EI E ++ D Sbjct: 3093 AAAVAPPVITSPISSTSAREGEPARFHCR-VHGDDVKISWFHKEKEIKQSEFFRMSQFED 3151 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI------KTGEKEP------- 734 C L+I+ V EG Y+ VA N G AS L + + G P Sbjct: 3152 S---CQ-LEISRVYPEDEGEYSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTS 3207 Query: 735 ------------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS 782 P I+P++S V G A V G P+P ++W N +P++ PT + Sbjct: 3208 LTSIKKAPIGQKPTFIQPIRSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQ--PTTN 3265 Query: 783 -----DGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAE 831 + T++ T I+ + G YT +A NS G A SA +T+ EE T + Sbjct: 3266 VVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVKEQ 3325 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGEN 887 + I + + G+ +LV R + S T N + PS T F +GE Sbjct: 3326 TQIQIQQDIKEPFHGSGSEELVRRDPTDGCSSTTSGTGN--VKPSFTKKLKFQSVLEGEP 3383 Query: 888 IEL 890 +EL Sbjct: 3384 VEL 3386 Score = 92.7 bits (220), Expect = 1e-16 Identities = 128/582 (21%), Positives = 218/582 (37%), Gaps = 60/582 (10%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 K K V E EC + P WL G EI E + ++ +H LKI Sbjct: 2640 KPMKDASVAETQAATFECEVSHFNVPS-TWLKDGVEIEMSEKFRIVVQGKLHQ----LKI 2694 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 N K YT + N A+L + P + LK + ++ +++ Sbjct: 2695 VNTSKDDSAEYTFICGNDRVSATLTV---------SPVLITSMLKDLNAQERDTITFEV- 2744 Query: 758 VVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V + T W KN VK+ +S TH++TI + D G Y A G A Sbjct: 2745 TVNHEGITYKWLKNGVEVKSSDRCQVRSRQLTHTLTI-RNVHFGDGGEYQFVA----GSA 2799 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 TSA + VE E F + ++I + EK V+ P + W ++ + + Sbjct: 2800 ATSANLFVEARVIE------FTRKIKDIKIIEKKKAIFECEVSE-PNIQVMWMKDGQELD 2852 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 SE + + ++ D+G+Y VA +S K A++ ++ + Sbjct: 2853 LSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSSVSK----AQLVVEGRDIRIAPPA 2908 Query: 935 QKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 ++ E +E + + V +W N E+S + + + D Sbjct: 2909 ERDITVLEKHRATIEFEVNEDDVEGRWLKNGAELSLEERFSYVVIRKVHRITISETFRSD 2968 Query: 994 VGVIKCIVKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWER 1051 G I +S L V P+ +R ++ V+ +A VE++ V W + Sbjct: 2969 AGEYTFIAGKNRSSVNLRVNIPEPPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYK 3028 Query: 1052 DGEIIKPK-KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV---- 1102 + +++ K K+ E H L + D YSC +++ S TA + V Sbjct: 3029 NSQMLSAGFKCKFLCEANQH--SLLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSE 3086 Query: 1103 --------VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 PP I + + + +G A F + D + WF EI+ S ++ Sbjct: 3087 VVSPDLAAAVAPPVITSPISSTSAREGEPARFHCRVHGDDVKISWFHKEKEIKQSEFFRM 3146 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVE 1192 + +L+I +D GEYSC NS C+A LT++ Sbjct: 3147 SQFEDSCQLEISRVYPEDEGEYSCVATNSGGTASCSATLTLD 3188 Score = 88.2 bits (209), Expect = 2e-15 Identities = 114/490 (23%), Positives = 190/490 (38%), Gaps = 43/490 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E M P F+ + TP+G+T+ FEC + G P P ++WF+ I P+ ++ + Sbjct: 5365 EVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEG 5424 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS----DHGSEMTVXXXXXX 619 + L I V +D+G + C A N G S L+V + G E+T Sbjct: 5425 DNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVNAKAFAGRTRGREVTAVSLRSA 5484 Query: 620 XXXXXXADILEGIPPTFSKKP-----KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 D++ G ++ + ++ E + RLVA + +GE+ Sbjct: 5485 KIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADESQRAVRLVANADRQSETSEQGEKY 5544 Query: 675 VPDENISVAIESDMHMYCSVL-KITNVKKFQ------EGTYTVVAVNREGEASLPIVLK- 726 V N V E K +++ FQ + + N A P++L+ Sbjct: 5545 V-SINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTESPPKFIIPLTNITAAAGTPVILQC 5603 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN-----PRPTITWCKNNKPVKALPT- 780 + +G P E K I+ + VG+ P + W N K + + Sbjct: 5604 LVSGTPNP--TAEWYKDGGRVTDSRCIIQEKTVGHFNLLITNPVVQWSHNGKVITSSSVY 5661 Query: 781 KSDGDTHSITILKPKKVKD-EGVYTLKAENSEG------IAETSAVIT------VEEPTE 827 K + T++ K + EG Y+ A N G E AV VE+ + Sbjct: 5662 KLIEEREDYTLVITKVTSEYEGEYSCTATNRFGQTTCTTYLEVKAVDVSQAEKWVEKMFK 5721 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDG 885 +PP F Q E + +V+ +PVP + WY+ + P I N DG Sbjct: 5722 VTGQPPKFSVPIQPSRCPEGTEVFFHYQVSGDPVPDVKWYKGAFQVQPGRNCVIISNPDG 5781 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 L + ++ E DSG Y C ASN+ G++S A + + E V K Q + ++G Sbjct: 5782 SGC-LSLKSLKQE-DSGMYMCRASNTFGEASSSAELAVFKESVVVSKQEQLTVVQKKGYK 5839 Query: 946 VILECQTSHT 955 V + Q + + Sbjct: 5840 VSVTEQATES 5849 Score = 84.6 bits (200), Expect = 3e-14 Identities = 59/194 (30%), Positives = 97/194 (50%), Gaps = 9/194 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 PTF++ ++ EGS E ++ P P+++W G+ + V I SD Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGR--- 62 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +VL++T V G Y+V A N G+A+ L + T E PP ++ L+S VRQG V Sbjct: 63 AVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLV-TVETAPPNFVQRLQSSTVRQGSQV 121 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L +V G P PT+ + + +++ DGD +S+ I + +D G Y++ A N Sbjct: 122 RLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFP-EDSGTYSVTAAN 180 Query: 810 SEGIAETSAVITVE 823 S G A ++A + V+ Sbjct: 181 SSGRATSTAELLVQ 194 Score = 81.4 bits (192), Expect = 2e-13 Identities = 81/337 (24%), Positives = 132/337 (39%), Gaps = 42/337 (12%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + + Q V+ G + +P+P ++W + + E++ H Sbjct: 2992 PPQILRHMEPQSVEVGKLARFSVEVSGVPQPQVSWYKNSQMLSAGFKCKFLCEANQHS-- 3049 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---------EPPQVIEPLKS 743 L + V Y+ A N G AS L ++ E PP + P+ S Sbjct: 3050 --LLLIEVFPEDAAVYSCEAKNDYGAASSTASLNVEVSEVVSPDLAAAVAPPVITSPISS 3107 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEG 801 R+GE +V G+ I+W K +K L+ +V +DEG Sbjct: 3108 TSAREGEPARFHCRVHGDD-VKISWFHKEKEIKQSEFFRMSQFEDSCQLEISRVYPEDEG 3166 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENA----------------------EPPLFINRF 839 Y+ A NS G A SA +T++ T A + P FI Sbjct: 3167 EYSCVATNSGGTASCSATLTLDGQTLPEAGAAVPQWHVSTSLTSIKKAPIGQKPTFIQPI 3226 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 + TV + A V+ P P ++W+ N I P+ + +F+ + VD+ Sbjct: 3227 RSCTVAHGAVARFHACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFT 3286 Query: 900 D-SGDYKCVASNSAGKSSHGARVTI---DVEKVTFVK 932 + +G Y C A+NSAG+++ A +TI E+VT VK Sbjct: 3287 EHAGQYTCRAANSAGEAACSATLTITKVQQEEVTVVK 3323 Score = 79.8 bits (188), Expect = 8e-13 Identities = 39/99 (39%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 ++E ++ P + L+ +G ++ ECQ+ G P P I WFR+ I+ S DF Y Sbjct: 585 AQEPAVPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSY-T 643 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 D +A LVIRE F ED+G F+C A N AG S++ L+V+ Sbjct: 644 DGIARLVIREAFAEDSGRFSCTATNEAGTISTSCYLLVK 682 Score = 79.4 bits (187), Expect = 1e-12 Identities = 38/96 (39%), Positives = 63/96 (65%), Gaps = 1/96 (1%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++ P FV++L+ GS V+ + +V G P P + ++R+ A I+ S DFQ+ D D + Sbjct: 100 ETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGD-L 158 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +L+I E FPED+GT++ A N++G A+ST EL+V+ Sbjct: 159 YSLLIAEAFPEDSGTYSVTAANSSGRATSTAELLVQ 194 Score = 73.3 bits (172), Expect = 7e-11 Identities = 77/321 (23%), Positives = 134/321 (41%), Gaps = 33/321 (10%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q + P F++ L K + ++ F +V G P P++ WF + +M D D++ Sbjct: 5170 QGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSI 5229 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 +L + +V D G + C A N G A S T ++V LS + Sbjct: 5230 -SLTVLDVTKADQGEYICEAVNNVGEARSVTLVVV---LSQE-MRLMPPPPAVTHQHVME 5284 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 D+ + S+ P Q +ILLE V + E ++ K +I+ I Sbjct: 5285 FDVEDN---DTSRSPSPQ------EILLE---VELDENEVKEFEKQVKII---TIPEYTA 5329 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + M S+ + +V ++EG V + L I ++ + PP+ I P+ M Sbjct: 5330 DNKSMIVSLDVLPSV--YEEGAVDFVTHEHD---DLKIAFEV---TEMPPRFINPICDME 5381 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEG 801 +G +++ ++G P P ++W K +K + K S+GD H + I +D G Sbjct: 5382 TPEGTTILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKIC-TVTTQDSG 5440 Query: 802 VYTLKAENSEGIAETSAVITV 822 VY +A N G + A + V Sbjct: 5441 VYICRAINVVGETLSRASLVV 5461 Score = 72.5 bits (170), Expect = 1e-10 Identities = 72/328 (21%), Positives = 133/328 (40%), Gaps = 22/328 (6%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD- 561 S ++ AP F++K + +G +V FECQV G P+P + W + + +++ Y Sbjct: 733 SAGETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKR 792 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXX 618 + L I F +DAG + KN G S++ L+ E L G Sbjct: 793 ETGECKLEISMTFADDAGEYAIFVKNPHGEVSASASLLEEGTGTVLLSSGCHRPWLRGQG 852 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 + E + K+ + E + +++ V + + + + +V + Sbjct: 853 STSASVFTEQYE----AYMKQHDLTFKTEVTTTVIQEPAVIVTQMEQKQITTPVSVVSER 908 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 ++ + + L+I + ++E +V +RE +++ GE E P Sbjct: 909 EFLISAFEERIIQEIELRIMRI-TYRE----LVTEDRE------LMVTAAEGEAEQPAFN 957 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPK 795 P+K+ + +G V ++ G P P I W K+ +P ++ D + L Sbjct: 958 TPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQV 1017 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVE 823 +DEGVYT A N G A +S + VE Sbjct: 1018 LPEDEGVYTAFAANVLGNAVSSGKLYVE 1045 Score = 71.7 bits (168), Expect = 2e-10 Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 43/313 (13%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P ++ L P ST ECQV G ++TW+R IK S + + L Sbjct: 8244 PTIIKDLAPAELVKDSTAHLECQVTGTSPFEVTWYRDAKEIKSSAK-HSFSQINGTLGLE 8302 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + + D G + C N G +S L ++ P L Sbjct: 8303 VHKCGAADVGEYQCTVANEVGSCTSKATLKLKEP-------------------PTFTKKL 8343 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E K Q V EGS P + W I+ D I E+++ Sbjct: 8344 ENTDTVLGKMAVFQCVVEGS-----------PTLSVQWQKDDNWILEDPKIERTFENNV- 8391 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 ++LKI + G Y+ VN G+ L + +EPPQ+ E + + V G Sbjct: 8392 ---AILKIPACEAVHSGKYSCQVVNEAGQTKCSATLTV----QEPPQITEKPEVIKVTVG 8444 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 + V L +V G+P + W K K ++++ ++I+ LK + +DEG Y L+ Sbjct: 8445 DPVSLDCKVTGSPALKVKWMKEGKELQSIRQHKLVFENNISSLKIQAAEREDEGEYILEV 8504 Query: 808 ENSEGIAETSAVI 820 N I+ TS + Sbjct: 8505 ANH--ISRTSCKV 8515 Score = 68.9 bits (161), Expect = 1e-09 Identities = 94/466 (20%), Positives = 186/466 (39%), Gaps = 43/466 (9%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 +PP + L ++V + + TF E+ V+WF + +++ + I++ DG L Sbjct: 5172 VPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDSISL 5231 Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTV---------EEPSI------NFTLRLPE 1204 + D D GEY CE VG ++ ++ V P++ F + + Sbjct: 5232 TVLDVTKADQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDVEDND 5291 Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL-IIRKCTEDDQ 1263 P+ + L VE+ DE +V ++K+ I ++T + +L ++ E+ Sbjct: 5292 TSRSPSPQEILLEVEL-DEN-EVKEFEKQVKIITIPEYTADNKSMIVSLDVLPSVYEEGA 5349 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 ++ + K+ EV E PP+ ++ + G+ + P P W Sbjct: 5350 VDF---VTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGTPSPIVSWFK 5406 Query: 1324 -NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + KI K S + + L I V D+G+Y R N G ++ +++ + Sbjct: 5407 GDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVNAKA 5466 Query: 1383 PPGKPNILEIDSSSINICWDEPEN----TGNSTI-------IYYVVEY-QEIDTTEWI-- 1428 G+ E+ + S+ +P+ G +++ I E+ QE D ++ Sbjct: 5467 FAGRTRGREVTAVSLRSAKIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADESQRAVR 5526 Query: 1429 SVKNITK-TQTSIQNLK-TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 V N + ++TS Q K + ++ A E + ++++ + P Sbjct: 5527 LVANADRQSETSEQGEKYVSINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTESPPKFII 5586 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 PL NIT + L C+ G P P WY+DG ++ ++ + + Sbjct: 5587 PLTNITAAAGTPVILQCLVSGTPNPTAEWYKDGGRVTDSRCIIQEK 5632 Score = 67.3 bits (157), Expect = 4e-09 Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 15/188 (7%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIK----PKKNKYDFEKRGHI 1071 P F + LQ E A E +++ S +V W RDG+++ P + R + Sbjct: 6 PTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRAVL 65 Query: 1072 RKLYIRNTSVHDEGEYSCILRD----ESCTAE--VTVVELPPEIITRLQNQKVNKGNKAT 1125 R + T+ H G YS + + TAE VTV PP + RLQ+ V +G++ Sbjct: 66 RLTAV--TAAHS-GRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVR 122 Query: 1126 FEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 ++ +T V+++++G+EIQ S Q+ DG L I + +D+G YS NS Sbjct: 123 LDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSVTAANSS 182 Query: 1185 CTAILTVE 1192 A T E Sbjct: 183 GRATSTAE 190 Score = 66.1 bits (154), Expect = 1e-08 Identities = 63/297 (21%), Positives = 117/297 (39%), Gaps = 24/297 (8%) Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 E AE+S++ T+EE + PP F+ + V E ++ A V P P + W+ N Sbjct: 5154 ETTAESSSLATLEEKGQ--GVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNK 5211 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + + I DG++I L + +V ++ D G+Y C A N+ G++ V + +++ Sbjct: 5212 TQLVEDDRIKMERDGDSISLTVLDV-TKADQGEYICEAVNNVGEARSVTLVVVLSQEMRL 5270 Query: 931 ------VKHLQ-KSYETEEGKT--------VILECQTSHTVSTKWYHNKKEISGMDHREI 975 V H ++ E+ T ++LE + ++ +K++ + E Sbjct: 5271 MPPPPAVTHQHVMEFDVEDNDTSRSPSPQEILLEVELDENEVKEF---EKQVKIITIPEY 5327 Query: 976 IQEGRXXXXXXXXX-XXXDVGVIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 + + + G + + + + V E P FI + D E E Sbjct: 5328 TADNKSMIVSLDVLPSVYEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTT 5387 Query: 1034 AILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 + E + + +V W + + I P KY G L I + D G Y C Sbjct: 5388 ILFECSLMGTPSPIVSWFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYIC 5444 Score = 64.1 bits (149), Expect = 4e-08 Identities = 31/99 (31%), Positives = 49/99 (49%), Gaps = 1/99 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E P F +K+ +G ++FEC++ G +++W R +K +F M Y DDN Sbjct: 9391 EAKTPPTFPKKITSLQQTEGQPIRFECRIAGSSPIEVSWLRDGEPLKAGGEFSMLY-DDN 9449 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 A L I +G +TCVA N+ G S +L ++ P Sbjct: 9450 TAVLQIERGEMRHSGEYTCVATNSVGSTSCRAKLTLQEP 9488 Score = 60.1 bits (139), Expect = 7e-07 Identities = 55/261 (21%), Positives = 92/261 (35%), Gaps = 3/261 (1%) Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 ++ S L+ + PP + + R+ +T + P P +W N + + Sbjct: 5158 ESSSLATLEEKGQGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVED 5217 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGKPNI 1389 K D S SLT+ V D G Y NN G A V +L + P P + Sbjct: 5218 DRIKMERDGDSISLTVLDVTKADQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAV 5277 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSS 1448 ++ ++ + + I VE E + E+ VK IT + + N S Sbjct: 5278 THQHVMEFDVEDNDTSRSPSPQEILLEVELDENEVKEFEKQVKIITIPEYTADNKSMIVS 5337 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 E + + + K+ E P P+ ++ T I C G Sbjct: 5338 LDVLPSVYEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPICDMETPEGTTILFECSLMGT 5397 Query: 1509 PQPKVTWYRDGKKLKTAKATY 1529 P P V+W++ KK+ Y Sbjct: 5398 PSPIVSWFKGDKKIPPNSKKY 5418 Score = 59.7 bits (138), Expect = 9e-07 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 8/157 (5%) Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGE 886 + + P F Q + E A+V+ +PVP ++W+R+ +++S + + +F Sbjct: 2 STQAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDG 61 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR--VTIDVEKVTFVKHLQKSYETEEGK 944 L +T V + SG Y A+N AG+++ A VT++ FV+ LQ S +G Sbjct: 62 RAVLRLTAV-TAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSS-TVRQGS 119 Query: 945 TVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEG 979 V L+ + + S K+Y EI +I+Q+G Sbjct: 120 QVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDG 156 Score = 59.3 bits (137), Expect = 1e-06 Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 14/230 (6%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQDFQMYYDDDN 564 + AP F + L+ +GS FE QV G P P+++WFR Q + Q+ + D Sbjct: 3 TQAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGR 62 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 A L + V +G ++ A N AG A+ST EL+V + + Sbjct: 63 -AVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQV 121 Query: 625 XADI-LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE---NI 680 D+ + GIP P ++ EG++I + + D+ L E D ++ Sbjct: 122 RLDVRVTGIP-----SPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSV 176 Query: 681 SVAIESDMHMYCSVLKITNVKKF-QEGTYTVVAVNREGEASLPIVLKIKT 729 + A S + L + + + T TVV+ + E S V KIKT Sbjct: 177 TAANSSGRATSTAELLVQGEEAMPTKKTKTVVSTS-EIRTSKARVQKIKT 225 Score = 58.0 bits (134), Expect = 3e-06 Identities = 45/201 (22%), Positives = 86/201 (42%), Gaps = 15/201 (7%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK------ATYENRX 1533 Q+PT +PL+++ G P P+V+W+RDG+ L A + + R Sbjct: 4 QAPTFTQPLQSVVALEGSAATFEAQVSGSPVPEVSWFRDGQVLSVAALPGVQISFSDGRA 63 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSC--VVGIQQKP---VITISNEDIKQKHKVGD 1588 Y A N G+ ++ +V ++ P V + + ++Q +V Sbjct: 64 VLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRL 123 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 + VT GIP P V +Y+ G ++++ ++ I + I E S Y++ A+ Sbjct: 124 DVRVT----GIPSPTVKFYREGAEIQSSADFQILQDGDLYSLLIAEAFPEDSGTYSVTAA 179 Query: 1649 NTAGTSSVEVTLKVYDKPSKP 1669 N++G ++ L V + + P Sbjct: 180 NSSGRATSTAELLVQGEEAMP 200 Score = 57.6 bits (133), Expect = 4e-06 Identities = 39/102 (38%), Positives = 54/102 (52%), Gaps = 6/102 (5%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK--SDGDTHSIT- 790 P + LK V +GE V L ++V +P P+I W NNK + KA + SD H T Sbjct: 3367 PSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTT 3426 Query: 791 --ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 I+ K KD G Y + A NSEG AE++A + V E++A Sbjct: 3427 SLIIDRVKEKDSGSYKVMAINSEGSAESTASLLVSMREEQSA 3468 Score = 57.2 bits (132), Expect = 5e-06 Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 2/138 (1%) Query: 464 EEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD 523 +EKG + L + Q +++ + P E + P V P + Sbjct: 1526 DEKGLIEETQLPEGRRAPQRMEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFE 1585 Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +F C+V GYP P++ W+ +I+ S+ ++++Y D + L I ++ D+G Sbjct: 1586 GDIARFRCRVTGYPAPKVNWYLNGQLIRKSKRYRLHY--DGIYYLEIVDIKSYDSGEVRV 1643 Query: 584 VAKNAAGFASSTTELIVE 601 VA N G T +L V+ Sbjct: 1644 VADNPLGTTEHTVKLEVQ 1661 Score = 56.4 bits (130), Expect = 8e-06 Identities = 99/469 (21%), Positives = 179/469 (38%), Gaps = 55/469 (11%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKPVK--ALPTKSDGDT 786 G+ PP ++PL V + +S+ A+V G P P + W C + V+ + + DGD+ Sbjct: 5169 GQGVPPAFLKPLMKKRVCENDSLTFFAEVFGLPSPEVKWFCNKTQLVEDDRIKMERDGDS 5228 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITV 844 S+T+L K D+G Y +A N+ G A + ++ V PP + E V Sbjct: 5229 ISLTVLDVTKA-DQGEYICEAVNNVGEARSVTLVVVLSQEMRLMPPPPAVTHQHVMEFDV 5287 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGD 903 ++ T + + + E + IT + +N ++ V ++ Sbjct: 5288 EDNDTSRSPSPQEILLEVELDENEVKEFEKQVKIITIPEYTADNKSMI---VSLDVLPSV 5344 Query: 904 YKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVILECQTSHTVS--TK 959 Y+ A + ++ +V ++ F+ + ET EG T++ EC T S Sbjct: 5345 YEEGAVDFVTHEHDDLKIAFEVTEMPPRFINPI-CDMETPEGTTILFECSLMGTPSPIVS 5403 Query: 960 WYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKE 1014 W+ K+I + + EG D GV C +V + + LVV Sbjct: 5404 WFKGDKKIPPNSKKYVHSSEGDNHILKICTVTTQDSGVYICRAINVVGETLSRASLVVVN 5463 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV---WERDGEIIKPKKNKYDFEKRGHI 1071 F + + EV V++ +I + D++ DGE + + +++F++ Sbjct: 5464 A-KAFAGRTRGREVTA--VSLRSAKIQPQKFDLMVGGTSLDGEQVSEIELEFEFDQEADE 5520 Query: 1072 RKLYI-------RNTSVHDEGE-YSCILRD------------------ESCTAEVTVVEL 1105 + + R + ++GE Y I D + C+ + V E Sbjct: 5521 SQRAVRLVANADRQSETSEQGEKYVSINFDVFAEPAKEEKVEFKGKSSDLCSFQFQVTES 5580 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHI 1152 PP+ I L N G + L G + W+KDG + S I Sbjct: 5581 PPKFIIPLTNITAAAGTPVILQC-LVSGTPNPTAEWYKDGGRVTDSRCI 5628 Score = 56.4 bits (130), Expect = 8e-06 Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 2/128 (1%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 ++++ +Y+ + N K+ K T +++M P F + LR G+ +C+V G Sbjct: 7369 EKSDSAEYIMQVSN-KVGKDECTCSLTVLDRTMPPTFTKPLRRVDANIGNDASLDCKVSG 7427 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 I WF+ I FQ + D + ATL I + D+G + C A N+AGF ++ Sbjct: 7428 SQPMTIAWFKDDHEITAGPKFQAGFKDHS-ATLQIAGLEKADSGVYKCRATNSAGFKETS 7486 Query: 596 TELIVEAP 603 L V+ P Sbjct: 7487 GTLYVKEP 7494 Score = 56.4 bits (130), Expect = 8e-06 Identities = 30/94 (31%), Positives = 48/94 (51%), Gaps = 2/94 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FVE L P G V +C+V G P +++WF+ ++ S ++ Y VA L Sbjct: 9300 PYFVESLEPMEVTAGDAVCLKCKVAGTPEIKVSWFKADGKVRSSPTCRLEY-TKGVACLK 9358 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEA 602 + + D G ++C A+N G SS+ L ++EA Sbjct: 9359 LSKATKADIGEYSCKAENRIGATSSSCRLNVLEA 9392 Score = 56.0 bits (129), Expect = 1e-05 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 3/145 (2%) Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 E V V + +E A PP I + +TV E ++ L ++ P P I W+R + I Sbjct: 574 EPQEVSAVPKAAQEPAVPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIE 633 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 S ++ LVI +E DSG + C A+N AG S + + V + + Sbjct: 634 SSIDFHTSYTDGIARLVIREAFAE-DSGRFSCTATNEAGTISTSCYLLVKVSEEIEYREE 692 Query: 935 QKSYETEEGKT--VILECQTSHTVS 957 + TE G T I C H V+ Sbjct: 693 PVAEVTEVGVTQEKICWCLIKHWVA 717 Score = 55.6 bits (128), Expect = 1e-05 Identities = 52/205 (25%), Positives = 83/205 (40%), Gaps = 30/205 (14%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-----------------QT 547 E+ P+FV K P +G T +F+ +V G P P WF QT Sbjct: 1101 ERLYKPVFVMKPTPLRCSEGQTARFDLKVVGRPMPDTYWFHNGEEKLDMFFSCTGLVLQT 1160 Query: 548 AIIKPSQDFQMYYD------DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + + Q Y +D V +L+I P+D+G +T +A+N AG S + L V+ Sbjct: 1161 SFFRTGQQVVSDYSHKIVIKEDGVQSLIIVPAMPKDSGEWTVIAQNRAGRTSVSITLTVD 1220 Query: 602 --APLSDHGSEMTVXXXXX----XXXXXXXADILEGIP-PTFSKKPKAQYVDEGSDILLE 654 + + S + + E + P F +K K V EG+ + L Sbjct: 1221 GKSEICPAASAPVMTRLPSGLGPNSFTWIQSPARESLTRPQFVEKLKNMTVKEGTLVELA 1280 Query: 655 CRLVAIPEPDIAWLFKGEEIVPDEN 679 + + P PDI WL + I P ++ Sbjct: 1281 VKAIGNPLPDIVWLKNSDIISPHKH 1305 Score = 55.6 bits (128), Expect = 1e-05 Identities = 36/123 (29%), Positives = 61/123 (49%), Gaps = 5/123 (4%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQV 533 D+ + +Y +N+ + K+ T +E+ P+F +K +H D G V+ E +V Sbjct: 9555 DKGDTGKYFCHAMND-VGKVSCSSDVTVKERKNPPVFTKK-PSEHMEDTEGRLVKIEGRV 9612 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G ++W+++ A I S + + + NVA L I+ D+G +TC A N AG AS Sbjct: 9613 SGSQPMSVSWYKEDAEIHSSDKYDISFKS-NVAVLCIKSSHVTDSGRYTCQASNEAGRAS 9671 Query: 594 STT 596 T Sbjct: 9672 CCT 9674 Score = 54.8 bits (126), Expect = 2e-05 Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G FECQV G P + WF++ + I PS+ +QM + +++A+L + +D+G + C Sbjct: 8165 GQNKVFECQVTGTPEIDVYWFKEGSEIHPSERYQMSF-LNSLASLEVCGTETKDSGLYYC 8223 Query: 584 VAKNAAGFASSTTELIVE 601 A+N AG S + EL V+ Sbjct: 8224 EARNEAGSESCSMELKVK 8241 Score = 53.6 bits (123), Expect = 6e-05 Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 7/147 (4%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL---EGIPPTFSKKPKAQYVDE 647 F+ L + A + H +V A++L E PP F ++ ++ V + Sbjct: 58 FSDGRAVLRLTAVTAAHSGRYSVRATNGAGQATSTAELLVTVETAPPNFVQRLQSSTVRQ 117 Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS + L+ R+ IP P + + +G EI + + + D++ L I GT Sbjct: 118 GSQVRLDVRVTGIPSPTVKFYREGAEIQSSADFQILQDGDLYS----LLIAEAFPEDSGT 173 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEP 734 Y+V A N G A+ L ++ E P Sbjct: 174 YSVTAANSSGRATSTAELLVQGEEAMP 200 Score = 52.8 bits (121), Expect = 1e-04 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 1/99 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +Q + P F KL+ S EC V G + W++ I+ + + + N Sbjct: 7959 DQIIPPSFTRKLKQTEGIKASFAHLECLVSGSLPITVHWYKDDKEIQADHKHKCTFFE-N 8017 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 VA L I ++ +D G++TC+AKN AG + L+V+ P Sbjct: 8018 VAFLEISDLDSKDGGSYTCIAKNKAGAVQCSAILLVKEP 8056 Score = 52.4 bits (120), Expect = 1e-04 Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 7/141 (4%) Query: 1453 AYAVNEVDISD--ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 A A++E + D E + K +E + PT+ LKN+T E + L C GG P Sbjct: 562 AVALSEEEFEDWEPQEVSAVPKAAQEPAVP-PTLIVGLKNVTVTEGESLTLECQIGGQPT 620 Query: 1511 PKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 P + W+R+ +++++ +Y + + C A N+ G + TSC + Sbjct: 621 PVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFSCTATNEAGTISTSCYLL 680 Query: 1567 IQQKPVITISNEDIKQKHKVG 1587 ++ I E + + +VG Sbjct: 681 VKVSEEIEYREEPVAEVTEVG 701 Score = 52.4 bits (120), Expect = 1e-04 Identities = 28/102 (27%), Positives = 53/102 (51%), Gaps = 3/102 (2%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 TS ++ P F +KL+ + +G V+ +C++ P P I WF + ++ ++ D Sbjct: 3359 TSGTGNVKPSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSD 3418 Query: 562 DD---NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + +L+I V +D+G++ +A N+ G A ST L+V Sbjct: 3419 SQMHMHTTSLIIDRVKEKDSGSYKVMAINSEGSAESTASLLV 3460 Score = 52.4 bits (120), Expect = 1e-04 Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 5/131 (3%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534 +D YT + ++ + + K+ + T ++ + P F KL+ HT G + EC+V Sbjct: 8988 LDSGEYTFEIMNEVGKDLSKINL----TVLDKIIPPSFSRKLKDCHTVVGKAGEMECKVS 9043 Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 G P I+W I+ ++++ + +N L + + D+G + C A N AG + + Sbjct: 9044 GSPPFAISWHHDGEEIQSGPNYEISF-SNNSCILRVPTLKLSDSGLYKCKAVNEAGTSET 9102 Query: 595 TTELIVEAPLS 605 + V+ P S Sbjct: 9103 AATMDVKEPPS 9113 Score = 51.6 bits (118), Expect = 2e-04 Identities = 19/54 (35%), Positives = 33/54 (61%) Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 ++ P E+ P F+ + + +TVKE ++L + NP+P I W +N++IISP Sbjct: 1249 IQSPARESLTRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISP 1302 Score = 51.6 bits (118), Expect = 2e-04 Identities = 31/106 (29%), Positives = 54/106 (50%), Gaps = 3/106 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+KL + GS V C ++G ++W + +K ++ Q+ Y + N A L Sbjct: 7775 PSFVQKLENLSSLVGSEVSLLCVLKGSEPMVVSWMKDNHELKEAEHIQITY-ESNTALLH 7833 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613 I +V AG ++C A+N AG + + L V+ P ++D ++V Sbjct: 7834 ITDVQRNHAGKYSCQAQNQAGSQTCSALLTVKEPAEITDEAKSISV 7879 Score = 51.2 bits (117), Expect = 3e-04 Identities = 61/316 (19%), Positives = 120/316 (37%), Gaps = 27/316 (8%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E P F KKP AQ + EG ++ EC++ P+P + W G + VA + + Sbjct: 736 ETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRETG 795 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK--------IKTGEKEP------- 734 C L+I+ G Y + N GE S L + +G P Sbjct: 796 E-CK-LEISMTFADDAGEYAIFVKNPHGEVSASASLLEEGTGTVLLSSGCHRPWLRGQGS 853 Query: 735 --PQVIEPLKSMIVRQGESVI---LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 V ++Q + ++ V+ P +T + + + S+ + I Sbjct: 854 TSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQMEQKQITTPVSVVSERE-FLI 912 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 + + + +++ + ++ E + E ++ E AE P F + + E Sbjct: 913 SAFEERIIQEIELRIMRITYRELVTEDRELMVTA--AEGEAEQPAFNTPVKNYRIMEGMG 970 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVA 908 + R++ P+P I W+++ + + PS+ + L + V E D G Y A Sbjct: 971 VTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLRLAQVLPE-DEGVYTAFA 1029 Query: 909 SNSAGKSSHGARVTID 924 +N G + ++ ++ Sbjct: 1030 ANVLGNAVSSGKLYVE 1045 Score = 50.8 bits (116), Expect = 4e-04 Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 4/103 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--I 791 PP +I LK++ V +GES+ L Q+ G P P I W + + +++ T I + Sbjct: 591 PPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLV 650 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSA--VITVEEPTEENAEP 832 ++ +D G ++ A N G TS ++ V E E EP Sbjct: 651 IREAFAEDSGRFSCTATNEAGTISTSCYLLVKVSEEIEYREEP 693 Score = 49.2 bits (112), Expect = 0.001 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+FV+++ P G +F CQ G P P +TW + + + DF + D N + L Sbjct: 4350 APVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDI-IDRANRSKL 4408 Query: 569 VIREVFPEDAGTFTCVAKNAAG--FASSTTEL 598 + + GT+ C+ N G S+T E+ Sbjct: 4409 TVFYPTADHEGTYDCIITNKHGKSLCSATLEI 4440 Score = 48.8 bits (111), Expect = 0.002 Identities = 35/135 (25%), Positives = 59/135 (43%), Gaps = 3/135 (2%) Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + E E +A V E P + + V E + RVT P P + Sbjct: 1545 RMEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFEGDIARFRCRVTGYPAPKVN 1604 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 WY N ++I S+ ++DG L I ++ S DSG+ + VA N G + H ++ + Sbjct: 1605 WYLNGQLIRKSKRYRLHYDG-IYYLEIVDIKS-YDSGEVRVVADNPLGTTEHTVKLEVQ- 1661 Query: 926 EKVTFVKHLQKSYET 940 +K F L+++ E+ Sbjct: 1662 QKEDFRSVLRRAPES 1676 Score = 47.6 bits (108), Expect = 0.004 Identities = 38/156 (24%), Positives = 63/156 (40%), Gaps = 7/156 (4%) Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 +T+ P+ TL +WYK ++ ++K+ + + L IR+C DQ Y V S Sbjct: 10023 VTINYPEITL--SWYKGTQKLDSSDKYDISISGDRHLLRIRRCQTSDQGNYRVVCGPHIS 10080 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 + KL V E + D K G TL + P +W N K ++ Sbjct: 10081 SAKLTVMEAEVEKHLQDTSG----KEGQSCTLSCQL-SIPNVQAQWFKNGKRLEMKGKFT 10135 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 + K L I ++ D G Y + ++ AD+ Sbjct: 10136 SEVKHKIQKLLISDLKPEDQGRYTCQYQSLESSADL 10171 Score = 46.8 bits (106), Expect = 0.007 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E P F+ K + EG + CR+ P P IAW G+ + P ++ + D Sbjct: 950 EAEQPAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGR 1009 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 + L++ V EG YT A N G A L ++ PPQ Sbjct: 1010 ---ASLRLAQVLPEDEGVYTAFAANVLGNAVSSGKLYVEPSGAFPPQ 1053 Score = 46.4 bits (105), Expect = 0.009 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 1/104 (0%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+ V+ ECQV I W R + S D ++ ++D VA + Sbjct: 7026 PSFVKPFDQASAAVNDPVRLECQVNEDTGVTIIWTRDGKKVHQSMDCKLSFED-KVAVVE 7084 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 I + +D+G + C A N AG +S ++V+ P S TV Sbjct: 7085 IPKAKLKDSGKYVCTATNEAGSSSCEAVVMVQEPPSIRKELQTV 7128 Score = 45.2 bits (102), Expect = 0.020 Identities = 18/38 (47%), Positives = 26/38 (68%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 PQ +E LK+M V++G V L+ + +GNP P I W KN+ Sbjct: 1260 PQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNS 1297 Score = 45.2 bits (102), Expect = 0.020 Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 4/106 (3%) Query: 1594 AVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 A + G+P PEV W+ N ++ + ++ T+ + I + H+ +YT A+N+A Sbjct: 3241 ACVSGMPKPEVSWFHNQRPIQPTTNVVFHFEEATNTATLIIVDAFTEHAGQYTCRAANSA 3300 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 G ++ TL + + E +++E ++ + + K P G E Sbjct: 3301 GEAACSATLTI--TKVQQEEVTVVKEQTQIQIQQDIKEPFHGSGSE 3344 Score = 45.2 bits (102), Expect = 0.020 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 8/124 (6%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE----NI 888 P F + + +V E ++L + +P PSI W+ NN+ + + D + Sbjct: 3367 PSFTKKLKFQSVLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTT 3426 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV---EKVTFVKHLQKSYETEEGKT 945 L+I V E DSG YK +A NS G + A + + + + ++ H +++ + ++ Sbjct: 3427 SLIIDRV-KEKDSGSYKVMAINSEGSAESTASLLVSMREEQSANYLSHARRAAKAQDSTA 3485 Query: 946 VILE 949 E Sbjct: 3486 TSAE 3489 Score = 45.2 bits (102), Expect = 0.020 Identities = 24/83 (28%), Positives = 38/83 (45%) Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K +VG+ T G P P V W K+G+ L N+ +++I + S + + H Sbjct: 4361 KARVGEMSEFTCQFHGDPLPTVTWLKDGHPLTNNPDFDIIDRANRSKLTVFYPTADHEGT 4420 Query: 1643 YTIEASNTAGTSSVEVTLKVYDK 1665 Y +N G S TL++ DK Sbjct: 4421 YDCIITNKHGKSLCSATLEIADK 4443 Score = 45.2 bits (102), Expect = 0.020 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 2/97 (2%) Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P FV KL G + + EC+ G P WF+ I P + M DD VA+L Sbjct: 7588 PTFVRKLEATTLVTCGQSSRLECRATGSPVIIFKWFKDEMEITPGPKYTMAADD-LVASL 7646 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 I + ++G + CVA + AG + V+AP S Sbjct: 7647 EIVQCTLAESGDYVCVASSEAGSDCCRGTVTVKAPPS 7683 Score = 44.8 bits (101), Expect = 0.026 Identities = 51/244 (20%), Positives = 87/244 (35%), Gaps = 22/244 (9%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVE--GYPRPQITWFRQTAIIKPSQDFQMYYD 561 +E+ P F +KL FEC++ G P + W ++ + +M + Sbjct: 1427 KEKQQKPQFKKKLTSIRMKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMV-N 1485 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--------EAPLSD------H 607 + +L + D+G TC A N G ++ LIV E L + Sbjct: 1486 EFGYCSLDYEVAYARDSGVITCRATNNFGIDQTSATLIVKDEKGLIEETQLPEGRRAPQR 1545 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667 E+ + E P P+ V EG CR+ P P + W Sbjct: 1546 MEELERVAHEGGPAGVSTDEEFEKTKPEIVLLPEPARVFEGDIARFRCRVTGYPAPKVNW 1605 Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 G+ I + + + +Y L+I ++K + G VVA N G + L++ Sbjct: 1606 YLNGQLIRKSKRYRLHYDG---IY--YLEIVDIKSYDSGEVRVVADNPLGTTEHTVKLEV 1660 Query: 728 KTGE 731 + E Sbjct: 1661 QQKE 1664 Score = 44.4 bits (100), Expect = 0.035 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+FV K P G F+C + G + W + I + M D N +L Sbjct: 6933 PVFVSKPEPMTLFVGKEAVFQCSLTGSSPMDVVWHKDNLAISSEGKYVM-KSDKNKYSLH 6991 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 I+ + G + C A N+ G A+ +TEL +++ P Sbjct: 6992 IQSLELAHQGVYLCKASNSVGTATFSTELWVIDKP 7026 Score = 42.7 bits (96), Expect = 0.11 Identities = 60/298 (20%), Positives = 114/298 (38%), Gaps = 32/298 (10%) Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 VA++ E + +++ GE P ++ + + +G SV+ QV GNP+P + W K Sbjct: 716 VALSVAVETKEQVTVEVSAGETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKK 775 Query: 771 NNKPVKA---LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 N P+ +T + + D G Y + +N G SA + +EE T Sbjct: 776 NGLPLTTGYRYRVAYKRETGECKLEISMTFADDAGEYAIFVKNPHGEVSASASL-LEEGT 834 Query: 827 ----------------EENAEPPLFINRFQEITVKEKGTIK--LVARVTRNPVPSITWYR 868 + + +F +++ + T K + V + P +T Sbjct: 835 GTVLLSSGCHRPWLRGQGSTSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQME 894 Query: 869 NNEIISPSETITQN--FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +I +P +++ E +I ++ I Y+ + + A + E Sbjct: 895 QKQITTPVSVVSEREFLISAFEERIIQEIELRIMRITYRELVTEDRELMVTAAEG--EAE 952 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REIIQEGR 980 + F + K+Y EG V C+ S K W+ + + + DH E +Q+GR Sbjct: 953 QPAFNTPV-KNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGR 1009 Score = 42.3 bits (95), Expect = 0.14 Identities = 29/98 (29%), Positives = 38/98 (38%), Gaps = 6/98 (6%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXXX 1535 +P K + + E E TC F G P P VTW +DG L T ++ NR Sbjct: 4350 APVFVKEMCPLKARVGEMSEFTCQFHGDPLPTVTWLKDGHPL-TNNPDFDIIDRANRSKL 4408 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 Y CI N HG+ S + I K V+ Sbjct: 4409 TVFYPTADHEGTYDCIITNKHGKSLCSATLEIADKIVV 4446 Score = 42.3 bits (95), Expect = 0.14 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 1/91 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F K+ GS+ +F C+V P W++ IK S+ +++ + A + Sbjct: 6838 PVFRLKIAALEINVGSSAKFYCEVSDAPDVNFRWYKSGVEIKQSEKYRIVSSSTSSALEL 6897 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + V D+G ++C N G + LIV Sbjct: 6898 VSPV-KADSGEYSCKVSNPHGVDTCAASLIV 6927 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 2/106 (1%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555 P P + ++ F+E+ + + ST F +V G P P + W + Sbjct: 9788 PAVAAPVKRQDNL--FFIEEPKAVRVTEKSTATFMTKVGGDPIPSVKWMKGKWRQMTHGG 9845 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 A L IREV D+G + C+A N G +++L+VE Sbjct: 9846 RISVDQKGQEAKLEIREVTRSDSGQYRCIASNKHGEIECSSDLLVE 9891 Score = 41.9 bits (94), Expect = 0.19 Identities = 87/445 (19%), Positives = 172/445 (38%), Gaps = 65/445 (14%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 +PP +I L+N V +G T E ++ + ++ WF++ +I+ S + +L Sbjct: 590 VPPTLIVGLKNVTVTEGESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARL 649 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 I + +D+ G CTA T E +I+ T YL V++ +E Sbjct: 650 VIREAFAEDS-------GRFSCTA--TNEAGTIS--------------TSCYLLVKVSEE 686 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 Y+++ V E TE ++ K +I+ V ++ K ++V Sbjct: 687 IE----YREEPVAEVTE--VGVTQEKICWCLIKHWVA------LSVAVETKEQVTVEVSA 734 Query: 1284 VEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DS 1340 E P + ++ G V P+P+ W N + + + ++ Sbjct: 735 GETAAPFFMKKPAAQKLVEGGSVVFECQVGGNPKPHVIWKKNGLPLTTGYRYRVAYKRET 794 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-------PSPPGKPNILEID 1393 L I DAG Y + ++N H +V + ++L++ S +P + Sbjct: 795 GECKLEISMTFADDAGEYAIFVKNP--HGEVSASASLLEEGTGTVLLSSGCHRPWLRGQG 852 Query: 1394 SSSINICWDEPEN-------TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 S+S ++ ++ E T + + V++ + T+ + K IT T S+ + + Sbjct: 853 STSASVFTEQYEAYMKQHDLTFKTEVTTTVIQEPAVIVTQ-MEQKQIT-TPVSVVSEREF 910 Query: 1447 SSYRFRAYAVNEVDISD--------ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 F + E+++ +E E E + + P P+KN Sbjct: 911 LISAFEERIIQEIELRIMRITYRELVTEDRELMVTAAEGEAEQPAFNTPVKNYRIMEGMG 970 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523 + C G P PK+ W++DG++L+ Sbjct: 971 VTFHCRMSGKPLPKIAWFKDGQRLR 995 Score = 41.5 bits (93), Expect = 0.25 Identities = 31/125 (24%), Positives = 50/125 (40%) Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 A ST +L V V PP V + +++GS V L V P P ++ I+ Sbjct: 89 ATSTAELLVTVETAPPNFVQRLQSSTVRQGSQVRLDVRVTGIPSPTVKFYREGAEIQSSA 148 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 + D SL I + D+G Y + N+ G A + + + + P K + Sbjct: 149 DFQILQDGDLYSLLIAEAFPEDSGTYSVTAANSSGRATSTAELLVQGEEAMPTKKTKTVV 208 Query: 1393 DSSSI 1397 +S I Sbjct: 209 STSEI 213 Score = 41.1 bits (92), Expect = 0.33 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P+V WYK +++ + I+ + + + +K LK+ S Y ASNT G + Sbjct: 5750 VSGDPVPDVKWYKGAFQVQPGRNCVIISNPDGSGCLSLKSLKQEDSGMYMCRASNTFGEA 5809 Query: 1655 SVEVTLKVY 1663 S L V+ Sbjct: 5810 SSSAELAVF 5818 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/94 (26%), Positives = 41/94 (43%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F +++ G+TV+ + V+G + W + + ++ D+NVA L Sbjct: 7212 PSFTKRVDSVTAVLGTTVKLQGTVKGSSPITVKWMKDSEYLRDDDPSITLTFDNNVAFLS 7271 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I V G + C A+N AG S L V+ P Sbjct: 7272 IATVAISHGGKYVCQAENEAGQQKSEATLTVQEP 7305 Score = 41.1 bits (92), Expect = 0.33 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +EK + GS V F + G P I WF+ I S D + D+ + +L Sbjct: 8057 PCILEKPESMNVLPGSKVHFNVLLSGTPPLTIKWFKNQKEILSSADCSVIKDNTS-TSLA 8115 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + D+G + C +N G S L V+ P Sbjct: 8116 LFFAKSSDSGEYRCEIQNDVGSTSCQATLFVKEP 8149 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 3/99 (3%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 SE P F + P G V C++ G Q+TWF+ + S+ ++M + Sbjct: 8729 SEAAVEPPSFTKVPEPMEGLKGKDVSLYCELAGTAPFQVTWFKDKKPLMESRKYKMLSEG 8788 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +V TL I + D G + C N+ G S T + +V+ Sbjct: 8789 SSV-TLHIIGLESTDIGQYECKVSNSVG--SDTCQTLVK 8824 Score = 40.3 bits (90), Expect = 0.57 Identities = 25/102 (24%), Positives = 53/102 (51%), Gaps = 4/102 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ + I G P P ++W++ ++E+ +++ + + + + I+E S +++ Sbjct: 606 GESLTLECQIGGQPTPVIMWFREDYQIESSIDFHTSYTDGIARLVIREAFAEDSGRFSCT 665 Query: 1647 ASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 A+N AGT +S + +KV ++ E PV E++ VT E Sbjct: 666 ATNEAGTISTSCYLLVKVSEEIEYREEPV--AEVTEVGVTQE 705 Score = 40.3 bits (90), Expect = 0.57 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P P+V WY NG + K Y + + + I ++K S + + A N GT+ Sbjct: 1595 VTGYPAPKVNWYLNGQLIRKSKRYRL-HYDGIYYLEIVDIKSYDSGEVRVVADNPLGTTE 1653 Query: 1656 VEVTLKVYDK 1665 V L+V K Sbjct: 1654 HTVKLEVQQK 1663 Score = 39.9 bits (89), Expect = 0.75 Identities = 19/91 (20%), Positives = 46/91 (50%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P +V W+K+ L ++Y + ++ + + I L+ + +Y + SN+ G+ + Sbjct: 8759 LAGTAPFQVTWFKDKKPLMESRKYKMLSEGSSVTLHIIGLESTDIGQYECKVSNSVGSDT 8818 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + +K+ + PS + M + + VT++ Sbjct: 8819 CQTLVKLREPPSFVKKLSNMTVVLGQEVTLQ 8849 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/94 (27%), Positives = 37/94 (39%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV + GS V F V+G ++ WFR ++P + N L Sbjct: 9112 PSFVVPPQSLEALPGSNVTFSAMVKGSAPLKLKWFRGAKEMEPGRTCSFSLTSTNQVMLE 9171 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + V AG +TC N AG S L ++ P Sbjct: 9172 LFNVDRSHAGEYTCQIINDAGKESWPVNLSIKEP 9205 Score = 38.7 bits (86), Expect = 1.7 Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F K + GSTV F G + WF++ I + + D + ++L Sbjct: 7495 PTFTVKPDGQDVIPGSTVSFRAAFTGTAPLTVKWFKEDKEIVSGGTYFIKKDATS-SSLE 7553 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 ++ V P D+ + C N AG T L V+ P Sbjct: 7554 LQAVKPSDSARYACQVSNDAGKVDCTALLFVKEP 7587 Score = 38.3 bits (85), Expect = 2.3 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQL-TIDGKKQKLK 1164 P T ++N ++ +G TF ++ K + WFKDG ++ S+H Q+ T+ + L+ Sbjct: 954 PAFNTPVKNYRIMEGMGVTFHCRMSGKPLPKIAWFKDGQRLRPSDHYQMETLQDGRASLR 1013 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 + +D G Y+ N Sbjct: 1014 LAQVLPEDEGVYTAFAAN 1031 Score = 38.3 bits (85), Expect = 2.3 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKY 1063 T P+F+ KL++ VKE + L V+ I + D+VW ++ +II P K+ + Sbjct: 1258 TRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISPHKHPH 1307 Score = 37.9 bits (84), Expect = 3.0 Identities = 18/58 (31%), Positives = 28/58 (48%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 + E P FVEKL+ +G+ V+ + G P P I W + + II P + + Y Sbjct: 1253 ARESLTRPQFVEKLKNMTVKEGTLVELAVKAIGNPLPDIVWLKNSDIISPHKHPHIKY 1310 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 4/76 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK----SASLTIKKVENTD 1354 + G V L + A P P+ W N+K + K + + DS+ + SL I +V+ D Sbjct: 3378 VLEGEPVELKCELVASPPPSILWFHNNKTLGKARRRRICSDSQMHMHTTSLIIDRVKEKD 3437 Query: 1355 AGIYKLRLENNCGHAD 1370 +G YK+ N+ G A+ Sbjct: 3438 SGSYKVMAINSEGSAE 3453 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 3/95 (3%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P +V+W K+G +L+ +E +TT EK + I+ ++ S + +Y++ A ++ S ++ Sbjct: 2838 PNIQVMWMKDGQELDLSEERYVTTAEKYVHRLMIQTVRMSDAGEYSVVAGSS--VSKAQL 2895 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 ++ D P + + + TIE++ DD Sbjct: 2896 VVEGRDIRIAPPAERDITVLEKHRATIEFEVNEDD 2930 Score = 36.3 bits (80), Expect = 9.2 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%) Query: 540 QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE-DAGTFTCVAKNAAGFASSTTEL 598 ++ W ++KP ++F+ + D TLVI +V E G + C A+N AG ++++ L Sbjct: 6772 KVNWLFNGQLVKPGKEFRCSKEKDTY-TLVISKVVKEMHQGEYVCEAENEAGKTTTSSRL 6830 Query: 599 IV 600 V Sbjct: 6831 TV 6832 >UniRef50_A2AT18 Cluster: Titin; n=11; Eukaryota|Rep: Titin - Mus musculus (Mouse) Length = 8268 Score = 266 bits (653), Expect = 3e-69 Identities = 273/1226 (22%), Positives = 500/1226 (40%), Gaps = 97/1226 (7%) Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528 +P+ + D+ YT ++ ++ + + V ++ + P FV +L+ G++V Sbjct: 3365 IPSAEMNDKGLYTFEVENRVGKSSCTVSVHVS----DRVVPPSFVRRLKDTSATLGASVV 3420 Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 EC+V G + WF I S Q + D NV TL + + P D G +TCVA N Sbjct: 3421 LECRVSGSAPISVGWFLDGNEIISSPKCQSSFAD-NVCTLTLSSLEPSDTGAYTCVAANV 3479 Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 AG S+ L V+ P S + +V ++L G+ TF+ V G Sbjct: 3480 AGQDESSAVLTVQEPPSFEQTPDSV-------------EVLPGMSLTFTS------VIRG 3520 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 + P + W E+V E ++++E + + L++ V+ Q G Y Sbjct: 3521 T-----------PPFKVKWFKGSRELVSGEACTISLED----FVTELELLEVEPGQSGDY 3565 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 + + N G AS L + KEP ++ L V G ++L A G P +++W Sbjct: 3566 SCLVTNDAGSASCTTHLFV----KEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSW 3621 Query: 769 CKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 KN P+ P T +IL+ ++D Y EN G A+++V Sbjct: 3622 MKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSV---- 3677 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 EPP FI + + I L +V P I+WY+ + + + F Sbjct: 3678 ---LEPPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNN 3734 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGK 944 LVI VD D G+Y C A NS G + A + I K+ +F + L+ +ET G Sbjct: 3735 VASLVINKVDHS-DVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHET-LGF 3792 Query: 945 TVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 V EC+ S + WY + + + + ++ VG C Sbjct: 3793 PVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSAS 3852 Query: 1003 D----QETSTMLVVKE-TIPEFI-RKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEI 1055 + +S L++ E +P F K ++ + + + + + W +D Sbjct: 3853 NPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNRE 3912 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIIT 1111 I+P N Y + L + + D G+Y+C + +SC+A++ V E PP I Sbjct: 3913 IRPGGN-YKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQE-PPRFIK 3970 Query: 1112 RLQNQKVNKGNKAT-FEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 +L ++ K ++ T +E ++ + V W+KD EIQ S+ +++ + L+++ Sbjct: 3971 KLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLS 4030 Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DET 1224 ++D+G+Y+CE G++ + L V+EP + P L A D +L E+ Sbjct: 4031 VEDSGDYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVETLKGA--DVHLECELQGTPP 4088 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEV 1283 V+W+K K + +K+ ++S+ ++ I D EY C D S T + Sbjct: 4089 FQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVT 4148 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN-SKIIKKCKHTKPSIDSKS 1342 ++ PP+ V + G +V L + + W + +I+++ + S Sbjct: 4149 MKAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENI 4208 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 A+L + E +AG Y +++N+ G + +++L+ + KP +++ + + C Sbjct: 4209 ATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEPAAIVEKPESIKVTTG--DTCTL 4266 Query: 1403 EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVD 1460 E +G + + + +E+ + + K I N+ S + N V Sbjct: 4267 ECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNPVG 4326 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 D+ + + + +I P+ + LK + + C G P V W+ DG Sbjct: 4327 -KDSCKVS----IQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGN 4381 Query: 1521 KLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 ++ + + +N Y CIA N G E S + +++ P + Sbjct: 4382 EISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSF-VQ 4440 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 D G T++++G PP V W+K +L N++ ++ + + ++ Sbjct: 4441 KPD-PMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVD 4499 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKV 1662 S S +YT SN AG +S L V Sbjct: 4500 TSQSGEYTCIVSNEAGRASCTTRLFV 4525 Score = 258 bits (632), Expect = 1e-66 Identities = 244/1080 (22%), Positives = 443/1080 (41%), Gaps = 53/1080 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KK +A G + L + WL +EI D+NI + E+++ Sbjct: 1146 PPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNV---- 1201 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L ++ ++ +G Y A N G +L +K EP ++E S+ V QG+ Sbjct: 1202 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK----EPATIMEEAVSIDVTQGDPA 1257 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810 L + G + W K+ + + P T +++ILK + KD G YT + +N Sbjct: 1258 TLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQND 1317 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G + A I V + PP F + +++ + I L V + SI W++++ Sbjct: 1318 VGRSSCKASINVLDLII----PPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDD 1373 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + IS S+ +F L I+ ++ DSG Y C A+N AG S +T+ E F Sbjct: 1374 QEISASDKHKFSFHDNTAFLEISQLEGT-DSGTYTCSATNKAGHSQCSGHLTVK-EPPYF 1431 Query: 931 VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 V+ Q S + G V L+ T ++ KW+ + KE+ R + ++ Sbjct: 1432 VEKPQ-SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFS 1490 Query: 989 XXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEV-KEKDVAILEVEIN-S 1042 D G C + + +T + VKE P+FI+K V + E ++ + Sbjct: 1491 AKAADSGTYICQLSNDVGTTSSKATIFVKEP-PQFIKKPSPVLVLRNGQSTTFECQVTGT 1549 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 V W DG I + KY + I N V + G Y C R+++ TA ++ Sbjct: 1550 PEIRVSWYLDGNEITDLR-KYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSI 1608 Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDG 1158 V+ PP I L+ +V K + E E+ V W K+ EI+ ++ Sbjct: 1609 ELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKM 1668 Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 L I CD D GEY C E G+ C+A + ++EP +F ++ V ++ Sbjct: 1669 SVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVALKEPP-SFIKKIENVTTVLKSSAT 1727 Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 + + + +TW K ++E+ + + + TL +R YTC + Sbjct: 1728 FQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKNES 1787 Query: 1275 STTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + + V+ P +I++ + + VTL P+ +W+ + K I ++ Sbjct: 1788 GIERCYAFLLVQEPAQIIEKAKSVDVTEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRY 1847 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNILEI 1392 S ++ AS I+ V D+G Y ++EN+ G + + + +LD+ PP + ++ Sbjct: 1848 FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKM 1907 Query: 1393 DSSSINICWDEPENTGNSTI-IYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYR 1450 D + E + +G+ I + + +EI T+ ++ V + + NL+ + Sbjct: 1908 DKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHENTVSLEVSNLELEDTAN 1967 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 + N + S I K + KP + P+ +E + G P Sbjct: 1968 YTCKVSNVAGDNACSG-------ILTVKEPPSFLVKPERQQAI-PDSTVEFKAVLKGTPP 2019 Query: 1511 PKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 K+ W +D +L + + + Y C ND G + ++ Sbjct: 2020 FKIKWLKDDVELVSGPKCFIGLEGSTSFLNLYSVDSSKTGQYTCQVTNDVGSDSCTTMLL 2079 Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 + + P + + + K GD + I G P +V+WY+N ++L +Y +T + Sbjct: 2080 VTEPPKF-VKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDS 2138 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 +VI++ L S + EA N AG++S + V + P P I+ + V++E Sbjct: 2139 VAVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNTEVSLE 2198 Score = 257 bits (630), Expect = 2e-66 Identities = 267/1184 (22%), Positives = 466/1184 (39%), Gaps = 67/1184 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P V L+ T +G +F+CQV G +++W+ + IKPS+ F+M +D L Sbjct: 6 PAIVTPLQDTVTSEGRPARFQCQVSGTDL-KVSWYCKDKKIKPSRFFRMTQFEDTYQ-LE 63 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I E +PED GT+ VA NA G SST L +EAP S ++ Sbjct: 64 IAEAYPEDEGTYAFVANNAVGQVSSTATLRLEAPES-----------ILHERIGQQIEME 112 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 P ++ + V G C + P W G EI + S+ + Sbjct: 113 MKAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSN--- 169 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 Y S L+I + G YT A N G S L + E PP + K++ G Sbjct: 170 -YVSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT--EAYPPTFLSRPKALTTFVG 226 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKA 807 ++ V G P I W K+ + P +D D L V+D G+Y+ KA Sbjct: 227 KAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKA 286 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G A +T+ + P FI + + I L +V + +ITW Sbjct: 287 SNKFGADICQAELTI-------IDKPHFIKELEAVQSAINKKIHLECQVDEDRKVTITWS 339 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ + + + F+ + L I + DSG Y C ASN AG SS A V + E Sbjct: 340 KDGQKLPAGKDYKIYFEDKIASLEIPLAKLK-DSGTYTCTASNEAGSSSSSAAVAVR-EP 397 Query: 928 VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 +FVK + SY G++ L C+ S + W+ N KE+S + + Sbjct: 398 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILD 457 Query: 986 XXXXXXXDVGVIKC----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI- 1040 D G C V ST +V+KE P FI+ L+ ++ A+L+ EI Sbjct: 458 ITDVKVDDSGTYSCEATNDVGSDSCSTEVVIKEP-PSFIKTLEPADIVRGANALLQCEIA 516 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTA 1098 + +V W +D + I+ K KY + L I + + D G+Y C++ +E C Sbjct: 517 GTGPFEVNWFKDKKQIRSSK-KYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGC 575 Query: 1099 EVT-VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI 1156 T +++ PP + ++ + G T + + + + V W K I+ I+++ Sbjct: 576 VATHLLKEPPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSF 635 Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 L I D + G+Y+C E G+ L V+EP+ + E I V A Sbjct: 636 SNGVAVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPA--KIIERAELIQVTAGD 693 Query: 1213 DAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 A L + L WYK + ++K+ + L D +YT + Sbjct: 694 PATLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEIS 753 Query: 1272 D----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + + T V + P R G L W + K Sbjct: 754 NEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKE 813 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 + + + +ASL I +V+ DAG + R N+ G D + + + PS KP Sbjct: 814 LTASDRYQIAFVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKP 873 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 ++ S + + TI ++ + + + K +++ + +KT+ Sbjct: 874 GSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSD 933 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 S + N + S +KE + +EK + + + +L C G Sbjct: 934 SGTYTCKVSNVAGSVECSADL----FVKE---PATFIEKLEPSQLLKKGDGTQLACKVTG 986 Query: 1508 VPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 P K+TW+ + ++L+ + K ++ E+ Y C A N+ G + Sbjct: 987 TPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTG 1046 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 +V +++ P T + I+ + + ++ A + G PP E+ W+K+ L + ++Y Sbjct: 1047 IVIVKESPYFTKEFKSIEVLKEY--DVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFL 1104 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +++ +++ + + + +Y +N G+S+ + + + PS Sbjct: 1105 QDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPS 1148 Score = 254 bits (621), Expect = 3e-65 Identities = 252/1096 (22%), Positives = 449/1096 (40%), Gaps = 74/1096 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + E PPTF +PKA G C + P +I W G + P + V + Sbjct: 206 VTEAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRVTDADN 265 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 H L+++N+ G Y+ A N+ G L I + P I+ L+++ Sbjct: 266 KHS----LELSNLTVQDRGIYSCKASNKFGADICQAELTI----IDKPHFIKELEAVQSA 317 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK-P-KKVKDEGVYTL 805 + + L QV + + TITW K+ + + A I L+ P K+KD G YT Sbjct: 318 INKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKIYFEDKIASLEIPLAKLKDSGTYTC 377 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSI 864 A N G + +SA + V EPP F+ + + G + +L ++ +PV + Sbjct: 378 TASNEAGSSSSSAAVAVR-------EPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQV 430 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TW++NN+ +S S T+ +F L IT+V + DSG Y C A+N G S V I Sbjct: 431 TWFKNNKELSESNTVRMSFVNSEAILDITDVKVD-DSGTYSCEATNDVGSDSCSTEVVIK 489 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXX 982 E +F+K L+ + + G +L+C+ + T W+ +KK+I + + Sbjct: 490 -EPPSFIKTLEPA-DIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKKYRLFTQKTFV 547 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVE 1039 DVG +C+V ++ V + P F++K+ DF L+ Sbjct: 548 YLEISSFNSADVGDYECVVANEVGKCGCVATHLLKEPPTFVKKVDDFTALAGQTVTLQAA 607 Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--- 1095 + SE V+W + E+IK + K + L I + + G+Y+C+ +E+ Sbjct: 608 VRGSEPISVMWMKGQEVIK-EDGKIKMSFSNGVAVLTIPDVQISLGGKYTCLAENEAGSQ 666 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 + +V+ P +II R + +V G+ AT E ++ L +W+KDG + S ++ Sbjct: 667 TSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGTPELKPKWYKDGRPLVASKKYRI 726 Query: 1155 TIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSIN--FT--LRLPEFI 1206 + +LK Y +L D+G+Y S EVG+S C TV + I FT LR + + Sbjct: 727 SFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPLFTKPLRNVDSV 786 Query: 1207 LVPA-NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 + A D + +P + V+W+K + ++++ + +L I + +D Sbjct: 787 VGGACRLDCKIAGSLP---MRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGN 843 Query: 1266 YTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 +TC ++ S +V+ PP V + GS V L +Q +W Sbjct: 844 FTCRATNSVGSKDSSGALIVQEPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKWFKG 903 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTIL 1378 K + + ++ +SL + V+ +D+G Y ++ N G + V+ T + Sbjct: 904 DKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSVECSADLFVKEPATFI 963 Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ 1437 +K P +L+ + C + TG I I + +E+ + + T Sbjct: 964 EKLEP---SQLLKKGDGTQLAC----KVTGTPPIKITWFANDRELRESSKHKMSFAESTA 1016 Query: 1438 T-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + ++ S + A NE S+ ++KE SP K K+I Sbjct: 1017 VLRLTDVAIEDSGEYMCEAQNEA----GSDHCTGIVIVKE----SPYFTKEFKSIEVLKE 1068 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY--ENRXXXXXXXXXXXXXXXYKCIA 1552 D+ L G P ++TW++D L++ + T+ + Y+C Sbjct: 1069 YDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVAADAGEYQCRV 1128 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N+ G S V +++ P E G A ++G P V W K+ ++ Sbjct: 1129 TNEVGSSTCSARVTLREPPSFIKKIEATSSLR--GGTAAFQATLKGSLPITVTWLKDNDE 1186 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + D +T + + + + ++ H KY +A N AG L V + + E Sbjct: 1187 ITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIMEEA 1246 Query: 1673 VIMREISRESVTIEWK 1688 V + + T++ K Sbjct: 1247 VSIDVTQGDPATLQVK 1262 Score = 253 bits (620), Expect = 3e-65 Identities = 292/1267 (23%), Positives = 489/1267 (38%), Gaps = 72/1267 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P TF KK V+ G I+LE + W G I P E ++ C Sbjct: 2646 PATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKT---C 2702 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +L+I + K G Y+ N G + ++ EPP + L+ + G+SV Sbjct: 2703 -ILEILSSTKGDAGHYSCEIENEAGRDACDALVSTL----EPPYFVTELEPLEASVGDSV 2757 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810 L QV G P T++W K + +++ P T+++ L KV D G YT AENS Sbjct: 2758 SLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENS 2817 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A + + ++E PP F + ++I + L R+ + + WYR+ Sbjct: 2818 IGTAASKTIFRIQE----RQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG 2873 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT 929 ++ E + +F L I D SG Y C ASN G +S AR+T + +K Sbjct: 2874 VLLRDDENLQMSFVDNVATLKILQTDLS-HSGQYSCSASNPLGTASSTARLTAREPKKSP 2932 Query: 930 FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F S + G++ EC + + W + KEI + I G Sbjct: 2933 FFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRIL 2992 Query: 988 XXXXXDVGVIKC-----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-LEVEIN 1041 D G C + KD S L VKE P+FI+KL +V ++ +I LE +I+ Sbjct: 2993 KVGKGDSGQYTCQATNDVGKDM-CSAQLSVKEP-PKFIKKLDASKVAKQGESIQLECKIS 3050 Query: 1042 -SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESC 1096 S VVW R+ + + KY+ + L I S D G+Y C D SC Sbjct: 3051 GSPEIKVVWFRNDSELH-ESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASC 3109 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 + + V + PP + KG+ + E++ V W KD +++ S ++T Sbjct: 3110 STALKV-KAPPVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKIT 3168 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 L I++ + D GEY C EVG+ C + +EP F +L + + + Sbjct: 3169 SKNFDTSLHIFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPP-RFVKKLSDASTLIGD 3227 Query: 1212 TDAYLTVEIPDETLDVTWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 V + + V W K K VI ++E + TL + +Y C + Sbjct: 3228 PVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQI 3287 Query: 1271 L-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 DA V V P IV+ + G+ TL P+ + +W + + + Sbjct: 3288 KNDAGMRECSAVLTVLEPATIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELS 3347 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + ASL I E D G+Y +EN G + ++V + D+ PP Sbjct: 3348 SGSRHHITFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRR 3407 Query: 1390 LEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTN 1446 L+ S+++ E +G++ I + + ++ EI ++ T ++ +L+ + Sbjct: 3408 LKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPS 3467 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 + + A N ++S T + P+ E+ ++ P + T + Sbjct: 3468 DTGAYTCVAANVAGQDESSAVL--------TVQEPPSFEQTPDSVEVLPGMSLTFTSVIR 3519 Query: 1507 GVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETS 1562 G P KV W++ ++L + +A + E+ Y C+ ND G S Sbjct: 3520 GTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSA--S 3577 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 C + K T + G ++ A G PP V W KN L IT Sbjct: 3578 CTTHLFVKEPATFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGIT 3637 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 T EK+S++ I E ++Y N AG E + V + P E + E Sbjct: 3638 TTEKSSILEILESTIEDYAQYACLIENEAGQDICEALVSVLEPPYFIEPLEHVEAAIGEP 3697 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 +T++ K DG E+ ++H + +V + I K++ + + Sbjct: 3698 ITLQCKV---DGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCK 3754 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP--II 1800 A+N VG S +VIK PS + + F NG P + Sbjct: 3755 AENSVG--AVASSAVLVIKERKLPPS---FARKLKDVHETLGFPVAFECRINGSEPLQVS 3809 Query: 1801 DYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 YK E+ ++ + +I + + Q+ A N +GT+ +S K+ + Sbjct: 3810 WYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTA---SSSAKLIL 3866 Query: 1860 GKTLTPP 1866 + PP Sbjct: 3867 SEHEVPP 3873 Score = 252 bits (618), Expect = 6e-65 Identities = 290/1262 (22%), Positives = 515/1262 (40%), Gaps = 82/1262 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+F+++ K G + L CRL + W G + DEN+ ++ ++ Sbjct: 2834 LPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFVDNV--- 2890 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + LKI G Y+ A N G AS L + +K P I+P+ S+ V GES Sbjct: 2891 -ATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIKPV-SIDVIAGES 2948 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V G +TW K+NK ++ G+T + ILK K D G YT +A Sbjct: 2949 ADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK-GDSGQYTCQAT 3007 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWY 867 N G SA ++V+ EPP FI + V ++G +I+L +++ +P + W+ Sbjct: 3008 NDVGKDMCSAQLSVK-------EPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWF 3060 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 RN+ + S +F ++ L+ N S D+GDY C A N G +S + + Sbjct: 3061 RNDSELHESWKYNMSF-VNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPP 3119 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 V K +G VIL+C+ S T W ++K++ +I + Sbjct: 3120 VFTQK--PPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLH 3177 Query: 986 XXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D+G C ++ +T V + P F++KL D D L+ + Sbjct: 3178 IFNLEAPDIGEYHCKATNEVGSDTCACTVKFKEPPRFVKKLSDASTLIGDPVELQAVVEG 3237 Query: 1043 -ETADVVWERD-GEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---- 1095 + VVW +D GE+I+ +N + F +I L + + G+Y C +++++ Sbjct: 3238 FQPISVVWLKDKGEVIRESENVRISFV--DNIATLQLGSPEASQSGKYVCQIKNDAGMRE 3295 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 C+A +TV+E P I+ + + V GN T E + L +WFKDG E+ + + Sbjct: 3296 CSAVLTVLE-PATIVEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHI 3354 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSI--NFTLRLPEFILV 1208 T LKI +++D G Y+ E VG S CT + V + + +F RL + Sbjct: 3355 TFVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKD---T 3411 Query: 1209 PANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 A A + +E + V W+ + I + K TL + D Sbjct: 3412 SATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNVCTLTLSSLEPSDTGA 3471 Query: 1266 YTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 YTCV + A V V+ PP + G +T + P +W Sbjct: 3472 YTCVAANVAGQDESSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKG 3531 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 S+ + + S++ L + +VE +G Y + N+ G A ++ + + + Sbjct: 3532 SRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKEPATFV 3591 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNL 1443 + +++ S + T ++ + EY + IT T+ +SI + Sbjct: 3592 KRLADTSVETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNC----GITTTEKSSILEI 3647 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 ++ + YA ++ + E + ++ P +PL+++ E I L C Sbjct: 3648 LESTIEDYAQYAC-LIENEAGQDICEALVSV----LEPPYFIEPLEHVEAAIGEPITLQC 3702 Query: 1504 IFGGVPQPKVTWYRDGKKLKTA---KATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 G P+ +++WY++ KL++A K ++N Y C A N G V Sbjct: 3703 KVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAV 3762 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHK-VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 +S V+ I+++ + +K H+ +G I G P +V WYK+G L++D Sbjct: 3763 ASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDAN 3822 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT--SSVEVTLKVYDKPSKPE-GPVIM 1675 ++ + ++I + +SH +Y ASN GT SS ++ L ++ P + PV + Sbjct: 3823 LQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSV 3882 Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 ES + + +++T +A + E K+ V+ + T + K+ + Sbjct: 3883 DLALGESGSFKCH-VTGTAPIKIT-WAKDNREIRPGGNYKMTLVE-NTATLTVLKVAKGD 3939 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 + A N G + + + P I + Y + K G Sbjct: 3940 AGQYTCYASNVAG------KDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRY--ECKIG 3991 Query: 1796 GSP---IIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851 GSP ++ YK E++ QE K++ + LS+ + + ARN G++ Sbjct: 3992 GSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSS 4051 Query: 1852 TS 1853 TS Sbjct: 4052 TS 4053 Score = 252 bits (617), Expect = 8e-65 Identities = 257/1083 (23%), Positives = 427/1083 (39%), Gaps = 61/1083 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +K + V G LEC++ PE + W G+ + + + + + Sbjct: 2364 PAVIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKI---- 2419 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S LKI +V+K GTYT N G++S V+ + + PP LK G S Sbjct: 2420 SSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDV-SDRMVPPSFTRRLKDTGGVLGTSC 2478 Query: 753 ILSAQVVGNPRPTITWC-KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810 IL +V G+ +I W + K V ++ + T+ L D G YT A N Sbjct: 2479 ILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANV 2538 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G E A++TV+EP P F+ + + V I + + P + W+R Sbjct: 2539 AGSDECRALLTVQEP-------PSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGA 2591 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + F+ EL + N+D SG+Y CV SN+AG++S R+ + E TF Sbjct: 2592 RELVKGNRCNIYFEDTVAELELFNIDIS-QSGEYTCVVSNNAGQASCTTRLFVK-EPATF 2649 Query: 931 VKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 VK L + E GK++ILE + T +S W + I+ + I+ + Sbjct: 2650 VKKLS-DHSVEPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILS 2708 Query: 989 XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSET 1044 D G C ++++ + LV P F+ +L+ E D L+ ++ + Sbjct: 2709 STKGDAGHYSCEIENEAGRDACDALVSTLEPPYFVTELEPLEASVGDSVSLQCQVAGTPE 2768 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV- 1103 V W + G+ +Y ++ L S++D GEY+C+ + TA + Sbjct: 2769 ITVSWFK-GDTKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIF 2827 Query: 1104 -----ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID 1157 +LPP +L++ + G T L + V W++DG ++ ++Q++ Sbjct: 2828 RIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSFV 2887 Query: 1158 GKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN--FTLRLPEFILVPAN 1211 LKI DL +G+YSC +G + TA LT EP + F ++ P I V A Sbjct: 2888 DNVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREPKKSPFFDIK-PVSIDVIAG 2946 Query: 1212 TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 A + + + VTW K I +T+ L I K + D +YTC Sbjct: 2947 ESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQA 3006 Query: 1271 LD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 + K ++ V E P I + K+G + L P+ W N + Sbjct: 3007 TNDVGKDMCSAQLSVKEPPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSEL 3066 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 + S + A LTI + D G Y N G A + + P KP Sbjct: 3067 HESWKYNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKPP 3126 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNS 1447 + S I E T +++ Q + ++ I+ KN T I NL+ Sbjct: 3127 PVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFD-TSLHIFNLEAPD 3185 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + A NEV SD T +K + P K L + +T + +EL + G Sbjct: 3186 IGEYHCKATNEVG-SDTCACTVKFK-------EPPRFVKKLSDASTLIGDPVELQAVVEG 3237 Query: 1508 VPQPKVTWYRD-GKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 V W +D G+ ++ ++ + +N Y C ND G E S Sbjct: 3238 FQPISVVWLKDKGEVIRESENVRISFVDNIATLQLGSPEASQSGKYVCQIKNDAGMRECS 3297 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 V+ + + I E + G+ + + V+ G P W+K+G +L + ++IT Sbjct: 3298 AVLTVLEPATIVEKPEPMTVT--TGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHIT 3355 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 + ++I + + YT E N G SS V++ V D+ P +R + S Sbjct: 3356 FVRNLASLKIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPS---FVRRLKDTS 3412 Query: 1683 VTI 1685 T+ Sbjct: 3413 ATL 3415 Score = 252 bits (616), Expect = 1e-64 Identities = 279/1212 (23%), Positives = 498/1212 (41%), Gaps = 106/1212 (8%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 VEK P G+ EC V G P WF+ + + + N+A+L I Sbjct: 3309 VEKPEPMTVTTGNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVR-NLASLKIPS 3367 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 D G +T +N G +S T +S H S+ V Sbjct: 3368 AEMNDKGLYTFEVENRVGKSSCT--------VSVHVSDRVV------------------- 3400 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F ++ K G+ ++LECR+ + W G EI+ + ++ C Sbjct: 3401 PPSFVRRLKDTSATLGASVVLECRVSGSAPISVGWFLDGNEIISSPKCQSSFADNV---C 3457 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L +++++ G YT VA N G+ VL + +EPP + S+ V G S+ Sbjct: 3458 T-LTLSSLEPSDTGAYTCVAANVAGQDESSAVLTV----QEPPSFEQTPDSVEVLPGMSL 3512 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810 ++ + G P + W K ++ + + + +T L+ +V+ G Y+ N Sbjct: 3513 TFTSVIRGTPPFKVKWFKGSRELVSGEACTISLEDFVTELELLEVEPGQSGDYSCLVTND 3572 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A + + V+EP F+ R + +V+ I L A + P S++W +N Sbjct: 3573 AGSASCTTHLFVKEPA-------TFVKRLADTSVETGSPIVLEATYSGTPPISVSWMKNE 3625 Query: 871 EII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + SP+ IT +E++ + ++ D Y C+ N AG+ A V++ +E Sbjct: 3626 YPLSQSPNCGITTTEKSSILEILESTIE---DYAQYACLIENEAGQDICEALVSV-LEPP 3681 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 F++ L+ E G+ + L+C+ T + WY ++ ++ + Sbjct: 3682 YFIEPLE-HVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 3740 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILEVEI 1040 DVG C ++ +S +LV+KE P F RKL+D E I Sbjct: 3741 NKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLKDVHETLGFPVAFECRI 3800 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 N SE V W +DGE++K N H+ L I T G+Y+C + TA Sbjct: 3801 NGSEPLQVSWYKDGELLKDDAN-LQMSFVHHVATLQILQTDQSHVGQYNCSASNPLGTAS 3859 Query: 1100 ------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151 ++ E+PP + + + G +F+ +T G A ++ W KD EI+ + Sbjct: 3860 SSAKLILSEHEVPPFFDLKPVSVDLALGESGSFKCHVT-GTAPIKITWAKDNREIRPGGN 3918 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 ++T+ L + DAG+Y+C G C+A L V+EP F +L + + Sbjct: 3919 YKMTLVENTATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQLGVQEPP-RFIKKLDQSRI 3977 Query: 1208 VPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 V D Y E + V WYK + I+++ KF + + L + + +D Sbjct: 3978 V--KQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSG 4035 Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 +YTC +A + + V+ PP +G+DV L + Q P W Sbjct: 4036 DYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHK 4095 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + ++ K K ++ S+ I V+ D G Y+ + N+ G +VT+ P Sbjct: 4096 DKRELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKAPPQF 4155 Query: 1384 PGK-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISV-KNITKTQTS 1439 K +I I + + E ++ ++ + + + ++ WIS +NI Q S Sbjct: 4156 VKKLTDISTIIGKEVQL-QTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFS 4214 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 + ++ ++ N+ + + T V++ I VEKP ++I + Sbjct: 4215 --RAEPANAGKYTCQIKNDAGMQECYAT---LSVLEPAAI----VEKP-ESIKVTTGDTC 4264 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXX-XXXXXYKCIAFND 1555 L C G P+ W++DGK+L + K ++ N+ Y N Sbjct: 4265 TLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQNP 4324 Query: 1556 HGEVETSCVVGIQ-QKPVITIS-NEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612 G + SC V IQ +I S +K+ + + G ++ + G PP V+W+ +GN+ Sbjct: 4325 VG--KDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNE 4382 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + + ++Y T + T + + L+ + + YT A+N AG+ L V + PS + P Sbjct: 4383 ISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKP 4442 Query: 1673 VIMREISRESVT 1684 M ++ +VT Sbjct: 4443 DPMDVLTGSNVT 4454 Score = 250 bits (613), Expect = 2e-64 Identities = 279/1201 (23%), Positives = 480/1201 (39%), Gaps = 96/1201 (7%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ + P F KL+ H G V FEC++ G Q++W++ ++K + QM + Sbjct: 3771 KERKLPPSFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSF-VH 3829 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 +VATL I + G + C A N G ASS+ +LI LS+H Sbjct: 3830 HVATLQILQTDQSHVGQYNCSASNPLGTASSSAKLI----LSEH---------------- 3869 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +PP F KP + + G +C + I W EI P N + Sbjct: 3870 -------EVPPFFDLKPVSVDLALGESGSFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 3922 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-K 742 + + + L + V K G YT A N G+ S L G +EPP+ I+ L + Sbjct: 3923 LVEN----TATLTVLKVAKGDAGQYTCYASNVAGKDSCSAQL----GVQEPPRFIKKLDQ 3974 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDE 800 S IV+Q E ++ G+P + W K+ ++ S D+ +I + V+D Sbjct: 3975 SRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDS 4034 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 G YT +A N+ G A +S + V+ EPP+F + + + + L + P Sbjct: 4035 GDYTCEARNAAGSASSSTSLKVK-------EPPVFRKKPFPVETLKGADVHLECELQGTP 4087 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 ++W+++ + + + + I NVD+ D G+Y+C A+N G + Sbjct: 4088 PFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDT-ADIGEYQCKATNDVGSDTCVGS 4146 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEI-SGMDHREIIQ 977 VT+ FVK L T GK V L+ + + +S W+ +K EI D+ I Sbjct: 4147 VTMKAPP-QFVKKL-TDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWISY 4204 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 + G C +K+ QE L V E + K + +V D Sbjct: 4205 SENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEP-AAIVEKPESIKVTTGDT 4263 Query: 1034 AILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 LE ++ + W +DG+ + NKY + L I N D G YS ++ Sbjct: 4264 CTLECTVSGTPELSTKWFKDGKEL-TSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEVQ 4322 Query: 1093 D----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSE 1145 + +SC + V + +PP +L+ G+ E ++ + V WF DG+E Sbjct: 4323 NPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNE 4382 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201 I Q T+ L + + DAG+Y+C G+ +C+A LTV EP Sbjct: 4383 ISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQKP 4442 Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 P +L +N + ++ V+W+K + + + + L + Sbjct: 4443 DPMDVLTGSNV-TFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTS 4501 Query: 1262 DQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 EYTC++ + A TT+L V+ P V +Y I++G + L + P Sbjct: 4502 QSGEYTCIVSNEAGRASCTTRL---FVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPI 4558 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + W N + + + KSA L I D+G Y +EN G + I Sbjct: 4559 SVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILI 4618 Query: 1378 LDKPSPPGKPNILEI---DSSSINICWDEPENTGNSTIIYYVVEYQEIDT-TEWISVKNI 1433 L+ P + +++ DS+S+ C + T + +Y + + T T + KN Sbjct: 4619 LEPPYFVKQLEPVKVTVGDSASLQ-C--QLAGTPEIGVSWYKGDTKLRPTATCKMHFKNN 4675 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 T Q + ++ S + A N V + S +T + ++E K+ P+ + L+++ Sbjct: 4676 VATLVFTQ-VDSSDSGEYICRAENSV--GEVSSST--FLTVQEQKL-PPSFSRQLRDVQE 4729 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYK 1549 + C G V+WY+DGK LK + + +N Y Sbjct: 4730 TVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYS 4789 Query: 1550 CIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 C A N G + ++ + K VG+ + + G P +V W K Sbjct: 4790 CTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAK 4849 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + ++ + Y I+ E ++ + I ++ + S +YT A N G S L + ++ Sbjct: 4850 DNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP 4909 Query: 1669 P 1669 P Sbjct: 4910 P 4910 Score = 248 bits (607), Expect = 1e-63 Identities = 253/1080 (23%), Positives = 436/1080 (40%), Gaps = 76/1080 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + EG +C+ V+ + ++W K ++I P + D + Sbjct: 5 PPAIVTPLQDTVTSEGRPARFQCQ-VSGTDLKVSWYCKDKKIKPSRFFRMTQFEDTYQ-- 61 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---------------KEPPQV 737 L+I EGTY VA N G+ S L+++ E K P + Sbjct: 62 --LEIAEAYPEDEGTYAFVANNAVGQVSSTATLRLEAPESILHERIGQQIEMEMKAAPVI 119 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794 ++ + V G + ++ G P W K + + +S S+ IL+ Sbjct: 120 KRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLEILRT 179 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 + V D G YT KA N G +A +TV E A PP F++R + +T K + Sbjct: 180 QVV-DCGEYTCKASNEYGSVSCTATLTVTE-----AYPPTFLSRPKALTTFVGKAAKFLC 233 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V+ PV I W ++ +SPS L ++N+ + D G Y C ASN G Sbjct: 234 TVSGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQ-DRGIYSCKASNKFGA 292 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMD 971 A +TI ++K F+K L+ + ++ K + LECQ V+ W + +++ +G D Sbjct: 293 DICQAELTI-IDKPHFIKELE-AVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKD 350 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQ-DF 1026 ++ I E + D G C ++ +S + V+E P F++K+ + Sbjct: 351 YK-IYFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREP-PSFVKKVDPSY 408 Query: 1027 EVKEKDVAILEVEIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 + + A L ++ S V W ++ E+ + + F I L I + V D Sbjct: 409 LMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAI--LDITDVKVDDS 466 Query: 1085 GEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139 G YSC ++ SC+ EV + E PP I L+ + +G A + E+ G V W Sbjct: 467 GTYSCEATNDVGSDSCSTEVVIKE-PPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNW 525 Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195 FKD +I+ S +L L+I + D G+Y C EVG C A ++EP Sbjct: 526 FKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCVATHLLKEPP 585 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 F ++ +F + T E + V W K + VI++ K + L I Sbjct: 586 -TFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTI 644 Query: 1256 RKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314 +YTC+ +A S T + +V+ P KI++ ++ G TL Sbjct: 645 PDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVSGT 704 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P+ +W + + + K + S + A L E D+G Y + N G + E Sbjct: 705 PELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETT 764 Query: 1375 VTILDKPSPP--GKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVK 1431 T+LD+ P KP + +DS C + + G+ + + + + +E+ ++ + Sbjct: 765 FTVLDRDIAPLFTKP-LRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIA 823 Query: 1432 NITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 + T + I + N + F A N V D+S +++E V KP Sbjct: 824 FVEGTASLEISRVDMNDAGNFTCRATNSVGSKDSSGAL----IVQEPP---SFVTKPGSR 876 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXX 1546 P + L F G + W++ K+L + + Y + Sbjct: 877 DVL-PGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSG 935 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 Y C N G VE S + +++ P I + Q K GD + + G PP ++ W Sbjct: 936 TYTCKVSNVAGSVECSADLFVKE-PATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITW 994 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + N +L ++ ++ E T+V+R+ ++ S +Y EA N AG+ + V + P Sbjct: 995 FANDRELRESSKHKMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKESP 1054 Score = 240 bits (587), Expect = 3e-61 Identities = 242/1077 (22%), Positives = 438/1077 (40%), Gaps = 75/1077 (6%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F KK +++ V + EC++ PE + W EI ++ E + Sbjct: 3965 PPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSV--- 4021 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ++L++ ++ G YT A N G AS LK+K EPP + + +G Sbjct: 4022 -AILEMHSLSVEDSGDYTCEARNAAGSASSSTSLKVK----EPPVFRKKPFPVETLKGAD 4076 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V L ++ G P ++W K+ + + K S+ SI IL D G Y KA Sbjct: 4077 VHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLLTSIHILNVDTA-DIGEYQCKAT 4135 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G +T++ P P F+ + +I+ ++L + S+ W++ Sbjct: 4136 NDVGSDTCVGSVTMKAP-------PQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFK 4188 Query: 869 NN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 + EI+ S+ I ++ ENI + + ++G Y C N AG A +++ +E Sbjct: 4189 DKGEIVRESDNIWISYS-ENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSV-LEP 4246 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 V+ +S + G T LEC S T +STKW+ + KE++ + +I + Sbjct: 4247 AAIVEK-PESIKVTTGDTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLK 4305 Query: 986 XXXXXXXDVGVIKCIVKD----QETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVE 1039 D GV V++ + V + I P F RKL++ ++E + Sbjct: 4306 IINVVPGDSGVYSFEVQNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECK 4365 Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094 + S V+W DG I + KY + L + D G+Y+CI + + Sbjct: 4366 VYGSPPISVLWFHDGNEISSGR-KYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSD 4424 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHI 1152 C+A +TV E PP + + V G+ TF + KG V WFK +E+ Sbjct: 4425 ECSAPLTVRE-PPSFVQKPDPMDVLTGSNVTFT-SIVKGSPPFTVSWFKGSTELVPGARC 4482 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 +++ +L+++D D +GEY+C E G + CT L V+ P+I F RL ++ + Sbjct: 4483 NVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRASCTTRLFVKAPAI-FVKRLNDYSIE 4541 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 + VTW K + +++ + + K L I T +D +Y C Sbjct: 4542 KGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNC 4601 Query: 1269 VLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + +A K + ++ ++E PP V ++ G +L P+ W Sbjct: 4602 YIENASGKDSCSAQILILE-PPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSWYKGDT 4660 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 ++ K + A+L +V+++D+G Y R EN+ G +T+ ++ PP Sbjct: 4661 KLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSF 4720 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKNITKTQTS-IQ 1441 L D E G + V E + W +K+ QTS + Sbjct: 4721 SRQLR----------DVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLD 4770 Query: 1442 NLKTNSSYRFRAYAVNEVDISDAS---ETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 N+ T + ++ + + + + K+I P + PL + E Sbjct: 4771 NIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFFDIPLAPMDAVVGES 4830 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFN 1554 +L C G KVTW +D +++++ + +Y EN Y C A N Sbjct: 4831 ADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVN 4890 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 + G+ + + I+++ + + + + + G+ + + + G P V WYKN + Sbjct: 4891 EVGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVE 4950 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + I K ++++K + + YT +A+N AG++ ++ V +P KP Sbjct: 4951 IHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSALCTSSI-VIKEPKKP 5006 Score = 238 bits (583), Expect = 1e-60 Identities = 250/1090 (22%), Positives = 447/1090 (41%), Gaps = 69/1090 (6%) Query: 633 PPTFSKKPKAQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F KK A V +G I LEC++ PE + W E+ +++ + + Sbjct: 3024 PPKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVNSV--- 3080 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ++L I G Y A N G+AS LK+K PP + + +G Sbjct: 3081 -ALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKA----PPVFTQKPPPVGALKGSD 3135 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKA 807 VIL ++ G P + W K+ K V++ T + DT S+ I + D G Y KA Sbjct: 3136 VILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDT-SLHIFN-LEAPDIGEYHCKA 3193 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G ++T A T + EPP F+ + + + ++L A V S+ W Sbjct: 3194 TNEVG-SDTCAC------TVKFKEPPRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWL 3246 Query: 868 RNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ E+I SE + +F +NI + SG Y C N AG A +T+ +E Sbjct: 3247 KDKGEVIRESENVRISFV-DNIATLQLGSPEASQSGKYVCQIKNDAGMRECSAVLTV-LE 3304 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 T V+ + T G LEC + T +S KW+ + +E+S I Sbjct: 3305 PATIVEKPEPMTVTT-GNPFTLECVVAGTPELSAKWFKDGRELSSGSRHHITFVRNLASL 3363 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI------PEFIRKLQDFEVKEKDVAILEV 1038 D G+ V+++ + V + P F+R+L+D +LE Sbjct: 3364 KIPSAEMNDKGLYTFEVENRVGKSSCTVSVHVSDRVVPPSFVRRLKDTSATLGASVVLEC 3423 Query: 1039 EIN-SETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL----- 1091 ++ S V W DG EII K + F ++ L + + D G Y+C+ Sbjct: 3424 RVSGSAPISVGWFLDGNEIISSPKCQSSFAD--NVCTLTLSSLEPSDTGAYTCVAANVAG 3481 Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 +DES +A +TV E PP + +V G TF + V+WFK E+ Sbjct: 3482 QDES-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVSGE 3539 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI 1206 ++++ +L++ + + +G+YSC + G++ CT L V+EP+ F RL + Sbjct: 3540 ACTISLEDFVTELELLEVEPGQSGDYSCLVTNDAGSASCTTHLFVKEPA-TFVKRLADTS 3598 Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + + + V+W K + + + + + K L I + T +D +Y Sbjct: 3599 VETGSPIVLEATYSGTPPISVSWMKNEYPLSQSPNCGITTTEKSSILEILESTIEDYAQY 3658 Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 C++ + + + V V+E PP ++ G +TL P+ W Sbjct: 3659 ACLIENEAGQDICEALVSVLE-PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKE 3717 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 ++ K + ASL I KV+++D G Y + EN+ G + I ++ PP Sbjct: 3718 HTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPP 3777 Query: 1385 GKPNILEIDSSSIN--ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 L+ ++ + ++ N + + + + + + + + T +Q Sbjct: 3778 SFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVAT-LQI 3836 Query: 1443 LKTNSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 L+T+ S+ ++ A N + + +S ++ E ++ KP+ ++ E Sbjct: 3837 LQTDQSHVGQYNCSASNPLGTASSSAKL----ILSEHEVPPFFDLKPV-SVDLALGESGS 3891 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 C G K+TW +D ++++ K T EN Y C A N Sbjct: 3892 FKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVAKGDAGQYTCYASNVA 3951 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G+ S +G+Q+ P I D + K + I G P +V+WYK+ +++ Sbjct: 3952 GKDSCSAQLGVQEPPRF-IKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQES 4010 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 ++ ++ ++ +++ + L S YT EA N AG++S +LKV + P + P + Sbjct: 4011 SKFRMSFEDSVAILEMHSLSVEDSGDYTCEARNAAGSASSSTSLKVKEPPVFRKKPFPVE 4070 Query: 1677 EISRESVTIE 1686 + V +E Sbjct: 4071 TLKGADVHLE 4080 Score = 238 bits (582), Expect = 1e-60 Identities = 245/1087 (22%), Positives = 441/1087 (40%), Gaps = 68/1087 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P F+K + G L+C++ ++W G+E+ + +A Sbjct: 772 IAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVEGT--- 828 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I+ V G +T A N G L ++ EPP + S V G + Sbjct: 829 -ASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQ----EPPSFVTKPGSRDVLPGSA 883 Query: 752 VILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V L + G+ TI W K +K + TK + S L K D G YT K Sbjct: 884 VCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSE--SSLELYAVKTSDSGTYTCKV 941 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITW 866 N G E SA + V+EP FI + + + +KG +L +VT P ITW Sbjct: 942 SNVAGSVECSADLFVKEPAT-------FIEKLEPSQLLKKGDGTQLACKVTGTPPIKITW 994 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + N+ + S +F L +T+V E DSG+Y C A N AG S H + I E Sbjct: 995 FANDRELRESSKHKMSFAESTAVLRLTDVAIE-DSGEYMCEAQNEAG-SDHCTGIVIVKE 1052 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRXXX 983 F K KS E + V+L + + T W+ + + SG ++ +Q+ + Sbjct: 1053 SPYFTKEF-KSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQD-QLVS 1110 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEI 1040 D G +C V ++ S+ + T+ P FI+K++ A + + Sbjct: 1111 LQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPPSFIKKIEATSSLRGGTAAFQATL 1170 Query: 1041 N-SETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--- 1095 S V W +D + I N + FE ++ LY+ V +G+Y C ++++ Sbjct: 1171 KGSLPITVTWLKDNDEITEDDNIRMTFEN--NVASLYLSGIEVKHDGKYVCQAKNDAGIQ 1228 Query: 1096 -CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQ 1153 C+A ++V E P I+ + V +G+ AT +++ + + +WFKDG E+ + Sbjct: 1229 RCSALLSVKE-PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYK 1287 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFIL 1207 +++ LKI + D+GEY+ EV G S C A + V + I +FT +L + Sbjct: 1288 ISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDS 1347 Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 + + + + + W+K I ++K L I + D YT Sbjct: 1348 IKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYT 1407 Query: 1268 CVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 C + ++ + V+ PP V+ + + G+ V L +W ++K Sbjct: 1408 CSATNKAGHSQCSGHLTVKEPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWFKDNK 1467 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + D S L + + D+G Y +L N+ G + + + + P K Sbjct: 1468 ELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQFIKK 1527 Query: 1387 PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLK 1444 P+ + + + + + E + TG I + + ++ EI + + T I N + Sbjct: 1528 PSPVLVLRNGQSTTF-ECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISNAR 1586 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTC 1503 +S + A N+ + S E K++ P + + L+ + + D+EL C Sbjct: 1587 VENSGTYVCEARNDAGTASCSI---------ELKVKEPPIFIRELEPVEVVKDSDVELEC 1637 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXX---XXXXXYKCIAFNDHGEV 1559 G +VTW ++ K++++ K T + Y+CI N+ G Sbjct: 1638 EVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSC 1697 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 S V +++ P E++ K + T + G PP + W K+ LE + Sbjct: 1698 ACSARVALKEPPSFIKKIENVTTVLKSSATFQST--VAGSPPISITWLKDDQILEENDNV 1755 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 +I+ ++ + ++++ + HS +YT +A N +G L V + E + Sbjct: 1756 HISFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPAQIIEKAKSVDVTE 1815 Query: 1680 RESVTIE 1686 ++ VT+E Sbjct: 1816 KDPVTLE 1822 Score = 231 bits (564), Expect = 2e-58 Identities = 240/1063 (22%), Positives = 431/1063 (40%), Gaps = 59/1063 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PPTF KK G + L+ + + W+ KG+E++ ++ I+ Sbjct: 584 PPTFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWM-KGQEVIKEDG---KIKMSFSNGV 639 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +VL I +V+ G YT +A N G + L +K EP ++IE + + V G+ Sbjct: 640 AVLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVK----EPAKIIERAELIQVTAGDPA 695 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK--PKKVKDEGVYTLKAENS 810 L V G P W K+ +P+ A ++I LK ++ D G YT + N Sbjct: 696 TLEYTVSGTPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNE 755 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G + TV + PLF + + G +L ++ + ++W+++ Sbjct: 756 VGSSSCETTFTVLD----RDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDG 811 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVT 929 + ++ S+ F L I+ VD D+G++ C A+NS G K S GA + E + Sbjct: 812 KELTASDRYQIAFVEGTASLEISRVDMN-DAGNFTCRATNSVGSKDSSGALIV--QEPPS 868 Query: 930 FVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 FV S + G V L+ Q S ++ KW+ KE+ I +E Sbjct: 869 FVTK-PGSRDVLPGSAVCLKSAFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELY 927 Query: 988 XXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEK-DVAILEVEIN- 1041 D G C V + E S L VKE FI KL+ ++ +K D L ++ Sbjct: 928 AVKTSDSGTYTCKVSNVAGSVECSADLFVKEPAT-FIEKLEPSQLLKKGDGTQLACKVTG 986 Query: 1042 SETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----C 1096 + + W D E+ + K+K F + + +L + ++ D GEY C ++E+ C Sbjct: 987 TPPIKITWFANDRELRESSKHKMSFAESTAVLRL--TDVAIEDSGEYMCEAQNEAGSDHC 1044 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 T + +V+ P ++ +V K E+ + WFKD + ++ + Sbjct: 1045 TG-IVIVKESPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTF 1103 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 + + L++ DAGEY C EVG+S C+A +T+ EP +F ++ + Sbjct: 1104 LQDQLVSLQVLKFVAADAGEYQCRVTNEVGSSTCSARVTLREPP-SFIKKIEATSSLRGG 1162 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 T A+ + VTW K I + + + + +L + +Y C Sbjct: 1163 TAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAK 1222 Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + + + V+ P I++ + +G TL V + + + +W + + + Sbjct: 1223 NDAGIQRCSALLSVKEPATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTL 1282 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNI 1389 K S+ + L I E D+G Y ++N+ G + + ++ +LD PP + Sbjct: 1283 GPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKL 1342 Query: 1390 LEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNS 1447 ++DS + E G+ I I + + QEI ++ T I L+ Sbjct: 1343 RKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTD 1402 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 S + A N+ S S + +KE VEKP ++ P ++L + GG Sbjct: 1403 SGTYTCSATNKAGHSQCSG----HLTVKEPPY---FVEKP-QSQDVNPGTRVQLKALVGG 1454 Query: 1508 VPQPKVTWYRDGKKLK--TAKATYENRXXXXXX--XXXXXXXXXYKCIAFNDHGEVETSC 1563 + W++D K+L A++ +++ Y C ND G + Sbjct: 1455 TAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKA 1514 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + +++ P + G + G P V WY +GN++ + ++Y I+ Sbjct: 1515 TIFVKEPPQFIKKPSPVLVLRN-GQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISF 1573 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + +I + +S Y EA N AGT+S + LKV + P Sbjct: 1574 VDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPP 1616 Score = 230 bits (563), Expect = 3e-58 Identities = 266/1189 (22%), Positives = 477/1189 (40%), Gaps = 96/1189 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F++K+ + G T F+ ++G +TW + I + +M +++ NVA+L Sbjct: 1147 PSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFEN-NVASLY 1205 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + + + G + C AKN AG + L V+ P + +++ D+ Sbjct: 1206 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIMEEAVSI-------------DVT 1252 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +G P T L+ + E W G+E+ +++ + Sbjct: 1253 QGDPAT-----------------LQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTV- 1294 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S+LKI + +K G YT N G +S + + PP + L+ M +G Sbjct: 1295 ---SILKIISTEKKDSGEYTFEVQNDVGRSSCKASINV-LDLIIPPSFTKKLRKMDSIKG 1350 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKA 807 + L V G+ +I W K+++ + A S D + + + D G YT A Sbjct: 1351 SFIDLECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSA 1410 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G ++ S +TV+ EPP F+ + Q V ++L A V +I W+ Sbjct: 1411 TNKAGHSQCSGHLTVK-------EPPYFVEKPQSQDVNPGTRVQLKALVGGTAPMTIKWF 1463 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++N+ + P + D + L + + + DSG Y C SN G +S A + + E Sbjct: 1464 KDNKELHPGAARSVWKDDTSTILELFSAKA-ADSGTYICQLSNDVGTTSSKATIFVK-EP 1521 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 F+K G++ ECQ + T + WY + EI+ + I Sbjct: 1522 PQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQ 1581 Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEI 1040 + G C ++ S L VKE P FIR+L+ E VK+ DV LE E+ Sbjct: 1582 ISNARVENSGTYVCEARNDAGTASCSIELKVKEP-PIFIRELEPVEVVKDSDVE-LECEV 1639 Query: 1041 NSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----S 1095 T +V W ++ + I+ K KY ++ + L+I D GEY CI+ +E + Sbjct: 1640 MGTTPFEVTWLKNNKEIRSGK-KYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCA 1698 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL 1154 C+A V + E PP I +++N + ATF+ + + + W KD ++ ++++ + Sbjct: 1699 CSARVALKE-PPSFIKKIENVTTVLKSSATFQSTVAGSPPISITWLKDDQILEENDNVHI 1757 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 + + L++ D +G Y+C E G +C A L V+EP+ + + Sbjct: 1758 SFEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPA-QIIEKAKSVDVTEK 1816 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-V 1269 + V L V W K I + F++ + + I+ + D +YT V Sbjct: 1817 DPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 1876 Query: 1270 LLDAKSTT---KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 D S++ L+V + PP + GS + + + +W + K Sbjct: 1877 ENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGK 1936 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 I + + SL + +E D Y ++ N G +T+ + PS K Sbjct: 1937 EISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSFLVK 1996 Query: 1387 PNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---TKTQTSIQN 1442 P + I S++ + G + +++ + D E +S + TS N Sbjct: 1997 PERQQAIPDSTVEF---KAVLKGTPP---FKIKWLK-DDVELVSGPKCFIGLEGSTSFLN 2049 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 L + S + Y + + T V + K V+K + + + L Sbjct: 2050 LYSVDSSKTGQYTCQVTNDVGSDSCTTMLLVTEPPKF----VKKLEASKIIKAGDSARLE 2105 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 C G P+ +V WYR+ +L TA Y ++ + C A N G Sbjct: 2106 CKITGSPEIQVVWYRNEHEL-TASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNPAG 2164 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 S V +++ PV + S I + K E + + G PP EV+WYK+ +L + K Sbjct: 2165 STSCSTKVIVKEPPVFS-SFPPIVETLK-NTEVSLECELSGTPPFEVVWYKDKRQLRSSK 2222 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +Y + +K + I I ++ + +Y +A N G+ + +K+ + P Sbjct: 2223 KYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKEPP 2271 Score = 229 bits (559), Expect = 8e-58 Identities = 243/1085 (22%), Positives = 438/1085 (40%), Gaps = 78/1085 (7%) Query: 626 ADILEGIPPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 AD+ P TF +K + +Q + +G L C++ P I W E+ ++ Sbjct: 952 ADLFVKEPATFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHKMSF 1011 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 +VL++T+V G Y A N G ++ +K E P + KS+ Sbjct: 1012 AEST----AVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVK----ESPYFTKEFKSI 1063 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEG 801 V + V+L A+V G P ITW K+N +++ T S+ +LK D G Sbjct: 1064 EVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLK-FVAADAG 1122 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y + N G + SA +T+ EP P FI + + + GT A + + Sbjct: 1123 EYQCRVTNEVGSSTCSARVTLREP-------PSFIKKIEATSSLRGGTAAFQATLKGSLP 1175 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 ++TW ++N+ I+ + I F+ L ++ ++ + D G Y C A N AG A + Sbjct: 1176 ITVTWLKDNDEITEDDNIRMTFENNVASLYLSGIEVKHD-GKYVCQAKNDAGIQRCSALL 1234 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDHR----- 973 ++ E T ++ S + +G L+ + S T +S KW+ + +E++ G ++ Sbjct: 1235 SVK-EPATIMEEAV-SIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTD 1292 Query: 974 -----EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE- 1027 +II + DVG C K L++ P F +KL+ + Sbjct: 1293 TVSILKIISTEKKDSGEYTFEVQNDVGRSSC--KASINVLDLIIP---PSFTKKLRKMDS 1347 Query: 1028 VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 +K + + + S + W +D + I +K+ F + L I D G Y Sbjct: 1348 IKGSFIDLECIVAGSHPISIQWFKDDQEISAS-DKHKFSFHDNTAFLEISQLEGTDSGTY 1406 Query: 1088 SCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFK 1141 +C +++ C+ +TV E PP + + Q+Q VN G + + L G A ++WFK Sbjct: 1407 TCSATNKAGHSQCSGHLTVKE-PPYFVEKPQSQDVNPGTRVQLKA-LVGGTAPMTIKWFK 1464 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSIN 1197 D E+ + D L+++ D+G Y C+ VG + A + V+EP Sbjct: 1465 DNKELHPGAARSVWKDDTSTILELFSAKAADSGTYICQLSNDVGTTSSKATIFVKEPPQF 1524 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 P +L + + + V+WY + I D K+ + T I Sbjct: 1525 IKKPSPVLVLRNGQSTTFECQVTGTPEIRVSWYLDGNEITDLRKYGISFVDGLATFQISN 1584 Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ 1316 ++ Y C + T +E+ V+ PP + + + SDV L + Sbjct: 1585 ARVENSGTYVCEARNDAGTASCSIELKVKEPPIFIRELEPVEVVKDSDVELECEVMGTTP 1644 Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 W+ N+K I+ K S L I K + +D G Y+ + N G V Sbjct: 1645 FEVTWLKNNKEIRSGKKYTMSEKMSVFYLHITKCDPSDVGEYQCIIANEGGSCACSARVA 1704 Query: 1377 ILDKPSPPGK-PNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNIT 1434 + + PS K N+ + SS + G+ I I ++ + Q ++ + + + Sbjct: 1705 LKEPPSFIKKIENVTTVLKSSATF---QSTVAGSPPISITWLKDDQILEENDNVHISFED 1761 Query: 1435 KTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 T ++++ S R+ A NE I E + +++E + +EK K++ Sbjct: 1762 SVATLQVRSVDNGHSGRYTCQAKNESGI----ERCYAFLLVQEP---AQIIEKA-KSVDV 1813 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXXXXXXXXX-YK 1549 + + L C+ G P+ KV W +DGK++ ++ ++EN Y Sbjct: 1814 TEKDPVTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYT 1873 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYK 1608 ND G + + + + + + + KV G + + G P W+K Sbjct: 1874 FKVENDFGSSSCDAYLRVLDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFK 1933 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS- 1667 +G ++ +Y + E T + + L+ ++ YT + SN AG ++ L V + PS Sbjct: 1934 DGKEISTSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPSF 1993 Query: 1668 --KPE 1670 KPE Sbjct: 1994 LVKPE 1998 Score = 227 bits (554), Expect = 3e-57 Identities = 245/1135 (21%), Positives = 455/1135 (40%), Gaps = 68/1135 (5%) Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXX 625 +L +R + +D T + F T L I ++D G+ T Sbjct: 800 SLPMRVSWFKDGKELTASDRYQIAFVEGTASLEISRVDMNDAGN-FTCRATNSVGSKDSS 858 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAI 684 ++ PP+F KP ++ V GS + L+ I W FKG+ E+V + + Sbjct: 859 GALIVQEPPSFVTKPGSRDVLPGSAVCLKSAFQGSAPLTIKW-FKGDKELVSGGSCYITK 917 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-S 743 E+ S L++ VK GTYT N G L + KEP IE L+ S Sbjct: 918 ETSE----SSLELYAVKTSDSGTYTCKVSNVAGSVECSADLFV----KEPATFIEKLEPS 969 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEG 801 ++++G+ L+ +V G P ITW N++ ++ + S ++ ++ L ++D G Sbjct: 970 QLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKHKMSFAESTAVLRLTDVAIEDSG 1029 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y +A+N G + ++ V+ E P F F+ I V ++ + L+A V P Sbjct: 1030 EYMCEAQNEAGSDHCTGIVIVK-------ESPYFTKEFKSIEVLKEYDVMLLAEVAGTPP 1082 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 ITW+++N + + + L + + D+G+Y+C +N G S+ ARV Sbjct: 1083 FEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVA-ADAGEYQCRVTNEVGSSTCSARV 1141 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKWYHNKKEISGMDHREIIQEGR 980 T+ E +F+K ++ + G + S ++ W + EI+ D+ + E Sbjct: 1142 TLR-EPPSFIKKIEATSSLRGGTAAFQATLKGSLPITVTWLKDNDEITEDDNIRMTFENN 1200 Query: 981 XXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAIL 1036 G C K+ Q S +L VKE + + +V + D A L Sbjct: 1201 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP-ATIMEEAVSIDVTQGDPATL 1259 Query: 1037 EVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094 +V+ + ++ W +DG+ + KY + L I +T D GEY+ ++++ Sbjct: 1260 QVKFSGTKEISAKWFKDGQEL-TLGPKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDV 1318 Query: 1095 ---SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQF 1148 SC A + V++L PP +L+ KG+ E + + ++WFKD EI Sbjct: 1319 GRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISA 1378 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204 S+ + + L+I + D+G Y+C + G+S+C+ LTV+EP + + P+ Sbjct: 1379 SDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHSQCSGHLTVKEPP--YFVEKPQ 1436 Query: 1205 FILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 V T L + + + W+K + ++ D L + D Sbjct: 1437 SQDVNPGTRVQLKALVGGTAPMTIKWFKDNKELHPGAARSVWKDDTSTILELFSAKAADS 1496 Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEW 1321 Y C L + TT K + V+ PP+ + + R G T P+ W Sbjct: 1497 GTYICQLSNDVGTTSSKATIFVKEPPQFIKKPSPVLVLRNGQSTTFECQVTGTPEIRVSW 1556 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 ++ I + S A+ I ++G Y N+ G A + + + + P Sbjct: 1557 YLDGNEITDLRKYGISFVDGLATFQISNARVENSGTYVCEARNDAGTASCSIELKVKEPP 1616 Query: 1382 SPPGKPNILE-IDSSSINICWDEPENTGNSTI-IYYVVEYQEIDT-TEWISVKNITKTQT 1438 + +E + S + + E E G + + ++ +EI + ++ + ++ Sbjct: 1617 IFIRELEPVEVVKDSDVEL---ECEVMGTTPFEVTWLKNNKEIRSGKKYTMSEKMSVFYL 1673 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 I + ++ NE S +KE P+ K ++N+TT Sbjct: 1674 HITKCDPSDVGEYQCIIANEGGSCACSARV----ALKE----PPSFIKKIENVTTVLKSS 1725 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK---TAKATYENR-XXXXXXXXXXXXXXXYKCIAFN 1554 G P +TW +D + L+ ++E+ Y C A N Sbjct: 1726 ATFQSTVAGSPPISITWLKDDQILEENDNVHISFEDSVATLQVRSVDNGHSGRYTCQAKN 1785 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + G + +Q+ I + + K D + V+ G P +V W K+G ++ Sbjct: 1786 ESGIERCYAFLLVQEPAQIIEKAKSVDVTEK--DPVTLECVVAGTPELKVKWLKDGKQIV 1843 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + ++++ + + RI+ + + S +YT + N G+SS + L+V D+ P Sbjct: 1844 PSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQDIPP 1898 Score = 221 bits (541), Expect = 1e-55 Identities = 250/1121 (22%), Positives = 443/1121 (39%), Gaps = 63/1121 (5%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 F S L V + + H T A +L P +K K+ V E Sbjct: 1759 FEDSVATLQVRSVDNGHSGRYTCQAKNESGIERCYAFLLVQEPAQIIEKAKSVDVTEKDP 1818 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + LEC + PE + WL G++IVP S++ E+++ + +I +V K G YT Sbjct: 1819 VTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASF----RIQSVMKQDSGQYTF 1874 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 N G +S L++ + PP + L M G S+ + +V G+ + W K Sbjct: 1875 KVENDFGSSSCDAYLRV-LDQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFK 1933 Query: 771 NNKPVKALPTKSDGDTHSITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 + K + + K H T+ + +++D YT K N G S ++TV+ Sbjct: 1934 DGKEI-STSAKYRLVCHENTVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVK---- 1988 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886 EPP F+ + + T++ A + P I W +++ E++S + +G Sbjct: 1989 ---EPPSFLVKPERQQAIPDSTVEFKAVLKGTPPFKIKWLKDDVELVSGPKCFI-GLEGS 2044 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 L + +VDS +G Y C +N G S + + E FVK L+ S + G + Sbjct: 2045 TSFLNLYSVDSS-KTGQYTCQVTNDVGSDSCTTMLLV-TEPPKFVKKLEASKIIKAGDSA 2102 Query: 947 ILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD- 1003 LEC+ S + WY N+ E++ D ++ D G C ++ Sbjct: 2103 RLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSVAVIQMNSLGTEDSGDFICEAQNP 2162 Query: 1004 ---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPK 1059 ST ++VKE P F E + LE E++ + +VVW +D ++ Sbjct: 2163 AGSTSCSTKVIVKEP-PVFSSFPPIVETLKNTEVSLECELSGTPPFEVVWYKDKRQLRSS 2221 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQN 1115 K KY + ++I N D GEY C ++E +C V + E PP+ I++L + Sbjct: 2222 K-KYKVASKNFHASIHILNVESTDIGEYHCKAQNEVGSDACVCAVKLKE-PPKFISKLNS 2279 Query: 1116 QKVNKGNKATFEIELTKGDAL-VRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 V G A + + + V+W K+ E I+ S +I+++ L+ + +A Sbjct: 2280 LTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVNNVATLQFAKVEPANA 2339 Query: 1174 GEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 G+Y C+V N + A LTV EP++ + + T A L V W Sbjct: 2340 GKYICQVKNDGGVRENMATLTVLEPAV-IIEKAGSMTVTVGETCALECKVAGTPELSVEW 2398 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE-- 1285 YK ++ ++K K +L I ++D YT + + KS+ V+V + Sbjct: 2399 YKDGKLLTSSQKHKFSFYNKISSLKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRM 2458 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSAS 1344 PP ++ G+ L + W +KI+ K+ + + + Sbjct: 2459 VPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKY-QTTFSDNVCT 2517 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 L + ++++D G Y N G + +T+ + PS +P LE+ NI + Sbjct: 2518 LQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPSFVKEPEPLEVLPGK-NITFTSV 2576 Query: 1405 -ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 T + ++ + + T + + N+ + S + N + Sbjct: 2577 IRGTPPFKVGWFRGARELVKGNRCNIYFEDTVAELELFNIDISQSGEYTCVVSN--NAGQ 2634 Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 AS TT + +KE T K L + + EP + I L + G VTW +DG + Sbjct: 2635 ASCTTRLF--VKE----PATFVKKLSDHSVEPGKSIILEGTYTGTLPISVTWKKDGVSIT 2688 Query: 1524 TAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 ++ T E Y C N+ G +V + P E Sbjct: 2689 PSERCNIVTTEKTCILEILSSTKGDAGHYSCEIENEAGRDACDALVSTLEPPYFVTELEP 2748 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 ++ VGD + + G P V W+K KL + EY + + ++ + Sbjct: 2749 LEA--SVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYFTNNVATLVFNKVSIND 2806 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 S +YT A N+ GT++ + ++ ++ P +++I + Sbjct: 2807 SGEYTCMAENSIGTAASKTIFRIQERQLPPSFARQLKDIEQ 2847 Score = 221 bits (539), Expect = 2e-55 Identities = 286/1305 (21%), Positives = 502/1305 (38%), Gaps = 82/1305 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F + + G I L+C++ PE I+W + ++ + ++++ Sbjct: 3680 PPYFIEPLEHVEAAIGEPITLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNV---- 3735 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L I V G YT A N G + VL IK K PP LK + G V Sbjct: 3736 ASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKE-RKLPPSFARKLKDVHETLGFPV 3794 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLKAENS 810 ++ G+ ++W K+ + +K H + L+ + G Y A N Sbjct: 3795 AFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHVATLQILQTDQSHVGQYNCSASNP 3854 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G A +SA + + E + PP F + ++ + E G+ K VT ITW + Sbjct: 3855 LGTASSSAKLILSE----HEVPPFFDLKPVSVDLALGESGSFK--CHVTGTAPIKITWAK 3908 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 +N I P L + V ++ D+G Y C ASN AGK S A++ + E Sbjct: 3909 DNREIRPGGNYKMTLVENTATLTVLKV-AKGDAGQYTCYASNVAGKDSCSAQLGVQ-EPP 3966 Query: 929 TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 F+K L +S ++ + EC+ S + WY ++ EI + E Sbjct: 3967 RFIKKLDQSRIVKQDEYTRYECKIGGSPEIKVLWYKDEVEIQESSKFRMSFEDSVAILEM 4026 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C ++ +ST L VKE P F +K E + LE E+ Sbjct: 4027 HSLSVEDSGDYTCEARNAAGSASSSTSLKVKEP-PVFRKKPFPVETLKGADVHLECELQG 4085 Query: 1043 ETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCT 1097 V W +D ++ K KY + ++I N D GEY C ++ +C Sbjct: 4086 TPPFQVSWHKDKRELRSGK-KYKIMSENLLTSIHILNVDTADIGEYQCKATNDVGSDTCV 4144 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEI-QFSNHIQLT 1155 VT+ + PP+ + +L + G + + + + + V WFKD EI + S++I ++ Sbjct: 4145 GSVTM-KAPPQFVKKLTDISTIIGKEVQLQTTIEGAEPISVAWFKDKGEIVRESDNIWIS 4203 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPAN 1211 L+ + +AG+Y+C++ N +C A L+V EP+ + PE I V Sbjct: 4204 YSENIATLQFSRAEPANAGKYTCQIKNDAGMQECYATLSVLEPAA--IVEKPESIKVTTG 4261 Query: 1212 TDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 L + L W+K + K+ + K L I D Y+ + Sbjct: 4262 DTCTLECTVSGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVVPGDSGVYSFEV 4321 Query: 1271 LD--AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + K + K+ ++V + PP +E GS V + P + W + Sbjct: 4322 QNPVGKDSCKVSIQVSDRIIPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGN 4381 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 I + + ++ + +LT+ +E DAG Y N G + +T+ + PS K Sbjct: 4382 EISSGRKYQTTLTDNTCALTVNMLEEADAGDYTCIATNVAGSDECSAPLTVREPPSFVQK 4441 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 P+ +++ + S + + T+ ++ + + + + + ++ T+ Sbjct: 4442 PDPMDVLTGSNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTS 4501 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIF 1505 S + NE AS TT + +++P + K L + + E + + L F Sbjct: 4502 QSGEYTCIVSNEA--GRASCTTRLF-------VKAPAIFVKRLNDYSIEKGKPLILEGTF 4552 Query: 1506 GGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P VTW ++G + ++ T E Y C N G+ Sbjct: 4553 SGTPPISVTWKKNGINVIASQRCNITTTEKSAILEILSSTVEDSGQYNCYIENASGKDSC 4612 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 S + I + P E +K VGD + + G P V WYK KL + Sbjct: 4613 SAQILILEPPYFVKQLEPVKVT--VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKM 4670 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 K + + ++ S S +Y A N+ G S L V ++ P +R++ +E Sbjct: 4671 HFKNNVATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDV-QE 4729 Query: 1682 SVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 +V + G E ++ Y K D+ I+ + +D ++ T I K + + Sbjct: 4730 TVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPN-IQTSFLD-NIATLNIFKTDRSLSGQ 4787 Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 + A NP+G A +++ + P + ES + G P Sbjct: 4788 YSCTATNPIG--SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADL---ECHVTGTQP 4842 Query: 1799 I-IDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 I + + + ++ G ++ I K+ + Q+ YA NE+G + Sbjct: 4843 IKVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKD---SCTA 4899 Query: 1856 KITIGKTLTPPSQPRNF--VVSESTSRSVTLKWTEPESNGGSPIT 1898 ++ I + L PPS + V E+ S L E G PIT Sbjct: 4900 QLNIKERLIPPSFTKKLSETVEETEGNSFKL---EGRVAGSQPIT 4941 Score = 215 bits (526), Expect = 8e-54 Identities = 237/1074 (22%), Positives = 416/1074 (38%), Gaps = 65/1074 (6%) Query: 633 PPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F KK +A + + G LEC++ PE + W E+ + + + Sbjct: 2083 PPKFVKKLEASKIIKAGDSARLECKITGSPEIQVVWYRNEHELTASDKYQMTFIDSV--- 2139 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +V+++ ++ G + A N G S +++K P ++E LK+ Sbjct: 2140 -AVIQMNSLGTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNT----- 2193 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 V L ++ G P + W K+ + + K S SI IL + D G Y K Sbjct: 2194 -EVSLECELSGTPPFEVVWYKDKRQLRSSKKYKVASKNFHASIHILNVEST-DIGEYHCK 2251 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A+N G + ++EP P FI++ +TV +L A + S+ W Sbjct: 2252 AQNEVGSDACVCAVKLKEP-------PKFISKLNSLTVVAGEPAELQASIEGAQPISVQW 2304 Query: 867 YRNNE-IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 + E +I SE I +F L V+ ++G Y C N G + A +T+ + Sbjct: 2305 LKEKEEVIRESENIRISFVNNVATLQFAKVEPA-NAGKYICQVKNDGGVRENMATLTV-L 2362 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983 E ++ S G+T LEC+ + T +S +WY + K ++ + + Sbjct: 2363 EPAVIIEKAG-SMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISS 2421 Query: 984 XXXXXXXXXDVGVIKCIVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAILE 1037 D G V++ ++S VV + P F R+L+D ILE Sbjct: 2422 LKILSVEKEDAGTYTFQVQNNVGKSSCTAVVDVSDRMVPPSFTRRLKDTGGVLGTSCILE 2481 Query: 1038 VEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093 ++ S + W + I KY ++ L + + D G Y+C+ + Sbjct: 2482 CKVAGSSPISIAWFHEKTKIVSGA-KYQTTFSDNVCTLQLNSLDSSDMGSYTCVAANVAG 2540 Query: 1094 -ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151 + C A +TV E PP + + +V G TF + V WF+ E+ N Sbjct: 2541 SDECRALLTVQE-PPSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNR 2599 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFIL 1207 + + +L++++ D+ +GEY+C V N+ CT L V+EP+ F +L + + Sbjct: 2600 CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA-TFVKKLSDHSV 2658 Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 P + + VTW K I +E+ +++ K L I T+ D Y+ Sbjct: 2659 EPGKSIILEGTYTGTLPISVTWKKDGVSITPSERCNIVTTEKTCILEILSSTKGDAGHYS 2718 Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 C + + + V +E PP V G V+L P+ W Sbjct: 2719 CEIENEAGRDACDALVSTLE-PPYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGD 2777 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 ++ + + A+L KV D+G Y EN+ G A + I ++ PP Sbjct: 2778 TKLRSTPEYRTYFTNNVATLVFNKVSINDSGEYTCMAENSIGTAASKTIFRIQERQLPPS 2837 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE---IDTTEWISVKNITKTQTSIQN 1442 L+ ++ + S I V Y++ + E + + + T ++ Sbjct: 2838 FARQLKDIEQTVGLPVTLTCRLNGSAPIQ-VCWYRDGVLLRDDENLQMSFVDNVAT-LKI 2895 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 L+T+ S+ + + AS T +E K +SP + +I E + Sbjct: 2896 LQTDLSHSGQYSCSASNPLGTASSTARL--TAREPK-KSPFFDIKPVSIDVIAGESADFE 2952 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 C G +VTW +D K+++ N Y C A ND G+ Sbjct: 2953 CHVTGAQPMRVTWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 3012 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 S + +++ P I D + K G+ + I G P +V+W++N ++L + Sbjct: 3013 DMCSAQLSVKEPPKF-IKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWK 3071 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 YN++ +++ I E + Y EA N G +S LKV P + P Sbjct: 3072 YNMSFVNSVALLTINEASAEDTGDYICEAHNGVGDASCSTALKVKAPPVFTQKP 3125 Score = 209 bits (511), Expect = 6e-52 Identities = 235/1069 (21%), Positives = 419/1069 (39%), Gaps = 60/1069 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F KKP +G+D+ LEC L P ++W E+ + + E+ + Sbjct: 4059 PPVFRKKPFPVETLKGADVHLECELQGTPPFQVSWHKDKRELRSGKKYKIMSENLL---- 4114 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + + I NV G Y A N G + + +K PPQ ++ L + G+ V Sbjct: 4115 TSIHILNVDTADIGEYQCKATNDVGSDTCVGSVTMKA----PPQFVKKLTDISTIIGKEV 4170 Query: 753 ILSAQVVGNPRPTITWCKNN-KPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809 L + G ++ W K+ + V+ + +I L+ + + + G YT + +N Sbjct: 4171 QLQTTIEGAEPISVAWFKDKGEIVRESDNIWISYSENIATLQFSRAEPANAGKYTCQIKN 4230 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G+ E A ++V EP + + + I V T L V+ P S W+++ Sbjct: 4231 DAGMQECYATLSV-------LEPAAIVEKPESIKVTTGDTCTLECTVSGTPELSTKWFKD 4283 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKV 928 + ++ +F + L I NV DSG Y N GK S +V+I V +++ Sbjct: 4284 GKELTSDNKYKISFFNKVSGLKIINVVPG-DSGVYSFEVQNPVGKDS--CKVSIQVSDRI 4340 Query: 929 TFVKHLQKSYETE--EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 +K ET G +V++EC+ S +S W+H+ EIS + Sbjct: 4341 IPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNTCAL 4400 Query: 985 XXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVE 1039 D G CI + E S L V+E P F++K +V +V + Sbjct: 4401 TVNMLEEADAGDYTCIATNVAGSDECSAPLTVREP-PSFVQKPDPMDVLTGSNVTFTSIV 4459 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 S V W + + P + + + + +L + + GEY+CI+ +E+ A Sbjct: 4460 KGSPPFTVSWFKGSTELVPGA-RCNVSLQDSVGELELFDVDTSQSGEYTCIVSNEAGRAS 4518 Query: 1100 VTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 T V+ P + RL + + KG E + + V W K+G + S +T Sbjct: 4519 CTTRLFVKAPAIFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWKKNGINVIASQRCNIT 4578 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 K L+I ++D+G+Y+C + G C+A + + EP F +L E + V Sbjct: 4579 TTEKSAILEILSSTVEDSGQYNCYIENASGKDSCSAQILILEPPY-FVKQL-EPVKVTVG 4636 Query: 1212 TDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-- 1268 A L ++ + V+WYK + + T + TL+ + D EY C Sbjct: 4637 DSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVATLVFTQVDSSDSGEYICRA 4696 Query: 1269 --VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + + S+T L V+ + PP R+ + G V + W + K Sbjct: 4697 ENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGK 4756 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 +K + + S A+L I K + + +G Y N G A + + + +PP Sbjct: 4757 PLKDSPNIQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLILTEGKNPPFF 4816 Query: 1387 PNILEIDSSSINICWD-EPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKT-QTSIQNL 1443 L + + D E TG I + + + +EI + + + + +I + Sbjct: 4817 DIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSGGNYQISYLENSAHLTIVKV 4876 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 S ++ YAVNEV + IKE I +K + + +L Sbjct: 4877 DKGDSGQYTCYAVNEVGKDSCTAQLN----IKERLIPPSFTKKLSETVEETEGNSFKLEG 4932 Query: 1504 IFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEV 1559 G V WY++ ++ + ++N Y C A ND G Sbjct: 4933 RVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMADAGLYTCKATNDAGSA 4992 Query: 1560 E-TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 TS +V + K GD ++ ++G P + W K G +++ Sbjct: 4993 LCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPSDR 5052 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + + T+++ +KE ++ S Y +ASN AG+ + + + + +KP+ Sbjct: 5053 CSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPA 5101 Score = 199 bits (485), Expect = 8e-49 Identities = 196/784 (25%), Positives = 321/784 (40%), Gaps = 56/784 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 IPP+F++K K GS +++EC++ P + W G EI + + Sbjct: 4341 IPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVLWFHDGNEISSGRKYQTTLTDNT--- 4397 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 C+ L + +++ G YT +A N G E S P+ + +EPP ++ M V G Sbjct: 4398 CA-LTVNMLEEADAGDYTCIATNVAGSDECSAPLTV------REPPSFVQKPDPMDVLTG 4450 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +V ++ V G+P T++W K + + A S D+ L G YT Sbjct: 4451 SNVTFTSIVKGSPPFTVSWFKGSTELVPGARCNVSLQDSVGELELFDVDTSQSGEYTCIV 4510 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G A + + V+ P +F+ R + ++++ + L + P S+TW Sbjct: 4511 SNEAGRASCTTRLFVKAPA-------IFVKRLNDYSIEKGKPLILEGTFSGTPPISVTWK 4563 Query: 868 RN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 +N N I S IT +E++ + V+ DSG Y C N++GK S A++ I + Sbjct: 4564 KNGINVIASQRCNITTTEKSAILEILSSTVE---DSGQYNCYIENASGKDSCSAQILI-L 4619 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983 E FVK L+ + G + L+CQ + T + WY ++ ++ + Sbjct: 4620 EPPYFVKQLE-PVKVTVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTATCKMHFKNNVAT 4678 Query: 984 XXXXXXXXXDVGVIKC----IVKDQETSTMLVVKE--TIPEFIRKLQDFEVKEKDVAILE 1037 D G C V + +ST L V+E P F R+L+D + + E Sbjct: 4679 LVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFE 4738 Query: 1038 VEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LR 1092 ++ SE V W +DG+ +K N +I L I T G+YSC + Sbjct: 4739 CAVSGSEPISVSWYKDGKPLKDSPN-IQTSFLDNIATLNIFKTDRSLSGQYSCTATNPIG 4797 Query: 1093 DESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFS 1149 S A++ + E PP L G A E +T + V W KD EI+ Sbjct: 4798 SASSGAKLILTEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPIKVTWAKDNREIRSG 4857 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI--NFTLRLP 1203 + Q++ L I D D+G+Y+C EVG CTA L ++E I +FT +L Sbjct: 4858 GNYQISYLENSAHLTIVKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKKLS 4917 Query: 1204 EFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 E + L + + + V WYK I T ++ L +++ + D Sbjct: 4918 ETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNNALLLQVKRASMAD 4977 Query: 1263 QCEYTC-VLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 YTC DA S T+ + ++ + PP + G V L Q Sbjct: 4978 AGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIR 5037 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 +W+ + +K S S +A L +K+ D+G Y + N G + VTI Sbjct: 5038 IQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIK 5097 Query: 1379 DKPS 1382 +KP+ Sbjct: 5098 EKPA 5101 Score = 195 bits (476), Expect = 1e-47 Identities = 218/1100 (19%), Positives = 413/1100 (37%), Gaps = 60/1100 (5%) Query: 602 APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECRLVAI 660 A L D G+ T A + PP+F KK Y+ G L C+L Sbjct: 367 AKLKDSGT-YTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPGESARLHCKLKGS 425 Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P + W +E+ + ++ + ++L IT+VK GTY+ A N G S Sbjct: 426 PVIQVTWFKNNKELSESNTVRMSFVNSE----AILDITDVKVDDSGTYSCEATNDVGSDS 481 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780 + I KEPP I+ L+ + +G + +L ++ G + W K+ K +++ Sbjct: 482 CSTEVVI----KEPPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFKDKKQIRSSKK 537 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ 840 + L+ V + + + + V T EPP F+ + Sbjct: 538 YRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCV-----ATHLLKEPPTFVKKVD 592 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 + T T+ L A V + S+ W + E+I I +F L I +V + Sbjct: 593 DFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIPDVQISL- 651 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VST 958 G Y C+A N AG + + + E ++ + + G LE S T + Sbjct: 652 GGKYTCLAENEAGSQTSVGELIVK-EPAKIIERAE-LIQVTAGDPATLEYTVSGTPELKP 709 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVV 1012 KWY + + + I + D G + ++ ET+ ++ Sbjct: 710 KWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 769 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHI 1071 ++ P F + L++ + L+ +I S V W +DG+ + ++Y Sbjct: 770 RDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKEL-TASDRYQIAFVEGT 828 Query: 1072 RKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 L I ++D G ++C + ++ +V+ PP +T+ ++ V G+ + Sbjct: 829 ASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSRDVLPGSAVCLKS 888 Query: 1129 ELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNS 1183 L ++WFK E+ +T + + L++Y D+G Y+C+V G+ Sbjct: 889 AFQGSAPLTIKWFKGDKELVSGGSCYITKETSESSLELYAVKTSDSGTYTCKVSNVAGSV 948 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF 1242 +C+A L V+EP+ F +L L+ L ++ + +TW+ + ++ K Sbjct: 949 ECSADLFVKEPA-TFIEKLEPSQLLKKGDGTQLACKVTGTPPIKITWFANDRELRESSKH 1007 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR 1301 + L + +D EY C +A S + +V+ P + + + Sbjct: 1008 KMSFAESTAVLRLTDVAIEDSGEYMCEAQNEAGSDHCTGIVIVKESPYFTKEFKSIEVLK 1067 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 DV LL + P W ++ ++ + K + + SL + K DAG Y+ R Sbjct: 1068 EYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQVLKFVAADAGEYQCR 1127 Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQ 1420 + N G + VT+ + PS K I S + G+ I + ++ + Sbjct: 1128 VTNEVGSSTCSARVTLREPPSFIKK--IEATSSLRGGTAAFQATLKGSLPITVTWLKDND 1185 Query: 1421 EI---DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 EI D N+ S +K + Y A N+ I S +KE Sbjct: 1186 EITEDDNIRMTFENNVASLYLSGIEVKHDGKY--VCQAKNDAGIQRCSALLS----VKE- 1238 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRX 1533 T+ + +I + L F G + W++DG++L K + + Sbjct: 1239 ---PATIMEEAVSIDVTQGDPATLQVKFSGTKEISAKWFKDGQELTLGPKYKISVTDTVS 1295 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-V 1592 Y ND G + + + + +++ + ++ + Sbjct: 1296 ILKIISTEKKDSGEYTFEVQNDVGRSSCKASINVLDLIIPPSFTKKLRKMDSIKGSFIDL 1355 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 ++ G P + W+K+ ++ ++ + + T+ + I +L+ + S YT A+N AG Sbjct: 1356 ECIVAGSHPISIQWFKDDQEISASDKHKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 1415 Query: 1653 TSSVEVTLKVYDKPSKPEGP 1672 S L V + P E P Sbjct: 1416 HSQCSGHLTVKEPPYFVEKP 1435 Score = 184 bits (447), Expect = 3e-44 Identities = 172/703 (24%), Positives = 305/703 (43%), Gaps = 52/703 (7%) Query: 632 IPPTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 IPP+F+KK + EG+ LE R+ +AW EI P N + +++ Sbjct: 4908 IPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFKNN--- 4964 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 +L++ G YT A N G A + IK K+PP + L + +G+ Sbjct: 4965 -ALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKE-PKKPPVFDQHLAPVTASEGD 5022 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAE 808 SV LS V G+ I W K + VK S +L+ K+ D G Y KA Sbjct: 5023 SVQLSCHVQGSEPIRIQWLKAGREVKPSDRCSFSFASGTAMLELKETAKADSGDYVCKAS 5082 Query: 809 NSEGIAETSAVITVEE-----PTEENAEPP---LFINRFQEITVKEKGTIKLVARVTRNP 860 N G + +T++E P + A F++ Q I V EK T +A+V +P Sbjct: 5083 NVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATFIAKVGGDP 5142 Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 +P++ W + ++ I + G+ +L I + ++ DSG Y+CVA N G+ Sbjct: 5143 IPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDT-TKTDSGLYRCVAFNKHGEIESNV 5201 Query: 920 RVTIDV----EKVT--FVKHLQKSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGM 970 + +D EK+ L+K+ ++G E V K Y + G+ Sbjct: 5202 NLQVDERKKQEKIEGDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGI 5261 Query: 971 -DHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLVV----KETIPEFIRKLQ 1024 D R ++Q ++ ++ +D++ LV + T E + ++ Sbjct: 5262 TDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTLIK 5321 Query: 1025 DFE----VKEKDVAI-LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 D E +K+ D ++++IN + W + E ++P NKY+ G L ++N Sbjct: 5322 DIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPS-NKYEISIDGDRHTLRVKNC 5380 Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRW 1139 D+G Y + +A++TV+E P LQ+ + +G T + + + W Sbjct: 5381 QPKDQGNYRLVCGPHIASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEW 5438 Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199 F++G ++ ++ ++ K KL I D +D G+Y+C+ + + +A L +E I FT Sbjct: 5439 FRNGRVLKPQGRVKTEVEHKVHKLTIADVRAEDQGQYTCKHEDLETSAELRIEAEPIQFT 5498 Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 R+ + I+V + A E+ + VTWYK + + +++K+ +D + + I T Sbjct: 5499 KRI-QNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVT 5557 Query: 1260 EDDQCEYTCVLL-----DAKSTTKLKVEVVEF-----PPKIVD 1292 DD+ Y+ + +A+ST +L + E PP I D Sbjct: 5558 PDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPD 5600 Score = 144 bits (350), Expect = 2e-32 Identities = 159/671 (23%), Positives = 268/671 (39%), Gaps = 31/671 (4%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P R+++ EV +A EI + W + G I + +K ++ L Sbjct: 117 PVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIY-ESDKCSIRSSNYVSSLE 175 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVEL-PPEIITRLQNQKVNKGNKATFEIEL 1130 I T V D GEY+C +E SCTA +TV E PP ++R + G A F + Sbjct: 176 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTV 235 Query: 1131 TKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----C 1185 + + + W KDG+ + S ++T K L++ + + D G YSC+ N C Sbjct: 236 SGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADIC 295 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244 A LT+ + +F L E + N +L ++ D + +TW K + + + + Sbjct: 296 QAELTIIDKP-HFIKEL-EAVQSAINKKIHLECQVDEDRKVTITWSKDGQKLPAGKDYKI 353 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPPKIVD-YEREYRIKRG 1302 + K +L I D YTC +A S++ V PP V + Y + G Sbjct: 354 YFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPG 413 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 L + P W N+K + + + S + A L I V+ D+G Y Sbjct: 414 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYSCEA 473 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 N+ G V I + PS +I + + E TG + ++ + ++I Sbjct: 474 TNDVGSDSCSTEVVIKEPPSFIKTLEPADIVRGANALLQCEIAGTGPFEVNWFK-DKKQI 532 Query: 1423 DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 +++ K TQ + L+ +S F + V + + A+E + V + P Sbjct: 533 RSSK----KYRLFTQKTFVYLEISS---FNSADVGDYECVVANEVGKCGCVATHLLKEPP 585 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXX- 1538 T K + + T + + L G V W + + +K K ++ N Sbjct: 586 TFVKKVDDFTALAGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVAVLTIP 645 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C+A N+ G +TS I ++P I ++ Q GD + + G Sbjct: 646 DVQISLGGKYTCLAENEAGS-QTSVGELIVKEPAKIIERAELIQV-TAGDPATLEYTVSG 703 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P + WYK+G L K+Y I+ K + ++ + S +YT E SN G+SS E Sbjct: 704 TPELKPKWYKDGRPLVASKKYRISFKNNIAQLKFYSAELHDSGQYTFEISNEVGSSSCET 763 Query: 1659 TLKVYDKPSKP 1669 T V D+ P Sbjct: 764 TFTVLDRDIAP 774 Score = 143 bits (346), Expect = 5e-32 Identities = 212/968 (21%), Positives = 373/968 (38%), Gaps = 99/968 (10%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAI 684 A IL PP F K+ + V G L+C+L PE ++W +KG+ ++ P + Sbjct: 4614 AQILILEPPYFVKQLEPVKVTVGDSASLQCQLAGTPEIGVSW-YKGDTKLRPTATCKMHF 4672 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 ++++ + L T V G Y A N GE S L ++ +K PP L+ + Sbjct: 4673 KNNV----ATLVFTQVDSSDSGEYICRAENSVGEVSSSTFLTVQE-QKLPPSFSRQLRDV 4727 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGV 802 G V+ V G+ +++W K+ KP+K P +I L K G Sbjct: 4728 QETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSFLDNIATLNIFKTDRSLSGQ 4787 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y+ A N G A + A + + E PP F + + L VT Sbjct: 4788 YSCTATNPIGSASSGAKLIL----TEGKNPPFFDIPLAPMDAVVGESADLECHVTGTQPI 4843 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +TW ++N I ++ + L I VD DSG Y C A N GK S A++ Sbjct: 4844 KVTWAKDNREIRSGGNYQISYLENSAHLTIVKVDKG-DSGQYTCYAVNEVGKDSCTAQLN 4902 Query: 923 IDVEKV--TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978 I + +F K L ++ E EG + LE + S ++ WY N EI + EI+ + Sbjct: 4903 IKERLIPPSFTKKLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNVEIHPTSNCEIMFK 4962 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTM----LVVKE--TIPEFIRKLQDFEVKEKD 1032 D G+ C + S + +V+KE P F + L E D Sbjct: 4963 NNALLLQVKRASMADAGLYTCKATNDAGSALCTSSIVIKEPKKPPVFDQHLAPVTASEGD 5022 Query: 1033 VAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-- 1089 L + SE + W + G +KP ++ F L ++ T+ D G+Y C Sbjct: 5023 SVQLSCHVQGSEPIRIQWLKAGREVKP-SDRCSFSFASGTAMLELKETAKADSGDYVCKA 5081 Query: 1090 --ILRDESCTAEVTVVELPPE--------------IITRLQNQKVNKGNKATFEIELTKG 1133 + ++ +VT+ E P ++ Q+ +V + ATF I G Sbjct: 5082 SNVAGSDTSKCKVTIKEKPAAAPAAKKAAVDGKLFFVSEPQSIRVVEKTTATF-IAKVGG 5140 Query: 1134 DAL--VRWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCT 1186 D + V+W K ++ I + G + KL+I D D+G Y C + G + Sbjct: 5141 DPIPNVKWTKGKWRQLNQGGRILIHQKGDEAKLEIRDTTKTDSGLYRCVAFNKHGEIESN 5200 Query: 1187 AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL-- 1244 L V+E + + + T A +E +D+ K ++ EK+ Sbjct: 5201 VNLQVDERKKQEKIE-GDLRAMLKKTPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMY 5259 Query: 1245 -ISDVK---KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDYEREYR 1298 I+D + + ++++ E++ L+ + + E V ++ E Sbjct: 5260 GITDFRGLLQAFELLKQSQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTL 5319 Query: 1299 IKRGSDVTLLVDYQA---------FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 IK + T+L D A +P+ W ++ ++ + SID +L +K Sbjct: 5320 IKDIENQTVLKDNDAIFEIDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKN 5379 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 + D G Y+L CG +T+++ P + ++ ++ C Sbjct: 5380 CQPKDQGNYRL----VCGPHIASAKLTVIE---PAWERHLQDVTLKEGQTC--------T 5424 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT- 1468 T + V + +EW + K Q + KT ++ + +V D + T Sbjct: 5425 MTCQFSVPNVK----SEWFRNGRVLKPQGRV---KTEVEHKVHKLTIADVRAEDQGQYTC 5477 Query: 1469 --EYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-K 1523 E + E +I++ ++ K ++NI ++ C VTWY+ +L + Sbjct: 5478 KHEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTE 5536 Query: 1524 TAKATYEN 1531 + K + N Sbjct: 5537 SQKYNFRN 5544 Score = 123 bits (297), Expect = 5e-26 Identities = 138/604 (22%), Positives = 244/604 (40%), Gaps = 46/604 (7%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E P+F + L P +G +VQ C V+G +I W + +KPS D + Sbjct: 5001 KEPKKPPVFDQHLAPVTASEGDSVQLSCHVQGSEPIRIQWLKAGREVKPS-DRCSFSFAS 5059 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXX 622 A L ++E D+G + C A N AG +S ++ I E P + ++ Sbjct: 5060 GTAMLELKETAKADSGDYVCKASNVAGSDTSKCKVTIKEKPAAAPAAKKAA--------- 5110 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENIS 681 ++G F +P++ V E + ++ P P++ W K ++ I Sbjct: 5111 ------VDG-KLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRIL 5163 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 + + D + L+I + K G Y VA N+ GE + L++ +K+ ++ L Sbjct: 5164 IHQKGDE----AKLEIRDTTKTDSGLYRCVAFNKHGEIESNVNLQVDERKKQ-EKIEGDL 5218 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKP----KK 796 ++M+ + + + KN P + + G T +L+ K+ Sbjct: 5219 RAMLKK--TPALKKGSGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQ 5276 Query: 797 VKDEGVYTLKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIK 851 ++E + L+ E E E ++ + EP I + TV K+ I Sbjct: 5277 SQEEETHRLEIEELEKSERDEKEFEELVAFIQQRLTQTEPVTLIKDIENQTVLKDNDAIF 5336 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 + P ++WY+ E + PS + DG+ L + N + D G+Y+ V Sbjct: 5337 EIDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKNCQPK-DQGNYRLVC--- 5392 Query: 912 AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGM 970 H A + V + + +HLQ +EG+T + CQ S V ++W+ N + + Sbjct: 5393 ---GPHIASAKLTVIEPAWERHLQ-DVTLKEGQTCTMTCQFSVPNVKSEWFRNGRVLKPQ 5448 Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030 + E + D G C +D ETS L ++ +F +++Q+ V E Sbjct: 5449 GRVKTEVEHKVHKLTIADVRAEDQGQYTCKHEDLETSAELRIEAEPIQFTKRIQNIVVSE 5508 Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 A E E++ + A V W + G + KY+F G + I N + DEG YS I Sbjct: 5509 HQSATFECEVSFDDAIVTWYK-GPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVI 5567 Query: 1091 LRDE 1094 R E Sbjct: 5568 ARLE 5571 Score = 107 bits (258), Expect = 3e-21 Identities = 129/599 (21%), Positives = 240/599 (40%), Gaps = 34/599 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P I R++ +V G+ A F E+ +G VR WFK G EI S+ + L+ Sbjct: 117 PVIKRRIEPLEVALGHLAKFTCEI-QGAPNVRFQWFKAGREIYESDKCSIRSSNYVSSLE 175 Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA-YLTVE 1219 I + D GEY+C E G+ CTA LTV E L P+ + A +L Sbjct: 176 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKALTTFVGKAAKFLCTV 235 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT 1277 +++ W K + + + + K +L + T D+ Y+C + Sbjct: 236 SGTPVIEIIWQKDGAALSPSPDCRVTDADNKHSLELSNLTVQDRGIYSCKASNKFGADIC 295 Query: 1278 KLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 + ++ +++ P I + E + I + + VD + W + + + K K Sbjct: 296 QAELTIIDKPHFIKELEAVQSAINKKIHLECQVDEDR--KVTITWSKDGQKLPAGKDYKI 353 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDS 1394 + K ASL I + D+G Y N G + V + + PS K P+ L + Sbjct: 354 YFEDKIASLEIPLAKLKDSGTYTCTASNEAGSSSSSAAVAVREPPSFVKKVDPSYLMLPG 413 Query: 1395 SSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFR 1452 S + + G+ I + + +E+ + + + + ++ I ++K + S + Sbjct: 414 ESARL---HCKLKGSPVIQVTWFKNNKELSESNTVRMSFVNSEAILDITDVKVDDSGTYS 470 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A N+V SD+ T VIKE P+ K L+ + L C G + Sbjct: 471 CEATNDVG-SDSCSTEV---VIKEP----PSFIKTLEPADIVRGANALLQCEIAGTGPFE 522 Query: 1513 VTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 V W++D K+++++K T + Y+C+ N+ G+ ++ Sbjct: 523 VNWFKDKKQIRSSKKYRLFTQKTFVYLEISSFNSADVGDYECVVANEVGKCGCVATHLLK 582 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 + P +D G + A + G P V+W K ++ D + ++ + Sbjct: 583 EPPTFVKKVDDFTAL--AGQTVTLQAAVRGSEPISVMWMKGQEVIKEDGKIKMSFSNGVA 640 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 V+ I +++ S KYT A N AG+ + L V + E +++ + + T+E+ Sbjct: 641 VLTIPDVQISLGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEY 699 Score = 76.6 bits (180), Expect = 7e-12 Identities = 46/120 (38%), Positives = 62/120 (51%), Gaps = 5/120 (4%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 G+ A FE ++ A+ W KDGS I+ S + DGK +KL I D L DAGEY+C Sbjct: 8126 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVL 8185 Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 +GN + TA L VEE + F L E + V YL+ E+ E DV W K ++ Sbjct: 8186 RLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIV 8244 Score = 71.3 bits (167), Expect = 3e-10 Identities = 32/87 (36%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV +L P G +V +CQV G P ++WF+ ++ + +++ Y+ +NVATLV Sbjct: 2740 PYFVTELEPLEASVGDSVSLQCQVAGTPEITVSWFKGDTKLRSTPEYRTYF-TNNVATLV 2798 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTT 596 +V D+G +TC+A+N+ G A+S T Sbjct: 2799 FNKVSINDSGEYTCMAENSIGTAASKT 2825 Score = 67.3 bits (157), Expect = 4e-09 Identities = 50/162 (30%), Positives = 82/162 (50%), Gaps = 12/162 (7%) Query: 1018 EFIRKLQDFEVKEKDV----AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 +F+++++D + E + AI E ++ TA W +DG I+ + K+ F G RK Sbjct: 8109 KFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIR-ESPKHRFIADGKDRK 8167 Query: 1074 LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEI 1128 L+I + + D GEY+C+LR +++ TA++ V ELP + L+ + V KG Sbjct: 8168 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSC 8227 Query: 1129 ELTKGDALVRWFKDGS-EIQFSNHIQLTIDGKKQKLKIYDCD 1169 EL K +V W KDG ++ I + G + L I D D Sbjct: 8228 ELNKERDVV-WRKDGKIVVEKPGRIVPGVIGLMRALTINDAD 8268 Score = 66.9 bits (156), Expect = 6e-09 Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Query: 510 PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P F++KL K G ++Q EC++ G P ++ WFR + + S + M + + +VA L Sbjct: 3025 PKFIKKLDASKVAKQGESIQLECKISGSPEIKVVWFRNDSELHESWKYNMSFVN-SVALL 3083 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I E ED G + C A N G AS +T L V+AP Sbjct: 3084 TINEASAEDTGDYICEAHNGVGDASCSTALKVKAP 3118 Score = 62.9 bits (146), Expect = 9e-08 Identities = 60/274 (21%), Positives = 108/274 (39%), Gaps = 14/274 (5%) Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 + ++I + ++WYK +E + K+ + D + TL ++ C DQ Y V Sbjct: 5338 IDIKINYPEIKLSWYKGTEKLEPSNKYEISIDGDRHTLRVKNCQPKDQGNYRLVC--GPH 5395 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 K+ V+E P + ++ +K G T+ + P EW N +++K K Sbjct: 5396 IASAKLTVIE--PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRVLKPQGRVK 5452 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDS 1394 ++ K LTI V D G Y C H D+E + + + P I I Sbjct: 5453 TEVEHKVHKLTIADVRAEDQGQY------TCKHEDLETSAELRIEAEPIQFTKRIQNIVV 5506 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSYRFRA 1453 S E E + + I+ + E+ ++ + +N + +I N+ + + Sbjct: 5507 SEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSV 5566 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 A E +A T E Y KE K++ + P Sbjct: 5567 IARLE-PRGEARSTAELYLTTKEIKLEMKPPDIP 5599 Score = 60.5 bits (140), Expect = 5e-07 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 1/100 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ + P F +L+ G V C++ G Q+ W+R +++ ++ QM + D Sbjct: 2830 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQMSF-VD 2888 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 NVATL I + +G ++C A N G ASST L P Sbjct: 2889 NVATLKILQTDLSHSGQYSCSASNPLGTASSTARLTAREP 2928 Score = 58.8 bits (136), Expect = 2e-06 Identities = 31/101 (30%), Positives = 54/101 (53%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ +AP+F + LR + G + +C++ G +++WF+ + S +Q+ + + Sbjct: 769 DRDIAPLFTKPLRNVDSVVGGACRLDCKIAGSLPMRVSWFKDGKELTASDRYQIAFVE-G 827 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 A+L I V DAG FTC A N+ G S+ LIV+ P S Sbjct: 828 TASLEISRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPS 868 Score = 58.4 bits (135), Expect = 2e-06 Identities = 34/99 (34%), Positives = 51/99 (51%), Gaps = 1/99 (1%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T +EQ + P F +LR G V FEC V G ++W++ +K S + Q + Sbjct: 4710 TVQEQKLPPSFSRQLRDVQETVGLPVVFECAVSGSEPISVSWYKDGKPLKDSPNIQTSF- 4768 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 DN+ATL I + +G ++C A N G ASS +LI+ Sbjct: 4769 LDNIATLNIFKTDRSLSGQYSCTATNPIGSASSGAKLIL 4807 Score = 57.6 bits (133), Expect = 4e-06 Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV++ P G + F + G P ++ WFR + +Y+ +D VA L Sbjct: 2554 PSFVKEPEPLEVLPGKNITFTSVIRGTPPFKVGWFRGARELVKGNRCNIYF-EDTVAELE 2612 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP------LSDHGSE 610 + + +G +TCV N AG AS TT L V+ P LSDH E Sbjct: 2613 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPATFVKKLSDHSVE 2659 Score = 54.4 bits (125), Expect = 3e-05 Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ + P F +L+ G++ EC+V G I WF + I +Q + D N Sbjct: 2456 DRMVPPSFTRRLKDTGGVLGTSCILECKVAGSSPISIAWFHEKTKIVSGAKYQTTFSD-N 2514 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 V TL + + D G++TCVA N AG L V+ P S Sbjct: 2515 VCTLQLNSLDSSDMGSYTCVAANVAGSDECRALLTVQEPPS 2555 Score = 52.8 bits (121), Expect = 1e-04 Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 3/130 (2%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQV 533 +D+ + QY +NE + K + +E+ + P F +KL +G++ + E +V Sbjct: 4876 VDKGDSGQYTCYAVNE-VGKDSCTAQLNIKERLIPPSFTKKLSETVEETEGNSFKLEGRV 4934 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G + W++ I P+ + ++ + + N L ++ DAG +TC A N AG A Sbjct: 4935 AGSQPITVAWYKNNVEIHPTSNCEIMFKN-NALLLQVKRASMADAGLYTCKATNDAGSAL 4993 Query: 594 STTELIVEAP 603 T+ ++++ P Sbjct: 4994 CTSSIVIKEP 5003 Score = 48.4 bits (110), Expect = 0.002 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 1/96 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E AP+ ++ P G +F C+++G P + WF+ I S D + Sbjct: 112 EMKAAPVIKRRIEPLEVALGHLAKFTCEIQGAPNVRFQWFKAGREIYES-DKCSIRSSNY 170 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 V++L I D G +TC A N G S T L V Sbjct: 171 VSSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 206 Score = 48.4 bits (110), Expect = 0.002 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 2/99 (2%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++ P F+ + + T G +F C V G P +I W + A + PS D ++ D DN Sbjct: 208 EAYPPTFLSRPKALTTFVGKAAKFLCTVSGTPVIEIIWQKDGAALSPSPDCRV-TDADNK 266 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 +L + + +D G ++C A N G EL I++ P Sbjct: 267 HSLELSNLTVQDRGIYSCKASNKFGADICQAELTIIDKP 305 Score = 48.4 bits (110), Expect = 0.002 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568 P FV+KL T G V+ + VEG+ + W + +I+ S++ ++ + D N+ATL Sbjct: 3212 PRFVKKLSDASTLIGDPVELQAVVEGFQPISVVWLKDKGEVIRESENVRISFVD-NIATL 3270 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + +G + C KN AG + L V P Sbjct: 3271 QLGSPEASQSGKYVCQIKNDAGMRECSAVLTVLEP 3305 Score = 48.0 bits (109), Expect = 0.003 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +Q + P F +KL GS++ EC+V G WF+ I S +++ +N Sbjct: 1893 DQDIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVC-HEN 1951 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 +L + + ED +TC N AG + + L V+ P S Sbjct: 1952 TVSLEVSNLELEDTANYTCKVSNVAGDNACSGILTVKEPPS 1992 Score = 48.0 bits (109), Expect = 0.003 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 + +EK G T EC+V G P + W++ ++ SQ + + + +++L I Sbjct: 2366 VIIEKAGSMTVTVGETCALECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLKI 2424 Query: 571 REVFPEDAGTFTCVAKNAAGFASST 595 V EDAGT+T +N G +S T Sbjct: 2425 LSVEKEDAGTYTFQVQNNVGKSSCT 2449 Score = 47.6 bits (108), Expect = 0.004 Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATL 568 P F+ KL G + + +EG + W ++ +I+ S++ ++ + + NVATL Sbjct: 2271 PKFISKLNSLTVVAGEPAELQASIEGAQPISVQWLKEKEEVIRESENIRISFVN-NVATL 2329 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613 +V P +AG + C KN G + L V P + + MTV Sbjct: 2330 QFAKVEPANAGKYICQVKNDGGVRENMATLTVLEPAVIIEKAGSMTV 2376 Score = 44.8 bits (101), Expect = 0.026 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 1/102 (0%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T+ E +P F K G + FEC V G ++TW + I+P ++ + Sbjct: 2924 TAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRVTWSKDNKEIRPGGNYTITC- 2982 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 N L I +V D+G +TC A N G + +L V+ P Sbjct: 2983 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3024 Score = 44.8 bits (101), Expect = 0.026 Identities = 42/163 (25%), Positives = 68/163 (41%), Gaps = 9/163 (5%) Query: 1196 INFTLRLPEFILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + F + + +L A + A + T TW K S I ++ K I+D K R Sbjct: 8108 LKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRK 8167 Query: 1253 LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLV 1309 L I D EYTCVL + + T+ K+ V E P + V E E + +G + L Sbjct: 8168 LHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPLYLSC 8227 Query: 1310 DYQAFPQPNDEWIVNSKI-IKKCKHTKPSIDSKSASLTIKKVE 1351 + + + W + KI ++K P + +LTI + Sbjct: 8228 ELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDAD 8268 Score = 43.2 bits (97), Expect = 0.081 Identities = 32/139 (23%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Query: 830 AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886 A P F+ ++I + E ++ + +P +IT W ++ I S DG+ Sbjct: 8105 AVPLKFVKEIKDIVLTEAESVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGK 8164 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 + +L I +V D+G+Y CV + + A++ ++ V FVK L++ +G+ + Sbjct: 8165 DRKLHIIDVQLS-DAGEYTCVLRLGNKEKTSTAKLIVEELPVRFVKTLEEEVTVVKGQPL 8223 Query: 947 ILECQTSHTVSTKWYHNKK 965 L C+ + W + K Sbjct: 8224 YLSCELNKERDVVWRKDGK 8242 Score = 42.7 bits (96), Expect = 0.11 Identities = 55/245 (22%), Positives = 92/245 (37%), Gaps = 22/245 (8%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXX 1538 P E+ L+++T + + +TC F VP K W+R+G+ LK K E++ Sbjct: 5406 PAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRVLKPQGRVKTEVEHKVHKLTI 5464 Query: 1539 XXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y C H ++ETS + I+ +P+ Q V + T E Sbjct: 5465 ADVRAEDQGQYTC----KHEDLETSAELRIEAEPIQFTKRI---QNIVVSEHQSATFECE 5517 Query: 1598 -GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI--------EAS 1648 V WYK +L ++YN + + I + Y++ EA Sbjct: 5518 VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEAR 5577 Query: 1649 NTAGTSSVEVTLKVYDKPSK-PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 +TA +K+ KP P+ V + + +V E PP + L E+ + Sbjct: 5578 STAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKK 5637 Query: 1708 PDNNR 1712 P R Sbjct: 5638 PPAKR 5642 Score = 41.9 bits (94), Expect = 0.19 Identities = 22/97 (22%), Positives = 44/97 (45%), Gaps = 1/97 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 +P F ++ + V +V G P +ITWF+ ++ + ++ + D V+ Sbjct: 1053 SPYFTKEFKSIEVLKEYDVMLLAEVAGTPPFEITWFKDNTTLRSGRKYKTFLQDQLVSLQ 1112 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 V++ V DAG + C N G ++ + + + P S Sbjct: 1113 VLKFV-AADAGEYQCRVTNEVGSSTCSARVTLREPPS 1148 Score = 41.5 bits (93), Expect = 0.25 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 168 PDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDK 215 P V++PP+ + E K+ P ++++ E P AK E+ E P + VP K Sbjct: 7692 PKVTEPPKKPVPEKKAPPAVVKKPEPPPAKVPEVPKEAPPEKKVPPKK 7739 Score = 40.7 bits (91), Expect = 0.43 Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F +K P GS V +C++ G P ++ W + ++ S+ F++ + + + + Sbjct: 3119 PVFTQKPPPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRSSKKFKITSKNFDTSLHI 3178 Query: 570 IREVFPEDAGTFTCVAKNAAG 590 P D G + C A N G Sbjct: 3179 FNLEAP-DIGEYHCKATNEVG 3198 Score = 38.3 bits (85), Expect = 2.3 Identities = 49/238 (20%), Positives = 93/238 (39%), Gaps = 20/238 (8%) Query: 170 VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNKRSK 229 V + P+ I E K L+++ E P K + VP + +P ++E + P + Sbjct: 6737 VPEVPKKPIPEEKKPTALLKKMEAPPPKAPKKREVVPVPVALPREEEEEEVPFEEVPEEE 6796 Query: 230 LTP---IKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRI 286 + P + E + P E V + E + ++K ++ Sbjct: 6797 ILPEEEVPSEEEAPPEEVPPEEEEVLPEEEEVLPEEEEVLPEEEEVQPEEEALPEIKPKV 6856 Query: 287 KYITSWPPESIK-PLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTEL---- 341 P K P + K+ ++ + + KV+++ +PPK +V E+ Sbjct: 6857 PKPAPVPEIKKKVPEKKVVVPKKEEAPPTKVPEVSKKVEERRIIPPKEEEVPPAEVYEEA 6916 Query: 342 ----------EQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSA 389 E P E+IVE +++E E++ + E+ K+ VPE T P+K+ A Sbjct: 6917 EEPTPEEIPEEPPSIEEEEIVEEEEEEEEVLPPR--APEVVKKAVPEAPTPVPKKAEA 6972 Score = 36.3 bits (80), Expect = 9.2 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 GS+ FEC V P IT W + + I+ S + D + L I +V DAG +T Sbjct: 8126 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYT 8182 Query: 583 CVAKNAAGFASSTTELIVE 601 CV + +ST +LIVE Sbjct: 8183 CVLRLGNKEKTSTAKLIVE 8201 >UniRef50_O01761 Cluster: Muscle M-line assembly protein unc-89; n=12; Caenorhabditis|Rep: Muscle M-line assembly protein unc-89 - Caenorhabditis elegans Length = 8081 Score = 266 bits (652), Expect = 5e-69 Identities = 306/1285 (23%), Positives = 533/1285 (41%), Gaps = 104/1285 (8%) Query: 460 KHLTEEKGWVPAQYLM--DENN-----YTQYLQKKL--NEKIDKLPV----FEKPTSEEQ 506 +H+ E+KG + L+ D NN YT K +E + +L + FEK T+EE Sbjct: 3625 QHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE- 3683 Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 + P+F+E L+ +G TV EC+V PQI +F+ ++ Q Q+ +D Sbjct: 3684 -VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNI 3742 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTEL------IVEAPLSDHGSEMTVXXXXXXX 620 L I+ ED G + C A N AG A++ +L VE ++D ++ Sbjct: 3743 KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESGQLEEIGQFETV 3802 Query: 621 XXXXXADILEGI-PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 + G P F + ++ V E +L+C++ P P I W +G+E+ Sbjct: 3803 GDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSAR 3862 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK---EP 734 + + D + L NV + G Y A N G A PI++ ++ K E Sbjct: 3863 VRAEHKDDGTL---TLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEGAPKIDGEA 3919 Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKS-DGDTHSIT 790 P ++P+K +V GE+ +L ++ G P+P++ W KN KP + ++ D T +T Sbjct: 3920 PDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLT 3979 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 + K+ D Y +A N G + +TV+EP + P F I VKE T Sbjct: 3980 VTN-AKLDDMDEYRCEASNEFGDVWSDVTLTVKEPAQ---VAPGFFKELSAIQVKETETA 4035 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909 K +V+ P + W+++ + + + ++ D LVI + ++ D G+Y+ S Sbjct: 4036 KFECKVS-GTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTD-DQGNYRIEVS 4093 Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS 968 N AG ++ +T+ + +K +G ++L + T KWY + ++ Sbjct: 4094 NDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKGTETVT 4153 Query: 969 GMDHREIIQEGRX-XXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKE----TIPE 1018 +I+Q D G + ++ + ++T+ V K ++P Sbjct: 4154 SSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISLPS 4213 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR-KLYIR 1077 F + L D V + +LEVEI + DV W ++G+ IK K E G+ + +L I Sbjct: 4214 FKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIKDGK----VEDLGNGKYRLTIP 4269 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134 + D GEYS +E+ E V PEI++ L V +G ATF +++ Sbjct: 4270 DFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKGPV 4329 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILT 1190 V+W+K+G EI + + DG L+I + ++DA +Y S + G++ +A LT Sbjct: 4330 KGVKWYKNGKEIPDAK-TKDNGDG-SYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALT 4387 Query: 1191 VEEPSINFTLRLPEFI--LVPANT----DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244 V+ PE + L+P A V++ V WYK I + + Sbjct: 4388 VKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAK--AK 4445 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRG 1302 + +L I DD +Y V+ DA V+ P IV + + +G Sbjct: 4446 DNGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKG 4505 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLR 1361 L V+ P+ +W N K I +P D L I + DA YK+ Sbjct: 4506 KKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564 Query: 1362 LENNCGH-ADVEMNVTILDKPSPPGKPNILE-IDSSSINICWD---EPENTGNSTIIYYV 1416 L + G+ AD +T+ P +P I++ ++ ++I E E +G+ + + Sbjct: 4565 LTDEDGNTADSSCALTV---KLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWY 4621 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E+ ++K I K + L+ SS ++A K+ E Sbjct: 4622 KNGKELPGAAAKTIK-IQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE 4680 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYEN 1531 KI T KPLK+ + E+ E + P+ V WY++G+++K + + Sbjct: 4681 PKI---TFLKPLKDQSITEGENAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDT 4736 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----ITISNEDIKQKHKVG 1587 + YK + N GE E+S + +++ I ED Q G Sbjct: 4737 KYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLED--QVVAKG 4794 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646 + + I+G P +V W ++ N + I + T+ + I + +YT+E Sbjct: 4795 AKMVFEVKIQG-EPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVE 4853 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEG 1671 N +G + + +V +KP G Sbjct: 4854 VINESGKAKSDAKGEVDEKPEIVRG 4878 Score = 248 bits (607), Expect = 1e-63 Identities = 294/1183 (24%), Positives = 489/1183 (41%), Gaps = 110/1183 (9%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ + +VEG P+ + W++ T + SQ ++ ++ L I D G + Sbjct: 4127 GTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRV 4185 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 V ST VE+ + +TV P+F K Q Sbjct: 4186 VL--------STDSFSVES-----SATVTVTKAAEKISL-----------PSFKKGLADQ 4221 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V +G+ ++LE + P+ D+ W G+EI D + D+ L I + ++ Sbjct: 4222 SVPKGTPLVLEVEIEGKPK-DVKWYKNGDEI-KDGKVE-----DLGNGKYRLTIPDFQEK 4274 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G Y+V A N GE I K K P+++ L V+QGE+ + +V G P Sbjct: 4275 DVGEYSVTAANEAGE----IESKAKVNVSAKPEIVSGLVPTTVKQGETATFNVKVKG-PV 4329 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 + W KN K + TK +GD + +V+D Y + N G A++SA +TV+ Sbjct: 4330 KGVKWYKNGKEIPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389 Query: 824 EPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 + ++ P ++ TVK+ T +V + PV + WY+N + I P+ N Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKV-KGPVKQVKWYKNGKEI-PNAKAKDN 4447 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 DG + L I N + D+ DYK V SN AG + A +T+ + + VK L+ + E + Sbjct: 4448 GDG-SYSLEIPNAQLD-DTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDA-EVPK 4504 Query: 943 GKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXDVGVIKCI 1000 GK +L+ +T+ KWY N KEI+ D + +G D K + Sbjct: 4505 GKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVV 4564 Query: 1001 VKDQETSTM-----LVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG 1053 + D++ +T L VK P+ I+ L+D V LE+E + V W ++G Sbjct: 4565 LTDEDGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNG 4624 Query: 1054 EIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCILRDESCTAEVT-VVELPPEI- 1109 + + K ++ K L I ++ V D G+Y + +E+ +A + + + P+I Sbjct: 4625 KELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVEPKIT 4684 Query: 1110 -ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTIDGKKQKLKIY 1166 + L++Q + +G A F +E +V+W+K+G EI+ ++ I+ D K Q L I Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQ-LVIK 4743 Query: 1167 DCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEI 1220 + DDA Y + G ++ +A LTV++ ++ E +V V+I Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKI 4803 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 E DV W + +VI + I D R LII D EYT +++ K+ Sbjct: 4804 QGEPEDVRWLRDANVISAGANAIIEKIDDTTYR-LIIPSADLKDAGEYTVEVINESGKAK 4862 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 + K EV E P+IV I G D V+ A P +W N + IK H + Sbjct: 4863 SDAKGEVDE-KPEIVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEA 4920 Query: 1337 S-IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395 I K L I + + D YK+ L N G D +T++ KPN+L+I Sbjct: 4921 KKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV-------KPNVLKIVDG 4973 Query: 1396 SINICWDEPENT-------GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 ++ +EP+ G +I + QE+ + K K ++ +L SS Sbjct: 4974 LKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKP-DADGFKFEEKPESGEFSLTIPSS 5032 Query: 1449 YRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVE----KPLKNITTEPNEDIELTC 1503 + A V +D E V +K K PT PLK+ E + + L C Sbjct: 5033 KKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQC 5092 Query: 1504 IFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 G P P+V W +DG L+ T + + Y+ A N+ G Sbjct: 5093 TIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGS 5152 Query: 1559 VETSCVVGIQQ------KPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGN 1611 + C V + + KP I +K + GD+ + G+P P + W+ NG Sbjct: 5153 ATSDCKVTVTEQGEQPSKPKFVI---PLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGI 5209 Query: 1612 KLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 ++ D + + + I++++ A N GT Sbjct: 5210 PIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGT 5252 Score = 246 bits (603), Expect = 4e-63 Identities = 270/1080 (25%), Positives = 457/1080 (42%), Gaps = 85/1080 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V +G+ ILL + P+ + W +KG E V + ++ Y L+I + + Sbjct: 4124 VTQGTKILLSVEVEGKPKT-VKW-YKGTETVTSSQTTKIVQVTESEY--KLEIESAEMSD 4179 Query: 705 EGTYTVV-AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 G Y VV + + S V K EK P + L V +G ++L ++ G P Sbjct: 4180 TGAYRVVLSTDSFSVESSATVTVTKAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEGKP 4239 Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + + W KN +K + G+ + + KD G Y++ A N G E+ A + V Sbjct: 4240 KD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNV 4298 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 +A+P + ++ TVK+ T +V + PV + WY+N + I ++T N Sbjct: 4299 ------SAKPEI-VSGLVPTTVKQGETATFNVKV-KGPVKGVKWYKNGKEIPDAKT-KDN 4349 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKVTFVKHLQ 935 DG + L I N E D+ DYK V SN AG + A +T+ D K V L Sbjct: 4350 GDG-SYSLEIPNAQVE-DAADYKVVVSNDAGDADSSAALTVKLADDGKDKVKPEIVSGLI 4407 Query: 936 KSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994 + ++G+T + V KWY N KEI ++ D Sbjct: 4408 PT-TVKQGETATFNVKVKGPVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEIPNAQLDDT 4464 Query: 995 GVIKCIVK----DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050 K +V D ++S L VK ++ L+D EV + A+L+VE N + ++ W Sbjct: 4465 ADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWY 4524 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVV 1103 ++G+ I P + +L I + D EY +L DE SC V + Sbjct: 4525 KNGKEITPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLP 4584 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ--FSNHIQLT-IDGKK 1160 P+II L++Q V+ G+ EIE + V+W+K+G E+ + I++ ID K Sbjct: 4585 AKEPKIIKGLEDQVVSIGSPIKLEIETSGSPKTVKWYKNGKELPGAAAKTIKIQKIDDNK 4644 Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 L+I ++D G+Y EV G++ + +TVE P I F L + + +A Sbjct: 4645 YVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITVE-PKITFLKPLKDQSITEGE-NAEF 4702 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTEDDQCEYTCVLL---- 1271 +VE + V WYK I+ +F + K L+I+ DD Y VL Sbjct: 4703 SVETNTKPRIVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAG 4762 Query: 1272 DAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 +A+S+ +L V+ + KIV + + +G+ + V Q P+ + W+ ++ +I Sbjct: 4763 EAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISA 4821 Query: 1331 CKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + ID + L I + DAG Y + + N G A + + +KP Sbjct: 4822 GANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLEN 4881 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNS 1447 +EI ++ + E + + + QEI + K I K + +I + + Sbjct: 4882 IEIPEGDDDVF--KVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDD 4939 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 ++ N D+S V+K ++ + LK++ E + +EL G Sbjct: 4940 GADYKVVLSNAAGDCDSSAALT---VVKPNVLK---IVDGLKDVDVEEPQPVELKVKVEG 4993 Query: 1508 VPQPKVTWYRDGKKLKTAKATYE-------NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 +P+ + WY++G++LK ++ Y+ + ND GEV Sbjct: 4994 IPKV-IKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVY 5052 Query: 1561 TSCVVGIQQ-KPVITISNEDIKQKHK-----VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + VV ++ K S + K GD + I G P PEVIW K+G L+ Sbjct: 5053 SGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQ 5112 Query: 1615 NDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL-KVYDKPSKPE 1670 D + + T+ +RI+ K+S +Y + A N AG TS +VT+ + ++PSKP+ Sbjct: 5113 KDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPK 5172 Score = 218 bits (533), Expect = 1e-54 Identities = 236/921 (25%), Positives = 390/921 (42%), Gaps = 76/921 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E L G+ V + G P+P +TW+ I S D DD +TL Sbjct: 2754 PDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNS-DLYTIVTDDKTSTLT 2812 Query: 570 IREVFPE-DAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXA 626 I P+ G C A+N AG S T +I S+ SE + Sbjct: 2813 INSFNPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLTEDES 2872 Query: 627 --DILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 + + P P F K K +G + EC + WL G+EI Sbjct: 2873 LREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIAR 2932 Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREG----EASLPIVLKI-KTGEKE 733 I V + + + L + NV G YT + N G EA+L ++ + K EK+ Sbjct: 2933 IRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKK 2992 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITI 791 P+ I L+ + E V+L +V+G P+P ++W +NK + +++ +S +TI Sbjct: 2993 APEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTI 3052 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGT 849 ++ +G YT AEN+EG ++T A +TV+ E P+F Q E+++ EK Sbjct: 3053 TS-SELSHQGKYTCIAENTEGTSKTEAFLTVQ------GEAPVFTKELQNKELSIGEK-- 3103 Query: 850 IKLVARVTRNPVPSITWYRNNEI------ISPSETITQNFDGENI--ELVITNVDSEIDS 901 + L V +P P + +Y +E I+ S I D N +VI+ + E D Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKE-DI 3162 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKW 960 YK +A+NS G ++ +++T VE F + L+K+ +E + + +E + + +W Sbjct: 3163 VSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT-SVKEKEEIKMEVKVGGSAPDVEW 3221 Query: 961 YHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKE 1014 + + K +S + E+ + E D G + E+S V + Sbjct: 3222 FKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ 3281 Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGH- 1070 ++ P F+R+L EVK + A L V + V W +DG+ ++ + + G Sbjct: 3282 SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSG 3341 Query: 1071 IRKLYIRNTSVHDEGEYSCILRD---ESCT-AEVTVVE--LPPEIITRLQNQKVNKGNKA 1124 + I++ + D G+Y+C + E+ T A VV+ +PPE + +L +V + Sbjct: 3342 SYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKEST 3401 Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSN-H-IQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178 T +++ + V WFKD + I N H IQ L I D D G YSC Sbjct: 3402 TLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRAR 3461 Query: 1179 -EVGNSKCTAILTVEEPSI--NFTLRL-PEFILVPANTDAYLTVEIPDETLDVTWYK--K 1232 E G + TA + SI FT +L P + D +TV I +V W+K K Sbjct: 3462 NEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTV-IGTPVPNVEWFKDDK 3520 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288 I+++ F TL I++ +D YTC +AK+T + V+ P Sbjct: 3521 PINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP 3580 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT-KPSIDSKSASLT 1346 V + Y +++G L+V + P+P +W + I +H + ++ S +L Sbjct: 3581 LFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLV 3640 Query: 1347 IKKVENTDAGIYKLRLENNCG 1367 IK N D G Y + N G Sbjct: 3641 IKDTNNADFGKYTCQATNKAG 3661 Score = 209 bits (511), Expect = 6e-52 Identities = 292/1248 (23%), Positives = 486/1248 (38%), Gaps = 138/1248 (11%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E+ AP+FV+ L+P G + +VEG P P++ WF+ I + + Sbjct: 3574 QEEIEAPLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGE 3633 Query: 564 NVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 N + TLVI++ D G +TC A N AG E + E + + E Sbjct: 3634 NGSHTLVIKDTNNADFGKYTCQATNKAG----KDETVGELKIPKYSFEKQTA-------- 3681 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 E + P F + K + EG ++LEC++ P I + + + +++ + Sbjct: 3682 -------EEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQL 3734 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 + D ++ L I N KK G Y AVN G+A+ LKI+ K V + Sbjct: 3735 EVLEDGNI---KLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKIQFAAKVEEHVTDESG 3791 Query: 743 SM-IVRQGESV-------------------ILSAQVVGNPRPTITWCK-NNKPVKALPTK 781 + + Q E+V +L + V + I CK +P + Sbjct: 3792 QLEEIGQFETVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWT 3851 Query: 782 SDGDTHSITILKPKKVKDEGVYTL---------------KAENSEGIAETSA--VITVEE 824 +G ++ + KD+G TL +AEN G A T ++T+E Sbjct: 3852 KEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAENEYGSAWTEGPIIVTLEG 3911 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNF 883 + + E P F+ + V T L +++ P PS+ WY+N E + PS+ + +N Sbjct: 3912 APKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENL 3971 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVT--FVKHLQKSYET 940 D L +TN + D +Y+C ASN G +T+ + +V F K L + + Sbjct: 3972 DDGTQRLTVTNAKLD-DMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKEL-SAIQV 4029 Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEI--SGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 +E +T EC+ S T KW+ + + H E +G D G Sbjct: 4030 KETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDG-TQRLVIEDSKTDDQGNY 4088 Query: 998 KC-IVKDQETSTMLVVKETIPEFIRK----LQDFEVKEKDVAILEVEINSETADVVWERD 1052 + + D + V +P K L D V + +L VE+ + V W + Sbjct: 4089 RIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPKTVKWYKG 4148 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP-- 1106 E + + + KL I + + D G Y +L +S + E VTV + Sbjct: 4149 TETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEK 4208 Query: 1107 ---PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 P L +Q V KG E+E+ V+W+K+G EI+ ++ + K +L Sbjct: 4209 ISLPSFKKGLADQSVPKGTPLVLEVEIEGKPKDVKWYKNGDEIK-DGKVE-DLGNGKYRL 4266 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANT----DAYLT 1217 I D D GEYS N A + +N + + PE + LVP A Sbjct: 4267 TIPDFQEKDVGEYSVTAANE---AGEIESKAKVNVSAK-PEIVSGLVPTTVKQGETATFN 4322 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DA 1273 V++ V WYK I D + T + +L I +D +Y V+ DA Sbjct: 4323 VKVKGPVKGVKWYKNGKEIPDAK--TKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDA 4380 Query: 1274 KSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 S+ L V++ + P+IV +K+G T V + P +W N K I Sbjct: 4381 DSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEI 4439 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 K K + D S SL I + D YK+ + N+ G AD +T+ PG Sbjct: 4440 PNAK-AKDNGDG-SYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTV----KLPGIAI 4493 Query: 1389 ILEIDSSSI---NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNL 1443 + ++ + + + E I + +EI ++ K Q I + Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPDA 4553 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 + + ++ +E D + + + + P + K L++ I+L Sbjct: 4554 GDDDAAEYKVVLTDE----DGNTADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEI 4609 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATY-------ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 G P+ V WY++GK+L A A +N+ YK N+ Sbjct: 4610 ETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEA 4668 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G +S + ++ P IT + +K + E +V P V WYKNG +++ + Sbjct: 4669 GSANSSGKITVE--PKITFL-KPLKDQSITEGENAEFSVETNTKPRIVKWYKNGQEIKPN 4725 Query: 1617 KEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661 + I K T + IK R + Y I NTAG SS ++T+K Sbjct: 4726 SRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLENTAGEAESSAQLTVK 4773 Score = 202 bits (494), Expect = 6e-50 Identities = 265/1127 (23%), Positives = 450/1127 (39%), Gaps = 106/1127 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V +G +L+ P+ +I W G+EI P + + D L I + Sbjct: 4502 VPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQ---LVIPDAGDDD 4557 Query: 705 EGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 Y VV + +G A L +K KEP ++I+ L+ +V G + L + G+P+ Sbjct: 4558 AAEYKVVLTDEDGNTADSSCALTVKLPAKEP-KIIKGLEDQVVSIGSPIKLEIETSGSPK 4616 Query: 764 PTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 T+ W KN K + K + + D + + V+D G Y ++ N G A +S Sbjct: 4617 -TVKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSG 4675 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNNEIISP-S 876 ITVE P +P + Q IT E V N P I WY+N + I P S Sbjct: 4676 KITVE-PKITFLKPL----KDQSITEGENAEFS----VETNTKPRIVKWYKNGQEIKPNS 4726 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 I + +LVI N + D+ YK V N+AG++ A++T+ K K + K Sbjct: 4727 RFIIEQKTDTKYQLVIKNAVRD-DADTYKIVLENTAGEAESSAQLTVKKAKAGLCK-IVK 4784 Query: 937 SYETE---EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXX 991 E + +G ++ E + +W + IS + I + + Sbjct: 4785 GLEDQVVAKGAKMVFEVKIQGEPEDVRWLRDANVISAGANAIIEKIDDTTYRLIIPSADL 4844 Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048 D G V ++ K + PE +R L++ E+ E D + +VE+++ V Sbjct: 4845 KDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDVFKVEVSAPVRQVK 4904 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDES--CTAEVTVVEL 1105 W ++ + IKP + + +K G + +L I + D +Y +L + + C + + + Sbjct: 4905 WYKNDQEIKPNSH-LEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSSAALTVV 4963 Query: 1106 PP---EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLTIDGK 1159 P +I+ L++ V + ++++ +++W+K+G E++ + + Sbjct: 4964 KPNVLKIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESG 5023 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDA- 1214 + L I D G Y +GN K +++ V+ + F+ +T+ Sbjct: 5024 EFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVE 5083 Query: 1215 ---YLTVE--IPDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYT 1267 LT++ I E +V W K V++ ++ T+ ++ TL IR + D +Y Sbjct: 5084 EGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYR 5143 Query: 1268 CVLLD--AKSTTKLKVEVVE-----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 + +T+ KV V E PK V + G V + P+P + Sbjct: 5144 VTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ 5203 Query: 1321 WIVNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 W +N IK + T + + LTI+ V D G K +N G D + Sbjct: 5204 WFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENG-TDETVCEFQQG 5262 Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKT-Q 1437 G + L WD G+ I V+ EW K I T Sbjct: 5263 AGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAH 5322 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS----------DASETTEYYKV-----IKETKIQ-- 1480 T I+N + + R + E DI +ET Y+V ++E K + Sbjct: 5323 TEIRNT-VDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREY 5381 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YE--NRXXX 1535 +P + PL++ T + I L+C +P+ V WY+DG L+ T YE Sbjct: 5382 APKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATL 5441 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKV------G 1587 Y+C+A N HG + TSC V ++ ++ V E K V G Sbjct: 5442 AINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRG 5501 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIE 1646 D + + + G P PE+ WY+NG L N I T+ + + + + E S Y E Sbjct: 5502 DSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561 Query: 1647 ASN------TAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTI 1685 A N T T+ V++ L +KP EG P + E+S SV++ Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSL 5608 Score = 180 bits (439), Expect = 3e-43 Identities = 143/525 (27%), Positives = 224/525 (42%), Gaps = 45/525 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E+++ P FV KLR K +G + FEC+VEG+P P++ W ++PS DF++ YD Sbjct: 642 EKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ 701 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXX 622 A L IR+ P+D G +T +N G S EL V+A P +H Sbjct: 702 T-AKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH--------------- 745 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 + P F + DEG ++ + + P P+I W G+ + E + Sbjct: 746 ---------VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKF 796 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 E + C +L I +V + +G T NR G AS LK++ PP +PL+ Sbjct: 797 ISEDGI---C-ILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRV-PPAPPTFNKPLE 851 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVK 798 V++ +V+ V G P PT+T+ K +K + + I+I K Sbjct: 852 DKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDK 911 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +G KA+N G AE+ A +TVE+ EE+ P F+ ++ TVK V Sbjct: 912 HDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRG 971 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 NP P +TW+ N + + + N + +T +DS +G C A N+ G+ Sbjct: 972 NPNPEVTWFINGHKMDQGSPGVK-IEAHNHDHKLT-IDSAQYAGTVLCRAENAVGRFETK 1029 Query: 919 AR-VTIDVEK----VTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971 AR V + EK FV+ L ET + TV+ E + + WY +E+ D Sbjct: 1030 ARLVVLAPEKQKKPPKFVEILVDKTETVD-NTVVFEVRVEGEPKPTVTWYLKGEELKQSD 1088 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016 EI + D G I+ + + E S K T+ Sbjct: 1089 RVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTV 1133 Score = 177 bits (430), Expect = 4e-42 Identities = 287/1251 (22%), Positives = 485/1251 (38%), Gaps = 155/1251 (12%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 V+ L P G + + P+ +I W++ I PS Q D DN LVI + Sbjct: 4494 VKGLEDAEVPKGKKAVLQVETNKKPK-EIKWYKNGKEITPSDKAQPGSDGDNKPQLVIPD 4552 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 +DA + V + G + D +TV L Sbjct: 4553 AGDDDAAEYKVVLTDEDGNTA------------DSSCALTVK--------------LPAK 4586 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMY 691 P K + Q V GS I LE P+ + W G+E+ ++ I+ D + Y Sbjct: 4587 EPKIIKGLEDQVVSIGSPIKLEIETSGSPKT-VKWYKNGKELPGAAAKTIKIQKIDDNKY 4645 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGE 750 VL+I + G Y V N G A+ + + EP ++PLK + +GE Sbjct: 4646 --VLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGE 4698 Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 + S + PR + W KN KP + DT ++K D Y + Sbjct: 4699 NAEFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVL 4757 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITW 866 EN+ G AE+SA +TV++ + I + E V KG K+V V P + W Sbjct: 4758 ENTAGEAESSAQLTVKKAKAGLCK----IVKGLEDQVVAKGA-KMVFEVKIQGEPEDVRW 4812 Query: 867 YRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 R+ +IS + I + D L+I + D + D+G+Y N +GK+ A+ +D Sbjct: 4813 LRDANVISAGANAIIEKIDDTTYRLIIPSADLK-DAGEYTVEVINESGKAKSDAKGEVD- 4870 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXX 984 EK V+ L+ + E EG + + + S V KWY N +EI H E + G Sbjct: 4871 EKPEIVRGLE-NIEIPEGDDDVFKVEVSAPVRQVKWYKNDQEIKPNSHLEAKKIGPKKYE 4929 Query: 985 XXXXXXXXDVG-----VIKCIVKDQETSTML-VVKETIPEFIRKLQDFEVKEKDVAILEV 1038 D G V+ D ++S L VVK + + + L+D +V+E L+V Sbjct: 4930 LAINRAQLDDGADYKVVLSNAAGDCDSSAALTVVKPNVLKIVDGLKDVDVEEPQPVELKV 4989 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK--LYIRNTSVHDEGEYSCIL-RDES 1095 ++ + W ++G+ +KP + + FE++ + L I ++ D G Y +L D+ Sbjct: 4990 KVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKG 5049 Query: 1096 CTAEVTVVELPP----------EIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDG 1143 +VV + ++ L++ +V +G+ T + + G+ V W KDG Sbjct: 5050 EVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIA-GEPFPEVIWEKDG 5108 Query: 1144 SEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTV--EE 1193 +Q + I ++ +DG L+I D G+Y N S C +T E+ Sbjct: 5109 VVLQKDDRITMRVALDGTAT-LRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQ 5167 Query: 1194 PSI-NFTLRLPEFILVPANTDAY-LTVE-IPDETLDVTWYKKKSVIEDTEKFTL------ 1244 PS F + L +P + + + V +P TL W+ I+ ++ TL Sbjct: 5168 PSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQ--WFLNGIPIKFDDRITLDDMADG 5225 Query: 1245 -----ISDVKKRTLIIRKC---TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296 I DV++ KC E+ E C + + +PP+ + Sbjct: 5226 NYCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWD 5285 Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT--KPSIDSKSASLTIKKVENTD 1354 RI G + + A P EW + K I+ HT + ++D + + I E +D Sbjct: 5286 RRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDG-ACRIKIIPFEESD 5344 Query: 1355 AGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 G+Y N G A+ + V IL+ + + + D+ N G Sbjct: 5345 IGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLE---DKTVNGGQPIR 5401 Query: 1413 IYYVVEYQEIDTTEWI--SVKNITKTQTSIQ-------NLKTNSSYR-----FRAYAVNE 1458 + V+ + W + ++TSIQ L N S +R A N Sbjct: 5402 LSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNA 5461 Query: 1459 VDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 + S + +E K + P K L ++ + + L C G P P++ WY Sbjct: 5462 HGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWY 5521 Query: 1517 RDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ--- 1568 R+G+ L+ T + Y+C A N HG+ +T +Q Sbjct: 5522 RNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMAL 5581 Query: 1569 ---QKP----------VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 +KP ++ +S+ + + + E VT G+P P V W K+G L Sbjct: 5582 GKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVT----GLPNPSVKWSKDGGPLIE 5637 Query: 1616 DKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 D + + + V +RIK Y A+N G+++ + +++ D Sbjct: 5638 DSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDD 5688 Score = 176 bits (429), Expect = 5e-42 Identities = 260/1229 (21%), Positives = 496/1229 (40%), Gaps = 133/1229 (10%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VAT 567 AP+F + L+ + ++ E +V G P + WF+ + + +M + + V T Sbjct: 3188 APVFEQGLKKTSVKEKEEIKMEVKVGG-SAPDVEWFKDDKPVSEDGNHEMKKNPETGVFT 3246 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 LV+++ DAG +T A N AG T E EA ++ Sbjct: 3247 LVVKQAATTDAGKYTAKASNPAG----TAESSAEAEVTQS-------------------- 3282 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 LE PTF ++ V L + +P+P + WL G+ + D + +A Sbjct: 3283 -LE--KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEG 3339 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 Y +K ++ G Y A N GEA + PP+ +E L + V+ Sbjct: 3340 SGSYSITIKDARLE--DSGKYACRATNPAGEAKTEANFAV-VKNLVPPEFVEKLSPLEVK 3396 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGV 802 + ES LS +VVG P P++ W K++ P+ + ++ + S+TI ++ D G+ Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQ-GDVGI 3455 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y+ +A N G A T+A + ++ PP F + + + V+E+ T+ L V PVP Sbjct: 3456 YSCRARNEAGEALTTANFGIIR----DSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVP 3511 Query: 863 SITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 ++ W+++++ I+ S ++ + L I E D G Y C A+N AG++ A Sbjct: 3512 NVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGE-DVGVYTCKATNEAGEAKTTAN 3570 Query: 921 VTI--DVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEISGMDHREII 976 + + ++E FV+ L K YE E+GK +++ + KW+ + I+ +D++ +I Sbjct: 3571 MAVQEEIEAPLFVQGL-KPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIA-IDNQHVI 3628 Query: 977 Q---EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 + E D G C ++ V + IP++ + Q E +V Sbjct: 3629 EKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAE----EV 3684 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 L +E ET V E D +++ K NK H + + +N + G++ + Sbjct: 3685 KPLFIEPLKETFAV--EGDTVVLECKVNK-----ESHPQIKFFKNDQPVEIGQHMQLEVL 3737 Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 E ++T+ E + + + VN KA +L +IQF+ ++ Sbjct: 3738 EDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADL--------------KIQFAAKVE 3783 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 + + +L ++ G++ VG++ + T + F + L V Sbjct: 3784 EHVTDESGQL-------EEIGQFET-VGDTASSKTDT-GRGAPEF-VELLRSCTVTEKQQ 3833 Query: 1214 AYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL 1271 A L ++ E + W K+ +E + + D TL T+ D EY C Sbjct: 3834 AILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDGTLTLTFDNVTQADAGEYRCEAE 3893 Query: 1272 DAKSTTKLKVEVV---EFPPKI----VDYEREYR---IKRGSDVTLLVDYQAFPQPNDEW 1321 + + + ++ E PKI D+ + + + G L P+P+ +W Sbjct: 3894 NEYGSAWTEGPIIVTLEGAPKIDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKW 3953 Query: 1322 IVNSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGH--ADVEMNVTIL 1378 N + +K K ++D + LT+ + D Y+ N G +DV + V Sbjct: 3954 YKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDDMDEYRCEASNEFGDVWSDVTLTVKEP 4013 Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQ 1437 + +P + I E + +G + + + + + + ++ TQ Sbjct: 4014 AQVAPGFFKELSAIQVKETETAKFECKVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQ 4073 Query: 1438 TS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTE 1494 I++ KT+ +R N+ ++++ + T + S T ++K L ++ Sbjct: 4074 RLVIEDSKTDDQGNYRIEVSNDAGVANSK--------VPLTVVPSETLKIKKGLTDVNVT 4125 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXXXXXYK 1549 I L+ G P+ V WY+ + + +++ T E+ Y+ Sbjct: 4126 QGTKILLSVEVEGKPKT-VKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYR 4184 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGDEWLVTAVIEGIPPPEV 1604 + D VE+S V + K IS K Q G ++ IEG P +V Sbjct: 4185 VVLSTDSFSVESSATVTVT-KAAEKISLPSFKKGLADQSVPKGTPLVLEVEIEG-KPKDV 4242 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 WYKNG+++++ K ++ + + I + + +Y++ A+N AG + + V Sbjct: 4243 KWYKNGDEIKDGKVEDLGNGKYR--LTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSA 4300 Query: 1665 KPSKPEG--PVIMREISRESVTIEWKPPL 1691 KP G P +++ + ++ K P+ Sbjct: 4301 KPEIVSGLVPTTVKQGETATFNVKVKGPV 4329 Score = 171 bits (417), Expect = 1e-40 Identities = 221/933 (23%), Positives = 381/933 (40%), Gaps = 104/933 (11%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----DDD 563 MAP F+ K++ G + FEC V W + I+ ++ + Sbjct: 2885 MAPKFITKIKDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGH 2944 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 LV+ V PEDAG +TC+ +N AG + L V L + Sbjct: 2945 ITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKA----------- 2993 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 P F + + ++LEC+++ P+P ++WL + I + S+ Sbjct: 2994 ----------PEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQE---SIT 3040 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 +ES + + IT+ + +G YT +A N EG + L T + E P + L++ Sbjct: 3041 VESVEGV--ERVTITSSELSHQGKYTCIAENTEGTSKTEAFL---TVQGEAPVFTKELQN 3095 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----------SDGDTHSITIL 792 + GE ++LS V G+P+P + + ++ K + TK +TH ++ Sbjct: 3096 KELSIGEKLVLSCSVKGSPQPHVDFYSFSETTK-VETKITSSSRIAIEHDQTNTHWRMVI 3154 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 +D Y A NS G A +++ IT + E P+F ++ +VKEK IK+ Sbjct: 3155 SQITKEDIVSYKAIATNSIGTATSTSKITTK------VEAPVFEQGLKKTSVKEKEEIKM 3208 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNS 911 +V P + W+++++ +S + E + ++ + D+G Y ASN Sbjct: 3209 EVKV-GGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNP 3267 Query: 912 AG--KSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 AG +SS A VT +EK TFV+ L + E T+ + + S +W + + + Sbjct: 3268 AGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQ 3327 Query: 969 GMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETI-PEFI 1020 I ++ D G C + + + VVK + PEF+ Sbjct: 3328 TDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFV 3387 Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR--KLYIR 1077 KL EVKEK+ L V+ + + V W +D I N + +K+ + L I Sbjct: 3388 EKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPIS-IDNVHVIQKQTAVGSFSLTIN 3446 Query: 1078 NTSVHDEGEYSCILRDES----CTAEVTVV--ELPPEIITRLQNQKVNKGNKATFEIELT 1131 + D G YSC R+E+ TA ++ +PPE +L+ +V + + T ++++T Sbjct: 3447 DARQGDVGIYSCRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVRE--QETLDLKVT 3504 Query: 1132 K-GDAL--VRWFKDGSEIQFSN-HIQLTIDGK-KQKLKIYDCDLDDAGEYSC----EVGN 1182 G + V WFKD I N HI +G L I +D G Y+C E G Sbjct: 3505 VIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGE 3564 Query: 1183 SKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKK--KSVIE 1237 +K TA + V+E + F L + V A L V + + +V W+K I+ Sbjct: 3565 AKTTANMAVQEEIEAPLFVQGLKPY-EVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAID 3623 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTT--KLKVEVVEF------- 1286 + + TL+I+ D +YTC + K T +LK+ F Sbjct: 3624 NQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAGKDETVGELKIPKYSFEKQTAEE 3683 Query: 1287 -PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSKSAS 1344 P ++ +E G V L P ++ N + ++ +H + + + + Sbjct: 3684 VKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIK 3743 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 LTI+ + D G Y+ N G A+ ++ I Sbjct: 3744 LTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776 Score = 169 bits (412), Expect = 5e-40 Identities = 255/1135 (22%), Positives = 433/1135 (38%), Gaps = 126/1135 (11%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 TF K K Q + EG + P + W G+EI P+ + ++D Y V Sbjct: 4684 TFLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTK-YQLV 4741 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 +K N + TY +V N GEA L +K + ++++ L+ +V +G ++ Sbjct: 4742 IK--NAVRDDADTYKIVLENTAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVF 4799 Query: 755 SAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 ++ G P + W ++ + A + K D T+ + I+ +KD G YT++ N Sbjct: 4800 EVKIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRL-IIPSADLKDAGEYTVEVINE 4857 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A++ A V+E E + + I + E V+ PV + WY+N+ Sbjct: 4858 SGKAKSDAKGEVDEKPE-------IVRGLENIEIPEGDDDVFKVEVSA-PVRQVKWYKND 4909 Query: 871 EIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + I P+ + G + EL I + D DYK V SN+AG A +T+ V Sbjct: 4910 QEIKPNSHLEAKKIGPKKYELAINRAQLD-DGADYKVVLSNAAGDCDSSAALTVVKPNVL 4968 Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEIS----GMDHREIIQEGRXXXX 984 + K + EE + V L+ + KWY N +E+ G E + G Sbjct: 4969 KIVDGLKDVDVEEPQPVELKVKVEGIPKVIKWYKNGQELKPDADGFKFEEKPESGEFSLT 5028 Query: 985 XXXXXXXXDVGVIKCIV---KDQETSTMLV----VKETIP----EFIRKLQDFEVKEKDV 1033 D G + ++ K + S +V K + P F+ L+D EV+E D+ Sbjct: 5029 IPSSKKS-DGGAYRVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDM 5087 Query: 1034 AILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 L+ I E +V+WE+DG +++ L IR+ D G+Y + Sbjct: 5088 LTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAKKSDIGQYRVTAK 5147 Query: 1093 DESCTA----EVTVVEL-----PPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKD 1142 +E+ +A +VTV E P+ + L+ G+K F +++ ++WF + Sbjct: 5148 NEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLN 5207 Query: 1143 GSEIQFSNHIQLT--IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-------E 1193 G I+F + I L DG L I D +D G C N T E + Sbjct: 5208 GIPIKFDDRITLDDMADGN-YCLTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHD 5266 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP---------DETLDVTWYKKKSVIEDTEKFTL 1244 LR P VP D + V P + T +V W+K IE T + Sbjct: 5267 DGSRDDLRYPPRFNVPL-WDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEI 5325 Query: 1245 ISDVKKRTLI-IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE---------FPPKI 1290 + V I I E D Y CV ++ A++ +VE++E + PKI Sbjct: 5326 RNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKI 5385 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-SASLTIKK 1349 + + G + L A P+ + W + ++ T + +A+L I Sbjct: 5386 NPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIND 5445 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 D G Y+ N G + +V + K + + W + G+ Sbjct: 5446 STEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWAD---RGD 5502 Query: 1410 STIIYYVVEYQEIDTTEWIS----VKNITKT--QTSIQ---NLKTNSSYR-----FRAYA 1455 S + V +W ++N +T +TS +L N S +R A Sbjct: 5503 SFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCEA 5562 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKP------LKNITTEPNEDIELTCIFGGVP 1509 N + T + +T+ KP L +++ I+L C G+P Sbjct: 5563 ENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLP 5622 Query: 1510 QPKVTWYRDGKKL-KTAKATYENRXX-----XXXXXXXXXXXXXYKCIAFNDHGEVET-- 1561 P V W +DG L + ++ + N Y+C+A N++G T Sbjct: 5623 NPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKS 5682 Query: 1562 ---------SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 S VV Q P T+ D++ G + ++ P PE++WYK+G Sbjct: 5683 FVRMDDGLGSGVVTASQPPRFTLKMGDVRTTE--GQPLKLECKVDASPLPEMVWYKDGAI 5740 Query: 1613 LENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + I+ + + + + I Y + A+N +GT+ + T V P Sbjct: 5741 VTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLP 5795 Score = 156 bits (379), Expect = 5e-36 Identities = 258/1109 (23%), Positives = 438/1109 (39%), Gaps = 156/1109 (14%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F++ L+ + +G +F + PR + W++ IKP+ F + D LVI+ Sbjct: 4685 FLKPLKDQSITEGENAEFSVETNTKPRI-VKWYKNGQEIKPNSRFIIEQKTDTKYQLVIK 4743 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 +DA T+ V +N AG A S+ +L V+ I++G Sbjct: 4744 NAVRDDADTYKIVLENTAGEAESSAQLTVKK------------------AKAGLCKIVKG 4785 Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + + Q V +G+ ++ E ++ PE D+ WL I N ++ + D Y Sbjct: 4786 L--------EDQVVAKGAKMVFEVKIQGEPE-DVRWLRDANVISAGAN-AIIEKIDDTTY 4835 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 ++ ++K G YTV +N G+A K E P+++ L+++ + +G+ Sbjct: 4836 RLIIPSADLK--DAGEYTVEVINESGKAKSDA----KGEVDEKPEIVRGLENIEIPEGDD 4889 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + +V P + W KN++ +K L K G + ++ D Y + Sbjct: 4890 DVFKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLS 4948 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N+ G ++SA +TV +P ++ +++ V+E ++L +V P I WY+ Sbjct: 4949 NAAGDCDSSAALTVVKPNVLK-----IVDGLKDVDVEEPQPVELKVKVEGIP-KVIKWYK 5002 Query: 869 NNEIISP-SETITQNFDGENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTIDVE 926 N + + P ++ E+ E +T S+ D G Y+ V N G+ G+ V + Sbjct: 5003 NGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSVVHVKSA 5062 Query: 927 K-------VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH--REI 975 K F+ L K E EEG + L+C + + W + + D + Sbjct: 5063 KSSEPTSGANFLSPL-KDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRV 5121 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---------PEFIRKLQDF 1026 +G D+G + K++ S K T+ P+F+ L+ Sbjct: 5122 ALDG-TATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTG 5180 Query: 1027 EVKEKDVAILEVEINSETADVV-WERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 D V++ + W +G IK + D G+ L IR+ D Sbjct: 5181 AALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYC-LTIRDVREEDF 5239 Query: 1085 GEYSCILRDESCTAEVTVVEL----------------PPEIITRLQNQKVNKGNKATFEI 1128 G CI ++E+ T E TV E PP L ++++ G+ E Sbjct: 5240 GTLKCIAKNENGTDE-TVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIEC 5298 Query: 1129 ELTKGD-ALVRWFKDGSEIQFSNHIQL--TIDGKKQKLKIYDCDLDDAGEYSC----EVG 1181 + A V WFKDG +I+ + H ++ T+DG ++KI + D G Y C E+G Sbjct: 5299 HVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGAC-RIKIIPFEESDIGVYMCVAVNELG 5357 Query: 1182 NSKCTAILTVE-------------EPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227 ++ A VE P IN L E V L+ ++ V Sbjct: 5358 QAETQATYQVEILEHVEEEKRREYAPKINPPL---EDKTVNGGQPIRLSCKVDAIPRASV 5414 Query: 1228 TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285 WYK + D+ + TL I TE+D Y CV +A T V V+ Sbjct: 5415 VWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVK 5474 Query: 1286 FPPKIVDYEREYRI----------KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT- 1334 P + V E E RG TL P P +W N ++++ T Sbjct: 5475 VPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTV 5534 Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------VEMNVTILDKPS-PPGK 1386 + S D S SLT+ + +D GIY+ EN G A V+M + +KP GK Sbjct: 5535 IETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593 Query: 1387 PN--ILEIDSSSI---NICWDEPENTG--NSTIIYYVVEYQEIDTT--EWISVKNITKTQ 1437 P ILE+ S+ N+ E + TG N ++ + I+ + EW + + Q Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE-------TKIQSPTVEKPLKN 1490 I+N + +R A NE + S TT+ + + + T Q P + + Sbjct: 5654 LRIKNATVHDEGTYRCVATNE----NGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGD 5709 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 + T + ++L C P P++ WY+DG Sbjct: 5710 VRTTEGQPLKLECKVDASPLPEMVWYKDG 5738 Score = 149 bits (361), Expect = 8e-34 Identities = 173/749 (23%), Positives = 292/749 (38%), Gaps = 93/749 (12%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S E + F+ L+ +G + +C + G P P++ W + +++ M Sbjct: 5064 SSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVAL 5123 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 D ATL IR D G + AKN AG A+S ++ V ++ G + + Sbjct: 5124 DGTATLRIRSAKKSDIGQYRVTAKNEAGSATSDCKVTV----TEQGEQPS---------- 5169 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 P F K G ++ +P+P + W G I D+ I++ Sbjct: 5170 ----------KPKFVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRITL 5219 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--------P 734 +D + YC L I +V++ GT +A N G + G + P Sbjct: 5220 DDMADGN-YC--LTIRDVREEDFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276 Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793 P+ PL + G+ + + V NP + W K+ K ++ T+ +K Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336 Query: 794 --PKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAE---PPLFINRFQEITVKE 846 P + D GVY A N G AET A VE E EE P ++ TV Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 I+L +V P S+ WY++ + + ++ + + N +E D G Y+C Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRC 5456 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--------EEGKTVILECQTSHTV-- 956 VA+N+ G + V + V K K ++ + T + G + L+C + Sbjct: 5457 VATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFP 5516 Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXX--XXXXDVGVIKCIV-------KDQETS 1007 KWY N + + R +I+ D G+ +C K Q T+ Sbjct: 5517 EIKWYRNGQLLRN-GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATA 5575 Query: 1008 -TMLVVKETI---------PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EI 1055 + + +T P+FI +L D V +V LE ++ V W +DG + Sbjct: 5576 HVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPL 5635 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--------------VT 1101 I+ + ++ E + +L I+N +VHDEG Y C+ +E+ +A V Sbjct: 5636 IEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVV 5695 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DG 1158 PP ++ + + +G E ++ + W+KDG+ + S+ IQ+++ DG Sbjct: 5696 TASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDG 5755 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 L I C DD G Y N TA Sbjct: 5756 -VATLLIPSCVYDDDGIYRVIATNPSGTA 5783 Score = 143 bits (346), Expect = 5e-32 Identities = 105/438 (23%), Positives = 181/438 (41%), Gaps = 41/438 (9%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 + + AP L K G ++ C+V+ PR + W++ ++ + Y++D Sbjct: 5377 KRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEED 5436 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 ATL I + ED G + CVA NA G +++ + V+ P + E Sbjct: 5437 GTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE------------- 5483 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 G P F+K + D G L+C + P P+I W G+ + Sbjct: 5484 -------GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLL--RNGPRTV 5534 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA----------SLPIVLKIKTGEKE 733 IE+ CS L + EG Y A N G+A +L K K E + Sbjct: 5535 IETSPDGSCS-LTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGK 5593 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790 PP+ I L M V G + L +V G P P++ W K+ P+ ++ Sbjct: 5594 PPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQ 5653 Query: 791 I-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN----AEPPLFINRFQEITVK 845 + +K V DEG Y A N G A T + + +++ ++PP F + ++ Sbjct: 5654 LRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTT 5713 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 E +KL +V +P+P + WY++ I++PS+ I + + + ++ D G Y+ Sbjct: 5714 EGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYR 5773 Query: 906 CVASNSAGKSSHGARVTI 923 +A+N +G + T+ Sbjct: 5774 VIATNPSGTAQDKGTATV 5791 Score = 141 bits (342), Expect = 2e-31 Identities = 270/1279 (21%), Positives = 483/1279 (37%), Gaps = 84/1279 (6%) Query: 151 VTLEKSDLFDSQEDESKPD-VSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKI 209 +T E + S + E P+ V + P++ ++ KS K I E + K + +V EK Sbjct: 1515 MTHESEESRTSVKKEKTPEKVDEKPKSPTKKDKSPEKSITEEIKSPVKKEKSPEKVEEKP 1574 Query: 210 NVPDDKETS-QTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXX--X 266 P KE S + P S K+S+ +K K+ + E + P+ Sbjct: 1575 ASPTKKEKSPEKPASPTKKSE-NEVKSPTKKEKSPEKSVVEELKSPKEKSPEKADDKPKS 1633 Query: 267 XXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQ 326 E S K +KS K S KP +K K +K Sbjct: 1634 PTKKEKSPEKSATEDVKSPTKKEKSPEKVEEKPTSPTKKESSPTKKTDDEVKSPTKKEKS 1693 Query: 327 VFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRK 386 + P + + P S + V+S K+++ E++ KE PE+ K Sbjct: 1694 PQTVEEKPASPTKKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVK 1753 Query: 387 SSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLY 446 S +K ++ ++ +K +P + +PV++ D V + T + + + E Sbjct: 1754 SPTKK-EKSPEKSAEEKPKSPTKKESSPVKM-ADDEV------KSPTKKEKSPEKVEEKP 1805 Query: 447 ILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQ 506 T + +K EE P + ++ T+ + EK + P EKP S Sbjct: 1806 ASPTKKEKT--PEKSAAEELK-SPTKKEKSPSSPTKKTGDESKEKSPEKPE-EKPKSPTP 1861 Query: 507 SMAPIFVEKLRPKHTPDGST-----VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 +P K + +P+ + + +++ + + F +++ + + + + D Sbjct: 1862 KKSPPGSPKKKKSKSPEAEKPPAPKLTRDLKLQTVNKTDLAHFE--VVVEHATECKWFLD 1919 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 + T V +D F C + + F S T ++ + GS T Sbjct: 1920 GKEITTAQGVTVSKDDQFEFRC-SIDTTMFGSGTVSVVAS---NAAGSVETKTELKVLET 1975 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 E P F+ K + V +G + ++ ++A+ P W G ++ D Sbjct: 1976 PK------ETKKPEFTDKLRDMEVTKGDTVQMD--VIALHSPLYKWYQNGN-LLEDGKNG 2026 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 V I+++ + S L I N + G TV A N G + L + P V++ Sbjct: 2027 VTIKNEENK--SSLIIPNAQ--DSGKITVEASNEVGSSESSAQLTVNP-PSTTPIVVDGP 2081 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801 KS+ +++ E+ A + G P PT+ W N K V+ T + T + LK K E Sbjct: 2082 KSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQ 2141 Query: 802 VYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-R 858 T+K A+NS G A + V E N + P F ++ + E ++ + Sbjct: 2142 TGTVKVTAQNSAGQDSKQADLKV----EPNVKAPKFKSQLTDKVADEGEPLRWNLELDGP 2197 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 +P ++W N + ++ S+T+ G+ + I E+ SG A N+AG+ Sbjct: 2198 SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKPEM-SGTLTAKAKNAAGECET 2256 Query: 918 GARVTID--VEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHRE 974 A+VT++ +K FV+ Q T E T + + WY N K++ + + Sbjct: 2257 SAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVK 2316 Query: 975 I--IQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLVVKET-IPEFIRKLQDF 1026 + + E G I+ K Q T+ + V K+T +P+F + D Sbjct: 2317 VKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFTTNMDDR 2376 Query: 1027 EVKE-KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 +VKE +DV V W +GE + N +K G + I + G Sbjct: 2377 QVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGE-HTIEISAVTPEQAG 2435 Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE--IELTKGDALV 1137 E SC + V V P L+++ + +G + + + K + Sbjct: 2436 ELSCEATNPVGSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKI 2495 Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYS----CEVGNSKCTAILTVE 1192 W KDG EI H ++ + KL I L+D G + E G ++C+A L V Sbjct: 2496 TWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVV 2555 Query: 1193 E--PSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248 + P F + L +T + D T V WY ++ TE + + Sbjct: 2556 KGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNAN 2615 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDV 1305 T+ I T D + CV + + + P V++E + + G + Sbjct: 2616 GVYTMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTL 2675 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 L P+P W VN K +++ ++ K + + ++TIK + +G N Sbjct: 2676 KLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINE 2735 Query: 1366 CGHADVEMNVTILDKPSPP 1384 G A E + +L + PP Sbjct: 2736 YGKATSEATLLVLPRGEPP 2754 Score = 133 bits (321), Expect = 6e-29 Identities = 185/819 (22%), Positives = 326/819 (39%), Gaps = 81/819 (9%) Query: 936 KSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ----EGRXXXXXXXXX 989 K + ++G + + EC T V KW + KEI + + EG Sbjct: 2894 KDTKAKKGHSAVFECVVPDTKGVCCKWLKDGKEIELIARIRVQTRTGPEGHITQELVLDN 2953 Query: 990 XX-XDVGVIKCIV-----KDQETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAIL 1036 D G CIV KD +T+ V++ + PEFI LQD K + +L Sbjct: 2954 VTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVL 3013 Query: 1037 EVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 E ++ E V W D + I + E + ++ I ++ + +G+Y+CI + Sbjct: 3014 ECKVIGEPKPKVSWLHDNKTIT--QESITVESVEGVERVTITSSELSHQGKYTCIAENTE 3071 Query: 1096 CTAE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--------ALVRWFKDG 1143 T++ +TV P LQN++++ G K + KG + K Sbjct: 3072 GTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSV-KGSPQPHVDFYSFSETTKVE 3130 Query: 1144 SEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYSCEVGNSKCTAILT------VEEPS 1195 ++I S+ I + D ++ I +D Y NS TA T VE P Sbjct: 3131 TKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPV 3190 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIED-TEKFTLISDVKKRTL 1253 L+ V + + V++ DV W+K K V ED + + TL Sbjct: 3191 FEQGLKKTS---VKEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTL 3247 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLV 1309 ++++ D +YT + T + + EV + P V +K TL V Sbjct: 3248 VVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKINETATLSV 3307 Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCG 1367 + P P+ EW+ + + ++ H ++ S S S+TIK D+G Y R N G Sbjct: 3308 TVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAG 3367 Query: 1368 HADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 A E N ++ PP K + LE+ + T + VE+ + DT Sbjct: 3368 EAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPS-----VEWFKDDT 3422 Query: 1425 TEWISVKNITKTQTSIQ--NLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 I ++ + QT++ +L N + + Y+ + + + TT + +I+++ Sbjct: 3423 PISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS--I 3480 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKATYENRXX 1534 P + L+ + E ++L G P P V W++D K + AK Sbjct: 3481 PPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHT 3540 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVT 1593 Y C A N+ GE +T+ + +Q++ + + +K + + G + Sbjct: 3541 LTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAELV 3600 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEASNTA 1651 +EG P PEV W+K+G + D ++ I K + + + IK+ + KYT +A+N A Sbjct: 3601 VRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKA 3660 Query: 1652 GTSSVEVTLKV----YDKPSKPEGPVIMREISRESVTIE 1686 G LK+ ++K + E + E +E+ +E Sbjct: 3661 GKDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVE 3699 Score = 131 bits (316), Expect = 2e-28 Identities = 145/606 (23%), Positives = 250/606 (41%), Gaps = 53/606 (8%) Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 ++ P PDI W ++ DE + + D + I V+ G YT +A N Sbjct: 570 KVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFF---AMTIDPVQVTDTGRYTCMATNE 626 Query: 716 EGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 G+AS ++ EKE PP + L+ ++G+ + +V G P P + W +++ Sbjct: 627 YGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQ 686 Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 P++ + DG T + I + + D GVYT+K +N G E+ A + V+ ++N Sbjct: 687 PLRPSHDFRLQYDGQTAKLEI-RDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNH 745 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P F + + E ++ + +T +P P I W+ N + +S SE + + L Sbjct: 746 VAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICIL 805 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--TFVKHLQKSYETEEGKTVIL 948 I +V D G C SN G +S R+ + V TF K L+ +E TV+ Sbjct: 806 TIKDVTRHFD-GMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDK-TVQEKSTVVF 863 Query: 949 ECQTS---HTVSTKWYHNKKEISGMDHREII-QEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 E S T K+ +G + EI+ +G G I +++ Sbjct: 864 EVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNE 923 Query: 1005 ----ETSTMLVVKE------TIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG 1053 E+ L V++ + P F++ ++D VK + A+ E + + +V W +G Sbjct: 924 HGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFING 983 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV----E 1104 + E H KL I S G C + R E+ V + + Sbjct: 984 HKMDQGSPGVKIEAHNHDHKLTI--DSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQK 1041 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 PP+ + L ++ N FE+ + + V W+ G E++ S+ +++ K+ Sbjct: 1042 KPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKI 1101 Query: 1164 KIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 I + ++DAGE NS + A LTV++ PEF L P + LTVE Sbjct: 1102 SIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPF-----APEFDLRPVS----LTVE 1152 Query: 1220 IPDETL 1225 E + Sbjct: 1153 KGSEAV 1158 Score = 130 bits (313), Expect = 5e-28 Identities = 111/453 (24%), Positives = 192/453 (42%), Gaps = 53/453 (11%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 K +++ P F + L G + +C V G P P+I W+R +++ + Sbjct: 5477 KQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIE 5536 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619 D +L + E D G + C A+NA G A + V+ L Sbjct: 5537 TSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALG-------------- 5582 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 + EG PP F + V G+ I LEC++ +P P + W G ++ D Sbjct: 5583 --KTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSR 5640 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-------EK 732 + E+ +Y L+I N EGTY VA N G A+ +++ G Sbjct: 5641 FEWSNEASKGVY--QLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTAS 5698 Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--- 789 +PP+ + + +G+ + L +V +P P + W K+ A+ T SD S+ Sbjct: 5699 QPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG----AIVTPSDRIQISLSPD 5754 Query: 790 ---TILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE-PTEENA------------EP 832 T+L P V D+G+Y + A N G A+ TV++ P + A + Sbjct: 5755 GVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKA 5814 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP--SETITQNFDGENIEL 890 P + + I + EK + +L + + +P P+I W+++ E + P + ++ DG EL Sbjct: 5815 PKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGV-CEL 5873 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 V+ + + D+G Y+CVA N+ G + V + Sbjct: 5874 VVDSATRQ-DAGGYRCVAENTYGSARTSCDVNV 5905 Score = 127 bits (306), Expect = 4e-27 Identities = 118/459 (25%), Positives = 185/459 (40%), Gaps = 50/459 (10%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 + + AP +E L P+ + + C+ G P+P I WF+ + P Q+ D Sbjct: 5810 DANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDG 5869 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 V LV+ +DAG + CVA+N G S+ T V D Sbjct: 5870 VCELVVDSATRQDAGGYRCVAENTYG--SARTSCDVNVIRGDRKPR------------DI 5915 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 + I EG P F+ + G + EC P P I WL G E+ DE I + Sbjct: 5916 DSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEA 5975 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-------------TGE 731 +D L +++V EG + VA N G AS L I+ GE Sbjct: 5976 AAD---GTQRLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGE 6032 Query: 732 KE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALPTKS 782 E P++ L +M + +G V + G P PT+ W K+ + + K + Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092 Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAE-------PPL 834 + H + I+ DEG Y+L+A N G A+T + + P +A+ PP Sbjct: 6093 ERGIHHLVIVNASP-DDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPG 6151 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVIT 893 F+ + + V V +P P + W+ N + I P I Q+ G + L+I Sbjct: 6152 FVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIIL 6211 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + E D+G+Y A NS G +S A + + V + +K Sbjct: 6212 DTTLE-DAGEYVATAKNSHGSASSSAVLDVTVPFLDSIK 6249 Score = 121 bits (292), Expect = 2e-25 Identities = 224/1007 (22%), Positives = 371/1007 (36%), Gaps = 136/1007 (13%) Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528 +P+ L D YT E I++ + E P V L P+G Sbjct: 4839 IPSADLKDAGEYTV-------EVINESGKAKSDAKGEVDEKPEIVRGLENIEIPEGDDDV 4891 Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 F+ +V P Q+ W++ IKP+ + L I +D + V NA Sbjct: 4892 FKVEVSA-PVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNA 4950 Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 AG S+ L V P I++G+ ++P+ Sbjct: 4951 AGDCDSSAALTVVKP--------------------NVLKIVDGLKDVDVEEPQ------- 4983 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 + L+ ++ IP+ I W G+E+ PD + E L I + KK G Y Sbjct: 4984 -PVELKVKVEGIPKV-IKWYKNGQELKPDAD-GFKFEEKPESGEFSLTIPSSKKSDGGAY 5040 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP----QVIEPLKSMIVRQGESVILSAQVVGNPRP 764 VV N +GE V+ +K+ + P + PLK V +G+ + L + G P P Sbjct: 5041 RVVLGNDKGEVYSGSVVHVKSAKSSEPTSGANFLSPLKDTEVEEGDMLTLQCTIAGEPFP 5100 Query: 765 TITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 + W K+ ++ + DG T ++ I KK D G Y + A+N G A + Sbjct: 5101 EVIWEKDGVVLQKDDRITMRVALDG-TATLRIRSAKK-SDIGQYRVTAKNEAGSATSDCK 5158 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 +TV E E+ ++P F+ + + +V P P++ W+ N I + I Sbjct: 5159 VTVTEQGEQPSKPK-FVIPLKTGAALPGDKKEFNVKVRGLPKPTLQWFLNGIPIKFDDRI 5217 Query: 880 T-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGK----------SSHGARVTIDVEKV 928 T + N L I +V E D G KC+A N G + H D+ Sbjct: 5218 TLDDMADGNYCLTIRDVREE-DFGTLKCIAKNENGTDETVCEFQQGAGHDDGSRDDLRYP 5276 Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXX 985 G + +EC + T +W+ + K+I H EI Sbjct: 5277 PRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIK 5336 Query: 986 XXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----------KETIPEFIRKLQDFEVKE 1030 D+GV C+ ++ ET V +E P+ L+D V Sbjct: 5337 IIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEEEKRREYAPKINPPLEDKTVNG 5396 Query: 1031 KDVAILEVEINS-ETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 L ++++ A VVW +DG ++ + +E+ G L I +++ D G Y Sbjct: 5397 GQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDG-TATLAINDSTEEDIGAYR 5455 Query: 1089 CILR------DESCTAEVTVVEL-------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 C+ + SC+ V V + P L + ++G+ T + +T GD Sbjct: 5456 CVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVT-GDP 5514 Query: 1136 L--VRWFKDGSEIQFSNH--IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187 ++W+++G ++ I+ + DG L + + + D G Y CE G +K A Sbjct: 5515 FPEIKWYRNGQLLRNGPRTVIETSPDG-SCSLTVNESTMSDEGIYRCEAENAHGKAKTQA 5573 Query: 1188 ILTV-------EEPSINFTLRLPEFILVPANTDAYLTVEIPDE-------TLDVTWYKKK 1233 V E+P ++ + P+FIL ++ L I E V W K Sbjct: 5574 TAHVQMALGKTEKPKMD-EGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDG 5632 Query: 1234 SVIEDTEKFTLISDVKKRT--LIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEV------ 1283 + + +F ++ K L I+ T D+ Y CV + +TTK V + Sbjct: 5633 GPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATTKSFVRMDDGLGS 5692 Query: 1284 ----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 PP+ + R G + L A P P W + I+ + S+ Sbjct: 5693 GVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLS 5752 Query: 1340 SKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 A+L I D GIY++ N G A + T+ P G Sbjct: 5753 PDGVATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSG 5799 Score = 116 bits (278), Expect = 9e-24 Identities = 116/476 (24%), Positives = 194/476 (40%), Gaps = 53/476 (11%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 EKP +E P F+ +L G+ + EC+V G P P + W + + F+ Sbjct: 5585 EKPKMDE-GKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEW 5643 Query: 559 YYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617 + V L I+ D GT+ CVA N G S+TT+ V D G V Sbjct: 5644 SNEASKGVYQLRIKNATVHDEGTYRCVATNENG--SATTKSFVRM---DDGLGSGVVTAS 5698 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 PP F+ K EG + LEC++ A P P++ W G + P Sbjct: 5699 Q--------------PPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPS 5744 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732 + I +++ D + L I + +G Y V+A N G A +K +G + Sbjct: 5745 DRIQISLSPDG---VATLLIPSCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGAR 5801 Query: 733 -----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKAL 778 + P+++EPL+++ + + +S L + G+P+PTI W K+ + P L Sbjct: 5802 RSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRL 5861 Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTE-----EN 829 D ++ +D G Y AEN+ G A TS + V +P + Sbjct: 5862 QLIESPDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIRE 5921 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 + P F K ++ NP PSI W ++ + E I + + Sbjct: 5922 GKAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQ 5981 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGK 944 +I + + + G ++CVA+N G +S A + I+ ++ + L + + E EE K Sbjct: 5982 RLILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECK 6037 Score = 114 bits (274), Expect = 3e-23 Identities = 135/593 (22%), Positives = 242/593 (40%), Gaps = 45/593 (7%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 P++ L+ Q VNK + A FE+ + +WF DG EI + + ++ D + + + Sbjct: 1885 PKLTRDLKLQTVNKTDLAHFEVVVEHATEC-KWFLDGKEITTAQGVTVSKDDQFE----F 1939 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ET- 1224 C +D S V A +VE + L P+ P TD +E+ +T Sbjct: 1940 RCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTV 1999 Query: 1225 -LDVT--------WYKKKSVIEDTEK-FTLISDVKKRTLIIRKCTEDDQC--EYTCVLLD 1272 +DV WY+ +++ED + T+ ++ K +LII + + E + + Sbjct: 2000 QMDVIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGS 2059 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 ++S+ +L V P +VD + IK FP P +W +N KI+++ + Sbjct: 2060 SESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESR 2119 Query: 1333 H--TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 T + D + ++ K+E T G K+ +N+ G + ++ + P + L Sbjct: 2120 TITTIKTEDVYTLKISNAKIEQT--GTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQL 2177 Query: 1391 --EIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKT 1445 ++ + W+ E + T + +++ Q + ++ + V + +I K Sbjct: 2178 TDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTIAEAKP 2237 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 S A A N A E KV + P + +N T E ++ + I Sbjct: 2238 EMSGTLTAKAKNA-----AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIV 2292 Query: 1506 GGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCI---AFNDHGEV 1559 G P P VTWY + KKL + K Y + I A N G+V Sbjct: 2293 TGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKV 2352 Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 + + + + +K + +N D +Q K G++ TA +EG P P V W NG + Sbjct: 2353 QATAQLKVDKKTEVPKFTTNMDDRQV-KEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHP 2411 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL---KVYDKPS 1667 +T K+ I I + + + + EA+N G+ +V L KV D P+ Sbjct: 2412 NITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPT 2464 Score = 112 bits (269), Expect = 1e-22 Identities = 206/1012 (20%), Positives = 379/1012 (37%), Gaps = 71/1012 (7%) Query: 726 KIKTGEKEP-PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKS 782 K EK P P++ LK V + + + +VV W + K + T S Sbjct: 1875 KSPEAEKPPAPKLTRDLKLQTVNKTD--LAHFEVVVEHATECKWFLDGKEITTAQGVTVS 1932 Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842 D + G ++ A N+ G ET + V E +E +P F ++ +++ Sbjct: 1933 KDDQFEFRCSIDTTMFGSGTVSVVASNAAGSVETKTELKVLETPKETKKPE-FTDKLRDM 1991 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDS 901 V + T+++ +P+ WY+N ++ + +T + L+I N DS Sbjct: 1992 EVTKGDTVQMDVIALHSPL--YKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQ---DS 2046 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILECQTSH--TVST 958 G ASN G S A++T++ T V KS +E +T + S + Sbjct: 2047 GKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTV 2106 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM-LVVKE 1014 KW N+K + I+ G +K ++ Q++ L V+ Sbjct: 2107 KWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKVTAQNSAGQDSKQADLKVEP 2166 Query: 1015 TI--PEFIRKLQDFEVKEKDVAILEVEIN--SETADVVWERDGEIIKPKKNKYDFEKRGH 1070 + P+F +L D E + +E++ S +V W +G+ + + Sbjct: 2167 NVKAPKFKSQLTDKVADEGEPLRWNLELDGPSPGTEVSWLLNGQPLTKSDTVQVVDHGDG 2226 Query: 1071 IRKLYIRNTSVHDEGEYSCILRDES--C--TAEVTVV--ELPPEIITRLQNQKVNKGNKA 1124 + I G + ++ + C +A+VTV PE + QN + Sbjct: 2227 TYHVTIAEAKPEMSGTLTAKAKNAAGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESV 2286 Query: 1125 TFEIELT-KGDALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEV- 1180 F +T K V W+ + ++ S +++ + K ++I ++ G E Sbjct: 2287 KFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAE 2346 Query: 1181 ---GNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKS 1234 G + TA L V++ + FT + + V D T + V W Sbjct: 2347 NVSGKVQATAQLKVDKKTEVPKFTTNMDDR-QVKEGEDVKFTANVEGYPEPSVAWTLNGE 2405 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDD----QCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290 + T+ + T+ I T + CE T + K +L V+ V P Sbjct: 2406 PVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPVGSKKRDVQLAVKKVGDAPTF 2465 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTK-PSIDSKSASLTI 1347 + I G ++TL+ P+P W+ + I H K + S L+I Sbjct: 2466 AKNLEDRLITEG-ELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSI 2524 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN- 1406 + + D G ++ E+ G A+ ++ ++ K P KP + D + IN+ + Sbjct: 2525 LQTKLEDKGRITIKAESEFGVAECSASLGVV-KGRPMAKP-AFQSDIAPINLTEGDTLEC 2582 Query: 1407 ----TGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460 TG+ T + + + Q + TE + N T I + + + + + A N+ Sbjct: 2583 KLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCVAYNKA- 2641 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + S T KV+ ++ E L + T + ++L + G P+P V+WY +GK Sbjct: 2642 -GEVS-TEGPLKVVAPIPVE---FETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGK 2696 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYK----CIAFNDHGEVETSCVVGIQQKPVITIS 1576 KL+ ++ + Y C A N++G+ + + + + Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756 Query: 1577 NEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 E + + + G + + V G P P + WY N ++ N Y I T +KTS + I Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816 Query: 1636 KRS-HSSKYTIEASNTAGTSSVEVTLKVY--DKPSKPEGPVIMREISRESVT 1684 H + +A N AG S + Y D S+ E E + +T Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAEEFVGDDLT 2868 Score = 111 bits (268), Expect = 2e-22 Identities = 145/628 (23%), Positives = 251/628 (39%), Gaps = 53/628 (8%) Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804 Q S + +V G P P ITW K++ + + SD D + P +V D G YT Sbjct: 561 QESSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYT 620 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N G A TSA V + E+ A PP F+ + ++ KE I V P P + Sbjct: 621 CMATNEYGQASTSAFFRVLK-VEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPEL 679 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923 W +++ + PS +DG+ +L I + + D+G Y N G A + + Sbjct: 680 VWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPD-DTGVYTVKIQNEFGSIESKAELFVQ 738 Query: 924 -DVEKVTFVKHLQKSYE---TEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977 D +K Q + E +EG+ V + + + + W+ N K +S + + I Sbjct: 739 ADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFIS 798 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM------LVVKETIPEFIRKLQDFEVKEK 1031 E G++ C ++ S + V P F + L+D V+EK Sbjct: 799 EDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEK 858 Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYS 1088 + EV+++ + + G+ +K + + ++ I NTS+ HD GE Sbjct: 859 STVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHD-GEIV 917 Query: 1089 CILRDESCTAE----VTVVE------LPPEIITRLQNQKVNKGNKATFEIELTKG-DALV 1137 ++E TAE +TV + P + +++Q V G A FE + + V Sbjct: 918 AKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEV 977 Query: 1138 RWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192 WF +G ++ Q S +++ KL I AG C VG + A L V Sbjct: 978 TWFINGHKMDQGSPGVKIEAHNHDHKLTIDSAQY--AGTVLCRAENAVGRFETKARLVVL 1035 Query: 1193 EPSINFTLRLPEFILVPAN----TDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245 P + P+F+ + + D + E+ E VTWY K ++ +++ + Sbjct: 1036 APEKQ--KKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIR 1093 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKST----TKLKVEVVEFPPKIVDYEREYRIKR 1301 + I+ +D E V +++ + KL V+ F P+ +++ Sbjct: 1094 EFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEK 1153 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 GS+ P P EW VN + ++ Sbjct: 1154 GSEAVFSAHAFGIPLPTYEWSVNGRKVR 1181 Score = 108 bits (260), Expect = 1e-21 Identities = 120/526 (22%), Positives = 205/526 (38%), Gaps = 39/526 (7%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E PP F K + + EG I EC + PEP++ WL + + P + + + Sbjct: 644 EAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRLQYDGQ-- 701 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIV 746 + L+I + + G YTV N G L ++ + P+ ++ + Sbjct: 702 --TAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVEC 759 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD--EGVYT 804 +GE V + + G+P P I W N KP+ I IL K V +G+ T Sbjct: 760 DEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVT 819 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 + N G A + V P PP F ++ TV+EK T+ V+ P P++ Sbjct: 820 CQGSNRLGSASCDGRLKVRVP----PAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTL 875 Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 T+ + + E + + + I N + G+ A N G + AR+T+ Sbjct: 876 TFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTV 935 Query: 924 DVEK------VTFVKHLQ-KSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREII 976 + E+ TF+K ++ ++ +T E + + W+ N ++ + Sbjct: 936 EQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMD-QGSPGVK 994 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV-----KETIPEFIRKLQDFE 1027 E G + C ++ ET LVV ++ P+F+ L D Sbjct: 995 IEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKT 1054 Query: 1028 VKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 + + EV + E V W GE +K E G I K+ I+N + D GE Sbjct: 1055 ETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSI-KISIKNIKIEDAGE 1113 Query: 1087 YSCILRD----ESCTAEVTVVELP--PEIITRLQNQKVNKGNKATF 1126 + + + A++TV + P PE R + V KG++A F Sbjct: 1114 IRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVF 1159 Score = 102 bits (244), Expect = 1e-19 Identities = 140/645 (21%), Positives = 259/645 (40%), Gaps = 55/645 (8%) Query: 1090 ILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGS 1144 + DES E+ P P+ IT++++ K KG+ A FE + TKG +W KDG Sbjct: 2867 LTEDESLREEMHRTPTPVMAPKFITKIKDTKAKKGHSAVFECVVPDTKG-VCCKWLKDGK 2925 Query: 1145 EIQFSNHIQL-TIDGKK----QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EEP 1194 EI+ I++ T G + Q+L + + +DAG+Y+C V G C A LTV E Sbjct: 2926 EIELIARIRVQTRTGPEGHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESL 2985 Query: 1195 SINFTLRLPEFILV----PANTDAYLTVE---IPDETLDVTW-YKKKSVIEDTEKFTLIS 1246 + PEFI+ T + +E I + V+W + K++ +++ + Sbjct: 2986 EKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVE 3045 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYEREYRIKRGSD 1304 V++ T+ + + Q +YTC+ + + T+K + + V P + + G Sbjct: 3046 GVERVTITSSELSH--QGKYTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEK 3103 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPS---IDSKSAS----LTIKKVENTDAG 1356 + L + PQP+ ++ S+ K + K T S I+ + + I ++ D Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 YK N+ G A +T + +P + + + E + G++ + + Sbjct: 3164 SYKAIATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222 Query: 1417 VEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 + + + +K +T ++ T + ++ A A N +++S E + Sbjct: 3223 KDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQ- 3281 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT------AKA 1527 ++ PT + L + NE L+ GVP P V W +DG+ ++T AK Sbjct: 3282 ----SLEKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKV 3337 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKV 1586 Y C A N GE +T + + V E + + K Sbjct: 3338 EGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKE 3397 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI--TTKEKTSVIRIKELKRSHSSKYT 1644 + ++ + G P P V W+K+ + D + I T + + I + ++ Y+ Sbjct: 3398 KESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYS 3457 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWK 1688 A N AG + + PE +R + RE T++ K Sbjct: 3458 CRARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLK 3502 Score = 97.1 bits (231), Expect = 5e-18 Identities = 113/461 (24%), Positives = 185/461 (40%), Gaps = 44/461 (9%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F + L K + STV FE V G+P P +T+ +K ++ D + Sbjct: 844 PTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYRIS 903 Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I + G A+N G A S L VE + S Sbjct: 904 IPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA------------------ 945 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 PTF K + Q V G + E + P P++ W G ++ D+ S ++ + Sbjct: 946 -----PTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM--DQG-SPGVKIEA 997 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 H + L I + + GT A N G E +V+ +K+PP+ +E L Sbjct: 998 HNHDHKLTIDSAQ--YAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTE 1055 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITI-LKPKKVKDEGVYT 804 +V+ +V G P+PT+TW + +K + SI I +K K++D G Sbjct: 1056 TVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A NSEG ET A +TV++ P F R +TV++ A P+P+ Sbjct: 1116 AVATNSEGSDETKAKLTVQK----KPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTY 1171 Query: 865 TWYRNNEIISPSET---ITQN---FDGENIELVIT-NVDSEIDSGDYKCVASNSAGKSSH 917 W N + + +T++ DG +I + T SE++ VA N+ G Sbjct: 1172 EWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEET 1231 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958 GA++TI+ +K + V Q +E K + + + + +T Sbjct: 1232 GAQLTIEPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272 Score = 96.7 bits (230), Expect = 6e-18 Identities = 146/708 (20%), Positives = 276/708 (38%), Gaps = 67/708 (9%) Query: 1046 DVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100 D+ W +D ++ + +++ + ++ G + I V D G Y+C+ +E S +A Sbjct: 578 DITWYKDDVQLHEDERHTFYSDEDGFFA-MTIDPVQVTDTGRYTCMATNEYGQASTSAFF 636 Query: 1101 TVVEL-----PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL 1154 V+++ PP +T+L++++ +G+ FE E+ + + W D ++ S+ +L Sbjct: 637 RVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHDFRL 696 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE-EPSINFTLRLPEFILVP 1209 DG+ KL+I D DD G Y+ ++ G+ + A L V+ +P N PEF Sbjct: 697 QYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVA--PEFQATI 754 Query: 1210 ANTDA-------YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 + + +V D ++ W+ + ++EK IS+ L I+ T Sbjct: 755 EYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHF 814 Query: 1263 QCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 TC L A +LKV V PP + ++ S V VD +P+P Sbjct: 815 DGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPT 874 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS---ASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 + + K +K + + S+ ++ D I + +N G A+ + Sbjct: 875 LTFTLCGKELKNGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVA-KAQNEHGTAESRARL 933 Query: 1376 TI-LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNI 1433 T+ ++ P L+ I D+ TG + V W I+ + Sbjct: 934 TVEQEEEESRSAPTFLK----DIE---DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKM 986 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETTEYYKVIKETKIQSPTVEK-PLK- 1489 + ++ N ++ + + A ++ + +P +K P K Sbjct: 987 DQGSPGVKIEAHNHDHKLTIDSAQYAGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKF 1046 Query: 1490 -NITTEPNEDIELTCIFG----GVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX 1540 I + E ++ T +F G P+P VTWY G++LK + ++ Sbjct: 1047 VEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNI 1106 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGI 1599 + +A N G ET + +Q+KP + + G E + +A GI Sbjct: 1107 KIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGI 1166 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--------TIEASNTA 1651 P P W NG K+ + +E T+++++V L ++ Y ++ A NT Sbjct: 1167 PLPTYEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTL 1226 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 G L + +P K V +++S V E + + E T Sbjct: 1227 GAEETGAQLTI--EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEAT 1272 Score = 90.6 bits (215), Expect = 4e-16 Identities = 86/357 (24%), Positives = 146/357 (40%), Gaps = 16/357 (4%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 G PTF+K + + + EG L++ +L + P+P I WL G EI D + + E D Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQ 748 + S+L+ K +G T+ A + G A L + G P + + + + Sbjct: 2520 LKLSILQ---TKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPAFQSDIAPINLTE 2576 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-- 806 G+++ + G+P P + W + V A + + + +K V + +K Sbjct: 2577 GDTLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKCV 2636 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N G T + V P P F + T +E T+KL A + P P ++W Sbjct: 2637 AYNKAGEVSTEGPLKVVAPI-----PVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSW 2691 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--D 924 Y N + + S+ I + + + I ++ + SG C A N GK++ A + + Sbjct: 2692 YVNGKKLEESQNIKIHSEKGTYTVTIKDITCDY-SGQVVCEAINEYGKATSEATLLVLPR 2750 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGR 980 E F++ L K V T S WY N KEI D I+ + + Sbjct: 2751 GEPPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDK 2807 Score = 88.6 bits (210), Expect = 2e-15 Identities = 75/271 (27%), Positives = 124/271 (45%), Gaps = 20/271 (7%) Query: 653 LECRLVAI--PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 LEC+L+ P P + W + + E+ ++ + ++ +KI V G Sbjct: 2580 LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVY----TMKIHGVTADMTGKIKC 2635 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 VA N+ GE S LK+ P + L R+G+++ L A ++G P P ++W Sbjct: 2636 VAYNKAGEVSTEGPLKVVA--PIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693 Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 N K ++ + S+ T+++TI K G +A N G A + A + V Sbjct: 2694 NGKKLEESQNIKIHSEKGTYTVTI-KDITCDYSGQVVCEAINEYGKATSEATLLVLP--- 2749 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARV--TRNPVPSITWYRNNEIISPSETITQNFDG 885 EPP F+ + + GT K+V +V T +P PS+TWY NN+ I S+ T D Sbjct: 2750 -RGEPPDFLEWLSNVRART-GT-KVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDD 2806 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + L I + + ++ G+ C A N AG+ S Sbjct: 2807 KTSTLTINSFNPDVHVGEIICKAENDAGEVS 2837 Score = 86.2 bits (204), Expect = 9e-15 Identities = 151/715 (21%), Positives = 276/715 (38%), Gaps = 68/715 (9%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+ KL+D E KE DV E E+ ++VW D + ++P + + + G KL Sbjct: 648 PAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSHD-FRLQYDGQTAKLE 706 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP------PEIITRLQNQKVNKGNKAT 1125 IR+ D G Y+ +++E AE+ V P PE ++ + ++G + Sbjct: 707 IRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVR 766 Query: 1126 FEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179 F+ +T GD + WF +G + S ++ + L I D G +C+ Sbjct: 767 FKSVIT-GDPNPEIIWFINGKPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNR 825 Query: 1180 VGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEI---PDETLDVTWYKKKSV 1235 +G++ C L V P T P E V + V++ P+ TL T K+ Sbjct: 826 LGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELK 885 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVE-----F 1286 + + D R I + E + A+S +L VE E Sbjct: 886 NGEEGVEIVGHDGFYRISIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSA 945 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASL 1345 P + D E + +K G + P P W +N K+ + K + L Sbjct: 946 PTFLKDIE-DQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHDHKL 1004 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-----DSSSINIC 1400 TI + AG R EN G + + + +L P +EI ++ + Sbjct: 1005 TIDSAQY--AGTVLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVV 1062 Query: 1401 WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458 ++ E T+ +Y+ + +E+ ++ + ++ + + SI+N+K + RA A N Sbjct: 1063 FEVRVEGEPKPTVTWYL-KGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATN- 1120 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 S+ S+ T+ K+ + K +P + ++T E + + G+P P W + Sbjct: 1121 ---SEGSDETKA-KLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVN 1176 Query: 1519 GKKLKT----AKATYENRXXXXXXXXXXXXXXXY--------KCIAFNDHGEVETSCVVG 1566 G+K++ A+ T + Y +A N G ET + Sbjct: 1177 GRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLT 1236 Query: 1567 IQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 I+ +K + + +D+ +V E + ++ P L + K ++T E Sbjct: 1237 IEPKKESVVVEKQDLSSS-EVQKE--IAQQVKEASPEATTTITMETSLTSTKTTTMSTTE 1293 Query: 1626 KTSVIR--IKELKRSHS-SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 TS + E K S S S T+ + G + +++ + SK + +RE Sbjct: 1294 VTSTVGGVTVETKESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVRE 1348 Score = 70.9 bits (166), Expect = 4e-10 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 7/190 (3%) Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 +Y E + + + P+PDI W F+G +I S + L IT K Sbjct: 6419 RYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSK 6478 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 G Y A N G+A I++ + T P I+PL + + + + +V G P Sbjct: 6479 ENVGQYQCFAKNDYGDAQQNIMVDLATR----PNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534 Query: 763 RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P + W K +P+ + DG I+ +D G+Y+ A N G A TS Sbjct: 6535 FPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCT 6594 Query: 820 ITVEEPTEEN 829 +TVE + N Sbjct: 6595 VTVEAEGDYN 6604 Score = 64.9 bits (151), Expect = 2e-08 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 +++ I+K+ +++ + APIF +LR + FEC V P P++TW Sbjct: 7504 ERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDF 7563 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 Q I++ S D D+NVA L++ P D G + C A N G S+ LI Sbjct: 7564 QGKILE-SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI 7616 Score = 60.5 bits (140), Expect = 5e-07 Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%) Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--- 1531 K+++ ++P L++ TT+ +E + L C G P+PKV+W D K + T E+ Sbjct: 2987 KKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEG 3046 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-KVGDE 1589 Y CIA N G +T + +Q + PV T ++++ K +G++ Sbjct: 3047 VERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPVFT---KELQNKELSIGEK 3103 Query: 1590 WLVTAVIEGIPPPEVIWY------KNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSS 1641 +++ ++G P P V +Y K K+ + I + + R I ++ + Sbjct: 3104 LVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIV 3163 Query: 1642 KYTIEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 Y A+N+ G TS+ ++T KV + P +G +E + +E K +E Sbjct: 3164 SYKAIATNSIGTATSTSKITTKV-EAPVFEQGLKKTSVKEKEEIKMEVKVGGSAPDVEWF 3222 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 K E N+ K + + V T +++ + A NP G +E+ Sbjct: 3223 KDDKPVSEDGNHEMKK--NPETGVFTLVVKQAATTDAGKYTAKASNPAGTAES 3273 Score = 57.6 bits (133), Expect = 4e-06 Identities = 42/149 (28%), Positives = 67/149 (44%), Gaps = 3/149 (2%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E+Q P FVE L K +TV FE +VEG P+P +TW+ + +K S ++ D Sbjct: 1038 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 1097 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXX 622 ++ + I+ + EDAG VA N+ G + +L V+ P + V Sbjct: 1098 SI-KISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSE 1156 Query: 623 XXXADILEGIP-PTFSKKPKAQYVDEGSD 650 + GIP PT+ + V +G + Sbjct: 1157 AVFSAHAFGIPLPTYEWSVNGRKVRDGQE 1185 Score = 57.6 bits (133), Expect = 4e-06 Identities = 36/107 (33%), Positives = 49/107 (45%), Gaps = 5/107 (4%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNV 565 S+ P F +KLRP + T+ + V G P P + WF+ I D+ Sbjct: 3479 SIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGH 3538 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV----EAPLSDHG 608 TL I++ ED G +TC A N AG A +T + V EAPL G Sbjct: 3539 HTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQG 3585 Score = 57.2 bits (132), Expect = 5e-06 Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 9/171 (5%) Query: 1507 GVPQPKVTWYRDGKKL-----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P +TWY+D +L T + + Y C+A N++G+ T Sbjct: 573 GYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQAST 632 Query: 1562 SC---VVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 S V+ ++++ ++ K K GD +EG P PE++W + L Sbjct: 633 SAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWLVDDQPLRPSH 692 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 ++ + +T+ + I++ + + YT++ N G+ + L V P K Sbjct: 693 DFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADPDK 743 Score = 56.4 bits (130), Expect = 8e-06 Identities = 46/203 (22%), Positives = 87/203 (42%), Gaps = 20/203 (9%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534 ++P + +PL+NI + L C F G P+P + W++DG+++ + + Sbjct: 5813 KAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIESPDGVCE 5872 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI---QQKP-VITISNEDIK--------- 1581 Y+C+A N +G TSC V + +KP I S + K Sbjct: 5873 LVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLT 5932 Query: 1582 -QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSH 1639 ++ K GD + G P P + W K+G +L +D++ + + T + + ++ Sbjct: 5933 IRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 5992 Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662 + A+N GT+S + L + Sbjct: 5993 EGYFRCVATNEHGTASTKAELVI 6015 Score = 55.6 bits (128), Expect = 1e-05 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 1/128 (0%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D YT +Q + K +F + ++ +AP F + +G V+F+ + G Sbjct: 714 DTGVYTVKIQNEFGSIESKAELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITG 773 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 P P+I WF + S+ + + +D + L I++V G TC N G AS Sbjct: 774 DPNPEIIWFINGKPLSESEKVK-FISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCD 832 Query: 596 TELIVEAP 603 L V P Sbjct: 833 GRLKVRVP 840 Score = 55.6 bits (128), Expect = 1e-05 Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 26/209 (12%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-----AKATYENRXX 1534 ++P PL +P + + C+ G P P + W +DG +L + +A + Sbjct: 5923 KAPGFTTPLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQR 5982 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSC--------VVGIQQKPVITISNEDIKQKHKV 1586 ++C+A N+HG T +G + P + E+ K + + Sbjct: 5983 LILSDVTFLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRR 6042 Query: 1587 G------DEWLVTAVI---EGIPPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIK 1633 G E V +I GIP P V WYK+G ++ D K T + + I Sbjct: 6043 GLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIV 6102 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +Y++EA+N G++ E +L + Sbjct: 6103 NASPDDEGEYSLEATNKLGSAKTEGSLNI 6131 Score = 53.6 bits (123), Expect = 6e-05 Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 13/185 (7%) Query: 748 QGESVILSAQVVGNPRPTITW------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801 + +++ + V G P P I W + P + G + + + ++ G Sbjct: 6423 ENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENVG 6482 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y A+N G A+ + I V+ T N PL +N+ T +++ RV P Sbjct: 6483 QYQCFAKNDYGDAQQN--IMVDLATRPNFIQPL-VNK----TFSSAQPMRMDVRVDGEPF 6535 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P + W + I S I DG + +I N DSG Y CVA N AG+++ V Sbjct: 6536 PELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSCTV 6595 Query: 922 TIDVE 926 T++ E Sbjct: 6596 TVEAE 6600 Score = 53.2 bits (122), Expect = 8e-05 Identities = 26/93 (27%), Positives = 49/93 (52%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F++ L K ++ + +V+G P P++ W ++ I S + D + +L+ Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 I + D+G ++CVA N AG A+++ + VEA Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQATTSCTVTVEA 6599 Score = 52.4 bits (120), Expect = 1e-04 Identities = 33/116 (28%), Positives = 61/116 (52%), Gaps = 9/116 (7%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW--FRQTAIIK----PSQDFQMY 559 Q AP+F ++L+ K G + C V+G P+P + + F +T ++ S + Sbjct: 3083 QGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIE 3142 Query: 560 YDDDNVA-TLVIREVFPEDAGTFTCVAKNAAGFASSTTELI--VEAPLSDHGSEMT 612 +D N +VI ++ ED ++ +A N+ G A+ST+++ VEAP+ + G + T Sbjct: 3143 HDQTNTHWRMVISQITKEDIVSYKAIATNSIGTATSTSKITTKVEAPVFEQGLKKT 3198 Score = 51.6 bits (118), Expect = 2e-04 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 4/112 (3%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 L V E + + AP F+ L+ K T V EC+V G P+P+++W I +Q Sbjct: 2979 LTVIESLEKKSEKKAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTI--TQ 3036 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPL 604 + + V + I G +TC+A+N G + + L V EAP+ Sbjct: 3037 ESITVESVEGVERVTITSSELSHQGKYTCIAENTEGTSKTEAFLTVQGEAPV 3088 Score = 50.0 bits (114), Expect = 7e-04 Identities = 23/71 (32%), Positives = 36/71 (50%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S+ + +V GYP P ITW++ + + Y D+D + I V D G +TC+ Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622 Query: 585 AKNAAGFASST 595 A N G AS++ Sbjct: 623 ATNEYGQASTS 633 Score = 50.0 bits (114), Expect = 7e-04 Identities = 49/235 (20%), Positives = 88/235 (37%), Gaps = 12/235 (5%) Query: 1466 ETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 ET KV++ K + P L+++ + +++ I + P WY++G L+ Sbjct: 1965 ETKTELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMDVI--ALHSPLYKWYQNGNLLED 2022 Query: 1525 AK--ATYENRXXXXXXXXXXXXXXXYKCI-AFNDHGEVETSCVVGIQQK---PVITISNE 1578 K T +N + A N+ G E+S + + P++ + Sbjct: 2023 GKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPK 2082 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 + K E+ T I G P P V W N +E + E ++I K Sbjct: 2083 SVTIKETETAEFKAT--ISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIE 2140 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISRESVTIEWKPPLD 1692 + + A N+AG S + LKV P+ + +++ E + W LD Sbjct: 2141 QTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNLELD 2195 Score = 50.0 bits (114), Expect = 7e-04 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 6/135 (4%) Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAE---PPLFINRFQEITVKE 846 L+PK + KA ++ I A I P T++N + P+F R +++ +++ Sbjct: 7482 LEPKSHEQSTALLQKAPSATAIERIKADIEKVTPCATKKNDDGTFAPIFTARLRDVYLRK 7541 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 V+ +P P +TW +I+ ++ +T D N+ +I N + D G+Y C Sbjct: 7542 NQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQD-NNVARLILNHAAPYDLGEYVC 7600 Query: 907 VASNSAGKSSHGARV 921 A N G R+ Sbjct: 7601 TAINEYGTDKSSCRL 7615 Score = 48.8 bits (111), Expect = 0.002 Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 8/169 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + P P+V W G LE++ I + + + +Y A N GT Sbjct: 7551 VSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDK 7610 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNN--- 1711 L + PS+P P E+S ++ + I+W+ P LE Y +E N Sbjct: 7611 SSCRLISGETPSRPGRP--EAELSSDTEIFIQWEAPEGPTYLEGITYRLEYRVAGPNDHG 7668 Query: 1712 -RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 WI V++ D E+ ++ L+ Y FRV AQN G S IV Sbjct: 7669 DPWITVSE-KIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLSSRIV 7716 Score = 48.0 bits (109), Expect = 0.003 Identities = 59/231 (25%), Positives = 94/231 (40%), Gaps = 28/231 (12%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIK---PKKNKYDFEKR 1068 +E P R L + + E +V + V T V W +DG+ I P + F Sbjct: 6034 EECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDE 6093 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE--------------LPPEII 1110 I L I N S DEGEYS ++ +A+ + ++ PP + Sbjct: 6094 RGIHHLVIVNASPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFV 6153 Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQL-TIDGKKQKLKIYDC 1168 +L+N+ V F+ + A V WF +G +I I++ + G L I D Sbjct: 6154 RQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDT 6213 Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 L+DAGEY G++ +A+L V P ++ E + P T+ Y Sbjct: 6214 TLEDAGEYVATAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEY 6264 Score = 47.2 bits (107), Expect = 0.005 Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 5/177 (2%) Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 F P R+ +++ A P P W KI++ D+ A L Sbjct: 7526 FAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARL 7585 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 + D G Y N G + + PS PG+P + I I W+ PE Sbjct: 7586 ILNHAAPYDLGEYVCTAINEYGTDKSSCRLISGETPSRPGRPEAELSSDTEIFIQWEAPE 7645 Query: 1406 NTGNSTIIYYVVEYQEIDTTE----WISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457 I Y +EY+ + WI+V + I +++L Y+FR A N Sbjct: 7646 GPTYLEGITYRLEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQN 7702 Score = 43.6 bits (98), Expect = 0.061 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 1381 PSPPGK-PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVK-NITKTQ 1437 P+PP + P I E+ + + W + + YV+E +E+ +W ++ NI + Sbjct: 6275 PTPPDRGPFIKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPV 6334 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 ++NL+ SY+FR A N ISD S Sbjct: 6335 CKVRNLELGKSYQFRVRAENIYGISDPS 6362 Score = 40.7 bits (91), Expect = 0.43 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+ + + Y+ + + EC + A P P + W F+G+ + + N V IE D ++ + Sbjct: 7528 PIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGK--ILESNDRVTIEQDNNV--A 7583 Query: 694 VLKITNVKKFQEGTYTVVAVNREG 717 L + + + G Y A+N G Sbjct: 7584 RLILNHAAPYDLGEYVCTAINEYG 7607 Score = 39.1 bits (87), Expect = 1.3 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Query: 503 SEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITW-FRQTAI--IKPSQDFQM 558 SE+ + AP F + K + + T+ V G+P P I W FR I P+ ++ Sbjct: 6402 SEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKV 6461 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 Y + TL I E+ G + C AKN G A Sbjct: 6462 YTYGGSETTLAITGFSKENVGQYQCFAKNDYGDA 6495 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 416 EVRCGDTVFAVYSYVAETD--EAINLVEGERLYILDTSNQDWWYVQ-KHLTEEKGWVPAQ 472 E R A+ Y + + EAI L +G+ + +LD N W V+ K GWVP Sbjct: 61 ESRSYPVYIAIQDYTPDKEDVEAIPLEQGQIVEVLDKKNSVRWLVRTKARPPRSGWVPGS 120 Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEK 500 Y + Y Q++ +I+ + + ++ Sbjct: 121 YFETPTEF--YKQRRRTREIENVSLSDE 146 Score = 36.3 bits (80), Expect = 9.2 Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 1/84 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P++ WYK+ +L D+ + + E + I ++ + + +YT A+N G + Sbjct: 571 VTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMATNEYGQA 630 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678 S +V + P + ++ Sbjct: 631 STSAFFRVLKVEKEAAPPAFVTKL 654 >UniRef50_UPI0000E460FC Cluster: PREDICTED: similar to Bent, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Bent, partial - Strongylocentrotus purpuratus Length = 1581 Score = 256 bits (626), Expect = 6e-66 Identities = 186/740 (25%), Positives = 312/740 (42%), Gaps = 39/740 (5%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 D R+ +IK G + L V ++A P P W +N + H + + + +K + Sbjct: 244 DKLRDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMAD 303 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNS 1410 +D G Y+L+L N+ G NV + D+PSPP P I ++ + ++ W PE+ G S Sbjct: 304 KSDTGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSLAWQAPEDDGGS 363 Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I+ Y++E E D W V + + L ++Y+FR A N + +E Sbjct: 364 DILNYIIEKSEGDDDYWSKVTGFCQDPKGVATKLNQGTNYKFRVRAENSAGFTSEPLESE 423 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTA 1525 K K + + KP + D+E T K++ Y R+ + + Sbjct: 424 MVKA-KNPYEAASSPGKPSIPTYDKTTADLEWTA-SSSDGGDKISGYIVERRESRSSRWV 481 Query: 1526 KATYENRXXXXXXXXXXXXXXXY--KCIAFNDHG------EVETSCVVGIQQKPVITISN 1577 KAT E Y + A N G E + + P I S Sbjct: 482 KATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSG 541 Query: 1578 EDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 + + K G + + G P P V W K+ +++ + + T E S + + Sbjct: 542 FGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAE 601 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 R Y I+ N+ G+ S + + V D+P+ P GP+ E ++ESV + WK P DG Sbjct: 602 RGDQGSYMIKLDNSRGSDSYSLNVLVLDRPTAPGGPIEYSEFTKESVRLTWKAPEQDGNS 661 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALES 1755 ++ Y++E+ +P + W +V T C+ K L +Y+FR+ A N G SE LE Sbjct: 662 SVSGYSVERRDPKKDFWTRV--TSNAPTTSCVVKDLVYQNDYVFRICAINQYGTSEPLEG 719 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWK 1814 + +K D P + S ++W P + +GGSP+ Y VE + ++W+ Sbjct: 720 RQVKVKLPFDEPD-APSAPKIDAMSRISADLSWAPPDHDGGSPVTGYLVEFHPTDAREWQ 778 Query: 1815 XXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 + L T YQFR+ A N+ G P S + + + P P Sbjct: 779 RANSFPIRDTVYTVPNLREGTEYQFRVIAANDAGEGKPSRSSESVVAKDPILPADAPGRP 838 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSVHEHCIE 1928 + + T S + W++P S+GG+PI Y IE + KG WT + V + Sbjct: 839 TLEKVTKDSAAISWSKPVSDGGAPIKGYTIEKRKAGPGPKG-DWTPCLEVSPKEESAVVP 897 Query: 1929 NIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLE-IRMVGS-----N 1981 ++ E +E+ FR+ A N P+ + + +E P LE I++ G N Sbjct: 898 DLVEGEELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEIN 957 Query: 1982 IVMTSWGTP--EWD-GGAPL 1998 + +T + TP W+ G +P+ Sbjct: 958 LPLTGFPTPTATWELGSSPV 977 Score = 238 bits (583), Expect = 1e-60 Identities = 169/639 (26%), Positives = 274/639 (42%), Gaps = 25/639 (3%) Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + ++K G + + FP P W + S +K+ + L + E DA Sbjct: 945 DIKVKGGEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDA 1004 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 G Y + ++N+ G + VT++ +P P G + +I +S+ + W +P N G + Sbjct: 1005 GRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVTLSWKQPVN-GPEDVEN 1063 Query: 1415 YVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 YVVE ++ DT W V + + ++NLK Y+FR A N+ +S T+E + Sbjct: 1064 YVVEKRDPDTGAWSKVSSFVPSPHFKVKNLKEGGEYQFRVSAENQYGVSKPI-TSE--TI 1120 Query: 1474 IKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKAT 1528 I + P + +P TT I+ T P V + + +K TA Sbjct: 1121 IAKNPFDPPGMPSQPEVTTTTSTTISIQWTRPSNDGGNPIVGYTVEKRKEHGDWSTATRA 1180 Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VETSCVVGIQQKPV---ITISNEDIKQ 1582 ++ A N+ G ++S + + PV + S+ + + Sbjct: 1181 PVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPSDSSDAITARPPPVKPKVDSSSRNREV 1240 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWY---KNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 G+++ V EG PPP + W KNG +E E +S++ E +R Sbjct: 1241 TAVAGEKFRVEISFEGSPPPNITWSRSDKNGITVEPSNRIAFEDTELSSIMANSEAERGD 1300 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 + Y + SN GT + V + V DKPS PEGP+ +++ + + WKPP DDGG +T Sbjct: 1301 AGTYAVTFSNEKGTDTATVRIIVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVT 1360 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758 Y IEK + W KV+ R TY + L+E FRV A+N G LE S+ I Sbjct: 1361 NYVIEKQAAGRSAWTKVSTYVR-TTTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAI 1419 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW--KXX 1816 IK D P +D V ++W E +GGSPII Y VE ++ +W Sbjct: 1420 TIKDPFDAPE-APGKPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERDGEWIPVND 1478 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 + L Y+FR++A+N+ G + I + PS P V S+ Sbjct: 1479 YNVKETTLPVGNLRDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPSAPGVPVASD 1538 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 +V L+W +P S+GGS + Y++E + W + Sbjct: 1539 IGRDTVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPV 1577 Score = 226 bits (553), Expect = 5e-57 Identities = 184/740 (24%), Positives = 313/740 (42%), Gaps = 32/740 (4%) Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTI 1412 D+G Y + ++N G VT++DK S P P I +I S + + W+ PE+ G + Sbjct: 10 DSGGYTVTVQNAHGTETATAQVTVIDKSSAPKAPLEITDIFSEYLTLTWNAPEDDGGLPL 69 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 Y+VE +++ + W + + TK T + L + Y FR A N +S E ++ Sbjct: 70 SNYIVERRDVRRSGWSVINDTTKDTTMKVTRLVEGTEYMFRVAAENSEGVSKWLEASK-- 127 Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVP-QPKVTWYRDGKKLKTAK 1526 V+ + P + + + +EL GG P + V R+ + + Sbjct: 128 SVVAKNPYDEPG-SPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQE 186 Query: 1527 ATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQKPVI---TISNEDI 1580 T ++ A N G + S C + KP T+ + + Sbjct: 187 VTTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECSAPQKTKPKFARPTLKGDKL 246 Query: 1581 KQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 + K K G E++++ + E P PE+ W NGNK+ + +E+ + +++K +S Sbjct: 247 RDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKSD 306 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 + Y ++ +N +G + V D+PS P GP+ + ++ + ++ W+ P DDGG ++ Sbjct: 307 TGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSLAWQAPEDDGGSDIL 366 Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF-SEALESEPI 1758 Y IEK E D++ W KV +D + KLN+ Y FRV A+N GF SE LESE + Sbjct: 367 NYIIEKSEGDDDYWSKVTGFCQDPKGVA-TKLNQGTNYKFRVRAENSAGFTSEPLESEMV 425 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXX 1816 K + S D + + W S +GG I Y VE ++ +W K Sbjct: 426 KAKNPYEAAS-SPGKPSIPTYDKTTADLEWTASSSDGGDKISGYIVERRESRSSRWVKAT 484 Query: 1817 XXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPY-TSDDKITIGKTLTPPSQPRNFVV 1874 A + L Y FR++A N G S P SD + + P F + Sbjct: 485 REPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSGFGL 544 Query: 1875 SESTSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 + ++ P +P ++ + K +K + T + C + Sbjct: 545 GDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLC-SFAERG 603 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 D+ + I +N+ G ++S S+ + P+ P P+E V +W PE D Sbjct: 604 DQGSYMIKLDNSRG----SDSYSLNV-LVLDRPTAPGGPIEYSEFTKESVRLTWKAPEQD 658 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 G + + GY++ RD K W V + T ++DL + Y+ RI A N+ G SEPL Sbjct: 659 GNSSVSGYSVERRDPKKDFWTRVTS-NAPTTSCVVKDLVYQNDYVFRICAINQYGTSEPL 717 Query: 2054 ESDEPFKVIPGEGSHADEEP 2073 E + +P + A P Sbjct: 718 EGRQVKVKLPFDEPDAPSAP 737 Score = 192 bits (468), Expect = 9e-47 Identities = 142/518 (27%), Positives = 233/518 (44%), Gaps = 29/518 (5%) Query: 1569 QKPVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 ++P + I + EDIK K G+++ + + G P P W + ++ +TT Sbjct: 934 ERPKLDIGSLEDIKVKG--GEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTARTY 991 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 + +++ +R + +YTI N +G+ + V + V +P P+GPV + +IS SVT+ W Sbjct: 992 TKLKVDSAERQDAGRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVTLSW 1051 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 K P+ +G ++ Y +EK +PD W KV+ + ++ L E EY FRV A+N Sbjct: 1052 KQPV-NGPEDVENYVVEKRDPDTGAWSKVSSFVPSPH-FKVKNLKEGGEYQFRVSAENQY 1109 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G S+ + SE I+ K D P + ++ I W +GG+PI+ Y VE + Sbjct: 1110 GVSKPITSETIIAKNPFDPPGMPSQPEVTTT-TSTTISIQWTRPSNDGGNPIVGYTVEKR 1168 Query: 1808 QEGKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 +E W KL+ T+Y+FR+ A NE G P S D IT P Sbjct: 1169 KEHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPSDSSDAIT---ARPP 1225 Query: 1866 PSQPRNFVVSESTSRSVTL----KWTEPESNGGSPITNYIIEFKTVKG---KSWTKIVTV 1918 P +P+ V S S +R VT K+ S GSP N G + +I Sbjct: 1226 PVKPK--VDSSSRNREVTAVAGEKFRVEISFEGSPPPNITWSRSDKNGITVEPSNRIAFE 1283 Query: 1919 GGSVHEHCIENIKEK-DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 + + E+ D + ++ N G T++ +VR+ PS P PL Sbjct: 1284 DTELSSIMANSEAERGDAGTYAVTFSNEKG----TDTATVRIIV-VDKPSAPEGPLAATD 1338 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 V ++ SW P+ DGG+ + Y I + ++ W +V V T +++ +L E Sbjct: 1339 VTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTY-VRTTTYDVVNLDEGSVL 1397 Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075 R+ A N+ G+ PLE + + + A E PG+ Sbjct: 1398 KFRVSAENQHGVGPPLEGSQAITI--KDPFDAPEAPGK 1433 Score = 168 bits (408), Expect = 2e-39 Identities = 163/728 (22%), Positives = 291/728 (39%), Gaps = 43/728 (5%) Query: 1358 YKLRLENNCGHADVEMNVTILDKPSP------PGKPNILEIDSSSINICWDEPENTGNST 1411 +++R EN+ G + ++ +P PGKP+I D ++ ++ W + G Sbjct: 405 FRVRAENSAGFTSEPLESEMVKAKNPYEAASSPGKPSIPTYDKTTADLEWTASSSDGGDK 464 Query: 1412 IIYYVVEYQEIDTTEWI-SVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I Y+VE +E ++ W+ + + KT ++ NL Y FR +A N +S S ++ Sbjct: 465 ISGYIVERRESRSSRWVKATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESD 524 Query: 1470 YYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 ++ + + + ++P ++ L ++ + ++ F G P P V W +D K++K + Sbjct: 525 HH--VAKAQFEAPKIDTSGFGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSD 582 Query: 1527 A----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582 T E+ Y N G S V + +P + + Sbjct: 583 RFTVDTTESNSTLLCSFAERGDQGSYMIKLDNSRGSDSYSLNVLVLDRPTAPGGPIEYSE 642 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHS 1640 K L E V Y + + + K++ +T+ T+ +K+L + Sbjct: 643 FTKESVR-LTWKAPEQDGNSSVSGY-SVERRDPKKDFWTRVTSNAPTTSCVVKDLVYQND 700 Query: 1641 SKYTIEASNTAGTSSV----EVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 + I A N GTS +V +K+ +D+P P P I +SR S + W PP DGG Sbjct: 701 YVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAPKI-DAMSRISADLSWAPPDHDGG 759 Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALE 1754 +T Y +E H D W + Y + L E EY FRVIA N G + + Sbjct: 760 SPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIAANDAGEGKPSRS 819 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--- 1811 SE +V K + +P+ + +S I+W +GG+PI Y +E ++ G Sbjct: 820 SESVVAKDPI-LPADAPGRPTLEKVTKDSAAISWSKPVSDGGAPIKGYTIEKRKAGPGPK 878 Query: 1812 -KWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868 W A + L +FR+ A N+ P I P Sbjct: 879 GDWTPCLEVSPKEESAVVPDLVEGEELEFRVRANNDECPGKPSAPTPATVIEDKPERPKL 938 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 + + P + +P + + VK +S +VT + + ++ Sbjct: 939 DIGSLEDIKVKGGEKFEINLPLTGFPTPTATWELGSSPVK-ESGRVLVTTARTYTKLKVD 997 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988 + + +D + I+ +N G +V E P P P+++ + N V SW Sbjct: 998 SAERQDAGRYTITVKNDSGSDTARVKVTVIAE-----PDVPQGPVQVSDISPNSVTLSWK 1052 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P +G + Y + RD W +V V + F +++L E Y R+ A N+ G Sbjct: 1053 QPV-NGPEDVENYVVEKRDPDTGAWSKVSSF-VPSPHFKVKNLKEGGEYQFRVSAENQYG 1110 Query: 2049 LSEPLESD 2056 +S+P+ S+ Sbjct: 1111 VSKPITSE 1118 Score = 161 bits (392), Expect = 1e-37 Identities = 130/453 (28%), Positives = 202/453 (44%), Gaps = 28/453 (6%) Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 R+ S YT+ N GT + + V DK S P+ P+ + +I E +T+ W P DDGGL Sbjct: 8 RADSGGYTVTVQNAHGTETATAQVTVIDKSSAPKAPLEITDIFSEYLTLTWNAPEDDGGL 67 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755 L+ Y +E+ + + W + D +D T + +L E EYMFRV A+N G S+ LE S Sbjct: 68 PLSNYIVERRDVRRSGWSVINDTTKDT-TMKVTRLVEGTEYMFRVAAENSEGVSKWLEAS 126 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814 + +V K D P D + V + W +K+GG+PI Y VE ++ G +W+ Sbjct: 127 KSVVAKNPYDEPG-SPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQ 185 Query: 1815 XXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 ++ L +N +FR+ A N+ GT P T P R Sbjct: 186 EVTTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECS-----APQKTKPKFARPT 240 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIK 1931 + + R + +K G + + I E SWT V GS H ++N + Sbjct: 241 LKGDKL-RDIKIK------AGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVG-LKNEE 292 Query: 1932 EKDEIIFRISAENTVG---VSLPTESQSVRLEKHATV---PSPPTAPLEIRMVGSNIVMT 1985 E E+ +++ ++ G + L +S V+ + V PSPP P+EI V ++ Sbjct: 293 ELTEVKVKMADKSDTGTYELKLTNDSGDVKTSCNVIVQDRPSPPRGPIEISDVFADKCSL 352 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 +W PE DGG+ +L Y I + W +V K L++ Y R+ A N Sbjct: 353 AWQAPEDDGGSDILNYIIEKSEGDDDYWSKVTGF-CQDPKGVATKLNQGTNYKFRVRAEN 411 Query: 2046 EIGL-SEPLESDEPFKVIPGEGSHADEEPGEQT 2077 G SEPLES+ P E + + +P T Sbjct: 412 SAGFTSEPLESEMVKAKNPYEAASSPGKPSIPT 444 Score = 156 bits (378), Expect = 7e-36 Identities = 186/791 (23%), Positives = 313/791 (39%), Gaps = 85/791 (10%) Query: 1302 GSDVT-LLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 GS VT LV++ P EW NS I+ +T P++ + + + DAG K Sbjct: 759 GSPVTGYLVEFH--PTDAREWQRANSFPIRDTVYTVPNL-REGTEYQFRVIAANDAGEGK 815 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + V IL +P G+P + ++ S I W +P + G + I Y +E Sbjct: 816 PSRSSE----SVVAKDPILPADAP-GRPTLEKVTKDSAAISWSKPVSDGGAPIKGYTIEK 870 Query: 1420 QEIDTT---EWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 ++ +W ++ + S + +L FR A N+ S T + Sbjct: 871 RKAGPGPKGDWTPCLEVSPKEESAVVPDLVEGEELEFRVRANNDECPGKPSAPTP--ATV 928 Query: 1475 KETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWY-------RDGKKLKTAK 1526 E K + P ++ L++I + E E+ G P P TW G+ L T Sbjct: 929 IEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTGFPTPTATWELGSSPVKESGRVLVTTA 988 Query: 1527 ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV--GIQQKPV----ITISNED 1579 TY + K + +D V+ + + + Q PV I+ ++ Sbjct: 989 RTYTKLKVDSAERQDAGRYTITVKNDSGSDTARVKVTVIAEPDVPQGPVQVSDISPNSVT 1048 Query: 1580 IKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 + K V G E + V+E P W K +++ + ++K LK Sbjct: 1049 LSWKQPVNGPEDVENYVVEKRDPDTGAWSK------------VSSFVPSPHFKVKNLKEG 1096 Query: 1639 HSSKYTIEASNTAG-----TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 ++ + A N G TS + +D P P P + S +++I+W P +D Sbjct: 1097 GEYQFRVSAENQYGVSKPITSETIIAKNPFDPPGMPSQPEVTTTTST-TISIQWTRPSND 1155 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG----- 1748 GG + Y +EK + ++ W ++ KL E Y FRV A N G Sbjct: 1156 GGNPIVGYTVEKRK-EHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVKAVNEAGPGKPS 1214 Query: 1749 -FSEALESEPIVIKTALDVPSXXXXXXXXXX------IDNESV---YITWFPSEKNGGSP 1798 S+A+ + P +K +D S I E ITW S+KNG + Sbjct: 1215 DSSDAITARPPPVKPKVDSSSRNREVTAVAGEKFRVEISFEGSPPPNITWSRSDKNGITV 1274 Query: 1799 IIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 ++ + + ++ T + + NE GT T+ +I Sbjct: 1275 EPSNRIAFED------TELSSIMANSEAERGDAGT---YAVTFSNEKGTD---TATVRII 1322 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 + + P P ++ T+ L W P+ +GGS +TNY+IE + +WTK+ T Sbjct: 1323 VVDKPSAPEGP--LAATDVTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTY 1380 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977 + + + N+ E + FR+SAEN GV P E SQ++ ++ P P P Sbjct: 1381 VRTT-TYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAITIKDPFDAPEAPGKP-NADE 1438 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 V V SW PE DGG+P++GY + R+ W+ V +V + +L + Y Sbjct: 1439 VDRGFVRLSWEAPEADGGSPIIGYIVEKRE-RDGEWIPVNDYNVKETTLPVGNLRDTAEY 1497 Query: 2038 MIRIYARNEIG 2048 R++A+N+ G Sbjct: 1498 EFRVFAKNKAG 1508 Score = 136 bits (328), Expect = 8e-30 Identities = 111/474 (23%), Positives = 210/474 (44%), Gaps = 29/474 (6%) Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNV 1375 P +IV + +++ + + +K ++ + ++ ++++ EN+ G + +E + Sbjct: 68 PLSNYIVERRDVRRSGWSVINDTTKDTTMKVTRLVEGTEYMFRVAAENSEGVSKWLEASK 127 Query: 1376 TIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--I 1428 +++ D+P PG P +++ D + + W +P+ G + I YVVE +E+ +T W + Sbjct: 128 SVVAKNPYDEPGSPGVPAVVDFDRDFVELEWAKPKKDGGAPIEGYVVEKREVGSTRWQEV 187 Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KP 1487 + + T+ + NL N FR AVN+ SE + K + K PT++ Sbjct: 188 TTSPVKGTKYKVDNLPVNKELEFRVAAVNKAGTGKPSECSAPQKT--KPKFARPTLKGDK 245 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXX 1543 L++I + ++ L+ IF P P+++W +G K+ E Sbjct: 246 LRDIKIKAGQEFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKS 305 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW-LVTAVIEGIPPP 1602 Y+ ND G+V+TSC V +Q +P + I+ D+ L E Sbjct: 306 DTGTYELKLTNDSGDVKTSCNVIVQDRP--SPPRGPIEISDVFADKCSLAWQAPEDDGGS 363 Query: 1603 EVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 +++ Y K E D +Y +T + +L + + K+ + A N+AG +S + Sbjct: 364 DILNYII-EKSEGDDDYWSKVTGFCQDPKGVATKLNQGTNYKFRVRAENSAGFTSEPLES 422 Query: 1661 KV------YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 ++ Y+ S P P I + + +EW DGG +++ Y +E+ E ++RW+ Sbjct: 423 EMVKAKNPYEAASSPGKPSI-PTYDKTTADLEWTASSSDGGDKISGYIVERRESRSSRWV 481 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767 K Y + L EY+FRV A+N G S + ES+ V K + P Sbjct: 482 KATREPVKTLAYTVTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAP 535 Score = 116 bits (278), Expect = 9e-24 Identities = 137/620 (22%), Positives = 232/620 (37%), Gaps = 47/620 (7%) Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281 T TW S ++++ + + + L + D YT + + T ++KV Sbjct: 965 TPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDAGRYTITVKNDSGSDTARVKV 1024 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 V+ P + I S P+ + ++V + +K S Sbjct: 1025 TVIAEPDVPQGPVQVSDISPNSVTLSWKQPVNGPEDVENYVVEKRDPDTGAWSKVSSFVP 1084 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-----DKPSPPGKPNILEIDSSS 1396 S +K ++ +++ EN G + + TI+ D P P +P + S++ Sbjct: 1085 SPHFKVKNLKEGGEYQFRVSAENQYGVSKPITSETIIAKNPFDPPGMPSQPEVTTTTSTT 1144 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAY 1454 I+I W P N G + I+ Y VE ++ + +W + TS L +SY FR Sbjct: 1145 ISIQWTRPSNDGGNPIVGYTVEKRK-EHGDWSTATRAPVKDTSFTAFKLTEGTSYEFRVK 1203 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPK 1512 AVNE S++++ + P V+ +N +T E + F G P P Sbjct: 1204 AVNEAGPGKPSDSSD--AITARPPPVKPKVDSSSRNREVTAVAGEKFRVEISFEGSPPPN 1261 Query: 1513 VTWYRDGKKLKTA----KATYENRXXXXXXXXXXX---XXXXYKCIAFNDHGEVETSCVV 1565 +TW R K T + +E+ Y N+ G + + Sbjct: 1262 ITWSRSDKNGITVEPSNRIAFEDTELSSIMANSEAERGDAGTYAVTFSNEKGTDTATVRI 1321 Query: 1566 GIQQKPVI---TISNEDI---------KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 + KP ++ D+ K G + VIE W K + Sbjct: 1322 IVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVTNYVIEKQAAGRSAWTKVSTYV 1381 Query: 1614 ENDKEYNITTKEKTSVIRIK-ELKRSHSSKYTIEASNTAGTSSVEVTLK-VYDKPSKPEG 1671 Y++ ++ SV++ + + H +E S +T+K +D P P G Sbjct: 1382 RT-TTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQA-------ITIKDPFDAPEAP-G 1432 Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731 E+ R V + W+ P DGG + Y +EK E D WI V D + T + L Sbjct: 1433 KPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERD-GEWIPVNDYNVKETTLPVGNL 1491 Query: 1732 NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 + EY FRV A+N G A + I K ++ PS I ++V + W Sbjct: 1492 RDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPS-APGVPVASDIGRDTVDLQWDK 1550 Query: 1791 SEKNGGSPIIDYKVEIKQEG 1810 +GGS + Y VE ++EG Sbjct: 1551 PSSDGGSKLAGYVVEKREEG 1570 Score = 101 bits (243), Expect = 2e-19 Identities = 60/214 (28%), Positives = 96/214 (44%), Gaps = 6/214 (2%) Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 T P P + SE T SV L W PE +G S ++ Y +E + K WT+ VT Sbjct: 632 TAPGGPIEY--SEFTKESVRLTWKAPEQDGNSSVSGYSVERRDPKKDFWTR-VTSNAPTT 688 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 ++++ +++ +FRI A N G S P E + V+++ P P+AP +I + Sbjct: 689 SCVVKDLVYQNDYVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAP-KIDAMSRISA 747 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 SW P+ DGG+P+ GY + W + + + +L E Y R+ A Sbjct: 748 DLSWAPPDHDGGSPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIA 807 Query: 2044 RNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQT 2077 N+ G +P S E V+ + + PG T Sbjct: 808 ANDAGEGKPSRSSE--SVVAKDPILPADAPGRPT 839 Score = 101 bits (242), Expect = 2e-19 Identities = 72/277 (25%), Positives = 114/277 (41%), Gaps = 8/277 (2%) Query: 1747 VGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 V FS ++ ++ +D PS + + ++W P + +GGS + +Y +E Sbjct: 1306 VTFSNEKGTDTATVRIIVVDKPSAPEGPLAATDVTADFCRLSWKPPQDDGGSRVTNYVIE 1365 Query: 1806 IKQEGKK-W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 + G+ W K + L + +FR+ A N+ G P ITI Sbjct: 1366 KQAAGRSAWTKVSTYVRTTTYDVVNLDEGSVLKFRVSAENQHGVGPPLEGSQAITIKDPF 1425 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 P P E V L W PE++GGSPI YI+E + G+ W + Sbjct: 1426 DAPEAPGKPNADEVDRGFVRLSWEAPEADGGSPIIGYIVEKRERDGE-WIPVNDYNVKET 1484 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV--PSPPTAPLEIRMVGSN 1981 + N+++ E FR+ A+N G P + +E A + PS P P+ +G + Sbjct: 1485 TLPVGNLRDTAEYEFRVFAKNKAGKG-PASRTLLGIEPKAIINAPSAPGVPVASD-IGRD 1542 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 V W P DGG+ L GY + R+ W V K Sbjct: 1543 TVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPVSK 1579 Score = 65.3 bits (152), Expect = 2e-08 Identities = 61/279 (21%), Positives = 118/279 (42%), Gaps = 16/279 (5%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 V W K ++ +++FT+ + TL+ DQ Y L +++ + + V+ Sbjct: 569 VEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAERGDQGSYMIKLDNSRGSDSYSLNVLVL 628 Query: 1287 P-PKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 P EY K +T Q + V + KK T+ + ++ + Sbjct: 629 DRPTAPGGPIEYSEFTKESVRLTWKAPEQDGNSSVSGYSVERRDPKKDFWTRVTSNAPTT 688 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADV----EMNVTI-LDKPSPPGKPNILEIDSSSIN 1398 S +K + + ++++ N G ++ ++ V + D+P P P I + S + Sbjct: 689 SCVVKDLVYQNDYVFRICAINQYGTSEPLEGRQVKVKLPFDEPDAPSAPKIDAMSRISAD 748 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAV 1456 + W P++ G S + Y+VE+ D EW + I T ++ NL+ + Y+FR A Sbjct: 749 LSWAPPDHDGGSPVTGYLVEFHPTDAREWQRANSFPIRDTVYTVPNLREGTEYQFRVIAA 808 Query: 1457 NEVDISDASETTEYYKVIKETKIQS-----PTVEKPLKN 1490 N+ S ++E V K+ + + PT+EK K+ Sbjct: 809 NDAGEGKPSRSSESV-VAKDPILPADAPGRPTLEKVTKD 846 Score = 48.4 bits (110), Expect = 0.002 Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 11/106 (10%) Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL------KVYDKPSKPEG 1671 +YN+ K + + + L+ + ++ + A N AG TL + + PS P Sbjct: 1478 DYNV----KETTLPVGNLRDTAEYEFRVFAKNKAGKGPASRTLLGIEPKAIINAPSAPGV 1533 Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 PV +I R++V ++W P DGG +L Y +EK E + W V+ Sbjct: 1534 PVAS-DIGRDTVDLQWDKPSSDGGSKLAGYVVEKREEGSPDWEPVS 1578 Score = 46.4 bits (105), Expect = 0.009 Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 9/136 (6%) Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 K+ N+ +E + V AVN+ G E S P K K P + L+ + ++ G+ Sbjct: 198 KVDNLPVNKELEFRVAAVNKAGTGKPSECSAP--QKTKPKFARPTLKGDKLRDIKIKAGQ 255 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808 +LS P P I+W N V + +T +K K D G Y LK Sbjct: 256 EFVLSVIFEAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKSDTGTYELKLT 315 Query: 809 NSEGIAETSAVITVEE 824 N G +TS + V++ Sbjct: 316 NDSGDVKTSCNVIVQD 331 Score = 41.9 bits (94), Expect = 0.19 Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 10/157 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEP---LKSMIVRQGES 751 +TN+ +E + V A NR G + S + + E P++ L + ++ G Sbjct: 495 VTNLIPGREYLFRVFAENRAGLSTPSPESDHHVAKAQFEAPKIDTSGFGLGDLRIKAGAR 554 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 ++ VG P P + W K+NK +K T +++S + + D+G Y +K +N Sbjct: 555 FDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTTESNSTLLCSFAERGDQGSYMIKLDN 614 Query: 810 SEGIAETSA-VITVEEPTEENAEPPLFINRFQEITVK 845 S G S V+ ++ PT P+ + F + +V+ Sbjct: 615 SRGSDSYSLNVLVLDRPTAPGG--PIEYSEFTKESVR 649 Score = 41.9 bits (94), Expect = 0.19 Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 5/124 (4%) Query: 704 QEGTYTVVAVNRE--GEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVG 760 +E + V A N E G+ S P + + E P++ I L+ + V+ GE ++ + G Sbjct: 903 EELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTG 962 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818 P PT TW + PVK + T LK +D G YT+ +N G Sbjct: 963 FPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQDAGRYTITVKNDSGSDTARV 1022 Query: 819 VITV 822 +TV Sbjct: 1023 KVTV 1026 Score = 38.7 bits (86), Expect = 1.7 Identities = 27/128 (21%), Positives = 53/128 (41%), Gaps = 1/128 (0%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +E + ++A N E + SA ++ P L I ++I VK ++ +T Sbjct: 903 EELEFRVRANNDECPGKPSAPTPATVIEDKPERPKLDIGSLEDIKVKGGEKFEINLPLTG 962 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P+ TW + + S + +L + + + + D+G Y N +G + Sbjct: 963 FPTPTATWELGSSPVKESGRVLVTTARTYTKLKVDSAERQ-DAGRYTITVKNDSGSDTAR 1021 Query: 919 ARVTIDVE 926 +VT+ E Sbjct: 1022 VKVTVIAE 1029 Score = 37.9 bits (84), Expect = 3.0 Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 1/127 (0%) Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 V E + + A N G + S ++ + A P L ++ ++I +K L Sbjct: 204 VNKELEFRVAAVNKAGTGKPSECSAPQKTKPKFARPTLKGDKLRDIKIKAGQEFVLSVIF 263 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P I+W N ++ S+ + + E E+ + D D+G Y+ +N +G Sbjct: 264 EAAPAPEISWTLNGNKVTGSDHVGLKNEEELTEVKVKMADKS-DTGTYELKLTNDSGDVK 322 Query: 917 HGARVTI 923 V + Sbjct: 323 TSCNVIV 329 Score = 37.5 bits (83), Expect = 4.0 Identities = 35/159 (22%), Positives = 64/159 (40%), Gaps = 14/159 (8%) Query: 768 WCK-NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W K +PVK L +++T L P + E ++ + AEN G++ S Sbjct: 480 WVKATREPVKTL-------AYTVTNLIPGR---EYLFRVFAENRAGLSTPSPESDHHVAK 529 Query: 827 EENAEPPLFINRFQ--EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 + P + + F ++ +K + P P + W ++N+ + PS+ T + Sbjct: 530 AQFEAPKIDTSGFGLGDLRIKAGARFDINVPFVGAPAPGVEWVKDNKEMKPSDRFTVDTT 589 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 N L+ + + D G Y NS G S+ V + Sbjct: 590 ESNSTLLCSFAERG-DQGSYMIKLDNSRGSDSYSLNVLV 627 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 7/90 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQT---AIIKPSQDFQMYYDDDNVATLVIR-EVFPEDAG 579 G + E EG P P ITW R ++PS ++ ++D +++++ E DAG Sbjct: 1245 GEKFRVEISFEGSPPPNITWSRSDKNGITVEPSN--RIAFEDTELSSIMANSEAERGDAG 1302 Query: 580 TFTCVAKNAAGFASSTTELI-VEAPLSDHG 608 T+ N G ++T +I V+ P + G Sbjct: 1303 TYAVTFSNEKGTDTATVRIIVVDKPSAPEG 1332 >UniRef50_Q4T444 Cluster: Chromosome undetermined SCAF9829, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome undetermined SCAF9829, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 9369 Score = 254 bits (623), Expect = 1e-65 Identities = 151/476 (31%), Positives = 220/476 (46%), Gaps = 8/476 (1%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G + + A ++G P P V W K L D I T+ S + I R ++ Y Sbjct: 3168 RAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYI 3227 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 IEA N G ++ + + + DKP P I EI+ ES + W PP DDGG +T Y +E Sbjct: 3228 IEAVNVCGRATATIDVNILDKPGPPAAFDIS-EITSESCCLAWNPPRDDGGSPITNYIVE 3286 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + D WIK++ + T+ KL EY+FR+ A+N G E E PIV K + Sbjct: 3287 SRQTDKEEWIKLSATVKHT-TFKACKLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSF 3345 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW--KXXXXXXX 1821 D P I ++V +TWF +++GGSPI Y VE E +KW Sbjct: 3346 D-PPGSPTRVTPSDITKDAVTLTWFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKD 3404 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 R++ L Y+FR+ A N G + D + I + PP P V + S Sbjct: 3405 TSFRVKGLRTKKKYRFRVLAENLAGPGKASSETDPVLIKDPIDPPWAPGKPAVRDVGKTS 3464 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 L WT PE +GG+ I YIIEF+ + W + + EH ++ +KEK E FR+ Sbjct: 3465 ALLAWTRPEHDGGAKIEGYIIEFQKTGSEEWV-CIAENVPLTEHQLQGLKEKQEYSFRVK 3523 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 A N G S P+E + K P P LE+ + W P DGG+P+ Y Sbjct: 3524 AVNKAGESEPSEPSDPVICKERLYPPSPPQWLEVSNITRINAELKWQVPSSDGGSPITNY 3583 Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + RDV + W V V LK+ + L+E Y+ R+ A N +G+SE E ++ Sbjct: 3584 VVEKRDVRRKTWQSV-DTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCELED 3638 Score = 235 bits (575), Expect = 1e-59 Identities = 186/735 (25%), Positives = 314/735 (42%), Gaps = 30/735 (4%) Query: 1346 TIKKVENTDAGIYKLRLENNCG-----HADVEMNVTI-LDKPSPPGKPNILEIDSSSINI 1399 T+ V ++ + N CG + D +N++ P PP + + SI + Sbjct: 3012 TVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLKWRDKCAKSIFL 3071 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W+ P+ G S + YVV+ + T +W + + + + + L Y +R A N+ Sbjct: 3072 LWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQVSGLLEGQWYSYRVRAFNK 3131 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 + S S T+ + + + ++ K L +T IEL G P P+V W + Sbjct: 3132 LGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADVKGKPAPRVKWTK 3191 Query: 1518 DGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 L+ T + Y A N G + V I KP Sbjct: 3192 ADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATATIDVNILDKPGP 3251 Query: 1574 TISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 + DI + W G P I + + ++ ++ K + + Sbjct: 3252 PAAF-DISEITSESCCLAWNPPRDDGGSPITNYI--VESRQTDKEEWIKLSATVKHTTFK 3308 Query: 1632 IKELKRSHSSKYTIEASNTAGTSS----VEVTLKV-YDKPSKPEGPVIMREISRESVTIE 1686 +L + I A N G V + K +D P P V +I++++VT+ Sbjct: 3309 ACKLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSFDPPGSPTR-VTPSDITKDAVTLT 3367 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W P +DGG +T Y +EK +P++ +WI+ + ++ ++ L +Y FRV+A+N Sbjct: 3368 WFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKDTSFRVKGLRTKKKYRFRVLAENL 3427 Query: 1747 VGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G +A E++P++IK +D P + S + W E +GG+ I Y +E Sbjct: 3428 AGPGKASSETDPVLIKDPID-PPWAPGKPAVRDVGKTSALLAWTRPEHDGGAKIEGYIIE 3486 Query: 1806 IKQEG-KKWK-XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 ++ G ++W ++Q L Y FR+ A N+ G S P D + + L Sbjct: 3487 FQKTGSEEWVCIAENVPLTEHQLQGLKEKQEYSFRVKAVNKAGESEPSEPSDPVICKERL 3546 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 PPS P+ VS T + LKW P S+GGSPITNY++E + V+ K+W + T + Sbjct: 3547 YPPSPPQWLEVSNITRINAELKWQVPSSDGGSPITNYVVEKRDVRRKTWQSVDTTVKDL- 3605 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNI 1982 ++ + + E +FR++AEN+VG+S E + L K T P PP A L + V Sbjct: 3606 KYIVSPLNEGSLYVFRVAAENSVGMSEFCELEDAVLAKDTFTTPGPPYA-LTVLEVTKRH 3664 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 V W P+ DGG P+ Y I ++ T W++ K +F + D+ E ++ Sbjct: 3665 VELKWEAPKSDGGRPITKYVIEKKEKLGTRWLKCCKTPDKQSQFKVTDVDEGSEVQFQVR 3724 Query: 2043 ARNEIGLSEPLESDE 2057 A NE G+ +P E E Sbjct: 3725 AENEAGVGDPSEPTE 3739 Score = 235 bits (574), Expect = 1e-59 Identities = 185/748 (24%), Positives = 331/748 (44%), Gaps = 37/748 (4%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHS 788 +E P+ + L ++ + +SV + +V +TW + + + + DG Sbjct: 1925 EEAPKFTKNLSNVEGMETDSVKMICEV-SKASAEVTWYRGEEELPEVGRYEQIMDGRKR- 1982 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 I I+K +++D G YT + + +TSAV+ + E E FI+R Q V E Sbjct: 1983 ILIIKGLRMEDAGQYTCRLSPN---IKTSAVLQLNELAAE------FISRPQNQEVVEGQ 2033 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 + V++ + W+R ++ + + +G+ L + N + + D G Y VA Sbjct: 2034 AAEFTCSVSKETY-EVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCELK-DEGGY--VA 2089 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEI 967 A K+S VT + +T +K E +EG ++ C+ + KW N++ I Sbjct: 2090 HIGAIKASADLLVTEKLRVITPIKDT----EVKEGSEIVFNCEANAEGAKAKWLKNEETI 2145 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLV---VKETIPEFIRK 1022 + Q D + +Q E +T V E F++ Sbjct: 2146 FETSKYMMAQRDNVFSLRIRDAQKTDEASYTVSLTNQRGEQATCTASAKVAEEKHRFLQP 2205 Query: 1023 LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 ++D E +EK ++N V W + G+ + K + + G L I++ + Sbjct: 2206 IEDIETQEKKTISFVCKVNRPEVMVKWTKAGQEVALSK-RIVYRADGLKHTLTIKDCVME 2264 Query: 1083 DEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD 1142 DEGEY+ ++ ++ CTA++ V E P + L++Q V + A F +L K A V+W+K+ Sbjct: 2265 DEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADFTCKLNKEKASVKWYKN 2324 Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL 1202 G EI+ + +GK +L I +C DD EY+C + + A L VEE + +R Sbjct: 2325 GREIREGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTRARLFVEETPVEI-IRP 2383 Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 P+ +L P +D VE+ + ++V W + +I +K+ +IS+ K L + + D Sbjct: 2384 PQDMLEPPASDIVFEVELNKDRVEVKWMRNNMIIVQGDKYQMISEGKIHRLQVCEIRPRD 2443 Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 Q EY V D + KL++ V PKI +++ G + V Y A+P+ EW Sbjct: 2444 QGEYRIVAKDKDARAKLELAAV---PKIKTTDQKLVTDAGKPFIMRVPYDAYPRAEAEWF 2500 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + ++ S+D +K D G YK+ + N G A+ + + ++D P Sbjct: 2501 FEDTSL-PVQNIDTSVD--KTEYRLKSPSKEDQGQYKVVISNKHGAAEAFIVLDVIDVPG 2557 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQ 1441 +L+ +++ W+EPE+ G S II YVVE +++ W ++ + + Sbjct: 2558 SVKNLRVLDTADGEVSLAWEEPESDGGSKIIAYVVERRDVKRKTWALATDRADTPEYCVT 2617 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTE 1469 L +S+Y FR A N V A T + Sbjct: 2618 GLHKDSAYLFRVCARNRVGSGPAVVTED 2645 Score = 230 bits (563), Expect = 3e-58 Identities = 229/868 (26%), Positives = 376/868 (43%), Gaps = 62/868 (7%) Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 +W DG +I + G L I +C D GEY V N + + + ++ Sbjct: 6544 KWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYVLIVTNPAGSKTVALHVTVLD 6603 Query: 1198 FTLRLPEFILVPANTDAYLTVE--IP--DETLDVTWY--KKKSVIEDTEKFTLISDVKKR 1251 I + T Y+ ++ P D +T Y +KK V + E ++++S Sbjct: 6604 LPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVKKPWEPWSVVSSSGTN 6663 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG----SDVT 1306 T E + EY ++ ++ K+ + +E PP I + G SD+T Sbjct: 6664 TKAKVSRLEKGR-EY---VVRVRAENKIGISTGLESPPTIAKHMFNPPGPPGLPVCSDIT 6719 Query: 1307 ---LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIK-KVENTDAG-IYKL 1360 + V++ P + ++ +I++ + T I +K+ L ++ +V G Y+ Sbjct: 6720 ENAVTVEW-TLPDYDGGSPISGYVIERREMTGKWIRVNKTPVLDLRYRVSGLFEGNSYEF 6778 Query: 1361 RL--ENNCGHADVEMN------VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 R+ EN G +D + + +P PPG P + + S +ICW +P G S + Sbjct: 6779 RVFAENIAGISDPSLASDPVKAARAITRPGPPGNPKLRDWSKSYADICWTKPTRDGGSPV 6838 Query: 1413 IYYVVEYQEIDTTEWISV-KNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + YVVE Q+ + +W + K++ K + L YRFR A N+V S+ E E Sbjct: 6839 LGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRIRAANKVGESEPRELAE- 6897 Query: 1471 YKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 V+ + + P TV+ ++ T + I L I+ P+ W R K K T Sbjct: 6898 -TVLAKDILVPPEVTVDVSCRDALTIRADQI-LNLIYEKKPKSSEEWERLHKG--AIKET 6953 Query: 1529 YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH---- 1584 Y ++ N+ GE + K I IK Sbjct: 6954 Y-----FMADRCIENQIYQFRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVV 7008 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT--SVIRIKELKRSHSSK 1642 K GD + A+++G P P+V W K+ + E K + + T S + + +R+ S K Sbjct: 7009 KAGDSIPIEAMVKGKPQPDVKWTKDNSTEEIKKGPRVQIENGTDFSKLLLTGARRTDSGK 7068 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y I +N+AG+ S T+ V D+P P + + IS + + W+ P D+GG ++ Y Sbjct: 7069 YVIAVTNSAGSCSAFATVSVLDRPG-PVQDLKVSGISIDRCHLAWEAPEDNGGCDIYNYI 7127 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 IEK E W ++ +T + +L E EY+FRV A+N +G A++SEPIV T Sbjct: 7128 IEKCETKRGVWSVHSNAVITNKTK-VTRLIEGNEYIFRVRAENKMGPGPAVQSEPIVAGT 7186 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXX 1821 VP I E + + W EK+GG PI Y +E ++E +W Sbjct: 7187 QFSVP-YAPEMPEVTKIAKEEMTVQWSEPEKDGGKPITGYLLEKREEHAVRWSPVNKDPT 7245 Query: 1822 XXARIQKLSINTT--YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 + YQ+R+ A NEIG S P S +T + PP+ P N V +ST Sbjct: 7246 PATHFTVTGLIPLHDYQYRVKAVNEIGISSPSKSSRAVTAKDAVGPPAPPSNLRVLDSTK 7305 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFK----TVKGKSWTKIVTVGGS--VHEHCIENIKEK 1933 +VTL WT+P S GG+PI Y++E + KG K V V + + ++ ++ Sbjct: 7306 STVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQLVVCDFTVTSLDDQ 7365 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEK 1961 FR+SA+N VG+SLP + + + K Sbjct: 7366 LVYEFRVSAQNQVGMSLPCDLKDAVIPK 7393 Score = 229 bits (561), Expect = 5e-58 Identities = 170/691 (24%), Positives = 291/691 (42%), Gaps = 27/691 (3%) Query: 1282 EVVEFPPKIVDYERE--YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 +++ P ++ E + + G+ + L + P+P W + IK + Sbjct: 8232 DIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITWAKMNTNIKDRQGIVIKSS 8291 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 + + ++ V DAG Y LE+ G + V + D P PP + E +I Sbjct: 8292 NTDTIVMVENVNRYDAGKYIFNLESLAGMKMYTIVVKVYDTPGPPVNLMVKETSKDGASI 8351 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNE 1458 WD P G + +Y+VE ++ + W V N KT + +L SY FR V+ Sbjct: 8352 FWDSPLTDGGYEVTHYIVEKRDTERKAWSIVSMNCNKTSFEVPDLNAGRSYCFR---VSG 8408 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDIELTCIFGGVPQPKVTWYR 1517 V+ A E E ++ + + P K + T+ + I +++ Sbjct: 8409 VNKLGAGEYCETADSVRAS--EEPGAVMDFKTVLVTKDSCTISWKKPLSDGGSRIISYVL 8466 Query: 1518 D--GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 + K + Y+ A ND GE + + + +I Sbjct: 8467 EVLNGDDKYKELMRSKNMQYSAKDLVEGKEYTYRVKAINDSGEGAAKELTVVAKDQIIH- 8525 Query: 1576 SNEDIKQKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTS 1628 N D+++ K G + I G P P+V W K ++ L++ + + Sbjct: 8526 PNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDDEDLKDSGRVCAESSSVNT 8585 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 + I++ +R+ +SKYTI N+AG + ++V KP P GP+ ++++ + T++W Sbjct: 8586 TLLIRDCQRNDASKYTITLRNSAGIKESTIFIRVVGKPGIPVGPIKFKDVTADGATLKWG 8645 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 P DDGG ++ Y +EK + N W+ V+ + + + L+E EY+FRV A+N G Sbjct: 8646 APKDDGGSDIANYILEKRDSVTNMWVTVSS-SVETNSMRVTGLHEGTEYIFRVCAENKYG 8704 Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 E L+S+PI+ K +VP + + S Y+ W K GGSPI Y +E K+ Sbjct: 8705 VGEGLKSDPIIAKHPFNVPE-APPPPQIMNMQHNSAYLAWLDPRKTGGSPITGYHLEFKE 8763 Query: 1809 EGKK-WKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 WK + L+ Y+FR+ A N G P D + Sbjct: 8764 RNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRVMAINLAGIGKPSAPTDPRVALDPIDV 8823 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P +P +++ST VTL+W EP+ +GG +T YIIE + + K W K V Sbjct: 8824 PGKPEVISITKST---VTLQWIEPQFDGGHRLTGYIIEKRDLPSKIWMKANNVNVLEPAF 8880 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + +++E + FRI A+N G P Q+ Sbjct: 8881 TVMDLQEGCKYEFRIRAKNAAGAISPASEQT 8911 Score = 229 bits (560), Expect = 6e-58 Identities = 204/857 (23%), Positives = 363/857 (42%), Gaps = 67/857 (7%) Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIV-DYEREYRIKRGS 1303 +++ + ++I D + + A ST ++ + P PK+ ++ ++ + Sbjct: 5196 AEILTQDILIEPTVTLDVSAHDLLNCRADSTIRIPATITGRPLPKVTWTFDGTAETEKKN 5255 Query: 1304 DVTLL-VDYQAFPQPNDEWIVNS--KIIKKCKHTKPSIDSKSAS--LTIKKVENTDAGIY 1358 D+ +L VD + P E I ++ K + H I S + +TI + +G Y Sbjct: 5256 DLHILPVDSEVRPFSLGELIYHNAFKSLTLFPHVSFQIHSSDTTSVVTIPISKLAHSGRY 5315 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + E+ GH V++ VT+LD P PP + ++ + + W P+ G + Y +E Sbjct: 5316 IINAESPAGHKVVKVRVTVLDLPGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIE 5375 Query: 1419 YQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE- 1476 + + W V Q+ + +L Y FR A N ++T E K Sbjct: 5376 KKTVHGKAWTKVNPACAAQSLVVPDLNNGQEYLFRIRAENRFGFGPFTQTIERTKASDPI 5435 Query: 1477 ------TKIQSPTVEKPLKNITTE-PNED---------IELTCIFGGVPQPKVTWYRDGK 1520 T+++ V K +T + P D ++L C Q K W R + Sbjct: 5436 NPPDPPTRLKIQNVHKGAVTLTWKAPKNDGGSPVTHYSVDLLCWDASGTQ-KEHWRRCNR 5494 Query: 1521 K-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG---IQ-QKPVITI 1575 + +++ + E+ ++ +A+N+ G S G IQ Q +I Sbjct: 5495 RDVESTRFKVED--------LTYGDEYEFRVVAYNEAGPSRPSTTAGPITIQDQSCAPSI 5546 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-----NGNKLE--NDKEYNITTKEKTS 1628 ++ + + G + + A I G P P + WYK + NK+E D+ N + + Sbjct: 5547 ELQEFMEVEQ-GSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSC 5605 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 + I++ KR + YT+ ASN+ G +S E+ L V +P P P+ EI E +T+ W Sbjct: 5606 TLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNVLGRPGPPSAPIKFEEIGAERITLSWL 5665 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 PP DDGG ++T Y I + + W+ V ++ + ++ L EY+FRV+AQN G Sbjct: 5666 PPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKE-RIWTVENLMTGHEYVFRVMAQNKYG 5724 Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 E L+SEP V + P +D ++ G II Y Sbjct: 5725 VGEPLDSEPEVARDLYIGPE----------VDLDTSVKEKMVVHAGGVIRIIAYVSGQPT 5774 Query: 1809 EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYTSDDK--ITIGKT 1862 W A+++ I++ + +R +G T+ + K +T+ Sbjct: 5775 PDITWSRDGSALPPEAKVETTFISSALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVL 5834 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P F ++ S L W PE++GGSPI+NYI+E + + K+WT V+ S Sbjct: 5835 DVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIVEKREAERKAWTS-VSFTASR 5893 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSN 1981 + FR++AEN +G+ E+ + V + + ++P P LE+ V + Sbjct: 5894 TNAVAHGLTSGKSYFFRVAAENAIGIGPFVETAAEVVIREPISIPERP-EELEVHKVTKD 5952 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 ++ +W P+ DGG+ + Y + R + K + + K + K+ L E TY R+ Sbjct: 5953 LISVTWKPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRV 6012 Query: 2042 YARNEIGLSEPLESDEP 2058 A NE+G +P +P Sbjct: 6013 IAVNEVGPGKPSFCTKP 6029 Score = 206 bits (503), Expect = 5e-51 Identities = 214/942 (22%), Positives = 380/942 (40%), Gaps = 64/942 (6%) Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + W K+ K P K + +DG +T+ K +K + G YT G +T+A + + Sbjct: 1513 VKWFKDGKELTPSKNIAIITDGKKRILTVRKAEKA-NIGEYTCDC----GSDKTTAKLNI 1567 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 EE + P + V E T K ++ + V W E + S + Sbjct: 1568 EERDIKIVRP------LYSVEVTETETAKFETEISEDDVHG-NWKLKGEALQQSADVEMK 1620 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 +G LV+ NV ++ +G A+N+ +SS A++ + V V+ L K Sbjct: 1621 EEGTRHMLVLYNVHMDM-AGAVDFSAANA--RSS--AQLRVKARSVGLVRPL-KDVMVTA 1674 Query: 943 GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 G+T EC+ S+ + +W+ +++ + + GR + G +K Sbjct: 1675 GETATFECELSYEGIVVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTA 1734 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 KD +T L+VKE EF + L+D V+E LE ++ E A+V W RDG+ ++ K Sbjct: 1735 KDFQTQAHLIVKEPPVEFTKPLEDQTVEEDSTVTLECAVSRENAEVRWFRDGQELR-KTK 1793 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 K+D G R L I N S D Y+C +D + + V E LQ+ +V + Sbjct: 1794 KFDLLSLGCKRMLVIHNCSSEDIKMYTCDTKDFKTSCYLDVTPPHVEFTKLLQDVEVRER 1853 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 A FE E+++ A VRWFKDGSEI+ ++T G ++ L I+ DD EY C+ Sbjct: 1854 EAAKFECEVSRESAKVRWFKDGSEIRKGKKYEITASGVQRTLIIHKSGFDDEAEYECDAR 1913 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAY-LTVEIPDETLDVTWYKKKSVIEDTE 1240 SK + +LTV E + FT L + TD+ + E+ + +VTWY+ + + + Sbjct: 1914 TSKTSGLLTVIEEAPKFTKNLSN--VEGMETDSVKMICEVSKASAEVTWYRGEEELPEVG 1971 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300 ++ I D +KR LII+ +D +YTC L T +++ E + + + + Sbjct: 1972 RYEQIMDGRKRILIIKGLRMEDAGQYTC-RLSPNIKTSAVLQLNELAAEFISRPQNQEVV 2030 Query: 1301 RG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 G ++ T V + + +W K ++ + K LT+K E D G Y Sbjct: 2031 EGQAAEFTCSVSKETY---EVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCELKDEGGY 2087 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + A ++ VT + P K E+ S I ++ N + + E Sbjct: 2088 VAHI--GAIKASADLLVTEKLRVITPIKDT--EVKEGS-EIVFNCEANAEGAKAKWLKNE 2142 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 +T++++ + I++ + + N+ + + T KV +E Sbjct: 2143 ETIFETSKYMMAQRDNVFSLRIRDAQKTDEASYTVSLTNQ--RGEQATCTASAKVAEE-- 2198 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX 1538 +P+++I T+ + I C P+ V W + G+++ +K Sbjct: 2199 --KHRFLQPIEDIETQEKKTISFVCKVNR-PEVMVKWTKAGQEVALSK-------RIVYR 2248 Query: 1539 XXXXXXXXXYKCIAFNDHGEV-----ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 K D GE E C + +K + E Sbjct: 2249 ADGLKHTLTIKDCVMEDEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADF 2308 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT--IEASNTA 1651 V WYKNG ++ Y++ + K + IKE + +Y ++ T Sbjct: 2309 TCKLNKEKASVKWYKNGREIREGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTR 2368 Query: 1652 G-----TSSVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEW 1687 + VE+ D P ++ E++++ V ++W Sbjct: 2369 ARLFVEETPVEIIRPPQDMLEPPASDIVFEVELNKDRVEVKW 2410 Score = 205 bits (501), Expect = 9e-51 Identities = 137/451 (30%), Positives = 209/451 (46%), Gaps = 17/451 (3%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVE-----VTLK-VYDKPSKPEGPVIMREIS 1679 K + R+K L+ ++ + A N AG V +K D P P P + R++ Sbjct: 3403 KDTSFRVKGLRTKKKYRFRVLAENLAGPGKASSETDPVLIKDPIDPPWAPGKPAV-RDVG 3461 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 + S + W P DGG ++ Y IE + + W+ +A+ + + + +Q L E EY F Sbjct: 3462 KTSALLAWTRPEHDGGAKIEGYIIEFQKTGSEEWVCIAE-NVPLTEHQLQGLKEKQEYSF 3520 Query: 1740 RVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 RV A N G SE E S+P++ K L PS I + + W +GGSP Sbjct: 3521 RVKAVNKAGESEPSEPSDPVICKERLYPPSPPQWLEVSN-ITRINAELKWQVPSSDGGSP 3579 Query: 1799 IIDYKVEIKQEGKK-WKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 I +Y VE + +K W+ I L+ + Y FR+ A N +G S +D Sbjct: 3580 ITNYVVEKRDVRRKTWQSVDTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCELEDA 3639 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 + T T P P V E T R V LKW P+S+GG PIT Y+IE K G W K Sbjct: 3640 VLAKDTFTTPGPPYALTVLEVTKRHVELKWEAPKSDGGRPITKYVIEKKEKLGTRWLKCC 3699 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEI 1975 + + ++ E E+ F++ AEN GV P+E ++ + +E + PSPP L I Sbjct: 3700 KTPDKQSQFKVTDVDEGSEVQFQVRAENEAGVGDPSEPTEILNIEDPTSAPSPP-LDLTI 3758 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM-WMEVGKVDVNTLKFNIRD-LSE 2033 + +W P DGG P+ GY++ + + + W+ V + LKF I D + Sbjct: 3759 PDASREHITATWKPPAKDGGCPISGYHVEVAEARPELKWLRVNNRPIKELKFRIDDGIKP 3818 Query: 2034 NHTYMIRIYARNEIGLSEPLE-SDEPFKVIP 2063 Y+IR+ A N +G +P E +D+ F P Sbjct: 3819 EKKYVIRVRAINSVGTGDPSEITDKIFTKDP 3849 Score = 195 bits (475), Expect = 1e-47 Identities = 190/802 (23%), Positives = 321/802 (40%), Gaps = 48/802 (5%) Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-------NSKIIKKCKHTKPSIDSKSA 1343 ++ + +++GSD++++ + P P W N ++ +H + S Sbjct: 5546 IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSC 5605 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWD 1402 +L I++ + D G+Y L N+ G A EM + +L +P PP P EI + I + W Sbjct: 5606 TLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNVLGRPGPPSAPIKFEEIGAERITLSWL 5665 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDI 1461 P++ G S + YV+ + + W+ V + K + +++NL T Y FR A N+ + Sbjct: 5666 PPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKERIWTVENLMTGHEYVFRVMAQNKYGV 5725 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPL---KNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + ++ +V ++ I P V+ + + I + G P P +TW RD Sbjct: 5726 GEPLDSEP--EVARDLYI-GPEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRD 5782 Query: 1519 GKKLKTAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV--- 1572 G L +A E Y A N GE + + V + P Sbjct: 5783 GSALPP-EAKVETTFISSALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVLDVPGPVG 5841 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I + E++ W G P I K + + + T +V Sbjct: 5842 IPFTTENLSND-SCKLNWFFPENDGGSPISNYIVEKREAERKAWTSVSFTASRTNAVAH- 5899 Query: 1633 KELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKP--SKPEGP--VIMREISRESVTIEW 1687 L S + + A N G VE +V + S PE P + + +++++ +++ W Sbjct: 5900 -GLTSGKSYFFRVAAENAIGIGPFVETAAEVVIREPISIPERPEELEVHKVTKDLISVTW 5958 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 KPP DGG E+T Y +E +++ ++ Y L E Y FRVIA N V Sbjct: 5959 KPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRVIAVNEV 6018 Query: 1748 GFSE-ALESEPIVIKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIIDYK-- 1803 G + + ++PI K L+ P+ I ES + + K S I Y+ Sbjct: 6019 GPGKPSFCTKPITCKDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPS-IAWYRDD 6077 Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 E+K + K + K + ++ + N G+ + +T+ Sbjct: 6078 EEVKAD-KHVMFKNTLTTMSLGLMKAQREHSGRYVVVVENSTGSRKGICN---VTVVGVP 6133 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG-GSV 1922 P P V E + + + W P +GG PITNYI+E K K W++ Sbjct: 6134 EAPEMP---TVREVYATNALVLWNRPR-DGGKPITNYILEKKETMAKRWSRATREPLYPA 6189 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-PSPPTAPLEIRMVGSN 1981 + ++++ E E FR+ AEN +G P+E L K V PSPP P E + Sbjct: 6190 TQFRVQDLVEGCEYEFRVMAENELGTGDPSEPSKPILAKDPIVCPSPPVTP-EAYDKTKD 6248 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK--VDVNTLKFNIRDLSENHTYMI 2039 V W P DG + GY + + W++ + L F + L++ Y+ Sbjct: 6249 SVSLKWKLPRHDGKGRIFGYLVEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVF 6308 Query: 2040 RIYARNEIGLSEPLESDEPFKV 2061 RI+ N G S+P EP KV Sbjct: 6309 RIFTVNAAGKSDPAYIREPIKV 6330 Score = 194 bits (472), Expect = 3e-47 Identities = 185/711 (26%), Positives = 291/711 (40%), Gaps = 50/711 (7%) Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 VVEF + ++ I+ G + L PQP +W + I K + + + K+ Sbjct: 4502 VVEFDASV---KKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMIVET-EGKN 4557 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 +SL IKK TD G YK+ N+ G E V I+D P P + + +I + W Sbjct: 4558 SSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVPGPVVDLKTVTVTKKNITLTWS 4617 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 +P + G S II Y V ++ + + IQ L Y FR A N+ Sbjct: 4618 DPHDNGGSDIIGYDVLRKDAKMKLFRHPMETASCKCDIQGLLAGEEYDFRVIARNKYGDG 4677 Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC----IFGGVPQPK--VTWY 1516 S+ ++ + +P+ + L + T I L GG P V Sbjct: 4678 APSDLGP---ILAQDPKGTPSAPEKL-HYTDRGKTTIMLAWQPPRTDGGSPIRGYYVEKM 4733 Query: 1517 R-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQK--- 1570 R D + + A ++ A N+ G+ E S + IQ Sbjct: 4734 RSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELA 4793 Query: 1571 PVITI-----SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK- 1624 PVITI SN I +K D + A ++G+P P + W K+ +E E + + Sbjct: 4794 PVITILKFFKSNAIIIKKGSAID---IPAEVKGLPLPSLQWVKDDVVIETPVEDKMIMET 4850 Query: 1625 ---EKTSV---IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 ++T++ I I E R Y + A N G + + +++ D+P P V++ +I Sbjct: 4851 EEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFGKAQHVIRVEILDRPLPPRN-VVVSDI 4909 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEY 1737 +S + W P D+GG E+T Y IE+ + + +V + Y + KLN N Y Sbjct: 4910 KADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQTTNLIDRRYGVYKLNVNGAY 4969 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FR+ A+N G S+ +SE + + +P ++ +TW P NGGS Sbjct: 4970 QFRIKAENKYGISDGCDSEKVQLSDPFGLPGPPRNPKIIAATAT-TMTLTWDPPLDNGGS 5028 Query: 1798 PIIDYKVEIKQEGKK-WKXXXXXXXXXARIQ-------KLSINTTYQFRIYARNEIGTSL 1849 I Y +E ++ G W ++ KL T YQFRI A N G Sbjct: 5029 TIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAGVGP 5088 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 P + + PPS P V + T S+TL W+ P+ +GGSP+ YIIE Sbjct: 5089 PSEASECRFAVDPCNPPSSPGAPEVKDKTKNSITLSWSPPDKDGGSPVKGYIIEVHEEGC 5148 Query: 1910 KSWTKIVTVGGSVH---EHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 W + V +H E + ++KE + FRI A N G S P + + Sbjct: 5149 PDWRR-VNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAEI 5198 Score = 188 bits (459), Expect = 1e-45 Identities = 110/396 (27%), Positives = 186/396 (46%), Gaps = 6/396 (1%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G ++ A + GIP P W +G + ++ +I T ++++ I E +R + +Y Sbjct: 6524 KAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYV 6583 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + +N AG+ +V + + V D P P GP+ + E++ + + I+W+ P DDGG +T Y +E Sbjct: 6584 LIVTNPAGSKTVALHVTVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVE 6643 Query: 1705 KHEPDN--NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 K + W V+ + + + +L + EY+ RV A+N +G S LES P + K Sbjct: 6644 KKDVKKPWEPWSVVSSSGTNTKAK-VSRLEKGREYVVRVRAENKIGISTGLESPPTIAKH 6702 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW--KXXXXXX 1820 + P +N +V + W + +GGSPI Y +E ++ KW Sbjct: 6703 MFNPPGPPGLPVCSDITEN-AVTVEWTLPDYDGGSPISGYVIERREMTGKWIRVNKTPVL 6761 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 R+ L +Y+FR++A N G S P + D + + +T P P N + + + Sbjct: 6762 DLRYRVSGLFEGNSYEFRVFAENIAGISDPSLASDPVKAARAITRPGPPGNPKLRDWSKS 6821 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 + WT+P +GGSP+ Y++E + W +I + + + + E E FRI Sbjct: 6822 YADICWTKPTRDGGSPVLGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRI 6881 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 A N VG S P E L K VP T + R Sbjct: 6882 RAANKVGESEPRELAETVLAKDILVPPEVTVDVSCR 6917 Score = 179 bits (436), Expect = 7e-43 Identities = 131/434 (30%), Positives = 197/434 (45%), Gaps = 18/434 (4%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKV----YDKPSKPEGPVIMR--EISRESVT 1684 R+K + + + +Y +E N T V++ + + +D KP+ P+ + + + +S+T Sbjct: 4059 RVKAVNKVGAGQY-LELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKSIT 4117 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 I WK P +DGG + Y +EK E D +R+ +V ++ + L EN EY FRV A+ Sbjct: 4118 ITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVRAE 4177 Query: 1745 NPVGFSEALESEPIVIKTA--LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 N G SE S + +K A +D P I N SV W P E +GGS I++Y Sbjct: 4178 NVAGVSEPSRSTQL-LKAADPVDKPGAPINFTFDE-IRNTSVICNWEPPEDDGGSEILNY 4235 Query: 1803 ---KVEIKQEGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 K + K+E W + + KL Y FR+ A N+ G P S +T Sbjct: 4236 ILEKRDYKKEEVGWITITSTLKGNSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGP-LT 4294 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 PP P V E T+ + L W EP+ NG SPI Y IE K V K WT++ Sbjct: 4295 AKNQFDPPDAPNTPRVHEVTASTARLSWHEPKDNG-SPILGYWIERKEVNSKHWTRVNRA 4353 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 + E + N+ E IFR+ AEN G +E A +P P P + Sbjct: 4354 LINSLEVKVSNLMEGLTYIFRVCAENLAGPGPFSEPSDRTTAMDAILPPGPPTPWIVD-T 4412 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 G + V+ +W P ++GG +LGY++ + W + L F + L E Y Sbjct: 4413 GKDFVIVAWKPPLYNGGGDILGYHVEKVLAGEKEWTRSTEFRCKDLTFTVTGLIEGADYY 4472 Query: 2039 IRIYARNEIGLSEP 2052 IR+ A N+ G P Sbjct: 4473 IRVVAINDAGPGAP 4486 Score = 179 bits (435), Expect = 9e-43 Identities = 180/704 (25%), Positives = 296/704 (42%), Gaps = 40/704 (5%) Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VA N G + T I A D G+ +LE I K + Q Sbjct: 677 VAINIIGLQHAVT--IQNATEEDTGAYTCEVEGREDISTTTNVKVLEIIKDWLVKPLRDQ 734 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAIESDMHMYCSVLKITNVKK 702 +V S + L P+ WL KGE EI P E + +A + L I N + Sbjct: 735 HVKPKSKATFKGELFK-DTPNWKWL-KGETEITPSEKMEIAKDGAN----VTLTINNCQP 788 Query: 703 FQEGTYTVVAVNREGEASLPI--VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 YT+ +R A L + ++ + E+E ++++PL S+ V + E ++ Sbjct: 789 DDVSEYTIEVEDRRYTAKLTLGGAVRRRFQEREA-EILKPLASLEVVEKEEANFDTEI-- 845 Query: 761 NPRPTI-TWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 + I W + + PT K +G +T LK +V G + +A N A T Sbjct: 846 SEEDIIGEWKLRGQVLTRSPTCDIKLEGRKRFLT-LKNVQVDQAGEVSYQALN----AVT 900 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 + ++TV+E E F++ ++++V EK K VT+ VP + W++ EI++P Sbjct: 901 TGMLTVKE-LEMG-----FVDPLKDVSVPEKKQAKFECTVTKE-VPKVMWFKGAEIVTPG 953 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 DG LVI + + + D Y S ++ ++ ++ FV+ LQ Sbjct: 954 PKYEIIDDGLKHMLVINSCEFD-DEAQYTIEVLGQRSSS----QLRVEGIRLNFVQPLQD 1008 Query: 937 SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 +EGKT E + +H V WY N+ ++ + EG+ D Sbjct: 1009 Q-TVKEGKTAHFELELTHDNVPVLWYRNEVKLHVSRTVLMHVEGKKHRLEMRTVSLDDTC 1067 Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEI 1055 IK K + L V E F+ KLQDF EKD +L E+ S+ VVW + Sbjct: 1068 QIKAEAKGIYSVAQLTVVEGDAVFVVKLQDFAATEKDELLLSCEL-SKDVPVVWYHSEKE 1126 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115 I K + G R L ++ +G Y+C + +A V V +I+ L Sbjct: 1127 ITASKTVV-LKSEGTCRSLLLKRVEQSSKGTYTCDCGTDKTSAVVDVQARDVKIVRPLYG 1185 Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 ++ G A FE+E+++ D +W +G + S + + DG K L +Y+C + AGE Sbjct: 1186 VELFDGETARFEVEISEDDVRGQWKLNGDVLSRSPDVDIIEDGSKHTLILYNCRVAMAGE 1245 Query: 1176 YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235 + N+KC+A L V+E +NF L + + V +A VE+ W K Sbjct: 1246 VAYTAANAKCSAKLKVKELPLNFLTSLND-VQVYEKDEARFEVELSRPPKSFRWLKGSQE 1304 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 ++ EK+ LI + L+IR +D+ +Y D ++ KL Sbjct: 1305 LQSDEKYELIQEGHTYVLLIRSAIYEDEAKYMFEAEDKRTACKL 1348 Score = 174 bits (424), Expect = 2e-41 Identities = 118/387 (30%), Positives = 168/387 (43%), Gaps = 8/387 (2%) Query: 1585 KVGDEWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 + GD ++TA I G P P W K G + I T +S + IK R + +Y Sbjct: 8938 RAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRKDTGEY 8997 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 I ASN G V + V D P P GP+ IS E V + W P ++GG + Y + Sbjct: 8998 VITASNPFGVKEETVKVTVLDVPDSP-GPIECSGISSEKVALSWTAPTENGGSPIKYYTL 9056 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 EK E W + + D Y KL + EY FRV A N G SE SE + + Sbjct: 9057 EKRETSRLLWTVLEEKVVDCH-YVAYKLIQGNEYFFRVSAVNQYGASEPSHSEAVKMVDR 9115 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX 1822 P +D S +TW +GGS II Y VE K++ G +W Sbjct: 9116 FGPPGPPSKPEVEK-VDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRASKKSIA 9174 Query: 1823 XARIQK--LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 Q L+ + Y+FR++A N G P + PP P N ++++T Sbjct: 9175 ELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNPRITDTTKT 9234 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 + TL W +P NGG IT Y+IE K + W K + E + ++ + FRI Sbjct: 9235 TATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAKYHFRI 9294 Query: 1941 SAENTVGVSLPTE-SQSVRLEKHATVP 1966 SA N+ G P E S+ V + + A+ P Sbjct: 9295 SAVNSKGAGEPAETSELVEIIERASEP 9321 Score = 173 bits (421), Expect = 4e-41 Identities = 120/398 (30%), Positives = 183/398 (45%), Gaps = 27/398 (6%) Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 +I++ S + W+ P DDGG ++ Y +E+ E ++ V + +V T+ ++ L NCE Sbjct: 3997 DITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLSGE-NVLTHTVKDLYVNCE 4055 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX-------------IDNES 1783 Y FRV A N VG + LE VI + +P ++S Sbjct: 4056 YFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKS 4115 Query: 1784 VYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXX--XXXARIQKLSINTTYQFRIY 1840 + ITW + +GG PI Y VE I+++G +++ + L N YQFR+ Sbjct: 4116 ITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVR 4175 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N G S P S + + P P NF E + SV W PE +GGS I NY Sbjct: 4176 AENVAGVSEPSRSTQLLKAADPVDKPGAPINFTFDEIRNTSVICNWEPPEDDGGSEILNY 4235 Query: 1901 IIEFKTVKGK--SWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 I+E + K + W I T+ G + + + E E IFR++AEN G P S + Sbjct: 4236 ILEKRDYKKEEVGWITITSTLKG--NSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGPL 4293 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + P P P + V ++ SW P+ D G+P+LGY I ++V W V Sbjct: 4294 TAKNQFDPPDAPNTP-RVHEVTASTARLSWHEPK-DNGSPILGYWIERKEVNSKHWTRVN 4351 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEP 2052 + +N+L+ + +L E TY+ R+ A N G SEP Sbjct: 4352 RALINSLEVKVSNLMEGLTYIFRVCAENLAGPGPFSEP 4389 Score = 166 bits (404), Expect = 5e-39 Identities = 188/797 (23%), Positives = 305/797 (38%), Gaps = 58/797 (7%) Query: 1287 PPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 PP++ V ++ ++K G+ V L + P P W +K C+ + Sbjct: 8051 PPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPRVTWKRGDNSLKSCEGQVITHQRHHF 8110 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L + V G+Y + EN P P P++ + S+I++ W Sbjct: 8111 QLEMTAVTKEHTGVYTILAEN-------------ATPPGPIVNPSVTDTTYSTISLAWTA 8157 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 P N G S +I Y+VE + +T +WI +N+ +T IQNL + Y+ R AVN V Sbjct: 8158 PANDGGSPVIGYLVECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVG 8217 Query: 1461 ISDASETTEYYKVIKETKIQSPTV-EKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 S+ E + V K+ + V LK + + L G P+PK+TW + Sbjct: 8218 FSEPVEVPGKH-VAKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITWAKM 8276 Query: 1519 GKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDH---GEVETSCVVGIQQKPVI 1573 +K + + K I FN G + VV + P Sbjct: 8277 NTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYI-FNLESLAGMKMYTIVVKVYDTPGP 8335 Query: 1574 TISNEDIKQKHKVGDE--WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSV 1629 + N +K+ K G W G EV Y + K ++I + KTS Sbjct: 8336 PV-NLMVKETSKDGASIFWDSPLTDGGY---EVTHYIVEKRDTERKAWSIVSMNCNKTS- 8390 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--SRESVTIEW 1687 + +L S + + N G T +P + + + +++S TI W Sbjct: 8391 FEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMDFKTVLVTKDSCTISW 8450 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 K PL DGG + Y +E D+ K ++++ Y + L E EY +RV A N Sbjct: 8451 KKPLSDGGSRIISYVLEVLNGDDK--YKELMRSKNMQ-YSAKDLVEGKEYTYRVKAINDS 8507 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV--- 1804 G A E + + I E + P + +K Sbjct: 8508 GEGAAKELTVVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDD 8567 Query: 1805 -EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL 1863 ++K G+ I+ N ++ I RN G T ++ +GK Sbjct: 8568 EDLKDSGRVCAESSSVNTTLL-IRDCQRNDASKYTITLRNSAGIK-ESTIFIRV-VGKPG 8624 Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 P P F + T+ TLKW P+ +GGS I NYI+E + W VTV SV Sbjct: 8625 IPVG-PIKF--KDVTADGATLKWGAPKDDGGSDIANYILEKRDSVTNMW---VTVSSSVE 8678 Query: 1924 EHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 + + + E E IFR+ AEN GV +S + + VP P P +I + N Sbjct: 8679 TNSMRVTGLHEGTEYIFRVCAENKYGVGEGLKSDPIIAKHPFNVPEAPPPP-QIMNMQHN 8737 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 +W P GG+P+ GY++ ++ +W + + ++ L+E Y R+ Sbjct: 8738 SAYLAWLDPRKTGGSPITGYHLEFKERNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRV 8797 Query: 2042 YARNEIGLSEPLESDEP 2058 A N G+ +P +P Sbjct: 8798 MAINLAGIGKPSAPTDP 8814 Score = 163 bits (397), Expect = 4e-38 Identities = 177/759 (23%), Positives = 320/759 (42%), Gaps = 68/759 (8%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENN--CGHADVEMNVTI---LDKPSPPGKPNILEIDSS 1395 K S + K+ I+++ EN CG + +T D P P P + E+ +S Sbjct: 4257 KGNSFPVTKLIEGKEYIFRVTAENKFGCGPPCISGPLTAKNQFDPPDAPNTPRVHEVTAS 4316 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453 + + W EP++ G S I+ Y +E +E+++ W V I + + NL +Y FR Sbjct: 4317 TARLSWHEPKDNG-SPILGYWIERKEVNSKHWTRVNRALINSLEVKVSNLMEGLTYIFRV 4375 Query: 1454 YAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 A N S+ S+ T I +P + K+ + L G + Sbjct: 4376 CAENLAGPGPFSEPSDRTTAMDAILPPGPPTPWIVDTGKDFVIVAWKP-PLYNGGGDILG 4434 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY-KCIAFNDHGE-----VETSCV 1564 V G+K T + + Y + +A ND G E V Sbjct: 4435 YHVEKVLAGEKEWTRSTEFRCKDLTFTVTGLIEGADYYIRVVAINDAGPGAPGVTEPVMV 4494 Query: 1565 VGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 Q+ PV+ + +K+ + G+ + AV+ G P PEV W K+ +++ D+ + Sbjct: 4495 KEPQESPVVEF-DASVKKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMI-VE 4552 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE---IS 1679 T+ K S + IK+ R+ KY I +N++GT S E + + D P GPV+ + ++ Sbjct: 4553 TEGKNSSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVP----GPVVDLKTVTVT 4608 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYM 1738 ++++T+ W P D+GG ++ Y + + + + + C IQ L EY Sbjct: 4609 KKNITLTWSDPHDNGGSDIIGYDVLRKDAKMKLFRHPMET---ASCKCDIQGLLAGEEYD 4665 Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 FRVIA+N G + PI+ + PS ++ + W P +GGSP Sbjct: 4666 FRVIARNKYGDGAPSDLGPILAQDPKGTPSAPEKLHYTDR-GKTTIMLAWQPPRTDGGSP 4724 Query: 1799 IIDYKVE-IKQEGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTS-- 1853 I Y VE ++ + +++ I+ LS N YQFR+ A NE+G P + Sbjct: 4725 IRGYYVEKMRSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAIT 4784 Query: 1854 ----DDKITIGKTLTPPSQPRNFVVSESTSRSV----------TLKWTEPESNGGSPITN 1899 DD++ T+ + ++ + ++ + +L+W + + +P+ + Sbjct: 4785 AKIQDDELAPVITILKFFKSNAIIIKKGSAIDIPAEVKGLPLPSLQWVKDDVVIETPVED 4844 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 +I +T + T + I +D+ +++ AEN G ++Q V Sbjct: 4845 KMI-METEEMDRTTLRTKI-------AIPETVRQDKGNYKLVAENCFG-----KAQHVIR 4891 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW-MEVGK 2018 + P PP + + + +T W PE +GG+ + Y I RD +K EV Sbjct: 4892 VEILDRPLPPRNVVVSDIKADSCYLT-WDVPEDNGGSEITNYIIERRDASKKKSDFEVQT 4950 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 ++ ++ + L+ N Y RI A N+ G+S+ +S++ Sbjct: 4951 TNLIDRRYGVYKLNVNGAYQFRIKAENKYGISDGCDSEK 4989 Score = 163 bits (397), Expect = 4e-38 Identities = 159/596 (26%), Positives = 242/596 (40%), Gaps = 43/596 (7%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G + ++ P P+ W + + K S++L IK G+Y Sbjct: 5757 VHAGGVIRIIAYVSGQPTPDITWSRDGSALPP--EAKVETTFISSALIIKPCSRKHLGVY 5814 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVV 1417 L +N G + V +LD P P G P E + + S + W PEN G S I Y+V Sbjct: 5815 TLTAKNAGGEKKKNVTVEVLDVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIV 5874 Query: 1418 EYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 E +E + W SV ++T L + SY FR A N + I ET VI+E Sbjct: 5875 EKREAERKAWTSVSFTASRTNAVAHGLTSGKSYFFRVAAENAIGIGPFVETAAEV-VIRE 5933 Query: 1477 T--------KIQSPTVEKPLKNITTEPNED---IELTC-IFGGVPQPKVTWYRDGK-KLK 1523 +++ V K L ++T +P + E+T I K + R K KL Sbjct: 5934 PISIPERPEELEVHKVTKDLISVTWKPPKSDGGSEITMYILEARMIGKDKFTRLTKEKLL 5993 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVVGIQQK-----PVITISN 1577 K TY+ ++ IA N+ G + S C I K P I + Sbjct: 5994 ERKYTYDG--------LREGDTYEFRVIAVNEVGPGKPSFCTKPITCKDELEPPTIELDF 6045 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 D K +VG+ L+ G PPP + WY++ +++ DK T + + + +R Sbjct: 6046 RD-KIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTLTTMSLGLMKAQR 6104 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 HS +Y + N+ G+ + V P PE P + RE+ + + W P DGG Sbjct: 6105 EHSGRYVVVVENSTGSRKGICNVTVVGVPEAPEMPTV-REVYATNALVLWNRP-RDGGKP 6162 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE-S 1755 +T Y +EK E RW + T + +Q L E CEY FRV+A+N +G + E S Sbjct: 6163 ITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAENELGTGDPSEPS 6222 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814 +PI+ K + PS +SV + W +G I Y VE K+ G +W Sbjct: 6223 KPILAKDPIVCPSPPVTPEAYDK-TKDSVSLKWKLPRHDGKGRIFGYLVEYKKPGAVEWI 6281 Query: 1815 XXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 + L+ Y FRI+ N G S P + I + L P Sbjct: 6282 QANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIKVHDRLEKP 6337 Score = 162 bits (394), Expect = 8e-38 Identities = 117/463 (25%), Positives = 209/463 (45%), Gaps = 12/463 (2%) Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 F+ +++TVKE+ T + ++ + S+ WY+N+ + PS+ I + G+ + T Sbjct: 1396 FVKPIKDVTVKERETAEFSVELSHENI-SVVWYKNDIRLHPSKVIHMSDHGK----IHTL 1450 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 E+ D + + K+ A +T+ + F LQ +Y E V L C+ S Sbjct: 1451 AFKEVSIDDTSMIKVEAMDKTV-TAMLTVIEGDLYFTTKLQ-NYTAVEKDEVKLRCELSK 1508 Query: 955 TV-STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 + KW+ + KE++ + II +G+ ++G C +T+ L ++ Sbjct: 1509 AIGDVKWFKDGKELTPSKNIAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIE 1568 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 E + +R L EV E + A E EI+ + W+ GE ++ + + ++ G Sbjct: 1569 ERDIKIVRPLYSVEVTETETAKFETEISEDDVHGNWKLKGEALQQSAD-VEMKEEGTRHM 1627 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG 1133 L + N + G + +A++ V ++ L++ V G ATFE EL+ Sbjct: 1628 LVLYNVHMDMAGAVDFSAANARSSAQLRVKARSVGLVRPLKDVMVTAGETATFECELSYE 1687 Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 +V WF G +++ ++ + G+ L I D +L +AGE + + A L V+E Sbjct: 1688 GIVVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTAKDFQTQAHLIVKE 1747 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 P + FT L E V ++ L + E +V W++ + T+KF L+S KR L Sbjct: 1748 PPVEFTKPL-EDQTVEEDSTVTLECAVSRENAEVRWFRDGQELRKTKKFDLLSLGCKRML 1806 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYE 1294 +I C+ +D YTC D K++ L V VEF + D E Sbjct: 1807 VIHNCSSEDIKMYTCDTKDFKTSCYLDVTPPHVEFTKLLQDVE 1849 Score = 161 bits (390), Expect = 3e-37 Identities = 108/399 (27%), Positives = 179/399 (44%), Gaps = 17/399 (4%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G + V AV+ G P P W + + + + V+ IK++ R+ S +Y+ Sbjct: 7673 RAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGNLCVLIIKDVSRTDSGEYS 7732 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + A N++ + + + + D P PEGPV + +I ++ ++ W PL+DGG +T Y +E Sbjct: 7733 LVAENSSSKVTQALKIVIRDIPGPPEGPVEISDIDSDACSLSWNKPLEDGGSNITNYVVE 7792 Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 K + W V V +T C + KL EY+FR+ A+N G S+ ++S+ +V K Sbjct: 7793 KCDVSRGDW--VTAVSSVSKTSCRLGKLIPGKEYVFRIRAENRFGLSDPIQSDRMVAKFP 7850 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW---KXXXXXX 1820 P + + +++ W +GGSPI Y +E K+ + Sbjct: 7851 FGEP----LNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIERKERNSLFFVKANDTIVR 7906 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 L Y F++ A N S P + +T + P +P V + T Sbjct: 7907 TTQYPCAGLIKGLEYTFKVSAINRACQSKPSANTYFVTARTPVYTPGKPE---VLDITKN 7963 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV--HEHCIENIKEKDEIIF 1938 SVTL WT P+++GGS I Y +E V G SW + T +V E+ + ++ F Sbjct: 7964 SVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQF 8023 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 R+ A+ V +S P+E L V PP L +RM Sbjct: 8024 RVIAKTAVNISKPSEPTDPVLVCAENV--PPRLDLNVRM 8060 Score = 156 bits (379), Expect = 5e-36 Identities = 122/469 (26%), Positives = 216/469 (46%), Gaps = 19/469 (4%) Query: 830 AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886 A P F+ + Q+I ++E +I V +P +IT W ++ + DG+ Sbjct: 531 AVPLKFVKKLQDIVLQEAESIGSSAVFECQISPSTAITSWMKDGGNLREGPKYKFTADGK 590 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 + +L I +V D+G+Y CVA N+ + + A++ ++ V +VK L+ +G+ + Sbjct: 591 DRKLNILDVQLS-DTGEYTCVARNAGKEITCTAKLIVEELPVKWVKELEPETTCMKGQPM 649 Query: 947 ILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 L C+ + W N + + I G D G C V+ +E Sbjct: 650 YLTCELNKERDVTWKRNGAVLKKKAGKVAINIIGLQHAVTIQNATEEDTGAYTCEVEGRE 709 Query: 1006 ---TSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 T+T + V E I +++ K L+D VK K A + E+ +T + W + I P + Sbjct: 710 DISTTTNVKVLEIIKDWLVKPLRDQHVKPKSKATFKGELFKDTPNWKWLKGETEITPSE- 768 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--------VELPPEIITRL 1113 K + K G L I N D EY+ + D TA++T+ E EI+ L Sbjct: 769 KMEIAKDGANVTLTINNCQPDDVSEYTIEVEDRRYTAKLTLGGAVRRRFQEREAEILKPL 828 Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 + +V + +A F+ E+++ D + W G + S + ++G+K+ L + + +D A Sbjct: 829 ASLEVVEKEEANFDTEISEEDIIGEWKLRGQVLTRSPTCDIKLEGRKRFLTLKNVQVDQA 888 Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 GE S + N+ T +LTV+E + F L + + VP A + E V W+K Sbjct: 889 GEVSYQALNAVTTGMLTVKELEMGFVDPLKD-VSVPEKKQAKFECTVTKEVPKVMWFKGA 947 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 ++ K+ +I D K L+I C DD+ +YT +L +S+++L+VE Sbjct: 948 EIVTPGPKYEIIDDGLKHMLVINSCEFDDEAQYTIEVLGQRSSSQLRVE 996 Score = 155 bits (376), Expect = 1e-35 Identities = 130/502 (25%), Positives = 201/502 (40%), Gaps = 20/502 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P P W +L D+ ++ TK + + + R YT++ N + S Sbjct: 2883 ITGYPTPVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLENDISSVS 2942 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 EV + V PS P+ + E+SR V + W+ P DGG +T Y IEK E W+K Sbjct: 2943 GEVEVNVIACPSAPKDFKVA-EVSRHHVHLMWEAPEHDGGSPVTHYQIEKREVSRKTWVK 3001 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXX 1774 VA D+E + + + E EY+F V A N G E A EP+ I + VP Sbjct: 3002 VASGVLDLE-HTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLK 3060 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK-XXXXXXXXXARIQKLSIN 1832 +S+++ W P + +GGSP+ Y V+ Q G KW+ ++ L Sbjct: 3061 WRDKC-AKSIFLLWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQVSGLLEG 3119 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 Y +R+ A N++G S P + D I PP + + + K P Sbjct: 3120 QWYSYRVRAFNKLGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADV 3179 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLP 1951 G P + ++ ++ H I N D + I A N G + Sbjct: 3180 KGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATA 3239 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 T ++ L+K P PP A +I + S +W P DGG+P+ Y + R K Sbjct: 3240 TIDVNI-LDK----PGPPAA-FDISEITSESCCLAWNPPRDDGGSPITNYIVESRQTDKE 3293 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071 W+++ V F L+ Y+ RI A N+ G+ EP E +P ++ + Sbjct: 3294 EWIKL-SATVKHTTFKACKLTGMKEYIFRISAENQFGIGEPAEH------VPIVAKYSFD 3346 Query: 2072 EPGEQTEVXXXXXXXXXXXXXW 2093 PG T V W Sbjct: 3347 PPGSPTRVTPSDITKDAVTLTW 3368 Score = 153 bits (371), Expect = 5e-35 Identities = 103/383 (26%), Positives = 160/383 (41%), Gaps = 10/383 (2%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 I D K G +++ + P E W+ L NI T + R+K Sbjct: 2468 IKTTDQKLVTDAGKPFIMRVPYDAYPRAEAEWFFEDTSLPVQ---NIDTSVDKTEYRLKS 2524 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 + +Y + SN G + + L V D P + ++ E V++ W+ P DG Sbjct: 2525 PSKEDQGQYKVVISNKHGAAEAFIVLDVIDVPGSVKNLRVLDTADGE-VSLAWEEPESDG 2583 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 G ++ Y +E+ + W D D YC+ L+++ Y+FRV A+N VG A+ Sbjct: 2584 GSKIIAYVVERRDVKRKTWALATD-RADTPEYCVTGLHKDSAYLFRVCARNRVGSGPAVV 2642 Query: 1755 SEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812 +E V K DVP ++ I+W P + +GGS I Y +E++ K Sbjct: 2643 TEDAVQAKNKFDVPDAPEDVAVET-VNKFGATISWKPPKFDGGSEITAYVIELRDRTSVK 2701 Query: 1813 WKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 W+ A + + N Y FR+ A N G P + + + I + PS P Sbjct: 2702 WEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIERPSPPL 2761 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 N S+ +VTL W P SNGGS IT YIIE W + + + + Sbjct: 2762 NLNFSDQIKTAVTLTWETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLSYRVSGL 2821 Query: 1931 KEKDEIIFRISAENTVGVSLPTE 1953 K ++R+ AEN GVS P + Sbjct: 2822 KPGQNYLYRVCAENAAGVSDPVQ 2844 Score = 151 bits (366), Expect = 2e-34 Identities = 166/744 (22%), Positives = 288/744 (38%), Gaps = 47/744 (6%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTILD---KPSPPGKPNILEIDSSSI 1397 S T+ V I+++R EN G + V I+D +PSPP N + +++ Sbjct: 2714 SATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIERPSPPLNLNFSDQIKTAV 2773 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYA 1455 + W+ P + G S I Y++E E T +W+ + + + LK +Y +R A Sbjct: 2774 TLTWETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDLSYRVSGLKPGQNYLYRVCA 2833 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVE-----KPLKNITTEPNEDIELTCIFGGVPQ 1510 N +SD + + ++ + PT + K L+ I +P + + G P Sbjct: 2834 ENAAGVSDPVQ--QLGPLLADDPHVGPTFDLSGFRKGLEVIVPQP---LTIRVPITGYPT 2888 Query: 1511 PKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 P W K+L + + T Y ND V V Sbjct: 2889 PVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLENDISSVSGEVEVN 2948 Query: 1567 IQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTK 1624 + P + + +H V W G P V Y+ + + K + + + Sbjct: 2949 VIACPSAPKDFKVAEVSRHHVHLMWEAPEHDGGSP---VTHYQIEKREVSRKTWVKVASG 3005 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSS---VEVTLKVYDKPSKPEGPVIM--REIS 1679 + ++ + +++ A N G ++ + + + P+ P + R+ Sbjct: 3006 VLDLEHTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDPPENLKWRDKC 3065 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 +S+ + W+PP DGG + Y ++K + ++W D +++ + L E Y + Sbjct: 3066 AKSIFLLWEPPKYDGGSPVKGYVVDKCQRGTDKWEPCGDPLPELKLQ-VSGLLEGQWYSY 3124 Query: 1740 RVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG-S 1797 RV A N +G S + ++ I A + P + + P++ G + Sbjct: 3125 RVRAFNKLGASRPSRATDDIQAVDAREPPEIQLDVKLLAGLTARAGTKIELPADVKGKPA 3184 Query: 1798 PIIDY-KVE-IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 P + + K + + + + I + T + I A N G + T D Sbjct: 3185 PRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYIIEAVNVCGRATA-TIDV 3243 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 I L P P F +SE TS S L W P +GGSPITNYI+E + + W K+ Sbjct: 3244 NI-----LDKPGPPAAFDISEITSESCCLAWNPPRDDGGSPITNYIVESRQTDKEEWIKL 3298 Query: 1916 -VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 TV + + C + E IFRISAEN G+ P E + + P PT Sbjct: 3299 SATVKHTTFKAC--KLTGMKEYIFRISAENQFGIGEPAEHVPIVAKYSFDPPGSPTRVTP 3356 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 + + +T W P+ DGG+P+ GY + D W+ K+ V F ++ L Sbjct: 3357 SDITKDAVTLT-WFEPDEDGGSPITGYWVEKFDPESEKWIRCNKLPVKDTSFRVKGLRTK 3415 Query: 2035 HTYMIRIYARNEIGLSEPLESDEP 2058 Y R+ A N G + +P Sbjct: 3416 KKYRFRVLAENLAGPGKASSETDP 3439 Score = 142 bits (345), Expect = 7e-32 Identities = 92/302 (30%), Positives = 141/302 (46%), Gaps = 10/302 (3%) Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK----XXX 1817 T LD+P + + + I W + +GG+PI +Y VE K K W+ Sbjct: 6600 TVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVKKPWEPWSVVSS 6659 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL-TPPSQPRNFVVSE 1876 A++ +L Y R+ A N+IG S S TI K + PP P V S+ Sbjct: 6660 SGTNTKAKVSRLEKGREYVVRVRAENKIGISTGLESPP--TIAKHMFNPPGPPGLPVCSD 6717 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936 T +VT++WT P+ +GGSPI+ Y+IE + + GK W ++ + + + E + Sbjct: 6718 ITENAVTVEWTLPDYDGGSPISGYVIERREMTGK-WIRVNKTPVLDLRYRVSGLFEGNSY 6776 Query: 1937 IFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 FR+ AEN G+S P+ S V+ + T P PP P ++R + W P DGG Sbjct: 6777 EFRVFAENIAGISDPSLASDPVKAARAITRPGPPGNP-KLRDWSKSYADICWTKPTRDGG 6835 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 +P+LGY + + W + K + + + L E Y RI A N++G SEP E Sbjct: 6836 SPVLGYVVEAQKSGSAQWDRINKDLIKICAYRVPGLIEGMEYRFRIRAANKVGESEPREL 6895 Query: 2056 DE 2057 E Sbjct: 6896 AE 6897 Score = 139 bits (337), Expect = 7e-31 Identities = 151/686 (22%), Positives = 283/686 (41%), Gaps = 46/686 (6%) Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 EF++ ++D VKE++ A VE++ E VVW ++ + P K + G I L + Sbjct: 1395 EFVKPIKDVTVKERETAEFSVELSHENISVVWYKNDIRLHPSKVIH-MSDHGKIHTLAFK 1453 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 S+ D D++ TA +TV+E T+LQN + ++ EL+K V Sbjct: 1454 EVSIDDTSMIKVEAMDKTVTAMLTVIEGDLYFTTKLQNYTAVEKDEVKLRCELSKAIGDV 1513 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 +WFKDG E+ S +I + DGKK+ L + + + GEY+C+ G+ K TA L +EE I Sbjct: 1514 KWFKDGKELTPSKNIAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIEERDIK 1573 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 L + T + T EI ++ + W K ++ + + + + L++ Sbjct: 1574 IVRPLYSVEVTETETAKFET-EISEDDVHGNWKLKGEALQQSADVEMKEEGTRHMLVLYN 1632 Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 D +A+S+ +L+V+ +V ++ + G T + ++ Sbjct: 1633 VHMDMAGAVDFSAANARSSAQLRVKARSV--GLVRPLKDVMVTAGETATFECEL-SYEGI 1689 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 EW + + ++ + K + ++ +LTI+ V ++AG KL ++ A + + Sbjct: 1690 VVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGEVKLTAKDFQTQAHLIVKEPP 1749 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKT 1436 ++ + P + +E DS+ C EN + + + QE+ T+ + ++ K Sbjct: 1750 VEF-TKPLEDQTVEEDSTVTLECAVSRENAE----VRWFRDGQELRKTKKFDLLSLGCKR 1804 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 I N SS + Y + D T Y + ++ K L+++ Sbjct: 1805 MLVIHNC---SSEDIKMYTCDTKDFK-----TSCYLDVTPPHVE---FTKLLQDVEVRER 1853 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 E + C KV W++DG +++ K YE +K F+D Sbjct: 1854 EAAKFECEVSR-ESAKVRWFKDGSEIRKGK-KYE-----ITASGVQRTLIIHKS-GFDDE 1905 Query: 1557 GEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI-----PPPEVIWYKNG 1610 E E + ++T+ E K K+ E + T ++ I EV WY+ Sbjct: 1906 AEYECDARTS-KTSGLLTVIEEAPKFTKNLSNVEGMETDSVKMICEVSKASAEVTWYRGE 1964 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV----EVTLKVYDKP 1666 +L Y + ++ IK L+ + +YT S TS+V E+ + +P Sbjct: 1965 EELPEVGRYEQIMDGRKRILIIKGLRMEDAGQYTCRLSPNIKTSAVLQLNELAAEFISRP 2024 Query: 1667 SKPE-----GPVIMREISRESVTIEW 1687 E +S+E+ ++W Sbjct: 2025 QNQEVVEGQAAEFTCSVSKETYEVKW 2050 Score = 139 bits (336), Expect = 9e-31 Identities = 123/574 (21%), Positives = 227/574 (39%), Gaps = 23/574 (4%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547 LK+ T ED + TC + V WY++G++++ + R Sbjct: 2295 LKDQTVTEFEDADFTCKLNK-EKASVKWYKNGREIREGPRYHMQREGKVCRLIIKECRPD 2353 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 +C E T + +++ PV I + D +V V EV W Sbjct: 2354 DECEYACGMDERRTRARLFVEETPVEIIRPPQDMLEPPASD--IVFEVELNKDRVEVKWM 2411 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +N + +Y + ++ K +++ E++ +Y I A + + +E+ K + Sbjct: 2412 RNNMIIVQGDKYQMISEGKIHRLQVCEIRPRDQGEYRIVAKDKDARAKLELAAVPKIKTT 2471 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 + ++ + + + + P D ++ E D + ++ D D Y Sbjct: 2472 DQK---LVTDAGKPFIM---RVPYDAYPRAEAEWFFE----DTSLPVQNIDTSVDKTEYR 2521 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 ++ ++ + ++V+ N G +EA ++ +DVP D E V + Sbjct: 2522 LKSPSKEDQGQYKVVISNKHGAAEAF-----IVLDVIDVPGSVKNLRVLDTADGE-VSLA 2575 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEI 1845 W E +GGS II Y VE + +K W + L ++ Y FR+ ARN + Sbjct: 2576 WEEPESDGGSKIIAYVVERRDVKRKTWALATDRADTPEYCVTGLHKDSAYLFRVCARNRV 2635 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 G+ ++D + P P + V T+ W P+ +GGS IT Y+IE + Sbjct: 2636 GSGPAVVTEDAVQAKNKFDVPDAPEDVAVETVNKFGATISWKPPKFDGGSEITAYVIELR 2695 Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHAT 1964 W + + ++ E E IFR+ AEN GV P+ + + V++ Sbjct: 2696 DRTSVKWEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIMDPIE 2755 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024 PSPP + + + +T W TP +GG+ + GY I + W+ L Sbjct: 2756 RPSPPLNLNFSDQIKTAVTLT-WETPVSNGGSMITGYIIEKCEDGTDKWLRCNARLCPDL 2814 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + L Y+ R+ A N G+S+P++ P Sbjct: 2815 SYRVSGLKPGQNYLYRVCAENAAGVSDPVQQLGP 2848 Score = 138 bits (335), Expect = 1e-30 Identities = 212/935 (22%), Positives = 372/935 (39%), Gaps = 93/935 (9%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK 1250 E P + F + + +++ A L + +V W K + I D ++ + ++ K Sbjct: 4499 ESPVVEFDASVKKGVIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEI-DKDRMIVETEGKN 4557 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 +L I+K T D +Y ++ T + +V++++ P +VD + K+ ++TL Sbjct: 4558 SSLFIKKTTRTDHGKYKISGTNSSGTKSAETRVDIMDVPGPVVDLKTVTVTKK--NITL- 4614 Query: 1309 VDYQAFPQPNDEW---IVNSKIIKK---CKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 + P+D I+ +++K K + +++ S I+ + + +++ Sbjct: 4615 ----TWSDPHDNGGSDIIGYDVLRKDAKMKLFRHPMETASCKCDIQGLLAGEEYDFRVIA 4670 Query: 1363 ENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 N G IL + PS P K + + ++I + W P G S I Y V Sbjct: 4671 RNKYGDGAPSDLGPILAQDPKGTPSAPEKLHYTDRGKTTIMLAWQPPRTDGGSPIRGYYV 4730 Query: 1418 EYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 E D+ E+ + K T+ +I+NL N Y+FR AVNEV + S+ K+ Sbjct: 4731 EKMRSDSNEFEVANRKIFTECCGTIENLSENQEYQFRVKAVNEVGDGEPSKAITA-KIQD 4789 Query: 1476 ETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE 1530 + T+ K K+ I + I++ G+P P + W +D ++T K E Sbjct: 4790 DELAPVITILKFFKSNAIIIKKGSAIDIPAEVKGLPLPSLQWVKDDVVIETPVEDKMIME 4849 Query: 1531 N--------RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582 R YK +A N G+ + V I +P+ + Sbjct: 4850 TEEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFGKAQHVIRVEILDRPLPP--RNVVVS 4907 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWY----KNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 K +L V E E+ Y ++ +K ++D E TT + +L + Sbjct: 4908 DIKADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQ-TTNLIDRRYGVYKLNVN 4966 Query: 1639 HSSKYTIEASNTAGTS----SVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 + ++ I+A N G S S +V L + P P P I+ + ++T+ W PPLD+ Sbjct: 4967 GAYQFRIKAENKYGISDGCDSEKVQLSDPFGLPGPPRNPKIIAATAT-TMTLTWDPPLDN 5025 Query: 1694 GGLELTKYAIEKHEPDNNRWIKV--ADVDRDVET---YCIQKLNENCEYMFRVIAQNPVG 1748 GG + Y +EK E W +V A V + Y + KL E EY FR+ A N G Sbjct: 5026 GGSTIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAG 5085 Query: 1749 FSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 E SE + PS N S+ ++W P +K+GGSP+ Y +E+ Sbjct: 5086 VGPPSEASECRFAVDPCNPPSSPGAPEVKDKTKN-SITLSWSPPDKDGGSPVKGYIIEVH 5144 Query: 1808 QEG-KKWKXXXXXXXXXAR----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT---- 1858 +EG W+ + L +FRIYA N G S P + + +T Sbjct: 5145 EEGCPDWRRVNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAEILTQDIL 5204 Query: 1859 IGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESN-----GGSPITNYIIEFKTVKGKS 1911 I T+T + + ++ST R P G+ T + + S Sbjct: 5205 IEPTVTLDVSAHDLLNCRADSTIRIPATITGRPLPKVTWTFDGTAETEKKNDLHILPVDS 5264 Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRI-SAENTVGVSLPTESQS------VRLEKHA- 1963 + ++G ++ + +++ + F+I S++ T V++P + + E A Sbjct: 5265 EVRPFSLGELIYHNAFKSLTLFPHVSFQIHSSDTTSVVTIPISKLAHSGRYIINAESPAG 5324 Query: 1964 --------TVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 TV P P ++++ V +W P+ DGG + Y I + V W Sbjct: 5325 HKVVKVRVTVLDLPGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIEKKTVHGKAW 5384 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 +V + DL+ Y+ RI A N G Sbjct: 5385 TKVNPA-CAAQSLVVPDLNNGQEYLFRIRAENRFG 5418 Score = 138 bits (335), Expect = 1e-30 Identities = 126/512 (24%), Positives = 197/512 (38%), Gaps = 31/512 (6%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 LD PGKP ++ I S++ + W EP+ G + Y++E +++ + W+ N+ + Sbjct: 8818 LDPIDVPGKPEVISITKSTVTLQWIEPQFDGGHRLTGYIIEKRDLPSKIWMKANNVNVLE 8877 Query: 1438 T--SIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTV---EKPLKNI 1491 ++ +L+ Y FR A N IS ASE T+ +I + +PT+ + + + Sbjct: 8878 PAFTVMDLQEGCKYEFRIRAKNAAGAISPASEQTD--TIICRDEYAAPTIVIDAQVKEGL 8935 Query: 1492 TTEPNEDIELTCI-FGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXX 1546 T + I +T G P P W + GK K + T Sbjct: 8936 TVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRKDTG 8995 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y A N G E + V + P I I + KV W G P Sbjct: 8996 EYVITASNPFGVKEETVKVTVLDVPDSPGPIECSGISSE-KVALSWTAPTENGGSP---- 9050 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY--TIEASNTAGTS--SVEVTL 1660 I Y K E + +EK K ++Y + A N G S S + Sbjct: 9051 IKYYTLEKRETSRLLWTVLEEKVVDCHYVAYKLIQGNEYFFRVSAVNQYGASEPSHSEAV 9110 Query: 1661 KVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 K+ D+ P P P + ++ S T+ W+ P DDGG ++ Y +EK E RW++ + Sbjct: 9111 KMVDRFGPPGPPSKPEV-EKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRAS 9169 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 + + L E+ EY FRV A+N GF E E V A+ P Sbjct: 9170 KKSIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNPRIT 9229 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTT 1834 + + W NGG I Y +E K+EG + W + +L Sbjct: 9230 DTTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAK 9289 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 Y FRI A N G P + + + I + + P Sbjct: 9290 YHFRISAVNSKGAGEPAETSELVEIIERASEP 9321 Score = 136 bits (328), Expect = 8e-30 Identities = 183/847 (21%), Positives = 315/847 (37%), Gaps = 63/847 (7%) Query: 524 GSTVQFECQVEGYPRPQIT-WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 GS+ FECQ+ P IT W + ++ ++ D + L I +V D G +T Sbjct: 552 GSSAVFECQIS--PSTAITSWMKDGGNLREGPKYKFTADGKD-RKLNILDVQLSDTGEYT 608 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 CVA+NA + T +LIVE E+ V + E P T K + Sbjct: 609 CVARNAGKEITCTAKLIVE--------ELPVKW------------VKELEPETTCMKGQP 648 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYCSVLKITNVK 701 Y L C L E D+ W G + +++ I H + I N Sbjct: 649 MY--------LTCEL--NKERDVTWKRNGAVLKKKAGKVAINIIGLQH----AVTIQNAT 694 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + G YT EG + +K E +++PL+ V+ ++ Sbjct: 695 EEDTGAYTCEV---EGREDISTTTNVKVLEIIKDWLVKPLRDQHVKPKSKATFKGELF-K 750 Query: 762 PRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P W K P + + DG ++TI + D YT++ E+ A+ + Sbjct: 751 DTPNWKWLKGETEITPSEKMEIAKDGANVTLTI-NNCQPDDVSEYTIEVEDRRYTAKLTL 809 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 V +E + + V EK ++ + W ++++ S T Sbjct: 810 GGAVRRRFQEREAE--ILKPLASLEVVEKEEANFDTEISEEDIIG-EWKLRGQVLTRSPT 866 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 +G L + NV + +G+ A N+ +T+ ++ FV L K Sbjct: 867 CDIKLEGRKRFLTLKNVQVD-QAGEVSYQALNAVTT----GMLTVKELEMGFVDPL-KDV 920 Query: 939 ETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 E K EC T W+ + ++ EII +G D Sbjct: 921 SVPEKKQAKFECTVTKEVPKVMWFKGAEIVTPGPKYEIIDDGLKHMLVINSCEFDDEAQY 980 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 V Q +S+ L V+ F++ LQD VKE A E+E+ + V+W R+ E+ Sbjct: 981 TIEVLGQRSSSQLRVEGIRLNFVQPLQDQTVKEGKTAHFELELTHDNVPVLWYRN-EVKL 1039 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 G +L +R S+ D + + A++TVVE + +LQ+ Sbjct: 1040 HVSRTVLMHVEGKKHRLEMRTVSLDDTCQIKAEAKGIYSVAQLTVVEGDAVFVVKLQDFA 1099 Query: 1118 VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 + ++ EL+K D V W+ EI S + L +G + L + + G Y+ Sbjct: 1100 ATEKDELLLSCELSK-DVPVVWYHSEKEITASKTVVLKSEGTCRSLLLKRVEQSSKGTYT 1158 Query: 1178 CEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237 C+ G K +A++ V+ + L L T A VEI ++ + W V+ Sbjct: 1159 CDCGTDKTSAVVDVQARDVKIVRPLYGVELFDGET-ARFEVEISEDDVRGQWKLNGDVLS 1217 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297 + +I D K TLI+ C E +AK + KLKV+ E P + + Sbjct: 1218 RSPDVDIIEDGSKHTLILYNCRVAMAGEVAYTAANAKCSAKLKVK--ELPLNFLTSLNDV 1275 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 ++ + V+ P + W+ S+ ++ + + + + L I+ D Sbjct: 1276 QVYEKDEARFEVELSR-PPKSFRWLKGSQELQSDEKYELIQEGHTYVLLIRSAIYEDEAK 1334 Query: 1358 YKLRLEN 1364 Y E+ Sbjct: 1335 YMFEAED 1341 Score = 135 bits (326), Expect = 1e-29 Identities = 126/504 (25%), Positives = 213/504 (42%), Gaps = 31/504 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMIVRQGE 750 +K+ K+F T V V++ GE S + + TG ++ ++PLK + V + + Sbjct: 869 IKLEGRKRFL--TLKNVQVDQAGEVSYQALNAVTTGMLTVKELEMGFVDPLKDVSVPEKK 926 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKA 807 V P + W K + V P DG H + ++ + DE YT+ Sbjct: 927 QAKFECTVTKEV-PKVMWFKGAEIVTPGPKYEIIDDGLKHML-VINSCEFDDEAQYTI-- 982 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 E + + S+ E N F+ Q+ TVKE T +T + VP + WY Sbjct: 983 ---EVLGQRSSSQLRVEGIRLN-----FVQPLQDQTVKEGKTAHFELELTHDNVP-VLWY 1033 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 RN + S T+ + +G+ L + V S D C A A++T+ Sbjct: 1034 RNEVKLHVSRTVLMHVEGKKHRLEMRTV-----SLDDTCQIKAEAKGIYSVAQLTVVEGD 1088 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 FV LQ TE+ + ++L C+ S V WYH++KEI+ + EG Sbjct: 1089 AVFVVKLQDFAATEKDE-LLLSCELSKDVPVVWYHSEKEITASKTVVLKSEGTCRSLLLK 1147 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 G C +TS ++ V+ + +R L E+ + + A EVEI+ + Sbjct: 1148 RVEQSSKGTYTCDCGTDKTSAVVDVQARDVKIVRPLYGVELFDGETARFEVEISEDDVRG 1207 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W+ +G+++ + D + G L + N V GE + + C+A++ V ELP Sbjct: 1208 QWKLNGDVLS-RSPDVDIIEDGSKHTLILYNCRVAMAGEVAYTAANAKCSAKLKVKELPL 1266 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 +T L + +V + ++A FE+EL++ RW K E+Q +L +G L I Sbjct: 1267 NFLTSLNDVQVYEKDEARFEVELSRPPKSFRWLKGSQELQSDEKYELIQEGHTYVLLIRS 1326 Query: 1168 CDLDDAGEYSCEVGNSK--CTAIL 1189 +D +Y E + + C IL Sbjct: 1327 AIYEDEAKYMFEAEDKRTACKLIL 1350 Score = 132 bits (320), Expect = 8e-29 Identities = 182/828 (21%), Positives = 319/828 (38%), Gaps = 53/828 (6%) Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 ++ FVK + K +E +T + SH +S WY N + + G+ Sbjct: 1393 RLEFVKPI-KDVTVKERETAEFSVELSHENISVVWYKNDIRLHPSKVIHMSDHGKIHTLA 1451 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D +IK D+ + ML V E F KLQ++ EKD L E++ Sbjct: 1452 FKEVSIDDTSMIKVEAMDKTVTAMLTVIEGDLYFTTKLQNYTAVEKDEVKLRCELSKAIG 1511 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 DV W +DG+ + P KN G R L +R + GEY+C + TA++ + E Sbjct: 1512 DVKWFKDGKELTPSKN-IAIITDGKKRILTVRKAEKANIGEYTCDCGSDKTTAKLNIEER 1570 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 +I+ L + +V + A FE E+++ D W G +Q S +++ +G + L + Sbjct: 1571 DIKIVRPLYSVEVTETETAKFETEISEDDVHGNWKLKGEALQQSADVEMKEEGTRHMLVL 1630 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 Y+ +D AG N++ +A L V+ S+ L + ++V A A E+ E + Sbjct: 1631 YNVHMDMAGAVDFSAANARSSAQLRVKARSVGLVRPLKD-VMVTAGETATFECELSYEGI 1689 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVV 1284 V W+ +E E+ + L IR + E V L AK T+ + V Sbjct: 1690 VVEWFLGGQKMEAGERVKTRVAGRAHALTIRDVNLSEAGE---VKLTAKDFQTQAHLIVK 1746 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKS 1342 E P + + ++ S VTL A + N E W + + ++K K Sbjct: 1747 EPPVEFTKPLEDQTVEEDSTVTLEC---AVSRENAEVRWFRDGQELRKTKKFDLLSLGCK 1803 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSPPGKPNILEIDSSSINICW 1401 L I + D +Y C D + + + + P + +++ Sbjct: 1804 RMLVIHNCSSEDIKMY------TCDTKDFKTSCYLDVTPPHVEFTKLLQDVEVREREAAK 1857 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 E E + S + + + EI K T + +Q F A E D Sbjct: 1858 FECEVSRESAKVRWFKDGSEIR-----KGKKYEITASGVQRTLIIHKSGFDDEAEYECD- 1911 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + S+T+ VI+E +P K L N+ + +++ C +VTWYR ++ Sbjct: 1912 ARTSKTSGLLTVIEE----APKFTKNLSNVEGMETDSVKMICEVSKA-SAEVTWYRGEEE 1966 Query: 1522 LKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 L YE + Y C ++TS V+ + + IS Sbjct: 1967 LPEV-GRYEQIMDGRKRILIIKGLRMEDAGQYTC---RLSPNIKTSAVLQLNELAAEFIS 2022 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 Q+ G T + EV W++ +LEN ++ I ++ K V+ +K + Sbjct: 2023 RPQ-NQEVVEGQAAEFTCSVSK-ETYEVKWFRGDKELENGDKFVIVSEGKRRVLTVKNCE 2080 Query: 1637 RSHSSKY-----TIEAS-NTAGTSSVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKP 1689 Y I+AS + T + V + D K ++ E + E +W Sbjct: 2081 LKDEGGYVAHIGAIKASADLLVTEKLRVITPIKDTEVKEGSEIVFNCEANAEGAKAKWLK 2140 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDR-DVETYCIQKLNENCE 1736 ++ E +KY + + DN +++ D + D +Y + N+ E Sbjct: 2141 N-EETIFETSKYMMAQR--DNVFSLRIRDAQKTDEASYTVSLTNQRGE 2185 Score = 131 bits (317), Expect = 2e-28 Identities = 241/1104 (21%), Positives = 421/1104 (38%), Gaps = 84/1104 (7%) Query: 1004 QETSTMLVVKETIPEF----IRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKP 1058 + T +LV E +P +R + +VK ILE E+ + V W+R +K Sbjct: 8038 EPTDPVLVCAENVPPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPRVTWKRGDNSLKS 8097 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEIITRLQN 1115 + + +R H + T H G Y+ + + + + +V + I+ Sbjct: 8098 CEGQVITHQRHHFQLEMTAVTKEHT-GVYTILAENATPPGPIVNPSVTDTTYSTISLAWT 8156 Query: 1116 QKVNKGNKAT--FEIELTKGDALVRWFKDG--SEIQFSNH-IQLTIDGKKQKLKIYDCDL 1170 N G + +E + + W + +Q +++ IQ ID + + +I + Sbjct: 8157 APANDGGSPVIGYLVECKRANT-ADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNR 8215 Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTW 1229 E G I+ E ++ L+ E + + A L I +TW Sbjct: 8216 VGFSEPVEVPGKHVAKDIIVAPEAVLSAELK--EGLELNAGATMRLEATIKGRPRPKITW 8273 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP 1287 K + I+D + + S +++ D +Y L L + V+V + P Sbjct: 8274 AKMNTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYIFNLESLAGMKMYTIVVKVYDTP 8333 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP--SIDSKSASL 1345 V+ + K G+ + + P + + V I++K + SI S + + Sbjct: 8334 GPPVNLMVKETSKDGASI-----FWDSPLTDGGYEVTHYIVEKRDTERKAWSIVSMNCNK 8388 Query: 1346 TIKKVENTDAG-IYKLRLE--NNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 T +V + +AG Y R+ N G + + +V ++P + + S I Sbjct: 8389 TSFEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMDFKTVLVTKDSCTI 8448 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 W +P + G S II YV+E D ++ + Q S ++L Y +R A+N+ Sbjct: 8449 SWKKPLSDGGSRIISYVLEVLNGD-DKYKELMRSKNMQYSAKDLVEGKEYTYRVKAINDS 8507 Query: 1460 DISDASETTEYYKVIKETKIQSPTVE-KPLKNI--TTEPNEDIELTCIFGGVPQPKVTWY 1516 A E T V+ + +I P + + L N+ + + L G P PKV+W Sbjct: 8508 GEGAAKELT----VVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWK 8563 Query: 1517 R-DGKKLK-TAKATYENRXXXXXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 + D + LK + + E+ Y N G E++ + + KP Sbjct: 8564 KGDDEDLKDSGRVCAESSSVNTTLLIRDCQRNDASKYTITLRNSAGIKESTIFIRVVGKP 8623 Query: 1572 VITISNEDIKQKHKVGD----EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 I + IK K D +W G I K + + +++ +T Sbjct: 8624 GIPVG--PIKFKDVTADGATLKWGAPKDDGGSDIANYILEKRDS--VTNMWVTVSSSVET 8679 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRES 1682 + +R+ L + + A N G S + ++ P P P IM + S Sbjct: 8680 NSMRVTGLHEGTEYIFRVCAENKYGVGEGLKSDPIIAKHPFNVPEAPPPPQIM-NMQHNS 8738 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 + W P GG +T Y +E E ++ W + + ++ + L E EY FRV+ Sbjct: 8739 AYLAWLDPRKTGGSPITGYHLEFKERNSMLWKRASPTPLRMKEQSVTGLTEGLEYEFRVM 8798 Query: 1743 AQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 A N G + + ++P V +DVP I +V + W + +GG + Sbjct: 8799 AINLAGIGKPSAPTDPRVALDPIDVPG----KPEVISITKSTVTLQWIEPQFDGGHRLTG 8854 Query: 1802 YKVEIKQ-EGKKW-KXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSD-DKI 1857 Y +E + K W K A + L Y+FRI A+N G P + D I Sbjct: 8855 YIIEKRDLPSKIWMKANNVNVLEPAFTVMDLQEGCKYEFRIRAKNAAGAISPASEQTDTI 8914 Query: 1858 TIGKTLTPPSQPRNFVVSES-TSRS-VTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTK 1914 P+ + V E T R+ T+ T G +P + + K K + Sbjct: 8915 ICRDEYAAPTIVIDAQVKEGLTVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQ 8974 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 I T S I+ KD + I+A N GV T +V VP P P+E Sbjct: 8975 IETTPTS-STLSIKYATRKDTGEYVITASNPFGVKEETVKVTV-----LDVPDSP-GPIE 9027 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW--MEVGKVDVNTLKFNIRDLS 2032 + S V SW P +GG+P+ Y + R+ ++ +W +E VD + + + L Sbjct: 9028 CSGISSEKVALSWTAPTENGGSPIKYYTLEKRETSRLLWTVLEEKVVDCHYVAYK---LI 9084 Query: 2033 ENHTYMIRIYARNEIGLSEPLESD 2056 + + Y R+ A N+ G SEP S+ Sbjct: 9085 QGNEYFFRVSAVNQYGASEPSHSE 9108 Score = 131 bits (316), Expect = 2e-28 Identities = 93/291 (31%), Positives = 133/291 (45%), Gaps = 14/291 (4%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR----IQKLSINTT 1834 I +S Y+TW E NGGS I +Y +E + KK + KL++N Sbjct: 4909 IKADSCYLTWDVPEDNGGSEITNYIIERRDASKKKSDFEVQTTNLIDRRYGVYKLNVNGA 4968 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 YQFRI A N+ G S S+ K+ + P PRN + +T+ ++TL W P NGG Sbjct: 4969 YQFRIKAENKYGISDGCDSE-KVQLSDPFGLPGPPRNPKIIAATATTMTLTWDPPLDNGG 5027 Query: 1895 SPITNYIIEFKTVKGKSWTKI----VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS 1949 S I Y +E + W ++ VT ++ + + E E FRI+A N GV Sbjct: 5028 STIQGYWLEKRERGAVYWGRVNRAPVTKPAVKGLQYTVLKLIEGTEYQFRIAACNAAGVG 5087 Query: 1950 LPTESQSVRLEKH-ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 P+E+ R PS P AP E++ N + SW P+ DGG+P+ GY I + + Sbjct: 5088 PPSEASECRFAVDPCNPPSSPGAP-EVKDKTKNSITLSWSPPDKDGGSPVKGYIIEVHEE 5146 Query: 2009 TKTMWMEVGKVDV--NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 W V D + + + DL E RIYA N G SEP + E Sbjct: 5147 GCPDWRRVNPADKLHPSTELFVSDLKEGKKCRFRIYAVNAAGNSEPARTAE 5197 Score = 125 bits (302), Expect = 1e-26 Identities = 174/872 (19%), Positives = 337/872 (38%), Gaps = 63/872 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+K E + + C V+ ++ W ++GEE +P+ E M Sbjct: 1928 PKFTKNLSNVEGMETDSVKMICE-VSKASAEVTW-YRGEEELPEVG---RYEQIMDGRKR 1982 Query: 694 VLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +L I ++ G YT ++ N + A L + E + P +V +G++ Sbjct: 1983 ILIIKGLRMEDAGQYTCRLSPNIKTSAVLQL------NELAAEFISRPQNQEVV-EGQAA 2035 Query: 753 ILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + V + W + +K ++ S+G +T+ K ++KDEG Y Sbjct: 2036 EFTCSV-SKETYEVKWFRGDKELENGDKFVIVSEGKRRVLTV-KNCELKDEGGYVAHI-- 2091 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G + SA + V E I ++ VKE I + W +N Sbjct: 2092 --GAIKASADLLVTEKLR-------VITPIKDTEVKEGSEIVFNCEANAEGAKA-KWLKN 2141 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH-GARVTIDVEKV 928 E I + L I + + D Y +N G+ + A + EK Sbjct: 2142 EETIFETSKYMMAQRDNVFSLRIRDAQ-KTDEASYTVSLTNQRGEQATCTASAKVAEEKH 2200 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F++ ++ ET+E KT+ C+ + V KW +E++ +G Sbjct: 2201 RFLQPIE-DIETQEKKTISFVCKVNRPEVMVKWTKAGQEVALSKRIVYRADGLKHTLTIK 2259 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G +V + + L+V E +F L+D V E + A ++N E A V Sbjct: 2260 DCVMEDEGEYTAVVGEDRCTADLMVSEAPADFTALLKDQTVTEFEDADFTCKLNKEKASV 2319 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W ++G I+ + +Y ++ G + +L I+ DE EY+C + + A + V E P Sbjct: 2320 KWYKNGREIR-EGPRYHMQREGKVCRLIIKECRPDDECEYACGMDERRTRARLFVEETPV 2378 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 EII Q+ + FE+EL K V+W ++ I + Q+ +GK +L++ + Sbjct: 2379 EIIRPPQDMLEPPASDIVFEVELNKDRVEVKWMRNNMIIVQGDKYQMISEGKIHRLQVCE 2438 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPD-ETL 1225 D GEY + A L + P I T + ++ A + V Sbjct: 2439 IRPRDQGEYRIVAKDKDARAKLELAAVPKIKTT---DQKLVTDAGKPFIMRVPYDAYPRA 2495 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283 + W+ + + + T + + R ++ +++DQ +Y V+ + + + ++V Sbjct: 2496 EAEWFFEDTSLPVQNIDTSVDKTEYR---LKSPSKEDQGQYKVVISNKHGAAEAFIVLDV 2552 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND-----EWIVNSKIIKKCKHTKPSI 1338 ++ P + + R+ +D + + ++ P+ + ++V + +K+ + Sbjct: 2553 IDVPGSV----KNLRVLDTADGEVSLAWEE-PESDGGSKIIAYVVERRDVKRKTWALATD 2607 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA------DVEMNVTILDKPSPPGKPNILEI 1392 + + + + A ++++ N G D D P P + + Sbjct: 2608 RADTPEYCVTGLHKDSAYLFRVCARNRVGSGPAVVTEDAVQAKNKFDVPDAPEDVAVETV 2667 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYR 1450 + I W P+ G S I YV+E ++ + +W + + S + ++ N Y Sbjct: 2668 NKFGATISWKPPKFDGGSEITAYVIELRDRTSVKWEATLECSPHDLSATLNDVVENKEYI 2727 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 FR A N + S T K++ + SP Sbjct: 2728 FRVRAENRAGVGRPSPATNPVKIMDPIERPSP 2759 Score = 125 bits (302), Expect = 1e-26 Identities = 183/893 (20%), Positives = 352/893 (39%), Gaps = 74/893 (8%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVK 1249 ++E + T+ +PE + A + + + + W + + + + + + Sbjct: 7655 IKEQMLEPTILMPESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGN 7714 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 LII+ + D EY+ V ++ S T LK+ + + P E I Sbjct: 7715 LCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPP---EGPVEISDIDSDAC 7771 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKS-ASLTIKKVENTDAGIYKLRL 1362 + + P + + + +++KC ++ ++ S S S + K+ ++++R Sbjct: 7772 SLSWNK-PLEDGGSNITNYVVEKCDVSRGDWVTAVSSVSKTSCRLGKLIPGKEYVFRIRA 7830 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPN---ILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 EN G +D + ++ K P G+P I + + + + WD+P G S I Y +E Sbjct: 7831 ENRFGLSDPIQSDRMVAK-FPFGEPLNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIER 7889 Query: 1420 QEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E ++ ++ + + TQ L Y F+ A+N S S T Y V T Sbjct: 7890 KERNSLFFVKANDTIVRTTQYPCAGLIKGLEYTFKVSAINRACQSKPSANT--YFVTART 7947 Query: 1478 KIQSPTVEKPL---KN----ITTEPNEDIELTCIFGGVPQPKV---TWYRDGKKLKTAKA 1527 + +P + L KN + T P D I V +V +W R + Sbjct: 7948 PVYTPGKPEVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPK 8007 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHK 1585 + + E +V + P N +++ K K Sbjct: 8008 EEYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKGLKVK 8067 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G ++ A + G P P V W + N L++ + IT + + + + + H+ YTI Sbjct: 8068 AGATVILEAEVFGKPMPRVTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKEHTGVYTI 8127 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYA 1702 A N + P GP++ + + + ++++ W P +DGG + Y Sbjct: 8128 LAEN-----------------ATPPGPIVNPSVTDTTYSTISLAWTAPANDGGSPVIGYL 8170 Query: 1703 IEKHEPDNNRWIKVADVDRDVE--TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIV 1759 +E + WI+ ++ R+++ +Y IQ L + EY R+ A N VGFSE +E V Sbjct: 8171 VECKRANTADWIR-CNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVGFSEPVEVPGKHV 8229 Query: 1760 IKTALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818 K + P ++ N + + K P I + ++ K + Sbjct: 8230 AKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRPKITW-AKMNTNIKDRQGIVI 8288 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 I + Y Y N SL I + K P P N +V E++ Sbjct: 8289 KSSNTDTIVMVENVNRYDAGKYIFNL--ESLAGMKMYTIVV-KVYDTPGPPVNLMVKETS 8345 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 ++ W P ++GG +T+YI+E + + K+W+ IV++ + + ++ F Sbjct: 8346 KDGASIFWDSPLTDGGYEVTHYIVEKRDTERKAWS-IVSMNCNKTSFEVPDLNAGRSYCF 8404 Query: 1939 RISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR--MVGSNIVMTSWGTPEWDGG 1995 R+S N +G E + SVR + P A ++ + +V + SW P DGG Sbjct: 8405 RVSGVNKLGAGEYCETADSVRASEE------PGAVMDFKTVLVTKDSCTISWKKPLSDGG 8458 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + ++ Y + + + + E+ + ++++ +DL E Y R+ A N+ G Sbjct: 8459 SRIISYVLEVLN-GDDKYKEL--MRSKNMQYSAKDLVEGKEYTYRVKAINDSG 8508 Score = 121 bits (292), Expect = 2e-25 Identities = 65/198 (32%), Positives = 107/198 (54%), Gaps = 7/198 (3%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT--KIVTVGGSV 1922 PP P N + E T + ++W P+ +GG+PITNY++E K VK K W +V+ G+ Sbjct: 6607 PPVGPINIL--EVTPDYMMIQWRAPKDDGGTPITNYVVEKKDVK-KPWEPWSVVSSSGTN 6663 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 + + +++ E + R+ AEN +G+S ES + P PP P+ + N Sbjct: 6664 TKAKVSRLEKGREYVVRVRAENKIGISTGLESPPTIAKHMFNPPGPPGLPV-CSDITENA 6722 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 V W P++DGG+P+ GY I R++T W+ V K V L++ + L E ++Y R++ Sbjct: 6723 VTVEWTLPDYDGGSPISGYVIERREMTGK-WIRVNKTPVLDLRYRVSGLFEGNSYEFRVF 6781 Query: 2043 ARNEIGLSEPLESDEPFK 2060 A N G+S+P + +P K Sbjct: 6782 AENIAGISDPSLASDPVK 6799 Score = 119 bits (287), Expect = 8e-25 Identities = 94/325 (28%), Positives = 133/325 (40%), Gaps = 11/325 (3%) Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 + A NP G E E + + T LDVP I +E V ++W +NGGSPI Sbjct: 8999 ITASNPFGVKE----ETVKV-TVLDVPDSPGPIECSG-ISSEKVALSWTAPTENGGSPIK 9052 Query: 1801 DYKVEIKQEGKK-WKXXXXXXXXXARIQ-KLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 Y +E ++ + W + KL Y FR+ A N+ G S P S+ + Sbjct: 9053 YYTLEKRETSRLLWTVLEEKVVDCHYVAYKLIQGNEYFFRVSAVNQYGASEPSHSE-AVK 9111 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 + PP P V + S T+ W P +GGS I Y +E K KG W + Sbjct: 9112 MVDRFGPPGPPSKPEVEKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRWVRASKK 9171 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRM 1977 + + + E E FR+ AEN G P+E S VR A P PP P I Sbjct: 9172 SIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVNP-RITD 9230 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 +WG P +GG + GY I + W++ +F + +L Y Sbjct: 9231 TTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSPHRITEFVVAELETGAKY 9290 Query: 2038 MIRIYARNEIGLSEPLESDEPFKVI 2062 RI A N G EP E+ E ++I Sbjct: 9291 HFRISAVNSKGAGEPAETSELVEII 9315 Score = 118 bits (284), Expect = 2e-24 Identities = 117/476 (24%), Positives = 192/476 (40%), Gaps = 33/476 (6%) Query: 1600 PPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 PPP+ ++ LE +KE +N T K + + LK S K+ + A N G S Sbjct: 7589 PPPQPPVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTE 7648 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN-RWIKVA 1717 T + + + P I+ ESV+ G +L A+ +P +W++ Sbjct: 7649 TREPVEIKEQMLEPTILMP---ESVSAR-------AGAKLRVEAVVAGKPAPMCKWMRGE 7698 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTAL-----DVPSXXX 1771 D + + C + + +++ G +S E+ + AL D+P Sbjct: 7699 DAVVPSSRLAVHQSGNLCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPPE 7758 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKL 1829 ID+++ ++W ++GGS I +Y VE + W + R+ KL Sbjct: 7759 GPVEISDIDSDACSLSWNKPLEDGGSNITNYVVEKCDVSRGDWVTAVSSVSKTSCRLGKL 7818 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 Y FRI A N G S P SD + P +P N +S++ + + W +P Sbjct: 7819 IPGKEYVFRIRAENRFGLSDPIQSDRMVA----KFPFGEPLNCCISKTNKDCMFVAWDKP 7874 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 +GGSPIT Y IE K + K T+ + C IK E F++SA N Sbjct: 7875 SGDGGSPITGYYIERKERNSLFFVKANDTIVRTTQYPCAGLIKGL-EYTFKVSAINRACQ 7933 Query: 1949 SLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 S P+ + V P P E+ + N V W P+ DGG+ ++GY + Sbjct: 7934 SKPSANTYFVTARTPVYTPGKP----EVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMR 7989 Query: 2008 VTKTMWMEVGKVDVNTLK--FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 V W+ N K + + L + Y R+ A+ + +S+P E +P V Sbjct: 7990 VPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLV 8045 Score = 118 bits (283), Expect = 2e-24 Identities = 93/321 (28%), Positives = 143/321 (44%), Gaps = 27/321 (8%) Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812 LES + TA +P N S ++W E +GGSPI Y +E ++ KK Sbjct: 3973 LESTLLFCTTATGLPGQCKDIRSTDITKN-SCQVSWEMPEDDGGSPISSYTLERREASKK 4031 Query: 1813 --WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL------PYTSDD------KIT 1858 ++ L +N Y FR+ A N++G P +++ + Sbjct: 4032 TYMPVLSGENVLTHTVKDLYVNCEYFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLI 4091 Query: 1859 IGKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 + LT P P + TS+S+T+ W P+++GG PI YI+E G + ++ Sbjct: 4092 LNFDLTEKPDPPLQVETCDPTSKSITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTP 4151 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 + +KE E FR+ AEN GVS P S+S +L K A P AP+ Sbjct: 4152 SLVPGFSFVVTGLKENMEYQFRVRAENVAGVSEP--SRSTQLLKAADPVDKPGAPINFTF 4209 Query: 1978 --VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV-NTLK---FNIRDL 2031 + + V+ +W PE DGG+ +L Y + RD K EVG + + +TLK F + L Sbjct: 4210 DEIRNTSVICNWEPPEDDGGSEILNYILEKRDYKKE---EVGWITITSTLKGNSFPVTKL 4266 Query: 2032 SENHTYMIRIYARNEIGLSEP 2052 E Y+ R+ A N+ G P Sbjct: 4267 IEGKEYIFRVTAENKFGCGPP 4287 Score = 116 bits (279), Expect = 7e-24 Identities = 159/713 (22%), Positives = 269/713 (37%), Gaps = 65/713 (9%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE------------- 1426 KP P K +LEI +S + W +P G + I YV+EY E+ E Sbjct: 7538 KPDPCEKIEVLEITKNSATVGWIKPARDGGAKIDGYVIEYIEVHEGEEPPPPPPQPPVVE 7597 Query: 1427 -----------WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 W + + + S+ LK + Y+FR A N + +S +ET E + IK Sbjct: 7598 DEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTETREPVE-IK 7656 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--DGKKLKTAKATYE--N 1531 E ++ PT+ P ++++ + + + G P P W R D + A ++ N Sbjct: 7657 EQMLE-PTILMP-ESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVHQSGN 7714 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ---KPVITISNEDIKQKHKVGD 1588 Y +A N +V + + I+ P + DI Sbjct: 7715 LCVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRDIPGPPEGPVEISDI-DSDACSL 7773 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 W G + + + D +++ KTS R+ +L + I A Sbjct: 7774 SWNKPLEDGGSNITNYV-VEKCDVSRGDWVTAVSSVSKTS-CRLGKLIPGKEYVFRIRAE 7831 Query: 1649 NTAGTSS-VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 N G S ++ V P + + +++ + + W P DGG +T Y IE+ E Sbjct: 7832 NRFGLSDPIQSDRMVAKFPFGEPLNCCISKTNKDCMFVAWDKPSGDGGSPITGYYIERKE 7891 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 ++ ++K D Y L + EY F+V A N ++ S TA P Sbjct: 7892 RNSLFFVKANDTIVRTTQYPCAGLIKGLEYTFKVSAINRA--CQSKPSANTYFVTA-RTP 7948 Query: 1768 SXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXXXAR- 1825 I SV + W + +GGS II Y VE ++ G W + Sbjct: 7949 VYTPGKPEVLDITKNSVTLVWTRPKNDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKE 8008 Query: 1826 ---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + L + YQFR+ A+ + S P D + + PP N + + Sbjct: 8009 EYTVTGLERDLHYQFRVIAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKG----- 8063 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 LK G + I + K + +W + G + + C + F++ Sbjct: 8064 -LK----VKAGATVILEAEVFGKPMPRVTWKR----GDNSLKSCEGQVITHQRHHFQL-- 8112 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 E T T ++ L ++AT P P P S I + +W P DGG+P++GY Sbjct: 8113 EMTAVTKEHTGVYTI-LAENATPPGPIVNPSVTDTTYSTISL-AWTAPANDGGSPVIGYL 8170 Query: 2003 IAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + + W+ ++ + I++L + + Y RI A N +G SEP+E Sbjct: 8171 VECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCRITAVNRVGFSEPVE 8223 Score = 115 bits (277), Expect = 1e-23 Identities = 77/302 (25%), Positives = 129/302 (42%), Gaps = 13/302 (4%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXX-ARIQKLSINTTY 1835 I + ++ W E NGG I +Y +E K E K+ W ++ +L Y Sbjct: 7103 ISIDRCHLAWEAPEDNGGCDIYNYIIE-KCETKRGVWSVHSNAVITNKTKVTRLIEGNEY 7161 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 FR+ A N++G P + I G + P P V++ +T++W+EPE +GG Sbjct: 7162 IFRVRAENKMGPG-PAVQSEPIVAGTQFSVPYAPEMPEVTKIAKEEMTVQWSEPEKDGGK 7220 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 PIT Y++E + W+ + + + + +R+ A N +G+S P++S Sbjct: 7221 PITGYLLEKREEHAVRWSPVNKDPTPATHFTVTGLIPLHDYQYRVKAVNEIGISSPSKSS 7280 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--- 2012 K A P P + L + + V W P GGAP++GY + +R Sbjct: 7281 RAVTAKDAVGPPAPPSNLRVLDSTKSTVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGD 7340 Query: 2013 --WMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHA 2069 W + F + L + Y R+ A+N++G+S P + + VIP E A Sbjct: 7341 DGWKRCNVAAQLVVCDFTVTSLDDQLVYEFRVSAQNQVGMSLPCDLKD--AVIPKEILEA 7398 Query: 2070 DE 2071 E Sbjct: 7399 PE 7400 Score = 113 bits (272), Expect = 5e-23 Identities = 134/608 (22%), Positives = 246/608 (40%), Gaps = 47/608 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKF--TLISDVKK 1250 P ++ + E ++V A + + + T D+TW + S + K T IS Sbjct: 5743 PEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRDGSALPPEAKVETTFISSA-- 5800 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFP-PKIVDYEREYRIKRGSDVTL 1307 LII+ C+ YT +A K + VEV++ P P + + E + Sbjct: 5801 --LIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEVLDVPGPVGIPFTTENLSNDSCKLNW 5858 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 P +IV + ++ T S + + + + + +++ EN G Sbjct: 5859 FFPENDGGSPISNYIVEKREAERKAWTSVSFTASRTNAVAHGLTSGKSYFFRVAAENAIG 5918 Query: 1368 ---HADVEMNVTILDKPSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQE 1421 + V I + S P +P LE+ + I++ W P++ G S I Y++E + Sbjct: 5919 IGPFVETAAEVVIREPISIPERPEELEVHKVTKDLISVTWKPPKSDGGSEITMYILEARM 5978 Query: 1422 I--DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 I D ++ + + + + + L+ +Y FR AVNEV S T+ + + ++ Sbjct: 5979 IGKDKFTRLTKEKLLERKYTYDGLREGDTYEFRVIAVNEVGPGKPSFCTK--PITCKDEL 6036 Query: 1480 QSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXX 1537 + PT+E ++ I E L + G P P + WYRD +++K K ++N Sbjct: 6037 EPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTLTTMS 6096 Query: 1538 ---XXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y + N G + C VVG+ + P + +++ + L Sbjct: 6097 LGLMKAQREHSGRYVVVVENSTGSRKGICNVTVVGVPEAPEM----PTVREVYATNALVL 6152 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEAS 1648 +G P + Y K K ++ T+E + R+++L ++ + A Sbjct: 6153 WNRPRDGGKP--ITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAE 6210 Query: 1649 NTAGTSS-VEVTLKVYDK-----PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 N GT E + + K PS P P + +++SV+++WK P DG + Y Sbjct: 6211 NELGTGDPSEPSKPILAKDPIVCPSPPVTPEAY-DKTKDSVSLKWKLPRHDGKGRIFGYL 6269 Query: 1703 IEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759 +E +P WI+ + + + LN+ EY+FR+ N G S+ A EPI Sbjct: 6270 VEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIK 6329 Query: 1760 IKTALDVP 1767 + L+ P Sbjct: 6330 VHDRLEKP 6337 Score = 112 bits (269), Expect = 1e-22 Identities = 65/239 (27%), Positives = 112/239 (46%), Gaps = 9/239 (3%) Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 R++ S Q+++ N+ G + + D I + P +N V ++ V+L Sbjct: 2521 RLKSPSKEDQGQYKVVISNKHGAAEAFIVLDVIDV------PGSVKNLRVLDTADGEVSL 2574 Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 W EPES+GGS I Y++E + VK K+W + T E+C+ + + +FR+ A N Sbjct: 2575 AWEEPESDGGSKIIAYVVERRDVKRKTWA-LATDRADTPEYCVTGLHKDSAYLFRVCARN 2633 Query: 1945 TVGVSLPTESQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 VG ++ +V+ + VP P + + V SW P++DGG+ + Y I Sbjct: 2634 RVGSGPAVVTEDAVQAKNKFDVPDAPE-DVAVETVNKFGATISWKPPKFDGGSEITAYVI 2692 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 +RD T W + + L + D+ EN Y+ R+ A N G+ P + P K++ Sbjct: 2693 ELRDRTSVKWEATLECSPHDLSATLNDVVENKEYIFRVRAENRAGVGRPSPATNPVKIM 2751 Score = 109 bits (262), Expect = 8e-22 Identities = 63/202 (31%), Positives = 97/202 (48%), Gaps = 8/202 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P PR+ VS+ T + L W P+ +GG + +Y IE KTV GK+WTK V + Sbjct: 5338 PGPPRDLKVSDVTRGTCRLTWKPPQCDGGERVKSYFIEKKTVHGKAWTK-VNPACAAQSL 5396 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 + ++ E +FRI AEN G T++ + + P PPT L+I+ V V Sbjct: 5397 VVPDLNNGQEYLFRIRAENRFGFGPFTQTIERTKASDPINPPDPPTR-LKIQNVHKGAVT 5455 Query: 1985 TSWGTPEWDGGAPLLGYNIAI-----RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 +W P+ DGG+P+ Y++ + K W + DV + +F + DL+ Y Sbjct: 5456 LTWKAPKNDGGSPVTHYSVDLLCWDASGTQKEHWRRCNRRDVESTRFKVEDLTYGDEYEF 5515 Query: 2040 RIYARNEIGLSEPLESDEPFKV 2061 R+ A NE G S P + P + Sbjct: 5516 RVVAYNEAGPSRPSTTAGPITI 5537 Score = 102 bits (245), Expect = 9e-20 Identities = 105/427 (24%), Positives = 182/427 (42%), Gaps = 38/427 (8%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 G+ A FE +++ A+ W KDG ++ + T DGK +KL I D L D GEY+C Sbjct: 552 GSSAVFECQISPSTAITSWMKDGGNLREGPKYKFTADGKDRKLNILDVQLSDTGEYTCVA 611 Query: 1181 GNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 N+ CTA L VEE + + L YLT E+ E DVTW + +V+ Sbjct: 612 RNAGKEITCTAKLIVEELPVKWVKELEPETTCMKGQPMYLTCELNKER-DVTWKRNGAVL 670 Query: 1237 EDTEKFTLISDV-KKRTLIIRKCTEDDQCEYTCVL---LDAKSTTKLKV-EVVEFPPKIV 1291 + I+ + + + I+ TE+D YTC + D +TT +KV E+++ +V Sbjct: 671 KKKAGKVAINIIGLQHAVTIQNATEEDTGAYTCEVEGREDISTTTNVKVLEIIK--DWLV 728 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 R+ +K S T + PN +W+ I + + + D + +LTI + Sbjct: 729 KPLRDQHVKPKSKATFKGELFK-DTPNWKWLKGETEITPSEKMEIAKDGANVTLTINNCQ 787 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D Y + +E+ A + + + + + IL+ +S+ + E N Sbjct: 788 PDDVSEYTIEVEDRRYTAKLTLGGAV-RRRFQEREAEILK-PLASLEVVEKEEAN----- 840 Query: 1412 IIYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + E E D EW ++ T++ ++K RF + V + A E + Sbjct: 841 ---FDTEISEEDIIGEW-KLRGQVLTRSPTCDIKLEGRKRF--LTLKNVQVDQAGEVS-- 892 Query: 1471 YKVIKETKIQSPTVEK-------PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 Y+ + TV++ PLK+++ + + C PKV W++ G ++ Sbjct: 893 YQALNAVTTGMLTVKELEMGFVDPLKDVSVPEKKQAKFECTV-TKEVPKVMWFK-GAEIV 950 Query: 1524 TAKATYE 1530 T YE Sbjct: 951 TPGPKYE 957 Score = 99.1 bits (236), Expect = 1e-18 Identities = 60/193 (31%), Positives = 87/193 (45%), Gaps = 2/193 (1%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 L P ++ VS + L W PE NGG I NYIIE K W+ + + Sbjct: 7089 LDRPGPVQDLKVSGISIDRCHLAWEAPEDNGGCDIYNYIIEKCETKRGVWS-VHSNAVIT 7147 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 ++ + + E +E IFR+ AEN +G +S+ + +VP P P E+ + Sbjct: 7148 NKTKVTRLIEGNEYIFRVRAENKMGPGPAVQSEPIVAGTQFSVPYAPEMP-EVTKIAKEE 7206 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 + W PE DGG P+ GY + R+ W V K F + L H Y R+ Sbjct: 7207 MTVQWSEPEKDGGKPITGYLLEKREEHAVRWSPVNKDPTPATHFTVTGLIPLHDYQYRVK 7266 Query: 2043 ARNEIGLSEPLES 2055 A NEIG+S P +S Sbjct: 7267 AVNEIGISSPSKS 7279 Score = 86.6 bits (205), Expect = 7e-15 Identities = 49/168 (29%), Positives = 73/168 (43%), Gaps = 1/168 (0%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + G+ + L D + P P +W +++ + L+I D Y Sbjct: 3168 RAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDHSKLSIANTTRGDTATYI 3227 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + N CG A ++V ILDKP PP +I EI S S + W+ P + G S I Y+VE Sbjct: 3228 IEAVNVCGRATATIDVNILDKPGPPAAFDISEITSESCCLAWNPPRDDGGSPITNYIVES 3287 Query: 1420 QEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 ++ D EWI + K T L Y FR A N+ I + +E Sbjct: 3288 RQTDKEEWIKLSATVKHTTFKACKLTGMKEYIFRISAENQFGIGEPAE 3335 Score = 86.2 bits (204), Expect = 9e-15 Identities = 56/208 (26%), Positives = 95/208 (45%), Gaps = 14/208 (6%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P Q ++ ++ T S + W PE +GGSPI++Y +E + K++ +++ G +V H Sbjct: 3987 PGQCKDIRSTDITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLS-GENVLTH 4045 Query: 1926 CIENIKEKDEIIFRISAENTVGVSL------PTESQSVRLEKHATV-----PSPPTAPLE 1974 ++++ E FR+ A N VG P ++ V+L + + P PL+ Sbjct: 4046 TVKDLYVNCEYFFRVKAVNKVGAGQYLELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQ 4105 Query: 1975 IRMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 + S + +W P+ DGG P+ GY + + + V V F + L Sbjct: 4106 VETCDPTSKSITITWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLK 4165 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFK 2060 EN Y R+ A N G+SEP S + K Sbjct: 4166 ENMEYQFRVRAENVAGVSEPSRSTQLLK 4193 Score = 79.8 bits (188), Expect = 8e-13 Identities = 51/172 (29%), Positives = 78/172 (45%), Gaps = 4/172 (2%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 K G+ + L P P +W+ + K I S L+I + + D G Y Sbjct: 6524 KAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTILSISECQRGDTGEYV 6583 Query: 1360 LRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 L + N G V ++VT+LD P PP G NILE+ + I W P++ G + I YVVE Sbjct: 6584 LIVTNPAGSKTVALHVTVLDLPGPPVGPINILEVTPDYMMIQWRAPKDDGGTPITNYVVE 6643 Query: 1419 YQEIDT--TEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 +++ W V + T T+ + L+ Y R A N++ IS E+ Sbjct: 6644 KKDVKKPWEPWSVVSSSGTNTKAKVSRLEKGREYVVRVRAENKIGISTGLES 6695 Score = 78.6 bits (185), Expect = 2e-12 Identities = 88/413 (21%), Positives = 169/413 (40%), Gaps = 39/413 (9%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-PTKSDGDTHSITI 791 + P+ PL+ + V +GE + L V+G+P + W K+ + +K+ T+ S+ + Sbjct: 4 QAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCL 63 Query: 792 LKPKKVKDE-GVYTLKAENSEGIAETSAVITVEE------PTE----------ENAEPPL 834 K E G Y KA N+ G + ++V+E P E + Sbjct: 64 EVEAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRRLDNLF 123 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVIT 893 FI + I+ EKGT +A++ P+P++ W + I+P I+ + G++ ++ I Sbjct: 124 FIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDAKMEIR 183 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---------KVTFVKHLQKSYETEEGK 944 V ++ DSG Y+CVASN G+ A + + + +V K K ++ + Sbjct: 184 EV-TKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGEFGDVRVMLKKTPSKQKSPKKEE 242 Query: 945 TVILECQTSHTVSTKWYHN-KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 I+E H K Y +E D+R I+Q V + + ++ Sbjct: 243 WNIVELLRGH--DPKEYEKILQEHDIHDYRAILQAMDLLKKEKEAEPSKTVDQVDRVEEE 300 Query: 1004 QETSTMLVVKETIP----EFIRKLQDFEVKEKDVAIL--EVEINSETADVVWERDGEIIK 1057 + ++ I + + D + E A ++IN + W + ++ Sbjct: 301 DMARFIQQLESHIAAEPVSVLEDITDQKTAENQSATFRCRIQINYPEISLTWYKGTRRLE 360 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII 1110 + +KY+ G + L + + DEG+Y + TA + V P+++ Sbjct: 361 -QGHKYEISSVGDLHCLKVNDCDPSDEGDYRVVCGPHISTAMLAVAGKCPDLL 412 Score = 76.2 bits (179), Expect = 9e-12 Identities = 62/268 (23%), Positives = 116/268 (43%), Gaps = 13/268 (4%) Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 P+++ + +++ E + W + L + Y+FR+ A+N +G SL + + + Sbjct: 7594 PVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTETREPV 7653 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWTKI 1915 I + + P+ ++ ES S K G +P+ ++ V S Sbjct: 7654 EIKEQMLEPT----ILMPESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPSS-RLA 7708 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 V G++ I+++ D + + AEN+ S T++ + + +P PP P+EI Sbjct: 7709 VHQSGNLCVLIIKDVSRTDSGEYSLVAENSS--SKVTQALKIVIRD---IPGPPEGPVEI 7763 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + S+ SW P DGG+ + Y + DV++ W+ V+ + L Sbjct: 7764 SDIDSDACSLSWNKPLEDGGSNITNYVVEKCDVSRGDWV-TAVSSVSKTSCRLGKLIPGK 7822 Query: 2036 TYMIRIYARNEIGLSEPLESDEPFKVIP 2063 Y+ RI A N GLS+P++SD P Sbjct: 7823 EYVFRIRAENRFGLSDPIQSDRMVAKFP 7850 Score = 74.1 bits (174), Expect = 4e-11 Identities = 57/205 (27%), Positives = 88/205 (42%), Gaps = 11/205 (5%) Query: 1793 KNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTS 1848 ++GG PI +Y +E K+ K+W A R+Q L Y+FR+ A NE+GT Sbjct: 6157 RDGGKPITNYILEKKETMAKRWSRATREPLYPATQFRVQDLVEGCEYEFRVMAENELGTG 6216 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 P I + PS P + T SV+LKW P +G I Y++E+K Sbjct: 6217 DPSEPSKPILAKDPIVCPSPPVTPEAYDKTKDSVSLKWKLPRHDGKGRIFGYLVEYKKPG 6276 Query: 1909 GKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAENTVGVSLPT---ESQSV--RLEK 1961 W + + + + + E +FRI N G S P E V RLEK Sbjct: 6277 AVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYIREPIKVHDRLEK 6336 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTS 1986 + A + M+G++I +++ Sbjct: 6337 PELLLDANMARDHLAMLGTDITLSA 6361 Score = 73.7 bits (173), Expect = 5e-11 Identities = 67/288 (23%), Positives = 114/288 (39%), Gaps = 10/288 (3%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKK 1250 E P I ++L + A T L ++ + V W K V+ ++ T+ + Sbjct: 3151 EPPEIQLDVKLLAGLTARAGTKIELPADVKGKPAPRVKWTKADLVLRADDRVTIDTQPDH 3210 Query: 1251 RTLIIRKCTEDDQCEYT--CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 L I T D Y V + ++T + V +++ P ++ + Sbjct: 3211 SKLSIANTTRGDTATYIIEAVNVCGRATATIDVNILDKPGPPAAFDISEITSESCCLAWN 3270 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 P +IV S+ K + K S K + K+ I+++ EN G Sbjct: 3271 PPRDDGGSPITNYIVESRQTDKEEWIKLSATVKHTTFKACKLTGMKEYIFRISAENQFGI 3330 Query: 1369 ADVEMNVTILDKPS--PPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 + +V I+ K S PPG P + +I ++ + W EP+ G S I Y VE + + Sbjct: 3331 GEPAEHVPIVAKYSFDPPGSPTRVTPSDITKDAVTLTWFEPDEDGGSPITGYWVEKFDPE 3390 Query: 1424 TTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +WI + TS ++ L+T YRFR A N AS T+ Sbjct: 3391 SEKWIRCNKLPVKDTSFRVKGLRTKKKYRFRVLAENLAGPGKASSETD 3438 Score = 73.7 bits (173), Expect = 5e-11 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 22/314 (7%) Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRT 1252 P+I ++L E ++ A T L ++ + W I + + + Sbjct: 6509 PTIEVDVKLIEGVIAKAGTTIVLPAKMTGIPIPTAKWMTDGKDITSEGRCHIETAGSSTI 6568 Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L I +C D EY ++ + T L V V++ P V I + +++ Sbjct: 6569 LSISECQRGDTGEYVLIVTNPAGSKTVALHVTVLDLPGPPVG---PINILEVTPDYMMIQ 6625 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKP----SIDSKSASLTIKKVENTDAG---IYKLRLE 1363 ++A P+ + + + +++K KP S+ S S + T KV + G + ++R E Sbjct: 6626 WRA-PKDDGGTPITNYVVEKKDVKKPWEPWSVVSSSGTNTKAKVSRLEKGREYVVRVRAE 6684 Query: 1364 NNCG-HADVEMNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 N G +E TI + P PPG P +I +++ + W P+ G S I YV+E Sbjct: 6685 NKIGISTGLESPPTIAKHMFNPPGPPGLPVCSDITENAVTVEWTLPDYDGGSPISGYVIE 6744 Query: 1419 YQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E+ T +WI V + + + L +SY FR +A N ISD S ++ K + Sbjct: 6745 RREM-TGKWIRVNKTPVLDLRYRVSGLFEGNSYEFRVFAENIAGISDPSLASDPVKAARA 6803 Query: 1477 TKIQSPTVEKPLKN 1490 P L++ Sbjct: 6804 ITRPGPPGNPKLRD 6817 Score = 72.9 bits (171), Expect = 9e-11 Identities = 38/179 (21%), Positives = 73/179 (40%), Gaps = 1/179 (0%) Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 +T+ V +P P WI K + + LT+ D G Y L+LEN Sbjct: 2877 LTIRVPITGYPTPVARWIFGEKELNADERVSLVTKPTFTELTVAPSMRPDKGTYTLQLEN 2936 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + E+ V ++ PS P + E+ +++ W+ PE+ G S + +Y +E +E+ Sbjct: 2937 DISSVSGEVEVNVIACPSAPKDFKVAEVSRHHVHLMWEAPEHDGGSPVTHYQIEKREVSR 2996 Query: 1425 TEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 W+ V + + ++ ++ Y F A N+ + + E + + P Sbjct: 2997 KTWVKVASGVLDLEHTVTDVIEAKEYLFSVTACNKCGPGEPAYIDEPVNISSPATVPDP 3055 Score = 71.3 bits (167), Expect = 3e-10 Identities = 73/370 (19%), Positives = 149/370 (40%), Gaps = 30/370 (8%) Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADV-EM 1373 P ++V + +++ T S+D+ K + + ++++ EN+ G ++ E+ Sbjct: 3579 PITNYVVEKRDVRR--KTWQSVDTTVKDLKYIVSPLNEGSLYVFRVAAENSVGMSEFCEL 3636 Query: 1374 NVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 +L K P PP +LE+ + + W+ P++ G I YV+E +E T W+ Sbjct: 3637 EDAVLAKDTFTTPGPPYALTVLEVTKRHVELKWEAPKSDGGRPITKYVIEKKEKLGTRWL 3696 Query: 1429 S-VKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 K K +Q + ++ S +F+ A NE + D SE TE + T SP ++ Sbjct: 3697 KCCKTPDKQSQFKVTDVDEGSEVQFQVRAENEAGVGDPSEPTEILNIEDPTSAPSPPLDL 3756 Query: 1487 PLKNITTEP-NEDIELTCIFGGVP-----------QPKVTWYR-DGKKLKTAKATYENRX 1533 + + + E + GG P +P++ W R + + +K K ++ Sbjct: 3757 TIPDASREHITATWKPPAKDGGCPISGYHVEVAEARPELKWLRVNNRPIKELKFRIDD-- 3814 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVITISNEDIKQKHKVGDEWLV 1592 + D E+ P + + +DI G++ + Sbjct: 3815 GIKPEKKYVIRVRAINSVGTGDPSEITDKIFTKDPDSAPTLKLEAQDIVVIE--GEKLHL 3872 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + IP P ++W K+ + + D ++T + + + + + + + YTI N G Sbjct: 3873 KVPYKAIPTPTMVWQKDTLECKVDDRLSMTLEMNDAHLELLKCTHADAGTYTIVLKNALG 3932 Query: 1653 TSSVEVTLKV 1662 + V +KV Sbjct: 3933 MVTGTVNVKV 3942 Score = 66.9 bits (156), Expect = 6e-09 Identities = 40/137 (29%), Positives = 69/137 (50%), Gaps = 8/137 (5%) Query: 1594 AVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 A + G PPP+V W + G ++N ++ + + + + + + R S KY + + AG Sbjct: 7423 ATVRGRPPPKVTWRRMG--IDNVVRKGKVDIIDTMTFLLVPDSTRDDSGKYCLTVQSLAG 7480 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE----P 1708 +V V +KV D P P + +I + S + W PP +DGG E+ Y +EK E P Sbjct: 7481 EKAVFVNVKVLDTPG-PVMNLEATDIKQTSAMLSWTPPENDGGSEILHYIVEKREIDRKP 7539 Query: 1709 DNNRWIKVADVDRDVET 1725 D I+V ++ ++ T Sbjct: 7540 DPCEKIEVLEITKNSAT 7556 Score = 66.5 bits (155), Expect = 8e-09 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 1/84 (1%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 PS PRN VVSE TS S L W PE NGG+ I++Y++E K V + W + + Sbjct: 6380 PSPPRNLVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLM 6439 Query: 1926 CIENIKEKDEIIFRISAENTVGVS 1949 + + E + +FR++AEN G S Sbjct: 6440 AM-YLMEGIQYLFRVAAENQFGRS 6462 Score = 65.7 bits (153), Expect = 1e-08 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 3/148 (2%) Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKN 1432 + + P PP P I + ++ + W +P + G I Y++E+++ T +W+ ++ Sbjct: 9214 IAVAFPPGPPVNPRITDTTKTTATLNWGKPLDNGGLDITGYMIEHKKEGTEDWLKDTLSP 9273 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNI 1491 T+ + L+T + Y FR AVN + +ET+E ++I+ ++ L + + Sbjct: 9274 HRITEFVVAELETGAKYHFRISAVNSKGAGEPAETSELVEIIERASEPDLELDVELRRTL 9333 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 I L G P P VTW ++G Sbjct: 9334 VVRACCSIRLFVPIKGRPTPTVTWTKEG 9361 Score = 65.3 bits (152), Expect = 2e-08 Identities = 42/168 (25%), Positives = 76/168 (45%), Gaps = 6/168 (3%) Query: 1625 EKTSVIRIKELKRSH----SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 EK ++ + R H + T+ A+ + V K DKPS P +++ E++ Sbjct: 6335 EKPELLLDANMARDHLAMLGTDITLSATLKGVPTPVVSWKKNNDKPSPPRN-LVVSEVTS 6393 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 ES + WK P D+GG ++ Y +EK + +W+ V+ ++ + + L E +Y+FR Sbjct: 6394 ESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLMAMY-LMEGIQYLFR 6452 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 V A+N G S+ + ++ V P D V++ W Sbjct: 6453 VAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHHTDADKTEVWLAW 6500 Score = 65.3 bits (152), Expect = 2e-08 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 2/127 (1%) Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 H++ V P PP KP + ++D S + W P + G S II Y VE +E T W Sbjct: 9106 HSEAVKMVDRFGPPGPPSKPEVEKVDGHSATVTWRRPADDGGSDIIGYCVEKKEKKGTRW 9165 Query: 1428 I--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 + S K+I + + L + Y FR +A N + SE + + I P V Sbjct: 9166 VRASKKSIAELAFQVTGLAEDIEYEFRVFAENRAGFGEPSEPSMPVRTIAVAFPPGPPVN 9225 Query: 1486 KPLKNIT 1492 + + T Sbjct: 9226 PRITDTT 9232 Score = 64.9 bits (151), Expect = 2e-08 Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 9/193 (4%) Query: 1282 EVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 E++E P +D ++ ++ + L + P P W I + K I Sbjct: 7394 EILEAPEIDLDAMLKQGLTVRATCPIRLCATVRGRPPPKVTWR-RMGIDNVVRKGKVDII 7452 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 L + D+G Y L +++ G V +NV +LD P P +I +S + Sbjct: 7453 DTMTFLLVPDSTRDDSGKYCLTVQSLAGEKAVFVNVKVLDTPGPVMNLEATDIKQTSAML 7512 Query: 1400 CWDEPENTGNSTIIYYVVEYQEI----DTTEWISVKNITKTQTSIQNLK--TNSSYRFRA 1453 W PEN G S I++Y+VE +EI D E I V ITK ++ +K + + Sbjct: 7513 SWTPPENDGGSEILHYIVEKREIDRKPDPCEKIEVLEITKNSATVGWIKPARDGGAKIDG 7572 Query: 1454 YAVNEVDISDASE 1466 Y + +++ + E Sbjct: 7573 YVIEYIEVHEGEE 7585 Score = 62.5 bits (145), Expect = 1e-07 Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 15/177 (8%) Query: 1358 YKLRLENNCGHADV-EMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++ EN G D E + IL K PSPP P + S+++ W P + G Sbjct: 6205 FRVMAENELGTGDPSEPSKPILAKDPIVCPSPPVTPEAYDKTKDSVSLKWKLPRHDGKGR 6264 Query: 1412 IIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 I Y+VEY++ EWI S + + L Y FR + VN SD + Sbjct: 6265 IFGYLVEYKKPGAVEWIQANESPEQCPNLDFVVTGLNDGQEYVFRIFTVNAAGKSDPAYI 6324 Query: 1468 TEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 E KV +++ P + ++ DI L+ GVP P V+W ++ K Sbjct: 6325 REPIKV--HDRLEKPELLLDANMARDHLAMLGTDITLSATLKGVPTPVVSWKKNNDK 6379 Score = 61.7 bits (143), Expect = 2e-07 Identities = 64/286 (22%), Positives = 112/286 (39%), Gaps = 13/286 (4%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS----VLKITNV 700 V++GSDI + ++ P P + W +K D + V + ++ S L I Sbjct: 5554 VEQGSDISIIAKIRGCPFPTLTW-YKAPPHKSDNKVEVQYDEHINKIVSDDSCTLLIQQG 5612 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 K+ G YT++A N G+AS + L + G PP + + + L + G Sbjct: 5613 KRPDTGLYTLMASNSLGKASKEMRLNV-LGRPGPPSAPIKFEEIGAERITLSWLPPKDDG 5671 Query: 761 NPRPT--ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET-S 817 + T + W + +P S+ T+ + E V+ + A+N G+ E Sbjct: 5672 GSKVTNYVIWRRVANRKSWVPVTSEPKERIWTV-ENLMTGHEYVFRVMAQNKYGVGEPLD 5730 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 + V E L + +++ V G I+++A V+ P P ITW R+ + P Sbjct: 5731 SEPEVARDLYIGPEVDLDTSVKEKMVVHAGGVIRIIAYVSGQPTPDITWSRDGSALPPEA 5790 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + F +I S G Y A N+ G+ V + Sbjct: 5791 KVETTFIS---SALIIKPCSRKHLGVYTLTAKNAGGEKKKNVTVEV 5833 Score = 61.7 bits (143), Expect = 2e-07 Identities = 63/293 (21%), Positives = 107/293 (36%), Gaps = 12/293 (4%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW---KXXXXXXXXXARIQKLSINTTYQFR 1838 ++ + W +GGSP+I Y VE K+ W IQ L YQ R Sbjct: 8150 TISLAWTAPANDGGSPVIGYLVECKRANTADWIRCNIPRNLQETSYVIQNLIDKNEYQCR 8209 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 I A N +G S P K + P + + E + + G P Sbjct: 8210 ITAVNRVGFSEPVEVPGKHVAKDIIVAPEAVLSAELKEGLELNAGATMRLEATIKGRPRP 8269 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 K IV + +EN+ D + + E+ G+ + T + Sbjct: 8270 KITWAKMNTNIKDRQGIVIKSSNTDTIVMVENVNRYDAGKYIFNLESLAGMKMYT----I 8325 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 ++ + T P PP L ++ + W +P DGG + Y + RD + W + Sbjct: 8326 VVKVYDT-PGPP-VNLMVKETSKDGASIFWDSPLTDGGYEVTHYIVEKRDTERKAW-SIV 8382 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHAD 2070 ++ N F + DL+ +Y R+ N++G E E+ + + G+ D Sbjct: 8383 SMNCNKTSFEVPDLNAGRSYCFRVSGVNKLGAGEYCETADSVRASEEPGAVMD 8435 Score = 61.3 bits (142), Expect = 3e-07 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 17/232 (7%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E + AP F L P +G + +C V G P ++ W + +K S++ Q+ + D + Sbjct: 1 ESAQAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGS 60 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 V L + +AG + C A NAAG + + V+ V Sbjct: 61 VC-LEVEAASKTEAGDYLCKASNAAGSTFCKSRVSVK-----EKEFRAVPAEAVVPAIST 114 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVA 683 L+ + F ++PK E ++ P P++ W+ K +I P IS+ Sbjct: 115 PVRRLDNL--FFIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIH 172 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE----ASLPIVLKIKTGE 731 + + ++I V K GTY VA N+ GE A + + K + GE Sbjct: 173 HKGQ----DAKMEIREVTKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGE 220 Score = 60.9 bits (141), Expect = 4e-07 Identities = 62/286 (21%), Positives = 112/286 (39%), Gaps = 20/286 (6%) Query: 1639 HSSKYTIEASNTAGTSSVE-----VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 H +Y ++A N G SS VT K P P + + + ++ +VT+ W P+ Sbjct: 7259 HDYQYRVKAVNEIGISSPSKSSRAVTAKDAVGPPAPPSNLRVLDSTKSTVTLGWTKPVST 7318 Query: 1694 GGLELTKYAIEKH-----EPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 GG + Y +E + ++ W + V + + L++ Y FRV AQN V Sbjct: 7319 GGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQLVVCDFTVTSLDDQLVYEFRVSAQNQV 7378 Query: 1748 GFSEALESEPIVI-KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP--IIDYKV 1804 G S + + VI K L+ P + + + G P + ++ Sbjct: 7379 GMSLPCDLKDAVIPKEILEAPEIDLDAMLKQGLTVRATCPIRLCATVRGRPPPKVTWRRM 7438 Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864 I +K K + + + + ++ + ++ G + + K L Sbjct: 7439 GIDNVVRKGKVDIIDTMTFLLVPDSTRDDSGKYCLTVQSLAGEKAVFVNV------KVLD 7492 Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 P N ++ S L WT PE++GGS I +YI+E + + K Sbjct: 7493 TPGPVMNLEATDIKQTSAMLSWTPPENDGGSEILHYIVEKREIDRK 7538 Score = 60.1 bits (139), Expect = 7e-07 Identities = 92/411 (22%), Positives = 164/411 (39%), Gaps = 54/411 (13%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886 E+A+ P F + +TV E + L V +P + W ++ E+ S ET DG Sbjct: 1 ESAQAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDG- 59 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------------------- 924 ++ L + S+ ++GDY C ASN+AG + +RV++ Sbjct: 60 SVCLEV-EAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRR 118 Query: 925 VEKVTFVKHLQKSYETEEG-KTVILECQTSHTVSTKWYHNK-KEISGMDHREIIQEGRXX 982 ++ + F++ + TE+G T I + + KW K ++I+ I +G+ Sbjct: 119 LDNLFFIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDA 178 Query: 983 XXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV--KETIPEF--IR-KLQDFEVKEKD- 1032 D G +C+ ++ E S + V K+ + EF +R L+ K+K Sbjct: 179 KMEIREVTKSDSGTYRCVASNKHGEIECSAEMEVTKKQEVGEFGDVRVMLKKTPSKQKSP 238 Query: 1033 -------VAILEVEINSETADVVWERDGEIIKPKKNKYDF---EKRGHIRKLYIRNTSVH 1082 V +L E ++ E D + D EK K + V Sbjct: 239 KKEEWNIVELLRGHDPKEYEKILQEHDIHDYRAILQAMDLLKKEKEAEPSKTVDQVDRVE 298 Query: 1083 DEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF--EIELTKGDALVRWF 1140 +E I + ES + P ++ + +QK + ATF I++ + + W+ Sbjct: 299 EEDMARFIQQLES-----HIAAEPVSVLEDITDQKTAENQSATFRCRIQINYPEISLTWY 353 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 K ++ + +++ G LK+ DCD D G+Y G TA+L V Sbjct: 354 KGTRRLEQGHKYEISSVGDLHCLKVNDCDPSDEGDYRVVCGPHISTAMLAV 404 Score = 60.1 bits (139), Expect = 7e-07 Identities = 94/488 (19%), Positives = 186/488 (38%), Gaps = 34/488 (6%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKV 1662 W +G + E+ + N E T ++++L ++ + A N AG S T + + Sbjct: 5479 WDASGTQKEHWRRCNRRDVESTR-FKVEDLTYGDEYEFRVVAYNEAGPSRPSTTAGPITI 5537 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE---LTKYAIEKHEPDNNRWIKVAD- 1718 D+ P + ++E + G LT Y H+ DN ++ + Sbjct: 5538 QDQSCAPS--IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEH 5595 Query: 1719 ----VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 V D T IQ+ ++ ++A N +G ++ + L P Sbjct: 5596 INKIVSDDSCTLLIQQGKRPDTGLYTLMASNSLG-----KASKEMRLNVLGRPGPPSAPI 5650 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSIN 1832 I E + ++W P + +GGS + +Y + + +K W ++ L Sbjct: 5651 KFEEIGAERITLSWLPPKDDGGSKVTNYVIWRRVANRKSWVPVTSEPKERIWTVENLMTG 5710 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV-TLKWTEPES 1891 Y FR+ A+N+ G P S+ ++ + P V + + ++ S Sbjct: 5711 HEYVFRVMAQNKYGVGEPLDSEPEVARDLYIGPEVDLDTSVKEKMVVHAGGVIRIIAYVS 5770 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 +P + + + ++ + + ++ I+ K ++ ++A+N G Sbjct: 5771 GQPTPDITWSRDGSALPPEAKVETTFISSAL---IIKPCSRKHLGVYTLTAKNAGG---- 5823 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + ++V +E VP P P + ++ +W PE DGG+P+ Y + R+ + Sbjct: 5824 EKKKNVTVEV-LDVPGPVGIPFTTENLSNDSCKLNWFFPENDGGSPISNYIVEKREAERK 5882 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071 W V T L+ +Y R+ A N IG+ +E+ +V+ E E Sbjct: 5883 AWTSVSFTASRT-NAVAHGLTSGKSYFFRVAAENAIGIGPFVET--AAEVVIREPISIPE 5939 Query: 2072 EPGEQTEV 2079 P E+ EV Sbjct: 5940 RP-EELEV 5946 Score = 56.8 bits (131), Expect = 6e-06 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 DKPSPP + E+ S S + W PE+ G + I +YVVE +++ +W+ V K + Sbjct: 6378 DKPSPPRNLVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLS 6437 Query: 1439 SI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 + L Y FR A N+ SD T K + Sbjct: 6438 LMAMYLMEGIQYLFRVAAENQFGRSDFIVTKTPVKAV 6474 Score = 55.6 bits (128), Expect = 1e-05 Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 10/135 (7%) Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEM-------NVTILDKPSPPGKPNILEIDSSSINI 1399 +K V AG Y L L N +V++ N + +KP PP + + S SI I Sbjct: 4060 VKAVNKVGAGQY-LELRNPVITEEVKLPMYLLILNFDLTEKPDPPLQVETCDPTSKSITI 4118 Query: 1400 CWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 W P+N G I Y+VE ++ D E ++ + + LK N Y+FR A N Sbjct: 4119 TWKAPDNDGGCPIQGYIVEKIEKDGDRYERVTPSLVPGFSFVVTGLKENMEYQFRVRAEN 4178 Query: 1458 EVDISDASETTEYYK 1472 +S+ S +T+ K Sbjct: 4179 VAGVSEPSRSTQLLK 4193 Score = 53.2 bits (122), Expect = 8e-05 Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 13/150 (8%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-----WIS---VKN 1432 P+PP +L+ S++ + W +P +TG + II YVVE + + + W Sbjct: 7292 PAPPSNLRVLDSTKSTVTLGWTKPVSTGGAPIIGYVVEMRPQGSAKKGDDGWKRCNVAAQ 7351 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---K 1489 + ++ +L Y FR A N+V +S + + VI + +++P ++ + Sbjct: 7352 LVVCDFTVTSLDDQLVYEFRVSAQNQVGMSLPCDLKD--AVIPKEILEAPEIDLDAMLKQ 7409 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 +T I L G P PKVTW R G Sbjct: 7410 GLTVRATCPIRLCATVRGRPPPKVTWRRMG 7439 Score = 52.8 bits (121), Expect = 1e-04 Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 7/121 (5%) Query: 708 YTVVAVNREGEASLPIVLKIKT--GEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRP 764 + V+AVN G K T E EPP + ++ +I+R GES +L + G P P Sbjct: 6010 FRVIAVNEVGPGKPSFCTKPITCKDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPP 6069 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 +I W ++++ VKA + K+ T S+ ++K ++ + G Y + ENS G + +T Sbjct: 6070 SIAWYRDDEEVKADKHVMFKNTLTTMSLGLMKAQR-EHSGRYVVVVENSTGSRKGICNVT 6128 Query: 822 V 822 V Sbjct: 6129 V 6129 Score = 52.0 bits (119), Expect = 2e-04 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 2/140 (1%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQK-LSINTTYQ 1836 + +ES Y+TW E NGG+ I Y VE K ++W + + L Y Sbjct: 6391 VTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPVSAANKKLSLMAMYLMEGIQYL 6450 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FR+ A N+ G S + + L PP P+N +++ V L W P+ Sbjct: 6451 FRVAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHHTDADKTEVWLAWEWPDRTVPPT 6510 Query: 1897 ITNYIIEFKTVKGKSWTKIV 1916 I + + V K+ T IV Sbjct: 6511 IEVDVKLIEGVIAKAGTTIV 6530 Score = 51.2 bits (117), Expect = 3e-04 Identities = 41/130 (31%), Positives = 63/130 (48%), Gaps = 10/130 (7%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRN 859 + +KA N G E S IT + +E A P + I +F I +K+ I + A V Sbjct: 4766 FRVKAVNEVGDGEPSKAITAKIQDDELA-PVITILKFFKSNAIIIKKGSAIDIPAEVKGL 4824 Query: 860 PVPSITWYRNNEII-SPSETI----TQNFDGENIELVITNVDS-EIDSGDYKCVASNSAG 913 P+PS+ W +++ +I +P E T+ D + I ++ D G+YK VA N G Sbjct: 4825 PLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGNYKLVAENCFG 4884 Query: 914 KSSHGARVTI 923 K+ H RV I Sbjct: 4885 KAQHVIRVEI 4894 Score = 51.2 bits (117), Expect = 3e-04 Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 V +K+ PSPP L + V S +W PE +GGA + Y + +DV W+ V Sbjct: 6371 VSWKKNNDKPSPPRN-LVVSEVTSESAYLTWKAPEDNGGAVISHYVVEKKDVAAEQWVPV 6429 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI-----PGEGSHADE 2071 + L L E Y+ R+ A N+ G S+ + + P K + PG + Sbjct: 6430 SAAN-KKLSLMAMYLMEGIQYLFRVAAENQFGRSDFIVTKTPVKAVDPLYPPGPPKNLHH 6488 Query: 2072 EPGEQTEV 2079 ++TEV Sbjct: 6489 TDADKTEV 6496 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/121 (24%), Positives = 57/121 (47%), Gaps = 3/121 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A+N G++ + E E+ EP + + + ++ + +++ A V P P Sbjct: 7633 FRVAAKNLMGLSLFTETREPVEIKEQMLEPTILMP--ESVSARAGAKLRVEAVVAGKPAP 7690 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 W R + + PS + + G L+I +V S DSG+Y VA NS+ K + ++ Sbjct: 7691 MCKWMRGEDAVVPSSRLAVHQSGNLCVLIIKDV-SRTDSGEYSLVAENSSSKVTQALKIV 7749 Query: 923 I 923 I Sbjct: 7750 I 7750 Score = 50.0 bits (114), Expect = 7e-04 Identities = 48/141 (34%), Positives = 75/141 (53%), Gaps = 16/141 (11%) Query: 697 ITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTGEKEPP-QVIEPLKS--MIVRQGES 751 I N+ + QE + V AVN +GE S I KI+ E P +++ KS +I+++G + Sbjct: 4755 IENLSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELAPVITILKFFKSNAIIIKKGSA 4814 Query: 752 VILSAQVVGNPRPTITWCKNN----KPVK---ALPTKS-DGDTHSITILKPKKVK-DEGV 802 + + A+V G P P++ W K++ PV+ + T+ D T I P+ V+ D+G Sbjct: 4815 IDIPAEVKGLPLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGN 4874 Query: 803 YTLKAENSEGIAETSAVITVE 823 Y L AEN G A+ VI VE Sbjct: 4875 YKLVAENCFGKAQ--HVIRVE 4893 Score = 48.4 bits (110), Expect = 0.002 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIE----PLKSMIVRQGESVILSAQVVGNPRPT 765 VVA+N G + + + E + V+E K +I+R GE + L A V G P+P Sbjct: 4475 VVAINDAGPGAPGVTEPVMVKEPQESPVVEFDASVKKGVIIRAGEPLKLPAVVTGRPQPE 4534 Query: 766 ITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + W K+ + + +++G S+ I K + D G Y + NS G Sbjct: 4535 VKWAKDEGEIDKDRMIVETEGKNSSLFIKKTTRT-DHGKYKISGTNSSG 4582 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 + V N GE++ ++ E+ EP I+ + +V+ G+S+ + A V G P+P Sbjct: 6968 FRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVVKAGDSIPIEAMVKGKPQPD 7027 Query: 766 ITWCKNN--KPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W K+N + +K P +G S +L + D G Y + NS G A ++ Sbjct: 7028 VKWTKDNSTEEIKKGPRVQIENGTDFSKLLLTGARRTDSGKYVIAVTNSAGSCSAFATVS 7087 Query: 822 V 822 V Sbjct: 7088 V 7088 Score = 46.8 bits (106), Expect = 0.007 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 22/173 (12%) Query: 646 DEGSDILLECRLVAIPEPDIAWLF--KGEEIVPDENISVA-IESDMHMYCSVLKITNVKK 702 ++G ++ + A+ P +W+ + VP E +V +E D+H V+ Sbjct: 7974 NDGGSKIIGYYVEAMRVPGDSWIRCNTSSQNVPKEEYTVTGLERDLHYQFRVI------- 8026 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVV 759 T V +++ E + P+++ E PP++ + K + V+ G +VIL A+V Sbjct: 8027 ----AKTAVNISKPSEPTDPVLV---CAENVPPRLDLNVRMQKGLKVKAGATVILEAEVF 8079 Query: 760 GNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDE-GVYTLKAENS 810 G P P +TW + + +K+ + H + K+ GVYT+ AEN+ Sbjct: 8080 GKPMPRVTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKEHTGVYTILAENA 8132 Score = 46.8 bits (106), Expect = 0.007 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 3/84 (3%) Query: 742 KSMIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798 + + VR G++++++A ++G P PT W K K KA L T S +K K Sbjct: 8933 EGLTVRAGDTIVITATSILGKPTPTSCWSKGGKYFKASDLVQIETTPTSSTLSIKYATRK 8992 Query: 799 DEGVYTLKAENSEGIAETSAVITV 822 D G Y + A N G+ E + +TV Sbjct: 8993 DTGEYVITASNPFGVKEETVKVTV 9016 Score = 45.2 bits (102), Expect = 0.020 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 9/110 (8%) Query: 1358 YKLRLENNCGHADVEMNVTIL------DKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++R EN G ++ + +L DKP P EI ++S+ W+ PE+ G S Sbjct: 4172 FRVRAENVAGVSEPSRSTQLLKAADPVDKPGAPINFTFDEIRNTSVICNWEPPEDDGGSE 4231 Query: 1412 IIYYVVEYQEIDTTE--WISVKNITKTQT-SIQNLKTNSSYRFRAYAVNE 1458 I+ Y++E ++ E WI++ + K + + L Y FR A N+ Sbjct: 4232 ILNYILEKRDYKKEEVGWITITSTLKGNSFPVTKLIEGKEYIFRVTAENK 4281 Score = 44.0 bits (99), Expect = 0.046 Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 26/212 (12%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXX 1535 Q+P + PL+ +T E + L C G P KV W +D ++LK+++ T + Sbjct: 4 QAPKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCL 63 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK----------------PVITISNED 1579 Y C A N G V +++K PV + N Sbjct: 64 EVEAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFRAVPAEAVVPAISTPVRRLDNLF 123 Query: 1580 IKQKHK---VGDEWLVT--AVIEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIK 1633 ++ K ++ T A I G P P V W K ++ +I K + + + I+ Sbjct: 124 FIEEPKNISATEKGTATFIAKIGGEPIPNVKWMKGKWRQITPGGRISIHHKGQDAKMEIR 183 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 E+ +S S Y ASN G ++V K Sbjct: 184 EVTKSDSGTYRCVASNKHGEIECSAEMEVTKK 215 Score = 44.0 bits (99), Expect = 0.046 Identities = 59/278 (21%), Positives = 116/278 (41%), Gaps = 26/278 (9%) Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKV 797 L+ + + ++LS ++ + + W + K + A T KS+G S+ +LK + Sbjct: 1095 LQDFAATEKDELLLSCEL--SKDVPVVWYHSEKEITASKTVVLKSEGTCRSL-LLKRVEQ 1151 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 +G YT G +TSAV+ V+ + P + F + T + ++ Sbjct: 1152 SSKGTYTCDC----GTDKTSAVVDVQARDVKIVRPLYGVELF------DGETARFEVEIS 1201 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 + V W N +++S S + DG L++ N + +G+ A+N+ K S Sbjct: 1202 EDDVRG-QWKLNGDVLSRSPDVDIIEDGSKHTLILYNCRVAM-AGEVAYTAANA--KCSA 1257 Query: 918 GARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV-STKWYHNKKEISGMDHREI 975 +V + + +T + +Q YE +E + E + S S +W +E+ + E+ Sbjct: 1258 KLKVKELPLNFLTSLNDVQV-YEKDEAR---FEVELSRPPKSFRWLKGSQELQSDEKYEL 1313 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 IQEG D +D+ T+ L+++ Sbjct: 1314 IQEGHTYVLLIRSAIYEDEAKYMFEAEDKRTACKLILQ 1351 Score = 44.0 bits (99), Expect = 0.046 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 10/169 (5%) Query: 661 PEPDIAWLFKGEEIVPDENI--SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 P P + E++ P++ + + D+ + S LK + KF+ ++ ++ E Sbjct: 7589 PPPQPPVVEDEEDLEPEKEVWNTYTTVKDLKVSVSGLKESKRYKFRVAAKNLMGLSLFTE 7648 Query: 719 ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PV 775 P+ +K + E P ++ P +S+ R G + + A V G P P W + P Sbjct: 7649 TREPVEIKEQMLE---PTILMP-ESVSARAGAKLRVEAVVAGKPAPMCKWMRGEDAVVPS 7704 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 L G+ + I+K D G Y+L AENS + I + + Sbjct: 7705 SRLAVHQSGNL-CVLIIKDVSRTDSGEYSLVAENSSSKVTQALKIVIRD 7752 Score = 43.2 bits (97), Expect = 0.081 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ ++ E V G P P W R + PS ++ N+ L+I++V D+G ++ Sbjct: 7675 GAKLRVEAVVAGKPAPMCKWMRGEDAVVPSSRLAVH-QSGNLCVLIIKDVSRTDSGEYSL 7733 Query: 584 VAKNAAGFASSTTELIV 600 VA+N++ + ++++ Sbjct: 7734 VAENSSSKVTQALKIVI 7750 Score = 42.7 bits (96), Expect = 0.11 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 9/106 (8%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T ++QS AP +E GS + ++ G P P +TW++ K ++ YD Sbjct: 5536 TIQDQSCAPS-IELQEFMEVEQGSDISIIAKIRGCPFPTLTWYKAPP-HKSDNKVEVQYD 5593 Query: 562 D-------DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + D+ TL+I++ D G +T +A N+ G AS L V Sbjct: 5594 EHINKIVSDDSCTLLIQQGKRPDTGLYTLMASNSLGKASKEMRLNV 5639 Score = 42.7 bits (96), Expect = 0.11 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 6/125 (4%) Query: 704 QEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGESVILSAQVVG 760 +E TY V A+N GE A+ + + K P + L +M I ++G +V L + G Sbjct: 8495 KEYTYRVKAINDSGEGAAKELTVVAKDQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISG 8554 Query: 761 NPRPTITWCK-NNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 P P ++W K +++ +K ++ +++ + D YT+ NS GI E++ Sbjct: 8555 KPIPKVSWKKGDDEDLKDSGRVCAESSSVNTTLLIRDCQRNDASKYTITLRNSAGIKEST 8614 Query: 818 AVITV 822 I V Sbjct: 8615 IFIRV 8619 Score = 41.9 bits (94), Expect = 0.19 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 4/125 (3%) Query: 802 VYTLKAENSEGIAETSAVITVEEPTEEN-AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 +Y + + E++ V T E +E EP + I VK +I + A V P Sbjct: 6965 IYQFRVQTKNEGGESNWVTTAEVLVKEQIVEPEVKIKLDGTFVVKAGDSIPIEAMVKGKP 7024 Query: 861 VPSITWYRNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P + W ++N E I + Q +G + ++ DSG Y +NSAG S Sbjct: 7025 QPDVKWTKDNSTEEIKKGPRV-QIENGTDFSKLLLTGARRTDSGKYVIAVTNSAGSCSAF 7083 Query: 919 ARVTI 923 A V++ Sbjct: 7084 ATVSV 7088 Score = 41.5 bits (93), Expect = 0.25 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449 +I +S + W+ PE+ G S I Y +E +E ++ V + T ++++L N Y Sbjct: 3997 DITKNSCQVSWEMPEDDGGSPISSYTLERREASKKTYMPVLSGENVLTHTVKDLYVNCEY 4056 Query: 1450 RFRAYAVNEV 1459 FR AVN+V Sbjct: 4057 FFRVKAVNKV 4066 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + ++ +KL A VT P P + W ++ I I + +G+N L I + D Sbjct: 4513 VIIRAGEPLKLPAVVTGRPQPEVKWAKDEGEIDKDRMIVET-EGKNSSLFIKKT-TRTDH 4570 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G YK +NS+G S RV I Sbjct: 4571 GKYKISGTNSSGTKSAETRVDI 4592 Score = 40.7 bits (91), Expect = 0.43 Identities = 39/135 (28%), Positives = 62/135 (45%), Gaps = 11/135 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVI--EPLKSMIVRQGE 750 I N+ E + AVNR G S P+ + K K+ P V+ E + + + G Sbjct: 8197 IQNLIDKNEYQCRITAVNRVG-FSEPVEVPGKHVAKDIIVAPEAVLSAELKEGLELNAGA 8255 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 ++ L A + G PRP ITW K N +K + KS +T +I +++ D G Y Sbjct: 8256 TMRLEATIKGRPRPKITWAKMNTNIKDRQGIVIKS-SNTDTIVMVENVNRYDAGKYIFNL 8314 Query: 808 ENSEGIAETSAVITV 822 E+ G+ + V+ V Sbjct: 8315 ESLAGMKMYTIVVKV 8329 Score = 40.3 bits (90), Expect = 0.57 Identities = 41/155 (26%), Positives = 68/155 (43%), Gaps = 9/155 (5%) Query: 446 YILDTSNQDWWYVQKHLTEEKGW-VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSE 504 Y+L+ N D Y K L K A+ L++ YT Y K +N+ + ++ Sbjct: 8464 YVLEVLNGDDKY--KELMRSKNMQYSAKDLVEGKEYT-YRVKAINDSGEGAAKELTVVAK 8520 Query: 505 EQSMAPIFVEKLRPKH---TPDGSTVQFECQVEGYPRPQITWFR-QTAIIKPSQDFQMYY 560 +Q + P + P +GSTV+ + + G P P+++W + +K S Sbjct: 8521 DQIIHPNCDLRELPNMCYIAKEGSTVRLKIPISGKPIPKVSWKKGDDEDLKDSGRVCAES 8580 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 N TL+IR+ DA +T +N+AG ST Sbjct: 8581 SSVNT-TLLIRDCQRNDASKYTITLRNSAGIKEST 8614 Score = 39.9 bits (89), Expect = 0.75 Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 10/137 (7%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVL-KIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 K+ ++ E + VVA N G + I ++ IE + M V QG + + Sbjct: 5503 KVEDLTYGDEYEFRVVAYNEAGPSRPSTTAGPITIQDQSCAPSIELQEFMEVEQGSDISI 5562 Query: 755 SAQVVGNPRPTITWCK--NNKPVKALPTKSD-------GDTHSITILKPKKVKDEGVYTL 805 A++ G P PT+TW K +K + + D D +++ K D G+YTL Sbjct: 5563 IAKIRGCPFPTLTWYKAPPHKSDNKVEVQYDEHINKIVSDDSCTLLIQQGKRPDTGLYTL 5622 Query: 806 KAENSEGIAETSAVITV 822 A NS G A + V Sbjct: 5623 MASNSLGKASKEMRLNV 5639 Score = 39.9 bits (89), Expect = 0.75 Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 2/98 (2%) Query: 827 EENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 ++ EPP F++ I ++ + L R T P PSI WYR++E + + + Sbjct: 6033 KDELEPPTIELDFRDKIIIRVGESCLLQGRYTGKPPPSIAWYRDDEEVKADKHVMFKNTL 6092 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + L + E SG Y V NS G VT+ Sbjct: 6093 TTMSLGLMKAQRE-HSGRYVVVVENSTGSRKGICNVTV 6129 Score = 39.5 bits (88), Expect = 0.99 Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 8/109 (7%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P+ L+ VN+G K + + + L V+W KD E++ S Q+T L++ Sbjct: 6 PKFDVPLEPVTVNEGEKLSLKCHVIGSPPLKVQWMKDRRELKSSRETQITFVDGSVCLEV 65 Query: 1166 YDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPA 1210 +AG+Y C+ N+ C + ++V+E +P +VPA Sbjct: 66 EAASKTEAGDYLCKASNAAGSTFCKSRVSVKEKEFR---AVPAEAVVPA 111 Score = 39.5 bits (88), Expect = 0.99 Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 10/108 (9%) Query: 813 IAETSAVITV-EEPTE------ENAEPPLFIN-RFQE-ITVKEKGTIKLVARVTRNPVPS 863 IA+T+ I+ EPT+ EN P L +N R Q+ + VK T+ L A V P+P Sbjct: 8026 IAKTAVNISKPSEPTDPVLVCAENVPPRLDLNVRMQKGLKVKAGATVILEAEVFGKPMPR 8085 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 +TW R + + E + +L +T V E +G Y +A N+ Sbjct: 8086 VTWKRGDNSLKSCEGQVITHQRHHFQLEMTAVTKE-HTGVYTILAENA 8132 Score = 38.7 bits (86), Expect = 1.7 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 PT + + V EG + L+ AIP P + W E D+ +S+ +E +D H+ Sbjct: 3853 PTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKVDDRLSMTLEMNDAHL-- 3910 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 +LK T+ GTYT+V N G + + +K+ Sbjct: 3911 ELLKCTHA---DAGTYTIVLKNALGMVTGTVNVKV 3942 Score = 38.7 bits (86), Expect = 1.7 Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 12/142 (8%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIF-VEKLRPKHT---PDGSTVQF 529 + EN Q+ K +NE D P ++ +AP+ + K + GS + Sbjct: 4758 LSENQEYQFRVKAVNEVGDGEPSKAITAKIQDDELAPVITILKFFKSNAIIIKKGSAIDI 4817 Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV------ATLVIREVFPEDAGTFTC 583 +V+G P P + W + +I+ + +M + + + + I E +D G + Sbjct: 4818 PAEVKGLPLPSLQWVKDDVVIETPVEDKMIMETEEMDRTTLRTKIAIPETVRQDKGNYKL 4877 Query: 584 VAKNAAGFASSTTEL-IVEAPL 604 VA+N G A + I++ PL Sbjct: 4878 VAENCFGKAQHVIRVEILDRPL 4899 Score = 38.7 bits (86), Expect = 1.7 Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV-IREVFPEDAGTFT 582 G+T++ E ++G PRP+ITW + IK Q + N T+V + V DAG + Sbjct: 8254 GATMRLEATIKGRPRPKITWAKMNTNIKDRQG--IVIKSSNTDTIVMVENVNRYDAGKYI 8311 Query: 583 CVAKNAAGFASST 595 ++ AG T Sbjct: 8312 FNLESLAGMKMYT 8324 Score = 38.3 bits (85), Expect = 2.3 Identities = 24/105 (22%), Positives = 46/105 (43%) Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 T K+ + + P + ++ + G + L V Y+A P P W ++ K Sbjct: 3841 TDKIFTKDPDSAPTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKVDDRLS 3900 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 +++ A L + K + DAG Y + L+N G +NV ++ + Sbjct: 3901 MTLEMNDAHLELLKCTHADAGTYTIVLKNALGMVTGTVNVKVIGR 3945 Score = 37.9 bits (84), Expect = 3.0 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 D + +K +++ AP + + +G + + + P P + W + T K Sbjct: 3836 DPSEITDKIFTKDPDSAPTLKLEAQDIVVIEGEKLHLKVPYKAIPTPTMVWQKDTLECKV 3895 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 M + N A L + + DAGT+T V KNA G + T + V Sbjct: 3896 DDRLSMTLEM-NDAHLELLKCTHADAGTYTIVLKNALGMVTGTVNVKV 3942 Score = 37.5 bits (83), Expect = 4.0 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ V G P P ITW R + + P + + + L+I+ + G +T Sbjct: 5760 GGVIRIIAYVSGQPTPDITWSRDGSALPPEAKVETTFIS---SALIIKPCSRKHLGVYTL 5816 Query: 584 VAKNAAG 590 AKNA G Sbjct: 5817 TAKNAGG 5823 Score = 36.7 bits (81), Expect = 7.0 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 6/117 (5%) Query: 800 EGVYTLKAENS--EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 E Y +KA N EG A+ V+ ++ N + N KE T++L ++ Sbjct: 8496 EYTYRVKAINDSGEGAAKELTVVAKDQIIHPNCDLRELPNMCY--IAKEGSTVRLKIPIS 8553 Query: 858 RNPVPSITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P+P ++W + ++E + S + N L+I + D+ Y NSAG Sbjct: 8554 GKPIPKVSWKKGDDEDLKDSGRVCAESSSVNTTLLIRDCQRN-DASKYTITLRNSAG 8609 >UniRef50_Q86GD6 Cluster: Projectin; n=1; Procambarus clarkii|Rep: Projectin - Procambarus clarkii (Red swamp crayfish) Length = 8625 Score = 245 bits (600), Expect = 9e-63 Identities = 205/798 (25%), Positives = 314/798 (39%), Gaps = 39/798 (4%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 IK + + V + P+P W VN + + + K L I + TD+G Y Sbjct: 5282 IKVNTRLNYTVPIRGAPRPKVSWTVNGSPVVESERVDLQTYGKQTILDIPFAQRTDSGRY 5341 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 L LEN+ G VT L + G N+ ++ S + + P + G S I++Y+VE Sbjct: 5342 TLTLENDLGKVSASGTVTSLTSLTAEGPLNVYDVTRESCKVSFKTPIDDGGSPILHYLVE 5401 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 ++ W + + L Y FR AVN + S+ T+ + K + Sbjct: 5402 KMDVSRGTWTEAAEVAGLVAEVHGLVHMKEYHFRVKAVNAIGESEPL-CTDKSIIAKNAQ 5460 Query: 1479 IQSPTVEKPLKNITTEPNEDIELT--CIFGGVPQPKVTWYRDGKKLK------TAKATYE 1530 + +P + D+E T GG P +T Y KK + TA Sbjct: 5461 DEPSPPGRPNVVDWDSDHVDMEWTPPAHDGGAP---ITGYLIQKKERGSPYWQTAARVSG 5517 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKHKV 1586 ++ IA N G E S V+ + I + K Sbjct: 5518 PETKGTVPNLTEGQEYEFRIIAVNKAGNSEPSEPSDAVICRPRHLAPKILGPLYDVRIKA 5577 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G V G P P+V W+ + +L+ D IT SV+ R+ S +Y I Sbjct: 5578 GQVLHVDVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHTVNTMRNDSGEYRIR 5637 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 N +G + V D P PEGP++ E+ SV + WKPP+DDGG +T Y IEK Sbjct: 5638 VKNESGQDEATFQVIVLDTPGAPEGPLVYEEVQANSVVMSWKPPVDDGGSPITGYVIEKR 5697 Query: 1707 E-PDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE-PIVIKTA 1763 + W+ + VD + +L E +Y RV A+N G E LES+ P+ K++ Sbjct: 5698 DISHGGGWVPAVNWVDPKQNHATVPRLLEGTQYDSRVRAENMQGRGEPLESDRPVTAKSS 5757 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXXXXXX 1822 DVP D + + I W P GGSPI Y VE +WK Sbjct: 5758 ADVPGAPGRPSCTDS-DKDFIKIAWAPPRSTGGSPITGYDVERCGIHSGRWKKVNRDPVR 5816 Query: 1823 XARIQKLSIN--TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE--ST 1878 S+N YQ+R+ A N++G S P IT P + ++ + Sbjct: 5817 TTEFVDDSVNEGEQYQYRVVANNKMGPSNPSDPSQAITAKPMREAPKLYLDGLLGKKLKV 5876 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC---IENIKEKDE 1935 + P S P+ + + K ++ T + T +HC ++ + +D Sbjct: 5877 RAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTS----DHCRLFVDKARREDS 5932 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 F I+AEN G + + + ++K P PP PL V ++ V SW P+ +GG Sbjct: 5933 GTFTITAENPYGKD-SADIEVIVVDK----PGPPIGPLTPTEVTAHTVSLSWKPPQDNGG 5987 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 A + GY + T T E F ++ L E Y R+ A N G+SEPLE Sbjct: 5988 AEVTGY--VVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLEG 6045 Query: 2056 DEPFKVIPGEGSHADEEP 2073 P + A + P Sbjct: 6046 KPVEAKNPFDPPEAPDRP 6063 Score = 227 bits (555), Expect = 3e-57 Identities = 207/785 (26%), Positives = 332/785 (42%), Gaps = 47/785 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSK----IIKKCKHTKPS--IDSK--SASLTIKKV 1350 IK G +D P+P + W + K I+ + TK +DS + L I K Sbjct: 3206 IKVGQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKA 3265 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGN 1409 + +G Y L N G V++++TIL PS P P + ++ ++ + WD+PE+ G Sbjct: 3266 QRKMSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKANGCKLKWDKPEDDGG 3325 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +Y +E + T +W+ + + L+ Y+FR AVN S+ E + Sbjct: 3326 LPVDHYEIEKLDPITGQWMPCGESKTPEFDVTGLQEGKKYKFRVKAVNPEGESEPLEADK 3385 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNED-IELTCIF----GGVPQPK-VTWYRD--GKK 1521 +I + P+ KP K T + D +EL GG K + RD G+ Sbjct: 3386 --AIIAKNPFDPPS--KPGKPKATNWDRDFVELEWAKPKDDGGAEITKYIVEKRDVTGRG 3441 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKPVIT---ISN 1577 + NR ++ +A N G E S + KP I Sbjct: 3442 WTPCGSGPGNRTSIRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRFLAPRIDR 3501 Query: 1578 EDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 + + +K + G + + +EG P P+V W G ++N++ IT+++ + I I++ K Sbjct: 3502 KSVGRKTIRSGITFKNESKVEGEPDPKVTWSLQGAPIKNER-VTITSEDHLTTIVIRKAK 3560 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 RS + Y I A N +GT E+ L V KP KP+GP+ + +++ ES ++W+PP DDGG Sbjct: 3561 RSDTGVYKIFAKNDSGTDEAELDLIVIGKPGKPKGPLKVSDVTAESAKLKWEPPEDDGGE 3620 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 + Y +E+ + + RW+ V + + L E +Y FRV A N G SE LE++ Sbjct: 3621 PIDHYVVERMDTETGRWVPVKETKTPEAE--VPGLTEGKDYHFRVRAVNSEGESEPLETD 3678 Query: 1757 PIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK 1814 K D PS D + W E +GG+PI Y +E K + KW Sbjct: 3679 TATRAKNPYDPPS-KPGKPEVKDFDRTWCELKWKAPESDGGAPISHYVIERKDKYAAKWV 3737 Query: 1815 XXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 ++ L+ TYQFR+ A N+ G S P + D T P R Sbjct: 3738 KHCDTKSDKPEFKVNDLTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTN 3797 Query: 1873 VVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIEN 1929 + + + +K+ + N G PI + + + + H + I + Sbjct: 3798 LENITVRAGQMIKF---DCNVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIAS 3854 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 F I A+NT G T + + L+K P P PL++ + W Sbjct: 3855 CTRAHNGTFVIKADNTAGHDEVT-IEVIVLDK----PGKPEGPLKVSDIHKEGCTLKWKE 3909 Query: 1990 PEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 P DGGAP+ Y + D W+ VG+ T+ + +L H Y R+ A N G Sbjct: 3910 PLDDGGAPIEQYIVEKMDTETGRWVPVGRSREPTMA--VENLEPMHEYKFRVSAINSEGE 3967 Query: 2050 SEPLE 2054 SEPLE Sbjct: 3968 SEPLE 3972 Score = 221 bits (541), Expect = 1e-55 Identities = 211/832 (25%), Positives = 324/832 (38%), Gaps = 43/832 (5%) Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 L + +T + V+ PPKI R K G V+ P P +W++N K IK Sbjct: 4661 LPSDATHPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIK 4720 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-N 1388 T + + L + +G Y + EN G ++ V +LDKP P P Sbjct: 4721 PSSVTNIRYNDYNTKLRVTGATREQSGTYTIVAENANGKDSADVEVIVLDKPGTPQGPLK 4780 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTN 1446 + E+ + + W P + G I +YVVE + T W+ +T+ ++ L Sbjct: 4781 VSEVYAEGCKLDWKPPADDGGCPIDHYVVEQLDEATGRWVPAGETAGKETTFDVEGLTPG 4840 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC--- 1503 Y+FR AVN + SD T + + + P+ K + NI + ++L Sbjct: 4841 HKYKFRVKAVNRLGTSDPLVTQQAIEA--KNPFDPPSSPKDV-NIADFDCDFVDLEWKKP 4897 Query: 1504 -IFGGVPQPKVTWYRDGKK-----LKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDH 1556 GG P +T Y K+ L AT + ++ ++ +A N Sbjct: 4898 ETDGGAP---ITGYIIEKRDRYNPLWDKCATVDGDQCKAHVPDLLEGNVYEFRVVAINKA 4954 Query: 1557 GEVETS-----CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 G E S V + P N + K K GD + + G PP W N Sbjct: 4955 GPGEPSEPTKPHVARPKNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPATKQWRVRDN 5014 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 L +I ++ + I+I + KRS S +T+ A N G + V + V D P PEG Sbjct: 5015 DLYPSDRLSIINEDYMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITVLDVPGAPEG 5074 Query: 1672 PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKL 1731 PV I+R +I WKPP DDGG E+T Y +EK + + RW+ +V +D + + L Sbjct: 5075 PVKFSNINRNGCSIAWKPPKDDGGSEITSYVVEKMDMETYRWVPCGEV-KDTH-FQVDNL 5132 Query: 1732 NENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 E +Y FRV A N G + I K P+ D + V + W Sbjct: 5133 IEGHDYKFRVSAVNRQGQGPPCTGVDTITAKDPYSKPTKPGTPEVMDW-DKDRVDLQWTE 5191 Query: 1791 SEKNGGSPIIDYKVEIKQEGKKWKXXX---XXXXXXARIQKLSINTTYQFRIYARNEIGT 1847 +GG+PI + VE K+ W+ A + L+ YQFR+ A N+ G Sbjct: 5192 PRSDGGAPITGWIVEKKKRFGPWEKALELPAKHGPKASVPDLTEGEEYQFRVIAVNKAGN 5251 Query: 1848 SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 S P S + P + + L +T P P ++ + V Sbjct: 5252 SDPSDSSQPVVCKARFEKPGIDTKDLEDLIIKVNTRLNYTVPIRGAPRPKVSWTVNGSPV 5311 Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 + T G I + D + ++ EN +G + S +V T Sbjct: 5312 VESERVDLQTYGKQTILD-IPFAQRTDSGRYTLTLENDLG--KVSASGTVTSLTSLTA-- 5366 Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN 2027 PL + V S+ TP DGG+P+L Y + DV++ W E +V L Sbjct: 5367 --EGPLNVYDVTRESCKVSFKTPIDDGGSPILHYLVEKMDVSRGTWTEA--AEVAGLVAE 5422 Query: 2028 IRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 + L Y R+ A N IG SEPL +D+ +I PG V Sbjct: 5423 VHGLVHMKEYHFRVKAVNAIGESEPLCTDK--SIIAKNAQDEPSPPGRPNVV 5472 Score = 221 bits (539), Expect = 2e-55 Identities = 187/764 (24%), Positives = 306/764 (40%), Gaps = 36/764 (4%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 P P W +N K + ID + + I G + ++ +N GH +V Sbjct: 3819 PIPKKTWFIN-KARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHDEVT 3877 Query: 1373 MNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 + V +LDKP P P + +I + W EP + G + I Y+VE + +T W+ V Sbjct: 3878 IEVIVLDKPGKPEGPLKVSDIHKEGCTLKWKEPLDDGGAPIEQYIVEKMDTETGRWVPVG 3937 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 + +++NL+ Y+FR A+N S+ E + ++ + P + P K Sbjct: 3938 RSREPTMAVENLEPMHEYKFRVSAINSEGESEPLEGLD--TIVAKNPFDPP--DPPGKPE 3993 Query: 1492 TTEPNED-IELTCIF----GGVPQPKVTWYRDGKKLKTAKATYENRXXX---XXXXXXXX 1543 T+ ++D +EL G P + L + E + Sbjct: 3994 ATDWDKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLREVKGDTPKGRVNDLDEG 4053 Query: 1544 XXXXYKCIAFNDHGEVETS-CVVGIQQKP---VITISNEDIKQKH-KVGDEWLVTAVIEG 1598 ++ A N+ G + S + I KP I +++ + G+ L+ + G Sbjct: 4054 ETYEFRVRAVNEAGPSDPSEASLPITCKPRKLAPKIDRRNLRDLTVREGEPILLDVKVIG 4113 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 PPPEV W+ ++ K+ + + E R HS I A+N G E+ Sbjct: 4114 EPPPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVATNQHGRDEAEI 4173 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 T+ V KP KPEGP+ ++++ +E ++WKPP DDGG + Y +EK +PD W+ V Sbjct: 4174 TITVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYVVEKFDPDMGLWLPVGK 4233 Query: 1719 VDR-DVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXX 1776 D+E + L EY FRV A N G SE L + PI+ K VP Sbjct: 4234 TSTPDME---VTDLTPGHEYEFRVKAVNKEGESEPLVTLSPILAKDPFTVPGKPGAPEAT 4290 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLSINT 1833 D+ + + W ++GG+ I Y +E + + W+ + L Sbjct: 4291 DW-DSNHIDLKWSMPLEDGGAAISHYIIEKRDKYTNLWEKACETPTPECKGTATNLIEGM 4349 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 YQFRI A N G P I PP R + + S LK+ S Sbjct: 4350 EYQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKYDCDISGE 4409 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 P ++ E + ++ I + + + I + D + I+A N+ G T Sbjct: 4410 PPPTASWTYEGRKLEASRHVTIANIDYN-SKLVIRDTVRADSGEYVITATNSSGKDQVTV 4468 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 +V PSPP P+++ V W P+ DGG P+ Y + D +W Sbjct: 4469 RVTV-----TDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLW 4523 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + G+ + +LS Y R+ A N G S+PL ++E Sbjct: 4524 VPAGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEE 4567 Score = 220 bits (537), Expect = 4e-55 Identities = 187/786 (23%), Positives = 325/786 (41%), Gaps = 35/786 (4%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ IK G +V ++ + P P+ +W++ + +K ++D + + + Sbjct: 2612 KQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNT-KFNMIDAKRKQ 2670 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTII 1413 G YK+ N G + + + +L P P P + ++ S + WD+P++ G I Sbjct: 2671 TGTYKIIATNRDGKDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCKLKWDKPDDDGGKPIQ 2730 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 Y+VE Q+ T W+ V + L+ Y FR A+N+ S+ ET ++ + Sbjct: 2731 EYLVEKQDPTTGRWVPVGRTKDLAMDVPGLQEGKEYNFRVKAINDEGESEPLET-DHSTL 2789 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIF----GGVPQPKVTWYRDGKKLK--TAKA 1527 K+ P + + +I + ++L GG P +T Y KK + T + Sbjct: 2790 AKDP--YGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAP---ITKYIIEKKERYGTWET 2844 Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKPVITISNE 1578 +E+ + ++ +A N G + S KP+I + E Sbjct: 2845 IHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLI--NRE 2902 Query: 1579 DIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 +K+ + + + ++G PPPE+ W K+E Y I ++ + + + +R Sbjct: 2903 KLKKITTRASQKVFLEVDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAER 2962 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 H+ Y I A N +G+ E+ + V D+P KPEGP+ + ++ +E ++W+ P DDGGL Sbjct: 2963 RHTGIYKIHAKNDSGSDEAELEIIVLDRPGKPEGPLEISDVHKEGCKLKWEKPKDDGGLP 3022 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE- 1756 +T Y EK + + +W+ D D + L +Y FRV A N G S+ L+ + Sbjct: 3023 ITGYVAEKMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDEGESDPLDGDR 3082 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815 I+ K D P D SV + W P ++GG+ I Y +E+K + + Sbjct: 3083 AIIAKDPFDKPG-PPGLPEIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVE 3141 Query: 1816 XXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 + I L Y+FR+ A N+ G P S T P R V Sbjct: 3142 VGKVKGNVCQGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTARAKFRKPRIDRTNV 3201 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 + P + ++ K + ++VT + N K Sbjct: 3202 KDVVIKVGQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLL 3261 Query: 1934 -DEIIFRISAENTVGVSLPTESQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 + ++S + + + SV+++ PS P PLE+ V +N W PE Sbjct: 3262 IMKAQRKMSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKANGCKLKWDKPE 3321 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DGG P+ Y I D WM G + T +F++ L E Y R+ A N G SE Sbjct: 3322 DDGGLPVDHYEIEKLDPITGQWMPCG--ESKTPEFDVTGLQEGKKYKFRVKAVNPEGESE 3379 Query: 2052 PLESDE 2057 PLE+D+ Sbjct: 3380 PLEADK 3385 Score = 215 bits (524), Expect = 1e-53 Identities = 190/789 (24%), Positives = 316/789 (40%), Gaps = 46/789 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 IK G VDY P P+ W ++ ++I DAG+Y Sbjct: 2308 IKVGRSHKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLY 2367 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVV 1417 L++EN G + + +L KPS P P + + + + W++P++ G I Y V Sbjct: 2368 TLKIENRNGQDSETVELVVLGKPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEV 2427 Query: 1418 EYQEIDTTEWISVKN----ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 E ++ T +W+ + +++ L+ Y+FR AVN D D+ + Sbjct: 2428 EKMDLATGKWVRCGKCPGALAPPYFNVEGLEPGHQYKFRVTAVN--DEGDSDPLEADGAI 2485 Query: 1474 IKETKIQSPTVE-KPLKNITTEPNEDIELTCIF----GGVPQPKVTWYRDGKKLKTAKAT 1528 + + PT +P I N+ ++L GG P K + K + + Sbjct: 2486 LAKNPYDVPTAPGRP--EIVDYDNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVA 2543 Query: 1529 YENRXX------------XXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVI 1573 E + ++ +A N G E E + ++ K + Sbjct: 2544 AELKQDVIQPLKPGTPVETKVGGLKHRAEYQFRVVAVNKAGNSPESEPTDYHLVKHKALK 2603 Query: 1574 T-ISNEDIKQKH-KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 I +KQ K G IEG PPP V W +++ D I + + Sbjct: 2604 PRIDRTHLKQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVK-DSNIEIVNVDYNTKFN 2662 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 + + KR + Y I A+N G V + V P KP+GP+ + +++++S ++W P Sbjct: 2663 MIDAKRKQTGTYKIIATNRDGKDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCKLKWDKPD 2722 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DDGG + +Y +EK +P RW+ V +D+ + L E EY FRV A N G SE Sbjct: 2723 DDGGKPIQEYLVEKQDPTTGRWVPVGRT-KDL-AMDVPGLQEGKEYNFRVKAINDEGESE 2780 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811 LE++ + P D + V + W + GG+PI Y +E K+ Sbjct: 2781 PLETDHSTLAKDPYGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAPITKYIIEKKERYG 2840 Query: 1812 KWKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W+ R+ L TYQFR+ A N+ G P + K + K Sbjct: 2841 TWETIHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDP-SDPTKPHLAKARFLKPLI 2899 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSP--ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 + + T+R+ + E + G P I + K G ++ ++ + + + Sbjct: 2900 NREKLKKITTRASQKVFLEVDVKGEPPPEIWWTLKNKKVETGPNY--VIQAEDYLTKFTL 2957 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 + + + I++I A+N G S E + + L++ P P PLEI V W Sbjct: 2958 NDAERRHTGIYKIHAKNDSG-SDEAELEIIVLDR----PGKPEGPLEISDVHKEGCKLKW 3012 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P+ DGG P+ GY DVT W+ G+ D + + L Y R+ A N+ Sbjct: 3013 EKPKDDGGLPITGYVAEKMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDE 3072 Query: 2048 GLSEPLESD 2056 G S+PL+ D Sbjct: 3073 GESDPLDGD 3081 Score = 213 bits (519), Expect = 6e-53 Identities = 185/713 (25%), Positives = 294/713 (41%), Gaps = 53/713 (7%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-- 1436 DKP PPG P I++ D +S+ + WD P G + I YV+E + + ++ V + Sbjct: 3091 DKPGPPGLPEIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVEVGKVKGNVC 3150 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495 Q I LK Y FR AVN+ + + S++T + K + P +++ +K++ + Sbjct: 3151 QGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTA--RAKFRKPRIDRTNVKDVVIKV 3208 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA------------TYENRXXXXXXXXXXX 1543 + G P+P TW K L + + N Sbjct: 3209 GQQYLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKAQRK 3268 Query: 1544 XXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y A N+HGE ++G KP + D+K + +W G+P Sbjct: 3269 MSGKYVLTATNEHGEDSVKIDITILGPPSKPKGPLEVSDVKA-NGCKLKWDKPEDDGGLP 3327 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS----- 1655 V Y+ ++ + KT + L+ K+ ++A N G S Sbjct: 3328 ---VDHYEIEKLDPITGQWMPCGESKTPEFDVTGLQEGKKYKFRVKAVNPEGESEPLEAD 3384 Query: 1656 -VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + +D PSKP P R+ V +EW P DDGG E+TKY +EK + W Sbjct: 3385 KAIIAKNPFDPPSKPGKPKATNW-DRDFVELEWAKPKDDGGAEITKYIVEKRDVTGRGWT 3443 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXX 1773 + + I + + EY+FRV+A+N G SE + S+ ++ K P Sbjct: 3444 PCGSGPGNRTSIRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRFLAPRIDRKS 3503 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-----IQK 1828 I + IT+ K G P D KV +G K I+K Sbjct: 3504 VGRKTIRSG---ITFKNESKVEGEP--DPKVTWSLQGAPIKNERVTITSEDHLTTIVIRK 3558 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWT 1887 + T ++I+A+N+ GT D I IGK P +P+ VS+ T+ S LKW Sbjct: 3559 AKRSDTGVYKIFAKNDSGTD--EAELDLIVIGK----PGKPKGPLKVSDVTAESAKLKWE 3612 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 PE +GG PI +Y++E + W + E + + E + FR+ A N+ G Sbjct: 3613 PPEDDGGEPIDHYVVERMDTETGRWVPVKET--KTPEAEVPGLTEGKDYHFRVRAVNSEG 3670 Query: 1948 VSLPTESQSVRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 S P E+ + K+ PS P P E++ W PE DGGAP+ Y I + Sbjct: 3671 ESEPLETDTATRAKNPYDPPSKPGKP-EVKDFDRTWCELKWKAPESDGGAPISHYVIERK 3729 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 D W++ + +F + DL+E TY R+ A N+ G S+P ++ + F Sbjct: 3730 DKYAAKWVKHCDTKSDKPEFKVNDLTEGETYQFRVKAVNKAGQSKPSDASDNF 3782 Score = 212 bits (517), Expect = 1e-52 Identities = 158/603 (26%), Positives = 265/603 (43%), Gaps = 29/603 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQT 1438 PSPPG P + +I + +++ W PE+ G S I Y++E +E+ + W+ NI TQ Sbjct: 6852 PSPPGTPVVTKIGKNYVDLKWSVPESDGGSRITGYMIEKRELGSI-WMKCNDYNIVDTQY 6910 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 ++ NL S FR YA+N SD S++ + K+ + + P K L+N ++ Sbjct: 6911 TVLNLTEGSEVEFRVYAINAAGKSDPSQSAQPVKIREAAPGEKPFFVKNLQNTAVALHKS 6970 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTA-KATYEN---RXXXXXXXXXXXXXXXYKCIAFN 1554 + L C G P P W R+G+++ + T E + Y C+A N Sbjct: 6971 VTLECEAEGKPTPTARWLRNGREVTLGGRITSEESKGKFKLFISDMWEVDEGDYACVAAN 7030 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 D G+ + V I P IT + + GD + G P +V +NG +E Sbjct: 7031 DAGQATSIAHVKIGNPPRITQMQDALYLPE--GDNTKIKIYFTGDLPLDVTLSQNGLPVE 7088 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 + T ++ +I I+E+ + + +YT+ N +G+ + + + P P P+ Sbjct: 7089 ESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVKNDSGSVTGNFIVYITGVPGAPTAPLD 7148 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 + +ISR + W+PP+ DGGL +T Y +E+ + WI + +D ++ +Q L E Sbjct: 7149 VTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWITINSFCKDC-SFTVQGLTEG 7207 Query: 1735 CEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 EY+FRV+A N G L PI K D PS + + V++ W Sbjct: 7208 QEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPS-PPGTPNVTEVGGDFVHLEWDKPAH 7266 Query: 1794 NGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLP 1850 +GGS I Y VE ++ G W +I L + Y+FR++A N+ G S P Sbjct: 7267 DGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGMSEP 7326 Query: 1851 YTSDDKITI--GKTLTPP---SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 T + I TPP + RN + + S ++T + G P N I FK Sbjct: 7327 STCSTSVRIKDPNAATPPEIITPLRNVMALQHRSATLTCQ------IAGKPRPN-ISWFK 7379 Query: 1906 TVKG--KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 ++ S + G + + ++ +DE + A+N+ G+ S++L Sbjct: 7380 GMRELCNSAKYAMNRDGDTYTLTVHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKI 7439 Query: 1964 TVP 1966 VP Sbjct: 7440 NVP 7442 Score = 209 bits (511), Expect = 6e-52 Identities = 130/389 (33%), Positives = 195/389 (50%), Gaps = 10/389 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G+E+ +T P P+V W+ N++ +N ++++ + ++V K KRS KYT Sbjct: 6569 GEEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYT 6628 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I+ +N+ G S + V D+PS P+GP+ + +I+ ++ ++ W+PPLDDGG +T Y +E Sbjct: 6629 IKLTNSEGADSGSCKVNVVDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVE 6688 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTA 1763 + EP W+KV+ R Y + L N YMFRV A+N G S+ LE+ +PI K Sbjct: 6689 RLEPVTGMWVKVSAFVRSCH-YDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFP 6747 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXX--XXXX 1820 VP D SV +TW +GGS I YKVE + W Sbjct: 6748 FTVPDPPGRPNILDH-DINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVK 6806 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 + L IN Y+FR+ A+N G S KI + + PS P VV++ Sbjct: 6807 ETTYTVHSLLINHEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPSPPGTPVVTKIGKN 6866 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 V LKW+ PES+GGS IT Y+IE K G W K ++ + N+ E E+ FR+ Sbjct: 6867 YVDLKWSVPESDGGSRITGYMIE-KRELGSIWMKCNDYNIVDTQYTVLNLTEGSEVEFRV 6925 Query: 1941 SAENTVGVSLPTES-QSVRLEKHATVPSP 1968 A N G S P++S Q V++ + A P Sbjct: 6926 YAINAAGKSDPSQSAQPVKIREAAPGEKP 6954 Score = 204 bits (497), Expect = 3e-50 Identities = 163/687 (23%), Positives = 294/687 (42%), Gaps = 38/687 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + LQN V T E E K RW ++G E+ I T + K K K+ Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRI--TSEESKGKFKL 7011 Query: 1166 YDCDL--DDAGEYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 + D+ D G+Y+C N + T+I V+ + ++ + + +P + + + Sbjct: 7012 FISDMWEVDEGDYACVAANDAGQATSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFT 7071 Query: 1222 -DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTT 1277 D LDVT + +E+++ KFT+ + + IR+ + D +YT + D+ S T Sbjct: 7072 GDLPLDVTLSQNGLPVEESQRLKFTVFDEFI--IIFIREVVKQDAGQYTLTVKNDSGSVT 7129 Query: 1278 KLKVEVVEFPPKIVDYEREYR-IKRGS-DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 + + P + I R ++ P ++V K I Sbjct: 7130 GNFIVYITGVPGAPTAPLDVTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWIT 7189 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------DKPSPPGKPNI 1389 + K S T++ + ++++ N G V + D PSPPG PN+ Sbjct: 7190 INSFCKDCSFTVQGLTEGQEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPSPPGTPNV 7249 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNS 1447 E+ +++ WD+P + G S I Y VE +EI + W V TQ ++ NL + Sbjct: 7250 TEVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDR 7309 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 Y FR +A N+ +S+ S + ++ P + PL+N+ + LTC G Sbjct: 7310 QYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRNVMALQHRSATLTCQIAG 7369 Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX----YKCIAFNDHGEVETSC 1563 P+P ++W++ ++L + NR Y C A N G T Sbjct: 7370 KPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGEDEDEYMCRAQNSGGIRSTKA 7429 Query: 1564 VVGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + I+ P I + D K G+ ++ G P P + W + G +E+ Y++ Sbjct: 7430 DISIKLAPKINVPPRFRDTAFFDK-GENAVIKIPFIGNPRPRITWQREGETIESGGHYSV 7488 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 T+++ +++ ++++ + Y + A N G+ SV + +++ D+P P P + + E Sbjct: 7489 ETQQRHAILHLRDVTNLDTGNYRLTAENELGSDSVIIKIQISDRPDPPRLPKVESILGTE 7548 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 V + W+ PL DGG + Y IEK E WI+ ++ + T I+ L+ +Y FRV Sbjct: 7549 CV-LTWQIPLWDGGANINNYIIEKRELPMESWIRCSNT--RLTTAQIKGLSPGHKYQFRV 7605 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPS 1768 A+N G S+P + + ++ P+ Sbjct: 7606 YAENVYG-----RSDPSAVTSVVETPA 7627 Score = 188 bits (458), Expect = 1e-45 Identities = 126/465 (27%), Positives = 198/465 (42%), Gaps = 10/465 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G PPP W G KLE + I + S + I++ R+ S +Y I A+N++G Sbjct: 4406 ISGEPPPTASWTYEGRKLEASRHVTIANIDYNSKLVIRDTVRADSGEYVITATNSSGKDQ 4465 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V V + V DKPS PEGP+ + ++ ++WK P DDGG + Y +EK +P+ W+ Sbjct: 4466 VTVRVTVTDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLWVP 4525 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI-KTALDVPSXXXXXX 1774 + + L+ EY FRV A N G S+ L +E V+ K + P Sbjct: 4526 AGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPENLK 4585 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXARIQKLSIN 1832 D V + W P + +GG+PI Y VE K + W + L Sbjct: 4586 VADY-DQNKVDLKWEPPKSDGGAPIQKYIVEKKDKYGGWDKACEVPANKTSCSVPDLIEG 4644 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 TY+FR+ A N G LP + +T+ PP R ++ + + + S Sbjct: 4645 ETYEFRVRAVNPAGPGLPSDATHPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSG 4704 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 P +++ K +K S T I + +E+ + I AEN G Sbjct: 4705 EPVPEKKWLLNKKDIKPSSVTNIRYNDYNTKLRVTGATREQSG-TYTIVAENANGKD-SA 4762 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 + + + L+K P P PL++ V + W P DGG P+ Y + D Sbjct: 4763 DVEVIVLDK----PGTPQGPLKVSEVYAEGCKLDWKPPADDGGCPIDHYVVEQLDEATGR 4818 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 W+ G+ F++ L+ H Y R+ A N +G S+PL + + Sbjct: 4819 WVPAGETAGKETTFDVEGLTPGHKYKFRVKAVNRLGTSDPLVTQQ 4863 Score = 186 bits (452), Expect = 8e-45 Identities = 176/718 (24%), Positives = 284/718 (39%), Gaps = 45/718 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS- 1439 P PP P I + + + W P G + I Y+VEY++ D EW ++ T+ Sbjct: 6157 PGPPDAPRPDRIGRNCVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNY 6216 Query: 1440 -IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNE 1497 + L Y FR AVNEV S S + K+ E + P ++ +++ E Sbjct: 6217 TVLGLTELEEYYFRVIAVNEVGPSAPSRPSALIKI--EEQANKPRIDLSAVRDPPVRAGE 6274 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTA------KATYENRXXXXXXXXXXXXXXXYKCI 1551 D + + G P+P TWY D + + + ++ YK Sbjct: 6275 DFSIHVPYTGFPKPTSTWYHDDEDINIGADPRIHEKLTDDYCAMIVTNAQRSDTGPYKLR 6334 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW-LVTAVIEGIPPPEVIWYKNG 1610 N G S V + +P E+++ GD L + E+ Y Sbjct: 6335 LQNPSGFDSVSLNVRVLDRPA---PPENLRADEFNGDALTLFWNPPKDNGGAEITNYVVE 6391 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVTLK-VYD 1664 + +++ +RI+ L ++ + + A N G TS+ + + +D Sbjct: 6392 KREGRGNWTKVSSYVTAPFLRIRNLVVNNEYDFRVMAENQYGQSDPCTSANPIRARHPFD 6451 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 P P P + E + +S+TI+W P DGG + Y +EK +N W K + Sbjct: 6452 PPGAPGAPRGL-ESTEDSITIQWSKPRHDGGSHIQGYVVEKRIVGDNTWTKASHAMVKDT 6510 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVG---FSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 TY + L E+ EY FRV A N G +S+ E+ + A + S Sbjct: 6511 TYRVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCISFRAPKITSDLSIRDMTVIAGE 6570 Query: 1782 ESVYITWFPSEKNGGSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTY-QF 1837 E F + P + + + E+ + + + K + + ++ Sbjct: 6571 EFTITVPFIASPQ---PKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKY 6627 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 I N G + K+ + +PP P VS+ T + +L W P +GGSPI Sbjct: 6628 TIKLTNSEGAD---SGSCKVNVVDRPSPPQGPLE--VSDITPDTCSLAWRPPLDDGGSPI 6682 Query: 1898 TNYIIE-FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 TNY +E + V G W K+ S H + + ++ +FR+ AEN G+S P E+ Sbjct: 6683 TNYQVERLEPVTGM-WVKVSAFVRSCH-YDVMGLEPNRSYMFRVRAENQYGLSDPLETLD 6740 Query: 1957 VRLEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 K TVP PP P I N V+ +W P DGG+ + GY + RDVT T W Sbjct: 6741 PITAKFPFTVPDPPGRP-NILDHDINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAA 6799 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 V + + L NH Y R+ A+N G S + P K I +G ++ P Sbjct: 6800 ANDFLVKETTYTVHSLLINHEYEFRVKAKNAAGFS---KYSPPSKKIKMKGKYSVPSP 6854 Score = 183 bits (445), Expect = 5e-44 Identities = 206/876 (23%), Positives = 351/876 (40%), Gaps = 61/876 (6%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 DVTW + ++V+ +T++ + + + I T D YT + + VE+V Sbjct: 2327 DVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLKIENRNGQDSETVELVV 2386 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ----PNDEWIVNSKIIKKCKHTKPSIDSK 1341 K + + D + ++ P E+ V + K + Sbjct: 2387 LG-KPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEVEKMDLATGKWVRCGKCPG 2445 Query: 1342 SASLTIKKVENTDAGI-YKLRLE--NNCGHAD-VEMNVTIL-----DKPSPPGKPNILEI 1392 + + VE + G YK R+ N+ G +D +E + IL D P+ PG+P I++ Sbjct: 2446 ALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEADGAILAKNPYDVPTAPGRPEIVDY 2505 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-----------TKTQTSIQ 1441 D+ S+++ W PE+ G + I+ Y+V+ ++ +W + T +T + Sbjct: 2506 DNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVAAELKQDVIQPLKPGTPVETKVG 2565 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIE 1500 LK + Y+FR AVN+ S SE T+Y+ V + K P +++ LK T + +++ Sbjct: 2566 GLKHRAEYQFRVVAVNKAGNSPESEPTDYHLV--KHKALKPRIDRTHLKQTTIKAGRNVK 2623 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHG 1557 G P P V W +++K + N YK IA N G Sbjct: 2624 FDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNTKFNMIDAKRKQTGTYKIIATNRDG 2683 Query: 1558 EVETSCVVGIQQ---KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + E + + + KP + D+ +K +W G P E + K Sbjct: 2684 KDEAAVEIVVLSGPGKPKGPLKVSDVTKK-SCKLKWDKPDDDGGKPIQEYLVEKQD---P 2739 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEV---TLKV--YDKPSK 1668 + + K + + L+ + ++A N G S +E TL Y P K Sbjct: 2740 TTGRWVPVGRTKDLAMDVPGLQEGKEYNFRVKAINDEGESEPLETDHSTLAKDPYGPPGK 2799 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P P I+ + + V ++W+ P D GG +TKY IEK E W + + + + Sbjct: 2800 PGIPDIV-DWDVDRVDLKWEAPKDTGGAPITKYIIEKKERYGT-WETIHESEGPKTECRV 2857 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXID-NESVYI 1786 L E Y FRV+A N G + + ++P + K P ++ V++ Sbjct: 2858 PGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLINREKLKKITTRASQKVFL 2917 Query: 1787 TWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 K P I + ++ K + G + + T ++I+A+N+ Sbjct: 2918 E--VDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAERRHTGIYKIHAKND 2975 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 G+ ++ +I + L P +P +S+ LKW +P+ +GG PIT Y+ E Sbjct: 2976 SGSD---EAELEIIV---LDRPGKPEGPLEISDVHKEGCKLKWEKPKDDGGLPITGYVAE 3029 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 V W G + + ++ + FR+ A N G S P + + K Sbjct: 3030 KMDVTSGKWVPCGRTDGDATDLEVTGLEPGKKYEFRVKAVNDEGESDPLDGDRAIIAKDP 3089 Query: 1964 -TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 P PP P EI N V W P DGGA + GY + ++ ++EVGKV N Sbjct: 3090 FDKPGPPGLP-EIVDFDENSVKLKWDPPIRDGGAEITGYVLEMKPKNADNFVEVGKVKGN 3148 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + I L E Y R+ A N+ GL EP +S P Sbjct: 3149 VCQGPITGLKEGEKYEFRVRAVNKAGLGEPSDSTLP 3184 Score = 183 bits (445), Expect = 5e-44 Identities = 114/392 (29%), Positives = 176/392 (44%), Gaps = 12/392 (3%) Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 K K + G+ + + G P P W K G KLE K ++ T + + + +R S Sbjct: 5873 KLKVRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARREDS 5932 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 +TI A N G S ++ + V DKP P GP+ E++ +V++ WKPP D+GG E+T Sbjct: 5933 GTFTITAENPYGKDSADIEVIVVDKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAEVTG 5992 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760 Y +E+ P + + ++ L E +Y FRV A+N G SE LE +P+ Sbjct: 5993 YVVERPTPTTTYERSCQGTAK--PNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKPVEA 6050 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX 1820 K D P + + W P GG PI Y +E ++ G W Sbjct: 6051 KNPFD-PPEAPDRPDIVDYSPSTCSLEWKPPTDTGGRPITGYIIEKRERGGDWIRVNHYP 6109 Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT--IGKTLT-PPSQPRNFVVS 1875 + +Q LS Y+FRI A NE G P + I + K L PP PR + Sbjct: 6110 TPNTQYTVQGLSEGNRYEFRIIALNEAGPGKPSKPSNSIVAKVPKYLPGPPDAPRPDRIG 6169 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + VTL W P +GG+ I Y++E++ W ++ + + + E +E Sbjct: 6170 RN---CVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNYTVLGLTELEE 6226 Query: 1936 IIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 FR+ A N VG S P+ S +++E+ A P Sbjct: 6227 YYFRVIAVNEVGPSAPSRPSALIKIEEQANKP 6258 Score = 180 bits (438), Expect = 4e-43 Identities = 198/865 (22%), Positives = 356/865 (41%), Gaps = 56/865 (6%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF 1286 W KK +E +++ ++ + L + K +D +T + K + ++V VV+ Sbjct: 5898 WSKKGKKLEPSKRTSMETTSDHCRLFVDKARREDSGTFTITAENPYGKDSADIEVIVVDK 5957 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT----KPSIDSKS 1342 P + + T+ + ++ PQ N V ++++ T + + Sbjct: 5958 PGPPIGPLTPTEVTAH---TVSLSWKP-PQDNGGAEVTGYVVERPTPTTTYERSCQGTAK 6013 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-----LDKPSPPGKPNILEIDSSSI 1397 + T+K +E +++R EN G ++ + D P P +P+I++ S+ Sbjct: 6014 PNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKPVEAKNPFDPPEAPDRPDIVDYSPSTC 6073 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 ++ W P +TG I Y++E +E +WI V + TQ ++Q L + Y FR A Sbjct: 6074 SLEWKPPTDTGGRPITGYIIEKRE-RGGDWIRVNHYPTPNTQYTVQGLSEGNRYEFRIIA 6132 Query: 1456 VNEVDISDASETTEYYKVIKETKI-----QSPTVEKPLKNITT----EPNEDIELTCIFG 1506 +NE S+ + V K K +P ++ +N T P++D I G Sbjct: 6133 LNEAGPGKPSKPSNSI-VAKVPKYLPGPPDAPRPDRIGRNCVTLSWRPPSQDGGAK-IRG 6190 Query: 1507 GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG---EVETSC 1563 + + + +D + + A + ++ IA N+ G S Sbjct: 6191 YLVEYR---QKDEDEWQPANSLPHPDTNYTVLGLTELEEYYFRVIAVNEVGPSAPSRPSA 6247 Query: 1564 VVGIQQ---KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 ++ I++ KP I +S + G+++ + G P P WY + + + Sbjct: 6248 LIKIEEQANKPRIDLSAVR-DPPVRAGEDFSIHVPYTGFPKPTSTWYHDDEDINIGADPR 6306 Query: 1621 ITTK--EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 I K + + + +RS + Y + N +G SV + ++V D+P+ PE + E Sbjct: 6307 IHEKLTDDYCAMIVTNAQRSDTGPYKLRLQNPSGFDSVSLNVRVLDRPAPPEN-LRADEF 6365 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 + +++T+ W PP D+GG E+T Y +EK E N W KV+ I+ L N EY Sbjct: 6366 NGDALTLFWNPPKDNGGAEITNYVVEKREGRGN-WTKVSSY-VTAPFLRIRNLVVNNEYD 6423 Query: 1739 FRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV+A+N G S+ S PI + D P + +S+ I W +GGS Sbjct: 6424 FRVMAENQYGQSDPCTSANPIRARHPFDPPGAPGAPRGLESTE-DSITIQWSKPRHDGGS 6482 Query: 1798 PIIDYKVEIKQEG-KKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 I Y VE + G W R+ L+ + Y+FR+ A N G P++ Sbjct: 6483 HIQGYVVEKRIVGDNTWTKASHAMVKDTTYRVINLTEHQEYEFRVAAINAAGQG-PWSDP 6541 Query: 1855 DKITIGKTLTPPSQPRNFVVSEST-SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + + P + + + T T P P + I V + Sbjct: 6542 SENIKCISFRAPKITSDLSIRDMTVIAGEEFTITVPFIASPQPKVQWWIGPNEVIPDNRV 6601 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973 + + S + N K I + + + T + S V + PSPP PL Sbjct: 6602 QF-HMDSSNNSTVFVNKSAKRSDIGKYTIKLTNSEGADSGSCKVNVVDR---PSPPQGPL 6657 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033 E+ + + +W P DGG+P+ Y + + MW++V V + +++ L Sbjct: 6658 EVSDITPDTCSLAWRPPLDDGGSPITNYQVERLEPVTGMWVKVSAF-VRSCHYDVMGLEP 6716 Query: 2034 NHTYMIRIYARNEIGLSEPLESDEP 2058 N +YM R+ A N+ GLS+PLE+ +P Sbjct: 6717 NRSYMFRVRAENQYGLSDPLETLDP 6741 Score = 180 bits (437), Expect = 5e-43 Identities = 141/478 (29%), Positives = 203/478 (42%), Gaps = 28/478 (5%) Query: 1598 GIPPPEVIWYKNGNKLENDKE------YNITTKEKTSV----IRIKELKRSHSSKYTIEA 1647 G P P VIW K+ ++ D+E YN +S + +E + + A Sbjct: 2014 GEPEPRVIWKKDDKEVIPDEEQRLPEPYNCRRSPSSSSRGHSLHAEEGRSLRHRQVQASA 2073 Query: 1648 SNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 +T S E + V KP++PEGP+ EI + VT++WK PLDDGGL + Y IEK Sbjct: 2074 RSTLWASVKEEADVVVLGKPTRPEGPLFPEEIRADHVTLKWKKPLDDGGLPIEGYVIEKM 2133 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALD 1765 + D WI +V + + + + L +Y FRV A N G SE LE+ EPI+ + D Sbjct: 2134 DMDTGAWIPAGEVGPEKQEFTVDGLTPKKKYKFRVKAVNKEGESEPLENDEPILARNPYD 2193 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX-- 1822 PS DN V + W P E +GG PI Y +E+K + WK Sbjct: 2194 EPS-RPGKPEIIDYDNTMVVLRWTPPESDGGRPITHYHIEMKDKLSVDWKEVVQTKDTNC 2252 Query: 1823 XARIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNF-VVSESTSR 1880 A++ L T Y FR+ A N+ G +D+ + K P NF V+ R Sbjct: 2253 EAQVPGLKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGR 2312 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 S KW P + + I E I + KD ++ + Sbjct: 2313 S--HKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHT-EISITDATRKDAGLYTL 2369 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 EN G +S++V L PS P PLE+ V W P+ DGG P+ Sbjct: 2370 KIENRNG----QDSETVELVVLGK-PSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKE 2424 Query: 2001 YNIAIRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 Y + D+ W+ GK + FN+ L H Y R+ A N+ G S+PLE+D Sbjct: 2425 YEVEKMDLATGKWVRCGKCPGALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEAD 2482 Score = 177 bits (431), Expect = 3e-42 Identities = 140/476 (29%), Positives = 211/476 (44%), Gaps = 32/476 (6%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P+ W+ N + +ND+ I ++ + I I R+H+ + I+A NTAG Sbjct: 3815 VTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHD 3874 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 V + + V DKP KPEGP+ + +I +E T++WK PLDDGG + +Y +EK + + RW+ Sbjct: 3875 EVTIEVIVLDKPGKPEGPLKVSDIHKEGCTLKWKEPLDDGGAPIEQYIVEKMDTETGRWV 3934 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXX 1773 V R+ T ++ L EY FRV A N G SE LE + IV K D P Sbjct: 3935 PVGR-SRE-PTMAVENLEPMHEYKFRVSAINSEGESEPLEGLDTIVAKNPFDPPDPPGKP 3992 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKV----EIKQEGKKWKXXXXXXXXXARIQKL 1829 D + V + W K+ G+P + + G + + R+ L Sbjct: 3993 EATDW-DKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLR-EVKGDTPKGRVNDL 4050 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITI-GKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 TY+FR+ A NE G S P + IT + L P RN R +T++ E Sbjct: 4051 DEGETYEFRVRAVNEAGPSDPSEASLPITCKPRKLAPKIDRRNL-------RDLTVREGE 4103 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 P I E + GK K + +EN+ + I GV Sbjct: 4104 PILLDVKVIGEPPPEVEWFHGKKPIK------ETKDLRVENVPYNTKYINDEPLRKHSGV 4157 Query: 1949 S-LPTESQSVRLEKHATV-----PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 + + +Q R E T+ P P P+E++ V W P+ DGG+P+ GY Sbjct: 4158 TKIVATNQHGRDEAEITITVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYV 4217 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + D +W+ VGK +T + DL+ H Y R+ A N+ G SEPL + P Sbjct: 4218 VEKFDPDMGLWLPVGK--TSTPDMEVTDLTPGHEYEFRVKAVNKEGESEPLVTLSP 4271 Score = 173 bits (422), Expect = 3e-41 Identities = 207/871 (23%), Positives = 335/871 (38%), Gaps = 56/871 (6%) Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-- 1284 TW+ K+ ++ + I + RT ++I CT + + ++ +EV+ Sbjct: 3824 TWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGHDEVTIEVIVL 3883 Query: 1285 ------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 E P K+ D +E + + L D A P +++IV K+ + P Sbjct: 3884 DKPGKPEGPLKVSDIHKEGCTLKWKEP--LDDGGA---PIEQYIVE-KMDTETGRWVPVG 3937 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTIL-----DKPSPPGKPNILEI 1392 S+ ++ ++ +E +++ N+ G ++ +E TI+ D P PPGKP + Sbjct: 3938 RSREPTMAVENLEPMHEYKFRVSAINSEGESEPLEGLDTIVAKNPFDPPDPPGKPEATDW 3997 Query: 1393 DSSSINICWDEP-ENTGNSTIIYYV--VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 D + + W +P ++ G ++ + V + VK T + + +L +Y Sbjct: 3998 DKDFVELKWTKPAKDNGAPSLATSLRSVTNSLASGSRLREVKGDT-PKGRVNDLDEGETY 4056 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 FR AVNE SD SE + K K+ + L+++T E I L G P Sbjct: 4057 EFRVRAVNEAGPSDPSEAS-LPITCKPRKLAPKIDRRNLRDLTVREGEPILLDVKVIGEP 4115 Query: 1510 QPKVTWYRDGKKLKTAK-ATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P+V W+ K +K K EN K +A N HG E + Sbjct: 4116 PPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVATNQHGRDEAEITI 4175 Query: 1566 GIQQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + KP ++K HK G +W G P + K + D + Sbjct: 4176 TVISKPGKPEGPIEVKDVHKEGCKLKWKPPKDDGGSPVEGYV----VEKFDPDMGLWLPV 4231 Query: 1624 -KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK------VYDKPSKPEGPVIMR 1676 K T + + +L H ++ ++A N G S VTL + P KP P Sbjct: 4232 GKTSTPDMEVTDLTPGHEYEFRVKAVNKEGESEPLVTLSPILAKDPFTVPGKPGAPE-AT 4290 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 + + ++W PL+DGG ++ Y IEK + N W K + L E E Sbjct: 4291 DWDSNHIDLKWSMPLEDGGAAISHYIIEKRDKYTNLWEKACETPTPECKGTATNLIEGME 4350 Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y FR+ A N G E + S+ I+ K P I S + + + +G Sbjct: 4351 YQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGS--MLKYDCDISG 4408 Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSD 1854 P EG+K + KL I T R + + T+ + Sbjct: 4409 EPP---PTASWTYEGRKLEASRHVTIANIDYNSKLVIRDT--VRADSGEYVITATNSSGK 4463 Query: 1855 DKITIGKTLT-PPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 D++T+ T+T PS P + VS+ LKW P+ +GG+PI Y +E W Sbjct: 4464 DQVTVRVTVTDKPSPPEGPIKVSDVRGTGCKLKWKRPKDDGGTPIEYYQVEKLDPNTGLW 4523 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 G + N+ E FR+ A N G S P ++ L K Sbjct: 4524 VPAGRSAGPEPSVELNNLSPGTEYQFRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPEN 4583 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 L++ N V W P+ DGGAP+ Y + +D W + +V N ++ DL Sbjct: 4584 LKVADYDQNKVDLKWEPPKSDGGAPIQKYIVEKKD-KYGGWDKACEVPANKTSCSVPDLI 4642 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 E TY R+ A N G P ++ P V P Sbjct: 4643 EGETYEFRVRAVNPAGPGLPSDATHPVTVKP 4673 Score = 162 bits (393), Expect = 1e-37 Identities = 175/732 (23%), Positives = 301/732 (41%), Gaps = 51/732 (6%) Query: 1358 YKLRLENNCGHAD---VEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTGNST 1411 +++R N G +D E +V D PGKP L++ D + +++ W+ P++ G + Sbjct: 4549 FRVRAVNAEGESDPLNAEESVLAKDPYEEPGKPENLKVADYDQNKVDLKWEPPKSDGGAP 4608 Query: 1412 IIYYVVEYQEIDTTEWISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I Y+VE ++ W + KT S+ +L +Y FR AVN S+ T Sbjct: 4609 IQKYIVEKKD-KYGGWDKACEVPANKTSCSVPDLIEGETYEFRVRAVNPAGPGLPSDAT- 4666 Query: 1470 YYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 + V + K P +++ L + ++ + G P P+ W + K +K + T Sbjct: 4667 -HPVTVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVT 4725 Query: 1529 ---YEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584 Y + Y +A N +G+ V + KP + + + Sbjct: 4726 NIRYNDYNTKLRVTGATREQSGTYTIVAENANGKDSADVEVIVLDKPGTPQGPLKVSEVY 4785 Query: 1585 KVGD--EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 G +W A G P + + T ++T+ ++ L H K Sbjct: 4786 AEGCKLDWKPPADDGGCPIDHYVVEQLDEATGRWVPAGETAGKETT-FDVEGLTPGHKYK 4844 Query: 1643 YTIEASNTAGTSSVEVTLKV------YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + ++A N GTS VT + +D PS P+ V + + + V +EWK P DGG Sbjct: 4845 FRVKAVNRLGTSDPLVTQQAIEAKNPFDPPSSPK-DVNIADFDCDFVDLEWKKPETDGGA 4903 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +T Y IEK + N W K A VD D + L E Y FRV+A N G E E Sbjct: 4904 PITGYIIEKRDRYNPLWDKCATVDGDQCKAHVPDLLEGNVYEFRVVAINKAGPGEPSEPT 4963 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816 + ++P ID ++ + N P+ V K+W+ Sbjct: 4964 KPHVARPKNLPP---------RIDRNAMMDVKVKAGDNLNLPV--PVVGEPPATKQWRVR 5012 Query: 1817 XXXXXXXARIQKLSIN--TTYQFRIYARNEIG----TSLPYTSDDKITIGKT-LTPPSQP 1869 R+ ++ + TT + R++ G + +D T+ T L P P Sbjct: 5013 DNDLYPSDRLSIINEDYMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITVLDVPGAP 5072 Query: 1870 RNFVVSESTSRS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 V + +R+ ++ W P+ +GGS IT+Y++E ++ W V + + ++ Sbjct: 5073 EGPVKFSNINRNGCSIAWKPPKDDGGSEITSYVVEKMDMETYRWVPCGEVKDTHFQ--VD 5130 Query: 1929 NIKEKDEIIFRISAENTVGVSLP-TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 N+ E + FR+SA N G P T ++ + + P+ P P E+ + V W Sbjct: 5131 NLIEGHDYKFRVSAVNRQGQGPPCTGVDTITAKDPYSKPTKPGTP-EVMDWDKDRVDLQW 5189 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV-NTLKFNIRDLSENHTYMIRIYARNE 2046 P DGGAP+ G+ I + W + ++ + K ++ DL+E Y R+ A N+ Sbjct: 5190 TEPRSDGGAPITGW-IVEKKKRFGPWEKALELPAKHGPKASVPDLTEGEEYQFRVIAVNK 5248 Query: 2047 IGLSEPLESDEP 2058 G S+P +S +P Sbjct: 5249 AGNSDPSDSSQP 5260 Score = 160 bits (389), Expect = 3e-37 Identities = 172/715 (24%), Positives = 281/715 (39%), Gaps = 55/715 (7%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TKT 1436 D+PS PGKP I++ D++ + + W PE+ G I +Y +E ++ + +W V T Sbjct: 2193 DEPSRPGKPEIIDYDNTMVVLRWTPPESDGGRPITHYHIEMKDKLSVDWKEVVQTKDTNC 2252 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEP 1495 + + LK + Y FR A N+ I +ASE T+ + + + K + P +++ K++T + Sbjct: 2253 EAQVPGLKEGTVYSFRVKAANKAGIGEASEPTDNH--LCKHKNRKPRIDRTNFKSVTIKV 2310 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCI 1551 + + G P P VTW R L T + EN Y Sbjct: 2311 GRSHKWAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLK 2370 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD--EWLVTAVIEGIPPPEVIWYK- 1608 N +G+ + + + KP ++ H G +W G+P E K Sbjct: 2371 IENRNGQDSETVELVVLGKPSKPKGPLEVSNVHDTGCRLKWEKPDDDGGMPIKEYEVEKM 2430 Query: 1609 ---NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS------SVEVT 1659 G + K ++ L+ H K+ + A N G S + Sbjct: 2431 DLATGKWVRCGK---CPGALAPPYFNVEGLEPGHQYKFRVTAVNDEGDSDPLEADGAILA 2487 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 YD P+ P P I+ + +SV ++W P DGG + KY ++K + W A++ Sbjct: 2488 KNPYDVPTAPGRPEIV-DYDNKSVDLKWTVPESDGGAPIMKYIVQKKDKFMPDWEVAAEL 2546 Query: 1720 DRD----------VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI---VIKTALDV 1766 +D VET + L EY FRV+A N G S ESEP ++K Sbjct: 2547 KQDVIQPLKPGTPVETK-VGGLKHRAEYQFRVVAVNKAGNSP--ESEPTDYHLVKHKALK 2603 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826 P I ++ F G P V +QE K + Sbjct: 2604 PRIDRTHLKQTTI--KAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIEIVNVDYNTKF 2661 Query: 1827 QKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN-FVVSESTSRSVT 1883 + T ++I A N G D+ L+ P +P+ VS+ T +S Sbjct: 2662 NMIDAKRKQTGTYKIIATNRDG------KDEAAVEIVVLSGPGKPKGPLKVSDVTKKSCK 2715 Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 LKW +P+ +GG PI Y++E + W + + + ++E E FR+ A Sbjct: 2716 LKWDKPDDDGGKPIQEYLVEKQDPTTGRWVPVGRTKDLAMD--VPGLQEGKEYNFRVKAI 2773 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 N G S P E+ L K P +I + V W P+ GGAP+ Y I Sbjct: 2774 NDEGESEPLETDHSTLAKDPYGPPGKPGIPDIVDWDVDRVDLKWEAPKDTGGAPITKYII 2833 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ T W + + + + + L E +TY R+ A N+ G +P + +P Sbjct: 2834 EKKERYGT-WETIHESEGPKTECRVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKP 2887 Score = 155 bits (375), Expect = 2e-35 Identities = 151/643 (23%), Positives = 281/643 (43%), Gaps = 64/643 (9%) Query: 499 EKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 E+P +Q +AP F +K K G ++FEC++ PRP ITWFR ++ S Sbjct: 106 EQPVDIKQIDGLAPTFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARC 165 Query: 557 QMYYDDDN---VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 ++ + D T+ V EDAG + AKN G +++T L ++ S M + Sbjct: 166 KVTTEKDEKSYFVTMAFTNVTVEDAGKYKVTAKNELGESNATISLNFDS------SFMML 219 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 EG+ PTF+++P + ++G+ ++ CR VA P+P I W FKG++ Sbjct: 220 TADEVPSPK-------EGVRPTFTERPSIKQSEDGTSVIFSCRCVANPQPTIVWEFKGKK 272 Query: 674 IVPDENISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNR--EGEASLPIVLKIKTG 730 + + +E D +Y V L++ V EG Y VA N+ EG A++ + + KT Sbjct: 273 LREGARHRMKLEPDGKLYYMVILEVNKVTNADEGEYRAVASNKLGEGVATINLHFEGKTA 332 Query: 731 EKEPPQVIE------PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-----ALP 779 + P++ + P K I ++G+ +++ + NP P +TW K + ++ ++ Sbjct: 333 -SDKPKIPDGKAPRFPKKPEIRQEGDKLVMECILEANPEPEVTWFKGTEIIQEQGRISMY 391 Query: 780 TKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLF 835 K G S+TI+KP + D G + A N G + + + E+ P F Sbjct: 392 KKICGKDQFIVSVTIMKP-EASDGGQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTF 450 Query: 836 INRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETIT---QNFDGENIEL- 890 +++ I E GT I + R P P++ W+++ + + ++ + E E Sbjct: 451 LDK-PSIIPNESGTMITMKVRCKAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYS 509 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV------EKVTFVKHLQKSYETEEGK 944 I D+G YKCVA N G+++ + I+ + FV+ +E + G+ Sbjct: 510 CIVKDPCGADAGKYKCVAMNQFGEATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGR 569 Query: 945 TVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX----XDVGVIK 998 V++E + +++W + KE+ + + + D GV K Sbjct: 570 -VLMEALVRADPKPTSRWTKDGKELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYK 628 Query: 999 CIVKDQ--ETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEI 1055 C +K++ E + L + E P R + V + V I V I++ W +D Sbjct: 629 CNIKNEFGELNANLNLNIEVAPTIKRPPRIVSVFNRKVVIECVVISTSKPACSWFKDSSK 688 Query: 1056 IK-PKKNKYDFEKRG---HIRKLYIRNTSVHDEGEYSCILRDE 1094 ++ ++ + + G ++ ++ + D G Y + ++E Sbjct: 689 VRLDTRHCVNINEEGEGKYVVQMEMLKAEKMDCGSYKVVAKNE 731 Score = 147 bits (355), Expect = 4e-33 Identities = 180/750 (24%), Positives = 318/750 (42%), Gaps = 93/750 (12%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--- 563 + AP F +K + + DG+ + F+C++ P+P I WFR+ +K S ++ Sbjct: 4 NFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGKGG 63 Query: 564 NV--ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 N+ L++ +V EDAG + AKN G S++ L +E V Sbjct: 64 NIHDVQLILDDVEEEDAGLYKVKAKNKYGEVSASINLNFSP------NEQPVDIKQ---- 113 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 ++G+ PTF++KP + + G I ECR++A P P I W G ++ Sbjct: 114 -------IDGLAPTFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCK 166 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK------IKTGEK--E 733 V E D Y + TNV G Y V A N GE++ I L + T ++ Sbjct: 167 VTTEKDEKSYFVTMAFTNVTVEDAGKYKVTAKNELGESNATISLNFDSSFMMLTADEVPS 226 Query: 734 PPQVIEP--LKSMIVRQ---GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSD 783 P + + P + ++Q G SVI S + V NP+PTI W K ++ + + D Sbjct: 227 PKEGVRPTFTERPSIKQSEDGTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPD 286 Query: 784 GDTHSITILKPKKV--KDEGVYTLKAEN--SEGIAETSAVITVEEPTEENAEPPLFINRF 839 G + + IL+ KV DEG Y A N EG+A + + +++ P RF Sbjct: 287 GKLYYMVILEVNKVTNADEGEYRAVASNKLGEGVATINLHFEGKTASDKPKIPDGKAPRF 346 Query: 840 -QEITVKEKGTIKLVAR--VTRNPVPSITWYRNNEIISPSETIT--QNFDGENIELV-IT 893 ++ ++++G KLV + NP P +TW++ EII I+ + G++ +V +T Sbjct: 347 PKKPEIRQEGD-KLVMECILEANPEPEVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVT 405 Query: 894 NVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH------LQK-SYETEEGKT 945 + E D G ++C A N G S+ A + ++ EK + L K S E T Sbjct: 406 IMKPEASDGGQWRCNAFNPFGDSN--ANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGT 463 Query: 946 VI---LECQTSHTVSTKWYHNKKEISG-----MDHREIIQEGRXXXXXXXXXXXXDVGVI 997 +I + C+ + +W+ + K++ + ++ E D G Sbjct: 464 MITMKVRCKAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKY 523 Query: 998 KCIVKDQ---ETSTMLVVKETIPE-------FIRK-LQDFEVKEKDVAILEVEINSETAD 1046 KC+ +Q T+ + + E+ PE F+ K FE K V ++E + ++ Sbjct: 524 KCVAMNQFGEATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGRV-LMEALVRADPKP 582 Query: 1047 VV-WERDGEIIKPKK--NKYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDE--SCTAEV 1100 W +DG+ + + EK R ++ +R D G Y C +++E A + Sbjct: 583 TSRWTKDGKELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANL 642 Query: 1101 TV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH--IQLTID 1157 + +E+ P I + V + ++ WFKD S+++ + + + Sbjct: 643 NLNIEVAPTIKRPPRIVSVFNRKVVIECVVISTSKPACSWFKDSSKVRLDTRHCVNINEE 702 Query: 1158 GKKQ---KLKIYDCDLDDAGEYSCEVGNSK 1184 G+ + ++++ + D G Y N K Sbjct: 703 GEGKYVVQMEMLKAEKMDCGSYKVVAKNEK 732 Score = 146 bits (353), Expect = 8e-33 Identities = 90/308 (29%), Positives = 145/308 (47%), Gaps = 8/308 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW-KXXXXXXX 1821 +D PS I ++ + W P +GGSPI +Y+VE ++ W K Sbjct: 6647 VDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVERLEPVTGMWVKVSAFVRS 6706 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + L N +Y FR+ A N+ G S P + D IT T P P + + S Sbjct: 6707 CHYDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFPFTVPDPPGRPNILDHDINS 6766 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 V L W P S+GGS I Y +E++ V +W + + ++ E FR+ Sbjct: 6767 VVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVKETTYTVHSLLINHEYEFRVK 6826 Query: 1942 AENTVGVS-LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 A+N G S S+ ++++ +VPSPP P+ + +G N V W PE DGG+ + G Sbjct: 6827 AKNAAGFSKYSPPSKKIKMKGKYSVPSPPGTPV-VTKIGKNYVDLKWSVPESDGGSRITG 6885 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 Y I R++ ++WM+ ++ ++ + +L+E R+YA N G S+P +S +P K Sbjct: 6886 YMIEKRELG-SIWMKCNDYNIVDTQYTVLNLTEGSEVEFRVYAINAAGKSDPSQSAQPVK 6944 Query: 2061 V---IPGE 2065 + PGE Sbjct: 6945 IREAAPGE 6952 Score = 141 bits (342), Expect = 2e-31 Identities = 206/878 (23%), Positives = 338/878 (38%), Gaps = 76/878 (8%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288 W+ KK + K+ S+ TL+I K T DD +YT + + L V+ + Sbjct: 1336 WFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKYTVECMGIACSCILTVQEPDPDF 1395 Query: 1289 KIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLT 1346 K V ++ D TL + + W + I++ + + D + + LT Sbjct: 1396 KFVRPLPKKISSYTTKDATLEAQVNSH-KAIVHWFKGEEKIEEDEKFETYKDMTGTVRLT 1454 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 IK D G Y ++ C E ++I+D+P K ++ S ++ EN Sbjct: 1455 IKNASKKDKGKYTAKIFR-CEKEFTETLLSIVDQPFKFTK----QLKSKTVT------EN 1503 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 + I+ V+ E + + + +T ++ +K + +++ D + S Sbjct: 1504 S--KVILECDVDEAEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSISMDDAGNYSC 1561 Query: 1467 TTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 T + E +Q +K L++ T + P + W+ +GK++ T Sbjct: 1562 RTNADETTCEIIVQYENKFKKKLQDQMTYERQPATFEVELVD-PNAPLQWFINGKEV-TE 1619 Query: 1526 KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQQKPVITISNEDIKQ 1582 YE + ++ G +ET+C VG +KP E I+ Sbjct: 1620 GDNYEFQKKGGVHRLIIKEAATAHEGEIKAVCGNLETACQLSVGEGEKPPSIKPEEPIEG 1679 Query: 1583 KHKVGDEWLVTAVIEG--IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 + V I G I + K+G + N KE + +K + K+ R S Sbjct: 1680 PVTKPLVFEVPYTIPGARISKVDAKLLKDGKPM-NVKEVEVNILDKKVIYTFKKPSRDQS 1738 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 KYTI SN AG SS EV + + D+PS P V + EI S I + PP DDGGL LT Sbjct: 1739 GKYTIRMSNKAGESSKEVKINMQDRPSPPTN-VEVSEIFSTSCLITFGPPKDDGGLPLTY 1797 Query: 1701 YAIEKHE-----------PDNNRWIKVADVDRDVE-TYCIQKLNENCEYMFRVIAQNPVG 1748 Y IE+ + W +VA++ D + + L +Y F+V N +G Sbjct: 1798 YIIERQDFSVKASHPRIWERTGGWAQVAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLG 1857 Query: 1749 FSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 S+ + + I+ K D P + + W E +GG+PI Y +E + Sbjct: 1858 PSDPFIHPKVILAKDPWDEPGKILHVEVNDW-GPDHADLRWSRPETDGGAPITGYVIEFR 1916 Query: 1808 QEGKKWKXXXXXXXXXAR------------IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 A+ I L Y+FR+ A N+ G P Sbjct: 1917 TRAMPGAGEVDRFSDWAKGIEIQGDVTEGTIPDLKEGNQYEFRVRAVNKAGPGEPSDPTK 1976 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE----PESNGGSPITNYI---------- 1901 I P FV+++ +++ +K T+ GG P I Sbjct: 1977 PIQAKHRFVKP-----FVINKDEFKNIVIKKTQLFKLDVKYGGEPEPRVIWKKDDKEVIP 2031 Query: 1902 -IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 E + + + + + H E + + SA +T+ S+ E+ V L Sbjct: 2032 DEEQRLPEPYNCRRSPSSSSRGHSLHAEEGRSLRHRQVQASARSTLWASVKEEADVVVLG 2091 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 K T P P P EIR ++ V W P DGG P+ GY I D+ W+ G+V Sbjct: 2092 K-PTRPEGPLFPEEIR---ADHVTLKWKKPLDDGGLPIEGYVIEKMDMDTGAWIPAGEVG 2147 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 +F + L+ Y R+ A N+ G SEPLE+DEP Sbjct: 2148 PEKQEFTVDGLTPKKKYKFRVKAVNKEGESEPLENDEP 2185 Score = 139 bits (336), Expect = 9e-31 Identities = 128/535 (23%), Positives = 229/535 (42%), Gaps = 39/535 (7%) Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018 KW+ K E+ + EG D+G S +L V+E P+ Sbjct: 1335 KWFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKYTVECMGIACSCILTVQEPDPD 1394 Query: 1019 FI------RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 F +K+ + K+ A LE ++NS A V W + E I+ + ++ Sbjct: 1395 FKFVRPLPKKISSYTTKD---ATLEAQVNSHKAIVHWFKGEEKIEEDEKFETYKDMTGTV 1451 Query: 1073 KLYIRNTSVHDEGEYSC-ILRDESCTAE--VTVVELPPEIITRLQNQKVNKGNKATFEIE 1129 +L I+N S D+G+Y+ I R E E +++V+ P + +L+++ V + +K E + Sbjct: 1452 RLTIKNASKKDKGKYTAKIFRCEKEFTETLLSIVDQPFKFTKQLKSKTVTENSKVILECD 1511 Query: 1130 LTKGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188 + + +A V WF G ++ + I ++ DGKK++L +DDAG YSC + T Sbjct: 1512 VDEAEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSISMDDAGNYSCRTNADETTCE 1571 Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDV 1248 + V+ + F +L + + A VE+ D + W+ + + + + Sbjct: 1572 IIVQYEN-KFKKKLQDQMTYERQP-ATFEVELVDPNAPLQWFINGKEVTEGDNYEFQKKG 1629 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 LII++ + E V + ++ +L V E PP I + E I+ G L Sbjct: 1630 GVHRLIIKEAATAHEGEIKAVCGNLETACQLSVGEGEKPPSI---KPEEPIE-GPVTKPL 1685 Query: 1309 VDYQAFPQPNDEWI-VNSKIIK-----KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 V + P V++K++K K + +I K T KK +G Y +R+ Sbjct: 1686 VFEVPYTIPGARISKVDAKLLKDGKPMNVKEVEVNILDKKVIYTFKKPSRDQSGKYTIRM 1745 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 N G + E+ + + D+PSPP + EI S+S I + P++ G + YY++E Q+ Sbjct: 1746 SNKAGESSKEVKINMQDRPSPPTNVEVSEIFSTSCLITFGPPKDDGGLPLTYYIIERQDF 1805 Query: 1423 D-----------TTEWISVKNITKTQT---SIQNLKTNSSYRFRAYAVNEVDISD 1463 T W V I + ++L+ Y+F+ N++ SD Sbjct: 1806 SVKASHPRIWERTGGWAQVAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLGPSD 1860 Score = 129 bits (311), Expect = 9e-28 Identities = 87/325 (26%), Positives = 138/325 (42%), Gaps = 10/325 (3%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 F + A+NP G ++ + E IV+ D P + +V ++W P + NGG+ Sbjct: 5935 FTITAENPYG-KDSADIEVIVV----DKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAE 5989 Query: 1799 IIDYKVEIKQEGKKWKXXXXXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 + Y VE ++ ++ L Y+FR+ A N G S P + Sbjct: 5990 VTGYVVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLEGKP-V 6048 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 PP P + + + + +L+W P GG PIT YIIE K +G W ++ Sbjct: 6049 EAKNPFDPPEAPDRPDIVDYSPSTCSLEWKPPTDTGGRPITGYIIE-KRERGGDWIRVNH 6107 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR 1976 ++ ++ + E + FRI A N G P++ S S+ + +P PP AP R Sbjct: 6108 YPTPNTQYTVQGLSEGNRYEFRIIALNEAGPGKPSKPSNSIVAKVPKYLPGPPDAPRPDR 6167 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 +G N V SW P DGGA + GY + R + W + + + L+E Sbjct: 6168 -IGRNCVTLSWRPPSQDGGAKIRGYLVEYRQKDEDEWQPANSLPHPDTNYTVLGLTELEE 6226 Query: 2037 YMIRIYARNEIGLSEPLESDEPFKV 2061 Y R+ A NE+G S P K+ Sbjct: 6227 YYFRVIAVNEVGPSAPSRPSALIKI 6251 Score = 127 bits (306), Expect = 4e-27 Identities = 127/529 (24%), Positives = 202/529 (38%), Gaps = 35/529 (6%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKT 1436 D P PG P LE SI I W +P + G S I YVVE + + W + + T Sbjct: 6451 DPPGAPGAPRGLESTEDSITIQWSKPRHDGGSHIQGYVVEKRIVGDNTWTKASHAMVKDT 6510 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + NL + Y FR A+N S+ +E K I + T + ++++T Sbjct: 6511 TYRVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCI-SFRAPKITSDLSIRDMTVIAG 6569 Query: 1497 EDIELTCIFGGVPQPKVTWY------RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC 1550 E+ +T F PQPKV W+ +++ + N Y Sbjct: 6570 EEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYTI 6629 Query: 1551 IAFNDHGEVETSCVVGIQQKP--------VITISNEDIKQKHKV----GDEWLVTAVIEG 1598 N G SC V + +P V I+ + + G + +E Sbjct: 6630 KLTNSEGADSGSCKVNVVDRPSPPQGPLEVSDITPDTCSLAWRPPLDDGGSPITNYQVER 6689 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + P +W K + Y++ E + R+ + + T + + Sbjct: 6690 LEPVTGMWVK-VSAFVRSCHYDVMGLEPNRSYMFR--VRAENQYGLSDPLETLDPITAKF 6746 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 V D P +P ++ +I+ SV + W P DGG ++ Y +E + + W D Sbjct: 6747 PFTVPDPPGRPN--ILDHDIN--SVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAAND 6802 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXX 1777 TY + L N EY FRV A+N GFS+ + S+ I +K VPS Sbjct: 6803 FLVKETTYTVHSLLINHEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPS-PPGTPVVT 6861 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTY 1835 I V + W E +GGS I Y +E ++ G W + + L+ + Sbjct: 6862 KIGKNYVDLKWSVPESDGGSRITGYMIEKRELGSIWMKCNDYNIVDTQYTVLNLTEGSEV 6921 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 +FR+YA N G S P S + I + P +P F V + +V L Sbjct: 6922 EFRVYAINAAGKSDPSQSAQPVKI-REAAPGEKP--FFVKNLQNTAVAL 6967 Score = 120 bits (289), Expect = 4e-25 Identities = 147/634 (23%), Positives = 257/634 (40%), Gaps = 62/634 (9%) Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528 V A+ + E+N T + + L E P+ +E + P F E+ K + DG++V Sbjct: 195 VTAKNELGESNAT--ISLNFDSSFMMLTADEVPSPKE-GVRPTFTERPSIKQSEDGTSVI 251 Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN----VATLVIREVFPEDAGTFTCV 584 F C+ P+P I W + ++ +M + D + L + +V D G + V Sbjct: 252 FSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVTNADEGEYRAV 311 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 A N G +T L E + + I +G P F KKP+ + Sbjct: 312 ASNKLGEGVATINLHFEGKTASDKPK-----------------IPDGKAPRFPKKPEIR- 353 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIE-SDMHMYCSVLKITNVKK 702 EG +++EC L A PEP++ W FKG EI+ ++ IS+ + + + I + Sbjct: 354 -QEGDKLVMECILEANPEPEVTW-FKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEA 411 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEP----PQVIEPLKSMIVRQGESVILSAQV 758 G + A N G+++ I L + G+ P P ++ + G + + + Sbjct: 412 SDGGQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRC 471 Query: 759 VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSI----TILKPKKVKDEGVYTLKAENSE 811 P+PT+ W K+ K ++A L K T + I+K D G Y A N Sbjct: 472 KAKPQPTVEWFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQF 531 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK-GTIKLVARVTRNPVPSITWYRNN 870 G A + + +E E + P+F+ + I +EK G + + A V +P P+ W ++ Sbjct: 532 GEATANVNLNIESDPEPTGQAPVFVEK-PTIKFEEKAGRVLMEALVRADPKPTSRWTKDG 590 Query: 871 ---EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ + T+T+ D + D G YKC N G+ + A + +++E Sbjct: 591 KELDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELN--ANLNLNIEV 648 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREII---QEGR-- 980 +K + K V++EC T + W+ + ++ +D R + +EG Sbjct: 649 APTIKRPPRIVSVFNRK-VVIECVVISTSKPACSWFKDSSKVR-LDTRHCVNINEEGEGK 706 Query: 981 -XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 D G K + K+++ T + L++ E K+K+ E Sbjct: 707 YVVQMEMLKAEKMDCGSYKVVAKNEKGETTFAGRGA--HHRDMLEEKEEKKKEEVKEEKM 764 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 E A V E E KK+K KR I+K Sbjct: 765 EQQEAAQVEEESKKEEKAVKKDK---PKRREIKK 795 Score = 109 bits (263), Expect = 6e-22 Identities = 73/292 (25%), Positives = 127/292 (43%), Gaps = 13/292 (4%) Query: 1206 ILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 ++ + A LT +I + +++W+K + ++ K+ + D TL + +D+ Sbjct: 7353 VMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGEDED 7412 Query: 1265 EYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPND 1319 EY C ++ K ++ ++ PKI + +R +G + + + + P+P Sbjct: 7413 EYMCRAQNSGGIRSTKADISIKLAPKI-NVPPRFRDTAFFDKGENAVIKIPFIGNPRPRI 7471 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 W + I+ H + A L ++ V N D G Y+L EN G V + + I D Sbjct: 7472 TWQREGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELGSDSVIIKIQISD 7531 Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 +P PP P + I + + W P G + I Y++E +E+ WI N T Sbjct: 7532 RPDPPRLPKVESILGTECVLTWQIPLWDGGANINNYIIEKRELPMESWIRCSNTRLTTAQ 7591 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 I+ L Y+FR YA N SD S T + ET +P +KP K + Sbjct: 7592 IKGLSPGHKYQFRVYAENVYGRSDPSAVTS----VVET--PAPLTKKPKKKV 7637 Score = 97.9 bits (233), Expect = 3e-18 Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 8/218 (3%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 Q+ + +N+ G+ T + + I P+ P + V++ + L W P +GG Sbjct: 7116 QYTLTVKNDSGS---VTGNFIVYITGVPGAPTAPLD--VTDISRHMCNLAWRPPVYDGGL 7170 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954 P+T+Y++E K + +W I + ++ + E E +FR+ A N G+ P T Sbjct: 7171 PVTHYVVERKDITYANWITINSFCKDC-SFTVQGLTEGQEYLFRVMAVNENGMGPPLTGV 7229 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 ++ + PSPP P + VG + V W P DGG+ + GY + R++ +W Sbjct: 7230 NPIKAKAPYDPPSPPGTP-NVTEVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWT 7288 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 V + + N+ +L E+ Y R++A N+ G+SEP Sbjct: 7289 MVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGMSEP 7326 Score = 97.9 bits (233), Expect = 3e-18 Identities = 118/519 (22%), Positives = 198/519 (38%), Gaps = 33/519 (6%) Query: 1548 YKCIAFNDHGEVETSCVV---GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y ND G V + +V G+ P + DI +H W G+P Sbjct: 7117 YTLTVKNDSGSVTGNFIVYITGVPGAPTAPLDVTDIS-RHMCNLAWRPPVYDGGLPVTHY 7175 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-----TSSVEVT 1659 + + N N K+ + ++ L + + A N G T + Sbjct: 7176 VVERKDITYANWITINSFCKDCS--FTVQGLTEGQEYLFRVMAVNENGMGPPLTGVNPIK 7233 Query: 1660 LKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 K YD PS P P + E+ + V +EW P DGG + Y +EK E +N W V Sbjct: 7234 AKAPYDPPSPPGTPNVT-EVGGDFVHLEWDKPAHDGGSRIKGYWVEKREIGSNIWTMVNQ 7292 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK--TALDVPSXXXXXXX 1775 + L E+ +Y FRV A+N G SE S + IK A P Sbjct: 7293 YICLPTQINVSNLIEDRQYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRN 7352 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWKXXXXXXXXXARIQKLSINT 1833 + + S +T + K P I + +++ K+ + + Sbjct: 7353 VMALQHRSATLTCQIAGKP--RPNISWFKGMRELCNSAKYAMNRDGDTYTLTVHDVYGED 7410 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 ++ A+N G +D I + + P + R+ + +V P Sbjct: 7411 EDEYMCRAQNSGGIRST-KADISIKLAPKINVPPRFRDTAFFDKGENAVI---KIPFIGN 7466 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 P + E +T++ + T H + ++ D +R++AEN +G ++ Sbjct: 7467 PRPRITWQREGETIESGGHYSVETQQRHAILH-LRDVTNLDTGNYRLTAENELG----SD 7521 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S ++++ + P PP P ++G+ V+T W P WDGGA + Y I R++ W Sbjct: 7522 SVIIKIQI-SDRPDPPRLPKVESILGTECVLT-WQIPLWDGGANINNYIIEKRELPMESW 7579 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + + T + I+ LS H Y R+YA N G S+P Sbjct: 7580 IRCSNTRLTTAQ--IKGLSPGHKYQFRVYAENVYGRSDP 7616 Score = 96.7 bits (230), Expect = 6e-18 Identities = 78/317 (24%), Positives = 152/317 (47%), Gaps = 33/317 (10%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM- 688 + P+F++KPK + D+G+ ++ +C+L A P+P I W + + + + ++ Sbjct: 3 DNFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGKG 62 Query: 689 -HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQV--IEP--L 741 +++ L + +V++ G Y V A N+ GE S I L E+ + Q+ + P Sbjct: 63 GNIHDVQLILDDVEEEDAGLYKVKAKNKYGEVSASINLNFSPNEQPVDIKQIDGLAPTFA 122 Query: 742 KSMIVRQ---GESVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITI-L 792 + +++Q G+ + +++ +PRPTITW ++ V+ + T+ D ++ +T+ Sbjct: 123 QKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCKVTTEKDEKSYFVTMAF 182 Query: 793 KPKKVKDEGVYTLKAENSEGIAETS---------AVITVEE-PTEENAEPPLFINRFQEI 842 V+D G Y + A+N G + + ++T +E P+ + P F R I Sbjct: 183 TNVTVEDAGKYKVTAKNELGESNATISLNFDSSFMMLTADEVPSPKEGVRPTFTER-PSI 241 Query: 843 TVKEKGT-IKLVARVTRNPVPSITW-YRNNEIISPS-ETITQNFDGENIELVITNVD--S 897 E GT + R NP P+I W ++ ++ + + DG+ +VI V+ + Sbjct: 242 KQSEDGTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVT 301 Query: 898 EIDSGDYKCVASNSAGK 914 D G+Y+ VASN G+ Sbjct: 302 NADEGEYRAVASNKLGE 318 Score = 96.7 bits (230), Expect = 6e-18 Identities = 144/662 (21%), Positives = 249/662 (37%), Gaps = 68/662 (10%) Query: 466 KGWVPAQYLMDENNYTQYLQ-KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG 524 K W A++L+ +Y +KL+ +DK + + Q AP FV + + T +G Sbjct: 7967 KEW--AKFLLPIGRLAEYSSLRKLH--LDKYRIHDTHFDRRQC-APRFVIRPQNAFTYEG 8021 Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 +V+F C++ P + WF ++ S + Y ++ + VI V ED G + Sbjct: 8022 QSVKFSCRIVAVAAPTVCWFHNNMELRQSVKYMKRYSGEDYS-FVINRVKLEDRGEYIIR 8080 Query: 585 AKNAAGFASSTTELIVEAPLSDHGS----EMTVXXXXXXXXXXXXADILEGIPP-TFSKK 639 A+N G L V+ PL + + + EG P TF + Sbjct: 8081 AENHYGAREEPVFLNVQ-PLPPEAPPYRPQEQIIRRRQPLTYKLWQEEGEGAPSFTFLLR 8139 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ + +L C L P P + W +KG + + + S + + ++I N Sbjct: 8140 PRVIQCHQTCKLL--CCLAGKPVPTVKW-YKGSQELSKFDYSQSHADGV----VTIEIVN 8192 Query: 700 VKKFQEGTYTVVAVNREG--EASLPIVLK----IKTGEKEPPQVIEPLKSMIVRQGESVI 753 K G Y VA N G E S ++++ I+T K+ P P + S Sbjct: 8193 CKPADSGKYRCVATNSLGTDETSCVVIVEDRRYIETTIKDLPPPPTPAIRVDDTSSSSYF 8252 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 S G +++ K S + + + +K G K ++S G Sbjct: 8253 TSTHKDG---------RSSTSTKVEAASSSSTSSAAASGAKRTLKPYG----KRQDSTGS 8299 Query: 814 AETSAVITVE---EPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRN 869 S T E P + PP F + + +K+ + L V +P P ++W+++ Sbjct: 8300 TSRSRSATKELELPPDDSLMGPPGFSGELPKTLAIKDGEALCLKCTVKGDPEPQVSWFKD 8359 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV---- 925 E +S S+ I + L I V E D G Y C A++S G + +++I Sbjct: 8360 GEPLSSSDIIDLKYRQGLASLTINEVFPE-DEGLYVCKATSSLGSAETKCKLSISPMEQQ 8418 Query: 926 --------EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREI 975 +K+ + S E +G L C+ W HN+KEI Sbjct: 8419 INGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHNEKEIKPSKDFLY 8478 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKC-----IVKDQETSTMLVV----KETIPEFIRKLQDF 1026 + EG D G C + + T T+ V+ ++ P F + + Sbjct: 8479 VTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEKKQPAFKKFPRSQ 8538 Query: 1027 EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY-IRNTSVHDEG 1085 V E A V+ + V W +DG+ + ++ F++ G Y I + D G Sbjct: 8539 TVMEGKSATFSVKFEKDPLKVSWIKDGKPVDESSPRFKFQQEGKKEFSYEIPSCLPTDVG 8598 Query: 1086 EY 1087 +Y Sbjct: 8599 QY 8600 Score = 92.3 bits (219), Expect = 1e-16 Identities = 71/250 (28%), Positives = 103/250 (41%), Gaps = 6/250 (2%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 K K A FE E +K D+ +WF E+ + +G L I LDD G+Y Sbjct: 1314 KEGKDKFAKFEAEFSKKDSKPKWFFKKDELFTGAKYKFKSEGCVHTLVITKPTLDDMGKY 1373 Query: 1177 SCEVGNSKCTAILTVEE--PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234 + E C+ ILTV+E P F LP+ I DA L ++ V W+K + Sbjct: 1374 TVECMGIACSCILTVQEPDPDFKFVRPLPKKISSYTTKDATLEAQVNSHKAIVHWFKGEE 1433 Query: 1235 VIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVD 1292 IE+ EKF D+ L I+ ++ D+ +YT + K T+ + +V+ P K Sbjct: 1434 KIEEDEKFETYKDMTGTVRLTIKNASKKDKGKYTAKIFRCEKEFTETLLSIVDQPFKFTK 1493 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + + S V L D + EW K+ K K D K L K + Sbjct: 1494 QLKSKTVTENSKVILECDVDE-AEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFKSIS 1552 Query: 1352 NTDAGIYKLR 1361 DAG Y R Sbjct: 1553 MDDAGNYSCR 1562 Score = 89.4 bits (212), Expect = 9e-16 Identities = 63/230 (27%), Positives = 111/230 (48%), Gaps = 15/230 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKT-GEKEPPQVIEPLKSMIVRQGE 750 + ++N+ + ++ + V A N G ++ ++IK PP++I PL++++ Q Sbjct: 7300 INVSNLIEDRQYEFRVFAENDAGMSEPSTCSTSVRIKDPNAATPPEIITPLRNVMALQHR 7359 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 S L+ Q+ G PRP I+W K + + DGDT+++T+ +DE Y +A Sbjct: 7360 SATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLTV-HDVYGEDEDEYMCRA 7418 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSITW 866 +NS GI T A I+++ + N P RF++ +KG ++ NP P ITW Sbjct: 7419 QNSGGIRSTKADISIKLAPKINVPP-----RFRDTAFFDKGENAVIKIPFIGNPRPRITW 7473 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 R E I + + L + +V + +D+G+Y+ A N G S Sbjct: 7474 QREGETIESGGHYSVETQQRHAILHLRDV-TNLDTGNYRLTAENELGSDS 7522 Score = 89.0 bits (211), Expect = 1e-15 Identities = 45/173 (26%), Positives = 80/173 (46%), Gaps = 1/173 (0%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ +++ G + + + PQP EW K ++ K T S L + K D Sbjct: 5872 KKLKVRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARRED 5931 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTII 1413 +G + + EN G ++ V ++DKP PP G E+ + ++++ W P++ G + + Sbjct: 5932 SGTFTITAENPYGKDSADIEVIVVDKPGPPIGPLTPTEVTAHTVSLSWKPPQDNGGAEVT 5991 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 YVVE TT S + K +++ L+ YRFR A N +S+ E Sbjct: 5992 GYVVERPTPTTTYERSCQGTAKPNFTVKGLEEGKKYRFRVRAENMYGVSEPLE 6044 Score = 84.6 bits (200), Expect = 3e-14 Identities = 95/391 (24%), Positives = 157/391 (40%), Gaps = 24/391 (6%) Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTS 1654 EG P P W +NG ++ IT++E + I ++ Y A+N AG + Sbjct: 6978 EGKPTPTARWLRNGREVTLGGR--ITSEESKGKFKLFISDMWEVDEGDYACVAANDAGQA 7035 Query: 1655 SVEVTLKVYDKP--SKPEGPVIMREISRESVTIEWKP--PLDDGGLELTKYAIEKHEPDN 1710 + +K+ + P ++ + + + E + I + PLD + L++ + E Sbjct: 7036 TSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFTGDLPLD---VTLSQNGLPVEESQR 7092 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 +K D + + + + ++ + + +N G ++ IV T VP Sbjct: 7093 ---LKFTVFDEFIIIFIREVVKQDAG-QYTLTVKNDSG---SVTGNFIVYITG--VPGAP 7143 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXA-RIQK 1828 I + W P +GG P+ Y VE K W + +Q Sbjct: 7144 TAPLDVTDISRHMCNLAWRPPVYDGGLPVTHYVVERKDITYANWITINSFCKDCSFTVQG 7203 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 L+ Y FR+ A NE G P T + I PPS P V+E V L+W + Sbjct: 7204 LTEGQEYLFRVMAVNENGMGPPLTGVNPIKAKAPYDPPSPPGTPNVTEVGGDFVHLEWDK 7263 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 P +GGS I Y +E + + WT + + + N+ E + FR+ AEN G+ Sbjct: 7264 PAHDGGSRIKGYWVEKREIGSNIWTMVNQYICLPTQINVSNLIEDRQYEFRVFAENDAGM 7323 Query: 1949 SLP-TESQSVRLEKHATVPSPPTAPLEIRMV 1978 S P T S SVR+ K +PP +R V Sbjct: 7324 SEPSTCSTSVRI-KDPNAATPPEIITPLRNV 7353 Score = 76.2 bits (179), Expect = 9e-12 Identities = 109/425 (25%), Positives = 165/425 (38%), Gaps = 47/425 (11%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKK-CKHT-KPSIDSK---SASLTIKKVENTDAG 1356 G+ V A PQP W K +++ +H K D K L + KV N D G Sbjct: 247 GTSVIFSCRCVANPQPTIVWEFKGKKLREGARHRMKLEPDGKLYYMVILEVNKVTNADEG 306 Query: 1357 IYKLRLENNCGHADVEMNV-----TILDKP------SP--PGKPNILEIDSSSINICW-- 1401 Y+ N G +N+ T DKP +P P KP I + + C Sbjct: 307 EYRAVASNKLGEGVATINLHFEGKTASDKPKIPDGKAPRFPKKPEIRQEGDKLVMECILE 366 Query: 1402 --DEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 EPE T T I + E I + I K+ +I + + ++R A N Sbjct: 367 ANPEPEVTWFKGTEI--IQEQGRISMYKKICGKDQFIVSVTIMKPEASDGGQWRCNAFNP 424 Query: 1459 VDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 S+A+ + K + +PT ++KP I E I + PQP V W++ Sbjct: 425 FGDSNANIALNFEKGKAIPEGFAPTFLDKP-SIIPNESGTMITMKVRCKAKPQPTVEWFK 483 Query: 1518 DGKKLKTAK--------ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 DGKKL+ AK T E YKC+A N GE + + I+ Sbjct: 484 DGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFGEATANVNLNIE 543 Query: 1569 QKPVIT------ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 P T + IK + K G L+ A++ P P W K+G +L+ + Sbjct: 544 SDPEPTGQAPVFVEKPTIKFEEKAG-RVLMEALVRADPKPTSRWTKDGKELDVARVTATV 602 Query: 1623 TKEKTSVIRIK-ELKR---SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 TKEK + RI+ EL++ + Y N G + + L + P+ P I+ Sbjct: 603 TKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTIKRPPRIVSVF 662 Query: 1679 SRESV 1683 +R+ V Sbjct: 663 NRKVV 667 Score = 76.2 bits (179), Expect = 9e-12 Identities = 47/156 (30%), Positives = 78/156 (50%), Gaps = 8/156 (5%) Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDK-----PSPPGKPN 1388 K S +S + +E + ++++R EN G +D +E I K P PPG+PN Sbjct: 6699 KVSAFVRSCHYDVMGLEPNRSYMFRVRAENQYGLSDPLETLDPITAKFPFTVPDPPGRPN 6758 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTN 1446 IL+ D +S+ + WD P + G S I Y VEY+++ T W + + + +T ++ +L N Sbjct: 6759 ILDHDINSVVLTWDRPASDGGSKIQGYKVEYRDVTDTNWAAANDFLVKETTYTVHSLLIN 6818 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 Y FR A N S S ++ K+ + + SP Sbjct: 6819 HEYEFRVKAKNAAGFSKYSPPSKKIKMKGKYSVPSP 6854 Score = 74.9 bits (176), Expect = 2e-11 Identities = 50/176 (28%), Positives = 86/176 (48%), Gaps = 7/176 (3%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLT 1346 PKI+ + RIK G + + VDY PQP+ W + K ++ + T +I++ S T Sbjct: 5564 PKILGPLYDVRIKAGQVLHVDVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHT 5623 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPE 1405 + + N D+G Y++R++N G + V +LD P P P + E+ ++S+ + W P Sbjct: 5624 VNTMRN-DSGEYRIRVKNESGQDEATFQVIVLDTPGAPEGPLVYEEVQANSVVMSWKPPV 5682 Query: 1406 NTGNSTIIYYVVEYQEID-TTEWISVKNIT---KTQTSIQNLKTNSSYRFRAYAVN 1457 + G S I YV+E ++I W+ N + ++ L + Y R A N Sbjct: 5683 DDGGSPITGYVIEKRDISHGGGWVPAVNWVDPKQNHATVPRLLEGTQYDSRVRAEN 5738 Score = 72.1 bits (169), Expect = 2e-10 Identities = 58/216 (26%), Positives = 94/216 (43%), Gaps = 21/216 (9%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS-----------WTK 1914 PS P N VSE S S + + P+ +GG P+T YIIE + K+ W + Sbjct: 1764 PSPPTNVEVSEIFSTSCLITFGPPKDDGGLPLTYYIIERQDFSVKASHPRIWERTGGWAQ 1823 Query: 1915 IVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973 + + E+++ K + F+++ N +G S P V L K + Sbjct: 1824 VAEIPADEPLRFKSEDLENKKQYKFKVTVSNKLGPSDPFIHPKVILAKDPWDEPGKILHV 1883 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR--------DVTK-TMWMEVGKVDVNTL 2024 E+ G + W PE DGGAP+ GY I R +V + + W + ++ + Sbjct: 1884 EVNDWGPDHADLRWSRPETDGGAPITGYVIEFRTRAMPGAGEVDRFSDWAKGIEIQGDVT 1943 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + I DL E + Y R+ A N+ G EP + +P + Sbjct: 1944 EGTIPDLKEGNQYEFRVRAVNKAGPGEPSDPTKPIQ 1979 Score = 66.5 bits (155), Expect = 8e-09 Identities = 58/250 (23%), Positives = 107/250 (42%), Gaps = 39/250 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P + LR + CQ+ G PRP I+WF+ + S + M D D TL Sbjct: 7344 PEIITPLRNVMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTY-TLT 7402 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXXXXXADI 628 + +V+ ED + C A+N+ G S+ ++ ++ AP + Sbjct: 7403 VHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKIN---------------------- 7440 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 +PP F + D+G + +++ + P P I W +GE I + SV + Sbjct: 7441 ---VPPRFR---DTAFFDKGENAVIKIPFIGNPRPRITWQREGETIESGGHYSVETQ-QR 7493 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 H ++L + +V G Y + A N G S +++KI+ ++ P + ++S++ Sbjct: 7494 H---AILHLRDVTNLDTGNYRLTAENELGSDS--VIIKIQISDRPDPPRLPKVESIL--- 7545 Query: 749 GESVILSAQV 758 G +L+ Q+ Sbjct: 7546 GTECVLTWQI 7555 Score = 66.1 bits (154), Expect = 1e-08 Identities = 59/215 (27%), Positives = 98/215 (45%), Gaps = 23/215 (10%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-------ALPTKS 782 G+ P + K G +I ++ +P+P+I W + + PVK + Sbjct: 2 GDNFAPSFTQKPKLRQEDDGNKLIFDCKLSASPQPSIEWFREDTPVKESSRVKITVKPGK 61 Query: 783 DGDTHSI-TILKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAEPPLFI 836 G+ H + IL + +D G+Y +KA+N G E SA I + E+P + L Sbjct: 62 GGNIHDVQLILDDVEEEDAGLYKVKAKNKYG--EVSASINLNFSPNEQPVDIKQIDGLAP 119 Query: 837 NRFQEITVK-EKG--TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGEN--IE 889 Q+ +K E+G IK R+ +P P+ITW+R+ + S +T D ++ + Sbjct: 120 TFAQKPVIKQEEGGKHIKFECRILADPRPTITWFRDGLKVQESARCKVTTEKDEKSYFVT 179 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + TNV E D+G YK A N G+S+ + D Sbjct: 180 MAFTNVTVE-DAGKYKVTAKNELGESNATISLNFD 213 Score = 59.7 bits (138), Expect = 9e-07 Identities = 92/440 (20%), Positives = 163/440 (37%), Gaps = 42/440 (9%) Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 T KL E E P R I+ LL P P +W S+ + K +++ Sbjct: 8120 TYKLWQEEGEGAPSFTFLLRPRVIQCHQTCKLLCCLAGKPVPTVKWYKGSQELSKFDYSQ 8179 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD--------KPSPPGKP 1387 D ++ I + D+G Y+ N+ G + V + D K PP Sbjct: 8180 SHADGV-VTIEIVNCKPADSGKYRCVATNSLGTDETSCVVIVEDRRYIETTIKDLPPPPT 8238 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS--VKNITKTQTSIQNLKT 1445 + +D +S + + G S+ V T+ + K K Q+ T Sbjct: 8239 PAIRVDDTSSSSYFTSTHKDGRSSTSTKVEAASSSSTSSAAASGAKRTLKPYGKRQD-ST 8297 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCI 1504 S+ R R+ A E+++ ++ + P L K + + E + L C Sbjct: 8298 GSTSRSRS-ATKELELPP-----------DDSLMGPPGFSGELPKTLAIKDGEALCLKCT 8345 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P+P+V+W++DG+ L ++ + Y C A + G E Sbjct: 8346 VKGDPEPQVSWFKDGEPLSSSDIIDLKYRQGLASLTINEVFPEDEGLYVCKATSSLGSAE 8405 Query: 1561 TSCVVGI----QQ--------KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 T C + I QQ + I+ + Q+ G ++ I G +V+W Sbjct: 8406 TKCKLSISPMEQQINGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLH 8465 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 N +++ K++ T+ T +++I E+ + YT EA N G + TL V + Sbjct: 8466 NEKEIKPSKDFLYVTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEE 8525 Query: 1669 PEGPVIMREISRESVTIEWK 1688 + P ++ R +E K Sbjct: 8526 KKQPA-FKKFPRSQTVMEGK 8544 Score = 58.4 bits (135), Expect = 2e-06 Identities = 65/326 (19%), Positives = 131/326 (40%), Gaps = 35/326 (10%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDV--KKRTLI---IRKCTEDDQCEYTCVLL----DAKST 1276 +VTW+K +I++ + ++ + K + ++ I K D ++ C D+ + Sbjct: 372 EVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEASDGGQWRCNAFNPFGDSNAN 431 Query: 1277 TKLKVE----VVE-FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 L E + E F P +D + G+ +T+ V +A PQP EW + K ++ Sbjct: 432 IALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRCKAKPQPTVEWFKDGKKLEAA 491 Query: 1332 KHT-----KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 K K + + S +K DAG YK N G A +N+ I P P G+ Sbjct: 492 KRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFGEATANVNLNIESDPEPTGQ 551 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW------ISVKNITKTQTSI 1440 + ++ +I E ++ +V T+ W + V +T T T Sbjct: 552 APVF-VEKPTIKF-----EEKAGRVLMEALVRADPKPTSRWTKDGKELDVARVTATVTKE 605 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNE 1497 ++ R + + + E+ ++ + +PT+++P + I + N Sbjct: 606 KDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTIKRPPR-IVSVFNR 664 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK 1523 + + C+ +P +W++D K++ Sbjct: 665 KVVIECVVISTSKPACSWFKDSSKVR 690 Score = 58.4 bits (135), Expect = 2e-06 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 3/122 (2%) Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 VY + A ++++ + + E E P F+ Q V ++ L P Sbjct: 6925 VYAINAAGKSDPSQSAQPVKIREAAP--GEKPFFVKNLQNTAVALHKSVTLECEAEGKPT 6982 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P+ W RN ++ IT +L I+++ E+D GDY CVA+N AG+++ A V Sbjct: 6983 PTARWLRNGREVTLGGRITSEESKGKFKLFISDM-WEVDEGDYACVAANDAGQATSIAHV 7041 Query: 922 TI 923 I Sbjct: 7042 KI 7043 Score = 57.6 bits (133), Expect = 4e-06 Identities = 69/310 (22%), Positives = 130/310 (41%), Gaps = 21/310 (6%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PPEIIT L+N + AT ++ K + WFK E+ S + DG L Sbjct: 7343 PPEIITPLRNVMALQHRSATLTCQIAGKPRPNISWFKGMRELCNSAKYAMNRDGDTYTLT 7402 Query: 1165 IYDCDLDDAGEYSCEVGNS----KCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVE 1219 ++D +D EY C NS A ++++ P IN R + +A + + Sbjct: 7403 VHDVYGEDEDEYMCRAQNSGGIRSTKADISIKLAPKINVPPRFRDTAFFDKGENAVIKIP 7462 Query: 1220 -IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 I + +TW ++ IE +++ + + L +R T D Y + + Sbjct: 7463 FIGNPRPRITWQREGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELGSDS 7522 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 +K+++ + P D R +++ ++ +Q P + +N+ II+K + Sbjct: 7523 VIIKIQISDRP----DPPRLPKVESILGTECVLTWQ-IPLWDGGANINNYIIEKRELPME 7577 Query: 1337 S-IDSKSASLTIKKVENTDAG-IYKLRL--ENNCGHADVEMNVTILDKPSP---PGKPNI 1389 S I + LT +++ G Y+ R+ EN G +D ++++ P+P K + Sbjct: 7578 SWIRCSNTRLTTAQIKGLSPGHKYQFRVYAENVYGRSDPSAVTSVVETPAPLTKKPKKKV 7637 Query: 1390 LEIDSSSINI 1399 E+D + I Sbjct: 7638 YEVDETGKKI 7647 Score = 56.4 bits (130), Expect = 8e-06 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 15/185 (8%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L C++ P P+I+W FKG + + + A+ D Y L + +V E Y A Sbjct: 7363 LTCQIAGKPRPNISW-FKGMRELCN-SAKYAMNRDGDTY--TLTVHDVYGEDEDEYMCRA 7418 Query: 713 VNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 N G S + IK K PP+ + + +GE+ ++ +GNPRP ITW + Sbjct: 7419 QNSGGIRSTKADISIKLAPKINVPPRFRD---TAFFDKGENAVIKIPFIGNPRPRITWQR 7475 Query: 771 NNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + +++ S H+I L+ D G Y L AEN G S +I ++ + Sbjct: 7476 EGETIESGGHYSVETQQRHAILHLRDVTNLDTGNYRLTAENELG--SDSVIIKIQ--ISD 7531 Query: 829 NAEPP 833 +PP Sbjct: 7532 RPDPP 7536 Score = 55.6 bits (128), Expect = 1e-05 Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 13/183 (7%) Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIR 1072 + +P + L EV + L +I T DVVW + + IKP K+ + + G Sbjct: 8427 DKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHNEKEIKPSKD-FLYVTEGDTY 8485 Query: 1073 KLYIRNTSVHDEGEYSCILRDE------SCTAEVTVV---ELPPEIITRLQNQKVNKGNK 1123 L I D G Y+C ++ +CT V + + P ++Q V +G Sbjct: 8486 LLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEKKQPAFKKFPRSQTVMEGKS 8545 Query: 1124 ATFEIELTKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVG 1181 ATF ++ K V W KDG + + S + +GKK+ +I C D G+Y + Sbjct: 8546 ATFSVKFEKDPLKVSWIKDGKPVDESSPRFKFQQEGKKEFSYEIPSCLPTDVGQYVVKAT 8605 Query: 1182 NSK 1184 + K Sbjct: 8606 SKK 8608 Score = 53.2 bits (122), Expect = 8e-05 Identities = 67/316 (21%), Positives = 122/316 (38%), Gaps = 38/316 (12%) Query: 1120 KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQL--TIDGKKQ---KLKIYDCDLDDA 1173 +G+K E L + V WFK IQ I + I GK Q + I + D Sbjct: 355 EGDKLVMECILEANPEPEVTWFKGTEIIQEQGRISMYKKICGKDQFIVSVTIMKPEASDG 414 Query: 1174 GEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFI----LVPANTDAYLTVEI----- 1220 G++ C G+S L E+ P F+ ++P + +T+++ Sbjct: 415 GQWRCNAFNPFGDSNANIALNFEKGKAIPEGFAPTFLDKPSIIPNESGTMITMKVRCKAK 474 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC-----EYTCVLL---- 1271 P T++ W+K +E ++ + + C D C +Y CV + Sbjct: 475 PQPTVE--WFKDGKKLEAAKRLVIKGHKVTAEMFEYSCIVKDPCGADAGKYKCVAMNQFG 532 Query: 1272 DAKSTTKLKVEVVEFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 +A + L +E P P V+ ++ V + +A P+P W + K Sbjct: 533 EATANVNLNIESDPEPTGQAPVFVEKPTIKFEEKAGRVLMEALVRADPKPTSRWTKDGKE 592 Query: 1328 IKKCKHT----KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + T K D + ++K + TD G+YK ++N G + +N+ I P+ Sbjct: 593 LDVARVTATVTKEKDDLYRIRMELRKPQPTDGGVYKCNIKNEFGELNANLNLNIEVAPTI 652 Query: 1384 PGKPNILEIDSSSINI 1399 P I+ + + + I Sbjct: 653 KRPPRIVSVFNRKVVI 668 Score = 52.8 bits (121), Expect = 1e-04 Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 10/194 (5%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P F K + V + LEC P P WL G E+ + I S+ Sbjct: 6951 GEKPFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREV----TLGGRITSEESK 7006 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L I+++ + EG Y VA N G+A+ + +K G PP++ + ++ + +G+ Sbjct: 7007 GKFKLFISDMWEVDEGDYACVAANDAGQAT--SIAHVKIG--NPPRITQMQDALYLPEGD 7062 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAE 808 + + G+ +T +N PV+ + D I ++ +D G YTL + Sbjct: 7063 NTKIKIYFTGDLPLDVTLSQNGLPVEESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVK 7122 Query: 809 NSEGIAETSAVITV 822 N G + ++ + Sbjct: 7123 NDSGSVTGNFIVYI 7136 Score = 52.4 bits (120), Expect = 1e-04 Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 11/135 (8%) Query: 696 KITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQG 749 ++ ++ + + + V AVN G EASLPI K + K P++ L+ + VR+G Sbjct: 4046 RVNDLDEGETYEFRVRAVNEAGPSDPSEASLPITCKPR---KLAPKIDRRNLRDLTVREG 4102 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV-KDEGVYTLKA 807 E ++L +V+G P P + W KP+K + + ++ + + + K GV + A Sbjct: 4103 EPILLDVKVIGEPPPEVEWFHGKKPIKETKDLRVENVPYNTKYINDEPLRKHSGVTKIVA 4162 Query: 808 ENSEGIAETSAVITV 822 N G E ITV Sbjct: 4163 TNQHGRDEAEITITV 4177 Score = 50.4 bits (115), Expect = 5e-04 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 5/134 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 + N+ + QE + ++AVN+ G E S P I P+++ PL + ++ G+ + + Sbjct: 5524 VPNLTEGQEYEFRIIAVNKAGNSEPSEPSDAVICRPRHLAPKILGPLYDVRIKAGQVLHV 5583 Query: 755 SAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 +G P+P + W ++K + T + + HS+ D G Y ++ +N G Sbjct: 5584 DVDYIGEPQPDVFWFNDDKELQIDMRTTITAINNHSVLHTVNTMRNDSGEYRIRVKNESG 5643 Query: 813 IAE-TSAVITVEEP 825 E T VI ++ P Sbjct: 5644 QDEATFQVIVLDTP 5657 Score = 50.4 bits (115), Expect = 5e-04 Identities = 62/270 (22%), Positives = 104/270 (38%), Gaps = 20/270 (7%) Query: 1719 VDRDVETYCIQKLN----ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 ++RD +TY + + + EYM R AQN G I + ++VP Sbjct: 7392 MNRDGDTYTLTVHDVYGEDEDEYMCR--AQNSGGIRSTKADISIKLAPKINVPPRFRDTA 7449 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEGKKWKXXXXXXXXXARIQKLSIN 1832 +N + I + + + P I ++ E + + G + ++ ++ Sbjct: 7450 FFDKGENAVIKIPFIGNPR----PRITWQREGETIESGGHYSVETQQRHAILHLRDVTNL 7505 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 T +R+ A NE+G+ KI I PP P+ V L W P + Sbjct: 7506 DTGNYRLTAENELGSDSVII---KIQISDRPDPPRLPK---VESILGTECVLTWQIPLWD 7559 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 GG+ I NYIIE + + +SW + + + I+ + + FR+ AEN G S P+ Sbjct: 7560 GGANINNYIIEKRELPMESWIRCSNTRLTTAQ--IKGLSPGHKYQFRVYAENVYGRSDPS 7617 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 SV P E+ G I Sbjct: 7618 AVTSVVETPAPLTKKPKKKVYEVDETGKKI 7647 Score = 50.0 bits (114), Expect = 7e-04 Identities = 34/100 (34%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 502 TSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 T + ++M P I L P + G + F+ V G P P+ W IKPS + Y Sbjct: 4670 TVKPKNMPPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRY 4729 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +D N L + E +GT+T VA+NA G S+ E+IV Sbjct: 4730 NDYN-TKLRVTGATREQSGTYTIVAENANGKDSADVEVIV 4768 Score = 49.6 bits (113), Expect = 0.001 Identities = 39/152 (25%), Positives = 71/152 (46%), Gaps = 19/152 (12%) Query: 697 ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 IT +K+ ++ + V AVN+ G +++LP + K ++P +K ++++ G+ Sbjct: 3154 ITGLKEGEKYEFRVRAVNKAGLGEPSDSTLPHTARAKF--RKPRIDRTNVKDVVIKVGQQ 3211 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA-----------LPTKSDGDTHSITILKPKKVKDE 800 + V+G+P+PT TW +KP+ + L S G+ + I+K ++ K Sbjct: 3212 YLYDIDVIGDPKPTNTWTLKDKPLLSILGQEVVTKDQLRVDSSGNNTKLLIMKAQR-KMS 3270 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 G Y L A N G IT+ P + P Sbjct: 3271 GKYVLTATNEHGEDSVKIDITILGPPSKPKGP 3302 Score = 49.2 bits (112), Expect = 0.001 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 2/77 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T + E +VEG P P++TW Q A IK + +D++ T+VIR+ D G + Sbjct: 3512 GITFKNESKVEGEPDPKVTWSLQGAPIKNER--VTITSEDHLTTIVIRKAKRSDTGVYKI 3569 Query: 584 VAKNAAGFASSTTELIV 600 AKN +G + +LIV Sbjct: 3570 FAKNDSGTDEAELDLIV 3586 Score = 48.4 bits (110), Expect = 0.002 Identities = 56/263 (21%), Positives = 103/263 (39%), Gaps = 17/263 (6%) Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 ++PE D G I E S+ ++ +D ++ + + N+ + E + V A+N G Sbjct: 6873 SVPESDGGSRITGYMIEKRELGSIWMKCNDYNIVDTQYTVLNLTEGSEVEFRVYAINAAG 6932 Query: 718 -----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 +++ P+ ++ + E P ++ L++ V +SV L + G P PT W +N Sbjct: 6933 KSDPSQSAQPVKIR-EAAPGEKPFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNG 6991 Query: 773 KPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 + V T + + DEG Y A N G A + A + + Sbjct: 6992 REVTLGGRITSEESKGKFKLFISDMWEVDEGDYACVAANDAGQATSIAHVKI-------G 7044 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 PP + + E K+ T + +T +N + S+ + E I + Sbjct: 7045 NPPRITQMQDALYLPEGDNTKIKIYFTGDLPLDVTLSQNGLPVEESQRLKFTVFDEFIII 7104 Query: 891 VITNVDSEIDSGDYKCVASNSAG 913 I V + D+G Y N +G Sbjct: 7105 FIREVVKQ-DAGQYTLTVKNDSG 7126 Score = 48.0 bits (109), Expect = 0.003 Identities = 40/146 (27%), Positives = 72/146 (49%), Gaps = 13/146 (8%) Query: 697 ITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + ++ + +E + V+AVN+ G ++S P+V K + ++P + L+ +I++ Sbjct: 5230 VPDLTEGEEYQFRVIAVNKAGNSDPSDSSQPVVCKARF--EKPGIDTKDLEDLIIKVNTR 5287 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + + + G PRP ++W N PV + + ++ G + I ++ D G YTL E Sbjct: 5288 LNYTVPIRGAPRPKVSWTVNGSPVVESERVDLQTYGKQTILDIPFAQRT-DSGRYTLTLE 5346 Query: 809 NSEGIAETSAVITVEEPTEENAEPPL 834 N G + SA TV T AE PL Sbjct: 5347 NDLG--KVSASGTVTSLTSLTAEGPL 5370 Score = 47.6 bits (108), Expect = 0.004 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 3/129 (2%) Query: 797 VKDEGVYT--LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 +K+ VY+ +KA N GI E S +N +P + F+ +T+K + K Sbjct: 2259 LKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGRSHKWAV 2318 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P P +TW R ++S ++ I + E+ IT+ + D+G Y N G+ Sbjct: 2319 DYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRK-DAGLYTLKIENRNGQ 2377 Query: 915 SSHGARVTI 923 S + + Sbjct: 2378 DSETVELVV 2386 Score = 46.8 bits (106), Expect = 0.007 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 9/137 (6%) Query: 700 VKKFQEGT---YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVI 753 V +EGT + V A N+ G EAS P + + P++ KS+ ++ G S Sbjct: 2256 VPGLKEGTVYSFRVKAANKAGIGEASEPTDNHLCKHKNRKPRIDRTNFKSVTIKVGRSHK 2315 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + VG P P +TW + + + D H+ + KD G+YTLK EN Sbjct: 2316 WAVDYVGEPDPDVTWSRGENVLSNTDRIHIENTDHHTEISITDATRKDAGLYTLKIENRN 2375 Query: 812 G-IAETSAVITVEEPTE 827 G +ET ++ + +P++ Sbjct: 2376 GQDSETVELVVLGKPSK 2392 Score = 46.4 bits (105), Expect = 0.009 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 K + G ++ + + P P + W+ K +E V D NI + + D Y + + + Sbjct: 2612 KQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQE-VKDSNIEI-VNVD---YNTKFNMIDA 2666 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734 K+ Q GTY ++A NR+G+ + + + +G +P Sbjct: 2667 KRKQTGTYKIIATNRDGKDEAAVEIVVLSGPGKP 2700 Score = 46.0 bits (104), Expect = 0.011 Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 9/138 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREG-----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 ++IT+V+ E + VVA N+ G +AS ++ K + P + + +R G Sbjct: 3455 IRITDVEPDHEYLFRVVAENKAGPSEPSDASDSVICKPRF--LAPRIDRKSVGRKTIRSG 3512 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAE 808 + ++V G P P +TW P+K + H TI ++ K D GVY + A+ Sbjct: 3513 ITFKNESKVEGEPDPKVTWSLQGAPIKNERVTITSEDHLTTIVIRKAKRSDTGVYKIFAK 3572 Query: 809 NSEGIAETSA-VITVEEP 825 N G E +I + +P Sbjct: 3573 NDSGTDEAELDLIVIGKP 3590 Score = 46.0 bits (104), Expect = 0.011 Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 5/132 (3%) Query: 698 TNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVIL 754 TN+ + E + + AVNR G E S P I PP++ L+ + + G + Sbjct: 4343 TNLIEGMEYQFRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKY 4402 Query: 755 SAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + G P PT +W + ++A T ++ D +S +++ D G Y + A NS G Sbjct: 4403 DCDISGEPPPTASWTYEGRKLEASRHVTIANIDYNSKLVIRDTVRADSGEYVITATNSSG 4462 Query: 813 IAETSAVITVEE 824 + + +TV + Sbjct: 4463 KDQVTVRVTVTD 4474 Score = 46.0 bits (104), Expect = 0.011 Identities = 64/274 (23%), Positives = 103/274 (37%), Gaps = 29/274 (10%) Query: 1132 KGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS------ 1183 KGD V WFKDG + S+ I L L I + +D G Y C+ +S Sbjct: 8347 KGDPEPQVSWFKDGEPLSSSDIIDLKYRQGLASLTINEVFPEDEGLYVCKATSSLGSAET 8406 Query: 1184 KCTAILTVEEPSINFTL-------RLPEFIL---VPANTDAYLTVEIPDET-LDVTWYKK 1232 KC ++ E IN R+ + +L VP T L+ +I T DV W Sbjct: 8407 KCKLSISPMEQQINGKSGRGDKLPRITQHLLSQEVPDGTAHTLSCKIGGATKFDVVWLHN 8466 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKVEV---VE 1285 + I+ ++ F +++ L I + +D YTC + ST L V + + Sbjct: 8467 EKEIKPSKDFLYVTEGDTYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLTVIIPGEEK 8526 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC--KHTKPSIDSKSA 1343 P + R + G T V ++ P WI + K + + + K Sbjct: 8527 KQPAFKKFPRSQTVMEGKSATFSVKFEKDPL-KVSWIKDGKPVDESSPRFKFQQEGKKEF 8585 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 S I TD G Y ++ + G ++ + Sbjct: 8586 SYEIPSCLPTDVGQYVVKATSKKGDTTAAFSLNV 8619 Score = 45.2 bits (102), Expect = 0.020 Identities = 35/129 (27%), Positives = 54/129 (41%), Gaps = 3/129 (2%) Query: 475 MDENNYTQYLQKKLNEKIDKLP--VFEKPTSEEQSMAPIFVE-KLRPKHTPDGSTVQFEC 531 + E Q+ K +N+ P + T++ + +AP+ L G ++F+C Sbjct: 3754 LTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTNLENITVRAGQMIKFDC 3813 Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 V G P P+ TWF A Q ++D+ +VI GTF A N AG Sbjct: 3814 NVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADNTAGH 3873 Query: 592 ASSTTELIV 600 T E+IV Sbjct: 3874 DEVTIEVIV 3882 Score = 44.8 bits (101), Expect = 0.026 Identities = 40/148 (27%), Positives = 63/148 (42%), Gaps = 8/148 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752 ++ +K+ + VVAVN+ G + S P + P + E LK + R + V Sbjct: 2856 RVPGLKEGNTYQFRVVAVNKAGPGDPSDPTKPHLAKARFLKPLINREKLKKITTRASQKV 2915 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENS 810 L V G P P I W NK V+ P +T L + + G+Y + A+N Sbjct: 2916 FLEVDVKGEPPPEIWWTLKNKKVETGPNYVIQAEDYLTKFTLNDAERRHTGIYKIHAKND 2975 Query: 811 EGIAETS-AVITVEEPTEENAEPPLFIN 837 G E +I ++ P + E PL I+ Sbjct: 2976 SGSDEAELEIIVLDRPGK--PEGPLEIS 3001 Score = 44.4 bits (100), Expect = 0.035 Identities = 48/187 (25%), Positives = 81/187 (43%), Gaps = 19/187 (10%) Query: 699 NVKKFQEGTYTVVAVNREGEA--SLPI-VLKIKTGEKEPPQVIEPL--KSMIVRQGESVI 753 +V + ++ Y VVA N+ G + S P + K + P ++ L K + VR GE + Sbjct: 5824 SVNEGEQYQYRVVANNKMGPSNPSDPSQAITAKPMREAPKLYLDGLLGKKLKVRAGEPID 5883 Query: 754 LSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 + + G P+P W K K P K ++ D + + K ++ +D G +T+ AEN Sbjct: 5884 IKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDHCRLFVDKARR-EDSGTFTITAENP 5942 Query: 811 EGIAETS-AVITVEEPTEENAEPPLFINRFQEITV-------KEKGTIKLVARVTRNPVP 862 G VI V++P PL TV ++ G ++ V P P Sbjct: 5943 YGKDSADIEVIVVDKPGPPIG--PLTPTEVTAHTVSLSWKPPQDNGGAEVTGYVVERPTP 6000 Query: 863 SITWYRN 869 + T+ R+ Sbjct: 6001 TTTYERS 6007 Score = 44.0 bits (99), Expect = 0.046 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 833 PLFINRFQEITVKEKGTIKLV--ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P I+R I V+ K V V+ PVP W N + I PS ++ N +L Sbjct: 4677 PPKIDRTNLIPVRSKAGQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRYNDYNTKL 4736 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +T E SG Y VA N+ GK S V + Sbjct: 4737 RVTGATRE-QSGTYTIVAENANGKDSADVEVIV 4768 Score = 44.0 bits (99), Expect = 0.046 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLK-IKTGEKEPPQVIEPL--KSMIVRQGESV 752 ++ N+ + QE + V A+N G+ + IK P++ L + M V GE Sbjct: 6513 RVINLTEHQEYEFRVAAINAAGQGPWSDPSENIKCISFRAPKITSDLSIRDMTVIAGEEF 6572 Query: 753 ILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKAE 808 ++ + +P+P + W P + D +S + + K K D G YT+K Sbjct: 6573 TITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNKSAKRSDIGKYTIKLT 6632 Query: 809 NSEGIAETSAVITV 822 NSEG S + V Sbjct: 6633 NSEGADSGSCKVNV 6646 Score = 44.0 bits (99), Expect = 0.046 Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 6/171 (3%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ LQ+ V LE E + T W R+G + E +G KL+ Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRITSEESKGKF-KLF 7012 Query: 1076 IRNTSVHDEGEYSCILRDESCTA-EVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132 I + DEG+Y+C+ +++ A + V++ PP I + +G+ +I T Sbjct: 7013 ISDMWEVDEGDYACVAANDAGQATSIAHVKIGNPPRITQMQDALYLPEGDNTKIKIYFTG 7072 Query: 1133 GDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 L V ++G ++ S ++ T+ + + I + DAG+Y+ V N Sbjct: 7073 DLPLDVTLSQNGLPVEESQRLKFTVFDEFIIIFIREVVKQDAGQYTLTVKN 7123 Score = 43.6 bits (98), Expect = 0.061 Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 21/163 (12%) Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEW--LVTAVIEGIPPP-EVIWYKNGNKLENDKEYNI 1621 VG + PVI D++QK+ ++ + V+EGIPPP ++ ++K ++ + Y I Sbjct: 1153 VGKEGPPVIV----DVQQKYTAVEDQNGYIDLVVEGIPPPTKIKFFKGITEIIDGGRYKI 1208 Query: 1622 TTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 T+ +T+ I I++ K + Y + N G S E+ V D + R + Sbjct: 1209 HTEGETNTITLCIRKTKANDEGHYKVIVGNEHGEDSAEMDFYVSDASG-----MDFRAML 1263 Query: 1680 RESVTIEWKPPLDD---GGLELT----KYAIEKHEPDNNRWIK 1715 ++ +WK +D G L+ T K + K E W+K Sbjct: 1264 KKKKYAKWKKDNEDPDWGDLKETEKEVKPQLRKVERKQEMWVK 1306 Score = 42.3 bits (95), Expect = 0.14 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 3/122 (2%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + A N G E S P + +++T+ +K ++ P P Sbjct: 4353 FRITAVNRAGAGEPSDPSKTIIAKPRFLPPKIDRKNLRDVTISAGSMLKYDCDISGEPPP 4412 Query: 863 SITWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 + +W + S +T N D N +LVI + DSG+Y A+NS+GK RV Sbjct: 4413 TASWTYEGRKLEASRHVTIANID-YNSKLVIRDT-VRADSGEYVITATNSSGKDQVTVRV 4470 Query: 922 TI 923 T+ Sbjct: 4471 TV 4472 Score = 42.3 bits (95), Expect = 0.14 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 7/133 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEA--SLPIVL-KIKTGEKEPPQVIEPLKSMIVRQGESVI 753 + + + +E + V+AVN G + S P L KI+ +P + ++ VR GE Sbjct: 6218 VLGLTELEEYYFRVIAVNEVGPSAPSRPSALIKIEEQANKPRIDLSAVRDPPVRAGEDFS 6277 Query: 754 LSAQVVGNPRPTITWCKNNKPVK--ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAEN 809 + G P+PT TW +++ + A P + D + I+ + D G Y L+ +N Sbjct: 6278 IHVPYTGFPKPTSTWYHDDEDINIGADPRIHEKLTDDYCAMIVTNAQRSDTGPYKLRLQN 6337 Query: 810 SEGIAETSAVITV 822 G S + V Sbjct: 6338 PSGFDSVSLNVRV 6350 Score = 42.3 bits (95), Expect = 0.14 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+ L+ +V EC+ EG P P W R + + L Sbjct: 6954 PFFVKNLQNTAVALHKSVTLECEAEGKPTPTARWLRNGREVTLGGRITS-EESKGKFKLF 7012 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I +++ D G + CVA N AG A+S + + P Sbjct: 7013 ISDMWEVDEGDYACVAANDAGQATSIAHVKIGNP 7046 Score = 41.9 bits (94), Expect = 0.19 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 8/117 (6%) Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 +PP +K + GS + +C + P P +W ++G ++ ++++A D Sbjct: 4380 LPPKIDRKNLRDVTISAGSMLKYDCDISGEPPPTASWTYEGRKLEASRHVTIA-NID--- 4435 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 Y S L I + + G Y + A N G+ + + + + T + PP+ P+K VR Sbjct: 4436 YNSKLVIRDTVRADSGEYVITATNSSGKDQVTVRVTV-TDKPSPPE--GPIKVSDVR 4489 Score = 41.9 bits (94), Expect = 0.19 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + + + G P+P W ++ ++PS+ M D+ L + + ED+GTFT Sbjct: 5879 GEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSDH-CRLFVDKARREDSGTFTI 5937 Query: 584 VAKNAAGFASSTTELIV 600 A+N G S+ E+IV Sbjct: 5938 TAENPYGKDSADIEVIV 5954 Score = 41.1 bits (92), Expect = 0.33 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + + + P P+ WL ++I P ++ Y + L++T + Q GT Sbjct: 4693 GQSFVFDVNVSGEPVPEKKWLLNKKDIKPSSVTNIRYND----YNTKLRVTGATREQSGT 4748 Query: 708 YTVVAVNREGE--ASLPIVLKIKTGEKEPP 735 YT+VA N G+ A + +++ K G + P Sbjct: 4749 YTIVAENANGKDSADVEVIVLDKPGTPQGP 4778 Score = 40.7 bits (91), Expect = 0.43 Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 + LR GS ++++C + G P P +W + ++ S+ + D N + LVIR+ Sbjct: 4387 KNLRDVTISAGSMLKYDCDISGEPPPTASWTYEGRKLEASRHVTIANIDYN-SKLVIRDT 4445 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIV 600 D+G + A N++G T + V Sbjct: 4446 VRADSGEYVITATNSSGKDQVTVRVTV 4472 Score = 40.3 bits (90), Expect = 0.57 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 9/162 (5%) Query: 670 KGEEIVPDENISVAIESDMHMYCSV-----LKITNVKKFQEGTYTVVAVNREGEA--SLP 722 K ++ +PD ++ ++ D+ K+ +K E + VVAVN+ G + S P Sbjct: 2532 KKDKFMPDWEVAAELKQDVIQPLKPGTPVETKVGGLKHRAEYQFRVVAVNKAGNSPESEP 2591 Query: 723 IVLKIKTGEKEPPQVIEP-LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781 + + P++ LK ++ G +V + G P P++ W + VK + Sbjct: 2592 TDYHLVKHKALKPRIDRTHLKQTTIKAGRNVKFDINIEGEPPPSVQWVLKEQEVKDSNIE 2651 Query: 782 -SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + D ++ + K K G Y + A N +G E + I V Sbjct: 2652 IVNVDYNTKFNMIDAKRKQTGTYKIIATNRDGKDEAAVEIVV 2693 Score = 40.3 bits (90), Expect = 0.57 Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 7/136 (5%) Query: 708 YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRP 764 + VVA+N+ G E S P + + PP++ + + V+ G+++ L VVG P Sbjct: 4946 FRVVAINKAGPGEPSEPTKPHVARPKNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPA 5005 Query: 765 TITW-CKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 T W ++N P L ++ +I I K+ D G +TL A N G + IT Sbjct: 5006 TKQWRVRDNDLYPSDRLSIINEDYMTTIKITDCKR-SDSGAFTLNARNKNGEDTCTVNIT 5064 Query: 822 VEEPTEENAEPPLFIN 837 V + P F N Sbjct: 5065 VLDVPGAPEGPVKFSN 5080 Score = 39.5 bits (88), Expect = 0.99 Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 5/99 (5%) Query: 630 EGIPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +PP + V G ++ L +V P W + ++ P + +S+ E Sbjct: 4971 KNLPPRIDRNAMMDVKVKAGDNLNLPVPVVGEPPATKQWRVRDNDLYPSDRLSIINED-- 5028 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 Y + +KIT+ K+ G +T+ A N+ GE + + + + Sbjct: 5029 --YMTTIKITDCKRSDSGAFTLNARNKNGEDTCTVNITV 5065 Score = 39.5 bits (88), Expect = 0.99 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 3/89 (3%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + + +A P+P + W E++PD + ++S + V K + K+ G Sbjct: 6569 GEEFTITVPFIASPQPKVQWWIGPNEVIPDNRVQFHMDSSNNSTVFVNK--SAKRSDIGK 6626 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 YT+ N EG S + + PPQ Sbjct: 6627 YTIKLTNSEGADSGSCKVNV-VDRPSPPQ 6654 Score = 39.1 bits (87), Expect = 1.3 Identities = 48/205 (23%), Positives = 85/205 (41%), Gaps = 18/205 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F+K+ K++ V E S ++LEC V E ++ W + G+++ PD I + I D Sbjct: 1488 PFKFTKQLKSKTVTENSKVILECD-VDEAEAEVEWFYGGQKLTPDSKI-LKIMKDGKKRQ 1545 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 V K ++ G Y+ N + E + I+++ + K + L+ + + + Sbjct: 1546 LVFK--SISMDDAGNYS-CRTNAD-ETTCEIIVQYENKFK------KKLQDQMTYERQPA 1595 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 ++V +P + W N K V + G H + I+K EG N Sbjct: 1596 TFEVELV-DPNAPLQWFINGKEVTEGDNYEFQKKGGVHRL-IIKEAATAHEGEIKAVCGN 1653 Query: 810 SEGIAETSAVITVEEPTEENAEPPL 834 E + S V E+P E P+ Sbjct: 1654 LETACQLS-VGEGEKPPSIKPEEPI 1677 Score = 37.9 bits (84), Expect = 3.0 Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNC 1366 A PQP+ EW +K+ K ++ + L + VE DAG+YK++ +N Sbjct: 32 ASPQPSIEWFREDTPVKESSRVKITVKPGKGGNIHDVQLILDDVEEEDAGLYKVKAKNKY 91 Query: 1367 GHADVEMNVTILDKPSP 1383 G +N+ P Sbjct: 92 GEVSASINLNFSPNEQP 108 Score = 37.1 bits (82), Expect = 5.3 Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G I ++ L P+P W KG+++ P + S+ SD +C L + ++ Sbjct: 5876 VRAGEPIDIKIPLSGAPQPVCEWSKKGKKLEPSKRTSMETTSD---HCR-LFVDKARRED 5931 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735 GT+T+ A N G+ S I + I + PP Sbjct: 5932 SGTFTITAENPYGKDSADIEV-IVVDKPGPP 5961 Score = 36.7 bits (81), Expect = 7.0 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F ++L+ K + S V EC V+ ++ WF + P D LV + Sbjct: 1491 FTKQLKSKTVTENSKVILECDVDE-AEAEVEWFYGGQKLTPDSKILKIMKDGKKRQLVFK 1549 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + +DAG ++C NA +T E+IV+ Sbjct: 1550 SISMDDAGNYSC-RTNA---DETTCEIIVQ 1575 Score = 36.7 bits (81), Expect = 7.0 Identities = 36/137 (26%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEP--LKSMIVRQGESV 752 K+ ++ + + + V AVN+ G++ T + K VI+ L+++ VR G+ + Sbjct: 3750 KVNDLTEGETYQFRVKAVNKAGQSKPSDASDNFTAKAKFLAPVIDRTNLENITVRAGQMI 3809 Query: 753 ILSAQVVGNPRPTITWCKNN-KPVKALP-TKSDGDTHSITILKPKKVK-DEGVYTLKAEN 809 V G P P TW N + P K D + H I+ + G + +KA+N Sbjct: 3810 KFDCNVTGEPIPKKTWFINKARQDNDQPGIKIDEEDHRTKIVIASCTRAHNGTFVIKADN 3869 Query: 810 SEGIAE-TSAVITVEEP 825 + G E T VI +++P Sbjct: 3870 TAGHDEVTIEVIVLDKP 3886 >UniRef50_Q4RE89 Cluster: Chromosome undetermined SCAF15134, whole genome shotgun sequence; n=11; Euteleostomi|Rep: Chromosome undetermined SCAF15134, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 8402 Score = 244 bits (598), Expect = 2e-62 Identities = 179/686 (26%), Positives = 291/686 (42%), Gaps = 32/686 (4%) Query: 1287 PPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 PP+++ D + ++ G + + + ++ P P W + + D Sbjct: 2686 PPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQL 2745 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 S+ I + DAG Y L LEN+ G ++V +LD P P + +I S+ + W+ Sbjct: 2746 SIDI--CDKYDAGKYILTLENSAGTKSAFVSVKVLDTPGAPVNLTVKDIKRESVTLTWEP 2803 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 P G + I Y+VE +E + +V N TKT + +LK + Y FR A NE + Sbjct: 2804 PLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVG 2863 Query: 1463 DASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 +A+ET + K + K+ V K + + E + + I G + + + Sbjct: 2864 EAAETEDSVKTSEPPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEE 2923 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 TAK T E ++ AFN+ G + + TI + Sbjct: 2924 WTVATTAK-TCEG----TVTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATI-HP 2977 Query: 1579 DIKQKHKV-----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 K G+ + + G P P++ W K+G L+ N++ + ++ I IK Sbjct: 2978 AFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIYIK 3037 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 + + + KYTI A+N+ GT++ E+T+ + DKP P GPV + E+S VT+ W+PP Sbjct: 3038 DANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNYVTLSWEPPEYT 3097 Query: 1694 GGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 GG ++ Y +EK + W I A + R T + KL EY FRV A+N G S A Sbjct: 3098 GGCQINNYIVEKRDTTTTAWQIVSATIAR--TTIKVTKLKTGIEYQFRVSAENRYGKSPA 3155 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK- 1811 + S +V + P +++ + W NGGSP++ Y +E K++ Sbjct: 3156 IVSPAVVAQYPFTQP-VAPGTPTISAATKDTMTVEWKAPTNNGGSPVLGYHIERKEKNSL 3214 Query: 1812 KWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 W + +L Y+FR+YA N G S + PP P Sbjct: 3215 LWTKLNKLLIPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISESTVARDPCDPPGTP 3274 Query: 1870 RNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN 1929 E T VTL+WT P+ +GGS IT Y++E K W K + + Sbjct: 3275 E---AIEITRNHVTLQWTRPQYDGGSAITGYVVERKKHPDTRWMKASFTNIIDTQFTVTG 3331 Query: 1930 IKEKDEIIFRISAENTVGV-SLPTES 1954 + E FR+ A N + S P+ES Sbjct: 3332 LTEDCVYEFRVIARNAASICSRPSES 3357 Score = 241 bits (591), Expect = 1e-61 Identities = 170/665 (25%), Positives = 279/665 (41%), Gaps = 23/665 (3%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K GS T+ V ++ P P W N + S+++++ D+G Y Sbjct: 4862 VKDGSSFTMTVPFKGKPVPTVTW--NKPDVDLRVRAVIDTTDTFTSISLEQANREDSGKY 4919 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + L N G + +NV +LD P P + + ++ SS + WD PEN G + Y+V+ Sbjct: 4920 TVTLSNVAGTTSLALNVRVLDSPGAPARVEVKDVTKSSATVTWDTPENEGGGPVKNYLVD 4979 Query: 1419 YQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +E W + + T + NL+ Y FR NE +ET E K+ T Sbjct: 4980 IREASKKGWTRLTDTCHRLTYKVTNLQEGGVYYFRVTGENEYGTGLPAETKEGTKITGIT 5039 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIF----GG--VPQPKVTWYRDGK----KLKTAKA 1527 K+ P +T E + L + GG + V G+ K T K Sbjct: 5040 KMIEKPSPPPKLGVTDVTKESVTLAWVKPEQDGGSRITGYLVEALEKGQEKWVKCGTTKF 5099 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKH-K 1585 + F++ E+ + VV Q + P I + N + + Sbjct: 5100 IHFTVSGLRENAEYFFRVRAENHAGFSETKEMVNAVVVKDQFECPEINMKNFPHNTVYVR 5159 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G + G P P+V K+ +L++ +N + I ++E S +Y I Sbjct: 5160 AGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVAGDSGRYDI 5219 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 ASN++GTS + + V D+PS P+GPV + +++ +SV+++W P DGG +T Y I+K Sbjct: 5220 TASNSSGTSKSFLNIVVLDRPSAPQGPVELFDVTEDSVSLKWLAPAYDGGSPITNYIIQK 5279 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 E W+ V+ T I KL EY FR+ A+N G SE ++S P+ + Sbjct: 5280 RETTTANWMDVSSAVARC-TMKIMKLTTGLEYQFRIRAENKYGISEHIDSPPVSVNLPYT 5338 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA 1824 VP + E + + W + +GGS + Y +++K + W+ Sbjct: 5339 VPE-APSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVNKTVIRAT 5397 Query: 1825 RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + +IN Y+F++ A N G S+ D + P P N + + T +V Sbjct: 5398 HFKITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEP---PLNLRIIDITKNTV 5454 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 TL W +P +GGSPIT YIIE K W K + + + + + FR+ A Sbjct: 5455 TLSWEKPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQDETYEFRVMA 5514 Query: 1943 ENTVG 1947 N VG Sbjct: 5515 RNAVG 5519 Score = 233 bits (569), Expect = 5e-59 Identities = 180/706 (25%), Positives = 306/706 (43%), Gaps = 43/706 (6%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 D + ++ + + L V + P+P +W + + + + S L I V+ Sbjct: 3777 DLRKIVNVRATATLRLFVTIRGKPEPEVKWSKADGTLNE--RAQIEVTSSYTMLVIDNVD 3834 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G Y + LEN G +NV +LD PS P + ++ +S+++CW+ P G + Sbjct: 3835 RFDTGKYVVTLENLSGSKTAFVNVRVLDSPSAPTNLEVKDVKQNSVSLCWEPPLIDGGAK 3894 Query: 1412 IIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I +Y+VE +E + SV N + I +L+ Y FR AVNE+ + +T+ Sbjct: 3895 ISHYIVEKREQKRMAFTSVCTNCVRNSYIISDLQQGGRYYFRVLAVNELGVG-LPASTDQ 3953 Query: 1471 YKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVT--WYRDGKKL 1522 KV + K+ V + ++ E E+ + I + QPK W + + Sbjct: 3954 VKVSEPPLPPGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCE-V 4012 Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG------IQQKPVITIS 1576 K +AT + ++ IA ND G+ + ++ I +P+I + Sbjct: 4013 KALEATVDG--------LSTGEEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLL 4064 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 + K GD+ + +G P PEV W K+G L+ N+ T + +S I IK+ Sbjct: 4065 FDTYSVK--AGDDLKIDVPFKGRPQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDAT 4122 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 + + KY I +++ GT S + + + DKP P + + E+S + V++ W PP DGG Sbjct: 4123 KDDTGKYEITLTSSVGTKSAVIAVIILDKPGPPSN-IKVDEVSADFVSLSWDPPTYDGGC 4181 Query: 1697 ELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 ++ Y +EK + W I A V R + + +L + EY FR+ ++N G S A++S Sbjct: 4182 QINNYVVEKRDTTTTTWQIVSATVAR--TSIKVTRLTQGTEYQFRIASENRYGKSSAIDS 4239 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK 1814 P+V + + P + + W +GGSP+ Y +E K++ W Sbjct: 4240 VPVVAQYPFEPPGPPTNLHVAHA-SKYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWT 4298 Query: 1815 XXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 + + YQFR+YA N G + D + P PRN Sbjct: 4299 KVNRGLLTENQFKMTGTEEGLMYQFRVYAENIAGIGPCTKASDAVA---ARDPCEPPRNL 4355 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKE 1932 V+ T SV+L W +PE +GG IT +I+E K + W K + + E Sbjct: 4356 RVTNITRTSVSLFWDKPEYDGGVKITGFIVERKELPNGRWLKCNFTNLQDTYFDVTGLTE 4415 Query: 1933 KDEIIFRISAENTVG-VSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 + F + A+N+ +S P+ES K PPT LE ++ Sbjct: 4416 DVQYEFHVIAKNSAELLSAPSESTGPVTVKDDV--DPPTIILEDKL 4459 Score = 219 bits (536), Expect = 5e-55 Identities = 214/890 (24%), Positives = 360/890 (40%), Gaps = 40/890 (4%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTL 1244 TA V+ P + ++V A L + + + W+K +E++ + + Sbjct: 2289 TAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARAEI 2348 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFP-PKIVDYEREYRIKR 1301 + K L+++ D +YT VL + T + V+V++ P P + Sbjct: 2349 KNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSNVTEE 2408 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 ++ L +I+ + + T S D + + K+ + I+++ Sbjct: 2409 KCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVTKLLKGNEYIFRVM 2468 Query: 1362 LENNCGHAD-VEMNVTILDKPS-PPGKPNILEIDS---SSINICWDEPENTGNSTIIYYV 1416 N G + +E I+ P PPG P LEI + S+ +CW+ PE G STI+ Y+ Sbjct: 2469 AVNKYGVGEPLESVPVIMRNPFVPPGPPQELEITNITRDSMTVCWNRPETNGGSTIVGYI 2528 Query: 1417 VEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 +E ++ W + + +T + + L + Y FR A N + T +K Sbjct: 2529 IEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXXPT--FKPG 2586 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDI-ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 T + V+ +I+ + I + C G ++T + + + T N Sbjct: 2587 CPT--NAHVVDTRKDSISLSWHRPIYDGGCEIQGY-AVEITKADEEEWVICTPPTGVNAT 2643 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-----KPVITISNEDIKQ--KHKV 1586 + A N G E + V G+ + +P I + D+++ + Sbjct: 2644 KFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRA 2703 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + +G P PE+ W K +L + + T E S + I + + KY + Sbjct: 2704 GGSMRICIPFKGRPTPEIRWAKEDAELPG--KVQVETGEDYSQLSIDICDKYDAGKYILT 2761 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 N+AGT S V++KV D P P + +++I RESVT+ W+PPL DGG + Y +EK Sbjct: 2762 LENSAGTKSAFVSVKVLDTPGAPVN-LTVKDIKRESVTLTWEPPLIDGGARIKNYLVEKR 2820 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 E + V D +Y + L E Y FRV+A+N G EA E+E V KT+ Sbjct: 2821 ESTRKVYSNV-DNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVGEAAETEDSV-KTS--E 2876 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR 1825 P + + +W + +GGS I+ Y +E++ G ++W Sbjct: 2877 PPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEEWTVATTAKTCEGT 2936 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + LS Y FR+ A NE G S P +T P+ F + S LK Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTF-NTYSIQNGENLK 2995 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945 P P + + + +K + + S + I++ + D + I+A N+ Sbjct: 2996 IDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIY-IKDANKDDAGKYTITATNS 3054 Query: 1946 VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005 VG + E + L+K P PPT P++I V SN V SW PE+ GG + Y + Sbjct: 3055 VGTA-TEEITVIILDK----PGPPTGPVKIEEVSSNYVTLSWEPPEYTGGCQINNYIVEK 3109 Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 RD T T W V T + L Y R+ A N G S + S Sbjct: 3110 RDTTTTAWQIVSATIART-TIKVTKLKTGIEYQFRVSAENRYGKSPAIVS 3158 Score = 219 bits (535), Expect = 7e-55 Identities = 199/803 (24%), Positives = 339/803 (42%), Gaps = 56/803 (6%) Query: 1189 LTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFT 1243 + ++EP I T L L+ T++IP V W ++ +++T++ Sbjct: 7192 VVIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVIWKLEEMKLKETDRIL 7251 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302 + + ++ TL++R D +Y VL ++ V V V P E Sbjct: 7252 IRTTDERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVTVAVVGRPSPPTGPVEVSGVSS 7311 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYK 1359 TL A D + + I++K + S ++S TIK T Y Sbjct: 7312 ESCTLSWSEPADDGGTD---ITNYIVEKRESGSASWQVVNSSVKRTTIKVTHLTKYMEYT 7368 Query: 1360 LRL--ENNCGHA-DVEMNVTILDKP----SPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 R+ EN G + VE ++ P SPP +P+++ + +++I I WD P G S I Sbjct: 7369 FRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRPDVVSVSANAIGIKWDVPYADGGSKI 7428 Query: 1413 IYYVVEYQEIDTTEWISVKNIT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 Y +E +E +T W+ + + + NL Y+FR YA+N I+ S+ +E Sbjct: 7429 TGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQFRVYAMN---IAGLSKASEA 7485 Query: 1471 YKVIKETKIQSPTVEKPLKNIT--------TEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + I P + + +IT T P D + I G V + KV + Sbjct: 7486 SRPILALNPVDPPGKPEVTDITRSSASLCWTVPFNDGG-SKIVGYVVERKVYSADEWDDN 7544 Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYK--CIAFNDHG----EVETSCVVGIQQK---PVI 1573 + K Y Y+ IA N G E+S V + + P Sbjct: 7545 RWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGVHSAASESSGPVTCKDEYSPPRA 7604 Query: 1574 TISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 + ++ + + + G + ++ + G P P V W K LE ++Y++T ++ Sbjct: 7605 ELDSKLVGETVTISAGSDLVLDGAVGGKPEPTVYWSKGDKILELGEKYSLTYTATRAMAV 7664 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 IK RS + +Y + N +G + V LKV D P P +++ ++ E T+ WK PL Sbjct: 7665 IKNCDRSDTGRYCLTVKNASGVKTAWVNLKVLDTPGPPADKIVISRVTEEKCTVSWKIPL 7724 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 +DGG +T Y +E+ E W+ V + + + +L +N EY+FRV N G Sbjct: 7725 EDGGDSVTHYVVERRETSRLNWVLV-EAECKTLSCVSSRLIKNNEYIFRVRGVNKFGPGV 7783 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811 LESEP++ + A +PS + E V I W E +GGS I +Y V+ +++ Sbjct: 7784 PLESEPVIARNAYTIPS-QPGTPETTAVGKEHVIIEWLKPESDGGSEISNYIVDKREKSS 7842 Query: 1812 -KW---KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK---TLT 1864 +W ++ L + YQFR+ A N G S P + I T Sbjct: 7843 TRWTRVNKTYTIYDTRLKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPA 7902 Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 PPS PR ++++T S+++ WT P +GGS ++ Y++E + W + T +E Sbjct: 7903 PPSVPR---ITDTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNE 7959 Query: 1925 HCIENIKEKDEIIFRISAENTVG 1947 + + FR++A N+ G Sbjct: 7960 FVAAGLAANKKYRFRVAALNSKG 7982 Score = 213 bits (520), Expect = 4e-53 Identities = 193/769 (25%), Positives = 331/769 (43%), Gaps = 48/769 (6%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 +V+W K +++ T + +++ ++I+ T+DD +Y L + T + V+ Sbjct: 4089 EVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIAVI- 4147 Query: 1286 FPPKIVDYEREYRIKRGSDVTL-LVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSA 1343 I+D + +V+ V P D +N+ +++K T + SA Sbjct: 4148 ----ILDKPGPPSNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRDTTTTTWQIVSA 4203 Query: 1344 SL---TIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDK-P-SPPGKPNILEIDSSS 1396 ++ +IK T Y+ R+ EN G + +V ++ + P PPG P L + +S Sbjct: 4204 TVARTSIKVTRLTQGTEYQFRIASENRYGKSSAIDSVPVVAQYPFEPPGPPTNLHVAHAS 4263 Query: 1397 ---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451 + + W+ P + G S + Y +E +E ++ W V +T+ Q + + Y+F Sbjct: 4264 KYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWTKVNRGLLTENQFKMTGTEEGLMYQF 4323 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQ 1510 R YA N I+ T+ + P + NIT T + + GGV Sbjct: 4324 RVYAEN---IAGIGPCTKASDAVAARDPCEPPRNLRVTNITRTSVSLFWDKPEYDGGV-- 4378 Query: 1511 PKVTWYR-DGKKLKTA---KATYENRXXXXXXXXXXXXXXXYK--CIAFND----HGEVE 1560 K+T + + K+L K + N Y+ IA N E Sbjct: 4379 -KITGFIVERKELPNGRWLKCNFTNLQDTYFDVTGLTEDVQYEFHVIAKNSAELLSAPSE 4437 Query: 1561 TSCVVGIQQK--PVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 ++ V ++ P I + ++Q + G+ + A I G P P V W K+G ++E Sbjct: 4438 STGPVTVKDDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPVVSWSKDGKEIEAK 4497 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 IT+ + + +++ R S +Y + N AGT SV V KV D+P P GP+ + Sbjct: 4498 ARCEITSTNFNTTLIVRDAIRRDSGQYVLTLHNVAGTRSVAVNCKVLDRPGPPSGPLAIT 4557 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 ++ E ++ W PP ++GG E+ Y +EK E W V D T + KL + E Sbjct: 4558 GLTAEKCSLAWGPPQENGGAEIMHYIVEKRETSRLAWTLVYG-DMKATTCKVTKLLKGNE 4616 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y+FRV N G E LESEP VP+ + +E++ I W +GG Sbjct: 4617 YIFRVRGVNKYGDGEPLESEPTKAMDPFTVPT-PPTNVQVTAVTSEAMTICWERPVSDGG 4675 Query: 1797 SPIIDYKVEIKQE-GKKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTSLPYTS 1853 S I Y +E +++ G +W R++ L Y++R++A N G S P Sbjct: 4676 SSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRVFAENSAGLSAPSIP 4735 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 I PS P + +ST +VTL W +P +GG+P+T Y +E++ W Sbjct: 4736 CPLIKAEDPQFLPSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPVTGYRVEYRKTLDDEW- 4794 Query: 1914 KIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +V V + + E + + E +F I + N +GVS P+ ++ K Sbjct: 4795 -VVAVQNTKNTEFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDKQVAK 4842 Score = 212 bits (518), Expect = 8e-53 Identities = 174/695 (25%), Positives = 294/695 (42%), Gaps = 35/695 (5%) Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 V +Y + G DV + + + P PN W + + S ++ +L I KV Sbjct: 5943 VQMTTQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTERATTLVIPKV 6002 Query: 1351 ENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 D G Y L +EN G V +++ +LD PS K + + + + W+ P G Sbjct: 6003 TRDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLLVKNVSRGELTLSWEAPVIDGG 6062 Query: 1410 STIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 + Y+VE + + + T + L + +Y FR A NE + D ET+ Sbjct: 6063 CPVTNYIVEKKGSTMKAYQVITAECANTSYKVSGLDIDVAYFFRVSAENEYGVGDPCETS 6122 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLK--- 1523 ++ T+ P + + + +T+ + ++ T GG +T Y KK + Sbjct: 6123 G---PVRATETPGPVKDLVMLD-STKGSVTLQWTRPDHDGG---SHITDYIIEKKAQEEN 6175 Query: 1524 --TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV--VGIQQ---KPVITIS 1576 T AT + R ++ A N+ G + S + + +Q P +S Sbjct: 6176 SWTLAATCK-RCSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLS 6234 Query: 1577 N-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 + + + +VG + +G P P + W K+ L+ ++ T + + + ++ Sbjct: 6235 DYPNAELAVRVGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGA 6294 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 K+ H+ +YT+ N + ++ + PS P GP+ EI +S+ I W P +DGG Sbjct: 6295 KKEHAGQYTLVLDNRTIKNYFDINVITLGPPSVPVGPIRFDEIKAQSIIISWDEPKEDGG 6354 Query: 1696 LELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 E+T Y++EK E W V + V R T+ I L + +Y FRV A+N G S L Sbjct: 6355 GEITCYSVEKRETSQANWKMVCSSVVR--TTFKIPNLVKGTQYQFRVRAENKYGVSNPLT 6412 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW 1813 S +V + P + ++ + I W + +GGSPI+ Y VE K W Sbjct: 6413 SLDVVAQHQYK-PPGPPGKPVAYNVTSDGMTIRWEAPDFDGGSPIMGYHVEKKDRNSLMW 6471 Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + RI L Y FR+YA N G S P + K + ++P P Sbjct: 6472 QKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLS-PVSEQSKHAL--AISPVDPPGT 6528 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 V + T SVTL+W P+ +GGS I Y +E + +GK W + S + + + Sbjct: 6529 PVCIDVTRDSVTLQWDTPKKDGGSKIVGYSVERRQGRGK-WLRCNFTDVSETQFTVTALS 6587 Query: 1932 EKDEIIFRISAENTVG-VSLPTESQSVRLEKHATV 1965 D FR+ A N VG +S P+ S + K ++ Sbjct: 6588 PGDRFEFRVIARNAVGTISPPSNSSGYIMTKDESI 6622 Score = 207 bits (506), Expect = 2e-51 Identities = 189/722 (26%), Positives = 306/722 (42%), Gaps = 61/722 (8%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PG P+ + +SI +CW P + G + I Y++E +E + W+ V + IT+ + Sbjct: 6784 PDAPGTPDATHVTGNSITMCWTRPRSDGGNEIKQYILERREKKSLRWVKVSSKRAITELR 6843 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITTEPN 1496 + NL + Y FR A N + AS T+ +K + T S PTV K + + T+ + Sbjct: 6844 HRVTNLTEGNEYEFRVMAENGAGVGPASSTSRLFKCREPTSAPSAPTVIKVIDS--TKSS 6901 Query: 1497 EDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYEN-----RXXXXXXXXXXXXXXXYKC 1550 IE T +F G + + + D K + N ++ Sbjct: 6902 VTIEWTKPVFDGGMEI-IGYNIDMCKASLEEWHRVNSQICIHTRYTAKGLVPGELYKFRV 6960 Query: 1551 IAFNDHGEVETSCVVG-IQQKPVITISNEDI----KQKHKVGDEWLVTAVI--EGIPPPE 1603 A N GE E S + +Q +T DI KQ H V + VT + G P P Sbjct: 6961 SAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFKQTHTVKNGGTVTLQVAFRGKPAPL 7020 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 W K +L + N T T + I+ R + KYT+ N +G S+ T+KV Sbjct: 7021 ATWSKADGELPIMADVNTTNTSST--LTIEGCTRYEAGKYTLSLENNSGRKSITFTIKVL 7078 Query: 1664 DKPSKPEGPVIMREISRESVTIE---------------------WKPPLDDGGLELTKYA 1702 D P P GP+ ++++ + E W P DGG + Y Sbjct: 7079 DTPGPP-GPIAFKDMTEPIIATEEPAPPKRLDVIDTTSSTASLVWLKPEHDGGSRIRGYV 7137 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761 +E +++W+ + + ++ ++ L EN EY FRV A+N G SE + +VIK Sbjct: 7138 VEYRAKGSDQWLLSGET-KSLKML-VEGLIENREYDFRVKAKNDAGISEPQGTFGSVVIK 7195 Query: 1762 TALDVPSXXXXXXXXXXIDNE--SVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX 1818 P+ I + + + P +I E+K +E + Sbjct: 7196 EPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVIWKLEEMKLKETDRILIRTT 7255 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 ++ + + ++ + N G +T + +G+ +PP+ P VS + Sbjct: 7256 DERTTLLVRDSKRSDSGKYYLVLENSAGVKT-FTVTVAV-VGRP-SPPTGPVE--VSGVS 7310 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEI 1936 S S TL W+EP +GG+ ITNYI+E + SW V SV I+ ++ + E Sbjct: 7311 SESCTLSWSEPADDGGTDITNYIVEKRESGSASWQ---VVNSSVKRTTIKVTHLTKYMEY 7367 Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996 FR+ AEN GVS ES V ++ PSPPT P ++ V +N + W P DGG+ Sbjct: 7368 TFRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRP-DVVSVSANAIGIKWDVPYADGGS 7426 Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 + GY I ++ +W+ K+ + + +L E Y R+YA N GLS+ E+ Sbjct: 7427 KITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQFRVYAMNIAGLSKASEAS 7486 Query: 2057 EP 2058 P Sbjct: 7487 RP 7488 Score = 198 bits (482), Expect = 2e-48 Identities = 174/664 (26%), Positives = 289/664 (43%), Gaps = 57/664 (8%) Query: 1323 VNSKIIKKCKHTKPS---IDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HAD---V 1371 + + II+K + T + + S A T+K ++ T Y+ R+ EN G H D V Sbjct: 5272 ITNYIIQKRETTTANWMDVSSAVARCTMKIMKLTTGLEYQFRIRAENKYGISEHIDSPPV 5331 Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 +N+ P P P I + I + W EP++ G S + Y ++ ++ ++ W V Sbjct: 5332 SVNLPYT-VPEAPSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVN 5390 Query: 1432 N--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK--ETKIQSPTVEKP 1487 I T I N+ Y F+ A N +S S+ ++ I E + ++ Sbjct: 5391 KTVIRATHFKITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEPPLNLRIIDIT 5450 Query: 1488 LKNITT---EPNEDIELTCIFGGVPQPKVTWY----RDGKKLKTAKATYENRXXXXXXXX 1540 +T +PN D GG P +T Y ++G + KA N Sbjct: 5451 KNTVTLSWEKPNYD-------GGSP---ITGYIIEKKEGSSSRWFKANLTNVTDTRFTVT 5500 Query: 1541 XXXXXXXY--KCIAFNDHGEVET-SCVVG------IQQKPVITISNEDIKQ-KHKVGDEW 1590 Y + +A N G + S + G P I I E + + K + + Sbjct: 5501 GLNQDETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQEYLSEVKFRAESDV 5560 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASN 1649 + I P P + W+K+G +L+ + + T E TSV +++ R +S Y ++ N Sbjct: 5561 ELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFESTSVF-LRDTTRLNSGSYEVKVKN 5619 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 + G++ V L + DKP P G + ++++ +++TI W PP D+GG +T Y +EK E Sbjct: 5620 SLGSACATVKLLIQDKPGPPAGEIQFKKVTADNITIMWSPPADEGGAMVTHYIVEKRETS 5679 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 W V++ D + +L + EY+FRV N G + LESEP++ K A VP Sbjct: 5680 RVMWSIVSEKLVDC-IVNVPRLIQGNEYIFRVRGVNKYGIGDPLESEPVIAKNAF-VPPS 5737 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK--KWKXXXXXXXXXAR-- 1825 I ++ + W +GGS I Y +E K+E K +W R Sbjct: 5738 EPSKPKVTMITKSTMTVIWERPALDGGSDIDGYYLE-KREKKSLQWFKVVKGTIRDTRQK 5796 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + L N YQFR+ A N+ G + D + P +P V +ST S+TL Sbjct: 5797 VSNLVENNEYQFRVCAVNKAGAGNYSEASDLYRAYDPIDLPGEPSKLRVVDSTKSSITLG 5856 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAE 1943 W +P +GGS IT+Y+++ + + W VT+ V E+ + ++K F++SA Sbjct: 5857 WEKPIYDGGSEITHYVLDQMNTEEREW---VTINPQVKACEYVVSHLKPGTYYFFKVSAV 5913 Query: 1944 NTVG 1947 N G Sbjct: 5914 NCKG 5917 Score = 196 bits (479), Expect = 4e-48 Identities = 176/703 (25%), Positives = 298/703 (42%), Gaps = 60/703 (8%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTS 1439 PSPP KP I++ +++ + W++P G + + Y VEY++ EW ++V+N T+ + Sbjct: 4748 PSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPVTGYRVEYRKTLDDEWVVAVQNTKNTEFT 4807 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPN 1496 + L + Y F ++N++ +S+ S ++ K + + + + P E + K + + Sbjct: 4808 VVKLTPGAEYVFVIKSINKIGVSEPSPESD--KQVAKEREEEPVFEISNEMRKTLIVKDG 4865 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFN 1554 +T F G P P VTW + L+ T + Y N Sbjct: 4866 SSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTSISLEQANREDSGKYTVTLSN 4925 Query: 1555 DHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 G + V + P + +D+ K W T EG P V Y + Sbjct: 4926 VAGTTSLALNVRVLDSPGAPARVEVKDV-TKSSATVTW-DTPENEGGGP--VKNYLVDIR 4981 Query: 1613 LENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-------SSVEVT--LKV 1662 + K + +T ++ L+ + + N GT ++T K+ Sbjct: 4982 EASKKGWTRLTDTCHRLTYKVTNLQEGGVYYFRVTGENEYGTGLPAETKEGTKITGITKM 5041 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 +KPS P + + ++++ESVT+ W P DGG +T Y +E E +W+K Sbjct: 5042 IEKPSPPP-KLGVTDVTKESVTLAWVKPEQDGGSRITGYLVEALEKGQEKWVKCGTT--K 5098 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDN 1781 + + L EN EY FRV A+N GFSE E +V+K + P + Sbjct: 5099 FIHFTVSGLRENAEYFFRVRAENHAGFSETKEMVNAVVVKDQFECPE-----INMKNFPH 5153 Query: 1782 ESVYITWFPSEKNG----GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR------IQKLSI 1831 +VY+ + K G P+ KV + ++ + K +++ Sbjct: 5154 NTVYVRAGSTLKCEIPLMGRPL--PKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVA 5211 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPE 1890 + ++ I A N GTS + + I + L PS P+ V + + T SV+LKW P Sbjct: 5212 GDSGRYDITASNSSGTSKSFLN---IVV---LDRPSAPQGPVELFDVTEDSVSLKWLAPA 5265 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD---EIIFRISAENTVG 1947 +GGSPITNYII+ + +W + S C I + E FRI AEN G Sbjct: 5266 YDGGSPITNYIIQKRETTTANWMDV----SSAVARCTMKIMKLTTGLEYQFRIRAENKYG 5321 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 +S +S V + TVP P+ P EI V + +W P+ DGG+ + GY++ ++D Sbjct: 5322 ISEHIDSPPVSVNLPYTVPEAPSTP-EITAVTRECITVAWKEPKSDGGSHVFGYHLQMKD 5380 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 +W V K + F I +++ Y ++ A N G+S Sbjct: 5381 KNSILWQRVNKTVIRATHFKITNINAGLIYEFKVAAENAAGVS 5423 Score = 195 bits (475), Expect = 1e-47 Identities = 108/367 (29%), Positives = 176/367 (47%), Gaps = 7/367 (1%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G+ +++ A G P PEVIW K+G +++ + T +++ +K+ R + + Sbjct: 3387 GETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGGHFVL 3446 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 + N G V VT+KV D+P P+GP+ ++ ++ E + W P DGG ++ Y IEK Sbjct: 3447 KLVNVGGVKMVPVTVKVLDRPGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISHYIIEK 3506 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 E W V + + +Y I KL EY+FRV A N G E LESEP++ + Sbjct: 3507 RETSRLSWTMVEPKIQAI-SYKITKLLPGNEYIFRVTAVNKYGVGEPLESEPVIARNPFT 3565 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXX 1822 PS I +S+ +TW E NGG+ I Y +E + ++G +W Sbjct: 3566 TPS-APSTPEASAITRDSIVLTWERPESNGGADIEGYILEKRDKDGVRWTKCNKKRLNDL 3624 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 R+ L+ +Y+F++ A N G P + I + + PP P N V++ +S +V Sbjct: 3625 RFRVTGLTEGHSYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNPKVTDHSSTTV 3684 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRIS 1941 +L W+ P +GG+ IT Y++E K W G + + ++E E FRI Sbjct: 3685 SLSWSRPIYDGGANITGYVVEMKEAADDEWVICTPPTGVQATHYTVRKLRENAEYSFRIC 3744 Query: 1942 AENTVGV 1948 A N G+ Sbjct: 3745 AVNYEGL 3751 Score = 191 bits (466), Expect = 2e-46 Identities = 172/709 (24%), Positives = 293/709 (41%), Gaps = 56/709 (7%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT- 1436 +D P P K +++ SSI + W++P G S I +YV++ + EW+++ K Sbjct: 5834 IDLPGEPSKLRVVDSTKSSITLGWEKPIYDGGSEITHYVLDQMNTEEREWVTINPQVKAC 5893 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLK---NIT 1492 + + +LK + Y F+ AVN E + Y+ ++ I + ++ ++ T Sbjct: 5894 EYVVSHLKPGTYYFFKVSAVN---CKGKGEDIKMYQPVQAKDILEEADLDLDVQMTTQYT 5950 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 D+E+ G P P VTW R + + +NR + Sbjct: 5951 ARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAA-----DNRYTISSTERATTLVIPK--VT 6003 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIK-----QKHKVGD--------EWLVTAVIEGI 1599 +D G+ G+ + ++T+S + + QK V + W + G Sbjct: 6004 RDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLLVKNVSRGELTLSWEAPVIDGGC 6063 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P I K G+ + K Y + T E + ++ L + + + A N G Sbjct: 6064 PVTNYIVEKKGSTM---KAYQVITAECANTSYKVSGLDIDVAYFFRVSAENEYGVGDPCE 6120 Query: 1659 TLKVYDKPSKPEGPV---IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 T P GPV +M + ++ SVT++W P DGG +T Y IEK + N W Sbjct: 6121 TSGPVRATETP-GPVKDLVMLDSTKGSVTLQWTRPDHDGGSHITDYIIEKKAQEENSWTL 6179 Query: 1716 VADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 A R C + L EN FRV A+N G S+ + PI ++ + P Sbjct: 6180 AATCKR---CSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLSDY 6236 Query: 1775 XXXXID---NESVYITWFPSEKNGGSPIIDY-KVEIK-QEGKKWKXXXXXXXXXARIQKL 1829 + ++++I P K P+I + K + +E +K + ++ Sbjct: 6237 PNAELAVRVGQNIHIE-LPF-KGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGA 6294 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTE 1888 Q+ + N T Y + IT+G PPS P + E ++S+ + W E Sbjct: 6295 KKEHAGQYTLVLDNR--TIKNYFDINVITLG----PPSVPVGPIRFDEIKAQSIIISWDE 6348 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 P+ +GG IT Y +E + +W K+V I N+ + + FR+ AEN GV Sbjct: 6349 PKEDGGGEITCYSVEKRETSQANW-KMVCSSVVRTTFKIPNLVKGTQYQFRVRAENKYGV 6407 Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 S P S V + P PP P+ + + + W P++DGG+P++GY++ +D Sbjct: 6408 SNPLTSLDVVAQHQYKPPGPPGKPVAYNVTSDGMTI-RWEAPDFDGGSPIMGYHVEKKDR 6466 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 MW +V ++ ++ I L E Y R+YA N GLS E + Sbjct: 6467 NSLMWQKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLSPVSEQSK 6515 Score = 191 bits (465), Expect = 2e-46 Identities = 204/812 (25%), Positives = 324/812 (39%), Gaps = 64/812 (7%) Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 ++++ + +K G VTL V ++ P P W + + + S++LTI+ Sbjct: 6994 NFKQTHTVKNGGTVTLQVAFRGKPAPLATWSKADGELPIMADVNTT--NTSSTLTIEGCT 7051 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG---------------------KPNIL 1390 +AG Y L LENN G + + +LD P PPG + +++ Sbjct: 7052 RYEAGKYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEPAPPKRLDVI 7111 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 + SS+ ++ W +PE+ G S I YVVEY+ + +W+ + ++ L N Y Sbjct: 7112 DTTSSTASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVEGLIENREYD 7171 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGV 1508 FR A N+ IS+ T VIKE +I+ + N IT + + + G Sbjct: 7172 FRVKAKNDAGISEPQGTFGSV-VIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGR 7230 Query: 1509 PQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE---VET 1561 P PKV W + KLK T + R Y + N G T Sbjct: 7231 PAPKVIWKLEEMKLKETDRILIRTTDERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVT 7290 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 VVG P + + + W A G I K + + + N Sbjct: 7291 VAVVGRPSPPTGPVEVSGVSSE-SCTLSWSEPADDGGTDITNYIVEKRESGSASWQVVNS 7349 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKV----YDKPSKPEGPVIMR 1676 + K T I++ L + + + A N G S SVE T V + PS P P ++ Sbjct: 7350 SVKRTT--IKVTHLTKYMEYTFRVCAENKFGVSKSVESTPVVIKHPFVAPSPPTRPDVV- 7406 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 +S ++ I+W P DGG ++T Y IEK E + W++ + Y + L E E Sbjct: 7407 SVSANAIGIKWDVPYADGGSKITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLE 7466 Query: 1737 YMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y FRV A N G S+A E S PI+ +D P I S + W +G Sbjct: 7467 YQFRVYAMNIAGLSKASEASRPILALNPVDPPG----KPEVTDITRSSASLCWTVPFNDG 7522 Query: 1796 GSPIIDYKVEIK------QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGT 1847 GS I+ Y VE K + +W + LS TY++ + A+N G Sbjct: 7523 GSKIVGYVVERKVYSADEWDDNRWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGV 7582 Query: 1848 -SLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESNGGSP-ITNYIIEF 1904 S S +T +PP ++ + +V E+ + S + GG P T Y + Sbjct: 7583 HSAASESSGPVTCKDEYSPPRAELDSKLVGETVTISAGSDLVLDGAVGGKPEPTVYWSKG 7642 Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 + +T + I+N D + ++ +N GV ++ V L K Sbjct: 7643 DKILELGEKYSLTYTATRAMAVIKNCDRSDTGRYCLTVKNASGV----KTAWVNL-KVLD 7697 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024 P PP + I V SW P DGG + Y + R+ ++ W+ V + + TL Sbjct: 7698 TPGPPADKIVISRVTEEKCTVSWKIPLEDGGDSVTHYVVERRETSRLNWVLV-EAECKTL 7756 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 L +N+ Y+ R+ N+ G PLES+ Sbjct: 7757 SCVSSRLIKNNEYIFRVRGVNKFGPGVPLESE 7788 Score = 187 bits (455), Expect = 3e-45 Identities = 150/576 (26%), Positives = 240/576 (41%), Gaps = 34/576 (5%) Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W +P + G S I+ Y +E +E ++ W + I + L+ Y +R YA N Sbjct: 2117 WHKPPSDGGSAILGYHLERKEKNSILWTKINKTLIQDCRFKSTPLEEGIEYEYRVYAENI 2176 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT---CIFGGVPQPKVTW 1515 V I S+ +E + + P +P I T + + T G + V Sbjct: 2177 VGIGKCSKVSEI--CVAQDPCDPPG--RPEALIVTRHSVKLRWTPPQYDGGSLITGYVVE 2232 Query: 1516 YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVE--TSCVVGIQQKP 1571 RD + K KA++ N Y + IA N G + + I K Sbjct: 2233 KRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTGSITAKD 2292 Query: 1572 VITISNEDIKQKH------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 + + + K G+ + + A +EG P P W+K ++EN I + Sbjct: 2293 EVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARAEIKNTD 2352 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 +++ +K+ R +YT+ +N AGT SV ++KV D+P EGP+ + ++ E ++ Sbjct: 2353 FKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSNVTEEKCSL 2412 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 W PP DGG ++ Y I+K E W V+ D + + KL + EY+FRV+A N Sbjct: 2413 SWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSS-DCGATMFKVTKLLKGNEYIFRVMAVN 2471 Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G E LES P++++ VP I +S+ + W E NGGS I+ Y +E Sbjct: 2472 KYGVGEPLESVPVIMRNPF-VPPGPPQELEITNITRDSMTVCWNRPETNGGSTIVGYIIE 2530 Query: 1806 IK-QEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 + + G +W R+ L+ + Y+FR+ A N G K Sbjct: 2531 KRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXXPTFK------ 2584 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGS 1921 P P N V ++ S++L W P +GG I Y +E + W G + Sbjct: 2585 ---PGCPTNAHVVDTRKDSISLSWHRPIYDGGCEIQGYAVEITKADEEEWVICTPPTGVN 2641 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + I + E E RI A N +GV PTE V Sbjct: 2642 ATKFTITKLIEHQEYKVRICAINKLGVGEPTEVPGV 2677 Score = 186 bits (454), Expect = 4e-45 Identities = 117/389 (30%), Positives = 178/389 (45%), Gaps = 7/389 (1%) Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 A + G P P ++W K+G +LE+ + I T + +V+ K+ R +T+ ASN G Sbjct: 220 ANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPGGF 279 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 + +KV D+P P+ + + +++ E + W P DGG ++ + I+K E W Sbjct: 280 AKFTFNVKVLDRPGPPDS-LTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAW 338 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 VA D + KL + EY+FRV+A N G E LESEP++ VPS Sbjct: 339 TNVA-TDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVICTNPY-VPSDPPGQ 396 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQKLS 1830 I +S+ + W E +GGS I Y +E + + G +W R + L+ Sbjct: 397 PEVTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTVTDLRFKVSGLT 456 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 + Y+FR++A N G S P S T+ P P N V ++T S+TL W +P Sbjct: 457 LGHEYEFRVFAENNAGLSQPSLSSPFYKAEDTIFMPGPPGNPRVLDTTKSSITLSWNKPV 516 Query: 1891 SNGGSPITNYIIEFKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 +GGS IT YI+E + WT G + I N+KE E ISA N GV Sbjct: 517 YDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATSFTITNLKENQEYKINISATNCEGVG 576 Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 P + + +P E+R V Sbjct: 577 EPAAVPGIPKAEDRLLPPEIELGAELRKV 605 Score = 184 bits (447), Expect = 3e-44 Identities = 206/896 (22%), Positives = 359/896 (40%), Gaps = 53/896 (5%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249 +E P + L + I+V A + + T ++ W K+ + + + D Sbjct: 2684 IEPPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYS 2743 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 + ++ I C + D +Y L ++ T + V+V++ P V+ + IKR S VTL Sbjct: 2744 QLSIDI--CDKYDAGKYILTLENSAGTKSAFVSVKVLDTPGAPVNLTVK-DIKRES-VTL 2799 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKP---SIDSKSASLTIKKVENTDAGIYKLRL-- 1362 + P + + + +++K + T+ ++D+K + + + + +Y R+ Sbjct: 2800 TWEP---PLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLA 2856 Query: 1363 ENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 EN G A+ E +V + P GK + + ++ + W++P+ G S I+ Y +E Sbjct: 2857 ENEFGVGEAAETEDSVKTSEPPLSVGKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEM 2916 Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 Q + EW + ++ L T Y FR A NE SD K+ I Sbjct: 2917 QPAGSEEWTVATTAKTCEGTVTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPV-TAKDATI 2975 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXX-- 1536 P + + + E++++ G P PK+ W +DG+ LK T + N Sbjct: 2976 H-PAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKI 3034 Query: 1537 -XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLV 1592 Y A N G V I K P + E++ + V W Sbjct: 3035 YIKDANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNY-VTLSWEP 3093 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 G I K + + T T I++ +LK ++ + A N G Sbjct: 3094 PEYTGGCQINNYIVEKRDTTTTAWQIVSATIARTT--IKVTKLKTGIEYQFRVSAENRYG 3151 Query: 1653 TSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 S V+ V + +P P P I +++++T+EWK P ++GG + Y IE+ E Sbjct: 3152 KSPAIVSPAVVAQYPFTQPVAPGTPTI-SAATKDTMTVEWKAPTNNGGSPVLGYHIERKE 3210 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDV 1766 ++ W K+ + + +L E EY FRV A+N G SEA + SE V + D Sbjct: 3211 KNSLLWTKLNKLLIPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISESTVARDPCDP 3270 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR 1825 P I V + W + +GGS I Y VE K+ +W + Sbjct: 3271 PG----TPEAIEITRNHVTLQWTRPQYDGGSAITGYVVERKKHPDTRWMKASFTNIIDTQ 3326 Query: 1826 --IQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + L+ + Y+FR+ ARN S P S +IT + P + + T Sbjct: 3327 FTVTGLTEDCVYEFRVIARNAASICSRPSESTGEITAKDEIEAPEATMDSKFKDLTIVHA 3386 Query: 1883 TLKWTEPESNGGSPITN--YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 + G P+ ++ + K V + V + +++ D F + Sbjct: 3387 GETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGGHFVL 3446 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 N GV + + V L++ P PP PLE++ V + W P DGGA + Sbjct: 3447 KLVNVGGVKMVPVTVKV-LDR----PGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISH 3501 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 Y I R+ ++ W V + + + + I L + Y+ R+ A N+ G+ EPLES+ Sbjct: 3502 YIIEKRETSRLSWTMV-EPKIQAISYKITKLLPGNEYIFRVTAVNKYGVGEPLESE 3556 Score = 182 bits (442), Expect = 1e-43 Identities = 173/697 (24%), Positives = 288/697 (41%), Gaps = 39/697 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKT 1436 KP P ++++ SI++ W P G I Y VE + D EW+ + T Sbjct: 2584 KPGCPTNAHVVDTRKDSISLSWHRPIYDGGCEIQGYAVEITKADEEEWVICTPPTGVNAT 2643 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEP 1495 + +I L + Y+ R A+N++ + + +E K I + + ++ L K I Sbjct: 2644 KFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRA 2703 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + + F G P P++ W ++ +L K T E+ Y Sbjct: 2704 GGSMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQLSIDICDKYDAGKYILTLE 2763 Query: 1554 NDHGEVETSCVVGIQQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N G V + P + ++ +DIK++ V W +I+G + Y Sbjct: 2764 NSAGTKSAFVSVKVLDTPGAPVNLTVKDIKRE-SVTLTW-EPPLIDG--GARIKNYLVEK 2819 Query: 1612 KLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPS 1667 + K Y N+ K + R+ +LK + + A N G + E ++K + P Sbjct: 2820 RESTRKVYSNVDNKCTKTSYRVTDLKEGTLYYFRVLAENEFGVGEAAETEDSVKTSEPPL 2879 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 G V + +++ + + W+ P DGG + Y IE + W VA + E Sbjct: 2880 SV-GKVTLTNVTKTTASFSWEKPDYDGGSRILGYYIEMQPAGSEEWT-VATTAKTCEG-T 2936 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L+ EYMFRV A N G S+ + P+ K A P+ + E++ I Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKI 2996 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR------IQKLSINTTYQFRIY 1840 P G P D K+E K++G+ K + I+ + + ++ I Sbjct: 2997 D-IPVI---GCP--DPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTIT 3050 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N +GT+ T + + I PP+ P + E +S VTL W PE GG I NY Sbjct: 3051 ATNSVGTA---TEEITVIILDKPGPPTGPVK--IEEVSSNYVTLSWEPPEYTGGCQINNY 3105 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 I+E + +W +IV+ + + +K E FR+SAEN G S S +V + Sbjct: 3106 IVEKRDTTTTAW-QIVSATIARTTIKVTKLKTGIEYQFRVSAENRYGKSPAIVSPAVVAQ 3164 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 T P P P I + + W P +GG+P+LGY+I ++ +W ++ K+ Sbjct: 3165 YPFTQPVAPGTPT-ISAATKDTMTVEWKAPTNNGGSPVLGYHIERKEKNSLLWTKLNKLL 3223 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + F +L E Y R+YA N GLSE + E Sbjct: 3224 IPDTHFKTAELEEGIEYEFRVYAENMAGLSEASKISE 3260 Score = 182 bits (442), Expect = 1e-43 Identities = 161/683 (23%), Positives = 282/683 (41%), Gaps = 31/683 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKNITKTQ 1437 P PP P + + S+++++ W P G + I YVVE +E EW+ + T Sbjct: 3668 PGPPNNPKVTDHSSTTVSLSWSRPIYDGGANITGYVVEMKEAADDEWVICTPPTGVQATH 3727 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITTE 1494 +++ L+ N+ Y FR AVN + + + VI K+++P +E K + Sbjct: 3728 YTVRKLRENAEYSFRICAVNYEGLGEHVDLPG--SVIAAEKLEAPEIELDADLRKIVNVR 3785 Query: 1495 PNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + L G P+P+V W + DG + A+ + + Sbjct: 3786 ATATLRLFVTIRGKPEPEVKWSKADGTLNERAQIEVTSSYTMLVIDNVDRFDTGKYVVTL 3845 Query: 1554 NDHGEVETSCV-VGIQQKPVITISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 + +T+ V V + P + E D+KQ + V W + G I K Sbjct: 3846 ENLSGSKTAFVNVRVLDSPSAPTNLEVKDVKQ-NSVSLCWEPPLIDGGAKISHYIVEKRE 3904 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKP 1669 K T + S I I +L++ + + A N G T +V +P P Sbjct: 3905 QKRMAFTSV-CTNCVRNSYI-ISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSEPPLP 3962 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 G V + +++R +VT+ W+ P +DGG ++T Y +E +++W +V + +E + Sbjct: 3963 PGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCEV-KALEA-TVD 4020 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 L+ EY FRVIA N G S+A P+V+K P + + I Sbjct: 4021 GLSTGEEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLLFDTYSVKAGDDLKID- 4079 Query: 1789 FPSEKNGGSPIIDYKV--EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 P K P + +K ++ ++ + I+ + + T ++ I + +G Sbjct: 4080 VPF-KGRPQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVG 4138 Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 T + L P P N V E ++ V+L W P +GG I NY++E + Sbjct: 4139 TK------SAVIAVIILDKPGPPSNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRD 4192 Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 +W +IV+ + + + + E FRI++EN G S +S V + P Sbjct: 4193 TTTTTW-QIVSATVARTSIKVTRLTQGTEYQFRIASENRYGKSSAIDSVPVVAQYPFEPP 4251 Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 PPT L + ++ W P DGG+P+ GY+I ++ +W +V + + +F Sbjct: 4252 GPPT-NLHVAHASKYGMLVLWNRPASDGGSPVTGYHIECKEQNSLLWTKVNRGLLTENQF 4310 Query: 2027 NIRDLSENHTYMIRIYARNEIGL 2049 + E Y R+YA N G+ Sbjct: 4311 KMTGTEEGLMYQFRVYAENIAGI 4333 Score = 181 bits (441), Expect = 2e-43 Identities = 203/908 (22%), Positives = 362/908 (39%), Gaps = 71/908 (7%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKK------KSVIEDTEKFTL 1244 EEP + + + ++V + +TV + + VTW K ++VI+ T+ FT Sbjct: 4846 EEPVFEISNEMRKTLIVKDGSSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTS 4905 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRG 1302 IS + + +D +YT L + TT L V V++ P E + K Sbjct: 4906 IS--------LEQANREDSGKYTVTLSNVAGTTSLALNVRVLDSPGAPARVEVKDVTKSS 4957 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 + VT P ++V+ + K T+ + LT K + G+Y R+ Sbjct: 4958 ATVTWDTPENEGGGPVKNYLVDIREASKKGWTR--LTDTCHRLTYKVTNLQEGGVYYFRV 5015 Query: 1363 --ENNCGH---ADVEMNVTI------LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 EN G A+ + I ++KPSPP K + ++ S+ + W +PE G S Sbjct: 5016 TGENEYGTGLPAETKEGTKITGITKMIEKPSPPPKLGVTDVTKESVTLAWVKPEQDGGSR 5075 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 I Y+VE E +W+ ++ L+ N+ Y FR A N S+ E Sbjct: 5076 ITGYLVEALEKGQEKWVKCGTTKFIHFTVSGLRENAEYFFRVRAENHAGFSETKEMVN-- 5133 Query: 1472 KVIKETKIQSPTVEK---PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKA 1527 V+ + + + P + P + ++ G P PKV+ +D +LK T + Sbjct: 5134 AVVVKDQFECPEINMKNFPHNTVYVRAGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRF 5193 Query: 1528 TYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI--KQ 1582 E + Y A N G ++ + + +P ++ Sbjct: 5194 NAEVTPDSIKIILRESVAGDSGRYDITASNSSGTSKSFLNIVVLDRPSAPQGPVELFDVT 5253 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 + V +WL A G P I K N ++++ ++I +L + Sbjct: 5254 EDSVSLKWLAPAYDGGSPITNYIIQKRETTTAN--WMDVSSAVARCTMKIMKLTTGLEYQ 5311 Query: 1643 YTIEASNTAGTS----SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 + I A N G S S V++ + Y P P P I ++RE +T+ WK P DGG Sbjct: 5312 FRIRAENKYGISEHIDSPPVSVNLPYTVPEAPSTPEI-TAVTRECITVAWKEPKSDGGSH 5370 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756 + Y ++ + ++ W +V + I +N Y F+V A+N G S + S+ Sbjct: 5371 VFGYHLQMKDKNSILWQRVNKTVIRATHFKITNINAGLIYEFKVAAENAAGVSVFSKVSD 5430 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKX 1815 ++ A + P I +V ++W +GGSPI Y +E K+ +W Sbjct: 5431 AVLAIDACEPP----LNLRIIDITKNTVTLSWEKPNYDGGSPITGYIIEKKEGSSSRWFK 5486 Query: 1816 XXXXXXXXARIQKLSIN--TTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPP--SQPR 1870 R +N TY+FR+ ARN +G+ S P T T P P+ Sbjct: 5487 ANLTNVTDTRFTVTGLNQDETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQ 5546 Query: 1871 NFV--VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 ++ V V LK+ +P + + K +K S + Sbjct: 5547 EYLSEVKFRAESDVELKFNIIAK--PAPTIEWFKDGKELKPSVQLSFKHTFESTSVF-LR 5603 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988 + + + + +N++G + T ++ +K P PP ++ + V ++ + W Sbjct: 5604 DTTRLNSGSYEVKVKNSLGSACATVKLLIQ-DK----PGPPAGEIQFKKVTADNITIMWS 5658 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P +GGA + Y + R+ ++ MW V + V+ + N+ L + + Y+ R+ N+ G Sbjct: 5659 PPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCI-VNVPRLIQGNEYIFRVRGVNKYG 5717 Query: 2049 LSEPLESD 2056 + +PLES+ Sbjct: 5718 IGDPLESE 5725 Score = 181 bits (440), Expect = 2e-43 Identities = 208/901 (23%), Positives = 362/901 (40%), Gaps = 55/901 (6%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249 +E P I L + + V A L V I + +V W K + + + + S Sbjct: 3767 LEAPEIELDADLRKIVNVRATATLRLFVTIRGKPEPEVKWSKADGTLNERAQIEVTSSYT 3826 Query: 1250 KRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 L+I D +Y L L T + V V++ P + E + +K+ S V+L Sbjct: 3827 M--LVIDNVDRFDTGKYVVTLENLSGSKTAFVNVRVLDSPSAPTNLEVK-DVKQNS-VSL 3882 Query: 1308 LVDYQAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 + +IV + K+ T + S I ++ +++ N Sbjct: 3883 CWEPPLIDGGAKISHYIVEKREQKRMAFTSVCTNCVRNSYIISDLQQGGRYYFRVLAVNE 3942 Query: 1366 CG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 G A + V + + P PPGK ++L++ ++ + W++PEN G S I Y+VE Q Sbjct: 3943 LGVGLPASTDQ-VKVSEPPLPPGKVSLLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPK 4001 Query: 1423 DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 +W + + ++ L T Y FR AVN+ SDA V+K+ ++ P Sbjct: 4002 GDDKWTLCCEVKALEATVDGLSTGEEYAFRVIAVNDKGKSDAKPLISPV-VVKDITVE-P 4059 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542 + + + +D+++ F G PQP+V+W +DG+ LK + T N Sbjct: 4060 IINLLFDTYSVKAGDDLKIDVPFKGRPQPEVSWKKDGQLLK--QTTRVN-----VLTSKS 4112 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKP----VITISNEDIKQKHKVGDEWLVTAVIEG 1598 K +D G+ E + + K VI + KV + + Sbjct: 4113 SSKIVIKDATKDDTGKYEITLTSSVGTKSAVIAVIILDKPGPPSNIKVDEVSADFVSLSW 4172 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSV------IRIKELKRSHSSKYTIEASNTAG 1652 PP + N + ++ TT + S I++ L + ++ I + N G Sbjct: 4173 DPPTYDGGCQINNYVVEKRDTTTTTWQIVSATVARTSIKVTRLTQGTEYQFRIASENRYG 4232 Query: 1653 TSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 SS ++ V P +P GP + + S+ + + W P DGG +T Y IE E Sbjct: 4233 KSSAIDSVPVVAQYPFEPPGPPTNLHVAHASKYGMLVLWNRPASDGGSPVTGYHIECKEQ 4292 Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768 ++ W KV + + E Y FRV A+N G ++ V A D P Sbjct: 4293 NSLLWTKVNRGLLTENQFKMTGTEEGLMYQFRVYAENIAGIGPCTKASDAV--AARD-PC 4349 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ--EGKKWK-XXXXXXXXXAR 1825 I SV + W E +GG I + VE K+ G+ K Sbjct: 4350 EPPRNLRVTNITRTSVSLFWDKPEYDGGVKITGFIVERKELPNGRWLKCNFTNLQDTYFD 4409 Query: 1826 IQKLSINTTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVT 1883 + L+ + Y+F + A+N S P S +T+ + PP+ + + R+ Sbjct: 4410 VTGLTEDVQYEFHVIAKNSAELLSAPSESTGPVTVKDDVDPPTIILEDKLRQLVVIRAGE 4469 Query: 1884 LKWTEPESNGGS-PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 L + E G P+ ++ + K ++ K+ +I + + + + +D + ++ Sbjct: 4470 LIRLDAEITGRPLPVVSWSKDGKEIEAKARCEITSTNFNT-TLIVRDAIRRDSGQYVLTL 4528 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 N G T S +V K P PP+ PL I + + +WG P+ +GGA ++ Y Sbjct: 4529 HNVAG----TRSVAVNC-KVLDRPGPPSGPLAITGLTAEKCSLAWGPPQENGGAEIMHYI 4583 Query: 2003 IAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + R+ ++ W V G + T K + L + + Y+ R+ N+ G EPLES EP K Sbjct: 4584 VEKRETSRLAWTLVYGDMKATTCK--VTKLLKGNEYIFRVRGVNKYGDGEPLES-EPTKA 4640 Query: 2062 I 2062 + Sbjct: 4641 M 4641 Score = 176 bits (428), Expect = 6e-42 Identities = 136/537 (25%), Positives = 222/537 (41%), Gaps = 12/537 (2%) Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295 I DT KFT+ ++K R C + + K + K+E +F D + Sbjct: 987 ITDT-KFTVTKLLEKLEYQFRVCAINKVGVGEHADVPGKVLVEDKLEAPDFELD-ADMRK 1044 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 I+ S + L V + P P +W IK+ + ASL I+ V+ D+ Sbjct: 1045 MINIRAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQV--DVTGSYASLVIENVDRFDS 1102 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 G Y L EN G ++V +LD PSPP + EI +S+ + W+ P G S I +Y Sbjct: 1103 GKYTLTAENASGTKSAFISVRVLDSPSPPSNFTVKEITKNSVTLTWEPPLLDGGSKIRHY 1162 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 +VE +E + + + ++ L + FR A NE + ++ E K+ + Sbjct: 1163 IVEKRESTRKVYSPITTCNRMSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISE 1222 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535 + + + N T + + + +V + T AT + Sbjct: 1223 KPQPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVK-ALET 1281 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVG--IQQKPVI--TISNEDIKQKHKVGDEWL 1591 +K A ND G+ + + + + VI + + +VG + Sbjct: 1282 VIPNLLKGEEYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLK 1341 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + I G P P + W K+G L+ N+T + + IK+ R Y I SN Sbjct: 1342 IEVPIAGHPKPTIAWTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNAL 1401 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G + + + DKP P GPV + EIS ES+T+ W+PP GG ++ Y +EK + Sbjct: 1402 GCKDATIEVIILDKPGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTT 1461 Query: 1712 RWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 W+ V A V R T I L EY FR+ A+N G S A+ S+P++ + P Sbjct: 1462 NWMVVSATVAR--TTLKIGNLKTGAEYQFRIFAENRYGKSYAIVSDPLLAQYPFQEP 1516 Score = 175 bits (426), Expect = 1e-41 Identities = 197/898 (21%), Positives = 362/898 (40%), Gaps = 90/898 (10%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVK 1249 +EE ++ +++ A D + + + +VTW + + ++T+ S + Sbjct: 5934 LEEADLDLDVQMTTQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTER 5993 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVT 1306 TL+I K T DD +Y LL+ ++ + ++V K++D ++ +K S Sbjct: 5994 ATTLVIPKVTRDDCGKY---LLEIENGVG-EPKIVTVSLKVLDSPSACQKLLVKNVSRGE 6049 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL--TIKKVENTDAGI---YKLR 1361 L + ++A P + V + I++K T + +A T KV D + +++ Sbjct: 6050 LTLSWEA-PVIDGGCPVTNYIVEKKGSTMKAYQVITAECANTSYKVSGLDIDVAYFFRVS 6108 Query: 1362 LENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 EN G D V + P P +L+ S+ + W P++ G S I Y++E Sbjct: 6109 AENEYGVGDPCETSGPVRATETPGPVKDLVMLDSTKGSVTLQWTRPDHDGGSHITDYIIE 6168 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE----TTEYYKVI 1474 + + W + + LK N+ +FR +A NE SD S+ T + + + Sbjct: 6169 KKAQEENSWTLAATCKRCSCEVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIP 6228 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYE 1530 E + + P + ++I + F G P+P ++W +D LK ++ T + Sbjct: 6229 PEANLS----DYPNAELAVRVGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTD 6284 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFN----DHGEVETSCVVGIQQKPVITISNEDIKQKHKV 1586 N+ Y + N ++ ++ +G PV I ++IK + + Sbjct: 6285 NKTAVTVRGAKKEHAGQYTLVLDNRTIKNYFDINV-ITLGPPSVPVGPIRFDEIKAQSII 6343 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTI 1645 W G E+ Y + + + + + +I L + ++ + Sbjct: 6344 -ISWDEPKEDGG---GEITCYSVEKRETSQANWKMVCSSVVRTTFKIPNLVKGTQYQFRV 6399 Query: 1646 EASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 A N G S S++V + KP P G + ++ + +TI W+ P DGG + Y Sbjct: 6400 RAENKYGVSNPLTSLDVVAQHQYKPPGPPGKPVAYNVTSDGMTIRWEAPDFDGGSPIMGY 6459 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761 +EK + ++ W KV Y I L E EY FRV A+N G S E K Sbjct: 6460 HVEKKDRNSLMWQKVNSTIISNREYRIMGLIEGLEYSFRVYAENNAGLSPVSEQS----K 6515 Query: 1762 TALDV-PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX 1820 AL + P + +SV + W +K+GGS I+ Y VE +Q KW Sbjct: 6516 HALAISPVDPPGTPVCIDVTRDSVTLQWDTPKKDGGSKIVGYSVERRQGRGKWLRCNFTD 6575 Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + + LS ++FR+ ARN +GT ++PPS +++++ Sbjct: 6576 VSETQFTVTALSPGDRFEFRVIARNAVGT---------------ISPPSNSSGYIMTKDE 6620 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 S S ++W+ P+ + ++ G+ ++V ++ KE D+ I Sbjct: 6621 SISPEIEWS-PDQQLTLRAGENVRLSCSITGRPVPQVV---------WYKDGKEIDKRIM 6670 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 I E + G+ T P P P+ + + W PE DG + + Sbjct: 6671 -IDIEISTGIGTNT-------------PGPVEGPIRFTGITAEKCTVWWNPPENDGCSAI 6716 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 Y + R+ ++ W V +N +L + + Y RI A N+ G+ +PL+SD Sbjct: 6717 THYVVEKRETSRISWALVTS-KCEACSYNATNLIKGNEYQFRISAVNKFGVGKPLDSD 6773 Score = 174 bits (423), Expect = 3e-41 Identities = 129/465 (27%), Positives = 208/465 (44%), Gaps = 23/465 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P PE+ W K +++ + ++T + VI + + R S KYT+ A N +GT S Sbjct: 1060 VRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVI--ENVDRFDSGKYTLTAENASGTKS 1117 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 ++++V D PS P + +EI++ SVT+ W+PPL DGG ++ Y +EK E + Sbjct: 1118 AFISVRVLDSPSPPSNFTV-KEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSP 1176 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVPSXXXXXX 1774 + +R ++ ++ L E + FRV+A+N G A +EPI I P Sbjct: 1177 ITTCNR--MSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEKPQPPGKVTVVD 1234 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINT 1833 + N +V + W +GGS I Y+VE+ ++ + W I L Sbjct: 1235 ----VSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVKALETVIPNLLKGE 1290 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 YQF++ A N+ G S P + + P+ R V + S LK P + Sbjct: 1291 EYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAV-RPKVSTYSVQVGYDLKIEVPIAGH 1349 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC--IENIKEKDEIIFRISAENTVGVSLP 1951 P + + +K T V V S H+ I++ D ++ I+ N +G Sbjct: 1350 PKPTIAWTKDGIALKQ---TTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNALGCKDA 1406 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 T + + L+K P PPT P+++ + + + SW P + GG P+ Y + RD T T Sbjct: 1407 T-IEVIILDK----PGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTT 1461 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 WM V T I +L Y RI+A N G S + SD Sbjct: 1462 NWMVVSATVART-TLKIGNLKTGAEYQFRIFAENRYGKSYAIVSD 1505 Score = 171 bits (417), Expect = 1e-40 Identities = 117/371 (31%), Positives = 169/371 (45%), Gaps = 14/371 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ + + A I G P P V W K G ++ I + + I +KE R +Y + Sbjct: 650 GETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTDFVARIIVKEAIRVDGGQYILL 709 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW--KPPLDDGGLELTKYAIE 1704 N G SV + +KV D+P PEGP+ + +S E +I W KPP+ DGG +++ Y +E Sbjct: 710 VKNVGGEKSVTINVKVLDRPGPPEGPIAIYGVSNEKCSISWKPKPPVQDGGSDVSHYIVE 769 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + E W V + I KL EY+FRVI N G E LESEP++ + Sbjct: 770 RRETSRLVW-TVVEPKVQTLNLKITKLLPGNEYIFRVIPVNKYGVGEPLESEPMIARNPF 828 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXX 1823 P+ I +S+ +TW +GGSPI Y VE + ++G +W Sbjct: 829 VTPN-PPTDVEVSTITKDSMVVTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSE 887 Query: 1824 ARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP--PSQPRNFVVSESTS 1879 R + + N +Y+FR+ A N G P K L P + P N + TS Sbjct: 888 LRFRVTGLLENHSYEFRVAAENAAGVGTP---SQPTVYYKALDPVFKAGPPNNPKALDTS 944 Query: 1880 RS-VTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHEHCIENIKEKDEII 1937 RS VTL W +P +GG I YI+E W T G + + + + EK E Sbjct: 945 RSTVTLIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQ 1004 Query: 1938 FRISAENTVGV 1948 FR+ A N VGV Sbjct: 1005 FRVCAINKVGV 1015 Score = 169 bits (412), Expect = 5e-40 Identities = 169/688 (24%), Positives = 282/688 (40%), Gaps = 45/688 (6%) Query: 1204 EFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 E + + A +D L + P+ T V W K ++E EK++L + +I+ C Sbjct: 7613 ETVTISAGSDLVLDGAVGGKPEPT--VYWSKGDKILELGEKYSLTYTATRAMAVIKNCDR 7670 Query: 1261 DDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQP 1317 D Y + +A T + ++V++ P D R+ + V+ + + Sbjct: 7671 SDTGRYCLTVKNASGVKTAWVNLKVLDTPGPPADKIVISRVTEEKCTVSWKIPLEDGGDS 7730 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVT 1376 ++V + + + K+ S ++ + I+++R N G +E Sbjct: 7731 VTHYVVERRETSRLNWVLVEAECKTLSCVSSRLIKNNEYIFRVRGVNKFGPGVPLESEPV 7790 Query: 1377 ILDK----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 I PS PG P + + I W +PE+ G S I Y+V+ +E +T W V Sbjct: 7791 IARNAYTIPSQPGTPETTAVGKEHVIIEWLKPESDGGSEISNYIVDKREKSSTRWTRVNK 7850 Query: 1433 ---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP------- 1482 I T+ + L S Y+FR AVN S S+ T Y T +P Sbjct: 7851 TYTIYDTRLKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRIT 7910 Query: 1483 -TVEKPLKNITTEPNED--IELT-CIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXX 1537 T + + T P D +++ + + + WYR K LKT + Sbjct: 7911 DTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKK 7970 Query: 1538 XXXXXXXXXXYKCIAFND-HGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTA 1594 F+D EVE + + P + ++ +D+K+ + G + Sbjct: 7971 YRFRVAALNSKGTGEFSDPSSEVEP---LERTEMPDLELA-DDLKKTVCLRAGGTLRLMV 8026 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P V W K G +L++ + Y I T + + + ++++ R S KY +EA N +G Sbjct: 8027 FVTGRPTPVVAWRKTGVELQS-RGY-IETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKK 8084 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + + +KVYD P P G V +++ +RESV I W P DGG ++ Y IEK E N + Sbjct: 8085 TATILVKVYDTPGPP-GSVKVKDYTRESVVITWDVPSVDGGAHVSNYIIEKREA-NMKSY 8142 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 K + + I L E Y FRV+ +N G E E+ V+ +VPS Sbjct: 8143 KTVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVL--VCEVPSVPLDLQ 8200 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSI 1831 + SV + W +GGS + Y +E + G +W ++ I L Sbjct: 8201 IID-VTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPSLME 8259 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITI 1859 N Y FR+ A N G S P + +TI Sbjct: 8260 NDQYLFRVRATNSRGASEPMDTVTPVTI 8287 Score = 151 bits (365), Expect = 3e-34 Identities = 121/501 (24%), Positives = 211/501 (42%), Gaps = 24/501 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P PEV W K L + +T+ +++ I + R + KY + N +G+ + Sbjct: 3796 IRGKPEPEVKWSKADGTLNERAQIEVTSSY--TMLVIDNVDRFDTGKYVVTLENLSGSKT 3853 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V ++V D PS P + ++++ + SV++ W+PPL DGG +++ Y +EK E + Sbjct: 3854 AFVNVRVLDSPSAPTN-LEVKDVKQNSVSLCWEPPLIDGGAKISHYIVEKREQKRMAFTS 3912 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 V + +Y I L + Y FRV+A N +G ++ + + P Sbjct: 3913 VC-TNCVRNSYIISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSE----PPLPPGKVS 3967 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQKLSINTT 1834 + +V ++W E +GGS I +Y VE++ +G KW A + LS Sbjct: 3968 LLDVTRHTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLCCEVKALEATVDGLSTGEE 4027 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y FR+ A N+ G S + + K +T + S LK P Sbjct: 4028 YAFRVIAVNDKGKSDAKPLISPVVV-KDITVEPIINLLFDTYSVKAGDDLKIDVPFKGRP 4086 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 P ++ + + +K + ++T S + I++ + D + I+ ++VG + Sbjct: 4087 QPEVSWKKDGQLLKQTTRVNVLT-SKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIA 4145 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 + L+K P PP + +++ V ++ V SW P +DGG + Y + RD T T W Sbjct: 4146 VII-LDK----PGPP-SNIKVDEVSADFVSLSWDPPTYDGGCQINNYVVEKRDTTTTTWQ 4199 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPG 2074 V T + L++ Y RI + N G S ++S +P + E PG Sbjct: 4200 IVSATVART-SIKVTRLTQGTEYQFRIASENRYGKSSAIDS------VPVVAQYPFEPPG 4252 Query: 2075 EQTEVXXXXXXXXXXXXXWLR 2095 T + W R Sbjct: 4253 PPTNLHVAHASKYGMLVLWNR 4273 Score = 144 bits (348), Expect = 3e-32 Identities = 171/793 (21%), Positives = 304/793 (38%), Gaps = 62/793 (7%) Query: 1349 KVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 K+ N +AG+ +K+ EN G + V V +D PP I++I +++ + W+ Sbjct: 5400 KITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEPPLNLRIIDITKNTVTLSWE 5459 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 +P G S I Y++E +E ++ W ++ N+T T+ ++ L + +Y FR A N V Sbjct: 5460 KPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQDETYEFRVMARNAVG 5519 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 +T +P +E P L + D+EL P P + W++ Sbjct: 5520 SLSNPSMIAGPATCVDT-YGAPEIEIPQEYLSEVKFRAESDVELKFNIIAKPAPTIEWFK 5578 Query: 1518 DGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 DGK+LK + K T+E+ Y+ N G + + IQ KP Sbjct: 5579 DGKELKPSVQLSFKHTFES-TSVFLRDTTRLNSGSYEVKVKNSLGSACATVKLLIQDKPG 5637 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT--SVI 1630 +I+ K D + ++ + K E + EK ++ Sbjct: 5638 PPAG--EIQFKKVTADNITIMWSPPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCIV 5695 Query: 1631 RIKELKRSHSSKYTIEASNTAGT-----SSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 + L + + + + N G S + + PS+P P + I++ ++T+ Sbjct: 5696 NVPRLIQGNEYIFRVRGVNKYGIGDPLESEPVIAKNAFVPPSEPSKPKVTM-ITKSTMTV 5754 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQ 1744 W+ P DGG ++ Y +EK E + +W KV RD + L EN EY FRV A Sbjct: 5755 IWERPALDGGSDIDGYYLEKREKKSLQWFKVVKGTIRDTRQK-VSNLVENNEYQFRVCAV 5813 Query: 1745 NPVGFSEALESEPIV-IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G E+ + +D+P + S+ + W +GGS I Y Sbjct: 5814 NKAGAGNYSEASDLYRAYDPIDLPGEPSKLRVVDSTKS-SITLGWEKPIYDGGSEITHYV 5872 Query: 1804 VE-IKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 ++ + E ++W + L T Y F++ A N G D K Sbjct: 5873 LDQMNTEEREWVTINPQVKACEYVVSHLKPGTYYFFKVSAVNCKGKG----EDIK----- 5923 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI-IEFKTVKGKSWTKIVTVGG 1920 + P Q ++ + V + T+ + G + +I ++ + +W + Sbjct: 5924 -MYQPVQAKDILEEADLDLDVQMT-TQYTARAGRDVEIFIPLKGRPAPNVTWRRGDRNMA 5981 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP----SPPTA--PLE 1974 + + + I + + ++ + G L V K TV P+A L Sbjct: 5982 ADNRYTISSTERATTLVIPKVTRDDCGKYLLEIENGVGEPKIVTVSLKVLDSPSACQKLL 6041 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 ++ V + SW P DGG P+ Y + + T + + NT + + L + Sbjct: 6042 VKNVSRGELTLSWEAPVIDGGCPVTNYIVEKKGSTMKAYQVITAECANT-SYKVSGLDID 6100 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWL 2094 Y R+ A NE G+ +P E+ P + A E PG ++ W Sbjct: 6101 VAYFFRVSAENEYGVGDPCETSGPVR--------ATETPGPVKDLVMLDSTKGSVTLQWT 6152 Query: 2095 R-EHNMDADIRSY 2106 R +H+ + I Y Sbjct: 6153 RPDHDGGSHITDY 6165 Score = 141 bits (342), Expect = 2e-31 Identities = 113/422 (26%), Positives = 183/422 (43%), Gaps = 28/422 (6%) Query: 1642 KYTIEASNTAG------TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGG 1695 +Y + A N G S + V D P +PE ++ +R SV + W PP DGG Sbjct: 2168 EYRVYAENIVGIGKCSKVSEICVAQDPCDPPGRPEALIV----TRHSVKLRWTPPQYDGG 2223 Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALE 1754 +T Y +EK + +W+K + + + + L E+ +Y FR+IA+N G S+ E Sbjct: 2224 SLITGYVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSE 2283 Query: 1755 SE-PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID---YKVEIKQEG 1810 S I K +D P + ++ T+ G PI +K +++ E Sbjct: 2284 STGSITAKDEVDPPKYETDPMYNQMLVVKAGE-TFNLEATVEGKPIPTAQWFKGDVEVEN 2342 Query: 1811 KKWKXXXXXXXXXARIQKLSINTTY-QFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQ 1868 + K ++ Q+ + N GT S+P++ K L P Sbjct: 2343 SARAEIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSV-------KVLDRPGP 2395 Query: 1869 PRN-FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 VS T +L W P +GG+ +++YII+ + +WT + + G+ Sbjct: 2396 SEGPLTVSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVT 2455 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 + +K +E IFR+ A N GV P ES V + P PP LEI + + + W Sbjct: 2456 KLLKG-NEYIFRVMAVNKYGVGEPLESVPVIMRNPFVPPGPPQE-LEITNITRDSMTVCW 2513 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 PE +GG+ ++GY I RD W + K V L+F + L+E+H Y R+ A N Sbjct: 2514 NRPETNGGSTIVGYIIEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVA 2573 Query: 2048 GL 2049 G+ Sbjct: 2574 GV 2575 Score = 138 bits (335), Expect = 1e-30 Identities = 171/736 (23%), Positives = 288/736 (39%), Gaps = 64/736 (8%) Query: 1358 YKLRLEN--NCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 Y++ EN G + + P PPG+P L + S+ + W P+ G S I Sbjct: 2169 YRVYAENIVGIGKCSKVSEICVAQDPCDPPGRPEALIVTRHSVKLRWTPPQYDGGSLITG 2228 Query: 1415 YVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYY 1471 YVVE +++ +W+ S NIT+ + ++ L +S Y FR A N IS SE+T Sbjct: 2229 YVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTG-- 2286 Query: 1472 KVIKETKIQSPTVE-KPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKA 1527 + + ++ P E P+ N + + E L G P P W++ D + +A+A Sbjct: 2287 SITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVENSARA 2346 Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-----VITISNED 1579 +N + Y + N G V + +P +T+SN Sbjct: 2347 EIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLTVSN-- 2404 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRS 1638 + K WL G I K + + + + + + ++ ++ +L + Sbjct: 2405 -VTEEKCSLSWLPPRHDGGAGVSHYIIQK---RETSRLTWTVVSSDCGATMFKVTKLLKG 2460 Query: 1639 HSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGP---VIMREISRESVTIEWKPPLDDG 1694 + + + A N G +E + P P GP + + I+R+S+T+ W P +G Sbjct: 2461 NEYIFRVMAVNKYGVGEPLESVPVIMRNPFVPPGPPQELEITNITRDSMTVCWNRPETNG 2520 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 G + Y IEK + RW K + + L E+ EY FRV A+N G Sbjct: 2521 GSTIVGYIIEKRDRAGVRWTKCNKRRVTDLRFRVTGLTEDHEYEFRVSAENVAGVXXXXX 2580 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813 K + +S+ ++W +GG I Y VEI K + ++W Sbjct: 2581 P---TFKPGCPTNAHVVDTR------KDSISLSWHRPIYDGGCEIQGYAVEITKADEEEW 2631 Query: 1814 KXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLP------YTSDDKITIGKTLT 1864 A I KL + Y+ RI A N++G P DKI + + Sbjct: 2632 VICTPPTGVNATKFTITKLIEHQEYKVRICAINKLGVGEPTEVPGVVKPIDKIEPPEVIL 2691 Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 + VV S + + P +P + E + GK V G + Sbjct: 2692 DSDLRKGIVVRAGGSMRICI----PFKGRPTPEIRWAKEDAELPGKVQ---VETGEDYSQ 2744 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 I+ + D + ++ EN+ G T+S V + K P P L ++ + V Sbjct: 2745 LSIDICDKYDAGKYILTLENSAG----TKSAFVSV-KVLDTPGAP-VNLTVKDIKRESVT 2798 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 +W P DGGA + Y + R+ T+ ++ V T + + DL E Y R+ A Sbjct: 2799 LTWEPPLIDGGARIKNYLVEKRESTRKVYSNVDNKCTKT-SYRVTDLKEGTLYYFRVLAE 2857 Query: 2045 NEIGLSEPLESDEPFK 2060 NE G+ E E+++ K Sbjct: 2858 NEFGVGEAAETEDSVK 2873 Score = 137 bits (332), Expect = 3e-30 Identities = 97/343 (28%), Positives = 158/343 (46%), Gaps = 18/343 (5%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 + + A N G S++ + IV+ LD PS + +SV + W +GGSP Sbjct: 5217 YDITASNSSGTSKSFLN--IVV---LDRPSAPQGPVELFDVTEDSVSLKWLAPAYDGGSP 5271 Query: 1799 IIDYKVEIKQEGK-KWKXXXXXXXX-XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 I +Y ++ ++ W +I KL+ YQFRI A N+ G S + Sbjct: 5272 ITNYIIQKRETTTANWMDVSSAVARCTMKIMKLTTGLEYQFRIRAENKYGIS-EHIDSPP 5330 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI- 1915 +++ T P P ++ T +T+ W EP+S+GGS + Y ++ K W ++ Sbjct: 5331 VSVNLPYTVPEAPSTPEITAVTRECITVAWKEPKSDGGSHVFGYHLQMKDKNSILWQRVN 5390 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 TV + H I NI F+++AEN GVS+ ++ L A P PL + Sbjct: 5391 KTVIRATHFK-ITNINAGLIYEFKVAAENAAGVSVFSKVSDAVLAIDACEP-----PLNL 5444 Query: 1976 RMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033 R++ N V SW P +DGG+P+ GY I ++ + + W + +V +F + L++ Sbjct: 5445 RIIDITKNTVTLSWEKPNYDGGSPITGYIIEKKEGSSSRWFKANLTNVTDTRFTVTGLNQ 5504 Query: 2034 NHTYMIRIYARNEIG-LSEPLESDEPFKVIPGEGSHADEEPGE 2075 + TY R+ ARN +G LS P P + G+ E P E Sbjct: 5505 DETYEFRVMARNAVGSLSNPSMIAGPATCVDTYGAPEIEIPQE 5547 Score = 135 bits (326), Expect = 1e-29 Identities = 112/432 (25%), Positives = 184/432 (42%), Gaps = 25/432 (5%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYD---KPSKPEGPVIMREISRESVT 1684 R+ L +HS ++ + A N AG S V K D K P P + + SR +VT Sbjct: 891 RVTGLLENHSYEFRVAAENAAGVGTPSQPTVYYKALDPVFKAGPPNNPKAL-DTSRSTVT 949 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIA 1743 + W P+ DGG E+ Y +E ++ W +T + + KL E EY FRV A Sbjct: 950 LIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQFRVCA 1009 Query: 1744 QNPVGFSEALESE-PIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIID 1801 N VG E + ++++ L+ P I+ + + F + +P I Sbjct: 1010 INKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIK 1069 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 + + + + I+ + + ++ + A N GT + S + Sbjct: 1070 WGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLTAENASGTKSAFISV------R 1123 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 L PS P NF V E T SVTL W P +GGS I +YI+E + K ++ I T Sbjct: 1124 VLDSPSPPSNFTVKEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSPITTCNRM 1183 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + +E + E FR+ AEN GV LP + ++ +++ + P PP + + V + Sbjct: 1184 SWK--VEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEK---PQPP-GKVTVVDVSN 1237 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 V +W P DGG+ + Y + + W V L+ I +L + Y + Sbjct: 1238 TTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVC--ATVKALETVIPNLLKGEEYQFK 1295 Query: 2041 IYARNEIGLSEP 2052 + A N+ G S+P Sbjct: 1296 VSAINDKGKSDP 1307 Score = 133 bits (321), Expect = 6e-29 Identities = 104/431 (24%), Positives = 185/431 (42%), Gaps = 25/431 (5%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDK---PSKPEGPVIMREISRESVT 1684 R+ L HS ++ + A N AG S+ +KV D P P P + + S +V+ Sbjct: 3627 RVTGLTEGHSYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNPKVT-DHSSTTVS 3685 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET--YCIQKLNENCEYMFRVI 1742 + W P+ DGG +T Y +E E ++ W+ + V+ Y ++KL EN EY FR+ Sbjct: 3686 LSWSRPIYDGGANITGYVVEMKEAADDEWV-ICTPPTGVQATHYTVRKLRENAEYSFRIC 3744 Query: 1743 AQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID-NESVYITWFPSEKNGGSPII 1800 A N G E ++ VI L+ P ++ + + F + + P + Sbjct: 3745 AVNYEGLGEHVDLPGSVIAAEKLEAPEIELDADLRKIVNVRATATLRLFVTIRGKPEPEV 3804 Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 + ++ + I + T ++ + N G+ + + Sbjct: 3805 KWSKADGTLNERAQIEVTSSYTMLVIDNVDRFDTGKYVVTLENLSGSKTAFVN------V 3858 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 + L PS P N V + SV+L W P +GG+ I++YI+E + K ++T + T Sbjct: 3859 RVLDSPSAPTNLEVKDVKQNSVSLCWEPPLIDGGAKISHYIVEKREQKRMAFTSVCT-NC 3917 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + I ++++ FR+ A N +GV LP + V++ + P P + + V Sbjct: 3918 VRNSYIISDLQQGGRYYFRVLAVNELGVGLPASTDQVKVSE----PPLPPGKVSLLDVTR 3973 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + V SW PE DGG+ + Y + ++ W +V L+ + LS Y R Sbjct: 3974 HTVTLSWEKPENDGGSKITNYIVEMQPKGDDKWTLC--CEVKALEATVDGLSTGEEYAFR 4031 Query: 2041 IYARNEIGLSE 2051 + A N+ G S+ Sbjct: 4032 VIAVNDKGKSD 4042 Score = 132 bits (319), Expect = 1e-28 Identities = 146/610 (23%), Positives = 247/610 (40%), Gaps = 35/610 (5%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKT 1436 K PP P L+ S++ + W +P G I Y+VE + EW + IT T Sbjct: 931 KAGPPNNPKALDTSRSTVTLIWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDT 990 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL---KNITT 1493 + ++ L Y+FR A+N+V + + ++ KV+ E K+++P E K I Sbjct: 991 KFTVTKLLEKLEYQFRVCAINKVGVGEHADVPG--KVLVEDKLEAPDFELDADMRKMINI 1048 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCI 1551 + L G P P++ W + DG+ +TA+ + Y Sbjct: 1049 RAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLT 1108 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 A N G V + P SN +K+ K+ V W +++G ++ Y Sbjct: 1109 AENASGTKSAFISVRVLDSP-SPPSNFTVKEITKNSVTLTW-EPPLLDG--GSKIRHYIV 1164 Query: 1610 GNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDK 1665 + K Y+ ITT + S +++ L + + A N G + + +K+ +K Sbjct: 1165 EKRESTRKVYSPITTCNRMS-WKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKISEK 1223 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P +P G V + ++S +V++ W+ P+ DGG ++ Y +E D+ W A V + +ET Sbjct: 1224 P-QPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATV-KALET 1281 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 I L + EY F+V A N G S+ + V+ L + + Sbjct: 1282 -VIPNLLKGEEYQFKVSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDL 1340 Query: 1786 ITWFPSEKNGGSPIIDYK--VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 P + I K + +KQ + I+ + + + I N Sbjct: 1341 KIEVPIAGHPKPTIAWTKDGIALKQT-TRVNVTDSTHQTTLTIKDATRDDGGMYNINISN 1399 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 +G + ++ I PP+ P V E ++ S+TL W P GG PI+NY++E Sbjct: 1400 ALGCK---DATIEVIILDKPGPPTGP--VKVDEISAESITLSWEPPSYTGGCPISNYVVE 1454 Query: 1904 FKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + +W + TV + + I N+K E FRI AEN G S S + + Sbjct: 1455 KRDTTTTNWMVVSATVARTTLK--IGNLKTGAEYQFRIFAENRYGKSYAIVSDPLLAQYP 1512 Query: 1963 ATVPSPPTAP 1972 P PP P Sbjct: 1513 FQEPGPPGTP 1522 Score = 132 bits (319), Expect = 1e-28 Identities = 86/298 (28%), Positives = 139/298 (46%), Gaps = 7/298 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXX-X 1821 LD P + E + W P ++NGG+ I+ Y VE ++ + W Sbjct: 4544 LDRPGPPSGPLAITGLTAEKCSLAWGPPQENGGAEIMHYIVEKRETSRLAWTLVYGDMKA 4603 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 ++ KL Y FR+ N+ G P S+ + T P+ P N V+ TS + Sbjct: 4604 TTCKVTKLLKGNEYIFRVRGVNKYGDGEPLESEPTKAMDP-FTVPTPPTNVQVTAVTSEA 4662 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 +T+ W P S+GGS I+ Y+IE + G W ++ N++E E +R+ Sbjct: 4663 MTICWERPVSDGGSSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRVF 4722 Query: 1942 AENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 AEN+ G+S P+ ++ E +PSPP P + + + + SW P +DGGAP+ G Sbjct: 4723 AENSAGLSAPSIPCPLIKAEDPQFLPSPPAKPKIVDSTKTTVTL-SWNKPLFDGGAPVTG 4781 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL-ESDE 2057 Y + R W+ + NT +F + L+ Y+ I + N+IG+SEP ESD+ Sbjct: 4782 YRVEYRKTLDDEWVVAVQNTKNT-EFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDK 4838 Score = 130 bits (313), Expect = 5e-28 Identities = 95/319 (29%), Positives = 136/319 (42%), Gaps = 9/319 (2%) Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKX 1815 P+ +K LD P + E Y+ W +GG+ I Y +E ++ + W Sbjct: 3458 PVTVKV-LDRPGPPDGPLEVKGVTAEKCYLHWSHPTHDGGASISHYIIEKRETSRLSWTM 3516 Query: 1816 XXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV 1874 + +I KL Y FR+ A N+ G P S+ I T PS P Sbjct: 3517 VEPKIQAISYKITKLLPGNEYIFRVTAVNKYGVGEPLESEPVIA-RNPFTTPSAPSTPEA 3575 Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 S T S+ L W PESNGG+ I YI+E + G WTK + + + E Sbjct: 3576 SAITRDSIVLTWERPESNGGADIEGYILEKRDKDGVRWTKCNKKRLNDLRFRVTGLTEGH 3635 Query: 1935 EIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 F++SAEN GV P+ S+ +++ P PP P ++ S V SW P +D Sbjct: 3636 SYEFKVSAENAAGVGKPSAPSEYIKVCDAVYPPGPPNNP-KVTDHSSTTVSLSWSRPIYD 3694 Query: 1994 GGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 GGA + GY + +++ W+ V + +R L EN Y RI A N GL E Sbjct: 3695 GGANITGYVVEMKEAADDEWVICTPPTGVQATHYTVRKLRENAEYSFRICAVNYEGLGEH 3754 Query: 2053 LESDEPFKVIPGEGSHADE 2071 + D P VI E A E Sbjct: 3755 V--DLPGSVIAAEKLEAPE 3771 Score = 124 bits (300), Expect = 2e-26 Identities = 103/398 (25%), Positives = 173/398 (43%), Gaps = 15/398 (3%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQT 1438 P+PP P I + SI++ W P G S + YVVE E + +W + K + + Sbjct: 7901 PAPPSVPRITDTTKHSISMTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEF 7960 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNE 1497 L N YRFR A+N + S+ + + ++ T++ + LK + Sbjct: 7961 VAAGLAANKKYRFRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGG 8020 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 + L G P P V W + G +L++ T ++ Y A N Sbjct: 8021 TLRLMVFVTGRPTPVVAWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENP 8080 Query: 1556 HGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 G+ + +V + P ++ +D ++ V W V +V G I K + Sbjct: 8081 SGKKTATILVKVYDTPGPPGSVKVKDYTRESVV-ITWDVPSVDGGAHVSNYIIEKREANM 8139 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVT--LKVYDKPSKPE 1670 ++ K +TT+ + ++ RI L+ + + N G E T + V + PS P Sbjct: 8140 KSYK--TVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLVCEVPSVPL 8197 Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730 I+ ++++ SVT+ W+ PL DGG LT Y IE + ++RW VA V + I Sbjct: 8198 DLQII-DVTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPS 8256 Query: 1731 LNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVP 1767 L EN +Y+FRV A N G SE +++ P+ I+ +P Sbjct: 8257 LMENDQYLFRVRATNSRGASEPMDTVTPVTIQDIKVIP 8294 Score = 122 bits (293), Expect = 1e-25 Identities = 87/289 (30%), Positives = 123/289 (42%), Gaps = 8/289 (2%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA-RIQKLSINTTYQ 1836 I E + W P E +G S I Y VE ++ + W + L YQ Sbjct: 6696 ITAEKCTVWWNPPENDGCSAITHYVVEKRETSRISWALVTSKCEACSYNATNLIKGNEYQ 6755 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 FRI A N+ G P SD I T P P + T S+T+ WT P S+GG+ Sbjct: 6756 FRISAVNKFGVGKPLDSDPVIA-QMQYTVPDAPGTPDATHVTGNSITMCWTRPRSDGGNE 6814 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 I YI+E + K W K+ + H + N+ E +E FR+ AEN GV P S Sbjct: 6815 IKQYILERREKKSLRWVKVSSKRAITELRHRVTNLTEGNEYEFRVMAENGAGVG-PASST 6873 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S RL K S P+AP I+++ S + V W P +DGG ++GYNI + + W Sbjct: 6874 S-RLFKCREPTSAPSAPTVIKVIDSTKSSVTIEWTKPVFDGGMEIIGYNIDMCKASLEEW 6932 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI 2062 V ++ + L Y R+ A N G E P + + Sbjct: 6933 HRVNSQICIHTRYTAKGLVPGELYKFRVSAVNGSGEGEASVMPNPVQAL 6981 Score = 121 bits (291), Expect = 3e-25 Identities = 107/441 (24%), Positives = 180/441 (40%), Gaps = 21/441 (4%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKVY--DKPSKPEGPVIMR--EISRESVT 1684 +++ L ++ + A N AG S + T + D P P + R + ++ S++ Sbjct: 7859 LKVTGLLEGSEYQFRVTAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRITDTTKHSIS 7918 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + W P+ DGG +++ Y +E E + +W + + L N +Y FRV A Sbjct: 7919 MTWTRPMYDGGSDVSGYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKKYRFRVAAL 7978 Query: 1745 NPVGFSE----ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 N G E + E EP+ D+ ++ + F + + +P++ Sbjct: 7979 NSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP--TPVV 8036 Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 ++ + + ++K+S + ++ + A N G + Sbjct: 8037 AWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKKTA------TILV 8090 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 K P P + V + T SV + W P +GG+ ++NYIIE + KS+ K VT Sbjct: 8091 KVYDTPGPPGSVKVKDYTRESVVITWDVPSVDGGAHVSNYIIEKREANMKSY-KTVTTEC 8149 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 I ++E FR+ EN GV P E+ L VPS P L+I V Sbjct: 8150 RKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLV--CEVPSVPL-DLQIIDVTK 8206 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + V W P DGG+ L GY I + W V + +F I L EN Y+ R Sbjct: 8207 SSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIPSLMENDQYLFR 8266 Query: 2041 IYARNEIGLSEPLESDEPFKV 2061 + A N G SEP+++ P + Sbjct: 8267 VRATNSRGASEPMDTVTPVTI 8287 Score = 119 bits (286), Expect = 1e-24 Identities = 161/786 (20%), Positives = 291/786 (37%), Gaps = 57/786 (7%) Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTI 1377 ++I+ + K + K S L + T+ Y+ R+ EN G + Sbjct: 6817 QYILERREKKSLRWVKVSSKRAITELRHRVTNLTEGNEYEFRVMAENGAGVGPASSTSRL 6876 Query: 1378 L---DKPSPPGKPNILE-IDS--SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 + S P P +++ IDS SS+ I W +P G II Y ++ + EW V Sbjct: 6877 FKCREPTSAPSAPTVIKVIDSTKSSVTIEWTKPVFDGGMEIIGYNIDMCKASLEEWHRVN 6936 Query: 1432 N--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 + T+ + + L Y+FR AVN +AS + + ++ K Sbjct: 6937 SQICIHTRYTAKGLVPGELYKFRVSAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFK 6996 Query: 1490 NITTEPN-EDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXX-XXXXXX 1546 T N + L F G P P TW + DG+ A N Sbjct: 6997 QTHTVKNGGTVTLQVAFRGKPAPLATWSKADGELPIMADVNTTNTSSTLTIEGCTRYEAG 7056 Query: 1547 XYKCIAFNDHGEVETSCVVGI--------------QQKPVITISNEDIKQKHKVGDEWLV 1592 Y N+ G + + + +P+I ++ V D Sbjct: 7057 KYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEPAPPKRLDVIDTTSS 7116 Query: 1593 TAVIEGIPP-----PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 TA + + P + Y + + ++ ++ + K+ + ++ L + + ++A Sbjct: 7117 TASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVEGLIENREYDFRVKA 7176 Query: 1648 SNTAGTSSVEVTL-KVYDKPSKPEGPVIMREISRESVTIEWKP------PLDDGGLELTK 1700 N AG S + T V K + E + I+ + +T + P+ Sbjct: 7177 KNDAGISEPQGTFGSVVIKEPRIEPTADLSSITNQLITCKISNSFTIDIPISGRPAPKVI 7236 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVI 1760 + +E+ + I + D + T ++ + + ++ +N G + +V Sbjct: 7237 WKLEEMKLKETDRILIRTTD-ERTTLLVRDSKRSDSGKYYLVLENSAGVKTFTVTVAVVG 7295 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWK-XXXX 1818 + PS + +ES ++W +GG+ I +Y VE ++ G W+ Sbjct: 7296 R-----PSPPTGPVEVSGVSSESCTLSWSEPADDGGTDITNYIVEKRESGSASWQVVNSS 7350 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 ++ L+ Y FR+ A N+ G S S + I PS P V + Sbjct: 7351 VKRTTIKVTHLTKYMEYTFRVCAENKFGVSKSVES-TPVVIKHPFVAPSPPTRPDVVSVS 7409 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 + ++ +KW P ++GGS IT Y IE K W + + + + N+ E E F Sbjct: 7410 ANAIGIKWDVPYADGGSKITGYWIEKKERNTILWVRENKLPCLECHYKVSNLIEGLEYQF 7469 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 R+ A N G+S +E+ L A P P E+ + + W P DGG+ + Sbjct: 7470 RVYAMNIAGLSKASEASRPIL---ALNPVDPPGKPEVTDITRSSASLCWTVPFNDGGSKI 7526 Query: 1999 LGYNI-----AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL-SEP 2052 +GY + + + W++ + F + LSE TY + A+N G+ S Sbjct: 7527 VGYVVERKVYSADEWDDNRWLKCNYTTITENYFTVTGLSEEETYEYHVIAKNAAGVHSAA 7586 Query: 2053 LESDEP 2058 ES P Sbjct: 7587 SESSGP 7592 Score = 118 bits (283), Expect = 2e-24 Identities = 123/544 (22%), Positives = 214/544 (39%), Gaps = 66/544 (12%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G+ ++ I G P P+V+WYK+G ++ DK I Sbjct: 6637 RAGENVRLSCSITGRPVPQVVWYKDGKEI--DKRIMID---------------------- 6672 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 IE S GT++ P EGP+ I+ E T+ W PP +DG +T Y +E Sbjct: 6673 IEISTGIGTNT----------PGPVEGPIRFTGITAEKCTVWWNPPENDGCSAITHYVVE 6722 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 K E W V + +Y L + EY FR+ A N G + L+S+P++ + Sbjct: 6723 KRETSRISWALVTS-KCEACSYNATNLIKGNEYQFRISAVNKFGVGKPLDSDPVIAQMQY 6781 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXX 1823 VP N S+ + W +GG+ I Y +E +++ +W Sbjct: 6782 TVPDAPGTPDATHVTGN-SITMCWTRPRSDGGNEIKQYILERREKKSLRWVKVSSKRAIT 6840 Query: 1824 A---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSR 1880 R+ L+ Y+FR+ A N G ++ + + PS P V +ST Sbjct: 6841 ELRHRVTNLTEGNEYEFRVMAENGAGVGPASSTSRLFKCREPTSAPSAPTVIKVIDSTKS 6900 Query: 1881 SVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 SVT++WT+P +GG I Y I+ + W ++ + + + + + FR+ Sbjct: 6901 SVTIEWTKPVFDGGMEIIGYNIDMCKASLEEWHRVNSQICIHTRYTAKGLVPGELYKFRV 6960 Query: 1941 SAENTVGVS----LPTESQSV------------RLEKHATVPSPPTAPLEIRMVGSNIVM 1984 SA N G +P Q++ ++ TV + T L++ G + Sbjct: 6961 SAVNGSGEGEASVMPNPVQALDRLTSPEIDIDANFKQTHTVKNGGTVTLQVAFRGKPAPL 7020 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWME-VGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 +W + DG P++ ++ + + T+ +E + + ++ + S + I Sbjct: 7021 ATWS--KADGELPIMA-DVNTTNTSSTLTIEGCTRYEAGKYTLSLENNSGRKSITFTIKV 7077 Query: 2044 RNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLR-EHNMDAD 2102 + G P+ FK + E A EEP + WL+ EH+ + Sbjct: 7078 LDTPGPPGPI----AFKDMT-EPIIATEEPAPPKRLDVIDTTSSTASLVWLKPEHDGGSR 7132 Query: 2103 IRSY 2106 IR Y Sbjct: 7133 IRGY 7136 Score = 114 bits (275), Expect = 2e-23 Identities = 80/304 (26%), Positives = 129/304 (42%), Gaps = 9/304 (2%) Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXX 1822 LD P + E ++W ++GG + Y VE ++ + W Sbjct: 7696 LDTPGPPADKIVISRVTEEKCTVSWKIPLEDGGDSVTHYVVERRETSRLNWVLVEAECKT 7755 Query: 1823 XARIQ-KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + + +L N Y FR+ N+ G +P S+ I T PSQP + Sbjct: 7756 LSCVSSRLIKNNEYIFRVRGVNKFGPGVPLESEPVIA-RNAYTIPSQPGTPETTAVGKEH 7814 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRI 1940 V ++W +PES+GGS I+NYI++ + WT++ + + E E FR+ Sbjct: 7815 VIIEWLKPESDGGSEISNYIVDKREKSSTRWTRVNKTYTIYDTRLKVTGLLEGSEYQFRV 7874 Query: 1941 SAENTVGVSLPTESQSVRLEKHAT-VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 +A N G S P+++ L + T P+PP+ P +I MT W P +DGG+ + Sbjct: 7875 TAVNAAGQSQPSDATPYILCRDPTYTPAPPSVPRITDTTKHSISMT-WTRPMYDGGSDVS 7933 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESD 2056 GY + I + W + T +F L+ N Y R+ A N G S+P Sbjct: 7934 GYVVEILEEGSEQWYRATTKPLKTNEFVAAGLAANKKYRFRVAALNSKGTGEFSDPSSEV 7993 Query: 2057 EPFK 2060 EP + Sbjct: 7994 EPLE 7997 Score = 113 bits (272), Expect = 5e-23 Identities = 107/453 (23%), Positives = 183/453 (40%), Gaps = 36/453 (7%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV--EVTLKVYDKPSKPEGP--VIMREISRE 1681 K + ++ +L + + + + N G K D + P P V + ++ E Sbjct: 4602 KATTCKVTKLLKGNEYIFRVRGVNKYGDGEPLESEPTKAMDPFTVPTPPTNVQVTAVTSE 4661 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 ++TI W+ P+ DGG ++ Y IEK E RW +V L E CEY +RV Sbjct: 4662 AMTICWERPVSDGGSSISGYVIEKREKTGLRWCRVNKKPVYDLRVKASNLREGCEYEYRV 4721 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT--WFPSEKNGGSPI 1799 A+N G S S P + A D +D+ +T W +GG+P+ Sbjct: 4722 FAENSAGLSAP--SIPCPLIKAEDPQFLPSPPAKPKIVDSTKTTVTLSWNKPLFDGGAPV 4779 Query: 1800 IDYKVEIKQE-GKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 Y+VE ++ +W + KL+ Y F I + N+IG S P DK Sbjct: 4780 TGYRVEYRKTLDDEWVVAVQNTKNTEFTVVKLTPGAEYVFVIKSINKIGVSEPSPESDKQ 4839 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK--- 1914 + P F +S +++ +K +G S + K V +W K Sbjct: 4840 VAKEREEEPV----FEISNEMRKTLIVK------DGSSFTMTVPFKGKPVPTVTWNKPDV 4889 Query: 1915 ------IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 ++ + +E +D + ++ N G + + + +VR+ P Sbjct: 4890 DLRVRAVIDTTDTFTSISLEQANREDSGKYTVTLSNVAGTT--SLALNVRV---LDSPGA 4944 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 P A +E++ V + +W TPE +GG P+ Y + IR+ +K W + + L + + Sbjct: 4945 P-ARVEVKDVTKSSATVTWDTPENEGGGPVKNYLVDIREASKKGWTRLTDT-CHRLTYKV 5002 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 +L E Y R+ NE G P E+ E K+ Sbjct: 5003 TNLQEGGVYYFRVTGENEYGTGLPAETKEGTKI 5035 Score = 113 bits (271), Expect = 7e-23 Identities = 73/259 (28%), Positives = 121/259 (46%), Gaps = 11/259 (4%) Query: 1210 ANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 +NT L E P D ++ Y+ + +D+E +T+ + VK +I + ++ ++ Sbjct: 1236 SNTTVSLAWEKPVHDGGSRISHYEVEVAPKDSEAWTVCATVKALETVIPNLLKGEEYQFK 1295 Query: 1268 CVLLDAKSTT---KLKVEVVE----FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 ++ K + +L VV P + Y ++ G D+ + V P+P Sbjct: 1296 VSAINDKGKSDPRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLKIEVPIAGHPKPTIA 1355 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W + +K+ + + +LTIK D G+Y + + N G D + V ILDK Sbjct: 1356 WTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNALGCKDATIEVIILDK 1415 Query: 1381 PSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT 1438 P PP G + EI + SI + W+ P TG I YVVE ++ TT W+ V + +T Sbjct: 1416 PGPPTGPVKVDEISAESITLSWEPPSYTGGCPISNYVVEKRDTTTTNWMVVSATVARTTL 1475 Query: 1439 SIQNLKTNSSYRFRAYAVN 1457 I NLKT + Y+FR +A N Sbjct: 1476 KIGNLKTGAEYQFRIFAEN 1494 Score = 112 bits (269), Expect = 1e-22 Identities = 62/200 (31%), Positives = 98/200 (49%), Gaps = 2/200 (1%) Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 K L P P + V++ T+ L W P +GG+ I +II+ + +WT + T Sbjct: 287 KVLDRPGPPDSLTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAWTNVAT-DL 345 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + + + +E IFR+ A N GV P ES+ V + + VPS P E+ + Sbjct: 346 QANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV-ICTNPYVPSDPPGQPEVTTITK 404 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + ++ W PE DGG+ + Y I RD T W++ K V L+F + L+ H Y R Sbjct: 405 DSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTVTDLRFKVSGLTLGHEYEFR 464 Query: 2041 IYARNEIGLSEPLESDEPFK 2060 ++A N GLS+P S +K Sbjct: 465 VFAENNAGLSQPSLSSPFYK 484 Score = 108 bits (259), Expect = 2e-21 Identities = 105/419 (25%), Positives = 170/419 (40%), Gaps = 26/419 (6%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P V + I+++S+ + W+ P +DGG + Y +EK + D RW + + + Sbjct: 833 PPTDVEVSTITKDSMVVTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSELRFRV 892 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE--SVYI 1786 L EN Y FRV A+N G S+P V ALD +D +V + Sbjct: 893 TGLLENHSYEFRVAAENAAGVGTP--SQPTVYYKALDPVFKAGPPNNPKALDTSRSTVTL 950 Query: 1787 TWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXX---XXXXXXARIQKLSINTTYQFRIYAR 1842 W +GG I Y VE +W + KL YQFR+ A Sbjct: 951 IWGKPIYDGGCEIQGYIVEACNGASDEWFTCTPPTGITDTKFTVTKLLEKLEYQFRVCAI 1010 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS--RSVTLKWTEPESNGGSPITNY 1900 N++G K+ + L P + + + + + TL+ P +P + Sbjct: 1011 NKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIKW 1070 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 +K T V V GS IEN+ D + ++AEN G + SVR+ Sbjct: 1071 GKADGEIKE---TAQVDVTGSYASLVIENVDRFDSGKYTLTAENASGTK--SAFISVRV- 1124 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 PSPP+ ++ + N V +W P DGG+ + Y + R+ T+ ++ + Sbjct: 1125 --LDSPSPPSN-FTVKEITKNSVTLTWEPPLLDGGSKIRHYIVEKRESTRKVYSPI--TT 1179 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 N + + + L E + R+ A NE G+ P + EP K+ S + PG+ T V Sbjct: 1180 CNRMSWKVEPLPEGGIFFFRVLAENEYGVGLPAKIAEPIKI-----SEKPQPPGKVTVV 1233 Score = 107 bits (256), Expect = 4e-21 Identities = 89/321 (27%), Positives = 133/321 (41%), Gaps = 18/321 (5%) Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 F + A NP GF++ + + LD P + E + W +GG+ Sbjct: 269 FTLTASNPGGFAKFTFNVKV-----LDRPGPPDSLTVTD-VTAEKCVLNWLHPTHDGGAK 322 Query: 1799 IIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 I +Y + K+E + W ++ KL Y FR+ A N+ G P S+ Sbjct: 323 I-EYFIIQKRETSRLAWTNVATDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEP 381 Query: 1856 KITIGKTLT--PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 I + PP QP V+ T S+ + W PE +GGS I Y+IE + G W Sbjct: 382 VICTNPYVPSDPPGQPE---VTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWV 438 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAP 1972 K + + + E FR+ AEN G+S P+ S + E +P PP P Sbjct: 439 KCNKRTVTDLRFKVSGLTLGHEYEFRVFAENNAGLSQPSLSSPFYKAEDTIFMPGPPGNP 498 Query: 1973 LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW-MEVGKVDVNTLKFNIRDL 2031 + S+I + SW P +DGG+ + GY + + W + K F I +L Sbjct: 499 RVLDTTKSSITL-SWNKPVYDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATSFTITNL 557 Query: 2032 SENHTYMIRIYARNEIGLSEP 2052 EN Y I I A N G+ EP Sbjct: 558 KENQEYKINISATNCEGVGEP 578 Score = 104 bits (249), Expect = 3e-20 Identities = 102/385 (26%), Positives = 158/385 (41%), Gaps = 28/385 (7%) Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 + +EW P DGG + Y +E+ E ++ W K+ + L E EY +RV Sbjct: 2113 MVVEWHKPPSDGGSAILGYHLERKEKNSILWTKINKTLIQDCRFKSTPLEEGIEYEYRVY 2172 Query: 1743 AQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 A+N VG + + SE V + D P + SV + W P + +GGS I Sbjct: 2173 AENIVGIGKCSKVSEICVAQDPCDPPG----RPEALIVTRHSVKLRWTPPQYDGGSLITG 2228 Query: 1802 YKVEIKQ--EGKKWKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGT-SLPYTSDDKI 1857 Y VE + EGK K + L+ ++ Y FRI A+N G S P S I Sbjct: 2229 YVVEKRDVPEGKWMKASFTNITELEFTVTGLTEDSKYDFRIIAKNAAGAISKPSESTGSI 2288 Query: 1858 TIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK-IV 1916 T + PP + ++ + +K E + +E K + W K V Sbjct: 2289 TAKDEVDPP----KYETDPMYNQMLVVKAGETFN------LEATVEGKPIPTAQWFKGDV 2338 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRIS-----AENTVGVSLPTESQSVRLE-KHATVPSPPT 1970 V S I+N K ++ + + + T+ ++ ++SV K P P Sbjct: 2339 EVENSARAE-IKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSE 2397 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 PL + V SW P DGGA + Y I R+ ++ W V D F + Sbjct: 2398 GPLTVSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSS-DCGATMFKVTK 2456 Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055 L + + Y+ R+ A N+ G+ EPLES Sbjct: 2457 LLKGNEYIFRVMAVNKYGVGEPLES 2481 Score = 100 bits (239), Expect = 5e-19 Identities = 56/198 (28%), Positives = 94/198 (47%), Gaps = 2/198 (1%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 PP P + S++ K P +GGS +++YI+E + WT + +++ Sbjct: 731 PPEGPIAIYGVSNEKCSISWKPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNL 790 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 I + +E IFR+ N GV P ES+ + P+PPT +E+ + + ++ Sbjct: 791 K-ITKLLPGNEYIFRVIPVNKYGVGEPLESEPMIARNPFVTPNPPT-DVEVSTITKDSMV 848 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 +W P DGG+P+ GY + RD W K V+ L+F + L ENH+Y R+ A Sbjct: 849 VTWERPANDGGSPIQGYIVEKRDKDGVRWTRCNKRTVSELRFRVTGLLENHSYEFRVAAE 908 Query: 2045 NEIGLSEPLESDEPFKVI 2062 N G+ P + +K + Sbjct: 909 NAAGVGTPSQPTVYYKAL 926 Score = 99 bits (238), Expect = 7e-19 Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 15/199 (7%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG-GS 1921 + PP +P V+ +T VTL WT P+ +GG +T Y++E K W K + G Sbjct: 24 IDPPGKPDVINVTRNT---VTLMWTPPKYDGGHKLTGYVVE----KSGDWWKGLDEGTNH 76 Query: 1922 VH----EHCIENIKEKDEIIFRISAENTVG-VSLPTES-QSVRLEKHATVPSPPTAPLEI 1975 V+ + + ++ E + FR+ A+N+ G V +P+ES + + + P PP+ P EI Sbjct: 77 VNIQGCAYTVTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTP-EI 135 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 V N V SW P DGG+ + GY + ++ W+ K V L+F ++ LSE Sbjct: 136 DNVSRNAVTISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGV 195 Query: 2036 TYMIRIYARNEIGLSEPLE 2054 Y R+ A N+ G EP E Sbjct: 196 EYEFRVTAENKAGFGEPRE 214 Score = 94.3 bits (224), Expect = 3e-17 Identities = 71/339 (20%), Positives = 140/339 (41%), Gaps = 11/339 (3%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK 1249 +E P + + I + A + L V + T ++ W K I++T + + Sbjct: 1031 LEAPDFELDADMRKMINIRAASTLRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYA 1090 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +L+I D +YT +A T + V V++ P ++ + K +T Sbjct: 1091 --SLVIENVDRFDSGKYTLTAENASGTKSAFISVRVLDSPSPPSNFTVKEITKNSVTLTW 1148 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 +IV + + K P S ++ + +++ EN G Sbjct: 1149 EPPLLDGGSKIRHYIVEKRESTR-KVYSPITTCNRMSWKVEPLPEGGIFFFRVLAENEYG 1207 Query: 1368 ---HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 A + + I +KP PPGK ++++ ++++++ W++P + G S I +Y VE D+ Sbjct: 1208 VGLPAKIAEPIKISEKPQPPGKVTVVDVSNTTVSLAWEKPVHDGGSRISHYEVEVAPKDS 1267 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 W + +T I NL Y+F+ A+N+ SD + + V+ + P V Sbjct: 1268 EAWTVCATVKALETVIPNLLKGEEYQFKVSAINDKGKSDPRQLAQ--SVVARDLVIHPAV 1325 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 + + + D+++ G P+P + W +DG LK Sbjct: 1326 RPKVSTYSVQVGYDLKIEVPIAGHPKPTIAWTKDGIALK 1364 Score = 91.5 bits (217), Expect = 2e-16 Identities = 99/417 (23%), Positives = 174/417 (41%), Gaps = 20/417 (4%) Query: 1134 DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 D + W KDG ++ + + ++ K+ I D + DDAG+Y+ NS TA + Sbjct: 3005 DPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTITATNSVGTATEEITV 3064 Query: 1194 PSINFTLRLPEFILVPANTDAYLTV--EIPDET--LDVTWYKKKSVIEDTEKFTLISDVK 1249 ++ + + + Y+T+ E P+ T + Y + T + ++S Sbjct: 3065 IILDKPGPPTGPVKIEEVSSNYVTLSWEPPEYTGGCQINNYIVEKRDTTTTAWQIVSATI 3124 Query: 1250 KRTLI-IRKCTEDDQCEYTCVLLD--AKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDV 1305 RT I + K + ++ + KS + VV ++P I + Sbjct: 3125 ARTTIKVTKLKTGIEYQFRVSAENRYGKSPAIVSPAVVAQYPFTQPVAPGTPTISAATKD 3184 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDAGI-YKLRL 1362 T+ V+++A ++ I +K K++ ++ T K + GI Y+ R+ Sbjct: 3185 TMTVEWKAPTNNGGSPVLGYHIERKEKNSLLWTKLNKLLIPDTHFKTAELEEGIEYEFRV 3244 Query: 1363 --ENNCGHAD---VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 EN G ++ + + D PPG P +EI + + + W P+ G S I YVV Sbjct: 3245 YAENMAGLSEASKISESTVARDPCDPPGTPEAIEITRNHVTLQWTRPQYDGGSAITGYVV 3304 Query: 1418 EYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI-SDASETTEYYKVI 1474 E ++ T W+ S NI TQ ++ L + Y FR A N I S SE+T Sbjct: 3305 ERKKHPDTRWMKASFTNIIDTQFTVTGLTEDCVYEFRVIARNAASICSRPSESTGEITAK 3364 Query: 1475 KETKIQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530 E + T++ K++T E + + G P P+V W +DGK++ A E Sbjct: 3365 DEIEAPEATMDSKFKDLTIVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRME 3421 Score = 79.8 bits (188), Expect = 8e-13 Identities = 65/203 (32%), Positives = 92/203 (45%), Gaps = 19/203 (9%) Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 V L D P KP+ VI ++R +VT+ W PP DGG +LT Y +EK + W K Sbjct: 19 VALDPIDPPGKPD--VI--NVTRNTVTLMWTPPKYDGGHKLTGYVVEK----SGDWWKGL 70 Query: 1718 D-----VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV--PSXX 1770 D V+ Y + L E +Y FRV A+N G + + SE + T D P Sbjct: 71 DEGTNHVNIQGCAYTVTDLTEGSQYQFRVRAKNSAG-AVGVPSESTELLTCKDEYGPPGP 129 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXXXAR--IQ 1827 + +V I+W ++GGS I Y VE K++ G +W R +Q Sbjct: 130 PSTPEIDNVSRNAVTISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQ 189 Query: 1828 KLSINTTYQFRIYARNEIGTSLP 1850 LS Y+FR+ A N+ G P Sbjct: 190 GLSEGVEYEFRVTAENKAGFGEP 212 Score = 78.2 bits (184), Expect = 2e-12 Identities = 62/238 (26%), Positives = 99/238 (41%), Gaps = 24/238 (10%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX------XARIQKLSIN 1832 + +V + W P + +GG + Y VE + G WK + L+ Sbjct: 35 VTRNTVTLMWTPPKYDGGHKLTGYVVE--KSGDWWKGLDEGTNHVNIQGCAYTVTDLTEG 92 Query: 1833 TTYQFRIYARNEIGT-SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 + YQFR+ A+N G +P S + +T PP P + + +VT+ W P Sbjct: 93 SQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNVSRNAVTISWKRPAQ 152 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 +GGS I Y +E K +G W + ++ + E E FR++AEN G P Sbjct: 153 DGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAENKAGFGEP 212 Query: 1952 TESQSVRLEKHAT---VPS----------PPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996 E +LE + T +PS TA +EI+ + V+ + + DGGA Sbjct: 213 RE--VFKLEANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGA 268 Score = 74.1 bits (174), Expect = 4e-11 Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 8/130 (6%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVE------VTLK-VYDKPSKPEGPVIMREISRESVT 1684 + +L ++ + A N+AG V +T K Y P P P I +SR +VT Sbjct: 86 VTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEI-DNVSRNAVT 144 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 I WK P DGG ++ Y +E+ E RW++ + + +Q L+E EY FRV A+ Sbjct: 145 ISWKRPAQDGGSDIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAE 204 Query: 1745 NPVGFSEALE 1754 N GF E E Sbjct: 205 NKAGFGEPRE 214 Score = 73.3 bits (172), Expect = 7e-11 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 9/189 (4%) Query: 1287 PPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 PPKI D E +Y + G TL P P+ W+ + I + + Sbjct: 632 PPKI-DLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTDFV 690 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 A + +K+ D G Y L ++N G V +NV +LD+P PP P I + + +I W Sbjct: 691 ARIIVKEAIRVDGGQYILLVKNVGGEKSVTINVKVLDRPGPPEGPIAIYGVSNEKCSISW 750 Query: 1402 --DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNE 1458 P G S + +Y+VE +E W V+ +T I L + Y FR VN+ Sbjct: 751 KPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNLKITKLLPGNEYIFRVIPVNK 810 Query: 1459 VDISDASET 1467 + + E+ Sbjct: 811 YGVGEPLES 819 Score = 70.5 bits (165), Expect = 5e-10 Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 7/159 (4%) Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILD 1379 +I+ + + T + D ++ L + K+ + I+++ N G + +E I Sbjct: 326 FIIQKRETSRLAWTNVATDLQANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVICT 385 Query: 1380 KP----SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNI 1433 P PPG+P + I S+ +CW+ PE+ G S I YV+E ++ W+ + + + Sbjct: 386 NPYVPSDPPGQPEVTTITKDSMVVCWERPEHDGGSRINTYVIERRDKTGLRWVKCNKRTV 445 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 T + + L Y FR +A N +S S ++ +YK Sbjct: 446 TDLRFKVSGLTLGHEYEFRVFAENNAGLSQPSLSSPFYK 484 Score = 70.5 bits (165), Expect = 5e-10 Identities = 50/228 (21%), Positives = 90/228 (39%), Gaps = 8/228 (3%) Query: 1273 AKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 ++ST + + PPK Y + +K G L + P P +W ++ Sbjct: 2282 SESTGSITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGKPIPTAQWFKGDVEVE 2341 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-N 1388 + A L +K D G Y L L N G V +V +LD+P P P Sbjct: 2342 NSARAEIKNTDFKALLVVKDAVRVDGGQYTLVLNNVAGTKSVPFSVKVLDRPGPSEGPLT 2401 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNS 1447 + + ++ W P + G + + +Y+++ +E W V + T + L + Sbjct: 2402 VSNVTEEKCSLSWLPPRHDGGAGVSHYIIQKRETSRLTWTVVSSDCGATMFKVTKLLKGN 2461 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITTE 1494 Y FR AVN+ + + E+ +++ + P E + NIT + Sbjct: 2462 EYIFRVMAVNKYGVGEPLESVPV--IMRNPFVPPGPPQELEITNITRD 2507 Score = 67.3 bits (157), Expect = 4e-09 Identities = 83/385 (21%), Positives = 162/385 (42%), Gaps = 35/385 (9%) Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 KK + ++ + GE+S +S+ + E P + L + + + A L V Sbjct: 7969 KKYRFRVAALNSKGTGEFSDP--SSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMV 8026 Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 + V ++K V + + +D L++ K + D +Y + K T Sbjct: 8027 FVTGRPTPVVAWRKTGVELQSRGYIETTD-SYTCLMVEKVSRYDSGKYVVEAENPSGKKT 8085 Query: 1277 TKLKVEVVEFPP-----KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 + V+V + P K+ DY RE ++++ + P + V++ II+K Sbjct: 8086 ATILVKVYDTPGPPGSVKVKDYTRE---------SVVITWDV-PSVDGGAHVSNYIIEKR 8135 Query: 1332 KHTKPSIDSKSASL--TIKKVENTDAGI---YKLRLENNCG---HADVEMNVTILDKPSP 1383 + S + + T+ ++ + G+ +++ EN G + +V + + PS Sbjct: 8136 EANMKSYKTVTTECRKTLFRITGLEEGLHYFFRVLPENIYGVGEPCETTESVLVCEVPSV 8195 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQ 1441 P I+++ SS+ + W++P + G S + YV+E ++ + W ++ + +Q +I Sbjct: 8196 PLDLQIIDVTKSSVTLHWEKPLHDGGSRLTGYVIEACKLGSDRWSTVATTKASVSQFTIP 8255 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK---PLKNITTEPNED 1498 +L N Y FR A N S+ +T I++ K+ P ++ P K + Sbjct: 8256 SLMENDQYLFRVRATNSRGASEPMDTVTPV-TIQDIKV-IPKIDLSSIPQKVAYVHRGKP 8313 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523 IEL P P +WY G KLK Sbjct: 8314 IELRIPVKAKPLPVCSWYFGGVKLK 8338 Score = 65.3 bits (152), Expect = 2e-08 Identities = 72/308 (23%), Positives = 132/308 (42%), Gaps = 31/308 (10%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKF 1242 T + T P I + A +D L I P T++ W+K ++ + + Sbjct: 5532 TCVDTYGAPEIEIPQEYLSEVKFRAESDVELKFNIIAKPAPTIE--WFKDGKELKPSVQL 5589 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYR 1298 + + ++ +R T + Y + + A +T KL ++ PP E +++ Sbjct: 5590 SFKHTFESTSVFLRDTTRLNSGSYEVKVKNSLGSACATVKLLIQDKPGPPA---GEIQFK 5646 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKP--SIDSKSASLTIKKVENTD 1354 ++T++ + P DE +V I++K + ++ SI S+ I V Sbjct: 5647 KVTADNITIM-----WSPPADEGGAMVTHYIVEKRETSRVMWSIVSEKLVDCIVNVPRLI 5701 Query: 1355 AG---IYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPEN 1406 G I+++R N G D + ++ K PS P KP + I S++ + W+ P Sbjct: 5702 QGNEYIFRVRGVNKYGIGDPLESEPVIAKNAFVPPSEPSKPKVTMITKSTMTVIWERPAL 5761 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 G S I Y +E +E + +W V I T+ + NL N+ Y+FR AVN+ + Sbjct: 5762 DGGSDIDGYYLEKREKKSLQWFKVVKGTIRDTRQKVSNLVENNEYQFRVCAVNKAGAGNY 5821 Query: 1465 SETTEYYK 1472 SE ++ Y+ Sbjct: 5822 SEASDLYR 5829 Score = 63.7 bits (148), Expect = 5e-08 Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 1/154 (0%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P+ W + K ++ + L K D G + L N G A N Sbjct: 226 PIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPGGFAKFTFN 285 Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNI 1433 V +LD+P PP + ++ + + W P + G + I Y++++ +E W +V ++ Sbjct: 286 VKVLDRPGPPDSLTVTDVTAEKCVLNWLHPTHDGGAKIEYFIIQKRETSRLAWTNVATDL 345 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 + + L + Y FR AVN+ + + E+ Sbjct: 346 QANRLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 379 Score = 61.3 bits (142), Expect = 3e-07 Identities = 63/305 (20%), Positives = 127/305 (41%), Gaps = 19/305 (6%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTL 1244 TA V+ P I+ + + ++V A L I + L V W K+ I + + + Sbjct: 625 TAKDEVDPPKIDLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEI 684 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 + +I+++ D +Y ++ + + + + V+V++ P E I Sbjct: 685 KNTDFVARIIVKEAIRVDGGQYILLVKNVGGEKSVTINVKVLDRPGPP---EGPIAIYGV 741 Query: 1303 SDVTLLVDYQAFPQPND------EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 S+ + ++ P D +IV + + T ++ +L I K+ + Sbjct: 742 SNEKCSISWKPKPPVQDGGSDVSHYIVERRETSRLVWTVVEPKVQTLNLKITKLLPGNEY 801 Query: 1357 IYKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNST 1411 I+++ N G + + ++ + P+PP + I S+ + W+ P N G S Sbjct: 802 IFRVIPVNKYGVGEPLESEPMIARNPFVTPNPPTDVEVSTITKDSMVVTWERPANDGGSP 861 Query: 1412 IIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I Y+VE ++ D W + + +++ + + L N SY FR A N + S+ T Sbjct: 862 IQGYIVEKRDKDGVRWTRCNKRTVSELRFRVTGLLENHSYEFRVAAENAAGVGTPSQPTV 921 Query: 1470 YYKVI 1474 YYK + Sbjct: 922 YYKAL 926 Score = 57.6 bits (133), Expect = 4e-06 Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 5/108 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW---ISVKNITKTQ 1437 P PPG P +L+ SSI + W++P G S I Y+VE + EW K T T Sbjct: 492 PGPPGNPRVLDTTKSSITLSWNKPVYDGGSEITGYIVETCLPEEDEWTIHTPKKGWTATS 551 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 +I NLK N Y+ A N + + + K E ++ P +E Sbjct: 552 FTITNLKENQEYKINISATNCEGVGEPAAVPGIPKA--EDRLLPPEIE 597 Score = 55.2 bits (127), Expect = 2e-05 Identities = 63/303 (20%), Positives = 123/303 (40%), Gaps = 18/303 (5%) Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKK-KSVIEDTEKFT 1243 TA +E P + + +V A + + + L +V W K K V + T + Sbjct: 3362 TAKDEIEAPEATMDSKFKDLTIVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRME 3421 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302 + + + + L ++ C D + L++ + V V V P D E + G Sbjct: 3422 VKTTLTRTILTVKDCIRVDGGHFVLKLVNVGGVKMVPVTVKVLDRPGPPDGPLEVK---G 3478 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDSKSASLTIK--KVENTDAGI 1357 + + P + ++ II+K + ++ S ++ K +++ K K+ + I Sbjct: 3479 VTAEKCYLHWSHPTHDGGASISHYIIEKRETSRLSWTMVEPKIQAISYKITKLLPGNEYI 3538 Query: 1358 YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 +++ N G + + ++ + PS P P I SI + W+ PE+ G + I Sbjct: 3539 FRVTAVNKYGVGEPLESEPVIARNPFTTPSAPSTPEASAITRDSIVLTWERPESNGGADI 3598 Query: 1413 IYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 Y++E ++ D W + K + + + L SY F+ A N + S +EY Sbjct: 3599 EGYILEKRDKDGVRWTKCNKKRLNDLRFRVTGLTEGHSYEFKVSAENAAGVGKPSAPSEY 3658 Query: 1471 YKV 1473 KV Sbjct: 3659 IKV 3661 Score = 50.8 bits (116), Expect = 4e-04 Identities = 43/171 (25%), Positives = 66/171 (38%), Gaps = 10/171 (5%) Query: 1358 YKLRLENNCGHADVEMNVTIL-------DKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 +++R +N+ G V T L P PP P I + +++ I W P G S Sbjct: 97 FRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNVSRNAVTISWKRPAQDGGS 156 Query: 1411 TIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 I Y VE +E W+ S + + + +Q L Y FR A N+ + E Sbjct: 157 DIRGYCVERKEKRGMRWVRASKRTVPDLRFKVQGLSEGVEYEFRVTAENKAGFGEPREVF 216 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 + + I S K K + +I+ T F V K + RDG Sbjct: 217 KLEANVTGRPIPSLVWTKDGKELEDTAKMEIK-TFDFHTVLVNKDSLRRDG 266 Score = 48.0 bits (109), Expect = 0.003 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 8/151 (5%) Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKI-KTGEKE 733 D+ VA+++ + +V+K+T ++ + + ++N+ G E S ++ K E+E Sbjct: 4791 DDEWVVAVQNTKNTEFTVVKLTPGAEY---VFVIKSINKIGVSEPSPESDKQVAKEREEE 4847 Query: 734 PPQVI--EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 P I E K++IV+ G S ++ G P PT+TW K + ++ DT + Sbjct: 4848 PVFEISNEMRKTLIVKDGSSFTMTVPFKGKPVPTVTWNKPDVDLRVRAVIDTTDTFTSIS 4907 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 L+ +D G YT+ N G + + V Sbjct: 4908 LEQANREDSGKYTVTLSNVAGTTSLALNVRV 4938 Score = 47.6 bits (108), Expect = 0.004 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 8/121 (6%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-----YQEIDTTEWISVKN 1432 LD PPGKP+++ + +++ + W P+ G + YVVE ++ +D E + N Sbjct: 21 LDPIDPPGKPDVINVTRNTVTLMWTPPKYDGGHKLTGYVVEKSGDWWKGLD--EGTNHVN 78 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 I ++ +L S Y+FR A N + SE+TE E P + N+ Sbjct: 79 IQGCAYTVTDLTEGSQYQFRVRAKNSAGAVGVPSESTELLTCKDEYGPPGPPSTPEIDNV 138 Query: 1492 T 1492 + Sbjct: 139 S 139 Score = 46.8 bits (106), Expect = 0.007 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 9/133 (6%) Query: 697 ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGE 750 IT + + QE + A+N+ G +P V+K + EPP+VI + K ++VR G Sbjct: 2647 ITKLIEHQEYKVRICAINKLGVGEPTEVPGVVK-PIDKIEPPEVILDSDLRKGIVVRAGG 2705 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 S+ + G P P I W K + + G+ +S + D G Y L ENS Sbjct: 2706 SMRICIPFKGRPTPEIRWAKEDAELPGKVQVETGEDYSQLSIDICDKYDAGKYILTLENS 2765 Query: 811 EGIAETSAVITVE 823 G SA ++V+ Sbjct: 2766 AG--TKSAFVSVK 2776 Score = 46.8 bits (106), Expect = 0.007 Identities = 35/134 (26%), Positives = 60/134 (44%), Gaps = 5/134 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVIL 754 +T + E + V A N +G + P+ + + P + ++ GE++ + Sbjct: 2937 VTGLSTGHEYMFRVSAFNEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKI 2996 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENSEG 812 V+G P P I W K+ + +K + +T S T +K D G YT+ A NS G Sbjct: 2997 DIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKIYIKDANKDDAGKYTITATNSVG 3056 Query: 813 IA-ETSAVITVEEP 825 A E VI +++P Sbjct: 3057 TATEEITVIILDKP 3070 Score = 46.4 bits (105), Expect = 0.009 Identities = 36/135 (26%), Positives = 65/135 (48%), Gaps = 7/135 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---PPQVIEPLKSMIVRQGESVI 753 I N+ K +E + V A+N +G++ P L ++ P V + + V+ G + Sbjct: 1283 IPNLLKGEEYQFKVSAINDKGKSD-PRQLAQSVVARDLVIHPAVRPKVSTYSVQVGYDLK 1341 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITI-LKPKKVKDEGVYTLKAENSE 811 + + G+P+PTI W K+ +K + D TH T+ +K D G+Y + N+ Sbjct: 1342 IEVPIAGHPKPTIAWTKDGIALKQTTRVNVTDSTHQTTLTIKDATRDDGGMYNINISNAL 1401 Query: 812 GIAE-TSAVITVEEP 825 G + T VI +++P Sbjct: 1402 GCKDATIEVIILDKP 1416 Score = 45.6 bits (103), Expect = 0.015 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 3/92 (3%) Query: 1968 PPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF 2026 PP P ++ V N V W P++DGG L GY + D K + V++ + Sbjct: 26 PPGKP-DVINVTRNTVTLMWTPPKYDGGHKLTGYVVEKSGDWWKGLDEGTNHVNIQGCAY 84 Query: 2027 NIRDLSENHTYMIRIYARNEIG-LSEPLESDE 2057 + DL+E Y R+ A+N G + P ES E Sbjct: 85 TVTDLTEGSQYQFRVRAKNSAGAVGVPSESTE 116 Score = 45.6 bits (103), Expect = 0.015 Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 8/100 (8%) Query: 718 EASLPIVLKIKTGEKEPPQVI--EPLKSMIV-RQGESVILSAQVVGNPRPTITWCKNNKP 774 E++ P+ +K + +PP +I + L+ ++V R GE + L A++ G P P ++W K+ K Sbjct: 4437 ESTGPVTVK---DDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPVVSWSKDGKE 4493 Query: 775 VKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENSEG 812 ++A T+ T I++ +D G Y L N G Sbjct: 4494 IEAKARCEITSTNFNTTLIVRDAIRRDSGQYVLTLHNVAG 4533 Score = 45.2 bits (102), Expect = 0.020 Identities = 57/254 (22%), Positives = 99/254 (38%), Gaps = 26/254 (10%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI--KTGEKEPPQVIEPLKSMIVRQGE 750 S L I +++ G YT+ N G S+ +K+ G P + + +I + Sbjct: 7043 STLTIEGCTRYEAGKYTLSLENNSGRKSITFTIKVLDTPGPPGPIAFKDMTEPIIATEEP 7102 Query: 751 SVILSAQVVGNPRPT--ITWCKNNKP---------VKALPTKSD-----GDTHSITILKP 794 + V+ T + W K V+ SD G+T S+ +L Sbjct: 7103 APPKRLDVIDTTSSTASLVWLKPEHDGGSRIRGYVVEYRAKGSDQWLLSGETKSLKMLVE 7162 Query: 795 KKVKD-EGVYTLKAENSEGIAE---TSAVITVEEPT-EENAEPPLFINRFQEITVKEKGT 849 +++ E + +KA+N GI+E T + ++EP E A+ N Q IT K + Sbjct: 7163 GLIENREYDFRVKAKNDAGISEPQGTFGSVVIKEPRIEPTADLSSITN--QLITCKISNS 7220 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + ++ P P + W + ++ I E L++ + DSG Y V Sbjct: 7221 FTIDIPISGRPAPKVIWKLEEMKLKETDRILIRTTDERTTLLVRD-SKRSDSGKYYLVLE 7279 Query: 910 NSAGKSSHGARVTI 923 NSAG + V + Sbjct: 7280 NSAGVKTFTVTVAV 7293 Score = 43.6 bits (98), Expect = 0.061 Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVA 854 K E + + A N G+ E A + + E+ E P F + + I ++ T++L Sbjct: 1000 KLEYQFRVCAINKVGVGE-HADVPGKVLVEDKLEAPDFELDADMRKMINIRAASTLRLFV 1058 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V P P I W + + I ET + G LVI NVD DSG Y A N++G Sbjct: 1059 PVRGRPTPEIKWGKADGEI--KETAQVDVTGSYASLVIENVD-RFDSGKYTLTAENASGT 1115 Query: 915 SS 916 S Sbjct: 1116 KS 1117 Score = 43.2 bits (97), Expect = 0.081 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 5/116 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNP 860 + + A NS+G E S + EP E P L + + + + ++ GT++L+ VT P Sbjct: 7973 FRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP 8032 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P + W R + S + D L++ V S DSG Y A N +GK + Sbjct: 8033 TPVVAW-RKTGVELQSRGYIETTDSYTC-LMVEKV-SRYDSGKYVVEAENPSGKKT 8085 Score = 42.3 bits (95), Expect = 0.14 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 9/125 (7%) Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQVI---EPLKSMIVR 747 CS ++T +K+ + V A N +G + + I + PP+ P + VR Sbjct: 6186 CSC-EVTGLKENAVLQFRVFAKNEKGNSDFSQIGPITVQDFVIPPEANLSDYPNAELAVR 6244 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804 G+++ + G PRP I+W K+N P+K + ++ + ++T+ KK + G YT Sbjct: 6245 VGQNIHIELPFKGKPRPVISWLKDNLPLKESEKIRFRTTDNKTAVTVRGAKK-EHAGQYT 6303 Query: 805 LKAEN 809 L +N Sbjct: 6304 LVLDN 6308 Score = 41.9 bits (94), Expect = 0.19 Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 4/118 (3%) Query: 489 NEK--IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 NEK D P+ T+++ ++ P F +G ++ + V G P P+I W + Sbjct: 2954 NEKGRSDPRPLAAPVTAKDATIHPAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKD 3013 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS-STTELIVEAP 603 +K + + + + + I++ +DAG +T A N+ G A+ T +I++ P Sbjct: 3014 GQALKETTRLNV-SNTKSSTKIYIKDANKDDAGKYTITATNSVGTATEEITVIILDKP 3070 Score = 41.5 bits (93), Expect = 0.25 Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ E + G+P+P I W + +K + + D + TL I++ +D G + Sbjct: 1337 GYDLKIEVPIAGHPKPTIAWTKDGIALKQTTRVNV-TDSTHQTTLTIKDATRDDGGMYNI 1395 Query: 584 VAKNAAGFASSTTELIV 600 NA G +T E+I+ Sbjct: 1396 NISNALGCKDATIEVII 1412 Score = 41.5 bits (93), Expect = 0.25 Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 11/154 (7%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLK---IKTGEKEPPQV-IEPL--KSMIVRQGE 750 +T + + + + ++A N G S P E +PP+ +P+ + ++V+ GE Sbjct: 2256 VTGLTEDSKYDFRIIAKNAAGAISKPSESTGSITAKDEVDPPKYETDPMYNQMLVVKAGE 2315 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + L A V G P PT W K + V+ A + D ++ ++K D G YTL Sbjct: 2316 TFNLEATVEGKPIPTAQWFKGDVEVENSARAEIKNTDFKALLVVKDAVRVDGGQYTLVLN 2375 Query: 809 NSEGIAETS-AVITVEEPTEENAEPPLFINRFQE 841 N G +V ++ P +E PL ++ E Sbjct: 2376 NVAGTKSVPFSVKVLDRPGP--SEGPLTVSNVTE 2407 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKV--KDEG 801 IV GE+ I+ A G P P + W K+ K V KA P T + TIL K D G Sbjct: 3383 IVHAGETFIIDADYTGKPLPEVIWLKDGKEVDKATPRMEVKTTLTRTILTVKDCIRVDGG 3442 Query: 802 VYTLKAENSEGIAETSAVITV 822 + LK N G+ + V Sbjct: 3443 HFVLKLVNVGGVKMVPVTVKV 3463 Score = 41.1 bits (92), Expect = 0.33 Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 5/126 (3%) Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT--VKEKGTIKLVARVT 857 E V+ +K+ N G++E S + E EP I+ T VK+ + + Sbjct: 4816 EYVFVIKSINKIGVSEPSPESDKQVAKEREEEPVFEISNEMRKTLIVKDGSSFTMTVPFK 4875 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 PVP++TW + + + I +I L N + DSG Y SN AG +S Sbjct: 4876 GKPVPTVTWNKPDVDLRVRAVIDTTDTFTSISLEQANRE---DSGKYTVTLSNVAGTTSL 4932 Query: 918 GARVTI 923 V + Sbjct: 4933 ALNVRV 4938 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/126 (21%), Positives = 57/126 (45%), Gaps = 3/126 (2%) Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV--KEKGTIKLVARVT 857 E + ++AEN G +ET ++ ++ P + + F TV + T+K + Sbjct: 5112 EYFFRVRAENHAGFSETKEMVNAVVVKDQFECPEINMKNFPHNTVYVRAGSTLKCEIPLM 5171 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P+P ++ ++N + + ++I++++ + DSG Y ASNS+G S Sbjct: 5172 GRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVAG-DSGRYDITASNSSGTSKS 5230 Query: 918 GARVTI 923 + + Sbjct: 5231 FLNIVV 5236 Score = 40.7 bits (91), Expect = 0.43 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T E VEG P P WF+ ++ S ++ + D A LV+++ D G +T Sbjct: 2314 GETFNLEATVEGKPIPTAQWFKGDVEVENSARAEI-KNTDFKALLVVKDAVRVDGGQYTL 2372 Query: 584 VAKNAAGFAS 593 V N AG S Sbjct: 2373 VLNNVAGTKS 2382 Score = 40.3 bits (90), Expect = 0.57 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 8/118 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHM 690 I P F + G ++ ++ ++ P+P I W G+ + ++V+ +S + Sbjct: 2975 IHPAFKMTFNTYSIQNGENLKIDIPVIGCPDPKIEWKKDGQALKETTRLNVSNTKSSTKI 3034 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKEPPQVIEPLKSMIV 746 Y I + K G YT+ A N G A+ + +++ K G P IE + S V Sbjct: 3035 Y-----IKDANKDDAGKYTITATNSVGTATEEITVIILDKPGPPTGPVKIEEVSSNYV 3087 Score = 40.3 bits (90), Expect = 0.57 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 8/115 (6%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790 E E PQ E L + R V L ++ P PTI W K+ K +K S T T Sbjct: 5541 EIEIPQ--EYLSEVKFRAESDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFEST 5598 Query: 791 --ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 L+ + G Y +K +NS G SA TV+ ++ PP +F+++T Sbjct: 5599 SVFLRDTTRLNSGSYEVKVKNSLG----SACATVKLLIQDKPGPPAGEIQFKKVT 5649 Score = 39.9 bits (89), Expect = 0.75 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 754 LSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L A V G P P++ W K+ K ++ A D H++ + K +D G +TL A N Sbjct: 218 LEANVTGRPIPSLVWTKDGKELEDTAKMEIKTFDFHTVLVNKDSLRRDGGAFTLTASNPG 277 Query: 812 GIAE-TSAVITVEEP 825 G A+ T V ++ P Sbjct: 278 GFAKFTFNVKVLDRP 292 Score = 39.9 bits (89), Expect = 0.75 Identities = 34/131 (25%), Positives = 62/131 (47%), Gaps = 7/131 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREG---EASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGES 751 +T + + E + V A+N+ G A +P + ++ + P ++ ++ MI +R + Sbjct: 994 VTKLLEKLEYQFRVCAINKVGVGEHADVPGKVLVEDKLEAPDFELDADMRKMINIRAAST 1053 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L V G P P I W K + +K +++ +++ D G YTL AEN+ Sbjct: 1054 LRLFVPVRGRPTPEIKWGKADGEIKETAQVDVTGSYASLVIENVDRFDSGKYTLTAENAS 1113 Query: 812 GIAETSAVITV 822 G SA I+V Sbjct: 1114 G--TKSAFISV 1122 Score = 39.9 bits (89), Expect = 0.75 Identities = 21/77 (27%), Positives = 35/77 (45%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ V+ P P +W+ +K S D + + LVIR+ D G +T Sbjct: 8311 GKPIELRIPVKAKPLPVCSWYFGGVKLKDSLDRIKIDSNGKYSHLVIRDTTINDTGDYTL 8370 Query: 584 VAKNAAGFASSTTELIV 600 KNA G A+ ++I+ Sbjct: 8371 EVKNAVGMATELIKVII 8387 Score = 39.5 bits (88), Expect = 0.99 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + E +G PRP I+W + +K S+ + + DN + +R E AG +T Sbjct: 6246 GQNIHIELPFKGKPRPVISWLKDNLPLKESEKIR-FRTTDNKTAVTVRGAKKEHAGQYTL 6304 Query: 584 VAKN 587 V N Sbjct: 6305 VLDN 6308 Score = 39.1 bits (87), Expect = 1.3 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR---FQEITVKEKGTIKLVARVTRN 859 + + A+N+ G + T ++ +PP + Q + VK T L A V Sbjct: 2267 FRIIAKNAAGAISKPSESTGSITAKDEVDPPKYETDPMYNQMLVVKAGETFNLEATVEGK 2326 Query: 860 PVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P+P+ W++ + E+ + + +N D + L++ +D G Y V +N AG S Sbjct: 2327 PIPTAQWFKGDVEVENSARAEIKNTDFK--ALLVVKDAVRVDGGQYTLVLNNVAGTKS 2382 Score = 39.1 bits (87), Expect = 1.3 Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GST++ E + G P P+++ + +K + F D++ +++RE D+G + Sbjct: 5161 GSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSI-KIILRESVAGDSGRYDI 5219 Query: 584 VAKNAAGFASSTTELIV-EAPLSDHG 608 A N++G + S ++V + P + G Sbjct: 5220 TASNSSGTSKSFLNIVVLDRPSAPQG 5245 Score = 39.1 bits (87), Expect = 1.3 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 17/130 (13%) Query: 697 ITNVKKFQEGTYTVVAVNREG------EASLPIVLKIKTGEKEPPQVIEPLK----SMIV 746 +T + + + Y V+A N G E+S P+ K E PP+ K ++ + Sbjct: 7561 VTGLSEEETYEYHVIAKNAAGVHSAASESSGPVTCK---DEYSPPRAELDSKLVGETVTI 7617 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVY 803 G ++L V G P PT+ W K +K + L K + T ++ ++K D G Y Sbjct: 7618 SAGSDLVLDGAVGGKPEPTVYWSKGDK-ILELGEKYSLTYTATRAMAVIKNCDRSDTGRY 7676 Query: 804 TLKAENSEGI 813 L +N+ G+ Sbjct: 7677 CLTVKNASGV 7686 Score = 38.7 bits (86), Expect = 1.7 Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 4/113 (3%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGT-IKLVARVTRNPVPS 863 A+NS + + T +++ +PP I ++ +++ V G I+L A +T P+P Sbjct: 4425 AKNSAELLSAPSESTGPVTVKDDVDPPTIILEDKLRQLVVIRAGELIRLDAEITGRPLPV 4484 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 ++W ++ + I N L++ + DSG Y N AG S Sbjct: 4485 VSWSKDGKEIEAKARCEITSTNFNTTLIVRDAIRR-DSGQYVLTLHNVAGTRS 4536 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 5/120 (4%) Query: 708 YTVVAVNREG--EASLPI--VLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNP 762 + V A+N +G E S P V ++ E ++ + LK + +R G ++ L V G P Sbjct: 7973 FRVAALNSKGTGEFSDPSSEVEPLERTEMPDLELADDLKKTVCLRAGGTLRLMVFVTGRP 8032 Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 P + W K +++ D+++ +++ D G Y ++AEN G + ++ V Sbjct: 8033 TPVVAWRKTGVELQSRGYIETTDSYTCLMVEKVSRYDSGKYVVEAENPSGKKTATILVKV 8092 Score = 38.3 bits (85), Expect = 2.3 Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T E + G P P + W ++ I + ++ + D VA ++++E D G + Sbjct: 650 GETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIK-NTDFVARIIVKEAIRVDGGQYIL 708 Query: 584 VAKNAAGFASSTTELIV 600 + KN G S T + V Sbjct: 709 LVKNVGGEKSVTINVKV 725 Score = 38.3 bits (85), Expect = 2.3 Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 4/80 (5%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 ST++ V G P P+I W + IK + + + A+LVI V D+G +T Sbjct: 1052 STLRLFVPVRGRPTPEIKWGKADGEIKETAQVDV---TGSYASLVIENVDRFDSGKYTLT 1108 Query: 585 AKNAAGFASSTTEL-IVEAP 603 A+NA+G S+ + ++++P Sbjct: 1109 AENASGTKSAFISVRVLDSP 1128 Score = 38.3 bits (85), Expect = 2.3 Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S V+ + + P P I WF+ +KPS + ++ ++ +R+ ++G++ Sbjct: 5558 SDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFES-TSVFLRDTTRLNSGSYEVK 5616 Query: 585 AKNAAGFASSTTELIVE 601 KN+ G A +T +L+++ Sbjct: 5617 VKNSLGSACATVKLLIQ 5633 Score = 37.9 bits (84), Expect = 3.0 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 5/127 (3%) Query: 704 QEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGN 761 +E + V+AVN +G++ P++ + + +I L + V+ G+ + + G Sbjct: 4026 EEYAFRVIAVNDKGKSDAKPLISPVVVKDITVEPIINLLFDTYSVKAGDDLKIDVPFKGR 4085 Query: 762 PRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGI-AETSA 818 P+P ++W K+ + +K + + S ++K D G Y + +S G + A Sbjct: 4086 PQPEVSWKKDGQLLKQTTRVNVLTSKSSSKIVIKDATKDDTGKYEITLTSSVGTKSAVIA 4145 Query: 819 VITVEEP 825 VI +++P Sbjct: 4146 VIILDKP 4152 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 3/99 (3%) Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVK 798 P ++ VR G ++ ++G P P ++ K+N +K+ + ++ SI I+ + V Sbjct: 5152 PHNTVYVRAGSTLKCEIPLMGRPLPKVSLSKDNLQLKSTMRFNAEVTPDSIKIILRESVA 5211 Query: 799 -DEGVYTLKAENSEGIAETSA-VITVEEPTEENAEPPLF 835 D G Y + A NS G +++ ++ ++ P+ LF Sbjct: 5212 GDSGRYDITASNSSGTSKSFLNIVVLDRPSAPQGPVELF 5250 Score = 37.1 bits (82), Expect = 5.3 Identities = 16/83 (19%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 E+ + + ++L + P P+I W+++ + + PS ++ E+ + + + + ++ Sbjct: 5551 EVKFRAESDVELKFNIIAKPAPTIEWFKDGKELKPSVQLSFKHTFESTSVFLRDT-TRLN 5609 Query: 901 SGDYKCVASNSAGKSSHGARVTI 923 SG Y+ NS G + ++ I Sbjct: 5610 SGSYEVKVKNSLGSACATVKLLI 5632 Score = 36.7 bits (81), Expect = 7.0 Identities = 26/112 (23%), Positives = 51/112 (45%), Gaps = 5/112 (4%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRF--QEITVKEKGTIKLVARVTRNPVPSI 864 A N G+ E + V V +P ++ P + ++ + I V+ G++++ P P I Sbjct: 2662 AINKLGVGEPTEVPGVVKPIDKIEPPEVILDSDLRKGIVVRAGGSMRICIPFKGRPTPEI 2721 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 W + + + P + + GE+ + ++ + D+G Y NSAG S Sbjct: 2722 RWAKEDAEL-PGKVQVET--GEDYSQLSIDICDKYDAGKYILTLENSAGTKS 2770 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 731 EKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787 E +PP++ K +++V GE+ L A + G P P++ W K + + +T Sbjct: 629 EVDPPKIDLEAKYSQAVVVNAGETFTLEAAIYGKPLPSVHWLKEGQEITEAARLEIKNTD 688 Query: 788 SIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 + I+K D G Y L +N G E S I V+ Sbjct: 689 FVARIIVKEAIRVDGGQYILLVKNVGG--EKSVTINVK 724 Score = 36.3 bits (80), Expect = 9.2 Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 700 VKKFQEGTY---TVVAVNREGEAS-----LPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 V + GTY V AVN +G+ P+ K E + ++ R G Sbjct: 5897 VSHLKPGTYYFFKVSAVNCKGKGEDIKMYQPVQAKDILEEADLDLDVQMTTQYTARAGRD 5956 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT-HSITILKPKKVKDE-GVYTLKAEN 809 V + + G P P +TW + ++ + A + T + T++ PK +D+ G Y L+ EN Sbjct: 5957 VEIFIPLKGRPAPNVTWRRGDRNMAADNRYTISSTERATTLVIPKVTRDDCGKYLLEIEN 6016 Query: 810 SEG 812 G Sbjct: 6017 GVG 6019 >UniRef50_Q96RW7 Cluster: Hemicentin-1 precursor; n=40; Eumetazoa|Rep: Hemicentin-1 precursor - Homo sapiens (Human) Length = 5635 Score = 235 bits (574), Expect = 1e-59 Identities = 291/1201 (24%), Positives = 482/1201 (40%), Gaps = 129/1201 (10%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ EC+V+G P P +TW + + ++ ++ D+ ++ L ++ + D G + C Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI--LQLKNIHVSDTGRYVC 2363 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VA N AG +L V AP S G+ + P S Sbjct: 2364 VAVNVAGMTDKKYDLSVHAPPSIIGNHRS--------------------PENIS------ 2397 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V E + + L C IP P I W FK V N SV I S M L++ Sbjct: 2398 -VVEKNSVSLTCEASGIPLPSITW-FKDGWPVSLSN-SVRILSGGRM----LRLMQTTME 2450 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGN 761 G YT V N GE L + PP ++ L+ + V++ +SV L+ +V GN Sbjct: 2451 DAGQYTCVVRNAAGEERKIFGLSVLV----PPHIVGENTLEDVKVKEKQSVTLTCEVTGN 2506 Query: 762 PRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P P ITW K+ +P+ +A S G IT + +V G YT A + G S Sbjct: 2507 PVPEITWHKDGQPLQEDEAHHIISGGRFLQITNV---QVPHTGRYTCLASSPAGHKSRSF 2563 Query: 819 VITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 + V PT +++TV LV P +ITW+++ + + Sbjct: 2564 SLNVFVSPTIAGVGSD---GNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNR 2620 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL--- 934 I G ++++ D ++G Y CVA+N AG+ V + + + L Sbjct: 2621 NIRILPGGRTLQILNAQED---NAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGP 2677 Query: 935 ---QKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 K + + T+ LEC+ + S WY + + + DH I G Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEA 2735 Query: 990 XXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRKLQDF--------EVKEKDVAI---- 1035 D G C+ + E V +P +KL + + KDV I Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795 Query: 1036 -LEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 L E N + + W +DG + +K G R L I V D G Y+C+ + Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPL-TSSDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVN 2852 Query: 1094 ES--CTAEVTVVELPPEII----TRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSE 1145 E+ + + V L P II + L + NK+ L+ G R W KDG Sbjct: 2853 EAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQP 2912 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201 + +H + +G+ L+I + + D G Y C G++K L V P + Sbjct: 2913 LLEDDHHKFLSNGR--ILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPK 2970 Query: 1202 LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 E + V N LT E+ D++W K + I+ ++ RTL I + Sbjct: 2971 -SENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPG--GRTLQIIRAKV 3027 Query: 1261 DDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE----YRIKRGSDVTLLVDYQAFP 1315 D EYTC+ ++ +K K + V PP I D++ E ++ G+ V+L + A P Sbjct: 3028 SDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVP 3087 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P W N ++I + H + D + L IKK E +D G Y R N G D ++ Sbjct: 3088 PPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHL 3145 Query: 1376 TILDKPS--PPGKPNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKN 1432 + PS P + I+E S+ + + D TG I ++ ++ I+ ++ + V+ Sbjct: 3146 NVYVPPSIEGPEREVIVETISNPVTLTCDA---TGIPPPTIAWLKNHKRIENSDSLEVRI 3202 Query: 1433 IT-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 ++ ++ I + + S + A N + +YY + + E P ++ Sbjct: 3203 LSGGSKLQIARSQHSDSGNYTCIASNM-----EGKAQKYYFLSIQVPPSVAGAEIP-SDV 3256 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXX 1547 + E++EL C G+P P + W +DGK + + + N Sbjct: 3257 SVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGK 3316 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIW 1606 Y C+A N GE + + + P I + ++ ++ + D + + G PPP++ W Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 KNG L + + VIRI + S + YT ASN AG + L+V+ P Sbjct: 3377 LKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434 Query: 1667 S 1667 + Sbjct: 3435 N 3435 Score = 215 bits (525), Expect = 1e-53 Identities = 273/1202 (22%), Positives = 469/1202 (39%), Gaps = 101/1202 (8%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 K TS + P + T +G V C+ G P+P + W ++ +I S Sbjct: 971 KTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAK 1027 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619 + +L + E++G + C A N AG+A +L V G + + Sbjct: 1028 FSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS----- 1082 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 KP V G ++ L C + ++P P I W + + I P Sbjct: 1083 -----------------QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSP 1125 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE 739 + S +KIT + G Y VA N G + + L + PP++ Sbjct: 1126 RHTFLPS------GSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHV----PPKIQR 1175 Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799 K + V+ G+ V + G P P ITW K + + + D Sbjct: 1176 GPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSD 1235 Query: 800 EGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 G+YT A N G ET + V+E PT E+ EPP + FQE ++ A+ T Sbjct: 1236 AGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP-YNTTFQERVANQRIEFPCPAKGT- 1293 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P+I W N ++ E + + LVI +V + D+G+Y CVA N AG + Sbjct: 1294 -PKPTIKWLHNGRELTGREPGISILEDGTL-LVIASV-TPYDNGEYICVAVNEAGTTERK 1350 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREII 976 + + V V K + + L C+ T S WY + +++ + + Sbjct: 1351 YNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTV 1410 Query: 977 QEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTM-----LVVKETIPEFIRKLQDFEVKE 1030 G+ D G C + TS ++V TI + V Sbjct: 1411 NNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLN 1468 Query: 1031 KDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 +DVA LE ++ + D+ W +DG+ + + RG + L+++N +D+G Y C Sbjct: 1469 RDVA-LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRYQC 1525 Query: 1090 ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDG 1143 + + + + + +PP I ++ + ++E T+G + + W+KDG Sbjct: 1526 TVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDG 1585 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203 I S+ L ID K Q L I + D+ Y+C V N TA E S + + +P Sbjct: 1586 QPIMSSSQ-ALYID-KGQYLHIPRAQVSDSATYTCHVANVAGTA-----EKSFHVDVYVP 1638 Query: 1204 EFI----LVPANTDAY----LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 I P N LT+E + + +TW K ++ + + + KK Sbjct: 1639 PMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK-- 1696 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV--DYEREYRIKRGSDVTLLV 1309 L I E D+ +Y CV ++K EV V PP I D + + + + L Sbjct: 1697 LEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC 1756 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 P P W+ + ++I + K ++ + + +V NT G+Y+ N G Sbjct: 1757 HVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNT--GLYRCMAANTAGDH 1814 Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 E VT+ P+ + + N + I ++ + Q ++T + Sbjct: 1815 KKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQ--- 1871 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 N+ K Q+S + L+ + A V + A ET ++ ++ + P++E K Sbjct: 1872 -GNL-KIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH---EPPSLEDAGK 1926 Query: 1490 --NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENR-XXXXXXXXXXXXX 1545 N T + ++L C G P P +TWY+D + L + T+ NR Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDA 1986 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 YKC+A N G E + + P I+ SN + V + + GIP P + Sbjct: 1987 GIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV--VVNNPVRLECEARGIPAPSLT 2044 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W K+G+ + + + ++ + + S + +YT A N AG ++ L+VY Sbjct: 2045 WLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103 Query: 1666 PS 1667 P+ Sbjct: 2104 PN 2105 Score = 209 bits (511), Expect = 6e-52 Identities = 270/1179 (22%), Positives = 456/1179 (38%), Gaps = 93/1179 (7%) Query: 518 PKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575 PKH G V C +G P P ITW + + + + + D TL I + P Sbjct: 1177 PKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATP 1233 Query: 576 EDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT 635 DAG +TCVA N AG + L V+ P TV D+ T Sbjct: 1234 SDAGIYTCVATNIAGTDETEITLHVQEP-------PTVE------------DLEPPYNTT 1274 Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F ++ Q ++ C P+P I WL G E+ E ++I D ++L Sbjct: 1275 FQERVANQRIE------FPCPAKGTPKPTIKWLHNGRELTGREP-GISILEDG----TLL 1323 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVI 753 I +V + G Y VAVN G LK+ PP + E + ++ V + Sbjct: 1324 VIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV----PPVIKDKEQVTNVSVLLNQLTN 1379 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L +V G P P I W K+N V T + I L +D G Y+ KA N G Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439 Query: 814 AETSAVITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 ++ I V P P + F E++V + L +V P P I W+++ + Sbjct: 1440 SQKYFNIDVLVP------PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKP 1493 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + + + D + L + N D G Y+C SN+AGK + ++TI + Sbjct: 1494 LFLGDPNVELLDRGQV-LHLKNARRN-DKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551 Query: 933 HLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 ++ + LEC+T + WY + + I I +G+ Sbjct: 1552 NVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVS 1611 Query: 991 XXDVGVIKCIVKDQETST--MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD-- 1046 D C V + + V +P I + ++ V + + + A Sbjct: 1612 --DSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNP 1669 Query: 1047 ---VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102 + W +DG +K N E G +KL I + D G+Y C+ + E+ Sbjct: 1670 SPILTWLKDGVPVKANDN-IRIEAGG--KKLEIMSAQEIDRGQYICVATSVAGEKEIKYE 1726 Query: 1103 --VELPPEIITRLQNQK--VNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157 V +PP I + V N + +T + W KDG I + ++ ++ Sbjct: 1727 VDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN 1786 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTD 1213 G+K L I + + G Y C N+ K +TV P + L E ++V Sbjct: 1787 GRK--LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPV 1844 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 A + +TW K + +T + L R L I K +D YTCV +A Sbjct: 1845 ALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903 Query: 1274 KSTTKLKVEV-VEFPPKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 T+ +++ V PP + D + + + V L P P W +++++ Sbjct: 1904 AGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSG 1963 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 T + ++ + I+ + +DAGIYK N+ G ++ ++ + PS G N++ Sbjct: 1964 S--TSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMV 2021 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 + ++ E ++ + + + V + + ++ + + + + R Sbjct: 2022 AVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGR 2080 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 + AVN E + I P + +N++ ++ +EL C +P Sbjct: 2081 YTCVAVNAAG--------EKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPP 2132 Query: 1511 PKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 P +TW +DG L K + ENR Y C A N G+ E + V I Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 P I S+E + G+ + GIPPP +IW K G+ + D + Sbjct: 2193 VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR 2252 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 ++I ++S ++ Y+ ASN AGT+ E L+VY +P+ Sbjct: 2253 QLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPT 2291 Score = 200 bits (488), Expect = 3e-49 Identities = 249/1088 (22%), Positives = 430/1088 (39%), Gaps = 92/1088 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P+ S V + + LEC IP P + WL G + N + Sbjct: 2010 VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR--- 2066 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +L +T+ + G YT VAVN GE I L++ PP ++ +++ V ++ Sbjct: 2067 --ILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV----PPNIMGEEQNVSVLISQA 2120 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 V L Q P PT+TW K+ P+ P S + S+ ++ +V+D G YT +A N Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNN 870 G E + + + P L ++TV E I L+ + P P++ W + + Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDEL-----TQLTVIEGNLISLLCESSGIPPPNLIWKKKGS 2235 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKV 928 +++ S + G +L I ++ + D+ Y CVASN AG K + +V I Sbjct: 2236 PVLTDSMGRVRILSGGR-QLQI-SIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTIT 2293 Query: 929 TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 H + T GK++ LEC+ + W + + EI+ EG Sbjct: 2294 NSGSHPTEIIVT-RGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGH--ILQL 2350 Query: 987 XXXXXXDVGVIKCI------VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G C+ + D++ + +I R ++ V EK+ L E Sbjct: 2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEA 2410 Query: 1041 NS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESC 1096 + + W +DG + N G R L + T++ D G+Y+C++R+ E Sbjct: 2411 SGIPLPSITWFKDGWPVS-LSNSVRILSGG--RMLRLMQTTMEDAGQYTCVVRNAAGEER 2467 Query: 1097 TAEVTVVELPPEII--TRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQ 1153 V +PP I+ L++ KV + T E+T + W KDG +Q Sbjct: 2468 KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHH 2527 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSIN--FTLRLPEFI 1206 + G+ L+I + + G Y+C + S+ ++ P+I + PE + Sbjct: 2528 IISGGR--FLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDV 2585 Query: 1207 LVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 V N+ L E +TW+K + +E ++ RTL I ED+ Sbjct: 2586 TVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG--GRTLQILNAQEDNAGR 2643 Query: 1266 YTCVLLDAKSTTKLKVEVVEFPPKIVD---------YEREYRIKRGSDVTLLVDYQAFPQ 1316 Y+CV + EV + P I++ +E +IK + +TL + A P Sbjct: 2644 YSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPS 2703 Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 + W + + +K H +I + +L IK+ + +D G Y N G +++ +V Sbjct: 2704 ASLSWYKDGQPLKSDDHV--NIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVN 2761 Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENT--GNSTIIYYVVEYQEIDTTEWISVKN-I 1433 I PP + EI + E ++ N +Y T W + + Sbjct: 2762 I---QVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPL 2818 Query: 1434 TKTQ----------TSIQNLKTNSSYRFRAYAVNEVDISDASETTEY-YKVIKETKIQSP 1482 T + I K + R+ AVNE ++ +Y +V+ I+ Sbjct: 2819 TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA----GEDSLQYDVRVLVPPIIKGA 2874 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXX 1540 + P + +T N+ + C+ G P P+ +W +DG+ L N Sbjct: 2875 NSDLP-EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNT 2933 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y C+A N G + + + P VI +E++ V + +T + G Sbjct: 2934 QITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTV--VVNNFISLTCEVSGF 2991 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 PPP++ W KN ++ + I +T ++I K S +YT A N AG S + + Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVPGGRT--LQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049 Query: 1660 LKVYDKPS 1667 L VY PS Sbjct: 3050 LTVYVPPS 3057 Score = 197 bits (481), Expect = 2e-48 Identities = 269/1219 (22%), Positives = 480/1219 (39%), Gaps = 120/1219 (9%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S ++ EC+ G P P ITW++ I S +Y D + +V D+ T+TC Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKGQYLHIPRAQV--SDSATYTCH 1619 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 N AG A + + V P ++EG T P + Sbjct: 1620 VANVAGTAEKSFHVDVYVP-----------------------PMIEGNLAT----PLNKQ 1652 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V + LEC+ P P + WL G + ++NI + L+I + ++ Sbjct: 1653 VVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKK------LEIMSAQEID 1706 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNP 762 G Y VA + GE + K + PP + + IV + L V G+P Sbjct: 1707 RGQYICVATSVAGEKEI----KYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP 1762 Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 PTI W K+ + + ++ +V + G+Y A N+ G + +TV Sbjct: 1763 PPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQ 881 P P + + E V + + L P PSITW ++++ ++ ++ + Sbjct: 1823 HVP------PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKI 1876 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-ET 940 G +++ T ++ D+G Y CVA+N+AG++ + + V + ++ K ET Sbjct: 1877 QSSGRVLQIAKTLLE---DAGRYTCVATNAAGETQQ--HIQLHVHEPPSLEDAGKMLNET 1931 Query: 941 E-EGKTVILECQTS-HTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 V LEC+ + + V WY + + +SG + G+ D G+ Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS--DAGIY 1989 Query: 998 KCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG 1053 KC+ + +T L + P V + LE E A + W +DG Sbjct: 1990 KCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDG 2049 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110 + N G I L + + + D G Y+C+ + + + + V +PP I+ Sbjct: 2050 SPVSSFSNGLQVLSGGRI--LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIM 2107 Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 QN V L + DA+ + W KDG + L+I + LKI Sbjct: 2108 GEEQNVSVLISQAVEL---LCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLKIE 2162 Query: 1167 DCDLDDAGEYSCEVGN--SKCTAILTVE---EPSINFTLRLPEFILVPANTDAYLTVEIP 1221 D + D G Y+CE N K V P+I + L + ++ N + L Sbjct: 2163 DAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSG 2222 Query: 1222 DETLDVTWYKKKS-VIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 ++ W KK S V+ D+ + ++S R L I + D Y+CV + T K Sbjct: 2223 IPPPNLIWKKKGSPVLTDSMGRVRILSG--GRQLQISIAEKSDAALYSCVASNVAGTAKK 2280 Query: 1280 KVEV-VEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 + + V P I + + E + RG ++L + Q P P W+ + + K K + Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK----PNILE 1391 I + L +K + +D G Y N G D + ++++ PS G NI Sbjct: 2341 --ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISV 2398 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 ++ +S+++ E +I ++ + +S+ N + + + L+ + Sbjct: 2399 VEKNSVSLTC-EASGIPLPSITWFKDGWP-------VSLSNSVRILSGGRMLRLMQTTME 2450 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGVP 1509 A V + A E K+ + + P + E L+++ + + + LTC G P Sbjct: 2451 DAGQYTCVVRNAAGEER---KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNP 2507 Query: 1510 QPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 P++TW++DG+ L+ +A + Y C+A + G S + + Sbjct: 2508 VPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567 Query: 1568 QQKPVIT-ISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTK 1624 P I + ++ + V + V E PP + W+K+G LE+++ I Sbjct: 2568 FVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG 2627 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 +T ++I + ++ +Y+ A+N AG +KVY P +G + +S + V Sbjct: 2628 GRT--LQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVK 2685 Query: 1685 IEWKPPLDDGGLELTKYAI 1703 I+ L LE YAI Sbjct: 2686 IKVNNTLT---LECEAYAI 2701 Score = 196 bits (477), Expect = 7e-48 Identities = 270/1212 (22%), Positives = 474/1212 (39%), Gaps = 118/1212 (9%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM-YYDDDNVATL 568 P+F+++ GS V C V+GYP P I W R + S+ F + L Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I ++ D GT+ C A+N G S T + V ++ Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP---------------------- 890 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESD 687 L GI P+ + V EG + L C L+A P P+ W+ ++ + I+V + Sbjct: 891 LIGISPSVAN------VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS 944 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMI 745 +H I V+ G YT VA N G + +V+ + + Q++ + Sbjct: 945 LH-------IERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTI---- 993 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804 +G V L + GNP+P++ W K + + K S G S+ ++ P ++ G Y Sbjct: 994 --EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG-EESGEYV 1050 Query: 805 LKAENSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 A N+ G A+ +TV P + L ++ EI+V + L V P P Sbjct: 1051 CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPI 1110 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ITW + ++ISP ++++ T DSG Y CVA+N AG + ++ + Sbjct: 1111 ITWAKETQLISPFSPRHTFLPSGSMKITETRTS---DSGMYLCVATNIAGNVTQAVKLNV 1167 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXX 983 V ++ K + + G+ V + C T +K + + E Sbjct: 1168 HVPPK--IQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT 1225 Query: 984 XXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQD--FEVKEKDVAILE 1037 D G+ C+ + ET L V+E P + L+ ++ VA Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQE--PPTVEDLEPPYNTTFQERVANQR 1283 Query: 1038 VEI-----NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 +E + + W +G + ++ + G + L I + + +D GEY C+ Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL--LVIASVTPYDNGEYICVAV 1341 Query: 1093 DESCTAEVTV---VELPPEIITRLQNQKV----NKGNKATFEIELTKGDALVRWFKDGSE 1145 +E+ T E V +PP I + Q V N+ E+E T ++ W+KD + Sbjct: 1342 NEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP-SPIIMWYKDNVQ 1400 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLR 1201 + S+ IQ +GK LK++ +DAG YSC+ G S+ + V P Sbjct: 1401 VTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTN 1458 Query: 1202 LPEFILVPANTDAYLTVEIPDETL-DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCT 1259 P + V N D L ++ D+ W+K K + L+ + + L ++ Sbjct: 1459 FPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLD--RGQVLHLKNAR 1516 Query: 1260 EDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFP 1315 +D+ Y C + +A K +K+ + PP I + + + S + L + + P Sbjct: 1517 RNDKGRYQCTVSNAAGKQAKDIKL-TIYIPPSIKGGNVTTDISVLINSLIKLECETRGLP 1575 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P W + + I ID K L I + + +D+ Y + N G A+ +V Sbjct: 1576 MPAITWYKDGQPIMSSSQAL-YID-KGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHV 1633 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWD---EPENTGN-STIIYYVVEYQEIDTTEWISVK 1431 + P G N+ + + I E + GN S I+ ++ + + + Sbjct: 1634 DVYVPPMIEG--NLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKAND----- 1686 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE--KPLK 1489 NI + + + L+ S+ V S A E Y+V + P +E Sbjct: 1687 NI-RIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEV---DVLVPPAIEGGDETS 1742 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXX 1547 N +EL C G P P + W +DG+ + + N Sbjct: 1743 YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGL 1802 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C+A N G+ + V + P I S +E + K+K + + GIP P + Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYK---PVALQCIANGIPNPSIT 1859 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W K+ + N + N+ + V++I + + +YT A+N AG + + L V++ Sbjct: 1860 WLKDDQPV-NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEP 1918 Query: 1666 PSKPEGPVIMRE 1677 PS + ++ E Sbjct: 1919 PSLEDAGKMLNE 1930 Score = 193 bits (470), Expect = 5e-47 Identities = 242/1089 (22%), Positives = 423/1089 (38%), Gaps = 92/1089 (8%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L C + P I W G + + NI + L+I N ++ G Y+ VA Sbjct: 2595 LVCEAYSYPPATITWFKDGTPLESNRNIRILPGG------RTLQILNAQEDNAGRYSCVA 2648 Query: 713 VNREGEASLPIVLK------IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 N GE +K I G+ P + P K + ++ ++ L + P ++ Sbjct: 2649 TNEAGEMIKHYEVKVYIPPIINKGDLWGPG-LSP-KEVKIKVNNTLTLECEAYAIPSASL 2706 Query: 767 TWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 +W K+ +P+K+ + H++ I K ++ D G YT A N G E + ++ P Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQI-KEAQISDTGRYTCVASNIAGEDELDFDVNIQVP 2765 Query: 826 T--EENAEPPLFINRFQEITVKE---KGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 ++ E ++ + K+ I L P P++TWY++ ++ S+ + Sbjct: 2766 PSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVL 2825 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQKSY 938 G +++ V+ D+G Y CVA N AG+ S + RV + L + Sbjct: 2826 ILPGGRVLQIPRAKVE---DAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEV 2882 Query: 939 ETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 K+ ++EC +S + + + W + + + DH + + GR D+G Sbjct: 2883 TVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQIT--DIGR 2940 Query: 997 IKCIVKDQETSTMLVVKETI---PEFIR-KLQDFEVKEKDVAILEVEINS-ETADVVWER 1051 C+ ++ S + P I K ++ V + L E++ D+ W + Sbjct: 2941 YVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLK 3000 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPE 1108 + + IK N G R L I V D GEY+CI +++ ++ V +PP Sbjct: 3001 NEQPIKLNTNTL-IVPGG--RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPS 3057 Query: 1109 IITR----LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 I L V +G + E E ++ W+K+G I S H+++ DG Q L Sbjct: 3058 IKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QML 3115 Query: 1164 KIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 I ++ D G+Y C N K + PSI R E I+ + LT Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTC 3173 Query: 1219 E---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 + IP T + W K IE+++ + L I + D YTC+ + + Sbjct: 3174 DATGIPPPT--IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231 Query: 1276 TT-KLKVEVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 K ++ PP + E + + G +V L+ + P P +W+ + K I + Sbjct: 3232 KAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGE 3291 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN---- 1388 + + + ++L I +D G Y N G D N+ + P+ G + Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 ++ + +SINI E TG W+ + I+ L Sbjct: 3352 LMTLVDTSINI---ECRATGTPP-----------PQINWLKNGLPLPLSSHIRLLAAGQV 3397 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPL--KNITTEPNEDIELTC 1503 R V++V + + K +Q P ++ + + IT + C Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457 Query: 1504 IFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVET 1561 I G P P + W RDG+ L A T Y CIA N+ GEV Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSK 3517 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 ++ + + P I S E + V + +T + GIP P++ W K+G L + + Sbjct: 3518 HFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQ--V 3575 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP--SKPEGPVIMREIS 1679 T V+RI + + +YT AS+ AG E ++V+ P + + P + + Sbjct: 3576 QTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLR 3635 Query: 1680 RESVTIEWK 1688 VT+E K Sbjct: 3636 NRQVTLECK 3644 Score = 184 bits (449), Expect = 2e-44 Identities = 262/1206 (21%), Positives = 456/1206 (37%), Gaps = 135/1206 (11%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G+ + C+ G P P + W ++ + ++ S + I E DA + Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE--KSDAALY 2267 Query: 582 TCVAKNAAGFASS--TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 +CVA N AG A ++ + +++ GS T ++ +GIPP Sbjct: 2268 SCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEV-QGIPP----- 2321 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P ++ +G ++ KG EI+ DE +L++ N Sbjct: 2322 PTVTWMKDGHPLIKA---------------KGVEIL-DEG-------------HILQLKN 2352 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS---MIVRQGESVILSA 756 + G Y VAVN G L + PP +I +S + V + SV L+ Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTC 2408 Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 + G P P+ITW K+ PV + + L ++D G YT N+ G Sbjct: 2409 EASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 ++V P E N +++ VKEK ++ L VT NPVP ITW+++ + + Sbjct: 2469 IFGLSVLVPPHIVGE-----NTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQED 2523 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 E G ++ ITNV +G Y C+AS+ AG S + + V + + Sbjct: 2524 EAHHIISGGRFLQ--ITNVQVP-HTGRYTCLASSPAGHKSRSFSLNVFVSPT--IAGVGS 2578 Query: 937 SYETEEGKTVILECQTS--------HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 E+ TVIL TS + W+ + + + I+ GR Sbjct: 2579 DGNPED-VTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILN 2635 Query: 989 XXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK-------LQDFEVKEK--DVAILE 1037 + G C+ ++ E VK IP I K L EVK K + LE Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695 Query: 1038 VEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 E + +A + W +DG+ +K + + GH L I+ + D G Y+C+ + + Sbjct: 2696 CEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAG 2752 Query: 1097 TAEVTV---VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDAL-----------VRWF 1140 E+ +++PP + + N N ++ + +L + W+ Sbjct: 2753 EDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWY 2812 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196 KDG + S+ + + G+ L+I ++DAG Y+C E G + V P I Sbjct: 2813 KDGHPLTSSDKVLILPGGR--VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPI 2870 Query: 1197 --NFTLRLPEFILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 LPE + V N A + + +W K + + + +S+ R L Sbjct: 2871 IKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSN--GRIL 2928 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDY 1311 I D Y CV + + K + V PP ++ + E + + ++L + Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEV 2988 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 FP P+ W+ N + IK +T I +L I + + +D G Y N G + Sbjct: 2989 SGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKK 3046 Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWIS 1429 + ++T+ PS I + DS S+++ N T + E + W Sbjct: 3047 KFSLTVYVPPS------IKDHDSESLSVV-----NVREGTSVSLECESNAVPPPVITWYK 3095 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEK 1486 + T ++ L + V++ + K + P++E Sbjct: 3096 NGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 3155 Query: 1487 PLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXX 1541 P + + E + + LTC G+P P + W ++ K+++ + + Sbjct: 3156 PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y CIA N G+ + + IQ P + + +G+ + GIP Sbjct: 3216 HSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT 3275 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P + W K+G + + + I S + I S + KYT A+N AG L Sbjct: 3276 PLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLN 3335 Query: 1662 VYDKPS 1667 VY P+ Sbjct: 3336 VYVTPT 3341 Score = 180 bits (439), Expect = 3e-43 Identities = 241/1193 (20%), Positives = 429/1193 (35%), Gaps = 91/1193 (7%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 +T+ EC+ P ++W++ +K + N TL I+E D G +TCV Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAA---NGHTLQIKEAQISDTGRYTCV 2746 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 A N AG ++ ++ P S ++L+ + +A+ Sbjct: 2747 ASNIAGEDELDFDVNIQVPPS-------------FQKLWEIGNMLDT-----GRNGEAKD 2788 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V + I L C A P P + W G + + + + VL+I K Sbjct: 2789 VIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGG------RVLQIPRAKVED 2842 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G YT VAVN GE SL +++ + + + V +S ++ G+P P Sbjct: 2843 AGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAP 2902 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +W K+ +P+ I + ++ D G Y AEN+ G A+ + V Sbjct: 2903 RNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P P + + + +TV I L V+ P P ++W +N + I + Sbjct: 2963 P------PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPG 3016 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET---E 941 G ++++ V D G+Y C+A N AG+S +T+ V + H +S Sbjct: 3017 GRTLQIIRAKVS---DGGEYTCIAINQAGESKKKFSLTVYVPP-SIKDHDSESLSVVNVR 3072 Query: 942 EGKTVILECQTSHTVST--KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 EG +V LEC+++ WY N + I+ H EI+ +G+ V + Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRA 3132 Query: 1000 IV---KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 I +D + + V E + E V + + W ++ + I Sbjct: 3133 INVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRI 3192 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRL 1113 + + + KL I + D G Y+CI + A+ +++PP + Sbjct: 3193 E-NSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAE 3251 Query: 1114 QNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 V+ E+ L++W KDG I ++ + L IY Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALT 3311 Query: 1171 DDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 D G+Y+C N + + P+I E ++ +T + Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPP 3371 Query: 1226 -DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 + W K + + L++ + + I + D YTCV + + Sbjct: 3372 PQINWLKNGLPLPLSSHIRLLA--AGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429 Query: 1285 EFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 F P +D E + +GS ++ P P+ W+ + + + H ++ + Sbjct: 3430 VFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHL--TVSTH 3487 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 L + K E D+G Y N G + +L+ P G EI S +N Sbjct: 3488 GMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEI-SVIVN--- 3543 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD- 1460 N T I + ++ W+ +Q L R V + Sbjct: 3544 ----NPLELTCIASGIPAPKMT---WMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGR 3596 Query: 1461 -----ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 S A + + Y V ++P ++IT N + L C VP P +TW Sbjct: 3597 YTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP-RDITVLRNRQVTLECKSDAVPPPVITW 3655 Query: 1516 YRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 R+G++L+ Y C+A N G+ ++ + P I Sbjct: 3656 LRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNI 3715 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRI 1632 + + + ++ + EG+P P + W K+G L N Y+I + + I Sbjct: 3716 KGGPQSLVIL--LNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSIL---ENGFLHI 3770 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 + + + +Y A+N AGT + L+V+ PS GP M I T+ Sbjct: 3771 QSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTL 3823 Score = 178 bits (434), Expect = 1e-42 Identities = 266/1185 (22%), Positives = 444/1185 (37%), Gaps = 112/1185 (9%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 ++ +C V G P P I W + +I F++ N LVI + + G + C+A Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILL---NGRKLVIAQAQVSNTGLYRCMAA 1808 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ-YV 645 N AG DH E V +PPT ++ V Sbjct: 1809 NTAG---------------DHKKEFEVTVH---------------VPPTIKSSGLSERVV 1838 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + + L+C IP P I WL K ++ V ++ I+S VL+I Sbjct: 1839 VKYKPVALQCIANGIPNPSITWL-KDDQPVNTAQGNLKIQSSGR----VLQIAKTLLEDA 1893 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGESVILSAQVVGNPR 763 G YT VA N GE I L + EPP + + K + V V L + GNP Sbjct: 1894 GRYTCVATNAAGETQQHIQLHVH----EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPV 1949 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P ITW K+N+ + + + + I ++ ++ D G+Y A NS G E + V Sbjct: 1950 PVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVH 2009 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P + V ++L P PS+TW ++ +S Q Sbjct: 2010 -------VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVL 2062 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 G I L +T+ D+G Y CVA N+AG+ + + V + S + Sbjct: 2063 SGGRI-LALTSAQIS-DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQA 2120 Query: 944 KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 ++ + + W + + I E R D G C + Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLS-ISENR-SVLKIEDAQVQDTGRYTCEATN 2178 Query: 1004 --QETSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE-II 1056 +T V +P I +L V E ++ L E + +++W++ G ++ Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVL 2238 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRL 1113 + G R+L I D YSC+ + + TA+ V + P I Sbjct: 2239 TDSMGRVRILSGG--RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSG 2296 Query: 1114 QNQK---VNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 + V +G + E E+ V W KDG + + +++ +G +LK + Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLK--NIH 2354 Query: 1170 LDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 + D G Y C N K + PSI R PE I V LT E Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIP 2414 Query: 1225 L-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVE 1282 L +TW+K + + ++S R L + + T +D +YTCV+ +A K+ Sbjct: 2415 LPSITWFKDGWPVSLSNSVRILSG--GRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGL 2472 Query: 1283 VVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V PP IV + ++K VTL + P P W + + ++ + I S Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQ--EDEAHHIIS 2530 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-----PPGKPNILEIDSS 1395 L I V+ G Y + GH ++ + P+ G P + + + Sbjct: 2531 GGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN 2590 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 S E + +TI ++ + +++ I + +T I N + +++ R+ A Sbjct: 2591 SPTSLVCEAYSYPPATITWF-KDGTPLESNRNIRILPGGRT-LQILNAQEDNAGRYSCVA 2648 Query: 1456 VNEV-DISDASETTEYY-KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 NE ++ E Y +I + + P + K + + N + L C +P + Sbjct: 2649 TNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSP--KEVKIKVNNTLTLECEAYAIPSASL 2706 Query: 1514 TWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 +WY+DG+ LK+ N Y C+A N GE E V IQ P Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766 Query: 1572 ----VITISNE-DIKQKHKVGDEWLVTAV-----IEGIPPPEVIWYKNGNKLENDKEYNI 1621 + I N D + + D + + PPP + WYK+G+ L + + I Sbjct: 2767 SFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI 2826 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + V++I K + +YT A N AG S++ ++V P Sbjct: 2827 LPGGR--VLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869 Score = 176 bits (429), Expect = 5e-42 Identities = 262/1150 (22%), Positives = 439/1150 (38%), Gaps = 122/1150 (10%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 + A +SD G T D+ +PP + + V + L C+ Sbjct: 2070 LTSAQISDTG-RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 AIP P + WL G ++ +S++ SVLKI + + G YT A N G+ Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISENR------SVLKIEDAQVQDTGRYTCEATNVAGK 2182 Query: 719 ASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 + I PP + + L + V +G + L + G P P + W K PV Sbjct: 2183 TEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVL 2238 Query: 777 A-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENA 830 + S G I+I + D +Y+ A N G A+ + V PT N+ Sbjct: 2239 TDSMGRVRILSGGRQLQISIAEK---SDAALYSCVASNVAGTAKKEYNLQVYIRPTITNS 2295 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 + EI V +I L V P P++TW ++ + ++ + +G ++L Sbjct: 2296 G-----SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQL 2350 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ-KSYETEEGKTVILE 949 +V D+G Y CVA N AG + +++ H ++ E +V L Sbjct: 2351 KNIHVS---DTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLT 2407 Query: 950 CQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--E 1005 C+ S S W+ + +S + I+ GR D G C+V++ E Sbjct: 2408 CEASGIPLPSITWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGE 2465 Query: 1006 TSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKN 1061 + + +P I L+D +VKEK L E+ + ++ W +DG+ ++ + Sbjct: 2466 ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQ-EDE 2524 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELP----------P 1107 + G R L I N V G Y+C+ +S + + V P P Sbjct: 2525 AHHIISGG--RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP 2582 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 E +T + N + +A + A + WFKDG+ ++ + +I++ G+ L+I + Sbjct: 2583 EDVTVILNSPTSLVCEA-----YSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILN 2635 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVE-----EPSIN----FTLRL-PEFILVPANTDAYLT 1217 D+AG YSC N I E P IN + L P+ + + N L Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695 Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 E IP +L +WYK ++ + + ++ TL I++ D YTCV + Sbjct: 2696 CEAYAIPSASL--SWYKDGQPLKSDDHVNIAAN--GHTLQIKEAQISDTGRYTCVASNIA 2751 Query: 1275 STTKLKVEV-VEFPP---------KIVDYEREYRIKR---GSDVTLLVDYQAFPQPNDEW 1321 +L +V ++ PP ++D R K + ++L + A P P W Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTW 2811 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + + K I L I + + DAG Y N G ++ +V +L P Sbjct: 2812 YKDGHPL--TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869 Query: 1382 SPPGKPNILE------IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 G + L ++ S++ C ++ E D +++S I + Sbjct: 2870 IIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQ 2929 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 I N + R+ A N A +Y+ + + + +N+T Sbjct: 2930 ----ILNTQITDIGRYVCVAEN-----TAGSAKKYFNL--NVHVPPSVIGPKSENLTVVV 2978 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 N I LTC G P P ++W ++ + KL T Y CIA Sbjct: 2979 NNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAI 3038 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611 N GE + + + P I + + V + V+ E +PPP + WYKNG Sbjct: 3039 NQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGR 3098 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS--KP 1669 + I + ++ IK+ + S + +Y A N AG L VY PS P Sbjct: 3099 MITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP 3156 Query: 1670 EGPVIMREIS 1679 E VI+ IS Sbjct: 3157 EREVIVETIS 3166 Score = 173 bits (422), Expect = 3e-41 Identities = 232/1115 (20%), Positives = 425/1115 (38%), Gaps = 83/1115 (7%) Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653 S L +E G E T ++ + PT + EG + L Sbjct: 941 SDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTL 1000 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 C+ P+P + W KGE ++ + + +D +Y + + + G Y A Sbjct: 1001 PCKASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLY-----VVSPGGEESGEYVCTAT 1054 Query: 714 NREGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 N G A + L + G++ +P++ ++ GE V L +V P P ITW Sbjct: 1055 NTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLA-GEEVTLPCEVKSLPPPIITW 1113 Query: 769 CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 K + + + + + D G+Y A N G + + V P + Sbjct: 1114 AKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKI 1173 Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGEN 887 P + ++ V ++ I A+ T P+P ITW + ++ E N DG Sbjct: 1174 QRGP-----KHLKVQVGQRVDIPCNAQGT--PLPVITWSKGGSTMLVDGEHHVSNPDGT- 1225 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-----E 942 L I D+G Y CVA+N AG +T+ V++ V+ L+ Y T Sbjct: 1226 --LSIDQATPS-DAGIYTCVATNIAGTDE--TEITLHVQEPPTVEDLEPPYNTTFQERVA 1280 Query: 943 GKTVILECQTSHTV--STKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKC 999 + + C T + KW HN +E++G + I+++G D G C Sbjct: 1281 NQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--TLLVIASVTPYDNGEYIC 1338 Query: 1000 IVKDQETST--MLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053 + ++ +T +K +P I+ ++ + V + L E+ + ++ W +D Sbjct: 1339 VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDN 1398 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110 + + + G I KL+ + D G YSC + + T++ V +PP II Sbjct: 1399 VQVT-ESSTIQTVNNGKILKLF--RATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTII 1455 Query: 1111 -TRLQNQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 T N+ V E ++ KG + WFKDG + F + + + Q L + Sbjct: 1456 GTNFPNEVSVVLNRDVALECQV-KGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLK 1513 Query: 1167 DCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 + +D G Y C V N+ LT+ P + I V N+ L E Sbjct: 1514 NARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRG 1573 Query: 1223 ETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 + +TWYK I + + I K + L I + D YTC + + T + Sbjct: 1574 LPMPAITWYKDGQPIMSSSQALYID--KGQYLHIPRAQVSDSATYTCHVANVAGTAEKSF 1631 Query: 1282 EVVEFPPKIVDYEREYRIKR----GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 V + P +++ + + +TL P P W+ + +K + + Sbjct: 1632 HVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR-- 1689 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 I++ L I + D G Y + G +++ V +L P+ G Sbjct: 1690 IEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVN 1749 Query: 1398 NICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 N+ + TG+ I ++ + Q ID + + + + I + +++ +R A Sbjct: 1750 NLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKIL-LNGRKLVIAQAQVSNTGLYRCMAA 1808 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTW 1515 N ++ K + T PT++ L + + L CI G+P P +TW Sbjct: 1809 NTAG--------DHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITW 1860 Query: 1516 YRDGKKLKTAKATYENRXX---XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +D + + TA+ + + Y C+A N GE + + + + P Sbjct: 1861 LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 + + + + + V + + G P P + WYK+ L ++T + +I I Sbjct: 1921 LEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRGQIIDI 1978 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + + S + Y A N+AG + + +L+V+ PS Sbjct: 1979 ESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS 2013 Score = 173 bits (421), Expect = 4e-41 Identities = 252/1208 (20%), Positives = 458/1208 (37%), Gaps = 111/1208 (9%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S C+ YP ITWF+ ++ +++ ++ TL I ++AG ++CV Sbjct: 2591 SPTSLVCEAYSYPPATITWFKDGTPLESNRNIRIL---PGGRTLQILNAQEDNAGRYSCV 2647 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 A N AG E+ V P + ++ P S PK Sbjct: 2648 ATNEAGEMIKHYEVKVYIPPIINKGDLW--------------------GPGLS--PKEVK 2685 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + + + LEC AIP ++W G+ + D+++++A L+I + Sbjct: 2686 IKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH------TLQIKEAQISD 2739 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIV--RQGES--------V 752 G YT VA N GE L + I+ PP Q + + +M+ R GE+ + Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQV----PPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 L + P PT+TW K+ P+ + + + KV+D G YT A N G Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855 Query: 813 IAETSAVITVEEPT---EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 + V P N++ P +E+TV + + + +P P +W ++ Sbjct: 2856 EDSLQYDVRVLVPPIIKGANSDLP------EEVTVLVNKSALIECLSSGSPAPRNSWQKD 2909 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + + +G ++++ T + D G Y CVA N+AG + + + V + Sbjct: 2910 GQPLLEDDHHKFLSNGRILQILNTQIT---DIGRYVCVAENTAGSAKKYFNLNVHVPP-S 2965 Query: 930 FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + ++ + L C+ S W N++ I + I+ GR Sbjct: 2966 VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRA 3025 Query: 988 XXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIR-----KLQDFEVKEKDVAILEVEI 1040 D G CI +Q E+ + +P I+ L V+E LE E Sbjct: 3026 KVS--DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECES 3083 Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 N+ V+ W ++G +I + E + L+I+ V D G+Y C + + + Sbjct: 3084 NAVPPPVITWYKNGRMITESTH---VEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD 3140 Query: 1100 VTV---VELPPEIITRLQNQKVNK-GNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQL 1154 V +PP I + V N T + T + W K+ I+ S+ +++ Sbjct: 3141 KNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEV 3200 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPA 1210 I KL+I D+G Y+C N + A L+++ P +P + V Sbjct: 3201 RILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLL 3260 Query: 1211 NTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 + L T + W K I E + TL I D +YTCV Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320 Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF--PQPNDEWIVNS 1325 + + + V P + + ++ D ++ ++ +A P P W+ N Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNG 3380 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP- 1384 + H + + + + I + + +D +Y N G + N+ + P+ Sbjct: 3381 LPLPLSSHIR--LLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDN 3438 Query: 1385 --GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 G I + SS ++ S + ++ + Q + ++V + Sbjct: 3439 SMGTEEITVLKGSSTSMACITDGTPAPS--MAWLRDGQPLGLDAHLTVSTHGMV-LQLLK 3495 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 +T S ++ A NE A E ++++ KV++ I + + I P +E Sbjct: 3496 AETEDSGKYTCIASNE-----AGEVSKHFILKVLEPPHINGSEEHEEISVIVNNP---LE 3547 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 LTCI G+P PK+TW +DG+ L T Y C+A + G+ Sbjct: 3548 LTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + +V + P I ++E + + + +PPP + W +NG +L+ Sbjct: 3608 DDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPR 3667 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 I + + ++I ++ YT ASN AG ++ E L V P+ GP + + Sbjct: 3668 VRILSGGR--YLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVIL 3725 Query: 1679 SRESVTIE 1686 +S +E Sbjct: 3726 LNKSTVLE 3733 Score = 165 bits (402), Expect = 9e-39 Identities = 238/1078 (22%), Positives = 414/1078 (38%), Gaps = 81/1078 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G PP F ++P ++ GS++ L C + PEP I W + + +P + ++ S + Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKW--RRLDNMPIFSRPFSVSSISQL 847 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L I N+ +GTY A N+ G+ + + TG P I P + ++ + Sbjct: 848 RTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV-TGLVAPLIGISPSVANVIEGQQ 906 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTLKA 807 + + GNP P W KN+ + P +SDG H ++ +++D G YT A Sbjct: 907 LTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLH----IERVQLQDGGEYTCVA 962 Query: 808 ENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G +T++V+ PT ++ + Q ++ E + L + + NP PS+ W Sbjct: 963 SNVAGTNNKTTSVVVHVLPTIQHGQ--------QILSTIEGIPVTLPCKASGNPKPSVIW 1014 Query: 867 YRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 + E+IS S + DG L + + E +SG+Y C A+N+AG + ++T+ V Sbjct: 1015 SKKGELISTSSAKFSAGADG---SLYVVSPGGE-ESGEYVCTATNTAGYAKRKVQLTVYV 1070 Query: 926 EKVTF--VKHLQKSYETE----EGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQ 977 F + L + E G+ V L C+ W + IS R Sbjct: 1071 RPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFL 1130 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVA 1034 D G+ C+ + + VK + P+ R + +V+ Sbjct: 1131 P--SGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRV 1188 Query: 1035 ILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 + V+ W + G + + G L I + D G Y+C+ + Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATPSDAGIYTCVATN 1245 Query: 1094 ESCTAEV----------TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDG 1143 + T E TV +L P T Q + N+ + + T ++W +G Sbjct: 1246 IAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTP-KPTIKWLHNG 1304 Query: 1144 SEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINF 1198 E+ I + DG L I D GEY C E G ++ L V P + Sbjct: 1305 RELTGREPGISILEDG--TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIK 1362 Query: 1199 TLRLPEFILVPAN--TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256 + V N T+ + VE + + WYK ++ TE T+ + + L + Sbjct: 1363 DKEQVTNVSVLLNQLTNLFCEVEGTPSPI-IMWYKDN--VQVTESSTIQTVNNGKILKLF 1419 Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV--DYEREYRIKRGSDVTLLVDYQA 1313 + T +D Y+C ++ T++ + V PP I+ ++ E + DV L + Sbjct: 1420 RATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKG 1479 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P+ W + K + +D + L +K D G Y+ + N G ++ Sbjct: 1480 TPFPDIHWFKDGKPLFLGDPNVELLD-RGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKN 1432 +TI PS G +I ++ E E G I + + Q I ++ Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALY 1596 Query: 1433 ITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 I K Q I + + S + + N ++ +E + + V I+ + PL N Sbjct: 1597 IDKGQYLHIPRAQVSDSATYTCHVAN---VAGTAEKSFHVDVYVPPMIEG-NLATPL-NK 1651 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYK 1549 + L C G P P +TW +DG +K Y Sbjct: 1652 QVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYI 1711 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 C+A + GE E V + P I +E V + + + G PPP ++W K+ Sbjct: 1712 CVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKD 1771 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 G ++ + I + V I + + S++ Y A+NTAG E + V+ P+ Sbjct: 1772 GQLIDERDGFKILLNGRKLV--IAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPT 1827 Score = 164 bits (399), Expect = 2e-38 Identities = 241/1072 (22%), Positives = 409/1072 (38%), Gaps = 79/1072 (7%) Query: 632 IPPTFS--KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PP+ + + P V G ++ L C IP P I WL G+ I E + + ++ Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG- 3301 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S L I G YT VA N GE L + E K M + Sbjct: 3302 ---STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD- 3357 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 S+ + + G P P I W KN P+ + + +V D VYT A N Sbjct: 3358 TSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G+ + V P N + + +EITV + + + P PS+ W R+ Sbjct: 3418 RAGVDNKHYNLQVFAPP--NMDNSMGT---EEITVLKGSSTSMACITDGTPAPSMAWLRD 3472 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + +T + G ++L+ + DSG Y C+ASN AG+ S + KV Sbjct: 3473 GQPLGLDAHLTVSTHGMVLQLLKAETE---DSGKYTCIASNEAGEVSKHF-----ILKVL 3524 Query: 930 FVKHLQKSYETEEGKTVI-----LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXX 982 H+ S E EE ++ L C S + K W + + + D + + G Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVL 3584 Query: 983 XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILE 1037 D G C+ + +V+ +P I + +D V LE Sbjct: 3585 RISTAQVE--DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE 3642 Query: 1038 VEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES- 1095 + ++ V+ W R+GE ++ + G R L I N + D Y+C+ + + Sbjct: 3643 CKSDAVPPPVITWLRNGERLQATP-RVRILSGG--RYLQINNADLGDTANYTCVASNIAG 3699 Query: 1096 -CTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNH 1151 T E + V +PP I Q+ + NK+T + +G R W KDG+ + NH Sbjct: 3700 KTTREFILTVNVPPNIKGGPQSLVILL-NKSTVLECIAEGVPTPRITWRKDGAVLA-GNH 3757 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPEFI 1206 + +I + L I + D G Y C N+ T ++ PSI P + Sbjct: 3758 ARYSIL-ENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSI---APGPTNM 3813 Query: 1207 LVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 V N L E IP +++ W K ++ + + +L+I + DD Sbjct: 3814 TVIVNVQTTLACEATGIPKPSIN--WRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDT 3871 Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 Y C + + K V++ V+ PP I D ++ + + + + P P+ W Sbjct: 3872 ATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 N I+ S ++ I + AG Y N G A + + + + P Sbjct: 3932 KNG--IRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPV 3989 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 +P+ L + ++ + E T + I + E I+V + + + Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPFITWQ---------KEGINVNTSGRNHAVLPS 4040 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIEL 1501 S R A + ++ T K+ + +Q P V P LK ++ I L Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGKI--KLNVQVPPVISPHLKEYVIAVDKPITL 4098 Query: 1502 TCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 +C G+P P +TW++DG+ + ++ + + Y C+A N G Sbjct: 4099 SCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSS 4158 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 TS + + P I S E ++ + ++ V +GIP P + W K+ L N Sbjct: 4159 TSTKLTVHVPPRIR-STEGHYTVNE-NSQAILPCVADGIPTPAINWKKDNVLLAN--LLG 4214 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 T E + ++ + S YT A+N AG + V+L V+ P+ E P Sbjct: 4215 KYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELP 4266 Score = 160 bits (389), Expect = 3e-37 Identities = 222/1029 (21%), Positives = 397/1029 (38%), Gaps = 84/1029 (8%) Query: 680 ISVAIESDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 +++ ++ + SV L I V EG Y +AV+ G + EPP VI Sbjct: 468 VTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS----EPPPVI 523 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV 797 + ++ V GE +L+ ++ +TW +N++ V+ A P + + LK K Sbjct: 524 QVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKF 583 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 D G Y + G + S +TV+EP + P + Q T + + ++ T Sbjct: 584 NDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMP-----KNQSFTGGSE--VSIMCSAT 636 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P I W N+ I S DG L I N + D+G Y C+ASNSAG Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSDG---TLFIKNAAPK-DAGIYGCLASNSAGTDKQ 692 Query: 918 GARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHRE 974 + + I+ K+ V Q G ++EC+TS KW+ E+ Sbjct: 693 NSTLRYIEAPKLMVV---QSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF-- 747 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEK 1031 +I + D G C+ ++ T + + + P FI++ D ++ Sbjct: 748 LIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIG 807 Query: 1032 DVAILEVEINSETADVV-WER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 L + + W R D I + + L+I N D+G Y C Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867 Query: 1090 ILRDE--SCTAEVTVVE---LPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKD 1142 ++ +E TV + P I V +G + T L G+ + RW K+ Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKN 927 Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-----NSKCTAILTVEEPSIN 1197 + + + +I + DG L I L D GEY+C N+K T+++ P+I Sbjct: 928 SAMLLQNPYITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQ 984 Query: 1198 FTLRLPEFIL-VPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLII 1255 ++ I +P + + V W KK +I + KF+ +D +L + Sbjct: 985 HGQQILSTIEGIPVTLPCKAS---GNPKPSVIWSKKGELISTSSAKFSAGAD---GSLYV 1038 Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER--------EYRIKRGSDVT 1306 ++ EY C + K KV++ V P++ +R E + G +VT Sbjct: 1039 VSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVT 1098 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 L + ++ P P W +++I + S S+ I + +D+G+Y N Sbjct: 1099 LPCEVKSLPPPIITWAKETQLISPFSPRHTFL--PSGSMKITETRTSDSGMYLCVATNIA 1156 Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426 G+ + + + P P L++ + D P N + + V+ + + +T Sbjct: 1157 GNVTQAVKLNVHVPPKIQRGPKHLKV---QVGQRVDIPCNAQGTPL--PVITWSKGGSTM 1211 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE- 1485 + ++ ++ + Y +I+ E TE ++E PTVE Sbjct: 1212 LVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE-TEITLHVQE----PPTVED 1266 Query: 1486 -KPLKNITTE---PNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXX 1538 +P N T + N+ IE C G P+P + W +G++L + + E+ Sbjct: 1267 LEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIA 1326 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C+A N+ G E + + PVI + + + +EG Sbjct: 1327 SVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEG 1386 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P P ++WYK + ++ + I T ++++ + +Y+ +A N AGTS Sbjct: 1387 TPSPIIMWYK--DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYF 1444 Query: 1659 TLKVYDKPS 1667 + V P+ Sbjct: 1445 NIDVLVPPT 1453 Score = 151 bits (367), Expect = 2e-34 Identities = 241/1167 (20%), Positives = 421/1167 (36%), Gaps = 118/1167 (10%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS+ C +G P P + W R + D + + L + + ED+G +TC Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPL--GLDAHLTVSTHGMV-LQLLKAETEDSGKYTC 3506 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A N AG S L V P +GSE I GIP PK Sbjct: 3507 IASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIP-----APKMT 3561 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 ++ +G +P+ D G E VL+I+ + Sbjct: 3562 WMKDGR---------PLPQTDQVQTLGGGE--------------------VLRISTAQVE 3592 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGESVILSAQVVG 760 G YT +A + G+ ++++ PP + EP + + V + V L + Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRVHV----PPNIAGTDEP-RDITVLRNRQVTLECKSDA 3647 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P P ITW +N + ++A P + + D YT A N G ++ Sbjct: 3648 VPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFIL 3707 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 TV P P + I + + ++ +A P P ITW ++ +++ + Sbjct: 3708 TVNVPPNIKGGPQSLV-----ILLNKSTVLECIAEGV--PTPRITWRKDGAVLAGNHARY 3760 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + + + +V D+G Y C+A+N+AG + + V + Sbjct: 3761 SILENGFLHIQSAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIV 3817 Query: 941 EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 T+ E S W N ++ ++ + D +C Sbjct: 3818 NVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECT 3877 Query: 1001 VKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEII 1056 V + + T+ + + P + DF V + A++ + + W ++G + Sbjct: 3878 VTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRL 3937 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA--EVTV-VELPPEIITRL 1113 P+ + Y G I I T ++ G Y+C+ R+ + +A VT+ V PP I + Sbjct: 3938 LPRGDGYRILSSGAIE---ILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQP 3994 Query: 1114 QNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS--NHIQLTIDGKKQKLKIYDCDL 1170 V N E T + W K+G + S NH L G L+I Sbjct: 3995 SELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG----LQISRAVR 4050 Query: 1171 DDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL- 1225 +DAG Y C N TA+ L V+ P + + L E+++ D +T+ + L Sbjct: 4051 EDAGTYMCVAQNPAGTALGKIKLNVQVPPV-ISPHLKEYVIA---VDKPITLSCEADGLP 4106 Query: 1226 --DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLK 1280 D+TW+K ++++E + L S +L I D YTC+ + S+T K Sbjct: 4107 PPDITWHKDGRAIVESIRQRVLSSG----SLQIAFVQPGDAGHYTCMAANVAGSSSTSTK 4162 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC--KHTKPSI 1338 + V PP+I E Y + S L P P W ++ ++ K+T Sbjct: 4163 L-TVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTA--- 4218 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 L ++ V D+G Y N G +++T+ P+ P Sbjct: 4219 -EPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPG---------- 4267 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 D N G + + W NI N + + + Sbjct: 4268 ---DVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSG 4324 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEK-PLKNITTEP-NEDIELTCIFGGVPQPKVTWY 1516 + A + + K I ++ P V K + EP + L C G P P + W Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWN 4384 Query: 1517 RDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 R G ++ + + Y C+A N+ G VE S + +Q P+IT+ Sbjct: 4385 RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL 4444 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 E ++ G + ++ G P P + W + G+ + D N+ + + I + Sbjct: 4445 --EPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS---LYIADA 4499 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ +S++ A N G+ V V + V Sbjct: 4500 QKEDTSEFECVARNLMGSVLVRVPVIV 4526 Score = 149 bits (362), Expect = 6e-34 Identities = 233/1097 (21%), Positives = 389/1097 (35%), Gaps = 84/1097 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + PK Q GS++ + C P+P IAW IV + SD Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT--SD----- 663 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I N G Y +A N G L+ E P+++ ++V G+ Sbjct: 664 GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRY----IEAPKLMVVQSELLVALGDIT 719 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ + G P P + W K + ++ + ++ + D G YT A N G Sbjct: 720 VMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG 779 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NN 870 A + V PP+FI +++++ + L V P P+I W R N Sbjct: 780 RATGKITLDV-------GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNM 832 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I S +++ L I N+ + D G Y C A N GK VT+ Sbjct: 833 PIFSRPFSVSSISQLRTGALFILNLWAS-DKGTYICEAENQFGKIQSETTVTVTGLVAPL 891 Query: 931 VKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + EG+ + L C + +W N + + + +G Sbjct: 892 IGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQ 951 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046 + + V T VV +P Q E L + + + Sbjct: 952 LQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPS 1011 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103 V+W + GE+I K+ G LY+ + + GEY C + + A+ V V Sbjct: 1012 VIWSKKGELISTSSAKFSAGADG---SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068 Query: 1104 ELPPEII---TRLQNQK-----VNKGNKATFEIEL-TKGDALVRWFKDGSEIQ-FSNHIQ 1153 + P + L K V G + T E+ + ++ W K+ I FS Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHT 1128 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 G +KI + D+G Y C GN L V P R P+ + V Sbjct: 1129 FLPSG---SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPP--KIQRGPKHLKVQ 1183 Query: 1210 ANTDAYLTVEIPDETLDV-TWYKKKS-VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 + L V TW K S ++ D E D TL I + T D YT Sbjct: 1184 VGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYT 1240 Query: 1268 CVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIK-----RGSDVTLLVDYQAFPQPNDEW 1321 CV + T + ++ + V+ PP + D E Y + + P+P +W Sbjct: 1241 CVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKW 1300 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + N + + + SI L I V D G Y N G + + N+ + P Sbjct: 1301 LHNGRELTG-REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359 Query: 1382 SPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 K + + + + + E E T + I++Y + TE +++ + + Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWY---KDNVQVTESSTIQTVNNGK-- 1414 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNED 1498 I L + Y+ ++I+ S+ +Y+ + + + + N ++ N D Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQ--KYFNI--DVLVPPTIIGTNFPNEVSVVLNRD 1470 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFND 1555 + L C G P P + W++DGK L E Y+C N Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G+ + I P I N + + G+P P + WYK+G + + Sbjct: 1531 AGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMS 1590 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG---- 1671 + +K + I + S S+ YT +N AGT+ + VY P EG Sbjct: 1591 SSQ--ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVY-VPPMIEGNLAT 1647 Query: 1672 PVIMREISRESVTIEWK 1688 P+ + + S+T+E K Sbjct: 1648 PLNKQVVIAHSLTLECK 1664 Score = 147 bits (356), Expect = 3e-33 Identities = 238/1118 (21%), Positives = 422/1118 (37%), Gaps = 93/1118 (8%) Query: 599 IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 I + LSD G E D+ E PP + P V G +L C + Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE--PPPVIQVPNNVTVTPGERAVLTCLI 543 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 ++ + ++ W ++ E + +++ L++ +VK G Y + + G Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-----LELKSVKFNDAGEYHCMVSSEGG 598 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 ++ + L + +EPP+V K+ G V + G P+P I W N+ + Sbjct: 599 SSAASVFLTV----QEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG 654 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI-AETSAVITVEEPTEENAEPPLFI 836 + + +K KD G+Y A NS G + S + +E P + L + Sbjct: 655 -SHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLV 713 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896 +ITV E + + P P + W++ + + PS + + + L+ Sbjct: 714 -ALGDITVME-------CKTSGIPPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQET 762 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSH 954 ++D+GDY CVA N AG+++ ++T+DV E G V L C Q Sbjct: 763 QDLDAGDYTCVAINEAGRAT--GKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYP 820 Query: 955 TVSTKW--YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETST 1008 + KW N S I + R D G C ++Q ++ T Sbjct: 821 EPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSET 880 Query: 1009 MLVVKETIPEFIRKLQDF-EVKEKDVAILEVEI--NSETADVVWERDGEIIKPKKNKYDF 1065 + V + I V E L + + + W ++ ++ +N Y Sbjct: 881 TVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAML--LQNPYIT 938 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGN 1122 + L+I + D GEY+C+ + + T T VV + P I Q +G Sbjct: 939 VRSD--GSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGI 996 Query: 1123 KATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 T + + V W K G I S+ DG L + +++GEY C Sbjct: 997 PVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADG---SLYVVSPGGEESGEYVCTA 1053 Query: 1179 --EVGNSKCTAILTV-EEPSI-----NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTW 1229 G +K LTV P + + P I V A + L E+ +TW Sbjct: 1054 TNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITW 1113 Query: 1230 YKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287 K+ +I + + T + ++ I + D Y CV + V++ V P Sbjct: 1114 AKETQLISPFSPRHTFL---PSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP 1170 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLT 1346 PKI + +++ G V + + Q P P W S ++ +H + + +L+ Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEH---HVSNPDGTLS 1227 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-----PPGKPNILEIDSSSINICW 1401 I + +DAGIY N G + E+ + + + P+ PP E ++ I + Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQ-RIEF 1286 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 P I ++ +E+ E IS+ T I ++ + + AVNE Sbjct: 1287 PCPAKGTPKPTIKWLHNGRELTGREPGISILE-DGTLLVIASVTPYDNGEYICVAVNE-- 1343 Query: 1461 ISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 A T Y + K+ P V ++ + N++ N+ L C G P P + WY+ Sbjct: 1344 ---AGTTERKYNL----KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396 Query: 1518 DGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 D ++ + T N Y C A N G + + + P I Sbjct: 1397 DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIG 1456 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 +N + + + + ++G P P++ W+K+G L + N+ ++ V+ +K Sbjct: 1457 TNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG-DPNVELLDRGQVLHLKNA 1515 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 +R+ +Y SN AG + ++ L +Y PS G V Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNV 1553 Score = 121 bits (291), Expect = 3e-25 Identities = 205/965 (21%), Positives = 343/965 (35%), Gaps = 83/965 (8%) Query: 632 IPPTFS--KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PP + +P+ V + LEC+ A+P P I WL GE + + + Sbjct: 3618 VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGG--- 3674 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L+I N YT VA N G+ + +L + PP + +S+++ Sbjct: 3675 ---RYLQINNADLGDTANYTCVASNIAGKTTREFILTVNV----PPNIKGGPQSLVILLN 3727 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 +S +L G P P ITW K+ + + + ++ V D G Y A N Sbjct: 3728 KSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATN 3787 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 + G + V P P +TV L T P PSI W +N Sbjct: 3788 AAGTDRRRIDLQVHVPPSIAPGPT-------NMTVIVNVQTTLACEATGIPKPSINWRKN 3840 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 +++ + + LVI + + D+ Y+C +N AG +T+ V Sbjct: 3841 GHLLNVDQNQNSYRLLSSGSLVIISPSVD-DTATYECTVTNGAGDDKRTVDLTVQVPPS- 3898 Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 + + + ++ C S + K I + + + Sbjct: 3899 -IADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILAT 3957 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETI--PEFIR-KLQDFEVKEKDVAILEVEINSETAD 1046 G C+ ++ S V + P I+ + + V + +L E + Sbjct: 3958 QLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSP 4017 Query: 1047 -VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--- 1102 + W+++G + + G ++ I D G Y C+ ++ + TA + Sbjct: 4018 FITWQKEGINVNTSGRNHAVLPSGGLQ---ISRAVREDAGTYMCVAQNPAGTALGKIKLN 4074 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDGSEIQFSNHIQLTIDG 1158 V++PP I L+ + T E D L + W KDG I S ++ G Sbjct: 4075 VQVPPVISPHLKEYVIAVDKPITLSCE---ADGLPPPDITWHKDGRAIVESIRQRVLSSG 4131 Query: 1159 KKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPE-FILVPANTD 1213 L+I DAG Y+C G+S + LTV P +R E V N+ Sbjct: 4132 S---LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP---RIRSTEGHYTVNENSQ 4185 Query: 1214 AYLT-VEIPDETLDVTWYKKKSVIEDT-EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 A L V T + W K ++ + K+T LI+ +D YTCV Sbjct: 4186 AILPCVADGIPTPAINWKKDNVLLANLLGKYTA---EPYGELILENVVLEDSGFYTCVAN 4242 Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 +A V + V P + + + +G + L P P W N+ II Sbjct: 4243 NAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPA 4302 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 H S++ S L I++V D+G Y EN+ G V + + P + Sbjct: 4303 --HFD-SVNGHS-ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP-------VF 4351 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 + D S W EP G + I+ V+ T +W + I+ L S Sbjct: 4352 KGDYPS---NWIEP--LGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGS--- 4403 Query: 1451 FRAYAVNEVDISD-ASETTEYYKVIKET---KIQSPTV--EKPLKNITTEPNEDIELTCI 1504 Y D D T V++ + +QSP + +P++ + + I L C Sbjct: 4404 LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGK-IILNCQ 4462 Query: 1505 FGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 G PQP +TW R G + + + ++C+A N G V Sbjct: 4463 ATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRV 4522 Query: 1564 VVGIQ 1568 V +Q Sbjct: 4523 PVIVQ 4527 Score = 55.2 bits (127), Expect = 2e-05 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 5/81 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V C GYP+P+I W I S ++M D TL I+ P+DAG + C Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD----GTLFIKNAAPKDAGIYGC 681 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 +A N+AG + L +EAP Sbjct: 682 LASNSAGTDKQNSTLRYIEAP 702 Score = 51.6 bits (118), Expect = 2e-04 Identities = 42/146 (28%), Positives = 58/146 (39%), Gaps = 5/146 (3%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 E L + +G++V EC+ P P ITW++ +I S ++ D L I++ Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ---MLHIKKA 3120 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP 633 D G + C A N AG L V P S G E V D GIP Sbjct: 3121 EVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCD-ATGIP 3179 Query: 634 PTFSKKPKAQYVDEGSDILLECRLVA 659 P K E SD LE R+++ Sbjct: 3180 PPTIAWLKNHKRIENSD-SLEVRILS 3204 Score = 51.2 bits (117), Expect = 3e-04 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G EC+ G P PQ+ WF+ ++PS D + L I+E DAG +TC Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPS---TFLIIDPLLGLLKIQETQDLDAGDYTC 772 Query: 584 VAKNAAGFASSTTELIVEAP 603 VA N AG A+ L V +P Sbjct: 773 VAINEAGRATGKITLDVGSP 792 Score = 49.2 bits (112), Expect = 0.001 Identities = 35/117 (29%), Positives = 50/117 (42%), Gaps = 10/117 (8%) Query: 489 NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 ++K ++ V PT + ++ V K +P V +C G P P ITW + Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKP--------VALQCIANGIPNPSITWLKDDQ 1865 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + +Q V L I + EDAG +TCVA NAAG +L V P S Sbjct: 1866 PVNTAQGNLKIQSSGRV--LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920 Score = 48.8 bits (111), Expect = 0.002 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 7/95 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568 P F E G ++ C+ G P P++TW II P+ ++D N + L Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII-PA-----HFDSVNGHSEL 4313 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 VI V ED+GT+ C A+N+ GF + + V+ P Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348 Score = 47.2 bits (107), Expect = 0.005 Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 14/203 (6%) Query: 469 VPAQYLMDENNYTQYLQKKLN--EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGST 526 +P + D YT ++ EK + V+ P E P+ K + Sbjct: 1605 IPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPL------NKQVVIAHS 1658 Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 + EC+ G P P +TW + +K + + ++ + + +E+ D G + CVA Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVAT 1715 Query: 587 NAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 + AG E+ ++ P + G E + + PPT Q + Sbjct: 1716 SVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI 1775 Query: 646 DE--GSDILLECRLVAIPEPDIA 666 DE G ILL R + I + ++ Sbjct: 1776 DERDGFKILLNGRKLVIAQAQVS 1798 Score = 47.2 bits (107), Expect = 0.005 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P G C+V+G P P I W R+ I+ S + + +L I EDAG + Sbjct: 4362 PLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGN----GSLAIYGTVNEDAGDY 4417 Query: 582 TCVAKNAAGFASSTTELIVEAP 603 TCVA N AG + L +++P Sbjct: 4418 TCVATNEAGVVERSMSLTLQSP 4439 Score = 45.6 bits (103), Expect = 0.015 Identities = 38/185 (20%), Positives = 69/185 (37%), Gaps = 4/185 (2%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541 PT + +++ E + L+C G+P PK+TW + + + Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVS 4319 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C A N G V+ V +++ PV + +G ++ ++G P Sbjct: 4320 KEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFK-GDYPSNWIEPLGGNAILNCEVKGDPT 4378 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P + W + G +E + I S + I + YT A+N AG ++L Sbjct: 4379 PTIQWNRKGVDIE--ISHRIRQLGNGS-LAIYGTVNEDAGDYTCVATNEAGVVERSMSLT 4435 Query: 1662 VYDKP 1666 + P Sbjct: 4436 LQSPP 4440 Score = 45.2 bits (102), Expect = 0.020 Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 + S C +G P P I W + ++ + Y + L++ V ED+G +T Sbjct: 4182 ENSQAILPCVADGIPTPAINWKKDNVLLA---NLLGKYTAEPYGELILENVVLEDSGFYT 4238 Query: 583 CVAKNAAGFASSTTELIV 600 CVA NAAG + T L V Sbjct: 4239 CVANNAAGEDTHTVSLTV 4256 Score = 44.0 bits (99), Expect = 0.046 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 5/106 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ + H + + C+ G P P ITW ++ + S L Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQ 4044 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP--LSDHGSEMTV 613 I EDAGT+ CVA+N AG A +L V+ P +S H E + Sbjct: 4045 ISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVI 4090 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + CQ G P+P ITW RQ I S D ++ +N +L I + ED F C Sbjct: 4454 GGKIILNCQATGEPQPTITWSRQGHSI--SWDDRVNVLSNN--SLYIADAQKEDTSEFEC 4509 Query: 584 VAKNAAGFASSTTELIVE 601 VA+N G +IV+ Sbjct: 4510 VARNLMGSVLVRVPVIVQ 4527 Score = 37.1 bits (82), Expect = 5.3 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 KH P T C G P P I W + + P D + L + A Sbjct: 3910 KHAPAVIT----CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQL---NHA 3962 Query: 579 GTFTCVAKNAAGFASSTTELIVEAP 603 G +TCVA+NAAG A L V P Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEP 3987 >UniRef50_Q4T3W5 Cluster: Chromosome undetermined SCAF9901, whole genome shotgun sequence; n=6; Fungi/Metazoa group|Rep: Chromosome undetermined SCAF9901, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 4648 Score = 231 bits (564), Expect = 2e-58 Identities = 172/616 (27%), Positives = 282/616 (45%), Gaps = 41/616 (6%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436 DKPS PG+ +I+++ ++S+ I W PE G ++ Y VE ++ + W + + + + Sbjct: 2147 DKPSQPGEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCNKQRLKEK 2206 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 ++ L + Y FR A NE IS T K + Q P++ K + +TT+ Sbjct: 2207 DFTVAGLAEATEYEFRVLAENETGISRPRRTATCIKTKLSVECQ-PSLRKEMDEVTTKLG 2265 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 + + C G P P + WY GK++ K ++ Y C A Sbjct: 2266 QPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHSLSIITDQQEDEGEYTCKA 2325 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNG 1610 ND GE ETS ++ ++ P + +K + +G + V G P P+++W Sbjct: 2326 INDAGEAETSGILMLEAAPSFH-PDYPLKDTYCTGLGTTLRIHVVYIGRPQPKIMWLHGA 2384 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRS-HSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 LEN ++ I T E + + IK ++R H KY I N G + +++YDKP +P Sbjct: 2385 KTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHNHFGRADTAFNVEIYDKPDRP 2444 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE-PDNNRWIKVADVDRDVETYC- 1727 GP+I+ + + SV I WKPP DDGG +T Y +EKHE + W V+ T C Sbjct: 2445 RGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEWELVSSSING--TSCR 2502 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L ++ Y FRV AQN G SE LE + PI+IK+ L+ PS I +S + Sbjct: 2503 VPNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPS-PPLCPIVSGITKDSCVV 2561 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR-----IQKLSINTTYQFRIY 1840 +W P +GGS I Y +E+K + K+ W + ++ L+ Y FR+ Sbjct: 2562 SWKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVFRVK 2621 Query: 1841 ARNEIGTSLPYTSDDKITIGKT----LTPPS---QPRNFVVSESTSRSVTLKWT-EPESN 1892 N +G Y S++ ++I + P+ + RN V ++ ++ K T +P+ Sbjct: 2622 CEN-LGGQSDY-SEETLSIHPAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPK-- 2677 Query: 1893 GGSPITNYIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 P+ ++ K + GK KI G H+ I + E+D +++I A N G Sbjct: 2678 ---PVVKWLRRGKEIHSDGKK-IKIQEFKGGYHQLVISEVDEEDSTVYQIRATNQGGSIC 2733 Query: 1951 PTESQSVRLEKHATVP 1966 T S V + +P Sbjct: 2734 ATISLDVEVPAKIHLP 2749 Score = 218 bits (533), Expect = 1e-54 Identities = 172/692 (24%), Positives = 290/692 (41%), Gaps = 28/692 (4%) Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 VE +E P + D ++ ++ G + L V P P W + + + + Sbjct: 1157 VERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITWSKSETDLHNRGFIE--V 1214 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 + S +L I KV DAG Y + EN+ G + + V + D P P I E+ S+ Sbjct: 1215 TNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKVYDTPGPTRPIKIKELTKESVT 1274 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVN 1457 I W+ P G + + Y++E +E + +V + +KT I L Y FR N Sbjct: 1275 ISWEAPAIDGGAPVNNYIIERREASMRAYKTVTSKCSKTTFKIDGLMEGMLYYFRVLPEN 1334 Query: 1458 EVDISDASETTEYYKV----IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 I + ET + V + K++ V K + E E + + G + + Sbjct: 1335 IYGIGEPRETPDAILVCEVPLSPHKLEVIDVTKTTVTLGWEKPEHDGGSRLTGYIIEACK 1394 Query: 1514 TWYRDGKKLKTAKAT-YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---CVVGIQQ 1569 K+ T K T +E+ ++ A N G E V +Q+ Sbjct: 1395 FGTDRWMKVATLKTTDFEH----TIEKLNESEQYLFRIRAINSRGASEPKELVTAVTVQE 1450 Query: 1570 KPVIT-ISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 + V+ + I QK G + I G PPP WY N+++ + + Sbjct: 1451 QRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYFRENRIKITDRIHFKSTG 1510 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 K S + I + + YT+E +N G S + + + KP +P+GP+ EI +VT Sbjct: 1511 KFSKLVIHDTNIDDTGDYTLEVTNAVGLISEVIKVIILSKPDEPKGPLRFDEIDATTVTC 1570 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQ 1744 W PP+ DGG ++ + +E+ + W+ V + V R T+ + L E EY+FR A Sbjct: 1571 SWDPPIRDGGAPISGFVVEQRDAHRPGWVTVCESVSR--PTFKFENLIEGDEYVFRAAAT 1628 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N G E L+SE + K+ +VP I + + + W P E++GG + Y + Sbjct: 1629 NRYGTGEFLQSEIVTCKSLTNVPG-PPGRPTVFDISRDGMTVAWNPPEEDGGLEVSGYII 1687 Query: 1805 EIKQ-EGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 E K+ +W R + + Y+ R+ A N G S P Sbjct: 1688 ERKEVRSDRWVRANKNPITMTRYRSTELIEGLEYEHRVTALNAKGLSKPSLPSKPAVATD 1747 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 + PP P+N ++++T SV+L W+ P+ G + + Y+IE + V +W K T Sbjct: 1748 PIDPPGCPQNPRITDTTKTSVSLAWSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSL 1807 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 + E+ + N+ + +E FR+ A N G P E Sbjct: 1808 ICEYTLTNMPQGEEFKFRVMACNAGGSGEPAE 1839 Score = 198 bits (484), Expect = 1e-48 Identities = 134/448 (29%), Positives = 200/448 (44%), Gaps = 20/448 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P P W K+ L + I + E S + IK +RS S Y + N G Sbjct: 1879 IRGKPQPTCKWSKDFGALSTNAM--IVSTEDVSELVIKGAERSDSGLYDLLLENRVGKKK 1936 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 ++ +KV +PS PEGP++ +I SV + WK P+D+GG E+ Y +E+ E N W Sbjct: 1937 AQIKVKVIGRPSAPEGPLVFDDIHANSVKVSWKVPIDNGGSEILGYILERREATRNAWYT 1996 Query: 1716 VADVDRDVETYCIQK-LNENCEYMFRVIAQNPVGFSEALESE-PIVIKTALDVPSXXXXX 1773 V R ET + K L E EY F+V A+N GFS +L+SE P+V KT L P Sbjct: 1997 VE--SRITETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHPVVPKTPLCSPEPPSTP 2054 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW-KXXXXXXXXXARIQKLSI 1831 I SV + W + +GGS + Y VE + W + + L+ Sbjct: 2055 PEIMDITKNSVALAWSRPKDDGGSAVTGYFVEYRIVSSDTWSRHETQITSTMFTLSGLTP 2114 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 ++ YQFRI+A N IG S D +T PSQP + + T+ SV ++W PE Sbjct: 2115 DSEYQFRIFAVNSIGESEAGPVSDSVTCKDPFDKPSQPGEIDIVQVTNNSVAIRWQAPEC 2174 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 +GG + Y +E + +W K + + + E E FR+ AEN G+S P Sbjct: 2175 DGGKEVLGYWVECRKSIESTWKKCNKQRLKEKDFTVAGLAEATEYEFRVLAENETGISRP 2234 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + + ++ +V P+ E+ + V T G P ++ I R V Sbjct: 2235 RRTATC-IKTKLSVECQPSLRKEM-----DEVTTKLGQP------AIMKCQIIGRPVPDI 2282 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 W GK V + K+ + NH+ I Sbjct: 2283 KWYHAGKEIVESRKYQMSSDGRNHSLSI 2310 Score = 188 bits (459), Expect = 1e-45 Identities = 215/958 (22%), Positives = 398/958 (41%), Gaps = 69/958 (7%) Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 K ++ +++ GE+S ++ + +E P + L + I + A L+V+ Sbjct: 1131 KYYFRVAGVNINGTGEFSEPCAAAE--PVERIETPDVELADDLKKTICLRAGGSLRLSVK 1188 Query: 1220 IPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276 + + +TW K ++ + + F +++ TLII K D +YT V ++ K Sbjct: 1189 VTGRPVPAITWSKSETDLHN-RGFIEVTNTST-TLIIDKVHRYDAGKYTVVAENSAGKQE 1246 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK- 1335 + V+V + P R +IK + ++ + ++A P + VN+ II++ + + Sbjct: 1247 ANILVKVYDTPGPT----RPIKIKELTKESVTISWEA-PAIDGGAPVNNYIIERREASMR 1301 Query: 1336 --PSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMN---VTILDKPSPPGKPN 1388 ++ SK + T K + +Y R+ EN G + + + + P P K Sbjct: 1302 AYKTVTSKCSKTTFKIDGLMEGMLYYFRVLPENIYGIGEPRETPDAILVCEVPLSPHKLE 1361 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTN 1446 ++++ +++ + W++PE+ G S + Y++E + T W+ V + T + +I+ L + Sbjct: 1362 VIDVTKTTVTLGWEKPEHDGGSRLTGYIIEACKFGTDRWMKVATLKTTDFEHTIEKLNES 1421 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIELTC 1503 Y FR A+N S+ E ++E ++ P V+ P K I + +EL Sbjct: 1422 EQYLFRIRAINSRGASEPKELVTAV-TVQEQRVM-PEVDFSAIPQKVINVLAGKTLELDL 1479 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE--VET 1561 G P P +WY ++K + +D G+ +E Sbjct: 1480 PIVGRPPPVCSWYFRENRIKITDRIHFKSTGKFSKLVIHDTN-------IDDTGDYTLEV 1532 Query: 1562 SCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPP--EVIWYKNGNKLENDK 1617 + VG+ + VI +S D + DE T V PP + +G +E Sbjct: 1533 TNAVGLISEVIKVIILSKPDEPKGPLRFDEIDATTVTCSWDPPIRDGGAPISGFVVEQRD 1592 Query: 1618 EYN---ITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGT----SSVEVTLKVYDKPSK 1668 + +T E S + + L + A+N GT S VT K Sbjct: 1593 AHRPGWVTVCESVSRPTFKFENLIEGDEYVFRAAATNRYGTGEFLQSEIVTCKSLTNVPG 1652 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P G + +ISR+ +T+ W PP +DGGLE++ Y IE+ E ++RW++ + Y Sbjct: 1653 PPGRPTVFDISRDGMTVAWNPPEEDGGLEVSGYIIERKEVRSDRWVRANKNPITMTRYRS 1712 Query: 1729 QKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 +L E EY RV A N G S+ +L S+P V +D P SV + Sbjct: 1713 TELIEGLEYEHRVTALNAKGLSKPSLPSKPAVATDPIDPPGCPQNPRITDT-TKTSVSLA 1771 Query: 1788 WFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNE 1844 W P + G + + Y +E+++ G W + + ++FR+ A N Sbjct: 1772 WSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSLICEYTLTNMPQGEEFKFRVMACNA 1831 Query: 1845 IGTSLPYTSDDKITIGKTLTPPS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 G+ P +T+ + L P +P+ + + + ++ + P P + Sbjct: 1832 GGSGEPAEVPGTVTVTEMLESPDFDLEPK-YKDLYTVRQGGVVRLSVPIRGKPQPTCKWS 1890 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +F + S ++ V E I+ + D ++ + EN VG + +++ K Sbjct: 1891 KDFGAL---STNAMIVSTEDVSELVIKGAERSDSGLYDLLLENRVG----KKKAQIKV-K 1942 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 PS P PL + +N V SW P +GG+ +LGY + R+ T+ W V + + Sbjct: 1943 VIGRPSAPEGPLVFDDIHANSVKVSWKVPIDNGGSEILGYILERREATRNAWYTV-ESRI 2001 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 + ++ L E Y ++ A N G S L+S+ P V+P + E P E+ Sbjct: 2002 TETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHP--VVPKTPLCSPEPPSTPPEI 2057 Score = 182 bits (444), Expect = 7e-44 Identities = 150/658 (22%), Positives = 296/658 (44%), Gaps = 43/658 (6%) Query: 1191 VEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKFTLI 1245 V+EP I T L E L+ + + + T+++P +TW ++ +++T++ ++ Sbjct: 433 VKEPHIEPTADLSEIDGQLIMSRSGSTFTIDVPISGRPAPKITWKLEEMRLKNTDRVSIK 492 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305 + ++ +++ D +Y +L +A T V+V K I + Sbjct: 493 EAQNRTSISVKEAMRGDSGKYNLILENAAGTKTFVVDV-NVIGKPSPPTGPIEISSITAE 551 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS---IDS--KSASLTIKKVENTDAGIYKL 1360 + ++++ P+ + + + I++K + + I+S K SL + + +++ Sbjct: 552 SCILNWHP-PEDDGGTDITNYIVEKRESGSTAWQLINSSVKRTSLFVSHLTKYMQYTFRV 610 Query: 1361 RLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 ENN G + + TI+ + P PP +P++ I ++++ + W+EP + G S + Y Sbjct: 611 SAENNFGVSKATESETIVAEHPFTPPGPPTRPSVFNITANTMTLKWEEPYHDGGSKVTGY 670 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +E +E + W+ I + + ++L Y+FR YA+N +S ASE ++ Sbjct: 671 WIEKKERNNILWVRENKIPCFECNYRAESLVEGLEYQFRVYAMNSAGLSKASEASK--GA 728 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKA 1527 + + + PT KP T ++ + P V + + K + K Sbjct: 729 VAQNPVDPPT--KPEVTNVTRTTVSLKWSAPLNDGGSPIVGYIIERKPYTLTGEGRWLKC 786 Query: 1528 TYENRXXXXXXXXXXXXXXXY--KCIAFNDHG--EVETSCVVGIQQK-----PVITISNE 1578 Y N Y + IA N + + + +Q K P + ++ Sbjct: 787 NYTNVTDTFYTVTALGEGEPYEFRVIAKNANQVCSIPSESTGSVQCKTDFEPPKAQLDSK 846 Query: 1579 DIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 + + V G + ++ A + G P P+ W K +L+ ++Y++ ++ IK Sbjct: 847 LMSETVMVRAGSDLVLDAAVGGRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCD 906 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 R + KY + N +GT + EV++KV D P EG + + +++ ES T+ WKPP++DGG Sbjct: 907 RDDTGKYILTVKNVSGTKTAEVSVKVLDTPGVCEGSITISKVTEESCTLSWKPPVEDGGD 966 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +++ Y +E+ + + W+ V +++ I +L +N EY+FRV N G L+SE Sbjct: 967 DVSHYIVERRDTNRLNWVIVHAECKELNCN-ITRLFKNTEYLFRVRGVNKYGPGVYLQSE 1025 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW 1813 P+V + VPS + I W E +GGSP+I Y VE ++ + +W Sbjct: 1026 PMVARNTFTVPSPPGSPEIVAS-GKDFATIEWMKPESDGGSPLIHYLVERREKKSARW 1082 Score = 181 bits (441), Expect = 2e-43 Identities = 121/406 (29%), Positives = 191/406 (47%), Gaps = 16/406 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + + I G P P++ W +L+N +I + + I +KE R S KY + Sbjct: 457 GSTFTIDVPISGRPAPKITWKLEEMRLKNTDRVSIKEAQNRTSISVKEAMRGDSGKYNLI 516 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 N AGT + V + V KPS P GP+ + I+ ES + W PP DDGG ++T Y +EK Sbjct: 517 LENAAGTKTFVVDVNVIGKPSPPTGPIEISSITAESCILNWHPPEDDGGTDITNYIVEKR 576 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 E + W + + + + L + +Y FRV A+N G S+A ESE IV + Sbjct: 577 ESGSTAWQLINSSVKRTSLF-VSHLTKYMQYTFRVSAENNFGVSKATESETIVAEHPF-T 634 Query: 1767 PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXX 1823 P I ++ + W +GGS + Y +E K+ W + Sbjct: 635 PPGPPTRPSVFNITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVRENKIPCFECN 694 Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883 R + L YQFR+YA N G S + + PP++P V+ T +V+ Sbjct: 695 YRAESLVEGLEYQFRVYAMNSAGLSKASEASKGAVAQNPVDPPTKPE---VTNVTRTTVS 751 Query: 1884 LKWTEPESNGGSPITNYIIEFK--TVKGKS-WTKIVTVGGSVHEHCIENIKEKDEIIFRI 1940 LKW+ P ++GGSPI YIIE K T+ G+ W K + + + + E + FR+ Sbjct: 752 LKWSAPLNDGGSPIVGYIIERKPYTLTGEGRWLKCNYTNVTDTFYTVTALGEGEPYEFRV 811 Query: 1941 SAENTVGV-SLPTESQ-SVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 A+N V S+P+ES SV+ + T PP A L+ +++ +++ Sbjct: 812 IAKNANQVCSIPSESTGSVQCK---TDFEPPKAQLDSKLMSETVMV 854 Score = 174 bits (423), Expect = 3e-41 Identities = 180/712 (25%), Positives = 301/712 (42%), Gaps = 53/712 (7%) Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 R +C VE P + + G A + ++ ++W+ G EI S Sbjct: 2236 RTATCIKTKLSVECQPSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESR 2295 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLPEF 1205 Q++ DG+ L I +D GEY+C + G ++ + IL +E PS + L + Sbjct: 2296 KYQMSSDGRNHSLSIITDQQEDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDYPLKDT 2355 Query: 1206 ILVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 T + V I + W +E+TE T+ + LII+ Sbjct: 2356 YCTGLGTTLRIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHG 2415 Query: 1265 -EYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 +Y L + ++ T VE+ + P + + + S +++ ++ P + Sbjct: 2416 GKYRIRLHNHFGRADTAFNVEIYDKPDRPRGPIILDALLKNS---VIISWKP-PTDDGGC 2471 Query: 1322 IVNSKIIKKCKHTKPS---IDSKSASLTIKKVEN-TDAGIYKLRL--ENNCGHAD-VEMN 1374 ++ + I++K + + + S S + T +V N TD+ Y R+ +N G+++ +E+ Sbjct: 2472 MITNYIVEKHEDKEGGEWELVSSSINGTSCRVPNLTDSAGYFFRVYAQNRYGNSEPLELT 2531 Query: 1375 VTIL-----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-- 1427 IL +KPSPP P + I S + W P + G S I Y +E + D EW Sbjct: 2532 SPILIKSQLEKPSPPLCPIVSGITKDSCVVSWKPPISDGGSKIKSYCLEMKYKDKREWSE 2591 Query: 1428 ---ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 ++ I +T S++ L Y FR N SD SE T +I++P Sbjct: 2592 WTPVTTDEIKQTVFSVKCLTEGVEYVFRVKCENLGGQSDYSEETLSIHPAAAIEIRAPAF 2651 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGKKLKTA--KATYENRXXX 1535 ++ L+N++ + + L C G P+P V W R DGKK+K K Y Sbjct: 2652 KEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQEFKGGYHQ---L 2708 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWL 1591 Y+ A N G + + + ++ I + +++K K + G+ Sbjct: 2709 VISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIHLP-KNLKDKEAIPALRGEVVN 2767 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + G P P + W K + ++++ Y I T+ TS++ +++ + Y + A N Sbjct: 2768 IKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYIVCAKNR 2827 Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 G V L V D P P G V +ISR+SVT+ W P +DGG + Y IEK Sbjct: 2828 FGIDQQTVELDVADVPDPPRG-VKASDISRDSVTLNWVAPANDGGSRVISYIIEKCPTTA 2886 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761 RW +VA RD Y + L Y FRVIA+N G S E S P++ K Sbjct: 2887 ERWQRVAQ-SRDTH-YTVINLFGGTSYQFRVIAENKFGQSAPSETSGPVMTK 2936 Score = 170 bits (414), Expect = 3e-40 Identities = 206/918 (22%), Positives = 353/918 (38%), Gaps = 84/918 (9%) Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 + E ++V A +D L + W K ++ EK+ L + +I+ C Sbjct: 848 MSETVMVRAGSDLVLDAAVGGRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCDR 907 Query: 1261 DDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 DD +Y + + T ++ V+V++ P E I + ++ + + ++ + Sbjct: 908 DDTGKYILTVKNVSGTKTAEVSVKVLDTPGVC---EGSITISKVTEESCTLSWKPPVEDG 964 Query: 1319 DE----WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 + +IV + + + K + I ++ ++++R N G + Sbjct: 965 GDDVSHYIVERRDTNRLNWVIVHAECKELNCNITRLFKNTEYLFRVRGVNKYGPGVYLQS 1024 Query: 1375 VTILDK-----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE----------- 1418 ++ + PSPPG P I+ I W +PE+ G S +I+Y+VE Sbjct: 1025 EPMVARNTFTVPSPPGSPEIVASGKDFATIEWMKPESDGGSPLIHYLVERREKKSARWVK 1084 Query: 1419 ---------------YQEIDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 QE T EW K + T+ + L + Y FR VN Sbjct: 1085 INRDGGAEVIGYILEMQEAGTEEWKKAHEKTLRGTEYVVIGLSAATKYYFRVAGVNINGT 1144 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKP---LKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + SE + ++ +I++P VE K I + L+ G P P +TW + Sbjct: 1145 GEFSEPCAAAEPVE--RIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITWSKS 1202 Query: 1519 GKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 L Y +A N G+ E + +V + P T Sbjct: 1203 ETDLHNRGFIEVTNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKVYDTPGPTRP 1262 Query: 1577 NEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 + IK+ K V W A+ G P I + + K +T+K + +I Sbjct: 1263 IK-IKELTKESVTISWEAPAIDGGAPVNNYIIERREASMRAYK--TVTSKCSKTTFKIDG 1319 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 L + + N G T + V + P P ++ ++++ +VT+ W+ P Sbjct: 1320 LMEGMLYYFRVLPENIYGIGEPRETPDAILVCEVPLSPHKLEVI-DVTKTTVTLGWEKPE 1378 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 DGG LT Y IE + +RW+KVA + + I+KLNE+ +Y+FR+ A N G Sbjct: 1379 HDGGSRLTGYIIEACKFGTDRWMKVATLKTTDFEHTIEKLNESEQYLFRIRAINSRG--- 1435 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI----K 1807 SEP + TA+ V + V PI+ + Sbjct: 1436 --ASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYF 1493 Query: 1808 QEGKKWKXXXXXXXXXARIQKL-----SINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 +E + + KL +I+ T + + N +G + K+ I Sbjct: 1494 RENRIKITDRIHFKSTGKFSKLVIHDTNIDDTGDYTLEVTNAVGL---ISEVIKVIILSK 1550 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P P F E + +VT W P +GG+PI+ +++E + W VTV SV Sbjct: 1551 PDEPKGPLRF--DEIDATTVTCSWDPPIRDGGAPISGFVVEQRDAHRPGW---VTVCESV 1605 Query: 1923 HEHC--IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 EN+ E DE +FR +A N G +S+ V + VP PP P + + Sbjct: 1606 SRPTFKFENLIEGDEYVFRAAATNRYGTGEFLQSEIVTCKSLTNVPGPPGRP-TVFDISR 1664 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + + +W PE DGG + GY I ++V W+ K + ++ +L E Y R Sbjct: 1665 DGMTVAWNPPEEDGGLEVSGYIIERKEVRSDRWVRANKNPITMTRYRSTELIEGLEYEHR 1724 Query: 2041 IYARNEIGLSEPLESDEP 2058 + A N GLS+P +P Sbjct: 1725 VTALNAKGLSKPSLPSKP 1742 Score = 136 bits (330), Expect = 5e-30 Identities = 117/492 (23%), Positives = 201/492 (40%), Gaps = 25/492 (5%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-- 1435 +D P P P I + +S+++ W P++ G++ + Y++E Q++ TT WI Sbjct: 1749 IDPPGCPQNPRITDTTKTSVSLAWSPPDDEGDARVDGYLIEMQKVGTTAWIKCNTTPSLI 1808 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTE 1494 + ++ N+ ++FR A N + +E V + + +E K++ T Sbjct: 1809 CEYTLTNMPQGEEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVR 1868 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIA 1552 + L+ G PQP W +D L T + E+ Y + Sbjct: 1869 QGGVVRLSVPIRGKPQPTCKWSKDFGALSTNAMIVSTEDVSELVIKGAERSDSGLYDLLL 1928 Query: 1553 FNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY-K 1608 N G+ + V+G P + +DI + V W V G E++ Y Sbjct: 1929 ENRVGKKKAQIKVKVIGRPSAPEGPLVFDDI-HANSVKVSWKVPIDNGG---SEILGYIL 1984 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-TSSVEVTLKVYDK-- 1665 + + Y + ++ + + +K LK + + A N+ G +SS++ V K Sbjct: 1985 ERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKVTAENSFGFSSSLKSEHPVVPKTP 2044 Query: 1666 ---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P P P + +I++ SV + W P DDGG +T Y +E ++ W + + Sbjct: 2045 LCSPEPPSTPPEIMDITKNSVALAWSRPKDDGGSAVTGYFVEYRIVSSDTWSR-HETQIT 2103 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 + + L + EY FR+ A N +G SEA S+ + K D PS + N Sbjct: 2104 STMFTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSVTCKDPFDKPS-QPGEIDIVQVTN 2162 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQE-GKKWK--XXXXXXXXXARIQKLSINTTYQFR 1838 SV I W E +GG ++ Y VE ++ WK + L+ T Y+FR Sbjct: 2163 NSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCNKQRLKEKDFTVAGLAEATEYEFR 2222 Query: 1839 IYARNEIGTSLP 1850 + A NE G S P Sbjct: 2223 VLAENETGISRP 2234 Score = 126 bits (305), Expect = 5e-27 Identities = 93/335 (27%), Positives = 145/335 (43%), Gaps = 11/335 (3%) Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 DV I+ + ++ ++ +N VG +A I +K + PS I Sbjct: 1907 DVSELVIKGAERSDSGLYDLLLENRVGKKKA----QIKVKV-IGRPSAPEGPLVFDDIHA 1961 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQK-LSINTTYQFRI 1839 SV ++W NGGS I+ Y +E ++ + W + K L T Y F++ Sbjct: 1962 NSVKVSWKVPIDNGGSEILGYILERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKV 2021 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPIT 1898 A N G S S+ + L P P + + T SV L W+ P+ +GGS +T Sbjct: 2022 TAENSFGFSSSLKSEHPVVPKTPLCSPEPPSTPPEIMDITKNSVALAWSRPKDDGGSAVT 2081 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSV 1957 Y +E++ V +W++ T S + + E FRI A N++G S S SV Sbjct: 2082 GYFVEYRIVSSDTWSRHETQITSTM-FTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSV 2140 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + PS P ++I V +N V W PE DGG +LGY + R ++ W + Sbjct: 2141 TCKDPFDKPSQP-GEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKSIESTWKKCN 2199 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 K + F + L+E Y R+ A NE G+S P Sbjct: 2200 KQRLKEKDFTVAGLAEATEYEFRVLAENETGISRP 2234 Score = 124 bits (299), Expect = 3e-26 Identities = 84/293 (28%), Positives = 128/293 (43%), Gaps = 9/293 (3%) Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXX 1816 +V + PS I ES + W P E +GG+ I +Y VE ++ G W+ Sbjct: 527 VVDVNVIGKPSPPTGPIEISSITAESCILNWHPPEDDGGTDITNYIVEKRESGSTAWQLI 586 Query: 1817 XXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS 1875 + + L+ Y FR+ A N G S T + I TPP P V Sbjct: 587 NSSVKRTSLFVSHLTKYMQYTFRVSAENNFGVSKA-TESETIVAEHPFTPPGPPTRPSVF 645 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 T+ ++TLKW EP +GGS +T Y IE K W + + + E++ E E Sbjct: 646 NITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVRENKIPCFECNYRAESLVEGLE 705 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 FR+ A N+ G+S +E+ + ++ PPT P E+ V V W P DGG Sbjct: 706 YQFRVYAMNSAGLSKASEASKGAVAQNPV--DPPTKP-EVTNVTRTTVSLKWSAPLNDGG 762 Query: 1996 APLLGYNIAIRDVTKT---MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 +P++GY I + T T W++ +V + + L E Y R+ A+N Sbjct: 763 SPIVGYIIERKPYTLTGEGRWLKCNYTNVTDTFYTVTALGEGEPYEFRVIAKN 815 Score = 122 bits (295), Expect = 8e-26 Identities = 69/255 (27%), Positives = 118/255 (46%), Gaps = 5/255 (1%) Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 +G P P ++W K+ L+ ++ E + + IK +++ + KYT+ N S Sbjct: 105 KGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSF 164 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 + + PSKP GP+ + E+ +S+ I W P DDGG ++T Y +EK + + W Sbjct: 165 HIHVITLGPPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTVEKRDTSQSNWKMA 224 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 +D + + + L + +Y F+V A+N G SE L S+ ++ K P Sbjct: 225 CSHVQDTQ-FKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFR-PPGPPGKPVV 282 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXA--RIQKLSINT 1833 + ++ + I W +GG+PI + VE K+ W+ RI L Sbjct: 283 YNVTSDGMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGL 342 Query: 1834 TYQFRIYARNEIGTS 1848 Y FR+YA+N+ G S Sbjct: 343 EYSFRVYAQNDAGFS 357 Score = 117 bits (281), Expect = 4e-24 Identities = 93/377 (24%), Positives = 165/377 (43%), Gaps = 17/377 (4%) Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W P DGG ++ Y IEK D W + R E + ++KL E+ E FRV A+N Sbjct: 1 WLKPSYDGGSIISDYIIEKKLKDEE-W-SLGGTSRQCE-FEVKKLKEHSEVFFRVAARNE 57 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXID---NESVYITWFPSEKNGGSPIIDYK 1803 G E + PI + + P + +V+I P + ++ K Sbjct: 58 KGQGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHNVHIE-LPYKGKPKPSMLWLK 116 Query: 1804 VEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 + +E ++ + I+ + ++ + N++ + IT+G Sbjct: 117 DNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIH--VITLG-- 172 Query: 1863 LTPPSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 PPS+P + + E + S+ + W EP +GG IT Y +E + +W K+ Sbjct: 173 --PPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTVEKRDTSQSNW-KMACSHVQ 229 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 + + N+ + + F++ AEN GVS P SQ V + P PP P+ + V S+ Sbjct: 230 DTQFKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPV-VYNVTSD 288 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 + W P +DGG P+ G+++ +++ MW +V + + ++ I L E Y R+ Sbjct: 289 GMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFRV 348 Query: 2042 YARNEIGLSEPLESDEP 2058 YA+N+ G S + +P Sbjct: 349 YAQNDAGFSRIGDESKP 365 Score = 114 bits (274), Expect = 3e-23 Identities = 67/222 (30%), Positives = 109/222 (49%), Gaps = 7/222 (3%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 ++ + N GT + D + IGK +PP+ P +S T+ S L W PE +GG+ Sbjct: 512 KYNLILENAAGTKT-FVVDVNV-IGKP-SPPTGP--IEISSITAESCILNWHPPEDDGGT 566 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 ITNYI+E + +W +++ + ++ + + FR+SAEN GVS TES+ Sbjct: 567 DITNYIVEKRESGSTAW-QLINSSVKRTSLFVSHLTKYMQYTFRVSAENNFGVSKATESE 625 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 ++ E T P PPT P + + +N + W P DGG+ + GY I ++ +W+ Sbjct: 626 TIVAEHPFTPPGPPTRP-SVFNITANTMTLKWEEPYHDGGSKVTGYWIEKKERNNILWVR 684 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 K+ + L E Y R+YA N GLS+ E+ + Sbjct: 685 ENKIPCFECNYRAESLVEGLEYQFRVYAMNSAGLSKASEASK 726 Score = 98.7 bits (235), Expect = 2e-18 Identities = 81/319 (25%), Positives = 140/319 (43%), Gaps = 17/319 (5%) Query: 523 DGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G +V+F C +E Y ++TW+ ++ S +++ Y+D VA + I ++ D GT+ Sbjct: 3199 EGDSVKFVCNIENYDSTTEVTWYCGVRQLEASDKYEIAYED-GVAVITINKITRADDGTY 3257 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 C N G S+ EL V + + T A +L+ PP F+ Sbjct: 3258 RCKIVNEYGEDSAYAELFVTG-VRLYRDYFTSRVVKKTKRRVDTARMLQK-PPEFTLPLV 3315 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYCSVLKITNV 700 + G D+ + P+P + W G++++P ++ SD +Y L I N+ Sbjct: 3316 NRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFISDKGLY--QLIIHNL 3373 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-----LKSMIVRQGESVILS 755 + Y+VVA NR GE S L + K + P L ++ ++G+ V Sbjct: 3374 DAEDDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFE 3433 Query: 756 AQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 +V G+ PT+ W K+ P+ ++ +G + I ++ +D GVY + A NS G Sbjct: 3434 IRVSGH--PTLRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAG 3491 Query: 813 IAETSAVITVEEPTEENAE 831 A A + VE T E Sbjct: 3492 SASCQATLKVERVTHVKKE 3510 Score = 97.9 bits (233), Expect = 3e-18 Identities = 135/620 (21%), Positives = 232/620 (37%), Gaps = 35/620 (5%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNI-TTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 I+DA E E ++ S + PLK+ T + + ++ G PQPK+ W Sbjct: 2326 INDAGEA-ETSGILMLEAAPSFHPDYPLKDTYCTGLGTTLRIHVVYIGRPQPKIMWLHGA 2384 Query: 1520 KKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 K L+ T + T Y+ N G +T+ V I KP Sbjct: 2385 KTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHNHFGRADTAFNVEIYDKPDRP 2444 Query: 1575 ISNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 D K+ V W G I K+ +K + E ++ TS R+ Sbjct: 2445 RGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEWELVSSSINGTSC-RV 2503 Query: 1633 KELKRSHSSKYTIEASNTAGTSS-VEVTLKVY-----DKPSKPEGPVIMREISRESVTIE 1686 L S + + A N G S +E+T + +KPS P P++ I+++S + Sbjct: 2504 PNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPSPPLCPIVSG-ITKDSCVVS 2562 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV---ETYCIQKLNENCEYMFRVIA 1743 WKPP+ DGG ++ Y +E D W + V D + ++ L E EY+FRV Sbjct: 2563 WKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVFRVKC 2622 Query: 1744 QNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 +N G S+ + E+ I A+++ + P++ + Sbjct: 2623 ENLGGQSDYSEETLSIHPAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKW 2682 Query: 1803 K---VEIKQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 EI +GKK K I ++ + ++I A N+ G+ S D Sbjct: 2683 LRRGKEIHSDGKKIKIQEFKGGYHQLVISEVDEEDSTVYQIRATNQGGSICATISLDVEV 2742 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 K P + + V +K P P+ + + +++ Sbjct: 2743 PAKIHLPKNLKDKEAIPALRGEVVNIKI--PFVGKPDPVITWQKGQDLIDSNGHYQVIVT 2800 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 +++KD + + A+N G+ + Q+V L+ A VP PP ++ + Sbjct: 2801 RSFTSLVFPSGVEKKDAGFYIVCAKNRFGI----DQQTVELDV-ADVPDPPRG-VKASDI 2854 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 + V +W P DGG+ ++ Y I T W V + + + +L +Y Sbjct: 2855 SRDSVTLNWVAPANDGGSRVISYIIEKCPTTAERWQRVAQ--SRDTHYTVINLFGGTSYQ 2912 Query: 2039 IRIYARNEIGLSEPLESDEP 2058 R+ A N+ G S P E+ P Sbjct: 2913 FRVIAENKFGQSAPSETSGP 2932 Score = 88.2 bits (209), Expect = 2e-15 Identities = 48/167 (28%), Positives = 83/167 (49%), Gaps = 2/167 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 I+ G +V + + Y+ P+P+ W+ ++ +K+ + + A+L IK V + G Y Sbjct: 92 IRLGHNVHIELPYKGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKY 151 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 L L+N ++V L PS P G + E+ + SI I WDEP + G I Y V Sbjct: 152 TLTLDNKVNRRSFHIHVITLGPPSKPVGPIRLDEVRADSIMISWDEPNDDGGGDITCYTV 211 Query: 1418 EYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 E ++ + W ++ ++ TQ + NL Y+F+ YA N +S+ Sbjct: 212 EKRDTSQSNWKMACSHVQDTQFKVLNLIKGVQYQFKVYAENRYGVSE 258 Score = 82.6 bits (195), Expect = 1e-13 Identities = 56/204 (27%), Positives = 100/204 (49%), Gaps = 10/204 (4%) Query: 1866 PSQPRNFVVSESTSR-SVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923 P +PR ++ ++ + SV + W P +GG ITNYI+E + +G W ++V+ + Sbjct: 2441 PDRPRGPIILDALLKNSVIISWKPPTDDGGCMITNYIVEKHEDKEGGEW-ELVSSSINGT 2499 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNI 1982 + N+ + FR+ A+N G S P E S + ++ PSPP P+ + + + Sbjct: 2500 SCRVPNLTDSAGYFFRVYAQNRYGNSEPLELTSPILIKSQLEKPSPPLCPI-VSGITKDS 2558 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK---FNIRDLSENHTYMI 2039 + SW P DGG+ + Y + ++ K W E V + +K F+++ L+E Y+ Sbjct: 2559 CVVSWKPPISDGGSKIKSYCLEMKYKDKREWSEWTPVTTDEIKQTVFSVKCLTEGVEYVF 2618 Query: 2040 RIYARNEIGLSEPLESDEPFKVIP 2063 R+ N G S+ S+E + P Sbjct: 2619 RVKCENLGGQSD--YSEETLSIHP 2640 Score = 79.4 bits (187), Expect = 1e-12 Identities = 52/202 (25%), Positives = 88/202 (43%), Gaps = 8/202 (3%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTK 781 +K K + P + + + + + G+ I+ Q++G P P I W K + + Sbjct: 2241 IKTKLSVECQPSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMS 2300 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 SDG HS++I+ ++ +DEG YT KA N G AETS ++ +E + + PL Sbjct: 2301 SDGRNHSLSIITDQQ-EDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDYPLKDTYCTG 2359 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + T+++ P P I W + + +E IT L+I NV + Sbjct: 2360 LGT----TLRIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHG 2415 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G Y+ N G++ V I Sbjct: 2416 GKYRIRLHNHFGRADTAFNVEI 2437 Score = 78.6 bits (185), Expect = 2e-12 Identities = 124/610 (20%), Positives = 234/610 (38%), Gaps = 45/610 (7%) Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 ++ + S + E+S VE+ E P +N+ +TV ++ V +P PS Sbjct: 4045 SVSVKESTTLVESSTA--VEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPS 4102 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ITW + +I+ S + L I++V + D G Y + N+AGK +TI Sbjct: 4103 ITWIHDGAVITSSAHHHIFSTQYDSHLEISSV-TMADEGSYMVLVENAAGKQEAHFTLTI 4161 Query: 924 -----DVEKVTFVKHLQKSYETEEGKTV--ILECQTSHTVSTKWYHN-KKEISGMDHREI 975 + VT + + ET K+ + Q + K K +SG ++ Sbjct: 4162 FKAESTEQVVTPTRVMSPETETPFSKSPDPVRSPQRVRSPDPKSPQRVKSPVSGKTTPKL 4221 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035 + + D E + + V E + E Sbjct: 4222 PGLKSPPPSDKAPITSSVKSPKRVMSPDPEKKSSISVGPN-KEITSSHSQLTIAEGQSLT 4280 Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC------ 1089 L I ++ + W +G+ + ++Y + G + L I + S H +G+ +C Sbjct: 4281 LSARIPGASS-IRWLLNGKELS-NSDQYRYGVSGANQNLTIMSVSHHHQGKITCEAETAE 4338 Query: 1090 -ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI 1146 ++R + T T P +++ ++Q V +G F E++ G+ + W KD I Sbjct: 4339 GLVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVS-GEPFPDIEWLKDNMPI 4397 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA-------ILTVEEPSIN 1197 S++I+L+ L+I++ D+G+Y+ + N +C+A LT E + Sbjct: 4398 NVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMM 4457 Query: 1198 FTLRLPEFILVPANTDAYLTVEI-----PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 L+ + ++ E+ P + + D + +S + + Sbjct: 4458 MVLQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSES 4517 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF----PPKIVDYEREYRIKRGSDVTLL 1308 ++ T Q + V A++++ L+ E PPKI + ++ G +TL Sbjct: 4518 MV--SMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLS 4575 Query: 1309 VDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + P P +WI +I + K + + ++L I V+ DAG Y L L N G Sbjct: 4576 GAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTLMLTNEFG 4635 Query: 1368 HADVEMNVTI 1377 +NV I Sbjct: 4636 SDTATVNVHI 4645 Score = 77.0 bits (181), Expect = 5e-12 Identities = 81/381 (21%), Positives = 149/381 (39%), Gaps = 18/381 (4%) Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 W +P G S I Y++E +++ EW + + ++ LK +S FR A NE Sbjct: 1 WLKPSYDGGSIISDYIIE-KKLKDEEWSLGGTSRQCEFEVKKLKEHSEVFFRVAARNEKG 59 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + + ++ E P ++ ++ + + G P+P + W +D Sbjct: 60 QGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHNVHIELPYKGKPKPSMLWLKDNL 119 Query: 1521 KLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS---CVVGIQQKPVI 1573 LK ++ EN+ Y N +G KPV Sbjct: 120 PLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIHVITLGPPSKPVG 179 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRI 1632 I ++++ + W G ++ Y + + + + + + ++ Sbjct: 180 PIRLDEVR-ADSIMISWDEPNDDGG---GDITCYTVEKRDTSQSNWKMACSHVQDTQFKV 235 Query: 1633 KELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 L + ++ + A N G S S V K +P P G ++ ++ + +TI+W+ Sbjct: 236 LNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPVVYNVTSDGMTIQWE 295 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 P+ DGG + + +EK E ++ W KV + Y I L E EY FRV AQN G Sbjct: 296 KPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFRVYAQNDAG 355 Query: 1749 FSE-ALESEPIVIKTALDVPS 1768 FS ES+P + + + P+ Sbjct: 356 FSRIGDESKPTMAVSPVASPN 376 Score = 73.3 bits (172), Expect = 7e-11 Identities = 66/297 (22%), Positives = 119/297 (40%), Gaps = 15/297 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +P++Q V EG ++ C + P PDI WL +N+ + + S++ + CS Sbjct: 4357 PHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWL--------KDNMPINVSSNIKLSCS 4408 Query: 694 V----LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L+I NV G YTV A N G+ S L + T +EP +++ L++ + Sbjct: 4409 QNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMVLQTETISTA 4468 Query: 750 ESVILS---AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 S+ S +V G P + ++ ++ V +K Sbjct: 4469 GSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSESMVSMTSSSQMK 4528 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 + AE S+ + + PP + Q + V+E T+ L + +P P + W Sbjct: 4529 KMSVFSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQW 4588 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + + I E + + +I + + E D+G Y + +N G + V I Sbjct: 4589 IHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTLMLTNEFGSDTATVNVHI 4645 Score = 72.5 bits (170), Expect = 1e-10 Identities = 90/382 (23%), Positives = 154/382 (40%), Gaps = 32/382 (8%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDE 800 + + +G+S+ LSA++ G +I W N K + G ++TI+ + Sbjct: 4271 LTIAEGQSLTLSARIPG--ASSIRWLLNGKELSNSDQYRYGVSGANQNLTIMSVSH-HHQ 4327 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 G T +AE +EG+ TV T ++ P F+++ + V E +K V+ P Sbjct: 4328 GKITCEAETAEGLVRCQFDTTV---TTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEP 4384 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---- 916 P I W ++N I+ S I + ++L I NV + DSG Y A N G+ S Sbjct: 4385 FPDIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAA-DSGKYTVKAKNEFGQCSATSS 4443 Query: 917 -HGARVT---------IDVEKVTFVKHLQKSYETEE--GKTVILECQTSH-TVSTKWYHN 963 H +T + E ++ +QKS+ E GK + +S + + K+ + Sbjct: 4444 LHVHTLTQEPMEMMMVLQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLID 4503 Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL 1023 K+ S M ++ E V +T + + + P+ Sbjct: 4504 KRSESSMS--AMMSESMVSMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGSPPKIKSLS 4561 Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 Q+ V+E L + + A +V W G+ I ++ +Y E I L I Sbjct: 4562 QNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEG 4621 Query: 1083 DEGEYSCILRDE--SCTAEVTV 1102 D G Y+ +L +E S TA V V Sbjct: 4622 DAGAYTLMLTNEFGSDTATVNV 4643 Score = 72.1 bits (169), Expect = 2e-10 Identities = 79/326 (24%), Positives = 132/326 (40%), Gaps = 33/326 (10%) Query: 498 FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 F+ + S AP F+ + R ++ +G V+F C+V G P P I W + I S + + Sbjct: 4345 FDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWLKDNMPINVSSNIK 4404 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617 + NV L I V D+G +T AKN G S+T+ L V + M V Sbjct: 4405 LSC-SQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMVLQTE 4463 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 G P K + D S P A F ++ + Sbjct: 4464 TISTAGSIQKSFSG--PEVHGKAFPMHADSSS-------------PSAAAKFLIDK-RSE 4507 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL-PIVLKIKTGEKEPPQ 736 ++S + M S+ + +KK V + E +SL + ++K G PP+ Sbjct: 4508 SSMSAMMSESM---VSMTSSSQMKKMS------VFSHAEASSSLQTLSSELKMG--SPPK 4556 Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITI-LK 793 + ++M V +G+++ LS G+P P + W + + P + + + T T+ + Sbjct: 4557 IKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRIS 4616 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAV 819 K D G YTL N G ++T+ V Sbjct: 4617 AVKEGDAGAYTLMLTNEFG-SDTATV 4641 Score = 66.5 bits (155), Expect = 8e-09 Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 27/292 (9%) Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF-- 1286 W K ++++E+ K TL+I+ ++++ +YT L + + + V+ Sbjct: 114 WLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDNKVNRRSFHIHVITLGP 173 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P K V R ++ S +++ + +PND+ + K + K A Sbjct: 174 PSKPVGPIRLDEVRADS---IMISWD---EPNDDGGGDITCYTVEKRDTSQSNWKMACSH 227 Query: 1347 IK----KVENTDAGI---YKLRLENNCGHADVEMNVTILDK-----PSPPGKPNILEIDS 1394 ++ KV N G+ +K+ EN G ++ ++ ++ K P PPGKP + + S Sbjct: 228 VQDTQFKVLNLIKGVQYQFKVYAENRYGVSEPLISQMVIAKHQFRPPGPPGKPVVYNVTS 287 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452 + I W++P G + I + VE +E+++ W V I +T+ I L Y FR Sbjct: 288 DGMTIQWEKPIYDGGTPIQGFHVEKKEMNSIMWQKVNTMLIKETEYRILGLIEGLEYSFR 347 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNITTEPNEDIEL 1501 YA N+ S + E + + + SP +E + + +T + ++I L Sbjct: 348 VYAQNDAGFSRIGD--ESKPTMAVSPVASPNIEFGPEYFEGLTVKAGDNIRL 397 Score = 64.5 bits (150), Expect = 3e-08 Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 10/203 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+ K+ G +++C+++ P PDI W G+EIV ++ + H Sbjct: 2251 PSLRKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHS--- 2307 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESV 752 L I ++ EG YT A+N GEA +L ++ P PLK + G ++ Sbjct: 2308 -LSIITDQQEDEGEYTCKAINDAGEAETSGILMLEAAPSFHPDY--PLKDTYCTGLGTTL 2364 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE---GVYTLKAEN 809 + +G P+P I W K ++ + T T L K V+ G Y ++ N Sbjct: 2365 RIHVVYIGRPQPKIMWLHGAKTLENTEDITIETTEHYTHLIIKNVQRRVHGGKYRIRLHN 2424 Query: 810 SEGIAETSAVITVEEPTEENAEP 832 G A+T+ + + + + P Sbjct: 2425 HFGRADTAFNVEIYDKPDRPRGP 2447 Score = 62.9 bits (146), Expect = 9e-08 Identities = 56/204 (27%), Positives = 91/204 (44%), Gaps = 10/204 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F ++ + V S+ L C++ P+P + WL +G+EI D + I+ Y Sbjct: 2649 PAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGK-KIKIQEFKGGY-H 2706 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESV 752 L I+ V + Y + A N+ G I L ++ K P+ ++ +++ +GE V Sbjct: 2707 QLVISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIHLPKNLKDKEAIPALRGEVV 2766 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKV--KDEGVYTLKAEN 809 + VG P P ITW K + + T S T ++ P V KD G Y + A+N Sbjct: 2767 NIKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYIVCAKN 2826 Query: 810 SEGIAETSAVITVEEPTEENAEPP 833 GI + TVE + +PP Sbjct: 2827 RFGIDQQ----TVELDVADVPDPP 2846 Score = 62.5 bits (145), Expect = 1e-07 Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 11/209 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + EG + L R+ I WL G+E+ + + L I +V Sbjct: 4273 IAEGQSLTLSARIPGASS--IRWLLNGKELSNSDQYRYGVSGANQN----LTIMSVSHHH 4326 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 +G T A EG + T P + +S V +G++V + +V G P P Sbjct: 4327 QGKITCEAETAEGLVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFP 4386 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITV 822 I W K+N P+ + ++ L+ V D G YT+KA+N G ++ + V Sbjct: 4387 DIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHV 4446 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIK 851 T+E E + + Q T+ G+I+ Sbjct: 4447 HTLTQEPMEMMMVL---QTETISTAGSIQ 4472 Score = 61.7 bits (143), Expect = 2e-07 Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 20/165 (12%) Query: 1047 VVWERDGEIIKP--KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100 V W + G+ + P KY F + +L I N D+ EYS + R ++SC A + Sbjct: 3339 VTWHKSGQKLIPGLDDKKYTFISDKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKARL 3398 Query: 1101 TVVELP--------PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152 TVV P P L N + +G FEI ++ G +RW KDG+ + F I Sbjct: 3399 TVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFEIRVS-GHPTLRWEKDGAPLAFGPSI 3457 Query: 1153 QLTIDGKKQ-KLKIYDCDLDDAGEY----SCEVGNSKCTAILTVE 1192 ++ +G L + D +D+G Y + G++ C A L VE Sbjct: 3458 EVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAGSASCQATLKVE 3502 Score = 61.7 bits (143), Expect = 2e-07 Identities = 72/325 (22%), Positives = 114/325 (35%), Gaps = 14/325 (4%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G+P KP + V+ G + C + P P I W+ G I + + Sbjct: 4069 GVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVITSSAHHHIF----STQ 4124 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 Y S L+I++V EG+Y V+ N G+ L I E QV+ P + M Sbjct: 4125 YDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAE-STEQVVTPTRVMSPETET 4183 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 S V +P+ + P + S T + LK D+ T ++ Sbjct: 4184 PFSKSPDPVRSPQ-RVRSPDPKSPQRVKSPVSGKTTPKLPGLKSPPPSDKAPITSSVKSP 4242 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 + + N E + ++T+ E ++ L AR+ SI W N Sbjct: 4243 KRVMSPDPEKKSSISVGPNKE---ITSSHSQLTIAEGQSLTLSARIP--GASSIRWLLNG 4297 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKV 928 + +S S+ G N L I +V S G C A + G + VT Sbjct: 4298 KELSNSDQYRYGVSGANQNLTIMSV-SHHHQGKITCEAETAEGLVRCQFDTTVTTSHSAA 4356 Query: 929 TFVKHLQKSYETEEGKTVILECQTS 953 +S EG+ V C+ S Sbjct: 4357 PHFLSQPRSQNVVEGQNVKFTCEVS 4381 Score = 60.5 bits (140), Expect = 5e-07 Identities = 57/211 (27%), Positives = 100/211 (47%), Gaps = 17/211 (8%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-NKPVKALPTK-----SDGD 785 ++PP+ PL + GE + + +P P +TW K+ K + L K SD Sbjct: 3305 QKPPEFTLPLVNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFISDKG 3364 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE---PPLFINRFQEI 842 + + I+ +D+ Y++ A N G A +TV P + A+ P+F + Sbjct: 3365 LYQL-IIHNLDAEDDAEYSVVARNRYGEDSCKARLTV-VPRPKPADLTLRPMFKRLLANL 3422 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG-ENIELVITNVDSEIDS 901 KE ++ RV+ + P++ W ++ ++ +I +G + L + +V E DS Sbjct: 3423 ECKEGQDVRFEIRVSGH--PTLRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPE-DS 3479 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 G Y+ A+NSAG +S + T+ VE+VT VK Sbjct: 3480 GVYRVTATNSAGSAS--CQATLKVERVTHVK 3508 Score = 56.0 bits (129), Expect = 1e-05 Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 4/128 (3%) Query: 476 DENNYTQYLQKKLNEKIDK--LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 D+ Y+ + + E K L V +P + ++ P+F L +G V+FE +V Sbjct: 3377 DDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLRPMFKRLLANLECKEGQDVRFEIRV 3436 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G+P + W + A + ++ ++ + L +R+V PED+G + A N+AG AS Sbjct: 3437 SGHPT--LRWEKDGAPLAFGPSIEVVHEGLDYFILHVRDVLPEDSGVYRVTATNSAGSAS 3494 Query: 594 STTELIVE 601 L VE Sbjct: 3495 CQATLKVE 3502 Score = 54.4 bits (125), Expect = 3e-05 Identities = 66/291 (22%), Positives = 119/291 (40%), Gaps = 35/291 (12%) Query: 723 IVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT-ITWCKNNKPVKALPTK 781 +V K+K E V ++ +V++G+SV + T +TW + ++A Sbjct: 3174 LVAKVKIAPYENGPVGGLIRHAVVKEGDSVKFVCNIENYDSTTEVTWYCGVRQLEASDKY 3233 Query: 782 SDGDTHSITILKPKKVK--DEGVYTLKAENSEG----IAE-------------TSAVITV 822 + ++ K+ D+G Y K N G AE TS V+ Sbjct: 3234 EIAYEDGVAVITINKITRADDGTYRCKIVNEYGEDSAYAELFVTGVRLYRDYFTSRVVKK 3293 Query: 823 EEPTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-- 876 + + A +PP F T ++ +T +P P +TW+++ + + P Sbjct: 3294 TKRRVDTARMLQKPPEFTLPLVNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLD 3353 Query: 877 -ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKV 928 + T D +L+I N+D+E D +Y VA N G+ S AR+T+ D+ Sbjct: 3354 DKKYTFISDKGLYQLIIHNLDAE-DDAEYSVVARNRYGEDSCKARLTVVPRPKPADLTLR 3412 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979 K L + E +EG+ V E + S + +W + ++ E++ EG Sbjct: 3413 PMFKRLLANLECKEGQDVRFEIRVSGHPTLRWEKDGAPLAFGPSIEVVHEG 3463 Score = 53.6 bits (123), Expect = 6e-05 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 2/96 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P PR S+ + SVTL W P ++GGS + +YIIE + W + V H + Sbjct: 2843 PDPPRGVKASDISRDSVTLNWVAPANDGGSRVISYIIEKCPTTAERWQR-VAQSRDTH-Y 2900 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 + N+ FR+ AEN G S P+E+ + K Sbjct: 2901 TVINLFGGTSYQFRVIAENKFGQSAPSETSGPVMTK 2936 Score = 52.4 bits (120), Expect = 1e-04 Identities = 60/327 (18%), Positives = 122/327 (37%), Gaps = 18/327 (5%) Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 L+ IP + + W + +++++ + L I + Q + TC A+ Sbjct: 4281 LSARIPGAS-SIRWLLNGKELSNSDQYRYGVSGANQNLTIMSVSHHHQGKITCEAETAEG 4339 Query: 1276 TTKLKVEVV-----EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + + + P + R + G +V + P P+ EW+ ++ I Sbjct: 4340 LVRCQFDTTVTTSHSAAPHFLSQPRSQNVVEGQNVKFTCEVSGEPFPDIEWLKDNMPINV 4399 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN-I 1389 + K S L I V D+G Y ++ +N G ++ + P + + Sbjct: 4400 SSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFGQCSATSSLHVHTLTQEPMEMMMV 4459 Query: 1390 LEIDS----SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN--L 1443 L+ ++ SI + PE G + ++ I ++ + + + Sbjct: 4460 LQTETISTAGSIQKSFSGPEVHGKAFPMHADSSSPSAAAKFLIDKRSESSMSAMMSESMV 4519 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELT 1502 SS + + +V S A ++ + E K+ SP K L +N+ E + + L+ Sbjct: 4520 SMTSSSQMKKMSV----FSHAEASSSLQTLSSELKMGSPPKIKSLSQNMGVEEGQTLTLS 4575 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATY 1529 F G P P V W G+++ T + Y Sbjct: 4576 GAFSGDPAPLVQWIHSGQRIPTEEKRY 4602 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +CQ+ G P P I W+ I S+ +QM D N + +I + ED G +TC Sbjct: 2265 GQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNHSLSIITDQ-QEDEGEYTC 2323 Query: 584 VAKNAAGFASSTTELIVEAPLSDH 607 A N AG A ++ L++EA S H Sbjct: 2324 KAINDAGEAETSGILMLEAAPSFH 2347 Score = 50.8 bits (116), Expect = 4e-04 Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 3/115 (2%) Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMI-VRQGESVILSAQVVGNPRPTIT 767 V +N GE S P E P V + LK I +R G S+ LS +V G P P IT Sbjct: 1139 VNINGTGEFSEPCAAAEPVERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAIT 1198 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 W K+ + +T + I+ D G YT+ AENS G E + ++ V Sbjct: 1199 WSKSETDLHNRGFIEVTNTSTTLIIDKVHRYDAGKYTVVAENSAGKQEANILVKV 1253 Score = 50.0 bits (114), Expect = 7e-04 Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 11/183 (6%) Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDGEIIKPKKNK 1062 +ET +VV E+I E K + L++ E + + E+ PK Sbjct: 3819 RETGARVVVSESIESEYLTAFTSEYIPKPIKKLQMPEPTKSSLSLAKAAKTEVTLPK--- 3875 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122 DF R RK +R E ++ ES T ++L P I R+++ +V+ G+ Sbjct: 3876 IDFASRYAERKQALRTERKSAEKKF------ESMTQPPFSLDLTPRITVRMRSHRVSYGS 3929 Query: 1123 KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 +F + + K + + WF +G E+ S+ ++ L+I +C DD+G Y Sbjct: 3930 STSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVLTLQINNCVADDSGAYRVICK 3989 Query: 1182 NSK 1184 N+K Sbjct: 3990 NAK 3992 Score = 50.0 bits (114), Expect = 7e-04 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 3/125 (2%) Query: 478 NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSM--APIFVEKLRPKHTPDGSTVQFECQVEG 535 + Y + Q E+ FE T S+ P ++R GS+ F V+ Sbjct: 3880 SRYAERKQALRTERKSAEKKFESMTQPPFSLDLTPRITVRMRSHRVSYGSSTSFTLNVQA 3939 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 P P+ITWF + S + M + V TL I +D+G + + KNA G S Sbjct: 3940 KPEPEITWFHNGKELHQSSKYHM-SNISGVLTLQINNCVADDSGAYRVICKNAKGETSDY 3998 Query: 596 TELIV 600 L V Sbjct: 3999 ATLDV 4003 Score = 48.4 bits (110), Expect = 0.002 Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMY 559 P + + AP F E+LR S C++ G P+P + W R+ I + ++ Sbjct: 2640 PAAAIEIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQ 2699 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 LVI EV ED+ + A N G +T L VE P H Sbjct: 2700 EFKGGYHQLVISEVDEEDSTVYQIRATNQGGSICATISLDVEVPAKIH 2747 Score = 48.4 bits (110), Expect = 0.002 Identities = 41/188 (21%), Positives = 73/188 (38%), Gaps = 8/188 (4%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGD 785 E P E L++M V+ + L ++ G P+P + W + K + K + G Sbjct: 2645 EIRAPAFKEELRNMSVKYKSNAALVCKITGQPKPVVKWLRRGKEIHSDGKKIKIQEFKGG 2704 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 H + I + + +D VY ++A N G + + VE P + + P + + I Sbjct: 2705 YHQLVISEVDE-EDSTVYQIRATNQGGSICATISLDVEVPAKIHL--PKNLKDKEAIPAL 2761 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 + + P P ITW + ++I + LV + + D+G Y Sbjct: 2762 RGEVVNIKIPFVGKPDPVITWQKGQDLIDSNGHYQVIVTRSFTSLVFPSGVEKKDAGFYI 2821 Query: 906 CVASNSAG 913 A N G Sbjct: 2822 VCAKNRFG 2829 Score = 48.0 bits (109), Expect = 0.003 Identities = 34/157 (21%), Positives = 65/157 (41%), Gaps = 5/157 (3%) Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX--XXXADILEGI 632 P A F ++ + ++ +E +V S +M+V +++ G Sbjct: 4494 PSAAAKFLIDKRSESSMSAMMSESMVSMTSSSQMKKMSVFSHAEASSSLQTLSSELKMGS 4553 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + V+EG + L P P + W+ G+ I P E +E+ + Sbjct: 4554 PPKIKSLSQNMGVEEGQTLTLSGAFSGDPAPLVQWIHSGQRI-PTEEKRYRVENSTDI-- 4610 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 S L+I+ VK+ G YT++ N G + + + I++ Sbjct: 4611 STLRISAVKEGDAGAYTLMLTNEFGSDTATVNVHIRS 4647 Score = 47.2 bits (107), Expect = 0.005 Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Query: 809 NSEGIAETSAVITVEEPTE--ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G E S EP E E + L + + I ++ G+++L +VT PVP+ITW Sbjct: 1140 NINGTGEFSEPCAAAEPVERIETPDVELADDLKKTICLRAGGSLRLSVKVTGRPVPAITW 1199 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ + I + L+I V D+G Y VA NSAGK V + Sbjct: 1200 SKSETDLHNRGFI--EVTNTSTTLIIDKV-HRYDAGKYTVVAENSAGKQEANILVKV 1253 Score = 46.8 bits (106), Expect = 0.007 Identities = 58/252 (23%), Positives = 95/252 (37%), Gaps = 38/252 (15%) Query: 480 YTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539 +T + KK ++D + +KP P F L + G ++F + +P P Sbjct: 3286 FTSRVVKKTKRRVDTARMLQKP--------PEFTLPLVNRTAYIGEDLRFGVTITVHPDP 3337 Query: 540 QITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 ++TW + + P D + Y D + L+I + ED ++ VA+N G S Sbjct: 3338 RVTWHKSGQKLIPGLDDKKYTFISDKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKAR 3397 Query: 598 L-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 L +V P AD+ + P F + EG D+ E R Sbjct: 3398 LTVVPRP--------------------KPADLT--LRPMFKRLLANLECKEGQDVRFEIR 3435 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + P + W G + +I V E + +L + +V G Y V A N Sbjct: 3436 VSG--HPTLRWEKDGAPLAFGPSIEVVHEG---LDYFILHVRDVLPEDSGVYRVTATNSA 3490 Query: 717 GEASLPIVLKIK 728 G AS LK++ Sbjct: 3491 GSASCQATLKVE 3502 Score = 46.4 bits (105), Expect = 0.009 Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 7/129 (5%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARV 856 ++ ++ ++A NS G +E ++T E+ P + + + I V T++L + Sbjct: 1422 EQYLFRIRAINSRGASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPI 1481 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVI--TNVDSEIDSGDYKCVASNSAGK 914 P P +WY I ++ I G+ +LVI TN+D D+GDY +N+ G Sbjct: 1482 VGRPPPVCSWYFRENRIKITDRIHFKSTGKFSKLVIHDTNID---DTGDYTLEVTNAVGL 1538 Query: 915 SSHGARVTI 923 S +V I Sbjct: 1539 ISEVIKVII 1547 Score = 46.0 bits (104), Expect = 0.011 Identities = 44/155 (28%), Positives = 70/155 (45%), Gaps = 8/155 (5%) Query: 697 ITNVKKFQEGTYTVVAVNREGE---ASLPIVLKIKTGEKEPPQVIEP-LKSMI-VRQGES 751 +TN+ + +E + V+A N G A +P + + + P +EP K + VRQG Sbjct: 1813 LTNMPQGEEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVRQGGV 1872 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 V LS + G P+PT W K+ + + S ++K + D G+Y L EN Sbjct: 1873 VRLSVPIRGKPQPTCKWSKDFGALSTNAMIVSTEDVSELVIKGAERSDSGLYDLLLENRV 1932 Query: 812 GIAETSAVITVEEPTEENA-EPPLFINRFQEITVK 845 G + A I V+ +A E PL + +VK Sbjct: 1933 G--KKKAQIKVKVIGRPSAPEGPLVFDDIHANSVK 1965 Score = 44.8 bits (101), Expect = 0.026 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V+F C V+G P P ITW A+I S ++ + + L I V D G++ Sbjct: 4086 GDLVRFSCDVDGDPAPSITWIHDGAVITSSAHHHIFSTQYD-SHLEISSVTMADEGSYMV 4144 Query: 584 VAKNAAG 590 + +NAAG Sbjct: 4145 LVENAAG 4151 Score = 42.7 bits (96), Expect = 0.11 Identities = 53/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%) Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL----PTKSDGDTHSITI 791 +V E +++ G V++S + T KP+K L PTKS S+++ Sbjct: 3809 EVEEKAQTLKRETGARVVVSESIESEYLTAFTSEYIPKPIKKLQMPEPTKS-----SLSL 3863 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN-----AEPPLFINRFQEITVKE 846 K K + V K + + AE + E + E +PP ++ ITV+ Sbjct: 3864 AKAAKTE---VTLPKIDFASRYAERKQALRTERKSAEKKFESMTQPPFSLDLTPRITVRM 3920 Query: 847 KG-------TIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSE 898 + + V P P ITW+ N E+ S+ N G + L I N ++ Sbjct: 3921 RSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGV-LTLQINNCVAD 3979 Query: 899 IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 DSG Y+ + N+ G++S A + + + L+K E Sbjct: 3980 -DSGAYRVICKNAKGETSDYATLDVAGTEYAAFSSLRKDEE 4019 Score = 42.3 bits (95), Expect = 0.14 Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 6/129 (4%) Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE---NDKEYNITT 1623 +Q+ P T+ + + +G++ I P P V W+K+G KL +DK+Y + Sbjct: 3304 LQKPPEFTLPL--VNRTAYIGEDLRFGVTITVHPDPRVTWHKSGQKLIPGLDDKKYTFIS 3361 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 + + I L ++Y++ A N G S + L V +P KP + R Sbjct: 3362 DKGLYQLIIHNLDAEDDAEYSVVARNRYGEDSCKARLTVVPRP-KPADLTLRPMFKRLLA 3420 Query: 1684 TIEWKPPLD 1692 +E K D Sbjct: 3421 NLECKEGQD 3429 Score = 41.9 bits (94), Expect = 0.19 Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 6/120 (5%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIE--PLKSMIVRQGES 751 ++ +K+ E + V A N +G+ + IK + P + P ++ +R G + Sbjct: 38 EVKKLKEHSEVFFRVAARNEKGQGEFVAIGPIKVIDYIITPEANLSEYPDGTLSIRLGHN 97 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809 V + G P+P++ W K+N P+K T + L K V+ +EG YTL +N Sbjct: 98 VHIELPYKGKPKPSMLWLKDNLPLKESEQIRFKKTENKATLMIKNVRKENEGKYTLTLDN 157 Score = 41.9 bits (94), Expect = 0.19 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 17/156 (10%) Query: 697 ITNVKKFQEGTYTVVAVNREGEASLP--IVLKIKTGEKEPPQVIE----PLKSMIVRQGE 750 I + + ++ + + A+N G AS P +V + E+ ++ P K + V G+ Sbjct: 1415 IEKLNESEQYLFRIRAINSRG-ASEPKELVTAVTVQEQRVMPEVDFSAIPQKVINVLAGK 1473 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 ++ L +VG P P +W +K + KS G S ++ + D G YTL+ Sbjct: 1474 TLELDLPIVGRPPPVCSWYFRENRIKITDRIHFKSTG-KFSKLVIHDTNIDDTGDYTLEV 1532 Query: 808 ENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEI 842 N+ G I+E VI + +P E PL RF EI Sbjct: 1533 TNAVGLISEVIKVIILSKPDEPKG--PL---RFDEI 1563 Score = 41.5 bits (93), Expect = 0.25 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V E +G P+P + W + +K S+ + + +N ATL+I+ V E+ G +T Sbjct: 95 GHNVHIELPYKGKPKPSMLWLKDNLPLKESEQIR-FKKTENKATLMIKNVRKENEGKYTL 153 Query: 584 VAKNAAGFASSTTELIVEAPLS 605 N S +I P S Sbjct: 154 TLDNKVNRRSFHIHVITLGPPS 175 Score = 41.5 bits (93), Expect = 0.25 Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 1582 QKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 + H+V G T ++ P PE+ W+ NG +L +Y+++ ++I Sbjct: 3921 RSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVLTLQINNCVADD 3980 Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662 S Y + N G +S TL V Sbjct: 3981 SGAYRVICKNAKGETSDYATLDV 4003 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/113 (23%), Positives = 42/113 (37%) Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 L+++ + + E P KIV+ + G V D P P+ WI + +I Sbjct: 4054 LVESSTAVEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVIT 4113 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 H + L I V D G Y + +EN G + +TI S Sbjct: 4114 SSAHHHIFSTQYDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAES 4166 Score = 41.1 bits (92), Expect = 0.33 Identities = 30/135 (22%), Positives = 57/135 (42%), Gaps = 3/135 (2%) Query: 1559 VETSCVVG-IQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 VE+S V + ++P + I N+ +GD + ++G P P + W +G + + Sbjct: 4055 VESSTAVEKLPERPGVPAKIVNKPHSLTVNMGDLVRFSCDVDGDPAPSITWIHDGAVITS 4114 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 ++I + + S + I + + Y + N AG TL ++ S + Sbjct: 4115 SAHHHIFSTQYDSHLEISSVTMADEGSYMVLVENAAGKQEAHFTLTIFKAESTEQVVTPT 4174 Query: 1676 REISRESVTIEWKPP 1690 R +S E+ T K P Sbjct: 4175 RVMSPETETPFSKSP 4189 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Query: 1100 VTVVE--LPPEI-ITRLQNQKVNKGNKATFEIELT---KGDALVRWFKDGSEIQFSNHIQ 1153 VTV E + PE+ + + + +N T E++L + + W+ + I+ ++ I Sbjct: 1446 VTVQEQRVMPEVDFSAIPQKVINVLAGKTLELDLPIVGRPPPVCSWYFRENRIKITDRIH 1505 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 GK KL I+D ++DD G+Y+ EV N+ Sbjct: 1506 FKSTGKFSKLVIHDTNIDDTGDYTLEVTNA 1535 Score = 39.1 bits (87), Expect = 1.3 Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G ++ G P P V W +G ++ + K Y + S +RI +K + YT+ Sbjct: 4569 GQTLTLSGAFSGDPAPLVQWIHSGQRIPTEEKRYRVENSTDISTLRISAVKEGDAGAYTL 4628 Query: 1646 EASNTAGTSSVEVTLKV 1662 +N G+ + V + + Sbjct: 4629 MLTNEFGSDTATVNVHI 4645 Score = 38.7 bits (86), Expect = 1.7 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GST + + G P P+ITW + +K + D + N ++ ++E D+G + Sbjct: 457 GSTFTIDVPISGRPAPKITWKLEEMRLK-NTDRVSIKEAQNRTSISVKEAMRGDSGKYNL 515 Query: 584 VAKNAAG 590 + +NAAG Sbjct: 516 ILENAAG 522 Score = 38.7 bits (86), Expect = 1.7 Identities = 22/84 (26%), Positives = 38/84 (45%) Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 ++ P+I R +R+ GS + ++ QA P+P W N K + + S S Sbjct: 3910 LDLTPRITVRMRSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGVL 3969 Query: 1344 SLTIKKVENTDAGIYKLRLENNCG 1367 +L I D+G Y++ +N G Sbjct: 3970 TLQINNCVADDSGAYRVICKNAKG 3993 Score = 37.9 bits (84), Expect = 3.0 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 5/127 (3%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEI-TVKEKGTIKLVARV 856 +E + + A N+ G E + V TE P + +++++ TV++ G ++L + Sbjct: 1820 EEFKFRVMACNAGGSGEPAEVPGTVTVTEMLESPDFDLEPKYKDLYTVRQGGVVRLSVPI 1879 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P+ W ++ +S + I D ELVI + DSG Y + N GK Sbjct: 1880 RGKPQPTCKWSKDFGALSTNAMIVSTEDVS--ELVIKGAERS-DSGLYDLLLENRVGKKK 1936 Query: 917 HGARVTI 923 +V + Sbjct: 1937 AQIKVKV 1943 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 4/89 (4%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P + + ++ V GS + A PEP+I W G+E+ ++ S + Sbjct: 3912 LTPRITVRMRSHRVSYGSSTSFTLNVQAKPEPEITWFHNGKELHQSSKYHMSNISGV--- 3968 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEAS 720 L+I N G Y V+ N +GE S Sbjct: 3969 -LTLQINNCVADDSGAYRVICKNAKGETS 3996 Score = 37.9 bits (84), Expect = 3.0 Identities = 18/77 (23%), Positives = 34/77 (44%) Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 T + G P P++ W K+ + ++ + + I + + S KYT++A N G Sbjct: 4377 TCEVSGEPFPDIEWLKDNMPINVSSNIKLSCSQNVLDLEIWNVTAADSGKYTVKAKNEFG 4436 Query: 1653 TSSVEVTLKVYDKPSKP 1669 S +L V+ +P Sbjct: 4437 QCSATSSLHVHTLTQEP 4453 Score = 37.5 bits (83), Expect = 4.0 Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 11/125 (8%) Query: 708 YTVVAVNREGEASLPIV----LKIKTGEKEPP--QVIEPLKS--MIVRQGESVILSAQVV 759 + V+A N S+P ++ KT + EPP Q+ L S ++VR G ++L A V Sbjct: 809 FRVIAKNANQVCSIPSESTGSVQCKT-DFEPPKAQLDSKLMSETVMVRAGSDLVLDAAVG 867 Query: 760 GNPRPTITWCKNNKPVKALPT--KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 G P P W K N+ + T ++ ++K D G Y L +N G Sbjct: 868 GRPEPKAFWSKGNRELDLCEKYHLQYSPTRAMAVIKFCDRDDTGKYILTVKNVSGTKTAE 927 Query: 818 AVITV 822 + V Sbjct: 928 VSVKV 932 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +++ +V G P P ITW + + ++ + TL+I +V DAG +T Sbjct: 1180 GGSLRLSVKVTGRPVPAITWSKSETDLHNRGFIEV---TNTSTTLIIDKVHRYDAGKYTV 1236 Query: 584 VAKNAAG 590 VA+N+AG Sbjct: 1237 VAENSAG 1243 Score = 37.1 bits (82), Expect = 5.3 Identities = 109/504 (21%), Positives = 197/504 (39%), Gaps = 57/504 (11%) Query: 634 PTFSKKPKAQ---YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 P F +PK + V +G + L + P+P W + N + D+ Sbjct: 1853 PDFDLEPKYKDLYTVRQGGVVRLSVPIRGKPQPTCKWSKDFGAL--STNAMIVSTEDV-- 1908 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI--KTGEKEPPQVIEPLKSMIVRQ 748 S L I ++ G Y ++ NR G+ I +K+ + E P V + + + V+ Sbjct: 1909 --SELVIKGAERSDSGLYDLLLENRVGKKKAQIKVKVIGRPSAPEGPLVFDDIHANSVKV 1966 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V + G+ + A T T + ++K K E + + AE Sbjct: 1967 SWKVPIDNG--GSEILGYILERREATRNAWYTVESRITETQVVVKGLKEGTEYHFKVTAE 2024 Query: 809 NSEGIAET--SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVPSIT 865 NS G + + S V + + EPP +IT K ++ L +R + ++T Sbjct: 2025 NSFGFSSSLKSEHPVVPKTPLCSPEPPSTPPEIMDIT---KNSVALAWSRPKDDGGSAVT 2081 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG-DYKCVASNSAGKSSHGA---RV 921 Y I S+T +++ + + + T DS ++ A NS G+S G V Sbjct: 2082 GYFVEYRIVSSDTWSRH-ETQITSTMFTLSGLTPDSEYQFRIFAVNSIGESEAGPVSDSV 2140 Query: 922 T-------------IDVEKVT--FVKHLQKSYETEEGKTVI---LECQTSHTVSTKWYH- 962 T ID+ +VT V ++ E + GK V+ +EC+ S + + W Sbjct: 2141 TCKDPFDKPSQPGEIDIVQVTNNSVAIRWQAPECDGGKEVLGYWVECRKS--IESTWKKC 2198 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEF 1019 NK+ + D + + G I + + T+T + K ++ P Sbjct: 2199 NKQRLKEKDFT-VAGLAEATEYEFRVLAENETG----ISRPRRTATCIKTKLSVECQPSL 2253 Query: 1020 IRKLQDFEVKEKDVAILEVEI-NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIR 1077 +++ + K AI++ +I D+ W G EI++ +K + + R H L I Sbjct: 2254 RKEMDEVTTKLGQPAIMKCQIIGRPVPDIKWYHAGKEIVESRKYQMSSDGRNH--SLSII 2311 Query: 1078 NTSVHDEGEYSCILRDESCTAEVT 1101 DEGEY+C +++ AE + Sbjct: 2312 TDQQEDEGEYTCKAINDAGEAETS 2335 >UniRef50_Q14324 Cluster: Myosin-binding protein C, fast-type; n=24; Euteleostomi|Rep: Myosin-binding protein C, fast-type - Homo sapiens (Human) Length = 1142 Score = 231 bits (564), Expect = 2e-58 Identities = 187/768 (24%), Positives = 335/768 (43%), Gaps = 41/768 (5%) Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 F +KL ++V + L VEI+ + W ++G+ IKP +KY FE G R L I Sbjct: 258 FTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPS-SKYVFENVGKKRILTIN 316 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 ++ D+ Y ++DE C E+ V E P I+T L++Q+V G++ +E+++ A V Sbjct: 317 KCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQV 376 Query: 1138 RWFKDGSEI----QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 W KDG E+ F + DGK+ L D +D G Y +C A L VEE Sbjct: 377 MWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEE 436 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 + + + + V A+ A E+ DE + WYK + +++ T+ + L Sbjct: 437 KQLEVLQDIAD-LTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKL 495 Query: 1254 IIRKCTEDDQCEYTCV-------LLDAK-STTKLKVEVV--EFPPKI-VD-----YEREY 1297 +I +D+ +YT V L AK + ++KVE V + PPKI +D E Sbjct: 496 VIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAI 555 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAG 1356 + G+ + L V P P W+ ++ + T+ +S I+ + D G Sbjct: 556 VVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEG 615 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y +++ N G + + ++D P PP I + + W+ P G + Y+ Sbjct: 616 RYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYL 675 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSS--YRFRAYAVNEVDISDASETTEYYKVI 1474 VE ++ + W+ + T+T+ ++ K Y R +AVN + +S S T+ + I Sbjct: 676 VERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI 735 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG-KKLKTAKATYENRX 1533 T + + + + TT GG+ V + +G ++ A R Sbjct: 736 APTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERC 795 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV------GIQQKPVITISNEDIKQKH--K 1585 ++ + N G E + + I + P I + ++Q + K Sbjct: 796 GFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRH-LRQTYIRK 854 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 VG++ + +G P P+V+W K G L+ + ++ T + +V +++ RS S +Y + Sbjct: 855 VGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR-VHVRTSDFDTVFFVRQAARSDSGEYEL 913 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 + + ++V +K P V+++E+ + +EW+ P DDG E+ Y ++K Sbjct: 914 SVQIENMKDTATIRIRVVEKAGPPIN-VMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQK 972 Query: 1706 HEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEA 1752 + W V +R+ T C + L EY FRV +N G S++ Sbjct: 973 ADKKTMEWFNV--YERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDS 1018 Score = 142 bits (345), Expect = 7e-32 Identities = 152/647 (23%), Positives = 269/647 (41%), Gaps = 47/647 (7%) Query: 920 RVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977 + ++V+K F K L +Y+ + G + L + S ++ KW+ N +EI Sbjct: 247 KAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFEN 306 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037 G+ D + VKD++ T L VKE + L+D +V D + Sbjct: 307 VGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMA 366 Query: 1038 VEINSETADVVWERDG-EIIKPK--KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 VE++ E A V+W +DG E+ + K +Y F+K G L + D G Y I Sbjct: 367 VEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGG 426 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 C AE+ V E E++ + + V +A F+ E++ +W+K+G E++ S I + Sbjct: 427 QCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITI 486 Query: 1155 TIDGKKQKLKIYDCDLDDAGEY------------SCEVG--NSKCTAILTVEEPSINFTL 1200 + G+ KL I D +D G+Y S ++ K + E P I+ Sbjct: 487 SHVGRFHKLVIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDC 546 Query: 1201 ---RLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISD-VKKRTLII 1255 I+V A L V I E V TW K V TE T I V + +I Sbjct: 547 SGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVI 606 Query: 1256 RKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQ 1312 +D+ YT + + + + ++VV+ P D RI G D +LV ++ Sbjct: 607 ESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVP----DPPEAVRITSVGEDWAILV-WE 661 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT---DAGIYKLRL--ENNCG 1367 + + + +K K ++ + T E+T + +Y++R+ N G Sbjct: 662 PPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIG 721 Query: 1368 HADVEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + MN +P +P L ++ ++ + W P G I Y+VEY + Sbjct: 722 VSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS 781 Query: 1425 TEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDISDASETTEYYKVIKETKI 1479 EW+ + + + + +++NL T + FR VN + + ++ ++ + KI Sbjct: 782 EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKI 841 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 + P + + + E + L F G P+P+V W + G L T++ Sbjct: 842 RLPRHLR--QTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSR 886 Score = 116 bits (278), Expect = 9e-24 Identities = 107/479 (22%), Positives = 192/479 (40%), Gaps = 35/479 (7%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTI 1645 G++ + I G PPP W K + I + S I+ +R +YTI Sbjct: 560 GNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTI 619 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 + +N G + L+V D P PE V + + + + W+PP+ DGG +T Y +E+ Sbjct: 620 KVTNPVGEDVASIFLQVVDVPDPPEA-VRITSVGEDWAILVWEPPMYDGGKPVTGYLVER 678 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTAL 1764 + + RW+K+ TY K+ E Y RV A N +G S+ ++ ++P + Sbjct: 679 KKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFM----P 734 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXX 1823 P+ + + + + W P + G I Y VE EG ++W Sbjct: 735 IAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 794 Query: 1824 A--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 ++ L FR+ N G + P T +TI + PP + ++ R Sbjct: 795 CGFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRK 854 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKD-EIIFR 1939 V G + N ++ F +GK ++V T GG+ + +++ D + +F Sbjct: 855 V-----------GEQL-NLVVPF---QGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFF 899 Query: 1940 I-------SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEW 1992 + S E + V + + + + P + ++ V + W P+ Sbjct: 900 VRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKD 959 Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 DG + ++GY + D W V + + +T + DL + Y R+Y N GLS+ Sbjct: 960 DGNSEIMGYFVQKADKKTMEWFNVYERNRHT-SCTVSDLIVGNEYYFRVYTENICGLSD 1017 Score = 86.6 bits (205), Expect = 7e-15 Identities = 103/432 (23%), Positives = 166/432 (38%), Gaps = 43/432 (9%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA-GTSSVEVT---LK 1661 WYKNG ++ K I+ + + I +++ YT A G+ S ++ +K Sbjct: 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALGSLSAKLNFLEIK 530 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 V P K E P I + S + T E + G +I P W+K +V Sbjct: 531 VEYVP-KQEPPKIHLDCSGK--TSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFT 587 Query: 1722 ------------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 D ++ I+ E + + NPVG E + +DVP Sbjct: 588 TTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVG-----EDVASIFLQVVDVPD- 641 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ- 1827 + + + W P +GG P+ Y VE K++G ++W + Sbjct: 642 PPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYES 701 Query: 1828 -KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 K+ Y+ R++A N IG S P + + P S+P + +V + T + TLKW Sbjct: 702 TKMIEGILYEMRVFAVNAIGVSQPSMNTKPF---MPIAPTSEPLHLIVEDVTDTTTTLKW 758 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946 P G I Y++E+ + W T ++N+ I+FR+ N Sbjct: 759 RPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIA 818 Query: 1947 GVSLP-TESQSVRLEKHATVPS----PPTAPLEIRMVGS--NIVMTSWGTPE----W-DG 1994 G + P T +Q V + + A P IR VG N+V+ G P W G Sbjct: 819 GRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKG 878 Query: 1995 GAPLLGYNIAIR 2006 GAPL + +R Sbjct: 879 GAPLDTSRVHVR 890 Score = 80.6 bits (190), Expect = 4e-13 Identities = 69/309 (22%), Positives = 124/309 (40%), Gaps = 25/309 (8%) Query: 1282 EVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPS 1337 E+ E PPKI + Y K G + L+V +Q P+P W + + H + S Sbjct: 834 EIAE-PPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTS 892 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 +++ +D+G Y+L ++ + + +++K PP + E+ ++ Sbjct: 893 --DFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNA 950 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456 + W P++ GNS I+ Y V+ + T EW +V + T ++ +L + Y FR Y Sbjct: 951 LVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTE 1010 Query: 1457 NEVDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIELTC 1503 N +SD+ ++ I +T I +P PL + L C Sbjct: 1011 NICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNC 1070 Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 G P+PKV W ++ ++ K Y+ Y C A N+ GE Sbjct: 1071 AVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEA 1130 Query: 1560 ETSCVVGIQ 1568 C + ++ Sbjct: 1131 LAECKLEVR 1139 Score = 62.5 bits (145), Expect = 1e-07 Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 6/136 (4%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 IE+ + +DE + I N VG + S+ L+ VP PP A + I VG + + Sbjct: 606 IESAQREDEGRYTIKVTNPVGEDVA----SIFLQV-VDVPDPPEA-VRITSVGEDWAILV 659 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P +DGG P+ GY + + WM++ + + E Y +R++A N Sbjct: 660 WEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNA 719 Query: 2047 IGLSEPLESDEPFKVI 2062 IG+S+P + +PF I Sbjct: 720 IGVSQPSMNTKPFMPI 735 Score = 58.8 bits (136), Expect = 2e-06 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 MAP F+ L + G + C V G+P+P++ W + I+ F + + V T Sbjct: 1047 MAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKF-LITNYQGVLT 1105 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L IR P DAGT+TC A N G A + +L V P Sbjct: 1106 LNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVP 1141 Score = 53.2 bits (122), Expect = 8e-05 Identities = 43/198 (21%), Positives = 74/198 (37%), Gaps = 7/198 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P ++ L W P +GG P+T Y++E K + W K+ + E Sbjct: 640 PDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFT--ET 697 Query: 1926 CIENIKEKDEIIF--RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 E+ K + I++ R+ A N +GVS P+ + + P+ L + V Sbjct: 698 TYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMP---IAPTSEPLHLIVEDVTDTTT 754 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 W P G + GY + W+ V F +++L + R+ Sbjct: 755 TLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVG 814 Query: 2044 RNEIGLSEPLESDEPFKV 2061 N G +EP +P + Sbjct: 815 VNIAGRTEPATLAQPVTI 832 Score = 49.2 bits (112), Expect = 0.001 Identities = 85/331 (25%), Positives = 127/331 (38%), Gaps = 48/331 (14%) Query: 636 FSKKPKAQY-VDEGSDILLECRLVAIPEPDIA--WLFKGEEIVPDENISVAIESDMHMYC 692 F+KK Y VD G+ I L +V I +PD+ W G+EI P Sbjct: 258 FTKKLDPAYQVDRGNKIKL---MVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKR--- 311 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGES 751 +L I + Y V + + L + KEPP ++ PL+ V G+ Sbjct: 312 -ILTINKCTLADDAAYEVAVKDEKCFTELFV--------KEPPVLIVTPLEDQQVFVGDR 362 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT-------KSDGDTHSITILKPKKVKDEGVYT 804 V ++ +V + W K+ + + K DG H I I +D G Y Sbjct: 363 VEMAVEV-SEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRH-ILIFSDVVQEDRGRYQ 420 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 + + AE + VEE E + ++TVK V+ V Sbjct: 421 VITNGGQCEAE----LIVEEKQLE------VLQDIADLTVKASEQAVFKCEVSDEKVTG- 469 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 WY+N + PS+ IT + G +LVI +V E D GDY V A S A++ Sbjct: 470 KWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPE-DEGDYTFVPDGYA-LGSLSAKLNFL 527 Query: 925 VEKVTFVK-------HLQKSYETEEGKTVIL 948 KV +V HL S +T E V++ Sbjct: 528 EIKVEYVPKQEPPKIHLDCSGKTSENAIVVV 558 Score = 48.8 bits (111), Expect = 0.002 Identities = 53/262 (20%), Positives = 102/262 (38%), Gaps = 22/262 (8%) Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 + W+ G E+ +++ +L ++V + G Y V+ + EA L + Sbjct: 376 VMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIV- 434 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTK 781 E++ +V++ + + V+ E + +V + + T W KN +P K + Sbjct: 435 ------EEKQLEVLQDIADLTVKASEQAVFKCEV-SDEKVTGKWYKNGVEVRPSKRITIS 487 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE---NAEPPLF--- 835 G H + ++ + +DEG YT + + SA + E E EPP Sbjct: 488 HVGRFHKL-VIDDVRPEDEGDYTF-VPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLD 545 Query: 836 -INRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 + E I V ++L +T P P TW + +E+ + +E T+ + + Sbjct: 546 CSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 605 Query: 893 TNVDSEIDSGDYKCVASNSAGK 914 D G Y +N G+ Sbjct: 606 IESAQREDEGRYTIKVTNPVGE 627 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 6/95 (6%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSIT 790 P+ + PL +V G S L+ V G+P+P + W KN + K L T G ++ Sbjct: 1049 PKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQG-VLTLN 1107 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 I +P D G YT +A N G A + V P Sbjct: 1108 IRRPSPF-DAGTYTCRAVNELGEALAECKLEVRVP 1141 Score = 43.6 bits (98), Expect = 0.061 Identities = 45/178 (25%), Positives = 76/178 (42%), Gaps = 21/178 (11%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE-GEASLPI-V 724 W G E+ P + I+++ H L I +V+ EG YT V G S + Sbjct: 471 WYKNGVEVRPSKRITISHVGRFHK----LVIDDVRPEDEGDYTFVPDGYALGSLSAKLNF 526 Query: 725 LKIKTG---EKEPPQVIEPLK------SMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 L+IK ++EPP++ +++V G + L + G P P TW K ++ Sbjct: 527 LEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVF 586 Query: 776 KALPTKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETS---AVITVEEPTE 827 ++ + S +++ + +DEG YT+K N G S V+ V +P E Sbjct: 587 TTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPE 644 Score = 41.1 bits (92), Expect = 0.33 Identities = 19/71 (26%), Positives = 33/71 (46%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + + G P P+V+W KN ++ D ++ IT + + I+ + YT A N Sbjct: 1068 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNEL 1127 Query: 1652 GTSSVEVTLKV 1662 G + E L+V Sbjct: 1128 GEALAECKLEV 1138 Score = 38.3 bits (85), Expect = 2.3 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 10/133 (7%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNP 762 + VV VN G + + T + EPP++ P L+ +R+ GE + L G P Sbjct: 810 FRVVGVNIAGRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKP 869 Query: 763 RPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 RP + W K P+ D ++ ++ D G Y L + E + +T+ T Sbjct: 870 RPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQ-IENMKDTA---T 925 Query: 822 VEEPTEENAEPPL 834 + E A PP+ Sbjct: 926 IRIRVVEKAGPPI 938 >UniRef50_UPI00015A6D36 Cluster: UPI00015A6D36 related cluster; n=2; Danio rerio|Rep: UPI00015A6D36 UniRef100 entry - Danio rerio Length = 2222 Score = 228 bits (557), Expect = 1e-57 Identities = 253/1076 (23%), Positives = 438/1076 (40%), Gaps = 74/1076 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +P +F K+ K Q +EG + L C L P + WL + + P E + Sbjct: 448 VNAVPISFIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMR----- 501 Query: 689 HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 H+ + L I N GTY V ++ +A + KI+T +P + L++ + Sbjct: 502 HIVTILELVIRNPVPEDSGTYICVCEDQSTKADI----KIRT---QPITFKQKLRNQMTE 554 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805 +G SVIL ++ P + W K N +K+ I LK + +D G+Y+ Sbjct: 555 EGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKIRQKGCILELKIFNLTQEDSGLYSC 613 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +E AET+A +TV + P F + E G+I L ++++ P + Sbjct: 614 ASET----AETAANVTV------SGAPATFKQDLKNQEALEGGSITLHCELSKSDAP-VE 662 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + +++I P +G+ ELVI+NV E D+G Y CV G A V + Sbjct: 663 WRKGDKLILPGPRFQMRLNGKTAELVISNVFPE-DAGTYSCVT----GDQKTTAEVKVKR 717 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXX 984 TF K KS E +EG +V L C+ S +W+ ++ + + ++ + Sbjct: 718 LPATF-KATLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAEL 776 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D GV +C+ +Q+T ++ V F ++L++ E E + IL E++ + Sbjct: 777 LIRKAQPEDSGVYRCVCGEQKTEAIIKVNALPITFKQELKNQEGDEGNNVILRCELSKAS 836 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 ADV W + E++ P + KY + G +L IR D G Y C+ D++ A V + Sbjct: 837 ADVEWMKGEEVLTPGE-KYQMRQIGTKLELVIRKAIPEDSGVYICVCPDQTSKATVKINA 895 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P L+NQ+V +GN EL+K A V+W+K + + Q+ I+G+ +L Sbjct: 896 TPITFKQNLRNQEVTEGNTVALRCELSKPGATVKWWKGAEMLLAGDRYQMRIEGRIAELL 955 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I + + +D G YSC G K A + V P I F ++L + N L E+ Sbjct: 956 IKNVNSEDVGSYSCTTGKEKTVAEVKVRVPPITFKVKLKNQEVEEEN-KLTLHCELSKAG 1014 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 V W K + V+ K+ + + R LII +D Y+C+ + K TK V V Sbjct: 1015 CPVEWRKGEEVLRPGYKYQIRENDVARELIIMSAMPEDSGVYSCICGEQK--TKATVRVF 1072 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P + G V L + P W+ + I K + +A Sbjct: 1073 ATPVTFKQNLKNQEAPEGGVVVLHCELSKAGVP-VTWLKGDEEIYSGTKYKIKQEGLAAE 1131 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 L IK V D G Y + + A+V + L + E +++ ++ +P Sbjct: 1132 LHIKNVLPMDVGEYSCIIGDQRTTAEVNVRERPLFFCGELQNQDAEEGETAFLSCELSQP 1191 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 +++ + ++ ++ + Q I +L + S +R A D Sbjct: 1192 AVAVEWKKGAVILK----PSYKFEMKQDGCELQLQINDLTSQDSGAYRCCA-------DG 1240 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 ET +KE + + L+N TE E L C P W + LK Sbjct: 1241 IETRASI-TVKERPL---FFREELQNQETEEGETAFLCCEL-SKPGVPAQWKKGAMLLKN 1295 Query: 1525 A---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 T E N Y+C A G +ET + +++KP+ Sbjct: 1296 GHKYSMTQEGNEVLLQIHDLTSQDSGIYRCCA----GNLETRANIVVKEKPLFFFEELHN 1351 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 +Q + +L + + P EV W K +L +Y + ++I +L S Sbjct: 1352 QQAEEGETAFLCCELSK--PGVEVQWKKGAIRLRPGNKYEMKQDGCKVQLQIHDLTSEDS 1409 Query: 1641 SKYTIEASNTAGTSSV---EVTLKVYDKPSKPEG-----PVIMREISRESVTIEWK 1688 Y + + A T+S+ E++L ++ E ++ E+S+ V+++W+ Sbjct: 1410 GTYKCCSGSLATTASIVVKELSLFFSEELQNHEAEEGKTAILSCELSKPGVSVQWR 1465 Score = 194 bits (472), Expect = 3e-47 Identities = 209/854 (24%), Positives = 357/854 (41%), Gaps = 86/854 (10%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + LR + +G+TV C++ P + W++ ++ +QM + +A L+I+ Sbjct: 900 FKQNLRNQEVTEGNTVALRCELSK-PGATVKWWKGAEMLLAGDRYQMRIEG-RIAELLIK 957 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 V ED G S TT G E TV A++ Sbjct: 958 NVNSEDV-----------GSYSCTT-----------GKEKTV------------AEVKVR 983 Query: 632 IPP-TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMH 689 +PP TF K K Q V+E + + L C L P + W KGEE++ P + E+D+ Sbjct: 984 VPPITFKVKLKNQEVEEENKLTLHCELSKAGCP-VEWR-KGEEVLRPGYKYQIR-ENDV- 1039 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L I + G Y+ + ++ +A++ + P + LK+ +G Sbjct: 1040 --ARELIIMSAMPEDSGVYSCICGEQKTKATVRVFAT-------PVTFKQNLKNQEAPEG 1090 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK 806 V+L ++ P +TW K ++ + + K +G + I K D G Y+ Sbjct: 1091 GVVVLHCELSKAGVP-VTWLKGDEEIYSGTKYKIKQEGLAAELHI-KNVLPMDVGEYSCI 1148 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 G T+A + V E P F Q +E T L +++ P ++ W Sbjct: 1149 I----GDQRTTAEVNVRE------RPLFFCGELQNQDAEEGETAFLSCELSQ-PAVAVEW 1197 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + I+ PS DG ++L I ++ S+ DSG Y+C A ++S +T+ Sbjct: 1198 KKGAVILKPSYKFEMKQDGCELQLQINDLTSQ-DSGAYRCCADGIETRAS----ITVKER 1252 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 + F + LQ ETEEG+T L C+ S V +W + + QEG Sbjct: 1253 PLFFREELQNQ-ETEEGETAFLCCELSKPGVPAQWKKGAMLLKNGHKYSMTQEGNEVLLQ 1311 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G+ +C + ET +VVKE F +L + + +E + A L E++ Sbjct: 1312 IHDLTSQDSGIYRCCAGNLETRANIVVKEKPLFFFEELHNQQAEEGETAFLCCELSKPGV 1371 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 +V W++ ++P NKY+ ++ G +L I + + D G Y C + TA + V EL Sbjct: 1372 EVQWKKGAIRLRPG-NKYEMKQDGCKVQLQIHDLTSEDSGTYKCCSGSLATTASIVVKEL 1430 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 LQN + +G A EL+K V+W K ++ S ++ DG +Q+L+I Sbjct: 1431 SLFFSEELQNHEAEEGKTAILSCELSKPGVSVQWRKGTVLLKLSKRYEIKQDGCQQQLQI 1490 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 ++ D+G Y+C G+ TA L V+E + F L NT E+ + Sbjct: 1491 HELTAQDSGTYTCCAGSLITTASLLVKEKPLFFCDVLQNQEAEEGNT-VIFRCELSKPGV 1549 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 V W K ++++ ++K+ + D K L + + T D Y C +T L V+ Sbjct: 1550 SVQWKKGTALLKPSQKYEIKEDGCKLQLNVHELTAQDSGTYKCCAGSLVTTASLVVK--- 1606 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 ++ + E E G V L + + + +W ++K K + D + L Sbjct: 1607 --EELQNQESE----EGKTVILCCEL-SNTGVSVQWKKGMVLLKPSKKFEIKQDGRQLQL 1659 Query: 1346 TIKKVENTDAGIYK 1359 I ++ D+G YK Sbjct: 1660 QIHELTTQDSGTYK 1673 Score = 192 bits (469), Expect = 7e-47 Identities = 188/748 (25%), Positives = 309/748 (41%), Gaps = 53/748 (7%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 FS++ + +EG +L C L + P + W KG ++ +S E L Sbjct: 1434 FSEELQNHEAEEGKTAILSCEL-SKPGVSVQWR-KGTVLL---KLSKRYEIKQDGCQQQL 1488 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +I + GTYT A + ASL + +++P + L++ +G +VI Sbjct: 1489 QIHELTAQDSGTYTCCAGSLITTASLLV-------KEKPLFFCDVLQNQEAEEGNTVIFR 1541 Query: 756 AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ P ++ W K KP + K DG + + + +D G Y A + Sbjct: 1542 CEL-SKPGVSVQWKKGTALLKPSQKYEIKEDGCKLQLNVHE-LTAQDSGTYKCCAGS--- 1596 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + T++++ EE + +E E T+ L ++ V S+ W + + Sbjct: 1597 LVTTASLVVKEELQNQESE--------------EGKTVILCCELSNTGV-SVQWKKGMVL 1641 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + PS+ DG ++L I + ++ DSG YKC A N +S + + + F K Sbjct: 1642 LKPSKKFEIKQDGRQLQLQIHELTTQ-DSGTYKCCAGNLVTTAS----LMVKEPPIFFRK 1696 Query: 933 HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 +LQ S E EEGK L+C+ S V+ +W + E+ Q G Sbjct: 1697 NLQ-SLEAEEGKMATLKCELSKAGVAVQWKKGTVLLKPGKKYEMKQNGCLLQLQINDLKS 1755 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D G C T+ LVVK F R+LQ+ E A+ E++ A V W R Sbjct: 1756 EDSGSYLCCSGSIMTTASLVVKGLPITFKRELQNQVSIEGGSAVFTCELSKPGAPVEW-R 1814 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 G +I KY G + KL I N D G Y+C +D TAE+TV LP Sbjct: 1815 KGRVILKAGAKYHTTLEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAELTVQGLPATFKA 1874 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 L++Q+V +GN T EL+K V W+K ++ QL K +L I + Sbjct: 1875 TLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKAQSE 1934 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 D+G Y C G K AI+ V I F L + NT A L E+ V W+K Sbjct: 1935 DSGVYRCVCGEQKTEAIIKVNATPITFKQNLRNQEVTEGNTVA-LRCELSKPGATVKWWK 1993 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 ++ E++ + + + L+I+ +D Y+C + K+ ++KV + V Sbjct: 1994 GAEMLLAGERYQMRIEGRIAELLIKNVNSEDVGSYSCTMGKEKTVAEVKVRALP-----V 2048 Query: 1292 DYEREYR---IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 ++RE + K G + P +W I+K + + L I Sbjct: 2049 TFKRELQNEVTKEGGQAVFSCELSK-PGAQVDWRKGRVILKADDKYEMKQEGTFTQLFIH 2107 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVT 1376 VE +DAG Y + +++ A++ + T Sbjct: 2108 NVEPSDAGNYSCKTKDSESTAELTVKAT 2135 Score = 185 bits (451), Expect = 1e-44 Identities = 183/779 (23%), Positives = 320/779 (41%), Gaps = 42/779 (5%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + P TF + + Q V EG+ + L C L + P + W E ++ + + IE + Sbjct: 893 INATPITFKQNLRNQEVTEGNTVALRCEL-SKPGATVKWWKGAEMLLAGDRYQMRIEGRI 951 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVR 747 + L I NV G+Y+ G+ +K++ PP + LK+ V Sbjct: 952 ----AELLIKNVNSEDVGSYSCTT----GKEKTVAEVKVRV----PPITFKVKLKNQEVE 999 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTL 805 + + L ++ P + W K + ++ + D I+ +D GVY+ Sbjct: 1000 EENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKYQIRENDVARELIIMSAMPEDSGVYSC 1058 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 G +T A + V A P F + E G + L +++ VP +T Sbjct: 1059 IC----GEQKTKATVRVF------ATPVTFKQNLKNQEAPEGGVVVLHCELSKAGVP-VT 1107 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + +E I +G EL I NV +D G+Y C+ G A V + Sbjct: 1108 WLKGDEEIYSGTKYKIKQEGLAAELHIKNV-LPMDVGEYSCII----GDQRTTAEVNVRE 1162 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 + F LQ + EEG+T L C+ S V+ +W + E+ Q+G Sbjct: 1163 RPLFFCGELQNQ-DAEEGETAFLSCELSQPAVAVEWKKGAVILKPSYKFEMKQDGCELQL 1221 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G +C ET + VKE F +LQ+ E +E + A L E++ Sbjct: 1222 QINDLTSQDSGAYRCCADGIETRASITVKERPLFFREELQNQETEEGETAFLCCELSKPG 1281 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 W++ ++K +KY + G+ L I + + D G Y C + A + V E Sbjct: 1282 VPAQWKKGAMLLK-NGHKYSMTQEGNEVLLQIHDLTSQDSGIYRCCAGNLETRANIVVKE 1340 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P L NQ+ +G A EL+K V+W K ++ N ++ DG K +L+ Sbjct: 1341 KPLFFFEELHNQQAEEGETAFLCCELSKPGVEVQWKKGAIRLRPGNKYEMKQDGCKVQLQ 1400 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I+D +D+G Y C G+ TA + V+E S+ F+ L T A L+ E+ Sbjct: 1401 IHDLTSEDSGTYKCCSGSLATTASIVVKELSLFFSEELQNHEAEEGKT-AILSCELSKPG 1459 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 + V W K +++ ++++ + D ++ L I + T D YTC +T L V+ Sbjct: 1460 VSVQWRKGTVLLKLSKRYEIKQDGCQQQLQIHELTAQDSGTYTCCAGSLITTASLLVK-- 1517 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 E P D + + G+ V + P + +W + ++K + + D Sbjct: 1518 EKPLFFCDVLQNQEAEEGNTVIFRCELSK-PGVSVQWKKGTALLKPSQKYEIKEDGCKLQ 1576 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICW 1401 L + ++ D+G YK + A + + + ++ S GK IL E+ ++ +++ W Sbjct: 1577 LNVHELTAQDSGTYKCCAGSLVTTASLVVKEELQNQESEEGKTVILCCELSNTGVSVQW 1635 Score = 179 bits (435), Expect = 9e-43 Identities = 232/1082 (21%), Positives = 416/1082 (38%), Gaps = 84/1082 (7%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ IP F+K+ + Q V EG + L C +IP W KG E + S Sbjct: 358 LVRAIPAEFTKELQNQEVKEGESVTLMCE-YSIPGIQFVWR-KGPETLKS---SEKYHMR 412 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 C L I NVK G YT + +++ A++ T P I+ LK+ Sbjct: 413 QRKSCISLAIHNVKPDDSGNYTCICRDQKTMATV-------TVNAVPISFIKELKNQETE 465 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL----KPKKVKDEGVY 803 +G+++ L ++ P + W K + + P + H +TIL + +D G Y Sbjct: 466 EGKTMTLRCELSKAGVP-VEWLKGKQTL--CPGEKYQMRHIVTILELVIRNPVPEDSGTY 522 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 E+ T A I + +P F + + +E ++ L +++ +P Sbjct: 523 ICVCEDQ----STKADIKI------RTQPITFKQKLRNQMTEEGSSVILHCEISKADIP- 571 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W + N ++ E G +EL I N+ E DSG Y C AS +A A VT+ Sbjct: 572 VEWRKGNILLKSGEKYKIRQKGCILELKIFNLTQE-DSGLYSC-ASETA---ETAANVTV 626 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982 TF + L K+ E EG ++ L C+ S + +W K I ++ G+ Sbjct: 627 SGAPATFKQDL-KNQEALEGGSITLHCELSKSDAPVEWRKGDKLILPGPRFQMRLNGKTA 685 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C+ DQ+T+ + VK F L+ EV+E + L E++ Sbjct: 686 ELVISNVFPEDAGTYSCVTGDQKTTAEVKVKRLPATFKATLKSQEVQEGNSVTLNCELSK 745 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 V W + E++K + KY + +L IR D G Y C+ ++ A + V Sbjct: 746 AGGRVEWWKGEEMLKTGE-KYQLRHKEAKAELLIRKAQPEDSGVYRCVCGEQKTEAIIKV 804 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 LP L+NQ+ ++GN EL+K A V W K + Q+ G K + Sbjct: 805 NALPITFKQELKNQEGDEGNNVILRCELSKASADVEWMKGEEVLTPGEKYQMRQIGTKLE 864 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 L I +D+G Y C + A + + I F L + NT A L E+ Sbjct: 865 LVIRKAIPEDSGVYICVCPDQTSKATVKINATPITFKQNLRNQEVTEGNTVA-LRCELSK 923 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V W+K ++ +++ + + + L+I+ +D Y+C K+ ++KV Sbjct: 924 PGATVKWWKGAEMLLAGDRYQMRIEGRIAELLIKNVNSEDVGSYSCTTGKEKTVAEVKVR 983 Query: 1283 V--VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V + F K+ + E ++ + +TL + P EW ++++ + + Sbjct: 984 VPPITFKVKLKNQE----VEEENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKYQIREND 1038 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 + L I D+G+Y CG + V + P K N+ ++ Sbjct: 1039 VARELIIMSAMPEDSGVYSC----ICGEQKTKATVRVFATP-VTFKQNLKNQEA------ 1087 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 PE G +++ + + T W+ + T + + + V +D Sbjct: 1088 ---PE--GGVVVLHCELSKAGVPVT-WLKGDEEIYSGTKYKIKQEGLAAELHIKNVLPMD 1141 Query: 1461 ISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + + S + E ++ + L+N E E L+C P V W + Sbjct: 1142 VGEYSCIIGDQRTTAEVNVRERPLFFCGELQNQDAEEGETAFLSCEL-SQPAVAVEWKKG 1200 Query: 1519 GKKLKTA-KATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 LK + K + Y+C A +ET + ++++P+ Sbjct: 1201 AVILKPSYKFEMKQDGCELQLQINDLTSQDSGAYRCCA----DGIETRASITVKERPL-- 1254 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 E+++ + E P W K L+N +Y++T + +++I + Sbjct: 1255 FFREELQNQETEEGETAFLCCELSKPGVPAQWKKGAMLLKNGHKYSMTQEGNEVLLQIHD 1314 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVY--------DKPSKPEGPVIMREISRESVTIE 1686 L S Y A N +++ V K + + E + E+S+ V ++ Sbjct: 1315 LTSQDSGIYRCCAGNLETRANIVVKEKPLFFFEELHNQQAEEGETAFLCCELSKPGVEVQ 1374 Query: 1687 WK 1688 WK Sbjct: 1375 WK 1376 Score = 178 bits (433), Expect = 2e-42 Identities = 184/731 (25%), Positives = 289/731 (39%), Gaps = 41/731 (5%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T K+ + V EG EC L + W G+ IV ++ I VA E + Sbjct: 4 TIVKRIRTATVLEGESCSFECVLSHDITDEAFWNMNGQLIVSNQRIIVANEGRKY----T 59 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 + I V G V N + E S +L +K ++P +V + ++ GE L Sbjct: 60 MSIEEVMTSDAGE---VVCNIK-ELSCRTMLFVK---EKPVRVFRDMLNVKATPGEDPEL 112 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEG 812 S ++ P T+ W KN + ++ P + H + I+ + D G Y +A+ G Sbjct: 113 SCEIT-KPDATVKWLKNGRQIRVSPKYEITQKDHLVKLIIHNAAIMDSGEYCCEAD---G 168 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 IA T A + V + F +++ +EKG + L TR P ++TW + + Sbjct: 169 IA-TRARLDVRDLQHA------FAKELKDVFAEEKGIVVLECE-TRQPATTVTWLKGLMV 220 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV--EKVTF 930 + + L I N++ DS Y C G A +T+ +KV Sbjct: 221 LRSGHKYIMKKKDVLLTLTIFNLEKS-DSAVYIC----DVGMMQSRALLTVQFSGQKVVI 275 Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987 V L+ E EG+T+I C+ S KWY ++ + D EI+ G Sbjct: 276 VDELEDK-ECLEGETIIFRCRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTFK 334 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G I D+ + L+V+ EF ++LQ+ EVKE + L E + Sbjct: 335 QLARKDTGTIIFEAGDKRSYASLLVRAIPAEFTKELQNQEVKEGESVTLMCEYSIPGIQF 394 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 VW + E +K + KY +R L I N D G Y+CI RD+ A VTV +P Sbjct: 395 VWRKGPETLKSSE-KYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQKTMATVTVNAVPI 453 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 I L+NQ+ +G T EL+K V W K + Q+ +L I + Sbjct: 454 SFIKELKNQETEEGKTMTLRCELSKAGVPVEWLKGKQTLCPGEKYQMRHIVTILELVIRN 513 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 +D+G Y C + A + + I F +L + + L EI + V Sbjct: 514 PVPEDSGTYICVCEDQSTKADIKIRTQPITFKQKLRN-QMTEEGSSVILHCEISKADIPV 572 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287 W K +++ EK+ + L I T++D Y+C A+ T V V P Sbjct: 573 EWRKGNILLKSGEKYKIRQKGCILELKIFNLTQEDSGLYSCASETAE--TAANVTVSGAP 630 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 + G +TL + P EW K+I + ++ K+A L I Sbjct: 631 ATFKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNGKTAELVI 689 Query: 1348 KKVENTDAGIY 1358 V DAG Y Sbjct: 690 SNVFPEDAGTY 700 Score = 173 bits (421), Expect = 4e-41 Identities = 152/592 (25%), Positives = 248/592 (41%), Gaps = 34/592 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESVI 753 L+I + GTY A N ASL + KEPP L+S+ +G+ Sbjct: 1659 LQIHELTTQDSGTYKCCAGNLVTTASLMV--------KEPPIFFRKNLQSLEAEEGKMAT 1710 Query: 754 LSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 L ++ + W K KP K K +G + I K +D G Y Sbjct: 1711 LKCEL-SKAGVAVQWKKGTVLLKPGKKYEMKQNGCLLQLQI-NDLKSEDSGSYLC----C 1764 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G T+A + V+ P F Q E G+ +++ P + W + Sbjct: 1765 SGSIMTTASLVVK------GLPITFKRELQNQVSIEGGSAVFTCELSKPGAP-VEWRKGR 1817 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I+ +G +L I N+ E D+G+Y C +S A +T+ TF Sbjct: 1818 VILKAGAKYHTTLEGRLTKLAINNL-VEGDAGNYTCKTKDSQST----AELTVQGLPATF 1872 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 K KS E +EG +V L C+ S +W+ ++ + + ++ + Sbjct: 1873 -KATLKSQEVQEGNSVTLNCELSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKA 1931 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 D GV +C+ +Q+T ++ V T F + L++ EV E + L E++ A V W Sbjct: 1932 QSEDSGVYRCVCGEQKTEAIIKVNATPITFKQNLRNQEVTEGNTVALRCELSKPGATVKW 1991 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 + E++ + +Y G I +L I+N + D G YSC + E AEV V LP Sbjct: 1992 WKGAEMLLAGE-RYQMRIEGRIAELLIKNVNSEDVGSYSCTMGKEKTVAEVKVRALPVTF 2050 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 LQN+ +G +A F EL+K A V W K ++ + ++ +G +L I++ + Sbjct: 2051 KRELQNEVTKEGGQAVFSCELSKPGAQVDWRKGRVILKADDKYEMKQEGTFTQLFIHNVE 2110 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 DAG YSC+ +S+ TA LTV+ + F L P L E+ + VTW Sbjct: 2111 PSDAGNYSCKTKDSESTAELTVKATPVTFKQNLKN-QEAPEGGVVVLHCELSKAGVPVTW 2169 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 K I K+ + + L I+ D EY+C++ D ++T ++ V Sbjct: 2170 LKGDEEIYSGTKYKIKQEGLAAELHIKNVLPMDVGEYSCIIGDQRTTAEVNV 2221 Score = 147 bits (357), Expect = 3e-33 Identities = 128/478 (26%), Positives = 203/478 (42%), Gaps = 34/478 (7%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +++G+P TF ++ + Q EG + C L + P + W KG I+ + Sbjct: 1775 VVKGLPITFKRELQNQVSIEGGSAVFTCEL-SKPGAPVEWR-KGRVIL---KAGAKYHTT 1829 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + + L I N+ + G YT + + A L T + P LKS V+ Sbjct: 1830 LEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAEL-------TVQGLPATFKATLKSQEVQ 1882 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTL 805 +G SV L+ + + + W K + +K + + +++ + +D GVY Sbjct: 1883 EGNSVTLNCE-LSKAGGRVEWWKGEEMLKTGEKYQLRHKEAKAELLIRKAQSEDSGVYRC 1941 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 G +T A+I V NA P F + V E T+ L +++ P ++ Sbjct: 1942 VC----GEQKTEAIIKV------NATPITFKQNLRNQEVTEGNTVALRCELSK-PGATVK 1990 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W++ E++ E +G EL+I NV+SE D G Y C + GK A V + Sbjct: 1991 WWKGAEMLLAGERYQMRIEGRIAELLIKNVNSE-DVGSYSC----TMGKEKTVAEVKVRA 2045 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 VTF + LQ T+EG + C+ S W + + D E+ QEG Sbjct: 2046 LPVTFKRELQNEV-TKEGGQAVFSCELSKPGAQVDWRKGRVILKADDKYEMKQEGTFTQL 2104 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G C KD E++ L VK T F + L++ E E V +L E++ Sbjct: 2105 FIHNVEPSDAGNYSCKTKDSESTAELTVKATPVTFKQNLKNQEAPEGGVVVLHCELSKAG 2164 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 V W + E I KY ++ G +L+I+N D GEYSCI+ D+ TAEV V Sbjct: 2165 VPVTWLKGDEEIY-SGTKYKIKQEGLAAELHIKNVLPMDVGEYSCIIGDQRTTAEVNV 2221 Score = 94.3 bits (224), Expect = 3e-17 Identities = 96/389 (24%), Positives = 159/389 (40%), Gaps = 35/389 (8%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++G+P TF K+Q V EG+ + L C L + + W +KGEE++ + Sbjct: 1865 VQGLPATFKATLKSQEVQEGNSVTLNCEL-SKAGGRVEW-WKGEEMLKTGEKYQLRHKEA 1922 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L I + G Y V GE ++K+ P + L++ V + Sbjct: 1923 K---AELLIRKAQSEDSGVYRCVC----GEQKTEAIIKVNA---TPITFKQNLRNQEVTE 1972 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 G +V L + + P T+ W K + + A G+ + + I ++ + +K Sbjct: 1973 GNTVALRCE-LSKPGATVKWWKGAEMLLA------GERYQMRI--EGRIAE---LLIKNV 2020 Query: 809 NSEGIAETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 NSE + S + E+ E A P F Q KE G +++ P + Sbjct: 2021 NSEDVGSYSCTMGKEKTVAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSK-PGAQVD 2079 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + I+ + +G +L I NV+ D+G+Y C +S A +T+ Sbjct: 2080 WRKGRVILKADDKYEMKQEGTFTQLFIHNVEPS-DAGNYSCKTKDSEST----AELTVKA 2134 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 VTF ++L K+ E EG V+L C+ S V W +EI +I QEG Sbjct: 2135 TPVTFKQNL-KNQEAPEGGVVVLHCELSKAGVPVTWLKGDEEIYSGTKYKIKQEGLAAEL 2193 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 DVG CI+ DQ T+ + V+ Sbjct: 2194 HIKNVLPMDVGEYSCIIGDQRTTAEVNVR 2222 Score = 49.2 bits (112), Expect = 0.001 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + L+ + +G ++ C++ P + W + +I P FQM + A LVI Sbjct: 633 FKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNG-KTAELVIS 690 Query: 572 EVFPEDAGTFTCV 584 VFPEDAGT++CV Sbjct: 691 NVFPEDAGTYSCV 703 Score = 47.2 bits (107), Expect = 0.005 Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F+++L+ + T +G T+ C++ P + W + + P + +QM + + LVIR Sbjct: 455 FIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMRHIV-TILELVIR 512 Query: 572 EVFPEDAGTFTCVAKN 587 PED+GT+ CV ++ Sbjct: 513 NPVPEDSGTYICVCED 528 Score = 46.0 bits (104), Expect = 0.011 Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 8/106 (7%) Query: 499 EKPTSEEQSMA-PI-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 EK +E + A P+ F +L+ + T +G F C++ P Q+ W + I+K + Sbjct: 2035 EKTVAEVKVRALPVTFKRELQNEVTKEGGQAVFSCELSK-PGAQVDWRKGRVILKADDKY 2093 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 +M + L I V P DAG ++C K+ + ST EL V+A Sbjct: 2094 EMK-QEGTFTQLFIHNVEPSDAGNYSCKTKD----SESTAELTVKA 2134 Score = 41.9 bits (94), Expect = 0.19 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F ++L+ + +G +V C+ P Q W + +K S+ + M ++ L I Sbjct: 366 FTKELQNQEVKEGESVTLMCEYS-IPGIQFVWRKGPETLKSSEKYHMRQRKSCIS-LAIH 423 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELI 599 V P+D+G +TC+ ++ A+ T + Sbjct: 424 NVKPDDSGNYTCICRDQKTMATVTVNAV 451 Score = 41.9 bits (94), Expect = 0.19 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 + ++ F E+L+ +G T C++ P + W + T ++K S+ +++ D Sbjct: 1428 KELSLFFSEELQNHEAEEGKTAILSCELSK-PGVSVQWRKGTVLLKLSKRYEIKQDGCQ- 1485 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPL 604 L I E+ +D+GT+TC AG +T L+V E PL Sbjct: 1486 QQLQIHELTAQDSGTYTC----CAGSLITTASLLVKEKPL 1521 Score = 41.9 bits (94), Expect = 0.19 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 E+L+ + + +G TV C++ + W + ++KPS+ F++ D + L I E+ Sbjct: 1607 EELQNQESEEGKTVILCCELSN-TGVSVQWKKGMVLLKPSKKFEIKQDGRQLQ-LQIHEL 1664 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +D+GT+ C A N +T L+V+ P Sbjct: 1665 TTQDSGTYKCCAGNLV----TTASLMVKEP 1690 Score = 41.5 bits (93), Expect = 0.25 Identities = 19/72 (26%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + LR + +G+TV C++ P + W++ ++ + +QM + +A L+I+ Sbjct: 1961 FKQNLRNQEVTEGNTVALRCELSK-PGATVKWWKGAEMLLAGERYQMRIEG-RIAELLIK 2018 Query: 572 EVFPEDAGTFTC 583 V ED G+++C Sbjct: 2019 NVNSEDVGSYSC 2030 Score = 40.7 bits (91), Expect = 0.43 Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F ++L+ + +G+ V C++ + W + ++ P + +QM + LVIR Sbjct: 811 FKQELKNQEGDEGNNVILRCELSK-ASADVEWMKGEEVLTPGEKYQMRQIGTKLE-LVIR 868 Query: 572 EVFPEDAGTFTCVAKNAAGFAS 593 + PED+G + CV + A+ Sbjct: 869 KAIPEDSGVYICVCPDQTSKAT 890 Score = 39.9 bits (89), Expect = 0.75 Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Query: 499 EKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 +K T+E + + F L+ + +G++V C++ ++ W++ ++K + + Sbjct: 707 QKTTAEVKVKRLPATFKATLKSQEVQEGNSVTLNCELSK-AGGRVEWWKGEEMLKTGEKY 765 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCV 584 Q+ + + A L+IR+ PED+G + CV Sbjct: 766 QLRHKEAK-AELLIRKAQPEDSGVYRCV 792 Score = 38.3 bits (85), Expect = 2.3 Identities = 20/88 (22%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Query: 499 EKPTSEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 EK +E + P F KL+ + + + + C++ P + W + +++P + Sbjct: 974 EKTVAEVKVRVPPITFKVKLKNQEVEEENKLTLHCELSKAGCP-VEWRKGEEVLRPGYKY 1032 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCV 584 Q+ ++D L+I PED+G ++C+ Sbjct: 1033 QIR-ENDVARELIIMSAMPEDSGVYSCI 1059 Score = 37.9 bits (84), Expect = 3.0 Identities = 18/79 (22%), Positives = 41/79 (51%), Gaps = 2/79 (2%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q + F L+ + +G++V C++ ++ W++ ++K + +Q+ + + Sbjct: 1866 QGLPATFKATLKSQEVQEGNSVTLNCELSK-AGGRVEWWKGEEMLKTGEKYQLRHKEAK- 1923 Query: 566 ATLVIREVFPEDAGTFTCV 584 A L+IR+ ED+G + CV Sbjct: 1924 AELLIRKAQSEDSGVYRCV 1942 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F +KLR + T +GS+V C++ P + W + ++K + +++ + L I Sbjct: 544 FKQKLRNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKI-RQKGCILELKIF 601 Query: 572 EVFPEDAGTFTCVAKNAAGFASST 595 + ED+G ++C ++ A A+ T Sbjct: 602 NLTQEDSGLYSCASETAETAANVT 625 >UniRef50_Q4RU89 Cluster: Chromosome 1 SCAF14995, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 1 SCAF14995, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 5505 Score = 227 bits (556), Expect = 2e-57 Identities = 191/754 (25%), Positives = 330/754 (43%), Gaps = 46/754 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ IP TF+++ K EG++++L C L + P + W KGEE++ + + M Sbjct: 946 VQAIPTTFTQQLKNIQAQEGTNVVLRCEL-SKPGIPVEWR-KGEELLKN-----GVRFQM 998 Query: 689 HMYCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + L++ K E G Y+ V +++ A++ I P + +K++ + Sbjct: 999 RRRETTLELLIWKPVPEDSGVYSCVCGHQKSTATVRITAV-------PVTFKQKMKNVQI 1051 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVY 803 +G I ++ ++ W K V K DT + K D +Y Sbjct: 1052 EEGNVAIFRCEL-SKAGQSVEWMKGGDAVIRGGEKYQMRQRDTLLELRISDVKPDDSDIY 1110 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 T N ET+A +TV +A P F + + + V+E ++ L +++ +P Sbjct: 1111 TCICAN----IETTATLTV------HALPVTFKQKLKNVHVEEGNSLTLYCEISKPGIP- 1159 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W R +++ + +EL I +VD E DSG Y CV + K A V + Sbjct: 1160 VEWRRGGDLLENGDKYQIKQREMALELTIRDVDPE-DSGVYTCVCRDQRTK----ATVKV 1214 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS---GMDHREIIQEG 979 +F L KS + EEG +V L C+ S V +W + + +S ++ EG Sbjct: 1215 VAVPASFKVSL-KSQDAEEGTSVSLCCELSKKGVHVQWKRDAQPLSEEMSPGKYQMKVEG 1273 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 + D G C+ D++T+ + VK F R +Q VKE D +L E Sbjct: 1274 KTAQLTIHGVQPEDAGRYSCVAGDEKTTAEVRVKALPVAFKRDIQSVAVKEGDRGVLCGE 1333 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 ++ + W + ++KP + KY+ ++ G + KL I + D G+Y+C + TAE Sbjct: 1334 LSRPGSQAEWRKGRVVLKPGR-KYEMKQEGCLVKLVINHVEESDAGKYTCKTNNSQSTAE 1392 Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 +TV LPP L NQ+V +GN EL+K + V W K ++ + Q+ Sbjct: 1393 LTVHGLPPTFRLPLVNQEVMEGNSVILHCELSKASSWVEWRKGKVLLKHGDKYQVRKKEL 1452 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 + ++KI D + D GEYSC G A +TV+E I F L + V + L E Sbjct: 1453 QVEMKILDLGVSDGGEYSCVCGEQTTRATITVKERPIKFLQELKN-VQVQEGNEVKLRCE 1511 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 I V W K + V+ D EK+ + L+IRKC +D Y+CV + +ST + Sbjct: 1512 ISKAGASVEWKKGEKVLSDGEKYQMKQSGSILELVIRKCQPEDSGTYSCVCAEVRSTATI 1571 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 + + P R + VTL + P EW ++++K+ + + + Sbjct: 1572 IITAI--PITFKQKLRNQEVVEEGSVTLRCELSKAGVP-VEWRKEAQLLKEGEKYQMRQE 1628 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 ++A +TI+ V D G Y + A++++ Sbjct: 1629 GRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKV 1662 Score = 211 bits (515), Expect = 2e-52 Identities = 196/806 (24%), Positives = 348/806 (43%), Gaps = 69/806 (8%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 + + P F++ L+ +G T+ +C++ P + W R +++ ++ +++ + + Sbjct: 2404 KELPPFFIDCLQSVTAHEGDTLSLKCELSK-PGVAVQWKRNKVVLRSNRKYELK-QEGCL 2461 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 L IR + PED G+++C A S+ T +V + D + + Sbjct: 2462 LQLSIRGLTPEDHGSYSCHA------GSAETAALVTVKVRDTATIFSPTE---------- 2505 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 +PP F ++ ++ V+EG L C + +P ++ +K ++V + ++ Sbjct: 2506 ------LPPFFKEELQSLEVEEGGAASLSC---VLSKPGVSVRWKKNKLVLRSSRKYEMK 2556 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 D + L+I +K G+Y+ A + E A + + + PP + L ++ Sbjct: 2557 QDGCLL--QLQIKGLKPEDAGSYSCHAGDAETTAMVAVT-------EVPPFFKKNLINVE 2607 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802 +G L ++ P ++ W KN P++A K DG + + +D G Sbjct: 2608 AEEGGVASLCCEL-SKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQLQV-SDLTPEDTGG 2665 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y+ +AE SE TSAV+ V+E F + Q + +E G + L ++++ V Sbjct: 2666 YSCQAEMSE----TSAVLKVKE------HATFFSSDLQSVEAEESGAVTLCCELSKSGVS 2715 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W +N + S DG ++L I ++ E DSG Y C SAG + A + Sbjct: 2716 GVQWKKNGVPLRVSRKYEMKQDGRLLQLHIKDLTPE-DSGGYSC----SAGNAKTSANLV 2770 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 + F L+ S E EEG + L CQ S S +W N+ + E+ Q+G Sbjct: 2771 VRELPPIFKMSLE-SVEVEEGSSASLRCQLSKPGASVQWKKNRMPLRADGKYEMKQDGCL 2829 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G C TS + VKE P FI +LQ E +E A L E++ Sbjct: 2830 IQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITELQSVEAEEGGAASLCCELS 2889 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 V W+++ I ++Y+ ++ G + +L+I+ D G ++C +A VT Sbjct: 2890 KPGVKVQWKKN-RIPLRGSSRYEMKQEGCLLQLHIQELRPEDGGVFTCQTESAETSASVT 2948 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V E LQ+ K +G A+ EL+K A V+W K+ ++ ++ DG Sbjct: 2949 VKE-------NLQSVKAEEGAAASLCCELSKPGASVQWKKNEVALRAGGRFEMKQDGCLI 3001 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 +L++ D L+D+G YSC G +K +A L V E + FT L + V + A L ++ Sbjct: 3002 QLQVKDLKLEDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQR-VEVEEGSSASLRCQLS 3060 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 + V W K + + K+ + D L I+ +D YTC +A+ T V Sbjct: 3061 KPGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAE--TSGAV 3118 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTL 1307 EV P + + + G V+L Sbjct: 3119 EVKALPTLFITELQSVEAEEGGSVSL 3144 Score = 187 bits (455), Expect = 3e-45 Identities = 250/1214 (20%), Positives = 475/1214 (39%), Gaps = 88/1214 (7%) Query: 502 TSEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 T+E AP F KLR + + +V C++ P + W + ++ S +Q+ Sbjct: 1746 TAELTVRAPPVTFKTKLRSQQVEEEKSVTLSCELSK-PGLGVEWKKGQEQLQNSFKYQIR 1804 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619 + + L I+ D+G ++C G +T ++ V + + + Sbjct: 1805 -NRQGIMELTIKNTQLVDSGLYSC----NYGDVKTTADITVTRKGDPYTPFLFIHFSGAD 1859 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 IP +F K Q EG ++ L C L P + W E+ Sbjct: 1860 QLTNTFC--YSAIPLSFKTGLKNQEAPEGGNVALRCELSRTGVP-VQWFRSENELCHGGR 1916 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKEPPQVI 738 + + ++ + + I N++ G Y+ V ++ A + + EKE Sbjct: 1917 YQMTLRGNV----AEMHIRNIQPEDVGEYSCVFGEQKTTAEVNVRAAASVFFEKE----- 1967 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPK 795 L+S V +G+ V+LS +V P +TW K+N ++ K +G HS+ I K Sbjct: 1968 --LESQAVLEGKPVLLSCEVSSANVP-VTWKKDNVVLEDGGRYILKKEGARHSLEIGK-L 2023 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 +++D G + +T+A + V E + Q++TV V Sbjct: 2024 QLEDAGEFCCITRGK----KTTAQLVVRERVR-------IVTALQDVTVTAGEEANFVCE 2072 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 ++ + W+ + + +E G LV+ E ++G V S Sbjct: 2073 LSHADMAEGVWWLGSSPLQRNEMNQMTCQGRQRRLVLAMTTPE-ETGTVAFVVGEER-TS 2130 Query: 916 SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC-QTSHTVSTKWYHNKKEISGMDHRE 974 +H + + KV F + + EG+T +L C T T W N + + E Sbjct: 2131 AH--LLVVPKPKVLF-EEKPRDLVVMEGETAVLSCVTTDFTSPVTWKCNHVPLRNGNKYE 2187 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034 + +EG+ D G+ C D ++S L V E P F LQ EV+E A Sbjct: 2188 MHKEGKVNLLHIHDADPQDTGIYSCDTGDVQSSARLTVTERPPFFQDGLQSVEVEEGGSA 2247 Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 L E++ V W++D ++ + K++ ++ G +L+IR+ D G Y C Sbjct: 2248 FLCCELSKPGVPVDWKKDRLPLRSSR-KHEIKQDGCFLQLHIRDLKPEDSGSYLCQAGSA 2306 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 TA VTV EL P L++ +V +G+ A+ EL+K A V+W K+ ++ ++ Sbjct: 2307 ETTAVVTVKELRPFFTKELRDLEVEEGSSASLRCELSKPGASVQWKKNRMPLRAGGKFEM 2366 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 DG +L++ D +D+G YSC +++ +++++V+E F + + + Sbjct: 2367 KQDGCLFQLQMKDLVPEDSGSYSCHADSAETSSLVSVKELP-PFFIDCLQSVTAHEGDTL 2425 Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 L E+ + V W + K V+ K+ L + L IR T +D Y+C A+ Sbjct: 2426 SLKCELSKPGVAVQWKRNKVVLRSNRKYELKQEGCLLQLSIRGLTPEDHGSYSCHAGSAE 2485 Query: 1275 STTKLKVEV---------VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 + + V+V E PP + + ++ G +L + P + W N Sbjct: 2486 TAALVTVKVRDTATIFSPTELPPFFKEELQSLEVEEGGAASLSC-VLSKPGVSVRWKKNK 2544 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 +++ + + D L IK ++ DAG Y + G A+ V + + P P Sbjct: 2545 LVLRSSRKYEMKQDGCLLQLQIKGLKPEDAGSYSC----HAGDAETTAMVAVTEVP-PFF 2599 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLK 1444 K N++ +++ + E + + + + +K + Q + +L Sbjct: 2600 KKNLINVEAEEGGVASLCCELSKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQLQVSDLT 2659 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + + A + SET+ KV K + L+++ E + + L C Sbjct: 2660 PEDTGGYSCQA-------EMSETSAVLKV----KEHATFFSSDLQSVEAEESGAVTLCCE 2708 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSC 1563 V W ++G L+ ++ YE + ++ G +TS Sbjct: 2709 LSKSGVSGVQWKKNGVPLRVSR-KYEMKQDGRLLQLHIKDLTPEDSGGYSCSAGNAKTSA 2767 Query: 1564 VVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 + +++ P+ +S E ++ + G + + P V W KN L D +Y + Sbjct: 2768 NLVVRELPPIFKMSLESVEVEE--GSSASLRCQLSK-PGASVQWKKNRMPLRADGKYEMK 2824 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT------LKVYDKPSKPEGPV--I 1674 +++K+L+ S Y+ A + +++V V + EG + Sbjct: 2825 QDGCLIQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITELQSVEAEEGGAASL 2884 Query: 1675 MREISRESVTIEWK 1688 E+S+ V ++WK Sbjct: 2885 CCELSKPGVKVQWK 2898 Score = 185 bits (450), Expect = 1e-44 Identities = 171/663 (25%), Positives = 301/663 (45%), Gaps = 45/663 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+K+ + V+EGS L C L + P + W K + ++ D ++ Sbjct: 2319 PFFTKELRDLEVEEGSSASLRCEL-SKPGASVQW--KKNRMPLRAGGKFEMKQDGCLF-- 2373 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L++ ++ G+Y+ A + E +SL V ++ PP I+ L+S+ +G+++ Sbjct: 2374 QLQMKDLVPEDSGSYSCHADSAE-TSSLVSVKEL------PPFFIDCLQSVTAHEGDTLS 2426 Query: 754 LSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L ++ P + W K NK V + K +G ++I + +D G Y+ A Sbjct: 2427 LKCEL-SKPGVAVQW-KRNKVVLRSNRKYELKQEGCLLQLSI-RGLTPEDHGSYSCHA-- 2481 Query: 810 SEGIAETSAVITVE--------EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 G AET+A++TV+ PTE PP F Q + V+E G L V P Sbjct: 2482 --GSAETAALVTVKVRDTATIFSPTEL---PPFFKEELQSLEVEEGGAASLSC-VLSKPG 2535 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 S+ W +N ++ S DG ++L I + E D+G Y C AG + A V Sbjct: 2536 VSVRWKKNKLVLRSSRKYEMKQDGCLLQLQIKGLKPE-DAGSYSC----HAGDAETTAMV 2590 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980 + F K+L + E EEG L C+ S VS +W N + E+ Q+G Sbjct: 2591 AVTEVPPFFKKNLI-NVEAEEGGVASLCCELSKPGVSVQWKKNGVPLRAGSKYEMKQDGC 2649 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G C + ETS +L VKE F LQ E +E L E+ Sbjct: 2650 LMQLQVSDLTPEDTGGYSCQAEMSETSAVLKVKEHATFFSSDLQSVEAEESGAVTLCCEL 2709 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + S + V W+++G ++ + KY+ ++ G + +L+I++ + D G YSC + +A Sbjct: 2710 SKSGVSGVQWKKNGVPLRVSR-KYEMKQDGRLLQLHIKDLTPEDSGGYSCSAGNAKTSAN 2768 Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 + V ELPP L++ +V +G+ A+ +L+K A V+W K+ ++ ++ DG Sbjct: 2769 LVVRELPPIFKMSLESVEVEEGSSASLRCQLSKPGASVQWKKNRMPLRADGKYEMKQDGC 2828 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 +L++ D +D+G YSC G++ +A + V+E + F L + + A L E Sbjct: 2829 LIQLQMKDLQPEDSGSYSCHAGSAVTSATVAVKELAPFFITEL-QSVEAEEGGAASLCCE 2887 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + + V W K + + + ++ + + L I++ +D +TC A+++ + Sbjct: 2888 LSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHIQELRPEDGGVFTCQTESAETSASV 2947 Query: 1280 KVE 1282 V+ Sbjct: 2948 TVK 2950 Score = 184 bits (449), Expect = 2e-44 Identities = 185/742 (24%), Positives = 322/742 (43%), Gaps = 45/742 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP F ++ EG + L+C L +P +A +K ++V N ++ + + Sbjct: 2406 LPPFFIDCLQSVTAHEGDTLSLKCEL---SKPGVAVQWKRNKVVLRSNRKYELKQEGCLL 2462 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK----IKTGEKEPPQVIEPLKSMIVR 747 L I + G+Y+ A + E A + + ++ I + + PP E L+S+ V Sbjct: 2463 --QLSIRGLTPEDHGSYSCHAGSAETAALVTVKVRDTATIFSPTELPPFFKEELQSLEVE 2520 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYT 804 +G + LS V+ P ++ W KN +++ K DG + I K K +D G Y+ Sbjct: 2521 EGGAASLSC-VLSKPGVSVRWKKNKLVLRSSRKYEMKQDGCLLQLQI-KGLKPEDAGSYS 2578 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A G AET+A++ V E PP F + +E G L +++ P S+ Sbjct: 2579 CHA----GDAETTAMVAVTEV------PPFFKKNLINVEAEEGGVASLCCELSK-PGVSV 2627 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W +N + DG ++L ++++ E D+G Y C A S ++S +V Sbjct: 2628 QWKKNGVPLRAGSKYEMKQDGCLMQLQVSDLTPE-DTGGYSCQAEMS--ETSAVLKVK-- 2682 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VS-TKWYHNKKEISGMDHREIIQEGRXX 982 E TF +S E EE V L C+ S + VS +W N + E+ Q+GR Sbjct: 2683 -EHATFFSSDLQSVEAEESGAVTLCCELSKSGVSGVQWKKNGVPLRVSRKYEMKQDGRLL 2741 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C + +TS LVV+E P F L+ EV+E A L +++ Sbjct: 2742 QLHIKDLTPEDSGGYSCSAGNAKTSANLVVRELPPIFKMSLESVEVEEGSSASLRCQLSK 2801 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 A V W+++ ++ KY+ ++ G + +L +++ D G YSC +A V V Sbjct: 2802 PGASVQWKKNRMPLRAD-GKYEMKQDGCLIQLQMKDLQPEDSGSYSCHAGSAVTSATVAV 2860 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 EL P IT LQ+ + +G A+ EL+K V+W K+ ++ S+ ++ +G + Sbjct: 2861 KELAPFFITELQSVEAEEGGAASLCCELSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQ 2920 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 L I + +D G ++C+ +++ +A +TV+E N + + A L E+ Sbjct: 2921 LHIQELRPEDGGVFTCQTESAETSASVTVKE---NL-----QSVKAEEGAAASLCCELSK 2972 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V W K + + +F + D L ++ +D Y+C AK++ L V Sbjct: 2973 PGASVQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKLEDSGSYSCHAGKAKTSATLAVR 3032 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 E P + ++ GS +L P + +W N ++ + + D Sbjct: 3033 --ELPLFFTRSLQRVEVEEGSSASLRCQLSK-PGVSVQWKKNRMPLRAGRKYEMKQDGCL 3089 Query: 1343 ASLTIKKVENTDAGIYKLRLEN 1364 L IK V + D+G Y N Sbjct: 3090 FELRIKDVLSEDSGSYTCHAGN 3111 Score = 181 bits (441), Expect = 2e-43 Identities = 175/751 (23%), Positives = 314/751 (41%), Gaps = 44/751 (5%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +P TF +K K ++EG+ + C L + + W+ G+ ++ + D Sbjct: 1035 ITAVPVTFKQKMKNVQIEEGNVAIFRCELSKAGQ-SVEWMKGGDAVIRGGEKYQMRQRDT 1093 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L+I++VK YT + N E A+L + P + LK++ V + Sbjct: 1094 LLE---LRISDVKPDDSDIYTCICANIETTATLTV-------HALPVTFKQKLKNVHVEE 1143 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G S+ L ++ P + W + ++ K +TI + +D GVYT Sbjct: 1144 GNSLTLYCEI-SKPGIPVEWRRGGDLLENGDKYQIKQREMALELTI-RDVDPEDSGVYTC 1201 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + T A + V A P F + +E ++ L +++ V + Sbjct: 1202 VCRDQR----TKATVKVV------AVPASFKVSLKSQDAEEGTSVSLCCELSKKGV-HVQ 1250 Query: 866 WYRN----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 W R+ +E +SP + +G+ +L I V E D+G Y CVA G A V Sbjct: 1251 WKRDAQPLSEEMSPGK-YQMKVEGKTAQLTIHGVQPE-DAGRYSCVA----GDEKTTAEV 1304 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGR 980 + V F + +Q S +EG +L + S S +W + + E+ QEG Sbjct: 1305 RVKALPVAFKRDIQ-SVAVKEGDRGVLCGELSRPGSQAEWRKGRVVLKPGRKYEMKQEGC 1363 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G C + +++ L V P F L + EV E + IL E+ Sbjct: 1364 LVKLVINHVEESDAGKYTCKTNNSQSTAELTVHGLPPTFRLPLVNQEVMEGNSVILHCEL 1423 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + ++ V W R G+++ +KY K+ ++ I + V D GEYSC+ +++ A + Sbjct: 1424 SKASSWVEW-RKGKVLLKHGDKYQVRKKELQVEMKILDLGVSDGGEYSCVCGEQTTRATI 1482 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 TV E P + + L+N +V +GN+ E++K A V W K + Q+ G Sbjct: 1483 TVKERPIKFLQELKNVQVQEGNEVKLRCEISKAGASVEWKKGEKVLSDGEKYQMKQSGSI 1542 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 +L I C +D+G YSC + TA + + I F +L +V + L E+ Sbjct: 1543 LELVIRKCQPEDSGTYSCVCAEVRSTATIIITAIPITFKQKLRNQEVVEEGS-VTLRCEL 1601 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 + V W K+ ++++ EK+ + + + + IR T D EY C + A ++ ++K Sbjct: 1602 SKAGVPVEWRKEAQLLKEGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIK 1661 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V + P E E + + D + P +W I+K + ++ Sbjct: 1662 VRAL---PVTFKQEMENLVVKEGDSGEFCCELSKPGAPVDWRKGRVILKPGYKYEMKLEG 1718 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 + L I +E +DAG Y + ++ A++ Sbjct: 1719 RLNKLIINNIEESDAGKYTCKSSDSQSTAEL 1749 Score = 173 bits (422), Expect = 3e-41 Identities = 151/654 (23%), Positives = 285/654 (43%), Gaps = 34/654 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +P +F K+Q +EG+ + L C L + + W + + + +E + + Sbjct: 1217 VPASFKVSLKSQDAEEGTSVSLCCEL-SKKGVHVQWK-RDAQPLSEEMSPGKYQMKVEGK 1274 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L I V+ G Y+ VA G+ +++K P ++S+ V++G+ Sbjct: 1275 TAQLTIHGVQPEDAGRYSCVA----GDEKTTAEVRVKA---LPVAFKRDIQSVAVKEGDR 1327 Query: 752 VILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 +L ++ P W K KP + K +G + I ++ D G YT K Sbjct: 1328 GVLCGEL-SRPGSQAEWRKGRVVLKPGRKYEMKQEGCLVKLVINHVEE-SDAGKYTCKTN 1385 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 NS+ AE +TV + PP F V E ++ L +++ + W + Sbjct: 1386 NSQSTAE----LTV------HGLPPTFRLPLVNQEVMEGNSVILHCELSKAS-SWVEWRK 1434 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 ++ + +E+ I ++ D G+Y CV G+ + A +T+ + Sbjct: 1435 GKVLLKHGDKYQVRKKELQVEMKILDLGVS-DGGEYSCVC----GEQTTRATITVKERPI 1489 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F++ L K+ + +EG V L C+ S S +W +K +S + ++ Q G Sbjct: 1490 KFLQEL-KNVQVQEGNEVKLRCEISKAGASVEWKKGEKVLSDGEKYQMKQSGSILELVIR 1548 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G C+ + ++ +++ F +KL++ EV E+ L E++ V Sbjct: 1549 KCQPEDSGTYSCVCAEVRSTATIIITAIPITFKQKLRNQEVVEEGSVTLRCELSKAGVPV 1608 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W ++ +++K + KY + G ++ IR ++ D GEY+C + + +AE+ V LP Sbjct: 1609 EWRKEAQLLK-EGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPV 1667 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 ++N V +G+ F EL+K A V W K ++ ++ ++G+ KL I + Sbjct: 1668 TFKQEMENLVVKEGDSGEFCCELSKPGAPVDWRKGRVILKPGYKYEMKLEGRLNKLIINN 1727 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 + DAG+Y+C+ +S+ TA LTV P + F +L V L+ E+ L V Sbjct: 1728 IEESDAGKYTCKSSDSQSTAELTVRAPPVTFKTKL-RSQQVEEEKSVTLSCELSKPGLGV 1786 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 W K + ++++ K+ + + L I+ D Y+C D K+T + V Sbjct: 1787 EWKKGQEQLQNSFKYQIRNRQGIMELTIKNTQLVDSGLYSCNYGDVKTTADITV 1840 Score = 169 bits (410), Expect = 1e-39 Identities = 240/1185 (20%), Positives = 450/1185 (37%), Gaps = 103/1185 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E + + F +L+ + + V EC+ P ++TW + ++ S+ + + Sbjct: 551 EIRELQHTFARELKDSRAEEKAKVTLECETRR-PAKRVTWLKGMVELRSSRKY-VIRQKG 608 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 V +L I + D+ + C G S +L V+ Sbjct: 609 AVLSLTINSLEKSDSDIYIC----DVGTMQSRAQLTVQGETWSSSGWTLCCYGRLCKSSR 664 Query: 624 XXADILEGIPPTFSKKPKAQYVDE--------GSDILLECRLVAIPEPDIAWLFKGEEIV 675 D P F K +DE G + CR+ ++ W + Sbjct: 665 NDKDCFIFFPRMFPSGQKVFILDELEDVECLEGDTVTFRCRICPSDYSEVKWYLDETLLY 724 Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP 735 ++ + + + + VL + + GT + A ++ ASL + + P Sbjct: 725 TNDLNEIQLLAGGY---HVLTFRQLARKDTGTISFSAGDKRSYASLLV-------RERRP 774 Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITI 791 +I+ L+ +G ++LS V P I W K+ + ++S G +TI Sbjct: 775 TIIKALEDCEAIEGGGLVLSC-VTSKPCH-IRWYKDGCLMWNSSRYFASRS-GCEARLTI 831 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 + D GVY E S G T AV+TV+ A P F + + +E TI Sbjct: 832 REVGS-NDAGVY----ECSAGSVTTRAVVTVK------AIPAEFTQTLKTVEAREGETIT 880 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 L + P W + E I P + I L I + E DSG+Y C + Sbjct: 881 LTCEYSL-PGVHFHWNKGYESIRPGDRYIMRQRKTVISLTIKTLQPE-DSGEYTCQCRDH 938 Query: 912 AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGM 970 +S + + TF + L K+ + +EG V+L C+ S + +W ++ + Sbjct: 939 RTTAS----LKVQAIPTTFTQQL-KNIQAQEGTNVVLRCELSKPGIPVEWRKGEELLKNG 993 Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030 ++ + D GV C+ Q+++ + + F +K+++ +++E Sbjct: 994 VRFQMRRRETTLELLIWKPVPEDSGVYSCVCGHQKSTATVRITAVPVTFKQKMKNVQIEE 1053 Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 +VAI E++ V W + G+ + KY +R + +L I + D Y+CI Sbjct: 1054 GNVAIFRCELSKAGQSVEWMKGGDAVIRGGEKYQMRQRDTLLELRISDVKPDDSDIYTCI 1113 Query: 1091 LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150 + TA +TV LP +L+N V +GN T E++K V W + G ++ + Sbjct: 1114 CANIETTATLTVHALPVTFKQKLKNVHVEEGNSLTLYCEISKPGIPVEWRRGGDLLENGD 1173 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 Q+ +L I D D +D+G Y+C + + A + V +F + L Sbjct: 1174 KYQIKQREMALELTIRDVDPEDSGVYTCVCRDQRTKATVKVVAVPASFKVSLKSQD-AEE 1232 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIED---TEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 T L E+ + + V W + + + K+ + + K L I +D Y+ Sbjct: 1233 GTSVSLCCELSKKGVHVQWKRDAQPLSEEMSPGKYQMKVEGKTAQLTIHGVQPEDAGRYS 1292 Query: 1268 CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 CV D K+T +++V+ + P + +K G D +L + P EW + Sbjct: 1293 CVAGDEKTTAEVRVKAL--PVAFKRDIQSVAVKEG-DRGVLCGELSRPGSQAEWRKGRVV 1349 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 +K + + + L I VE +DAG Y + N+ A++ ++ G P Sbjct: 1350 LKPGRKYEMKQEGCLVKLVINHVEESDAGKYTCKTNNSQSTAELTVH----------GLP 1399 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 + + + GNS I++ + + EW K + K Q K Sbjct: 1400 PTFRLPLVNQEVM------EGNSVILHCELS-KASSWVEWRKGKVLLKHGDKYQVRKKEL 1452 Query: 1448 SYRFRAYAVNEVDISDAS-----ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 + + D + S +TT +KE I+ + LKN+ + +++L Sbjct: 1453 QVEMKILDLGVSDGGEYSCVCGEQTTRATITVKERPIK---FLQELKNVQVQEGNEVKLR 1509 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX-----XXXXXYKCIAFNDHG 1557 C V W + G+K+ + Y+ + Y C+ Sbjct: 1510 CEISKA-GASVEW-KKGEKVLSDGEKYQMKQSGSILELVIRKCQPEDSGTYSCVC----A 1563 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE----GIPPPEVIWYKNGNKL 1613 EV ++ + I P IT + + +V +E VT E G+P V W K L Sbjct: 1564 EVRSTATIIITAIP-ITFKQK--LRNQEVVEEGSVTLRCELSKAGVP---VEWRKEAQLL 1617 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + ++Y + + + + + I+ + + +Y + A ++ ++V Sbjct: 1618 KEGEKYQMRQEGRAAEMTIRGVTLADGGEYNCSVAMAATSAEIKV 1662 Score = 164 bits (398), Expect = 3e-38 Identities = 156/578 (26%), Positives = 244/578 (42%), Gaps = 42/578 (7%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESD 687 ++ +P F + ++ V EG +L C ++ P W KG ++ P + E Sbjct: 1306 VKALPVAFKRDIQSVAVKEGDRGVL-CGELSRPGSQAEWR-KGRVVLKPGRKYEMKQEG- 1362 Query: 688 MHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 C V L I +V++ G YT N + A L + PP PL + V Sbjct: 1363 ----CLVKLVINHVEESDAGKYTCKTNNSQSTAELTV-------HGLPPTFRLPLVNQEV 1411 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKVKDEGVY 803 +G SVIL ++ + W K +K GD + + + K+ D GV Sbjct: 1412 MEGNSVILHCEL-SKASSWVEWRKGKVLLK------HGDKYQVRKKELQVEMKILDLGVS 1464 Query: 804 TLKAENSE-GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + G T A ITV+E P F+ + + V+E +KL +++ Sbjct: 1465 DGGEYSCVCGEQTTRATITVKE------RPIKFLQELKNVQVQEGNEVKLRCEISKAGA- 1517 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 S+ W + +++S E G +ELVI E DSG Y CV + A + Sbjct: 1518 SVEWKKGEKVLSDGEKYQMKQSGSILELVIRKCQPE-DSGTYSCVCAEVRST----ATII 1572 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 I +TF + L+ EEG +V L C+ S V +W + + + ++ QEGR Sbjct: 1573 ITAIPITFKQKLRNQEVVEEG-SVTLRCELSKAGVPVEWRKEAQLLKEGEKYQMRQEGRA 1631 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G C V TS + V+ F +++++ VKE D E++ Sbjct: 1632 AEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPVTFKQEMENLVVKEGDSGEFCCELS 1691 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 A V W + I+KP KY+ + G + KL I N D G+Y+C D TAE+T Sbjct: 1692 KPGAPVDWRKGRVILKPGY-KYEMKLEGRLNKLIINNIEESDAGKYTCKSSDSQSTAELT 1750 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V P T+L++Q+V + T EL+K V W K ++Q S Q+ Sbjct: 1751 VRAPPVTFKTKLRSQQVEEEKSVTLSCELSKPGLGVEWKKGQEQLQNSFKYQIRNRQGIM 1810 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT 1199 +L I + L D+G YSC G+ K TA +TV +T Sbjct: 1811 ELTIKNTQLVDSGLYSCNYGDVKTTADITVTRKGDPYT 1848 Score = 152 bits (369), Expect = 9e-35 Identities = 149/604 (24%), Positives = 254/604 (42%), Gaps = 43/604 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP F K +EG L C L + P + W G + + + + Sbjct: 2595 VPPFFKKNLINVEAEEGGVASLCCEL-SKPGVSVQWKKNGVPLRAGSKYEMKQDGCLMQ- 2652 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+++++ G Y+ A E A VLK+K + L+S+ + + Sbjct: 2653 ---LQVSDLTPEDTGGYSCQAEMSETSA----VLKVK---EHATFFSSDLQSVEAEESGA 2702 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V L ++ + + W KN P++ K DG + I K +D G Y+ A Sbjct: 2703 VTLCCELSKSGVSGVQWKKNGVPLRVSRKYEMKQDGRLLQLHI-KDLTPEDSGGYSCSAG 2761 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N A+TSA + V E PP+F + + V+E + L ++++ P S+ W + Sbjct: 2762 N----AKTSANLVVREL------PPIFKMSLESVEVEEGSSASLRCQLSK-PGASVQWKK 2810 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N + DG I+L + ++ E DSG Y C AG + A V + Sbjct: 2811 NRMPLRADGKYEMKQDGCLIQLQMKDLQPE-DSGSYSC----HAGSAVTSATVAVKELAP 2865 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F+ LQ S E EEG L C+ S V +W N+ + G E+ QEG Sbjct: 2866 FFITELQ-SVEAEEGGAASLCCELSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHIQ 2924 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D GV C + ETS + VKE LQ + +E A L E++ A V Sbjct: 2925 ELRPEDGGVFTCQTESAETSASVTVKEN-------LQSVKAEEGAAASLCCELSKPGASV 2977 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W+++ E+ +++ ++ G + +L +++ + D G YSC +A + V ELP Sbjct: 2978 QWKKN-EVALRAGGRFEMKQDGCLIQLQVKDLKLEDSGSYSCHAGKAKTSATLAVRELPL 3036 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 LQ +V +G+ A+ +L+K V+W K+ ++ ++ DG +L+I D Sbjct: 3037 FFTRSLQRVEVEEGSSASLRCQLSKPGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKD 3096 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 +D+G Y+C GN++ + + V+ F L + + L ++ + V Sbjct: 3097 VLSEDSGSYTCHAGNAETSGAVEVKALPTLFITEL-QSVEAEEGGSVSLCCQLSKPGVSV 3155 Query: 1228 TWYK 1231 W K Sbjct: 3156 QWKK 3159 Score = 148 bits (358), Expect = 2e-33 Identities = 145/571 (25%), Positives = 243/571 (42%), Gaps = 47/571 (8%) Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT-WYRNN 870 G + ++A +TV+E + + P ++I KE +++L NP P + W++ Sbjct: 79 GKSRSTAQLTVKERPLQVSHP------LEDIDAKENSSVQLSCGF--NPSPRVVRWFKGR 130 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + S + +G EL I + +DSG Y+CVA G + A + ++V + Sbjct: 131 TALKTSNKYSMRREGYRAELTIHGLTG-MDSGQYRCVA----GGAQSTAHLQVEVRTLKL 185 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEI-SGMDHREIIQEGRXXXXXXXX 988 V+HL+ + EE + C+ + ++ +W N + S +R IQ Sbjct: 186 VRHLEP-VDVEEDGSATFSCELNFVIANAEWLLNNVRLYSNAVNR--IQHMGTMHSLTIK 242 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048 VG + S L VKE F++ L+D +E+ L EI+ ETA V Sbjct: 243 KLRPQVGRVTFKAGLLSESAPLKVKERPAVFLKSLEDAVGEEEGEVCLHCEISKETATPV 302 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV----- 1103 W +DG ++ +K++F + G R L IR+ S D G Y+C A+VTV Sbjct: 303 WRKDGSVLTAD-DKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLE 361 Query: 1104 -------------ELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFS 1149 +L I+ RL+ V +G TFE L+ D W +G + Sbjct: 362 NSSFACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATD 421 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 + +Q +G K +L I + L D+G+ + + C +L V+E ++ L VP Sbjct: 422 SRLQAIGNGCKYRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVP 481 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 DA L+ EI + + W K +I + K+ + L+IR T D +Y C Sbjct: 482 GE-DAELSCEITKTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCE 540 Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 S + KVE+ E ++ R + + VTL + + P W+ ++ Sbjct: 541 ADGVAS--RAKVEIRELQHTFARELKDSRAEEKAKVTLECETRR-PAKRVTWLKGMVELR 597 Query: 1330 KCKHTKPSIDSKSA--SLTIKKVENTDAGIY 1358 + K I K A SLTI +E +D+ IY Sbjct: 598 SSR--KYVIRQKGAVLSLTINSLEKSDSDIY 626 Score = 125 bits (301), Expect = 2e-26 Identities = 127/516 (24%), Positives = 213/516 (41%), Gaps = 42/516 (8%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 FS ++ +E + L C L + W G + +S E L Sbjct: 2688 FSSDLQSVEAEESGAVTLCCELSKSGVSGVQWKKNGVPL----RVSRKYEMKQDGRLLQL 2743 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I ++ G Y+ A N + A+L + + PP L+S+ V +G S L Sbjct: 2744 HIKDLTPEDSGGYSCSAGNAKTSANLVV-------RELPPIFKMSLESVEVEEGSSASLR 2796 Query: 756 AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 Q+ P ++ W KN P++A K DG + +K + +D G Y+ A G Sbjct: 2797 CQL-SKPGASVQWKKNRMPLRADGKYEMKQDGCLIQLQ-MKDLQPEDSGSYSCHA----G 2850 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A TSA + V+E P FI Q + +E G L +++ P + W +N Sbjct: 2851 SAVTSATVAVKELA------PFFITELQSVEAEEGGAASLCCELSK-PGVKVQWKKNRIP 2903 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + S +G ++L I + E D G + C ++ +S VT + Sbjct: 2904 LRGSSRYEMKQEGCLLQLHIQELRPE-DGGVFTCQTESAETSAS-----------VTVKE 2951 Query: 933 HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 +LQ S + EEG L C+ S S +W N+ + E+ Q+G Sbjct: 2952 NLQ-SVKAEEGAAASLCCELSKPGASVQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKL 3010 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D G C +TS L V+E F R LQ EV+E A L +++ V W++ Sbjct: 3011 EDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQRVEVEEGSSASLRCQLSKPGVSVQWKK 3070 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 + ++ + KY+ ++ G + +L I++ D G Y+C + + V V LP IT Sbjct: 3071 NRMPLRAGR-KYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAETSGAVEVKALPTLFIT 3129 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ 1147 LQ+ + +G + +L+K V+W K+G ++ Sbjct: 3130 ELQSVEAEEGGSVSLCCQLSKPGVSVQWKKNGMPLR 3165 Score = 120 bits (289), Expect = 4e-25 Identities = 136/571 (23%), Positives = 231/571 (40%), Gaps = 60/571 (10%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDMHMYCSVLKITNVKKFQE 705 E S + L C P P + FKG + N S+ E Y + L I + Sbjct: 107 ENSSVQLSCGFN--PSPRVVRWFKGRTALKTSNKYSMRREG----YRAELTIHGLTGMDS 160 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ---VVGNP 762 G Y VA + A L + E +++ L+ + V + S S + V+ N Sbjct: 161 GQYRCVAGGAQSTAHLQV-------EVRTLKLVRHLEPVDVEEDGSATFSCELNFVIANA 213 Query: 763 RPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSA 818 W NN + + + G HS+TI KK++ + G T KA G+ SA Sbjct: 214 E----WLLNNVRLYSNAVNRIQHMGTMHSLTI---KKLRPQVGRVTFKA----GLLSESA 262 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V+E P +F+ ++ +E+G + L +++ + W ++ +++ + Sbjct: 263 PLKVKE------RPAVFLKSLEDAVGEEEGEVCLHCEISKETATPV-WRKDGSVLTADDK 315 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---------------HGARVTI 923 G+ L+I ++ + D+G Y C S K+ G+ Sbjct: 316 HEFLQFGKARALIIRSLSKD-DAGLYTCDFGTSQTKAKVTVHGECLENSSFACRGSGTKR 374 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRX 981 D+ +T V+ L K+ EG+T EC SH+V + W N + ++ + I G Sbjct: 375 DLH-ITIVQRL-KTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATDSRLQAIGNGCK 432 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G + +KD T+L VKE R L + + + A L EI Sbjct: 433 YRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVPGEDAELSCEIT 492 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 + W +DG +I+ + KY+ ++ KL IRN ++ D G+Y C + A+V Sbjct: 493 KTDVTIRWLKDGRLIR-QSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGVASRAKVE 551 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 + EL L++ + + K T E E + V W K E++ S + G Sbjct: 552 IRELQHTFARELKDSRAEEKAKVTLECETRRPAKRVTWLKGMVELRSSRKYVIRQKGAVL 611 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 L I + D+ Y C+VG + A LTV+ Sbjct: 612 SLTINSLEKSDSDIYICDVGTMQSRAQLTVQ 642 Score = 115 bits (277), Expect = 1e-23 Identities = 136/639 (21%), Positives = 238/639 (37%), Gaps = 56/639 (8%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 W GE + P +++ + +H C +T+ + G VA A L + Sbjct: 37 WTLNGEVLEPSAAVNIDRKGTVHSLC----LTSTESSMCGPVVFVAGKSRSTAQLTV--- 89 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783 ++ P QV PL+ + ++ SV LS +PR + W K +K + + Sbjct: 90 ----KERPLQVSHPLEDIDAKENSSVQLSCGFNPSPR-VVRWFKGRTALKTSNKYSMRRE 144 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G +TI + D G Y A G A+++A + VE T + + + + Sbjct: 145 GYRAELTIHGLTGM-DSGQYRCVA----GGAQSTAHLQVEVRTLK------LVRHLEPVD 193 Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 V+E G+ + + + W NN + + G L I + ++ Sbjct: 194 VEEDGSATFSCELNF-VIANAEWLLNNVRLYSNAVNRIQHMGTMHSLTIKKLRPQVGRVT 252 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYH 962 +K AG S A + + F+K L+ + EEG+ V L C+ S +T W Sbjct: 253 FK------AGLLSESAPLKVKERPAVFLKSLEDAVGEEEGE-VCLHCEISKETATPVWRK 305 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---- 1018 + ++ D E +Q G+ D G+ C +T + V E Sbjct: 306 DGSVLTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLENSSF 365 Query: 1019 --------------FIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKY 1063 +++L+ V E + E ++ D W +G+++ ++ Sbjct: 366 ACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATD-SRL 424 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 G +L I+ + D G+ ++D +C + V E P I L N K G Sbjct: 425 QAIGNGCKYRLTIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLNIKAVPGED 484 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 A E+TK D +RW KDG I+ S ++ + KL I + + D+G+Y CE Sbjct: 485 AELSCEITKTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGV 544 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 A + + E F L + L E VTW K + + K+ Sbjct: 545 ASRAKVEIRELQHTFARELKD-SRAEEKAKVTLECETRRPAKRVTWLKGMVELRSSRKYV 603 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + +L I + D Y C + +S +L V+ Sbjct: 604 IRQKGAVLSLTINSLEKSDSDIYICDVGTMQSRAQLTVQ 642 Score = 98.3 bits (234), Expect = 2e-18 Identities = 105/431 (24%), Positives = 181/431 (41%), Gaps = 44/431 (10%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ +PP F ++ V+EGS L C+L + P + W + D + + Sbjct: 2770 VVRELPPIFKMSLESVEVEEGSSASLRCQL-SKPGASVQWKKNRMPLRADGKYEMKQDG- 2827 Query: 688 MHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 C + L++ +++ G+Y+ A G A + +K + P I L+S+ Sbjct: 2828 ----CLIQLQMKDLQPEDSGSYSCHA----GSAVTSATVAVK---ELAPFFITELQSVEA 2876 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVY 803 +G + L + + P + W KN P++ K +G + I + + +D GV+ Sbjct: 2877 EEGGAASLCCE-LSKPGVKVQWKKNRIPLRGSSRYEMKQEGCLLQLHI-QELRPEDGGVF 2934 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 T + E+ AETSA +TV+E Q + +E L +++ P S Sbjct: 2935 TCQTES----AETSASVTVKE-------------NLQSVKAEEGAAASLCCELSK-PGAS 2976 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W +N + DG I+L + ++ E DSG Y C AGK+ A + + Sbjct: 2977 VQWKKNEVALRAGGRFEMKQDGCLIQLQVKDLKLE-DSGSYSC----HAGKAKTSATLAV 3031 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982 + F + LQ+ E EEG + L CQ S VS +W N+ + E+ Q+G Sbjct: 3032 RELPLFFTRSLQR-VEVEEGSSASLRCQLSKPGVSVQWKKNRMPLRAGRKYEMKQDGCLF 3090 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C + ETS + VK FI +LQ E +E L +++ Sbjct: 3091 ELRIKDVLSEDSGSYTCHAGNAETSGAVEVKALPTLFITELQSVEAEEGGSVSLCCQLSK 3150 Query: 1043 ETADVVWERDG 1053 V W+++G Sbjct: 3151 PGVSVQWKKNG 3161 Score = 85.0 bits (201), Expect = 2e-14 Identities = 112/532 (21%), Positives = 204/532 (38%), Gaps = 40/532 (7%) Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W N E++ PS + + G L +T+ +S + G VA GKS A++T+ Sbjct: 37 WTLNGEVLEPSAAVNIDRKGTVHSLCLTSTESSM-CGPVVFVA----GKSRSTAQLTVK- 90 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984 E+ V H + + +E +V L C + + +W+ + + + + +EG Sbjct: 91 ERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVRWFKGRTALKTSNKYSMRREGYRAEL 150 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G +C+ +++ L V+ + +R L+ +V+E A E+N Sbjct: 151 TIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKLVRHLEPVDVEEDGSATFSCELNFVI 210 Query: 1045 ADVVWERDGEIIKPKKNKYD-FEKRGHIRKLYIRNTSVH-DEGEYSCILRDESCTAEVTV 1102 A+ W + ++ N + + G + L I+ + L ES A + V Sbjct: 211 ANAEWLLNN--VRLYSNAVNRIQHMGTMHSLTIKKLRPQVGRVTFKAGLLSES--APLKV 266 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E P + L++ + + E++K A W KDGS + + + GK + Sbjct: 267 KERPAVFLKSLEDAVGEEEGEVCLHCEISKETATPVWRKDGSVLTADDKHEFLQFGKARA 326 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTV-----EEPS-------------INFTLRLPE 1204 L I DDAG Y+C+ G S+ A +TV E S I RL Sbjct: 327 LIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGECLENSSFACRGSGTKRDLHITIVQRLKT 386 Query: 1205 FILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 ++ T + +L+ + D+ W V+ + I + K L I++ Sbjct: 387 LSVLEGETCTFECHLSHSVDDQP---CWTINGQVVATDSRLQAIGNGCKYRLTIKEAQLS 443 Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 D + + D T L V+ E P I + G D L + W Sbjct: 444 DSGDVVFTIKDLACRTLLFVK--EKPVHIFRDLLNIKAVPGEDAELSCEITK-TDVTIRW 500 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 + + ++I++ + ++ A L I+ D+G Y + A VE+ Sbjct: 501 LKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEADGVASRAKVEI 552 Score = 84.6 bits (200), Expect = 3e-14 Identities = 85/348 (24%), Positives = 133/348 (38%), Gaps = 9/348 (2%) Query: 939 ETEEGKTVILECQTSHTVST--KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 E E + + + +TS +W N + + I ++G G Sbjct: 14 EVMEPEAALFQVETSLRSGRPPRWTLNGEVLEPSAAVNIDRKGTVHSLCLTSTESSMCGP 73 Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 + + ++ L VKE + L+D + KE L N V W + + Sbjct: 74 VVFVAGKSRSTAQLTVKERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVRWFKGRTAL 133 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 K NKY + G+ +L I + D G+Y C+ TA + V +++ L+ Sbjct: 134 KTS-NKYSMRREGYRAELTIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKLVRHLEPV 192 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-QLTIDGKKQKLKIYDCDLDDAGE 1175 V + ATF EL A W + + +SN + ++ G L I G Sbjct: 193 DVEEDGSATFSCELNFVIANAEWLLNNVRL-YSNAVNRIQHMGTMHSLTIKKLR-PQVGR 250 Query: 1176 YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235 + + G +A L V+E F L+ E + + L EI ET W K SV Sbjct: 251 VTFKAGLLSESAPLKVKERPAVF-LKSLEDAVGEEEGEVCLHCEISKETATPVWRKDGSV 309 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 + +K + K R LIIR ++DD YTC S TK KV V Sbjct: 310 LTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDF--GTSQTKAKVTV 355 Score = 83.4 bits (197), Expect = 6e-14 Identities = 120/652 (18%), Positives = 236/652 (36%), Gaps = 30/652 (4%) Query: 1020 IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 +R + EV E + A+ +VE + + W +GE+++P + +++G + L + + Sbjct: 7 VRGMSPVEVMEPEAALFQVETSLRSGRPPRWTLNGEVLEPSA-AVNIDRKGTVHSLCLTS 65 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138 T G + TA++TV E P ++ L++ + + +VR Sbjct: 66 TESSMCGPVVFVAGKSRSTAQLTVKERPLQVSHPLEDIDAKENSSVQLSCGFNPSPRVVR 125 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF 1198 WFK + ++ SN + +G + +L I+ D+G+Y C G ++ TA L VE ++ Sbjct: 126 WFKGRTALKTSNKYSMRREGYRAELTIHGLTGMDSGQYRCVAGGAQSTAHLQVEVRTLKL 185 Query: 1199 TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L E + V + A + E+ + W + + +L I+K Sbjct: 186 VRHL-EPVDVEEDGSATFSCELNFVIANAEWLLNNVRLYSNAVNRIQHMGTMHSLTIKKL 244 Query: 1259 -TEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 + + + LL + K+K F + D E +V L + Sbjct: 245 RPQVGRVTFKAGLLSESAPLKVKERPAVFLKSLEDAVGE----EEGEVCLHCEISK-ETA 299 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W + ++ + K+ +L I+ + DAG+Y + A V ++ Sbjct: 300 TPVWRKDGSVLTADDKHEFLQFGKARALIIRSLSKDDAGLYTCDFGTSQTKAKVTVHGEC 359 Query: 1378 LDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 L+ S G ++ + + G + + + D W + Sbjct: 360 LENSSFACRGSGTKRDLHITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVA 419 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK-----VIKETKIQSPTVEKPLKN 1490 T + +Q + YR + E +SD+ + K + K + + + L N Sbjct: 420 TDSRLQAIGNGCKYRL---TIKEAQLSDSGDVVFTIKDLACRTLLFVKEKPVHIFRDLLN 476 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXX 1546 I P ED EL+C + W +DG+ ++ + +N Sbjct: 477 IKAVPGEDAELSCEITKT-DVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSG 535 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 Y C A + + +Q + + ++K KV E P V W Sbjct: 536 DYCCEADGVASRAKVE-IRELQHTFARELKDSRAEEKAKVTLECETRR-----PAKRVTW 589 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 K +L + ++Y I K + I L++S S Y + + + V Sbjct: 590 LKGMVELRSSRKYVIRQKGAVLSLTINSLEKSDSDIYICDVGTMQSRAQLTV 641 Score = 58.8 bits (136), Expect = 2e-06 Identities = 117/598 (19%), Positives = 210/598 (35%), Gaps = 48/598 (8%) Query: 1109 IITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS--NHIQLTIDGKKQKLKI 1165 I+ L++ + +G+ TF + D + V+W+ D + + + N IQL + G L Sbjct: 685 ILDELEDVECLEGDTVTFRCRICPSDYSEVKWYLDETLLYTNDLNEIQL-LAGGYHVLTF 743 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 D G S G+ + A L V E L + + + + + Sbjct: 744 RQLARKDTGTISFSAGDKRSYASLLVRERRPTIIKALEDCEAIEGG--GLVLSCVTSKPC 801 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 + WYK ++ ++ ++ + L IR+ +D Y C TT+ V V Sbjct: 802 HIRWYKDGCLMWNSSRYFASRSGCEARLTIREVGSNDAGVYECSA--GSVTTRAVVTVKA 859 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P + + + G +TL +Y + P + W + I+ SL Sbjct: 860 IPAEFTQTLKTVEAREGETITLTCEY-SLPGVHFHWNKGYESIRPGDRYIMRQRKTVISL 918 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 TIK ++ D+G Y C D ++ + P L+ NI E Sbjct: 919 TIKTLQPEDSGEY------TCQCRDHRTTASLKVQAIPTTFTQQLK------NIQAQE-- 964 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G + ++ + I EW + + K Q + ++ + D S Sbjct: 965 --GTNVVLRCELSKPGIPV-EWRKGEELLKNGVRFQMRRRETTLELLIWKPVPEDSGVYS 1021 Query: 1466 ETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 + K +I + T ++ +KN+ E C Q V W + G + Sbjct: 1022 CVCGHQKSTATVRITAVPVTFKQKMKNVQIEEGNVAIFRCELSKAGQ-SVEWMKGGDAVI 1080 Query: 1524 TAKATYENRXXXXXXXXXXXX-----XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 Y+ R Y CI N +ET+ + + PV + Sbjct: 1081 RGGEKYQMRQRDTLLELRISDVKPDDSDIYTCICAN----IETTATLTVHALPVTF--KQ 1134 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 +K H L P V W + G+ LEN +Y I +E + I+++ Sbjct: 1135 KLKNVHVEEGNSLTLYCEISKPGIPVEWRRGGDLLENGDKYQIKQREMALELTIRDVDPE 1194 Query: 1639 HSSKYTIEASNTAGTSSVEV-----TLKVYDKPSKPE---GPVIMREISRESVTIEWK 1688 S YT + ++V+V + KV K E + E+S++ V ++WK Sbjct: 1195 DSGVYTCVCRDQRTKATVKVVAVPASFKVSLKSQDAEEGTSVSLCCELSKKGVHVQWK 1252 Score = 51.6 bits (118), Expect = 2e-04 Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 11/198 (5%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAII--- 550 L ++ +S+ + P+F L T G T++ C+V G P P ++WF+ Q++++ Sbjct: 4344 LKELQQRSSQPTNTPPVFESLLSDWTTKIGQTIKLTCKVTGSPTPVVSWFKGQSSLLPLH 4403 Query: 551 -----KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN-AAGFASSTTELIVEAPL 604 + S F +Y + + +V P D ++ S T LI+++ Sbjct: 4404 CTCQPRSSVGFVLYMHSSFTHSYMC-DVRPLDGLPLEDDPRHIILADCSGTCTLILDSLS 4462 Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664 + + A ++ PP F + ++ + +G +I C + P P Sbjct: 4463 AQDSGQYACFAHSFMGSAGTLAKVVVQAPPRFVSRLESACLIKGENIQFSCSTLTTPLPQ 4522 Query: 665 IAWLFKGEEIVPDENISV 682 I W +G E++ E + Sbjct: 4523 IRWSKEGRELIDMEKYCI 4540 Score = 50.8 bits (116), Expect = 4e-04 Identities = 49/184 (26%), Positives = 78/184 (42%), Gaps = 16/184 (8%) Query: 1074 LYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE- 1129 L + + S D G+Y+C + T VV+ PP ++RL++ + KG F Sbjct: 4456 LILDSLSAQDSGQYACFAHSFMGSAGTLAKVVVQAPPRFVSRLESACLIKGENIQFSCST 4515 Query: 1130 LTKGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEV--GNSKC 1185 LT +RW K+G E+ + D + L + D G+Y CE+ C Sbjct: 4516 LTTPLPQIRWSKEGRELIDMEKYCIRNDARSGILSLTVIGATEADIGQYECELMWRTKTC 4575 Query: 1186 -TAILTVEEPSINFTLRLPEFILV-PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 T +L V EP + L E +L+ P T + +P T V + +ED E+ Sbjct: 4576 RTYLLKVGEPDL-----LKEILLMDPFITQSSADQAVPASTGQVL-QQPPCFLEDEEEEI 4629 Query: 1244 LISD 1247 IS+ Sbjct: 4630 YISE 4633 Score = 50.0 bits (114), Expect = 7e-04 Identities = 25/89 (28%), Positives = 50/89 (56%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 EL P IT LQ+ + +G A+ EL++ +W K+ ++ ++ ++ +G +L Sbjct: 3167 ELAPFFITELQSVEAEEGGAASLCCELSRPAVKAQWKKNRIPLRANSRYEMKQEGCLLQL 3226 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 I + +D G YSC+ G+++ +A L+V+ Sbjct: 3227 HIQELRPEDGGSYSCQAGSAETSARLSVK 3255 Score = 48.4 bits (110), Expect = 0.002 Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 31/283 (10%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 I+ IP TF +K + Q V E + L C L P + W + + + E + E Sbjct: 1572 IITAIPITFKQKLRNQEVVEEGSVTLRCELSKAGVP-VEWRKEAQLLKEGEKYQMRQEG- 1629 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + + I V G Y A + + T ++E +++++V+ Sbjct: 1630 ---RAAEMTIRGVTLADGGEYNCSVAMAATSAEIKVRALPVTFKQE-------MENLVVK 1679 Query: 748 QGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G+S + + P + W K KP K +G + + I+ + D G YT Sbjct: 1680 EGDSGEFCCE-LSKPGAPVDWRKGRVILKPGYKYEMKLEGRLNKL-IINNIEESDAGKYT 1737 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 K+ +S+ AE +TV P P F + + V+E+ ++ L +++ P + Sbjct: 1738 CKSSDSQSTAE----LTVRAP------PVTFKTKLRSQQVEEEKSVTLSCELSK-PGLGV 1786 Query: 865 TWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDSGDYKC 906 W + E + S + +N G +EL I N +DSG Y C Sbjct: 1787 EWKKGQEQLQNSFKYQIRNRQG-IMELTIKNTQL-VDSGLYSC 1827 Score = 46.4 bits (105), Expect = 0.009 Identities = 77/398 (19%), Positives = 148/398 (37%), Gaps = 43/398 (10%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 +F++ L + V C++ + W R+ + + D + L+I Sbjct: 272 VFLKSLEDAVGEEEGEVCLHCEISKETATPV-W-RKDGSVLTADDKHEFLQFGKARALII 329 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630 R + +DAG +TC F +S T+ A ++ HG E D+ Sbjct: 330 RSLSKDDAGLYTC------DFGTSQTK----AKVTVHG-ECLENSSFACRGSGTKRDL-- 376 Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 T ++ K V EG EC L + W G+ + D + AI + Sbjct: 377 --HITIVQRLKTLSVLEGETCTFECHLSHSVDDQPCWTINGQVVATDSRLQ-AIGNGC-K 432 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 Y +K + + +T+ + + +L +K ++P + L ++ GE Sbjct: 433 YRLTIKEAQLSDSGDVVFTI------KDLACRTLLFVK---EKPVHIFRDLLNIKAVPGE 483 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAE 808 LS ++ TI W K+ + ++ P ++ +++ ++D G Y +A Sbjct: 484 DAELSCEIT-KTDVTIRWLKDGRLIRQSPKYEMNVVKNLAKLVIRNATIRDSGDYCCEA- 541 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 +G+A + A + + E F ++ +EK + L TR P +TW + Sbjct: 542 --DGVA-SRAKVEIRELQH------TFARELKDSRAEEKAKVTLECE-TRRPAKRVTWLK 591 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 + S G + L I +++ DS Y C Sbjct: 592 GMVELRSSRKYVIRQKGAVLSLTINSLEKS-DSDIYIC 628 Score = 42.3 bits (95), Expect = 0.14 Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 E P FI +LQ E +E A L E++ W+++ I ++Y+ ++ G + + Sbjct: 3167 ELAPFFITELQSVEAEEGGAASLCCELSRPAVKAQWKKN-RIPLRANSRYEMKQEGCLLQ 3225 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 L+I+ D G YSC +A ++V Sbjct: 3226 LHIQELRPEDGGSYSCQAGSAETSARLSV 3254 Score = 41.5 bits (93), Expect = 0.25 Identities = 30/116 (25%), Positives = 46/116 (39%), Gaps = 2/116 (1%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 L+ +D F K + M P+F E + + ST+ C VEG + W + Sbjct: 3771 LDTAVDVQAAF-KSYKTSKDMRPVFSEVFKNQSADLHSTLTLVCVVEGN-LSTVRWLKNG 3828 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + V +LVI+ + D+G +TC A N G S + V P Sbjct: 3829 QSIMNDHRCCSETTETGVCSLVIKNLASTDSGVYTCEAVNKFGITSYNGNITVVQP 3884 Score = 41.1 bits (92), Expect = 0.33 Identities = 22/77 (28%), Positives = 43/77 (55%), Gaps = 6/77 (7%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTR 858 YTL+ +S + +TS + ++E + +++P P+F + + T K TIKL +VT Sbjct: 4327 YTLQGRSS--VVKTSWLKDLKELQQRSSQPTNTPPVFESLLSDWTTKIGQTIKLTCKVTG 4384 Query: 859 NPVPSITWYRNNEIISP 875 +P P ++W++ + P Sbjct: 4385 SPTPVVSWFKGQSSLLP 4401 Score = 40.7 bits (91), Expect = 0.43 Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F +++ +G + +F C++ P + W + I+KP ++M + + L+I Sbjct: 1669 FKQEMENLVVKEGDSGEFCCELSK-PGAPVDWRKGRVILKPGYKYEMKLEG-RLNKLIIN 1726 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + DAG +TC + + + ST EL V AP Sbjct: 1727 NIEESDAGKYTCKSSD----SQSTAELTVRAP 1754 Score = 38.7 bits (86), Expect = 1.7 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELV 891 P+F F+ + T+ LV V N + ++ W +N + I++ ++ + LV Sbjct: 3792 PVFSEVFKNQSADLHSTLTLVCVVEGN-LSTVRWLKNGQSIMNDHRCCSETTETGVCSLV 3850 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 I N+ S DSG Y C A N G +S+ +T+ Sbjct: 3851 IKNLAST-DSGVYTCEAVNKFGITSYNGNITV 3881 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 8/117 (6%) Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 IL +D G Y A + G A T A + V+ P P F++R + + + I Sbjct: 4457 ILDSLSAQDSGQYACFAHSFMGSAGTLAKVVVQAP-------PRFVSRLESACLIKGENI 4509 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYKC 906 + P+P I W + + E D + L +T + +E D G Y+C Sbjct: 4510 QFSCSTLTTPLPQIRWSKEGRELIDMEKYCIRNDARSGILSLTVIGATEADIGQYEC 4566 Score = 38.3 bits (85), Expect = 2.3 Identities = 48/218 (22%), Positives = 92/218 (42%), Gaps = 15/218 (6%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540 S TV++ L+++ E L C P V W ++ L+ A +E + Sbjct: 2946 SVTVKENLQSVKAEEGAAASLCCELSK-PGASVQWKKNEVALR-AGGRFEMKQDGCLIQL 3003 Query: 1541 XXXXXXXYKCIAFNDH-GEVETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEG 1598 +++ H G+ +TS + +++ P+ T S + ++ + G + + Sbjct: 3004 QVKDLKLEDSGSYSCHAGKAKTSATLAVRELPLFFTRSLQRVEVEE--GSSASLRCQLSK 3061 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P V W KN L ++Y + +RIK++ S YT A N + +VEV Sbjct: 3062 -PGVSVQWKKNRMPLRAGRKYEMKQDGCLFELRIKDVLSEDSGSYTCHAGNAETSGAVEV 3120 Query: 1659 ----TLKVYDKPS---KPEGPV-IMREISRESVTIEWK 1688 TL + + S + G V + ++S+ V+++WK Sbjct: 3121 KALPTLFITELQSVEAEEGGSVSLCCQLSKPGVSVQWK 3158 Score = 37.1 bits (82), Expect = 5.3 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 +AP F+ +L+ +G C++ P + W + ++ + ++M + + Sbjct: 3168 LAPFFITELQSVEAEEGGAASLCCELSR-PAVKAQWKKNRIPLRANSRYEMK-QEGCLLQ 3225 Query: 568 LVIREVFPEDAGTFTCVAKNA 588 L I+E+ PED G+++C A +A Sbjct: 3226 LHIQELRPEDGGSYSCQAGSA 3246 >UniRef50_A7RGM2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 545 Score = 224 bits (548), Expect = 2e-56 Identities = 159/554 (28%), Positives = 260/554 (46%), Gaps = 46/554 (8%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD-----GDTHS 788 PP+ L+ + V +G +V L V G+P+P + W K+ KPV LP + G+ ++ Sbjct: 2 PPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYT 61 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + ++K + D G Y KA NS G +S + V + EPP F ++IT+ E Sbjct: 62 L-VIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPK--EPPKFERNLKDITIAEGC 118 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 + + +VT +P P + WY N +++ P + + D E+ L++ + ++ SG Y CVA Sbjct: 119 STRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDL-SGKYTCVA 177 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 N + V + E V + EE + V T ST + Sbjct: 178 ENEVENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVY----TMRDGSTS-------VL 226 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028 +++ E+ E D+G ++C +S ML E P+F+++L+ EV Sbjct: 227 VIENAELDDEAMYTCKAIN-----DLGEVEC------SSEMLPTDEAGPKFLQRLELKEV 275 Query: 1029 KEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 E LEVE++ + VV W +DGE++KP + E G + L I NT++ DEGEY Sbjct: 276 VEGSRTDLEVEVSGKPKPVVEWLKDGELVKPS-SLMTLETEGQVHTLTIMNTTLDDEGEY 334 Query: 1088 SCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWF 1140 +CI +++ SCTAE+ V E PP+ I + + ++ +G A FE ++ V W Sbjct: 335 TCIAKNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWL 394 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196 +DG I+ Q+ + + L I D L+D GEY+C + G C+ L V+E + Sbjct: 395 RDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVV 454 Query: 1197 --NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 F ++ L + +VTWYK + IED +F + SD K +L+ Sbjct: 455 PPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLV 514 Query: 1255 IRKCTEDDQCEYTC 1268 IR C D Y+C Sbjct: 515 IRDCALSDTGSYSC 528 Score = 142 bits (344), Expect = 9e-32 Identities = 111/406 (27%), Positives = 180/406 (44%), Gaps = 47/406 (11%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD--DDNVATLVIREVFPEDAGT 580 + V+ E +V G P+P + WF + KP ++ + Y D + + LVI +D Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEG---KPIEENRRVYTMRDGSTSVLVIENAELDDEAM 238 Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640 +TC A N G ++E++ P + G P F ++ Sbjct: 239 YTCKAINDLGEVECSSEML---PTDEAG-------------------------PKFLQRL 270 Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 + + V EGS LE + P+P + WL GE + P +++ E +H L I N Sbjct: 271 ELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVH----TLTIMNT 326 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 EG YT +A N+ GE S L ++ G + PPQ I S+ + +G+ A+V G Sbjct: 327 TLDDEGEYTCIAKNKVGEVSCTAELLVEEGMR-PPQFIVKPSSLQIMEGKMAKFEARVSG 385 Query: 761 NPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 P P + W ++ +P+K + + D +TI+ K+ DEG YT A + G S Sbjct: 386 LPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTII-DAKLNDEGEYTCVATSKAGKDSCS 444 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 + V+E PP F+ + I + E + R+T P P +TWY++ I Sbjct: 445 VELLVDEA----VVPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGG 500 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 D + LVI + + D+G Y C A+N AG++S +TI Sbjct: 501 RFEIYSDDDKHSLVIRDC-ALSDTGSYSCKATNEAGQASCYGELTI 545 Score = 133 bits (322), Expect = 4e-29 Identities = 102/368 (27%), Positives = 166/368 (45%), Gaps = 26/368 (7%) Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 E ++L VT P P + W+ + I + + DG LVI N + + D Y Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRDGSTSVLVIENAELD-DEAMYT 240 Query: 906 CVASNSAGKSSHGARVT-IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYH 962 C A N G+ + + D F++ L+ E EG LE + S +W Sbjct: 241 CKAINDLGEVECSSEMLPTDEAGPKFLQRLELK-EVVEGSRTDLEVEVSGKPKPVVEWLK 299 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI-- 1016 + + + + EG+ D G CI K++ + L+V+E + Sbjct: 300 DGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRP 359 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKP-KKNKYDFEKRGHIRKL 1074 P+FI K ++ E +A E ++ +V W RDG IKP ++ + +FEK + L Sbjct: 360 PQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSV--L 417 Query: 1075 YIRNTSVHDEGEYSCILRD----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEI 1128 I + ++DEGEY+C+ +SC+ E+ V E +PPE + ++ N ++ +G A F++ Sbjct: 418 TIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIARFDV 477 Query: 1129 ELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183 +T A V W+KD I+ ++ D K L I DC L D G YSC E G + Sbjct: 478 RITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATNEAGQA 537 Query: 1184 KCTAILTV 1191 C LT+ Sbjct: 538 SCYGELTI 545 Score = 131 bits (317), Expect = 2e-28 Identities = 101/373 (27%), Positives = 170/373 (45%), Gaps = 27/373 (7%) Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804 + ++V L +V G P+P + W KP+ + + T DG T S+ +++ ++ DE +YT Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRDGST-SVLVIENAELDDEAMYT 240 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 KA N G E S+ + PT+E P F+ R + V E L V+ P P + Sbjct: 241 CKAINDLGEVECSSEML---PTDEAG--PKFLQRLELKEVVEGSRTDLEVEVSGKPKPVV 295 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W ++ E++ PS +T +G+ L I N + D G+Y C+A N G+ S A + ++ Sbjct: 296 EWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLD-DEGEYTCIAKNKVGEVSCTAELLVE 354 Query: 925 VEKVTFVKHLQK--SYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGR 980 E + + + K S + EGK E + S +W + + I +I E Sbjct: 355 -EGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKD 413 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI--PEFIRKLQDFEVKEKDVA 1034 D G C+ + S L+V E + PEF+RK+ + E+ E ++A Sbjct: 414 RSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKISNIELTEGEIA 473 Query: 1035 ILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 +V I A +V W +D E+ +++ L IR+ ++ D G YSC + Sbjct: 474 RFDVRITGTPAPEVTWYKD-EVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYSCKATN 532 Query: 1094 E----SCTAEVTV 1102 E SC E+T+ Sbjct: 533 EAGQASCYGELTI 545 Score = 128 bits (308), Expect = 2e-27 Identities = 103/361 (28%), Positives = 160/361 (44%), Gaps = 22/361 (6%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 E + LE + P+P + W +G+ I +EN V D SVL I N + E Sbjct: 182 ENDAVRLEVEVTGEPKPVVLWFCEGKPI--EENRRVYTMRDGS--TSVLVIENAELDDEA 237 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 YT A+N GE + + T E P+ ++ L+ V +G L +V G P+P + Sbjct: 238 MYTCKAINDLGEVECSSEM-LPTDE-AGPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVV 295 Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W K+ KP + +++G H++TI+ + DEG YT A+N G E S T E Sbjct: 296 EWLKDGELVKPSSLMTLETEGQVHTLTIMN-TTLDDEGEYTCIAKNKVG--EVSC--TAE 350 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 EE PP FI + + + E K ARV+ P P + W R+ I P F Sbjct: 351 LLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEF 410 Query: 884 DGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTID--VEKVTFVKHLQKSYET 940 E V+T +D+++ D G+Y CVA++ AGK S + +D V FV+ + + E Sbjct: 411 --EKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPPEFVRKI-SNIEL 467 Query: 941 EEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 EG+ + + + T + + WY ++ I EI + D G Sbjct: 468 TEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEIYSDDDKHSLVIRDCALSDTGSYS 527 Query: 999 C 999 C Sbjct: 528 C 528 Score = 103 bits (248), Expect = 4e-20 Identities = 106/478 (22%), Positives = 191/478 (39%), Gaps = 52/478 (10%) Query: 932 KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXXXXX 987 K + E EG TV L + + + W+ + K +SG+ HR E+ G Sbjct: 6 KSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIK 65 Query: 988 XXXXXDVGVIKC--------IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE 1039 D G C + + V + P+F R L+D + E +V+ Sbjct: 66 EARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQ 125 Query: 1040 IN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 + S V W +G++++P+ + D L + + + G+Y+C+ +E Sbjct: 126 VTGSPEPKVFWYHNGKLVQPRDH-VDIVHDDEHSSLILMHCPLDLSGKYTCVAENE---- 180 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157 ++N V E+E+T + +V WF +G I+ + + D Sbjct: 181 --------------VENDAVR------LEVEVTGEPKPVVLWFCEGKPIEENRRVYTMRD 220 Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCTA-ILTVEEPSINFTLRLP-EFILVPAN 1211 G L I + +LDD Y+C ++G +C++ +L +E F RL + ++ + Sbjct: 221 GSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQRLELKEVVEGSR 280 Query: 1212 TDAYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 TD L VE+ + V W K +++ + TL ++ + TL I T DD+ EYTC+ Sbjct: 281 TD--LEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIA 338 Query: 1271 L----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + T +L VE PP+ + +I G P P EW+ + + Sbjct: 339 KNKVGEVSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARVSGLPGPEVEWLRDGR 398 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 IK + + + + LTI + D G Y + G + + + + PP Sbjct: 399 PIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGKDSCSVELLVDEAVVPP 456 Score = 94.3 bits (224), Expect = 3e-17 Identities = 121/574 (21%), Positives = 227/574 (39%), Gaps = 59/574 (10%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID--GKKQ 1161 +PPE + L++ +VN+GN T I +T V WFKDG + H + + G+ Sbjct: 1 IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60 Query: 1162 KLKIYDCDLDDAGEYSCEVGNS------KCTA-ILTV--EEPSINFTLRLPEFILVPANT 1212 L I + D G+Y C+ NS C +L V +EP F L + + + Sbjct: 61 TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPP-KFERNLKDITIAEGCS 119 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 + V WY +++ + ++ D + +LI+ C D +YTC Sbjct: 120 TRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTC---- 175 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + + E E V L V+ P+P W K I++ + Sbjct: 176 -----------------VAENEVE-----NDAVRLEVEVTGEPKPVVLWFCEGKPIEENR 213 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 D ++ L I+ E D +Y + N+ G + + D+ P LE+ Sbjct: 214 RVYTMRDGSTSVLVIENAELDDEAMYTCKAINDLGEVECSSEMLPTDEAGPKFLQR-LEL 272 Query: 1393 DSSSINICWD-EPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449 D E E +G ++ ++ + + + + ++++ + T +I N + Sbjct: 273 KEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPSSLMTLETEGQVHTLTIMNTTLDDEG 332 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 + A N+V + S T E +++E + KP ++ + + G+P Sbjct: 333 EYTCIAKNKV--GEVSCTAEL--LVEEGMRPPQFIVKP-SSLQIMEGKMAKFEARVSGLP 387 Query: 1510 QPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P+V W RDG+ +K + ++R Y C+A + G+ SC V Sbjct: 388 GPEVEWLRDGRPIKPGRRFQIEFEKDRSVLTIIDAKLNDEGEYTCVATSKAGK--DSCSV 445 Query: 1566 GIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + + + E +++ + G+ I G P PEV WYK+ +E+ + I Sbjct: 446 ELLVDEAV-VPPEFVRKISNIELTEGEIARFDVRITGTPAPEVTWYKDEVPIEDGGRFEI 504 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + + + I++ S + Y+ +A+N AG +S Sbjct: 505 YSDDDKHSLVIRDCALSDTGSYSCKATNEAGQAS 538 Score = 76.2 bits (179), Expect = 9e-12 Identities = 104/473 (21%), Positives = 189/473 (39%), Gaps = 51/473 (10%) Query: 1226 DVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKV 1281 +V W+K + +F + + TL+I++ D +Y C ++ T+ V Sbjct: 33 EVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGEVTSSCNV 92 Query: 1282 EVVEF----PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 +V+ PPK ++ I G V P+P W N K+++ H Sbjct: 93 DVLHVAPKEPPKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIV 152 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 D + +SL + +G Y EN + V + V + +P KP +L Sbjct: 153 HDDEHSSLILMHCPLDLSGKYTCVAENEVENDAVRLEVEVTGEP----KPVVLWF----- 203 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 C +P + E + + T +++ + + I+N + + + A+N Sbjct: 204 --CEGKP-----------IEENRRVYT-----MRDGSTSVLVIENAELDDEAMYTCKAIN 245 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 D+ + ++E + +E LK + D+E+ G P+P V W + Sbjct: 246 --DLGEVECSSEMLPTDEAGPKFLQRLE--LKEVVEGSRTDLEVEV--SGKPKPVVEWLK 299 Query: 1518 DGKKLKTAKA-TYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQ--KP 1571 DG+ +K + T E Y CIA N GEV + + +++ +P Sbjct: 300 DGELVKPSSLMTLETEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVEEGMRP 359 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 I Q + G A + G+P PEV W ++G ++ + + I ++ SV+ Sbjct: 360 PQFIVKPSSLQIME-GKMAKFEARVSGLPGPEVEWLRDGRPIKPGRRFQIEFEKDRSVLT 418 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 I + K + +YT A++ AG S V L V D+ P P +R+IS +T Sbjct: 419 IIDAKLNDEGEYTCVATSKAGKDSCSVELLV-DEAVVP--PEFVRKISNIELT 468 Score = 70.9 bits (166), Expect = 4e-10 Identities = 56/202 (27%), Positives = 82/202 (40%), Gaps = 12/202 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENISVAIESDMH 689 IPP F + V+EG+ + L + P+P++ W G+ + +P V +++ Sbjct: 1 IPPEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVY 60 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQ 748 L I + G Y A N GE + + + KEPP+ LK + + + Sbjct: 61 ----TLVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDVLHVAPKEPPKFERNLKDITIAE 116 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLK 806 G S QV G+P P + W N K V+ D HS IL + G YT Sbjct: 117 GCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEHSSLILMHCPLDLSGKYTCV 176 Query: 807 AENSEGIAETSAVITVEEPTEE 828 AEN E AV E T E Sbjct: 177 AENE---VENDAVRLEVEVTGE 195 Score = 69.7 bits (163), Expect = 8e-10 Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 4/101 (3%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 PT E P F+++L K +GS E +V G P+P + W + ++KPS Sbjct: 258 PTDEA---GPKFLQRLELKEVVEGSRTDLEVEVSGKPKPVVEWLKDGELVKPS-SLMTLE 313 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + V TL I +D G +TC+AKN G S T EL+VE Sbjct: 314 TEGQVHTLTIMNTTLDDEGEYTCIAKNKVGEVSCTAELLVE 354 Score = 68.9 bits (161), Expect = 1e-09 Identities = 41/127 (32%), Positives = 64/127 (50%), Gaps = 5/127 (3%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L DE YT K + D V + +E + P FV K+ +G +F+ ++ Sbjct: 424 LNDEGEYTCVATSKAGK--DSCSV--ELLVDEAVVPPEFVRKISNIELTEGEIARFDVRI 479 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P P++TW++ I+ F++Y DDD +LVIR+ D G+++C A N AG AS Sbjct: 480 TGTPAPEVTWYKDEVPIEDGGRFEIYSDDDK-HSLVIRDCALSDTGSYSCKATNEAGQAS 538 Query: 594 STTELIV 600 EL + Sbjct: 539 CYGELTI 545 Score = 67.3 bits (157), Expect = 4e-09 Identities = 41/128 (32%), Positives = 62/128 (48%), Gaps = 5/128 (3%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L DE YT + K+ E + + EE P F+ K +G +FE +V Sbjct: 328 LDDEGEYTCIAKNKVGE----VSCTAELLVEEGMRPPQFIVKPSSLQIMEGKMAKFEARV 383 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P P++ W R IKP + FQ+ ++ D + L I + D G +TCVA + AG S Sbjct: 384 SGLPGPEVEWLRDGRPIKPGRRFQIEFEKDR-SVLTIIDAKLNDEGEYTCVATSKAGKDS 442 Query: 594 STTELIVE 601 + EL+V+ Sbjct: 443 CSVELLVD 450 Score = 50.8 bits (116), Expect = 4e-04 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 3/93 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK--PSQDFQMYYDDDNVAT 567 P F LR +G+TV V G P+P++ WF+ + P + F++ + V T Sbjct: 3 PEFKSALRDIEVNEGNTVTLRIHVTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGE-VYT 61 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 LVI+E D G + C A N+AG +S+ + V Sbjct: 62 LVIKEARGSDTGKYLCKAYNSAGEVTSSCNVDV 94 Score = 50.4 bits (115), Expect = 5e-04 Identities = 21/78 (26%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F L+ +G + +F+ QV G P P++ W+ +++P + +DD++ ++L+ Sbjct: 103 PKFERNLKDITIAEGCSTRFDVQVTGSPEPKVFWYHNGKLVQPRDHVDIVHDDEH-SSLI 161 Query: 570 IREVFPEDAGTFTCVAKN 587 + + +G +TCVA+N Sbjct: 162 LMHCPLDLSGKYTCVAEN 179 Score = 39.9 bits (89), Expect = 0.75 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 5/78 (6%) Query: 1596 IEGIPPPEVIWYKNGNKLEN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG- 1652 + G P PEV W+K+G + + + + + + IKE + S + KY +A N+AG Sbjct: 26 VTGSPKPEVDWFKDGKPVSGLPHRRFEVGCVGEVYTLVIKEARGSDTGKYLCKAYNSAGE 85 Query: 1653 -TSSVEVTLKVYDKPSKP 1669 TSS V + ++ P +P Sbjct: 86 VTSSCNVDV-LHVAPKEP 102 >UniRef50_Q4S2G3 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=2; Clupeocephala|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2528 Score = 222 bits (543), Expect = 7e-56 Identities = 253/1073 (23%), Positives = 428/1073 (39%), Gaps = 91/1073 (8%) Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 +PP + + + + V EG + L C + A P P+I W G+ + I + M Sbjct: 250 VPPRITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHILPGGQM-- 307 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L++ + G Y A N G+ I+L + P++ + + G Sbjct: 308 ----LQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPSLKPRLDAASDLVTPQVGS 363 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 SVILS + G P P +TW KN + A + D + + I+ + V D+G YT K N Sbjct: 364 SVILSCEAHGVPEPEVTWYKNGLQL-APRNGFEMDRYQLEIVGVQ-VADDGTYTCKVSNV 421 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G + + +TV P P L + ++ + + L + + PVPSITW ++ Sbjct: 422 AGQVDRTFRLTVHVP------PVLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDG 475 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I S + G +EL + G Y CVA NS G++ +T+ V Sbjct: 476 TPIESSLQWQWSIRGNRLELGPLTL---AHGGVYTCVAENSEGQTQKDYALTVQVSPTIL 532 Query: 931 VKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 G+ + LECQ + T W + + G D+R I+ Sbjct: 533 DSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEGSALTLLR 592 Query: 989 XXXXDVGVIKCIV-----KDQETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEI-N 1041 D G C+ + + T+ V V +I ++ V + V LE ++ Sbjct: 593 LSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQDSVVTLECQVAG 652 Query: 1042 SETADVVWERDGE--IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 S + W ++G ++ P+ + L I + D G Y+C+ R ++ AE Sbjct: 653 SPPPQISWLKNGHPLLLSPRTRLLSADS-----VLRISPVQLSDSGVYTCVARSQAGLAE 707 Query: 1100 VTV---VELPPEI--ITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHI 1152 ++ V++PP + + ++ + +G+ T E +G + WFKDG + S H Sbjct: 708 LSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCE-ARGVPPPTLTWFKDGQPL--SLHR 764 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 L +DG++ +L++ D DAG YSC + G+S T LTV EP + PE + + Sbjct: 765 NLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTSSTSPEELTI 824 Query: 1209 PANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 N+ L +P TL TW K +E ++ I + I K +D Sbjct: 825 AVNSPLELECSATGVPPPTL--TWLKDGHPLELSD----IVQEDGHLIRISKVQVEDAGL 878 Query: 1266 YTCVLLD-AKSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 YTC+ A K V+ PP + D + + +TL + P P EW Sbjct: 879 YTCLASSLAGEDGKNHWIRVQVPPTLFGSDEVKTLTVPVNGHLTLECLADSDPAPEIEWY 938 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + ++ + + L I++V D+G+Y + N G + + V IL Sbjct: 939 KDEVKVQLGGRVQQLAGGQY--LEIQEVRPEDSGLYSCVVTNMAGSSSLFFTVEIL---L 993 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 PP +I SS + + G ++ VE T W TQ Sbjct: 994 PP------KIRESSSEVT----THVGQDALLLCEVEEDAQATVTWRK-DGFPITQDHKYT 1042 Query: 1443 LKTNSSYRFRAYAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 L + S R +++ S +++ ++ I +P + N+T Sbjct: 1043 LLSEGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISPGPFNVTVTAGMRA 1102 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXXXYKCIAFND 1555 L+C G+P PKV+W R+GK L ++ + R ++C A ND Sbjct: 1103 VLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFECTAVND 1162 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVG-DEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 GE V +Q P I +D+ V + ++G P P V+W K+G KL Sbjct: 1163 AGEERRVVEVILQVPPTI---EDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAKLS 1219 Query: 1615 N-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + Y + T ++ I + SH+ +YT A N+AG + ++L V + P Sbjct: 1220 SRGGTYRVL---PTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESP 1269 Score = 202 bits (492), Expect = 1e-49 Identities = 237/1068 (22%), Positives = 427/1068 (39%), Gaps = 73/1068 (6%) Query: 632 IPPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 + PT S+ P G ++ LEC+ P P ++WL G + +N + + Sbjct: 527 VSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEG- 585 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S L + + GTYT +AV+ G + L + + P + + V Q Sbjct: 586 ---SALTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVP-REVPVTQD 641 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 V L QV G+P P I+W KN P+ P S+ + P ++ D GVYT A + Sbjct: 642 SVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLSADSVLRISPVQLSDSGVYTCVARS 701 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G+AE S + V+ P + P+ + +T+ + + L P P++TW+++ Sbjct: 702 QAGLAELSYDVQVQVPPGVDHVEPV-----EPVTIVQGSLVTLSCEARGVPPPTLTWFKD 756 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKV 928 + +S + DG+ L + +V + D+G Y CVASN AG S+ +T+ + K+ Sbjct: 757 GQPLSLHRNLL--LDGQETRLQLPDVATS-DAGLYSCVASNQAGSSTKTFNLTVLEPPKM 813 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXX 986 T ++ + LEC + + W K+ ++ +I+QE Sbjct: 814 TSSTSPEE-LTIAVNSPLELECSATGVPPPTLTWL---KDGHPLELSDIVQED-GHLIRI 868 Query: 987 XXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVE 1039 D G+ C+ E ++ +P + EVK V + LE Sbjct: 869 SKVQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTL--FGSDEVKTLTVPVNGHLTLECL 926 Query: 1040 INSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 +S+ A ++ W +D +K + + G + L I+ D G YSC++ + + ++ Sbjct: 927 ADSDPAPEIEWYKDE--VKVQLGGRVQQLAGG-QYLEIQEVRPEDSGLYSCVVTNMAGSS 983 Query: 1099 EV--TV-VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQL 1154 + TV + LPP+I + G A E+ + A V W KDG I + L Sbjct: 984 SLFFTVEILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTL 1043 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP 1209 +G L+++D L DAG Y C V N + + P+I+ P + V Sbjct: 1044 LSEGS---LRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISPG---PFNVTVT 1097 Query: 1210 ANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 A A L+ E V+W + ++ ++ + +L++ +++D+ + C Sbjct: 1098 AGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFEC 1157 Query: 1269 VLLDAKSTTKLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 ++ + VEV+ + PP I D + S V L Q PQP W + Sbjct: 1158 TAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQGRPQPTVVWTKSGAK 1217 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPG 1385 + T + + L I V + AG Y N+ G A +++T+ + P P Sbjct: 1218 LSSRGGTYRVLPT--GLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESPEIGPMA 1275 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 + + + ++ C E + +I + E I T +SV ++ + Sbjct: 1276 EEVQVVLHHGTVLPC--EAQGFPRPSITWQR-EGVSIATGHRLSV--LSNGALKFSRVTL 1330 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 + ++ A NE ++ T +V P + P T+ + + L C+ Sbjct: 1331 GDAGMYQCLAKNEAGVA-VGRTRLVLQV-------PPVLSVPRMEYTSVLGQPVSLECVA 1382 Query: 1506 GGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G P P+V W ++ + ++ A Y C A N G Sbjct: 1383 DGQPPPEVAWLKERRPVIEGAHIRIFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMR 1442 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + IQ P+I+ + D+ G + L+ +G P P + W KNG + N + Sbjct: 1443 LAIQVPPLISPAQTDLSVVQ--GFQALLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLR 1500 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 +I E+ + + +T A+NTAG++ + L + +P+ E P Sbjct: 1501 SGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELP 1548 Score = 194 bits (472), Expect = 3e-47 Identities = 245/1098 (22%), Positives = 434/1098 (39%), Gaps = 99/1098 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS ++L C +PEP++ W G ++ P E D + L+I V+ +GT Sbjct: 362 GSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGF----EMDRYQ----LEIVGVQVADDGT 413 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766 YT N G+ L + PP + L +S+ G V LS Q G P P+I Sbjct: 414 YTCKVSNVAGQVDRTFRLTVHV----PPVLEGSLWESLNYTLGSHVTLSCQASGFPVPSI 469 Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EP 825 TW K+ P+++ + L P + GVYT AENSEG + +TV+ P Sbjct: 470 TWLKDGTPIESSLQWQWSIRGNRLELGPLTLAHGGVYTCVAENSEGQTQKDYALTVQVSP 529 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNF 883 T ++E P E++ + L + T NP P ++W ++ I+ S+ I Sbjct: 530 TILDSEHP------SEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATP 583 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEE 942 +G + L+ + D DSG Y C+A + AG+ + + + V + + + + Sbjct: 584 EGSALTLLRLSPD---DSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPREVPVTQ 640 Query: 943 GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 V LECQ S W N + ++ D GV C+ Sbjct: 641 DSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLSAD--SVLRISPVQLSDSGVYTCV 698 Query: 1001 VKDQETSTMLV--VKETIP---EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE 1054 + Q L V+ +P + + ++ + + + L E + W +DG+ Sbjct: 699 ARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQ 758 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEII 1110 + +N G +L + + + D G YSC+ +++ T +TV+E PP++ Sbjct: 759 PLSLHRNLL---LDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVLE-PPKMT 814 Query: 1111 TRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 + +++ + E+E + + W KDG ++ S+ +Q DG ++I Sbjct: 815 SSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPLELSDIVQE--DG--HLIRISK 870 Query: 1168 CDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI--- 1220 ++DAG Y+C G + V+ P F + + VP N +LT+E Sbjct: 871 VQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLFGSDEVKTLTVPVN--GHLTLECLAD 928 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 D ++ WYK + ++ + ++ + L I++ +D Y+CV+ + ++ L Sbjct: 929 SDPAPEIEWYKDEVKVQLGGRVQQLAG--GQYLEIQEVRPEDSGLYSCVVTNMAGSSSLF 986 Query: 1281 VEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI 1338 V + PPKI + E G D LL + + Q W + I + K+T S Sbjct: 987 FTVEILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWRKDGFPITQDHKYTLLS- 1045 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNI-LEIDSS 1395 SL + V+ +DAG Y + N G H + + V + SP G N+ + Sbjct: 1046 ---EGSLRVHDVQLSDAGRYYCSVSNQAGSDHRGIYLRVFVAPAISP-GPFNVTVTAGMR 1101 Query: 1396 SINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR-FRA 1453 ++ C E TG + + + +D ++ + + + + ++ F Sbjct: 1102 AVLSC----ETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLVLLSPSDEDEGYFEC 1157 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 AVN DA E +VI + PT+E + +T + L C G PQP V Sbjct: 1158 TAVN-----DAGEERRVVEVILQVP---PTIEDDVTAVTAVKMSPVALPCHVQGRPQPTV 1209 Query: 1514 TWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 W + G KL + TY Y C A N G + +Q+ P Sbjct: 1210 VWTKSGAKLSSRGGTYRVLPTGLLEITAVLPSHAGRYTCSARNSAGLAHKHISLTVQESP 1269 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 I E+++ G ++ +G P P + W + G + ++ + ++ Sbjct: 1270 EIGPMAEEVQVVLHHGT--VLPCEAQGFPRPSITWQREGVSIATGHRLSVLS---NGALK 1324 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTL-----KVYDKPSKPEGPVIMREISRESVTIE 1686 + + Y A N AG + L V P V+ + +S E V + Sbjct: 1325 FSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRMEYTSVLGQPVSLECVA-D 1383 Query: 1687 WKPPLDDGGLELTKYAIE 1704 +PP + L+ + IE Sbjct: 1384 GQPPPEVAWLKERRPVIE 1401 Score = 186 bits (452), Expect = 8e-45 Identities = 254/1192 (21%), Positives = 459/1192 (38%), Gaps = 120/1192 (10%) Query: 508 MAPIFVEKLRPKHT--PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 ++P ++ P P G + ECQ G P P ++W + I++ S + + + Sbjct: 527 VSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGSDNRHIVATPEGS 586 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 A ++R + P+D+GT+TC+A + AG + L V P S G E TV Sbjct: 587 ALTLLR-LSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAG-ETTV------------ 632 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 P+ V + S + LEC++ P P I+WL G ++ + + Sbjct: 633 --------------PREVPVTQDSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRL-LS 677 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKS 743 +D SVL+I+ V+ G YT VA ++ G A L ++++ PP V +EP++ Sbjct: 678 AD-----SVLRISPVQLSDSGVYTCVARSQAGLAELSYDVQVQV----PPGVDHVEPVEP 728 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 + + QG V LS + G P PT+TW K+ +P+ + L D G+Y Sbjct: 729 VTIVQGSLVTLSCEARGVPPPTLTWFKDGQPLSLHRNLLLDGQETRLQLPDVATSDAGLY 788 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + A N G + + +TV EP + + +E+T+ ++L T P P+ Sbjct: 789 SCVASNQAGSSTKTFNLTVLEPPKMTSS-----TSPEELTIAVNSPLELECSATGVPPPT 843 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +TW ++ + S+ + + DG I + V+ D+G Y C+AS+ AG+ + + Sbjct: 844 LTWLKDGHPLELSDIVQE--DGHLIRISKVQVE---DAGLYTCLASSLAGEDGKNHWIRV 898 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981 V F K+ + LEC + +WY K E+ + Q Sbjct: 899 QVPPTLFGSDEVKTLTVPVNGHLTLECLADSDPAPEIEWY--KDEVKVQLGGRVQQLAGG 956 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTML--VVKETIPEFIRKLQD---FEVKEKDVAIL 1036 D G+ C+V + S+ L V+ +P IR+ V + + + Sbjct: 957 QYLEIQEVRPEDSGLYSCVVTNMAGSSSLFFTVEILLPPKIRESSSEVTTHVGQDALLLC 1016 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 EVE +++ A V W +DG I + +KY G +R + + + D G Y C + +++ Sbjct: 1017 EVEEDAQ-ATVTWRKDGFPI-TQDHKYTLLSEGSLR---VHDVQLSDAGRYYCSVSNQAG 1071 Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEI---QFS 1149 + + V + P I N V G +A E T V W ++G + Q S Sbjct: 1072 SDHRGIYLRVFVAPAISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLS 1131 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPE 1204 +L G L D +D G + C N + ++ P+I + Sbjct: 1132 GAFRLLSSGSLVLLSPSD---EDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVT 1188 Query: 1205 FI-LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + + P ++ P T V W K + + + + + L I Sbjct: 1189 AVKMSPVALPCHVQGR-PQPT--VVWTKSGAKL--SSRGGTYRVLPTGLLEITAVLPSHA 1243 Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 YTC ++ + + V+ P+I E ++ L + Q FP+P+ W Sbjct: 1244 GRYTCSARNSAGLAHKHISLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITW- 1302 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + + + S+ S A L +V DAG+Y+ +N G V + T L Sbjct: 1303 -QREGVSIATGHRLSVLSNGA-LKFSRVTLGDAGMYQCLAKNEAG---VAVGRTRLVLQV 1357 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 PP +L + +P + + V + Q W+ + I+ Sbjct: 1358 PP----VLSVPRMEYTSVLGQPVS------LECVADGQPPPEVAWLKERRPVIEGAHIR- 1406 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK--IQSPTVEKPLK-NITTEPNEDI 1499 + N + + ++ + + + + + IQ P + P + +++ Sbjct: 1407 IFANGTLAIASTQRSDAGLYTCTAKNLAGRASHDMRLAIQVPPLISPAQTDLSVVQGFQA 1466 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFND 1555 L C G P+P+++W ++G + Y + C+A N Sbjct: 1467 LLPCAAQGSPEPRISWEKNGTPVPNLPGKYTVLRSGELIIERAEVSWADAGVFTCVATNT 1526 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G + I +P D+ G ++ +G PPP + W N N Sbjct: 1527 AGSARQDSRLSINMRPAFKELPGDVTLNK--GQNLALSCHAQGTPPPVISWTVN-----N 1579 Query: 1616 DKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + T E S + I+ + SH+ Y A N+ G+ ++V + P Sbjct: 1580 SPQTGATLDESGRSSLIIENVTTSHAGTYVCIAENSVGSIRALSFVRVREPP 1631 Score = 161 bits (392), Expect = 1e-37 Identities = 188/843 (22%), Positives = 330/843 (39%), Gaps = 69/843 (8%) Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 +L+I G +TCV N AG + ++ P H Sbjct: 10 SLIIENTMLFHEGQYTCVVTNTAGEDKRDFRVTIQVPPVFHRVTNREAAWGLGHEGDDKD 69 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 D++E + G + L C AIP P ++W G++++ + + V + Sbjct: 70 DMVERLDVVL-----------GHPVSLSCESNAIPPPKLSWHKDGQKLMSGDGV-VLLPG 117 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 VL+I V+K G YT AVN GE + L I E ++ M Sbjct: 118 -----AQVLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHILVPPVITGATEEFMEEMAA 172 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 +V+L V G P P ++W K+ +PV+ P + L +V D Y Sbjct: 173 VVNSTVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQLHLLRVQVSDMAGYLCV 232 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 AEN G E +TV+ P P + +E++V E + L+ V P P ITW Sbjct: 233 AENKVGTVEKLFSLTVQVP------PRITGRMEEEVSVTEGRMVSLLCDVQAYPPPEITW 286 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 R+ ++++ I G+ ++L ++ D+G Y C A+NSAG+ +++ V Sbjct: 287 TRDGQVLAFGSGIHILPGGQMLQLPRARLE---DAGQYVCTATNSAGQDQKSILLSVYV- 342 Query: 927 KVTFVKHLQKSYE---TEEGKTVILECQTSHTV---STKWYHNKKEISGMDHREIIQEGR 980 + + L + + + G +VIL C+ +H V WY N +++ + E+ + Sbjct: 343 RPSLKPRLDAASDLVTPQVGSSVILSCE-AHGVPEPEVTWYKNGLQLAPRNGFEMDR--- 398 Query: 981 XXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAIL 1036 D G C V + Q T + P L + L Sbjct: 399 -YQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLNYTLGSHVTL 457 Query: 1037 EVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 + + + W +DG I+ ++ + RG+ +L + ++ G Y+C+ + Sbjct: 458 SCQASGFPVPSITWLKDGTPIE-SSLQWQWSIRGN--RLELGPLTLAHGGVYTCVAENSE 514 Query: 1096 CTAE---VTVVELPPEIITRLQNQKVN--KGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149 + V++ P I+ +V+ G + + E + T + W KDG ++ S Sbjct: 515 GQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGNPTPHLSWLKDGVIVEGS 574 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG-NSKCTAILTVEEPSINFTLRLPE 1204 ++ + + L + DD+G Y+C G +K + + PSI +P Sbjct: 575 DNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSIAGETTVPR 634 Query: 1205 FILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 VP D+ +T+E ++W K + + + L+S L I Sbjct: 635 --EVPVTQDSVVTLECQVAGSPPPQISWLKNGHPLLLSPRTRLLS--ADSVLRISPVQLS 690 Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 D YTCV +L +V V+ PP + V+ I +GS VTL + + P P Sbjct: 691 DSGVYTCVARSQAGLAELSYDVQVQVPPGVDHVEPVEPVTIVQGSLVTLSCEARGVPPPT 750 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 W + + + H +D + L + V +DAG+Y N G + N+T+L Sbjct: 751 LTWFKDGQPLS--LHRNLLLDGQETRLQLPDVATSDAGLYSCVASNQAGSSTKTFNLTVL 808 Query: 1379 DKP 1381 + P Sbjct: 809 EPP 811 Score = 126 bits (303), Expect = 9e-27 Identities = 217/1080 (20%), Positives = 386/1080 (35%), Gaps = 107/1080 (9%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 VE + P GS V C+ G P P +TWF+ + ++ + D L + + Sbjct: 723 VEPVEPVTIVQGSLVTLSCEARGVPPPTLTWFKDGQPLSLHRNLLL---DGQETRLQLPD 779 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 V DAG ++CVA N A S+T+ +TV LE Sbjct: 780 VATSDAGLYSCVASNQ---AGSSTKTF----------NLTV---------------LEPP 811 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 T S P+ + S + LEC +P P + WL G + +S ++ D H+ Sbjct: 812 KMTSSTSPEELTIAVNSPLELECSATGVPPPTLTWLKDGHPL----ELSDIVQEDGHL-- 865 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGE 750 ++I+ V+ G YT +A + GE ++++ PP + + +K++ V Sbjct: 866 --IRISKVQVEDAGLYTCLASSLAGEDGKNHWIRVQV----PPTLFGSDEVKTLTVPVNG 919 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 + L +P P I W K+ V+ + + G I ++P +D G+Y+ Sbjct: 920 HLTLECLADSDPAPEIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVRP---EDSGLYSCVV 976 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G +S TV E PP E+T L+ V + ++TW Sbjct: 977 TNMAG--SSSLFFTV-----EILLPPKIRESSSEVTTHVGQDALLLCEVEEDAQATVTWR 1029 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ I+ T +G L + +V D+G Y C SN AG G + + V Sbjct: 1030 KDGFPITQDHKYTLLSEG---SLRVHDVQLS-DAGRYYCSVSNQAGSDHRGIYLRVFVAP 1085 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXX 985 + + G +L C+T+ K W N K + + Sbjct: 1086 A--ISPGPFNVTVTAGMRAVLSCETTGIPPPKVSWKRNGKPLDVSQLSGAFRLLSSGSLV 1143 Query: 986 XXXXXXXDVGVIKC-IVKD--QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G +C V D +E + V+ + P + + L + Sbjct: 1144 LLSPSDEDEGYFECTAVNDAGEERRVVEVILQVPPTIEDDVTAVTAVKMSPVALPCHVQG 1203 Query: 1043 E-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 VVW + G + + Y G L I G Y+C R+ + A Sbjct: 1204 RPQPTVVWTKSGAKLSSRGGTYRVLPTG---LLEITAVLPSHAGRYTCSARNSAGLAHKH 1260 Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTID 1157 + V+ PEI + +V + E + W ++G I + + + + Sbjct: 1261 ISLTVQESPEIGPMAEEVQVVLHHGTVLPCEAQGFPRPSITWQREGVSIATGHRLSVLSN 1320 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTD 1213 G LK L DAG Y C N A+ L ++ P + R+ E+ V Sbjct: 1321 G---ALKFSRVTLGDAGMYQCLAKNEAGVAVGRTRLVLQVPPVLSVPRM-EYTSVLGQPV 1376 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL--L 1271 + V +V W K++ + + + ++ TL I D YTC L Sbjct: 1377 SLECVADGQPPPEVAWLKERRPVIEGAHIRIFAN---GTLAIASTQRSDAGLYTCTAKNL 1433 Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 +++ +++ ++ PP I + + + +G L Q P+P W N + Sbjct: 1434 AGRASHDMRL-AIQVPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTPVPNL 1492 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + S + +V DAG++ N G A + ++I +P+ P + Sbjct: 1493 PGKYTVLRSGELIIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMRPAFKELPGDVT 1552 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 ++ + T I + V + T + ++ I+N+ T+ + + Sbjct: 1553 LNKGQNLALSCHAQGTPPPVISWTVNNSPQTGAT----LDESGRSSLIIENVTTSHAGTY 1608 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI--TTEPNEDIELTCIFGGVP 1509 A N V + + +++ P V K + T L C G P Sbjct: 1609 VCIAENSVG---------SIRALSFVRVREPPVLKGEARMSQTVVQGSSAILDCPIHGDP 1659 Query: 1510 QPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 P + W RDG L++ + Y+C+A ++ G E + + +Q Sbjct: 1660 SPVLQWLRDGHPLLRSHRIQALLNGSLVIYSINAADEGEYQCLAESEAGTAERTITLKVQ 1719 Score = 103 bits (246), Expect = 7e-20 Identities = 127/559 (22%), Positives = 218/559 (38%), Gaps = 40/559 (7%) Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194 W KDG ++ + + L + G Q L+I +DAG Y+C E G L + P Sbjct: 99 WHKDGQKLMSGDGVVL-LPGA-QVLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHILVP 156 Query: 1195 SI--NFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 + T E + N+ L ++ + T V+W K ++ + + D + Sbjct: 157 PVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQL 216 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKIVD-YEREYRIKRGSDVTLLV 1309 L+ + D Y CV + T KL V+ PP+I E E + G V+LL Sbjct: 217 HLL--RVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPPRITGRMEEEVSVTEGRMVSLLC 274 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCK--HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 D QA+P P W + +++ H P L + + DAG Y N+ G Sbjct: 275 DVQAYPPPEITWTRDGQVLAFGSGIHILPG----GQMLQLPRARLEDAGQYVCTATNSAG 330 Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 + +++ +PS KP + D++S + P+ G+S I+ E + E Sbjct: 331 QDQKSILLSVYVRPSL--KPRL---DAASDLVT---PQ-VGSSVILS--CEAHGVPEPEV 379 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-----ASETTEYYKVIKETKIQSP 1482 KN Q + +N Y+ V D ++ + + + T P Sbjct: 380 TWYKN--GLQLAPRNGFEMDRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPP 437 Query: 1483 TVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXX- 1539 +E L +++ + L+C G P P +TW +DG ++++ + + R Sbjct: 438 VLEGSLWESLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNRLELGP 497 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y C+A N G+ + + +Q P I S + +G+E + G Sbjct: 498 LTLAHGGVYTCVAENSEGQTQKDYALTVQVSPTILDSEHPSEVSAPMGEELSLECQATGN 557 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P + W K+G +E +I + S + + L S YT A + AG + T Sbjct: 558 PTPHLSWLKDGVIVEGSDNRHIVATPEGSALTLLRLSPDDSGTYTCLAVSPAGRQTKIYT 617 Query: 1660 LKVYDKPSKPEGPVIMREI 1678 L V PS + RE+ Sbjct: 618 LFVLVPPSIAGETTVPREV 636 Score = 82.2 bits (194), Expect = 1e-13 Identities = 75/294 (25%), Positives = 115/294 (39%), Gaps = 20/294 (6%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP S V +G LL C PEP I+W G VP+ + + Sbjct: 1447 VPPLISPAQTDLSVVQGFQALLPCAAQGSPEPRISWEKNGTP-VPNLPGKYTVLRSGEL- 1504 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +++ V G +T VA N G A L I P E + + +G++ Sbjct: 1505 --IIERAEVSWADAGVFTCVATNTAGSARQDSRLSINMR----PAFKELPGDVTLNKGQN 1558 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + LS G P P I+W NN P G S I++ G Y AENS Sbjct: 1559 LALSCHAQGTPPPVISWTVNNSPQTGATLDESG--RSSLIIENVTTSHAGTYVCIAENSV 1616 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G + + V EP E R + V+ I L + +P P + W R+ Sbjct: 1617 GSIRALSFVRVREPPVLKGEA-----RMSQTVVQGSSAI-LDCPIHGDPSPVLQWLRDGH 1670 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 + S I +G LVI ++++ D G+Y+C+A + AG + + + V Sbjct: 1671 PLLRSHRIQALLNGS---LVIYSINAA-DEGEYQCLAESEAGTAERTITLKVQV 1720 Score = 70.9 bits (166), Expect = 4e-10 Identities = 83/448 (18%), Positives = 168/448 (37%), Gaps = 21/448 (4%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VE 1285 ++W+K + + L+ + L I + ++D YTC ++ + E+ + Sbjct: 97 LSWHKDGQKLMSGDGVVLLPGAQ--VLQIARVQKEDAGRYTCQAVNEAGEDHMHFELHIL 154 Query: 1286 FPPKIVDYEREYRIKRG----SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 PP I E+ + S V L D P P W+ + + ++ + I Sbjct: 155 VPPVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQT--DPQHQISKD 212 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG--KPNILEIDSSSINI 1399 L + +V+ +D Y EN G + ++T+ P G + + + +++ Sbjct: 213 GTQLHLLRVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPPRITGRMEEEVSVTEGRMVSL 272 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 D I + + Q + I + + + + + ++ A N Sbjct: 273 LCDVQAYPPPE--ITWTRDGQVLAFGSGIHILPGGQ-MLQLPRARLEDAGQYVCTATNSA 329 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 S Y V K P ++ +T + + L+C GVP+P+VTWY++G Sbjct: 330 GQDQKSILLSVY-VRPSLK---PRLDAASDLVTPQVGSSVILSCEAHGVPEPEVTWYKNG 385 Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 +L +R Y C N G+V+ + + + PV+ S + Sbjct: 386 LQLAPRNGFEMDRYQLEIVGVQVADDGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWE 445 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 + +G ++ G P P + W K+G +E+ ++ + + + + L +H Sbjct: 446 -SLNYTLGSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNR--LELGPLTLAH 502 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 YT A N+ G + + L V P+ Sbjct: 503 GGVYTCVAENSEGQTQKDYALTVQVSPT 530 Score = 61.3 bits (142), Expect = 3e-07 Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 6/172 (3%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + L+C +P PK++W++DG+KL + Y C A N+ Sbjct: 83 VSLSCESNAIPPPKLSWHKDGQKLMSGDGVVLLPGAQVLQIARVQKEDAGRYTCQAVNEA 142 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 GE + I PVIT + E+ ++ V ++ + G P P V W K+G ++ Sbjct: 143 GEDHMHFELHILVPPVITGATEEFMEEMAAVVNSTVVLHCDVTGQPTPAVSWMKDGQPVQ 202 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 D ++ I +K+ T + + ++ S + Y A N GT +L V P Sbjct: 203 TDPQHQI-SKDGTQ-LHLLRVQVSDMAGYLCVAENKVGTVEKLFSLTVQVPP 252 Score = 57.2 bits (132), Expect = 5e-06 Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 4/173 (2%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 ++T +++ L+C G P P ++W + A R Y Sbjct: 1550 DVTLNKGQNLALSCHAQGTPPPVISWTVNNSPQTGATLDESGRSSLIIENVTTSHAGTYV 1609 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 CIA N G + V +++ PV+ + Q G ++ I G P P + W ++ Sbjct: 1610 CIAENSVGSIRALSFVRVREPPVLK-GEARMSQTVVQGSSAILDCPIHGDPSPVLQWLRD 1668 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 G+ L + + I S++ I + + +Y A + AGT+ +TLKV Sbjct: 1669 GHPLL--RSHRIQALLNGSLV-IYSINAADEGEYQCLAESEAGTAERTITLKV 1718 Score = 51.2 bits (117), Expect = 3e-04 Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 6/90 (6%) Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 TP GS+V C+ G P P++TW++ + P F+M + L I V D G Sbjct: 358 TPQVGSSVILSCEAHGVPEPEVTWYKNGLQLAPRNGFEM-----DRYQLEIVGVQVADDG 412 Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 T+TC N AG T L V P GS Sbjct: 413 TYTCKVSNVAGQVDRTFRLTVHVPPVLEGS 442 Score = 43.6 bits (98), Expect = 0.061 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 7/93 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V CQ G+P P ITW + I+ S +Q + L + + G +TC Sbjct: 452 GSHVTLSCQASGFPVPSITWLKDGTPIESSLQWQWSIRGNR---LELGPLTLAHGGVYTC 508 Query: 584 VAKNAAGFASSTTELIVE-APL---SDHGSEMT 612 VA+N+ G L V+ +P S+H SE++ Sbjct: 509 VAENSEGQTQKDYALTVQVSPTILDSEHPSEVS 541 Score = 42.3 bits (95), Expect = 0.14 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +M P F E G + C +G P P I+W + S D+ + Sbjct: 1539 NMRPAFKELPGDVTLNKGQNLALSCHAQGTPPPVISW-----TVNNSPQTGATLDESGRS 1593 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +L+I V AGT+ C+A+N+ G + + + V P Sbjct: 1594 SLIIENVTTSHAGTYVCIAENSVGSIRALSFVRVREP 1630 Score = 39.9 bits (89), Expect = 0.75 Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 3/79 (3%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 STV C V G P P ++W + ++ Q+ D + L V D + CV Sbjct: 176 STVVLHCDVTGQPTPAVSWMKDGQPVQTDPQHQISKDGTQLHLL---RVQVSDMAGYLCV 232 Query: 585 AKNAAGFASSTTELIVEAP 603 A+N G L V+ P Sbjct: 233 AENKVGTVEKLFSLTVQVP 251 Score = 39.9 bits (89), Expect = 0.75 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G V C V+ YP P+ITW R ++ + L + EDAG + Sbjct: 266 EGRMVSLLCDVQAYPPPEITWTRDGQVLAFGSGIHIL---PGGQMLQLPRARLEDAGQYV 322 Query: 583 CVAKNAAG 590 C A N+AG Sbjct: 323 CTATNSAG 330 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 5/93 (5%) Query: 510 PIFVEKLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P+ + R T GS+ +C + G P P + W R + S Q + +L Sbjct: 1631 PVLKGEARMSQTVVQGSSAILDCPIHGDPSPVLQWLRDGHPLLRSHRIQALLN----GSL 1686 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 VI + D G + C+A++ AG A T L V+ Sbjct: 1687 VIYSINAADEGEYQCLAESEAGTAERTITLKVQ 1719 >UniRef50_UPI0000DB7011 Cluster: PREDICTED: similar to CG33519-PB isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33519-PB isoform 1 - Apis mellifera Length = 2794 Score = 219 bits (534), Expect = 9e-55 Identities = 234/945 (24%), Positives = 394/945 (41%), Gaps = 90/945 (9%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 L ++ K + E+ ++EE + I L K + T+ FE + PR WF+ Sbjct: 374 LEKESSKADILERESTEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDG 433 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 ++ + ++ + + + ++ ED G +TC N Sbjct: 434 KPLRSGERVRIESSGERFR-MELSKIIIEDEGVYTCSFSNKL------------------ 474 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW 667 G +MT D L P F + + V G + + A P PDI W Sbjct: 475 GEDMT-----EGYLTVQTVDELRR--PKFIETLQDVDVANGKSGMFKAMFTADPVPDITW 527 Query: 668 LFKGEEI-VPDENISVAIE----SDMHMYCSV-LKITNVKKFQEGTYTVVAVNREGEASL 721 FKG+EI D + + ++ SD +V L + K G YT+ N+ GEA Sbjct: 528 YFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAES 587 Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---L 778 L + + I+ L + GES+ A + GNP+P ITW K+ K ++ Sbjct: 588 NAFLNLLLCPE-----IQELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERY 642 Query: 779 PTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF-- 835 + D + T ++K ++ D+G Y + A+N G A A++T +E P+F Sbjct: 643 DFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGEASAQAILT------PYSETPIFSE 696 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVIT 893 I + + K++ ++ R + P P++ W R NE I + I DG N+E V + Sbjct: 697 ILPKKPVECKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNNVESVCS 756 Query: 894 -NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 D G C ASN G + + + + +FV L KS E +EG + L+ + Sbjct: 757 ITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLLPKSTEVDEGGCLELKAKI 816 Query: 953 --SHTVSTKWYHNKKEISGMDHR--EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ET 1006 S WY + ++I +H EI+ +G D G K ++ + E Sbjct: 817 DGSPMPEISWYKDGEKIVPDEHTRIEILPDG-TTKLIIDCVQPLDCGAYKLVINNSTGEQ 875 Query: 1007 STMLVV----KETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN 1061 S++ V + P F + L+D ++ + LE ++ + +V W ++G ++ K Sbjct: 876 SSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKE 935 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELP--PEIITRLQN 1115 Y + I L I + D G YS L + + TA+V + E PE + LQ Sbjct: 936 MYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQP 995 Query: 1116 QKVNKGNKATFEIE-LTKGDALVRWFKDGSEI-QFSNHIQ-LTIDGKKQKLKIYDCDLDD 1172 V +G A E++ L K ++WFK+G EI ++ +++ Q L I +D Sbjct: 996 LSVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPED 1055 Query: 1173 AGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFI------LVPANTDAYLTVEIP 1221 AGEY GN++ T+ I V + + + + P F+ V L+V Sbjct: 1056 AGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFV 1115 Query: 1222 DETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL---LDAKST- 1276 + DV W K + ++ +++FT+ D KK L I C D Y C + L ST Sbjct: 1116 GNPIPDVNWSKDGAPLQPSDRFTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTR 1175 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTK 1335 + V + PP + ++ + D L P+P+ W VN K I++ K Sbjct: 1176 STANVRKIFQPPSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYK 1235 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 D + L +K D+G+YK R N G A+ N+TI+D+ Sbjct: 1236 IKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAANLTIVDE 1280 Score = 203 bits (496), Expect = 4e-50 Identities = 228/904 (25%), Positives = 363/904 (40%), Gaps = 93/904 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + + + P+PDI W G+ + E E D L I V+ +G Sbjct: 610 GESLAWQAIIKGNPKPDITWSKDGKVLEKGERYD--FEEDKRNNKFTLVIKEVEIDDKGA 667 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGNPRPT 765 Y V A N GEAS +L T E P E P K + + V + G PRP Sbjct: 668 YQVTAKNYLGEASAQAIL---TPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPN 724 Query: 766 ITWCKNNKPVKA-----LPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 + W + N+ ++ + + DG+ S+ + D G T +A N G A+TS Sbjct: 725 LKWLRCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCD 784 Query: 820 ITVEEPTEENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V+ T P F+N + T V E G ++L A++ +P+P I+WY++ E I P E Sbjct: 785 LLVQLIT------PSFVNLLPKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEH 838 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE--KVTFVKHLQK 936 + +I + +D G YK V +NS G+ S V I E K +F K L+ Sbjct: 839 TRIEILPDGTTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLE- 897 Query: 937 SYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEG-RXXXXXXXXXXXXD 993 + G+ + LE Q +W+ N + I E D Sbjct: 898 DVKIVVGEPLKLEAQVVAFPNPEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPED 957 Query: 994 VGVIKCIVKD---QETSTMLV---VKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETAD 1046 G V + + T T V KE PEF+ LQ V E A +EV++ T Sbjct: 958 AGTYSMTVSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPR 1017 Query: 1047 VVWERDGEIIKPK-KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVT 1101 + W ++GE I P K + L I + D GEY I + SC ++ Sbjct: 1018 LQWFKNGEEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTIS 1077 Query: 1102 VV--------ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151 VV E P + +++ V +G + G+ + V W KDG+ +Q S+ Sbjct: 1078 VVGKLQSDVSEQKPGFVNPMRDVYVEEGQPLNLSVSFV-GNPIPDVNWSKDGAPLQPSDR 1136 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTA-ILTVEEPSINFTLRLPE 1204 +T DGKK +L+I C+ DAG Y C + N ++ TA + + +P +F + Sbjct: 1137 FTITCDGKKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIFQPP-SFIHAFKD 1195 Query: 1205 FILVPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 +P +L D+TWY +K +++D +K+ + D L ++ CT DD Sbjct: 1196 LQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDS 1255 Query: 1264 CEYTC--VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA-------- 1313 Y C V ++ + +V+ KI +E +KR D + A Sbjct: 1256 GVYKCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTG 1315 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH----A 1369 P+P+ EW N + + + + LTI V+ DAG Y L++ N G A Sbjct: 1316 IPEPDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTA 1375 Query: 1370 DVEMNV-------------TILDK------PSP-PGKPNILEIDSSSINICWDEPENTGN 1409 D+ DK P P +P I + + + W G+ Sbjct: 1376 DLIYETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRHLTLSWKPSIPIGS 1435 Query: 1410 STIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 + Y +E E+ +W + + I I+NL+ Y+FR N+ ISD S Sbjct: 1436 RIPVTYQIEMCELPDGDWFTARTGIRSCVCDIRNLEPFRDYKFRIRVENKYGISDPSPYA 1495 Query: 1469 EYYK 1472 + Y+ Sbjct: 1496 QTYR 1499 Score = 182 bits (442), Expect = 1e-43 Identities = 224/956 (23%), Positives = 389/956 (40%), Gaps = 79/956 (8%) Query: 630 EGIPPTFSKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 E PP K A + V E I+ E ++P D W G+ + E V IES Sbjct: 391 ESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGER--VRIESSG 448 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-GEKEPPQVIEPLKSMIVR 747 + ++++ + EG YT N+ GE L ++T E P+ IE L+ + V Sbjct: 449 ERFR--MELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVA 506 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----------SDGDTHS-ITILKPKK 796 G+S + A +P P ITW + + ++ SD T + +T+ PK Sbjct: 507 NGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKC 566 Query: 797 VKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 KD+ G YTLK +N G AE++A + + E I ++T ++ A Sbjct: 567 SKDDTGEYTLKLKNKYGEAESNAFLNLLLCPE--------IQELNDVTTNVGESLAWQAI 618 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS-GDYKCVASNSAGK 914 + NP P ITW ++ +++ E D N + + + EID G Y+ A N G+ Sbjct: 619 IKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGE 678 Query: 915 SSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILE--CQTSHTVSTKWYHNKKEISGMD 971 +S A +T E F + L +K E ++ V + C + KW +EI D Sbjct: 679 ASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLKWLRCNEEIREDD 738 Query: 972 HREII--QEGRXXXXXXXXXXX--XDVGVIKC----IVKDQETSTMLVVKETIPEFIRKL 1023 +I+ ++G DVG I C I +TS L+V+ P F+ L Sbjct: 739 RYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLL 798 Query: 1024 -QDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081 + EV E L+ +I+ S ++ W +DGE I P ++ KL I Sbjct: 799 PKSTEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQP 858 Query: 1082 HDEGEYSCILRDES------CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GD 1134 D G Y ++ + + C + P L++ K+ G E ++ + Sbjct: 859 LDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPLKLEAQVVAFPN 918 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGNS--KCTAILTV 1191 V+WFK+G ++ + + + L+I C +DAG YS V NS + T V Sbjct: 919 PEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKV 978 Query: 1192 EEPSINFTLRLPEFIL------VPANTDAYLTVEIPDE-TLDVTWYKK-KSVIEDTEKFT 1243 E I R PEF++ V A + V++ + T + W+K + ++ D ++ Sbjct: 979 E---IEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKNGEEIVPDGKRVK 1035 Query: 1244 LISDVK-KRTLIIRKCTEDDQCEYTCVLLDAKSTT----------KLKVEVVEFPPKIVD 1292 +S + LII K T +D EY + + + T+ KL+ +V E P V+ Sbjct: 1036 AVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDVSEQKPGFVN 1095 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 R+ ++ G + L V + P P+ W + ++ + D K L I E Sbjct: 1096 PMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGAPLQPSDRFTITCDGKKTELEINPCEG 1155 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPP----GKPNILEIDSSSINICWDEPENTG 1408 DAG+Y+ R+ N G + PP ++ ++ + Sbjct: 1156 KDAGVYECRISNPLGEDSTRSTANVRKIFQPPSFIHAFKDLQQLPTFDAKFL-ARVSGVP 1214 Query: 1409 NSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISD-ASE 1466 I +YV E + + +K + +++ + S ++ AVN+ ++ A+ Sbjct: 1215 RPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVYKCRAVNKGGEAECAAN 1274 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 T ++ K K + P+ K + + + T G+P+P W+ +G K+ Sbjct: 1275 LTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDKM 1330 Score = 143 bits (346), Expect = 5e-32 Identities = 240/1134 (21%), Positives = 442/1134 (38%), Gaps = 116/1134 (10%) Query: 716 EGEASLPIVLKIK-TGEKEPPQVIEP-LKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 E E+S +L+ + T E PP +I+ L V + ++++ + PR W K+ K Sbjct: 375 EKESSKADILERESTEESAPPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGK 434 Query: 774 PVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 P+++ + +S G+ + + K ++DEGVYT N G T +TV+ T + Sbjct: 435 PLRSGERVRIESSGERFRMELSKII-IEDEGVYTCSFSNKLGEDMTEGYLTVQ--TVDEL 491 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEIISPSETITQNFDGE--N 887 P FI Q++ V + A T +PVP ITWY + +EI S + D + + Sbjct: 492 RRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGS 551 Query: 888 IELVITNVD------SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 +L T V S+ D+G+Y N G++ A + + + ++ L T Sbjct: 552 DKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFLNLLL--CPEIQELN-DVTTN 608 Query: 942 EGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX--DVGVI 997 G+++ + + + W + K + + + ++ R D G Sbjct: 609 VGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAY 668 Query: 998 KCIVKDQ--ETSTMLVVK--ETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWE 1050 + K+ E S ++ P F L V+ KD + +E ++ ++ W Sbjct: 669 QVTAKNYLGEASAQAILTPYSETPIFSEILPKKPVECKDRSDVEFKVRCSGIPRPNLKWL 728 Query: 1051 R-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSV--HDEGEYSC----ILRDESCTAEVTVV 1103 R + EI + + K ++ G+ + T+ D G+ +C I + ++ V Sbjct: 729 RCNEEIREDDRYKIVIQEDGNNVESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQ 788 Query: 1104 ELPPEIITRL-QNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK 1160 + P + L ++ +V++G + ++ G + + W+KDG +I H ++ I Sbjct: 789 LITPSFVNLLPKSTEVDEGGCLELKAKID-GSPMPEISWYKDGEKIVPDEHTRIEILPDG 847 Query: 1161 QKLKIYDCDLD-DAGEYSCEVGNSK------CTAILTVEEPSINFTLRLPEFILV---PA 1210 I DC D G Y + NS C + E +F+ L + +V P Sbjct: 848 TTKLIIDCVQPLDCGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIVVGEPL 907 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTCV 1269 +A + V P+ +V W+K + T++ I++ + L I C +D Y+ Sbjct: 908 KLEAQV-VAFPNP--EVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMT 964 Query: 1270 ----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 L + T K+++E E P+ V + + G + V P P +W N Sbjct: 965 VSNSLGETTGTAKVEIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKPTPRLQWFKNG 1024 Query: 1326 K-IIKKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + I+ K K S+ S +L I+K DAG Y++ N G + + ++++ K Sbjct: 1025 EEIVPDGKRVKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQS 1084 Query: 1384 P---GKPNILEIDSSSINICWDEPENTGNSTI------IYYVVEYQEIDTTEWISVK-NI 1433 KP + + + +P N S + + + + + ++ ++ + Sbjct: 1085 DVSEQKPGFVN-PMRDVYVEEGQPLNLSVSFVGNPIPDVNWSKDGAPLQPSDRFTITCDG 1143 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 KT+ I + + + N + T K+ Q P+ K++ Sbjct: 1144 KKTELEINPCEGKDAGVYECRISNPLGEDSTRSTANVRKIF-----QPPSFIHAFKDLQQ 1198 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX-----XXXXXXXXXXY 1548 P D + GVP+P +TWY + K + Y+ + Y Sbjct: 1199 LPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGDACCLYVKDCTYDDSGVY 1258 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV-------TAVIEGIPP 1601 KC A N GE E + + I + E ++GD + TA + GIP Sbjct: 1259 KCRAVNKGGEAECAANLTIVDEIGKIQKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPE 1318 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS-----V 1656 P+ W+ NG+K+ + + + I + + KYT++ SN G S + Sbjct: 1319 PDFEWFHNGDKMWQTDRIRMDQEGSLLRLTINNVDELDAGKYTLKISNPHGEDSCTADLI 1378 Query: 1657 EVTLKV------------YDKPSK-------PEGPVIMREISRESVTIEWKPPLDDGGLE 1697 TL+ +DK K + P+I R + R +T+ WKP + G Sbjct: 1379 YETLEPRAKKSLGDQYADFDKYRKSGIPLPLADRPIISRMMDRH-LTLSWKPSIPIGSRI 1437 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 Y IE E + W R I+ L +Y FR+ +N G S+ Sbjct: 1438 PVTYQIEMCELPDGDWFTARTGIRSC-VCDIRNLEPFRDYKFRIRVENKYGISD 1490 Score = 90.2 bits (214), Expect = 5e-16 Identities = 79/320 (24%), Positives = 145/320 (45%), Gaps = 20/320 (6%) Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK----KRT 1252 +F +RL E++ V N + I +E D W + +I + +FT I D + +R Sbjct: 2131 DFPVRLREYMKVACNRSPGFSRTITEENFD--W--RTPIIRERRRFTDIMDEEIDDERRA 2186 Query: 1253 LIIRKCTEDD----QCEYTC-VLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV 1305 I R + D+ + ++ LD A++ L+ + P + + I+ G Sbjct: 2187 RINRYGSPDNFTLRRLKHELGTRLDSYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPA 2246 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLEN 1364 L P+P +W N ++++ K + D S L+ + D G YK+ N Sbjct: 2247 QLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARN 2306 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + G V + PS P P ++++ + I + W +P++ GNS ++ Y ++Y+E D+ Sbjct: 2307 SLGQTVVRTRIVEAFVPSGPDSPELVDVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDS 2366 Query: 1425 TEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKIQS 1481 +WI + NI I+NLK +++Y FR A N + S+ ++ K K+Q Sbjct: 2367 IDWIDIASNIDHEFYLIRNLKADTTYNFRLAARNRIGWSEKGIPSKLIKTRLPGCPKVQI 2426 Query: 1482 PTVEKPLKNITTEPNEDIEL 1501 K L+ + TE ++I L Sbjct: 2427 TQAMKHLQEL-TESGQEIVL 2445 Score = 81.0 bits (191), Expect = 3e-13 Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 3/155 (1%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P P + WYKN ++ IT ++ S++ K Y + A N+ G + V Sbjct: 2254 GSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTVV 2313 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 + PS P+ P ++ ++S + + WK P DG + Y ++ E D+ WI + Sbjct: 2314 RTRIVEAFVPSGPDSPELV-DVSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSIDWIDI 2372 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 A + D E Y I+ L + Y FR+ A+N +G+SE Sbjct: 2373 AS-NIDHEFYLIRNLKADTTYNFRLAARNRIGWSE 2406 Score = 77.0 bits (181), Expect = 5e-12 Identities = 77/293 (26%), Positives = 126/293 (43%), Gaps = 25/293 (8%) Query: 1492 TTEPNED--IELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXXXXXXXXXX 1544 +TE +E +EL G P P+++WY+DG+K+ + T + Sbjct: 801 STEVDEGGCLELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPLD 860 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQ---QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 YK + N GE + C V I+ +KP + S ED+K VG+ + A + P Sbjct: 861 CGAYKLVINNSTGEQSSLCAVAIKPERRKPSFSKSLEDVKIV--VGEPLKLEAQVVAFPN 918 Query: 1602 PEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 PEV W+KNG L KE Y I +RI + + Y++ SN+ G ++ + Sbjct: 919 PEVQWFKNGIPLRQTKEMYFINEPIGIIGLRIDSCRPEDAGTYSMTVSNSLGETTGTAKV 978 Query: 1661 KVYDKPSKPEGPVIMREIS-------RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 ++ +K +PE V ++ +S + V + KP L+ K E+ PD R Sbjct: 979 EIEEKERRPEFVVNLQPLSVMEGFPAKMEVKVLGKP---TPRLQWFKNG-EEIVPDGKR- 1033 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 +K + + I+K ++VIA N G S + +V K DV Sbjct: 1034 VKAVSMADGSQALIIEKATPEDAGEYQVIAGNTEGTSSCKGTISVVGKLQSDV 1086 Score = 64.1 bits (149), Expect = 4e-08 Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 10/174 (5%) Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKC 1550 N + L G P+PK+T+Y + + +++ T + Y+ Sbjct: 1560 NHNCNLFWFVYGYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEA 1619 Query: 1551 IAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 +A N+HGE + I + P I E I ++G +TA + G+P PE+ WYK+ Sbjct: 1620 VASNEHGEARQRVCLRIAEYPTFIHRPEETIVMIRRIGQ---LTARVTGVPYPEIKWYKD 1676 Query: 1610 GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 L I KE TS++ I + Y++ A N AG+ S V L V Sbjct: 1677 WKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGSISCSVMLHV 1730 Score = 62.9 bits (146), Expect = 9e-08 Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%) Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814 V G P+P +T+ N++P+++ T + T+ + + +DEG+Y A N G A Sbjct: 1569 VYGYPKPKMTYYFNDQPIESGGRYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEA 1628 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 + + AE P FI+R +E V + +L ARVT P P I WY++ + ++ Sbjct: 1629 RQRVCLRI-------AEYPTFIHRPEETIVMIRRIGQLTARVTGVPYPEIKWYKDWKPLT 1681 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 S I F + L+I + D G Y A N AG S Sbjct: 1682 TSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARNVAGSIS 1723 Score = 60.1 bits (139), Expect = 7e-07 Identities = 47/140 (33%), Positives = 65/140 (46%), Gaps = 9/140 (6%) Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L I + + EG Y VA N GEA + L+I E P I + IV Sbjct: 1602 ATLFINRMLERDEGLYEAVASNEHGEARQRVCLRIA----EYPTFIHRPEETIVMIRRIG 1657 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAE 808 L+A+V G P P I W K+ KP+ + DT S+ I+ VKDEG+Y++ A Sbjct: 1658 QLTARVTGVPYPEIKWYKDWKPLTTSSRIRIEFKEPDT-SLLIISDTMVKDEGLYSVSAR 1716 Query: 809 NSEGIAETSAVITVEEPTEE 828 N G S ++ VEE E Sbjct: 1717 NVAGSISCSVMLHVEENEHE 1736 Score = 59.7 bits (138), Expect = 9e-07 Identities = 37/121 (30%), Positives = 66/121 (54%), Gaps = 7/121 (5%) Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 KE D +++ A N++G ++ ++ V A VPS P +P E+ V ++ W P Sbjct: 2293 KEHDVGSYKVVARNSLGQTV-VRTRIVE----AFVPSGPDSP-ELVDVSDTEILVRWKQP 2346 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 + DG +P+L YN+ ++ W+++ +++ + IR+L + TY R+ ARN IG S Sbjct: 2347 KHDGNSPVLCYNLQYKEGDSIDWIDIAS-NIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405 Query: 2051 E 2051 E Sbjct: 2406 E 2406 Score = 56.4 bits (130), Expect = 8e-06 Identities = 101/492 (20%), Positives = 188/492 (38%), Gaps = 32/492 (6%) Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 PP I+ + + + V+ + P+ + +W + K ++ + + + + Sbjct: 394 PPHIIKSTLADKTVYETQTIVFEVEATSLPRADAKWFKDGKPLRSGERVRIESSGERFRM 453 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTI--LDKPSPPGKPNILE-IDSSSINICWD 1402 + K+ D G+Y N G E +T+ +D+ P L+ +D ++ Sbjct: 454 ELSKIIIEDEGVYTCSFSNKLGEDMTEGYLTVQTVDELRRPKFIETLQDVDVANGKSGMF 513 Query: 1403 EPENTGNST--IIYYVV--EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 + T + I +Y E D+ I+V N + + T S + E Sbjct: 514 KAMFTADPVPDITWYFKGDEIHSEDSRLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGE 573 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + ++ E + P +++ L ++TT E + I G P+P +TW +D Sbjct: 574 YTLKLKNKYGEAESNAFLNLLLCPEIQE-LNDVTTNVGESLAWQAIIKGNPKPDITWSKD 632 Query: 1519 GKKL-KTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV-GIQQKP 1571 GK L K + +E N+ Y+ A N GE ++ + P Sbjct: 633 GKVLEKGERYDFEEDKRNNKFTLVIKEVEIDDKGAYQVTAKNYLGEASAQAILTPYSETP 692 Query: 1572 VIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK--- 1626 + + + + ++ K + E+ V GIP P + W + ++ D Y I +E Sbjct: 693 IFSEILPKKPVECKDRSDVEFKVRC--SGIPRPNLKWLRCNEEIREDDRYKIVIQEDGNN 750 Query: 1627 -TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVT 1684 SV I S K T ASN G++ L V PS E+ E Sbjct: 751 VESVCSITTFCPSDVGKITCRASNIYGSAQTSCDLLVQLITPSFVNLLPKSTEVD-EGGC 809 Query: 1685 IEWKPPLDDGGL-ELTKYAI-EKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRV 1741 +E K +D + E++ Y EK PD + I++ D + C+Q L +C +++ Sbjct: 810 LELKAKIDGSPMPEISWYKDGEKIVPDEHTRIEILPDGTTKLIIDCVQPL--DCG-AYKL 866 Query: 1742 IAQNPVGFSEAL 1753 + N G +L Sbjct: 867 VINNSTGEQSSL 878 Score = 56.4 bits (130), Expect = 8e-06 Identities = 53/223 (23%), Positives = 88/223 (39%), Gaps = 27/223 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATL 568 P F+ + +F +V G PRP ITW+ + I++ +++ D D L Sbjct: 1187 PSFIHAFKDLQQLPTFDAKFLARVSGVPRPDITWYVNEKPIVQDDDKYKIKRDGD-ACCL 1245 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 +++ +D+G + C A N G A L + + + G I Sbjct: 1246 YVKDCTYDDSGVYKCRAVNKGGEAECAANLTI---VDEIGK------------------I 1284 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + PP+F K+ + +G + IPEPD W G+++ + I + E + Sbjct: 1285 QKFEPPSFLKRIGDCEMYKGMPAKFTACVTGIPEPDFEWFHNGDKMWQTDRIRMDQEGSL 1344 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 L I NV + G YT+ N GE S L +T E Sbjct: 1345 LR----LTINNVDELDAGKYTLKISNPHGEDSCTADLIYETLE 1383 Score = 53.6 bits (123), Expect = 6e-05 Identities = 34/127 (26%), Positives = 60/127 (47%), Gaps = 3/127 (2%) Query: 478 NNYT-QYLQKKLNEKIDKLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 +N+T + L+ +L ++D E S+++ P F EK + K +G Q C G Sbjct: 2195 DNFTLRRLKHELGTRLDSYAEAEAMLESKKEGHLPFFREKPQIKPIEEGKPAQLACLAVG 2254 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 P+P I W++ +++ + ++ D D + L D G++ VA+N+ G Sbjct: 2255 SPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGSYKVVARNSLGQTVVR 2314 Query: 596 TELIVEA 602 T IVEA Sbjct: 2315 TR-IVEA 2320 Score = 51.6 bits (118), Expect = 2e-04 Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 17/188 (9%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ----VEGYPRPQITWFRQTAIIKPSQ 554 E+P + + AP F LR +H C V GYP+P++T++ I+ Sbjct: 1534 ERPPHDNYAQAPRF---LRQEHDTQYGVKNHNCNLFWFVYGYPKPKMTYYFNDQPIESGG 1590 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613 + Y + ATL I + D G + VA N G A L I E P H E T+ Sbjct: 1591 RYDQSYTRNGQATLFINRMLERDEGLYEAVASNEHGEARQRVCLRIAEYPTFIHRPEETI 1650 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGE 672 + G+P P+ ++ + + R+ + EPD + L + Sbjct: 1651 VMIRRIGQLTAR---VTGVP-----YPEIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISD 1702 Query: 673 EIVPDENI 680 +V DE + Sbjct: 1703 TMVKDEGL 1710 Score = 48.0 bits (109), Expect = 0.003 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDM 688 EG P F +KP+ + ++EG L C V P+P I W +K + +V + N I + + D Sbjct: 2225 EGHLPFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQW-YKNDMMVQETNRIKITEDQDG 2283 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 S+L K+ G+Y VVA N G+ Sbjct: 2284 R---SILSFNPTKEHDVGSYKVVARNSLGQ 2310 Score = 46.8 bits (106), Expect = 0.007 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 9/114 (7%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 +++ ARN +G ++ T +I + P P VS++ + ++W +P+ +G SP Sbjct: 2300 YKVVARNSLGQTVVRT---RIVEAFVPSGPDSPELVDVSDT---EILVRWKQPKHDGNSP 2353 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVS 1949 + Y +++K W I + HE + I N+K FR++A N +G S Sbjct: 2354 VLCYNLQYKEGDSIDWIDIAS--NIDHEFYLIRNLKADTTYNFRLAARNRIGWS 2405 Score = 45.2 bits (102), Expect = 0.020 Identities = 21/81 (25%), Positives = 41/81 (50%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 Q +V G P P+I W++ + S ++ + + + + L+I + +D G ++ A+N Sbjct: 1658 QLTARVTGVPYPEIKWYKDWKPLTTSSRIRIEFKEPDTSLLIISDTMVKDEGLYSVSARN 1717 Query: 588 AAGFASSTTELIVEAPLSDHG 608 AG S + L VE ++G Sbjct: 1718 VAGSISCSVMLHVEENEHEYG 1738 Score = 45.2 bits (102), Expect = 0.020 Identities = 25/89 (28%), Positives = 41/89 (46%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P F + Q ++E +L +P P I WY+N+ ++ + I D + ++ Sbjct: 2229 PFFREKPQIKPIEEGKPAQLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILS 2288 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARV 921 N E D G YK VA NS G++ R+ Sbjct: 2289 FNPTKEHDVGSYKVVARNSLGQTVVRTRI 2317 Score = 43.2 bits (97), Expect = 0.081 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGV 802 + +G+ L+ VG+P+P I W KN+ V+ + D D SI P K D G Sbjct: 2240 IEEGKPAQLACLAVGSPKPLIQWYKNDMMVQETNRIKITEDQDGRSILSFNPTKEHDVGS 2299 Query: 803 YTLKAENSEG 812 Y + A NS G Sbjct: 2300 YKVVARNSLG 2309 Score = 39.5 bits (88), Expect = 0.99 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKW-KXXXXXXXXXARIQKLSINTTYQ 1836 + + + + W + +G SP++ Y ++ K+ + W I+ L +TTY Sbjct: 2334 VSDTEILVRWKQPKHDGNSPVLCYNLQYKEGDSIDWIDIASNIDHEFYLIRNLKADTTYN 2393 Query: 1837 FRIYARNEIGTS 1848 FR+ ARN IG S Sbjct: 2394 FRLAARNRIGWS 2405 Score = 38.7 bits (86), Expect = 1.7 Identities = 62/281 (22%), Positives = 119/281 (42%), Gaps = 25/281 (8%) Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDE-NEIIQEKQTLEELPKEDVPEQYTITPRKSSAQ 390 K + E+ E+++ L + D V+ ++ +I++++Q+ + + + P + ++SS Sbjct: 322 KAGEEEREEVDEELEALLDRVKRQRSVLGDILEKEQSRDNILGKGQPSETDSLEKESS-- 379 Query: 391 KIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDT 450 K D I++ + ++ P I T + TV+ + V E EA +L + + D Sbjct: 380 KAD-ILERESTEESAPPHIIKSTLAD----KTVYETQTIVFEV-EATSLPRADAKWFKDG 433 Query: 451 SN-QDWWYVQKHLTEEKGWVPAQYLM--DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQS 507 + V+ + E+ + ++ DE YT KL E D + + ++ Sbjct: 434 KPLRSGERVRIESSGERFRMELSKIIIEDEGVYTCSFSNKLGE--DMTEGYLTVQTVDEL 491 Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN--- 564 P F+E L+ +G + F+ P P ITW+ + I S+D ++ DN Sbjct: 492 RRPKFIETLQDVDVANGKSGMFKAMFTADPVPDITWYFKGDEIH-SEDSRLKITVDNKPG 550 Query: 565 -------VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL 598 TL + + +D G +T KN G A S L Sbjct: 551 SDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFL 591 Score = 37.9 bits (84), Expect = 3.0 Identities = 56/293 (19%), Positives = 113/293 (38%), Gaps = 37/293 (12%) Query: 1508 VPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 +P+ W++DGK L++ + + R Y C N GE T Sbjct: 422 LPRADAKWFKDGKPLRSGERVRIESSGERFRMELSKIIIEDEGVYTCSFSNKLGEDMTEG 481 Query: 1564 VVGIQ-----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DK 1617 + +Q ++P + +D+ + G + A+ P P++ WY G+++ + D Sbjct: 482 YLTVQTVDELRRPKFIETLQDVDVAN--GKSGMFKAMFTADPVPDITWYFKGDEIHSEDS 539 Query: 1618 EYNITTKEK---------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 IT K T + + + + + +YT++ N G + L + P Sbjct: 540 RLKITVDNKPGSDKLTETTVTLSVPKCSKDDTGEYTLKLKNKYGEAESNAFLNLLLCPEI 599 Query: 1669 PEGPVIMREISRE---SVTIEWKPPLD-----DGGL--ELTKYAIEKHEPDNNRWIKVAD 1718 E + + I+ P D DG + + +Y E+ + +N + + + Sbjct: 600 QELNDVTTNVGESLAWQAIIKGNPKPDITWSKDGKVLEKGERYDFEEDKRNNKFTLVIKE 659 Query: 1719 VDRDVE-TYCIQKLN----ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 V+ D + Y + N + + + ++ P+ FSE L +P+ K DV Sbjct: 660 VEIDDKGAYQVTAKNYLGEASAQAILTPYSETPI-FSEILPKKPVECKDRSDV 711 >UniRef50_UPI00004DA303 Cluster: UPI00004DA303 related cluster; n=2; Xenopus tropicalis|Rep: UPI00004DA303 UniRef100 entry - Xenopus tropicalis Length = 2690 Score = 215 bits (525), Expect = 1e-53 Identities = 259/1098 (23%), Positives = 437/1098 (39%), Gaps = 96/1098 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PPT + + +LLEC+ AIP P I WL G ++ + V + D H Sbjct: 374 VPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRPLL--QRPGVQVIDDGH-- 429 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I + G YT A N G + I P K ++V +G Sbjct: 430 --YLQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTP-KQLMVNKGSL 486 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENS 810 V + V G P P++TW K+ P+ P +TILK + G Y A N+ Sbjct: 487 VTMECVVSGKPSPSVTWLKDGYPLGNGPDLFFQNKGQQLTILKAQP-SHSGRYVCVAVNA 545 Query: 811 EGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G + + V+ P E N + L ++ GT + T P P ITW+RN Sbjct: 546 AGQTDIKYEVFVQVPPELPNTQTELL-----NVSTSLHGTFTITCEATGIPPPVITWFRN 600 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 NE +SP E + G + + + D+G Y CV +N+AG++ V I V + Sbjct: 601 NEALSPRENVHLQSGGRVLRITHAQIQ---DAGHYTCVVTNTAGQAKKDFFVDILVPP-S 656 Query: 930 FVKHLQKSYETEEGKTVILECQTS-HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 EG++V L C+ S H W + + + D I +G Sbjct: 657 IDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPDG--SELHIQ 714 Query: 988 XXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-------V 1038 +VG CI + E S +V + I D E E + I+ Sbjct: 715 SANVFNVGHYTCIAINSIAERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICE 774 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 + V W ++GE K N GH L I N D G+Y+C++ +E A Sbjct: 775 ALGFPIPSVTWLKNGEPFKDSDN-LRLLPGGH--GLQILNAQEEDSGQYTCVVTNEVGEA 831 Query: 1099 ----EVTVVELPPEIITRLQNQKVN-KGNKATFEIELT---KGDAL----VRWFKDGSEI 1146 EV V +PP I +Q V K K LT + A+ + W+KDG + Sbjct: 832 IRNYEVKVF-IPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLL 890 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRL 1202 + S +Q+ DG Q+L++ L D+G Y+C G + + V++ Sbjct: 891 ESSGGVQILSDG--QELQLQPIRLSDSGRYTCVATNVAGEDEKEFYVNVQDDDEEELTEH 948 Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 E + + T IP L TWYK ++ ++ ++ ++ R L I Sbjct: 949 REVVATNPISLYCDTNAIPPPIL--TWYKDGQLLSSSDGVLIL--LEGRILQIPMAHAKH 1004 Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE-----REYRIKRGSDVTLLVDYQAFPQP 1317 +YTC + +L E+V P ++ E +E + L D P P Sbjct: 1005 AGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPP 1064 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD------- 1370 + W+ N + + + I ++ +L I V+ +D Y EN G A+ Sbjct: 1065 SITWLRNGLTLSTAE--RYQILNEGKTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMV 1122 Query: 1371 VEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-I 1428 E++ + + P PP + +L I S + C E E + S ++ + + + +D+ W + Sbjct: 1123 HELSFSSVRCPVPPHTRDYVLIIGKSIVLSC--EAEGS-PSPVVTSLKDGEPLDSGVWGV 1179 Query: 1429 SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 +++ ++ I ++ + + R+R A N + SET + + ++ + + E P Sbjct: 1180 AIRG---SRLQITRVQQSHAGRYRCIAQNSI-----SETHKDFVLLVQVAPRIFGSEMPS 1231 Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-------KTAKATYENRXXXXXXXXX 1541 ++ E ++++L C G P P++ W++DG L + T ++ Sbjct: 1232 EHSVPE-KQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQ 1290 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+A N+ GE V+ I PV+ S + G T G P Sbjct: 1291 ASDSGRYTCVARNNAGEDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPL 1350 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P + W K+G L + + N+ + + ++ ++ S Y+ A N AG S L Sbjct: 1351 PSLSWEKDGQPL--NLQSNLLPNGLGTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLT 1408 Query: 1662 VYDKPSKPEGPVIMREIS 1679 V + P + EGP + E+S Sbjct: 1409 VLE-PPRIEGPALPTEVS 1425 Score = 199 bits (486), Expect = 6e-49 Identities = 242/1070 (22%), Positives = 420/1070 (39%), Gaps = 78/1070 (7%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 +GS++ L C+ +P P + W G+ + P + E VL++ + +G Sbjct: 17 DGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGG-----QVLQLNGTRLSDQG 71 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESVILSAQVVGNPRP 764 Y +A N G+ L++ T PP + ++ V +V L + +P P Sbjct: 72 RYQCLAFNHAGQQVKDFNLRVHT----PPTIWASNETTEVASLLHGTVELRCEARASPVP 127 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 ITW K+ +P+ + + + L + D G YT +A N+ G AE S + V Sbjct: 128 GITWFKDKRPIVSSSRATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYRLEVYV 187 Query: 825 PTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P P + I E +TV + L T P P+I W RNN +S + + Sbjct: 188 P------PKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHEDGVEVLN 241 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942 + +L I + S DSG+Y+CVASN+AG + + ++V ++ + E+ Sbjct: 242 GVQGPKLQIESAKSS-DSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATFLVNEQ 300 Query: 943 GKTVILECQTSHT--VSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 V LEC + + W ++ +S + +I+++GR D G+ C Sbjct: 301 ---VWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGR--ILSLRAAHVSDSGIYSC 355 Query: 1000 IVKDQ--ETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVV-WERDGEI 1055 + + E S + ++ +P I + + + +LE + + ++ W +DG Sbjct: 356 VAVNPAGEDSHHIALQVFVPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDGRP 415 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEIITR 1112 + + + GH L I + D G Y+C +++ E ++ P I Sbjct: 416 LLQRPGVQVIDD-GHY--LQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAGS 472 Query: 1113 LQNQK---VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 K VNKG+ T E ++ K V W KDG + N L K Q+L I Sbjct: 473 SNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKDGYPL--GNGPDLFFQNKGQQLTILKA 530 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP--EFILVPANTDAYLTVEIPDETLD 1226 +G Y C N+ + E + LP + L+ +T + T I E Sbjct: 531 QPSHSGRYVCVAVNAAGQTDIKY-EVFVQVPPELPNTQTELLNVSTSLHGTFTITCEATG 589 Query: 1227 -----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 +TW++ + E L S R L I D YTCV+ + K Sbjct: 590 IPPPVITWFRNNEALSPRENVHLQSG--GRVLRITHAQIQDAGHYTCVVTNTAGQAKKDF 647 Query: 1282 EVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 V P +D E + R+ G VTL P+P W+ +S+ ++ S D Sbjct: 648 FVDILVPPSIDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPVQSGDEVLISPD 707 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 + L I+ + G Y N+ VT+L P+ G P E + I I Sbjct: 708 --GSELHIQSANVFNVGHYTCIAINSIAERSRSYIVTVLVSPTISG-PLDDEANEDVIVI 764 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-----QTSIQNLKTNSSYRFRAY 1454 + P + + + + + E + + I N + S ++ Sbjct: 765 V-NNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQEEDSGQYTCV 823 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 NEV + + + + + K P + +K + T+ N + L C VP+P + Sbjct: 824 VTNEVGEAIRNYEVKVF-IPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQAVPKPTLH 882 Query: 1515 WYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 WY+DG+ L+++ + Y C+A N GE E V +Q Sbjct: 883 WYKDGQLLESSGGVQILSDGQELQLQPIRLSDSGRYTCVATNVAGEDEKEFYVNVQDD-- 940 Query: 1573 ITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 E++ + +V ++ + IPPP + WYK+G L + I + + ++ Sbjct: 941 ---DEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEGR--IL 995 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREIS 1679 +I H+ KYT EA+N AG + L V P K E +++E+S Sbjct: 996 QIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVS 1045 Score = 190 bits (463), Expect = 4e-46 Identities = 223/967 (23%), Positives = 376/967 (38%), Gaps = 80/967 (8%) Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-------SITILK 793 L+ M R G V L + G PRP + W K+ +P LP GD H + L Sbjct: 10 LQDMTARDGSEVELHCKASGVPRPQVEWTKDGQP---LPP---GDAHIQLTEGGQVLQLN 63 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 ++ D+G Y A N G + V P A N E+ GT++L Sbjct: 64 GTRLSDQGRYQCLAFNHAGQQVKDFNLRVHTPPTIWAS-----NETTEVASLLHGTVELR 118 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +PVP ITW+++ I S T G +++L + D G Y C A+N+AG Sbjct: 119 CEARASPVPGITWFKDKRPIVSSSRATYREGGRSLQLSRVLLS---DVGTYTCRATNNAG 175 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD 971 + R+ + V + + + L C + T + +W N +S D Sbjct: 176 TAEKSYRLEVYVPPKVVIGEGSEHVTVTANDPLDLSCHATGYPTPTIQWLRNNHSLSHED 235 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIPEFIRKLQDFEV 1028 E++ + D G +C+ + ST L ++ P + + Sbjct: 236 GVEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQYNLLVNVAPRIVSMMDFATF 295 Query: 1029 KEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 + LE ++W +D + ++G I L +R V D G Y Sbjct: 296 LVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIAGLQIMEQGRI--LSLRAAHVSDSGIY 353 Query: 1088 SCIL---RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDG 1143 SC+ E V +PP I+ N + E + T L+ W KDG Sbjct: 354 SCVAVNPAGEDSHHIALQVFVPPTIMGEELNSSIAVNQPLLLECQSTAIPPPLITWLKDG 413 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINF 1198 + +Q+ DG L+I L DAG Y+CE N K ++ +P I Sbjct: 414 RPLLQRPGVQVIDDG--HYLQIDQAQLRDAGRYTCEASNDAGRTEKHYNVIIWAQPMIAG 471 Query: 1199 TLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 + P+ ++V N + +T+E + VTW K + + L K + L I Sbjct: 472 SSNTPKQLMV--NKGSLVTMECVVSGKPSPSVTWLKDGYPLGNGP--DLFFQNKGQQLTI 527 Query: 1256 RKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDYQA 1313 K Y CV ++A T +K EV V+ PP++ + + E + T + +A Sbjct: 528 LKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTELLNVSTSLHGTFTITCEA 587 Query: 1314 --FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 P P W N++ + ++ + S L I + DAG Y + N G A Sbjct: 588 TGIPPPVITWFRNNEALSPRENV--HLQSGGRVLRITHAQIQDAGHYTCVVTNTAGQAKK 645 Query: 1372 EMNVTILDKPSPPGK-PNILEI-DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 + V IL PS G+ N L + + S+ + + +I ++ + Q + + + + Sbjct: 646 DFFVDILVPPSIDGEDDNDLRVPEGQSVTLSCKVSGHP--KPLITWLRDSQPVQSGDEVL 703 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 + + ++ IQ+ + + A+N + +E + Y V T + SPT+ PL Sbjct: 704 I-SPDGSELHIQSANVFNVGHYTCIAINSI-----AERSRSYIV---TVLVSPTISGPLD 754 Query: 1490 NITTEP-----NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX 1542 + E N L C G P P VTW ++G+ K + Sbjct: 755 DEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQE 814 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDI---KQKHKVGDEWLVTAVIE 1597 Y C+ N+ GE + V + PVI ++D+ + K KV + + Sbjct: 815 EDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQCESQ 874 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 +P P + WYK+G LE+ I + + ++++ ++ S S +YT A+N AG E Sbjct: 875 AVPKPTLHWYKDGQLLESSGGVQILSDGQE--LQLQPIRLSDSGRYTCVATNVAGEDEKE 932 Query: 1658 VTLKVYD 1664 + V D Sbjct: 933 FYVNVQD 939 Score = 190 bits (462), Expect = 5e-46 Identities = 230/1054 (21%), Positives = 424/1054 (40%), Gaps = 87/1054 (8%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 + C IP P I W E + P EN+ + VL+IT+ + G YT V Sbjct: 583 ITCEATGIPPPVITWFRNNEALSPRENVHLQSGG------RVLRITHAQIQDAGHYTCVV 636 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 N G+A + I PP + E + V +G+SV LS +V G+P+P ITW ++ Sbjct: 637 TNTAGQAKKDFFVDILV----PPSIDGEDDNDLRVPEGQSVTLSCKVSGHPKPLITWLRD 692 Query: 772 NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 ++PV++ S ++ V + G YT A NS IAE S V Sbjct: 693 SQPVQSGDEVLISPDGSELHIQSANVFNVGHYTCIAINS--IAERSRSYIVTVLVSPTIS 750 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 PL +++ V L+ P+PS+TW +N E S+ + G ++++ Sbjct: 751 GPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQIL 810 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI---- 947 N E DSG Y CV +N G++ V + + V + +E KT + Sbjct: 811 --NAQEE-DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSL 867 Query: 948 -LECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 L+C++ + WY + + + +I+ +G+ D G C+ + Sbjct: 868 TLQCESQAVPKPTLHWYKDGQLLESSGGVQILSDGQELQLQPIRLS--DSGRYTCVATN- 924 Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKE-----KDVAILEVEINSETADV-----VWERDGE 1054 V E EF +QD + +E + VA + + +T + W +DG+ Sbjct: 925 ------VAGEDEKEFYVNVQDDDEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQ 978 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPP---- 1107 ++ + G I L I G+Y+C +E+ + VV PP Sbjct: 979 LLSSSDGVLILLE-GRI--LQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKG 1035 Query: 1108 EIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 E+ +Q V A + + + W ++G + + Q+ +GK L+I+ Sbjct: 1036 EVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLSTAERYQILNEGKT--LQIH 1093 Query: 1167 DCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFT-LRLP------EFILVPANTDAYLT 1217 + D Y C N A + T+ ++F+ +R P +++L+ + L+ Sbjct: 1094 SVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRDYVLIIGKS-IVLS 1152 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 E V K D+ + + ++ L I + + Y C+ ++ S T Sbjct: 1153 CEAEGSPSPVVTSLKDGEPLDSGVWGVA--IRGSRLQITRVQQSHAGRYRCIAQNSISET 1210 Query: 1278 -KLKVEVVEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCK 1332 K V +V+ P+I E E+ + +V L + P P W N + Sbjct: 1211 HKDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVP 1270 Query: 1333 HTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 +T ++ + + L ++ V+ +D+G Y NN G + IL P + E Sbjct: 1271 NTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLNILGLPVLERSESTEE 1330 Query: 1392 IDS-SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 + + ++ + + + + + Q ++ + + N T+ +++++ S Sbjct: 1331 VTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNL-LPNGLGTRLHLESVRALDSGI 1389 Query: 1451 FRAYAVNEVDISDASETTEYYK--VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 + AVN A ++++ V++ +I+ P + + I P +EL C GV Sbjct: 1390 YSCIAVNA-----AGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSP---LELACTATGV 1441 Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 P P+++W +DG+ L N Y C+A + G + V ++ Sbjct: 1442 PTPEISWEKDGRPLSHPDLLTRNGTVLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMK 1501 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 P + S E VG + ++ +E PPP + WY+ L+ D + +K + Sbjct: 1502 VPPSVVGSTEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDIPLQTDGRVQVLSKGR-- 1559 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++I L+ S S +YT ASN AG +S+ T+++ Sbjct: 1560 YVQIHSLRPSDSGEYTCIASNPAGRTSLHFTVEI 1593 Score = 170 bits (413), Expect = 4e-40 Identities = 254/1189 (21%), Positives = 460/1189 (38%), Gaps = 128/1189 (10%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 DGS V+ C+ G PRPQ+ W + + P + V L + D G + Sbjct: 17 DGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQV--LQLNGTRLSDQGRYQ 74 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C+A N AG L V P + S T A +L G Sbjct: 75 CLAFNHAGQQVKDFNLRVHTPPTIWASNET----------TEVASLLHG----------- 113 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 + L C A P P I W FK + + + + E + S + +++V Sbjct: 114 -------TVELRCEARASPVPGITW-FKDKRPIVSSSRATYREGGRSLQLSRVLLSDV-- 163 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVG 760 GTYT A N G A L++ PP+V+ E + + V + + LS G Sbjct: 164 ---GTYTCRATNNAGTAEKSYRLEVYV----PPKVVIGEGSEHVTVTANDPLDLSCHATG 216 Query: 761 NPRPTITWCKNNKPVKALPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P PTI W +NN + +G ++ K D G Y A N+ G E Sbjct: 217 YPTPTIQWLRNNHSLSHEDGVEVLNGVQGPKLQIESAKSSDSGEYRCVASNTAGSTELQY 276 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V N P + ++ T + L T P P+I W ++ +S + Sbjct: 277 NLLV------NVAPRI-VSMMDFATFLVNEQVWLECNATGVPEPAIMWLKDQVPVSTAIA 329 Query: 879 ITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 Q + G + L +V DSG Y CVA N AG+ SH + + V + L S Sbjct: 330 GLQIMEQGRILSLRAAHVS---DSGIYSCVAVNPAGEDSHHIALQVFVPPTIMGEELNSS 386 Query: 938 YETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + ++LECQ++ W + + + ++I +G D G Sbjct: 387 IAVNQ--PLLLECQSTAIPPPLITWLKDGRPLLQRPGVQVIDDGH--YLQIDQAQLRDAG 442 Query: 996 VIKCIVK------DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVV 1048 C ++ + ++ + I + V + + +E ++ + + V Sbjct: 443 RYTCEASNDAGRTEKHYNVIIWAQPMIAGSSNTPKQLMVNKGSLVTMECVVSGKPSPSVT 502 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVEL 1105 W +DG + + + F+ +G ++L I G Y C+ + + ++ V++ Sbjct: 503 WLKDGYPLGNGPDLF-FQNKG--QQLTILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQV 559 Query: 1106 PPEI---ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 PPE+ T L N + T E T ++ WF++ + ++ L G+ Sbjct: 560 PPELPNTQTELLNVSTSLHGTFTITCEATGIPPPVITWFRNNEALSPRENVHLQSGGR-- 617 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYL 1216 L+I + DAG Y+C V N+ A + + PSI+ + VP L Sbjct: 618 VLRITHAQIQDAGHYTCVVTNTAGQAKKDFFVDILVPPSIDG--EDDNDLRVPEGQSVTL 675 Query: 1217 TVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--A 1273 + ++ +TW + ++ ++ + D + L I+ + YTC+ ++ A Sbjct: 676 SCKVSGHPKPLITWLRDSQPVQSGDEVLISPDGSE--LHIQSANVFNVGHYTCIAINSIA 733 Query: 1274 KSTTKLKVEVVEFP----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + + V V+ P P + + + + +L+ + FP P+ W+ N + K Sbjct: 734 ERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFK 793 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNV---TILDKPSPP 1384 + + + L I + D+G Y + N G A + E+ V ++ + P Sbjct: 794 DSDNLR--LLPGGHGLQILNAQEEDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPH 851 Query: 1385 GKPNILEID---SSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 I E+ +SS+ + C E + T+ +Y + Q ++++ + + + + + Sbjct: 852 QDVGIKEVKTKVNSSLTLQC--ESQAVPKPTLHWY-KDGQLLESSGGVQILS-DGQELQL 907 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 Q ++ + S R+ A N + E+Y +++ + T + + + T P I Sbjct: 908 QPIRLSDSGRYTCVATNVA----GEDEKEFYVNVQDDDEEELTEHREV--VATNP---IS 958 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 L C +P P +TWY+DG+ L ++ E R Y C A N+ G Sbjct: 959 LYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEGR-ILQIPMAHAKHAGKYTCEATNEAG 1017 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 E + + PV+ +++ Q+ V + GIPPP + W +NG L Sbjct: 1018 EDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLST 1077 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 + Y I + KT ++I ++ S Y A N AG + TL V++ Sbjct: 1078 AERYQILNEGKT--LQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHE 1124 Score = 164 bits (399), Expect = 2e-38 Identities = 231/1079 (21%), Positives = 426/1079 (39%), Gaps = 94/1079 (8%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S PK V++GS + +EC + P P + WL G + ++ + L Sbjct: 473 SNTPKQLMVNKGSLVTMECVVSGKPSPSVTWLKDGYPLGNGPDLFFQNKGQQ------LT 526 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 I + G Y VAVN G+ + + ++ + P E L G I + Sbjct: 527 ILKAQPSHSGRYVCVAVNAAGQTDIKYEVFVQVPPELPNTQTELLNVSTSLHGTFTI-TC 585 Query: 757 QVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 + G P P ITW +NN+ P + + +S G IT +++D G YT N+ G Sbjct: 586 EATGIPPPVITWFRNNEALSPRENVHLQSGGRVLRIT---HAQIQDAGHYTCVVTNTAGQ 642 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A+ + + P + E ++ V E ++ L +V+ +P P ITW R+++ + Sbjct: 643 AKKDFFVDILVPPSIDGEDD------NDLRVPEGQSVTLSCKVSGHPKPLITWLRDSQPV 696 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + + + DG + + NV + G Y C+A NS + S VT+ V Sbjct: 697 QSGDEVLISPDGSELHIQSANV---FNVGHYTCIAINSIAERSRSYIVTVLVSPTISGPL 753 Query: 934 LQKSYE-----TEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 ++ E ++I E S W N + D+ ++ G Sbjct: 754 DDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPFKDSDNLRLLPGGHGLQILNAQ 813 Query: 989 XXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK---LQDF---EVKEKDVAILEVEI 1040 D G C+V ++ E VK IP I++ QD EVK K + L ++ Sbjct: 814 EE--DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPHQDVGIKEVKTKVNSSLTLQC 871 Query: 1041 NSETAD---VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 S+ + W +DG++++ G ++L ++ + D G Y+C+ + + Sbjct: 872 ESQAVPKPTLHWYKDGQLLE-SSGGVQILSDG--QELQLQPIRLSDSGRYTCVATNVAGE 928 Query: 1098 AE----VTVVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHI 1152 E V V + E +T ++++V N + + ++ W+KDG + S+ + Sbjct: 929 DEKEFYVNVQDDDEEELT--EHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGV 986 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSI--NFTLRLPEFI 1206 + ++G+ L+I AG+Y+CE G + L V P + L + + Sbjct: 987 LILLEGRI--LQIPMAHAKHAGKYTCEATNEAGEDRLHYELVVLTPPVMKGEVDELIQEV 1044 Query: 1207 LVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 V N A L + IP + +TW + + E++ ++++ K TL I D Sbjct: 1045 SVIYNQTAELHCDASGIPPPS--ITWLRNGLTLSTAERYQILNEGK--TLQIHSVQVSDI 1100 Query: 1264 CEYTCVLLD----AKSTTKLKVEVVEFPP---KIVDYEREYRIKRGSDVTLLVDYQAFPQ 1316 Y CV + A+ L V + F + + R+Y + G + L + + P Sbjct: 1101 DSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRDYVLIIGKSIVLSCEAEGSPS 1160 Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMN 1374 P + + K + + + + L I +V+ + AG Y+ +N+ H D + Sbjct: 1161 PV---VTSLKDGEPLDSGVWGVAIRGSRLQITRVQQSHAGRYRCIAQNSISETHKDFVLL 1217 Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NI 1433 V + + P+ + + E T I+++ + +D T + N+ Sbjct: 1218 VQVAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQILWFK-DGNPLDVTLVPNTSGNL 1276 Query: 1434 TKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 TK + +++++ + S R+ A N +A E T Y V+ + + + Sbjct: 1277 TKQDGNFLVLRSVQASDSGRYTCVARN-----NAGEDTRVY-VLNILGLPVLERSESTEE 1330 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX--Y 1548 +T + TC G P P ++W +DG+ L N Y Sbjct: 1331 VTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVRALDSGIY 1390 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 CIA N G V + + + P I + + G+P PE+ W K Sbjct: 1391 SCIAVNAAGRVSKHFHLTVLEPPRIEGPALPTEVSIIADSPLELACTATGVPTPEISWEK 1450 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +G L + ++ T+ T V+RI+ +K + Y A++TAG S +++ PS Sbjct: 1451 DGRPLSHP---DLLTRNGT-VLRIERVKAEDAGIYVCVATSTAGRDSRATWVRMKVPPS 1505 Score = 128 bits (308), Expect = 2e-27 Identities = 184/824 (22%), Positives = 308/824 (37%), Gaps = 64/824 (7%) Query: 599 IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECR 656 I A + D G V DIL +PP+ + V EG + L C+ Sbjct: 621 ITHAQIQDAGHYTCVVTNTAGQAKKDFFVDIL--VPPSIDGEDDNDLRVPEGQSVTLSCK 678 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + P+P I WL + + + + ++ + S L I + F G YT +A+N Sbjct: 679 VSGHPKPLITWLRDSQPVQSGDEVLISPDG------SELHIQSANVFNVGHYTCIAINSI 732 Query: 717 GEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 E S ++ + P E + +IV L + +G P P++TW KN +P Sbjct: 733 AERSRSYIVTVLVSPTISGPLDDEANEDVIVIVNNPFSLICEALGFPIPSVTWLKNGEPF 792 Query: 776 KALPT-KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 K + H + IL ++ +D G YT N G A + + V P + P Sbjct: 793 KDSDNLRLLPGGHGLQILNAQE-EDSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDDPH 851 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 +E+ K ++ L P P++ WY++ +++ S + DG+ ++L Sbjct: 852 QDVGIKEVKTKVNSSLTLQCESQAVPKPTLHWYKDGQLLESSGGVQILSDGQELQLQPIR 911 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 + DSG Y CVA+N AG+ V + + + L + E + L C T+ Sbjct: 912 LS---DSGRYTCVATNVAGEDEKEFYVNVQDDD---EEELTEHREVVATNPISLYCDTNA 965 Query: 955 TVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML-- 1010 WY + + +S D I+ EGR G C ++ L Sbjct: 966 IPPPILTWYKDGQLLSSSDGVLILLEGR--ILQIPMAHAKHAGKYTCEATNEAGEDRLHY 1023 Query: 1011 -VVKETIP----EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYD 1064 +V T P E +Q+ V A L + + + W R+G + + +Y Sbjct: 1024 ELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLRNGLTLSTAE-RYQ 1082 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-----------VTVVELPPEIITRL 1113 G + L I + V D Y C+ + + AE + V P TR Sbjct: 1083 ILNEG--KTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSVRCPVPPHTRD 1140 Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 + K + E E +V KDG + S + I G +L+I A Sbjct: 1141 YVLIIGKSIVLSCEAE-GSPSPVVTSLKDGEPLD-SGVWGVAIRG--SRLQITRVQQSHA 1196 Query: 1174 GEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DV 1227 G Y C NS K +L P I F +P VP + L + + Sbjct: 1197 GRYRCIAQNSISETHKDFVLLVQVAPRI-FGSEMPSEHSVPEKQEVKLECKTEGTPAPQI 1255 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRT---LIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEV 1283 W+K + ++ T ++ K+ L++R D YTCV +A T++ V Sbjct: 1256 LWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLN 1315 Query: 1284 VEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + P + E E +G+ VT + P P+ W + + + + P + Sbjct: 1316 ILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNLLP--NGL 1373 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 L ++ V D+GIY N G ++T+L+ P G Sbjct: 1374 GTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVLEPPRIEG 1417 Score = 99 bits (238), Expect = 7e-19 Identities = 145/662 (21%), Positives = 252/662 (38%), Gaps = 47/662 (7%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 I L C AIP P + W G+ + + + + +E +L+I G YT Sbjct: 957 ISLYCDTNAIPPPILTWYKDGQLLSSSDGVLILLEG------RILQIPMAHAKHAGKYTC 1010 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A N GE L L + T +V E ++ + V ++ L G P P+ITW + Sbjct: 1011 EATNEAGEDRLHYELVVLTPPVMKGEVDELIQEVSVIYNQTAELHCDASGIPPPSITWLR 1070 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 N + + + +V D Y AEN G AE + V E + + Sbjct: 1071 NGLTLSTAERYQILNEGKTLQIHSVQVSDIDSYVCVAENPAGFAERLFTLMVHELSFSSV 1130 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P+ + + + K +I L +P P +T ++ E P ++ L Sbjct: 1131 RCPVPPHTRDYVLIIGK-SIVLSCEAEGSPSPVVTSLKDGE---PLDSGVWGVAIRGSRL 1186 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 IT V +G Y+C+A NS ++ + + V F + + E + V LEC Sbjct: 1187 QITRVQQS-HAGRYRCIAQNSISETHKDFVLLVQVAPRIFGSEMPSEHSVPEKQEVKLEC 1245 Query: 951 QTSHTVSTK--WYH--NKKEISGMDHRE-IIQEGRXXXXXXXXXXXXDVGVIKCIVKD-- 1003 +T T + + W+ N +++ + + + + D G C+ ++ Sbjct: 1246 KTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDGNFLVLRSVQASDSGRYTCVARNNA 1305 Query: 1004 -QETSTMLVVKETIPEFIRKLQDFEV---KEKDVAILEVEINSETADVVWERDGEIIKPK 1059 ++T ++ +P R EV K V + + WE+DG+ + + Sbjct: 1306 GEDTRVYVLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQ 1365 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELPPEIITRLQN 1115 N G +L++ + D G YSCI + + +TV+E PP I Sbjct: 1366 SNLLP---NGLGTRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVLE-PPRIEGPALP 1421 Query: 1116 QKVNKGNKATFEIELTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 +V+ + E+ T + W KDG + S+ LT +G L+I +D Sbjct: 1422 TEVSIIADSPLELACTATGVPTPEISWEKDGRPL--SHPDLLTRNGTV--LRIERVKAED 1477 Query: 1173 AGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLD 1226 AG Y C + S+ T + PS+ + P + V L ++ D Sbjct: 1478 AGIYVCVATSTAGRDSRATWVRMKVPPSVVGSTE-PRSLAVSVGGQLVLECKVEADPPPT 1536 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 + WY+ ++ + ++S K R + I D EYTC+ + T L VE Sbjct: 1537 IQWYRGDIPLQTDGRVQVLS--KGRYVQIHSLRPSDSGEYTCIASNPAGRTSLHF-TVEI 1593 Query: 1287 PP 1288 P Sbjct: 1594 QP 1595 Score = 98.7 bits (235), Expect = 2e-18 Identities = 90/380 (23%), Positives = 155/380 (40%), Gaps = 25/380 (6%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI----VPDENISVAIESDMHMYC 692 S+ P V E ++ LEC+ P P I W G + VP+ + ++ + Sbjct: 1227 SEMPSEHSVPEKQEVKLECKTEGTPAPQILWFKDGNPLDVTLVPNTSGNLTKQDG----- 1281 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + L + +V+ G YT VA N GE + VL I + E + + +G SV Sbjct: 1282 NFLVLRSVQASDSGRYTCVARNNAGEDTRVYVLNILG--LPVLERSESTEEVTAIKGASV 1339 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + + G P P+++W K+ +P+ + L+ + D G+Y+ A N+ G Sbjct: 1340 TFTCEAHGTPLPSLSWEKDGQPLNLQSNLLPNGLGTRLHLESVRALDSGIYSCIAVNAAG 1399 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 +TV EP E P E+++ ++L T P P I+W ++ Sbjct: 1400 RVSKHFHLTVLEPPR--IEGPALPT---EVSIIADSPLELACTATGVPTPEISWEKDGRP 1454 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 +S + +T+N L I V +E D+G Y CVA+++AG+ S V + V Sbjct: 1455 LSHPDLLTRN----GTVLRIERVKAE-DAGIYVCVATSTAGRDSRATWVRMKVPPSVVGS 1509 Query: 933 HLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 +S G ++LEC + + +WY + +++ +GR Sbjct: 1510 TEPRSLAVSVGGQLVLECKVEADPPPTIQWYRGDIPLQTDGRVQVLSKGR--YVQIHSLR 1567 Query: 991 XXDVGVIKCIVKDQETSTML 1010 D G CI + T L Sbjct: 1568 PSDSGEYTCIASNPAGRTSL 1587 Score = 79.8 bits (188), Expect = 8e-13 Identities = 99/431 (22%), Positives = 178/431 (41%), Gaps = 60/431 (13%) Query: 508 MAP-IFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 +AP IF ++ +H+ P+ V+ EC+ EG P PQI +++ D N Sbjct: 1220 VAPRIFGSEMPSEHSVPEKQEVKLECKTEGTPAPQI----------------LWFKDGNP 1263 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 + + P +G T K F ++ SD G V Sbjct: 1264 LDVTL---VPNTSGNLT---KQDGNFL-----VLRSVQASDSGRYTCVARNNAGEDTRVY 1312 Query: 626 ADILEGIPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 + G+P S+ + +G+ + C P P ++W G+ + N+ + Sbjct: 1313 VLNILGLPVLERSESTEEVTAIKGASVTFTCEAHGTPLPSLSWEKDGQPLNLQSNL---L 1369 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKS 743 + + + L + +V+ G Y+ +AVN G S L + EPP++ P L + Sbjct: 1370 PNGLG---TRLHLESVRALDSGIYSCIAVNAAGRVSKHFHLTVL----EPPRIEGPALPT 1422 Query: 744 MIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800 + +S + L+ G P P I+W K+ +P+ + D T + T+L+ ++VK D Sbjct: 1423 EVSIIADSPLELACTATGVPTPEISWEKDGRPL----SHPDLLTRNGTVLRIERVKAEDA 1478 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEE--NAEPPLFINRFQEITVKEKGTIKLVARVTR 858 G+Y A ++ G + + ++ P + EP + + V G + L +V Sbjct: 1479 GIYVCVATSTAGRDSRATWVRMKVPPSVVGSTEP-------RSLAVSVGGQLVLECKVEA 1531 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 +P P+I WYR + + + G +++ DSG+Y C+ASN AG++S Sbjct: 1532 DPPPTIQWYRGDIPLQTDGRVQVLSKGRYVQIHSLRPS---DSGEYTCIASNPAGRTSLH 1588 Query: 919 ARVTIDVEKVT 929 V I T Sbjct: 1589 FTVEIQPHSAT 1599 Score = 72.9 bits (171), Expect = 9e-11 Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 11/208 (5%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXXXX 1544 L+++T ++EL C GVP+P+V W +DG+ L A E Sbjct: 10 LQDMTARDGSEVELHCKASGVPRPQVEWTKDGQPLPPGDAHIQLTEGGQVLQLNGTRLSD 69 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y+C+AFN G+ + + P I SNE + + + P P + Sbjct: 70 QGRYQCLAFNHAGQQVKDFNLRVHTPPTIWASNETTEVASLLHGTVELRCEARASPVPGI 129 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W+K+ + + T +E +++ + S YT A+N AGT+ L+VY Sbjct: 130 TWFKDKRPIVSSS--RATYREGGRSLQLSRVLLSDVGTYTCRATNNAGTAEKSYRLEVYV 187 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLD 1692 P V++ E S E VT+ PLD Sbjct: 188 PPK-----VVIGEGS-EHVTVTANDPLD 209 Score = 48.8 bits (111), Expect = 0.002 Identities = 46/191 (24%), Positives = 78/191 (40%), Gaps = 13/191 (6%) Query: 476 DENNYTQYLQKKLNEKID--KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 D YT + ++ E I ++ VF P + P ++ T S++ +C+ Sbjct: 816 DSGQYTCVVTNEVGEAIRNYEVKVFIPPVIKRDD--PHQDVGIKEVKTKVNSSLTLQCES 873 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 + P+P + W++ +++ S Q+ D L ++ + D+G +TCVA N AG Sbjct: 874 QAVPKPTLHWYKDGQLLESSGGVQILSDGQE---LQLQPIRLSDSGRYTCVATNVAG--E 928 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP---TFSKKPKAQYVDEGSD 650 E V D E+T IPP T+ K + +G Sbjct: 929 DEKEFYVNVQ-DDDEEELTEHREVVATNPISLYCDTNAIPPPILTWYKDGQLLSSSDGVL 987 Query: 651 ILLECRLVAIP 661 ILLE R++ IP Sbjct: 988 ILLEGRILQIP 998 Score = 46.0 bits (104), Expect = 0.011 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 9/95 (9%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P+G +V C+V G+P+P ITW R + ++ S D + D + + VF + G + Sbjct: 668 PEGQSVTLSCKVSGHPKPLITWLRDSQPVQ-SGDEVLISPDGSELHIQSANVF--NVGHY 724 Query: 582 TCVAKNAAGFASST---TELI---VEAPLSDHGSE 610 TC+A N+ S + T L+ + PL D +E Sbjct: 725 TCIAINSIAERSRSYIVTVLVSPTISGPLDDEANE 759 >UniRef50_UPI0000E460A7 Cluster: PREDICTED: similar to OTTHUMP00000065631; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to OTTHUMP00000065631 - Strongylocentrotus purpuratus Length = 3664 Score = 214 bits (522), Expect = 3e-53 Identities = 251/1069 (23%), Positives = 440/1069 (41%), Gaps = 86/1069 (8%) Query: 635 TFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 T SK P V + I L+C + A P P I W +KG+E + + +V I+ D + Sbjct: 2359 TGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKW-YKGDETLTGQEEAVTIK-DQGI--- 2413 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESV 752 L+I +V G Y A N G AS+ + ++ P ++ + Q + Sbjct: 2414 TLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQV----TPSILNGQDEYLTTVQNIDI 2469 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSE 811 L + GNP PTITW ++NKP++ + G+ S+ I P+ D G Y A N+ Sbjct: 2470 TLLCEAEGNPTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQHT-DSGGYVCVASNNI 2528 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G A + + V+ P + + + + +T+ + ++ L + P P+I+W ++N Sbjct: 2529 GYAIKNFHLVVKIPPKTSTQQEV-------VTIGLRQSVTLRCQAAGFPAPTISWRKDNL 2581 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 I P T + L I N E DSG Y C+ASN G+ S + + + Sbjct: 2582 PI-PLSTRAFSISSNGGSLTI-NSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPIILG 2639 Query: 932 K---HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXX 986 + + + + EG + L C T+ + W+ + + +S +++ I +G Sbjct: 2640 ELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPPEYK-IKDDG---TLVI 2695 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQ--DFEVKEKDVAIL--EVE 1039 D GV C ++ ++ + + T+ P + + D V + A L E++ Sbjct: 2696 PGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEID 2755 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 I+ A +VW++DG ++ N + G I L I V++EG Y+CI + + A Sbjct: 2756 ISIPMASIVWQKDGISLREDSN-IRISRDGQI--LEINQVQVNNEGRYTCIATNNAGNAT 2812 Query: 1100 V---TVVELPPEII----TRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNH 1151 V +PP +N+ + + +RW+KDG + N Sbjct: 2813 KFFGLTVHVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTH-NE 2871 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE-EPSINFTLRLPEFI 1206 + + + L+I + AG+++C VGN + +L V P I P + Sbjct: 2872 PGVAVSNSGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGA-EFPHNV 2930 Query: 1207 LVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 V N L TV IP ++ WYK + + LIS TL I D+ Sbjct: 2931 SVVNNMGIELRCPTVAIP--VPEIVWYKDGHRLHPFQSGVLISP-DGTTLRIPNAQLHDE 2987 Query: 1264 CEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEW 1321 Y CV + A KL ++ PP IV E + + G T+ + P+P W Sbjct: 2988 GVYQCVATNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTW 3047 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 N+ I + ID + L I V D G+++ + N+ G+ +++ + +P Sbjct: 3048 TKNNAFISPAS-IRYDIDP-AGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQP 3105 Query: 1382 S-PPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTS 1439 + PG+ + S+ + D TG T I + + Q + E + I+ Sbjct: 3106 TITPGRGRVTTQIGQSVRLFCDA---TGVPTPEILWQKDGQRVSPMEGFLI--ISDGMLQ 3160 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I + + + + R+ A N + +KVI E + P + + K + + Sbjct: 3161 INDAQPSDAGRYDCIAKNGAG-------ADVFKVILEVH-EPPQIAETTKTYEIRVDASV 3212 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 EL C GG+P+P + W +G++L N Y C+A ND G Sbjct: 3213 ELECRVGGIPKPNIRWLFNGRELGAQSLKLAN-GNLKIPVVRAEDSGAYTCLAQNDAGFA 3271 Query: 1560 ETSCVVGIQQKPVI-TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + ++ + P + E + V ++T +G PPPEV W K+G +E Sbjct: 3272 QAERILVVLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAGR 3331 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +T + + R++E S S YT A+N+ G++ + L V P+ Sbjct: 3332 ITMTENHELIIDRVQE---SDSGTYTCVATNSIGSNRLNFYLTVQVAPT 3377 Score = 186 bits (452), Expect = 8e-45 Identities = 233/1073 (21%), Positives = 412/1073 (38%), Gaps = 96/1073 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 IPP S + + + + L C+ P P I+W K +P + +I S+ Sbjct: 2541 IPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWR-KDNLPIPLSTRAFSISSNG--- 2596 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR---- 747 L I + ++ G Y+ +A N GE SL I+LK++ EPP ++ L+ ++ Sbjct: 2597 -GSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQ----EPPIILGELEVNRMQHVQL 2651 Query: 748 -QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTL 805 +G+ + L G P+P + W ++N+ + K D T++ P + D GVYT Sbjct: 2652 VEGDDIELPCPTTGYPKPRVAWFRDNRILSPPEYKIKDDG---TLVIPGAMPFDAGVYTC 2708 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ--EITVKEKGTIKLVARVTRN-PVP 862 A N G + S +TV PPL ++ ++ +I V +L + + P+ Sbjct: 2709 SAVNEAGNSSISINVTV-------MVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMA 2761 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 SI W ++ + I + DG+ +E+ V++E G Y C+A+N+AG ++ +T Sbjct: 2762 SIVWQKDGISLREDSNIRISRDGQILEINQVQVNNE---GRYTCIATNNAGNATKFFGLT 2818 Query: 923 IDVEKV----TFVKHLQKSYETEEGKTVILECQTSHTVSTKWY-------HNKKEISGMD 971 + V + V + S ++ + + +WY HN+ ++ + Sbjct: 2819 VHVPPIFPDGNPVNPMMMSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSN 2878 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 E+++ R ++ I K + + + EF + V Sbjct: 2879 SGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVS--VVNNM 2936 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 + + + ++VW +DG + P ++ G L I N +HDEG Y C+ Sbjct: 2937 GIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPDG--TTLRIPNAQLHDEGVYQCVA 2994 Query: 1092 RD---ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIE-LTKGDALVRWFKDGSEI 1146 + E +++PP I++R NQ V G T + E V W K+ + I Sbjct: 2995 TNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAFI 3054 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF 1205 ++ I+ ID L I + D G + C V NS ++ + + T+ Sbjct: 3055 SPAS-IRYDID-PAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRG 3112 Query: 1206 -ILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + L + T ++ W K + E F +ISD L I D Sbjct: 3113 RVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISD---GMLQINDAQPSDA 3169 Query: 1264 CEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 Y C+ + KV + V PP+I + + Y I+ + V L P+PN W+ Sbjct: 3170 GRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDASVELECRVGGIPKPNIRWL 3229 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 N + + S+ + +L I V D+G Y +N+ G A E + +LD P Sbjct: 3230 FNGRELGA-----QSLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLDVPR 3284 Query: 1383 PPGKPN-----ILEIDSSSINIC----WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433 P P + ++ ++ C + PE T I V I TE Sbjct: 3285 LPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGIL-VEPAGRITMTE------- 3336 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 + I ++ + S + A N + S +Y ++ +PT ++ Sbjct: 3337 -NHELIIDRVQESDSGTYTCVATNSI----GSNRLNFYLTVQV----APTFTHFPNDVEL 3387 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 +EL C GVP P + W +G ++ T++ R Y C A Sbjct: 3388 AAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSVLAIGNVQKSDSGTYMCRAE 3447 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N G V ++ P I D +G+ ++ + G P PEV W KN + Sbjct: 3448 NILGVRTAITAVRVRVPPRIHRIPSDTTL--TLGERAVLNCAVNGDPKPEVTWLKNNRPV 3505 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + + I S + Y +A N G V L++ +P Sbjct: 3506 ALT---DTMQQSSDGSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRP 3555 Score = 185 bits (451), Expect = 1e-44 Identities = 238/1090 (21%), Positives = 426/1090 (39%), Gaps = 80/1090 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP S P G ++ L C + +P P W G ++ D++ ++ Sbjct: 1798 VPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDEGS--- 1854 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQ 748 L I++V++ G Y + VN+ G + I L +K + E P+V+E + + VR Sbjct: 1855 ---LIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVR- 1910 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLK 806 + Q G PRP ++W K+ +P++ L T +T I+ L+P D G Y + Sbjct: 1911 -----IPCQATGTPRPQVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPY---DNGRYECR 1962 Query: 807 AENSEGIAETSAVITVE-EPT---EENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPV 861 A++ G I + P E + P+ + F E E T+ L VT +P Sbjct: 1963 AQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVV--FTE----EDQTVILECNVTDSHPP 2016 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 +TWY+N + I I +F+ + L + + E D+G Y C A+N G S + Sbjct: 2017 AEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPE-DAGHYHCEATNGQGSSQRHFSL 2075 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979 + V V Q+ + G ++ + C+ S + W IS + R I Sbjct: 2076 EVHVGPV-IRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAISSQNSRYHIASN 2134 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAIL 1036 D GV CI K+ + VV + P D IL Sbjct: 2135 --GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTSDIVRTLSSSVIL 2192 Query: 1037 EVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 E ++ W ++G + + G +R IR+ D G Y C+ +++ Sbjct: 2193 PCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSLR---IRSVEEEDSGVYRCVAVNQA 2249 Query: 1096 --CTAEVTV-VELPPEI-ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS- 1149 +T+ + PP + +N K ++ RW K+ E+ + Sbjct: 2250 GHDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNY 2309 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINFTLRLPE 1204 ++L DG L I D + D G Y+CE N S+ + P I + E Sbjct: 2310 GKMELLEDG---SLMIRDVESIDRGSYTCEATNAVGVLSRDIRLEVSVAPKITGSKTPVE 2366 Query: 1205 FILVPANT---DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 + + ++ +T P + WYK + E+ I D + TL I Sbjct: 2367 YPVGQYDSIELQCMVTDAFPPPI--IKWYKGDETLTGQEEAVTIKD-QGITLEIGSVNIA 2423 Query: 1262 DQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPND 1319 + EY C + + + V+ P I++ + EY + D+TLL + + P P Sbjct: 2424 NAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTI 2483 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 W ++K ++ + + SL I ++TD+G Y NN G+A ++ + Sbjct: 2484 TWERDNKPLE--LRDSHYLIGEDGSLRITAPQHTDSGGYVCVASNNIGYAIKNFHLVVKI 2541 Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 P + ++ I + TI + +T S+ + + T Sbjct: 2542 PPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRAFSISSNGGSLT- 2600 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLKNITTEPNED 1498 I + + S + A NEV ++ + ++E I +E ++++ +D Sbjct: 2601 INSTREGDSGIYSCIASNEV----GEQSLDILLKVQEPPIILGELEVNRMQHVQLVEGDD 2656 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 IEL C G P+P+V W+RD + L + ++ Y C A N+ G Sbjct: 2657 IELPCPTTGYPKPRVAWFRDNRILSPPEYKIKDDGTLVIPGAMPFDAGVYTCSAVNEAGN 2716 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDK 1617 S V + P++ + + + + + I+ IP ++W K+G L D Sbjct: 2717 SSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGISLREDS 2776 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG-PV--I 1674 NI ++ I +++ ++ +YT A+N AG ++ L V+ P P+G PV + Sbjct: 2777 --NIRISRDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGNPVNPM 2834 Query: 1675 MREISRESVT 1684 M I+ + T Sbjct: 2835 MMSINEDDST 2844 Score = 178 bits (434), Expect = 1e-42 Identities = 236/1086 (21%), Positives = 424/1086 (39%), Gaps = 96/1086 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+ S + V + L C P P I W+ G+ I ++ ++ Sbjct: 1073 PPSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIKNGQTI-----------PNLGLHQ 1121 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIVRQGE 750 S L ++ V + GTY N G + + I L I PP + +E + V QG+ Sbjct: 1122 SALTLSYVTEQDAGTYICRVSNLAGFSEIEITLFILV----PPAHEGVETTGVVNVTQGD 1177 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 SV L V G P P I+W K+N P+ +T +++ V +EG Y A N Sbjct: 1178 SVTLPCNVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQMSVAEEGQYRCVASNI 1237 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G IT+ PP E V G+I L P+P + W ++ Sbjct: 1238 AGNVSKDVRITI-------LVPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDG 1290 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 +S + + D ++++ +T SE +G Y C+ +N AG ++ +T+ V Sbjct: 1291 AQLSIATRNVRILDLGSLQIDVT---SEEHTGTYTCLVTNEAGSTNR--LITLSVIVPPR 1345 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXX 989 + Q Y +G+ +IL C + T +K+ I+ ++ + Sbjct: 1346 IFDGQTQYTVVQGQAIILHCPATGTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGV 1405 Query: 990 XXXDVGVIKCIVKDQETS-----TMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D G KC+V++ S T+ V V I E + + F + L E+ Sbjct: 1406 LPTDFGTYKCVVRNDGGSVYKDITLSVHVAPVIEEAVE--ETFSITIGQTVSLPCEVTGT 1463 Query: 1044 TADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT- 1101 +V W + G I + + L I +T D G Y C+ + VT Sbjct: 1464 PPPIVTWYKSGNPISVTSSMVITQD-----SLDIYSTRPFDTGIYQCVA--SNVAGNVTR 1516 Query: 1102 ----VVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL----VRWFKDGSEIQFSNHI 1152 +V +PP I Q+ + + IEL + D + + W+KDG + N Sbjct: 1517 NFRLIVMIPPSI----QDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDP 1572 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPE-FILVP 1209 +L L+I + D +D+GEY+C V N K + +T+ L P+ + + Sbjct: 1573 RLR-KTAFGTLQIVNVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSPDSYTSLI 1631 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 N + DVTW K + + + I+ +L+I +D YTC Sbjct: 1632 RNPVTLQCLAAGFPPPDVTWLKNGAPLNQEDVRYYIT--PSNSLLIASTMREDSGIYTCN 1689 Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + + +E+ V PP ++ + Y + + V+L + Q++P P W+ + ++ Sbjct: 1690 VSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKDGRV 1749 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGK 1386 I +T + +SL I D+G+Y N G+ + + P PG Sbjct: 1750 I---PYTNSHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINVQVPPYISPGP 1806 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 I ++ + D T+ D + + + + + ++ L Sbjct: 1807 DTITAYLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDEGSLIISDVRELDAG 1866 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE-PNEDIELTCIF 1505 + Y VN+ ++T +K+ +P + L + + N ++ + C Sbjct: 1867 AYY---CLVVNQA----GADTRRITLTVKD----APRIINELPEVMEQIMNTEVRIPCQA 1915 Query: 1506 GGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G P+P+V+W++DG+ ++ + T Y+C A ++ G Sbjct: 1916 TGTPRPQVSWFKDGRPIEQLRGYTVLGDNTLLISSLQPYDNGRYECRAQSESGFDSIDVF 1975 Query: 1565 VGIQQKPVITISN--EDIKQKHKVGDEWLVTA--VIEGIPPPEVIWYKNGNKLENDKEYN 1620 + Q +P I N +D D+ ++ V + PP EV WY+NG + + Sbjct: 1976 IDTQVRPHIAGENTPDDPVVVFTEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIG 2035 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 I + + +R+ L+ + Y EA+N G+S +L+V+ GPVI R + Sbjct: 2036 IHFETGDTSLRLPYLRPEDAGHYHCEATNGQGSSQRHFSLEVH------VGPVI-RNRRQ 2088 Query: 1681 ESVTIE 1686 E VT++ Sbjct: 2089 EQVTVQ 2094 Score = 174 bits (423), Expect = 3e-41 Identities = 238/1080 (22%), Positives = 422/1080 (39%), Gaps = 91/1080 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +++ + V G I + C +P+ I W+F G+ + +N I S+ Sbjct: 2081 PVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMF-GDIAISSQNSRYHIASN----- 2134 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L + V+ G +T +A N G + + + + PP + + ++ SV Sbjct: 2135 GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIV----PPSINDGTSDIVRTLSSSV 2190 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 IL + G P P ITW KN P+ + ++ + +D GVY A N G Sbjct: 2191 ILPCESAGVPFPEITWYKNGAPLNLSNPNLEKLFSGSLRIRSVEEEDSGVYRCVAVNQAG 2250 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-E 871 ++T+ T + +P +R V EK + + ++ +P P W +NN E Sbjct: 2251 --HDYKMLTLWIHTPPSLQPDA--SRNVSTGVDEK--VIIPCNISGSPKPQYRWLKNNRE 2304 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTF 930 ++ + DG L+I +V+S ID G Y C A+N+ G S R+ + V K+T Sbjct: 2305 LLMNYGKMELLEDGS---LMIRDVES-IDRGSYTCEATNAVGVLSRDIRLEVSVAPKITG 2360 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVST---KWYHNKKEISGMDHREIIQEGRXXXXXXX 987 K Y + ++ L+C + KWY + ++G + I++ + Sbjct: 2361 SK-TPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTGQEEAVTIKD-QGITLEIG 2418 Query: 988 XXXXXDVGVIKCIV-KDQETSTM--LVVKETIPEFIRKLQDF--EVKEKDVAILEVEINS 1042 + G C D ++M + + P + ++ V+ D+ +L + Sbjct: 2419 SVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQNIDITLLCEAEGN 2478 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT- 1101 T + WERD + ++ + + Y + G +R ++T D G Y C+ + A Sbjct: 2479 PTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQHT---DSGGYVCVASNNIGYAIKNF 2535 Query: 1102 --VVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDG 1158 VV++PP+ T+ + + T + A + W KD I S +I Sbjct: 2536 HLVVKIPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIPLSTRA-FSISS 2594 Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI---NFTLRLPEFILVPAN 1211 L I D+G YSC EVG +L V+EP I + + + + Sbjct: 2595 NGGSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPIILGELEVNRMQHVQLVEG 2654 Query: 1212 TDAYLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 D +E+P T V W++ ++ E + + D TL+I D Y Sbjct: 2655 DD----IELPCPTTGYPKPRVAWFRDNRILSPPE-YKIKDD---GTLVIPGAMPFDAGVY 2706 Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQ-AFPQPNDEWI 1322 TC ++ + + + V V PP +VD R + + + L + + P + W Sbjct: 2707 TCSAVNEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQ 2766 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + +++ + + S D + L I +V+ + G Y NN G+A +T+ P Sbjct: 2767 KDGISLREDSNIRISRDGQI--LEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPI 2824 Query: 1383 -PPGKP------NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 P G P +I E DS+ + C TI +Y ++V N Sbjct: 2825 FPDGNPVNPMMMSINEDDSTQLG-C--HASGYPPPTIRWYKDGRLVTHNEPGVAVSN--- 2878 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 S + L+ N R A V S ++ Y + + + E P N++ Sbjct: 2879 ---SGEVLRINRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFP-HNVSVVN 2934 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 N IEL C +P P++ WY+DG +L ++ + Y+C+A Sbjct: 2935 NMGIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPDGTTLRIPNAQLHDEGVYQCVA 2994 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N GE + I PVI +S E + G + G+P P V W KN Sbjct: 2995 TNVAGEEMKLFNLQIDVPPVI-VSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNAF 3053 Query: 1613 LENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 + Y+I + ++ I + + + SN+AG + + L+V +P+ G Sbjct: 3054 ISPASIRYDI---DPAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPG 3110 Score = 161 bits (390), Expect = 3e-37 Identities = 240/1096 (21%), Positives = 420/1096 (38%), Gaps = 102/1096 (9%) Query: 633 PPTFSKKPKAQYVDEGSD--ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 PP+ + ++ V G D +++ C + P+P WL E++ + +E Sbjct: 2263 PPSL-QPDASRNVSTGVDEKVIIPCNISGSPKPQYRWLKNNRELLMNYGKMELLEDGS-- 2319 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L I +V+ G+YT A N G S I L++ K P++ V Q + Sbjct: 2320 ----LMIRDVESIDRGSYTCEATNAVGVLSRDIRLEVSVAPKITGSKT-PVEYP-VGQYD 2373 Query: 751 SVILSAQVVGN-PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTL 805 S+ L V P P I W K ++ + +A+ K G T I + + + G Y Sbjct: 2374 SIELQCMVTDAFPPPIIKWYKGDETLTGQEEAVTIKDQGITLEIGSVN---IANAGEYYC 2430 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A N G+A + I V+ P + + + +T + I L+ NP P+IT Sbjct: 2431 TATNDAGMASMNWTIDVQ------VTPSILNGQDEYLTTVQNIDITLLCEAEGNPTPTIT 2484 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W R+N+ + ++ GE+ L IT DSG Y CVASN+ G + + + + Sbjct: 2485 WERDNKPLELRDS--HYLIGEDGSLRIT-APQHTDSGGYVCVASNNIGYAIKNFHLVVKI 2541 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXX 983 T + Q+ ++V L CQ + + W + I + R Sbjct: 2542 PPKTSTQ--QEVVTIGLRQSVTLRCQAAGFPAPTISWRKDNLPIP-LSTRAFSISSNGGS 2598 Query: 984 XXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKE-KDVAILE--- 1037 D G+ CI ++ E S +++K P I L + EV + V ++E Sbjct: 2599 LTINSTREGDSGIYSCIASNEVGEQSLDILLKVQEPPII--LGELEVNRMQHVQLVEGDD 2656 Query: 1038 VEINSETAD-----VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 +E+ T V W RD I+ P + Y + G L I D G Y+C Sbjct: 2657 IELPCPTTGYPKPRVAWFRDNRILSPPE--YKIKDDG---TLVIPGAMPFDAGVYTCSAV 2711 Query: 1093 DESCTAEVTV---VELPPEIITRLQNQKV----NKGNKATFEIELTKGDALVRWFKDGSE 1145 +E+ + +++ V +PP ++ + + N + EI+++ A + W KDG Sbjct: 2712 NEAGNSSISINVTVMVPPLLVDAYRPVDIIVILNNPARLYCEIDISIPMASIVWQKDGIS 2771 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLR 1201 ++ ++I+++ DG Q L+I +++ G Y+C N+ A LTV P I Sbjct: 2772 LREDSNIRISRDG--QILEINQVQVNNEGRYTCIATNNAGNATKFFGLTVHVPPIFPDGN 2829 Query: 1202 LPEFILVPANTDAYLTVEI-----PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256 +++ N D + P T + WYK ++ E +S+ L I Sbjct: 2830 PVNPMMMSINEDDSTQLGCHASGYPPPT--IRWYKDGRLVTHNEPGVAVSN-SGEVLRIN 2886 Query: 1257 KCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQA 1313 + ++TCV + +K V V P+I ++ + + L A Sbjct: 2887 RVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVSVVNNMGIELRCPTVA 2946 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P W + + + + I +L I + D G+Y+ N G Sbjct: 2947 IPVPEIVWYKDGHRLHPFQ-SGVLISPDGTTLRIPNAQLHDEGVYQCVATNVAGEEMKLF 3005 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433 N+ I D P P I+ + + I + G ST I T W Sbjct: 3006 NLQI-DVP-----PVIVSREPNQIAVI------AGGSTTIDCESYGVPKPTVTWTKNNAF 3053 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKN 1490 + ++ V + + + + V + +Q PT+ Sbjct: 3054 ISPASIRYDIDPAGLLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITPGRGR 3113 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYK 1549 +TT+ + + L C GVP P++ W +DG+++ + + Y Sbjct: 3114 VTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDGMLQINDAQPSDAGRYD 3173 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 CIA N G ++ + + P I + + + + E + + GIP P + W N Sbjct: 3174 CIAKNGAGADVFKVILEVHEPPQIAETTKTYEIRVDASVE--LECRVGGIPKPNIRWLFN 3231 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 G +L + K ++I ++ S YT A N AG + E L V D P P Sbjct: 3232 GRELGAQ-----SLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILVVLDVPRLP 3286 Query: 1670 EGPVIMREISRESVTI 1685 P RE S ++++ Sbjct: 3287 RPP---REQSEMTISV 3299 Score = 159 bits (385), Expect = 1e-36 Identities = 228/1071 (21%), Positives = 415/1071 (38%), Gaps = 91/1071 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+ V G I+L C IP P++ W G + +S+A + + Sbjct: 1251 VPPSIEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQ------LSIATRNVRILD 1304 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I + GTYT + N G + I L + PP++ + V QG++ Sbjct: 1305 LGSLQIDVTSEEHTGTYTCLVTNEAGSTNRLITLSVIV----PPRIFDGQTQYTVVQGQA 1360 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810 +IL G P PTITW K + D D + T+ + D G Y N Sbjct: 1361 IILHCPATGTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGVLPTDFGTYKCVVRND 1420 Query: 811 EGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G ++V P E A F IT+ + T+ L VT P P +TWY++ Sbjct: 1421 GGSVYKDITLSVHVAPVIEEAVEETF-----SITIGQ--TVSLPCEVTGTPPPIVTWYKS 1473 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 IS + ++ D ++++ T D+G Y+CVASN AG + R+ + + Sbjct: 1474 GNPISVTSSMVITQD--SLDIYSTR---PFDTGIYQCVASNVAGNVTRNFRLIVMIP--P 1526 Query: 930 FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 ++ + TE G + LEC+ WY + + + G + +++ Sbjct: 1527 SIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPL-GTYNDPRLRKTAFGTLQIV 1585 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILE-VEINSE 1043 D G C V + V T+ P + + ++ L+ + Sbjct: 1586 NVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSPDSYTSLIRNPVTLQCLAAGFP 1645 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAE 1099 DV W ++G + + +Y L I +T D G Y+C + + + E Sbjct: 1646 PPDVTWLKNGAPLNQEDVRYYITPS---NSLLIASTMREDSGIYTCNVSNTAGHQYKHME 1702 Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSN-HIQLTID 1157 +TV P I + + V N + E+ + + W KDG I ++N H ++ Sbjct: 1703 LTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSYPPPTITWLKDGRVIPYTNSHYRI--- 1759 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL 1216 + L I + D+G Y+C N I+ + +++P +I P AYL Sbjct: 1760 -QPSSLDIPMAVVRDSGVYTCIATN-----IVGNISRNYQINVQVPPYISPGPDTITAYL 1813 Query: 1217 --TVEIPDETLDV-----TWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 V +P +++ V W K + D +F + + +LII E D Y C Sbjct: 1814 GQNVTLPCDSIGVPTPMTMWDKSGLQLNYDDSRFHKLDE---GSLIISDVRELDAGAYYC 1870 Query: 1269 VLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSK 1326 ++++ A + T+ V+ P+I++ E + ++V + P+P W + + Sbjct: 1871 LVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVRIPCQATGTPRPQVSWFKDGR 1930 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP----- 1381 I++ + D+ +L I ++ D G Y+ R ++ G +++ + +P Sbjct: 1931 PIEQLRGYTVLGDN---TLLISSLQPYDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGE 1987 Query: 1382 SPPGKPNIL--EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT-KTQT 1438 + P P ++ E D + I C + ++ + + +Y Q I I + T T Sbjct: 1988 NTPDDPVVVFTEEDQTVILEC-NVTDSHPPAEVTWY-QNGQAILARADIGIHFETGDTSL 2045 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + L+ + + A N + ++ + E + + + +T + Sbjct: 2046 RLPYLRPEDAGHYHCEATN-----GQGSSQRHFSL--EVHVGPVIRNRRQEQVTVQVGHS 2098 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556 I + C GVP ++ W + + + Y + + CIA N Sbjct: 2099 ITIHCEASGVPDARILWMFGDIAISSQNSRYHIASNGSLHLREVQVIDSGVFTCIAKNSA 2158 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + + P I DI + + ++ G+P PE+ WYKNG L N Sbjct: 2159 GNDTRVVNINVIVPPSINDGTSDIVR--TLSSSVILPCESAGVPFPEITWYKNGAPL-NL 2215 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 N+ K + +RI+ ++ S Y A N AG +TL ++ PS Sbjct: 2216 SNPNL-EKLFSGSLRIRSVEEEDSGVYRCVAVNQAGHDYKMLTLWIHTPPS 2265 Score = 159 bits (385), Expect = 1e-36 Identities = 266/1181 (22%), Positives = 448/1181 (37%), Gaps = 123/1181 (10%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA-TLVIREVFPEDAGTFT 582 G + C G P P ITW ++ I P D +YD D +A TL + V P D GT+ Sbjct: 1358 GQAIILHCPATGTPPPTITWSKEGIAI-PLND--PHYDVDEIAGTLTMFGVLPTDFGTYK 1414 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 CV +N G + + LS H + + I E + TFS Sbjct: 1415 CVVRNDGG------SVYKDITLSVHVAPV----------------IEEAVEETFS----- 1447 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 + G + L C + P P + W G I ++ S M + L I + + Sbjct: 1448 --ITIGQTVSLPCEVTGTPPPIVTWYKSGNPI--------SVTSSMVITQDSLDIYSTRP 1497 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 F G Y VA N G + L + PP + + + G + L + G P Sbjct: 1498 FDTGIYQCVASNVAGNVTRNFRLIVMI----PPSIQDGPATRTTEVGAHIELECRADGIP 1553 Query: 763 RPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P ITW K+ +P+ P ++ I+ + +D G Y N G A + Sbjct: 1554 LPDITWYKDGEPLGTYNDPRLRKTAFGTLQIVNVDQ-EDSGEYACYVSNDAGKASKFVTL 1612 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 TV P+ ++ T + + L P P +TW +N ++ E + Sbjct: 1613 TVN-------LAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLN-QEDVR 1664 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 N L+I + E DSG Y C SN+AG +T+ + T + SY+ Sbjct: 1665 YYITPSN-SLLIASTMRE-DSGIYTCNVSNTAGHQYKHMELTVYLPP-TSINSGDTSYDV 1721 Query: 941 EEGKTVILECQT-SHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 V L C+ S+ T W + + I + IQ D GV Sbjct: 1722 TLNNPVSLPCEVQSYPPPTITWLKDGRVIPYTNSHYRIQP---SSLDIPMAVVRDSGVYT 1778 Query: 999 CIVKD--QETSTMLVVKETIPEFIRKLQD--FEVKEKDVAILEVEINSETADVVWERDGE 1054 CI + S + +P +I D ++V + I T +W++ G Sbjct: 1779 CIATNIVGNISRNYQINVQVPPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWDKSGL 1838 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIIT 1111 + +++ G L I + D G Y C++ ++ + T +T+ V+ P II Sbjct: 1839 QLNYDDSRFHKLDEG---SLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIIN 1895 Query: 1112 RL---QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 L Q +N + + T V WFKDG I+ + D L I Sbjct: 1896 ELPEVMEQIMNTEVRIPCQATGTPRPQ-VSWFKDGRPIEQLRGYTVLGD---NTLLISSL 1951 Query: 1169 DLDDAGEYSC----EVG-NSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIP 1221 D G Y C E G +S I T P I T P + + L + Sbjct: 1952 QPYDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQTVILECNVT 2011 Query: 1222 DE--TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 D +VTWY+ I + + +L + +D Y C + + +++ Sbjct: 2012 DSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEATNGQGSSQR 2071 Query: 1280 KVEV-VEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 + V P I + +E ++ G +T+ + P W+ I ++++ Sbjct: 2072 HFSLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAISS-QNSRYH 2130 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSS 1396 I S + SL +++V+ D+G++ +N+ G+ +N+ ++ PS G +I+ SSS Sbjct: 2131 IAS-NGSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTSDIVRTLSSS 2189 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 + + E+ G V + EI W KN S NL+ S R +V Sbjct: 2190 VIL---PCESAG--------VPFPEI---TW--YKNGAPLNLSNPNLEKLFSGSLRIRSV 2233 Query: 1457 NEVDIS-----DASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVP 1509 E D ++ YK++ I +P +P +N++T +E + + C G P Sbjct: 2234 EEEDSGVYRCVAVNQAGHDYKML-TLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISGSP 2292 Query: 1510 QPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 +P+ W ++ ++L K Y C A N G + + + Sbjct: 2293 KPQYRWLKNNRELLMNYGKMELLEDGSLMIRDVESIDRGSYTCEATNAVGVLSRDIRLEV 2352 Query: 1568 QQKPVITISNEDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 P IT S ++ D L V + PPP + WYK G++ +E +T K++ Sbjct: 2353 SVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYK-GDETLTGQEEAVTIKDQ 2411 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + I + +++ +Y A+N AG +S+ T+ V PS Sbjct: 2412 GITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPS 2452 Score = 155 bits (376), Expect = 1e-35 Identities = 232/1069 (21%), Positives = 399/1069 (37%), Gaps = 93/1069 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P TF + Y G D +L C + ++ + W+ +G + D I + Sbjct: 528 PTTFMPRRTPGYY--GMDAVLTCDVESMIPFTVRWMRRGTPL--DGPIEFSETGS----- 578 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + I N EG Y+ +A N EG A L I EPP VI + V G Sbjct: 579 ATWTIKNSDSRIEGVYSCIAENEEGSARSETYLDIT----EPPPVIARPYNTSVLPGSDG 634 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 ++S + ITW K N V + + +++ D G Y +A N Sbjct: 635 VMSCFISSTVEYNITWDKPNTLVSLQGHNRVSLMNNGSLVIQDVHPGDAGSYRCRAWNEG 694 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G+ E + V+E + IN +Q +T I L P P + W ++ Sbjct: 695 GVTEEHVYLYVQERPQ--------INAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDG 746 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + + P T+ GE I + N E D G Y C+ASN+AG S V + + Sbjct: 747 QEL-PIVPGTRR--GEIIHQIF-NASRE-DQGIYTCLASNTAG--SDLLNVYVSYHEPPR 799 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXX 988 ++ Q Y T + L C TS + W+ ++++ + + I G Sbjct: 800 IQMTQYRYLTPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNG---DLDIMG 856 Query: 989 XXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSET 1044 D G C ++ + T+ + + P ++ D V +V++ + + Sbjct: 857 VQDSDSGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPP 916 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEV 1100 V W + G+ + + G+ L+IR+ V D G Y C+ +E +A++ Sbjct: 917 PAVTWRKVGQSHLDINPRITMTEDGN---LFIRDMQVEDSGTYVCVAHNEHGSTEASAQL 973 Query: 1101 TVVEL-PPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEI--QFSNHIQLT 1155 + L P+I Q + V + + G+ V WF + ++S ++L Sbjct: 974 RITNLIQPQISATSQEEVVVVEDDVVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELF 1033 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210 DG L I + DAG Y+C +GN +K T I PSI+ T + ++ Sbjct: 1034 PDG---SLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGT--ETSYTVIHH 1088 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 + L + W K I + + + L + TE D Y C + Sbjct: 1089 ESVTLLCPAAGHPPPLIEWIKNGQTIPNL-------GLHQSALTLSYVTEQDAGTYICRV 1141 Query: 1271 LDAKSTTKLKVEV-VEFPP--KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 + +++++ + + PP + V+ + +G VTL + + P P W ++ Sbjct: 1142 SNLAGFSEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLP 1201 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGK 1386 + + + + L I+++ + G Y+ N G+ ++ +TIL PS PG Sbjct: 1202 LPEA--GRNFYVNTDGGLVIQQMSVAEEGQYRCVASNIAGNVSKDVRITILVPPSIEPGN 1259 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 + SI I E +++ Q T + + ++ Q + + + Sbjct: 1260 TEYAVVAGGSI-ILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILDLGSLQIDVTSEEHT 1318 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 +Y NE A T ++I + I P + T + I L C Sbjct: 1319 GTY--TCLVTNE-----AGSTN---RLITLSVIVPPRIFDGQTQYTVVQGQAIILHCPAT 1368 Query: 1507 GVPQPKVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 G P P +TW ++G + Y E YKC+ ND G V Sbjct: 1369 GTPPPTITWSKEGIAIPLNDPHYDVDEIAGTLTMFGVLPTDFGTYKCVVRNDGGSVYKDI 1428 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + + PVI + E+ +G + + G PPP V WYK+GN + IT Sbjct: 1429 TLSVHVAPVIEEAVEE-TFSITIGQTVSLPCEVTGTPPPIVTWYKSGNPISVTSSMVITQ 1487 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + I + + Y ASN AG + L V PS +GP Sbjct: 1488 DS----LDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIPPSIQDGP 1532 Score = 153 bits (371), Expect = 5e-35 Identities = 243/1163 (20%), Positives = 426/1163 (36%), Gaps = 106/1163 (9%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +V CQ G+P P I+W + I S + + N +L I D+G ++C+A Sbjct: 2559 SVTLRCQAAGFPAPTISWRKDNLPIPLST--RAFSISSNGGSLTINSTREGDSGIYSCIA 2616 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 N G S L V+ P G E+ V ++ Q V Sbjct: 2617 SNEVGEQSLDILLKVQEPPIILG-ELEV-----------------------NRMQHVQLV 2652 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + G DI L C P+P +AW + P E I+ D L I F Sbjct: 2653 E-GDDIELPCPTTGYPKPRVAWFRDNRILSPPE---YKIKDD-----GTLVIPGAMPFDA 2703 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILSAQVVGNP 762 G YT AVN G +S+ I + + PP +++ P+ +++ + + + P Sbjct: 2704 GVYTCSAVNEAGNSSISINVTVMV----PPLLVDAYRPVDIIVILNNPARLYCEIDISIP 2759 Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +I W K+ ++ I + +V +EG YT A N+ G A +TV Sbjct: 2760 MASIVWQKDGISLREDSNIRISRDGQILEINQVQVNNEGRYTCIATNNAGNATKFFGLTV 2819 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQ 881 P P +N +++ E + +L + P P+I WY++ +++ +E + Sbjct: 2820 HVPPIFPDGNP--VNPMM-MSINEDDSTQLGCHASGYPPPTIRWYKDGRLVTHNEPGVAV 2876 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + GE + + N + I +G + CVAS+ G S + + V + Sbjct: 2877 SNSGEVLRI---NRVNRIHAGQFTCVASSIVGNISKSYVLNVRVRPEIEGAEFPHNVSVV 2933 Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 + L C T WY + + +I D GV +C Sbjct: 2934 NNMGIELRCPTVAIPVPEIVWYKDGHRLHPFQSGVLISPD-GTTLRIPNAQLHDEGVYQC 2992 Query: 1000 IVKD--QETSTMLVVKETIPEFI--RKLQDFEVKEKDVAILEVE-INSETADVVWERDGE 1054 + + E + ++ +P I R+ V ++ E V W ++ Sbjct: 2993 VATNVAGEEMKLFNLQIDVPPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWTKNNA 3052 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIIT 1111 I P +YD + G L+I +V DEG + C + + + T + + V++ P I Sbjct: 3053 FISPASIRYDIDPAG---LLHIATVTVADEGVFECFVSNSAGNVTRRIDLQVQVQPTITP 3109 Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 G + T + W KDG + + DG L+I D Sbjct: 3110 GRGRVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDG---MLQINDAQP 3166 Query: 1171 DDAGEYSCEVGNSKCTAILTV-----EEPSINFTLRLPEFILVPANTDAYLTV-EIPDET 1224 DAG Y C N + V E P I T + E I V A+ + V IP Sbjct: 3167 SDAGRYDCIAKNGAGADVFKVILEVHEPPQIAETTKTYE-IRVDASVELECRVGGIPKP- 3224 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEV 1283 ++ W + E + L I +D YTC+ DA ++ V Sbjct: 3225 -NIRW-----LFNGRELGAQSLKLANGNLKIPVVRAEDSGAYTCLAQNDAGFAQAERILV 3278 Query: 1284 V-EFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V + P P+ + E I L +P P W + +++ + Sbjct: 3279 VLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAGRITM---T 3335 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 ++ L I +V+ +D+G Y N+ G + +T+ P+ PN +E+ + + Sbjct: 3336 ENHELIIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVELAAGNRLEL 3395 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 E I + V + I +++ +I N++ + S + A N + Sbjct: 3396 ICEAIGVPMPDIAWLVNGTEMIPNPPTFDGRSV----LAIGNVQKSDSGTYMCRAENILG 3451 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + A T +V P + + + T E L C G P+P+VTW ++ + Sbjct: 3452 VRTAI-TAVRVRV-------PPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKNNR 3503 Query: 1521 KLKTAKATYENRXXXXXXX-XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 + ++ YKC A N +G E S + IQ +P+ + ++ Sbjct: 3504 PVALTDTMQQSSDGSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRPMFVVEPQN 3563 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 H G+ L+ + +G P P + W K G ++ I + ++I + + Sbjct: 3564 TTVSH--GENVLLDCIAQGEPEPSMRWQKEGFRVLPVGRVAIL---PNNTLKIVAAQLTD 3618 Query: 1640 SSKYTIEASNTAGTSSVEVTLKV 1662 S Y A N G + + + L V Sbjct: 3619 SGAYMCLAENQMGRAVMTIHLTV 3641 Score = 150 bits (364), Expect = 4e-34 Identities = 230/1120 (20%), Positives = 423/1120 (37%), Gaps = 100/1120 (8%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGS 649 + + + L++ + + + T ++ +PPT Y V + Sbjct: 1666 YITPSNSLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNN 1725 Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 + L C + + P P I WL G ++P N I+ S L I G YT Sbjct: 1726 PVSLPCEVQSYPPPTITWLKDGR-VIPYTNSHYRIQP------SSLDIPMAVVRDSGVYT 1778 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 +A N G S + ++ PP + ++ G++V L +G P P W Sbjct: 1779 CIATNIVGNISRNYQINVQV----PPYISPGPDTITAYLGQNVTLPCDSIGVPTPMTMWD 1834 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 K+ + ++ I+ + D G Y N G +TV++ Sbjct: 1835 KSGLQLNYDDSRFHKLDEGSLIISDVRELDAGAYYCLVVNQAGADTRRITLTVKDA---- 1890 Query: 830 AEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888 P IN E+ + T +++ + T P P ++W+++ I T G+N Sbjct: 1891 ---PRIINELPEVMEQIMNTEVRIPCQATGTPRPQVSWFKDGRPIEQLRGYTVL--GDNT 1945 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS---YETEEGKT 945 L+I+++ D+G Y+C A + +G S + V ++ TEE +T Sbjct: 1946 -LLISSLQP-YDNGRYECRAQSESGFDSIDVFIDTQVRPHIAGENTPDDPVVVFTEEDQT 2003 Query: 946 VILECQT--SH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 VILEC SH WY N + I I E D G C Sbjct: 2004 VILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTSLRLPYLRPEDAGHYHCEAT 2063 Query: 1003 DQETSTM--LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWERDGEIIK 1057 + + S+ ++ + IR + +V + + + + A ++W I Sbjct: 2064 NGQGSSQRHFSLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAIS 2123 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQ 1114 + ++Y G L++R V D G ++CI ++ + T V + V +PP I Sbjct: 2124 SQNSRYHIASNG---SLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPSINDGTS 2180 Query: 1115 NQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLD 1171 + + E + G + W+K+G+ + SN +++ G L+I + + Sbjct: 2181 DIVRTLSSSVILPCE-SAGVPFPEITWYKNGAPLNLSNPNLEKLFSG---SLRIRSVEEE 2236 Query: 1172 DAGEYSC----EVGNSKCTAILTVEEP-------SINFTLRLPEFILVPANTDAYLTVEI 1220 D+G Y C + G+ L + P S N + + E +++P N Sbjct: 2237 DSGVYRCVAVNQAGHDYKMLTLWIHTPPSLQPDASRNVSTGVDEKVIIPCNISG------ 2290 Query: 1221 PDETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 W K + ++ + K L+ D +L+IR D+ YTC +A Sbjct: 2291 -SPKPQYRWLKNNRELLMNYGKMELLED---GSLMIRDVESIDRGSYTCEATNAVGVLSR 2346 Query: 1280 KVEV-VEFPPKIVDYER--EYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 + + V PKI + EY + + + L + AFP P +W + + + Sbjct: 2347 DIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKGDETLTG-QEEA 2405 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNIL-EID 1393 +I + +L I V +AG Y N+ G A + + + PS G+ L + Sbjct: 2406 VTIKDQGITLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQVTPSILNGQDEYLTTVQ 2465 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQ-EIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 + I + E E TI + E+ + ++ ++ + T+ Q+ S + Sbjct: 2466 NIDITLLC-EAEGNPTPTITWERDNKPLELRDSHYLIGEDGSLRITAPQH---TDSGGYV 2521 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A N + + ++ V+K P + +T + + L C G P P Sbjct: 2522 CVASNNIGYA----IKNFHLVVK----IPPKTSTQQEVVTIGLRQSVTLRCQAAGFPAPT 2573 Query: 1513 VTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 ++W +D + + + N Y CIA N+ GE ++ +Q+ Sbjct: 2574 ISWRKDNLPIPLSTRAFSISSNGGSLTINSTREGDSGIYSCIASNEVGEQSLDILLKVQE 2633 Query: 1570 KPVITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 P+I E + +H GD+ + G P P V W+++ N++ + EY I K+ Sbjct: 2634 PPIILGELEVNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRD-NRILSPPEYKI--KDD 2690 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +++ I + YT A N AG SS+ + + V P Sbjct: 2691 GTLV-IPGAMPFDAGVYTCSAVNEAGNSSISINVTVMVPP 2729 Score = 149 bits (361), Expect = 8e-34 Identities = 176/747 (23%), Positives = 296/747 (39%), Gaps = 61/747 (8%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 I L C VAIP P+I W G + P ++ V I D + L+I N + EG Y Sbjct: 2938 IELRCPTVAIPVPEIVWYKDGHRLHPFQS-GVLISPDG----TTLRIPNAQLHDEGVYQC 2992 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWC 769 VA N GE L+I PP ++ + I V G S + + G P+PT+TW Sbjct: 2993 VATNVAGEEMKLFNLQIDV----PPVIVSREPNQIAVIAGGSTTIDCESYGVPKPTVTWT 3048 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 KNN + + D D + + V DEGV+ NS G +T + Sbjct: 3049 KNNAFISPASIRYDIDPAGLLHIATVTVADEGVFECFVSNSAG------NVTRRIDLQVQ 3102 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 +P + R +T + +++L T P P I W ++ + +SP E DG Sbjct: 3103 VQPTITPGR-GRVTTQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISDG---- 3157 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 ++ N D+G Y C+A N AG +V ++V + + K+YE +V LE Sbjct: 3158 MLQINDAQPSDAGRYDCIAKNGAGADVF--KVILEVHEPPQIAETTKTYEIRVDASVELE 3215 Query: 950 CQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--- 1004 C+ + +W N +E+ + + G D G C+ ++ Sbjct: 3216 CRVGGIPKPNIRWLFNGRELGAQSLK--LANGN---LKIPVVRAEDSGAYTCLAQNDAGF 3270 Query: 1005 -ETSTMLVVKET--IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKK 1060 + +LVV + +P R+ + + A+L + +V W +DG +++P Sbjct: 3271 AQAERILVVLDVPRLPRPPREQSEMTISVNRRAVLTCPADGYPPPEVTWRKDGILVEPAG 3330 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQK 1117 E +L I D G Y+C+ + + + V++ P + + Sbjct: 3331 RITMTEN----HELIIDRVQESDSGTYTCVATNSIGSNRLNFYLTVQVAPTFTHFPNDVE 3386 Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 + GN+ E G + + W +G+E+ N T DG + L I + D+G Sbjct: 3387 LAAGNRLELICEAI-GVPMPDIAWLVNGTEM-IPN--PPTFDG-RSVLAIGNVQKSDSGT 3441 Query: 1176 YSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-PDETLDVTWYKK 1232 Y C N TAI V R+P + A L + D +VTW K Sbjct: 3442 YMCRAENILGVRTAITAVRVRVPPRIHRIPSDTTLTLGERAVLNCAVNGDPKPEVTWLKN 3501 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV 1291 + T+ SD +LII D Y C L+ ++ + ++ P V Sbjct: 3502 NRPVALTDTMQQSSD---GSLIIAPTAISDAGFYKCQALNLYGLDEVSYHLEIQSRPMFV 3558 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + + G +V L Q P+P+ W + + + +I + +L I + Sbjct: 3559 VEPQNTTVSHGENVLLDCIAQGEPEPSMRW--QKEGFRVLPVGRVAI-LPNNTLKIVAAQ 3615 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL 1378 TD+G Y EN G A + +++T++ Sbjct: 3616 LTDSGAYMCLAENQMGRAVMTIHLTVM 3642 Score = 140 bits (340), Expect = 3e-31 Identities = 237/1079 (21%), Positives = 395/1079 (36%), Gaps = 76/1079 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P + P V+ G ++ + C + P P + W G+ + D N + + D ++ Sbjct: 885 GSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHL-DINPRITMTEDGNL 943 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + I +++ GTY VA N G L+I T +P + ++V + + Sbjct: 944 F-----IRDMQVEDSGTYVCVAHNEHGSTEASAQLRI-TNLIQPQISATSQEEVVVVEDD 997 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V+ + GNP PT+TW +++ + + P S+ I + + D G YT AE Sbjct: 998 VVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPDGSLGI-RGAVMSDAGNYTCVAE 1056 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N+ G I V PP TV ++ L+ +P P I W + Sbjct: 1057 NAIGNDTKITRIRVH-------NPPSISGTETSYTVIHHESVTLLCPAAGHPPPLIEWIK 1109 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N + I P+ + Q+ L ++ V +E D+G Y C SN AG S + I V Sbjct: 1110 NGQTI-PNLGLHQS------ALTLSYV-TEQDAGTYICRVSNLAGFSEIEITLFILVPPA 1161 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 +G +V L C T + K + + Sbjct: 1162 HEGVETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLPLPEAGRNFYVNTDGGLVIQQ 1221 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVE-INSET 1044 + G +C+ + + V+ TI P ++ V IL E Sbjct: 1222 MSVAEEGQYRCVASNIAGNVSKDVRITILVPPSIEPGNTEYAVVAGGSIILSCEAYGIPM 1281 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV 1102 +VVW++DG + G L I TS G Y+C++ +E S +T+ Sbjct: 1282 PEVVWQKDGAQLSIATRNVRILDLG---SLQIDVTSEEHTGTYTCLVTNEAGSTNRLITL 1338 Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 V +PP I V +G T + W K+G I N +D Sbjct: 1339 SVIVPPRIFDGQTQYTVVQGQAIILHCPATGTPPPTITWSKEGIAIPL-NDPHYDVDEIA 1397 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 L ++ D G Y C V N + + S++ + E + + TV + Sbjct: 1398 GTLTMFGVLPTDFGTYKCVVRNDGGSVYKDI-TLSVHVAPVIEEAVEETFSITIGQTVSL 1456 Query: 1221 PDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AK 1274 P E VTWYK + I T + D +L I D Y CV + A Sbjct: 1457 PCEVTGTPPPIVTWYKSGNPISVTSSMVITQD----SLDIYSTRPFDTGIYQCVASNVAG 1512 Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + T+ +V PP I D + G+ + L P P+ W + + + + Sbjct: 1513 NVTRNFRLIVMIPPSIQDGPATRTTEVGAHIELECRADGIPLPDITWYKDGEPLG--TYN 1570 Query: 1335 KPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393 P + + +L I V+ D+G Y + N+ G A + +T+ P P D Sbjct: 1571 DPRLRKTAFGTLQIVNVDQEDSGEYACYVSNDAGKASKFVTLTVNLAPILLDSP-----D 1625 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 S + I T+ + D T W+ Q ++ T S+ A Sbjct: 1626 SYTSLI-------RNPVTLQCLAAGFPPPDVT-WLK-NGAPLNQEDVRYYITPSNSLLIA 1676 Query: 1454 YAVNE---VDISDASETTEY-YKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGV 1508 + E + + S T + YK ++ T PT + + N + L C Sbjct: 1677 STMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPCEVQSY 1736 Query: 1509 PQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 P P +TW +DG+ + + Y Y CIA N G + + + + Sbjct: 1737 PPPTITWLKDGRVIPYTNSHYRIQPSSLDIPMAVVRDSGVYTCIATNIVGNISRNYQINV 1796 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 Q P I+ + I +G + G+P P +W K+G +L D + ++ Sbjct: 1797 QVPPYISPGPDTITA--YLGQNVTLPCDSIGVPTPMTMWDKSGLQLNYD-DSRFHKLDEG 1853 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPVIMREISRESVTI 1685 S+I I +++ + Y N AG + +TL V D P E P +M +I V I Sbjct: 1854 SLI-ISDVRELDAGAYYCLVVNQAGADTRRITLTVKDAPRIINELPEVMEQIMNTEVRI 1911 Score = 133 bits (321), Expect = 6e-29 Identities = 214/966 (22%), Positives = 362/966 (37%), Gaps = 87/966 (9%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 +PP P ++ G +L+ V T+ W + P+ S+ + + TI Sbjct: 526 DPPTTFMPRRTPGY-YGMDAVLTCDVESMIPFTVRWMRRGTPLDGPIEFSETGSATWTI- 583 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K + EGVY+ AEN EG A + + + EP PP+ + + + + Sbjct: 584 KNSDSRIEGVYSCIAENEEGSARSETYLDITEP------PPVIARPYNTSVLPGSDGV-M 636 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 ++ +ITW + N ++S + N LVI +V D+G Y+C A N Sbjct: 637 SCFISSTVEYNITWDKPNTLVSLQGHNRVSL-MNNGSLVIQDVHPG-DAGSYRCRAWNEG 694 Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKE---I 967 G + V + V++ + Q + + + L C + +W + +E + Sbjct: 695 GVTEE--HVYLYVQERPQINAYQGNVTFTSSQNITLRCSANGYPHPELRWLKDGQELPIV 752 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQ- 1024 G EII + D G+ C+ + S +L V + P I+ Q Sbjct: 753 PGTRRGEIIHQ-------IFNASREDQGIYTCLASNTAGSDLLNVYVSYHEPPRIQMTQY 805 Query: 1025 DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 + A L + ++ W + + + + + L I D Sbjct: 806 RYLTPPSQKATLSCPTSGVPPPEITWFKGDRDL----TRVTYTRIWPNGDLDIMGVQDSD 861 Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKG-NKATFEIELTKGDALVRW 1139 G Y+C +E+ TV V P I+ + VN G N + I + V W Sbjct: 862 SGSYTCYATNEAGVVSETVHLEVGSSPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTW 921 Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-- 1192 K G S + + I +T DG L I D ++D+G Y C E G+++ +A L + Sbjct: 922 RKVGQSHLDINPRITMTEDG---NLFIRDMQVEDSGTYVCVAHNEHGSTEASAQLRITNL 978 Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI--EDTEKFTLISDVK 1249 +P I+ T + E ++V + V + VTW+ + E + + L D Sbjct: 979 IQPQISATSQ-EEVVVVEDDVVVRCNVISGNPPPTVTWFHSSERLYPEYSPRLELFPD-- 1035 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 +L IR D YTCV +A + TK+ V PP I E Y + VTLL Sbjct: 1036 -GSLGIRGAVMSDAGNYTCVAENAIGNDTKITRIRVHNPPSISGTETSYTVIHHESVTLL 1094 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 P P EWI N + I P++ ++LT+ V DAG Y R+ N G Sbjct: 1095 CPAAGHPPPLIEWIKNGQTI-------PNLGLHQSALTLSYVTEQDAGTYICRVSNLAGF 1147 Query: 1369 ADVEMNVTILDKPS-----PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 +++E+ + IL P+ G N+ + DS ++ C T I ++ + Sbjct: 1148 SEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLP-C--NVRGTPPPQISWFKDNLPLPE 1204 Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 V T IQ + ++R A N K ++ T + P+ Sbjct: 1205 AGRNFYVN--TDGGLVIQQMSVAEEGQYRCVASNIAG--------NVSKDVRITILVPPS 1254 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXX 1541 +E I L+C G+P P+V W +DG +L A + Sbjct: 1255 IEPGNTEYAVVAGGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILDLGSLQIDVTS 1314 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+ N+ G + + P I + + G ++ G PP Sbjct: 1315 EEHTGTYTCLVTNEAGSTNRLITLSVIVPP--RIFDGQTQYTVVQGQAIILHCPATGTPP 1372 Query: 1602 PEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P + W K G + ND Y++ E + + + + Y N G+ ++TL Sbjct: 1373 PTITWSKEGIAIPLNDPHYDV--DEIAGTLTMFGVLPTDFGTYKCVVRNDGGSVYKDITL 1430 Query: 1661 KVYDKP 1666 V+ P Sbjct: 1431 SVHVAP 1436 Score = 114 bits (274), Expect = 3e-23 Identities = 81/298 (27%), Positives = 131/298 (43%), Gaps = 24/298 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + PTF+ P + G+ + L C + +P PDIAWL G E++P+ Sbjct: 3374 VAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTFDGR------- 3426 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 SVL I NV+K GTY A N G + ++++ PP++ + GE Sbjct: 3427 -SVLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRV----PPRIHRIPSDTTLTLGER 3481 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 +L+ V G+P+P +TW KNN+PV T S+ I+ P + D G Y +A N Sbjct: 3482 AVLNCAVNGDPKPEVTWLKNNRPVALTDTMQQSSDGSL-IIAPTAISDAGFYKCQALNLY 3540 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G+ E S + ++ P+F+ Q TV + L P PS+ W + Sbjct: 3541 GLDEVSYHLEIQ-------SRPMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKEGF 3593 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + P + +++V + DSG Y C+A N G++ +T+ E +T Sbjct: 3594 RVLPVGRVA-ILPNNTLKIVAAQL---TDSGAYMCLAENQMGRAVMTIHLTVMGECLT 3647 Score = 84.2 bits (199), Expect = 4e-14 Identities = 123/568 (21%), Positives = 208/568 (36%), Gaps = 51/568 (8%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 VRW + G+ + I+ + G I + D G YSC E G+++ L + Sbjct: 558 VRWMRRGTPLD--GPIEFSETGSAT-WTIKNSDSRIEGVYSCIAENEEGSARSETYLDIT 614 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKR 1251 EP + P V +D ++ I ++TW K +++ + +S + Sbjct: 615 EPPP--VIARPYNTSVLPGSDGVMSCFISSTVEYNITWDKPNTLVS-LQGHNRVSLMNNG 671 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 +L+I+ D Y C + T+ V + V+ P+I Y+ ++TL Sbjct: 672 SLVIQDVHPGDAGSYRCRAWNEGGVTEEHVYLYVQERPQINAYQGNVTFTSSQNITLRCS 731 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 +P P W+ + + + T+ I D GIY N G Sbjct: 732 ANGYPHPELRWLKDGQELPIVPGTRRG----EIIHQIFNASREDQGIYTCLASNTAGSDL 787 Query: 1371 VEMNVTILDKP----------SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + + V+ + P +PP + L +S + PE T Sbjct: 788 LNVYVSYHEPPRIQMTQYRYLTPPSQKATLSCPTSGV----PPPEITWFKG--------- 834 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 + D T + I ++ + S + YA NE + SET E Sbjct: 835 DRDLTRVTYTRIWPNGDLDIMGVQDSDSGSYTCYATNEAGV--VSETVHL-----EVG-S 886 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXX 1538 SP + +P ++ ++ +TCI G P P VTW + G+ + T Sbjct: 887 SPIILQPPIDLGVNYGMNVSVTCIAMGHPPPAVTWRKVGQSHLDINPRITMTEDGNLFIR 946 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA-VIE 1597 Y C+A N+HG E S + I IS ++ V D+ +V VI Sbjct: 947 DMQVEDSGTYVCVAHNEHGSTEASAQLRITNLIQPQISATSQEEVVVVEDDVVVRCNVIS 1006 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 G PPP V W+ + +L + + S + I+ S + YT A N G + Sbjct: 1007 GNPPPTVTWFHSSERLYPEYSPRLELFPDGS-LGIRGAVMSDAGNYTCVAENAIGNDTKI 1065 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTI 1685 ++V++ PS I ESVT+ Sbjct: 1066 TRIRVHNPPSISGTETSYTVIHHESVTL 1093 Score = 61.7 bits (143), Expect = 2e-07 Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 V +++ +G ++ C GYP+P++ WFR I+ P + Y + TLVI Sbjct: 2643 VNRMQHVQLVEGDDIELPCPTTGYPKPRVAWFRDNRILSPPE-----YKIKDDGTLVIPG 2697 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 P DAG +TC A N AG +S + + V P Sbjct: 2698 AMPFDAGVYTCSAVNEAGNSSISINVTVMVP 2728 Score = 50.8 bits (116), Expect = 4e-04 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 3/131 (2%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 ++API ++ + + V +C G+P P +TW + A + +D + Y N Sbjct: 1615 NLAPILLDSPDSYTSLIRNPVTLQCLAAGFPPPDVTWLKNGAPLN-QEDVRYYITPSN-- 1671 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 +L+I ED+G +TC N AG EL V P + S T Sbjct: 1672 SLLIASTMREDSGIYTCNVSNTAGHQYKHMELTVYLPPTSINSGDTSYDVTLNNPVSLPC 1731 Query: 627 DILEGIPPTFS 637 ++ PPT + Sbjct: 1732 EVQSYPPPTIT 1742 Score = 50.0 bits (114), Expect = 7e-04 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 VE + G +V C V G P PQI+WF+ + P Y + D LVI++ Sbjct: 1165 VETTGVVNVTQGDSVTLPCNVRGTPPPQISWFKDNLPL-PEAGRNFYVNTD--GGLVIQQ 1221 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + + G + CVA N AG S + + P S Sbjct: 1222 MSVAEEGQYRCVASNIAGNVSKDVRITILVPPS 1254 Score = 50.0 bits (114), Expect = 7e-04 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + +C+ G P+P +TW + A I P+ + YD D L I V D G F C Sbjct: 3028 GGSTTIDCESYGVPKPTVTWTKNNAFISPA---SIRYDIDPAGLLHIATVTVADEGVFEC 3084 Query: 584 VAKNAAGFASSTTELIVE 601 N+AG + +L V+ Sbjct: 3085 FVSNSAGNVTRRIDLQVQ 3102 Score = 48.8 bits (111), Expect = 0.002 Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 2/78 (2%) Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 + G P P +TWF + + P ++ D +L IR DAG +TCVA+NA G Sbjct: 1005 ISGNPPPTVTWFHSSERLYPEYSPRLELFPDG--SLGIRGAVMSDAGNYTCVAENAIGND 1062 Query: 593 SSTTELIVEAPLSDHGSE 610 + T + V P S G+E Sbjct: 1063 TKITRIRVHNPPSISGTE 1080 Score = 48.8 bits (111), Expect = 0.002 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 T G +V+ C G P P+I W + + P + F + D L I + P DAG Sbjct: 3116 TQIGQSVRLFCDATGVPTPEILWQKDGQRVSPMEGFLIISD----GMLQINDAQPSDAGR 3171 Query: 581 FTCVAKNAAG 590 + C+AKN AG Sbjct: 3172 YDCIAKNGAG 3181 Score = 47.6 bits (108), Expect = 0.004 Identities = 31/99 (31%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Query: 508 MAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +AP+ E + + G TV C+V G P P +TW++ I + + D Sbjct: 1434 VAPVIEEAVEETFSITIGQTVSLPCEVTGTPPPIVTWYKSGNPISVTSSMVITQD----- 1488 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 +L I P D G + CVA N AG + LIV P S Sbjct: 1489 SLDIYSTRPFDTGIYQCVASNVAGNVTRNFRLIVMIPPS 1527 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 T G+ ++ EC+ +G P P ITW++ + D ++ TL I V ED+G Sbjct: 1537 TEVGAHIELECRADGIPLPDITWYKDGEPLGTYNDPRL--RKTAFGTLQIVNVDQEDSGE 1594 Query: 581 FTCVAKNAAGFASSTTELIVE-APL 604 + C N AG AS L V AP+ Sbjct: 1595 YACYVSNDAGKASKFVTLTVNLAPI 1619 Score = 46.0 bits (104), Expect = 0.011 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 6/76 (7%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 ++V+ EC+V G P+P I W + +Q ++ + N+ V+R ED+G +TC+ Sbjct: 3210 ASVELECRVGGIPKPNIRWLFNGRELG-AQSLKLA--NGNLKIPVVRA---EDSGAYTCL 3263 Query: 585 AKNAAGFASSTTELIV 600 A+N AGFA + L+V Sbjct: 3264 AQNDAGFAQAERILVV 3279 Score = 45.6 bits (103), Expect = 0.015 Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 6/105 (5%) Query: 503 SEEQSMAPIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY 560 S E + P+ + + + T G ++ C+ G P +I W F AI S Y+ Sbjct: 2074 SLEVHVGPVIRNRRQEQVTVQVGHSITIHCEASGVPDARILWMFGDIAI---SSQNSRYH 2130 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 N +L +REV D+G FTC+AKN+AG + + V P S Sbjct: 2131 IASN-GSLHLREVQVIDSGVFTCIAKNSAGNDTRVVNINVIVPPS 2174 Score = 44.8 bits (101), Expect = 0.026 Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 TP C G P P+ITWF+ + +++ + D L I V D+G+ Sbjct: 809 TPPSQKATLSCPTSGVPPPEITWFKGDRDLTRVTYTRIWPNGD----LDIMGVQDSDSGS 864 Query: 581 FTCVAKNAAGFASSTTELIV 600 +TC A N AG S T L V Sbjct: 865 YTCYATNEAGVVSETVHLEV 884 Score = 43.6 bits (98), Expect = 0.061 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+ EG P P ITW R KP + +Y +L I D+G + CVA N G Sbjct: 2473 CEAEGNPTPTITWERDN---KPLELRDSHYLIGEDGSLRITAPQHTDSGGYVCVASNNIG 2529 Query: 591 FASSTTELIVEAP 603 +A L+V+ P Sbjct: 2530 YAIKNFHLVVKIP 2542 Score = 41.1 bits (92), Expect = 0.33 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 521 TPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 T + TV EC V + +P ++TW++ I D ++++ + + L + + PEDAG Sbjct: 1998 TEEDQTVILECNVTDSHPPAEVTWYQNGQAILARADIGIHFETGDTS-LRLPYLRPEDAG 2056 Query: 580 TFTCVAKNAAG 590 + C A N G Sbjct: 2057 HYHCEATNGQG 2067 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 5/115 (4%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS--TVQFECQV-EGYPRPQITWFRQ 546 E + + V + E S+AP P P G +++ +C V + +P P I W++ Sbjct: 2336 EATNAVGVLSRDIRLEVSVAPKITGSKTPVEYPVGQYDSIELQCMVTDAFPPPIIKWYKG 2395 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + Q+ + D + TL I V +AG + C A N AG AS + V+ Sbjct: 2396 DETLT-GQEEAVTIKDQGI-TLEIGSVNIANAGEYYCTATNDAGMASMNWTIDVQ 2448 Score = 40.3 bits (90), Expect = 0.57 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 3/88 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 D ST Q C GYP P I W++ ++ ++ + V L I V AG FT Sbjct: 2841 DDST-QLGCHASGYPPPTIRWYKDGRLVTHNEPGVAVSNSGEV--LRINRVNRIHAGQFT 2897 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSE 610 CVA + G S + L V G+E Sbjct: 2898 CVASSIVGNISKSYVLNVRVRPEIEGAE 2925 Score = 40.3 bits (90), Expect = 0.57 Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 7/101 (6%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVA 566 +AP F G+ ++ C+ G P P I W T +I F D + Sbjct: 3374 VAPTFTHFPNDVELAAGNRLELICEAIGVPMPDIAWLVNGTEMIPNPPTF------DGRS 3427 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 L I V D+GT+ C A+N G ++ T + V P H Sbjct: 3428 VLAIGNVQKSDSGTYMCRAENILGVRTAITAVRVRVPPRIH 3468 Score = 39.9 bits (89), Expect = 0.75 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V C G+P P +TW + + + D L IR++ ED+GT+ C Sbjct: 902 GMNVSVTCIAMGHPPPAVTWRK---VGQSHLDINPRITMTEDGNLFIRDMQVEDSGTYVC 958 Query: 584 VAKNAAGFASSTTEL 598 VA N G ++ +L Sbjct: 959 VAHNEHGSTEASAQL 973 Score = 39.5 bits (88), Expect = 0.99 Identities = 28/109 (25%), Positives = 40/109 (36%), Gaps = 8/109 (7%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +V C G+P P I W + I P+ + L + V +DAGT+ C Sbjct: 1090 SVTLLCPAAGHPPPLIEWIKNGQTI-PNLGLHQ-------SALTLSYVTEQDAGTYICRV 1141 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP 634 N AGF+ L + P + G E T + G PP Sbjct: 1142 SNLAGFSEIEITLFILVPPAHEGVETTGVVNVTQGDSVTLPCNVRGTPP 1190 Score = 37.5 bits (83), Expect = 4.0 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ C+ G P P++ W + A + + D + +L I E GT+TC Sbjct: 1267 GGSIILSCEAYGIPMPEVVWQKDGAQLSIATRNVRILD---LGSLQIDVTSEEHTGTYTC 1323 Query: 584 VAKNAAGFASS--TTELIVEAPLSDHGSEMTV 613 + N AG + T +IV + D ++ TV Sbjct: 1324 LVTNEAGSTNRLITLSVIVPPRIFDGQTQYTV 1355 Score = 37.5 bits (83), Expect = 4.0 Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G C V G P+P++TW + + + Q D +L+I DAG + C Sbjct: 3479 GERAVLNCAVNGDPKPEVTWLKNNRPVALTDTMQQSSD----GSLIIAPTAISDAGFYKC 3534 Query: 584 VAKNAAGFASSTTELIVEA 602 A N G + L +++ Sbjct: 3535 QALNLYGLDEVSYHLEIQS 3553 Score = 37.1 bits (82), Expect = 5.3 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 4/91 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+FV + + G V +C +G P P + W ++ + P + +N +V Sbjct: 3555 PMFVVEPQNTTVSHGENVLLDCIAQGEPEPSMRWQKEGFRVLPVGRVAIL--PNNTLKIV 3612 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ++ D+G + C+A+N G A T L V Sbjct: 3613 AAQL--TDSGAYMCLAENQMGRAVMTIHLTV 3641 >UniRef50_O76518 Cluster: Hemicentin precursor; n=4; Eukaryota|Rep: Hemicentin precursor - Caenorhabditis elegans Length = 5198 Score = 213 bits (520), Expect = 4e-53 Identities = 282/1187 (23%), Positives = 464/1187 (39%), Gaps = 142/1187 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC +E ITW RQ K Q + + L I + PEDA +++C Sbjct: 2957 GDPLTLECPIEDTSGVHITWSRQFG--KDGQLDMRAQSSSDKSKLYIMQATPEDADSYSC 3014 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A N AG A + ++ V P G + EGIPP Sbjct: 3015 IAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCR-TEGIPP--------- 3064 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 PE I+W G+ I+ ++ + D+ L+I N+K Sbjct: 3065 -----------------PE--ISWFLDGKPILEMPGVTYK-QGDLS-----LRIDNIKPN 3099 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 QEG YT VA N+ G A ++I EPP+V+ + M V +G + +V GNP Sbjct: 3100 QEGRYTCVAENKAGRAEQDTYVEI----SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPE 3155 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P + W K+ +P + S L+ + D G YT A N G ++T+ + V Sbjct: 3156 PVVNWLKDGEPYTS-DLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV- 3213 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 PP + + + KE T + +VT PVP +TW RN + I + F Sbjct: 3214 ------LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEI-------EQF 3260 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-EKVTFVKHLQKSYETEE 942 N L I N + D G Y C+ASN AG + A IDV K TF H + ++ E Sbjct: 3261 ---NPVLHIRNA-TRADEGKYSCIASNEAGTAV--ADFLIDVFTKPTFETH-ETTFNIVE 3313 Query: 943 GKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G++ +EC+ H T W + + MD+ II R D G+ C+ Sbjct: 3314 GESAKIECKIDGHPKPTISWLKGGRPFN-MDN--IILSPRGDTLMILKAQRFDGGLYTCV 3370 Query: 1001 V------KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE 1054 +Q+ + K I E I + V ++ + + + T V W+R G+ Sbjct: 3371 ATNSYGDSEQDFKVNVYTKPYIDETIDQTPK-AVAGGEIILKCPVLGNPTPTVTWKR-GD 3428 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEIIT 1111 P +++ ++ I + + D G+YSCI +E+ T V P + Sbjct: 3429 DAVPNDSRHTIVNNYDLK---INSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVR 3485 Query: 1112 RLQN-QKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 + N +V + + T + +T + WF+ + + ++ DG + I Sbjct: 3486 KGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDG--SHITINKAK 3543 Query: 1170 LDDAGEYSC----EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD-E 1223 L D G+Y C E G S IL + P I+ + + + + A T YL I Sbjct: 3544 LSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVART-IYLECPISGIP 3602 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281 DV W K I T+ +++ T I DQ YTC + K++ + Sbjct: 3603 QPDVIWTKNGMDINMTDSRVILAQ-NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSL 3661 Query: 1282 EVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDE-----WIVNSKIIKKCKHTK 1335 +V+ PP+ + + IKR G +TL + D+ W +S+ + Sbjct: 3662 DVLS-PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDN 3720 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395 I LTI + +AG+Y N G A +E V IL SPP +++I + Sbjct: 3721 VDISDDGRKLTISQASLENAGLYTCIALNRAGEASLEFKVEIL---SPP----VIDISRN 3773 Query: 1396 SINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-SVKNITKTQT--------SIQNLKT 1445 + +P+ N TI+ V + +W+ + K +T + +Q L+T Sbjct: 3774 DV-----QPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRT 3828 Query: 1446 NSSY--RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 +S + ++ A N+ + + + + + S + P+K + E I L C Sbjct: 3829 DSDHAGKWSCVAENDAGVKELEMVLDVF----TPPVVSVKSDNPIKAL----GETITLFC 3880 Query: 1504 IFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 G P P++ W + G + A+ + + Y C A N G Sbjct: 3881 NASGNPYPQLKWAKGGSLIFDSPDGARISLKG-ARLDIPHLKKTDVGDYTCQALNAAGTS 3939 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 E S V + P I D+ + + + +G P P++ W NG L + Sbjct: 3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTP- 3998 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 IT ++ I+I + S YT A N AG+ ++ + V P Sbjct: 3999 GITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAP 4045 Score = 194 bits (473), Expect = 2e-47 Identities = 268/1073 (24%), Positives = 421/1073 (39%), Gaps = 82/1073 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PTF + EG +EC++ P+P I+WL KG +NI ++ D Sbjct: 3300 PTFETHETTFNIVEGESAKIECKIDGHPKPTISWL-KGGRPFNMDNIILSPRGD------ 3352 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I ++F G YT VA N G++ + + T + + K++ G +I Sbjct: 3353 TLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGEII 3409 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L V+GNP PT+TW + + A+P S H TI+ +K V T A I Sbjct: 3410 LKCPVLGNPTPTVTWKRGD---DAVPNDS---RH--TIVNNYDLKINSVTTEDAGQYSCI 3461 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A A E P F+ + + V E TI + VT P+PSI+W+R ++ Sbjct: 3462 AVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKP 3521 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + + + + DG +I + N D G Y C ASN AG S + I V Sbjct: 3522 VYLYDRYSISPDGSHITI---NKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKS 3578 Query: 933 HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 ++ + +T+ LEC S W N +I+ D R I+ + Sbjct: 3579 NIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNN-ETFGIENVQ 3637 Query: 991 XXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEV------EI 1040 D G C + + + + + PEF I Q +E D L +I Sbjct: 3638 VTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDI 3697 Query: 1041 NSETADVVWERDGEIIK-PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + DV W +D + + D G RKL I S+ + G Y+CI + + A Sbjct: 3698 ADQVMDVSWTKDSRALDGDLTDNVDISDDG--RKLTISQASLENAGLYTCIALNRAGEAS 3755 Query: 1100 VTV-VEL--PPEI-ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQ 1153 + VE+ PP I I+R Q N+ T G ++W K+G E+ +I+ Sbjct: 3756 LEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIR 3815 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 + G Q L+I D D AG++SC + G + +L V P + +++ I Sbjct: 3816 IVEQG--QVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPV-VSVKSDNPIKAL 3872 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 T + + W K S+I D+ IS +K L I + D +YTC Sbjct: 3873 GETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQ 3931 Query: 1270 LLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 L+A T++ V V V PP+I + R+ +TL Q P P W +N Sbjct: 3932 ALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGT 3991 Query: 1327 IIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--S 1382 + H+ P I S S + I V +D G+Y EN G ++ NV ++ P S Sbjct: 3992 AL---THSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS 4048 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQ 1441 G ++E + + I C E + ++ ++T V+ +T +I Sbjct: 4049 NGGTKQVIEGELAVIE-CLVEGYPAPQ---VSWLRNGNRVETGVQ-GVRYVTDGRMLTII 4103 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 ++ S + A NE + + T E V+ KI + T +T L Sbjct: 4104 EARSLDSGIYLCSATNEAGSAQQAYTLE---VLVSPKIITSTPGV----LTPSSGSKFSL 4156 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 C G P P ++W +G +K + + Y+C A ND G Sbjct: 4157 PCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGADT 4216 Query: 1561 TSCVVGIQQKPVITIS-NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 V P I+ S N I G E ++ IE E W KNG L Sbjct: 4217 LEFPVQTIVAPKISTSGNRYINGSE--GTETVIKCEIES-ESSEFSWSKNGVPLLPSN-- 4271 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 N+ E +I+I + S +Y+ A+N AG ++ + L V P E P Sbjct: 4272 NLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERP 4324 Score = 187 bits (456), Expect = 3e-45 Identities = 248/1061 (23%), Positives = 417/1061 (39%), Gaps = 91/1061 (8%) Query: 648 GSDILLECRLVAIPEPD--IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 G DI L C L + W G E D +V I SD H L IT+ K Sbjct: 1657 GKDISLSCDLQTESDDKTTFVWSINGSE--SDRPDNVQIPSDGHR----LYITDAKPENN 1710 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVILSAQVVGNPR 763 G Y N G+A + L + EPP +EP+ + + +IL QV GNP+ Sbjct: 1711 GKYMCRVTNSAGKAERTLTLDVL----EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPK 1766 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY-TLKAENSEGIAETSAVITV 822 PT+ W + V KS S+++L+ +K+ + + AEN G A I Sbjct: 1767 PTVIWKIDGNDVD----KSWLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRDFFI-- 1820 Query: 823 EEPTEENAEPPLFINRFQEITV-KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 +N P F N + T+ +E TI L V+ ITW + ++ ++ I Sbjct: 1821 -----QNIAAPTFKNEGDQETIFRESETITLDCPVSLGDF-QITWMKQGLPLTENDAI-- 1872 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 F +N L I N + + + Y CVA+N+AG+ S V + V + +K+ + E Sbjct: 1873 -FTLDNTRLTILNANRDHED-IYTCVANNTAGQVSKDFDVVVQV--LPKIKNAVVTLEIN 1928 Query: 942 EGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 EG+ +IL C + T + KW N+ ++ +E + GV KC Sbjct: 1929 EGEEIILTCDAEGNPTPTAKWDFNQGDLP----KEAVFVNNNHTVVVNNVTKYHTGVYKC 1984 Query: 1000 IVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWERDG 1053 + Q T+ V T P F L + E+ + +E + + A + W +G Sbjct: 1985 YATNKVGQAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTVNG 2044 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEII 1110 + + + G R L+I + D G Y+C + +E+ A T V++PP I+ Sbjct: 2045 KPFLAETDGVQTLAGG--RFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102 Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 V + N E+T K + +V W KDG + +Q+ +G Q+ KI + Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEG--QQFKIVHAE 2160 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIP---DET 1224 + G Y C N TA ++ + I + + + I +V A L + P D+ Sbjct: 2161 IAHKGSYICMAKNDVGTAEISFDVDIITRPM-IQKGIKNIVTAIKGGALPFKCPIDDDKN 2219 Query: 1225 L--DVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLK 1280 + W + I+ + E + R L I TE+D+ +Y+C V DA + Sbjct: 2220 FKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDF 2279 Query: 1281 VEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII--KKCKHTKP 1336 V PP I+ D ++ S VTL P+P+ W + + I + P Sbjct: 2280 KATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIP 2339 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVTILDKPSPPGKPNILEIDS 1394 + + L I +++ DAG Y +N+ G DV +NV + K G P+ E Sbjct: 2340 NGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQ 2399 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + P I ++ + + + +++ + + + L+ S ++ Sbjct: 2400 NE-RVVISCPVYARPPAKITWLKAGKPLQSDKFVKT-SANGQKLYLFKLRETDSSKYTCI 2457 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPK 1512 A NE A +KV + + +P+ ++P ++ IT L C G P P Sbjct: 2458 ATNE-----AGTDKRDFKV---SMLVAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPT 2509 Query: 1513 VTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 +TW +DG ++ ++ Y CIA N G + + + Sbjct: 2510 ITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIP 2569 Query: 1571 PVITISN-EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK---EYNITTKEK 1626 PVI E + E + G+ +V W K+G + D + I Sbjct: 2570 PVIDGERREAVAVIEGFSSELFCDSNSTGV---DVEWQKDGLTINQDTLRGDSFIQIPSS 2626 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + ++S S +YT N AG + V D PS Sbjct: 2627 GKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS 2667 Score = 187 bits (456), Expect = 3e-45 Identities = 229/1061 (21%), Positives = 423/1061 (39%), Gaps = 83/1061 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + K + G + L+C P P I ++ G+ + + + + S Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--------GS 2905 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I N +K EG YT +A N+ G + +++++ PP++ + ++ V+ G+ + Sbjct: 2906 TLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLL----PPKLSKEWINVEVQAGDPLT 2961 Query: 754 LSAQVVGNPRPTITWCKN-NKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L + ITW + K + + +S D + I++ +D Y+ A N Sbjct: 2962 LECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATP-EDADSYSCIAVNDA 3020 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G AE +TV P P +F + F + T+++ R P P I+W+ + + Sbjct: 3021 GGAEAVFQVTVNTP------PKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGK 3074 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTF 930 I +T + ++ L I N+ G Y CVA N AG++ V I + +V Sbjct: 3075 PILEMPGVT--YKQGDLSLRIDNIKPN-QEGRYTCVAENKAGRAEQDTYVEISEPPRVVM 3131 Query: 931 VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXX 987 + + EG+ + C+ + W + + + +++Q + Sbjct: 3132 ASEVMR---VVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTS----DLLQFSTKLSYLHLR 3184 Query: 988 XXXXXDVGVIKCIV--KDQETSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSET 1044 D G CI K E+ T V+ +P I + + + KE + ++ ++ Sbjct: 3185 ETTLADGGTYTCIATNKAGESQTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244 Query: 1045 AD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV- 1102 V W+R+G+ + E+ + L+IRN + DEG+YSCI +E+ TA Sbjct: 3245 VPYVTWKRNGK---------EIEQFNPV--LHIRNATRADEGKYSCIASNEAGTAVADFL 3293 Query: 1103 --VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 V P T + +G A E ++ + W K G N + + + Sbjct: 3294 IDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMDN---IILSPR 3350 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTL-RLPEFILVPANTD 1213 L I D G Y+C NS + + +P I+ T+ + P+ + A + Sbjct: 3351 GDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAV---AGGE 3407 Query: 1214 AYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 L + + T VTW + + + + T++++ L I T +D +Y+C+ ++ Sbjct: 3408 IILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNY---DLKINSVTTEDAGQYSCIAVN 3464 Query: 1273 --AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 TT EV+ P + Y + +T+ + P P+ W K + Sbjct: 3465 EAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISWFRGDKPV-- 3522 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + + SI + +TI K + +D G Y R N G +D+++ + IL P K NI+ Sbjct: 3523 YLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAGTSDIDLILKIL-VPPKIDKSNII 3581 Query: 1391 EIDSSSI--NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 + + I + P + + + +I+ T+ + I+N++ Sbjct: 3582 GNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIK-ETKIQSPTVEKPLKNIT-TEPNEDIE-LTCIF 1505 R+ A N + + + + + PT+++ IT T P + E + Sbjct: 3642 GRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701 Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 V K + DG + + R Y CIA N GE V Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGR-KLTISQASLENAGLYTCIALNRAGEASLEFKV 3760 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 I PVI IS D++ + V ++ + G P P + W KNG ++ +D+ NI E Sbjct: 3761 EILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDE--NIRIVE 3818 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + V++I H+ K++ A N AG +E+ L V+ P Sbjct: 3819 QGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPP 3859 Score = 181 bits (440), Expect = 2e-43 Identities = 248/1089 (22%), Positives = 419/1089 (38%), Gaps = 83/1089 (7%) Query: 632 IPPTFSK--KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PPT K K + E S + L C PEPDI W FK E + ENI+ I + Sbjct: 2285 VPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITW-FKDGEAIHIENIADIIPNG-E 2342 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748 + + LKIT +K+ G YT A N G + + + T K E + +S +Q Sbjct: 2343 LNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYES---QQ 2399 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLKA 807 E V++S V P ITW K KP+++ K+ + + + K ++ D YT A Sbjct: 2400 NERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSANGQKLYLFKLRET-DSSKYTCIA 2458 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G + +++ + + P + R ITV L +P P+ITW Sbjct: 2459 TNEAGTDKRDFKVSML--VAPSFDEPNIVRR---ITVNSGNPSTLHCPAKGSPSPTITWL 2513 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ I P++ FD +L I+ + D G Y C+A+NS G + + + Sbjct: 2514 KDGNAIEPNDRYVF-FDAGR-QLQISKTEGS-DQGRYTCIATNSVGSDDLENTLEVIIPP 2570 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYH-----NKKEISGMDHREIIQEGRX 981 V + +++ EG + L C ++ T V +W N+ + G +I G+ Sbjct: 2571 VIDGER-REAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKK 2629 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEV 1038 D G CIV++ + + P +L + + V V Sbjct: 2630 MSFLSARKS--DSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANI-QTIVPYYPV 2686 Query: 1039 EIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 EIN S V W D + ++P Y+ G K+ + V G Y+C ++ Sbjct: 2687 EINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV--RSQVEHAGTYTCEAQN 2744 Query: 1094 ESCTAE---VTVVELPPEIITRLQNQKVNKGNKA--TFEIELTKGDALVRWFKDGSEIQF 1148 A + V PP + G+ T E + + V W +Q Sbjct: 2745 NVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYWHAHDESVQ- 2803 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLP 1203 + I ++ L + + LDD G Y C N K ++ +E P +L Sbjct: 2804 NGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLY 2863 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 IL T P T + + K + ++++ +I TL+I ++ + Sbjct: 2864 PIILGKRLTLDCSATGTPPPT--ILFMKDGKRLNESDEVDIIGS----TLVIDNPQKEVE 2917 Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 YTC+ + +S + VEV+ PPK+ ++ G +TL + + W Sbjct: 2918 GRYTCIAENKAGRSEKDMMVEVL-LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW 2976 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + S KS L I + DA Y N+ G A+ VT+ P Sbjct: 2977 SRQFGKDGQLDMRAQSSSDKS-KLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035 Query: 1382 SPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 G + EI + + E I +++ + + I ++ K I Sbjct: 3036 KIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFL-DGKPILEMPGVTYKQ-GDLSLRI 3093 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 N+K N R+ A N+ + +E Y ++ + P V + + Sbjct: 3094 DNIKPNQEGRYTCVAENK---AGRAEQDTYVEIS-----EPPRVVMASEVMRVVEGRQTT 3145 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX-XYKCIAFNDHGEV 1559 + C G P+P V W +DG+ + + + Y CIA N GE Sbjct: 3146 IRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAGES 3205 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 +T+ V + P I +E+ + K G+ ++V + G P P V W +NG ++E ++ Sbjct: 3206 QTTTDVEVLVPP--RIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIE---QF 3260 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 N V+ I+ R+ KY+ ASN AGT+ + + V+ KP+ + Sbjct: 3261 N-------PVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE 3313 Query: 1680 RESVTIEWK 1688 ES IE K Sbjct: 3314 GESAKIECK 3322 Score = 180 bits (437), Expect = 5e-43 Identities = 229/1065 (21%), Positives = 423/1065 (39%), Gaps = 85/1065 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + V EG + C + PEP + WL GE D ++ + Sbjct: 3126 PPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSD-----LLQFSTKL-- 3178 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S L + GTYT +A N+ GE+ +++ PP++ + + + ++G + Sbjct: 3179 SYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLV----PPRIEDEERVLQGKEGNTY 3234 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ QV G P P +TW +N K ++ + + ++ DEG Y+ A N G Sbjct: 3235 MVHCQVTGRPVPYVTWKRNGKEIEQF--------NPVLHIRNATRADEGKYSCIASNEAG 3286 Query: 813 IAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 A +I V +PT E E + E + K+ ++ +P P+I+W + Sbjct: 3287 TAVADFLIDVFTKPTFETHE--------TTFNIVEGESAKIECKIDGHPKPTISWLKGGR 3338 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + + I + G+ + ++ D G Y CVA+NS G S +V + K Sbjct: 3339 PFN-MDNIILSPRGDTLMILKA---QRFDGGLYTCVATNSYGDSEQDFKVNV-YTKPYID 3393 Query: 932 KHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 + + ++ + G +IL+C + T + W + I+ Sbjct: 3394 ETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNN---YDLKINSV 3450 Query: 990 XXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEINSE-T 1044 D G CI V + T E I P F+RK + +EV E D ++ + S Sbjct: 3451 TTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPL 3510 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102 + W R G+ ++Y G + I + D G+Y C +E+ T+++ + Sbjct: 3511 PSISWFR-GDKPVYLYDRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLIL 3567 Query: 1103 -VELPPEI--ITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDG 1158 + +PP+I + N E ++ V W K+G +I ++ ++ + Sbjct: 3568 KILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS-RVILAQ 3626 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTA-------ILTVEEPSINFTLRL--PEFILVP 1209 + I + + D G Y+C N A +L+ E I+ T E + Sbjct: 3627 NNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTIT 3686 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 L +I D+ +DV+W K ++ D ISD R L I + + ++ YTC Sbjct: 3687 LTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISD-DGRKLTISQASLENAGLYTC 3745 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 + L+ L+ +V P ++D R + ++ + P P+ +W+ N Sbjct: 3746 IALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTIMRCAVTGHPFPSIKWLKNG 3805 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 K + ++ + I + L I + ++ AG + EN+ G ++EM + + P Sbjct: 3806 KEVTDDENIR--IVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSV 3863 Query: 1386 K-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444 K N ++ +I + + N + + D+ + + ++ + I +LK Sbjct: 3864 KSDNPIKALGETITLFCNASGNP-YPQLKWAKGGSLIFDSPDGARI-SLKGARLDIPHLK 3921 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + A+N S+AS + + V+ +I ++ + + + L C+ Sbjct: 3922 KTDVGDYTCQALNAAGTSEASVSVD---VLVPPEINRDGIDMSPR---LPAQQSLTLQCL 3975 Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P++ W +G L T T + Y C A N G Sbjct: 3976 AQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQINNVSLSDKGVYTCYAENVAGSDNL 4035 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 V + Q PV ISN KQ + G+ ++ ++EG P P+V W +NGN++E + + Sbjct: 4036 MYNVDVVQAPV--ISNGGTKQVIE-GELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GV 4091 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 ++ I E + S Y A+N AG++ TL+V P Sbjct: 4092 RYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSP 4136 Score = 177 bits (431), Expect = 3e-42 Identities = 270/1198 (22%), Positives = 453/1198 (37%), Gaps = 124/1198 (10%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V +C G P P+I W + ++ + + Y L+I + ED G FTC+A+ Sbjct: 810 VTLQCLAVGIPPPEIEWQKGNVLLATLNNPR--YTQLADGNLLITDAQIEDQGQFTCIAR 867 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646 N G S +T L+V +S +L +PP + + Sbjct: 868 NTYGQQSQSTTLMVTGLVS---------------------PVLGHVPP-------EEQLI 899 Query: 647 EGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 EG D+ L C +V P+P I W+ K ++ V +E ++ IE S+L++ E Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWI-KDDKPV-EEGPTIKIEGG----GSLLRLRGGNPKDE 953 Query: 706 GTYTVVAVNREGEASLPI-VLKIKTGE----KEPPQVIEPLKSMI-------------VR 747 G YT +AV+ G ++L I V IK E E V +P S + V Sbjct: 954 GKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVL 1013 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKD-EGVYTL 805 GE + V G P P ITW + +P+ P D T T++ K K GVYT Sbjct: 1014 DGEGFAIPCVVSGTPPPIITWYLDGRPI--TPNSRDFTVTADNTLIVRKADKSYSGVYTC 1071 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A NS G E I + P+ + + V +P P IT Sbjct: 1072 QATNSAGDNEQKTTIRI-------MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVIT 1124 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + + T+ E+ L I NV +E G + C A N+AG + +T+ Sbjct: 1125 W------LLDDKPFTEGVVNEDGSLTIPNV-NEAHRGTFTCHAQNAAGNDTRTVTLTVHT 1177 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTS---HTVSTKWYHNKKEISGMDHREIIQEGRXX 982 ++ +K + ++LEC V Y +K S + I ++G Sbjct: 1178 TPTINAENQEKI--ALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG--- 1232 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 + GV C V + L T+ E + + + V +EI Sbjct: 1233 ALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPC 1292 Query: 1043 ETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 V W ++G +K + K+ + G +R I +D G Y+C++ +E+ T Sbjct: 1293 RATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR---IYEADKNDIGNYNCVVTNEAGT 1349 Query: 1098 AEVTV---VELPPEIITRLQ-NQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152 +++T V+ PP I+ Q N G++ + + A V WF+ G I Sbjct: 1350 SQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG--IAIGTDT 1407 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTA---ILTVEEPSINFTLRLPEFIL 1207 + + L I ++DA Y+C+ N K A + + P I + + + Sbjct: 1408 KGYVVESDGTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESI 1467 Query: 1208 VPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 ++ + + ++WY K +I+D + D KR L + K D Y Sbjct: 1468 KESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD--KRKLHVFKAKITDSGVY 1525 Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 CV +A +V P +D Y+++ K G +VTL FP P W+V Sbjct: 1526 KCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVV 1585 Query: 1324 NSKIIKKCKHTK-PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + +++ K K ++ + +L V G Y ++ D+++ +++L P Sbjct: 1586 DGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPI 1645 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 N+ I++ D + + T + + E D + + + + + I + Sbjct: 1646 VGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQIPS-DGHRLYITD 1704 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 K ++ ++ N + +E T V++ P E K I P I L Sbjct: 1705 AKPENNGKYMCRVTNS---AGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNP---IILQ 1758 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 C G P+P V W DG + + ++ C A N G Sbjct: 1759 CQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLRIEKLTGKSAQISCTAENKAGTASRD 1817 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNI 1621 IQ T NE ++ E + + ++ W K G L END I Sbjct: 1818 FF--IQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQITWMKQGLPLTENDA---I 1872 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 T + T + I R H YT A+NTAG S + + V P K + V+ EI+ Sbjct: 1873 FTLDNTR-LTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLP-KIKNAVVTLEIN 1928 Score = 157 bits (380), Expect = 4e-36 Identities = 244/1092 (22%), Positives = 419/1092 (38%), Gaps = 106/1092 (9%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GES 751 + + +K G YT + N GEA + +PP + + L S ++ Sbjct: 2630 MSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN----DPPSISDELSSANIQTIVPYYP 2685 Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V ++ V G+P P + W ++KP++ A ++G+T I +V+ G YT +A Sbjct: 2686 VEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV---RSQVEHAGTYTCEA 2742 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITW 866 +N+ G A ++ V PP F +E+ + T+ L + P+ S+ W Sbjct: 2743 QNNVGKARKDFLVRV-------TAPPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVYW 2795 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + ++E + + IT + L +TN+ + D G Y C A N AG + ++ + +E Sbjct: 2796 HAHDESVQ-NGVITSKYAANEKTLNVTNIQLD-DEGFYYCTAVNEAGITKKFFKLIV-IE 2852 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXX 984 F+ QK Y GK + L+C + T + + + K ++ D +II Sbjct: 2853 TPYFLDQ-QKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII----GSTL 2907 Query: 985 XXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 G CI +++ M+V P+ ++ + EV+ D LE I Sbjct: 2908 VIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIE 2967 Query: 1042 SETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + + W R + K + + KLYI + D YSCI +++ AE Sbjct: 2968 DTSGVHITWSR--QFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEA 3025 Query: 1101 T---VVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSEIQFSNHIQL 1154 V PP+I + + T EI T+G + WF DG I + Sbjct: 3026 VFQVTVNTPPKIFGDSFSTTEIVAD-TTLEIPCRTEGIPPPEISWFLDGKPILEMPGV-- 3082 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 T L+I + + G Y+C + G ++ + + EP + E + V Sbjct: 3083 TYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPR--VVMASEVMRVVE 3140 Query: 1211 NTDAYLTVEI---PDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + E+ P+ V W K + D +F+ K L +R+ T D Y Sbjct: 3141 GRQTTIRCEVFGNPEPV--VNWLKDGEPYTSDLLQFS----TKLSYLHLRETTLADGGTY 3194 Query: 1267 TCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 TC+ + +S T VEV+ PP+I D ER + K G+ + P P W N Sbjct: 3195 TCIATNKAGESQTTTDVEVL-VPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN 3253 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 K I+ + L I+ D G Y N G A + + + KP+ Sbjct: 3254 GK----------EIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPT-- 3301 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI------SVKNITKTQT 1438 E ++ NI G S I ++ T W+ ++ NI + Sbjct: 3302 -----FETHETTFNIV------EGESAKIECKIDGHPKPTISWLKGGRPFNMDNIILSPR 3350 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNE 1497 L + RF V + ++ + +KV TK T+++ K + Sbjct: 3351 G-DTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETIDQTPKAVA---GG 3406 Query: 1498 DIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 +I L C G P P VTW R D ++ T N Y CIA N+ Sbjct: 3407 EIILKCPVLGNPTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEA 3466 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + T + KP ++ + + D + + P P + W++ + Sbjct: 3467 GNLTTHYAAEVIGKPTFVRKGGNLYEVIE-NDTITMDCGVTSRPLPSISWFRGDKPVYLY 3525 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 Y+I+ S I I + K S KY ASN AGTS +++ LK+ P + +I Sbjct: 3526 DRYSISPDG--SHITINKAKLSDGGKYICRASNEAGTSDIDLILKILVPPKIDKSNIIGN 3583 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 ++ + TI + P+ G+ K+ D N + ++ ET+ I+ + + Sbjct: 3584 PLAIVARTIYLECPI--SGIPQPDVIWTKNGMDINMTDSRVILAQNNETFGIENVQVTDQ 3641 Query: 1737 YMFRVIAQNPVG 1748 + A N G Sbjct: 3642 GRYTCTATNRGG 3653 Score = 155 bits (377), Expect = 1e-35 Identities = 223/1013 (22%), Positives = 380/1013 (37%), Gaps = 81/1013 (7%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L I + K G+Y N G A+ L ++ PP ++ V + S++L Sbjct: 2063 LHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQV----PPTIVNEGGEYTVIENNSLVL 2118 Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 +V G P P +TW K+ +PV K++ S+G I ++ +G Y A+N Sbjct: 2119 PCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIV---HAEIAHKGSYICMAKNDV 2175 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG---TIKLVARVTRNPVPSITWYR 868 G AE S + + P+ + I KG K +N I W R Sbjct: 2176 GTAEISFDVDI-------ITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLR 2228 Query: 869 NNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 N + I +E + L I NV +E D G Y C N AG++S + T+ V Sbjct: 2229 NYQPIDLEAEDARITRLSNDRRLTILNV-TENDEGQYSCRVKNDAGENSFDFKATVLVPP 2287 Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG--RXXX 983 + K+ E TV L C + W+ + + I + +II G Sbjct: 2288 TIIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ 2347 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRK--LQDFEVKEKDVAILEV 1038 D G C + S V TIP+ + D+E ++ + ++ Sbjct: 2348 LKITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC 2407 Query: 1039 EINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 + + A + W + G KP ++ + + +KLY+ D +Y+CI +E+ T Sbjct: 2408 PVYARPPAKITWLKAG---KPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAGT 2464 Query: 1098 ----AEVTVVELP----PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147 +V+++ P P I+ R+ VN GN +T KG + W KDG+ I+ Sbjct: 2465 DKRDFKVSMLVAPSFDEPNIVRRI---TVNSGNPSTLHCP-AKGSPSPTITWLKDGNAIE 2520 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLP 1203 N + D +Q L+I + D G Y+C VG+ L V P + R Sbjct: 2521 -PNDRYVFFDAGRQ-LQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGER-R 2577 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDT---EKFTLISDVKKRTLIIRKCT 1259 E + V + L + +DV W K I +DT + F I K+ + Sbjct: 2578 EAVAVIEGFSSELFCDSNSTGVDVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFL-SAR 2636 Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFP 1315 + D YTC++ + A KL V PP I D I+ V + P Sbjct: 2637 KSDSGRYTCIVRNPAGEARKLFDFAVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSP 2696 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P W+ + K ++ + + +L I + + AG Y +NN G A + V Sbjct: 2697 HPKVYWLFDDKPLEP-DSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLV 2755 Query: 1376 TILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI 1433 + P + + + + + C E++ + +Y+ + + S Sbjct: 2756 RVTAPPHFEKEREEVVARVGDTMLLTC--NAESSVPLSSVYWHAHDESVQNGVITSKYAA 2813 Query: 1434 TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 + ++ N++ + + AVNE I T +++K+I I++P K Sbjct: 2814 NEKTLNVTNIQLDDEGFYYCTAVNEAGI-----TKKFFKLI---VIETPYFLDQQKLYPI 2865 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + + L C G P P + + +DGK+L + Y CIA Sbjct: 2866 ILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIGSTLVIDNPQKEVEGRYTCIAE 2925 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N G E +V + P +S E I + + GD + IE + W + K Sbjct: 2926 NKAGRSEKDMMVEVLLPP--KLSKEWINVEVQAGDPLTLECPIEDTSGVHITWSRQFGK- 2982 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + + S + I + + Y+ A N AG + + V P Sbjct: 2983 DGQLDMRAQSSSDKSKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNTPP 3035 Score = 155 bits (375), Expect = 2e-35 Identities = 250/1241 (20%), Positives = 449/1241 (36%), Gaps = 107/1241 (8%) Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 + +N A F T L + DH T D++ + P Sbjct: 1866 LTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVTL 1925 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 ++EG +I+L C P P W F ++ P E + V ++ H + + NV K+ Sbjct: 1926 EINEGEEIILTCDAEGNPTPTAKWDFNQGDL-PKEAVFV---NNNH----TVVVNNVTKY 1977 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G Y A N+ G+A I + ++T + + E + V S+ L V Sbjct: 1978 HTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTE--SELTVNLTRSITLECDVDDAIG 2035 Query: 764 PTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 I+W N KP A + T + G I K D G Y N G+A + Sbjct: 2036 VGISWTVNGKPFLAETDGVQTLAGGRFLHIV---SAKTDDHGSYACTVTNEAGVATKTFN 2092 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 + V+ PP +N E TV E ++ L VT P P +TW ++ + +++ Sbjct: 2093 LFVQ-------VPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSV 2145 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT---FVKHLQK 936 +G+ ++V + G Y C+A N G A ++ DV+ +T K ++ Sbjct: 2146 QVLSEGQQFKIVHAEI---AHKGSYICMAKNDVGT----AEISFDVDIITRPMIQKGIKN 2198 Query: 937 SYETEEGKTVILECQTSHTVSTK----WYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXX 991 +G + +C + K W N + I + I + Sbjct: 2199 IVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTE 2258 Query: 992 XDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQD---FEVKEKDVAILEVEINSETA 1045 D G C VK+ K T+ P I +D V+ V + Sbjct: 2259 NDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGKPEP 2318 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTSVHDEGEYSCILRDESCTAE---- 1099 D+ W +DGE I +N D G + +L I D G+Y+C + + + E Sbjct: 2319 DITWFKDGEAIH-IENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQDVN 2377 Query: 1100 VTVVELPPEIITRLQNQKVNKGN-KATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157 V V+ +P + + ++ N + + + A + W K G +Q ++ + + Sbjct: 2378 VNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTSAN 2437 Query: 1158 GKKQKLKIYDCDLDDAGEYSC----EVGNSKCT-AILTVEEPSINFTLRLPEFILVPANT 1212 G QKL ++ D+ +Y+C E G K + + PS + + + N Sbjct: 2438 G--QKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPSFDEPNIVRRITVNSGNP 2495 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 + +TW K + IE +++ R L I K DQ YTC+ + Sbjct: 2496 STLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFD--AGRQLQISKTEGSDQGRYTCIATN 2553 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + + L+ + P ++D ER + G L D + + EW + I + Sbjct: 2554 SVGSDDLENTLEVIIPPVIDGERREAVAVIEGFSSELFCDSNS-TGVDVEWQKDGLTINQ 2612 Query: 1331 CKHTKPS---IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 S I S ++ +D+G Y + N G A + + D PS Sbjct: 2613 DTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPS----- 2667 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN- 1446 + + SS NI P I VV W+ + ++ L N Sbjct: 2668 --ISDELSSANIQTIVPY---YPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNG 2722 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIELTC 1503 + + V K K+ ++ P EK + + + + LTC Sbjct: 2723 ETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVGDTMLLTC 2782 Query: 1504 -IFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 VP V W+ + ++ T + N Y C A N+ G Sbjct: 2783 NAESSVPLSSVYWHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGIT 2842 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 + + + + P ++ +G + G PPP +++ K+G +L E Sbjct: 2843 KKFFKLIVIETPYFL--DQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEV 2900 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 +I S + I ++ +YT A N AG S ++ ++V P + + + + Sbjct: 2901 DII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQA 2956 Query: 1680 RESVTIEWKPPLDDGGLELT---KYAIE-------KHEPDNNRWIKVADVDRDVETYCIQ 1729 + +T+E P D G+ +T ++ + + D ++ + D ++Y Sbjct: 2957 GDPLTLEC-PIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSKLYIMQATPEDADSYSCI 3015 Query: 1730 KLNE--NCEYMFRVIAQNPVG-FSEALESEPIVIKTALDVP 1767 +N+ E +F+V P F ++ + IV T L++P Sbjct: 3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIP 3056 Score = 154 bits (374), Expect = 2e-35 Identities = 197/794 (24%), Positives = 327/794 (41%), Gaps = 74/794 (9%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 A++ G PT + P V+ + L+C V IP P+I W KG ++ N + Sbjct: 785 ANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGNVLLATLNNPRYTQ 843 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + L IT+ + +G +T +A N G+ S L + TG P P + + Sbjct: 844 ----LADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMV-TGLVSPVLGHVPPEEQL 898 Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 + +G+ + LS VV G P+P+I W K++KPV+ PT S+ L+ KDEG YT Sbjct: 899 I-EGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYT 957 Query: 805 LKAENSEG----------IAETSAVITVE-----EPTEENAEPP--LFINRFQEITVKEK 847 A + G I + V E +PT + +N ++ E Sbjct: 958 CIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEG 1017 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVDSEIDSGDYKC 906 I V V+ P P ITWY + I+P S T D L++ D SG Y C Sbjct: 1018 FAIPCV--VSGTPPPIITWYLDGRPITPNSRDFTVTADN---TLIVRKADKSY-SGVYTC 1071 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHN 963 A+NSAG + + TI + + Q S+ + C V T + Sbjct: 1072 QATNSAGDNEQ--KTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDD 1129 Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020 K G+ + ++G G C ++ +T T+ + T P Sbjct: 1130 KPFTEGV----VNEDGSLTIPNVNEAHR---GTFTCHAQNAAGNDTRTVTLTVHTTPTIN 1182 Query: 1021 RKLQDFEVKEKDVAILEVEINSETADV-VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 + Q+ + D +LE + V +W +GE I + + + G L ++N Sbjct: 1183 AENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDG---ALVLQNV 1239 Query: 1080 SVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQN-QKVNKGNKATFEIELTKGD 1134 + + G + C + ++S + +TV E P+II+ + V KG T Sbjct: 1240 KLENTGVFVCQVSNLAGEDSLSYTLTVHE-KPKIISEVPGVVDVVKGFTIEIPCRATGVP 1298 Query: 1135 ALVR-WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAIL 1189 ++R W K+G +++ + ++D L+IY+ D +D G Y+C E G S+ T + Sbjct: 1299 EVIRTWNKNGIDLKMDEK-KFSVD-NLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHV 1356 Query: 1190 TVEEPSINF-TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI-EDTEKFTLISD 1247 V+EP I + + +V + VE VTW+++ I DT+ + + SD Sbjct: 1357 DVQEPPIILPSTQTNNTAVVGDRVELKCYVE-ASPPASVTWFRRGIAIGTDTKGYVVESD 1415 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSD 1304 TL+I+ + +D YTC + K+ L+V V+ P K D + IK Sbjct: 1416 ---GTLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 +L + P P W +N K + K + + D K L + K + TD+G+YK N Sbjct: 1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDK-RKLHVFKAKITDSGVYKCVARN 1531 Query: 1365 NCGHADVEMNVTIL 1378 G V ++ Sbjct: 1532 AAGEGSKSFQVEVI 1545 Score = 153 bits (372), Expect = 4e-35 Identities = 255/1182 (21%), Positives = 445/1182 (37%), Gaps = 104/1182 (8%) Query: 523 DGSTVQFECQVE-GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G + C V G P+P I W + KP ++ + + L +R P+D G + Sbjct: 900 EGQDLTLSCVVVLGTPKPSIVWIKDD---KPVEEGPTIKIEGGGSLLRLRGGNPKDEGKY 956 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 TC+A + AG +ST + V+ E + + E + Sbjct: 957 TCIAVSPAG--NSTLHINVQLIKKP---EFVYKPEGGIVFKPTISGMDEKHVAVVNS--- 1008 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 V +G + C + P P I W G I P+ + +D + L + Sbjct: 1009 THDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSR-DFTVTAD-----NTLIVRKAD 1062 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 K G YT A N G+ ++I P + S + + + V G+ Sbjct: 1063 KSYSGVYTCQATNSAGDNEQKTTIRI----MNTPMISPGQSSFNMVVDDLFTIPCDVYGD 1118 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P+P ITW ++KP DG S+TI + G +T A+N+ G + +T Sbjct: 1119 PKPVITWLLDDKPFTEGVVNEDG---SLTIPNVNEA-HRGTFTCHAQNAAGNDTRTVTLT 1174 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V NAE QE + I L P P W E I S+ I Sbjct: 1175 VHTTPTINAEN-------QEKIALQNDDIVLECPAKALPPPVRLWTYEGEKID-SQLIPH 1226 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 E+ LV+ NV E ++G + C SN AG+ S +T+ EK + + + Sbjct: 1227 TI-REDGALVLQNVKLE-NTGVFVCQVSNLAGEDSLSYTLTVH-EKPKIISEVPGVVDVV 1283 Query: 942 EGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 +G T+ + C+ + V W N ++ MD ++ + D+G C Sbjct: 1284 KGFTIEIPCRATGVPEVIRTWNKNGIDLK-MDEKKFSVD-NLGTLRIYEADKNDIGNYNC 1341 Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-----SETADVVWERDGE 1054 +V ++ ++ + + E L + V VE+ S A V W R G Sbjct: 1342 VVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGI 1401 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVELP---- 1106 I Y E G L I++ SV D Y+C + + AE VTV+ P Sbjct: 1402 AIGTDTKGYVVESDG---TLVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKD 1458 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P+++T+ + + + + + + + W+ + + T D K+ KL + Sbjct: 1459 PDVVTQ---ESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKR-KLHV 1514 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEF-ILVPANTDAYLTVEIPDE 1223 + + D+G Y C N+ + + E + L ++ V A +T+ P Sbjct: 1515 FKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVS 1574 Query: 1224 TL---DVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 + W +V+E +K+ TL +D TL + + Y CV + Sbjct: 1575 GFPVPQINWVVDGTVVEPGKKYKGATLSND--GLTLHFDSVSVKQEGNYHCVAQSKGNIL 1632 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTK 1335 + VE+ IV + + G D++L D Q W +N + + + Sbjct: 1633 DIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSINGSESDRPDNVQ 1692 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEI 1392 D +T K EN G Y R+ N+ G A+ + + +L+ P P + N I Sbjct: 1693 IPSDGHRLYITDAKPENN--GKYMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLI 1750 Query: 1393 DSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 ++ I + + + TGN + + ++ ++D + W+ ++++ + I+ L T S + Sbjct: 1751 GNNPIIL---QCQVTGNPKPTVIWKIDGNDVDKS-WLFDESLSLLR--IEKL-TGKSAQI 1803 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT-EPNEDIELTCIFGGVPQ 1510 A N+ + + +++ I +PT + T +E I L C + Sbjct: 1804 SCTAENKA----GTASRDFF----IQNIAAPTFKNEGDQETIFRESETITLDCPV-SLGD 1854 Query: 1511 PKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 ++TW + G L A + + Y C+A N G+V V +Q Sbjct: 1855 FQITWMKQGLPLTENDAIFTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVVQV 1914 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 P I N + + G+E ++T EG P P W N L KE T V Sbjct: 1915 LP--KIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDFNQGDL--PKEAVFVNNNHTVV 1970 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 + + + H+ Y A+N G + + + V KP G Sbjct: 1971 --VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESG 2010 Score = 145 bits (351), Expect = 1e-32 Identities = 245/1099 (22%), Positives = 431/1099 (39%), Gaps = 110/1099 (10%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP SK+ V G + LEC + I W + D + + +S Sbjct: 2941 LPPKLSKEWINVEVQAGDPLTLECPIEDTSGVHITW---SRQFGKDGQLDMRAQSSSDK- 2996 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGE 750 S L I +Y+ +AVN G A + + T PP++ + + + Sbjct: 2997 -SKLYIMQATPEDADSYSCIAVNDAGGAEAVFQVTVNT----PPKIFGDSFSTTEIVADT 3051 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTH-SITILKPKKVKDEGVYTLKA 807 ++ + + G P P I+W + KP+ +P T GD I +KP + EG YT A Sbjct: 3052 TLEIPCRTEGIPPPEISWFLDGKPILEMPGVTYKQGDLSLRIDNIKPNQ---EGRYTCVA 3108 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 EN G AE + + +EPP + + + V E + V NP P + W Sbjct: 3109 ENKAGRAEQDTYVEI-------SEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWL 3161 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ E + S+ + + + L T + D G Y C+A+N AG+S + T DVE Sbjct: 3162 KDGEPYT-SDLLQFSTKLSYLHLRETTL---ADGGTYTCIATNKAGES----QTTTDVEV 3213 Query: 928 VT--FVKHLQKSYETEEGKTVILECQ-TSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX 983 + ++ ++ + +EG T ++ CQ T V W N KEI + I+ Sbjct: 3214 LVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIRNA---- 3269 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G CI ++ + + L+ T P F F + E + A +E +I Sbjct: 3270 ------TRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVEGESAKIECKI 3323 Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + + W + G + RG L I D G Y+C+ + +E Sbjct: 3324 DGHPKPTISWLKGGRPFN--MDNIILSPRGDT--LMILKAQRFDGGLYTCVATNSYGDSE 3379 Query: 1100 ----VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLT 1155 V V P T Q K G + + + +K G + N + T Sbjct: 3380 QDFKVNVYTKPYIDETIDQTPKAVAGGEIILKCPVLGNPTPTVTWKRGDDA-VPNDSRHT 3438 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPA 1210 I LKI +DAG+YSC E GN + A + +P+ F + V Sbjct: 3439 IVNNYD-LKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPT--FVRKGGNLYEVIE 3495 Query: 1211 NTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 N + + L ++W++ + +++++ D T I K D +Y C Sbjct: 3496 NDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHIT--INKAKLSDGGKYICR 3553 Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY-----QAFPQPNDEWIV 1323 + T+ + + + + PPKI ++ I + Y PQP+ W Sbjct: 3554 ASNEAGTSDIDLILKILVPPKI---DKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTK 3610 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS- 1382 N I ++ + + + I+ V+ TD G Y N G A + ++ +L P Sbjct: 3611 NGMDINMTD-SRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEF 3669 Query: 1383 --PPGKPNIL-EIDSSSINICWDEPENTGNSTI-IYYVVEYQEID--TTEWISVKNITKT 1436 +P I E D+ ++ E+ + + + + + + +D T+ + + + + Sbjct: 3670 DIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRK 3729 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP- 1495 T Q N+ + A+N A E + +KV +I SP V +N +P Sbjct: 3730 LTISQASLENAGL-YTCIALNR-----AGEASLEFKV----EILSPPVIDISRN-DVQPQ 3778 Query: 1496 ---NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKC 1550 N+ + C G P P + W ++GK++ + E + C Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDSDHAGKWSC 3838 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 +A ND G E V+ + PV+++ +++ IK +G+ + G P P++ W K Sbjct: 3839 VAENDAGVKELEMVLDVFTPPVVSVKSDNPIKA---LGETITLFCNASGNPYPQLKWAKG 3895 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 G+ L D K + + I LK++ YT +A N AGTS V++ V P Sbjct: 3896 GS-LIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEIN 3954 Query: 1670 EGPVIM--REISRESVTIE 1686 + M R +++S+T++ Sbjct: 3955 RDGIDMSPRLPAQQSLTLQ 3973 Score = 141 bits (341), Expect = 2e-31 Identities = 241/1190 (20%), Positives = 427/1190 (35%), Gaps = 123/1190 (10%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLV 569 I ++K + K + STV C G P P ITWF+ I + + + N L Sbjct: 2290 IMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLK 2349 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I + DAG +TC A N+AG + ++ P + Sbjct: 2350 ITRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEK--------------------- 2388 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 +GIP + + + +++ C + A P I WL G+ + D+ + + + Sbjct: 2389 -DGIPSDYESQ-------QNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS-ANGQ 2439 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVR 747 +Y L+ T+ K YT +A N G + + + P ++ + + V Sbjct: 2440 KLYLFKLRETDSSK-----YTCIATNEAGTDKRDFKVSMLVAPSFDEPNIV---RRITVN 2491 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 G L G+P PTITW K+ ++ D + + D+G YT A Sbjct: 2492 SGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQISKTEGSDQGRYTCIA 2551 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 NS G + + V P P + R + + V E + +L V + W Sbjct: 2552 TNSVGSDDLENTLEVIIP------PVIDGERREAVAVIEGFSSELFCDSNSTGV-DVEWQ 2604 Query: 868 RNNEIISPSETITQNF-----DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 ++ I+ +F G+ + + + DSG Y C+ N AG+ AR Sbjct: 2605 KDGLTINQDTLRGDSFIQIPSSGKKMSFLSAR---KSDSGRYTCIVRNPAGE----ARKL 2657 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVI------LECQTSHTVSTK--WYHNKKEISGMDHRE 974 D V + + +T++ + C S + K W + K + D Sbjct: 2658 FDF-AVNDPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLE-PDSAA 2715 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEK 1031 G C ++ + LV P F ++ ++ + Sbjct: 2716 YELTNNGETLKIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHFEKEREEVVARVG 2775 Query: 1032 DVAILEVEINSET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 D +L S + V W E + + + + + L + N + DEG Y C Sbjct: 2776 DTMLLTCNAESSVPLSSVYWHAHDESV--QNGVITSKYAANEKTLNVTNIQLDDEGFYYC 2833 Query: 1090 ILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144 +E+ ++ V+E P + + + + G + T + T + + KDG Sbjct: 2834 TAVNEAGITKKFFKLIVIE-TPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGK 2892 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204 + S+ + + L I + + G Y+C N + + + E Sbjct: 2893 RLNESDEVDII----GSTLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKE 2948 Query: 1205 FILVPANTDAYLTVEIPDET---LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 +I V LT+E P E + +TW ++ + S K + L I + T + Sbjct: 2949 WINVEVQAGDPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDKSK-LYIMQATPE 3007 Query: 1262 DQCEYTCVLL-DAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPND 1319 D Y+C+ + DA + V PPKI D I + + + + P P Sbjct: 3008 DADSYSCIAVNDAGGAEAVFQVTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEI 3067 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W ++ K I + P + K SL I ++ G Y EN G A+ + V I Sbjct: 3068 SWFLDGKPILE----MPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEI 3123 Query: 1378 LDKPSPPGKPNILE-IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 + P ++ ++ I E GN + ++ E T++ + T Sbjct: 3124 SEPPRVVMASEVMRVVEGRQTTI---RCEVFGNPEPVVNWLKDGEPYTSDLLQF----ST 3176 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + S +L+ + Y + + S+TT +V + P +E + + + Sbjct: 3177 KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEV-----LVPPRIEDEERVLQGKEG 3231 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + C G P P VTW R+GK+++ R Y CIA N+ Sbjct: 3232 NTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPVLHIR------NATRADEGKYSCIASNEA 3285 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G ++ + KP T + G+ + I+G P P + W K G D Sbjct: 3286 GTAVADFLIDVFTKP--TFETHETTFNIVEGESAKIECKIDGHPKPTISWLKGGRPFNMD 3343 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 NI + + I + +R YT A+N+ G S + + VY KP Sbjct: 3344 ---NIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKP 3390 Score = 138 bits (335), Expect = 1e-30 Identities = 248/1116 (22%), Positives = 432/1116 (38%), Gaps = 104/1116 (9%) Query: 599 IVEAPLSDHGSEMT-VXXXXXXXXXXXXADILEGIPPTFSKK--PKAQYVDEGSDILLEC 655 I +A ++G M V D+LE PP F + Q + + I+L+C Sbjct: 1702 ITDAKPENNGKYMCRVTNSAGKAERTLTLDVLE--PPVFVEPVFEANQKLIGNNPIILQC 1759 Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 ++ P+P + W G ++ + S + + S+L+I + + + A N+ Sbjct: 1760 QVTGNPKPTVIWKIDGNDV----DKSWLFDESL----SLLRIEKLTG-KSAQISCTAENK 1810 Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKP 774 G AS ++ P E + I R+ E++ L V +G+ + ITW K P Sbjct: 1811 AGTASRDFFIQ---NIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ--ITWMKQGLP 1865 Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPP 833 + D +TIL + E +YT A N+ G +++ V+ P +NA Sbjct: 1866 LTENDAIFTLDNTRLTILNANR-DHEDIYTCVANNTAGQVSKDFDVVVQVLPKIKNAVVT 1924 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893 L IN +EI L NP P+ W N + P E + F N +V+ Sbjct: 1925 LEINEGEEII--------LTCDAEGNPTPTAKWDFNQGDL-PKEAV---FVNNNHTVVVN 1972 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVILECQT 952 NV ++ +G YKC A+N G++ V + K F L +S T +++ LEC Sbjct: 1973 NV-TKYHTGVYKCYATNKVGQAVKTINVHVRT-KPRFESGLTESELTVNLTRSITLECDV 2030 Query: 953 SHT--VSTKWYHNKKE-ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ET 1006 V W N K ++ D + + GR D G C V ++ T Sbjct: 2031 DDAIGVGISWTVNGKPFLAETDGVQTLAGGR--FLHIVSAKTDDHGSYACTVTNEAGVAT 2088 Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065 T + + P + + ++ V E + +L E+ + VV W +DG +P + Sbjct: 2089 KTFNLFVQVPPTIVNEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG---RPVGDLKSV 2145 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK-------V 1118 + ++ I + + +G Y C+ +++ TAE++ +IITR QK Sbjct: 2146 QVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEIS---FDVDIITRPMIQKGIKNIVTA 2202 Query: 1119 NKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDLDDAG 1174 KG F+ + + W ++ I + ++T ++L I + +D G Sbjct: 2203 IKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEG 2262 Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETL------- 1225 +YSC V N E S +F T+ +P I++ VE TL Sbjct: 2263 QYSCRVKND-------AGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVTLSCPATGK 2315 Query: 1226 ---DVTWYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-- 1278 D+TW+K IE+ ++ L I + E D +YTC ++ + + Sbjct: 2316 PEPDITWFKDGEAIHIENIADIIPNGELNGNQLKITRIKEGDAGKYTCEADNSAGSVEQD 2375 Query: 1279 LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 + V V+ P D +Y ++ V + A P W+ K ++ K K S Sbjct: 2376 VNVNVITIPKIEKDGIPSDYESQQNERVVISCPVYARPPAKITWLKAGKPLQSDKFVKTS 2435 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSS 1396 + + L + K+ TD+ Y N G + V++L PS +PNI+ I +S Sbjct: 2436 ANGQ--KLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLVAPS-FDEPNIVRRITVNS 2492 Query: 1397 IN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 N P S I ++ + I+ + + + Q I + + R+ A Sbjct: 2493 GNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGR-QLQISKTEGSDQGRYTCIA 2551 Query: 1456 VNEVDISDASETTEYY--KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 N V D T E VI + ++ V ++ ++E D T + + + Sbjct: 2552 TNSVGSDDLENTLEVIIPPVIDGERREAVAV---IEGFSSELFCDSNSTGVDVEWQKDGL 2608 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 T +D + + + Y CI N GE + P I Sbjct: 2609 TINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVNDPPSI 2668 Query: 1574 T--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVI 1630 + +S+ +I Q + V+ G P P+V W + LE D Y +T +T + Sbjct: 2669 SDELSSANI-QTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET--L 2725 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +I + H+ YT EA N G + + ++V P Sbjct: 2726 KIVRSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPP 2761 Score = 132 bits (319), Expect = 1e-28 Identities = 240/1100 (21%), Positives = 415/1100 (37%), Gaps = 121/1100 (11%) Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 DI+E PP+ P+ Y + + L C + P+P++ W FKG ++ D V +S Sbjct: 606 DIME--PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDS 663 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 L I + EGTY A+++ G+A L + T PP+V M+V Sbjct: 664 ------KFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLAT----PPKVEIIQNKMMV 713 Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 +G+ V + + G P P I W KN K + + + I+ K +D G Y+ Sbjct: 714 GRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIMGAKD-EDAGAYSC 772 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 EN G A ++V P I + V + + L P P I Sbjct: 773 VGENMAGKDVQVANLSV-------GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIE 825 Query: 866 WYRNNEIISP--SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + N +++ + TQ DG L+IT+ E D G + C+A N+ G+ S + + Sbjct: 826 WQKGNVLLATLNNPRYTQLADG---NLLITDAQIE-DQGQFTCIARNTYGQQSQSTTLMV 881 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGR 980 + H+ + EG+ + L C + S W + K + + I EG Sbjct: 882 TGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVE--EGPTIKIEGG 939 Query: 981 XXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETI--PEFIRKLQD---FE-----VK 1029 D G CI V ST+ + + I PEF+ K + F+ + Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999 Query: 1030 EKDVAILE---------------VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 EK VA++ V + + W DG I P N DF L Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRPITP--NSRDFTVTAD-NTL 1056 Query: 1075 YIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132 +R G Y+C + + E T + + + N F I Sbjct: 1057 IVRKADKSYSGVYTCQATNSAGDNEQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVY 1116 Query: 1133 GD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCT 1186 GD ++ W D + F+ + + DG L I + + G ++C GN T Sbjct: 1117 GDPKPVITWLLD--DKPFTEGV-VNEDG---SLTIPNVNEAHRGTFTCHAQNAAGNDTRT 1170 Query: 1187 AILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV---TW-YKKKSVIEDTEK 1241 LTV P+IN E I + N D + +E P + L W Y+ + + Sbjct: 1171 VTLTVHTTPTIN--AENQEKIAL-QNDD--IVLECPAKALPPPVRLWTYEGEKIDSQLIP 1225 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299 T+ D L+++ ++ + C + L + + + V E P I + + Sbjct: 1226 HTIRED---GALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 +G + + P+ W N I K K S+D+ +L I + + D G Y Sbjct: 1283 VKGFTIEIPCRATGVPEVIRTWNKNG-IDLKMDEKKFSVDN-LGTLRIYEADKNDIGNYN 1340 Query: 1360 LRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYV 1416 + N G + + +V + + P P + N + + + C+ E + T Sbjct: 1341 CVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRG 1400 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + DT ++ + T IQ+ + + A N ++A+ ++ Sbjct: 1401 IAI-GTDTKGYVVESDGTLV---IQSASVEDATIYTCKASNPAGKAEAN--------LQV 1448 Query: 1477 TKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYEN 1531 T I SP ++ P + + + + L C P P+++WY + K L KT+ T ++ Sbjct: 1449 TVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDD 1508 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----G 1587 + YKC+A N GE S Q + ++ ++ ++ K K KV G Sbjct: 1509 KRKLHVFKAKITDSGVYKCVARNAAGEGSKS----FQVEVIVPLNLDESKYKKKVFAKEG 1564 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIE 1646 +E + + G P P++ W +G +E K+Y T + + + Y Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQEGNYHCV 1624 Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666 A + ++V L V P Sbjct: 1625 AQSKGNILDIDVELSVLAVP 1644 Score = 125 bits (302), Expect = 1e-26 Identities = 172/797 (21%), Positives = 313/797 (39%), Gaps = 68/797 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I T + PKA G +I+L+C ++ P P + W +G++ VP+++ + + Sbjct: 3392 IDETIDQTPKAV---AGGEIILKCPVLGNPTPTVTWK-RGDDAVPNDSRHTIVNN----- 3442 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 LKI +V G Y+ +AVN G + ++ G+ P V + V + ++ Sbjct: 3443 -YDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEV-IGK--PTFVRKGGNLYEVIENDT 3498 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + + V P P+I+W + +KPV S S + K+ D G Y +A N Sbjct: 3499 ITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEA 3558 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G ++ ++ + P + + I I + TI L ++ P P + W +N Sbjct: 3559 GTSDIDLILKILVPPK--IDKSNIIGNPLAIVAR---TIYLECPISGIPQPDVIWTKNGM 3613 Query: 872 IISPSET---ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 I+ +++ + QN + IE V D G Y C A+N GK+SH + + + Sbjct: 3614 DINMTDSRVILAQNNETFGIENV-----QVTDQGRYTCTATNRGGKASHDFSLDV-LSPP 3667 Query: 929 TFVKHLQKSYETEEGKTVILECQ-------TSHTVSTKWYHNKKEISG--MDHREIIQEG 979 F H + EG T+ L C + W + + + G D+ +I +G Sbjct: 3668 EFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDDG 3727 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVA 1034 R + G+ CI ++ E S V+ P I R +V Sbjct: 3728 R--KLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPT 3785 Query: 1035 ILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 I+ + + W ++G+ + +N ++G + ++ +R S H G++SC+ + Sbjct: 3786 IMRCAVTGHPFPSIKWLKNGKEVTDDEN-IRIVEQGQVLQI-LRTDSDH-AGKWSCVAEN 3842 Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFS 1149 ++ E+ + V PP + + N G T + ++W K GS I F Sbjct: 3843 DAGVKELEMVLDVFTPPVVSVKSDNPIKALGETITLFCNASGNPYPQLKWAKGGSLI-FD 3901 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPE 1204 + I K +L I D G+Y+C+ N+ T+ +V P IN + Sbjct: 3902 SPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASVSVDVLVPPEINRD-GIDM 3960 Query: 1205 FILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 +PA L + + + W ++ T T+ SD + I + D Sbjct: 3961 SPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASD--STFIQINNVSLSD 4018 Query: 1263 QCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 + YTC + + L V+VV+ P ++ ++ G + + +P P Sbjct: 4019 KGVYTCYAENVAGSDNLMYNVDVVQAP--VISNGGTKQVIEGELAVIECLVEGYPAPQVS 4076 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W+ N ++ + + LTI + + D+GIY N G A + +L Sbjct: 4077 WLRNGNRVETGVQGVRYV-TDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVS 4135 Query: 1381 PS-PPGKPNILEIDSSS 1396 P P +L S S Sbjct: 4136 PKIITSTPGVLTPSSGS 4152 Score = 118 bits (285), Expect = 1e-24 Identities = 204/945 (21%), Positives = 362/945 (38%), Gaps = 86/945 (9%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 I LEC + IP+PD+ W G +I + D + +A ++ I NV+ +G YT Sbjct: 3592 IYLECPISGIPQPDVIWTKNGMDINMTDSRVILAQNNE------TFGIENVQVTDQGRYT 3645 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILS-----AQVVGNPR 763 A NR G+AS L + + PP+ I + I R+G+++ L+ A+ + + Sbjct: 3646 CTATNRGGKASHDFSLDVLS----PPEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQV 3701 Query: 764 PTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 ++W K+++ + T + D +TI + +++ G+YT A N G A + Sbjct: 3702 MDVSWTKDSRALDGDLTDNVDISDDGRKLTISQAS-LENAGLYTCIALNRAGEASLEFKV 3760 Query: 821 TVEEPTEENAEPPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + P P + I+R Q + TI A VT +P PSI W +N + ++ E Sbjct: 3761 EILSP------PVIDISRNDVQPQVAVNQPTIMRCA-VTGHPFPSIKWLKNGKEVTDDEN 3813 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 I G+ ++++ T+ D +G + CVA N AG + +DV V + Sbjct: 3814 IRIVEQGQVLQILRTDSDH---AGKWSCVAENDAGVKE--LEMVLDVFTPPVVSVKSDNP 3868 Query: 939 ETEEGKTVILECQTSHTV--STKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVG 995 G+T+ L C S KW I D I +G DVG Sbjct: 3869 IKALGETITLFCNASGNPYPQLKWAKGGSLIFDSPDGARISLKG--ARLDIPHLKKTDVG 3926 Query: 996 VIKC-IVKDQETSTMLVVKETI--PEFIRKLQDFEVK---EKDVAILEVEINSETADVVW 1049 C + TS V + + PE R D + ++ + + + + W Sbjct: 3927 DYTCQALNAAGTSEASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRW 3986 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL 1105 +G + + I N S+ D+G Y+C + ++ V VV+ Sbjct: 3987 TLNGTALTHSTPGITVASDSTF--IQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQA 4044 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS-NHIQLTIDGKKQKL 1163 P +I+ ++V +G A E + A V W ++G+ ++ ++ DG+ L Sbjct: 4045 P--VISNGGTKQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM--L 4100 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAY-LTVEI 1220 I + D+G Y C N +A T+E + +L P++ + L + Sbjct: 4101 TIIEARSLDSGIYLCSATNEAGSAQQAYTLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV 4160 Query: 1221 ---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275 PD ++W + I+D E I TL I K E+ Y C + Sbjct: 4161 RGYPDPI--ISWTLNGNDIKDGENGHTIG--ADGTLHIEKA-EERHLIYECTAKNDAGAD 4215 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 T + V+ + P R G++ + + ++ W N + + Sbjct: 4216 TLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFSWSKNGVPLLPSNNLI 4274 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395 S D K + ++ +D G Y N G+A + N+ + P +P + Sbjct: 4275 FSEDYKLIKILSTRL--SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKG 4332 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAY 1454 W E I +Y + E+ T + TK ++ I ++ + + + Sbjct: 4333 DQVTLWCEASGVPQPAITWY--KDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYTCK 4390 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 A N V + E + +I P V N++T P + + L+C G+P+P ++ Sbjct: 4391 AENWV--ASTEEDIDLIVMIP------PEVVPERMNVSTNPRQTVFLSCNATGIPEPVIS 4442 Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGE 1558 W RD Y+ Y CIA +D G+ Sbjct: 4443 WMRDSNIAIQNNEKYQILGTTLAIRNVLPDDDGFYHCIAKSDAGQ 4487 Score = 115 bits (277), Expect = 1e-23 Identities = 167/808 (20%), Positives = 317/808 (39%), Gaps = 71/808 (8%) Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VS 957 D+G+Y+C ++ G S RV ++ G+ L C T V Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFG--VRNVSVPLGEAAFLHCSTRSAGEVE 550 Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKE 1014 +W + + E + D GV +C+ ++ T M + Sbjct: 551 IRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMRLDIM 608 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 P QD ++ L E + +V W G + N Y ++ + Sbjct: 609 EPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLL---NDYKYQVGQDSKF 665 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIEL 1130 LYIR+ + HDEG Y C ++ A T ++ PP++ V +G++ +FE + Sbjct: 666 LYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKT 725 Query: 1131 TKGDA--LVRWFKDGSE-IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 +G +RWFK+G + I+ ++I++ + +L I +DAG YSC VG + Sbjct: 726 IRGKPHPKIRWFKNGKDLIKPDDYIKIN----EGQLHIMGAKDEDAGAYSC-VGENMAGK 780 Query: 1188 ILTVEEPSINFTLRLPEFILVP----ANTDAYLTVE---IPDETLDVTWYKKKSVIE--D 1238 + V S+ R+P I P N + +T++ + ++ W K ++ + Sbjct: 781 DVQVANLSVG---RVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLN 837 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-----AKSTTKLKVEVVEFPPKIVDY 1293 ++T ++D L+I +DQ ++TC+ + ++STT + +V P + Sbjct: 838 NPRYTQLAD---GNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS--PVLGHV 892 Query: 1294 EREYRIKRGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 E ++ G D+TL V P+P+ WI + K +++ K I+ + L ++ Sbjct: 893 PPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIK--IEGGGSLLRLRGGNP 950 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKP----SPPG----KPNILEIDSSSINICWDEP 1404 D G Y + G++ + +NV ++ KP P G KP I +D + + Sbjct: 951 KDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTH 1010 Query: 1405 E-NTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRA---YA-VNE 1458 + G I VV W + + IT N+ +A Y+ V Sbjct: 1011 DVLDGEGFAIPCVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYT 1070 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 ++++ E I+ + +P + + ++ + C G P+P +TW D Sbjct: 1071 CQATNSAGDNEQKTTIR--IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD 1128 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 K + + C A N G + + + P I N+ Sbjct: 1129 DKPF--TEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQ 1186 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 + + D+ ++ + +PPP +W G K+ D + T + + ++ +K Sbjct: 1187 E--KIALQNDDIVLECPAKALPPPVRLWTYEGEKI--DSQLIPHTIREDGALVLQNVKLE 1242 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 ++ + + SN AG S+ TL V++KP Sbjct: 1243 NTGVFVCQVSNLAGEDSLSYTLTVHEKP 1270 Score = 104 bits (250), Expect = 2e-20 Identities = 120/542 (22%), Positives = 223/542 (41%), Gaps = 36/542 (6%) Query: 1227 VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 +TWY + + ++ FT+ +D TLI+RK + YTC ++ + K + + Sbjct: 1032 ITWYLDGRPITPNSRDFTVTAD---NTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIRI 1088 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P I + + + T+ D P+P W+++ K + + ++ S Sbjct: 1089 MNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTE------GVVNEDGS 1142 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 LTI V G + +N G+ + +T+ P+ + N +I + +I + P Sbjct: 1143 LTIPNVNEAHRGTFTCHAQNAAGNDTRTVTLTVHTTPTINAE-NQEKIALQNDDIVLECP 1201 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN---EVDI 1461 + + E ++ID+ + I +QN+K ++ F N E + Sbjct: 1202 AKALPPPVRLWTYEGEKIDS-QLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSL 1260 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 S E K+I E P V +K T IE+ C GVP+ TW ++G Sbjct: 1261 SYTLTVHEKPKIISEV----PGVVDVVKGFT------IEIPCRATGVPEVIRTWNKNGID 1310 Query: 1522 LKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 LK K + +N Y C+ N+ G + + V +Q+ P+I S + Sbjct: 1311 LKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQT 1370 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 VGD + +E PP V W++ G + D + + + T VI+ ++ Sbjct: 1371 -NNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE--D 1427 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL-EL 1698 ++ YT +ASN AG + + + V P + V+ +E +ES P+ L ++ Sbjct: 1428 ATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQI 1487 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEP 1757 + Y +K D+ K +D R + + K +++ +A+N G S++ + E Sbjct: 1488 SWYLNDKPLIDDKTSWKTSDDKRKLHVF---KAKITDSGVYKCVARNAAGEGSKSFQVEV 1544 Query: 1758 IV 1759 IV Sbjct: 1545 IV 1546 Score = 86.2 bits (204), Expect = 9e-15 Identities = 119/600 (19%), Positives = 229/600 (38%), Gaps = 57/600 (9%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ G P F ++V G D+ L C + + I W+ GE+I+ ++ Sbjct: 425 VIVGGPRAFMSPIHQEFV--GRDLNLSCTVESASAYTIYWVKTGEDIIGGPLFYHNTDT- 481 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 SV I + G Y ++ G S+ K + +E P I ++++ V Sbjct: 482 -----SVWTIPELSLKDAGEYECRVISNNGNYSV----KTRVETRESPPEIFGVRNVSVP 532 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 GE+ L I W + V P T+ + D GVY A Sbjct: 533 LGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMA 592 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N+ G++ + + EP P Q++ + + L +P P + WY Sbjct: 593 RNAGGMSTRKMRLDIMEPPSVKVTP-------QDVYFNMREGVNLSCEAMGDPKPEVHWY 645 Query: 868 -RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + +++ + G++ + + + D G Y+C A + AG+ AR T D+ Sbjct: 646 FKGRHLLNDYKYQV----GQDSKFLYIRDATHHDEGTYECRAMSQAGQ----ARDTTDLM 697 Query: 927 KVT--FVKHLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKEISGMDHREIIQEGRX 981 T V+ +Q G V EC+T +W+ N K++ D I EG+ Sbjct: 698 LATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQ- 756 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKLQDFEVK-EKDVAILE 1037 D G C+ ++ + V + +P I V E+ V + Sbjct: 757 --LHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQC 814 Query: 1038 VEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--- 1093 + + ++ W++ ++ N +Y G+ L I + + D+G+++CI R+ Sbjct: 815 LAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGN---LLITDAQIEDQGQFTCIARNTYG 871 Query: 1094 -ESCTAEVTVVELPPEIITRL-QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149 +S + + V L ++ + +++ +G T + G + W KD ++ Sbjct: 872 QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEG 931 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 I+ I+G L++ + D G+Y+C + + L + I + PEF+ P Sbjct: 932 PTIK--IEGGGSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLI----KKPEFVYKP 985 Score = 85.8 bits (203), Expect = 1e-14 Identities = 108/505 (21%), Positives = 186/505 (36%), Gaps = 47/505 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V EG ++EC + P P ++WL G + V +D M L I + Sbjct: 4055 VIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQ-GVRYVTDGRM----LTIIEARSLD 4109 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGESVILSAQVVGNPR 763 G Y A N G A L++ P++I ++ G L V G P Sbjct: 4110 SGIYLCSATNEAGSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPD 4165 Query: 764 PTITWCKNNKPVKALPTKSDGDT-HSI----TILKPKKVKDEGVYTLKAENSEGIAETSA 818 P I+W N +K DG+ H+I T+ K + +Y A+N G Sbjct: 4166 PIISWTLNGNDIK------DGENGHTIGADGTLHIEKAEERHLIYECTAKNDAGAD---- 4215 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 T+E P + P + + + I E GT ++ + +W +N + PS Sbjct: 4216 --TLEFPVQTIVAPKISTSGNRYINGSE-GTETVIKCEIESESSEFSWSKNGVPLLPSNN 4272 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 + + D + I+++ T + D G+Y C A+N AG ++ + ++V + ++ Sbjct: 4273 LIFSEDYKLIKILSTRLS---DQGEYSCTAANKAGNATQ--KTNLNVGVAPKIMERPRTQ 4327 Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 +G V L C+ S + WY + + ++ E + GV Sbjct: 4328 VVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT-KKKSVIFSSISPSQAGV 4386 Query: 997 IKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD 1052 C ++ ST + ++ PE + + + + L V+ W RD Sbjct: 4387 YTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRD 4446 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEI 1109 I KY L IRN D+G Y CI + ++ T +V P + Sbjct: 4447 SNIAIQNNEKYQILG----TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKPSDR 4502 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGD 1134 + + KG E + +GD Sbjct: 4503 PAPIWVECDEKGKPKKTEYMIDRGD 4527 Score = 75.8 bits (178), Expect = 1e-11 Identities = 109/530 (20%), Positives = 199/530 (37%), Gaps = 41/530 (7%) Query: 1165 IYDCDLDDAGEYSCEV----GN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 I + L DAGEY C V GN S T + T E P F +R + VP A+L Sbjct: 486 IPELSLKDAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRN---VSVPLGEAAFLHCS 542 Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KST 1276 +++ W + + + + + TL I T D Y C+ +A ST Sbjct: 543 TRSAGEVEIRWTRYGATVFNGPNTE--RNPTNGTLKIHHVTRADAGVYECMARNAGGMST 600 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 K++++++E PP + ++ V L + P+P W + + K Sbjct: 601 RKMRLDIME-PPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHL--LNDYKY 657 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 + S L I+ + D G Y+ R + G A ++ + P N + + Sbjct: 658 QVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGD 717 Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 ++ + I ++ I ++I I + Q I K + + Sbjct: 718 RVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIK---INEGQLHIMGAKDEDAGAYSCVG 774 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 N + +V + + PT+ + + + L C+ G+P P++ W Sbjct: 775 ENMAG--------KDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEW 826 Query: 1516 YRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE---TSCVVGIQQ 1569 + L T + T + CIA N +G+ T V G+ Sbjct: 827 QKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVS 886 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 + + E+ Q + D L V+ G P P ++W K+ +E I + S+ Sbjct: 887 PVLGHVPPEE--QLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGP--TIKIEGGGSL 942 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMR 1676 +R++ KYT A + AG S++ + +++ KP KPEG ++ + Sbjct: 943 LRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFK 992 Score = 66.1 bits (154), Expect = 1e-08 Identities = 55/236 (23%), Positives = 101/236 (42%), Gaps = 19/236 (8%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 I+ LSD G E + ++ G+ P ++P+ Q V +G + L C Sbjct: 4284 ILSTRLSDQG-EYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEAS 4342 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--RE 716 +P+P I W +K E++ + + E+ SV+ +++ Q G YT A N Sbjct: 4343 GVPQPAITW-YKDNELLTNTGVD---ETATTKKKSVI-FSSISPSQAGVYTCKAENWVAS 4397 Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 E + +++ I PP+V+ ++ ++V LS G P P I+W +++ Sbjct: 4398 TEEDIDLIVMI------PPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAI 4451 Query: 777 ALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 K G T +I + P D+G Y A++ G + + V +P++ A Sbjct: 4452 QNNEKYQILGTTLAIRNVLP---DDDGFYHCIAKSDAGQKIATRKLIVNKPSDRPA 4504 Score = 63.7 bits (148), Expect = 5e-08 Identities = 60/267 (22%), Positives = 111/267 (41%), Gaps = 25/267 (9%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P FI + + T ++L P P+ITW ++ ++I S+ F+ L + Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-----FEIAYSHLKV 4624 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 T ++S DSG+Y C+A NS G S+ A + +D + K S + E Sbjct: 4625 T-LNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPK--PSSNQKNVAVITCYERNQ 4681 Query: 953 SHTVSTKWYHN----KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST 1008 +++ W +N K ++G+ + G D+ + C V+++ + Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGI---HFMNNGSLVILDTSSLKEGDLELYTCKVRNRRRHS 4738 Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE--TADVVWERDGEIIKPKKNKY 1063 + E +PE ++ + EV D +L+ E+ S+ T VVW ++ + + Y Sbjct: 4739 IPHLTSAFEGVPE-VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIY 4797 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 L + N +DEG Y C+ Sbjct: 4798 VLPN----NSLVLLNVEKYDEGVYKCV 4820 Score = 61.7 bits (143), Expect = 2e-07 Identities = 71/294 (24%), Positives = 118/294 (40%), Gaps = 31/294 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F KPK G+ + L C P P I W G+ ++ D +A S Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAY--------S 4620 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 LK+T G YT +A N G +++ + + P+ K++ +VI Sbjct: 4621 HLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNV------AVI 4674 Query: 754 LSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENS 810 + +TW N P+ K L + S+ IL +K D +YT K N Sbjct: 4675 TCYERNQAYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS-ITWYRN 869 + E E + ++ V ++ L VT +P+ + + W +N Sbjct: 4735 RRHSIPHLTSAFEGVPE--------VKTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN 4786 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ + + I + N LV+ NV+ + D G YKCVASNS GK+ ++ + Sbjct: 4787 DQKMLDDDAI---YVLPNNSLVLLNVE-KYDEGVYKCVASNSIGKAFDDTQLNV 4836 Score = 57.6 bits (133), Expect = 4e-06 Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 19/271 (7%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 PQ I K+ G V L G P PTITW K+ K ++ + +T+ Sbjct: 4570 PQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIAYSHLKVTL--- 4626 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 D G YT A+NS G + SA I V+ +P IT E+ + + Sbjct: 4627 NSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSSNQKNVAVITCYERN--QAYS 4684 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 R +TW N + P +F N LVI + S + GD + + Sbjct: 4685 R-------GLTW-EYNGVPMPKNLAGIHF-MNNGSLVILDT-SSLKEGDLELYTCKVRNR 4734 Query: 915 SSHG-ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDH 972 H +T E V VK + K E G +V+L+C+ TS ++T K + +D Sbjct: 4735 RRHSIPHLTSAFEGVPEVKTIDK-VEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDD 4793 Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 + I D GV KC+ + Sbjct: 4794 -DAIYVLPNNSLVLLNVEKYDEGVYKCVASN 4823 Score = 54.8 bits (126), Expect = 2e-05 Identities = 80/347 (23%), Positives = 136/347 (39%), Gaps = 24/347 (6%) Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 TI ++ DAG Y+ R+ +N G+ V+ V + P P I + + S+ + E Sbjct: 485 TIPELSLKDAGEYECRVISNNGNYSVKTRVETRESP-----PEIFGVRNVSVPL--GEAA 537 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA-VNEVDISDA 1464 ST VE + T +V N T+ + N + RA A V E +A Sbjct: 538 FLHCSTRSAGEVEIRW--TRYGATVFNGPNTERNPTNGTLKIHHVTRADAGVYECMARNA 595 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 + + ++ ++ P+V+ +++ E + L+C G P+P+V WY G+ L Sbjct: 596 GGMST--RKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFKGRHLLN 653 Query: 1525 --AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582 ++ Y+C A + G+ + + + P + I I+ Sbjct: 654 DYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEI----IQN 709 Query: 1583 KHKVGDEWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 K VG V+ I G P P++ W+KNG L +Y K + I K Sbjct: 710 KMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDY---IKINEGQLHIMGAKDED 766 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + Y+ N AG L V P+ E P +R VT++ Sbjct: 767 AGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQ 813 Score = 53.6 bits (123), Expect = 6e-05 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 6/79 (7%) Query: 526 TVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 TV C G P P I+W R + I I+ ++ +Q+ TL IR V P+D G + C+ Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILG-----TTLAIRNVLPDDDGFYHCI 4480 Query: 585 AKNAAGFASSTTELIVEAP 603 AK+ AG +T +LIV P Sbjct: 4481 AKSDAGQKIATRKLIVNKP 4499 Score = 53.2 bits (122), Expect = 8e-05 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 8/153 (5%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y C N G+ E + + + + PV + QK + ++ + G P P VIW Sbjct: 1713 YMCRVTNSAGKAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWK 1772 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +GN + DK + E S++RI++L S++ + A N AGT+S + ++ P+ Sbjct: 1773 IDGNDV--DKSW--LFDESLSLLRIEKL-TGKSAQISCTAENKAGTASRDFFIQNIAAPT 1827 Query: 1668 -KPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 K EG I RES TI P+ G ++T Sbjct: 1828 FKNEGD--QETIFRESETITLDCPVSLGDFQIT 1858 Score = 50.8 bits (116), Expect = 4e-04 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 K +G EC VEGYP PQ++W R ++ Y D + T++ E D+ Sbjct: 4053 KQVIEGELAVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTII--EARSLDS 4110 Query: 579 GTFTCVAKNAAGFASS--TTELIV 600 G + C A N AG A T E++V Sbjct: 4111 GIYLCSATNEAGSAQQAYTLEVLV 4134 Score = 50.0 bits (114), Expect = 7e-04 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 PI + + +T G V+ +C VE P +TWFR+ I D + Y + + TL Sbjct: 1362 PIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAI--GTDTKGYVVESD-GTL 1418 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 VI+ EDA +TC A N AG A + ++ V A Sbjct: 1419 VIQSASVEDATIYTCKASNPAGKAEANLQVTVIA 1452 Score = 48.0 bits (109), Expect = 0.003 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 4/105 (3%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E+ T E S P V +G C+V G P P + W + +P + Sbjct: 3116 EQDTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDG---EPYTSDLL 3172 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + ++ L +RE D GT+TC+A N AG + +TT++ V P Sbjct: 3173 QFST-KLSYLHLRETTLADGGTYTCIATNKAGESQTTTDVEVLVP 3216 Score = 47.6 bits (108), Expect = 0.004 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y C A N G + + P I + + HK GD+ + G+P P + WY Sbjct: 4295 YSCTAANKAGNATQKTNLNVGVAPKI-MERPRTQVVHK-GDQVTLWCEASGVPQPAITWY 4352 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K+ L N T +K SVI + S + YT +A N ++ ++ L V P Sbjct: 4353 KDNELLTNTGVDETATTKKKSVI-FSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPP 4410 Score = 47.2 bits (107), Expect = 0.005 Identities = 25/102 (24%), Positives = 45/102 (44%), Gaps = 2/102 (1%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T+ +AP +E+ R + G V C+ G P+P ITW++ ++ + + Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDET--A 4367 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +++ + P AG +TC A+N +LIV P Sbjct: 4368 TTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIP 4409 Score = 45.2 bits (102), Expect = 0.020 Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F+ K + G+ V+ C G P P ITW + +I+ S+ F++ Y L Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSK-FEIAYSH-----L 4622 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + D+G +TC+A+N+ G SST + Sbjct: 4623 KVTLNSTSDSGEYTCMAQNSVG--SSTVSAFI 4652 Score = 44.8 bits (101), Expect = 0.026 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V C+ G P+P++ W+ + + +Q+ D L IR+ D GT+ C A Sbjct: 628 VNLSCEAMGDPKPEVHWYFKGRHLLNDYKYQVGQDSK---FLYIRDATHHDEGTYECRAM 684 Query: 587 NAAGFASSTTELIVEAP 603 + AG A TT+L++ P Sbjct: 685 SQAGQARDTTDLMLATP 701 Score = 42.3 bits (95), Expect = 0.14 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%) Query: 508 MAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 +AP F E +R G+ C +G P P ITW + I+P+ D +++D Sbjct: 2475 VAPSFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPN-DRYVFFDAGR- 2532 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGF--ASSTTELIV 600 L I + D G +TC+A N+ G +T E+I+ Sbjct: 2533 -QLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVII 2568 Score = 41.1 bits (92), Expect = 0.33 Identities = 32/102 (31%), Positives = 48/102 (47%), Gaps = 25/102 (24%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 + VF KPT E VE G + + EC+++G+P+P I+W +K + Sbjct: 3294 IDVFTKPTFETHETTFNIVE---------GESAKIECKIDGHPKPTISW------LKGGR 3338 Query: 555 DFQMYYDDDNVA------TLVIREVFPEDAGTFTCVAKNAAG 590 F M DN+ TL+I + D G +TCVA N+ G Sbjct: 3339 PFNM----DNIILSPRGDTLMILKAQRFDGGLYTCVATNSYG 3376 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543 + KP KN T +EL C G P P +TW +DGK ++ +K Sbjct: 4573 IVKP-KNTTAAIGAIVELRCSAAGPPHPTITWAKDGKLIEDSKFEIA-YSHLKVTLNSTS 4630 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGI 1567 Y C+A N G S + + Sbjct: 4631 DSGEYTCMAQNSVGSSTVSAFINV 4654 Score = 39.1 bits (87), Expect = 1.3 Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T E + P ++ R +G+T CQV G P P +TW R K + F Sbjct: 3209 TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRNG---KEIEQFN---- 3261 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 L IR D G ++C+A N AG A Sbjct: 3262 ----PVLHIRNATRADEGKYSCIASNEAGTA 3288 Score = 38.3 bits (85), Expect = 2.3 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 5/94 (5%) Query: 522 PDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 P ++ +C +G P PQ+ W TA+ + + D + I V D G Sbjct: 3965 PAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ---INNVSLSDKGV 4021 Query: 581 FTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTV 613 +TC A+N AG + + +V+AP+ +G V Sbjct: 4022 YTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQV 4055 Score = 37.9 bits (84), Expect = 3.0 Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 26/201 (12%) Query: 408 FEIFYTPVEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKG 467 FE V R GDT+ + AE+ ++ V + D S Q+ K+ EK Sbjct: 2763 FEKEREEVVARVGDTMLLTCN--AESSVPLSSVYW---HAHDESVQNGVITSKYAANEKT 2817 Query: 468 WVPAQYLMDENNY---TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPD 523 +D+ + T + + +K KL V E P ++Q + PI + Sbjct: 2818 LNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIETPYFLDQQKLYPIIL---------- 2867 Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + +C G P P I + + + S + + +TLVI E G +TC Sbjct: 2868 GKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDIIG-----STLVIDNPQKEVEGRYTC 2922 Query: 584 VAKNAAGFASSTTELIVEAPL 604 +A+N AG S +++VE L Sbjct: 2923 IAENKAG--RSEKDMMVEVLL 2941 Score = 37.5 bits (83), Expect = 4.0 Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 10/106 (9%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDM 688 EG+P K V+ G ++L+C + + P + W ++++ D+ I V + Sbjct: 4747 EGVPEV--KTIDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKNDQKMLDDDAIYVLPNNS- 4803 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP 734 L + NV+K+ EG Y VA N G+A L + G+ P Sbjct: 4804 ------LVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLP 4843 >UniRef50_A2AAJ9 Cluster: Obscurin; n=10; Eutheria|Rep: Obscurin - Mus musculus (Mouse) Length = 8891 Score = 212 bits (518), Expect = 8e-53 Identities = 272/1154 (23%), Positives = 473/1154 (40%), Gaps = 100/1154 (8%) Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFAS-----STTELIVEAPLSDHGSEMTVXXXXXXXX 621 +LVI D G + C A +A AS T LI L++ E+ Sbjct: 2653 SLVIYRCETGDQGVYVCDALDAQTSASLRVQGRTYTLIFRRVLAEDAGEVKFVAENAESR 2712 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 ++ +P T + + + E +LEC+ V+ + W G E+ Sbjct: 2713 AHLR---VKELPVTLLRPLRDKIAMEKHRGVLECQ-VSRASAQVRWFKGGVELQSGPKYE 2768 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 V + +Y ++ I +V+ E TYT A N + A + E++ ++ L Sbjct: 2769 VVSDG---LYRKLV-INDVQPEDEDTYTCDAGNVKTSAQFFV-------EEQSITIVRGL 2817 Query: 742 KSMIVRQGESVILSAQV-VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKV 797 K M V + + + + RP W ++A + + DG H +T+ K Sbjct: 2818 KDMTVMEPAPAWFECETSIPSVRPP-KWLLGKTVLQAGGNVGLEQDGTVHRLTLHKTCST 2876 Query: 798 KDEGV-YTL-KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 V +T+ K+ +S + + + + P E A L Q + V Sbjct: 2877 MTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGREL-----QSV----------VLS 2921 Query: 856 VTRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 P P ++ WY+++ +SPSE +G+ EL I + + D+G Y+C AG Sbjct: 2922 CDFRPAPKAVQWYKDDTPLSPSEKFKMALEGQMAELRILRL-TPADAGVYRC----QAGS 2976 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973 + A VT++ +VT ++ LQ + EEG+ V C+ SH +W N + Sbjct: 2977 AQSSAEVTVEAREVTVIQPLQDAEAMEEGR-VCFSCELSHKDEDIEWSLNGTPLYNDSFH 3035 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 EI EG D G + S LVVK F++ L D +E+ Sbjct: 3036 EISHEGCLHTLVLKSVRQADTGTVCATSPKVSVSARLVVKGKPVVFLKALDDVSAEERGT 3095 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 L+ E++ A VVW +DG + P +KYDF + R L + + S D G Y+C + Sbjct: 3096 LTLQCEVSDPEARVVWRKDGVELGPS-DKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGS 3154 Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSN 1150 + ++V+V +L I RL+ +V +G +FE L+ D V W G + S Sbjct: 3155 KETQSKVSVHDLHVGITKRLKTVEVLEGESCSFECVLSHESPSDPAV-WTVGGKTVGGSG 3213 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 H G+K L + D L DAGE V A L + E ++ T L E Sbjct: 3214 HFHAVRQGRKYTLTVKDAALSDAGEVVFSVLGLTSKASLIIRERPVDITKPL-EDQRTTL 3272 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 D L+ E+ V W K I ++K+ L+S+ + L++RK + D EYTC Sbjct: 3273 GEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLVVRKASLKDSGEYTCET 3332 Query: 1271 LDAKSTTKLKVE--VVEFPPKIVDYEREYRIKRGSDV-TLLVDYQAFPQPNDEWIVNSKI 1327 +KST KL VE F ++ D + E ++G V T ++ A + ++ + Sbjct: 3333 EASKSTAKLCVEEKANRFTEELADLQVE---EKGRAVFTCKTEHPASVVTWRKGLLELRA 3389 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 KH PS + + LTI +E TD+ Y + A + ++ + + + Sbjct: 3390 --SGKHV-PSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQKV-RVIEDLED 3445 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 ++ SS+ C P + G +++ ++ + + E + IT Q ++ T Sbjct: 3446 TAVQEGSSAKFCCRIAPADYGP---VHWFLDKTPLHSNE---LNEIT-VQPGGYHVLTLR 3498 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + + D T+ +V ++ I S +PL ++T ED+ L C Sbjct: 3499 QLALKDSGTVYFEAGD-QRTSAALRVTEKPSIFS----RPLTDVTVTEGEDLTLVCETTT 3553 Query: 1508 VPQPKVTWYRDGKKLKTA---KATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 V V W +DGK L+ + + ++E + YKC + G +S Sbjct: 3554 VDS-SVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKC----EIGGASSSS 3608 Query: 1564 VVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 +V + PV S +D++ G + V+ + P V W + L++ +Y++ Sbjct: 3609 IVRVHALPVRFRESLKDVEVPE--GKAATLRCVLSSVAAP-VEWRHGDDVLKSSNKYSLR 3665 Query: 1623 TKEKTSVIRIKELKRSHSSKY-------TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 + + I++L+ S +Y T A+ T TSS + K+ +K + V + Sbjct: 3666 QEGAVLELVIRDLQPQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTTVTL 3725 Query: 1676 R-EISRESVTIEWK 1688 R E+++E+ +EWK Sbjct: 3726 RCELTKEA-PVEWK 3738 Score = 205 bits (501), Expect = 9e-51 Identities = 212/908 (23%), Positives = 373/908 (41%), Gaps = 67/908 (7%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ +PP F + ++Q EG+ L C++ A P + W KG E + D ++ D Sbjct: 4301 VKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLRDGG-RYSLRQD 4355 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + C L+I ++ G Y+ V G+ VL + + PP+ E LK Sbjct: 4356 GAV-CE-LQIHDLDVEDAGQYSCVC----GQEKTSAVLTV---DALPPKFTEGLKKEEAT 4406 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G V L Q+ + T+ W K K + + DG + I V+D G Y+ Sbjct: 4407 EGTMVTLRCQM--SKEATVEWRKGAKTLSDGGRYSLRQDGAMCELQICG-LAVEDAGEYS 4463 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFIN--RFQEITVKEKGTIKLVARVTRNPVP 862 G +TSA ++V+ A PP FI R QE T +GT+ + R + Sbjct: 4464 CVC----GQEKTSATLSVK------ALPPRFIEDLRSQEAT---EGTMATL-RCQMSKAA 4509 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W + +E + + + DG EL I ++ E D+G+Y CV G+ A ++ Sbjct: 4510 PVEWRKGSETLRDGDRYSLRQDGAVCELQIRDLAVE-DAGEYLCVC----GQEKTSATLS 4564 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 + F++ L +S E EG L CQ S +W K + D + Q+G Sbjct: 4565 VKALPPRFIEDL-RSQEATEGTMATLRCQMSKAAPVEWRKGSKTLRDGDRYSLRQDGAMC 4623 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C+ ++TS L VK P FI L+ E +E VA L + S Sbjct: 4624 ELQICDLAVEDTGDYSCVCGQEKTSATLSVKALPPRFIEDLRSQEAREGTVATLRCRM-S 4682 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 + A V W + E +K ++Y + G++ +L IR+ +V D EYSC+ E +A ++V Sbjct: 4683 KAAPVEWRKGSETLKDG-DRYSLRQEGNLCELQIRDLAVEDTEEYSCVCGQEKTSATLSV 4741 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 LP + I L++Q+ + + T +L+K ++V W K ++ L DG + Sbjct: 4742 KALPAKFIEDLRSQEAPESSTVTLRCKLSKKASVV-WKKGSETLRNGARYSLRQDGAVCE 4800 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 L+I D ++D GEYSC G + +A L++ P + F L + + A L E+ Sbjct: 4801 LEIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQN-LQAEEGSMASLRCELSV 4859 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + W K ++ + L++R +D EY+C TT + Sbjct: 4860 PNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTC--GSQTTSATLM 4917 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 V P + + + + G+ L + + EW S + C + + + Sbjct: 4918 VTAAPVRFLRELQAQDVDEGATARLRCELSR-EAVSVEWRKGSLQLFPCAKYQMVQEGTT 4976 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 A L + VE DAG Y + GH +++ P P K ++ Sbjct: 4977 AELLVHGVEQEDAGEYTC----DAGHTQSIARLSV-RAPKPKFKTDLQS----------T 5021 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 E E G + + + E + +W+ + + + + + + D Sbjct: 5022 EQEAGGTARLCCQLSEAEPGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTG 5081 Query: 1463 DASETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + + K + +++ P T+ + L ++ + +ED+E TC V W+ G Sbjct: 5082 EYACLVGGQKTLASLRVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGL 5141 Query: 1521 KLKTAKAT 1528 L++ + T Sbjct: 5142 PLQSNEVT 5149 Score = 194 bits (472), Expect = 3e-47 Identities = 186/734 (25%), Positives = 302/734 (41%), Gaps = 64/734 (8%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687 + +P F K + EG+ L C L A P + W KG + + + V + Sbjct: 3877 VRALPAKFKDSLKNEEATEGTTATLSCELSKAAP---VTWK-KGPKTLQSGDKYVLRQDG 3932 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 C L+I + G Y+ V + A+L + P + IE L+S Sbjct: 3933 A--VCG-LQIHGLTMADAGEYSCVCGQEKTSATLTV-------RGLPAKFIEDLRSQEAT 3982 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G + IL ++ + + W K ++ +K + DG + I + V D G Y+ Sbjct: 3983 EGATAILRCEL--SKAAPVEWRKGSETLKDGDRYTLRQDGAVCELQI-RGLAVVDTGTYS 4039 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 L + +EG+ EE TE GT+ + R + + Sbjct: 4040 LPTKFTEGLRN-------EEATE--------------------GTMATL-RCQMSKAAPV 4071 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + +E + + + DG EL I + E DSG+Y CV G+ A +++ Sbjct: 4072 EWRKGSETLRDGDRYSLRQDGAMCELQIRGLTIE-DSGEYTCVC----GQEKTSATLSVK 4126 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 F++ L +S E EG L CQ S T +W + + + Q+G Sbjct: 4127 ALPSRFIEDL-RSQEATEGTMATLRCQMSKTAPVEWKKGSETLRDGGRYSLRQDGPVCEL 4185 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G C+ ++TS L +K P FI L+ E E +A L ++ S+ Sbjct: 4186 QICDLAVEDAGEYSCVCGQEKTSATLSIKALPPRFIEDLRSQEATEGTMATLRCQM-SKA 4244 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A V W + E + +Y + G + +L I + +V D GEYSC+ E +A + V Sbjct: 4245 APVEWRKGSETLGDG-GRYSLRQNGAVCELQIHDLAVEDTGEYSCVCGQEKTSATLNVKA 4303 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 LPP I L++Q+ +G AT +++K A V W K ++ L DG +L+ Sbjct: 4304 LPPRFIEDLRSQEATEGTMATLRCQMSKA-APVEWRKGSETLRDGGRYSLRQDGAVCELQ 4362 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I+D D++DAG+YSC G K +A+LTV+ FT L + T L ++ E Sbjct: 4363 IHDLDVEDAGQYSCVCGQEKTSAVLTVDALPPKFTEGLKK-EEATEGTMVTLRCQMSKEA 4421 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 V W K + D +++L D L I +D EY+CV K++ L V+ + Sbjct: 4422 -TVEWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVEDAGEYSCVCGQEKTSATLSVKAL 4480 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 PP+ ++ R G+ TL Q EW S+ ++ D Sbjct: 4481 --PPRFIEDLRSQEATEGTMATLRC--QMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCE 4536 Query: 1345 LTIKKVENTDAGIY 1358 L I+ + DAG Y Sbjct: 4537 LQIRDLAVEDAGEY 4550 Score = 185 bits (450), Expect = 1e-44 Identities = 168/659 (25%), Positives = 288/659 (43%), Gaps = 48/659 (7%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ +PP F + ++Q EG+ L C++ A P + W KG E + D ++ + Sbjct: 4213 IKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLGDGG-RYSLRQN 4267 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 C L+I ++ G Y+ V G+ L +K PP+ IE L+S Sbjct: 4268 -GAVCE-LQIHDLAVEDTGEYSCVC----GQEKTSATLNVKA---LPPRFIEDLRSQEAT 4318 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G L Q+ + + W K ++ ++ + DG + I V+D G Y+ Sbjct: 4319 EGTMATLRCQM--SKAAPVEWRKGSETLRDGGRYSLRQDGAVCELQI-HDLDVEDAGQYS 4375 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 G +TSAV+TV+ A PP F ++ E GT+ + R + ++ Sbjct: 4376 CVC----GQEKTSAVLTVD------ALPPKFTEGLKKEEATE-GTM-VTLRCQMSKEATV 4423 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + + +S + DG EL I + E D+G+Y CV G+ A +++ Sbjct: 4424 EWRKGAKTLSDGGRYSLRQDGAMCELQICGLAVE-DAGEYSCV----CGQEKTSATLSVK 4478 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 F++ L +S E EG L CQ S +W + + D + Q+G Sbjct: 4479 ALPPRFIEDL-RSQEATEGTMATLRCQMSKAAPVEWRKGSETLRDGDRYSLRQDGAVCEL 4537 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G C+ ++TS L VK P FI L+ E E +A L ++ S+ Sbjct: 4538 QIRDLAVEDAGEYLCVCGQEKTSATLSVKALPPRFIEDLRSQEATEGTMATLRCQM-SKA 4596 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A V W + + ++ ++Y + G + +L I + +V D G+YSC+ E +A ++V Sbjct: 4597 APVEWRKGSKTLR-DGDRYSLRQDGAMCELQICDLAVEDTGDYSCVCGQEKTSATLSVKA 4655 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 LPP I L++Q+ +G AT ++K A V W K ++ + L +G +L+ Sbjct: 4656 LPPRFIEDLRSQEAREGTVATLRCRMSKA-APVEWRKGSETLKDGDRYSLRQEGNLCELQ 4714 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPD 1222 I D ++D EYSC G K +A L+V+ F LR E P ++ L ++ Sbjct: 4715 IRDLAVEDTEEYSCVCGQEKTSATLSVKALPAKFIEDLRSQE---APESSTVTLRCKL-S 4770 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 + V W K + + +++L D L IR T +D EY+C +++ L + Sbjct: 4771 KKASVVWKKGSETLRNGARYSLRQDGAVCELEIRDLTVEDTGEYSCTCGQERTSATLSI 4829 Score = 182 bits (442), Expect = 1e-43 Identities = 163/640 (25%), Positives = 268/640 (41%), Gaps = 38/640 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V EGS CR+ + W + +E + ++ + VL + + Sbjct: 3448 VQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGY---HVLTLRQLALKD 3504 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 GT A ++ A+L + K P PL + V +GE + L + Sbjct: 3505 SGTVYFEAGDQRTSAALRVTEK-------PSIFSRPLTDVTVTEGEDLTLVCETT-TVDS 3556 Query: 765 TITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ W K+ K ++ A S + ++ +D G Y + G A +S+++ V Sbjct: 3557 SVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEI----GGASSSSIVRV 3612 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 +A P F +++ V E G + V + + W ++++ S + Sbjct: 3613 ------HALPVRFRESLKDVEVPE-GKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLR 3665 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 +G +ELVI ++ + DSG Y C S G + A +T+ FV L+ E E Sbjct: 3666 QEGAVLELVIRDLQPQ-DSGQYSC----SFGDQTTSATLTVKTSSAQFVGKLRNK-EATE 3719 Query: 943 GKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 G TV L C+ + +W + + D + Q+G D G C+ Sbjct: 3720 GTTVTLRCELTKEAPVEWKKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCG 3779 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062 ++TS L VK + F+R+L+ E E D L+ E+ S+ A V W + E ++ ++ Sbjct: 3780 QEKTSATLTVKALLVHFVRRLRSKEATEGDTTTLQCEL-SKAAPVEWRKGTETLRDG-DR 3837 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122 Y ++ G + +L IR+ ++ D GEY C E +A +TV LP + L+N++ +G Sbjct: 3838 YSLKQDGAVCELQIRSLTIADAGEYLCTCGQEKTSATLTVRALPAKFKDSLKNEEATEGT 3897 Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 AT EL+K A V W K +Q + L DG L+I+ + DAGEYSC G Sbjct: 3898 TATLSCELSKA-APVTWKKGPKTLQSGDKYVLRQDGAVCGLQIHGLTMADAGEYSCVCGQ 3956 Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF 1242 K +A LTV F L T A L E+ + V W K ++D +++ Sbjct: 3957 EKTSATLTVRGLPAKFIEDLRSQEATEGAT-AILRCEL-SKAAPVEWRKGSETLKDGDRY 4014 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 TL D L IR D Y+ L K T L+ E Sbjct: 4015 TLRQDGAVCELQIRGLAVVDTGTYS---LPTKFTEGLRNE 4051 Score = 178 bits (433), Expect = 2e-42 Identities = 199/929 (21%), Positives = 362/929 (38%), Gaps = 71/929 (7%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTL 805 G S LS +V + +TW K+ K + + + ++ G + + + + K D G Y+ Sbjct: 878 GNSATLSCEVT-QAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA-DAGEYSC 935 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A G + S + V EP A+ E+ + + L V + +T Sbjct: 936 EA----GGQKLSFRLDVAEPKLVFAKGQ---QAHSEVKAEAGASATLSCEVAQAQT-EVT 987 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W+++ + +S S + G + LV+ + D+G+Y C AG R+ + Sbjct: 988 WFKDGKKLSSSSKVRMEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFRLDVAE 1042 Query: 926 EKVTFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXX 982 K+ F K Q E E G + L C+ + W+ + K++S + G Sbjct: 1043 PKMVFAKEQQARSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSR 1102 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD-FEVKEK--DVAILEVE 1039 D G C Q+ S L V E F ++ Q EVK + + A L E Sbjct: 1103 RLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQQARSEVKAEVGNSATLSCE 1162 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + +V W +DG+ + +K E G R+L ++ D GEYSC + + Sbjct: 1163 VAQAQTEVTWFKDGKKLS-SSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFR 1221 Query: 1100 VTVVELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 + V E P+++ + Q K GN AT E+ + V WFKDG ++ S+ +++ Sbjct: 1222 LDVAE--PKLVFAKEQQARSEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRM 1279 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANT 1212 G ++L + DAGEYSCE G K + L V EP + F + + A Sbjct: 1280 EASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFHLDVTEPKLVFAKEQQAHSEVKAEAGA 1339 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 A L+ E+ +VTW+K + + K + + R L++++ + D EY+C Sbjct: 1340 SATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAEG 1399 Query: 1273 AKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 K + +L V + K E + + G+ TL + A Q W + K + Sbjct: 1400 QKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSS 1458 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + S L +++ DAG Y G + + + +P ++ Sbjct: 1459 SKVRVEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDV-------AEPKLVF 1507 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 N + G S + V + + T W + + ++ + S R Sbjct: 1508 AKEQQANS--EVKAEAGASATLSCEVAQAQTEVT-WFKDGKKLSSSSKVRVEASGCSRRL 1564 Query: 1452 RAYAVNEVDISDAS-----ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 + D + S + + + E K+ ++ + E L+C Sbjct: 1565 VVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVA 1624 Query: 1507 GVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 Q +VTW++DGKKL ++K E Y C A G + S Sbjct: 1625 QA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLS 1679 Query: 1563 CVVGIQQKPVITISNEDIKQKH-KVGDEWLVTAVIE---GIPPPEVIWYKNGNKLENDKE 1618 + + + P + + E +Q H +V E +A + EV W+K+G KL + + Sbjct: 1680 FRLDVAE-PKLAFAKE--QQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSK 1736 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + + + +++ ++ + +Y+ EA Sbjct: 1737 VRVEASGCSRRLVVQQAGKADAGEYSCEA 1765 Score = 177 bits (430), Expect = 4e-42 Identities = 223/1046 (21%), Positives = 412/1046 (39%), Gaps = 85/1046 (8%) Query: 636 FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 F+K+ +A+ + G+ L C VA + ++ W G+++ + + C Sbjct: 1047 FAKEQQARSEVKAEAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRMEASG-----C 1100 Query: 693 SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L + K G Y+ A ++ L + KE Q +K+ + G S Sbjct: 1101 SRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVTEPKLVFAKEQ-QARSEVKAEV---GNS 1156 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 LS +V + +TW K+ K + + + ++ G + + + + K D G Y+ +A Sbjct: 1157 ATLSCEVA-QAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA-DAGEYSCEA- 1213 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G + S + V EP A+ E+ + + L V + +TW++ Sbjct: 1214 ---GGQKLSFRLDVAEPKLVFAKEQ---QARSEVKAEAGNSATLSCEVAQAQT-EVTWFK 1266 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + +S S + G + LV+ + D+G+Y C AG + + K+ Sbjct: 1267 DGKKLSSSSKVRMEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFHLDVTEPKL 1321 Query: 929 TFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 F K Q E E G + L C+ + W+ + K++S + G Sbjct: 1322 VFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLV 1381 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD-FEVKEKD--VAILEVEINS 1042 D G C + Q+ S L V E F ++ Q EVK + A L E+ Sbjct: 1382 VQQAGKADAGEYSCEAEGQKLSFRLDVAEPKLVFAKEQQARSEVKAEAGASATLSCEVAQ 1441 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 +V W +DG+ + +K E G R+L ++ D GEYSC + + + V Sbjct: 1442 AQTEVTWFKDGKKLS-SSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDV 1500 Query: 1103 VELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157 E P+++ + Q K G AT E+ + V WFKDG ++ S+ +++ Sbjct: 1501 AE--PKLVFAKEQQANSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEAS 1558 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAY 1215 G ++L + DAGEYSCE G K + L V EP + F + + A A Sbjct: 1559 GCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASAT 1618 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 L+ E+ +VTW+K + + K + + R L++++ + D EY+C K Sbjct: 1619 LSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKL 1678 Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + +L V + K E + + G+ TL + A Q W + K + Sbjct: 1679 SFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSSSKV 1737 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + S L +++ DAG Y +C +++ LD P K + Sbjct: 1738 RVEASGCSRRLVVQQAGKADAGEY------SCEAGGQKLSFR-LDVAEP--KLAFAKEQQ 1788 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + + E ++T+ V + Q TE K+ K +S ++ +S R Sbjct: 1789 AHSEV---KAEAGASATLSCEVAQAQ----TEVTWFKDGKKLSSS-SKVRVEASGCSRRL 1840 Query: 1455 AVNEVDISDASETT-------EYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 V + +DA E + ++++ + E K+ ++ + E L+C Sbjct: 1841 VVQQAGKADAGEYSCEAGGQKLFFRLDVAEPKLMFAKEQQAHSEVKAEAGASATLSCEVA 1900 Query: 1507 GVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 Q +VTW++DGKKL ++K E Y C A G + S Sbjct: 1901 QA-QTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLS 1955 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNI 1621 + + + ++ + + K T E EV W+K+G KL + + + Sbjct: 1956 FRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRV 2015 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEA 1647 + + ++++ ++ + +Y+ EA Sbjct: 2016 EASGCSRRLVVQQVGKADAGEYSCEA 2041 Score = 169 bits (410), Expect = 1e-39 Identities = 230/1078 (21%), Positives = 408/1078 (37%), Gaps = 78/1078 (7%) Query: 636 FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 F+K+ +A+ + G+ L C VA + ++ W G+++ + V C Sbjct: 1415 FAKEQQARSEVKAEAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----C 1468 Query: 693 SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L + K G Y+ A ++ L + KE Q +K+ G S Sbjct: 1469 SRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQ-QANSEVKA---EAGAS 1524 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 LS +V + +TW K+ K + + + ++ G + + + + K D G Y+ +A Sbjct: 1525 ATLSCEVA-QAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA- 1581 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G + S + V EP A+ E+ + + L V + +TW++ Sbjct: 1582 ---GGQKLSFRLDVAEPKLAFAKEQ---QAHSEVKAEAGASATLSCEVAQAQT-EVTWFK 1634 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + +S S + G + LV+ + D+G+Y C AG R+ + K+ Sbjct: 1635 DGKKLSSSSKVRVEASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLSFRLDVAEPKL 1689 Query: 929 TFVKHLQKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 F K Q E E G + L C+ + W+ + K++S + G Sbjct: 1690 AFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLV 1749 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD--VAILEVEINS 1042 D G C Q+ S L V E F ++ Q EVK + A L E+ Sbjct: 1750 VQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLAFAKEQQAHSEVKAEAGASATLSCEVAQ 1809 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 +V W +DG+ + +K E G R+L ++ D GEYSC + + V Sbjct: 1810 AQTEVTWFKDGKKLS-SSSKVRVEASGCSRRLVVQQAGKADAGEYSCEAGGQKLFFRLDV 1868 Query: 1103 VELPPEIITRLQNQ-----KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157 E P+++ + Q K G AT E+ + V WFKDG ++ S+ +++ Sbjct: 1869 AE--PKLMFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEAS 1926 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAY 1215 G ++L + DAGEYSCE G K + L V EP + F + + A A Sbjct: 1927 GCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASAT 1986 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 L+ E+ +VTW+K + + K + + R L++++ + D EY+C K Sbjct: 1987 LSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKL 2046 Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + +L V K E + + G+ TL + A Q W + K + Sbjct: 2047 SFRLDVADTRLMFAKEQQARTEVKAEAGNSATLSCEV-AQAQTEVTWFKDGKKLSSSSKV 2105 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + S L +++ DAG Y G + + + + S I E S Sbjct: 2106 RVEASGCSRRLVVQQAGKADAGEYSC----EAGGQKLSFRLDVAEAES-----QIPERPS 2156 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFR 1452 + E E + I+ + + W+ V+ + +L + R Sbjct: 2157 RREPLVVKEHE----TIILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTVR 2212 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 V + I E + + + KPL+ + E + L C Q + Sbjct: 2213 GAQVLDSAIYSCRVGKEGQDFPVQVEEVAAKFSKPLEPVEGELGGTVMLVCEL-SPEQAE 2271 Query: 1513 VTWYRDGKKLKTAK---ATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 V W +L+ K T E R Y C + +D TS + ++ Sbjct: 2272 VVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCESRDD----RTSARLTVK 2327 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 V+ ++ + G E V+ V WYK+G +L+ +++ + + Sbjct: 2328 VPRVVKFTSGLSAMVAEEGQEATFQCVVSP-SDAGVTWYKDGMQLQPSEKFVMVESGASR 2386 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + I L + + T+EA + ++++ V K E P + E R SVT+E Sbjct: 2387 SLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLE-PQTVEE--RTSVTLE 2441 Score = 168 bits (409), Expect = 1e-39 Identities = 170/736 (23%), Positives = 310/736 (42%), Gaps = 47/736 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ +PP F + ++Q EG+ L C++ A P + W KG E + D + ++ D Sbjct: 4477 VKALPPRFIEDLRSQEATEGTMATLRCQMSKAAP---VEWR-KGSETLRDGD-RYSLRQD 4531 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + C L+I ++ G Y V + A+L + + PP+ IE L+S Sbjct: 4532 GAV-CE-LQIRDLAVEDAGEYLCVCGQEKTSATLSV-------KALPPRFIEDLRSQEAT 4582 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G L Q+ + + W K +K ++ + DG + I V+D G Y+ Sbjct: 4583 EGTMATLRCQM--SKAAPVEWRKGSKTLRDGDRYSLRQDGAMCELQICD-LAVEDTGDYS 4639 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 G +TSA ++V+ A PP FI + +E GT+ + R + + Sbjct: 4640 CVC----GQEKTSATLSVK------ALPPRFIEDLRSQEARE-GTVATL-RCRMSKAAPV 4687 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + +E + + + +G EL I ++ E D+ +Y CV G+ A +++ Sbjct: 4688 EWRKGSETLKDGDRYSLRQEGNLCELQIRDLAVE-DTEEYSCVC----GQEKTSATLSVK 4742 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 F++ L +S E E TV L C+ S S W + + + Q+G Sbjct: 4743 ALPAKFIEDL-RSQEAPESSTVTLRCKLSKKASVVWKKGSETLRNGARYSLRQDGAVCEL 4801 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G C + TS L + F + LQ+ + +E +A L E++ Sbjct: 4802 EIRDLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAEEGSMASLRCELSVPN 4861 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A +VW + G ++ + + ++G + +L +R+ D GEYSC ++ +A + V Sbjct: 4862 AAMVWSKGGLELQGDTRR-EARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMVTA 4920 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P + LQ Q V++G A EL++ V W K ++ Q+ +G +L Sbjct: 4921 APVRFLRELQAQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTAELL 4980 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 ++ + +DAGEY+C+ G+++ A L+V P F L + A A L ++ + Sbjct: 4981 VHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDL-QSTEQEAGGTARLCCQLSEAE 5039 Query: 1225 --LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V W K+ + K+ + L+I D EY C++ K+ L+V+ Sbjct: 5040 PGTPVQWLKEGVELHVGSKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASLRVK 5099 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DS 1340 E IV + ++ DV + +W + ++ + T+ ++ D Sbjct: 5100 EPEV--TIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLADG 5157 Query: 1341 KSASLTIKKVENTDAG 1356 + L +K V DAG Sbjct: 5158 CTHVLQLKGVTLEDAG 5173 Score = 167 bits (405), Expect = 4e-39 Identities = 179/754 (23%), Positives = 300/754 (39%), Gaps = 50/754 (6%) Query: 637 SKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 +K+ K V EG EC L P W G+ + + + Y + Sbjct: 3171 TKRLKTVEVLEGESCSFECVLSHESPSDPAVWTVGGKTVGGSGHFHAVRQG--RKYTLTV 3228 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 K + E ++V+ + +ASL I + P + +PL+ GE V+LS Sbjct: 3229 KDAALSDAGEVVFSVLGLT--SKASLII-------RERPVDITKPLEDQRTTLGEDVMLS 3279 Query: 756 AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ ++ W K+ K ++ S+G T ++ +++ +KD G YT + E S+ Sbjct: 3280 CEL-SRAGTSVRWLKDGKAIRKSQKYDLLSEG-TRAVLVVRKASLKDSGEYTCETEASKS 3337 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A+ + VEE F ++ V+EKG + T +P +TW + Sbjct: 3338 TAK----LCVEEKANR------FTEELADLQVEEKGRAVFTCK-TEHPASVVTWRKGLLE 3386 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + S + +G ++L I N DS Y C G++ AR+ + +KV ++ Sbjct: 3387 LRASGKHVPSQEGLTLKLTI-NALERTDSDTYTC----DIGQARTQARLLVHGQKVRVIE 3441 Query: 933 HLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREI-IQEGRXXXXXXXXX 989 L+ + +EG + C+ + W+ +K + + EI +Q G Sbjct: 3442 DLEDT-AVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVLTLRQL 3500 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 D G + DQ TS L V E F R L D V E + L E + + V W Sbjct: 3501 ALKDSGTVYFEAGDQRTSAALRVTEKPSIFSRPLTDVTVTEGEDLTLVCETTTVDSSVRW 3560 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 +DG+ ++P + G +L I T+ D G Y C + S ++ V V LP Sbjct: 3561 TKDGKTLRPSA-RCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVHALPVRF 3619 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 L++ +V +G AT L+ A V W ++ SN L +G +L I D Sbjct: 3620 RESLKDVEVPEGKAATLRCVLSSVAAPVEWRHGDDVLKSSNKYSLRQEGAVLELVIRDLQ 3679 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 D+G+YSC G+ +A LTV+ S F +L T L E+ E V W Sbjct: 3680 PQDSGQYSCSFGDQTTSATLTVKTSSAQFVGKLRNKEATEGTT-VTLRCELTKEA-PVEW 3737 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 K + + +K++L D L I D EY+CV K++ L V+ + Sbjct: 3738 KKGTETLRNGDKYSLKQDGAVCELQICSLLVADAGEYSCVCGQEKTSATLTVKAL----- 3792 Query: 1290 IVDYEREYRIKRGSD-VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 +V + R R K ++ T + + EW ++ ++ D L I+ Sbjct: 3793 LVHFVRRLRSKEATEGDTTTLQCELSKAAPVEWRKGTETLRDGDRYSLKQDGAVCELQIR 3852 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + DAG Y CG +T+ P+ Sbjct: 3853 SLTIADAGEYLC----TCGQEKTSATLTVRALPA 3882 Score = 164 bits (398), Expect = 3e-38 Identities = 143/655 (21%), Positives = 276/655 (42%), Gaps = 38/655 (5%) Query: 636 FSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 F+K+ +A+ + G+ L C VA + ++ W G+++ + V C Sbjct: 2059 FAKEQQARTEVKAEAGNSATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----C 2112 Query: 693 SV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L + K G Y+ A G L L + E + P+ + ++V++ E+ Sbjct: 2113 SRRLVVQQAGKADAGEYSCEA----GGQKLSFRLDVAEAESQIPERPSRREPLVVKEHET 2168 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 +IL+A + +TW K+ + K S GDTH++T+ + +V D +Y+ + Sbjct: 2169 IILTATIAAPSVAAVTWLKDGVEIRRSKRHEATSLGDTHTLTV-RGAQVLDSAIYSCRV- 2226 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 EG + VEE + ++P + + + GT+ LV ++ + W Sbjct: 2227 GKEG---QDFPVQVEEVAAKFSKP------LEPVEGELGGTVMLVCELSPEQA-EVVWRC 2276 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N + P + +G L ++ + E D+ +Y C + + ++S AR+T+ V +V Sbjct: 2277 GNTQLRPGKRFQMTSEGPRRTLTVSGL-REDDAEEYVCESRDD--RTS--ARLTVKVPRV 2331 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + EEG+ +C S + WY + ++ + +++ G Sbjct: 2332 VKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPSEKFVMVESGASRSLTIL 2391 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G + + +S L V+E F +KL+ V+E+ LEVE+ +V Sbjct: 2392 GLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVEERTSVTLEVELTRPWPEV 2451 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W R+ ++ P +N + G L +R+ D G + C D+ A++ V Sbjct: 2452 KWTRNAAVLTPSEN-VEIRAEGARHCLVLRSVGFADRGFFGCETPDDKTQAKLNVEMRQV 2510 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 ++ LQ + + A+ ++EL+ + W +DG +Q L + G L + Sbjct: 2511 RLVRGLQEVEAKEQGTASMDVELSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILTLSA 2570 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 D+G + +A L V E ++FT R+ + ++ L E+ +DV Sbjct: 2571 LQPQDSGLVAFRAEGVHTSARLIVTELPVSFT-RVLQDVVATQKEKVTLECEL-SRPVDV 2628 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 W K + + +++ R+L+I +C DQ Y C LDA+++ L+V+ Sbjct: 2629 RWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGVYVCDALDAQTSASLRVQ 2683 Score = 149 bits (362), Expect = 6e-34 Identities = 197/893 (22%), Positives = 344/893 (38%), Gaps = 60/893 (6%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704 + G+ L C VA + ++ W G+++ + V CS L + K Sbjct: 1612 EAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----CSRRLVVQQAGKAD 1665 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y+ A ++ L + + K + Q +K+ G S LS +V + Sbjct: 1666 AGEYSCEAGGQKLSFRLDVA-EPKLAFAKEQQAHSEVKA---EAGASATLSCEVA-QAQT 1720 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 +TW K+ K + + + ++ G + + + + K D G Y+ +A G + S + Sbjct: 1721 EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA----GGQKLSFRLD 1775 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V EP A+ E+ + + L V + +TW+++ + +S S + Sbjct: 1776 VAEPKLAFAKEQ---QAHSEVKAEAGASATLSCEVAQAQT-EVTWFKDGKKLSSSSKVRV 1831 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET- 940 G + LV+ + D+G+Y C AG R+ + K+ F K Q E Sbjct: 1832 EASGCSRRLVVQQA-GKADAGEYSC----EAGGQKLFFRLDVAEPKLMFAKEQQAHSEVK 1886 Query: 941 -EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 E G + L C+ + W+ + K++S + G D G Sbjct: 1887 AEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKADAGEYS 1946 Query: 999 CIVKDQETSTMLVVKETIPEFIRKLQDF-EVKEKD--VAILEVEINSETADVVWERDGEI 1055 C Q+ S L V E F ++ Q EVK + A L E+ +V W +DG+ Sbjct: 1947 CEAGGQKLSFRLDVAEPKLVFAKEQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGKK 2006 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115 + +K E G R+L ++ D GEYSC R + + + V + Q Sbjct: 2007 LS-SSSKVRVEASGCSRRLVVQQVGKADAGEYSCEARGQKLSFRLDVADTRLMFAKEQQA 2065 Query: 1116 Q---KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 + K GN AT E+ + V WFKDG ++ S+ +++ G ++L + D Sbjct: 2066 RTEVKAEAGNSATLSCEVAQAQTEVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKAD 2125 Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETL-DVTW 1229 AGEYSCE G K + L V E R E ++V + LT I ++ VTW Sbjct: 2126 AGEYSCEAGGQKLSFRLDVAEAESQIPERPSRREPLVVKEHETIILTATIAAPSVAAVTW 2185 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 K I +++ S TL +R D Y+C + K V+V E K Sbjct: 2186 LKDGVEIRRSKRHEATSLGDTHTLTVRGAQVLDSAIYSCRV--GKEGQDFPVQVEEVAAK 2243 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 + G V L+ + Q W + ++ K + + + +LT+ Sbjct: 2244 FSKPLEPVEGELGGTVMLVCELSP-EQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSG 2302 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 + DA Y ++ A + + V + K + + E + C P + G Sbjct: 2303 LREDDAEEYVCESRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAG- 2361 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +Y Q + +++ V++ +I L + + A E S A+ Sbjct: 2362 --VTWYKDGMQLQPSEKFVMVESGASRSLTILGLTLEDAGQVTVEA--EGASSSAALRVR 2417 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 V+ + K++ TVE+ T ++ELT P P+V W R+ L Sbjct: 2418 EAPVLFKKKLEPQTVEE-----RTSVTLEVELT-----RPWPEVKWTRNAAVL 2460 Score = 135 bits (327), Expect = 1e-29 Identities = 182/828 (21%), Positives = 322/828 (38%), Gaps = 95/828 (11%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S AP F+ + + G CQ+ G P P ++W + ++ F++ D D V Sbjct: 6 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGD-VY 64 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 L I ++ D+G + C A+NA G A + L V+ SE T Sbjct: 65 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLRVD-------SEGTCAEQA--------- 108 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 P F +P + V EG+D CR+ P+P ++W G + P + V +E Sbjct: 109 -------PHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEE 161 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPP--------- 735 H S L+I + + GTY V A N G A+ +V+ PP Sbjct: 162 --HGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLA 219 Query: 736 -----------QVIEP------LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--- 775 + I P ++ V +G+ LS V G P+P W K+ + V Sbjct: 220 HLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEG 279 Query: 776 -KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 + + + + + + IL K+ D G+YT A N G +S ++ V EPT Sbjct: 280 RRHVVYEDEQENFVLKILFCKQ-SDRGLYTCTASNLVGQTYSSVLVVVREPTVP------ 332 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 F R Q++ V+EK + V + P W++ + S +G L + N Sbjct: 333 FKKRLQDLEVREKESATFQCEVAQ-PATEAAWFKEETRLWASAKYDIEEEGTERRLTVRN 391 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTS 953 V ++ D Y C +++ G+R ++ + + L + G T I + + Sbjct: 392 VSAD-DDAVYIC-------ETTEGSRTVAELSVQGNLTRKLPRKTAVRTGDTAIFWVELA 443 Query: 954 HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012 +W N++E+ I EG D+G + + T+T V Sbjct: 444 VPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCV 503 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKK-NKYDFEK--- 1067 + D VK K + + + ++ D DG +++ +K Y + + Sbjct: 504 SAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHE 563 Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE--------IITRLQNQKVN 1119 G + T V +EG++ + + + +E P + T L+ + Sbjct: 564 AGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAV 623 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 +G + TF ++LT + WF DG ++ S+ + D + L I + G Sbjct: 624 EGGEVTFSVDLTVASS-GEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKF 682 Query: 1180 VGNSKCTAILTVEEPSINF-TLRLPEF----ILVPANTDAYLTVEIPDETLDVTWYKKKS 1234 V N T+I V ++ + +LP +L + +A L E+ D+ VTW K Sbjct: 683 VANGIETSIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGR 742 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + K+ + +R L++R +DD Y CV +++ +L V+ Sbjct: 743 ELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQ 790 Score = 130 bits (315), Expect = 3e-28 Identities = 161/721 (22%), Positives = 278/721 (38%), Gaps = 41/721 (5%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704 + G+ L C VA + ++ W G+++ + V CS L + V K Sbjct: 1980 EAGASATLSCE-VAQAQTEVTWFKDGKKLSSSSKVRVEASG-----CSRRLVVQQVGKAD 2033 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y+ A ++ L + KE Q +K+ G S LS +V + Sbjct: 2034 AGEYSCEARGQKLSFRLDVADTRLMFAKEQ-QARTEVKA---EAGNSATLSCEVA-QAQT 2088 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 +TW K+ K + + + ++ G + + + + K D G Y+ +A G + S + Sbjct: 2089 EVTWFKDGKKLSSSSKVRVEASGCSRRLVVQQAGKA-DAGEYSCEA----GGQKLSFRLD 2143 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V E + E P +R + + VKE TI L A + V ++TW ++ I S+ Sbjct: 2144 VAEAESQIPERP---SRREPLVVKEHETIILTATIAAPSVAAVTWLKDGVEIRRSKRHEA 2200 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 G+ L + +DS Y C GK V ++ F K L+ E E Sbjct: 2201 TSLGDTHTLTVRGAQV-LDSAIYSC----RVGKEGQDFPVQVEEVAAKFSKPLEP-VEGE 2254 Query: 942 EGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G TV+L C+ S W ++ ++ EG D C Sbjct: 2255 LGGTVMLVCELSPEQAEVVWRCGNTQLRPGKRFQMTSEGPRRTLTVSGLREDDAEEYVCE 2314 Query: 1001 VKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 +D TS L VK + +F L +E A + ++ A V W +DG ++P Sbjct: 2315 SRDDRTSARLTVKVPRVVKFTSGLSAMVAEEGQEATFQCVVSPSDAGVTWYKDGMQLQPS 2374 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 + K+ + G R L I ++ D G+ + S +A + V E P +L+ Q V Sbjct: 2375 E-KFVMVESGASRSLTILGLTLEDAGQVTVEAEGASSSAALRVREAPVLFKKKLEPQTVE 2433 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 + T E+ELT+ V+W ++ + + S ++++ +G + L + D G + CE Sbjct: 2434 ERTSVTLEVELTRPWPEVKWTRNAAVLTPSENVEIRAEGARHCLVLRSVGFADRGFFGCE 2493 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 + K A L VE + L E T A + VE+ ++ +W + ++ Sbjct: 2494 TPDDKTQAKLNVEMRQVRLVRGLQEVEAKEQGT-ASMDVELSHAEVEGSWTRDGLRLQPG 2552 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKIVDYEREYR 1298 K L L + D V A+ T ++ V E P ++ Sbjct: 2553 PKCHLAVQGPVHILTLSALQPQDS---GLVAFRAEGVHTSARLIVTELPVSFTRVLQDVV 2609 Query: 1299 IKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 + VTL + +P D W+ + ++ K SL I + E D G+ Sbjct: 2610 ATQKEKVTLECE---LSRPVDVRWLKDGVELRAGKAIGIVAQGTCRSLVIYRCETGDQGV 2666 Query: 1358 Y 1358 Y Sbjct: 2667 Y 2667 Score = 128 bits (310), Expect = 1e-27 Identities = 192/880 (21%), Positives = 336/880 (38%), Gaps = 85/880 (9%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 + L PK + +V C P+ + W++ + PS+ F+M + +A L I Sbjct: 2902 VLTRPLEPKAGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMALEGQ-MAELRI 2959 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630 + P DAG + C AG A S+ E+ VEA E+TV Sbjct: 2960 LRLTPADAGVYRC----QAGSAQSSAEVTVEA------REVTV----------------- 2992 Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 I P A+ ++EG + C L + + DI W G + D ++ E +H Sbjct: 2993 -IQPL----QDAEAMEEGR-VCFSCEL-SHKDEDIEWSLNGTPLYNDSFHEISHEGCLH- 3044 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L + +V+ Q T TV A + + S +V+K K P ++ L + + Sbjct: 3045 ---TLVLKSVR--QADTGTVCATSPKVSVSARLVVKGK-----PVVFLKALDDVSAEERG 3094 Query: 751 SVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 ++ L + V +P + W K+ P +T+ +D G+YT + Sbjct: 3095 TLTLQCE-VSDPEARVVWRKDGVELGPSDKYDFLHKAGARGLTV-HDLSHEDAGLYTCQV 3152 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITW 866 G ET + ++V + R + + V E + ++ +P W Sbjct: 3153 ----GSKETQSKVSVHDLHVG------ITKRLKTVEVLEGESCSFECVLSHESPSDPAVW 3202 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + + S G L + + + D+G+ V + G +S A + I Sbjct: 3203 TVGGKTVGGSGHFHAVRQGRKYTLTVKDA-ALSDAGE---VVFSVLGLTSK-ASLIIRER 3257 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 V K L+ T G+ V+L C+ S S +W + K I +++ EG Sbjct: 3258 PVDITKPLE-DQRTTLGEDVMLSCELSRAGTSVRWLKDGKAIRKSQKYDLLSEGTRAVLV 3316 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G C + +++ L V+E F +L D +V+EK A+ + + Sbjct: 3317 VRKASLKDSGEYTCETEASKSTAKLCVEEKANRFTEELADLQVEEKGRAVFTCKTEHPAS 3376 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 V W R G + K+ + G KL I D Y+C + A + V Sbjct: 3377 VVTW-RKGLLELRASGKHVPSQEGLTLKLTINALERTDSDTYTCDIGQARTQARLLVHGQ 3435 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTID-GKKQKL 1163 +I L++ V +G+ A F + D V WF D + + + ++T+ G L Sbjct: 3436 KVRVIEDLEDTAVQEGSSAKFCCRIAPADYGPVHWFLDKTPLHSNELNEITVQPGGYHVL 3495 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 + L D+G E G+ + +A L V E+PSI F+ L + + V D L E Sbjct: 3496 TLRQLALKDSGTVYFEAGDQRTSAALRVTEKPSI-FSRPLTD-VTVTEGEDLTLVCETTT 3553 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V W K + + + L + + L+I T D Y C + A S++ ++V Sbjct: 3554 VDSSVRWTKDGKTLRPSARCQLSHEGCQAQLLITATTPQDGGRYKCEIGGASSSSIVRVH 3613 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 + P + + ++ + G TL + P EW ++K + Sbjct: 3614 AL--PVRFRESLKDVEVPEGKAATLRCVLSSVAAP-VEWRHGDDVLKSSNKYSLRQEGAV 3670 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 L I+ ++ D+G Y +C D + T+ K S Sbjct: 3671 LELVIRDLQPQDSGQY------SCSFGDQTTSATLTVKTS 3704 Score = 118 bits (283), Expect = 2e-24 Identities = 129/574 (22%), Positives = 243/574 (42%), Gaps = 47/574 (8%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPD-ENISVAIES 686 ++ +PP F + ++Q EG+ L CR+ A P + W KG E + D + S+ E Sbjct: 4653 VKALPPRFIEDLRSQEAREGTVATLRCRMSKAAP---VEWR-KGSETLKDGDRYSLRQEG 4708 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 ++ C L+I ++ Y+ V + A+L + + P + IE L+S Sbjct: 4709 NL---CE-LQIRDLAVEDTEEYSCVCGQEKTSATLSV-------KALPAKFIEDLRSQEA 4757 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVY 803 + +V L ++ + + ++ W K ++ ++ + DG + I + V+D G Y Sbjct: 4758 PESSTVTLRCKL--SKKASVVWKKGSETLRNGARYSLRQDGAVCELEI-RDLTVEDTGEY 4814 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + G TSA +++ P +P Q + +E L ++ P + Sbjct: 4815 SCTC----GQERTSATLSIMAPQVVFQQP------LQNLQAEEGSMASLRCELSV-PNAA 4863 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W + + G EL++ ++ E D+G+Y C + G + A + + Sbjct: 4864 MVWSKGGLELQGDTRREARQQGCVAELLLRDLRRE-DAGEYSC----TCGSQTTSATLMV 4918 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXX 982 V F++ LQ + + +EG T L C+ S VS +W ++ +++QEG Sbjct: 4919 TAAPVRFLRELQ-AQDVDEGATARLRCELSREAVSVEWRKGSLQLFPCAKYQMVQEGTTA 4977 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C ++ L V+ P+F LQ E + A L +++ Sbjct: 4978 ELLVHGVEQEDAGEYTCDAGHTQSIARLSVRAPKPKFKTDLQSTEQEAGGTARLCCQLSE 5037 Query: 1043 ET--ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 V W ++G + +KY+ ++G + +L I D GEY+C++ + A + Sbjct: 5038 AEPGTPVQWLKEGVELHVG-SKYEMRRQGAVCELLIHGLEAKDTGEYACLVGGQKTLASL 5096 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--D 1157 V E I+ L + +V F ++++ A V+W G +Q + ++ + D Sbjct: 5097 RVKEPEVTIVRGLVDMEVQADEDVEFTCKVSQAGATDVQWHLQGLPLQSNEVTEVAVLAD 5156 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 G L++ L+DAG S VG +A LTV Sbjct: 5157 GCTHVLQLKGVTLEDAGTVSFHVGGLSSSAQLTV 5190 Score = 112 bits (269), Expect = 1e-22 Identities = 113/544 (20%), Positives = 206/544 (37%), Gaps = 33/544 (6%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 K GN AT E+T+ V WFKDG ++ S+ +++ G ++L + DAGEY Sbjct: 874 KAEAGNSATLSCEVTQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEY 933 Query: 1177 SCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234 SCE G K + L V EP + F + + A A L+ E+ +VTW+K Sbjct: 934 SCEAGGQKLSFRLDVAEPKLVFAKGQQAHSEVKAEAGASATLSCEVAQAQTEVTWFKDGK 993 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV-EVVEFPPKIVDY 1293 + + K + + R L++++ + D EY+C K + +L V E K Sbjct: 994 KLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKLSFRLDVAEPKMVFAKEQQA 1053 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 E + + G+ TL + A Q W + K + + S L +++ Sbjct: 1054 RSEVKAEAGASATLSCEV-AQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKA 1112 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 DAG Y E ++VT +P ++ + GNS + Sbjct: 1113 DAGEYS--CEAGGQKLSFRLDVT---------EPKLVFAKEQQARS--EVKAEVGNSATL 1159 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS-----ETT 1468 V + + T W + + ++ + S R + D + S + Sbjct: 1160 SCEVAQAQTEVT-WFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEYSCEAGGQKL 1218 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKA 1527 + + E K+ ++ + E L+C Q +VTW++DGKKL ++K Sbjct: 1219 SFRLDVAEPKLVFAKEQQARSEVKAEAGNSATLSCEVAQA-QTEVTWFKDGKKLSSSSKV 1277 Query: 1528 TYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKH 1584 E Y C A G + S + + + ++ + + Sbjct: 1278 RMEASGCSRRLVVQQAGKADAGEYSCEA----GGQKLSFHLDVTEPKLVFAKEQQAHSEV 1333 Query: 1585 KVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 K T E EV W+K+G KL + + + + + +++ ++ + +Y Sbjct: 1334 KAEAGASATLSCEVAQAQTEVTWFKDGKKLSSSSKVRMEASGCSRRLVVQQAGKADAGEY 1393 Query: 1644 TIEA 1647 + EA Sbjct: 1394 SCEA 1397 Score = 109 bits (261), Expect = 1e-21 Identities = 87/368 (23%), Positives = 158/368 (42%), Gaps = 36/368 (9%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 +P+ + P + AP+F+ +L+ + DG + F+C V G P P + WF+ +++ Sbjct: 6053 VPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDD 6112 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH--GSEMT 612 + + D L+I V P D G + C+A+N+ G +S+ EL VE +D+ ++ T Sbjct: 6113 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDYDTAADAT 6172 Query: 613 VXXXXXXXXXXXXADILEGIP------PTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDI 665 + EG P ++ K V G+ + + ++ P P + Sbjct: 6173 ETSSYFSAQGYLSSREQEGTESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKL 6232 Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W G+ + ++I + + +H L+I +V + G Y N G A L Sbjct: 6233 YWFKDGQPLTTSDHIRMTDKKTLH----TLEIVSVTREDSGQYAAYISNAVGAAYSSARL 6288 Query: 726 KIK-TGEKE------------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN- 771 ++ E E PP+++E V++G S+ S +V G+P P++ W K Sbjct: 6289 LVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEE 6348 Query: 772 -NKPVKALPTKSDGDT-------HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 K V + + G T HS+ +L + + +G YT A N G A SA + + Sbjct: 6349 AEKGVLWIGPDTPGYTMASSSKQHSLVLLDVGR-QHQGTYTCIATNPAGQALCSASLHIS 6407 Query: 824 EPTEENAE 831 +E + Sbjct: 6408 GLAKEEEQ 6415 Score = 99.5 bits (237), Expect = 9e-19 Identities = 176/932 (18%), Positives = 359/932 (38%), Gaps = 87/932 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F KK + Q V+E + + LE L P P++ W + P EN+ + E H C Sbjct: 2420 PVLFKKKLEPQTVEERTSVTLEVELTR-PWPEVKWTRNAAVLTPSENVEIRAEGARH--C 2476 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 VL+ +V G + + + +A L + E +++ L+ + ++ + Sbjct: 2477 LVLR--SVGFADRGFFGCETPDDKTQAKLNV-------EMRQVRLVRGLQEVEAKEQGTA 2527 Query: 753 ILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + + + + +W ++ +P G H +T L + +D G+ +A Sbjct: 2528 SMDVE-LSHAEVEGSWTRDGLRLQPGPKCHLAVQGPVHILT-LSALQPQDSGLVAFRA-- 2583 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 EG+ ++ +I E P F Q++ +K + L ++R PV + W ++ Sbjct: 2584 -EGVHTSARLIVTELPVS-------FTRVLQDVVATQKEKVTLECELSR-PV-DVRWLKD 2633 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC---VASNSAGKSSHGARVTI--- 923 + + I G LVI ++ D G Y C A SA G T+ Sbjct: 2634 GVELRAGKAIGIVAQGTCRSLVIYRCETG-DQGVYVCDALDAQTSASLRVQGRTYTLIFR 2692 Query: 924 -----DVEKVTFV-------KHLQ------------KSYETEEGKTVILECQTSH-TVST 958 D +V FV HL+ + E +LECQ S + Sbjct: 2693 RVLAEDAGEVKFVAENAESRAHLRVKELPVTLLRPLRDKIAMEKHRGVLECQVSRASAQV 2752 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018 +W+ E+ E++ +G D C + +TS V+E Sbjct: 2753 RWFKGGVELQSGPKYEVVSDGLYRKLVINDVQPEDEDTYTCDAGNVKTSAQFFVEEQSIT 2812 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 +R L+D V E A E E + + G+ + E+ G + +L + Sbjct: 2813 IVRGLKDMTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQDGTVHRLTLHK 2872 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138 T G + +A++ V ++P + L+ + + + V+ Sbjct: 2873 TCSTMTGPVHFTIGKSRSSAQLVVSDIPVVLTRPLEPKAGRELQSVVLSCDFRPAPKAVQ 2932 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF 1198 W+KD + + S ++ ++G+ +L+I DAG Y C+ G+++ +A +TVE + Sbjct: 2933 WYKDDTPLSPSEKFKMALEGQMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTV 2992 Query: 1199 TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L + + + + E+ + D+ W + + + + + TL+++ Sbjct: 2993 IQPLQDAEAMEEGRVCF-SCELSHKDEDIEWSLNGTPLYNDSFHEISHEGCLHTLVLKSV 3051 Query: 1259 TEDDQ---CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315 + D C T + + +K + V F + D E +RG+ +TL + + P Sbjct: 3052 RQADTGTVCA-TSPKVSVSARLVVKGKPVVFLKALDDVSAE---ERGT-LTLQCEV-SDP 3105 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 + W + + + + LT+ + + DAG+Y ++ + + V ++ Sbjct: 3106 EARVVWRKDGVELGPSDKYDFLHKAGARGLTVHDLSHEDAGLYTCQVGSKETQSKVSVHD 3165 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKNIT 1434 + +LE +S S C E+ + + + V + + + + +V+ Sbjct: 3166 LHVGITKRLKTVEVLEGESCSFE-CVLSHESPSDPAV--WTVGGKTVGGSGHFHAVRQGR 3222 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 K ++++ + + EV S T++ +I+E + + KPL++ T Sbjct: 3223 KYTLTVKDAALSDA--------GEVVFSVLGLTSKASLIIRERPVD---ITKPLEDQRTT 3271 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 ED+ L+C V W +DGK ++ ++ Sbjct: 3272 LGEDVMLSCELSRA-GTSVRWLKDGKAIRKSQ 3302 Score = 85.4 bits (202), Expect = 2e-14 Identities = 84/330 (25%), Positives = 137/330 (41%), Gaps = 17/330 (5%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 L V + T EQ AP F+ + +G+ F C+V G P+P ++W + + P Sbjct: 96 LRVDSEGTCAEQ--APHFLLRPTSIRVREGADATFRCRVGGSPQPAVSWSKDGRRLGPPD 153 Query: 555 DFQMYYDDDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT- 612 + ++ ++ L IR P D GT+ A+N G AS+ L+V++ G T Sbjct: 154 APHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTS 213 Query: 613 VXXXXXXXXXXXXADILEGIPPT-FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671 A EGIPP+ + V EG L C + P+P+ W K Sbjct: 214 TATLLAHLQQRREAMRAEGIPPSPPGAGTRTCTVTEGKHARLSCFVTGEPKPETVWK-KD 272 Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 ++V + V E + + VLKI K+ G YT A N G+ +++ ++ E Sbjct: 273 GQLVTEGRRHVVYEDEQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR--E 328 Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHS 788 P + L+ + VR+ ES + V P W K + A + +G Sbjct: 329 PTVP-FKKRLQDLEVREKESATFQCE-VAQPATEAAWFKEETRLWASAKYDIEEEGTERR 386 Query: 789 ITILKPKKVKDEGVYTLK-AENSEGIAETS 817 +T+ + D+ VY + E S +AE S Sbjct: 387 LTV-RNVSADDDAVYICETTEGSRTVAELS 415 Score = 83.8 bits (198), Expect = 5e-14 Identities = 71/294 (24%), Positives = 130/294 (44%), Gaps = 14/294 (4%) Query: 1046 DVVWERDGEIIKPKKNK--YDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEV 1100 + VW++DG+++ + Y+ E+ + K+ S D G Y+C L ++ ++ + Sbjct: 266 ETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQS--DRGLYTCTASNLVGQTYSSVL 323 Query: 1101 TVVELPP-EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 VV P RLQ+ +V + ATF+ E+ + WFK+ + + S + +G Sbjct: 324 VVVREPTVPFKKRLQDLEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGT 383 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 +++L + + DD Y CE S+ A L+V+ N T +LP V A V Sbjct: 384 ERRLTVRNVSADDDAVYICETTEGSRTVAELSVQG---NLTRKLPRKTAVRTGDTAIFWV 440 Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 E+ V W + + + + + ++ TL I +CT +D E V ++TT+ Sbjct: 441 ELAVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQ 500 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 V PP + + K S VTL + A P + ++ +++K K Sbjct: 501 FCVSAPRRPPLYPPADPVVKAKTESSVTL--SWSAPPHGDRPVTIDGYVLEKRK 552 Score = 80.2 bits (189), Expect = 6e-13 Identities = 58/227 (25%), Positives = 95/227 (41%), Gaps = 11/227 (4%) Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 +V+K+ TV+ N + I ++ PP+ E L GE+V L+ +V Sbjct: 6918 SVRKYLLQARTVIIKNSWVKEICGIQQRLAQPVWRPPEFEEELADCTAELGETVKLACRV 6977 Query: 759 VGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G P+P ++W K+ KPV+ P D D IL D G Y A ++ G A Sbjct: 6978 TGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNAS 7037 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 T I V+ PP F+N+ + E ++ V P P I WY++ +++P Sbjct: 7038 TLGKILVQ-------VPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAP 7090 Query: 876 SETITQ-NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 N + +++ S+ D G Y+C N G + G + Sbjct: 7091 GNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGSTRGGGEL 7137 Score = 78.2 bits (184), Expect = 2e-12 Identities = 84/400 (21%), Positives = 160/400 (40%), Gaps = 29/400 (7%) Query: 1139 WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEE 1193 W KDG + + H+ + + LKI C D G Y+C VG + + ++ V E Sbjct: 269 WKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 328 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 P++ F RL + + V A E+ + W+K+++ + + K+ + + +R L Sbjct: 329 PTVPFKKRLQD-LEVREKESATFQCEVAQPATEAAWFKEETRLWASAKYDIEEEGTERRL 387 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 +R + DD Y C + T +L V+ K+ R+ ++ G V+ Sbjct: 388 TVRNVSADDDAVYICETTEGSRTVAELSVQG-NLTRKL---PRKTAVRTGDTAIFWVEL- 442 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 A P+ W+ N + + + + +LTI + D G + C + Sbjct: 443 AVPEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAF-VSGGC-RTTTQ 500 Query: 1373 MNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNS-TIIYYVVEYQEIDTTEWIS 1429 V+ +P PP P + SS+ + W P + TI YV+E +++ W Sbjct: 501 FCVSAPRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSR 560 Query: 1430 VKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 + T+ +I + ++FR A+N E ++ +++P K Sbjct: 561 CHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPL--K 618 Query: 1487 PLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 ++ + E ++LT G W+ DG+ LK + Sbjct: 619 AVEAVEGGEVTFSVDLTVASSG------EWFLDGEALKAS 652 Score = 67.7 bits (158), Expect = 3e-09 Identities = 48/169 (28%), Positives = 75/169 (44%), Gaps = 8/169 (4%) Query: 1585 KVGDEWLVTAVI-EGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + T ++ E +P E WY NG ++ +D ++ +TT + + + H+ + Sbjct: 5386 KAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGE 5445 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 T A + ++ + V L + D P E V+ R S SVT+ W P+ DGG L Y Sbjct: 5446 VTFAARDAVASARLSV-LALPDPPEDAE--VVGR--SDHSVTLSWVAPMSDGGGGLCGYR 5500 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 +E E +W D+ E + L Y FRV A P G E Sbjct: 5501 VEMKEASTGQWQLCHDLVPGPEC-VVDDLVPGKTYRFRVAAVGPAGAGE 5548 Score = 66.1 bits (154), Expect = 1e-08 Identities = 58/216 (26%), Positives = 96/216 (44%), Gaps = 22/216 (10%) Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALP--TKSDG 784 ++ E + PQV+E LK + V G + +V G P P + W K+ +P+ +D Sbjct: 6193 ESDEGQLPQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDK 6252 Query: 785 DT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE----------ENAEPP 833 T H++ I+ + +D G Y N+ G A +SA + V P+E E PP Sbjct: 6253 KTLHTLEIVSVTR-EDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPP 6311 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-----IISP-SETITQNFDGEN 887 + +F VK +I +V +P PS+ W + I P + T + Sbjct: 6312 RILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQ 6371 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 LV+ +V + G Y C+A+N AG++ A + I Sbjct: 6372 HSLVLLDVGRQ-HQGTYTCIATNPAGQALCSASLHI 6406 Score = 64.5 bits (150), Expect = 3e-08 Identities = 43/180 (23%), Positives = 73/180 (40%), Gaps = 9/180 (5%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXX 1536 P E+ L + T E E ++L C G P+P V+WY+DGK ++ + Sbjct: 6954 PEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLI 7013 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C A + G T + +Q P N+ G++ +T + Sbjct: 7014 LDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPP--RFVNKVRATPFVEGEDAQITCTV 7071 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTS 1654 EG P P++ WYK+G L Y + + ++ V+ I+ + Y E N G++ Sbjct: 7072 EGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLGST 7131 Score = 60.9 bits (141), Expect = 4e-07 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568 P FV K+R +G Q C VEG P PQI W++ ++ P ++M + V L Sbjct: 7048 PRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVL 7107 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 VI+ ED G + C N G EL +++P Sbjct: 7108 VIQAASKEDLGHYECELVNRLGSTRGGGELYMQSP 7142 Score = 60.5 bits (140), Expect = 5e-07 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Query: 499 EKPTSE--EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-----IK 551 EKP S+ E+ + P +EK PK GS++ F +VEG+P P + W ++ A I Sbjct: 6298 EKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIG 6357 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610 P +LV+ +V + GT+TC+A N AG A + L + + E Sbjct: 6358 PDTPGYTMASSSKQHSLVLLDVGRQHQGTYTCIATNPAGQALCSASLHISGLAKEEEQE 6416 Score = 59.7 bits (138), Expect = 9e-07 Identities = 49/212 (23%), Positives = 97/212 (45%), Gaps = 8/212 (3%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIE 889 PP F + T + T+KL RVT P P ++WY++ + + P + ++ DG + Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDG-SCT 7011 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTVIL 948 L++ N+ IDSG Y C A+++AG +S ++ + V FV ++ + E E + Sbjct: 7012 LILDNLTG-IDSGQYMCFAASAAGNASTLGKILVQVPP-RFVNKVRATPFVEGEDAQITC 7069 Query: 949 ECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX--XXXXXXXXXXXDVGVIKCIVKDQET 1006 + + +WY + ++ + ++ E R D+G +C + ++ Sbjct: 7070 TVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRLG 7129 Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 ST + + + +D +E+ VA +EV Sbjct: 7130 STRGGGELYMQSPALRARDQHHREQIVAAVEV 7161 Score = 59.7 bits (138), Expect = 9e-07 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G QF+ +EG+P P +TW++ + + S D +LV+ +V P DAG +TC Sbjct: 7319 GDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQR-QDGTTYSLVLTDVAPHDAGVYTC 7377 Query: 584 VAKNAAGFASSTTELIV 600 VA NA G EL+V Sbjct: 7378 VANNAGGQVLCKAELLV 7394 Score = 58.8 bits (136), Expect = 2e-06 Identities = 28/94 (29%), Positives = 50/94 (53%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F E+L G TV+ C+V G P+P ++W++ ++ + D D TL+ Sbjct: 6954 PEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTLI 7013 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + D+G + C A +AAG AS+ +++V+ P Sbjct: 7014 LDNLTGIDSGQYMCFAASAAGNASTLGKILVQVP 7047 Score = 54.8 bits (126), Expect = 2e-05 Identities = 48/200 (24%), Positives = 80/200 (40%), Gaps = 14/200 (7%) Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L P+ +V DA L+ +I + T V+W K + +E +F L D L I Sbjct: 12 LTRPKAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDL 71 Query: 1259 TEDDQCEYTC----VLLDAKSTTKLKVE----VVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 D +Y C + +A + L+V+ E P + R++ G+D T Sbjct: 72 ALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADATFRCR 131 Query: 1311 YQAFPQPNDEWIVNSKII--KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 PQP W + + + H + +S++L I+ D G Y++R EN G Sbjct: 132 VGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGS 191 Query: 1369 ADVEMNVTI---LDKPSPPG 1385 A + + + PPG Sbjct: 192 ASAAAALVVDSDAEVAGPPG 211 Score = 53.2 bits (122), Expect = 8e-05 Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Query: 816 TSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 T AV + P + ++ P+F+ Q V++ + VT PVPS+ W+++ +++ Sbjct: 6050 TPAVPLAKTPGLQTSDAAPVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLE 6109 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + N D + +I D G Y+C+A NS G SS A + +++ + Sbjct: 6110 EDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVELTSTDY 6165 Score = 52.4 bits (120), Expect = 1e-04 Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 7/139 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F ++ + G + L CR+ P+P ++W G+ + D + + IE D C Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPH-HILIE-DPDGSC 7010 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +++ + N+ G Y A + G AS + ++ PP+ + +++ +GE Sbjct: 7011 TLI-LDNLTGIDSGQYMCFAASAAGNASTLGKILVQV----PPRFVNKVRATPFVEGEDA 7065 Query: 753 ILSAQVVGNPRPTITWCKN 771 ++ V G P P I W K+ Sbjct: 7066 QITCTVEGAPYPQIRWYKD 7084 Score = 52.0 bits (119), Expect = 2e-04 Identities = 36/141 (25%), Positives = 67/141 (47%), Gaps = 8/141 (5%) Query: 809 NSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 +S+ I ET+ V + P P +++ V+ + A + +P P +TWY Sbjct: 7280 HSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWY 7339 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923 + + ++ S ++Q DG LV+T+V + D+G Y CVA+N+ G+ A + + Sbjct: 7340 KGSTQLTSSARLSQRQDGTTYSLVLTDV-APHDAGVYTCVANNAGGQVLCKAELLVHGGD 7398 Query: 924 --DVEKVTFVKHLQKSYETEE 942 D E + + L Y+ +E Sbjct: 7399 KLDAENQVYRRKLHSFYDVQE 7419 Score = 51.6 bits (118), Expect = 2e-04 Identities = 46/234 (19%), Positives = 90/234 (38%), Gaps = 11/234 (4%) Query: 1228 TWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 TW + +EK ++ + + L+++ D C T + D ++ L V Sbjct: 5314 TWLLDDEPVHTSEKVEVVYFENGLRHLLLLKNLKPQDSCRVTFLAGDVVTSAFLTVRGWR 5373 Query: 1286 FPPKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHT-KPSIDSKSA 1343 ++++ + +K G V + +A P W +N I+ + D Sbjct: 5374 L--EVLEPPHDASVKAGMQVRFTCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHH 5431 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 +LT+ + AG + A +++L P PP ++ S+ + W Sbjct: 5432 ALTLSNAQPQHAGEVTFAARDAVASA----RLSVLALPDPPEDAEVVGRSDHSVTLSWVA 5487 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAV 1456 P + G + Y VE +E T +W ++ + + +L +YRFR AV Sbjct: 5488 PMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPGPECVVDDLVPGKTYRFRVAAV 5541 Score = 49.6 bits (113), Expect = 0.001 Identities = 28/90 (31%), Positives = 40/90 (44%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 + AP F+ +L + G +V CQV P Q TW + +++ S + N Sbjct: 8381 RDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNF 8440 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASST 595 L I V ED GT+TC N G A +T Sbjct: 8441 QLLTILVVKEEDLGTYTCCVSNPLGTAVTT 8470 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 G+ + P + ++ ED++ + VGD AVIEG PPP V WYK +L + + Sbjct: 7300 GVTRAPSMQVTIEDVQVQ--VGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDG 7357 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 T + + ++ + YT A+N G + L V+ Sbjct: 7358 TTYSLVLTDVAPHDAGVYTCVANNAGGQVLCKAELLVH 7395 Score = 46.8 bits (106), Expect = 0.007 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 4/145 (2%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVV 1284 V+WYK +E LI D TLI+ T D +Y C A + + L +V Sbjct: 6985 VSWYKDGKPVEVDPHHILIEDPDGSCTLILDNLTGIDSGQYMCFAASAAGNASTLGKILV 7044 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343 + PP+ V+ R G D + + P P W + ++ + + +S Sbjct: 7045 QVPPRFVNKVRATPFVEGEDAQITCTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGV 7104 Query: 1344 -SLTIKKVENTDAGIYKLRLENNCG 1367 L I+ D G Y+ L N G Sbjct: 7105 LVLVIQAASKEDLGHYECELVNRLG 7129 Score = 46.0 bits (104), Expect = 0.011 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 7/88 (7%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT--NYIIEFKTVKGKSWTKIVTVGG 1920 L PP+ P VV T SVTL W+ P +G P+T Y++E + + +W++ G Sbjct: 511 LYPPADP---VVKAKTESSVTLSWSAP-PHGDRPVTIDGYVLEKRKLGAYAWSRCHEAGW 566 Query: 1921 -SVHEHCIENIKEKDEIIFRISAENTVG 1947 + E I + E+ + FR+SA N G Sbjct: 567 LATTEFTITGVAEEGDFQFRVSAINHFG 594 Score = 46.0 bits (104), Expect = 0.011 Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 3/123 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-- 1653 ++G P P++ W+K+G L +T K+ + I + R S +Y SN G Sbjct: 6224 VKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLEIVSVTREDSGQYAAYISNAVGAAY 6283 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNR 1712 SS + ++ +P + + + + ++ P G +T +E H + Sbjct: 6284 SSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTPKKVKRGSSITFSVKVEGHPAPSVH 6343 Query: 1713 WIK 1715 W+K Sbjct: 6344 WLK 6346 Score = 46.0 bits (104), Expect = 0.011 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD 785 TG P + ++ + V+ G+ A + G+P P +TW K + + + L + DG Sbjct: 7299 TGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTWYKGSTQLTSSARLSQRQDGT 7358 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 T+S+ +L D GVYT A N+ G A + V + +AE ++ Sbjct: 7359 TYSL-VLTDVAPHDAGVYTCVANNAGGQVLCKAELLVHGGDKLDAENQVY 7407 Score = 45.2 bits (102), Expect = 0.020 Identities = 47/191 (24%), Positives = 87/191 (45%), Gaps = 28/191 (14%) Query: 1107 PEIITRLQNQKVNKGNK-ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P+++ L++ +V G + A F++++ A + WFKDG + S+HI++T L+ Sbjct: 6200 PQVLEELKDLQVAPGTRLAKFQLKVKGYPAPKLYWFKDGQPLTTSDHIRMTDKKTLHTLE 6259 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTV-----------EEPSINFTLRL-PEFIL----- 1207 I +D+G+Y+ + N+ A + E+P+ + RL P IL Sbjct: 6260 IVSVTREDSGQYAAYISNAVGAAYSSARLLVRGPSEPEEKPASDVHERLVPPRILEKFTP 6319 Query: 1208 --VPANTDAYLTVEIPDETL-DVTWYK---KKSVI---EDTEKFTLISDVKKRTLIIRKC 1258 V + +V++ V W K +K V+ DT +T+ S K+ +L++ Sbjct: 6320 KKVKRGSSITFSVKVEGHPAPSVHWLKEEAEKGVLWIGPDTPGYTMASSSKQHSLVLLDV 6379 Query: 1259 TEDDQCEYTCV 1269 Q YTC+ Sbjct: 6380 GRQHQGTYTCI 6390 Score = 44.0 bits (99), Expect = 0.046 Identities = 43/197 (21%), Positives = 75/197 (38%), Gaps = 16/197 (8%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544 K +D L+C G P P V+W +D + ++ A + Sbjct: 16 KAFVVSVGKDATLSCQIVGNPTPHVSWEKDRQPVEAGARFRLAQDGDVYRLTILDLALGD 75 Query: 1545 XXXYKCIAFNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y C A N GE + + + +Q P + I+ + G + + Sbjct: 76 SGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVRE--GADATFRCRVG 133 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 G P P V W K+G +L ++ +E ++S +RI+ + Y + A N G++S Sbjct: 134 GSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSALRIRSARPRDGGTYEVRAENPLGSAS 193 Query: 1656 VEVTLKVYDKPSKPEGP 1672 L V D ++ GP Sbjct: 194 AAAAL-VVDSDAEVAGP 209 Score = 43.6 bits (98), Expect = 0.061 Identities = 43/204 (21%), Positives = 84/204 (41%), Gaps = 15/204 (7%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PPE L + G +T +V W+KDG ++ H L D Sbjct: 6953 PPEFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPHHILIEDPDGSCTL 7012 Query: 1165 IYD-CDLDDAGEYSC----EVGNSKCTAILTVEEPS--INFTLRLPEFILVPANTDAYLT 1217 I D D+G+Y C GN+ + V+ P +N +R F+ DA +T Sbjct: 7013 ILDNLTGIDSGQYMCFAASAAGNASTLGKILVQVPPRFVN-KVRATPFV---EGEDAQIT 7068 Query: 1218 VEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAK 1274 + + WYK +++ ++ ++++ + L+I+ +++D Y C L++ Sbjct: 7069 CTVEGAPYPQIRWYKDGTLLAPGNRYRMLNEPRSGVLVLVIQAASKEDLGHYECELVNRL 7128 Query: 1275 STTKLKVEVVEFPPKIVDYEREYR 1298 +T+ E+ P + ++ +R Sbjct: 7129 GSTRGGGELYMQSPALRARDQHHR 7152 Score = 43.2 bits (97), Expect = 0.081 Identities = 40/144 (27%), Positives = 57/144 (39%), Gaps = 2/144 (1%) Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKK-QKLK 1164 P + L ++ V G T + L + A W KDG ++ S H+ ++ K Q L Sbjct: 8385 PSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLT 8444 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I +D G Y+C V N TA+ T P + DA L V P E+ Sbjct: 8445 ILVVKEEDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVES 8504 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDV 1248 Y + IE TL SD+ Sbjct: 8505 CGPVTYIVQCCIEGGSWTTLASDI 8528 Score = 42.7 bits (96), Expect = 0.11 Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 9/151 (5%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P + W K+G LE+ I++ K ++ I +K YT SN GT+ Sbjct: 8412 PTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTCCVSNPLGTAVTTG 8471 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE-LTKYAIEKHEPDNNRWIKVA 1717 L+ ++PS P + E+ +++V + WKP G + + + IE W +A Sbjct: 8472 VLRKAERPSSSPRPEV-GELYKDAVLLVWKPVESCGPVTYIVQCCIE-----GGSWTTLA 8525 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 D Y KL+ Y+FR + G Sbjct: 8526 SDISDC-CYLTGKLSRGGMYIFRTACVSKAG 8555 Score = 42.3 bits (95), Expect = 0.14 Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 L P P + V + SVTL W P S+GG + Y +E K W + Sbjct: 5462 LALPDPPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDLVPG- 5520 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 E ++++ FR++A G P V L + A P+P AP Sbjct: 5521 PECVVDDLVPGKTYRFRVAAVGPAGAGEP-----VHLPQMAPAPAPAPAP 5565 Score = 42.3 bits (95), Expect = 0.14 Identities = 40/170 (23%), Positives = 68/170 (40%), Gaps = 6/170 (3%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKL 1360 G VTL A P W + +++ H S K+ L TI V+ D G Y Sbjct: 8399 GQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQLLTILVVKEEDLGTYTC 8458 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + N G A + ++PS +P + E+ ++ + W E+ G T Y+V+ Sbjct: 8459 CVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPVESCGPVT---YIVQCC 8515 Query: 1421 EIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I+ W ++ +I+ L Y FR V++ + S +E Sbjct: 8516 -IEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSE 8564 Score = 41.5 bits (93), Expect = 0.25 Identities = 23/102 (22%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F+E LR + P+ STV C++ + + W + + ++ + + D V L IR Sbjct: 4748 FIEDLRSQEAPESSTVTLRCKLS--KKASVVWKKGSETLRNGARYSL-RQDGAVCELEIR 4804 Query: 572 EVFPEDAGTFTCVA---KNAAGFASSTTELIVEAPLSDHGSE 610 ++ ED G ++C + +A + +++ + PL + +E Sbjct: 4805 DLTVEDTGEYSCTCGQERTSATLSIMAPQVVFQQPLQNLQAE 4846 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%) Query: 509 API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 AP+ F+ +L+ + +G+T + C++ + W + + + P +QM + A Sbjct: 4921 APVRFLRELQAQDVDEGATARLRCELSR-EAVSVEWRKGSLQLFPCAKYQMV-QEGTTAE 4978 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L++ V EDAG +TC AG S L V AP Sbjct: 4979 LLVHGVEQEDAGEYTC----DAGHTQSIARLSVRAP 5010 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGK-KQKLK 1164 P +T LQNQ V G +F+ +T VRWFKDG ++ +H + D + +L Sbjct: 6068 PVFLTELQNQDVQDGYPMSFDCVVTGQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 6127 Query: 1165 IYDCDLDDAGEYSCEVGNS 1183 I D G Y C NS Sbjct: 6128 ITAVVPADMGVYRCLAENS 6146 Score = 41.1 bits (92), Expect = 0.33 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGD 785 G + P + L V G+SV L+ QV+ P TW K+ +++ L + + + Sbjct: 8380 GRDQAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKN 8439 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 +TIL K+ +D G YT N G A T+ V+ E + P Sbjct: 8440 FQLLTILVVKE-EDLGTYTCCVSNPLGTAVTTGVLRKAERPSSSPRP 8485 Score = 40.7 bits (91), Expect = 0.43 Identities = 49/224 (21%), Positives = 85/224 (37%), Gaps = 9/224 (4%) Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSH-GARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 E IT V E D ++ A N G+ + T+ + + VK K+ E EG V Sbjct: 571 EFTITGVAEEGDF-QFRVSAINHFGQGPYLEFPGTMHLVPMLAVKTPLKAVEAVEGGEVT 629 Query: 948 LECQTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 + S +W+ + + + I R +K + ET Sbjct: 630 FSVDLTVASSGEWFLDGEALKASSIYVIRCDRTRHMLTIREVPARLHGAQLKFVANGIET 689 Query: 1007 STMLVVKETIPEFIRKLQDFEVKE-----KDVAILEVEINSETADVVWERDGEIIKPKKN 1061 S +VV+ + KL +E + A L E++ + A V W +DG + Sbjct: 690 SIQMVVRAALGLPSSKLPAAAAREVLAQLHEEAQLLAELSDQAAAVTWLKDGRELSLGP- 748 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 KY+ + R L +R+ + D G Y C+ R ++ V ++ Sbjct: 749 KYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQLLVQDI 792 Score = 40.7 bits (91), Expect = 0.43 Identities = 20/65 (30%), Positives = 31/65 (47%) Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188 EL+ A V W KDG E+ ++ + ++ L + D DDAG Y C S+ Sbjct: 727 ELSDQAAAVTWLKDGRELSLGPKYEMQVSAGRRALLVRDVAQDDAGLYECVSRGSRTAYQ 786 Query: 1189 LTVEE 1193 L V++ Sbjct: 787 LLVQD 791 Score = 40.7 bits (91), Expect = 0.43 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 13/142 (9%) Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971 WT VT GS H + N + + +A + V S RL A +P PP Sbjct: 5422 WT--VTTDGSHHALTLSNAQPQHAGEVTFAARDAVA--------SARLSVLA-LPDPPE- 5469 Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031 E+ + V SW P DGG L GY + +++ + W + V + + DL Sbjct: 5470 DAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLCHDL-VPGPECVVDDL 5528 Query: 2032 SENHTYMIRIYARNEIGLSEPL 2053 TY R+ A G EP+ Sbjct: 5529 VPGKTYRFRVAAVGPAGAGEPV 5550 Score = 40.7 bits (91), Expect = 0.43 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 1/104 (0%) Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139 VH + R C A T V P + +++ +V G+ A F+ + +V W Sbjct: 7279 VHSQVIMETTQRTYVCQAPDTGVTRAPSMQVTIEDVQVQVGDMAQFDAVIEGHPPPIVTW 7338 Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 +K +++ S + DG L + D DAG Y+C N+ Sbjct: 7339 YKGSTQLTSSARLSQRQDGTTYSLVLTDVAPHDAGVYTCVANNA 7382 Score = 40.3 bits (90), Expect = 0.57 Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 5/89 (5%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIK 1633 + N+D++ + + + +VT G P P V W+K+G LE D Y I ++ + I Sbjct: 6074 LQNQDVQDGYPMSFDCVVT----GQPVPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIIT 6129 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + + Y A N+ G SS + L+V Sbjct: 6130 AVVPADMGVYRCLAENSMGVSSTKAELRV 6158 Score = 39.9 bits (89), Expect = 0.75 Identities = 38/181 (20%), Positives = 70/181 (38%), Gaps = 12/181 (6%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXX---XXX 1543 + T + L+C G P+P+ W +DG+ + + YE+ Sbjct: 243 RTCTVTEGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQS 302 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPP 1602 Y C A N G+ +S +V +++ T+ + Q +V ++ T E P Sbjct: 303 DRGLYTCTASNLVGQTYSSVLVVVREP---TVPFKKRLQDLEVREKESATFQCEVAQPAT 359 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY---TIEASNTAGTSSVEVT 1659 E W+K +L +Y+I + + ++ + + Y T E S T SV+ Sbjct: 360 EAAWFKEETRLWASAKYDIEEEGTERRLTVRNVSADDDAVYICETTEGSRTVAELSVQGN 419 Query: 1660 L 1660 L Sbjct: 420 L 420 Score = 39.1 bits (87), Expect = 1.3 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKYTIEASNT 1650 ++ + G P PE +W K+G + + + + E+ + V++I K+S YT ASN Sbjct: 255 LSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQENFVLKILFCKQSDRGLYTCTASNL 314 Query: 1651 AGTSSVEVTLKVYDKPSKP 1669 G + V L V +P+ P Sbjct: 315 VGQTYSSV-LVVVREPTVP 332 Score = 39.1 bits (87), Expect = 1.3 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 3/76 (3%) Query: 509 API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 AP+ F +KL P+ + ++V E ++ P P++ W R A++ PS++ ++ + Sbjct: 2419 APVLFKKKLEPQTVEERTSVTLEVELTR-PWPEVKWTRNAAVLTPSENVEIRAEGAR-HC 2476 Query: 568 LVIREVFPEDAGTFTC 583 LV+R V D G F C Sbjct: 2477 LVLRSVGFADRGFFGC 2492 Score = 39.1 bits (87), Expect = 1.3 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T +++ P F+E LR + +G+ CQ+ + W + + ++ + + Sbjct: 4474 TLSVKALPPRFIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGSETLRDGDRYSL-RQ 4530 Query: 562 DDNVATLVIREVFPEDAGTFTCV 584 D V L IR++ EDAG + CV Sbjct: 4531 DGAVCELQIRDLAVEDAGEYLCV 4553 Score = 38.7 bits (86), Expect = 1.7 Identities = 28/130 (21%), Positives = 49/130 (37%), Gaps = 7/130 (5%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 FV +LR K +G T +C++ + W + T ++ + + D V L IR Sbjct: 3796 FVRRLRSKEATEGDTTTLQCELS--KAAPVEWRKGTETLRDGDRYSL-KQDGAVCELQIR 3852 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 + DAG + C G ++ L V A + + ++ + Sbjct: 3853 SLTIADAGEYLC----TCGQEKTSATLTVRALPAKFKDSLKNEEATEGTTATLSCELSKA 3908 Query: 632 IPPTFSKKPK 641 P T+ K PK Sbjct: 3909 APVTWKKGPK 3918 Score = 38.7 bits (86), Expect = 1.7 Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 LE+E+ ++ +VVW + E I+P ++ RG + L I+ D+GEY C Sbjct: 5582 LELEVAADGGEVVWHKGTERIQP-GGHFEVLSRGQRQMLVIKGFRTEDQGEYRC 5634 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 FV KLR K +G+TV C++ + W + T ++ + + D V L I Sbjct: 3708 FVGKLRNKEATEGTTVTLRCELT--KEAPVEWKKGTETLRNGDKYSL-KQDGAVCELQIC 3764 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + DAG ++CV A+ T + ++ Sbjct: 3765 SLLVADAGEYSCVCGQEKTSATLTVKALL 3793 Score = 37.1 bits (82), Expect = 5.3 Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 8/98 (8%) Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 +P ++W K G +L+ D + + + +++L+R + +Y+ + ++++ V Sbjct: 4859 VPNAAMVWSKGGLELQGDTRREARQQGCVAELLLRDLRREDAGEYSCTCGSQTTSATLMV 4918 Query: 1659 T------LKVYDKPSKPEGPV--IMREISRESVTIEWK 1688 T L+ EG + E+SRE+V++EW+ Sbjct: 4919 TAAPVRFLRELQAQDVDEGATARLRCELSREAVSVEWR 4956 Score = 37.1 bits (82), Expect = 5.3 Identities = 20/83 (24%), Positives = 35/83 (42%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 + P F+ + V ++ L +V P TW ++ ++ S + + +N +L Sbjct: 8383 QAPSFLRELSDEAVVLGQSVTLACQVLAQPTAQATWSKDGVLLESSGHLLISSTLKNFQL 8442 Query: 891 VITNVDSEIDSGDYKCVASNSAG 913 + V E D G Y C SN G Sbjct: 8443 LTILVVKEEDLGTYTCCVSNPLG 8465 Score = 36.7 bits (81), Expect = 7.0 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T +++ P F+E LR + +G+ CQ+ + W + + ++ + + Sbjct: 4298 TLNVKALPPRFIEDLRSQEATEGTMATLRCQMS--KAAPVEWRKGSETLRDGGRYSL-RQ 4354 Query: 562 DDNVATLVIREVFPEDAGTFTCV 584 D V L I ++ EDAG ++CV Sbjct: 4355 DGAVCELQIHDLDVEDAGQYSCV 4377 Score = 36.3 bits (80), Expect = 9.2 Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 16/168 (9%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITIL 792 V+ L+++ +G + Q+ TW +++PV K + + +L Sbjct: 5284 VLRGLENVDALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSEKVEVVYFENGLRHLLLL 5343 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K K +D T A G TSA +TV E EPP + +VK ++ Sbjct: 5344 KNLKPQDSCRVTFLA----GDVVTSAFLTVRGWRLEVLEPP------HDASVKAGMQVRF 5393 Query: 853 VARVTRN-PVPSITWYRNNEIISPSET-ITQNFDGENIELVITNVDSE 898 ++ PV TWY N I P +T T DG + L ++N + Sbjct: 5394 TCILSEAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQ 5441 >UniRef50_UPI0000F1EF40 Cluster: PREDICTED: similar to novel immunoglobulin I-set domain containing protein; n=2; Danio rerio|Rep: PREDICTED: similar to novel immunoglobulin I-set domain containing protein - Danio rerio Length = 1523 Score = 198 bits (482), Expect = 2e-48 Identities = 244/1095 (22%), Positives = 443/1095 (40%), Gaps = 93/1095 (8%) Query: 628 ILEGIPPTFSKKPKAQY---VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 IL+ P TF+ P+ + E +ILL C+ V+ + W G E+ N+ + + Sbjct: 327 ILQSPPVTFAYIPEDDLHRNIVEQDNILLHCQ-VSRSDATAQWYKDGVELKSTSNVLIEV 385 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKS 743 E+D+ L I + GTYT R G+++L V K+ +EPP ++ P + Sbjct: 386 ENDIRR----LIILSAHLSDSGTYTC----RAGDSAL--VFKVNV--REPPVMIVYPKED 433 Query: 744 MIVRQG--ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK 798 + + + E ++LS ++ P +TW K+ + ++ + K++G + IL ++ Sbjct: 434 VHLDRHVPEEIVLSCEL-SRPNGKVTWFKDGQKLQESENIKLKTEGPYRRLKILH-SGIE 491 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G Y + + ++EP P E+ + + L ++R Sbjct: 492 DSGEYVCDTADDSIFFN----LNIKEPPVRIVSPS---QSQMELCQQTSERMVLSCEISR 544 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P ++ WYR+ + S+++ DG L+I + DS +Y C ++ S Sbjct: 545 -PNATVRWYRDGLEVEESDSLILEVDGVYRRLIIPKPTVK-DSAEYVCDTTDD----SVT 598 Query: 919 ARVTIDVEKVTFVKHLQKSYETEE--GKTVILECQTSH-TVSTKWYHNKKEISGMDHREI 975 V I V F++ + +Y E+ G+ V+LEC+ W + EI + I Sbjct: 599 FFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVLECEVCRPNAEVSWKKDGDEIEENSNVTI 658 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---- 1031 ++G D G C +D ++ +K+ + +RK D E K + Sbjct: 659 TEDGTNRQLTIHSADFEDAGQYVCDARDDVMDFLVKIKDPPLKILRKA-DIETKRQFMVS 717 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 D +L+ EI+ V W +D E I ++ + E+ G R L + N + D GEY C Sbjct: 718 DAIVLKCEISRANGVVNWLKDNEKIDGNEH-FTCEEEGAFRSLIVLNAELRDSGEYICDA 776 Query: 1092 RDESCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 +D+ VTV E P I+ Q K + G++ + E E+++ +A+V+W+ +G ++ Sbjct: 777 QDDKVVFSVTVEEAPVSIVGNTQKPKHCILLTGDELSLECEVSRVNAVVQWYCNGRLLKQ 836 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 + + +KL I D+GEY C+ + K +LTV++ F ++ E + Sbjct: 837 DSRTHIESSDTMRKLVISGLQTSDSGEYLCDATDDKMITMLTVQDLPFKF-IKKDEKTNI 895 Query: 1209 PANTDAYLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 A + LT+ ++ + W + + +I ++F SD L I D EY Sbjct: 896 SAYEEDSLTLRATVNRVNAPIKWQRGRDLIRG-DRFNTTSDGNTHYLTINPLKRGDSGEY 954 Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 TC L V V K +GS+V L + + + +W+ +S+ Sbjct: 955 TCHL--GTDEMHFSVHVKAMKVKFSKPLENIAGLKGSNVVLKCELYK-SKGDVQWLKDSQ 1011 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV-TILDKPSPPG 1385 I +H + + SLTI + DAG Y ++ A V +N+ I++ + Sbjct: 1012 EIAASRHFTIRAEGRVRSLTIHNITEDDAGEYACESKDERTSATVMVNIPRIVEFVAELH 1071 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLK 1444 ++E + ++ C PE+ S + Q I + E ++ N I+N + Sbjct: 1072 NMTVMEGEDATFK-CVVSPEDAKLS----WFKNGQHISSNEKFNISSNGLCHMLHIKNCQ 1126 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + S A A E IS A + +V+ TK P V + T E E Sbjct: 1127 VSDSCSLTAEA--EGVISRALLQVQEAQVL-FTKSMDPVVAEEFGEATLEVEVSTETA-- 1181 Query: 1505 FGGVPQPKVTWYRDGKKLKT-AKATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 +V W R G + +K T + Y C +D + + Sbjct: 1182 -------EVQWMRQGVVIHPGSKFTLRQSGRKRSLTIHKLTLLDRGTYSCETLHDRTQAK 1234 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 S +K I DI+ + + V + E +W K+G+ L+ + Sbjct: 1235 LSVE---PRKIKIRKGLTDIQTIERETASFEVELSHSNV---EGVWQKDGHVLKTNNRLR 1288 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV------TLKVYDKPSKPEGP-- 1672 +T + + + I L + Y N + ++V LK D +PEG Sbjct: 1289 MTAQGRVHSLTISGLTLDDTGTYIFSVDNVRSLARLDVKEIPVSILKKLDDIRQPEGSGV 1348 Query: 1673 VIMREISRESVTIEW 1687 + E+SR ++ I+W Sbjct: 1349 TLECELSRHNIDIKW 1363 Score = 169 bits (412), Expect = 5e-40 Identities = 174/733 (23%), Positives = 304/733 (41%), Gaps = 40/733 (5%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 ++KPK + G ++ LEC + + + W G + D + M L Sbjct: 798 TQKPKHCILLTGDELSLECEVSRV-NAVVQWYCNGRLLKQDSRTHIESSDTMRK----LV 852 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I+ ++ G Y A + + L + L K +K+ I + +S+ L Sbjct: 853 ISGLQTSDSGEYLCDATDDKMITMLTVQDLPFKFIKKDEKTNISAYEE------DSLTLR 906 Query: 756 AQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 A V I W + ++ T SDG+TH +TI P K D G YT G Sbjct: 907 A-TVNRVNAPIKWQRGRDLIRGDRFNTTSDGNTHYLTI-NPLKRGDSGEYTCHL----GT 960 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 E + V+ + ++P + I + + L + ++ + W ++++ I Sbjct: 961 DEMHFSVHVKAMKVKFSKP------LENIAGLKGSNVVLKCELYKSK-GDVQWLKDSQEI 1013 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVK 932 + S T +G L I N+ +E D+G+Y C + + ++S A V +++ ++ FV Sbjct: 1014 AASRHFTIRAEGRVRSLTIHNI-TEDDAGEYACESKDE--RTS--ATVMVNIPRIVEFVA 1068 Query: 933 HLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 L + EG+ +C S W+ N + IS + I G Sbjct: 1069 ELH-NMTVMEGEDATFKCVVSPEDAKLSWFKNGQHISSNEKFNISSNGLCHMLHIKNCQV 1127 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D + + + +L V+E F + + +E A LEVE+++ETA+V W R Sbjct: 1128 SDSCSLTAEAEGVISRALLQVQEAQVLFTKSMDPVVAEEFGEATLEVEVSTETAEVQWMR 1187 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 G +I P +K+ + G R L I ++ D G YSC + A+++V +I Sbjct: 1188 QGVVIHPG-SKFTLRQSGRKRSLTIHKLTLLDRGTYSCETLHDRTQAKLSVEPRKIKIRK 1246 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 L + + + A+FE+EL+ + W KDG ++ +N +++T G+ L I LD Sbjct: 1247 GLTDIQTIERETASFEVELSHSNVEGVWQKDGHVLKTNNRLRMTAQGRVHSLTISGLTLD 1306 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 D G Y V N + A L V+E ++ +L + I P + L E+ +D+ W K Sbjct: 1307 DTGTYIFSVDNVRSLARLDVKEIPVSILKKLDD-IRQPEGSGVTLECELSRHNIDIKWTK 1365 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 ++ + + S +K L I KC D Y C DA TT V++ E +I+ Sbjct: 1366 NGVQLKPGKNHRIYSMGRKCFLQILKCELGDSGLYVCDAGDA--TTSCSVDIYERELEIL 1423 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + I+ + + + P EW N + IK K ++ L I V+ Sbjct: 1424 QSLEDLDIQEDQNAVFMCEVSLDDVPG-EWFKNGEKIKPTSTIKIRQEANKHFLLICNVK 1482 Query: 1352 NTDAGIYKLRLEN 1364 D+G K +N Sbjct: 1483 EEDSGEIKFVAKN 1495 Score = 152 bits (369), Expect = 9e-35 Identities = 142/660 (21%), Positives = 280/660 (42%), Gaps = 39/660 (5%) Query: 629 LEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 ++ +P F KK + + E + L + + P I W +G +++ + + + Sbjct: 879 VQDLPFKFIKKDEKTNISAYEEDSLTLRATVNRVNAP-IKWQ-RGRDLIRGDRFNTTSDG 936 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMI 745 + H L I +K+ G YT E S+ + +K+K + PL+++ Sbjct: 937 NTHY----LTINPLKRGDSGEYTCHLGTDEMHFSVHVKAMKVKFSK--------PLENIA 984 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802 +G +V+L ++ + + + W K+++ + A +++G S+TI + D G Sbjct: 985 GLKGSNVVLKCELYKS-KGDVQWLKDSQEIAASRHFTIRAEGRVRSLTIHNITE-DDAGE 1042 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y ++++ TSA + V P F+ +TV E G V Sbjct: 1043 YACESKDER----TSATVMVNIPRIVE-----FVAELHNMTVME-GEDATFKCVVSPEDA 1092 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 ++W++N + IS +E + +G L I N D + + + G S A + Sbjct: 1093 KLSWFKNGQHISSNEKFNISSNGLCHMLHIKNCQVS----DSCSLTAEAEGVISR-ALLQ 1147 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 + +V F K + E G+ + ++ T +W I + Q GR Sbjct: 1148 VQEAQVLFTKSMDPVVAEEFGEATLEVEVSTETAEVQWMRQGVVIHPGSKFTLRQSGRKR 1207 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G C T L V+ + + L D + E++ A EVE++ Sbjct: 1208 SLTIHKLTLLDRGTYSCETLHDRTQAKLSVEPRKIKIRKGLTDIQTIERETASFEVELSH 1267 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 + VW++DG ++K N+ +G + L I ++ D G Y + + A + V Sbjct: 1268 SNVEGVWQKDGHVLKTN-NRLRMTAQGRVHSLTISGLTLDDTGTYIFSVDNVRSLARLDV 1326 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E+P I+ +L + + +G+ T E EL++ + ++W K+G +++ + ++ G+K Sbjct: 1327 KEIPVSILKKLDDIRQPEGSGVTLECELSRHNIDIKWTKNGVQLKPGKNHRIYSMGRKCF 1386 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 L+I C+L D+G Y C+ G++ + + + E + L E + + + +A E+ Sbjct: 1387 LQILKCELGDSGLYVCDAGDATTSCSVDIYERELEILQSL-EDLDIQEDQNAVFMCEVSL 1445 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + + W+K I+ T + + K L+I E+D E V + +ST L+VE Sbjct: 1446 DDVPGEWFKNGEKIKPTSTIKIRQEANKHFLLICNVKEEDSGEIKFVAKNVESTAYLEVE 1505 Score = 134 bits (325), Expect = 2e-29 Identities = 147/742 (19%), Positives = 298/742 (40%), Gaps = 52/742 (7%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T + + + ++ G L+C V+ P+ + W G E++P + I + E + Sbjct: 65 TIDEVQRNKCIESGRPFKLQCE-VSDPDAQVWWYKDGNEVLPQDGIVIGSEEGIR----T 119 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L + + GTY + + ++ ++IK + + E K+ ++L Sbjct: 120 LSVQAAELCHSGTYRC----QMNDDAITFHVEIKAPSLKFIPISEVEKNKSTEVDSPIVL 175 Query: 755 SAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + + + + WCK+ + P L + D +T I + + K+ D G YT + Sbjct: 176 KCE-LSDATSEVLWCKDGRELAPNPELNFQKDENTRKIKV-ESAKLSDTGNYTCHVQGD- 232 Query: 812 GIAETSAVITVEEPTEENA--EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 S + ++PT + + + + + + + ++ +GT++ + + + + + Sbjct: 233 ---TVSFKVDDQDPTAQVSWLKDGVELQQQSGLDIQSEGTMRKM--IIHSAELKHSGVYS 287 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 E + + I D ++ + V EI+ KC+ + G + + VT Sbjct: 288 CEAV--DDLIAFKVDVAAPPVMFSAV-PEIEKN--KCIEA--------GGPIILQSPPVT 334 Query: 930 FVKHLQKSYETE--EGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXX 986 F + E ++L CQ S + +T +WY + E+ + I E Sbjct: 335 FAYIPEDDLHRNIVEQDNILLHCQVSRSDATAQWYKDGVELKSTSNVLIEVENDIRRLII 394 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE--KDVAILEVEINSET 1044 D G C D + V+E + +D + + +L E++ Sbjct: 395 LSAHLSDSGTYTCRAGDSALVFKVNVREPPVMIVYPKEDVHLDRHVPEEIVLSCELSRPN 454 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W +DG+ ++ +N + G R+L I ++ + D GEY C D+S + + E Sbjct: 455 GKVTWFKDGQKLQESEN-IKLKTEGPYRRLKILHSGIEDSGEYVCDTADDSIFFNLNIKE 513 Query: 1105 LPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P I++ Q+Q + E+++ +A VRW++DG E++ S+ + L +DG + Sbjct: 514 PPVRIVSPSQSQMELCQQTSERMVLSCEISRPNATVRWYRDGLEVEESDSLILEVDGVYR 573 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVE 1219 +L I + D+ EY C+ + T + + EP + F ++ + L E Sbjct: 574 RLIIPKPTVKDSAEYVCDTTDDSVTFFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVLECE 633 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + +V+W K IE+ T+ D R L I +D +Y C DA+ Sbjct: 634 VCRPNAEVSWKKDGDEIEENSNVTITEDGTNRQLTIHSADFEDAGQYVC---DARDDVMD 690 Query: 1280 KVEVVEFPPKIVDYEREYRIKRG---SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 + ++ PP + + + KR SD +L + W+ +++ I +H Sbjct: 691 FLVKIKDPPLKILRKADIETKRQFMVSDAIVLKCEISRANGVVNWLKDNEKIDGNEHFTC 750 Query: 1337 SIDSKSASLTIKKVENTDAGIY 1358 + SL + E D+G Y Sbjct: 751 EEEGAFRSLIVLNAELRDSGEY 772 Score = 67.7 bits (158), Expect = 3e-09 Identities = 161/864 (18%), Positives = 325/864 (37%), Gaps = 80/864 (9%) Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + WY+ E + +TITQ+ + LV T+ S + AS + A V + Sbjct: 4 VCWYKEVEELPQCDTITQSEETIGA-LVKTDEPSHSEES-----ASETDDVPVQFA-VDL 56 Query: 924 DVEKVTF--VKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980 V F + +Q++ E G+ L+C+ S WY + E+ D I E Sbjct: 57 PAPPVMFSTIDEVQRNKCIESGRPFKLQCEVSDPDAQVWWYKDGNEVLPQDGIVIGSEEG 116 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV---AILE 1037 G +C + D + + +K +FI + + K +V +L+ Sbjct: 117 IRTLSVQAAELCHSGTYRCQMNDDAITFHVEIKAPSLKFIPISEVEKNKSTEVDSPIVLK 176 Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 E++ T++V+W +DG + P + +F+K + RK+ + + + D G Y+C ++ ++ + Sbjct: 177 CELSDATSEVLWCKDGRELAPNP-ELNFQKDENTRKIKVESAKLSDTGNYTCHVQGDTVS 235 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157 +V + ++ ++ + + + E T ++ +E++ S Sbjct: 236 FKVDDQDPTAQVSWLKDGVELQQQSGLDIQSEGTMRKMIIH----SAELKHSGVYSCEAV 291 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI---LTVEEPSINFTLRLPEFIL---VPAN 1211 K+ E+ +KC + ++ P + F +PE L + Sbjct: 292 DDLIAFKVDVAAPPVMFSAVPEIEKNKCIEAGGPIILQSPPVTFAY-IPEDDLHRNIVEQ 350 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 + L ++ WYK ++ T + + R LII D YTC Sbjct: 351 DNILLHCQVSRSDATAQWYKDGVELKSTSNVLIEVENDIRRLIILSAHLSDSGTYTCRAG 410 Query: 1272 DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIK 1329 D S KV V E P IV + + + R +++ + +PN + W + + ++ Sbjct: 411 D--SALVFKVNVREPPVMIVYPKEDVHLDRHVPEEIVLSCE-LSRPNGKVTWFKDGQKLQ 467 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + ++ K + L I D+G Y C AD + L+ PP + I Sbjct: 468 ESENIKLKTEGPYRRLKILHSGIEDSGEYV------CDTADDSIFFN-LNIKEPPVR--I 518 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 + S + +C + T ++ + T W + ++ L+ + Y Sbjct: 519 VSPSQSQMELC----QQTSERMVLSCEISRPNA-TVRWYR-DGLEVEESDSLILEVDGVY 572 Query: 1450 RFRAYAVNEVDISDASE----TTE----YYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 R + + + D++E TT+ ++ I E ++ K + E + L Sbjct: 573 --RRLIIPKPTVKDSAEYVCDTTDDSVTFFVNIAEPPVRFIRPRKMAYGVEKLVGEIVVL 630 Query: 1502 TCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 C P +V+W +DG +++ T NR Y C A +D Sbjct: 631 ECEVCR-PNAEVSWKKDGDEIEENSNVTITEDGTNR-QLTIHSADFEDAGQYVCDARDD- 687 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHK--VGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 +V I+ P+ + DI+ K + V D ++ I V W K+ K++ Sbjct: 688 ---VMDFLVKIKDPPLKILRKADIETKRQFMVSDAIVLKCEISR-ANGVVNWLKDNEKID 743 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSKPEG 1671 ++ + + + + + S +Y +A + SV E + + KP+ Sbjct: 744 GNEHFTCEEEGAFRSLIVLNAELRDSGEYICDAQDDKVVFSVTVEEAPVSIVGNTQKPKH 803 Query: 1672 PVIMR--------EISRESVTIEW 1687 +++ E+SR + ++W Sbjct: 804 CILLTGDELSLECEVSRVNAVVQW 827 Score = 39.1 bits (87), Expect = 1.3 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 4/105 (3%) Query: 1555 DHGEVETSCVVGIQQKPV-ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 D G+ TSC V I ++ + I S ED+ + ++ ++ +P W+KNG K+ Sbjct: 1403 DAGDATTSCSVDIYERELEILQSLEDLDIQEDQNAVFMCEVSLDDVPGE---WFKNGEKI 1459 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + I + + I +K S + A N T+ +EV Sbjct: 1460 KPTSTIKIRQEANKHFLLICNVKEEDSGEIKFVAKNVESTAYLEV 1504 >UniRef50_Q7YRF6 Cluster: Cardiac titin; n=4; Eutheria|Rep: Cardiac titin - Canis familiaris (Dog) Length = 2200 Score = 193 bits (471), Expect = 4e-47 Identities = 192/739 (25%), Positives = 322/739 (43%), Gaps = 44/739 (5%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE--NISVAIE 685 ++E I K + Q+V + C ++A P+I W FKG + +P E + + + Sbjct: 1444 VVEVIRDWLVKPIRDQHVKPKGTAVFTC-VIAKDTPNIKW-FKGYDEIPLEPNDKTEIVR 1501 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 H++ LK+ N + AV EG+ K+ GE+E ++++P++ + Sbjct: 1502 EGNHLF---LKVKNATPEDIDEH---AVEIEGKR---YPAKLTLGEREV-ELLKPIEDVT 1551 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGV 802 + + ES A++ P W + ++ PT K++G +T+ K K + G Sbjct: 1552 IYEKESASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLHKVK-LDQAGE 1609 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 +A N A T+A++TV+E + A P +++TV E+ + +TR Sbjct: 1610 VLYQALN----AFTTAILTVKEIELDFAVP------LKDVTVPERRQARFECVLTREA-- 1657 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 ++ W + +II S+ DG+ LVI DS D D + GK S AR+ Sbjct: 1658 NVIWSKGPDIIKASDKFDIIADGKKHILVIN--DSHFD--DEGVYTAEVEGKKS-SARLF 1712 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 + ++ F+ L+ +EG+T C+ SH + W+ N ++ I EG+ Sbjct: 1713 VTGIRLKFISPLEDQ-TVKEGQTATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKT 1771 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D+ I+ VKD +S L V E P F KL D EKD IL+ E+ Sbjct: 1772 HKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDEIILKCEV- 1830 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 S+ V W +DGE I P KY + G R L I+ + D+GEY C + A VT Sbjct: 1831 SKDVPVKWFKDGEEIVPSA-KYSIKTDGLRRILKIKKAELKDKGEYMCDCGTDQTKANVT 1889 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V ++ L ++ G A FEIEL++ D +W G + S ++ DGKK Sbjct: 1890 VEARLIKVEKPLYGVELFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKH 1949 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 L +Y+C LD GE S + N+K A L V+E + F L + + V +A E+ Sbjct: 1950 ILVLYNCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVS 2008 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 E W K I +K LI D K +L+I+ +D+ +Y D ++ KL + Sbjct: 2009 REPKTFRWLKGTQEITGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLII 2068 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 E + K + ++ K V+ + +W N + + + + K Sbjct: 2069 EGIRL--KFLTPLKDVTAKERESAVFTVEL-SHDNIRVKWFKNDQRLHTSRSVWMDDEGK 2125 Query: 1342 SASLTIKKVENTDAGIYKL 1360 + S+T + + D K+ Sbjct: 2126 THSITFRDLSIDDTSQIKV 2144 Score = 148 bits (359), Expect = 1e-33 Identities = 163/655 (24%), Positives = 298/655 (45%), Gaps = 46/655 (7%) Query: 629 LEGIPPTFSKKPKAQYVDE----GSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVA 683 L+ +P F K+ K + E GS + EC LV+ +W+ G I ++ +A Sbjct: 1254 LKAVPLKFVKEIKDIVLTEAEPVGSSAIFEC-LVSPSTAITSWMKDGSSIRESPKHRFIA 1312 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAV--NREGEASLPIVLKIKTGEKEPPQVIEPL 741 D ++ I +V+ G YT V N+E ++ +V+ E+ P + ++ L Sbjct: 1313 DGKDRKLH-----IMDVQLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTL 1362 Query: 742 KSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKK 796 + + V +G+ + LS ++ N + W K+ K V P K G ++TI Sbjct: 1363 EEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGKIVPGVIGLLRALTI-NDAD 1419 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 +D G YT+ EN+ + +S V VE + +P ++ VK KGT + Sbjct: 1420 DQDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP------IRDQHVKPKGTAVFTCVI 1473 Query: 857 TRNPVPSITWYRN-NEI-ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 ++ P+I W++ +EI + P++ +G ++ L + N E D ++ A GK Sbjct: 1474 AKD-TPNIKWFKGYDEIPLEPNDKTEIVREGNHLFLKVKNATPE-DIDEH---AVEIEGK 1528 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHR 973 + A++T+ +V +K ++ E ++ + + S + +W + + Sbjct: 1529 -RYPAKLTLGEREVELLKPIE-DVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTC 1586 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 EI EG G + + T+ +L VKE +F L+D V E+ Sbjct: 1587 EIKAEGGKRFLTLHKVKLDQAGEVLYQALNAFTTAILTVKEIELDFAVPLKDVTVPERRQ 1646 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 A E + E A+V+W + +IIK +K+D G L I ++ DEG Y+ + Sbjct: 1647 ARFECVLTRE-ANVIWSKGPDIIK-ASDKFDIIADGKKHILVINDSHFDDEGVYTAEVEG 1704 Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 + +A + V + + I+ L++Q V +G ATF EL+ V WFK+ +++ S + Sbjct: 1705 KKSSARLFVTGIRLKFISPLEDQTVKEGQTATFVCELSHEKMHVVWFKNDAKLHTSRTVL 1764 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 ++ +GK KL+I + LDD + +V + +A L V E FT++L + V + + Sbjct: 1765 ISSEGKTHKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKD-E 1823 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 L E+ + + V W+K I + K+++ +D +R L I+K D+ EY C Sbjct: 1824 IILKCEV-SKDVPVKWFKDGEEIVPSAKYSIKTDGLRRILKIKKAELKDKGEYMC 1877 Score = 145 bits (352), Expect = 1e-32 Identities = 123/553 (22%), Positives = 251/553 (45%), Gaps = 15/553 (2%) Query: 830 AEPPLFINRFQEITVKEKGTI--KLVARVTRNPVPSIT-WYRNNEIISPSETITQNFDGE 886 A P F+ ++I + E + + +P +IT W ++ I S DG+ Sbjct: 1256 AVPLKFVKEIKDIVLTEAEPVGSSAIFECLVSPSTAITSWMKDGSSIRESPKHRFIADGK 1315 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 + +L I +V D+G+Y CV + + A++ ++ V FVK L++ +G+ + Sbjct: 1316 DRKLHIMDVQLS-DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPL 1374 Query: 947 ILECQTSHTVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDVGVIKCIVKDQ- 1004 L C+ + W + K + + + G D G V++ Sbjct: 1375 YLSCELNKERDVVWRKDGKIVVEKPGKIVPGVIGLLRALTINDADDQDAGTYTVTVENAN 1434 Query: 1005 --ETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSETADVVWERD-GEIIKPKK 1060 E S+ + V E I ++ ++ ++D VK K A+ I +T ++ W + EI Sbjct: 1435 NLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAVFTCVIAKDTPNIKWFKGYDEIPLEPN 1494 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 +K + + G+ L ++N + D E++ + + A++T+ E E++ +++ + + Sbjct: 1495 DKTEIVREGNHLFLKVKNATPEDIDEHAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYE 1554 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 A+F+ E+++ D +W G ++ S ++ +G K+ L ++ LD AGE + Sbjct: 1555 KESASFDAEISEADIPGQWKLKGELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQA 1614 Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 N+ TAILTV+E ++F + L + + VP A + E +V W K +I+ ++ Sbjct: 1615 LNAFTTAILTVKEIELDFAVPLKD-VTVPERRQARFECVLTREA-NVIWSKGPDIIKASD 1672 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK 1300 KF +I+D KK L+I DD+ YT + KS+ +L V + K + + +K Sbjct: 1673 KFDIIADGKKHILVINDSHFDDEGVYTAEVEGKKSSARLFVTGIRL--KFISPLEDQTVK 1730 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 G T + + + + + W N + + S + K+ L I++V D + Sbjct: 1731 EGQTATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEIREVTLDDISQIRA 1789 Query: 1361 RLENNCGHADVEM 1373 ++++ A++++ Sbjct: 1790 QVKDLSSSANLKV 1802 Score = 138 bits (333), Expect = 2e-30 Identities = 152/643 (23%), Positives = 254/643 (39%), Gaps = 44/643 (6%) Query: 660 IPEPDIA--WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 I E DI W KGE + P + E L + VK Q G A+N Sbjct: 1564 ISEADIPGQWKLKGELLRPSPTCEIKAEGGKRF----LTLHKVKLDQAGEVLYQALN--- 1616 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 A +L +K E + PLK + V + + V + W K +KA Sbjct: 1617 -AFTTAILTVKEIELD---FAVPLKDVTVPERRQARF--ECVLTREANVIWSKGPDIIKA 1670 Query: 778 ---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 +DG H I ++ DEGVYT + E + +SA + V + Sbjct: 1671 SDKFDIIADGKKH-ILVINDSHFDDEGVYTAEVEGKK----SSARLFVTGIRLK------ 1719 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 FI+ ++ TVKE T V ++ + + W++N+ + S T+ + +G+ +L I Sbjct: 1720 FISPLEDQTVKEGQTATFVCELSHEKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLEIR- 1777 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK-HLQKSYETEEGKTVILECQTS 953 E+ D + + SS ++ + VK H + E +E +IL+C+ S Sbjct: 1778 ---EVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDE---IILKCEVS 1831 Query: 954 HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK 1013 V KW+ + +EI I +G D G C +T + V+ Sbjct: 1832 KDVPVKWFKDGEEIVPSAKYSIKTDGLRRILKIKKAELKDKGEYMCDCGTDQTKANVTVE 1891 Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK-RGHIR 1072 + + + L E+ + A E+E++ W+ GE + + E + HI Sbjct: 1892 ARLIKVEKPLYGVELFVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHIL 1951 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132 LY N + GE S + A + V ELP IT L + KV + ++A FE E+++ Sbjct: 1952 VLY--NCQLDMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSR 2009 Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 RW K EI + ++L DG K L I +D G+Y E + + L +E Sbjct: 2010 EPKTFRWLKGTQEITGDDKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLIIE 2069 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + F L + + A TVE+ + + V W+K + + + + K + Sbjct: 2070 GIRLKFLTPLKD-VTAKERESAVFTVELSHDNIRVKWFKNDQRLHTSRSVWMDDEGKTHS 2128 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDY 1293 + R + DD + + S KL + F K+ DY Sbjct: 2129 ITFRDLSIDDTSQIKVEAMGLSSEAKLTALEGDPYFTGKLQDY 2171 Score = 134 bits (325), Expect = 2e-29 Identities = 140/592 (23%), Positives = 249/592 (42%), Gaps = 41/592 (6%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVKKF 703 V E EC L E ++ W KG +I+ + + + H +L I + Sbjct: 1641 VPERRQARFECVLTR--EANVIWS-KGPDIIKASDKFDIIADGKKH----ILVINDSHFD 1693 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 EG YT ++ A L + TG + + I PL+ V++G++ ++ + + Sbjct: 1694 DEGVYTAEVEGKKSSARLFV-----TGIRL--KFISPLEDQTVKEGQTATFVCEL-SHEK 1745 Query: 764 PTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W KN+ + T S+G TH + I ++V + + ++A+ + +SA + Sbjct: 1746 MHVVWFKNDAKLHTSRTVLISSEGKTHKLEI---REVTLDDISQIRAQVKD--LSSSANL 1800 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 V E P F + + T EK I L V+++ VP + W+++ E I PS + Sbjct: 1801 KVLEAD------PYFTVKLHDKTGVEKDEIILKCEVSKD-VP-VKWFKDGEEIVPSAKYS 1852 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 DG L I + + D G+Y C G A VT++ + K L E Sbjct: 1853 IKTDGLRRILKIKKAELK-DKGEYMC----DCGTDQTKANVTVEARLIKVEKPLY-GVEL 1906 Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 G+T E + S V +W + ++ EII++G+ G + Sbjct: 1907 FVGETARFEIELSEPDVHGQWKLKGEPLTASPDCEIIEDGKKHILVLYNCQLDMTGEVSF 1966 Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 + +++ L VKE FI L D +V EKD A E E++ E W + + I Sbjct: 1967 QAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGD 2026 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 +K + K G L I++ + DEG+Y D+ + ++ + + + +T L++ Sbjct: 2027 -DKVELIKDGTKHSLVIKSAAFEDEGKYIFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAK 2085 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 + A F +EL+ + V+WFK+ + S + + +GK + D +DD + E Sbjct: 2086 ERESAVFTVELSHDNIRVKWFKNDQRLHTSRSVWMDDEGKTHSITFRDLSIDDTSQIKVE 2145 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 A LT E FT +L ++ V + + L EI V W++ Sbjct: 2146 AMGLSSEAKLTALEGDPYFTGKLQDYTGVEKD-EVILQCEISKADAPVKWFQ 2196 Score = 101 bits (241), Expect = 3e-19 Identities = 119/521 (22%), Positives = 220/521 (42%), Gaps = 41/521 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 GI F + Q V EG C L + + + W ++ + ++ E H Sbjct: 1715 GIRLKFISPLEDQTVKEGQTATFVCEL-SHEKMHVVWFKNDAKLHTSRTVLISSEGKTHK 1773 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + +E T ++ R L +K E +P ++ V + E Sbjct: 1774 L----------EIREVTLDDISQIRAQVKDLSSSANLKVLEADPYFTVKLHDKTGVEKDE 1823 Query: 751 SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +IL +V + + W K+ + P K+DG I +K ++KD+G Y Sbjct: 1824 -IILKCEV--SKDVPVKWFKDGEEIVPSAKYSIKTDG-LRRILKIKKAELKDKGEYMCDC 1879 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 G +T A +TVE + E PL+ E+ V E T + ++ V W Sbjct: 1880 ----GTDQTKANVTVEARLIK-VEKPLY---GVELFVGE--TARFEIELSEPDVHG-QWK 1928 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 E ++ S DG+ LV+ N ++ +G+ A+N+ KS+ A + + Sbjct: 1929 LKGEPLTASPDCEIIEDGKKHILVLYNCQLDM-TGEVSFQAANA--KSA--ANLKVKELP 1983 Query: 928 VTFVKHLQ--KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXX 984 + F+ L K +E +E K EC+ S T +W +EI+G D E+I++G Sbjct: 1984 LIFITPLSDVKVFEKDEAK---FECEVSREPKTFRWLKGTQEITGDDKVELIKDGTKHSL 2040 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G +D+ TS L+++ +F+ L+D KE++ A+ VE++ + Sbjct: 2041 VIKSAAFEDEGKYIFEAEDKHTSGKLIIEGIRLKFLTPLKDVTAKERESAVFTVELSHDN 2100 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W ++ + + ++ + + G + R+ S+ D + S A++T +E Sbjct: 2101 IRVKWFKNDQRLHTSRSVW-MDDEGKTHSITFRDLSIDDTSQIKVEAMGLSSEAKLTALE 2159 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145 P +LQ+ + ++ + E++K DA V+WF+DG+E Sbjct: 2160 GDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFQDGNE 2200 Score = 82.6 bits (195), Expect = 1e-13 Identities = 84/288 (29%), Positives = 123/288 (42%), Gaps = 13/288 (4%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 G+ A FE ++ A+ W KDGS I+ S + DGK +KL I D L DAGEY+C Sbjct: 1277 GSSAIFECLVSPSTAITSWMKDGSSIRESPKHRFIADGKDRKLHIMDVQLSDAGEYTCVL 1336 Query: 1179 EVGNSK--CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSV 1235 +GN + TA L VEE + F L E + V YL+ E+ E DV W K K V Sbjct: 1337 RLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKER-DVVWRKDGKIV 1395 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVE-FPPKIVDY 1293 +E K R L I + D YT + +A + V+VVE +V Sbjct: 1396 VEKPGKIVPGVIGLLRALTINDADDQDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKP 1455 Query: 1294 EREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKV 1350 R+ +K +G+ V V A PN +W I + K I + L +K Sbjct: 1456 IRDQHVKPKGTAVFTCV--IAKDTPNIKWFKGYDEIPLEPNDKTEIVREGNHLFLKVKNA 1513 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 D + + +E A + + ++ P I E +S+S + Sbjct: 1514 TPEDIDEHAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFD 1561 Score = 70.1 bits (164), Expect = 6e-10 Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 29/236 (12%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-----DGD 785 E P I+ + + + G+ LS V G P+P I W K V P+ DG+ Sbjct: 94 EGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFF--KGVMLTPSADYKFVFDGN 151 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-----------EPTEENAE--- 831 HS+ IL K +DEG YT A N G A SA + + EP E E Sbjct: 152 DHSLIILFTK-FEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFE 210 Query: 832 ---PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGE 886 PP F+ F+ I V P P++TW++ ++ + + TI N DG Sbjct: 211 GPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGS 270 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 +V N DSG Y C A N G+S+ A + + +E L+K+ T E Sbjct: 271 GTFIV--NDPQREDSGLYVCRAENMWGESTCTAELLVLLEDTDMTDALRKAKPTPE 324 Score = 69.3 bits (162), Expect = 1e-09 Identities = 59/216 (27%), Positives = 89/216 (41%), Gaps = 27/216 (12%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 EG P F K+ + G L + IP+P I W FKG + P + + + H Sbjct: 94 EGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDH 153 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT---GEKE------------- 733 L I K EG YT VA N G+A LKI + G+KE Sbjct: 154 S----LIILFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKF 209 Query: 734 ----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDT 786 PP ++ K + +G + V+G P PT+TW K +K + + + D Sbjct: 210 EGPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDG 269 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 I+ + +D G+Y +AEN G + +A + V Sbjct: 270 SGTFIVNDPQREDSGLYVCRAENMWGESTCTAELLV 305 Score = 68.5 bits (160), Expect = 2e-09 Identities = 48/219 (21%), Positives = 96/219 (43%), Gaps = 12/219 (5%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+++ P+F++++ G + V G P+P+I WF + ++ PS D++ +D Sbjct: 91 SKKEGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDG 150 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 ++ + +++ F ED G +TCVA N G A + L + + G + T Sbjct: 151 NDHSLIILFTKF-EDEGEYTCVASNEYGQAVCSASLKISS--KGEGQKET-----EAEPV 202 Query: 623 XXXADILEG-IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 + EG PP F K+ K + G + E ++ P P + W + +++ + + Sbjct: 203 ETFLEKFEGPCPPYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHT 262 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 + D + + ++ G Y A N GE++ Sbjct: 263 IIHNPD---GSGTFIVNDPQREDSGLYVCRAENMWGEST 298 Score = 62.9 bits (146), Expect = 9e-08 Identities = 61/206 (29%), Positives = 96/206 (46%), Gaps = 15/206 (7%) Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII-KPKKNKYDFEKRGH 1070 V E P + L D +E DV L I + +V W +G+++ +K K ++ + Sbjct: 879 VGEDGPVMLTPLVDTTAEEGDVVNLTSSITN-AKEVNWYFEGKLVHSDEKFKCLQDQNTY 937 Query: 1071 IRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVE-LPPEIITRLQNQKVNKGNKAT 1125 ++ NT H +G Y+C + S +A++TVV+ P I R++ +V G+ A Sbjct: 938 TLVIHGVNTEEH-QGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAK 996 Query: 1126 FEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EV 1180 F E+ + +WFK G EI S+ + L+I + D GEY+C E Sbjct: 997 FTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEY 1056 Query: 1181 GNSKCTAILTVEEPSINFTLR--LPE 1204 G+ CTA LTV P +R LPE Sbjct: 1057 GSVSCTATLTVTVPGAEKKVRKLLPE 1082 Score = 59.3 bits (137), Expect = 1e-06 Identities = 27/91 (29%), Positives = 49/91 (53%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ +P H G FE V G P P +TWF+++ + + + ++ D T + Sbjct: 215 PYFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESKQLCTNVYHTIIHNPDGSGTFI 274 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + ED+G + C A+N G ++ T EL+V Sbjct: 275 VNDPQREDSGLYVCRAENMWGESTCTAELLV 305 Score = 55.2 bits (127), Expect = 2e-05 Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 15/199 (7%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHS 788 ++ P ++ PL +G+ V L++ + + W K V + D +T++ Sbjct: 881 EDGPVMLTPLVDTTAEEGDVVNLTSSITNAKE--VNWYFEGKLVHSDEKFKCLQDQNTYT 938 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + I + +G YT +A N++G A TSA +TV + P+ R + + V Sbjct: 939 LVIHGVNTEEHQGAYTCEALNAKGNASTSAKLTVVK-----RAAPVIKRRIEPLEVALGH 993 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKC 906 K V P W++ I S+ +I + +E++ T V +D G+Y C Sbjct: 994 LAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQV---VDCGEYTC 1050 Query: 907 VASNSAGKSSHGARVTIDV 925 ASN G S A +T+ V Sbjct: 1051 KASNEYGSVSCTATLTVTV 1069 Score = 54.4 bits (125), Expect = 3e-05 Identities = 49/232 (21%), Positives = 86/232 (37%), Gaps = 7/232 (3%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P+ + + T +E + L + +T + WY +++ E D LVI Sbjct: 884 PVMLTPLVDTTAEEGDVVNLTSSITN--AKEVNWYFEGKLVHSDEKFKCLQDQNTYTLVI 941 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC-- 950 V++E G Y C A N+ G +S A++T+ +K + E G C Sbjct: 942 HGVNTEEHQGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEV 1001 Query: 951 QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETST 1008 Q + V +W+ +EI D I D G C ++ S Sbjct: 1002 QIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEYGSVSC 1061 Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 + T+P +K++ + K EV + S E + + ++PKK Sbjct: 1062 TATLTVTVPGAEKKVRKLLPEPKPQPKEEVVLKSVLRKRPEEEEPK-VEPKK 1112 Score = 52.8 bits (121), Expect = 1e-04 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 9/168 (5%) Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723 ++ W F+G+ + DE D + Y V+ N ++ Q G YT A+N +G AS Sbjct: 912 EVNWYFEGKLVHSDEKFKCL--QDQNTYTLVIHGVNTEEHQ-GAYTCEALNAKGNASTSA 968 Query: 724 VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPT 780 K+ ++ P + ++ + V G + +V P W K + + Sbjct: 969 --KLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSI 1026 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 +S ++ IL+ + V D G YT KA N G +A +TV P E Sbjct: 1027 RSSKYVSTLEILRTQVV-DCGEYTCKASNEYGSVSCTATLTVTVPGAE 1073 Score = 52.4 bits (120), Expect = 1e-04 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 1/98 (1%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 +++ P+FI + KL VT P P I W+ +++PS FDG Sbjct: 91 SKKEGHVPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDG 150 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + L+I E D G+Y CVASN G++ A + I Sbjct: 151 NDHSLIILFTKFE-DEGEYTCVASNEYGQAVCSASLKI 187 Score = 51.6 bits (118), Expect = 2e-04 Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 4/156 (2%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAK--STTKLKVE 1282 +V WY + ++ EKF + D TL+I TE+ Q YTC L+AK ++T K+ Sbjct: 912 EVNWYFEGKLVHSDEKFKCLQDQNTYTLVIHGVNTEEHQGAYTCEALNAKGNASTSAKLT 971 Query: 1283 VVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 VV+ ++ E + G + Q P +W + I + Sbjct: 972 VVKRAAPVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIRSSKY 1031 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 ++L I + + D G Y + N G +T+ Sbjct: 1032 VSTLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 1067 Score = 46.4 bits (105), Expect = 0.009 Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 1/95 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+ ++ P G +F C+V+ P + WF+ I S + V+TL Sbjct: 977 APVIKRRIEPLEVALGHLAKFTCEVQIAPNVRFQWFKAGREIYESDKCSIR-SSKYVSTL 1035 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I D G +TC A N G S T L V P Sbjct: 1036 EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 1070 Score = 45.6 bits (103), Expect = 0.015 Identities = 40/186 (21%), Positives = 69/186 (37%), Gaps = 7/186 (3%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXX 1538 P + PL + T E + + LT + V WY +GK + + K + Sbjct: 884 PVMLTPLVDTTAEEGDVVNLTSSITNAKE--VNWYFEGKLVHSDEKFKCLQDQNTYTLVI 941 Query: 1539 XXXXXXXX--XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C A N G TS + + ++ I + +G T + Sbjct: 942 HGVNTEEHQGAYTCEALNAKGNASTSAKLTVVKRAAPVIKRRIEPLEVALGHLAKFTCEV 1001 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 + P W+K G ++ + +I + + S + I + +YT +ASN G+ S Sbjct: 1002 QIAPNVRFQWFKAGREIYESDKCSIRSSKYVSTLEILRTQVVDCGEYTCKASNEYGSVSC 1061 Query: 1657 EVTLKV 1662 TL V Sbjct: 1062 TATLTV 1067 Score = 44.4 bits (100), Expect = 0.035 Identities = 57/213 (26%), Positives = 87/213 (40%), Gaps = 41/213 (19%) Query: 1016 IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 +P FI+++ + E+ DVA L V + + W G ++ P + Y F G+ L Sbjct: 97 VPVFIKEVSNAEISIGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSAD-YKFVFDGNDHSL 155 Query: 1075 YIRNTSVHDEGEYSCILRDE----SCTAEVTV--------------VE---------LPP 1107 I T DEGEY+C+ +E C+A + + VE PP Sbjct: 156 IILFTKFEDEGEYTCVASNEYGQAVCSASLKISSKGEGQKETEAEPVETFLEKFEGPCPP 215 Query: 1108 EIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTI----DGKKQK 1162 + + +G A FE + L + V WFK+ Q ++ TI DG Sbjct: 216 YFLKEFKPIHCARGLPAVFEYVVLGEPAPTVTWFKESK--QLCTNVYHTIIHNPDGSGTF 273 Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTV 1191 + + D +D+G Y C G S CTA L V Sbjct: 274 I-VNDPQREDSGLYVCRAENMWGESTCTAELLV 305 Score = 39.9 bits (89), Expect = 0.75 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 9/112 (8%) Query: 496 PVFEKPTSEEQSMAPI-FVEKLRP----KHTPDGSTVQFECQVEGYPRPQIT-WFRQTAI 549 P E P + + P+ FV++++ + P GS+ FEC V P IT W + + Sbjct: 1244 PPDEAPFTYQLKAVPLKFVKEIKDIVLTEAEPVGSSAIFECLVS--PSTAITSWMKDGSS 1301 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I+ S + D + L I +V DAG +TCV + +ST +L+VE Sbjct: 1302 IRESPKHRFIADGKD-RKLHIMDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 1352 Score = 39.9 bits (89), Expect = 0.75 Identities = 22/92 (23%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV----- 1658 V+W+KN KL + I+++ KT + I+E+ S+ + + + +++++V Sbjct: 1748 VVWFKNDAKLHTSRTVLISSEGKTHKLEIREVTLDDISQIRAQVKDLSSSANLKVLEADP 1807 Query: 1659 --TLKVYDKPSKPEGPVIMR-EISRESVTIEW 1687 T+K++DK + +I++ E+S++ V ++W Sbjct: 1808 YFTVKLHDKTGVEKDEIILKCEVSKD-VPVKW 1838 Score = 39.5 bits (88), Expect = 0.99 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 4/91 (4%) Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 +SN +I +GD ++ + GIP P++ W+ G L +Y + I Sbjct: 104 VSNAEIS----IGDVAKLSVTVTGIPKPKIQWFFKGVMLTPSADYKFVFDGNDHSLIILF 159 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 K +YT ASN G + +LK+ K Sbjct: 160 TKFEDEGEYTCVASNEYGQAVCSASLKISSK 190 Score = 36.3 bits (80), Expect = 9.2 Identities = 18/31 (58%), Positives = 20/31 (64%) Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 PED GT+T VA NA G SST L + AP S Sbjct: 1 PEDEGTYTFVANNAMGQVSSTANLRLAAPES 31 >UniRef50_Q59E65 Cluster: CG33519-PB; n=5; Sophophora|Rep: CG33519-PB - Drosophila melanogaster (Fruit fly) Length = 4129 Score = 193 bits (471), Expect = 4e-47 Identities = 308/1315 (23%), Positives = 525/1315 (39%), Gaps = 158/1315 (12%) Query: 538 RPQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596 +P W R P + F++ + +D++ LV + V PEDAG +TCVA+ + G S + Sbjct: 1147 KPVFQWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSA 1206 Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 EL V+ G+ T+ E PT + + G +LE + Sbjct: 1207 ELSVQ------GAIQTLNR--------------EPEKPTLVIEHREANASIGGSAILELQ 1246 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 P+P + W GE I D+ E + M L I NV G YT+ A+N Sbjct: 1247 CKGFPKPAVQWKHDGEVIQVDDRHKFMYEDEESMS---LVIKNVDTVDAGVYTIEAINEL 1303 Query: 717 GEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 G+ I L +K PP+ I+ + + GE++ + +V G P+PT+ N K V Sbjct: 1304 GQDESSINLVVKA----PPK-IKKITDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVT 1358 Query: 777 A-----LPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 A + + S G + +++ K++K G Y++KA N +++TS + ++ Sbjct: 1359 AESNVKISSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATND--LSQTSEYWSCTVKSK-- 1414 Query: 830 AEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGEN 887 P+ + F+ E EK +++ R+ P +TWY + EI T + DG Sbjct: 1415 ---PVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNA 1471 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT-- 945 L IT + +D+G Y A+N G ++ ++ I + H K+ EG + Sbjct: 1472 YTLKITGA-TRVDAGKYTVKATNEHGSATSSTQLLI--KCAPEFTHKLKNITVAEGDSNV 1528 Query: 946 -VILECQTSHTVSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXXXXDVGVIKC-IV 1001 +++ KWY + EI D R ++EG G C I+ Sbjct: 1529 ELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRH-VEEGNDFKLIMNQVATNMQGNYTCKIM 1587 Query: 1002 KD--QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDG-EIIK 1057 D + +V P+ R L++ EV+E LEVE+ SE A + W +DG EI + Sbjct: 1588 NDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYE 1647 Query: 1058 PKKNKYDFE-KRGHIRKLYIRNTSVHDEGEY-------------SC---ILRDESCTAEV 1100 + K + +R L + D G Y +C +L E+ + E Sbjct: 1648 DARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQ 1707 Query: 1101 TV-------VELP-----PEII-TRLQNQKVNKGNKATFEIELT---KGDALVRWFKDGS 1144 TV E P PEI+ + Q + +E+ T K +A+ W+ DG Sbjct: 1708 TVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAI--WYHDGK 1765 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE 1204 I H +T+DG KL++ DL DAGEY V N K E S++ + Sbjct: 1766 PITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQN-KVGEKSHQGELSLSGIAEYRK 1824 Query: 1205 FILVPANTDAYLTVEIPDETLDVTWYKKKS-----VIEDTEKFTLISDVKKRTLIIRKCT 1259 IL + V D+ + + +++D + ++VK + + +K Sbjct: 1825 PILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLK--VDKKDA 1882 Query: 1260 EDDQCEYTCVL--LDA--KSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVD 1310 E+ +YTC L L+A K + + +++V ++V D + I +D L Sbjct: 1883 ENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEISGLNDTKCLPG 1942 Query: 1311 --------YQAFPQPNDEWIVNSKIIKKCKHTK----PSIDSKSASLTIKKVENTDAGIY 1358 QA P+P W ++ + C H +D+ L + V + G Y Sbjct: 1943 DTICFEALVQANPKPKVSWTRGNENL--CNHENCEVIADVDADKYRLVFQSVSPCEDGKY 2000 Query: 1359 KLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDS----SSINICWDEPENTGNSTII 1413 + N+ G A V+ N+ +L +KP+ +P I S+ + P T Sbjct: 2001 TITATNSEGRAAVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKD 2060 Query: 1414 YYVVEYQEIDT--TEWISVKNITKTQT-------SIQNLKTNSSYRFRAYAVNEVDISDA 1464 + Y+ I+ + + K TK T I++ + N + A NE+ ++ A Sbjct: 2061 DKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKA 2120 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 +K+ + +P+ K L N + E + L C G P P V W +DG ++K Sbjct: 2121 P-----FKLAMLS--LAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVK 2173 Query: 1524 TAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 +++ + YK I N HGE C V ++ + + + Sbjct: 2174 PSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLK 2233 Query: 1579 DI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELK 1636 I Q VG+ + A + G P PEV WYK+G L E N + + I + Sbjct: 2234 PITSQTVVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQ 2293 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEWKPPLDDGG 1695 + Y +N G +++ K SKP +++ S E ++ + Sbjct: 2294 PLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNP 2353 Query: 1696 LELTKYAIEKHE--PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 ++ HE PD + I + + + + I+K ++ VIAQNP G Sbjct: 2354 KPKLQWFHNGHEIKPDASH-IAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEG 2407 Score = 185 bits (451), Expect = 1e-44 Identities = 222/960 (23%), Positives = 383/960 (39%), Gaps = 103/960 (10%) Query: 599 IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 I+EA + D G E+ V D+L P S + + G I E + Sbjct: 1895 ILEAEIKDSGRYELKVKNKYGELVTSGWIDVLA--KPEISGLNDTKCLP-GDTICFEALV 1951 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 A P+P ++W E + EN V + D Y V + +V ++G YT+ A N EG Sbjct: 1952 QANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQ--SVSPCEDGKYTITATNSEG 2009 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 A++ L + ++P +++P +S + V V G P PTI W K++KP+ Sbjct: 2010 RAAVDFNLAVLV--EKPTFIVQP-ESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINY 2066 Query: 778 LPTKSDG--------DT-------HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 G DT S+ +K + D G YT A N G+ + + + Sbjct: 2067 EAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAM 2126 Query: 823 EEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 P F+ + + V + + L V +P+P++ W ++ + + PSE+I Sbjct: 2127 LSLA------PSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKI 2180 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--FVKHLQKSYE 939 + + + + + N DSG YK + SN G+ V + E++ F+K + S Sbjct: 2181 STNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPIT-SQT 2239 Query: 940 TEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX-XDVGV 996 G+ + LE Q + KWY + + I D GV Sbjct: 2240 VVVGEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGV 2299 Query: 997 IKCIVKDQE------TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVW 1049 KC++ ++ + +V KE+ P F+ +LQD E +++++ + + W Sbjct: 2300 YKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQW 2359 Query: 1050 ERDGEIIKPKKNKYDF-EKRGHIRKLYIRNTSVHDEGEYSCILRD-ESCTA--------- 1098 +G IKP + E + L I T+ D G Y I ++ E TA Sbjct: 2360 FHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAP 2419 Query: 1099 --EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLT 1155 + T E P+ ++ L++ ++G + V W KDG + + + +T Sbjct: 2420 KADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMT 2479 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTA-ILTVEEPSINFTLRLPEFILV 1208 DGK L I + D+G Y+C + N S C A + V +P + FT ++ + V Sbjct: 2480 CDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPPV-FTQKISDQQQV 2538 Query: 1209 PANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 N +A + V + D+ WY + I +EK+++ +D LI+ C + DQ Y Sbjct: 2539 FGN-NAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYK 2597 Query: 1268 CVL--LDAKSTTKLKVEVV--------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 C+ + K T+ ++++V PP + + I G +P+P Sbjct: 2598 CIASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEP 2657 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCG----HAD-- 1370 EW N + + I+ LTIK V D G Y R+ N G HA+ Sbjct: 2658 EVEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELF 2717 Query: 1371 ----------VEMNVTILDK------PSPPGK-PNILEIDSSSINICWDEPENTGNSTII 1413 +E T K P P + P I + + + W+ I Sbjct: 2718 YDSLDSQQKPLEDQYTDFKKYKKSGAPPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPI 2777 Query: 1414 YYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 Y +E ++ +W +++ + I+NL+ YRFR N+ +SD S T+ Y+ Sbjct: 2778 TYQIEMMDLPEGDWRTLRTGVRSCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYR 2837 Score = 172 bits (419), Expect = 8e-41 Identities = 236/1079 (21%), Positives = 410/1079 (37%), Gaps = 93/1079 (8%) Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT--LVIREV 573 L+ +G + E +V P +I WF+ I ++ D + L + Sbjct: 1611 LKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYYLTLNLA 1670 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG-I 632 EDAGT+ A N G +ST ++ V +++ + EG + Sbjct: 1671 RTEDAGTYEMKATNFIGETTSTCKVAVLT-----SEALSLEQTVTKTLIATTEEPEEGAV 1725 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P Q+ E + E IP+P+ W G+ I PD++ ++ ++ D + Sbjct: 1726 PEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYK-- 1783 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIE--PLKSMIVRQG 749 L++ ++ G Y VV N+ GE S L + E P + + LK + V +G Sbjct: 1784 --LEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841 Query: 750 ESVILSAQVVGNPRPTITWCKNNKP------VKALPTKSDGD------THSITILKPKKV 797 + V +P P I K+ +P VK K D + T ++ IL+ ++ Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILE-AEI 1900 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 KD G Y LK +N G TS I V E I+ + TI A V Sbjct: 1901 KDSGRYELKVKNKYGELVTSGWIDVLAKPE--------ISGLNDTKCLPGDTICFEALVQ 1952 Query: 858 RNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 NP P ++W R NE + E + + D + LV +V S + G Y A+NS G++ Sbjct: 1953 ANPKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSV-SPCEDGKYTITATNSEGRA 2011 Query: 916 SHGARVTIDVEKVTFV--KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS----- 968 + + + VEK TF+ Q ++ T +L + +W+ + K I+ Sbjct: 2012 AVDFNLAVLVEKPTFIVQPESQSIHDYRPVSTKVL-VHGVPLPTIEWFKDDKPINYEAIN 2070 Query: 969 --GMDH---REIIQEGR---XXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETI 1016 G D +E ++G DVG C+ ++ + L + Sbjct: 2071 KPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLA 2130 Query: 1017 PEFIRKLQD-FEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 P F++KL + +V + + +LE ++ S V W +DG+ +KP ++ + KL Sbjct: 2131 PSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKL 2190 Query: 1075 YIRNTSVHDEGEYSCILRDES------CTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 I + +D G Y I+ + C V E+ P+ + + +Q V G E Sbjct: 2191 EINSCQPNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEA 2250 Query: 1129 ELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCT 1186 ++T A V+W+KDG ++ S I Q I D DAG Y C + N K Sbjct: 2251 QVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIAN-KGG 2309 Query: 1187 AILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDETL-----DVTWYKKKSVIE-D 1238 I V + I P F+ L A++ V++ + + + W+ I+ D Sbjct: 2310 EIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPD 2369 Query: 1239 TEKFTLISDV-KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP---------- 1287 ++ + +LII K D Y + + + +T K ++ P Sbjct: 2370 ASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEA 2429 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P+ V R+ G ++ L + + P P W + + + + D K LTI Sbjct: 2430 PQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTI 2489 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 K E D+G Y L N G N + PP + P Sbjct: 2490 KPAEAADSGNYTCLLANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTV 2549 Query: 1408 GNSTI--IYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 + + + + I +E S+KN + N + ++ A N Sbjct: 2550 SGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDIT 2609 Query: 1465 SETTEYYKVIKE-TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + IK+ ++ + P K + + + T G P+P+V W+++ +KL Sbjct: 2610 QGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKL 2668 Score = 139 bits (336), Expect = 9e-31 Identities = 106/411 (25%), Positives = 181/411 (44%), Gaps = 35/411 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATL 568 P+FV +L+ + +G V+ + +V G P+P++ WF IKP + + + DN ++L Sbjct: 2326 PVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSL 2385 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 +I + P D+G + +A+N G +S +L V AP +D + Sbjct: 2386 IIEKTAPGDSGLYEVIAQNPEGSTASKAKLYV-APKADETATEEA--------------- 2429 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 P F + DEG +++L ++ P P++ W G + P+E + + + Sbjct: 2430 -----PQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDG-K 2483 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 H+ L I + G YT + N GE S ++ K PP + + Sbjct: 2484 HI---GLTIKPAEAADSGNYTCLLANPLGEDSSACNANVRKVYK-PPVFTQKISDQQQVF 2539 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G + + V G P P + W +KP+ + K+DGD H + + +K D+GVY Sbjct: 2540 GNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEK-GDQGVYKC 2598 Query: 806 KAENSEG--IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 A N EG I + I E +EPP+F+ + + + E K A T P P Sbjct: 2599 IASNREGKDITQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPE 2658 Query: 864 ITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAG 913 + W++N++ + PS+ + + + L I NV +E D G Y C N G Sbjct: 2659 VEWFKNDQKLFPSDRFLIDIEPNGLLRLTIKNV-TEYDVGRYSCRIFNPYG 2708 Score = 135 bits (327), Expect = 1e-29 Identities = 202/941 (21%), Positives = 363/941 (38%), Gaps = 101/941 (10%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 L + + K + EE ++ I + +H+ + +++E G P+P+ W+ Sbjct: 1705 LEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDG 1764 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 I P + + D D+ L ++ + DAG + V +N G S H Sbjct: 1765 KPITPDKHTAITVDGDHY-KLEVQSLDLVDAGEYKVVVQNKVGEKS-------------H 1810 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP--KAQYVDEGSDILLECRLVAIPEPDI 665 E+++ + I E P ++ P K V++G + A P P+I Sbjct: 1811 QGELSL------------SGIAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEI 1858 Query: 666 AWLFKGEEIVPDENISVAI-----ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 L G+ +V N+ + + E+ + Y L I + G Y + N+ GE Sbjct: 1859 VLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGE-- 1916 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----- 775 +V P+ I L G+++ A V NP+P ++W + N+ + Sbjct: 1917 --LVTSGWIDVLAKPE-ISGLNDTKCLPGDTICFEALVQANPKPKVSWTRGNENLCNHEN 1973 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + D D + + +D G YT+ A NSEG A + V E P F Sbjct: 1974 CEVIADVDADKYRLVFQSVSPCED-GKYTITATNSEGRAAVDFNLAV------LVEKPTF 2026 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-----FDGENIEL 890 I + + ++ + + V P+P+I W+++++ I+ E I + + E+ + Sbjct: 2027 IVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPIN-YEAINKPGKDKLYAKEDTKK 2085 Query: 891 VITNVDS--------EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 ++S E D G Y CVA+N G + ++ + +FVK L + + + Sbjct: 2086 GTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAPSFVKKLDNALDVLQ 2145 Query: 943 GKTVILEC--QTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKC 999 G+ ++LEC S + +W + E+ + +I D G K Sbjct: 2146 GEPLVLECCVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLVKLEINSCQPNDSGAYKL 2205 Query: 1000 IVKDQ--ETSTMLVV----KETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERD 1052 I+ + E + V +E P+F++ + V + LE ++ A +V W +D Sbjct: 2206 IISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVTGFPAPEVKWYKD 2265 Query: 1053 GEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-VTVVELPPE-- 1108 G +++P + G I L I D G Y C++ ++ E V+ VE+ P+ Sbjct: 2266 GMLLRPSPEINFINSPNGQI-GLIIDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKES 2324 Query: 1109 ---IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQ-FSNHIQLTID-GKKQK 1162 + LQ+ +G +I++ ++WF +G EI+ ++HI + + Sbjct: 2325 KPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSS 2384 Query: 1163 LKIYDCDLDDAGEYSCEVGNSK-CTA----ILTVEEPSINFTLRLPEFIL----VPANTD 1213 L I D+G Y N + TA + + T P+F+ V A+ Sbjct: 2385 LIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEG 2444 Query: 1214 AYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 L + P + +V W K + E+ + D K L I+ D YTC+L Sbjct: 2445 QELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLL 2504 Query: 1271 L----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + S V V PP + + G++ + V P P+ EW K Sbjct: 2505 ANPLGEDSSACNANVRKVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDK 2564 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 I K + D L + E D G+YK N G Sbjct: 2565 PIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREG 2605 Score = 132 bits (318), Expect = 1e-28 Identities = 114/456 (25%), Positives = 185/456 (40%), Gaps = 47/456 (10%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D Y + EK+ V KP + M P F++ + + G ++ E QV G Sbjct: 2199 DSGAYKLIISNPHGEKVALCAVAVKP----EEMQPKFLKPITSQTVVVGEPLKLEAQVTG 2254 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 +P P++ W++ +++PS + + L+I P DAG + C+ N G Sbjct: 2255 FPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGG----E 2310 Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 E + + + S+ + I + KPK Q+ G +I + Sbjct: 2311 IEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDA 2370 Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 +AI E PD + S+ IE G Y V+A N Sbjct: 2371 SHIAIVEN------------PDNSSSLIIE-------------KTAPGDSGLYEVIAQNP 2405 Query: 716 EG----EASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 EG +A L + K +T +E PQ + L+ + +G+ ++LSA + NP P + W K Sbjct: 2406 EGSTASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSK 2465 Query: 771 NN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 + P + L DG +TI KP + D G YT N G E S+ Sbjct: 2466 DGVTLTPNERLLMTCDGKHIGLTI-KPAEAADSGNYTCLLANPLG--EDSSACNAN--VR 2520 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 + +PP+F + + K+ V+ P P + WY ++ I SE + DG++ Sbjct: 2521 KVYKPPVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDH 2580 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 L++ N + D G YKC+ASN GK R+ I Sbjct: 2581 HMLIVNNCEKG-DQGVYKCIASNREGKDITQGRLDI 2615 Score = 129 bits (311), Expect = 9e-28 Identities = 267/1222 (21%), Positives = 460/1222 (37%), Gaps = 138/1222 (11%) Query: 634 PTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDMHMY 691 P K +++Y+ E ++ + R+ A PE + W EI + D +V+ SD + Y Sbjct: 1415 PVIVKNFESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVS--SDGNAY 1472 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 LKIT + G YTV A N G A+ L IK P+ LK++ V +G+S Sbjct: 1473 --TLKITGATRVDAGKYTVKATNEHGSATSSTQLLIKCA----PEFTHKLKNITVAEGDS 1526 Query: 752 -VILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLK 806 V L V PRP W + + +G+ + I+ +G YT K Sbjct: 1527 NVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKL-IMNQVATNMQGNYTCK 1585 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G E + V+TV N +P + + + V+E + L V P I W Sbjct: 1586 IMNDYGKLEDNCVVTV------NCKPKVK-RGLKNVEVQEGKSFTLEVEVYSEPEAKIKW 1638 Query: 867 YRNNEIISPSETITQNFDGENIE--LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI- 923 +++ I I + D + IE + N+ D+G Y+ A+N G+++ +V + Sbjct: 1639 FKDGHEIYEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATNFIGETTSTCKVAVL 1698 Query: 924 -----DVEKVTFVKHLQKSYETEEG----------------KTVILECQTSHTVSTK--- 959 +E+ + + E EEG ++V L+ + T K Sbjct: 1699 TSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEA 1758 Query: 960 -WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--------ETSTML 1010 WYH+ K I+ H I +G D G K +V+++ E S Sbjct: 1759 IWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSG 1818 Query: 1011 VVKETIPEFIRK--LQDFEVKEKDVAILEVEINSETA-DVVWERDGEII------KPKKN 1061 + + P + L+D +V + D V ++ A ++V +DG+ + K K + Sbjct: 1819 IAEYRKPILTQGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVD 1878 Query: 1062 KYDFEKR--GHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQ 1116 K D E + L I + D G Y +++ E T+ V PEI + L + Sbjct: 1879 KKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWIDVLAKPEI-SGLNDT 1937 Query: 1117 KVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNH----IQLTIDGKKQKLKIYDCDLD 1171 K G+ FE + V W + G+E NH + +D K +L Sbjct: 1938 KCLPGDTICFEALVQANPKPKVSWTR-GNE-NLCNHENCEVIADVDADKYRLVFQSVSPC 1995 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL------ 1225 + G+Y+ NS+ A + ++ + P FI+ P + + + + L Sbjct: 1996 EDGKYTITATNSEGRAAVDF---NLAVLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPL 2052 Query: 1226 -DVTWYKKKSVIE-------DTEKFTLISDVKKRT------LIIRKCTEDDQCEYTCVLL 1271 + W+K I +K D KK T L I+ E+D YTCV Sbjct: 2053 PTIEWFKDDKPINYEAINKPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVAT 2112 Query: 1272 DAKSTTK--LKVEVVEFPPKIVD-YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 + TK K+ ++ P V + + +G + L P P +W+ + + Sbjct: 2113 NEIGVTKAPFKLAMLSLAPSFVKKLDNALDVLQGEPLVLECCVDGSPLPTVQWLKDGDEV 2172 Query: 1329 KKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 K + K S + L I + D+G YKL + N G V + KP Sbjct: 2173 KPSESIKISTNPDGLVKLEINSCQPNDSGAYKLIISNPHGEKVALCAVAV--KPEEMQPK 2230 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVE---YQEIDTTEWISVKNITKTQTSIQNLK 1444 + I S ++ + EP + E Y++ N + L Sbjct: 2231 FLKPITSQTVVV--GEPLKLEAQVTGFPAPEVKWYKDGMLLRPSPEINFINSPNGQIGLI 2288 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 +++ A + + E KV K P L++ ++ +++ Sbjct: 2289 IDAAQPLDAGVYKCLIANKGGEIEGVSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIK 2348 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATY------ENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 G P+PK+ W+ +G ++K + +N Y+ IA N G Sbjct: 2349 VVGNPKPKLQWFHNGHEIKPDASHIAIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGS 2408 Query: 1559 VETSCVVGIQQKPVITISNED---IKQKHKV----GDEWLVTAVIEGIPPPEVIWYKNGN 1611 + + + K T + E + V G E +++A P PEVIW K+G Sbjct: 2409 TASKAKLYVAPKADETATEEAPQFVSALRDVNADEGQELVLSAPFISNPMPEVIWSKDGV 2468 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 L ++ +T K + IK + + S YT +N G S V K KP Sbjct: 2469 TLTPNERLLMTCDGKHIGLTIKPAEAADSGNYTCLLANPLGEDSSACNANV-RKVYKP-- 2525 Query: 1672 PVIMREISRESVTI--EWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 PV ++IS + K P+ G+ +L Y +K P + ++ + + D D Sbjct: 2526 PVFTQKISDQQQVFGNNAKIPVTVSGVPYPDLEWYFQDKPIPKSEKY-SIKN-DGDHHML 2583 Query: 1727 CIQKLNENCEYMFRVIAQNPVG 1748 + + + +++ IA N G Sbjct: 2584 IVNNCEKGDQGVYKCIASNREG 2605 Score = 128 bits (309), Expect = 2e-27 Identities = 222/1026 (21%), Positives = 407/1026 (39%), Gaps = 114/1026 (11%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHS 788 + P V++ LKS+ V GE+ Q P +TW K+NKP++ T++ +S Sbjct: 926 DKPVVVKMLKSVQVEPGETAHFEIQFKDQPG-LVTWLKDNKPLEDRLADRITQTAAPMNS 984 Query: 789 ITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITV-----EEPTEENAEPPLFINRFQEI 842 + +K D G YT++A+++ SA + V + T+ N EP ++ ++ Sbjct: 985 YRLDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNTEPAFLVS-LKDA 1043 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI---ELVITNVDSE 898 + E + + ++ +P P + +Y++ EI+ ++ I D + + ELVI +V + Sbjct: 1044 EMIENTLFRFMVKIIGDPKPRVKFYKDEKEILETNDRIQIIRDKDYLGFYELVIADVQ-K 1102 Query: 899 IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST 958 D+G Y C A+N G+++ A T +K F + E K V Sbjct: 1103 TDAGTYSCKATNKHGEANCEAIATTVEDKNPFGALSGQILPAGE-KPVF----------- 1150 Query: 959 KWYHNKKEISGMDHREII--QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012 +W N +E + +++ ++ D G+ C+ + S L V Sbjct: 1151 QWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAGIYTCVAQTSTGNISCSAELSV 1210 Query: 1013 KETIPEFIRKLQD----FEVKEKDV-----AILEVEINSETADVV-WERDGEIIK-PKKN 1061 + I R+ + E +E + AILE++ V W+ DGE+I+ ++ Sbjct: 1211 QGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRH 1270 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKV 1118 K+ +E + L I+N D G Y+ +E E + VV+ PP+ I ++ + Sbjct: 1271 KFMYEDEESM-SLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAPPK-IKKITDITC 1328 Query: 1119 NKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTID--GK---KQKLKIYDCDLDD 1172 + G EIE+ V+ +G ++ ++++++ GK K +++ + L Sbjct: 1329 SAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKISSSSIGKSLEKVVVEVKEIKLSQ 1388 Query: 1173 AGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDV 1227 AG YS + N TV+ + E+I + +TV I + Sbjct: 1389 AGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEYI-HGEKENVQMTVRIDAYPEAKL 1447 Query: 1228 TWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVE 1285 TWY ++ I+ T+ K+T+ SD TL I T D +YT + S T +++ Sbjct: 1448 TWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAGKYTVKATNEHGSATSSTQLLIK 1507 Query: 1286 FPPKIVDYEREYRIKRG-SDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSA 1343 P+ + + G S+V L+V A+P+P+ +W ++ +I +K + + Sbjct: 1508 CAPEFTHKLKNITVAEGDSNVELVVGVDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDF 1567 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINI--- 1399 L + +V G Y ++ N+ G + VT+ KP G N+ + S + Sbjct: 1568 KLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVNCKPKVKRGLKNVEVQEGKSFTLEVE 1627 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 + EPE + + Y++ + I ++ +T + + A N Sbjct: 1628 VYSEPEAKIKWFKDGHEI-YEDARIKISRDTQRIENYYLTLNLARTEDAGTYEMKATN-- 1684 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE--------------------DI 1499 I + + T + + E TV K L T EP E + Sbjct: 1685 FIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEEGAVPEIVHVDVFQQHSYESVPL 1744 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 + I G+P+P+ WY DGK + TA + YK + N Sbjct: 1745 KYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHYKLEVQSLDLVDAGEYKVVVQNK 1804 Query: 1556 HGEVETS---CVVGIQQ--KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 GE + GI + KP++T +K K GD+ V P PE++ K+ Sbjct: 1805 VGEKSHQGELSLSGIAEYRKPILT-QGPGLKDIKVNKGDKVCEPVVFTADPAPEIVLLKD 1863 Query: 1610 GNKLENDKEYNITTKEK---------TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 G + + +K T + I E + S +Y ++ N G + Sbjct: 1864 GQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIKDSGRYELKVKNKYGELVTSGWI 1923 Query: 1661 KVYDKP 1666 V KP Sbjct: 1924 DVLAKP 1929 Score = 118 bits (284), Expect = 2e-24 Identities = 263/1254 (20%), Positives = 483/1254 (38%), Gaps = 160/1254 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP--SQDFQMYYDDDNVAT 567 P+ V+ L+ G T FE Q + P +TW + ++ + N Sbjct: 928 PVVVKMLKSVQVEPGETAHFEIQFKDQPG-LVTWLKDNKPLEDRLADRITQTAAPMNSYR 986 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXXXXXXA 626 L I+ DAGT+T A++A+ + + +L V +AP D T Sbjct: 987 LDIKNCSETDAGTYTIRAQSASETTTVSAQLAVGQAPGHDETKTNT-------------- 1032 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 P F K + E + +++ P+P + + +K E+ + + N + I Sbjct: 1033 ------EPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKF-YKDEKEILETNDRIQIIR 1085 Query: 687 DM-HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 D ++ L I +V+K GTY+ A N+ GEA+ + T E + P L I Sbjct: 1086 DKDYLGFYELVIADVQKTDAGTYSCKATNKHGEANCEAI--ATTVEDKNP--FGALSGQI 1141 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSIT-ILKPKKVKDEG 801 + GE +P W +N + P + D S+ + + K +D G Sbjct: 1142 LPAGE------------KPVFQWKRNGEEFDPEERFKVLFGEDEDSLALVFQHVKPEDAG 1189 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEE-NAEP--PLFINRFQEITVKEKGTIKLVARVTR 858 +YT A+ S G SA ++V+ + N EP P + +E G+ L + Sbjct: 1190 IYTCVAQTSTGNISCSAELSVQGAIQTLNREPEKPTLVIEHREANASIGGSAILELQCKG 1249 Query: 859 NPVPSITWYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P++ W + E+I + + D E++ LVI NVD+ +D+G Y A N G+ Sbjct: 1250 FPKPAVQWKHDGEVIQVDDRHKFMYEDEESMSLVIKNVDT-VDAGVYTIEAINELGQDE- 1307 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREI 975 + + + V+ +K + G+T+ +E + + + +N K+++ + +I Sbjct: 1308 -SSINLVVKAPPKIKKI-TDITCSAGETIKMEIEVEGFPQPTVQVTNNGKDVTAESNVKI 1365 Query: 976 IQEGRXXXXXXXXXXXXDVGV-------IKCIVKDQETST-MLVVKETIPEFIRKLQ-DF 1026 ++ + IK +TS ++ P ++ + ++ Sbjct: 1366 SSSSIGKSLEKVVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKSKPVIVKNFESEY 1425 Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 EK+ + V I++ A + W D IK +KY G+ L I + D G Sbjct: 1426 IHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATRVDAG 1485 Query: 1086 EYSCILRDE--SCTAEV-TVVELPPEIITRLQNQKVNKGNKATFEIELTKG-DALVR--- 1138 +Y+ +E S T+ +++ PE +L+N V +G+ +EL G DA R Sbjct: 1486 KYTVKATNEHGSATSSTQLLIKCAPEFTHKLKNITVAEGDS---NVELVVGVDAYPRPHA 1542 Query: 1139 -WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192 W+ DG EI + N + +G KL + + G Y+C++ G + ++TV Sbjct: 1543 KWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNMQGNYTCKIMNDYGKLEDNCVVTVN 1602 Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKK 1250 +P + L+ E V L VE+ E + W+K I + + + D ++ Sbjct: 1603 CKPKVKRGLKNVE---VQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQR 1659 Query: 1251 -----RTLIIRKCTED----------------DQCEYTCVLLDA----KSTTKLKVEVVE 1285 TL + + TED C+ + +A ++ TK + E Sbjct: 1660 IENYYLTLNLAR-TEDAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTE 1718 Query: 1286 FP-----PKIVDYEREYRIKRGSDVTLLVDYQA--FPQPNDEWIVNSKIIKKCKHTKPSI 1338 P P+IV + ++ V L + A P+P W + K I KHT ++ Sbjct: 1719 EPEEGAVPEIVHVD-VFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITV 1777 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-----LDKPSPPGKPNILEID 1393 D L ++ ++ DAG YK+ ++N G + +++ KP P + +I Sbjct: 1778 DGDHYKLEVQSLDLVDAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIK 1837 Query: 1394 -SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 + +C + I + + Q + T + +K + K ++ + Sbjct: 1838 VNKGDKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLK-VDKKDAENGLVQYTCTLNIL 1896 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP----LKNITTEPNEDIELTCIFGGV 1508 + + + +Y +++ I + KP L + P + I + Sbjct: 1897 EAEIKDSGRYELKVKNKYGELVTSGWID--VLAKPEISGLNDTKCLPGDTICFEALVQAN 1954 Query: 1509 PQPKVTWYRDGKKL------KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 P+PKV+W R + L + ++ Y A N G Sbjct: 1955 PKPKVSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVD 2014 Query: 1563 CVVGI-QQKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG--------N 1611 + + +KP ++ ++ I V + LV G+P P + W+K+ N Sbjct: 2015 FNLAVLVEKPTFIVQPESQSIHDYRPVSTKVLV----HGVPLPTIEWFKDDKPINYEAIN 2070 Query: 1612 KLENDKEY-NITTKEKT----SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 K DK Y TK+ T SV+ IK + + YT A+N G + L Sbjct: 2071 KPGKDKLYAKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKL 2124 Score = 118 bits (284), Expect = 2e-24 Identities = 113/475 (23%), Positives = 202/475 (42%), Gaps = 54/475 (11%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T + P V + R + G + E Q +G+P+P + W +I+ + Y+ Sbjct: 1216 TLNREPEKPTLVIEHREANASIGGSAILELQCKGFPKPAVQWKHDGEVIQVDDRHKFMYE 1275 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 D+ +LVI+ V DAG +T A N G S+ L+V+AP ++T Sbjct: 1276 DEESMSLVIKNVDTVDAGVYTIEAINELGQDESSINLVVKAP--PKIKKITDITCSAGET 1333 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 ++ EG P +P Q + G D+ E + + +I Sbjct: 1334 IKMEIEV-EGFP-----QPTVQVTNNGKDVTAESNVK----------------ISSSSIG 1371 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 ++E V+++ +K Q G Y++ A N + S +K+ P +++ Sbjct: 1372 KSLEK------VVVEVKEIKLSQAGNYSIKATNDLSQTSEYWSCTVKS----KPVIVKNF 1421 Query: 742 KSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKK 796 +S + + E+V ++ ++ P +TW + +K +K SDG+ +++ I + Sbjct: 1422 ESEYIHGEKENVQMTVRIDAYPEAKLTWYHDETEIKITDSKYTVSSDGNAYTLKITGATR 1481 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGTIKLVAR 855 V D G YT+KA N G A +S + ++ P F ++ + ITV E ++LV Sbjct: 1482 V-DAGKYTVKATNEHGSATSSTQLLIK-------CAPEFTHKLKNITVAEGDSNVELVVG 1533 Query: 856 VTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V P P WY + EI +G + +L++ V + + G+Y C N GK Sbjct: 1534 VDAYPRPHAKWYIDGIEIDEKRNDFRHVEEGNDFKLIMNQVATNM-QGNYTCKIMNDYGK 1592 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEI 967 VT++ + VK K+ E +EGK+ LE + + KW+ + EI Sbjct: 1593 LEDNCVVTVNCKPK--VKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEI 1645 Score = 107 bits (258), Expect = 3e-21 Identities = 267/1243 (21%), Positives = 455/1243 (36%), Gaps = 144/1243 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD-MHMYC 692 P + K V EG LE + + PE I W G EI D I ++ ++ + Y Sbjct: 1605 PKVKRGLKNVEVQEGKSFTLEVEVYSEPEAKIKWFKDGHEIYEDARIKISRDTQRIENYY 1664 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE----------------KEPPQ 736 L + + GTY + A N GE + + + T E +EP + Sbjct: 1665 LTLNLARTE--DAGTYEMKATNFIGETTSTCKVAVLTSEALSLEQTVTKTLIATTEEPEE 1722 Query: 737 --VIEPLKSMIVRQG--ESVILSAQVV--GNPRPTITWCKNNKPV---KALPTKSDGDTH 787 V E + + +Q ESV L +V+ G P+P W + KP+ K DGD + Sbjct: 1723 GAVPEIVHVDVFQQHSYESVPLKYEVIATGIPKPEAIWYHDGKPITPDKHTAITVDGDHY 1782 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 + + V D G Y + +N G +++ E ++I V + Sbjct: 1783 KLEVQSLDLV-DAGEYKVVVQNKVGEKSHQGELSLSGIAEYRKPILTQGPGLKDIKVNKG 1841 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE-------LVITNVDSEI- 899 + T +P P I ++ + + + + D ++ E + +++EI Sbjct: 1842 DKVCEPVVFTADPAPEIVLLKDGQPVVETNNVKLKVDKKDAENGLVQYTCTLNILEAEIK 1901 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVS 957 DSG Y+ N G+ IDV + L + + G T+ E Q + Sbjct: 1902 DSGRYELKVKNKYGELVTSG--WIDVLAKPEISGLNDT-KCLPGDTICFEALVQANPKPK 1958 Query: 958 TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX--DVGVIKCIVKDQETSTM----LV 1011 W + + ++ E+I + + G + E L Sbjct: 1959 VSWTRGNENLCNHENCEVIADVDADKYRLVFQSVSPCEDGKYTITATNSEGRAAVDFNLA 2018 Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII------KPKKNK-Y 1063 V P FI + + + + +V ++ + W +D + I KP K+K Y Sbjct: 2019 VLVEKPTFIVQPESQSIHDYRPVSTKVLVHGVPLPTIEWFKDDKPINYEAINKPGKDKLY 2078 Query: 1064 DFE--KRG--HIRK-LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQ 1114 E K+G I L I++ +D G Y+C+ +E ++ ++ L P + +L Sbjct: 2079 AKEDTKKGTDQIESVLDIKSFRENDVGAYTCVATNEIGVTKAPFKLAMLSLAPSFVKKLD 2138 Query: 1115 NQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCD 1169 N V +G E G L V+W KDG E++ S I+++ DG KL+I C Sbjct: 2139 NALDVLQGEPLVLEC-CVDGSPLPTVQWLKDGDEVKPSESIKISTNPDGLV-KLEINSCQ 2196 Query: 1170 LDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILV---PANTDAYLTVEI 1220 +D+G Y + N + C + EE F + +V P +A +T Sbjct: 2197 PNDSGAYKLIISNPHGEKVALCAVAVKPEEMQPKFLKPITSQTVVVGEPLKLEAQVT-GF 2255 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLLDAKSTTK- 1278 P +V WYK ++ + + I+ + LII D Y C++ + + Sbjct: 2256 PAP--EVKWYKDGMLLRPSPEINFINSPNGQIGLIIDAAQPLDAGVYKCLIANKGGEIEG 2313 Query: 1279 -LKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK 1335 KVE+V E P V ++ G V + + P+P +W N IK Sbjct: 2314 VSKVEIVPKESKPVFVAELQDASSIEGFPVKMDIKVVGNPKPKLQWFHNGHEIKPDASHI 2373 Query: 1336 PSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393 +++ S+SL I+K D+G+Y++ +N G + + + K + Sbjct: 2374 AIVENPDNSSSLIIEKTAPGDSGLYEVIAQNPEGSTASKAKLYVAPKADETATEEAPQFV 2433 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQT--------SIQNLK 1444 S+ ++ DE + S + I + + +++ N T +I+ + Sbjct: 2434 SALRDVNADEGQELVLSAPFISNPMPEVIWSKDGVTLTPNERLLMTCDGKHIGLTIKPAE 2493 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 S + N + ++ KV K P + + + + ++ Sbjct: 2494 AADSGNYTCLLANPLGEDSSACNANVRKVYKP-----PVFTQKISDQQQVFGNNAKIPVT 2548 Query: 1505 FGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 GVP P + WY K + K+ K + +N YKCIA N G+ Sbjct: 2549 VSGVPYPDLEWYFQDKPIPKSEKYSIKNDGDHHMLIVNNCEKGDQGVYKCIASNREGKDI 2608 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGD----EWLV---TAVIEGIPPPEVIWYKNGNKL 1613 T + I + +E K+GD E +V TA G P PEV W+KN KL Sbjct: 2609 TQGRLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKL 2668 Query: 1614 ENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGTSSVEVTL----------- 1660 + I E ++R IK + +Y+ N G L Sbjct: 2669 FPSDRFLIDI-EPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELFYDSLDSQQKP 2727 Query: 1661 --------KVYDKPSKP----EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 K Y K P EGP+I R R + + W P + Y IE + Sbjct: 2728 LEDQYTDFKKYKKSGAPPPLSEGPIISRMTDR-GLLLSWNPSVPLTPRYPITYQIEMMDL 2786 Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 W + R I+ L +Y FRV +N G S+ Sbjct: 2787 PEGDWRTLRTGVRSC-ACDIRNLEPFRDYRFRVRVENKFGVSD 2828 Score = 76.6 bits (180), Expect = 7e-12 Identities = 46/155 (29%), Positives = 70/155 (45%), Gaps = 3/155 (1%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P P V W+KN L K I+ E S++R + Y + A N G + Sbjct: 3590 GDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVA 3649 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 + V P P+ P I E + + WK P DDG + Y+++ + + W V Sbjct: 3650 RCRIVVATLPDAPDSPEISANSGTE-ILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTV 3708 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 AD + D E Y + L N Y FR+ ++N +G+SE Sbjct: 3709 AD-NIDHEFYLLHDLQPNTNYQFRLASKNRIGWSE 3742 Score = 76.6 bits (180), Expect = 7e-12 Identities = 39/151 (25%), Positives = 72/151 (47%), Gaps = 2/151 (1%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P+P +W N ++ + K K S+D S L + + D G+YK+ N G Sbjct: 3592 PKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARC 3651 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KN 1432 + + P P P I + I + W +P + G+ST++ Y ++Y+ + W +V N Sbjct: 3652 RIVVATLPDAPDSPEISANSGTEILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTVADN 3711 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 I + +L+ N++Y+FR + N + S+ Sbjct: 3712 IDHEFYLLHDLQPNTNYQFRLASKNRIGWSE 3742 Score = 53.6 bits (123), Expect = 6e-05 Identities = 53/228 (23%), Positives = 92/228 (40%), Gaps = 16/228 (7%) Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKC 1550 + + EL G P+PK+T+Y D +++ T + Y+ Sbjct: 2898 DHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEA 2957 Query: 1551 IAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 +A N+HGE + I + P + +E K G + A + GIP PEV W+K+ Sbjct: 2958 VATNEHGEARQRVRLEIAEHPRFLKRPDETFIMARKNGR---IEAKLVGIPLPEVHWFKD 3014 Query: 1610 GNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS- 1667 + + I++ + V+ I + Y+I A N AG+ S VT+ + + Sbjct: 3015 WKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQ 3074 Query: 1668 ---KPEG--PVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 K G P + + R + L G +T +A+E+ DN Sbjct: 3075 YIYKTYGRHPYVRSKQLRYQDKYDIGDELGRGTQGITYHAVERSSGDN 3122 Score = 52.4 bits (120), Expect = 1e-04 Identities = 26/109 (23%), Positives = 49/109 (44%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 +L + + +S P+F++K+ +G +F GYP P++ WF+ + PS Sbjct: 2612 RLDIVNEIKKHSRSEPPVFLKKIGDCDIYEGMVAKFTACATGYPEPEVEWFKNDQKLFPS 2671 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 F + + + + L I+ V D G ++C N G EL ++ Sbjct: 2672 DRFLIDIEPNGLLRLTIKNVTEYDVGRYSCRIFNPYGDDICHAELFYDS 2720 Score = 52.4 bits (120), Expect = 1e-04 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 9/127 (7%) Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G Y VA N GEA + L+I E P+ ++ + ++ + A++VG P P Sbjct: 2953 GWYEAVATNEHGEARQRVRLEIA----EHPRFLKRPDETFIMARKNGRIEAKLVGIPLPE 3008 Query: 766 ITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W K+ KP+ + + D D + ++I +KD G+Y++ A N G TS + Sbjct: 3009 VHWFKDWKPIVDSSRIKISSYDPDIYVLSI-HDSIIKDGGLYSISARNIAGSISTSVTVH 3067 Query: 822 VEEPTEE 828 +EE ++ Sbjct: 3068 IEENEDQ 3074 Score = 49.6 bits (113), Expect = 0.001 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDM 688 EG PP F +KP+ + E + C V P+P + W FK + ++ + + I ++++ D Sbjct: 3561 EGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQW-FKNDMVLTESKRIKISVDEDG 3619 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQV 737 S+L+ F G Y VVA N+ G+ A IV+ + P++ Sbjct: 3620 R---SILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEI 3667 Score = 47.2 bits (107), Expect = 0.005 Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 2/137 (1%) Query: 471 AQYLMDENNYTQYLQKKLNEKIDKLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQF 529 + Y +E+ + L+ +L ++D+ + ++ + P F EK + + Sbjct: 3525 SMYAANESYSIRRLRTELGPRLDEYTEADAMIETQREGYPPFFREKPQTIAITENQPSHI 3584 Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 C G P+P + WF+ ++ S+ ++ D+D + L D G + VA+N Sbjct: 3585 HCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKV 3644 Query: 590 GFASSTTELIVEAPLSD 606 G + ++V A L D Sbjct: 3645 GQTVARCRIVV-ATLPD 3660 Score = 46.8 bits (106), Expect = 0.007 Identities = 23/98 (23%), Positives = 44/98 (44%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 T+ PP F + Q I + E + +P P + W++N+ +++ S+ I + D Sbjct: 3558 TQREGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDE 3617 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + ++ D G YK VA N G++ R+ + Sbjct: 3618 DGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVV 3655 Score = 46.0 bits (104), Expect = 0.011 Identities = 27/115 (23%), Positives = 61/115 (53%), Gaps = 11/115 (9%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 +++ ARN++G ++ +I + T P P + +S ++ + L+W +P +G S Sbjct: 3636 YKVVARNKVGQTVARC---RIVVA---TLPDAPDSPEISANSGTEILLRWKQPRDDGHST 3689 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSV-HE-HCIENIKEKDEIIFRISAENTVGVS 1949 + Y +++K +WT TV ++ HE + + +++ FR++++N +G S Sbjct: 3690 VLCYSLQYKLSNCDAWT---TVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGWS 3741 Score = 44.0 bits (99), Expect = 0.046 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 2/107 (1%) Query: 499 EKPTSEEQSMAPIFVEKLRP-KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 E+P + + AP F+ + + + + V GYP+P++T++ +I+ F Sbjct: 2872 ERPPHDGLAQAPQFLLREQDISYGVKDHNTELMWFVYGYPKPKMTYYFDDMLIESGGRFD 2931 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 Y + ATL I ++ D G + VA N G A L I E P Sbjct: 2932 QSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEIAEHP 2978 Score = 43.6 bits (98), Expect = 0.061 Identities = 28/105 (26%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Query: 494 KLPVFEKPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR-QTAII 550 +L V + P +E + P F+ L+ + + +F ++ G P+P++ +++ + I+ Sbjct: 1016 QLAVGQAPGHDETKTNTEPAFLVSLKDAEMIENTLFRFMVKIIGDPKPRVKFYKDEKEIL 1075 Query: 551 KPSQDFQMYYDDDNVA--TLVIREVFPEDAGTFTCVAKNAAGFAS 593 + + Q+ D D + LVI +V DAGT++C A N G A+ Sbjct: 1076 ETNDRIQIIRDKDYLGFYELVIADVQKTDAGTYSCKATNKHGEAN 1120 Score = 42.7 bits (96), Expect = 0.11 Identities = 31/120 (25%), Positives = 50/120 (41%), Gaps = 3/120 (2%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787 E PP E +++ + + + + VG+P+P + W KN+ + K + D D Sbjct: 3561 EGYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQWFKNDMVLTESKRIKISVDEDGR 3620 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 SI +P D GVY + A N G I V + P + N EI ++ K Sbjct: 3621 SILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWK 3680 Score = 41.1 bits (92), Expect = 0.33 Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 5/120 (4%) Query: 822 VEEPTEEN-AEPPLFINRFQEIT--VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 +E P + A+ P F+ R Q+I+ VK+ T +L+ V P P +T+Y ++ +I Sbjct: 2871 IERPPHDGLAQAPQFLLREQDISYGVKDHNT-ELMWFVYGYPKPKMTYYFDDMLIESGGR 2929 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 Q++ + N + D G Y+ VA+N G++ R+ I E F+K +++ Sbjct: 2930 FDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEARQRVRLEI-AEHPRFLKRPDETF 2988 Score = 40.7 bits (91), Expect = 0.43 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F K+P ++ + +E +LV IP P++ W + IV I ++ D +Y Sbjct: 2978 PRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIVDSSRIKIS-SYDPDIY-- 3034 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 VL I + G Y++ A N G S + + I+ E + Sbjct: 3035 VLSIHDSIIKDGGLYSISARNIAGSISTSVTVHIEENEDQ 3074 Score = 39.9 bits (89), Expect = 0.75 Identities = 44/175 (25%), Positives = 77/175 (44%), Gaps = 16/175 (9%) Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814 V G P+P +T+ ++ +++ T + T+ K + +D G Y A N G A Sbjct: 2907 VYGYPKPKMTYYFDDMLIESGGRFDQSYTRNGQATLFINKMLDRDVGWYEAVATNEHGEA 2966 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN-NEII 873 + + AE P F+ R E + + ++ A++ P+P + W+++ I+ Sbjct: 2967 RQRVRLEI-------AEHPRFLKRPDETFIMARKNGRIEAKLVGIPLPEVHWFKDWKPIV 3019 Query: 874 SPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEK 927 S ++D + L I DS I D G Y A N AG S VT+ +E+ Sbjct: 3020 DSSRIKISSYDPDIYVLSIH--DSIIKDGGLYSISARNIAGSIS--TSVTVHIEE 3070 Score = 39.9 bits (89), Expect = 0.75 Identities = 19/74 (25%), Positives = 38/74 (51%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + E ++ G P P++ WF+ I S ++ D ++ L I + +D G ++ A+N Sbjct: 2996 RIEAKLVGIPLPEVHWFKDWKPIVDSSRIKISSYDPDIYVLSIHDSIIKDGGLYSISARN 3055 Query: 588 AAGFASSTTELIVE 601 AG S++ + +E Sbjct: 3056 IAGSISTSVTVHIE 3069 >UniRef50_Q4RJ20 Cluster: Chromosome 1 SCAF15039, whole genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome 1 SCAF15039, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 3493 Score = 192 bits (469), Expect = 7e-47 Identities = 251/1203 (20%), Positives = 444/1203 (36%), Gaps = 105/1203 (8%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 +T G EC+ P P I+W++ ++ S + ++ + L I+ D G Sbjct: 998 NTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQ---MLEIKTTGVSDTG 1054 Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 + C A N AG L V + ++V +PP + Sbjct: 1055 QYVCKATNIAGQVDKNFHLNVYG-----RARLSVFTHESSCICATMPSQFSAVPPRI-EG 1108 Query: 640 PKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEI----------------------V 675 P + + E G+ + C IP P +AWL G I Sbjct: 1109 PAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPIGGAAFPSFSRLEMEKCVPLAFTC 1168 Query: 676 PDENISVAIES-DMHMYC--SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 P E S ES +MH++ L+I + GTYT VA N EG A L I+ Sbjct: 1169 PCELFSENSESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIRV--- 1225 Query: 733 EPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTH 787 PP++ E + M V ES+ L Q G P PTI W K+ + V + + D Sbjct: 1226 -PPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGT 1284 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 ++T+ D G Y A N+ G + + V P N + +E T Sbjct: 1285 TLTVF-GAHATDGGTYACVATNAAGEEDRIFNLNVYAPPVINGDS----ETVEERTAVLD 1339 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 ++ L T +P P + W RN + S + G+ + + + V DSG Y C+ Sbjct: 1340 ASVSLECVATGSPPPQLNWLRNGLPLPLSSHVRLLSAGQVLRITRSQVS---DSGAYSCI 1396 Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKK 965 ASN AG S + + V + G V L C + T + W Sbjct: 1397 ASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGS 1456 Query: 966 EISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKL 1023 + + + + G C+ K+ + S +K P I Sbjct: 1457 ALFPASNLRFL--NLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRING- 1513 Query: 1024 QDFEVKEKDVAILEVEINSETADV-----VWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 D + + ++E+ E + V W +DG +P + + G + L + + Sbjct: 1514 SDVVTEVSVIVNNDLELQCEASGVPAPSLTWLKDG---RPLADGLRVLQGGEV--LRVAS 1568 Query: 1079 TSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 + D G YSC+ + + + V +PP I + + Q V+ +E K DA Sbjct: 1569 AQLEDTGRYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLE-CKSDA 1627 Query: 1136 L----VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAIL 1189 + + W KDG +Q S +++ G L+I +LDD +Y+CE N + T Sbjct: 1628 VPPPTLTWLKDGRPLQASARVRILSRG--SYLQINQAELDDRAQYTCEASNIAGQTTRHF 1685 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIE-DTEKFTLISD 1247 V + + P N A L + VTW K +++ + ++ D Sbjct: 1686 NVAVHVAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAED 1745 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVT 1306 +L I D Y C+ + + +V++ V PP I + + ++ Sbjct: 1746 ---GSLHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTA 1802 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 L + P+P W+ N ++I ++ S SL + D +Y+ + N Sbjct: 1803 LSCEASGIPRPTVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEA 1862 Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426 G A +N+T+ P +P + + S + T+ + + Sbjct: 1863 GVASRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEER 1922 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 S+ + I + + + + R+ A N A+ +T ++ ++ T + P + Sbjct: 1923 GYSI--LPSGPLEITSAELSHTGRYTCTAEN------AAGST--HRHVQLTVQEVPVIAS 1972 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXX 1544 + + L C G P+P ++W ++G + T ++ Sbjct: 1973 QPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMSISTTGGSFTVLPNGSLRISTTSVSD 2032 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C+A N G + +Q PV I ++ + + ++G PPP V Sbjct: 2033 SGTYMCVAQNPAGTALGKIKLKVQVPPV--IGSDTRTYRAPTDSSVTLQCHVDGSPPPSV 2090 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W K+G L + + + +++ ++ + +YT A+N AGT S+E++L V Sbjct: 2091 TWNKDGQPLAESVRRRVLS---SGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQV 2147 Query: 1665 KPS 1667 PS Sbjct: 2148 PPS 2150 Score = 164 bits (399), Expect = 2e-38 Identities = 222/1051 (21%), Positives = 406/1051 (38%), Gaps = 80/1051 (7%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G+ + L C P P ++WL +G + P N+ + +M M + N G Sbjct: 1432 GNMVSLLCVADGTPTPTVSWLKEGSALFPASNLRF-LNLNMSMQIPQAHVNNT-----GR 1485 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGESVILSAQVVGNPRPT 765 Y+ VA N G+AS LK+ +PP++ + + + V + L + G P P+ Sbjct: 1486 YSCVAKNTAGQASRHFNLKV----LDPPRINGSDVVTEVSVIVNNDLELQCEASGVPAPS 1541 Query: 766 ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +TW K+ +P+ L G+ + + +++D G Y+ A + G + ++ V Sbjct: 1542 LTWLKDGRPLADGLRVLQGGE---VLRVASAQLEDTGRYSCLANSPAGDDDKEFLVRVHV 1598 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P + + Q+++V + L + P P++TW ++ + S + Sbjct: 1599 PPNIAGK-----SETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVRILSR 1653 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 G +++ +D D Y C ASN AG+++ V + V ++ ++ K Sbjct: 1654 GSYLQINQAELD---DRAQYTCEASNIAGQTTRHFNVAVHV--APSIEEGSQAVSAPVNK 1708 Query: 945 TVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 + +LEC + W + ++G + R E D G C+ Sbjct: 1709 SAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAE--DGSLHITSAQVSDTGRYLCMAT 1766 Query: 1003 DQE--TSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP 1058 +Q + ++ +P I + + D +V L E + V W ++G +I Sbjct: 1767 NQAGIQRRRVDLQVYVPPSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINT 1826 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQN 1115 +N+ + + L + +V D Y C++ +E+ A + V +PP I Sbjct: 1827 DQNQ-NMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTVHVPPFIADEPTE 1885 Query: 1116 QKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 V + + + + V+W KDG + N + L+I +L G Sbjct: 1886 MVVTRLSPVVMGCSASGVPEPTVQWSKDG--VALPNEERGYSILPSGPLEITSAELSHTG 1943 Query: 1175 EYSC----EVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 Y+C G++ LTV+E P I + IL T P T ++W Sbjct: 1944 RYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTLPCRATGSPRPT--ISW 2001 Query: 1230 YKKKSVIEDT-EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287 K+ I T FT++ + +L I + D Y CV + T K+++ V+ P Sbjct: 2002 QKEGMSISTTGGSFTVLPN---GSLRISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVP 2058 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P I R YR S VTL P P+ W + + + + + S SL + Sbjct: 2059 PVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRV---LSSGSLQL 2115 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSIN-ICWDEPE 1405 V++ D G Y N G +EM++T+ PS G+ + +++S + +C E Sbjct: 2116 AFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVC--VAE 2173 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 T+ + +++E +V + + I + + R+ A NE+ + Sbjct: 2174 GVPQPTLSWEKDGNLFSESSEEPTV--LPSGELIITRAQAEDAGRYTCVATNELGQDRWT 2231 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 T P + L ++ + E + L C G+P P +TW + L Sbjct: 2232 ATLSVQ--------THPVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILPVH 2283 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-- 1583 Y C+A N G +++ V I + P+I + D++ Sbjct: 2284 YDHANGHSQLVIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPII---DGDLRSNRI 2340 Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSK 1642 +G ++ + G PPP + W KNG + D+ + + E + Sbjct: 2341 EPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQLNNGSLAIYGTVSE----DAGS 2396 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 YT A+N AG VTL + P+ E PV Sbjct: 2397 YTCVATNDAGAVERSVTLTLQRAPTITEEPV 2427 Score = 158 bits (383), Expect = 2e-36 Identities = 240/1171 (20%), Positives = 407/1171 (34%), Gaps = 77/1171 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V F C G P P + W + I + F + + + + P + + Sbjct: 1119 GNPVSFACDATGIPPPALAWLKNGRPIGGAA-FPSFSRLEMEKCVPLAFTCPCELFSENS 1177 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS--KKPK 641 + F+ I + +SD G+ V + +PP S + P+ Sbjct: 1178 ESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIR-VPPRISGSELPR 1236 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 V I L C+ P P I WL GE + + + I D + L + Sbjct: 1237 EMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPD----GTTLTVFGAH 1292 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQV 758 GTY VA N GE L + PP + E ++ SV L Sbjct: 1293 ATDGGTYACVATNAAGEEDRIFNLNVYA----PPVINGDSETVEERTAVLDASVSLECVA 1348 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 G+P P + W +N P+ + + +V D G Y+ A N G+ Sbjct: 1349 TGSPPPQLNWLRNGLPLPLSSHVRLLSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHY 1408 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V P + +++TV + L+ P P+++W + + P+ Sbjct: 1409 NLQVHVPPGLDG-----AGSTEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASN 1463 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS-HGARVTIDVEKVTFVKHLQKS 937 + F N+ + I ++G Y CVA N+AG++S H +D ++ + Sbjct: 1464 L--RFLNLNMSMQIPQAHVN-NTGRYSCVAKNTAGQASRHFNLKVLDPPRIN-GSDVVTE 1519 Query: 938 YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + L+C+ S S W + + ++ D ++Q G D G Sbjct: 1520 VSVIVNNDLELQCEASGVPAPSLTWLKDGRPLA--DGLRVLQGGE--VLRVASAQLEDTG 1575 Query: 996 VIKCIVKDQ--ETSTMLVVKETIPEFI---RKLQDFEVKEKDVAILEVEINS-ETADVVW 1049 C+ + +V+ +P I + QD V LE + ++ + W Sbjct: 1576 RYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTW 1635 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-VELP 1106 +DG ++ + RG L I + D +Y+C + T V V + Sbjct: 1636 LKDGRPLQASA-RVRILSRGSY--LQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVA 1692 Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLK 1164 P I Q A E + V W K G+ + +N + DG L Sbjct: 1693 PSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAEDG---SLH 1749 Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE- 1219 I + D G Y C + G + L V P RL + V N L+ E Sbjct: 1750 ITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPSISEGRLD--VKVTVNVQTALSCEA 1807 Query: 1220 --IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 IP T VTW K VI + + + +L++ T +D Y CV+ + Sbjct: 1808 SGIPRPT--VTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVA 1865 Query: 1278 KLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 + + V PP I D E + R S V + P+P +W + + + Sbjct: 1866 SRFINLTVHVPPFIADEPTEMVVTRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYS 1925 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 + S +T ++ +T G Y EN G + +T+ + P +P+ L++ + Sbjct: 1926 ILPSGPLEITSAELSHT--GRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKN 1983 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 + TI + E I TT S + I + S + A Sbjct: 1984 PVTLPCRATGSPRPTISWQ-KEGMSISTTGG-SFTVLPNGSLRISTTSVSDSGTYMCVAQ 2041 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N T K+ + ++ P + + + + L C G P P VTW Sbjct: 2042 NPAG-------TALGKIKLKVQV-PPVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWN 2093 Query: 1517 RDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 +DG+ L ++ + + Y C A N G V + +Q P I Sbjct: 2094 KDGQPLAESVRRRVLSSGSLQLAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRG 2153 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 +++ + V EG+P P + W K+GN E T + + I Sbjct: 2154 GEKEVAVVE--NSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEE--PTVLPSGELIITRA 2209 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + +YT A+N G TL V P Sbjct: 2210 QAEDAGRYTCVATNELGQDRWTATLSVQTHP 2240 Score = 134 bits (323), Expect = 3e-29 Identities = 216/1059 (20%), Positives = 384/1059 (36%), Gaps = 114/1059 (10%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 ++ +C+ G P P +TW + +P D V + ++ ED G ++C+A Sbjct: 1528 LELQCEASGVPAPSLTWLKDG---RPLADGLRVLQGGEVLRVASAQL--EDTGRYSCLAN 1582 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646 +P D E V +PP + K + Q V Sbjct: 1583 ---------------SPAGDDDKEFLVRVH---------------VPPNIAGKSETQDVS 1612 Query: 647 E--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + LEC+ A+P P + WL G + + + S L+I + Sbjct: 1613 VLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVRILSRG------SYLQINQAELDD 1666 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 YT A N G+ + + + P + E +++ +S +L V G P P Sbjct: 1667 RAQYTCEASNIAGQTTRHFNVAVHVA----PSIEEGSQAVSAPVNKSAVLECVVNGVPPP 1722 Query: 765 TITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 +TW K+ + + DG H + +V D G Y A N GI + Sbjct: 1723 QVTWRKHGAILAGNNPRYRFAEDGSLH----ITSAQVSDTGRYLCMATNQAGIQRRRVDL 1778 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 V P P + R ++ V L + P P++TW +N +I+ + Sbjct: 1779 QVYVP------PSISEGRL-DVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQN 1831 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + LV+ E D+ Y+CV SN AG +S +T+ V F+ Sbjct: 1832 MYRLLTSGSLVVIAPTVE-DTAVYECVVSNEAGVASRFINLTVHVP--PFIADEPTEMVV 1888 Query: 941 EEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 V++ C S +K ++ + G C Sbjct: 1889 TRLSPVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPLEITSAELSHTGRYTCT 1948 Query: 1001 VKDQETST----MLVVKETIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGEI 1055 ++ ST L V+E +P + +V K+ L S + W+++G Sbjct: 1949 AENAAGSTHRHVQLTVQE-VPVIASQPSTLDVILKNPVTLPCRATGSPRPTISWQKEGMS 2007 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITR 1112 I + G +R I TSV D G Y C+ ++ + TA + V++PP I + Sbjct: 2008 ISTTGGSFTVLPNGSLR---ISTTSVSDSGTYMCVAQNPAGTALGKIKLKVQVPPVIGSD 2064 Query: 1113 LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 + + + T + + V W KDG + S ++ G L++ + Sbjct: 2065 TRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRVLSSG---SLQLAFVQSE 2121 Query: 1172 DAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPE-FILVPANTDAYLTV---EIPDETLD 1226 D G Y+C N T L + + ++R E + V N+ L +P TL Sbjct: 2122 DTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEVAVVENSRVQLVCVAEGVPQPTL- 2180 Query: 1227 VTWYKKKSVI-EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 +W K ++ E +E+ T++ + LII + +D YTCV + + + V Sbjct: 2181 -SWEKDGNLFSESSEEPTVLPSGE---LIITRAQAEDAGRYTCVATNELGQDRWTATLSV 2236 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P + + +K+G + L P P+ W+ N+ I+ H + + + Sbjct: 2237 QTHPVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILP--VHYDHA--NGHSQ 2292 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG--KPNILE-IDSSSINICW 1401 L I++V D+G Y EN G V+IL+ P G + N +E + +++ C Sbjct: 2293 LVIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPIIDGDLRSNRIEPLGGNAVLNC- 2351 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 E TI + I T ++ + +I + + + A N+ Sbjct: 2352 -EVRGDPPPTIRW---SKNGIHITIGDRIRQLNNGSLAIYGTVSEDAGSYTCVATNDAGA 2407 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + S T T ++PT+ + + + L C G P P + W + G+ Sbjct: 2408 VERSVTL--------TLQRAPTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRP 2459 Query: 1522 -LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 L + + + Y+C+A N G V Sbjct: 2460 LLGNDRFSSLSNGSLRISSVQKEDTARYECVARNLVGSV 2498 Score = 132 bits (318), Expect = 1e-28 Identities = 243/1178 (20%), Positives = 419/1178 (35%), Gaps = 139/1178 (11%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 ++ A +SD G + V + P P++ V S + L C Sbjct: 858 VLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVVVNSFVSLSCEAT 917 Query: 659 AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE 718 +P P + WL + + + + L+I K G Y+ VA+N GE Sbjct: 918 GLPPPTLTWLNDRGPVQANTHALIMPGG------RTLQIMKAKVSDGGKYSCVAMNAAGE 971 Query: 719 ASLPIVL------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 A I L I+ + P V+ L G++ L + P P+I+W KN Sbjct: 972 AHRHIYLTVFIPPSIRGSSGDSPVVVNTLA------GKASTLECETSAVPAPSISWYKNG 1025 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG------------------IA 814 + V + +K V D G Y KA N G Sbjct: 1026 RVVTESANLRILKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNVYGRARLSVFT 1085 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEII 873 S+ I P++ +A PP +E + G + T P P++ W +N I Sbjct: 1086 HESSCICATMPSQFSAVPPRIEGPAEEDIAETLGNPVSFACDATGIPPPALAWLKNGRPI 1145 Query: 874 S----------------------PSETITQNFDGENIELVITNVDSEI--------DSGD 903 P E ++N E++E+ I + ++ DSG Sbjct: 1146 GGAAFPSFSRLEMEKCVPLAFTCPCELFSEN--SESLEMHIFSGGGKLQIARSQVSDSGT 1203 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST--KWY 961 Y CVASN G++ R+TI V L + +++ L CQ S T + +W Sbjct: 1204 YTCVASNVEGRAHKSYRLTIRVPPRISGSELPREMGVLLNESIQLVCQASGTPTPTIQWL 1263 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEF 1019 + + ++ E+ D G C+ + E + + P Sbjct: 1264 KDGEAVNHTGSSELRISPDGTTLTVFGAHATDGGTYACVATNAAGEEDRIFNLNVYAPPV 1323 Query: 1020 IRKLQDFEVKEKDVAILEVEINSETA-------DVVWERDGEIIKPKKNKYDFEKRGHIR 1072 I D E E+ A+L+ ++ E + W R+G + P + G + Sbjct: 1324 ING--DSETVEERTAVLDASVSLECVATGSPPPQLNWLRNG-LPLPLSSHVRLLSAGQV- 1379 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNK-GNKATFEI 1128 L I + V D G YSCI + + V +PP + + V G + Sbjct: 1380 -LRITRSQVSDSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAGSTEDVTVVGGNMVSLL 1438 Query: 1129 ELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 + G V W K+GS + +++++ ++I +++ G YSC N+ Sbjct: 1439 CVADGTPTPTVSWLKEGSALFPASNLRFL--NLNMSMQIPQAHVNNTGRYSCVAKNTAGQ 1496 Query: 1187 A-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIED 1238 A + ++ P IN + + E + V N D L E +P +L TW K + D Sbjct: 1497 ASRHFNLKVLDPPRINGSDVVTE-VSVIVNNDLELQCEASGVPAPSL--TWLKDGRPLAD 1553 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYE--R 1295 + +V L + +D Y+C+ A K + V PP I + Sbjct: 1554 GLRVLQGGEV----LRVASAQLEDTGRYSCLANSPAGDDDKEFLVRVHVPPNIAGKSETQ 1609 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + + VTL A P P W+ + + ++ + I S+ + L I + E D Sbjct: 1610 DVSVLLNRPVTLECKSDAVPPPTLTWLKDGRPLQASARVR--ILSRGSYLQINQAELDDR 1667 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 Y N G NV + PS +E S +++ P N S ++ Sbjct: 1668 AQYTCEASNIAGQTTRHFNVAVHVAPS-------IEEGSQAVSA----PVN--KSAVLEC 1714 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 VV W I + S + V++ T + + Sbjct: 1715 VVNGVPPPQVTWRKHGAILAGNNPRYRFAEDGSLHITSAQVSDTGRYLCMATNQAGIQRR 1774 Query: 1476 ETKIQ---SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 +Q P++ + ++ N L+C G+P+P VTW ++G+ + T + R Sbjct: 1775 RVDLQVYVPPSISEGRLDVKVTVNVQTALSCEASGIPRPTVTWMKNGRVINTDQNQNMYR 1834 Query: 1533 XXXXXXXXXXX----XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD 1588 Y+C+ N+ G + + P I ++E + Sbjct: 1835 LLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTVHVPPFI--ADEPTEMVVTRLS 1892 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 ++ G+P P V W K+G L N++ Y+I + + I + SH+ +YT A Sbjct: 1893 PVVMGCSASGVPEPTVQWSKDGVALPNEERGYSILP---SGPLEITSAELSHTGRYTCTA 1949 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 N AG++ V L V + P P + I + VT+ Sbjct: 1950 ENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTL 1987 Score = 115 bits (277), Expect = 1e-23 Identities = 200/933 (21%), Positives = 349/933 (37%), Gaps = 92/933 (9%) Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVA 854 +V D G YT A N EG A S +T+ P +E P +E+ V +I+LV Sbjct: 1197 QVSDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSELP------REMGVLLNESIQLVC 1250 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 + + P P+I W ++ E ++ + + + L + + D G Y CVA+N+AG+ Sbjct: 1251 QASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHAT-DGGTYACVATNAAGE 1309 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVST-------KWYHNKKE 966 + + V + ET E +T +L+ S V+T W N Sbjct: 1310 EDRIFNLNVYAPPV-----INGDSETVEERTAVLDASVSLECVATGSPPPQLNWLRNGLP 1364 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE--TSTMLVVKETIPEFIRKLQ 1024 + H ++ G+ D G CI ++ S ++ +P + Sbjct: 1365 LPLSSHVRLLSAGQVLRITRSQVS--DSGAYSCIASNRAGVDSRHYNLQVHVPPGLDGAG 1422 Query: 1025 DFE----VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 E V V++L V + T V W ++G + P N + I Sbjct: 1423 STEDVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASNLRFLNLN---MSMQIPQAH 1479 Query: 1081 VHDEGEYSCILRDESCTAE----VTVVELP----PEIITRLQNQKVNKGNKATFEIELTK 1132 V++ G YSC+ ++ + A + V++ P +++T + + VN + E Sbjct: 1480 VNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDVVTEV-SVIVNNDLELQCEASGVP 1538 Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAI 1188 +L W KDG + ++ +++ G + L++ L+D G YSC G+ + Sbjct: 1539 APSLT-WLKDGRPL--ADGLRVLQGG--EVLRVASAQLEDTGRYSCLANSPAGDDDKEFL 1593 Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLI 1245 + V P + + V N L + +P TL TW K ++ + + ++ Sbjct: 1594 VRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTL--TWLKDGRPLQASARVRIL 1651 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304 S + L I + DD+ +YTC + A TT+ V P I + + Sbjct: 1652 S--RGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVAPSIEEGSQAVSAPVNKS 1709 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 L P P W + I+ + ++ SL I + +D G Y N Sbjct: 1710 AVLECVVNGVPPPQVTWRKHGAIL--AGNNPRYRFAEDGSLHITSAQVSDTGRYLCMATN 1767 Query: 1365 NCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 G +++ + PS G+ ++ ++N+ T + Sbjct: 1768 QAGIQRRRVDLQVYVPPSISEGRLDV----KVTVNV----------QTALSCEASGIPRP 1813 Query: 1424 TTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISD---ASETTEYYKVIKETK 1478 T W+ + T + + L T+ S A V + + + ++E + I T Sbjct: 1814 TVTWMKNGRVINTDQNQNMYRLLTSGSLVVIAPTVEDTAVYECVVSNEAGVASRFINLTV 1873 Query: 1479 IQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXX 1535 P + ++P + + T + + + C GVP+P V W +DG L + Y Sbjct: 1874 HVPPFIADEPTEMVVTRLSP-VVMGCSASGVPEPTVQWSKDGVALPNEERGYSILPSGPL 1932 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKHKVGDEWLVT 1593 Y C A N G + +Q+ PVI S D+ K+ V T Sbjct: 1933 EITSAELSHTGRYTCTAENAAGSTHRHVQLTVQEVPVIASQPSTLDVILKNPVTLPCRAT 1992 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 G P P + W K G + + T S +RI S S Y A N AGT Sbjct: 1993 ----GSPRPTISWQKEGMSISTTGG-SFTVLPNGS-LRISTTSVSDSGTYMCVAQNPAGT 2046 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + ++ LKV P R + SVT++ Sbjct: 2047 ALGKIKLKVQVPPVIGSDTRTYRAPTDSSVTLQ 2079 Score = 105 bits (251), Expect = 2e-20 Identities = 102/469 (21%), Positives = 197/469 (42%), Gaps = 37/469 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP + + V G V+L Q P PT++W K+ +P+ P + S+ + Sbjct: 2 PPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSVLRVD 61 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKL 852 +V+D G Y+ +A N G E + + V P+ +E P +TV E I + Sbjct: 62 SAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEP------TPLTVIEGNPITM 115 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 V + P PS+ W ++ + P++ + G +++ + + D+ Y C AS+++ Sbjct: 116 VCESSGIPPPSLVWRKDGSELKPTQRLRVLSGGRQLQI---SSAARTDTASYSCTASSAS 172 Query: 913 GKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISG 969 G +S + + V + + L +G V L+C + W + + +SG Sbjct: 173 GITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSG 232 Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV------KDQETSTMLVVKETIPEFIRKL 1023 +++ EGR D G C+ D + V I + Sbjct: 233 QHRAKVLNEGR--LLQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVP 290 Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 ++ V K+ L E + + W +DG+ ++ + + R L + + +V Sbjct: 291 ENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGG---RSLRLMHAAVG 347 Query: 1083 DEGEYSCILR----DESCTAEVTVVELPPEIITR--LQNQKVNKGNKATFEIELTKGDAL 1136 D G Y+C++ +E ++ ++ +PP I + + KV + + T E++ G+ + Sbjct: 348 DGGRYTCVVSNMAGEERKNFDLDIL-VPPSIEEEGTVVDTKVKEKHNLTLTCEVS-GNPV 405 Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++W KDG + H Q+ +G+ L+I+ + D G YSC NS Sbjct: 406 PGIKWLKDGQMLVSDRHHQVFSNGR--FLQIFGTRVADTGRYSCLASNS 452 Score = 104 bits (250), Expect = 2e-20 Identities = 117/555 (21%), Positives = 207/555 (37%), Gaps = 35/555 (6%) Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPE 1204 S +++ I KL+I + D+G Y+C N + A LT+ P LP Sbjct: 1177 SESLEMHIFSGGGKLQIARSQVSDSGTYTCVASNVEGRAHKSYRLTIRVPPRISGSELPR 1236 Query: 1205 FILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + V N L + T + W K + T L TL + D Sbjct: 1237 EMGVLLNESIQLVCQASGTPTPTIQWLKDGEAVNHTGSSELRISPDGTTLTVFGAHATDG 1296 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF----PQPND 1319 Y CV +A + + P +++ + E +R + + V + P P Sbjct: 1297 GTYACVATNAAGEEDRIFNLNVYAPPVINGDSETVEERTAVLDASVSLECVATGSPPPQL 1356 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 W+ N + H + + S L I + + +D+G Y N G N+ + Sbjct: 1357 NWLRNGLPLPLSSHVR--LLSAGQVLRITRSQVSDSGAYSCIASNRAGVDSRHYNLQV-- 1412 Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 PPG +D + D GN + V + T W+ + ++ Sbjct: 1413 -HVPPG------LDGAGSTE--DVTVVGGNMVSLLCVADGTPTPTVSWLKEGSALFPASN 1463 Query: 1440 IQNLKTNSSYRFRAYAVNE------VDISDASETTEYY--KVIKETKIQSPTVEKPLKNI 1491 ++ L N S + VN V + A + + ++ KV+ +I V + + Sbjct: 1464 LRFLNLNMSMQIPQAHVNNTGRYSCVAKNTAGQASRHFNLKVLDPPRINGSDV---VTEV 1520 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 + N D+EL C GVP P +TW +DG+ L + Y C+ Sbjct: 1521 SVIVNNDLELQCEASGVPAPSLTWLKDGRPLADGLRVLQGGEVLRVASAQLEDTGRYSCL 1580 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 A + G+ + +V + P I +E + + + +PPP + W K+G Sbjct: 1581 ANSPAGDDDKEFLVRVHVPPNIAGKSETQDVSVLLNRPVTLECKSDAVPPPTLTWLKDGR 1640 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 L+ I + + S ++I + + ++YT EASN AG ++ + V+ PS EG Sbjct: 1641 PLQASARVRILS--RGSYLQINQAELDDRAQYTCEASNIAGQTTRHFNVAVHVAPSIEEG 1698 Query: 1672 PVIMREISRESVTIE 1686 + +S +E Sbjct: 1699 SQAVSAPVNKSAVLE 1713 Score = 102 bits (245), Expect = 9e-20 Identities = 102/473 (21%), Positives = 179/473 (37%), Gaps = 41/473 (8%) Query: 514 EKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 E L+PK S++ EC + +P P + W++ I++ + V + Sbjct: 604 EGLKPKEVKVKVNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRMVQ---VE 660 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 D G +TCVA N AG ++ V+ P + + D++ Sbjct: 661 HARVSDTGRYTCVATNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILN 720 Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 P I L C A+P P + W G+ + + + + Sbjct: 721 NP-----------------ISLYCETNAVPPPTLTWYKDGQLLASGDKVLILPGG----- 758 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 VL+I + G Y +AVN GE S+ +++ V + + + V ++ Sbjct: 759 -RVLQIPRAQAEDAGRYICMAVNEAGEDSIHYDVRVLLPPIIRGTVSDFPEEVTVLVNKT 817 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L GNP P ++W ++++PV+ I + +V D G Y A N Sbjct: 818 TQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGRILQVLTAQVSDTGRYVCVAANVA 877 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G AE S + V P P + + + + V + L T P P++TW + Sbjct: 878 GSAEKSFNLNVHVP------PMVIGSNPESVNVVVNSFVSLSCEATGLPPPTLTWLNDRG 931 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + + G ++++ V D G Y CVA N+AG++ +T+ + Sbjct: 932 PVQANTHALIMPGGRTLQIMKAKVS---DGGKYSCVAMNAAGEAHRHIYLTVFIPPSIRG 988 Query: 932 KHLQKS--YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980 T GK LEC+TS S WY N + ++ + I++EG+ Sbjct: 989 SSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEGQ 1041 Score = 101 bits (243), Expect = 2e-19 Identities = 88/337 (26%), Positives = 134/337 (39%), Gaps = 20/337 (5%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V +G D+ L+C IP P + WL G + V E + L+I VK Sbjct: 201 VTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGRL------LQIKTVKVSD 254 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G YT VAVN G+A + + QV P +V + V LS + G P P Sbjct: 255 TGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENVSVVLKNP-VALSCEASGIPLP 313 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 I+W K+ +PV+A + L V D G YT N G + + + Sbjct: 314 AISWLKDGQPVRASSSVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILV 373 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P E + + VKEK + L V+ NPVP I W ++ +++ + Sbjct: 374 PPSIEEEGTVV-----DTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSN 428 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE----T 940 G +++ T V D+G Y C+ASNSAG+ S + + V + S E T Sbjct: 429 GRFLQIFGTRV---ADTGRYSCLASNSAGERSRHYNLNVLVSPTIAGSGPEGSVEEVTVT 485 Query: 941 EEGKTVIL-ECQTSHTVSTKWYHNKKEISGMDHREII 976 T +L + Q+ W + DH ++ Sbjct: 486 ASSPTSLLCDAQSYPPAVVTWLRDGSSFESSDHVRVL 522 Score = 101 bits (241), Expect = 3e-19 Identities = 158/741 (21%), Positives = 271/741 (36%), Gaps = 60/741 (8%) Query: 476 DENNYTQYLQKKLNE--KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 D YT + E K L + P+ EE+ + K++ KH + C+V Sbjct: 348 DGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGT--VVDTKVKEKHN-----LTLTCEV 400 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P P I W + ++ + Q++ N L I D G ++C+A N+AG S Sbjct: 401 SGNPVPGIKWLKDGQMLVSDRHHQVF---SNGRFLQIFGTRVADTGRYSCLASNSAGERS 457 Query: 594 S--TTELIVEAPLSDHGSEMTVXXXXXXXXX-XXXADILEGIPPTFSKKPKAQYVDEGSD 650 ++V ++ G E +V + PP ++ +GS Sbjct: 458 RHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSYPPAV-----VTWLRDGSS 512 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISV-AIESDMHMYCSVLKITNVKKFQEGTYT 709 + +P + K E + + L+I N K+ G YT Sbjct: 513 FESSDHVRVLPGVTLGMTVKMSEGIRSLAYGCHGFITPASAGGRTLQILNAKEEDAGRYT 572 Query: 710 VVAVNREGEASLPIVLKI-----KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 VA N GE LK+ P + ++P K + V+ S+ L P P Sbjct: 573 CVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKP-KEVKVKVNSSLTLECAAQAFPSP 631 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 + W K+ + ++ S + + ++ +V D G YT A N G E + V+ Sbjct: 632 ALQWYKDGQILQVDDHMSITASGRMVQVEHARVSDTGRYTCVATNIAGEDEKDFDVNVQV 691 Query: 825 P---TEENAEPPLFINRFQEITVKE---KGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 P T + E V++ I L P P++TWY++ ++++ + Sbjct: 692 PPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAVPPPTLTWYKDGQLLASGDK 751 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVTIDVEKVTFVKHLQK 936 + G + L I +E D+G Y C+A N AG+ S + RV + V + Sbjct: 752 VL-ILPGGRV-LQIPRAQAE-DAGRYICMAVNEAGEDSIHYDVRVLLPPIIRGTVSDFPE 808 Query: 937 SYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994 KT LEC + + W+ + + + I+ GR D Sbjct: 809 EVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNGR--ILQVLTAQVSDT 866 Query: 995 GVIKCIVKDQETST--MLVVKETIPEFI--RKLQDFEVKEKDVAILEVEINS-ETADVVW 1049 G C+ + S + +P + + V L E + W Sbjct: 867 GRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVVVNSFVSLSCEATGLPPPTLTW 926 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELP 1106 D + + N + G R L I V D G+YSC+ + + A V +P Sbjct: 927 LNDRGPV--QANTHALIMPGG-RTLQIMKAKVSDGGKYSCVAMNAAGEAHRHIYLTVFIP 983 Query: 1107 PEIITRLQNQKV----NKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P I + V G +T E E + A + W+K+G + S ++++ +G Q Sbjct: 984 PSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKNGRVVTESANLRILKEG--Q 1041 Query: 1162 KLKIYDCDLDDAGEYSCEVGN 1182 L+I + D G+Y C+ N Sbjct: 1042 MLEIKTTGVSDTGQYVCKATN 1062 Score = 100 bits (239), Expect = 5e-19 Identities = 81/347 (23%), Positives = 146/347 (42%), Gaps = 18/347 (5%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S++P V EG+ I + C IP P + W G E+ P + + V L+ Sbjct: 99 SEEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSGGRQ------LQ 152 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESVILS 755 I++ + +Y+ A + G S L++ + ++ E L + V +G V L Sbjct: 153 ISSAARTDTASYSCTASSASGITSKEYSLQVYV--RPSIKLSEGLSDDVAVTKGGDVTLQ 210 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G PRP +TW K+ +PV + + +K KV D G YT A N+ G A+ Sbjct: 211 CAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQAD 270 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 + ++V P + ++ + ++V K + L + P+P+I+W ++ + + Sbjct: 271 SRHDVSVHVPPVITGQ----VDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRA 326 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 S ++ G ++ L+ V D G Y CV SN AG+ + I V + Sbjct: 327 SSSVHVLSGGRSLRLMHAAVG---DGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTV 383 Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980 + +E + L C+ S KW + + + H ++ GR Sbjct: 384 VDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSNGR 430 Score = 95.5 bits (227), Expect = 1e-17 Identities = 102/393 (25%), Positives = 158/393 (40%), Gaps = 54/393 (13%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 + C+ P P +TW++ ++ S D + V L I EDAG + C+A Sbjct: 723 ISLYCETNAVPPPTLTWYKDGQLLA-SGDKVLILPGGRV--LQIPRAQAEDAGRYICMAV 779 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646 N AG S ++ V P I+ G T S P+ V Sbjct: 780 NEAGEDSIHYDVRVLLP-----------------------PIIRG---TVSDFPEEVTVL 813 Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 LEC P P ++W + + PD + +L++ + G Sbjct: 814 VNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSNG------RILQVLTAQVSDTG 867 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPT 765 Y VA N G A L + PP VI +S+ V V LS + G P PT Sbjct: 868 RYVCVAANVAGSAEKSFNLNVHV----PPMVIGSNPESVNVVVNSFVSLSCEATGLPPPT 923 Query: 766 ITWCKNNKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +TW + PV+A ++ I+K K V D G Y+ A N+ G A +TV Sbjct: 924 LTWLNDRGPVQANTHALIMPGGRTLQIMKAK-VSDGGKYSCVAMNAAGEAHRHIYLTVFI 982 Query: 825 PTE---ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 P + + P+ +N T+ K + L + P PSI+WY+N +++ S + Sbjct: 983 PPSIRGSSGDSPVVVN-----TLAGKAST-LECETSAVPAPSISWYKNGRVVTESANLRI 1036 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 +G+ +E+ T V D+G Y C A+N AG+ Sbjct: 1037 LKEGQMLEIKTTGVS---DTGQYVCKATNIAGQ 1066 Score = 91.9 bits (218), Expect = 2e-16 Identities = 114/546 (20%), Positives = 215/546 (39%), Gaps = 48/546 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP + V G ++L C+ AIP P ++W G + ++V + Sbjct: 1 VPPNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDG----- 55 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 SVL++ + + G Y+ A N G+ L + EP ++ +G Sbjct: 56 -SVLRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSE-EPTPLTVI-EGNP 112 Query: 752 VILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + + + G P P++ W K+ KP + L S G + I + D Y+ A Sbjct: 113 ITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSGG--RQLQISSAART-DTASYSCTAS 169 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 ++ GI TS +++ + + L ++ V + G + L P P++TW + Sbjct: 170 SASGI--TSKEYSLQVYVRPSIK--LSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLK 225 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + +S +G +++ V D+G Y CVA N+AG++ V++ V V Sbjct: 226 DGRPVSGQHRAKVLNEGRLLQIKTVKVS---DTGRYTCVAVNAAGQADSRHDVSVHVPPV 282 Query: 929 -TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 T + ++ V L C+ S + W + + + ++ GR Sbjct: 283 ITGQVDVPENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGR--SLR 340 Query: 986 XXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEI 1040 D G C+V + E + +P I + + D +VKEK L E+ Sbjct: 341 LMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEV 400 Query: 1041 N-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----- 1094 + + + W +DG+++ ++ F R L I T V D G YSC+ + Sbjct: 401 SGNPVPGIKWLKDGQMLVSDRHHQVFSNG---RFLQIFGTRVADTGRYSCLASNSAGERS 457 Query: 1095 -----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQF 1148 + T+ PE ++ V + + + + A+V W +DGS + Sbjct: 458 RHYNLNVLVSPTIAGSGPE--GSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRDGSSFES 515 Query: 1149 SNHIQL 1154 S+H+++ Sbjct: 516 SDHVRV 521 Score = 91.1 bits (216), Expect = 3e-16 Identities = 101/459 (22%), Positives = 183/459 (39%), Gaps = 29/459 (6%) Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---------REYRIKR 1301 RTL I E+D YTCV + T E+ F P ++ +E ++K Sbjct: 556 RTLQILNAKEEDAGRYTCVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKPKEVKVKV 615 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 S +TL QAFP P +W + +I++ H SI + + ++ +D G Y Sbjct: 616 NSSLTLECAAQAFPSPALQWYKDGQILQVDDHM--SITASGRMVQVEHARVSDTGRYTCV 673 Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTI-IYYVVEYQ 1420 N G + + +V + P+ +SS + D + N+ I +Y Sbjct: 674 ATNIAGEDEKDFDVNVQVPPNFTRAGGAAG-STSSPGVEGDVRDVILNNPISLYCETNAV 732 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRF-RAYAVNE-----VDISDASETTEYYKV- 1473 T W + + + L + RA A + + +++A E + +Y V Sbjct: 733 PPPTLTWYKDGQLLASGDKVLILPGGRVLQIPRAQAEDAGRYICMAVNEAGEDSIHYDVR 792 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYEN 1531 + I TV + +T N+ +L C G P P+V+W++D + ++ N Sbjct: 793 VLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILSN 852 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C+A N G E S + + P++ SN + V Sbjct: 853 GRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPE-SVNVVVNSFVS 911 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 ++ G+PPP + W + ++ + I +T ++I + K S KY+ A N A Sbjct: 912 LSCEATGLPPPTLTWLNDRGPVQANTHALIMPGGRT--LQIMKAKVSDGGKYSCVAMNAA 969 Query: 1652 GTSSVEVTLKVYDKP----SKPEGPVIMREISRESVTIE 1686 G + + L V+ P S + PV++ ++ ++ T+E Sbjct: 970 GEAHRHIYLTVFIPPSIRGSSGDSPVVVNTLAGKASTLE 1008 Score = 85.0 bits (201), Expect = 2e-14 Identities = 92/331 (27%), Positives = 134/331 (40%), Gaps = 29/331 (8%) Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 ELI+ ++ T A + P F++ + +G +LL C Sbjct: 2203 ELIITRAQAEDAGRYTCVATNELGQDRWTATLSVQTHPVFTELLGDVALKKGERLLLACG 2262 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + IP P I W+F I+P + D S L I V K GTYT VA NR Sbjct: 2263 VNGIPTPHITWVF-NNSILP-------VHYDHANGHSQLVIERVTKEDSGTYTCVAENRV 2314 Query: 717 GE-ASLPIVLKIKTGEKEPPQVIEPLKS-MIVRQGESVILSAQVVGNPRPTITWCKNNKP 774 G SL V + EPP + L+S I G + +L+ +V G+P PTI W KN Sbjct: 2315 GTIKSLGFVSIL-----EPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIH 2369 Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 + + S+ I +D G YT A N G E S +T++ EP Sbjct: 2370 ITIGDRIRQLNNGSLAIYGTVS-EDAGSYTCVATNDAGAVERSVTLTLQRAPTITEEP-- 2426 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 V T+ L + P P+I W + + ++ + +G L I++ Sbjct: 2427 -----VGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNG---SLRISS 2478 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 V E D+ Y+CVA N G S ARV + V Sbjct: 2479 VQKE-DTARYECVARNLVG--SVLARVPLTV 2506 Score = 81.4 bits (192), Expect = 2e-13 Identities = 102/502 (20%), Positives = 188/502 (37%), Gaps = 35/502 (6%) Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTV-EE 1193 W KDG + + + DG L++ + D+G YSCE G ++ L V Sbjct: 36 WRKDGRPLFRKPGLTVLSDGSV--LRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVA 93 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 PSI + ++ N + + W K S ++ T++ ++S R L Sbjct: 94 PSIRGSEEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVLSG--GRQL 151 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER---EYRIKRGSDVTLLV 1309 I D Y+C A T + + V P I E + + +G DVTL Sbjct: 152 QISSAARTDTASYSCTASSASGITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQC 211 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 + P+P W+ + + + +H + + ++ L IK V+ +D G Y N G A Sbjct: 212 AAEGIPRPAVTWLKDGRPVSG-QH-RAKVLNEGRLLQIKTVKVSDTGRYTCVAVNAAGQA 269 Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 D +V++ P G+ ++ E ++++ P + + W+ Sbjct: 270 DSRHDVSVHVPPVITGQVDVPE----NVSVVLKNP------VALSCEASGIPLPAISWLK 319 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNE---VDISDASETTEYYKVIKETKIQSPTVEK 1486 + +S+ L S R AV + ++ E K + P++E+ Sbjct: 320 DGQPVRASSSVHVLSGGRSLRLMHAAVGDGGRYTCVVSNMAGEERKNFDLDILVPPSIEE 379 Query: 1487 PLKNITTEPNE--DIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXX 1542 + T+ E ++ LTC G P P + W +DG+ L + + + N Sbjct: 380 EGTVVDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRV 439 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI---EGI 1599 Y C+A N GE + + P I S + + T+++ + Sbjct: 440 ADTGRYSCLASNSAGERSRHYNLNVLVSPTIAGSGPEGSVEEVTVTASSPTSLLCDAQSY 499 Query: 1600 PPPEVIWYKNGNKLENDKEYNI 1621 PP V W ++G+ E+ + Sbjct: 500 PPAVVTWLRDGSSFESSDHVRV 521 Score = 79.8 bits (188), Expect = 8e-13 Identities = 100/510 (19%), Positives = 198/510 (38%), Gaps = 40/510 (7%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 ++ +N T+ L +++ +DA IP TL +W K + T++SD Sbjct: 5 IQGEELNATVMLGGPVVLHCQSDA-----IPPPTL--SWRKDGRPLFRKPGLTVLSDGS- 56 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYERE--YRIKRGSDVTL 1307 L + D Y+C + T+ + V P I E + G+ +T+ Sbjct: 57 -VLRVDSAQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITM 115 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + + P P+ W + +K + + + S L I TD Y + G Sbjct: 116 VCESSGIPPPSLVWRKDGSELKPTQRLR--VLSGGRQLQISSAARTDTASYSCTASSASG 173 Query: 1368 HADVEMNVTILDKPS---PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 E ++ + +PS G + + + E + + + + + + Sbjct: 174 ITSKEYSLQVYVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTW-LKDGRPVSG 232 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 V N + I+ +K + + R+ AVN +D+ + + + V Sbjct: 233 QHRAKVLNEGRL-LQIKTVKVSDTGRYTCVAVNAAGQADSRHDVS----VHVPPVITGQV 287 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXX 1542 + P +N++ + L+C G+P P ++W +DG+ ++ + + + Sbjct: 288 DVP-ENVSVVLKNPVALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGGRSLRLMHAAV 346 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C+ N GE + + I P I T+ + +K+KH + +T + G Sbjct: 347 GDGGRYTCVVSNMAGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNL----TLTCEVSG 402 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P P + W K+G L +D+ + + + + ++I + + + +Y+ ASN+AG S Sbjct: 403 NPVPGIKWLKDGQMLVSDRHHQVFSNGR--FLQIFGTRVADTGRYSCLASNSAGERSRHY 460 Query: 1659 TLKVYDKP----SKPEGPVIMREISRESVT 1684 L V P S PEG V ++ S T Sbjct: 461 NLNVLVSPTIAGSGPEGSVEEVTVTASSPT 490 Score = 75.8 bits (178), Expect = 1e-11 Identities = 86/359 (23%), Positives = 132/359 (36%), Gaps = 46/359 (12%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V +C EG PRP +TW + + ++ + L I+ V D G +TC Sbjct: 204 GGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEG---RLLQIKTVKVSDTGRYTC 260 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VA NAAG A S ++ V P G D+ E + K P Sbjct: 261 VAVNAAGQADSRHDVSVHVPPVITGQ----------------VDVPENVSVVL-KNP--- 300 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 + L C IP P I+WL G+ + ++ V L++ + Sbjct: 301 -------VALSCEASGIPLPAISWLKDGQPVRASSSVHVLSGG------RSLRLMHAAVG 347 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGN 761 G YT V N GE L I PP + E + V++ ++ L+ +V GN Sbjct: 348 DGGRYTCVVSNMAGEERKNFDLDILV----PPSIEEEGTVVDTKVKEKHNLTLTCEVSGN 403 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P P I W K+ + + + + +V D G Y+ A NS G + Sbjct: 404 PVPGIKWLKDGQMLVSDRHHQVFSNGRFLQIFGTRVADTGRYSCLASNSAGERSRHYNLN 463 Query: 822 V-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 V PT + P +E+TV L+ P +TW R+ S+ + Sbjct: 464 VLVSPTIAGSGPE---GSVEEVTVTASSPTSLLCDAQSYPPAVVTWLRDGSSFESSDHV 519 Score = 71.3 bits (167), Expect = 3e-10 Identities = 45/188 (23%), Positives = 82/188 (43%), Gaps = 4/188 (2%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXX 1539 P ++ N T + L C +P P ++W +DG+ L K + Sbjct: 3 PNIQGEELNATVMLGGPVVLHCQSDAIPPPTLSWRKDGRPLFRKPGLTVLSDGSVLRVDS 62 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y C A N G+ E + + + P I S E G+ + GI Sbjct: 63 AQVQDSGRYSCEATNVAGKTEKNYNLNVWVAPSIRGSEEPTPLTVIEGNPITMVCESSGI 122 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 PPP ++W K+G++L+ + + + + ++I R+ ++ Y+ AS+ +G +S E + Sbjct: 123 PPPSLVWRKDGSELKPTQRLRVLSGGRQ--LQISSAARTDTASYSCTASSASGITSKEYS 180 Query: 1660 LKVYDKPS 1667 L+VY +PS Sbjct: 181 LQVYVRPS 188 Score = 70.9 bits (166), Expect = 4e-10 Identities = 120/533 (22%), Positives = 200/533 (37%), Gaps = 60/533 (11%) Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ------KSYETEEG 943 L I N E D+G Y CVA+N AG++ + + V + K + + Sbjct: 558 LQILNAKEE-DAGRYTCVAANEAGETLKHYELKVFVPPHINRNDIPGEGLKPKEVKVKVN 616 Query: 944 KTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI- 1000 ++ LEC Q + + +WY + + + DH I GR D G C+ Sbjct: 617 SSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGRMVQVEHARVS--DTGRYTCVA 674 Query: 1001 --VKDQETSTMLVVKETIPEFIR--------KLQDFEVKEKDVAILE-VEINSETADV-- 1047 + ++ V + P F R E +DV + + + ET V Sbjct: 675 TNIAGEDEKDFDVNVQVPPNFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNAVPP 734 Query: 1048 ---VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102 W +DG+++ +K G + L I D G Y C+ +E+ + Sbjct: 735 PTLTWYKDGQLLA-SGDKVLILPGGRV--LQIPRAQAEDAGRYICMAVNEAGEDSIHYDV 791 Query: 1103 -VELPPEI---ITRLQNQKVNKGNKAT-FEIELTKGDA-LVRWFKDGSEIQFSNHIQLTI 1156 V LPP I ++ + NK T E A V WF+D ++ ++ Sbjct: 792 RVLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVRPDGRHRILS 851 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANT 1212 +G+ L++ + D G Y C N +A L V P + PE + V N+ Sbjct: 852 NGRI--LQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSN-PESVNVVVNS 908 Query: 1213 DAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 L+ E +P TL TW + ++ ++ RTL I K D +Y+CV Sbjct: 909 FVSLSCEATGLPPPTL--TWLNDRGPVQANTHALIMPG--GRTLQIMKAKVSDGGKYSCV 964 Query: 1270 LLDAKSTTKLKVEVVEF-PPKI----VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 ++A + + F PP I D G TL + A P P+ W N Sbjct: 965 AMNAAGEAHRHIYLTVFIPPSIRGSSGDSPVVVNTLAGKASTLECETSAVPAPSISWYKN 1024 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 +++ + + + I + L IK +D G Y + N G D ++ + Sbjct: 1025 GRVVTESANLR--ILKEGQMLEIKTTGVSDTGQYVCKATNIAGQVDKNFHLNV 1075 Score = 64.1 bits (149), Expect = 4e-08 Identities = 76/355 (21%), Positives = 138/355 (38%), Gaps = 25/355 (7%) Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--CTAEVTV-V 1103 +VW +DG +KP + R+L I + + D YSC S + E ++ V Sbjct: 127 LVWRKDGSELKPTQR---LRVLSGGRQLQISSAARTDTASYSCTASSASGITSKEYSLQV 183 Query: 1104 ELPPEIITR---LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGK 1159 + P I + V KG T + V W KDG + + ++ +G+ Sbjct: 184 YVRPSIKLSEGLSDDVAVTKGGDVTLQCAAEGIPRPAVTWLKDGRPVSGQHRAKVLNEGR 243 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDA 1214 L+I + D G Y+C N+ A + P I + +PE + V Sbjct: 244 L--LQIKTVKVSDTGRYTCVAVNAAGQADSRHDVSVHVPPVITGQVDVPENVSVVLKNPV 301 Query: 1215 YLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 L+ E L ++W K + + ++S R+L + D YTCV+ + Sbjct: 302 ALSCEASGIPLPAISWLKDGQPVRASSSVHVLSG--GRSLRLMHAAVGDGGRYTCVVSNM 359 Query: 1274 KSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + ++ + PP I + + ++K ++TL + P P +W+ + +++ Sbjct: 360 AGEERKNFDLDILVPPSIEEEGTVVDTKVKEKHNLTLTCEVSGNPVPGIKWLKDGQMLVS 419 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 +H + + S L I D G Y N+ G N+ +L P+ G Sbjct: 420 DRHHQ--VFSNGRFLQIFGTRVADTGRYSCLASNSAGERSRHYNLNVLVSPTIAG 472 Score = 64.1 bits (149), Expect = 4e-08 Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 7/186 (3%) Query: 1479 IQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXX 1536 ++ P ++ L++ EP + L C G P P + W ++G + + N Sbjct: 2326 LEPPIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQLNNGSLA 2385 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C+A ND G VE S + +Q+ P TI+ E + G ++ Sbjct: 2386 IYGTVSEDAGSYTCVATNDAGAVERSVTLTLQRAP--TITEEPVGTVVDAGSTVVLNCQA 2443 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 EG P P + W + G L + ++ + +RI +++ +++Y A N G+ Sbjct: 2444 EGEPTPTIEWSQQGRPLLGNDRFSSLS---NGSLRISSVQKEDTARYECVARNLVGSVLA 2500 Query: 1657 EVTLKV 1662 V L V Sbjct: 2501 RVPLTV 2506 Score = 57.2 bits (132), Expect = 5e-06 Identities = 98/487 (20%), Positives = 181/487 (37%), Gaps = 54/487 (11%) Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIIT--------RLQNQKVN 1119 R L I N D G Y+C+ +E+ E+ V +PP I + + KV Sbjct: 556 RTLQILNAKEEDAGRYTCVAANEAGETLKHYELKVF-VPPHINRNDIPGEGLKPKEVKVK 614 Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 + T E + ++W+KDG +Q +H+ +T G+ +++ + D G Y+C Sbjct: 615 VNSSLTLECAAQAFPSPALQWYKDGQILQVDDHMSITASGR--MVQVEHARVSDTGRYTC 672 Query: 1179 E----VGNSKCTAILTVEEPSINFTLR---------------LPEFILVPANTDAYLTVE 1219 G + + V+ P NFT + + IL + T Sbjct: 673 VATNIAGEDEKDFDVNVQVPP-NFTRAGGAAGSTSSPGVEGDVRDVILNNPISLYCETNA 731 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 +P TL TWYK ++ +K ++ R L I + +D Y C+ ++ + Sbjct: 732 VPPPTL--TWYKDGQLLASGDKVLILPG--GRVLQIPRAQAEDAGRYICMAVNEAGEDSI 787 Query: 1280 KVEV-VEFPP----KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 +V V PP + D+ E + L P P W +S+ ++ Sbjct: 788 HYDVRVLLPPIIRGTVSDFPEEVTVLVNKTTQLECHADGNPAPRVSWFQDSQPVR--PDG 845 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG-KPNILEID 1393 + I S L + + +D G Y N G A+ N+ + P G P + + Sbjct: 846 RHRILSNGRILQVLTAQVSDTGRYVCVAANVAGSAEKSFNLNVHVPPMVIGSNPESVNVV 905 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 +S E T+ ++ + + + +T I K + ++ Sbjct: 906 VNSFVSLSCEATGLPPPTLT-WLNDRGPVQANTHALIMPGGRT-LQIMKAKVSDGGKYSC 963 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 A+N + + Y V I+ + + P+ + T + L C VP P + Sbjct: 964 VAMN---AAGEAHRHIYLTVFIPPSIRGSSGDSPVV-VNTLAGKASTLECETSAVPAPSI 1019 Query: 1514 TWYRDGK 1520 +WY++G+ Sbjct: 1020 SWYKNGR 1026 Score = 56.8 bits (131), Expect = 6e-06 Identities = 40/142 (28%), Positives = 58/142 (40%), Gaps = 7/142 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ R P S+V +C V+G P P +TW + + S ++ + +L Sbjct: 2059 PVIGSDTRTYRAPTDSSVTLQCHVDGSPPPSVTWNKDGQPLAESVRRRVL----SSGSLQ 2114 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + V ED G +TC A N AG S L V+ P S G E V + Sbjct: 2115 LAFVQSEDTGRYTCTAANPAGTVSLEMSLTVQVPPSIRGGEKEV--AVVENSRVQLVCVA 2172 Query: 630 EGIP-PTFSKKPKAQYVDEGSD 650 EG+P PT S + E S+ Sbjct: 2173 EGVPQPTLSWEKDGNLFSESSE 2194 Score = 56.8 bits (131), Expect = 6e-06 Identities = 36/99 (36%), Positives = 49/99 (49%), Gaps = 8/99 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568 P+F E L G + C V G P P ITW +I+ ++YD N + L Sbjct: 2240 PVFTELLGDVALKKGERLLLACGVNGIPTPHITWVFNNSILP------VHYDHANGHSQL 2293 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPLSD 606 VI V ED+GT+TCVA+N G S + I+E P+ D Sbjct: 2294 VIERVTKEDSGTYTCVAENRVGTIKSLGFVSILEPPIID 2332 Score = 48.0 bits (109), Expect = 0.003 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 3/98 (3%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 +AP E + P + EC V G P PQ+TW + AI+ + + +D + Sbjct: 1691 VAPSIEEGSQAVSAPVNKSAVLECVVNGVPPPQVTWRKHGAILAGNNPRYRFAED---GS 1747 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 L I D G + C+A N AG +L V P S Sbjct: 1748 LHITSAQVSDTGRYLCMATNQAGIQRRRVDLQVYVPPS 1785 Score = 44.8 bits (101), Expect = 0.026 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 9/102 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT +++P VD GS ++L C+ P P I W +G ++ ++ S Sbjct: 2420 PTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSNGS------ 2473 Query: 694 VLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKE 733 L+I++V+K Y VA N G A +P+ +++ G E Sbjct: 2474 -LRISSVQKEDTARYECVARNLVGSVLARVPLTVRVHGGFSE 2514 Score = 43.6 bits (98), Expect = 0.061 Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 + S VQ C EG P+P ++W + + S + L+I EDAG +T Sbjct: 2162 ENSRVQLVCVAEGVPQPTLSWEKDGNLFSESSEEPTVLPSGE---LIITRAQAEDAGRYT 2218 Query: 583 CVAKNAAGFASSTTELIVE 601 CVA N G T L V+ Sbjct: 2219 CVATNELGQDRWTATLSVQ 2237 Score = 43.2 bits (97), Expect = 0.081 Identities = 29/92 (31%), Positives = 38/92 (41%), Gaps = 4/92 (4%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP E+ GSTV CQ EG P P I W +Q + + F + +L Sbjct: 2419 APTITEEPVGTVVDAGSTVVLNCQAEGEPTPTIEWSQQGRPLLGNDRFSSLSN----GSL 2474 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I V ED + CVA+N G + L V Sbjct: 2475 RISSVQKEDTARYECVARNLVGSVLARVPLTV 2506 Score = 42.3 bits (95), Expect = 0.14 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 5/93 (5%) Query: 510 PIFVEKLRPKHT-PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 PI LR P G C+V G P P I W + I + N +L Sbjct: 2329 PIIDGDLRSNRIEPLGGNAVLNCEVRGDPPPTIRWSKNGIHITIGDRIRQL----NNGSL 2384 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I EDAG++TCVA N AG + L ++ Sbjct: 2385 AIYGTVSEDAGSYTCVATNDAGAVERSVTLTLQ 2417 Score = 38.3 bits (85), Expect = 2.3 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 E+ P +G+ + C+ G P P + W + + +KP+Q ++ L I Sbjct: 100 EEPTPLTVIEGNPITMVCESSGIPPPSLVWRKDGSELKPTQRLRVL---SGGRQLQISSA 156 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIV 600 D +++C A +A+G S L V Sbjct: 157 ARTDTASYSCTASSASGITSKEYSLQV 183 >UniRef50_Q1JPV5 Cluster: Zgc:136545; n=3; Danio rerio|Rep: Zgc:136545 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 822 Score = 192 bits (468), Expect = 9e-47 Identities = 152/582 (26%), Positives = 253/582 (43%), Gaps = 40/582 (6%) Query: 1019 FIRKLQDFEVKEKDVAI-LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 F++KL EK I L VE+ A V W ++G+ IKP KY FE G IRKL I Sbjct: 229 FLKKLDPAYSVEKGKKIQLSVELTDPNAQVKWLKNGQEIKPSA-KYVFESVGGIRKLTIN 287 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 ++ D+ Y C++ +E EV + E P I L + V +G+K FE+E++ A V Sbjct: 288 KCTLADDAAYECVVGEEKSFTEVFIQEPPVTITKMLDDAHVVEGDKVEFEVEVSDEGANV 347 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 +W KDG E+ + DG K L I + +D G Y + A L VEE + Sbjct: 348 KWMKDGVELSRDGKYRFKKDGTKHWLIINEATTEDIGTYYVYTSGGESKAELEVEERELE 407 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 + + + V A A E+ DE + W+K + +++ + + L+I Sbjct: 408 VLQSIAD-LTVKAAEQAVFKCEVSDEKVTGKWFKDGVEVVASDRIKMSHIGRTHKLVISD 466 Query: 1258 CTEDDQCEYTCV------LLDAK-STTKLKVEVV--EFPPKI-------VDYEREYRIKR 1301 +D +YT V L AK + ++K++ V + PPKI + + + Sbjct: 467 VKPEDAGDYTFVPDGYALSLSAKLNFLEIKIDYVPRQEPPKIHLDATGSMVNKNTIIVVA 526 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYK 1359 G+ + VD P P W I + + + ++++ A I+ E +D G+Y Sbjct: 527 GNKLRFDVDITGEPPPTVAWKKGDMEISQAE-GRVRVETRKALSCFVIEGAERSDEGLYH 585 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + + N G ++ V I+D P PP L + S +I W P++ GN+ II Y V+ Sbjct: 586 ITVTNPAGEDKADVFVKIVDVPDPPENVKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQK 645 Query: 1420 QEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + T EW +V ++ + ++ +L + Y FR ++ N +S+ + ++ VI +T Sbjct: 646 ADKKTKEWFTVLEHNCRPSCTVSDLVMGNEYFFRIFSENICGMSEEAGLSKNTAVIAKTG 705 Query: 1479 IQ-------------SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----GKK 1521 +Q SP PL + + ++C G P+PK+ W ++ G+ Sbjct: 706 LQYKPQPYKEKDMNSSPKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGED 765 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 K + Y C A ND GE E C Sbjct: 766 PKFLMQNNQGVLTLNIRKPSLFDCGKYTCKAINDLGEDEVEC 807 Score = 88.6 bits (210), Expect = 2e-15 Identities = 51/174 (29%), Positives = 83/174 (47%), Gaps = 8/174 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 I G PPP V W K ++ + + T++ S I+ +RS Y I +N AG Sbjct: 536 ITGEPPPTVAWKKGDMEISQAEGRVRVETRKALSCFVIEGAERSDEGLYHITVTNPAGED 595 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 +V +K+ D P PE V + +S +IEWKPP D+G ++ Y ++K + W Sbjct: 596 KADVFVKIVDVPDPPEN-VKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQKADKKTKEWF 654 Query: 1715 KVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEAL---ESEPIVIKTAL 1764 V ++ + C + L EY FR+ ++N G SE ++ ++ KT L Sbjct: 655 TV--LEHNCRPSCTVSDLVMGNEYFFRIFSENICGMSEEAGLSKNTAVIAKTGL 706 Score = 74.9 bits (176), Expect = 2e-11 Identities = 90/371 (24%), Positives = 144/371 (38%), Gaps = 32/371 (8%) Query: 835 FINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893 F+ + EKG I+L +T +P + W +N + I PS G +L I Sbjct: 229 FLKKLDPAYSVEKGKKIQLSVELT-DPNAQVKWLKNGQEIKPSAKYVFESVGGIRKLTI- 286 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953 N + D Y+CV G+ V I VT K L ++ E G V E + S Sbjct: 287 NKCTLADDAAYECVV----GEEKSFTEVFIQEPPVTITKMLDDAHVVE-GDKVEFEVEVS 341 Query: 954 HT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012 + KW + E+S ++G D+G E+ L V Sbjct: 342 DEGANVKWMKDGVELSRDGKYRFKKDGTKHWLIINEATTEDIGTYYVYTSGGESKAELEV 401 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDG-EIIKPKKNKYDFEKRGHI 1071 +E E ++ + D VK + A+ + E++ E W +DG E++ + K R H Sbjct: 402 EERELEVLQSIADLTVKAAEQAVFKCEVSDEKVTGKWFKDGVEVVASDRIKMSHIGRTH- 460 Query: 1072 RKLYIRNTSVHDEGEYSCILRDE--SCTAEVTVVEL---------PPEIITRLQNQKVNK 1120 KL I + D G+Y+ + S +A++ +E+ PP+I VNK Sbjct: 461 -KLVISDVKPEDAGDYTFVPDGYALSLSAKLNFLEIKIDYVPRQEPPKIHLDATGSMVNK 519 Query: 1121 -------GNKATFEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLD 1171 GNK F++++T + V W K EI Q +++ I + Sbjct: 520 NTIIVVAGNKLRFDVDITGEPPPTVAWKKGDMEISQAEGRVRVETRKALSCFVIEGAERS 579 Query: 1172 DAGEYSCEVGN 1182 D G Y V N Sbjct: 580 DEGLYHITVTN 590 Score = 48.4 bits (110), Expect = 0.002 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 ++ + +P F+ L + G + C V G P+P+I W + II F M ++ Sbjct: 716 KDMNSSPKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGEDPKFLM-QNNQ 774 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAG 590 V TL IR+ D G +TC A N G Sbjct: 775 GVLTLNIRKPSLFDCGKYTCKAINDLG 801 Score = 48.0 bits (109), Expect = 0.003 Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 7/153 (4%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 IE + DE ++ I+ N G E ++ K VP PP ++ VG + Sbjct: 573 IEGAERSDEGLYHITVTNPAG-----EDKADVFVKIVDVPDPPEN-VKCLGVGEDSASIE 626 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ +G ++GY + D W V + + + DL + Y RI++ N Sbjct: 627 WKPPKDNGNTDIIGYTVQKADKKTKEWFTVLEHNCRP-SCTVSDLVMGNEYFFRIFSENI 685 Query: 2047 IGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 G+SE + VI G +P ++ ++ Sbjct: 686 CGMSEEAGLSKNTAVIAKTGLQYKPQPYKEKDM 718 Score = 42.7 bits (96), Expect = 0.11 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITI 791 P+ I PL V G S +S V G P+P I W KN + P +++ ++ I Sbjct: 722 PKFITPLVDRSVVAGYSAAISCAVRGCPKPKIIWMKNKMIIGEDPKFLMQNNQGVLTLNI 781 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 KP + D G YT KA N G E + V TE+ Sbjct: 782 RKP-SLFDCGKYTCKAINDLGEDEVECRLEVRVVTEK 817 Score = 42.7 bits (96), Expect = 0.11 Identities = 21/79 (26%), Positives = 36/79 (45%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 ++ + G P P++IW KN + D ++ + + + I++ KYT +A N Sbjct: 741 ISCAVRGCPKPKIIWMKNKMIIGEDPKFLMQNNQGVLTLNIRKPSLFDCGKYTCKAINDL 800 Query: 1652 GTSSVEVTLKVYDKPSKPE 1670 G VE L+V K E Sbjct: 801 GEDEVECRLEVRVVTEKEE 819 Score = 41.1 bits (92), Expect = 0.33 Identities = 43/178 (24%), Positives = 73/178 (41%), Gaps = 21/178 (11%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VL 725 W G E+V + I ++ H L I++VK G YT V S + L Sbjct: 438 WFKDGVEVVASDRIKMSHIGRTHK----LVISDVKPEDAGDYTFVPDGYALSLSAKLNFL 493 Query: 726 KIKTG---EKEPPQV-IEPLKSM------IVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 +IK +EPP++ ++ SM IV G + + G P PT+ W K + + Sbjct: 494 EIKIDYVPRQEPPKIHLDATGSMVNKNTIIVVAGNKLRFDVDITGEPPPTVAWKKGDMEI 553 Query: 776 KALPTKSDGDTH---SITILKPKKVKDEGVYTLKAENSEGIAETSA---VITVEEPTE 827 + +T S +++ + DEG+Y + N G + ++ V +P E Sbjct: 554 SQAEGRVRVETRKALSCFVIEGAERSDEGLYHITVTNPAGEDKADVFVKIVDVPDPPE 611 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 3/101 (2%) Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 P D K + P P N S +++W P+ NG + I Y ++ K Sbjct: 591 PAGEDKADVFVKIVDVPDPPENVKCLGVGEDSASIEWKPPKDNGNTDIIGYTVQKADKKT 650 Query: 1910 KSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVS 1949 K W ++ + C + ++ +E FRI +EN G+S Sbjct: 651 KEWFTVLE--HNCRPSCTVSDLVMGNEYFFRIFSENICGMS 689 Score = 36.7 bits (81), Expect = 7.0 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 8/125 (6%) Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 + I+ + E ++ + NP G E + V +DVP + +S Sbjct: 571 FVIEGAERSDEGLYHITVTNPAG-----EDKADVFVKIVDVPDPPENVKCLG-VGEDSAS 624 Query: 1786 ITWFPSEKNGGSPIIDYKVE-IKQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 I W P + NG + II Y V+ ++ K+W + L + Y FRI++ N Sbjct: 625 IEWKPPKDNGNTDIIGYTVQKADKKTKEWFTVLEHNCRPSCTVSDLVMGNEYFFRIFSEN 684 Query: 1844 EIGTS 1848 G S Sbjct: 685 ICGMS 689 >UniRef50_Q5VST9 Cluster: Obscurin; n=50; Amniota|Rep: Obscurin - Homo sapiens (Human) Length = 7968 Score = 192 bits (467), Expect = 1e-46 Identities = 166/673 (24%), Positives = 287/673 (42%), Gaps = 42/673 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ +P F++ + + EG+ +L C L + + W KG E + D + + + Sbjct: 3445 VKALPAKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWR-KGPENLRDGDRYILRQEGT 3501 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 C L+I + G Y V A+L I P + IE +K+ R+ Sbjct: 3502 R--CE-LQICGLAMADAGEYLCVCGQERTSATLTI-------RALPARFIEDVKNQEARE 3551 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G + +L ++ N + W K ++ ++ + DG + I + + D G Y+ Sbjct: 3552 GATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQI-RGLAMADTGEYSC 3608 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 G TSA++TV A P F + E T V R + + + Sbjct: 3609 VC----GQERTSAMLTVR------ALPIKFTEGLRNEEATEGATA--VLRCELSKMAPVE 3656 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W++ +E + + + DG EL I + +E D+G+Y C+ GK A +T+ Sbjct: 3657 WWKGHETLRDGDRHSLRQDGARCELQIRGLVAE-DAGEYLCMC----GKERTSAMLTVRA 3711 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 F++ L+ E EG T L C+ S +W + + D + Q+G Sbjct: 3712 MPSKFIEGLRNE-EATEGDTATLWCELSKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G C+ + TS L V+ FI +++ E +E A+L+ E+ S+ A Sbjct: 3771 IRGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCEL-SKAA 3829 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 V W + E ++ ++Y + G +L I SV D GEYSC+ E +A +TV Sbjct: 3830 PVEWRKGSETLRGG-DRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAP 3888 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P LQ+ + +G+ AT + EL++ A V W K G ++Q + + + G +L + Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 D +D GEY+C G+ +A LTV + F LR + V A+L E+ Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRF-LRELQHQEVDEGGTAHLCCELSRAGA 4007 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-- 1283 V W K + K+ ++ D L++R ++D +YTC +S L V V Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPR 4067 Query: 1284 VEFPPKIVDYERE 1296 +F ++ E+E Sbjct: 4068 PKFKTRLQSLEQE 4080 Score = 189 bits (461), Expect = 6e-46 Identities = 271/1259 (21%), Positives = 487/1259 (38%), Gaps = 118/1259 (9%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F L+ T + V EC++ P + W + ++ + + + + R Sbjct: 2168 FSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYR 2226 Query: 572 EVFPEDAGTFTCVAKNAAGFAS-----STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 F D G + C A +A AS T LI L++ E+ Sbjct: 2227 CEFA-DQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLR- 2284 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 ++ +P T + + + E +LEC+ V+ + W +E+ P + + Sbjct: 2285 --VKELPVTLVRPLRDKIAMEKHRGVLECQ-VSRASAQVRWFKGSQELQPGPKYELVSDG 2341 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 +Y ++ I++V E TYT A + + A + E++ ++ L+ + V Sbjct: 2342 ---LYRKLI-ISDVHAEDEDTYTCDAGDVKTSAQFFV-------EEQSITIVRGLQDVTV 2390 Query: 747 RQGESVILSAQV-VGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802 + + + + RP W ++A + + +G H + + + V Sbjct: 2391 MEPAPAWFECETSIPSVRPP-KWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPV 2449 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 + + G + +SA + V + P + + T +E ++ L P Sbjct: 2450 HF-----TVGKSRSSARLVVSDI------PVVLTRPLEPKTGRELQSVVLSCDFRPAP-K 2497 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 ++ WY+++ +SPSE + +G+ EL I + D+G Y+C AG + VT Sbjct: 2498 AVQWYKDDTPLSPSEKFKMSLEGQMAELRILRL-MPADAGVYRC----QAGSAHSSTEVT 2552 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 ++ +VT LQ + TEEG C+ SH +W N + EI +GR Sbjct: 2553 VEAREVTVTGPLQDAEATEEG-WASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G+++ TS L V+ F++ L D +E+ L+ E++ Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 A VVW +DG + P +KYDF R L + + S D G Y+C + E A V Sbjct: 2672 DPEAHVVWRKDGVQLGPS-DKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVR 2730 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159 V +L I RL+ +V +G +FE L+ A W G + S+ Q T G+ Sbjct: 2731 VHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGR 2790 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 K L + + DAGE V A L V E L + + P D L E Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGE-DVELRCE 2849 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + V W K + I ++K+ ++ + L+IR + D EYTC + +KST L Sbjct: 2850 LSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTASL 2909 Query: 1280 KVEVVE--FPPKIVDYEREYRIKRGSDV-TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 VE F ++ + + E ++G+ V T ++ P W ++ +P Sbjct: 2910 HVEEKANCFTEELTNLQVE---EKGTAVFTCKTEH---PAATVTWRKGLLELRASGKHQP 2963 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 S + + LTI +E D+ Y + G A + + + + +I+E D Sbjct: 2964 SQEGLTLRLTISALEKADSDTYTCDI----GQAQSRAQLLVQGR-----RVHIIE-DLED 3013 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 +++ G+S + + W K T + N + + Sbjct: 3014 VDV------QEGSSATFRCRISPANYEPVHWFLDK--TPLHANELNEIDAQPGGYHVLTL 3065 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTV-EKP------LKNITTEPNEDIELTCIFGGVP 1509 ++ + D+ T Y++ + + V EKP L + T ED+ L C Sbjct: 3066 RQLALKDSG--TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCD 3123 Query: 1510 QPKVTWYRDGKKLKTA---KATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P V W +DGK L+ + + ++E +R YKC A G +S +V Sbjct: 3124 IP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIV 3178 Query: 1566 GIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 + +PV E +K + G + V+ + P V W N L +Y++ + Sbjct: 3179 RVHARPVRF--QEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQE 3235 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 + ++ L+ S +Y S + G + TL V P++ G + +E + Sbjct: 3236 GAMLELVVRNLRPQDSGRY----SCSFGDQTTSATLTVTALPAQFIGKLRNKEAT----- 3286 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 +G + + K P W K ++ RD + YC+++ CE R +A Sbjct: 3287 --------EGATATLRCELSKAAPVE--WRKGSETLRDGDRYCLRQDGAMCELQIRGLA 3335 Score = 180 bits (437), Expect = 5e-43 Identities = 169/669 (25%), Positives = 275/669 (41%), Gaps = 39/669 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L I+ ++K TYT + A L + + +IE L+ + V++G S Sbjct: 2972 LTISALEKADSDTYTCDIGQAQSRAQLLV-------QGRRVHIIEDLEDVDVQEGSSATF 3024 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENS 810 ++ + W + P+ A G H +T L+ +KD G +A Sbjct: 3025 RCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLT-LRQLALKDSGTIYFEA--- 3080 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G SA + V E +P +F + T+ E + LV + +P + W ++ Sbjct: 3081 -GDQRASAALRVTE------KPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDG 3132 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + + S + +G +L+IT + DSG YKC A + S V + V F Sbjct: 3133 KTLRGSARCQLSHEGHRAQLLITGATLQ-DSGRYKCEAGGACSSSI----VRVHARPVRF 3187 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 + L K E EG L C S + KW + + D + QEG Sbjct: 3188 QEAL-KDLEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNL 3246 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 D G C DQ TS L V +FI KL++ E E A L E+ S+ A V W Sbjct: 3247 RPQDSGRYSCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCEL-SKAAPVEW 3305 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 + E ++ ++Y + G + +L IR ++ D EYSC+ +E +A +T+ +P Sbjct: 3306 RKGSETLRDG-DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHF 3364 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 I RL++Q+ +G AT EL+K A V W K ++ + L DG +L+I Sbjct: 3365 IGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDGDRHSLRQDGAVCELQICGLA 3423 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 + DAGEYSC G + +A LTV+ FT L V T A L E+ + V W Sbjct: 3424 VADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGAT-AMLWCEL-SKVAPVEW 3481 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 K + D +++ L + + L I D EY CV +++ L + + P + Sbjct: 3482 RKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL--PAR 3539 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 ++ + + G+ L + + EW S+ ++ D L I+ Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAAPV--EWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597 Query: 1350 VENTDAGIY 1358 + D G Y Sbjct: 3598 LAMADTGEY 3606 Score = 170 bits (414), Expect = 3e-40 Identities = 196/889 (22%), Positives = 349/889 (39%), Gaps = 58/889 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESD 687 + +P F + K Q EG+ +L+C L A P + W E + + S+ + Sbjct: 3797 VRALPARFIEDVKNQEAREGATAVLQCELSKAAP---VEWRKGSETLRGGDRYSLRQDGT 3853 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 C L+I + G Y+ V A+L + P EPL+S+ Sbjct: 3854 R---CE-LQIHGLSVADTGEYSCVCGQERTSATLTV-------RAPQPVFREPLQSLQAE 3902 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYT 804 +G + L ++ P T+ W K ++A + G T + +L+ + +D G YT Sbjct: 3903 EGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRLQGCTAEL-VLQDLQREDTGEYT 3960 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 G TSA +TV A P F+ Q V E GT L ++R S+ Sbjct: 3961 CTC----GSQATSATLTV------TAAPVRFLRELQHQEVDEGGTAHLCCELSRAGA-SV 4009 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + + + P DG EL++ V+ E D+GDY C G + A +++ Sbjct: 4010 EWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQE-DAGDYTC----DTGHTQSMASLSVR 4064 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKEISGMDHREIIQEGRX 981 V + F LQ S E E G L CQ S S +W E+ E+ +G Sbjct: 4065 VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT 4123 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D G C+ Q+T+ L V E +R L D EV + E++ Sbjct: 4124 RELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVS 4183 Query: 1042 SETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 A V W G ++ + + G I L ++ + D G S L + + +A++ Sbjct: 4184 RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQL 4243 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTID-G 1158 TV I+ LQ+ ++++G A+F+ L++ RW G +Q + +T++ G Sbjct: 4244 TVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQG 4303 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 L ++ L+DAG S VG C++ ++ + N +R E + +A Sbjct: 4304 TLHLLTLHKVTLEDAGTVSFHVGT--CSSEAQLKVTAKNTVVRGLENVEALEGGEALFEC 4361 Query: 1219 EIPD-ETLDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 ++ E TW + +E ++ + + L+++ D C T + D + Sbjct: 4362 QLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVT 4421 Query: 1276 TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPNDEWIVNSKIIKKCKHT 1334 + L V +I++ + ++ G+ +A P W +N ++ Sbjct: 4422 SAFLTVRGWRL--EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSD 4479 Query: 1335 -KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393 + D +L ++ + AG + C A +T+L P PP ++ Sbjct: 4480 WTVTADGSHHALLLRSAQPHHAG----EVTFACRDAVASARLTVLGLPDPPEDAEVVARS 4535 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFR 1452 S ++ + W P + G + Y VE +E T +W + + + + + L +YRFR Sbjct: 4536 SHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFR 4595 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 AV V + + ++ + K P P ++ ED+ L Sbjct: 4596 VAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAP-ESRQVAAGEDVSL 4643 Score = 161 bits (392), Expect = 1e-37 Identities = 179/903 (19%), Positives = 342/903 (37%), Gaps = 56/903 (6%) Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 +DEG Y+ + G + V EP A+ L + Q E G ++ Sbjct: 863 QDEGTYSCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQA----EAGASATLSCEV 914 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 +TWY++ + +S S + G LV+ + D+G+Y C AG Sbjct: 915 AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQA-GQADAGEYSC----EAGGQRL 969 Query: 918 GARVTIDVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHRE 974 + + KV F K + E G + L C+ + WY + K++S Sbjct: 970 SFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQTEVMWYKDGKKLSSSLKVH 1029 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL---QDFEVKEK 1031 + +G D G C + Q S L + E F ++ + + + Sbjct: 1030 VEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAG 1089 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 A+L E+ +V W +DG+ + +K E +G R+L + D GEYSC Sbjct: 1090 ASAMLSCEVAQAQTEVTWYKDGKKLS-SSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA 1148 Query: 1092 RDESCTAEVTVVELPPEIITRLQN----QKVNKGNKATFEIELTKGDALVRWFKDGSEIQ 1147 + + + + E P + + Q+ + G A E+ + V W+KDG ++ Sbjct: 1149 GGQRVSFHLHITE-PKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLS 1207 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEF 1205 S+ +++ + G ++L + DAGEYSCE G + + L + EP F + Sbjct: 1208 SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNE 1267 Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 + A A L+ E+ +VTWYK + + K + + R L++++ + D E Sbjct: 1268 VRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGE 1327 Query: 1266 YTCVLLDAKSTTKLKV-EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 YTC + + L V E K R+ + + G+ TL + A Q W + Sbjct: 1328 YTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKD 1386 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDKPS 1382 K + + + L +++ D G Y + DV + K Sbjct: 1387 GKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQ 1446 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 P + + +S+ C E T + + + +++ + + ++ + T+ + Sbjct: 1447 PVHREVQAQAGASTTLSC----EVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQ 1502 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 + E S+ ++ + E K + + + E L+ Sbjct: 1503 QAGQA-------VAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLS 1555 Query: 1503 CIFGGVPQPKVTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 C Q +VTWY+DGKKL ++K E Y C A G+ Sbjct: 1556 CEVAQA-QTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GD 1610 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDK 1617 S + + + V+ + ++ + T E EV WYK+G KL + Sbjct: 1611 QRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSS 1670 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASN---TAGTSSVEVTLKVYDKPSKPEGPVI 1674 + + T + +++ ++ + +Y+ EA + E+ ++ ++P + E P++ Sbjct: 1671 KVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISERPCRRE-PLV 1729 Query: 1675 MRE 1677 ++E Sbjct: 1730 VKE 1732 Score = 161 bits (392), Expect = 1e-37 Identities = 200/904 (22%), Positives = 364/904 (40%), Gaps = 67/904 (7%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +P F++ + + EG+ +L C L + + W +KG E + D + ++ D Sbjct: 3621 VRALPIKFTEGLRNEEATEGATAVLRCELSKMAP--VEW-WKGHETLRDGDRH-SLRQD- 3675 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 C L+I + G Y + A L + P + IE L++ + Sbjct: 3676 GARCE-LQIRGLVAEDAGEYLCMCGKERTSAMLTV-------RAMPSKFIEGLRNEEATE 3727 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKA 807 G++ L ++ + + W K ++ ++ DGD HS+ + +++ G+ + A Sbjct: 3728 GDTATLWCEL--SKAAPVEWRKGHETLR------DGDRHSLRQDGSRCELQIRGLAVVDA 3779 Query: 808 ENSE---GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 G TSA +TV A P FI + +E T L +++ + Sbjct: 3780 GEYSCVCGQERTSATLTVR------ALPARFIEDVKNQEAREGATAVLQCELSK--AAPV 3831 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + +E + + + DG EL I + S D+G+Y CV G+ A +T+ Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGL-SVADTGEYSCVC----GQERTSATLTVR 3886 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXX 983 + F + LQ S + EEG T L+C+ S T + W ++ RE +G Sbjct: 3887 APQPVFREPLQ-SLQAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAE 3945 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D G C Q TS L V F+R+LQ EV E A L E++ Sbjct: 3946 LVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRA 4005 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 A V W + + P KY + G +L +R D G+Y+C A ++V Sbjct: 4006 GASVEWRKGSLQLFPCA-KYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVR 4064 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P+ TRLQ+ + G+ A +L+ + A+V+W K+G E+ ++ G + Sbjct: 4065 VPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 +L I+ + D GEY+C G K A L V EP + L + V A+ D + E+ Sbjct: 4125 ELLIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVD-AEVTADEDVEFSCEVS 4183 Query: 1222 DE-TLDVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 V W + ++ E + + D + TL ++ T +D + L + S+ +L Sbjct: 4184 RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQL 4243 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 V E I++ ++ ++ G D + W + ++ + +++ Sbjct: 4244 TVRAPEV--TILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVE 4301 Query: 1340 SKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI--LEIDSSS 1396 + LT+ KV DAG + C ++ ++ VT G N+ LE + Sbjct: 4302 QGTLHLLTLHKVTLEDAGTVSFHV-GTCS-SEAQLKVT-AKNTVVRGLENVEALEGGEAL 4358 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 +PE ++ ++ + + E + +N + ++NL+ S R A Sbjct: 4359 FECQLSQPEVAAHTWLLDDEPVHTS-ENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAG 4417 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG-GVPQPKVTW 1515 + V T + ++ +++ + +PLKN TC VP + +W Sbjct: 4418 DMV--------TSAFLTVRGWRLE---ILEPLKNAAVRAGAQACFTCTLSEAVPVGEASW 4466 Query: 1516 YRDG 1519 Y +G Sbjct: 4467 YING 4470 Score = 161 bits (390), Expect = 3e-37 Identities = 157/735 (21%), Positives = 292/735 (39%), Gaps = 46/735 (6%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + G+ +L C VA + ++ W G+++ + + ++ L + K Sbjct: 1087 EAGASAMLSCE-VAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRR----LVLPQAGKADA 1141 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G Y+ A + L I KE Q + + G + +LS +V P+ Sbjct: 1142 GEYSCEAGGQRVSFHLHITEPKGVFAKE--QSVH--NEVQAEAGTTAMLSCEVA-QPQTE 1196 Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +TW K+ K + + + + G T + + + K D G Y+ +A G S + + Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKA-DAGEYSCEA----GGQRVSFQLHI 1251 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 EP A+ L N E+ + + L V + +TWY++ + +S S + Sbjct: 1252 TEPKAVFAKEQLVHN---EVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIE 1307 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH--LQKSYET 940 G +LV+ + D+G+Y C AG + + K F K + + Sbjct: 1308 AAGCMRQLVVQQA-GQADAGEYTC----EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQA 1362 Query: 941 EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 E G L C+ + WY + K++S + G D G C Sbjct: 1363 EAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC 1422 Query: 1000 IVKDQETSTMLVVKETIPEFIRKL---QDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 Q S L V E F ++ ++ + + L E+ +V+W +DG+ + Sbjct: 1423 EAGGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKL 1482 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQ-- 1114 +K E G R+L ++ GEYSC + + + V E P + + Q Sbjct: 1483 S-FSSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAE-PKAVFAKEQPA 1540 Query: 1115 --NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 + G AT E+ + V W+KDG ++ S+ +++ G ++L + + D Sbjct: 1541 SREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQAD 1600 Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF--ILVPANTDAYLTVEIPDETLDVTWY 1230 AGEYSC+ G+ + + L V EP + F P + A A L+ E+ +VTWY Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWY 1660 Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290 K + + K + + R L++++ + + EY+C +++V E P+I Sbjct: 1661 KDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA--GGQQLSFRLQVAELEPQI 1718 Query: 1291 VD--YERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 + RE +K D+ L W+ + I++ K + + + +LT+ Sbjct: 1719 SERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTV 1778 Query: 1348 KKVENTDAGIYKLRL 1362 + D+ IY R+ Sbjct: 1779 HGAQVLDSAIYSCRV 1793 Score = 152 bits (369), Expect = 9e-35 Identities = 142/641 (22%), Positives = 260/641 (40%), Gaps = 32/641 (4%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 + G+ L C VA + ++ W G+++ + V L + + + Sbjct: 1639 EAGASATLSCE-VAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRR----LVVQQAGQAEA 1693 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G Y+ A ++ L + +++ E P EPL +V++ E +IL+A + T Sbjct: 1694 GEYSCEAGGQQLSFRLQVA-ELEPQISERPCRREPL---VVKEHEDIILTATLATPSAAT 1749 Query: 766 ITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +TW K+ + K T S GDTH++T+ +V D +Y+ + +EG + V Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTV-HGAQVLDSAIYSCRV-GAEG---QDFPVQV 1804 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 EE + F + + + GT+ L ++ + W N + + Sbjct: 1805 EEVAAK------FCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMV 1857 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 +G L + + +E D+G+Y C + + A++T+ V +V + EE Sbjct: 1858 AEGPVRSLTVLGLRAE-DAGEYVCESRDD----HTSAQLTVSVPRVVKFMSGLSTVVAEE 1912 Query: 943 GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 G +C S + V+ W+ + + + I Q G D G I Sbjct: 1913 GGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEA 1972 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 + +S L V+E F +KL+ V+E+ LEVE+ ++ W R+ + P KN Sbjct: 1973 EGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKN 2032 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 + G +L + N D G + C D+ A++TV ++ LQ + + Sbjct: 2033 -VEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQ 2091 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 AT E++L+ D W +DG Q L + G L + +D+G + Sbjct: 2092 GTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAE 2151 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 +A L V E ++F+ L + ++ L E+ +DV W K + + Sbjct: 2152 GVHTSARLVVTELPVSFSRPLQD-VVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKT 2210 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + + R+L I +C DQ Y C DA+S+ +KV+ Sbjct: 2211 MAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQ 2251 Score = 138 bits (334), Expect = 2e-30 Identities = 135/567 (23%), Positives = 235/567 (41%), Gaps = 35/567 (6%) Query: 632 IPPTFSKKP---KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + P S++P + V E DI+L L + WL G EI + A + D Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 H L + + Y+ V EG+ P+ +++ + +++EP+ + Sbjct: 1774 H----TLTVHGAQVLDSAIYSC-RVGAEGQ-DFPV--QVEEVAAKFCRLLEPVCGEL--- 1822 Query: 749 GESVILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 G +V L+ ++ + C N + K ++G S+T+L + +D G Y + Sbjct: 1823 GGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLG-LRAEDAGEYVCE 1881 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 + + TSA +TV P F++ + +E G V+ + V ++ W Sbjct: 1882 SRDDH----TSAQLTVSVPRVVK-----FMSGLSTVVAEEGGEATFQCVVSPSDV-AVVW 1931 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +R+ ++ PSE + G + L I+++ E D+G + + G SS A + + Sbjct: 1932 FRDGALLQPSEKFAISQSGASHSLTISDLVLE-DAGQ---ITVEAEGASSSAA-LRVREA 1986 Query: 927 KVTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 V F K L+ EE +V LE + T +W N ++ + EI EG Sbjct: 1987 PVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G C D +T L V+ +R LQ E +E+ A +EV+++ Sbjct: 2046 LHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQLSHADV 2105 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 D W RDG + + RG + L + D G +A + V EL Sbjct: 2106 DGSWTRDGLRFQQGPTCH-LAVRGPMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTEL 2164 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P LQ+ + K T E EL++ + VRW KDG E++ + + G + L I Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVE 1192 Y C+ D G Y C+ +++ +A + V+ Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQ 2251 Score = 134 bits (325), Expect = 2e-29 Identities = 164/758 (21%), Positives = 285/758 (37%), Gaps = 49/758 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F K +E + L+C V+ PE + W G ++ P + + Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCE-VSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRG-- 2702 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L + +V G YT + E A + V + G + + LK+M V +GES Sbjct: 2703 --LVVHDVSPEDAGLYTCHVGSEETRARVR-VHDLHVG------ITKRLKTMEVLEGESC 2753 Query: 753 ----ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 +LS + +P K G + I +++ D G Sbjct: 2754 SFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKY-ILVVREAAPSDAGEVVFSVR 2812 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G+ +++I E P I ++ V ++L ++R P + W + Sbjct: 2813 ---GLTSKASLIVRERPAA-------IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLK 2861 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + I S+ +G LVI + D+G+Y C A KS+ A + ++ + Sbjct: 2862 DRKAIRKSQKYDVVCEGTMAMLVIRGASLK-DAGEYTCEVE--ASKST--ASLHVEEKAN 2916 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F + L + + EE T + C+T H +T W E+ + QEG Sbjct: 2917 CFTEELT-NLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTIS 2975 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D C + ++ L+V+ I L+D +V+E A I+ + Sbjct: 2976 ALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISPANYEP 3035 Query: 1048 V-WERDGEIIKPKK-NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 V W D + + N+ D + G+ L +R ++ D G D+ +A + V E Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGY-HVLTLRQLALKDSGTIYFEAGDQRASAALRVTEK 3094 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P L + + +G T E + D V W KDG ++ S QL+ +G + +L I Sbjct: 3095 PSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLI 3154 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 L D+G Y CE G + ++I+ V + F L + ++ A L + Sbjct: 3155 TGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA-ATLRCVLSSVAA 3213 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 V W +V+ +K++L + L++R D Y+C D TT + V Sbjct: 3214 PVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGD--QTTSATLTVTA 3271 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P + + R G+ TL + +A P EW S+ ++ D Sbjct: 3272 LPAQFIGKLRNKEATEGATATLRCELSKAAPV---EWRKGSETLRDGDRYCLRQDGAMCE 3328 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 L I+ + DA Y CG ++TI P+ Sbjct: 3329 LQIRGLAMVDAAEYSC----VCGEERTSASLTIRPMPA 3362 Score = 131 bits (316), Expect = 2e-28 Identities = 147/691 (21%), Positives = 264/691 (38%), Gaps = 38/691 (5%) Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 E GT ++ +TWY++ + +S S + G LV+ + D+G+Y Sbjct: 1547 EAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEA-GQADAGEYS 1605 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYH 962 C AG + + KV F K + + E G + L C+ + WY Sbjct: 1606 C----KAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYK 1661 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK 1022 + K++S + G + G C Q+ S L V E P+ + Sbjct: 1662 DGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEAGGQQLSFRLQVAELEPQISER 1721 Query: 1023 ---LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 + VKE + IL + + +A V W +DG I+ K +++ +G L + Sbjct: 1722 PCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSK-RHETASQGDTHTLTVHG 1780 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR 1138 V D YSC + E V V E+ + L+ G T EL+ A V Sbjct: 1781 AQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVV 1840 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS-IN 1197 W ++++ Q+ +G + L + +DAGEY CE + +A LTV P + Sbjct: 1841 WRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK 1900 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 F L + + V P + + V W++ ++++ +EKF + +L I Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGASHSLTISD 1959 Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 +D + T A S+ L+V E P ++ S VTL V+ P P Sbjct: 1960 LVLEDAGQITVEAEGASSSAALRVR--EAPVLFKKKLEPQTVEERSSVTLEVELTR-PWP 2016 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W N+ + K+ + + L + V D G + ++ A + + + Sbjct: 2017 ELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQ 2076 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 + E ++++ + + G+ T + +Q+ T ++V+ T Sbjct: 2077 VRLVRGLQAVEAREQGTATMEVQLSHADVDGSWT--RDGLRFQQGPTCH-LAVRGPMHTL 2133 Query: 1438 TSIQNLKTNSS--YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 T + L+ S F+A V+ T V+ E + + +PL+++ T Sbjct: 2134 T-LSGLRPEDSGLMVFKAEGVH----------TSARLVVTELPV---SFSRPLQDVVTTE 2179 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK 1526 E + L C P V W +DG +L+ K Sbjct: 2180 KEKVTLECELSR-PNVDVRWLKDGVELRAGK 2209 Score = 126 bits (305), Expect = 5e-27 Identities = 122/542 (22%), Positives = 224/542 (41%), Gaps = 23/542 (4%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTL 805 G S LS +V + +TW K+ K + + + ++ G T + + + + D G Y+ Sbjct: 1549 GTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQA-DAGEYSC 1606 Query: 806 KAENSEGIAETSAVITVEEPTEENA-EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 KA G S + V EP A E P +E+ + + L V + + Sbjct: 1607 KA----GDQRLSFHLHVAEPKVVFAKEQPAH----REVQAEAGASATLSCEVAQAQT-EV 1657 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TWY++ + +S S + G LV+ + ++G+Y C A + S +V Sbjct: 1658 TWYKDGKKLSSSSKVRVEAVGCTRRLVVQQA-GQAEAGEYSCEAGGQ--QLSFRLQVAEL 1714 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 +++ ++ +E + +IL T + W + EI E +G Sbjct: 1715 EPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTH 1774 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D + C V + + V+E +F R L+ + L E++ Sbjct: 1775 TLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSP 1834 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 A+VVW ++ K ++ G +R L + D GEY C RD+ +A++TV Sbjct: 1835 ACAEVVWRCGNTQLRVGK-RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTV 1893 Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V + ++ L +G +ATF+ ++ D V WF+DG+ +Q S ++ G Sbjct: 1894 SVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASH 1953 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 L I D L+DAG+ + E + +A L V E + F +L E V + L VE+ Sbjct: 1954 SLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKL-EPQTVEERSSVTLEVELT 2012 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 ++ W + + + + + ++ + L++ D+ + C D K+ KL V Sbjct: 2013 RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTV 2072 Query: 1282 EV 1283 E+ Sbjct: 2073 EM 2074 Score = 122 bits (293), Expect = 1e-25 Identities = 206/1051 (19%), Positives = 385/1051 (36%), Gaps = 70/1051 (6%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 K P+ V G D + C +A+P + WL EE+V ++++ E H L I Sbjct: 425 KLPRKTAVRVG-DTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRH----TLTI 479 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSA 756 + G +A G+ + K P Q ++P+ R SVILS Sbjct: 480 SQCCLEDVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVK--ARMESSVILSW 533 Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPK----KVKDEGVYTLKAENSE 811 + +T K L T + H + P+ V +EG + + Sbjct: 534 SPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALN 593 Query: 812 GIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 ++ + E P + P L + + + E G + +T + W+ + Sbjct: 594 SFGQSPYL---EFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLT--VASAGEWFLDG 648 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN--SAGKSSHGARVTIDVEKV 928 + + S + D L I V + + K VA+ S+ + A + K Sbjct: 649 QALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKP 708 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 + E ++ E + + W + + +S E+ Sbjct: 709 PAAAAREVLARLHEEAQLLAEL-SDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRD 767 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQD---FEVKEKDVAILEVEINSETA 1045 D G+ +C+ + + L V + + F+ K + A E E + Sbjct: 768 VARDDAGLYECVSRGGRIAYQLSV-QGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHV 826 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 V W +DG + ++ E G +L + DEG YSC + ++S + V E Sbjct: 827 HVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSE- 885 Query: 1106 PPEII---TRLQNQKVNK--GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 P+++ +L +K+ G AT E+ + V W+KDG ++ S+ + + G Sbjct: 886 -PKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCT 944 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTV 1218 ++L + DAGEYSCE G + + L V+EP + F + A A L+ Sbjct: 945 RRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSC 1004 Query: 1219 EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 E+ +V WYK + + K + + +R L++++ + D +Y+C + + + Sbjct: 1005 EVAQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFR 1064 Query: 1279 LKV-EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 L + E K E + + G+ L + A Q W + K + Sbjct: 1065 LHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEV-AQAQTEVTWYKDGKKLSSSSKVGME 1123 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 + + L + + DAG Y G V ++ I + P G + + S Sbjct: 1124 VKGCTRRLVLPQAGKADAGEYSC----EAGGQRVSFHLHITE---PKG---VFAKEQSVH 1173 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 N + G + ++ V + + T + K ++ + +K + R V Sbjct: 1174 N---EVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVK-GCTRRLVVQQVG 1229 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTV----EKPLKN-ITTEPNEDIELTCIFGGVPQPK 1512 + D + S +V + I P E+ + N + TE L+C Q + Sbjct: 1230 KADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQA-QTE 1288 Query: 1513 VTWYRDGKKL-KTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 VTWY+DGKKL ++K E Y C A G S + + Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA----GGQRLSFHLDVS 1344 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 + + + +K + + T E EV WYK+G KL + + + T Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + +++ ++ + +Y+ EA + S++V Sbjct: 1405 RRLVVQQACQADTGEYSCEAGGQRLSFSLDV 1435 Score = 122 bits (293), Expect = 1e-25 Identities = 150/720 (20%), Positives = 283/720 (39%), Gaps = 38/720 (5%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-LKITNVKKFQ 704 + G+ L C VA + ++ W G+++ + V +E+ + C+ L + + Sbjct: 1547 EAGTSATLSCE-VAQAQTEVTWYKDGKKL--SSSSKVRMEA---VGCTRRLVVQEAGQAD 1600 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y+ A ++ L + KE P E + G S LS +V + Sbjct: 1601 AGEYSCKAGDQRLSFHLHVAEPKVVFAKEQPAHRE----VQAEAGASATLSCEVA-QAQT 1655 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 +TW K+ K + + + ++ G T + + + + + G Y+ +A G + S + Sbjct: 1656 EVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQA-EAGEYSCEA----GGQQLSFRLQ 1710 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V E + +E P R + + VKE I L A + ++TW ++ I S+ Sbjct: 1711 VAELEPQISERPC---RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHET 1767 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 G+ L + +DS Y C G V ++ F + L+ E Sbjct: 1768 ASQGDTHTLTVHGAQV-LDSAIYSC----RVGAEGQDFPVQVEEVAAKFCRLLEPVCG-E 1821 Query: 942 EGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G TV L C+ S + W ++ +++ EG D G C Sbjct: 1822 LGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881 Query: 1001 VKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 +D TS L V + +F+ L +E A + ++ VVW RDG +++P Sbjct: 1882 SRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVAVVWFRDGALLQPS 1941 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 + K+ + G L I + + D G+ + S +A + V E P +L+ Q V Sbjct: 1942 E-KFAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVE 2000 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 + + T E+ELT+ +RW ++ + + ++++ +G + +L +++ D G + CE Sbjct: 2001 ERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGFFGCE 2060 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 + K A LTVE + L + + A + V++ +D +W + + Sbjct: 2061 TPDDKTQAKLTVEMRQVRLVRGL-QAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQG 2119 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKIVDYEREYR 1298 L TL + +D ++ A+ T ++ V E P ++ Sbjct: 2120 PTCHLAVRGPMHTLTLSGLRPEDS---GLMVFKAEGVHTSARLVVTELPVSFSRPLQDVV 2176 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 VTL + P + W+ + ++ K + SLTI + E D G+Y Sbjct: 2177 TTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVY 2235 Score = 115 bits (277), Expect = 1e-23 Identities = 136/655 (20%), Positives = 244/655 (37%), Gaps = 46/655 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSIT 790 P PL+ ++ + E V L ++ P + W K+ ++A T + G S+T Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAV----------ITVEEPTE-----ENAE---- 831 I + + D+GVY A +++ A + E+ E ENAE Sbjct: 2224 IYRCE-FADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQ 2282 Query: 832 ------PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 P + ++ EK L +V+R + W++ ++ + P DG Sbjct: 2283 LRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASA-QVRWFKGSQELQPGPKYELVSDG 2341 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 +L+I++V +E D Y C AG A+ ++ + +T V+ LQ E Sbjct: 2342 LYRKLIISDVHAE-DEDTYTC----DAGDVKTSAQFFVEEQSITIVRGLQ-DVTVMEPAP 2395 Query: 946 VILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 EC+TS KW K + + + QEG G + V Sbjct: 2396 AWFECETSIPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGK 2455 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 +S LVV + R L+ +E +L + V W +D + P + K+ Sbjct: 2456 SRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSE-KF 2514 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 G + +L I D G Y C + EVTV + LQ+ + + Sbjct: 2515 KMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREVTVTGPLQDAEATEEGW 2574 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 A+F EL+ D V W +G + + +++ G++ L + DAG Sbjct: 2575 ASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKV 2634 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 +A L V + F L + T A L E+ D V W K + ++K+ Sbjct: 2635 STSARLEVRVKPVVFLKALDDLSAEERGTLA-LQCEVSDPEAHVVWRKDGVQLGPSDKYD 2693 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 + R L++ + +D YTC + T+ +V V + I + + G Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHV--GSEETRARVRVHDLHVGITKRLKTMEVLEGE 2751 Query: 1304 DVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 + ++ +++ P W V K + + + + L +++ +DAG Sbjct: 2752 SCSFECVLSHESASDP-AMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805 Score = 105 bits (253), Expect = 1e-20 Identities = 83/355 (23%), Positives = 147/355 (41%), Gaps = 38/355 (10%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 P+ AP+F+ +L+ + DG V F+C V G P P + WF+ +++ + + Sbjct: 5117 PSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINE 5176 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH--GSEMTVXXXXX 618 D L+I V P D G + C+A+N+ G +S+ EL V+ +D+ ++ T Sbjct: 5177 DQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYF 5236 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL---------ECRLVAIPEPDIAWLF 669 + EG T + Q V+E D+ + + ++ P P + W Sbjct: 5237 SAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296 Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 G+ + +I + + +H L+I +V + G Y N G A L ++ Sbjct: 5297 DGQPLTASAHIRMTDKKILH----TLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRG 5352 Query: 730 GEKE-------------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 ++ PP+++E V++G S+ S +V G P PT+ W + Sbjct: 5353 PDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERG 5412 Query: 777 AL---------PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 L S HS+ +L + + +G YT A N+ G A SA + V Sbjct: 5413 VLWIGPDTPGYTVASSAQQHSLVLLDVGR-QHQGTYTCIASNAAGQALCSASLHV 5466 Score = 104 bits (250), Expect = 2e-20 Identities = 162/749 (21%), Positives = 289/749 (38%), Gaps = 66/749 (8%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 +EG + +C +V+ + + W G + P E +++ H L I+++ Sbjct: 1911 EEGGEATFQC-VVSPSDVAVVWFRDGALLQPSEKFAISQSGASHS----LTISDLVLEDA 1965 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G TV A EG AS L+++ + P + L+ V + SV L ++ P P Sbjct: 1966 GQITVEA---EG-ASSSAALRVR---EAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPE 2017 Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + W +N P K + ++G H + +L D G + + + + T A +TV Sbjct: 2018 LRWTRNATALAPGKNVEIHAEGARHRL-VLHNVGFADRGFFGCETPDDK----TQAKLTV 2072 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 E + Q + +E+GT + +++ V +W R+ T Sbjct: 2073 E------MRQVRLVRGLQAVEAREQGTATMEVQLSHADVDG-SWTRDGLRFQQGPTCHLA 2125 Query: 883 FDGENIELVITNVDSEIDSG-----------DYKCVASNSAGKSSHGAR--VTIDVEKVT 929 G L ++ + E DSG + V + S + VT + EKVT Sbjct: 2126 VRGPMHTLTLSGLRPE-DSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVT 2184 Query: 930 F----------VKHLQKSYETEEGKTVILECQ---TSHTVSTKWYHNKKEI-----SGMD 971 V+ L+ E GKT+ + Q S T+ + ++ Sbjct: 2185 LECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQS 2244 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 + +GR D G I+ + ++ E+ L VKE +R L+D EK Sbjct: 2245 SASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKIAMEK 2304 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 +LE +++ +A V W + + ++P KY+ G RKL I + DE Y+C Sbjct: 2305 HRGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363 Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN 1150 D +A+ V E I+ LQ+ V + A FE E + +W + +Q Sbjct: 2364 GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGG 2423 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 ++ L +G +L + G VG S+ +A L V + + T L E Sbjct: 2424 NVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPL-EPKTGRE 2482 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 L+ + V WYK + + +EKF + + + L I + D Y C Sbjct: 2483 LQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542 Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 A S+T++ VE E + E + + + + ++ EW +N + Sbjct: 2543 GSAHSSTEVTVEAREVTVTGPLQDAEATEEGWASFSCELSHE---DEEVEWSLNGMPLYN 2599 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + S + +L +K ++ DAGI + Sbjct: 2600 DSFHEISHKGRRHTLVLKSIQRADAGIVR 2628 Score = 98.3 bits (234), Expect = 2e-18 Identities = 119/564 (21%), Positives = 219/564 (38%), Gaps = 39/564 (6%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798 ++ V +G+ LS V G P+P W K+ + V + D + + + K Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G+YT A N G +S ++ V EP A P F R Q++ V+EK + + V + Sbjct: 305 DRGLYTCTASNLVGQTYSSVLVVVREP----AVP--FKKRLQDLEVREKESATFLCEVPQ 358 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P W++ + S +G L + NV ++ D Y C ++ G Sbjct: 359 -PSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSAD-DDAVYIC-------ETPEG 409 Query: 919 ARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREII 976 +R ++ + ++ L + G T + + + V W N++E+ I Sbjct: 410 SRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGPVHWLRNQEEVVAGGRVAIS 469 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK-DVAI 1035 EG DVG + + D +TST V ++ D VK + + ++ Sbjct: 470 AEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSV 529 Query: 1036 LEVEINSETADVVWERDGEIIKPKK-NKYDF---EKRGHIRKLYIRNTSVHDEGEYSCIL 1091 + + DG +++ KK Y + + + + V +EG + + Sbjct: 530 ILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRV 589 Query: 1092 RDESCTAEVTVVELP------PEIITR--LQNQKVNKGNKATFEIELTKGDALVRWFKDG 1143 + + +E P P++ R L+ + +G + TF ++LT A WF DG Sbjct: 590 SALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEVTFSVDLTVASA-GEWFLDG 648 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203 ++ S+ ++ D + L I + G V N ++I + T P Sbjct: 649 QALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKP 708 Query: 1204 -----EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 +L + +A L E+ D+ VTW K + K+ + + +R L++R Sbjct: 709 PAAAAREVLARLHEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDV 768 Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVE 1282 DD Y CV + +L V+ Sbjct: 769 ARDDAGLYECVSRGGRIAYQLSVQ 792 Score = 89.4 bits (212), Expect = 9e-16 Identities = 108/524 (20%), Positives = 208/524 (39%), Gaps = 37/524 (7%) Query: 1139 WFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEE 1193 W KDG + + H+ + LKI C D G Y+C VG + + ++ V E Sbjct: 271 WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE 330 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 P++ F RL + + V A E+P + + W+K+++ + + K+ + + +R L Sbjct: 331 PAVPFKKRLQD-LEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRL 389 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 +R + DD Y C + T E+ + R+ ++ G V+ A Sbjct: 390 TVRNVSADDDAVYICETPEGSRTV---AELAVQGNLLRKLPRKTAVRVGDTAMFCVEL-A 445 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P W+ N + + S + +LTI + D G + +C + Sbjct: 446 VPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF-MAGDC-QTSTQF 503 Query: 1374 NVTILDKP--SPPGKPNILEIDSSSINICWDEPENTGNS-TIIYYVVEYQEIDTTEWI-- 1428 V+ KP PP P + SS+ + W P + TI Y+VE +++ T WI Sbjct: 504 CVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRC 563 Query: 1429 -SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 + + + ++ ++ +++FR A+N S E + + +++P K Sbjct: 564 HEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPL--KA 621 Query: 1488 LKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE---NRXXXXXXXXXXX 1543 ++ + E ++LT G W+ DG+ LK A + YE +R Sbjct: 622 VQAVEGGEVTFSVDLTVASAG------EWFLDGQALK-ASSVYEIHCDRTRHTLTIREVP 674 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGI 1599 + F +G +E+S + ++ P +T + +V +E + A + Sbjct: 675 ASLHGAQLKFVANG-IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSD- 732 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 V W K+G L +Y + V+ ++++ R + Y Sbjct: 733 QAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLY 776 Score = 81.4 bits (192), Expect = 2e-13 Identities = 54/209 (25%), Positives = 96/209 (45%), Gaps = 15/209 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +PKA V G D L C++V P P ++W + + +A + D++ Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYR--- 66 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----GEKEPPQVIEPLKSMIVRQG 749 L I ++ G Y A N GEA + L++ E+ P ++ P S+ VR+G Sbjct: 67 -LTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREG 124 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYT 804 +V G+PRP ++W K+ + + + + G+ ++ I + + +D G Y Sbjct: 125 SEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRI-RAARPRDGGTYE 183 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPP 833 ++AEN G A +A + V+ + A P Sbjct: 184 VRAENPLGAASAAAALVVDSDAADTASRP 212 Score = 81.0 bits (191), Expect = 3e-13 Identities = 90/392 (22%), Positives = 152/392 (38%), Gaps = 27/392 (6%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVAT 567 AP F+ + +GS F C+V G PRP ++W + + ++ ++ + Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 L IR P D GT+ A+N G AS+ L+V++ +D S + Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228 Query: 628 IL--EGIPPT-FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 + EG P + S + V EG L C + P+P+ W K ++V + V Sbjct: 229 AMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWK-KDGQLVTEGRRHVVY 287 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 E + VLKI K+ G YT A N G+ +++ ++ E P + L+ + Sbjct: 288 EDAQENF--VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR--EPAVP-FKKRLQDL 342 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEG 801 VR+ ES + V P W K + A + +G +T+ + D+ Sbjct: 343 EVREKESATFLCE-VPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTV-RNVSADDDA 400 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 VY E EG + T A + V+ + + T G + PV Sbjct: 401 VYI--CETPEG-SRTVAELAVQGN---------LLRKLPRKTAVRVGDTAMFCVELAVPV 448 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVIT 893 + W RN E + + + +G L I+ Sbjct: 449 GPVHWLRNQEEVVAGGRVAISAEGTRHTLTIS 480 Score = 78.6 bits (185), Expect = 2e-12 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 7/195 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P+ + K+ +V G+ LS Q+VGNP P ++W K+ +PV A DGD + +TI Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 L + D G Y +A N+ G A + + V+ + P F+ R I V+E Sbjct: 70 L-DLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDSEIDSGDYKCVAS 909 RV +P P+++W ++ + + + GE L I D G Y+ A Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR-DGGTYEVRAE 187 Query: 910 NSAGKSSHGARVTID 924 N G +S A + +D Sbjct: 188 NPLGAASAAAALVVD 202 Score = 71.7 bits (168), Expect = 2e-10 Identities = 57/248 (22%), Positives = 106/248 (42%), Gaps = 8/248 (3%) Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTV 1102 + VW++DG+++ + +E L I D G Y+C L ++ ++ + V Sbjct: 268 ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327 Query: 1103 VELPP-EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V P RLQ+ +V + ATF E+ + WFK+ + + S + +G ++ Sbjct: 328 VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTER 387 Query: 1162 KLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 +L + + DD Y CE S+ A L V+ N +LP V A VE+ Sbjct: 388 RLTVRNVSADDDAVYICETPEGSRTVAELAVQG---NLLRKLPRKTAVRVGDTAMFCVEL 444 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 V W + + + + + ++ + TL I +C +D + + D +++T+ Sbjct: 445 AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFC 504 Query: 1281 VEVVEFPP 1288 V PP Sbjct: 505 VSAPRKPP 512 Score = 70.5 bits (165), Expect = 5e-10 Identities = 60/207 (28%), Positives = 95/207 (45%), Gaps = 22/207 (10%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT- 786 T E + PQV+E L+ + V G + +V G P P + W K+ +P+ A D Sbjct: 5254 TDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKK 5313 Query: 787 --HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV---EEPTEENAE-------PPL 834 H++ I+ + +D G Y N+ G A +SA + V +EP E+ A PP Sbjct: 5314 ILHTLEIISVTR-EDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPR 5372 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-----IISP-SETITQNFDGENI 888 + RF VK+ +I +V PVP++ W R I P + T + Sbjct: 5373 MLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKS 915 LV+ +V + G Y C+ASN+AG++ Sbjct: 5433 SLVLLDVGRQ-HQGTYTCIASNAAGQA 5458 Score = 68.5 bits (160), Expect = 2e-09 Identities = 50/194 (25%), Positives = 79/194 (40%), Gaps = 11/194 (5%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 PP E L GE+V L+ +V G P+P I+W K+ K V+ P D D Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 IL D G Y A ++ G T I V+ PP F+N+ + E Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ-------VPPRFVNKVRASPFVEGEDA 6125 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + + P P I WY++ +++ T + + +++ S+ D G Y+C Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185 Query: 910 NSAGKSSHGARVTI 923 N G + A + I Sbjct: 6186 NRLGSARASAELRI 6199 Score = 68.1 bits (159), Expect = 2e-09 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATL 568 P FV K+R +G QF C +EG P PQI W++ A++ FQ + + L Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 VIR ED G + C N G A ++ EL +++P+ Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPM 6203 Score = 64.9 bits (151), Expect = 2e-08 Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 9/188 (4%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRXXXX 1536 P E+ L + T E E ++L C G P+P ++WY+DGK ++ + Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C A + G T + +Q P N+ G++ T I Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQFTCTI 6131 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTIEASNTAGTS 1654 EG P P++ WYK+G L ++ ++ ++ V+ I+ + Y E N G++ Sbjct: 6132 EGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSA 6191 Query: 1655 SVEVTLKV 1662 L++ Sbjct: 6192 RASAELRI 6199 Score = 61.3 bits (142), Expect = 3e-07 Identities = 57/221 (25%), Positives = 89/221 (40%), Gaps = 26/221 (11%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S AP F+ + + G CQ+ G P PQ++W + + F++ D D + Sbjct: 7 SGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LY 65 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 L I ++ D+G + C A+NA G A + L V+A + +E Sbjct: 66 RLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--CAEQA-------------- 109 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 P F +P + V EGS+ CR+ P P ++W G + + V +E Sbjct: 110 -------PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEE 162 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 S L+I + GTY V A N G AS L + Sbjct: 163 LGE--ASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201 Score = 60.1 bits (139), Expect = 7e-07 Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 7/156 (4%) Query: 1597 EGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 E +P E WY NG ++ +D ++ +T + ++ + H+ + T + ++ Sbjct: 4457 EAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASAR 4516 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 + V L + D P E V+ R S +VT+ W P+ DGG L Y +E E +W Sbjct: 4517 LTV-LGLPDPPEDAE--VVAR--SSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRL 4571 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 ++ E + L Y FRV A PVG E Sbjct: 4572 CHELVPGPEC-VVDGLAPGETYRFRVAAVGPVGAGE 4606 Score = 58.8 bits (136), Expect = 2e-06 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T QFE +EG P+P +TW++ + + S + +LV+R V +DAG +TC Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQ-QEGTTYSLVLRHVASKDAGVYTC 6429 Query: 584 VAKNAAGFASSTTELIV 600 +A+N G EL+V Sbjct: 6430 LAQNTGGQVLCKAELLV 6446 Score = 58.4 bits (135), Expect = 2e-06 Identities = 52/221 (23%), Positives = 101/221 (45%), Gaps = 11/221 (4%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS--PSETITQNFDGENIE 889 PP F + T + T+KL RVT P P I+WY++ + + P + ++ DG + Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDG-SCA 6071 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 L++ ++ +DSG Y C A+++AG S ++ + V FV ++ S EG+ Sbjct: 6072 LILDSLTG-VDSGQYMCFAASAAGNCSTLGKILVQVPP-RFVNKVRAS-PFVEGEDAQFT 6128 Query: 950 C--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX--XXXXXXXXXXXDVGVIKCIVKDQE 1005 C + + +WY + ++ + + + E R D+G+ +C + ++ Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 S + I + + Q+ +E+ VA +E + E AD Sbjct: 6189 GSARASAELRIQSPMLQAQEQCHREQLVAAVE-DTTLERAD 6228 Score = 58.4 bits (135), Expect = 2e-06 Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 8/134 (5%) Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 T T + A PP +++ + GT + A + +P PS+TWY+++ + Sbjct: 6340 TQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVD 6399 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVEKV 928 S ++Q +G LV+ +V S+ D+G Y C+A N+ G+ A + + D EK Sbjct: 6400 STRLSQQQEGTTYSLVLRHVASK-DAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQ 6458 Query: 929 TFVKHLQKSYETEE 942 + + L YE +E Sbjct: 6459 SHRRKLHSFYEVKE 6472 Score = 57.2 bits (132), Expect = 5e-06 Identities = 27/94 (28%), Positives = 48/94 (51%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F E+L G TV+ C+V G P+P I+W++ ++ + D D L+ Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + D+G + C A +AAG S+ +++V+ P Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107 Score = 55.2 bits (127), Expect = 2e-05 Identities = 43/197 (21%), Positives = 86/197 (43%), Gaps = 11/197 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F ++ + G + L CR+ P+P I+W G+ + D + + IE D C Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HILIE-DPDGSC 6070 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +++ + ++ G Y A + G S + ++ PP+ + +++ +GE Sbjct: 6071 ALI-LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV----PPRFVNKVRASPFVEGEDA 6125 Query: 753 ILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH-SITILKPKKVKDEGVYTLKAE 808 + + G P P I W K+ + T S+ + + +++ +D G+Y + Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELV 6185 Query: 809 NSEGIAETSAVITVEEP 825 N G A SA + ++ P Sbjct: 6186 NRLGSARASAELRIQSP 6202 Score = 54.4 bits (125), Expect = 3e-05 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 3/119 (2%) Query: 815 ETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 ET A + EP + P+F+ Q V++ + VT P+PS+ W+++ + Sbjct: 5105 ETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK 5164 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 ++ + N D + +I D G Y+C+A NS G SS A + +D+ + Sbjct: 5165 LLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDY 5223 Score = 53.2 bits (122), Expect = 8e-05 Identities = 69/334 (20%), Positives = 125/334 (37%), Gaps = 24/334 (7%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 +Q P+F G ++ EC V + W + + + + D Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 +L+I + DAG +TC N G + + ++V GSE Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVS------GSESEAESSSGGELDDA 5006 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLEC-RLVAIPEPDIAW-LFKGEE---IVPDEN 679 + F K A+ DE ++ L A PE W ++ +E + E Sbjct: 5007 FRRAARRLHRLFRTKSPAEVSDE--ELFLSADEGPAEPEEPADWQTYREDEHFICIRFEA 5064 Query: 680 ISVA---IESDMHMYCSVLKITNVKKFQEGTYTV-VAVNREGEASL--PIVLKIKTGEKE 733 ++ A + M+ ++ +K ++G V + +++E A + P L Sbjct: 5065 LTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISKETPAPVVPPEPLPSLLTSDA 5124 Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSI 789 P + L++ V+ G V V G P P++ W K+ K ++ + + H + Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 I+ D GVY AENS G++ T A + V+ Sbjct: 5185 -IITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217 Score = 50.4 bits (115), Expect = 5e-04 Identities = 28/87 (32%), Positives = 39/87 (44%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F+ +L + G +V CQV P Q TW + A ++ S + N L Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASST 595 I V ED G +TC NA G ++T Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548 Score = 49.6 bits (113), Expect = 0.001 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 9/138 (6%) Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSD 783 I T PP + ++ + + G + A + G+P+P++TW K++ + L + + Sbjct: 6349 IDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQE 6408 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV----EEPTEENAEPPLFINRF 839 G T+S+ +L+ KD GVYT A+N+ G A + V EP E ++ F Sbjct: 6409 GTTYSL-VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSHRRKLHSF 6467 Query: 840 QEITVK-EKGTIKLVARV 856 E+ + +G V RV Sbjct: 6468 YEVKEEIGRGVFGFVKRV 6485 Score = 48.8 bits (111), Expect = 0.002 Identities = 38/118 (32%), Positives = 53/118 (44%), Gaps = 6/118 (5%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSVHE 1924 P P + V +S +VTL W P S+GG + Y +E K W V G E Sbjct: 4523 PDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGP--E 4580 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL-EKHATVPSPPTAPLEIRMVGS 1980 ++ + + FR++A VG P Q+VRL E VP P+AP E R V + Sbjct: 4581 CVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAP-ESRQVAA 4637 Score = 46.8 bits (106), Expect = 0.007 Identities = 35/155 (22%), Positives = 57/155 (36%), Gaps = 4/155 (2%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVV 1284 ++WYK ++ LI D LI+ T D +Y C A + L +V Sbjct: 6045 ISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILV 6104 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA- 1343 + PP+ V+ R G D + P P W + ++ + + +S Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164 Query: 1344 -SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 L I+ D G+Y+ L N G A + I Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRI 6199 Score = 46.4 bits (105), Expect = 0.009 Identities = 52/215 (24%), Positives = 81/215 (37%), Gaps = 16/215 (7%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP+ L + G +T ++ W+KDG +Q H L D Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072 Query: 1165 IYDCDLD-DAGEYSC----EVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 I D D+G+Y C GN S IL P +R F+ DA T Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFV---EGEDAQFTC 6129 Query: 1219 EIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAKS 1275 I + WYK +++ KF +S+ + L+IR +++D Y C L++ Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189 Query: 1276 TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTL 1307 + + E+ P + E RE + D TL Sbjct: 6190 SARASAELRIQSPMLQAQEQCHREQLVAAVEDTTL 6224 Score = 46.0 bits (104), Expect = 0.011 Identities = 42/180 (23%), Positives = 75/180 (41%), Gaps = 15/180 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+ + + F V A L +I + T V WE+D + + ++ + G + +L Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLAQDGDLYRLT 68 Query: 1076 IRNTSVHDEGEYSCILRDE----------SCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125 I + ++ D G+Y C R+ AE E P + R + +V +G++AT Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128 Query: 1126 FEIELTKGD-ALVRWFKDGSEIQFSNHIQLTID--GKKQKLKIYDCDLDDAGEYSCEVGN 1182 F + V W KDG + + ++ ++ G+ L+I D G Y N Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAEN 188 Score = 45.6 bits (103), Expect = 0.015 Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 15/201 (7%) Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L P+ +V DA L+ +I + T V+W K + + +F L D L I Sbjct: 13 LTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDL 72 Query: 1259 TEDDQCEYTC----VLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 D +Y C + +A + L+V+ E P + R++ GS+ T Sbjct: 73 ALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCR 132 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSID--SKSASLTIKKVENTDAGIYKLRLENNCGH 1368 P+P W + + + + + ++ ++++L I+ D G Y++R EN G Sbjct: 133 VGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGA 192 Query: 1369 ADVEMNVTI----LDKPSPPG 1385 A + + D S PG Sbjct: 193 ASAAAALVVDSDAADTASRPG 213 Score = 45.6 bits (103), Expect = 0.015 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 + L PK + +V C P+ + W++ + PS+ F+M + +A L I Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQ-MAELRI 2527 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + P DAG + C AG A S+TE+ VEA Sbjct: 2528 LRLMPADAGVYRC----QAGSAHSSTEVTVEA 2555 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/90 (30%), Positives = 41/90 (45%) Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 PE V A D L +E+ E +V W+K I+ +F ++S +++ L+I+ T +D Sbjct: 4630 PESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAED 4689 Query: 1263 QCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292 Q EY C L V P VD Sbjct: 4690 QGEYHCGLAQGSICPAAATFQVALSPASVD 4719 Score = 44.0 bits (99), Expect = 0.046 Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNK-ATFEIELTKGDALVR--WFKDGSEIQF 1148 R++ T T P+++ L++ +V G + A F++++ KG R WFKDG + Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKV-KGYPAPRLYWFKDGQPLTA 5303 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 S HI++T L+I +D+G+Y+ + N+ Sbjct: 5304 SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338 Score = 43.6 bits (98), Expect = 0.061 Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 4/79 (5%) Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 +DV+ LE+E+ +E +V+W + E I+P +++ +G + L I+ + D+GEY C Sbjct: 4639 EDVS-LELEVVAEAGEVIWHKGMERIQP-GGRFEVVSQGRQQMLVIKGFTAEDQGEYHCG 4696 Query: 1091 LRDES-CTAEVTV-VELPP 1107 L S C A T V L P Sbjct: 4697 LAQGSICPAAATFQVALSP 4715 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%) Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTL 2024 +P PP E+ S+ V SW P DGG L GY + +++ W ++ V Sbjct: 4522 LPDPPE-DAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHEL-VPGP 4579 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 + + L+ TY R+ A +G EP+ Sbjct: 4580 ECVVDGLAPGETYRFRVAAVGPVGAGEPV 4608 Score = 42.7 bits (96), Expect = 0.11 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 4/80 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK-KQKL 1163 P +T LQNQ+V G +F+ +T G + VRWFKDG ++ +H + D + +L Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVT-GQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184 Query: 1164 KIYDCDLDDAGEYSCEVGNS 1183 I D G Y C NS Sbjct: 5185 IITAVVPADMGVYRCLAENS 5204 Score = 42.3 bits (95), Expect = 0.14 Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 1/94 (1%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P F+ R + V L ++ NP P ++W ++ + ++ DG+ L I Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ DSG Y C A N+ G++ + +D E Sbjct: 70 LDLALG-DSGQYVCRARNAIGEAFAAVGLQVDAE 102 Score = 41.9 bits (94), Expect = 0.19 Identities = 41/187 (21%), Positives = 67/187 (35%), Gaps = 15/187 (8%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXX 1544 K +D L+C G P P+V+W +D + + A + Sbjct: 17 KAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGD 76 Query: 1545 XXXYKCIAFNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y C A N GE + + + +Q P + I+ + G E + Sbjct: 77 SGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVRE--GSEATFRCRVG 134 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 G P P V W K+G +L + +E + S +RI+ + Y + A N G +S Sbjct: 135 GSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAAS 194 Query: 1656 VEVTLKV 1662 L V Sbjct: 195 AAAALVV 201 Score = 41.9 bits (94), Expect = 0.19 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 2/102 (1%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 IL +PP F K +A EG D C + P P I W G + E Sbjct: 6102 ILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPR 6161 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 + VL I K G Y VNR G A L+I++ Sbjct: 6162 SGLL--VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201 Score = 41.9 bits (94), Expect = 0.19 Identities = 38/164 (23%), Positives = 62/164 (37%), Gaps = 7/164 (4%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYT 1644 +G + + P + W K+G LE+ I+ T + ++ I + YT Sbjct: 7476 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 7535 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 SN GT + L+ ++PS P I E+ + V + WKP G + I Sbjct: 7536 CSVSNALGTVTTTGVLRKAERPSSSPCPDI-GEVYADGVLLVWKPVESYGPVTY----IV 7590 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 + + W +A D Y KL+ Y FR + G Sbjct: 7591 QCSLEGGSWTTLASDIFDC-CYLTSKLSRGGTYTFRTACVSKAG 7633 Score = 41.5 bits (93), Expect = 0.25 Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 2/100 (2%) Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P + ++ ED++ + G A+IEG P P V WYK+ +L + + + T + Sbjct: 6357 PSMQVTIEDVQAQ--TGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSL 6414 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 ++ + + YT A NT G + L V ++P+ Sbjct: 6415 VLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPD 6454 Score = 40.7 bits (91), Expect = 0.43 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT-- 1653 ++G P P + W+K+G L +T K+ + I + R S +Y SN G Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343 Query: 1654 SSVEVTLKVYDKP-SKPEGPV 1673 SS + ++ D+P KP V Sbjct: 5344 SSARLLVRGPDEPEEKPASDV 5364 Score = 40.3 bits (90), Expect = 0.57 Identities = 21/103 (20%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + + ++ T Y+ I + P+++ ++++ + + I G PQP VTWY+D Sbjct: 6336 VRETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSV 6395 Query: 1521 KLKTAKATYENRXXXXXX----XXXXXXXXXYKCIAFNDHGEV 1559 +L + + + Y C+A N G+V Sbjct: 6396 QLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQV 6438 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P +TR + V+ G AT ++ V W KD + +L DG +L I Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69 Query: 1166 YDCDLDDAGEYSCEVGNS 1183 D L D+G+Y C N+ Sbjct: 70 LDLALGDSGQYVCRARNA 87 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 1582 QKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKELKRS 1638 Q +V D + V+ V+ G P P V W+K+G LE D Y I ++ + I + + Sbjct: 5133 QNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPA 5192 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV 1662 Y A N+ G SS + L+V Sbjct: 5193 DMGVYRCLAENSMGVSSTKAELRV 5216 Score = 39.9 bits (89), Expect = 0.75 Identities = 38/170 (22%), Positives = 65/170 (38%), Gaps = 6/170 (3%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKL 1360 G VTL A P W + ++ S K+ L TI V D G+Y Sbjct: 7477 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 7536 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + N G + ++PS P+I E+ + + + W E+ G T Y+V+ Sbjct: 7537 SVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVT---YIVQC- 7592 Query: 1421 EIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ W ++ +I L +Y FR V++ + S +E Sbjct: 7593 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSE 7642 Score = 39.1 bits (87), Expect = 1.3 Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 2/73 (2%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 +F++ L + T+ +C+V P + W + + PS + + LV+ Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTA-GTRGLVV 2705 Query: 571 REVFPEDAGTFTC 583 +V PEDAG +TC Sbjct: 2706 HDVSPEDAGLYTC 2718 Score = 39.1 bits (87), Expect = 1.3 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 5/104 (4%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSIT 790 P + L V G+SV L+ QV P TW K+ P+ + L + + + +T Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 IL +D GVYT N+ G T+ V+ E + P + Sbjct: 7523 IL-VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI 7565 Score = 38.7 bits (86), Expect = 1.7 Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 509 API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 AP+ F+ +L+ + +G T C++ + W + + + P +QM D A Sbjct: 3977 APVRFLRELQHQEVDEGGTAHLCCELSR-AGASVEWRKGSLQLFPCAKYQMV-QDGAAAE 4034 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593 L++R V EDAG +TC + AS Sbjct: 4035 LLVRGVEQEDAGDYTCDTGHTQSMAS 4060 Score = 38.3 bits (85), Expect = 2.3 Identities = 38/182 (20%), Positives = 71/182 (39%), Gaps = 14/182 (7%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYEN---RXXXXXXXXXXX 1543 + T + L+C G P+P+ W +DG+ + + YE+ Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP- 1602 Y C A N G+ +S +V + ++P + Q +V ++ T + E +P P Sbjct: 305 DRGLYTCTASNLVGQTYSSVLV-VVREPAVPFKKR--LQDLEVREKESATFLCE-VPQPS 360 Query: 1603 -EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY---TIEASNTAGTSSVEV 1658 E W+K +L +Y I + + ++ + + Y T E S T +V+ Sbjct: 361 TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQG 420 Query: 1659 TL 1660 L Sbjct: 421 NL 422 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 1114 QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 ++++V G + E+E+ V W K IQ ++ G++Q L I +D Sbjct: 4631 ESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQ 4690 Query: 1174 GEYSCEVG-NSKCTAILTVE 1192 GEY C + S C A T + Sbjct: 4691 GEYHCGLAQGSICPAAATFQ 4710 Score = 37.5 bits (83), Expect = 4.0 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 2/79 (2%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 ++ + G P PE +W K+G + + + + ++ V++I K+S YT ASN Sbjct: 257 LSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNL 316 Query: 1651 AGTSSVEVTLKVYDKPSKP 1669 G + V L V +P+ P Sbjct: 317 VGQTYSSV-LVVVREPAVP 334 Score = 37.5 bits (83), Expect = 4.0 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 5/93 (5%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F+ L +G F+C V + WFR A+++PS+ F + + +L I Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGAS-HSLTIS 1958 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 ++ EDAG T A G +SS + EAP+ Sbjct: 1959 DLVLEDAGQITV---EAEGASSSAALRVREAPV 1988 Score = 37.5 bits (83), Expect = 4.0 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V+F C+V + W Q ++ ++ ++ D + TL ++ V PEDAGT + Sbjct: 4176 VEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLG 4235 Query: 587 NAAGFASSTT---ELIVEAPLSD 606 N A A T E+ + PL D Sbjct: 4236 NHASSAQLTVRAPEVTILEPLQD 4258 Score = 37.1 bits (82), Expect = 5.3 Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 2/144 (1%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKK-QKLK 1164 P + L ++ V G T +++ A W KDG+ ++ S+ + ++ K Q L Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I +D G Y+C V N+ T T P + D L V P E+ Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVES 7582 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDV 1248 Y + +E TL SD+ Sbjct: 7583 YGPVTYIVQCSLEGGSWTTLASDI 7606 Score = 36.3 bits (80), Expect = 9.2 Identities = 20/81 (24%), Positives = 35/81 (43%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P F+ + TV ++ L +V+ P TW ++ + S + + +N +L+ Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522 Query: 893 TNVDSEIDSGDYKCVASNSAG 913 V D G Y C SN+ G Sbjct: 7523 ILVVVAEDLGVYTCSVSNALG 7543 >UniRef50_Q17HV8 Cluster: Myomesin; n=3; Culicidae|Rep: Myomesin - Aedes aegypti (Yellowfever mosquito) Length = 924 Score = 190 bits (462), Expect = 5e-46 Identities = 191/746 (25%), Positives = 313/746 (41%), Gaps = 81/746 (10%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII--KPS 553 PV E + +AP F++K + DG + FECQ++ P+PQI W + +I P Sbjct: 104 PVDEPVEKQIDGLAPTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPR 163 Query: 554 QDFQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612 F++ D ATL + V ED+G + AKN G +S+T L ++ E+ Sbjct: 164 HKFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDS------EEVP 217 Query: 613 VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672 V +G P F+++P + D+G +I+ ECR + P+P W E Sbjct: 218 VPA--------------DGFKPAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVYHE 263 Query: 673 --EIVPDENISVAIESDM-HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL---- 725 E+ S E D H Y I +VK+ G Y VVA N+ G++S I L Sbjct: 264 KNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQLDRGVYNVVAKNKHGDSSAIINLNFDS 323 Query: 726 --KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KA 777 KI E +PP+ P K I ++GE + + + P ITW + + K Sbjct: 324 SAKIVNPEGKPPRF--PQKPTISQKGEVLSMECILEALPVADITWFHGTETITDGERFKI 381 Query: 778 LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE--PPL 834 L DT+ +T+ + D G+Y A N G E++A IT+ EN P Sbjct: 382 LRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFG--ESNAHITLNFKANENDRGFAPS 439 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI---TQNFDGENIELV 891 F+ + + I K I + R P P++ W R + + S + + D + EL Sbjct: 440 FVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELT 499 Query: 892 ITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK---HLQKSY--ETEEGKT 945 + D S D G Y CV SN G+SS + I+ E+ + ++K + + GK Sbjct: 500 LNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKL 559 Query: 946 VILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX----XXXDVGVIKC 999 V +EC +T W + I +I D G KC Sbjct: 560 VRMECKVKTDLKPDITWTREGRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKC 619 Query: 1000 IVKD--QETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEI 1055 +K+ E + L++ E +P K + +K A +E + S + +W ++ + Sbjct: 620 NIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKRTASIECAVASRFKPECIWMKETTV 679 Query: 1056 IKPKKN---KYDFEKRGHIR-KLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL------ 1105 IK K + ++G KL I S D G Y + +++ A V+E+ Sbjct: 680 IKETHRHMIKIEETRQGEFSVKLNITELSEADFGAYKLVAKNDKGQATSQVIEIKDIVFE 739 Query: 1106 -PPE----IITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTIDG 1158 PP I +L++ +V++G T + L D V W K+ + ++ S + G Sbjct: 740 KPPPTKPIIDPKLKDVEVDEGGNLTLAVGLVHPDRHFKVYWMKNKTILKTSETVIQEFSG 799 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSK 1184 + KL + +C ++DAG Y + N + Sbjct: 800 RMAKLTVKNCTVEDAGTYKVSISNEQ 825 Score = 174 bits (423), Expect = 3e-41 Identities = 201/882 (22%), Positives = 377/882 (42%), Gaps = 112/882 (12%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ----DFQMYY 560 + AP F +K + + DG+ + FECQ+ P+P I W+R ++ + Q + Sbjct: 3 DHDFAPSFTQKPQLRQEDDGNRLVFECQLIAKPKPAIEWYRSEELLSQNARTKFKIQSFG 62 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620 ++ L + +V DAG + AKN G S++ L +P+ + + Sbjct: 63 ENKYFVVLELDDVIDTDAGLYKVKAKNRMGEVSASINLNF-SPVDEPVEKQ--------- 112 Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 ++G+ PTF KKP Q ++G ++ EC++ A P+P I W + I Sbjct: 113 --------IDGLAPTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRH 164 Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIE 739 +++D +Y + L++ NV G Y V A N GE+S I L + E P + Sbjct: 165 KFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDSEEVPVPADGFK 224 Query: 740 P--LKSMIVRQ---GESVILSAQVVGNPRPTITWC----KNNKPVKA-LPTKSDGD-THS 788 P + + RQ G++++ + +G+P+PT TW KN + ++++ D H Sbjct: 225 PAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHC 284 Query: 789 ITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRF-QEIT 843 I ++ K D GVY + A+N G ++SA+I + + + + P RF Q+ T Sbjct: 285 YLIRFTIRDVKQLDRGVYNVVAKNKHG--DSSAIINLNFDSSAKIVNPEGKPPRFPQKPT 342 Query: 844 VKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEI- 899 + +KG + + + PV ITW+ E I+ E I + + L+ + Sbjct: 343 ISQKGEVLSMECILEALPVADITWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTA 402 Query: 900 -DSGDYKCVASNSAGKSSHGARVTIDVE--------KVTFVKHLQKSYETEEGKTVILE- 949 D G Y+C A N G+S+ A +T++ + +FV+ K + G + ++ Sbjct: 403 NDGGIYRCHAFNPFGESN--AHITLNFKANENDRGFAPSFVEK-PKIIPNKLGTLITMKC 459 Query: 950 -CQTSHTVSTKWYHNKKEIS-----GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 C++ + KW K+E+ ++ + + ++ D G C++ + Sbjct: 460 RCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISN 519 Query: 1004 Q--ETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERD 1052 + E+S L + + P F+ K + + +E ++ ++ D+ W R+ Sbjct: 520 EFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKLVRMECKVKTDLKPDITWTRE 579 Query: 1053 GEIIKPK---KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELP 1106 G II+ K EK + L +++ D G Y C +++ E + +E+ Sbjct: 580 GRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIV 639 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQ-- 1161 P + + + + V K T IE W K+ + I+ ++ + I+ +Q Sbjct: 640 P--VIKEKPKLVTNVKKRTASIECAVASRFKPECIWMKETTVIKETHRHMIKIEETRQGE 697 Query: 1162 ---KLKIYDCDLDDAGEYSCEVGNSKCTAI--------LTVEEPSINFTLRLPEFILVPA 1210 KL I + D G Y N K A + E+P + P+ V Sbjct: 698 FSVKLNITELSEADFGAYKLVAKNDKGQATSQVIEIKDIVFEKPPPTKPIIDPKLKDVEV 757 Query: 1211 NTDAYLTVEI----PDETLDVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQC 1264 + LT+ + PD V W K K++++ +E T+I + R L ++ CT +D Sbjct: 758 DEGGNLTLAVGLVHPDRHFKVYWMKNKTILKTSE--TVIQEFSGRMAKLTVKNCTVEDAG 815 Query: 1265 EYTCVLLDAKST--TKLKVEVVEFP--PKIVDYEREYRIKRG 1302 Y + + + + ++ KVE + P PKI++ +E K+G Sbjct: 816 TYKVSISNEQQSDESEAKVEEAKKPEVPKIME-TKEPEPKKG 856 Score = 148 bits (358), Expect = 2e-33 Identities = 185/841 (21%), Positives = 346/841 (41%), Gaps = 95/841 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES-DMHMYC 692 P+F++KP+ + D+G+ ++ EC+L+A P+P I W E + + I+S + Y Sbjct: 8 PSFTQKPQLRQEDDGNRLVFECQLIAKPKPAIEWYRSEELLSQNARTKFKIQSFGENKYF 67 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---- 748 VL++ +V G Y V A NR GE S I L ++ + I+ L +++ Sbjct: 68 VVLELDDVIDTDAGLYKVKAKNRMGEVSASINLNFSPVDEPVEKQIDGLAPTFIKKPSIQ 127 Query: 749 ----GESVILSAQVVGNPRPTITWCKNNKPVKALP-----TKSDGDTHSITI-LKPKKVK 798 G+ +I Q+ +P+P I W N+K + P ++DG + T+ + + Sbjct: 128 QENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFATLEVDNVTFE 187 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEP-----PLFINRFQEITVKEKGTIKLV 853 D G Y + A+N G E+SA I++ +EE P P F R + I Sbjct: 188 DSGKYKVTAKNELG--ESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSDDGKNIVFE 245 Query: 854 ARVTRNPVPSITW---YRNNEIISPSETITQNFDGEN----IELVITNVDSEIDSGDYKC 906 R +P P+ TW + NE+ ++ + +N I I +V ++D G Y Sbjct: 246 CRCIGDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDV-KQLDRGVYNV 304 Query: 907 VASNSAGKSSHGARVTIDVE-KVTFV-----KHLQKSYETEEGKTVILEC--QTSHTVST 958 VA N G SS + D K+ + QK +++G+ + +EC + Sbjct: 305 VAKNKHGDSSAIINLNFDSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECILEALPVADI 364 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXX-----XXXDVGVIKCIVKDQ--ETSTMLV 1011 W+H + I+ + +I+++ D G+ +C + E++ + Sbjct: 365 TWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFGESNAHIT 424 Query: 1012 V--------KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNK 1062 + + P F+ K + K + ++ S+ V W R + +K NK Sbjct: 425 LNFKANENDRGFAPSFVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVK-SSNK 483 Query: 1063 YDFEKRGHIRKLY-----IRNTSVHDEGEYSCILRDE----SCTAEVTV------VELPP 1107 E + Y I++ S D G YSC++ +E S T + + + P Sbjct: 484 VALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAP 543 Query: 1108 EIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ----K 1162 + + ++ G E ++ T + W ++G IQ + +++T+ +K Sbjct: 544 IFVEKPHIVSLDNGKLVRMECKVKTDLKPDITWTREGRIIQETTKLKITMTAEKDVYHIS 603 Query: 1163 LKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 L + D +D+G Y C + N + A L + + P+ + A + + Sbjct: 604 LVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKRTASIECAV 663 Query: 1221 PDETL-DVTWYKKKSVIEDTEKFTL-ISDVKKRTLIIR-KCTEDDQCEYTCVLLDAKS-- 1275 + W K+ +VI++T + + I + ++ ++ TE + ++ L AK+ Sbjct: 664 ASRFKPECIWMKETTVIKETHRHMIKIEETRQGEFSVKLNITELSEADFGAYKLVAKNDK 723 Query: 1276 ------TTKLKVEVVEFPPK---IVDYE-REYRIKRGSDVTLLVDYQAFPQPNDE--WIV 1323 ++K V E PP I+D + ++ + G ++TL V P + + W+ Sbjct: 724 GQATSQVIEIKDIVFEKPPPTKPIIDPKLKDVEVDEGGNLTLAVGL-VHPDRHFKVYWMK 782 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 N I+K + + A LT+K DAG YK+ + N + E V KP Sbjct: 783 NKTILKTSETVIQEFSGRMAKLTVKNCTVEDAGTYKVSISNEQQSDESEAKVEEAKKPEV 842 Query: 1384 P 1384 P Sbjct: 843 P 843 Score = 57.6 bits (133), Expect = 4e-06 Identities = 150/736 (20%), Positives = 272/736 (36%), Gaps = 84/736 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII-KPKKNKYDFEKRG--HIR 1072 P FI+K + + I E +I ++ + W + ++I ++K+ + G + Sbjct: 118 PTFIKKPSIQQENDGKRLIFECQIQADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFA 177 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVV------ELP-------PEIITRLQNQKVN 1119 L + N + D G+Y ++E + T+ E+P P R ++ + Sbjct: 178 TLEVDNVTFEDSGKYKVTAKNELGESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSD 237 Query: 1120 KGNKATFEIELTKGDA--LVRW--FKDGSEIQFSNHIQLTIDGKKQ-----KLKIYDCDL 1170 G FE GD W + + +E+Q + + + I D Sbjct: 238 DGKNIVFECRCI-GDPKPTYTWQVYHEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQ 296 Query: 1171 DDAGEYSCEVGNSK--CTAILTVEEPS----INFTLRLPEFILVP--ANTDAYLTVEIPD 1222 D G Y+ N +AI+ + S +N + P F P + L++E Sbjct: 297 LDRGVYNVVAKNKHGDSSAIINLNFDSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECIL 356 Query: 1223 ETL---DVTWYKKKSVIEDTEKFTLI-----SDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272 E L D+TW+ I D E+F ++ +D TL I + T +D Y C + Sbjct: 357 EALPVADITWFHGTETITDGERFKILRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPF 416 Query: 1273 ----AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 A T K + F P V+ + K G+ +T+ ++ P+P +W+ + Sbjct: 417 GESNAHITLNFKANENDRGFAPSFVEKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQ 476 Query: 1327 IIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI---- 1377 +K + D+ +L IK D G Y + N G + +N+ I Sbjct: 477 EVKSSNKVALEVKTVDEDTYELTLNIKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQ 536 Query: 1378 ---LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---- 1430 + P KP+I+ +D+ + + + T I + E + I T + + Sbjct: 537 ESTKNAPIFVEKPHIVSLDNGKL-VRMECKVKTDLKPDITWTREGRIIQETTKLKITMTA 595 Query: 1431 -KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS--ETTEYYKVIKETKIQSPTVEKP 1487 K++ +++ +T S ++ N + +A+ E VIKE V+K Sbjct: 596 EKDVYHISLVLKDPQTEDSGTYKCNIKNILGELNANLILNIEIVPVIKEKPKLVTNVKKR 655 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547 +I + CI+ +R K++ + E Sbjct: 656 TASIECAVASRFKPECIWMKETTVIKETHRHMIKIEETRQG-EFSVKLNITELSEADFGA 714 Query: 1548 YKCIAFNDHGEVETSCVVGIQ----QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 YK +A ND G+ TS V+ I+ +KP T D K K DE + G+ P+ Sbjct: 715 YKLVAKNDKGQA-TSQVIEIKDIVFEKPPPTKPIIDPKLKDVEVDEGGNLTLAVGLVHPD 773 Query: 1604 ----VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 V W KN L+ + + + + +K + Y + SN + E Sbjct: 774 RHFKVYWMKNKTILKTSETVIQEFSGRMAKLTVKNCTVEDAGTYKVSISNEQQSDESEAK 833 Query: 1660 LKVYDKPSKPEGPVIM 1675 + ++ KPE P IM Sbjct: 834 V---EEAKKPEVPKIM 846 Score = 57.2 bits (132), Expect = 5e-06 Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 3/129 (2%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D +Y+ + + E L + + E APIFVEK +G V+ EC+V+ Sbjct: 509 DGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEKPHIVSLDNGKLVRMECKVKT 568 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYY---DDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 +P ITW R+ II+ + ++ D +LV+++ ED+GT+ C KN G Sbjct: 569 DLKPDITWTREGRIIQETTKLKITMTAEKDVYHISLVLKDPQTEDSGTYKCNIKNILGEL 628 Query: 593 SSTTELIVE 601 ++ L +E Sbjct: 629 NANLILNIE 637 Score = 49.6 bits (113), Expect = 0.001 Identities = 81/407 (19%), Positives = 142/407 (34%), Gaps = 41/407 (10%) Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS----ASLTIKKVENTDAGIYKLRLENNCG 1367 QA P+P W NSK+I K + + A+L + V D+G YK+ +N G Sbjct: 142 QADPKPQIRWSHNSKVIDNTPRHKFKVQNDGKLYFATLEVDNVTFEDSGKYKVTAKNELG 201 Query: 1368 H--ADVEMNVTILDKPSPPG--KPNILEI-------DSSSINI---CWDEPENTGNSTII 1413 A + +N + P P KP E D +I C +P+ T + Sbjct: 202 ESSATISLNFDSEEVPVPADGFKPAFTERPVTRQSDDGKNIVFECRCIGDPKPTYTWQVY 261 Query: 1414 YYVVEYQ---EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + E Q + + + +I+++K + A N+ S A + Sbjct: 262 HEKNEMQMGGRFSSETEEDQNHCYLIRFTIRDVKQLDRGVYNVVAKNKHGDSSAIINLNF 321 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR------DGKKLKT 1524 K + P K ++ E + + CI +P +TW+ DG++ K Sbjct: 322 DSSAKIVNPEGKPPRFPQKPTISQKGEVLSMECILEALPVADITWFHGTETITDGERFKI 381 Query: 1525 AKATYENRX---XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 + N Y+C AFN GE + + Sbjct: 382 LRKAISNDTYLLTLQISQPTANDGGIYRCHAFNPFGESNAHITLNFKANENDRGFAPSFV 441 Query: 1582 QKHKVGDEWLVTAV-----IEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKT--SVIR 1631 +K K+ L T + P P V W + ++++ + + T E T + Sbjct: 442 EKPKIIPNKLGTLITMKCRCRSKPKPTVKWMRKKQEVKSSNKVALEVKTVDEDTYELTLN 501 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKV-YDKPSKPEGPVIMRE 1677 IK+ Y+ SN G SS + L + ++ S P+ + + Sbjct: 502 IKDPSAEDGGSYSCVISNEFGESSATLNLNIESEQESTKNAPIFVEK 548 >UniRef50_UPI0000F2B6E2 Cluster: PREDICTED: hypothetical protein; n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical protein - Monodelphis domestica Length = 3881 Score = 186 bits (454), Expect = 4e-45 Identities = 244/1098 (22%), Positives = 430/1098 (39%), Gaps = 114/1098 (10%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+ S G + +LEC+ +P P + W G E++ ++ + Sbjct: 609 PPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRGGLEMILAPEVA---------HT 659 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L+I V++ G Y AVN G AS I L++ P+++E ++M+V G + Sbjct: 660 GTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYA----PRLVESSRNMVVEMGRNA 715 Query: 753 ILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH---SITILKPKKVKDEGVYTLKAE 808 IL+ + G P P ITW + + KPV A P + + + L+ +D+ +Y +A Sbjct: 716 ILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAH 775 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV-TRNPVPSITWY 867 N+ G A+ +TV EPP + + V E L V P P W Sbjct: 776 NTFGKAQAEVQLTV-----IGHEPPQIASSASMVRVLEGQPASLPCVVLAGKPFPQRHWL 830 Query: 868 RNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + + + PS + DG +I+ + + D+G Y CV +N+ G S + + V+ Sbjct: 831 KEGQPL-PSSRYSIRTDGSFHIDRAL-----QEDAGRYSCVVTNTVG--SQRQDIELAVQ 882 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM----DHREIIQEGRXX 982 + + Y T EG + L C S + T +KE + + H ++++EG Sbjct: 883 VLPSILPTASHYVTNEGVPISLPC-VSRGIPTPTITWRKETNALSPRSSHHQVLKEG--- 938 Query: 983 XXXXXXXXXXDVGVIKCI------VKDQE------TSTMLVVKETIPEFIRKLQDFEVKE 1030 D G C + QE T +++ E++ + R + + Sbjct: 939 SLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESL-DSDRPVTITALAG 997 Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 K++ + S + + W +D +++ P +++ G ++ + TSV D G Y+CI Sbjct: 998 KELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLK---LAETSVEDNGLYTCI 1054 Query: 1091 LRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSE 1145 + + TA V V++PP+I Q KV G T GD +RW KDG Sbjct: 1055 ASNPAGTASRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVAT-GDPKPQLRWSKDGIT 1113 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201 + + G + + + D+G Y C E G L V EP + Sbjct: 1114 LPQKGWV-----GPDGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEPP-RWEAE 1167 Query: 1202 LPEFILV-PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 E +L A +A L + ++K E +S + +L I + Sbjct: 1168 DAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSS 1227 Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIK--RGSDVTLLVDYQAFPQP 1317 D +Y C + + KV++V + PP E+ + +TL D FP P Sbjct: 1228 QDSGDYECRATNEVGSVSRKVKLVVYVPPHFRGEEQRVNVSTLASRPLTLNCDVSGFPTP 1287 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W + + + + + + SL +V+ +D+ +Y + N G A + N+ + Sbjct: 1288 AITWYKDGRPVS--EDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLV 1345 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 L PS G E+ + E E S + VE+ + +I Sbjct: 1346 LIPPSVRGAGTAQEVS----RLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLV 1401 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494 + Q LK SS+ A V S A + + +++ +T PT+ + Sbjct: 1402 EDG-QVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQT---PPTIWGSNETGEVAVM 1457 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY-ENRXXXXXXXXXXXXXXXYKCIA 1552 + + L C GVP P +TW +DG L + + Y + Y C A Sbjct: 1458 EDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYAKGGRHLQLGRARGSDSGLYTCQA 1517 Query: 1553 FNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N G E + + + P I + K G + G PPP + W+++ N Sbjct: 1518 SNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDEN 1577 Query: 1612 KL-END--------------------KEY-NITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 L EN+ +E+ + +++RI ++ H+ + +A+N Sbjct: 1578 PLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATN 1637 Query: 1650 TAGTSSVEVTLKVYDKPS 1667 AGT+ EV + V+++PS Sbjct: 1638 EAGTAGAEVEVLVHEQPS 1655 Score = 168 bits (409), Expect = 1e-39 Identities = 275/1272 (21%), Positives = 461/1272 (36%), Gaps = 150/1272 (11%) Query: 466 KGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEK------LRPK 519 K W +YL N K N + P+F+K ++ E+ L + Sbjct: 2394 KAWDSGRYLCVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453 Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 + + C P PQ+TW++ +P D + L I V EDAG Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKDD---QPLSDIEGISVLQGGRVLQIPMVRSEDAG 2510 Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 +TC A N G EL+V P +++G P ++ Sbjct: 2511 RYTCKASNEVGEDWLHYELLVLTP-----------------------PVIQGDPEELVEE 2547 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-----------ISVAIESDM 688 V+ S + L+C+ + P P I+WL G +P +SVA +D Sbjct: 2548 VT---VNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQVLQVSVADAADS 2604 Query: 689 HMYCSV---------------------LKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 Y V L++ K GTYT A+N G ++L + Sbjct: 2605 ASYMCVAENSAGSSEKLFTLKVQGTHTLQLPRPKPSDTGTYTCEALNVAGRDQKLVLLSV 2664 Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDG 784 + +VR G++ +L + P P ITW KN + + + + T DG Sbjct: 2665 FAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDG 2724 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 I ++ V D+G+Y+ K N G A + V+ V+ P P+F N +E Sbjct: 2725 QKLEIVNVQ---VADKGLYSCKVSNIVGEAIRTFVLIVQVP-------PIFENPEKETLS 2774 Query: 845 KEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 + G + LV V P P++TW ++ + S G ++L E G Sbjct: 2775 QVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVSRGGRLQLSRLQPSQE---GT 2831 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST--KWY 961 Y CVA N ++ V + V + + + E + V LEC+ W Sbjct: 2832 YTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQEVRLECEAEGQPQPDISWL 2891 Query: 962 HNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIP 1017 + + + H +G D G C+ ++ E + + V +P Sbjct: 2892 KDGRPLGVHTAPHLRFYTDG--SSLVLKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVP 2949 Query: 1018 EFIRKLQD-----FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 I + + V+ + V + S + W +DG + P + G R Sbjct: 2950 PTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKDG-LPMPLSQRTHLHSSG--R 3006 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPP--EIITRLQNQKVNKGNKATFE 1127 L I V D G ++C+ + AE T + +PP E V +G+ T Sbjct: 3007 TLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLEPSETKDAMAVVRGSDVTLP 3066 Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 E +G L V W KDG+ + +L + G L++ DD G YSC N Sbjct: 3067 CE-ARGSPLPAVSWLKDGASLMLQ---RLGL-GSGSSLQLEAVQADDVGTYSCVAINEAG 3121 Query: 1186 TA-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 A + +E P I + + E +L+P + + ++TW K V+ Sbjct: 3122 EATRHFQLAVMEPPHIEDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLARLG 3181 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRI 1299 T R L + DD YTC+ + A K + V+ PP IV RE R Sbjct: 3182 SITKDG----RVLRVEGVQVDDAGLYTCLAENPAGEDGKNFLVRVQAPPNIVG-SRETRT 3236 Query: 1300 KRG-SDVTLLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 G +D L+++ +A P P EW +++ HT L ++ ++ +D+G Sbjct: 3237 VIGLADGQLVLECPVEADPPPKIEWHREGVLLQADAHTL--FLENGRFLQLQALDTSDSG 3294 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y N G + +V I P+ P+++ + + + + S + + Sbjct: 3295 DYNCVASNAAGSTSLPFSVEIHMAPTIQPGPSVVNVSVNETALLPCKTRGLPVSLVSWRK 3354 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + + + ++ IQ + S + A N SD +E Sbjct: 3355 DGIPLVPGSPRLEF--LSDGSLRIQPVYPQDSGYYLCQASNSAG-SDRQG--------RE 3403 Query: 1477 TKI-QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXX 1535 ++ + PT+ N+T + L C G P+P V W ++G+ L + R Sbjct: 3404 LRVFEPPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQTLSLDRHQEAYRLLP 3463 Query: 1536 XXXXXXX----XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 ++C+ ND GE V + P I D + Sbjct: 3464 SSSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYVPPTIADDRTDFTVTKMA--PVV 3521 Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 +T G+P P V W K G +L + Y ++ T + I++ H+ +YT A N Sbjct: 3522 LTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVS---PTGALEIEQALPIHTGRYTCTARNA 3578 Query: 1651 AGTSSVEVTLKV 1662 AG + V L V Sbjct: 3579 AGVAHKHVILMV 3590 Score = 144 bits (348), Expect = 3e-32 Identities = 258/1218 (21%), Positives = 444/1218 (36%), Gaps = 136/1218 (11%) Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G C V G P PQ W ++ + PS + + D + I EDAG + Sbjct: 808 EGQPASLPCVVLAGKPFPQRHWLKEGQPL-PSSRYSIRTD----GSFHIDRALQEDAGRY 862 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 +CV N G EL V+ +L I PT S Sbjct: 863 SCVVTNTVGSQRQDIELAVQ--------------------------VLPSILPTAS---- 892 Query: 642 AQYV-DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 YV +EG I L C IP P I W + + P + ++ L + Sbjct: 893 -HYVTNEGVPISLPCVSRGIPTPTITWRKETNALSPRSSHHQVLKEGS------LYLPQP 945 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEK----EPPQVIEPLKSMIVRQGESVILSA 756 GTY A N G +S I L + T + E P+ ++ G+ + L Sbjct: 946 SAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDSDRPV-TITALAGKELTLHC 1004 Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 + G+P P ITW K+++ + + + L V+D G+YT A N G A Sbjct: 1005 EAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAETSVEDNGLYTCIASNPAGTASR 1064 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 S V+ V+ P + P L + V ++ L T +P P + W ++ + Sbjct: 1065 SYVLGVQVPPQIQQGPQL-------LKVLAGESLDLTCVATGDPKPQLRWSKDGITLPQK 1117 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + DG ++ L V DSG Y CVAS+ AG+ + + + + + Sbjct: 1118 GWVGP--DG-SVHLESVQVS---DSGHYHCVASSEAGEDARELELEVLEPPRWEAEDAEA 1171 Query: 937 SYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-DHREIIQEGRXXXXXXXXXXXXDVG 995 E G+ L C + T + + K + + + D G Sbjct: 1172 LLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLFIASVSSQDSG 1231 Query: 996 VIKCIVKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSE-----TADVV 1048 +C ++ S VK + P R ++ V +A + +N + T + Sbjct: 1232 DYECRATNEVGSVSRKVKLVVYVPPHFRG-EEQRVNVSTLASRPLTLNCDVSGFPTPAIT 1290 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVEL 1105 W +DG + + N++ F L+ D Y+C + + A+ +V + Sbjct: 1291 WYKDGRPVS-EDNRHYFPDGAP--SLHFPQVQKSDSDLYTCQAVNPAGMAQKDFNLLVLI 1347 Query: 1106 PPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDGSEIQFSN-HIQLTIDGKKQ 1161 PP + Q+V++ E+E T G L V W KDG + + HIQL DG Q Sbjct: 1348 PPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVAPGDPHIQLVEDG--Q 1405 Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 LKI L DAG Y C G L+++ P + + V + L Sbjct: 1406 VLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPTIWGSNETGEVAVMEDHVVRLQ 1465 Query: 1218 VEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 + T +TW K + + + R L + + D YTC +A Sbjct: 1466 CDARGVPTPAITWLKDGDPLHASPRVAYAKG--GRHLQLGRARGSDSGLYTCQASNAAGI 1523 Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKR---GSDVTLLVDYQAFPQP--------------N 1318 + V + V PP I + + + G + L P P N Sbjct: 1524 AEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENPLTENN 1583 Query: 1319 DEWI-VNSKIIKKCKHTKPS-------IDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 W+ ++++ ++ +P+ + + A L I V+ G++ + N G A Sbjct: 1584 GTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLRIDHVQPDHNGLFACQATNEAGTAG 1643 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 E+ V + ++PS + ++ +I + +P TI + + W + Sbjct: 1644 AEVEVLVHEQPS------VTVLEGENITAPFLQP-----VTIQCVAAGMPVPNLSWWKNG 1692 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 ++ T S+Q K + Y +++ ++ KV + P +E L N Sbjct: 1693 VSLVTTGGSLQIEKVDLRDEGN-YTCVATNLAGEAKRDVVLKV-----LVPPNIEPGLVN 1746 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXY 1548 N L C+ GVP P+++WYR + + K + Y Sbjct: 1747 KAVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSSDGRVLRIKRAQLSDAGSY 1806 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 +C+A N G E + I P IT++ + + + + G P P ++W K Sbjct: 1807 RCVASNVAGSSELKFGLRINVPPRITLA-PSLPGPVLLNEPVRLVCNATGAPTPMLMWLK 1865 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 +GN + + V+ + + + + YT A N G +VTL+V+ PS Sbjct: 1866 DGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSI 1925 Query: 1669 PEGPVIMREISRESVTIE 1686 + + +SVT+E Sbjct: 1926 LGEEQNVSVVVNQSVTLE 1943 Score = 143 bits (347), Expect = 4e-32 Identities = 271/1266 (21%), Positives = 459/1266 (36%), Gaps = 150/1266 (11%) Query: 475 MDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVE 534 + E + Y+ K +NE L E AP VE R G C+ E Sbjct: 667 VQERDAGNYICKAVNE----LGAASADIRLEVGYAPRLVESSRNMVVEMGRNAILACRAE 722 Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P P+ITW R P+ + L + V PED + C A N G A Sbjct: 723 GRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFLENVTPEDQALYICEAHNTFGKAQ 782 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653 + +L V G E +LEG P + L Sbjct: 783 AEVQLTV------IGHEPP-----QIASSASMVRVLEGQPAS-----------------L 814 Query: 654 ECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 C ++A P P WL +G+ + P S+ + H I + G Y+ V Sbjct: 815 PCVVLAGKPFPQRHWLKEGQPL-PSSRYSIRTDGSFH-------IDRALQEDAGRYSCVV 866 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N G I L ++ P ++ + +G + L G P PTITW K Sbjct: 867 TNTVGSQRQDIELAVQV----LPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKET 922 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 + + L +D G Y A N+ GI+ ++V Sbjct: 923 NALSPRSSHHQVLKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNE 982 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 L +R IT + L +P P ITW ++++++SP +++L Sbjct: 983 SLDSDRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAE 1042 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 T+V+ D+G Y C+ASN AG +S + V+ ++ + + G+++ L C Sbjct: 1043 TSVE---DNGLYTCIASNPAGTASRS--YVLGVQVPPQIQQGPQLLKVLAGESLDLTCVA 1097 Query: 953 SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012 + + +K I+ + + + G D G C+ + + Sbjct: 1098 TGDPKPQLRWSKDGIT-LPQKGWV--GPDGSVHLESVQVSDSGHYHCVASSEAGEDAREL 1154 Query: 1013 KETIPEFIR-KLQDFEVKEKDVAILEVEI-----NSETADVVWERD--GEIIKPKKNKYD 1064 + + E R + +D E + VA + + T V+W +D E++ + Sbjct: 1155 ELEVLEPPRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSV 1214 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEV-TVVELPPEIITRLQNQKVNKG 1121 L+I + S D G+Y C +E S + +V VV +PP R + Q+VN Sbjct: 1215 LND----SSLFIASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPPHF--RGEEQRVNVS 1268 Query: 1122 NKATFEIEL---TKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 A+ + L G + W+KDG + N DG L D+ Y Sbjct: 1269 TLASRPLTLNCDVSGFPTPAITWYKDGRPVSEDNRHYFP-DG-APSLHFPQVQKSDSDLY 1326 Query: 1177 SCEVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWY 1230 +C+ N K +L + PS+ E + A + L L V W Sbjct: 1327 TCQAVNPAGMAQKDFNLLVLIPPSVRGAGTAQEVSRL-AGLEVELECRTSGVPLPQVEWT 1385 Query: 1231 KK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288 K + V L+ D + L I D Y CV ++ ++ PP Sbjct: 1386 KDGQPVAPGDPHIQLVED--GQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPP 1443 Query: 1289 KI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-- 1344 I + E + V L D + P P W+ + + H P + Sbjct: 1444 TIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKDGDPL----HASPRVAYAKGGRH 1499 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHA------DVEMNVTILDKPSPP-------GKPNILE 1391 L + + +D+G+Y + N G A DV + TI P G+P L Sbjct: 1500 LQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALG 1559 Query: 1392 IDSSS---INICWDEPEN---TGNSTIIY---YVVEY--QEIDTTEWISVKNITK-TQTS 1439 +S + W + EN N T + V+ + E+ V+ T Sbjct: 1560 CSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTDGAMLR 1619 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I +++ + + F A NE + A ++ T ++ +NIT + + Sbjct: 1620 IDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEG-------ENITAPFLQPV 1672 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 + C+ G+P P ++W+++G L T + + Y C+A N GE Sbjct: 1673 TIQCVAAGMPVPNLSWWKNGVSLVTTGGSLQ------IEKVDLRDEGNYTCVATNLAGEA 1726 Query: 1560 ETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 + V+ + P I + N+ + + E L + G+P P + WY+ + + Sbjct: 1727 KRDVVLKVLVPPNIEPGLVNKAVLENTSASLECLAS----GVPTPRISWYRGRQPISSKP 1782 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEG 1671 +++ + V+RIK + S + Y ASN AG+S ++ L++ PS P G Sbjct: 1783 GLMVSSDGR--VLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLP-G 1839 Query: 1672 PVIMRE 1677 PV++ E Sbjct: 1840 PVLLNE 1845 Score = 136 bits (329), Expect = 6e-30 Identities = 255/1257 (20%), Positives = 454/1257 (36%), Gaps = 116/1257 (9%) Query: 476 DENNYTQYLQKKLNEKIDK--LPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 D YT + ++ E + + V P+ S++ + V++++ K ST+ EC+ Sbjct: 2299 DAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVN---STLSLECE 2355 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 P P ITW++ ++ P + D L I D+G + CVA N AG Sbjct: 2356 SWAMPPPTITWYKDGQLVSPDNRLHLLADG---RLLQINPTKAWDSGRYLCVATNVAGED 2412 Query: 593 SSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 ++V+ P+ + +LE + + E + Sbjct: 2413 DKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLE-----------YREIVENNPA 2461 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 L C A+P P + W +K ++ + D E ISV VL+I V+ G YT Sbjct: 2462 YLYCDTNAVPPPQLTW-YKDDQPLSDIEGISVLQGG------RVLQIPMVRSEDAGRYTC 2514 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A N GE L L + T E ++ + V +V L Q +G P P I+W + Sbjct: 2515 KASNEVGEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLR 2574 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE------TSAVITVEE 824 N P + + + D Y AENS G +E T++ Sbjct: 2575 NGLPFIPSSKHQALEDGQVLQVSVADAADSASYMCVAENSAGSSEKLFTLKVQGTHTLQL 2634 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P + ++ + + +++ + L + R+ ++ +T + + Sbjct: 2635 PRPKPSDTGTYTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCE 2694 Query: 885 GENI-ELVIT------------NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV--T 929 + + E VIT V + +D + V A K + +V+ V + T Sbjct: 2695 SDTLPEPVITWYKNGQQIALDQQVQTLLDGQKLEIVNVQVADKGLYSCKVSNIVGEAIRT 2754 Query: 930 FVKHLQ--KSYETEE--------GKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQ 977 FV +Q +E E G ++L C + + W ++ + R ++ Sbjct: 2755 FVLIVQVPPIFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWLKDRMPVESSVERGVVS 2814 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRK--LQDFEVKEKD 1032 G G C+ ++ E +V+ P + Q+ + E+ Sbjct: 2815 RG--GRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPRILSSGVPQEHNILEEQ 2872 Query: 1033 VAILEVEINSE-TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 LE E + D+ W +DG + + F G L ++ D G Y+C+ Sbjct: 2873 EVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDG--SSLVLKGLKSSDSGAYTCL 2930 Query: 1091 LRDE--SCTAEVTVVELPPEIITRLQNQKVN----KGNKATFEIELTKGDAL-VRWFKDG 1143 ++ T TV L P I R N N +G T + + W KDG Sbjct: 2931 AQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACPARGSPPIQINWLKDG 2990 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFT 1199 + S L G+ L+I + DAG ++C G ++ T L + P + Sbjct: 2991 LPMPLSQRTHLHSSGR--TLRISQVQVADAGTFTCVASSPAGVAERTFSLQIHVPPVLEP 3048 Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 + + V +D L E L V+W K + + ++ L S +L + Sbjct: 3049 SETKDAMAVVRGSDVTLPCEARGSPLPAVSWLKDGASLM-LQRLGLGSG---SSLQLEAV 3104 Query: 1259 TEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVD--YEREYRIKRGSDVTLLVDYQAF 1314 DD Y+CV ++ ++T ++ V+E PP I D E + G+ + L+ + Sbjct: 3105 QADDVGTYSCVAINEAGEATRHFQLAVME-PPHIEDSGQAEEMLLLPGAPLELICNALGS 3163 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P PN W + +++ + SI L ++ V+ DAG+Y EN G Sbjct: 3164 PMPNITWQKDGQVLARL----GSITKDGRVLRVEGVQVDDAGLYTCLAENPAGEDGKNFL 3219 Query: 1375 VTILDKPSPPG-KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT-TEWISVKN 1432 V + P+ G + I + + + P I + E + + ++N Sbjct: 3220 VRVQAPPNIVGSRETRTVIGLADGQLVLECPVEADPPPKIEWHREGVLLQADAHTLFLEN 3279 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 Q +Q L T+ S + A N + + E + +PT++ + Sbjct: 3280 GRFLQ--LQALDTSDSGDYNCVASNAAGSTSLPFSVEIH--------MAPTIQPGPSVVN 3329 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKC 1550 NE L C G+P V+W +DG L E + Y C Sbjct: 3330 VSVNETALLPCKTRGLPVSLVSWRKDGIPLVPGSPRLEFLSDGSLRIQPVYPQDSGYYLC 3389 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 A N G + + + P I ++ V + + G P P V+W KNG Sbjct: 3390 QASNSAGSDRQGRELRVFEPPTIAPGPSNLTL--TVHTQATLPCEARGSPKPHVVWKKNG 3447 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 L D+ +S + + + ++++ SN AG + + VY P+ Sbjct: 3448 QTLSLDRHQEAYRLLPSSSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYVPPT 3504 Score = 117 bits (282), Expect = 3e-24 Identities = 176/801 (21%), Positives = 303/801 (37%), Gaps = 88/801 (10%) Query: 633 PPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 PPT S + V E + L+C +P P I WL G+ + ++ A + H Sbjct: 1442 PPTIWGSNETGEVAVMEDHVVRLQCDARGVPTPAITWLKDGDPLHASPRVAYA-KGGRH- 1499 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L++ + G YT A N G A + L + PL V G Sbjct: 1500 ----LQLGRARGSDSGLYTCQASNAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVA-GR 1554 Query: 751 SVILSAQVVGNPRPTITW------------------------CKNNKPVK---ALPTKSD 783 + L G+P PT+TW +N +P + + +D Sbjct: 1555 PLALGCSASGHPPPTLTWHQDENPLTENNGTWLQEGGRVLRWLRNGRPAEEFAGVEVSTD 1614 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G I ++P G++ +A N G A + V E +P + + + IT Sbjct: 1615 GAMLRIDHVQPDH---NGLFACQATNEAGTAGAEVEVLVHE------QPSVTVLEGENIT 1665 Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 + + PVP+++W++N +S T G +++ I VD D G+ Sbjct: 1666 APFLQPVTIQCVAAGMPVPNLSWWKNG--VSLVTT------GGSLQ--IEKVDLR-DEGN 1714 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWY 961 Y CVA+N AG++ + + V + K+ E + LEC S T WY Sbjct: 1715 YTCVATNLAGEAKRDVVLKVLVPPNIEPGLVNKA--VLENTSASLECLASGVPTPRISWY 1772 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLV--VKETIPEF 1019 ++ IS + +GR D G +C+ + S+ L ++ +P Sbjct: 1773 RGRQPISSKPGLMVSSDGRVLRIKRAQLS--DAGSYRCVASNVAGSSELKFGLRINVPPR 1830 Query: 1020 IR---KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK-YDFEKRGHIRKLY 1075 I L + + V ++ + T ++W +DG + GH+ L Sbjct: 1831 ITLAPSLPGPVLLNEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHV--LT 1888 Query: 1076 IRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTK 1132 + + D G Y+C+ + +VT+ V LPP I+ QN V T E + Sbjct: 1889 LAGSRATDAGTYTCVAVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLECQSQA 1948 Query: 1133 -GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187 ++ W KDG + + L+ DG L++ ++ D G Y+CE G S+ Sbjct: 1949 VPPPVLSWRKDGHALSPRPGVHLSADGVL--LQVERAEVQDVGRYTCEALNKAGRSEKHY 2006 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLIS 1246 L V P F+ P + V L+ E +TW K ++ T Sbjct: 2007 NLNVWVPP-EFSFWEPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPI 2065 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVL--LDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRG 1302 R L + K + YTC + S+ + +EV P P D+ +E + Sbjct: 2066 SAVGRLLYLGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHS 2125 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 +VTL + P P W + +++ + + + + +L +++ AG Y Sbjct: 2126 GEVTLECEATGKPPPVVTWEKDGQLVTRDQGLL--LQHRGRALQVEQARAAHAGRYTCIA 2183 Query: 1363 ENNCGHADVEMNVTILDKPSP 1383 EN G A+ ++++L PSP Sbjct: 2184 ENEAGRAEQRFDLSVLGNPSP 2204 Score = 116 bits (279), Expect = 7e-24 Identities = 178/806 (22%), Positives = 300/806 (37%), Gaps = 67/806 (8%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V+ +C G P P ITW + + S ++ Y L + D+G +TC A Sbjct: 1462 VRLQCDARGVPTPAITWLKDGDPLHASP--RVAYAKGG-RHLQLGRARGSDSGLYTCQAS 1518 Query: 587 NAAGFASSTTELIVEAPLSDHGSE--MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 NAAG A L V P + G++ V PPT + Sbjct: 1519 NAAGIAEKAVRLDVYVPPTIEGADGGPLVVKAVAGRPLALGCSASGHPPPTLTWHQDENP 1578 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + E + L+ + WL G +E V + +D M L+I +V+ Sbjct: 1579 LTENNGTWLQ-----EGGRVLRWLRNGRPA--EEFAGVEVSTDGAM----LRIDHVQPDH 1627 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G + A N G A + + + ++P + +++ + V + G P P Sbjct: 1628 NGLFACQATNEAGTAGAEVEVLV---HEQPSVTVLEGENITAPFLQPVTIQCVAAGMPVP 1684 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 ++W KN V + T S+ I K ++DEG YT A N G A+ V+ V Sbjct: 1685 NLSWWKNG--VSLVTTGG-----SLQIEK-VDLRDEGNYTCVATNLAGEAKRDVVLKVLV 1736 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P N EP L +N+ V E + L + P P I+WYR + IS + + D Sbjct: 1737 P--PNIEPGL-VNK----AVLENTSASLECLASGVPTPRISWYRGRQPISSKPGLMVSSD 1789 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKS--SHGARVTIDVEKVTFVKHLQKSYETEE 942 G + + + D+G Y+CVASN AG S G R+ + ++T L E Sbjct: 1790 GRVLRIKRAQLS---DAGSYRCVASNVAGSSELKFGLRINVP-PRITLAPSLPGPVLLNE 1845 Query: 943 GKTVILECQTSHTVSTKWYHNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 ++ + T W + +S G +I G D G C+ Sbjct: 1846 PVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGH--VLTLAGSRATDAGTYTCV 1903 Query: 1001 VKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEII 1056 + ++ + + P + + Q+ V LE + + V+ W +DG + Sbjct: 1904 AVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTLECQSQAVPPPVLSWRKDGHAL 1963 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI-ITR 1112 P+ + G + L + V D G Y+C +++ +E V +PPE Sbjct: 1964 SPRPGVH-LSADGVL--LQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWVPPEFSFWE 2020 Query: 1113 LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 + V +G+ + E + W KDG + I + L + Sbjct: 2021 PRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLYLGKAQPS 2080 Query: 1172 DAGEYSCE----VGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 G Y+CE GNS L V P + + + + V + + L E + Sbjct: 2081 QEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGEVTLECEATGKPPP 2140 Query: 1227 -VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283 VTW K ++ T L+ + R L + + YTC+ + ++ + + V Sbjct: 2141 VVTWEKDGQLV--TRDQGLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAEQRFDLSV 2198 Query: 1284 VEFPPKIVDYER-EYRIKRGSDVTLL 1308 + P ++ + R E I G DV L Sbjct: 2199 LGNPSPLIRWFRGEEPISPGEDVYFL 2224 Score = 114 bits (274), Expect = 3e-23 Identities = 209/1071 (19%), Positives = 400/1071 (37%), Gaps = 90/1071 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP P+ V G LL C+++ ++ W+ + ++P V +++ Sbjct: 428 PPPQLASPQNVTVSPGETALLSCQVLDKAPYNLTWV-RDWRVLPASPGRVVQLANLS--- 483 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L+I+ + G Y +A N G + L I+ EPPQ+ S QG + Sbjct: 484 --LEISGIIPSDGGKYQCLASNANGITRASVWLLIR----EPPQISINTSSRHFSQGVEL 537 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 +S G P P I+W N++ + + + D I++ +D G Y+ +A N G Sbjct: 538 RISCTASGYPPPHISWRHNDQTI-GMDGRFLVDDQGTLIIQSVTPEDAGNYSCQATNEVG 596 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN--N 870 E + + EP +A P+ + E V E + + P P + WYR Sbjct: 597 TDEQTVTLFYTEPPSVSALRPVVLAPIGEEAVLE-------CKASGVPPPRVIWYRGGLE 649 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I++P T + ++ E D+G+Y C A N G +S A + ++V Sbjct: 650 MILAPEVAHTGTLRIQEVQ--------ERDAGNYICKAVNELGAAS--ADIRLEVGYAPR 699 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTK--W--YHNKKEISGMDHREIIQEGRXXXXXX 986 + ++ E G+ IL C+ S + W K + ++ Sbjct: 700 LVESSRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAHPVEGNRARQLEAGVLFL 759 Query: 987 XXXXXXDVGVIKC-----IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE--VE 1039 D + C K Q + V+ P+ V E A L V Sbjct: 760 ENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQPASLPCVVL 819 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 W ++G+ + ++Y G +I D G YSC++ + + Sbjct: 820 AGKPFPQRHWLKEGQPL--PSSRYSIRTDG---SFHIDRALQEDAGRYSCVVTNTVGSQR 874 Query: 1100 VTV---VELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ-FSNHIQ 1153 + V++ P I+ + N+G + +++G + W K+ + + S+H Q Sbjct: 875 QDIELAVQVLPSILPTASHYVTNEGVPISLPC-VSRGIPTPTITWRKETNALSPRSSHHQ 933 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-----EPSI--NFTLRLPEFI 1206 + +G L + D+G Y C N+ + ++ +P I N +L + Sbjct: 934 VLKEG---SLYLPQPSAQDSGTYVCTATNALGISSQEIQLSVNTKPRIIMNESLDSDRPV 990 Query: 1207 LVPANTDAYLTVEIPDETLD---VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDD 1262 + A LT+ E +TW K ++ T++ +L+ +L + + + +D Sbjct: 991 TITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLL---PSGSLKLAETSVED 1047 Query: 1263 QCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 YTC+ + A + ++ V V+ PP+I + ++ G + L P+P W Sbjct: 1048 NGLYTCIASNPAGTASRSYVLGVQVPPQIQQGPQLLKVLAGESLDLTCVATGDPKPQLRW 1107 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + + + P S+ ++ V+ +D+G Y + G E+ + +L+ P Sbjct: 1108 SKDGITLPQKGWVGP-----DGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEPP 1162 Query: 1382 --SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQT 1438 +LE + T +I+ E+ +++ +SV N + Sbjct: 1163 RWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLN--DSSL 1220 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 I ++ + S + A NEV + K++ E+ + N++T + Sbjct: 1221 FIASVSSQDSGDYECRATNEV-----GSVSRKVKLVVYVPPHFRGEEQRV-NVSTLASRP 1274 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + L C G P P +TWY+DG+ + Y + Y C A N Sbjct: 1275 LTLNCDVSGFPTPAITWYKDGRPVSEDNRHYFPDGAPSLHFPQVQKSDSDLYTCQAVNPA 1334 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + + + P + + + G E + G+P P+V W K+G + Sbjct: 1335 GMAQKDFNLLVLIPPSVRGAGTAQEVSRLAGLEVELECRTSGVPLPQVEWTKDGQPVA-P 1393 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + +I E V++I + Y A + AG + + L + P+ Sbjct: 1394 GDPHIQLVEDGQVLKIPSSHLGDAGHYQCVAFSPAGQQAKDFQLSIQTPPT 1444 Score = 105 bits (252), Expect = 1e-20 Identities = 141/686 (20%), Positives = 273/686 (39%), Gaps = 52/686 (7%) Query: 1028 VKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 V+ D A+L E ++ V+ W ++G+ I + +KL I N V D+G Sbjct: 2683 VRVGDTAVLHCESDTLPEPVITWYKNGQQIALDQQVQTLLDG---QKLEIVNVQVADKGL 2739 Query: 1087 YSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNK--GNKATFEIELTKGDA-LVRWF 1140 YSC + + E+ V +V++PP I + + +++ GN ++ A V W Sbjct: 2740 YSCKVSNIVGEAIRTFVLIVQVPP-IFENPEKETLSQVAGNPLVLVCDVAGVPAPTVTWL 2798 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPS 1195 KD ++ S ++ + + +L++ G Y+C N + A ++ + P Sbjct: 2799 KDRMPVESS--VERGVVSRGGRLQLSRLQPSQEGTYTCVAENPEAEARKDFVVMVLVAPR 2856 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 I + +P+ + + L E + D++W K + L +L+ Sbjct: 2857 I-LSSGVPQEHNILEEQEVRLECEAEGQPQPDISWLKDGRPLGVHTAPHLRFYTDGSSLV 2915 Query: 1255 IRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFPPKI---VDYEREYRIKRGSDVTLLVD 1310 ++ D YTC+ ++ TKL V PP I + +G VT+ Sbjct: 2916 LKGLKSSDSGAYTCLAQNSVGEDTKLHTVSVLVPPTIERGANGSENLISVQGELVTMACP 2975 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 + P W+ + + + T + S +L I +V+ DAG + + G A+ Sbjct: 2976 ARGSPPIQINWLKDGLPMPLSQRTH--LHSSGRTLRISQVQVADAGTFTCVASSPAGVAE 3033 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 ++ I P +LE + + G+ + + W+ Sbjct: 3034 RTFSLQI-------HVPPVLEPSETKDAMAVVR----GSDVTLPCEARGSPLPAVSWL-- 3080 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVD------ISDASETTEYYKVIKETKIQSPTV 1484 K+ L + SS + A ++V I++A E T ++++ ++ P + Sbjct: 3081 KDGASLMLQRLGLGSGSSLQLEAVQADDVGTYSCVAINEAGEATRHFQL---AVMEPPHI 3137 Query: 1485 EKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542 E + + P +EL C G P P +TW +DG+ L + ++ Sbjct: 3138 EDSGQAEEMLLLPGAPLELICNALGSPMPNITWQKDGQVLARLGSITKDGRVLRVEGVQV 3197 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 Y C+A N GE + +V +Q P I S E + ++ +E PPP Sbjct: 3198 DDAGLYTCLAENPAGEDGKNFLVRVQAPPNIVGSRETRTVIGLADGQLVLECPVEADPPP 3257 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ W++ G L+ D + E ++++ L S S Y ASN AG++S+ ++++ Sbjct: 3258 KIEWHREGVLLQADA--HTLFLENGRFLQLQALDTSDSGDYNCVASNAAGSTSLPFSVEI 3315 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWK 1688 + P+ GP ++ E+ + K Sbjct: 3316 HMAPTIQPGPSVVNVSVNETALLPCK 3341 Score = 99.5 bits (237), Expect = 9e-19 Identities = 186/936 (19%), Positives = 350/936 (37%), Gaps = 85/936 (9%) Query: 771 NNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYT-LKAENSEGIAETSAVITVEEPTE 827 + +P+ LP S +T H + + P +V E Y +K E+ EG V V Sbjct: 366 SGQPLLTLPAGSLSNTSSHQLWVGPPFRVPKERFYLKVKGEDHEG-NPLHRVSNVAYNGV 424 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDG 885 PP + Q +TV T L +V ++TW R+ ++ SP + Sbjct: 425 APDPPPQLASP-QNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQL---- 479 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 N+ L I+ + D G Y+C+ASN+ G + A V + + + + S +G Sbjct: 480 ANLSLEISGIIPS-DGGKYQCLASNANGITR--ASVWLLIREPPQISINTSSRHFSQGVE 536 Query: 946 VILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC---- 999 + + C S W HN + I GMD R ++ + D G C Sbjct: 537 LRISCTASGYPPPHISWRHNDQTI-GMDGRFLVDD--QGTLIIQSVTPEDAGNYSCQATN 593 Query: 1000 -IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG--EI 1055 + D++T T+ + +R + + E+ A+LE + + V+W R G I Sbjct: 594 EVGTDEQTVTLFYTEPPSVSALRPVVLAPIGEE--AVLECKASGVPPPRVIWYRGGLEMI 651 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITR 1112 + P+ H L I+ D G Y C +E + +A++ + V P ++ Sbjct: 652 LAPEV--------AHTGTLRIQEVQERDAGNYICKAVNELGAASADIRLEVGYAPRLVES 703 Query: 1113 LQNQKVNKGNKATFEIELT-KGDALVRWFK-DGSEIQFSNHIQLTIDGKKQK------LK 1164 +N V G A + + W + DG + ++G + + L Sbjct: 704 SRNMVVEMGRNAILACRAEGRPSPRITWARVDGKPVPAH-----PVEGNRARQLEAGVLF 758 Query: 1165 IYDCDLDDAGEYSCEV----GNSKCTAILTV---EEPSINFTLRLPEFIL-VPANTDAYL 1216 + + +D Y CE G ++ LTV E P I + + + PA+ + Sbjct: 759 LENVTPEDQALYICEAHNTFGKAQAEVQLTVIGHEPPQIASSASMVRVLEGQPASLPCVV 818 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 P W K+ + + ++++ +D + I + ++D Y+CV+ + + Sbjct: 819 LAGKPFPQRH--WLKEGQPL-PSSRYSIRTD---GSFHIDRALQEDAGRYSCVVTNTVGS 872 Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHT 1334 + +E+ V+ P I+ Y G ++L + P P W + + + H Sbjct: 873 QRQDIELAVQVLPSILPTASHYVTNEGVPISLPCVSRGIPTPTITWRKETNALSPRSSHH 932 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + K SL + + D+G Y N G + E+ +++ KP I+ +S Sbjct: 933 QV---LKEGSLYLPQPSAQDSGTYVCTATNALGISSQEIQLSV------NTKPRIIMNES 983 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + G ++ E W + T +L + S + Sbjct: 984 LDSDRPVTITALAGKELTLHCEAEGSPSPLITWTKDSQLLSPITDRHSLLPSGSLKLAET 1043 Query: 1455 AVNE----VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 +V + I+ T + ++ P +++ + + E ++LTC+ G P+ Sbjct: 1044 SVEDNGLYTCIASNPAGTASRSYVLGVQV-PPQIQQGPQLLKVLAGESLDLTCVATGDPK 1102 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 P++ W +DG L K Y C+A ++ GE + + + Sbjct: 1103 PQLRWSKDGITL-PQKGWVGPDGSVHLESVQVSDSGHYHCVASSEAGEDARELELEVLEP 1161 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P + + + G+ + + G P P VIW K+ + ++ +S+ Sbjct: 1162 PRWEAEDAEALLERVAGENASLPCPVTGTPTPRVIWRKDPAPELLSSQPGLSVLNDSSLF 1221 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 I + S Y A+N G+ S +V L VY P Sbjct: 1222 -IASVSSQDSGDYECRATNEVGSVSRKVKLVVYVPP 1256 Score = 88.6 bits (210), Expect = 2e-15 Identities = 112/440 (25%), Positives = 168/440 (38%), Gaps = 66/440 (15%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQ-------------------MYYDDDNVATL 568 +F+ V G P P I WFR I P +D +Y N + L Sbjct: 2193 RFDLSVLGNPSPLIRWFRGEEPISPGEDVYFLAGGRILKLTRVQEEEGGLYMCLANGSLL 2252 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL---------IVEAPLSDHGS-EMTVXXXXX 618 I + +G ++C+A N+ + +L I+ A D G V Sbjct: 2253 EILQANFSSSGHYSCIASNSVSEKTKHYKLSVLGTHGLQILNAQEQDAGRYTCVVTNEVG 2312 Query: 619 XXXXXXXADILEGIPPTFSKK-PKAQY-VDE-----GSDILLECRLVAIPEPDIAWLFKG 671 ++L IPP+ SK P ++ V E S + LEC A+P P I W G Sbjct: 2313 EAVKNYHVEVL--IPPSISKDDPLDEFSVKEVKAKVNSTLSLECESWAMPPPTITWYKDG 2370 Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL---------P 722 + + PD + + + +L+I K + G Y VA N GE P Sbjct: 2371 QLVSPDNRLHLLADG------RLLQINPTKAWDSGRYLCVATNVAGEDDKDFNVLVQVPP 2424 Query: 723 IVLKIKTGEK--EPPQVIEPLKSMIVRQGESV-----ILSAQVVGNPRPTITWCKNNKPV 775 I KI + E E L+ ++ E V L P P +TW K+++P+ Sbjct: 2425 IFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDTNAVPPPQLTWYKDDQPL 2484 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + S + + + +D G YT KA N G + V P +P Sbjct: 2485 SDIEGISVLQGGRVLQIPMVRSEDAGRYTCKASNEVGEDWLHYELLVLTPPVIQGDPEEL 2544 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 + +E+TV T+ L + P P I+W RN PS DG+ +++ +V Sbjct: 2545 V---EEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSSKHQALEDGQVLQV---SV 2598 Query: 896 DSEIDSGDYKCVASNSAGKS 915 DS Y CVA NSAG S Sbjct: 2599 ADAADSASYMCVAENSAGSS 2618 Score = 85.0 bits (201), Expect = 2e-14 Identities = 125/590 (21%), Positives = 219/590 (37%), Gaps = 50/590 (8%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 PP +T Q++ N T+ L +G ++RW ++G + ++++ DG L+I Sbjct: 1566 PPPTLTWHQDENPLTENNGTW---LQEGGRVLRWLRNGRPAEEFAGVEVSTDGAM--LRI 1620 Query: 1166 YDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYLT-VE 1219 D G ++C+ N TA +L E+PS+ T+ E I P + V Sbjct: 1621 DHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSV--TVLEGENITAPFLQPVTIQCVA 1678 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 +++W+K + T I V R D+ YTCV + K Sbjct: 1679 AGMPVPNLSWWKNGVSLVTTGGSLQIEKVDLR----------DEGNYTCVATNLAGEAKR 1728 Query: 1280 KVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS- 1337 V + V PP I + + +L P P W + I +KP Sbjct: 1729 DVVLKVLVPPNIEPGLVNKAVLENTSASLECLASGVPTPRISWYRGRQPIS----SKPGL 1784 Query: 1338 -IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEID 1393 + S L IK+ + +DAG Y+ N G ++++ + I P P P + ++ Sbjct: 1785 MVSSDGRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLPGPVLLN 1844 Query: 1394 SSSINICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRF 1451 +C TG T ++ ++ + + T ++ ++ + + + Sbjct: 1845 EPVRLVC----NATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTY 1900 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 AVN V T + + P++ +N++ N+ + L C VP P Sbjct: 1901 TCVAVNAVGEDRRDVTLQVHL--------PPSILGEEQNVSVVVNQSVTLECQSQAVPPP 1952 Query: 1512 KVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 ++W +DG L + + Y C A N G E + + Sbjct: 1953 VLSWRKDGHALSPRPGVHLSADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVWV 2012 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 P + E G ++ GIP P++ W K+G + D + Sbjct: 2013 PPEFSFW-EPRTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRL 2071 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 + + + + S YT E SN AG SS E L+VY P P +E+S Sbjct: 2072 LYLGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVS 2121 Score = 81.0 bits (191), Expect = 3e-13 Identities = 80/316 (25%), Positives = 123/316 (38%), Gaps = 36/316 (11%) Query: 527 VQFECQVEGYPRPQITWFRQTAII-KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 V C G P P ++W + A + K +++ L I + P G +TC A Sbjct: 3520 VVLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRV----SPTGALEIEQALPIHTGRYTCTA 3575 Query: 586 KNAAGFASSTTELIVE----------------APLSDHGSEMTVXXXXXXXXXXXXADIL 629 +NAAG A L+V+ A D G+ + + ++ Sbjct: 3576 RNAAGVAHKHVILMVQGTGAQILSSGQLRISRASAEDAGNYLCIAKNPSGTALGKTRLVV 3635 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 + +PP EGS LL C IPEP I W K +VP I+ Sbjct: 3636 Q-VPPVIKGGHSDLSAAEGSQALLPCIAQGIPEPHITWK-KDGFVVPSMEGKYTIQPS-- 3691 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L + N ++ GTYT +A N G S + L I + P + + G Sbjct: 3692 ---GELLVKNSERRDAGTYTCIAENAAGHTSRRVHLSILS----LPTFTTLPGDLSLNHG 3744 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK-DEGVYTLKAE 808 + + L G+P P I+W NN+ VK + DG + T+ + + D G YT AE Sbjct: 3745 DRLWLRCTARGSPTPHISWMVNNRLVKEGVLEQDGGS---TLQRAAVTREDSGTYTCWAE 3801 Query: 809 NSEGIAETSAVITVEE 824 N G + + + V+E Sbjct: 3802 NIVGKVQAVSFVHVKE 3817 Score = 77.0 bits (181), Expect = 5e-12 Identities = 123/612 (20%), Positives = 227/612 (37%), Gaps = 44/612 (7%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTA--EVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131 L I + G ++C +E+ TA EV V+ +T L+ + + I+ Sbjct: 1618 LRIDHVQPDHNGLFACQATNEAGTAGAEVEVLVHEQPSVTVLEGENITAPFLQPVTIQCV 1677 Query: 1132 KGDALV---RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184 V W+K+G + +T G Q K+ DL D G Y+C G +K Sbjct: 1678 AAGMPVPNLSWWKNGVSL-------VTTGGSLQIEKV---DLRDEGNYTCVATNLAGEAK 1727 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFT 1243 +L V P N L ++ NT A L T ++WY+ + I Sbjct: 1728 RDVVLKVLVPP-NIEPGLVNKAVLE-NTSASLECLASGVPTPRISWYRGRQPISSKPGLM 1785 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYEREYRIKR 1301 + SD R L I++ D Y CV + +++LK + + PP+I + + Sbjct: 1786 VSSD--GRVLRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVPPRITLAPSLPGPVLL 1843 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 V L+ + P P W+ + + + I LT+ TDAG Y Sbjct: 1844 NEPVRLVCNATGAPTPMLMWLKDGNPVSATGTSGLQIFPGGHVLTLAGSRATDAGTYTCV 1903 Query: 1362 LENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 N G ++ + + PS G+ N+ + + S+ + + ++ + + Sbjct: 1904 AVNAVGEDRRDVTLQVHLPPSILGEEQNVSVVVNQSVTL--ECQSQAVPPPVLSWRKDGH 1961 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 + + + + ++ + R+ A+N+ S+ + V E Sbjct: 1962 ALSPRPGVHL-SADGVLLQVERAEVQDVGRYTCEALNKAGRSEKHYNLNVW-VPPEFSFW 2019 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540 P + + + L+C G+P PK+TW +DG + T + E Sbjct: 2020 EP------RTLAVTEGHPVSLSCECWGIPFPKITWKKDGMLVPTDGGSTEPISAVGRLLY 2073 Query: 1541 XXXXXXX----YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAV 1595 Y C N G + + P + S++ K+ + E + Sbjct: 2074 LGKAQPSQEGNYTCECSNIAGNSSQEQHLEVYVAPKVPGSSDFHKEVSVIHSGEVTLECE 2133 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 G PPP V W K+G + D+ + + + +++++ + +H+ +YT A N AG + Sbjct: 2134 ATGKPPPVVTWEKDGQLVTRDQ--GLLLQHRGRALQVEQARAAHAGRYTCIAENEAGRAE 2191 Query: 1656 VEVTLKVYDKPS 1667 L V PS Sbjct: 2192 QRFDLSVLGNPS 2203 Score = 69.7 bits (163), Expect = 8e-10 Identities = 75/342 (21%), Positives = 138/342 (40%), Gaps = 37/342 (10%) Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 TH + IL ++ +D G YT N G A + + V P + + PL +E+ K Sbjct: 2287 THGLQILNAQE-QDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAK 2345 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 T+ L P P+ITWY++ +++SP + DG +++ N DSG Y Sbjct: 2346 VNSTLSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQI---NPTKAWDSGRYL 2402 Query: 906 CVASNSAGKSSHGARVTIDVEKV---------TFVKHLQKS---------YETEEGKTVI 947 CVA+N AG+ V + V + F H Q+ E E Sbjct: 2403 CVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAY 2462 Query: 948 LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 L C T+ + WY + + +S ++ ++Q GR D G C ++ Sbjct: 2463 LYCDTNAVPPPQLTWYKDDQPLSDIEGISVLQGGR--VLQIPMVRSEDAGRYTCKASNEV 2520 Query: 1006 TSTMLVVKETI--PEFIR-----KLQDFEVKEKDVAILEVE-INSETADVVWERDGEIIK 1057 L + + P I+ +++ V L+ + + + T + W R+G Sbjct: 2521 GEDWLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFI 2580 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 P +K+ + G + ++ + + + D Y C+ + + ++E Sbjct: 2581 P-SSKHQALEDGQVLQVSVADAA--DSASYMCVAENSAGSSE 2619 Score = 65.7 bits (153), Expect = 1e-08 Identities = 95/465 (20%), Positives = 173/465 (37%), Gaps = 39/465 (8%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+ G P+P + W + + + + Y + ++LV+ + +D F C+ N AG Sbjct: 3431 CEARGSPKPHVVWKKNGQTLSLDRHQEAYRLLPS-SSLVLTDPDLQDTAQFECLVSNDAG 3489 Query: 591 FASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTFS-KKPKAQYVD 646 + V P ++D ++ TV G+P P S K AQ Sbjct: 3490 ETRRLFWVTVYVPPTIADDRTDFTVTKMAPVVLTCHTT----GVPTPVVSWSKGGAQLGK 3545 Query: 647 EGSDI------LLEC-RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV--LKI 697 GS LE + + I + V +++ + ++ S L+I Sbjct: 3546 RGSGYRVSPTGALEIEQALPIHTGRYTCTARNAAGVAHKHVILMVQGTGAQILSSGQLRI 3605 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 + G Y +A N G A + K + + PP + + +G +L Sbjct: 3606 SRASAEDAGNYLCIAKNPSGTA----LGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPCI 3661 Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 G P P ITW K+ V ++ K ++K + +D G YT AEN+ G Sbjct: 3662 AQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKNSERRDAGTYTCIAENAAGHTSRR 3721 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 +++ P F ++++ + L +P P I+W NN ++ E Sbjct: 3722 VHLSI-------LSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLV--KE 3772 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 + + G ++ + DSG Y C A N GK A + V++ ++ S Sbjct: 3773 GVLEQDGGSTLQRAAVTRE---DSGTYTCWAENIVGKVQ--AVSFVHVKEAPALQGEASS 3827 Query: 938 YETE-EGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEG 979 + E G + L+C + +W + + H+ +Q G Sbjct: 3828 HLVELLGDSARLDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNG 3872 Score = 64.5 bits (150), Expect = 3e-08 Identities = 64/264 (24%), Positives = 109/264 (41%), Gaps = 23/264 (8%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXX 1539 P + P +N+T P E L+C +TW RD + L + + Sbjct: 430 PQLASP-QNVTVSPGETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLANLSLEISG 488 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y+C+A N +G S + I++ P I+I+ + G E ++ G Sbjct: 489 IIPSDGGKYQCLASNANGITRASVWLLIREPPQISINTSS--RHFSQGVELRISCTASGY 546 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 PPP + W N + D + + + + I+ + + Y+ +A+N GT VT Sbjct: 547 PPPHISWRHNDQTIGMDGRFLV---DDQGTLIIQSVTPEDAGNYSCQATNEVGTDEQTVT 603 Query: 1660 LKVYDKPS-KPEGPVIMREISRESVTIEWK----PP----LDDGGLELTKYAIEKHEPDN 1710 L + PS PV++ I E+V +E K PP GGLE+ I E + Sbjct: 604 LFYTEPPSVSALRPVVLAPIGEEAV-LECKASGVPPPRVIWYRGGLEM----ILAPEVAH 658 Query: 1711 NRWIKVADV-DRDVETYCIQKLNE 1733 +++ +V +RD Y + +NE Sbjct: 659 TGTLRIQEVQERDAGNYICKAVNE 682 Score = 59.7 bits (138), Expect = 9e-07 Identities = 77/309 (24%), Positives = 122/309 (39%), Gaps = 29/309 (9%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPI---VLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I N ++ G YT V N GEA VL + K+ P +K + + + Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVNST 2349 Query: 752 VILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 + L + P PTITW K+ + P L +DG + + P K D G Y A Sbjct: 2350 LSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADG---RLLQINPTKAWDSGRYLCVAT 2406 Query: 809 NSEGIAETSAVITVEEPT--EENAEP-PLFINRFQEITVK----------EKGTIKLVAR 855 N G + + V+ P ++ +P F QE ++ E L Sbjct: 2407 NVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCD 2466 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 P P +TWY++++ +S E I+ G + L I V SE D+G Y C ASN G+ Sbjct: 2467 TNAVPPPQLTWYKDDQPLSDIEGISV-LQGGRV-LQIPMVRSE-DAGRYTCKASNEVGED 2523 Query: 916 SHGARVTIDVEKVT--FVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971 + + V + L + TV L+CQ + T W N Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSS 2583 Query: 972 HREIIQEGR 980 + +++G+ Sbjct: 2584 KHQALEDGQ 2592 Score = 58.0 bits (134), Expect = 3e-06 Identities = 43/188 (22%), Positives = 70/188 (37%), Gaps = 8/188 (4%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXX 1539 P ++ +++ L CI G+P+P +TW +DG + + K T + Sbjct: 3639 PVIKGGHSDLSAAEGSQALLPCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGELLVKN 3698 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y CIA N G + I P T D+ H GD + G Sbjct: 3699 SERRDAGTYTCIAENAAGHTSRRVHLSILSLPTFTTLPGDLSLNH--GDRLWLRCTARGS 3756 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P + W N N+L + + ++ S ++ + R S YT A N G Sbjct: 3757 PTPHISWMVN-NRLVKE---GVLEQDGGSTLQRAAVTREDSGTYTCWAENIVGKVQAVSF 3812 Query: 1660 LKVYDKPS 1667 + V + P+ Sbjct: 3813 VHVKEAPA 3820 Score = 56.4 bits (130), Expect = 8e-06 Identities = 59/249 (23%), Positives = 99/249 (39%), Gaps = 27/249 (10%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I N + + R+ NEV + + E +K P E +K + + N + Sbjct: 2292 ILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISK-DDPLDEFSVKEVKAKVNSTL 2350 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 L C +P P +TWY+DG+ + + + Y C+A N G Sbjct: 2351 SLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGRLLQINPTKAWDSGRYLCVATNVAG 2410 Query: 1558 EVETSCVVGIQQKPV---ITISNEDIKQKHKVGDEWLVTAVIE----------------- 1597 E + V +Q P+ I NE + H+ +E L V+E Sbjct: 2411 EDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQ--EEELRGGVLEYREIVENNPAYLYCDTN 2468 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 +PPP++ WYK+ L +D E I+ + V++I ++ + +YT +ASN G + Sbjct: 2469 AVPPPQLTWYKDDQPL-SDIE-GISVLQGGRVLQIPMVRSEDAGRYTCKASNEVGEDWLH 2526 Query: 1658 VTLKVYDKP 1666 L V P Sbjct: 2527 YELLVLTPP 2535 Score = 55.6 bits (128), Expect = 1e-05 Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 +H G ++ C GYP P I+W I D + DD TL+I+ V PEDA Sbjct: 529 RHFSQGVELRISCTASGYPPPHISWRHNDQTI--GMDGRFLVDDQG--TLIIQSVTPEDA 584 Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLS 605 G ++C A N G T L P S Sbjct: 585 GNYSCQATNEVGTDEQTVTLFYTEPPS 611 Score = 52.8 bits (121), Expect = 1e-04 Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 6/174 (3%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 L C P PK+ W+R+G L+ T EN Y C+A N G Sbjct: 3247 LECPVEADPPPKIEWHREGVLLQADAHTLFLENGRFLQLQALDTSDSGDYNCVASNAAGS 3306 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 V I P I + V + L+ G+P V W K+G L Sbjct: 3307 TSLPFSVEIHMAPTIQPGPSVVNVS--VNETALLPCKTRGLPVSLVSWRKDGIPLVPGSP 3364 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + + +RI+ + S Y +ASN+AG+ L+V++ P+ GP Sbjct: 3365 RLEFLSDGS--LRIQPVYPQDSGYYLCQASNSAGSDRQGRELRVFEPPTIAPGP 3416 Score = 52.4 bits (120), Expect = 1e-04 Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 3/142 (2%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 L I + + +D Y C+ + T K VV+ PP I + GS L Sbjct: 3603 LRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPCIA 3662 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 Q P+P+ W + ++ + K +I S L +K E DAG Y EN GH Sbjct: 3663 QGIPEPHITWKKDGFVVPSMEG-KYTIQP-SGELLVKNSERRDAGTYTCIAENAAGHTSR 3720 Query: 1372 EMNVTILDKPSPPGKPNILEID 1393 ++++IL P+ P L ++ Sbjct: 3721 RVHLSILSLPTFTTLPGDLSLN 3742 Score = 51.6 bits (118), Expect = 2e-04 Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 3/78 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +GS C +G P P ITW ++ + PS + + Y L+++ DAGT+T Sbjct: 3652 EGSQALLPCIAQGIPEPHITW-KKDGFVVPSMEGK--YTIQPSGELLVKNSERRDAGTYT 3708 Query: 583 CVAKNAAGFASSTTELIV 600 C+A+NAAG S L + Sbjct: 3709 CIAENAAGHTSRRVHLSI 3726 Score = 48.4 bits (110), Expect = 0.002 Identities = 76/339 (22%), Positives = 124/339 (36%), Gaps = 51/339 (15%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI-----ITRLQNQKVNKGNKAT 1125 L I N D G Y+C++ +E A V +PP I + ++V +T Sbjct: 2290 LQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLDEFSVKEVKAKVNST 2349 Query: 1126 FEIELTKG---DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 +E + W+KDG + N + L DG+ L+I D+G Y C N Sbjct: 2350 LSLECESWAMPPPTITWYKDGQLVSPDNRLHLLADGR--LLQINPTKAWDSGRYLCVATN 2407 Query: 1183 -----SKCTAILT--------VEEPSINFTLR---------LPEFILVPANTDAYL---T 1217 K +L + +P+ F + + E+ + N AYL T Sbjct: 2408 VAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYREIVENNPAYLYCDT 2467 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 +P L TWYK + D E +++ R L I +D YTC + Sbjct: 2468 NAVPPPQL--TWYKDDQPLSDIEGISVLQG--GRVLQIPMVRSEDAGRYTCKASNEVGED 2523 Query: 1278 KLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKC 1331 L E++ P ++ + E + S V L P P W+ N I Sbjct: 2524 WLHYELLVLTPPVIQGDPEELVEEVTVNANSTVNLQCQALGTPTPVISWLRNGLPFIPSS 2583 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 KH +++ L + + D+ Y EN+ G ++ Sbjct: 2584 KH--QALEDGQV-LQVSVADAADSASYMCVAENSAGSSE 2619 Score = 47.6 bits (108), Expect = 0.004 Identities = 72/281 (25%), Positives = 111/281 (39%), Gaps = 37/281 (13%) Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE---EPSINFTLRLP 1203 + H +L++ G L+I + DAG Y+C V N A+ VE PSI+ L Sbjct: 2277 TKHYKLSVLGT-HGLQILNAQEQDAGRYTCVVTNEVGEAVKNYHVEVLIPPSISKDDPLD 2335 Query: 1204 EFIL--VPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 EF + V A ++ L++E + +TWYK ++ + L++D R L I Sbjct: 2336 EFSVKEVKAKVNSTLSLECESWAMPPPTITWYKDGQLVSPDNRLHLLAD--GRLLQINPT 2393 Query: 1259 TEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP---KIVD----YE------------REYR 1298 D Y CV + V V+ PP KI D +E EYR Sbjct: 2394 KAWDSGRYLCVATNVAGEDDKDFNVLVQVPPIFQKIGDPNEAFEVHHQEEELRGGVLEYR 2453 Query: 1299 -IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 I + L D A P P W + + + + S+ L I V + DAG Sbjct: 2454 EIVENNPAYLYCDTNAVPPPQLTWYKDDQPLSDIEGI--SVLQGGRVLQIPMVRSEDAGR 2511 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 Y + N G + + +L P G P L ++ ++N Sbjct: 2512 YTCKASNEVGEDWLHYELLVLTPPVIQGDPEEL-VEEVTVN 2551 Score = 46.8 bits (106), Expect = 0.007 Identities = 41/158 (25%), Positives = 63/158 (39%), Gaps = 11/158 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PTF+ P ++ G + L C P P I+W+ + E + +E D S Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLV--KEGV---LEQDGG---S 3781 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+ V + GTYT A N G+ + +K + P E ++ G+S Sbjct: 3782 TLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVK---EAPALQGEASSHLVELLGDSAR 3838 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 L G+P P I W K+ PV + K S+ I Sbjct: 3839 LDCAARGDPAPVIRWIKDGLPVLSSHHKHQLQNGSLAI 3876 Score = 45.2 bits (102), Expect = 0.020 Identities = 48/156 (30%), Positives = 62/156 (39%), Gaps = 16/156 (10%) Query: 452 NQDWWYVQKHLTEEKGWVPAQY--LMDENNYTQYLQKKLNE-KIDK-LPVFEKPTSEEQS 507 N WW L G + + L DE NYT E K D L V P E Sbjct: 1685 NLSWWKNGVSLVTTGGSLQIEKVDLRDEGNYTCVATNLAGEAKRDVVLKVLVPPNIE--- 1741 Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 P V K ++T + EC G P P+I+W+R I S+ M D V Sbjct: 1742 --PGLVNKAVLENT----SASLECLASGVPTPRISWYRGRQPIS-SKPGLMVSSDGRV-- 1792 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L I+ DAG++ CVA N AG + L + P Sbjct: 1793 LRIKRAQLSDAGSYRCVASNVAGSSELKFGLRINVP 1828 Score = 44.8 bits (101), Expect = 0.026 Identities = 52/233 (22%), Positives = 93/233 (39%), Gaps = 18/233 (7%) Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLT 1217 +L+I +DAG Y C N TA+ L V+ P + ++ L A L Sbjct: 3602 QLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPV---IKGGHSDLSAAEGSQALL 3658 Query: 1218 VEIPDETLD--VTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 I + +TW K V+ E K+T+ + L+++ D YTC+ +A Sbjct: 3659 PCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPSGE---LLVKNSERRDAGTYTCIAENAA 3715 Query: 1275 STTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 T +V + + P + + G + L + P P+ W+VN++++K+ Sbjct: 3716 GHTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGVL 3775 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + ++L V D+G Y EN G V + + P+ G+ Sbjct: 3776 EQDG----GSTLQRAAVTREDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGE 3824 Score = 43.6 bits (98), Expect = 0.061 Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 510 PIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P V LRP P G EC+ G P P++ W+R + + + + TL Sbjct: 609 PPSVSALRPVVLAPIGEEAVLECKASGVPPPRVIWYRG------GLEMILAPEVAHTGTL 662 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I+EV DAG + C A N G AS+ L V Sbjct: 663 RIQEVQERDAGNYICKAVNELGAASADIRLEV 694 Score = 41.9 bits (94), Expect = 0.19 Identities = 39/192 (20%), Positives = 72/192 (37%), Gaps = 10/192 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PPT + P + + L C P+P + W G+ + D + E+ + Sbjct: 3409 PPTIAPGPSNLTLTVHTQATLPCEARGSPKPHVVWKKNGQTLSLDRHQ----EAYRLLPS 3464 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S L +T+ + + N GE + + PP + + V + V Sbjct: 3465 SSLVLTDPDLQDTAQFECLVSNDAGETRRLFWVTVYV----PPTIADDRTDFTVTKMAPV 3520 Query: 753 ILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 +L+ G P P ++W K + K T ++ I + + G YT A N+ Sbjct: 3521 VLTCHTTGVPTPVVSWSKGGAQLGKRGSGYRVSPTGALEIEQALPI-HTGRYTCTARNAA 3579 Query: 812 GIAETSAVITVE 823 G+A ++ V+ Sbjct: 3580 GVAHKHVILMVQ 3591 Score = 41.5 bits (93), Expect = 0.25 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 6/81 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + C G P P I+W ++K + D +TL V ED+GT+TC Sbjct: 3744 GDRLWLRCTARGSPTPHISWMVNNRLVKEG-----VLEQDGGSTLQRAAVTREDSGTYTC 3798 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 A+N G + + + + EAP Sbjct: 3799 WAENIVGKVQAVSFVHVKEAP 3819 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/129 (19%), Positives = 46/129 (35%), Gaps = 1/129 (0%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541 PT +++ + + L C G P P ++W + + +K + Sbjct: 3730 PTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVKEGVLEQDGGSTLQRAAVT 3789 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C A N G+V+ V +++ P + +GD + G P Sbjct: 3790 REDSGTYTCWAENIVGKVQAVSFVHVKEAPALQ-GEASSHLVELLGDSARLDCAARGDPA 3848 Query: 1602 PEVIWYKNG 1610 P + W K+G Sbjct: 3849 PVIRWIKDG 3857 Score = 38.7 bits (86), Expect = 1.7 Identities = 59/275 (21%), Positives = 101/275 (36%), Gaps = 23/275 (8%) Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL 948 +L I+ +E D+G+Y C+A N +G + R+ + V V +K EG +L Sbjct: 3602 QLRISRASAE-DAGNYLCIAKNPSGTALGKTRLVVQVPPV--IKGGHSDLSAAEGSQALL 3658 Query: 949 EC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 C Q W + + M+ + IQ D G CI ++ Sbjct: 3659 PCIAQGIPEPHITWKKDGFVVPSMEGKYTIQPS--GELLVKNSERRDAGTYTCIAENAAG 3716 Query: 1007 STMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNK 1062 T V +I P F D + D L S T + W + ++K + Sbjct: 3717 HTSRRVHLSILSLPTFTTLPGDLSLNHGDRLWLRCTARGSPTPHISWMVNNRLVK--EGV 3774 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQNQKV 1118 + + +++ + D G Y+C I+ + V V E P + Sbjct: 3775 LEQDGGSTLQRAAVTR---EDSGTYTCWAENIVGKVQAVSFVHVKEAPALQGEASSHLVE 3831 Query: 1119 NKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNH 1151 G+ A + +GD ++RW KDG + S+H Sbjct: 3832 LLGDSARLDCA-ARGDPAPVIRWIKDGLPVLSSHH 3865 Score = 38.3 bits (85), Expect = 2.3 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 5/127 (3%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y C A N G + ++ + P I T + +VGD ++ + +P P + Sbjct: 2645 YTCEALNVAGRDQKLVLLSVFAPPTIKQTPGGQRDTTVVRVGDTAVLHCESDTLPEPVIT 2704 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 WYKNG ++ D++ + T + I ++ + Y+ + SN G ++ + + Sbjct: 2705 WYKNGQQIALDQQ--VQTLLDGQKLEIVNVQVADKGLYSCKVSNIVG-EAIRTFVLIVQV 2761 Query: 1666 PSKPEGP 1672 P E P Sbjct: 2762 PPIFENP 2768 Score = 37.9 bits (84), Expect = 3.0 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T CQV +TW R ++ S + + +L I + P D G + C Sbjct: 443 GETALLSCQVLDKAPYNLTWVRDWRVLPASPGRVVQLAN---LSLEISGIIPSDGGKYQC 499 Query: 584 VAKNAAGFASSTTELIVEAP 603 +A NA G ++ L++ P Sbjct: 500 LASNANGITRASVWLLIREP 519 Score = 36.3 bits (80), Expect = 9.2 Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +V ECQ + P P ++W + + P + D L + +D G +TC A Sbjct: 1939 SVTLECQSQAVPPPVLSWRKDGHALSPRPGVHLSADG---VLLQVERAEVQDVGRYTCEA 1995 Query: 586 KNAAGFASSTTELIVEAP 603 N AG + L V P Sbjct: 1996 LNKAGRSEKHYNLNVWVP 2013 Score = 36.3 bits (80), Expect = 9.2 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 8/116 (6%) Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129 +L I S D G Y CI ++ S TA VV++PP I + +G++A Sbjct: 3602 QLRISRASAEDAGNYLCIAKNPSGTALGKTRLVVQVPPVIKGGHSDLSAAEGSQALLPC- 3660 Query: 1130 LTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 + +G + + W KDG + S + TI +L + + + DAG Y+C N+ Sbjct: 3661 IAQGIPEPHITWKKDGFVVP-SMEGKYTIQ-PSGELLVKNSERRDAGTYTCIAENA 3714 >UniRef50_Q8N9C0 Cluster: Immunoglobulin superfamily member 22; n=9; Mammalia|Rep: Immunoglobulin superfamily member 22 - Homo sapiens (Human) Length = 903 Score = 186 bits (453), Expect = 6e-45 Identities = 167/786 (21%), Positives = 331/786 (42%), Gaps = 51/786 (6%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P+ +E + + +G+ + A+V GN +P I+W K +P K +I K Sbjct: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISW----KRESGIPIKESAKIFYDSINKE 122 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 +K E + + ++N + IA + + L + QE K K + Sbjct: 123 HVLKLEPLTSDDSDNYKCIASNDHADAIYTVS-------LLVTEGQE-----KMDFKKML 170 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 + P P + ++ + E + I + D E +Y + Sbjct: 171 KKRAPPAPK---KKQKKVANEKEML-------EILSKVPKKDFEKVCMEYGFTDFRGLLR 220 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEIS--- 968 + ++VE + +K L+ ET+ TV+ +C V W + + Sbjct: 221 KLKEMKKKVEVEAIRILKPLEDK-ETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQY 279 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV 1028 + ++ Q G D G+ V D+ S L V + +F+ +++ +V Sbjct: 280 SLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKV 339 Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF--EKRGHIRKLYIRNTSVHDEGE 1086 E+ A+ E+ ++ + + VW+ +G+ +K + +KY+ + G L I++ + D GE Sbjct: 340 TERQTAVFEIRLSKKEPNFVWKFNGKELK-RDDKYEITVSEDGLTHTLKIKDARLSDSGE 398 Query: 1087 YSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI 1146 +S + A++TV +P + ++ L+N +V + ++A E ELT D +RW KDG + Sbjct: 399 FSAEAGNLVQKAQLTVDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLL 458 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEY---SCEVGNSK---CTAILTVEEPSINFTL 1200 + +GK+ +L I D L D GEY + + G+ TAI+TVEE Sbjct: 459 MHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKS 518 Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 + + + + A L V + DE ++ W K I D ++ LI Sbjct: 519 GMSD-VHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGP 577 Query: 1261 DDQCEYTCVLLDAKSTTKLKV-EVVEFPPKIVDYEREYRI--KRGSDVTLLVDYQAFPQP 1317 + + +YT +S + + + P +++ + I K G + V ++ P P Sbjct: 578 EHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLP 637 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W + + + + A LTI D+G+ L+L+N+ G A +++++ Sbjct: 638 KVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSV 697 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435 L+ P +P + ++ ++ I W+ P G + ++ Y+VE ++ + W+ V I Sbjct: 698 LEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 757 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 T+ ++ L ++ Y FR AVN+ S + V+ + ++ P + + L +++ Sbjct: 758 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSS--SVVAKDPVKPPGLVQDL-HVSDSS 814 Query: 1496 NEDIEL 1501 N I L Sbjct: 815 NSSISL 820 Score = 109 bits (263), Expect = 6e-22 Identities = 139/666 (20%), Positives = 259/666 (38%), Gaps = 41/666 (6%) Query: 1218 VEIPDETLDVTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 +E+ D + + W K + K+ + K L+I +D Y+ + D + Sbjct: 257 MELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKR 316 Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + +L V ++ P K + + ++ + +PN W N K +K+ Sbjct: 317 MSAELTV--LDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFVWKFNGKELKRDDKY 373 Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 + ++ D + +L IK +D+G + N A + ++ + S + E Sbjct: 374 EITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTVDRIPIKFVSNLKNVRVKER 433 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEI-DTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 + + E E T + + + Q + T++ + + I++ + + + Sbjct: 434 SRACL-----ECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488 Query: 1452 RAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 A+ + D TEYY I + + TV+ + ++ EL C+ + Sbjct: 489 TVVAMQDGD------PTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAEL-CVVLNDEK 541 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQQ 1569 + W +DGK++ + ++ F G E+ V I Sbjct: 542 VEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFRAKG-TESEASVFIAD 600 Query: 1570 KPVITISNEDIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 P I S + H KVG + G P P+V WYK+G ++ ++ ++ E Sbjct: 601 PPTIDPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGE 660 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 +++ I R S ++ N G+++ + L V + P P + ++++E+VTI Sbjct: 661 DQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLEPPGFASQPQV-TDVTKEAVTI 719 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQ 1744 W P DGG + Y +E+ + +N W+ V + D T C + L E+ EY FRVIA Sbjct: 720 TWNAPTQDGGAPVLGYIVERRKKGSNLWVPV-NKDPIQGTKCTVDGLLEDTEYEFRVIAV 778 Query: 1745 NPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G + ++ S +V K + P N S+ + W E G P Y Sbjct: 779 NKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS-SNSSISLAW--REPAEGDPPSGYI 835 Query: 1804 VEIKQEG-KKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 +E++ E K+W + L Y FRI A NE G P D + Sbjct: 836 LEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGV--- 892 Query: 1861 KTLTPP 1866 + + PP Sbjct: 893 RAMPPP 898 Score = 109 bits (261), Expect = 1e-21 Identities = 183/872 (20%), Positives = 319/872 (36%), Gaps = 76/872 (8%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKD-GSEIQFSNHIQLTIDGKKQKL 1163 PE + + Q +G+KA F + +G+A + W ++ G I+ S I K+ L Sbjct: 67 PEFVEKPQPVTAPEGDKAVFRARV-QGNAKPHISWKRESGIPIKESAKIFYDSINKEHVL 125 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 K+ DD+ Y C N AI TV ++ + Sbjct: 126 KLEPLTSDDSDNYKCIASNDHADAIYTVS------------LLVTEGQEKMDFKKMLKKR 173 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-LKVE 1282 K+K V + E ++S V K+ + C E ++ +L K K ++VE Sbjct: 174 APPAPKKKQKKVANEKEMLEILSKVPKKDFE-KVCMEYGFTDFRGLLRKLKEMKKKVEVE 232 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVD-YQAFPQPNDE--WIVNSKIIKKCKHTKPSID 1339 + + D E + D T++ D PN + WI ++ ++ +++ D Sbjct: 233 AIRILKPLEDKETKV------DTTVVFDCIMELKDPNVKMIWIKGTEPLR-IQYSLGKYD 285 Query: 1340 SKSAS----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP---PGKP-NILE 1391 K L I V DAGIY L + G + +T+LD+P KP + E Sbjct: 286 VKQMGTKYMLVISNVNMNDAGIYSLSV----GDKRMSAELTVLDEPLKFLGEMKPVKVTE 341 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYR 1450 ++ I + E N + E + D E I+V T T I++ + + S Sbjct: 342 RQTAVFEIRLSKKEP--NFVWKFNGKELKRDDKYE-ITVSEDGLTHTLKIKDARLSDSGE 398 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 F A A N V + + K + LKN+ + L C Sbjct: 399 FSAEAGNLVQKAQLTVDRIPIKFVSN-----------LKNVRVKERSRACLECELTS-KD 446 Query: 1511 PKVTWYRDGKKLKTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVE--TSCV 1564 + W +DG+ L N R Y +A D E ++ + Sbjct: 447 VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAI 506 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 V ++++ + T+ + + H V+ E +W K+G ++ + I + Sbjct: 507 VTVEER-LATVKS-GMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPGMQIVKQ 564 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 + + H KYT A T +SV + PS E + T Sbjct: 565 GAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHT 624 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 K P L + + E + + + D I + + + Sbjct: 625 AHIKVPFRGKPLPKVTWYKDGMEVTEEERVSM-ERGEDQALLTISNCVREDSGLILLKLK 683 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N G + A + ++ P + E+V ITW ++GG+P++ Y V Sbjct: 684 NDHGSATA------TLHLSVLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 737 Query: 1805 EIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 E +++G W + + L +T Y+FR+ A N+ G P + Sbjct: 738 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 797 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 + PP ++ VS+S++ S++L W EP G P + YI+E + K W+K + S Sbjct: 798 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 855 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 + + + E+ + FRI A N GV P E Sbjct: 856 GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVE 887 Score = 93.5 bits (222), Expect = 6e-17 Identities = 117/524 (22%), Positives = 215/524 (41%), Gaps = 51/524 (9%) Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQV-VGNPRPTITWCKNNKPVKALPTKSDGD- 785 K E E ++++PL+ + +V+ + + +P + W K +P++ + D Sbjct: 227 KKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDV 286 Query: 786 ----THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 T + ++ + D G+Y+L S G SA +TV + EP F+ + Sbjct: 287 KQMGTKYMLVISNVNMNDAGIYSL----SVGDKRMSAELTVLD------EPLKFLGEMKP 336 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEI 899 + V E+ T R+++ P+ W N + + + IT + DG L I + Sbjct: 337 VKVTERQTAVFEIRLSKKE-PNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLS- 394 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST 958 DSG++ A N K A++T+D + FV +L K+ +E LEC+ TS V+ Sbjct: 395 DSGEFSAEAGNLVQK----AQLTVDRIPIKFVSNL-KNVRVKERSRACLECELTSKDVTL 449 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI-VKDQE-----TSTMLVV 1012 +W + + + + EG+ D G + ++D + ++ ++ V Sbjct: 450 RWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTV 509 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 +E + + D A L V +N E + VW +DG+ I K+G + Sbjct: 510 EERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLKDGKEITDLPG-MQIVKQGAVH 568 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP---PEIITRLQNQ--KVNKGNKATFE 1127 KL + EG+Y+ + A V + + P P ++ L V G+ A + Sbjct: 569 KLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTIDPSVLEALAAHAITVKVGHTAHIK 628 Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 + +G L V W+KDG E+ + + + L I +C +D+G ++ N Sbjct: 629 VPF-RGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG 687 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 +A T+ L P F P TD + E + +TW Sbjct: 688 SATATLHLS----VLEPPGFASQPQVTD------VTKEAVTITW 721 Score = 87.0 bits (206), Expect = 5e-15 Identities = 52/204 (25%), Positives = 87/204 (42%), Gaps = 2/204 (0%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 L PP V++ T +VT+ W P +GG+P+ YI+E + W + Sbjct: 698 LEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQG 757 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 + ++ + E E FR+ A N G P+ S + K P L + ++ Sbjct: 758 TKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNSS 817 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 + +W P G P GY + +R W + K+ ++ + + L E Y RI Sbjct: 818 ISLAWREPA--EGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIR 875 Query: 2043 ARNEIGLSEPLESDEPFKVIPGEG 2066 A NE G+ EP+E D+ + +P G Sbjct: 876 AVNEAGVGEPVELDKGVRAMPPPG 899 Score = 60.9 bits (141), Expect = 4e-07 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 18/327 (5%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ IP F K V E S LEC L + + + W G+ ++ S+ E Sbjct: 414 VDRIPIKFVSNLKNVRVKERSRACLECELTS-KDVTLRWKKDGQLLMHGTKYSMNHEGKR 472 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + L I + + G YTVVA+ ++G+ + I T E+ V + + Sbjct: 473 ----AELIIEDAQLSDGGEYTVVAM-QDGDPTEYYSTAIVTVEERLATVKSGMSDVHAAT 527 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTL 805 G L V+ + + W K+ K + LP G H + I + EG YT Sbjct: 528 GSPAELCV-VLNDEKVEGVWLKDGKEITDLPGMQIVKQGAVHKL-IFPSMGPEHEGKYTF 585 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A+ +E A +V + PT + + L ITVK T + P+P +T Sbjct: 586 RAKGTESEA---SVFIADPPTIDPSV--LEALAAHAITVKVGHTAHIKVPFRGKPLPKVT 640 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 WY++ ++ E ++ + L I+N E DSG N G ++ +++ + Sbjct: 641 WYKDGMEVTEEERVSMERGEDQALLTISNCVRE-DSGLILLKLKNDHGSATATLHLSV-L 698 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQT 952 E F Q + T+E T+ T Sbjct: 699 EPPGFASQPQVTDVTKEAVTITWNAPT 725 Score = 56.0 bits (129), Expect = 1e-05 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 2/107 (1%) Query: 1948 VSLPTESQSVRLEKHATVPSPP--TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005 + L + S H +V PP + ++ V V +W P DGGAP+LGY + Sbjct: 680 LKLKNDHGSATATLHLSVLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVER 739 Query: 2006 RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 R +W+ V K + K + L E+ Y R+ A N+ G +P Sbjct: 740 RKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQP 786 Score = 53.2 bits (122), Expect = 8e-05 Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 4/93 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVA-T 567 P FVEK +P P+G F +V+G +P I+W R++ I IK S +++YD N Sbjct: 67 PEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESA--KIFYDSINKEHV 124 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + + +D+ + C+A N A T L+V Sbjct: 125 LKLEPLTSDDSDNYKCIASNDHADAIYTVSLLV 157 Score = 52.0 bits (119), Expect = 2e-04 Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 7/158 (4%) Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 S TH T + K+ E V K S I E +++T P F+ + Q Sbjct: 19 SSSTTHVQTFSQTTKIVGEEVVRRK---SSSIVEFFSLVTRSSNIPAGDSVPEFVEKPQP 75 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSETITQNFDGENIELVITNVDSEID 900 +T E ARV N P I+W R + I I S I + + L + + S+ D Sbjct: 76 VTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSD-D 134 Query: 901 SGDYKCVASNSAGKSSH--GARVTIDVEKVTFVKHLQK 936 S +YKC+ASN + + VT EK+ F K L+K Sbjct: 135 SDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKK 172 Score = 45.6 bits (103), Expect = 0.015 Identities = 45/196 (22%), Positives = 86/196 (43%), Gaps = 15/196 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F + K V E + E RL + EP+ W F G+E+ D+ + + D + Sbjct: 327 PLKFLGEMKPVKVTERQTAVFEIRL-SKKEPNFVWKFNGKELKRDDKYEITVSEDGLTH- 384 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 LKI + + G ++ A N +A L T ++ P + + LK++ V++ Sbjct: 385 -TLKIKDARLSDSGEFSAEAGNLVQKAQL-------TVDRIPIKFVSNLKNVRVKERSRA 436 Query: 753 ILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 L ++ T+ W K+ + + + + + I++ ++ D G YT+ A Sbjct: 437 CLECELTSKD-VTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQD 495 Query: 811 EGIAE--TSAVITVEE 824 E ++A++TVEE Sbjct: 496 GDPTEYYSTAIVTVEE 511 Score = 39.5 bits (88), Expect = 0.99 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T + G P P++TW++ + + M +D A L I ED+G Sbjct: 622 GHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQ-ALLTISNCVREDSGLILL 680 Query: 584 VAKNAAGFASSTTELIVEAP 603 KN G A++T L V P Sbjct: 681 KLKNDHGSATATLHLSVLEP 700 Score = 38.7 bits (86), Expect = 1.7 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 5/117 (4%) Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEI-IKPK-KNKY 1063 S+ + +++PEF+ K Q E D A+ + + W+R+ I IK K Y Sbjct: 57 SSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRESGIPIKESAKIFY 116 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 D + H+ KL + D Y CI ++ A TV L E ++ +K+ K Sbjct: 117 DSINKEHVLKL--EPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLK 171 >UniRef50_UPI0000F33BB2 Cluster: Connectin; n=1; Bos taurus|Rep: Connectin - Bos Taurus Length = 473 Score = 185 bits (450), Expect = 1e-44 Identities = 111/365 (30%), Positives = 179/365 (49%), Gaps = 13/365 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLEN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 I+G P PEV W K+ L+N + E I + + + + +K+ R S Y ++A N AG Sbjct: 114 IKGRPAPEVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSYILKAKNVAGE 173 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 SV V +KV D+P PEGP+++ ++ E T+ WKPPL DGG ++ Y +E+ E W Sbjct: 174 KSVTVNVKVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW 233 Query: 1714 IKVADVDRDVETY-C-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 VD +V+T C K+ + EY+FRV A N G +ALES P++ + A +P Sbjct: 234 ---TVVDANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHPVIARFA-SLPD-AP 288 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW---KXXXXXXXXXARIQ 1827 + +V + W +GGS ++ Y +E K ++ +W ++ Sbjct: 289 GRPEVTDVTRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTRVNKDHVVYDTRLKVT 348 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 L YQFR+ A N G S P + + I+ + P P + + + +TL W Sbjct: 349 GLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPETLQIFDVSREGMTLTWY 408 Query: 1888 EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 PE +GGS +T YI+E K V+ W ++ V ++ + + E E R++A N G Sbjct: 409 PPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAVNVRG 468 Query: 1948 VSLPT 1952 P+ Sbjct: 469 TGKPS 473 Score = 122 bits (293), Expect = 1e-25 Identities = 121/485 (24%), Positives = 206/485 (42%), Gaps = 25/485 (5%) Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 +DI + K + VT EGI W KNG ++++ + TK+ T + I+ + Sbjct: 3 KDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHF 59 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE-ISRESVTIEWKPPLDDGG- 1695 +++YT A T+++ V ++ P + R + R ++I P+ Sbjct: 60 GDAAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPA 119 Query: 1696 --LELTKYAIE-KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 + TK I K+ + IK D + +++ Y+ + A+N G Sbjct: 120 PEVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSG-SYILK--AKNVAG---- 172 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812 E V LD P + E + W P ++GGS II+Y VE ++ + Sbjct: 173 -EKSVTVNVKVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRL 231 Query: 1813 -WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 W + K+ Y FR+ A N+ G S I + + P P Sbjct: 232 VWTVVDANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHP--VIARFASLPDAPG 289 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-- 1928 V++ T +V+L W+ P +GGS + YIIE K K WT+ V V++ ++ Sbjct: 290 RPEVTDVTRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTR-VNKDHVVYDTRLKVT 348 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQS-VRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 + E + FR++A N G S P+E+ + + + + +P PP L+I V + +W Sbjct: 349 GLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPET-LQIFDVSREGMTLTW 407 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 PE DGG+ + GY + ++V W+ V KV V ++ L E Y R+ A N Sbjct: 408 YPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLIEGLEYEHRVTAVNVR 467 Query: 2048 GLSEP 2052 G +P Sbjct: 468 GTGKP 472 Score = 103 bits (247), Expect = 5e-20 Identities = 73/258 (28%), Positives = 113/258 (43%), Gaps = 8/258 (3%) Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 V + E + W K I+ T++ + + +L IR D EYT V A ST Sbjct: 17 VTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGDAAEYTFVAGKATSTA 76 Query: 1278 KLKVEVV-EFPPKI---VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 L VEV E P + R ++ G + + V + P P W ++ +K + Sbjct: 77 TLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN 136 Query: 1334 TKPSIDSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + I S + SL++K D+G Y L+ +N G V +NV +LD+P PP P ++ Sbjct: 137 IENKIKSTDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKVLDRPGPPEGPIVIS 196 Query: 1392 -IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSY 1449 + + + W P G S II Y+VE +E W V N+ + + Y Sbjct: 197 GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLGCKTTKIIKGNEY 256 Query: 1450 RFRAYAVNEVDISDASET 1467 FR AVN+ I DA E+ Sbjct: 257 IFRVRAVNKYGIGDALES 274 Score = 77.4 bits (182), Expect = 4e-12 Identities = 84/405 (20%), Positives = 162/405 (40%), Gaps = 28/405 (6%) Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 L++ + + TFE+ + +W K+G EI+ ++ Q+ L I + D Sbjct: 2 LKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKSTDRCQMRTKKLTHSLNIRNVHFGD 61 Query: 1173 AGEYSCEVGNSKCTAILTVE-----EPSINFTLRLPEFILVPANTDAYLTVEIPDETL-D 1226 A EY+ G + TA L VE P L ++V A + V I + Sbjct: 62 AAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPE 121 Query: 1227 VTWYKKKSVIEDTEKFT--LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 VTW K +++ + S +L ++ D Y +L AK+ K V Sbjct: 122 VTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSY---ILKAKNVAGEKSVTV 178 Query: 1285 EFPPKIVDY----EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK--CKHTKPSI 1338 K++D E I + + ++ Q I+N + ++ + + Sbjct: 179 NV--KVLDRPGPPEGPIVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVV 236 Query: 1339 DSKSASLTIK--KVENTDAGIYKLRLENNCGHADVEMNVTILDK----PSPPGKPNILEI 1392 D+ +L K K+ + I+++R N G D + ++ + P PG+P + ++ Sbjct: 237 DANVQTLGCKTTKIIKGNEYIFRVRAVNKYGIGDALESHPVIARFASLPDAPGRPEVTDV 296 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSY 1449 S++++ W P G S ++ Y++E + + W V + T+ + L Y Sbjct: 297 TRSTVSLIWSAPVYDGGSKVVGYIIERKPKKSLRWTRVNKDHVVYDTRLKVTGLMEGCDY 356 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 +FR AVN S+ SE + + + + I P + +++ E Sbjct: 357 QFRVTAVNAAGNSEPSEASNFISCREPSYIPGPPETLQIFDVSRE 401 Score = 48.4 bits (110), Expect = 0.002 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 P PP I ++ + + W PE+ G S + Y+VE +E+ W+ V + T T Sbjct: 387 PGPPETLQIFDVSREGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRY 446 Query: 1441 QN--LKTNSSYRFRAYAVN 1457 ++ L Y R AVN Sbjct: 447 RSTGLIEGLEYEHRVTAVN 465 Score = 46.8 bits (106), Expect = 0.007 Identities = 45/165 (27%), Positives = 71/165 (43%), Gaps = 19/165 (11%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 WL G EI + + + H L I NV YT VA G+A+ L Sbjct: 28 WLKNGVEIKSTDRCQMRTKKLTHS----LNIRNVHFGDAAEYTFVA----GKATSTATLY 79 Query: 727 IKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT--- 780 ++ + P E ++++VR G S+ + + G P P +TW K+N +K Sbjct: 80 VEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIEN 139 Query: 781 --KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 KS S+++ ++ D G Y LKA+N G E S + V+ Sbjct: 140 KIKSTDFATSLSVKDAIRI-DSGSYILKAKNVAG--EKSVTVNVK 181 Score = 42.7 bits (96), Expect = 0.11 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 9/160 (5%) Query: 768 WCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W KN +K+ ++ THS+ I + D YT A G A ++A + VE Sbjct: 28 WLKNGVEIKSTDRCQMRTKKLTHSLNI-RNVHFGDAAEYTFVA----GKATSTATLYVEV 82 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 E + L + + V+ +I++ + P P +TW ++N + I Sbjct: 83 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENKIK 142 Query: 885 GENIELVITNVDS-EIDSGDYKCVASNSAGKSSHGARVTI 923 + ++ D+ IDSG Y A N AG+ S V + Sbjct: 143 STDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKV 182 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Query: 505 EQSMAPIF---VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 E+ MAP F E R G +++ ++G P P++TW + +K + + Sbjct: 83 EREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENKIK 142 Query: 562 DDNVAT-LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + AT L +++ D+G++ AKN AG S T + V Sbjct: 143 STDFATSLSVKDAIRIDSGSYILKAKNVAGEKSVTVNVKV 182 Score = 39.5 bits (88), Expect = 0.99 Identities = 42/169 (24%), Positives = 66/169 (39%), Gaps = 10/169 (5%) Query: 1023 LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 L+D +EKD EV +N E W ++G IK ++ + L IRN Sbjct: 2 LKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIK-STDRCQMRTKKLTHSLNIRNVHFG 60 Query: 1083 DEGEYSCILRDESCTAEVTVV---ELPP--EIITRLQNQKVNKGNKATFEIELTKGDAL- 1136 D EY+ + + TA + V E+ P E+ L+ V + + KG Sbjct: 61 DAAEYTFVAGKATSTATLYVEVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAP 120 Query: 1137 -VRWFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGN 1182 V W KD ++ +I+ I L + D D+G Y + N Sbjct: 121 EVTWTKDNINLKNRANIENKIKSTDFATSLSVKDAIRIDSGSYILKAKN 169 >UniRef50_UPI000065EC1F Cluster: Homolog of Homo sapiens "Obscurin.; n=2; Euteleostomi|Rep: Homolog of Homo sapiens "Obscurin. - Takifugu rubripes Length = 1954 Score = 184 bits (447), Expect = 3e-44 Identities = 147/595 (24%), Positives = 267/595 (44%), Gaps = 35/595 (5%) Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKSMIVRQGES 751 +L +TN+KK EG Y+ N AS+ K P Q+ + L ++ +G+ Sbjct: 1299 ILTVTNMKKEDEGEYSCECRNDRTSASV--------SSKAPRQIRLMAKLNNVAAMEGKD 1350 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 I V ++ W + PV + T+ G++H++TI +D G + +AE Sbjct: 1351 AIFKCAVTPADA-SVRWFHKSVPVTSGLKYKTEHSGNSHTLTITSVTH-EDAGEISFEAE 1408 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 A + V+ EP +F + + +TV+E+ KL +++ P + W + Sbjct: 1409 GKS----CKANLQVQH------EPVMFKKKLENVTVEEQSEAKLEVELSK-PSDEVRWMK 1457 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N+ +I P+ + DG LV+ +V ++ D G Y C + + G ++ ++++K+ Sbjct: 1458 NSVVIQPTGNLKICVDGAKQALVLKSV-TQADRGIYSC---ETLDDKTQG-KLNVEMKKI 1512 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 +K L ++ E +TV LE + S V W + ++ + I G+ Sbjct: 1513 QVIKGLTET-TAHETETVTLEVELSQADVDGSWTKDGIKVKSGGNSRITVLGKKHALTLS 1571 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G + + S L+V E + + D V EK+ E E++ +V Sbjct: 1572 NLKMEDAGNVVFQAEGVRVSGRLIVLEPPAMISKPIMDISVPEKEKVTFECEVSRTNTEV 1631 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W +D +KP K + G R L I S D G Y C D++ +A+++V Sbjct: 1632 KWFKDNVELKPGK-MFSIHSLGRKRTLVISKCSPEDAGTYICRTPDDNTSAKLSVHARDI 1690 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 I+ +LQ+ +V + ATF E++ D +WFK ++++ S++I++ +G+ L Sbjct: 1691 RIVKKLQDVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFRS 1750 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 +D GE + +A L V+E + F +L + I + + +L ++ + V Sbjct: 1751 VTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKHR-GHLECQVSRASAKV 1809 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 WYK K+ I+ K+ + S+ R L I E D+ YTC D K++ KL VE Sbjct: 1810 KWYKSKTEIKPGLKYEIQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVE 1864 Score = 158 bits (383), Expect = 2e-36 Identities = 182/871 (20%), Positives = 347/871 (39%), Gaps = 59/871 (6%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L C V+ P+ ++ W G+ + + + + + + L I + K G YT A Sbjct: 1083 LSCE-VSDPKVEVKWYKDGKLLTSTKAVHMESKGKIRE----LVIEKMDKKDAGEYTCEA 1137 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 G L L++ T E Q ++ VR E+++L+ ++ ++ W ++ Sbjct: 1138 ----GAEKLLFKLQM-TDEAVKFQKKAVNETCAVRASENIVLTTELTAE-NGSVKWFRDG 1191 Query: 773 ---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 K K + DG + ++ I+K + KD G Y+ + A+ V+ + Sbjct: 1192 VELKESKKYEMRKDGFSRTL-IVKSTETKDSGSYSCQT------AQDKLEFKVQVKGMLH 1244 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 EP K G+ + + VP + + G Sbjct: 1245 TEPVHNTKIVGRCLPKTSGSDFISDAALKFVVPL-----KAATVELEGRYSVTTSGPQRI 1299 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 L +TN+ E D G+Y C N +S ++ + + + ++ EGK I + Sbjct: 1300 LTVTNMKKE-DEGEYSCECRNDRTSASVSSKAPRQIRLMAKLNNVAAM----EGKDAIFK 1354 Query: 950 CQ-TSHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETS 1007 C T S +W+H + SG+ ++ G D G I + + Sbjct: 1355 CAVTPADASVRWFHKSVPVTSGLKYKTE-HSGNSHTLTITSVTHEDAGEISFEAEGKSCK 1413 Query: 1008 TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK 1067 L V+ F +KL++ V+E+ A LEVE++ + +V W ++ +I+P N Sbjct: 1414 ANLQVQHEPVMFKKKLENVTVEEQSEAKLEVELSKPSDEVRWMKNSVVIQPTGN-LKICV 1472 Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127 G + L +++ + D G YSC D+ ++ V ++I L ++ T E Sbjct: 1473 DGAKQALVLKSVTQADRGIYSCETLDDKTQGKLNVEMKKIQVIKGLTETTAHETETVTLE 1532 Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 +EL++ D W KDG +++ + ++T+ GKK L + + ++DAG + + + Sbjct: 1533 VELSQADVDGSWTKDGIKVKSGGNSRITVLGKKHALTLSNLKMEDAGNVVFQAEGVRVSG 1592 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247 L V EP + + + I VP E+ +V W+K ++ + F++ S Sbjct: 1593 RLIVLEPPAMISKPIMD-ISVPEKEKVTFECEVSRTNTEVKWFKDNVELKPGKMFSIHSL 1651 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +KRTL+I KC+ +D Y C D ++ KL V + +IV ++ + T Sbjct: 1652 GRKRTLVISKCSPEDAGTYICRTPDDNTSAKLSVHARDI--RIVKKLQDVEVMEKESATF 1709 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + + + + +W S +K + K + ++ L + V D G K E C Sbjct: 1710 VCEI-SHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFRSVTPEDMGEIKFTAEKACS 1768 Query: 1368 HADV---EMNVTIL----DKPSPPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVE 1418 A + E+ V + DK + LE + +S + W + + + Y E Sbjct: 1769 SAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRASAKVKWYKSKTEIKPGLKY---E 1825 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNL-----KTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 Q D +++ N+ + KT+ +++ V E TE + Sbjct: 1826 IQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVEEQSISIVRELSPVEVTEPFAA 1885 Query: 1474 IKETKIQSPTVEKP---LKNITTEPNEDIEL 1501 + E +I V+ P L + + + DIE+ Sbjct: 1886 VFEVEISMELVKPPVWTLNGVAVQESRDIEM 1916 Score = 150 bits (363), Expect = 5e-34 Identities = 141/568 (24%), Positives = 246/568 (43%), Gaps = 43/568 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F KK + V+E S+ LE L + P ++ W+ I P N+ + ++ Sbjct: 1422 PVMFKKKLENVTVEEQSEAKLEVEL-SKPSDEVRWMKNSVVIQPTGNLKICVDGAKQ--- 1477 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L + +V + G Y+ ++ + + L + +K QVI+ L + E+V Sbjct: 1478 -ALVLKSVTQADRGIYSCETLDDKTQGKLNVEMK-------KIQVIKGLTETTAHETETV 1529 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSD---GDTHSITILKPKKVKDEGVYTLKAEN 809 L ++ +W K+ VK+ G H++T L K++D G +AE Sbjct: 1530 TLEVEL-SQADVDGSWTKDGIKVKSGGNSRITVLGKKHALT-LSNLKMEDAGNVVFQAE- 1586 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G+ + +I +E PP I++ +I+V EK + V+R + W++ Sbjct: 1587 --GVRVSGRLIVLE--------PPAMISKPIMDISVPEKEKVTFECEVSRTNT-EVKWFK 1635 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 +N + P + + + G LVI+ E D+G Y C + + A++++ + Sbjct: 1636 DNVELKPGKMFSIHSLGRKRTLVISKCSPE-DAGTYICRTPDD----NTSAKLSVHARDI 1690 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 VK LQ E E ++ C+ SH V +W+ ++ D+ ++ QEGR Sbjct: 1691 RIVKKLQ-DVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDNIKMRQEGRTYVLLFR 1749 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D+G IK + +S L VKE +F++KL+D K LE +++ +A V Sbjct: 1750 SVTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRASAKV 1809 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP 1107 W + IKP KY+ + RKL I N DE Y+C D+ + ++ V E Sbjct: 1810 KWYKSKTEIKPGL-KYEIQSEDVYRKLTINNVDEADEDTYTCDATDDKTSCKLLVEEQSI 1868 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVR---WFKDGSEIQFSNHIQLTIDGKKQKLK 1164 I+ L +V + A FE+E++ LV+ W +G +Q S I++ +G +L Sbjct: 1869 SIVRELSPVEVTEPFAAVFEVEISM--ELVKPPVWTLNGVAVQESRDIEMEKEGTLHRLT 1926 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 G G SK +A L V+ Sbjct: 1927 FKKTKASMTGSVQFTAGKSKSSAQLAVK 1954 Score = 143 bits (346), Expect = 5e-32 Identities = 156/742 (21%), Positives = 301/742 (40%), Gaps = 49/742 (6%) Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 +L C VA P+ ++ W G ++ + + VA + L + +V+K G Y+ Sbjct: 706 VLSCD-VADPKTEVKWCKDGRQLASTKTVRVASKGKNRQ----LVLDSVEKKDAGEYSCE 760 Query: 712 AVNREGEASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 + L + +++K+ V + +K+ + + V LS +V + + + W K Sbjct: 761 VGTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKATV---SQKVTLSCEV-SDSKTEVKWYK 816 Query: 771 NNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 + K + KA+ +S G + + I K KD G Y A G + + I +E Sbjct: 817 DGKLLTSSKAIHAESKGRSRLLVIESVDK-KDAGEYMCDA----GTEKLAFKIHMEAARA 871 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT---WYRNNEIISPSETITQNFD 884 E P F+N+ + + + K + A ++ V + T WY++ + +SPS + + Sbjct: 872 EVQAKPAFLNK-EAVQREVKAVLSQKATLSCEVVDNATEVKWYKDGKQLSPSRAVQVDSK 930 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF--VKHLQKSYETEE 942 G+ +LVI NV+ + D+G+Y C G +V + K F + +QK + Sbjct: 931 GKIRQLVICNVEKK-DAGEYTC----EVGTEKLAFKVQVAEIKSAFSNKESVQKDVKATV 985 Query: 943 GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 + L C+ S KWY + K ++ I +G+ D G C Sbjct: 986 SQKATLACEVSDAKTEVKWYKDGKLLTSTKTLHIESKGKSRQLVVDSVEKKDSGEYICEA 1045 Query: 1002 KDQETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058 ++ + L V E F K ++ + A L E++ +V W +DG+++ Sbjct: 1046 GTEKLAFRLHVAEAAVGFSNKESVKKEVKAALSQKATLSCEVSDPKVEVKWYKDGKLLTS 1105 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-- 1116 K + E +G IR+L I D GEY+C E ++ + + + + N+ Sbjct: 1106 TKAVH-MESKGKIRELVIEKMDKKDAGEYTCEAGAEKLLFKLQMTDEAVKFQKKAVNETC 1164 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V ELT + V+WF+DG E++ S ++ DG + L + + D+G Y Sbjct: 1165 AVRASENIVLTTELTAENGSVKWFRDGVELKESKKYEMRKDGFSRTLIVKSTETKDSGSY 1224 Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFI--LVPANTDAYLTVEIPDETLDVTWYKKKS 1234 SC+ K + V+ + + + +P + + I D L K + Sbjct: 1225 SCQTAQDKLEFKVQVKGMLHTEPVHNTKIVGRCLPKTSGSDF---ISDAALKFVVPLKAA 1281 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE 1294 +E ++++ + +R L + ++D+ EY+C + +++ + + +++ Sbjct: 1282 TVELEGRYSVTTSGPQRILTVTNMKKEDEGEYSCECRNDRTSASVSSKAPR-QIRLMAKL 1340 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPND---EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 G D ++ P D W S + K S +LTI V Sbjct: 1341 NNVAAMEGKDAI----FKCAVTPADASVRWFHKSVPVTSGLKYKTEHSGNSHTLTITSVT 1396 Query: 1352 NTDAGIYKLRLENNCGHADVEM 1373 + DAG E A++++ Sbjct: 1397 HEDAGEISFEAEGKSCKANLQV 1418 Score = 137 bits (331), Expect = 4e-30 Identities = 135/500 (27%), Positives = 211/500 (42%), Gaps = 60/500 (12%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P+ + K+ V G+ LS VVG+P P ITW K+ + + DGD + +TI Sbjct: 7 PRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGDVYRLTI 66 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 + ++D G Y +A+N+ G A + + V PTE P+F+ + V G + Sbjct: 67 YE-LTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDVA 125 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 V RV +P + W ++ + S + D + L I +V +D G Y C A N+ Sbjct: 126 FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSV-RNLDGGTYTCRAQNT 184 Query: 912 AGKSSHGARVTIDV---------EKVTFVKHLQKS----------YETEE---------- 942 G++ A +T+D + + + HLQK Y +EE Sbjct: 185 VGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEESSITSSTVTS 244 Query: 943 ---GKTVILEC-QTSH-TVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGV 996 GK L C T H W + IS G H + D G+ Sbjct: 245 VTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVIYEDQAENFILKILYCKQTDNGL 304 Query: 997 IKC---IVKDQETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 C + Q S +LV VKE F RKLQD EV+EK A+L E+ W + Sbjct: 305 YTCNAGNMAGQTYSAVLVTVKEPQVPFRRKLQDVEVQEKKSAMLLCEVPLVATQTNWFME 364 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT-AEVTVVELPPEIIT 1111 E + +KY E+ G +R+L I N + +D+G Y C +++ S T AE+TV Sbjct: 365 -ETRLEQSSKYYMEQEGTLRRLTIHNVTTNDDGVYICEMKEGSRTVAELTV--------- 414 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 VN + F +EL W ++G +++ + I + ++ L I DC D Sbjct: 415 ---RGMVN--DTVIFCVELEHPCVDAYWTRNGEKLKEDSRISIACSLRQYTLTIRDCQAD 469 Query: 1172 DAGEYSCEVGNSKCTAILTV 1191 D+GE + G+ K + V Sbjct: 470 DSGEVAFVAGDCKTSTRFAV 489 Score = 130 bits (314), Expect = 4e-28 Identities = 157/735 (21%), Positives = 276/735 (37%), Gaps = 45/735 (6%) Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 +D ++ C + P D W GE++ D IS+A + Y L I + + G Sbjct: 419 NDTVIFCVELEHPCVDAYWTRNGEKLKEDSRISIACS--LRQY--TLTIRDCQADDSGEV 474 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL---SAQVVGNPRPT 765 VA G+ + K PP P+ ++ + ES I S P P Sbjct: 475 AFVA----GDCKTSTRFAVTAARKHPPD--PPVDAVTHNKTESSITIQWSPPDSDRPVPI 528 Query: 766 ITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 + + V K + G+T + T + +E Y + ++ + E Sbjct: 529 KGYIVERRKVGNKTWQRCNPGETITSTEITICSFTEEASYQFRISAMNDFGQSPYL---E 585 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P EP + + + G + V + V S W N ++ Sbjct: 586 VPGSFYLEPLAEVTKGLINSTALAGR-EFSISVELSAVCSGFWSLNGRLLRSGADYLITR 644 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH-LQKSYETEE 942 L+I V +++D K V S + + + F K +Q + Sbjct: 645 SKSTHTLLIHCVTADMDGTVVKFVGGGSQSSCVLSVK---EAQSAFFKKESVQNDVKATV 701 Query: 943 GKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 + +L C + KW + ++++ + +G+ D G C V Sbjct: 702 SQKAVLSCDVADPKTEVKWCKDGRQLASTKTVRVASKGKNRQLVLDSVEKKDAGEYSCEV 761 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVEINSETADVVWERDGEII 1056 ++ L V + + +D KE + L E++ +V W +DG+++ Sbjct: 762 GTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKATVSQKVTLSCEVSDSKTEVKWYKDGKLL 821 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV------VELPPEII 1110 K + E +G R L I + D GEY C E ++ + V+ P + Sbjct: 822 TSSKAIHA-ESKGRSRLLVIESVDKKDAGEYMCDAGTEKLAFKIHMEAARAEVQAKPAFL 880 Query: 1111 TRLQNQKVNKG---NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 + Q+ K KAT E+ V+W+KDG ++ S +Q+ GK ++L I + Sbjct: 881 NKEAVQREVKAVLSQKATLSCEVVDNATEVKWYKDGKQLSPSRAVQVDSKGKIRQLVICN 940 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETL 1225 + DAGEY+CEVG K + V E F+ + + + + + A L E+ D Sbjct: 941 VEKKDAGEYTCEVGTEKLAFKVQVAEIKSAFSNKESVQKDVKATVSQKATLACEVSDAKT 1000 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EV 1283 +V WYK ++ T+ + S K R L++ + D EY C K +L V Sbjct: 1001 EVKWYKDGKLLTSTKTLHIESKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHVAEAA 1060 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 V F K ++E + TL + + P+ +W + K++ K K Sbjct: 1061 VGFSNK-ESVKKEVKAALSQKATLSCEV-SDPKVEVKWYKDGKLLTSTKAVHMESKGKIR 1118 Query: 1344 SLTIKKVENTDAGIY 1358 L I+K++ DAG Y Sbjct: 1119 ELVIEKMDKKDAGEY 1133 Score = 126 bits (305), Expect = 5e-27 Identities = 274/1304 (21%), Positives = 485/1304 (37%), Gaps = 143/1304 (10%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+ + + G C V G P P ITW + + F+ D D V L Sbjct: 7 PRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGD-VYRLT 65 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I E+ ED+G + C AKN G A + L V P +EM Sbjct: 66 IYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALP-----TEMPHRA-------------- 106 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW----LFKGE----EIVPDENIS 681 P F KP + V G D+ CR+ A PE + W + GE +IV D + S Sbjct: 107 ----PVFVVKPASTRVGLGGDVAFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGS 162 Query: 682 -VAIES----DMHMYCSVLKITNVKKFQEGTYTVVA------VNREGEASLPIVLKIKTG 730 + I+S D Y + T + TV A + + + L + K K Sbjct: 163 TLKIQSVRNLDGGTYTCRAQNTVGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEE 222 Query: 731 EKEPPQVIEPLKSMI-------VRQGESVILSAQVVGNPRPTITWCKNNKPV----KALP 779 K+ + +S I V G+ LS V G+P+P ITW K+ + + + Sbjct: 223 MKKDISIYRSEESSITSSTVTSVTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVI 282 Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839 + + + IL K+ D G+YT A N G ++ ++TV+EP + P F + Sbjct: 283 YEDQAENFILKILYCKQT-DNGLYTCNAGNMAGQTYSAVLVTVKEP-----QVP-FRRKL 335 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 Q++ V+EK + L+ V + W+ + S +G L I NV + Sbjct: 336 QDVEVQEKKSAMLLCEVPLVATQT-NWFMEETRLEQSSKYYMEQEGTLRRLTIHNVTTN- 393 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VST 958 D G Y C + G+R ++ V TVI + H V Sbjct: 394 DDGVYIC-------EMKEGSRTVAELTVRGMVND-----------TVIFCVELEHPCVDA 435 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018 W N +++ I R D G + + D +TST V Sbjct: 436 YWTRNGEKLKEDSRISIACSLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFAVTAARKH 495 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK--NK-YDFEKRGH-IRKL 1074 D K + + ++ + +D G I++ +K NK + G I Sbjct: 496 PPDPPVDAVTHNKTESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPGETITST 555 Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELP--------PEIITRLQNQKVNKGNKATF 1126 I S +E Y + + + +E+P E+ L N G + + Sbjct: 556 EITICSFTEEASYQFRISAMNDFGQSPYLEVPGSFYLEPLAEVTKGLINSTALAGREFSI 615 Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-SKC 1185 +EL+ + W +G ++ +T L I+ D G VG S+ Sbjct: 616 SVELSAVCSGF-WSLNGRLLRSGADYLITRSKSTHTLLIHCVTADMDGTVVKFVGGGSQS 674 Query: 1186 TAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 + +L+V+E F + + + + A L+ ++ D +V W K + T+ Sbjct: 675 SCVLSVKEAQSAFFKKESVQNDVKATVSQKAVLSCDVADPKTEVKWCKDGRQLASTKTVR 734 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD---YEREYRIK 1300 + S K R L++ + D EY+C + K KL V ++ + ++E + Sbjct: 735 VASKGKNRQLVLDSVEKKDAGEYSCEVGTEKLLFKLHVTDIQVKSAFSNKDSVQKEIKAT 794 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY-- 1358 VTL + + +W + K++ K +S L I+ V+ DAG Y Sbjct: 795 VSQKVTLSCEVSD-SKTEVKWYKDGKLLTSSKAIHAESKGRSRLLVIESVDKKDAGEYMC 853 Query: 1359 -----KL--RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 KL ++ A+V+ L+K + + + ++++ C E N+T Sbjct: 854 DAGTEKLAFKIHMEAARAEVQAKPAFLNKEAVQREVKAVLSQKATLS-C----EVVDNAT 908 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + + + +++ + + V + K Q I N++ + + EV +E + Sbjct: 909 EVKWYKDGKQLSPSRAVQVDSKGKIRQLVICNVEKKDAGEYTC----EV----GTEKLAF 960 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530 + E K E K++ ++ L C + +V WY+DGK L + K + Sbjct: 961 KVQVAEIKSAFSNKESVQKDVKATVSQKATLACEVSDA-KTEVKWYKDGKLLTSTKTLHI 1019 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590 + G + + + + + V + E +K++ K Sbjct: 1020 ESKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHVAEAAVGFSNKESVKKEVKAALSQ 1079 Query: 1591 LVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 T E P EV WYK+G L + K ++ +K K + I+++ + + +YT EA Sbjct: 1080 KATLSCEVSDPKVEVKWYKDGKLLTSTKAVHMESKGKIRELVIEKMDKKDAGEYTCEAGA 1139 Query: 1650 TAGTSSVEVT---LKVYDKP-------SKPEGPVIMREISRESVTIEWKPPLDDGG--LE 1697 +++T +K K E V+ E++ E+ +++W DG E Sbjct: 1140 EKLLFKLQMTDEAVKFQKKAVNETCAVRASENIVLTTELTAENGSVKW---FRDGVELKE 1196 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 KY + K +K + +D +Y Q + E+ +V Sbjct: 1197 SKKYEMRKDGFSRTLIVKSTET-KDSGSYSCQTAQDKLEFKVQV 1239 Score = 124 bits (299), Expect = 3e-26 Identities = 124/560 (22%), Positives = 219/560 (39%), Gaps = 36/560 (6%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 EG D + +C V + + W K + + H L IT+V G Sbjct: 1347 EGKDAIFKCA-VTPADASVRWFHKSVPVTSGLKYKTEHSGNSH----TLTITSVTHEDAG 1401 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 + A + +A+L + + EP + L+++ V + L ++ P + Sbjct: 1402 EISFEAEGKSCKANLQV-------QHEPVMFKKKLENVTVEEQSEAKLEVEL-SKPSDEV 1453 Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W KN+ +P L DG ++ +LK D G+Y+ + + + T + VE Sbjct: 1454 RWMKNSVVIQPTGNLKICVDGAKQAL-VLKSVTQADRGIYSCETLDDK----TQGKLNVE 1508 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 + I E T E T+ L +++ V +W ++ + Sbjct: 1509 MKKIQ------VIKGLTETTAHETETVTLEVELSQADVDG-SWTKDGIKVKSGGNSRITV 1561 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 G+ L ++N+ E D+G+ V + G G + + E + E Sbjct: 1562 LGKKHALTLSNLKME-DAGN---VVFQAEGVRVSGRLIVL--EPPAMISKPIMDISVPEK 1615 Query: 944 KTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 + V EC+ S T KW+ + E+ I GR D G C Sbjct: 1616 EKVTFECEVSRTNTEVKWFKDNVELKPGKMFSIHSLGRKRTLVISKCSPEDAGTYICRTP 1675 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062 D TS L V ++KLQD EV EK+ A EI+ + D W + +K N Sbjct: 1676 DDNTSAKLSVHARDIRIVKKLQDVEVMEKESATFVCEISHDDVDCQWFKGSAKLKVSDN- 1734 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122 + G L R+ + D GE +A++ V ELP + + +L+++ + Sbjct: 1735 IKMRQEGRTYVLLFRSVTPEDMGEIKFTAEKACSSAKLKVKELPVKFVKKLRDKIAMYKH 1794 Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + E ++++ A V+W+K +EI+ ++ + +KL I + D D Y+C+ + Sbjct: 1795 RGHLECQVSRASAKVKWYKSKTEIKPGLKYEIQSEDVYRKLTINNVDEADEDTYTCDATD 1854 Query: 1183 SKCTAILTVEEPSINFTLRL 1202 K + L VEE SI+ L Sbjct: 1855 DKTSCKLLVEEQSISIVREL 1874 Score = 118 bits (284), Expect = 2e-24 Identities = 200/979 (20%), Positives = 358/979 (36%), Gaps = 68/979 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L + +V+K G Y + E A V + G V + +K+ + + L Sbjct: 1028 LVVDSVEKKDSGEY-ICEAGTEKLAFRLHVAEAAVGFSNKESVKKEVKAAL---SQKATL 1083 Query: 755 SAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 S +V +P+ + W K+ K KA+ +S G + I K K KD G YT +A Sbjct: 1084 SCEV-SDPKVEVKWYKDGKLLTSTKAVHMESKGKIRELVIEKMDK-KDAGEYTCEAG--- 1138 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 AE + ++ E +N + V+ I L +T S+ W+R+ Sbjct: 1139 --AE-KLLFKLQMTDEAVKFQKKAVN--ETCAVRASENIVLTTELTAEN-GSVKWFRDGV 1192 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + S+ DG + L++ + +++ DSG Y C + + + + E V Sbjct: 1193 ELKESKKYEMRKDGFSRTLIVKSTETK-DSGSYSCQTAQDKLEFKVQVKGMLHTEPVHNT 1251 Query: 932 KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 K + + G I + V K E+ G + G Sbjct: 1252 KIVGRCLPKTSGSDFISDAALKFVVPLK--AATVELEG--RYSVTTSGPQRILTVTNMKK 1307 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV 1048 D G C ++ TS V P IR KL + E AI + + A V Sbjct: 1308 EDEGEYSCECRNDRTSAS--VSSKAPRQIRLMAKLNNVAAMEGKDAIFKCAVTPADASVR 1365 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W + KY E G+ L I + + D GE S +SC A + V P Sbjct: 1366 WFHKSVPVTSGL-KYKTEHSGNSHTLTITSVTHEDAGEISFEAEGKSCKANLQVQHEPVM 1424 Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 +L+N V + ++A E+EL+K VRW K+ IQ + ++++ +DG KQ L + Sbjct: 1425 FKKKLENVTVEEQSEAKLEVELSKPSDEVRWMKNSVVIQPTGNLKICVDGAKQALVLKSV 1484 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228 D G YSCE + K L VE I L E T L VE+ +D + Sbjct: 1485 TQADRGIYSCETLDDKTQGKLNVEMKKIQVIKGLTETTAHETET-VTLEVELSQADVDGS 1543 Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-TKLKVEVVEFP 1287 W K ++ + KK L + +D V+ A+ ++ V+E P Sbjct: 1544 WTKDGIKVKSGGNSRITVLGKKHALTLSNLKMEDAGN---VVFQAEGVRVSGRLIVLEPP 1600 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 I + + VT + +W ++ +K K + +L I Sbjct: 1601 AMISKPIMDISVPEKEKVTFECEVSR-TNTEVKWFKDNVELKPGKMFSIHSLGRKRTLVI 1659 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 K DAG Y R ++ A + ++ + ++E +S++ +C Sbjct: 1660 SKCSPEDAGTYICRTPDDNTSAKLSVHARDIRIVKKLQDVEVMEKESATF-VC------- 1711 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 + + ++D +W K +I+ + +Y +V D+ + T Sbjct: 1712 --------EISHDDVD-CQWFKGSAKLKVSDNIKMRQEGRTYVLLFRSVTPEDMGEIKFT 1762 Query: 1468 TEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 E + K++ V+ K L++ L C KV WY+ ++K Sbjct: 1763 AEKACSSAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRA-SAKVKWYKSKTEIKPG 1821 Query: 1526 KATYENRX-----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN-ED 1579 YE + Y C A +D +TSC + ++++ + + Sbjct: 1822 -LKYEIQSEDVYRKLTINNVDEADEDTYTCDATDD----KTSCKLLVEEQSISIVRELSP 1876 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 ++ + V +E + PP +W NG ++ ++ + + + K+ K S Sbjct: 1877 VEVTEPFAAVFEVEISMELVKPP--VWTLNGVAVQESRDIEMEKEGTLHRLTFKKTKASM 1934 Query: 1640 SSKYTIEASNTAGTSSVEV 1658 + A + ++ + V Sbjct: 1935 TGSVQFTAGKSKSSAQLAV 1953 Score = 104 bits (250), Expect = 2e-20 Identities = 123/501 (24%), Positives = 195/501 (38%), Gaps = 58/501 (11%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L G P F +PKA V G D L C +V P P I W ++ + D+ Sbjct: 2 LFGGVPRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKDKLKLTSGGRFKAVEDGDV 61 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744 + L I + G Y A N GEA + LK+ + + P V++P S Sbjct: 62 YR----LTIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKP-AST 116 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEG 801 V G V +V +P W K+ + + + SD D ++ I + + D G Sbjct: 117 RVGLGGDVAFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSVRNL-DGG 175 Query: 802 VYTLKAENSEGIAETSAVITVE-------------------EPTEENAEPPLFINRFQE- 841 YT +A+N+ G A +A +TV+ + +E + + I R +E Sbjct: 176 TYTCRAQNTVGRAHAAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEES 235 Query: 842 -------ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDGENIELVIT 893 +V + KL VT +P P ITW ++ IS + EN L I Sbjct: 236 SITSSTVTSVTDGKHAKLSCFVTGHPKPHITWRKDGTNISEGRRHVIYEDQAENFILKIL 295 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953 + D+G Y C A N AG++ VT+ +V F + LQ E +E K+ +L C+ Sbjct: 296 YC-KQTDNGLYTCNAGNMAGQTYSAVLVTVKEPQVPFRRKLQ-DVEVQEKKSAMLLCEVP 353 Query: 954 HTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV 1012 + T W+ + + + QEG D GV C +K+ + V Sbjct: 354 LVATQTNWFMEETRLEQSSKYYMEQEGTLRRLTIHNVTTNDDGVYICEMKE---GSRTVA 410 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 + T+ + D I VE+ D W R+GE +K + ++ Sbjct: 411 ELTVRGMV----------NDTVIFCVELEHPCVDAYWTRNGEKLK-EDSRISIACSLRQY 459 Query: 1073 KLYIRNTSVHDEGEYSCILRD 1093 L IR+ D GE + + D Sbjct: 460 TLTIRDCQADDSGEVAFVAGD 480 Score = 71.3 bits (167), Expect = 3e-10 Identities = 80/350 (22%), Positives = 135/350 (38%), Gaps = 17/350 (4%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L D Y + + E + + +E AP+FV K G V F C+V Sbjct: 71 LEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDVAFVCRV 130 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 +P W + + S ++ D D +TL I+ V D GT+TC A+N G A Sbjct: 131 AAHPEANFEWEKDGRYLGESNRVKIVSDSDG-STLKIQSVRNLDGGTYTCRAQNTVGRAH 189 Query: 594 STTELIVEA-----PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 + L V+A ++D + + I + + V +G Sbjct: 190 AAAALTVDARDSRNMIADKNTSLLAHLQKRKEEMKKDISIYRSEESSITSSTVTS-VTDG 248 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 L C + P+P I W G I + V E + +LKI K+ G Y Sbjct: 249 KHAKLSCFVTGHPKPHITWRKDGTNI-SEGRRHVIYEDQAENF--ILKILYCKQTDNGLY 305 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 T A N G+ +++ +K E + P L+ + V++ +S +L +V T + Sbjct: 306 TCNAGNMAGQTYSAVLVTVK--EPQVP-FRRKLQDVEVQEKKSAMLLCEVPLVATQTNWF 362 Query: 769 CKNNKPVKALP--TKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAE 815 + + ++ + +G +TI D+GVY + E S +AE Sbjct: 363 MEETRLEQSSKYYMEQEGTLRRLTI-HNVTTNDDGVYICEMKEGSRTVAE 411 Score = 64.1 bits (149), Expect = 4e-08 Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 2/156 (1%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P + W +NG KL+ D +I + + I++ + S + A + ++ VT Sbjct: 431 PCVDAYWTRNGEKLKEDSRISIACSLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFAVT 490 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 P P V + + S+TI+W PP D + + Y +E+ + N W + Sbjct: 491 AARKHPPDPPVDAVTHNK-TESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPG 549 Query: 1720 DRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 + T I E Y FR+ A N G S LE Sbjct: 550 ETITSTEITICSFTEEASYQFRISAMNDFGQSPYLE 585 Score = 58.0 bits (134), Expect = 3e-06 Identities = 48/193 (24%), Positives = 83/193 (43%), Gaps = 17/193 (8%) Query: 1016 IPEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 +P F+ + + F V KD + + S T + WE+D ++ ++ + G + +L Sbjct: 6 VPRFLSRPKAFSVCVGKDATLSCTVVGSPTPLITWEKD-KLKLTSGGRFKAVEDGDVYRL 64 Query: 1075 YIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEI-------ITRLQNQKVNKGNKA 1124 I ++ D G+Y C ++ E+ A V LP E+ + + + +V G Sbjct: 65 TIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPTEMPHRAPVFVVKPASTRVGLGGDV 124 Query: 1125 TFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179 F + +A W KDG + SN +++ D LKI D G Y+C Sbjct: 125 AFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDGSTLKIQSVRNLDGGTYTCRAQNT 184 Query: 1180 VGNSKCTAILTVE 1192 VG + A LTV+ Sbjct: 185 VGRAHAAAALTVD 197 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-- 1922 PP P + V T S+T++W+ P+S+ PI YI+E + V K+W + G ++ Sbjct: 496 PPDPPVDAVTHNKTESSITIQWSPPDSDRPVPIKGYIVERRKVGNKTWQR-CNPGETITS 554 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVS 1949 E I + E+ FRISA N G S Sbjct: 555 TEITICSFTEEASYQFRISAMNDFGQS 581 Score = 45.6 bits (103), Expect = 0.015 Identities = 66/299 (22%), Positives = 119/299 (39%), Gaps = 33/299 (11%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXX--- 1544 K I ++ + L+C + +V WY+DGK L ++KA + E++ Sbjct: 789 KEIKATVSQKVTLSCEVSD-SKTEVKWYKDGKLLTSSKAIHAESKGRSRLLVIESVDKKD 847 Query: 1545 XXXYKC------IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C +AF H E + +Q KP ++ E ++++ K T E Sbjct: 848 AGEYMCDAGTEKLAFKIHMEAARA---EVQAKPAF-LNKEAVQREVKAVLSQKATLSCEV 903 Query: 1599 IP-PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 + EV WYK+G +L + + +K K + I +++ + +YT E V+ Sbjct: 904 VDNATEVKWYKDGKQLSPSRAVQVDSKGKIRQLVICNVEKKDAGEYTCEVGTEKLAFKVQ 963 Query: 1658 V-----------TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 V +++ K + + + E+S ++W DG L + + Sbjct: 964 VAEIKSAFSNKESVQKDVKATVSQKATLACEVSDAKTEVKW---YKDGKLLTSTKTLHIE 1020 Query: 1707 EPDNNRWIKVADVD-RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 +R + V V+ +D Y + E + V A+ VGFS ES +K AL Sbjct: 1021 SKGKSRQLVVDSVEKKDSGEYICEAGTEKLAFRLHV-AEAAVGFSNK-ESVKKEVKAAL 1077 Score = 44.4 bits (100), Expect = 0.035 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P+ V FEC+V ++ WF+ +KP + F ++ TLVI + PEDAGT+ Sbjct: 1613 PEKEKVTFECEVSR-TNTEVKWFKDNVELKPGKMFSIH-SLGRKRTLVISKCSPEDAGTY 1670 Query: 582 TC 583 C Sbjct: 1671 IC 1672 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 2/99 (2%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD-VNTL 2024 P PP + S+I + W P+ D P+ GY + R V W + + + Sbjct: 497 PDPPVDAVTHNKTESSITI-QWSPPDSDRPVPIKGYIVERRKVGNKTWQRCNPGETITST 555 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + I +E +Y RI A N+ G S LE F + P Sbjct: 556 EITICSFTEEASYQFRISAMNDFGQSPYLEVPGSFYLEP 594 >UniRef50_A5PF15 Cluster: Novel protein similar to human obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; n=1; Danio rerio|Rep: Novel protein similar to human obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1602 Score = 182 bits (444), Expect = 7e-44 Identities = 158/591 (26%), Positives = 245/591 (41%), Gaps = 30/591 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L I ++K G Y A G S + +K P + + L + V++GESV L Sbjct: 1039 LAIRDIKDSDAGIYECNA----GSVSTKATVTVKA---IPAEFTKELLNQEVKEGESVTL 1091 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEG 812 + P W K + +K+ S L VK D G YT + + Sbjct: 1092 MCEY-SIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQK- 1149 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 T A +TV NA P FI + +E T+ L +++ VP + W + + Sbjct: 1150 ---TMATVTV------NAVPISFIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQT 1199 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + P E +ELVI N E DSG Y CV + + K A + I + +TF + Sbjct: 1200 LCPGEKYQMRHIVTILELVIRNPVPE-DSGTYICVCEDQSTK----ADIKIRTQPITFKQ 1254 Query: 933 HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 L+ TEEG +VIL C+ S + +W + + +I Q G Sbjct: 1255 KLRNQM-TEEGSSVILHCEISKADIPVEWRKGNILLKSGEKYKIRQRGCILELKIFNLTQ 1313 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D G+ C + ETS + V F KL++ E L E++ V W + Sbjct: 1314 EDSGLYSCASETAETSANVTVSAQHVIFKEKLKNVVADEGKTITLHCEVSKTGVPVQWWK 1373 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 E+++ + KY +R +L I D G Y C+ D+ A + +V P Sbjct: 1374 GDELLQFGE-KYKMRERDTSVELIISEAVAEDSGVYRCVCGDQKTKATIKIVGAPATFKQ 1432 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 L+NQ+ +G T EL+K DA V W K I Q+ ++GK +L I + + Sbjct: 1433 DLKNQEALEGGSITLHCELSKSDAPVEWRKGDKLILPGPRFQMRLNGKTAELVISNVFPE 1492 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 DAG YSC G+ K TA + V+ I F L + + + A T E+ V W K Sbjct: 1493 DAGTYSCVTGDQKTTAEVKVKSLPITFKRELQNQVSIEGGS-AVFTCELSKPGAPVEWRK 1551 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + +++ K+ + + L I E D YTC D++ST +L V+ Sbjct: 1552 GRVILKAGAKYHTTLEGRLTKLAINNLVEGDAGNYTCKTKDSQSTAELTVQ 1602 Score = 179 bits (435), Expect = 9e-43 Identities = 170/728 (23%), Positives = 296/728 (40%), Gaps = 41/728 (5%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+K+ K + +E ++LEC P + WL KG ++ + + + D+ + L Sbjct: 806 FAKELKDVFAEEKGIVVLECE-TRQPATTVTWL-KGLMVLRSGHKYIMKKKDVLL---TL 860 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I N++K Y + A L + G+K +++ L+ +GE++I Sbjct: 861 TIFNLEKSDSAVYICDVGTMQSRALLTV-----QGQKVV--IVDELEDKECLEGETIIFR 913 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSE 811 ++ + + W + + G H++T K KD G +A + Sbjct: 914 CRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTF-KQLARKDTGTIIFEAGDKR 972 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 A S ++ PT A + E G++ L+ + T P I WY++ Sbjct: 973 SYA--SLLVRERRPTITKA--------LENTEAIEGGSLMLLCK-TSKPC-HIVWYKDGC 1020 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 +I S + G L I ++ + D+G Y+C +AG S A VT+ F Sbjct: 1021 LIWNSSKYLVSRSGNEARLAIRDI-KDSDAGIYEC----NAGSVSTKATVTVKAIPAEFT 1075 Query: 932 KHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 K L E +EG++V L C+ S + W + + + + Q Sbjct: 1076 KELLNQ-EVKEGESVTLMCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVK 1134 Query: 991 XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE 1050 D G CI +DQ+T + V FI++L++ E +E L E++ V W Sbjct: 1135 PDDSGNYTCICRDQKTMATVTVNAVPISFIKELKNQETEEGKTMTLRCELSKAGVPVEWL 1194 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII 1110 + + + P + KY I +L IRN D G Y C+ D+S A++ + P Sbjct: 1195 KGKQTLCPGE-KYQMRHIVTILELVIRNPVPEDSGTYICVCEDQSTKADIKIRTQPITFK 1253 Query: 1111 TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 +L+NQ +G+ E++K D V W K ++ ++ G +LKI++ Sbjct: 1254 QKLRNQMTEEGSSVILHCEISKADIPVEWRKGNILLKSGEKYKIRQRGCILELKIFNLTQ 1313 Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230 +D+G YSC ++ +A +TV + F +L + T L E+ + V W+ Sbjct: 1314 EDSGLYSCASETAETSANVTVSAQHVIFKEKLKNVVADEGKTIT-LHCEVSKTGVPVQWW 1372 Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKI 1290 K +++ EK+ + LII + +D Y CV D K TK +++V P Sbjct: 1373 KGDELLQFGEKYKMRERDTSVELIISEAVAEDSGVYRCVCGDQK--TKATIKIVGAPATF 1430 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 + G +TL + P EW K+I + ++ K+A L I V Sbjct: 1431 KQDLKNQEALEGGSITLHCELSKSDAPV-EWRKGDKLILPGPRFQMRLNGKTAELVISNV 1489 Query: 1351 ENTDAGIY 1358 DAG Y Sbjct: 1490 FPEDAGTY 1497 Score = 178 bits (434), Expect = 1e-42 Identities = 153/569 (26%), Positives = 247/569 (43%), Gaps = 38/569 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ IP F+K+ Q V EG + L C +IP W KG E + S Sbjct: 1067 VKAIPAEFTKELLNQEVKEGESVTLMCEY-SIPGIQFVWR-KGPETLKS---SEKYHMRQ 1121 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 C L I NVK G YT + +++ A++ + P I+ LK+ + Sbjct: 1122 RKSCISLAIHNVKPDDSGNYTCICRDQKTMATVTV-------NAVPISFIKELKNQETEE 1174 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL----KPKKVKDEGVYT 804 G+++ L ++ P + W K + + P + H +TIL + +D G Y Sbjct: 1175 GKTMTLRCELSKAGVP-VEWLKGKQTL--CPGEKYQMRHIVTILELVIRNPVPEDSGTYI 1231 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 E+ T A I + +P F + + +E ++ L +++ +P + Sbjct: 1232 CVCEDQS----TKADIKIR------TQPITFKQKLRNQMTEEGSSVILHCEISKADIP-V 1280 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + N ++ E G +EL I N+ E DSG Y C AS +A S A VT+ Sbjct: 1281 EWRKGNILLKSGEKYKIRQRGCILELKIFNLTQE-DSGLYSC-ASETAETS---ANVTVS 1335 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983 + V F + L K+ +EGKT+ L C+ S T V +W+ + + + ++ + Sbjct: 1336 AQHVIFKEKL-KNVVADEGKTITLHCEVSKTGVPVQWWKGDELLQFGEKYKMRERDTSVE 1394 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D GV +C+ DQ+T + + F + L++ E E L E++ Sbjct: 1395 LIISEAVAEDSGVYRCVCGDQKTKATIKIVGAPATFKQDLKNQEALEGGSITLHCELSKS 1454 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 A V W + ++I P ++ G +L I N D G YSC+ D+ TAEV V Sbjct: 1455 DAPVEWRKGDKLILPGP-RFQMRLNGKTAELVISNVFPEDAGTYSCVTGDQKTTAEVKVK 1513 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 LP LQNQ +G A F EL+K A V W K ++ T++G+ KL Sbjct: 1514 SLPITFKRELQNQVSIEGGSAVFTCELSKPGAPVEWRKGRVILKAGAKYHTTLEGRLTKL 1573 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 I + DAG Y+C+ +S+ TA LTV+ Sbjct: 1574 AINNLVEGDAGNYTCKTKDSQSTAELTVQ 1602 Score = 172 bits (419), Expect = 8e-41 Identities = 245/1047 (23%), Positives = 402/1047 (38%), Gaps = 94/1047 (8%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T K+ + V EG EC L + W G+ IV + I VA E + Sbjct: 626 TIVKRIRTATVLEGESCSFECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKY----T 681 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 + I V G V ++ E S +L +K ++P +V + ++ GE L Sbjct: 682 MSIEEVMTSDAGE-VVFSIK---ELSCRTMLFVK---EKPVRVFRDMLNVKATPGEDPEL 734 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 S ++ P T+ W KN + ++ P + D I+ + D G Y +A+ G Sbjct: 735 SCEIT-KPDATVKWLKNGRQIRVSPKYEITQKDYLVKLIIHNAAIMDSGEYCCEAD---G 790 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 IA T A + V + F +++ +EKG + L TR P ++TW + + Sbjct: 791 IA-TRARLDVRDLQHA------FAKELKDVFAEEKGIVVLECE-TRQPATTVTWLKGLMV 842 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + + L I N++ DS Y C G A +T+ +KV V Sbjct: 843 LRSGHKYIMKKKDVLLTLTIFNLEKS-DSAVYIC----DVGTMQSRALLTVQGQKVVIVD 897 Query: 933 HLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXX 989 L+ E EG+T+I C+ S KWY ++ + D EI+ G Sbjct: 898 ELEDK-ECLEGETIIFRCRICPSDYTDVKWYLDETLLYTNDLNEIMMIPGGYHTLTFKQL 956 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 D G I D+ + L+V+E P + L++ E E +L + S+ +VW Sbjct: 957 ARKDTGTIIFEAGDKRSYASLLVRERRPTITKALENTEAIEGGSLMLLCK-TSKPCHIVW 1015 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 +DG +I +KY + G+ +L IR+ D G Y C S A VTV +P E Sbjct: 1016 YKDGCLIW-NSSKYLVSRSGNEARLAIRDIKDSDAGIYECNAGSVSTKATVTVKAIPAEF 1074 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 L NQ+V +G T E + W K ++ S + L I++ Sbjct: 1075 TKELLNQEVKEGESVTLMCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVK 1134 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 DD+G Y+C + K A +TV I+F L T L E+ + V W Sbjct: 1135 PDDSGNYTCICRDQKTMATVTVNAVPISFIKELKNQETEEGKT-MTLRCELSKAGVPVEW 1193 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFP 1287 K K + EK+ + V L+IR +D Y CV D K+ K++ + + F Sbjct: 1194 LKGKQTLCPGEKYQMRHIVTILELVIRNPVPEDSGTYICVCEDQSTKADIKIRTQPITFK 1253 Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 K+ R + GS V L + P EW + ++K + K L I Sbjct: 1254 QKL----RNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKIRQRGCILELKI 1308 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 + D+G+Y E A+ NVT+ +++ N+ DE Sbjct: 1309 FNLTQEDSGLYSCASET----AETSANVTV-------SAQHVI-FKEKLKNVVADE---- 1352 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDA-S 1465 G + ++ V + W + L+ Y+ R + E+ IS+A + Sbjct: 1353 GKTITLHCEVSKTGVPVQWW----------KGDELLQFGEKYKMRERDTSVELIISEAVA 1402 Query: 1466 ETTEYYKVI---KETK-----IQSP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 E + Y+ + ++TK + +P T ++ LKN I L C P V W Sbjct: 1403 EDSGVYRCVCGDQKTKATIKIVGAPATFKQDLKNQEALEGGSITLHCELSKSDAP-VEW- 1460 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXX-----XXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 R G KL ++ R Y C+ G+ +T+ V ++ P Sbjct: 1461 RKGDKLILPGPRFQMRLNGKTAELVISNVFPEDAGTYSCVT----GDQKTTAEVKVKSLP 1516 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 IT E Q G + T + P V W K L+ +Y+ T + + + + Sbjct: 1517 -ITFKRELQNQVSIEGGSAVFTCELSK-PGAPVEWRKGRVILKAGAKYHTTLEGRLTKLA 1574 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEV 1658 I L + YT + ++ T+ + V Sbjct: 1575 INNLVEGDAGNYTCKTKDSQSTAELTV 1601 Score = 169 bits (412), Expect = 5e-40 Identities = 229/1062 (21%), Positives = 412/1062 (38%), Gaps = 92/1062 (8%) Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 LLEC+ V+ + W + +EIVP+ V E +Y ++ I +V E T+ Sbjct: 198 LLECQ-VSRANAVVEWFKRNQEIVPNRKYQVVSEG---VYRQLI-IEDVGSSDEDTFICD 252 Query: 712 AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 AV+ L + E++ ++ L S+ V + + + W N Sbjct: 253 AVDERTSCQLFV-------EEQAISILRGLSSVEVMEPKEACFKVETSIKLERAPKWTLN 305 Query: 772 NK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + P + + G +H + + + + + G +++ A +TV Sbjct: 306 GQILFPCPDIRIERQGTSHRLIF-----TQTDSSMCGTVQFTSGKSKSEAQLTV------ 354 Query: 829 NAEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 E PL + + ++ KE G++ L +P + W++ + S T + Sbjct: 355 -TERPLIVKQPISDVEEKENGSVTLSCEFCPSP-RVVRWFKGRTPLFASNKYTIKREKNR 412 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 +E+ I V + DSG+Y+CVA G + G +V + V+K+ ++HL++ E EE T + Sbjct: 413 VEMTILGVKAA-DSGEYRCVAG---GSETRG-KVNVKVKKLKIIRHLEQ-VEAEEDGTAV 466 Query: 948 LECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 C+ +H + S +W N K + +H IQ I D Sbjct: 467 FCCELNHESPSVQWLLNDKVLH-TNHINKIQNSGKVYSLILKRLTPQESRITFKSLDISE 525 Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFE 1066 S L V+E F R L+D +E+ +L+ E++ + VW +DGEI+ + KY+ Sbjct: 526 SAFLRVREKPAVFFRSLEDVAGEERGEILLQCEVSKPSVTPVWRKDGEILNSTE-KYEIL 584 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF 1126 G L I D GEYSC + A+VTV +L I+ R++ V +G +F Sbjct: 585 HVGKSLTLKIHKLIKEDGGEYSCDIGCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSF 644 Query: 1127 EIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 E L+ W +G I + I + +G+K + I + DAGE + C Sbjct: 645 ECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKYTMSIEEVMTSDAGEVVFSIKELSC 704 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245 +L V+E + + P D L+ EI V W K I + K+ + Sbjct: 705 RTMLFVKEKPVRVFRDMLNVKATPGE-DPELSCEITKPDATVKWLKNGRQIRVSPKYEIT 763 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYEREYRIKRGS 1303 LII D EY C + +L V ++ F ++ D E ++G Sbjct: 764 QKDYLVKLIIHNAAIMDSGEYCCEADGIATRARLDVRDLQHAFAKELKDVFAE---EKG- 819 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 + +L P W+ +++ +LTI +E +D+ +Y Sbjct: 820 -IVVLECETRQPATTVTWLKGLMVLRSGHKYIMKKKDVLLTLTIFNLEKSDSAVYIC--- 875 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 + G +T+ + ++ +D C + G + I + + Sbjct: 876 -DVGTMQSRALLTVQGQ-------KVVIVDELEDKECLE-----GETIIFRCRICPSDYT 922 Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYR---FRAYAVNEVD--ISDASETTEYYKVIKETK 1478 +W + + T + + Y F+ A + I +A + Y ++ + Sbjct: 923 DVKWYLDETLLYTNDLNEIMMIPGGYHTLTFKQLARKDTGTIIFEAGDKRSYASLL--VR 980 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXX 1534 + PT+ K L+N TE E L + + WY+DG K + N Sbjct: 981 ERRPTITKALEN--TEAIEGGSLMLLCKTSKPCHIVWYKDGCLIWNSSKYLVSRSGNEAR 1038 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y+C A G V T V ++ P + E + Q+ K G+ VT Sbjct: 1039 LAIRDIKDSDAGIYECNA----GSVSTKATVTVKAIPA-EFTKELLNQEVKEGES--VTL 1091 Query: 1595 VIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 + E IP + +W K L++ ++Y++ ++ + I +K S YT + Sbjct: 1092 MCEYSIPGIQFVWRKGPETLKSSEKYHMRQRKSCISLAIHNVKPDDSGNYTCICRDQKTM 1151 Query: 1654 SSVEVT------LKVYDKPSKPEGPVI-MR-EISRESVTIEW 1687 ++V V +K EG + +R E+S+ V +EW Sbjct: 1152 ATVTVNAVPISFIKELKNQETEEGKTMTLRCELSKAGVPVEW 1193 Score = 136 bits (328), Expect = 8e-30 Identities = 167/776 (21%), Positives = 294/776 (37%), Gaps = 73/776 (9%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 FV LR K ECQV + WF++ I P++ +Q+ + L+I Sbjct: 182 FVRPLRVKIAMYKHRALLECQVSR-ANAVVEWFKRNQEIVPNRKYQVV-SEGVYRQLIIE 239 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 +V D TF C A + ++ +L VE E + IL G Sbjct: 240 DVGSSDEDTFICDAVDER----TSCQLFVE--------EQAIS-------------ILRG 274 Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + +PK + I LE P+ W G+ + P +I + + H Sbjct: 275 LSSVEVMEPKEACFKVETSIKLE----RAPK----WTLNGQILFPCPDIRIERQGTSHR- 325 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L T GT + + EA L + + P V +P+ + ++ S Sbjct: 326 ---LIFTQTDSSMCGTVQFTSGKSKSEAQLTVT-------ERPLIVKQPISDVEEKENGS 375 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V LS + +PR + W K P+ A K + + +TIL K D G Y A Sbjct: 376 VTLSCEFCPSPR-VVRWFKGRTPLFASNKYTIKREKNRVEMTILGVKAA-DSGEYRCVA- 432 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G +ET + V+ + I +++ +E GT + PS+ W Sbjct: 433 ---GGSETRGKVNVK------VKKLKIIRHLEQVEAEEDGTAVFCCELNHES-PSVQWLL 482 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N++++ + G+ L++ + + +K + S A + + + Sbjct: 483 NDKVLHTNHINKIQNSGKVYSLILKRLTPQESRITFKSL------DISESAFLRVREKPA 536 Query: 929 TFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F + L+ E G+ ++L+C+ S +V+ W + + ++ + EI+ G+ Sbjct: 537 VFFRSLEDVAGEERGE-ILLQCEVSKPSVTPVWRKDGEILNSTEKYEILHVGKSLTLKIH 595 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD- 1046 D G C + +T + V++ +++++ V E + E ++ E D Sbjct: 596 KLIKEDGGEYSCDIGCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSFECVLSHEIIDE 655 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP 1106 W +G++I + + G + I D GE +++ SC + V E P Sbjct: 656 AFWNMNGQLIVSNR-RIIVANEGRKYTMSIEEVMTSDAGEVVFSIKELSCRTMLFVKEKP 714 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 + + N K G E+TK DA V+W K+G +I+ S ++T KL I+ Sbjct: 715 VRVFRDMLNVKATPGEDPELSCEITKPDATVKWLKNGRQIRVSPKYEITQKDYLVKLIIH 774 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 + + D+GEY CE A L V + F L + + L E Sbjct: 775 NAAIMDSGEYCCEADGIATRARLDVRDLQHAFAKELKD-VFAEEKGIVVLECETRQPATT 833 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 VTW K V+ K+ + TL I + D Y C + +S L V+ Sbjct: 834 VTWLKGLMVLRSGHKYIMKKKDVLLTLTIFNLEKSDSAVYICDVGTMQSRALLTVQ 889 Score = 120 bits (290), Expect = 3e-25 Identities = 116/494 (23%), Positives = 200/494 (40%), Gaps = 13/494 (2%) Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W R+ I G+N L +T V + D G + S A A +T+ Sbjct: 34 WTRDGVPIKSRPVCRIAMQGKNHTLTLTRV-TLADMG----IISFKAEGIETSAMLTVTA 88 Query: 926 EKVTFVKHLQKSYETE-EGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXX 984 + VK LQ TE E T I E V KWY + + D+ +I EG+ Sbjct: 89 RDIKIVKALQNVSVTERESLTFICEVNWED-VDGKWYKDNSRLKAGDNIKIRCEGKIHSL 147 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D G I+ + ++ ML VKE F+R L+ K A+LE +++ Sbjct: 148 TYKSVRSEDAGEIRFTAERVSSTAMLRVKELPVHFVRPLRVKIAMYKHRALLECQVSRAN 207 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 A V W + + I P + KY G R+L I + DE + C DE + ++ V E Sbjct: 208 AVVEWFKRNQEIVPNR-KYQVVSEGVYRQLIIEDVGSSDEDTFICDAVDERTSCQLFVEE 266 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 I+ L + +V + +A F++E + K + +W +G + I++ G +L Sbjct: 267 QAISILRGLSSVEVMEPKEACFKVETSIKLERAPKWTLNGQILFPCPDIRIERQGTSHRL 326 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 D G G SK A LTV E + + + + N L+ E Sbjct: 327 IFTQTDSSMCGTVQFTSGKSKSEAQLTVTERPLIVKQPISD-VEEKENGSVTLSCEFCPS 385 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 V W+K ++ + + K+T+ + + + I D EY CV +++ K+ V+V Sbjct: 386 PRVVRWFKGRTPLFASNKYTIKREKNRVEMTILGVKAADSGEYRCVAGGSETRGKVNVKV 445 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 + KI+ + + + + P+ +W++N K++ K K Sbjct: 446 KKL--KIIRHLEQVEAEEDGTAVFCCELN-HESPSVQWLLNDKVLHTNHINKIQNSGKVY 502 Query: 1344 SLTIKKVENTDAGI 1357 SL +K++ ++ I Sbjct: 503 SLILKRLTPQESRI 516 Score = 104 bits (250), Expect = 2e-20 Identities = 135/631 (21%), Positives = 263/631 (41%), Gaps = 39/631 (6%) Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITIL 792 ++++ L+++ V + ES+ +V W K+N +KA + + +G HS+T Sbjct: 92 KIVKALQNVSVTERESLTFICEVNWEDVDG-KWYKDNSRLKAGDNIKIRCEGKIHSLTY- 149 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K + +D G AE ++A++ V+E P F+ + K L Sbjct: 150 KSVRSEDAGEIRFTAER----VSSTAMLRVKEL------PVHFVRPLRVKIAMYKHRALL 199 Query: 853 VARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 +V+R N V + W++ N+ I P+ +G +L+I +V S D + C A + Sbjct: 200 ECQVSRANAV--VEWFKRNQEIVPNRKYQVVSEGVYRQLIIEDVGSS-DEDTFICDAVDE 256 Query: 912 AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISG 969 ++S ++ ++ + ++ ++ L S E E K + +TS + + KW N + + Sbjct: 257 --RTS--CQLFVEEQAISILRGL-SSVEVMEPKEACFKVETSIKLERAPKWTLNGQILFP 311 Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK-LQDFEV 1028 I ++G G ++ ++ L V E P +++ + D E Sbjct: 312 CPDIRIERQGTSHRLIFTQTDSSMCGTVQFTSGKSKSEAQLTVTER-PLIVKQPISDVEE 370 Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 KE L E V W + G NKY ++ + ++ I D GEY Sbjct: 371 KENGSVTLSCEFCPSPRVVRWFK-GRTPLFASNKYTIKREKNRVEMTILGVKAADSGEYR 429 Query: 1089 CILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 C+ +V V +II L+ + + A F EL V+W + ++ Sbjct: 430 CVAGGSETRGKVNVKVKKLKIIRHLEQVEAEEDGTAVFCCELNHESPSVQWLLN-DKVLH 488 Query: 1149 SNHI-QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 +NHI ++ GK L + ++ + S+ + E+P++ F R E + Sbjct: 489 TNHINKIQNSGKVYSLILKRLTPQESRITFKSLDISESAFLRVREKPAVFF--RSLEDVA 546 Query: 1208 VPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 + L E+ ++ W K ++ TEK+ ++ K TL I K ++D EY+ Sbjct: 547 GEERGEILLQCEVSKPSVTPVWRKDGEILNSTEKYEILHVGKSLTLKIHKLIKEDGGEYS 606 Query: 1268 CVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNS 1325 C + S TK KV V + IV R + G + ++ ++ + W +N Sbjct: 607 CDI--GCSQTKAKVTVRDLHITIVKRIRTATVLEGESCSFECVLSHEIIDEA--FWNMNG 662 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 ++I + + + + +++I++V +DAG Sbjct: 663 QLIVSNRRIIVANEGRKYTMSIEEVMTSDAG 693 Score = 104 bits (249), Expect = 3e-20 Identities = 160/781 (20%), Positives = 301/781 (38%), Gaps = 54/781 (6%) Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 ++ VK L+ + E+ + E SH V +W + I I +G+ Sbjct: 1 RIQLVKGLEDATLCEK-EACTFEVVLSHAYVRGQWTRDGVPIKSRPVCRIAMQGKNHTLT 59 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D+G+I + ETS ML V + ++ LQ+ V E++ E+N E Sbjct: 60 LTRVTLADMGIISFKAEGIETSAMLTVTARDIKIVKALQNVSVTERESLTFICEVNWEDV 119 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL 1105 D W +D +K N G I L ++ D GE S TA + V EL Sbjct: 120 DGKWYKDNSRLKAGDN-IKIRCEGKIHSLTYKSVRSEDAGEIRFTAERVSSTAMLRVKEL 178 Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + L+ + ++A E ++++ +A+V WFK EI + Q+ +G ++L I Sbjct: 179 PVHFVRPLRVKIAMYKHRALLECQVSRANAVVEWFKRNQEIVPNRKYQVVSEGVYRQLII 238 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF-ILVPANTDAYLTVEIPDET 1224 D D + C+ + + + L VEE +I+ L ++ P + I E Sbjct: 239 EDVGSSDEDTFICDAVDERTSCQLFVEEQAISILRGLSSVEVMEPKEACFKVETSIKLER 298 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 W ++ + LI + T+ C T KS ++ ++ V Sbjct: 299 AP-KWTLNGQILFPCPDIRIERQGTSHRLIFTQ-TDSSMCG-TVQFTSGKSKSEAQLTVT 355 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 E P + + K VTL ++ P+ + + + K+T + Sbjct: 356 ERPLIVKQPISDVEEKENGSVTLSCEFCPSPRVVRWFKGRTPLFASNKYTIKR-EKNRVE 414 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 +TI V+ D+G Y+ + V + V L K + E D +++ C Sbjct: 415 MTILGVKAADSGEYRCVAGGSETRGKVNVKVKKL-KIIRHLEQVEAEEDGTAVFCC---- 469 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 E S + +++ + + T ++N K + I T R +DIS++ Sbjct: 470 ELNHESPSVQWLLNDKVLHTNHINKIQNSGKVYSLILKRLTPQESRI---TFKSLDISES 526 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT--WYRDGKKL 1522 + + +V ++ + + L+++ E +I L C V +P VT W +DG+ L Sbjct: 527 A----FLRVREKPAV----FFRSLEDVAGEERGEILLQC---EVSKPSVTPVWRKDGEIL 575 Query: 1523 KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIK 1581 + + YE +K I D GE SC +G Q K +T+ + I Sbjct: 576 NSTE-KYE-----ILHVGKSLTLKIHKLIK-EDGGEY--SCDIGCSQTKAKVTVRDLHIT 626 Query: 1582 QKHKV-------GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 ++ G+ V+ E W NG + +++ + + + + I+E Sbjct: 627 IVKRIRTATVLEGESCSFECVLSHEIIDEAFWNMNGQLIVSNRRIIVANEGRKYTMSIEE 686 Query: 1635 LKRSHSSKYTIEASNTAGTSSV---EVTLKVYD-----KPSKPEGPVIMREISRESVTIE 1686 + S + + + + + E ++V+ K + E P + EI++ T++ Sbjct: 687 VMTSDAGEVVFSIKELSCRTMLFVKEKPVRVFRDMLNVKATPGEDPELSCEITKPDATVK 746 Query: 1687 W 1687 W Sbjct: 747 W 747 Score = 49.2 bits (112), Expect = 0.001 Identities = 25/73 (34%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F + L+ + +G ++ C++ P + W + +I P FQM + A LVI Sbjct: 1430 FKQDLKNQEALEGGSITLHCELSKSDAP-VEWRKGDKLILPGPRFQMRLNG-KTAELVIS 1487 Query: 572 EVFPEDAGTFTCV 584 VFPEDAGT++CV Sbjct: 1488 NVFPEDAGTYSCV 1500 Score = 47.2 bits (107), Expect = 0.005 Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F+++L+ + T +G T+ C++ P + W + + P + +QM + + LVIR Sbjct: 1163 FIKELKNQETEEGKTMTLRCELSKAGVP-VEWLKGKQTLCPGEKYQMRHIV-TILELVIR 1220 Query: 572 EVFPEDAGTFTCVAKN 587 PED+GT+ CV ++ Sbjct: 1221 NPVPEDSGTYICVCED 1236 Score = 41.9 bits (94), Expect = 0.19 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 V K T +++ F ++L + +G +V C+ P Q W + +K S+ + Sbjct: 1059 VSTKATVTVKAIPAEFTKELLNQEVKEGESVTLMCEYS-IPGIQFVWRKGPETLKSSEKY 1117 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 M ++ L I V P+D+G +TC+ ++ A+ T + Sbjct: 1118 HMRQRKSCIS-LAIHNVKPDDSGNYTCICRDQKTMATVTVNAV 1159 Score = 41.9 bits (94), Expect = 0.19 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 IF EKL+ +G T+ C+V P + W++ +++ + ++M D +V L+I Sbjct: 1340 IFKEKLKNVVADEGKTITLHCEVSKTGVP-VQWWKGDELLQFGEKYKMRERDTSVE-LII 1397 Query: 571 REVFPEDAGTFTCV 584 E ED+G + CV Sbjct: 1398 SEAVAEDSGVYRCV 1411 Score = 37.1 bits (82), Expect = 5.3 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F +KLR + T +GS+V C++ P + W + ++K + +++ + L I Sbjct: 1252 FKQKLRNQMTEEGSSVILHCEISKADIP-VEWRKGNILLKSGEKYKI-RQRGCILELKIF 1309 Query: 572 EVFPEDAGTFTCVAKNAAGFASST 595 + ED+G ++C ++ A A+ T Sbjct: 1310 NLTQEDSGLYSCASETAETSANVT 1333 >UniRef50_Q4SI34 Cluster: Chromosome 5 SCAF14581, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5 SCAF14581, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1276 Score = 182 bits (443), Expect = 1e-43 Identities = 133/480 (27%), Positives = 223/480 (46%), Gaps = 23/480 (4%) Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 F+RKL ++V + L VE+ + ADV W ++G+ P +Y FE G++R L I Sbjct: 341 FLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPT-GRYIFESVGNMRYLTIN 399 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 N S+ D+ Y C++ +E T+E+ V E P I+ L++Q V KG++ E E+++ A V Sbjct: 400 NCSLADDAAYCCVVGEEKSTSELFVKEPPVLIVKNLEDQMVMKGDRVELECEVSEEGANV 459 Query: 1138 RWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195 +W KDG E+ + DG K L I D +D G Y + + A L V+E Sbjct: 460 KWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVKTNGGESMAELLVQEKE 519 Query: 1196 INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII 1255 + + + + V A A E+ DE + TWYK + ++ + + + L I Sbjct: 520 LEIYQSIAD-LTVKAKDQALFKCEVSDENVRGTWYKNGAEVKPDARINITHIGRIHKLTI 578 Query: 1256 RKCTEDDQCEYTCV------LLDAK-STTKLKVEVV--EFPPKI-VD-----YEREYRIK 1300 D+ +YT V L AK + ++K++ V + PPKI +D E + Sbjct: 579 DDVKPGDEGDYTFVPDGYAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIVVV 638 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYK 1359 G+ + L V P P W K++ + +K + TI+ E D GIY Sbjct: 639 AGNKLRLDVPITGDPAPTVIWTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYS 698 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 + + N G ++NV ++D P PP + IL + S + WD P G II YV+E Sbjct: 699 VVVRNAAGEDTADINVKVVDVPDPPQEVKILSVGEESCVVQWDPPAFDGGQPIIGYVLER 758 Query: 1420 QEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 ++ + W ++ +T + + +Y R YAVN + +S S+ ++ + + T Sbjct: 759 KKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFVPVAPT 818 Score = 153 bits (371), Expect = 5e-35 Identities = 160/642 (24%), Positives = 276/642 (42%), Gaps = 43/642 (6%) Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 + F++ L +Y+ +G + L + ++ KW N +E G Sbjct: 337 KSAAFLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPTGRYIFESVGNMRYL 396 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D C+V ++++++ L VKE ++ L+D V + D LE E++ E Sbjct: 397 TINNCSLADDAAYCCVVGEEKSTSELFVKEPPVLIVKNLEDQMVMKGDRVELECEVSEEG 456 Query: 1045 ADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 A+V WE+DG E+ + + KY F+K G L I + + D G Y AE+ V Sbjct: 457 ANVKWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVKTNGGESMAELLVQ 516 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 E EI + + V ++A F+ E++ + W+K+G+E++ I +T G+ KL Sbjct: 517 EKELEIYQSIADLTVKAKDQALFKCEVSDENVRGTWYKNGAEVKPDARINITHIGRIHKL 576 Query: 1164 KIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRL--PEF------------IL 1207 I D D G+Y+ +A L E I++ R P+ I+ Sbjct: 577 TIDDVKPGDEGDYTFVPDGYAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIV 636 Query: 1208 VPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI-IRKCTEDDQCE 1265 V A L V I D V W K + V+ + + + K + I D+ Sbjct: 637 VVAGNKLRLDVPITGDPAPTVIWTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGI 696 Query: 1266 YTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV--DYQAFP--QPND 1319 Y+ V+ +A + T + V+VV+ P D +E +I + + +V D AF QP Sbjct: 697 YSVVVRNAAGEDTADINVKVVDVP----DPPQEVKILSVGEESCVVQWDPPAFDGGQPII 752 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCG---HADVEMN 1374 +++ K K + + + D + T + + Y++R+ N+ G H+ Sbjct: 753 GYVLERKKKKSYRWMRLNFDPYPET-TYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQP 811 Query: 1375 VTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNI 1433 + S P + +I +SI + W PE G+ + Y VEY + T EWI + + + Sbjct: 812 FVPVAPTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPAAQGL 871 Query: 1434 T-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LK 1489 T +T I+NL T +FR A N S A+ T I+E +Q P + P + Sbjct: 872 TERTSLIIRNLTTGDRLQFRVRAYNMAGPSPAA-TLAQPITIREI-MQRPKILLPRNLRQ 929 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 + + + L F G P+PKVTW ++G+ L + A+ N Sbjct: 930 TLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRN 971 Score = 126 bits (304), Expect = 7e-27 Identities = 117/493 (23%), Positives = 207/493 (41%), Gaps = 34/493 (6%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G++ + I G P P VIW K G K+ E D ++ + + + I+ +R Y+ Sbjct: 640 GNKLRLDVPITGDPAPTVIWTK-GEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYS 698 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + N AG + ++ +KV D P P+ I+ + ES ++W PP DGG + Y +E Sbjct: 699 VVVRNAAGEDTADINVKVVDVPDPPQEVKIL-SVGEESCVVQWDPPAFDGGQPIIGYVLE 757 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 + + + RW+++ TY +++ E Y RV A N +G S ++ + A Sbjct: 758 RKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFVPVA- 816 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKW--KXXXXXXX 1821 P+ I + S+ + W P E+ G + Y VE +EG +W Sbjct: 817 --PTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPAAQGLTER 874 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--QPRNF------V 1873 I+ L+ QFR+ A N G S T ITI + + P PRN Sbjct: 875 TSLIIRNLTTGDRLQFRVRAYNMAGPSPAATLAQPITIREIMQRPKILLPRNLRQTLIRR 934 Query: 1874 VSESTSRSVTLKW-TEPE---SNGGSPITNYIIEFKTVKGKS-----WTKIVTVGGSVHE 1924 V ++ + + + P+ S G P+++ + + +G + T+ G + Sbjct: 935 VGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRNSEGDTILFIRKTEKTHSGKYDLQ 994 Query: 1925 HCIENIKEKDEIIFRI--SAENTVGVS--LPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 IEN+++ + ++ +++ V S T + L + +P PP + + G Sbjct: 995 VQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFLLIRVLDLPGPPEVLKIVDVWGF 1054 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 N+ + W P+ DG + GY + D W V + DL + Y+ R Sbjct: 1055 NVAL-EWKPPKDDGNCEITGYTVQKADKKTMEWFTVYD-QYRRTHCIVSDLIMGNEYVFR 1112 Query: 2041 IYARNEIGLS-EP 2052 ++A N +G S EP Sbjct: 1113 VFANNLVGPSPEP 1125 Score = 80.2 bits (189), Expect = 6e-13 Identities = 64/211 (30%), Positives = 100/211 (47%), Gaps = 34/211 (16%) Query: 1567 IQQKPVITISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 I Q+P I + +++Q +VGD + +G P P+V W KNG L + +I Sbjct: 915 IMQRPKILLPR-NLRQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLA-SIRNS 972 Query: 1625 EKTSVIRIKELKRSHSSKY--TIEASNTAGTSSVE------------------------V 1658 E +++ I++ +++HS KY ++ N T+SV + Sbjct: 973 EGDTILFIRKTEKTHSGKYDLQVQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFL 1032 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 ++V D P PE I+ ++ +V +EWKPP DDG E+T Y ++K + W V D Sbjct: 1033 LIRVLDLPGPPEVLKIV-DVWGFNVALEWKPPKDDGNCEITGYTVQKADKKTMEWFTVYD 1091 Query: 1719 VDRDVETYCI-QKLNENCEYMFRVIAQNPVG 1748 R T+CI L EY+FRV A N VG Sbjct: 1092 QYR--RTHCIVSDLIMGNEYVFRVFANNLVG 1120 Score = 68.1 bits (159), Expect = 2e-09 Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 18/160 (11%) Query: 1912 WTK---IVTVG-GSVHE-----HCI---ENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 WTK +VT G G VH HCI E + +DE I+ + N G T +V++ Sbjct: 659 WTKGEKVVTEGDGRVHVESTKGHCIFTIEGAERQDEGIYSVVVRNAAGED--TADINVKV 716 Query: 1960 EKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 VP PP ++I VG + W P +DGG P++GY + + WM + Sbjct: 717 ---VDVPDPPQE-VKILSVGEESCVVQWDPPAFDGGQPIIGYVLERKKKKSYRWMRLNFD 772 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 + + + E Y +R+YA N IG+S ++ +PF Sbjct: 773 PYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPF 812 Score = 66.9 bits (156), Expect = 6e-09 Identities = 85/348 (24%), Positives = 135/348 (38%), Gaps = 63/348 (18%) Query: 1295 REYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS--LTIKKVE 1351 R+ I+R G V L++ +Q P+P W N + + T SI + L I+K E Sbjct: 928 RQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSS---TLASIRNSEGDTILFIRKTE 984 Query: 1352 NTDAGIYKLR--LENNCGHADVEMNVT------------------------ILDKPSPPG 1385 T +G Y L+ +EN A V + V +LD P PP Sbjct: 985 KTHSGKYDLQVQIENVEDTASVTLQVVGRSDSRVWTSGGGSTGTLIFLLIRVLDLPGPPE 1044 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLK 1444 I+++ ++ + W P++ GN I Y V+ + T EW +V +T + +L Sbjct: 1045 VLKIVDVWGFNVALEWKPPKDDGNCEITGYTVQKADKKTMEWFTVYDQYRRTHCIVSDLI 1104 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV-------------------- 1484 + Y FR +A N V S T+ I++T Q P V Sbjct: 1105 MGNEYVFRVFANNLVGPSPEPCGTKDSAYIQKTGGQQPHVVTSSGVVYKPPTHKEHDLSE 1164 Query: 1485 ----EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540 +PL + + L+C GVP+PKVTWY++ L +A Y Sbjct: 1165 APKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSN-EAKYRMLSNHGVLTL 1223 Query: 1541 XX-----XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583 Y C A ND GE C + ++ + + E+ K++ Sbjct: 1224 EIRKPCPFDGGVYTCKAVNDSGEDTVECKLEVRSQIIKEDKKEESKKE 1271 Score = 60.1 bits (139), Expect = 7e-07 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%) Query: 497 VFEKPTSEEQSM--APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 V++ PT +E + AP F L + G T C V G P+P++TW++ + Sbjct: 1151 VYKPPTHKEHDLSEAPKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSNEA 1210 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 ++M + V TL IR+ P D G +TC A N +G Sbjct: 1211 KYRM-LSNHGVLTLEIRKPCPFDGGVYTCKAVNDSG 1245 Score = 55.2 bits (127), Expect = 2e-05 Identities = 46/225 (20%), Positives = 84/225 (37%), Gaps = 9/225 (4%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + + RN G T+D + + PP + + V E S ++W P +GG P Sbjct: 697 YSVVVRNAAGED---TADINVKVVDVPDPPQEVKILSVGEE---SCVVQWDPPAFDGGQP 750 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 I Y++E K K W ++ + + + E R+ A N++G+S +++ Sbjct: 751 IIGYVLERKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQ 810 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + P+ L + + ++ W PE G L GY + W+ Sbjct: 811 PFV---PVAPTSEPVGLCVDDISDTSIVLKWRPPERMGSVDLEGYGVEYCKEGTDEWIPA 867 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + IR+L+ R+ A N G S +P + Sbjct: 868 AQGLTERTSLIIRNLTTGDRLQFRVRAYNMAGPSPAATLAQPITI 912 Score = 52.4 bits (120), Expect = 1e-04 Identities = 48/182 (26%), Positives = 84/182 (46%), Gaps = 28/182 (15%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-VL 725 W G E+ PD I++ +H L I +VK EG YT V S + L Sbjct: 552 WYKNGAEVKPDARINITHIGRIHK----LTIDDVKPGDEGDYTFVPDGYAYNLSAKLNFL 607 Query: 726 KIKTG---EKEPPQV-IEPL-----KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 ++K ++PP++ ++ + +++V G + L + G+P PT+ W K K V Sbjct: 608 EVKIDYVPRQDPPKIHLDCMGRTAESTIVVVAGNKLRLDVPITGDPAPTVIWTKGEKVV- 666 Query: 777 ALPTKSDGDT-------HSITILKPKKVKDEGVYTLKAENSEG--IAETSA-VITVEEPT 826 T+ DG H I ++ + +DEG+Y++ N+ G A+ + V+ V +P Sbjct: 667 ---TEGDGRVHVESTKGHCIFTIEGAERQDEGIYSVVVRNAAGEDTADINVKVVDVPDPP 723 Query: 827 EE 828 +E Sbjct: 724 QE 725 Score = 50.8 bits (116), Expect = 4e-04 Identities = 73/281 (25%), Positives = 107/281 (38%), Gaps = 33/281 (11%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 K A V +G I L VA + D+ WL G+E P ES +M L I Sbjct: 344 KLDPAYQVTKGHKIRLAVE-VANADADVKWLKNGQEFHPTGR--YIFESVGNM--RYLTI 398 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSA 756 N + Y V + + L + KEPP +++ L+ +V +G+ V L Sbjct: 399 NNCSLADDAAYCCVVGEEKSTSELFV--------KEPPVLIVKNLEDQMVMKGDRVELEC 450 Query: 757 QVVGNPRPTITWCKNNKPVKALPT-----KSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + V + W K+ + + K DG H I I+ +D G Y +K E Sbjct: 451 E-VSEEGANVKWEKDGVELTRDESFKYRFKKDGCKH-ILIINDATKEDCGHYKVKTNGGE 508 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 +AE + V+E E ++TVK K V+ V TWY+N Sbjct: 509 SMAE----LLVQEKELE------IYQSIADLTVKAKDQALFKCEVSDENVRG-TWYKNGA 557 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 + P I G +L I +V D GDY V A Sbjct: 558 EVKPDARINITHIGRIHKLTIDDVKPG-DEGDYTFVPDGYA 597 Score = 50.8 bits (116), Expect = 4e-04 Identities = 68/303 (22%), Positives = 121/303 (39%), Gaps = 26/303 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P K + Q V +G + LEC V+ ++ W G E+ DE+ + D + Sbjct: 428 PVLIVKNLEDQMVMKGDRVELECE-VSEEGANVKWEKDGVELTRDESFKYRFKKDGCKH- 485 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +L I + K G Y V E A L + EKE ++ + + + V+ + Sbjct: 486 -ILIINDATKEDCGHYKVKTNGGESMAELLVQ------EKEL-EIYQSIADLTVKAKDQA 537 Query: 753 ILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + +V + TW KN KP + G H +TI K DEG YT + Sbjct: 538 LFKCEV-SDENVRGTWYKNGAEVKPDARINITHIGRIHKLTI-DDVKPGDEGDYTFVPDG 595 Query: 810 -SEGIAETSAVITVEEPTEENAEPPLF----INRFQE--ITVKEKGTIKLVARVTRNPVP 862 + ++ + V+ +PP + R E I V ++L +T +P P Sbjct: 596 YAYNLSAKLNFLEVKIDYVPRQDPPKIHLDCMGRTAESTIVVVAGNKLRLDVPITGDPAP 655 Query: 863 SITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 ++ W + ++++ + ++ G I I + + D G Y V N+AG+ + Sbjct: 656 TVIWTKGEKVVTEGDGRVHVESTKGHCI-FTIEGAERQ-DEGIYSVVVRNAAGEDTADIN 713 Query: 921 VTI 923 V + Sbjct: 714 VKV 716 Score = 47.2 bits (107), Expect = 0.005 Identities = 21/67 (31%), Positives = 35/67 (52%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G+P P+V WYKN L N+ +Y + + + I++ YT +A N +G + Sbjct: 1189 VRGVPKPKVTWYKNKMDLSNEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAVNDSGEDT 1248 Query: 1656 VEVTLKV 1662 VE L+V Sbjct: 1249 VECKLEV 1255 Score = 46.8 bits (106), Expect = 0.007 Identities = 48/186 (25%), Positives = 73/186 (39%), Gaps = 7/186 (3%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 E+ S F +L V L VE+ + DV W K T ++ S R Sbjct: 335 EKKSAAFLRKLDPAYQVTKGHKIRLAVEVANADADVKWLKNGQEFHPTGRYIFESVGNMR 394 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 L I C+ D Y CV+ + KST++L V+ E P IV + + +G V L + Sbjct: 395 YLTINNCSLADDAAYCCVVGEEKSTSELFVK--EPPVLIVKNLEDQMVMKGDRVELECEV 452 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 N +W + + + + K D L I D G YK++ N G + Sbjct: 453 SE-EGANVKWEKDGVELTRDESFKYRFKKDGCKHILIINDATKEDCGHYKVK--TNGGES 509 Query: 1370 DVEMNV 1375 E+ V Sbjct: 510 MAELLV 515 Score = 46.4 bits (105), Expect = 0.009 Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 E P+ PL S V G + LS V G P+P +TW KN + H + L Sbjct: 1164 EAPKFTRPLVSRSVIAGYTATLSCSVRGVPKPKVTWYKNKMDLSNEAKYRMLSNHGVLTL 1223 Query: 793 KPKK--VKDEGVYTLKAENSEG 812 + +K D GVYT KA N G Sbjct: 1224 EIRKPCPFDGGVYTCKAVNDSG 1245 Score = 46.0 bits (104), Expect = 0.011 Identities = 45/188 (23%), Positives = 83/188 (44%), Gaps = 9/188 (4%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G+ + L+ + P P + W KGE++V + + V +ES +C + I ++ EG Sbjct: 640 GNKLRLDVPITGDPAPTVIWT-KGEKVVTEGDGRVHVESTKG-HC-IFTIEGAERQDEGI 696 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y+VV N GE + I +K+ +PPQ ++ L + + V +P I Sbjct: 697 YSVVVRNAAGEDTADINVKV-VDVPDPPQEVKILS--VGEESCVVQWDPPAFDGGQPIIG 753 Query: 768 WCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEGVYTLK--AENSEGIAETSAVITVEE 824 + K K+ + + D + T + K++ + Y ++ A NS G++ S Sbjct: 754 YVLERKKKKSYRWMRLNFDPYPETTYEAKRMIEGVAYEMRVYAVNSIGMSRHSQASQPFV 813 Query: 825 PTEENAEP 832 P +EP Sbjct: 814 PVAPTSEP 821 Score = 43.2 bits (97), Expect = 0.081 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 9/91 (9%) Query: 735 PQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHS 788 P+++ P L+ ++R+ G++V L G PRP +TW KN +P+ A S+GDT Sbjct: 919 PKILLPRNLRQTLIRRVGDTVNLVIPFQGKPRPKVTWSKNGEPLSSTLASIRNSEGDT-- 976 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 I ++ + G Y L+ + E + +T++V Sbjct: 977 ILFIRKTEKTHSGKYDLQVQ-IENVEDTASV 1006 Score = 39.9 bits (89), Expect = 0.75 Identities = 22/64 (34%), Positives = 28/64 (43%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 G+ FE E K DA V+W + +I N + DG K L I DA Y+ Sbjct: 24 GSSVVFEAETEKPDAKVKWQCNAKDIANGNKYTIAADGSKHSLSIKAVTHQDANIYAVIS 83 Query: 1181 GNSK 1184 G SK Sbjct: 84 GGSK 87 Score = 38.7 bits (86), Expect = 1.7 Identities = 34/151 (22%), Positives = 58/151 (38%), Gaps = 5/151 (3%) Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGT 849 +P KD Y K + TS+ + + PT + +E P F +V T Sbjct: 1124 EPCGTKDSA-YIQKTGGQQPHVVTSSGVVYKPPTHKEHDLSEAPKFTRPLVSRSVIAGYT 1182 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 L V P P +TWY+N +S +E + + + D G Y C A Sbjct: 1183 ATLSCSVRGVPKPKVTWYKNKMDLS-NEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAV 1241 Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 N +G+ + ++ + + + K + ET Sbjct: 1242 NDSGEDTVECKLEVRSQIIKEDKKEESKKET 1272 Score = 36.3 bits (80), Expect = 9.2 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEV 1283 VTWYK K + + K+ ++S+ TL IRK D YTC ++ + T + K+EV Sbjct: 1197 VTWYKNKMDLSNEAKYRMLSNHGVLTLEIRKPCPFDGGVYTCKAVNDSGEDTVECKLEV 1255 >UniRef50_Q4TAD5 Cluster: Chromosome undetermined SCAF7373, whole genome shotgun sequence; n=28; Euteleostei|Rep: Chromosome undetermined SCAF7373, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1090 Score = 180 bits (438), Expect = 4e-43 Identities = 204/895 (22%), Positives = 350/895 (39%), Gaps = 73/895 (8%) Query: 831 EPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 +PP F+ + T VK L RV+ + +I WY+N+ I+ F + Sbjct: 196 KPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSAR 255 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 L + + E DSG Y C N AG +S + +T+ E +FVK E GK L Sbjct: 256 LQLLSAAFE-DSGIYTCEVHNDAGSASCSSVLTVQ-EPPSFVK-TPSPLEGIRGKDASLH 312 Query: 950 CQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---- 1003 C+ S W +K + +II+ G D GV +C V + Sbjct: 313 CEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT 372 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGE-IIKPKKN 1061 + T T + +KE P F++KL D V + L + SE D+ W +D + +++ N Sbjct: 373 ESTRTAISLKEP-PAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDN 431 Query: 1062 K-YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIITRLQNQ 1116 + FEK + L + G+Y+C L ++S A VT++E P I+ ++ Sbjct: 432 RTITFEKS--VVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLE-PAAIVDSPESL 488 Query: 1117 KVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 + G E+ + L RWFK E+ N Q++ K LKI D DAGE Sbjct: 489 NIQTGEAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGE 548 Query: 1176 YSCEVGN----SKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 Y EV N + CT L V + I +F +L + LV + I L +W Sbjct: 549 YKLEVSNHVGVASCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASW 608 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288 + I+ + + L ++ D YTC +A T++ V V PP Sbjct: 609 FHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPP 668 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 V+ G++V+ + +W S+ + + S+ A+L + Sbjct: 669 SFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVATLVLN 728 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTIL----------DKPSPPGKPNILEIDSSS-- 1396 KVE AG Y ++ N G + +++ D GKP LE+ + Sbjct: 729 KVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEVSFAGTP 788 Query: 1397 -INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS------IQNLKTNSSY 1449 +N+ W + ++ +Y V+ DT+ + V N + + + + N N Sbjct: 789 RVNVTWKKDGGLIWASYLYNVIT---TDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVC 845 Query: 1450 RFRAYAVNEVDISDASETTEYYK--------VIKET--------KIQSPTVEKPLKNITT 1493 + + E+ E + +I+ T K + + LK+ T Sbjct: 846 EAHVSILERPSFVERMESVEINEGDSLLLRCLIEGTPEISVSWFKAEPVHFTRKLKDTTF 905 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXY 1548 + ++L C + G P+ V W +DGK + + + T + Y Sbjct: 906 TLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVLEILNSDRPAAGGTY 965 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-HKVGDEWLVTAVIEGIPPPEVIWY 1607 C N G + V ++ K + + + G + A + G P V WY Sbjct: 966 ACAISNGAGSDKCHARVSLEHKTAPSFTRRPPESLVDSEGKTVKIEARVSGSQPLNVTWY 1025 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 K+ N++ + Y ++ +++ +K +S S YT ASN AG +S V++ + Sbjct: 1026 KDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTI 1080 Score = 155 bits (375), Expect = 2e-35 Identities = 179/789 (22%), Positives = 307/789 (38%), Gaps = 45/789 (5%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAI-PEP-DIAWLFKGEEIVPDENISVAIESD 687 E +PPT V L C + P P +++W GEE+ +I+V ++ Sbjct: 99 ELVPPTSPMVYTRSEVQLTEPNTLVCLVTGFYPAPVNVSWTRNGEEVTQGTSINVPYPNN 158 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIV 746 + + ++ V Q+G V P + + T +PPQ ++ L + V Sbjct: 159 EGTFTQISRLDFVP--QQGDIYSCRVQH------PALSEADTRMWKPPQFVQKLPPTTFV 210 Query: 747 RQGESVILSAQVVGNPRPTITWCKNN-KPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804 + E L +V + I W KN+ K TK GD + L +D G+YT Sbjct: 211 KLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSARLQLLSAAFEDSGIYT 270 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 + N G A S+V+TV+ EPP F+ + L V +P + Sbjct: 271 CEVHNDAGSASCSSVLTVQ-------EPPSFVKTPSPLEGIRGKDASLHCEVAGSPPFQV 323 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TW + +++ S G ++ L I ++ + D+G Y+C SN+ G S +++ Sbjct: 324 TWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVD-DAGVYECQVSNNVGTESTRTAISLK 382 Query: 925 VEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYH-NKKEISGMDHREIIQEGRXX 982 E FVK L +S E T+ + S + W N + D+R I E Sbjct: 383 -EPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVV 441 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE---FIRKLQDFEVKEKDVAILEVE 1039 G C + +Q + V T+ E + + ++ + LEV Sbjct: 442 SLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQTGEAVALEVT 501 Query: 1040 I-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---- 1094 I S W + G+ NKY + L I++ D GEY + + Sbjct: 502 ICGSAELKTRWFK-GDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYKLEVSNHVGVA 560 Query: 1095 SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNH 1151 SCT + V + +PP I +L++ + G + ++ L WF DG EI+ Sbjct: 561 SCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKEIKSGLS 620 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFIL 1207 ++ KL++ D G Y+C+ G S+ +A + V EP +F Sbjct: 621 YDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPP-SFVETPEAQES 679 Query: 1208 VPANTDAYLTVEIPDETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 +P N ++ L V W++ + ++ + D TL++ K EY Sbjct: 680 LPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKD-DVATLVLNKVEMHHAGEY 738 Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 TC +L+ V + V P V R+ ++G + L V + P+ N W + Sbjct: 739 TCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDG 798 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTD-AGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 +I S L + + + AG Y L+N G+ E +V+IL++PS Sbjct: 799 GLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSILERPSFV 858 Query: 1385 GKPNILEID 1393 + +EI+ Sbjct: 859 ERMESVEIN 867 Score = 144 bits (350), Expect = 2e-32 Identities = 153/706 (21%), Positives = 296/706 (41%), Gaps = 45/706 (6%) Query: 1046 DVVWERDGE-IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE-YSCILRDESCTAEVTVV 1103 +V W R+GE + + + R V +G+ YSC ++ + + T + Sbjct: 135 NVSWTRNGEEVTQGTSINVPYPNNEGTFTQISRLDFVPQQGDIYSCRVQHPALSEADTRM 194 Query: 1104 ELPPEIITRLQNQKVNKGNKA-TFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ 1161 PP+ + +L K N+ + E ++ +L + W+K+ +I + +L Sbjct: 195 WKPPQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSA 254 Query: 1162 KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 +L++ +D+G Y+CEV G++ C+++LTV+EP +F ++ P + DA L Sbjct: 255 RLQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQEPP-SF-VKTPSPLEGIRGKDASLH 312 Query: 1218 VEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 E+ VTW K++ +++D+ K+ +I TL I K DD Y C + + T Sbjct: 313 CEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGT 372 Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHT 1334 + + ++ PP V + + G +TL + + WI N +++ + Sbjct: 373 ESTRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNR 432 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + + SL + + ++ AG Y RL N G A +VT+L+ + P L I + Sbjct: 433 TITFEKSVVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQT 492 Query: 1395 SSINICWDEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFR 1452 E G++ + + +E+ + + K T IQ+ + ++ Sbjct: 493 GEAVAL--EVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYK 550 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQP 1511 N V ++ + T + K+ P+ + L++ + +L C + G P Sbjct: 551 LEVSNHVGVASCTVT-----LAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLT 605 Query: 1512 KVTWYRDGKKLKTAKA---TY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 +W+ DGK++K+ + +Y +N Y C A N G ETS V + Sbjct: 606 -ASWFHDGKEIKSGLSYDISYVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNV 664 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 + P + E Q+ G+ A + G P +V W++ ++ + + +I+ K+ Sbjct: 665 AEPPSFVETPE--AQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDV 722 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---------SKPEGPVIMREI 1678 + + + +++ H+ +YT + N G S V L V + S +G + E+ Sbjct: 723 ATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEKGKPLRLEV 782 Query: 1679 S---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 S V + WK DGGL Y D + ++V + DR Sbjct: 783 SFAGTPRVNVTWK---KDGGLIWASYLYNVITTDTSCILEVLNSDR 825 Score = 123 bits (297), Expect = 5e-26 Identities = 141/675 (20%), Positives = 269/675 (39%), Gaps = 40/675 (5%) Query: 1017 PEFIRKLQDFE-VKEKDVAILEVEINS-ETADVVW-ERDGEIIKPKKNKYDFEKRGHIRK 1073 P+F++KL VK + LE ++S ++ ++ W + D +I K F + Sbjct: 198 PQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLS--AR 255 Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129 L + + + D G Y+C + ++ SC++ +TV E PP + + +G A+ E Sbjct: 256 LQLLSAAFEDSGIYTCEVHNDAGSASCSSVLTVQE-PPSFVKTPSPLEGIRGKDASLHCE 314 Query: 1130 LTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT-- 1186 + V W K+ ++ S ++ G L I ++DDAG Y C+V N+ T Sbjct: 315 VAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSVTLHIIKLEVDDAGVYECQVSNNVGTES 374 Query: 1187 --AILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS-VIEDTEKFT 1243 ++++EP + + ++V TV+ E LD++W + V+ D + T Sbjct: 375 TRTAISLKEPPAFVKKLMDQSVMVGEQLTLTATVK-GSEPLDISWIQDNDHVLRDGDNRT 433 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK-IVDYEREYRIKRG 1302 + + +LI+ + +YTC L + V P IVD I+ G Sbjct: 434 ITFEKSVVSLIVPQADSATAGKYTCRLSNQSGVALSVCHVTLLEPAAIVDSPESLNIQTG 493 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 V L V + W + + + S K A+L I+ + DAG YKL + Sbjct: 494 EAVALEVTICGSAELKTRWFKGDRELSAGNKYQMSSTKKVATLKIQSADKADAGEYKLEV 553 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIY-YVVEYQ 1420 N+ G A + + + DK PP L + D + + G++ + + + + Sbjct: 554 SNHVGVASCTVTLAVSDKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGK 613 Query: 1421 EIDT--TEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 EI + + IS V NI K + +Q ++T R+ A N S+ S + + + Sbjct: 614 EIKSGLSYDISYVDNICKLR--LQTVQTTDGGRYTCKAANAAGTSETSASVNVAE--PPS 669 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRX 1533 +++P ++ L P ++ G KV W+R +++ + + ++ Sbjct: 670 FVETPEAQESL------PGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDVA 723 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y C N G+ + +++ DI + G + Sbjct: 724 TLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPVHFVKKLRDISCEK--GKPLRLE 781 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS-KYTIEASNTAG 1652 G P V W K+G + YN+ T + + ++ + R ++ Y+ N G Sbjct: 782 VSFAGTPRVNVTWKKDGGLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVG 841 Query: 1653 TSSVEVTLKVYDKPS 1667 E + + ++PS Sbjct: 842 NDVCEAHVSILERPS 856 Score = 78.2 bits (184), Expect = 2e-12 Identities = 58/195 (29%), Positives = 88/195 (45%), Gaps = 10/195 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS---I 789 EP LK G+ + L G+PR ++ W K+ KP+ A + T+S + Sbjct: 892 EPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCVL 951 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG- 848 IL + G Y N G + A +++E T P F R E V +G Sbjct: 952 EILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKT-----APSFTRRPPESLVDSEGK 1006 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 T+K+ ARV+ + ++TWY++N I +F N+ ++ S+ SG Y C A Sbjct: 1007 TVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSF-VNNLAILCLKNSSKSQSGVYTCSA 1065 Query: 909 SNSAGKSSHGARVTI 923 SN AGK+S VTI Sbjct: 1066 SNEAGKASCLVSVTI 1080 Score = 75.4 bits (177), Expect = 2e-11 Identities = 59/307 (19%), Positives = 126/307 (41%), Gaps = 19/307 (6%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 + + +L ++ + G T A + PP+F + P+AQ G++ Sbjct: 625 YVDNICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPPSFVETPEAQESLPGNN 684 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + ++ + W E++ ++++ D+ + L + V+ G YT Sbjct: 685 VSFCAKVRGSSPLKVKWFRGSREMLHGRGCHISLKDDV----ATLVLNKVEMHHAGEYTC 740 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 +N G+ S P+ L ++ EP ++ L+ + +G+ + L G PR +TW K Sbjct: 741 QVLNPVGKKSYPVYLSVR----EPVHFVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKK 796 Query: 771 NNKPVKA--LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 + + A L DT I +L +++ G Y+ +N G A +++ Sbjct: 797 DGGLIWASYLYNVITTDTSCILEVLNSDRMEAAGTYSCHLDNGVGNDVCEAHVSI----- 851 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GE 886 E P F+ R + + + E ++ L + P S++W++ + + F G+ Sbjct: 852 --LERPSFVERMESVEINEGDSLLLRCLIEGTPEISVSWFKAEPVHFTRKLKDTTFTLGQ 909 Query: 887 NIELVIT 893 ++L+ T Sbjct: 910 PLQLLCT 916 Score = 71.7 bits (168), Expect = 2e-10 Identities = 76/325 (23%), Positives = 125/325 (38%), Gaps = 21/325 (6%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 FV+KLR G ++ E G PR +TW + +I S + + D + V+ Sbjct: 763 FVKKLRDISCEKGKPLRLEVSFAGTPRVNVTWKKDGGLIWASYLYNVITTDTSCILEVLN 822 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP--------LSDHGSEMTVXXXXXXXXX 622 E AGT++C N G + I+E P + + + + Sbjct: 823 SDRMEAAGTYSCHLDNGVGNDVCEAHVSILERPSFVERMESVEINEGDSLLLRCLIEGTP 882 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 + P F++K K G + L C P +AW G+ I +V Sbjct: 883 EISVSWFKAEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNV 942 Query: 683 AIESDMHMYCSVLKITNV-KKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE 739 + C VL+I N + GTY N G + + L+ KT P Sbjct: 943 RTTNSS---C-VLEILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKTA---PSFTRR 995 Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI--LKPKKV 797 P +S++ +G++V + A+V G+ +TW K+N + + +++ I LK Sbjct: 996 PPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSK 1055 Query: 798 KDEGVYTLKAENSEGIAETSAVITV 822 GVYT A N G A +T+ Sbjct: 1056 SQSGVYTCSASNEAGKASCLVSVTI 1080 Score = 62.1 bits (144), Expect = 2e-07 Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 3/190 (1%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 AEP F + ++ T ++L+ + +P S+ W ++ + I S + Sbjct: 891 AEPVHFTRKLKDTTFTLGQPLQLLCTYSGSPRVSVAWTKDGKPIWASYQYNVRTTNSSCV 950 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVIL 948 L I N D G Y C SN AG ARV+++ + +F + +S EGKTV + Sbjct: 951 LEILNSDRPAAGGTYACAISNGAGSDKCHARVSLEHKTAPSFTRRPPESLVDSEGKTVKI 1010 Query: 949 ECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 E + S ++ WY + EI + E+ GV C ++ Sbjct: 1011 EARVSGSQPLNVTWYKDNNEICSCHNYEMSFVNNLAILCLKNSSKSQSGVYTCSASNEAG 1070 Query: 1007 STMLVVKETI 1016 +V TI Sbjct: 1071 KASCLVSVTI 1080 Score = 56.4 bits (130), Expect = 8e-06 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 ++ + P F+ KLR H G + +C+V G +WF IK + + Y DN Sbjct: 570 DKLIPPSFIRKLRDSHLVVGKSGDLDCKVIGSAPLTASWFHDGKEIKSGLSYDISY-VDN 628 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + L ++ V D G +TC A NAAG + ++ + V P S Sbjct: 629 ICKLRLQTVQTTDGGRYTCKAANAAGTSETSASVNVAEPPS 669 Score = 50.8 bits (116), Expect = 4e-04 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+ P G C+V G P Q+TW ++ ++K S+ +++ +V TL Sbjct: 292 PSFVKTPSPLEGIRGKDASLHCEVAGSPPFQVTWSKEQKLLKDSRKYKIIKAGSSV-TLH 350 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I ++ +DAG + C N G S+ T + ++ P Sbjct: 351 IIKLEVDDAGVYECQVSNNVGTESTRTAISLKEP 384 Score = 48.8 bits (111), Expect = 0.002 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 503 SEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 S E AP F + P+ D G TV+ E +V G +TW++ I +++M + Sbjct: 983 SLEHKTAPSFTRR-PPESLVDSEGKTVKIEARVSGSQPLNVTWYKDNNEICSCHNYEMSF 1041 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + N+A L ++ +G +TC A N AG AS + + + H Sbjct: 1042 VN-NLAILCLKNSSKSQSGVYTCSASNEAGKASCLVSVTISGMSASH 1087 Score = 46.8 bits (106), Expect = 0.007 Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 1/106 (0%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E S + P FVE + + G+ V F +V G ++ WFR + + + + Sbjct: 657 ETSASVNVAEPPSFVETPEAQESLPGNNVSFCAKVRGSSPLKVKWFRGSREMLHGRGCHI 716 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 DD VATLV+ +V AG +TC N G S L V P+ Sbjct: 717 SLKDD-VATLVLNKVEMHHAGEYTCQVLNPVGKKSYPVYLSVREPV 761 Score = 43.2 bits (97), Expect = 0.081 Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 2/97 (2%) Query: 510 PIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P FV+KL P EC+V I W++ I + ++ + D + Sbjct: 198 PQFVQKLPPTTFVKLNEGHSLECRVSSSQSLNICWYKNDHKITDGANTKLMFGDLSARLQ 257 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 ++ F ED+G +TC N AG AS ++ L V+ P S Sbjct: 258 LLSAAF-EDSGIYTCEVHNDAGSASCSSVLTVQEPPS 293 Score = 37.9 bits (84), Expect = 3.0 Identities = 22/94 (23%), Positives = 40/94 (42%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV+KL + G + V+G I+W + + D + + +V +L+ Sbjct: 385 PAFVKKLMDQSVMVGEQLTLTATVKGSEPLDISWIQDNDHVLRDGDNRTITFEKSVVSLI 444 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + AG +TC N +G A S + + P Sbjct: 445 VPQADSATAGKYTCRLSNQSGVALSVCHVTLLEP 478 >UniRef50_UPI0000D55C03 Cluster: PREDICTED: similar to CG33484-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG33484-PA - Tribolium castaneum Length = 3764 Score = 178 bits (434), Expect = 1e-42 Identities = 199/749 (26%), Positives = 308/749 (41%), Gaps = 96/749 (12%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T E + AP F+ L G ++ EC+V G P P +TW ++ Sbjct: 1545 TPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTHNGKALQ---------F 1595 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 + N ATL++ E FP+DAGT+ AKN AG ASS + V+ L S+ + Sbjct: 1596 EGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSDSEL-------- 1647 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 A +E + P+ V EG+ + L+C +V PEP++ W + + Sbjct: 1648 ----ASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQ 1703 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI------KTGEKE-- 733 + + D CS++ I G Y VVA+N GEAS L + K E E Sbjct: 1704 LLFQGDR---CSLI-IQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEP 1759 Query: 734 ---PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI- 789 PP+ + L ++V +GE V V G P P I W NN+P+ PT TH+ Sbjct: 1760 PGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPIT--PTDHVKITHNSD 1817 Query: 790 -TI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTE-----ENAEPPLFINR 838 TI + + +D+GVYT+KA NS G A+ A + V+ +P E E P F Sbjct: 1818 GTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKEL 1877 Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898 F + E + K V P P + W N E I+ + + G+ L I + + Sbjct: 1878 FNDRVAFEGTSTKFECIVVGKPTPKVRWLFNGEPITGRKILIST-SGDRQVLTIPEISKD 1936 Query: 899 IDSGDYKCVASNSAGKSSHGARVTI-DVEKVT-------FVKHLQKSYETEEGKTVILEC 950 ++ G CVA N GK+S A +++ V +T +H++ SY Sbjct: 1937 LE-GTITCVAENEVGKASCAAHLSVQSVSTITLPEFSRDISQHVESSYILNREVHTQSST 1995 Query: 951 QTSHTVST--------KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 TS + T H+ + ++I QE VG + Sbjct: 1996 STSRKMETFTGTQEPQVQVHSFSQKDQQSFKQINQEAPQISESHKIEEYHQVGKQPPTII 2055 Query: 1003 DQETS------TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER--DG- 1053 ++ +S T ++TI + K K + + +I + DVV E DG Sbjct: 2056 EKSSSLFTTGTTEETKQKTIEHVVHKPVIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQ 2115 Query: 1054 ---EIIKPKKNKYDFEKRG---HIRK----LYIRNTSVHDEGEYSCILRDES----CTAE 1099 EI K + E G H + + I+N ++ D G Y+C +E+ TA+ Sbjct: 2116 PTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGRYTCTAVNEAGKAISTAD 2175 Query: 1100 VTV--VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEI--QFSNHIQL 1154 + V PP RLQ Q V KG++ E+E+T D V W+KDG I + ++ Sbjct: 2176 LVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARI 2235 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 G L I +L+ +G + NS Sbjct: 2236 RSMGNSHTLVIEKAELNMSGRFMVRAVNS 2264 Score = 153 bits (371), Expect = 5e-35 Identities = 135/494 (27%), Positives = 212/494 (42%), Gaps = 61/494 (12%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F L +GS F C V G P P +TWF+ I+ + D+Q +D + TL Sbjct: 1353 APVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQ-GLCTL 1411 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I E F ED+ +TC A NAAG A ++ L V+ ++ +++ Sbjct: 1412 TIEETFAEDSAKYTCKAINAAGSAETSACLSVKE--TEPEEQLS---------------- 1453 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 PPTF K + EG+ C++ P P + W FK E + + V ++ Sbjct: 1454 ----PPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQW-FKNYECIDNSPDYVITYNNG 1508 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVR 747 ++LK V + YT A N G A L + E E P+ I PL +++ R Sbjct: 1509 E---AILKFDKVSLEDKAEYTCKATNELGVAQSTASLTVTPLEPTEAPKFILPLSNVMAR 1565 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 G+ + L +V G P P +TW N K + + +G+ ++ + + KD G Y + A Sbjct: 1566 AGQKIKLECEVSGLPPPILTWTHNGKAL-----QFEGNKATLLVFEAFP-KDAGTYVVNA 1619 Query: 808 ENSEGIAETSAVITVEE--PTE-------ENAEP--PLFINRFQEITVKEKGTIKLVARV 856 +N G A ++ ++V+ PTE + EP P ++V E ++L + Sbjct: 1620 KNIAGEASSACSVSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVI 1679 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P + WY ++ + S F G+ L+I E D+G YK VA NSAG++S Sbjct: 1680 VGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQEALPE-DAGQYKVVALNSAGEAS 1738 Query: 917 HGARVTIDVEKVT--------------FVKHLQKSYETEEGKTVILECQTSH-TVSTKWY 961 +T+ + T F K L +E K C T T KW Sbjct: 1739 SKCSLTVVPDSGTKPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWL 1798 Query: 962 HNKKEISGMDHREI 975 N + I+ DH +I Sbjct: 1799 LNNQPITPTDHVKI 1812 Score = 118 bits (283), Expect = 2e-24 Identities = 127/491 (25%), Positives = 195/491 (39%), Gaps = 52/491 (10%) Query: 500 KPTSEEQ--SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 KP E+ P F + L +G V+FE V G P P+I W I P+ + Sbjct: 1752 KPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVK 1811 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617 + ++ D L I V PED G +T A N++G A +LIV++ Sbjct: 1812 ITHNSDGTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPE---------- 1861 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 +I G P+F + + EG+ EC +V P P + WLF GE I Sbjct: 1862 ----IIKHEEIKSG--PSFKELFNDRVAFEGTSTKFECIVVGKPTPKVRWLFNGEPIT-G 1914 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-----TGEK 732 I ++ D VL I + K EGT T VA N G+AS L ++ T + Sbjct: 1915 RKILISTSGDR----QVLTIPEISKDLEGTITCVAENEVGKASCAAHLSVQSVSTITLPE 1970 Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK-PVKALPTKSDGDTHSITI 791 + + ++S + E S+ T T + + V + K I Sbjct: 1971 FSRDISQHVESSYILNREVHTQSSTSTSRKMETFTGTQEPQVQVHSFSQKDQQSFKQINQ 2030 Query: 792 LKPKKVKDEGV--YTLKAENSEGIAETSAVI----TVEEPTEENAE-----------PPL 834 P+ + + Y + I E S+ + T EE ++ E PP Sbjct: 2031 EAPQISESHKIEEYHQVGKQPPTIIEKSSSLFTTGTTEETKQKTIEHVVHKPVIKTRPPK 2090 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 FI V + + L V P P ITW +N E + S + +FD + +VI N Sbjct: 2091 FITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKN 2150 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTI--DVEKVTFVKHLQKSYETEEGKTVILECQT 952 + D+G Y C A N AGK+ A + + V F + LQ + ++G VI+E + Sbjct: 2151 ATID-DAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQ-AQVVKKGDRVIMEVEV 2208 Query: 953 SHT--VSTKWY 961 + T + WY Sbjct: 2209 TGTPDPTVTWY 2219 Score = 116 bits (278), Expect = 9e-24 Identities = 133/527 (25%), Positives = 219/527 (41%), Gaps = 60/527 (11%) Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 EA+ L+ + + E P PL I+++G V G P P +TW K+ ++ Sbjct: 1337 EAARIQALEAQKPKIEAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQN 1396 Query: 778 LP---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT-EENAEPP 833 P T D ++TI + +D YT KA N+ G AETSA ++V+E EE PP Sbjct: 1397 NPDYQTTFDQGLCTLTI-EETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPP 1455 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELV 891 F+ + + +E + +V NP+P++ W++N E I SP IT N +GE I L Sbjct: 1456 TFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYN-NGEAI-LK 1513 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI----DVEKVTFVKHLQKSYETEEGKTVI 947 V E D +Y C A+N G + A +T+ E F+ L + G+ + Sbjct: 1514 FDKVSLE-DKAEYTCKATNELGVAQSTASLTVTPLEPTEAPKFILPL-SNVMARAGQKIK 1571 Query: 948 LECQTSHTVS--TKWYHNKK--EISGMDHREIIQEG----------RXXXXXXXXXXXXD 993 LEC+ S W HN K + G ++ E Sbjct: 1572 LECEVSGLPPPILTWTHNGKALQFEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACS 1631 Query: 994 VGVIKCIVKDQETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILE-VEINSETADVVWER 1051 V V + + S + E + P L + V E + L+ V + +V+W Sbjct: 1632 VSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYH 1691 Query: 1052 DGEIIKPKKNKYDFEK--RGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVE- 1104 D +P K DF+ +G L I+ D G+Y + + S +TVV Sbjct: 1692 DD---RPVKESPDFQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPD 1748 Query: 1105 -------------LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN 1150 PP+ L + V++G K FE +T + ++W + I ++ Sbjct: 1749 SGTKPPEPEEPPGTPPKFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTD 1808 Query: 1151 HIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192 H+++T + +L+I + +D G Y+ + G++KC A L V+ Sbjct: 1809 HVKITHNSDGTIRLEIANVRPEDKGVYTVKATNSSGDAKCFAQLIVK 1855 Score = 95.5 bits (227), Expect = 1e-17 Identities = 65/206 (31%), Positives = 107/206 (51%), Gaps = 11/206 (5%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +++ PP F + VD+ D++LE + P P+I W GE++ E+ V I D Sbjct: 2083 VIKTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQL--RESSGVQIHFD 2140 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + V+K + G YT AVN G+A L ++ PP L++ +V+ Sbjct: 2141 RNKVSVVIKNATID--DAGRYTCTAVNEAGKAISTADLVVRK-TVFPPVFGRRLQAQVVK 2197 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTK----SDGDTHSITILKPKKVKDEGV 802 +G+ VI+ +V G P PT+TW K+ P+ +AL K S G++H++ I K ++ G Sbjct: 2198 KGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEK-AELNMSGR 2256 Query: 803 YTLKAENSEGIAETSAVITVEEPTEE 828 + ++A NS G A++ A I V EPT + Sbjct: 2257 FMVRAVNSGGEAQSIADIAVFEPTPD 2282 Score = 83.0 bits (196), Expect = 8e-14 Identities = 94/441 (21%), Positives = 173/441 (39%), Gaps = 41/441 (9%) Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 +++ + + A K K+E F + D I+ GS T + P P Sbjct: 1331 EEEAKLEAARIQALEAQKPKIEAPVFTSPLSDAI----IQEGSRFTFMCHVTGTPVPVVT 1386 Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD- 1379 W + I+ + + D +LTI++ D+ Y + N G A+ +++ + Sbjct: 1387 WFKDGISIQNNPDYQTTFDQGLCTLTIEETFAEDSAKYTCKAINAAGSAETSACLSVKET 1446 Query: 1380 KP----SPPGKPNILEIDSSSINICWD---EPENTGNSTIIYYVVEYQEIDTT-EWISVK 1431 +P SPP +LE S+ + + E T+ ++ Y+ ID + +++ Sbjct: 1447 EPEEQLSPPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFK-NYECIDNSPDYVITY 1505 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 N + + + A NE+ ++ ++T V ++P PL N+ Sbjct: 1506 NNGEAILKFDKVSLEDKAEYTCKATNELGVA---QSTASLTVTPLEPTEAPKFILPLSNV 1562 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 + I+L C G+P P +TW +GK L+ N+ Y Sbjct: 1563 MARAGQKIKLECEVSGLPPPILTWTHNGKALQFE----GNKATLLVFEAFPKDAGTYVVN 1618 Query: 1552 AFNDHGEVETSCVVGIQQK-PVITISNEDIKQKHKV---------------GDEWLVTAV 1595 A N GE ++C V ++ + P T +E V G+ + V Sbjct: 1619 AKNIAGEASSACSVSVKGRLPTETSDSELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCV 1678 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P PEVIWY + ++ ++ + + + I+E + +Y + A N+AG +S Sbjct: 1679 IVGQPEPEVIWYHDDRPVKESPDFQLLFQGDRCSLIIQEALPEDAGQYKVVALNSAGEAS 1738 Query: 1656 VEVTLKVY----DKPSKPEGP 1672 + +L V KP +PE P Sbjct: 1739 SKCSLTVVPDSGTKPPEPEEP 1759 Score = 83.0 bits (196), Expect = 8e-14 Identities = 139/635 (21%), Positives = 239/635 (37%), Gaps = 72/635 (11%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + L + + +G++ TF +T +V WFKDG IQ + Q T D L I Sbjct: 1354 PVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQGLCTLTI 1413 Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFI--LVP------ANTD 1213 + +D+ +Y+C+ G+++ +A L+V+E L P F+ L P A Sbjct: 1414 EETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPPTFVKLLEPGSAREGAGFQ 1473 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD- 1272 Y VE + V W+K I+++ + + + + L K + +D+ EYTC + Sbjct: 1474 FYCKVE-GNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYTCKATNE 1532 Query: 1273 ---AKSTTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 A+ST L V +E PK + + G + L + P P W N K Sbjct: 1533 LGVAQSTASLTVTPLEPTEAPKFILPLSNVMARAGQKIKLECEVSGLPPPILTWTHNGKA 1592 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK-PSPPGK 1386 ++ + A+L + + DAG Y + +N G A +V++ + P+ Sbjct: 1593 LQ--------FEGNKATLLVFEAFPKDAGTYVVNAKNIAGEASSACSVSVKGRLPTETSD 1644 Query: 1387 PNI---LEIDSSSINICWDEPENT-GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ- 1441 + +E SI + T GN + V+ Q W K Q Sbjct: 1645 SELASDMEPVKPSIQLPLTNVSVTEGNRVRLDCVIVGQPEPEVIWYHDDRPVKESPDFQL 1704 Query: 1442 -------NLKTNSSYRFRAYAVNEVDISDASETTE--YYKVIKETKIQSPTVEKP----- 1487 +L + A V ++ A E + V+ ++ + P E+P Sbjct: 1705 LFQGDRCSLIIQEALPEDAGQYKVVALNSAGEASSKCSLTVVPDSGTKPPEPEEPPGTPP 1764 Query: 1488 -----LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATY--ENRXXXXX 1537 L ++ E +E G P P++ W + + + K T+ + Sbjct: 1765 KFTKLLSDVLVSEGEKVEFEGCVTGEPTPEIKWLLNNQPITPTDHVKITHNSDGTIRLEI 1824 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQ--------KHKVGD 1588 Y A N G+ + + ++ KP I +E+IK +V Sbjct: 1825 ANVRPEDKGVYTVKATNSSGDAKCFAQLIVKSMKPPEIIKHEEIKSGPSFKELFNDRVAF 1884 Query: 1589 EWLVT---AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 E T ++ G P P+V W NG + ++ I+T V+ I E+ + T Sbjct: 1885 EGTSTKFECIVVGKPTPKVRWLFNGEPI-TGRKILISTSGDRQVLTIPEISKDLEGTITC 1943 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 A N G +S L V S P R+IS+ Sbjct: 1944 VAENEVGKASCAAHLSV-QSVSTITLPEFSRDISQ 1977 Score = 79.0 bits (186), Expect = 1e-12 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 9/194 (4%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITI- 791 PP+ I P+ IV Q V+L V G P P ITW KN + ++ + + D + +++ Sbjct: 2088 PPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVV 2147 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 +K + D G YT A N G A ++A + V + PP+F R Q VK+ + Sbjct: 2148 IKNATIDDAGRYTCTAVNEAGKAISTADLVVRK----TVFPPVFGRRLQAQVVKKGDRVI 2203 Query: 852 LVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + VT P P++TWY++ I + + G + LVI + + SG + A Sbjct: 2204 MEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNM-SGRFMVRAV 2262 Query: 910 NSAGKSSHGARVTI 923 NS G++ A + + Sbjct: 2263 NSGGEAQSIADIAV 2276 Score = 76.6 bits (180), Expect = 7e-12 Identities = 36/97 (37%), Positives = 54/97 (55%), Gaps = 1/97 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 + + AP+F+ LR G +FEC V+ P P I W + II+ S D+Q++Y + Sbjct: 3570 QSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHY-RN 3628 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 V L I + +PEDAGT+ C A N+ G ++T L V Sbjct: 3629 GVCRLTISQAYPEDAGTYACTATNSVGTVNTTATLEV 3665 Score = 70.9 bits (166), Expect = 4e-10 Identities = 50/216 (23%), Positives = 92/216 (42%), Gaps = 13/216 (6%) Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYEN 1531 ++ KI++P PL + + C G P P VTW++DG ++ + T++ Sbjct: 1347 QKPKIEAPVFTSPLSDAIIQEGSRFTFMCHVTGTPVPVVTWFKDGISIQNNPDYQTTFDQ 1406 Query: 1532 RX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQ-----KH 1584 Y C A N G ETS + +++ +P +S + Sbjct: 1407 GLCTLTIEETFAEDSAKYTCKAINAAGSAETSACLSVKETEPEEQLSPPTFVKLLEPGSA 1466 Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G + +EG P P V W+KN ++N +Y IT ++++ ++ ++YT Sbjct: 1467 REGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYNNGEAILKFDKVSLEDKAEYT 1526 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKP-EGPVIMREIS 1679 +A+N G + +L V P +P E P + +S Sbjct: 1527 CKATNELGVAQSTASLTV--TPLEPTEAPKFILPLS 1560 Score = 70.1 bits (164), Expect = 6e-10 Identities = 38/97 (39%), Positives = 50/97 (51%), Gaps = 1/97 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 EEQ P FV+ L P +G+ QF C+VEG P P + WF+ I S D+ + Y++ Sbjct: 1449 EEQLSPPTFVKLLEPGSAREGAGFQFYCKVEGNPLPTVQWFKNYECIDNSPDYVITYNNG 1508 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 A L +V ED +TC A N G A ST L V Sbjct: 1509 E-AILKFDKVSLEDKAEYTCKATNELGVAQSTASLTV 1544 Score = 61.7 bits (143), Expect = 2e-07 Identities = 41/195 (21%), Positives = 85/195 (43%), Gaps = 9/195 (4%) Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRX 1533 K + P P+ + N D+ L I G P P++TW ++G++L+ + N+ Sbjct: 2085 KTRPPKFITPVMGKIVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKV 2144 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592 Y C A N+ G+ ++ + +++ + ++ Q K GD ++ Sbjct: 2145 SVVIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIM 2204 Query: 1593 TAVIEGIPPPEVIWYKNG---NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + G P P V WYK+G + DK I + + + I++ + + S ++ + A N Sbjct: 2205 EVEVTGTPDPTVTWYKDGVPIGEALGDKA-RIRSMGNSHTLVIEKAELNMSGRFMVRAVN 2263 Query: 1650 TAGTSSVEVTLKVYD 1664 + G + + V++ Sbjct: 2264 SGGEAQSIADIAVFE 2278 Score = 61.3 bits (142), Expect = 3e-07 Identities = 48/184 (26%), Positives = 81/184 (44%), Gaps = 8/184 (4%) Query: 1207 LVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 +V N D L + + T ++TW K + ++ + D K +++I+ T DD Sbjct: 2099 IVDQNVDVVLEGIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSVVIKNATIDDAGR 2158 Query: 1266 YTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 YTC ++ A ST L V FPP + +K+G V + V+ P P W Sbjct: 2159 YTCTAVNEAGKAISTADLVVRKTVFPPVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTW 2218 Query: 1322 IVNSKIIKKCKHTKPSIDS--KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 + I + K I S S +L I+K E +G + +R N+ G A ++ + + Sbjct: 2219 YKDGVPIGEALGDKARIRSMGNSHTLVIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFE 2278 Query: 1380 KPSP 1383 P+P Sbjct: 2279 -PTP 2281 Score = 54.8 bits (126), Expect = 2e-05 Identities = 26/92 (28%), Positives = 44/92 (47%) Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 +++ PPP ++W KNG +EN +Y + + + I + + Y A+N+ GT Sbjct: 3598 IVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTISQAYPEDAGTYACTATNSVGTV 3657 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + TL+V PS G + R SV+ E Sbjct: 3658 NTTATLEVPGVPSHMYGTYRQLKTGRRSVSPE 3689 Score = 51.2 bits (117), Expect = 3e-04 Identities = 49/166 (29%), Positives = 78/166 (46%), Gaps = 19/166 (11%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 PP+ IT + + V++ E + G + W K+G +++ S+ +Q+ D K + Sbjct: 2088 PPKFITPVMGKIVDQNVDVVLE-GIVDGQPTPEITWTKNGEQLRESSGVQIHFDRNKVSV 2146 Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTVEE---PSINFTLRLPEFILVPANTDAYL 1216 I + +DDAG Y+C E G + TA L V + P + F RL + +V + Sbjct: 2147 VIKNATIDDAGRYTCTAVNEAGKAISTADLVVRKTVFPPV-FGRRL-QAQVVKKGDRVIM 2204 Query: 1217 TVEI---PDETLDVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRK 1257 VE+ PD T VTWYK I + +K + S TL+I K Sbjct: 2205 EVEVTGTPDPT--VTWYKDGVPIGEALGDKARIRSMGNSHTLVIEK 2248 Score = 48.4 bits (110), Expect = 0.002 Identities = 62/263 (23%), Positives = 104/263 (39%), Gaps = 21/263 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATL 568 P+F +L+ + G V E +V G P P +TW++ I + D N TL Sbjct: 2185 PVFGRRLQAQVVKKGDRVIMEVEVTGTPDPTVTWYKDGVPIGEALGDKARIRSMGNSHTL 2244 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM--TV--XXXXXXXXXXX 624 VI + +G F A N+ G A S ++ V P D E+ TV Sbjct: 2245 VIEKAELNMSGRFMVRAVNSGGEAQSIADIAVFEPTPDTMVEVVKTVVFEDVRKHETLTS 2304 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI---AWLFKGEEIVPDENIS 681 AD + T K + + E S + ++ + +I + K E VP+ + Sbjct: 2305 AADKVSSTVSTIPKPVEIPKIPESSHVSSRSEFTSMTKQEISKESKTMKFEHTVPEIPMP 2364 Query: 682 ------VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG-EKEP 734 + +E+D + +I KK +E +++++ V KIK G E P Sbjct: 2365 RVPTPVLKLETDYQICQPSSEIIQEKKVEETGIETSSISKQSSLQY-FVKKIKEGDEPVP 2423 Query: 735 PQVIE-----PLKSMIVRQGESV 752 P + E P+K + ++ E V Sbjct: 2424 PPLKETTIPVPIKPEVYKKFEEV 2446 Score = 47.2 bits (107), Expect = 0.005 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 1/87 (1%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 + +A P+FI + I V K V P P+I W +N II S ++ Sbjct: 3570 QSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNG 3629 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAG 913 L I+ E D+G Y C A+NS G Sbjct: 3630 VCRLTISQAYPE-DAGTYACTATNSVG 3655 Score = 42.3 bits (95), Expect = 0.14 Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 3/93 (3%) Query: 1107 PEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P IT L+N V G A FE I ++ + W K+G I+ SN QL +L I Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYRNGVCRLTI 3635 Query: 1166 YDCDLDDAGEYSCEVGNSKCT--AILTVEEPSI 1196 +DAG Y+C NS T T+E P + Sbjct: 3636 SQAYPEDAGTYACTATNSVGTVNTTATLEVPGV 3668 Score = 39.9 bits (89), Expect = 0.75 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 10/109 (9%) Query: 720 SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779 S P K+ P I PL+++ V G+ V P P I W KN + ++ Sbjct: 3561 STPGSTKVLQSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIE--- 3617 Query: 780 TKSDGDTH------SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 +D H +TI + +D G Y A NS G T+A + V Sbjct: 3618 NSNDYQLHYRNGVCRLTISQAYP-EDAGTYACTATNSVGTVNTTATLEV 3665 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P FI L++ V A E + SE +++W ++G II+ N Y R + +L Sbjct: 3576 PMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIE-NSNDYQLHYRNGVCRLT 3634 Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVT-VVELP 1106 I D G Y+C + T T +E+P Sbjct: 3635 ISQAYPEDAGTYACTATNSVGTVNTTATLEVP 3666 Score = 36.3 bits (80), Expect = 9.2 Identities = 21/102 (20%), Positives = 40/102 (39%), Gaps = 4/102 (3%) Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE 1530 + ++ ++P PL+NI + + CI P P + W ++G+ ++ + + Y Sbjct: 3568 VLQSSARAPMFITPLRNIAVVSGQPAKFECIVQSEPPPNILWSKNGRIIENSNDYQLHYR 3627 Query: 1531 NRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 N Y C A N G V T+ + + P Sbjct: 3628 NGVCRLTISQAYPEDAGTYACTATNSVGTVNTTATLEVPGVP 3669 >UniRef50_UPI00015B62AD Cluster: PREDICTED: similar to GA13389-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA13389-PA - Nasonia vitripennis Length = 1541 Score = 176 bits (428), Expect = 6e-42 Identities = 111/392 (28%), Positives = 189/392 (48%), Gaps = 16/392 (4%) Query: 1381 PSPPGKPNIL--EIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 P+PPGKP ++ E D+ + I W+ + G S II Y VE++++ + W+ + T Sbjct: 60 PAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLCT 119 Query: 1437 --QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNITT 1493 + ++ L+ Y+FR A N + +S+ SE ++ V ++ T +P + L++ Sbjct: 120 FPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVA 179 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549 E E I+ G P PKV+W++DG ++ +T T + K Sbjct: 180 LEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIK 239 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 C A N G + T + I+ P + + + + + G+ + A G PPP + WY Sbjct: 240 CSATNRAGHISTRAKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYH 299 Query: 1609 NGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 NG + D+ +N + + ++++I++ KR +YTI A N G + V D+P+ Sbjct: 300 NGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTVTDRPA 359 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 P ++ + R SVT+ WK P DDGG ++ Y IE + + W+K A R + T Sbjct: 360 APGKTIVTSTLGR-SVTLAWKEPDDDGGCKIGTYIIEYYRIGWDVWLK-AVTCRQI-TAT 416 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 + L E EY FRV A+NP G S+ E I+ Sbjct: 417 LNDLIEGSEYRFRVKAENPYGVSDPSEESDII 448 Score = 112 bits (269), Expect = 1e-22 Identities = 69/249 (27%), Positives = 113/249 (45%), Gaps = 7/249 (2%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284 V+W+K I + + + +D K LII++ + DD+ E C + +T+ K+ ++ Sbjct: 199 VSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIKCSATNRAGHISTRAKL-MI 257 Query: 1285 EFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDS 1340 E PP + YE ++G + L P P+ W N +II +H SI Sbjct: 258 EAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITD 317 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 L I+ + D G Y +R N G VT+ D+P+ PGK + S+ + Sbjct: 318 NETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTVTDRPAAPGKTIVTSTLGRSVTLA 377 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 W EP++ G I Y++EY I W+ + ++ +L S YRFR A N Sbjct: 378 WKEPDDDGGCKIGTYIIEYYRIGWDVWLKAVTCRQITATLNDLIEGSEYRFRVKAENPYG 437 Query: 1461 ISDASETTE 1469 +SD SE ++ Sbjct: 438 VSDPSEESD 446 Score = 67.3 bits (157), Expect = 4e-09 Identities = 56/229 (24%), Positives = 98/229 (42%), Gaps = 16/229 (6%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 +F+ + ++ E S P+ + ++ P+ L+ + +GE G Sbjct: 135 QFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGT 194 Query: 762 PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 P P ++W K+ + + + T G S+ I++ + DEG A N G T Sbjct: 195 PLPKVSWFKDGFEIFSSRRTMITTDSGK--SVLIIQRTSIDDEGEIKCSATNRAGHISTR 252 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPS 876 A + +E P ++++ + E+G TI+L A P PSITWY N EII Sbjct: 253 AKLMIEAPPHVRLP-----RQYEDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVD 307 Query: 877 ETITQNFDG-ENIELVITNVDSE-IDSGDYKCVASNSAGKSSHGARVTI 923 + NF+ + E ++ D++ D G+Y A N G+ VT+ Sbjct: 308 Q--RHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLVTV 354 Score = 64.9 bits (151), Expect = 2e-08 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P+ P +V+ + RSVTL W EP+ +GG I YIIE+ + W K VT Sbjct: 358 PAAPGKTIVTSTLGRSVTLAWKEPDDDGGCKIGTYIIEYYRIGWDVWLKAVTCRQIT--A 415 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + ++ E E FR+ AEN GVS P+E + Sbjct: 416 TLNDLIEGSEYRFRVKAENPYGVSDPSEESDI 447 Score = 63.7 bits (148), Expect = 5e-08 Identities = 91/409 (22%), Positives = 163/409 (39%), Gaps = 39/409 (9%) Query: 1666 PSKPEGPVIM---REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P+ P P+++ + + V I W+ +GG + Y +E + + W++ A V Sbjct: 60 PAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLCT 119 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXXXXXX 1778 + L Y FR+ AQN +G SE E S+P+ + +TA P Sbjct: 120 FPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVA 179 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEG------KKWKXXXXXXXXXARIQKLSIN 1832 ++ E G+P+ KV ++G ++ IQ+ SI+ Sbjct: 180 LEGEQAEFEVI----YAGTPL--PKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSID 233 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 + + A N G + + I + P Q + ++ E ++ LK T N Sbjct: 234 DEGEIKCSATNRAG-HISTRAKLMIEAPPHVRLPRQYEDGLLFEQ-GETIRLKAT----N 287 Query: 1893 GGSP---ITNYII-EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 GG P IT Y E V + + +T ++ + I++ K +D + I A N +G Sbjct: 288 GGRPPPSITWYHNGEIIIVDQRHNFESITDNETILK--IQDAKRQDRGEYTIRAINKLG- 344 Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 E + L P+ P + +G ++ + +W P+ DGG + Y I + Sbjct: 345 ----EDVASFLVTVTDRPAAPGKTIVTSTLGRSVTL-AWKEPDDDGGCKIGTYIIEYYRI 399 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 +W++ V + + DL E Y R+ A N G+S+P E + Sbjct: 400 GWDVWLKA--VTCRQITATLNDLIEGSEYRFRVKAENPYGVSDPSEESD 446 Score = 62.1 bits (144), Expect = 2e-07 Identities = 53/184 (28%), Positives = 77/184 (41%), Gaps = 14/184 (7%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 EG E P P ++W G EI + +S SVL I EG Sbjct: 181 EGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGK----SVLIIQRTSIDDEG 236 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763 A NR G S L I+ PP V P + ++ QGE++ L A G P Sbjct: 237 EIKCSATNRAGHISTRAKLMIEA----PPHVRLPRQYEDGLLFEQGETIRLKATNGGRPP 292 Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P+ITW N + + + +S D +I ++ K +D G YT++A N G S ++ Sbjct: 293 PSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTIRAINKLGEDVASFLV 352 Query: 821 TVEE 824 TV + Sbjct: 353 TVTD 356 Score = 54.0 bits (124), Expect = 4e-05 Identities = 44/178 (24%), Positives = 83/178 (46%), Gaps = 11/178 (6%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 + ++A+N+ G++E S + T + + P F ++ E + P Sbjct: 136 FRIRAQNALGLSEPSELSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGTP 195 Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVI-TNVDSEIDSGDYKCVASNSAGKSSHG 918 +P ++W+++ EI S T+ G+++ ++ T++D D G+ KC A+N AG S Sbjct: 196 LPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSID---DEGEIKCSATNRAGHISTR 252 Query: 919 ARVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973 A++ I+ V + + E+G+T+ L+ S WYHN EI +D R Sbjct: 253 AKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYHN-GEIIIVDQR 309 Score = 53.6 bits (123), Expect = 6e-05 Identities = 32/97 (32%), Positives = 47/97 (48%), Gaps = 1/97 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S AP F LR +G +FE G P P+++WF+ I S+ M D + Sbjct: 165 SSAPRFDLDLRDCVALEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSSRR-TMITTDSGKS 223 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L+I+ +D G C A N AG S+ +L++EAP Sbjct: 224 VLIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAP 260 Score = 50.4 bits (115), Expect = 5e-04 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 1965 VPSPPTAPLEI---RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 +P+PP P+ I ++V W +GG+ ++GY++ R + W+ V Sbjct: 59 LPAPPGKPILIPGEEDAQPDVVGIRWERSPSNGGSAIIGYHVEHRKMGSPHWVRSAPVLC 118 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + + L Y RI A+N +GLSEP E +P V Sbjct: 119 TFPELTLSGLEPGWRYQFRIRAQNALGLSEPSELSDPLSV 158 Score = 49.2 bits (112), Expect = 0.001 Identities = 50/183 (27%), Positives = 73/183 (39%), Gaps = 17/183 (9%) Query: 1120 KGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 +G +A FE+ + G L V WFKDG EI S +T D K L I +DD GE Sbjct: 181 EGEQAEFEV-IYAGTPLPKVSWFKDGFEIFSSRRTMITTDSGKSVLIIQRTSIDDEGEIK 239 Query: 1178 C----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYK 1231 C G+ A L +E P + + + +L L +TWY Sbjct: 240 CSATNRAGHISTRAKLMIEAPPHVRLPRQYEDGLLFEQGETIRLKATNGGRPPPSITWYH 299 Query: 1232 KKSVI--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 +I + F I+D + L I+ D+ EYT ++ KL +V F Sbjct: 300 NGEIIIVDQRHNFESITD-NETILKIQDAKRQDRGEYT-----IRAINKLGEDVASFLVT 353 Query: 1290 IVD 1292 + D Sbjct: 354 VTD 356 Score = 44.4 bits (100), Expect = 0.035 Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 12/192 (6%) Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVVWERDG-EIIKP 1058 + D + T+ + P F L+D E + A EV + V W +DG EI Sbjct: 152 LSDPLSVTLQRTASSAPRFDLDLRDCVALEGEQAEFEVIYAGTPLPKVSWFKDGFEIFSS 211 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEI-ITRLQ 1114 ++ + + L I+ TS+ DEGE C + + T ++E PP + + R Sbjct: 212 RRTMITTDSGKSV--LIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAPPHVRLPRQY 269 Query: 1115 NQKVNKGNKATFEIELTKG---DALVRWFKDGSEIQF-SNHIQLTIDGKKQKLKIYDCDL 1170 + T ++ T G + W+ +G I H +I + LKI D Sbjct: 270 EDGLLFEQGETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKR 329 Query: 1171 DDAGEYSCEVGN 1182 D GEY+ N Sbjct: 330 QDRGEYTIRAIN 341 Score = 44.4 bits (100), Expect = 0.035 Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 10/151 (6%) Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-----E 647 S + LI++ D E+ A ++ PP + P+ QY D + Sbjct: 220 SGKSVLIIQRTSIDDEGEIKCSATNRAGHISTRAKLMIEAPPHV-RLPR-QYEDGLLFEQ 277 Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G I L+ P P I W GE I+ D+ + +D ++LKI + K+ G Sbjct: 278 GETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNE---TILKIQDAKRQDRGE 334 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 YT+ A+N+ GE ++ + P + I Sbjct: 335 YTIRAINKLGEDVASFLVTVTDRPAAPGKTI 365 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/67 (31%), Positives = 29/67 (43%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T++ + G P P ITW+ II Q DN L I++ +D G +T Sbjct: 278 GETIRLKATNGGRPPPSITWYHNGEIIIVDQRHNFESITDNETILKIQDAKRQDRGEYTI 337 Query: 584 VAKNAAG 590 A N G Sbjct: 338 RAINKLG 344 >UniRef50_UPI0000ECA094 Cluster: eEF1A2 binding protein; n=3; Gallus gallus|Rep: eEF1A2 binding protein - Gallus gallus Length = 843 Score = 174 bits (424), Expect = 2e-41 Identities = 116/480 (24%), Positives = 201/480 (41%), Gaps = 10/480 (2%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543 V K L ++ E EL+C TW++DG KL + + Sbjct: 51 VSKHLNDVRVLKGEPTELSCAVNRHDLTG-TWFKDGLKLTSMDGVSLEKEGLVHKLVISK 109 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPV---ITISN-EDIKQKHKVGDEWLVTAVIEGI 1599 + + G+++T + ++ P I + N + K G++ ++ EG Sbjct: 110 VEDIHAGKYRFEAGDIKTEASIFVEDPPQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGR 169 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P W K+ +L +D + + +++ I +R Y + N +G +++ Sbjct: 170 LPVRATWLKDKIELGDDSRVRVDKTDTFTMLSISNAERKDCGDYKVRLKNDSGILDIDLK 229 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 ++V DKP P GP+ + E S VTI+W PP DDGG + Y IEK + + W+ V + Sbjct: 230 VEVIDKPQPPAGPMKIVESSANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGET 289 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 R T+ K+ ++ Y FRV A N G S+ALES+ +V T + Sbjct: 290 PRSCTTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVV--TISKGSPGAPDPPEIIGV 347 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KW--KXXXXXXXXXARIQKLSINTTYQ 1836 +++ I+W + G S I Y V+ ++ G W +I L Y+ Sbjct: 348 SKDTITISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYE 407 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 F + A N G + + TPP + R+ ++ + + SVTL W PE+ GS Sbjct: 408 FCVAAVNASGIGDMSAPSQSVFARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSA 467 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + Y +E ++ SWTK + ++ ++ K R+ A N G TE ++ Sbjct: 468 VEGYNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEA 527 Score = 138 bits (333), Expect = 2e-30 Identities = 160/669 (23%), Positives = 258/669 (38%), Gaps = 39/669 (5%) Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 L + +V KG + + D WFKDG ++ + + L +G KL I + Sbjct: 55 LNDVRVLKGEPTELSCAVNRHDLTGTWFKDGLKLTSMDGVSLEKEGLVHKLVISKVEDIH 114 Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP--ANTDAYLTVEIPDE---TLDV 1227 AG+Y E G+ K A + VE+P + L VP A + ++IP E + Sbjct: 115 AGKYRFEAGDIKTEASIFVEDPPQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGRLPVRA 174 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVE 1285 TW K K + D + + L I D +Y L + LKVEV++ Sbjct: 175 TWLKDKIELGDDSRVRVDKTDTFTMLSISNAERKDCGDYKVRLKNDSGILDIDLKVEVID 234 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVD--YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS- 1342 P + +DVT+ + +P +I+ + + K +S Sbjct: 235 KPQPPAGPMKIVE-SSANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSC 293 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADV--EMNVTILDKPSP--PGKPNILEIDSSSIN 1398 + T KVE + +++R N G +D V + K SP P P I+ + +I Sbjct: 294 TTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIGVSKDTIT 353 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAV 1456 I W P G+S I Y+V+ +++ + W+ V + + + I +LK Y F AV Sbjct: 354 ISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYEFCVAAV 413 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT-----CIFGGVPQP 1511 N I D S ++ V P + LK +T N + LT G + Sbjct: 414 NASGIGDMSAPSQ--SVFARDSTTPPGKVRDLK-MTINDNTSVTLTWNAPEAKEGSAVEG 470 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQQ 1569 R L K Y + A ND G E + + + Sbjct: 471 YNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEACTE 530 Query: 1570 KPVITISNEDIKQKH-------KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 +S I K K G+ V E P + W K+G L + I+ Sbjct: 531 AVPRVVSPRFIIDKRVKNFLVIKAGNTIRVDIPYEAPPDSVLTWLKDGVPLPS--RAKIS 588 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIE-ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 T++ TS + IK + + S YT+E S T + ++V D P +P GP+ +RE Sbjct: 589 TQDDTSQLLIKAAQFTDSGIYTVELTSGTGKRETFSFQVQVTDIP-QPPGPIELRENVPN 647 Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 VT+ W+P + Y + K E W + D+ + K+ +Y FRV Sbjct: 648 IVTVTWEPSTSEKWESNLFYTVLKRESRKGLWHVIGDLIY-TNKFTYTKVIPGRDYYFRV 706 Query: 1742 IAQNPVGFS 1750 +A+N +G S Sbjct: 707 VAKNHLGSS 715 Score = 120 bits (290), Expect = 3e-25 Identities = 107/468 (22%), Positives = 196/468 (41%), Gaps = 25/468 (5%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+K+G KL + ++ + + I +++ H+ KY EA G E ++ V D Sbjct: 81 WFKDGLKLTSMDGVSLEKEGLVHKLVISKVEDIHAGKYRFEA----GDIKTEASIFVEDP 136 Query: 1666 PSKPE----GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 P E + +++ + K P + + +K E ++ ++V D Sbjct: 137 PQVDEILLKNLTSVPTVAKAGEKVVIKIPFEGRLPVRATWLKDKIELGDDSRVRVDKTDT 196 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT-ALDVPSXXXXXXXXXXID 1780 ++C ++V +N G + I +K +D P Sbjct: 197 FTMLSISNAERKDCGD-YKVRLKNDSGILD------IDLKVEVIDKPQPPAGPMKIVESS 249 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQF 1837 V I W P + +GG P+ +Y +E +Q GK W K+ + +Y F Sbjct: 250 ANDVTIQWNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSCTTFTTSKVEQDMSYYF 309 Query: 1838 RIYARNEIGTSLPYTSDDKITIGK-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 R+ A N GTS SD+ +TI K + P P VS+ T +T+ W P G S Sbjct: 310 RVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIGVSKDT---ITISWKTPRRAGSSR 366 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQ 1955 I+ YI++ + + +W + +V + + I ++K+ + F ++A N G+ + SQ Sbjct: 367 ISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYEFCVAAVNASGIGDMSAPSQ 426 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 SV + +T P L++ + + V +W PE G+ + GYN+ +R W + Sbjct: 427 SV-FARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSAVEGYNVEMRSSNNLSWTK 485 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + T + ++ L TY +R+ A N+ G E E + + +P Sbjct: 486 CNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPGEATELEACTEAVP 533 Score = 99 bits (238), Expect = 7e-19 Identities = 100/452 (22%), Positives = 186/452 (41%), Gaps = 27/452 (5%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTS----SVEVTLKVYDKPSKPEGPVIMREI 1678 T + ++++ S + + A N GTS S EV P P+ P I+ + Sbjct: 289 TPRSCTTFTTSKVEQDMSYYFRVRAVNAEGTSDALESDEVVTISKGSPGAPDPPEIIG-V 347 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 S++++TI WK P G ++ Y ++K + + W+ V V + I L + +Y Sbjct: 348 SKDTITISWKTPRRAGSSRISGYIVQKRKMGSMTWVPVNSVPVADKKLKITDLKKGLQYE 407 Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 F V A N G + V P DN SV +TW E GS Sbjct: 408 FCVAAVNASGIGDMSAPSQSVFARDSTTPPGKVRDLKMTINDNTSVTLTWNAPEAKEGSA 467 Query: 1799 IIDYKVEIKQEGK-KWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 + Y VE++ W +++ L TY R+ A N+ G T + Sbjct: 468 VEGYNVEMRSSNNLSWTKCNIFPIETTTYKVKGLQTKGTYFLRVRAINDCGPG-EATELE 526 Query: 1856 KIT--IGKTLTP----PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 T + + ++P + +NF+V ++ + T++ P + ++ + + Sbjct: 527 ACTEAVPRVVSPRFIIDKRVKNFLVIKAGN---TIRVDIPYEAPPDSVLTWLKDGVPLPS 583 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969 ++ KI T + + I+ + D I+ + + G E+ S +++ +P PP Sbjct: 584 RA--KISTQDDT-SQLLIKAAQFTDSGIYTVELTSGTG---KRETFSFQVQV-TDIPQPP 636 Query: 1970 TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029 P+E+R NIV +W + L Y + R+ K +W +G + + T KF Sbjct: 637 -GPIELRENVPNIVTVTWEPSTSEKWESNLFYTVLKRESRKGLWHVIGDL-IYTNKFTYT 694 Query: 2030 DLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + Y R+ A+N +G S P ++ +P+++ Sbjct: 695 KVIPGRDYYFRVVAKNHLGSSCPSDTVQPWRI 726 Score = 83.8 bits (198), Expect = 5e-14 Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 18/240 (7%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 IK G+ + + + Y+A P W+ + + K S ++ L IK + TD+GIY Sbjct: 552 IKAGNTIRVDIPYEAPPDSVLTWLKDG--VPLPSRAKISTQDDTSQLLIKAAQFTDSGIY 609 Query: 1359 KLRLENNCGHADV-EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + L + G + V + D P PPG + E + + + W+ + + ++Y V Sbjct: 610 TVELTSGTGKRETFSFQVQVTDIPQPPGPIELRENVPNIVTVTWEPSTSEKWESNLFYTV 669 Query: 1418 EYQEIDTTEWISVKNITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E W + ++ T + + + Y FR A N + S S+T + +++ K Sbjct: 670 LKRESRKGLWHVIGDLIYTNKFTYTKVIPGRDYYFRVVAKNHLGSSCPSDTVQPWRIRKP 729 Query: 1477 --------------TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + Q P PLK + ++C GG P PKVTWY+DGK L Sbjct: 730 KADIQVRPQRYKGVNQNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDL 789 Score = 69.3 bits (162), Expect = 1e-09 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 7/149 (4%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I N + KD +++ +N G+ L + + ++K P PP P++I +N V Sbjct: 202 ISNAERKDCGDYKVRLKNDSGI-LDIDLKVEVIDK----PQPPAGPMKIVESSANDVTIQ 256 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ DGG P+ Y I + V K+ W+ VG+ + F + ++ +Y R+ A N Sbjct: 257 WNPPKDDGGKPVQNYIIEKQQVGKSDWVAVGETPRSCTTFTTSKVEQDMSYYFRVRAVNA 316 Query: 2047 IGLSEPLESDEPFKVIPGEGSHADEEPGE 2075 G S+ LESDE + +GS +P E Sbjct: 317 EGTSDALESDEVVTI--SKGSPGAPDPPE 343 Score = 58.4 bits (135), Expect = 2e-06 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTH 787 + +PP+ + PLK +V G +S V G+P P +TW K+ K + P+ +D Sbjct: 745 QNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVC 804 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 S+ IL K DEG YT++A N G A + A +T++ Sbjct: 805 SLVILGVSKA-DEGDYTVEATNESGRAFSRASLTIK 839 Score = 52.8 bits (121), Expect = 1e-04 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q+ P F+ L+P GS + C V G+P P++TW++ + + + +D V Sbjct: 745 QNQPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSY-FGTNDFGV 803 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +LVI V D G +T A N +G A S L ++ Sbjct: 804 CSLVILGVSKADEGDYTVEATNESGRAFSRASLTIK 839 Score = 50.0 bits (114), Expect = 7e-04 Identities = 23/76 (30%), Positives = 39/76 (51%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G PPP+V WYK+G L N+ Y T + I + ++ YT+E Sbjct: 763 GSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVCSLVILGVSKADEGDYTVE 822 Query: 1647 ASNTAGTSSVEVTLKV 1662 A+N +G + +L + Sbjct: 823 ATNESGRAFSRASLTI 838 Score = 46.4 bits (105), Expect = 0.009 Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 +PP F+ + V ++ V +P P +TWY++ + +S + + D L Sbjct: 747 QPPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDLSNNPSYFGTNDFGVCSL 806 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 VI V S+ D GDY A+N +G++ A +TI Sbjct: 807 VILGV-SKADEGDYTVEATNESGRAFSRASLTI 838 Score = 46.0 bits (104), Expect = 0.011 Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K V GS+ + C + P P + W G+++ N S +D + C Sbjct: 748 PPRFLVPLKPHVVTTGSECRMSCAVGGHPPPKVTWYKDGKDL--SNNPSYFGTNDFGV-C 804 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 S L I V K EG YTV A N G A L IK Sbjct: 805 S-LVILGVSKADEGDYTVEATNESGRAFSRASLTIK 839 Score = 38.3 bits (85), Expect = 2.3 Identities = 17/73 (23%), Positives = 35/73 (47%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 ++++ G ++ + P +TW K+ P+ + S D S ++K + D G+Y Sbjct: 550 LVIKAGNTIRVDIPYEAPPDSVLTWLKDGVPLPSRAKISTQDDTSQLLIKAAQFTDSGIY 609 Query: 804 TLKAENSEGIAET 816 T++ + G ET Sbjct: 610 TVELTSGTGKRET 622 >UniRef50_Q8T104 Cluster: Projectin-like protein; n=1; Bombyx mori|Rep: Projectin-like protein - Bombyx mori (Silk moth) Length = 1072 Score = 174 bits (424), Expect = 2e-41 Identities = 109/397 (27%), Positives = 187/397 (47%), Gaps = 16/397 (4%) Query: 1377 ILDKPSPPGKPNILEI----DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 + +P+PPGKP I+ I + ++I + W + G + + Y VE + +TEWI Sbjct: 52 VTGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAP 111 Query: 1433 --ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPLK 1489 + + + + L+ Y+FR A+N+V S+ SE ++ V + Q P V K L+ Sbjct: 112 PIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 171 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXX 1545 ++T N+ +E F G+P P + W++D ++ +TA T E+ Sbjct: 172 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 231 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNE-DIKQKHKVGDEWLVTAVIEGIPPPEV 1604 KC A N G T + ++ P + + + +++ + + I G P P + Sbjct: 232 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 291 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W +G+ + D I+ K SV++I KRS +Y I+A N G + + V Sbjct: 292 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 351 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 P P + R++ + SVT++W+PP DDGG ++ Y +E + N W+K A R Sbjct: 352 PPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTN 409 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVI 1760 + L E EY FR+ A++P G S + ES P+ I Sbjct: 410 V-TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 445 Score = 79.8 bits (188), Expect = 8e-13 Identities = 58/259 (22%), Positives = 102/259 (39%), Gaps = 8/259 (3%) Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 IP T + W+K I + + + +D L+ + D+ E C + Sbjct: 190 IPSPT--IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 247 Query: 1280 KVEV-VEFPPKIVDYEREYR----IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 K + +E PK+ Y R+Y + + L P P EW + I Sbjct: 248 KARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 306 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + SI K + L I + +D G Y+++ +N G VT+ P PP ++ Sbjct: 307 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 366 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 S+ + W+ P + G + Y+VEY W+ KT ++ +L S Y+FR Sbjct: 367 KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIK 426 Query: 1455 AVNEVDISDASETTEYYKV 1473 A + +S S + ++ Sbjct: 427 AESPYGMSAPSSESSPVRI 445 Score = 66.9 bits (156), Expect = 6e-09 Identities = 43/129 (33%), Positives = 64/129 (49%), Gaps = 9/129 (6%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 +++I A+N IG T+ +T+ PP PRN V+ +SVTL W P +GG Sbjct: 329 EYQIQAKNIIGED---TAAFLVTV---TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 382 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954 + NYI+E+ W K +T + ++ E E FRI AE+ G+S P +ES Sbjct: 383 KVGNYIVEYYRTGWNVWLKAIT--SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 440 Query: 1955 QSVRLEKHA 1963 VR+ A Sbjct: 441 SPVRIPGRA 449 Score = 63.7 bits (148), Expect = 5e-08 Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 10/254 (3%) Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 +T L+P V L +E S V+TV + EPP+FI R +++T E Sbjct: 121 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSD-RASQEPPVFIKRLEDVTALEND 179 Query: 849 TIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 ++ + P P+I W++++ EI S T + ++ L + S D G+ KC Sbjct: 180 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS--DEGEIKCT 237 Query: 908 ASNSAGKSSHGARVTID-VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNK 964 A+N G + AR+ ++ K+ + + + E +T+ L+ T + +W H+ Sbjct: 238 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 297 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIR 1021 I D EI + D G + K+ ++T+ LV P+ R Sbjct: 298 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 357 Query: 1022 KLQDFEVKEKDVAI 1035 + +K V + Sbjct: 358 NVSVTRQVDKSVTL 371 Score = 62.5 bits (145), Expect = 1e-07 Identities = 50/198 (25%), Positives = 76/198 (38%), Gaps = 9/198 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K+ + E + IP P IAW EI ++ + Sbjct: 163 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES----T 218 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGES 751 SVL + EG A NR G A L ++ K P+ E ++ E+ Sbjct: 219 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE--DGLLYEINET 276 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAEN 809 + L +VG P PTI W + P+ T ++LK K D G Y ++A+N Sbjct: 277 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 336 Query: 810 SEGIAETSAVITVEEPTE 827 G + ++TV P + Sbjct: 337 IIGEDTAAFLVTVTAPPD 354 Score = 54.4 bits (125), Expect = 3e-05 Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 4/114 (3%) Query: 489 NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 +E D L V S+E P+F+++L + V+F G P P I WF+ Sbjct: 146 SELSDVLTVSSDRASQEP---PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 202 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 I S+ + D++ + L+ ++ P D G C A N G A + L +EA Sbjct: 203 EIFSSRRTAIT-TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 255 Score = 52.4 bits (120), Expect = 1e-04 Identities = 58/238 (24%), Positives = 99/238 (41%), Gaps = 16/238 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEAS---LPIVLKIKT--GEKEPPQVIEPLKSMIVRQG 749 L +T ++ + + V A+N G ++ L VL + + +EPP I+ L+ + + Sbjct: 119 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 178 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 + V G P PTI W K++ + + + S ++L ++ DEG A Sbjct: 179 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 238 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSIT 865 N G A T A + +E A P L R E + + TI L + P P+I Sbjct: 239 TNRGGHAVTKARLCLE------AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 292 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + I + I + + L I + D G+Y+ A N G+ + VT+ Sbjct: 293 WRHDGHPIITDDRIEISITPKFSVLKIHSA-KRSDRGEYQIQAKNIIGEDTAAFLVTV 349 Score = 50.0 bits (114), Expect = 7e-04 Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 6/111 (5%) Query: 1966 PSPPTAPLEIRMVGS---NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 P+PP P I ++ N + W DGGAPL GY + + T W+ V Sbjct: 56 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 115 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 + + L H Y R+ A N++G S E + V+ A +EP Sbjct: 116 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD---VLTVSSDRASQEP 163 Score = 46.4 bits (105), Expect = 0.009 Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 9/144 (6%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I + K D ++I A+N +G E + L P PP R V ++ + Sbjct: 319 IHSAKRSDRGEYQIQAKNIIG-----EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL-D 372 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P DGG + Y + +W++ + + DL E Y RI A + Sbjct: 373 WEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESP 430 Query: 2047 IGLSEPLESDEPFKVIPGEGSHAD 2070 G+S P P + IPG D Sbjct: 431 YGMSAPSSESSPVR-IPGRAIDMD 453 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 5/86 (5%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 I L+ +V P P I W G I+ D+ I ++I SVLKI + K+ G Y + Sbjct: 277 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF----SVLKIHSAKRSDRGEYQI 332 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQ 736 A N GE + ++ + T +PP+ Sbjct: 333 QAKNIIGEDTAAFLVTV-TAPPDPPR 357 Score = 43.6 bits (98), Expect = 0.061 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Query: 1865 PPSQPRNF-VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVH 1923 PP +P+ ++S+ ++TLKW +GG+P+ Y +E + W + Sbjct: 58 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 117 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 E + ++ + FR++A N VG S +E V Sbjct: 118 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDV 151 Score = 42.3 bits (95), Expect = 0.14 Identities = 46/193 (23%), Positives = 74/193 (38%), Gaps = 19/193 (9%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNKYDFEKRGHIRKL 1074 P FI++L+D E D V + + + W +D EI ++ ++ + L Sbjct: 164 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--L 221 Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT--- 1131 DEGE C + A VT L E +L+ + + +EI T Sbjct: 222 LFHQILPSDEGEIKCTATNRGGHA-VTKARLCLEAAPKLRYPRQYEDG-LLYEINETIFL 279 Query: 1132 ------KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VG 1181 K + W DG I + I+++I K LKI+ D GEY + +G Sbjct: 280 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 339 Query: 1182 NSKCTAILTVEEP 1194 ++TV P Sbjct: 340 EDTAAFLVTVTAP 352 >UniRef50_UPI0000D57997 Cluster: PREDICTED: similar to CG33519-PB; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG33519-PB - Tribolium castaneum Length = 4089 Score = 173 bits (422), Expect = 3e-41 Identities = 216/904 (23%), Positives = 356/904 (39%), Gaps = 93/904 (10%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ V G L C++ A P+ ++ W + + EN+ + + Y V K Sbjct: 2061 PQNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETYRLVFKKAL 2120 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 + EG Y VVA N GE+S LK T E P +I L V + + + + Sbjct: 2121 LS--DEGYYKVVAKNSLGESSSEARLKAVT---EKPTIITGLSDDQVEHTKEISVMVRAD 2175 Query: 760 GNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 G P+P I W N KP+ + + +D S + D G+Y A N +G A Sbjct: 2176 GLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGIYKAIAANVQGEA 2235 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEII 873 +TSA IT+ + PP F + + V E ++L A++ +P P++ WY+N E I Sbjct: 2236 DTSARITMVQT------PPTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPI 2289 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV--EKVTFV 931 T ++L I + DSG YK V N G+S+ V + ++ F+ Sbjct: 2290 DDERVKTSVLPDGTVKLNIEHARPS-DSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFL 2348 Query: 932 KHLQKSYETEEGKTVILECQT-SHTV-STKWYHN--KKEISGMDHREIIQEGRXXXXXXX 987 K K + G+T+ LE Q +H KW + +S H E+ +G+ Sbjct: 2349 KCF-KDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDC 2407 Query: 988 XXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE-I 1040 + G + V ++ E S + K T PEF+ +L V E EV+ + Sbjct: 2408 AKPE-NAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAV 2466 Query: 1041 NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDESCTA 1098 + W R+G E+I K+ E L + + +G Y I +E+ A Sbjct: 2467 GHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEA 2526 Query: 1099 E----VTVV--------ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSE 1145 E +TV+ E P + L++ ++G T +V W KDG Sbjct: 2527 ETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVP 2586 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFT 1199 + S+ I +T DGKK L+I + DAG YS ++ N S+ A + +FT Sbjct: 2587 LSPSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFMPPHFT 2646 Query: 1200 LRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 + +P DA + +V W K I++++K+ + D L + C Sbjct: 2647 QTFTDLQQLPGR-DAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNC 2705 Query: 1259 TEDDQCEY--TCVLLDAKSTTKLKVEVVE--------FPPKIVDYEREYRIKRGSDVTLL 1308 + DD Y + + + +EVV+ PP + + + +G Sbjct: 2706 SPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFT 2765 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCG 1367 +P+P EW N + + K D L I ++ D G Y ++ N G Sbjct: 2766 ACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEADLGKYSCKITNEYG 2825 Query: 1368 ----HADVEMN--------------VTILDK------PSPPGKPNIL-EIDSSSINICWD 1402 HA++ M+ T DK P P P I+ ++ + W Sbjct: 2826 GDICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCTLSWK 2885 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 G + Y +E E+ +W +V+ I ++NL+ Y+FR N+ I Sbjct: 2886 PSIPPGPRAPVTYQLEMCELPNGDWFTVRTGIRSCTCGVRNLEPFRDYKFRVRVENKYGI 2945 Query: 1462 SDAS 1465 SD S Sbjct: 2946 SDPS 2949 Score = 149 bits (362), Expect = 6e-34 Identities = 160/687 (23%), Positives = 296/687 (43%), Gaps = 46/687 (6%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-------LPTK 781 +G++E + I+ ++ + GE + P T TW K++KP+ + + + Sbjct: 836 SGDEERNRFIKTIRGADIEPGEKFTFEVALKSKP-DTFTWLKDDKPLDSNAIMLGRIQMR 894 Query: 782 SDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN------AEPPL 834 D++ + + P D G YT A G A SA++ V + T E + P Sbjct: 895 HSEDSYLYKLYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPE 954 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDGENIELV 891 F+ + ++ + E ++ + +V +P P + ++++ I+ S E I ++ D EL+ Sbjct: 955 FVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELL 1014 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 I V D+G+YKCVASN G+ S A + + E + K + + G+T + + Sbjct: 1015 IPEVQMS-DAGEYKCVASNKWGEDSCEATLKVTTEDLH--KDMPEGEILPPGETPEFQWK 1071 Query: 952 TSHTVSTKWYHNKKEISGMDHRE---IIQEGRXXXXXXXX-XXXXDVGVIKCIVK--DQE 1005 + K + G D + Q R G I C + Sbjct: 1072 -KDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVHG 1130 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP-KKNKY 1063 T LV + P I + ++ V A++E+++ V W +G+ I+ K K+ Sbjct: 1131 TVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYKF 1190 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTV-VELPPEIITRLQNQKVNK 1120 +E L I++ D G+Y C +E S TAE+T+ V+ PP++ ++++ + Sbjct: 1191 LYEDE-ETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPPKLRKKIEDVDAHA 1249 Query: 1121 G--NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 + EIE T +V ++KDG EI+ I++ + +K L I L D+G YS Sbjct: 1250 DLLLEIPVEIEGTPRPKVV-FYKDGKEIKKDERIKVVEENEKVVLVIEKTMLKDSGSYSI 1308 Query: 1179 EVGN-----SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 N S+ + +P I L + + + + +E E +V WYK Sbjct: 1309 VATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIESEPEA-EVKWYKDD 1367 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVD 1292 + I+ ++ + + D + L I D Y ++ + + + V V+ PKI Sbjct: 1368 AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDVKKAPKITK 1427 Query: 1293 YEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKV 1350 ++ + + VTL V +AFP+P+ +W ++ I + K +DS L IK+V Sbjct: 1428 GLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEV 1487 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTI 1377 + +G Y +L N CG + +T+ Sbjct: 1488 NSELSGKYTCKLSNECGSTETSAKLTV 1514 Score = 145 bits (352), Expect = 1e-32 Identities = 239/1123 (21%), Positives = 442/1123 (39%), Gaps = 118/1123 (10%) Query: 314 SRNIKEAAKVK-KQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQT--LEE 370 SR I E ++ KQ+ P +E+ + DI+E E+E ++ +T ++ Sbjct: 1675 SRTIAEKIDIEEKQIKHSTPEPIIEEPLSPNIQRGHSDILE----ESEFVENDETDKVQH 1730 Query: 371 LPKEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAVYSYV 430 + +ED+P+ + +++ + I+EI + + P E T V R A Sbjct: 1731 MKEEDLPK---VKSKRAKSIHIEEIEENELSSEPKTPIE---TEVPKRKASKAQAATVEE 1784 Query: 431 AETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE 490 E E +N E L S + QK + E Y +++ + L K+ + Sbjct: 1785 LEIIETLN----ETPQQLKESKFERQESQKGVRE--------YEEEQDEEMEALLKRAQK 1832 Query: 491 KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550 + + + +++ I ++ P+ + + + P P+ TW + Sbjct: 1833 QRSLVEELPQKGELDEAKPTITSSNMKDSSRPESLDICYIVKGTSNPPPKATWTINGQEL 1892 Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610 KP +M + +++ + +DAG C+ KN G A T ++ P + Sbjct: 1893 KPDSRVRMTNKGEEFKLEIVK-LKMDDAGKIECILKNPLGEARQ-TAMLEVTPEKE---- 1946 Query: 611 MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFK 670 + EG+ K Q + + + + + ++ P PD W Sbjct: 1947 ------------LRRPKLKEGL--------KDQTIQKKNTLTFKAVVIGDPVPDATWSVD 1986 Query: 671 GEEIVPD--ENISVAIESDMHMY------CS-VLKITNVKKFQEGTYTVVAVNREGEASL 721 G E+ + E + +E++ H C+ L I ++ G YT A N+ GE + Sbjct: 1987 GHELTSEAFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNS 2046 Query: 722 PIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---L 778 L + P++ P +++ V GE+ L ++ NP+ + W K+++ VK L Sbjct: 2047 SAQLTVVLR----PEIEGP-QNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENL 2101 Query: 779 PTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836 SD +T+ + + K + DEG Y + A+NS G E+S+ ++ TE+ P I Sbjct: 2102 KIVSDVANETYRL-VFKKALLSDEGYYKVVAKNSLG--ESSSEARLKAVTEK----PTII 2154 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITN 894 + V+ I ++ R P P I W N + I E I + D + + + Sbjct: 2155 TGLSDDQVEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVS 2214 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-- 952 ++ DSG YK +A+N G++ AR+T+ TF K L++S + EG+ + L+ + Sbjct: 2215 DFNDSDSGIYKAIAANVQGEADTSARITMVQTPPTFGKKLERSEDVIEGEPLELKAKING 2274 Query: 953 SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTML 1010 S + WY N + I + + D G K ++++ E++ + Sbjct: 2275 SPKPTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLC 2334 Query: 1011 VV----KETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKN-KYD 1064 V K P+F++ +D ++ + LE ++ + +V W +DG ++ N ++ Sbjct: 2335 AVAVQQKPQRPKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFE 2394 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTVVELP--PEIITRLQNQKV 1118 G + L + + G+Y + D A V + + P PE + RL Q V Sbjct: 2395 VHPDGKV-ALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTV 2453 Query: 1119 NKGNKATFEIELTKGDA-LVRWFKDGSEIQFSN-HIQLT--IDGKKQKLKIYDCDLDDAG 1174 +G FE++ A + W ++G+E+ N H++++ DG L D Sbjct: 2454 VEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGL 2513 Query: 1175 EYSC----EVGNSKCTAILTVEEPSINFTL--RLPEFIL----VPANTDAYLTVEIP--- 1221 Y E G ++ +A LTV P+ N P F+ V A+ L + P Sbjct: 2514 TYRAIAINEAGEAETSAPLTV-IPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTA 2572 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKSTT 1277 + V W K + +++ + D KK L I D Y+ L + S Sbjct: 2573 NPVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEA 2632 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 V V PP + + G D PQP W + IK+ Sbjct: 2633 NAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIK 2692 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 D L + DA +Y+ R N G ++ ++D+ Sbjct: 2693 RDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQ 2735 Score = 140 bits (340), Expect = 3e-31 Identities = 129/547 (23%), Positives = 223/547 (40%), Gaps = 34/547 (6%) Query: 663 PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722 P+ W G PDE V + D V + +V+ G YT VA G S Sbjct: 1066 PEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQ--HVRAEDVGLYTCVAQTSRGHISCS 1123 Query: 723 IVLKIK------TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK 776 L + E E P +I ++ +V G S ++ QV G P+P + W KP++ Sbjct: 1124 AELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIE 1183 Query: 777 A----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 A D +T S+ ++K + +D G Y AEN G +TV+ P Sbjct: 1184 AGGKYKFLYEDEETMSL-VIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVK-------TP 1235 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P + +++ +++ + P P + +Y++ + I E I + E + LVI Sbjct: 1236 PKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVI 1295 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQ 951 + DSG Y VA+N + S + + + K+ K EE + ++ + Sbjct: 1296 EKTMLK-DSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIE 1354 Query: 952 TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG--VIKCI-VKDQETST 1008 + KWY + EI DH I ++G D +K + + Sbjct: 1355 SEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDD 1414 Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAI-LEVEINS-ETADVVWERDGEIIKPKKNKYDFE 1066 + V + P+ + LQD V E D + L+V++ + V W D I K ++ Sbjct: 1415 IRVDVKKAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRV 1474 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNK 1123 KL I+ + G+Y+C L +E + E + V P II +L++ V +G Sbjct: 1475 DSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGAT 1534 Query: 1124 ATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQK---LKIYDCDLDDAGEYSCE 1179 E+E+ V+W ++G E+ I+++ D ++ + L + ++ GEY Sbjct: 1535 LHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVV 1594 Query: 1180 VGNSKCT 1186 V NS T Sbjct: 1595 VTNSMGT 1601 Score = 140 bits (338), Expect = 5e-31 Identities = 128/468 (27%), Positives = 208/468 (44%), Gaps = 62/468 (13%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 + VEK P GS + E QV+G+P+PQ+ W + I+ ++ Y+D+ +LVI Sbjct: 1144 LIVEKRNPVVNAGGSAM-IELQVKGFPKPQVKWTHEGKPIEAGGKYKFLYEDEETMSLVI 1202 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILE 630 ++V EDAG + C A+N G ++ L V+ P AD+L Sbjct: 1203 KDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTP---------PKLRKKIEDVDAHADLLL 1253 Query: 631 GIPPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 IP + +PK + +G +I + R+ + E +E + + IE M Sbjct: 1254 EIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEE--------------NEKVVLVIEKTM 1299 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVR 747 LK G+Y++VA N + S L + T P+++E L K IV Sbjct: 1300 ------LK-------DSGSYSIVATNELAQISEFFNLHVHT----KPKILEKLGKDKIVS 1342 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYT 804 Q E L ++ P + W K++ +K+ K DG+T+ + I D Y Sbjct: 1343 QEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKI-TGAVTTDAARYK 1401 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPS 863 +KA N G E + V+ + P Q++TV E + L +V P PS Sbjct: 1402 VKAVNIHGSVEDDIRVDVK-------KAPKITKGLQDMTVNEHDKQVTLDVKVEAFPKPS 1454 Query: 864 ITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + WY + I+ ++T D ++ ++LVI V+SE+ SG Y C SN G + A++T Sbjct: 1455 VKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSEL-SGKYTCKLSNECGSTETSAKLT 1513 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEIS 968 ++ +K L K EEG T+ LE + T + KW N +E+S Sbjct: 1514 VNCAP-RIIKQL-KDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVS 1559 Score = 137 bits (332), Expect = 3e-30 Identities = 173/727 (23%), Positives = 283/727 (38%), Gaps = 54/727 (7%) Query: 586 KNAAGFASSTTELIVE-APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 K + A+ T L+ + A LSD G V PT Sbjct: 2102 KIVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQ 2161 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V+ +I + R +P+P I WL G+ IV DE + +D + S L +++ Sbjct: 2162 VEHTKEISVMVRADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQV-TSTLTVSDFNDSD 2220 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPR 763 G Y +A N +GEA + T + PP + L +S V +GE + L A++ G+P+ Sbjct: 2221 SGIYKAIAANVQGEADTSARI---TMVQTPPTFGKKLERSEDVIEGEPLELKAKINGSPK 2277 Query: 764 PTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 PT+ W KN +P+ + + T D ++ + D G Y L +N G + + Sbjct: 2278 PTVVWYKNGEPIDDERVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVA 2337 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V++ + P F+ F+++ + T++L A+V +P P + W ++ + S I Sbjct: 2338 VQQKPQR----PKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHF 2393 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE--KVTFVKHLQKSYE 939 + +I + ++G Y+ SN G + A V I+ + K F+ L Sbjct: 2394 EVHPDGKVALIVDCAKPENAGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQ-T 2452 Query: 940 TEEGKTVILECQTSHTVSTK--WYHNKKE-ISGMDHREI--IQEGRXXXXXXXXXXXXDV 994 EG V E + + K W N E IS H +I + +G D Sbjct: 2453 VVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDG 2512 Query: 995 GVIKCIVKDQ----ETSTMLVV--------KETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 + I ++ ETS L V E P F+ L+D E +L + Sbjct: 2513 LTYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTA 2572 Query: 1043 ETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCT 1097 +V W +DG + P ++ G L I N D G YS L +ES Sbjct: 2573 NPVPMVEWSKDGVPLSP-SDRILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSE 2631 Query: 1098 AEVTV--VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQL 1154 A V V +PP + + G A F ++ V W KDG I+ S+ + Sbjct: 2632 ANAAVHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHI 2691 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAIL-TVEEPSINFTLRLPEFILVP 1209 DG L + +C DDA Y G CTA L V++ + P F+ Sbjct: 2692 KRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRI 2751 Query: 1210 ANTDAY--LTVEIPD-----ETLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIRKCTED 1261 +T+ + +T + +V WY + + + + +D LII E Sbjct: 2752 GDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLDEA 2811 Query: 1262 DQCEYTC 1268 D +Y+C Sbjct: 2812 DLGKYSC 2818 Score = 134 bits (324), Expect = 3e-29 Identities = 159/701 (22%), Positives = 293/701 (41%), Gaps = 79/701 (11%) Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK-----KNKYDFEKRGHIRK 1073 FI+ ++ +++ + EV + S+ W +D + + + + + ++ K Sbjct: 844 FIKTIRGADIEPGEKFTFEVALKSKPDTFTWLKDDKPLDSNAIMLGRIQMRHSEDSYLYK 903 Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE------------IITRLQNQK 1117 LYI T D G Y+ + +C+A + V ++ PE + +L++ + Sbjct: 904 LYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKDTE 963 Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ---KLKIYDCDLDD 1172 + + F +++ +GD V +FKDG ++ S+ ++ + + +L I + + D Sbjct: 964 LAENTYLRFMVKV-RGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMSD 1022 Query: 1173 AGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228 AGEY C N C A L V ++ + PE ++P P ET + Sbjct: 1023 AGEYKCVASNKWGEDSCEATLKVTTEDLHKDM--PEGEILP-----------PGETPEFQ 1069 Query: 1229 WYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKS----TTKLKV- 1281 W K + E E+F ++ D L+ + +D YTCV ++ + +L V Sbjct: 1070 WKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVH 1129 Query: 1282 ----EVVEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHT 1334 ++V P P ++ +R + G + + + FP+P +W K I+ K+ Sbjct: 1130 GTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGKPIEAGGKYK 1189 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 D ++ SL IK V+ DAG Y EN G EM +T+ K P + I ++D+ Sbjct: 1190 FLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTV--KTPPKLRKKIEDVDA 1247 Query: 1395 SSINICWDEP---ENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYR 1450 + ++ + P E T +++Y + +EI E I V+ K I+ S Sbjct: 1248 HA-DLLLEIPVEIEGTPRPKVVFY-KDGKEIKKDERIKVVEENEKVVLVIEKTMLKDSGS 1305 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 + A NE+ ++ +E++ + TK +EK K+ E EL P+ Sbjct: 1306 YSIVATNEL-----AQISEFFNLHVHTK--PKILEKLGKDKIVSQEEKFELRVKIESEPE 1358 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXX----XXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 +V WY+D ++K++ + YK A N HG VE V Sbjct: 1359 AEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVD 1418 Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKE 1625 +++ P IT +D+ ++ + + +E P P V WY + ++ E E+ + Sbjct: 1419 VKKAPKITKGLQDM-TVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSD 1477 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + IKE+ S KYT + SN G++ L V P Sbjct: 1478 DGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAP 1518 Score = 130 bits (315), Expect = 3e-28 Identities = 170/793 (21%), Positives = 327/793 (41%), Gaps = 77/793 (9%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YC 692 F K + ++ G E L + P+ WL K ++ + I + H Y Sbjct: 844 FIKTIRGADIEPGEKFTFEVALKSKPDT-FTWL-KDDKPLDSNAIMLGRIQMRHSEDSYL 901 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVL---------KIKTGEKEPPQVIEPLKS 743 L I G YT +A G A+ +L +++ + + P+ + LK Sbjct: 902 YKLYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKD 961 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSITILKPK-KVK 798 + + + +V G+P P + + K+ V+ + D +L P+ ++ Sbjct: 962 TELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMS 1021 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEE-NAEPPLFINRFQEITVKEKGTIKLVARVT 857 D G Y A N G E S T++ TE+ + + P +G I + Sbjct: 1022 DAGEYKCVASNKWG--EDSCEATLKVTTEDLHKDMP-------------EGEI-----LP 1061 Query: 858 RNPVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 P W ++ P E + D +++ LV +V +E D G Y CVA S G Sbjct: 1062 PGETPEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAE-DVGLYTCVAQTSRGHI 1120 Query: 916 SHGARVTI---------DVEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKWYHNKK 965 S A +T+ + EK + + G +I L+ + KW H K Sbjct: 1121 SCSAELTVHGTVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWTHEGK 1180 Query: 966 EI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIR 1021 I +G ++ + ++ D G C +++ +T+ M + +T P+ + Sbjct: 1181 PIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPPKLRK 1240 Query: 1022 KLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 K++D + + + VEI + VV+ +DG+ IK + E+ + L I T Sbjct: 1241 KIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKV-VLVIEKTM 1299 Query: 1081 VHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQK-VNKGNKATFEIEL-TKGDA 1135 + D G YS + +E V P+I+ +L K V++ K +++ ++ +A Sbjct: 1300 LKDSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRVKIESEPEA 1359 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA---ILTVE 1192 V+W+KD +EI+ S+H + DG+ LKI DA Y + N + I Sbjct: 1360 EVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDDIRVDV 1419 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTE-KFTLISDV 1248 + + T L + + D +T+++ E V WY + I +T+ +FT + Sbjct: 1420 KKAPKITKGLQDMTV--NEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSD 1477 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTL 1307 L+I++ + +YTC L + +T+ ++ V P+I+ ++ ++ G+ + L Sbjct: 1478 DGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHL 1537 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS---KSASLTIKKVENTDAGIYKLRLEN 1364 V+ + P P +W+ N + + K S D+ ++ +L + ++ + G Y++ + N Sbjct: 1538 EVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTN 1597 Query: 1365 NCGHADVEMNVTI 1377 + G + VT+ Sbjct: 1598 SMGTVSSKSYVTV 1610 Score = 130 bits (313), Expect = 5e-28 Identities = 134/572 (23%), Positives = 237/572 (41%), Gaps = 49/572 (8%) Query: 539 PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 P+ W + A +P + F++ DD++ LV + V ED G +TCVA+ + G S + E Sbjct: 1066 PEFQWKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAE 1125 Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L V HG+ + + E P + + V+ G ++E ++ Sbjct: 1126 LTV------HGTVNQL--------------VREPEKPVLIVEKRNPVVNAGGSAMIELQV 1165 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P+P + W +G+ I E + M L I +V+K G Y A N G Sbjct: 1166 KGFPKPQVKWTHEGKPIEAGGKYKFLYEDEETM---SLVIKDVQKEDAGKYLCTAENEIG 1222 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 + + L +KT PP++ + ++ + + + ++ G PRP + + K+ K +K Sbjct: 1223 SDTAEMTLTVKT----PPKLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKK 1278 Query: 778 LPTKS--DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + + + +++ +KD G Y++ A N +A+ S + T +P + Sbjct: 1279 DERIKVVEENEKVVLVIEKTMLKDSGSYSIVATNE--LAQISEFFNLHVHT----KPKIL 1332 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 ++ V ++ +L ++ P + WY+++ I S+ DGE L IT Sbjct: 1333 EKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGA 1392 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVILECQTS- 953 + D+ YK A N G RV DV+K K LQ E K V L+ + Sbjct: 1393 VT-TDAARYKVKAVNIHGSVEDDIRV--DVKKAPKITKGLQDMTVNEHDKQVTLDVKVEA 1449 Query: 954 -HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQETSTMLV 1011 S KWY ++ EI+ + ++ G C + ++ ST Sbjct: 1450 FPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETS 1509 Query: 1012 VKETI---PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNKYDFE 1066 K T+ P I++L+D V+E LEVE+ T V W R+G E+ + K + Sbjct: 1510 AKLTVNCAPRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRD 1569 Query: 1067 KRGH-IRKLYIRNTSVHDEGEYSCILRDESCT 1097 + H L + +EGEY ++ + T Sbjct: 1570 TQRHETFNLAVNLIKYEEEGEYEVVVTNSMGT 1601 Score = 128 bits (309), Expect = 2e-27 Identities = 151/614 (24%), Positives = 252/614 (41%), Gaps = 67/614 (10%) Query: 510 PIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P F +KL R + +G ++ + ++ G P+P + W++ I DD+ V T Sbjct: 2248 PTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPI----------DDERVKTS 2297 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 V+ + GT ++A S +L+++ P + V Sbjct: 2298 VLPD------GTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQR------- 2344 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 P F K K + G + LE ++ A P P++ W+ G + NI + D Sbjct: 2345 -----PKFLKCFKDVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDG 2399 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIV 746 + L + K G Y + N+ G+A ++I EK+P P+ + L V Sbjct: 2400 KV---ALIVDCAKPENAGKYELQVSNKYGDAMGEASVEI---EKKPTKPEFLVRLVPQTV 2453 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802 +G V + VG+P P +TW +N V K + D S+ +L +G+ Sbjct: 2454 VEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGL 2513 Query: 803 -YTLKAENSEGIAETSAVITVEEPT--EENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 Y A N G AETSA +TV T E E P+F++ +++T E ++ L A T N Sbjct: 2514 TYRAIAINEAGEAETSAPLTVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTAN 2573 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 PVP + W ++ +SPS+ I DG+ + L I N D+G Y SN G+ S A Sbjct: 2574 PVPMVEWSKDGVPLSPSDRILVTCDGKKVGLEILNAVPS-DAGRYSVKISNPLGEESSEA 2632 Query: 920 RVTIDVEKVTFVKHLQKSY---ETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHRE 974 V KV H +++ + G+ C+ S + W + I D Sbjct: 2633 NAA--VHKVFMPPHFTQTFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYH 2690 Query: 975 IIQEGRXXXXXXXXXXXXDVGV--IKCIVKDQE---TSTMLVV-----KETI--PEFIRK 1022 I ++G D V + I K+ E T+++ VV K+ I P F+++ Sbjct: 2691 IKRDGDLCCLYVLNCSPDDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKR 2750 Query: 1023 LQDFEV-KEKDVAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 + D E+ K +V W D ++ + K + + G +R L I + Sbjct: 2751 IGDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLR-LIISDLD 2809 Query: 1081 VHDEGEYSCILRDE 1094 D G+YSC + +E Sbjct: 2810 EADLGKYSCKITNE 2823 Score = 127 bits (307), Expect = 3e-27 Identities = 221/1082 (20%), Positives = 399/1082 (36%), Gaps = 103/1082 (9%) Query: 761 NPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 NP P TW N KP + + G+ + I+K K+ D G +N G A + Sbjct: 1878 NPPPKATWTINGQELKPDSRVRMTNKGEEFKLEIVK-LKMDDAGKIECILKNPLGEARQT 1936 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISPS 876 A++ V P +E P L ++ T+++K T+ A V +PVP TW +E+ S + Sbjct: 1937 AMLEVT-PEKELRRPKLK-EGLKDQTIQKKNTLTFKAVVIGDPVPDATWSVDGHELTSEA 1994 Query: 877 ----ETITQNFDGE--------NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + I + D E L I + ++G Y A N G+ + A++T+ Sbjct: 1995 FEKYKIILETEDHEIQDGLKECTYTLTIPRCE-RCNAGKYTFFAKNKWGECNSSAQLTV- 2052 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE--GRXX 982 V + S E ++ + Q + W + + + ++ +I+ + Sbjct: 2053 VLRPEIEGPQNVSVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETY 2112 Query: 983 XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI--PEFIRKLQDFEVKE-KDVAILE 1037 D G K + K+ E+S+ +K P I L D +V+ K+++++ Sbjct: 2113 RLVFKKALLSDEGYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQVEHTKEISVMV 2172 Query: 1038 VEINSETADVVWERDGE-IIKPKKNKYDFEKRGHIRK-LYIRNTSVHDEGEYSCI---LR 1092 + W +G+ I++ +K+K + + L + + + D G Y I ++ Sbjct: 2173 RADGLPKPQIRWLLNGKPIVEDEKHKIESHADAQVTSTLTVSDFNDSDSGIYKAIAANVQ 2232 Query: 1093 DESCT-AEVTVVELPPEIITRLQ-NQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFS 1149 E+ T A +T+V+ PP +L+ ++ V +G + ++ V W+K+G I Sbjct: 2233 GEADTSARITMVQTPPTFGKKLERSEDVIEGEPLELKAKINGSPKPTVVWYKNGEPIDDE 2292 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPE 1204 + KL I D+G Y + G S C + V++ P L+ + Sbjct: 2293 RVKTSVLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFK 2352 Query: 1205 FILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + +P L ++ +V W K + + + +I C + + Sbjct: 2353 DVKLPIGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALIVDCAKPEN 2412 Query: 1264 C-EYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 +Y + DA +++E P+ + + G V V P P Sbjct: 2413 AGKYELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPK 2472 Query: 1319 DEWIVN-SKIIKKCKHTKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNV 1375 W N +++I KH K S S+ + N D Y+ N G A+ + Sbjct: 2473 LTWSRNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAGEAETSAPL 2532 Query: 1376 TIL---DKPSPPGKPNILE-----IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 T++ + SP KP L ++ P ++ + + + ++ Sbjct: 2533 TVIPATNSESPEEKPMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDR 2592 Query: 1428 ISVK-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 I V + K I N + + R+ N + + +KV P + Sbjct: 2593 ILVTCDGKKVGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVF-----MPPHFTQ 2647 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX----XXXXXXXX 1542 ++ P D + C GVPQP+V W +DG +K + + R Sbjct: 2648 TFTDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSP 2707 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-------VTAV 1595 Y+ A N GE + + + + E ++GD L TA Sbjct: 2708 DDAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTAC 2767 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEASNTAGT 1653 G P PEV WY N KL + T + ++R I +L + KY+ + +N G Sbjct: 2768 ASGYPEPEVEWYHNDQKLFPSNRIKMET-DPNGLLRLIISDLDEADLGKYSCKITNEYGG 2826 Query: 1654 SSVEVTLKV------------------YDKPSKPEGPV------IMREISRESVTIEWKP 1689 L + +DK + PV I+ +++ T+ WKP Sbjct: 2827 DICHANLNMDEGLETRAKRPITDQYTEFDKYKRTGAPVPLSDPPIISQMTDRHCTLSWKP 2886 Query: 1690 PLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 + G Y +E E N W V R T ++ L +Y FRV +N G Sbjct: 2887 SIPPGPRAPVTYQLEMCELPNGDWFTVRTGIRSC-TCGVRNLEPFRDYKFRVRVENKYGI 2945 Query: 1750 SE 1751 S+ Sbjct: 2946 SD 2947 Score = 123 bits (297), Expect = 5e-26 Identities = 141/668 (21%), Positives = 282/668 (42%), Gaps = 48/668 (7%) Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194 W +G E++ + +++T G++ KL+I +DDAG+ C +G ++ TA+L V Sbjct: 1885 WTINGQELKPDSRVRMTNKGEEFKLEIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPE 1944 Query: 1195 SINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTW-----------YKKKSVIEDT 1239 +L E + + NT + V I D D TW ++K +I +T Sbjct: 1945 KELRRPKLKEGLKDQTIQKKNTLTFKAVVIGDPVPDATWSVDGHELTSEAFEKYKIILET 2004 Query: 1240 EKFTLISDVKK--RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297 E + +K+ TL I +C + +YT + ++ ++ + Sbjct: 2005 EDHEIQDGLKECTYTLTIPRCERCNAGKYTFFAKNKWGECNSSAQLTVVLRPEIEGPQNV 2064 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTK--PSIDSKSASLTIKKVENTDA 1355 + G L+ QA PQ W + +++K+ ++ K + +++ L KK +D Sbjct: 2065 SVIPGEATELVCKIQANPQAEVHWTKDDQVVKETENLKIVSDVANETYRLVFKKALLSDE 2124 Query: 1356 GIYKLRLENNCGHADVEMNV-TILDKPS---PPGKPNILEIDSSSINICWDE-PENTGNS 1410 G YK+ +N+ G + E + + +KP+ + S+ + D P+ Sbjct: 2125 GYYKVVAKNSLGESSSEARLKAVTEKPTIITGLSDDQVEHTKEISVMVRADGLPKPQIRW 2184 Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 + + E E + +T T T + + + S ++A A N + ++T+ Sbjct: 2185 LLNGKPIVEDEKHKIESHADAQVTSTLT-VSDFNDSDSGIYKAIAAN---VQGEADTSAR 2240 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY- 1529 +++ +E+ I EP +EL G P+P V WY++G+ + + Sbjct: 2241 ITMVQTPPTFGKKLERSEDVIEGEP---LELKAKINGSPKPTVVWYKNGEPIDDERVKTS 2297 Query: 1530 ---ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHK 1585 + YK + N +GE C V +QQKP + K K Sbjct: 2298 VLPDGTVKLNIEHARPSDSGAYKLVIQNPNGESACLCAVAVQQKPQRPKFLKCFKDVKLP 2357 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGN--KLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 +G+ + A ++ PPPEV W K+G ++ ++ + + K ++I + K ++ KY Sbjct: 2358 IGETLRLEAQVQAHPPPEVKWIKDGVPVRVSSNIHFEVHPDGKVALI-VDCAKPENAGKY 2416 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK-PPLDDGGLELTKY 1701 ++ SN G + E ++++ KP+KPE V ++ + E ++++ + +LT Sbjct: 2417 ELQVSNKYGDAMGEASVEIEKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWS 2476 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM-FRVIAQNPVGFSEALESEPIVI 1760 +N+ +K++++ + N+ + + +R IA N G EA S P+ + Sbjct: 2477 RNGAEVISDNKHVKISELPDGTSVLLLDAANQARDGLTYRAIAINEAG--EAETSAPLTV 2534 Query: 1761 KTALDVPS 1768 A + S Sbjct: 2535 IPATNSES 2542 Score = 121 bits (291), Expect = 3e-25 Identities = 107/429 (24%), Positives = 172/429 (40%), Gaps = 36/429 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDD 562 E++ P F+ +L P+ +G V+FE + G+P P++TW R A +I ++ ++ Sbjct: 2436 EKKPTKPEFLVRLVPQTVVEGFPVKFEVKAVGHPAPKLTWSRNGAEVISDNKHVKISELP 2495 Query: 563 DNVATLVIREVFP-EDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 D + L++ D T+ +A N AG A ++ L V + E Sbjct: 2496 DGTSVLLLDAANQARDGLTYRAIAINEAGEAETSAPLTVIPATNSESPEEK--------- 2546 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 P F K DEG ++L A P P + W G + P + I Sbjct: 2547 ------------PMFLHPLKDVTADEGKSLVLSAPFTANPVPMVEWSKDGVPLSPSDRIL 2594 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 V + L+I N G Y+V N GE S + PP + Sbjct: 2595 VTCDGKK----VGLEILNAVPSDAGRYSVKISNPLGEESSEANAAVHKVFM-PPHFTQTF 2649 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVK 798 + G +V G P+P + W K+ P+K K DGD + +L Sbjct: 2650 TDLQQLPGRDAKFPCRVSGVPQPEVVWTKDGLPIKESDKYHIKRDGDLCCLYVLNCSP-D 2708 Query: 799 DEGVYTLKAENSEG--IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 D VY +A N EG + S + + ++ EPP F+ R + + + T K A Sbjct: 2709 DAAVYRARAINKEGEEVCTASLEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTACA 2768 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKS 915 + P P + WY N++ + PS I D + L+I+++D E D G Y C +N G Sbjct: 2769 SGYPEPEVEWYHNDQKLFPSNRIKMETDPNGLLRLIISDLD-EADLGKYSCKITNEYGGD 2827 Query: 916 SHGARVTID 924 A + +D Sbjct: 2828 ICHANLNMD 2836 Score = 113 bits (273), Expect = 4e-23 Identities = 153/689 (22%), Positives = 282/689 (40%), Gaps = 72/689 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 PEF+ KL+D E+ E V++ + DV++ +DG I++ K ++Y+ + R Y Sbjct: 953 PEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVE-KSDRYEVIREHSDRGFY 1011 Query: 1076 ---IRNTSVHDEGEYSCILR----DESC--TAEVTVVELPPEIITRLQNQKVNKGNKATF 1126 I + D GEY C+ ++SC T +VT +L ++ + + + G F Sbjct: 1012 ELLIPEVQMSDAGEYKCVASNKWGEDSCEATLKVTTEDLHKDMP---EGEILPPGETPEF 1068 Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY--DCDLDDAGEYSCEV---- 1180 + W KDG+ + ++ + + L + +D G Y+C Sbjct: 1069 Q-----------WKKDGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSR 1117 Query: 1181 GNSKCTAILTVEEPSINFTLRLPE---FIL------VPANTDAYLTVEIPD-ETLDVTWY 1230 G+ C+A LTV ++N +R PE I+ V A A + +++ V W Sbjct: 1118 GHISCSAELTVHG-TVNQLVREPEKPVLIVEKRNPVVNAGGSAMIELQVKGFPKPQVKWT 1176 Query: 1231 KKKSVIEDTEKFT-LISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVEFPP 1288 + IE K+ L D + +L+I+ ++D +Y C + S T V+ PP Sbjct: 1177 HEGKPIEAGGKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIGSDTAEMTLTVKTPP 1236 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 K+ + + + V+ + P+P + + K IKK + K +++ L I+ Sbjct: 1237 KLRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVIE 1296 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEIDSS-SINICWDEP 1404 K D+G Y + N N+ + KP GK I+ + + + + Sbjct: 1297 KTMLKDSGSYSIVATNELAQISEFFNLHVHTKPKILEKLGKDKIVSQEEKFELRV---KI 1353 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISD 1463 E+ + + +Y + EI +++ +K +T I T + R++ AVN + Sbjct: 1354 ESEPEAEVKWYKDD-AEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVE 1412 Query: 1464 ASETTEYYKVIKETK-IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + K K TK +Q TV + K +T D+++ P+P V WY D ++ Sbjct: 1413 DDIRVDVKKAPKITKGLQDMTVNEHDKQVTL----DVKVEAF----PKPSVKWYLDEMEI 1464 Query: 1523 KTAKATY-----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577 K + ++ Y C N+ G ETS + + P I Sbjct: 1465 TETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQL 1524 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKTSVIRIKE 1634 +D + G + +EG P P V W +NG ++ D I T + +T + + Sbjct: 1525 KDTTVEE--GATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNL 1582 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 +K +Y + +N+ GT S + + V+ Sbjct: 1583 IKYEEEGEYEVVVTNSMGTVSSKSYVTVH 1611 Score = 97.1 bits (231), Expect = 5e-18 Identities = 85/313 (27%), Positives = 136/313 (43%), Gaps = 23/313 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P K K + V + L ++ + PE ++ W EI ++ I+ D Y Sbjct: 1329 PKILEKLGKDKIVSQEEKFELRVKIESEPEAEVKWYKDDAEIKSSDH--YVIKKDGETY- 1385 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GES 751 +LKIT Y V AVN G + I+ K+ P++ + L+ M V + + Sbjct: 1386 -ILKITGAVTTDAARYKVKAVNIHGS----VEDDIRVDVKKAPKITKGLQDMTVNEHDKQ 1440 Query: 752 VILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 V L +V P+P++ W + + K T+ D D ++K + G YT K Sbjct: 1441 VTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVKLVIKEVNSELSGKYTCKLS 1500 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G ETSA +TV N P + I + ++ TV+E T+ L V P P++ W R Sbjct: 1501 NECGSTETSAKLTV------NCAPRI-IKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLR 1553 Query: 869 NNEIISPSETITQNFDGENIEL--VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 N +S I + D + E + N+ + G+Y+ V +NS G S + VT V Sbjct: 1554 NGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVT--VH 1611 Query: 927 KVTFVKHLQKSYE 939 KVT ++ E Sbjct: 1612 KVTHTDAIEVEEE 1624 Score = 84.2 bits (199), Expect = 4e-14 Identities = 131/614 (21%), Positives = 249/614 (40%), Gaps = 82/614 (13%) Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQL-------TIDGKKQK 1162 I ++ + G K TFE+ L W KD + SN I L + D K Sbjct: 845 IKTIRGADIEPGEKFTFEVALKSKPDTFTWLKDDKPLD-SNAIMLGRIQMRHSEDSYLYK 903 Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRL-----PEFILVPANTD 1213 L I DD+G Y+ G + C+A+L V + + L PEF++ +T+ Sbjct: 904 LYINPTHDDDSGYYTALATTPHGTAACSALLIVHQMTPEERLERAKTDKPEFVVKLKDTE 963 Query: 1214 ----AYLTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKR---TLIIRKCTEDDQ 1263 YL + D DV ++K ++E ++++ +I + R L+I + D Sbjct: 964 LAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYELLIPEVQMSDA 1023 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 EY CV ++ K + E K+ + + G +L + P +W Sbjct: 1024 GEYKCV-----ASNKWGEDSCEATLKVTTEDLHKDMPEGE---ILPPGET---PEFQWKK 1072 Query: 1324 NSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGH----ADVEMNVTI 1377 + + + K + D S +L + V D G+Y + + GH A++ ++ T+ Sbjct: 1073 DGAPFEPDERFKVLMGDDEDSLALVFQHVRAEDVGLYTCVAQTSRGHISCSAELTVHGTV 1132 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI--------- 1428 P KP +L ++ + + N G S +I V+ +W Sbjct: 1133 NQLVREPEKP-VLIVEKRNPVV------NAGGSAMIELQVKGFPKPQVKWTHEGKPIEAG 1185 Query: 1429 -SVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 K + + + + I++++ + ++ A NE+ SD +E T K P Sbjct: 1186 GKYKFLYEDEETMSLVIKDVQKEDAGKYLCTAENEIG-SDTAEMTLTVKT-------PPK 1237 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYEN-RXXXXXXX 1539 + K ++++ + +E+ G P+PKV +Y+DGK++K K EN + Sbjct: 1238 LRKKIEDVDAHADLLLEIPVEIEGTPRPKVVFYKDGKEIKKDERIKVVEENEKVVLVIEK 1297 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVTAVIE 1597 Y +A N+ ++ + + KP I E + + V E + + IE Sbjct: 1298 TMLKDSGSYSIVATNELAQISEFFNLHVHTKPKIL---EKLGKDKIVSQEEKFELRVKIE 1354 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 P EV WYK+ ++++ Y I +T +++I + +++Y ++A N G+ + Sbjct: 1355 SEPEAEVKWYKDDAEIKSSDHYVIKKDGETYILKITGAVTTDAARYKVKAVNIHGSVEDD 1414 Query: 1658 VTLKVYDKPSKPEG 1671 + + V P +G Sbjct: 1415 IRVDVKKAPKITKG 1428 Score = 69.3 bits (162), Expect = 1e-09 Identities = 55/212 (25%), Positives = 89/212 (41%), Gaps = 18/212 (8%) Query: 634 PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +K + V+E + L+ ++ A P+P + W EI + ++SD + Sbjct: 1423 PKITKGLQDMTVNEHDKQVTLDVKVEAFPKPSVKWYLDEMEITETKTEFTRVDSDDGVK- 1481 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I V G YT N G L + P++I+ LK V +G ++ Sbjct: 1482 --LVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCA----PRIIKQLKDTTVEEGATL 1535 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK--DEGVYTLKA 807 L +V G P PT+ W +N + V A + D H L +K +EG Y + Sbjct: 1536 HLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFNLAVNLIKYEEEGEYEVVV 1595 Query: 808 ENSEGIAETSAVITVEEPTEENA-----EPPL 834 NS G + + +TV + T +A EPP+ Sbjct: 1596 TNSMGTVSSKSYVTVHKVTHTDAIEVEEEPPM 1627 Score = 62.1 bits (144), Expect = 2e-07 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 2/142 (1%) Query: 1324 NSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 N I+ + K D S L + D G+YK+ N G + P Sbjct: 3571 NDSIVAESHRVKIDTDEFGRSHLKFSPALSFDQGMYKVVARNKIGQTVARARIVFGSTPE 3630 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQ 1441 P P + + I + W +P GNS ++ Y +EY+ D EW NI ++ Sbjct: 3631 EPDSPESDQSSDTEIFLTWKQPRFDGNSPVLCYSLEYKLADDIEWTKKADNIDHEFYLMR 3690 Query: 1442 NLKTNSSYRFRAYAVNEVDISD 1463 L +SSY FR A N + SD Sbjct: 3691 GLTPSSSYMFRLAARNAIGWSD 3712 Score = 60.9 bits (141), Expect = 4e-07 Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 10/167 (5%) Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P+P +++ F E I ++ + + L I + + G Y VA N GEA Sbjct: 3030 PKPKVSFYFNDELIESGGRFDMSYTRNGQ---ATLFINKMLERDVGWYEAVATNEHGEAR 3086 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--- 777 + L+I E PQ I + V A++VG P P I W K+ KP+ A Sbjct: 3087 QRVRLEIA----EMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTR 3142 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 + S ++ ++ KDEG+Y++ A N G +SA++ VEE Sbjct: 3143 IKVSSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHVEE 3189 Score = 57.2 bits (132), Expect = 5e-06 Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 2/109 (1%) Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y + A N G + + P +P+ P + E + + WK P DG + Y+ Sbjct: 3606 YKVVARNKIGQTVARARIVFGSTPEEPDSPESDQSSDTE-IFLTWKQPRFDGNSPVLCYS 3664 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 +E D+ W K AD + D E Y ++ L + YMFR+ A+N +G+S+ Sbjct: 3665 LEYKLADDIEWTKKAD-NIDHEFYLMRGLTPSSSYMFRLAARNAIGWSD 3712 Score = 54.4 bits (125), Expect = 3e-05 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 9/114 (7%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 +++ ARN+IG ++ +I G T P P + +S+ + L W +P +G SP Sbjct: 3606 YKVVARNKIGQTVARA---RIVFGSTPEEPDSPES---DQSSDTEIFLTWKQPRFDGNSP 3659 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHE-HCIENIKEKDEIIFRISAENTVGVS 1949 + Y +E+K WTK HE + + + +FR++A N +G S Sbjct: 3660 VLCYSLEYKLADDIEWTK--KADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711 Score = 52.0 bits (119), Expect = 2e-04 Identities = 31/124 (25%), Positives = 53/124 (42%), Gaps = 1/124 (0%) Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 +L+++ S+ + T A + P K+ K V+EG+ + LE Sbjct: 1481 KLVIKEVNSELSGKYTCKLSNECGSTETSAKLTVNCAPRIIKQLKDTTVEEGATLHLEVE 1540 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + P P + WL G E+ D I ++ ++ H + L + +K +EG Y VV N Sbjct: 1541 VEGCPTPTVKWLRNGREVSADARIKISRDTQRHETFN-LAVNLIKYEEEGEYEVVVTNSM 1599 Query: 717 GEAS 720 G S Sbjct: 1600 GTVS 1603 Score = 50.8 bits (116), Expect = 4e-04 Identities = 23/96 (23%), Positives = 46/96 (47%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 L V ++ ++++ P F++++ G T +F GYP P++ W+ + PS Sbjct: 2730 LEVVDQIQAKKKIEPPTFLKRIGDTELFKGMTAKFTACASGYPEPEVEWYHNDQKLFPSN 2789 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +M D + + L+I ++ D G ++C N G Sbjct: 2790 RIKMETDPNGLLRLIISDLDEADLGKYSCKITNEYG 2825 Score = 50.0 bits (114), Expect = 7e-04 Identities = 25/92 (27%), Positives = 47/92 (51%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+ + ++ V+F+ ++ G P P+I W++ + S ++ + A LV Sbjct: 3097 PQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTRIKVSSFFPDTAVLV 3156 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I ++ +D G ++ A+N AG SS+ L VE Sbjct: 3157 INDIITKDEGLYSVSARNVAGSISSSAMLHVE 3188 Score = 49.6 bits (113), Expect = 0.001 Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVAT 567 P FV KL+ + + ++F +V G P P + +F+ I++ S +++ + D Sbjct: 953 PEFVVKLKDTELAENTYLRFMVKVRGDPNPDVIFFKDGVIVEKSDRYEVIREHSDRGFYE 1012 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L+I EV DAG + CVA N G S L V Sbjct: 1013 LLIPEVQMSDAGEYKCVASNKWGEDSCEATLKV 1045 Score = 49.2 bits (112), Expect = 0.001 Identities = 39/162 (24%), Positives = 69/162 (42%), Gaps = 8/162 (4%) Query: 1507 GVPQPKVTWYRDGKKLKTA-----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P+PKV++Y + + +++ T + Y+ +A N+HGE Sbjct: 3028 GYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQ 3087 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + I + P I +I+ G + A I G+P PE+ WYK+ L + Sbjct: 3088 RVRLEIAEMPQF-IRRPEIQYAMHRG-KVRFDARIVGVPYPEIKWYKDWKPLAASTRIKV 3145 Query: 1622 TT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ T+V+ I ++ Y++ A N AG+ S L V Sbjct: 3146 SSFFPDTAVLVINDIITKDEGLYSVSARNVAGSISSSAMLHV 3187 Score = 48.4 bits (110), Expect = 0.002 Identities = 44/171 (25%), Positives = 78/171 (45%), Gaps = 12/171 (7%) Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHS--ITILKPKKV-KDEGVYTLKAENSEGIA 814 V G P+P +++ N++ +++ T + T+ K + +D G Y A N G A Sbjct: 3026 VYGYPKPKVSFYFNDELIESGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEA 3085 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 + + AE P FI R + +G ++ AR+ P P I WY++ + ++ Sbjct: 3086 RQRVRLEI-------AEMPQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLA 3138 Query: 875 PSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 S I +F + LVI ++ ++ D G Y A N AG S A + ++ Sbjct: 3139 ASTRIKVSSFFPDTAVLVINDIITK-DEGLYSVSARNVAGSISSSAMLHVE 3188 Score = 47.6 bits (108), Expect = 0.004 Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Query: 499 EKPTSEEQSMAPIFVEKLRPKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 E+P + + AP F+ + D +T F V GYP+P+++++ +I+ F Sbjct: 2991 ERPPHDNMAQAPRFLRQEHDTQYGVKDQNTNLFWF-VYGYPKPKVSFYFNDELIESGGRF 3049 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 M Y + ATL I ++ D G + VA N G A L I E P Sbjct: 3050 DMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQRVRLEIAEMP 3097 Score = 46.0 bits (104), Expect = 0.011 Identities = 67/294 (22%), Positives = 122/294 (41%), Gaps = 27/294 (9%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGV--PQPKVTWYRDGKKLK-TAKATYENR---XXX 1535 PT+ ++ P E +++ I G P PK TW +G++LK ++ N+ Sbjct: 1851 PTITSSNMKDSSRP-ESLDICYIVKGTSNPPPKATWTINGQELKPDSRVRMTNKGEEFKL 1909 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS--NEDIK-QKHKVGDEWLV 1592 +CI N GE + ++ + + + E +K Q + + Sbjct: 1910 EIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPEKELRRPKLKEGLKDQTIQKKNTLTF 1969 Query: 1593 TAVIEGIPPPEVIWYKNGNKLEND--KEYNIT-----------TKEKTSVIRIKELKRSH 1639 AV+ G P P+ W +G++L ++ ++Y I KE T + I +R + Sbjct: 1970 KAVVIGDPVPDATWSVDGHELTSEAFEKYKIILETEDHEIQDGLKECTYTLTIPRCERCN 2029 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD-DGGLEL 1698 + KYT A N G + L V +P + EGP + I E+ + K + + Sbjct: 2030 AGKYTFFAKNKWGECNSSAQLTVVLRP-EIEGPQNVSVIPGEATELVCKIQANPQAEVHW 2088 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 TK E +N + V+DV + +K + E ++V+A+N +G S + Sbjct: 2089 TKDDQVVKETENLK--IVSDVANETYRLVFKKALLSDEGYYKVVAKNSLGESSS 2140 Score = 46.0 bits (104), Expect = 0.011 Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 7/118 (5%) Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 D+ ++++ A N +G ++ R+ +T P P +P + + I +T W P +D Sbjct: 3602 DQGMYKVVARNKIGQTVAR----ARIVFGST-PEEPDSPESDQSSDTEIFLT-WKQPRFD 3655 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 G +P+L Y++ + W + +++ + +R L+ + +YM R+ ARN IG S+ Sbjct: 3656 GNSPVLCYSLEYKLADDIEWTKKAD-NIDHEFYLMRGLTPSSSYMFRLAARNAIGWSD 3712 Score = 44.0 bits (99), Expect = 0.046 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 3/95 (3%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F ++P+ QY + + R+V +P P+I W + + I V S + Sbjct: 3097 PQFIRRPEIQYAMHRGKVRFDARIVGVPYPEIKWYKDWKPLAASTRIKV---SSFFPDTA 3153 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 VL I ++ EG Y+V A N G S +L ++ Sbjct: 3154 VLVINDIITKDEGLYSVSARNVAGSISSSAMLHVE 3188 Score = 43.6 bits (98), Expect = 0.061 Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT- 567 AP +++L+ +G+T+ E +VEG P P + W R + ++ D T Sbjct: 1517 APRIIKQLKDTTVEEGATLHLEVEVEGCPTPTVKWLRNGREVSADARIKISRDTQRHETF 1576 Query: 568 -LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + + E+ G + V N+ G SS + + V Sbjct: 1577 NLAVNLIKYEEEGEYEVVVTNSMGTVSSKSYVTV 1610 Score = 42.7 bits (96), Expect = 0.11 Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 13/181 (7%) Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGI--PPPEVIWYKNGNKLENDKEYNITTKE 1625 + KP IT SN + + D + +++G PPP+ W NG +L+ D +T K Sbjct: 1848 EAKPTITSSNMKDSSRPESLD---ICYIVKGTSNPPPKATWTINGQELKPDSRVRMTNKG 1904 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVT-LKVYDKPSKPEGPVIMREISR 1680 + + I +LK + K N G T+ +EVT K +P EG + + + Sbjct: 1905 EEFKLEIVKLKMDDAGKIECILKNPLGEARQTAMLEVTPEKELRRPKLKEG--LKDQTIQ 1962 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 + T+ +K + + ++++ HE + + K + + E + IQ + C Y Sbjct: 1963 KKNTLTFKAVVIGDPVPDATWSVDGHELTSEAFEKY-KIILETEDHEIQDGLKECTYTLT 2021 Query: 1741 V 1741 + Sbjct: 2022 I 2022 Score = 41.9 bits (94), Expect = 0.19 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 8/113 (7%) Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 M++V+A+N +G + + IV + + P D E +++TW +G S Sbjct: 3605 MYKVVARNKIG--QTVARARIVFGSTPEEPDSPESDQSS---DTE-IFLTWKQPRFDGNS 3658 Query: 1798 PIIDYKVEIK-QEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 P++ Y +E K + +W K ++ L+ +++Y FR+ ARN IG S Sbjct: 3659 PVLCYSLEYKLADDIEWTKKADNIDHEFYLMRGLTPSSSYMFRLAARNAIGWS 3711 >UniRef50_UPI0000F1E3FB Cluster: PREDICTED: similar to novel immunoglobulin I-set domain containing protein; n=6; Danio rerio|Rep: PREDICTED: similar to novel immunoglobulin I-set domain containing protein - Danio rerio Length = 2140 Score = 172 bits (419), Expect = 8e-41 Identities = 173/747 (23%), Positives = 298/747 (39%), Gaps = 47/747 (6%) Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 KP V ++ C + + D+ W G EI+P S+ L I Sbjct: 1434 KPLVDTVAHKDGMITLCCELCKAKADVQWKKDGVEIIPSRRFSIRANETERS----LTIH 1489 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILS 755 + K G Y + + A L + L P+V+E L + V +GE Sbjct: 1490 RITKEDAGEYVCESKDDSTSARLRVEL---------PRVVEFLTELHNTTVMEGEDATFK 1540 Query: 756 AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 VV + W + +P+K + + H++ I K + + D T +AE G Sbjct: 1541 C-VVSPDDVQLVWLMDGEPIKPSDRFQIEQNSLCHTLIIHKVQLL-DSSRITAEAE---G 1595 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + + A + V+E LF R + + +E G L V+ + W R + Sbjct: 1596 LI-SKASLKVQEAQV------LFTKRMEAVMAEEFGEATLETEVSLES-GEVQWMRQGVV 1647 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 I P + +G L ITN+ S D G Y+C + + ++ ++ K+ K Sbjct: 1648 IQPGPKHKLSQNGCKRILTITNL-SLSDRGTYRCETLHDRTQ----VKLNVEPRKIAIRK 1702 Query: 933 HLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 + ET E +T E + SHT V W + I ++ + GR Sbjct: 1703 GMM-DVETFERETASFEVELSHTDVEGVWQKDGLRIKPNNNWRVSSNGRVHGLTLSNLTM 1761 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D G I + + LVVKET +KL D ++E+ +LE E++ DV W++ Sbjct: 1762 EDTGSIVFSAEGLRNTARLVVKETPVAIFKKLSDVRIEEESSVVLECELSRPNVDVRWQK 1821 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 +G +K K + G R L I S+ D G Y+C + D S + ++ V E E+IT Sbjct: 1822 NGIELKSSKTLRIYSM-GRKRCLQIMECSISDSGLYTCEIGDLSTSCKLEVYEHELELIT 1880 Query: 1112 RLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 L++ + + A F EL+ D W+K+GS I+ ++ I+ +G K L I + + Sbjct: 1881 GLEDLWIKEDQNAVFMCELSMEDMPGEWYKNGSRIRPTSTIKTRTEGTKHFLLICNVKAE 1940 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 D+GE + A L VEE ++ L + + + L + DVTWY+ Sbjct: 1941 DSGEIKFVSKQVESVACLEVEELPVSIVRPLRDRTALEKHR-VILECTVSSPNCDVTWYR 1999 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 + +E TE +I + L+I++ +D+ Y+ + + S KL VE +V Sbjct: 2000 ENEELESTEHMEIIQEGCYHKLVIQQVALEDEGTYSIEVGEHTSIAKLMVEAQSI--LVV 2057 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + ++ L + W +N + ++ + + LT K Sbjct: 2058 KNIEDVEVRAPETAFFLCEVSVALIKPPVWTLNGETLQSGPNVRIDNQGTVHKLTFKTTS 2117 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL 1378 + +G K G A +T+L Sbjct: 2118 SDMSGTVKF----TTGKAKTTAKLTVL 2140 Score = 168 bits (408), Expect = 2e-39 Identities = 202/888 (22%), Positives = 366/888 (41%), Gaps = 62/888 (6%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S P Q + G D++L C + P + WLF + ++PDE + + + L Sbjct: 1254 SGDPDYQEMVTGDDLILACEVSRANAP-VKWLFNEKVLIPDERTHIESQGTLRK----LT 1308 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI---EPLKSMIVRQGESVI 753 I+N+ G Y AV + + V+K+ +EPP E + + + E V Sbjct: 1309 ISNILVSDSGKYMCDAV----DDKMLTVVKV----QEPPVEFLNKEEVNLVTGYEAEPVT 1360 Query: 754 LSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L+A +V P + W K+ + + T S G T + TI P K D G YT A NS+ Sbjct: 1361 LTA-MVSRPNAQVRWLKDWTQISGERFHTASLGLTRTFTI-DPLKKLDSGEYTCDA-NSD 1417 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 E + V++ + F+ + + G I L + + + W ++ Sbjct: 1418 ---EMHFSLLVKDMRIK------FVKPLVDTVAHKDGMITLCCELCKAKA-DVQWKKDGV 1467 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-F 930 I PS + + L I + E D+G+Y C + + S AR+ +++ +V F Sbjct: 1468 EIIPSRRFSIRANETERSLTIHRITKE-DAGEYVCESKD----DSTSARLRVELPRVVEF 1522 Query: 931 VKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 + L + EG+ +C S V W + + I D +I Q Sbjct: 1523 LTELHNT-TVMEGEDATFKCVVSPDDVQLVWLMDGEPIKPSDRFQIEQNSLCHTLIIHKV 1581 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 D I + + L V+E F ++++ +E A LE E++ E+ +V W Sbjct: 1582 QLLDSSRITAEAEGLISKASLKVQEAQVLFTKRMEAVMAEEFGEATLETEVSLESGEVQW 1641 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 R G +I+P K+ + G R L I N S+ D G Y C + ++ V I Sbjct: 1642 MRQGVVIQPGP-KHKLSQNGCKRILTITNLSLSDRGTYRCETLHDRTQVKLNVEPRKIAI 1700 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 + + + + A+FE+EL+ D W KDG I+ +N+ +++ +G+ L + + Sbjct: 1701 RKGMMDVETFERETASFEVELSHTDVEGVWQKDGLRIKPNNNWRVSSNGRVHGLTLSNLT 1760 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 ++D G + TA L V+E + +L + + + + L E+ +DV W Sbjct: 1761 MEDTGSIVFSAEGLRNTARLVVKETPVAIFKKLSD-VRIEEESSVVLECELSRPNVDVRW 1819 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 K ++ ++ + S +KR L I +C+ D YTC + D +T K+EV E + Sbjct: 1820 QKNGIELKSSKTLRIYSMGRKRCLQIMECSISDSGLYTCEIGDL--STSCKLEVYEHELE 1877 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK 1349 ++ + IK + + + P EW N I+ K + L I Sbjct: 1878 LITGLEDLWIKEDQNAVFMCELSMEDMPG-EWYKNGSRIRPTSTIKTRTEGTKHFLLICN 1936 Query: 1350 VENTDAGIYKL---RLENNCGHADVEMNVTIL----DKPSPPGKPNILE--IDSSSINIC 1400 V+ D+G K ++E+ E+ V+I+ D+ + ILE + S + ++ Sbjct: 1937 VKAEDSGEIKFVSKQVESVACLEVEELPVSIVRPLRDRTALEKHRVILECTVSSPNCDVT 1996 Query: 1401 W----DEPENTGNSTII----YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 W +E E+T + II Y+ + Q++ + + TSI L + Sbjct: 1997 WYRENEELESTEHMEIIQEGCYHKLVIQQVALEDEGTYSIEVGEHTSIAKLMVEAQSILV 2056 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 + +V++ A ET + + I+ P + + + PN I+ Sbjct: 2057 VKNIEDVEVR-APETAFFLCEVSVALIKPPVWTLNGETLQSGPNVRID 2103 Score = 145 bits (352), Expect = 1e-32 Identities = 225/1036 (21%), Positives = 402/1036 (38%), Gaps = 95/1036 (9%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C ++ + ++ W G E+ DEN ++ +E D V+ T + E Sbjct: 992 LVLNCE-ISKADAEVCWFCDGMEV--DENDNLKLEDDGIYRRLVIPCTTIDDSAE----- 1043 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ---GESVILSAQVVGNPRPTIT 767 V + ++ +KI E+ P ++ +S + + G+ VIL +V + Sbjct: 1044 -YVCETADDAVTFWVKI---EEPPVKLSSSKQSGSITESFAGDPVILELEV-SRENAEVC 1098 Query: 768 WCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE---GIAETSAVIT 821 W K+ V+ + +G T ITI P +KD G+YT A + + T A +T Sbjct: 1099 WMKDGMKVEESSNITITENGLTRKITIHCPT-LKDSGIYTCNAIDDTMDFKVKITEAPVT 1157 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 + + E + + + ++ ++ + + + N V +TWY+N I +E Sbjct: 1158 ILNKDQIKNEHKVML--YDDVVMECELS-------SANGV--VTWYKNGSPIEENERFCL 1206 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSY-E 939 +G LVI + + DSG+Y A N S H VT+ V + + Y E Sbjct: 1207 EEEGTFRSLVILCAELQ-DSGEYTLDAKNDTF-SFH---VTVQEPSVKIIGNSGDPDYQE 1261 Query: 940 TEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 G +IL C+ S KW N+K + + I +G D G Sbjct: 1262 MVTGDDLILACEVSRANAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVSDSGKYM 1321 Query: 999 CIVKDQETSTMLVVKETIPEFIRKLQDFEVK--EKDVAILEVEINSETADVVWERDGEII 1056 C D + T++ V+E EF+ K + V E + L ++ A V W +D I Sbjct: 1322 CDAVDDKMLTVVKVQEPPVEFLNKEEVNLVTGYEAEPVTLTAMVSRPNAQVRWLKDWTQI 1381 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 ++ + G R I D GEY+C + + V ++ + + L + Sbjct: 1382 SGER--FHTASLGLTRTFTIDPLKKLDSGEYTCDANSDEMHFSLLVKDMRIKFVKPLVDT 1439 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 +K T EL K A V+W KDG EI S + + ++ L I+ +DAGEY Sbjct: 1440 VAHKDGMITLCCELCKAKADVQWKKDGVEIIPSRRFSIRANETERSLTIHRITKEDAGEY 1499 Query: 1177 SCEVGNSKCTAILTVEEPSI-NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSV 1235 CE + +A L VE P + F L ++ + V PD+ + + W Sbjct: 1500 VCESKDDSTSARLRVELPRVVEFLTELHNTTVMEGEDATFKCVVSPDD-VQLVWLMDGEP 1558 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295 I+ +++F + + TLII K D T S LKV+ E Sbjct: 1559 IKPSDRFQIEQNSLCHTLIIHKVQLLDSSRITAEAEGLISKASLKVQ--EAQVLFTKRME 1616 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + + TL + + +W+ +I+ K S + LTI + +D Sbjct: 1617 AVMAEEFGEATLETEV-SLESGEVQWMRQGVVIQPGPKHKLSQNGCKRILTITNLSLSDR 1675 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 G Y R E V++NV +P + I +++ E E + Sbjct: 1676 GTY--RCETLHDRTQVKLNV----------EPRKIAIRKGMMDVETFERETAS------F 1717 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE---TTEYYK 1472 VE D E + K+ + + + N + +S+ R ++ + + D + E + Sbjct: 1718 EVELSHTDV-EGVWQKDGLRIKPN-NNWRVSSNGRVHGLTLSNLTMEDTGSIVFSAEGLR 1775 Query: 1473 -----VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA 1527 V+KET + + K L ++ E + L C P V W ++G +LK++K Sbjct: 1776 NTARLVVKETPV---AIFKKLSDVRIEEESSVVLECELSR-PNVDVRWQKNGIELKSSKT 1831 Query: 1528 ----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN-EDIKQ 1582 + + Y C + G++ TSC + + + + I+ ED+ Sbjct: 1832 LRIYSMGRKRCLQIMECSISDSGLYTC----EIGDLSTSCKLEVYEHELELITGLEDLWI 1887 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K ++ +E +P WYKNG+++ T+ + I +K S + Sbjct: 1888 KEDQNAVFMCELSMEDMPGE---WYKNGSRIRPTSTIKTRTEGTKHFLLICNVKAEDSGE 1944 Query: 1643 YTIEASNTAGTSSVEV 1658 + + +EV Sbjct: 1945 IKFVSKQVESVACLEV 1960 Score = 134 bits (325), Expect = 2e-29 Identities = 127/557 (22%), Positives = 243/557 (43%), Gaps = 27/557 (4%) Query: 818 AVITVEEPTEENAEPPL-FINRFQEITVKEKGTIKLV--ARVTRNPVPSITWYRNNEIIS 874 AV + T ++ EPP+ ++ +I ++ + ++V ++R+ + W+++ + Sbjct: 865 AVFQSDNITIQSEEPPITIVDPKDDIHMERYVSEEIVLNCELSRSN-GEVQWFKDGLKLQ 923 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 ++ I + +G ++I S+ DSG+Y C AG S ++ I V FV Sbjct: 924 ETDNIRLSAEGPYRRVIIFCA-SKRDSGEYVC----DAGGDSVFFQLLITEAPVRFVSPS 978 Query: 935 QKSYET--EEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 + E + ++L C+ S W+ + E+ D+ ++ +G Sbjct: 979 ESEVEVCIMSSEKLVLNCEISKADAEVCWFCDGMEVDENDNLKLEDDGIYRRLVIPCTTI 1038 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---DVAILEVEINSETADVV 1048 D C D + + ++E + Q + E D ILE+E++ E A+V Sbjct: 1039 DDSAEYVCETADDAVTFWVKIEEPPVKLSSSKQSGSITESFAGDPVILELEVSRENAEVC 1098 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W +DG ++ N + G RK+ I ++ D G Y+C D++ +V + E P Sbjct: 1099 WMKDGMKVEESSN-ITITENGLTRKITIHCPTLKDSGIYTCNAIDDTMDFKVKITEAPVT 1157 Query: 1109 IITR--LQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 I+ + ++N+ KV + E EL+ + +V W+K+GS I+ + L +G + L I Sbjct: 1158 ILNKDQIKNEHKVMLYDDVVMECELSSANGVVTWYKNGSPIEENERFCLEEEGTFRSLVI 1217 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEFILVPANTDAYLTVEIPDE 1223 +L D+GEY+ + N + +TV+EPS+ P++ + D L E+ Sbjct: 1218 LCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGDPDYQEMVTGDDLILACEVSRA 1277 Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 V W + V+ E+ + S R L I D +Y C +D K T +KV+ Sbjct: 1278 NAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVSDSGKYMCDAVDDKMLTVVKVQ- 1336 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSK 1341 E P + ++ E E + G + + +PN + W+ + I + S+ Sbjct: 1337 -EPPVEFLNKE-EVNLVTGYEAEPVTLTAMVSRPNAQVRWLKDWTQISGERFHTASL-GL 1393 Query: 1342 SASLTIKKVENTDAGIY 1358 + + TI ++ D+G Y Sbjct: 1394 TRTFTIDPLKKLDSGEY 1410 Score = 122 bits (293), Expect = 1e-25 Identities = 111/388 (28%), Positives = 168/388 (43%), Gaps = 40/388 (10%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-------D 783 + +P +I+PL S+ V +GE S ++ G+P P + W K+ K + + + D Sbjct: 147 DNKPYFLIKPL-SLRVDRGEDAAFSCKITGDPLPQVVWEKDGKQLNEIYESAHYHVGQQD 205 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE-------------------E 824 G + I K + D GVY KA N G A T AV+ VE Sbjct: 206 GGWFQLKIFKTR-TPDGGVYMCKAVNKHGEAITGAVLLVEPIPEHREGSMTNGYTNGHYS 264 Query: 825 PTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 P A EP L +++ ++ TV E K VT P P I W RN EII PS Sbjct: 265 PQHSRAKHSKEPHLNVSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNGEIIMPSRRHL 324 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 D E + + D+G Y C ASN+ G + ++++ V F + LQ S E Sbjct: 325 IFEDREGYYTLKVLYCKQQDTGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDS-EF 383 Query: 941 EEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 E +LEC+ ++ST WY + + + + Q+G D GV C Sbjct: 384 RERDVAVLECEVPEESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTIQNVGADDDGVYLC 443 Query: 1000 IVKD-QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 + D +T L VK TI ++KL + EV E + A VE+ + D+ W +DG ++ Sbjct: 444 EMPDGGKTIAELAVKGTI---VKKLPRRLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQ 500 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 + ++ + G L NTS D G Sbjct: 501 -ETHQTIIKSFGKTHILVFVNTSYQDSG 527 Score = 120 bits (288), Expect = 6e-25 Identities = 135/641 (21%), Positives = 259/641 (40%), Gaps = 40/641 (6%) Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 +L E++ +V W +DG ++ N G R++ I S D GEY C + Sbjct: 901 VLNCELSRSNGEVQWFKDGLKLQETDN-IRLSAEGPYRRVIIFCASKRDSGEYVCDAGGD 959 Query: 1095 SCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151 S ++ + E P ++ +++ + K E++K DA V WF DG E+ +++ Sbjct: 960 SVFFQLLITEAPVRFVSPSESEVEVCIMSSEKLVLNCEISKADAEVCWFCDGMEVDENDN 1019 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP-- 1209 ++L DG ++L I +DD+ EY CE + T + +EEP + + + Sbjct: 1020 LKLEDDGIYRRLVIPCTTIDDSAEYVCETADDAVTFWVKIEEPPVKLSSSKQSGSITESF 1079 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 A L +E+ E +V W K +E++ T+ + R + I T D YTC Sbjct: 1080 AGDPVILELEVSRENAEVCWMKDGMKVEESSNITITENGLTRKITIHCPTLKDSGIYTCN 1139 Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYER---EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 +D T KV++ E P I++ ++ E+++ DV + + + W N Sbjct: 1140 AID--DTMDFKVKITEAPVTILNKDQIKNEHKVMLYDDVVMECELSS-ANGVVTWYKNGS 1196 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 I++ + + SL I E D+G Y L +N+ V + + G Sbjct: 1197 PIEENERFCLEEEGTFRSLVILCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGD 1256 Query: 1387 PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN 1446 P+ E+ + I E + N+ + + E I T + +I N+ + Sbjct: 1257 PDYQEMVTGDDLILACE-VSRANAPVKWLFNEKVLIPDERTHIESQGTLRKLTISNILVS 1315 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE----KPLKNITTEPNEDIELT 1502 S ++ AV++ K++ K+Q P VE + + +T E + LT Sbjct: 1316 DSGKYMCDAVDD-------------KMLTVVKVQEPPVEFLNKEEVNLVTGYEAEPVTLT 1362 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 + P +V W +D ++ + A+ Y C A +D E+ Sbjct: 1363 AMVSR-PNAQVRWLKDWTQISGERFHTASLGLTRTFTIDPLKKLDSGEYTCDANSD--EM 1419 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 S +V + + + + HK G L + + +V W K+G ++ + + Sbjct: 1420 HFSLLVKDMRIKFVKPLVDTV--AHKDGMITLCCELCKA--KADVQWKKDGVEIIPSRRF 1475 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 +I E + I + + + +Y E+ + + ++ + V L Sbjct: 1476 SIRANETERSLTIHRITKEDAGEYVCESKDDSTSARLRVEL 1516 Score = 115 bits (276), Expect = 2e-23 Identities = 172/818 (21%), Positives = 304/818 (37%), Gaps = 60/818 (7%) Query: 463 TEEKGWVPAQYLMDENNYTQYL--QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKH 520 T+E+ PAQ + N Q + ++ + KI + EK Q P F+ K Sbjct: 101 TQEQQTQPAQAPPPQQNDVQVIPPEQDIKMKIQQQVGVEKKKDPFQDNKPYFLIKPLSLR 160 Query: 521 TPDGSTVQFECQVEGYPRPQITW---FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 G F C++ G P PQ+ W +Q I S + + D L I + D Sbjct: 161 VDRGEDAAFSCKITGDPLPQVVWEKDGKQLNEIYESAHYHVGQQDGGWFQLKIFKTRTPD 220 Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 G + C A N G A + L+VE P+ +H + P + Sbjct: 221 GGVYMCKAVNKHGEAITGAVLLVE-PIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLN 279 Query: 638 -KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 K K V EG C + P+P+I W GE I+P I D Y + LK Sbjct: 280 VSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNGEIIMPSRR--HLIFEDREGYYT-LK 336 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 + K+ G Y A N G + L +K P + L+ R+ + +L Sbjct: 337 VLYCKQQDTGLYICAASNALGNTLSAVQLSVK---GPPVRFKRALQDSEFRERDVAVLEC 393 Query: 757 QVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGI 813 +V T + ++ + + G +TI + D+GVY + + + I Sbjct: 394 EVPEESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTI-QNVGADDDGVYLCEMPDGGKTI 452 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EI 872 AE + T+ + E V E V ++ + I W+++ ++ Sbjct: 453 AELAVKGTIVKKLPRRLE------------VMEGENAAFFVEVEQDDM-DICWFKDGLQL 499 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 +TI ++F G+ LV N + DSG +A S S + + V Sbjct: 500 QETHQTIIKSF-GKTHILVFVNTSYQ-DSGTITFMAGRSTTSSKLRVKTARHCPPICPVG 557 Query: 933 HLQKSYETEEGKTVILECQTS-----HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + + G V+L S T + + ++E+ + + + Sbjct: 558 VQMNTDCCQNG--VVLSWSPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTETGTSAEVL 615 Query: 988 XXXXXDVGVIK---CIVKDQETSTMLVVKETI-----PEFIRKLQDFEVKEKDVAILEVE 1039 G + C V S + + + P+ L++ V E + A+ +E Sbjct: 616 GDSVPCEGDFRFRICCVNKYGRSGHVEFPKVVHLAPGPKIKSPLKNAVVTEGEDAVFSIE 675 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT-SVHDEGEYSCILRDESCTA 1098 ++SE + ++ + + K HI L IR +V+D E + I +A Sbjct: 676 LSSELIGTWFLNSQQLQQSEHFSMTQSKNQHI--LRIRQVPNVYDGAEITFIATGVRDSA 733 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158 + + E+ + T L GN E+++ A V+WFKDG E+ + + + DG Sbjct: 734 SLQIKEMDTKKSTEL-------GNPIVLYCEVSQPTATVQWFKDGKELHAEDGLNIQSDG 786 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF-TLRLPEFILVPANTD-AYL 1216 +++ I+ + +G Y+C+ N T + VE P + F ++ E D L Sbjct: 787 NMRRIIIHSAEYSHSGVYTCQSNNDILTFNVNVEAPPVLFKEIKAEERQKSAMELDPVVL 846 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 T EI W+K + ++ T+ S+ T++ Sbjct: 847 TCEISQPEAPSCWFKDGVAVFQSDNITIQSEEPPITIV 884 Score = 110 bits (264), Expect = 5e-22 Identities = 130/564 (23%), Positives = 234/564 (41%), Gaps = 43/564 (7%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ V G+D +L+C++ P+PD+ W K E I P+ + + ++ L I+ Sbjct: 14 PRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVY----TLYISG 69 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 V G Y A N GE LK++ E+ Q +P ++ +Q + QV+ Sbjct: 70 VTMEDAGQYICRAKNNIGETYAAATLKVQ--EETQEQQTQPAQAPPPQQND-----VQVI 122 Query: 760 GNPRPTITWCKNNKPVKALPTKSD-GDTHSITILKPKKVK-DEGVYTLKAENSEGIAETS 817 P I K + V K D ++KP ++ D G A + + + Sbjct: 123 P-PEQDIKM-KIQQQVGVEKKKDPFQDNKPYFLIKPLSLRVDRGEDA--AFSCKITGDPL 178 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 + E+ ++ E ++ + + ++ G +L TR P + Y + E Sbjct: 179 PQVVWEKDGKQLNE--IYESAHYHVGQQDGGWFQLKIFKTRTPDGGV--YMCKAVNKHGE 234 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 IT +E + + + + +G S ++ H ++V K K Sbjct: 235 AITGAV--LLVEPIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLNVSKA-------KK 285 Query: 938 YETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXX--XXD 993 + EGK C + + W N EI R +I E R D Sbjct: 286 FTVTEGKHAKFRCYVTGKPKPEIVWKRNG-EIIMPSRRHLIFEDREGYYTLKVLYCKQQD 344 Query: 994 VGVIKCIVKDQETSTMLVVKETIP----EFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 G+ C + +T+ V+ ++ F R LQD E +E+DVA+LE E+ E+ W Sbjct: 345 TGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDSEFRERDVAVLECEVPEESISTAW 404 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 + + ++ NKY+ E++G R+L I+N D+G Y C + D T + + + I Sbjct: 405 YLEDQRLQ-HGNKYNMEQKGTWRRLTIQNVGADDDGVYLCEMPDGGKT--IAELAVKGTI 461 Query: 1110 ITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 + +L + +V +G A F +E+ + D + WFKDG ++Q ++ + GK L + Sbjct: 462 VKKLPRRLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQETHQTIIKSFGKTHILVFVNT 521 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVE 1192 D+G + G S ++ L V+ Sbjct: 522 SYQDSGTITFMAGRSTTSSKLRVK 545 Score = 99.1 bits (236), Expect = 1e-18 Identities = 115/561 (20%), Positives = 214/561 (38%), Gaps = 33/561 (5%) Query: 1110 ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIY 1166 +++ + V +G A F +T K + W ++G EI + L + ++ LK+ Sbjct: 280 VSKAKKFTVTEGKHAKFRCYVTGKPKPEIVWKRNG-EIIMPSRRHLIFEDREGYYTLKVL 338 Query: 1167 DCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 C D G Y C +GN+ L+V+ P + F L + + A L E+P+ Sbjct: 339 YCKQQDTGLYICAASNALGNTLSAVQLSVKGPPVRFKRALQDSEFRERDV-AVLECEVPE 397 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 E++ WY + ++ K+ + R L I+ DD Y C + D T E Sbjct: 398 ESISTAWYLEDQRLQHGNKYNMEQKGTWRRLTIQNVGADDDGVYLCEMPDGGKTI---AE 454 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 + + R + G + V+ + + W + +++ T K+ Sbjct: 455 LAVKGTIVKKLPRRLEVMEGENAAFFVEVEQ-DDMDICWFKDGLQLQETHQTIIKSFGKT 513 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPPGKPNILEIDSSSINICW 1401 L D+G + + + + P P G + + + + W Sbjct: 514 HILVFVNTSYQDSGTITFMAGRSTTSSKLRVKTARHCPPICPVGVQMNTDCCQNGVVLSW 573 Query: 1402 DEPENTGNSTI-IYYVVEYQEIDTTEW---ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 N NST YV+E QE+ + EW ++ + T + ++ +RFR VN Sbjct: 574 SPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTETGTSAEVLGDSVPCEGDFRFRICCVN 633 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 + S E+ KV+ P ++ PLKN ED + + TW+ Sbjct: 634 KY---GRSGHVEFPKVVH--LAPGPKIKSPLKNAVVTEGEDAVFSIELSS--ELIGTWFL 686 Query: 1518 DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577 + ++L+ ++ + Y D E+ T G++ + I Sbjct: 687 NSQQLQQSEHFSMTQSKNQHILRIRQVPNVY------DGAEI-TFIATGVRDSASLQIKE 739 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 D K+ ++G+ ++ + P V W+K+G +L + NI + I I + Sbjct: 740 MDTKKSTELGNPIVLYCEVSQ-PTATVQWFKDGKELHAEDGLNIQSDGNMRRIIIHSAEY 798 Query: 1638 SHSSKYTIEASNTAGTSSVEV 1658 SHS YT +++N T +V V Sbjct: 799 SHSGVYTCQSNNDILTFNVNV 819 Score = 90.6 bits (215), Expect = 4e-16 Identities = 131/559 (23%), Positives = 210/559 (37%), Gaps = 74/559 (13%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP + RP G+ +CQ+ G P+P + W R+ I P +++ D V TL Sbjct: 7 APRVLGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRI-TQDGKVYTL 65 Query: 569 VIREVFPEDAGTFTCVAKNAAG--FASSTTELIVE----------APLSDHGSEMTV--- 613 I V EDAG + C AKN G +A++T ++ E AP + Sbjct: 66 YISGVTMEDAGQYICRAKNNIGETYAAATLKVQEETQEQQTQPAQAPPPQQNDVQVIPPE 125 Query: 614 ----XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669 D + P F KP + VD G D C++ P P + W Sbjct: 126 QDIKMKIQQQVGVEKKKDPFQDNKPYFLIKPLSLRVDRGEDAAFSCKITGDPLPQVVWEK 185 Query: 670 KGE---EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 G+ EI + V + D + LKI + G Y AVN+ GEA VL Sbjct: 186 DGKQLNEIYESAHYHVG-QQDGGWF--QLKIFKTRTPDGGVYMCKAVNKHGEAITGAVLL 242 Query: 727 IK---------------TGEKEP----------PQV-IEPLKSMIVRQGESVILSAQVVG 760 ++ G P P + + K V +G+ V G Sbjct: 243 VEPIPEHREGSMTNGYTNGHYSPQHSRAKHSKEPHLNVSKAKKFTVTEGKHAKFRCYVTG 302 Query: 761 NPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 P+P I W +N + + + L + +++ +L K+ +D G+Y A N+ G + Sbjct: 303 KPKPEIVWKRNGEIIMPSRRHLIFEDREGYYTLKVLYCKQ-QDTGLYICAASNALGNTLS 361 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 + ++V+ P P F Q+ +E+ L V + S WY ++ + Sbjct: 362 AVQLSVKGP------PVRFKRALQDSEFRERDVAVLECEVPEESI-STAWYLEDQRLQHG 414 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 G L I NV ++ D G Y C + GK+ A + + K T VK L + Sbjct: 415 NKYNMEQKGTWRRLTIQNVGAD-DDGVYLCEMPD-GGKTI--AELAV---KGTIVKKLPR 467 Query: 937 SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQE-GRXXXXXXXXXXXXDV 994 E EG+ + + W+ + ++ H+ II+ G+ D Sbjct: 468 RLEVMEGENAAFFVEVEQDDMDICWFKDGLQLQ-ETHQTIIKSFGKTHILVFVNTSYQDS 526 Query: 995 GVIKCIVKDQETSTMLVVK 1013 G I + TS+ L VK Sbjct: 527 GTITFMAGRSTTSSKLRVK 545 Score = 56.8 bits (131), Expect = 6e-06 Identities = 60/289 (20%), Positives = 121/289 (41%), Gaps = 18/289 (6%) Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA-RVTIDVEKVTFVKHLQKSYETEEG 943 G + E++ +V E D ++ N G+S H + + +K K+ EG Sbjct: 609 GTSAEVLGDSVPCEGDFR-FRICCVNKYGRSGHVEFPKVVHLAPGPKIKSPLKNAVVTEG 667 Query: 944 KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQ-EGRXXXXXXXXXXXXDVGVIKCIVK 1002 + + + S + W+ N +++ +H + Q + + D I I Sbjct: 668 EDAVFSIELSSELIGTWFLNSQQLQQSEHFSMTQSKNQHILRIRQVPNVYDGAEITFIAT 727 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062 S L +KE + +L + +L E++ TA V W +DG+ + ++ Sbjct: 728 GVRDSASLQIKEMDTKKSTEL-------GNPIVLYCEVSQPTATVQWFKDGKELH-AEDG 779 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG- 1121 + + G++R++ I + G Y+C ++ T V VE PP + ++ ++ K Sbjct: 780 LNIQSDGNMRRIIIHSAEYSHSGVYTCQSNNDILTFNVN-VEAPPVLFKEIKAEERQKSA 838 Query: 1122 ---NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 + E+++ +A WFKDG + S++I TI ++ + I D Sbjct: 839 MELDPVVLTCEISQPEAPSCWFKDGVAVFQSDNI--TIQSEEPPITIVD 885 Score = 50.0 bits (114), Expect = 7e-04 Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 12/242 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 P+I + L+N V +G A F IEL+ + + WF + ++Q S H +T + L+I Sbjct: 653 PKIKSPLKNAVVTEGEDAVFSIELSS-ELIGTWFLNSQQLQQSEHFSMTQSKNQHILRIR 711 Query: 1167 DC-DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 ++ D E + + +A L ++E + L I+ L E+ T Sbjct: 712 QVPNVYDGAEITFIATGVRDSASLQIKEMDTKKSTELGNPIV--------LYCEVSQPTA 763 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 V W+K + + + SD R +II YTC + T + VE Sbjct: 764 TVQWFKDGKELHAEDGLNIQSDGNMRRIIIHSAEYSHSGVYTCQSNNDILTFNVNVEAPP 823 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 K + E + D +L + P+ W + + + + +I S+ + Sbjct: 824 VLFKEIKAEERQKSAMELDPVVLTCEISQPEAPSCWFKDGVAVFQSDNI--TIQSEEPPI 881 Query: 1346 TI 1347 TI Sbjct: 882 TI 883 Score = 44.8 bits (101), Expect = 0.026 Identities = 22/86 (25%), Positives = 38/86 (44%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G + ++ I G P P+VIW + + + Y IT K + I + + +Y Sbjct: 20 KCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYISGVTMEDAGQYI 79 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPE 1670 A N G + TLKV ++ + + Sbjct: 80 CRAKNNIGETYAAATLKVQEETQEQQ 105 Score = 43.2 bits (97), Expect = 0.081 Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 4/160 (2%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ W+K+G +L+ + I + KT ++ S T A + +S + V Sbjct: 489 DICWFKDGLQLQETHQTIIKSFGKTHILVFVNTSYQDSGTITFMAGRSTTSSKLRVKTAR 548 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKP-PLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 + P P G + + + V + W P P + Y +E+ E + W + + Sbjct: 549 HCPPICPVGVQMNTDCCQNGVVLSWSPSPNLQNSTTKSVYVLERQEVGSQEWQRCLTTET 608 Query: 1722 DVETYCIQKLNENCE--YMFRVIAQNPVGFSEALESEPIV 1759 + + CE + FR+ N G S +E +V Sbjct: 609 GTSAEVLGD-SVPCEGDFRFRICCVNKYGRSGHVEFPKVV 647 Score = 41.9 bits (94), Expect = 0.19 Identities = 42/193 (21%), Positives = 82/193 (42%), Gaps = 22/193 (11%) Query: 1512 KVTWYRDGKKLKTAK--ATYENRXXXXXXXX--XXXXXXXYKCIAFNDHGEVETSCVVGI 1567 +V W +DG K++ + EN Y C A +D + + V I Sbjct: 1096 EVCWMKDGMKVEESSNITITENGLTRKITIHCPTLKDSGIYTCNAIDDTMDFK----VKI 1151 Query: 1568 QQKPVITISNEDIKQKHKVG--DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 + PV ++ + IK +HKV D+ ++ + V WYKNG+ +E ++ + + + Sbjct: 1152 TEAPVTILNKDQIKNEHKVMLYDDVVMECELSSANGV-VTWYKNGSPIEENERFCLEEEG 1210 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSV---EVTLKVYDKPSKP--------EGPVI 1674 + I + S +YT++A N + V E ++K+ P + ++ Sbjct: 1211 TFRSLVILCAELQDSGEYTLDAKNDTFSFHVTVQEPSVKIIGNSGDPDYQEMVTGDDLIL 1270 Query: 1675 MREISRESVTIEW 1687 E+SR + ++W Sbjct: 1271 ACEVSRANAPVKW 1283 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/80 (31%), Positives = 37/80 (46%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P+++ Y R +K G+D L PQP+ W ++ I + + D K +L I Sbjct: 8 PRVLGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYI 67 Query: 1348 KKVENTDAGIYKLRLENNCG 1367 V DAG Y R +NN G Sbjct: 68 SGVTMEDAGQYICRAKNNIG 87 Score = 39.5 bits (88), Expect = 0.99 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Query: 1200 LRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L P +LV TDA L +I D DV W +K I ++ + D K TL I Sbjct: 11 LGYPRPVLVKCGTDAVLKCQIGGDPQPDVIWERKNESIHPEGRYRITQDGKVYTLYISGV 70 Query: 1259 TEDDQCEYTC 1268 T +D +Y C Sbjct: 71 TMEDAGQYIC 80 >UniRef50_UPI0000DB720F Cluster: PREDICTED: similar to CG14964-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG14964-PA - Apis mellifera Length = 1434 Score = 172 bits (419), Expect = 8e-41 Identities = 108/391 (27%), Positives = 184/391 (47%), Gaps = 15/391 (3%) Query: 1381 PSPPGKPNIL----EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNI-T 1434 P+PPGKP ++ E + I W+ + G S I+ Y+VE++ + + W+ S + T Sbjct: 30 PAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLCT 89 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITT 1493 + ++ L+ Y+FR A N V +S SE ++ V + + S P + +K+ T Sbjct: 90 FPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTV 149 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYK 1549 NE E F G P PK+ W++DG ++ +T T + K Sbjct: 150 LENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIK 209 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIWYK 1608 C A N G T + ++ P I + + DE + V + G PPP VIWY Sbjct: 210 CTATNRAGHASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYH 269 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 +G + +D+ + + + S+++I + KR +Y ++A N G + + V D+P+ Sbjct: 270 DGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAINKLGEDTSSFLVTVTDRPAA 329 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P + + R SV++ W+ P DDGG ++ Y +E + + W+K A R + + Sbjct: 330 PGKATVTMTLGR-SVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLK-ATTSRQTKA-TL 386 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 +L E EY FRV A+NP G SE E ++ Sbjct: 387 SELIEGSEYKFRVKAENPYGVSEPSEESDVI 417 Score = 109 bits (262), Expect = 8e-22 Identities = 65/248 (26%), Positives = 112/248 (45%), Gaps = 6/248 (2%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-E 1285 + W+K I + + +I++ K L+I + +D+ E C + K ++ E Sbjct: 169 IAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTKARLILE 228 Query: 1286 FPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSK 1341 PPKI YE ++ + L V P P+ W + +++ +H S+D + Sbjct: 229 APPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGE 288 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 S L I + D G Y ++ N G VT+ D+P+ PGK + S+++ W Sbjct: 289 SI-LKIPDAKRVDRGEYVVKAINKLGEDTSSFLVTVTDRPAAPGKATVTMTLGRSVSLTW 347 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 EPE+ G I Y+VEY I W+ +T+ ++ L S Y+FR A N + Sbjct: 348 QEPEDDGGCKIGTYIVEYYRIGWDVWLKATTSRQTKATLSELIEGSEYKFRVKAENPYGV 407 Query: 1462 SDASETTE 1469 S+ SE ++ Sbjct: 408 SEPSEESD 415 Score = 77.4 bits (182), Expect = 4e-12 Identities = 58/227 (25%), Positives = 103/227 (45%), Gaps = 13/227 (5%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 +F+ V ++R E S P+ + ++ PQ +K V + E + G+ Sbjct: 105 QFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTVLENEQAEFVVRFTGS 164 Query: 762 PRPTITWCKNNKPV-KALPTKSDGDT-HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P P I W K+ + + T+ ++ S+ ++ + DEG A N G A T A Sbjct: 165 PLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTKAR 224 Query: 820 ITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 + +E P P + + R E + ++ TI+L + P PS+ WY + E++S E Sbjct: 225 LILEAP------PKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSSDE 278 Query: 878 T-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + ++ DGE+I L I + +D G+Y A N G+ + VT+ Sbjct: 279 RHVFESMDGESI-LKIPDA-KRVDRGEYVVKAINKLGEDTSSFLVTV 323 Score = 64.5 bits (150), Expect = 3e-08 Identities = 46/181 (25%), Positives = 87/181 (48%), Gaps = 9/181 (4%) Query: 803 YTLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 + ++A+N+ G++ S + T + A P F ++ TV E + V R T +P Sbjct: 106 FRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTVLENEQAEFVVRFTGSP 165 Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 +P I W+++ EI S T G+++ L+ + D G+ KC A+N AG +S A Sbjct: 166 LPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALN--DEGEIKCTATNRAGHASTKA 223 Query: 920 RVTIDV-EKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREII 976 R+ ++ K+ + + E+ +T+ L+ + S WYH+ + +S D R + Sbjct: 224 RLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPSVIWYHDGEVVSS-DERHVF 282 Query: 977 Q 977 + Sbjct: 283 E 283 Score = 62.1 bits (144), Expect = 2e-07 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 2/92 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P+ P V+ + RSV+L W EPE +GG I YI+E+ + W K T + Sbjct: 327 PAAPGKATVTMTLGRSVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLKATT--SRQTKA 384 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + + E E FR+ AEN GVS P+E V Sbjct: 385 TLSELIEGSEYKFRVKAENPYGVSEPSEESDV 416 Score = 60.1 bits (139), Expect = 7e-07 Identities = 54/196 (27%), Positives = 77/196 (39%), Gaps = 13/196 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + K V E R P P IAW G EI + ES S Sbjct: 138 PQFDLEVKDTTVLENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGK----S 193 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGE 750 VL I EG A NR G AS L ++ PP++ P + ++ Q E Sbjct: 194 VLLIHQTALNDEGEIKCTATNRAGHASTKARLILEA----PPKIRLPRQYEDGLLFEQDE 249 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 ++ L + G P P++ W + + V + D SI + K D G Y +KA Sbjct: 250 TIRLKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAI 309 Query: 809 NSEGIAETSAVITVEE 824 N G +S ++TV + Sbjct: 310 NKLGEDTSSFLVTVTD 325 Score = 56.8 bits (131), Expect = 6e-06 Identities = 79/401 (19%), Positives = 144/401 (35%), Gaps = 24/401 (5%) Query: 1666 PSKPEGPVIMR---EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P+ P P+++ E + V I W+ +GG + Y +E + W++ Sbjct: 30 PAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLCT 89 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXXXXXX 1778 + L Y FRV AQN VG S E S+P+ + ++ P Sbjct: 90 FPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTVTLQRSVASAPQFDLEVKDTTV 149 Query: 1779 IDNESV-YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 ++NE ++ F EI ++ + I + ++N + Sbjct: 150 LENEQAEFVVRFTGSPLPKIAWFKDGFEIFSS-RRTRIITESGKSVLLIHQTALNDEGEI 208 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 + A N G + S I + PR + + T++ + P Sbjct: 209 KCTATNRAG----HASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPS 264 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 + + + V ++ G S+ + I + K D + + A N +G T S Sbjct: 265 VIWYHDGEVVSSDERHVFESMDGESILK--IPDAKRVDRGEYVVKAINKLGED--TSSFL 320 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 V + P T + + G ++ +T W PE DGG + Y + + +W++ Sbjct: 321 VTVTDRPAAPGKATVTMTL---GRSVSLT-WQEPEDDGGCKIGTYIVEYYRIGWDVWLKA 376 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 K + +L E Y R+ A N G+SEP E + Sbjct: 377 --TTSRQTKATLSELIEGSEYKFRVKAENPYGVSEPSEESD 415 Score = 56.0 bits (129), Expect = 1e-05 Identities = 63/271 (23%), Positives = 111/271 (40%), Gaps = 23/271 (8%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 G P P++ W+K+G ++ + + I T+ SV+ I + + + A+N AG +S + Sbjct: 163 GSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLLIHQTALNDEGEIKCTATNRAGHASTK 222 Query: 1658 VTLKVYDKPSK-------PEGPVIMR-EISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 L + + P K +G + + E R V++ +PP + + E D Sbjct: 223 ARL-ILEAPPKIRLPRQYEDGLLFEQDETIRLKVSLAGRPPPS----VIWYHDGEVVSSD 277 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 + D + ++ ++++ EY+ + I N +G E + T D P+ Sbjct: 278 ERHVFESMDGESILKIPDAKRVDRG-EYVVKAI--NKLG-----EDTSSFLVTVTDRPAA 329 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQK 1828 + SV +TW E +GG I Y VE + G W A + + Sbjct: 330 PGKATVTMTL-GRSVSLTWQEPEDDGGCKIGTYIVEYYRIGWDVWLKATTSRQTKATLSE 388 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 L + Y+FR+ A N G S P D I I Sbjct: 389 LIEGSEYKFRVKAENPYGVSEPSEESDVIFI 419 Score = 48.8 bits (111), Expect = 0.002 Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 11/191 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P+ +++ V + +A F + T G L + WFKDG EI S ++ + K L Sbjct: 138 PQFDLEVKDTTVLENEQAEFVVRFT-GSPLPKIAWFKDGFEIFSSRRTRIITESGKSVLL 196 Query: 1165 IYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVE 1219 I+ L+D GE C G++ A L +E P I + + +L + L V Sbjct: 197 IHQTALNDEGEIKCTATNRAGHASTKARLILEAPPKIRLPRQYEDGLLFEQDETIRLKVS 256 Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 + V WY V+ E+ S + L I D+ EY ++ + T Sbjct: 257 LAGRPPPSVIWYHDGEVVSSDERHVFESMDGESILKIPDAKRVDRGEYVVKAINKLGEDT 316 Query: 1277 TKLKVEVVEFP 1287 + V V + P Sbjct: 317 SSFLVTVTDRP 327 Score = 47.6 bits (108), Expect = 0.004 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F +++ + +F + G P P+I WF+ I S+ ++ + + L Sbjct: 137 APQFDLEVKDTTVLENEQAEFVVRFTGSPLPKIAWFKDGFEIFSSRRTRIITESGK-SVL 195 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +I + D G C A N AG AS+ LI+EAP Sbjct: 196 LIHQTALNDEGEIKCTATNRAGHASTKARLILEAP 230 Score = 42.7 bits (96), Expect = 0.11 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Query: 1965 VPSPPTAPLEIRMVGSN---IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 +P+PP P+ I + +V W +GG+ ++GY + R + W+ Sbjct: 29 LPAPPGKPILIPGADESQPDVVAIRWERSPSNGGSAIVGYLVEHRRLGSQHWVRSTPGLC 88 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + + L Y R+ A+N +GLS P E +P V Sbjct: 89 TFPELTLSGLEPGWRYQFRVRAQNAVGLSRPSEISDPLTV 128 Score = 42.7 bits (96), Expect = 0.11 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 14/127 (11%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-----EGSDIL 652 LI + L+D G E+ A ++ PP + P+ QY D + I Sbjct: 196 LIHQTALNDEG-EIKCTATNRAGHASTKARLILEAPPKI-RLPR-QYEDGLLFEQDETIR 252 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 L+ L P P + W GE + DE ++ +++ + S+LKI + K+ G Y V Sbjct: 253 LKVSLAGRPPPSVIWYHDGEVVSSDERHVFESMDGE-----SILKIPDAKRVDRGEYVVK 307 Query: 712 AVNREGE 718 A+N+ GE Sbjct: 308 AINKLGE 314 >UniRef50_Q00872 Cluster: Myosin-binding protein C, slow-type; n=67; Euteleostomi|Rep: Myosin-binding protein C, slow-type - Homo sapiens (Human) Length = 1141 Score = 172 bits (418), Expect = 1e-40 Identities = 116/437 (26%), Positives = 202/437 (46%), Gaps = 13/437 (2%) Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 VE+ +V W ++G+ I+P KY FE +G R L+I N + D+ EY DE C+ Sbjct: 274 VELADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 332 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI--QFSNHIQLT 1155 E+ V E P + +L++ G + E E+++ DA V+WFK+G EI + ++ Sbjct: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIR 392 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 ++GKK L I DA EYS + +A L+V+ + L + V + Sbjct: 393 VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD-QTVNLGKEIC 451 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 L EI E + W K ++++++ ++ + L+I +D+ +Y Sbjct: 452 LKCEI-SENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510 Query: 1276 TTKLKVEVVEFPPKIV----DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKK 1330 T KV V++ PPKI+ D + + G+ + L + P P W K I++ Sbjct: 511 TLPAKVHVID-PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + S++L I E D+G+Y + L+N G A + V ++D P PP P + Sbjct: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVT 629 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK--TNSS 1448 E+ + W+ P G S I+ Y +E ++ ++ W+ + +T+ + K + Sbjct: 630 EVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA 689 Query: 1449 YRFRAYAVNEVDISDAS 1465 Y R +AVN + IS S Sbjct: 690 YEVRIFAVNAIGISKPS 706 Score = 116 bits (280), Expect = 5e-24 Identities = 146/647 (22%), Positives = 268/647 (41%), Gaps = 48/647 (7%) Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXX 984 + F K L +Y+ ++G V + + + KWY N +EI +G Sbjct: 250 KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 309 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 D D++ ST L V+E ++L+D + LE E++ + Sbjct: 310 FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 369 Query: 1045 ADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 A+V W ++G EII K++Y G L I + D EYS + +A+++V Sbjct: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVD 429 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 P +I+T L +Q VN G + + E+++ + +W K+G +Q S+ +++ G+ KL Sbjct: 430 LKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKL 488 Query: 1164 KIYDCDLDDAGEY--SCEVGNSKCTA-ILTVEEPSINFT-LRLPEFILVPANTDAYLTVE 1219 I + +D G+Y + + N A + ++ P I L + V A L + Sbjct: 489 VIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 548 Query: 1220 IPDETLDVTWYKK--KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKS 1275 I E + + K+++E + + S TL+I DD Y L + ++ Sbjct: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608 Query: 1276 TTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLL-VDYQAFP--QPNDEWIVNSKIIKKC 1331 +KV+VV+FP P + E G D ++ + A+ P + + K + Sbjct: 609 HASIKVKVVDFPDPPVAPTVTEV----GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664 Query: 1332 KHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + + + D K + KK+ A ++ N G + M + P +L Sbjct: 665 RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLL 724 Query: 1391 EIDS---SSINICWDEPENTGNSTIIYYVVEY------------------QEIDTTEWIS 1429 +DS +++ + W P++ G + + YV+EY ++ +WI Sbjct: 725 TVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784 Query: 1430 VKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA---SETTEYYKVIKETKIQSPTV 1484 I KT+ +I L T++ R AVN S+ S+ ++I+ KI+ P Sbjct: 785 ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 844 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 K + E + L F G P+P++TW +DG ++ + N Sbjct: 845 LK--QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 889 Score = 94.7 bits (225), Expect = 2e-17 Identities = 55/187 (29%), Positives = 96/187 (51%), Gaps = 6/187 (3%) Query: 1567 IQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 I + P I I +KQ + +VG+ + +G P PE+ W K+G +++ + + NI Sbjct: 833 IIEPPKIRIPRH-LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNS 890 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 E ++I I++ +RSHS KY ++ + + +++ D+P P+ V + ++ E+V Sbjct: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVA 949 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + W PP DDG +T Y I+K + + W V + I +L EY FRV ++ Sbjct: 950 LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA-TITELVIGNEYYFRVFSE 1008 Query: 1745 NPVGFSE 1751 N G SE Sbjct: 1009 NMCGLSE 1015 Score = 94.3 bits (224), Expect = 3e-17 Identities = 74/308 (24%), Positives = 142/308 (46%), Gaps = 23/308 (7%) Query: 1282 EVVEFPPKI--VDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 E++E PPKI + ++ I+R G V L++ +Q P+P W + I K + + Sbjct: 832 EIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 ++ + + I+K E + +G Y L+++ + +++ I+D+P PP I ++ ++ Sbjct: 891 ETDTI-IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 949 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVN 1457 + W P++ GN+ I Y ++ + + EW +V ++ +T +I L + Y FR ++ N Sbjct: 950 LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1009 Query: 1458 EVDIS-DASETTEYYKVIKETKI------------QSPTVEKPLKNITTEPNEDIELTCI 1504 +S DA+ T E + ++ KI ++P +PL N + L C Sbjct: 1010 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1069 Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATYENRX--XXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P+PK+TW ++ + + N+ Y C A ND G VE Sbjct: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1129 Query: 1561 TSCVVGIQ 1568 C + ++ Sbjct: 1130 IECKLEVK 1137 Score = 87.4 bits (207), Expect = 4e-15 Identities = 60/228 (26%), Positives = 108/228 (47%), Gaps = 11/228 (4%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYT 1644 G++ + I G PPP+ +W + G+K + I T+ +S + I +R S Y Sbjct: 540 GNKLRLEIPISGEPPPKAMWSR-GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYH 598 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 I N AG + + +KV D P P P + E+ + + W+PP DGG + Y IE Sbjct: 599 INLKNEAGEAHASIKVKVVDFPDPPVAPTVT-EVGDDWCIMNWEPPAYDGGSPILGYFIE 657 Query: 1705 KHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT 1762 + + ++RW+++ D+ ++ T+ +K+ E Y R+ A N +G S+ ++ S P V Sbjct: 658 RKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 716 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 P+ + + +V + W P + G + + Y +E EG Sbjct: 717 VTSPPT----LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760 Score = 67.7 bits (158), Expect = 3e-09 Identities = 87/365 (23%), Positives = 144/365 (39%), Gaps = 19/365 (5%) Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 V + G ++ V + +P + WY+N + I PS G L I N DS Sbjct: 264 VDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYH 962 Y +AG + + + K L+ + G+ V LEC+ S + KW+ Sbjct: 323 YV-----TAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEVSEDDANVKWFK 376 Query: 963 NKKE-ISGMDHREIIQ-EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI 1020 N +E I G R I+ EG+ D + ++S L V + + Sbjct: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436 Query: 1021 RKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 L D V L+ EI SE W ++G ++ + ++ +G I KL I N Sbjct: 437 TPLTDQTVNLGKEICLKCEI-SENIPGKWTKNGLPVQ-ESDRLKVVHKGRIHKLVIANAL 494 Query: 1081 VHDEGEYSCILRDESCT--AEVTVVELPPEIITRLQNQK---VNKGNKATFEIELT-KGD 1134 DEG+Y + T A+V V++ P I+ L V GNK EI ++ + Sbjct: 495 TEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554 Query: 1135 ALVRWFK-DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 W + D + ++ S I+ L I + DD+G Y + N A +++ Sbjct: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614 Query: 1194 PSINF 1198 ++F Sbjct: 615 KVVDF 619 Score = 67.7 bits (158), Expect = 3e-09 Identities = 40/132 (30%), Positives = 67/132 (50%), Gaps = 7/132 (5%) Query: 1929 NIKEKDEI-IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 +I E+D+ ++ I+ +N G + S+++ K P PP AP + VG + + +W Sbjct: 587 DIAERDDSGVYHINLKNEAGEA----HASIKV-KVVDFPDPPVAPT-VTEVGDDWCIMNW 640 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P +DGG+P+LGY I + + WM + F + + E Y +RI+A N I Sbjct: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700 Query: 2048 GLSEPLESDEPF 2059 G+S+P PF Sbjct: 701 GISKPSMPSRPF 712 Score = 66.1 bits (154), Expect = 1e-08 Identities = 160/772 (20%), Positives = 262/772 (33%), Gaps = 71/772 (9%) Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 VE+ D L+V WYK I + K+ +R L I C D EY D K +T Sbjct: 274 VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCST 333 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHT-K 1335 +L V PP +V + E + L + N +W N + II K + Sbjct: 334 EL---FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395 ++ K L I+ DA Y + A + +++ L K P + + Sbjct: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL-KILTPLTDQTVNLGKE 449 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 C G T V QE D + + I K + + Y F A Sbjct: 450 ICLKCEISENIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 507 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 N V + + K+I + TV T + L G P PK W Sbjct: 508 YN-VTLPAKVHVIDPPKIILDGLDADNTV-------TVIAGNKLRLEIPISGEPPPKAMW 559 Query: 1516 YRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 R K + +Y + Y N+ GE S V + Sbjct: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619 Query: 1571 PVITISNEDIKQKHKVGDEWLVT----AVIEGIPPPEVIWYKNGNKLENDKEYNITTKE- 1625 P ++ +VGD+W + +G P ++ Y K + + + Sbjct: 620 PDPPVA----PTVTEVGDDWCIMNWEPPAYDGGSP--ILGYFIERKKKQSSRWMRLNFDL 673 Query: 1626 -KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EISRES 1682 K + K++ + + I A N G S + + + + P ++ ++ + Sbjct: 674 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT 733 Query: 1683 VTIEWKPPLDDGGLELTKYAIE---------KHEPDNNR---------WIKVADVDR-DV 1723 VT+ W+PP G L Y +E K +N WI VA+ D D Sbjct: 734 VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDK 792 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + I L + + RV A N G SE S+PI++K ++ P + Sbjct: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL------K 846 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 YI N +I ++ + + E K I+ +T R R Sbjct: 847 QTYIRRVGEAVN---LVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 903 Query: 1843 NEIGTSLPYTSDDKITIGKTLT-----PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 + G DK ++ P P+ + + +V L WT P+ +G + I Sbjct: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 T Y I+ K W ++ I + +E FR+ +EN G+S Sbjct: 964 TGYTIQKADKKSMEWFTVIEHYHRT-SATITELVIGNEYYFRVFSENMCGLS 1014 Score = 60.9 bits (141), Expect = 4e-07 Identities = 37/111 (33%), Positives = 53/111 (47%), Gaps = 4/111 (3%) Query: 491 KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550 KI K PV+E + S AP+F + L + G C V G P+P+ITW + I Sbjct: 1031 KIYKNPVYE---DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087 Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 ++M + + V TL IR+ P D GT+ C A N G +L V+ Sbjct: 1088 VDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137 Score = 60.1 bits (139), Expect = 7e-07 Identities = 62/281 (22%), Positives = 111/281 (39%), Gaps = 25/281 (8%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVAIESDMHMYCSVLKITNVKKFQE 705 G + LEC V+ + ++ W GEEI+ P + +E H +L I K Sbjct: 356 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH----ILIIEGATKADA 410 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 Y+V+ + A L + LK P +++ PL V G+ + L ++ N Sbjct: 411 AEYSVMTTGGQSSAKLSVDLK-------PLKILTPLTDQTVNLGKEICLKCEISENIPG- 462 Query: 766 ITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 W KN PV+ L G H + I +DEG Y A ++ + A + V Sbjct: 463 -KWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVF-APDAYNVT-LPAKVHV 518 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 +P + + ++ +TV ++L ++ P P W R ++ I + Sbjct: 519 IDPPKIILDG---LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + ++ ++ DSG Y N AG++ +V + Sbjct: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616 Score = 58.4 bits (135), Expect = 2e-06 Identities = 66/245 (26%), Positives = 94/245 (38%), Gaps = 31/245 (12%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + I +NE G + + K+ + PP P V+E + W P +GGSP Sbjct: 597 YHINLKNEAGEA---HASIKVKVVDFPDPPVAP---TVTEVGDDWCIMNWEPPAYDGGSP 650 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF--RISAENTVGVSLPTES 1954 I Y IE K + W ++ E E K + + + RI A N +G+S P S Sbjct: 651 ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP--S 706 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI----------- 2003 R V SPPT L + V V W P+ G A L GY + Sbjct: 707 MPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765 Query: 2004 -------AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 A D+ W+ K ++ KF I L + +R+ A N G SEP Sbjct: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825 Query: 2057 EPFKV 2061 +P V Sbjct: 826 QPILV 830 Score = 46.0 bits (104), Expect = 0.011 Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 2/93 (2%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 E P +PL + G + L+ V GNP+P ITW KN + P + L Sbjct: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1104 Query: 793 KPKKVK--DEGVYTLKAENSEGIAETSAVITVE 823 + +K D G Y KA N G E + V+ Sbjct: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 2/101 (1%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP + G N+ +T W P+ DG A + GY I D W V + + Sbjct: 932 PGPPQIVKIEDVWGENVALT-WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTS 989 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 I +L + Y R+++ N GLSE + VI +G Sbjct: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030 Score = 38.3 bits (85), Expect = 2.3 Identities = 17/67 (25%), Positives = 31/67 (46%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + G P P++ W KN + +D Y + + + + I++ Y +A N GT Sbjct: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1129 Query: 1656 VEVTLKV 1662 +E L+V Sbjct: 1130 IECKLEV 1136 Score = 37.5 bits (83), Expect = 4.0 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 5/91 (5%) Query: 733 EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHS 788 EPP++ P LK +R+ GE+V L G PRP +TW K+ + K + +T + Sbjct: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 I ++ + G Y L+ + + ET+++ Sbjct: 895 IIFIRKAERSHSGKYDLQVK-VDKFVETASI 924 >UniRef50_Q7ZWM9 Cluster: LOC398550 protein; n=2; Xenopus|Rep: LOC398550 protein - Xenopus laevis (African clawed frog) Length = 888 Score = 170 bits (414), Expect = 3e-40 Identities = 168/694 (24%), Positives = 288/694 (41%), Gaps = 44/694 (6%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ + G D++L C L + P + WL GEE+V + + + +H L I N Sbjct: 183 PEQHLLMTGDDLVLTCEL-SRPNFKVRWLRNGEEMVSAGRVKI-LARGVHRQ---LTIQN 237 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVILSA 756 V+ GTYT A + ++ + E P+V+E L+++ V +GE+ Sbjct: 238 VRPADSGTYTCDAGTDQMHTAVYV---------EAPRVVEFVTELQNVTVLEGETASFKC 288 Query: 757 QVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 +V + W N PV K T ++G HS+ IL ++ D G T N+EG+ Sbjct: 289 -MVSPDNVDLRWELNGSPVYSDKRFSTTNNGMCHSL-ILHSCRLSDSGKITA---NAEGL 343 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + A + V+E LF Q++ +E+ + L +VTR I W + +I Sbjct: 344 I-SRAKLRVQEAQV------LFAQGLQDMEAEEEQDLLLQVQVTREQA-EIHWVKQGVVI 395 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 PS T G L I V + D G Y C + + + R+ + ++ K Sbjct: 396 QPSPKYTLQASGCTHSLTIHGVQAS-DRGRYSCESLHDRTE----CRLNVIPRSISVKKG 450 Query: 934 LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 L K + EG +V + SH + +W+ ++ D I GR Sbjct: 451 L-KDIKCVEGSSVDFTVEMSHDGLVGEWWKGGVRLTNDDQCTIRSSGRQHFLHLSDLTIP 509 Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 D VI I T+ L V E + QDF V E A + E++ + A V W++D Sbjct: 510 DSSVIAFITDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGAATFQCEVSRQDATVTWDKD 569 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112 G + P + G R L + D G Y+C + D + A + V+E P+++ Sbjct: 570 GVQLVPNATCRMYSV-GRRRILQLSQCGPSDAGIYTCHMGDINACATLRVLEQEPQMLKD 628 Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 LQ+ + + A F E++ A WFK+G ++Q SN ++ +G++ L I +D Sbjct: 629 LQDVDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVSNTTKIRQEGRRHFLLICGAQCED 688 Query: 1173 AGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 AGE + + + TA L V+E + L + + + L ++ V W + Sbjct: 689 AGEITFKARRLQSTARLRVKEIPVRIVKALRDRTALEGHR-VVLECKVNPPRAQVKWLQG 747 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292 I + K+ + ++ LII +D+ YT + + +L VE + +I Sbjct: 748 GREIFPSAKYQICNEDGFHKLIINDVAPEDEDMYTMSTAGGQCSARLLVEGLAI--QISR 805 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 + R+K D D +W +N + Sbjct: 806 GLSDVRVKAPEDACFTCDVSLPLSRPAQWSLNGE 839 Score = 124 bits (299), Expect = 3e-26 Identities = 150/685 (21%), Positives = 268/685 (39%), Gaps = 36/685 (5%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + + C L + D+ WL G+E+ P ENI + MH L+ +++ G Sbjct: 99 GDPLSIHCEL-SRNSSDLRWLKDGDEVTPTENIIMEKLGTMH----TLRFLSIQAEDAGQ 153 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y G S +K+ + ++ G+ ++L+ ++ P + Sbjct: 154 YHC----NVGADSRVFTVKVDDPPVSIVGNTGTPEQHLLMTGDDLVLTCEL-SRPNFKVR 208 Query: 768 WCKNNKP-VKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W +N + V A K + G +TI + D G YT A G + + VE Sbjct: 209 WLRNGEEMVSAGRVKILARGVHRQLTIQNVRPA-DSGTYTCDA----GTDQMHTAVYVEA 263 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P F+ Q +TV E T V+ + V + W N + + + + Sbjct: 264 PRVVE-----FVTELQNVTVLEGETASFKCMVSPDNV-DLRWELNGSPVYSDKRFSTTNN 317 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 G L++ + DSG + +N+ G S A++ + +V F + LQ E EE + Sbjct: 318 GMCHSLILHSCRLS-DSGK---ITANAEGLISR-AKLRVQEAQVLFAQGLQ-DMEAEEEQ 371 Query: 945 TVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 ++L+ Q T W I + G D G C Sbjct: 372 DLLLQVQVTREQAEIHWVKQGVVIQPSPKYTLQASGCTHSLTIHGVQASDRGRYSCESLH 431 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 T L V + L+D + E VE++ + W + G + ++ Sbjct: 432 DRTECRLNVIPRSISVKKGLKDIKCVEGSSVDFTVEMSHDGLVGEWWKGG-VRLTNDDQC 490 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 G L++ + ++ D + I TA++TV+E P I Q+ VN+G Sbjct: 491 TIRSSGRQHFLHLSDLTIPDSSVIAFITDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGA 550 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ATF+ E+++ DA V W KDG ++ + ++ G+++ L++ C DAG Y+C +G+ Sbjct: 551 ATFQCEVSRQDATVTWDKDGVQLVPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMGDI 610 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 A L V E L + + + N +A E+ W+K ++ + Sbjct: 611 NACATLRVLEQEPQMLKDLQD-VDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVSNTTK 669 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 + + ++ L+I +D E T +ST +L+V+ E P +IV R+ G Sbjct: 670 IRQEGRRHFLLICGAQCEDAGEITFKARRLQSTARLRVK--EIPVRIVKALRDRTALEGH 727 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKII 1328 V L P+ +W+ + I Sbjct: 728 RVVLECKVNP-PRAQVKWLQGGREI 751 Score = 99 bits (238), Expect = 7e-19 Identities = 125/615 (20%), Positives = 240/615 (39%), Gaps = 38/615 (6%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 EG +C +V+ D+ W G + D+ S C L + + + G Sbjct: 280 EGETASFKC-MVSPDNVDLRWELNGSPVYSDKRFSTTNNG----MCHSLILHSCRLSDSG 334 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 T N EG S K++ E + + L+ M + + ++L QV + I Sbjct: 335 KITA---NAEGLISRA---KLRVQEAQV-LFAQGLQDMEAEEEQDLLLQVQVT-REQAEI 386 Query: 767 TWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W K ++ P ++ G THS+TI + D G Y+ ++ + + + Sbjct: 387 HWVKQGVVIQPSPKYTLQASGCTHSLTI-HGVQASDRGRYSCESLHDRTECRLNVI---- 441 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P + + L ++I E ++ ++ + + W++ ++ + T Sbjct: 442 -PRSISVKKGL-----KDIKCVEGSSVDFTVEMSHDGLVG-EWWKGGVRLTNDDQCTIRS 494 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 G L ++ D I +++ + A++T+ +T + Q + EG Sbjct: 495 SGRQHFLHLS--DLTIPDSSVIAFITDTLRTT---AQLTVIEHPLTITQPPQ-DFVVNEG 548 Query: 944 KTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 +C+ S +T W + ++ + GR D G+ C + Sbjct: 549 GAATFQCEVSRQDATVTWDKDGVQLVPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMG 608 Query: 1003 DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNK 1062 D L V E P+ ++ LQD ++ E + A+ E++ A W ++GE ++ N Sbjct: 609 DINACATLRVLEQEPQMLKDLQDVDIAENENAVFMCEVSCAQAKGEWFKNGEQVQVS-NT 667 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGN 1122 + G L I D GE + R TA + V E+P I+ L+++ +G+ Sbjct: 668 TKIRQEGRRHFLLICGAQCEDAGEITFKARRLQSTARLRVKEIPVRIVKALRDRTALEGH 727 Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + E ++ A V+W + G EI S Q+ + KL I D +D Y+ Sbjct: 728 RVVLECKVNPPRAQVKWLQGGREIFPSAKYQICNEDGFHKLIINDVAPEDEDMYTMSTAG 787 Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEK 1241 +C+A L VE +I + L + + V A DA T ++ + W + + E Sbjct: 788 GQCSARLLVEGLAIQISRGLSD-VRVKAPEDACFTCDVSLPLSRPAQWSLNGEPLHNEED 846 Query: 1242 FTLISDVKKRTLIIR 1256 ++ + + LI+R Sbjct: 847 VSIETRGNRHRLILR 861 Score = 92.7 bits (220), Expect = 1e-16 Identities = 69/266 (25%), Positives = 112/266 (42%), Gaps = 10/266 (3%) Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 L V+++ V W +DG + N G R L + D GEY C ES Sbjct: 12 LVVDVSRSDGRVRWFKDGLEVDEDDN-LQVMSEGLRRCLVLPCAVAEDSGEYICDTDSES 70 Query: 1096 CTAEVTVVELPPEIITR---LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152 T +V V+E P +I+ R V G+ + EL++ + +RW KDG E+ + +I Sbjct: 71 ATFDVKVLEPPIKILPRGSSASELNVMAGDPLSIHCELSRNSSDLRWLKDGDEVTPTENI 130 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPA 1210 + G L+ +DAG+Y C VG + V++P ++ PE L+ Sbjct: 131 IMEKLGTMHTLRFLSIQAEDAGQYHCNVGADSRVFTVKVDDPPVSIVGNTGTPEQHLLMT 190 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 D LT E+ V W + + + +++ R L I+ D YTC Sbjct: 191 GDDLVLTCELSRPNFKVRWLRNGEEMVSAGRVKILARGVHRQLTIQNVRPADSGTYTC-- 248 Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYERE 1296 DA T ++ V P++V++ E Sbjct: 249 -DA-GTDQMHTAVYVEAPRVVEFVTE 272 Score = 75.8 bits (178), Expect = 1e-11 Identities = 136/650 (20%), Positives = 246/650 (37%), Gaps = 57/650 (8%) Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 G + +++++ D VRWFKDG E+ +++Q+ +G ++ L + +D+GEY C+ Sbjct: 7 GERVQLVVDVSRSDGRVRWFKDGLEVDEDDNLQVMSEGLRRCLVLPCAVAEDSGEYICDT 66 Query: 1181 GNSKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 + T + V EP I R + V A + E+ + D+ W K + Sbjct: 67 DSESATFDVKVLEPPIKILPRGSSASELNVMAGDPLSIHCELSRNSSDLRWLKDGDEVTP 126 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIV---DYE 1294 TE + TL +D +Y C V D++ T V+V + P IV Sbjct: 127 TENIIMEKLGTMHTLRFLSIQAEDAGQYHCNVGADSRVFT---VKVDDPPVSIVGNTGTP 183 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ + G D+ L + P W+ N + + K LTI+ V D Sbjct: 184 EQHLLMTGDDLVLTCELSR-PNFKVRWLRNGEEMVSAGRVKILARGVHRQLTIQNVRPAD 242 Query: 1355 AGIYKLRLENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 +G Y + H V + +++ + +LE +++S C P+N + Sbjct: 243 SGTYTCDAGTDQMHTAVYVEAPRVVEFVTELQNVTVLEGETASFK-CMVSPDNVD----L 297 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 + + + + + S N + I + + + S + A A E IS A + + Sbjct: 298 RWELNGSPVYSDKRFSTTNNGMCHSLILHSCRLSDSGKITANA--EGLISRAKLRVQEAQ 355 Query: 1473 VIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGV---PQPKVTWYRDGKKLKTAKA 1527 V+ +Q E+ L E E+ + GV P PK T L+ + Sbjct: 356 VLFAQGLQDMEAEEEQDLLLQVQVTREQAEIHWVKQGVVIQPSPKYT-------LQASGC 408 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQKHKV 1586 T+ Y C + +D T C + + + + + +DIK Sbjct: 409 TH----SLTIHGVQASDRGRYSCESLHD----RTECRLNVIPRSISVKKGLKDIKCVEGS 460 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK---Y 1643 ++ V +G+ W+K G +L ND + I + + + + +L SS Sbjct: 461 SVDFTVEMSHDGLVGE---WWKGGVRLTNDDQCTIRSSGRQHFLHLSDLTIPDSSVIAFI 517 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSK---PEG--PVIMREISRESVTIEWKPPLDDGGLEL 1698 T TA + +E L + P EG E+SR+ T+ W D G++L Sbjct: 518 TDTLRTTAQLTVIEHPLTITQPPQDFVVNEGGAATFQCEVSRQDATVTW----DKDGVQL 573 Query: 1699 TKYA-IEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNP 1746 A + R ++++ D Y + N RV+ Q P Sbjct: 574 VPNATCRMYSVGRRRILQLSQCGPSDAGIYTCHMGDINACATLRVLEQEP 623 Score = 41.9 bits (94), Expect = 0.19 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 2/70 (2%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 V+ LR + +G V EC+V PR Q+ W + I PS +Q+ ++D L+I + Sbjct: 715 VKALRDRTALEGHRVVLECKVNP-PRAQVKWLQGGREIFPSAKYQI-CNEDGFHKLIIND 772 Query: 573 VFPEDAGTFT 582 V PED +T Sbjct: 773 VAPEDEDMYT 782 >UniRef50_Q17AF0 Cluster: Novex-3; n=2; Culicidae|Rep: Novex-3 - Aedes aegypti (Yellowfever mosquito) Length = 2679 Score = 170 bits (414), Expect = 3e-40 Identities = 155/601 (25%), Positives = 266/601 (44%), Gaps = 58/601 (9%) Query: 459 QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRP 518 QK + E V + + +E + + Q+ + E K+ + +++ P F+EKL+ Sbjct: 1554 QKRVQEVTDKVAEESVREEQHILESTQQTVAET--KIQEQKIKVKKQKVQPPSFIEKLQS 1611 Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 + V +C++EG P P++ WF ++ + ++ M +D VATL I V P Sbjct: 1612 QICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIVED-VATLEIATVMPYHV 1670 Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638 G +TC AKN AG A S ++V+A E+ G PTF Sbjct: 1671 GVYTCEAKNVAGVALSKANIVVQAK-----PEV-------------------GEAPTFIT 1706 Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI-SVAIESDMHMYCSVLKI 697 K ++ + + C++ IP P + W EEI+ E I +V IE H+ +V K Sbjct: 1707 PLKISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKK- 1765 Query: 698 TNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEK-EP----PQVIEPLKSMIVRQGE 750 K+ YT+ A N+ G+A + ++ T EK +P P+++EPL++ +V+ G Sbjct: 1766 --PKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGS 1823 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 +++ + G P+PT+ W +N+K V + T + +S ++ K G Y + Sbjct: 1824 TLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVH 1883 Query: 809 NSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G A++SA +T+ + +E + A+ P F+ V E L A V P + W+ Sbjct: 1884 NEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWF 1943 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV----TI 923 R I S + EN ++I ++ D G Y C A N AG + A V TI Sbjct: 1944 REGAAIKSSNE-QRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETI 2002 Query: 924 DVEKVT------FVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975 + E+VT F++ + K +G+ +IL CQ + +WYHN++ I ++ Sbjct: 2003 ETEEVTEYISPRFIEPI-KPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQF 2061 Query: 976 IQEGRXX-XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEKD 1032 Q+ D G CI ++ E V E++ + F E+D Sbjct: 2062 QQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRSSEED 2121 Query: 1033 V 1033 + Sbjct: 2122 L 2122 Score = 140 bits (338), Expect = 5e-31 Identities = 126/492 (25%), Positives = 211/492 (42%), Gaps = 40/492 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F +K ++Q + +LL+C++ IP P++ W F + + + I D+ Sbjct: 1602 PPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIVEDV---- 1657 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + L+I V + G YT A N G A IV++ K E P I PLK + Sbjct: 1658 ATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNEDKT 1717 Query: 751 SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDT-H-SITILKPKKVKDEGVYTL 805 ++ QV G P P + W ++ + ++ + T +T H +T+ KPK+ +YT+ Sbjct: 1718 VATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ-NVPILYTI 1776 Query: 806 KAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTRNPV 861 +AEN G A A + ++ T E +P P + Q VK T+ R T P Sbjct: 1777 QAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPK 1836 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P++ W+RN++ + E +T + ++VIT + + SG Y+ + N AG + A V Sbjct: 1837 PTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKK-RSGKYEIIVHNEAGDAKSSASV 1895 Query: 922 TI-------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHR 973 TI + + FV+ L E ++ S+ ST +W+ I + + Sbjct: 1896 TISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNEQ 1955 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKC---IVKDQETSTMLV-VKETI----------PEF 1019 I+ + DVG C V TST V V ETI P F Sbjct: 1956 RIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETEEVTEYISPRF 2015 Query: 1020 IRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 I ++ V + + IL +++ + V W + ++I K+K + L + Sbjct: 2016 IEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQQDSSGRCVLTVSE 2075 Query: 1079 TSVHDEGEYSCI 1090 D GEY+CI Sbjct: 2076 VFPEDTGEYACI 2087 Score = 120 bits (290), Expect = 3e-25 Identities = 105/369 (28%), Positives = 159/369 (43%), Gaps = 38/369 (10%) Query: 497 VFEKPTSEE--QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 V E +EE + ++P F+E ++P DG + CQV P P++ W+ +I ++ Sbjct: 1998 VLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETK 2057 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----APLSD--HG 608 D Q D L + EVFPED G + C+A N G A T + VE P S+ Sbjct: 2058 DKQFQQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRS 2117 Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 SE + A+ +E P + P+ +E LE +++A P+ I WL Sbjct: 2118 SEEDLLTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRWL 2177 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLK 726 EEI+P E + D S+L I ++ GT T A N G A + +V++ Sbjct: 2178 KANEEIIPSEEFQIENFED---GTSILVINDIYPDDSGTITFEAHNALGVATTTTELVVE 2234 Query: 727 IKTGEK-----EPPQVIEPLK------------SMIVRQ-----GESVILSAQVVGNPRP 764 G K E Q +E +K SM ++ GE GNP+P Sbjct: 2235 EHVGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRAMLGEKGFFECHFAGNPKP 2294 Query: 765 TITWCKNNKPVKALP-TKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 I W +N K + A K + HS T I+ P + +D G Y +A + G E+ A + + Sbjct: 2295 DILWYRNGKIIIANERVKICIEEHSATLIIYPVEFEDFGFYKCRAMSDAGSCESYAKL-I 2353 Query: 823 EEPTEENAE 831 E TE E Sbjct: 2354 ESTTETLTE 2362 Score = 117 bits (281), Expect = 4e-24 Identities = 128/479 (26%), Positives = 193/479 (40%), Gaps = 85/479 (17%) Query: 502 TSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 TSE +++ AP FVE L PK + E V+ YP WFR+ A IK S + Q Sbjct: 1900 TSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNE-QRIV 1958 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620 D+N + L+I D G +TC A+N AG +ST + V + Sbjct: 1959 TDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETE------------- 2005 Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 ++ E I P F + K V +G ++L C++ A P P + W + IV E Sbjct: 2006 ------EVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIV--ETK 2057 Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN-------------------------R 715 + D C VL ++ V G Y +A N R Sbjct: 2058 DKQFQQDSSGRC-VLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFR 2116 Query: 716 EGEASLPIVLKIKTGEK--EP----PQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITW 768 E L I T E+ EP PQ+++ L +I+ + + L +V+ P+ I W Sbjct: 2117 SSEEDLLTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRW 2176 Query: 769 CKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 K N+ P + ++ D SI ++ D G T +A N+ G+A T+ + VEE Sbjct: 2177 LKANEEIIPSEEFQIENFEDGTSILVINDIYPDDSGTITFEAHNALGVATTTTELVVEEH 2236 Query: 826 TEENA---------------------EPPLFINRFQE--ITVKEKGTIKLVARVTRNPVP 862 A PP F ++ + EKG + NP P Sbjct: 2237 VGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRAMLGEKGFFE--CHFAGNPKP 2294 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 I WYRN +II +E + + + L+I V+ E D G YKC A + AG A++ Sbjct: 2295 DILWYRNGKIIIANERVKICIEEHSATLIIYPVEFE-DFGFYKCRAMSDAGSCESYAKL 2352 Score = 112 bits (269), Expect = 1e-22 Identities = 134/533 (25%), Positives = 219/533 (41%), Gaps = 76/533 (14%) Query: 432 ETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEK 491 + +E I + E E +YI +T +++ + + K VP Y + N K N Sbjct: 1738 DEEEIIEIEEIETVYIEETG-----HIKLTVKKPKQNVPILYTIQAENKFGKAVGKANLF 1792 Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 I + + EKP E +AP VE L+ + GST+ FEC+ G P+P + WFR + + Sbjct: 1793 IQSITI-EKPKPE--MIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVV 1849 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 ++ + ++ + +VI ++ + +G + + N AG A S+ + + SD SEM Sbjct: 1850 EEEEVTI-VTEEYYSKIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTI----SD-TSEM 1903 Query: 612 TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671 E P F + + V E +LE + + P W +G Sbjct: 1904 D-----------------EAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREG 1946 Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE----ASLPIVLKI 727 I + + + S+L I + K G YT A N G A++ ++ I Sbjct: 1947 AAIKSSNEQRIVTDENK----SILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETI 2002 Query: 728 KTGEKE---PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-D 783 +T E P+ IEP+K V GE +IL+ QV P P + W N + + K Sbjct: 2003 ETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQ 2062 Query: 784 GDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE------------------ 823 D+ +L +V +D G Y A N G A + VE Sbjct: 2063 QDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVEPFEYVPDSEQFRSSEEDL 2122 Query: 824 ------EPTEENAEP----PLFINRFQEITVKEKGTI-KLVARVTRNPVPSITWYRNNEI 872 EE AEP P + + E+ + E+ + KL +V P I W + NE Sbjct: 2123 LTDKSISTLEEYAEPIEYAPQIVKQLPEVIMSEERQLTKLEVKVLAQPKAQIRWLKANEE 2182 Query: 873 ISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 I PSE +NF+ LVI ++ + DSG A N+ G ++ + ++ Sbjct: 2183 IIPSEEFQIENFEDGTSILVINDIYPD-DSGTITFEAHNALGVATTTTELVVE 2234 Score = 111 bits (267), Expect = 2e-22 Identities = 130/517 (25%), Positives = 217/517 (41%), Gaps = 54/517 (10%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784 +K+K + +PP IE L+S I + V+L ++ G P P + W N+ + A P Sbjct: 1593 IKVKKQKVQPPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMN 1652 Query: 785 DTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842 + L+ V GVYT +A+N G+A + A I V+ E E P FI +I Sbjct: 1653 IVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEV-GEAPTFITPL-KI 1710 Query: 843 TVKEKGTIKLV-ARVTRNPVPSITWYRNNEIISPSETITQNFDGE--NIELVITNVDSEI 899 +V E T+ V +V P+P + W+R+ E I E I + E +I+L + + Sbjct: 1711 SVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNV 1770 Query: 900 DSGDYKCVASNSAGKSSHGARV---TIDVEK-------VTFVKHLQKSYETEEGKTVILE 949 Y A N GK+ A + +I +EK V+ LQ + + G T++ E Sbjct: 1771 PI-LYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQ-AQVVKSGSTLVFE 1828 Query: 950 CQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----D 1003 C+ + + KW+ N KE+ + I+ E G + IV D Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888 Query: 1004 QETSTMLVVKET-------IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEI 1055 ++S + + +T P F+ L V E +V ILE ++S T+ W R+G Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAA 1948 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVE------- 1104 IK N+ + L I + + D G Y+C + + TA V V+E Sbjct: 1949 IK-SSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLETIETEEV 2007 Query: 1105 ---LPPEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGK- 1159 + P I ++ +V G K ++ V+W+ + I + Q D Sbjct: 2008 TEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIVETKDKQFQQDSSG 2067 Query: 1160 KQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 + L + + +D GEY+C ++G + C + VE Sbjct: 2068 RCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNVE 2104 Score = 95.1 bits (226), Expect = 2e-17 Identities = 63/220 (28%), Positives = 102/220 (46%), Gaps = 12/220 (5%) Query: 470 PAQYLMDENNYTQYLQKKLNEK-IDKLPVFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTV 527 P +Y+ D + + L +K I L + +P AP V++L + + Sbjct: 2105 PFEYVPDSEQFRSSEEDLLTDKSISTLEEYAEPIE----YAPQIVKQLPEVIMSEERQLT 2160 Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + E +V P+ QI W + I PS++FQ+ +D + LVI +++P+D+GT T A N Sbjct: 2161 KLEVKVLAQPKAQIRWLKANEEIIPSEEFQIENFEDGTSILVINDIYPDDSGTITFEAHN 2220 Query: 588 AAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI--PPTFSKKPKAQYV 645 A G A++TTEL+VE +H + L+ PP+FS + K Sbjct: 2221 ALGVATTTTELVVE----EHVGTKAYRKPEWVQYMEDMKEALQAAYAPPSFSMEIKDSRA 2276 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 G EC P+PDI W G+ I+ +E + + IE Sbjct: 2277 MLGEKGFFECHFAGNPKPDILWYRNGKIIIANERVKICIE 2316 Score = 86.2 bits (204), Expect = 9e-15 Identities = 153/709 (21%), Positives = 285/709 (40%), Gaps = 77/709 (10%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 +E P V+E + ++ E + L + V +P + NK V K + T+ I Sbjct: 1409 EELPHVVETIADIVPE--EVLELIPEEVPLEKPKKRKSRTNKHVVF---KEELSTYEI-- 1461 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQ-EITVKEKGT 849 +P+ VKDE + E E + + + T++ +PTE PL I E ++E+ Sbjct: 1462 -QPEVVKDEEE---EEEEEEEVQQEVSQKTIQLKPTEVTEVKPLPIESIPIEEIMEEQSE 1517 Query: 850 IK--LVARVTRNPVPSI---TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 + + ++ N V + +++ + E ITQ E + V E + Sbjct: 1518 FRKEMAVKIQSNIVKKEKRRVFVDDSQPLPELEIITQKRVQEVTDKVAEESVRE-EQHIL 1576 Query: 905 KCVASNSAGKSSHGARVTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHTV--STK 959 + A ++ + +KV +F++ LQ S E + V+L+C+ + Sbjct: 1577 ESTQQTVAETKIQEQKIKVKKQKVQPPSFIEKLQ-SQICEPNQPVLLQCKIEGIPFPEVR 1635 Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD------QETSTMLVVK 1013 W+ N + + VGV C K+ + + ++ K Sbjct: 1636 WFFNDTVLFANPEYVMNIVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAK 1695 Query: 1014 ETI---PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGE-IIKPKKNKYDF-EK 1067 + P FI L+ ++K VA + +++ V W RD E II+ ++ + + E+ Sbjct: 1696 PEVGEAPTFITPLKISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEE 1755 Query: 1068 RGHIRKLYIRNT--------SVHDEGEYSCILRDESCTAEVTVVELP------PEIITRL 1113 GHI KL ++ ++ E ++ + + + +E P P+I+ L Sbjct: 1756 TGHI-KLTVKKPKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPL 1814 Query: 1114 QNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 Q Q V G+ FE T V+WF++ E+ + + + K+ I Sbjct: 1815 QAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKR 1874 Query: 1173 AGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LVP---ANTDAYLTVEIPDE 1223 +G+Y E G++K +A +T+ + S + P F+ L P A + + + D Sbjct: 1875 SGKYEIIVHNEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDS 1934 Query: 1224 --TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKSTT 1277 T W+++ + I+ + + +++D K LII + D YTC V ST Sbjct: 1935 YPTSTFQWFREGAAIKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTA 1994 Query: 1278 KLKV-------EVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 ++V EV E+ P+ ++ + R+ G + L A P P +W N ++I Sbjct: 1995 TVQVLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPKVQWYHNEQLIV 2054 Query: 1330 KCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + K + DS LT+ +V D G Y N G A + V + Sbjct: 2055 ETKDKQFQQDSSGRCVLTVSEVFPEDTGEYACIASNKLGEAICKTTVNV 2103 Score = 81.8 bits (193), Expect = 2e-13 Identities = 83/412 (20%), Positives = 160/412 (38%), Gaps = 30/412 (7%) Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 K+K + V+ PP ++ + + V L + P P W N ++ + Sbjct: 1594 KVKKQKVQ-PPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMN 1652 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSI 1397 I A+L I V G+Y +N G A + N+ + KP P + S+ Sbjct: 1653 IVEDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISV 1712 Query: 1398 NICWDEPENTGNSTIIYYVV------------EYQEIDTTEWISVKNITKTQTSIQNLKT 1445 N E + T + + E EI+ E + ++ + +++ K Sbjct: 1713 N----EDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ 1768 Query: 1446 NSSYRFRAYAVNEVD--ISDASETTEYYKVIK-ETKIQSPTVEKPLKNITTEPNEDIELT 1502 N + A N+ + A+ + + K + ++ +P + +PL+ + + Sbjct: 1769 NVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFE 1828 Query: 1503 CIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 C F GVP+P V W+R+ K++ + T E Y+ I N+ G+ Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888 Query: 1559 VETSCVVGIQQKPVITISN-----EDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNK 1612 ++S V I + + E + K E ++ AV++ P W++ G Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAA 1948 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 +++ E I T E S++ I+ + YT A N AG+ + T++V + Sbjct: 1949 IKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLE 2000 Score = 63.7 bits (148), Expect = 5e-08 Identities = 66/286 (23%), Positives = 122/286 (42%), Gaps = 22/286 (7%) Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV- 1473 +V + Q + E I+ K + + + S R + + + A + K+ Sbjct: 1539 FVDDSQPLPELEIITQKRVQEVTDKV----AEESVREEQHILESTQQTVAETKIQEQKIK 1594 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATY 1529 +K+ K+Q P+ + L++ EPN+ + L C G+P P+V W+ + L + Sbjct: 1595 VKKQKVQPPSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANPEYVMNIV 1654 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGD 1588 E+ Y C A N G + + +Q KP + + I K V + Sbjct: 1655 EDVATLEIATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNE 1714 Query: 1589 EWLVTAV---IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR--IKELKRSHSSKY 1643 + V V + GIP P+V W+++ ++ +E E+T I+ +K+ K++ Y Sbjct: 1715 DKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNVPILY 1774 Query: 1644 TIEASNTAGTSSVEVTLKV----YDKPSKPE--GPVIMREISRESV 1683 TI+A N G + + L + +KP KPE P I+ + + V Sbjct: 1775 TIQAENKFGKAVGKANLFIQSITIEKP-KPEMIAPKIVEPLQAQVV 1819 Score = 62.5 bits (145), Expect = 1e-07 Identities = 62/272 (22%), Positives = 109/272 (40%), Gaps = 19/272 (6%) Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPL 1488 V NI + +++ + T Y Y +++ + + V + ++ ++PT PL Sbjct: 1650 VMNIVEDVATLE-IATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPL 1708 Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXXXXXXXXX 1542 K E +TC G+P PKV W+RD +++ +T Sbjct: 1709 KISVNEDKTVATVTCQVHGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQ 1768 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ------KPVITISN--EDIK-QKHKVGDEWLVT 1593 Y A N G+ + IQ KP + E ++ Q K G + Sbjct: 1769 NVPILYTIQAENKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFE 1828 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG- 1652 G+P P V W++N ++ ++E I T+E S I I ++ + S KY I N AG Sbjct: 1829 CRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGD 1888 Query: 1653 -TSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 SS VT+ + + + P + ++ + V Sbjct: 1889 AKSSASVTISDTSEMDEAKAPRFVEPLTPKLV 1920 Score = 57.2 bits (132), Expect = 5e-06 Identities = 85/421 (20%), Positives = 157/421 (37%), Gaps = 30/421 (7%) Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 L A + K EV E P I + + + T+ P P W + + I Sbjct: 1685 LSKANIVVQAKPEVGEAPTFITPLKISVNEDK-TVATVTCQVHGIPMPKVRWFRDEEEII 1743 Query: 1330 KCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI----LDKPSP 1383 + + + ++ LT+KK + +Y ++ EN G A + N+ I ++KP P Sbjct: 1744 EIEEIETVYIEETGHIKLTVKKPKQNVPILYTIQAENKFGKAVGKANLFIQSITIEKPKP 1803 Query: 1384 PG-KPNILE------IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 P I+E + S S + T+ ++ + ++ E V + Sbjct: 1804 EMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPTVKWFRNSKEVVEEEEVTIVTEEYYS 1863 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 + I + S ++ NE + +S + + + ++P +PL Sbjct: 1864 KIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTISDTSEMDEAKAPRFVEPLTPKLVAEA 1923 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552 E L + P W+R+G +K++ T EN+ Y C A Sbjct: 1924 EVCILEAVVDSYPTSTFQWFREGAAIKSSNEQRIVTDENKSILIIESFNKRDVGAYTCRA 1983 Query: 1553 FNDHGEVETSCVVG----IQQKPVITISN----EDIKQKHKVGDEWLVTAV-IEGIPPPE 1603 N G V ++ V I+ + V + E IK + E L+ A + P P+ Sbjct: 1984 ENVAGSVTSTATVQVLETIETEEVTEYISPRFIEPIKPTRVMDGEKLILACQVHAAPLPK 2043 Query: 1604 VIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 V WY N + DK++ + + V+ + E+ + +Y ASN G + + T+ Sbjct: 2044 VQWYHNEQLIVETKDKQFQQDSSGR-CVLTVSEVFPEDTGEYACIASNKLGEAICKTTVN 2102 Query: 1662 V 1662 V Sbjct: 2103 V 2103 Score = 47.6 bits (108), Expect = 0.004 Identities = 84/403 (20%), Positives = 154/403 (38%), Gaps = 45/403 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P FI KLQ + +L+ +I +V W + ++ +Y + L Sbjct: 1603 PSFIEKLQSQICEPNQPVLLQCKIEGIPFPEVRWFFNDTVLFANP-EYVMNIVEDVATLE 1661 Query: 1076 IRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEI------ITRLQNQKVNKGNKATF 1126 I + G Y+C ++ + A VV+ PE+ IT L+ AT Sbjct: 1662 IATVMPYHVGVYTCEAKNVAGVALSKANIVVQAKPEVGEAPTFITPLKISVNEDKTVATV 1721 Query: 1127 EIELTKGDAL--VRWFKDGSEI-----------QFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 ++ G + VRWF+D EI + + HI+LT+ KQ + I + Sbjct: 1722 TCQV-HGIPMPKVRWFRDEEEIIEIEEIETVYIEETGHIKLTVKKPKQNVPIL-YTIQAE 1779 Query: 1174 GEYSCEVGNSKC-TAILTVEEPSINFTL-RLPEFILVPA-NTDAYLTVE-----IPDETL 1225 ++ VG + +T+E+P ++ E + + + L E +P T Sbjct: 1780 NKFGKAVGKANLFIQSITIEKPKPEMIAPKIVEPLQAQVVKSGSTLVFECRFTGVPKPT- 1838 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL----DAKSTTKLKV 1281 V W++ + + E+ T++++ ++I K T+ +Y ++ DAKS+ + + Sbjct: 1839 -VKWFRNSKEVVEEEEVTIVTEEYYSKIVITKMTKKRSGKYEIIVHNEAGDAKSSASVTI 1897 Query: 1282 ----EVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 E+ E P+ V+ + L ++P +W IK + Sbjct: 1898 SDTSEMDEAKAPRFVEPLTPKLVAEAEVCILEAVVDSYPTSTFQWFREGAAIKSSNEQRI 1957 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 D + L I+ D G Y R EN G V +L+ Sbjct: 1958 VTDENKSILIIESFNKRDVGAYTCRAENVAGSVTSTATVQVLE 2000 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/84 (29%), Positives = 36/84 (42%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP ++ R G + P+P+ W N KII + K I+ SA+L Sbjct: 2264 PPSFSMEIKDSRAMLGEKGFFECHFAGNPKPDILWYRNGKIIIANERVKICIEEHSATLI 2323 Query: 1347 IKKVENTDAGIYKLRLENNCGHAD 1370 I VE D G YK R ++ G + Sbjct: 2324 IYPVEFEDFGFYKCRAMSDAGSCE 2347 Score = 37.5 bits (83), Expect = 4.0 Identities = 57/250 (22%), Positives = 98/250 (39%), Gaps = 17/250 (6%) Query: 158 LFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPD--DK 215 L + + E +V QP ++ K + EE + P K + E E++ + K Sbjct: 828 LIEEKPAEPIVEVEQPTWRRTKKPKPVEEETEEKKWPTGKRRPLPEEPKEEVTLKPIPKK 887 Query: 216 ETSQTPTSFNKRS-KLTP---IKIERKEMEVSTPQHAETVDG--PQFXXXXXXXXXXXXX 269 E ++ P + + K TP I E KE E++ A+ + P + Sbjct: 888 EKAEEPKPTKEPTIKPTPLPEIPDEPKEEEITIQPPAQEDESHLPPWRRGKKPAQKREIP 947 Query: 270 XETSLVKLPKFQLKSRIKYITSWPPE-----SIKPLISYMGSIKQNGILSRNIKEAAKVK 324 + + +LK K P E S+KP + + + +L + E ++K Sbjct: 948 KPAEPEAMEQIKLKPTPKVKKEIPKEALEEVSLKP-VPKQPEVAEAVVLEPEVSEVKEIK 1006 Query: 325 KQVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITP 384 PK P E LE+P+F +I E + E I++ + E P+E PEQ + Sbjct: 1007 ITKPKEPK-PKREIEPLEKPVFP--EIPEPEPVVLEEIEKVLEVVEKPEEPAPEQPSWRR 1063 Query: 385 RKSSAQKIDE 394 K +DE Sbjct: 1064 EKKPKPVVDE 1073 >UniRef50_UPI00015A4170 Cluster: eEF1A2 binding protein; n=1; Danio rerio|Rep: eEF1A2 binding protein - Danio rerio Length = 928 Score = 170 bits (413), Expect = 4e-40 Identities = 168/768 (21%), Positives = 312/768 (40%), Gaps = 41/768 (5%) Query: 1016 IPEFIRKLQDFEVKEKDVAILEVE--INSETADVVWERDGEII-----KPKKNKYDFEKR 1068 + E + ++ EVK A E + I + + ++GE++ K++ +K Sbjct: 57 VVENVDNMKPIEVKTSGRAEFEFDMRIKDPNSKIYMYKNGEMLDYGAGSDDTCKHNMKKT 116 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPP-EIITRLQNQKVNKGNKATFE 1127 G I N ++D G Y + D + T +E+P E +L++ KV +G A FE Sbjct: 117 GDKYLFSINNLGLNDGGLYQVDVDDVNIIT--TKLEVPDVEFDGKLKDVKVVEGQDAVFE 174 Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGNSKC 1185 + + + W + ++ + +T+ K +L + + +D G Y+ G Sbjct: 175 GVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAGIKSS 234 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI 1245 A L V + ++F L + + A L ++ + ++ WYK + + + + Sbjct: 235 RASLAVNDDKLHFASGLTDKNALRGKP-AELVCKLSTDKINGVWYKDGNKLTSKDGVVIS 293 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD----YEREYRIKR 1301 D L+++ C + D Y + K+ ++V +++ P +D + +K Sbjct: 294 KDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDLDALGKFSNPVIVKA 353 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 G + + + P +W N + K +S + L IK +D G ++R Sbjct: 354 GQSASFKMSFPPQPSLEIKWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIR 413 Query: 1362 LENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 L+N G + ++T+ DKP PP G + E SS + + W+ P++ G S + Y++E Sbjct: 414 LKNPFGSIEALSSLTVQDKPGPPQGPVEVNETTSSVLELKWNPPKDEGGSAVTNYIIEQL 473 Query: 1421 EIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKE 1476 ++ W V +I + +++ Y +R YA N IS+A ET + ++ Sbjct: 474 QVGQNTWQKVGDIPANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKIMAGSLMFP 533 Query: 1477 TKIQSPTVEKPLK---NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 P V K N++ P E I G + + L + K + Sbjct: 534 GPPTQPKVVSAFKNCINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKG-L 592 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVVGIQQKPVITISNEDIKQKHKVG 1587 ++ IA N G E S C KP ED + G Sbjct: 593 KYGVKDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFK-DPEDF-MVVRSG 650 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + + E P P++ W KNG + + I + T + + K S S YTI A Sbjct: 651 NSIRIKINYEAAPQPDIKWLKNGEPVSPWNK--IIHDDGTCTLIVPSSKYSDSGVYTIVA 708 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 N++G +S ++ + D+P +P GPV + ++ V I W P D + Y +E+ Sbjct: 709 KNSSGQASFDI--EFIDEP-RPPGPVELEQLVFGKVIIRWLPSPDHDRDDRLHYMVEEQN 765 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 ++ W +A D + T + EY FR+ A+N +G S+ +S Sbjct: 766 SNSRIWRTIA--DHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811 Score = 159 bits (385), Expect = 1e-36 Identities = 121/464 (26%), Positives = 211/464 (45%), Gaps = 27/464 (5%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P E+ W+KNG++L + + + S ++IK+ RS + + I N G+ + Sbjct: 367 PSLEIKWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSS 426 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 L V DKP P+GPV + E + + ++W PP D+GG +T Y IE+ + N W KV D+ Sbjct: 427 LTVQDKPGPPQGPVEVNETTSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDI 486 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 + + + ++ Y++R+ A+NP G SEALE+E I + +L P Sbjct: 487 PANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKI-MAGSLMFPGPPTQPKVVSAF 545 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX----XXXXXARIQKLSINTT 1834 N + ++W P EK+GG+ I+ Y++E K++ +W ++ +S + Sbjct: 546 KN-CINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSE 604 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEPESN 1892 Y+FR+ A N G P T + + P P +F+V S S+ +K + Sbjct: 605 YEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFKDPEDFMVVRS-GNSIRIKINYEAA- 662 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 P ++ + V W KI+ G+ + + K D ++ I A+N+ G Sbjct: 663 -PQPDIKWLKNGEPV--SPWNKIIHDDGTC-TLIVPSSKYSDSGVYTIVAKNSSG----- 713 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW-GTPEWDGGAPLLGYNIAIRDVTKT 2011 S +E P PP P+E+ + V+ W +P+ D L Y + ++ Sbjct: 714 -QASFDIE-FIDEPRPP-GPVELEQLVFGKVIIRWLPSPDHDRD-DRLHYMVEEQNSNSR 769 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 +W + D + Y RIYA+N++GLS+P +S Sbjct: 770 IWRTI--ADHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811 Score = 124 bits (300), Expect = 2e-26 Identities = 121/551 (21%), Positives = 229/551 (41%), Gaps = 47/551 (8%) Query: 1003 DQETSTMLVVKETIP--EFIRKLQDFEVKEKDVAILEVEINSETADVVW-ERDGEIIKPK 1059 D + ++ K +P EF KL+D +V E A+ E + + + W D + Sbjct: 138 DVDDVNIITTKLEVPDVEFDGKLKDVKVVEGQDAVFEGVFSGPVSQITWCVNDISVEHGD 197 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 K + +L ++N+ D G Y+ I +S A + V + + L ++ Sbjct: 198 KYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAGIKSSRASLAVNDDKLHFASGLTDKNAL 257 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 +G A +L+ W+KDG+++ + + ++ DG KL + +C DAG Y E Sbjct: 258 RGKPAELVCKLSTDKINGVWYKDGNKLTSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFE 317 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEF-----------ILVPANTDAYLTVEIPDE-TLDV 1227 V K A++ V F L LPEF ++V A A + P + +L++ Sbjct: 318 VNGCKTEAMVRV------FLLDLPEFDLDALGKFSNPVIVKAGQSASFKMSFPPQPSLEI 371 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEV 1283 W+K S + D ++ + L I+ C D + L + ++ + L V+ Sbjct: 372 KWFKNGSELLDGGSVKVVKESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSSLTVQD 431 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC---KHTKPSIDS 1340 PP + + + L + + P+ V + II++ ++T + Sbjct: 432 KPGPP-----QGPVEVNETTSSVLELKWNP-PKDEGGSAVTNYIIEQLQVGQNTWQKVGD 485 Query: 1341 KSASLTIKKVENTDAG---IYKLRLENNCGHADV----EMNVTILDKPSPPGKPNILEID 1393 A+ + + G IY++ EN G ++ ++ L P PP +P ++ Sbjct: 486 IPANHLNFRDRSVSLGKRYIYRIYAENPEGISEALETEKIMAGSLMFPGPPTQPKVVSAF 545 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI---SVKN-ITKTQTSIQNLKTNSSY 1449 + IN+ W PE G + I+ Y +E ++ DT +W+ SVK+ I + ++++ S Y Sbjct: 546 KNCINLSWTPPEKDGGNKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEY 605 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 FR A+N + S +E V + P + P + I + + P Sbjct: 606 EFRVIAINSSGAGEPSTPSE--MVCAKNPNMKPHFKDPEDFMVVRSGNSIRIKINYEAAP 663 Query: 1510 QPKVTWYRDGK 1520 QP + W ++G+ Sbjct: 664 QPDIKWLKNGE 674 Score = 124 bits (299), Expect = 3e-26 Identities = 128/483 (26%), Positives = 202/483 (41%), Gaps = 47/483 (9%) Query: 1594 AVIEGI---PPPEVIWYKNGNKLENDKEYNITTKEK--TSVIRIKELKRSHSSKYTIEAS 1648 AV EG+ P ++ W N +E+ +YNIT E T + +K K+ + YT A Sbjct: 171 AVFEGVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKEDNGVYTAIAG 230 Query: 1649 NTAGTSSVEVTL-KVY------DKPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTK 1700 + +S+ V K++ DK + P ++ ++S + + W DG +K Sbjct: 231 IKSSRASLAVNDDKLHFASGLTDKNALRGKPAELVCKLSTDKINGVW---YKDGNKLTSK 287 Query: 1701 YAIEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALE--SE 1756 + + + V + D D Y + E M RV + F +AL S Sbjct: 288 DGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDLDALGKFSN 347 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816 P+++K S+ I WF KNG S ++D G K Sbjct: 348 PVIVKAG------QSASFKMSFPPQPSLEIKWF---KNG-SELLD--------GGSVKVV 389 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 +I+ + T Q +I +N G+ +S +T+ PP P V+E Sbjct: 390 KESNHSRLQIKDCLRSDTGQIQIRLKNPFGSIEALSS---LTVQDKPGPPQGPVE--VNE 444 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936 +TS + LKW P+ GGS +TNYIIE V +W K+ + + ++ Sbjct: 445 TTSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDIPANHLNFRDRSVSLGKRY 504 Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA 1996 I+RI AEN G+S E++ + + P PPT P ++ N + SW PE DGG Sbjct: 505 IYRIYAENPEGISEALETEKI-MAGSLMFPGPPTQP-KVVSAFKNCINLSWTPPEKDGGN 562 Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 +LGY I R W+ + V + LK+ ++D+SE Y R+ A N G EP Sbjct: 563 KILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEYEFRVIAINSSGAGEPST 622 Query: 2055 SDE 2057 E Sbjct: 623 PSE 625 Score = 96.7 bits (230), Expect = 6e-18 Identities = 64/296 (21%), Positives = 129/296 (43%), Gaps = 19/296 (6%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P D E ++ G+ + + ++Y+A PQP+ +W+ N + + K D + +L + Sbjct: 636 PHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSPWN--KIIHDDGTCTLIV 693 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 + +D+G+Y + +N+ G A + + +D+P PPG + ++ + I W + Sbjct: 694 PSSKYSDSGVYTIVAKNSSGQASFD--IEFIDEPRPPGPVELEQLVFGKVIIRWLPSPDH 751 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 ++Y+VE Q ++ W ++ + T ++ Y FR YA N++ +SD S++ Sbjct: 752 DRDDRLHYMVEEQNSNSRIWRTIADHLLCTTYTTTVQPGQEYHFRIYAKNDMGLSDPSDS 811 Query: 1468 TEY----YKVIKETKI-------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 + KV+ + + + P++ PLK + +TC G+P P + WY Sbjct: 812 PTWGVNSNKVLAPSTVPTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWY 871 Query: 1517 RDGKKLKTAKATYENRX----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 +G + + Y YK +A N G E S + ++ Sbjct: 872 HNGICINSDNNYYITNAFGVCSMYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927 Score = 90.6 bits (215), Expect = 4e-16 Identities = 94/366 (25%), Positives = 157/366 (42%), Gaps = 27/366 (7%) Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--- 1661 +WYK+GNKL + I+ T + ++ K S + Y E + + V V L Sbjct: 276 VWYKDGNKLTSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLP 335 Query: 1662 --VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 D K PVI++ S + + PP ++ K E + + + +K ++ Sbjct: 336 EFDLDALGKFSNPVIVKAGQSASFKMSF-PPQPSLEIKWFKNGSELLDGGSVKVVKESNH 394 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 R C++ ++ + R+ +NP G EAL S T D P Sbjct: 395 SRLQIKDCLR--SDTGQIQIRL--KNPFGSIEALSS-----LTVQDKPGPPQGPVEVNET 445 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXX--XXXXXARIQKLSINTTYQ 1836 + + + W P + GGS + +Y +E Q G+ W+ R + +S+ Y Sbjct: 446 TSSVLELKWNPPKDEGGSAVTNYIIEQLQVGQNTWQKVGDIPANHLNFRDRSVSLGKRYI 505 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTL--TPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 +RIYA N G S +KI G + PP+QP+ VVS + + L WT PE +GG Sbjct: 506 YRIYAENPEGIS-EALETEKIMAGSLMFPGPPTQPK--VVS-AFKNCINLSWTPPEKDGG 561 Query: 1895 SPITNYIIEFKTVKGKSWTKIVTVGGSVH--EHCIENIKEKDEIIFRISAENTVGVSLP- 1951 + I Y IE + W + +V + ++ ++++ E E FR+ A N+ G P Sbjct: 562 NKILGYQIEKRKKDTNQWVTLNSVKDPIKGLKYGVKDVSEGSEYEFRVIAINSSGAGEPS 621 Query: 1952 TESQSV 1957 T S+ V Sbjct: 622 TPSEMV 627 Score = 63.7 bits (148), Expect = 5e-08 Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Query: 697 ITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 + +V + E + V+A+N G E S P + P +P M+VR G S+ + Sbjct: 596 VKDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPHFKDPEDFMVVRSGNSIRI 655 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGI 813 P+P I W KN +PV K D + T++ P K D GVYT+ A+NS G Sbjct: 656 KINYEAAPQPDIKWLKNGEPVSPW-NKIIHDDGTCTLIVPSSKYSDSGVYTIVAKNSSGQ 714 Query: 814 AETSAVITVEEP 825 A + ++EP Sbjct: 715 ASFD-IEFIDEP 725 Score = 60.1 bits (139), Expect = 7e-07 Identities = 84/377 (22%), Positives = 148/377 (39%), Gaps = 25/377 (6%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNNEIIS----PSE 877 +E +E A+ ++ + I VK G + + ++P I Y+N E++ + Sbjct: 48 KEKEDEQAKVVENVDNMKPIEVKTSGRAEFEFDMRIKDPNSKIYMYKNGEMLDYGAGSDD 107 Query: 878 TITQNFD--GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 T N G+ I N+ D G Y+ + + ++V V F L Sbjct: 108 TCKHNMKKTGDKYLFSINNLGLN-DGGLYQVDVDDV-----NIITTKLEVPDVEFDGKL- 160 Query: 936 KSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXX- 992 K + EG+ + E S VS W N + D I + E + Sbjct: 161 KDVKVVEGQDAVFEGVFSGPVSQITWCVNDISVEHGDKYNITVSEDKLTHRLVVKNSKKE 220 Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 D GV I + + L V + F L D A L +++++ + VW +D Sbjct: 221 DNGVYTAIAGIKSSRASLAVNDDKLHFASGLTDKNALRGKPAELVCKLSTDKINGVWYKD 280 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV--VELPP--- 1107 G + K+ K G KL ++N D G Y + A V V ++LP Sbjct: 281 GNKL-TSKDGVVISKDGCTHKLVVQNCKDSDAGLYHFEVNGCKTEAMVRVFLLDLPEFDL 339 Query: 1108 EIITRLQNQKVNK-GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 + + + N + K G A+F++ +L ++WFK+GSE+ +++ + +L+I Sbjct: 340 DALGKFSNPVIVKAGQSASFKMSFPPQPSLEIKWFKNGSELLDGGSVKVVKESNHSRLQI 399 Query: 1166 YDCDLDDAGEYSCEVGN 1182 DC D G+ + N Sbjct: 400 KDCLRSDTGQIQIRLKN 416 Score = 55.2 bits (127), Expect = 2e-05 Identities = 79/298 (26%), Positives = 118/298 (39%), Gaps = 31/298 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F V G+ I ++ A P+PDI WL GE + P I I D C+ Sbjct: 636 PHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSPWNKI---IHDD--GTCT 690 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 ++ + + K G YT+VA N G+AS I E PP +E L+ ++ G+ +I Sbjct: 691 LI-VPSSKYSDSGVYTIVAKNSSGQASFDIEF---IDEPRPPGPVE-LEQLVF--GKVII 743 Query: 754 L---SAQVVGNPRPTITWCKNNKPVKALPTKSDG---DTHSITILKPKKV-------KDE 800 S + R + N + T +D T++ T+ ++ D Sbjct: 744 RWLPSPDHDRDDRLHYMVEEQNSNSRIWRTIADHLLCTTYTTTVQPGQEYHFRIYAKNDM 803 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRN 859 G+ + G+ + PT N E P I ++ KG + V Sbjct: 804 GLSDPSDSPTWGVNSNKVLAPSTVPTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGL 863 Query: 860 PVPSITWYRNNEIISPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 P P I WY N I+ IT F + I V E DSG+YK VA NS G++ Sbjct: 864 PSPYIAWYHNGICINSDNNYYITNAFG--VCSMYILRVRPE-DSGEYKVVAVNSLGRA 918 Score = 48.8 bits (111), Expect = 0.002 Identities = 23/76 (30%), Positives = 37/76 (48%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + +T + G+P P + WY NG + +D Y IT + I ++ S +Y + Sbjct: 851 GYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYITNAFGVCSMYILRVRPEDSGEYKVV 910 Query: 1647 ASNTAGTSSVEVTLKV 1662 A N+ G + TLKV Sbjct: 911 AVNSLGRAECSSTLKV 926 Score = 47.6 bits (108), Expect = 0.004 Identities = 28/103 (27%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E ++ +M P F + G++++ + E P+P I W + + P + Sbjct: 625 EMVCAKNPNMKPHFKDPEDFMVVRSGNSIRIKINYEAAPQPDIKWLKNGEPVSP---WNK 681 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 DD TL++ D+G +T VAKN++G AS E I E Sbjct: 682 IIHDDGTCTLIVPSSKYSDSGVYTIVAKNSSGQASFDIEFIDE 724 Score = 46.8 bits (106), Expect = 0.007 Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 1/101 (0%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 PT P + L+ P G C V G P P I W+ I ++ + Sbjct: 828 PTMVNLEKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYI-T 886 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + V ++ I V PED+G + VA N+ G A ++ L V+ Sbjct: 887 NAFGVCSMYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927 Score = 43.2 bits (97), Expect = 0.081 Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 4/96 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+ K +G + C + +P P IAW G I D N + ++ C Sbjct: 836 PPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYI---TNAFGVC 892 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 S + I V+ G Y VVAVN G A LK+K Sbjct: 893 S-MYILRVRPEDSGEYKVVAVNSLGRAECSSTLKVK 927 Score = 42.7 bits (96), Expect = 0.11 Identities = 37/124 (29%), Positives = 56/124 (45%), Gaps = 6/124 (4%) Query: 795 KKVKDEGVYTLK--AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K V + Y + A NS G E S + N +P F + + V+ +I++ Sbjct: 597 KDVSEGSEYEFRVIAINSSGAGEPSTPSEMVCAKNPNMKPH-FKDPEDFMVVRSGNSIRI 655 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 P P I W +N E +SP I + DG +V ++ S DSG Y VA NS+ Sbjct: 656 KINYEAAPQPDIKWLKNGEPVSPWNKIIHD-DGTCTLIVPSSKYS--DSGVYTIVAKNSS 712 Query: 913 GKSS 916 G++S Sbjct: 713 GQAS 716 Score = 38.3 bits (85), Expect = 2.3 Identities = 30/96 (31%), Positives = 46/96 (47%), Gaps = 6/96 (6%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTH 787 ++PP ++ PLK +G ++ V G P P I W N N T + G Sbjct: 834 EKPPSILVPLKLHSPPKGYQCYMTCAVRGLPSPYIAWYHNGICINSDNNYYITNAFG-VC 892 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 S+ IL+ + +D G Y + A NS G AE S+ + V+ Sbjct: 893 SMYILRVRP-EDSGEYKVVAVNSLGRAECSSTLKVK 927 >UniRef50_UPI000065D4F5 Cluster: Homolog of Danio rerio "Novel hemicentin protein; n=1; Takifugu rubripes|Rep: Homolog of Danio rerio "Novel hemicentin protein - Takifugu rubripes Length = 2555 Score = 169 bits (410), Expect = 1e-39 Identities = 200/885 (22%), Positives = 343/885 (38%), Gaps = 67/885 (7%) Query: 521 TPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP-EDA 578 TP GS+V C+ G P P++TW++ + P F+M + + +R+ F Sbjct: 1221 TPQVGSSVTLSCETHGVPEPEVTWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHL 1280 Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638 C + + E I + ++D G T + +PP Sbjct: 1281 RLLECCQISDSRLNCQCGEFIFGSQVAD-GGTYTCKVSNVAGQVDRTFRLTVHVPPVLEG 1339 Query: 639 KP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 ++ GS + L C+ P P I WL G P E+ +++ + S L++ Sbjct: 1340 SLWESLNYTLGSHVSLPCQASGFPVPSITWLKDG---TPIES---SLQWQWSIRGSRLEL 1393 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILS 755 + G YT +A N EG+A L ++ P ++ E + GE + L Sbjct: 1394 GPLALAHGGLYTCLAKNSEGQAQKDYALTVQVS----PTILDSEHPSEVSAPMGEDMTLE 1449 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDT---HSITILKPKKVKDEGVYTLKAENSEG 812 + GNP P ++W K+ V+ ++ G T ++T+L+ D G YT A + G Sbjct: 1450 CRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTPEGSTLTLLR-LSPDDSGTYTCLAVSPAG 1508 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + V P + E + +E+ V + G + L + +P P I+W +N Sbjct: 1509 RQTKIYTLFVLVPPSISGETTV----PREVQVTQDGAVTLECQAVGSPPPQISWLKNGHP 1564 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + S T+ +++ L I+ V DSG Y C+A + AG + V + VE VT V Sbjct: 1565 LLLSSR-TRLLSADSV-LRISPVQLS-DSGVYTCMARSQAGLAELSYDVQVQVEPVTIV- 1620 Query: 933 HLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 +G V L C+ + W + + +S HR ++ +G+ Sbjct: 1621 ---------QGSLVTLSCEARGVPPPTLTWLKDGQPLS--LHRNLLLDGQETRLQLPDVG 1669 Query: 991 XXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI---LEVEINS---ET 1044 D G+ C+ +Q S+ T+ E + +E +A+ LE+E ++ Sbjct: 1670 PSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVT 1101 + W +DG P + + ++ GH + I V D G Y+C+ L E Sbjct: 1730 PTLTWLKDGH---PLERRDIVQEDGHF--VRISKVQVEDAGLYTCLASSLAGEDGKNHWI 1784 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIE-LTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158 V++PP ++ + + V +E L D + W+KD ++Q +Q G Sbjct: 1785 RVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGG 1844 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 Q L+I + +D+G YSC V N + TVE + DA L Sbjct: 1845 --QYLEIQEVKPEDSGLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVTTHIGQDALL 1902 Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 E+ +E+ VTW K I ++TL+S+ +L I D Y C + + Sbjct: 1903 PCEVEEESHATVTWRKDGFPITQDNRYTLLSE---GSLRIHGVQLSDAGRYYCTVSNQAG 1959 Query: 1276 TTKLKVEVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + VE+ F P I + G L + P P W N + + + Sbjct: 1960 SDHRGVELRVFVGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLS 2019 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 S SL + N D G ++ N G + V + D Sbjct: 2020 GAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAGEERRVIEVILQD 2064 Score = 153 bits (371), Expect = 5e-35 Identities = 208/911 (22%), Positives = 349/911 (38%), Gaps = 85/911 (9%) Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 +V D G YT K N G + + +TV P P L + ++ + + L + Sbjct: 1305 QVADGGTYTCKVSNVAGQVDRTFRLTVHVP------PVLEGSLWESLNYTLGSHVSLPCQ 1358 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 + PVPSITW ++ I S + G +EL + G Y C+A NS G++ Sbjct: 1359 ASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLAL---AHGGLYTCLAKNSEGQA 1415 Query: 916 SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHR 973 +T+ V G+ + LEC+ + T W + + G D R Sbjct: 1416 QKDYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSR 1475 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIV-----KDQETSTMLV-VKETIPEFIRKLQDFE 1027 I D G C+ + + T+ V V +I ++ + Sbjct: 1476 HIGVTPEGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQ 1535 Query: 1028 VKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 V + LE + + S + W ++G + +R I + D G Sbjct: 1536 VTQDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTRLLSADSVLR---ISPVQLSDSGV 1592 Query: 1087 YSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE 1145 Y+C+ R ++ AE++ V++ E +T +Q V +A T + W KDG Sbjct: 1593 YTCMARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGVPPPT-----LTWLKDGQP 1647 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLR 1201 + S H L +DG++ +L++ D DAG YSC + G+S T LTV EP Sbjct: 1648 L--SLHRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSS 1705 Query: 1202 LPEFILVPANTDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 PE + + N+ L +P TL TW K +E + I + I K Sbjct: 1706 SPEELFIAVNSPLELECSATGVPPPTL--TWLKDGHPLERRD----IVQEDGHFVRISKV 1759 Query: 1259 TEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFP 1315 +D YTC+ A K V+ PP ++ D R + +TL + P Sbjct: 1760 QVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDP 1819 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P+ EW + ++ + + L I++V+ D+G+Y + N G + + V Sbjct: 1820 APDIEWYKDEVKVQLGGRVQQLAGGQY--LEIQEVKPEDSGLYSCVVTNMAGSSSLFFTV 1877 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 IL P I+ SS + + G ++ VE + T W Sbjct: 1878 EIL-------LPPIIRESSSEVTT------HIGQDALLPCEVEEESHATVTWRK-DGFPI 1923 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVD---ISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 TQ + L + S R +++ + +++ ++ ++ P++ N+T Sbjct: 1924 TQDNRYTLLSEGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVGPSISPGPFNVT 1983 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----XXXXXXXXXY 1548 L+C G+P PKV+W R+G L ++ + R + Sbjct: 1984 VTSGIRAVLSCETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEGYF 2043 Query: 1549 KCIAFNDHGEVETSCVVGIQ--QKPVITISNEDIKQKHKVGDEWLVTAV----------I 1596 +C A N+ GE V +Q Q V + + D VTAV + Sbjct: 2044 ECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIE-DDVTAVTAVKLAPAVLPCHV 2102 Query: 1597 EGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 G P P V W K G KL + Y + T ++ I + SH+ +YT A N+AG + Sbjct: 2103 HGRPQPTVFWTKGGAKLSSRGGTYRVL---PTGLLEITSVLPSHAGRYTCSARNSAGVAH 2159 Query: 1656 VEVTLKVYDKP 1666 V+L V + P Sbjct: 2160 KHVSLSVQESP 2170 Score = 151 bits (365), Expect = 3e-34 Identities = 247/1186 (20%), Positives = 439/1186 (37%), Gaps = 96/1186 (8%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G T C V+ YP P+ITW R I+ + L + EDAG + Sbjct: 1129 EGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPGGQ---MLQLPRARLEDAGQYV 1185 Query: 583 CVAKNAAGFASSTTELIVEA-----PLSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTF 636 C A N+AG + L V P D S++ G+P P Sbjct: 1186 CTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCET---HGVPEPEV 1242 Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 + + + ++ + I + F + E ++ +S ++ C Sbjct: 1243 TWYKNGLQLAPRNGFEMDRYQLEIVGVQVRKTFDVTHLRLLECCQIS-DSRLNCQCGEF- 1300 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILS 755 I + GTYT N G+ L + PP + L +S+ G V L Sbjct: 1301 IFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHV----PPVLEGSLWESLNYTLGSHVSLP 1356 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 Q G P P+ITW K+ P+++ S L P + G+YT A+NSEG A+ Sbjct: 1357 CQASGFPVPSITWLKDGTPIESSLQWQWSIRGSRLELGPLALAHGGLYTCLAKNSEGQAQ 1416 Query: 816 TSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 +TV+ PT ++E P E++ + L R NP P ++W ++ + Sbjct: 1417 KDYALTVQVSPTILDSEHP------SEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVE 1470 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KVTFVKH 933 S++ E L + + + DSG Y C+A + AG+ + + + V ++ Sbjct: 1471 GSDSRHIGVTPEGSTLTLLRLSPD-DSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETT 1529 Query: 934 LQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 + + + + V LECQ S W N + ++ Sbjct: 1530 VPREVQVTQDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTRLLSAD--SVLRISPVQL 1587 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWE 1050 D GV C+ + Q L + +++ + + + L E + W Sbjct: 1588 SDSGVYTCMARSQAGLAELSYDVQV-----QVEPVTIVQGSLVTLSCEARGVPPPTLTWL 1642 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELP 1106 +DG+ + +N G +L + + D G YSC+ +++ T +TV+E P Sbjct: 1643 KDGQPLSLHRNLL---LDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLE-P 1698 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 P++ +++ + E+E + + W KDG ++ + +Q DG + Sbjct: 1699 PKMTGSSSPEELFIAVNSPLELECSATGVPPPTLTWLKDGHPLERRDIVQE--DG--HFV 1754 Query: 1164 KIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 +I ++DAG Y+C G + V+ P + VP N +LT+E Sbjct: 1755 RISKVQVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVN--GHLTLE 1812 Query: 1220 I---PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 D D+ WYK + ++ + ++ + L I++ +D Y+CV+ + + Sbjct: 1813 CLADSDPAPDIEWYKDEVKVQLGGRVQQLAG--GQYLEIQEVKPEDSGLYSCVVTNMAGS 1870 Query: 1277 TKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHT 1334 + L V + PP I + E G D L + + W + I + ++T Sbjct: 1871 SSLFFTVEILLPPIIRESSSEVTTHIGQDALLPCEVEEESHATVTWRKDGFPITQDNRYT 1930 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEI 1392 S SL I V+ +DAG Y + N G H VE+ V + SP G N+ Sbjct: 1931 LLS----EGSLRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVGPSISP-GPFNVTVT 1985 Query: 1393 DS-SSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 ++ C E TG S + + +D ++ + + + + +N Sbjct: 1986 SGIRAVLSC----ETTGIPSPKVSWKRNGTPLDVSQLSGAFRLLSSGSLVLLSPSNEDEG 2041 Query: 1451 -FRAYAVNEVDISDASETTEYYKVIKETKI-------QSPTVEKPLKNITTEPNEDIELT 1502 F AVNE + E +T + P++E + +T L Sbjct: 2042 YFECTAVNEA--GEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLP 2099 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 C G PQP V W + G KL + TY Y C A N G Sbjct: 2100 CHVHGRPQPTVFWTKGGAKLSSRGGTYRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAH 2159 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + +Q+ P I E+++ G ++ +G P P + W + G + + Sbjct: 2160 KHVSLSVQESPEIRPMAEEVQVVLHHGT--VLPCEAQGFPRPSISWQREGVPIATGHRLS 2217 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + ++ + + Y A N AG + + L ++ P Sbjct: 2218 LLS---NGALKFSRVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPP 2260 Score = 136 bits (330), Expect = 5e-30 Identities = 171/743 (23%), Positives = 297/743 (39%), Gaps = 86/743 (11%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C G P P ITW + P +Y + N L I V PE AG F+C A+N+AG Sbjct: 548 CDAFGIPSPTITWSKDG---HPVDTPGVYLQNGN-RMLRIYRVQPEHAGRFSCTAQNSAG 603 Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 A ++V+ H + + T S V G + Sbjct: 604 EARREYSIVVQGK---HIKQPPLTTRTL----------------TMSVSNAELTVALGQE 644 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + +C++ P P + W GE + D + V D VLK+ V+ +G Y Sbjct: 645 VEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQ----VLKVKAVRLRDQGIYQC 700 Query: 711 VAVNREGEASLPIVLKIKTGE-----KEPPQVIEPLKS--MIVRQGESVILSAQVVGNPR 763 +A N G L ++ PP + P ++ + V G S +LS V G+P Sbjct: 701 LASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPT 760 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P+ITW K+N+P+ + P + L + G+YT +A N G A + V Sbjct: 761 PSITWLKDNQPIVSSPQLTYTRGGQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVL 820 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P + + P+F E V+ G++ L P P I W+++ ++++ S + Sbjct: 821 VPPQIEGDSPVF--GTHEEKVRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGS--VHTGI 876 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF-VKHLQKSY---- 938 L+I N + G Y CV +NSAG+ VTI V V V + + ++ Sbjct: 877 QELGHSLLIENT-MLVHEGQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGH 935 Query: 939 ------ETEE------GKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXX 984 +T E G V L C+++ K W+ + +++ D ++ G+ Sbjct: 936 EGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLLSGDGVVLLPGGQ--VL 993 Query: 985 XXXXXXXXDVGVIKC-IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D G C V + M + +F +++ +L ++ + Sbjct: 994 QIARVRKDDAGRYTCQAVNEAGEDHMHFELHILEQF---MEEIAAVVNSTVVLHCDVTGQ 1050 Query: 1044 -TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--- 1099 T V W RDG+ ++ ++ K G +L + + V D Y C+ ++ T E Sbjct: 1051 PTPAVSWLRDGQPVQ-LDPQHQISKDG--TQLQLLSVQVSDMAGYLCVAENKVGTVEKLF 1107 Query: 1100 VTVVELPPEIITRLQNQ-KVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTID 1157 +++PP I ++ + V +G+ A+ ++ + W +DG + F + + Sbjct: 1108 SLTIQVPPRISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPG 1167 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP-AN 1211 G Q L++ L+DAG+Y C NS K + P++ L ++ P Sbjct: 1168 G--QMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVG 1225 Query: 1212 TDAYLTVE---IPDETLDVTWYK 1231 + L+ E +P+ +VTWYK Sbjct: 1226 SSVTLSCETHGVPEP--EVTWYK 1246 Score = 125 bits (302), Expect = 1e-26 Identities = 247/1225 (20%), Positives = 450/1225 (36%), Gaps = 156/1225 (12%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V+F+CQV G P P++ W R ++ D + + +D L ++ V D G + C Sbjct: 642 GQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDG-QVLKVKAVRLRDQGIYQC 700 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A N AG L V+ T+ PPT + Sbjct: 701 LASNNAGTQMRQFRLTVQV--------RTIVVVCLS-------------PPTIKGPSETS 739 Query: 644 YVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 V G LL C + P P I WL + IV ++ L++ +V+ Sbjct: 740 EVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGG------QALRLGSVQ 793 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVG 760 G YT A N G A L + + E + VR S+ LS G Sbjct: 794 GDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKG 853 Query: 761 NPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P P I W K+ + + ++ T HS+ +++ + EG YT NS G + Sbjct: 854 FPEPKIQWFKDGQLLTGSVHTGIQELGHSL-LIENTMLVHEGQYTCVVTNSAGEDKRDFH 912 Query: 820 ITVEEP------TEENAEPPLFINRFQEITVKEKGTIKLVARVTRN------PVPSITWY 867 +T++ P T A L E EK + L V+ + P P ++W+ Sbjct: 913 VTIQVPPVFHRVTNREAAWGLGHEGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWH 972 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ + + + + G+ +++ D D+G Y C A N AG+ + I Sbjct: 973 KDGQKLLSGDGVVLLPGGQVLQIARVRKD---DAGRYTCQAVNEAGEDHMHFELHI---- 1025 Query: 928 VTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 ++ + TV+L C + T + W + + + +I ++G Sbjct: 1026 ---LEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDG--TQLQ 1080 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKL-QDFEVKEKDVAILEVEIN 1041 D+ C+ +++ + + TI P + ++ V E A L ++ Sbjct: 1081 LLSVQVSDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIEGHTASLLCDVQ 1140 Query: 1042 S-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + ++ W RDG+I+ + + L + + D G+Y C + + + Sbjct: 1141 AYPPPEITWTRDGQILAFGTGVHILPGG---QMLQLPRARLEDAGQYVCTATNSAGQDQK 1197 Query: 1101 TV---VELPPEIITRLQNQK----VNKGNKATFEIELTKG--DALVRWFKDGSEIQFSN- 1150 ++ V + P + RL G+ T E T G + V W+K+G ++ N Sbjct: 1198 SILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCE-THGVPEPEVTWYKNGLQLAPRNG 1256 Query: 1151 ----HIQLTIDGKKQK-------LKIYDC-------------------DLDDAGEYSCEV 1180 QL I G + + L++ +C + D G Y+C+V Sbjct: 1257 FEMDRYQLEIVGVQVRKTFDVTHLRLLECCQISDSRLNCQCGEFIFGSQVADGGTYTCKV 1316 Query: 1181 ----GNSKCTAILTVEEP---------SINFTLRLPEFILVPANTDAYLTVEIPDETLDV 1227 G T LTV P S+N+T L + +P + +P + Sbjct: 1317 SNVAGQVDRTFRLTVHVPPVLEGSLWESLNYT--LGSHVSLPCQASGF---PVP----SI 1367 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEF 1286 TW K + IE + ++ ++ L + YTC+ +++ + + V+ Sbjct: 1368 TWLKDGTPIESSLQWQW--SIRGSRLELGPLALAHGGLYTCLAKNSEGQAQKDYALTVQV 1425 Query: 1287 PPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P I+D E E G D+TL P P+ W+ + ++ + + ++ Sbjct: 1426 SPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHIGVTPEGST 1485 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 LT+ ++ D+G Y + G + +L PS G+ + + + D Sbjct: 1486 LTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTV----PREVQVTQD-- 1539 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 G T+ V W+ + + + L +S R ++ V +SD+ Sbjct: 1540 ---GAVTLECQAVG-SPPPQISWLKNGHPLLLSSRTRLLSADSVLR-----ISPVQLSDS 1590 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 T + S V+ ++ +T + L+C GVP P +TW +DG+ L Sbjct: 1591 GVYTCMARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGVPPPTLTWLKDGQPLSL 1650 Query: 1525 AKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582 + Y C+A N G + + + + P +T S+ + Sbjct: 1651 HRNLLLDGQETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEEL 1710 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 V + G+PPP + W K+G+ LE +E +RI +++ + Sbjct: 1711 FIAVNSPLELECSATGVPPPTLTWLKDGHPLER----RDIVQEDGHFVRISKVQVEDAGL 1766 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS 1667 YT AS+ AG ++V P+ Sbjct: 1767 YTCLASSLAGEDGKNHWIRVQVPPT 1791 Score = 121 bits (291), Expect = 3e-25 Identities = 171/778 (21%), Positives = 302/778 (38%), Gaps = 86/778 (11%) Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P P I W G EI P+++ ++ D L I G +T VA N G Sbjct: 461 PRPKIRWFRNGLEIHPEQS-DFSVGED-----GALVIRAASASHSGDFTCVATNEAGSVE 514 Query: 721 LPIVLKIKTGEKEPPQV---IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 LK+ PP++ +PL ++ V + + L G P PTITW K+ PV Sbjct: 515 RKTRLKVNV----PPEIQDDTQPL-NLTVTLKQPLTLGCDAFGIPSPTITWSKDGHPVDT 569 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 + I + + + G ++ A+NS G A I V+ + +PPL Sbjct: 570 PGVYLQNGNRMLRIYRVQP-EHAGRFSCTAQNSAGEARREYSIVVQG--KHIKQPPLTTR 626 Query: 838 RFQ------EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 E+TV ++ +V P P + W R+ E++S F + L Sbjct: 627 TLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHEDGQVLK 686 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV----KHLQKSYETEE----- 942 + V D G Y+C+ASN+AG R+T+ V + V ++ ET E Sbjct: 687 VKAVRLR-DQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSEVSVVL 745 Query: 943 GKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G + +L C + S T S W + + I + G+ G+ C Sbjct: 746 GFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGGQ--ALRLGSVQGDSTGLYTCR 803 Query: 1001 VKD------QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE---TADVVWER 1051 + + S +++V I E K + L + ++ + W + Sbjct: 804 ATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQWFK 863 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPE 1108 DG+++ + ++ GH L I NT + EG+Y+C++ + E +++PP Sbjct: 864 DGQLLTGSVHT-GIQELGH--SLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQVPP- 919 Query: 1109 IITRLQNQKVNKG--------NKATFEIELTKGDAL-------------VRWFKDGSEIQ 1147 + R+ N++ G + ++++ G + + W KDG ++ Sbjct: 920 VFHRVTNREAAWGLGHEGDDEDDTVEKLDVVLGHPVSLSCESNAIPPPKLSWHKDGQKLL 979 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 + + L G Q L+I DDAG Y+C+ N + E ++ + E I Sbjct: 980 SGDGVVLLPGG--QVLQIARVRKDDAGRYTCQAVNEAGEDHMHFE---LHILEQFMEEIA 1034 Query: 1208 VPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 N+ L ++ + T V+W + ++ + + D + L+ D Y Sbjct: 1035 AVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLL--SVQVSDMAGY 1092 Query: 1267 TCVLLDAKSTT-KLKVEVVEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 CV + T KL ++ PP+I + E E + G +LL D QA+P P W + Sbjct: 1093 LCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRD 1152 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 +I+ T I L + + DAG Y N+ G + +++ +P+ Sbjct: 1153 GQIL--AFGTGVHILPGGQMLQLPRARLEDAGQYVCTATNSAGQDQKSILLSVYVRPT 1208 Score = 117 bits (281), Expect = 4e-24 Identities = 183/803 (22%), Positives = 292/803 (36%), Gaps = 98/803 (12%) Query: 630 EGIPPTFSKKPK------AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 + + TFS+ P+ A +V G+D +LEC+ P P + W FKGE V + Sbjct: 164 QSVSLTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRW-FKGEFEVGSTPFA-- 220 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLK 742 D+H L I V++ G YT VA + G A+ ++LK+ K + Sbjct: 221 -GQDVHH--GDLHIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTV 277 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802 M V G V+L + GNP P +TW +N P+ + + ++ D Sbjct: 278 KMAVEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTVLPSGSLRITDVRLIDSKR 337 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 YT AEN G S + ++ L R + T+ L V P P Sbjct: 338 YTCTAENPAGNVSLSYNLHIQAKPRIQPAATLLKARIGQ-------TVTLPCVVQGEPSP 390 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +TW+ N + + D G Y+CVA+NSAG+ + ++ Sbjct: 391 EVTWFHNGLPVGIKNATPLRIHQAKLG----------DQGTYRCVATNSAGQETSEIKLD 440 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 I V + + H + + S +W+ N EI + G Sbjct: 441 ILVRRNSAFAH-----------SFVFVNSGSPRPKIRWFRNGLEIH--PEQSDFSVGEDG 487 Query: 983 XXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQ--DFEVKEKDVAIL 1036 G C+ ++ E T L V PE Q + V K L Sbjct: 488 ALVIRAASASHSGDFTCVATNEAGSVERKTRLKV-NVPPEIQDDTQPLNLTVTLKQPLTL 546 Query: 1037 EVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 + + + W +DG P + + G+ R L I G +SC ++ + Sbjct: 547 GCDAFGIPSPTITWSKDGH---PVDTPGVYLQNGN-RMLRIYRVQPEHAGRFSCTAQNSA 602 Query: 1096 CTA--EVTVVE-----LPPEIITRLQNQKVNK-------GNKATFEIELT-KGDALVRWF 1140 A E ++V P + TR V+ G + F+ ++ K V W Sbjct: 603 GEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWS 662 Query: 1141 KDGSEIQFSN--HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEP 1194 +DG + H++ DG Q LK+ L D G Y C N+ T + LTV+ Sbjct: 663 RDGEVLSRDGDPHVEFHEDG--QVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVR 720 Query: 1195 SINFTLRLPEFILVPANT---------DAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244 +I P I P+ T L+ ++ T +TW K I + + T Sbjct: 721 TIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTY 780 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT-KLKVEVVEFPPKI-----VDYEREYR 1298 + L + D YTC + T K VV PP+I V E + Sbjct: 781 TRG--GQALRLGSVQGDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEK 838 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ +TL + FP+P +W + +++ HT I SL I+ G Y Sbjct: 839 VRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHT--GIQELGHSLLIENTMLVHEGQY 896 Query: 1359 KLRLENNCGHADVEMNVTILDKP 1381 + N+ G + +VTI P Sbjct: 897 TCVVTNSAGEDKRDFHVTIQVPP 919 Score = 112 bits (270), Expect = 9e-23 Identities = 134/624 (21%), Positives = 251/624 (40%), Gaps = 43/624 (6%) Query: 1075 YIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRL-QNQKVNKGNKATFEIEL 1130 +I + V D G Y+C + + + + T V +PP + L ++ G+ + + Sbjct: 1300 FIFGSQVADGGTYTCKVSNVAGQVDRTFRLTVHVPPVLEGSLWESLNYTLGSHVSLPCQA 1359 Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA-- 1187 + + W KDG+ I+ S Q +I G + L++ L G Y+C NS+ A Sbjct: 1360 SGFPVPSITWLKDGTPIESSLQWQWSIRGSR--LELGPLALAHGGLYTCLAKNSEGQAQK 1417 Query: 1188 --ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTL 1244 LTV+ P + P D L + T ++W K +E ++ + Sbjct: 1418 DYALTVQVSPTILDSEHPSEVSAPMGEDMTLECRAAGNPTPHLSWLKDGVTVEGSDSRHI 1477 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI---VDYEREYRIK 1300 + TL + + + DD YTC+ + A TK+ V PP I RE ++ Sbjct: 1478 GVTPEGSTLTLLRLSPDDSGTYTCLAVSPAGRQTKIYTLFVLVPPSISGETTVPREVQVT 1537 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 + VTL P P W+ N + T+ + S + L I V+ +D+G+Y Sbjct: 1538 QDGAVTLECQAVGSPPPQISWLKNGHPLLLSSRTR--LLSADSVLRISPVQLSDSGVYTC 1595 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + G A++ +V + +P + +++ + + + P T + ++ + Q Sbjct: 1596 MARSQAGLAELSYDVQVQVEPVTIVQGSLVTLSCEARGV----PPPT-----LTWLKDGQ 1646 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 + + + +T+ + ++ + + + A N+ S + + K T Sbjct: 1647 PLSLHRNLLLDG-QETRLQLPDVGPSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSS 1705 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540 SP + + N +EL C GVP P +TW +DG L+ E+ Sbjct: 1706 SP------EELFIAVNSPLELECSATGVPPPTLTWLKDGHPLERRDIVQEDGHFVRISKV 1759 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y C+A + GE + + +Q P + S+E V + + + P Sbjct: 1760 QVEDAGLYTCLASSLAGEDGKNHWIRVQVPPTLLGSDEVRTVTVPVNGHLTLECLADSDP 1819 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P++ WYK+ K++ + + I+E+K S Y+ +N AG+SS+ T+ Sbjct: 1820 APDIEWYKDEVKVQLGG--RVQQLAGGQYLEIQEVKPEDSGLYSCVVTNMAGSSSLFFTV 1877 Query: 1661 KVYDKPSKPEGPVIMREISRESVT 1684 ++ P I+RE S E T Sbjct: 1878 EILLPP-------IIRESSSEVTT 1894 Score = 110 bits (264), Expect = 5e-22 Identities = 188/959 (19%), Positives = 346/959 (36%), Gaps = 93/959 (9%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 G +LS +V G+ R +TW + + + A +S S + +++D G Y A Sbjct: 7 GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSLQISGVQIQDAGEYHCVAT 66 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N+ G ++ ++ + P E P + Q I+ V + +P P + W Sbjct: 67 NAHG--DSRIIVWLHVP-----EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSH 119 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 N +++ + + N G L I E D+G+Y C+A+N AG +S V++ + Sbjct: 120 GNMLLTNRQRLNINHYG---VLTIKGALPE-DAGNYTCLATNEAGVASQS--VSLTFSEA 173 Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXX 986 ++ Q++ G +LECQ + +W+ + E+ Q+ Sbjct: 174 PRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAG--QDVHHGDLHI 231 Query: 987 XXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI-----RKLQDFEVKEKDVAILEV 1038 D G C+ T T+++ +P+ I K V+ +L Sbjct: 232 RGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPC 291 Query: 1039 EINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 E + +V W R+G I P + G +R I + + D Y+C + + Sbjct: 292 EAQGNPSPLVTWSRNGHPIPPVTAGFTVLPSGSLR---ITDVRLIDSKRYTCTAENPAGN 348 Query: 1098 AEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHI 1152 ++ ++ P I K G T + +G+ V WF +G + N Sbjct: 349 VSLSYNLHIQAKPRIQPAATLLKARIGQTVTLPC-VVQGEPSPEVTWFHNGLPVGIKN-- 405 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 L+I+ L D G Y C NS A E ++ +R A Sbjct: 406 -------ATPLRIHQAKLGDQGTYRCVATNS---AGQETSEIKLDILVRRNS-----AFA 450 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 +++ V + W++ I + + + L+IR + ++TCV + Sbjct: 451 HSFVFVNSGSPRPKIRWFRNGLEIHPEQSDFSVGE--DGALVIRAASASHSGDFTCVATN 508 Query: 1273 AKSTTKLKVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + + K + V PP+I D + + +TL D P P W SK Sbjct: 509 EAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGCDAFGIPSPTITW---SKDGH 565 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--PSPPGKP 1387 + + + L I +V+ AG + +N+ G A E ++ + K PP Sbjct: 566 PVDTPGVYLQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKHIKQPPLTT 625 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--------TKTQTS 1439 L + S+ + G V + EW + + Sbjct: 626 RTLTMSVSNAEL----TVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPHVEFHED 681 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASET-------TEYYKVIKETKIQSPTVEKP--LKN 1490 Q LK + R R + + S+ + T T + I + PT++ P Sbjct: 682 GQVLKV-KAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSPPTIKGPSETSE 740 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY-ENRXXXXXXXXXXXXXXXY 1548 ++ L+C G P P +TW +D + + + + TY Y Sbjct: 741 VSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQLTYTRGGQALRLGSVQGDSTGLY 800 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPEVI 1605 C A N G + + P I + ++K ++ ++ + +G P P++ Sbjct: 801 TCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFGTHEEKVRMNGSLTLSCMTKGFPEPKIQ 860 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKV 1662 W+K+G L I +E + I+ H +YT +N+AG VT++V Sbjct: 861 WFKDGQLLTGSVHTGI--QELGHSLLIENTMLVHEGQYTCVVTNSAGEDKRDFHVTIQV 917 Score = 106 bits (254), Expect = 8e-21 Identities = 135/567 (23%), Positives = 219/567 (38%), Gaps = 66/567 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+ P+++ G +I C P P + W + + +++ + Sbjct: 84 PSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNIN-------HYG 136 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 VL I G YT +A N G AS + L E P++ +++ V G + Sbjct: 137 VLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFS----EAPRIRVTQQAIHVSVGADAV 192 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L Q G P P + W K V + P H ++ + D G YT A + G Sbjct: 193 LECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHGDLHIRGVQEVDAGRYTCVASSPAGT 252 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVK---EKGT-IKLVARVTRNPVPSITWYRN 869 A + ++ V A P + + TVK E GT + L NP P +TW RN Sbjct: 253 ATGTVILKV------GAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPSPLVTWSRN 306 Query: 870 NEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 I P +T F + L IT+V IDS Y C A N AG S + ++ Sbjct: 307 GHPIPP---VTAGFTVLPSGSLRITDV-RLIDSKRYTCTAENPAGNVS--LSYNLHIQAK 360 Query: 929 TFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 ++ + G+TV L C Q + W+HN + G+ + ++ Sbjct: 361 PRIQPAATLLKARIGQTVTLPCVVQGEPSPEVTWFHNGLPV-GIKNATPLR--------I 411 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D G +C+ + +K I +R+ F + + V S Sbjct: 412 HQAKLGDQGTYRCVATNSAGQETSEIKLDI--LVRRNSAFA-----HSFVFVNSGSPRPK 464 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103 + W R+G I P+++ + + G L IR S G+++C+ +E+ + E V Sbjct: 465 IRWFRNGLEIHPEQSDFSVGEDG---ALVIRAASASHSGDFTCVATNEAGSVERKTRLKV 521 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKG-DAL------VRWFKDGSEIQFSNHIQLTI 1156 +PPEI + Q +N T + LT G DA + W KDG + + + Sbjct: 522 NVPPEI--QDDTQPLNL--TVTLKQPLTLGCDAFGIPSPTITWSKDGHPVDTPG---VYL 574 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 + L+IY + AG +SC NS Sbjct: 575 QNGNRMLRIYRVQPEHAGRFSCTAQNS 601 Score = 101 bits (241), Expect = 3e-19 Identities = 101/389 (25%), Positives = 154/389 (39%), Gaps = 41/389 (10%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+ +G+PRP I+W R+ I + + L V DAGT+ C+AKN AG Sbjct: 2191 CEAQGFPRPSISWQREGVPIATGHRLSLLSN----GALKFSRVTLGDAGTYQCLAKNEAG 2246 Query: 591 FASSTTELIVEAP--LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 A T+L++ P +S +E++V +G P PK + G Sbjct: 2247 AAVGQTKLVLHVPPLISPAQTELSVIQGFQALLSCAA----QGSPD-----PKISWEKNG 2297 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN----VKKFQ 704 S + IP L GE I+ + + I + + + + + Sbjct: 2298 SPV------PNIPGKYTV-LRSGELIIERAEVCLLILAALRLEAHQNPLNQFWFLTQPAD 2350 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G +T VA N G A L I P E + + +G+S+ LS G P P Sbjct: 2351 AGLFTCVATNAAGSARQDRRLSINMR----PAFKELPGDVTLNKGQSLALSCHAQGTPSP 2406 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 I+W NN P + G S I++ D G Y AEN G T + + V E Sbjct: 2407 VISWTVNNSPRQGAAVDEAG--RSSLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVRE 2464 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P P L + TV + + L + +P P + W R+ + S I + Sbjct: 2465 P------PVLKGDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLN 2518 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAG 913 G LVI +V+ G+Y+C+A N AG Sbjct: 2519 G---SLVIYSVNVNTHEGEYQCLAENEAG 2544 Score = 95.5 bits (227), Expect = 1e-17 Identities = 137/603 (22%), Positives = 239/603 (39%), Gaps = 63/603 (10%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G C+ G P P+++W R + SQ + + +LV+ ED G F C Sbjct: 1987 GIRAVLSCETTGIPSPKVSWKRNGTPLDVSQ-LSGAFRLLSSGSLVLLSPSNEDEGYFEC 2045 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A N AG ++E L D +++ V + +PP+ A Sbjct: 2046 TAVNEAG----EERRVIEVILQDGQTDVCVF-------------MFCSVPPSIEDDVTAV 2088 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 + + +L C + P+P + W G ++ + + + L+IT+V Sbjct: 2089 TAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLSSRGGTYRVLPTGL------LEITSVLPS 2142 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G YT A N G A + L ++ E P++ + + V +L + G PR Sbjct: 2143 HAGRYTCSARNSAGVAHKHVSLSVQ----ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPR 2198 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA--ETSAVIT 821 P+I+W + P+ S ++ + + D G Y A+N G A +T V+ Sbjct: 2199 PSISWQREGVPIATGHRLSLLSNGALKFSRVT-LGDAGTYQCLAKNEAGAAVGQTKLVLH 2257 Query: 822 VEEPTEENAEPPL-FINRFQEI-TVKEKGTI--KLVARVTRNPVPSI----TWYRNNE-I 872 V P A+ L I FQ + + +G+ K+ +PVP+I T R+ E I Sbjct: 2258 VP-PLISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKNGSPVPNIPGKYTVLRSGELI 2316 Query: 873 ISPSETITQNFDGENIELVITNVDS------EIDSGDYKCVASNSAGKSSHGARVTIDVE 926 I +E +E ++ D+G + CVA+N+AG + R++I++ Sbjct: 2317 IERAEVCLLILAALRLEAHQNPLNQFWFLTQPADAGLFTCVATNAAGSARQDRRLSINMR 2376 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXX 984 K L +G+++ L C T S W N G + E Sbjct: 2377 PA--FKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNSPRQG----AAVDEAGRSSL 2430 Query: 985 XXXXXXXXDVGVIKCIVKDQETS--TMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEI 1040 D G C+ +++ S T+ V+ P ++ V + IL+ I Sbjct: 2431 IIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCPI 2490 Query: 1041 NSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + + + V+ W RDG + + ++ G + +Y N + H EGEY C+ +E+ TAE Sbjct: 2491 HGDPSPVLQWLRDGNALL-RSHRIQALLNGSL-VIYSVNVNTH-EGEYQCLAENEAGTAE 2547 Query: 1100 VTV 1102 T+ Sbjct: 2548 RTI 2550 Score = 87.8 bits (208), Expect = 3e-15 Identities = 168/792 (21%), Positives = 294/792 (37%), Gaps = 98/792 (12%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK--KPKAQYVDEGSDILLEC 655 L++ A + H + T + +PP +P V + L C Sbjct: 489 LVIRAASASHSGDFTCVATNEAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGC 548 Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 IP P I W G P + V +++ M L+I V+ G ++ A N Sbjct: 549 DAFGIPSPTITWSKDGH---PVDTPGVYLQNGNRM----LRIYRVQPEHAGRFSCTAQNS 601 Query: 716 EGEASLPIVLKIKTGE-KEPPQVIEPL------KSMIVRQGESVILSAQVVGNPRPTITW 768 GEA + ++ K+PP L + V G+ V QV G P P + W Sbjct: 602 AGEARREYSIVVQGKHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEW 661 Query: 769 CKNNKPVKALPTKSDGDTH-------SITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 ++ + + DGD H + +K +++D+G+Y A N+ G +T Sbjct: 662 SRDGEVL-----SRDGDPHVEFHEDGQVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLT 716 Query: 822 VEEPT--EENAEPPLF--INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 V+ T PP + E++V + L V +P PSITW ++N+ I S Sbjct: 717 VQVRTIVVVCLSPPTIKGPSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSP 776 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVT-----IDVEKVTFV 931 +T G+ + L DS +G Y C A+N AG + H + V I+ + F Sbjct: 777 QLTYTRGGQALRLGSVQGDS---TGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPVFG 833 Query: 932 KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 H +K ++ L C T K W+ + + ++G H I + G Sbjct: 834 THEEK---VRMNGSLTLSCMTKGFPEPKIQWFKDGQLLTGSVHTGIQELGHSLLIENTML 890 Query: 990 XXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKL--------------QDFEVKEKD 1032 G C+V + ++ V + P F R +D V++ D Sbjct: 891 VHE--GQYTCVVTNSAGEDKRDFHVTIQVPPVFHRVTNREAAWGLGHEGDDEDDTVEKLD 948 Query: 1033 VAI-----LEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 V + L E N+ + W +DG+ + + G + L I D G Sbjct: 949 VVLGHPVSLSCESNAIPPPKLSWHKDGQKLL-SGDGVVLLPGGQV--LQIARVRKDDAGR 1005 Query: 1087 YSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK 1141 Y+C +E+ E+ ++E E I + N V ++T + V W + Sbjct: 1006 YTCQAVNEAGEDHMHFELHILEQFMEEIAAVVNSTV------VLHCDVTGQPTPAVSWLR 1059 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSIN 1197 DG +Q Q++ DG +L++ + D Y C +VG + LT++ P Sbjct: 1060 DGQPVQLDPQHQISKDG--TQLQLLSVQVSDMAGYLCVAENKVGTVEKLFSLTIQVPPRI 1117 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 E ++ +T + L ++TW + ++ ++ + L + + Sbjct: 1118 SGHMEEETSVIEGHTASLLCDVQAYPPPEITWTRDGQILAFGTGVHILPG--GQMLQLPR 1175 Query: 1258 CTEDDQCEYTCVLLDA----KSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 +D +Y C ++ + + L V V P++ + GS VTL + Sbjct: 1176 ARLEDAGQYVCTATNSAGQDQKSILLSVYVRPTMKPRLDAASDLVTPQVGSSVTLSCETH 1235 Query: 1313 AFPQPNDEWIVN 1324 P+P W N Sbjct: 1236 GVPEPEVTWYKN 1247 Score = 85.4 bits (202), Expect = 2e-14 Identities = 148/673 (21%), Positives = 252/673 (37%), Gaps = 78/673 (11%) Query: 1033 VAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 VA+L ++ ++ W R G I + K L I + D GEY C+ Sbjct: 9 VAVLSCKVEGSVRHNLTWYRAGRAIGAHTGR---SKVLPDSSLQISGVQIQDAGEYHCVA 65 Query: 1092 RDESCTAEVTV-VELP--PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 + + + V + +P P ++ Q++ ++G + F + G + F + Sbjct: 66 TNAHGDSRIIVWLHVPEAPSVVIHPQSRVFSRGEEIRFVCSAS-GSPPPQLFWSHGNMLL 124 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLP 1203 +N +L I+ L I +DAG Y+C E G + + LT E P I T Sbjct: 125 TNRQRLNIN-HYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSEAPRIRVT---Q 180 Query: 1204 EFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 + I V DA L + V W+K + + T DV L IR E D Sbjct: 181 QAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAG--QDVHHGDLHIRGVQEVD 238 Query: 1263 QCEYTCVLLDAKST-TKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFPQ 1316 YTCV T T + V PKI+ D + ++ G++V L + Q P Sbjct: 239 AGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPCEAQGNPS 298 Query: 1317 PNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 P W N I T S SL I V D+ Y EN G +V ++ Sbjct: 299 PLVTWSRNGHPIPPV--TAGFTVLPSGSLRITDVRLIDSKRYTCTAENPAG--NVSLSYN 354 Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW------ISV 1430 + + P +P + + G + + VV+ + W + + Sbjct: 355 LHIQAKPRIQPAATLLKA-----------RIGQTVTLPCVVQGEPSPEVTWFHNGLPVGI 403 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 KN T + I K +R A N S ET+E IK + Sbjct: 404 KNATPLR--IHQAKLGDQGTYRCVATN----SAGQETSE----IK-------------LD 440 Query: 1491 ITTEPNEDIELTCIF--GGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXX 1546 I N + +F G P+PK+ W+R+G ++ ++ + Sbjct: 441 ILVRRNSAFAHSFVFVNSGSPRPKIRWFRNGLEIHPEQSDFSVGEDGALVIRAASASHSG 500 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 + C+A N+ G VE + + P I + + + + GIP P + W Sbjct: 501 DFTCVATNEAGSVERKTRLKVNVPPEIQDDTQPLNLTVTLKQPLTLGCDAFGIPSPTITW 560 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K+G+ ++ Y + ++RI ++ H+ +++ A N+AG + E ++ V K Sbjct: 561 SKDGHPVDTPGVY---LQNGNRMLRIYRVQPEHAGRFSCTAQNSAGEARREYSIVVQGKH 617 Query: 1667 SKPEGPVIMREIS 1679 K + P+ R ++ Sbjct: 618 IK-QPPLTTRTLT 629 Score = 74.1 bits (174), Expect = 4e-11 Identities = 76/321 (23%), Positives = 132/321 (41%), Gaps = 26/321 (8%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G+ +L C++ ++ W G I S + S L+I+ V+ G Sbjct: 7 GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPD------SSLQISGVQIQDAGE 60 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y VA N G++ + + L + E P V+ +S + +GE + G+P P + Sbjct: 61 YHCVATNAHGDSRIIVWLHVP----EAPSVVIHPQSRVFSRGEEIRFVCSASGSPPPQLF 116 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 W N + + + + + + +K +D G YT A N G+A S +T E Sbjct: 117 WSHGNM-LLTNRQRLNINHYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSE--- 172 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 P + + + Q I V L + T P P + W++ + + Q D + Sbjct: 173 ---APRIRVTQ-QAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQ--DVHH 226 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKVTFVKHLQKSYE--TEEGK 944 +L I V E+D+G Y CVAS+ AG ++ + + + K+ V K+ + E G Sbjct: 227 GDLHIRGV-QEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGT 285 Query: 945 TVILECQTSHTVS--TKWYHN 963 V+L C+ S W N Sbjct: 286 EVVLPCEAQGNPSPLVTWSRN 306 Score = 71.3 bits (167), Expect = 3e-10 Identities = 82/349 (23%), Positives = 139/349 (39%), Gaps = 40/349 (11%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P+ S P V G +L C IP P ++W G + ++S + + Sbjct: 1971 VGPSISPGPFNVTVTSGIRAVLSCETTGIPSPKVSWKRNGTPL----DVSQLSGAFRLLS 2026 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE---------PPQVIEPLK 742 L + + EG + AVN GE I + ++ G+ + PP + + + Sbjct: 2027 SGSLVLLSPSNEDEGYFECTAVNEAGEERRVIEVILQDGQTDVCVFMFCSVPPSIEDDVT 2086 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT---ILKPKKV-- 797 ++ + +L V G P+PT+ W K + S G T+ + +L+ V Sbjct: 2087 AVTAVKLAPAVLPCHVHGRPQPTVFWTKGGAKLS-----SRGGTYRVLPTGLLEITSVLP 2141 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARV 856 G YT A NS G+A ++V+E E P+ +E+ V GT+ L Sbjct: 2142 SHAGRYTCSARNSAGVAHKHVSLSVQESPEIR---PMA----EEVQVVLHHGTV-LPCEA 2193 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P PSI+W R I+ ++ +G L + V D+G Y+C+A N AG + Sbjct: 2194 QGFPRPSISWQREGVPIATGHRLSLLSNGA---LKFSRVTLG-DAGTYQCLAKNEAGAAV 2249 Query: 917 HGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHN 963 ++ + V + + Q +G +L C Q S W N Sbjct: 2250 GQTKLVLHVPPL--ISPAQTELSVIQGFQALLSCAAQGSPDPKISWEKN 2296 Score = 64.5 bits (150), Expect = 3e-08 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 3/173 (1%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 ++T + + L+C G P P ++W + + A R Y Sbjct: 2385 DVTLNKGQSLALSCHAQGTPSPVISWTVNNSPRQGAAVDEAGRSSLIIENVTTSDAGTYV 2444 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 C+A N G V T V +++ PV+ + + Q G ++ I G P P + W ++ Sbjct: 2445 CVAENRVGSVRTLSFVRVREPPVLK-GDAHMSQTVIQGSSTILDCPIHGDPSPVLQWLRD 2503 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 GN L + + I S++ +H +Y A N AGT+ + LKV Sbjct: 2504 GNALL--RSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAGTAERTIALKV 2554 Score = 60.9 bits (141), Expect = 4e-07 Identities = 43/187 (22%), Positives = 75/187 (40%), Gaps = 7/187 (3%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXX 1545 ++ +T N + L C+ P P + WY+D K++ + Sbjct: 1798 VRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQYLEIQEVKPEDS 1857 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y C+ N G V I P+I S+ ++ +G + L+ +E V Sbjct: 1858 GLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVTTH--IGQDALLPCEVEEESHATVT 1915 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W K+G + D Y + ++ +RI ++ S + +Y SN AG+ V L+V+ Sbjct: 1916 WRKDGFPITQDNRYTLLSEGS---LRIHGVQLSDAGRYYCTVSNQAGSDHRGVELRVFVG 1972 Query: 1666 PSKPEGP 1672 PS GP Sbjct: 1973 PSISPGP 1979 Score = 60.9 bits (141), Expect = 4e-07 Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 13/191 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + P +++G + L C P P I+W P + +V E+ S Sbjct: 2377 PAFKELPGDVTLNKGQSLALSCHAQGTPSPVISWTVNNS---PRQGAAVD-EAGR----S 2428 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESV 752 L I NV GTY VA NR G +++ +EPP + + S V QG S Sbjct: 2429 SLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRV----REPPVLKGDAHMSQTVIQGSST 2484 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 IL + G+P P + W ++ + S+ I EG Y AEN G Sbjct: 2485 ILDCPIHGDPSPVLQWLRDGNALLRSHRIQALLNGSLVIYSVNVNTHEGEYQCLAENEAG 2544 Query: 813 IAETSAVITVE 823 AE + + V+ Sbjct: 2545 TAERTIALKVQ 2555 Score = 60.5 bits (140), Expect = 5e-07 Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 6/189 (3%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXX 1541 +E+ ++ I N + L C G P P V+W RDG+ +L ++ Sbjct: 1026 LEQFMEEIAAVVNSTVVLHCDVTGQPTPAVSWLRDGQPVQLDPQHQISKDGTQLQLLSVQ 1085 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+A N G VE + IQ P I+ E+ + G + ++ PP Sbjct: 1086 VSDMAGYLCVAENKVGTVEKLFSLTIQVPPRISGHMEEETSVIE-GHTASLLCDVQAYPP 1144 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 PE+ W ++G L +I + ++++ + + +Y A+N+AG + L Sbjct: 1145 PEITWTRDGQILAFGTGVHILPGGQ--MLQLPRARLEDAGQYVCTATNSAGQDQKSILLS 1202 Query: 1662 VYDKPS-KP 1669 VY +P+ KP Sbjct: 1203 VYVRPTMKP 1211 Score = 59.3 bits (137), Expect = 1e-06 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 7/179 (3%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXX 1547 N+T+ L+C G + +TWYR G+ + T ++ Sbjct: 1 NVTSSVGAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPDSSLQISGVQIQDAGE 60 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y C+A N HG+ + + + P + I + + G+E G PPP++ W Sbjct: 61 YHCVATNAHGDSRIIVWLHVPEAPSVVIHPQ--SRVFSRGEEIRFVCSASGSPPPQLFWS 118 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 L N + NI V+ IK + YT A+N AG +S V+L + P Sbjct: 119 HGNMLLTNRQRLNI---NHYGVLTIKGALPEDAGNYTCLATNEAGVASQSVSLTFSEAP 174 Score = 58.0 bits (134), Expect = 3e-06 Identities = 52/219 (23%), Positives = 92/219 (42%), Gaps = 20/219 (9%) Query: 1472 KVIKETKIQSPTVEKPLKN--ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 K IK+ + + T+ + N +T +++E C G P P+V W RDG+ L + Sbjct: 616 KHIKQPPLTTRTLTMSVSNAELTVALGQEVEFQCQVRGKPPPRVEWSRDGEVLSRDGDPH 675 Query: 1530 ----ENRXXXXXXXXXXXXXXXYKCIAFNDHG----------EVETSCVVGIQQKPVITI 1575 E+ Y+C+A N+ G +V T VV + P I Sbjct: 676 VEFHEDGQVLKVKAVRLRDQGIYQCLASNNAGTQMRQFRLTVQVRTIVVVCLSP-PTIKG 734 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 +E + +G L++ +EG P P + W K+ + + + +T +R+ + Sbjct: 735 PSETSEVSVVLGFSTLLSCDVEGSPTPSITWLKDNQPIVSSPQ--LTYTRGGQALRLGSV 792 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPV 1673 + + YT A+N AGT+ +L V P + + PV Sbjct: 793 QGDSTGLYTCRATNPAGTAIKHYSLVVLVPPQIEGDSPV 831 Score = 57.6 bits (133), Expect = 4e-06 Identities = 45/211 (21%), Positives = 86/211 (40%), Gaps = 7/211 (3%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN--RXXXXX 1537 ++P + + I D L C G P P V W++ ++ + ++ Sbjct: 172 EAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQDVHHGDLHI 231 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI---TISNEDIKQKHKVGDEWLVTA 1594 Y C+A + G + ++ + P I T +++ +K +VG E ++ Sbjct: 232 RGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMAVEVGTEVVLPC 291 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 +G P P V W +NG+ + T S +RI +++ S +YT A N AG Sbjct: 292 EAQGNPSPLVTWSRNGHPIP-PVTAGFTVLPSGS-LRITDVRLIDSKRYTCTAENPAGNV 349 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 S+ L + KP +++ ++VT+ Sbjct: 350 SLSYNLHIQAKPRIQPAATLLKARIGQTVTL 380 Score = 54.0 bits (124), Expect = 4e-05 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++F C G P PQ+ W ++ Q + ++ L I+ PEDAG +TC Sbjct: 98 GEEIRFVCSASGSPPPQLFWSHGNMLLTNRQRLNI----NHYGVLTIKGALPEDAGNYTC 153 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 +A N AG AS + L EAP Sbjct: 154 LATNEAGVASQSVSLTFSEAP 174 Score = 53.6 bits (123), Expect = 6e-05 Identities = 110/543 (20%), Positives = 194/543 (35%), Gaps = 54/543 (9%) Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLT 1217 L+I + DAGEY C G+S+ L V E PS+ + + ++ Sbjct: 48 LQISGVQIQDAGEYHCVATNAHGDSRIIVWLHVPEAPSV--VIHPQSRVFSRGEEIRFVC 105 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 + W ++ + ++ + L I+ +D YTC+ + Sbjct: 106 SASGSPPPQLFWSHGNMLLTNRQRLNINH---YGVLTIKGALPEDAGNYTCLATNEAGVA 162 Query: 1278 KLKVEVV-EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 V + P+I ++ + G+D L P P W + Sbjct: 163 SQSVSLTFSEAPRIRVTQQAIHVSVGADAVLECQATGAPPPLVRWFKGEFEVGSTPFAGQ 222 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 D L I+ V+ DAG Y + G A + + + P G + + + Sbjct: 223 --DVHHGDLHIRGVQEVDAGRYTCVASSPAGTATGTVILKVGAMPKIIGVTSNDKTVKMA 280 Query: 1397 INICWDEP---ENTGN-STIIYYVVEYQEID-TTEWISVKNITKTQTSIQNLKTNSSYRF 1451 + + + E GN S ++ + I T +V + I +++ S R+ Sbjct: 281 VEVGTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTV--LPSGSLRITDVRLIDSKRY 338 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 A N A + Y + + K P ++ + + + L C+ G P P Sbjct: 339 TCTAENP-----AGNVSLSYNLHIQAK---PRIQPAATLLKARIGQTVTLPCVVQGEPSP 390 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 +VTW+ +G + AT Y+C+A N G+ ETS + Sbjct: 391 EVTWFHNGLPVGIKNAT-----PLRIHQAKLGDQGTYRCVATNSAGQ-ETSEI------- 437 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 DI + V G P P++ W++NG LE E + + + + Sbjct: 438 -----KLDILVRRNSAFAHSFVFVNSGSPRPKIRWFRNG--LEIHPEQSDFSVGEDGALV 490 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 I+ SHS +T A+N AG+ + LKV + P P I + ++T+ K PL Sbjct: 491 IRAASASHSGDFTCVATNEAGSVERKTRLKV-NVP-----PEIQDDTQPLNLTVTLKQPL 544 Query: 1692 DDG 1694 G Sbjct: 545 TLG 547 Score = 52.8 bits (121), Expect = 1e-04 Identities = 37/140 (26%), Positives = 55/140 (39%), Gaps = 3/140 (2%) Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574 ++ P GS V C+ G P P +TW + + ++ + D L + +V Sbjct: 1613 QVEPVTIVQGSLVTLSCEARGVPPPTLTWLKDGQPLSLHRNLLL---DGQETRLQLPDVG 1669 Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPP 634 P DAG ++CVA N AG ++ T L V P GS G+PP Sbjct: 1670 PSDAGLYSCVASNQAGSSTKTFNLTVLEPPKMTGSSSPEELFIAVNSPLELECSATGVPP 1729 Query: 635 TFSKKPKAQYVDEGSDILLE 654 K + E DI+ E Sbjct: 1730 PTLTWLKDGHPLERRDIVQE 1749 Score = 51.2 bits (117), Expect = 3e-04 Identities = 31/70 (44%), Positives = 34/70 (48%), Gaps = 5/70 (7%) Query: 535 GYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G PRP+I WFR I P Q DF + D LVIR +G FTCVA N AG Sbjct: 459 GSPRPKIRWFRNGLEIHPEQSDFSVGED----GALVIRAASASHSGDFTCVATNEAGSVE 514 Query: 594 STTELIVEAP 603 T L V P Sbjct: 515 RKTRLKVNVP 524 Score = 50.8 bits (116), Expect = 4e-04 Identities = 28/137 (20%), Positives = 59/137 (43%), Gaps = 3/137 (2%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXX 1538 +SP + + + + L C G P+P ++W R+G + T + + + Sbjct: 2168 ESPEIRPMAEEVQVVLHHGTVLPCEAQGFPRPSISWQREGVPIATGHRLSLLSNGALKFS 2227 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y+C+A N+ G + + P+I+ + ++ G + L++ +G Sbjct: 2228 RVTLGDAGTYQCLAKNEAGAAVGQTKLVLHVPPLISPAQTELSVIQ--GFQALLSCAAQG 2285 Query: 1599 IPPPEVIWYKNGNKLEN 1615 P P++ W KNG+ + N Sbjct: 2286 SPDPKISWEKNGSPVPN 2302 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 +++R P + EC + P P I W++ ++ Q L I+EV Sbjct: 1796 DEVRTVTVPVNGHLTLECLADSDPAPDIEWYKDEVKVQLGGRVQQLAGGQ---YLEIQEV 1852 Query: 574 FPEDAGTFTCVAKNAAGFAS--STTELIVEAPLSDHGSEMT 612 PED+G ++CV N AG +S T E+++ + + SE+T Sbjct: 1853 KPEDSGLYSCVVTNMAGSSSLFFTVEILLPPIIRESSSEVT 1893 Score = 46.4 bits (105), Expect = 0.009 Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +M P F E G ++ C +G P P I+W T P Q + D+ + Sbjct: 2374 NMRPAFKELPGDVTLNKGQSLALSCHAQGTPSPVISW---TVNNSPRQGAAV--DEAGRS 2428 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +L+I V DAGT+ CVA+N G + + + V P Sbjct: 2429 SLIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREP 2465 Score = 45.2 bits (102), Expect = 0.020 Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 H G+ ECQ G P P + WF+ + S F D + L IR V DAG Sbjct: 184 HVSVGADAVLECQATGAPPPLVRWFKGEFEVG-STPFAG--QDVHHGDLHIRGVQEVDAG 240 Query: 580 TFTCVAKNAAGFASSTTELIVEA 602 +TCVA + AG A+ T L V A Sbjct: 241 RYTCVASSPAGTATGTVILKVGA 263 Score = 43.2 bits (97), Expect = 0.081 Identities = 42/172 (24%), Positives = 63/172 (36%), Gaps = 19/172 (11%) Query: 430 VAETDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLN 489 V++ A L+ L +L SN+D Y + E G +E + + + Sbjct: 2015 VSQLSGAFRLLSSGSLVLLSPSNEDEGYFECTAVNEAG--------EERRVIEVILQDGQ 2066 Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 + P S E + + KL P P C V G P+P + W + A Sbjct: 2067 TDVCVFMFCSVPPSIEDDVTAVTAVKLAPAVLP--------CHVHGRPQPTVFWTKGGAK 2118 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + Y L I V P AG +TC A+N+AG A L V+ Sbjct: 2119 LSSRGGT---YRVLPTGLLEITSVLPSHAGRYTCSARNSAGVAHKHVSLSVQ 2167 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 10/75 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV C V+G P P++TWF + N L I + D GT+ C Sbjct: 375 GQTVTLPCVVQGEPSPEVTWFHNGLPV----------GIKNATPLRIHQAKLGDQGTYRC 424 Query: 584 VAKNAAGFASSTTEL 598 VA N+AG +S +L Sbjct: 425 VATNSAGQETSEIKL 439 Score = 38.7 bits (86), Expect = 1.7 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 11/125 (8%) Query: 1074 LYIRNTSVHDEGEYSCILRDESC---TAEVTVVELPPEIITRLQ-NQKVNKGNKATFEIE 1129 L I N + D G Y C+ + T V PP + +Q V +G+ + Sbjct: 2430 LIIENVTTSDAGTYVCVAENRVGSVRTLSFVRVREPPVLKGDAHMSQTVIQGSSTILDCP 2489 Query: 1130 LTKGDA--LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGNSKCT 1186 + GD +++W +DG+ + S+ IQ ++G L IY +++ GEY C N T Sbjct: 2490 I-HGDPSPVLQWLRDGNALLRSHRIQALLNG---SLVIYSVNVNTHEGEYQCLAENEAGT 2545 Query: 1187 AILTV 1191 A T+ Sbjct: 2546 AERTI 2550 Score = 37.9 bits (84), Expect = 3.0 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ C+VEG R +TW+R I D ++L I V +DAG + C Sbjct: 7 GAVAVLSCKVEGSVRHNLTWYRAGRAIGAHTGRSKVLPD---SSLQISGVQIQDAGEYHC 63 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 VA NA G + L + EAP Sbjct: 64 VATNAHGDSRIIVWLHVPEAP 84 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 G+ V C+ +G P P +TW R I P + F + +L I +V D+ +T Sbjct: 284 GTEVVLPCEAQGNPSPLVTWSRNGHPIPPVTAGFTVLPS----GSLRITDVRLIDSKRYT 339 Query: 583 CVAKNAAGFASSTTELIVEA 602 C A+N AG S + L ++A Sbjct: 340 CTAENPAGNVSLSYNLHIQA 359 >UniRef50_Q4SK55 Cluster: Chromosome 2 SCAF14570, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 2 SCAF14570, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1464 Score = 169 bits (410), Expect = 1e-39 Identities = 181/750 (24%), Positives = 311/750 (41%), Gaps = 71/750 (9%) Query: 633 PPTF---SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 P TF S++ + V E ++LL C V+ + + W G E+ N ++ E M Sbjct: 671 PVTFTYISEEDLFKSVVEQEELLLSCE-VSRADGVVQWYKDGTELQQGHNTTIQAEGTMR 729 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIVRQ 748 LKI + + GTYT R G+ V+ K +EPP +I P + + + + Sbjct: 730 Y----LKIHSAQLSGTGTYTC----RTGDN----VIIFKVNVREPPVMIIHPREDVHLER 777 Query: 749 G--ESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVY 803 E +ILS ++ P ++W K+ + ++ + K +G + IL +V+D G Y Sbjct: 778 HVPEEIILSCEL-SRPNGIVSWYKDGQKLQESENIKLKFEGPYRRLKILC-SRVEDSGEY 835 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + + + EP P E+ + + L ++R P Sbjct: 836 VCDTADDSIFFH----LNITEPPVRILSPS---QSQMELCQQTSERMVLSCEISR-PNAV 887 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + WYRN + + + DG L+I + DS +Y C ++ S V I Sbjct: 888 VRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVK-DSAEYVCDTTDD----SMTFFVNI 942 Query: 924 DVEKVTFVKH--LQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGR 980 V F++ + + E G+T++L+C+ S + W N +E+ + I+++G Sbjct: 943 AEPPVRFIRSRKMASAIEKVAGETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGA 1002 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL---QDFEVKEKDVAILE 1037 G C KD ++ VKE + I + + D ILE Sbjct: 1003 IRQLTIHSLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILE 1062 Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 E++ A V W R+G+I+KP ++ ++ +RKL + D G Y C D+ Sbjct: 1063 CEVSRPNATVQWLRNGKILKPD-SRIKIDRYDVVRKLVLSGLQPSDSGTYVCDAIDDQLV 1121 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157 V V E+ + I L+N KG+ T E++K V+W KDG E+ S + Sbjct: 1122 TAVEVQEMMVKFIKPLENTACVKGSSLTLRCEISKLKGDVQWLKDGQEVSSSRRHTIRAQ 1181 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 G+++ + IY +D+G Y CE + + +A +TVE ++ T Sbjct: 1182 GRERSITIYQLVEEDSGVYVCESTHDRTSATVTVETARLSMT------------------ 1223 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 + L + W + I+ ++ + + +KR L I KC D YTC DA TT Sbjct: 1224 ----EHKLSLQW-NNGTEIKPSKDLRIYAMGRKRFLQILKCNVIDSGIYTCDAGDA--TT 1276 Query: 1278 KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 VEV E P IV + S V +L + P+ + W +I + + Sbjct: 1277 SCNVEVYELPVNIVKPLEDKTAFEMSRV-ILDCTVSNPRCSIRWYKGCTVILPSERFEIC 1335 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRL-ENNC 1366 + L I++V DAG Y +++ E +C Sbjct: 1336 SEGGYRKLIIQQVALDDAGTYSVQVGEYSC 1365 Score = 146 bits (353), Expect = 8e-33 Identities = 121/513 (23%), Positives = 214/513 (41%), Gaps = 22/513 (4%) Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 +P +TWY++ + + T +G LV + SG Y C ++ A + Sbjct: 608 DPNAQVTWYKDGIRLHKAAGHTILAEGSKRMLVFESAVLS-HSGIYYCKTTDDAVEFHVD 666 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQ 977 A T T++ E + ++L C+ S +WY + E+ + I Sbjct: 667 A--TAPPVTFTYISEEDLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQA 724 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK--DVAI 1035 EG G C D + V+E I +D ++ + I Sbjct: 725 EGTMRYLKIHSAQLSGTGTYTCRTGDNVIIFKVNVREPPVMIIHPREDVHLERHVPEEII 784 Query: 1036 LEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 L E++ V W +DG+ ++ +N K FE G R+L I + V D GEY C D+ Sbjct: 785 LSCELSRPNGIVSWYKDGQKLQESENIKLKFE--GPYRRLKILCSRVEDSGEYVCDTADD 842 Query: 1095 SCTAEVTVVELPPEIITRLQNQKV---NKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151 S + + E P I++ Q+Q + E+++ +A+VRW+++G E++ +N+ Sbjct: 843 SIFFHLNITEPPVRILSPSQSQMELCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNN 902 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVP 1209 + L +DG ++L I + D+ EY C+ + T + + EP + F + ++ I Sbjct: 903 LILEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKV 962 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 A L E+ +VTW + +ED+ T++ D R L I T +Y C Sbjct: 963 AGETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQYVC- 1021 Query: 1270 LLDAK-STTKLKVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 DAK V+V E P +I+ + + + G D+ L + P +W+ N Sbjct: 1022 --DAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSR-PNATVQWLRNG 1078 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 KI+K K L + ++ +D+G Y Sbjct: 1079 KILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTY 1111 Score = 126 bits (303), Expect = 9e-27 Identities = 132/656 (20%), Positives = 263/656 (40%), Gaps = 31/656 (4%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T + + + V+ G ++L C ++ P + W G + ++ E M Sbjct: 584 TLCEAERKKSVEAGEPLMLRCE-ISDPNAQVTWYKDGIRLHKAAGHTILAEGSKRMLVFE 642 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 + + T AV +A+ P V E E L +V Q E ++L Sbjct: 643 SAVLSHSGIYYCKTTDDAVEFHVDATAPPVTFTYISE-------EDLFKSVVEQ-EELLL 694 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 S +V + W K+ ++ + ++ LK + G T + + Sbjct: 695 SCEV-SRADGVVQWYKDGTELQQGHNTTIQAEGTMRYLKIHSAQLSGTGTYTCRTGDNVI 753 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITWYRNNEII 873 + V EP P + I+ +++ ++ +++ + P ++WY++ + + Sbjct: 754 IFK--VNVREP------PVMIIHPREDVHLERHVPEEIILSCELSRPNGIVSWYKDGQKL 805 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 SE I F+G L I E DSG+Y C ++ + +T ++ Sbjct: 806 QESENIKLKFEGPYRRLKILCSRVE-DSGEYVCDTADDS--IFFHLNITEPPVRILSPSQ 862 Query: 934 LQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 Q + + ++L C+ S +WY N E+ ++ + +G Sbjct: 863 SQMELCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVK 922 Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK---DVAILEVEINSETADVVW 1049 D C D + + + E FIR + EK + +L+ E++ A+V W Sbjct: 923 DSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKVAGETLVLDCEVSRSNAEVTW 982 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 +R+GE ++ +N E G IR+L I + +V G+Y C +D+ V V E P +I Sbjct: 983 KRNGEEMEDSRNITILED-GAIRQLTIHSLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQI 1041 Query: 1110 ITRL---QNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 I ++ + G+ E E+++ +A V+W ++G ++ + I++ +KL + Sbjct: 1042 IGNSGHPEHHTLVAGDDLILECEVSRPNATVQWLRNGKILKPDSRIKIDRYDVVRKLVLS 1101 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 D+G Y C+ + + + V+E + F L V ++ L EI D Sbjct: 1102 GLQPSDSGTYVCDAIDDQLVTAVEVQEMMVKFIKPLENTACVKGSS-LTLRCEISKLKGD 1160 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V W K + + + T+ + ++R++ I + E+D Y C +++ + VE Sbjct: 1161 VQWLKDGQEVSSSRRHTIRAQGRERSITIYQLVEEDSGVYVCESTHDRTSATVTVE 1216 Score = 126 bits (303), Expect = 9e-27 Identities = 165/742 (22%), Positives = 297/742 (40%), Gaps = 70/742 (9%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 +I+L C L + P ++W G+++ ENI + E LKI + G Y Sbjct: 782 EIILSCEL-SRPNGIVSWYKDGQKLQESENIKLKFEGPYRR----LKILCSRVEDSGEY- 835 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIV---RQGESVILSAQVVGNPRPT 765 V + S+ L I EPP +++ P +S + + E ++LS ++ P Sbjct: 836 ---VCDTADDSIFFHLNIT----EPPVRILSPSQSQMELCQQTSERMVLSCEI-SRPNAV 887 Query: 766 ITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + W +N V+ L + DG + I K VKD Y + + + + Sbjct: 888 VRWYRNGLEVEENNNLILEVDGVYRRLIIPKTT-VKDSAEYVCDTTDDS----MTFFVNI 942 Query: 823 EEPTEENAEPPLFINRFQEITVKEK---GTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 EP P FI + + EK T+ L V+R+ +TW RN E + S I Sbjct: 943 AEP------PVRFIRSRKMASAIEKVAGETLVLDCEVSRSNA-EVTWKRNGEEMEDSRNI 995 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 T DG +L I ++ + SG Y C A + +V ++ + + Sbjct: 996 TILEDGAIRQLTIHSL-TVAHSGQYVCDAKDDV--MDFLVKVKEPPVQIIGNSGHPEHHT 1052 Query: 940 TEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 G +ILEC+ S +T +W N K + +I + D G Sbjct: 1053 LVAGDDLILECEVSRPNATVQWLRNGKILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTYV 1112 Query: 999 CIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058 C D + T + V+E + +FI+ L++ + L EI+ DV W +DG+ + Sbjct: 1113 CDAIDDQLVTAVEVQEMMVKFIKPLENTACVKGSSLTLRCEISKLKGDVQWLKDGQEVSS 1172 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKV 1118 + ++ +G R + I D G Y C + +A VTV Sbjct: 1173 SR-RHTIRAQGRERSITIYQLVEEDSGVYVCESTHDRTSATVTV---------------- 1215 Query: 1119 NKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 T + +T+ ++W +G+EI+ S +++ G+K+ L+I C++ D+G Y+C Sbjct: 1216 -----ETARLSMTEHKLSLQW-NNGTEIKPSKDLRIYAMGRKRFLQILKCNVIDSGIYTC 1269 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 + G++ + + V E +N L + + L + + + WYK +VI Sbjct: 1270 DAGDATTSCNVEVYELPVNIVKPLEDKTAFEMSR-VILDCTVSNPRCSIRWYKGCTVILP 1328 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298 +E+F + S+ R LII++ DD Y+ + + + KL VE +V + Sbjct: 1329 SERFEICSEGGYRKLIIQQVALDDAGTYSVQVGEYSCSAKLTVEAQIL--SVVRELEDVE 1386 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + S+ + A W +N + ++ + L +K+ G Sbjct: 1387 VTAPSEACFECEVSAPVVRAPVWSLNGECLQSSSCIRVEKTGAVHRLVLKQTSVDMNG-- 1444 Query: 1359 KLRLENNCGHADVEMNVTILDK 1380 +E CG+A + + +L K Sbjct: 1445 --EIEFTCGNAKSKAQLQVLSK 1464 Score = 115 bits (277), Expect = 1e-23 Identities = 107/456 (23%), Positives = 189/456 (41%), Gaps = 23/456 (5%) Query: 920 RVTIDVE----KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHRE 974 R ++VE ++T + ++ E G+ ++L C+ S WY + + Sbjct: 570 RFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPNAQVTWYKDGIRLHKAAGHT 629 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE----FIRKLQDFE-VK 1029 I+ EG G+ C K + + V T P +I + F+ V Sbjct: 630 ILAEGSKRMLVFESAVLSHSGIYYC--KTTDDAVEFHVDATAPPVTFTYISEEDLFKSVV 687 Query: 1030 EKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 E++ +L E++ V W +DG ++ N + G +R L I + + G Y+C Sbjct: 688 EQEELLLSCEVSRADGVVQWYKDGTELQQGHNT-TIQAEGTMRYLKIHSAQLSGTGTYTC 746 Query: 1090 ILRDESCTAEVTVVELPPEIITRLQNQKVNKG--NKATFEIELTKGDALVRWFKDGSEIQ 1147 D +V V E P II ++ + + + EL++ + +V W+KDG ++Q Sbjct: 747 RTGDNVIIFKVNVREPPVMIIHPREDVHLERHVPEEIILSCELSRPNGIVSWYKDGQKLQ 806 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 S +I+L +G ++LKI ++D+GEY C+ + L + EP + + Sbjct: 807 ESENIKLKFEGPYRRLKILCSRVEDSGEYVCDTADDSIFFHLNITEPPVRILSPSQSQME 866 Query: 1208 VPANTDA--YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCE 1265 + T L+ EI V WY+ +E+ L D R LII K T D E Sbjct: 867 LCQQTSERMVLSCEISRPNAVVRWYRNGLEVEENNNLILEVDGVYRRLIIPKTTVKDSAE 926 Query: 1266 YTCVLLDAKSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDE--WI 1322 Y C D T V + E P + + + I++ + TL++D + + N E W Sbjct: 927 YVCDTTDDSMT--FFVNIAEPPVRFIRSRKMASAIEKVAGETLVLDCEV-SRSNAEVTWK 983 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 N + ++ ++ D LTI + +G Y Sbjct: 984 RNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQY 1019 Score = 87.8 bits (208), Expect = 3e-15 Identities = 207/1010 (20%), Positives = 367/1010 (36%), Gaps = 100/1010 (9%) Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKK 796 +K V +G+ V G P+P I W K+ + + + L + ++ +L K+ Sbjct: 102 VKMFAVTEGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQ 161 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 KD GVY A N+ G ++ ++V+EP P F ++ V E+ L V Sbjct: 162 -KDNGVYVCAASNTAGQTLSAVHLSVKEP------PVRFKQPLIDLEVWERDLAVLECEV 214 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + VP ITWY + + P G L I ++ + D G Y C + G+S Sbjct: 215 PEDSVP-ITWYLEDRRLQPGAKYGMEEWGTKRRLTIRDIGVD-DDGIYLCEMPD-GGRSI 271 Query: 917 HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREI 975 A V + K T ++ L + + EG+ + + WY + E+ H+ I Sbjct: 272 --AEVAV---KGTILRKLPRKVDVLEGENAAYCVEVEKEEMDIHWYKDGVELR-ETHQTI 325 Query: 976 IQE-GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET--IPEFIRKLQDFEVKEKD 1032 I+ GR D G++ +V +TS+ L VK P + + Sbjct: 326 IKSFGRTHILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSARHCPPSCPVGVQINTERAN 385 Query: 1033 VAIL-----EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 A+L + + + V ER E+ + + I SV E +Y Sbjct: 386 AALLSWVPAQDSRRNPPSGYVLERQ-EVGTGSQEWLQCLTTDSATSVEILGDSVPCEADY 444 Query: 1088 SCILRDESCTAEVTVVELPPEI----ITR----LQNQKVNKGNKATFEIELTKGDALVRW 1139 + + + VE P + + R LQ+ V +G A F IEL+ + W Sbjct: 445 RFRICSVNKYGKSNNVEFPRAVHLVPVARIQAPLQDALVPEGQDAFFSIELS-ASVIGTW 503 Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDC-DLDDAGEYSCEVGNSKCTAILTVE------ 1192 F +G+++Q + Q L+I D D+ E + + +A L ++ Sbjct: 504 FLNGTQLQEDERYSMRRTRTHQSLRIRGVRDTDNGAEITFIAYGIRDSAALYIQGVYCCD 563 Query: 1193 --EPSINFTLR---LPEFIL----------VPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237 + I F + LP I V A L EI D VTWYK + Sbjct: 564 AIDDVIRFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPNAQVTWYKDGIRLH 623 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY 1297 T++++ KR L+ Y C D + V+ PP Y E Sbjct: 624 KAAGHTILAEGSKRMLVFESAVLSHSGIYYCKTTD--DAVEFHVDATA-PPVTFTYISEE 680 Query: 1298 RIKRG--SDVTLLVDYQAFPQPN-DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 + + LL+ + +W + +++ +T + L I + + Sbjct: 681 DLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQAEGTMRYLKIHSAQLSG 740 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILE--IDSSSINICWDEPENTGN 1409 G Y R +N + V + + P P + LE + I C E + Sbjct: 741 TGTYTCRTGDNV----IIFKVNVREPPVMIIHPREDVHLERHVPEEIILSC----ELSRP 792 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + I+ + + Q++ +E I + K + + LK S R E A ++ Sbjct: 793 NGIVSWYKDGQKLQESENIKL----KFEGPYRRLKILCS---RVEDSGEYVCDTADDSIF 845 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 ++ I E ++ + + + + +E + L+C P V WYR+G +++ Sbjct: 846 FHLNITEPPVRILSPSQSQMELCQQTSERMVLSCEISR-PNAVVRWYRNGLEVEENNNLI 904 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK-HKVGD 1588 D + + V I + PV I + + KV Sbjct: 905 LEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFIRSRKMASAIEKVAG 964 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 E LV EV W +NG ++E+ + I + I L +HS +Y +A Sbjct: 965 ETLVLDCEVSRSNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIHSLTVAHSGQYVCDAK 1024 Query: 1649 NTAGTSSVEV---TLKVYDKPSKPEGPVIMR--------EISRESVTIEW 1687 + V+V +++ PE ++ E+SR + T++W Sbjct: 1025 DDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSRPNATVQW 1074 Score = 85.4 bits (202), Expect = 2e-14 Identities = 114/469 (24%), Positives = 191/469 (40%), Gaps = 53/469 (11%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S P+ + G D++LEC V+ P + WL G+ + PD I + D + L Sbjct: 1045 SGHPEHHTLVAGDDLILECE-VSRPNATVQWLRNGKILKPDSRIKI----DRYDVVRKLV 1099 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 ++ ++ GTY A++ + +V ++ E + I+PL++ +G S+ L Sbjct: 1100 LSGLQPSDSGTYVCDAIDDQ------LVTAVEVQEMMV-KFIKPLENTACVKGSSLTLRC 1152 Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 ++ + + W K+ + V S H TI + + +Y L E+S Sbjct: 1153 EI-SKLKGDVQWLKDGQEV------SSSRRH--TIRAQGRERSITIYQLVEEDSG----- 1198 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 + V E T + +TV+ T +L +T + + S+ W EI PS Sbjct: 1199 ---VYVCESTHDRTSAT--------VTVE---TARL--SMTEHKL-SLQWNNGTEI-KPS 1240 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + + G L I + IDSG Y C AG ++ V + V VK L+ Sbjct: 1241 KDLRIYAMGRKRFLQILKCNV-IDSGIYTC----DAGDATTSCNVEVYELPVNIVKPLED 1295 Query: 937 SYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 E + VIL+C S+ S +WY I + EI EG D G Sbjct: 1296 KTAFEMSR-VILDCTVSNPRCSIRWYKGCTVILPSERFEICSEGGYRKLIIQQVALDDAG 1354 Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADV-VWERDGE 1054 V + S L V+ I +R+L+D EV A E E+++ VW +GE Sbjct: 1355 TYSVQVGEYSCSAKLTVEAQILSVVRELEDVEVTAPSEACFECEVSAPVVRAPVWSLNGE 1414 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 ++ + EK G + +L ++ TSV GE + A++ V+ Sbjct: 1415 CLQ-SSSCIRVEKTGAVHRLVLKQTSVDMNGEIEFTCGNAKSKAQLQVL 1462 Score = 79.8 bits (188), Expect = 8e-13 Identities = 119/598 (19%), Positives = 225/598 (37%), Gaps = 39/598 (6%) Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK---VNKGNKATFEIELTKGD 1134 + +++ +G Y C D+ V V LP I T + ++ V G E++ + Sbjct: 551 SAALYIQGVYCCDAIDDVIRFNVEVEALPVRITTLCEAERKKSVEAGEPLMLRCEISDPN 610 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 A V W+KDG + + + +G K+ L L +G Y C+ + + P Sbjct: 611 AQVTWYKDGIRLHKAAGHTILAEGSKRMLVFESAVLSHSGIYYCKTTDDAVEFHVDATAP 670 Query: 1195 SINFTLRLPE--FILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + FT E F V + L+ E+ V WYK + ++ T+ ++ R Sbjct: 671 PVTFTYISEEDLFKSVVEQEELLLSCEVSRADGVVQWYKDGTELQQGHNTTIQAEGTMRY 730 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 L I YTC D + KV V E P I+ + ++R +++ + Sbjct: 731 LKIHSAQLSGTGTYTCRTGD--NVIIFKVNVREPPVMIIHPREDVHLERHVPEEIILSCE 788 Query: 1313 AFPQPND--EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 +PN W + + +++ ++ K + L I D+G Y C AD Sbjct: 789 -LSRPNGIVSWYKDGQKLQESENIKLKFEGPYRRLKILCSRVEDSGEYV------CDTAD 841 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + L+ PP + IL S + +C + T ++ + W Sbjct: 842 DSIFFH-LNITEPPVR--ILSPSQSQMELC----QQTSERMVLSCEISRPNA-VVRWY-- 891 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE----TTE----YYKVIKETKIQSP 1482 +N + + + NL +R + + + D++E TT+ ++ I E ++ Sbjct: 892 RNGLEVEEN-NNLILEVDGVYRRLIIPKTTVKDSAEYVCDTTDDSMTFFVNIAEPPVRFI 950 Query: 1483 TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542 K I E + L C +VTW R+G++++ ++ Sbjct: 951 RSRKMASAIEKVAGETLVLDCEVSR-SNAEVTWKRNGEEMEDSRNITILEDGAIRQLTIH 1009 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIP 1600 + D + +V +++ PV I N + H + GD+ ++ + P Sbjct: 1010 SLTVAHSGQYVCDAKDDVMDFLVKVKEPPVQIIGNSGHPEHHTLVAGDDLILECEVSR-P 1068 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 V W +NG L+ D I + + + L+ S S Y +A + ++VEV Sbjct: 1069 NATVQWLRNGKILKPDSRIKIDRYDVVRKLVLSGLQPSDSGTYVCDAIDDQLVTAVEV 1126 Score = 75.4 bits (177), Expect = 2e-11 Identities = 87/390 (22%), Positives = 166/390 (42%), Gaps = 30/390 (7%) Query: 1111 TRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDC 1168 T+++ V +G A F +T K + W KDG I L D + LK+ C Sbjct: 100 TKVKMFAVTEGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYC 159 Query: 1169 DLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 D G Y C N+ + L+V+EP + F L + + + A L E+P+++ Sbjct: 160 KQKDNGVYVCAASNTAGQTLSAVHLSVKEPPVRFKQPLIDLEVWERDL-AVLECEVPEDS 218 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVE- 1282 + +TWY + ++ K+ + KR L IR DD Y C + D +S ++ V+ Sbjct: 219 VPITWYLEDRRLQPGAKYGMEEWGTKRRLTIRDIGVDDDGIYLCEMPDGGRSIAEVAVKG 278 Query: 1283 -VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 ++ P+ VD + G + V+ + + + W + +++ T + Sbjct: 279 TILRKLPRKVD------VLEGENAAYCVEVEK-EEMDIHWYKDGVELRETHQTIIKSFGR 331 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN--- 1398 + L D+GI + + + + + + PP P ++I++ N Sbjct: 332 THILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSA---RHCPPSCPVGVQINTERANAAL 388 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDT--TEWISVKNITKTQTSIQ----NLKTNSSYRFR 1452 + W +++ + YV+E QE+ T EW+ T + TS++ ++ + YRFR Sbjct: 389 LSWVPAQDSRRNPPSGYVLERQEVGTGSQEWLQCLT-TDSATSVEILGDSVPCEADYRFR 447 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSP 1482 +VN+ S+ E ++ +IQ+P Sbjct: 448 ICSVNKYGKSNNVEFPRAVHLVPVARIQAP 477 Score = 53.6 bits (123), Expect = 6e-05 Identities = 25/81 (30%), Positives = 39/81 (48%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G +F C V G P+P+I W + +I + + +Y D + TL + +D G + Sbjct: 109 EGKHAKFRCFVTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQKDNGVYV 168 Query: 583 CVAKNAAGFASSTTELIVEAP 603 C A N AG S L V+ P Sbjct: 169 CAASNTAGQTLSAVHLSVKEP 189 Score = 50.4 bits (115), Expect = 5e-04 Identities = 70/284 (24%), Positives = 109/284 (38%), Gaps = 24/284 (8%) Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612 S F + + D L I + D G +TC A+N G A + L+V+A H E Sbjct: 7 STHFSVGFQDGGWFQLKIFKTRAPDGGVYTCKARNDFGEALAGAVLLVDAG-PGHEEEGN 65 Query: 613 VXXXXXXXXXXXXADILEG--IPP-------TFSKKPKAQYVDEGSDILLECRLVAIPEP 663 G +P T S K K V EG C + P+P Sbjct: 66 RNGYTNCHWKTHQGKPRGGRQMPSRLREDTVTKSTKVKMFAVTEGKHAKFRCFVTGKPKP 125 Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI 723 +I W G I+ + D Y + LK+ K+ G Y A N G+ + Sbjct: 126 EIIWRKDGRLILSGRR--YLLYEDREGYFT-LKVLYCKQKDNGVYVCAASNTAGQTLSAV 182 Query: 724 VLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALP 779 L + KEPP + +PL + V + + +L +V + P ITW ++ P Sbjct: 183 HLSV----KEPPVRFKQPLIDLEVWERDLAVLECEVPEDSVP-ITWYLEDRRLQPGAKYG 237 Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAETSAVITV 822 + G +TI + V D+G+Y + + IAE + T+ Sbjct: 238 MEEWGTKRRLTI-RDIGVDDDGIYLCEMPDGGRSIAEVAVKGTI 280 Score = 49.6 bits (113), Expect = 0.001 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P PE+IW K+G + + + Y + +E +++ K+ + Y ASNTAG + Sbjct: 119 VTGKPKPEIIWRKDGRLILSGRRYLLYEDREGYFTLKVLYCKQKDNGVYVCAASNTAGQT 178 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI-SRESVTIEWKPPLD 1692 V L V + P + + P+I E+ R+ +E + P D Sbjct: 179 LSAVHLSVKEPPVRFKQPLIDLEVWERDLAVLECEVPED 217 Score = 40.7 bits (91), Expect = 0.43 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 6/92 (6%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 V+ L K + S V +C V PR I W++ +I PS+ F++ + L+I++ Sbjct: 1290 VKPLEDKTAFEMSRVILDCTVSN-PRCSIRWYKGCTVILPSERFEI-CSEGGYRKLIIQQ 1347 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 V +DAGT++ G S + +L VEA + Sbjct: 1348 VALDDAGTYSV----QVGEYSCSAKLTVEAQI 1375 Score = 39.1 bits (87), Expect = 1.3 Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 4/155 (2%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ WYK+G +L + I + +T ++ S T + +S + V Sbjct: 308 DIHWYKDGVELRETHQTIIKSFGRTHILVFVNTMPQDSGIVTFLVGRSKTSSQLRVKSAR 367 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVADVD 1720 + PS P G I E + ++ + W P D + Y +E+ E + W++ D Sbjct: 368 HCPPSCPVGVQINTERANAAL-LSWVPAQDSRRNPPSGYVLERQEVGTGSQEWLQCLTTD 426 Query: 1721 RDVETYCI-QKLNENCEYMFRVIAQNPVGFSEALE 1754 + + +Y FR+ + N G S +E Sbjct: 427 SATSVEILGDSVPCEADYRFRICSVNKYGKSNNVE 461 >UniRef50_UPI0000DB720E Cluster: PREDICTED: similar to zormin CG33484-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to zormin CG33484-PA - Apis mellifera Length = 3593 Score = 168 bits (408), Expect = 2e-39 Identities = 182/708 (25%), Positives = 288/708 (40%), Gaps = 70/708 (9%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+ + + P L+ +G +V+ +C + G P P++ W+ +K S DFQ+ + Sbjct: 2039 SDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQG 2098 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 D +LVI E F +DAG + VA N+ G ASS L V + +TV Sbjct: 2099 DK-CSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTV--------TPVTVSEKLDRART 2149 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 + G PP F K P V EG + EC +V P+P++ W E+ +E I + Sbjct: 2150 EIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKWFSDSGEVTENERILI 2209 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLK-----------IKT 729 + D S+LKI++ +G Y V A N GEA +V++ +K Sbjct: 2210 QRKED---GTSILKISSAIPEDKGNYVVKAFNEHGEAKAFARLVIRSLGDFRRKEEFVKM 2266 Query: 730 GEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT 786 EK P E + V +G S VVG P P I W N++PV K GD Sbjct: 2267 EEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKPSPKIQWLFNDRPVHGKDFLVSVSGDR 2326 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 +TI + G + AEN+ G A SA + + + E V++ Sbjct: 2327 QVLTIPETGST-HAGTISCVAENAAGKAICSARLEIGGRSVEE--------------VRK 2371 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 G ++V V R+P + ++E SE +GE V+T + I + Sbjct: 2372 VGEKRVVDLVERSPADEMHAASSSEKHFSSE----KSEGEGESQVLTKMSQTIT----ES 2423 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKE 966 ++ K + + T T K Q+ TV Q+S + Sbjct: 2424 TTTHKTTKKEYISSTT----SSTLSKPGQEPTSVSVKTTVHSTEQSSSENGAPPVVQSYK 2479 Query: 967 ISGMDHREIIQE--GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 + +H +IIQ+ G + G+ + VK + S K T P F+ L Sbjct: 2480 VE--EHEKIIQDQPGEIRQEKTVVVSQDEEGIKQRDVKAAQISKP-TRKSTAPRFVSPLT 2536 Query: 1025 DFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 V + ILE I+ + W ++G+ +K K H+R L ++ +V D Sbjct: 2537 GMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVR-LELKKVNVKD 2595 Query: 1084 EGEYSCILRDE----SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT-KGDAL 1136 G Y+C +E S TA++ V + PP RLQ Q V +G + E+E+T + Sbjct: 2596 AGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPT 2655 Query: 1137 VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 V WFKD I + +++ G L I + AG+Y N+ Sbjct: 2656 VTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNA 2703 Score = 147 bits (356), Expect = 3e-33 Identities = 134/492 (27%), Positives = 205/492 (41%), Gaps = 51/492 (10%) Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 +L D+ YT KL + + +P +E S P FV L G V+ EC+ Sbjct: 1898 FLEDKATYTCKATNKLGQASTSAFLDVEP-AEFTSEKPYFVTPLSNAMGRAGQRVKLECE 1956 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 +G P P +TW+ ++ S + ++ D + LVI E F +DAG +T VAKN AG A Sbjct: 1957 AKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTS-LVISEAFAKDAGCYTVVAKNEAGEA 2015 Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652 + T + V+ L S+ +E + P K V EG + Sbjct: 2016 TVTCNVSVKGRLPHETSD-----------SEFACSDMEPVVPKIQMPLKDLKVQEGLSVR 2064 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L+C +V PEP++ W + + + + + D CS L I G Y VVA Sbjct: 2065 LDCVIVGQPEPEVIWYHDDQPVKESADFQLLFQGDK---CS-LVIHEAFLDDAGVYKVVA 2120 Query: 713 VNREGEASLPIVL---KIKTGEK---------------EPPQVIEPLKSMIVRQGESVIL 754 +N GEAS L + EK PP+ ++ +V +GE+ I Sbjct: 2121 INSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIF 2180 Query: 755 SAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 VVG P+P + W ++ V + + + D SI + +D+G Y +KA N Sbjct: 2181 ECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIPEDKGNYVVKAFNEH 2240 Query: 812 GIAETSAVITV---------EE--PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 G A+ A + + EE EE P F RF++ V E + K V P Sbjct: 2241 GEAKAFARLVIRSLGDFRRKEEFVKMEEKLIAPTFKERFEDRRVMEGVSTKFECIVVGKP 2300 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P I W N+ + + + + G+ L I S +G CVA N+AGK+ AR Sbjct: 2301 SPKIQWLFNDRPVHGKDFLV-SVSGDRQVLTIPETGS-THAGTISCVAENAAGKAICSAR 2358 Query: 921 VTIDVEKVTFVK 932 + I V V+ Sbjct: 2359 LEIGGRSVEEVR 2370 Score = 138 bits (335), Expect = 1e-30 Identities = 171/659 (25%), Positives = 284/659 (43%), Gaps = 81/659 (12%) Query: 306 SIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLFSY-EDIVESK--KDENEII 362 ++++ I ++ +KE K++K V PP +TE + SY +++V S K E I+ Sbjct: 1633 TLEKATIEAKRLKEERKIQK-VSAPPLFSVSAQTEKIETDESYVKEMVTSATIKKEIHIL 1691 Query: 363 QEKQTLEELP-KEDVPEQYTITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGD 421 Q+ + + +P +E P++ IT + + +K E + + ++ F I V+ G+ Sbjct: 1692 QKTEIEKRVPSREPSPQKKIIT--EETREKSVERMHKESVPPLAPEFTIPLHDATVQEGE 1749 Query: 422 TVFAVYSYVAE-TDEAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNY 480 + + + T E I +G + IL+ + Y+ T + + D Y Sbjct: 1750 KFTFQCNLIGQPTPEVIWYKDG--ISILNNPDYLTTYIHGICTLT---IEETFAEDSAKY 1804 Query: 481 TQYLQKKLNEKIDKLPVFEKPTS-EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP 539 T + K T+ EEQ +P+FV++L + S+ Q C V+G P P Sbjct: 1805 TCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLP 1864 Query: 540 QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 + WF+ I S D+ + Y++ A L EVF ED T+TC A N G AS++ L Sbjct: 1865 TVQWFKNDVNIDNSPDYVITYNNGE-AVLKFEEVFLEDKATYTCKATNKLGQASTSAFLD 1923 Query: 600 VEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA 659 VE ++ SE + P + +A G + LEC Sbjct: 1924 VEP--AEFTSEKPYF-----------------VTPLSNAMGRA-----GQRVKLECEAKG 1959 Query: 660 IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719 P P + W G + +E++++ I+ D V+ K G YTVVA N GEA Sbjct: 1960 NPMPALTWYHDGRPV--EESMNLKIQMDGGRTSLVISEAFAK--DAGCYTVVAKNEAGEA 2015 Query: 720 SLPIVLKIK-------------TGEKEP--PQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 ++ + +K + EP P++ PLK + V++G SV L +VG P P Sbjct: 2016 TVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEP 2075 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W +++PVK GD S+ ++ + D GVY + A NS G A + +T Sbjct: 2076 EVIWYHDDQPVKESADFQLLFQGDKCSL-VIHEAFLDDAGVYKVVAINSGGEASSQCTLT 2134 Query: 822 VEEPT------------EEN---AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 V T EE PP F+ + V E T V P P + W Sbjct: 2135 VTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGETAIFECAVVGEPKPELKW 2194 Query: 867 YRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + ++ ++ +E I + DG +I L I++ E D G+Y A N G++ AR+ I Sbjct: 2195 FSDSGEVTENERILIQRKEDGTSI-LKISSAIPE-DKGNYVVKAFNEHGEAKAFARLVI 2251 Score = 126 bits (304), Expect = 7e-27 Identities = 111/433 (25%), Positives = 186/433 (42%), Gaps = 37/433 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P F+ V EG +C L+ P P++ W G I+ + + + + +H Sbjct: 1732 LAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDY---LTTYIHGI 1788 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEP--PQVIEPLKSMIVR 747 C+ L I YT A N G A L +K E++P P ++ L + + Sbjct: 1789 CT-LTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805 + S L+ V GNP PT+ W KN+ + P + +LK ++V +D+ YT Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 KA N G A TSA + VE P E +E P F+ + +KL NP+P++T Sbjct: 1908 KATNKLGQASTSAFLDVE-PAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALT 1966 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-- 923 WY + + S + DG LVI+ ++ D+G Y VA N AG+++ V++ Sbjct: 1967 WYHDGRPVEESMNLKIQMDGGRTSLVISEAFAK-DAGCYTVVAKNEAGEATVTCNVSVKG 2025 Query: 924 --------------DVEKVT-FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKE 966 D+E V ++ K + +EG +V L+C + WYH+ + Sbjct: 2026 RLPHETSDSEFACSDMEPVVPKIQMPLKDLKVQEGLSVRLDCVIVGQPEPEVIWYHDDQP 2085 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETS---TMLVVKETIPEFIR 1021 + +++ +G D GV K + + E S T+ V T+ E + Sbjct: 2086 VKESADFQLLFQGDKCSLVIHEAFLDDAGVYKVVAINSGGEASSQCTLTVTPVTVSEKLD 2145 Query: 1022 KLQDFEVKEKDVA 1034 + + E++E VA Sbjct: 2146 RART-EIEETFVA 2157 Score = 101 bits (241), Expect = 3e-19 Identities = 64/199 (32%), Positives = 102/199 (51%), Gaps = 10/199 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F VD+G+DI+LE + P+P I+W G+E+ + I++ + H+ Sbjct: 2529 PRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHN-HVRLE 2587 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 + K+ NVK G YT A N G AS L +K PP L++ +V++GE V Sbjct: 2588 LKKV-NVK--DAGRYTCTASNEVGSASSTADLVVKK-TIFPPVFGRRLQAQVVKRGERVN 2643 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + ++ G P PT+TW K++ P+K P K G+ + + I K +K G Y ++A N Sbjct: 2644 MEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKA-HAGKYMVRATN 2702 Query: 810 SEGIAETSAVITVEEPTEE 828 + G A++ A V EPT + Sbjct: 2703 AGGEAQSIADFAVFEPTPD 2721 Score = 91.5 bits (217), Expect = 2e-16 Identities = 66/243 (27%), Positives = 109/243 (44%), Gaps = 8/243 (3%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDT 786 T + P+ + PL MIV QG +IL + G P+P+I+W KN + +K T + Sbjct: 2523 TRKSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHN 2582 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 H LK VKD G YT A N G A ++A + V ++ PP+F R Q VK Sbjct: 2583 HVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVV----KKTIFPPVFGRRLQAQVVKR 2638 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 + + +T P P++TW++++ I + N ++I + + +G Y Sbjct: 2639 GERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMV 2698 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKS--YETEEGKTVILECQTSHTVSTKWYHNK 964 A+N+ G++ A + + + K+ YE + K V E + S K Sbjct: 2699 RATNAGGEAQSIADFAVFEPTPDTMTEVHKTVIYENVQDKKVTQETIYTTDQSHKKLETT 2758 Query: 965 KEI 967 K+I Sbjct: 2759 KKI 2761 Score = 74.1 bits (174), Expect = 4e-11 Identities = 73/296 (24%), Positives = 124/296 (41%), Gaps = 19/296 (6%) Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 +V L PE L + V +G K TF+ L + V W+KDG I + T Sbjct: 1728 SVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHG 1787 Query: 1160 KQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFI------LVP 1209 L I + +D+ +Y+C+ G+++ +A LTV+E + P F+ + Sbjct: 1788 ICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847 Query: 1210 ANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 N+ L + L V W+K I+++ + + + + L + +D+ YTC Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907 Query: 1269 V----LLDAKSTTKLKVEVVEFP---PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 L A ++ L VE EF P V + G V L + + P P W Sbjct: 1908 KATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLSNAMGRAGQRVKLECEAKGNPMPALTW 1967 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + + +++ + K +D SL I + DAG Y + +N G A V NV++ Sbjct: 1968 YHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSV 2023 Score = 72.5 bits (170), Expect = 1e-10 Identities = 61/274 (22%), Positives = 106/274 (38%), Gaps = 11/274 (4%) Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 +E E E ++ I K +Q + R + + I++ + ++ KE Sbjct: 1668 IETDESYVKEMVTSATIKKEIHILQKTEIEKRVPSREPSPQKKIITEETREKSVERMHKE 1727 Query: 1477 TKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYENR 1532 + +P PL + T + E C G P P+V WY+DG + TY + Sbjct: 1728 SVPPLAPEFTIPLHDATVQEGEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHG 1787 Query: 1533 X-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C AFN G ETS + +++ + + K + L Sbjct: 1788 ICTLTIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVAL 1847 Query: 1592 ------VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 + ++G P P V W+KN ++N +Y IT +V++ +E+ + YT Sbjct: 1848 ENSSHQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTC 1907 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 +A+N G +S L V E P + +S Sbjct: 1908 KATNKLGQASTSAFLDVEPAEFTSEKPYFVTPLS 1941 Score = 70.5 bits (165), Expect = 5e-10 Identities = 60/259 (23%), Positives = 107/259 (41%), Gaps = 11/259 (4%) Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TY-ENRX 1533 K +P PL + + DI L I G PQP ++W ++G++LKT TY N Sbjct: 2525 KSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHV 2584 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLV 1592 Y C A N+ G ++ + +++ + ++ Q K G+ + Sbjct: 2585 RLELKKVNVKDAGRYTCTASNEVGSASSTADLVVKKTIFPPVFGRRLQAQVVKRGERVNM 2644 Query: 1593 TAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 I G P P V W+K+ + E E I + ++ I + +++H+ KY + A+N Sbjct: 2645 EVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLIIDKAEKAHAGKYMVRATNAG 2704 Query: 1652 GTSSVEVTLKVY----DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL-TKYAIEKH 1706 G + V+ D ++ VI + + VT E D +L T I Sbjct: 2705 GEAQSIADFAVFEPTPDTMTEVHKTVIYENVQDKKVTQETIYTTDQSHKKLETTKKILPP 2764 Query: 1707 EPDNNRWIKVADVDRDVET 1725 P ++++K + D E+ Sbjct: 2765 SPSPSKFVKGEFRESDYES 2783 Score = 64.9 bits (151), Expect = 2e-08 Identities = 36/117 (30%), Positives = 62/117 (52%), Gaps = 3/117 (2%) Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544 ++ + ++ K KPT +S AP FV L G+ + E ++G+P+P I+W Sbjct: 2506 EEGIKQRDVKAAQISKPT--RKSTAPRFVSPLTGMIVDQGTDIILEGIIDGFPQPSISWS 2563 Query: 545 RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + +K + Y ++V L +++V +DAG +TC A N G ASST +L+V+ Sbjct: 2564 KNGQELKTKDGITITYAHNHVR-LELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619 Score = 60.1 bits (139), Expect = 7e-07 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+++ + G P PEVIWYK+G + N+ +Y T + I+E S+KYT + Sbjct: 1748 GEKFTFQCNLIGQPTPEVIWYKDGISILNNPDYLTTYIHGICTLTIEETFAEDSAKYTCK 1807 Query: 1647 ASNTAGTSSVEVTLKVYD--KPSKPEGPVIMREISRESVTIE 1686 A N AG++ TL V + +P PV ++E+ SV +E Sbjct: 1808 AFNIAGSAETSATLTVKETAPEEQPSSPVFVKEL-MASVALE 1848 Score = 58.8 bits (136), Expect = 2e-06 Identities = 53/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%) Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 +I+ S ++ A N ++ S T + E + SP K L N Sbjct: 1792 TIEETFAEDSAKYTCKAFNIAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSS 1851 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK---ATYEN-RXXXXXXXXXXXXXXXYKCIAFN 1554 +L C G P P V W+++ + + TY N Y C A N Sbjct: 1852 HQLNCTVKGNPLPTVQWFKNDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATN 1911 Query: 1555 DHGEVETSCVVGIQ------QKP--VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 G+ TS + ++ +KP V +SN + G + +G P P + W Sbjct: 1912 KLGQASTSAFLDVEPAEFTSEKPYFVTPLSNA----MGRAGQRVKLECEAKGNPMPALTW 1967 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 Y +G +E I + + I E + YT+ A N AG ++V + V Sbjct: 1968 YHDGRPVEESMNLKIQMDGGRTSLVISEAFAKDAGCYTVVAKNEAGEATVTCNVSV 2023 Score = 57.6 bits (133), Expect = 4e-06 Identities = 94/495 (18%), Positives = 180/495 (36%), Gaps = 53/495 (10%) Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL------DA 1273 I T +V WYK I + + TL I + +D +YTC + Sbjct: 1758 IGQPTPEVIWYKDGISILNNPDYLTTYIHGICTLTIEETFAEDSAKYTCKAFNIAGSAET 1817 Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIK---RGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 +T +K E P + +E S L + P P +W N I Sbjct: 1818 SATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFKNDVNIDN 1877 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + ++ A L ++V D Y + N G A + + KP + Sbjct: 1878 SPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLGQASTSAFLDVEPAEFTSEKPYFV 1937 Query: 1391 EIDSSSINICWD----EPENTGNST-IIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLK 1444 S+++ E E GN + + + + ++ + + ++ + +T I Sbjct: 1938 TPLSNAMGRAGQRVKLECEAKGNPMPALTWYHDGRPVEESMNLKIQMDGGRTSLVISEAF 1997 Query: 1445 TNSSYRFRAYAVNEVDISDAS-----------ETTEYYKVIKETKIQSPTVEKPLKNITT 1493 + + A NE + + ET++ + + P ++ PLK++ Sbjct: 1998 AKDAGCYTVVAKNEAGEATVTCNVSVKGRLPHETSDSEFACSDMEPVVPKIQMPLKDLKV 2057 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXY 1548 + + L C+ G P+P+V WY D + +K + A ++ ++ Y Sbjct: 2058 QEGLSVRLDCVIVGQPEPEVIWYHDDQPVKES-ADFQLLFQGDKCSLVIHEAFLDDAGVY 2116 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPV---ITISNEDIKQKHKVGD---------EWLV---- 1592 K +A N GE + C + + V + + +I++ G + LV Sbjct: 2117 KVVAINSGGEASSQCTLTVTPVTVSEKLDRARTEIEETFVAGSPPRFVKLPTDSLVAEGE 2176 Query: 1593 TAVIE----GIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEA 1647 TA+ E G P PE+ W+ + ++ ++ I KE TS+++I Y ++A Sbjct: 2177 TAIFECAVVGEPKPELKWFSDSGEVTENERILIQRKEDGTSILKISSAIPEDKGNYVVKA 2236 Query: 1648 SNTAGTSSVEVTLKV 1662 N G + L + Sbjct: 2237 FNEHGEAKAFARLVI 2251 Score = 50.8 bits (116), Expect = 4e-04 Identities = 29/102 (28%), Positives = 43/102 (42%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F +L+ + G V E ++ G P P +TWF+ IK N L+ Sbjct: 2625 PVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGNCYMLI 2684 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 I + AG + A NA G A S + V P D +E+ Sbjct: 2685 IDKAEKAHAGKYMVRATNAGGEAQSIADFAVFEPTPDTMTEV 2726 Score = 48.8 bits (111), Expect = 0.002 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F ++ +AQ V G + +E + PEP + W FK + + + + I+ + C Sbjct: 2624 PPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTW-FKDDVPIKERPPELRIKQQGN--C 2680 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 +L I +K G Y V A N GEA + E P + E K++I Sbjct: 2681 YMLIIDKAEKAHAGKYMVRATNAGGEAQ--SIADFAVFEPTPDTMTEVHKTVI 2731 Score = 48.0 bits (109), Expect = 0.003 Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 6/162 (3%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE 1282 ++W K ++ + T+ L ++K D YTC + A ST L V+ Sbjct: 2560 ISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSK 1341 FPP + +KRG V + V+ P+P W + IK + + Sbjct: 2620 KTIFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIKERPPELRIKQQGN 2679 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 L I K E AG Y +R N G A + + + P+P Sbjct: 2680 CYMLIIDKAEKAHAGKYMVRATNAGGEAQSIADFAVFE-PTP 2720 Score = 44.0 bits (99), Expect = 0.046 Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 19/209 (9%) Query: 1000 IVKDQETSTMLVVKETIPE-------FIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 I ETS L VKET PE F+++L E L + V Sbjct: 1811 IAGSAETSATLTVKETAPEEQPSSPVFVKELMASVALENSSHQLNCTVKGNPLPTVQWFK 1870 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------SCTAEVTVVEL- 1105 ++ Y L + D+ Y+C ++ S +V E Sbjct: 1871 NDVNIDNSPDYVITYNNGEAVLKFEEVFLEDKATYTCKATNKLGQASTSAFLDVEPAEFT 1930 Query: 1106 --PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P +T L N G + E E KG+ + + W+ DG ++ S ++++ +DG + Sbjct: 1931 SEKPYFVTPLSNAMGRAGQRVKLECE-AKGNPMPALTWYHDGRPVEESMNLKIQMDGGRT 1989 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190 L I + DAG Y+ N A +T Sbjct: 1990 SLVISEAFAKDAGCYTVVAKNEAGEATVT 2018 Score = 40.7 bits (91), Expect = 0.43 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575 G T +FEC V+ P+P I W + II+ S ++++Y + V L I FP Sbjct: 3351 GQTARFECIVQAEPQPNILWSKDGRIIENSSCYEIHY-RNGVCRLTIVRAFP 3401 Score = 40.3 bits (90), Expect = 0.57 Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 14/112 (12%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 + W K+G E++ + I +T +L++ ++ DAG Y+C EVG++ TA L V+ Sbjct: 2560 ISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEVGSASSTADLVVK 2619 Query: 1193 E---PSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIED 1238 + P + F RL + +V + VEI P+ T VTW+K I++ Sbjct: 2620 KTIFPPV-FGRRL-QAQVVKRGERVNMEVEITGTPEPT--VTWFKDDVPIKE 2667 Score = 39.1 bits (87), Expect = 1.3 Identities = 23/86 (26%), Positives = 35/86 (40%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + +G+D+ L FPQP+ W N + +K + L +KKV DAG Y Sbjct: 2540 VDQGTDIILEGIIDGFPQPSISWSKNGQELKTKDGITITYAHNHVRLELKKVNVKDAGRY 2599 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384 N G A ++ + PP Sbjct: 2600 TCTASNEVGSASSTADLVVKKTIFPP 2625 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 6/105 (5%) Query: 1420 QEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 QE+ T + I++ + ++ + + R+ A NEV AS T + V+K+T Sbjct: 2567 QELKTKDGITITYAHNHVRLELKKVNVKDAGRYTCTASNEV--GSASSTADL--VVKKT- 2621 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 I P + L+ + E + + G P+P VTW++D +K Sbjct: 2622 IFPPVFGRRLQAQVVKRGERVNMEVEITGTPEPTVTWFKDDVPIK 2666 >UniRef50_Q4RE91 Cluster: Chromosome undetermined SCAF15134, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF15134, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1216 Score = 167 bits (406), Expect = 3e-39 Identities = 271/1166 (23%), Positives = 469/1166 (40%), Gaps = 88/1166 (7%) Query: 154 EKS--DLFDSQEDESKP-DVSQPPQNIIEEAKS--EPKLIEESEQPIAKTSEIDNEVPEK 208 EKS D + Q KP D P++ +EEAK+ E K I EQ + VP K Sbjct: 56 EKSPPDEKEPQAKVPKPADKKISPESALEEAKAPAEIKKIPTQEQEMESVRLKPISVPSK 115 Query: 209 I-NVPDDKETSQTPTSFNKRSKL-TPIKIER-KEMEVSTPQHAETVDGPQFXXXXXXXXX 265 + P+ K + T +L + I +E+ KE E Q+ + Sbjct: 116 VVGEPEKKPLEKKDTKAVDDKQLHSRISVEKPKEQEPGLKQNKAEIPEAAEKKPEKTPEV 175 Query: 266 XXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKK 325 E + LP K + P + K +IS + K+ +L+ +K+ KV+ Sbjct: 176 KTVREEEKVHALPPSIEKLEKTPEEAKPLQLKKGVISKLKVEKEEVVLTP-VKQLKKVQL 234 Query: 326 QVFVPPKLPDVEKTELEQPLFSYEDIVESKKDENEII-----QEKQTLEELPKEDVPEQY 380 + PK VEK + QP+ S E I K + I + + ++++ K+ +PE+ Sbjct: 235 KKTPSPK---VEKPKEAQPI-SVEKIPGRDKLKKVPITDTPKESAEAMKKVLKKSLPEEE 290 Query: 381 TITPRKSSAQKIDEIVDEVTIKKRLNPFEIFYTPVEVRCGDTVFAV-YSYVAETDEAINL 439 I P +K+D+ +++ I K ++P + + + + VF + E + Sbjct: 291 KIAP----PEKLDK--EKIPIVKEVSPGAVQMKKIATQPEEEVFEEEFGVEEEAVQEEGE 344 Query: 440 VEGERLYILDT-SNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVF 498 V G L ++ ++DW + E V + + + + L P Sbjct: 345 VWGWELVPQESYGSEDWEGEGEDGALEVPGVTRRARQTPSP-GEGRGRGLKPGGRGTPPP 403 Query: 499 EKPTSEEQSMA-PI-FVEKLRP---KHTPD-GSTVQFECQVEGYPRPQIT-WFRQTAIIK 551 E+P + A P+ F++KL+ K GS+ FEC+V P +T W + ++ Sbjct: 404 EEPFGGFKLKAVPLKFIKKLQDIVLKEAESIGSSAVFECEVS--PSTAVTSWMKDGGNLR 461 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-------APL 604 S + + D L I +V D G +TCVAKNA S +LIVE L Sbjct: 462 ESPKHK-FTSDGKDRKLNIIDVQLSDTGEYTCVAKNAGKEISCMAKLIVEELPVKWIKEL 520 Query: 605 SDHGSEMTVXXXXXXXXXXXXADIL---EG-IPPTFSKKPKAQYVDEGSDILLECRLVAI 660 + S + D++ +G + + K + + + LE I Sbjct: 521 EEETSALKGQPLYVTCELNKERDVIWKKDGEVLKKKAGKIQINVIXTTARFELELSHENI 580 Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P + W +I P + ++ H VL+I V + T + A + Sbjct: 581 P---VTWYKNDAKIHPSRTVLTHVDGKRH----VLEIKEVT--LDDTCQIKAEAK----G 627 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKA 777 +P + + E + ++ L+ + + V+L ++ N + W N +P K Sbjct: 628 IPSMANLTVIEGDAYFTVK-LQDYTAVEKDKVVLDCEL--NKDVDVMWYHNEAEIRPSKM 684 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 + K+DG S+ I + KDEG Y G +TSA + ++ A + Sbjct: 685 VSIKADGKRRSLIISRVTD-KDEGQYVCDC----GTDKTSATLHIK------ARHIKVLR 733 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 V E T + ++ + V W N E++SPS I DG LV+ N Sbjct: 734 PMYGAEVFEGETARFEVELSEDDVHG-QWSLNGELLSPSSDIEIVEDGPKHTLVLYNCRV 792 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS 957 +G+ A+N+ K S A + + ++F+ L Y E+ + E + S Sbjct: 793 P-QTGEVVFTAANA--KCS--ANLKVKEIPISFITPLADVYVYEKDE-ARFELEISREPK 846 Query: 958 T-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016 +W +E+ D E++ EG+ D +D+ TS L ++ Sbjct: 847 NFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQGIR 906 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 +FI+ ++D VKE++ A E++ E VVW ++ + P K + E G + L Sbjct: 907 LDFIKPIKDVTVKERETAEFSTELSHEKIPVVWYKNEVRLHPSKVVHITED-GKVHMLAF 965 Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136 + +V D +S A +TV+E +LQN + ++A EL+K A Sbjct: 966 KELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKATAD 1025 Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196 V+WFKDG E+ S +I + DGKK+ L I AG Y+C K T+ L +EE I Sbjct: 1026 VKWFKDGEEVFPSKNILIKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIEEREI 1085 Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256 L + T + T EI + + TW K + + + + + LI+ Sbjct: 1086 KVVRPLYSVEVTETETAKFET-EISERDIHATWKLKGETLHPSADVEIKEEGARHMLILF 1144 Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVE 1282 C +D + +AKS+ +L+V+ Sbjct: 1145 NCKKDMAGGVDFLAANAKSSAQLRVK 1170 Score = 165 bits (401), Expect = 1e-38 Identities = 157/664 (23%), Positives = 282/664 (42%), Gaps = 53/664 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSA--QVVGNPRPTIT-WCKNNKPVKALPTK---SDGDTH 787 P + I+ L+ +++++ ES+ SA + +P +T W K+ ++ P SDG Sbjct: 416 PLKFIKKLQDIVLKEAESIGSSAVFECEVSPSTAVTSWMKDGGNLRESPKHKFTSDGKDR 475 Query: 788 SITILKPKKVKDEGVYTLKAENS--------EGIAETSAVITVEEPTEENAE---PPLFI 836 + I+ + + D G YT A+N+ + I E V ++E EE + PL++ Sbjct: 476 KLNIIDVQ-LSDTGEYTCVAKNAGKEISCMAKLIVEELPVKWIKELEEETSALKGQPLYV 534 Query: 837 ----NRFQEITVKEKGTI--KLVARVTRNPVPS--------------ITWYRNNEIISPS 876 N+ +++ K+ G + K ++ N + + +TWY+N+ I PS Sbjct: 535 TCELNKERDVIWKKDGEVLKKKAGKIQINVIXTTARFELELSHENIPVTWYKNDAKIHPS 594 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 T+ + DG+ L I E+ D + + + G S A +T+ F LQ Sbjct: 595 RTVLTHVDGKRHVLEI----KEVTLDDTCQIKAEAKGIPSM-ANLTVIEGDAYFTVKLQ- 648 Query: 937 SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 Y E V+L+C+ + V WYHN+ EI I +G+ D G Sbjct: 649 DYTAVEKDKVVLDCELNKDVDVMWYHNEAEIRPSKMVSIKADGKRRSLIISRVTDKDEGQ 708 Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 C +TS L +K + +R + EV E + A EVE++ + W +GE++ Sbjct: 709 YVCDCGTDKTSATLHIKARHIKVLRPMYGAEVFEGETARFEVELSEDDVHGQWSLNGELL 768 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 P + + + G L + N V GE + C+A + V E+P IT L + Sbjct: 769 SPSSD-IEIVEDGPKHTLVLYNCRVPQTGEVVFTAANAKCSANLKVKEIPISFITPLADV 827 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V + ++A FE+E+++ RW K E+ + +L ++GKK L I +D +Y Sbjct: 828 YVYEKDEARFELEISREPKNFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKY 887 Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 + E + + + L ++ ++F + + + V A + E+ E + V WYK + + Sbjct: 888 TFEAEDKRTSGKLFIQGIRLDFIKPIKD-VTVKERETAEFSTELSHEKIPVVWYKNEVRL 946 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFPPKIVDYE 1294 ++ + D K L ++ T DD + S L V V F K+ +Y Sbjct: 947 HPSKVVHITEDGKVHMLAFKELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYT 1006 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 + D +L + + +W + + + K+ D K L IKK + Sbjct: 1007 AVEK-----DEAILSCELSKATADVKWFKDGEEVFPSKNILIKSDGKKRMLVIKKAAKSS 1061 Query: 1355 AGIY 1358 AG Y Sbjct: 1062 AGTY 1065 Score = 141 bits (341), Expect = 2e-31 Identities = 138/573 (24%), Positives = 237/573 (41%), Gaps = 24/573 (4%) Query: 945 TVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 T E + SH + WY N +I +G+ D IK K Sbjct: 568 TARFELELSHENIPVTWYKNDAKIHPSRTVLTHVDGKRHVLEIKEVTLDDTCQIKAEAKG 627 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 + L V E F KLQD+ EKD +L+ E+N + DV+W + I+P K Sbjct: 628 IPSMANLTVIEGDAYFTVKLQDYTAVEKDKVVLDCELNKDV-DVMWYHNEAEIRPSK-MV 685 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 + G R L I + DEG+Y C + +A + + +++ + +V +G Sbjct: 686 SIKADGKRRSLIISRVTDKDEGQYVCDCGTDKTSATLHIKARHIKVLRPMYGAEVFEGET 745 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 A FE+EL++ D +W +G + S+ I++ DG K L +Y+C + GE N+ Sbjct: 746 ARFEVELSEDDVHGQWSLNGELLSPSSDIEIVEDGPKHTLVLYNCRVPQTGEVVFTAANA 805 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 KC+A L V+E I+F L + + V +A +EI E + W K + + +KF Sbjct: 806 KCSANLKVKEIPISFITPLAD-VYVYEKDEARFELEISREPKNFRWLKGPQELVNDDKFE 864 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKR 1301 L+ + KK L+I+ +D+ +YT D +++ KL ++ + +F I D + R Sbjct: 865 LLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQGIRLDFIKPIKDVTVKER--E 922 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 ++ + + ++ P W N + K + D K L K++ D + K+ Sbjct: 923 TAEFSTELSHEKIPV---VWYKNEVRLHPSKVVHITEDGKVHMLAFKELTVDDTSMIKVE 979 Query: 1362 LENNCGHA-------DVEMNVTILDKPSPPGKPNIL--EIDSSSINICW-DEPENTGNST 1411 A DV V + + + IL E+ ++ ++ W + E S Sbjct: 980 AMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKATADVKWFKDGEEVFPSK 1039 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I + ++ + K+ T T S KT S + V + E TE Sbjct: 1040 NILIKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIEEREIKVVRPLYSVEVTET 1099 Query: 1471 YKVIKETKIQSPTVEK--PLKNITTEPNEDIEL 1501 ET+I + LK T P+ D+E+ Sbjct: 1100 ETAKFETEISERDIHATWKLKGETLHPSADVEI 1132 Score = 141 bits (341), Expect = 2e-31 Identities = 145/614 (23%), Positives = 259/614 (42%), Gaps = 40/614 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++EG F+ K + E ++L+C L + D+ W EI P + +S+ + Sbjct: 636 VIEG-DAYFTVKLQDYTAVEKDKVVLDCELNK--DVDVMWYHNEAEIRPSKMVSIKADGK 692 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 L I+ V EG Y + A+L I + +V+ P+ V Sbjct: 693 RRS----LIISRVTDKDEGQYVCDCGTDKTSATLHI-------KARHIKVLRPMYGAEVF 741 Query: 748 QGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 +GE+ ++ + W N + P + DG H++ +L +V G Sbjct: 742 EGETARFEVELSEDDVHG-QWSLNGELLSPSSDIEIVEDGPKHTL-VLYNCRVPQTGEVV 799 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N A+ SA + V+E P FI ++ V EK + ++R P + Sbjct: 800 FTAAN----AKCSANLKVKEI------PISFITPLADVYVYEKDEARFELEISREP-KNF 848 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + + + + +G+ L+I + E D Y A + K + G ++ I Sbjct: 849 RWLKGPQELVNDDKFELLVEGKKHILLIKSAKYE-DEAKYTFEAED---KRTSG-KLFIQ 903 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXX 983 ++ F+K + K +E +T + SH + WY N+ + I ++G+ Sbjct: 904 GIRLDFIKPI-KDVTVKERETAEFSTELSHEKIPVVWYKNEVRLHPSKVVHITEDGKVHM 962 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D +IK + + ML V E F KLQ++ EKD AIL E++ Sbjct: 963 LAFKELTVDDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEAILSCELSKA 1022 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 TADV W +DGE + P KN + G R L I+ + G Y+C + T+++ + Sbjct: 1023 TADVKWFKDGEEVFPSKNIL-IKSDGKKRMLVIKKAAKSSAGTYTCSCATDKTTSDLNIE 1081 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 E +++ L + +V + A FE E+++ D W G + S +++ +G + L Sbjct: 1082 EREIKVVRPLYSVEVTETETAKFETEISERDIHATWKLKGETLHPSADVEIKEEGARHML 1141 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE 1223 +++C D AG N+K +A L V+ I+ L + + V A A L+V + E Sbjct: 1142 ILFNCKKDMAGGVDFLAANAKSSAQLRVKARIISLMRPLKD-VTVTAGETATLSVSV-YE 1199 Query: 1224 TLDVTWYKKKSVIE 1237 + V W+ + + +E Sbjct: 1200 GIAVEWFLEGTKLE 1213 Score = 38.7 bits (86), Expect = 1.7 Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 8/95 (8%) Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN--TAGTSSVEV 1658 P W K +L ND ++ + + K ++ IK K +KYT EA + T+G ++ Sbjct: 845 PKNFRWLKGPQELVNDDKFELLVEGKKHILLIKSAKYEDEAKYTFEAEDKRTSGKLFIQG 904 Query: 1659 TLKVYDKPSKP------EGPVIMREISRESVTIEW 1687 + KP K E E+S E + + W Sbjct: 905 IRLDFIKPIKDVTVKERETAEFSTELSHEKIPVVW 939 Score = 37.5 bits (83), Expect = 4.0 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 +D+ K + E+ E IP V+WYKN +L K +IT K ++ KEL Sbjct: 914 KDVTVKERETAEFSTELSHEKIP---VVWYKNEVRLHPSKVVHITEDGKVHMLAFKELTV 970 Query: 1638 SHSSKYTIEA---SNTAGTSSVE------VTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 +S +EA S+ A + +E V L+ Y K E ++ E+S+ + ++W Sbjct: 971 DDTSMIKVEAMGKSSEAMLTVLEGDVYFTVKLQNYTAVEKDEA-ILSCELSKATADVKW 1028 >UniRef50_Q9VZT8 Cluster: CG14964-PA; n=4; Diptera|Rep: CG14964-PA - Drosophila melanogaster (Fruit fly) Length = 1427 Score = 164 bits (398), Expect = 3e-38 Identities = 113/395 (28%), Positives = 177/395 (44%), Gaps = 17/395 (4%) Query: 1380 KPSPPGKPNILEI-----DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-- 1432 +PSPPG+P + + +N+ WD P + G S I Y VE++ + + W+ Sbjct: 12 RPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATPTP 71 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQSPTVEKPLKNI 1491 + + I L+ Y+FR +A N V SDASE ++ V ++ I P L + Sbjct: 72 VDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNAITVPRFIDELVDT 131 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---ENRXXXXXXXXXXXXXXX- 1547 +E IE G P P++ W++DG ++ +++ T +N Sbjct: 132 NAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGE 191 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVIW 1606 KC A N G V T + +Q P I + DE L V + G PPP + W Sbjct: 192 IKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITW 251 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 G + + ++ EK S+++I + R +Y ++A N G S + V +P Sbjct: 252 LHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARP 311 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 + P P + + S T+ W PLDDGG ++ Y +E N W+K A R + T Sbjct: 312 NPPGTPKLNMSFGK-SATLSWTAPLDDGGCKIGNYIVEYFRVGWNVWLKAA-TTRALST- 368 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVI 1760 + L E EY FRV A+NP G SE + ESE + I Sbjct: 369 TLHDLIEGSEYKFRVKAENPYGLSEPSGESELLFI 403 Score = 95.5 bits (227), Expect = 1e-17 Identities = 61/248 (24%), Positives = 103/248 (41%), Gaps = 4/248 (1%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 ++ W+K I + + +++D + L+I + D+ E C + K + V Sbjct: 152 EINWFKDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGEIKCTATNRAGHVITKARLMV 211 Query: 1285 EFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + PPKI YE ++ + L V P P W+ ++I + S K Sbjct: 212 QAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTEK 271 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 ++ L I V D G Y ++ N G VT+ +P+PPG P + S + W Sbjct: 272 NSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARPNPPGTPKLNMSFGKSATLSW 331 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 P + G I Y+VEY + W+ T++ +L S Y+FR A N + Sbjct: 332 TAPLDDGGCKIGNYIVEYFRVGWNVWLKAATTRALSTTLHDLIEGSEYKFRVKAENPYGL 391 Query: 1462 SDASETTE 1469 S+ S +E Sbjct: 392 SEPSGESE 399 Score = 85.4 bits (202), Expect = 2e-14 Identities = 93/408 (22%), Positives = 153/408 (37%), Gaps = 31/408 (7%) Query: 1663 YDKPSKPEGPVI----MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 + +PS P P++ + E + V + W PL DGG +T Y +E + W++ Sbjct: 10 HQRPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATP 69 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVI---KTALDVPSXXXXXX 1774 D CI L Y FR A+N VG S+A E S+P+ + + A+ VP Sbjct: 70 TPVDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNAITVPRFIDELV 129 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT 1834 +++E + F G P EI ++ + S+ Sbjct: 130 DTNAVEDERIE---FRVRILGEPP-----PEINWFKDGYEIFSSRRTKIVNDNEASVLVI 181 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTL--TPPS--QPRNFVVSESTSRSVTLKWTEPE 1890 +Q + EI + + IT + + PP PR + L+ Sbjct: 182 HQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGV 241 Query: 1891 SNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 + P ++ E + + G + T S+ + I+N+ +D + + A N +G Sbjct: 242 AGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLK--IDNVLREDRGEYMVKAWNRLG-- 297 Query: 1950 LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 E + L P+PP P ++ M SW P DGG + Y + V Sbjct: 298 ---EDSTSFLVTVTARPNPPGTP-KLNMSFGKSATLSWTAPLDDGGCKIGNYIVEYFRVG 353 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 +W++ L + DL E Y R+ A N GLSEP E Sbjct: 354 WNVWLKA--ATTRALSTTLHDLIEGSEYKFRVKAENPYGLSEPSGESE 399 Score = 69.3 bits (162), Expect = 1e-09 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 11/218 (5%) Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 +V + E S P+ + ++ P+ I+ L + E + +++G P P I W Sbjct: 97 IVGRSDASELSDPLTVTLQRNAITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWF 156 Query: 770 KNNKPV-KALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 K+ + + TK D S+ ++ + DEG A N G T A + V+ P Sbjct: 157 KDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGEIKCTATNRAGHVITKARLMVQAP-- 214 Query: 828 ENAEPPLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 P + + R E + V+ ++L V P P+ITW E+I+P + Sbjct: 215 ----PKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTE 270 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +N L I NV E D G+Y A N G+ S VT+ Sbjct: 271 KNSLLKIDNVLRE-DRGEYMVKAWNRLGEDSTSFLVTV 307 Score = 62.1 bits (144), Expect = 2e-07 Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 13/193 (6%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 E I R++ P P+I W G EI + +++ SVL I V EG Sbjct: 135 EDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNE----ASVLVIHQVALTDEG 190 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK---SMIVRQGESVILSAQVVGNPR 763 A NR G ++ K + + PP++ P +IV E + L V G P Sbjct: 191 EIKCTATNRAGH----VITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPP 246 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVIT 821 P ITW + + +T ++LK V +D G Y +KA N G TS ++T Sbjct: 247 PAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVT 306 Query: 822 VEEPTEENAEPPL 834 V P L Sbjct: 307 VTARPNPPGTPKL 319 Score = 54.8 bits (126), Expect = 2e-05 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++L + + ++F ++ G P P+I WF+ I S+ ++ +D+ + LV Sbjct: 122 PRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIV-NDNEASVLV 180 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I +V D G C A N AG + L+V+AP Sbjct: 181 IHQVALTDEGEIKCTATNRAGHVITKARLMVQAP 214 Score = 50.0 bits (114), Expect = 7e-04 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 4/100 (4%) Query: 1966 PSPP----TAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDV 2021 PSPP P+ + ++V W P DGG+P+ GY + R + W+ V Sbjct: 13 PSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATPTPV 72 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + I L Y R +A N +G S+ E +P V Sbjct: 73 DRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTV 112 Score = 47.2 bits (107), Expect = 0.005 Identities = 42/167 (25%), Positives = 67/167 (40%), Gaps = 7/167 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P I L + + + F + L + + WFKDG EI S ++ D + L I Sbjct: 122 PRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVI 181 Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEI 1220 + L D GE C G+ A L V+ P I + ++V A+ L V + Sbjct: 182 HQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGV 241 Query: 1221 PDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 + +TW + VI +F + + K L I +D+ EY Sbjct: 242 AGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEY 288 Score = 44.8 bits (101), Expect = 0.026 Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 11/142 (7%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ---YVDEGSDIL-L 653 +I + L+D G E+ A ++ PP + P+ + E ++L L Sbjct: 180 VIHQVALTDEG-EIKCTATNRAGHVITKARLMVQAPPKI-RLPRTYEDGLIVEADEVLRL 237 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 + + P P I WL +GE I P V+ ++ + S+LKI NV + G Y V A Sbjct: 238 KVGVAGQPPPAITWLHEGEVIAPGGRFEVS-NTEKN---SLLKIDNVLREDRGEYMVKAW 293 Query: 714 NREGEASLPIVLKIKTGEKEPP 735 NR GE S ++ + T PP Sbjct: 294 NRLGEDSTSFLVTV-TARPNPP 314 Score = 43.2 bits (97), Expect = 0.081 Identities = 44/191 (23%), Positives = 77/191 (40%), Gaps = 11/191 (5%) Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDG-EIIKP 1058 + D T T+ T+P FI +L D E + V I E ++ W +DG EI Sbjct: 106 LSDPLTVTLQRNAITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSS 165 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES---CTAEVTVVELPPEI-ITRLQ 1114 ++ K + + L I ++ DEGE C + + T +V+ PP+I + R Sbjct: 166 RRTKIVNDNEASV--LVIHQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTY 223 Query: 1115 NQKVNKGNKATFEIELT---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 + +++ + + W +G I +++ K LKI + + Sbjct: 224 EDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLRE 283 Query: 1172 DAGEYSCEVGN 1182 D GEY + N Sbjct: 284 DRGEYMVKAWN 294 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%) Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 V G P P ITW + +I P F++ + N + L I V ED G + A N G Sbjct: 241 VAGQPPPAITWLHEGEVIAPGGRFEVSNTEKN-SLLKIDNVLREDRGEYMVKAWNRLGED 299 Query: 593 SSTTELIVEA 602 S++ + V A Sbjct: 300 STSFLVTVTA 309 >UniRef50_UPI0000F1F64B Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1509 Score = 162 bits (394), Expect = 8e-38 Identities = 225/1049 (21%), Positives = 405/1049 (38%), Gaps = 94/1049 (8%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 +A F+ +L+ + S V FEC+ P ++TW + T IK +++ + Sbjct: 469 LANKFICELKDATADENSDVSFECET-AQPATKVTWLKGTKEIKAGGRYELT-QKGAILI 526 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTE-----LIVEAPLSDHGSEMTVXXXXXXXXX 622 L ++++ D+ +TC + A T + ++ + + Sbjct: 527 LKVKDLEKSDSEVYTCDIGSTKTTAKLTVKEHHYNKLIPSSSQPSNPPSCLLDVKTVKNH 586 Query: 623 XXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 +++ +P F ++ K Q V EG +LL C L + P + W KG E + + Sbjct: 587 FKYMILVQSPVLPAKFKEQMKNQQVTEGEKVLLSCML-SKPGCQVQWK-KGTECLKNGGR 644 Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740 ++ D L+I+ + G Y+ N + A+L + P Sbjct: 645 YQIMQRDTIFE---LQISELAVEDSGEYSCECGNEKTTANLVV-------SALPVVFKHE 694 Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKV 797 L+S G++V L+ ++ P + W K + + + K DG + I K+ Sbjct: 695 LQSQECEGGDTVTLNCEL-SKPGVPVVWKKGTQVLHSGEKYLIKQDGANVELKIAD-LKL 752 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 +D G YT G +T+A I ++ F ++ +E ++ L ++ Sbjct: 753 EDGGQYTCLC----GDKKTTANIKIKALN--------FKRELHDMKCQEADSVTLQCELS 800 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 + VP + W + ++I E G EL I ++ E D+G Y C G + Sbjct: 801 KPGVP-VVWRKGTQVIHSGEKYHIKQVGSTFELKINDLKLE-DAGVYSC----DCGFNKT 854 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREII 976 + +T++ V F LQ + E +EG + L C+ S V +W I I Sbjct: 855 SSTITVNALPVVFTHELQ-NLECDEGGSATLSCELSKPGVPVQWKKGSHIILSGGKYTIK 913 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET---IPEFIRKL---QDFEVKE 1030 Q D G C+ D+ T+ ++ +K P + + + + K+ Sbjct: 914 QIASKVELKIADLKCEDEGEYTCVCGDKTTTAIMKIKALKFLSPSAVAETDSQRQKKDKQ 973 Query: 1031 KDVAILEVEINSETADVVWERDG------EIIKP--------------KKNKYDFEKRGH 1070 +++ L ++ E + V + DG E+ KP KY ++ G Sbjct: 974 AELSALPIKFMQELLNQVGDEDGSVTLCCELSKPGVPVVWRKGTHVLHSGGKYTIKQVGT 1033 Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL 1130 I +L I + D GEY+C D TA + V LP LQNQ+V +G+ T EL Sbjct: 1034 IVELKITDLKPEDAGEYACDCGDNITTASIKVNALPVVFNHELQNQEVQEGDSVTLHCEL 1093 Query: 1131 TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT 1190 +K V W K EI + G +LKI +DAG Y+C+ G++ TA + Sbjct: 1094 SKPGVPVVWRKGTQEIHSGGKYNIKQVGAAVELKIAGVKPEDAGNYACDCGDNITTASIK 1153 Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 V + F+ L +L ++ L E+ + V W K I K+ + D Sbjct: 1154 VNALPVVFSRELQNQVLQEGDS-VTLHCELSKPGVPVVWRKGTQEIHSGGKYNIKQDGAA 1212 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRGSDVTLLV 1309 L I +D +Y C D S+ +KV + P + E + + I+ G VTL Sbjct: 1213 VELKITDVKPEDAGDYICDCGDNISSANIKVNAL---PVVFKRELQNQGIQEGDSVTLCC 1269 Query: 1310 DYQAFPQPNDEWIVNSKIIKK-CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 + P W +++I K++ + S S L I V+ DAG Y + Sbjct: 1270 ELSK-PGVPVTWRKETQVIHSGGKYSIKQVGS-SVELKITDVKPEDAGDYGCDCGESITT 1327 Query: 1369 ADVEMNV-------TILDKPSPPGKPNIL--EIDSSSINICW--DEPENTGNSTIIYYVV 1417 A++ ++ + ++ + G+ E+ I + W D TG + + + Sbjct: 1328 ANIRVDALPAIFTQALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENAVFRCEL 1387 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 W K + + Q + + Y + E D + S TE+ + + Sbjct: 1388 AKSGAKVI-WRKNKRVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQTSAKL 1446 Query: 1478 KIQSP--TVEKPLKNITTEPNEDIELTCI 1504 ++ P T+ LK+ ED+ C+ Sbjct: 1447 TVKEPEITILTGLKSCIVNEGEDVHFECL 1475 Score = 142 bits (344), Expect = 9e-32 Identities = 162/656 (24%), Positives = 264/656 (40%), Gaps = 62/656 (9%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +P F+ + + DEG L C L + P + W KG I+ +S + Sbjct: 860 VNALPVVFTHELQNLECDEGGSATLSCEL-SKPGVPVQWK-KGSHII----LSGGKYTIK 913 Query: 689 HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + V LKI ++K EG YT V G+ + ++KIK + P + S + Sbjct: 914 QIASKVELKIADLKCEDEGEYTCVC----GDKTTTAIMKIKALKFLSPSAVAETDSQRQK 969 Query: 748 QGESVILSA----------QVVGNPRPTITWC-KNNKP-VKALPTKSDGDTHS---ITIL 792 + + LSA VG+ ++T C + +KP V + K HS TI Sbjct: 970 KDKQAELSALPIKFMQELLNQVGDEDGSVTLCCELSKPGVPVVWRKGTHVLHSGGKYTIK 1029 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 + + + + LK E++ A + NA P +F + Q V+E ++ L Sbjct: 1030 QVGTIVELKITDLKPEDAGEYACDCGDNITTASIKVNALPVVFNHELQNQEVQEGDSVTL 1089 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 +++ VP + W + + I G +EL I V E D+G+Y C Sbjct: 1090 HCELSKPGVP-VVWRKGTQEIHSGGKYNIKQVGAAVELKIAGVKPE-DAGNYAC----DC 1143 Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMD 971 G + A + ++ V F + LQ +EG +V L C+ S V W +EI Sbjct: 1144 GDNITTASIKVNALPVVFSRELQNQV-LQEGDSVTLHCELSKPGVPVVWRKGTQEIHSGG 1202 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 I Q+G D G C D +S + V F R+LQ+ ++E Sbjct: 1203 KYNIKQDGAAVELKITDVKPEDAGDYICDCGDNISSANIKVNALPVVFKRELQNQGIQEG 1262 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 D L E++ V W ++ ++I KY ++ G +L I + D G+Y C Sbjct: 1263 DSVTLCCELSKPGVPVTWRKETQVIH-SGGKYSIKQVGSSVELKITDVKPEDAGDYGCDC 1321 Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD--------- 1142 + TA + V LP L+NQ +G +F+ EL+K D V W +D Sbjct: 1322 GESITTANIRVDALPAIFTQALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENA 1381 Query: 1143 ---------GSEI---------QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 G+++ + SN QL DG +L +Y D GEYSCE + + Sbjct: 1382 VFRCELAKSGAKVIWRKNKRVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQ 1441 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 +A LTV+EP I L I+ + + D + V W + +++ E Sbjct: 1442 TSAKLTVKEPEITILTGLKSCIVNEGEDVHFECLVSHDNAVIVQWTLQDVPLQNNE 1497 Score = 136 bits (328), Expect = 8e-30 Identities = 134/569 (23%), Positives = 227/569 (39%), Gaps = 54/569 (9%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILK 793 ++ L ++ V + + +V + W N + +K + + +G H +T K Sbjct: 19 IVRELNTVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKESADIEMEKEGTMHRLTF-K 77 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 K G A S+ +AE + V+E E EP ++ + KEK + L Sbjct: 78 KTKASMSGPVQFTAGKSKSMAE----LKVKERPIEVLEP------LKDASAKEKTSTTLS 127 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 + + P + W++ + S + +++L+I +++E DSG+Y+C A Sbjct: 128 CKFSAPP-KEVNWFKGQTALEASSKYSMKQKDASVQLIIQALNAE-DSGEYRCQAGVCES 185 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDH 972 K+ + VE V E +E + C+ ++ +W N K + + Sbjct: 186 KA------VLKVEDV----------EVDEDGDALFTCEVNYADEEVQWTLNDKPLFNNEV 229 Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKD 1032 I + D G + ++D + + L VKE F++ L D +EK Sbjct: 230 NTITHVDKTHTLSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKG 289 Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 L+ E + VW ++ + K KY+ G L I + + D GEYSC L Sbjct: 290 TVTLKCEASKPRVAPVWRKESTTLSAGK-KYELLHDGKSLGLSIHDITQADAGEYSCDLG 348 Query: 1093 DESCTAEVTVVEL-----------------PPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 + C ++VTV ++ P I LQ G ATF EL++ Sbjct: 349 TDLCKSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGL 408 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEP 1194 V+W KDG I+ S +++ + KL I + D+GEYSCEV G A L ++ Sbjct: 409 EVKWSKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEIKAD 468 Query: 1195 SIN-FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 N F L + N+D E VTW K I+ ++ L L Sbjct: 469 LANKFICELKD-ATADENSDVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILIL 527 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 ++ + D YTC + K+T KL V+ Sbjct: 528 KVKDLEKSDSEVYTCDIGSTKTTAKLTVK 556 Score = 124 bits (300), Expect = 2e-26 Identities = 131/555 (23%), Positives = 222/555 (40%), Gaps = 63/555 (11%) Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 + W GE++ +I + E MH L K G A G++ Sbjct: 48 VKWTLNGEQLKESADIEMEKEGTMHR----LTFKKTKASMSGPVQFTA----GKSKSMAE 99 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-- 782 LK+K + P +V+EPLK ++ S LS + P+ + W K ++A S Sbjct: 100 LKVK---ERPIEVLEPLKDASAKEKTSTTLSCKFSAPPKE-VNWFKGQTALEASSKYSMK 155 Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842 D I++ +D G Y +A G+ E+ AV+ VE+ + Sbjct: 156 QKDASVQLIIQALNAEDSGEYRCQA----GVCESKAVLKVED-----------------V 194 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902 V E G V + W N++ + +E T + L + N+ E D G Sbjct: 195 EVDEDGDALFTCEVNYAD-EEVQWTLNDKPLFNNEVNTITHVDKTHTLSLKNLAPE-DGG 252 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWY 961 S S + + +K F+K L E+G TV L+C+ S V+ W Sbjct: 253 K----VSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKG-TVTLKCEASKPRVAPVWR 307 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET------ 1015 +S E++ +G+ D G C + + + V++ Sbjct: 308 KESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCDLGTDLCKSKVTVRDIHIGITK 367 Query: 1016 -----------IPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064 P ++LQ K + A E++ +V W +DG+ I+ K KY+ Sbjct: 368 RIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGLEVKWSKDGKSIR-KSQKYE 426 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSC-ILRDESCTAEVTV-VELPPEIITRLQNQKVNKGN 1122 + + KL IRN + D GEYSC + + A++ + +L + I L++ ++ + Sbjct: 427 ISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEIKADLANKFICELKDATADENS 486 Query: 1123 KATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 +FE E + V W K EI+ +LT G LK+ D + D+ Y+C++G+ Sbjct: 487 DVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVKDLEKSDSEVYTCDIGS 546 Query: 1183 SKCTAILTVEEPSIN 1197 +K TA LTV+E N Sbjct: 547 TKTTAKLTVKEHHYN 561 Score = 114 bits (274), Expect = 3e-23 Identities = 119/550 (21%), Positives = 207/550 (37%), Gaps = 40/550 (7%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 +N + + + V E V+ V + W N E + S I +G Sbjct: 12 QNEQAISIVRELNTVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKESADIEMEKEGTM 71 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 L + + SG + +AGKS A + + + ++ L+ + E+ T Sbjct: 72 HRLTFKKTKASM-SGPVQF----TAGKSKSMAELKVKERPIEVLEPLKDASAKEKTSTT- 125 Query: 948 LECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 L C+ S W+ + + + Q+ D G +C E+ Sbjct: 126 LSCKFSAPPKEVNWFKGQTALEASSKYSMKQKDASVQLIIQALNAEDSGEYRCQAGVCES 185 Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWE-RDGEIIKPKKNKYDF 1065 +L K++D EV E A+ E+N +V W D + + N Sbjct: 186 KAVL-----------KVEDVEVDEDGDALFTCEVNYADEEVQWTLNDKPLFNNEVNTITH 234 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125 + H L ++N + D G+ S +RD T + V E + L + + T Sbjct: 235 VDKTHT--LSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIFLKLLDDVVAEEKGTVT 292 Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 + E +K W K+ + + +L DGK L I+D DAGEYSC++G C Sbjct: 293 LKCEASKPRVAPVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCDLGTDLC 352 Query: 1186 TAILTVEEPSINFTLRLPEF----------------ILVPANTDAYLTVEIPDETLDVTW 1229 + +TV + I T R+ + DA T E+ L+V W Sbjct: 353 KSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGLEVKW 412 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288 K I ++K+ + + L IR T+ D EY+C + T+K K+E+ + Sbjct: 413 SKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGG-PTSKAKLEIKADLAN 471 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 K + ++ SDV+ + A P W+ +K IK + + L +K Sbjct: 472 KFICELKDATADENSDVSFECE-TAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVK 530 Query: 1349 KVENTDAGIY 1358 +E +D+ +Y Sbjct: 531 DLEKSDSEVY 540 Score = 91.9 bits (218), Expect = 2e-16 Identities = 164/832 (19%), Positives = 329/832 (39%), Gaps = 82/832 (9%) Query: 915 SSHGARVTI--DVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVS-TKWYHNKKEISGM 970 +S+ A++ + + + ++ V+ L + E E E + S TV KW N +++ Sbjct: 2 TSYDAQICLAQNEQAISIVRELN-TVEVTEPFAAHFEVEVSVETVKPVKWTLNGEQLKES 60 Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE 1030 E+ +EG G ++ ++ L VKE E + L+D KE Sbjct: 61 ADIEMEKEGTMHRLTFKKTKASMSGPVQFTAGKSKSMAELKVKERPIEVLEPLKDASAKE 120 Query: 1031 KDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 K L + ++ +V W + G+ +KY +++ +L I+ + D GEY C Sbjct: 121 KTSTTLSCKFSAPPKEVNWFK-GQTALEASSKYSMKQKDASVQLIIQALNAEDSGEYRC- 178 Query: 1091 LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN 1150 + V E + + ++++ +V++ A F E+ D V+W + + F+N Sbjct: 179 --------QAGVCE--SKAVLKVEDVEVDEDGDALFTCEVNYADEEVQWTLNDKPL-FNN 227 Query: 1151 HIQ-LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP 1209 + +T K L + + +D G+ S + + K T L V+E F L+L + ++ Sbjct: 228 EVNTITHVDKTHTLSLKNLAPEDGGKVSFSIRDVKETVCLKVKEKKAIF-LKLLDDVVAE 286 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 L E + W K+ + + +K+ L+ D K L I T+ D EY+C Sbjct: 287 EKGTVTLKCEASKPRVAPVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQADAGEYSCD 346 Query: 1270 LLDAKSTTKLKVEVVEF---------------PPKIVDYEREYRIKRGSDVTLLVDYQAF 1314 L +K+ V + P I + K G D T + Sbjct: 347 LGTDLCKSKVTVRDIHIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQ- 405 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN-CGHADVEM 1373 +W + K I+K + + S + LTI+ V + D+G Y + A +E+ Sbjct: 406 SGLEVKWSKDGKSIRKSQKYEISQEQTLVKLTIRNVTDKDSGEYSCEVTGGPTSKAKLEI 465 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI------DTTE- 1426 + +K K + ++S ++ E E +T + ++ +EI + T+ Sbjct: 466 KADLANKFICELKDATAD-ENSDVSF---ECETAQPATKVTWLKGTKEIKAGGRYELTQK 521 Query: 1427 ----WISVKNITKTQT-----SIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIK 1475 + VK++ K+ + I + KT + + + N++ S S +K Sbjct: 522 GAILILKVKDLEKSDSEVYTCDIGSTKTTAKLTVKEHHYNKLIPSSSQPSNPPSCLLDVK 581 Query: 1476 ETK--------IQSPTV----EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 K +QSP + ++ +KN E + L+C+ P +V W + + LK Sbjct: 582 TVKNHFKYMILVQSPVLPAKFKEQMKNQQVTEGEKVLLSCML-SKPGCQVQWKKGTECLK 640 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSCVVGIQQKPVITISNEDIKQ 1582 Y+ ++ + G +T+ + + PV+ +E Q Sbjct: 641 NG-GRYQIMQRDTIFELQISELAVEDSGEYSCECGNEKTTANLVVSALPVV-FKHELQSQ 698 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 + + GD + + P V+W K L + ++Y I ++I +LK + Sbjct: 699 ECEGGDTVTLNCELSK-PGVPVVWKKGTQVLHSGEKYLIKQDGANVELKIADLKLEDGGQ 757 Query: 1643 YTIEASNTAGTSSVEVTL-----KVYD-KPSKPEGPVIMREISRESVTIEWK 1688 YT + T+++++ +++D K + + + E+S+ V + W+ Sbjct: 758 YTCLCGDKKTTANIKIKALNFKRELHDMKCQEADSVTLQCELSKPGVPVVWR 809 Score = 83.8 bits (198), Expect = 5e-14 Identities = 105/469 (22%), Positives = 185/469 (39%), Gaps = 50/469 (10%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +P F+ + + Q V EG + L C L + P + W +EI ++ Sbjct: 1065 VNALPVVFNHELQNQEVQEGDSVTLHCEL-SKPGVPVVWRKGTQEIHSGGKYNIK----- 1118 Query: 689 HMYCSV-LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + +V LKI VK G Y + AS+ + P L++ +++ Sbjct: 1119 QVGAAVELKIAGVKPEDAGNYACDCGDNITTASIKV-------NALPVVFSRELQNQVLQ 1171 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +G+SV L ++ P + W K + + + + + LK VK E Sbjct: 1172 EGDSVTLHCEL-SKPGVPVVWRKGTQEIHSGGKYNIKQDGAAVELKITDVKPEDAGDYIC 1230 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 + + I+ SA I V NA P +F Q ++E ++ L +++ VP +TW Sbjct: 1231 DCGDNIS--SANIKV------NALPVVFKRELQNQGIQEGDSVTLCCELSKPGVP-VTWR 1281 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA-------- 919 + ++I + G ++EL IT+V E D+GDY C S ++ Sbjct: 1282 KETQVIHSGGKYSIKQVGSSVELKITDVKPE-DAGDYGCDCGESITTANIRVDALPAIFT 1340 Query: 920 -----RVTIDVEKVTFVKHLQK---------SYETEEGKTVILECQTSHT-VSTKWYHNK 964 + ++ E ++F L K ETE G+ + C+ + + W NK Sbjct: 1341 QALKNQTAVEGESISFQCELSKPDIPVEWRRDLETETGENAVFRCELAKSGAKVIWRKNK 1400 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 + I + ++ Q+G D G C + +TS L VKE + L+ Sbjct: 1401 RVIEASNKYQLKQDGAVAELIVYKLQEGDCGEYSCETEHDQTSAKLTVKEPEITILTGLK 1460 Query: 1025 DFEVKEKDVAILEVEINSETADVV-WE-RDGEIIKPKKNKYDFEKRGHI 1071 V E + E ++ + A +V W +D + + NK E RG I Sbjct: 1461 SCIVNEGEDVHFECLVSHDNAVIVQWTLQDVPLQNNEMNKIGMEVRGKI 1509 Score = 62.9 bits (146), Expect = 9e-08 Identities = 39/139 (28%), Positives = 71/139 (51%), Gaps = 4/139 (2%) Query: 1024 QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 +D E + + A+ E+ A V+W ++ +I+ NKY ++ G + +L + D Sbjct: 1371 RDLETETGENAVFRCELAKSGAKVIWRKNKRVIEAS-NKYQLKQDGAVAELIVYKLQEGD 1429 Query: 1084 EGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKD 1142 GEYSC + +A++TV E I+T L++ VN+G FE ++ +A +V+W Sbjct: 1430 CGEYSCETEHDQTSAKLTVKEPEITILTGLKSCIVNEGEDVHFECLVSHDNAVIVQWTLQ 1489 Query: 1143 GSEIQFS--NHIQLTIDGK 1159 +Q + N I + + GK Sbjct: 1490 DVPLQNNEMNKIGMEVRGK 1508 Score = 50.4 bits (115), Expect = 5e-04 Identities = 77/382 (20%), Positives = 148/382 (38%), Gaps = 32/382 (8%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 VDE D L C V + ++ W + + +E ++ H L + N+ + Sbjct: 196 VDEDGDALFTCE-VNYADEEVQWTLNDKPLFNNEVNTITHVDKTH----TLSLKNLAP-E 249 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 +G ++ E + LK+K EK+ ++ L ++ + +V L + PR Sbjct: 250 DGGKVSFSIRDVKET---VCLKVK--EKKAI-FLKLLDDVVAEEKGTVTLKCEA-SKPRV 302 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK-----AENSEGIAET 816 W K + + A DG + ++I + D G Y+ ++ + + Sbjct: 303 APVWRKESTTLSAGKKYELLHDGKSLGLSIHDITQA-DAGEYSCDLGTDLCKSKVTVRDI 361 Query: 817 SAVIT--VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 IT ++ + E P Q ++ K ++++ + + W ++ + I Sbjct: 362 HIGITKRIKSIEAKAGEAPSISKELQGVSAKIGEDATFTCELSQSGL-EVKWSKDGKSIR 420 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVKH 933 S+ + + ++L I NV + DSG+Y C + G + A++ I + F+ Sbjct: 421 KSQKYEISQEQTLVKLTIRNVTDK-DSGEYSCEVT---GGPTSKAKLEIKADLANKFICE 476 Query: 934 LQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 L K +E V EC+T+ + W KEI E+ Q+G Sbjct: 477 L-KDATADENSDVSFECETAQPATKVTWLKGTKEIKAGGRYELTQKGAILILKVKDLEKS 535 Query: 993 DVGVIKCIVKDQETSTMLVVKE 1014 D V C + +T+ L VKE Sbjct: 536 DSEVYTCDIGSTKTTAKLTVKE 557 >UniRef50_Q4SLN7 Cluster: Chromosome 15 SCAF14556, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 15 SCAF14556, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2224 Score = 162 bits (394), Expect = 8e-38 Identities = 151/643 (23%), Positives = 267/643 (41%), Gaps = 40/643 (6%) Query: 750 ESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + +LS V +P+ + W K+ K + + +S G + I ++ KD G Y+ + Sbjct: 1112 QKAVLSCDVT-DPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDSVER-KDAGEYSCE 1169 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGTIKLVARV---TRNPVP 862 GI + + V + +A F N Q+ KE K T+ A + + Sbjct: 1170 V----GIEKLLFKLHVTDLQVRSA----FCN--QDSVQKEIKATVSQKASLCCEVSDSKT 1219 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS---HGA 919 + WY++ +++ S TI G++ LV+ +VD + D+G+Y C A A Sbjct: 1220 EVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKK-DAGEYVCEAGTEKLTFKIHVEAA 1278 Query: 920 RVTIDVEKVTFVKH-LQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEIS--GMDHREI 975 R + + K +Q +T + IL C+ + + KWY + K++S H+E Sbjct: 1279 RAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWYKDGKQLSPSAAVHKEA 1338 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK---LQDFEVKEKD 1032 +G+ D G C+ ++ + + V E F K ++ Sbjct: 1339 --KGKLRQLVIRSTEKKDAGEYTCVAGTEKLAFNVQVAEIKSAFSNKEAVQKEVTAAISQ 1396 Query: 1033 VAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 A L E++ +V W +DG+++ P K + E +G R+L I + D GEY C Sbjct: 1397 KATLGCEVSDLRTEVRWYKDGKLLTPTKTLHT-EVKGKGRQLVIDSIEKKDAGEYICEAG 1455 Query: 1093 DESCTAEVTVVELPPEIITR---LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS 1149 E + V E P + K + KAT E++ V+W+KDG + + Sbjct: 1456 TEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEVSDPKTAVKWYKDGKLLSST 1515 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP-EFILV 1208 + GK ++L I D DAGEY+CE G K L + + ++ F +L E +V Sbjct: 1516 KAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLFKLQMTDAAVRFQKKLDNETCVV 1575 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 A + LT E+ E V W++ ++D++K+ + D R+L+++ D Y+C Sbjct: 1576 QAGENIVLTAELTAENGSVKWFRDGVELKDSKKYEMRKDGFSRSLVVKATETKDSGSYSC 1635 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 D K + KV+V E K V + ++ ++L+ + + W + I Sbjct: 1636 QTTDDK--LEYKVQVKELALKFVVPLKAATVELEGTLSLVCELNQ-ASGDVAWKHKGRDI 1692 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 K + LT+ + D G Y N+ A V Sbjct: 1693 KPGGRYSVRTNGPQRILTVTNISTEDEGDYSCECRNDKTSATV 1735 Score = 146 bits (353), Expect = 8e-33 Identities = 125/528 (23%), Positives = 225/528 (42%), Gaps = 35/528 (6%) Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 KA V+ + L C L D+AW KG +I P SV +L +TN+ Sbjct: 1660 KAATVELEGTLSLVCELNQA-SGDVAWKHKGRDIKPGGRYSVRTNGPQR----ILTVTNI 1714 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 EG Y+ N + A+ + T ++ L ++ +G+ I V Sbjct: 1715 STEDEGDYSCECRNDKTSAT------VSTRAPRQVRLTTKLNNVAAMEGKDAIFKCAVTP 1768 Query: 761 NPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 ++ W + P+ A + G+ HS+T+ + +D G + +AE Sbjct: 1769 ADA-SVRWFHKSLPIAAGIKYKMEHSGNCHSLTVTSVSQ-QDAGEVSFEAEGKS----CK 1822 Query: 818 AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 A + V+ EP +F + + +TV+E+ KL +++ P + W +N+ +I P+ Sbjct: 1823 ANLQVQH------EPVMFKEKLENLTVEEQSEAKLEVELSK-PSEEVRWMKNSVVIQPTG 1875 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 I DG LV +V S D G Y C + + A+++++++K+ +K L ++ Sbjct: 1876 NIKIRTDGAKQALVFMSV-SRADRGVYSCETLDDKTQ----AKLSVEMKKIQVIKGLTET 1930 Query: 938 YETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 E +TV LE + S V W + + + I GR D G Sbjct: 1931 -TAHETETVTLEIELSQADVDGSWTKDGVNVKSGGNCRITALGRKQTLTLSNLKMEDAGT 1989 Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 S L V E + + D V EK+ + E++ +V W +D + Sbjct: 1990 FVFQADGIRVSGKLTVLEPPAMISKPIMDVSVAEKEKVTFDCEVSRTNTEVKWFKDNVEL 2049 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 KP K G R L I + D G Y C D++ +A++TV +I+ +LQ+ Sbjct: 2050 KPGK-MVGIHSLGRKRTLVINKCTPEDAGTYICRTPDDNTSAKLTVNARDIKIVKKLQDV 2108 Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 +V + ATF EL+ + +W+K G++++ S++I++ +G ++ K Sbjct: 2109 EVMEKESATFVCELSHDEVDSQWWKGGTKLKASDNIKMRQEGITKRTK 2156 Score = 131 bits (316), Expect = 2e-28 Identities = 148/626 (23%), Positives = 246/626 (39%), Gaps = 36/626 (5%) Query: 759 VGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 V +P+ + W K+ K KA+ ++S G + I K K KD G YT + + + + Sbjct: 1496 VSDPKTAVKWYKDGKLLSSTKAVHSESKGKIRELVIEKMDK-KDAGEYTCETGTEKLLFK 1554 Query: 816 ---TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 T A + ++ + + V+ I L A +T S+ W+R+ Sbjct: 1555 LQMTDAAVRFQKKLDN-----------ETCVVQAGENIVLTAELTAEN-GSVKWFRDGVE 1602 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + S+ DG + LV+ +++ DSG Y C ++ K + +V + + FV Sbjct: 1603 LKDSKKYEMRKDGFSRSLVVKATETK-DSGSYSCQTTDD--KLEY--KVQVKELALKFVV 1657 Query: 933 HLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 L+ + EG T+ L C+ + W H ++I + G Sbjct: 1658 PLKAATVELEG-TLSLVCELNQASGDVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNIST 1716 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVV 1048 D G C ++ +TS V P +R KL + E AI + + A V Sbjct: 1717 EDEGDYSCECRNDKTSA--TVSTRAPRQVRLTTKLNNVAAMEGKDAIFKCAVTPADASVR 1774 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W I KY E G+ L + + S D GE S +SC A + V P Sbjct: 1775 WFHKSLPIAAGI-KYKMEHSGNCHSLTVTSVSQQDAGEVSFEAEGKSCKANLQVQHEPVM 1833 Query: 1109 IITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 +L+N V + ++A E+EL+K VRW K+ IQ + +I++ DG KQ L Sbjct: 1834 FKEKLENLTVEEQSEAKLEVELSKPSEEVRWMKNSVVIQPTGNIKIRTDGAKQALVFMSV 1893 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT 1228 D G YSCE + K A L+VE I L E T L +E+ +D + Sbjct: 1894 SRADRGVYSCETLDDKTQAKLSVEMKKIQVIKGLTETTAHETET-VTLEIELSQADVDGS 1952 Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP 1288 W K ++ + + +K+TL + +D + + + KL V+E P Sbjct: 1953 WTKDGVNVKSGGNCRITALGRKQTLTLSNLKMEDAGTFVFQADGIRVSGKL--TVLEPPA 2010 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 I + + VT + +W ++ +K K + +L I Sbjct: 2011 MISKPIMDVSVAEKEKVTFDCEVSR-TNTEVKWFKDNVELKPGKMVGIHSLGRKRTLVIN 2069 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMN 1374 K DAG Y R ++ A + +N Sbjct: 2070 KCTPEDAGTYICRTPDDNTSAKLTVN 2095 Score = 130 bits (314), Expect = 4e-28 Identities = 190/913 (20%), Positives = 341/913 (37%), Gaps = 84/913 (9%) Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 I++ K DEG Y+ + + + T + E + + + +V +K T+ Sbjct: 860 IIRNAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKET---VQKEVKASVSQKATL 916 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 T+ V WY++ +++ S TI G +LVI V+ D+G+Y C A Sbjct: 917 SCNVSDTKTEVK---WYKDGKLLISSRTIYSEAKGNTRQLVIEKVEKS-DAGEYTCEAGG 972 Query: 911 S----------AGKSSHGARVTIDVEKVT-FVKHLQKSYETEEG----KTVILECQTSHT 955 SS A V +T F+ L + V + Sbjct: 973 DKLVFTITVTGTRTSSTNACVRQIFNTITLFLPPLHSCFVLPAAIIYYAIVNRHIKIEPL 1032 Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKET 1015 V + ++ + + ++ + +EG+ D G C ++ + V E Sbjct: 1033 VFFCLFPSEAQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICESGSEKLVFRIQVAEA 1092 Query: 1016 IPEFIRK---LQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 F +K +D + A+L ++ +V W +DG+++ + + E +G R Sbjct: 1093 PSAFFKKESIQKDVKASVSQKAVLSCDVTDPKTEVKWYKDGKLLTSTRMVH-VESKGKNR 1151 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-------KVNKGNKAT 1125 +L I + D GEYSC + E ++ V +L ++ + NQ K KA+ Sbjct: 1152 QLVIDSVERKDAGEYSCEVGIEKLLFKLHVTDL--QVRSAFCNQDSVQKEIKATVSQKAS 1209 Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 E++ V+W+KDG + S I GK + L + D DAGEY CE G K Sbjct: 1210 LCCEVSDSKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVCEAGTEKL 1269 Query: 1186 TAILTVE----EPSINFTLRLPEFILVPANT----DAYLTVEIPDETLDVTWYKKKSVIE 1237 T + VE E E + T L+ E+ D +V WYK + Sbjct: 1270 TFKIHVEAARAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWYKDGKQLS 1329 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE--FPPKIVDYER 1295 + + K R L+IR + D EYTCV K ++V ++ F K ++ Sbjct: 1330 PSAAVHKEAKGKLRQLVIRSTEKKDAGEYTCVAGTEKLAFNVQVAEIKSAFSNKEA-VQK 1388 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 E TL + + W + K++ K + K L I +E DA Sbjct: 1389 EVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQLVIDSIEKKDA 1447 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 G Y G V + + + P+ +++ + + + +T+ Sbjct: 1448 GEYIC----EAGTEKVVFRINVAEAPAIFSNKELVKTEVKA--------SLSQKATLSCE 1495 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE---TTEYYK 1472 V + + +W K +S + + + S + R + ++D DA E T K Sbjct: 1496 VSDPK--TAVKWY---KDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEK 1550 Query: 1473 VIKETKIQSPTV--EKPLKNIT--TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 ++ + ++ V +K L N T + E+I LT V W+RDG +LK +K Sbjct: 1551 LLFKLQMTDAAVRFQKKLDNETCVVQAGENIVLTAEL-TAENGSVKWFRDGVELKDSK-K 1608 Query: 1529 YENR-----XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQK 1583 YE R Y C +D E + V + K V+ + ++ + Sbjct: 1609 YEMRKDGFSRSLVVKATETKDSGSYSCQTTDDKLEYKVQ-VKELALKFVVPLKAATVELE 1667 Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 G LV + + +V W G ++ Y++ T ++ + + Y Sbjct: 1668 ---GTLSLVCELNQA--SGDVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNISTEDEGDY 1722 Query: 1644 TIEASNTAGTSSV 1656 + E N +++V Sbjct: 1723 SCECRNDKTSATV 1735 Score = 126 bits (305), Expect = 5e-27 Identities = 136/613 (22%), Positives = 246/613 (40%), Gaps = 37/613 (6%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G +I+L L A + W G E+ + + D V+K T K Sbjct: 1575 VQAGENIVLTAELTA-ENGSVKWFRDGVELKDSKKYEM--RKDGFSRSLVVKATETK--D 1629 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G+Y+ + + E K++ E V+ PLK+ V ++ L ++ Sbjct: 1630 SGSYSCQTTDDKLE------YKVQVKELALKFVV-PLKAATVELEGTLSLVCEL-NQASG 1681 Query: 765 TITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 + W + +K +++G +T+ +DEG Y+ + N + TSA ++ Sbjct: 1682 DVAWKHKGRDIKPGGRYSVRTNGPQRILTVTNIS-TEDEGDYSCECRNDK----TSATVS 1736 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 P + + + E VT S+ W+ + I+ Sbjct: 1737 TRAPRQVR-----LTTKLNNVAAMEGKDAIFKCAVTPADA-SVRWFHKSLPIAAGIKYKM 1790 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 G L +T+V S+ D+G+ V+ + GKS A + + E V F + L+ + E Sbjct: 1791 EHSGNCHSLTVTSV-SQQDAGE---VSFEAEGKSCK-ANLQVQHEPVMFKEKLE-NLTVE 1844 Query: 942 EGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 E LE + S + +W N I + +I +G D GV C Sbjct: 1845 EQSEAKLEVELSKPSEEVRWMKNSVVIQPTGNIKIRTDGAKQALVFMSVSRADRGVYSCE 1904 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 D +T L V+ + I+ L + E + LE+E++ D W +DG +K Sbjct: 1905 TLDDKTQAKLSVEMKKIQVIKGLTETTAHETETVTLEIELSQADVDGSWTKDGVNVKSGG 1964 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNK 1120 N G + L + N + D G + + ++TV+E P I + + V + Sbjct: 1965 N-CRITALGRKQTLTLSNLKMEDAGTFVFQADGIRVSGKLTVLEPPAMISKPIMDVSVAE 2023 Query: 1121 GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 K TF+ E+++ + V+WFKD E++ + + G+K+ L I C +DAG Y C Sbjct: 2024 KEKVTFDCEVSRTNTEVKWFKDNVELKPGKMVGIHSLGRKRTLVINKCTPEDAGTYICRT 2083 Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 + +A LTV I +L + + V A E+ + +D W+K + ++ ++ Sbjct: 2084 PDDNTSAKLTVNARDIKIVKKLQD-VEVMEKESATFVCELSHDEVDSQWWKGGTKLKASD 2142 Query: 1241 KFTLISD-VKKRT 1252 + + + KRT Sbjct: 2143 NIKMRQEGITKRT 2155 Score = 113 bits (273), Expect = 4e-23 Identities = 183/869 (21%), Positives = 321/869 (36%), Gaps = 92/869 (10%) Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019 W N +E+ E + E R DVGV +C++ D S L +K+ +F Sbjct: 743 WMRNGREVKVGKKYEYVSEERKRILLVHNVTEEDVGVYECVLADDSMSIQLALKDEPAKF 802 Query: 1020 IRKLQD---FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 + K + K L ++ +A VVW +D ++ + + F +G RKL I Sbjct: 803 LNKARGPMGLASSLKGDLELSCDVTPASALVVWRKD-QVEITEDQRTIFISKGTQRKLII 861 Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEII-----TRLQNQKVNKGNKATFEIELT 1131 RN DEG YSC + T +V + E T + K + KAT ++ Sbjct: 862 RNAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKETVQKEVKASVSQKATLSCNVS 921 Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 V+W+KDG + S I G ++L I + DAGEY+CE G K +TV Sbjct: 922 DTKTEVKWYKDGKLLISSRTIYSEAKGNTRQLVIEKVEKSDAGEYTCEAGGDKLVFTITV 981 Query: 1192 ---EEPSIN---------FTLRLPEF---ILVPANTDAYLTV--EIPDETL-DVTWYKKK 1233 S N TL LP ++PA Y V I E L + + Sbjct: 982 TGTRTSSTNACVRQIFNTITLFLPPLHSCFVLPAAIIYYAIVNRHIKIEPLVFFCLFPSE 1041 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP---KI 1290 + + ++ + + R L+I D EY C +++V E P K Sbjct: 1042 AQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICE--SGSEKLVFRIQVAEAPSAFFKK 1099 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKV 1350 +++ + L D P+ +W + K++ + K+ L I V Sbjct: 1100 ESIQKDVKASVSQKAVLSCDV-TDPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDSV 1158 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 E DAG Y + G + + + D L++ S+ N D + + Sbjct: 1159 ERKDAGEYSCEV----GIEKLLFKLHVTD----------LQVRSAFCN--QDSVQKEIKA 1202 Query: 1411 TIIYYVVEYQEI-DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE--- 1466 T+ E+ D+ + K S + + T S + R V VD DA E Sbjct: 1203 TVSQKASLCCEVSDSKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVC 1262 Query: 1467 -------TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG---GVPQPKVTWY 1516 T + + ++Q+ + +++ TE + I +V WY Sbjct: 1263 EAGTEKLTFKIHVEAARAEVQAKSAFLNKESVQTEVKTILSQKTILSCELADNATEVKWY 1322 Query: 1517 RDGKKLKTAKATYENR----XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +DGK+L + A ++ Y C+A G + + V + + Sbjct: 1323 KDGKQLSPSAAVHKEAKGKLRQLVIRSTEKKDAGEYTCVA----GTEKLAFNVQVAEIK- 1377 Query: 1573 ITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 SN++ QK + + + + + EV WYK+G L K + K K Sbjct: 1378 SAFSNKEAVQKEVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQ 1436 Query: 1630 IRIKELKRSHSSKYTIEAS--------NTAGTSSV---EVTLKVYDKPSKPEGPVIMREI 1678 + I +++ + +Y EA N A ++ + +K K S + + E+ Sbjct: 1437 LVIDSIEKKDAGEYICEAGTEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEV 1496 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD-RDVETYCIQKLNENCEY 1737 S ++W DG L + A+ R + + +D +D Y + E + Sbjct: 1497 SDPKTAVKW---YKDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLF 1553 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDV 1766 + + V F + L++E V++ ++ Sbjct: 1554 KLQ-MTDAAVRFQKKLDNETCVVQAGENI 1581 Score = 102 bits (245), Expect = 9e-20 Identities = 77/288 (26%), Positives = 128/288 (44%), Gaps = 15/288 (5%) Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEV---KEKDVAILEVEINSETADVVW 1049 D V+K + ++S L VK F K E+ + A L E++ A VVW Sbjct: 684 DGTVVKFVGGGSQSSCTLSVKAPPVRFTNKSVTLELVTCSAQATAQLTAEVSDYDAQVVW 743 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEI 1109 R+G +K K KY++ R L + N + D G Y C+L D+S + ++ + + P + Sbjct: 744 MRNGREVKVGK-KYEYVSEERKRILLVHNVTEEDVGVYECVLADDSMSIQLALKDEPAKF 802 Query: 1110 ITRLQNQK-VNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 + + + + K E+ ++T ALV W KD EI G ++KL I Sbjct: 803 LNKARGPMGLASSLKGDLELSCDVTPASALVVWRKDQVEITEDQRTIFISKGTQRKLIIR 862 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDAYLTVEIPD 1222 + D G YSCE K T + ++E + + + + + + A L+ + D Sbjct: 863 NAKKSDEGHYSCETATDKVTFQVKIKETQSLAAFSHKETVQKEVKASVSQKATLSCNVSD 922 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVK--KRTLIIRKCTEDDQCEYTC 1268 +V WYK ++ + T+ S+ K R L+I K + D EYTC Sbjct: 923 TKTEVKWYKDGKLLISSR--TIYSEAKGNTRQLVIEKVEKSDAGEYTC 968 Score = 95.1 bits (226), Expect = 2e-17 Identities = 118/556 (21%), Positives = 218/556 (39%), Gaps = 41/556 (7%) Query: 1130 LTKGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SK 1184 L KG R DG+ I + H+ + LK+ C D G Y+C N + Sbjct: 270 LPKG-VFTRTCTDGTNISEGRRHVIYEDHAENFILKVLYCKQSDNGLYTCNAANMAGQTY 328 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244 ++TV+EP + F +L + + V A L E+P W+ +++ +E + K+ + Sbjct: 329 SAVLVTVKEPQVPFRRKLQD-VEVQEKKSAMLMCEVPLVATHTNWFMEETRLEQSSKYHM 387 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSD 1304 + R L I T +D Y C + + T K+ R + Sbjct: 388 EQEGTLRRLTIHNVTTNDDGVYICEMKEGSRTVAELTVRGNITKKL---PRRTVVPISDT 444 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 V V+ + P + W NS+ +K+ + + +LTI+ D+G + Sbjct: 445 VIFCVELE-HPCADAYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAF-VAG 502 Query: 1365 NCGHADVEMNVTILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 +C VT K P P I SSI I W P++ I Y+VE +++ Sbjct: 503 DC-KTSTRFTVTAARKHPPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKV 561 Query: 1423 DTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET--TEYYKVIKET 1477 W + IT T+ ++ + +SY+FR A+N+ S E + Y + + E Sbjct: 562 GNKTWQRCNAGETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLEVPGSFYLEPLAE- 620 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY---ENRXX 1534 V K L N T E+ ++ V W DG+ L++ A Y ++ Sbjct: 621 ------VTKGLINSTAVAGEEFSISVGLSAVCSG--FWSLDGRLLRSG-ADYLITRSKTT 671 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 + F G ++SC + ++ PV +N+ + + Sbjct: 672 HTLLIRCVTAEMDGTVVKFVGGGS-QSSCTLSVKAPPV-RFTNKSVTLELVTCSAQATAQ 729 Query: 1595 VIEGIPP--PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + + +V+W +NG +++ K+Y ++E+ ++ + + Y E Sbjct: 730 LTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILLVHNVTEEDVGVY--ECVLADD 787 Query: 1653 TSSVEVTLKVYDKPSK 1668 + S+++ LK D+P+K Sbjct: 788 SMSIQLALK--DEPAK 801 Score = 94.3 bits (224), Expect = 3e-17 Identities = 128/630 (20%), Positives = 244/630 (38%), Gaps = 47/630 (7%) Query: 1140 FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT-AILTVEEPSINF 1198 F ++ F N + +G+ ++L I + DAGEY CE G+ K I E PS F Sbjct: 1038 FPSEAQSAFLNRESVQKEGQSRQLLIDSTERKDAGEYICESGSEKLVFRIQVAEAPSAFF 1097 Query: 1199 TLR-LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 + + + + A L+ ++ D +V WYK ++ T + S K R L+I Sbjct: 1098 KKESIQKDVKASVSQKAVLSCDVTDPKTEVKWYKDGKLLTSTRMVHVESKGKNRQLVIDS 1157 Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAF 1314 D EY+C + K KL V ++ + + +E + +L + Sbjct: 1158 VERKDAGEYSCEVGIEKLLFKLHVTDLQVRSAFCNQDSVQKEIKATVSQKASLCCEVSD- 1216 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY-------KL--RLENN 1365 + +W + K++ + KS L ++ V+ DAG Y KL ++ Sbjct: 1217 SKTEVKWYKDGKLLGSSRTIHTESKGKSRLLVVESVDKKDAGEYVCEAGTEKLTFKIHVE 1276 Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425 A+V+ L+K S + + + +I C E N+T + + + +++ + Sbjct: 1277 AARAEVQAKSAFLNKESVQTEVKTI-LSQKTILSC----ELADNATEVKWYKDGKQLSPS 1331 Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 + + + ++ L S+ + A E +E + + E K E Sbjct: 1332 AAVH----KEAKGKLRQLVIRSTEKKDA---GEYTCVAGTEKLAFNVQVAEIKSAFSNKE 1384 Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545 K +T ++ L C + + +V WY+DGK L K + Sbjct: 1385 AVQKEVTAAISQKATLGCEVSDL-RTEVRWYKDGKLLTPTKTLHTEVKGKGRQLVIDSIE 1443 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 + G + + + + P I + E +K + K T E P + Sbjct: 1444 KKDAGEYICEAGTEKVVFRINVAEAPAIFSNKELVKTEVKASLSQKATLSCEVSDPKTAV 1503 Query: 1606 -WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT----- 1659 WYK+G L + K + +K K + I+++ + + +YT E +++T Sbjct: 1504 KWYKDGKLLSSTKAVHSESKGKIRELVIEKMDKKDAGEYTCETGTEKLLFKLQMTDAAVR 1563 Query: 1660 -LKVYDKPS----KPEGPVIMREISRESVTIEWKPPLDDGGLEL---TKYAIEKHEPDNN 1711 K D + E V+ E++ E+ +++W D G+EL KY + K + Sbjct: 1564 FQKKLDNETCVVQAGENIVLTAELTAENGSVKW---FRD-GVELKDSKKYEMRKDGFSRS 1619 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 +K + +D +Y Q ++ EY +V Sbjct: 1620 LVVKATET-KDSGSYSCQTTDDKLEYKVQV 1648 Score = 89.8 bits (213), Expect = 7e-16 Identities = 63/237 (26%), Positives = 106/237 (44%), Gaps = 15/237 (6%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P+ + K+ V G+ LS VVG+P P ITW ++ + + T DGD + +TI Sbjct: 10 PRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTI 69 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 + ++D G Y +A+N+ G A + + V P E P+F+ + V G + Sbjct: 70 YE-LTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVV 128 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 V RV +P + W ++ + S + D ++ L I V +D G Y C A N+ Sbjct: 129 FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGV-RHLDGGTYTCRAQNT 187 Query: 912 AGKSSHGARVTIDVE----------KVTFVKHLQKSYETEEGKTVILECQTSHTVST 958 AG++ A +T+D + + + HLQK E + I + S S+ Sbjct: 188 AGRAHAAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEESSVTSS 244 Score = 89.8 bits (213), Expect = 7e-16 Identities = 135/674 (20%), Positives = 276/674 (40%), Gaps = 58/674 (8%) Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPE 1108 W DG +++ + Y + L IR + +G + S ++ V+ PP Sbjct: 650 WSLDGRLLRSGAD-YLITRSKTTHTLLIRCVTAEMDGTVVKFVGGGSQSSCTLSVKAPPV 708 Query: 1109 IITR--LQNQKVNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 T + + V +AT ++ E++ DA V W ++G E++ + + +K+ L Sbjct: 709 RFTNKSVTLELVTCSAQATAQLTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILL 768 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVEIPD 1222 +++ +D G Y C + + + L +++ F R P + D L+ ++ Sbjct: 769 VHNVTEEDVGVYECVLADDSMSIQLALKDEPAKFLNKARGPMGLASSLKGDLELSCDVTP 828 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + V W K + I + ++ IS +R LIIR + D+ Y+C K T ++K++ Sbjct: 829 ASALVVWRKDQVEITEDQRTIFISKGTQRKLIIRNAKKSDEGHYSCETATDKVTFQVKIK 888 Query: 1283 ----VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 + F K ++E + TL + + + +W + K++ + Sbjct: 889 ETQSLAAFSHK-ETVQKEVKASVSQKATLSCNV-SDTKTEVKWYKDGKLLISSRTIYSEA 946 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSSS 1396 + L I+KVE +DAG Y + + + T + + N + + Sbjct: 947 KGNTRQLVIEKVEKSDAGEYTCEAGGDKLVFTITVTGTRTSSTNACVRQIFNTITLFLPP 1006 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKT-NSSYRFRAY 1454 ++ C+ P + IIYY + + I + ++ Q++ N ++ + R Sbjct: 1007 LHSCFVLP-----AAIIYYAIVNRHIKIEPLVFFCLFPSEAQSAFLNRESVQKEGQSRQL 1061 Query: 1455 AVNEVDISDASE---TTEYYKVIKETKI-QSPTV----EKPLKNITTEPNEDIELTCIFG 1506 ++ + DA E + K++ ++ ++P+ E K++ ++ L+C Sbjct: 1062 LIDSTERKDAGEYICESGSEKLVFRIQVAEAPSAFFKKESIQKDVKASVSQKAVLSCDVT 1121 Query: 1507 GVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 P+ +V WY+DGK L + + + + D GE SC VG Sbjct: 1122 D-PKTEVKWYKDGKLLTSTRMVH-------VESKGKNRQLVIDSVERKDAGEY--SCEVG 1171 Query: 1567 IQQ---KPVIT-------ISNEDIKQKH-KVGDEWLVTAVIE-GIPPPEVIWYKNGNKLE 1614 I++ K +T N+D QK K + E EV WYK+G L Sbjct: 1172 IEKLLFKLHVTDLQVRSAFCNQDSVQKEIKATVSQKASLCCEVSDSKTEVKWYKDGKLLG 1231 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 + + + +K K+ ++ ++ + + + +Y E AGT ++T K++ + ++ E Sbjct: 1232 SSRTIHTESKGKSRLLVVESVDKKDAGEYVCE----AGTE--KLTFKIHVEAARAEVQAK 1285 Query: 1675 MREISRESVTIEWK 1688 +++ESV E K Sbjct: 1286 SAFLNKESVQTEVK 1299 Score = 82.2 bits (194), Expect = 1e-13 Identities = 113/516 (21%), Positives = 196/516 (37%), Gaps = 33/516 (6%) Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 K D G+YT A N G ++ ++TV+EP + P F + Q++ V+EK + L+ Sbjct: 309 KQSDNGLYTCNAANMAGQTYSAVLVTVKEP-----QVP-FRRKLQDVEVQEKKSAMLMCE 362 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 V W+ + S +G L I NV + D G Y C + Sbjct: 363 VPL-VATHTNWFMEETRLEQSSKYHMEQEGTLRRLTIHNVTTN-DDGVYIC-------EM 413 Query: 916 SHGARVTIDVE-KVTFVKHLQKSYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHR 973 G+R ++ + K L + TVI + H W N +++ Sbjct: 414 KEGSRTVAELTVRGNITKKLPRRTVVPISDTVIFCVELEHPCADAYWTRNSEKLKEGSRV 473 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 I R D G + + D +TST V D + K Sbjct: 474 SIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVTAARKHPPDSPVDAVIHNKTE 533 Query: 1034 AILEVEINSETADVVWERDGEIIKPKK--NK-YDFEKRGH-IRKLYIRNTSVHDEGEYSC 1089 + + ++ + +D G I++ +K NK + G I I S +E Y Sbjct: 534 SSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQRCNAGETITSTEITLCSFAEEASYQF 593 Query: 1090 ILRDESCTAEVTVVELPP----EIITRLQNQKVNKGNKATFEIELTKGDALV---RWFKD 1142 + + + +E+P E + + +N A E ++ G + V W D Sbjct: 594 RISAMNDFGQSPYLEVPGSFYLEPLAEVTKGLINSTAVAGEEFSISVGLSAVCSGFWSLD 653 Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV-GNSKCTAILTVEEPSINFTLR 1201 G ++ +T L I + G V G S+ + L+V+ P + FT + Sbjct: 654 GRLLRSGADYLITRSKTTHTLLIRCVTAEMDGTVVKFVGGGSQSSCTLSVKAPPVRFTNK 713 Query: 1202 --LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 E + A A LT E+ D V W + ++ +K+ +S+ +KR L++ T Sbjct: 714 SVTLELVTCSAQATAQLTAEVSDYDAQVVWMRNGREVKVGKKYEYVSEERKRILLVHNVT 773 Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYER 1295 E+D Y CVL D + +L ++ + P K ++ R Sbjct: 774 EEDVGVYECVLADDSMSIQLALK--DEPAKFLNKAR 807 Score = 75.4 bits (177), Expect = 2e-11 Identities = 61/261 (23%), Positives = 109/261 (41%), Gaps = 8/261 (3%) Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELPPE 1108 DG I + +E L + D G Y+C + ++ +A + V+ P Sbjct: 281 DGTNISEGRRHVIYEDHAENFILKVLYCKQSDNGLYTCNAANMAGQTYSAVLVTVKEPQV 340 Query: 1109 IITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 R LQ+ +V + A E+ WF + + ++ S+ + +G ++L I++ Sbjct: 341 PFRRKLQDVEVQEKKSAMLMCEVPLVATHTNWFMEETRLEQSSKYHMEQEGTLRRLTIHN 400 Query: 1168 CDLDDAGEYSCEVGN-SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 +D G Y CE+ S+ A LTV N T +LP +VP + VE+ D Sbjct: 401 VTTNDDGVYICEMKEGSRTVAELTVRG---NITKKLPRRTVVPISDTVIFCVELEHPCAD 457 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 W + +++ + ++ +++ TL IR C DD E V D K++T+ V Sbjct: 458 AYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVTAARK 517 Query: 1287 PPKIVDYEREYRIKRGSDVTL 1307 P + K S +T+ Sbjct: 518 HPPDSPVDAVIHNKTESSITI 538 Score = 74.1 bits (174), Expect = 4e-11 Identities = 65/220 (29%), Positives = 87/220 (39%), Gaps = 30/220 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G C V G P P ITW R + F+ D D V L I E+ ED+G + C Sbjct: 24 GKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGD-VYRLTIYELTLEDSGQYMC 82 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 AKN G A + L V P +EM P F KP Sbjct: 83 RAKNNVGEAYAAVTLKVALP-----AEMPQRA------------------PVFVVKPATA 119 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V G D++ CR+ A PE + W G + + + +SD S+LKI V+ Sbjct: 120 RVGLGGDVVFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSD----SSILKIQGVRHL 175 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 GTYT A N G A L + ++ +I+P KS Sbjct: 176 DGGTYTCRAQNTAGRAHAAAALTVDA--QDSHSLIKPDKS 213 Score = 68.1 bits (159), Expect = 2e-09 Identities = 64/244 (26%), Positives = 103/244 (42%), Gaps = 13/244 (5%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L G P F +PKA V G D L C +V P P I W ++ + D+ Sbjct: 5 LFGGVPRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDV 64 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744 + L I + G Y A N GEA + LK+ + ++ P V++P + Sbjct: 65 YR----LTIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATAR 120 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEG 801 V G V+ +V +P W K+ + + ++ K D+ S +ILK + V+ D G Sbjct: 121 -VGLGGDVVFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDS-SILKIQGVRHLDGG 178 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 YT +A+N+ G A +A +TV+ + P K K +K + R+ Sbjct: 179 TYTCRAQNTAGRAHAAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEE 238 Query: 862 PSIT 865 S+T Sbjct: 239 SSVT 242 Score = 59.7 bits (138), Expect = 9e-07 Identities = 50/187 (26%), Positives = 77/187 (41%), Gaps = 9/187 (4%) Query: 1200 LRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC 1258 L P+ V DA L+ + T +TW + K + +F + D L I + Sbjct: 13 LTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYEL 72 Query: 1259 TEDDQCEYTCVLL----DAKSTTKLKVEV-VEFP---PKIVDYEREYRIKRGSDVTLLVD 1310 T +D +Y C +A + LKV + E P P V R+ G DV + Sbjct: 73 TLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVVFVCR 132 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 A P+ N EW + + + + K DS S+ L I+ V + D G Y R +N G A Sbjct: 133 VAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNTAGRAH 192 Query: 1371 VEMNVTI 1377 +T+ Sbjct: 193 AAAALTV 199 Score = 58.4 bits (135), Expect = 2e-06 Identities = 37/156 (23%), Positives = 62/156 (39%), Gaps = 2/156 (1%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P + W +N KL+ +I + + I++ + S + A + ++ VT Sbjct: 454 PCADAYWTRNSEKLKEGSRVSIACLLRQYTLTIRDCRADDSGEVAFVAGDCKTSTRFTVT 513 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 P P VI + + S+TI+W PP D + + Y +E + N W + Sbjct: 514 AARKHPPDSPVDAVIHNK-TESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQRCNAG 572 Query: 1720 DRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 + T + E Y FR+ A N G S LE Sbjct: 573 ETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLE 608 Score = 56.8 bits (131), Expect = 6e-06 Identities = 48/193 (24%), Positives = 81/193 (41%), Gaps = 17/193 (8%) Query: 1016 IPEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 +P F+ + + F V KD + + S T + WERD ++ ++ + G + +L Sbjct: 9 VPRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERD-KLKLTSGGRFKTVEDGDVYRL 67 Query: 1075 YIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEI-------ITRLQNQKVNKGNKA 1124 I ++ D G+Y C ++ E+ A V LP E+ + + +V G Sbjct: 68 TIYELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDV 127 Query: 1125 TFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE---- 1179 F + +A W KDG + SN +++ D LKI D G Y+C Sbjct: 128 VFVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNT 187 Query: 1180 VGNSKCTAILTVE 1192 G + A LTV+ Sbjct: 188 AGRAHAAAALTVD 200 Score = 54.8 bits (126), Expect = 2e-05 Identities = 81/357 (22%), Positives = 135/357 (37%), Gaps = 23/357 (6%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 L D Y + + E + + +E AP+FV K G V F C+V Sbjct: 74 LEDSGQYMCRAKNNVGEAYAAVTLKVALPAEMPQRAPVFVVKPATARVGLGGDVVFVCRV 133 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 +P W + + S ++ D D+ + L I+ V D GT+TC A+N AG A Sbjct: 134 AAHPEANFEWEKDGRYLGESNRVKIVSDSDS-SILKIQGVRHLDGGTYTCRAQNTAGRAH 192 Query: 594 STTELIVEAPLS------DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDE 647 + L V+A S D + + I + + D Sbjct: 193 AAAALTVDAQDSHSLIKPDKSTSLLSHLQKRKEEMKKDISIFRSEESSVTSSSVTSITDG 252 Query: 648 GSDILLECRLVAIPEPDIAWLFKG---EEIVPDENISVA---IESDMHMYCSVLKITNVK 701 + LE L A +A L KG NIS + + H +LK+ K Sbjct: 253 LGSLGLEHALRA---STLAMLPKGVFTRTCTDGTNISEGRRHVIYEDHAENFILKVLYCK 309 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + G YT A N G+ +++ +K E + P L+ + V++ +S +L +V Sbjct: 310 QSDNGLYTCNAANMAGQTYSAVLVTVK--EPQVP-FRRKLQDVEVQEKKSAMLMCEVPLV 366 Query: 762 PRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAE 815 T + + + ++ + +G +TI D+GVY + E S +AE Sbjct: 367 ATHTNWFMEETRLEQSSKYHMEQEGTLRRLTI-HNVTTNDDGVYICEMKEGSRTVAE 422 Score = 53.2 bits (122), Expect = 8e-05 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 3/87 (3%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-- 1922 PP P + V+ T S+T++W+ P+S+ PI YI+E + V K+W + G ++ Sbjct: 519 PPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTWQR-CNAGETITS 577 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVS 1949 E + + E+ FRISA N G S Sbjct: 578 TEITLCSFAEEASYQFRISAMNDFGQS 604 Score = 50.0 bits (114), Expect = 7e-04 Identities = 41/177 (23%), Positives = 68/177 (38%), Gaps = 13/177 (7%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX--YKCIA 1552 +D L+C G P P +TW RD KL + T E+ Y C A Sbjct: 25 KDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYELTLEDSGQYMCRA 84 Query: 1553 FNDHGEVETSCVVGI-------QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 N+ GE + + + Q+ PV + + + +G + + + P Sbjct: 85 KNNVGEAYAAVTLKVALPAEMPQRAPVFVV--KPATARVGLGGDVVFVCRVAAHPEANFE 142 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 W K+G L I + +S+++I+ ++ YT A NTAG + L V Sbjct: 143 WEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTCRAQNTAGRAHAAAALTV 199 Score = 49.2 bits (112), Expect = 0.001 Identities = 41/174 (23%), Positives = 68/174 (39%), Gaps = 13/174 (7%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P +TR + V G AT + L+ W +D ++ + DG +L I Sbjct: 10 PRFLTRPKAFSVCVGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTI 69 Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI- 1220 Y+ L+D+G+Y C VG + L V P+ R P F++ PA L ++ Sbjct: 70 YELTLEDSGQYMCRAKNNVGEAYAAVTLKVALPA-EMPQRAPVFVVKPATARVGLGGDVV 128 Query: 1221 ------PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 + W K + ++ + ++SD L I+ D YTC Sbjct: 129 FVCRVAAHPEANFEWEKDGRYLGESNRVKIVSDSDSSILKIQGVRHLDGGTYTC 182 Score = 43.2 bits (97), Expect = 0.081 Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 3/111 (2%) Query: 1956 SVRLEKHATVPSPPTAPLE--IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 S R A PP +P++ I + + W P+ D P+ GY + R V W Sbjct: 507 STRFTVTAARKHPPDSPVDAVIHNKTESSITIQWSPPDSDRPVPIKGYIVESRKVGNKTW 566 Query: 2014 MEVGKVD-VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + + + + + +E +Y RI A N+ G S LE F + P Sbjct: 567 QRCNAGETITSTEITLCSFAEEASYQFRISAMNDFGQSPYLEVPGSFYLEP 617 Score = 38.3 bits (85), Expect = 2.3 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 1/91 (1%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 VG + ++ + G P P + W ++ KL + + + I EL S +Y Sbjct: 23 VGKDATLSCTVVGSPTPLITWERDKLKLTSGGRFKTVEDGDVYRLTIYELTLEDSGQYMC 82 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPE-GPVIM 1675 A N G + VTLKV P+ PV + Sbjct: 83 RAKNNVGEAYAAVTLKVALPAEMPQRAPVFV 113 Score = 37.5 bits (83), Expect = 4.0 Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 V F+C+V ++ WF+ +KP + ++ TLVI + PEDAGT+ C Sbjct: 2027 VTFDCEVSR-TNTEVKWFKDNVELKPGKMVGIH-SLGRKRTLVINKCTPEDAGTYIC 2081 >UniRef50_UPI0000DB7010 Cluster: PREDICTED: similar to CG33519-PB; n=1; Apis mellifera|Rep: PREDICTED: similar to CG33519-PB - Apis mellifera Length = 1306 Score = 162 bits (393), Expect = 1e-37 Identities = 187/795 (23%), Positives = 338/795 (42%), Gaps = 77/795 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPD-IAWLFKGEEIVPDENISVAIESDMHMYC 692 P F K + V+ G + EC L+ + WL + + ++ ++ + + Sbjct: 479 PVFVKTLEGSSVEPGEMAVFECTLLYTDSTTRVQWLKDNKPL--EDRLADRLTASATGKT 536 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLP---IVLKIKTGEKEP------PQVIEPLKS 743 L + NV + G Y A+N EG+++ IV ++ EK+ P + LK Sbjct: 537 FRLTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKD 596 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGDTHSITILKPKK 796 + + + +V G+P P + + K+N VK + + D + + IL+ + Sbjct: 597 TELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVKIVTEQGDKGFYEL-ILEDVQ 655 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 +D G Y+ A+N G A +TV + E L++ E G Sbjct: 656 KQDAGKYSCTAKNKFGETSCEASVTVSD------EKMLYLPE----DFLEPGM------- 698 Query: 857 TRNPVPSITWYRNNEIISPSETITQNF-DGEN-IELVITNVDSEIDSGDYKCVASNSAGK 914 P TW R+ + P E F D E+ + LV +V E D+G Y CVA S G Sbjct: 699 ----EPRFTWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPE-DAGLYTCVAQTSTGN 753 Query: 915 SSHGARVTI---------DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHN 963 S A +T+ D E+ + S E G + +LE Q KW + Sbjct: 754 ISCSAELTVQGAVNQLLKDPERPKLCSEAKHS-EVSAGGSAMLELQIRGYPKPDIKWTKD 812 Query: 964 KKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEF 1019 +EI +G ++ + ++ D GV K++ +T+ + ++ ++ P+ Sbjct: 813 GQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIELIVKSAPKI 872 Query: 1020 IRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGH-IRKLYIR 1077 R+ D + + VEI + A +V W +DG+ IK + N+ E+ G+ KL I+ Sbjct: 873 TRRQTDTTCIVDETLTMTVEIEATPAPEVKWYKDGQEIK-ENNRITIEREGNETYKLTIK 931 Query: 1078 NTSVHDEGEYSCILRDE-SCTAEVTVVEL--PPEIITRLQNQKV-NKGNKATFEIELTKG 1133 N + D G YS + R+E + T E+ +++ PP I L + ++G +E+ Sbjct: 932 NARLDDTGSYSIVARNEVNQTTEIWKLKVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSV 991 Query: 1134 -DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--GNSKCTAILT 1190 ++W++DG + N I++T +G + L+I + +DAG Y E+ + T Sbjct: 992 MPPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKAEITSDHGVVTDQTR 1051 Query: 1191 VEEPSI-NFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWY-KKKSVIEDTEKFTLISD 1247 + I F ++ + + D VEI + WY + E ++F + Sbjct: 1052 IRVKGIPRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEE 1111 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK-LKVEVVEFPPKIVDYEREYRIKRGSDVT 1306 + TLII + + + YTC L + K +V P+++ + RIK G + Sbjct: 1112 EESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRPRLLKKLADQRIKEGDTLK 1171 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIK---KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 L+ + P P +W + + + + K T+ S ++ LT+ V+ +DAGIY++R E Sbjct: 1172 LIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKGSDAGIYEVRAE 1231 Query: 1364 NNCGHADVEMNVTIL 1378 N G + V I+ Sbjct: 1232 NELGFVTSKSKVLIM 1246 Score = 132 bits (319), Expect = 1e-28 Identities = 131/531 (24%), Positives = 222/531 (41%), Gaps = 54/531 (10%) Query: 539 PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 P+ TW R P + F++ + D+++ LV + V PEDAG +TCVA+ + G S + E Sbjct: 700 PRFTWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAE 759 Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L V+ ++ + + P + K V G +LE ++ Sbjct: 760 LTVQGAVNQL--------------------LKDPERPKLCSEAKHSEVSAGGSAMLELQI 799 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P+PDI W G+EIV E + M L I NV G YT+ A N G Sbjct: 800 RGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESM---SLVIKNVTAKDAGVYTIRAKNELG 856 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK- 776 E + I L +K+ P++ E++ ++ ++ P P + W K+ + +K Sbjct: 857 EDTTQIELIVKSA----PKITRRQTDTTCIVDETLTMTVEIEATPAPEVKWYKDGQEIKE 912 Query: 777 --ALPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 + + +G +T+ +TI K ++ D G Y++ A N + +T+ + ++ PP Sbjct: 913 NNRITIEREGNETYKLTI-KNARLDDTGSYSIVARNE--VNQTTEIWKLKV-----LSPP 964 Query: 834 LFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 E + ++G + L V PSI WYR+ E + I +G L I Sbjct: 965 RIRKGLGEPVIIDQGANLVLTVEVDSVMPPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRI 1024 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI---LE 949 N SE D+G YK ++ G + R I V+ + K EG I +E Sbjct: 1025 VNTVSE-DAGFYKAEITSDHGVVTDQTR--IRVKGIPRFKTKMYDVTVNEGTKDIEFKVE 1081 Query: 950 CQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV-GVIKCIVKDQ---- 1004 S WY + EI+ + +E ++ G C +K++ Sbjct: 1082 IDGCPQPSIHWYIDDVEITEKRKEFVRKEEEESCTLIISEAKTELKGRYTCKLKNEFGEV 1141 Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054 ++S+ L+V P ++KL D +KE D L E+ + V W +DG+ Sbjct: 1142 KSSSTLIVNSR-PRLLKKLADQRIKEGDTLKLIFEVAGTPDPQVKWYKDGQ 1191 Score = 131 bits (317), Expect = 2e-28 Identities = 162/703 (23%), Positives = 290/703 (41%), Gaps = 81/703 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKPK-KNKYDFEKRGHIRK 1073 P F++ L+ V+ ++A+ E + T V W +D + ++ + ++ G + Sbjct: 479 PVFVKTLEGSSVEPGEMAVFECTLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKTFR 538 Query: 1074 LYIRNTSVHDEGEYSC-ILRDE---SCTAEVTVVELPPE------------IITRLQNQK 1117 L ++N D G Y + E +CTA++ V +L PE + RL++ + Sbjct: 539 LTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKDTE 598 Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI---DGKK--QKLKIYDCDL 1170 + + F +++ KGD ++++KD I SNH ++ I G K +L + D Sbjct: 599 LMENTYLRFMVKV-KGDPNPEMKFYKDNVLID-SNHPRVKIVTEQGDKGFYELILEDVQK 656 Query: 1171 DDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 DAG+YSC + G + C A +TV + + L LPE L P + Sbjct: 657 QDAGKYSCTAKNKFGETSCEASVTVSDEKM---LYLPEDFLEPGMEPRF----------- 702 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTL--IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV- 1283 TW + + E+F ++ + TL + + +D YTCV + E+ Sbjct: 703 -TWLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAELT 761 Query: 1284 --------VEFP--PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCK 1332 ++ P PK+ + + G L + + +P+P+ +W + + I+ K Sbjct: 762 VQGAVNQLLKDPERPKLCSEAKHSEVSAGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGK 821 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 + D +S SL IK V DAG+Y +R +N G ++ + + P + Sbjct: 822 YKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIELIVKSAPKITRRQTDTTC 881 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYR 1450 E E T + +Y + QEI I+++ + +I+N + + + Sbjct: 882 IVDETLTMTVEIEATPAPEVKWYK-DGQEIKENNRITIEREGNETYKLTIKNARLDDTGS 940 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVP 1509 + A NEV+ +TTE +K+ + P + K L + + + ++ LT V Sbjct: 941 YSIVARNEVN-----QTTEIWKL---KVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSVM 992 Query: 1510 QPKVTWYRDGKKL---KTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P + WYRDG+ + K T E NR YK +DHG V + Sbjct: 993 PPSIKWYRDGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKAEITSDHGVVTDQTRI 1052 Query: 1566 GIQQKPVITISNEDIKQKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITT 1623 ++ P D+ D E+ V I+G P P + WY + ++ E KE+ Sbjct: 1053 RVKGIPRFKTKMYDVTVNEGTKDIEFKVE--IDGCPQPSIHWYIDDVEITEKRKEFVRKE 1110 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +E++ + I E K +YT + N G TL V +P Sbjct: 1111 EEESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRP 1153 Score = 116 bits (279), Expect = 7e-24 Identities = 183/846 (21%), Positives = 329/846 (38%), Gaps = 95/846 (11%) Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-------DVE 926 S S + + + + + T+ E S K AS+ +S R ++ + Sbjct: 418 SSSSKVVEEYSSVSSSQIGTSTYVESSSSAVKMEASSYQAGNSIETRTSMAKIEGGGGIG 477 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVST---KWYHNKKEISGM--DHREIIQEGRX 981 K FVK L+ S E G+ + EC +T ST +W + K + D G+ Sbjct: 478 KPVFVKTLEGS-SVEPGEMAVFECTLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKT 536 Query: 982 XXXXXXXXXXXDVGV-IKCIVKDQETST---MLVVKETIPE------------FIRKLQD 1025 D G+ I + + ST L+V++ PE F+ +L+D Sbjct: 537 FRLTLQNVLESDSGIYIARAMNSEGQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKD 596 Query: 1026 FEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDF-EKRGH--IRKLYIRNTSV 1081 E+ E V++ + ++ + +D +I + ++G +L + + Sbjct: 597 TELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVKIVTEQGDKGFYELILEDVQK 656 Query: 1082 HDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 D G+YSC +++ SC A VTV + E + L + G + F Sbjct: 657 QDAGKYSCTAKNKFGETSCEASVTVSD---EKMLYLPEDFLEPGMEPRFT---------- 703 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL--DDAGEYSC----EVGNSKCTAILTV 1191 W +DG ++ + L + + +DAG Y+C GN C+A LTV Sbjct: 704 -WLRDGKPFDPEERFKVLFKDNEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAELTV 762 Query: 1192 EEPSINFTLRLPE---------FILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEK 1241 + ++N L+ PE V A A L ++I D+ W K I K Sbjct: 763 QG-AVNQLLKDPERPKLCSEAKHSEVSAGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGK 821 Query: 1242 FTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYR 1298 + + D + +L+I+ T D YT + + TT++++ +V+ PKI + + Sbjct: 822 YKYLWEDEESMSLVIKNVTAKDAGVYTIRAKNELGEDTTQIEL-IVKSAPKITRRQTDTT 880 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH-TKPSIDSKSASLTIKKVENTDAGI 1357 +T+ V+ +A P P +W + + IK+ T +++ LTIK D G Sbjct: 881 CIVDETLTMTVEIEATPAPEVKWYKDGQEIKENNRITIEREGNETYKLTIKNARLDDTGS 940 Query: 1358 YKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y + N + +L P G + ID + + E ++ +I +Y Sbjct: 941 YSIVARNEVNQTTEIWKLKVLSPPRIRKGLGEPVIIDQGANLVLTVEVDSVMPPSIKWYR 1000 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 ++ K + I N + + ++A E+ SD T+ ++ Sbjct: 1001 DGEPVVEDNRIKMTKEGNRFVLRIVNTVSEDAGFYKA----EIT-SDHGVVTDQTRI--- 1052 Query: 1477 TKIQS-PTVEKPLKNITT-EPNEDIELTCIFGGVPQPKVTWYRDG-----KKLKTAKATY 1529 +++ P + + ++T E +DIE G PQP + WY D K+ + + Sbjct: 1053 -RVKGIPRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEE 1111 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589 E Y C N+ GEV++S + + +P + D Q+ K GD Sbjct: 1112 EESCTLIISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNSRPRLLKKLAD--QRIKEGDT 1169 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHSSKYTIE 1646 + + G P P+V WYK+G ++ D IT K + + +K S + Y + Sbjct: 1170 LKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKGSDAGIYEVR 1229 Query: 1647 ASNTAG 1652 A N G Sbjct: 1230 AENELG 1235 Score = 63.7 bits (148), Expect = 5e-08 Identities = 111/502 (22%), Positives = 186/502 (37%), Gaps = 47/502 (9%) Query: 1217 TVEIPDETLDVTWYKKKSVIED--TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 T+ D T V W K +ED ++ T + K L ++ E D Y ++++ Sbjct: 501 TLLYTDSTTRVQWLKDNKPLEDRLADRLTASATGKTFRLTLQNVLESDSGIYIARAMNSE 560 Query: 1275 --STTKLKVEVVEFPPKIVDYEREYR----IKRGSDVTLLVD-YQAFP-----QPNDEW- 1321 ST ++ V + P+ E + R D L+ + Y F PN E Sbjct: 561 GQSTCTAQLIVQQLTPEEKKARAEANAPIFLVRLKDTELMENTYLRFMVKVKGDPNPEMK 620 Query: 1322 IVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 ++ H + I D L ++ V+ DAG Y +N G E +VT Sbjct: 621 FYKDNVLIDSNHPRVKIVTEQGDKGFYELILEDVQKQDAGKYSCTAKNKFGETSCEASVT 680 Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 + D+ + LE W + + V+ DT + Sbjct: 681 VSDEKMLYLPEDFLE-PGMEPRFTWLRDGKPFDPEERFKVLFKDNEDTLALV-------- 731 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKETKI-QSPTVEKPLKNITTE 1494 Q++K + + A +IS ++E T V + K + P + K+ Sbjct: 732 ---FQHVKPEDAGLYTCVAQTSTGNISCSAELTVQGAVNQLLKDPERPKLCSEAKHSEVS 788 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATY----ENRXXXXXXXXXXXXXXXYK 1549 L G P+P + W +DG+++ K Y E Y Sbjct: 789 AGGSAMLELQIRGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYT 848 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL-VTAVIEGIPPPEVIWYK 1608 A N+ GE T + ++ P IT D + DE L +T IE P PEV WYK Sbjct: 849 IRAKNELGEDTTQIELIVKSAPKITRRQTDTTC---IVDETLTMTVEIEATPAPEVKWYK 905 Query: 1609 NGNKLENDKEYNITTK-EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +G +++ + I + +T + IK + + Y+I A N ++ LKV P Sbjct: 906 DGQEIKENNRITIEREGNETYKLTIKNARLDDTGSYSIVARNEVNQTTEIWKLKVLSPPR 965 Query: 1668 KPEG---PVIMREISRESVTIE 1686 +G PVI+ + + +T+E Sbjct: 966 IRKGLGEPVIIDQGANLVLTVE 987 Score = 60.9 bits (141), Expect = 4e-07 Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 16/201 (7%) Query: 629 LEGIPPTFSKKPKAQYVDEGS-DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++GIP F K V+EG+ DI + + P+P I W EI E + + Sbjct: 1054 VKGIP-RFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEIT--EKRKEFVRKE 1110 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 C+++ I+ K +G YT N GE L + + P++++ L ++ Sbjct: 1111 EEESCTLI-ISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNS----RPRLLKKLADQRIK 1165 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG---DTHSITILKPKKVKDEG 801 +G+++ L +V G P P + W K+ + V A + D + + +T+ K D G Sbjct: 1166 EGDTLKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYDLTVTLVKG-SDAG 1224 Query: 802 VYTLKAENSEGIAETSAVITV 822 +Y ++AEN G + + + + Sbjct: 1225 IYEVRAENELGFVTSKSKVLI 1245 Score = 58.4 bits (135), Expect = 2e-06 Identities = 27/79 (34%), Positives = 44/79 (55%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + E Q+ GYP+P I W + I ++ ++D+ +LVI+ V +DAG +T Sbjct: 790 GGSAMLELQIRGYPKPDIKWTKDGQEIVAGGKYKYLWEDEESMSLVIKNVTAKDAGVYTI 849 Query: 584 VAKNAAGFASSTTELIVEA 602 AKN G ++ ELIV++ Sbjct: 850 RAKNELGEDTTQIELIVKS 868 Score = 50.0 bits (114), Expect = 7e-04 Identities = 26/105 (24%), Positives = 52/105 (49%), Gaps = 3/105 (2%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII---KPSQD 555 E+ + ++ APIF+ +L+ + + ++F +V+G P P++ +++ +I P Sbjct: 577 EEKKARAEANAPIFLVRLKDTELMENTYLRFMVKVKGDPNPEMKFYKDNVLIDSNHPRVK 636 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 D L++ +V +DAG ++C AKN G S + V Sbjct: 637 IVTEQGDKGFYELILEDVQKQDAGKYSCTAKNKFGETSCEASVTV 681 Score = 48.0 bits (109), Expect = 0.003 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%) Query: 510 PIFVEKLRPKHTPDGST-VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P F K+ +G+ ++F+ +++G P+P I W+ I + + +++ TL Sbjct: 1058 PRFKTKMYDVTVNEGTKDIEFKVEIDGCPQPSIHWYIDDVEITEKRKEFVRKEEEESCTL 1117 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 +I E E G +TC KN G S++ LIV + Sbjct: 1118 IISEAKTELKGRYTCKLKNEFGEVKSSSTLIVNS 1151 Score = 41.9 bits (94), Expect = 0.19 Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-- 567 P ++KL + +G T++ +V G P PQ+ W++ + ++ D Sbjct: 1153 PRLLKKLADQRIKEGDTLKLIFEVAGTPDPQVKWYKDGQEVSADARIKITRDSKRQENYD 1212 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + V DAG + A+N GF +S +++++ Sbjct: 1213 LTVTLVKGSDAGIYEVRAENELGFVTSKSKVLI 1245 Score = 37.5 bits (83), Expect = 4.0 Identities = 17/78 (21%), Positives = 37/78 (47%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 T+ ++E P P++ W++ IK + + + + L I+ +D G+++ VA Sbjct: 886 TLTMTVEIEATPAPEVKWYKDGQEIKENNRITIEREGNETYKLTIKNARLDDTGSYSIVA 945 Query: 586 KNAAGFASSTTELIVEAP 603 +N + +L V +P Sbjct: 946 RNEVNQTTEIWKLKVLSP 963 >UniRef50_UPI0000E472F4 Cluster: PREDICTED: similar to SEC14 and spectrin domains 1; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SEC14 and spectrin domains 1 - Strongylocentrotus purpuratus Length = 3464 Score = 159 bits (387), Expect = 6e-37 Identities = 117/466 (25%), Positives = 203/466 (43%), Gaps = 19/466 (4%) Query: 465 EKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDG 524 EK + + E+ TQ +K+ E P E + AP F K+R G Sbjct: 2377 EKSTKSIKLVQPESPITQ-TRKEPVEAFLTFPAPEPEPPKPVGYAPYFTRKIRDNLVKQG 2435 Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 Q +C V+G P P++ WF+ ++ S + ++ D + L PE AG ++ Sbjct: 2436 RATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGICALSFYNTQPEAAGVYSIK 2495 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 A N G A EL V+A + V P F + P + Sbjct: 2496 AFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKLTH----NATMPKFIEIPGDKN 2551 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V+EG ++LE + A P+P++ W G + V E + ++ H L I Sbjct: 2552 VEEGKPLILEVTVDAYPQPNVVWSKDGIK-VKGEPYILKVDKKTH----TLIIPEADLED 2606 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 EG + A N G A I +K+ E EPP + PL + ++G + G+P P Sbjct: 2607 EGIFICTATNPAGRAECIIQVKVNEAE-EPPVFLTPLVNAQAKKGTPFAFECVLKGDPVP 2665 Query: 765 TITWCKNNKPVKA----LPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818 + W KNNKPVK K + +T + L+ +V +D Y+ +A N G AET+ Sbjct: 2666 VVEWLKNNKPVKEENPDYNLKRNTET-GVCRLEIDEVFPEDAARYSCRATNEAGKAETTC 2724 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 +++V +++ P+ I+ +++T++E I+L ++ S+ W++ +E + + Sbjct: 2725 MLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGE 2784 Query: 879 ITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 FD E + ++ N D G Y C A+N+ G+++ A + + Sbjct: 2785 FLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIV 2830 Score = 122 bits (295), Expect = 8e-26 Identities = 173/818 (21%), Positives = 306/818 (37%), Gaps = 99/818 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E K+ +G + E V+ YP+P + W + IK + + D TL+ Sbjct: 2541 PKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDG--IKVKGEPYILKVDKKTHTLI 2598 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I E ED G F C A N AG A E I++ +++ Sbjct: 2599 IPEADLEDEGIFICTATNPAGRA----ECIIQVKVNEAEE-------------------- 2634 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 PP F +G+ EC L P P + WL K + V +EN ++ + Sbjct: 2635 ---PPVFLTPLVNAQAKKGTPFAFECVLKGDPVPVVEWL-KNNKPVKEENPDYNLKRNTE 2690 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK---TGEKEPPQVIEPLKSMIV 746 L+I V Y+ A N G+A +L + + P +I + M + Sbjct: 2691 TGVCRLEIDEVFPEDAARYSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTL 2750 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802 ++G+ + L+ Q+ G ++ W K ++ + + L T D + ++ + +DEGV Sbjct: 2751 QEGDPIRLTCQIGGELPLSVNWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGV 2810 Query: 803 YTLKAENSEGIAETSA---VITVEEPTEENA-------EPPLFINRFQEITVKEKGTIKL 852 YT +A N+ G +SA V+T + + A E +++ + +TV+E KL Sbjct: 2811 YTCQATNAWGRTASSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKL 2870 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 V + WY+ E + F N+ + N DSG Y C +N+ Sbjct: 2871 ACVVDGIAPITAQWYKGEEALDEGYEYVMKFQS-NMATLHVNESFPEDSGMYTCRVTNAI 2929 Query: 913 GKSSHGARVTIDVEKVTFVKHLQ------KSYETEEGKTVILECQTSHT--VSTKWYHNK 964 G A+VT+ + +Q S E G+ + L + S + W+H+ Sbjct: 2930 GSDESSAQVTVLEDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDD 2989 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPE 1018 + + ++++E D G +++ T LV+KE PE Sbjct: 2990 RPLRPDGRIKVVKEDTTYTMQISRSEPDDTGKYTIRAENESGHESSSTDYKLVIKEAKPE 3049 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 + +K +EI DVV + P K + F ++ + Sbjct: 3050 YAGTYTVVAENDKGQESTSIEI-----DVVPPETQMEVVPVKAEPAF---APLQSRFFTQ 3101 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPP-EIITRLQNQKVNKGNKATFEIELTKGDALV 1137 + R +S ++ V E P EI R+ Q + + Sbjct: 3102 PDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPR----------------I 3145 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVE- 1192 W+KD I +++ +L + + L+D G Y C+ G T +TV Sbjct: 3146 TWYKDDEPINGKPQYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNV 3205 Query: 1193 ----EPSINFTLRLPEF--ILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLI 1245 P+ + +F + +P L I + VTW + I +TE+ +I Sbjct: 3206 NAALTPAPHVVPLQTQFSHLDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEII 3265 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 + TL+I+ D +YT V + + T + + + Sbjct: 3266 KEETVHTLVIKNPRPDAGGKYTVVAENERGTETVNIVI 3303 Score = 113 bits (272), Expect = 5e-23 Identities = 236/1116 (21%), Positives = 409/1116 (36%), Gaps = 156/1116 (13%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P F++K + V +G L+C + P P++ W G + N+ V E Sbjct: 2418 GYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRV--ECGDAG 2475 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEAS---------------LPI-VLKIKTGEKE- 733 C+ L N + G Y++ A N GEA LP V K+ TG + Sbjct: 2476 ICA-LSFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKL 2534 Query: 734 -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDT 786 P+ IE V +G+ +IL V P+P + W K+ VK P K D T Sbjct: 2535 THNATMPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPYILKVDKKT 2594 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 H++ I+ ++DEG++ A N G AE +I V+ E EPP+F+ K+ Sbjct: 2595 HTL-IIPEADLEDEGIFICTATNPAGRAE--CIIQVK--VNEAEEPPVFLTPLVNAQAKK 2649 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEII---SPSETITQNFDGENIELVITNVDSEIDSGD 903 + +PVP + W +NN+ + +P + +N + L I V E D+ Sbjct: 2650 GTPFAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPE-DAAR 2708 Query: 904 YKCVASNSAGKSSHGARVTI------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTV- 956 Y C A+N AGK+ +++ D+ + H + +EG + L CQ + Sbjct: 2709 YSCRATNEAGKAETTCMLSVMGLDDDDLRAPVIISH-PEDMTLQEGDPIRLTCQIGGELP 2767 Query: 957 -STKWYHNKKEISGMDHR-EII-----QEGRXXXXXXXXXXXXDVGVIKCIVKDQ----E 1005 S W+ KE +D E + QEG D GV C + Sbjct: 2768 LSVNWF---KEDEALDEAGEFLMTFDDQEG-LAVLKVNESFAEDEGVYTCQATNAWGRTA 2823 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE----VEINS----ETADVV--------- 1048 +S L+V + E D K + IL V + + A VV Sbjct: 2824 SSANLIVVTAVDEIDAAAADVSPKHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQ 2883 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-----ILRDESCTAEVTVV 1103 W + GE + +Y + + ++ L++ + D G Y+C I DES +A+VTV+ Sbjct: 2884 WYK-GEEALDEGYEYVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDES-SAQVTVL 2941 Query: 1104 ELPPEIITRLQNQKVNKGN---------KATFEIELTKGDALVRWFKDGSEIQFSNHIQL 1154 E +Q K+ + K F++ + V W D ++ I++ Sbjct: 2942 EDSSPTAPWIQPLKLESNSLEITVGQPIKLAFKVS-GNPEPTVTWHHDDRPLRPDGRIKV 3000 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 + ++I + DD G+Y+ N E S ++ L + E P Sbjct: 3001 VKEDTTYTMQISRSEPDDTGKYTIRAENESGH-----ESSSTDYKLVIKE--AKPEYAGT 3053 Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDT--EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 Y V D+ + T + V +T E + ++ L R T+ D Sbjct: 3054 YTVVAENDKGQESTSIEIDVVPPETQMEVVPVKAEPAFAPLQSRFFTQPDA--------- 3104 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + V PP+ ++ + G + + + P P W + + I Sbjct: 3105 ------MPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKP 3158 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 + S A L +++ D G Y + N G +T+ + P+++ + Sbjct: 3159 QYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPHVVPL 3218 Query: 1393 DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 + ++ D P G +++ + Q W+ Q ++ ++T + Sbjct: 3219 QTQFSHL--DIP--VGQPIRLHFRIRGQPPPKVTWL--------QNDVEIVETEEVEIIK 3266 Query: 1453 AYAVNEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP-Q 1510 V+ + I + + Y V+ E + + TV NI + + F P Q Sbjct: 3267 EETVHTLVIKNPRPDAGGKYTVVAENERGTETV-----NIVINVSG---VQWFFNNTPIQ 3318 Query: 1511 P--KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI- 1567 P +V + RDG Y Y+C A + V T C + + Sbjct: 3319 PSDRVEFVRDGD-------VY----YLVIKRPTSGDAGLYQCRAETEVSVVTTECTIMVN 3367 Query: 1568 -QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 +Q P E + G + + G P P V W K+ + T+ Sbjct: 3368 DKQSPDFIAPLESVVASE--GSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGD 3425 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ I +++ S + Y I +N G S TL + Sbjct: 3426 RQILMIIQVRPSDAGNYRITLTNDFGVSVSSATLLI 3461 Score = 91.1 bits (216), Expect = 3e-16 Identities = 130/633 (20%), Positives = 240/633 (37%), Gaps = 73/633 (11%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTI-DGKKQKL 1163 P ++++ V +G + + KGD V WFKDG ++ SN++++ D L Sbjct: 2421 PYFTRKIRDNLVKQGRATQLDC-VVKGDPAPEVEWFKDGVPVRTSNNLRVECGDAGICAL 2479 Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTL------------------R 1201 Y+ + AG YS + +G + C A L V+ F L Sbjct: 2480 SFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHIKLTHNAT 2539 Query: 1202 LPEFILVPANTDAY----LTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 +P+FI +P + + L +E+ + +V W K ++ E + L D K TLI Sbjct: 2540 MPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKG-EPYILKVDKKTHTLI 2598 Query: 1255 IRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 I + +D+ + C + A+ ++KV E PP + + K+G+ Sbjct: 2599 IPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTPFAFECV 2658 Query: 1311 YQAFPQPNDEWIVNSKIIKKCK---HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + P P EW+ N+K +K+ + K + ++ L I +V DA Y R N G Sbjct: 2659 LKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCRATNEAG 2718 Query: 1368 HADVE--MNVTILDKP--------SPPGKPNILEID----------SSSINICWDEPENT 1407 A+ ++V LD S P + E D +++ W + E+ Sbjct: 2719 KAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQEGDPIRLTCQIGGELPLSVNWFK-EDE 2777 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 +++ + + + + V + + +++ A + N + ++ E Sbjct: 2778 ALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIVVTAVDEI 2837 Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----K 1523 + K ++ + L+N+T + +L C+ G+ WY+ + L + Sbjct: 2838 DAAAADVSP-KHEAACILSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEEALDEGYE 2896 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT------ISN 1577 N Y C N G E+S V + + T + Sbjct: 2897 YVMKFQSNMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTVLEDSSPTAPWIQPLKL 2956 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 E + VG + + G P P V W+ + L D + ++ T ++I + Sbjct: 2957 ESNSLEITVGQPIKLAFKVSGNPEPTVTWHHDDRPLRPDGRIKVVKEDTTYTMQISRSEP 3016 Query: 1638 SHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 + KYTI A N +G S K+ K +KPE Sbjct: 3017 DDTGKYTIRAENESGHESSSTDYKLVIKEAKPE 3049 Score = 78.6 bits (185), Expect = 2e-12 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 26/221 (11%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +M P F +L+ +G ++ +V G P P+ITW++ I ++M + ++VA Sbjct: 3111 AMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITWYKDDEPINGKPQYEMSF-VESVA 3169 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 L +RE F ED G + C A N AG ++T ++ V A Sbjct: 3170 RLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNV-----------------NAALTPA 3212 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 + + FS + G I L R+ P P + WL EIV E + + E Sbjct: 3213 PHVVPLQTQFSHLD----IPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEE 3268 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 +H L I N + G YTVVA N G ++ IV+ + Sbjct: 3269 TVH----TLVIKNPRPDAGGKYTVVAENERGTETVNIVINV 3305 Score = 74.5 bits (175), Expect = 3e-11 Identities = 74/273 (27%), Positives = 118/273 (43%), Gaps = 26/273 (9%) Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG-----SEMTVXXXXXXXXX 622 LVI+E PE AGT+T VA+N G S++ E+ V P + +E Sbjct: 3041 LVIKEAKPEYAGTYTVVAENDKGQESTSIEIDVVPPETQMEVVPVKAEPAFAPLQSRFFT 3100 Query: 623 XXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 A + G +PP F + K V EG I + R+ P P I W +K DE I Sbjct: 3101 QPDAMPVMGAAMPPRFQSRLKDIEVSEGEPIEIAIRVTGQPAPRITW-YK-----DDEPI 3154 Query: 681 SVAIESDMHMYCSVLKITNVKKF--QEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQ 736 + + +M SV ++ + F EG Y A N G+ + I + + P Sbjct: 3155 NGKPQYEMSFVESVARLDVREAFLEDEGRYVCKATNPAGQDTTTCQITVNVNAALTPAPH 3214 Query: 737 VIEPLKSMI----VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789 V+ PL++ + G+ + L ++ G P P +TW +N+ + + + + H++ Sbjct: 3215 VV-PLQTQFSHLDIPVGQPIRLHFRIRGQPPPKVTWLQNDVEIVETEEVEIIKEETVHTL 3273 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 I P+ G YT+ AEN G + VI V Sbjct: 3274 VIKNPRP-DAGGKYTVVAENERGTETVNIVINV 3305 Score = 67.3 bits (157), Expect = 4e-09 Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 11/186 (5%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVK 798 K +V + E + +V N + W NN P++ + DGD + + I +P Sbjct: 3285 KYTVVAENERGTETVNIVINVSG-VQWFFNNTPIQPSDRVEFVRDGDVYYLVIKRPTS-G 3342 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G+Y +AE + T I V + + P FI + + E TI+L R++ Sbjct: 3343 DAGLYQCRAETEVSVVTTECTIMVNDK-----QSPDFIAPLESVVASEGSTIRLECRMSG 3397 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 +P P++ W ++ I+ + + +G+ L+I V D+G+Y+ +N G S Sbjct: 3398 SPAPTVKWTKDERSITETSRVRFLTEGDRQILMIIQVRPS-DAGNYRITLTNDFGVSVSS 3456 Query: 919 ARVTID 924 A + ID Sbjct: 3457 ATLLID 3462 Score = 64.9 bits (151), Expect = 2e-08 Identities = 91/420 (21%), Positives = 158/420 (37%), Gaps = 46/420 (10%) Query: 1287 PPKIVDYE-------REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI- 1338 PPK V Y R+ +K+G L + P P EW + ++ + + Sbjct: 2413 PPKPVGYAPYFTRKIRDNLVKQGRATQLDCVVKGDPAPEVEWFKDGVPVRTSNNLRVECG 2472 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEMNVT------ILDKPSPPGKPNIL 1390 D+ +L+ + AG+Y ++ N G A E++V +L K P + Sbjct: 2473 DAGICALSFYNTQPEAAGVYSIKAFNVIGEAVCKAELHVQAVQEEFVLPKEVPKVSTGHI 2532 Query: 1391 EIDSSS-----INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL-- 1443 ++ ++ I I D+ G I+ V+ W K + I + Sbjct: 2533 KLTHNATMPKFIEIPGDKNVEEGKPLILEVTVDAYPQPNVVWSKDGIKVKGEPYILKVDK 2592 Query: 1444 KTNSSYRFRAYAVNE-VDISDASETTEYYKVIKETKI----QSPTVEKPLKNITTEPNED 1498 KT++ A +E + I A+ + I + K+ + P PL N + Sbjct: 2593 KTHTLIIPEADLEDEGIFICTATNPAGRAECIIQVKVNEAEEPPVFLTPLVNAQAKKGTP 2652 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX-------XXXXXXXXXXYKCI 1551 C+ G P P V W ++ K +K Y + Y C Sbjct: 2653 FAFECVLKGDPVPVVEWLKNNKPVKEENPDYNLKRNTETGVCRLEIDEVFPEDAARYSCR 2712 Query: 1552 AFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 A N+ G+ ET+C++ + + PVI ED+ + GD +T I G P V Sbjct: 2713 ATNEAGKAETTCMLSVMGLDDDDLRAPVIISHPEDMTLQE--GDPIRLTCQIGGELPLSV 2770 Query: 1605 IWYKNGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 W+K L+ E+ +T +E +V+++ E YT +A+N G ++ L V Sbjct: 2771 NWFKEDEALDEAGEFLMTFDDQEGLAVLKVNESFAEDEGVYTCQATNAWGRTASSANLIV 2830 Score = 59.7 bits (138), Expect = 9e-07 Identities = 36/170 (21%), Positives = 76/170 (44%), Gaps = 12/170 (7%) Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 + I + W F I P + + + D++ +K+ G + E Sbjct: 3301 IVINVSGVQWFFNNTPIQPSDRVEFVRDGDVYYLV-------IKRPTSGDAGLYQCRAET 3353 Query: 718 EASLPIV-LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV- 775 E S+ I +K+ P I PL+S++ +G ++ L ++ G+P PT+ W K+ + + Sbjct: 3354 EVSVVTTECTIMVNDKQSPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSIT 3413 Query: 776 --KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 + ++GD + I++ + D G Y + N G++ +SA + ++ Sbjct: 3414 ETSRVRFLTEGDRQILMIIQVRP-SDAGNYRITLTNDFGVSVSSATLLID 3462 Score = 58.0 bits (134), Expect = 3e-06 Identities = 58/243 (23%), Positives = 93/243 (38%), Gaps = 28/243 (11%) Query: 492 IDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 +D++ S + A I + KL +G+ + C V+G W++ + Sbjct: 2834 VDEIDAAAADVSPKHEAACI-LSKLENVTVQEGAPFKLACVVDGIAPITAQWYKGEEALD 2892 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 ++ M + N+ATL + E FPED+G +TC NA G S+ ++ V L D S Sbjct: 2893 EGYEYVMKFQS-NMATLHVNESFPEDSGMYTCRVTNAIGSDESSAQVTV---LED--SSP 2946 Query: 612 TVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671 T +I G P I L ++ PEP + W Sbjct: 2947 TAPWIQPLKLESNSLEITVGQP-----------------IKLAFKVSGNPEPTVTWHHDD 2989 Query: 672 EEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 + PD I V E + ++I+ + G YT+ A N G S K+ E Sbjct: 2990 RPLRPDGRIKVVKEDTTY----TMQISRSEPDDTGKYTIRAENESGHESSSTDYKLVIKE 3045 Query: 732 KEP 734 +P Sbjct: 3046 AKP 3048 Score = 52.4 bits (120), Expect = 1e-04 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 1/94 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 +P F+ L +GST++ EC++ G P P + W + I + + + D + Sbjct: 3371 SPDFIAPLESVVASEGSTIRLECRMSGSPAPTVKWTKDERSITETSRVRFLTEGDRQILM 3430 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 +I +V P DAG + N G + S+ L+++A Sbjct: 3431 II-QVRPSDAGNYRITLTNDFGVSVSSATLLIDA 3463 >UniRef50_O75147 Cluster: Obscurin-like protein 1 precursor; n=35; Eutheria|Rep: Obscurin-like protein 1 precursor - Homo sapiens (Human) Length = 1401 Score = 159 bits (385), Expect = 1e-36 Identities = 260/1234 (21%), Positives = 475/1234 (38%), Gaps = 116/1234 (9%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 K +S +Q P F+ RP G+ + +C V G P P + W + + S+ + Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLS-F 60 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA-SSTTELIVEAPLSDHGSEMTVXXXXX 618 D L++ P DAG + C A+NAAG A ++ ++E P SD E+ Sbjct: 61 PADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASD--PELQPAERPL 118 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG---EEIV 675 EG P F P++Q+V G++++L CR +PEP + W G +E+ Sbjct: 119 PSPGSG-----EG-APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVW 172 Query: 676 PDENISV--AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 + ++ D L+I + G Y A N G A +L++ + Sbjct: 173 DSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPES 232 Query: 734 PP--------QVIEPL----KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781 PP V+EPL K+ V +G+ V+G P P I W +P+ LP + Sbjct: 233 PPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPL--LPDR 290 Query: 782 -----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836 D D + + + KD G+Y A NS G ++ + V+EP P Sbjct: 291 RRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRP---- 346 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896 Q++ +E G L +V + +P+ W+R ++ + P Q +G L+I + Sbjct: 347 --LQDVEGREHGIAVLECKVPNSRIPT-AWFREDQRLLPCRKYEQIEEGTVRRLIIHRLK 403 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT- 955 ++ D G Y C G+ A VT+ K +K L + + EG+ +L +T Sbjct: 404 AD-DDGIYLC---EMRGRVRTVANVTV---KGPILKRLPRKLDVLEGENAVLLVETLEAG 456 Query: 956 VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK-- 1013 V +W + +E+ + G D G + + + T+T+L VK Sbjct: 457 VEGRWSRDGEELPVICQS---SSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCV 513 Query: 1014 ETIPEFIRKLQDFEVKEKDVAIL---EVEINSETADVV-WERDGEIIKPKKNKYDFEKRG 1069 + P L + K+ +L E ET + ER + + EK G Sbjct: 514 KHSPPGPPILAEMFKGHKNTVLLTWKPPEPAPETPFIYRLERQEVGSEDWIQCFSIEKAG 573 Query: 1070 HIRKLYIRNTSVHDEGEYS---CILRDESCTAEVTV---VELPP--EIITRLQNQKVNKG 1121 + + V EG+Y C + + V L P ++ L++ +V G Sbjct: 574 AVE---VPGDCVPSEGDYRFRICTVSGHGRSPHVVFHGSAHLVPTARLVAGLEDVQVYDG 630 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSN----------HIQLTIDGKKQKLKIYDCDLD 1171 A F ++L+ WF +G E++ + ++ G + +L ++ Sbjct: 631 EDAVFSLDLST-IIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQ 689 Query: 1172 DAGE---YSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD-AYLTVEIPDETLDV 1227 D+G +SC + +A LT++E ++ + L ++ LT E+ Sbjct: 690 DSGALVGFSCP--GVQDSAALTIQESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPA 747 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287 TWYK +E++E + D +K LI+ + D E+ C + V V + P Sbjct: 748 TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAF--FGVTVQDPP 805 Query: 1288 PKIVDYEREYRIKRG--SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 IVD RE+ S+ +L W + + +++ + L Sbjct: 806 VHIVD-PREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRL 864 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSINICW 1401 + + +D G ++ + C + VTI D S P GK + + + + Sbjct: 865 VLPATQPSDGGEFQCVAGDECAY----FTVTITDVSSWIVYPSGKVYVAAVRLERVVLTC 920 Query: 1402 DEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 + + + + +E +++ + K T + + ++ S + + E+D Sbjct: 921 ELCRPWAE---VRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEY----LCEID 973 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 AS T + +I P E L +T E + L C P V WY+DG Sbjct: 974 DESASFTVTVTE--PPVRIIYPRDEVTLIAVTL---ECVVLMCELSREDAP-VRWYKDGL 1027 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 +++ ++A R D G+ V + + PV ++ E Sbjct: 1028 EVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALETT 1087 Query: 1581 KQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 V G+ +++ + P V+W NG ++ + + + V+ I+ + Sbjct: 1088 PSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPA 1146 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 H+ YT ++ G S+ T++V + P + P Sbjct: 1147 HAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAP 1180 Score = 136 bits (329), Expect = 6e-30 Identities = 133/533 (24%), Positives = 225/533 (42%), Gaps = 29/533 (5%) Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 IL K +D G L + G+ + SA +T++E P ++ +T + Sbjct: 682 ILHAVKHQDSGA--LVGFSCPGVQD-SAALTIQESPVHILSPQDKVS----LTFTTSERV 734 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 L ++R P+ TWY++ + + SE + DG L++ + DSG+++C Sbjct: 735 VLTCELSRVDFPA-TWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQ-DSGEFEC---R 789 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSY-ETEEGKTVILECQTSHT-VSTKWYHNKKEIS 968 + G S+ VT+ V V + + + V+L C+ +WY + +E+ Sbjct: 790 TEGVSAFFG-VTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVE 848 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQD 1025 D + EG D G +C+ D+ T T+ V I K+ Sbjct: 849 ESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYV 908 Query: 1026 FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 V+ + V +L E+ A+V W +DGE + +K +R+L + + D G Sbjct: 909 AAVRLERV-VLTCELCRPWAEVRWTKDGEEVVESPALL-LQKEDTVRRLVLPAVQLEDSG 966 Query: 1086 EYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI--ELTKGDALVRWFKDG 1143 EY C + DES + VTV E P II + + EL++ DA VRW+KDG Sbjct: 967 EYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDG 1026 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL--R 1201 E++ S + L DG + +L + +D GE+ C+ G+ +TV EP + F Sbjct: 1027 LEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALET 1086 Query: 1202 LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 P + V L+ E+ V W +++ E L ++ +R L I+ Sbjct: 1087 TPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPA 1146 Query: 1262 DQCEYTCVLLDAKSTTKLK--VEVVEFPPKIVDYE-REYRIKR--GSDVTLLV 1309 YTC A L V+V E P ++V E + R++ G D+ L+V Sbjct: 1147 HAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVV 1199 Score = 118 bits (284), Expect = 2e-24 Identities = 129/519 (24%), Positives = 212/519 (40%), Gaps = 59/519 (11%) Query: 725 LKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPT 780 +K +G++ PP + + + V G L V+G P P + W K + + A L Sbjct: 1 MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSF 60 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE--------- 831 +DG H + +L D GVY +A N+ G A +A +TV EP + E Sbjct: 61 PADGAEHGL-LLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLP 119 Query: 832 -------PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETIT 880 P+F+ + V + L R P P++ W ++ +E+ S Sbjct: 120 SPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFAL 179 Query: 881 QNF---DGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTI-----------DV 925 Q DG L + + + + DSG Y C A N+ G + GA + + D Sbjct: 180 QPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDE 239 Query: 926 EKVTFVKHLQ---KSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGR 980 V+ L+ K++ EGK C +W+ + + D R ++ R Sbjct: 240 APAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLP-DRRRLMYRDR 298 Query: 981 XXXXXXXXXX--XXDVGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDVA 1034 D G+ C ++ T+ L VKE F R LQD E +E +A Sbjct: 299 DGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIA 358 Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 +LE ++ + W R+ + + P + KY+ + G +R+L I D+G Y C +R Sbjct: 359 VLECKVPNSRIPTAWFREDQRLLPCR-KYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGR 417 Query: 1095 SCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQ 1153 T V+ P I+ RL + V +G A +E + RW +DG E+ I Sbjct: 418 VRTVANVTVKGP--ILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPV---IC 472 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 + G L + +DAGE + +GNS+ T +L V+ Sbjct: 473 QSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVK 511 Score = 111 bits (266), Expect = 3e-22 Identities = 139/620 (22%), Positives = 240/620 (38%), Gaps = 41/620 (6%) Query: 729 TGEKEPPQVIEPLK--SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSD 783 T ++ P ++ P S+ E V+L+ ++ P TW K+ + V+ L K D Sbjct: 709 TIQESPVHILSPQDKVSLTFTTSERVVLTCELSRVDFPA-TWYKDGQKVEESELLVVKMD 767 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT 843 G H + IL KV+D G + + +EG++ V TV++P +P + F Sbjct: 768 GRKHRL-ILPEAKVQDSGEFECR---TEGVSAFFGV-TVQDPPVHIVDPREHV--FVHAI 820 Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 E + L V R P + WY++ + + S+ + +G + LV+ D G+ Sbjct: 821 TSE--CVMLACEVDREDAP-VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPS-DGGE 876 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG-KTVILECQTSHT-VSTKWY 961 ++CVA + + VTI V K Y + V+L C+ +W Sbjct: 877 FQCVAGDECAYFT----VTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWT 932 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR 1021 + +E+ + +E D G C + D+ S + V E I Sbjct: 933 KDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIY 992 Query: 1022 KLQDFEV--KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 + + + +L E++ E A V W +DG ++ + E+ G +L + Sbjct: 993 PRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVE-ESEALVLERDGPRCRLVLPAA 1051 Query: 1080 SVHDEGEYSCILRDESCTAEVTVVELPPEII---TRLQNQKVNKGNKATFEIELTKGDAL 1136 D GE+ C D+S VTV E P + + T V G EL++ A Sbjct: 1052 QPEDGGEFVCDAGDDSAFFTVTVTEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP 1111 Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT----VE 1192 V W +G +Q ++L +G ++ L I AG Y+C+ G + L+ V Sbjct: 1112 VVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVA 1171 Query: 1193 EPSINFTLRLPEFILVPANT--DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 EP + V + D L V + V WYK + + L + Sbjct: 1172 EPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGAR 1231 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP--PKIVDYEREYRIKRGSDVTLL 1308 + L ++ D EY C DA +++ + VE P K+V + G D T Sbjct: 1232 QVLRVQGARSGDAGEYLC---DAPQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFR 1288 Query: 1309 VDYQAFPQPNDEWIVNSKII 1328 + P + W+ N ++ Sbjct: 1289 CEVSP-PDADVTWLRNGAVV 1307 Score = 75.4 bits (177), Expect = 2e-11 Identities = 128/619 (20%), Positives = 229/619 (36%), Gaps = 51/619 (8%) Query: 1118 VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGE 1175 VN+G A F + K + + W +G + + D LK+ C D G Sbjct: 257 VNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGL 316 Query: 1176 YSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 Y C NS + L V+EP + FT L + + + A L ++P+ + W++ Sbjct: 317 YVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQD-VEGREHGIAVLECKVPNSRIPTAWFR 375 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 + + K+ I + R LII + DD Y C + + + V P + Sbjct: 376 EDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLC---EMRGRVRTVANVTVKGPILK 432 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 R+ + G + LLV+ W S+ ++ S +L + V Sbjct: 433 RLPRKLDVLEGENAVLLVE-TLEAGVEGRW---SRDGEELPVICQSSSGHMHALVLPGVT 488 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTG 1408 DAG L N+ + V + K SPPG P + E+ +++ + W PE Sbjct: 489 REDAGEVTFSLGNS--RTTTLLRVKCV-KHSPPGPPILAEMFKGHKNTVLLTWKPPEPAP 545 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITK---TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + IY +E QE+ + +WI +I K + + + YRFR V S Sbjct: 546 ETPFIYR-LERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGDYRFRICTV-----SGHG 599 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + + + + L+++ ED + + Q TW+ +G++LK+ Sbjct: 600 RSPHVVFHGSAHLVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQG--TWFLNGEELKSN 657 Query: 1526 KATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGE--------VETSCVVGIQQKPVIT 1574 + + + D G V+ S + IQ+ PV Sbjct: 658 EPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHI 717 Query: 1575 ISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 +S +D + + ++T + + P WYK+G K+E + + + + + Sbjct: 718 LSPQDKVSLTFTTSERVVLTCELSRVDFP-ATWYKDGQKVEESELLVVKMDGRKHRLILP 776 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVIMREISRESVTIEWKPP 1690 E K S ++ T G S+ + V D P P V + I+ E V + + Sbjct: 777 EAKVQDSGEF---ECRTEGVSAF-FGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVD 832 Query: 1691 LDDGGLELTKYAIEKHEPD 1709 +D + K E E D Sbjct: 833 REDAPVRWYKDGQEVEESD 851 Score = 56.0 bits (129), Expect = 1e-05 Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 5/112 (4%) Query: 496 PVFEKPTSEEQSMAPIFVEKLR--PKH--TPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 P P +++ AP+ VE L+ PK +G +F C V G P P+I W + + Sbjct: 229 PPESPPADPDEAPAPV-VEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLL 287 Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 P + MY D D L + +D G + C A+N+AG S +L V+ P Sbjct: 288 PDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339 Score = 50.0 bits (114), Expect = 7e-04 Identities = 88/418 (21%), Positives = 155/418 (37%), Gaps = 34/418 (8%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C L P ++ W GEE+V + + E + L + V+ G Y + Sbjct: 916 VVLTCELCR-PWAEVRWTKDGEEVVESPALLLQKEDTVRR----LVLPAVQLEDSGEY-L 969 Query: 711 VAVNREGEASLPIVLKIKTGEKEPP-QVIEPLK--SMIVRQGESVILSAQVVGNPRPTIT 767 ++ E AS + + EPP ++I P ++I E V+L ++ P + Sbjct: 970 CEIDDES-ASFTVTVT------EPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAP-VR 1021 Query: 768 WCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W K+ V+ AL + DG + +L + +D G + A + SA TV Sbjct: 1022 WYKDGLEVEESEALVLERDGPRCRL-VLPAAQPEDGGEFVCDA------GDDSAFFTVTV 1074 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 TE + + V + L ++R P + W N + E + + + Sbjct: 1075 -TEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNGRPVQEGEGLELHAE 1132 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV--KHLQKSYETEE 942 G L I +G Y C + + G S V + V V + Q + Sbjct: 1133 GPRRVLCI-QAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTP 1191 Query: 943 GKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 G + L S +WY + + ++ ++ Q G D G C Sbjct: 1192 GGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDA 1251 Query: 1002 KDQETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKP 1058 ++ V+E + + + L V E D A E++ ADV W R+G ++ P Sbjct: 1252 PQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTP 1309 Score = 42.7 bits (96), Expect = 0.11 Identities = 44/237 (18%), Positives = 87/237 (36%), Gaps = 9/237 (3%) Query: 1461 ISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 + DA + + ++ V + E +Q +E + P E + L+C P V W +G Sbjct: 1060 VCDAGDDSAFFTVTVTEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHNG 1118 Query: 1520 KKLKTAKATYEN----RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 + ++ + + R Y C + G S V + + PV + Sbjct: 1119 RPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVV 1178 Query: 1576 SNE--DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 + E + + G + + + G P V WYK+G +L + + V+R++ Sbjct: 1179 APEAAQTRVRSTPGGDLELVVHLSG-PGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQ 1237 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690 + + +Y +A + V V + K P+ + E + E PP Sbjct: 1238 GARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSDLTPLTVHEGDDATFRCEVSPP 1294 >UniRef50_UPI00015B4DC5 Cluster: PREDICTED: similar to ENSANGP00000021721; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000021721 - Nasonia vitripennis Length = 1247 Score = 158 bits (384), Expect = 1e-36 Identities = 136/530 (25%), Positives = 238/530 (44%), Gaps = 52/530 (9%) Query: 539 PQITWFRQTAIIKPSQDFQMYY-DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 P+ W R P + F++ + D ++ LV + V PEDAG +TCVA+ + G S + E Sbjct: 666 PKFVWTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNISCSAE 725 Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L V+ ++ + E P + + V G +L+ ++ Sbjct: 726 LTVQGTVNQL--------------------LKEPAKPALQSESRTSEVSAGGSAMLDLQV 765 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P+P+I W G+EIV I E + + L I +V G Y + A N G Sbjct: 766 KGFPKPNITWTKDGKEIVAGGRIKYLWEDEESLS---LVIKSVTAADAGVYKIRARNELG 822 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775 E + I L +K+ P++ + ++S V+ E++ +S Q+ G+P P ++W K+NK + Sbjct: 823 EDNTQIELIVKSA----PKITKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILE 878 Query: 776 --KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV--ITVEEPTEENAE 831 + +K DT+++TI K ++D G Y++ A+N I ETS TV+ P Sbjct: 879 SDRTRISKEADDTYTLTI-KSACLEDSGSYSIIAKNE--INETSQFWDCTVKYP------ 929 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P + + ++E ++ L V + PS+TW ++ E+I S+ IT + +G L Sbjct: 930 PKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWIKDEEVIKISDRITISDEGNRHSLQ 989 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV--ILE 949 I + + D+ YK +N G S + + + F K LQ TE V + + Sbjct: 990 IDKL-LDTDTATYKVQVANKDGARSEQTAIQVRSAPL-FKKKLQDKTATENEANVELLAQ 1047 Query: 950 CQTSHTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QE 1005 ++ WY K+IS + +EG G C K+ + Sbjct: 1048 VESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGES 1107 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGE 1054 +S+ + P+ I+KL D +VKE + L V++++ A +V W +DG+ Sbjct: 1108 SSSASLTVNFRPKLIKKLADQKVKEGETLKLTVQVSAVPAPEVQWFKDGQ 1157 Score = 157 bits (382), Expect = 2e-36 Identities = 186/797 (23%), Positives = 337/797 (42%), Gaps = 75/797 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPD-IAWLFKGEEIVPDENISVAIESDMHMYC 692 P F + V+ G EC L + + WL + + D+ ++ + S + Sbjct: 443 PQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPM--DDKLADRVRSSVEGST 500 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGE 750 L+I NV + G Y A N EG A+ L ++ T E++ + +VR + Sbjct: 501 YKLQIENVLESDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANSPIFLVRLKD 560 Query: 751 SVILS-------AQVVGNPRPTITWCKNNKP-------VKALPTKSDGDTHSITILKPKK 796 + +L ++ G+P P + + K+ P V+ + K+D + I I +K Sbjct: 561 TELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFYEIVIPDVQK 620 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 +D G Y+ A+N G A A ++V + A P +G ++ A Sbjct: 621 -QDAGKYSCTAQNRFGEASCEASVSVTDEKLMFAGLP-------------EGLLEPGAE- 665 Query: 857 TRNPVPSITWYRNNEIISPSETITQNF-DGEN-IELVITNVDSEIDSGDYKCVASNSAGK 914 P W R+ P E F D E+ + LV +V E D+G Y CVA S G Sbjct: 666 -----PKFVWTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPE-DAGLYTCVAQTSTGN 719 Query: 915 SSHGARVTIDVEKVTFVKH-----LQKSYETEE---GKTVILECQTSH--TVSTKWYHNK 964 S A +T+ +K LQ T E G + +L+ Q + W + Sbjct: 720 ISCSAELTVQGTVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDG 779 Query: 965 KEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTML-VVKETIPEFI 1020 KEI +G + + ++ D GV K +++ E +T + ++ ++ P+ Sbjct: 780 KEIVAGGRIKYLWEDEESLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKIT 839 Query: 1021 RKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 ++++ F V+ ++ + V+I S +V W +D + I ++ L I++ Sbjct: 840 KRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSA 899 Query: 1080 SVHDEGEYSCILRDE-SCTAEV--TVVELPPEIITRLQNQK-VNKGNKATFEIELTKG-D 1134 + D G YS I ++E + T++ V+ PP+I L + + +G+ T +E+ Sbjct: 900 CLEDSGSYSIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYP 959 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD-DAGEYSCEVGN-----SKCTAI 1188 V W KD I+ S+ I ++ +G + L+I D LD D Y +V N S+ TAI Sbjct: 960 PSVTWIKDEEVIKISDRITISDEGNRHSLQI-DKLLDTDTATYKVQVANKDGARSEQTAI 1018 Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY-KKKSVIEDTEKFTLISD 1247 P L+ AN + VE + +V+WY K + E+ +++++ + Sbjct: 1019 QVRSAPLFKKKLQDKTATENEANVELLAQVESFSKP-EVSWYFAGKKISEEKKEYSMSEE 1077 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVT 1306 L I+ + +YTC + + + V F PK++ + ++K G + Sbjct: 1078 GNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIKKLADQKVKEGETLK 1137 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS---KSASLTIKKVENTDAGIYKLRLE 1363 L V A P P +W + + + K S DS ++ LT+ ++ TD G+Y++R + Sbjct: 1138 LTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKGTDGGVYEVRAK 1197 Query: 1364 NNCGHADVEMNVTILDK 1380 N+ G + V +L K Sbjct: 1198 NDLGFVSSKSKVIVLTK 1214 Score = 143 bits (347), Expect = 4e-32 Identities = 151/693 (21%), Positives = 291/693 (41%), Gaps = 42/693 (6%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT-ITWCKNNKPVK-----AL 778 L + T + PQ P++ V GE + + + + W K+NKP+ + Sbjct: 433 LALSTNDAGRPQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPMDDKLADRV 492 Query: 779 PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE------NAEP 832 + +G T+ + I + D G+Y A N EG A +A + V+E T E +A Sbjct: 493 RSSVEGSTYKLQIENVLE-SDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANS 551 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS----ETITQNFDGENI 888 P+F+ R ++ + E ++ + ++ +P P + ++++ I + + + D Sbjct: 552 PIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFY 611 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET-EEGKTVI 947 E+VI +V + D+G Y C A N G++S A V++ EK+ F + E E K V Sbjct: 612 EIVIPDVQKQ-DAGKYSCTAQNRFGEASCEASVSVTDEKLMFAGLPEGLLEPGAEPKFVW 670 Query: 948 LECQTSHTVSTKW---YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 ++ + + ++ + + + E ++ + Q Sbjct: 671 TRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNIS-CSAELTVQ 729 Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNK 1062 T L+ + P + + EV A+L++++ ++ W +DG EI+ + K Sbjct: 730 GTVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIK 789 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVN 1119 Y +E + L I++ + D G Y R+ E T +V+ P+I R+++ V Sbjct: 790 YLWEDEESL-SLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKITKRMESFSVQ 848 Query: 1120 KGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG-KKQKLKIYDCDLDDAGEY 1176 +++ +G + V W+KD I S+ +++ + L I L+D+G Y Sbjct: 849 SEETINMSVQI-QGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSACLEDSGSY 907 Query: 1177 SC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 S E+ + TV+ P I L P I + Y+ VE D VTW K Sbjct: 908 SIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIEEGDSLTLYVEVE-SDYPPSVTWIK 966 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL--DAKSTTKLKVEVVEFPPK 1289 + VI+ +++ T+ + + +L I K + D Y + D + + ++V P Sbjct: 967 DEEVIKISDRITISDEGNRHSLQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSAPLF 1026 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIK 1348 + + + ++V LL ++F +P W KI ++ K S + LTIK Sbjct: 1027 KKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIK 1086 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + AG Y + +N G + ++T+ +P Sbjct: 1087 SAKTECAGKYTCKAKNEVGESSSSASLTVNFRP 1119 Score = 127 bits (306), Expect = 4e-27 Identities = 158/692 (22%), Positives = 273/692 (39%), Gaps = 57/692 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETAD-VVWERDGEIIKPK-KNKYDFEKRGHIRK 1073 P+F ++ +V+ + A E + +SE+A +VW +D + + K ++ G K Sbjct: 443 PQFETPIEGCQVEPGECATFECTLKSSESASKMVWLKDNKPMDDKLADRVRSSVEGSTYK 502 Query: 1074 LYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPE------------IITRLQNQK 1117 L I N D G Y + +CTA++ V E E + RL++ + Sbjct: 503 LQIENVLESDSGIYIAHAANGEGSATCTAQLVVQEFTAEEKKARADANSPIFLVRLKDTE 562 Query: 1118 VNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQK----LKIYDCDLD 1171 + + F I++ KGD +++FKDG I N + K K + I D Sbjct: 563 LLENTYLRFMIKI-KGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFYEIVIPDVQKQ 621 Query: 1172 DAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-----PD 1222 DAG+YSC G + C A ++V + + F LPE +L P ++ P+ Sbjct: 622 DAGKYSCTAQNRFGEASCEASVSVTDEKLMFA-GLPEGLLEPGAEPKFVWTRDGVPFDPE 680 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 E V + + + + D T + + T + C + L + +L E Sbjct: 681 ERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGNISC--SAELTVQGTVNQLLKE 738 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-DSK 1341 + P + R + G L + + FP+PN W + K I K D + Sbjct: 739 PAK--PALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIKYLWEDEE 796 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 S SL IK V DAG+YK+R N G + ++ + + P + + S Sbjct: 797 SLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKITKRMESFSVQSEETINMS 856 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVD 1460 + + + + +Y + +++ K T T +I++ S + A NE++ Sbjct: 857 VQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKSACLEDSGSYSIIAKNEIN 916 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 ET++++ T P + K L + E + + L P VTW +D Sbjct: 917 -----ETSQFWDC---TVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWIKDE 968 Query: 1520 KKLKTA-KATYE---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 + +K + + T NR YK N G + ++ P+ Sbjct: 969 EVIKISDRITISDEGNRHSLQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSAPLFKK 1028 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKE 1634 +D + L+ A +E PEV WY G K+ E KEY+++ + + IK Sbjct: 1029 KLQDKTATENEANVELL-AQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTIKS 1087 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K + KYT +A N G SS +L V +P Sbjct: 1088 AKTECAGKYTCKAKNEVGESSSSASLTVNFRP 1119 Score = 117 bits (282), Expect = 3e-24 Identities = 156/717 (21%), Positives = 280/717 (39%), Gaps = 77/717 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+ +L+D E+ E ++I + A D+ + +DG I K + + + Y Sbjct: 552 PIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQIVREKADKGFY 611 Query: 1076 ---IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 I + D G+YSC ++ SC A V+V + + L + G + F Sbjct: 612 EIVIPDVQKQDAGKYSCTAQNRFGEASCEASVSVTD-EKLMFAGLPEGLLEPGAEPKFV- 669 Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL--DDAGEYSC----EVGN 1182 W +DG ++ + L + + +DAG Y+C GN Sbjct: 670 ----------WTRDGVPFDPEERFKVLFKDSEDTLALVFQHVKPEDAGLYTCVAQTSTGN 719 Query: 1183 SKCTAILTVEEPSINFTLRLP---------EFILVPANTDAYLTVEIPD-ETLDVTWYKK 1232 C+A LTV+ ++N L+ P V A A L +++ ++TW K Sbjct: 720 ISCSAELTVQG-TVNQLLKEPAKPALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKD 778 Query: 1233 -KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKI 1290 K ++ L D + +L+I+ T D Y + ++E +V+ PKI Sbjct: 779 GKEIVAGGRIKYLWEDEESLSLVIKSVTAADAGVYKIRARNELGEDNTQIELIVKSAPKI 838 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKK 1349 + ++ + + V Q P P W ++K I + T+ S ++ +LTIK Sbjct: 839 TKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADDTYTLTIKS 898 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP---GKPNILEIDSSSINICWDEPEN 1406 D+G Y + +N + T+ P G+P ++E Sbjct: 899 ACLEDSGSYSIIAKNEINETSQFWDCTVKYPPKITKGLGEPRLIE--------------- 943 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD--A 1464 G+S +Y VE + WI + + K I + + + + + D + Sbjct: 944 EGDSLTLYVEVESDYPPSVTWIKDEEVIKISDRITISDEGNRHSLQIDKLLDTDTATYKV 1003 Query: 1465 SETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNE-DIELTCIFGGVPQPKVTWYRDGK 1520 + ++T IQ +P +K L++ T NE ++EL +P+V+WY GK Sbjct: 1004 QVANKDGARSEQTAIQVRSAPLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGK 1063 Query: 1521 KLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 K+ K Y N Y C A N+ GE +S + + +P + Sbjct: 1064 KISEEKKEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIK 1123 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI---TTKEKTSVIRI 1632 D QK K G+ +T + +P PEV W+K+G ++ D I + + + + + Sbjct: 1124 KLAD--QKVKEGETLKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTV 1181 Query: 1633 KELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 LK + Y + A N G + S + L ++ S+ V ++S + T E Sbjct: 1182 TLLKGTDGGVYEVRAKNDLGFVSSKSKVIVLTKSEEQSEEATKVAEEDVSAQKQTAE 1238 Score = 93.9 bits (223), Expect = 4e-17 Identities = 98/425 (23%), Positives = 180/425 (42%), Gaps = 58/425 (13%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP +++ T+ Q++G P P+++W++ I S ++ + D+ Sbjct: 835 APKITKRMESFSVQSEETINMSVQIQGSPVPEVSWYKDNKRILESDRTRISKEADD---- 890 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 T+T K+A L D GS ++ D Sbjct: 891 -----------TYTLTIKSAC--------------LEDSGS-YSIIAKNEINETSQFWDC 924 Query: 629 LEGIPPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIES 686 PP +K + + ++EG + L + + P + W+ K EE++ + I+++ E Sbjct: 925 TVKYPPKITKGLGEPRLIEEGDSLTLYVEVESDYPPSVTWI-KDEEVIKISDRITISDEG 983 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + H L+I + TY V N++G S +++++ P + L+ Sbjct: 984 NRHS----LQIDKLLDTDTATYKVQVANKDGARSEQTAIQVRSA----PLFKKKLQDKTA 1035 Query: 747 RQGES-VILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEG 801 + E+ V L AQV +P ++W K + K +G+ + +TI K K + G Sbjct: 1036 TENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGNCYKLTI-KSAKTECAG 1094 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 YT KA+N G + +SA +TV N P L I + + VKE T+KL +V+ P Sbjct: 1095 KYTCKAKNEVGESSSSASLTV------NFRPKL-IKKLADQKVKEGETLKLTVQVSAVPA 1147 Query: 862 PSITWYRNNEIISPSETITQNFDG---ENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P + W+++ + ++ I + D EN +L +T + D G Y+ A N G S Sbjct: 1148 PEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKG-TDGGVYEVRAKNDLGFVSSK 1206 Query: 919 ARVTI 923 ++V + Sbjct: 1207 SKVIV 1211 Score = 70.5 bits (165), Expect = 5e-10 Identities = 55/206 (26%), Positives = 101/206 (49%), Gaps = 17/206 (8%) Query: 634 PTFSKKPKAQYVDEG-SDILLECRLVAIPEPDIAWLFKGEEIVPDEN-ISVAIESDMHMY 691 P F KK + + E +++ L ++ + +P+++W F G++I ++ S++ E + Sbjct: 1024 PLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMSEEGN---- 1079 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 C L I + K G YT A N GE+S L + P++I+ L V++GE+ Sbjct: 1080 CYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFR----PKLIKKLADQKVKEGET 1135 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG---DTHSITILKPKKVKDEGVYTL 805 + L+ QV P P + W K+ + V A + D + + +T+ K D GVY + Sbjct: 1136 LKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQRLENYDLTVTLLKGT-DGGVYEV 1194 Query: 806 KAENSEGIAETSAVITVEEPTEENAE 831 +A+N G + + + V +EE +E Sbjct: 1195 RAKNDLGFVSSKSKVIVLTKSEEQSE 1220 Score = 56.4 bits (130), Expect = 8e-06 Identities = 33/101 (32%), Positives = 56/101 (55%), Gaps = 3/101 (2%) Query: 502 TSEEQSMAPIFVEKLRPKH-TPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMY 559 T+ + AP+F +KL+ K T + + V+ QVE + +P+++W F I + +++ M Sbjct: 1016 TAIQVRSAPLFKKKLQDKTATENEANVELLAQVESFSKPEVSWYFAGKKISEEKKEYSMS 1075 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ++ N L I+ E AG +TC AKN G +SS+ L V Sbjct: 1076 -EEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASLTV 1115 Score = 54.4 bits (125), Expect = 3e-05 Identities = 27/93 (29%), Positives = 46/93 (49%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P + R G + + QV+G+P+P ITW + I + ++D+ +LV Sbjct: 742 PALQSESRTSEVSAGGSAMLDLQVKGFPKPNITWTKDGKEIVAGGRIKYLWEDEESLSLV 801 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 I+ V DAG + A+N G ++ ELIV++ Sbjct: 802 IKSVTAADAGVYKIRARNELGEDNTQIELIVKS 834 Score = 51.6 bits (118), Expect = 2e-04 Identities = 48/174 (27%), Positives = 73/174 (41%), Gaps = 24/174 (13%) Query: 455 WWYVQKHLTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMA--- 509 W++ K ++EEK +Y M E N Y ++ E K K E S + Sbjct: 1058 WYFAGKKISEEK----KEYSMSEEGNCYKLTIKSAKTECAGKYTCKAKNEVGESSSSASL 1113 Query: 510 -----PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ------TAIIKPSQDFQM 558 P ++KL + +G T++ QV P P++ WF+ A IK S+D Q Sbjct: 1114 TVNFRPKLIKKLADQKVKEGETLKLTVQVSAVPAPEVQWFKDGQEVNADARIKISRDSQR 1173 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612 + D TL + D G + AKN GF SS +++IV + E T Sbjct: 1174 LENYDLTVTL----LKGTDGGVYEVRAKNDLGFVSSKSKVIVLTKSEEQSEEAT 1223 Score = 45.2 bits (102), Expect = 0.020 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 1/137 (0%) Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 +L +++ ++ + T A + P KK Q V EG + L + Sbjct: 1082 KLTIKSAKTECAGKYTCKAKNEVGESSSSASLTVNFRPKLIKKLADQKVKEGETLKLTVQ 1141 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 + A+P P++ W G+E+ D I ++ +S + L +T +K G Y V A N Sbjct: 1142 VSAVPAPEVQWFKDGQEVNADARIKISRDS-QRLENYDLTVTLLKGTDGGVYEVRAKNDL 1200 Query: 717 GEASLPIVLKIKTGEKE 733 G S + + T +E Sbjct: 1201 GFVSSKSKVIVLTKSEE 1217 Score = 44.4 bits (100), Expect = 0.035 Identities = 26/105 (24%), Positives = 54/105 (51%), Gaps = 3/105 (2%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQ 557 E+ + + +PIF+ +L+ + + ++F +++G P P + +F+ I ++ Q Sbjct: 541 EEKKARADANSPIFLVRLKDTELLENTYLRFMIKIKGDPAPDLKFFKDGVPIDSKNERVQ 600 Query: 558 MYYD--DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + D +VI +V +DAG ++C A+N G AS + V Sbjct: 601 IVREKADKGFYEIVIPDVQKQDAGKYSCTAQNRFGEASCEASVSV 645 >UniRef50_Q86VF2 Cluster: EEF1A2 binding protein; n=9; Euteleostomi|Rep: EEF1A2 binding protein - Homo sapiens (Human) Length = 868 Score = 157 bits (382), Expect = 2e-36 Identities = 106/473 (22%), Positives = 196/473 (41%), Gaps = 11/473 (2%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547 L ++ +P E L+C P TW++DG KL T + Sbjct: 79 LADMEVQPGEAATLSCTLTSDLGPG-TWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGT 137 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITIS-NEDIKQKH--KVGDEWLVTAVIEGIPPPEV 1604 G+ ++ + +Q P I E +++ K G +V + P + Sbjct: 138 QAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQA 197 Query: 1605 IWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 W K+G ++ +D+E + + + + + R +Y++ + G+ E+TL+V Sbjct: 198 AWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQV 257 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 DKP P+GP+ +++ R V + W+PP D+GG + Y +E+ + + W+KV + D Sbjct: 258 IDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPAD 317 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 T+ + +Y FRV A G EALESE I++ A + ++ Sbjct: 318 STTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILV--APEALPKAPSAPAILSASSQ 375 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRI 1839 + +TW G + I+ Y +E +++G W R + + Y+FR+ Sbjct: 376 GITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRV 435 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A G P D + + PP RN V++ ++ S+TL W P++ G Sbjct: 436 TAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQG 495 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 Y++E + W V + + ++ + R++A N G S P+ Sbjct: 496 YVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPS 548 Score = 98.7 bits (235), Expect = 2e-18 Identities = 150/686 (21%), Positives = 264/686 (38%), Gaps = 41/686 (5%) Query: 1113 LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDD 1172 L + +V G AT LT WFKDG ++ + + DG L I Sbjct: 79 LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQ 138 Query: 1173 AGEYSCEVGNSKCTAILTVEE-PSI--NFTLRLPEFILVPANTDAYLTVEIPDET-LDVT 1228 AG Y+ G+ + A LTV++ P+I + T +L E ++V A + + + Sbjct: 139 AGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAA 198 Query: 1229 WYKKKSVI---EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEV 1283 W K + + D E + D R L + D +Y+ L + + L ++V Sbjct: 199 WRKDGAEVVGSSDREAQVDLGDGYTR-LCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQV 257 Query: 1284 VEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS-IDSK 1341 ++ P P E + + G + + + ++V + + K + Sbjct: 258 IDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPAD 317 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP----PGKPNILEIDSSSI 1397 S + T VE +++R + G + + IL P P P IL S I Sbjct: 318 STTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQGI 377 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 + W P G++ I+ Y++E ++ + W +V + + + + ++ +++ Y FR A Sbjct: 378 TLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTA 437 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF-----GGVPQ 1510 V + ++ V ++ P + + L+ +T N I L+ G Q Sbjct: 438 VAPSGPGEPGPPSD--AVFARDPMRPPGLVRNLQ-VTDRSNTSITLSWAGPDTQEGDEAQ 494 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCIAFNDHGEVETSCVVGIQ 1568 V L+ Y + A N+ G+ + S + + Sbjct: 495 GYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLV 554 Query: 1569 QKPVITISNE---DIKQKH----KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 Q +T+ + D K KVGD V E +P PEV W K+G L K Sbjct: 555 QAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDG--LPLPKRSVT 612 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISR 1680 TK+ + + I S S YT+ G + ++V P P GP+ ++E Sbjct: 613 VTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQAP-GPIHLQENVP 671 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 +VT EW+P D+ YA+ + W + AD + + + EY FR Sbjct: 672 GTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAAD-RIYTNRFTLLGILPGHEYHFR 730 Query: 1741 VIAQNPVGFSEALE-SEPIVIKTALD 1765 V+A+N +G S+ + S+P I D Sbjct: 731 VVAKNELGASKPSDTSQPWCIPRQRD 756 Score = 90.6 bits (215), Expect = 4e-16 Identities = 101/474 (21%), Positives = 169/474 (35%), Gaps = 36/474 (7%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+K+G KL + I ++ + + +YT AG E TL V D Sbjct: 105 WFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTF----VAGDQQSEATLTVQDS 160 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK-----VADVD 1720 P+ P + ++ RE + ++ P+ + K + H P W K V D Sbjct: 161 PTI--APDVTEKL-REPLVVKAGKPV------IVKIPFQSHLPIQAAWRKDGAEVVGSSD 211 Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKTAL-----DVPSXXXXXX 1774 R+ + C + G +S L SE ++ L D P Sbjct: 212 REAQVDLGDGYTRLC---LPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPM 268 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT 1833 V + W P NGG + Y VE +Q G+ W + Sbjct: 269 EVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEP 328 Query: 1834 --TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 Y FR+ A G S++ + + L P P + ++S+ +TL WT P Sbjct: 329 GRKYTFRVRAVTSEGAGEALESEEILVAPEAL--PKAPSAPAILSASSQGITLTWTAPRG 386 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 G + I Y+IE + +WT + + ++++ + FR++A G P Sbjct: 387 PGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEP 446 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + P L++ + + SW P+ G GY + + Sbjct: 447 GPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSL 506 Query: 2012 MWM--EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 W+ VG V V T + + L Y +R+ A NE G S+P D + +P Sbjct: 507 QWLPCHVGTVPVTT--YTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMP 558 Score = 78.2 bits (184), Expect = 2e-12 Identities = 97/435 (22%), Positives = 166/435 (38%), Gaps = 27/435 (6%) Query: 1637 RSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 R ++ + S AG + S E+ + P P P I+ S + +T+ W P G Sbjct: 330 RKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAIL-SASSQGITLTWTAPRGPG 388 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 + Y IE+ + +N W V D + + + + C+Y FRV A P G E Sbjct: 389 SAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGP 448 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKW 1813 V P N S+ ++W + G Y VE+ + +W Sbjct: 449 PSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQW 508 Query: 1814 K--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + L Y R+ A NE G S P D T+ + + P+ Sbjct: 509 LPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALD---TLVQAMPVTVCPK- 564 Query: 1872 FVVSESTSRSVTLKWTE----PESNGGSPI--TNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 F+V ST +T+K + P S P+ ++ + + +S T VT G + + Sbjct: 565 FLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVT--VTKDG-LTQL 621 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 I D ++ + G + + S R+ + A P P P+ ++ V Sbjct: 622 LIPVAGLSDSGLYTVVLRTLQGKEV---AHSFRI-RVAACPQAP-GPIHLQENVPGTVTA 676 Query: 1986 SWG-TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 W +P+ PL Y + R W E + T +F + + H Y R+ A+ Sbjct: 677 EWEPSPDEAQDVPL-HYAVFTRSSAHGPWHEAAD-RIYTNRFTLLGILPGHEYHFRVVAK 734 Query: 2045 NEIGLSEPLESDEPF 2059 NE+G S+P ++ +P+ Sbjct: 735 NELGASKPSDTSQPW 749 Score = 70.5 bits (165), Expect = 5e-10 Identities = 67/326 (20%), Positives = 120/326 (36%), Gaps = 8/326 (2%) Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 H+ GK +L IY D + + + P +F+ L + + P Sbjct: 28 HLGSRRSGKDGRLDIYGERRDATRSSTSRYKPGTGSFSKDAQGPMGHFSQGLADMEVQPG 87 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 A L+ + + TW+K + + D +L I YT V Sbjct: 88 EA-ATLSCTLTSDLGPGTWFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVA 146 Query: 1271 LDAKSTTKLKVE-VVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 D +S L V+ P + + RE +K G V + + +Q+ W + + Sbjct: 147 GDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEV 206 Query: 1329 KKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-G 1385 + +D L + D G Y + L + G E+ + ++DKP PP G Sbjct: 207 VGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQG 266 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNL 1443 + + + + + W P + G T+ YVVE ++ + W+ V T+ ++ Sbjct: 267 PMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHV 326 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTE 1469 + Y FR AV +A E+ E Sbjct: 327 EPGRKYTFRVRAVTSEGAGEALESEE 352 Score = 62.9 bits (146), Expect = 9e-08 Identities = 39/111 (35%), Positives = 55/111 (49%), Gaps = 6/111 (5%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 K P + +P + S P F+ LR P G C V+G PRP +TWF+ ++ + Sbjct: 761 KAPCYREP---DLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGN 817 Query: 554 QDFQMYYDD-DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 +Y D V +L I V P+D+G + VA+N G A ST LIV P Sbjct: 818 P--AVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEP 866 Score = 56.4 bits (130), Expect = 8e-06 Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 2/96 (2%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 + P+ + L+S ++ QG +S V G+PRP +TW KN++ ++ P D + L Sbjct: 772 QKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSL 831 Query: 793 KPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPT 826 V KD G Y AEN+ G A ++A + V EP+ Sbjct: 832 TIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEPS 867 Score = 53.2 bits (122), Expect = 8e-05 Identities = 48/247 (19%), Positives = 98/247 (39%), Gaps = 18/247 (7%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K G V + V ++A P P W+ + + K T L I +D+G+Y Sbjct: 577 VKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVTVTK--DGLTQLLIPVAGLSDSGLY 634 Query: 1359 KLRLENNCG-HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + L G + + P PG ++ E ++ W+ + ++Y V Sbjct: 635 TVVLRTLQGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAV 694 Query: 1418 EYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + W + I + ++ + Y FR A NE+ S S+T++ + + ++ Sbjct: 695 FTRSSAHGPWHEAADRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQ 754 Query: 1477 T---KIQSPTVEKP-----------LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 +++P +P L++ + ++C G P+P VTW+++ + L Sbjct: 755 RDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSL 814 Query: 1523 KTAKATY 1529 + A Y Sbjct: 815 EGNPAVY 821 Score = 49.2 bits (112), Expect = 0.001 Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 10/167 (5%) Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 F + L D EV+ + A L + S+ W +DG + + F++ G + L+I + Sbjct: 75 FSQGLADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLTTQDGVI-FKQDGLVHSLFITH 133 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELP---PEIITRLQNQKVNKGNKATFEIELTKGDA 1135 G Y+ + D+ A +TV + P P++ +L+ V K K +++ Sbjct: 134 VQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVI-VKIPFQSH 192 Query: 1136 L---VRWFKDGSEIQFSN--HIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 L W KDG+E+ S+ Q+ + +L + D G+YS Sbjct: 193 LPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYS 239 Score = 39.5 bits (88), Expect = 0.99 Identities = 22/78 (28%), Positives = 33/78 (42%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ ++G P P V W+KN LE + T + I + S +Y Sbjct: 788 GCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAV 847 Query: 1647 ASNTAGTSSVEVTLKVYD 1664 A NT G + TL V + Sbjct: 848 AENTLGQAVSTATLIVIE 865 Score = 38.3 bits (85), Expect = 2.3 Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 7/128 (5%) Query: 800 EGVYT-LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE--ITVKEKGTIKLVARV 856 EG + + A N G ++ SA+ T+ + P ++ + +TVK T+++ Sbjct: 530 EGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSF 589 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS- 915 P+P +TW ++ + P ++T DG + ++ V DSG Y V GK Sbjct: 590 EAMPMPEVTWLKDG-LPLPKRSVTVTKDG--LTQLLIPVAGLSDSGLYTVVLRTLQGKEV 646 Query: 916 SHGARVTI 923 +H R+ + Sbjct: 647 AHSFRIRV 654 >UniRef50_Q7PF94 Cluster: ENSANGP00000024414; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000024414 - Anopheles gambiae str. PEST Length = 2305 Score = 157 bits (381), Expect = 3e-36 Identities = 145/602 (24%), Positives = 257/602 (42%), Gaps = 57/602 (9%) Query: 459 QKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAPIFVEKLR 517 QK + E + + + ++ + Q++++E KI + V S+ + P VEKL+ Sbjct: 1572 QKRVQEVTDKIAEESVREDRQLIETTQQQISETKIQEQTV---KISKPKVQPPNIVEKLQ 1628 Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 P+ V C++EG P P + W+ ++ S ++ M +D VATL I V P Sbjct: 1629 PQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVED-VATLEIATVQPYH 1687 Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 G +TC AKN AG A S ++V+ +HG P F Sbjct: 1688 VGIYTCEAKNVAGVAISKANIVVQEK-PEHGEA-----------------------PRFV 1723 Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 K + ++ + + C++ IP P + WL EI+ +E + + L + Sbjct: 1724 VPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTV 1783 Query: 698 TNVKKFQEGTYTVVAVNREGEAS-------LPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + K+ +TVVA N+ G+A +V++ PQ+++PL++ +VR G Sbjct: 1784 KHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGS 1843 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS-ITILKPKKVKDE--GVYTLKA 807 +++ + G P+PT+ W +N+K + + T + L+ ++V + G Y + Sbjct: 1844 TLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITV 1903 Query: 808 ENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G A++SA + + + T+ + A+ P FI + E L A V P + W Sbjct: 1904 TNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQW 1963 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV----T 922 ++ I S + EN ++I + D+G Y C A N AG + A V T Sbjct: 1964 FKEGAAIK-STNEQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDT 2022 Query: 923 IDVEKVT------FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHRE 974 I+ E+VT F++ + K +G+ + LECQ K WYHN + I ++ Sbjct: 2023 IETEEVTEYISPRFLETI-KPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQ 2081 Query: 975 IIQEGRXX-XXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQDFEVKEK 1031 + Q+ D G C+ ++ E V E++ + F E+ Sbjct: 2082 VQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEE 2141 Query: 1032 DV 1033 D+ Sbjct: 2142 DL 2143 Score = 118 bits (284), Expect = 2e-24 Identities = 121/510 (23%), Positives = 205/510 (40%), Gaps = 45/510 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP +K + Q + +LL CR+ +P P + W F + + + D+ Sbjct: 1620 PPNIVEKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDV---- 1675 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + L+I V+ + G YT A N G A IV++ K E P+ + PLK + Q Sbjct: 1676 ATLEIATVQPYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLKIELNEQKT 1735 Query: 751 SVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDT-HSITILKPKKVKDEGVYT 804 ++ QV G P P + W ++ + + + T + T H +K K V+T Sbjct: 1736 IATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFT 1795 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEP----PLFINRFQEITVKEKGTIKLVARVTRNP 860 + AEN G A A + ++ E A+P P + + V+ T+ R T P Sbjct: 1796 VVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQP 1855 Query: 861 VPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P++ W+RN+ EI+ E + + L I V + G Y+ +N AG++ A Sbjct: 1856 KPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQ-RGGKYEITVTNEAGQAKSSA 1914 Query: 920 RVTI----DVEKVTFVKHLQKSYE--TEEGKTVILECQT-SHTVST-KWYHNKKEISGMD 971 V I D ++ + ++ E + ILE S+ ST +W+ I + Sbjct: 1915 SVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTN 1974 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKC---IVKDQETSTMLV----------VKETI-P 1017 + I+ + D G C V TST V V E I P Sbjct: 1975 EQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISP 2034 Query: 1018 EFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 F+ ++ V + + LE ++ + V W + ++I+ K+K + L I Sbjct: 2035 RFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSI 2094 Query: 1077 RNTSVHDEGEYSCI----LRDESCTAEVTV 1102 D+GEY+C+ + + C A V V Sbjct: 2095 SEVFPEDKGEYTCVATNKIGEAICRATVNV 2124 Score = 106 bits (255), Expect = 6e-21 Identities = 131/561 (23%), Positives = 226/561 (40%), Gaps = 90/561 (16%) Query: 350 DIVESKKDENEIIQEKQT-----LEELPKEDVPEQYTITPRKSSAQKIDE--IVDEVTIK 402 +I+E +++E E E++T + PK++VP +T+ + + + + + + Sbjct: 1759 EIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVM 1818 Query: 403 KRLNPFEI---FYTPVE---VRCGDTVFAVYSYVAETDEAIN-------LVEGERLYILD 449 +R P + P+E VR G T+ + + + +VE E I+ Sbjct: 1819 ERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIIT 1878 Query: 450 TSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMA 509 T + +T ++G +Y + N Q K + + T +++ A Sbjct: 1879 TEEYYSRLEIRRVTRQRG---GKYEITVTNEAG--QAKSSASV----AISDATDTDEAKA 1929 Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E L PK + E VE YP WF++ A IK + + Q +N + L+ Sbjct: 1930 PRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNE-QRIVTKENRSILI 1988 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I D G +TC A+N AG +ST + ++ Sbjct: 1989 IESFTRRDTGAYTCRAENVAGSVTSTATV-------------------QTLDTIETEEVT 2029 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E I P F + K V +G + LEC++VA+P P + W + I E ++ D Sbjct: 2030 EYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLI--QETKDKQVQQDST 2087 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--------------- 734 C VL I+ V +G YT VA N+ GEA + ++ E P Sbjct: 2088 GRC-VLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEEDLLTD 2146 Query: 735 ------PQVIEPLK--SMIVRQGESVI---------LSAQVVGNPRPTITWCKNNK---P 774 + EP++ IV+Q ++I L +V+ +P+P I W K + P Sbjct: 2147 KSISTLEEYAEPIEYAPQIVKQLPTIIHSQERELTKLEVKVLAHPKPQIRWLKAGEEIIP 2206 Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA-EPP 833 ++ D SI I+ D G T +A N+ G+A T+ + VEE A P Sbjct: 2207 SDEFQIENFDDGTSILIINDIYPDDSGEITFEAHNALGVAMTTTELVVEEIVGTKAYRKP 2266 Query: 834 LFINRFQEI--TVKEKGTIKL 852 ++ +E+ ++E T +L Sbjct: 2267 EWVQHMEELKEALQESSTEEL 2287 Score = 99.5 bits (237), Expect = 9e-19 Identities = 136/561 (24%), Positives = 218/561 (38%), Gaps = 75/561 (13%) Query: 435 EAINLVEGERLYILDTSNQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDK 494 + I ++E E I + +V+ + K VP + + N K N I Sbjct: 1756 DEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQS 1815 Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 + V E+ ++ ++AP V+ L + GST+ FEC+ G P+P + WFR + I + Sbjct: 1816 V-VMER--AKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEE 1872 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614 + + ++ + L IR V + G + N AG A S+ + + SD Sbjct: 1873 EEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSASVAI----SD-------- 1920 Query: 615 XXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 D E P F + + + E +LE + + P W +G I Sbjct: 1921 ----------ATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAI 1970 Query: 675 VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKE 733 + + + S+L I + + G YT A N G S V + T E E Sbjct: 1971 KSTNEQRIVTKENR----SILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETE 2026 Query: 734 ------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDT 786 P+ +E +K V GE + L QVV P P + W N + ++ K D+ Sbjct: 2027 EVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDS 2086 Query: 787 HSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVE--------------------- 823 +L +V +D+G YT A N G A A + VE Sbjct: 2087 TGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQFRSSEEDLLTD 2146 Query: 824 ---EPTEENAEP----PLFINRFQEIT-VKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 EE AEP P + + I +E+ KL +V +P P I W + E I P Sbjct: 2147 KSISTLEEYAEPIEYAPQIVKQLPTIIHSQERELTKLEVKVLAHPKPQIRWLKAGEEIIP 2206 Query: 876 SETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 S+ +NFD L+I ++ + DSG+ A N+ G + + VE++ K Sbjct: 2207 SDEFQIENFDDGTSILIINDIYPD-DSGEITFEAHNALGVAM--TTTELVVEEIVGTKAY 2263 Query: 935 QKS---YETEEGKTVILECQT 952 +K EE K + E T Sbjct: 2264 RKPEWVQHMEELKEALQESST 2284 Score = 81.4 bits (192), Expect = 2e-13 Identities = 101/457 (22%), Positives = 174/457 (38%), Gaps = 31/457 (6%) Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 +K V E T+K S + R LI T Q T + +K KV+ PP IV Sbjct: 1572 QKRVQEVTDKIAEESVREDRQLIE---TTQQQISETKIQEQTVKISKPKVQ----PPNIV 1624 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + + + V L + P P +W N ++ ++ A+L I V+ Sbjct: 1625 EKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATLEIATVQ 1684 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI---LEID-SSSINICWDEPENT 1407 GIY +N G A + N+ + +KP P L+I+ + I + Sbjct: 1685 PYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLKIELNEQKTIATVTCQVA 1744 Query: 1408 GNSTI-IYYVVEYQEIDTTEWISVKNITKTQT-----SIQNLKTNSSYRFRAYAVNEVDI 1461 G T + ++ + EI E ++ + +T ++++ K N F A N+ Sbjct: 1745 GIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFTVVAENKFGK 1804 Query: 1462 SDASETTEYYKVIKETKIQS---PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + V+ E S P + +PL+ + C F G P+P V W+R+ Sbjct: 1805 AVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRN 1864 Query: 1519 GKKLKTAK-----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 K++ + T E Y+ N+ G+ ++S V I Sbjct: 1865 SKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSASVAISDATDT 1924 Query: 1574 TISN-----EDIKQKHKVGDE-WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 + E + K E ++ A +E P W+K G +++ E I TKE Sbjct: 1925 DEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNEQRIVTKENR 1984 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 S++ I+ R + YT A N AG+ + T++ D Sbjct: 1985 SILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLD 2021 Score = 81.0 bits (191), Expect = 3e-13 Identities = 150/710 (21%), Positives = 287/710 (40%), Gaps = 80/710 (11%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 +EP QV E + ++ + +I PR T K+ K + K + T + Sbjct: 1431 EEPAQVAETIVDIVAEEVLDLIPDLA----PRETAKKRKSRNK-KHVVFKEELSTFA--- 1482 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV--KEKGT 849 ++P++ +++ + E + I+ +S IT+ P + A P+ + +E T +++ Sbjct: 1483 MEPEEEEEQEEDEAEEEQVQEISRSS--ITLTRPDSKPAPVPVEELKMEEQTTEFRKEME 1540 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 +++ + + + + +++ + E ITQ + ++ V + E D + + + Sbjct: 1541 VRVQSNIVKKEKKRRVFIDDSQPLPELEIITQ----KRVQEVTDKIAEESVREDRQLIET 1596 Query: 910 NSAGKSSHGAR---VTIDVEKV---TFVKHLQKSYETEEGKTVILECQTSHTV--STKWY 961 S + V I KV V+ LQ E K V+L C+ + +WY Sbjct: 1597 TQQQISETKIQEQTVKISKPKVQPPNIVEKLQPQI-CEPDKPVLLRCRIEGVPFPTVQWY 1655 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKET-- 1015 N + + VG+ C K+ + +VV+E Sbjct: 1656 FNDTVLFASSEYIMNVVEDVATLEIATVQPYHVGIYTCEAKNVAGVAISKANIVVQEKPE 1715 Query: 1016 ---IPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDG-EIIKPKKNK---YDFEK 1067 P F+ L+ ++K +A + ++ T V W RD EII+ ++ + Y E+ Sbjct: 1716 HGEAPRFVVPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEER 1775 Query: 1068 RGHIRKLYIRNT--------SVHDEGEYSCILRDESCTAEVTVVE------LPPEIITRL 1113 GH+R L +++ +V E ++ + + + V+E + P+I+ L Sbjct: 1776 TGHVR-LTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPL 1834 Query: 1114 QNQKVNKGNKATFEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLD 1171 + Q V G+ FE T + V+WF++ EI + + +T + +L+I Sbjct: 1835 EAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQ 1894 Query: 1172 DAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFI--LVP---ANTDAYLTVEIPD 1222 G+Y E G +K +A + + + + + P FI LVP A + + + Sbjct: 1895 RGGKYEITVTNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVE 1954 Query: 1223 E--TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC----VLLDAKST 1276 T W+K+ + I+ T + +++ + LII T D YTC V ST Sbjct: 1955 SYPTSTFQWFKEGAAIKSTNEQRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTST 2014 Query: 1277 TKLKV-------EVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 ++ EV E+ P+ ++ + R+ G +TL A P P W N+++I Sbjct: 2015 ATVQTLDTIETEEVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLI 2074 Query: 1329 KKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 ++ K + DS L+I +V D G Y N G A V + Sbjct: 2075 QETKDKQVQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNV 2124 Score = 67.3 bits (157), Expect = 4e-09 Identities = 132/654 (20%), Positives = 243/654 (37%), Gaps = 71/654 (10%) Query: 718 EASLPIVLKIKTGEKEPPQVIEPLK----SMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 E S + + K P +E LK + R+ V + + +V + + +++ Sbjct: 1503 EISRSSITLTRPDSKPAPVPVEELKMEEQTTEFRKEMEVRVQSNIVKKEKKRRVFIDDSQ 1562 Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYT---LKAENSEGIAETSAVITVEEPTEENA 830 P+ L + +T K+ +E V L + I+ET + ++ Sbjct: 1563 PLPELEIITQKRVQEVT----DKIAEESVREDRQLIETTQQQISETKIQEQTVKISKPKV 1618 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 +PP + + Q + + L R+ P P++ WY N+ ++ S N + L Sbjct: 1619 QPPNIVEKLQPQICEPDKPVLLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATL 1678 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-----EKVTFVKHLQKSYETEEGKT 945 I V G Y C A N AG + A + + E FV L+ E E KT Sbjct: 1679 EIATV-QPYHVGIYTCEAKNVAGVAISKANIVVQEKPEHGEAPRFVVPLK--IELNEQKT 1735 Query: 946 V-ILECQTS--HTVSTKWYHNKKEISGMDHREI---IQEGRXXXXXXXXXXXXDVGVIKC 999 + + CQ + T +W ++ EI + EI +E +V V+ Sbjct: 1736 IATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTGHVRLTVKHPKQNVPVVFT 1795 Query: 1000 IVKDQETSTML---------VVKE------TIPEFIRKLQDFEVKEKDVAILEVEINSET 1044 +V + + + VV E P+ ++ L+ V+ + E + Sbjct: 1796 VVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQVVRTGSTLVFECRFTGQP 1855 Query: 1045 ADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAE 1099 V W R+ + I ++ + + +L IR + G+Y + +E+ +A Sbjct: 1856 KPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSAS 1915 Query: 1100 VTVVEL-------PPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNH 1151 V + + P I L + + + E + + + +WFK+G+ I+ +N Sbjct: 1916 VAISDATDTDEAKAPRFIEPLVPKLIAEAEVCILEASVESYPTSTFQWFKEGAAIKSTNE 1975 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFI--- 1206 ++ + L I D G Y+C N T+ TV+ T + E+I Sbjct: 1976 QRIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISPR 2035 Query: 1207 ----LVPANT--DAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTLISDVKKR-TLIIR 1256 + P LT+E + V WY +I++T+ + D R L I Sbjct: 2036 FLETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSIS 2095 Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 + +D+ EYTCV + + V P + V ++ R S+ LL D Sbjct: 2096 EVFPEDKGEYTCVATNKIGEAICRATVNVEPFEYVPDSEQF---RSSEEDLLTD 2146 Score = 56.0 bits (129), Expect = 1e-05 Identities = 51/209 (24%), Positives = 82/209 (39%), Gaps = 18/209 (8%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRXX 1534 ++P PLK E +TC G+P PKV W RD ++ + + YE R Sbjct: 1718 EAPRFVVPLKIELNEQKTIATVTCQVAGIPTPKVRWLRDEIEIIEEEEEEIETYYEERTG 1777 Query: 1535 XXXXXXXXXXXXX---YKCIAFNDHGEVETSCVVGIQQ------KPVITISN--EDIK-Q 1582 + +A N G+ V IQ KP + ++ Q Sbjct: 1778 HVRLTVKHPKQNVPVVFTVVAENKFGKAVGKANVYIQSVVMERAKPSAVAPQIVQPLEAQ 1837 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSS 1641 + G + G P P V W++N ++ E ++E ITT+E S + I+ + R Sbjct: 1838 VVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLEIRRVTRQRGG 1897 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 KY I +N AG + ++ + D E Sbjct: 1898 KYEITVTNEAGQAKSSASVAISDATDTDE 1926 Score = 54.0 bits (124), Expect = 4e-05 Identities = 28/82 (34%), Positives = 39/82 (47%) Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 L+ IEG+P P V WY N L EY + E + + I ++ H YT EA N Sbjct: 1639 LLRCRIEGVPFPTVQWYFNDTVLFASSEYIMNVVEDVATLEIATVQPYHVGIYTCEAKNV 1698 Query: 1651 AGTSSVEVTLKVYDKPSKPEGP 1672 AG + + + V +KP E P Sbjct: 1699 AGVAISKANIVVQEKPEHGEAP 1720 Score = 51.2 bits (117), Expect = 3e-04 Identities = 64/298 (21%), Positives = 112/298 (37%), Gaps = 17/298 (5%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLT 1346 P+IV ++ GS + + P+P +W NSK I+++ + + + + L Sbjct: 1828 PQIVQPLEAQVVRTGSTLVFECRFTGQPKPTVKWFRNSKEIVEEEEEVIITTEEYYSRLE 1887 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILE------IDSSSIN 1398 I++V G Y++ + N G A +V I D P +E I + + Sbjct: 1888 IRRVTRQRGGKYEITVTNEAGQAKSSASVAISDATDTDEAKAPRFIEPLVPKLIAEAEVC 1947 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNL--KTNSSYRFRAYAV 1456 I E+ ST ++ T E V ++ I++ + +Y RA V Sbjct: 1948 ILEASVESYPTSTFQWFKEGAAIKSTNEQRIVTKENRSILIIESFTRRDTGAYTCRAENV 2007 Query: 1457 NEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 S A+ +T + + + T+ SP + +K E + L C +P PKV W Sbjct: 2008 AGSVTSTATVQTLDTIETEEVTEYISPRFLETIKPTRVMDGERLTLECQVVAMPLPKVHW 2067 Query: 1516 YRDGK-----KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 Y + + K K + R Y C+A N GE V ++ Sbjct: 2068 YHNAQLIQETKDKQVQQDSTGRCVLSISEVFPEDKGEYTCVATNKIGEAICRATVNVE 2125 Score = 44.8 bits (101), Expect = 0.026 Identities = 62/268 (23%), Positives = 105/268 (39%), Gaps = 32/268 (11%) Query: 1416 VVEYQE---IDTTEWIS---VKNITKTQTSIQNLK-TNSSYRFRAYAVNEVDISDASETT 1468 +VE +E I T E+ S ++ +T+ + + TN + + ++ A V ISDA++T Sbjct: 1868 IVEEEEEVIITTEEYYSRLEIRRVTRQRGGKYEITVTNEAGQAKSSA--SVAISDATDTD 1925 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-- 1526 E K + P V K + E L P W+++G +K+ Sbjct: 1926 E----AKAPRFIEPLVPKLIAEA-----EVCILEASVESYPTSTFQWFKEGAAIKSTNEQ 1976 Query: 1527 --ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG----IQQKPVITISN--- 1577 T ENR Y C A N G V ++ V I+ + V + Sbjct: 1977 RIVTKENRSILIIESFTRRDTGAYTCRAENVAGSVTSTATVQTLDTIETEEVTEYISPRF 2036 Query: 1578 -EDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKE 1634 E IK + G+ + + +P P+V WY N ++ K+ + V+ I E Sbjct: 2037 LETIKPTRVMDGERLTLECQVVAMPLPKVHWYHNAQLIQETKDKQVQQDSTGRCVLSISE 2096 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + +YT A+N G + T+ V Sbjct: 2097 VFPEDKGEYTCVATNKIGEAICRATVNV 2124 Score = 41.5 bits (93), Expect = 0.25 Identities = 47/219 (21%), Positives = 95/219 (43%), Gaps = 17/219 (7%) Query: 167 KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNE-VPEKINVPDDKETSQTPTSFN 225 +P +P + ++ K PK +E+E K I + +PE + P+ + + P Sbjct: 556 RPLPEEPKEEVV--LKPIPKPTKENEPKETKEQTIKPKPMPELDDKPEPELELEKPAVPE 613 Query: 226 KRSKLTPIKIERKEME---VSTPQHAETVDGPQFXXXXXXXXXX--XXXXETSLVKLPKF 280 + + L P + +K +E + TP E V+ E SL +PK Sbjct: 614 EDTSLPPWRRGKKSVEKKPLPTPAEPEKVEQVTLKPTPRQKKELPKEAIEEVSLKPVPK- 672 Query: 281 QLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTE 340 K ++ + + PE ++ + K+ + + + ++K F P ++P+VEK E Sbjct: 673 --KPVVEEVATAEPEEVEEKTVKIVKKKK----PKAVTQQESLEKLEFTPTEVPEVEKME 726 Query: 341 LEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379 + + L + I ++ E + +Q + P+E+VPE+ Sbjct: 727 MPEKLEEVKPIEPEQEPEKPSWRRQQ--KPKPQEEVPEE 763 Score = 40.3 bits (90), Expect = 0.57 Identities = 48/228 (21%), Positives = 94/228 (41%), Gaps = 16/228 (7%) Query: 152 TLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINV 211 T K F +ED S + Q Q + ++K + + P + ++ E Sbjct: 336 TTPKPVEFTEREDSSTLKLEQTEQELSLDSKPTEQPVGWRRGPKERKPVVEPATEEP--A 393 Query: 212 PDDKETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXE 271 P+D+ +Q P R K P + K+ E + P+ E Sbjct: 394 PEDQPETQLPPWMRGR-KPGPKRELPKQPEPEKVEQVMLKPTPR----QKKELPKEAIEE 448 Query: 272 TSLVKLPKFQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPP 331 SL +PK K ++ + + PE ++ + K+ +++ + ++K F P Sbjct: 449 VSLKPVPK---KPVVEEVATAEPEEVEEKTVKIVKKKK----PKSVTQQESLEKLEFTPT 501 Query: 332 KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379 ++P+VEK E+ + L + I ++ E + +Q L+ P+E+VPE+ Sbjct: 502 EVPEVEKMEMPEKLEEVKPIEPEQEPEKPSWRRQQKLK--PQEEVPEE 547 Score = 37.5 bits (83), Expect = 4.0 Identities = 56/233 (24%), Positives = 94/233 (40%), Gaps = 26/233 (11%) Query: 185 PKLIEESEQPIAKTSEIDNEVP-EKINVPDDKETSQTPTSFNKRSKLTPIKIERKEMEVS 243 P++ E+ E + KT I EV E VP+ +TP K P++ E +E + Sbjct: 1146 PEIPEQEEVQLEKTEHIPEEVQKEPETVPEQPPWRRTP-------KPKPVETEEEEKKWP 1198 Query: 244 TPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRIKYITSWPPESIKPLISY 303 T + V+ P+ E P+ Q+ + K+ P E I + + Sbjct: 1199 TGKRRPPVEEPKEEVVLKPIPKPTKDVEPQ----PEQQITIKPKHPEPTPKEEIPEVTPW 1254 Query: 304 M-GSIKQNGILSRNIKEAAKVKKQVFVP-PK----LPDVEKTELEQPLFSYED--IVESK 355 G ++ + KE K K++ PK L + K E+P E+ IV K Sbjct: 1255 RRGKKEKPPVEEEEPKEWPKGKRRPLPETPKEEVVLKPIPKPSKEEPPKPAEEPTIVLPK 1314 Query: 356 KDENEIIQEKQT-----LEELPKEDVP-EQYTITPRKSSAQKIDEIVDEVTIK 402 E + KQ ++ELPKE+ P E+ T+ P + + +E+ +K Sbjct: 1315 PTVQEPEEPKQAPWRRGMKELPKEETPKEEITLKPIPKREEPEQTVQEEIILK 1367 Score = 37.1 bits (82), Expect = 5.3 Identities = 47/219 (21%), Positives = 92/219 (42%), Gaps = 17/219 (7%) Query: 167 KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNE-VPEKINVPDDKETSQTPTSFN 225 +P +P + I+ K PK +E+E K I + + E + P+ + + P Sbjct: 772 RPLPEEPKEEIV--LKPIPKPTKENEPKETKEQTIKPKPISELDDKPEPELELEKPAVPE 829 Query: 226 KRSKLTPIKIERKEME---VSTPQHAETVDGPQFXXXXXXXXXX--XXXXETSLVKLPKF 280 + + L P + +K +E + P E V+ E SL +PK Sbjct: 830 EDTSLPPWRRGKKPVEKKPLPPPAEPEKVEQVMLKPTPRQKKELPKEAIEEVSLKPVPK- 888 Query: 281 QLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTE 340 K ++ I PE ++ + K+ + + + ++K F P ++P+VEK E Sbjct: 889 --KPVVEEIAPTEPEEVEEKTVKIVKKKK----PKAVTQQESLEKLEFTPTEVPEVEKME 942 Query: 341 LEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQ 379 + + L + I ++ E + +Q + P+E+VPE+ Sbjct: 943 MPEKLEEVKPIEPEQEPEKPSWRRQQ--KPKPQEEVPEE 979 Score = 36.3 bits (80), Expect = 9.2 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 9/96 (9%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P P++ W K G ++ E+ I + TS++ I ++ S + T EA N G + Sbjct: 2191 PKPQIRWLKAGEEIIPSDEFQIENFDDGTSILIINDIYPDDSGEITFEAHNALGVAMTTT 2250 Query: 1659 TL--------KVYDKPSKPEGPVIMREISRESVTIE 1686 L K Y KP + ++E +ES T E Sbjct: 2251 ELVVEEIVGTKAYRKPEWVQHMEELKEALQESSTEE 2286 >UniRef50_A7RGM0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 621 Score = 155 bits (376), Expect = 1e-35 Identities = 164/651 (25%), Positives = 271/651 (41%), Gaps = 65/651 (9%) Query: 757 QVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 ++ G P+P I W K++KPVK + D HS+TI+ D YT KA N G Sbjct: 1 KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASP-DDTAKYTCKATNKSGT 59 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + + + P +P +N EI V E +++L ++ P + WY+++ ++ Sbjct: 60 TTRNINVDISAPII--IKP---LN--DEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLL 112 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 E I + DG+ L+I + + + D +YKCV +N AG + I E F K Sbjct: 113 EEDERIMYDTDGDQHTLIIQSAELD-DEAEYKCVVTNIAGSVDVKTELIIAPE---FQKE 168 Query: 934 LQKS-YETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXX 990 +KS ++ G V L+ + T +W+ + K + G E+ + Sbjct: 169 PEKSTFDVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGK 228 Query: 991 XXDVGVIKCIVKD---QETSTMLV-VKETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D G + + ++T T V +K PEF +K+Q +V E D + E Sbjct: 229 PDDSGKYTVVAESPAGRDTRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE--------- 279 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV 1102 +G + ++ G + L I N D G Y C ++ + AE+ + Sbjct: 280 -----EGRFLIVD------DEEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQI 328 Query: 1103 VEL--PPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDG 1158 EL PE Q + + + T E+ +T K V W KD + + I + G Sbjct: 329 EELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKG 388 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVEE-PSINFTLRLPEFILVPANTD 1213 + I +D+G Y CE N + T I+ VEE P I +L+ E + Sbjct: 389 DSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEEL---EGNP 445 Query: 1214 AYLTVEIPDETLDVT-WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 LT + V W+K + + DT+++ I + TLII+ DD Y CV + Sbjct: 446 VTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASN 505 Query: 1273 --AKSTTK--LKVEVVEFPPKIVDYEREYRI--KRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 K T + LKV FPP+I ER +I ++ + V P+P+ +W + K Sbjct: 506 QVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGK 565 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 I++ + +L I E DAG Y +N G + ++V I Sbjct: 566 PIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI 616 Score = 147 bits (356), Expect = 3e-33 Identities = 154/576 (26%), Positives = 232/576 (40%), Gaps = 59/576 (10%) Query: 639 KPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 KP +D EG + LEC + P+ + W + DE I + D H L Sbjct: 75 KPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQH----TLI 130 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILS 755 I + + E Y V N G + L I P EP KS V G+ V L Sbjct: 131 IQSAELDDEAEYKCVVTNIAGSVDVKTELIIA-----PEFQKEPEKSTFDVNTGDDVSLD 185 Query: 756 AQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 V G P P + W K++KPVK L K+ D HS+ I K K D G YT+ AE+ G Sbjct: 186 LTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKI-KGGKPDDSGKYTVVAESPAG 244 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + + ++ E P F + Q + V E G K VA R Sbjct: 245 RDTRTYEVNIK------GEKPEFKQKMQPLQVLE-GDEK-VAEEGRF------------- 283 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--F 930 I + +G+ L+I N +DSG Y C A+N GK++ A + I+ V F Sbjct: 284 -----LIVDDEEGDLFSLIIGNA-KPLDSGVYICQATNDTGKATAEAEIQIEELLVAPEF 337 Query: 931 VKH--LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 + Q + ++ T+ L W + K ++ D I +G Sbjct: 338 AEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMA 397 Query: 989 XXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D G KC K++ T T +V E PE LQ+ E E + L + A Sbjct: 398 VTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFTGTPA 457 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVT 1101 V ++Y+F + G L I+ T D+ Y C+ ++ +C ++ Sbjct: 458 PVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLK 517 Query: 1102 VVE--LPPEIITRLQNQKVNKGNKATFEIELT-KGDAL--VRWFKDGSEIQFSNHIQLTI 1156 V E PPEI + +K+ K I +T G+ V+WFKDG I+ S+ + + Sbjct: 518 VTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRP 577 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 G L I+ + +DAG Y+CE N T+ T++ Sbjct: 578 RGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTID 613 Score = 126 bits (304), Expect = 7e-27 Identities = 127/543 (23%), Positives = 214/543 (39%), Gaps = 35/543 (6%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPS 1195 ++WFKD ++ S I++ L I DD +Y+C+ N T + + S Sbjct: 10 IQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVDIS 69 Query: 1196 INFTLR-LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 ++ L + I V L I V WYK ++E+ E+ +D + TL Sbjct: 70 APIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQHTL 129 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQ 1312 II+ DD+ EY CV+ + + +K E++ P + E+ + + G DV+L + Sbjct: 130 IIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTGDDVSLDLTVT 189 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 P P EW + K +K + + SL IK + D+G Y + E+ G Sbjct: 190 GKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDTRT 249 Query: 1373 MNVTIL-DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 V I +KP K L++ + +E + +V+ +E D I Sbjct: 250 YEVNIKGEKPEFKQKMQPLQVLEGDEKVA-EEGR--------FLIVDDEEGDLFSLI--- 297 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 I N K S + A N+ T E I+E + E+ + Sbjct: 298 --------IGNAKPLDSGVYICQATNDT----GKATAEAEIQIEELLVAPEFAEEEATQL 345 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATYENRXXX---XXXXXXXXXXXX 1547 T ++D+ L G P+P+V W +D K L + + +++ Sbjct: 346 TLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGT 405 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 YKC A N G + +V +++ P IT S +++++ G+ +T G P P W+ Sbjct: 406 YKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELE--GNPVTLTCKFTGTPAPVAEWF 463 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 K L + Y + + + IK R Y ASN G + LKV +K Sbjct: 464 KASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGDLKVTEKMF 523 Query: 1668 KPE 1670 PE Sbjct: 524 PPE 526 Score = 121 bits (291), Expect = 3e-25 Identities = 140/641 (21%), Positives = 255/641 (39%), Gaps = 57/641 (8%) Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-VE 1104 ++ W +D + +KP + K + R I L I S D +Y+C ++S T + V+ Sbjct: 9 EIQWFKDDKPVKPSQ-KIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRNINVD 67 Query: 1105 LPPEIITRLQNQKVN--KGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 + II + N +++ +G+ E ++ G DA V W+KD ++ I DG + Sbjct: 68 ISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYDTDGDQH 127 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT--DAYLTVE 1219 L I +LDD EY C V N + + E + PE NT D L + Sbjct: 128 TLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVNTGDDVSLDLT 187 Query: 1220 IPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 + + T V W+K ++ T + + + + +L I+ DD +YT V + T Sbjct: 188 VTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLKIKGGKPDDSGKYTVVAESPAGRDT 247 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 +V + P+ + ++ G + + + F +DE Sbjct: 248 RTYEVNIKGEKPEFKQKMQPLQVLEGDEK--VAEEGRFLIVDDE---------------- 289 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 + SL I + D+G+Y + N+ G A E + I + P E +++ Sbjct: 290 --EGDLFSLIIGNAKPLDSGVYICQATNDTGKATAEAEIQIEELLVAP---EFAEEEATQ 344 Query: 1397 INICWDEPEN-----TGN-STIIYYVVEYQEIDTTEWISVKNITKTQ-TSIQNLKTNSSY 1449 + + D+ TG +++ + + + + I + + + I + N S Sbjct: 345 LTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSG 404 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 ++ A N+ ++ T + V E ++P + + L+ + + LTC F G P Sbjct: 405 TYKCEAKNKAGVN-----TRTFIVNVE---EAPEITESLQEMEELEGNPVTLTCKFTGTP 456 Query: 1510 QPKVTWYRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 P W++ L T YE + YKC+A N G+V Sbjct: 457 APVAEWFKASTPL-TDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCRGD 515 Query: 1565 VGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + + +K P IT K +E ++ I G P P+V W+K+G + NI Sbjct: 516 LKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNI 575 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + T + I + + YT EA N GTSS + +++ Sbjct: 576 RPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDVQI 616 Score = 118 bits (285), Expect = 1e-24 Identities = 142/652 (21%), Positives = 248/652 (38%), Gaps = 62/652 (9%) Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 ++ P+P+I W + + P + I V D+H L I YT A N+ Sbjct: 1 KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHS----LTIVGASPDDTAKYTCKATNK 56 Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNN-- 772 G + I + I P +I+PL I V +G+SV L + G P + W K++ Sbjct: 57 SGTTTRNINVDISA-----PIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYL 111 Query: 773 -KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + + + +DGD H++ I++ ++ DE Y N G + + + ++ E Sbjct: 112 LEEDERIMYDTDGDQHTL-IIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPE 170 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 F V + L VT P P + W+++++ + + + + L Sbjct: 171 KSTF-------DVNTGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTRRLEVKAKDDEHSLK 223 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 I + DSG Y VA + AG+ + V I EK F + +Q + EG + E Sbjct: 224 IKGGKPD-DSGKYTVVAESPAGRDTRTYEVNIKGEKPEFKQKMQ-PLQVLEGDEKVAEEG 281 Query: 952 TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTM- 1009 V +EG D GV C D +T Sbjct: 282 RFLIVDD------------------EEGDLFSLIIGNAKPLDSGVYICQATNDTGKATAE 323 Query: 1010 --LVVKETI--PEFI-RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKY 1063 + ++E + PEF + + E D LE+ + + +V W +D + + + ++ Sbjct: 324 AEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPL-TEDDRI 382 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVNK 1120 + +G + I + +D G Y C +++ + + VE PEI LQ + + Sbjct: 383 IIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELE 442 Query: 1121 GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC- 1178 GN T + T A + WFK + + ++ + +G L I DD Y C Sbjct: 443 GNPVTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCV 502 Query: 1179 ---EVGNSKCTAILTVEE----PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 +VG C L V E P I R + +L+ + + DV W+K Sbjct: 503 ASNQVGKVTCRGDLKVTEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKWFK 562 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 I + + + TL I +D YTC + T+ ++V Sbjct: 563 DGKPIRQSSRLNIRPRGDTYTLNIHTTEPEDAGSYTCEAQNKMGTSSTTIDV 614 Score = 99 bits (238), Expect = 7e-19 Identities = 133/552 (24%), Positives = 225/552 (40%), Gaps = 49/552 (8%) Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 ++T P P I W+++++ + PS+ I ++ + L I + D+ Y C A+N +G Sbjct: 1 KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPD-DTAKYTCKATNKSGT 59 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDH 972 ++ + +D+ +K L + EG +V LEC S + WY + + + Sbjct: 60 TTRN--INVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDER 117 Query: 973 REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI-PEFIRKLQD--FEVK 1029 +G D KC+V + S + + I PEF ++ + F+V Sbjct: 118 IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTELIIAPEFQKEPEKSTFDVN 177 Query: 1030 EKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 D L++ + + T V W +D + +K + + + + + L I+ D G+Y+ Sbjct: 178 TGDDVSLDLTVTGKPTPKVEWFKDDKPVKGTR-RLEVKAKDDEHSLKIKGGKPDDSGKYT 236 Query: 1089 CILRD----ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGS 1144 + ++ T EV + PE ++Q +V +G++ E +G L+ ++G Sbjct: 237 VVAESPAGRDTRTYEVNIKGEKPEFKQKMQPLQVLEGDEKVAE----EGRFLIVDDEEGD 292 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLP 1203 FS I G + L D+G Y C+ N T T E E I L P Sbjct: 293 --LFS-----LIIGNAKPL--------DSGVYICQATND--TGKATAEAEIQIEELLVAP 335 Query: 1204 EFILVPANTDAYLTVEIPDETLD--VTWYKKKSV--IEDTEKFT----LISDVKKRTLI- 1254 EF A T L +E D TL+ VT K V +D + T +I D K + I Sbjct: 336 EFAEEEA-TQLTL-IEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDSCIV 393 Query: 1255 -IRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 I T +D Y C + A T+ + VE P+I + +E G+ VTL + Sbjct: 394 DIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEAPEITESLQEMEELEGNPVTLTCKFT 453 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 P P EW S + + + S +L IK D YK N G Sbjct: 454 GTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTLIIKTTVRDDDDTYKCVASNQVGKVTCR 513 Query: 1373 MNVTILDKPSPP 1384 ++ + +K PP Sbjct: 514 GDLKVTEKMFPP 525 Score = 96.3 bits (229), Expect = 8e-18 Identities = 76/300 (25%), Positives = 133/300 (44%), Gaps = 22/300 (7%) Query: 632 IPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 + P F+++ Q + E D+ LE + P+P++ W + + D+ I + + D Sbjct: 333 VAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDNKPLTEDDRIIIDHKGDS-- 390 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 C ++ I V GTY A N+ G + ++ ++ E P++ E L+ M +G Sbjct: 391 -C-IVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVE----EAPEITESLQEMEELEGN 444 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKA 807 V L+ + G P P W K + P+ +GD++++ I+K D+ Y A Sbjct: 445 PVTLTCKFTGTPAPVAEWFKASTPLTDTDRYEFIEEGDSYTL-IIKTTVRDDDDTYKCVA 503 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G + V TE+ P + R ++I + EK + + + NP P + W Sbjct: 504 SNQVGKVTCRGDLKV---TEKMFPPEITRPERTEKIVLLEKEELVINVTILGNPRPDVKW 560 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +++ + I S + G+ L I + E D+G Y C A N G SS TIDV+ Sbjct: 561 FKDGKPIRQSSRLNIRPRGDTYTLNIHTTEPE-DAGSYTCEAQNKMGTSS----TTIDVQ 615 Score = 95.5 bits (227), Expect = 1e-17 Identities = 89/328 (27%), Positives = 152/328 (46%), Gaps = 47/328 (14%) Query: 504 EEQSMAPIFVEKLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYD 561 EE +AP F E+ + T + + E V G P+P++ W + KP ++D ++ D Sbjct: 329 EELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVHWTKDN---KPLTEDDRIIID 385 Query: 562 DDNVATLV-IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620 + +V I V P D+GT+ C AKN AG +T IV + E+T Sbjct: 386 HKGDSCIVDIMAVTPNDSGTYKCEAKNKAGV--NTRTFIVNV---EEAPEIT-------- 432 Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 + LEG P T L C+ P P W FK + D + Sbjct: 433 ESLQEMEELEGNPVT-----------------LTCKFTGTPAPVAEW-FKASTPLTDTDR 474 Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP 740 IE + Y ++K T + + TY VA N+ G+ + LK+ T + PP++ P Sbjct: 475 YEFIE-EGDSYTLIIKTT--VRDDDDTYKCVASNQVGKVTCRGDLKV-TEKMFPPEITRP 530 Query: 741 --LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPK 795 + +++ + E ++++ ++GNPRP + W K+ KP++ L + GDT+++ I Sbjct: 531 ERTEKIVLLEKEELVINVTILGNPRPDVKWFKDGKPIRQSSRLNIRPRGDTYTLNI-HTT 589 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVE 823 + +D G YT +A+N G + T+ + +E Sbjct: 590 EPEDAGSYTCEAQNKMGTSSTTIDVQIE 617 Score = 56.4 bits (130), Expect = 8e-06 Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 6/158 (3%) Query: 1507 GVPQPKVTWYRDGKKLKTA---KATY-ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 G P+P++ W++D K +K + + Y ++ Y C A N G + Sbjct: 4 GEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTTRN 63 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 V I +I N++I GD + VI G P +V+WYK+ LE D+ Sbjct: 64 INVDISAPIIIKPLNDEIDVLE--GDSVRLECVISGGPDAQVLWYKDDYLLEEDERIMYD 121 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 T + I+ + ++Y +N AG+ V+ L Sbjct: 122 TDGDQHTLIIQSAELDDEAEYKCVVTNIAGSVDVKTEL 159 Score = 55.6 bits (128), Expect = 1e-05 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%) Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 ++ G P+P+I WF+ +KPSQ ++ Y DD + +L I P+D +TC A N +G Sbjct: 1 KITGEPKPEIQWFKDDKPVKPSQKIRVDYRDD-IHSLTIVGASPDDTAKYTCKATNKSGT 59 Query: 592 ASSTTELIVEAPL 604 + + + AP+ Sbjct: 60 TTRNINVDISAPI 72 Score = 55.6 bits (128), Expect = 1e-05 Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Query: 509 APIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 API ++ L + +G +V+ EC + G P Q+ W++ +++ + MY D + T Sbjct: 70 APIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERI-MYDTDGDQHT 128 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L+I+ +D + CV N AG TELI+ Sbjct: 129 LIIQSAELDDEAEYKCVVTNIAGSVDVKTELII 161 Score = 54.0 bits (124), Expect = 4e-05 Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 2/143 (1%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAV-IEGIPPPEVI 1605 Y C A ND G+ + I++ V + E+ Q + D+ + + + G P PEV Sbjct: 309 YICQATNDTGKATAEAEIQIEELLVAPEFAEEEATQLTLIEDDDMTLELHVTGKPKPEVH 368 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W K+ L D I K + ++ I + + S Y EA N AG ++ + V + Sbjct: 369 WTKDNKPLTEDDRIIIDHKGDSCIVDIMAVTPNDSGTYKCEAKNKAGVNTRTFIVNVEEA 428 Query: 1666 PSKPEGPVIMREISRESVTIEWK 1688 P E M E+ VT+ K Sbjct: 429 PEITESLQEMEELEGNPVTLTCK 451 Score = 51.2 bits (117), Expect = 3e-04 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 G PRP + WF+ I+ S + D TL I PEDAG++TC A+N G +S+ Sbjct: 552 GNPRPDVKWFKDGKPIRQSSRLNIRPRGDTY-TLNIHTTEPEDAGSYTCEAQNKMGTSST 610 Query: 595 TTELIVEAPLS 605 T ++ +E +S Sbjct: 611 TIDVQIEGEVS 621 Score = 49.2 bits (112), Expect = 0.001 Identities = 49/192 (25%), Positives = 91/192 (47%), Gaps = 18/192 (9%) Query: 434 DEAINLVEGE--RLYILDTSNQD---WWYVQKHLTEEKGWVPAQYLMDENNYTQYLQK-K 487 ++ I+++EG+ RL + + D WY +L EE + Y D + +T +Q + Sbjct: 78 NDEIDVLEGDSVRLECVISGGPDAQVLWYKDDYLLEEDERI--MYDTDGDQHTLIIQSAE 135 Query: 488 LNEKIDKLPVFEK-----PTSEEQSMAPIFVEKLRPKHTPD---GSTVQFECQVEGYPRP 539 L+++ + V E +AP F +K K T D G V + V G P P Sbjct: 136 LDDEAEYKCVVTNIAGSVDVKTELIIAPEF-QKEPEKSTFDVNTGDDVSLDLTVTGKPTP 194 Query: 540 QITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 ++ WF+ +K ++ ++ DD +L I+ P+D+G +T VA++ AG + T E+ Sbjct: 195 KVEWFKDDKPVKGTRRLEVKAKDDE-HSLKIKGGKPDDSGKYTVVAESPAGRDTRTYEVN 253 Query: 600 VEAPLSDHGSEM 611 ++ + +M Sbjct: 254 IKGEKPEFKQKM 265 Score = 41.5 bits (93), Expect = 0.25 Identities = 38/168 (22%), Positives = 74/168 (44%), Gaps = 12/168 (7%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654 I G P PE+ W+K+ ++ ++ + ++ + I ++KYT +A+N +GT+ Sbjct: 2 ITGEPKPEIQWFKDDKPVKPSQKIRVDYRDDIHSLTIVGASPDDTAKYTCKATNKSGTTT 61 Query: 1655 ---SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 +V+++ + KP E V+ + R I P + Y +E+ E Sbjct: 62 RNINVDISAPIIIKPLNDEIDVLEGDSVRLECVISGGPDAQVLWYK-DDYLLEEDER--- 117 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 + D D D T IQ + E ++ + N G S +++E I+ Sbjct: 118 ---IMYDTDGDQHTLIIQSAELDDEAEYKCVVTNIAG-SVDVKTELII 161 >UniRef50_Q0E8J3 Cluster: CG33484-PD, isoform D; n=9; Sophophora|Rep: CG33484-PD, isoform D - Drosophila melanogaster (Fruit fly) Length = 3651 Score = 153 bits (372), Expect = 4e-35 Identities = 137/536 (25%), Positives = 230/536 (42%), Gaps = 69/536 (12%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 Q L D+ + + + + + + I +F +E + +P+F L+ + +G FEC Sbjct: 1343 QTLRDQVDQQRIVTENIRKDIQVNSIF----TELRYASPLFTRPLKDAVSREGDRFVFEC 1398 Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 +V G P P + WF+ I+ + D++ +D + LVI E F D+ F+C A N G Sbjct: 1399 EVTGTPEPAVEWFKDGISIQTNSDYKTTFDK-GICRLVIEETFAADSARFSCRASNLVGT 1457 Query: 592 ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 + L V ++ +E+ + +PP + ++ EGS Sbjct: 1458 CDTNATLSVR----ENAAEVQL------------------VPPRILRFLQSGKATEGSSF 1495 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 C + +P P + W FK ++ + D V ++ + LK V + YT Sbjct: 1496 QFACVVAGVPLPTVQW-FKNDKCIDDSPDYVISYNNGE---ATLKFEEVFLEDDAVYTCS 1551 Query: 712 AVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A N G L ++ E E P PL + + R G+ + L A V G PRP + W Sbjct: 1552 ASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLH 1611 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEE--PTE 827 N KP + P S + +T++ P+ D G Y L A+N G A TS + V+ P E Sbjct: 1612 NGKPFQ--PRDSKYEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNE 1669 Query: 828 -------ENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + EP P +++++ E ++L + P P + WY N + S Sbjct: 1670 TSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESAD 1729 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI------------DVE 926 + F G+ L+I V E D+G YK VA NSAG++S + + E Sbjct: 1730 VQLLFQGDRCSLIIQEVYQE-DAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQAE 1788 Query: 927 KVTFVKHLQKSYE-------TEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHR 973 + + K Q +E +EG+ V+LE Q S ++ +W+ KE+ +D R Sbjct: 1789 RQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQ-LDQR 1843 Score = 144 bits (348), Expect = 3e-32 Identities = 200/791 (25%), Positives = 313/791 (39%), Gaps = 121/791 (15%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPD------------GSTVQFECQVEGYPRPQITWFRQTA 548 P E A + VE L P P G ++ E V G PRP++ W Sbjct: 1555 PAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNG- 1613 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608 KP Q Y+ V TL+I + +P DAG++ AKN AG A ++ +IV+ L + Sbjct: 1614 --KPFQPRDSKYEYGRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNET 1670 Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 S+ + A +E I P K + EG + L+C +V PEP++ W Sbjct: 1671 SDSEM------------ASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWY 1718 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 + ++ + + D CS++ I V + G Y VVA+N GEAS LK+ Sbjct: 1719 HNERPVKESADVQLLFQGDR---CSLI-IQEVYQEDAGHYKVVAINSAGEASSSCELKVT 1774 Query: 729 T-GEKEP-----------PQVIEP-----LKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 + EP P+ +P L ++ +GE V+L Q G+ T W Sbjct: 1775 PLNQAEPATRAQAERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLT 1834 Query: 772 NKPVKA---LPTKSDGDTHSIT-ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE---- 823 NK ++ + T+SD + IL D+GVYT+K N G A+ + + V+ Sbjct: 1835 NKELQLDQRITTQSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNA 1894 Query: 824 -EPTEENAEPPLFINR-----FQEITVKEKG----TIKLVARVTRNPVPSITWYRNNEII 873 E + I R F+E+ ++G IK V P P + W+ N++ + Sbjct: 1895 PENRRSSQSSVEIIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPV 1954 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTF 930 + GE L I + + G CVA N AGK++ A + I + + Sbjct: 1955 HGHNFLVST-SGERQVLTIQKLTHDA-VGKISCVAENEAGKATCVAFLNIRGSGLPASSD 2012 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS-------------TKWYHNKKEIS------GMD 971 V+ + + + TE + V ++ QT T S T+ +H+ I G Sbjct: 2013 VQTVSQEHNTESSR-VTIKKQTFTTTSTSQVNSYEGNAPQTEVHHSSAHIDQSLKQLGQQ 2071 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK 1031 EI++ K Q + IP+ +L+ E+ + Sbjct: 2072 RPEIVESHHYQELHKSKEMSSPTVQQKSFSFIQSSGANGQSAVAIPDSPTRLRR-EIAPR 2130 Query: 1032 DVAILEVEINSETADVVWER--DG---EIIKPKKNKYDFEKRGHIR--------KLYIRN 1078 L +I + ADV E DG IK +KN + H R + ++ Sbjct: 2131 FTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQ 2190 Query: 1079 TSVHDEGEY----SCILRDESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIELT- 1131 V D G Y S + + TA++ V + PP RLQ Q KG K T E+E+T Sbjct: 2191 VGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTG 2250 Query: 1132 KGDALVRWFKDGSEIQ---FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSK 1184 + V W KD ++ S H +L G +L I D+G+Y G +K Sbjct: 2251 LPEPTVTWLKDDKPLKDAGISEH-RLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAK 2309 Query: 1185 CTAILTVEEPS 1195 A + EPS Sbjct: 2310 SIADCAILEPS 2320 Score = 99.1 bits (236), Expect = 1e-18 Identities = 147/637 (23%), Positives = 240/637 (37%), Gaps = 90/637 (14%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F++ K EG + EC + PEP + W G I + + + + C Sbjct: 1377 PLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGI---CR 1433 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE----PPQVIEPLKSMIVRQG 749 L I ++ A N G L ++ E PP+++ L+S +G Sbjct: 1434 -LVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEG 1492 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKA 807 S + V G P PT+ W KN+K + P + LK ++V +D+ VYT A Sbjct: 1493 SSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSA 1552 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N GI SA + V EP E E P F + IKL A V P P + W Sbjct: 1553 SNPAGIEHCSASLIV-EPLEP-TELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWL 1610 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---- 923 N + P ++ ++ + L+I D+G Y A N AG++ V + Sbjct: 1611 HNGKPFQPRDS---KYEYGRVTLIIPQAYPN-DAGSYVLSAKNLAGEAYTSCNVIVKGRL 1666 Query: 924 -----------DVEKVTFVKHLQ-KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969 D+E + HL K EGK V L+C + WYHN++ + Sbjct: 1667 PNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKE 1726 Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCI------------------VKDQETST--- 1008 +++ +G D G K + + E +T Sbjct: 1727 SADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEASSSCELKVTPLNQAEPATRAQ 1786 Query: 1009 ---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVVW-ERDGEIIKPKKNKY 1063 + K++ P+F R L D E + +LEV+ + + W + E+ ++ Sbjct: 1787 AERQSLPKDSQPKFERLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITT 1846 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEVTV--VELPP---------E 1108 + + KL + N S D+G Y+ + D C + + V V P E Sbjct: 1847 QSDSELGVFKLILNNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVE 1906 Query: 1109 IITRLQNQKVNK--GNKATFEIELTKGDALVR--------WFKDGSEIQFSNHIQLTIDG 1158 II R Q + + +K E+ K + +V+ WF + + N + ++ G Sbjct: 1907 IIERHQCPEFKELFSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFL-VSTSG 1965 Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191 ++Q L I D G+ SC E G + C A L + Sbjct: 1966 ERQVLTIQKLTHDAVGKISCVAENEAGKATCVAFLNI 2002 Score = 95.1 bits (226), Expect = 2e-17 Identities = 99/384 (25%), Positives = 156/384 (40%), Gaps = 43/384 (11%) Query: 469 VPAQYLMDENNYTQYLQKKLNEKIDKLPVFEK---PTSEEQSMAPIFVEKLRPK-HTP-- 522 +P Y D +Y + E V K P S +E ++P H P Sbjct: 1632 IPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLK 1691 Query: 523 -----DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 +G V+ +C + G P P++ W+ +K S D Q+ + D +L+I+EV+ ED Sbjct: 1692 DVSIFEGKPVRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDR-CSLIIQEVYQED 1750 Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 AG + VA N+AG ASS+ EL V PL+ + + P F Sbjct: 1751 AGHYKVVAINSAGEASSSCELKV-TPLNQ--------AEPATRAQAERQSLPKDSQPKFE 1801 Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 + DEG ++LE + W +E+ D+ I+ +S++ ++ +L Sbjct: 1802 RLLSDVLADEGEQVVLEVQASGDQPLTAQWFLTNKELQLDQRITTQSDSELGVFKLIL-- 1859 Query: 698 TNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGE-----KEPPQVIE-----PLKSM 744 NV +G YTV N G+A S IV + E + ++IE K + Sbjct: 1860 NNVSGDDKGVYTVKVTNPAGDAKCFSHLIVKSVNAPENRRSSQSSVEIIERHQCPEFKEL 1919 Query: 745 IV-RQGE--SVI-LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVK 798 +QGE VI V G P P + W N++PV + G+ +TI K Sbjct: 1920 FSDKQGEIDEVIKFECIVKGKPTPKVHWFFNDQPVHGHNFLVSTSGERQVLTIQKLTH-D 1978 Query: 799 DEGVYTLKAENSEGIAETSAVITV 822 G + AEN G A A + + Sbjct: 1979 AVGKISCVAENEAGKATCVAFLNI 2002 Score = 79.0 bits (186), Expect = 1e-12 Identities = 51/205 (24%), Positives = 100/205 (48%), Gaps = 11/205 (5%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P F+ + VD+G+D+ +E P P+I G ++ D + ++ + + Sbjct: 2127 IAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNR--- 2183 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +++ V G Y V A N G+++ L +K PP L++ + ++GE Sbjct: 2184 -VTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVKK-TIFPPVFGRRLQAQVSKKGEK 2241 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITILKPKKVKDEGVYTLK 806 + + +V G P PT+TW K++KP+K + G+++ + I++ + D G Y ++ Sbjct: 2242 LTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL-IIEKAQTTDSGKYMVR 2300 Query: 807 AENSEGIAETSAVITVEEPTEENAE 831 A N+ G A++ A + EP+ E + Sbjct: 2301 ATNAGGEAKSIADCAILEPSPERLQ 2325 Score = 75.8 bits (178), Expect = 1e-11 Identities = 87/403 (21%), Positives = 157/403 (38%), Gaps = 30/403 (7%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P+P EW + I+ K + D L I++ D+ + R N G D Sbjct: 1404 PEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNAT 1463 Query: 1375 VTILDKPS-----PPGKPNILEIDSSSINICWDEP---ENTGNSTIIYYVVEYQEIDTTE 1426 +++ + + PP L+ ++ + T+ ++ + D+ + Sbjct: 1464 LSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPD 1523 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 ++ N + + + + A N I S + + ++ T++ P+ + Sbjct: 1524 YVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASL-IVEPLEPTEL--PSFKV 1580 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXX 1545 PL N + I+L I GG+P+P+V W +GK + + YE R Sbjct: 1581 PLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDA 1640 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQK-PVITISNE---DIKQ-KHKV-----------GDE 1589 Y A N GE TSC V ++ + P T +E DI+ K V G Sbjct: 1641 GSYVLSAKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKP 1700 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + VI G P PEVIWY N ++ + + + + I+E+ + + Y + A N Sbjct: 1701 VRLDCVIVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAIN 1760 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 +AG +S LKV P P + R+S+ + +P + Sbjct: 1761 SAGEASSSCELKV--TPLNQAEPATRAQAERQSLPKDSQPKFE 1801 Score = 70.9 bits (166), Expect = 4e-10 Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 12/207 (5%) Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATY 1529 + E + SP +PLK+ + + C G P+P V W++DG ++T K T+ Sbjct: 1368 IFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTF 1427 Query: 1530 ENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIKQ----- 1582 + + C A N G +T+ + +++ + + I + Sbjct: 1428 DKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSG 1487 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + V+ G+P P V W+KN +++ +Y I+ + ++ +E+ + Sbjct: 1488 KATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 1547 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKP 1669 YT ASN AG +L V +P +P Sbjct: 1548 YTCSASNPAGIEHCSASLIV--EPLEP 1572 Score = 69.7 bits (163), Expect = 8e-10 Identities = 93/408 (22%), Positives = 171/408 (41%), Gaps = 39/408 (9%) Query: 1001 VKDQETSTMLVVKETIPEF---IRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 +++Q T L ++ E I+ L+D +E++V + I E + E + I + Sbjct: 1263 IREQATREQLAREQAAREEELRIQSLRDIARREEEVRLQN--IRDEETRIRREEEERIRR 1320 Query: 1058 PKKNKYDFEKRGHIRKLYI-RNTSVHDEGEYSCIL-----RDESCTAEVTVVELPPEIIT 1111 +++ E+ I++ I R ++ D+ + I+ +D + T + + T Sbjct: 1321 ENESRSKREEEARIQREEITRLQTLRDQVDQQRIVTENIRKDIQVNSIFTELRYASPLFT 1380 Query: 1112 R-LQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 R L++ +G++ FE E+T + V WFKDG IQ ++ + T D +L I + Sbjct: 1381 RPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETF 1440 Query: 1170 LDDAGEYSCE----VGNSKCTAILTVEEPSINFTL---RLPEFILVPANTD------AYL 1216 D+ +SC VG A L+V E + L R+ F+ T+ A + Sbjct: 1441 AADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKATEGSSFQFACV 1500 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS- 1275 +P T V W+K I+D+ + + + + TL + +D YTC + Sbjct: 1501 VAGVPLPT--VQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAVYTCSASNPAGI 1558 Query: 1276 ---TTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + L VE +E P ++ ++ + G + L P+P W+ N K + Sbjct: 1559 EHCSASLIVEPLE-PTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQ 1617 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + +K + +L I + DAG Y L +N G A NV + Sbjct: 1618 P-RDSK--YEYGRVTLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIV 1662 Score = 68.5 bits (160), Expect = 2e-09 Identities = 107/435 (24%), Positives = 174/435 (40%), Gaps = 55/435 (12%) Query: 996 VIKCIVKD-QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG 1053 V + I KD Q S ++ P F R L+D +E D + E E+ V W +DG Sbjct: 1355 VTENIRKDIQVNSIFTELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDG 1414 Query: 1054 EIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-------- 1102 I+ + K F+K I +L I T D +SC + +C T+ Sbjct: 1415 ISIQTNSDYKTTFDKG--ICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVRENAAE 1472 Query: 1103 VEL-PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159 V+L PP I+ LQ+ K +G+ F + G L V+WFK+ I S ++ + Sbjct: 1473 VQLVPPRILRFLQSGKATEGSSFQFAC-VVAGVPLPTVQWFKNDKCIDDSPDYVISYNNG 1531 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGN----SKCTAILTVE--EPSINFTLRLPEFILVPANTD 1213 + LK + L+D Y+C N C+A L VE EP+ LP F + +N Sbjct: 1532 EATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPT-----ELPSFKVPLSNAM 1586 Query: 1214 AYLTVEIPDETL-------DVTWYKKKSVIEDTE------KFTLI------SDVKKRTLI 1254 A + +I E + +V W + + + TLI +D L Sbjct: 1587 ARVGQKIKLEAIVGGIPRPEVYWLHNGKPFQPRDSKYEYGRVTLIIPQAYPNDAGSYVLS 1646 Query: 1255 IRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 + + + L + S +++ ++ P + ++ I G V L Sbjct: 1647 AKNLAGEAYTSCNVIVKGRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCV 1706 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA- 1369 P+P W N + +K+ + SL I++V DAG YK+ N+ G A Sbjct: 1707 IVGQPEPEVIWYHNERPVKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINSAGEAS 1766 Query: 1370 -DVEMNVTILDKPSP 1383 E+ VT L++ P Sbjct: 1767 SSCELKVTPLNQAEP 1781 Score = 58.8 bits (136), Expect = 2e-06 Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 1/93 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F+ L+ G T +FEC V+ +P+PQ+ W +++ + Y + V L Sbjct: 3553 PLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHNGGLLESGSRHCIEY-RNGVCRLT 3611 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + + +P+D G++ C A N G A+++ L V + Sbjct: 3612 LPQAYPDDNGSYACTAINPLGAATTSGNLTVSS 3644 Score = 52.4 bits (120), Expect = 1e-04 Identities = 83/398 (20%), Positives = 148/398 (37%), Gaps = 46/398 (11%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 TE PLF ++ +E VT P P++ W+++ I + FD Sbjct: 1370 TELRYASPLFTRPLKDAVSREGDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDK 1429 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-----DVEKV--TFVKHLQKSY 938 LVI + DS + C ASN G A +++ +V+ V ++ LQ Sbjct: 1430 GICRLVIEETFA-ADSARFSCRASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGK 1488 Query: 939 ETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 T EG + C + + +W+ N K I I D V Sbjct: 1489 AT-EGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVISYNNGEATLKFEEVFLEDDAV 1547 Query: 997 IKCIVKD----QETSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADV 1047 C + + S L+V+ +P F L + + LE + +V Sbjct: 1548 YTCSASNPAGIEHCSASLIVEPLEPTELPSFKVPLSNAMARVGQKIKLEAIVGGIPRPEV 1607 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEY-------------SC----- 1089 W +G+ +P+ +KY++ G + L I +D G Y SC Sbjct: 1608 YWLHNGKPFQPRDSKYEY---GRV-TLIIPQAYPNDAGSYVLSAKNLAGEAYTSCNVIVK 1663 Query: 1090 -ILRDESCTAEVT--VVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSE 1145 L +E+ +E+ + + P + L++ + +G + + + + + V W+ + Sbjct: 1664 GRLPNETSDSEMASDIEPIKPAVHLPLKDVSIFEGKPVRLDCVIVGQPEPEVIWYHNERP 1723 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++ S +QL G + L I + +DAG Y NS Sbjct: 1724 VKESADVQLLFQGDRCSLIIQEVYQEDAGHYKVVAINS 1761 Score = 50.0 bits (114), Expect = 7e-04 Identities = 26/100 (26%), Positives = 49/100 (49%), Gaps = 2/100 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 GD ++ + G P P V W+K+G ++ + +Y T + + I+E + S++++ Sbjct: 1391 GDRFVFECEVTGTPEPAVEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCR 1450 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE--GPVIMREISRESVT 1684 ASN GT TL V + ++ + P I+R + T Sbjct: 1451 ASNLVGTCDTNATLSVRENAAEVQLVPPRILRFLQSGKAT 1490 Score = 48.4 bits (110), Expect = 0.002 Identities = 35/179 (19%), Positives = 75/179 (41%), Gaps = 7/179 (3%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536 +P PL + D+ + I+ G P P++ ++G +L T + NR Sbjct: 2128 APRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIE 2187 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAV 1595 Y A N G+ ++ + +++ + ++ Q K G++ + Sbjct: 2188 LKQVGVGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVE 2247 Query: 1596 IEGIPPPEVIWYKNGNKLEND--KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + G+P P V W K+ L++ E+ + + + + I++ + + S KY + A+N G Sbjct: 2248 VTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGG 2306 Score = 48.4 bits (110), Expect = 0.002 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 3/111 (2%) Query: 1275 STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 ST L V+ FPP + K+G +T+ V+ P+P W+ + K +K + Sbjct: 2212 STADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGIS 2271 Query: 1335 KPSI--DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + S L I+K + TD+G Y +R N G A + IL+ PSP Sbjct: 2272 EHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILE-PSP 2321 Score = 46.4 bits (105), Expect = 0.009 Identities = 30/103 (29%), Positives = 50/103 (48%), Gaps = 3/103 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + + A+ +G P PE+ KNG +L D I+ K I +K++ + +Y + Sbjct: 2143 GADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRYAVT 2202 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIE 1686 ASNT G S+ L V P G + ++S+ E +T+E Sbjct: 2203 ASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTME 2245 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 + PT + +AP F L K G+ V E +G+P P+I + + ++ Sbjct: 2118 DSPTRLRREIAPRFTTPLSGKIVDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRI 2177 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + N T+ +++V DAG + A N G ++ST +L+V+ Sbjct: 2178 -SNKCNRVTIELKQVGVGDAGRYAVTASNTVGQSTSTADLVVK 2219 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/103 (24%), Positives = 44/103 (42%), Gaps = 1/103 (0%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATL 568 P+F +L+ + + G + E +V G P P +TW + +K + N L Sbjct: 2225 PVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVTWLKDDKPLKDAGISEHRLLAQGNSYRL 2284 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 +I + D+G + A NA G A S + + P + E+ Sbjct: 2285 IIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPERLQEV 2327 Score = 41.1 bits (92), Expect = 0.33 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 PLFI ++I V GT + V +P P + W N ++ + L + Sbjct: 3553 PLFITPLKDIAVGVGGTARFECIVQAHPQPQVNWTHNGGLLESGSRHCIEYRNGVCRLTL 3612 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + D+G Y C A N G ++ +T+ Sbjct: 3613 PQAYPD-DNGSYACTAINPLGAATTSGNLTV 3642 Score = 37.9 bits (84), Expect = 3.0 Identities = 36/169 (21%), Positives = 60/169 (35%), Gaps = 11/169 (6%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------LDAKSTTKLK 1280 V W+K I+ + D L+I + D ++C D +T ++ Sbjct: 1408 VEWFKDGISIQTNSDYKTTFDKGICRLVIEETFAADSARFSCRASNLVGTCDTNATLSVR 1467 Query: 1281 ---VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 EV PP+I+ + + + GS P P +W N K I S Sbjct: 1468 ENAAEVQLVPPRILRFLQSGKATEGSSFQFACVVAGVPLPTVQWFKNDKCIDDSPDYVIS 1527 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPP 1384 ++ A+L ++V D +Y N G H + V L+ P Sbjct: 1528 YNNGEATLKFEEVFLEDDAVYTCSASNPAGIEHCSASLIVEPLEPTELP 1576 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/86 (24%), Positives = 39/86 (45%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + +G+DV++ Y FP P + N + + HT+ S ++ +K+V DAG Y Sbjct: 2140 VDQGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVGVGDAGRY 2199 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPP 1384 + N G + ++ + PP Sbjct: 2200 AVTASNTVGQSTSTADLVVKKTIFPP 2225 >UniRef50_Q4SLN8 Cluster: Chromosome 15 SCAF14556, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15 SCAF14556, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2646 Score = 152 bits (368), Expect = 1e-34 Identities = 185/765 (24%), Positives = 307/765 (40%), Gaps = 63/765 (8%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIVPDENISVAIES 686 ++ P F+K+ ++Q VDEG D+ L C L + P + W KGE + P + Sbjct: 37 VVNAAPVLFTKELESQTVDEGDDVRLHCEL-SKPAVPLEWK-KGELGLCPCTKYDIKQAG 94 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPI-------VLKIKTGEKEPPQVIE 739 + L I +V G+YT + + A L + +L I + +P Sbjct: 95 TR----ATLVIHDVDPEDSGSYTCDTGDCQSTAQLIVKVPFRNTILLIFSHAAQPVLFKT 150 Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKK 796 L+++ + GES L + P ++ W +K + + + DG T + + K + Sbjct: 151 QLQNLERQAGESASLCCETT-KPGASVVWRHGDKVLSSSSKYRLRQDGSTVELVVYKLQG 209 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVAR 855 D GVY+ G TSAV+TV+E + I +F E V +G ++ Sbjct: 210 -PDAGVYSCDT----GSQRTSAVLTVQEIE-------VSILKFLESCVVSEGEDVRFECL 257 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 V+R P + W + + ++ DG L + V +E DSG + + G Sbjct: 258 VSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGV-TEADSG----TVTFTVGNH 312 Query: 916 SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHRE 974 + A +T+ V F K L+ E EG IL C+TSH S +W ++ D Sbjct: 313 TSTASLTVKAAPVLFKKELENQ-EVLEGDKAILSCETSHPDCSVRWLKGSTVLTHGDKYS 371 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA 1034 I Q D G C D+ +S L V+E + +R+L D V A Sbjct: 372 IEQRATAHTLCIHKLDVKDSGEYTCDTGDKRSSASLTVREHV-RILRELCDVTVTTGQDA 430 Query: 1035 ILEVEINSE--TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 + EVE++ TA W D + N+ E G + +L ++ + + G+ + ++ Sbjct: 431 LFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSE--GRVHRLALKMVTTDESGDVAFVVG 488 Query: 1093 DESCTAEVTVVELP---PEIITR-LQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 D+ A + V E P P + L+NQ +G+ + EL+K V W K G IQ Sbjct: 489 DQKSVACLLVEEKPKGAPVFFRKELKNQDAVEGDDVSLRCELSKPGIRVEWRKGGMVIQP 548 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPE---F 1205 S ++ G Q+L I + +D+G Y+C+ G+ TA L V+ + L F Sbjct: 549 SKKYEMKQKGCVQELCIQNLVSEDSGYYTCDAGDQLTTAALAVQAKEVLIVCGLKTTDVF 608 Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQ 1263 + A L+ P + V W+ + +E + FT I S TL ++ DD Sbjct: 609 VGEWATFSCQLSARAPGK---VQWWLDGTRLE-SSAFTEIGLSQGHIYTLTLKNLAPDDS 664 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPP-KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 V+ A S T +V+ P ++V + + + Y W Sbjct: 665 ---GTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVVENQPAEFICQYSR--PVKARWR 719 Query: 1323 VNSKIIK-KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 N + ++ + D A L I +V D G Y E C Sbjct: 720 KNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYACEAEGTC 764 Score = 128 bits (309), Expect = 2e-27 Identities = 90/338 (26%), Positives = 151/338 (44%), Gaps = 27/338 (7%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F+ +L+ + PDG V F+C V G P P + W++ +++ + + + D + L Sbjct: 1351 APVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQL 1410 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS---DHGSEMTVXXXXXXXXXXXX 625 +I V P D G + C A+N +G S+ EL V+ S D ++ T Sbjct: 1411 IITTVLPTDMGVYRCTAENGSGITSTKAELRVDMSCSSDYDTAADATETSSYVSAKGYIS 1470 Query: 626 AD--ILEGIP-----PTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDIAWLFKGEEIVPD 677 D E + P ++ +V G+ I ++ ++ P+P + W G + Sbjct: 1471 RDTETFESVTEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSS 1530 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PP 735 E I + +E D+H L+I VK+ G Y+ N G A L + ++ PP Sbjct: 1531 ERILLQVERDVHS----LEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPP 1586 Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN--------KP-VKALPTKSDGDT 786 + +E + V+QG S+ LS +V G+P P ++W K KP K S G Sbjct: 1587 RFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHR 1646 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 HS+ IL + G YT A N G + +A + V++ Sbjct: 1647 HSL-ILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDD 1683 Score = 122 bits (293), Expect = 1e-25 Identities = 155/693 (22%), Positives = 271/693 (39%), Gaps = 56/693 (8%) Query: 993 DVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD 1052 D G C D +S LVV F ++L+ V E D L E++ + W++ Sbjct: 19 DSGSYSCCSDDTISSASLVVNAAPVLFTKELESQTVDEGDDVRLHCELSKPAVPLEWKK- 77 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELP------ 1106 GE+ KYD ++ G L I + D G Y+C D TA++ +V++P Sbjct: 78 GELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTAQL-IVKVPFRNTIL 136 Query: 1107 --------PEII-TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTID 1157 P + T+LQN + G A+ E TK A V W + S+ +L D Sbjct: 137 LIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDKVLSSSSKYRLRQD 196 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 G +L +Y DAG YSC+ G+ + +A+LTV+E ++ L+ E +V D Sbjct: 197 GSTVELVVYKLQGPDAGVYSCDTGSQRTSAVLTVQEIEVSI-LKFLESCVVSEGEDVRFE 255 Query: 1218 VEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 + E + +K + V ++D + + SD + +L +R TE D T + + ST Sbjct: 256 CLVSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGVTEADSGTVTFTVGNHTST 315 Query: 1277 TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 L V+ P + E E + D +L + P + W+ S ++ K Sbjct: 316 ASLTVKAA---PVLFKKELENQEVLEGDKAILSCETSHPDCSVRWLKGSTVL--THGDKY 370 Query: 1337 SIDSKSA--SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 SI+ ++ +L I K++ D+G Y C D + ++ + IL Sbjct: 371 SIEQRATAHTLCIHKLDVKDSGEY------TCDTGDKRSSASLTVRE----HVRILR--- 417 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 +C D TG + + + + EW N+ + Q +R Sbjct: 418 ---ELC-DVTVTTGQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSEGRVHRLALK 473 Query: 1455 AVNEVDISDASETTEYYK-----VIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGV 1508 V + D + K +++E +P K LKN +D+ L C Sbjct: 474 MVTTDESGDVAFVVGDQKSVACLLVEEKPKGAPVFFRKELKNQDAVEGDDVSLRCEL-SK 532 Query: 1509 PQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN-DHGEVETSCVVGI 1567 P +V W + G ++ +K YE + + D G+ T+ + + Sbjct: 533 PGIRVEWRKGGMVIQPSK-KYEMKQKGCVQELCIQNLVSEDSGYYTCDAGDQLTTAALAV 591 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLV-TAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKE 1625 Q K V+ + +K EW + + P +V W+ +G +LE+ I ++ Sbjct: 592 QAKEVLIVCG--LKTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQG 649 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + +K L S +A + T+ + V Sbjct: 650 HIYTLTLKNLAPDDSGTVMFKAGSLTSTAKLLV 682 Score = 120 bits (290), Expect = 3e-25 Identities = 188/919 (20%), Positives = 356/919 (38%), Gaps = 73/919 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V EG D+ EC + P + W K +++ +N IESD ++ L+ V + Sbjct: 246 VSEGEDVRFECLVSREEAPLVQW--KLQDVPLQDNQMNVIESDGRLHSLTLR--GVTEAD 301 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 GT T N ASL + +KE L++ V +G+ ILS + +P Sbjct: 302 SGTVTFTVGNHTSTASLTVKAAPVLFKKE-------LENQEVLEGDKAILSCET-SHPDC 353 Query: 765 TITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 ++ W K + + + H++ I K VKD G YT G +SA +T Sbjct: 354 SVRWLKGSTVLTHGDKYSIEQRATAHTLCIHK-LDVKDSGEYTCDT----GDKRSSASLT 408 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V E + ++TV ++ + V + W+ + ++ ++ Sbjct: 409 VREHVR-------ILRELCDVTVTTGQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQM 461 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + +G L + V ++ +SGD V + + V F K L K+ + Sbjct: 462 SSEGRVHRLALKMVTTD-ESGDVAFVVGDQKSVACLLVEEKPKGAPVFFRKEL-KNQDAV 519 Query: 942 EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 EG V L C+ S + +W I E+ Q+G D G C Sbjct: 520 EGDDVSLRCELSKPGIRVEWRKGGMVIQPSKKYEMKQKGCVQELCIQNLVSEDSGYYTCD 579 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPK 1059 DQ T+ L V+ + L+ +V + A ++++ V W DG ++ Sbjct: 580 AGDQLTTAALAVQAKEVLIVCGLKTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESS 639 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 +GHI L ++N + D G + TA++ V + E+++ +++ V Sbjct: 640 AFTEIGLSQGHIYTLTLKNLAPDDSGTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVV 699 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 + A F + ++ RW K+G ++ + + D +L I +D G Y+C Sbjct: 700 ENQPAEFICQYSR-PVKARWRKNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYAC 758 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 E + A L VE I L + + E+ D W +++ Sbjct: 759 EAEGTCVVASLHVEAKPITIVQGLENVEIFNGGEALFECALSRPESKDCRWLLDGKPVKE 818 Query: 1239 TEKFTLIS--DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKI-VD 1292 + ++S + ++ L++++ + D C T A ++ +L V+V E+ P ++ Sbjct: 819 SPTTEIVSFENGRRHLLLMKELSVKDTCTVTFKAGTASTSAQLSVKVATGSEWQPSTQLE 878 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQP------------NDEWIVNSKIIKKCKHTKPSIDS 1340 + + + +V + QP +D W ++K K+ +P++DS Sbjct: 879 AVEPVELPQTVQLEKVVKPEELGQPSLPPEAAEEGDLHDLWEASAK--KRRMSREPTLDS 936 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN-----ILEIDSS 1395 I + D G+ K + GH VE+ D+ K + E +SS Sbjct: 937 ------ISEQPEEDKGVRKPVDKELQGHETVEVKSVKKDEVIKSKKVDSKLYTSSEEESS 990 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAY 1454 S + +++ + + + + T + + + +T + ++T + + Sbjct: 991 SGGLSLVAYLKKSSTSAVTATNDAETLSTERFFEHFQMAEHRTVQVTKVETTTDQQTPEK 1050 Query: 1455 AV------NEVDISDAS-ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 V E ++S+A+ + +K K K P ++ K+ T EP+ I L C+ G Sbjct: 1051 LVPVEKKSEEEELSEAAVKIQAAFKGYKARKDMRPVFKETFKDQTKEPSGTIHLECVVQG 1110 Query: 1508 VPQPKVTWYRDGKKLKTAK 1526 P KV W +DG+ L K Sbjct: 1111 KPD-KVRWLKDGELLTDGK 1128 Score = 109 bits (263), Expect = 6e-22 Identities = 121/573 (21%), Positives = 229/573 (39%), Gaps = 37/573 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ P F K+ + Q V EG +L C + P+ + WL + + S+ + Sbjct: 320 VKAAPVLFKKELENQEVLEGDKAILSCE-TSHPDCSVRWLKGSTVLTHGDKYSIEQRATA 378 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 H C + K+ +VK G YT ++ ASL + +E +++ L + V Sbjct: 379 HTLC-IHKL-DVK--DSGEYTCDTGDKRSSASLTV--------REHVRILRELCDVTVTT 426 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G+ + ++ + W + ++ S+G H + LK + G Sbjct: 427 GQDALFEVELSHSGVTAGEWWLGDNLLQNNDLNQMSSEGRVHRLA-LKMVTTDESGDVAF 485 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + + +A + VEE + P F + E + L +++ P + Sbjct: 486 VVGDQKSVA----CLLVEE--KPKGAPVFFRKELKNQDAVEGDDVSLRCELSK-PGIRVE 538 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + +I PS+ G EL I N+ SE DSG Y C AG A + + Sbjct: 539 WRKGGMVIQPSKKYEMKQKGCVQELCIQNLVSE-DSGYYTC----DAGDQLTTAALAVQA 593 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREI-IQEGRXX 982 ++V V L K+ + G+ CQ S K W+ + + EI + +G Sbjct: 594 KEVLIVCGL-KTTDVFVGEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQGHIY 652 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS 1042 D G + ++ L+VK+ E + +++D V E A + S Sbjct: 653 TLTLKNLAPDDSGTVMFKAGSLTSTAKLLVKDPTVEVVSEMEDIHVVENQPAEFICQY-S 711 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 W ++G+ ++ + E+ ++ +LYI S D G Y+C A + V Sbjct: 712 RPVKARWRKNGQPLRADGRRVVVEQDWNVARLYISRVSTEDGGTYACEAEGTCVVASLHV 771 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTI--DGK 1159 P I+ L+N ++ G +A FE L++ ++ RW DG ++ S ++ +G+ Sbjct: 772 EAKPITIVQGLENVEIFNGGEALFECALSRPESKDCRWLLDGKPVKESPTTEIVSFENGR 831 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 + L + + + D + + G + +A L+V+ Sbjct: 832 RHLLLMKELSVKDTCTVTFKAGTASTSAQLSVK 864 Score = 88.6 bits (210), Expect = 2e-15 Identities = 59/206 (28%), Positives = 107/206 (51%), Gaps = 13/206 (6%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVI-LSAQVVGNPRPTITWCKNNKPVKA---LPTKSDG 784 T + + PQ++E L + V G + + +V G P+P + W K+ P+++ + + + Sbjct: 1480 TEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERILLQVER 1539 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 D HS+ I++ K+ D G Y+ N+ G A +SA +TV ++E PP F+ RF V Sbjct: 1540 DVHSLEIVEVKR-SDMGEYSAYISNAAGSAYSSARLTVLN-SKEPLVPPRFLERFSNRKV 1597 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEI-----ISP-SETITQNFDGENIELVITNVDSE 898 K+ +I L +V +P P ++W + + I P ++ G L++ +V +E Sbjct: 1598 KQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHRHSLILMDVGTE 1657 Query: 899 IDSGDYKCVASNSAGKSSHGARVTID 924 +G Y C+A+N AG+S A + +D Sbjct: 1658 Y-TGAYTCIATNRAGQSICTAHLEVD 1682 Score = 81.4 bits (192), Expect = 2e-13 Identities = 75/346 (21%), Positives = 130/346 (37%), Gaps = 15/346 (4%) Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTK 1132 +L I D G YSC D +A + V P L++Q V++G+ EL+K Sbjct: 9 ELVIMELRPEDSGSYSCCSDDTISSASLVVNAAPVLFTKELESQTVDEGDDVRLHCELSK 68 Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 + W K + + G + L I+D D +D+G Y+C+ G+ + TA L V+ Sbjct: 69 PAVPLEWKKGELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTAQLIVK 128 Query: 1193 EPSINFTLRLPEFILVP-------------ANTDAYLTVEIPDETLDVTWYKKKSVIEDT 1239 P N L + P A A L E V W V+ + Sbjct: 129 VPFRNTILLIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDKVLSSS 188 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRI 1299 K+ L D L++ K D Y+C +++ L V+ +E I+ + + Sbjct: 189 SKYRLRQDGSTVELVVYKLQGPDAGVYSCDTGSQRTSAVLTVQEIEV--SILKFLESCVV 246 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 G DV P +W + ++ + D + SLT++ V D+G Sbjct: 247 SEGEDVRFECLVSREEAPLVQWKLQDVPLQDNQMNVIESDGRLHSLTLRGVTEADSGTVT 306 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 + N+ A + + + +LE D + ++ P+ Sbjct: 307 FTVGNHTSTASLTVKAAPVLFKKELENQEVLEGDKAILSCETSHPD 352 Score = 63.3 bits (147), Expect = 7e-08 Identities = 59/227 (25%), Positives = 103/227 (45%), Gaps = 34/227 (14%) Query: 498 FEKPTSEEQSMAPIFVEKLRPKHTPDGSTV-QFECQVEGYPRPQITWFRQTAIIKPSQDF 556 FE T ++Q P VE+L H G+ + + + +V+G+P+P++ WF+ ++ S+ Sbjct: 1476 FESVTEDDQ--LPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERI 1533 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXX 616 + + D V +L I EV D G ++ NAAG A S+ L V + E V Sbjct: 1534 LLQVERD-VHSLEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVL-----NSKEPLV--- 1584 Query: 617 XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG--EEI 674 PP F ++ + V +G+ I L ++ P P ++WL + E++ Sbjct: 1585 ----------------PPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDV 1628 Query: 675 --VPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719 + + I S H + +L +V G YT +A NR G++ Sbjct: 1629 LWIKPDTKGYKIASSGHRHSLIL--MDVGTEYTGAYTCIATNRAGQS 1673 Score = 56.0 bits (129), Expect = 1e-05 Identities = 57/228 (25%), Positives = 98/228 (42%), Gaps = 19/228 (8%) Query: 1090 ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQ 1147 I RD VT + P+I+ L + V+ G T KG V WFKDG ++ Sbjct: 1469 ISRDTETFESVTEDDQLPQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLR 1528 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL--PEF 1205 S I L ++ L+I + D GEYS + N+ +A + +N L P F Sbjct: 1529 SSERILLQVERDVHSLEIVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPPRF 1588 Query: 1206 I------LVPANTDAYLTVEIP-DETLDVTWYKKKSVIE------DTEKFTLISDVKKRT 1252 + V T L+V++ T V+W K++S+ + DT+ + + S + + Sbjct: 1589 LERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGYKIASSGHRHS 1648 Query: 1253 LIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYR 1298 LI+ + YTC+ + +S +EV + P + +++ R Sbjct: 1649 LILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDDIPQRRRQQKKKVR 1696 Score = 55.6 bits (128), Expect = 1e-05 Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 1/116 (0%) Query: 485 QKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544 +++L+E K+ K + M P+F E + + T+ EC V+G P ++ W Sbjct: 1060 EEELSEAAVKIQAAFKGYKARKDMRPVFKETFKDQTKEPSGTIHLECVVQGKP-DKVRWL 1118 Query: 545 RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + ++ + + + +D +LVI + +D G +TC N G +S + ++ V Sbjct: 1119 KDGELLTDGKHYHIDIYNDGTCSLVITAITTKDTGVYTCEVTNKFGVSSHSGKVTV 1174 Score = 54.0 bits (124), Expect = 4e-05 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-----IKPSQDFQ 557 S+E + P F+E+ + G+++ +VEG P P ++W ++ ++ IKP Sbjct: 1579 SKEPLVPPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPDTKGY 1638 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + +L++ +V E G +TC+A N AG + T L V+ Sbjct: 1639 KIASSGHRHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVD 1682 Score = 51.2 bits (117), Expect = 3e-04 Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 12/212 (5%) Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 G +L I + +D+G YSC ++ +A L V + FT L E V D L Sbjct: 5 GLHYELVIMELRPEDSGSYSCCSDDTISSASLVVNAAPVLFTKEL-ESQTVDEGDDVRLH 63 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 E+ + + W K + + K+ + + TL+I +D YTC D +ST Sbjct: 64 CELSKPAVPLEWKKGELGLCPCTKYDIKQAGTRATLVIHDVDPEDSGSYTCDTGDCQSTA 123 Query: 1278 KLKVEVV-----------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 +L V+V P + + + ++ + L P + W K Sbjct: 124 QLIVKVPFRNTILLIFSHAAQPVLFKTQLQNLERQAGESASLCCETTKPGASVVWRHGDK 183 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ + D + L + K++ DAG+Y Sbjct: 184 VLSSSSKYRLRQDGSTVELVVYKLQGPDAGVY 215 Score = 49.6 bits (113), Expect = 0.001 Identities = 24/96 (25%), Positives = 45/96 (46%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 A P+F+ Q V + + V P P++ WY++ +++ ++ N D E + Sbjct: 1349 AAAPVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQ 1408 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 +I D G Y+C A N +G +S A + +D+ Sbjct: 1409 QLIITTVLPTDMGVYRCTAENGSGITSTKAELRVDM 1444 Score = 47.6 bits (108), Expect = 0.004 Identities = 23/88 (26%), Positives = 40/88 (45%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 ++G P P V W+K+G+ L + + + + + I E+KRS +Y+ SN AG++ Sbjct: 1510 VKGFPKPRVYWFKDGHPLRSSERILLQVERDVHSLEIVEVKRSDMGEYSAYISNAAGSAY 1569 Query: 1656 VEVTLKVYDKPSKPEGPVIMREISRESV 1683 L V + P + S V Sbjct: 1570 SSARLTVLNSKEPLVPPRFLERFSNRKV 1597 Score = 46.4 bits (105), Expect = 0.009 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 3/92 (3%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-FDGENIELV 891 P+F F++ T + GTI L V P + W ++ E+++ + + ++ LV Sbjct: 1085 PVFKETFKDQTKEPSGTIHLECVVQGKP-DKVRWLKDGELLTDGKHYHIDIYNDGTCSLV 1143 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 IT + ++ D+G Y C +N G SSH +VT+ Sbjct: 1144 ITAITTK-DTGVYTCEVTNKFGVSSHSGKVTV 1174 Score = 45.6 bits (103), Expect = 0.015 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Query: 1288 PKIVDYEREYRIKRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P+IV+ + + G+ +T + + + FP+P W + ++ + ++ SL Sbjct: 1486 PQIVEELHDVHVSPGAPITKMQLKVKGFPKPRVYWFKDGHPLRSSERILLQVERDVHSLE 1545 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 I +V+ +D G Y + N G A +T+L+ P P LE Sbjct: 1546 IVEVKRSDMGEYSAYISNAAGSAYSSARLTVLNSKEPLVPPRFLE 1590 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 7/96 (7%) Query: 509 API-FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 AP+ F ++L + +G V+ C++ P + W + + P + + AT Sbjct: 41 APVLFTKELESQTVDEGDDVRLHCELSK-PAVPLEWKKGELGLCPCTKYDIKQAGTR-AT 98 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 LVI +V PED+G++TC G ST +LIV+ P Sbjct: 99 LVIHDVDPEDSGSYTC----DTGDCQSTAQLIVKVP 130 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1107 PEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGK-KQKLK 1164 P +T LQ+Q V G +F+ + + K VRW+KDG ++ ++H + D + +Q+L Sbjct: 1352 PVFLTELQSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQLI 1411 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 I D G Y C N Sbjct: 1412 ITTVLPTDMGVYRCTAEN 1429 Score = 41.5 bits (93), Expect = 0.25 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 504 EEQSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 E+ AP+F K L+ + +G V C++ P ++ W + +I+PS+ ++M Sbjct: 500 EKPKGAPVFFRKELKNQDAVEGDDVSLRCELSK-PGIRVEWRKGGMVIQPSKKYEMK-QK 557 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 V L I+ + ED+G +TC AG +T L V+A Sbjct: 558 GCVQELCIQNLVSEDSGYYTC----DAGDQLTTAALAVQA 593 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 1582 QKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRS 1638 Q V D + V+ V+ G PPP V WYK+G LE + Y I +E + I + + Sbjct: 1359 QSQDVPDGYPVSFDCVVIGKPPPTVRWYKDGKLLEENDHYMINEDQEGRQQLIITTVLPT 1418 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKV 1662 Y A N +G +S + L+V Sbjct: 1419 DMGVYRCTAENGSGITSTKAELRV 1442 Score = 41.1 bits (92), Expect = 0.33 Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 14/123 (11%) Query: 1008 TMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEI-----IKPK 1059 T+L KE + P F+ + + +VK+ L V++ S T V W ++ + IKP Sbjct: 1575 TVLNSKEPLVPPRFLERFSNRKVKQGTSITLSVKVEGSPTPMVSWLKEESMEDVLWIKPD 1634 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQN 1115 Y GH L + + G Y+CI + + CTA + V ++P R Q Sbjct: 1635 TKGYKIASSGHRHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDDIPQR--RRQQK 1692 Query: 1116 QKV 1118 +KV Sbjct: 1693 KKV 1695 Score = 37.9 bits (84), Expect = 3.0 Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Query: 541 ITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI 599 + WF+ + ++ + +Q Y + V LVI+ + D G + C N G A +L+ Sbjct: 2201 VEWFKDSRLLTDQEKYQTYSELRSGVLVLVIKNLTERDLGHYECEMSNRLGSARCGADLV 2260 Query: 600 VEAPLSDHGSE-MTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 + + ++ G + +T+ I+E T K P+ Sbjct: 2261 LPSAVARTGEQAVTIEVTEQETKIPKKTIIIEETITTVVKNPR 2303 Score = 37.5 bits (83), Expect = 4.0 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G V+FEC V P + W Q ++ +Q + D + +L +R V D+GT T Sbjct: 248 EGEDVRFECLVSREEAPLVQWKLQDVPLQDNQ-MNVIESDGRLHSLTLRGVTEADSGTVT 306 Query: 583 CVAKNAAGFASSTTE 597 N AS T + Sbjct: 307 FTVGNHTSTASLTVK 321 Score = 37.5 bits (83), Expect = 4.0 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G F CQ+ ++ W+ ++ S ++ ++ TL ++ + P+D+GT Sbjct: 610 GEWATFSCQLSARAPGKVQWWLDGTRLESSAFTEIGLSQGHIYTLTLKNLAPDDSGT--- 666 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEM 611 AG +ST +L+V+ P + SEM Sbjct: 667 -VMFKAGSLTSTAKLLVKDPTVEVVSEM 693 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 4/86 (4%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 V ++ H + +F CQ Y RP + W + ++ + D NVA L I Sbjct: 690 VSEMEDIHVVENQPAEFICQ---YSRPVKARWRKNGQPLRADGRRVVVEQDWNVARLYIS 746 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTE 597 V ED GT+ C A+ AS E Sbjct: 747 RVSTEDGGTYACEAEGTCVVASLHVE 772 >UniRef50_Q676A1 Cluster: Cardiac myosin-binding protein C; n=1; Oikopleura dioica|Rep: Cardiac myosin-binding protein C - Oikopleura dioica (Tunicate) Length = 1200 Score = 151 bits (367), Expect = 2e-34 Identities = 117/501 (23%), Positives = 218/501 (43%), Gaps = 37/501 (7%) Query: 1022 KLQDFE-VKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 KL D E V + E + +E W R+G+ I + + E+RG RKL I N + Sbjct: 279 KLPDTECVPNNGKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENAN 338 Query: 1081 VHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWF 1140 + D+G + +E + EV V+E P + ++ ++ +G A F L+ + Sbjct: 339 LMDDGLFEIRAGEEKSSCEVHVLEAPTAVTKGFEDLQLVQGEDAKFTATLSTAHGRFKIL 398 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200 KDG E +++ +T DG +I DAG Y + +K L V+ + F Sbjct: 399 KDGIEFGLNDNQTVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKS 458 Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 R + + V N A + + D + W +E++E +I+D R L++++ + Sbjct: 459 RFSD-VNVNVNEPAEFSCIVSDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGK 517 Query: 1261 DDQCEYTCVL--LDAKSTTKLKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQ 1316 ++ EY ++ D K T + + + I E+E +K G TL + P Sbjct: 518 ANEGEYQFLVDSKDHKQPTGITATLKTYSVTIEKPQGEKEIVVKAGQKFTLDIPISGDPA 577 Query: 1317 PNDEWIVNSKIIKKCKHT--------------KP---SIDSKS----------ASLTIKK 1349 P W + K + C++T KP D K + + I Sbjct: 578 PQMSWFLGEKEL-YCENTPSGEFTNPLDRPFDKPFGKPADPKQRVQIKNWPERSRVHIPT 636 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 V D+G+Y L+L++ G ++ + ++ KP PG P I E+++ + W P G Sbjct: 637 VHKADSGVYTLKLKSEAGTDSIDFKLLVIHKPGAPGIPIISELNNECCRVDWTPPVELGG 696 Query: 1410 STIIYYVVEYQEIDTTEWISVKN-ITKTQTSI-QNLKTNSSYRFRAYAVNEVDISDASET 1467 + Y+VE ++ ++ WI + + +T + + + ++Y+ R AVN+V + + S Sbjct: 697 CEVEGYIVERKKTSSSRWIRLNSQLTTFHNHLARRMVEGTAYQVRVTAVNQVGVGEPSPV 756 Query: 1468 TEYYKVIKETKIQSPTVEKPL 1488 +E + + T + P++ K L Sbjct: 757 SESFTPMAPTS-EIPSIRKGL 776 Score = 101 bits (242), Expect = 2e-19 Identities = 105/482 (21%), Positives = 193/482 (40%), Gaps = 37/482 (7%) Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 G + + I + S + I + ++ S YT++ + AGT S++ L V KP P Sbjct: 612 GKPADPKQRVQIKNWPERSRVHIPTVHKADSGVYTLKLKSEAGTDSIDFKLLVIHKPGAP 671 Query: 1670 EGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 P+I E++ E ++W PP++ GG E+ Y +E+ + ++RWI++ + + Sbjct: 672 GIPIIS-ELNNECCRVDWTPPVELGGCEVEGYIVERKKTSSSRWIRLNSQLTTFHNHLAR 730 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789 ++ E Y RV A N VG E P+ P+ ++S+ + W Sbjct: 731 RMVEGTAYQVRVTAVNQVGVG---EPSPVSESFTPMAPTSEIPSIRKGLTADDSIELKWA 787 Query: 1790 PSEKNGGSPIIDYKVEIK----------------QEGKKWKXXXXXXXXXARI-QKLSIN 1832 E G + Y ++++ + WK ++I L Sbjct: 788 APEDQGALGMKGYLIQLQVLKNPSSENPLMELEDDAWEDWKKTKIAPDSNSQILDGLDTG 847 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEPE 1890 TY FR+ A N G S +T+ + + + P + PR L + P Sbjct: 848 KTYMFRMAAENAAGRS-KWTTFGPVVCAEAMEDPRINLPRPLTRLVKIRCGEKLHFQCPF 906 Query: 1891 SNGGSPITNYI-IEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVG- 1947 P+ + ++ +G + + EH + I R + + G Sbjct: 907 VGRPKPVVTWTKVDSLPEEGVNTLPEGVEEKPLGEHVTVRESVGMAVIHIRNTDRSDTGC 966 Query: 1948 --VSLPT-ESQSVRLEKHATV--PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 + L + ++V + K A V PS P A + +G++ V W +P+ DG + Y Sbjct: 967 YKMRLAVGDKEAVAIIKVAIVEPPSKPRALKIVETIGTS-VQLEWESPKDDGNTEIFAYT 1025 Query: 2003 IAIRDV---TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 + RD W V + + K +I DL + + R+ A+NE+GLSE + + + Sbjct: 1026 VEKRDKRSGADGQWFIVYE-KIRHCKCSIDDLIMGNEFQFRVKAQNEVGLSEGIATKDFA 1084 Query: 2060 KV 2061 K+ Sbjct: 1085 KI 1086 Score = 91.9 bits (218), Expect = 2e-16 Identities = 65/247 (26%), Positives = 112/247 (45%), Gaps = 20/247 (8%) Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 A + I+ + +D G YK+RL A + V I++ PS P I+E +S+ + W+ Sbjct: 952 AVIHIRNTDRSDTGCYKMRLAVGDKEAVAIIKVAIVEPPSKPRALKIVETIGTSVQLEWE 1011 Query: 1403 EPENTGNSTIIYYVVEYQE----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 P++ GN+ I Y VE ++ D +I + I + SI +L + ++FR A NE Sbjct: 1012 SPKDDGNTEIFAYTVEKRDKRSGADGQWFIVYEKIRHCKCSIDDLIMGNEFQFRVKAQNE 1071 Query: 1459 VDISDASETTEYYKVIKE--TKI----------QSPTVEKPLKNITTEPNEDIELTCIFG 1506 V +S+ T ++ K+ KE T + Q P+ PL N ++C Sbjct: 1072 VGLSEGIATKDFAKIEKERLTYVKPEYKSRDVSQPPSFTLPLNNRKLTIGYTGTISCSVR 1131 Query: 1507 GVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 G P+PK+ W+++ ++ K + Y C+A+NDHGEV Sbjct: 1132 GQPKPKIRWFKNKIEIIDNPKYKMSASLGVVQLEIRRPRQADQGTYTCLAYNDHGEVSCD 1191 Query: 1563 CVVGIQQ 1569 V +++ Sbjct: 1192 AQVMVRE 1198 Score = 65.3 bits (152), Expect = 2e-08 Identities = 65/306 (21%), Positives = 123/306 (40%), Gaps = 10/306 (3%) Query: 943 GKTVILECQTSHTVSTKWYHNKKEISGMD-HREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 GK V + + TKW+ N +EI+ + H +I Q GR D G+ + Sbjct: 290 GKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENANLMDDGLFEIRA 349 Query: 1002 KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKN 1061 ++++S + V E + +D ++ + + A +++ +DG N Sbjct: 350 GEEKSSCEVHVLEAPTAVTKGFEDLQLVQGEDAKFTATLSTAHGRFKILKDGIEFGLNDN 409 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 + + G + I+ S D G Y E+ V P +R + VN Sbjct: 410 Q-TVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKSRFSDVNVNVN 468 Query: 1122 NKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 A F ++ + +W +G ++ S +IQ+ DG +KL + + + GEY V Sbjct: 469 EPAEFSCIVSDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGKANEGEYQFLVD 528 Query: 1182 NS--KCTAILTVEEPSINFTLRLPE---FILVPANTDAYLTVEIP-DETLDVTWY--KKK 1233 + K +T + + T+ P+ I+V A L + I D ++W+ +K+ Sbjct: 529 SKDHKQPTGITATLKTYSVTIEKPQGEKEIVVKAGQKFTLDIPISGDPAPQMSWFLGEKE 588 Query: 1234 SVIEDT 1239 E+T Sbjct: 589 LYCENT 594 Score = 53.2 bits (122), Expect = 8e-05 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S + S P F L + G T C V G P+P+I WF+ I + ++M Sbjct: 1100 SRDVSQPPSFTLPLNNRKLTIGYTGTISCSVRGQPKPKIRWFKNKIEIIDNPKYKM-SAS 1158 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 V L IR D GT+TC+A N G S +++V P Sbjct: 1159 LGVVQLEIRRPRQADQGTYTCLAYNDHGEVSCDAQVMVREP 1199 Score = 49.6 bits (113), Expect = 0.001 Identities = 68/312 (21%), Positives = 122/312 (39%), Gaps = 12/312 (3%) Query: 1058 PKK-NKYDFEKRGHIRKLYIRNTSV-HDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115 PKK + D + RG ++K S H +Y +L+ + T +V EI Sbjct: 225 PKKIQEEDLDFRGKLKKETTPKISFKHGLKDYRGMLKRMAATRKVNKRSNAYEIKLP-DT 283 Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAG 1174 + V K FE + +WF++G EI N H ++ G+ +KL I + +L D G Sbjct: 284 ECVPNNGKLVFEAVVANEALGTKWFRNGQEITSQNTHFKIEQRGRTRKLIIENANLMDDG 343 Query: 1175 EYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKS 1234 + G K + + V E T + LV DA T + K Sbjct: 344 LFEIRAGEEKSSCEVHVLEAPTAVTKGFEDLQLVQGE-DAKFTATLSTAHGRFKILKDGI 402 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVD 1292 + T+ D I+K ++ D Y AKS +L V+ V F + D Sbjct: 403 EFGLNDNQTVTRDGAVVNFEIKKISKSDAGFYEIQTNGAKSFGELIVDSKPVAFKSRFSD 462 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 + ++ + +V + + +W N K +++ ++ + D L +K+V Sbjct: 463 VN--VNVNEPAEFSCIV---SDAEVAGKWTFNGKPVEESENIQIIADGTDRKLVLKEVGK 517 Query: 1353 TDAGIYKLRLEN 1364 + G Y+ +++ Sbjct: 518 ANEGEYQFLVDS 529 Score = 45.6 bits (103), Expect = 0.015 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 3/134 (2%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVI 753 +K N EG T E E + + K+ + +PP PL + + G + Sbjct: 1066 VKAQNEVGLSEGIATKDFAKIEKERLTYVKPEYKSRDVSQPPSFTLPLNNRKLTIGYTGT 1125 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSE 811 +S V G P+P I W KN + P + + L+ ++ + D+G YT A N Sbjct: 1126 ISCSVRGQPKPKIRWFKNKIEIIDNPKYKMSASLGVVQLEIRRPRQADQGTYTCLAYNDH 1185 Query: 812 GIAETSAVITVEEP 825 G A + V EP Sbjct: 1186 GEVSCDAQVMVREP 1199 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 1601 PPEVIWYKNG-NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 PP V W K N++ Y I++++ + + K S S YTI+ S+ AG S Sbjct: 145 PPRVQWVKGKWNEITAGDRYQISSEKNSHTLTFSMPKMSDSGIYTIKVSSPAGLDSKTFE 204 Query: 1660 LKVYDKPSKPEGPVIMR 1676 LKV + S G V++R Sbjct: 205 LKVSPEKSASSGIVVVR 221 Score = 40.3 bits (90), Expect = 0.57 Identities = 39/164 (23%), Positives = 66/164 (40%), Gaps = 10/164 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 I++ P F + V+ C +V+ E W F G+ + ENI + + Sbjct: 448 IVDSKPVAFKSRFSDVNVNVNEPAEFSC-IVSDAEVAGKWTFNGKPVEESENIQIIADGT 506 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMI 745 VLK V K EG Y + +++ + I +KT E PQ K ++ Sbjct: 507 DRKL--VLK--EVGKANEGEYQFLVDSKDHKQPTGITATLKTYSVTIEKPQ---GEKEIV 559 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 V+ G+ L + G+P P ++W K + T S T+ + Sbjct: 560 VKAGQKFTLDIPISGDPAPQMSWFLGEKELYCENTPSGEFTNPL 603 Score = 37.5 bits (83), Expect = 4.0 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 11/114 (9%) Query: 815 ETSAVITVEEPTEENAEPPLF---INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN- 870 E + E + + ++PP F +N +++T+ GTI R P P I W++N Sbjct: 1089 ERLTYVKPEYKSRDVSQPPSFTLPLNN-RKLTIGYTGTISCSVR--GQPKPKIRWFKNKI 1145 Query: 871 EII-SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 EII +P ++ + +E+ + D G Y C+A N G+ S A+V + Sbjct: 1146 EIIDNPKYKMSASLGVVQLEI---RRPRQADQGTYTCLAYNDHGEVSCDAQVMV 1196 Score = 37.1 bits (82), Expect = 5.3 Identities = 20/96 (20%), Positives = 45/96 (46%), Gaps = 2/96 (2%) Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 + Q P T+ + +K +G ++ + G P P++ W+KN ++ ++ +Y ++ Sbjct: 1103 VSQPPSFTLPLNN--RKLTIGYTGTISCSVRGQPKPKIRWFKNKIEIIDNPKYKMSASLG 1160 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + I+ +++ YT A N G S + + V Sbjct: 1161 VVQLEIRRPRQADQGTYTCLAYNDHGEVSCDAQVMV 1196 >UniRef50_UPI0000DB8006 Cluster: PREDICTED: similar to sallimus CG1915-PC, isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar to sallimus CG1915-PC, isoform C - Apis mellifera Length = 4011 Score = 150 bits (364), Expect = 4e-34 Identities = 124/434 (28%), Positives = 192/434 (44%), Gaps = 41/434 (9%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 L +FEK EE+ +AP F ++P + EC V G P P++ W+R +KP + Sbjct: 2455 LVIFEK---EEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEELKPEK 2511 Query: 555 DFQMYYDDDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 ++ ++ + A L I E ED + A N G A L++ + Sbjct: 2512 GREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVR-------- 2563 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEE 673 ++L P ++ A + G + L + P P++ W G E Sbjct: 2564 ---------VSKPEVLRS--PKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAE 2612 Query: 674 IVP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKI--- 727 IVP D+ + E+ +Y I V K G Y V N GEA S + +K Sbjct: 2613 IVPSDKRVIKIYENTTELY-----IPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKRED 2667 Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787 KT E + P+ IEPL+ IV +GE VI+ +V P + W + +P+++ P Sbjct: 2668 KTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQE 2727 Query: 788 SITILKPKKVKDE--GVYTLKAENSEGIAETSAVIT-VEEPTEENAE--PPLFINRFQEI 842 + +IL K++K E G YT +AEN G +A I ++ P EE E P F+ R + Sbjct: 2728 NKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPV 2787 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDS 901 V + + L V P P + WY +N+ I + IT D E + L IT V E D+ Sbjct: 2788 RVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPE-DA 2846 Query: 902 GDYKCVASNSAGKS 915 G+Y C A N G++ Sbjct: 2847 GEYTCRAVNPVGEA 2860 Score = 128 bits (310), Expect = 1e-27 Identities = 127/494 (25%), Positives = 205/494 (41%), Gaps = 41/494 (8%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T +++ +AP F++KL+P +T +F C V G P P+ITW+R + S+ + M Sbjct: 2360 TDKDKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTI- 2418 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 + A+L I +V EDAG ++C A N AG A+ST L++ + + Sbjct: 2419 YETTASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMV 2478 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 +LE I T + P+ ++ G + L PE F E +I Sbjct: 2479 EEHKPALLECI-VTGTPMPEVKWY-RGEEELK-------PEKGREITFNPETGEAKLHIL 2529 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEP 740 E D +Y ++ V KF + ++ S P VL+ P++ P Sbjct: 2530 EPTEEDETIY----RVRAVNKFGRAECRANLVISNVVRVSKPEVLR-------SPKITRP 2578 Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV 797 L +++ G+ + LSA P P + W +N P K +T + I + K Sbjct: 2579 LPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTK- 2637 Query: 798 KDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 KD G Y ++ EN G A +S +TV+ E + + P FI Q V E + + R Sbjct: 2638 KDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETR 2697 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 V P S W+ + + + + L+I + E SG Y C A N G Sbjct: 2698 VDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEY-SGTYTCRAENVGGSV 2756 Query: 916 SHGARV---------TIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNK 964 + A + T+++ TFVK L +G++ L C Q T +WYH+ Sbjct: 2757 TCTATINLLDTPWEETVELVSPTFVKRL-SPVRVMDGESANLTCIVQGKPTPRVEWYHDN 2815 Query: 965 KEISGMDHREIIQE 978 K I I+Q+ Sbjct: 2816 KPIKEGKEITIVQD 2829 Score = 120 bits (288), Expect = 6e-25 Identities = 145/570 (25%), Positives = 237/570 (41%), Gaps = 57/570 (10%) Query: 678 ENISVAIESDMHMY-CSVLKITNVKKFQEGTYTV----VAVN---REGEASLPIVLKIKT 729 E I V +E ++ V++ T V+K E V V V R+ + + + I Sbjct: 2302 EEIPVPVEKEVSTQEVQVIEATKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITD 2361 Query: 730 GEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS 788 +K+ P+ I+ L+ +I + + + V GNP P ITW +N + + A + Sbjct: 2362 KDKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYET 2421 Query: 789 ITILKPKKVKDE--GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 L+ KVK+E G+Y+ +A N G+A ++ + + E EE P F + + V+E Sbjct: 2422 TASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPH-FATPIKPLMVEE 2480 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD-SEIDSGDYK 905 L VT P+P + WYR E + P + F+ E E + ++ +E D Y+ Sbjct: 2481 HKPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYR 2540 Query: 906 CVASNSAGKSSHGARVTI-DVEKVTFVKHLQKSYET--------EEGK--TVILECQTSH 954 A N G++ A + I +V +V+ + L+ T E GK T+ + ++ Sbjct: 2541 VRAVNKFGRAECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKP 2600 Query: 955 TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTML 1010 T KWY N EI D R I D G + V+ + +S + Sbjct: 2601 TPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSV 2660 Query: 1011 VVKE--------TIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKN 1061 VK+ P FI LQ V E +V I+E ++S TA W D ++ Sbjct: 2661 TVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLE-STP 2719 Query: 1062 KYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELP---------PE 1108 + + + L I+ G Y+C + +CTA + +++ P P Sbjct: 2720 QVRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPT 2779 Query: 1109 IITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLKIY 1166 + RL +V G A I K V W+ D I+ I + D + L I Sbjct: 2780 FVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAIT 2839 Query: 1167 DCDLDDAGEYSCE----VGNSKCTAILTVE 1192 + +DAGEY+C VG + CT+ L VE Sbjct: 2840 EVFPEDAGEYTCRAVNPVGEAVCTSSLIVE 2869 Score = 116 bits (279), Expect = 7e-24 Identities = 121/495 (24%), Positives = 199/495 (40%), Gaps = 46/495 (9%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P F +K + + C + P P+I W +E+ E + I + Sbjct: 2366 IAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTI----YET 2421 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQG 749 + L+IT VK+ G Y+ A N G A+ + L I E+E P P+K ++V + Sbjct: 2422 TASLEITKVKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEH 2481 Query: 750 ESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDT--HSITILKPKKVKDEGVYT 804 + +L V G P P + W + KP K + +T + IL+P + +DE +Y Sbjct: 2482 KPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTE-EDETIYR 2540 Query: 805 LKAENSEGIAETSA------VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 ++A N G AE A V+ V +P E P + + + L A Sbjct: 2541 VRAVNKFGRAECRANLVISNVVRVSKP--EVLRSPKITRPLPALVAEFGKPLTLSADFES 2598 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P + WYRN I PS+ EL I V + D G Y+ N G++ Sbjct: 2599 KPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKK-DGGKYEVRVENPVGEARSS 2657 Query: 919 ARVTI--------DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEIS 968 VT+ +V+ F++ LQ T EG+ VI+E + T S +W+H+ + + Sbjct: 2658 GSVTVKKREDKTDEVKAPRFIEPLQPQIVT-EGEVVIMETRVDSYPTASFQWFHDTRPLE 2716 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-----TSTMLVV----KETI--- 1016 I+ + G C ++ T+T+ ++ +ET+ Sbjct: 2717 STPQVRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELV 2776 Query: 1017 -PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKL 1074 P F+++L V + + A L + + T V W D + IK K + + L Sbjct: 2777 SPTFVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSL 2836 Query: 1075 YIRNTSVHDEGEYSC 1089 I D GEY+C Sbjct: 2837 AITEVFPEDAGEYTC 2851 Score = 113 bits (272), Expect = 5e-23 Identities = 156/636 (24%), Positives = 250/636 (39%), Gaps = 67/636 (10%) Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 V R E L V K K EK + ++PLK ++ E + + V + W K Sbjct: 2247 VERIEEIVLKPVEKEKFEEKPKEEELKPLKLEKPKKLEEEEIEEEKVTE----MLWKKPE 2302 Query: 773 K-PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK----AENSEGIAETSAVITVEEPTE 827 + PV S + I K +K+ ++ V K E+ + + + + Sbjct: 2303 EIPVPVEKEVSTQEVQVIEATKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITDK 2362 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 + P FI + Q + + + T K V NP P ITWYRN + + SE Sbjct: 2363 DKKIAPRFIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETT 2422 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQ---KSYETEEG 943 L IT V E D+G Y C ASN AG ++ + I + E+ H K EE Sbjct: 2423 ASLEITKVKEE-DAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEH 2481 Query: 944 KTVILECQTSHT--VSTKWYHNKKEISGMDHREII---QEGRXXXXXXXXXXXXD-VGVI 997 K +LEC + T KWY ++E+ REI + G + + + Sbjct: 2482 KPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRV 2541 Query: 998 KCIVK--DQETSTMLVVKETI----------PEFIRKLQDFEVKEKDVAILEVEINSE-T 1044 + + K E LV+ + P+ R L + L + S+ T Sbjct: 2542 RAVNKFGRAECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPT 2601 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCTAEV 1100 +V W R+G I P +K + + +LYI + D G+Y + + + V Sbjct: 2602 PEVKWYRNGAEIVP-SDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSV 2660 Query: 1101 TVVE--------LPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNH 1151 TV + P I LQ Q V +G E + + A +WF D ++ + Sbjct: 2661 TVKKREDKTDEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQ 2720 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAIL---------TVEEPSINF 1198 +++ K L I + + +G Y+C G+ CTA + TVE S F Sbjct: 2721 VRIVTQENKSILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTF 2780 Query: 1199 TLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVK-KRTLIIR 1256 RL + V A LT + + T V WY I++ ++ T++ D + +L I Sbjct: 2781 VKRLSP-VRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAIT 2839 Query: 1257 KCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPP 1288 + +D EYTC + +A T+ L VE E+ P Sbjct: 2840 EVFPEDAGEYTCRAVNPVGEAVCTSSLIVEAYEYVP 2875 Score = 92.7 bits (220), Expect = 1e-16 Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 34/380 (8%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W N + + + +I +ASL I KV+ DAG+Y R N G A +N Sbjct: 2395 PFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPAGVATSTVN 2454 Query: 1375 VTILDKP--------SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426 + I +K + P KP ++E ++ C T + +Y E +E+ + Sbjct: 2455 LVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECI--VTGTPMPEVKWYRGE-EELKPEK 2511 Query: 1427 WISVKNITKT-QTSIQNLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETK---IQ 1480 + +T + + L+ +R AVN+ ++ V++ +K ++ Sbjct: 2512 GREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVRVSKPEVLR 2571 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXX 1536 SP + +PL + E + + L+ F P P+V WYR+G ++ K YEN Sbjct: 2572 SPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELY 2631 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV---------- 1586 Y+ N GE +S V ++++ T +++K + Sbjct: 2632 IPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKT---DEVKAPRFIEPLQPQIVTE 2688 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ ++ ++ P W+ + LE+ + I T+E S++ IKE+K +S YT Sbjct: 2689 GEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEYSGTYTCR 2748 Query: 1647 ASNTAGTSSVEVTLKVYDKP 1666 A N G+ + T+ + D P Sbjct: 2749 AENVGGSVTCTATINLLDTP 2768 Score = 91.1 bits (216), Expect = 3e-16 Identities = 59/191 (30%), Positives = 86/191 (45%), Gaps = 17/191 (8%) Query: 508 MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 ++P FV++L P DG + C V+G P P++ W+ IK ++ + D + V + Sbjct: 2776 VSPTFVKRLSPVRVMDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCS 2835 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA----PLSDHGSEMTVXXXXXXXXXX 623 L I EVFPEDAG +TC A N G A T+ LIVEA P S+ S + V Sbjct: 2836 LAITEVFPEDAGEYTCRAVNPVGEAVCTSSLIVEAYEYVPDSEIASSI-VATSLTTGQSG 2894 Query: 624 XXADIL------------EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG 671 D+L E P K P+ G LE ++ P+P+ W +G Sbjct: 2895 SEEDLLSPKETPLFDTDEESAPEIVKKLPQLIPTKVGELTRLEVKVKGKPKPEGKWYKQG 2954 Query: 672 EEIVPDENISV 682 EIV + + Sbjct: 2955 VEIVSSQEFLI 2965 Score = 85.4 bits (202), Expect = 2e-14 Identities = 74/273 (27%), Positives = 114/273 (41%), Gaps = 26/273 (9%) Query: 468 WVPAQYLMDENNYTQYLQKKLNE--KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGS 525 ++P D Y ++ + E + V ++ ++ AP F+E L+P+ +G Sbjct: 2631 YIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVTEGE 2690 Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 V E +V+ YP WF T ++ + ++ +N + L+I+E+ PE +GT+TC A Sbjct: 2691 VVIMETRVDSYPTASFQWFHDTRPLESTPQVRI-VTQENKSILMIKEIKPEYSGTYTCRA 2749 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 +N G + T + L D E TV E + PTF K+ V Sbjct: 2750 ENVGGSVTCTATI----NLLDTPWEETV----------------ELVSPTFVKRLSPVRV 2789 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 +G L C + P P + W + I E + I D CS L IT V Sbjct: 2790 MDGESANLTCIVQGKPTPRVEWYHDNKPI--KEGKEITIVQDTEGVCS-LAITEVFPEDA 2846 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 G YT AVN GEA L ++ E P I Sbjct: 2847 GEYTCRAVNPVGEAVCTSSLIVEAYEYVPDSEI 2879 Score = 84.2 bits (199), Expect = 4e-14 Identities = 190/857 (22%), Positives = 327/857 (38%), Gaps = 86/857 (10%) Query: 718 EASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--P 774 E L + K K E++P +V ++P+K + + E +++ + V +P + K P Sbjct: 2004 EVKLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPVKKEKPEEEKPEEVKLKP 2063 Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 VK LP + + +KPK+ K E V S ++E VEE E+ AE L Sbjct: 2064 VKRLPKEEEEKE-----VKPKEEKPEEVKLKPIPKS--VSEK-----VEEKPEDEAEKIL 2111 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPS---ITWYRNNEIISPSETITQNFDGENIELV 891 R + K K + VT P+ IT + EI + + Q + + I Sbjct: 2112 PWRRGK----KTKKIVDFREEVTVVPIDQEKVITEIHDEEI----KIVEQKVEAKKI--- 2160 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 V +EI ++K +++ + I+ EKV V+ ++ +E + VI + Sbjct: 2161 ---VQAEIK--EFKEEKPELPWRTTKEVKEIIE-EKVV-VEEIKPETVLKEDE-VIEDVT 2212 Query: 952 TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--QETSTM 1009 S VS W +K +E+++ ++ V+K + K+ +E Sbjct: 2213 ESSEVS--WRKRRKPKKPEKEKEVVELKPVEKHEEFVERIEEI-VLKPVEKEKFEEKPKE 2269 Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAIL----EVEINSETADVVWERDGEIIKPKKNKYDF 1065 +K E +KL++ E++E+ V + EI V ++ ++I+ K + Sbjct: 2270 EELKPLKLEKPKKLEEEEIEEEKVTEMLWKKPEEIPVPVEKEVSTQEVQVIEATKVEKIV 2329 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125 E + K + V D + ++ P I +LQ A Sbjct: 2330 EDVVEVEK---KKVQVEDRRRKHKQRTQVEISITDKDKKIAPRFIQKLQPVIAQPETTAK 2386 Query: 1126 FEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 F + + W+++ E+ S +TI L+I +DAG YSC N Sbjct: 2387 FTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPA 2446 Query: 1185 CTAILTV-------EEPSINFTLRLP-EFILVPANTDAYLTVEIPDETL-DVTWYKKKSV 1235 A TV EE I P + ++V + A L + + +V WY+ + Sbjct: 2447 GVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEE 2506 Query: 1236 I--EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-------EF 1286 + E + T + + L I + TE+D+ Y ++ + + +V Sbjct: 2507 LKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNVVRVSK 2566 Query: 1287 P-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 P PKI + G +TL D+++ P P +W N I I Sbjct: 2567 PEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYEN 2626 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNILEIDSSSIN 1398 + L I +V D G Y++R+EN G A +VT+ DK P +E I Sbjct: 2627 TTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQI- 2685 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS----VKNITKTQTSIQNLKTNSSYRFRAY 1454 + E Y +Q T + V+ +T+ SI +K Y Sbjct: 2686 VTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEYSGTY 2745 Query: 1455 AVNEVDISDASETTEYYKVI----KET-KIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 ++ + T ++ +ET ++ SPT K L + E LTCI G P Sbjct: 2746 TCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCIVQGKP 2805 Query: 1510 QPKVTWYRDGKKLKTAK 1526 P+V WY D K +K K Sbjct: 2806 TPRVEWYHDNKPIKEGK 2822 Score = 83.0 bits (196), Expect = 8e-14 Identities = 78/309 (25%), Positives = 124/309 (40%), Gaps = 35/309 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + E P P++ W+R A I PS D ++ +N L I EV +D G + Sbjct: 2587 GKPLTLSADFESKPTPEVKWYRNGAEIVPS-DKRVIKIYENTTELYIPEVTKKDGGKYEV 2645 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +N G A S+ + V+ D E+ P F + + Q Sbjct: 2646 RVENPVGEARSSGSVTVKKR-EDKTDEVKA--------------------PRFIEPLQPQ 2684 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V EG +++E R+ + P W + + + + + S+L I +K Sbjct: 2685 IVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENK----SILMIKEIKPE 2740 Query: 704 QEGTYTVVAVNREGEASLPIVLKI------KTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 GTYT A N G + + + +T E P ++ L + V GES L+ Sbjct: 2741 YSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCI 2800 Query: 758 VVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIA 814 V G P P + W +NKP+K DT + L +V +D G YT +A N G A Sbjct: 2801 VQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEYTCRAVNPVGEA 2860 Query: 815 ETSAVITVE 823 ++ + VE Sbjct: 2861 VCTSSLIVE 2869 Score = 73.7 bits (173), Expect = 5e-11 Identities = 153/719 (21%), Positives = 274/719 (38%), Gaps = 71/719 (9%) Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 V ++ EA + +IK ++E P++ P ++ ++ + +I VV +P T K + Sbjct: 2151 VEQKVEAKKIVQAEIKEFKEEKPEL--PWRT--TKEVKEIIEEKVVVEEIKPE-TVLKED 2205 Query: 773 KPVKALPTKSDGDTHSITILKPKKV-KDEGVYTLK-AENSEGIAETSAVITVEEPTEENA 830 + ++ + S+ KPKK K++ V LK E E E I ++ +E Sbjct: 2206 EVIEDVTESSEVSWRKRR--KPKKPEKEKEVVELKPVEKHEEFVERIEEIVLKPVEKEKF 2263 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 E + + +++ ++ + V + W + EI P E + + IE Sbjct: 2264 EEKPKEEELKPLKLEKPKKLE-EEEIEEEKVTEMLWKKPEEIPVPVEKEVSTQEVQVIEA 2322 Query: 891 VITN--VDSEIDSGDYKCVASNSAGKSSHGARVTIDV----EKVT--FVKHLQKSYETEE 942 V+ ++ K + K +V I + +K+ F++ LQ E Sbjct: 2323 TKVEKIVEDVVEVEKKKVQVEDRRRKHKQRTQVEISITDKDKKIAPRFIQKLQPVIAQPE 2382 Query: 943 GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 T C + WY N++E+ + + D G+ C Sbjct: 2383 -TTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCR 2441 Query: 1001 VKDQE---TSTM-LVVKET-----IPEFIRKLQDFEVKEKDVAILE-VEINSETADVVWE 1050 + TST+ LV+ E P F ++ V+E A+LE + + +V W Sbjct: 2442 ASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWY 2501 Query: 1051 RDGEIIKPKKNK-YDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVEL 1105 R E +KP+K + F KL+I + DE Y ++ C A + + + Sbjct: 2502 RGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISNV 2561 Query: 1106 ----PPEI-----ITR-LQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQL 1154 PE+ ITR L G T + +K V+W+++G+EI S+ + Sbjct: 2562 VRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVI 2621 Query: 1155 TIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFT-LRLPEFI--- 1206 I +L I + D G+Y V G ++ + +TV++ ++ P FI Sbjct: 2622 KIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPL 2681 Query: 1207 ---LVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 +V + + T W+ +E T + +++ K L+I++ + Sbjct: 2682 QPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENKSILMIKEIKPEY 2741 Query: 1263 QCEYTCVL--LDAKSTTKLKVEVVEFP---------PKIVDYEREYRIKRGSDVTLLVDY 1311 YTC + T + +++ P P V R+ G L Sbjct: 2742 SGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRVMDGESANLTCIV 2801 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS-ASLTIKKVENTDAGIYKLRLENNCGHA 1369 Q P P EW ++K IK+ K D++ SL I +V DAG Y R N G A Sbjct: 2802 QGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEYTCRAVNPVGEA 2860 Score = 73.3 bits (172), Expect = 7e-11 Identities = 70/286 (24%), Positives = 113/286 (39%), Gaps = 25/286 (8%) Query: 1420 QEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 QE+ +E +I T I +K + + A N + A+ T KE + Sbjct: 2406 QELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRASNPAGV--ATSTVNLVIFEKEEE 2463 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXX 1535 +P P+K + E ++ L CI G P P+V WYR ++LK K T+ Sbjct: 2464 GIAPHFATPIKPLMVEEHKPALLECIVTGTPMPEVKWYRGEEELKPEKGREITFNPETGE 2523 Query: 1536 XXXXX---XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV------ 1586 Y+ A N G E C + V+ +S ++ + K+ Sbjct: 2524 AKLHILEPTEEDETIYRVRAVNKFGRAE--CRANLVISNVVRVSKPEVLRSPKITRPLPA 2581 Query: 1587 -----GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 G ++A E P PEV WY+NG ++ + I E T+ + I E+ + Sbjct: 2582 LVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDKRVIKIYENTTELYIPEVTKKDGG 2641 Query: 1642 KYTIEASNTAG--TSSVEVTLKV-YDKPSKPEGPVIMREISRESVT 1684 KY + N G SS VT+K DK + + P + + + VT Sbjct: 2642 KYEVRVENPVGEARSSGSVTVKKREDKTDEVKAPRFIEPLQPQIVT 2687 Score = 71.3 bits (167), Expect = 3e-10 Identities = 100/520 (19%), Positives = 188/520 (36%), Gaps = 38/520 (7%) Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 F +L I P T + + ++TWY+ + + +EK+ + +L I K Sbjct: 2370 FIQKLQPVIAQPETTAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITK 2429 Query: 1258 CTEDDQCEYTCVLLD----AKSTTKLKV---EVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 E+D Y+C + A ST L + E P + ++ L Sbjct: 2430 VKEEDAGMYSCRASNPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPALLECI 2489 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGH 1368 P P +W + +K K + + + ++ + +E T D IY++R N G Sbjct: 2490 VTGTPMPEVKWYRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGR 2549 Query: 1369 ADVEMNVTI-----LDKPSPPGKPNI------LEIDSSSINICWDEPENTGNSTIIYYVV 1417 A+ N+ I + KP P I L + + E+ + +Y Sbjct: 2550 AECRANLVISNVVRVSKPEVLRSPKITRPLPALVAEFGKPLTLSADFESKPTPEVKWYRN 2609 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV-DISDASETTEYYKVIKE 1476 + + + + + T+ I + ++ N V + + T + K Sbjct: 2610 GAEIVPSDKRVIKIYENTTELYIPEVTKKDGGKYEVRVENPVGEARSSGSVTVKKREDKT 2669 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENR 1532 ++++P +PL+ E + + P W+ D + L++ T EN+ Sbjct: 2670 DEVKAPRFIEPLQPQIVTEGEVVIMETRVDSYPTASFQWFHDTRPLESTPQVRIVTQENK 2729 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP----VITISNEDIKQKHKV-- 1586 Y C A N G V + + + P V +S +K+ V Sbjct: 2730 SILMIKEIKPEYSGTYTCRAENVGGSVTCTATINLLDTPWEETVELVSPTFVKRLSPVRV 2789 Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKY 1643 G+ +T +++G P P V WY + ++ KE I E + I E+ + +Y Sbjct: 2790 MDGESANLTCIVQGKPTPRVEWYHDNKPIKEGKEITIVQDTEGVCSLAITEVFPEDAGEY 2849 Query: 1644 TIEASNTAG----TSSVEVTLKVYDKPSKPEGPVIMREIS 1679 T A N G TSS+ V Y S+ ++ ++ Sbjct: 2850 TCRAVNPVGEAVCTSSLIVEAYEYVPDSEIASSIVATSLT 2889 Score = 69.7 bits (163), Expect = 8e-10 Identities = 99/414 (23%), Positives = 165/414 (39%), Gaps = 50/414 (12%) Query: 1380 KPSPPGKPNILEIDSSSIN-ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 K P K EI+ + + W +PE + V QE+ E V+ I + Sbjct: 2276 KLEKPKKLEEEEIEEEKVTEMLWKKPEEI--PVPVEKEVSTQEVQVIEATKVEKIVEDVV 2333 Query: 1439 SIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 ++ K R R + +V+IS K+ KI ++K L+ + +P Sbjct: 2334 EVEKKKVQVEDRRRKHKQRTQVEISITD---------KDKKIAPRFIQK-LQPVIAQPET 2383 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + TC G P P++TWYR+ ++L K YE Y C A Sbjct: 2384 TAKFTCTVFGNPFPEITWYRNEQELHASEKYIMTIYETTASLEITKVKEEDAGMYSCRAS 2443 Query: 1554 NDHGEVETSCVVGIQQKPVITISNE---DIK----QKHKVGDEWLVTAVIEGIPPPEVIW 1606 N G ++ + I +K I+ IK ++HK L+ ++ G P PEV W Sbjct: 2444 NPAGVATSTVNLVIFEKEEEGIAPHFATPIKPLMVEEHKPA---LLECIVTGTPMPEVKW 2500 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK--YTIEASNTAGTSSVEVTLKVYD 1664 Y+ +L+ +K IT +T ++ L+ + + Y + A N G + L + + Sbjct: 2501 YRGEEELKPEKGREITFNPETGEAKLHILEPTEEDETIYRVRAVNKFGRAECRANLVISN 2560 Query: 1665 --KPSKPE---GPVIMREISRESVTIEWKPPL------DDGGLELTKYAIEKHE--PDNN 1711 + SKPE P I R + ++ E+ PL + K+ E P + Sbjct: 2561 VVRVSKPEVLRSPKITRPL--PALVAEFGKPLTLSADFESKPTPEVKWYRNGAEIVPSDK 2618 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 R IK+ + E Y I ++ + + V +NPVG EA S + +K D Sbjct: 2619 RVIKI--YENTTELY-IPEVTKKDGGKYEVRVENPVG--EARSSGSVTVKKRED 2667 Score = 60.9 bits (141), Expect = 4e-07 Identities = 38/108 (35%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 P+F+ T EE AP V+KL P+ P G + E +V+G P+P+ W++Q I S Sbjct: 2906 PLFD--TDEES--APEIVKKL-PQLIPTKVGELTRLEVKVKGKPKPEGKWYKQGVEIVSS 2960 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 Q+F + +D + L I E +P+D G N G +++TT L VE Sbjct: 2961 QEFLIEEFEDGTSVLTIAETYPDDMGEIVFEVHNPLGVSTTTTYLSVE 3008 Score = 53.2 bits (122), Expect = 8e-05 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 1/103 (0%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E+ T P F++++ + +G T FEC G P P + W++ +I + + ++ Sbjct: 3487 ERGTMSATQSVPRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKI 3546 Query: 559 -YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 D++ L I+ ED T+ C A + G ++ +L V Sbjct: 3547 RLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKLHV 3589 Score = 51.2 bits (117), Expect = 3e-04 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 10/119 (8%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSIT 790 P+ I+ + + ++GE+ + GNP P + W KN+K + P D + +I Sbjct: 3498 PRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKIRLLDEEKKTIL 3557 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN--RFQEITVKEK 847 +K +D+ Y KA + G+ T A + V E T + +F++ +F+E V+EK Sbjct: 3558 TIKHATEEDDATYVCKATSEIGLTTTKAKLHVTEITGKK----IFMDEEQFEEQIVEEK 3612 Score = 48.4 bits (110), Expect = 0.002 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 7/136 (5%) Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 H E E + Q P D+ K G+ + + G P P+V+WYKN + N Sbjct: 3483 HSEDERGTMSATQSVPRFIQEITDVYAKE--GETAVFECIYSGNPVPDVVWYKNDKMIIN 3540 Query: 1616 --DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 + + + +EK +++ IK + Y +A++ G ++ + L V + K + Sbjct: 3541 TPNVKIRLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKLHVTEITGK---KI 3597 Query: 1674 IMREISRESVTIEWKP 1689 M E E +E KP Sbjct: 3598 FMDEEQFEEQIVEEKP 3613 Score = 46.0 bits (104), Expect = 0.011 Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 12/131 (9%) Query: 1226 DVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281 DV WYK +I +T K L+ + KK L I+ TE+D Y C +TTK K+ Sbjct: 3528 DVVWYKNDKMIINTPNVKIRLLDEEKKTILTIKHATEEDDATYVCKATSEIGLTTTKAKL 3587 Query: 1282 EVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK--IIKKCKHTKPSID 1339 V E K + + E ++ +V+ + +P +E K +KK K TK + Sbjct: 3588 HVTEITGKKIFMDEEQFEEQ------IVEEKPKKKPEEEKPHKKKKPEMKKAKETKEKVK 3641 Query: 1340 SKSASLTIKKV 1350 + + K++ Sbjct: 3642 GERVKIDKKEL 3652 Score = 44.8 bits (101), Expect = 0.026 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 3/111 (2%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELV 891 P FI ++ KE T + NPVP + WY+N++ II+ + D E ++ Sbjct: 3498 PRFIQEITDVYAKEGETAVFECIYSGNPVPDVVWYKNDKMIINTPNVKIRLLDEEKKTIL 3557 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 +E D Y C A++ G ++ A+ + V ++T K + EE Sbjct: 3558 TIKHATEEDDATYVCKATSEIGLTTTKAK--LHVTEITGKKIFMDEEQFEE 3606 Score = 41.5 bits (93), Expect = 0.25 Identities = 48/236 (20%), Positives = 94/236 (39%), Gaps = 7/236 (2%) Query: 167 KPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQTPTSFNK 226 KP+ +P + ++ K PK EE E+ + + E PE+ P++ + T + Sbjct: 1262 KPEEEKPEEVKLKPVKRLPK--EEEEKEMVTLKPVKKEKPEE-EKPEEVKLKPTKKEKPE 1318 Query: 227 RSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPKFQLKSRI 286 K +K++ + + E V + +LPK + + + Sbjct: 1319 EEKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEV 1378 Query: 287 KYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKTELEQPLF 346 +T P + KP +K + R KE + + P K E+ + E+ Sbjct: 1379 --VTLKPVKKEKPEEEKPEEVKLKPV-KRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKL 1435 Query: 347 SYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKIDEIVDEVTIK 402 + +++E E++ K +E P+E+ PE+ + P K K +E + VT+K Sbjct: 1436 KPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVK-RLPKEEEEKEVVTLK 1490 Score = 41.1 bits (92), Expect = 0.33 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKY 1643 KVG+ + ++G P PE WYK G ++ + +E+ I ++ TSV+ I E + Sbjct: 2929 KVGELTRLEVKVKGKPKPEGKWYKQGVEIVSSQEFLIEEFEDGTSVLTIAETYPDDMGEI 2988 Query: 1644 TIEASNTAGTSSVEVTLKV 1662 E N G S+ L V Sbjct: 2989 VFEVHNPLGVSTTTTYLSV 3007 Score = 38.3 bits (85), Expect = 2.3 Identities = 82/374 (21%), Positives = 150/374 (40%), Gaps = 29/374 (7%) Query: 45 RKLQIEELESSKPQHPEEMTVP--QFXXXXXXXXXXXXXQEPAVVKLPKFQLKSRIKFIR 102 +K +++ LE SKP+ PE+ V F Q KLP+ + IK + Sbjct: 922 KKPELKPLEKSKPEAPEKEKVQLKPFQREKPEEKLTIISQ-----KLPEKTQEKEIKEVE 976 Query: 103 D--WPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXXXXXXDLERVTLEKS--DL 158 + W + KP ++ +++ E K L+ + EK + Sbjct: 977 EISWRRKPKKPSISEESPVEKVAEKIVEEKVIKKEEETIEDFKSIA-LKPIKREKKPEER 1035 Query: 159 FDSQEDESKPDVS-QPPQNIIEEAKSEPKLIEE--SEQPIAKTSEIDNEVPEKINVPDDK 215 D +E KP + + EE K +PK IE+ +E PI + + +V P +K Sbjct: 1036 EDKEEIILKPVKHIKKEEESTEEIKLKPKSIEQKVTEIPIEEKKVEEEQVEVSWRKPREK 1095 Query: 216 ETSQTPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQ-FXXXXXXXXXXXXXXETSL 274 + K T IK++ +E+ +E ++ P+ F Sbjct: 1096 VMKEVQK--EKVEDFTAIKLKPEEIIEEVTLKSEKLEKPETFENGEILEEKTELPWRRGK 1153 Query: 275 VKLPKFQLK-SRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKL 333 KL K ++K +I + +S++ I + ++ KE +++K + + Sbjct: 1154 KKLAKEEVKLEQILKLEKQVSKSVEEQIIFKHKDEK-----PEEKEISEIKLKPVKHIEK 1208 Query: 334 PDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKEDVPEQYTITPRKSSAQKID 393 P EK E E L + + +++E E++ K +E P+E+ PE + P K + + Sbjct: 1209 PKEEKPE-EVKLKPVKRL-PKEEEEKEVVTLKPIKKEKPEEEKPE-LKLKPVKHIEKPEE 1265 Query: 394 EIVDEVTIK--KRL 405 E +EV +K KRL Sbjct: 1266 EKPEEVKLKPVKRL 1279 Score = 37.1 bits (82), Expect = 5.3 Identities = 71/327 (21%), Positives = 126/327 (38%), Gaps = 18/327 (5%) Query: 86 VVKLPKFQLKSRI---KFIRDWPPQEMKPIVTYLGSIKQNGELSRNVKEANXXXXXXXXX 142 V +LPK + + + K I+ P+E KP L +K+ + KE Sbjct: 1573 VKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLPK-EEEEKEVITLKPVKKEK 1631 Query: 143 XXXXDLERVTLEKSDLFDSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKT--SE 200 E V L+ +E+E + +P + +E E K E +P+ + E Sbjct: 1632 PEEEKPEEVKLKPVKRLPKEEEEKEVVTLKP---VKKEKPEEEKPEEVKLKPVKRLPKEE 1688 Query: 201 IDNEVPEKINVPDDKETSQTPTSFN-KRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXX 259 + EV V +K + P K K P + E K++E + E V Sbjct: 1689 EEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEEKKVE---EEEKEVVTLKPIKKE 1745 Query: 260 XXXXXXXXXXXETSLVKLPKFQLKSRI---KYITSWPPESIKPLISYMGSIKQNGILSRN 316 + +LPK + + + K + PE KP + +K+ Sbjct: 1746 KPEEEKPEEVKLKPVKRLPKEEEEKEVITLKPVKKEKPEEEKPEEVKLKPVKRLPKEEEE 1805 Query: 317 IKEAAKVKKQVFVPP-KLPDVEKTELEQPLFSYEDIVESKKDENEIIQEKQTLEELPKED 375 K + K+ V + P K E+ + E+ + +++E E+I K +E P+E+ Sbjct: 1806 KKVEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVKRLHKEEEEKEVITLKPVKKEKPEEE 1865 Query: 376 VPEQYTITPRKSSAQKIDEIVDEVTIK 402 PE+ + P K ++ DE + VT+K Sbjct: 1866 KPEEVKLKPVKRLHKEEDE-KEVVTLK 1891 Score = 37.1 bits (82), Expect = 5.3 Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Query: 720 SLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVK 776 +L V K K E++P +V ++P+K + + E +++ + + +P + K PV+ Sbjct: 1853 TLKPVKKEKPEEEKPEEVKLKPVKRLHKEEDEKEVVTLKPLKKEKPEEEKPEEVKLKPVQ 1912 Query: 777 ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 LP + + KP++VK + V L E E T I E+P EE E Sbjct: 1913 RLPKEEEEKEEKPKEEKPEEVKLKPVKHLPKEEEENEVVTLKPIKKEKPEEEKPE 1967 Score = 36.3 bits (80), Expect = 9.2 Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 3/115 (2%) Query: 720 SLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVK 776 +L + K K E++P +V ++P+K + + E +++ + + +P + K PV+ Sbjct: 1452 TLKPIKKEKPEEEKPEEVKLKPVKRLPKEEEEKEVVTLKPIKKEKPEEEKPEEVKLKPVQ 1511 Query: 777 ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 LP + + KP++VK + V L E E T I E+P EE E Sbjct: 1512 RLPKEEEEKEEKPKEEKPEEVKLKPVKHLPKEEEEKEVVTLKPIKKEKPEEEKPE 1566 Score = 36.3 bits (80), Expect = 9.2 Identities = 52/241 (21%), Positives = 94/241 (39%), Gaps = 13/241 (5%) Query: 160 DSQEDESKPDVSQPPQNIIEEAKSEPKLIEESEQPIAKTSEIDNEVPEKINVPDDKETSQ 219 + +E E KP +P + ++ K PK EE E + I E PE+ P++ + Sbjct: 1917 EEEEKEEKPKEEKPEEVKLKPVKHLPK--EEEENEVVTLKPIKKEKPEE-EKPEEVKLKP 1973 Query: 220 TPTSFNKRSKLTPIKIERKEMEVSTPQHAETVDGPQFXXXXXXXXXXXXXXETSLVKLPK 279 + + + ++ + E T + E V + +LPK Sbjct: 1974 VKRLPKEEEEKEVVTLKPVKKEKPTEEKPEEVKLKPIKKEKPEEEKPEEVKLKPVKRLPK 2033 Query: 280 FQLKSRIKYITSWPPESIKPLISYMGSIKQNGILSRNIKEAAKVKKQVFVPPKLPDVEKT 339 + + + +T P + KP K + + +K K +++ V PK E+ Sbjct: 2034 EEEEKEV--VTLKPVKKEKP-----EEEKPEEVKLKPVKRLPKEEEEKEVKPKEEKPEEV 2086 Query: 340 ELEQ-PLFSYEDIVESKKDENEIIQEKQTLEELPK-EDVPEQYTITPRKSSAQKIDEIVD 397 +L+ P E + E +DE E I + ++ K D E+ T+ P + I EI D Sbjct: 2087 KLKPIPKSVSEKVEEKPEDEAEKILPWRRGKKTKKIVDFREEVTVVP-IDQEKVITEIHD 2145 Query: 398 E 398 E Sbjct: 2146 E 2146 Score = 36.3 bits (80), Expect = 9.2 Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Query: 729 TGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDG 784 T E+ P++++ L +I + GE L +V G P+P W K + + + Sbjct: 2910 TDEESAPEIVKKLPQLIPTKVGELTRLEVKVKGKPKPEGKWYKQGVEIVSSQEFLIEEFE 2969 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEI 842 D S+ + D G + N G++ T+ ++VE T+E +P ++ + +E+ Sbjct: 2970 DGTSVLTIAETYPDDMGEIVFEVHNPLGVSTTTTYLSVEGIVGTKEYRKPS-WVTQMEEM 3028 Query: 843 TVKEKG 848 +G Sbjct: 3029 QEALRG 3034 >UniRef50_Q8NDA2 Cluster: Hemicentin-2; n=28; Euteleostomi|Rep: Hemicentin-2 - Homo sapiens (Human) Length = 1340 Score = 150 bits (364), Expect = 4e-34 Identities = 228/992 (22%), Positives = 393/992 (39%), Gaps = 92/992 (9%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK--SMIVRQGESV 752 L++ V GTY+ VAV+ GEA L + EPP + + + + + G + Sbjct: 369 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM----EPPHIEDSGQPTELSLTPGAPM 424 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--KVKDEGVYTLKAENS 810 L G P+P ITW K+ + + T+ + ++ + +L+ + +V+D G+YT AE+ Sbjct: 425 ELLCDAQGTPQPNITWHKDGQAL----TRLENNSRATRVLRVENVQVRDAGLYTCLAESP 480 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G E S + V+ P N P RF + G + L V P P ITW+R+ Sbjct: 481 AGAIEKSFRVRVQAPP--NIVGPRG-PRF--VVGLAPGQLVLECSVEAEPAPKITWHRDG 535 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I+ + TQ F L + + S DSGDY C A N+AG +S RV ++ V Sbjct: 536 -IVLQEDAHTQ-FPERGRFLQLQAL-STADSGDYSCTARNAAGSTSVAFRV--EIHTVPT 590 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHR-EIIQEGRXXXXXXX 987 ++ + +T +L CQ + W ++ + R EI+ EG Sbjct: 591 IRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQ 647 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETAD 1046 D G C+ + S R+ +D V +A+L E + S Sbjct: 648 PVLAQDAGHYLCLASNSAGSD------------RQGRDLRV----LALLPCEASGSPKPL 691 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVV 1103 VVW +DG+ + + + + L + D ++ C++ +E A V Sbjct: 692 VVWWKDGQKLDFRLQQGAYRLLPS-NALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV 750 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEI-QFSNHIQLTIDGKKQ 1161 +PP I + V T A V W K G+++ + +++ G Sbjct: 751 HVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG--- 807 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 L+I AG Y+C NS A LTV+ + LP + A + L Sbjct: 808 ALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPV--VKPLPSVVRAVAEEEVLLP 865 Query: 1218 VE---IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 E IP T +TW K+ + ++ + R I + +D Y C+ ++ Sbjct: 866 CEASGIPRPT--ITWQKEGLNVATGVSTQVLPGGQLR---IAHASPEDAGNYLCIAKNSA 920 Query: 1275 STTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + K VV+ PP I + + GS L + P+PN W + + + + Sbjct: 921 GSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE- 979 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID 1393 K +I S L +K +E DAG Y EN G A +++TIL P P + Sbjct: 980 GKFTI-QPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLR 1038 Query: 1394 SSSINICWDEPENTGNST-IIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 + W G+ T I + V + + TE +S ++ T + S + Sbjct: 1039 LG--DRLWLRCAARGSPTPRIGWTVNDRPV--TEGVSEQDGGSTLQRAA-VSREDSGTYV 1093 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIELTCIFGGVPQP 1511 +A N V + A + +KE +P ++ + EP I+L C+ G P P Sbjct: 1094 CWAENRVGRTQAVS----FVHVKE----APVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 1145 Query: 1512 KVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 + W +DG L+ + ++ Y+C+A N+ G + ++ +Q Sbjct: 1146 DIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 1205 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 PV + +D+ + GD+ + G P P + W + G L + + T S + Sbjct: 1206 PVFQVEPQDMTVRS--GDDVALRCQATGEPTPTIEWLQAGQPLRASR--RLRTLPDGS-L 1260 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ ++ + Y A N G+++ L V Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292 Score = 105 bits (253), Expect = 1e-20 Identities = 128/565 (22%), Positives = 222/565 (39%), Gaps = 51/565 (9%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PPT + V + ++L C IP P ++W G ++ + S Sbjct: 752 VPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPS----- 806 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I G YT A N G A + L ++ V++PL S++ E Sbjct: 807 -GALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASP-----VVKPLPSVVRAVAEE 860 Query: 752 -VILSAQVVGNPRPTITWCKNNKPV-KALPTK-SDGDTHSITILKPKKVKDEGVYTLKAE 808 V+L + G PRPTITW K V + T+ G I P +D G Y A+ Sbjct: 861 EVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASP---EDAGNYLCIAK 917 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 NS G A + V+ PP+ N +++ E L + +P P+ITW + Sbjct: 918 NSAGSAMGKTRLVVQ-------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK 970 Query: 869 NNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 + + +S +E T G EL++ N++ + D+G Y C A N+ G++ +TI V Sbjct: 971 DGQPVSGAEGKFTIQPSG---ELLVKNLEGQ-DAGTYTCTAENAVGRARRRVHLTILVLP 1026 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 V +S + + + S T W N + ++ + ++ Sbjct: 1027 VFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT----EGVSEQDGGSTLQRA 1082 Query: 988 XXXXXDVGVIKCIVKDQETSTMLV----VKETIPEFIRKLQDFEVKEKDVAI-LEVEINS 1042 D G C +++ T V VKE P + + V+ +I L+ + Sbjct: 1083 AVSREDSGTYVCWAENRVGRTQAVSFVHVKEA-PVLQGEAFSYLVEPVGGSIQLDCVVRG 1141 Query: 1043 E-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-- 1099 + D+ W +DG ++ ++ + L I T D G Y C+ +E A+ Sbjct: 1142 DPVPDIHWIKDGLPLRGSHLRHQLQN----GSLTIHRTERDDAGRYQCLAENEMGVAKKV 1197 Query: 1100 -VTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157 + V++ P Q+ V G+ + T + + W + G ++ S ++ D Sbjct: 1198 VILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPD 1257 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN 1182 G L + + + DAG Y C N Sbjct: 1258 G---SLWLENVETGDAGTYDCVAHN 1279 Score = 98.7 bits (235), Expect = 2e-18 Identities = 102/463 (22%), Positives = 183/463 (39%), Gaps = 41/463 (8%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 ++LL C IP P I W +G N++ + + + + L+I + G Y Sbjct: 861 EVLLPCEASGIPRPTITWQKEGL------NVATGVSTQV-LPGGQLRIAHASPEDAGNYL 913 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 +A N G A L ++ PP + L + +G L + G+P P ITW Sbjct: 914 CIAKNSAGSAMGKTRLVVQV----PPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWD 969 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 K+ +PV K ++K + +D G YT AEN+ G A +T+ Sbjct: 970 KDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI------- 1022 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 P+F + +++ + L +P P I W N+ + +E +++ G ++ Sbjct: 1023 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV--TEGVSEQDGGSTLQ 1080 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE-GKTVIL 948 S DSG Y C A N G++ A + V++ ++ SY E G ++ L Sbjct: 1081 RAAV---SREDSGTYVCWAENRVGRTQ--AVSFVHVKEAPVLQGEAFSYLVEPVGGSIQL 1135 Query: 949 EC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-- 1004 +C + W + + G R +Q G D G +C+ +++ Sbjct: 1136 DCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDAGRYQCLAENEMG 1192 Query: 1005 -ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNK 1062 +++V ++ P F + QD V+ D L + E T + W + G+ ++ + Sbjct: 1193 VAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL 1252 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTVV 1103 L++ N D G Y C+ + S TA +V Sbjct: 1253 RTLPD----GSLWLENVETGDAGTYDCVAHNLLGSATARAFLV 1291 Score = 86.2 bits (204), Expect = 9e-15 Identities = 75/290 (25%), Positives = 122/290 (42%), Gaps = 23/290 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+ P + + G + L C P P I W + E +S E D S Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EGVS---EQDGG---S 1077 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+ V + GTY A NR G + +K + P E ++ G S+ Sbjct: 1078 TLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK---EAPVLQGEAFSYLVEPVGGSIQ 1134 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L V G+P P I W K+ P++ + S+TI + ++ D G Y AEN G+ Sbjct: 1135 LDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTER-DDAGRYQCLAENEMGV 1193 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A+ ++ ++ EP Q++TV+ + L + T P P+I W + + + Sbjct: 1194 AKKVVILVLQSAPVFQVEP-------QDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 1246 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 S + DG L + NV++ D+G Y CVA N G ++ A + + Sbjct: 1247 RASRRLRTLPDGS---LWLENVETG-DAGTYDCVAHNLLGSATARAFLVV 1292 Score = 82.6 bits (195), Expect = 1e-13 Identities = 131/641 (20%), Positives = 229/641 (35%), Gaps = 50/641 (7%) Query: 1035 ILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 +LE + +E A + W RDG +++ + F +RG R L ++ S D G+YSC R+ Sbjct: 516 VLECSVEAEPAPKITWHRDGIVLQEDAHT-QFPERG--RFLQLQALSTADSGDYSCTARN 572 Query: 1094 ESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQ-F 1148 + + V + P I + V+ A + A LV W KD + Sbjct: 573 AAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPR 632 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 S ++ +G L+I DAG Y C NS LR+ L+ Sbjct: 633 SPRFEILPEGS---LRIQPVLAQDAGHYLCLASNS-------AGSDRQGRDLRV--LALL 680 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 P P V W+K ++ + + L++ D ++ C Sbjct: 681 PCEASGS-----PKPL--VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFEC 733 Query: 1269 VLL-DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 V+ + +L V PP I D + ++ + + V L P P W Sbjct: 734 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 793 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 + + + + S S +L I + AG Y N+ G A + +T+ P P Sbjct: 794 LG-ARGSGYRV-SPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLP 851 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 +++ + + E TI + + + ++ +S + + Q I + Sbjct: 852 SVVRAVAEEEVLLPCEASGIPRPTITW---QKEGLNVATGVSTQVLPGGQLRIAHASPED 908 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + + A N S +T +V P +E L +++T L C G Sbjct: 909 AGNYLCIAKNSAG-SAMGKTRLVVQV-------PPVIENGLPDLSTTEGSHAFLPCKARG 960 Query: 1508 VPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 P+P +TW +DG+ + A K T + Y C A N G + Sbjct: 961 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 1020 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 I PV T D + ++GD + G P P + W N + ++ ++ Sbjct: 1021 TILVLPVFTTLPGD--RSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTE----GVSEQD 1074 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 S ++ + R S Y A N G + + V + P Sbjct: 1075 GGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 1115 Score = 78.6 bits (185), Expect = 2e-12 Identities = 50/216 (23%), Positives = 96/216 (44%), Gaps = 7/216 (3%) Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLK--NITTEPNEDIELTCIFGGVPQPKVTWY 1516 V +S+A E ++++ T ++ P +E + ++ P +EL C G PQP +TW+ Sbjct: 385 VAVSEAGEARRHFQL---TVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 441 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 +DG+ L + Y C+A + G +E S V +Q P I Sbjct: 442 KDGQALTRLENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP 501 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELK 1636 + ++ +E P P++ W+++G L+ D E+ ++++ L Sbjct: 502 RGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQF--PERGRFLQLQALS 559 Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + S Y+ A N AG++SV ++++ P+ GP Sbjct: 560 TADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGP 595 Score = 71.3 bits (167), Expect = 3e-10 Identities = 72/292 (24%), Positives = 130/292 (44%), Gaps = 32/292 (10%) Query: 632 IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PPTF + PK + V + GS ++L C + +P P + WL ++ +P E+ +V + Sbjct: 35 VPPTF-ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWL---KDRMPVESSAV---HGVV 87 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L+++ ++ Q GTYT VA N + EA V+ + + + + V +G Sbjct: 88 SRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV--AREHHVLEG 145 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSITILKPKKVKDEGVYT 804 + V L + G P P + W K+ P+ L DG + +LK D G YT Sbjct: 146 QEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS---LVLKGLWASDAGAYT 202 Query: 805 LKAENSEG-IAETSAVITVEEPT-EENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPV 861 A N G A V + PT ++ A+ ++R E+ + +V V +P Sbjct: 203 CVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL-------VTMVCPVRGSPP 255 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 ++W ++ + S+ + G + + + D+G + CVA++ AG Sbjct: 256 IHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQL---ADAGIFTCVAASPAG 304 Score = 70.5 bits (165), Expect = 5e-10 Identities = 52/195 (26%), Positives = 80/195 (41%), Gaps = 7/195 (3%) Query: 1482 PTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXX 1538 PT E P + ++ + LTC GVP P VTW +D ++++ Sbjct: 37 PTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLS 96 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVI 1596 Y C+A N E VV + P I S + ++H V G E + Sbjct: 97 RLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSG--VAREHHVLEGQEVRLDCEA 154 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 +G PPP+V W K+G+ L D ++ + +K L S + YT A N AG + Sbjct: 155 DGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDAR 214 Query: 1657 EVTLKVYDKPSKPEG 1671 T+ V P+ +G Sbjct: 215 LHTVNVLVPPTIKQG 229 Score = 66.1 bits (154), Expect = 1e-08 Identities = 129/627 (20%), Positives = 225/627 (35%), Gaps = 55/627 (8%) Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-I 850 ++ +V D+G+Y+ K N G A + +TV+ P P F N E + G+ + Sbjct: 3 IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP-------PTFENPKTETVSQVAGSPL 55 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 L V+ P P++TW ++ + S G ++L +G Y CVA N Sbjct: 56 VLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQ---PAQAGTYTCVAEN 112 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEIS 968 + ++ V + V + + + EG+ V L+C+ W + + Sbjct: 113 TQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL- 171 Query: 969 GMD---HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKL 1023 G D H +G D G C+ + E + + V +P I++ Sbjct: 172 GQDMGPHLRFYLDG--GSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQG 229 Query: 1024 QD----FEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 D + ++ + + S V W +DG + P + GH L I Sbjct: 230 ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSGH--TLRISK 286 Query: 1079 TSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-- 1136 + D G ++C+ + A+ P +R ++ A + + A Sbjct: 287 VQLADAGIFTCVAASPAGVADRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPC 346 Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILT 1190 R KDG + S ++ + L++ D+G YSC E G ++ LT Sbjct: 347 LSCRGMKDGEPL-LSQSLE-----QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT 400 Query: 1191 V-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 V E P I + + E L P L ++TW+K + E + Sbjct: 401 VMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN----NSRA 456 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG---SDV 1305 R L + D YTC+ + V V+ PP IV R R G + Sbjct: 457 TRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVG-PRGPRFVVGLAPGQL 515 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 L +A P P W + ++++ HT+ + L ++ + D+G Y N Sbjct: 516 VLECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGRFLQLQALSTADSGDYSCTARNA 573 Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEI 1392 G V V I P+ P + + Sbjct: 574 AGSTSVAFRVEIHTVPTIRSGPPAVNV 600 Score = 63.3 bits (147), Expect = 7e-08 Identities = 62/284 (21%), Positives = 112/284 (39%), Gaps = 24/284 (8%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S +P + G+ + L C P+P+I W G+ + EN S A VL+ Sbjct: 410 SGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR--------VLR 461 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL--KSMIVRQGESVIL 754 + NV+ G YT +A + G ++++ PP ++ P + ++ ++L Sbjct: 462 VENVQVRDAGLYTCLAESPAGAIEKSFRVRVQA----PPNIVGPRGPRFVVGLAPGQLVL 517 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V P P ITW ++ ++ + L+ D G Y+ A N+ G Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGST 577 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 + + + + PP + V T L + P P ++W ++ + Sbjct: 578 SVAFRVEIHTVPTIRSGPPA-------VNVSVNQTALLPCQADGVPAPLVSWRKDRVPLD 630 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P + ++ I V ++ D+G Y C+ASNSAG G Sbjct: 631 PRSPRFEILPEGSLR--IQPVLAQ-DAGHYLCLASNSAGSDRQG 671 Score = 62.9 bits (146), Expect = 9e-08 Identities = 59/227 (25%), Positives = 95/227 (41%), Gaps = 19/227 (8%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ--GESV 752 L+I + +G Y+ N GEA L ++ PP P K+ V Q G + Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV----PPTFENP-KTETVSQVAGSPL 55 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAEN 809 +L+ V G P PT+TW K+ PV++ S G ++ L+P + G YT AEN Sbjct: 56 VLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQA---GTYTCVAEN 112 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 ++ A V+ V + +E V E ++L P P + W ++ Sbjct: 113 TQAEARKDFVVAVLVAPRIRSS-----GVAREHHVLEGQEVRLDCEADGQPPPDVAWLKD 167 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + F + LV+ + + D+G Y CVA N AG+ + Sbjct: 168 GSPLGQDMGPHLRFYLDGGSLVLKGLWAS-DAGAYTCVAHNPAGEDA 213 Score = 61.3 bits (142), Expect = 3e-07 Identities = 47/190 (24%), Positives = 75/190 (39%), Gaps = 10/190 (5%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKL--KTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556 L C G P+P V W++DG+KL + + Y ++C+ N+ Sbjct: 680 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEV 739 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-EN 1615 GE V + P I D ++T GIP P V W K G +L Sbjct: 740 GEAHRLYQVTVHVPPTIADDQTDFTVTMMA--PVVLTCHSTGIPAPTVSWSKAGAQLGAR 797 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 Y ++ + + I + H+ +YT A N+AG + V L V P P ++ Sbjct: 798 GSGYRVSP---SGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVV 854 Query: 1676 REISRESVTI 1685 R ++ E V + Sbjct: 855 RAVAEEEVLL 864 Score = 57.6 bits (133), Expect = 4e-06 Identities = 45/176 (25%), Positives = 78/176 (44%), Gaps = 7/176 (3%) Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 + +V EG ++ L+C P PD+AWL G + D + D L + + Sbjct: 138 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD----GGSLVLKGL 193 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 G YT VA N GE + + + Q + +++ R GE V + V G Sbjct: 194 WASDAGAYTCVAHNPAGEDARLHTVNVLV-PPTIKQGADGSGTLVSRPGELVTMVCPVRG 252 Query: 761 NPRPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 +P ++W K+ P+ + T G H++ I K ++ D G++T A + G+A+ Sbjct: 253 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISK-VQLADAGIFTCVAASPAGVAD 307 Score = 54.4 bits (125), Expect = 3e-05 Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V C+ G PRP ITW ++ + Q+ L I PEDAG + C+AK Sbjct: 862 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAK 917 Query: 587 NAAGFASSTTELIVEAP 603 N+AG A T L+V+ P Sbjct: 918 NSAGSAMGKTRLVVQVP 934 Score = 50.8 bits (116), Expect = 4e-04 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 1/74 (1%) Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576 R H +G V+ +C+ +G P P + W + + + + + D +LV++ ++ Sbjct: 138 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDG-GSLVLKGLWAS 196 Query: 577 DAGTFTCVAKNAAG 590 DAG +TCVA N AG Sbjct: 197 DAGAYTCVAHNPAG 210 Score = 50.0 bits (114), Expect = 7e-04 Identities = 54/228 (23%), Positives = 91/228 (39%), Gaps = 11/228 (4%) Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 L+I + + D G YSC+V N A+ LTV+ P F E + A + LT Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPP-TFENPKTETVSQVAGSPLVLTC 59 Query: 1219 EIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 ++ VTW K + +E + ++S + L + + YTCV + ++ Sbjct: 60 DVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVAENTQAEA 117 Query: 1278 KLK-VEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + V V P+I RE+ + G +V L + P P+ W+ + + + Sbjct: 118 RKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGP 177 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 SL +K + +DAG Y N G V +L P+ Sbjct: 178 HLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 225 Score = 48.0 bits (109), Expect = 0.003 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ L T +GS C+ G P P ITW + +P + + L+ Sbjct: 935 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG---QPVSGAEGKFTIQPSGELL 991 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ++ + +DAGT+TC A+NA G A L + Sbjct: 992 VKNLEGQDAGTYTCTAENAVGRARRRVHLTI 1022 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F + + G V CQ G P P I W + ++ S+ + D +L Sbjct: 1205 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPD----GSL 1260 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + V DAGT+ CVA N G A++ L+V Sbjct: 1261 WLENVETGDAGTYDCVAHNLLGSATARAFLVV 1292 Score = 45.6 bits (103), Expect = 0.015 Identities = 31/127 (24%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y C+A ++ GE + + + P I S + + G + +G P P + W+ Sbjct: 382 YSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWH 441 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 K+G L E N T V+R++ ++ + YT A + AG ++V P+ Sbjct: 442 KDGQALTR-LENN---SRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPN 497 Query: 1668 --KPEGP 1672 P GP Sbjct: 498 IVGPRGP 504 Score = 44.4 bits (100), Expect = 0.035 Identities = 42/171 (24%), Positives = 65/171 (38%), Gaps = 9/171 (5%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIA 1552 +++ L C G P P V W +DG L Y + Y C+A Sbjct: 146 QEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVA 205 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV--IEGIPPPEVIWYKNG 1610 N GE V + P I + E LVT V + G PP V W K+G Sbjct: 206 HNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGE-LVTMVCPVRGSPPIHVSWLKDG 264 Query: 1611 NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 L + + T +RI +++ + + +T A++ AG + TL+ Sbjct: 265 LPLPLSQRTLLHGSGHT--LRISKVQLADAGIFTCVAASPAGVADRNFTLQ 313 Score = 44.4 bits (100), Expect = 0.035 Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 16/149 (10%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P G ++Q +C V G P P I W + P + + + N +L I +DAG + Sbjct: 1128 PVGGSIQLDCVVRGDPVPDIHWIKDGL---PLRGSHLRHQLQN-GSLTIHRTERDDAGRY 1183 Query: 582 TCVAKNAAGFASSTTELIVE-APLSD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 C+A+N G A L+++ AP+ +MTV D+ T Sbjct: 1184 QCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGD---------DVALRCQATGEPT 1234 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWL 668 P +++ G + RL +P+ + WL Sbjct: 1235 PTIEWLQAGQPLRASRRLRTLPDGSL-WL 1262 Score = 42.7 bits (96), Expect = 0.11 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 3/64 (4%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 EC VE P P+ITW R +++ Q + L ++ + D+G ++C A+NAA Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQEDAHTQF---PERGRFLQLQALSTADSGDYSCTARNAA 574 Query: 590 GFAS 593 G S Sbjct: 575 GSTS 578 Score = 41.9 bits (94), Expect = 0.19 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 10/85 (11%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR--EVFPEDA 578 TP G+ ++ C +G P+P ITW + + ++++ AT V+R V DA Sbjct: 419 TP-GAPMELLCDAQGTPQPNITWHKDGQALTR-------LENNSRATRVLRVENVQVRDA 470 Query: 579 GTFTCVAKNAAGFASSTTELIVEAP 603 G +TC+A++ AG + + V+AP Sbjct: 471 GLYTCLAESPAGAIEKSFRVRVQAP 495 Score = 41.1 bits (92), Expect = 0.33 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 7/95 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +P+ V G D+ L C+ P P I WL G+ + + + Sbjct: 1206 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS------ 1259 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 L + NV+ GTY VA N G A+ L ++ Sbjct: 1260 -LWLENVETGDAGTYDCVAHNLLGSATARAFLVVR 1293 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 5/80 (6%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKP-SQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 T CQ +G P P ++W + + P S F++ + +L I+ V +DAG + C+ Sbjct: 605 TALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPE----GSLRIQPVLAQDAGHYLCL 660 Query: 585 AKNAAGFASSTTELIVEAPL 604 A N+AG +L V A L Sbjct: 661 ASNSAGSDRQGRDLRVLALL 680 Score = 39.9 bits (89), Expect = 0.75 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS + C V G P P +TW + P + ++ L + + P AGT+TC Sbjct: 52 GSPLVLTCDVSGVPAPTVTWLKDR---MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 108 Query: 584 VAKN 587 VA+N Sbjct: 109 VAEN 112 Score = 39.1 bits (87), Expect = 1.3 Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V C V G P ++W + + SQ ++ TL I +V DAG FTC Sbjct: 241 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGH---TLRISKVQLADAGIFTC 297 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMT 612 VA + AG A L S S MT Sbjct: 298 VAASPAGVADRNFTLQCPLSWSRWSSRMT 326 >UniRef50_Q4SM88 Cluster: Chromosome 3 SCAF14553, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 3 SCAF14553, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2007 Score = 149 bits (362), Expect = 6e-34 Identities = 207/1032 (20%), Positives = 407/1032 (39%), Gaps = 76/1032 (7%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C V+ + ++ W G EI P EN+++ + M L I + G+YT Sbjct: 848 VVLLCH-VSAEDAEVTWYKDGCEIHPSENVTLQADGTMRR----LIIRSADTSDAGSYTC 902 Query: 711 VAVNREGEASLPI-VLKIKTGEKEPP-QVIEPLKSMIVRQ--GESVILSAQVVGNPRPTI 766 A N E S+ I + + EPP ++EP +++ + E + L + + + Sbjct: 903 WAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCE-LSRSSGKV 961 Query: 767 TWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W K+ +PV+ P S+G ++IL V D G Y +++ + +TV+ Sbjct: 962 RWYKDGQPVEESPNLQLISEGPYRRLSIL-TGTVNDGGEYVCESDGDSVFFQ----LTVK 1016 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 +P P E+T ++L +++ P + W+R+ + ++ Sbjct: 1017 DPPVRIISPS---ESELELTHVAPERLELSCEISKVEAP-VRWFRDGLEVKEGPSLRLEA 1072 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEG 943 DG L+I V + D+G+Y C + + + VT K++ +++ + ++ G Sbjct: 1073 DGAQRRLIIP-VTTVDDTGEYACDTEDDS--VAFMVTVTEPPVKLSRPQNMPEKLDSHAG 1129 Query: 944 KTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 + ++LE + S KW+ N E+ + + +G D G C V Sbjct: 1130 EPIVLETEVSRPNAVVKWWLNGSEMVESGNVTMTTDGVIHRLTIHSPSPEDSGKYSCDVI 1189 Query: 1003 DQETSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 D + + V E + +RK + + D +LE E++ W ++ ++ Sbjct: 1190 DDKMDFHVTVTEPPVKILRKSEMETELRFLVSDDIVLECELSRANVGAKWYKNNSSVEGD 1249 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 + +Y E+ G L I N + D G+Y +D++ + +VTV E P + R + V Sbjct: 1250 E-RYCEEEEGAFCSLVILNAGLEDSGKYFLDAKDDNISFDVTVEEPPVTFLNREDDVVVT 1308 Query: 1120 --KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 + T ++K A+VRW K + + Q ++G K+ I DAGEY Sbjct: 1309 GYEAESVTLTTYVSKESAIVRWLKAWTAAE-GERFQARMEGHKRTFTIDPLKRSDAGEYI 1367 Query: 1178 CEVGNSKCTAILTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 C++ + L V+ P + F L ++ + V PD+ + + W I Sbjct: 1368 CDINTDQIHFSLLVKVPRVVEFLTELHNTTVLEGEDATFKCVVSPDD-VHLVWLMDNEPI 1426 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE 1296 +++ + TL+I+KC D + T S LKV+ E Sbjct: 1427 ALGDRYQATQNGLCHTLVIKKCQMLDCSKITAEAEGQISKAILKVQ--EAQVMFTKKTDA 1484 Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 + + TL + + +W+ +I+ + + + LTI + +D G Sbjct: 1485 VMAEEFGEATLETEI-SIETGEVQWMRQGVVIQPGPRHTLAQNGCTRRLTIHNLTISDRG 1543 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y R E V++NV +P + I + + + T + Sbjct: 1544 TY--RCETLHDRTQVKLNV----------EPRKICIRKALTD------QETYERETASFE 1585 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 VE D E I K+ + + + Q + +++ R + ++ + + D + ++ Sbjct: 1586 VELSHTD-VEGIWQKDGIRVKPNNQ-WRVSTNGRVHSLTLSNLTLEDTGSVVFSAEGVRT 1643 Query: 1477 TK----IQSP-TVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATY 1529 T ++P ++ K L +I E + L C F +V W+++G +L+ K Y Sbjct: 1644 TARLTVRETPVSILKTLSDIRVEEDFPATLECEFSR-QIIEVRWFKNGAELRPGKNCRIY 1702 Query: 1530 E--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKV 1586 + Y C D GE+ TSC + + + K I ED+ + Sbjct: 1703 STGRKRFCQIMQCSRADSGTYTC----DTGEMNTSCTLEVYEHKLEIMQDLEDLYIQEDQ 1758 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 ++ +E + WYK+G+K+ I ++ + + +K + + Sbjct: 1759 NAVFMCEVSLEEVAGE---WYKDGHKIRPSSTIKIRSEGTKHFLLMCNVKAEDAGEIRFT 1815 Query: 1647 ASNTAGTSSVEV 1658 A + + +EV Sbjct: 1816 ARDVESIAYLEV 1827 Score = 140 bits (338), Expect = 5e-31 Identities = 169/735 (22%), Positives = 282/735 (38%), Gaps = 42/735 (5%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 DI+LEC L + W + DE E + +CS++ I N G Y Sbjct: 1223 DIVLECEL-SRANVGAKWYKNNSSVEGDERYC---EEEEGAFCSLV-ILNAGLEDSGKYF 1277 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG---ESVILSAQVVGNPRPTI 766 + A ++ S + ++ EPP + +V G ESV L+ V + Sbjct: 1278 LDA--KDDNISFDVTVE------EPPVTFLNREDDVVVTGYEAESVTLTTYV-SKESAIV 1328 Query: 767 TWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W K + + +G + TI P K D G Y N++ I S ++ V Sbjct: 1329 RWLKAWTAAEGERFQARMEGHKRTFTI-DPLKRSDAGEYICDI-NTDQI-HFSLLVKVPR 1385 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 E F+ TV E V+ + V + W +NE I+ + + Sbjct: 1386 VVE-------FLTELHNTTVLEGEDATFKCVVSPDDV-HLVWLMDNEPIALGDRYQATQN 1437 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 G L T V + D + + + G+ S A + + +V F K E G+ Sbjct: 1438 G----LCHTLVIKKCQMLDCSKITAEAEGQISK-AILKVQEAQVMFTKKTDAVMAEEFGE 1492 Query: 945 TVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 LE + S T +W I + Q G D G +C Sbjct: 1493 AT-LETEISIETGEVQWMRQGVVIQPGPRHTLAQNGCTRRLTIHNLTISDRGTYRCETLH 1551 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 T L V+ + L D E E++ A EVE++ + +W++DG +KP N++ Sbjct: 1552 DRTQVKLNVEPRKICIRKALTDQETYERETASFEVELSHTDVEGIWQKDGIRVKPN-NQW 1610 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 G + L + N ++ D G TA +TV E P I+ L + +V + Sbjct: 1611 RVSTNGRVHSLTLSNLTLEDTGSVVFSAEGVRTTARLTVRETPVSILKTLSDIRVEEDFP 1670 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 AT E E ++ VRWFK+G+E++ + ++ G+K+ +I C D+G Y+C+ G Sbjct: 1671 ATLECEFSRQIIEVRWFKNGAELRPGKNCRIYSTGRKRFCQIMQCSRADSGTYTCDTGEM 1730 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 + L V E + L E + + + +A E+ E + WYK I + Sbjct: 1731 NTSCTLEVYEHKLEIMQDL-EDLYIQEDQNAVFMCEVSLEEVAGEWYKDGHKIRPSSTIK 1789 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 + S+ K L++ +D E D +S L+VE E P IV R+ R Sbjct: 1790 IRSEGTKHFLLMCNVKAEDAGEIRFTARDVESIAYLEVE--ELPVSIVKPLRD-RTALEK 1846 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 +L + + W + K + + D S L I++V D G Y + + Sbjct: 1847 HRVILECTVSSARCCATWYKDGKEVVPSDRVEILDDGCSLKLVIQEVAVEDEGTYSVEVG 1906 Query: 1364 NNCGHADVEMNVTIL 1378 + A + + L Sbjct: 1907 EHTSKAKLMVEAQAL 1921 Score = 132 bits (319), Expect = 1e-28 Identities = 159/705 (22%), Positives = 293/705 (41%), Gaps = 53/705 (7%) Query: 705 EGTYT--VVAVN---REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 EG Y V +N R G P V+ + G P++ LKS V +GE S Q+ Sbjct: 616 EGNYRFRVCCINKYGRSGHVEFPKVVHLVPG----PKIQNCLKSCEVAEGEDAHFSIQL- 670 Query: 760 GNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 + TW N+ +P + HS+ I + +D+ T A G+ + Sbjct: 671 -STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIAN---GVRD- 725 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 SA + V P E P + + + + I L V+ +P ++W+++ + + + Sbjct: 726 SAPLHVR-PVEVKFSPLSDTDGNKRVETGD--AIVLYCEVS-HPFAQVSWFKDGKELLMT 781 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + + +G+ +VI + D+ +G Y C S + + V + V + Sbjct: 782 DDLNIQSEGKMRRVVIQSADAS-HAGVYTCETSGDIIR--YNVEVAGPPVEFCPVPEEEL 838 Query: 937 SYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + E V+L C S WY + EI ++ + +G D G Sbjct: 839 HKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 898 Query: 996 VIKCIVKDQETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAI---LEVEINSET 1044 C + + ++ P I + +D V E+ V+ L+ E++ + Sbjct: 899 SYTCWAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCELSRSS 958 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W +DG+ ++ N G R+L I +V+D GEY C +S ++TV + Sbjct: 959 GKVRWYKDGQPVEESPN-LQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKD 1017 Query: 1105 LPPEIITRLQNQ-KVNKGNKATFEI--ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P II+ +++ ++ E+ E++K +A VRWF+DG E++ ++L DG ++ Sbjct: 1018 PPVRIISPSESELELTHVAPERLELSCEISKVEAPVRWFRDGLEVKEGPSLRLEADGAQR 1077 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFT--LRLPEFILVPANTDAYLTVE 1219 +L I +DD GEY+C+ + ++TV EP + + +PE + A L E Sbjct: 1078 RLIIPVTTVDDTGEYACDTEDDSVAFMVTVTEPPVKLSRPQNMPEKLDSHAGEPIVLETE 1137 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + V W+ S + ++ T+ +D L I + +D +Y+C ++D K Sbjct: 1138 VSRPNAVVKWWLNGSEMVESGNVTMTTDGVIHRLTIHSPSPEDSGKYSCDVIDDK--MDF 1195 Query: 1280 KVEVVEFPPKIV---DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 V V E P KI+ + E E R D+ L + +W N+ ++ + Sbjct: 1196 HVTVTEPPVKILRKSEMETELRFLVSDDIVLECELSR-ANVGAKWYKNNSSVEGDERYCE 1254 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + SL I D+G Y L +++ ++ +VT+ + P Sbjct: 1255 EEEGAFCSLVILNAGLEDSGKYFLDAKDD----NISFDVTVEEPP 1295 Score = 111 bits (268), Expect = 2e-22 Identities = 124/562 (22%), Positives = 226/562 (40%), Gaps = 37/562 (6%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+KK A +E + LE ++I ++ W+ +G I P ++A L Sbjct: 1478 FTKKTDAVMAEEFGEATLETE-ISIETGEVQWMRQGVVIQPGPRHTLAQNGCTRR----L 1532 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 I N+ GTY ++ + L + E + + L + E+ Sbjct: 1533 TIHNLTISDRGTYRCETLHDRTQVKLNV-------EPRKICIRKALTDQETYERETASFE 1585 Query: 756 AQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ I W K+ KP ++G HS+T L ++D G AE Sbjct: 1586 VELSHTDVEGI-WQKDGIRVKPNNQWRVSTNGRVHSLT-LSNLTLEDTGSVVFSAEG--- 1640 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 T+A +TV E P + +I V+E L +R + + W++N Sbjct: 1641 -VRTTARLTVRET------PVSILKTLSDIRVEEDFPATLECEFSRQII-EVRWFKNGAE 1692 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + P + G I S DSG Y C G+ + + + K+ ++ Sbjct: 1693 LRPGKNCRIYSTGRKRFCQIMQC-SRADSGTYTC----DTGEMNTSCTLEVYEHKLEIMQ 1747 Query: 933 HLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 L+ Y E+ V + C+ S V+ +WY + +I +I EG Sbjct: 1748 DLEDLYIQEDQNAVFM-CEVSLEEVAGEWYKDGHKIRPSSTIKIRSEGTKHFLLMCNVKA 1806 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER 1051 D G I+ +D E+ L V+E ++ L+D EK ILE ++S W + Sbjct: 1807 EDAGEIRFTARDVESIAYLEVEELPVSIVKPLRDRTALEKHRVILECTVSSARCCATWYK 1866 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIIT 1111 DG+ + P ++ + G KL I+ +V DEG YS + + + A++ V ++ Sbjct: 1867 DGKEVVPS-DRVEILDDGCSLKLVIQEVAVEDEGTYSVEVGEHTSKAKLMVEAQALVVVK 1925 Query: 1112 RLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 L++ +V + + A+F+ +++ + W +G +Q + L G KL++ Sbjct: 1926 HLEDLEVTEPDAASFQCQVSVAINKPPVWTLNGENLQPGPWVHLENHGTTYKLRLKSTST 1985 Query: 1171 DDAGEYSCEVGNSKCTAILTVE 1192 D +G +G ++ +A LTV+ Sbjct: 1986 DMSGVVKFTLGKARSSASLTVK 2007 Score = 105 bits (251), Expect = 2e-20 Identities = 202/1033 (19%), Positives = 398/1033 (38%), Gaps = 105/1033 (10%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-------PTK 781 + + +P +I+PL S+ V +GE S ++ G P P + W K+ K + + ++ Sbjct: 146 SSDDKPRFLIKPL-SLRVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISE 204 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA----------- 830 DG + I + + + D+GVYT +A N G A AV+ VE E A Sbjct: 205 QDGGWFQLRIYRTR-MPDKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTS 263 Query: 831 -------------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 EPP+ +++ ++ V E K VT P P I W ++ + Sbjct: 264 RLLPKHRSHKAALEPPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGR 323 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 D E + E D+G Y C ASN+ G + +++ F + L K Sbjct: 324 RHLIFEDREGYYTLKVLYCKEKDTGLYVCAASNALGNTLSAVHLSVKGSAGKFRRPL-KD 382 Query: 938 YETEEGKTVILECQT-SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 E E +LEC +V WY + + + Q+G D GV Sbjct: 383 VEVRERDVAVLECDVPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTIRDVAADDDGV 442 Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 C + D S + + T ++ EV E + A+ VE+ ++ ++ W +DG + Sbjct: 443 YLCEIPDGAKS---IAELT----VKGRSKLEVMEGENAMFCVEVENDEEEIHWFKDG-LQ 494 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDES-------------CTAEV 1100 + ++ + G L N + D G + + R S C AE Sbjct: 495 LHEMHQVILKSFGKTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEA 554 Query: 1101 TV-VELP-PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158 T+ V+ P ++ ++ F +E+ + + W K + + + ++T DG Sbjct: 555 TMDVDRPNSALLAWAPAPNSPTSTRSIFVVEMQEVGS-QEWLKCFTS-ETATSAEVTGDG 612 Query: 1159 K--KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 + + C ++ G S V K + V P I L+ E V DA+ Sbjct: 613 VQCEGNYRFRVCCINKYGR-SGHVEFPK--VVHLVPGPKIQNCLKSCE---VAEGEDAHF 666 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAKS 1275 ++++ T+ TW+ + ++ +F++ K +L+I + +D+ E T + + Sbjct: 667 SIQL-STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRD 725 Query: 1276 TTKLKVEVVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + L V VE F P + D + R++ G + L + + P W + K + Sbjct: 726 SAPLHVRPVEVKFSP-LSDTDGNKRVETGDAIVLYCEV-SHPFAQVSWFKDGKELLMTDD 783 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM---NVTILDKPSPPGKPNIL 1390 + K + I+ + + AG+Y + +VE+ V P + + Sbjct: 784 LNIQSEGKMRRVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSM 843 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTSIQNLKTNSSY 1449 E+D + +C E ++ + +Y + EI +E ++++ + T + I++ T+ + Sbjct: 844 ELD-PVVLLCHVSAE---DAEVTWY-KDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 898 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE--PNEDIELTCIFGG 1507 + +A N + + S V + +P ++ E +EDI L C Sbjct: 899 SYTCWAGN--NSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIHLQCELSR 956 Query: 1508 VPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 KV WY+DG+ ++ + + + +D V V Sbjct: 957 -SSGKVRWYKDGQPVEESPNLQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTV 1015 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 +I+ S +++ H + ++ I + P V W+++G +++ + Sbjct: 1016 KDPPVRIISPSESELELTHVAPERLELSCEISKVEAP-VRWFRDGLEVKEGPSLRLEADG 1074 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT---LKVYDKPSKPE-------GPVIM 1675 + I + +Y + + + V VT +K+ + PE P+++ Sbjct: 1075 AQRRLIIPVTTVDDTGEYACDTEDDSVAFMVTVTEPPVKLSRPQNMPEKLDSHAGEPIVL 1134 Query: 1676 R-EISRESVTIEW 1687 E+SR + ++W Sbjct: 1135 ETEVSRPNAVVKW 1147 Score = 102 bits (244), Expect = 1e-19 Identities = 132/624 (21%), Positives = 247/624 (39%), Gaps = 45/624 (7%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KL 1163 PP +++ + V +G A F +T K + W KDG ++ + D + L Sbjct: 278 PPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGRRHLIFEDREGYYTL 337 Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 K+ C D G Y C +GN+ L+V+ + F L + + V A L + Sbjct: 338 KVLYCKEKDTGLYVCAASNALGNTLSAVHLSVKGSAGKFRRPLKD-VEVRERDVAVLECD 396 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTK 1278 +PDE++ WY + + K+ + +R L IR DD Y C + D AKS + Sbjct: 397 VPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTIRDVAADDDGVYLCEIPDGAKSIAE 456 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 L V+ + + G + V+ + + W + + + Sbjct: 457 LTVKG----------RSKLEVMEGENAMFCVEVEN-DEEEIHWFKDGLQLHEMHQVILKS 505 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS-SSI 1397 K+ L V + D+G+ + + +++ + P P + +++D +S Sbjct: 506 FGKTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEAT-MDVDRPNSA 564 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAY 1454 + W N+ ST +VVE QE+ + EW+ + T + + ++ +YRFR Sbjct: 565 LLAWAPAPNSPTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVC 624 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED----IELTCIFGGVPQ 1510 +N+ S E+ KV+ + P ++ LK+ ED I+L+ G Sbjct: 625 CINKYG---RSGHVEFPKVVH--LVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG--- 676 Query: 1511 PKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQ 1568 TW+ + +L+ + + E R K + F +G V S + ++ Sbjct: 677 ---TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANG-VRDSAPLHVR 732 Query: 1569 QKPV--ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 V +S+ D ++ + GD ++ + P +V W+K+G +L + NI ++ K Sbjct: 733 PVEVKFSPLSDTDGNKRVETGDAIVLYCEVSH-PFAQVSWFKDGKELLMTDDLNIQSEGK 791 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + I+ SH+ YT E S +VEV + PE + + + V + Sbjct: 792 MRRVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLL 851 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDN 1710 +D + K E H +N Sbjct: 852 CHVSAEDAEVTWYKDGCEIHPSEN 875 Score = 67.7 bits (158), Expect = 3e-09 Identities = 84/363 (23%), Positives = 132/363 (36%), Gaps = 17/363 (4%) Query: 462 LTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK 519 LT+E + LM+E N Y+ E+ + L + P F+ K Sbjct: 102 LTQEVRQPEVKELMEEPGNGYSALQNGACGEE-NGLSLNGDANDTSSDDKPRFLIKPLSL 160 Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPE 576 G F C++ G P P++ W + + S F + D L I Sbjct: 161 RVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISEQDGGWFQLRIYRTRMP 220 Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI-PPT 635 D G +TC A N G A + L+VEA S M+ + PP Sbjct: 221 DKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTSRLLPKHRSHKAALEPPV 280 Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 K K V EG C + P+P+I W K + + + I D Y + L Sbjct: 281 DVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVW--KKDGVPLEAGRRHLIFEDREGYYT-L 337 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 K+ K+ G Y A N G + L +K + PLK + VR+ + +L Sbjct: 338 KVLYCKEKDTGLYVCAASNALGNTLSAVHLSVK---GSAGKFRRPLKDVEVRERDVAVLE 394 Query: 756 AQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AENSEG 812 V P + ++ + P + G +TI + D+GVY + + ++ Sbjct: 395 CDVPDESVPAAWYLEDQRLMPGTKYGMEQKGTRRRLTI-RDVAADDDGVYLCEIPDGAKS 453 Query: 813 IAE 815 IAE Sbjct: 454 IAE 456 Score = 46.0 bits (104), Expect = 0.011 Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP + RP GS C ++G PRP + W R+ I + + ++ L Sbjct: 7 APRVLGYPRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRY-VLSEEGKAYLL 65 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I V +DAG + C AKN+ G + L VE Sbjct: 66 AIAGVTAQDAGQYICKAKNSIGETYAAASLKVE 98 Score = 41.5 bits (93), Expect = 0.25 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 8/155 (5%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 + G + + +I+G P P+VIW + ++ + Y ++ + K ++ I + + +Y Sbjct: 20 RCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEGKAYLLAIAGVTAQDAGQYI 79 Query: 1645 IEASNTAGTSSVEVTLKV-----YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 +A N+ G + +LKV + +PE +M E ++ ++ GL L Sbjct: 80 CKAKNSIGETYAAASLKVEGEALTQEVRQPEVKELMEEPGNGYSALQNGACGEENGLSLN 139 Query: 1700 KYAIEKHEPDNNRW-IKVAD--VDRDVETYCIQKL 1731 A + D R+ IK VDR + Y KL Sbjct: 140 GDANDTSSDDKPRFLIKPLSLRVDRGEDAYFSCKL 174 Score = 39.5 bits (88), Expect = 0.99 Identities = 35/124 (28%), Positives = 50/124 (40%), Gaps = 7/124 (5%) Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 DI G P P+ GSD L C + P PD+ W K +IV ++ E Sbjct: 2 DIFGGAPRVLGY-PRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEG 60 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMI 745 ++ L I V G Y A N GE LK++ GE +V +P +K ++ Sbjct: 61 KAYL----LAIAGVTAQDAGQYICKAKNSIGETYAAASLKVE-GEALTQEVRQPEVKELM 115 Query: 746 VRQG 749 G Sbjct: 116 EEPG 119 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 3/72 (4%) Query: 859 NPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 +P P + W R N +I+S + +G+ L I V ++ D+G Y C A NS G++ Sbjct: 34 DPRPDVIWERKNVQIVSGGRYVLSE-EGKAYLLAIAGVTAQ-DAGQYICKAKNSIGETYA 91 Query: 918 GARVTIDVEKVT 929 A + ++ E +T Sbjct: 92 AASLKVEGEALT 103 Score = 37.5 bits (83), Expect = 4.0 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 6/103 (5%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P+V+ + ++ R G L + G+PRP + W + N + + +G + + I Sbjct: 8 PRVLGYPRPVLARCGSDATLRCLIDGDPRPDVIWERKNVQIVSGGRYVLSEEGKAYLLAI 67 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP--TEENAEP 832 +D G Y KA+NS G +A + VE T+E +P Sbjct: 68 -AGVTAQDAGQYICKAKNSIGETYAAASLKVEGEALTQEVRQP 109 Score = 36.3 bits (80), Expect = 9.2 Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E + + V+ LR + + V EC V R TW++ + PS ++ DD Sbjct: 1826 EVEELPVSIVKPLRDRTALEKHRVILECTVSS-ARCCATWYKDGKEVVPSDRVEIL-DDG 1883 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 LVI+EV ED GT++ G +S +L+VEA Sbjct: 1884 CSLKLVIQEVAVEDEGTYSV----EVGEHTSKAKLMVEA 1918 >UniRef50_UPI0000F34A69 Cluster: UPI0000F34A69 related cluster; n=2; Bos taurus|Rep: UPI0000F34A69 UniRef100 entry - Bos Taurus Length = 4164 Score = 148 bits (359), Expect = 1e-33 Identities = 242/1155 (20%), Positives = 432/1155 (37%), Gaps = 112/1155 (9%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS + C V G P P +TW + ++ S + L + + P+ AGT+TC Sbjct: 3003 GSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVV---SRGGRLQLSHLQPDQAGTYTC 3059 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VA+NA A + + +V + V +LEG Sbjct: 3060 VAENAQ--AEAHKDFVV---------AVLVAPRIQSSGTTQEHSVLEG------------ 3096 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 D+ L+C + P P + WL G + DE++ + ++ S L + +++ Sbjct: 3097 -----QDVQLDCEVDGQPPPYVVWLKDGSPL--DESVGPYLW--FYLNGSSLVLKDLRAS 3147 Query: 704 QEGTYTVVAVNREGE-ASLPI--VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 G YT VA N GE A L VL T E+ P E +++ R G+ V ++ V G Sbjct: 3148 DSGAYTCVARNAAGEDAKLYTVNVLVPPTIEQGP----EGAGTLVHRLGDLVSMACPVRG 3203 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 +P ++W K+ P LP HS ++ D G +T A + G+A ++ Sbjct: 3204 SPPIHVSWLKDGLP---LPLSHRTHLHSSGRTLRVQLADSGTFTCVAASPAGVANRHFIL 3260 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 V P EP F N ++ V + L +P+P ++W ++ E + P Sbjct: 3261 QVLVPPV--LEPAEFQN---DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLPQS--L 3313 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 ++ G +E +G Y CVA + AG++ ++T+ + Sbjct: 3314 EHGPGLLLEAAEAG-----HAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLL 3368 Query: 941 EEGKTVILECQT--SHTVSTKWYHNKKEIS----GMDHREIIQ-EGRXXXXXXXXX--XX 991 G + L C + T + W+ + + +S G R +++ EG Sbjct: 3369 TPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQGARRVLRVEGVQVSDAGLYTCLAH 3428 Query: 992 XDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWE 1050 G ++ + + + V+ P F+ L ++ +LE + ++ A ++ W Sbjct: 3429 SPAGEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQL------VLECSVEADPAPEIEWH 3482 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPP 1107 R+G +++ + F + G R L ++ S D G+YSC + + + + V PP Sbjct: 3483 REGVLLQADAHT-QFPEEG--RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPP 3539 Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQ-FSNHIQLTIDGKKQKLKIY 1166 + N VN+ + + LV W KDG + S L +G ++ L+I Sbjct: 3540 TV-----NASVNQTTLLPCQADGVP-QPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQ 3593 Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD 1222 +DAG Y C G+ + L V EP P + + A T A L E Sbjct: 3594 PVLAEDAGHYLCLASNPAGSDRQGRDLQVFEPPA--IAPGPSNLTLTAYTPASLPCEASG 3651 Query: 1223 ETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLK 1280 V W+K ++ + + L++ + + D + CV+ + KL Sbjct: 3652 SPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLY 3711 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSID 1339 V PP I D + ++ + V L P P W +++ + + Sbjct: 3712 WVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRV--- 3768 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 S S +L I + G Y N G A + +T+ P P+++ + + Sbjct: 3769 SPSGALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVL 3828 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 E +I + + + Q I ++ + + A N Sbjct: 3829 LPCEASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQN-- 3886 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 A +++ + P ++ L +++ L C G P+PKVTW +DG Sbjct: 3887 ---SAGSAVRKTRLVVQV---PPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDG 3940 Query: 1520 KKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577 + + AK T + Y C A N G + I PV T Sbjct: 3941 QPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILALPVFTTLP 4000 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR 1637 D + ++GD+ + G P P++ W N N+L E ++ ++ S ++ + R Sbjct: 4001 GD--RSLRLGDKLWLHCAARGSPTPQIGWTVN-NRLVTATE-GVSEQDGGSTLQRVAVTR 4056 Query: 1638 SHSSKYTIEASNTAG 1652 S Y A N G Sbjct: 4057 EDSGTYVCWAENRVG 4071 Score = 147 bits (356), Expect = 3e-33 Identities = 229/1067 (21%), Positives = 417/1067 (39%), Gaps = 94/1067 (8%) Query: 649 SDILLECRLVAIPEPDIAWLFKGEE-IVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 S + L C IP P I W F+GEE + P EN + + + +LK+T ++ G Sbjct: 2245 SPLSLFCEATGIPPPGIRW-FRGEEPVSPGENTYLLAGKKISGW--MLKLTRAQEQDRGL 2301 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y+ +A N GEA +++ P+ +R S G+P+P +T Sbjct: 2302 YSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPSSLRASG----SGPSTGHPQPKVT 2357 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV-EEPT 826 W K+ +P+ + ++ + + G Y A N+ G ++V PT Sbjct: 2358 WFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHFQLSVLVVPT 2417 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 + +E+TV I L+ P P+ITW ++ I Q G Sbjct: 2418 ILGVTED---SMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALNNI-QLLPGT 2473 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV-----EKVTFVKHLQKSYETE 941 + L I N E D+G Y CV +N G++ V + + + F + K +T+ Sbjct: 2474 H-GLQILNAQKE-DAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKEVKTK 2531 Query: 942 EGKTVILECQT--SHTVSTKWYHN-----KKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994 T+ LEC++ + WY + +K ++ I+ EGR D Sbjct: 2532 VNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGR--LLQIQPTQVSDS 2589 Query: 995 GVIKCIV------KDQETSTMLVVKETI---PEFIRKLQDF-EVKEKDVAILEVEINS-E 1043 G C+ DQ+ + ++ ET E + ++ E+ E + A L + N+ Sbjct: 2590 GRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVP 2649 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEV 1100 A++ W R G+ +P + R L I D G YSC + E Sbjct: 2650 AAELTWYR-GD--RPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYE 2706 Query: 1101 TVVELPPEIITR----LQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLT 1155 +V PP I+ ++ VN + + + A + W ++G S +Q+ Sbjct: 2707 LLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVL 2766 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSINFTLRLPEFILVPA 1210 +G+ L++ ++ DA Y C G+++ L V+ EP +N PE I Sbjct: 2767 ENGR--ILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLN-----PEQITATL 2819 Query: 1211 NTDAYLTVEI-PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 N+ L ++ + +VTWYK + E+ L+ TL + + D Y C Sbjct: 2820 NSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLLPGT--HTLQLTRVQLLDSGMYICE 2877 Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 L+A V++ P ++ + G L + AFP+P W + + + Sbjct: 2878 ALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPL 2937 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PPGK 1386 + + + + L I+ + +D G+Y R+ N G A ++T+ P+ P Sbjct: 2938 VLPERIQALLGGQ--RLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPPTFENPET 2995 Query: 1387 PNILEIDSSSINICWDEPENTG-NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 + + S + + D TG + + ++ + ++++ V + + + +L+ Sbjct: 2996 EMVSRVAGSPLVLSCDV---TGVPAPAVTWLKDRMPVESSMARGVVS-RGGRLQLSHLQP 3051 Query: 1446 NSSYRFRAYAVNEVDISDASETTEY-YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + + + A N + A ++ V+ +IQS + ++ E +D++L C Sbjct: 3052 DQAGTYTCVAEN----AQAEAHKDFVVAVLVAPRIQSSGTTQ--EHSVLE-GQDVQLDCE 3104 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P P V W +DG L + Y N Y C+A N GE Sbjct: 3105 VDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGEDA 3164 Query: 1561 TSCVVGIQQKPVITISNEDI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 V + P I E H++GD + + G PP V W K+G L Sbjct: 3165 KLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRT 3224 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 ++ + +T +++ + S +T A++ AG ++ L+V P Sbjct: 3225 HLHSSGRTLRVQLAD-----SGTFTCVAASPAGVANRHFILQVLVPP 3266 Score = 141 bits (342), Expect = 2e-31 Identities = 233/1076 (21%), Positives = 401/1076 (37%), Gaps = 100/1076 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P S+ V G +L C A PEP +AW G+ +V E I + Sbjct: 2896 PGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQR---- 2951 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGES 751 L+I + + +G Y+ N GEA L ++ PP P M+ R G Sbjct: 2952 --LEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQV----PPTFENPETEMVSRVAGSP 3005 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAE 808 ++LS V G P P +TW K+ PV++ + S G ++ L+P + G YT AE Sbjct: 3006 LVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGGRLQLSHLQPDQA---GTYTCVAE 3062 Query: 809 NSEGIAETSAVITV-EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N++ A V+ V P +++ QE +V E ++L V P P + W Sbjct: 3063 NAQAEAHKDFVVAVLVAPRIQSS------GTTQEHSVLEGQDVQLDCEVDGQPPPYVVWL 3116 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 ++ + S F LV+ ++ + DSG Y CVA N+AG+ + T++V Sbjct: 3117 KDGSPLDESVGPYLWFYLNGSSLVLKDLRAS-DSGAYTCVARNAAGEDA--KLYTVNVLV 3173 Query: 928 VTFVKHLQKSYET---EEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 ++ + T G V + C + S + W + + + GR Sbjct: 3174 PPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRTHLHSSGR-- 3231 Query: 983 XXXXXXXXXXDVGVIKCIVKDQE--TSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILE 1037 D G C+ + +++ +P + + D V + L Sbjct: 3232 ---TLRVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQNDVAVVRGSLVFLP 3288 Query: 1038 VEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 E S V W +DGE + P+ + H L + G YSC+ E+ Sbjct: 3289 CEARGSPLPFVSWVKDGEPLLPQSLE-------HGPGLLLEAAEAGHAGTYSCVAVSEAG 3341 Query: 1097 TA----EVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDGSEIQFS 1149 A ++TV++ PP I Q +++ E+ +G + W KDG + + Sbjct: 3342 EARRHFQLTVMD-PPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWP 3400 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEF 1205 Q G ++ L++ + DAG Y+C G + + + V+ P P F Sbjct: 3401 EDGQ----GARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRVQAPPNVIGSHGPRF 3456 Query: 1206 I--LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 + L P +VE D ++ W+ ++ V+ + T + + R L ++ + D Sbjct: 3457 VVGLAPGQLVLECSVE-ADPAPEIEWH-REGVLLQADAHTQFPE-EGRFLQLQALSTADS 3513 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA--FPQPNDEW 1321 +Y+C +A +T L V+ R + + T L+ QA PQP W Sbjct: 3514 GDYSCTAHNAAGSTSLAFH--------VEVHRPPTVNASVNQTTLLPCQADGVPQPLVSW 3565 Query: 1322 IVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 + + + + + L I+ V DAG Y N G ++ + + Sbjct: 3566 LKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVFEP 3625 Query: 1381 PS-PPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEID-TTEWISVKNITKTQ 1437 P+ PG N+ + ++ E +G+ ++ + + Q++D + + + + Sbjct: 3626 PAIAPGPSNLTLTAYTPASL---PCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNA 3682 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 ++ S F N V E + Y V T P + + T Sbjct: 3683 LLLEEPSPQDSALFECVVSNGV-----GEARKLYWV---TVHVPPAIADDQTDFTATIMA 3734 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFND 1555 + LTC GVP P V+W + G +L Y Y C A N Sbjct: 3735 PVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPSGALEIGQALPIHTGRYTCAARNA 3794 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G V+ +Q PV+ + K +E L+ GIP P + W K G + Sbjct: 3795 AGMAHKHVVLTVQASPVVKPLPSVVWAVAK--EEVLLPCEASGIPRPSIAWQKEGLSVPA 3852 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 T +RI + + Y A N+AG++ + L V P+ G Sbjct: 3853 ANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTG 3908 Score = 141 bits (341), Expect = 2e-31 Identities = 212/1070 (19%), Positives = 393/1070 (36%), Gaps = 94/1070 (8%) Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 S + L C + A P P++ W G + E I + H L++T V+ G Y Sbjct: 2821 SSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFLL--PGTH----TLQLTRVQLLDSGMY 2874 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 A+N G + L + P P ++V G+ +LS + P PT+ W Sbjct: 2875 ICEALNAAGRDHKLVQLSVLA----PGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAW 2930 Query: 769 CKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 K+ +P+ LP + + ++ +V D+G+Y+ + N+ G A + +TV+ P Sbjct: 2931 QKDGQPL-VLPERIQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVP-- 2987 Query: 828 ENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 P F N E+ + G+ + L VT P P++TW ++ + S G Sbjct: 2988 -----PTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRGG 3042 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 ++L D +G Y CVA N+ ++ V + V + + EG+ V Sbjct: 3043 RLQLSHLQPDQ---AGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDV 3099 Query: 947 ILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 L+C+ W + + + D G C+ ++ Sbjct: 3100 QLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNA 3159 Query: 1005 --ETSTMLVVKETIPEFIRKLQD----FEVKEKDVAILEVEIN-SETADVVWERDGEIIK 1057 E + + V +P I + + + D+ + + S V W +DG + Sbjct: 3160 AGEDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDG-LPL 3218 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEII-TRL 1113 P ++ G ++ + D G ++C+ + A + V +PP + Sbjct: 3219 PLSHRTHLHSSGRTLRVQLA-----DSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEF 3273 Query: 1114 QNQ-KVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 QN V +G+ E +G L V W KDG + + +++ L + + Sbjct: 3274 QNDVAVVRGSLVFLPCE-ARGSPLPFVSWVKDGEPL-----LPQSLE-HGPGLLLEAAEA 3326 Query: 1171 DDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TL 1225 AG YSC E G ++ LTV +P PE +L+ T L + T Sbjct: 3327 GHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTP 3386 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 ++TW+K + E +R L + D YTC+ + + V Sbjct: 3387 NITWHKDGRALSWPED----GQGARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRV 3442 Query: 1285 EFPPKIV-DYEREYRIKRG-SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 + PP ++ + + + + L +A P P EW +++ HT+ + Sbjct: 3443 QAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHREGVLLQADAHTQ--FPEEG 3500 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L ++ + D+G Y N G + +V + P+ N +++ C Sbjct: 3501 RFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVN-----QTTLLPCQA 3555 Query: 1403 EPENTGNSTIIYYVVEYQEID--TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 + ++ ++ + +D +T W+ + + IQ + + + A N Sbjct: 3556 DGVP---QPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAG 3612 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + + + P + N+T L C G P+P V W++DG+ Sbjct: 3613 SDRQGRDLQVF--------EPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQ 3664 Query: 1521 KL--KTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 KL + + Y ++C+ N GE V + P I Sbjct: 3665 KLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPAIADD 3724 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKEL 1635 D + ++T G+P P V W K G +L Y ++ + + I + Sbjct: 3725 QTDFTA--TIMAPVVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVS---PSGALEIGQA 3779 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 H+ +YT A N AG + V L V P P ++ +++E V + Sbjct: 3780 LPIHTGRYTCAARNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLL 3829 Score = 138 bits (335), Expect = 1e-30 Identities = 214/993 (21%), Positives = 388/993 (39%), Gaps = 91/993 (9%) Query: 734 PPQVIE---PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK--SDGDTHS 788 PP++I PL ++ + L + G P P I W + +PV G S Sbjct: 2226 PPELIGDLGPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKIS 2285 Query: 789 ITILKPKKV--KDEGVYTLKAENSEGIA--ETSAVITVEEPTEENAEPPLFINRFQEITV 844 +LK + +D G+Y+ A N G A + S + P + PP+ + ++ Sbjct: 2286 GWMLKLTRAQEQDRGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPS-----SL 2340 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 + G+ T +P P +TW+++ + ++ + + DG + ++ N+ S +G Y Sbjct: 2341 RASGS----GPSTGHPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSS---AGHY 2393 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV------ILECQTSHTVST 958 CVA+N+ G+ + ++++ V T + + S + E T+ I E + T + Sbjct: 2394 ACVAANAIGEKTKHFQLSVLVVP-TILGVTEDSMDEEVTVTINNPISLICETRAFPTPTI 2452 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI 1016 W + +++ +++ D G C+V ++ E V+ I Sbjct: 2453 TWMKDGVPFEALNNIQLLP--GTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLI 2510 Query: 1017 PEFIRKLQDF------EVKEKDVAILEVEINS---ETADVVWERDGEII--KPKKNKYDF 1065 P I K F EVK K + L +E S + W +DG+ + KP Sbjct: 2511 PPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRV 2570 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILR------DESCTAEVTVVELP---PEIITRL-QN 1115 G R L I+ T V D G Y C+ D+ + E P E + + Sbjct: 2571 RILGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEY 2630 Query: 1116 QKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 +++ + N A + A + W++ + + + + G+ ++ + +DAG Sbjct: 2631 REIVENNPAYLYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRA--EDAG 2688 Query: 1175 EYSC----EVGNSKCTAILTVEEPSI--NFTLRLPEFILVPANTDAYLTVEI-PDETLDV 1227 YSC EVG L V P + T L E + V AN+ L + + + Sbjct: 2689 RYSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTI 2748 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEF 1286 +W + + + ++ + R L + D Y CV + A ST KL V+ Sbjct: 2749 SWLQNGLPFSPSPRLQVLEN--GRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQG 2806 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P + + S V+L D +A P P W + + + + + +L Sbjct: 2807 EPGL--NPEQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEI--FLLPGTHTLQ 2862 Query: 1347 IKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 + +V+ D+G+Y N G H V+++V PS P ++ ++ C E Sbjct: 2863 LTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSC--ET 2920 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 + T+ + + Q + E I + + IQ+ + + + N A Sbjct: 2921 DAFPEPTVAWQ-KDGQPLVLPERIQAL-LGGQRLEIQDAQVSDKGLYSCRVSNA-----A 2973 Query: 1465 SETTEYYKVIKETKIQSPTVEKP-LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 E + + + PT E P + ++ + L+C GVP P VTW +D ++ Sbjct: 2974 GEAMRAFSLTVQV---PPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVE 3030 Query: 1524 T--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 + A+ Y C+A N E VV + P I + Sbjct: 3031 SSMARGVVSRGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAP--RIQSSGTT 3088 Query: 1582 QKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH 1639 Q+H V G + + ++G PPP V+W K+G+ L+ + S + +K+L+ S Sbjct: 3089 QEHSVLEGQDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASD 3148 Query: 1640 SSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 S YT A N AG + T+ V P+ +GP Sbjct: 3149 SGAYTCVARNAAGEDAKLYTVNVLVPPTIEQGP 3181 Score = 136 bits (330), Expect = 5e-30 Identities = 259/1231 (21%), Positives = 441/1231 (35%), Gaps = 117/1231 (9%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVE-KLRPKHTPDGSTVQFECQVE 534 D YT + +L E + V E S +F E ++ T ST+ EC+ Sbjct: 2485 DAGQYTCVVTNELGEAMKNYHV-EVLIPPSISKDDLFGEVSMKEVKTKVNSTLTLECESW 2543 Query: 535 GYPRPQITWFR--QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 P P I+W++ Q KP Q L I+ D+G + CVA N AG Sbjct: 2544 AVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSGRYLCVATNVAGED 2603 Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652 ++++ E +I+E P Y D Sbjct: 2604 DQDFNVLIQ------DFETPFWGEEARGGVTEYREIVE-------NNPAYLYCDTN---- 2646 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 A+P ++ W ++G D +S+ + VL+I V+ G Y+ A Sbjct: 2647 ------AVPAAELTW-YRG-----DRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKA 2694 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N GE L L + T + E ++ + V +V L V+GNP PTI+W +N Sbjct: 2695 SNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNG 2754 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP 832 P P + I + +V D Y AEN G T + T+ E P Sbjct: 2755 LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAG--STEKLFTLRVQGEPGLNP 2812 Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 ++IT ++ L V +P P +TWY++ +S E I G + L + Sbjct: 2813 -------EQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEIFL-LPGTH-TLQL 2863 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 T V +DSG Y C A N+AG+ V + V Q G +L C+T Sbjct: 2864 TRVQL-LDSGMYICEALNAAGRDH--KLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCET 2920 Query: 953 S--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML 1010 + W + + + + + + G+ D G+ C V + M Sbjct: 2921 DAFPEPTVAWQKDGQPLVLPERIQALLGGQ--RLEIQDAQVSDKGLYSCRVSNAAGEAMR 2978 Query: 1011 VVKETI---PEFIRKLQDFEVK-EKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDF 1065 T+ P F + + +L ++ A V W +D ++ + Sbjct: 2979 AFSLTVQVPPTFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVV 3038 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIIT--RLQNQKVNK 1120 + G +L + + G Y+C+ + A V V + P I + Q V + Sbjct: 3039 SRGG---RLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLE 3095 Query: 1121 GNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 G + E+ + V W KDGS + S L L + D D+G Y+C Sbjct: 3096 GQDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCV 3155 Query: 1180 VGN-----SKCTAILTVEEPSINFTLRLPE--FILVPANTDAYLTVEIP---DETLDVTW 1229 N +K + + P+I + PE LV D +++ P + V+W Sbjct: 3156 ARNAAGEDAKLYTVNVLVPPTIE---QGPEGAGTLVHRLGD-LVSMACPVRGSPPIHVSW 3211 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPP 1288 K + + + L S RTL ++ D +TCV A + + V PP Sbjct: 3212 LKDGLPLPLSHRTHLHS--SGRTLRVQLA---DSGTFTCVAASPAGVANRHFILQVLVPP 3266 Query: 1289 KI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 + +++ + + RGS V L + + P P W +K + P L Sbjct: 3267 VLEPAEFQNDVAVVRGSLVFLPCEARGSPLPFVSW------VKDGEPLLPQSLEHGPGLL 3320 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP--SPPGKPNILEIDSSSINICWDEP 1404 ++ E AG Y + G A +T++D P +P L + + + Sbjct: 3321 LEAAEAGHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDA 3380 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 T I + +++ W + ++ ++ + + + A S A Sbjct: 3381 RGTPTPNITW----HKDGRALSWPEDGQGARRVLRVEGVQVSDAGLYTCLA-----HSPA 3431 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 E + +++ + P + P + + L C P P++ W+R+G L+ Sbjct: 3432 GEVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQ-LVLECSVEADPAPEIEWHREGVLLQA 3490 Query: 1525 AKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ 1582 T E Y C A N G + V + + P + S Sbjct: 3491 DAHTQFPEEGRFLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNAS------ 3544 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSS 1641 V L+ +G+P P V W K+G L+ + +E +RI+ + + Sbjct: 3545 ---VNQTTLLPCQADGVPQPLVSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAG 3601 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 Y ASN AG+ L+V++ P+ GP Sbjct: 3602 HYLCLASNPAGSDRQGRDLQVFEPPAIAPGP 3632 Score = 130 bits (315), Expect = 3e-28 Identities = 245/1116 (21%), Positives = 418/1116 (37%), Gaps = 135/1116 (12%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIV--PDENISVAIESDMH 689 PP+ S +G + +LEC +P P + W ++G+ E++ P+++IS Sbjct: 668 PPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIW-YRGDLEMILAPEDSIS-------- 718 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +L+I V++ G YT AVN G+AS I L++ PQ++E + + V G Sbjct: 719 ---GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVG----HAPQLLELPQDVTVELG 771 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKAL-----PTKSDGDTHSITILKPKKVKDEGVYT 804 S +L+ + G+P PTITW + + L ++DG H L ++D G Y+ Sbjct: 772 RSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADGSLH----LDQALLEDAGRYS 827 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 N+ G + V+ +P IT E L + P P+I Sbjct: 828 CVVSNTAGSHHRDVQLVVQVKVPPRIQP----TATHHIT-NEGVPASLPCVASGVPTPTI 882 Query: 865 TWYRN-NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 TW + N + S + DG LVI + D+G Y C A+N+ G SS R+++ Sbjct: 883 TWTKETNALASRDPHYNVSKDGT---LVIPRPSVQ-DAGAYVCTATNAVGFSSQEMRLSV 938 Query: 924 DVEKVTFV--KH---------LQKSYETEE--------GKTVILEC--QTSHTVSTKWYH 962 ++E + KH + S+E ++ G V L+C Q S W Sbjct: 939 NMEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTK 998 Query: 963 NKKEISGM-DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST--MLVVKETIPEF 1019 + + + + D ++ G D G+ +C + S +++ +P Sbjct: 999 DSRHMLPITDRHHLLPPG---SLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQ 1055 Query: 1020 IRK-LQDFEVKEKDVAILE-VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 ++ + +V + L V S V W +DG ++ + G ++ Sbjct: 1056 VQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE---------GPEGSVHFA 1106 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVEL------PPEIIT--RLQNQKVNKGNKATFEIE 1129 G Y C + S +A V EL PP + R N G T E + Sbjct: 1107 AIQTSHAGTYRC---EASSSAGVDAWELDLRVLVPPSLREDGRRANVSGMAGQSLTLECD 1163 Query: 1130 LTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA- 1187 A + W K+G +I +L +DG + L D+G YSC N TA Sbjct: 1164 ANGFPAPEITWLKNGRQIPAVGSHRL-LDGAR-ALHFPRIQEGDSGLYSCRAENQAGTAQ 1221 Query: 1188 ----ILTVEEPSINFTLRLPEFI-LVPANTDAYL-TVEIPDETLDVTWYKKKSVIEDTEK 1241 +L + PS+ E + L A + T+ +P T V W K + E Sbjct: 1222 RDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVP--TPQVEWTKDGQPVFLGEP 1279 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKI--VDYEREYR 1298 + + + L I D+ Y CV A TK + PP I + E Sbjct: 1280 RVQLQE-DGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEVA 1338 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + G V L + + P P+ W + + T+ L +++ + +DAG Y Sbjct: 1339 VMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQLERAQGSDAGTY 1396 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGK---PNILEIDSSSINICWDEPENTGNSTIIYY 1415 + N G + + + P+ G P +++ + T+ +Y Sbjct: 1397 SCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVARGYPPPTVSWY 1456 Query: 1416 VVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 +D W+ S+++L S + A S A E +Y V Sbjct: 1457 HEGLPVVDRNGTWLGAGG---GVLSLESLGEASGGLYSCVA-----SSPAGEAVLHYSVE 1508 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYEN 1531 + Q V + L +TT + + L C G P P + W ++G ++L T E Sbjct: 1509 VQVAPQL-LVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEG 1567 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEW 1590 + C A N+ G + + + P V+ + E+I Sbjct: 1568 -TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFL--QPV 1624 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + G+P P + W+K+G + ++I+++ YT A+N Sbjct: 1625 TLRCAGTGVPTPSLRWWKDG----------VALAASGGSLQIEKVDLKDEGTYTCVATNL 1674 Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 AG S EV L+V P+ G V + SVT+E Sbjct: 1675 AGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLE 1710 Score = 122 bits (294), Expect = 1e-25 Identities = 213/958 (22%), Positives = 349/958 (36%), Gaps = 77/958 (8%) Query: 627 DILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 D+L IPP+ AQ V G+ LECR + +P P + W G+ + E V + Sbjct: 1225 DLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEP-RVQL 1283 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLK 742 + D VL+ITN EG Y VA + G+ + L+I PP + Sbjct: 1284 QEDGQ----VLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHA----PPTIWGSNETS 1335 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DE 800 + V +G V + G P P ITW K+ P+ +P+ T L+ ++ + D Sbjct: 1336 EVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQLERAQGSDA 1393 Query: 801 GVYTLKAENSEGIAETSAVITVEEPT--EENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 G Y+ KA N+ G+ E + + V P E E P R + T++ VAR Sbjct: 1394 GTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGP----RVVKAVAGRPLTLECVAR--G 1447 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P+++WY + G + L E G Y CVAS+ AG++ Sbjct: 1448 YPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLG---EASGGLYSCVASSPAGEAVLH 1504 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VST-KWYHNKKEISGMDHREII 976 V + V V T G+++ L C S + V T +W N + + Sbjct: 1505 YSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVT 1564 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF----IRKLQDFEVK-EK 1031 EG G+ C ++ + V+ ++ E I ++ + Sbjct: 1565 SEG--TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQ 1622 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI- 1090 V + T + W +DG + EK + DEG Y+C+ Sbjct: 1623 PVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQIEK-----------VDLKDEGTYTCVA 1671 Query: 1091 --LRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQF 1148 L ES + V +PP I L N+ V + T E L G V E+ Sbjct: 1672 TNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLEC-LASG---VPPPGKVWELGL 1727 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 N LKI C + G VG LTV P + P + Sbjct: 1728 GNDEPAVWGVLYSLLKI--CLV---GGLLAGVGCEGARLALTVLAPGCSSL--CPSLPSI 1780 Query: 1209 PANTDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 P+ T A +++W+K + I ++ + +D R L+I + D Y Sbjct: 1781 PSQTTAIFCSHPSSFQAFSNISWFKGRQPISAWDRAMVSTD--GRVLLIEQAQLSDAGSY 1838 Query: 1267 TCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 CV + +T+L+ + V PP I+ E+ + V L A P P W + Sbjct: 1839 RCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVANESVALECRSHAVPPPVLSWRKDG 1898 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-SPP 1384 + ++ S D A L + + E D G Y N G ++ N+ + P P Sbjct: 1899 RPLEPRPGVYLSAD--KALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNVWVPPVFPS 1956 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444 +P L + + I + + Q + E +S+ ++ + L Sbjct: 1957 REPRTLTVTEGHPARLSCDCRGVPFPK-ISWKKDGQPL-PGEGVSLAQVSAVGRLLY-LG 2013 Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + Y +++ S + V +I P +P +++ +E+ L C Sbjct: 2014 RAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPL--EPYADVSVVQDEEASLECN 2071 Query: 1505 FGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 G P P+VTW RDG + ++ + Y C+A N+ G E Sbjct: 2072 ATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHAGRYSCVAENEAGRAE 2129 Score = 119 bits (287), Expect = 8e-25 Identities = 212/1046 (20%), Positives = 383/1046 (36%), Gaps = 82/1046 (7%) Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P+P + W G+ + + V+ + ++L + + G Y VA N GE + Sbjct: 2352 PQPKVTWFKDGQPLASGDAHHVSPDG------ALLWVLHANLSSAGHYACVAANAIGEKT 2405 Query: 721 LPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP 779 L + + + + + V + L + P PTITW K+ P +AL Sbjct: 2406 KHFQLSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALN 2465 Query: 780 T-KSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR 838 + TH + IL +K +D G YT N G A + + V P + + Sbjct: 2466 NIQLLPGTHGLQILNAQK-EDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVS 2524 Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF------DGENIELVI 892 +E+ K T+ L P P+I+WY++ + + P + +T N +G +++ Sbjct: 2525 MKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNL-PEKPVTPNQRVRILGEGRLLQIQP 2583 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-----EGKTVI 947 T V DSG Y CVA+N AG+ V I + F + TE E Sbjct: 2584 TQVS---DSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAY 2640 Query: 948 LECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-----I 1000 L C T+ + + WY + +S D ++Q GR D G C + Sbjct: 2641 LYCDTNAVPAAELTWYRGDRPLSIEDGVSVLQGGR--VLQIPLVRAEDAGRYSCKASNEV 2698 Query: 1001 VKDQETSTMLVVKETI--PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK 1057 +D +LV+ + E +++ V L + A + W ++G Sbjct: 2699 GEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFS 2758 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQ 1114 P E G I L + V D Y C+ + + + E V+ P + Sbjct: 2759 PSPRLQVLE-NGRI--LQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEPGLNPEQI 2815 Query: 1115 NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 +N ++ V W+KDG + I L + G L++ L D+G Sbjct: 2816 TATLNSSVSLPCDVRAHPSPE-VTWYKDGWTLSLGEEIFL-LPG-THTLQLTRVQLLDSG 2872 Query: 1175 EYSCEVGNS--KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE---IPDETLDVTW 1229 Y CE N+ + ++ + + R + +LV A A L+ E P+ T V W Sbjct: 2873 MYICEALNAAGRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPT--VAW 2930 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPP 1288 K + E+ + + + L I+ D+ Y+C + +A + V+ PP Sbjct: 2931 QKDGQPLVLPERIQAL--LGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPP 2988 Query: 1289 KIVDYEREYRIK-RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 + E E + GS + L D P P W+ + ++ + S+ L + Sbjct: 2989 TFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVE--SSMARGVVSRGGRLQL 3046 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE---IDSSSINICWDEP 1404 ++ AG Y EN A + V +L P E ++ + + D Sbjct: 3047 SHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQL--DCE 3104 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 + + ++ + +D + + + + +++L+ + S + A N Sbjct: 3105 VDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNA----- 3159 Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITT---EPNEDIELTCIFGGVPQPKVTWYRDGK 1520 A E + Y V + PT+E+ + T + + + C G P V+W +DG Sbjct: 3160 AGEDAKLYTV---NVLVPPTIEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGL 3216 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 L + T+ + + C+A + G ++ + PV+ + Sbjct: 3217 PLPLSHRTHLH-SSGRTLRVQLADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQN 3275 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 G + G P P V W K+G L + E + ++ + H+ Sbjct: 3276 DVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLLPQ------SLEHGPGLLLEAAEAGHA 3329 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKP 1666 Y+ A + AG + L V D P Sbjct: 3330 GTYSCVAVSEAGEARRHFQLTVMDPP 3355 Score = 119 bits (286), Expect = 1e-24 Identities = 212/1025 (20%), Positives = 380/1025 (37%), Gaps = 104/1025 (10%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI---VPDENISVAIESD 687 G P + P+ V+ G LL CR P P I W +G++ + S+ + Sbjct: 754 GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW-HRGDDQPLGLRGSRHSIRADGS 812 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 +H+ ++L+ G Y+ V N G + L ++ K PP++ I Sbjct: 813 LHLDQALLE-------DAGRYSCVVSNTAGSHHRDVQLVVQV--KVPPRIQPTATHHITN 863 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +G L G P PTITW K + + + ++ V+D G Y A Sbjct: 864 EGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQDAGAYVCTA 923 Query: 808 ENSEGIAETSAVITVE-EP-------TEENAEPPLFINRFQE------ITVKEKGTIKLV 853 N+ G + ++V EP A+P + +N E +T K + L Sbjct: 924 TNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSHEADKPLRVTAKAGDEVTLD 983 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +P P +TW +++ + P ++ L V DSG Y+C ASN AG Sbjct: 984 CEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVS---DSGLYECTASNPAG 1040 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973 ++ + + V V+ + + G+ V L C + + +K ++ Sbjct: 1041 SATQYYILRVQVPPQ--VQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVA----- 1093 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ------ETSTMLVVKETIPEFIRKLQDFE 1027 + EG G +C E ++V ++ E R+ Sbjct: 1094 -LRGEGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVLVPPSLREDGRRANVSG 1152 Query: 1028 VKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 + + + LE + N A ++ W ++G I P + R L+ D G Sbjct: 1153 MAGQSLT-LECDANGFPAPEITWLKNGRQI-PAVGSH--RLLDGARALHFPRIQEGDSGL 1208 Query: 1087 YSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWF 1140 YSC +++ TA+ +V +PP ++ Q+V A E+E T G V W Sbjct: 1209 YSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWT 1268 Query: 1141 KDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EP 1194 KDG + +QL DG Q L+I + L D G Y C G L + P Sbjct: 1269 KDGQPVFLGEPRVQLQEDG--QVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHAPP 1326 Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFTLISDVKKRTL 1253 +I + E ++ + +L T D+TW+K ++ TE ++ R L Sbjct: 1327 TIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTE---VVYTRGGRQL 1383 Query: 1254 IIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 + + D Y+C +A + TT+L+V V + R + G +TL Sbjct: 1384 QLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLEC 1443 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 + +P P W + T + + L+++ + G+Y + G A Sbjct: 1444 VARGYPPPTVSWYHEGLPVVDRNGT--WLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 1501 Query: 1370 DVEMNVTILDKPS---PPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTT 1425 + +V + P G + + S+ + C+ + + + + Q Sbjct: 1502 VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCY------ASGSPVPTIQWLQNGHPA 1555 Query: 1426 EWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 E + ++T T+ I +++ + F A NE + A +++ + Sbjct: 1556 EELPGVHVTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGG-- 1613 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543 +NIT + + L C GVP P + W++DG L + + + Sbjct: 1614 -----ENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQ------IEKVDLK 1662 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+A N GE ++ + P I + N+ + + V E L + G+PP Sbjct: 1663 DEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLAS----GVPP 1718 Query: 1602 PEVIW 1606 P +W Sbjct: 1719 PGKVW 1723 Score = 119 bits (286), Expect = 1e-24 Identities = 214/1059 (20%), Positives = 388/1059 (36%), Gaps = 102/1059 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V+ S + L C ++ P P I+WL G P + V +E+ +L+++ + Sbjct: 2728 VNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQV-LENG-----RILQVSTAEVAD 2781 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 +Y VA N G L+++ GE P Q+ L S SV L V +P Sbjct: 2782 AASYMCVAENPAGSTEKLFTLRVQ-GEPGLNPEQITATLNS-------SVSLPCDVRAHP 2833 Query: 763 RPTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P +TW K+ + TH++ + + ++ D G+Y +A N+ G ++ Sbjct: 2834 SPEVTWYKDGWTLSLGEEIFLLPGTHTLQLTR-VQLLDSGMYICEALNAAGRDHKLVQLS 2892 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT-RNPVPSITWYRNNEIISPSETIT 880 V P P +R Q++ + G +++ T P P++ W ++ + + E I Sbjct: 2893 VLAP----GAP----SRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQ 2944 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 G+ +E+ V D G Y C SN+AG++ +T+ V TF + Sbjct: 2945 ALLGGQRLEIQDAQVS---DKGLYSCRVSNAAGEAMRAFSLTVQVPP-TFENPETEMVSR 3000 Query: 941 EEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 G ++L C + + W ++ + R ++ G G Sbjct: 3001 VAGSPLVLSCDVTGVPAPAVTWLKDRMPVESSMARGVVSRG--GRLQLSHLQPDQAGTYT 3058 Query: 999 CIVKD--QETSTMLVVKETIPEFIRK---LQDFEVKEKDVAILEVEINSETAD-VVWERD 1052 C+ ++ E VV + I+ Q+ V E L+ E++ + VVW +D Sbjct: 3059 CVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQDVQLDCEVDGQPPPYVVWLKD 3118 Query: 1053 GEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPE 1108 G + Y F G L +++ D G Y+C+ R+ E V +PP Sbjct: 3119 GSPLDESVGPYLWFYLNG--SSLVLKDLRASDSGAYTCVARNAAGEDAKLYTVNVLVPPT 3176 Query: 1109 IITRLQNQKV---NKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 I + G+ + + + V W KDG + S+ L G+ +++ Sbjct: 3177 IEQGPEGAGTLVHRLGDLVSMACPVRGSPPIHVSWLKDGLPLPLSHRTHLHSSGRTLRVQ 3236 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 L D+G ++C + A IL V P + + V + +L E Sbjct: 3237 -----LADSGTFTCVAASPAGVANRHFILQVLVPPVLEPAEFQNDVAVVRGSLVFLPCEA 3291 Query: 1221 PDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 L V+W ++D E S L++ Y+CV + + Sbjct: 3292 RGSPLPFVSW------VKDGEPLLPQSLEHGPGLLLEAAEAGHAGTYSCVAVSEAGEARR 3345 Query: 1280 KVEV-VEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 ++ V PP I D ++ E + G+ + LL D + P PN W + + + + P Sbjct: 3346 HFQLTVMDPPYIEDSDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRAL-----SWP 3400 Query: 1337 SIDSKSAS--LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 D + A L ++ V+ +DAG+Y + G + + + PN++ Sbjct: 3401 E-DGQGARRVLRVEGVQVSDAGLYTCLAHSPAGEVEKSFRIRV------QAPPNVIGSHG 3453 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + ++ VE EW + + Q + + + Sbjct: 3454 PRFVV-----GLAPGQLVLECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQ-- 3506 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 A++ D D S T + T + V +P + N+ L C GVPQP V Sbjct: 3507 ALSTADSGDYSCTA--HNAAGSTSLAFHVEVHRP-PTVNASVNQTTLLPCQADGVPQPLV 3563 Query: 1514 TWYRDGKKLKTAKATY----EN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 +W +DG L + E R Y C+A N G + + Sbjct: 3564 SWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAGHYLCLASNPAGSDRQGRDLQVF 3623 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 + P I ++ + G P P V W+K+G KL+ + ++ Sbjct: 3624 EPPAIAPGPSNLTLTAYTPAS--LPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSN 3681 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + ++E S+ + SN G + + V+ P+ Sbjct: 3682 ALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA 3720 Score = 112 bits (270), Expect = 9e-23 Identities = 198/904 (21%), Positives = 320/904 (35%), Gaps = 81/904 (8%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 T +G C G P P ITW ++T + S+D +Y+ TLVI +DAG Sbjct: 862 TNEGVPASLPCVASGVPTPTITWTKETNALA-SRD--PHYNVSKDGTLVIPRPSVQDAGA 918 Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640 + C A NA GF+S L V E ++ G + KP Sbjct: 919 YVCTATNAVGFSSQEMRLSV-------NMEPGFLLDPKHGATAKPRILVNGSHE--ADKP 969 Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY-CSVLKITN 699 G ++ L+C P P + W ++P I H+ L + Sbjct: 970 LRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLP-------ITDRHHLLPPGSLHLAQ 1022 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 + G Y A N G A+ +L+++ PPQV + + V GE+V L+ Sbjct: 1023 AQVSDSGLYECTASNPAGSATQYYILRVQV----PPQVQPGPRVLKVLVGEAVDLNCVAE 1078 Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 G+P P +TW K+ ++ +G H I + G Y +A +S G+ Sbjct: 1079 GSPEPRVTWSKDGVALRG--EGPEGSVHFAAI----QTSHAGTYRCEASSSAGVDAWELD 1132 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 + V P + R ++ ++ L P P ITW +N I P+ Sbjct: 1133 LRVLVPPSLRED-----GRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQI-PAVGS 1186 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 + DG L + E DSG Y C A N AG + + + + + Sbjct: 1187 HRLLDGAR-ALHFPRI-QEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVV 1244 Query: 940 TEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 G LEC+T T +W + + + + R +QE D G Sbjct: 1245 GLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQED-GQVLRITNSHLGDEGWY 1303 Query: 998 KCIV---KDQETSTMLVVKETIPEFIRKLQDFEVKEKD---VAILEVEINSETADVVWER 1051 +C+ Q+T + P + EV + V L T D+ W + Sbjct: 1304 QCVAFSPAGQQTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFK 1363 Query: 1052 DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPE 1108 DG+ + P + + + G R+L + D G YSC + E T V +PP Sbjct: 1364 DGDPLVP-STEVVYTRGG--RQLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPT 1420 Query: 1109 IITRLQNQKVNK---GNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 I + +V K G T E + +G V W+ +G + N L G L Sbjct: 1421 IEGTGEGPRVVKAVAGRPLTLEC-VARGYPPPTVSWYHEGLPVVDRNGTWLGAGG--GVL 1477 Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPE---FILVPANTDAYLTVE 1219 + G YSC + A+L E + L + E + YL Sbjct: 1478 SLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCY 1537 Query: 1220 IPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 + + W + E+ + S+ TL I + C + T Sbjct: 1538 ASGSPVPTIQWLQNGHPAEELPGVHVTSE--GTTLHIDHVELGHAGLFACQATNEAGTAA 1595 Query: 1279 LKVE--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 +VE V E P ++ VTL P P+ W + Sbjct: 1596 AEVELSVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDG----------V 1645 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNILEIDSS 1395 ++ + SL I+KV+ D G Y N G + E+ + +L P+ PG N ++++ Sbjct: 1646 ALAASGGSLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENA 1705 Query: 1396 SINI 1399 S+ + Sbjct: 1706 SVTL 1709 Score = 111 bits (266), Expect = 3e-22 Identities = 172/783 (21%), Positives = 302/783 (38%), Gaps = 70/783 (8%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+ +P P ITW + + + Q+ + L ++ EDAG +TCV N G Sbjct: 2442 CETRAFPTPTITWMKDGVPFEALNNIQLLPGTHGLQILNAQK---EDAGQYTCVVTNELG 2498 Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 A + V P S D L G K K S Sbjct: 2499 EAMKNYHVEVLIPPS------------------ISKDDLFGEVSMKEVKTKV-----NST 2535 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + LEC A+P P I+W +K + +P++ ++ + +L+I + G Y Sbjct: 2536 LTLECESWAVPPPTISW-YKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSGRYLC 2594 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV-----ILSAQVVGNPRPT 765 VA N GE + I+ + E P E + + E V L P Sbjct: 2595 VATNVAGEDDQDFNVLIQ--DFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVPAAE 2652 Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 +TW + ++P+ S + + + +D G Y+ KA N G + V P Sbjct: 2653 LTWYRGDRPLSIEDGVSVLQGGRVLQIPLVRAEDAGRYSCKASNEVGEDWLHYELLVLTP 2712 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 E + +E+TV T+ L V NP P+I+W +N SPS + +G Sbjct: 2713 PVILGETEELV---EEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENG 2769 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 +++ V D+ Y CVA N AG + T+ V+ + Q + + Sbjct: 2770 RILQVSTAEV---ADAASYMCVAENPAGSTE--KLFTLRVQGEPGLNPEQITATLNSSVS 2824 Query: 946 VILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 + + + + WY + +S + EI D G+ C + Sbjct: 2825 LPCDVRAHPSPEVTWYKDGWTLSLGE--EIFLLPGTHTLQLTRVQLLDSGMYICEALNAA 2882 Query: 1006 TSTMLVVKETI--PEFIRKLQDFE-VKEKDVAILEVEINS-ETADVVWERDGE-IIKPKK 1060 +V+ ++ P + QD V D A+L E ++ V W++DG+ ++ P++ Sbjct: 2883 GRDHKLVQLSVLAPGAPSRPQDVVLVSAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPER 2942 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIITRLQNQK 1117 + ++L I++ V D+G YSC + + E+ A V++PP + + Sbjct: 2943 ----IQALLGGQRLEIQDAQVSDKGLYSCRVSNAAGEAMRAFSLTVQVPP-TFENPETEM 2997 Query: 1118 VNK--GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 V++ G+ ++T A V W KD ++ S + + + +L++ D AG Sbjct: 2998 VSRVAGSPLVLSCDVTGVPAPAVTWLKDRMPVESS--MARGVVSRGGRLQLSHLQPDQAG 3055 Query: 1175 EYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VT 1228 Y+C N++ A + + P I + E ++ D L E+ + V Sbjct: 3056 TYTCVAENAQAEAHKDFVVAVLVAPRIQSSGTTQEHSVLEGQ-DVQLDCEVDGQPPPYVV 3114 Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK-STTKLKVEVVEFP 1287 W K S ++++ L + +L+++ D YTCV +A KL V P Sbjct: 3115 WLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVARNAAGEDAKLYTVNVLVP 3174 Query: 1288 PKI 1290 P I Sbjct: 3175 PTI 3177 Score = 109 bits (261), Expect = 1e-21 Identities = 192/909 (21%), Positives = 344/909 (37%), Gaps = 84/909 (9%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E AP +E + G + C+ G+P P ITW R + + D Sbjct: 752 EVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADG 811 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 +L + + EDAG ++CV N AG +L+V+ + Sbjct: 812 --SLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVPAS 869 Query: 625 XADILEGIPP---TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 + G+P T++K+ A + + + + IP P + G + N + Sbjct: 870 LPCVASGVPTPTITWTKETNALASRDPHYNVSKDGTLVIPRPSVQ--DAGAYVCTATN-A 926 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 V S M SV + G + + G + P +L + E + +PL Sbjct: 927 VGF-SSQEMRLSV-------NMEPG---FLLDPKHGATAKPRILVNGSHEAD-----KPL 970 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801 + + + G+ V L + G+P P +TW K+++ + + + L +V D G Sbjct: 971 R-VTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSG 1029 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 +Y A N G A ++ V+ P + P R ++ V E + VA +P Sbjct: 1030 LYECTASNPAGSATQYYILRVQVPPQVQPGP-----RVLKVLVGEAVDLNCVAE--GSPE 1082 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P +TW ++ + +G + + + +G Y+C AS+SAG + + Sbjct: 1083 PRVTWSKDG--------VALRGEGPEGSVHFAAIQTS-HAGTYRCEASSSAGVDAWELDL 1133 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979 + V + + G+++ LEC + + + W N ++I + ++ Sbjct: 1134 RVLVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGA 1193 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAIL 1036 R D G+ C ++Q + + P + EV A Sbjct: 1194 R--ALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGA 1251 Query: 1037 EVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 E+E + T V W +DG+ + + + ++ G + L I N+ + DEG Y C+ Sbjct: 1252 ELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV--LRITNSHLGDEGWYQCVAFS 1309 Query: 1094 ES--CTAEVTV-VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI 1146 + T + + + PP I V +G+ F E +G + WFKDG + Sbjct: 1310 PAGQQTKDFQLRIHAPPTIWGSNETSEVAVMEGHPVWFLCE-ARGVPTPDITWFKDGDPL 1368 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLR 1201 S + T G+ +L++ DAG YSC+ N+ K T + P+I T Sbjct: 1369 VPSTEVVYTRGGR--QLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGE 1426 Query: 1202 LPEFILVPANTDAYLTVE-----IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIR 1256 P +V A LT+E P T V+WY + + D L L + Sbjct: 1427 GPR--VVKAVAGRPLTLECVARGYPPPT--VSWYHEGLPVVDRNGTWL--GAGGGVLSLE 1480 Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR--GSDVTLLVDYQA 1313 E Y+CV L V V+ P+++ E ++ G + L Sbjct: 1481 SLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASG 1540 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P +W+ N ++ + S+ +L I VE AG++ + N G A E+ Sbjct: 1541 SPVPTIQWLQNGHPAEELPGV--HVTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEV 1598 Query: 1374 NVTILDKPS 1382 +++ + PS Sbjct: 1599 ELSVHELPS 1607 Score = 106 bits (254), Expect = 8e-21 Identities = 223/1069 (20%), Positives = 387/1069 (36%), Gaps = 95/1069 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP P+ V G + L C PEP + W G + + E +H Sbjct: 1052 VPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDGVALRGE-----GPEGSVHFA 1106 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR--QG 749 ++ GTY A + G + + L++ PP + E + V G Sbjct: 1107 A-------IQTSHAGTYRCEASSSAGVDAWELDLRVLV----PPSLREDGRRANVSGMAG 1155 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 +S+ L G P P ITW KN + + A+ + D + D G+Y+ +AEN Sbjct: 1156 QSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEGDSGLYSCRAEN 1215 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G A+ + V P L QE+ +L R P P + W ++ Sbjct: 1216 QAGTAQRDFDLLVLIPPSV-----LGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWTKD 1270 Query: 870 NEIISPSETITQ-NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + E Q DG+ + + +++ D G Y+CVA + AG+ + ++ I Sbjct: 1271 GQPVFLGEPRVQLQEDGQVLRITNSHLG---DEGWYQCVAFSPAGQQTKDFQLRIHAPPT 1327 Query: 929 TFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 + + EG V C+ T W+ + + + E++ Sbjct: 1328 IWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEVVYTRGGRQLQL 1385 Query: 987 XXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVA----ILE- 1037 D G C + E +T L V +P I + K VA LE Sbjct: 1386 ERAQGSDAGTYSCKASNAVGVVEKTTRLEVY--VPPTIEGTGEGPRVVKAVAGRPLTLEC 1443 Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 V V W +G + + + G + L + + G YSC+ + Sbjct: 1444 VARGYPPPTVSWYHEGLPVVDRNGTW-LGAGGGV--LSLESLGEASGGLYSCVASSPAGE 1500 Query: 1098 A----EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151 A V V P ++ Q ++ + G + ++W ++G + Sbjct: 1501 AVLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGHPAEELPG 1560 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 + +T +G L I +L AG ++C+ N TA VE S++ LP ++V Sbjct: 1561 VHVTSEGTT--LHIDHVELGHAGLFACQATNEAGTAAAEVEL-SVH---ELPSVVIVGGE 1614 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 ++ T S+ + L + +L I K D+ YTCV Sbjct: 1615 NITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAAS--GGSLQIEKVDLKDEGTYTCVAT 1672 Query: 1272 DAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + ++ +V + V PP I + + VTL P P W + Sbjct: 1673 NLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLASGVPPPGKVWELG------ 1726 Query: 1331 CKHTKPSIDSKSASLT-IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + +P++ SL I V AG+ G + +T+L P++ Sbjct: 1727 LGNDEPAVWGVLYSLLKICLVGGLLAGV---------GCEGARLALTVLAPGCSSLCPSL 1777 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 I S + I P + + I + Q I + V + I+ + + + Sbjct: 1778 PSIPSQTTAIFCSHPSSFQAFSNISWFKGRQPISAWDRAMVSTDGRVLL-IEQAQLSDAG 1836 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 +R A N V +TE ++ P++ +N++ NE + L C VP Sbjct: 1837 SYRCVASNVVG------STELQYSLRVNA--PPSILGEEQNVSVVANESVALECRSHAVP 1888 Query: 1510 QPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 P ++W +DG+ L+ Y ++ Y C A N G E + + Sbjct: 1889 PPVLSWRKDGRPLEPRPGVYLSADKALLEVDRAEVGDTGRYTCEALNQVGRSEKHYNLNV 1948 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 PV S E G ++ G+P P++ W K+G L + ++ + + Sbjct: 1949 WVPPVFP-SREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGE---GVSLAQVS 2004 Query: 1628 SVIRIKELKRSHSSK---YTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 +V R+ L R+ ++ YT E SN AG SS + L VY P + GP+ Sbjct: 2005 AVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVY-VPPRIAGPL 2052 Score = 102 bits (244), Expect = 1e-19 Identities = 158/779 (20%), Positives = 308/779 (39%), Gaps = 72/779 (9%) Query: 632 IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PPTF + P+ + V GS ++L C + +P P + WL ++ +P E+ ++ + Sbjct: 2986 VPPTF-ENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWL---KDRMPVES---SMARGVV 3038 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L++++++ Q GTYT VA N + EA V+ + + Q + V +G Sbjct: 3039 SRGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAPRI--QSSGTTQEHSVLEG 3096 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKA 807 + V L +V G P P + W K+ P+ P S +LK + D G YT A Sbjct: 3097 QDVQLDCEVDGQPPPYVVWLKDGSPLDESVGPYLWFYLNGSSLVLKDLRASDSGAYTCVA 3156 Query: 808 ENSEGI-AETSAVITVEEPT-EENAEPP-LFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 N+ G A+ V + PT E+ E ++R ++ + + V +P + Sbjct: 3157 RNAAGEDAKLYTVNVLVPPTIEQGPEGAGTLVHRLGDL-------VSMACPVRGSPPIHV 3209 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 +W ++ + S + G + + + DSG + CVA++ AG ++ + + Sbjct: 3210 SWLKDGLPLPLSHRTHLHSSGRTLRVQLA------DSGTFTCVAASPAGVANRHFILQVL 3263 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXX 982 V V Q G V L C+ S W + + + + ++ G Sbjct: 3264 VPPVLEPAEFQNDVAVVRGSLVFLPCEARGSPLPFVSWVKDGEPLL----PQSLEHG--P 3317 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKL-QDFEVKEKDVAILEVE 1039 G C+ + + T+ P +I Q E+ LE+ Sbjct: 3318 GLLLEAAEAGHAGTYSCVAVSEAGEARRHFQLTVMDPPYIEDSDQPEELLLTPGTPLELL 3377 Query: 1040 INSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 ++ T ++ W +DG + + + +G R L + V D G Y+C+ + Sbjct: 3378 CDARGTPTPNITWHKDGRAL-----SWPEDGQGARRVLRVEGVQVSDAGLYTCLAHSPAG 3432 Query: 1097 TAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDAL--VRWFKDGSEIQFSN 1150 E + V+ PP +I + V +E + + D + W ++G +Q Sbjct: 3433 EVEKSFRIRVQAPPNVIGSHGPRFVVGLAPGQLVLECSVEADPAPEIEWHREGVLLQADA 3492 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE---EPSINFTLRLPEF 1205 H Q +G+ L++ D+G+YSC N+ + L VE P++N ++ + Sbjct: 3493 HTQFPEEGR--FLQLQALSTADSGDYSCTAHNAAGSTSLAFHVEVHRPPTVNASVN--QT 3548 Query: 1206 ILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQC 1264 L+P D +P V+W K ++ + ++ L + + L I+ +D Sbjct: 3549 TLLPCQADG-----VPQPL--VSWLKDGVPLDPGSTRWVLAREGLREGLRIQPVLAEDAG 3601 Query: 1265 EYTCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y C+ + + + ++ F PP I + + +L + P+P W Sbjct: 3602 HYLCLASNPAGSDRQGRDLQVFEPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWK 3661 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 + + + S +L +++ D+ +++ + N G A VT+ P+ Sbjct: 3662 DGQKLDFRLQQGAYRLLPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA 3720 Score = 101 bits (241), Expect = 3e-19 Identities = 80/320 (25%), Positives = 130/320 (40%), Gaps = 20/320 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P P + ++LL C IP P IAW +G VP N + + Sbjct: 3810 PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLS-VPAANPGAGTQV---LPGG 3865 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+I +V G Y +A N G A V K + + PP + L + + +G + Sbjct: 3866 QLRIIHVSPEDAGNYFCLAQNSAGSA----VRKTRLVVQVPPAIKTGLPDLSITEGAHAL 3921 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L G+P P +TW K+ +PV K ++K + +D G YT AEN+ G Sbjct: 3922 LPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A +T+ P+F + +++ + L +P P I W NN ++ Sbjct: 3982 ARRRVHLTI-------LALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLV 4034 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + +E +++ G ++ V + DSG Y C A N G+ A + V+ V + Sbjct: 4035 TATEGVSEQDGGSTLQRVAVTRE---DSGTYVCWAENRVGRVQ--AVSFVHVKGVPVFQV 4089 Query: 934 LQKSYETEEGKTVILECQTS 953 + G +V L CQ S Sbjct: 4090 KPQDVTVRSGDSVALRCQAS 4109 Score = 95.9 bits (228), Expect = 1e-17 Identities = 82/349 (23%), Positives = 142/349 (40%), Gaps = 26/349 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P S ++Q +G ++ + C P P I+W +G + D + V + Sbjct: 579 PQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQG------- 631 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I V G+Y+ A N G + L +PP V ++ +GE + Sbjct: 632 TLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYT----DPPSVSAVNGVVLAAKGEEAV 687 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L + G P P + W + + + P S I +++ + D GVYT +A N G Sbjct: 688 LECEATGVPPPRVIWYRGDLEMILAPEDSISGMLRIPVVRER---DAGVYTCRAVNELG- 743 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + SA I +E P + Q++TV+ + L R T +P+P+ITW+R ++ Sbjct: 744 -DASAEIRLEV-----GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQP 797 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + + L + E D+G Y CV SN+AG ++ + V+ ++ Sbjct: 798 LGLRGSRHSIRADG-SLHLDQALLE-DAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQP 855 Query: 934 LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-HREIIQEG 979 + T EG L C S T + W ++ D H + ++G Sbjct: 856 TATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG 904 Score = 95.1 bits (226), Expect = 2e-17 Identities = 155/727 (21%), Positives = 279/727 (38%), Gaps = 79/727 (10%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +I K +EGTY AV+R G + + TG PPQ++ P+ ++ V GE+ ILS Sbjct: 453 EIPRASKAEEGTYECTAVSRAGTGRAKTQIVV-TGP--PPQLV-PVPNVTVSPGETAILS 508 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 V+ +TW ++ + + A + ++ D G Y A NS G+ Sbjct: 509 CLVLSEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTR 568 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 S + V E + + R Q + + +++ + P P I+W R + Sbjct: 569 ASVWLLVREAPQVSIH-----TRSQRFS--QGMEVRVRCSASGYPAPHISWSREGRALQE 621 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 + + G L+I V E D+G Y C A+N G+ VT+ V + Sbjct: 622 DSRVRVDAQG---TLIIQGVAPE-DAGSYSCQAANEIGRDEE--TVTLYYTDPPSVSAVN 675 Query: 936 KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 +G+ +LEC+ + + WY E+ I D Sbjct: 676 GVVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI-----SGMLRIPVVRERD 730 Query: 994 VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVW 1049 GV C ++ ++ + P+ + QD V+ A+L + W Sbjct: 731 AGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW 790 Query: 1050 ER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-----VTVV 1103 R D + + + +++ G L++ + D G YSC++ + + + V V Sbjct: 791 HRGDDQPLGLRGSRHSIRADG---SLHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQV 847 Query: 1104 ELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSN-HIQLTIDGKKQ 1161 ++PP I + N+G A+ + + W K+ + + + H ++ DG Sbjct: 848 KVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG--- 904 Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE-EPSI----NFTLRLPEFILVPANT 1212 L I + DAG Y C VG S L+V EP ILV + Sbjct: 905 TLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNMEPGFLLDPKHGATAKPRILVNGSH 964 Query: 1213 DA----YLTVEIPDE-TLD----------VTWYK-KKSVIEDTEKFTLISDVKKRTLIIR 1256 +A +T + DE TLD VTW K + ++ T++ L+ +L + Sbjct: 965 EADKPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLL---PPGSLHLA 1021 Query: 1257 KCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315 + D Y C + A S T+ + V+ PP++ R ++ G V L + P Sbjct: 1022 QAQVSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSP 1081 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 +P W + ++ + S+ ++ + AG Y+ ++ G E+++ Sbjct: 1082 EPRVTWSKDGVALRG--------EGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDL 1133 Query: 1376 TILDKPS 1382 +L PS Sbjct: 1134 RVLVPPS 1140 Score = 93.5 bits (222), Expect = 6e-17 Identities = 127/570 (22%), Positives = 218/570 (38%), Gaps = 48/570 (8%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTV 1191 V WFKDG + + ++ DG L + +L AG Y+C N+ K + + Sbjct: 2356 VTWFKDGQPLASGDAHHVSPDGAL--LWVLHANLSSAGHYACVAANAIGEKTKHFQLSVL 2413 Query: 1192 EEPSINFTLR--LPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDV 1248 P+I + E + V N L E T +TW K E L+ Sbjct: 2414 VVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFEALNNIQLLPGT 2473 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYE-------REYRI 1299 L I ++D +YTCV+ + ++ VEV+ PP I + +E + Sbjct: 2474 --HGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVL-IPPSISKDDLFGEVSMKEVKT 2530 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT---KPSIDSKSASLTIKKVENTDAG 1356 K S +TL + A P P W + + + + T + I + L I+ + +D+G Sbjct: 2531 KVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQRVRILGEGRLLQIQPTQVSDSG 2590 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSP-------PGKPNILEIDSSSINICWDEPENTGN 1409 Y N G D + NV I D +P G EI ++ + + Sbjct: 2591 RYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVTEYREIVENNPAYLYCDTNAVPA 2650 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + + +Y + + + + +SV + I ++ + R+ A NEV + Sbjct: 2651 AELTWYRGD-RPLSIEDGVSVLQGGRV-LQIPLVRAEDAGRYSCKASNEV----GEDWLH 2704 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--A 1527 Y ++ + E+ ++ +T N + L C G P P ++W ++G + Sbjct: 2705 YELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNPAPTISWLQNGLPFSPSPRLQ 2764 Query: 1528 TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 EN Y C+A N G E + +Q +P ++ E I + Sbjct: 2765 VLENGRILQVSTAEVADAASYMCVAENPAGSTEKLFTLRVQGEP--GLNPEQITA--TLN 2820 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + + P PEV WYK+G L +E I T +++ ++ S Y EA Sbjct: 2821 SSVSLPCDVRAHPSPEVTWYKDGWTLSLGEE--IFLLPGTHTLQLTRVQLLDSGMYICEA 2878 Query: 1648 SNTAGTSSVEVTLKVY--DKPSKPEGPVIM 1675 N AG V L V PS+P+ V++ Sbjct: 2879 LNAAGRDHKLVQLSVLAPGAPSRPQDVVLV 2908 Score = 92.7 bits (220), Expect = 1e-16 Identities = 104/492 (21%), Positives = 194/492 (39%), Gaps = 31/492 (6%) Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DT 1239 G +K ++T P + + +P + P T + + + ++TW + V+ T Sbjct: 476 GRAKTQIVVTGPPPQL---VPVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSAST 532 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR 1298 + T ++D+ +L +R T D Y C+ ++ T+ V + V P++ + R R Sbjct: 533 GRVTQLADL---SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQR 589 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +G +V + +P P+ W + +++ + +D++ +L I+ V DAG Y Sbjct: 590 FSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVR--VDAQG-TLIIQGVAPEDAGSY 646 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + N G + + + D PS ++ + E +I+Y + Sbjct: 647 SCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYRGD 706 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + I E S+ + + I ++ + + AVNE + DAS ++ E Sbjct: 707 LEMILAPE-DSISGMLR----IPVVRERDAGVYTCRAVNE--LGDASA-----EIRLEVG 754 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK---LKTAKATYENRXXX 1535 +E P +++T E L C G P P +TW+R + L+ ++ + Sbjct: 755 HAPQLLELP-QDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRGSRHSIRADGSL 813 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y C+ N G + +Q K I G + V Sbjct: 814 HLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHITNEGVPASLPCV 873 Query: 1596 IEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 G+P P + W K N L D YN+ +K+ T VI ++ + Y A+N G S Sbjct: 874 ASGVPTPTITWTKETNALASRDPHYNV-SKDGTLVIPRPSVQ--DAGAYVCTATNAVGFS 930 Query: 1655 SVEVTLKVYDKP 1666 S E+ L V +P Sbjct: 931 SQEMRLSVNMEP 942 Score = 88.2 bits (209), Expect = 2e-15 Identities = 174/894 (19%), Positives = 313/894 (35%), Gaps = 80/894 (8%) Query: 823 EEPTEENAEPPLFINRF---QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 EE E PP I +T + L T P P I W+R E +SP E Sbjct: 2217 EETRREYLVPPELIGDLGPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGEN- 2275 Query: 880 TQNFDGENIE---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 T G+ I L +T E D G Y C+ASN AG++ V + + H + Sbjct: 2276 TYLLAGKKISGWMLKLTRA-QEQDRGLYSCLASNEAGEARRDFSVEV-LGTSPRGSHGRP 2333 Query: 937 SYETEEGKTVILECQTSH-TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + T H W+ + + ++ D + +G G Sbjct: 2334 PILPSSLRASGSGPSTGHPQPKVTWFKDGQPLASGDAHHVSPDG--ALLWVLHANLSSAG 2391 Query: 996 VIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAI-----LEVEINS-ETAD 1046 C+ + ++T + +P + +D +E V I L E + T Sbjct: 2392 HYACVAANAIGEKTKHFQLSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPT 2451 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103 + W +DG + N + L I N D G+Y+C++ +E A V Sbjct: 2452 ITWMKDGVPFEALNN---IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEV 2508 Query: 1104 ELPPEII-------TRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGS---EIQFSNHI 1152 +PP I ++ K + T E E + W+KDG E + + Sbjct: 2509 LIPPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPTISWYKDGQNLPEKPVTPNQ 2568 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAILTVEEPSINFTLR--LP 1203 ++ I G+ + L+I + D+G Y C N I E P R + Sbjct: 2569 RVRILGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARGGVT 2628 Query: 1204 EFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE 1260 E+ + N AYL T +P ++TWY+ + + +++ R L I Sbjct: 2629 EYREIVENNPAYLYCDTNAVP--AAELTWYRGDRPLSIEDGVSVLQG--GRVLQIPLVRA 2684 Query: 1261 DDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQAFP 1315 +D Y+C + L E++ P ++ + E + S V+L P Sbjct: 2685 EDAGRYSCKASNEVGEDWLHYELLVLTPPVILGETEELVEEVTVNANSTVSLHCPVLGNP 2744 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P W+ N + + + L + E DA Y EN G + + Sbjct: 2745 APTISWLQNG--LPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPAGSTEKLFTL 2802 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 + +P I +SS+++ D + S + + + + E I + T Sbjct: 2803 RVQGEPG-LNPEQITATLNSSVSLPCDVRAHP--SPEVTWYKDGWTLSLGEEIFLLPGTH 2859 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 T + ++ S + A+N +K+++ + + +P + Sbjct: 2860 T-LQLTRVQLLDSGMYICEALNAAG--------RDHKLVQLSVLAPGAPSRPQDVVLVSA 2910 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAF 1553 + L+C P+P V W +DG+ L + Y C Sbjct: 2911 GDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQRLEIQDAQVSDKGLYSCRVS 2970 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612 N GE + + +Q P T N + + +V G +++ + G+P P V W K+ Sbjct: 2971 NAAGEAMRAFSLTVQVPP--TFENPETEMVSRVAGSPLVLSCDVTGVPAPAVTWLKDRMP 3028 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 +E+ + + + +++ L+ + YT A N + + + V P Sbjct: 3029 VESSMARGVVS--RGGRLQLSHLQPDQAGTYTCVAENAQAEAHKDFVVAVLVAP 3080 Score = 88.2 bits (209), Expect = 2e-15 Identities = 99/448 (22%), Positives = 171/448 (38%), Gaps = 36/448 (8%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C +P P ++W G + N S L+I G YT Sbjct: 3736 VVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYRVSPS------GALEIGQALPIHTGRYTC 3789 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWC 769 A N G A +VL ++ V++PL S++ E V+L + G PRP+I W Sbjct: 3790 AARNAAGMAHKHVVLTVQAS-----PVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQ 3844 Query: 770 KNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTE 827 K V A + L+ V +D G Y A+NS G A + V+ Sbjct: 3845 KEGLSVPAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQ---- 3900 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQNFDGE 886 PP ++++ E L T +P P +TW ++ + +S ++ T G Sbjct: 3901 ---VPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKGKFTIQPSG- 3956 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 EL++ N +S+ D+G Y C A N+ G++ +TI V +S + + Sbjct: 3957 --ELLVKNSESQ-DAGTYTCTAENAVGRARRRVHLTILALPVFTTLPGDRSLRLGDKLWL 4013 Query: 947 ILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--- 1003 + S T W N + ++ + + ++ D G C ++ Sbjct: 4014 HCAARGSPTPQIGWTVNNRLVTATE--GVSEQDGGSTLQRVAVTREDSGTYVCWAENRVG 4071 Query: 1004 QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNK 1062 + + V + +P F K QD V+ D L + + E A + W R G+ ++ + Sbjct: 4072 RVQAVSFVHVKGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRL 4131 Query: 1063 YDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 L++ D G Y C+ Sbjct: 4132 QTLPD----GSLWLERVEARDAGPYECV 4155 Score = 84.6 bits (200), Expect = 3e-14 Identities = 73/320 (22%), Positives = 130/320 (40%), Gaps = 19/320 (5%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 LI +A LSD GS V + + PP+ + + V + LECR Sbjct: 1826 LIEQAQLSDAGSYRCVASNVVGSTELQYS-LRVNAPPSILGEEQNVSVVANESVALECRS 1884 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 A+P P ++W G + P + ++ + ++L++ + G YT A+N+ G Sbjct: 1885 HAVPPPVLSWRKDGRPLEPRPGVYLSADK------ALLEVDRAEVGDTGRYTCEALNQVG 1938 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-- 775 + L + P + EP +++ V +G LS G P P I+W K+ +P+ Sbjct: 1939 RSEKHYNLNVWVPPVFPSR--EP-RTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPG 1995 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 + + + L + EG YT + N G + + V P A P Sbjct: 1996 EGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVP-PRIAGP--- 2051 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 + + +++V + L T P P +TW R+ + P + G+++ + Sbjct: 2052 LEPYADVSVVQDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHV---ER 2108 Query: 896 DSEIDSGDYKCVASNSAGKS 915 +G Y CVA N AG++ Sbjct: 2109 AQPAHAGRYSCVAENEAGRA 2128 Score = 81.8 bits (193), Expect = 2e-13 Identities = 72/285 (25%), Positives = 116/285 (40%), Gaps = 21/285 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP + EG+ LL C PEP + W G+ + + I+ Sbjct: 3901 VPPAIKTGLPDLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKG-KFTIQPS---- 3955 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L + N + GTYT A N G A + L I P +R G+ Sbjct: 3956 -GELLVKNSESQDAGTYTCTAENAVGRARRRVHLTILA----LPVFTTLPGDRSLRLGDK 4010 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L G+P P I W NN+ V A S+ D S +D G Y AEN Sbjct: 4011 LWLHCAARGSPTPQIGWTVNNRLVTATEGVSEQDGGSTLQRVAVTREDSGTYVCWAENRV 4070 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G + + + V+ P+F + Q++TV+ ++ L + + P P++ W R + Sbjct: 4071 GRVQAVSFVHVKGV-------PVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQ 4123 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + S+ + DG L + V++ D+G Y+CVA N G ++ Sbjct: 4124 PVRASQRLQTLPDG---SLWLERVEAR-DAGPYECVAHNLLGSAT 4164 Score = 79.0 bits (186), Expect = 1e-12 Identities = 159/783 (20%), Positives = 280/783 (35%), Gaps = 69/783 (8%) Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 S +P+ + G+ + L C P P+I W G + E+ A VL+ Sbjct: 3360 SDQPEELLLTPGTPLELLCDARGTPTPNITWHKDGRALSWPEDGQGARR--------VLR 3411 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQGESVI 753 + V+ G YT +A + GE ++++ PP VI P + + G+ ++ Sbjct: 3412 VEGVQVSDAGLYTCLAHSPAGEVEKSFRIRVQA----PPNVIGSHGPRFVVGLAPGQ-LV 3466 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 L V +P P I W + ++A + L+ D G Y+ A N+ G Sbjct: 3467 LECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRFLQLQALSTADSGDYSCTAHNAAGS 3526 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + + V P NA +N+ + + G P P ++W ++ + Sbjct: 3527 TSLAFHVEVHRPPTVNAS----VNQTTLLPCQADGV----------PQPLVSWLKDGVPL 3572 Query: 874 SPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 P T +G L I V +E D+G Y C+ASN AG G + + Sbjct: 3573 DPGSTRWVLAREGLREGLRIQPVLAE-DAGHYLCLASNPAGSDRQGRDLQVFEPPAIAPG 3631 Query: 933 HLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX 992 + ++ E S W+ + +++ + + Sbjct: 3632 PSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLDFRLQQGAYRLLPSNALLLEEPSPQ 3691 Query: 993 DVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQ-DFEVKEKDVAILEVEINSETADVV- 1048 D + +C+V + E + V +P I Q DF +L A VV Sbjct: 3692 DSALFECVVSNGVGEARKLYWVTVHVPPAIADDQTDFTATIMAPVVLTCHSTGVPAPVVS 3751 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VTVVE 1104 W + G + + N Y G L I G Y+C R+ + A +TV Sbjct: 3752 WSKAGTRLGVRGNGYRVSPSG---ALEIGQALPIHTGRYTCAARNAAGMAHKHVVLTVQA 3808 Query: 1105 LP-----PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 P P ++ + ++V +A+ + + + W K+G + +N T Sbjct: 3809 SPVVKPLPSVVWAVAKEEVLLPCEAS---GIPRPS--IAWQKEGLSVPAANPGAGTQVLP 3863 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAY 1215 +L+I +DAG Y C NS +A+ L V+ P T LP+ + Sbjct: 3864 GGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKT-GLPDLSITEGAHALL 3922 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 VTW K + + KFT+ L+++ D YTC +A Sbjct: 3923 PCTATGSPEPKVTWEKDGQPVSGAKGKFTI---QPSGELLVKNSESQDAGTYTCTAENAV 3979 Query: 1275 STTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + +V + P + ++ G + L + P P W VN++++ + Sbjct: 3980 GRARRRVHLTILALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATE- 4038 Query: 1334 TKPSIDSKSASLTIKKVENT--DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + + T+++V T D+G Y EN G V + P KP + Sbjct: 4039 ---GVSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVHVKGVPVFQVKPQDVT 4095 Query: 1392 IDS 1394 + S Sbjct: 4096 VRS 4098 Score = 78.2 bits (184), Expect = 2e-12 Identities = 154/745 (20%), Positives = 276/745 (37%), Gaps = 72/745 (9%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++LEC + A P P+I W +G + D + E L++ + G Y+ Sbjct: 3465 LVLECSVEADPAPEIEWHREGVLLQADAHTQFPEEGRF------LQLQALSTADSGDYSC 3518 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A N G SL +++ PP V + ++ +L Q G P+P ++W K Sbjct: 3519 TAHNAAGSTSLAFHVEVH----RPPTVNASVN-------QTTLLPCQADGVPQPLVSWLK 3567 Query: 771 NNKPVKALPTK----SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 + P+ T+ +G + I +P +D G Y A N G + V Sbjct: 3568 DGVPLDPGSTRWVLAREGLREGLRI-QPVLAEDAGHYLCLASNPAGSDRQGRDLQV---- 3622 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN-FDG 885 EPP +T+ L + +P P + W+++ + + + Q + Sbjct: 3623 ---FEPPAIAPGPSNLTLTAYTPASLPCEASGSPKPLVAWWKDGQKLD--FRLQQGAYRL 3677 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 ++ S DS ++CV SN G++ VT+ V + Q + Sbjct: 3678 LPSNALLLEEPSPQDSALFECVVSNGVGEARKLYWVTVHVPPA--IADDQTDFTATIMAP 3735 Query: 946 VILECQTSHT----VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 V+L C ++ VS + + G +R + G G C Sbjct: 3736 VVLTCHSTGVPAPVVSWSKAGTRLGVRGNGYR-VSPSG---ALEIGQALPIHTGRYTCAA 3791 Query: 1002 KDQETSTMLVVKETIPE--FIRKLQDFE-VKEKDVAILEVEINS-ETADVVWERDGEIIK 1057 ++ V T+ ++ L K+ +L E + + W+++G + Sbjct: 3792 RNAAGMAHKHVVLTVQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSV- 3850 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPPEIITRLQ 1114 P N + +L I + S D G Y C+ ++ + +A VV++PP I T L Sbjct: 3851 PAANPGAGTQVLPGGQLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLP 3910 Query: 1115 NQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDA 1173 + + +G A T + V W KDG + + + TI + L + + + DA Sbjct: 3911 DLSITEGAHALLPCTATGSPEPKVTWEKDGQPVSGAKG-KFTIQPSGELL-VKNSESQDA 3968 Query: 1174 GEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI-------PDETLD 1226 G Y+C N+ A V L LP F +P + L ++ T Sbjct: 3969 GTYTCTAENAVGRARRRVHLT----ILALPVFTTLPGDRSLRLGDKLWLHCAARGSPTPQ 4024 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKC-TEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 + W ++ TE +S+ + + R T +D Y C + + V V Sbjct: 4025 IGWTVNNRLVTATEG---VSEQDGGSTLQRVAVTREDSGTYVCWAENRVGRVQAVSFVHV 4081 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P ++ ++ G V L P P EW+ + ++ + + D S Sbjct: 4082 KGVPVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRLQTLPDG---S 4138 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHA 1369 L +++VE DAG Y+ N G A Sbjct: 4139 LWLERVEARDAGPYECVAHNLLGSA 4163 Score = 75.4 bits (177), Expect = 2e-11 Identities = 126/618 (20%), Positives = 228/618 (36%), Gaps = 45/618 (7%) Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEI 1128 R L I + D G Y C+ + + E+ V PP I+ QN V E Sbjct: 1823 RVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNAPPSILGEEQNVSVVANESVALEC 1882 Query: 1129 EL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNS 1183 ++ W KDG ++ + L+ D K L++ ++ D G Y+CE VG S Sbjct: 1883 RSHAVPPPVLSWRKDGRPLEPRPGVYLSAD--KALLEVDRAEVGDTGRYTCEALNQVGRS 1940 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 + L V P + F R P + V A L+ + +KK E + Sbjct: 1941 EKHYNLNVWVPPV-FPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPLPGEGVS 1999 Query: 1244 LIS-DVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREY---R 1298 L R L + + + YTC + A ++++ + VV PP+I Y Sbjct: 2000 LAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVPPRIAGPLEPYADVS 2059 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + + + +L + P P W + + + + + SL +++ + AG Y Sbjct: 2060 VVQDEEASLECNATGKPAPRVTWERDGWPVG--PESGLRLQNHGQSLHVERAQPAHAGRY 2117 Query: 1359 KLRLENNCGHADVEMNVTIL-DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 EN G A+ ++++L + P P G E ++ C + G+ ++ Sbjct: 2118 SCVAENEAGRAERRFSLSVLGEDPQPSGGGQ--EAARQPLSPC-----SWGHLLVLPGAR 2170 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + S ++ ++ Q +Q L + S +Y + + + ET Y V E Sbjct: 2171 PLANAALSG--SCEHCSQNQDRLQIALISLPSPHLNSYCIPQGGGEEWEETRREYLVPPE 2228 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY------E 1530 PL N+T + + L C G+P P + W+R + + + TY Sbjct: 2229 LIGDL----GPLTNVTATLHSPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKI 2284 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKVGDE 1589 + Y C+A N+ GE V + P + I Sbjct: 2285 SGWMLKLTRAQEQDRGLYSCLASNEAGEARRDFSVEVLGTSPRGSHGRPPILPSSLRASG 2344 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + G P P+V W+K+G L + ++++ +++ + S + Y A+N Sbjct: 2345 ---SGPSTGHPQPKVTWFKDGQPLASGDAHHVS--PDGALLWVLHANLSSAGHYACVAAN 2399 Query: 1650 TAGTSSVEVTLKVYDKPS 1667 G + L V P+ Sbjct: 2400 AIGEKTKHFQLSVLVVPT 2417 Score = 72.1 bits (169), Expect = 2e-10 Identities = 60/203 (29%), Positives = 92/203 (45%), Gaps = 20/203 (9%) Query: 632 IPPTF-SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 +PP F S++P+ V EG L C +P P I+W G+ + P E +S+A S + Sbjct: 1950 VPPVFPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQPL-PGEGVSLAQVSAVGR 2008 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV---IEPLKSMIVR 747 +L + + QEGTYT N G +S L + PP++ +EP + V Sbjct: 2009 ---LLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYV----PPRIAGPLEPYADVSVV 2061 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804 Q E L G P P +TW ++ PV L ++ G + + +P G Y+ Sbjct: 2062 QDEEASLECNATGKPAPRVTWERDGWPVGPESGLRLQNHGQSLHVERAQPAHA---GRYS 2118 Query: 805 LKAENSEGIAETSAVITV--EEP 825 AEN G AE ++V E+P Sbjct: 2119 CVAENEAGRAERRFSLSVLGEDP 2141 Score = 69.3 bits (162), Expect = 1e-09 Identities = 68/338 (20%), Positives = 137/338 (40%), Gaps = 24/338 (7%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNI-LEIDSSS 1396 +S ++S I + + G Y+ + G + + + P PN+ + ++ Sbjct: 446 ESGNSSWEIPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVPNVTVSPGETA 505 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 I C E N T +V +++ + + V + ++N + R++ A Sbjct: 506 ILSCLVLSEAPYNLT---WVRDWRVLSASTG-RVTQLADLSLEVRNTTPSDGGRYQCMAS 561 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N ++ AS + +++E +P V ++ ++ + C G P P ++W Sbjct: 562 NSNGVTRAS----VWLLVRE----APQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWS 613 Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 R+G+ L+ ++ + + Y C A N+ G E + + P ++ Sbjct: 614 REGRALQEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSA 673 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634 N + G+E ++ G+PPP VIWY+ D E + ++ S ++RI Sbjct: 674 VNGVVLAAK--GEEAVLECEATGVPPPRVIWYR------GDLEMILAPEDSISGMLRIPV 725 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++ + YT A N G +S E+ L+V P E P Sbjct: 726 VRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELP 763 Score = 66.5 bits (155), Expect = 8e-09 Identities = 127/577 (22%), Positives = 212/577 (36%), Gaps = 65/577 (11%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILT--VE-- 1192 + W KDG + N+IQL + G L+I + +DAG+Y+C V N A+ VE Sbjct: 2452 ITWMKDGVPFEALNNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVL 2509 Query: 1193 -EPSINFTLRLPEFIL--VPANTDAYLTVE-----IPDETLDVTWYKK-----KSVIEDT 1239 PSI+ E + V ++ LT+E +P T ++WYK + + Sbjct: 2510 IPPSISKDDLFGEVSMKEVKTKVNSTLTLECESWAVPPPT--ISWYKDGQNLPEKPVTPN 2567 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYER-- 1295 ++ ++ + R L I+ D Y CV + + V + +F E Sbjct: 2568 QRVRILGE--GRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQDFETPFWGEEARG 2625 Query: 1296 ---EYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 EYR I + L D A P W + + S+ L I V Sbjct: 2626 GVTEYREIVENNPAYLYCDTNAVPAAELTWYRGDRPLSI--EDGVSVLQGGRVLQIPLVR 2683 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 DAG Y + N G + + +L P G+ L ++ ++N NST Sbjct: 2684 AEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGETEEL-VEEVTVN---------ANST 2733 Query: 1412 I-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD--ISDASETT 1468 + ++ V T W+ +Q L+ + V + + A Sbjct: 2734 VSLHCPVLGNPAPTISWLQNGLPFSPSPRLQVLENGRILQVSTAEVADAASYMCVAENPA 2793 Query: 1469 EYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 + + ++Q P + IT N + L C P P+VTWY+DG L + Sbjct: 2794 GSTEKLFTLRVQGEPGLNP-EQITATLNSSVSLPCDVRAHPSPEVTWYKDGWTLSLGEEI 2852 Query: 1529 Y--ENRXXXXXXXXXXXXXXXYKCIAFN----DHGEVETSCVV-GIQQKPVITISNEDIK 1581 + Y C A N DH V+ S + G +P +D+ Sbjct: 2853 FLLPGTHTLQLTRVQLLDSGMYICEALNAAGRDHKLVQLSVLAPGAPSRP------QDVV 2906 Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 GD+ +++ + P P V W K+G L + + + I++ + S Sbjct: 2907 LV-SAGDKAVLSCETDAFPEPTVAWQKDGQPLVLPERIQALLGGQR--LEIQDAQVSDKG 2963 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPS--KPEGPVIMR 1676 Y+ SN AG + +L V P+ PE ++ R Sbjct: 2964 LYSCRVSNAAGEAMRAFSLTVQVPPTFENPETEMVSR 3000 Score = 55.2 bits (127), Expect = 2e-05 Identities = 43/193 (22%), Positives = 72/193 (37%), Gaps = 9/193 (4%) Query: 1479 IQSPTVEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR----X 1533 +Q+ V KPL ++ E++ L C G+P+P + W ++G + A + Sbjct: 3806 VQASPVVKPLPSVVWAVAKEEVLLPCEASGIPRPSIAWQKEGLSVPAANPGAGTQVLPGG 3865 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y C+A N G + +Q P I D+ G L+ Sbjct: 3866 QLRIIHVSPEDAGNYFCLAQNSAGSAVRKTRLVVQVPPAIKTGLPDLSITE--GAHALLP 3923 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 G P P+V W K+G + K T + + + +K + + YT A N G Sbjct: 3924 CTATGSPEPKVTWEKDGQPVSGAK--GKFTIQPSGELLVKNSESQDAGTYTCTAENAVGR 3981 Query: 1654 SSVEVTLKVYDKP 1666 + V L + P Sbjct: 3982 ARRRVHLTILALP 3994 Score = 54.0 bits (124), Expect = 4e-05 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576 R + G V+ C GYP P I+W R+ ++ ++ D TL+I+ V PE Sbjct: 586 RSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRV----DAQGTLIIQGVAPE 641 Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLS 605 DAG+++C A N G T L P S Sbjct: 642 DAGSYSCQAANEIGRDEETVTLYYTDPPS 670 Score = 51.2 bits (117), Expect = 3e-04 Identities = 42/181 (23%), Positives = 77/181 (42%), Gaps = 11/181 (6%) Query: 1507 GVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G PQPKVTW++DG+ L + A + + Y C+A N GE Sbjct: 2350 GHPQPKVTWFKDGQPLASGDAHHVSPDGALLWVLHANLSSAGHYACVAANAIGEKTKHFQ 2409 Query: 1565 VGIQQKP-VITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNI 1621 + + P ++ ++ + + ++ V ++ + E P P + W K+G E NI Sbjct: 2410 LSVLVVPTILGVTEDSMDEEVTVTINNPISLICETRAFPTPTITWMKDGVPFE--ALNNI 2467 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE----GPVIMRE 1677 T ++I ++ + +YT +N G + ++V PS + G V M+E Sbjct: 2468 QLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAMKNYHVEVLIPPSISKDDLFGEVSMKE 2527 Query: 1678 I 1678 + Sbjct: 2528 V 2528 Score = 47.6 bits (108), Expect = 0.004 Identities = 51/244 (20%), Positives = 89/244 (36%), Gaps = 12/244 (4%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 IQ + + + A NE+ D T YY P+V + E+ Sbjct: 635 IQGVAPEDAGSYSCQAANEIG-RDEETVTLYYT-------DPPSVSAVNGVVLAAKGEEA 686 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 L C GVP P+V WYR ++ A + Y C A N+ G+ Sbjct: 687 VLECEATGVPPPRVIWYRGDLEMILAPEDSIS-GMLRIPVVRERDAGVYTCRAVNELGDA 745 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 + + P + +D+ + +G L+ G P P + W++ ++ + Sbjct: 746 SAEIRLEVGHAPQLLELPQDVTVE--LGRSALLACRATGHPLPTITWHRGDDQPLGLRGS 803 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 + + S + + + + +Y+ SNTAG+ +V L V K P I+ Sbjct: 804 RHSIRADGS-LHLDQALLEDAGRYSCVVSNTAGSHHRDVQLVVQVKVPPRIQPTATHHIT 862 Query: 1680 RESV 1683 E V Sbjct: 863 NEGV 866 Score = 47.2 bits (107), Expect = 0.005 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 4/84 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F K + G +V CQ G P P + W R ++ SQ Q D +L Sbjct: 4085 PVFQVKPQDVTVRSGDSVALRCQASGEPAPTMEWLRAGQPVRASQRLQTLPD----GSLW 4140 Query: 570 IREVFPEDAGTFTCVAKNAAGFAS 593 + V DAG + CVA N G A+ Sbjct: 4141 LERVEARDAGPYECVAHNLLGSAT 4164 Score = 41.9 bits (94), Expect = 0.19 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 3/80 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G+ C G P P++TW + +P + + L+++ +DAGT+T Sbjct: 3916 EGAHALLPCTATGSPEPKVTWEKDG---QPVSGAKGKFTIQPSGELLVKNSESQDAGTYT 3972 Query: 583 CVAKNAAGFASSTTELIVEA 602 C A+NA G A L + A Sbjct: 3973 CTAENAVGRARRRVHLTILA 3992 Score = 41.5 bits (93), Expect = 0.25 Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 EC G P P++TW R + P ++ ++ +L + P AG ++CVA+N A Sbjct: 2069 ECNATGKPAPRVTWERDGWPVGPESGLRL---QNHGQSLHVERAQPAHAGRYSCVAENEA 2125 Query: 590 GFASSTTELIV 600 G A L V Sbjct: 2126 GRAERRFSLSV 2136 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 2/115 (1%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKL-RPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 E ++++ EK + + P+F + R +G + C G P P+I+W + Sbjct: 1932 EALNQVGRSEKHYNLNVWVPPVFPSREPRTLTVTEGHPARLSCDCRGVPFPKISWKKDGQ 1991 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + P + + L + P GT+TC N AG +S +L+V P Sbjct: 1992 PL-PGEGVSLAQVSAVGRLLYLGRAQPAQEGTYTCECSNVAGNSSQDQQLVVYVP 2045 Score = 39.5 bits (88), Expect = 0.99 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 5/100 (5%) Query: 503 SEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 S E +AP + E L T G ++ C G P P I W + P+++ + Sbjct: 1506 SVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNG---HPAEELPGVH 1562 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 TL I V AG F C A N AG A++ EL V Sbjct: 1563 VTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSV 1602 Score = 39.5 bits (88), Expect = 0.99 Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTC 583 S + C+ G P P I WFR + P ++ + + + L + +D G ++C Sbjct: 2245 SPLSLFCEATGIPPPGIRWFRGEEPVSPGENTYLLAGKKISGWMLKLTRAQEQDRGLYSC 2304 Query: 584 VAKNAAGFA--SSTTELIVEAPLSDHG 608 +A N AG A + E++ +P HG Sbjct: 2305 LASNEAGEARRDFSVEVLGTSPRGSHG 2331 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 9/103 (8%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 EK +L V+ PT E P V+ + G + EC GYP P ++W+ + Sbjct: 1408 EKTTRLEVYVPPTIEGTGEGPRVVKAVA------GRPLTLECVARGYPPPTVSWYHEGL- 1460 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 P D + L + + G ++CVA + AG A Sbjct: 1461 --PVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 1501 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 3/81 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F + G + C G P PQI W ++ ++ + D +TL Sbjct: 3994 PVFTTLPGDRSLRLGDKLWLHCAARGSPTPQIGWTVNNRLVTATEGVS---EQDGGSTLQ 4050 Query: 570 IREVFPEDAGTFTCVAKNAAG 590 V ED+GT+ C A+N G Sbjct: 4051 RVAVTREDSGTYVCWAENRVG 4071 Score = 37.5 bits (83), Expect = 4.0 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 10/79 (12%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-DDDNVATLV-IREVFPEDAGTF 581 G EC+ G P P++ W+R D +M +D+++ ++ I V DAG + Sbjct: 683 GEEAVLECEATGVPPPRVIWYR--------GDLEMILAPEDSISGMLRIPVVRERDAGVY 734 Query: 582 TCVAKNAAGFASSTTELIV 600 TC A N G AS+ L V Sbjct: 735 TCRAVNELGDASAEIRLEV 753 Score = 36.3 bits (80), Expect = 9.2 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I+WF+ I + D M D V L+I + DAG++ CVA N G L V Sbjct: 1801 ISWFKGRQPIS-AWDRAMVSTDGRV--LLIEQAQLSDAGSYRCVASNVVGSTELQYSLRV 1857 Query: 601 EAPLSDHGSEMTV 613 AP S G E V Sbjct: 1858 NAPPSILGEEQNV 1870 >UniRef50_A7RGM1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 551 Score = 148 bits (359), Expect = 1e-33 Identities = 157/613 (25%), Positives = 263/613 (42%), Gaps = 94/613 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F++ ++P +G T FEC V+GYPRP I WF+ +K ++ Y + +++L Sbjct: 1 PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTY-EGALSSLT 59 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I + +D G + CVA+N+ G AS TEL+ +G+ Sbjct: 60 INQCTIDDEGNYKCVARNSFGKASCATELLTNL----NGTHTHPPHF------------- 102 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 I F P A+ +EG D+ LE R+ P+P + WL E I+ + V+ +D+H Sbjct: 103 --IDKHFETAP-AEVTEEG-DVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVH 158 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 L I + + G Y V+A N G AS + + E +P +E LK Sbjct: 159 ----TLVINSPNQDDIGQYKVIASNHRGMASRTFDVNV---EGKPKPSVEWLK------- 204 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + RP + ++ +K T+ D D +S+TI +P K DEG+YT+K N Sbjct: 205 -----------DDRPVL----SDSHIKM--TEED-DIYSLTIREPTK-SDEGMYTVKITN 245 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G + + VE+ T ++ P E T E+G ++L ++T PVP ++W ++ Sbjct: 246 DVGSGTRTFDVKVEDTTTNDSFVPF------EST--EEGNVRLSVKITGKPVPEVSWTKD 297 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE-KV 928 + + + I + + L I DSG YKC +N AGKS+ V I+ E K Sbjct: 298 EKPVHKIQNIRLDHQDDIYTLTIREATPN-DSGSYKCTLTNDAGKSTRTFSVEIEGETKP 356 Query: 929 TFVKHLQKSYE--TEEGKTVILECQTSHTV--------STKWYHNKKEISGMDHREIIQE 978 K ++ + EE V E + T S +W+ + +S +H I +E Sbjct: 357 EKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITEE 416 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQ------------ETSTMLVVKETI-PEFIR--KL 1023 D G V ++ + + + K+ + P+FI Sbjct: 417 DGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSF 476 Query: 1024 QDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSV 1081 F+ ++ L V++ + +V W +DG+ + N + D ++ +I L IR S Sbjct: 477 VPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRYI--LTIREASP 534 Query: 1082 HDEGEYSCILRDE 1094 D G Y C L + Sbjct: 535 DDSGSYRCTLTSD 547 Score = 119 bits (287), Expect = 8e-25 Identities = 147/577 (25%), Positives = 236/577 (40%), Gaps = 74/577 (12%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITI 791 PQ I+ ++ + V +G++ V G PRP+I W KN P+K + + +G S+TI Sbjct: 1 PQFIDLMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTI 60 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEIT---VKEKG 848 + DEG Y A NS G A + A + + PP FI++ E V E+G Sbjct: 61 -NQCTIDDEGNYKCVARNSFGKA-SCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEG 118 Query: 849 TIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 ++L RV +P PS+ W +++E+I SP ++ + D + ++ N ++ D G YK Sbjct: 119 DVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHAD---VHTLVINSPNQDDIGQYKV 175 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKE 966 +ASN G +S T DV EGK S +W + + Sbjct: 176 IASNHRGMASR----TFDV--------------NVEGKP---------KPSVEWLKDDRP 208 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTMLV-VKETIPEFIRKLQ 1024 + H ++ +E D G+ I D + T VK Sbjct: 209 VLSDSHIKMTEEDDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFV 268 Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 FE E+ L V+I + +V W +D + + +N + + I L IR + +D Sbjct: 269 PFESTEEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQN-IRLDHQDDIYTLTIREATPND 327 Query: 1084 EGEYSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGN---------KATFEIELT-- 1131 G Y C L +++ + T VE+ E +G A E+E+T Sbjct: 328 SGSYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQ 387 Query: 1132 ---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN----SK 1184 K V WFKD + HI +T + L I + D G Y+ EV N + Sbjct: 388 VTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGR 447 Query: 1185 CTAILTVEE--PSINFTLRLPEFI----LVPANT----DAYLTVEIPDE-TLDVTWYKKK 1233 T ++V++ +I P+FI VP + D LTV++ + +VTW K Sbjct: 448 RTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDG 507 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 ++ L + L IR+ + DD Y C L Sbjct: 508 KPVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTL 544 Score = 101 bits (242), Expect = 2e-19 Identities = 74/286 (25%), Positives = 137/286 (47%), Gaps = 25/286 (8%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 E ++ L ++ P P+++W + + +NI + + D++ L I G Sbjct: 274 EEGNVRLSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIY----TLTIREATPNDSG 329 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEP----PQVIE--PLKS--MIVRQGESVILSAQV 758 +Y N G+++ ++I+ GE +P P E PL+ + V V ++AQV Sbjct: 330 SYKCTLTNDAGKSTRTFSVEIE-GETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQV 388 Query: 759 VGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 G P+P++ W K++ PV T+ DG T+S+ I +P K KDEG YT++ N G+ Sbjct: 389 TGKPQPSVEWFKDDVPVSPDEHITITEEDG-TYSLVIKEPTK-KDEGTYTVEVSNEAGLG 446 Query: 815 ETSAVITVEEPTE---ENAEPPLFIN--RFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 + ++V++ + ++A P FI F ++G ++L +VT P P +TW ++ Sbjct: 447 RRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKD 506 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 + + + + + L I + DSG Y+C ++ GKS Sbjct: 507 GKPVDKLPNVELDHQEDRYILTIREASPD-DSGSYRCTLTSDVGKS 551 Score = 89.4 bits (212), Expect = 9e-16 Identities = 104/512 (20%), Positives = 195/512 (38%), Gaps = 61/512 (11%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE- 1285 + W+K +++ E+ + +L I +CT DD+ Y CV ++ E++ Sbjct: 32 IEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGKASCATELLTN 91 Query: 1286 ------FPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 PP +D E + DV L V P+P+ +W+ + ++I H Sbjct: 92 LNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDEVIISSPHFMV 151 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 S + +L I D G YK+ N+ G A +V + KP KP++ + Sbjct: 152 SSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGKP----KPSVEWLKD-- 205 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 D P + + ++ E D ++++ TK+ + +K + Sbjct: 206 -----DRPVLSDSH------IKMTEEDDIYSLTIREPTKSDEGMYTVKITN--------- 245 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 D+ + T + K++ T + ++ L+ G P P+V+W Sbjct: 246 ---DVGSGTRTFD-------VKVEDTTTNDSFVPFESTEEGNVRLSVKITGKPVPEVSWT 295 Query: 1517 RDGK---KLKTAKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +D K K++ + +++ YKC ND G+ + V I+ + Sbjct: 296 KDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDAGKSTRTFSVEIEGETK 355 Query: 1573 ITISNEDIKQKHKVGDEWL---------VTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 ++ + +E L +TA + G P P V W+K+ + D+ IT Sbjct: 356 PEKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWFKDDVPVSPDEHITITE 415 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 ++ T + IKE + YT+E SN AG + V D + + + Sbjct: 416 EDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGS 475 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 + ++ D+G + LT K EP+ W K Sbjct: 476 FVPFQ-STDEGDVRLTVKVTGKPEPEVT-WTK 505 Score = 86.2 bits (204), Expect = 9e-15 Identities = 75/314 (23%), Positives = 127/314 (40%), Gaps = 44/314 (14%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 DE YT + + V + T+ S P + T +G+ V+ ++ G Sbjct: 235 DEGMYTVKITNDVGSGTRTFDVKVEDTTTNDSFVPF-------ESTEEGN-VRLSVKITG 286 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 P P+++W + + Q+ ++ + DD + TL IRE P D+G++ C N AG ++ T Sbjct: 287 KPVPEVSWTKDEKPVHKIQNIRLDHQDD-IYTLTIREATPNDSGSYKCTLTNDAGKSTRT 345 Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 + +E + T EG P + P V +++ + Sbjct: 346 FSVEIEGETKPEKGKPTER---------------EGKPLEEEELP----VSAETEVEMTA 386 Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 ++ P+P + W + PDE+I++ E + L I K EGTYTV N Sbjct: 387 QVTGKPQPSVEWFKDDVPVSPDEHITITEEDGTYS----LVIKEPTKKDEGTYTVEVSNE 442 Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----------SVILSAQVVGNPRPT 765 G + + K P+ + +K + G V L+ +V G P P Sbjct: 443 AGLGRRTFDVSVDDTRKTIPK--DAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPE 500 Query: 766 ITWCKNNKPVKALP 779 +TW K+ KPV LP Sbjct: 501 VTWTKDGKPVDKLP 514 Score = 74.5 bits (175), Expect = 3e-11 Identities = 110/493 (22%), Positives = 179/493 (36%), Gaps = 61/493 (12%) Query: 934 LQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 L + E EG+T EC S +W+ N + + EG Sbjct: 6 LMQPVEVTEGQTATFECTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTI 65 Query: 992 XDVGVIKCIVKDQ--------ETSTMLVVKETIP-EFIRK---LQDFEVKEKDVAILEVE 1039 D G KC+ ++ E T L T P FI K EV E+ LEV Sbjct: 66 DDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVR 125 Query: 1040 INSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA 1098 + V W +D E+I + + + L I + + D G+Y I + A Sbjct: 126 VGGHPKPSVQWLKDDEVIISSPH-FMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMA 184 Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTID 1157 TF++ + K V W KD + +HI++T + Sbjct: 185 S------------------------RTFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEE 220 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY-- 1215 L I + D G Y+ ++ N + T + + T F+ + + Sbjct: 221 DDIYSLTIREPTKSDEGMYTVKITNDVGSGTRTFDV-KVEDTTTNDSFVPFESTEEGNVR 279 Query: 1216 LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272 L+V+I + + +V+W K + + + L TL IR+ T +D Y C L + Sbjct: 280 LSVKITGKPVPEVSWTKDEKPVHKIQNIRLDHQDDIYTLTIREATPNDSGSYKCTLTNDA 339 Query: 1273 AKSTTKLKVEVV--EFPPKIVDYEREYR--------IKRGSDVTLLVDYQAFPQPNDEWI 1322 KST VE+ P K ERE + + ++V + PQP+ EW Sbjct: 340 GKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQVTGKPQPSVEWF 399 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA----DVEMNVTIL 1378 + + +H + + + SL IK+ D G Y + + N G DV ++ T Sbjct: 400 KDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRTFDVSVDDTRK 459 Query: 1379 DKPSPPGKPNILE 1391 P KP +E Sbjct: 460 TIPKDAVKPKFIE 472 Score = 74.1 bits (174), Expect = 4e-11 Identities = 132/583 (22%), Positives = 217/583 (37%), Gaps = 67/583 (11%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P+ I +Q +V +G ATFE + KG + WFK+G ++ + I T +G L Sbjct: 1 PQFIDLMQPVEVTEGQTATFECTV-KGYPRPSIEWFKNGLPLKENERIASTYEGALSSLT 59 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVE-EPSINFT-LRLPEFI-----LVPANT----D 1213 I C +DD G Y C NS A E ++N T P FI PA D Sbjct: 60 INQCTIDDEGNYKCVARNSFGKASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGD 119 Query: 1214 AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 L V + V W K VI + F + S TL+I +DD +Y + + Sbjct: 120 VRLEVRVGGHPKPSVQWLKDDEVIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASN 179 Query: 1273 AKSTTKLKVEV-VEFPPK-IVDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + +V VE PK V++ ++ R + S + + + + E + + + Sbjct: 180 HRGMASRTFDVNVEGKPKPSVEWLKDDRPVLSDSHIKMTEEDDIYSLTIREPTKSDEGMY 239 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 K T + S + + + KVE+T + E+ +V ++V I KP P Sbjct: 240 TVKITN-DVGSGTRTFDV-KVEDTTTNDSFVPFEST-EEGNVRLSVKITGKPVP------ 290 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 + W + E V + Q I + +T I+ N S Sbjct: 291 --------EVSWTKDEKP--------VHKIQNIRLDHQDDIYTLT-----IREATPNDSG 329 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE-KPL--KNITTEPNEDIELTCIFG 1506 ++ N+ S + + E K K + E KPL + + ++E+T Sbjct: 330 SYKCTLTNDAGKSTRTFSVEIEGETKPEKGKPTEREGKPLEEEELPVSAETEVEMTAQVT 389 Query: 1507 GVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGEVETS 1562 G PQP V W++D + + T E+ Y N+ G + Sbjct: 390 GKPQPSVEWFKDDVPVSPDEHITITEEDGTYSLVIKEPTKKDEGTYTVEVSNEAGLGRRT 449 Query: 1563 CVVGIQQKPVITISNEDIKQK---------HKVGDEWLV--TAVIEGIPPPEVIWYKNGN 1611 V + TI + +K K + DE V T + G P PEV W K+G Sbjct: 450 FDVSVDDTRK-TIPKDAVKPKFIEDGSFVPFQSTDEGDVRLTVKVTGKPEPEVTWTKDGK 508 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 ++ + +E ++ I+E S Y ++ G S Sbjct: 509 PVDKLPNVELDHQEDRYILTIREASPDDSGSYRCTLTSDVGKS 551 Score = 46.8 bits (106), Expect = 0.007 Identities = 41/178 (23%), Positives = 68/178 (38%), Gaps = 12/178 (6%) Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAK---ATYENRXXXXXXXX-XXXXXXXYKCIAFNDHGE 1558 C G P+P + W+++G LK + +TYE YKC+A N G+ Sbjct: 22 CTVKGYPRPSIEWFKNGLPLKENERIASTYEGALSSLTINQCTIDDEGNYKCVARNSFGK 81 Query: 1559 VETSCVV-----GIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611 + + G P I +V +E V + G P P V W K+ Sbjct: 82 ASCATELLTNLNGTHTHPPHFIDKHFETAPAEVTEEGDVRLEVRVGGHPKPSVQWLKDDE 141 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + + + +++ + I + +Y + ASN G +S + V KP KP Sbjct: 142 VIISSPHFMVSSHADVHTLVINSPNQDDIGQYKVIASNHRGMASRTFDVNVEGKP-KP 198 Score = 46.0 bits (104), Expect = 0.011 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 6/120 (5%) Query: 476 DENNYTQYLQKK--LNEKIDKLPVFE-KPTSEEQSMAPIFVE--KLRPKHTPDGSTVQFE 530 DE YT + + L + + V + + T + ++ P F+E P + D V+ Sbjct: 431 DEGTYTVEVSNEAGLGRRTFDVSVDDTRKTIPKDAVKPKFIEDGSFVPFQSTDEGDVRLT 490 Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +V G P P++TW + + + ++ + +D L IRE P+D+G++ C + G Sbjct: 491 VKVTGKPEPEVTWTKDGKPVDKLPNVELDHQEDRY-ILTIREASPDDSGSYRCTLTSDVG 549 >UniRef50_UPI00005A1317 Cluster: PREDICTED: similar to eEF1A2 binding protein; n=3; Canis lupus familiaris|Rep: PREDICTED: similar to eEF1A2 binding protein - Canis familiaris Length = 1264 Score = 147 bits (355), Expect = 4e-33 Identities = 90/379 (23%), Positives = 165/379 (43%), Gaps = 9/379 (2%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G V + P + W K+G ++ + + + + + + + R + Sbjct: 562 KAGKPVTVKIPFQSHLPVQAAWKKDGVEVAGGSGRGPQVALGDGFTRLCLPSAGRKDGGQ 621 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y++ S+ G++ EVTL+V DKP P+GP+ +++ V + W+PP DDGG L +Y Sbjct: 622 YSVTLSSEGGSARAEVTLQVIDKPQPPQGPLEVQDRHGAGVCLHWRPPRDDGGQALERYV 681 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIK 1761 +E+ + + W+KV + D T+ + + +Y FRV A G EALES E +V Sbjct: 682 VERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAEVLVAP 741 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXX 1820 AL P ++ + +TW G + I+ Y +E +++G W Sbjct: 742 EALPRPPSAPAIQAA---SSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWTAVNAQP 798 Query: 1821 XXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 R + + Y+FR+ A + G P D + + P R V++++ Sbjct: 799 VPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVRELQVTDTS 858 Query: 1879 SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 S+TL W P++ G Y++E + G W+ ++ ++ ++ Sbjct: 859 HTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLRPQEGYFV 918 Query: 1939 RISAENTVGVSLPTESQSV 1957 R++A N G PT +V Sbjct: 919 RVTAVNDGGRGQPTALDTV 937 Score = 89.8 bits (213), Expect = 7e-16 Identities = 90/430 (20%), Positives = 164/430 (38%), Gaps = 21/430 (4%) Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 S EV + P P P I + S + +T+ W P G + Y IEK + +N W Sbjct: 734 SAEVLVAPEALPRPPSAPAI-QAASSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWT 792 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXX 1773 V + + + + C+Y FRV A +P G E S+ + + + VP Sbjct: 793 AVNAQPVPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVREL 852 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXXXARIQKLS 1830 + S+ ++W P + G Y VE++ +G +W ++ L Sbjct: 853 QVTDT-SHTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLR 911 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-- 1888 Y R+ A N+ G P D T+ + + +P+ F++ T S ++ + Sbjct: 912 PQEGYFVRVTAVNDGGRGQPTALD---TVVQAMPVTVRPK-FLMDSGTKDSRMVRAGDTV 967 Query: 1889 --PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946 P S +PI + K + + + + I D ++ + + Sbjct: 968 RVPISFEAAPIPE-VTWLKDGLPLPKRNVTSTKEGLTQLLIPAASLSDSGLYTVVLRSLQ 1026 Query: 1947 GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 G T S+R+ A P P P+ ++ V W + G L Y + +R Sbjct: 1027 GEEA-TYRFSLRV---AACPRAP-GPIRLQENVPGTVTAEWEASPDEAGEDPLYYEVLMR 1081 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 + W + V+T + + H Y R+ A+NE+G S P ++ EP+++ Sbjct: 1082 SSARGRWQQAAD-RVHTNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEPWRIPRHRD 1140 Query: 2067 SHADEEPGEQ 2076 + PG + Sbjct: 1141 KFTVKAPGHR 1150 Score = 88.2 bits (209), Expect = 2e-15 Identities = 65/285 (22%), Positives = 109/285 (38%), Gaps = 9/285 (3%) Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSINT--TYQFRIY 1840 V + W P +GG + Y VE +Q G+ W + Y FR+ Sbjct: 662 VCLHWRPPRDDGGQALERYVVERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVR 721 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A G S + + + L PPS P + ++S+ +TL WT P G + I Sbjct: 722 AVTSEGAGEALESAEVLVAPEALPRPPSAP---AIQAASSQGITLTWTAPRGPGSAHILG 778 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TESQSVR 1958 Y+IE + +WT + + ++++ + FR++A + G P S +V Sbjct: 779 YLIEKRKKGSNTWTAVNAQPVPERRWTVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVF 838 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 VP P L++ + SW P+ G GY + +R W Sbjct: 839 ARDPMRVPGP-VRELQVTDTSHTSITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHP 897 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 V F ++ L Y +R+ A N+ G +P D + +P Sbjct: 898 GTVPATTFTVKGLRPQEGYFVRVTAVNDGGRGQPTALDTVVQAMP 942 Score = 85.8 bits (203), Expect = 1e-14 Identities = 92/396 (23%), Positives = 155/396 (39%), Gaps = 27/396 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438 P PP P I S I + W P G++ I+ Y++E ++ + W +V + + + + Sbjct: 745 PRPPSAPAIQAASSQGITLTWTAPRGPGSAHILGYLIEKRKKGSNTWTAVNAQPVPERRW 804 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 ++ +++ Y FR AV+ + ++ ++ P E +T + Sbjct: 805 TVTDVRQGCQYEFRVTAVSPAGPGEPGPPSDAVFARDPMRVPGPVREL---QVTDTSHTS 861 Query: 1499 IELTCI-----FGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXY--KCI 1551 I L+ G Q V R L+ + Y + Sbjct: 862 ITLSWAPPDAQDGDAAQGYVVELRGSDGLQWSPCHPGTVPATTFTVKGLRPQEGYFVRVT 921 Query: 1552 AFNDHGEVETSCVVGIQQKPVITI-------SNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 A ND G + + + + Q +T+ S + + GD V E P PEV Sbjct: 922 AVNDGGRGQPTALDTVVQAMPVTVRPKFLMDSGTKDSRMVRAGDTVRVPISFEAAPIPEV 981 Query: 1605 IWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV-EVTLKV 1662 W K+G L + N+T TKE + + I S S YT+ + G + +L+V Sbjct: 982 TWLKDGLPLP---KRNVTSTKEGLTQLLIPAASLSDSGLYTVVLRSLQGEEATYRFSLRV 1038 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 P P GP+ ++E +VT EW+ D+ G + Y + RW + AD Sbjct: 1039 AACPRAP-GPIRLQENVPGTVTAEWEASPDEAGEDPLYYEVLMRSSARGRWQQAAD-RVH 1096 Query: 1723 VETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEP 1757 Y + EY FRV+A+N +G S + SEP Sbjct: 1097 TNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEP 1132 Score = 60.9 bits (141), Expect = 4e-07 Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 9/178 (5%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTDAG 1356 +K G VT+ + +Q+ W + + P + L + D G Sbjct: 561 VKAGKPVTVKIPFQSHLPVQAAWKKDGVEVAGGSGRGPQVALGDGFTRLCLPSAGRKDGG 620 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINIC--WDEPENTGNSTII 1413 Y + L + G A E+ + ++DKP PP P LE+ D +C W P + G + Sbjct: 621 QYSVTLSSEGGSARAEVTLQVIDKPQPPQGP--LEVQDRHGAGVCLHWRPPRDDGGQALE 678 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469 YVVE ++ + W+ V T+ +++ Y FR AV +A E+ E Sbjct: 679 RYVVERRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAE 736 Score = 58.0 bits (134), Expect = 3e-06 Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S P F+ LR P G C V+G+PRP +TWF+ + D V Sbjct: 1155 SQKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSL-AGHPTAYSTDVLGVC 1213 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +LVI V D G + VA+NA G A ST LIV Sbjct: 1214 SLVIPSVSLRDGGQYKAVAENALGQAVSTATLIV 1247 Score = 55.6 bits (128), Expect = 1e-05 Identities = 35/113 (30%), Positives = 50/113 (44%), Gaps = 3/113 (2%) Query: 1948 VSLPTESQSVRLEKHATV---PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 V+L +E S R E V P PP PLE++ V W P DGG L Y + Sbjct: 624 VTLSSEGGSARAEVTLQVIDKPQPPQGPLEVQDRHGAGVCLHWRPPRDDGGQALERYVVE 683 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 R ++ W++VG+ ++ F + + Y R+ A G E LES E Sbjct: 684 RRQAGRSTWLKVGEPPADSTTFTDTHVEQGKKYTFRVRAVTSEGAGEALESAE 736 Score = 55.2 bits (127), Expect = 2e-05 Identities = 52/247 (21%), Positives = 97/247 (39%), Gaps = 18/247 (7%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ G V + + ++A P P W+ + + K T S L I +D+G+Y Sbjct: 961 VRAGDTVRVPISFEAAPIPEVTWLKDGLPLPKRNVT--STKEGLTQLLIPAASLSDSGLY 1018 Query: 1359 KLRLENNCGH-ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + L + G A ++ + P PG + E ++ W+ + +YY V Sbjct: 1019 TVVLRSLQGEEATYRFSLRVAACPRAPGPIRLQENVPGTVTAEWEASPDEAGEDPLYYEV 1078 Query: 1418 EYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV--- 1473 + W + T + + Y FR A NE+ S S+T+E +++ Sbjct: 1079 LMRSSARGRWQQAADRVHTNHYTFLGVLPGHEYHFRVVAKNELGASLPSDTSEPWRIPRH 1138 Query: 1474 -----IKETKIQSPTV-EKP-----LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 +K + P + +KP L+ + ++C G P+P VTW++D + L Sbjct: 1139 RDKFTVKAPGHREPDLSQKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSL 1198 Query: 1523 KTAKATY 1529 Y Sbjct: 1199 AGHPTAY 1205 Score = 50.0 bits (114), Expect = 7e-04 Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 2/101 (1%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--T 790 + P+ + L++ ++ QG +S V G PRP +TW K+++ + PT D + Sbjct: 1156 QKPRFLVGLRTHLLPQGCECCMSCAVQGWPRPHVTWFKDDQSLAGHPTAYSTDVLGVCSL 1215 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 ++ ++D G Y AEN+ G A ++A + V EE E Sbjct: 1216 VIPSVSLRDGGQYKAVAENALGQAVSTATLIVVGREEEEEE 1256 >UniRef50_Q86TC9 Cluster: Myopalladin; n=20; Amniota|Rep: Myopalladin - Homo sapiens (Human) Length = 1320 Score = 147 bits (355), Expect = 4e-33 Identities = 98/375 (26%), Positives = 179/375 (47%), Gaps = 17/375 (4%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 Q LM+E + + + ++E D++ E PT + +APIF ++L+ +GS V F C Sbjct: 910 QRLMNEIEF-RLERTPVDESDDEIQHDEIPTGK--CIAPIFDKRLKHFRVTEGSPVTFTC 966 Query: 532 QVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 ++ G P P++ WF+ I K ++ +M + D +L I +D G +T +A N G Sbjct: 967 KIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQG 1026 Query: 591 FASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPKAQYVDE 647 S + L+V++ P+ + + L+ P F + P E Sbjct: 1027 RISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHE 1086 Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEG 706 G L+C++ +P P++ WL G+ ++PD + + + E+ +H L I + + G Sbjct: 1087 GRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHS----LLIDPLTQRDAG 1142 Query: 707 TYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 TY +A N+ G+ S + L + E K+ P ++E L++ V +G V L +V+G P P Sbjct: 1143 TYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPV 1202 Query: 766 ITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 W K+N+ + + + D ++ +++P K D G YTL A+N GI +A + Sbjct: 1203 FYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLD 1262 Query: 822 VEEPTEENAEPPLFI 836 + PP+ + Sbjct: 1263 IYAQWHHQIPPPMSV 1277 Score = 96.3 bits (229), Expect = 8e-18 Identities = 91/329 (27%), Positives = 141/329 (42%), Gaps = 45/329 (13%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHM 690 I P F K+ K V EGS + C++V IP P + W G++I +E+ + E D Sbjct: 943 IAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT- 1001 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEAS---------LPIVLKIKTG----------- 730 CS L I + +G YT++A N +G S LPI ++ + Sbjct: 1002 -CS-LHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQ 1059 Query: 731 --EKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781 +KEP P ++ M+ +G L +V G P P +TW N +PV LP Sbjct: 1060 ERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPV--LPDA 1117 Query: 782 S------DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 S + HS+ ++ P +D G Y A N G + S + + +E + P+ Sbjct: 1118 SHKMLVRETGVHSL-LIDPLTQRDAGTYKCIATNKTG--QNSFSLELSVVAKEVKKAPVI 1174 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITN 894 + + Q V E ++L RV P P W ++NE I E I+ + D ++ Sbjct: 1175 LEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQ 1234 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + D+G Y A N AG S AR+ I Sbjct: 1235 PAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263 Score = 84.2 bits (199), Expect = 4e-14 Identities = 47/142 (33%), Positives = 71/142 (50%), Gaps = 9/142 (6%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------D 561 AP+F + L+ +G V FEC+V+G P P++ W+R+ +I+ S DF++ + Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA--PLSDHGSEMTVXXXXXX 619 + + TLVI EVF ED+G FTC A N G SS +L V LS++GS + Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNL 553 Query: 620 XXXXXXADILEGIPPTFSKKPK 641 PP+ + PK Sbjct: 554 AAIEPQPSPPHSEPPSVEQPPK 575 Score = 72.5 bits (170), Expect = 1e-10 Identities = 37/107 (34%), Positives = 57/107 (53%), Gaps = 2/107 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E P F +KLR + P+G+ VQ +C V G P PQ+ W+ + ++ S D + Sbjct: 263 EPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI-VQAG 321 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610 N+ +L I E F ED G ++C A N G S++ E+ +E +S SE Sbjct: 322 NLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEG-VSSSDSE 367 Score = 68.5 bits (160), Expect = 2e-09 Identities = 58/259 (22%), Positives = 108/259 (41%), Gaps = 33/259 (12%) Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTK 781 +I TG+ P + LK V +G V + ++VG P P + W K+ K + + Sbjct: 936 EIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMR 995 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE------------------ 823 +GD ++ D+G YT+ A N +G S + V+ Sbjct: 996 REGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGR 1055 Query: 824 --------EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 EP +E P F+ ++ E +L +V+ P P +TW N + + P Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLP 1115 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTFVK 932 + + ++ + ++ D+G YKC+A+N G++S +++ +V+K + Sbjct: 1116 DASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVIL 1175 Query: 933 HLQKSYETEEGKTVILECQ 951 ++ EG V LEC+ Sbjct: 1176 EKLQNCGVPEGHPVRLECR 1194 Score = 50.8 bits (116), Expect = 4e-04 Identities = 49/177 (27%), Positives = 75/177 (42%), Gaps = 18/177 (10%) Query: 1501 LTCIFGGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXX----XXXXXXXYKCIAFND 1555 L C G+P P++TW +G+ L A R YKCIA N Sbjct: 1092 LDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNK 1151 Query: 1556 HGE----VETSCVVG-IQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 G+ +E S V +++ PVI + N + + H V E V G+PPP W K Sbjct: 1152 TGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVI----GMPPPVFYWKK 1207 Query: 1609 NGNKLENDKEYNITTKEKT--SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 + + +E ++ T + + I+ K+S + YT+ A N AG S L +Y Sbjct: 1208 DNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264 Score = 50.0 bits (114), Expect = 7e-04 Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 4/90 (4%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G PP F++K +++ V EG+ + L+C +V IP P + W +G+E+ +I + ++H Sbjct: 266 GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHS 325 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 L I + G Y+ A N G S Sbjct: 326 ----LTIAEAFEEDTGRYSCFASNIYGTDS 351 Score = 50.0 bits (114), Expect = 7e-04 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 ++ GIPPP+V WY G +LEN + +I + I E + +Y+ ASN GT Sbjct: 291 IVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTD 350 Query: 1655 SVEVTLKVYD-KPSKPEGPVIMREISR 1680 S + + S EG E++R Sbjct: 351 STSAEIYIEGVSSSDSEGDPNKEEMNR 377 Score = 49.6 bits (113), Expect = 0.001 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 4/102 (3%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSI 789 +PP+ + L+S V +G V L VVG P P + W K ++ P G+ HS+ Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 326 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 TI + + +D G Y+ A N G TSA I +E + ++E Sbjct: 327 TIAEAFE-EDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSE 367 Score = 44.4 bits (100), Expect = 0.035 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 5/151 (3%) Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 P+ A T+ + H++ + K+ + E + A + + + EEP +PP Sbjct: 214 PIPA-DTRDNEVNHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPL---GQPP 269 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVIT 893 F + + V E ++L V P P + WY + + S I G L I Sbjct: 270 RFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIA 329 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 E D+G Y C ASN G S A + I+ Sbjct: 330 EAFEE-DTGRYSCFASNIYGTDSTSAEIYIE 359 Score = 43.6 bits (98), Expect = 0.061 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G+PPPE+ W NG + D + + +E + I L + + Y A+N G + Sbjct: 1096 VSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQN 1155 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREI 1678 S + L V K K + PVI+ ++ Sbjct: 1156 SFSLELSVVAKEVK-KAPVILEKL 1178 Score = 42.7 bits (96), Expect = 0.11 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%) Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 +S ++ YY+ E Q P + L++ ++L CI G+P P+V WY +GK+L+ Sbjct: 254 SSPSSLYYE---EPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELE 310 Query: 1524 TAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 + + N Y C A N +G TS + I+ Sbjct: 311 NSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359 Score = 42.7 bits (96), Expect = 0.11 Identities = 33/99 (33%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQN-----FDG 885 P+F Q ++ E + RV P P + WYR +I SP I Q + Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494 Query: 886 ENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 E I LVI V +E DSG + C ASN G S A++ + Sbjct: 495 EEICTLVIAEVFAE-DSGCFTCTASNKYGTVSSIAQLHV 532 Score = 42.7 bits (96), Expect = 0.11 Identities = 19/60 (31%), Positives = 30/60 (50%) Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 D S+ + I K +P +K LK+ + TC G+P PKV W++DGK++ Sbjct: 926 DESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQI 985 Score = 41.5 bits (93), Expect = 0.25 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 1/78 (1%) Query: 1106 PPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP +L++++V +G + + I + VRW+ +G E++ S I + G L Sbjct: 268 PPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT 327 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 I + +D G YSC N Sbjct: 328 IAEAFEEDTGRYSCFASN 345 Score = 39.9 bits (89), Expect = 0.75 Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNT 1650 T I GIP P+V W+K+G ++ E+ +E T + I+ YTI A+N Sbjct: 965 TCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANP 1024 Query: 1651 AGTSSVEVTLKVYDKP 1666 G S L V P Sbjct: 1025 QGRISCSGHLMVQSLP 1040 Score = 38.3 bits (85), Expect = 2.3 Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 I +P K L+N++ + + C G P PKV WYR+G Sbjct: 432 IAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREG 472 Score = 37.1 bits (82), Expect = 5.3 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 11/113 (9%) Query: 1561 TSCVVGIQQKPVITISN-EDIKQKHKVGDEWLVT--AVIEGIPPPEVIWYKNGNKLENDK 1617 T+ + G+ KP+I + Q + LV ++G P P+V WY+ G +E+ Sbjct: 420 TNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSP 479 Query: 1618 EYNITTK--------EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 ++ I K E+ + I E+ S +T ASN GT S L V Sbjct: 480 DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV 532 Score = 36.3 bits (80), Expect = 9.2 Identities = 45/191 (23%), Positives = 77/191 (40%), Gaps = 16/191 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D E + L+ +++ ++ W +G+ + P + + + L Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y CI ++ S + E++V V+ P I+ +LQN V +G+ E Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192 Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQK-LKIYDCDLDDAGEYSC----EV 1180 + + W KD I + I + D L I DAG Y+ E Sbjct: 1193 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252 Query: 1181 GNSKCTAILTV 1191 G CTA L + Sbjct: 1253 GIVSCTARLDI 1263 >UniRef50_Q0E9K8 Cluster: CG17800-PAN; n=84; Endopterygota|Rep: CG17800-PAN - Drosophila melanogaster (Fruit fly) Length = 2037 Score = 145 bits (351), Expect = 1e-32 Identities = 282/1393 (20%), Positives = 516/1393 (37%), Gaps = 155/1393 (11%) Query: 746 VRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDG--DTHSITILKPKKVKDEG 801 +RQ ++ + P P W K K +D I+K V+D G Sbjct: 260 IRQDRTIAIFCPAQAYPVPFYRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSG 319 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y NS G V+TV P +PP F V + T NP+ Sbjct: 320 KYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAV-------FTCQYTGNPI 372 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 +++W ++ + I SE + L I +V E D G Y+C N + A + Sbjct: 373 KTVSWMKDGKAIGHSEPV----------LRIESVKKE-DKGMYQCFVRNDQESAEASAEL 421 Query: 922 TIDVE-KVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREI--- 975 + ++ + E G +V L+C + T W + K+I+ D ++ Sbjct: 422 KLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQY 481 Query: 976 --IQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQDFEVK 1029 + D G+ KCI K + E S L V +P +IR+++ + Sbjct: 482 VTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV-YGLP-YIRQMEKKAIV 539 Query: 1030 EKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 + I+ + D +VWERD + + + F I + RN+ D+ Y+ Sbjct: 540 AGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNS---DQATYT 596 Query: 1089 CILRDE---SCTAEVTV-VELPPEIIT-RLQNQKVNKGNKATFEIELTKGDALVRWF--- 1140 C+ +++ S + V V +PP+++ + +N + + + KGD + + Sbjct: 597 CVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTT 656 Query: 1141 -----KDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 + ++ I +T ++ L I Y+C V + I E Sbjct: 657 APDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRANYTC-VARNAAGVIYHTAEL 715 Query: 1195 SINFTLRLPEFILVPAN------TDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISD 1247 +N P +IL P + +DA + + VTW K K SD Sbjct: 716 RVNVP---PRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSD 772 Query: 1248 ---VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRG 1302 V++ TL + + ++ Y C ++ + + + V+ PP+ + R +RG Sbjct: 773 NIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRG 832 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK------SASLTIKKVENTDAG 1356 L + + W +N+ + + +I + +SL+IK+ E +D+ Sbjct: 833 EPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSA 892 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 ++ N G D +N+ + + P P +L+ S+ + W +P + GNS + Y+ Sbjct: 893 LFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYD-GNSPLDRYI 951 Query: 1417 VEYQEIDTTEWISVKNIT----KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 +E++ W + + T+ +Q L ++Y R A N + S +SE Sbjct: 952 IEFKR-SRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEA----- 1005 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW------YRDGKKLKTAK 1526 V T ++P+ KP +NI EP + + P P+ W Y G KL Sbjct: 1006 VTIITAEEAPS-GKP-QNIKVEPVNQTTMRVTW--KPPPRTEWNGEILGYYVGYKLSNTN 1061 Query: 1527 ATY---------ENRXXXXXXXXXXXXXXXYKCI--AFNDHG-------EVETSCVVGIQ 1568 ++Y E Y + AFN G E + + Sbjct: 1062 SSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPS 1121 Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEG----IPPPEVIWYKNGNKLENDKEYNITTK 1624 Q P T Q +VG W V+ +E I +V++ + + K + T Sbjct: 1122 QPPSDTACTTLTSQTIRVG--W-VSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTA 1178 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--SRES 1682 +V+ LK+ + + A+ G V + +P PE P ++ + + Sbjct: 1179 SSDTVLH--GLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAA 1236 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 + + W+PP G+ +T+Y + K V ++ +L +N Y F V Sbjct: 1237 ILVSWRPPAQPNGI-ITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVT 1295 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 A +G E +S+ IV + VP+ + + F +++ P + Sbjct: 1296 ASTTIG--EGQQSKSIVAMPSDQVPAKIASF--------DDTFTATF--KEDAKMPCL-- 1341 Query: 1803 KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSD----DKIT 1858 V Q WK R++ L + + + R + G + + D IT Sbjct: 1342 AVGAPQPEITWKIKGVEFSANDRMRVLP-DGSLLIKSVNRQDAGDYSCHAENSIAKDSIT 1400 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 + P Q + +S +T+ ++T+K +P +P+ Y + +K G+ T V+V Sbjct: 1401 HKLIVLAPPQSPHVTLSATTTDALTVK-LKPHEGDTAPLHGYTLHYKPEFGEWETSEVSV 1459 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 +H IE + + N +G ++ + R + P P P I V Sbjct: 1460 DS--QKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTK--GQKPKLPEKPRFIE-V 1514 Query: 1979 GSNIVMTSWGTPEW-DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 SN V S W DGG P+ + + + + W ++ + + DL Y Sbjct: 1515 SSNSV--SLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWY 1572 Query: 2038 MIRIYARNEIGLS 2050 +RI A N G + Sbjct: 1573 NLRITAHNSAGFT 1585 Score = 128 bits (308), Expect = 2e-27 Identities = 226/1035 (21%), Positives = 400/1035 (38%), Gaps = 87/1035 (8%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEV-TVVELPPEIITRLQ--NQKVNKGNKATFEIEL 1130 L I++ V D G+Y C++ + V TV+ + + ++ Q V+ G A F + Sbjct: 308 LIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQY 367 Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189 T V W KDG I S + KK+ +Y C + + E + K Sbjct: 368 TGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGG-- 425 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF------T 1243 + P I + E + P + V + T +++W I + +++ T Sbjct: 426 RFDPPVIRQAFQ--EETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVT 483 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY--RIKR 1301 + DV L I +D Y C+ AKS KV V E K+ Y Y ++++ Sbjct: 484 VNGDVVSY-LNITSVHANDGGLYKCI---AKS----KVGVAEHSAKLNVYGLPYIRQMEK 535 Query: 1302 GSDV---TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE-NTDAGI 1357 + V TL+V P D IV + + + + +L I+ VE N+D Sbjct: 536 KAIVAGETLIVTCPVAGYPIDS-IVWERDNRALPINRKQKVFPNGTLIIENVERNSDQAT 594 Query: 1358 YKLRLENNCGHA---DVEMNVTILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTI 1412 Y +N G++ +E+ V + + P G+ I D S C N G++ + Sbjct: 595 YTCVAKNQEGYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSAT-C---TVNKGDTPL 650 Query: 1413 IYYVVEYQEIDTTEWISVKN----ITKTQTSIQNLKTNSSY-RFRAYAVNEVDISDASET 1467 Y + T + N ITKT I L S + R RA N ++ + Sbjct: 651 ELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIESVHARHRA---NYTCVARNAAG 707 Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-------DGK 1520 Y+ + + +P + D ++ C G P+P+VTW + + K Sbjct: 708 VIYHTAELRVNVPPRWILEPTDKAFAQ-GSDAKVECKADGFPKPQVTWKKAVGDTPGEYK 766 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNED 1579 LK + Y C A N G + ++ +Q P T + Sbjct: 767 DLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRN 826 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE--NDKEYNITTKEKT----SVIRIK 1633 Q + G+ ++ +G P ++W N +L+ ND Y I + + S + IK Sbjct: 827 --QTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIK 884 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 +RS S+ +T A+N G+ + + V + P P ++ + R SV + W P D Sbjct: 885 RTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGR-SVQLSWAQPY-D 942 Query: 1694 GGLELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 G L +Y IE + W ++ V +QKL+ Y R++A+N +G S+ Sbjct: 943 GNSPLDRYIIE-FKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQ 1001 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGG--SPIIDYKVEI 1806 + SE + I TA + PS ++ ++ +TW P +E NG + YK+ Sbjct: 1002 S--SEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSN 1059 Query: 1807 KQEGKKWKX----XXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 ++ +Q L + T Y I A N+IG P + ++K + Sbjct: 1060 TNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAG-PLSEEEKQFTAEG 1118 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 TP P + + TS+++ + W P ES G T ++ + + TK Sbjct: 1119 -TPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKT 1177 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + + +K+ ++ A G + S + + VP PT ++ ++G+ Sbjct: 1178 ASSDTVLHGLKKYTNYTMQVLATTAGGDGV--RSVPIHCQTEPDVPEAPT-DVKALVMGN 1234 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 ++ SW P G + Y + + + KV + F +L +N Y Sbjct: 1235 AAILVSWRPPAQPNGI-ITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFW 1293 Query: 2041 IYARNEIGLSEPLES 2055 + A IG + +S Sbjct: 1294 VTASTTIGEGQQSKS 1308 Score = 85.0 bits (201), Expect = 2e-14 Identities = 86/334 (25%), Positives = 133/334 (39%), Gaps = 36/334 (10%) Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK-KPKAQYVDEGSDIL 652 S T +I +A + D G + V +L P +K P Q VD G + Sbjct: 305 SGTLIIKDAVVEDSGKYLCVVNNSVGGESVET--VLTVTAPLSAKIDPPTQTVDFGRPAV 362 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 C+ P ++W+ G+ I E VL+I +VKK +G Y Sbjct: 363 FTCQYTGNPIKTVSWMKDGKAIGHSE--------------PVLRIESVKKEDKGMYQCFV 408 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW---- 768 N + A LK+ G +PP + + + + G SV L GNP P I+W Sbjct: 409 RNDQESAEASAELKLG-GRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDG 467 Query: 769 ---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 N++ +GD S + D G+Y A++ G+AE SA + V Sbjct: 468 KKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV--- 524 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 P +I + ++ + T+ + V P+ SI W R+N + P + F Sbjct: 525 ---YGLP--YIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRAL-PINRKQKVF-- 576 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 N L+I NV+ D Y CVA N G S+ G+ Sbjct: 577 PNGTLIIENVERNSDQATYTCVAKNQEGYSARGS 610 Score = 83.8 bits (198), Expect = 5e-14 Identities = 274/1332 (20%), Positives = 477/1332 (35%), Gaps = 164/1332 (12%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 ++ T + + EP A + F ++++ TI + PVP WY+ E Sbjct: 229 LSATKGRLVITEPVGSVAPRVNKKDGFSHDSIRQDRTIAIFCPAQAYPVPFYRWYKFIEG 288 Query: 873 ISPSETITQNFDGENIELVITNVDSEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + + + N + + + D+ + DSG Y CV +NS G S + V Sbjct: 289 TTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGES--VETVLTVTAPLSA 346 Query: 932 KHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 K + + G+ + CQ T + + T W + K I H E + Sbjct: 347 KIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIG---HSEPV-------LRIESV 396 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETI-----PEFIRKLQDFEVKE--KDVAILEVEINS 1042 D G+ +C V++ + S + + P IR+ E E V + V + Sbjct: 397 KKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGN 456 Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIR---KLYIRNTSVH--DEGEYSCILRDESCT 1097 T ++ WE DG+ I ++Y + + Y+ TSVH D G Y CI + + Sbjct: 457 PTPEISWELDGKKI-ANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGV 515 Query: 1098 AE----VTVVELPPEIITRLQNQKVNKGNK--ATFEIELTKGDALVRWFKDGSEIQFSNH 1151 AE + V LP I +++ + + G T + D++V W +D + + Sbjct: 516 AEHSAKLNVYGLP--YIRQMEKKAIVAGETLIVTCPVAGYPIDSIV-WERDNRALPINRK 572 Query: 1152 IQLTIDG--------KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP 1203 ++ +G + Y C + YS G+ + ++ + +F Sbjct: 573 QKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSAR-GSLEVQVMVPPQVVPFDFG---E 628 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKF-----TLISDVKKR--TLIIR 1256 E I + A TV D L++ W + LI+ +R L I Sbjct: 629 ETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTGVGRLMSNDGILITKTTQRISMLSIE 688 Query: 1257 KCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315 + YTCV +A E+ V PP+ + + +GSD + FP Sbjct: 689 SVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKADGFP 748 Query: 1316 QPNDEW---IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG----- 1367 +P W + ++ K +I + +L + ++ T+ G Y N G Sbjct: 749 KPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSA 808 Query: 1368 ------HADVEMNVTILDKPSPPGKPNILEIDSSS---INICWD------EPENTGNSTI 1412 A E + ++ + G+P +L+ ++ I I W+ +P+N TI Sbjct: 809 VIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTI 868 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 +EI +T +S +I +T+ S S F A N DAS Sbjct: 869 ------REEILSTGVMSSLSIKRTERS-------DSALFTCVATNAFGSDDAS----INM 911 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 +++E P + LK + + ++L+ + Y K A + +R Sbjct: 912 IVQEV----PEMPYALK-VLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDR 966 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI----KQKHKVGD 1588 +N E + + V I+ E+ Q KV Sbjct: 967 VIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEP 1026 Query: 1589 EWLVTAVIEGIPPP------EVIWYKNGNKLEN-DKEY-----NITTKE-KTSVIRIKEL 1635 T + PPP E++ Y G KL N + Y N T+E K + ++ L Sbjct: 1027 VNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNL 1086 Query: 1636 KRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW-KPPL 1691 + I+A N G S E PS+P ++ +++ + W PPL Sbjct: 1087 RVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPL 1146 Query: 1692 DDGGLELTKYAI------EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 + + Y + E ++ + K A D + L + Y +V+A Sbjct: 1147 ESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDT-----VLHGLKKYTNYTMQVLATT 1201 Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G + + S PI +T DVP + N ++ ++W P + G I Y V Sbjct: 1202 AGG--DGVRSVPIHCQTEPDVPE-APTDVKALVMGNAAILVSWRPPAQPNGI-ITQYTVY 1257 Query: 1806 IKQEGKKWKXXXX---XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 K EG + + +L N Y+F + A IG K + Sbjct: 1258 SKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEG----QQSKSIVA-- 1311 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTE--PESNGGSPITNYIIEFKTVKGKSWTKI-VTVG 1919 P Q + S + + T K P G+P + K V+ + ++ V Sbjct: 1312 -MPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPD 1370 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 GS+ I+++ +D + AEN S+ +S + +L V +PP +P Sbjct: 1371 GSL---LIKSVNRQDAGDYSCHAEN----SIAKDSITHKL----IVLAPPQSPHVTLSAT 1419 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMI 2039 + +T P APL GY + + W E +V V++ K NI L Y + Sbjct: 1420 TTDALTVKLKPHEGDTAPLHGYTLHYKPEFGE-W-ETSEVSVDSQKHNIEGLLCGSRYQV 1477 Query: 2040 RIYARNEIGLSE 2051 N IG E Sbjct: 1478 YATGFNNIGAGE 1489 Score = 79.4 bits (187), Expect = 1e-12 Identities = 103/483 (21%), Positives = 197/483 (40%), Gaps = 39/483 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH-MY 691 PP + + + ++ G + L+C P P+I+W G++I ++ V ++ Sbjct: 429 PPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDV 488 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L IT+V G Y +A ++ G A L + P + + K IV GE+ Sbjct: 489 VSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV----YGLPYIRQMEKKAIV-AGET 543 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 +I++ V G P +I W ++N+ + + ++ I ++ D+ YT A+N E Sbjct: 544 LIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQE 603 Query: 812 GI-AETSAVITVEEPTE----ENAEPPLFINRFQEIT-VKEKGTIKLVARVTRNPVPS-- 863 G A S + V P + + E + +N T KG L T P P+ Sbjct: 604 GYSARGSLEVQVMVPPQVVPFDFGEETINMNDMVSATCTVNKGDTPLELYWTTAPDPTTG 663 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + +N+ I ++T TQ +IE V +Y CVA N+AG H A + + Sbjct: 664 VGRLMSNDGILITKT-TQRISMLSIESVHAR-----HRANYTCVARNAAGVIYHTAELRV 717 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG-- 979 +V ++ K++ +G +EC+ W + G +++++ + Sbjct: 718 NVPPRWILEPTDKAF--AQGSDAKVECKADGFPKPQVTWKKAVGDTPG-EYKDLKKSDNI 774 Query: 980 --RXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDV 1033 + G C + ++ +++ + PEF KL++ + + Sbjct: 775 RVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEP 834 Query: 1034 AILEVEINSE-TADVVWERDGEIIKPKK-NKYDFEKR----GHIRKLYIRNTSVHDEGEY 1087 A+L+ E E ++W + + PK N+Y + G + L I+ T D + Sbjct: 835 AVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALF 894 Query: 1088 SCI 1090 +C+ Sbjct: 895 TCV 897 Score = 73.3 bits (172), Expect = 7e-11 Identities = 57/239 (23%), Positives = 101/239 (42%), Gaps = 14/239 (5%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L +E+ + H + T A++ +PP + +P + +GSD +EC+ Sbjct: 685 LSIESVHARHRANYTCVARNAAGVIYHTAELRVNVPPRWILEPTDKAFAQGSDAKVECKA 744 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P+P + W K P E + ++ + L + N++K EG Y A+N G Sbjct: 745 DGFPKPQVTWK-KAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIG 803 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 + L V+ I + PP+ E L++ R+GE +L + G I W NN + Sbjct: 804 -SGLSAVIMISV--QAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDP 860 Query: 778 LPTK---------SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 S G S++I + ++ D ++T A N+ G + S + V+E E Sbjct: 861 KNDNRYTIREEILSTGVMSSLSIKRTER-SDSALFTCVATNAFGSDDASINMIVQEVPE 918 Score = 46.4 bits (105), Expect = 0.009 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV----ATLVIREVFPEDAGTF 581 T+ C + YP P W++ I+ + Q +D V TL+I++ ED+G + Sbjct: 265 TIAIFCPAQAYPVPFYRWYK---FIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKY 321 Query: 582 TCVAKNAAGFASSTTELIVEAPLS 605 CV N+ G S T L V APLS Sbjct: 322 LCVVNNSVGGESVETVLTVTAPLS 345 Score = 43.6 bits (98), Expect = 0.061 Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 ++ ++ K G T+ C V GYP I W R + ++ +++ + TL+I Sbjct: 529 YIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPN----GTLIIE 584 Query: 572 EV-FPEDAGTFTCVAKNAAGF-ASSTTELIVEAP 603 V D T+TCVAKN G+ A + E+ V P Sbjct: 585 NVERNSDQATYTCVAKNQEGYSARGSLEVQVMVP 618 Score = 43.6 bits (98), Expect = 0.061 Identities = 27/102 (26%), Positives = 50/102 (49%), Gaps = 7/102 (6%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV- 565 ++ P ++ + K GS + EC+ +G+P+PQ+TW + A+ +++ DN+ Sbjct: 718 NVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTW--KKAVGDTPGEYKDLKKSDNIR 775 Query: 566 ---ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI-VEAP 603 TL + + + G + C A N G S +I V+AP Sbjct: 776 VEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAP 817 Score = 42.7 bits (96), Expect = 0.11 Identities = 64/282 (22%), Positives = 113/282 (40%), Gaps = 17/282 (6%) Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 +KK+ T V+A G+ + + +T E + P+ +K++++ ++++S + Sbjct: 1187 LKKYTNYTMQVLATTAGGDGVRSVPIHCQT-EPDVPEAPTDVKALVMGNA-AILVSWRPP 1244 Query: 760 GNPRPTIT-WCKNNKPVKA-LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE-T 816 P IT + +K A TK+ H + +++ Y S I E Sbjct: 1245 AQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQ 1304 Query: 817 SAVITVEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 + V P+++ P I F + T K K+ P P ITW S Sbjct: 1305 QSKSIVAMPSDQ---VPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSA 1361 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 ++ + DG L+I +V+ + D+GDY C A NS K S ++ + + H+ Sbjct: 1362 NDRMRVLPDGS---LLIKSVNRQ-DAGDYSCHAENSIAKDSITHKLIVLAPPQS--PHVT 1415 Query: 936 KSYETEEGKTVILECQTSHTVSTKWY--HNKKEISGMDHREI 975 S T + TV L+ T Y H K E + E+ Sbjct: 1416 LSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEV 1457 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 5/97 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVAT-- 567 P F EKLR + G +C+ +G I W + P D + ++ ++T Sbjct: 818 PEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGV 877 Query: 568 ---LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 L I+ D+ FTCVA NA G ++ +IV+ Sbjct: 878 MSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQ 914 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM----YYDDDNV 565 P+ + + + G +V +C G P P+I+W I + +Q+ + D V Sbjct: 430 PVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVV 489 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + L I V D G + C+AK+ G A + +L V Sbjct: 490 SYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNV 524 Score = 40.7 bits (91), Expect = 0.43 Identities = 24/73 (32%), Positives = 39/73 (53%), Gaps = 4/73 (5%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C G P+P+ITW + + ++ D +L+I+ V +DAG ++C A+N+ Sbjct: 1340 CLAVGAPQPEITWKIKGVEFSANDRMRVLPD----GSLLIKSVNRQDAGDYSCHAENSIA 1395 Query: 591 FASSTTELIVEAP 603 S T +LIV AP Sbjct: 1396 KDSITHKLIVLAP 1408 Score = 38.7 bits (86), Expect = 1.7 Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 KP P KP +E+ S+S+++ + + G + ++VVE ++ D EW + N K + Sbjct: 1502 KPKLPEKPRFIEVSSNSVSLHF-KAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNN 1560 Query: 1440 --IQNLKTNSSYRFRAYAVNEVDISDA 1464 + +L+ + Y R A N + A Sbjct: 1561 YVVLDLEPATWYNLRITAHNSAGFTVA 1587 >UniRef50_P54296 Cluster: Myomesin-2; n=33; Euteleostomi|Rep: Myomesin-2 - Homo sapiens (Human) Length = 1465 Score = 144 bits (348), Expect = 3e-32 Identities = 111/403 (27%), Positives = 171/403 (42%), Gaps = 13/403 (3%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE 1724 P P G V EISR V + W+PP G L Y IEK + W +V A Sbjct: 511 PGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGTWQRVNAQTAVRSP 568 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 Y + L E Y+FRV++ N G SE E + PI + VPS S Sbjct: 569 RYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKT-S 627 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840 V + W ++ Y V+ G W+ R + L+ Y FR+ Sbjct: 628 VVVQW--DRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVK 685 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N +G S D I + LT PS P + S+TL W P+ +GGSPI Y Sbjct: 686 AVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL 1959 ++ + V K+W ++ + ++ + E F+I+A N G+ P++ S+ + Sbjct: 746 YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805 Query: 1960 EKHATVPSP-PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 E T+P P P L V ++ W P + G +P+ GY + R+ W+ V + Sbjct: 806 EAW-TMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVDQ 864 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + + DL + TY+ R+ A N G+ +P ++ EP V Sbjct: 865 TTTASRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLV 907 Score = 64.9 bits (151), Expect = 2e-08 Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 9/163 (5%) Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 QP EW + ++K+ K TK ASL+ + D G+Y LR+ + G D + Sbjct: 311 QPRAEWYRDDLLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFL 370 Query: 1376 TILDK----PSPPGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 + D PG P L+ ++ + + W P T S ++ Y V+ E+ T W+ Sbjct: 371 FVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWV 430 Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + + + + L SY FR AVN IS S ++ Sbjct: 431 QCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSD 473 Score = 64.5 bits (150), Expect = 3e-08 Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 31/224 (13%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P + ++ V + W P + SP+ Y ++ V +W + + ++ Sbjct: 383 PGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKY 442 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPT---------------ESQSVRLEKH-------- 1962 + + E IFR+ A N+ G+S P+ Q+V LE Sbjct: 443 PVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQD 502 Query: 1963 -----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV- 2016 A VP PPT + + N V+ SW P G PL+ Y I V W V Sbjct: 503 DLEGDAQVPGPPTG-VHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGTWQRVN 560 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + V + ++ + DL E +Y+ R+ + N GLSEP E P + Sbjct: 561 AQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQ 604 Score = 56.8 bits (131), Expect = 6e-06 Identities = 66/316 (20%), Positives = 116/316 (36%), Gaps = 46/316 (14%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539 ++P + L++ T ++L G P P V WY+DG + A + R Sbjct: 152 RAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGV 211 Query: 1540 XXXXX-------XXXYKCIAFNDHGEVETSCV-------------------VGIQQKPVI 1573 Y +A N HG+V T+ +G+ +I Sbjct: 212 HTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMI 271 Query: 1574 TISNEDIKQKHKVGDEW-------------LVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 ++ D++ K G + LVT ++ + P WY++ L+ K Sbjct: 272 PYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQP-RAEWYRDDLLLKESKWTK 330 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP----SKPEGPVIMR 1676 + E + + L + YT+ + G + L V D P P+ ++ Sbjct: 331 MFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVTDHSAFLFVRDADPLVTGAPGAPMDLQ 390 Query: 1677 --EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 + +R+ V + WKPP + Y +++ E N W++ D + Y + L E Sbjct: 391 CHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEG 450 Query: 1735 CEYMFRVIAQNPVGFS 1750 Y+FRV A N G S Sbjct: 451 RSYIFRVRAVNSAGIS 466 Score = 56.0 bits (129), Expect = 1e-05 Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 7/177 (3%) Query: 1881 SVTLKWT---EPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 +VTLK T P+ P + + +K WTK+ G ++ + DE + Sbjct: 294 TVTLKCTMLVTPDLKRVQPRAEWYRDDLLLKESKWTKMFFGEGQA-SLSFSHLHKDDEGL 352 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGG 1995 + + + GV+ + VR + V P AP++++ +N V+ +W P Sbjct: 353 YTLRIVSRGGVTDHSAFLFVR-DADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTE 411 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 +P++GY + +V W++ V K+ + L E +Y+ R+ A N G+S P Sbjct: 412 SPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRP 468 Score = 54.4 bits (125), Expect = 3e-05 Identities = 57/239 (23%), Positives = 103/239 (43%), Gaps = 27/239 (11%) Query: 493 DKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK 551 DKL +E+ T EE+ S AP + +LR + +V+ V+G+P P + W++ ++I Sbjct: 137 DKL-AWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLIC 195 Query: 552 PSQDFQMYYDDDN--VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV------EAP 603 + + Y + N V TL I +D T++ VA NA G S+ ++V E P Sbjct: 196 QAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEP 255 Query: 604 LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-- 661 G + + LE TF + EG + L+C ++ P Sbjct: 256 FRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRR--------EGETVTLKCTMLVTPDL 307 Query: 662 ---EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 +P W ++ + ++ + + + + L +++ K EG YT+ V+R G Sbjct: 308 KRVQPRAEW-YRDDLLLKESKWTKMFFGEGQ---ASLSFSHLHKDDEGLYTLRIVSRGG 362 Score = 54.4 bits (125), Expect = 3e-05 Identities = 62/306 (20%), Positives = 121/306 (39%), Gaps = 17/306 (5%) Query: 1362 LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 + N +DV L PS P +L D S+ + W P+ +G S I+ Y ++ +E Sbjct: 692 MSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKRE 751 Query: 1422 IDTTEWISVKNITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 + W V + T ++ L S Y F+ AVN I + S+ +E++K T Sbjct: 752 VHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMP 811 Query: 1480 Q-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD------GKKLKTAKATYENR 1532 + P + + + ++ G P ++ D G+ + + T +R Sbjct: 812 EPGPAYDLTFCEVRDTSLVMLWKAPVYSG-SSPVSGYFVDFREEDAGEWITVDQTTTASR 870 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHG---EVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589 ++ A N +G +TS V ++ +P + + ++ G+ Sbjct: 871 -YLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQ---GNI 926 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 +L E + W K+ ++ +D+ + I T S + +K + Y++ S+ Sbjct: 927 YLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSD 986 Query: 1650 TAGTSS 1655 T G SS Sbjct: 987 TDGVSS 992 Score = 51.2 bits (117), Expect = 3e-04 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNT 1650 +T + G P PEVIW+KN ++ + +++ ++ V + IK + S KY+I N Sbjct: 1364 LTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNK 1423 Query: 1651 AGTSSVEVTLKVYDKPSK 1668 G ++VT+ VY K Sbjct: 1424 YGGEKIDVTVSVYKHGEK 1441 Score = 49.2 bits (112), Expect = 0.001 Identities = 37/193 (19%), Positives = 78/193 (40%), Gaps = 5/193 (2%) Query: 403 KRLNPFEIFYTP--VEVRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWYVQK 460 K +P ++ TP + ++C F V + + E + I + W + + Sbjct: 1233 KSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICE 1292 Query: 461 HLTEEKGWVPAQYLMDENNYTQYLQ---KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLR 517 ++KG + ++N+ + L + +E + F+ E++ + Sbjct: 1293 PTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPD 1352 Query: 518 PKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 +G T+ C V G P P++ WF+ I+ S+ F + + ++ I+ V ED Sbjct: 1353 VVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSED 1412 Query: 578 AGTFTCVAKNAAG 590 +G ++ KN G Sbjct: 1413 SGKYSINIKNKYG 1425 Score = 44.8 bits (101), Expect = 0.026 Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 8/155 (5%) Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSK 1668 +N E N ++ K +++ + L ++ I A N AG S + + P Sbjct: 755 KNWHEVN-SSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEP 813 Query: 1669 -PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 P + E+ S+ + WK P+ G ++ Y ++ E D WI V Sbjct: 814 GPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVDQTTTASRYLK 873 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIK 1761 + L + Y+FRV A N G + + SEP++++ Sbjct: 874 VSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE 908 Score = 44.4 bits (100), Expect = 0.035 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 8/106 (7%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P + EG + L C + P+P++ W ++I E+ SV +E ++ ++ +T+ Sbjct: 1351 PDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTS 1410 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEK----EPPQVIEP 740 G Y++ N+ G + + + + K GEK PPQ +P Sbjct: 1411 E---DSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKP 1453 Score = 42.3 bits (95), Expect = 0.14 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GENIELVITNVDSEID 900 +T+ E T+ L V NP P + W++N++ I SE + + + + + I V SE D Sbjct: 1354 VTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSE-D 1412 Query: 901 SGDYKCVASNSAGKSSHGARVTI 923 SG Y N G V++ Sbjct: 1413 SGKYSINIKNKYGGEKIDVTVSV 1435 Score = 41.1 bits (92), Expect = 0.33 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 6/102 (5%) Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVK 1431 +VT++ PS PG+ +S+ + WD P++ ++ Y V+ T W + K Sbjct: 607 DVTVV--PSAPGRVLASRNTKTSVVVQWDRPKH--EEDLLGYYVDCCVAGTNLWEPCNHK 662 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 I + + L T Y FR AVN V +S+ S+ ++ KV Sbjct: 663 PIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKV 704 Score = 41.1 bits (92), Expect = 0.33 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI 1357 I G + L P P W N + I+ +H ++ +K S+TIK V + D+G Sbjct: 1356 IMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGK 1415 Query: 1358 YKLRLENNCGHADVEMNVTI 1377 Y + ++N G +++ V++ Sbjct: 1416 YSINIKNKYGGEKIDVTVSV 1435 Score = 40.7 bits (91), Expect = 0.43 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 8/102 (7%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII----SPSE-TITQ 881 E + P + R + TV E+ ++KL V P P + WY++ +I P + I Sbjct: 148 ERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIES 207 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 N+ +E+ + D D+ Y VA+N+ G+ S A V + Sbjct: 208 NYGVHTLEINRADFD---DTATYSAVATNAHGQVSTNAAVVV 246 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-- 1438 P PP + EI + + + W+ P G ++Y+ +E + + W V T ++ Sbjct: 511 PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYF-IEKSVVGSGTWQRVNAQTAVRSPR 569 Query: 1439 -SIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 ++ +L SY FR + N +S+ SE T Sbjct: 570 YAVFDLMEGKSYVFRVLSANRHGLSEPSEIT 600 Score = 38.3 bits (85), Expect = 2.3 Identities = 23/102 (22%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Query: 731 EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDT 786 EK ++I L ++ + +G+++ L+ V GNP P + W KN++ ++ K + Sbjct: 1340 EKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAK 1399 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + +K +D G Y++ +N G + ++V + E+ Sbjct: 1400 YVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEK 1441 >UniRef50_Q9VS29 Cluster: CG32387-PA, isoform A; n=15; Endopterygota|Rep: CG32387-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 1770 Score = 142 bits (344), Expect = 9e-32 Identities = 302/1398 (21%), Positives = 513/1398 (36%), Gaps = 133/1398 (9%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--PVKALPTKSDGDTHSITIL 792 P V+E + V Q E +L G P P +W +N P+ L I + Sbjct: 204 PSVVEHTAHVQVSQDEGAVLLCVAQGCPSPEYSWFTHNGAGPLPVLSGPRVRLLGPILAI 263 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 + +D GVY A N G A +TV P + P + ++V GT + Sbjct: 264 EAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNV-------LSVHMGGTAEF 316 Query: 853 VARVTRNPVP----SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 VT N P +I WY++ + S + LV+ V E + G Y+CV Sbjct: 317 RCLVTSNGSPVGMQNILWYKDGRQLPSSGRVEDT-------LVVPRVSRE-NRGMYQCVV 368 Query: 909 SNSAGKSSHG-ARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNK 964 G + A + + D V ++++ + G V L+C + T W + Sbjct: 369 RRPEGDTFQATAELQLGDAPPVLLYSFIEQTLQP--GPAVSLKCSAAGNPTPQISWTLDG 426 Query: 965 KEISG----MDHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKDQETSTMLVVKETIP-- 1017 + M + I G D G CI +++ + I Sbjct: 427 FPLPSNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGL 486 Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 +IR + + L+ + + + WER G + P + + G + + Sbjct: 487 PYIRLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGREL-PDDIRQRVQPDGSLTISPV 545 Query: 1077 RNTSVHDEGEYSCILRDESC-----TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131 + S D G Y+C R++ + EVTV+ +PP I + + +G + ++ Sbjct: 546 QKNS--DSGVYTCWARNKQGHSARRSGEVTVI-VPPSIEPFAFQEGLAEGMRTRTVCGVS 602 Query: 1132 KGDALVR--WFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYSCEVGNS----K 1184 +GD ++ W KDG + +T +D L I +GEY+C N K Sbjct: 603 RGDPPLKLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIK 662 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYK----KKSVIEDT 1239 TA+L V+ P + + P V N L + T + W K K E+ Sbjct: 663 YTALLQVKVPP-RWIVE-PVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSKSGEYEEV 720 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV--VEFPPKIVDYEREY 1297 + + +L+++ ED + Y C + T KV V P R Sbjct: 721 RERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSV 780 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSI------DSKSASLTIKKV 1350 +K+G L N W+ + K + + K S+ D SA L I+ V Sbjct: 781 MVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTV 840 Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 + TD+G Y R N G+ + + + + P PP I S S+NI W +P+ G Sbjct: 841 DATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIKW-QPKTLGTG 899 Query: 1411 TIIYYVVEYQEID---TTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + Y+VE++E D +W I VK+ I+NLK + Y FR A S S Sbjct: 900 DVTKYIVEFREADPLFVDQWQQIEVKDPPHFNAMIENLKPATRYAFRVIAEGSAGRSAPS 959 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK-----VTWYRDGK 1520 + ++I T+ Q P P +++ P EL I P P+ + Y G Sbjct: 960 Q-----ELIVRTEPQRPA--GPPLSLSARPLSSTEL-LISWVAPLPELRHGDIQGYNVGY 1011 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA----FNDHGEVETSCVVGIQQKPVITIS 1576 KL ++ T N +A + + G +P + Sbjct: 1012 KLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQT 1071 Query: 1577 NEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNG-------------NKLENDKEYNI 1621 ED+ + V L + ++ P I++ NG + ++ K+ Sbjct: 1072 MEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVE 1131 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI--S 1679 + K + + L++ + + A G V L + + PE P ++ + S Sbjct: 1132 SRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSS 1191 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI--KVADVDRDVETYCIQKLNENCEY 1737 +S+ I W PP + G+ +TKY++ + + + + Y + L+ + EY Sbjct: 1192 SQSLYISWLPPNEPNGV-ITKYSLYTRVVNGREELNNEKRSLPSQQAYYEAKGLHPHMEY 1250 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 F V A VG E S T +P+ S +T P G Sbjct: 1251 QFWVTASTRVG--EGKSSRVSSQITTNRIPARIISFGGPVVRPWRST-VT-LPCTAVGKP 1306 Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 +K ++ I L + + N IGT D++ Sbjct: 1307 KREWFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGT-------DRL 1359 Query: 1858 TIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 T + PP+ P +V S +TS S+ + W + G +PIT Y + ++ G + + Sbjct: 1360 THTLIVQVPPTAPVLYVTS-ATSSSILMHW-KCGFTGNAPITGYTLFYRRANGNTDEMQL 1417 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 + S HE ++ + +SA+N VG S + VR + + TA L Sbjct: 1418 SRHASSHE--LKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPN 1475 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT---KTMWMEVGKVDVNTLKFNIRDLSE 2033 + + SW D G PLL + + R VT W+ V + I +L Sbjct: 1476 STSLLVRLHSWP----DNGCPLLYFVLQYRAVTDDPDAEWVLVSNALKPQRRIVINNLQP 1531 Query: 2034 NHTYMIRIYARNEIGLSE 2051 + Y +R+ A N G+S+ Sbjct: 1532 STLYQLRMEAHNVAGISQ 1549 Score = 103 bits (248), Expect = 4e-20 Identities = 140/600 (23%), Positives = 227/600 (37%), Gaps = 60/600 (10%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXXXXXXXX 1545 + +T E + L C G P ++ W R G++L + + Sbjct: 492 IPKVTAVSGETLNLKCPVAGYPIEEIHWERGGRELPDDIRQRVQPDGSLTISPVQKNSDS 551 Query: 1546 XXYKCIAFNDHGE-VETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 Y C A N G S V + P I E + + + V V G PP Sbjct: 552 GVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRT---VCGVSRGDPPL 608 Query: 1603 EVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 ++IW K+G+ L + N+T ++ +S++ I L +HS +YT A N A L+ Sbjct: 609 KLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQ 668 Query: 1662 VYDKPSKPEGPV---------IMREISRESV---TIEWKPPLDDGGLELTKYAIEKHEPD 1709 V P PV IM + V +I WK G + +Y + P Sbjct: 669 VKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKAT---GSKSGEYEEVRERPF 725 Query: 1710 N----NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 N + + V D E + + + N + Q V S S ++ Sbjct: 726 TKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSST----SRSVM 781 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR 1825 V ++ + I W S KN +P +YK+ +KQE A Sbjct: 782 VKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATP-------DGVSAE 834 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 +Q +++ T + R S Y +D ++ + PP P + +SRSV +K Sbjct: 835 LQIRTVDATDSGPYFCR----ASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIK 890 Query: 1886 WTEPESNGGSPITNYIIEFKTVKG---KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 W +P++ G +T YI+EF+ W +I IEN+K FR+ A Sbjct: 891 W-QPKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDPPHFNAMIENLKPATRYAFRVIA 949 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW--GTPEWDGGAPLLG 2000 E + G S P++ VR E P+ P L R + S ++ SW PE G + G Sbjct: 950 EGSAGRSAPSQELIVRTEPQR--PAGPPLSLSARPLSSTELLISWVAPLPELRHG-DIQG 1006 Query: 2001 YNIAIR-----DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEP 2052 YN+ + + G D + + L++ Y + + A N++G LSEP Sbjct: 1007 YNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEP 1066 Score = 74.1 bits (174), Expect = 4e-11 Identities = 110/478 (23%), Positives = 177/478 (37%), Gaps = 36/478 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM-Y 691 PP Q + G + L+C P P I+W G + + + +H Sbjct: 388 PPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDV 447 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S + I++V G Y +A NR G L I I + + GE+ Sbjct: 448 ISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYG-----LPYIRLIPKVTAVSGET 502 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L V G P I W + + + + S+TI +K D GVYT A N + Sbjct: 503 LNLKCPVAGYPIEEIHWERGGRELPDDIRQRVQPDGSLTISPVQKNSDSGVYTCWARNKQ 562 Query: 812 G-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRN 869 G A S +TV P + EP FQE + T + V V+R P + W ++ Sbjct: 563 GHSARRSGEVTVIVPP--SIEP----FAFQEGLAEGMRT-RTVCGVSRGDPPLKLIWLKD 615 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + + L+ S SG+Y CVA N A + + A + + V Sbjct: 616 GDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRW 675 Query: 930 FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 V+ + + E + ++L CQ T S W SG ++ E+ + Sbjct: 676 IVEPVDAN--VERNRHIMLHCQAQGVPTPSIVWKKATGSKSG-EYEEVRERPFTKLLGNG 732 Query: 988 XXXXXDV-----GVIKCIVKDQ-ETSTMLVVK---ETIPEFIRKLQDFEVKEKDVAILEV 1038 V G C + T V++ + P F + VK+ D A+L+ Sbjct: 733 SLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQC 792 Query: 1039 EINSE-TADVVWERDGE-IIKPKKN-----KYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 ++ + ++VW R G+ + P N K + G +L IR D G Y C Sbjct: 793 AVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSGPYFC 850 Score = 67.3 bits (157), Expect = 4e-09 Identities = 111/496 (22%), Positives = 189/496 (38%), Gaps = 48/496 (9%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 DEG+ +L C P P+ +W F P + V + + +L I V Sbjct: 218 DEGAVLL--CVAQGCPSPEYSW-FTHNGAGP---LPVLSGPRVRLLGPILAIEAVTGEDS 271 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G Y A N GEAS + L + T P QV + V G + V N P Sbjct: 272 GVYKCTAGNVGGEASAELRLTVAT----PIQVEISPNVLSVHMGGTAEFRCLVTSNGSPV 327 Query: 766 ----ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 I W K+ + LP S G ++ ++ G+Y EG + T Sbjct: 328 GMQNILWYKDGRQ---LP--SSGRVEDTLVVPRVSRENRGMYQCVVRRPEG---DTFQAT 379 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---T 878 E + PP+ + F E T++ + L NP P I+W + + PS Sbjct: 380 AE--LQLGDAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPL-PSNGRFM 436 Query: 879 ITQ--NFDGENIELV-ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 I Q G+ I V I++V E D G+Y C+A N AG+ H AR +++ + +++ + Sbjct: 437 IGQYITVHGDVISHVNISHVMVE-DGGEYACIAENRAGRVQHAAR--LNIYGLPYIRLIP 493 Query: 936 KSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 K G+T+ L+C + W +E+ D R+ +Q D Sbjct: 494 K-VTAVSGETLNLKCPVAGYPIEEIHWERGGRELPD-DIRQRVQPD-GSLTISPVQKNSD 550 Query: 994 VGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE------KDVAILEVEINSETADV 1047 GV C ++++ + E ++ F +E + + V + Sbjct: 551 SGVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEGMRTRTVCGVSRGDPPLKL 610 Query: 1048 VWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VE 1104 +W +DG+ + + L I + S GEY+C+ ++ + + T V+ Sbjct: 611 IWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVK 670 Query: 1105 LPPEIITRLQNQKVNK 1120 +PP I + V + Sbjct: 671 VPPRWIVEPVDANVER 686 Score = 50.0 bits (114), Expect = 7e-04 Identities = 49/229 (21%), Positives = 91/229 (39%), Gaps = 14/229 (6%) Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 H E T A + +PP + +P V+ I+L C+ +P P I Sbjct: 646 HSGEYTCVAKNPAAEIKYTALLQVKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIV 705 Query: 667 W-LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W G + E + + + S+L + +VK+ +EG Y A N G + V+ Sbjct: 706 WKKATGSKSGEYEEVRERPFTKLLGNGSLL-LQHVKEDREGFYLCQANNGIG-TGIGKVI 763 Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV------KALP 779 ++K P +S++V++G++ +L V G+ I W ++ K + Sbjct: 764 QLKVNSS--PYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKIS 821 Query: 780 TKSDGDTHSITI---LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 K + ++ ++ D G Y +A N G + + V+EP Sbjct: 822 VKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEP 870 Score = 43.2 bits (97), Expect = 0.081 Identities = 40/178 (22%), Positives = 73/178 (41%), Gaps = 9/178 (5%) Query: 1795 GGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTS 1853 G +PI Y + ++ G + ++ L +TYQ + A+N++GTS T Sbjct: 1394 GNAPITGYTLFYRRANGNTDEMQLSRHASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTI 1453 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 T G++ P P + + S S+ ++ N G P+ ++++++ V Sbjct: 1454 LHVRTQGQS---PGHPASTALLAPNSTSLLVRLHSWPDN-GCPLLYFVLQYRAVTDDPDA 1509 Query: 1914 KIVTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 + V V ++ I N++ R+ A N G+S E V L K P P Sbjct: 1510 EWVLVSNALKPQRRIVINNLQPSTLYQLRMEAHNVAGIS-QAEFNFVTLTKDGDPPPP 1566 Score = 39.1 bits (87), Expect = 1.3 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM----YYDDDNV 565 P+ + + G V +C G P PQI+W + + F + D + Sbjct: 389 PVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSNGRFMIGQYITVHGDVI 448 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAG 590 + + I V ED G + C+A+N AG Sbjct: 449 SHVNISHVMVEDGGEYACIAENRAG 473 Score = 38.3 bits (85), Expect = 2.3 Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 5/93 (5%) Query: 515 KLRPKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 +L PK T G T+ +C V GYP +I W R + P Q D ++ +++ Sbjct: 490 RLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGREL-PDDIRQRVQPDGSLTISPVQK- 547 Query: 574 FPEDAGTFTCVAKNAAGF-ASSTTELIVEAPLS 605 D+G +TC A+N G A + E+ V P S Sbjct: 548 -NSDSGVYTCWARNKQGHSARRSGEVTVIVPPS 579 Score = 36.3 bits (80), Expect = 9.2 Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 6/101 (5%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDD----D 563 +P F R G T +C V G I W R + PS ++++ D Sbjct: 770 SPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPD 829 Query: 564 NV-ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 V A L IR V D+G + C A N G +L V+ P Sbjct: 830 GVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEP 870 >UniRef50_UPI0000DA21B5 Cluster: PREDICTED: similar to hemicentin 1; n=1; Rattus norvegicus|Rep: PREDICTED: similar to hemicentin 1 - Rattus norvegicus Length = 2765 Score = 142 bits (343), Expect = 1e-31 Identities = 217/1011 (21%), Positives = 382/1011 (37%), Gaps = 94/1011 (9%) Query: 696 KITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 +I K +EG Y +AV+R G AS IV+ +PP + P ++ V GE+ I Sbjct: 388 EIPRASKAEEGVYQCIAVSRAGTGRASAQIVIT------DPPPQLVPGPNVTVSPGETAI 441 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKV-KDEGVYTLKAENS 810 LS QV+G +TW ++ +ALP K+ +++ V D G Y A N Sbjct: 442 LSCQVLGETPYNLTWVRD---WRALPVKTGRVSQLRDLSLEVSSVVPSDGGQYQCVASNP 498 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G+ S + V EP P + IN + + +++ + P P ++W R Sbjct: 499 NGLTRASTWLLVREP------PQVSINARSQ-RFSQGVEVRVSCSASGYPKPHVSWSREG 551 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 + I + G L+I V E D+G+Y C A+N G VT+ Sbjct: 552 LALPEDSRIHVDAQG---TLIIQGVAPE-DAGNYSCQAANEVGTDEE--TVTLYYTDPPS 605 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG-RXXXXXXX 987 V + T G+ +L C S + WY E+ + EG R Sbjct: 606 VSAINAVVLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVI------LAPEGSRSGTLRIP 659 Query: 988 XXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVK-EKDVAILEVEINSE 1043 D G+ C ++ ++ + ++ P QD V+ K V + Sbjct: 660 EAQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPPQDVTVELGKSVFLTCRATGRP 719 Query: 1044 TADVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEV 1100 V W R DG+ ++P + ++ + L S+ D+ Y C R+ AE Sbjct: 720 PPTVTWRRGDGQALEPGRRSRTGQRDSGV--LVFERVSLEDQAPYVCEARNVFGKAQAEA 777 Query: 1101 TVV---ELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLT 1155 +V PP+I + +V +G + + G L RW K G + N + Sbjct: 778 QLVVTGHAPPQIASSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVR 837 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPSINF----TLRLPEFI 1206 DG L + +DAG YSC N + ++ +P I P + Sbjct: 838 ADG---SLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRV 894 Query: 1207 LVPANTDAYLTVEIP-DETLDVTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 V A +A L E T VTW K ++ T ++ L+S R + + D Sbjct: 895 TVKAGEEATLDCEAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLV---QTQVGDSG 951 Query: 1265 EYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 Y C + A +T + + V+ PP++ R ++ G + L + PQP W Sbjct: 952 LYECTASNPAGATFRRYILGVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFK 1011 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP-- 1381 + ++ + S+ V+ +D G+Y ++ G ++ + +L+ P Sbjct: 1012 DGMVLMG--------EGPPGSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHW 1063 Query: 1382 SPPGKPNILE--IDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQT 1438 ++LE + ++ +C + + I + V E ++ ++V N + Sbjct: 1064 GVNETNDLLERVVGENASLLC--PAQGSPKPRITWRRVPSSEALNGRPDVAVLN--EGSL 1119 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 + ++ S + A NEV AS + + S E N++ + Sbjct: 1120 FLSSVSLADSGEYECQATNEV--GSASRRVKLVVYVP----PSIREEGRTANMSGLAGQP 1173 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + L C G P P+V W +DG+++ A A + Y C A N Sbjct: 1174 LTLECDASGFPVPEVVWLKDGQQIPEASAHRFLDGARSLHFPRIQENHSGLYSCQAENQA 1233 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + + + P + + + G + + G+P P+V W K+G L Sbjct: 1234 GRAQRDFNLAVFIPPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPL-LP 1292 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + +I +E V+RI +Y A + AG + + L ++ P+ Sbjct: 1293 GDSHILLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPT 1343 Score = 140 bits (339), Expect = 4e-31 Identities = 216/998 (21%), Positives = 371/998 (37%), Gaps = 90/998 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP S ++Q +G ++ + C P+P ++W +G + D I V + Sbjct: 513 PPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREGLALPEDSRIHVDAQ------- 565 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I V G Y+ A N G + L +PP V ++ GE Sbjct: 566 GTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYY----TDPPSVSAINAVVLTAVGEEA 621 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 +L G P P + W + V P +G + + +D G+YT KA N G Sbjct: 622 VLLCAASGVPPPRVIWYRGGLEVILAP---EGSRSGTLRIPEAQERDAGLYTCKAVNELG 678 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNE 871 A + V +PP Q++TV+ ++ L R T P P++TW R + + Sbjct: 679 DASAEIQLLVGY-APRLTDPP------QDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQ 731 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + P ++ ++ LV V E D Y C A N GK+ A++ + + Sbjct: 732 ALEPGRR-SRTGQRDSGVLVFERVSLE-DQAPYVCEARNVFGKAQAEAQLVVTGHAPPQI 789 Query: 932 KHLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 EG+ V L C +W + + + + +G Sbjct: 790 ASSASVVRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADG---SLHLDR 846 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR-KLQDFE---------VKEKDVAILEV 1038 D G C+ + S V+ + R K+ D + VK + A L+ Sbjct: 847 ALQEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDC 906 Query: 1039 EI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 E S T V W +D + P N+Y+ G +R + T V D G Y C + + Sbjct: 907 EAQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLR---LVQTQVGDSGLYECTASNPAGA 963 Query: 1098 A---EVTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQ 1153 + V++PP++ + KV G + + WFKDG + Sbjct: 964 TFRRYILGVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDG--------MV 1015 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVEEP---SINFTLRLPEFI 1206 L +G + D G Y CE +S T L V EP +N T L E + Sbjct: 1016 LMGEGPPGSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERV 1075 Query: 1207 LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 V N + + +TW + S E ++ + + +L + + D EY Sbjct: 1076 -VGENASLLCPAQGSPKP-RITWRRVPS-SEALNGRPDVAVLNEGSLFLSSVSLADSGEY 1132 Query: 1267 TCVLLDAKSTTKLKVEVVEF-PPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIV 1323 C + + +V++V + PP I + R + G +TL D FP P W+ Sbjct: 1133 ECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLK 1192 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + I + + +D + SL +++ +G+Y + EN G A + N+ + PS Sbjct: 1193 DGQQIPEASAHR-FLDG-ARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSL 1250 Query: 1384 PG---KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 G +L + + + + E + +G T VE+ + D + + Q Sbjct: 1251 LGAGAAQEVLGLAGADVKL---ECQTSGVPT---PQVEWIK-DGQPLLPGDSHILLQEDG 1303 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNE 1497 Q L+ SS+ V S A + + +++ I SP +T Sbjct: 1304 QVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQL----SIHSPPTIWGSNETGEVTVLEGH 1359 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY-ENRXXXXXXXXXXXXXXXYKCIAFND 1555 +L C G+P P +TWY+DG L +++ Y + Y C A N Sbjct: 1360 TAQLLCEARGMPAPDITWYKDGTLLAPSSEVIYSKGGRQLQLGKAQHSDAGLYTCQASNS 1419 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 G + S + + + S+ + +K + DE + T Sbjct: 1420 AGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGVYT 1457 Score = 111 bits (268), Expect = 2e-22 Identities = 174/782 (22%), Positives = 292/782 (37%), Gaps = 90/782 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 G +V C+ G P P +TW R ++P + + D V LV V ED + Sbjct: 706 GKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRDSGV--LVFERVSLEDQAPYV 763 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C A+N G A + +L+V + H +LEG P Sbjct: 764 CEARNVFGKAQAEAQLVV----TGHAPPQ-------IASSASVVRVLEGQP--------- 803 Query: 643 QYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 + L C ++A P P+ WL G + P +V + +H + Sbjct: 804 --------VSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLH-------LDRAL 848 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMIVRQGESVILSAQV 758 + G Y+ VA N G + L ++ + Q + + V+ GE L + Sbjct: 849 QEDAGRYSCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEA 908 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 G+P P +TW K+ P+ + + + + L +V D G+Y A N G Sbjct: 909 QGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRRY 968 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 ++ V+ P + P R ++ E + VA NP P + W+++ ++ Sbjct: 969 ILGVQVPPQVQPGP-----RVLKVLAGEALDLNCVAE--GNPQPQLNWFKDGMVLMG--- 1018 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 +G + V + D+G Y C AS+S+G + + + V Sbjct: 1019 -----EGPPGSVHFAAVKTS-DTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLL 1072 Query: 939 ETEEGKTVILEC--QTSHTVSTKWYH--NKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994 E G+ L C Q S W + + ++G ++ EG D Sbjct: 1073 ERVVGENASLLCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEG---SLFLSSVSLADS 1129 Query: 995 GVIKCIVKDQETSTMLVVKET--IPEFIR---KLQDFEVKEKDVAILEVEINS-ETADVV 1048 G +C ++ S VK +P IR + + LE + + +VV Sbjct: 1130 GEYECQATNEVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVV 1189 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVEL 1105 W +DG+ I P+ + + F R L+ + G YSC +++ A+ V + Sbjct: 1190 WLKDGQQI-PEASAHRF--LDGARSLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFI 1246 Query: 1106 PPEIITRLQNQKVNKGNKATFEIEL-TKG--DALVRWFKDGSE-IQFSNHIQLTIDGKKQ 1161 PP ++ Q+V A ++E T G V W KDG + +HI L DG Q Sbjct: 1247 PPSLLGAGAAQEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDG--Q 1304 Query: 1162 KLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYL 1216 L+I L D G Y C G L++ P+I + E ++ +T L Sbjct: 1305 VLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLL 1364 Query: 1217 TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST 1276 D+TWYK +++ + + +I R L + K D YTC ++ Sbjct: 1365 CEARGMPAPDITWYKDGTLLAPSSE--VIYSKGGRQLQLGKAQHSDAGLYTCQASNSAGI 1422 Query: 1277 TK 1278 TK Sbjct: 1423 TK 1424 Score = 109 bits (262), Expect = 8e-22 Identities = 189/898 (21%), Positives = 316/898 (35%), Gaps = 113/898 (12%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G T Q C+ G P P ITW++ ++ PS + + Y L + + DAG +T Sbjct: 1357 EGHTAQLLCEARGMPAPDITWYKDGTLLAPSSE--VIYSKGG-RQLQLGKAQHSDAGLYT 1413 Query: 583 CVAKNAAGFASSTT---------------ELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 C A N+AG +T +LI +A L D G T Sbjct: 1414 CQASNSAGITKKSTNLEVYGERPEGCSSGQLIEKADLRDEGV-YTCSATNLAGESKKDVT 1472 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + +PP P + V E + + LEC +P PDI+W FKG + + + + + +D Sbjct: 1473 LKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDISW-FKGRQPISTQR-HLIVSTD 1530 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIV 746 VL I + G+Y VA N G A+L L++ PP++ + P V Sbjct: 1531 GR----VLHIERAQLSDAGSYRCVATNVVGSAALQYGLRVNV----PPRITLPPSLPGPV 1582 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYT 804 G L+ G P P + W K+ PV + P + + + D G Y+ Sbjct: 1583 VLGTPFRLTCNATGTPSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYS 1642 Query: 805 LKAENSEGIAETSAVITVEEPT---------EENAEPPLFINRFQEITVKEKGTIKLVAR 855 A ++ G V+ V + PP + I+V ++ L R Sbjct: 1643 CVAVSAVGEDRRDIVLQVHSESLAWDGVCGVSIAKVPPSILGEELNISVVVNESVALECR 1702 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 P P + W ++ + P I + D +E+ +C A+ K Sbjct: 1703 SHAVPPPVLRWQKDGRPLEPHPGIRLSADKALLEVC-------------RC-AARCPEKP 1748 Query: 916 SHGARVTIDVEKVTF--VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHR 973 + RV + V++V H + G++ H W G Sbjct: 1749 NEQGRVDLWVDRVAVWDAGHYTCEAINQAGRS------EKHFNLHVW-GQPLPGDGDSQE 1801 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIPEFIRKLQDFEVK 1029 +++ GR +C QE ++V + L V Sbjct: 1802 QVLAVGRLLYLGQAQSAQEGTYTCECSNVAGTSSQEQQLEVLVPPQVTGLWEPLTTVSVI 1861 Query: 1030 EKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 + A L+ + VV WERDG+ ++ + + + + H L++ G YS Sbjct: 1862 QDGNATLDCNATGKPLPVVTWERDGQPVRMELGIW-LQNQNH--SLHVDRAQASHAGGYS 1918 Query: 1089 CILRDESCTAE---VTVVELPPEII---TRLQNQKVNKGNKATFEIELTK-GDALVRWFK 1141 C+ + + AE V PP + L N T E V+WF+ Sbjct: 1919 CVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEAEGIPPPTVQWFR 1978 Query: 1142 DGSEIQ-FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTL 1200 +G I L + QK+ D + +L EE + Sbjct: 1979 EGQPISPGEGTYLLAVPPMFQKMGDADAGFE----------------LLPHEEEAQG--- 2019 Query: 1201 RLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 R+ E+ V N AYL T IP ++TWY++ + + +++ R L + Sbjct: 2020 RVTEYREVVENNPAYLYCDTNAIPPP--ELTWYREGQPLSAVDGVSVLQG--GRILQLPL 2075 Query: 1258 CTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-----DYEREYRIKRGSDVTLLVDYQ 1312 +D Y+C + L E++ P ++ + E + S V+L Sbjct: 2076 VQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPAL 2135 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 P P W N + + + + L + E TDA Y EN G A+ Sbjct: 2136 GNPAPALSWFQNGLPVSPSPRLQ--VLEEGQVLKVSTAEVTDAANYMCVAENQAGSAE 2191 Score = 108 bits (260), Expect = 1e-21 Identities = 172/794 (21%), Positives = 291/794 (36%), Gaps = 63/794 (7%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +L G P + P+ V+ G + L CR P P + W + + S + D Sbjct: 686 LLVGYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRRSRTGQRD 745 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 VL V + Y A N G+A L + TG PPQ+ + V Sbjct: 746 ----SGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQL-VVTGH-APPQIASSASVVRVL 799 Query: 748 QGESVILSAQVV-GNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803 +G+ V L+ ++ G P P W K +P+ ++DG H L+ +D G Y Sbjct: 800 EGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADGSLHLDRALQ----EDAGRY 855 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + A N G + V+ + +TVK L +P P Sbjct: 856 SCVATNVAGSQHRDVELVVQAKPRIKINDSQATDAPLRVTVKAGEEATLDCEAQGSPTPL 915 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +TW ++ + P + ++ LV T V DSG Y+C ASN AG + R + Sbjct: 916 VTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVG---DSGLYECTASNPAGATFR--RYIL 970 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981 V+ V+ + + G+ + L C + + W+ + + G EG Sbjct: 971 GVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMG--------EGPP 1022 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQE-TSTMLVVKETI--PEF-IRKLQDF--EVKEKDVAI 1035 D G+ C T T + + + P + + + D V ++ ++ Sbjct: 1023 GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERVVGENASL 1082 Query: 1036 LEVEINSETADVVWER--DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 L S + W R E + + + + L++ + S+ D GEY C + Sbjct: 1083 LCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNE----GSLFLSSVSLADSGEYECQATN 1138 Query: 1094 E--SCTAEV-TVVELPPEIIT--RLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQ 1147 E S + V VV +PP I R N G T E + + V W KDG +I Sbjct: 1139 EVGSASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLECDASGFPVPEVVWLKDGQQIP 1198 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLP 1203 ++ + +DG + L + +G YSC+ N A L V P Sbjct: 1199 EASAHRF-LDGAR-SLHFPRIQENHSGLYSCQAENQAGRAQRDFNLAVFIPPSLLGAGAA 1256 Query: 1204 EFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDD 1262 + +L A D L + T V W K + + L+ + + L I D Sbjct: 1257 QEVLGLAGADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQE-DGQVLRIISSHLGD 1315 Query: 1263 QCEYTCVLLDAKSTTKLKVEV-VEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPND 1319 + Y CV ++ + PP I + E + G LL + + P P+ Sbjct: 1316 EGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDI 1375 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 W + ++ I SK L + K +++DAG+Y + N+ G N+ + Sbjct: 1376 TWYKDGTLLAPSSEV---IYSKGGRQLQLGKAQHSDAGLYTCQASNSAGITKKSTNLEVY 1432 Query: 1379 -DKPSPPGKPNILE 1391 ++P ++E Sbjct: 1433 GERPEGCSSGQLIE 1446 Score = 99 bits (238), Expect = 7e-19 Identities = 158/816 (19%), Positives = 295/816 (36%), Gaps = 57/816 (6%) Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SH 954 S+ + G Y+C+A + AG A++ I V + G+T IL CQ Sbjct: 393 SKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPG--PNVTVSPGETAILSCQVLGET 450 Query: 955 TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTML 1010 + W + + + R + + R D G +C+ + ST L Sbjct: 451 PYNLTWVRDWRALPVKTGR--VSQLRDLSLEVSSVVPSDGGQYQCVASNPNGLTRASTWL 508 Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH 1070 +V+E I + +V + V W R+G + P+ ++ + +G Sbjct: 509 LVREPPQVSINARSQRFSQGVEVRVSCSASGYPKPHVSWSREG-LALPEDSRIHVDAQG- 566 Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITRLQNQKVNKGNKATFEI 1128 L I+ + D G YSC +E T E VT+ P ++ + + + + Sbjct: 567 --TLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAINAVVLTAVGEEAVLL 624 Query: 1129 ELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 G V W++ G E+ I + L+I + DAG Y+C+ N Sbjct: 625 CAASGVPPPRVIWYRGGLEV-----ILAPEGSRSGTLRIPEAQERDAGLYTCKAVNELGD 679 Query: 1187 AILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKF 1242 A ++ + + RL P+ + V +LT VTW + + + Sbjct: 680 ASAEIQL-LVGYAPRLTDPPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRR 738 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRI 1299 + L+ + + +DQ Y C + + + ++V PP+I R+ Sbjct: 739 SRTGQRDSGVLVFERVSLEDQAPYVCEARNVFGKAQAEAQLVVTGHAPPQIASSASVVRV 798 Query: 1300 KRGSDVTLL-VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 G V+L V P P W+ + + D SL + + DAG Y Sbjct: 799 LEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRADG---SLHLDRALQEDAGRY 855 Query: 1359 KLRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 N G H DVE+ V KP I DS + + G + Sbjct: 856 SCVATNVAGSQHRDVELVVQ--------AKPRIKINDSQATDAPLRVTVKAGEEATLDCE 907 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE----YYK 1472 + W + T+ L ++ S R V + + + + + + + Sbjct: 908 AQGSPTPLVTWTKDAHPLLPVTNRYELLSSGSLRLVQTQVGDSGLYECTASNPAGATFRR 967 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 I ++ P V+ + + E ++L C+ G PQP++ W++DG L Sbjct: 968 YILGVQVP-PQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMVLMGEGPP---- 1022 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C A + G + + + P ++ + + VG+ + Sbjct: 1023 GSVHFAAVKTSDTGLYHCEASSSSGTDTWKLELQVLEPPHWGVNETNDLLERVVGENASL 1082 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 +G P P + W + + + ++ + S+ + + + S +Y +A+N G Sbjct: 1083 LCPAQGSPKPRITWRRVPSSEALNGRPDVAVLNEGSLF-LSSVSLADSGEYECQATNEVG 1141 Query: 1653 TSSVEVTLKVYDKPS-KPEGPVI-MREISRESVTIE 1686 ++S V L VY PS + EG M ++ + +T+E Sbjct: 1142 SASRRVKLVVYVPPSIREEGRTANMSGLAGQPLTLE 1177 Score = 87.0 bits (206), Expect = 5e-15 Identities = 105/490 (21%), Positives = 200/490 (40%), Gaps = 64/490 (13%) Query: 489 NEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 ++K+ +L V P+ ++ P ++R G C+ + P P +TWF+ Sbjct: 2228 DQKMVQLSVLVPPSFKQAPGGPQEAVQVRA-----GDKATLNCETDSLPEPAVTWFKDQQ 2282 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHG 608 + Q Q L I + D G ++C N AG A+ T EL ++ + + Sbjct: 2283 PLALGQRIQGLQGGQK---LEILDSQVSDKGVYSCKVSNTAGEATRTFELNIQGSVWGYS 2339 Query: 609 SEMTVXXXXXXXXXXXXADILEG-----------------IPPTFSKKPKAQY--VDEGS 649 + V L +PP Q V EG Sbjct: 2340 TCQLVNPVALSAESYPMLASLPPASACPCCFRAFTMAPVTVPPQIQNSGMTQEHNVLEGQ 2399 Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 ++ L C P PDIAWL +G + D+++ + ++ S L + ++ G YT Sbjct: 2400 EVRLGCEAEGQPPPDIAWLKEGGPL--DQHVGPHLR--FYLDGSTLVLKGLRAADSGAYT 2455 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 VA N GE + + + Q + +++ R GE V + V G+P ++W Sbjct: 2456 CVAHNPAGEDARLHTVNVLVPPTIKQQASD-TGTLVSRTGELVTMMCPVQGSPPIHVSWL 2514 Query: 770 KNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT-- 826 K+ P+ AL ++ T+ + ++ D GV+T A + G+A + + V++ + Sbjct: 2515 KDGLPL-ALSQRTLLHNSGRTLRISQVQLADSGVFTCVASSPAGVANRNFTLLVDKGSVL 2573 Query: 827 EENAE-------------------PPLF-INRFQEITVKEKGT-IKLVARVTRNPVPSIT 865 E++ PP+ FQ + +G+ + L +P+P ++ Sbjct: 2574 EDSPSVRVPKALSMRATDCAKIQVPPILEPEEFQNDVMAAQGSEVVLPCEARGSPLPLVS 2633 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W ++ E + P +++ Q G ++L ++ DSG Y C+A++ AG++ ++T+ Sbjct: 2634 WMKDGEPLLP-QSLEQ---GPGLKLEAVSIG---DSGTYSCMAASEAGEARRHFQLTVME 2686 Query: 926 EKVTFVKHLQ 935 +T HL+ Sbjct: 2687 LSLTPGAHLE 2696 Score = 85.8 bits (203), Expect = 1e-14 Identities = 92/422 (21%), Positives = 163/422 (38%), Gaps = 33/422 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V+ ECQ G P PQ+ W + + P + +D V ++ + D G + C Sbjct: 1264 GADVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDGQVLRIISSHL--GDEGRYQC 1321 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP-PTFSKKPKA 642 VA + AG + +L + +P + GS T G+P P + Sbjct: 1322 VAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKDG 1381 Query: 643 QYVDEGSDILL-----ECRLVAIPEPDIAWLF----KGEEIVPDENISVAIESDMHMYCS 693 + S+++ + +L D A L+ + ++ ++ + + CS Sbjct: 1382 TLLAPSSEVIYSKGGRQLQLGKAQHSD-AGLYTCQASNSAGITKKSTNLEVYGERPEGCS 1440 Query: 694 VLKITNVKKFQ-EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 ++ + EG YT A N GE+ + LK+ PP + + V + SV Sbjct: 1441 SGQLIEKADLRDEGVYTCSATNLAGESKKDVTLKVLV----PPNIEPGPVNKAVLENASV 1496 Query: 753 ILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L G P P I+W K +P+ + L +DG + ++ ++ D G Y A N Sbjct: 1497 TLECLASGVPPPDISWFKGRQPISTQRHLIVSTDG---RVLHIERAQLSDAGSYRCVATN 1553 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G A + V P P L V +L T P P + W ++ Sbjct: 1554 VVGSAALQYGLRVNVPPRITLPPSL------PGPVVLGTPFRLTCNATGTPSPMLLWLKD 1607 Query: 870 NEIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 +SP T + F G + L + + + D+G Y CVA ++ G+ + + E + Sbjct: 1608 GNPVSPEGTPGLKVFPGGQV-LTVASARAS-DAGGYSCVAVSAVGEDRRDIVLQVHSESL 1665 Query: 929 TF 930 + Sbjct: 1666 AW 1667 Score = 77.0 bits (181), Expect = 5e-12 Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 7/177 (3%) Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFN 1554 D++L C GVP P+V W +DG+ L + E+ Y+C+AF+ Sbjct: 1266 DVKLECQTSGVPTPQVEWIKDGQPLLPGDSHILLQEDGQVLRIISSHLGDEGRYQCVAFS 1325 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 G+ + I P I SNE + G + G+P P++ WYK+G L Sbjct: 1326 PAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEARGMPAPDITWYKDGTLLA 1385 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 E + + +++ + + S + YT +ASN+AG + L+VY + +PEG Sbjct: 1386 PSSE--VIYSKGGRQLQLGKAQHSDAGLYTCQASNSAGITKKSTNLEVYGE--RPEG 1438 Score = 72.9 bits (171), Expect = 9e-11 Identities = 71/338 (21%), Positives = 139/338 (41%), Gaps = 24/338 (7%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP--PGKPNI-LEIDSS 1395 +S ++S I + + G+Y+ + G + I D P PG PN+ + + Sbjct: 381 ESGNSSWEIPRASKAEEGVYQCIAVSRAGTGRASAQIVITDPPPQLVPG-PNVTVSPGET 439 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 +I C E N T +V +++ + V + + ++ + +++ A Sbjct: 440 AILSCQVLGETPYNLT---WVRDWRALPVKTG-RVSQLRDLSLEVSSVVPSDGGQYQCVA 495 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 N ++ AS + +++E P V ++ ++ ++C G P+P V+W Sbjct: 496 SNPNGLTRAST----WLLVREP----PQVSINARSQRFSQGVEVRVSCSASGYPKPHVSW 547 Query: 1516 YRDGKKL-KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 R+G L + ++ + + Y C A N+ G E + + P ++ Sbjct: 548 SREGLALPEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVS 607 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 N + VG+E ++ G+PPP VIWY+ G ++ E ++ +RI E Sbjct: 608 AINAVVLTA--VGEEAVLLCAASGVPPPRVIWYRGGLEVILAPE-----GSRSGTLRIPE 660 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + + YT +A N G +S E+ L V P + P Sbjct: 661 AQERDAGLYTCKAVNELGDASAEIQLLVGYAPRLTDPP 698 Score = 66.5 bits (155), Expect = 8e-09 Identities = 47/179 (26%), Positives = 75/179 (41%), Gaps = 6/179 (3%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V E + L C AIP P++ W +G+ + + +SV +L++ V+ Sbjct: 2027 VVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGG------RILQLPLVQAED 2080 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y+ A N GE L L + T P E ++ + V +V L +GNP P Sbjct: 2081 AGRYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAP 2140 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 ++W +N PV P + + + +V D Y AEN G AE + V+ Sbjct: 2141 ALSWFQNGLPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQ 2199 Score = 60.9 bits (141), Expect = 4e-07 Identities = 69/304 (22%), Positives = 116/304 (38%), Gaps = 19/304 (6%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C P P++TW+R+ + + D + L + V EDAG ++C A N G Sbjct: 2037 CDTNAIPPPELTWYREGQPLS-AVDGVSVLQGGRILQLPL--VQAEDAGRYSCKASNEVG 2093 Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 EL+V P G T A LE P + P + G Sbjct: 2094 EDWLHYELLVLTPPVIPGD--TQELVEEVTVNASSAVSLE-CPALGNPAPALSWFQNGLP 2150 Query: 651 ILLECRLVAIPEPDIAWLFKGEE------IVPDENISVAIESDMHMYCS---VLKITNVK 701 + RL + E + + E + EN + + E + L++ + Sbjct: 2151 VSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQGTHTLRLARAQ 2210 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 GTY A+N G + L + P +++ VR G+ L+ + Sbjct: 2211 PADSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPGGPQEAVQVRAGDKATLNCETDSL 2270 Query: 762 PRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P P +TW K+ +P+ AL + G + IL +V D+GVY+ K N+ G A + Sbjct: 2271 PEPAVTWFKDQQPL-ALGQRIQGLQGGQKLEIL-DSQVSDKGVYSCKVSNTAGEATRTFE 2328 Query: 820 ITVE 823 + ++ Sbjct: 2329 LNIQ 2332 Score = 57.6 bits (133), Expect = 4e-06 Identities = 36/186 (19%), Positives = 73/186 (39%), Gaps = 3/186 (1%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXX 1539 P +E N N + L C+ GVP P ++W++ + + T + + Sbjct: 1479 PNIEPGPVNKAVLENASVTLECLASGVPPPDISWFKGRQPISTQRHLIVSTDGRVLHIER 1538 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y+C+A N G + + P IT+ + +G + +T G Sbjct: 1539 AQLSDAGSYRCVATNVVGSAALQYGLRVNVPPRITLP-PSLPGPVVLGTPFRLTCNATGT 1597 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P ++W K+GN + + + V+ + + S + Y+ A + G ++ Sbjct: 1598 PSPMLLWLKDGNPVSPEGTPGLKVFPGGQVLTVASARASDAGGYSCVAVSAVGEDRRDIV 1657 Query: 1660 LKVYDK 1665 L+V+ + Sbjct: 1658 LQVHSE 1663 Score = 56.4 bits (130), Expect = 8e-06 Identities = 53/217 (24%), Positives = 87/217 (40%), Gaps = 23/217 (10%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S V EC G P P ++WF+ + PS Q+ ++ V + EV DA + CV Sbjct: 2126 SAVSLECPALGNPAPALSWFQNGLPVSPSPRLQV-LEEGQVLKVSTAEV--TDAANYMCV 2182 Query: 585 AKNAAGFASSTTELIVE---------APLSDHGSEMTVXXXXXXXXXXXXADILEGIPPT 635 A+N AG A L V+ A +D G+ + + +PP+ Sbjct: 2183 AENQAGSAEKLFTLRVQGTHTLRLARAQPADSGTYL-CEALNPAGRDQKMVQLSVLVPPS 2241 Query: 636 FSKKP----KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 F + P +A V G L C ++PEP + W + + + I ++ Sbjct: 2242 FKQAPGGPQEAVQVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQ-GLQGGQK-- 2298 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 L+I + + +G Y+ N GEA+ L I+ Sbjct: 2299 ---LEILDSQVSDKGVYSCKVSNTAGEATRTFELNIQ 2332 Score = 55.6 bits (128), Expect = 1e-05 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 4/89 (4%) Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576 R + G V+ C GYP+P ++W R+ + +D +++ D TL+I+ V PE Sbjct: 521 RSQRFSQGVEVRVSCSASGYPKPHVSWSREGLALP--EDSRIHVDAQG--TLIIQGVAPE 576 Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLS 605 DAG ++C A N G T L P S Sbjct: 577 DAGNYSCQAANEVGTDEETVTLYYTDPPS 605 Score = 52.4 bits (120), Expect = 1e-04 Identities = 39/171 (22%), Positives = 70/171 (40%), Gaps = 6/171 (3%) Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAF 1553 N L C +P P++TWYR+G+ L + + Y C A Sbjct: 2030 NNPAYLYCDTNAIPPPELTWYREGQPLSAVDGVSVLQGGRILQLPLVQAEDAGRYSCKAS 2089 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE--GIPPPEVIWYKNGN 1611 N+ GE + + PVI +++ ++ V V+ G P P + W++NG Sbjct: 2090 NEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPALSWFQNG- 2148 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 L + E+ V+++ + + ++ Y A N AG++ TL+V Sbjct: 2149 -LPVSPSPRLQVLEEGQVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRV 2198 Score = 52.0 bits (119), Expect = 2e-04 Identities = 43/176 (24%), Positives = 70/176 (39%), Gaps = 8/176 (4%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXXXXXXXXXYKCIA 1552 +++ L C G P P + W ++G L Y + Y C+A Sbjct: 2399 QEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVLKGLRAADSGAYTCVA 2458 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDI-KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N GE V + P I D + G+ + ++G PP V W K+G Sbjct: 2459 HNPAGEDARLHTVNVLVPPTIKQQASDTGTLVSRTGELVTMMCPVQGSPPIHVSWLKDGL 2518 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 L + + +T +RI +++ + S +T AS+ AG ++ TL V DK S Sbjct: 2519 PLALSQRTLLHNSGRT--LRISQVQLADSGVFTCVASSPAGVANRNFTLLV-DKGS 2571 Score = 50.4 bits (115), Expect = 5e-04 Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 3/131 (2%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXX 1543 +PL ++ + + L C G P P VTW RDG+ ++ + Sbjct: 1853 EPLTTVSVIQDGNATLDCNATGKPLPVVTWERDGQPVRMELGIWLQNQNHSLHVDRAQAS 1912 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPP 1602 Y C+A N G E + + P +T ++ + + + EGIPPP Sbjct: 1913 HAGGYSCVAENIAGRAERRFALSVLAPPHLTGDSDSLTNVTATLHGSLTLLCEAEGIPPP 1972 Query: 1603 EVIWYKNGNKL 1613 V W++ G + Sbjct: 1973 TVQWFREGQPI 1983 Score = 46.8 bits (106), Expect = 0.007 Identities = 29/77 (37%), Positives = 37/77 (48%), Gaps = 3/77 (3%) Query: 1117 KVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 +V G+KAT E + V WFKD + IQ G QKL+I D + D G Sbjct: 2254 QVRAGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGG--QKLEILDSQVSDKGV 2311 Query: 1176 YSCEVGNSKCTAILTVE 1192 YSC+V N+ A T E Sbjct: 2312 YSCKVSNTAGEATRTFE 2328 Score = 46.8 bits (106), Expect = 0.007 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 1575 ISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I N + Q+H V G E + EG PPP++ W K G L+ ++ S + + Sbjct: 2384 IQNSGMTQEHNVLEGQEVRLGCEAEGQPPPDIAWLKEGGPLDQHVGPHLRFYLDGSTLVL 2443 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 K L+ + S YT A N AG + T+ V P+ Sbjct: 2444 KGLRAADSGAYTCVAHNPAGEDARLHTVNVLVPPT 2478 Score = 44.0 bits (99), Expect = 0.046 Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 7/138 (5%) Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 TH++ + + + D G Y +A N G + ++V P P + + V+ Sbjct: 2201 THTLRLARAQPA-DSGTYLCEALNPAGRDQKMVQLSVLVPPSFKQAPG---GPQEAVQVR 2256 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 L P P++TW+++ + ++ + I G+ +E++ + V D G Y Sbjct: 2257 AGDKATLNCETDSLPEPAVTWFKDQQPLALGQRIQGLQGGQKLEILDSQVS---DKGVYS 2313 Query: 906 CVASNSAGKSSHGARVTI 923 C SN+AG+++ + I Sbjct: 2314 CKVSNTAGEATRTFELNI 2331 Score = 40.7 bits (91), Expect = 0.43 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 12/97 (12%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 T G C G P P++ W+R I+ P + TL I E DA Sbjct: 615 TAVGEEAVLLCAASGVPPPRVIWYRGGLEVILAP--------EGSRSGTLRIPEAQERDA 666 Query: 579 GTFTCVAKNAAGFASSTTELIV-EAP-LSDHGSEMTV 613 G +TC A N G AS+ +L+V AP L+D ++TV Sbjct: 667 GLYTCKAVNELGDASAEIQLLVGYAPRLTDPPQDVTV 703 Score = 40.7 bits (91), Expect = 0.43 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 5/81 (6%) Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G V C + G P P+ W + + P + D +L + EDAG + Sbjct: 800 EGQPVSLTCVILAGRPLPERRWLKAGRPLPPGNRHAVRAD----GSLHLDRALQEDAGRY 855 Query: 582 TCVAKNAAGFASSTTELIVEA 602 +CVA N AG EL+V+A Sbjct: 856 SCVATNVAGSQHRDVELVVQA 876 Score = 40.3 bits (90), Expect = 0.57 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T CQV G +TW R + P + ++ D +L + V P D G + C Sbjct: 437 GETAILSCQVLGETPYNLTWVRDWRAL-PVKTGRVSQLRD--LSLEVSSVVPSDGGQYQC 493 Query: 584 VAKNAAGFASSTTELIVEAP 603 VA N G ++T L+V P Sbjct: 494 VASNPNGLTRASTWLLVREP 513 Score = 39.1 bits (87), Expect = 1.3 Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 19/201 (9%) Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 EV E + A L + N+ ++ W R+G+ + + G I +L + D G Sbjct: 2026 EVVENNPAYLYCDTNAIPPPELTWYREGQPLSAVDG-VSVLQGGRILQLPL--VQAEDAG 2082 Query: 1086 EYSCILRDE--SCTAEVTVVELPPEIITR-----LQNQKVNKGNKATFEIELTKGDA-LV 1137 YSC +E ++ L P +I ++ VN + + E A + Sbjct: 2083 RYSCKASNEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAL 2142 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA--ILTVEEPS 1195 WF++G + S +Q+ +G Q LK+ ++ DA Y C N +A + T+ Sbjct: 2143 SWFQNGLPVSPSPRLQVLEEG--QVLKVSTAEVTDAANYMCVAENQAGSAEKLFTLRVQG 2200 Query: 1196 INFTLRLPEFILVPANTDAYL 1216 + TLRL PA++ YL Sbjct: 2201 TH-TLRLAR--AQPADSGTYL 2218 Score = 38.3 bits (85), Expect = 2.3 Identities = 20/44 (45%), Positives = 25/44 (56%) Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 YT A+N AG S +VTLKV P+ GPV + SVT+E Sbjct: 1456 YTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKAVLENASVTLE 1499 Score = 37.5 bits (83), Expect = 4.0 Identities = 14/42 (33%), Positives = 23/42 (54%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 L N+T + + L C G+P P V W+R+G+ + + TY Sbjct: 1949 LTNVTATLHGSLTLLCEAEGIPPPTVQWFREGQPISPGEGTY 1990 >UniRef50_A7RGL8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 578 Score = 141 bits (342), Expect = 2e-31 Identities = 151/578 (26%), Positives = 247/578 (42%), Gaps = 65/578 (11%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMH 689 G P+ S + V EG+DI L C++ P+P + W +KG+ +V D+ IS + Sbjct: 12 GDAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTW-YKGDALVKLDDRISAHFDGRF- 69 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S L I K EG Y N G+A + L ++ +P V E + V +G Sbjct: 70 ---SRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERG 126 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 E V +V G P+P + W + PV +DG SI+ + E +Y+L Sbjct: 127 E-VRFEVRVTGFPKPRVEWYRG--PVHL----TDGGRFSIS-------EKEDMYSL---- 168 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 TV + +++ + + TV + LV RV+ P P+ITW+R+ Sbjct: 169 -----------TVRDLKRDDSGTYKLV---AQNTVGKCDKYTLVCRVSGKPKPTITWFRD 214 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV- 928 N + + +++G L + + D+G YKC A+NS G +S A VTI + Sbjct: 215 NTPVHTDNRVVASYEGSVSALELKEMKLS-DAGLYKCTATNSQGSTSSSAEVTIKRKDAI 273 Query: 929 -TFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 TFV L K E E + L+ + + ++Y + I + +I+++G Sbjct: 274 PTFVVGL-KETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLI 332 Query: 986 XXXXXXXDVGVIKCIVKD---QETSTMLV-VKE--------TIPEFIRKLQDFEVKEKDV 1033 D G KC++ + ETS ++ V+E PEF+RK++D E + Sbjct: 333 ITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQ 392 Query: 1034 AILEVEINSETADVV-WERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 E+ I +V W R IK + + + L I D G Y C+ Sbjct: 393 VWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVA 452 Query: 1092 RDES--CTA----EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144 +++ TA +V + PE ++ +V G +AT +E+ K V W+KDG Sbjct: 453 SNDAGKTTALLNLDVNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGK 512 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 ++ S +IQL G ++I +D G Y CE N Sbjct: 513 VLRESKNIQLKSIGDTYSIRIVRTAPEDVGTYMCEATN 550 Score = 120 bits (288), Expect = 6e-25 Identities = 99/403 (24%), Positives = 170/403 (42%), Gaps = 48/403 (11%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+V G P+P ITWFR + Y+ +V+ L ++E+ DAG + C A N+ G Sbjct: 199 CRVSGKPKPTITWFRDNTPVHTDNRVVASYEG-SVSALELKEMKLSDAGLYKCTATNSQG 257 Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 SS+ +E+T+ PTF K E SD Sbjct: 258 STSSS-------------AEVTIKRKDAI--------------PTFVVGLKETEGLESSD 290 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + L+ ++ P P + + + IV E + + D CS++ ITN++ GTY Sbjct: 291 MRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDR---CSLI-ITNLRPEDAGTYKC 346 Query: 711 VAVNREGEASLPIVLKIKTGEKEP-----PQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 V N G + V++++ E P P+ + ++ + + E V + G PRP Sbjct: 347 VITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPI 406 Query: 766 ITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W + +K + + D +S+ ++ + +D G Y A N G +T+A++ Sbjct: 407 VEWYRGTTRIKDGGRFTISESEENDMYSL-VIDEARTEDSGPYKCVASNDAG--KTTALL 463 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 ++ E P F + I VK + P P +TWY++ +++ S+ I Sbjct: 464 NLD--VNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQ 521 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 G+ + I E D G Y C A+N AG +S +TI Sbjct: 522 LKSIGDTYSIRIVRTAPE-DVGTYMCEATNKAGLASRKFDITI 563 Score = 113 bits (272), Expect = 5e-23 Identities = 129/577 (22%), Positives = 236/577 (40%), Gaps = 56/577 (9%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 + P ++ + V E I LV +V+ NP P++TWY+ + ++ + I+ +FDG L Sbjct: 13 DAPSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRL 72 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT--FVKHLQKSYETEEGKTVIL 948 I + D G Y C N GK+ +T+ V V ++ + E E G+ V Sbjct: 73 SIQKATKD-DEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGE-VRF 130 Query: 949 ECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET 1006 E + + + WY G H + GR V +K +D Sbjct: 131 EVRVTGFPKPRVEWYR------GPVH--LTDGGRFSISEKEDMYSLTVRDLK---RDDSG 179 Query: 1007 STMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFE 1066 + LV + T+ + +K + V + W RD + N+ Sbjct: 180 TYKLVAQNTVGKC----------DKYTLVCRVS-GKPKPTITWFRDNTPVHTD-NRVVAS 227 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVV--ELPPEIITRLQNQKVNK 1120 G + L ++ + D G Y C + S +AEVT+ + P + L+ + + Sbjct: 228 YEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLE 287 Query: 1121 GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 + ++++ V ++KD I S ++ DG + L I + +DAG Y C Sbjct: 288 SSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCV 347 Query: 1180 VGN----SKCTAILTVEEP--SINFTLRLPEFILVPANTDAYLT----VEIPDETLD--- 1226 + N A++ V+E + F ++ PEF+ + A T EIP + Sbjct: 348 ITNLLGVETSEAVIRVQEREHAPRFDVK-PEFLRKVEDVTALETEQVWFEIPIQGYPRPI 406 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVE 1282 V WY+ + I+D +FT+ + +L+I + +D Y CV + K+T L ++ Sbjct: 407 VEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLD 466 Query: 1283 VVE--FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V E P+ + +K G + T ++ + P+P W + K++++ K+ + Sbjct: 467 VNEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIG 526 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + S+ I + D G Y N G A + ++TI Sbjct: 527 DTYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITI 563 Score = 110 bits (264), Expect = 5e-22 Identities = 87/329 (26%), Positives = 149/329 (45%), Gaps = 37/329 (11%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T + + P FV L+ + S ++ + ++ G+PRP + +++ +I S+ ++ D Sbjct: 266 TIKRKDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILED 325 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 D +L+I + PEDAGT+ CV N G T+E ++ +H V Sbjct: 326 GDR-CSLIITNLRPEDAGTYKCVITNLLGV--ETSEAVIRVQEREHAPRFDVK------- 375 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN-- 679 P F +K + E + E + P P + W ++G + D Sbjct: 376 ------------PEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEW-YRGTTRIKDGGRF 422 Query: 680 -ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE-PPQV 737 IS + E+DM+ L I + G Y VA N G+ + +L + EK P+ Sbjct: 423 TISESEENDMYS----LVIDEARTEDSGPYKCVASNDAGKTTA--LLNLDVNEKVVQPEF 476 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794 + +K + V+ GE S ++ G P+P +TW K+ K + K + KS GDT+SI I++ Sbjct: 477 DKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGDTYSIRIVRT 536 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVE 823 +D G Y +A N G+A IT++ Sbjct: 537 AP-EDVGTYMCEATNKAGLASRKFDITIK 564 Score = 105 bits (253), Expect = 1e-20 Identities = 118/577 (20%), Positives = 224/577 (38%), Gaps = 49/577 (8%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + ++L +V +GN +++ V W+K + ++ + I DG+ +L I Sbjct: 15 PSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRLSI 74 Query: 1166 YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 DD G Y C+V N A VE ++ P+ + + + E+ E Sbjct: 75 QKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVK-PQIVGEIKDAEEVERGEVRFEVR 133 Query: 1226 -------DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 V WY+ + D +F++ +L +R DD Y V A++T Sbjct: 134 VTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLV---AQNT-- 188 Query: 1279 LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 + + TL+ P+P W ++ + S Sbjct: 189 --------------------VGKCDKYTLVCRVSGKPKPTITWFRDNTPVHTDNRVVASY 228 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP----GKPNILEIDS 1394 + ++L +K+++ +DAG+YK N+ G VTI K + P G ++S Sbjct: 229 EGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVGLKETEGLES 288 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 S + + + T+ +Y +D+ +++ + I NL+ + ++ Sbjct: 289 SDMRLDV-KIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPEDAGTYKCV 347 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 N + + + + + P + ++++T E + G P+P V Sbjct: 348 ITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIV 407 Query: 1514 TWYR------DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 WYR DG + +++ + YKC+A ND G+ + + Sbjct: 408 EWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 467 Query: 1568 QQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 +K V ++++K + K G+E + I+G P P+V WYK+G L K + + Sbjct: 468 NEKVVQPEFDKEVKPIEVKHGEEATTSLEIKGKPKPKVTWYKDGKVLRESKNIQLKSIGD 527 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSS--VEVTLK 1661 T IRI Y EA+N AG +S ++T+K Sbjct: 528 TYSIRIVRTAPEDVGTYMCEATNKAGLASRKFDITIK 564 Score = 92.7 bits (220), Expect = 1e-16 Identities = 107/462 (23%), Positives = 189/462 (40%), Gaps = 50/462 (10%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE 1282 VTWYK ++++ ++ + D + L I+K T+DD+ Y C + + A S +L V Sbjct: 46 VTWYKGDALVKLDDRISAHFDGRFSRLSIQKATKDDEGIYICDVQNELGKAFSKVELTVR 105 Query: 1283 VVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 P+IV + + ++RG +V V FP+P EW + S Sbjct: 106 KRNVKPQIVGEIKDAEEVERG-EVRFEVRVTGFPKPRVEWYRGPVHLTDGGRFSISEKED 164 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 SLT++ ++ D+G YKL +N G D T++ + S KP I ++ Sbjct: 165 MYSLTVRDLKRDDSGTYKLVAQNTVGKCD---KYTLVCRVSGKPKPTITWFRDNT----- 216 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 P +T N + Y ++ E +K + + ++ A N Sbjct: 217 --PVHTDNRVVASYEGSVSALELKE----------------MKLSDAGLYKCTATN---- 254 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 S S ++ IK K PT LK + D+ L GG P+P V +Y+D Sbjct: 255 SQGSTSSSAEVTIKR-KDAIPTFVVGLKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDL 313 Query: 1522 LKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVIT 1574 + ++ +R YKC+ N G + V+ +Q++ P Sbjct: 314 IVDSERHKILEDGDRCSLIITNLRPEDAGTYKCVITNLLGVETSEAVIRVQEREHAPRFD 373 Query: 1575 ISNEDIKQKHKVG----DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV- 1629 + E +++ V ++ I+G P P V WY+ ++++ + I+ E+ + Sbjct: 374 VKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRFTISESEENDMY 433 Query: 1630 -IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 + I E + S Y ASN AG ++ + L V +K +PE Sbjct: 434 SLVIDEARTEDSGPYKCVASNDAGKTTALLNLDVNEKVVQPE 475 Score = 63.7 bits (148), Expect = 5e-08 Identities = 48/195 (24%), Positives = 81/195 (41%), Gaps = 7/195 (3%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXX 1537 +P++ L + DI+L C P+P VTWY+ +K A ++ R Sbjct: 14 APSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHFDGRFSRLS 73 Query: 1538 XXXXXXXXXX-YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG-DEWLVTAV 1595 Y C N+ G+ + + ++++ V +IK +V E Sbjct: 74 IQKATKDDEGIYICDVQNELGKAFSKVELTVRKRNVKPQIVGEIKDAEEVERGEVRFEVR 133 Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG-TS 1654 + G P P V WY+ L + ++I+ KE + +++LKR S Y + A NT G Sbjct: 134 VTGFPKPRVEWYRGPVHLTDGGRFSISEKEDMYSLTVRDLKRDDSGTYKLVAQNTVGKCD 193 Query: 1655 SVEVTLKVYDKPSKP 1669 + +V KP KP Sbjct: 194 KYTLVCRVSGKP-KP 207 Score = 63.7 bits (148), Expect = 5e-08 Identities = 61/303 (20%), Positives = 117/303 (38%), Gaps = 14/303 (4%) Query: 1465 SETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 SE + Y + +++ K K + T + L C G P+P +TW+RD + Sbjct: 160 SEKEDMYSLTVRDLKRDDSGTYKLVAQNTVGKCDKYTLVCRVSGKPKPTITWFRDNTPVH 219 Query: 1524 T---AKATYENR-XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 T A+YE YKC A N G +S V I++K I Sbjct: 220 TDNRVVASYEGSVSALELKEMKLSDAGLYKCTATNSQGSTSSSAEVTIKRKDAIPTFVVG 279 Query: 1580 IKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRS 1638 +K+ + + + I G P P V +YK+ + + + + + I + I L+ Sbjct: 280 LKETEGLESSDMRLDVKIGGFPRPTVEFYKDYDLIVDSERHKILEDGDRCSLIITNLRPE 339 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE---GPVIMREI----SRESVTIEWKPPL 1691 + Y +N G + E ++V ++ P P +R++ + E+ + ++ P+ Sbjct: 340 DAGTYKCVITNLLGVETSEAVIRVQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPI 399 Query: 1692 DDGGLELTK-YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 + + Y D R+ + D+ + I + ++ +A N G + Sbjct: 400 QGYPRPIVEWYRGTTRIKDGGRFTISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKT 459 Query: 1751 EAL 1753 AL Sbjct: 460 TAL 462 Score = 62.1 bits (144), Expect = 2e-07 Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 1/105 (0%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 V E+ + + P F+ K+ + V FE ++GYPRP + W+R T IK F Sbjct: 363 VQEREHAPRFDVKPEFLRKVEDVTALETEQVWFEIPIQGYPRPIVEWYRGTTRIKDGGRF 422 Query: 557 QMYYDDDN-VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + ++N + +LVI E ED+G + CVA N AG ++ L V Sbjct: 423 TISESEENDMYSLVIDEARTEDSGPYKCVASNDAGKTTALLNLDV 467 Score = 54.8 bits (126), Expect = 2e-05 Identities = 29/115 (25%), Positives = 61/115 (53%), Gaps = 5/115 (4%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 DE Y +Q +L + K+ + T ++++ P V +++ + V+FE +V G Sbjct: 81 DEGIYICDVQNELGKAFSKVEL----TVRKRNVKPQIVGEIKDAEEVERGEVRFEVRVTG 136 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +P+P++ W+R + F + +D + +L +R++ +D+GT+ VA+N G Sbjct: 137 FPKPRVEWYRGPVHLTDGGRFSISEKED-MYSLTVRDLKRDDSGTYKLVAQNTVG 190 Score = 54.4 bits (125), Expect = 3e-05 Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP +L P +G+ + C+V P+P +TW++ A++K ++ D + L Sbjct: 14 APSLSSQLMPVEVTEGNDIDLVCKVSVNPKPTVTWYKGDALVKLDDRISAHF-DGRFSRL 72 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I++ +D G + C +N G A S EL V Sbjct: 73 SIQKATKDDEGIYICDVQNELGKAFSKVELTV 104 >UniRef50_Q4S3Q6 Cluster: Chromosome 17 SCAF14747, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 17 SCAF14747, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1748 Score = 140 bits (339), Expect = 4e-31 Identities = 96/364 (26%), Positives = 167/364 (45%), Gaps = 23/364 (6%) Query: 478 NNYTQYLQKKLNEKIDKLPVFEKPTSEEQS-------MAPIFVEKLRPKHTPDGSTVQFE 530 +++ Q L ++ ++++ PV E + + PIF +KL+ +G V F Sbjct: 1388 SSFEQRLMSEIEFRLERTPVEESDEEVQHDDVPTGKCIVPIFDKKLKNFKAMEGVPVTFS 1447 Query: 531 CQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 C++ G P P++ WF+ I+K + ++ D D L I +D G +T +A N Sbjct: 1448 CKIVGIPVPKVYWFKDGKQILKKNVHYKKIRDGDGTCALHIESTTSDDDGNYTVMAANPQ 1507 Query: 590 GFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEG----IPPTFSKKPKAQY 644 G S + LIV+ P + A+ E P F + P Sbjct: 1508 GRISCSGHLIVQTGPPRPRCRHFILRGERRVQSCVREAEGEEAQERFFKPHFLQAPGDML 1567 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKF 703 EG L+C++ +P P++ WL G+ I PD + + E+ +H L I + + Sbjct: 1568 AHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHS----LVIDPLTQK 1623 Query: 704 QEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 GTYT +A N+ G++S + LK+ + K PPQ +E L++M + +G V L +VVG P Sbjct: 1624 DAGTYTCIASNKAGQSSFSLELKVVEKAMKYPPQFLEKLQNMGIPEGTPVRLECRVVGMP 1683 Query: 763 RPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P I W K+N + + + D + +++P + D G YT+ A+N GI + Sbjct: 1684 PPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSCTC 1743 Query: 819 VITV 822 + + Sbjct: 1744 RLDI 1747 Score = 79.0 bits (186), Expect = 1e-12 Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 10/110 (9%) Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DDDNVA 566 E L+ + G V EC+V G P P++ W+R + ++ S DF++ + + + Sbjct: 792 ENLQDVYASCGQLVALECRVRGVPSPRVVWYRDESQMEDSPDFRILQKKPRSPAESEEIC 851 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV---EAPLSDHGSEMTV 613 TLVI EVFPED+G FTC A N G SST L V +AP ++GS+ V Sbjct: 852 TLVIAEVFPEDSGMFTCTASNKFGTVSSTAALRVKVNDAPKHENGSQAVV 901 Score = 78.2 bits (184), Expect = 2e-12 Identities = 50/157 (31%), Positives = 80/157 (50%), Gaps = 9/157 (5%) Query: 461 HLTEEKGWVPAQYLMDENNYTQYLQKKLN-----EKIDKLPVFEKP-TSEEQSMAPIFVE 514 H TE++ P + + TQ LQ N ++ + E P +E + P F++ Sbjct: 579 HQTEDRP-EPGTGQLQDCGITQELQPNCNVQDAGKETEGCTPTETPYPTEPECEPPQFIQ 637 Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574 KLR + +GS VQ +C V G P P++ WF + ++ S D Q+ ++ + +L+I E F Sbjct: 638 KLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQI-LNNGELHSLIISEAF 696 Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610 ED G ++C A N G S++ E+ VE A SD E Sbjct: 697 EEDTGRYSCFASNVCGTDSTSAEIYVEGASSSDSEGE 733 Score = 77.8 bits (183), Expect = 3e-12 Identities = 55/195 (28%), Positives = 87/195 (44%), Gaps = 10/195 (5%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTKSDGDTHSI 789 P ++ M+ +G+ L +V G P P + W N KP+ + + +G HS+ Sbjct: 1557 PHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENG-VHSL 1615 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 ++ P KD G YT A N G + S + V E + PP F+ + Q + + E Sbjct: 1616 -VIDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKY--PPQFLEKLQNMGIPEGTP 1672 Query: 850 IKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 ++L RV P P I W ++N+ I + E IT D ++ + D+G Y A Sbjct: 1673 VRLECRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSA 1732 Query: 909 SNSAGKSSHGARVTI 923 N AG S R+ I Sbjct: 1733 KNEAGIVSCTCRLDI 1747 Score = 61.3 bits (142), Expect = 3e-07 Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 3/124 (2%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D YT K + L + K + P F+EKL+ P+G+ V+ EC+V G Sbjct: 1624 DAGTYTCIASNKAGQSSFSLEL--KVVEKAMKYPPQFLEKLQNMGIPEGTPVRLECRVVG 1681 Query: 536 YPRPQITWFRQT-AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 P P I W + +I + M D L+I+ +DAG +T AKN AG S Sbjct: 1682 MPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSC 1741 Query: 595 TTEL 598 T L Sbjct: 1742 TCRL 1745 Score = 57.6 bits (133), Expect = 4e-06 Identities = 66/262 (25%), Positives = 107/262 (40%), Gaps = 39/262 (14%) Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKS-- 782 + TG+ P + LK+ +G V S ++VG P P + W K+ K + K + K Sbjct: 1419 VPTGKCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYKKIR 1478 Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE------------------- 823 DGD ++ D+G YT+ A N +G S + V+ Sbjct: 1479 DGDGTCALHIESTTSDDDGNYTVMAANPQGRISCSGHLIVQTGPPRPRCRHFILRGERRV 1538 Query: 824 -----EPTEENAEPPLFINRF----QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 E E A+ F F ++ E +L +V+ P P + W N + I Sbjct: 1539 QSCVREAEGEEAQERFFKPHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIY 1598 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-----T 929 P + ++ + ++ D+G Y C+ASN AG+SS + + VEK Sbjct: 1599 PDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQSSFSLELKV-VEKAMKYPPQ 1657 Query: 930 FVKHLQKSYETEEGKTVILECQ 951 F++ LQ + EG V LEC+ Sbjct: 1658 FLEKLQ-NMGIPEGTPVRLECR 1678 Score = 56.0 bits (129), Expect = 1e-05 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 1/100 (1%) Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 PTE EPP FI + + + E ++L V P P + W+ + + S I + Sbjct: 625 PTEPECEPPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNN 684 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 GE L+I+ E D+G Y C ASN G S A + ++ Sbjct: 685 GELHSLIISEAFEE-DTGRYSCFASNVCGTDSTSAEIYVE 723 Score = 52.4 bits (120), Expect = 1e-04 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 4/104 (3%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTH 787 E EPPQ I+ L+S + +G V L V G P P + W K ++ P ++G+ H Sbjct: 629 ECEPPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELH 688 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 S+ I+ +D G Y+ A N G TSA I VE + ++E Sbjct: 689 SL-IISEAFEEDTGRYSCFASNVCGTDSTSAEIYVEGASSSDSE 731 Score = 51.2 bits (117), Expect = 3e-04 Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 12/174 (6%) Query: 1501 LTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXX-XXXXXXXXYKCIAFND 1555 L C G+P P++ W +GK L EN Y CIA N Sbjct: 1576 LDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNK 1635 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE----GIPPPEVIWYKNGN 1611 G+ S + + +K + + +++ +G +E G+PPP + W K+ + Sbjct: 1636 AGQSSFSLELKVVEK-AMKYPPQFLEKLQNMGIPEGTPVRLECRVVGMPPPVIFWKKDND 1694 Query: 1612 KLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 + N KE T++ T + I+ ++ + YT+ A N AG S L +Y Sbjct: 1695 SIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEAGIVSCTCRLDIY 1748 Score = 50.8 bits (116), Expect = 4e-04 Identities = 23/76 (30%), Positives = 37/76 (48%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + + ++ G+PPPEV W+ G +LEN + I + + I E + +Y+ Sbjct: 647 GSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELHSLIISEAFEEDTGRYSCF 706 Query: 1647 ASNTAGTSSVEVTLKV 1662 ASN GT S + V Sbjct: 707 ASNVCGTDSTSAEIYV 722 Score = 48.8 bits (111), Expect = 0.002 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 3/79 (3%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 PP+ I +L+++++ +G+K + + +G VRWF +G E++ S IQ+ +G+ L Sbjct: 632 PPQFIQKLRSREIAEGSKVQLDC-IVRGLPPPEVRWFCEGKELENSPDIQILNNGELHSL 690 Query: 1164 KIYDCDLDDAGEYSCEVGN 1182 I + +D G YSC N Sbjct: 691 IISEAFEEDTGRYSCFASN 709 Score = 47.6 bits (108), Expect = 0.004 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G+P PE++W NG + D + + +E + I L + + YT ASN AG S Sbjct: 1580 VSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQS 1639 Query: 1655 SVEVTLKVYDKPSK 1668 S + LKV +K K Sbjct: 1640 SFSLELKVVEKAMK 1653 Score = 46.4 bits (105), Expect = 0.009 Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 16/191 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D E + L+ +++ A +++W +G+ I P + + L Sbjct: 1557 PHFLQAPGDMLAHEGKLCRLDCKVSGLPAPELMWLVNGKPIYPDLYHKMLVRENGVHSLV 1616 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y+CI ++ S + E+ VVE PP+ + +LQN + +G E Sbjct: 1617 IDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKYPPQFLEKLQNMGIPEGTPVRLE 1676 Query: 1128 IELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQK-LKIYDCDLDDAGEYSC----EV 1180 + ++ W KD I I +T D L I DDAG Y+ E Sbjct: 1677 CRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVCLLIQPTRKDDAGWYTVSAKNEA 1736 Query: 1181 GNSKCTAILTV 1191 G CT L + Sbjct: 1737 GIVSCTCRLDI 1747 Score = 45.6 bits (103), Expect = 0.015 Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F +K +++ + EGS + L+C + +P P++ W +G+E+ +I + ++H Sbjct: 632 PPQFIQKLRSREIAEGSKVQLDCIVRGLPPPEVRWFCEGKELENSPDIQILNNGELHS-- 689 Query: 693 SVLKITNVKKFQEGTYTVVAVN 714 L I+ + G Y+ A N Sbjct: 690 --LIISEAFEEDTGRYSCFASN 709 Score = 44.0 bits (99), Expect = 0.046 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 10/86 (11%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTK--------EKTSVIRIKELKRSHSSKYTIEA 1647 + G+P P V+WY++ +++E+ ++ I K E+ + I E+ S +T A Sbjct: 811 VRGVPSPRVVWYRDESQMEDSPDFRILQKKPRSPAESEEICTLVIAEVFPEDSGMFTCTA 870 Query: 1648 SNTAGT--SSVEVTLKVYDKPSKPEG 1671 SN GT S+ + +KV D P G Sbjct: 871 SNKFGTVSSTAALRVKVNDAPKHENG 896 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 6/115 (5%) Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 + + +D T K + Q L + +R V E D E ++ V Sbjct: 1367 ITHHSSVDLTSCFPFFQEYKVSSFEQRLMSEIEFRLERTPVEESD-----EEVQHDDV-P 1420 Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530 K P +K LKN + +C G+P PKV W++DGK++ Y+ Sbjct: 1421 TGKCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYK 1475 Score = 41.1 bits (92), Expect = 0.33 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 1570 KPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEY-NITTKEK 1626 K ++ I ++ +K K G + I GIP P+V W+K+G + L+ + Y I + Sbjct: 1423 KCIVPIFDKKLKNFKAMEGVPVTFSCKIVGIPVPKVYWFKDGKQILKKNVHYKKIRDGDG 1482 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 T + I+ YT+ A+N G S L V P +P Sbjct: 1483 TCALHIESTTSDDDGNYTVMAANPQGRISCSGHLIVQTGPPRP 1525 Score = 40.3 bits (90), Expect = 0.57 Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 8/143 (5%) Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE----F 1286 K + D L+ + +L+I T+ D YTC+ + +S+ L+++VVE + Sbjct: 1595 KPIYPDLYHKMLVRENGVHSLVIDPLTQKDAGTYTCIASNKAGQSSFSLELKVVEKAMKY 1654 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH--TKPSIDSKSAS 1344 PP+ ++ + I G+ V L P P W ++ I K T + Sbjct: 1655 PPQFLEKLQNMGIPEGTPVRLECRVVGMPPPVIFWKKDNDSIPNTKERITMTQDATGYVC 1714 Query: 1345 LTIKKVENTDAGIYKLRLENNCG 1367 L I+ DAG Y + +N G Sbjct: 1715 LLIQPTRKDDAGWYTVSAKNEAG 1737 Score = 37.5 bits (83), Expect = 4.0 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 17/134 (12%) Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 T ++ +S+P +L + T P E L+ + G+ V L +V G P P + W Sbjct: 766 TATSLPLNAVSSVPPILTLPTQTSHP----ENLQDVYASCGQLVALECRVRGVPSPRVVW 821 Query: 769 CKNNKPVKALP--------TKSDGDTHSITILKPKKV--KDEGVYTLKAENSEGIAETSA 818 ++ ++ P +S ++ I L +V +D G++T A N G ++A Sbjct: 822 YRDESQMEDSPDFRILQKKPRSPAESEEICTLVIAEVFPEDSGMFTCTASNKFGTVSSTA 881 Query: 819 VITV---EEPTEEN 829 + V + P EN Sbjct: 882 ALRVKVNDAPKHEN 895 >UniRef50_UPI0000F2E010 Cluster: PREDICTED: similar to chondroitin polymerizing factor,; n=1; Monodelphis domestica|Rep: PREDICTED: similar to chondroitin polymerizing factor, - Monodelphis domestica Length = 1692 Score = 139 bits (337), Expect = 7e-31 Identities = 110/425 (25%), Positives = 185/425 (43%), Gaps = 12/425 (2%) Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +TW N I+P I + +G N L + DSG V + + G S AR+ + Sbjct: 856 LTWLLNGTAITPCNRIETSQNGPNHTLTLRCCQIS-DSGT---VTAQTEGSEST-ARLHV 910 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKEISGMDHREIIQEGR 980 ++ F++ LQ + TEEG+ + +E +TS W K + ++Q+GR Sbjct: 911 REAELLFLRRLQDA-RTEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDGR 969 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G+ C T L+V+ + L+D V E A ++E+ Sbjct: 970 VHRLIIHKVMVSDQGIYCCKSHHDRTQARLLVRPEQLKVRHPLEDVVVTEGGSATFQLEL 1029 Query: 1041 NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + W R G ++P +N +GH L + + D G S C A + Sbjct: 1030 SQSGVTGEWARGGVRLEPGRN-CQISAQGHNHCLVLSGLGLADTGTVSFTTDTLRCAARL 1088 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 V E+P I+ LQ+ +V +G+ ATFE EL++ A + W KDG E+ S +++ G + Sbjct: 1089 EVKEIPLAIVKGLQDLEVIEGDSATFECELSRTQADLTWDKDGQELSPSPRLRIQALGSR 1148 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAI-LTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 + L++ C DAG YSC VGNS+ +A LTV + ++ L + A Sbjct: 1149 RLLQLRCCGPKDAGTYSCCVGNSQASAARLTVRKKEVSVLQELKP-VKAREGDGATFKCT 1207 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + + +W V+ + + + +L + + +D E AKS+T L Sbjct: 1208 VSQPGIPGSWQLGGRVLRPGGRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQAKSSTHL 1267 Query: 1280 KVEVV 1284 +VEV+ Sbjct: 1268 EVEVL 1272 Score = 137 bits (332), Expect = 3e-30 Identities = 147/639 (23%), Positives = 253/639 (39%), Gaps = 37/639 (5%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 DI L R+ EP+ W+ +V D N+ + E M L I G YT Sbjct: 753 DIRLAGRVRQFLEPE--WI----SVVEDGNLELRSEGTRRM----LFIRAAHPSHAGNYT 802 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 A +L ++ E +++ L + +++G+ +V +TW Sbjct: 803 CQAGCEPAAPTL--TFPVQVSEIPQAKLVLELTPLTIQEGDDATFRCEVFPADAE-LTWL 859 Query: 770 KNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 N P + T +G H++T L+ ++ D G T + E SE A + V E Sbjct: 860 LNGTAITPCNRIETSQNGPNHTLT-LRCCQISDSGTVTAQTEGSESTAR----LHVRE-- 912 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI-TWYRNNEIISPSETITQNFDG 885 AE LF+ R Q+ +E + + +R I TW R + + + DG Sbjct: 913 ---AEL-LFLRRLQDARTEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDG 968 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 L+I V D G Y C + + + AR+ + E++ V+H + EG + Sbjct: 969 RVHRLIIHKVMVS-DQGIYCCKSHHDRTQ----ARLLVRPEQLK-VRHPLEDVVVTEGGS 1022 Query: 946 VILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 + + S + V+ +W + + +I +G D G + Sbjct: 1023 ATFQLELSQSGVTGEWARGGVRLEPGRNCQISAQGHNHCLVLSGLGLADTGTVSFTTDTL 1082 Query: 1005 ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064 + L VKE ++ LQD EV E D A E E++ AD+ W++DG+ + P + Sbjct: 1083 RCAARLEVKEIPLAIVKGLQDLEVIEGDSATFECELSRTQADLTWDKDGQELSPSP-RLR 1141 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCIL-RDESCTAEVTVVELPPEIITRLQNQKVNKGNK 1123 + G R L +R D G YSC + ++ A +TV + ++ L+ K +G+ Sbjct: 1142 IQALGSRRLLQLRCCGPKDAGTYSCCVGNSQASAARLTVRKKEVSVLQELKPVKAREGDG 1201 Query: 1124 ATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ATF+ +++ W G ++ +++ +G L + + +D+GE + G + Sbjct: 1202 ATFKCTVSQPGIPGSWQLGGRVLRPGGRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQA 1261 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 K + L VE + R P V A A L V + V W + K+ Sbjct: 1262 KSSTHLEVEVLPLQICRRPPREKTVLAGRRAALEVTVSRGGGHVRWLLGGVDLPPGPKYE 1321 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 S +LII D+ Y C + + T L VE Sbjct: 1322 FRSHGVTHSLIIHNVQPTDEGTYCCQAGEDSANTNLLVE 1360 Score = 114 bits (274), Expect = 3e-23 Identities = 128/590 (21%), Positives = 224/590 (37%), Gaps = 43/590 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + EG D C + + ++ WL G I P I + H L+ + Sbjct: 837 IQEGDDATFRCEVFPA-DAELTWLLNGTAITPCNRIETSQNGPNHTL--TLRCCQIS--D 891 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV--VGNP 762 GT T E A L + + + L+ +G+ + + + VG Sbjct: 892 SGTVTAQTEGSESTARLHV-------REAELLFLRRLQDARTEEGQELSMEVETSRVGG- 943 Query: 763 RPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 + +TW + KP+ P S DG H + I K V D+G+Y K+ + T A Sbjct: 944 QGIVTWLRGGKPLPEDPRFSVVQDGRVHRLIIHKVM-VSDQGIYCCKSHHDR----TQAR 998 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 + V P + PL +++ V E G+ ++++ V W R + P Sbjct: 999 LLVR-PEQLKVRHPL-----EDVVVTEGGSATFQLELSQSGVTG-EWARGGVRLEPGRNC 1051 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 + G N LV++ + D+G S + AR+ + + VK LQ E Sbjct: 1052 QISAQGHNHCLVLSGLGLA-DTG----TVSFTTDTLRCAARLEVKEIPLAIVKGLQ-DLE 1105 Query: 940 TEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 EG + EC+ S T W + +E+S I G D G Sbjct: 1106 VIEGDSATFECELSRTQADLTWDKDGQELSPSPRLRIQALGSRRLLQLRCCGPKDAGTYS 1165 Query: 999 CIV-KDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 C V Q ++ L V++ +++L+ + +E D A + ++ W+ G +++ Sbjct: 1166 CCVGNSQASAARLTVRKKEVSVLQELKPVKAREGDGATFKCTVSQPGIPGSWQLGGRVLR 1225 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 P + + G++ L + D GE + + V LP +I R +K Sbjct: 1226 PG-GRVRIRQEGNLHSLALSELQAEDSGEIQFQAGQAKSSTHLEVEVLPLQICRRPPREK 1284 Query: 1118 -VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V G +A E+ +++G VRW G ++ + G L I++ D G Y Sbjct: 1285 TVLAGRRAALEVTVSRGGGHVRWLLGGVDLPPGPKYEFRSHGVTHSLIIHNVQPTDEGTY 1344 Query: 1177 SCEVGNSKCTAILTVEE--PSIN-FTLRLPEFILVPANTDAYLTVEIPDE 1223 C+ G L VE+ PS + T ++ VP D L++ + + Sbjct: 1345 CCQAGEDSANTNLLVEKEGPSPSCLTFCSVCWLAVPQAPDPVLSISLASD 1394 Score = 109 bits (261), Expect = 1e-21 Identities = 132/551 (23%), Positives = 217/551 (39%), Gaps = 57/551 (10%) Query: 831 EPPLFINRFQE---ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGEN 887 EPP+ I Q+ + + + L +++ P + WY++ + SET+ G + Sbjct: 393 EPPVKILFPQDQVCVAAESSERVVLSCELSQAGAP-VHWYKDGMVAKESETLLLERKGLH 451 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTV 946 L++ + D G + C AG VTI V V+ + + T + V Sbjct: 452 CHLILPAAQPQ-DGGKFVC----KAGDDQAVFHVTITEPPVQIVQPQDEMFLTAVTSERV 506 Query: 947 ILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 +L CQ S + WY N E+ + + EG D G C +D Sbjct: 507 VLMCQVSQPRALVGWYKNGMEVEESKYLVLESEGLQHRLVLPSVRLQDGGEFVCSTRDDS 566 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVK--EKDVAILEVEINSETADVVWERDGEIIKPKKNKY 1063 L V E + + + V + +L E++ A V W +DG ++ + Sbjct: 567 AFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAGAPVRWYKDGLEVE-ENEAL 625 Query: 1064 DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR-----LQNQKV 1118 E G +L + D GE+ C D+S V+V +PPE I R LQ Q Sbjct: 626 VLESEGPYHRLVLPAAQPQDGGEFVCDAGDDSAFFIVSVT-VPPERIVRPAARFLQLQFR 684 Query: 1119 NKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 + G + E+ A V W+KDG E++ S ++L +G + L + DAGEY C Sbjct: 685 SPG-RVELRCEVAPVGARVCWYKDGLEVEASEDLKLGAEGPIRTLTLPQARPQDAGEYVC 743 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 E + +++F +RL + + L+ W SV+ED Sbjct: 744 E-----------TRDEAVSFDIRLAGRV---------------RQFLEPEWI---SVVED 774 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCV--LLDAKSTTKLKVEVVEFP-PKIVDYER 1295 L S+ +R L IR YTC A T V+V E P K+V Sbjct: 775 -GNLELRSEGTRRMLFIRAAHPSHAGNYTCQAGCEPAAPTLTFPVQVSEIPQAKLVLELT 833 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPND-EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 I+ G D T + FP + W++N I C + S + + +LT++ + +D Sbjct: 834 PLTIQEGDDATFRC--EVFPADAELTWLLNGTAITPCNRIETSQNGPNHTLTLRCCQISD 891 Query: 1355 AGIYKLRLENN 1365 +G + E + Sbjct: 892 SGTVTAQTEGS 902 Score = 108 bits (260), Expect = 1e-21 Identities = 98/440 (22%), Positives = 176/440 (40%), Gaps = 17/440 (3%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 I K + L+ ++R P + WY++ I S+ + +G LVI + Sbjct: 316 IEAKSLEQVVLLCELSRAGAP-VHWYKDGLEIEESQAMVLENEGLQCRLVIPAAQPQ-HG 373 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFV-KHLQKSYETEEGKTVILECQTSHT-VSTK 959 G++ C AG+ S VTI V + Q E + V+L C+ S Sbjct: 374 GEFVC----KAGEDSAFFMVTIKEPPVKILFPQDQVCVAAESSERVVLSCELSQAGAPVH 429 Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019 WY + + + ++G D G C D + + + E + Sbjct: 430 WYKDGMVAKESETLLLERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFHVTITEPPVQI 489 Query: 1020 IRKLQDFEVKE--KDVAILEVEINSETADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYI 1076 ++ + + + +L +++ A V W ++G ++ +++KY E G +L + Sbjct: 490 VQPQDEMFLTAVTSERVVLMCQVSQPRALVGWYKNG--MEVEESKYLVLESEGLQHRLVL 547 Query: 1077 RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN--KGNKATFEIELTKGD 1134 + + D GE+ C RD+S +TV E P +I+ V + EL++ Sbjct: 548 PSVRLQDGGEFVCSTRDDSAFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAG 607 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 A VRW+KDG E++ + + L +G +L + D GE+ C+ G+ I++V P Sbjct: 608 APVRWYKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVCDAGDDSAFFIVSVTVP 667 Query: 1195 SINFTLRLPEFILVPANTDAY--LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 F+ + + L E+ V WYK +E +E L ++ RT Sbjct: 668 PERIVRPAARFLQLQFRSPGRVELRCEVAPVGARVCWYKDGLEVEASEDLKLGAEGPIRT 727 Query: 1253 LIIRKCTEDDQCEYTCVLLD 1272 L + + D EY C D Sbjct: 728 LTLPQARPQDAGEYVCETRD 747 Score = 103 bits (246), Expect = 7e-20 Identities = 83/360 (23%), Positives = 142/360 (39%), Gaps = 12/360 (3%) Query: 937 SYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 S E + + V+L C+ S WY + EI + EG G Sbjct: 315 SIEAKSLEQVVLLCELSRAGAPVHWYKDGLEIEESQAMVLENEGLQCRLVIPAAQPQHGG 374 Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQD---FEVKEKDVAILEVEINSETADVVWERD 1052 C + M+ +KE P I QD + + +L E++ A V W +D Sbjct: 375 EFVCKAGEDSAFFMVTIKEP-PVKILFPQDQVCVAAESSERVVLSCELSQAGAPVHWYKD 433 Query: 1053 GEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR 1112 G + K + E++G L + D G++ C D+ VT+ E P +I+ Sbjct: 434 GMVAKESETLL-LERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFHVTITEPPVQIVQP 492 Query: 1113 LQNQKVNK--GNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDL 1170 + + ++++ ALV W+K+G E++ S ++ L +G + +L + L Sbjct: 493 QDEMFLTAVTSERVVLMCQVSQPRALVGWYKNGMEVEESKYLVLESEGLQHRLVLPSVRL 552 Query: 1171 DDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD-AYLTVEIPDETLDVTW 1229 D GE+ C + LTV EP + E + +++ LT E+ V W Sbjct: 553 QDGGEFVCSTRDDSAFFTLTVTEPPVKILFPRDEVSVAAVSSERVVLTCELSRAGAPVRW 612 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 YK +E+ E L S+ L++ D E+ C DA + + V PP+ Sbjct: 613 YKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVC---DAGDDSAFFIVSVTVPPE 669 Score = 81.0 bits (191), Expect = 3e-13 Identities = 153/721 (21%), Positives = 274/721 (38%), Gaps = 71/721 (9%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C L P + W G EI +E+ ++ +E++ + C ++ I + G + Sbjct: 324 VVLLCELSRAGAP-VHWYKDGLEI--EESQAMVLENE-GLQCRLV-IPAAQPQHGGEF-- 376 Query: 711 VAVNREGEASLPIVLKIKTGEKEPP-QVIEPLKSMIV--RQGESVILSAQVVGNPRPTIT 767 V + GE S ++ IK EPP +++ P + V E V+LS ++ P + Sbjct: 377 --VCKAGEDSAFFMVTIK----EPPVKILFPQDQVCVAAESSERVVLSCELSQAGAP-VH 429 Query: 768 WCKNNKPVKALPTK--SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 W K+ K T H IL + +D G + KA + + + +T+ EP Sbjct: 430 WYKDGMVAKESETLLLERKGLHCHLILPAAQPQDGGKFVCKAGDDQAVFH----VTITEP 485 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 + +P F E+ + L+ +V++ P + WY+N + S+ + +G Sbjct: 486 PVQIVQPQ--DEMFLTAVTSER--VVLMCQVSQ-PRALVGWYKNGMEVEESKYLVLESEG 540 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 LV+ +V + D G++ C S + VT K+ F + + S + Sbjct: 541 LQHRLVLPSVRLQ-DGGEFVC--STRDDSAFFTLTVTEPPVKILFPRD-EVSVAAVSSER 596 Query: 946 VILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 V+L C+ S +WY + E+ + + EG D G C D Sbjct: 597 VVLTCELSRAGAPVRWYKDGLEVEENEALVLESEGPYHRLVLPAAQPQDGGEFVCDAGDD 656 Query: 1005 ETSTMLVVKETIP--EFIRKLQDF---EVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 S +V T+P +R F + + L E+ A V W +DG ++ Sbjct: 657 --SAFFIVSVTVPPERIVRPAARFLQLQFRSPGRVELRCEVAPVGARVCWYKDGLEVEAS 714 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 ++ G IR L + D GEY C RDE+ + + + L + L+ + ++ Sbjct: 715 ED-LKLGAEGPIRTLTLPQARPQDAGEYVCETRDEAVSFD---IRLAGRVRQFLEPEWIS 770 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 E+ ++G + + + N Y C AG CE Sbjct: 771 VVEDGNLELR-SEGTRRMLFIRAAHPSHAGN---------------YTC---QAG---CE 808 Query: 1180 VGNSKCTAILTVEE-PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 T + V E P L L + + DA E+ ++TW + I Sbjct: 809 PAAPTLTFPVQVSEIPQAKLVLELTP-LTIQEGDDATFRCEVFPADAELTWLLNGTAITP 867 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298 + + TL +R C D T ++ST +L V E + ++ R Sbjct: 868 CNRIETSQNGPNHTLTLRCCQISDSGTVTAQTEGSESTARLHVREAEL--LFLRRLQDAR 925 Query: 1299 IKRGSDVTLLVD-YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 + G ++++ V+ + Q W+ K + + D + L I KV +D GI Sbjct: 926 TEEGQELSMEVETSRVGGQGIVTWLRGGKPLPEDPRFSVVQDGRVHRLIIHKVMVSDQGI 985 Query: 1358 Y 1358 Y Sbjct: 986 Y 986 Score = 36.7 bits (81), Expect = 7.0 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 1/94 (1%) Query: 1100 VTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDG 1158 V V + I RL + V +G A +E+ L RW +DG E+ S I T Sbjct: 8 VAAVAVKGPITRRLPRKLDVLEGENAVLSVEVRGAKVLGRWTRDGQELPASPRIIQTSSN 67 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 L + DAG + +G+S ++ L V+ Sbjct: 68 HTHTLVLVGVTRQDAGVVTFSLGSSHTSSRLRVK 101 >UniRef50_P52179 Cluster: Myomesin-1; n=19; Euteleostomi|Rep: Myomesin-1 - Homo sapiens (Human) Length = 1451 Score = 139 bits (337), Expect = 7e-31 Identities = 105/402 (26%), Positives = 170/402 (42%), Gaps = 18/402 (4%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727 P + + E +R V + WKPP G E Y +EK E W +V ++ + Sbjct: 503 PPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFA 561 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALES-EPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L E Y FRV N G E E+ E V+ LD+P D SV + Sbjct: 562 LFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT-SVVV 620 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI--QKLSINTTYQFRIYARN 1843 +W E ++ Y +E G KW+ R L +Y FR+ A N Sbjct: 621 SW--EESKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVN 678 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 G S + I + + PPS P + ES S+ L W +P+ GG+ IT Y + Sbjct: 679 AAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVN 738 Query: 1904 FKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVR 1958 ++ V GK W + + I N+KE F+++A N G+ P+ S+ + Sbjct: 739 YREVIDGVPGK-WREANVKAVREEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK 797 Query: 1959 LEKHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK-TMWMEV 2016 E+ VP PP + L+ V + ++ W P G P+ GY + +++ K W + Sbjct: 798 CEEWTIAVPGPPHS-LKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGL 856 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + + +R L E +Y+ R+ A N+ G+ +P + P Sbjct: 857 NEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGP 898 Score = 124 bits (299), Expect = 3e-26 Identities = 114/498 (22%), Positives = 184/498 (36%), Gaps = 42/498 (8%) Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 PE+ WY+NG L K + + + L + YTI + Sbjct: 303 PEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 362 Query: 1662 VYDKPSKPEG----PVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V D ++ EG P+ ++ E +++ + I WK P DGG + Y I+K E + W + Sbjct: 363 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 422 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF------SEALESEPIVIKTALDVPSX 1769 D + + L E Y+FRV A N +G SEA+ + K L P Sbjct: 423 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLS 482 Query: 1770 XXXXXXXXXIDNES--------------------VYITWFPSEKNGGSPIIDYKVEIKQE 1809 + S V ++W P + G I+ + + + Sbjct: 483 TLDWTVIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAG 542 Query: 1810 GKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 + W+ + + L+ +Y FR+ N G P + + +G L P Sbjct: 543 TENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP 602 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 P + S +T SV + W E S + Y IE W H Sbjct: 603 KAPGKIIPSRNTDTSVVVSWEE--SKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFT 660 Query: 1927 IENIKEKDEIIFRISAENTVGVS-LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 + IFR+ A N G+S +S+++ ++ PSPP + ++V+ Sbjct: 661 CHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVL- 719 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTM---WMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 W P+ GGA + GY + R+V + W E V + I +L EN Y ++ Sbjct: 720 GWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVA 779 Query: 2043 ARNEIGLSEPLESDEPFK 2060 A N GL P E FK Sbjct: 780 AMNMAGLGAPSAVSECFK 797 Score = 68.9 bits (161), Expect = 1e-09 Identities = 58/238 (24%), Positives = 94/238 (39%), Gaps = 13/238 (5%) Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSKPEGPVIMREISR 1680 KT L S + + A N AG S S + +K P P + E R Sbjct: 655 KTHRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFR 714 Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDN---NRWIKVADVDRDVETYCIQKLNENCEY 1737 +S+ + WK P GG E+T Y + E + +W + E Y I L EN Y Sbjct: 715 DSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVY 774 Query: 1738 MFRVIAQNPVGF-SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 F+V A N G + + SE + + +S+ + W P +G Sbjct: 775 QFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGR 834 Query: 1797 SPIIDYKVEIKQEGK--KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLP 1850 +P+ Y V++K++ K +W+ +++ L +Y FR+ A N+ G P Sbjct: 835 TPVTGYFVDLKEKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKP 892 Score = 67.7 bits (158), Expect = 3e-09 Identities = 73/313 (23%), Positives = 121/313 (38%), Gaps = 35/313 (11%) Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQ 1836 + + + I+W +GGSPI+ Y ++ + G W AR + L +Y Sbjct: 386 NKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYI 445 Query: 1837 FRIYARNEIGTSLPYTSDDKI--------------------TIGKTLTPPSQ------PR 1870 FR+ A N++G P + + T+ T PS+ P Sbjct: 446 FRVRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWTVIVTEEEPSEGIVPGPPT 505 Query: 1871 NFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHEHCIEN 1929 + V+E+T V L W P G I Y +E ++W ++ T + + + Sbjct: 506 DLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFD 564 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIVMTSWG 1988 + E FR+ N+ GV P+E+ V + +P P + R +++V+ SW Sbjct: 565 LAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVV-SW- 622 Query: 1989 TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 E L+GY I W V T +F L +Y+ R+ A N G Sbjct: 623 -EESKDAKELVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAG 681 Query: 2049 LSEPLESDEPFKV 2061 LSE + E +V Sbjct: 682 LSEYSQDSEAIEV 694 Score = 57.2 bits (132), Expect = 5e-06 Identities = 58/243 (23%), Positives = 99/243 (40%), Gaps = 25/243 (10%) Query: 1284 VEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + F K V + RE + G V + + + F QP W N + K + + Sbjct: 269 IHFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEIRWYRNGVPLSPSKWVQTLWSGE 327 Query: 1342 SASLTIKKVENTDAGIYKLRL------ENNCGHADV-EMNVTILDKPSPPGKPNILEIDS 1394 A+LT + D G+Y +R+ E + V + + I P+ P LE + Sbjct: 328 RATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANK 387 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452 I I W +P G S I+ Y ++ E+ T W + + + + L SY FR Sbjct: 388 DYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFR 447 Query: 1453 AYAVNEVDISDASETTEYYKVI---KETKIQSP----------TVEKPLKNITTEPNEDI 1499 AVN++ I S +E + ++ +++SP T E+P + I P D+ Sbjct: 448 VRAVNKMGIGFPSRVSEAVAALDPAEKARLKSPLSTLDWTVIVTEEEPSEGIVPGPPTDL 507 Query: 1500 ELT 1502 +T Sbjct: 508 SVT 510 Score = 53.2 bits (122), Expect = 8e-05 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTT--EW--ISVKNITK 1435 PSPP LE S+ + W +P+ TG + I Y V Y+E ID +W +VK + + Sbjct: 701 PSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKAVRE 760 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 I NLK N Y+F+ A+N + S +E +K +E I P LK Sbjct: 761 EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFK-CEEWTIAVPGPPHSLK 813 Score = 51.2 bits (117), Expect = 3e-04 Identities = 47/233 (20%), Positives = 86/233 (36%), Gaps = 14/233 (6%) Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 L + +++ + +E+ + AP F+ K R + V+ C + G+P P++TW++ Sbjct: 118 LRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKN 177 Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 I + Y + + TL I ED + A N G S+ ++V+ Sbjct: 178 QVPINVHANPGKYIIESRYGMHTLEINACDFEDTAQYRASAMNVKGELSAYASVVVKRYK 237 Query: 605 SDHGSEMTVXXXXXXXXXXXXA--DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE 662 + F K + EG + L CR+V PE Sbjct: 238 GEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPE 297 Query: 663 -----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 P+I W G + P + + + + L +++ K EG YT+ Sbjct: 298 IKHFQPEIRWYRNGVPLSPSKWVQTLWSGER----ATLTFSHLNKEDEGLYTI 346 Score = 48.8 bits (111), Expect = 0.002 Identities = 81/384 (21%), Positives = 149/384 (38%), Gaps = 30/384 (7%) Query: 457 YVQKHLTEEKGWVPAQYLMD---ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFV 513 +++K E++G Q L D N+ T L + +K+ K F++ + P FV Sbjct: 1070 FMEKLQDEDEGTYTFQ-LQDGKATNHSTVVLVGDVFKKLQKEAEFQRQ-EWIRKQGPHFV 1127 Query: 514 EKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATLVIRE 572 E L + T + V +C+V + I W++ I + D + TL+I E Sbjct: 1128 EYLSWEVTGE-CNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDGICTLLITE 1183 Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEA---PLSDHGSEMTVXXXXXXXXXXXXADIL 629 +DAG + + K+ G S +L+ EA + + ++ + L Sbjct: 1184 FSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQL 1243 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 + + K + GS I R+ + WL E P N D Sbjct: 1244 YSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINE---PTPN-------DKG 1293 Query: 690 MYCSVLKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VR 747 Y V+++ + K + T + E A + + EK +V+ L ++ ++ Sbjct: 1294 KY--VMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQ 1351 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYT 804 +G+++ L+ V G+P P ++W KN K + K + + + D G Y Sbjct: 1352 EGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYG 1411 Query: 805 LKAENSEGIAETSAVITVEEPTEE 828 L +N G + ++V P EE Sbjct: 1412 LVVKNKYGSETSDFTVSVFIPEEE 1435 Score = 44.8 bits (101), Expect = 0.026 Identities = 55/207 (26%), Positives = 85/207 (41%), Gaps = 39/207 (18%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTK----SDGDTH 787 P +I+P +S V + E+V L + G P P +TW KN P+ A P K S H Sbjct: 141 PEFIIKP-RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 199 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-----------------PTEENA 830 ++ I +D Y A N +G A + V+ P Sbjct: 200 TLEI-NACDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGV 258 Query: 831 EPPLFINRFQ-------EITVKEKG-TIKLVARVTRNPV-----PSITWYRNNEIISPSE 877 P + +RF+ +++ +G T+ L RV P P I WYRN +SPS+ Sbjct: 259 TPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSK 318 Query: 878 TITQNFDGENIELVITNVDSEIDSGDY 904 + + GE L ++++ E D G Y Sbjct: 319 WVQTLWSGERATLTFSHLNKE-DEGLY 344 Score = 44.0 bits (99), Expect = 0.046 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 5/117 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP ++ E S + + W P G+ I+Y+ VE E T W V + + Sbjct: 501 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEKCEAGTENWQRVNTELPVKSPR 559 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITT 1493 ++ +L SY FR N + + SE TE V + I ++P P +N T Sbjct: 560 FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDT 616 Score = 43.2 bits (97), Expect = 0.081 Identities = 54/213 (25%), Positives = 98/213 (46%), Gaps = 20/213 (9%) Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDG 1053 V K + K+ E +++ P F+ L +EV + +L+ ++ + + +VW +D Sbjct: 1103 VFKKLQKEAEFQRQEWIRKQGPHFVEYLS-WEVTGECNVLLKCKVANIKKETHIVWYKDE 1161 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAEVTVV-----ELP 1106 I + K+DF K G I L I S D G Y IL+D+ + + +V EL Sbjct: 1162 REISVDE-KHDF-KDG-ICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELM 1218 Query: 1107 PEII-------TRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 E+ T L+ Q +G + + D V W +GS I++S+ ++ + G+ Sbjct: 1219 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1278 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 + L+I + +D G+Y E+ + K TV+ Sbjct: 1279 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVD 1311 Score = 42.3 bits (95), Expect = 0.14 Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 9/141 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKN--ITKTQ 1437 P PP E+ S+ + W P ++G + + Y V+ +E +W + I Sbjct: 806 PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGLNEAAIKNVY 865 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 ++ LK SY FR A+N+ + S+ V+ ET+ P ++ + N+ + Sbjct: 866 LKVRGLKEGVSYVFRVRAINQAGVGKPSDLAG--PVVAETR---PGRKEVVVNVDDDGVI 920 Query: 1498 DIELTCIFGGVPQPKVTWYRD 1518 + C P+ + +W +D Sbjct: 921 SLNFEC-DKMTPKSEFSWSKD 940 Score = 41.5 bits (93), Expect = 0.25 Identities = 19/82 (23%), Positives = 36/82 (43%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +T++E + L V +P P ++W +N + ++ ++ F+ N S DS Sbjct: 1348 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADS 1407 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G Y V N G + V++ Sbjct: 1408 GKYGLVVKNKYGSETSDFTVSV 1429 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 10/124 (8%) Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++R N+ G + VT+ LD P PGK +S+ + W+E ++ Sbjct: 573 FRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDA--KE 630 Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ Y +E + +W N + + + L T SY FR AVN +S+ S+ +E Sbjct: 631 LVGYYIEANVAGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSE 690 Query: 1470 YYKV 1473 +V Sbjct: 691 AIEV 694 Score = 40.3 bits (90), Expect = 0.57 Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETITQNFDGENI 888 P FI + + TV EK +KL + P P +TWY+N N +P + I ++ G + Sbjct: 141 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH- 199 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 L I D E D+ Y+ A N G+ S A V + K F Sbjct: 200 TLEINACDFE-DTAQYRASAMNVKGELSAYASVVVKRYKGEF 240 Score = 40.3 bits (90), Expect = 0.57 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650 +T + G PPPEV W KN L N+ + +T+ I + + S KY + N Sbjct: 1358 LTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNK 1417 Query: 1651 AGTSSVEVTLKVY 1663 G+ + + T+ V+ Sbjct: 1418 YGSETSDFTVSVF 1430 Score = 39.5 bits (88), Expect = 0.99 Identities = 20/89 (22%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G + C V G P P+++W + + + + ++ A I V D+G + Sbjct: 1352 EGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGKYG 1411 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEM 611 V KN G S T++ V + + + M Sbjct: 1412 LVVKNKYG--SETSDFTVSVFIPEEEARM 1438 Score = 39.1 bits (87), Expect = 1.3 Identities = 64/280 (22%), Positives = 115/280 (41%), Gaps = 40/280 (14%) Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184 FE + + W KD + S +++ G K K+ D +DD G YSC+V ++ Sbjct: 924 FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDG 983 Query: 1185 CTAILTVEEPSINFTLRLP---EFILVPANTDAYLTVEIPDETLDVTW------------ 1229 + ++E + L L +F VP ++ L VEI ++ W Sbjct: 984 IASSYLIDEEELKRLLALSHEHKFPTVPVKSE--LAVEILEKGQVRFWMQAEKLSGNAKV 1041 Query: 1230 ---YKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK----STTKLKV 1281 + +K + E + K + + + + K ++D+ YT L D K ST L Sbjct: 1042 NYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVG 1101 Query: 1282 EVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH------- 1333 +V + K +++R E+ K+G + ++ + N IKK H Sbjct: 1102 DVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDE 1161 Query: 1334 TKPSIDSKS------ASLTIKKVENTDAGIYKLRLENNCG 1367 + S+D K +L I + DAGIY++ L+++ G Sbjct: 1162 REISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRG 1201 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 9/90 (10%) Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798 R+GE++ L +VV P +P I W +N P+ K + T G+ ++T K + Sbjct: 281 REGETMSLGCRVVITPEIKHFQPEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNK-E 339 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEE 828 DEG+YT++ E + SA + V + E Sbjct: 340 DEGLYTIRVRMGEYYEQYSAYVFVRDADAE 369 Score = 37.5 bits (83), Expect = 4.0 Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGI 1357 I+ G + L + P P W+ N K + + H ++ ++A TI V D+G Sbjct: 1350 IQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTADSGK 1409 Query: 1358 YKLRLENNCGHADVEMNVTI 1377 Y L ++N G + V++ Sbjct: 1410 YGLVVKNKYGSETSDFTVSV 1429 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 4/104 (3%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P + EG + L C + P P+++WL + + ++ ++ E+ Y I Sbjct: 1345 PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAY---FTING 1401 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ-VIEPLK 742 V G Y +V N+ G + + + E+E +E LK Sbjct: 1402 VSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLK 1445 >UniRef50_Q14896 Cluster: Myosin-binding protein C, cardiac-type; n=41; Euteleostomi|Rep: Myosin-binding protein C, cardiac-type - Homo sapiens (Human) Length = 1273 Score = 139 bits (336), Expect = 9e-31 Identities = 114/462 (24%), Positives = 200/462 (43%), Gaps = 28/462 (6%) Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASL-TIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 +DEW+ + K++ + + +K S+ T++ E D G+Y + ++N G V + V Sbjct: 707 SDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVK 766 Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--IT 1434 ++D P P P I + S + W+ P G I+ Y++E ++ + W+ + I Sbjct: 767 VIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQ 826 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI----KETKIQSPTVEKPLKN 1490 + + + Y R YAVN + +S S ++ + I + T + V + Sbjct: 827 ELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVS 886 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDG-KKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 + P E + GG+ V + +G + A ++ Sbjct: 887 LKWRPPERVGA----GGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFR 942 Query: 1550 CIAFNDHGE---VETSCVVGIQ---QKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPP 1601 A N G V T+ V +Q Q+P + + ++Q + KVG+ + +G P Sbjct: 943 VRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRH-LRQTIQKKVGEPVNLLIPFQGKPR 1001 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P+V W K G L + E +I +++ I+ +R HS Y + + L+ Sbjct: 1002 PQVTWTKEGQPLAGE-EVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQ 1060 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 V DKPS P+ + + + +V +EWKPP D G EL Y ++K + W V + R Sbjct: 1061 VVDKPSPPQ-DLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYR 1119 Query: 1722 DVETYC-IQKLNENCEYMFRVIAQNPVGFSE--ALESEPIVI 1760 T+C + +L Y FRV +QN VGFS+ A EP+ I Sbjct: 1120 --RTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFI 1159 Score = 112 bits (269), Expect = 1e-22 Identities = 109/468 (23%), Positives = 195/468 (41%), Gaps = 38/468 (8%) Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 E + + T + S+ ++ ++ YT+ N G V +T+KV D P P P Sbjct: 719 ETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK 778 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLN 1732 I + +S T++W+PP DGG + Y +E+ + + RW+++ D+ +++ ++ +++ Sbjct: 779 ISN-VGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQEL-SHEARRMI 836 Query: 1733 ENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 E Y RV A N +G S + S+P + + PS + + +V + W P Sbjct: 837 EGVVYEMRVYAVNAIGMSRPSPASQPFM---PIGPPS-EPTHLAVEDVSDTTVSLKWRPP 892 Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTS 1848 E+ G + Y VE EG +W I + L FR+ A N G Sbjct: 893 ERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPG 952 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KT 1906 P T+ + +T+ + L P + ++ + V G P+ N +I F K Sbjct: 953 APVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKV-----------GEPV-NLLIPFQGKP 1000 Query: 1907 VKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISA----ENTVGVSLPTESQSVRLEK 1961 +WTK + G E I N D I+F +A T V++ E+ + Sbjct: 1001 RPQVTWTKEGQPLAG--EEVSIRN-SPTDTILFIRAARRVHSGTYQVTVRIENMEDKATL 1057 Query: 1962 HATVPSPPTAPLEIRMV---GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK 2018 V P+ P ++R+ G N+ + W P+ G L GY + D W V + Sbjct: 1058 VLQVVDKPSPPQDLRVTDAWGLNVAL-EWKPPQDVGNTELWGYTVQKADKKTMEWFTVLE 1116 Query: 2019 VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 + +L + Y R++++N +G S+ + + IP G Sbjct: 1117 -HYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPG 1163 Score = 111 bits (267), Expect = 2e-22 Identities = 80/257 (31%), Positives = 129/257 (50%), Gaps = 11/257 (4%) Query: 1019 FIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 F +KL+ ++V + L VE+ A+V W ++G+ I+ +Y FE G R L I Sbjct: 365 FQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQ-MSGRYIFESIGAKRTLTIS 423 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTVVELPPEIITR-LQNQKVNKGNKATFEIELTKGDAL 1136 S+ D+ Y C++ E C+ E+ V E PP +ITR L++Q V G + FE E+++ A Sbjct: 424 QCSLADDAAYQCVVGGEKCSTELFVKE-PPVLITRPLEDQLVMVGQRVEFECEVSEEGAQ 482 Query: 1137 VRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 V+W KDG E+ + DG++ L I + L+DAG Y+ + A L V+E Sbjct: 483 VKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEK 542 Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTE-KFTLISDVKKRT 1252 + + + ++V A A E+ DE + W K K ++ D+ K + I V K Sbjct: 543 KLEVYQSIAD-LMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHK-- 599 Query: 1253 LIIRKCTEDDQCEYTCV 1269 L I T D+ +Y+ V Sbjct: 600 LTIDDVTPADEADYSFV 616 Score = 101 bits (241), Expect = 3e-19 Identities = 80/284 (28%), Positives = 124/284 (43%), Gaps = 7/284 (2%) Query: 924 DVEKVT-FVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE-GR 980 D +K T F K L+ +Y+ +G + L + + H KW N +EI M R I + G Sbjct: 358 DEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQ-MSGRYIFESIGA 416 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D +C+V ++ ST L VKE R L+D V E E+ Sbjct: 417 KRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEV 476 Query: 1041 NSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + E A V W +DG E+ + + KY F+K G L I + D G Y+ AE Sbjct: 477 SEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAE 536 Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 + V E E+ + + V ++A F+ E++ + W K+G E+ + I+++ G+ Sbjct: 537 LIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGR 596 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKC--TAILTVEEPSINFTLR 1201 KL I D D +YS C +A L E I+F R Sbjct: 597 VHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPR 640 Score = 84.2 bits (199), Expect = 4e-14 Identities = 54/168 (32%), Positives = 77/168 (45%), Gaps = 3/168 (1%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 +V+KG+K +EL DA V+W K+G EIQ S G K+ L I C L D Y Sbjct: 374 QVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGRYIFESIGAKRTLTISQCSLADDAAY 433 Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK--KS 1234 C VG KC+ L V+EP + T L E LV E+ +E V W K + Sbjct: 434 QCVVGGEKCSTELFVKEPPVLITRPL-EDQLVMVGQRVEFECEVSEEGAQVKWLKDGVEL 492 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 E+T K+ D ++ LII + +D Y ++ +L V+ Sbjct: 493 TREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQ 540 Score = 83.4 bits (197), Expect = 6e-14 Identities = 60/239 (25%), Positives = 106/239 (44%), Gaps = 19/239 (7%) Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 K G V LL+ +Q P+P W + + + L I+ +G Y+ Sbjct: 985 KVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG-EEVSIRNSPTDTILFIRAARRVHSGTYQ 1043 Query: 1360 L--RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + R+EN A + + V +DKPSPP + + ++ + W P++ GN+ + Y V Sbjct: 1044 VTVRIENMEDKATLVLQV--VDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTV 1101 Query: 1418 EYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + + T EW +V ++ +T + L + Y FR ++ N V SD + TT+ I Sbjct: 1102 QKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPR 1161 Query: 1477 TKI-------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 I ++P+ +PL N + L C G P+PK++W+++G L Sbjct: 1162 PGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDL 1220 Score = 79.8 bits (188), Expect = 8e-13 Identities = 49/155 (31%), Positives = 73/155 (47%), Gaps = 8/155 (5%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 +E +++DE ++ ++ +N VG E Q K VP P AP +I VG + Sbjct: 737 VEGAEKEDEGVYTVTVKNPVG-----EDQVNLTVKVIDVPDAPAAP-KISNVGEDSCTVQ 790 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P +DGG P+LGY + + WM + + L R + E Y +R+YA N Sbjct: 791 WEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNA 850 Query: 2047 IGLSEPLESDEPFKVI--PGEGSHADEEPGEQTEV 2079 IG+S P + +PF I P E +H E T V Sbjct: 851 IGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTV 885 Score = 56.4 bits (130), Expect = 8e-06 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 1/97 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S AP F + L + G T C V G P+P+I+WF+ + F+M + V Sbjct: 1177 SEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRM-FSKQGVL 1235 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 TL IR+ P D G + C A N G A L V P Sbjct: 1236 TLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVP 1272 Score = 47.2 bits (107), Expect = 0.005 Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 3/100 (3%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 E+ S F +L V LTVE+ D +V W K I+ + ++ S KR Sbjct: 359 EKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGRYIFESIGAKR 418 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 TL I +C+ D Y CV+ K +T+L V+ PP ++ Sbjct: 419 TLTISQCSLADDAAYQCVVGGEKCSTEL---FVKEPPVLI 455 Score = 46.4 bits (105), Expect = 0.009 Identities = 26/77 (33%), Positives = 37/77 (48%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 +V G+ A FE E + VRW + GS+I SN L +G + L + + D G Y Sbjct: 20 EVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSY 79 Query: 1177 SCEVGNSKCTAILTVEE 1193 + G+SK L V E Sbjct: 80 AVIAGSSKVKFDLKVIE 96 Score = 41.9 bits (94), Expect = 0.19 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 K+ + F +K + EV A+ E E V W+R G I NKY G Sbjct: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISAS-NKYGLATEGTRH 64 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 L +R D+G Y+ I ++ V+E Sbjct: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIE 96 Score = 40.3 bits (90), Expect = 0.57 Identities = 18/72 (25%), Positives = 34/72 (47%) Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 ++ + G P P++ W+KNG L D + + +K+ + I++ Y A+N Sbjct: 1198 MLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNL 1257 Query: 1651 AGTSSVEVTLKV 1662 G + E L+V Sbjct: 1258 QGEARCECRLEV 1269 Score = 39.9 bits (89), Expect = 0.75 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSI 789 E P +PL + V G + +L V G+P+P I+W KN + S ++ Sbjct: 1178 EAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTL 1237 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 I KP D G+Y +A N +G A + V P Sbjct: 1238 EIRKPCPF-DGGIYVCRATNLQGEARCECRLEVRVP 1272 Score = 37.9 bits (84), Expect = 3.0 Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 22/177 (12%) Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV----AVNREGEASLP 722 WL G+E+VPD I V+ +H L I +V E Y+ V A N + Sbjct: 576 WLKNGKELVPDSRIKVSHIGRVHK----LTIDDVTPADEADYSFVPEGFACNLSAKLHFM 631 Query: 723 IVLKIKTGEKEPPQVIEPL-----KSMIVRQGESVILSAQVVGNPRPTITWCK-----NN 772 V +EPP++ +++V G + L + G+P PT+ W K N Sbjct: 632 EVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNK 691 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 P + P + S + KK+ E ++ E + + ++ TVE +E+ Sbjct: 692 APARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETT----KDRSIFTVEGAEKED 744 Score = 36.3 bits (80), Expect = 9.2 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVY--TL 805 GE V L G PRP +TW K +P+ + T +I ++ + G Y T+ Sbjct: 987 GEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTV 1046 Query: 806 KAENSEGIAETSAVITVEEPT 826 + EN E A T + V++P+ Sbjct: 1047 RIENMEDKA-TLVLQVVDKPS 1066 >UniRef50_UPI000065FB77 Cluster: Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).; n=1; Takifugu rubripes|Rep: Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein). - Takifugu rubripes Length = 1393 Score = 138 bits (335), Expect = 1e-30 Identities = 108/447 (24%), Positives = 190/447 (42%), Gaps = 19/447 (4%) Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EISRESVTIEWKPPLD 1692 L + + ++ T + VT + + P P+ ++ E ++ V + WKPP Sbjct: 376 LTSKEKETFQVYGTSAPWTGQIIVTEEEPAEGIVPGRPLELQVTEATKNYVVLSWKPPAG 435 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 G LE Y +EK + W +V ++ + + L E Y FRV N G E Sbjct: 436 KG-LEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYSFRVRCCNSAGVGE 494 Query: 1752 ALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 + +E + LD+PS D SV ++W S ++ Y +E G Sbjct: 495 PSDPTEATTVGDKLDIPSAPGRVVPTRNTDT-SVVVSWEASRD--ARELVGYYIEGSIVG 551 Query: 1811 KK-WKXXXXXXXXXARI--QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 + W+ R L+ Y FR+ A N G S + + + + P+ Sbjct: 552 SQVWEPCNNKPVNGTRFICHGLTTGEKYVFRVRALNAAGLSQFSPESEPVEVKAAIASPT 611 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV----KGKSWTKIVTVGGSVH 1923 P V ES S+ L W +P S GG+ +T Y ++++ V GK W + S Sbjct: 612 PPYGITVLESVRDSMVLAWKQPTSIGGADVTGYFVDYREVVDGLPGK-WHEANVRAISER 670 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNI 1982 + + ++KE + F++ A N GV +P+ L + T+ P P L+IR V S+ Sbjct: 671 AYRVTDLKENRKYQFQVRAANIAGVGVPSLPSETFLCEEWTIAVPGPPHDLQIREVRSDS 730 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 ++ W P + G P+ G+ + ++ D + W V + I++L E T++ R Sbjct: 731 LVLLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKMFLKIKNLKEAETFVFR 790 Query: 2041 IYARNEIGLSEPLESDEPFKVIPGEGS 2067 + A+N+ G+ + E+ EP + G+ Sbjct: 791 VRAQNKAGVGKSSEATEPVSAVTKPGT 817 Score = 62.1 bits (144), Expect = 2e-07 Identities = 57/204 (27%), Positives = 96/204 (47%), Gaps = 17/204 (8%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL--PTK----SDGDTH 787 P VI+P +S V + + V L V G P P + W KNN + L P K S + H Sbjct: 20 PEFVIKP-RSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKIDSSYNIH 78 Query: 788 SITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEP--PLFINRFQEITV 844 S+ I K +D Y + A NS+G ++ ++V+ P E +++F Sbjct: 79 SLEINKCD-FEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDKFGVSFG 137 Query: 845 KEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 +E T+ L V PV P I WYR++ ++SPS+ ++ G+ L +++++ E Sbjct: 138 REGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDRATLTLSHLNKE- 196 Query: 900 DSGDYKCVASNSAGKSSHGARVTI 923 D G Y + +G ++ A V + Sbjct: 197 DEGLYTLRVTTKSGYETYSAYVFV 220 Score = 55.6 bits (128), Expect = 1e-05 Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 18/210 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI-SVAIESDMHMYC 692 P F KP++ V E + L C + P+P + W I P N I+S +++ Sbjct: 20 PEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKIDSSYNIHS 79 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE------PPQVIEPLKSMIV 746 L+I Y V A+N +GE S + +K G +++ Sbjct: 80 --LEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDKFGVSFG 137 Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVK 798 R+GE++ L VV P +P I W +++ P K GD ++T+ K + Sbjct: 138 REGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDRATLTLSHLNK-E 196 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEE 828 DEG+YTL+ G SA + V + E Sbjct: 197 DEGLYTLRVTTKSGYETYSAYVFVRDADAE 226 Score = 53.2 bits (122), Expect = 8e-05 Identities = 67/299 (22%), Positives = 124/299 (41%), Gaps = 35/299 (11%) Query: 651 ILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 ++L+C++ I E W G+EI DE++S E + L+I + K G Y Sbjct: 1099 VVLKCKVGNIKKETSALWYKDGQEIKADEHLSFT-EGVLK-----LEIAQISKKDAGVYE 1152 Query: 710 VVAVNREGEASLPIVLKIKTGEKEPPQVIE-------PLKSMIVRQGESVILSAQVVGNP 762 VV + G+ + + LK + + +V PLK QG + N Sbjct: 1153 VVLKDDRGKDTSTLNLKDQGFKDLMNEVFSFIANSSTPLKITSTDQGIRLYTFVSYY-ND 1211 Query: 763 RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 +TW N + + + G+ + I +P + KD G Y ++ + +G + Sbjct: 1212 LLQVTWQYKNSAIAFSDRIKSGVVGEQIFLQITEPTE-KDMGEYAIEFYDGKGGVRRTVE 1270 Query: 820 IT---VEEPTEENAEPPLFINRF-----------QEITVKEKGTIKLVARVTRNPVPSIT 865 +T E+ E +++ F +T++E + L ++ +PVP +T Sbjct: 1271 LTGQAFEDAYAEFQRLKIYLCFFTGRARVAGGLPDVVTIQEGKALSLTCNISGDPVPEVT 1330 Query: 866 WYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W +N++ I+ I F+ G+ +T V++ DSG Y + N G S V++ Sbjct: 1331 WLKNDKEITTDGHIILKFESGKFANFFVTGVNTS-DSGKYSILVKNKYGTESGDFTVSV 1388 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 498 FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 F++ ++ +P FV K R + V+ C V G+P P++ W++ I P + Sbjct: 8 FKRMNTDSLMHSPEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPG 67 Query: 558 MYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHG 608 Y D N+ +L I + ED + A N+ G S+ ++V+ P+S++G Sbjct: 68 KYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYG 121 Score = 50.0 bits (114), Expect = 7e-04 Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 28/219 (12%) Query: 1227 VTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 V WYK I+ + K+ + S +L I KC +D +Y +++K V Sbjct: 51 VVWYKNNVTIDPLANPGKYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASV 110 Query: 1284 V-----------EFPPKIVD-----YEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 V F IVD + RE + G V + Q + QP +W + Sbjct: 111 VVKNGPVSEYGITFQTHIVDKFGVSFGREGETMSLGCTVVIYPVLQGY-QPGIQWYRDDV 169 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---- 1382 ++ K A+LT+ + D G+Y LR+ G+ V + D + Sbjct: 170 LLSPSKWQHMHWSGDRATLTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFVRDADAEVEG 229 Query: 1383 PPGKP---NILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 PG P L+ + I + W +P G ++I+ Y V+ Sbjct: 230 APGSPLDVRCLDANKDYIIVTWKQPAVDGGNSILGYFVD 268 Score = 50.0 bits (114), Expect = 7e-04 Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 4/93 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN--ITKT 1436 P PP I E+ S S+ + W P G I + V+ +E D E W V N K Sbjct: 715 PGPPHDLQIREVRSDSLVLLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKM 774 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 I+NLK ++ FR A N+ + +SE TE Sbjct: 775 FLKIKNLKEAETFVFRVRAQNKAGVGKSSEATE 807 Score = 50.0 bits (114), Expect = 7e-04 Identities = 67/282 (23%), Positives = 110/282 (39%), Gaps = 38/282 (13%) Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--GNSKCTAIL 1189 K + W+KDG EI+ H+ T +G KL+I DAG Y + K T+ L Sbjct: 1109 KKETSALWYKDGQEIKADEHLSFT-EG-VLKLEIAQISKKDAGVYEVVLKDDRGKDTSTL 1166 Query: 1190 TVEEPSINFTL-RLPEFI------LVPANTD----AYLTVEIPDETLDVTWYKKKSVIED 1238 +++ + + FI L +TD Y V ++ L VTW K S I Sbjct: 1167 NLKDQGFKDLMNEVFSFIANSSTPLKITSTDQGIRLYTFVSYYNDLLQVTWQYKNSAIAF 1226 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYER- 1295 +++ ++ L I + TE D EY D K + VE+ F +++R Sbjct: 1227 SDRIKSGVVGEQIFLQITEPTEKDMGEYAIEFYDGKGGVRRTVELTGQAFEDAYAEFQRL 1286 Query: 1296 -------------------EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 I+ G ++L + P P W+ N K I H Sbjct: 1287 KIYLCFFTGRARVAGGLPDVVTIQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIIL 1346 Query: 1337 SIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 +S K A+ + V +D+G Y + ++N G + V++ Sbjct: 1347 KFESGKFANFFVTGVNTSDSGKYSILVKNKYGTESGDFTVSV 1388 Score = 49.2 bits (112), Expect = 0.001 Identities = 54/269 (20%), Positives = 107/269 (39%), Gaps = 31/269 (11%) Query: 1466 ETTEYYKVIK-ETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 E E++K + ++ + SP V KP + E + + L C G P P+V WY++ + Sbjct: 3 EHEEHFKRMNTDSLMHSPEFVIKPRSHTVWE-KQCVRLHCTVSGWPDPRVVWYKNNVTID 61 Query: 1524 TAK--ATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV---- 1572 Y+ N Y+ A N GE+ V ++ PV Sbjct: 62 PLANPGKYKIDSSYNIHSLEINKCDFEDTAQYRVSAMNSKGELSAFASVVVKNGPVSEYG 121 Query: 1573 ITISNEDIK----------QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 IT + + +G ++ V++G P + WY++ L K ++ Sbjct: 122 ITFQTHIVDKFGVSFGREGETMSLGCTVVIYPVLQGYQPG-IQWYRDDVLLSPSKWQHMH 180 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG----PVIMR-- 1676 + + + L + YT+ + +G + + V D ++ EG P+ +R Sbjct: 181 WSGDRATLTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFVRDADAEVEGAPGSPLDVRCL 240 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEK 1705 + +++ + + WK P DGG + Y +++ Sbjct: 241 DANKDYIIVTWKQPAVDGGNSILGYFVDR 269 Score = 47.2 bits (107), Expect = 0.005 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 9/137 (6%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGP---VIMREISRESVT 1684 R+ +LK + ++ + A+N AG S T + GP + +RE+ +S+ Sbjct: 673 RVTDLKENRKYQFQVRAANIAGVGVPSLPSETFLCEEWTIAVPGPPHDLQIREVRSDSLV 732 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 + WKPP+ G + + ++ E D W V + + I+ L E ++FRV Sbjct: 733 LLWKPPVYQGRDPINGFYVDMKEADAPEEAWRGVNNKATEKMFLKIKNLKEAETFVFRVR 792 Query: 1743 AQNPVGFSEALE-SEPI 1758 AQN G ++ E +EP+ Sbjct: 793 AQNKAGVGKSSEATEPV 809 Score = 46.0 bits (104), Expect = 0.011 Identities = 42/136 (30%), Positives = 62/136 (45%), Gaps = 12/136 (8%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFD 884 T+ P F+ + + TV EK ++L V+ P P + WY+NN I P + D Sbjct: 13 TDSLMHSPEFVIKPRSHTVWEKQCVRLHCTVSGWPDPRVVWYKNNVTIDPLANPGKYKID 72 Query: 885 GE-NI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEK--VTFVKHLQKS 937 NI L I D E D+ Y+ A NS G+ S A V + V + +TF H+ Sbjct: 73 SSYNIHSLEINKCDFE-DTAQYRVSAMNSKGELSAFASVVVKNGPVSEYGITFQTHIVDK 131 Query: 938 YET---EEGKTVILEC 950 + EG+T+ L C Sbjct: 132 FGVSFGREGETMSLGC 147 Score = 44.8 bits (101), Expect = 0.026 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 6/106 (5%) Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID---TTEW 1427 VE+ I P+PP +LE S+ + W +P + G + + Y V+Y+E+ +W Sbjct: 601 VEVKAAIAS-PTPPYGITVLESVRDSMVLAWKQPTSIGGADVTGYFVDYREVVDGLPGKW 659 Query: 1428 --ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 +V+ I++ + +LK N Y+F+ A N + S +E + Sbjct: 660 HEANVRAISERAYRVTDLKENRKYQFQVRAANIAGVGVPSLPSETF 705 Score = 41.9 bits (94), Expect = 0.19 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 6/93 (6%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYP-----RPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 V+K +G T+ C V YP +P I W+R ++ PS+ M++ D AT Sbjct: 129 VDKFGVSFGREGETMSLGCTVVIYPVLQGYQPGIQWYRDDVLLSPSKWQHMHWSGDR-AT 187 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + + ED G +T +G+ + + + V Sbjct: 188 LTLSHLNKEDEGLYTLRVTTKSGYETYSAYVFV 220 Score = 41.9 bits (94), Expect = 0.19 Identities = 38/161 (23%), Positives = 68/161 (42%), Gaps = 30/161 (18%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVM 1984 + ++ ++DE ++ + G + VR + A V P +PL++R + +N ++ Sbjct: 190 LSHLNKEDEGLYTLRVTTKSGYETYSAYVFVR-DADAEVEGAPGSPLDVRCLDANKDYII 248 Query: 1985 TSWGTPEWDGGAPLLGYNI--------AIR---DVTKT----------------MWMEVG 2017 +W P DGG +LGY + +R D TK+ W++ Sbjct: 249 VTWKQPAVDGGNSILGYFVDRSVGPAKTLRLEDDGTKSEAELFSSTCRCEVGTNHWIQCN 308 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 V +F + L E +Y+ R+ A N G+S P EP Sbjct: 309 DTPVKFARFPVTGLVEGRSYLFRVRAVNNSGMSHPSRVSEP 349 Score = 40.7 bits (91), Expect = 0.43 Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P + EG + L C + P P++ WL +EI D +I + ES + +T Sbjct: 1304 PDVVTIQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKF---ANFFVTG 1360 Query: 700 VKKFQEGTYTVVAVNREGEAS 720 V G Y+++ N+ G S Sbjct: 1361 VNTSDSGKYSILVKNKYGTES 1381 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650 +T I G P PEV W KN ++ D + + K + + + S S KY+I N Sbjct: 1317 LTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGKYSILVKNK 1376 Query: 1651 AGTSSVEVTLKVY 1663 GT S + T+ V+ Sbjct: 1377 YGTESGDFTVSVF 1389 Score = 39.1 bits (87), Expect = 1.3 Identities = 18/81 (22%), Positives = 33/81 (40%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G + C + G P P++TW + I + ++ A + V D+G ++ Sbjct: 1311 EGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGKYS 1370 Query: 583 CVAKNAAGFASSTTELIVEAP 603 + KN G S + V P Sbjct: 1371 ILVKNKYGTESGDFTVSVFIP 1391 Score = 38.3 bits (85), Expect = 2.3 Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 8/117 (6%) Query: 1384 PGKPNILEIDSSSIN---ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 PG+P L++ ++ N + W P G ++YY VE T W V + + Sbjct: 410 PGRPLELQVTEATKNYVVLSWKPPAGKGLEGVMYY-VEKCVSGTDSWQRVNTEIPVKSPR 468 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-PTVEKPLKNITT 1493 ++ +L SY FR N + + S+ TE V + I S P P +N T Sbjct: 469 FALFDLAEGKSYSFRVRCCNSAGVGEPSDPTEATTVGDKLDIPSAPGRVVPTRNTDT 525 Score = 38.3 bits (85), Expect = 2.3 Identities = 19/85 (22%), Positives = 40/85 (47%), Gaps = 3/85 (3%) Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGV 802 +++G+++ L+ + G+P P +TW KN+K + + K + + + D G Sbjct: 1309 IQEGKALSLTCNISGDPVPEVTWLKNDKEITTDGHIILKFESGKFANFFVTGVNTSDSGK 1368 Query: 803 YTLKAENSEGIAETSAVITVEEPTE 827 Y++ +N G ++V P E Sbjct: 1369 YSILVKNKYGTESGDFTVSVFIPDE 1393 Score = 37.5 bits (83), Expect = 4.0 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 6/108 (5%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435 LD PS PG+ +S+ + W+ + ++ Y +E + + W N + Sbjct: 508 LDIPSAPGRVVPTRNTDTSVVVSWEASRDARE--LVGYYIEGSIVGSQVWEPCNNKPVNG 565 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 T+ L T Y FR A+N +S S +E +V + I SPT Sbjct: 566 TRFICHGLTTGEKYVFRVRALNAAGLSQFSPESEPVEV--KAAIASPT 611 >UniRef50_Q6PDN3 Cluster: Myosin light chain kinase, smooth muscle; n=34; Euteleostomi|Rep: Myosin light chain kinase, smooth muscle - Mus musculus (Mouse) Length = 1941 Score = 138 bits (333), Expect = 2e-30 Identities = 109/433 (25%), Positives = 186/433 (42%), Gaps = 54/433 (12%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+ +S P F + + + +G TV+F C+V G P+P + WF + ++ + Y+D Sbjct: 395 SQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYED 454 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 L + D+ ++C A N+ G S + L+V+ P Sbjct: 455 GVSHHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPN------------------ 496 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 L P+FS K V EG D +L C + P P + WL G+ I +I Sbjct: 497 ------LAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICE 550 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT----GEKE----- 733 A +++H I + GTYT +A N G+ S + ++ GE+E Sbjct: 551 AGVAELH-------IQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSP 603 Query: 734 ------PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDG 784 P ++ L + V G V ++ QV GNP P + W + ++ + G Sbjct: 604 ARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKG 663 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 HS+ I + +D G YT +A NS G T AV+TV+EP + P FI++ + +T Sbjct: 664 GWHSLCIQEVFP-EDTGTYTCEAWNSAGEVRTRAVLTVQEP--HDGTQPWFISKPRSVTA 720 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGD 903 ++ + + +P P++ W R+ +S + E++ LV+ NV +G Sbjct: 721 TLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNV-QPWHAGQ 779 Query: 904 YKCVASNSAGKSS 916 Y+ + N G+ S Sbjct: 780 YEILLKNRVGECS 792 Score = 119 bits (287), Expect = 8e-25 Identities = 91/365 (24%), Positives = 155/365 (42%), Gaps = 27/365 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +P++Q V EG + C + IP+PD+ W +G + E I+ E + + Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE--KEPPQVIEPLKSMIVRQGES 751 +L+ + Y+ A N G+ S L + + P LK +V +G+ Sbjct: 462 LLR---ARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQD 518 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 +L V G P P +TW N +P++ + + + I + +D G YT AEN+ Sbjct: 519 FVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHI-QDALPEDRGTYTCLAENAM 577 Query: 812 GIAETSAVITVEE------------PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G SA +TV+E P P+F+ ++ V + + + +V+ N Sbjct: 578 GQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGN 637 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P + W + I SE G L I V E D+G Y C A NSAG+ A Sbjct: 638 PPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPE-DTGTYTCEAWNSAGEVRTRA 696 Query: 920 RVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEIS-GMDH 972 +T+ D + F+ +S G++V++ C + + W + + +S H Sbjct: 697 VLTVQEPHDGTQPWFISK-PRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGH 755 Query: 973 REIIQ 977 E++Q Sbjct: 756 FELLQ 760 Score = 104 bits (250), Expect = 2e-20 Identities = 72/241 (29%), Positives = 103/241 (42%), Gaps = 9/241 (3%) Query: 487 KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 K + +D V P +E AP F+ R +G+T +FE +V GYP PQ+TW R+ Sbjct: 14 KTSHSVDPSKVSSMPLTE----APAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRK 69 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 I F + +LVI V ED G +TC A N +G T EL VE S Sbjct: 70 GQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVELTVEGN-SM 128 Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 + V I PP F+ K V EG C++ P P + Sbjct: 129 KKRDQPVLSKASGFPGETRPSIWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVT 188 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 WL + P +S++ ++ M +L+I V + G YT + VN G+AS+ L Sbjct: 189 WLKGNVPLQPSARVSMSEKNGM----QILEIRGVTRDDLGVYTCMVVNGSGKASMSAELS 244 Query: 727 I 727 I Sbjct: 245 I 245 Score = 98.3 bits (234), Expect = 2e-18 Identities = 70/239 (29%), Positives = 109/239 (45%), Gaps = 30/239 (12%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 + + +APIF++ L DGS V QV G P P++ W I+ S+DF + Sbjct: 604 ARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFH-FEQK 662 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 +L I+EVFPED GT+TC A N+AG + L V+ P H Sbjct: 663 GGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEP---H--------------- 704 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 +G P F KP++ G +L+ C + P P + WL G + D Sbjct: 705 -------DGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFE 757 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEP 740 ++++ ++ VLK NV+ + G Y ++ NR GE S + L + + + PP+ EP Sbjct: 758 LLQNE-DVFTLVLK--NVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSRAPPRGREP 813 Score = 97.5 bits (232), Expect = 4e-18 Identities = 55/200 (27%), Positives = 92/200 (46%), Gaps = 1/200 (0%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+I+ + + +++ G V L +W+ K I++ +H K + LT Sbjct: 1259 PPQIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLT 1318 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405 I G Y L +EN G ++N+T++DKP PP G P +I SSS+ + W Sbjct: 1319 ILAARQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1378 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G S + Y VE + + W + T ++Q+L + Y+FR AVN S+ S Sbjct: 1379 YDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPS 1438 Query: 1466 ETTEYYKVIKETKIQSPTVE 1485 + +E V ++ + VE Sbjct: 1439 QESELTAVGEKPEEPKDEVE 1458 Score = 94.3 bits (224), Expect = 3e-17 Identities = 45/126 (35%), Positives = 72/126 (57%), Gaps = 1/126 (0%) Query: 486 KKLNEKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544 +KL + D F + +EE+ + P F + +R +GS +F+C++EGYP P++ WF Sbjct: 1806 EKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 1865 Query: 545 RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 + I+ S+ FQ+ YD+D +L+I +V +D +TC A N+ G A+ T ELIVE Sbjct: 1866 KDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1925 Query: 605 SDHGSE 610 G E Sbjct: 1926 EGEGEE 1931 Score = 77.4 bits (182), Expect = 4e-12 Identities = 49/176 (27%), Positives = 79/176 (44%), Gaps = 3/176 (1%) Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 QK + G+ + + G P W K +++ + + E S + I ++ H Sbjct: 1269 QKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLTILAARQEHCG 1328 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 YT+ N G+ +V L V DKP P G +I S+T+ W DGG + Y Sbjct: 1329 CYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1388 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756 +E + ++ W ++A ++ +Q L + EY FRV A N G SE + ESE Sbjct: 1389 NVEIWDTEDKVWKELATCRS--TSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESE 1442 Score = 69.7 bits (163), Expect = 8e-10 Identities = 78/411 (18%), Positives = 153/411 (37%), Gaps = 37/411 (9%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH-TKPSIDSKSASLT 1346 P+ + + G V + + P+P+ W + +++ + T+ D S L Sbjct: 402 PRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLC 461 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 + + D+ Y N+ G ++ + +PN+ + S ++ D Sbjct: 462 LLRARTRDSRKYSCTASNSLGQVSCSWSLLV-------DRPNLAQTAPSFSSVLKDSVVI 514 Query: 1407 TGNSTIIYYVVEYQEIDTTEWI----------SVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 G ++ V+ W+ S+ + IQ+ + A Sbjct: 515 EGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHIQDALPEDRGTYTCLAE 574 Query: 1457 NEVDISDASETTEYYKVIKETKIQ---SPTVEKPLKNITTEPNEDIE--------LTCIF 1505 N + S T + E + + SP KP+ I + D++ +T Sbjct: 575 NAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634 Query: 1506 GGVPQPKVTWYRDGKKLKTAK-ATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P+V W DG +++ ++ +E + Y C A+N GEV T Sbjct: 635 SGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 694 Query: 1562 SCVVGIQQKPVIT---ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK- 1617 V+ +Q+ T ++ +G L++ I G P P V W ++G L D Sbjct: 695 RAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSG 754 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + + E + +K ++ H+ +Y I N G S +V+L +++ PS+ Sbjct: 755 HFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSR 805 Score = 68.9 bits (161), Expect = 1e-09 Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 28/217 (12%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHS 788 E P I P +++ V++G + +V G P P +TW + + + + L T S Sbjct: 31 EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFS 90 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--------EPTEENAE--------- 831 + I ++ +D+G YT +A N G + + +TVE +P A Sbjct: 91 LVIHTVRE-EDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPS 149 Query: 832 -----PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 PP F + VKE + ++T P P +TW + N + PS ++ + Sbjct: 150 IWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNG 209 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 L I V + D G Y C+ N +GK+S A ++I Sbjct: 210 MQILEIRGVTRD-DLGVYTCMVVNGSGKASMSAELSI 245 Score = 64.9 bits (151), Expect = 2e-08 Identities = 52/195 (26%), Positives = 90/195 (46%), Gaps = 10/195 (5%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 G +P + ++P+ + + I +AQ G+ +P N +P + P K G+ S Sbjct: 1026 GNAKPTETLKPVGNTKPAETLKPIANAQPSGSLKPVT----NAQPAE--PQKPVGNAKSA 1079 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 KP K+E V +K + + + A + P E P+F + Q++ V E Sbjct: 1080 ETSKPAG-KEE-VKEVKNDVNCKKGQVGATGNEKRP-ESQGSAPVFKEKLQDVHVAEGEK 1136 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + L +V +P ++TW N + + ++ I +G + I E D G YKCVA Sbjct: 1137 LLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPE-DRGLYKCVAK 1195 Query: 910 NSAGKSSHGARVTID 924 NSAG++ +VT+D Sbjct: 1196 NSAGQAECSCQVTVD 1210 Score = 64.9 bits (151), Expect = 2e-08 Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 1/98 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E Q AP+F EKL+ H +G + +CQV P +TW +K ++ F + + Sbjct: 1114 ESQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTK-FIVLAQEG 1172 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + ++ I + PED G + CVAKN+AG A + ++ V+ Sbjct: 1173 SRFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVD 1210 Score = 64.5 bits (150), Expect = 3e-08 Identities = 93/418 (22%), Positives = 159/418 (38%), Gaps = 49/418 (11%) Query: 808 ENSEGIAETSAVITVEEPTEENAEP--PLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 ++S G + + +T P E E P F ++ Q V E T+K + V+ P P + Sbjct: 375 QSSLGGSVGNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVG 434 Query: 866 WYRNNEIISPSETITQNF-DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W+ + E IT+ + DG + L + + DS Y C ASNS G+ S + +D Sbjct: 435 WFLEGIPVRRREGITEVYEDGVSHHLCLLRARTR-DSRKYSCTASNSLGQVSCSWSLLVD 493 Query: 925 ----VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQE 978 + + K EG+ +L C T + + W N + I I E Sbjct: 494 RPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQ---FAHSICE 550 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET------------------I 1016 D G C+ ++ S + V+E Sbjct: 551 AGVAELHIQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIA 610 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ L D +V + + V+++ +V+W DG I+ ++ + FE++G L Sbjct: 611 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESED-FHFEQKGGWHSLC 669 Query: 1076 IRNTSVHDEGEYSCIL---RDESCTAEVTVVELP-----PEIITRLQNQKVNKGNKATFE 1127 I+ D G Y+C E T V V+ P P I++ ++ G Sbjct: 670 IQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLIS 729 Query: 1128 IELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + GD V W +DG + + S H +L + L + + AG+Y + N Sbjct: 730 CAIA-GDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKN 786 Score = 63.7 bits (148), Expect = 5e-08 Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 5/132 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P E L+ + V +GE ++L QV+ +P T+TW N K +K + +G S++I Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSI 1179 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTI 850 K +D G+Y A+NS G AE S +TV++ T EN + P +R + ++ Sbjct: 1180 EKALP-EDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGT 1238 Query: 851 KLVARVTRNPVP 862 + A V + P P Sbjct: 1239 ESDATVKKKPAP 1250 Score = 62.9 bits (146), Expect = 9e-08 Identities = 88/414 (21%), Positives = 161/414 (38%), Gaps = 45/414 (10%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHI 1071 + T P F + Q EV E E++ DV W +G ++ ++ + + G Sbjct: 398 ESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVS 457 Query: 1072 RKLYIRNTSVHDEGEYSCI----LRDESCTAEVTV-----VELPPEIITRLQNQKVNKGN 1122 L + D +YSC L SC+ + V + P + L++ V +G Sbjct: 458 HHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQ 517 Query: 1123 KATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC--- 1178 + A V W +G IQF++ I + +L I D +D G Y+C Sbjct: 518 DFVLRCSVQGTPAPRVTWLLNGQPIQFAHSI---CEAGVAELHIQDALPEDRGTYTCLAE 574 Query: 1179 -EVGNSKCTAILTVEE-----------------PSINFTLRLPEFILVPANTDAYLTVEI 1220 +G C+A +TV+E P L+ + V + +TV++ Sbjct: 575 NAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQV 634 Query: 1221 P-DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 + +V W + I+++E F +L I++ +D YTC ++ + Sbjct: 635 SGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 694 Query: 1280 K-VEVVEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK- 1332 + V V+ P P + R G V + P P W+ + + + K Sbjct: 695 RAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSG 754 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS--PP 1384 H + + +L +K V+ AG Y++ L+N G ++++ + + PS PP Sbjct: 755 HFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSRAPP 808 Score = 61.7 bits (143), Expect = 2e-07 Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 32/224 (14%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F P+ V EG+ E R+ PEP + W KG+ I ++ + S Sbjct: 33 PAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRF--LLDCGVRGTFS 90 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK------------------TGEKEP- 734 ++ I V++ +G YT A N G + + L ++ GE P Sbjct: 91 LV-IHTVREEDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPS 149 Query: 735 ------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS 788 P+ L +V++G+ S ++ G P P +TW K N P++ S + + Sbjct: 150 IWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNG 209 Query: 789 ITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 + IL+ + V D GVYT N G A SA +++ P +NA Sbjct: 210 MQILEIRGVTRDDLGVYTCMVVNGSGKASMSAELSI--PGLDNA 251 Score = 59.7 bits (138), Expect = 9e-07 Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 12/200 (6%) Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 IKV + + + + E+C + ++ +N +G +A V T +D P Sbjct: 1306 IKVENGESGSKLTILAARQEHCG-CYTLVVENKLGSRQAQ-----VNLTVVDKPDPPAGT 1359 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKLSIN 1832 I + S+ ++W+ S +GGS + Y VEI E K WK +Q L + Sbjct: 1360 PCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPD 1419 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPES 1891 Y+FR+ A N GTS P + +G+ P +P++ V VS+ + + + Sbjct: 1420 REYKFRVRAVNVYGTSEPSQESELTAVGE---KPEEPKDEVEVSDDDEKEPEVDYRTVTV 1476 Query: 1892 NGGSPITN-YIIEFKTVKGK 1910 N +++ Y IE + GK Sbjct: 1477 NTEQKVSDVYDIEERLGSGK 1496 Score = 57.2 bits (132), Expect = 5e-06 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 7/114 (6%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP + S+ + SW +DGG+ + YN+ I D +W E+ + Sbjct: 1353 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKEL--ATCRSTS 1410 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 FN++DL + Y R+ A N G SEP + E V GE EEP ++ EV Sbjct: 1411 FNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAV--GE---KPEEPKDEVEV 1459 Score = 52.8 bits (121), Expect = 1e-04 Identities = 62/246 (25%), Positives = 100/246 (40%), Gaps = 43/246 (17%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI--------- 680 +G P F +K + +V EG +LL+C++++ P + W G+ + + I Sbjct: 1116 QGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRF 1175 Query: 681 SVAIES----DMHMY------------CSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 SV+IE D +Y CS + + E T +R ++SLP V Sbjct: 1176 SVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPV 1235 Query: 725 L--------------KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 L K T PPQ+I+ + VR GE V L +V G T W K Sbjct: 1236 LGTESDATVKKKPAPKTPTKAAMPPQIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMK 1295 Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 K ++ + ++ +TIL ++ + G YTL EN G + +TV + + Sbjct: 1296 FRKQIQESEHIKVENGESGSKLTILAARQ-EHCGCYTLVVENKLGSRQAQVNLTVVDKPD 1354 Query: 828 ENAEPP 833 A P Sbjct: 1355 PPAGTP 1360 Score = 49.6 bits (113), Expect = 0.001 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P FSK + V EGS +C++ P+P++ W FK ++ + E+ I+ D Sbjct: 1829 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 1886 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 CS++ I++V + YT AVN GEA+ L ++T E+ Sbjct: 1887 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1926 Score = 49.2 bits (112), Expect = 0.001 Identities = 27/94 (28%), Positives = 41/94 (43%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 E P FI + + VKE T K RV P P +TW+R + I+ + Sbjct: 31 EAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFS 90 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 ++ + E D G Y C ASN +G +T++ Sbjct: 91 LVIHTVREEDKGKYTCEASNGSGARQVTVELTVE 124 Score = 46.8 bits (106), Expect = 0.007 Identities = 42/194 (21%), Positives = 78/194 (40%), Gaps = 13/194 (6%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA---TYENRXXXXX--XXX 1540 +P TE + ++ C G+P+P V W+ +G ++ + YE+ Sbjct: 407 QPQSQEVTE-GQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLCLLRA 465 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKV---GDEWLVTAVI 1596 Y C A N G+V S + + + + T + K V G ++++ + Sbjct: 466 RTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSV 525 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 +G P P V W NG ++ ++I + + + I++ YT A N G S Sbjct: 526 QGTPAPRVTWLLNGQPIQ--FAHSI-CEAGVAELHIQDALPEDRGTYTCLAENAMGQVSC 582 Query: 1657 EVTLKVYDKPSKPE 1670 T+ V +K + E Sbjct: 583 SATVTVQEKKGEGE 596 Score = 46.0 bits (104), Expect = 0.011 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 + AE E + S E+ P F +++ V E + ++ P P + Sbjct: 1803 INAEKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1862 Query: 865 TWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W+++++ I S ++D + N L+I++V + D Y C A NS G+++ A + + Sbjct: 1863 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELIV 1921 Query: 924 D 924 + Sbjct: 1922 E 1922 Score = 45.2 bits (102), Expect = 0.020 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYEN 1531 E++ +P ++ L+++ E + L C P VTW +GK LKT K A + Sbjct: 1114 ESQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGS 1173 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 R YKC+A N G+ E SC V + Sbjct: 1174 RFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTV 1209 Score = 44.8 bits (101), Expect = 0.026 Identities = 21/78 (26%), Positives = 35/78 (44%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G W + I G PPP+V W K L+ +++ K ++ I+ + R YT Sbjct: 168 KEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQILEIRGVTRDDLGVYT 227 Query: 1645 IEASNTAGTSSVEVTLKV 1662 N +G +S+ L + Sbjct: 228 CMVVNGSGKASMSAELSI 245 Score = 44.0 bits (99), Expect = 0.046 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 S+ S S+TL W +GGS + +Y +E + K W ++ T + ++++ Sbjct: 1363 SDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFN--VQDLLPDR 1420 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 E FR+ A N G S P SQ L P P +E+ Sbjct: 1421 EYKFRVRAVNVYGTSEP--SQESELTAVGEKPEEPKDEVEV 1459 Score = 43.2 bits (97), Expect = 0.081 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 6/127 (4%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F KLQD V E + +L+ ++ S+ A V W +G+ +K K + G + Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTK-FIVLAQEGSRFSVS 1178 Query: 1076 IRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131 I D G Y C+ ++ + C+ +VTV + T+ K + + + T Sbjct: 1179 IEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGT 1238 Query: 1132 KGDALVR 1138 + DA V+ Sbjct: 1239 ESDATVK 1245 Score = 42.7 bits (96), Expect = 0.11 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P+V W++ G + N + + + T + I ++ KYT EASN +G Sbjct: 56 VRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGAR 115 Query: 1655 SVEVTLKVY-DKPSKPEGPVIMR 1676 V V L V + K + PV+ + Sbjct: 116 QVTVELTVEGNSMKKRDQPVLSK 138 Score = 42.3 bits (95), Expect = 0.14 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164 P +++ +V +G+ A F+ ++ D V WFKD I+ S H Q+ D L Sbjct: 1831 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1890 Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192 I D DD +Y+C+ +G + CTA L VE Sbjct: 1891 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1922 Score = 42.3 bits (95), Expect = 0.14 Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 3/79 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG-- 1652 IEG P PEV+W+K+ + + + I E + + I ++ +KYT +A N+ G Sbjct: 1854 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1913 Query: 1653 TSSVEVTLKVYDKPSKPEG 1671 T + E+ ++ ++ EG Sbjct: 1914 TCTAELIVETMEEGEGEEG 1932 Score = 41.9 bits (94), Expect = 0.19 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 1/90 (1%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E PP+ T+L V +G F ++T + V W K +Q S + ++ Q Sbjct: 153 ECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQI 212 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 L+I DD G Y+C V N A ++ E Sbjct: 213 LEIRGVTRDDLGVYTCMVVNGSGKASMSAE 242 Score = 39.1 bits (87), Expect = 1.3 Identities = 21/85 (24%), Positives = 38/85 (44%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ + G + L + P W +N K +K K + + S++I+K D Sbjct: 1127 QDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPED 1186 Query: 1355 AGIYKLRLENNCGHADVEMNVTILD 1379 G+YK +N+ G A+ VT+ D Sbjct: 1187 RGLYKCVAKNSAGQAECSCQVTVDD 1211 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P + ++ + V +G + ++ G P P + W K+++ ++ D D + I Sbjct: 1831 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1890 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + D+ YT KA NS G A +A + VE E E Sbjct: 1891 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1930 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 5/103 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P +LQ+ V +G K + + ++ A V W +G ++ + I L +G + + I Sbjct: 1120 PVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSI 1179 Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204 +D G Y C G ++C+ +TV++ + + PE Sbjct: 1180 EKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPE 1222 >UniRef50_Q4RH24 Cluster: Chromosome 18 SCAF15072, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 18 SCAF15072, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1065 Score = 136 bits (330), Expect = 5e-30 Identities = 187/847 (22%), Positives = 313/847 (36%), Gaps = 56/847 (6%) Query: 462 LTEEKGWVPAQYLMDE--NNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPK 519 LT+E + LM+E N Y+ E+ + L + P F+ K Sbjct: 120 LTQEVRQPEVKELMEEPGNGYSALQNGACGEE-NGLSLNGDANDTSSDDKPRFLIKPLSL 178 Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPE 576 G F C++ G P P++ W + + S F + D L I Sbjct: 179 RVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISEQDGGWFQLRIYRTRMP 238 Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI-PPT 635 D G +TC A N G A + L+VEA S M+ + PP Sbjct: 239 DKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTSRLLPKHRSHKAALEPPV 298 Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 K K V EG C + P+P+I W K + + + I D Y + L Sbjct: 299 DVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVW--KKDGVPLEAGRRHLIFEDREGYYT-L 355 Query: 696 KITNVKKFQEGTYTVVAVNREG---EASLPIVLKI-----KTGEKEPPQVIEPL-KSMIV 746 K+ K+ G Y A N G + P+ ++ T E+ ++ L + + V Sbjct: 356 KVLYCKEKDTGLYVCAASNALGNHAQRCAPVRQRLGWKVQATLERRRGPIVRKLPRKLEV 415 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVY 803 +GE+ + +V N I W K+ + + KS G TH + + +D GV Sbjct: 416 MEGENAMFCVEVE-NDEEEIHWFKDGLQLHEMHQVILKSFGKTHILVFVNVAH-RDSGVV 473 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 T A S + + P AE + ++R + A +P + Sbjct: 474 TFVAGRSRTSSRLKVRASRHCPPICPAEATMDVDR-------PNSALLAWAPAPNSPTST 526 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK--CVASNSAGKSSHGA-R 920 + + S+ + F E D G+Y+ N G+S H Sbjct: 527 RSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVCCINKYGRSGHVEFP 586 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG- 979 + + +++ KS E EG+ Q S T++ W+ N ++ I Q Sbjct: 587 KVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAGTWFLNSAQLQPGGRFSIEQRHT 646 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE----VKEKDVAI 1035 + D + I S L V+ +F L D + V+ D + Sbjct: 647 KHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVRPVEVKF-SPLSDTDGNKRVETGDAIV 705 Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 L E++ A V W +DG+ + + + + G +R++ I++ G Y+C + Sbjct: 706 LYCEVSHPFAQVSWFKDGKELL-MTDDLNIQSEGKMRRVVIQSADASHAGVYTCETSGDI 764 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL----TKGDALVRWFKDGSEIQFSNH 1151 V V PP + ++++K + + L + DA V W+KDG EI S + Sbjct: 765 IRYNVEVAG-PPVEFCPVPEEELHKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSEN 823 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVP-- 1209 + L DG ++L I D DAG Y+C GN+ + + ++ + P ++V Sbjct: 824 VTLQADGTMRRLIIRSADTSDAGSYTCRAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPK 883 Query: 1210 --------ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 + D L E+ + V WYK +E++ LIS+ R L I T + Sbjct: 884 DDVVMERYVSEDIQLQCELSRSSGKVRWYKDGQPVEESPNLQLISEGPYRRLSILTGTVN 943 Query: 1262 DQCEYTC 1268 D EY C Sbjct: 944 DGGEYVC 950 Score = 119 bits (287), Expect = 8e-25 Identities = 153/708 (21%), Positives = 262/708 (37%), Gaps = 57/708 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ V K + +G +F C V G P+P+I W + ++ + ++ D + TL Sbjct: 297 PVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGRRHLIFEDREGYYTLK 356 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + +D G + C A NA L +H + Sbjct: 357 VLYCKEKDTGLYVCAASNA---------------LGNHAQRCAPVRQRLGWKVQATLERR 401 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 G P K P+ V EG + + C V E +I W G ++ + + H Sbjct: 402 RG--PIVRKLPRKLEVMEGENAMF-CVEVENDEEEIHWFKDGLQLHEMHQVILKSFGKTH 458 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +L NV G T VA G + LK++ PP + +M V + Sbjct: 459 ----ILVFVNVAHRDSGVVTFVA----GRSRTSSRLKVRASRHCPP-ICPAEATMDVDRP 509 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKS-----DGDTHSITILKPKKVKDEGVYT 804 S +L+ N PT T ++ + ++ +T + + V+ EG Y Sbjct: 510 NSALLAWAPAPNS-PTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYR 568 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 + + V E P + P P N + V E +++ Sbjct: 569 FRVCCINKYGRSGHV---EFPKVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG- 624 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 TW+ N+ + P + LVI D + +A+ + R + Sbjct: 625 -TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVR-PV 682 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXX 982 +V K + + + E G ++L C+ SH + W+ + KE+ D I EG+ Sbjct: 683 EV-KFSPLSDTDGNKRVETGDAIVLYCEVSHPFAQVSWFKDGKELLMTDDLNIQSEGKMR 741 Query: 983 XXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVK---EKDVAILEVE 1039 GV C + V EF ++ K E D +L Sbjct: 742 RVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLLCH 801 Query: 1040 INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 +++E A+V W +DG I P +N + G +R+L IR+ D G Y+C + S Sbjct: 802 VSAEDAEVTWYKDGCEIHPSEN-VTLQADGTMRRLIIRSADTSDAGSYTCRAGNNSMEFS 860 Query: 1100 VTVV--------ELPPEIITRLQNQKVNK---GNKATFEIELTKGDALVRWFKDGSEIQF 1148 V + PP +I ++ V + + EL++ VRW+KDG ++ Sbjct: 861 VNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSSGKVRWYKDGQPVEE 920 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196 S ++QL +G ++L I ++D GEY CE LTV++P + Sbjct: 921 SPNLQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKDPPV 968 Score = 92.3 bits (219), Expect = 1e-16 Identities = 179/865 (20%), Positives = 334/865 (38%), Gaps = 87/865 (10%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL-------PTK 781 + + +P +I+PL S+ V +GE S ++ G P P + W K+ K + + ++ Sbjct: 164 SSDDKPRFLIKPL-SLRVDRGEDAYFSCKLWGTPLPEVGWEKDGKKLNDIFESAHFSISE 222 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA----------- 830 DG + I + + + D+GVYT +A N G A AV+ VE E A Sbjct: 223 QDGGWFQLRIYRTR-MPDKGVYTCRATNCHGEALAGAVLLVEAVPERGASNMSSGGQSTS 281 Query: 831 -------------EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 EPP+ +++ ++ V E K VT P P I W ++ + Sbjct: 282 RLLPKHRSHKAALEPPVDVSKAKKFAVAEGKHAKFRCFVTGKPKPEIVWKKDGVPLEAGR 341 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH---------GARV--TIDVE 926 D E + E D+G Y C ASN+ G + G +V T++ Sbjct: 342 RHLIFEDREGYYTLKVLYCKEKDTGLYVCAASNALGNHAQRCAPVRQRLGWKVQATLERR 401 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTSHTVST-KWYHNKKEISGMDHREIIQE-GRXXXX 984 + V+ L + E EG+ + + + W+ + ++ M H+ I++ G+ Sbjct: 402 RGPIVRKLPRKLEVMEGENAMFCVEVENDEEEIHWFKDGLQLHEM-HQVILKSFGKTHIL 460 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKET--IPEFIRKLQDFEVKEKDVAILE--VEI 1040 D GV+ + TS+ L V+ + P +V + A+L Sbjct: 461 VFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEATMDVDRPNSALLAWAPAP 520 Query: 1041 NSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS---CILRDESC 1096 NS T+ ++ + + + ++ F + V EG Y C + Sbjct: 521 NSPTSTRSIFVVEMQEVGSQEWLKCFTSET-ATSAEVTGDGVQCEGNYRFRVCCINKYGR 579 Query: 1097 TAEVT---VVELPP--EIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151 + V VV L P +I L++ +V +G A F I+L+ A WF + +++Q Sbjct: 580 SGHVEFPKVVHLVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAGT-WFLNSAQLQPGGR 638 Query: 1152 IQLTIDGKKQKLKIYDCDL-DDAGEYSCEVGNSKCTAILTVEEPSINFT-LRLPEFILVP 1209 + K L I+ + +D E + + +A L V + F+ L + Sbjct: 639 FSIEQRHTKHSLVIHQTHMSEDKAEVTFIANGVRDSAPLHVRPVEVKFSPLSDTDGNKRV 698 Query: 1210 ANTDAY-LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 DA L E+ V+W+K + T+ + S+ K R ++I+ YTC Sbjct: 699 ETGDAIVLYCEVSHPFAQVSWFKDGKELLMTDDLNIQSEGKMRRVVIQSADASHAGVYTC 758 Query: 1269 VLLDAKSTTKLKVEV----VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 + + VEV VEF P V E ++ D +L+ + + W + Sbjct: 759 ET--SGDIIRYNVEVAGPPVEFCP--VPEEELHKSSMELDPVVLLCHVSAEDAEVTWYKD 814 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 I ++ D L I+ + +DAG Y R NN + +N+ + S Sbjct: 815 GCEIHPSENVTLQADGTMRRLIIRSADTSDAGSYTCRAGNN--SMEFSVNIRGGNVASSN 872 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLK 1444 +P ++ ++ + E + I + W + ++Q L Sbjct: 873 TEPPVMIVEPKDDVVM----ERYVSEDIQLQCELSRSSGKVRWYKDGQPVEESPNLQ-LI 927 Query: 1445 TNSSYRFRAYAVNEVD-----ISDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNED 1498 + YR + V+ + ++ + ++++ +K+ ++ + + +T E Sbjct: 928 SEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKDPPVRIISPSESELELTHVAPER 987 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLK 1523 +EL+C V P V W+RDG ++K Sbjct: 988 LELSCEISKVEAP-VRWFRDGLEVK 1011 Score = 73.7 bits (173), Expect = 5e-11 Identities = 104/466 (22%), Positives = 191/466 (40%), Gaps = 41/466 (8%) Query: 705 EGTYT--VVAVN---REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 EG Y V +N R G P V+ + G P++ LKS V +GE S Q+ Sbjct: 564 EGNYRFRVCCINKYGRSGHVEFPKVVHLVPG----PKIQNCLKSCEVAEGEDAHFSIQL- 618 Query: 760 GNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 + TW N+ +P + HS+ I + +D+ T A G+ + Sbjct: 619 -STTMAGTWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIAN---GVRD- 673 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 SA + V P E P + + + + I L V+ +P ++W+++ + + + Sbjct: 674 SAPLHVR-PVEVKFSPLSDTDGNKRVETGD--AIVLYCEVS-HPFAQVSWFKDGKELLMT 729 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + + +G+ +VI + D+ +G Y C S + + V + V + Sbjct: 730 DDLNIQSEGKMRRVVIQSADAS-HAGVYTCETSGDIIR--YNVEVAGPPVEFCPVPEEEL 786 Query: 937 SYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + E V+L C S WY + EI ++ + +G D G Sbjct: 787 HKSSMELDPVVLLCHVSAEDAEVTWYKDGCEIHPSENVTLQADGTMRRLIIRSADTSDAG 846 Query: 996 VIKCIVKDQETSTMLVVK--------ETIPEFIRKLQDFEVKEKDVAI---LEVEINSET 1044 C + + ++ P I + +D V E+ V+ L+ E++ + Sbjct: 847 SYTCRAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSS 906 Query: 1045 ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 V W +DG+ ++ N G R+L I +V+D GEY C +S ++TV + Sbjct: 907 GKVRWYKDGQPVEESPN-LQLISEGPYRRLSILTGTVNDGGEYVCESDGDSVFFQLTVKD 965 Query: 1105 LPPEIITRLQNQ-KVNKGNKATFEI--ELTKGDALVRWFKDGSEIQ 1147 P II+ +++ ++ E+ E++K +A VRWF+DG E++ Sbjct: 966 PPVRIISPSESELELTHVAPERLELSCEISKVEAPVRWFRDGLEVK 1011 Score = 65.7 bits (153), Expect = 1e-08 Identities = 80/382 (20%), Positives = 155/382 (40%), Gaps = 26/382 (6%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS-SSINI 1399 K+ L V + D+G+ + + +++ + P P + +++D +S + Sbjct: 456 KTHILVFVNVAHRDSGVVTFVAGRSRTSSRLKVRASRHCPPICPAEAT-MDVDRPNSALL 514 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTNSSYRFRAYAV 1456 W N+ ST +VVE QE+ + EW+ + T + + ++ +YRFR + Sbjct: 515 AWAPAPNSPTSTRSIFVVEMQEVGSQEWLKCFTSETATSAEVTGDGVQCEGNYRFRVCCI 574 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED----IELTCIFGGVPQPK 1512 N+ S E+ KV+ + P ++ LK+ ED I+L+ G Sbjct: 575 NKYG---RSGHVEFPKVVH--LVPGPKIQNCLKSCEVAEGEDAHFSIQLSTTMAG----- 624 Query: 1513 VTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKC-IAFNDHGEVETSCVVGIQQK 1570 TW+ + +L+ + + E R K + F +G V S + ++ Sbjct: 625 -TWFLNSAQLQPGGRFSIEQRHTKHSLVIHQTHMSEDKAEVTFIANG-VRDSAPLHVRPV 682 Query: 1571 PV--ITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 V +S+ D ++ + GD ++ + P +V W+K+G +L + NI ++ K Sbjct: 683 EVKFSPLSDTDGNKRVETGDAIVLYCEVSH-PFAQVSWFKDGKELLMTDDLNIQSEGKMR 741 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 + I+ SH+ YT E S +VEV + PE + + + V + Sbjct: 742 RVVIQSADASHAGVYTCETSGDIIRYNVEVAGPPVEFCPVPEEELHKSSMELDPVVLLCH 801 Query: 1689 PPLDDGGLELTKYAIEKHEPDN 1710 +D + K E H +N Sbjct: 802 VSAEDAEVTWYKDGCEIHPSEN 823 Score = 48.4 bits (110), Expect = 0.002 Identities = 51/225 (22%), Positives = 97/225 (43%), Gaps = 20/225 (8%) Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 ++L C V+ + ++ W G EI P EN+++ + M L I + G+YT Sbjct: 796 VVLLCH-VSAEDAEVTWYKDGCEIHPSENVTLQADGTMRR----LIIRSADTSDAGSYTC 850 Query: 711 VAVNREGEASLPI-VLKIKTGEKEPP-QVIEPLKSMIVRQGESVILSAQV-VGNPRPTIT 767 A N E S+ I + + EPP ++EP +++ + S + Q + + Sbjct: 851 RAGNNSMEFSVNIRGGNVASSNTEPPVMIVEPKDDVVMERYVSEDIQLQCELSRSSGKVR 910 Query: 768 WCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W K+ +PV+ P S+G ++IL V D G Y +++ + +TV++ Sbjct: 911 WYKDGQPVEESPNLQLISEGPYRRLSIL-TGTVNDGGEYVCESDGDSVFFQ----LTVKD 965 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 P P E+T ++L +++ P + W+R+ Sbjct: 966 PPVRIISPS---ESELELTHVAPERLELSCEISKVEAP-VRWFRD 1006 >UniRef50_P11799 Cluster: Myosin light chain kinase, smooth muscle; n=10; Euteleostomi|Rep: Myosin light chain kinase, smooth muscle - Gallus gallus (Chicken) Length = 1906 Score = 136 bits (330), Expect = 5e-30 Identities = 101/367 (27%), Positives = 166/367 (45%), Gaps = 27/367 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 GIPP F +P++ EG +I + ++ P+PD+ W +G I E I + E H Sbjct: 426 GIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTH- 484 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQVIEPLKSMIVRQ 748 C LK + G+Y+ A N G+ S +L +K E+ P LK V + Sbjct: 485 -CLWLKKACLG--DSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSE 541 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 G+ +L V G P P ITW N +P++ + + +T+ + +D+G+YT AE Sbjct: 542 GQDFVLQCYVGGVPVPEITWLLNEQPIQYAHSTFEAGVAKLTV-QDALPEDDGIYTCLAE 600 Query: 809 NSEGIAETSAVITV-EEPTEENAE-----------PPLFINRFQEITVKEKGTIKLVARV 856 N+ G A SA +TV E+ + + AE P+F+ ++ V + + + V Sbjct: 601 NNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEV 660 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + NP P I W N + I +E G L I V E D+G Y C A N G++ Sbjct: 661 SANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPE-DTGKYTCEAWNELGETQ 719 Query: 917 HGARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGM 970 A +T+ D + F+ +S G+ V++ C + + W+ + +EI+ Sbjct: 720 TQATLTVQEPQDGIQPWFISK-PRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPG 778 Query: 971 DHREIIQ 977 EI+Q Sbjct: 779 TGCEILQ 785 Score = 134 bits (325), Expect = 2e-29 Identities = 109/432 (25%), Positives = 194/432 (44%), Gaps = 56/432 (12%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E + P F + + +G ++F+ +V G P+P + WF++ IK + Q+ Y++D Sbjct: 423 EPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQI-YEED 481 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 L +++ D+G+++C A N G S++ L V+ P Sbjct: 482 GTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPK------------------- 522 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +E + P FS K V EG D +L+C + +P P+I WL ++ I A Sbjct: 523 -----VEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLN------EQPIQYA 571 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKE-------- 733 S + L + + +G YT +A N G A S + +K K K+ Sbjct: 572 -HSTFEAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAK 630 Query: 734 -----PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGD 785 P ++ L + V G VI++ +V NP P I W N K ++ + G+ Sbjct: 631 LNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGN 690 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 +S+ I + +D G YT +A N G +T A +TV+EP ++ P FI++ + +T Sbjct: 691 EYSLYI-QEVFPEDTGKYTCEAWNELGETQTQATLTVQEP--QDGIQPWFISKPRSVTAA 747 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDY 904 + + + +P P++ W+++ + I+P T + E+I L++ NV S +G Y Sbjct: 748 AGQNVLISCAIAGDPFPTVHWFKDGQEITPG-TGCEILQNEDIFTLILRNVQSR-HAGQY 805 Query: 905 KCVASNSAGKSS 916 + N G+ S Sbjct: 806 EIQLRNQVGECS 817 Score = 107 bits (257), Expect = 3e-21 Identities = 95/369 (25%), Positives = 156/369 (42%), Gaps = 27/369 (7%) Query: 468 WVPAQYLMDENNYT-QYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGST 526 W+ L D +Y+ + L ++P EE +AP F L+ +G Sbjct: 487 WLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEE--VAPCFSSVLKGCTVSEGQD 544 Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 +C V G P P+ITW +P Q ++ VA L +++ PED G +TC+A+ Sbjct: 545 FVLQCYVGGVPVPEITWLLNE---QPIQYAHSTFEA-GVAKLTVQDALPEDDGIYTCLAE 600 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646 N AG AS + ++ V+ S +E T A + + P F K V Sbjct: 601 NNAGRASCSAQVTVKEKKSSKKAEGT-----------QAAKLNKTFAPIFLKGLTDLKVM 649 Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 +GS +++ + A P P+I WL G+EI E+ E + Y L I V G Sbjct: 650 DGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFH--FEKKGNEYS--LYIQEVFPEDTG 705 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 YT A N GE L ++ + P I +S+ G++V++S + G+P PT Sbjct: 706 KYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPT 765 Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + W K+ + P + D ++ IL+ + + G Y ++ N G + + Sbjct: 766 VHWFKDGQEITPGTGCEILQNEDIFTL-ILRNVQSRHAGQYEIQLRNQVGECSCQVSLML 824 Query: 823 EEPTEENAE 831 E + AE Sbjct: 825 RESSASRAE 833 Score = 100 bits (239), Expect = 5e-19 Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 1/188 (0%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+I + + +++ G V L W+ K I++ ++ K S+ LT Sbjct: 1224 PPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLT 1283 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405 I + G Y L +EN G ++N+T++DKP PP G P +I SSS+ + W Sbjct: 1284 ISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1343 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G S + Y VE +W + T ++Q+L+ + Y+FR A N IS+ S Sbjct: 1344 YDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDLQADREYKFRVRAANVYGISEPS 1403 Query: 1466 ETTEYYKV 1473 + +E KV Sbjct: 1404 QESEVVKV 1411 Score = 93.9 bits (223), Expect = 4e-17 Identities = 65/228 (28%), Positives = 97/228 (42%), Gaps = 8/228 (3%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F R G+T +FE +V GYP PQITW+R + + + + + +L Sbjct: 27 APAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSL 86 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA----PLSDHGSEMTVXXXXXXXXXXX 624 VI+ V D+G +TC A N G T EL VE S S T Sbjct: 87 VIKGVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPVEH 146 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 I PP F+ KP V EG C++ P+P + W + +E ++ Sbjct: 147 RPSIWGESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNMFE 206 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 ++ + L+I NV+ G YT VN G+AS+ L ++ +K Sbjct: 207 KTGI----QYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQGPDK 250 Score = 89.8 bits (213), Expect = 7e-16 Identities = 101/433 (23%), Positives = 172/433 (39%), Gaps = 53/433 (12%) Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + EN G+ ++ EE E PP F +R Q + E IK ++V+ P P + Sbjct: 406 ETENRAGVRKS----VKEEKREPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVE 461 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W++ I E I Q ++ + + DSG Y C A N G++S +T+ Sbjct: 462 WFKEGVPIKTGEGI-QIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKR 520 Query: 926 EKVTFV----KHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEG 979 KV V + K EG+ +L+C + W N++ I + E Sbjct: 521 PKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQ---YAHSTFEA 577 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKET------------------IP 1017 D G+ C+ ++ S + VKE P Sbjct: 578 GVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAP 637 Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 F++ L D +V + I+ VE+++ +++W +G+ I+ ++ + FEK+G+ LYI Sbjct: 638 IFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETED-FHFEKKGNEYSLYI 696 Query: 1077 RNTSVHDEGEYSC----ILRDESCTAEVTVVE----LPPEIITRLQNQKVNKGNKATFEI 1128 + D G+Y+C L + A +TV E + P I++ ++ G Sbjct: 697 QEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISC 756 Query: 1129 ELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGN 1182 + GD V WFKDG EI ++ + L + + AG+Y +VG Sbjct: 757 AIA-GDPFPTVHWFKDGQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGE 815 Query: 1183 SKCTAILTVEEPS 1195 C L + E S Sbjct: 816 CSCQVSLMLRESS 828 Score = 88.6 bits (210), Expect = 2e-15 Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 4/189 (2%) Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P IT ED +K + G+ + A + G P W K +++ ++ I E +S + Sbjct: 1225 PQITQFPED--RKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKL 1282 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690 I K+ H YT+ N G+ +V L V DKP P G +I S+T+ W Sbjct: 1283 TISSTKQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1342 Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 DGG + Y +E +N+W + ++ +Q L + EY FRV A N G S Sbjct: 1343 SYDGGSAVQSYTVEIWNSVDNKWTDLTTCRS--TSFNVQDLQADREYKFRVRAANVYGIS 1400 Query: 1751 EALESEPIV 1759 E + +V Sbjct: 1401 EPSQESEVV 1409 Score = 86.6 bits (205), Expect = 7e-15 Identities = 38/113 (33%), Positives = 67/113 (59%), Gaps = 1/113 (0%) Query: 490 EKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 +K++ F + +EE+ + P F + + +GS +F+C++EGYP P++ W++ Sbjct: 1773 DKVENEDAFLEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQ 1832 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +K S+ FQ+ YD++ +L I EV +D +TC A N+ G A+ T EL+VE Sbjct: 1833 PVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEATCTAELLVE 1885 Score = 78.6 bits (185), Expect = 2e-12 Identities = 53/220 (24%), Positives = 94/220 (42%), Gaps = 24/220 (10%) Query: 1467 TTEYYKVIKETKIQ--SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 +T + +K K++ +P LK T +D L C GGVP P++TW + + ++ Sbjct: 511 STSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQY 570 Query: 1525 AKATYENRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQK------------- 1570 A +T+E Y C+A N+ G S V +++K Sbjct: 571 AHSTFEAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAK 630 Query: 1571 ------PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 P+ D+K G + ++T + P PE+IW NG +++ ++++ K Sbjct: 631 LNKTFAPIFLKGLTDLKVMD--GSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKK 688 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 + I+E+ + KYT EA N G + + TL V + Sbjct: 689 GNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQE 728 Score = 76.6 bits (180), Expect = 7e-12 Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 25/267 (9%) Query: 488 LNEKIDKLPVFEKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 + +K + P KPT + AP F EKL+ DG + +C++ P ++W Sbjct: 1061 IGKKAENKPAASKPTPPPSKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLD 1120 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE----- 601 + IK S+ + + + +L I +V PED G + C+A+NAAG A +++VE Sbjct: 1121 SKAIKSSKSI-VISQEGTLCSLTIEKVMPEDGGEYKCIAENAAGKAECACKVLVEDTSST 1179 Query: 602 ---APLSDHGSEMTVXXXXXXXXXXXXADILE----------GIPPTFSKKPKAQYVDEG 648 P + A + + PP ++ P+ + V G Sbjct: 1180 KAAKPAEKKTKKPKTTLPPVLSTESSEATVKKKPAPKTPPKAATPPQITQFPEDRKVRAG 1239 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 + L ++V W+ ++I EN + IE+ + S L I++ K+ G Y Sbjct: 1240 ESVELFAKVVGTAPITCTWMKFRKQI--QENEYIKIENAEN--SSKLTISSTKQEHCGCY 1295 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPP 735 T+V N+ G + L + + +PP Sbjct: 1296 TLVVENKLGSRQAQVNLTV-VDKPDPP 1321 Score = 69.7 bits (163), Expect = 8e-10 Identities = 89/411 (21%), Positives = 157/411 (38%), Gaps = 27/411 (6%) Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 KS + K E + PP+ + G ++ P+P+ EW IK + Sbjct: 415 KSVKEEKREPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEG 474 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNI 1389 + + + L +KK D+G Y N G +T+ +P P ++ Sbjct: 475 IQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTV-KRPKVEEVAPCFSSV 533 Query: 1390 LEIDSSS-----INICW----DEPENTG--NSTIIYYVVEYQEIDTTEWISVKNITKTQT 1438 L+ + S + C+ PE T N I Y E + ++V++ Sbjct: 534 LKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQYAHSTFEAGVAK-LTVQDALPEDD 592 Query: 1439 SIQN-LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 I L N++ R A V +S+ E + K K +P K L ++ Sbjct: 593 GIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGS 652 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYE---NRXXXXXXXXXXXXXXXYKCIAF 1553 + +T P P++ W +GK+++ T +E N Y C A+ Sbjct: 653 QVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAW 712 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----GDEWLVTAVIEGIPPPEVIWYKN 1609 N+ GE +T + +Q+ P I I + V G L++ I G P P V W+K+ Sbjct: 713 NELGETQTQATLTVQE-PQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKD 771 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 G ++ I E + ++ ++ H+ +Y I+ N G S +V+L Sbjct: 772 GQEITPGTGCEILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSL 822 Score = 64.9 bits (151), Expect = 2e-08 Identities = 72/324 (22%), Positives = 128/324 (39%), Gaps = 34/324 (10%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL------ 1279 DV W+K+ I+ E + + L ++K D Y+C + + T Sbjct: 459 DVEWFKEGVPIKTGEGIQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTV 518 Query: 1280 -KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 + +V E P + + G D L P P W++N + I+ T Sbjct: 519 KRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLNEQPIQYAHST---F 575 Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDSSS 1396 ++ A LT++ D GIY ENN G A VT+ +K S +++ + Sbjct: 576 EAGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTF 635 Query: 1397 INI----CWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVKNITKTQTSIQNLKTNSSYRF 1451 I D G+ I+ V W+ + K I +T+ K N + Sbjct: 636 APIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWLHNGKEIQETEDFHFEKKGN---EY 692 Query: 1452 RAYAVNEVDISDASE-TTEYYKVIKETKIQSP-TVEKPL-----------KNITTEPNED 1498 Y + EV D + T E + + ET+ Q+ TV++P +++T ++ Sbjct: 693 SLY-IQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQDGIQPWFISKPRSVTAAAGQN 751 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL 1522 + ++C G P P V W++DG+++ Sbjct: 752 VLISCAIAGDPFPTVHWFKDGQEI 775 Score = 64.1 bits (149), Expect = 4e-08 Identities = 96/461 (20%), Positives = 175/461 (37%), Gaps = 38/461 (8%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF 1286 VTW K ++ E+F + + L I+ D YTC ++++ + E+ Sbjct: 187 VTWTKGDIHLQQNERFNMFEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQ 246 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P D + TL +A + + ++ I K+ K T + ++ Sbjct: 247 GPDKTDTHAQPLCMPPKPTTLAT--KAIENSDFKQATSNGIAKELKSTSTELMVETKDRL 304 Query: 1347 IKKVENTDAGIYKLR-LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI----CW 1401 K E Y R ++ + E N L + P +L+ SS+I + Sbjct: 305 SAKKET----FYTSREAKDGKQGQNQEANAVPLQESRGTKGPQVLQKTSSTITLQAVKAQ 360 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 EP+ +T I Q D + T TQ + +L S R R N + Sbjct: 361 PEPKAEPQTTFIR-----QAEDRKRTVQPLMTTTTQEN-PSLTGQVSPRSRE-TENRAGV 413 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + + + +E P E +++ ++I+ G P+P V W+++G Sbjct: 414 RKSVKEEK-----REPLGIPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVP 468 Query: 1522 LKTAKA--TYENRXX--XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISN 1577 +KT + YE Y C AFN G+ TS ++ +++ V ++ Sbjct: 469 IKTGEGIQIYEEDGTHCLWLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAP 528 Query: 1578 --EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRI 1632 + + V G ++++ + G+P PE+ W N E +Y +T E + + + Sbjct: 529 CFSSVLKGCTVSEGQDFVLQCYVGGVPVPEITWLLN----EQPIQYAHSTFEAGVAKLTV 584 Query: 1633 KELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPSKPEG 1671 ++ YT A N AG + S +VT+K K EG Sbjct: 585 QDALPEDDGIYTCLAENNAGRASCSAQVTVKEKKSSKKAEG 625 Score = 63.3 bits (147), Expect = 7e-08 Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 11/152 (7%) Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 V D G+ KAEN ++ + P P F + Q+ V + + L R+ Sbjct: 1055 VVDGGIIGKKAENKPAASKPT-------PPPSKGTAPSFTEKLQDAKVADGEKLVLQCRI 1107 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + +P S++W +++ I S++I + +G L I V E D G+YKC+A N+AGK+ Sbjct: 1108 SSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTIEKVMPE-DGGEYKCIAENAAGKAE 1166 Query: 917 HGARVTI-DVEKVTFVKHLQKSYETEEGKTVI 947 +V + D K +K +T++ KT + Sbjct: 1167 CACKVLVEDTSSTKAAKPAEK--KTKKPKTTL 1196 Score = 62.1 bits (144), Expect = 2e-07 Identities = 85/403 (21%), Positives = 164/403 (40%), Gaps = 49/403 (12%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P+F + Q E E + +++ + DV W ++G IK + +E+ G L+ Sbjct: 429 PQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDG-THCLW 487 Query: 1076 IRNTSVHDEGEYSCIL---RDESCTAEVTVVELP------PEIITRLQNQKVNKGNKATF 1126 ++ + D G YSC R ++ T+ + V+ P P + L+ V++G F Sbjct: 488 LKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQD--F 545 Query: 1127 EIELTKGDALV---RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----E 1179 ++ G V W + IQ+++ T + KL + D +D G Y+C Sbjct: 546 VLQCYVGGVPVPEITWLLNEQPIQYAHS---TFEAGVAKLTVQDALPEDDGIYTCLAENN 602 Query: 1180 VGNSKCTAILTVEEPS------------INFTLRLPEFIL------VPANTDAYLTVEIP 1221 G + C+A +TV+E +N T P F+ V + +TVE+ Sbjct: 603 AGRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFA-PIFLKGLTDLKVMDGSQVIMTVEVS 661 Query: 1222 DETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 ++ W I++TE F + +L I++ +D +YTC + T+ + Sbjct: 662 ANPCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQ 721 Query: 1281 VEV-VEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 + V+ P P + R G +V + P P W + + I Sbjct: 722 ATLTVQEPQDGIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGC 781 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + + +L ++ V++ AG Y+++L N G ++++ + Sbjct: 782 EILQNEDIFTLILRNVQSRHAGQYEIQLRNQVGECSCQVSLML 824 Score = 61.3 bits (142), Expect = 3e-07 Identities = 65/249 (26%), Positives = 102/249 (40%), Gaps = 36/249 (14%) Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G +V R + SL + + E P P +++ V+ G + +V G P P Sbjct: 2 GDVKLVTSTRVSKTSLTLSPSVPA---EAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQ 58 Query: 766 ITWCKNNKPV-KALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETS----- 817 ITW +N P+ + D I L K V+ D G YT +A N G+ + + Sbjct: 59 ITWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGVQEGDSGKYTCEAANDGGVRQVTVELTV 118 Query: 818 ---------------------AVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 +V VE P+ PP F + + V+E T + + Sbjct: 119 EGNSLKKYSLPSSAKTPGGRLSVPPVEHRPSIWGESPPKFATKPNRVVVREGQTGRFSCK 178 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGK 914 +T P P +TW + + + +E F+ I+ L I NV D+G Y C NSAGK Sbjct: 179 ITGRPQPQVTWTKGDIHLQQNERFNM-FEKTGIQYLEIQNVQL-ADAGIYTCTVVNSAGK 236 Query: 915 SSHGARVTI 923 +S A +T+ Sbjct: 237 ASVSAELTV 245 Score = 59.7 bits (138), Expect = 9e-07 Identities = 60/233 (25%), Positives = 99/233 (42%), Gaps = 37/233 (15%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+ P+ V G+ E ++ PEP I W G + P+ + V S ++ Sbjct: 28 PAFTLPPRNIRVQLGATARFEGKVRGYPEPQITWYRNGHPL-PEGDHYVVDHSIRGIFSL 86 Query: 694 VLKITNVKKFQEGTYTVVAVNREG----------------EASLPIVLKIKTGE------ 731 V+K V++ G YT A N G + SLP K G Sbjct: 87 VIK--GVQEGDSGKYTCEAANDGGVRQVTVELTVEGNSLKKYSLPSSAKTPGGRLSVPPV 144 Query: 732 --------KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD 783 + PP+ ++VR+G++ S ++ G P+P +TW K + ++ + Sbjct: 145 EHRPSIWGESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNM 204 Query: 784 GDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEEP--TEENAEP 832 + I L+ + V+ D G+YT NS G A SA +TV+ P T+ +A+P Sbjct: 205 FEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKASVSAELTVQGPDKTDTHAQP 257 Score = 59.3 bits (137), Expect = 1e-06 Identities = 68/303 (22%), Positives = 123/303 (40%), Gaps = 33/303 (10%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKL 1163 +PP+ +R Q+ + ++G + F+ +++ K V WFK+G I+ IQ+ + L Sbjct: 427 IPPQFESRPQSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTHCL 486 Query: 1164 KIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFIL----VPANTDAY 1215 + L D+G YSC G + + +LTV+ P + +L V D Sbjct: 487 WLKKACLGDSGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFV 546 Query: 1216 LTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-- 1272 L + + ++TW + I+ T + V K L ++ +D YTC+ + Sbjct: 547 LQCYVGGVPVPEITWLLNEQPIQYAHS-TFEAGVAK--LTVQDALPEDDGIYTCLAENNA 603 Query: 1273 AKSTTKLKVEVVE------------------FPPKIVDYEREYRIKRGSDVTLLVDYQAF 1314 +++ +V V E F P + + ++ GS V + V+ A Sbjct: 604 GRASCSAQVTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSAN 663 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W+ N K I++ + SL I++V D G Y N G + Sbjct: 664 PCPEIIWLHNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQAT 723 Query: 1375 VTI 1377 +T+ Sbjct: 724 LTV 726 Score = 58.8 bits (136), Expect = 2e-06 Identities = 46/187 (24%), Positives = 82/187 (43%), Gaps = 9/187 (4%) Query: 1893 GGSPITNYIIEF-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 G +PIT ++F K ++ + KI S + I + K++ + + EN +G S Sbjct: 1250 GTAPITCTWMKFRKQIQENEYIKIENAENS-SKLTISSTKQEHCGCYTLVVENKLG-SRQ 1307 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + ++K P PP + S+ + SW +DGG+ + Y + I + Sbjct: 1308 AQVNLTVVDK----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDN 1363 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071 W ++ + FN++DL + Y R+ A N G+SEP + E KV + E Sbjct: 1364 KWTDL--TTCRSTSFNVQDLQADREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKE 1421 Query: 2072 EPGEQTE 2078 E E ++ Sbjct: 1422 EEAELSD 1428 Score = 58.4 bits (135), Expect = 2e-06 Identities = 43/202 (21%), Positives = 81/202 (40%), Gaps = 8/202 (3%) Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 N +IK+ + + + E+C + ++ +N +G +A V T +D P Sbjct: 1268 NEYIKIENAENSSKLTISSTKQEHCG-CYTLVVENKLGSRQAQ-----VNLTVVDKPDPP 1321 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKL 1829 I + S+ ++W+ S +GGS + Y VEI KW +Q L Sbjct: 1322 AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFNVQDL 1381 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 + Y+FR+ A N G S P + + +G+ + +S+ + + + Sbjct: 1382 QADREYKFRVRAANVYGISEPSQESEVVKVGEKQEEELKEEEAELSDDEGKETEVNYRTV 1441 Query: 1890 ESNGGSPITN-YIIEFKTVKGK 1910 N +++ Y IE + GK Sbjct: 1442 TINTEQKVSDVYNIEERLGSGK 1463 Score = 54.4 bits (125), Expect = 3e-05 Identities = 77/364 (21%), Positives = 141/364 (38%), Gaps = 47/364 (12%) Query: 936 KSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 +S E EG+ + + + S +W+ I + +I +E D Sbjct: 436 QSLEASEGQEIKFKSKVSGKPKPDVEWFKEGVPIKTGEGIQIYEEDGTHCLWLKKACLGD 495 Query: 994 VGVIKCIVKDQE----TSTMLVVK-----ETIPEFIRKLQDFEVKEKDVAILEVEINS-E 1043 G C + TS +L VK E P F L+ V E +L+ + Sbjct: 496 SGSYSCAAFNPRGQTSTSWLLTVKRPKVEEVAPCFSSVLKGCTVSEGQDFVLQCYVGGVP 555 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAE 1099 ++ W + + I+ + ++ + KL +++ D+G Y+C+ + SC+A+ Sbjct: 556 VPEITWLLNEQPIQYAHSTFE----AGVAKLTVQDALPEDDGIYTCLAENNAGRASCSAQ 611 Query: 1100 VTVVE------------------LPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWF 1140 VTV E P + L + KV G++ +E++ + W Sbjct: 612 VTVKEKKSSKKAEGTQAAKLNKTFAPIFLKGLTDLKVMDGSQVIMTVEVSANPCPEIIWL 671 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSI 1196 +G EIQ + G + L I + +D G+Y+C E+G ++ A LTV+EP Sbjct: 672 HNGKEIQETEDFHFEKKGNEYSLYIQEVFPEDTGKYTCEAWNELGETQTQATLTVQEPQD 731 Query: 1197 N---FTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + + P + A + ++ I D V W+K I ++ + T Sbjct: 732 GIQPWFISKPRSVTAAAGQNVLISCAIAGDPFPTVHWFKDGQEITPGTGCEILQNEDIFT 791 Query: 1253 LIIR 1256 LI+R Sbjct: 792 LILR 795 Score = 52.0 bits (119), Expect = 2e-04 Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 12/178 (6%) Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 +K S +++TS ++ P AE P F + I V+ T + +V P P I Sbjct: 4 VKLVTSTRVSKTSLTLSPSVP----AEAPAFTLPPRNIRVQLGATARFEGKVRGYPEPQI 59 Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 TWYRN + + + I LVI V E DSG Y C A+N G V + Sbjct: 60 TWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGV-QEGDSGKYTCEAANDGGVRQ--VTVEL 116 Query: 924 DVEKVTFVKH-LQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGR 980 VE + K+ L S +T G+ + + ++ W + + + +R +++EG+ Sbjct: 117 TVEGNSLKKYSLPSSAKTPGGRLSVPPVEHRPSI---WGESPPKFATKPNRVVVREGQ 171 Score = 50.0 bits (114), Expect = 7e-04 Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 20/162 (12%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITI 791 P E L+ V GE ++L ++ +P +++W ++K + K++ +G S+TI Sbjct: 1084 PSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTI 1143 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE--------PTEENAE------PPLFIN 837 K +D G Y AEN+ G AE + + VE+ P E+ + PP+ Sbjct: 1144 EKVMP-EDGGEYKCIAENAAGKAECACKVLVEDTSSTKAAKPAEKKTKKPKTTLPPVLST 1202 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 E TVK+K K + P P IT + + + E++ Sbjct: 1203 ESSEATVKKKPAPKTPPKAA-TP-PQITQFPEDRKVRAGESV 1242 Score = 49.6 bits (113), Expect = 0.001 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHI 1071 K T P F KLQD +V + + +L+ I+S+ A V W D + IK K+ + G + Sbjct: 1080 KGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKS-IVISQEGTL 1138 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE 1099 L I D GEY CI + + AE Sbjct: 1139 CSLTIEKVMPEDGGEYKCIAENAAGKAE 1166 Score = 47.6 bits (108), Expect = 0.004 Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 4/103 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSIT 790 PPQ+ + + VR GESV L A+VVG T TW K K ++ + ++ ++ +T Sbjct: 1224 PPQITQFPEDRKVRAGESVELFAKVVGTAPITCTWMKFRKQIQENEYIKIENAENSSKLT 1283 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 I K+ + G YTL EN G + +TV + + A P Sbjct: 1284 ISSTKQ-EHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTP 1325 Score = 47.6 bits (108), Expect = 0.004 Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 3/102 (2%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P F+K V EGS +C++ P+P++ W +K ++ V E+ I+ D Sbjct: 1792 VKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMW-YKDDQPV-KESRHFQIDYDEEGN 1849 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 CS L I+ V + YT AVN GEA+ L ++T KE Sbjct: 1850 CS-LTISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMGKE 1890 Score = 47.2 bits (107), Expect = 0.005 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 3/79 (3%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAG-- 1652 IEG P PEV+WYK+ ++ + + I E+ + + I E+ +KYT +A N+ G Sbjct: 1817 IEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLTISEVCGDDDAKYTCKAVNSLGEA 1876 Query: 1653 TSSVEVTLKVYDKPSKPEG 1671 T + E+ ++ K + EG Sbjct: 1877 TCTAELLVETMGKEGEGEG 1895 Score = 46.8 bits (106), Expect = 0.007 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 12/135 (8%) Query: 1828 KLSINTTYQ-----FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 KL+I++T Q + + N++G+ + +T+ PP+ S+ S S+ Sbjct: 1281 KLTISSTKQEHCGCYTLVVENKLGSRQAQVN---LTVVDKPDPPAGTP--CASDIRSSSL 1335 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 TL W +GGS + +Y +E WT + T + +++++ E FR+ A Sbjct: 1336 TLSWYGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRSTSFN--VQDLQADREYKFRVRA 1393 Query: 1943 ENTVGVSLPTESQSV 1957 N G+S P++ V Sbjct: 1394 ANVYGISEPSQESEV 1408 Score = 46.4 bits (105), Expect = 0.009 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P++ WY+NG+ L Y + + + IK ++ S KYT EA+N G Sbjct: 51 VRGYPEPQITWYRNGHPLPEGDHYVVDHSIRGIFSLVIKGVQEGDSGKYTCEAANDGGVR 110 Query: 1655 SVEVTLKV 1662 V V L V Sbjct: 111 QVTVELTV 118 Score = 46.4 bits (105), Expect = 0.009 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 12/141 (8%) Query: 1254 IIRKCTEDDQ-CEYTCVLLDA-----KSTTKLKVEVVEFPPK------IVDYEREYRIKR 1301 +++K ++D+ CE+ C ++D K+ K PP + ++ ++ Sbjct: 1038 VVKKEEKNDRKCEHGCAVVDGGIIGKKAENKPAASKPTPPPSKGTAPSFTEKLQDAKVAD 1097 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 G + L + P + W ++SK IK K S + SLTI+KV D G YK Sbjct: 1098 GEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTIEKVMPEDGGEYKCI 1157 Query: 1362 LENNCGHADVEMNVTILDKPS 1382 EN G A+ V + D S Sbjct: 1158 AENAAGKAECACKVLVEDTSS 1178 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Query: 822 VEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 +EE EE P F ++ V E + ++ P P + WY++++ + S Sbjct: 1782 LEEVAEEKPHVKPYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQ 1841 Query: 881 QNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 ++D E N L I+ V + D Y C A NS G+++ A + ++ Sbjct: 1842 IDYDEEGNCSLTISEVCGD-DDAKYTCKAVNSLGEATCTAELLVE 1885 Score = 42.7 bits (96), Expect = 0.11 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 2/82 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 I G P P+V W K L+ ++ +N+ K + I+ ++ + + YT N+AG +S Sbjct: 179 ITGRPQPQVTWTKGDIHLQQNERFNMFEKTGIQYLEIQNVQLADAGIYTCTVVNSAGKAS 238 Query: 1656 V--EVTLKVYDKPSKPEGPVIM 1675 V E+T++ DK P+ M Sbjct: 239 VSAELTVQGPDKTDTHAQPLCM 260 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P +LQ+ KV G K + ++ A V W D I+ S I ++ +G L I Sbjct: 1084 PSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTLCSLTI 1143 Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195 +D GEY C G ++C + VE+ S Sbjct: 1144 EKVMPEDGGEYKCIAENAAGKAECACKVLVEDTS 1177 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164 P + + +V +G+ A F+ ++ D V W+KD ++ S H Q+ D + L Sbjct: 1794 PYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLT 1853 Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192 I + DD +Y+C+ +G + CTA L VE Sbjct: 1854 ISEVCGDDDAKYTCKAVNSLGEATCTAELLVE 1885 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 3/97 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSITILK 793 P + + M V +G + ++ G P P + W K+++PVK + + D D L Sbjct: 1794 PYFTKTILDMEVVEGSAARFDCKIEGYPDPEVMWYKDDQPVKESRHFQIDYDEEGNCSLT 1853 Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 +V D+ YT KA NS G A +A + VE +E Sbjct: 1854 ISEVCGDDDAKYTCKAVNSLGEATCTAELLVETMGKE 1890 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 1/90 (1%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E PP+ T+ V +G F ++T + V W K +Q + + Q Sbjct: 153 ESPPKFATKPNRVVVREGQTGRFSCKITGRPQPQVTWTKGDIHLQQNERFNMFEKTGIQY 212 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 L+I + L DAG Y+C V NS A ++ E Sbjct: 213 LEIQNVQLADAGIYTCTVVNSAGKASVSAE 242 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 4/96 (4%) Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXX 1536 +K +P+ + L++ E + L C P V+W D K +K++K+ ++ Sbjct: 1079 SKGTAPSFTEKLQDAKVADGEKLVLQCRISSDPPASVSWTLDSKAIKSSKSIVISQEGTL 1138 Query: 1537 XXXXXX----XXXXXYKCIAFNDHGEVETSCVVGIQ 1568 YKCIA N G+ E +C V ++ Sbjct: 1139 CSLTIEKVMPEDGGEYKCIAENAAGKAECACKVLVE 1174 >UniRef50_A7RGL4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 316 Score = 136 bits (328), Expect = 8e-30 Identities = 91/318 (28%), Positives = 149/318 (46%), Gaps = 18/318 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 PIF +K++ G V+FE QVEG P P +T+ R++ I + + +++ + L Sbjct: 1 PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFVLT 60 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-----DHGS-EMTVXXXXXXXXXX 623 IR PEDAG + C+A N AG +S L VE L+ D G+ + V Sbjct: 61 IRNTRPEDAGEYQCIAVNGAGEVTSKGYLHVEEELTIPQFIDMGTYKCQVRNDLGRTSTS 120 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +I+ P F +K V EG E R+ P P++ W I+ ++ + Sbjct: 121 AHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWYHGSNRILDEDRFEIE 180 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG------EKEPPQV 737 + Y L + V + G Y +AVN+ G+++ L++ E E P + Sbjct: 181 SVKETGYYS--LTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNERQFAPEFETEEPTI 238 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKP 794 ++ L+ + +GE++ + +V G P PTITW K+ + T DGD ++TI + Sbjct: 239 LQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDGDVCTLTI-RD 297 Query: 795 KKVKDEGVYTLKAENSEG 812 K+ DEG+Y A+NS G Sbjct: 298 VKLGDEGIYRCNAKNSSG 315 Score = 74.9 bits (176), Expect = 2e-11 Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 12/216 (5%) Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 GTY N G S L I + P+ E L + V +G+ +V G P P Sbjct: 104 GTYKCQVRNDLGRTSTSAHLNIIVATR--PEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161 Query: 766 ITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W + + + + + +S+T+ + + +D G+Y A N G + A + Sbjct: 162 VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQ-EDAGMYKCIAVNKAGKSTCRADL 220 Query: 821 TVEE---PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 V E E E P + R Q + E IK+ RV+ P P+ITW ++ + Sbjct: 221 EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDN 280 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 I FDG+ L I +V D G Y+C A NS+G Sbjct: 281 RIKTYFDGDVCTLTIRDVKLG-DEGIYRCNAKNSSG 315 Score = 68.5 bits (160), Expect = 2e-09 Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 1/87 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E ++ P +++L+P T +G ++ EC+V G P P ITW + + + Y+D D Sbjct: 230 EFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNRIKTYFDGD 289 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAG 590 V TL IR+V D G + C AKN++G Sbjct: 290 -VCTLTIRDVKLGDEGIYRCNAKNSSG 315 Score = 64.5 bits (150), Expect = 3e-08 Identities = 61/212 (28%), Positives = 86/212 (40%), Gaps = 21/212 (9%) Query: 993 DVGVIKCIVKDQ--ETST---MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSET-AD 1046 D+G KC V++ TST + ++ T PEF KL EV E D A EV + + Sbjct: 102 DMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161 Query: 1047 VVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVT 1101 V W I+ + + + K L + D G Y CI +++ C A++ Sbjct: 162 VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLE 221 Query: 1102 VVELP---------PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNH 1151 V E P I+ RLQ +G E ++ K + + W KDG N Sbjct: 222 VNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDNR 281 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 I+ DG L I D L D G Y C NS Sbjct: 282 IKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNS 313 Score = 57.6 bits (133), Expect = 4e-06 Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 18/166 (10%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G Y + N G TSA + + T P F + ++ V E K RV Sbjct: 102 DMGTYKCQVRNDLGRTSTSAHLNIIVATR-----PEFKEKLTKVEVTEGDRAKFEVRVKG 156 Query: 859 NPVPSITWYR-NNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P + WY +N I+ ++ L + V E D+G YKC+A N AGKS+ Sbjct: 157 YPYPEVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQE-DAGMYKCIAVNKAGKST 215 Query: 917 HGARVTI---------DVEKVTFVKHLQKSYETEEGKTVILECQTS 953 A + + + E+ T ++ LQ +T EG+ + +EC+ S Sbjct: 216 CRADLEVNERQFAPEFETEEPTILQRLQ-PVDTIEGEAIKMECRVS 260 Score = 56.0 bits (129), Expect = 1e-05 Identities = 57/215 (26%), Positives = 84/215 (39%), Gaps = 19/215 (8%) Query: 899 IDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTV 956 ID G YKC N G++S A + I V K E EG E + Sbjct: 101 IDMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYP 160 Query: 957 STKWYHNKKEISGMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCI-VKDQETSTM---L 1010 +WYH I D EI ++E D G+ KCI V ST L Sbjct: 161 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 220 Query: 1011 VVKET--IPEF-------IRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKK 1060 V E PEF +++LQ + E + +E ++ + + W +DG ++ Sbjct: 221 EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDG-LVFLTD 279 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 N+ G + L IR+ + DEG Y C ++ S Sbjct: 280 NRIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSS 314 Score = 52.0 bits (119), Expect = 2e-04 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 2/125 (1%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 YKC ND G TS + I + K + GD ++G P PEV WY Sbjct: 106 YKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPEVEWY 165 Query: 1608 KNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 N++ ++ + I + ++T + + E+ + + Y A N AG S+ L+V ++ Sbjct: 166 HGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLEVNER 225 Query: 1666 PSKPE 1670 PE Sbjct: 226 QFAPE 230 Score = 46.8 bits (106), Expect = 0.007 Identities = 37/172 (21%), Positives = 72/172 (41%), Gaps = 6/172 (3%) Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS--T 1411 D G YK ++ N+ G ++ I+ P K + +++ + + E G Sbjct: 102 DMGTYKCQVRNDLGRTSTSAHLNIIVATRPEFKEKLTKVEVTEGDRAKFEVRVKGYPYPE 161 Query: 1412 IIYYVVEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +Y + +D E SVK ++ + + ++ AVN+ S E Sbjct: 162 VEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADLE 221 Query: 1470 YYK--VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 + E + + PT+ + L+ + T E I++ C G P+P +TW +DG Sbjct: 222 VNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDG 273 Score = 46.0 bits (104), Expect = 0.011 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 13/155 (8%) Query: 1226 DVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKV 1281 +V WY + I D ++F + + + +L + + ++D Y C+ ++ KST + + Sbjct: 161 EVEWYHGSNRILDEDRFEIESVKETGYYSLTVGEVVQEDAGMYKCIAVNKAGKSTCRADL 220 Query: 1282 EVVE--FPPKIVDYEREY--RIK-----RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 EV E F P+ E R++ G + + P+P W+ + + Sbjct: 221 EVNERQFAPEFETEEPTILQRLQPVDTIEGEAIKMECRVSGKPEPTITWLKDGLVFLTDN 280 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 K D +LTI+ V+ D GIY+ +N+ G Sbjct: 281 RIKTYFDGDVCTLTIRDVKLGDEGIYRCNAKNSSG 315 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/96 (26%), Positives = 51/96 (53%), Gaps = 4/96 (4%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIEL 890 P+F + + + + ++ +V PVP++T++R +E I +I + +G + L Sbjct: 1 PIFGQKMKNVEGRIGEDVRFEIQVEGTPVPAVTFHRESEQIYDGGRYSIVEEENGLFV-L 59 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 I N E D+G+Y+C+A N AG+ + + ++ E Sbjct: 60 TIRNTRPE-DAGEYQCIAVNGAGEVTSKGYLHVEEE 94 >UniRef50_A2CEC7 Cluster: Novel protein similar to Down syndrome cell adhesion molecule; n=1; Danio rerio|Rep: Novel protein similar to Down syndrome cell adhesion molecule - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1904 Score = 135 bits (327), Expect = 1e-29 Identities = 208/1058 (19%), Positives = 399/1058 (37%), Gaps = 109/1058 (10%) Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V+ P I+ + ++V G++ + + RW +D S ++ + ++ G Sbjct: 51 VDSAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPLESDSRYHQSVSG--- 107 Query: 1162 KLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLT 1217 L I DAG Y CEV GN+K L V++P V + + + Sbjct: 108 -LLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCS 166 Query: 1218 VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 V DE D+TWY+ I I+ + L++ + D Y C + K +T Sbjct: 167 VTGSDE-FDITWYRNAEKIYQGINVR-ITGINNENLVMEGMAKSDGGAYQCFARNGKMST 224 Query: 1278 KLKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHT 1334 + V+VV + PKI+ E + ++L+ + P P W ++ +IK H Sbjct: 225 QDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHR 284 Query: 1335 KPSIDSKSAS----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 I + L + + +D G+Y+ N+ G + + + S N+ Sbjct: 285 MDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKNVT 344 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 I G T I+ + + +W N+ + + N + + Sbjct: 345 AI--------------AGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNHRQRAFENNGTLK 390 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSP---TVEKP--LKNITTEP---NEDIELT 1502 ++ V SD E T Y V E +I TV+ P +++ ++ + + + Sbjct: 391 -----LSNVQNSDEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQRVFIP 445 Query: 1503 CIF--GGVPQPKVTWYRDGKKLKTAKA-TYEN---RXXXXXXXXXXXXXXXYKCIAFNDH 1556 C+ G +P +TW++DG+ + + T +N Y CIA N+ Sbjct: 446 CVVISGDLPM-SITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEA 504 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLEN 1615 VE S + ++ P + +D Q G + +G P P ++W + G + Sbjct: 505 AAVEHSIQLIVKVPPHFEVQPKD--QDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQ 562 Query: 1616 DKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPS 1667 + + + + ++ IK + + Y + SN G + S+ +T+K+ + Sbjct: 563 FQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMIT 622 Query: 1668 KPEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIEKH--EPDNNRWI-KVADV-DR 1721 + ++ S T + P+ ++ E H PD +R++ V +V D Sbjct: 623 SYPNTTRAEQGHMTEMSCTAHGEKPIK------VRWEKESHIINPDMSRYVVTVKEVGDE 676 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 + T I F IA N G + + ++++ D P + + Sbjct: 677 VISTLQILHTVREDSGFFSCIAINSYGEDKGIIQ--LIVQDRPDPPEVEIRE-----VKD 729 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQ 1836 ++ + W +G SPI Y + K + W ++ + +I +TY Sbjct: 730 RTIALRWTMGF-DGNSPITGYDINYKNKSASWASSQMTKDVSPQLNQATIIELHPASTYN 788 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GG 1894 R++A+N+IG S P +++TI PP P++ + +S+ + + W P + Sbjct: 789 IRMFAKNQIGESRP---SNELTITTDEAPPDGAPQDVQLEAISSQGIKVTWKPPHKHLQN 845 Query: 1895 SPITNYII---EFKTVKGKSWTKI-VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 I +Y + EF T + I V G + ++N+K+ + R+ A N G+ Sbjct: 846 GLIRSYQVCYREFGTGGSPQYNTINVDTTGDIETLTLDNLKKYTQYEVRVQAANRAGMG- 904 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT-PEWDGGAPLLGYNIAI-RDV 2008 PT S+ + + VPS P + + SW P+ LLGY + ++ Sbjct: 905 PT-SEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANL 963 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSH 2068 E+ + + L + Y I++ A G + + S++ + Sbjct: 964 PDGELGEIRNITTTKPSLELERLEKYTNYSIQVLAFTRAG--DGVRSEQIYT------RT 1015 Query: 2069 ADEEPGEQTEVXXXXXXXXXXXXXWLREHNMDADIRSY 2106 ++ PG V WL H ++ IR Y Sbjct: 1016 KEDVPGPPAGVKAAASTSSVVFVSWLPPHKLNGIIRKY 1053 Score = 119 bits (286), Expect = 1e-24 Identities = 201/876 (22%), Positives = 342/876 (39%), Gaps = 93/876 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L C+ P P WL +N + +S H S L I + G+ Sbjct: 69 GHRVELPCKASGHPPPRYRWL--------RDNSPLESDSRYHQSVSGLLIEATRPSDAGS 120 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y N G A + L +K K V+ P K + G V L V G+ IT Sbjct: 121 YVCEVWNSFGNAKVVGRLVVKQPLKA---VVSPRK-VRGSVGSQVSLFCSVTGSDEFDIT 176 Query: 768 WCKN-NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W +N K + + + G + +++ D G Y A N + + + +E+ T Sbjct: 177 WYRNAEKIYQGINVRITGINNENLVMEGMAKSDGGAYQCFARNGKMSTQDLVQVVLEDGT 236 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--IISPSETITQNFD 884 P ++ F E V I LV V P+P++TW +++ I + + + Sbjct: 237 ------PKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIIT 290 Query: 885 GENIELVITNVD-SEI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 E L NV +++ D G Y+C +NSAG S+ AR I+V ++ + K+ Sbjct: 291 TEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQAR--INVRGPASIRPM-KNVTAIA 347 Query: 943 GKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G+ + C+ S KWY + + +HR+ E D G C Sbjct: 348 GRDTYIHCRIIGYPYYSIKWYKD-SNLLPFNHRQRAFENN-GTLKLSNVQNSDEGEYTCY 405 Query: 1001 V---KDQETSTMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEINSE-TADVVWERDGE 1054 V +++ + V +P I+ Q + ++ V I V I+ + + W +DG Sbjct: 406 VLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQR-VFIPCVVISGDLPMSITWHKDGR 464 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIIT 1111 I + L I N S G Y+CI R+E+ E + +V++PP Sbjct: 465 PINASLG-VTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEV 523 Query: 1112 RLQNQKVNKGNKATFEIELTKGDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQKLK---- 1164 + ++Q G T KG+ + + W G+ + I L + Q L+ Sbjct: 524 QPKDQDGIYGKSVTLNCS-AKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSL 582 Query: 1165 -IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT----DAYLT-- 1217 I +DAG Y C+V N I S+ T+++P I NT ++T Sbjct: 583 LIKHVLEEDAGFYLCKVSNDVGADI----SKSMYLTVKIPAMITSYPNTTRAEQGHMTEM 638 Query: 1218 --VEIPDETLDVTWYKKKSVIE-DTEKFTL----ISDVKKRTLIIRKCTEDDQCEYTCVL 1270 ++ + V W K+ +I D ++ + + D TL I +D ++C+ Sbjct: 639 SCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIA 698 Query: 1271 LDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFP--QPNDEWIVNSK 1326 +++ K ++ +V+ P E I+ D T+ + + F P + +N K Sbjct: 699 INSYGEDKGIIQLIVQDRPD----PPEVEIREVKDRTIALRWTMGFDGNSPITGYDINYK 754 Query: 1327 IIKKCKHTKPSIDSKSASLTIKK---VENTDAGIYKLRL--ENNCGHADVEMNVTILDKP 1381 K S +K S + + +E A Y +R+ +N G + +TI Sbjct: 755 --NKSASWASSQMTKDVSPQLNQATIIELHPASTYNIRMFAKNQIGESRPSNELTITTDE 812 Query: 1382 SPP-GKPNILE---IDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDT-----TEWISVK 1431 +PP G P ++ I S I + W P ++ N I Y V Y+E T I+V Sbjct: 813 APPDGAPQDVQLEAISSQGIKVTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTINVD 872 Query: 1432 NITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466 +T ++ NLK + Y R A N + SE Sbjct: 873 TTGDIETLTLDNLKKYTQYEVRVQAANRAGMGPTSE 908 Score = 116 bits (279), Expect = 7e-24 Identities = 168/776 (21%), Positives = 300/776 (38%), Gaps = 72/776 (9%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH---SITI 791 P +++ + V G V L + G+P P W ++N P+ +SD H S + Sbjct: 55 PVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPL-----ESDSRYHQSVSGLL 109 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 ++ + D G Y + NS G A+ + V++P + P +++ + Sbjct: 110 IEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSP-------RKVRGSVGSQVS 162 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 L VT + ITWYRN E I + I G N E ++ ++ D G Y+C A N Sbjct: 163 LFCSVTGSDEFDITWYRNAEKI--YQGINVRITGINNENLVMEGMAKSDGGAYQCFARN- 219 Query: 912 AGKSSHGARVTIDVEKVT---FVKHLQKSYETEEGKTVILECQTSHTVSTKW-YHNKKEI 967 GK S V + +E T +K E +++ + + + W + I Sbjct: 220 -GKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVI 278 Query: 968 SGMDHRE---IIQEGR-XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIR 1021 +HR I EG D GV +C + S + + P IR Sbjct: 279 KDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIR 338 Query: 1022 KLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 +++ + +D I I + W +D ++ + FE G ++ ++N+ Sbjct: 339 PMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNHRQRAFENNGTLKLSNVQNS- 397 Query: 1081 VHDEGEYSC-ILRD--ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--A 1135 DEGEY+C +L D + V V P +I +Q + G + + GD Sbjct: 398 --DEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQRVFIPCVVISGDLPM 455 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPS 1195 + W KDG I S + + L+I + G Y+C + ++ A+ E S Sbjct: 456 SITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTC-IARNEAAAV----EHS 510 Query: 1196 INFTLRL-PEFILVPANTDAYLTVEIP-------DETLDVTW-YKKKSVIEDTEKFTLIS 1246 I +++ P F + P + D + + + W + K + + + L S Sbjct: 511 IQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNS 570 Query: 1247 D-----VKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRI 1299 ++ +L+I+ E+D Y C + + +K V+ P I Y R Sbjct: 571 GSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRA 630 Query: 1300 KRGSDVTLLVDYQAFPQPNDEW-----IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++G + W I+N + + K D ++L I D Sbjct: 631 EQGHMTEMSCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVRED 690 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +G + N+ G + + + D+P PP + I E+ +I + W + GNS I Sbjct: 691 SGFFSCIAINSYGEDKGIIQLIVQDRPDPP-EVEIREVKDRTIALRWTMGFD-GNSPITG 748 Query: 1415 YVVEYQEIDTTEWIS---VKNITK--TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 Y + Y+ + W S K+++ Q +I L S+Y R +A N++ S S Sbjct: 749 YDINYKN-KSASWASSQMTKDVSPQLNQATIIELHPASTYNIRMFAKNQIGESRPS 803 Score = 92.3 bits (219), Expect = 1e-16 Identities = 130/595 (21%), Positives = 232/595 (38%), Gaps = 51/595 (8%) Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 SA + + EP + P+ ++ F+ V ++L + + +P P W R+N + Sbjct: 42 SARLLLSEPVDS---APVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPLESD 98 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 Q+ G IE + D+G Y C NS G + R+ + V + Sbjct: 99 SRYHQSVSGLLIEATRPS-----DAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVS--PR 151 Query: 937 SYETEEGKTVILECQT--SHTVSTKWYHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXD 993 G V L C S WY N ++I G++ R I D Sbjct: 152 KVRGSVGSQVSLFCSVTGSDEFDITWYRNAEKIYQGINVR--ITGINNENLVMEGMAKSD 209 Query: 994 VGVIKCIVKDQETSTM----LVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SETADVV 1048 G +C ++ + ST +V+++ P+ + + V + L + + V Sbjct: 210 GGAYQCFARNGKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVT 269 Query: 1049 WERDGE-IIKPKKNKYD--FEKRGHIRK-LYIRNTSVHDEGEYSCILRDE--SCTAEVTV 1102 W D + +IK ++ D GH+ L + +T V D G Y C + S + + + Sbjct: 270 WTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARI 329 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ 1161 P I ++N G + ++W+KD + + F NH Q + Sbjct: 330 NVRGPASIRPMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPF-NHRQRAFENNGT 388 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--TVE 1219 LK+ + D GEY+C V I S++ T+++P I + A + V Sbjct: 389 -LKLSNVQNSDEGEYTCYVLVDPEKQI----HRSVHVTVKVPPLIQHSDSQSASIGQRVF 443 Query: 1220 IP------DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 IP D + +TW+K I + T+ + +L I +E YTC+ + Sbjct: 444 IPCVVISGDLPMSITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNE 503 Query: 1274 KSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + + ++ +V+ PP ++ G VTL + P P W +SK + Sbjct: 504 AAAVEHSIQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVW-NHSKGAGVPQ 562 Query: 1333 HTKPSIDS-------KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 +++S ++ SL IK V DAG Y ++ N+ G AD+ ++ + K Sbjct: 563 FQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVG-ADISKSMYLTVK 616 Score = 89.8 bits (213), Expect = 7e-16 Identities = 132/588 (22%), Positives = 228/588 (38%), Gaps = 69/588 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V C V G ITW+R K Q + N LV+ + D G + C Sbjct: 158 GSQVSLFCSVTGSDEFDITWYRNAE--KIYQGINVRITGINNENLVMEGMAKSDGGAYQC 215 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A+N +T+ +V+ L D + I FS+K Sbjct: 216 FARNG----KMSTQDLVQVVLEDGTPK---------------------ILSAFSEK---- 246 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN--ISVAIESDMHMYCSVLKITNVK 701 V I L C + P P + W + ++ D N + I ++ H+ S L +++ + Sbjct: 247 VVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHV-LSYLNVSHTQ 305 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 G Y N G S + ++ P I P+K++ G + +++G Sbjct: 306 VSDGGVYRCTCNNSAGSVSYQARINVR-----GPASIRPMKNVTAIAGRDTYIHCRIIGY 360 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA-ENSEGIAETSAVI 820 P +I W K++ + + + + L + DEG YT + E S + Sbjct: 361 PYYSIKWYKDSNLLPFNHRQRAFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQIHRSVHV 420 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 TV+ P P + + Q ++ ++ I V ++ + SITW+++ I+ S +T Sbjct: 421 TVKVP------PLIQHSDSQSASIGQRVFIPCVV-ISGDLPMSITWHKDGRPINASLGVT 473 Query: 881 -QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 N D + L I+N+ SEI +G Y C+A N A H ++ + V V+ K + Sbjct: 474 IDNIDFTS-SLRISNL-SEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQ--PKDQD 529 Query: 940 TEEGKTVILECQT-SHTVST-KWYHNKK------EISGMDHREIIQEGRXXXXXXXXXXX 991 GK+V L C + + T W H+K + ++ +Q Sbjct: 530 GIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLLIKHVLE 589 Query: 992 XDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQD-FEVKEKDVAILEVEINSE-TAD 1046 D G C V + + S + + IP I + ++ + + + E Sbjct: 590 EDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRAEQGHMTEMSCTAHGEKPIK 649 Query: 1047 VVWERDGEIIKPKKNKY--DFEKRGH--IRKLYIRNTSVHDEGEYSCI 1090 V WE++ II P ++Y ++ G I L I +T D G +SCI Sbjct: 650 VRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCI 697 Score = 62.9 bits (146), Expect = 9e-08 Identities = 76/300 (25%), Positives = 122/300 (40%), Gaps = 36/300 (12%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDMHM 690 +PP +Q G + + C +++ P I W G I N S+ + D Sbjct: 424 VPPLIQHSD-SQSASIGQRVFIPCVVISGDLPMSITWHKDGRPI----NASLGVTIDNID 478 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + S L+I+N+ + G+YT +A N I L +K PP K G+ Sbjct: 479 FTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKV----PPHFEVQPKDQDGIYGK 534 Query: 751 SVILSAQVVGNPRPTITWCKNN-------KPVKALPTKSDGD--THSITILKPKKVKDEG 801 SV L+ GNP PTI W + +P+ AL + S + ++K +D G Sbjct: 535 SVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPI-ALNSGSRVQLLENGSLLIKHVLEEDAG 593 Query: 802 VYTLKAENSEGI-AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 Y K N G S +TV+ P I + T E+G + ++ Sbjct: 594 FYLCKVSNDVGADISKSMYLTVKIPA--------MITSYPNTTRAEQGHMTEMSCTAHGE 645 Query: 861 VP-SITWYRNNEIISPSET---ITQNFDGENI--ELVITNVDSEIDSGDYKCVASNSAGK 914 P + W + + II+P + +T G+ + L I + E DSG + C+A NS G+ Sbjct: 646 KPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVRE-DSGFFSCIAINSYGE 704 Score = 55.2 bits (127), Expect = 2e-05 Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 5/102 (4%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 SE AP+ ++ K G V+ C+ G+P P+ W R + P + Y+ Sbjct: 48 SEPVDSAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNS---PLESDSRYH-- 102 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 +V+ L+I P DAG++ C N+ G A L+V+ PL Sbjct: 103 QSVSGLLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPL 144 Score = 52.4 bits (120), Expect = 1e-04 Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 9/144 (6%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 ++TN+ + + + VVAV G + ++ ++ K P +++ ++ ++L Sbjct: 1078 RLTNLNQNWQYSIWVVAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLP 1137 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKAENSE 811 + VG+P PTI W K N A P DG + +++ K +D G Y A N+ Sbjct: 1138 CKAVGDPPPTIKWLKGNNGTPA-PVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNW 1196 Query: 812 GIAETSAVITVE----EPTEENAE 831 G E + V+ + +E+N+E Sbjct: 1197 GSDEIMLNLQVQGYILQYSEDNSE 1220 Score = 51.6 bits (118), Expect = 2e-04 Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 10/223 (4%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L++ ++K+ + V+A R G+ S I + K PP ++ S S Sbjct: 981 LELERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVPGPPAGVKAAASTSSVVFVSW 1040 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + ++ G R I +C N P ++ D + + + ++ + A + G Sbjct: 1041 LPPHKLNGIIRKYIVFCSNPYPTVISEFEAAPDVYFRRLTNLNQNWQYSIWVV-AVTAAG 1099 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYR-NN 870 TS +ITVE A+ P I F +T I L + +P P+I W + NN Sbjct: 1100 RGNTSEIITVEP----QAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLKGNN 1155 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +P + N VI V +E DSG Y+CVASN+ G Sbjct: 1156 GTPAPVSIDGRRSAHNNGSFVIRTVKAE-DSGYYRCVASNNWG 1197 Score = 39.9 bits (89), Expect = 0.75 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 4/82 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY----YDDDNVATLVIREVFPEDAG 579 G + C G ++ W +++ II P + D+ ++TL I ED+G Sbjct: 633 GHMTEMSCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSG 692 Query: 580 TFTCVAKNAAGFASSTTELIVE 601 F+C+A N+ G +LIV+ Sbjct: 693 FFSCIAINSYGEDKGIIQLIVQ 714 Score = 39.9 bits (89), Expect = 0.75 Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 7/167 (4%) Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945 W E + YI+++ + W ++ S + +EN+K F ++A+N Sbjct: 1196 WGSDEIMLNLQVQGYILQYSEDNSEEWGSY-SISPSERSYRLENLKCGTWYKFTLTAQNA 1254 Query: 1946 VGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIA 2004 VG S+ + + H P A N W+ GG P+ + + Sbjct: 1255 VGPG--RISEIIEAKTHGK--EPQFAKDHELFSSINSTRVELNLIGWNNGGCPIDSFTLE 1310 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 R V T W V K D T + DL E Y +++ N G +E Sbjct: 1311 YRPVDTTKWTMV-KRDSLTKSHILYDLQEATWYELQMRVGNSAGTAE 1356 Score = 37.9 bits (84), Expect = 3.0 Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 6/126 (4%) Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 R++ L T Y+F + A+N +G + T GK F ST + L Sbjct: 1235 RLENLKCGTWYKFTLTAQNAVGPGRISEIIEAKTHGKEPQFAKDHELFSSINSTRVELNL 1294 Query: 1885 -KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 W +NGG PI ++ +E++ V WT +V H + +++E ++ Sbjct: 1295 IGW----NNGGCPIDSFTLEYRPVDTTKWT-MVKRDSLTKSHILYDLQEATWYELQMRVG 1349 Query: 1944 NTVGVS 1949 N+ G + Sbjct: 1350 NSAGTA 1355 Score = 36.7 bits (81), Expect = 7.0 Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 6/155 (3%) Query: 1696 LELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 L++ Y ++ E ++ W + + +Y ++ L Y F + AQN VG S Sbjct: 1205 LQVQGYILQYSEDNSEEWGSYS-ISPSERSYRLENLKCGTWYKFTLTAQNAVGPGRI--S 1261 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWK 1814 E I KT P I++ V + NGG PI + +E + + KW Sbjct: 1262 EIIEAKTHGKEPQFAKDHELFSSINSTRVELNLI-GWNNGGCPIDSFTLEYRPVDTTKWT 1320 Query: 1815 XXXXXXXXXARI-QKLSINTTYQFRIYARNEIGTS 1848 + I L T Y+ ++ N GT+ Sbjct: 1321 MVKRDSLTKSHILYDLQEATWYELQMRVGNSAGTA 1355 >UniRef50_Q15746 Cluster: Myosin light chain kinase, smooth muscle; n=40; Theria|Rep: Myosin light chain kinase, smooth muscle - Homo sapiens (Human) Length = 1914 Score = 135 bits (327), Expect = 1e-29 Identities = 105/431 (24%), Positives = 182/431 (42%), Gaps = 52/431 (12%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 + S P F K + + + TV+F C+V G P+P++ WF + ++ + Y+D Sbjct: 408 QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 L + + D+GT++C A NA G S + L VE Sbjct: 468 GSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVER--------------------- 506 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 ++E + P+FS K V EG D +L+C + P P I WL G+ I + A Sbjct: 507 --LAVME-VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA 563 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL---------------PIVLKIK 728 +++H I + GTYT +A N G+ S +L + Sbjct: 564 GVAELH-------IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVA 616 Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD 785 + P ++ L + V G V ++ QV GNP P + W N ++ + G Sbjct: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 HS+ I + +D G YT +A NS G T AV+TV+EP + P FI++ + +T Sbjct: 677 QHSLWI-QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP--HDGTQPWFISKPRSVTAS 733 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 ++ + + +P P++ W R+ + + + E++ ++ +G Y+ Sbjct: 734 LGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYE 793 Query: 906 CVASNSAGKSS 916 + N G+ S Sbjct: 794 ILLKNRVGECS 804 Score = 127 bits (307), Expect = 3e-27 Identities = 96/366 (26%), Positives = 159/366 (43%), Gaps = 29/366 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESDMHMYC 692 P F KP++Q V E + C + IP+P++AW +G + E +I V ++ H C Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGE 750 + + GTY+ A N +G+ S L+++ + P LK V +G+ Sbjct: 474 ----LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 +L V G P P ITW N +P++ + + + I + +D G YT AEN+ Sbjct: 530 DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI-QDALPEDHGTYTCLAENA 588 Query: 811 EGIAETSAVITVEEPTEEN----------AEP--PLFINRFQEITVKEKGTIKLVARVTR 858 G SA +TV E ++P P+F+ ++ V + + + +V+ Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 NP P + W N I SE G L I V E D+G Y C A NSAG+ Sbjct: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPE-DTGTYTCEAWNSAGEVRTQ 707 Query: 919 ARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMD 971 A +T+ D + F+ +S G++V++ C + + W + K + Sbjct: 708 AVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766 Query: 972 HREIIQ 977 H E++Q Sbjct: 767 HFEVLQ 772 Score = 105 bits (251), Expect = 2e-20 Identities = 73/246 (29%), Positives = 105/246 (42%), Gaps = 12/246 (4%) Query: 487 KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 K + +D V P +E AP F+ R +G+T +FE +V GYP PQ+TW R Sbjct: 14 KTSLSVDPSRVDSMPLTE----APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 I F + +LVI V ED G +TC A N +G T EL VE + Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAK 129 Query: 607 HGSEMTVXXXXXXXXXXXXADILEGI----PPTFSKKPKAQYVDEGSDILLECRLVAIPE 662 + V + I PP F+ K V EG C++ P+ Sbjct: 130 QLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQ 189 Query: 663 PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLP 722 P + WL + P +SV+ ++ M VL+I V + G YT + VN G+AS+ Sbjct: 190 PQVTWLKGNVPLQPSARVSVSEKNGM----QVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245 Query: 723 IVLKIK 728 L I+ Sbjct: 246 AELSIQ 251 Score = 96.3 bits (229), Expect = 8e-18 Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 1/200 (0%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+I+ + + +++ G V L W+ K I++ +H K + LT Sbjct: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPE 1405 I G Y L +EN G ++N+T++DKP PP G P +I SSS+ + W Sbjct: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G S + Y +E + W + T ++Q+L + Y+FR A+N S+ S Sbjct: 1357 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416 Query: 1466 ETTEYYKVIKETKIQSPTVE 1485 + +E V ++ + VE Sbjct: 1417 QESELTTVGEKPEEPKDEVE 1436 Score = 94.7 bits (225), Expect = 2e-17 Identities = 69/241 (28%), Positives = 109/241 (45%), Gaps = 30/241 (12%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 P + + APIF++ L DGS V QV G P P++ W I+ S+DF + Sbjct: 614 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FE 672 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXX 620 +L I+EVFPED GT+TC A N+AG + L V+ P H Sbjct: 673 QRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---H------------- 716 Query: 621 XXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 +G P F KP++ G +L+ C + P P + WL G+ + D Sbjct: 717 ---------DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767 Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEKEPPQVIE 739 ++++ ++ VLK V+ + G Y ++ NR GE S + L ++ + + P+ E Sbjct: 768 FEVLQNE-DVFTLVLK--KVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGRE 824 Query: 740 P 740 P Sbjct: 825 P 825 Score = 92.3 bits (219), Expect = 1e-16 Identities = 43/117 (36%), Positives = 70/117 (59%), Gaps = 1/117 (0%) Query: 486 KKLNEKIDKLPVFEKPTSEEQS-MAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF 544 +KL + D F + +EE+ + P F + +R +GS +F+C++EGYP P++ WF Sbjct: 1784 EKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWF 1843 Query: 545 RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + I+ S+ FQ+ YD+D +L+I +V +D +TC A N+ G A+ T ELIVE Sbjct: 1844 KDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 Score = 81.4 bits (192), Expect = 2e-13 Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 3/176 (1%) Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 QK + G+ + + G P W K +++ + + E S + I ++ H Sbjct: 1247 QKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCG 1306 Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 YT+ N G+ +V L V DKP P G +I S+T+ W DGG + Y Sbjct: 1307 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366 Query: 1702 AIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESE 1756 +IE + N W ++A ++ +Q L + EY FRV A N G SE + ESE Sbjct: 1367 SIEIWDSANKTWKELATCRS--TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420 Score = 74.9 bits (176), Expect = 2e-11 Identities = 51/202 (25%), Positives = 87/202 (43%), Gaps = 18/202 (8%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXX 1539 +P+ LK+ +D L C G P P++TW +G+ ++ A++T E Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQD 572 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQ----------------KPVITISNEDIKQ- 1582 Y C+A N G+V S V + + KP I + + Sbjct: 573 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + +T + G PPPEVIW NGN+++ ++++ + + I+E+ + Sbjct: 633 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGT 692 Query: 1643 YTIEASNTAGTSSVEVTLKVYD 1664 YT EA N+AG + L V + Sbjct: 693 YTCEAWNSAGEVRTQAVLTVQE 714 Score = 68.9 bits (161), Expect = 1e-09 Identities = 85/402 (21%), Positives = 161/402 (40%), Gaps = 45/402 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P+F K Q EVKE E++ +V W +G ++ ++ + + L Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 1076 IRNTSVHDEGEYSCILRDE----SCT-----AEVTVVELPPEIITRLQNQKVNKGNKATF 1126 + D G YSC + SC+ + V+E+ P + L++ V +G Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 Query: 1127 EIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EV 1180 + + +G + R W +G IQ++ T + +L I D +D G Y+C + Sbjct: 534 QCSV-RGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENAL 589 Query: 1181 GNSKCTAILTVEE-----------------PSINFTLRLPEFILVPANTDAYLTVEIP-D 1222 G C+A +TV E P+ L+ + V + +TV++ + Sbjct: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK-V 1281 +V W + I+++E F + +L I++ +D YTC ++ + + V Sbjct: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709 Query: 1282 EVVEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTK 1335 V+ P P + R G V + P P W+ + K + K H + Sbjct: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769 Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + +L +KKV+ AG Y++ L+N G ++++ + Sbjct: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811 Score = 66.5 bits (155), Expect = 8e-09 Identities = 91/429 (21%), Positives = 168/429 (39%), Gaps = 47/429 (10%) Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 S+ + +A + + ++ P F ++ Q VKE T+K V+ P P + W+ Sbjct: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + E + ++ + DSG Y C ASN+ G+ S T+ VE++ Sbjct: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVS--CSWTLQVERLA 508 Query: 930 FVK------HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEI--------SGMDHR 973 ++ + K EG+ +L+C T + W N + I +G+ Sbjct: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAEL 568 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKC----IVKDQETST----MLVV---KETIPEFIRK 1022 I +G + C V ++++S +L V K T P F++ Sbjct: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628 Query: 1023 LQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081 L D +V + + V+++ +V+W +G I+ ++ + FE+RG L+I+ Sbjct: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED-FHFEQRGTQHSLWIQEVFP 687 Query: 1082 HDEGEYSCIL---RDESCTAEVTVVELP-----PEIITRLQNQKVNKGNKATFEIELTKG 1133 D G Y+C E T V V+ P P I++ ++ + G + G Sbjct: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA-G 746 Query: 1134 DAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCT 1186 D V W +DG + + + H ++ + L + AG+Y VG C Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 806 Query: 1187 AILTVEEPS 1195 L ++ S Sbjct: 807 VSLMLQNSS 815 Score = 66.5 bits (155), Expect = 8e-09 Identities = 35/106 (33%), Positives = 57/106 (53%), Gaps = 2/106 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 SE Q AP F +KL+ H +G + +CQV P I W +K ++ F + + Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQE 1149 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDH 607 ++ ++ I + PED G + CVAKN AG A + ++ V +AP S++ Sbjct: 1150 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195 Score = 65.7 bits (153), Expect = 1e-08 Identities = 47/213 (22%), Positives = 91/213 (42%), Gaps = 8/213 (3%) Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK 1523 +S +EY + +K +P + L ++ + +T G P P+V W +G +++ Sbjct: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664 Query: 1524 TAK-ATYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT---IS 1576 ++ +E R Y C A+N GEV T V+ +Q+ T Sbjct: 665 ESEDFHFEQRGTQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKEL 1635 ++ +G L++ I G P P V W ++G L D + + E + +K++ Sbjct: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + H+ +Y I N G S +V+L + + ++ Sbjct: 785 QPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817 Score = 61.7 bits (143), Expect = 2e-07 Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 33/222 (14%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHS 788 E P I P +++ +++G + +V G P P +TW +N +P+ + L T S Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 Query: 789 ITILKPKKVKDEGVYTLKAENS------------EG----------IAET-----SAVIT 821 + I + +D G YT +A N EG +++T SA Sbjct: 91 LVIHAVHE-EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAV 149 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 P+ PP F + + VKE + ++T P P +TW + N + PS ++ Sbjct: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + L I V+ + D G Y C+ N +GK+S A ++I Sbjct: 210 SEKNGMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSI 250 Score = 59.7 bits (138), Expect = 9e-07 Identities = 40/203 (19%), Positives = 85/203 (41%), Gaps = 12/203 (5%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXX-- 1536 P E ++ + N+ ++ C G+P+P+V W+ +G ++ + + YE+ Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKHKV--GDEWLV 1592 Y C A N G+V S + +++ V+ + S + + V G ++++ Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + G P P + W NG ++ + T + + + I++ YT A N G Sbjct: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIM 1675 S + V++K S + ++ Sbjct: 591 QVSCSAWVTVHEKKSSRKSEYLL 613 Score = 58.8 bits (136), Expect = 2e-06 Identities = 48/200 (24%), Positives = 87/200 (43%), Gaps = 12/200 (6%) Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 +KV + + + + E+C + ++ +N +G +A V T +D P Sbjct: 1284 MKVENSENGSKLTILAARQEHCG-CYTLLVENKLGSRQAQ-----VNLTVVDKPDPPAGT 1337 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARIQKLSIN 1832 I + S+ ++W+ S +GGS + Y +EI K WK +Q L + Sbjct: 1338 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPD 1397 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV-VSESTSRSVTLKWTEPES 1891 Y+FR+ A N GTS P + T+G+ P +P++ V VS+ + + + Sbjct: 1398 HEYKFRVRAINVYGTSEPSQESELTTVGE---KPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454 Query: 1892 NGGSPITN-YIIEFKTVKGK 1910 N +++ Y IE + GK Sbjct: 1455 NTEQKVSDFYDIEERLGSGK 1474 Score = 58.0 bits (134), Expect = 3e-06 Identities = 37/114 (32%), Positives = 53/114 (46%), Gaps = 7/114 (6%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP + S+ + SW +DGG+ + Y+I I D W E+ + Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC--RSTS 1388 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 FN++DL +H Y R+ A N G SEP + E V GE EEP ++ EV Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTV--GE---KPEEPKDEVEV 1437 Score = 56.0 bits (129), Expect = 1e-05 Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P + L+ + V +G+ ++L QV +P TI W N K +K + +G S++I Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTI 850 K +D G+Y A+N G AE S +TV++ P EN + P +R + ++ Sbjct: 1158 EKALP-EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216 Query: 851 KLVARVTRNPVP 862 + A V + P P Sbjct: 1217 ESDATVKKKPAP 1228 Score = 55.2 bits (127), Expect = 2e-05 Identities = 66/246 (26%), Positives = 102/246 (41%), Gaps = 43/246 (17%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI--------- 680 +G P F +K + +V EG +LL+C++ + P I W G+ + + I Sbjct: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153 Query: 681 SVAIES----DMHMY------------CSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 SV+IE D +Y CS + E T +R ++SLP V Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213 Query: 725 L--------KIKTGEKEPP------QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 L K K K PP Q+I+ + VR GESV L +V G T TW K Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273 Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 K ++ + ++ + +TIL ++ + G YTL EN G + +TV + + Sbjct: 1274 FRKQIQESEHMKVENSENGSKLTILAARQ-EHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332 Query: 828 ENAEPP 833 A P Sbjct: 1333 PPAGTP 1338 Score = 54.4 bits (125), Expect = 3e-05 Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP+ L ++V++G+ S ++ G P+P +TW K N P++ S + + + +L+ Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219 Query: 794 PKKVK--DEGVYTLKAENSEGIAETSAVITVE 823 V D GVYT N G A SA ++++ Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251 Score = 54.0 bits (124), Expect = 4e-05 Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 7/152 (4%) Query: 452 NQDWWYVQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNE-KIDKLPVFEKPTSEEQSMAP 510 ++D+ + Q+ T+ W+ + D YT E + + ++P Q P Sbjct: 666 SEDFHFEQRG-TQHSLWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ---P 721 Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLV 569 F+ K R G +V C + G P P + W R A+ K + F++ ++D V TLV Sbjct: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED-VFTLV 780 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +++V P AG + + KN G S L+++ Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812 Score = 54.0 bits (124), Expect = 4e-05 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 1/102 (0%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 E+ +E P F + Q++ V E + L +V+ +P +I W N + + ++ I + Sbjct: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1147 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 +G + I E D G YKCVA N AG++ +VT+D Sbjct: 1148 QEGSLCSVSIEKALPE-DRGLYKCVAKNDAGQAECSCQVTVD 1188 Score = 52.8 bits (121), Expect = 1e-04 Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 T P F +KLQD V E +L+ +++S+ A ++W +G+ +K K + G + Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEGSLCS 1154 Query: 1074 LYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129 + I D G Y C+ ++++ C+ +VTV + P T+ K + + + Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214 Query: 1130 LTKGDALVR 1138 T+ DA V+ Sbjct: 1215 GTESDATVK 1223 Score = 50.4 bits (115), Expect = 5e-04 Identities = 68/322 (21%), Positives = 122/322 (37%), Gaps = 29/322 (9%) Query: 1226 DVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LK 1280 +V W+ + + + E + D L + K D Y+C +A+ L+ Sbjct: 444 EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQ 503 Query: 1281 VE---VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 VE V+E P ++ + G D L + P P W++N + I ++ + + Sbjct: 504 VERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARST 560 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS- 1396 ++ A L I+ D G Y EN G VT+ +K S +L + S Sbjct: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620 Query: 1397 ---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 I + + + + V+ E I + N + Q S ++ + Sbjct: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES-EDFHFEQRGTQHS 679 Query: 1454 YAVNEVDISD-ASETTEYYKVIKETKIQSP-TVEKP-----------LKNITTEPNEDIE 1500 + EV D + T E + E + Q+ TV++P +++T + + Sbjct: 680 LWIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739 Query: 1501 LTCIFGGVPQPKVTWYRDGKKL 1522 ++C G P P V W RDGK L Sbjct: 740 ISCAIAGDPFPTVHWLRDGKAL 761 Score = 49.6 bits (113), Expect = 0.001 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P FSK + V EGS +C++ P+P++ W FK ++ + E+ I+ D Sbjct: 1807 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 1864 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 CS++ I++V + YT AVN GEA+ L ++T E+ Sbjct: 1865 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904 Score = 49.2 bits (112), Expect = 0.001 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 4/135 (2%) Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 +NLK+ S + N+V+ T + E++ +P ++ L+++ + + Sbjct: 1057 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX----XXXYKCIAFNDH 1556 L C P + W +GK LKT K ++ YKC+A ND Sbjct: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176 Query: 1557 GEVETSCVVGIQQKP 1571 G+ E SC V + P Sbjct: 1177 GQAECSCQVTVDDAP 1191 Score = 48.8 bits (111), Expect = 0.002 Identities = 26/94 (27%), Positives = 42/94 (44%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 E P FI + + +KE T K RV P P +TW+RN + I+ + Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 ++ + E D G Y C A+N +G +T++ Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124 Score = 47.2 bits (107), Expect = 0.005 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 L AE E + S E+ P F +++ V E + ++ P P + Sbjct: 1781 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1840 Query: 865 TWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W+++++ I S ++D + N L+I++V + D Y C A NS G+++ A + + Sbjct: 1841 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELIV 1899 Query: 924 D 924 + Sbjct: 1900 E 1900 Score = 45.6 bits (103), Expect = 0.015 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E PP+ T+L V +G F ++T + V W K +Q S + ++ Q Sbjct: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 L+I+ + DD G Y+C V N A ++ E Sbjct: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247 Score = 44.8 bits (101), Expect = 0.026 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 S+ S S+TL W +GGS + +Y IE K+W ++ T + ++++ Sbjct: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDH 1398 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 E FR+ A N G S P SQ L P P +E+ Sbjct: 1399 EYKFRVRAINVYGTSEP--SQESELTTVGEKPEEPKDEVEV 1437 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/88 (26%), Positives = 40/88 (45%) Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 ++ + G + L + P W +N K +K K S + S++I+K D Sbjct: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPS 1382 G+YK +N+ G A+ VT+ D P+ Sbjct: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA 1192 Score = 42.3 bits (95), Expect = 0.14 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164 P +++ +V +G+ A F+ ++ D V WFKD I+ S H Q+ D L Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192 I D DD +Y+C+ +G + CTA L VE Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 4/100 (4%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P+V W++NG + + + + + T + I + KYT EA+N +G Sbjct: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115 Query: 1655 SVEVTLKVYDKPSKPEG-PVIMREI-SRESVT-IEWKPPL 1691 V V L V +K G PV+ + + R S + +E +P + Sbjct: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSI 155 Score = 40.7 bits (91), Expect = 0.43 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTS 1654 IEG P PEV+W+K+ + + + I E + + I ++ +KYT +A N+ G + Sbjct: 1832 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1891 Query: 1655 SVEVTLKV 1662 + L V Sbjct: 1892 TCTAELIV 1899 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P + ++ + V +G + ++ G P P + W K+++ ++ D D + I Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + D+ YT KA NS G A +A + VE E E Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1908 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/103 (22%), Positives = 48/103 (46%), Gaps = 5/103 (4%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P +LQ+ V +G K + +++ A + W +G ++ + I L+ +G + I Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157 Query: 1166 YDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPE 1204 +D G Y C + G ++C+ +TV++ + + PE Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200 >UniRef50_UPI0000F201CC Cluster: PREDICTED: similar to Myomesin 2; n=1; Danio rerio|Rep: PREDICTED: similar to Myomesin 2 - Danio rerio Length = 1097 Score = 135 bits (326), Expect = 1e-29 Identities = 121/496 (24%), Positives = 204/496 (41%), Gaps = 48/496 (9%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +V WY++G + + T +++ + +K + + H YT+ GT VE + V Sbjct: 213 DVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGT--VEHSAYV 270 Query: 1663 YDKPSK------PEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 Y K P P+ ++ +++R+ V + W PP DG + Y IE+ + +W Sbjct: 271 YVKDGSAVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWE 330 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQN------------PVGFSEALE-SEPIVIK 1761 + DV + V Y + L EN Y FRV A N P+ S+ LE S +V+K Sbjct: 331 RCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVK 390 Query: 1762 TA---------------LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 + VP D +V + W + G P+ Y VE Sbjct: 391 VERGRQIVITKDQLEGQIRVPFPPTEVQVCELSDTYAV-LRWTEPDPRGREPL-KYFVER 448 Query: 1807 KQEG-KKWKXXXXXXXXXA-RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 G + W + R +Y +R+ + N+ G S P I++G+ Sbjct: 449 SISGTESWHLASMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQP 508 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P+ P + T+ SV L+W EP G I Y + W I + Sbjct: 509 QGVPAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITT 566 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGSN 1981 ++ +K + +FR+ + G S+ +E S +R++ VPS P+A + + Sbjct: 567 TRFTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRVKAALNVPSCPSAISVLNCSRAE 626 Query: 1982 IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 +V+ W P GG P+ GY + R ++++W EV V + + L E H R+ Sbjct: 627 MVI-GWRAPVNHGGDPVRGYYLDQRQKSESIWREVNVRPVKERVYKLTGLQEGHFCQFRV 685 Query: 2042 YARNEIGLSEPLESDE 2057 +A N IG+ +P E E Sbjct: 686 FAANIIGVGKPSEPSE 701 Score = 83.4 bits (197), Expect = 6e-14 Identities = 73/306 (23%), Positives = 120/306 (39%), Gaps = 11/306 (3%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P V + E+S + W P D G E KY +E+ W +A +D V + Sbjct: 413 PPTEVQVCELSDTYAVLRWTEP-DPRGREPLKYFVERSISGTESW-HLASMDMTVLSTRF 470 Query: 1729 QKLNENC--EYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 ++ Y +RV + N G SE +L S+PI + VP+ N SV Sbjct: 471 SAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQPQGVPAPPSGVLPMRDT-NSSVL 529 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTYQFRIYAR 1842 + W G I+ Y + + G +WK R + L N Y FR+ + Sbjct: 530 LQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRFTVDGLKSNKQYVFRVKSV 587 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 G S+ I + L PS P V + + + W P ++GG P+ Y + Sbjct: 588 GVSGNSIYSEESPVIRVKAALNVPSCPSAISVLNCSRAEMVIGWRAPVNHGGDPVRGYYL 647 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + + W ++ + + ++E FR+ A N +GV P+E + L + Sbjct: 648 DQRQKSESIWREVNVRPVKERVYKLTGLQEGHFCQFRVFAANIIGVGKPSEPSELLLCEP 707 Query: 1963 ATVPSP 1968 T+P P Sbjct: 708 WTMPEP 713 Score = 74.1 bits (174), Expect = 4e-11 Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 20/227 (8%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVAT 567 AP F LRP G V+ C V+G+P P ITWF+ A ++P + + Sbjct: 64 APDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLHI 123 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX-XXXXXXXA 626 L IR EDAG + +A+++ G A+S+ LIV S G+E + A Sbjct: 124 LEIRRCSAEDAGEYKVIARSSLGEAASSATLIVN---SHEGAEAKLQRSFTPIPVPEPDA 180 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVA--IP-EPDIAWLFKGEEIVPDENISVA 683 + P TF V EG +++L+C +P + D+ W G + P S Sbjct: 181 QLASTFPSTF--------VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRP----SSR 228 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG 730 +E + + L + +V K EG YTV +G + +K G Sbjct: 229 VELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGTVEHSAYVYVKDG 275 Score = 63.3 bits (147), Expect = 7e-08 Identities = 27/83 (32%), Positives = 44/83 (53%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T ++G P PE+ W KN ++ + +YNI + K+S + I + S Y+I N Sbjct: 1013 LTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSMEDSGNYSIFVRNKH 1072 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVI 1674 G+ +V VT+ VY KP G + Sbjct: 1073 GSQTVLVTVSVYKHGEKPRGDAV 1095 Score = 57.6 bits (133), Expect = 4e-06 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDE---WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 +K G ++ L + P + W + ++ + +SASLT+K V Sbjct: 191 VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHE 250 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSIN-----ICWDEPEN 1406 G+Y +RL G + V + D + PG P L++ S +N + W P Sbjct: 251 GLYTVRLRTWDGTVEHSAYVYVKDGSAVVVGAPGSP--LQVKCSDVNRDYVFLSWIPPSA 308 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 G + + Y +E +I +W ++ + Q + LK N+ Y+FR AVN+ + Sbjct: 309 DGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRP 368 Query: 1465 SETTE 1469 S+ +E Sbjct: 369 SKPSE 373 Score = 53.6 bits (123), Expect = 6e-05 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%) Query: 1963 ATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 A V P +PL+++ V + V SW P DG A + GY I D+ W V Sbjct: 277 AVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVI 336 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ + L EN Y R+ A N+ G+ P + EP Sbjct: 337 QKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEP 374 Score = 48.0 bits (109), Expect = 0.003 Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 25/213 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P FS + V G D+ L C + P+P I W + P + I S ++ Sbjct: 65 PDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLH-- 122 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE---------------KEPP-QV 737 +L+I G Y V+A + GEA+ L + + E EP Q+ Sbjct: 123 ILEIRRCSAEDAGEYKVIARSSLGEAASSATLIVNSHEGAEAKLQRSFTPIPVPEPDAQL 182 Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRP---TITWCKNN---KPVKALPTKSDGDTHSITI 791 S V++G++++L P +TW ++ +P + ++ + S+T+ Sbjct: 183 ASTFPSTFVKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTV 242 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 K + EG+YT++ +G E SA + V++ Sbjct: 243 KHVHK-EHEGLYTVRLRTWDGTVEHSAYVYVKD 274 Score = 48.0 bits (109), Expect = 0.003 Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 25/211 (11%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSD-GDTHSITIL 792 P PL+ V G V LS V G P P+ITW K++ P++ LP + IL Sbjct: 65 PDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRFGLHIL 124 Query: 793 KPKK--VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL---------------F 835 + ++ +D G Y + A +S G A +SA + V + E AE L Sbjct: 125 EIRRCSAEDAGEYKVIARSSLGEAASSATLIVN--SHEGAEAKLQRSFTPIPVPEPDAQL 182 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVP---SITWYRNNEIISPSETITQNFDGENIELVI 892 + F VKE + L T +P +TWYR+ + PS + + L + Sbjct: 183 ASTFPSTFVKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTV 242 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +V E G Y G H A V + Sbjct: 243 KHVHKE-HEGLYTVRLRTWDGTVEHSAYVYV 272 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 P+PP + +SS+ + W EP T I+ Y + E + +W ++ N IT T+ Sbjct: 512 PAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRF 569 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 ++ LK+N Y FR +V S SE + +V Sbjct: 570 TVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRV 604 Score = 40.7 bits (91), Expect = 0.43 Identities = 14/53 (26%), Positives = 30/53 (56%) Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 + ++ K +++ +++P PL+ T D++L+C G P P +TW++D Sbjct: 49 KAAQHLKHVQDLSLKAPDFSVPLRPHTVWCGMDVKLSCSVQGFPDPSITWFKD 101 Score = 39.1 bits (87), Expect = 1.3 Identities = 21/94 (22%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435 L+ PS P ++L + + I W P N G + Y ++ ++ + W ++V+ + + Sbjct: 608 LNVPSCPSAISVLNCSRAEMVIGWRAPVNHGGDPVRGYYLDQRQKSESIWREVNVRPVKE 667 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + L+ +FR +A N + + SE +E Sbjct: 668 RVYKLTGLQEGHFCQFRVFAANIIGVGKPSEPSE 701 Score = 38.7 bits (86), Expect = 1.7 Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 8/93 (8%) Query: 850 IKLVARVTRNPVPSITWYRNNEIISP----SETITQNFDGENIELVITNVDSEIDSGDYK 905 +KL V P PSITW++++ + P + I+ F G +I L I +E D+G+YK Sbjct: 82 VKLSCSVQGFPDPSITWFKDDAPMQPPLPWNYRISSRF-GLHI-LEIRRCSAE-DAGEYK 138 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 +A +S G+++ A + ++ + K LQ+S+ Sbjct: 139 VIARSSLGEAASSATLIVNSHEGAEAK-LQRSF 170 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNIT--KTQ 1437 P PP + + E+ + + W EP+ G + Y+ VE T W ++ ++T T+ Sbjct: 411 PFPPTEVQVCELSDTYAVLRWTEPDPRGREPLKYF-VERSISGTESWHLASMDMTVLSTR 469 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 S + + SY +R +VN+ IS+ S Sbjct: 470 FSAFDQQKGKSYSYRVRSVNKYGISEPS 497 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/107 (21%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Query: 726 KIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TK 781 +++ EK +V + L ++ + + +S+ L+ V G+P P + W KN++ + + K Sbjct: 984 QVEFAEKNRARVTKGLPDVVAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIK 1043 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 ++ + ++TI ++D G Y++ N G ++V + E+ Sbjct: 1044 NENKSSTLTI-NHVSMEDSGNYSIFVRNKHGSQTVLVTVSVYKHGEK 1089 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + + E ++ L V +P P + W +N+ IS + + ++ L I +V E DS Sbjct: 1003 VAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSME-DS 1061 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEK 927 G+Y N G S VT+ V K Sbjct: 1062 GNYSIFVRNKHG--SQTVLVTVSVYK 1085 >UniRef50_UPI0000E46295 Cluster: PREDICTED: similar to Down syndrome cell adhesion molecule, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Down syndrome cell adhesion molecule, partial - Strongylocentrotus purpuratus Length = 2430 Score = 135 bits (326), Expect = 1e-29 Identities = 180/820 (21%), Positives = 308/820 (37%), Gaps = 75/820 (9%) Query: 695 LKITNVKKFQEGTYTVVAVNR---EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L I +V+ G Y NR + S P VL + P++I+ +R GE+ Sbjct: 624 LHIRDVRDRDAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGET 683 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 V L G P PT W K+ PV P S +L ++++ G Y +A N Sbjct: 684 VELPCVASGYPLPTYQWTKDGVPVT--PGDSRSLRGGNLLLSNVQLENAGRYDCEAVNDL 741 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G T+ + V + P Q+ +V V+ P+ +TWY+N + Sbjct: 742 GAVSTTRNVIVRDSIAVYFYP-------QKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQ 794 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + + +T EN +V+ + + D G Y+CVASNS ++++ K + Sbjct: 795 PLDGDDRVTVY---ENGTMVVGGMRRD-DRGMYQCVASNSWQTQEATMQLSLGAAKPIML 850 Query: 932 KHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISG---MDHREIIQEGRXXXXXX 986 H + G + L C + T W + I ++I E Sbjct: 851 AHFTNQ-TLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYL 909 Query: 987 XXXX--XXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQD-FEVKEKDVAILEVEIN 1041 D G+ +C + + + + +R L D + DV+I + Sbjct: 910 NISRLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSIHCHVVG 969 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR----DESCT 1097 + W + G P +++ G + + TS D GEY+C+ D S + Sbjct: 970 FPITSITWYK-GLTTLPSSMRHNVFPNGTL--VIADVTSYGDGGEYTCVASNARGDRSAS 1026 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLT 1155 +V++PP +I ++ + +G + +T+GD + RW KDG I I+ Sbjct: 1027 DMDLIVKVPP-VIQPIEPLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHGVGIEFV 1085 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKC----TAILTVEEPSINFTLRLPEFILVPAN 1211 L I D G Y+CE N T LT++ P P F++ P N Sbjct: 1086 NGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVP--------PRFVVEPHN 1137 Query: 1212 TDAYL--TVEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVK-----KRTLIIRKCT 1259 T L TV I DV W K I T L D + +L+IR+ Sbjct: 1138 TAVVLNHTVVIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREAR 1197 Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYERE-YRIKRGSDVTLLVDYQAFPQPN 1318 +D Y C + ++ + F P + +++ ++ +TL Sbjct: 1198 VEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELTESITLECIATGHQPLE 1257 Query: 1319 DEWIVNSKIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 W N + + I DS +S+TI D Y +N G + Sbjct: 1258 IMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQNLHGADEHV 1317 Query: 1373 MNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-- 1430 + + + +KP PP +++ S + + W +P GNS + + +EY+ + Sbjct: 1318 IQLWVQEKPEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQTGLPQ 1376 Query: 1431 ----KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 ++ Q SI++L +Y R +A N + ISD S+ Sbjct: 1377 EHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSK 1416 Score = 84.2 bits (199), Expect = 4e-14 Identities = 202/996 (20%), Positives = 370/996 (37%), Gaps = 102/996 (10%) Query: 1073 KLYIRNTSVHDEGEYSCILRDE-------SCTAEVTVVE---LPPEIITRLQNQKVNKGN 1122 +L+IR+ D G+Y C +R+ S A + V E PE+I + + G Sbjct: 623 ELHIRDVRDRDAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGE 682 Query: 1123 KATFEIE-LTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 T E+ + G L +W KDG + + L + L + + L++AG Y CE Sbjct: 683 --TVELPCVASGYPLPTYQWTKDGVPVTPGDSRSL----RGGNLLLSNVQLENAGRYDCE 736 Query: 1180 VGNSKCTAILTVEEPSINFTLRL---PEFILVPANTDAYLTVEIPDETLD-VTWYKKKSV 1235 N A+ T + ++ + P+ V A + ++ VTWYK Sbjct: 737 AVND-LGAVSTTRNVIVRDSIAVYFYPQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQP 795 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDY 1293 ++ ++ T+ + T+++ DD+ Y CV ++ T + +++ + P ++ + Sbjct: 796 LDGDDRVTVYEN---GTMVVGGMRRDDRGMYQCVASNSWQTQEATMQLSLGAAKPIMLAH 852 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSI---DSKSAS-LTIK 1348 ++ G ++ L P P+ W+ + I ++T + DS S L I Sbjct: 853 FTNQTLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNIS 912 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG 1408 ++ + D G+Y+ + G E + ++ +P P+++ ID + ++I G Sbjct: 913 RLVSEDGGLYRCEATSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSI---HCHVVG 969 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTN--SSYRFRAYAVNEVDISDASE 1466 I + Y+ + T N+ T + T+ + A N AS+ Sbjct: 970 FP--ITSITWYKGLTTLPSSMRHNVFPNGTLVIADVTSYGDGGEYTCVASNARGDRSASD 1027 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525 KV P V +P++ +T + +L CI P W +DG+ + Sbjct: 1028 MDLIVKV--------PPVIQPIEPLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHG 1079 Query: 1526 KA-TYENRXXXXX---XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP--VITISNED 1579 + N Y C A N V + + IQ P V+ N Sbjct: 1080 VGIEFVNGTFSSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTA 1139 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYK--------NGNKLENDKEYNITTKEKTSVIR 1631 + H V ++ + G P P+V W K N L +D + + +E S++ Sbjct: 1140 VVLNHTV----VIACMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEM--QENGSLV- 1192 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE----W 1687 I+E + + Y SN+ G S TL V+ + + + ES+T+E Sbjct: 1193 IREARVEDAGYYLCHISNSVGMESKTATLTVFVPATFEQQQQNVTVELTESITLECIATG 1252 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 PL+ + +K + + R+ V D D + + I + + +AQN Sbjct: 1253 HQPLE---IMWSKNDVPFNRLTTARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQN 1309 Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G E + + ++ + P+ + V ++W PS +G SP+ + +E Sbjct: 1310 LHGADEHVIQ--LWVQEKPEPPTDLHVVNKT----SRGVLLSWQPS-FDGNSPVTGFTLE 1362 Query: 1806 IKQEGKKWKXXXXXXXXXA-------RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 K W+ A I+ L TY RI+A N IG S P T Sbjct: 1363 YKNASDAWQTGLPQEHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDT 1422 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII-----EFKTVKGKSWT 1913 + P+ V ++ ++K P I + K + + Sbjct: 1423 EEEDAWQTGLPQEHVPADLIGYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDTEE 1482 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPL 1973 ++ + + N+K+ ++ A N V V + Q V + VPS + Sbjct: 1483 EVPVETNYIESRTLTNLKKFTRYTIQLRAYNRVNVGPWSPQQFVTTLE--DVPSEAPHDV 1540 Query: 1974 EIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV 2008 R VGS +M W P+ L GY + R + Sbjct: 1541 SARSVGSTSIMVFWNAPDQVSLNGILQGYRVYYRPI 1576 Score = 83.0 bits (196), Expect = 8e-14 Identities = 122/577 (21%), Positives = 213/577 (36%), Gaps = 63/577 (10%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ + VD G+ C + P + W + + D+ ++V M + Sbjct: 762 PQKRSVDVGAFATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYENGTM-------VVGG 814 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 +++ G Y VA N + L + + P ++ + ++ G ++ LS V Sbjct: 815 MRRDDRGMYQCVASNSWQTQEATMQLSLGAAK---PIMLAHFTNQTLQPGPNLQLSCTVA 871 Query: 760 GNPRPTITWCKNNKPVKALP-------TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 GNP P +TW ++ P+ P D D S + +D G+Y +A Sbjct: 872 GNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVISYLNISRLVSEDGGLYRCEA----- 926 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 TS + V+ N + ++ + + + V P+ SITWY+ Sbjct: 927 ---TSELGAVQHEDRINVIGRPLVRPLPDVIAIDGTDVSIHCHVVGFPITSITWYKGLTT 983 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + PS F N LVI +V S D G+Y CVASN+ G S + + + V+ ++ Sbjct: 984 L-PSSMRHNVF--PNGTLVIADVTSYGDGGEYTCVASNARGDRS-ASDMDLIVKVPPVIQ 1039 Query: 933 HLQKSYETEEGKTVILEC---QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 ++ +G+ L C + + + +W + + I E + Sbjct: 1040 PIE-PLTLRQGQRTQLMCIVTRGDYPIHFRWLKDGETIPHGVGIEFVNGTFSSSLLIADA 1098 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TA 1045 G C + + TI P F+ + + V ++ N + Sbjct: 1099 STVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIACMANGKPNP 1158 Query: 1046 DVVWER-DGEIIK------PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----E 1094 DV W++ G I P +++ ++ G L IR V D G Y C + + E Sbjct: 1159 DVQWKKAPGPITTTNFRDLPDDPRFEMQENG---SLVIREARVEDAGYYLCHISNSVGME 1215 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSN--- 1150 S TA +TV +P + QN V T E T L + W K +++ F+ Sbjct: 1216 SKTATLTVF-VPATFEQQQQNVTVELTESITLECIATGHQPLEIMWSK--NDVPFNRLTT 1272 Query: 1151 ---HIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGN 1182 I+ DG + I+ DD Y C N Sbjct: 1273 ARYDIETVTDGDSVLSSMTIFSAVRDDTATYICLAQN 1309 Score = 68.1 bits (159), Expect = 2e-09 Identities = 50/190 (26%), Positives = 91/190 (47%), Gaps = 8/190 (4%) Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXA-RIQKLSINTTYQFR 1838 N ++ + W S NGGS I+ +++ ++ ++ W+ + R L T Y+F Sbjct: 1849 NNAIKVNW-RSTGNGGSSIVAFQLLYQRTHEQTWERFDVNASLRSFRATDLLCGTGYRFY 1907 Query: 1839 IYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 I ARN++G P T G+ PPS + +V + + S+TL +S GG PI Sbjct: 1908 ITARNKLGVGKPSDILSVSTQGEIPIPPSTDK--IVPFTNASSITLVLASWQS-GGCPIE 1964 Query: 1899 NYIIEFKTVKGKSWTKIV-TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL-PTESQS 1956 +Y I+++ + W I + G+ ++ +++++ FR++A NT G S+ P + Sbjct: 1965 SYSIQYQVLGVDDWENIANNLPGNTRDYTVDDLRPLTWYQFRVTAVNTAGPSVYPFRVST 2024 Query: 1957 VRLEKHATVP 1966 V T P Sbjct: 2025 VAFSGSGTAP 2034 Score = 66.9 bits (156), Expect = 6e-09 Identities = 85/394 (21%), Positives = 151/394 (38%), Gaps = 34/394 (8%) Query: 1669 PEGPVIMRE--ISRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDRDVET 1725 PE P ++ S S+ + W PPL G+ +T Y + ++ N + ++D Sbjct: 1645 PEAPADIKAHAASPTSIMVSWLPPLYLNGI-ITHYHLNIQYREGENEVRQEKELDPTTYY 1703 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXID-NES 1783 Y ++ L + EY F V A G E S I + + VP+ Sbjct: 1704 YLVEDLQTDYEYDFWVKASTIAGQGE---SSRIATEIPMSRVPARIMSFSTTLMTPWKRG 1760 Query: 1784 VYITWFPSEKNGGSPIIDY---KVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 V + P G P++ K + K IQ + + Sbjct: 1761 VTLDCLPV----GDPVLTVEWKKNRLPNVLKPDGRIDILENGSLVIQSVQSTDAGNYTCR 1816 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A NE G+S D IT+ + P P + +++ ++ + W NGGS I + Sbjct: 1817 AINEYGSS------DSITVRVQVLAPPNPPQLTIGSTSNNAIKVNW-RSTGNGGSSIVAF 1869 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 + ++ ++W + V S+ ++ F I+A N +GV P++ SV + Sbjct: 1870 QLLYQRTHEQTWERF-DVNASLRSFRATDLLCGTGYRFYITARNKLGVGKPSDILSVSTQ 1928 Query: 1961 KHATVPSPPTAPLEIRMVGSN---IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV- 2016 +P PP+ + ++ +V+ SW + GG P+ Y+I + + W + Sbjct: 1929 --GEIPIPPSTDKIVPFTNASSITLVLASWQS----GGCPIESYSIQYQVLGVDDWENIA 1982 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 + NT + + DL Y R+ A N G S Sbjct: 1983 NNLPGNTRDYTVDDLRPLTWYQFRVTAVNTAGPS 2016 Score = 50.8 bits (116), Expect = 4e-04 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 6/83 (7%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP-EDAGTF 581 DG+ V C V G+P ITW++ + S ++ + TLVI +V D G + Sbjct: 957 DGTDVSIHCHVVGFPITSITWYKGLTTLPSSMRHNVFPN----GTLVIADVTSYGDGGEY 1012 Query: 582 TCVAKNAAGFAS-STTELIVEAP 603 TCVA NA G S S +LIV+ P Sbjct: 1013 TCVASNARGDRSASDMDLIVKVP 1035 Score = 47.6 bits (108), Expect = 0.004 Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 8/92 (8%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM-----EVGKVD 2020 P PPT L + S V+ SW P +DG +P+ G+ + ++ + W E D Sbjct: 1326 PEPPT-DLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDA-WQTGLPQEHVPAD 1382 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + +++I+ L +TY +RI+A N IG+S+P Sbjct: 1383 LIGYQYSIKHLHPAYTYHVRIFAFNAIGISDP 1414 Score = 47.2 bits (107), Expect = 0.005 Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 14/215 (6%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI----VTVGGS 1921 P P + V TSR V L W +P +G SP+T + +E+K T + V Sbjct: 1326 PEPPTDLHVVNKTSRGVLLSW-QPSFDGNSPVTGFTLEYKNASDAWQTGLPQEHVPADLI 1384 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH-ATVPSPPTAPLEIRMVGS 1980 +++ I+++ RI A N +G+S P++ E+ A P + ++G Sbjct: 1385 GYQYSIKHLHPAYTYHVRIFAFNAIGISDPSKEILFDTEEEDAWQTGLPQEHVPADLIGY 1444 Query: 1981 NIVMTSWGTPEWDGGAPLLGYN-IAIRDVTKTMWMEV-GKVDVNTLKFNIRDLSE----- 2033 + P + + +N I I D +K + + +V V T R L+ Sbjct: 1445 QYSIKHL-HPAYTYHVRIFAFNAIGISDPSKEILFDTEEEVPVETNYIESRTLTNLKKFT 1503 Query: 2034 NHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSH 2068 +T +R Y R +G P + + +P E H Sbjct: 1504 RYTIQLRAYNRVNVGPWSPQQFVTTLEDVPSEAPH 1538 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 6/93 (6%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-----ATLVIREVFPEDAGT 580 TV C G P P + W + I + +F+ DD +LVIRE EDAG Sbjct: 1145 TVVIACMANGKPNPDVQWKKAPGPITTT-NFRDLPDDPRFEMQENGSLVIREARVEDAGY 1203 Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 + C N+ G S T L V P + + V Sbjct: 1204 YLCHISNSVGMESKTATLTVFVPATFEQQQQNV 1236 Score = 43.6 bits (98), Expect = 0.061 Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 5/125 (4%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D Y ++ +L P +E + AP ++ G TV+ C G Sbjct: 633 DAGQYRCTVRNRLTNNNKVSPPAVLHVAEPVNTAPELIQSKADFTLRGGETVELPCVASG 692 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 YP P W + + P + L++ V E+AG + C A N G S+T Sbjct: 693 YPLPTYQWTKDGVPVTPGDSRSL-----RGGNLLLSNVQLENAGRYDCEAVNDLGAVSTT 747 Query: 596 TELIV 600 +IV Sbjct: 748 RNVIV 752 Score = 43.2 bits (97), Expect = 0.081 Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ F C V GYP Q+TW++ + +Y + T+V+ + +D G + C Sbjct: 770 GAFATFNCSVSGYPIEQVTWYKNAQPLDGDDRVTVYEN----GTMVVGGMRRDDRGMYQC 825 Query: 584 VAKNAAGFASSTTELIVEA 602 VA N+ +T +L + A Sbjct: 826 VASNSWQTQEATMQLSLGA 844 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 4/85 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII--KPSQDFQ--MYYDDDNV 565 PI + + G +Q C V G P P +TW R I P F + D D + Sbjct: 847 PIMLAHFTNQTLQPGPNLQLSCTVAGNPTPDVTWLRDGLPIPTDPRYTFNDVINEDSDVI 906 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAG 590 + L I + ED G + C A + G Sbjct: 907 SYLNISRLVSEDGGLYRCEATSELG 931 Score = 39.1 bits (87), Expect = 1.3 Identities = 51/243 (20%), Positives = 81/243 (33%), Gaps = 15/243 (6%) Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654 ++ L++ + H T + +PP F +P V +++ Sbjct: 1090 SSSLLIADASTVHDGRYTCEASNLAAAVNYTTALTIQVPPRFVVEPHNTAVVLNHTVVIA 1149 Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY-CSVLKITNVKKFQEGTYTVVAV 713 C P PD+ W I + + M L I + G Y Sbjct: 1150 CMANGKPNPDVQWKKAPGPITTTNFRDLPDDPRFEMQENGSLVIREARVEDAGYYLCHIS 1209 Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 N G S L + P + +++ V ES+ L G+ I W KN+ Sbjct: 1210 NSVGMESKTATLTVFV----PATFEQQQQNVTVELTESITLECIATGHQPLEIMWSKNDV 1265 Query: 774 PVKALPTK-------SDGDT--HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 P L T +DGD+ S+TI + D Y A+N G E + V+E Sbjct: 1266 PFNRLTTARYDIETVTDGDSVLSSMTIFSAVR-DDTATYICLAQNLHGADEHVIQLWVQE 1324 Query: 825 PTE 827 E Sbjct: 1325 KPE 1327 >UniRef50_A7DN46 Cluster: Fibronectin, type III domain protein precursor; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Fibronectin, type III domain protein precursor - Candidatus Nitrosopumilus maritimus SCM1 Length = 9645 Score = 134 bits (324), Expect = 3e-29 Identities = 118/439 (26%), Positives = 182/439 (41%), Gaps = 29/439 (6%) Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSS-VEVTLKVYDKPSKPEGPVIMREISRESV 1683 + ++ + + +L + + A N G S + K P P+ + + + + V Sbjct: 6600 DTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDPATASAKPATTPGAPDA--LQLDFANQLV 6657 Query: 1684 TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD--VDRDVETYCIQKLNENCEYMFRV 1741 ++EW P DDGG E+ Y +E + D + WI D + + L +Y FR+ Sbjct: 6658 SLEWAVPTDDGGDEIDDYIVE-YSLDTSEWIVFPDNVTPANSTAVTVTDLINGFQYFFRI 6716 Query: 1742 IAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID 1801 N G E E T P DN SV++TW E GG+P+ Sbjct: 6717 SGVNIAGIGEPSEFRATTPATLPSAPRDLEATR-----DNTSVHLTWNVPEDLGGAPLSA 6771 Query: 1802 YKVEIKQEGK----KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 Y VE G+ K+ + L+ YQFRI A+N T SD Sbjct: 6772 YMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQYQFRITAKNTAITDFGPASD--- 6828 Query: 1858 TIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 T+ T T P+ PR+ VV +++ TL W PESNGG IT+Y IE + + G+ W Sbjct: 6829 TVSATPATTPTAPRDLVVIAGNNQA-TLSWNVPESNGGDSITDYKIEIR-IAGQDWDVYD 6886 Query: 1917 T-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 V + I N+ FR++A N+V P + V K AT+P+PP + I Sbjct: 6887 DGVSTTTQGIVIPNLTNGVTYEFRVTAINSVN---PGPASDVVPGKPATIPTPPKKLVVI 6943 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAI-RDVT-KTMWMEVGKVDVNTLKFNIRDLSE 2033 G + +W P +GG+ + Y + D T V D+ L I L Sbjct: 6944 --PGDTKLDVTWTKPTNNGGSAITSYLVQYSTDGTFDASTPSVTVTDLTNLMVTISGLEN 7001 Query: 2034 NHTYMIRIYARNEIGLSEP 2052 + +++ A N +G S P Sbjct: 7002 DVPIHVQVTAINGVGSSGP 7020 Score = 131 bits (316), Expect = 2e-28 Identities = 178/758 (23%), Positives = 292/758 (38%), Gaps = 66/758 (8%) Query: 1346 TIKKVENTDAGI-YKLRL--ENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICW 1401 T+ +E+ + G+ Y+ R+ EN G D +T P + + + +++ W Sbjct: 4791 TVVDIEDLENGVEYQFRISAENEVGFGDPSAPITATPVDGPSQVTGLSGQRGNGEVSLSW 4850 Query: 1402 DEPENTGNSTIIYYVVEYQE--IDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNE 1458 EP + G TI YV+EY + T +V + T I NL+ +Y FR YA N+ Sbjct: 4851 SEPFD-GGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLENGVTYEFRVYAQND 4909 Query: 1459 VDISDASETTEYYKVIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 +D S T T + PT ++ + D + I + + K+ Sbjct: 4910 IDDGPVSTTISVTPATVPTPPTNLIPTFGSTQVSLGWTASSDDGGSDIDDYIVEFKLKSE 4969 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 D + + ++ A ND G + S V + P + Sbjct: 4970 SDWQVFNDGVSDVPG---ATVTGLTNGQIYEFRVKAHNDVGNSDPSEVK--EATPAAPPA 5024 Query: 1577 NEDIKQKHKVGDEWLVT-----AVIEGIPPPEVIWYKNGNKLENDKEYNITTK-EKTSVI 1630 +I VG + VT A G P E + + + END + I ++T I Sbjct: 5025 APEILTA--VGSDETVTVTWNLAATNGAPVTEYELHYSIDGFENDIDNIIVVATQETGPI 5082 Query: 1631 R--IKELKRSHSSKYTIEASNTAGTSSVEVTLKV--YDKPSKPEGPVIMREISRESVTIE 1686 +++L+ + + + + A++ A TL + P+ P R VT++ Sbjct: 5083 SYPVEDLENARTYSFKVRANSIASFGPFSNTLDAVPFTTPNAPTDLEATR--GNGEVTLQ 5140 Query: 1687 WKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 W P +GG +T Y +E + + D T I L+ Y FRV A Sbjct: 5141 WNKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAV 5200 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N G E S+ I T VP+ +ESV + W PSE GG +IDY + Sbjct: 5201 NAAG--EGALSD-IATATPATVPAAPTLDTATPG--DESVLLGWTPSENTGGDALIDYLI 5255 Query: 1805 EIKQ------EGKKWKXXXXXXX-----XXARIQKLSINTTYQFRIYARNEI-GTSLPYT 1852 + ++ W I L+ TY+FR++A+N + G SLP Sbjct: 5256 QFRELDATNDAESNWTTFDEGNGGVNVLTSITIDDLTNGVTYEFRVFAKNTVPGQSLP-- 5313 Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKGK 1910 + + + PS PR+ V+ V++ W P NGG I Y +++ Sbjct: 5314 --SNVLSAEPSSAPSVPRDLRVTNIGDEFVSISWLAPADNGGDDIVGYTVQYSDDNFTTI 5371 Query: 1911 SWTKIVTVGGSV-HEHCIENIKEKDEIIFRISAEN-TVGVSLPTES--QSVRLEKHATVP 1966 S +IV V G + + + +++ + FR+ A N +P S TVP Sbjct: 5372 STQEIVPVSGVLPTDATVSSLENGVDYQFRVIAHNEDDDPQIPDSSDPSDPVTGTPGTVP 5431 Query: 1967 SPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-------AIRDVTKTMWMEVGKV 2019 PT + + G+ I + W P DGG + GY I A +VT T Sbjct: 5432 GIPTDLVATTLSGTEIQLV-WQAPSDDGGRAVSGYLIERLGTDGAFAEVTTTTIPVPESP 5490 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + F LS TY R+ A N +G +P ++D+ Sbjct: 5491 TASDTTFTDTGLSLGTTYTYRVSAVNVLGTGDPSDTDD 5528 Score = 129 bits (311), Expect = 9e-28 Identities = 126/487 (25%), Positives = 205/487 (42%), Gaps = 36/487 (7%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 E+ + +G +N ++ + + L + + + A N G SS L Sbjct: 1502 EIQYSTDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENG-SSPPSNLDT 1560 Query: 1663 YDKPSKPEGPVI---MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 + P+ PVI E VTI W P + GG +T Y I+ +P W V+ Sbjct: 1561 ATPATIPDAPVIDPAQTVTGNEFVTIAWSTPYN-GGSPITHYVIQV-KPAGGSWETVSSN 1618 Query: 1720 DRDVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778 D + IQ L E+ FRV A N G ++ S I + T DVP+ Sbjct: 1619 FNDPQNILTIQNLENGVEHSFRVAAVN--GVNQGPYSA-IELATPGDVPAQILDLSVERG 1675 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQ-EGKK---WKXXXXXXXXXARIQKLSINTT 1834 +E V +TW + N G PI DY +E+ +G + + L Sbjct: 1676 --DEQVLLTW-SAPNNHGFPITDYVIEVDYGDGNGFVVYNDGQSIDTTDVPVTGLENGVL 1732 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS--VTLKWTEPESN 1892 ++FR+YA N +G + P + TP P V++E + + + W+ P+ + Sbjct: 1733 HKFRVYAVNALGNATPSNEVEA-------TPARAPDAPVITELNAGDGQIEVIWSTPD-D 1784 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSL 1950 GG I Y +E+ T S VT+ G+ + + + + D FR+ A N V S Sbjct: 1785 GGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTYYFRVIAINDVDESD 1844 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 P++ +S TVP+ P L +VG + + SW P DGG+PL GY ++I DVT Sbjct: 1845 PSDVESAI---PVTVPAKPV--LNTPVVGDSSLTVSWSAPN-DGGSPLTGYTLSITDVTG 1898 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV-IPGEGSHA 2069 + N + +N +L+ +TY + A N G S+P ++ + PG+ Sbjct: 1899 GNTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDPSDAVTGIPIGAPGQIDDL 1958 Query: 2070 DEEPGEQ 2076 E G++ Sbjct: 1959 GAESGDK 1965 Score = 127 bits (307), Expect = 3e-27 Identities = 119/487 (24%), Positives = 191/487 (39%), Gaps = 41/487 (8%) Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKE-----LKRSHSSKYTIEASNTAGTSSVE--VTLK 1661 +G K+E + N T +T+ + + L+ + Y I A N GT + + Sbjct: 8310 SGYKIEQSTDNNTWTVLETTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASDVASAT 8369 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE-------LTKYAIEKHEPDNNRWI 1714 D P P + VT+ W P DGG+ +T Y + + D N W Sbjct: 8370 PLDVPGPPRN--LQTTPGNAQVTLAWDIPSTDGGITADNGGSIITGYVVH-YAIDTNFWK 8426 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 + T + L Y FRV A N VGF L + + + VP Sbjct: 8427 TFNEEPITERTVDVTGLTNGQNYKFRVFAVNEVGF---LHPSLVSSEIPVTVPERPWGLT 8483 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-----WKXXXXXXXXXARI--- 1826 N+ + ++W NGGS I YK++ K GK W Sbjct: 8484 ITAPSQNQ-INLSWKTPLDNGGSTITGYKIQ-KTIGKPTTNSVWSDAPSGTLGTVNSWSD 8541 Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 L TTY +R+ + S TL+ P PRN + E+ + + + W Sbjct: 8542 TNLIPGTTYSYRVITLTDAVPDGDSNSASGAIFATTLSVPGAPRNLTL-EAEGKKIVIDW 8600 Query: 1887 TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAEN 1944 P SNGG+PI NY+I++ G W + +V ++ NI E R+ AEN Sbjct: 8601 VAPTSNGGTPIVNYLIQWSDNGGSKWNTLKRDASAVTSATVKSSNIVLGTEYQIRVYAEN 8660 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA 2004 T+G P + SV+ T+P+ P + + G V+ SW P DGG+ + Y + Sbjct: 8661 TIG---PGPASSVKSVTPTTIPTAPRSLVTDPQDGQ--VVLSWSKPLSDGGSAITDYLVR 8715 Query: 2005 IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064 + ++ + + L+ + TY R+ A N +G + P + + V G Sbjct: 8716 YSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRVVAVNSVG-NSPASTGK--SVAVG 8772 Query: 2065 EGSHADE 2071 EG+ ++E Sbjct: 8773 EGNSSEE 8779 Score = 124 bits (300), Expect = 2e-26 Identities = 172/699 (24%), Positives = 270/699 (38%), Gaps = 67/699 (9%) Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEY--QEIDTTEWISVKNI----TK 1435 PGK I+ + ++ + + W EP N G + I Y +EY E D + ++ + Sbjct: 4435 PGKTEIISLTPGNAQVEVEWSEPTN-GGTPITGYRIEYTTNETDANNGVFTSSVDVAASP 4493 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDI---SDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 +I NL +Y FR A N VD SD T T + + + + Sbjct: 4494 LSATINNLNNGDTYYFRVTATNSVDFGEPSDVDSATPARAPDAPTDLVATLGDGQVTIGF 4553 Query: 1493 TEPNEDIELTCIFGGVPQPKVT---WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 T P ED I + W+ + T T E ++ Sbjct: 4554 TPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQ--TESTTPE----ITVTGLNNGQEYLFR 4607 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNE-DI---KQKHKVGDEWLVTAVIEGIPPPE-V 1604 +A N G + S V + + P N D+ + +V W AV G+P + Sbjct: 4608 AVAVNGVGPGDES--VPVAETPAALSGNPTDLVATRGNTQVSLTWAAPAVTGGVPVTSYI 4665 Query: 1605 IWYK---NGNKLENDKEYNITTKE---KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + Y NG+ N +T++ T+ I I L+ + + + A NTAG S Sbjct: 4666 VEYTDDANGDFGANPSSQTVTSETLPVPTNTI-INGLQNGVTYTFRVIAVNTAGPSGPSN 4724 Query: 1659 TLKVYDKPSK-PEGPVIMR-EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN--NRWI 1714 T KP+ P+ P + S +V + W P + GG + +Y I+ ++ Sbjct: 4725 TDTA--KPATVPDAPTFDDPQPSAGTVGLSWTPG-NTGGEPIERYRIDYTSANSFVEGQY 4781 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 + V I+ L EY FR+ A+N VGF + S PI T +D PS Sbjct: 4782 QSEFVTHPTTVVDIEDLENGVEYQFRISAENEVGFGD--PSAPIT-ATPVDGPSQVTGLS 4838 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXX----XXXARIQKLS 1830 N V ++W +GG I Y +E ++G A I L Sbjct: 4839 GQR--GNGEVSLSW-SEPFDGGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLE 4895 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 TY+FR+YA+N+I P ++ +T TPP+ ++ S V+L WT Sbjct: 4896 NGVTYEFRVYAQNDIDDG-PVSTTISVTPATVPTPPTN----LIPTFGSTQVSLGWTASS 4950 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 +GGS I +YI+EFK W V + + FR+ A N VG S Sbjct: 4951 DDGGSDIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVGNSD 5010 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL----LGYNIAIR 2006 P+E K AT +PP AP + VGS+ +T GAP+ L Y+I Sbjct: 5011 PSE------VKEATPAAPPAAPEILTAVGSDETVTVTWNLAATNGAPVTEYELHYSIDGF 5064 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 + + V + + + + DL TY ++ A + Sbjct: 5065 ENDIDNIIVVATQETGPISYPVEDLENARTYSFKVRANS 5103 Score = 122 bits (295), Expect = 8e-26 Identities = 115/435 (26%), Positives = 179/435 (41%), Gaps = 29/435 (6%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE--ISRESVTIEWKP 1689 I L S +TI A N G S + + +KP+ P + IS + + W Sbjct: 5993 IDGLDNGVSYTFTISARNDVG-SGPDSAPETVIPAAKPDVPTDLEAEAISGTEIDLTWLA 6051 Query: 1690 PLDDGGLELTKYAIEKHEPDNN-RWIKVADVD----RDVETYCIQKLNENCEYMFRVIAQ 1744 P++ GGL +T Y IE+H+ D N + V D T+ L Y +R+ A Sbjct: 6052 PVNTGGLGITGYLIERHDGDGNFATVTTTSVSVPPSTDDTTFNDTGLELGTTYTYRISAI 6111 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 G + S+P T +VP + N + I W NGGSP+ Y V Sbjct: 6112 TGAGTGSS--SQP-ASDTTFNVPDKPTITEVN--VGNNELEIVWTAPTDNGGSPVTSYTV 6166 Query: 1805 EIK-QEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 E K W+ A + L Y+FR+YA + +GTSLP SD + G Sbjct: 6167 EYKLTTDNTWQLSPVPPADGALDVTVIGLENGEEYEFRVYAISTVGTSLP--SD--VATG 6222 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-GKSWTKIVTVG 1919 T PS P N V + + V+L W P +GGS I +Y++E+ + + +T V Sbjct: 6223 IPATTPSAPLNVVATRGDTE-VSLTWDLPADDGGSAIRDYLVEYASAELNLIYTPFVEPE 6281 Query: 1920 GSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 S + + E FR+ A N + + +V + A P+ P+ ++ Sbjct: 6282 ESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG---DYSAVTADSAAVPAGDPSTPVISTVI 6338 Query: 1979 GSN-IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 + +V +W + +GG L+ Y I T +E + L +N+ DL Y Sbjct: 6339 ADDELVNLTWLASDANGGNNLV-YRIETSTDGFTTLIEDPAPTTSNLVYNVDDLQNGQEY 6397 Query: 2038 MIRIYARNEIGLSEP 2052 RI A + G S+P Sbjct: 6398 SFRITAITDAGSSDP 6412 Score = 122 bits (294), Expect = 1e-25 Identities = 172/711 (24%), Positives = 267/711 (37%), Gaps = 74/711 (10%) Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 E++ T LD P P + D + + W +PE+T ++ Y +E + V+ Sbjct: 7993 EVSTTTLDLPDEPTSLQVFA-DRGQLTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVE 8051 Query: 1432 NITKTQT--SIQNLKTNSSYRFRAYAVNEVDISDASET---TEYYKVIKETKIQSPTVEK 1486 N +T + L N+SY +R + SD S+ T Y +++ +K Sbjct: 8052 NTDSDETIYTDSGLNDNTSYSYRVSTITAAGTSDPSQIVRGTTYGLPSAPLDLEADAKKK 8111 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK--ATYEN----RXXXXXXXX 1540 ++ T P D GG P +T Y+ KL T + Y + + Sbjct: 8112 KVRLSWTAPVND-------GGSP---ITDYKIEYKLATDTNWSVYADAERIKPQATVDSL 8161 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK-QKHKVGDEWLVTAVIEGI 1599 ++ A N+ G TS +V Q KP + + Q+ G + + E Sbjct: 8162 TNSKIYQFRVSAVNEFGAGLTSSIV--QAKPSVAGATAAYNIQEIPSGQDVFLPHNAEDT 8219 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 +NG KL K I K S I + + + + ++ Sbjct: 8220 -------LENGGKLAGLK---IKPKNTLSEIAMTSTFTKDAPTGVTQEAKMYLKFELDFV 8269 Query: 1660 LKVYDKPSKPEGPV--IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 V S P G V ++ S V + W P DGG +++ Y IE+ DNN W + Sbjct: 8270 EDVETDASVP-GQVTSVVATASAGKVELTWSAPDSDGGADISGYKIEQ-STDNNTWTVLE 8327 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 Y L Y +R+ A N G A + + T LDVP Sbjct: 8328 TTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASD---VASATPLDVPGPPRNLQTTP 8384 Query: 1778 XIDNESVYITW-FPS------EKNGGSPIIDYKVEIKQEGKKWKXXXX--XXXXXARIQK 1828 N V + W PS NGGS I Y V + WK + Sbjct: 8385 --GNAQVTLAWDIPSTDGGITADNGGSIITGYVVHYAIDTNFWKTFNEEPITERTVDVTG 8442 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 L+ Y+FR++A NE+G P +I + T P +P ++ + + L W Sbjct: 8443 LTNGQNYKFRVFAVNEVGFLHPSLVSSEIPV----TVPERPWGLTITAPSQNQINLSWKT 8498 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVG------GSVHEHCIENIKEKDEIIFRISA 1942 P NGGS IT Y I+ KT+ GK T V G+V+ N+ +R+ Sbjct: 8499 PLDNGGSTITGYKIQ-KTI-GKPTTNSVWSDAPSGTLGTVNSWSDTNLIPGTTYSYRVI- 8555 Query: 1943 ENTVGVSLPT-ESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 T+ ++P +S S AT S P AP L + G IV+ W P +GG P++ Sbjct: 8556 --TLTDAVPDGDSNSASGAIFATTLSVPGAPRNLTLEAEGKKIVI-DWVAPTSNGGTPIV 8612 Query: 2000 GYNIAIRDVTKTMW--MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 Y I D + W ++ V + ++ Y IR+YA N IG Sbjct: 8613 NYLIQWSDNGGSKWNTLKRDASAVTSATVKSSNIVLGTEYQIRVYAENTIG 8663 Score = 118 bits (285), Expect = 1e-24 Identities = 110/418 (26%), Positives = 171/418 (40%), Gaps = 32/418 (7%) Query: 1642 KYTIEASNTAG---TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 ++TI A+N G T S T + P+ G + + V +EW P+ + G E+ Sbjct: 3307 EFTITATNEHGLTSTPSAPATATPFGPPNAVTG--LGATPGDKQVDLEWTEPVPNAGGEI 3364 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y I +P+ N ++ ++ + I LN EY F + A N G + + Sbjct: 3365 ASYTITVTDPNGNV-VQTITINAPADEANIDGLNNGVEYTFTITATNVNGVT----GDAA 3419 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE-----GKKW 1813 I TA+ N+SV ++W P + + GS I Y ++ + G Sbjct: 3420 TI-TAIPATVPLPPVLDSADRGNQSVTLSWTP-QFDQGSTITQYTIQYSSDNFQTTGTVV 3477 Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 I L+ TYQF++ A N G S P I K T P P Sbjct: 3478 IGDDEALATSTTISGLTNGLTYQFQVIASNAFGPSDP----SNIKSAKPATFPDAP-TLD 3532 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGS--VHEHCIENI 1930 ++ ++SV L WT P +NGG PI +Y +E+ + S T+ G+ + + + Sbjct: 3533 SADRGNQSVALSWT-PGNNGGEPIDSYHVEWSEDENFASILDTATISGNPPAESYTVTGL 3591 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 D FRI + N + S P+ +V + AT PS P P G N V SW P Sbjct: 3592 TNGDTYYFRIISSNVIDDSAPS---NVLSQTPATTPSEPLNPAA--EPGPNQVEVSWTLP 3646 Query: 1991 EWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 DGGA + Y + W E + NT I +L+ Y+ I+A N++G Sbjct: 3647 ASDGGAEI-EYYVVRYSTDGGSWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHNDVG 3703 Score = 115 bits (277), Expect = 1e-23 Identities = 105/393 (26%), Positives = 156/393 (39%), Gaps = 30/393 (7%) Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREIS 1679 IT I L +TI A+N G + T+ + P PV+ + Sbjct: 3382 ITINAPADEANIDGLNNGVEYTFTITATNVNGVTGDAATITAIPA-TVPLPPVLDSADRG 3440 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW---IKVADVDRDVETYCIQKLNENCE 1736 +SVT+ W P D G +T+Y I+ + DN + + + D + + I L Sbjct: 3441 NQSVTLSWTPQFDQGST-ITQYTIQ-YSSDNFQTTGTVVIGDDEALATSTTISGLTNGLT 3498 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y F+VIA N G S+P IK+A N+SV ++W P NGG Sbjct: 3499 YQFQVIASNAFG-----PSDPSNIKSAKPATFPDAPTLDSADRGNQSVALSWTPGN-NGG 3552 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXX------XARIQKLSINTTYQFRIYARNEIGTSLP 1850 PI Y VE ++ + L+ TY FRI + N I S P Sbjct: 3553 EPIDSYHVEWSEDENFASILDTATISGNPPAESYTVTGLTNGDTYYFRIISSNVIDDSAP 3612 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 + T PS+P N +E V + WT P S+GG+ I Y++ + T G Sbjct: 3613 ----SNVLSQTPATTPSEPLN-PAAEPGPNQVEVSWTLPASDGGAEIEYYVVRYST-DGG 3666 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 SWT+ T G+ I+ + +F I A N VG ++ + AT PS P Sbjct: 3667 SWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTA---TPATAPSAPQ 3723 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 + G V+ W P +GGA + Y + Sbjct: 3724 NLVATPQTGQ--VLLVWEKPSSNGGATITSYTV 3754 Score = 115 bits (276), Expect = 2e-23 Identities = 103/414 (24%), Positives = 158/414 (38%), Gaps = 26/414 (6%) Query: 1645 IEASNTAG--TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 + A+N G S+ + + + P KP + + VT+ W P+++GG E+T Y Sbjct: 7781 VSAANAGGISNSTSPIPVSAFTIPGKPFD--LTTQFGDSQVTLLWSAPVNNGGEEITNYV 7838 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 IE + W D T + L EY FRV A+N G + KT Sbjct: 7839 IEYSSDNGANWNVFDDGTSADPTATVTGLTNGQEYKFRVSAENIAGVG-------LPSKT 7891 Query: 1763 ALDVPSXXXXXXXXXXIDN--ESVYITW-FPSEKNGGSPIIDYKVEIKQEG---KKWKXX 1816 A DVP+ +S+ ITW P + G + I Y +E + Sbjct: 7892 ASDVPATQSSRPTGLSATPALDSITITWNAPEDIGGATEISGYVIERSISSGFFNPYVDD 7951 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG-KTLTPPSQPRNFVVS 1875 L T Y +RI A + + P D + TL P +P + V Sbjct: 7952 TGSALTSFVDTSLFSGTDYSYRIAAITLLPSGEPVVGDFSGEVSTTTLDLPDEPTSLQVF 8011 Query: 1876 ESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + +TL W +PE G P+ Y IE ++ + T + + + + Sbjct: 8012 ADRGQ-LTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVENTDSDETIYTDSGLNDNTS 8070 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDG 1994 +R+S G S P SQ VR T P+APL++ V SW P DG Sbjct: 8071 YSYRVSTITAAGTSDP--SQIVR----GTTYGLPSAPLDLEADAKKKKVRLSWTAPVNDG 8124 Query: 1995 GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 G+P+ Y I + T T W + + + L+ + Y R+ A NE G Sbjct: 8125 GSPITDYKIEYKLATDTNWSVYADAERIKPQATVDSLTNSKIYQFRVSAVNEFG 8178 Score = 113 bits (272), Expect = 5e-23 Identities = 111/445 (24%), Positives = 181/445 (40%), Gaps = 23/445 (5%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 N+T T+V + +L + I N AG + + P P + E + Sbjct: 6692 NVTPANSTAVT-VTDLINGFQYFFRISGVNIAGIGEPS-EFRATTPATLPSAPRDL-EAT 6748 Query: 1680 RE--SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCE 1736 R+ SV + W P D GG L+ Y +E P + WIK D +T + L + Sbjct: 6749 RDNTSVHLTWNVPEDLGGAPLSAYMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQ 6808 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y FR+ A+N ++ + V T P+ N ++W E NGG Sbjct: 6809 YQFRITAKN-TAITDFGPASDTVSATPATTPTAPRDLVVIAG--NNQATLSWNVPESNGG 6865 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTS 1853 I DYK+EI+ G+ W + I L+ TY+FR+ A N + P + Sbjct: 6866 DSITDYKIEIRIAGQDWDVYDDGVSTTTQGIVIPNLTNGVTYEFRVTAINSVN---PGPA 6922 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT-VKGKSW 1912 D + GK T P+ P+ VV ++ + + WT+P +NGGS IT+Y++++ T + Sbjct: 6923 SD-VVPGKPATIPTPPKKLVVIPGDTK-LDVTWTKPTNNGGSAITSYLVQYSTDGTFDAS 6980 Query: 1913 TKIVTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA 1971 T VTV + I ++ I +++A N VG S P + ++ S Sbjct: 6981 TPSVTVTDLTNLMVTISGLENDVPIHVQVTAINGVGSSGPAGP----VIGVPSLGSSSPV 7036 Query: 1972 PLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031 L + V SW P+ G L G+ + D + D L F L Sbjct: 7037 GLFADAISDTEVFVSWSPPQELGDRTLEGFVLERLDANGNVLETFTINDPTKLDFTDTGL 7096 Query: 2032 SENHTYMIRIYARNEIGLSEPLESD 2056 TY ++ A + ++ ++SD Sbjct: 7097 LPGTTYKYQVSALLSLEGADTVQSD 7121 Score = 111 bits (267), Expect = 2e-22 Identities = 96/345 (27%), Positives = 140/345 (40%), Gaps = 25/345 (7%) Query: 1669 PEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETY 1726 P P + E E V + W PP +GG +T Y IE + D N W D D Sbjct: 1280 PGAPTNLTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFNDGTSTDTTDV 1337 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L Y FRV A N G +A + I T VP N VY+ Sbjct: 1338 AVTGLTNGQSYDFRVSAVNTEGTGDASD---IATATPAGVPDAPVIDEALG--GNGQVYL 1392 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 TW N G+ I DY +E+ +G W+ + L TY FR+ A N Sbjct: 1393 TW-EHPPNNGAAITDYIIEV-NDGNGWEVFNDGTSTNRFVTVDNLENGETYSFRVKAVNS 1450 Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 G P+++ T T T P +S V + W P +GGS I++Y I++ Sbjct: 1451 AGEG-PFSTPVTATPSSTATAPFL-HTLTPGDS---EVFVDWDAPNDDGGSTISSYEIQY 1505 Query: 1905 KT-VKGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 T T VTV G+ + E+ + + FR+ A N G S P+ + Sbjct: 1506 STDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENGSSPPSNLDTA---T 1562 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 AT+P P + G+ V +W TP ++GG+P+ Y I ++ Sbjct: 1563 PATIPDAPVIDPAQTVTGNEFVTIAWSTP-YNGGSPITHYVIQVK 1606 Score = 110 bits (265), Expect = 4e-22 Identities = 113/416 (27%), Positives = 173/416 (41%), Gaps = 43/416 (10%) Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD------NNRWIKVADVDRDVE-T 1725 ++ +S + + W+ P DDGG ++ Y IE+ D I V + + T Sbjct: 5437 LVATTLSGTEIQLVWQAPSDDGGRAVSGYLIERLGTDGAFAEVTTTTIPVPESPTASDTT 5496 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 + L+ Y +RV A N +G + +++ T D PS NE V Sbjct: 5497 FTDTGLSLGTTYTYRVSAVNVLGTGDPSDTDD---ATTFDYPSAPVLDAAIR--GNELVT 5551 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXAR----IQKLSINTTYQFRIY 1840 + W NGG+P+ +Y + + G W L+ TY+FR+ Sbjct: 5552 LQWTAPSDNGGTPLENYIAQFRLLGASDWTTFDDEISLSPTEINVDSGLTNGQTYEFRVI 5611 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N +G S + K T PS+P V +E R V+L W EPE +GG I +Y Sbjct: 5612 AENSVGES----EASNVLQAKPATTPSKPLQ-VGAEFGDRQVSLTWLEPEISGGEDIFDY 5666 Query: 1901 IIEFKTVK---GKSWTKIVTVGGSVHEH---CIENIKEKDEIIFRISAENTVGVSLPTES 1954 I+EF+ SW G V+ + I + FR+SAEN VGV + Sbjct: 5667 ILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAENDVGVG---DV 5723 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIA-------IRD 2007 V AT + PTA + G+ I + SW P+ GG + GY I D Sbjct: 5724 SDVATATPATASNAPTALSATAISGTEITL-SWIAPQNTGGFAITGYLIERHDGDGNFDD 5782 Query: 2008 VTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI--GLSEPLESDEPFKV 2061 VT T+ + + + +T F LS+ TY R+ A ++ G++ +SD F V Sbjct: 5783 VT-TLSVSLPPLPTDT-TFTDTGLSQGTTYTYRVSAVTQLGPGIASGTDSDTTFDV 5836 Score = 109 bits (262), Expect = 8e-22 Identities = 151/707 (21%), Positives = 265/707 (37%), Gaps = 61/707 (8%) Query: 1384 PGKPNIL--EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ--TS 1439 PGKP L + S + + W P N G I YV+EY + W + T + Sbjct: 7804 PGKPFDLTTQFGDSQVTLLWSAPVNNGGEEITNYVIEYSSDNGANWNVFDDGTSADPTAT 7863 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN--E 1497 + L Y+FR A N + S+T + ++ + L +IT N E Sbjct: 7864 VTGLTNGQEYKFRVSAENIAGVGLPSKTASDVPATQSSRPTGLSATPALDSITITWNAPE 7923 Query: 1498 DIE-LTCIFGGVPQPKVTW-----YRD--GKKLKT-AKATYENRXXXXXXXXXXXXXXXY 1548 DI T I G V + ++ Y D G L + + + Sbjct: 7924 DIGGATEISGYVIERSISSGFFNPYVDDTGSALTSFVDTSLFSGTDYSYRIAAITLLPSG 7983 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 + + + GEV T+ + + +P S + + ++ W+ G+P V+ Y+ Sbjct: 7984 EPVVGDFSGEVSTT-TLDLPDEPT---SLQVFADRGQLTLTWIDPEDTSGLP---VLGYE 8036 Query: 1609 NGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK--VYD 1664 + + I T ++ L + S Y + AGTS ++ Y Sbjct: 8037 IERRSTGAEFTTIVENTDSDETIYTDSGLNDNTSYSYRVSTITAAGTSDPSQIVRGTTYG 8096 Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 PS P + + ++ V + W P++DGG +T Y IE + W AD +R Sbjct: 8097 LPSAPLD--LEADAKKKKVRLSWTAPVNDGGSPITDYKIEYKLATDTNWSVYADAERIKP 8154 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + L + Y FRV A N F L S +++ V + V Sbjct: 8155 QATVDSLTNSKIYQFRVSAVNE--FGAGLTSS--IVQAKPSVAGATAAYNIQEIPSGQDV 8210 Query: 1785 YITWFPSE--KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 ++ + +NGG + K++ K + T + ++Y + Sbjct: 8211 FLPHNAEDTLENGGK-LAGLKIKPKN------TLSEIAMTSTFTKDAPTGVTQEAKMYLK 8263 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 E L + D + + P Q + V + S + V L W+ P+S+GG+ I+ Y I Sbjct: 8264 FE----LDFVED----VETDASVPGQVTSVVATASAGK-VELTWSAPDSDGGADISGYKI 8314 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 E ++ +WT + T ++ +++ +RISA N G ++ S Sbjct: 8315 E-QSTDNNTWTVLETTTCQCTDYTDNSLENGQTYYYRISAINAKGTGTASDVASA---TP 8370 Query: 1963 ATVPSPP----TAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 VP PP T P ++ + +I T G +GG+ + GY + + W Sbjct: 8371 LDVPGPPRNLQTTPGNAQVTLAWDIPSTDGGITADNGGSIITGY-VVHYAIDTNFWKTFN 8429 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP-LESDEPFKVIP 2063 + + ++ L+ Y R++A NE+G P L S E +P Sbjct: 8430 EEPITERTVDVTGLTNGQNYKFRVFAVNEVGFLHPSLVSSEIPVTVP 8476 Score = 109 bits (261), Expect = 1e-21 Identities = 115/461 (24%), Positives = 185/461 (40%), Gaps = 42/461 (9%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWKPP 1690 I L+ + ++ + A N V T+ V + P P ++ V++ W Sbjct: 4891 IGNLENGVTYEFRVYAQNDIDDGPVSTTISV-TPATVPTPPTNLIPTFGSTQVSLGWTAS 4949 Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 DDGG ++ Y +E + W D DV + L Y FRV A N VG Sbjct: 4950 SDDGGSDIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVG-- 5007 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 S+P +K A +E+V +TW + N G+P+ +Y++ +G Sbjct: 5008 ---NSDPSEVKEATPAAPPAAPEILTAVGSDETVTVTWNLAATN-GAPVTEYELHYSIDG 5063 Query: 1811 KKWKXXXXXXXXXAR-------IQKLSINTTYQFRIYARNEIGTSLPYTSD-DKITIGKT 1862 + ++ L TY F++ A N I + P+++ D + Sbjct: 5064 FENDIDNIIVVATQETGPISYPVEDLENARTYSFKVRA-NSIASFGPFSNTLDAV----P 5118 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK--TVKGKSWTKIVTVGG 1920 T P+ P + + VTL+W +P+ NGGS IT+Y++E+ + ++ VT Sbjct: 5119 FTTPNAPTDLEATRGNG-EVTLQWNKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSD 5177 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 I + FR+ A N G ++ + ATVP+ PT L+ G Sbjct: 5178 DPITTVISGLDNGTLYSFRVKAVNAAGEGALSD---IATATPATVPAAPT--LDTATPGD 5232 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-----MW--MEVGKVDVNTL-KFNIRDLS 2032 V+ W E GG L+ Y I R++ T W + G VN L I DL+ Sbjct: 5233 ESVLLGWTPSENTGGDALIDYLIQFRELDATNDAESNWTTFDEGNGGVNVLTSITIDDLT 5292 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEP 2073 TY R++A+N + P +S P V+ E S A P Sbjct: 5293 NGVTYEFRVFAKNTV----PGQS-LPSNVLSAEPSSAPSVP 5328 Score = 106 bits (254), Expect = 8e-21 Identities = 118/471 (25%), Positives = 177/471 (37%), Gaps = 44/471 (9%) Query: 1630 IRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 + + L + ++ + A N G +S T + P G + IS + +EW Sbjct: 4299 VTVTGLTNGLTYEFRVSAENAVDVGPTSNVATARPATLSDAPTG-LDAEAISDTEIDLEW 4357 Query: 1688 KPPLDDGGLELTKYAIEKH-EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 PL GG + Y IE+ E + + I VAD TY L+ Y +RV A Sbjct: 4358 NAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAAITD 4417 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 G + + T DVP N V + W NGG+PI Y++E Sbjct: 4418 AGVGDTSSTAEA---TTFDVPGKTEIISLTPG--NAQVEVEW-SEPTNGGTPITGYRIEY 4471 Query: 1807 KQEGKKWKXXXXXXXX-------XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 A I L+ TY FR+ A N + P + D T Sbjct: 4472 TTNETDANNGVFTSSVDVAASPLSATINNLNNGDTYYFRVTATNSVDFGEP-SDVDSATP 4530 Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTV 1918 + P P + V + + VT+ +T P +GGS I +Y IE+ G +W + Sbjct: 4531 ARA---PDAPTDLVATLGDGQ-VTIGFTPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQT 4586 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 + E + + E +FR A N VG P + E A + PT + R Sbjct: 4587 ESTTPEITVTGLNNGQEYLFRAVAVNGVG---PGDESVPVAETPAALSGNPTDLVATR-- 4641 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRD----------VTKTMWMEVGKVDVNTLKFNI 2028 G+ V +W P GG P+ Y + D ++T+ E V NT+ I Sbjct: 4642 GNTQVSLTWAAPAVTGGVPVTSYIVEYTDDANGDFGANPSSQTVTSETLPVPTNTI---I 4698 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESD--EPFKVIPGEGSHADEEPGEQT 2077 L TY R+ A N G S P +D +P +P + D +P T Sbjct: 4699 NGLQNGVTYTFRVIAVNTAGPSGPSNTDTAKP-ATVPDAPTFDDPQPSAGT 4748 Score = 106 bits (254), Expect = 8e-21 Identities = 113/477 (23%), Positives = 190/477 (39%), Gaps = 41/477 (8%) Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 V+ Y + + + + +T + I L + ++A N AG ++ + Sbjct: 5156 VVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAVNAAGEGALS-DIATA 5214 Query: 1664 DKPSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPD-----NNRWIKVA 1717 + P P + ESV + W P + GG L Y I+ E D + W Sbjct: 5215 TPATVPAAPTLDTATPGDESVLLGWTPSENTGGDALIDYLIQFRELDATNDAESNWTTFD 5274 Query: 1718 DVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 + + V + I L Y FRV A+N V ++L S + + + PS Sbjct: 5275 EGNGGVNVLTSITIDDLTNGVTYEFRVFAKNTVP-GQSLPSNVLSAEPS-SAPSVPRDLR 5332 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG------KKWKXXXXXXXXXARIQK 1828 I +E V I+W NGG I+ Y V+ + ++ A + Sbjct: 5333 VTN-IGDEFVSISWLAPADNGGDDIVGYTVQYSDDNFTTISTQEIVPVSGVLPTDATVSS 5391 Query: 1829 LSINTTYQFRIYARNE-IGTSLPYTSD--DKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 L YQFR+ A NE +P +SD D +T G T P P + V + + + L Sbjct: 5392 LENGVDYQFRVIAHNEDDDPQIPDSSDPSDPVT-GTPGTVPGIPTDLVATTLSGTEIQLV 5450 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIEN--------IKEKDEII 1937 W P +GG ++ Y+IE G ++ ++ T V E + + Sbjct: 5451 WQAPSDDGGRAVSGYLIERLGTDG-AFAEVTTTTIPVPESPTASDTTFTDTGLSLGTTYT 5509 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGA 1996 +R+SA N +G P+++ AT P+AP L+ + G+ +V W P +GG Sbjct: 5510 YRVSAVNVLGTGDPSDTDD------ATTFDYPSAPVLDAAIRGNELVTLQWTAPSDNGGT 5563 Query: 1997 PLLGYNIAIRDVTKTMWMEV-GKVDVNTLKFNI-RDLSENHTYMIRIYARNEIGLSE 2051 PL Y R + + W ++ ++ + N+ L+ TY R+ A N +G SE Sbjct: 5564 PLENYIAQFRLLGASDWTTFDDEISLSPTEINVDSGLTNGQTYEFRVIAENSVGESE 5620 Score = 104 bits (250), Expect = 2e-20 Identities = 159/693 (22%), Positives = 259/693 (37%), Gaps = 67/693 (9%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICW 1401 S TI + N D +++ N+ + +V P P + + + I + Sbjct: 4495 SATINNLNNGDTYYFRVTATNSVDFGEPS-DVDSATPARAPDAPTDLVATLGDGQVTIGF 4553 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT---SIQNLKTNSSYRFRAYAVNE 1458 P G S II Y +EY + W + T++ T ++ L Y FRA AVN Sbjct: 4554 TPPVEDGGSDIIDYYIEYSVDNGDNWFEFNDQTESTTPEITVTGLNNGQEYLFRAVAVNG 4613 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT----CIFGGVPQPK-V 1513 V D S + + + P + T N + LT + GGVP + Sbjct: 4614 VGPGDES--------VPVAETPAALSGNPTDLVATRGNTQVSLTWAAPAVTGGVPVTSYI 4665 Query: 1514 TWYRD------GKKLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 Y D G + T E ++ IA N G S Sbjct: 4666 VEYTDDANGDFGANPSSQTVTSETLPVPTNTIINGLQNGVTYTFRVIAVNTAGPSGPSNT 4725 Query: 1565 VGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPE--VIWYKNGNKLENDKEYN 1620 + V D Q VG W T G P E I Y + N + + Sbjct: 4726 DTAKPATVPDAPTFDDPQPSAGTVGLSW--TPGNTGGEPIERYRIDYTSANSFVEGQYQS 4783 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREI 1678 T+V+ I++L+ ++ I A N G S +T D PS+ G + + Sbjct: 4784 EFVTHPTTVVDIEDLENGVEYQFRISAENEVGFGDPSAPITATPVDGPSQVTG--LSGQR 4841 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 V++ W P DGG+ + Y IE + N + V I L Y Sbjct: 4842 GNGEVSLSWSEPF-DGGVTIDTYVIEYSKDGFANTLTQTVTGLPPVTNAVIGNLENGVTY 4900 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 FRV AQN + + S I + T VP+ + V + W S +GGS Sbjct: 4901 EFRVYAQNDI--DDGPVSTTISV-TPATVPT--PPTNLIPTFGSTQVSLGWTASSDDGGS 4955 Query: 1798 PIIDYKVEIKQEGKK-WKXXXXXXXX--XARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 I DY VE K + + W+ A + L+ Y+FR+ A N++G S P Sbjct: 4956 DIDDYIVEFKLKSESDWQVFNDGVSDVPGATVTGLTNGQIYEFRVKAHNDVGNSDP---- 5011 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG--KSW 1912 ++ PP+ P + + + +VT+ W +N G+P+T Y + + ++ G Sbjct: 5012 SEVKEATPAAPPAAP-EILTAVGSDETVTVTWNLAATN-GAPVTEYELHY-SIDGFENDI 5068 Query: 1913 TKIVTVG----GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 I+ V G + + +E+++ F++ A N++ P + + T P+ Sbjct: 5069 DNIIVVATQETGPI-SYPVEDLENARTYSFKVRA-NSIASFGPFSNTLDAVP--FTTPNA 5124 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 PT LE G+ V W P+++GG+ + Y Sbjct: 5125 PT-DLEATR-GNGEVTLQWNKPDFNGGSLITSY 5155 Score = 103 bits (246), Expect = 7e-20 Identities = 121/461 (26%), Positives = 173/461 (37%), Gaps = 43/461 (9%) Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE--VTLKVYDKPSKPEGPVIMREIS 1679 T T + I EL + I A N G + VT PS P+ V + Sbjct: 3673 TANGNTFSLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTATPATAPSAPQNLVATPQTG 3732 Query: 1680 RESVTIEWKPPLDDGGLELTKYAI-----EKHEPDNNRWIKVADVDR---DVETYCIQKL 1731 + V + W+ P +GG +T Y + E +P+N + + VD V T + L Sbjct: 3733 Q--VLLVWEKPSSNGGATITSYTVKWTPGETFDPNNFESVTITSVDGVAPPVTTTTVTGL 3790 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 Y F V A N E S P T + P D ES I W Sbjct: 3791 TNGQTYTFVVTATNSA--DEGPASNPATT-TPANPPDAPVLVSVTSDDDQEST-IVW-NQ 3845 Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT---------YQFRIYAR 1842 NGGSPIIDY VE G A I TT Y FR+ AR Sbjct: 3846 PANGGSPIIDYLVEYTSTGAFNPQDTESVVITAPQNNDPITTTIDGLDNGVEYSFRVTAR 3905 Query: 1843 NEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 N + + P + G T P PR+ V++S + V+L W P +GG + Y + Sbjct: 3906 NLVDSGDP----SNVLTGIPSTNPLPPRDLQVTDSGNAFVSLSWLTPLDDGGDDLVGYTV 3961 Query: 1903 EFK--TVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAEN-TVGVSLPTESQSVR 1958 ++ S +I+ V G + I + E FR+ A N G + T+ S Sbjct: 3962 QYSDDNFATISTQEIIPVDGVLPTTATISGLDNGSEYKFRVIAHNEDDGDNDDTDDSSDP 4021 Query: 1959 LEKHATVPSP-PTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + PS P AP LE+ G+ V SW +DGG+ L Y + D ++ E Sbjct: 4022 SNTVSATPSTVPDAPTLLEVTDHGNGFVSLSWTASVFDGGSTLNTYVVEYTDDENGVFDE 4081 Query: 2016 ------VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 +G + + + L Y R+ A N+ G S Sbjct: 4082 PPSSVIIGDDETLDTQATVSGLDNGVEYTFRVKATNDNGSS 4122 Score = 101 bits (242), Expect = 2e-19 Identities = 107/446 (23%), Positives = 187/446 (41%), Gaps = 33/446 (7%) Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPVIMRE 1677 YN T+ + + L+ K+ + A N G ++ + +V P++ P+ PVI Sbjct: 1711 YNDGQSIDTTDVPVTGLENGVLHKFRVYAVNALGNATP--SNEVEATPARAPDAPVITEL 1768 Query: 1678 ISRES-VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE--TYCIQKLNEN 1734 + + + + W P DDGG + +Y +E D + + + + TY + L Sbjct: 1769 NAGDGQIEVIWSTP-DDGGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNG 1827 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 Y FRVIA N V ES+P +++A+ V + + S+ ++W + + Sbjct: 1828 DTYYFRVIAINDVD-----ESDPSDVESAIPVTVPAKPVLNTPVVGDSSLTVSW-SAPND 1881 Query: 1795 GGSPIIDYKVEIKQE--GKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851 GGSP+ Y + I G + +L+ TY F + A N G+S P Sbjct: 1882 GGSPLTGYTLSITDVTGGNTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDP- 1940 Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 D +T G + P Q + + +ES + V L WT+P+ NG IT+Y IE + G Sbjct: 1941 --SDAVT-GIPIGAPGQIDD-LGAESGDKQVDLTWTQPDLNGSGDITSYTIEVRDSSGTL 1996 Query: 1912 WTKIVTVGGS----VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 IV G + + + F I+A N ++ T S V +T Sbjct: 1997 VDTIVITGTGGNPPATSTTVTGLTNNETYSFTITATNENNLT-STPSDPVT----STPLG 2051 Query: 1968 PPTAPLEIRMV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKVDVNTL 2024 P AP + G V +W P+ +G ++ Y + +RD + + + +G + T Sbjct: 2052 APAAPGNLTPTPGDKQVDLTWTQPDLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTT 2111 Query: 2025 KFNIRDLSENHTYMIRIYARNEIGLS 2050 + + L+ + Y + A NE L+ Sbjct: 2112 SYLVTGLTNSVNYTFEVTATNENNLT 2137 Score = 101 bits (241), Expect = 3e-19 Identities = 108/441 (24%), Positives = 176/441 (39%), Gaps = 31/441 (7%) Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREISRES-VTIEWKPPLD 1692 L + +TI A+N G +S+ +L V P P PV ++ IS + V + W P+ Sbjct: 2417 LTSGETYSFTITATNGHGLTSIP-SLPVTATPFGPPNPVTDLQAISGDKQVDLIWTQPVP 2475 Query: 1693 DGGLELTKYAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 + G + Y I +P N + I + D + + I LN EY F +IA N S Sbjct: 2476 NAGGAIETYTITVRDPSGNVVQTIVIGDDEPLATSVNIDGLNNGVEYTFEIIATN----S 2531 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ-E 1809 L+S + P D E V I W E N I Y + + Sbjct: 2532 NNLDSSAVSTTEIPFGPPGVIDTPTADAGDGE-VTIDWEEPELNDSGAIETYTITVTDPS 2590 Query: 1810 GKKWKXXXX----XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 G + + L+ Y F I A NE +L T +T +T Sbjct: 2591 GNVVQTIIIGDDEALATSTTVTGLTNGVEYSFTITATNE--NNLTSTPSTPVT-ATPITT 2647 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGG-SPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P+ P N + + + L WT P +N +T Y IE + +G++ I+ Sbjct: 2648 PNAPTNLDATALSDTEIELTWTAPPTNPQFGTLTGYQIE-RQAEGEADFTIIVADTQTTA 2706 Query: 1925 HCIENIKEKD--EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 ++ E +R+SA T G+ ++ S TVP+ P L +VG + Sbjct: 2707 TTFNDLGLSSGVEYTYRVSAITTAGIG---DASSPASATTFTVPAKPV--LNEPVVGDSS 2761 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 + SW P +GG P+ GY ++I ++T + ++ + + + L+ + Y + Sbjct: 2762 LTVSWSKPS-NGGTPITGYTLSITNLTTGIDLDDVSLSADATDYTASLLTNGNEYSFTLV 2820 Query: 2043 ARNEIGLSEPLESDEPFKVIP 2063 A N +G S ES +P IP Sbjct: 2821 AINSVGSS---ESSDPVTGIP 2838 Score = 96.3 bits (229), Expect = 8e-18 Identities = 87/347 (25%), Positives = 143/347 (41%), Gaps = 28/347 (8%) Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768 + N + V D ++ I+ L Y FR+ A+ +G+S S +V T +P Sbjct: 6489 NGNSSVTSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYS---ASSNVVTFTPATIPG 6545 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSP----IIDYKVEIKQEGKKWKXXX--XXXXX 1822 N V +T+ NGG +I Y+++ E + Sbjct: 6546 --APTPLSAQFGNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTST 6603 Query: 1823 XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 + L+ Y FR+ A NE+G S P T+ K T P P + + + ++ V Sbjct: 6604 TVTVTDLTNGEVYDFRVIAVNEVGQSDPATAS-----AKPATTPGAP-DALQLDFANQLV 6657 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI---VTVGGSVHEHCIENIKEKDEIIFR 1939 +L+W P +GG I +YI+E+ ++ W VT S + ++ + FR Sbjct: 6658 SLEWAVPTDDGGDEIDDYIVEY-SLDTSEWIVFPDNVTPANST-AVTVTDLINGFQYFFR 6715 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 IS N G+ P+E R AT+PS P LE +++ +T W PE GGAPL Sbjct: 6716 ISGVNIAGIGEPSE---FRATTPATLPSAP-RDLEATRDNTSVHLT-WNVPEDLGGAPLS 6770 Query: 2000 GYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARN 2045 Y + ++ W++ G + + L+ Y RI A+N Sbjct: 6771 AYMVEYLPPGQSTWIKFGDDLPATQTSVTVDGLTNGDQYQFRITAKN 6817 Score = 95.5 bits (227), Expect = 1e-17 Identities = 108/453 (23%), Positives = 169/453 (37%), Gaps = 36/453 (7%) Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGP 1672 EN T+ + + I L + + + A+N V TL KP+ P P Sbjct: 4181 ENTVSEVFDTEPLPTTVTIDSLTNGVTYTFRVFATNIEDNGPVSNTLDA--KPATVPTKP 4238 Query: 1673 VIMR-EISRESVTIEWKPPLDDGGLELTKYAIE---KHEPDNNRWIKVADVDRDVET--- 1725 + + E V ++W+ P D+GG E+ Y IE + W + V T Sbjct: 4239 LQLNAEFGNLLVILDWQLPADNGGEEIIDYIIEYRLASQIPEATWQVFDEGVGGVNTNLF 4298 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 + L Y FRV A+N V T D P+ I + + Sbjct: 4299 VTVTGLTNGLTYEFRVSAENAVDVGPTSNVATARPATLSDAPT----GLDAEAISDTEID 4354 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI----QKLSINTTYQFRIYA 1841 + W GG+ I Y++E + EG+ A L T+Y +R+ A Sbjct: 4355 LEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAA 4414 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 + G D T T + + V ++W+EP +NGG+PIT Y Sbjct: 4415 ITDAG-----VGDTSSTAEATTFDVPGKTEIISLTPGNAQVEVEWSEP-TNGGTPITGYR 4468 Query: 1902 IEFKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 IE+ T +T V V S I N+ D FR++A N+V P++ S Sbjct: 4469 IEYTTNETDANNGVFTSSVDVAASPLSATINNLNNGDTYYFRVTATNSVDFGEPSDVDS- 4527 Query: 1958 RLEKHATVPSPPTAPLE-IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 AT P AP + + +G V + P DGG+ ++ Y I W E Sbjct: 4528 -----ATPARAPDAPTDLVATLGDGQVTIGFTPPVEDGGSDIIDYYIEYSVDNGDNWFEF 4582 Query: 2017 G-KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + + T + + L+ Y+ R A N +G Sbjct: 4583 NDQTESTTPEITVTGLNNGQEYLFRAVAVNGVG 4615 Score = 94.7 bits (225), Expect = 2e-17 Identities = 114/453 (25%), Positives = 166/453 (36%), Gaps = 44/453 (9%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSV-EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPP 1690 I L + ++ + A N G V +V S + IS +T+ W P Sbjct: 5699 ITGLTNGQTYEFRVSAENDVGVGDVSDVATATPATASNAPTALSATAISGTEITLSWIAP 5758 Query: 1691 LDDGGLELTKYAIEKHEPDNN------RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + GG +T Y IE+H+ D N + + + D T+ L++ Y +RV A Sbjct: 5759 QNTGGFAITGYLIERHDGDGNFDDVTTLSVSLPPLPTDT-TFTDTGLSQGTTYTYRVSAV 5817 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 +G A ++ T DVP N V ++W N G+ I Y V Sbjct: 5818 TQLGPGIASGTDS---DTTFDVPDKPEITSADR--GNTQVDLSW-TEPANNGAAITAYLV 5871 Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSI-------NTTYQFRIYARNEIGTSLPYTSDDKI 1857 + +G A + +LS Y FRI A N +G S P D + Sbjct: 5872 QYSDDGTFDNTTPSVTLATADLTELSTTIDGLENGEEYSFRIIAINSVGQSDP---SDIV 5928 Query: 1858 TIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 T TP + P ++ +T VTL WT P +GGS + +Y I T+ T Sbjct: 5929 ----TATPATFPDAPTITSATFGDGQVTLTWTGPTEDGGSDVLDYTI---TITSSLGTDT 5981 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + V + I+ + F ISA N VG + ++V A P PT LE Sbjct: 5982 LVVPNTPFTRLIDGLDNGVSYTFTISARNDVGSGPDSAPETV---IPAAKPDVPT-DLEA 6037 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD-------VTKTMWMEVGKVDVNTLKFNI 2028 + + +W P GG + GY I D VT T D T Sbjct: 6038 EAISGTEIDLTWLAPVNTGGLGITGYLIERHDGDGNFATVTTTSVSVPPSTDDTTFNDTG 6097 Query: 2029 RDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 +L +TY I G S SD F V Sbjct: 6098 LELGTTYTYRISAITGAGTGSSSQPASDTTFNV 6130 Score = 94.3 bits (224), Expect = 3e-17 Identities = 110/449 (24%), Positives = 173/449 (38%), Gaps = 43/449 (9%) Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPV-IMREISRESVTIEWKPPLD 1692 L + ++ + A N+ G S L+ KP+ P P+ + E V++ W P Sbjct: 5600 LTNGQTYEFRVIAENSVGESEASNVLQA--KPATTPSKPLQVGAEFGDRQVSLTWLEPEI 5657 Query: 1693 DGGLELTKYAIE---KHEPDNNRWIKVADVDRDVET---YCIQKLNENCEYMFRVIAQNP 1746 GG ++ Y +E + W + V T I L Y FRV A+N Sbjct: 5658 SGGEDIFDYILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAEND 5717 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 VG + + TA + P+ I + ++W + GG I Y +E Sbjct: 5718 VGVGDVSDVATATPATASNAPT----ALSATAISGTEITLSWIAPQNTGGFAITGYLIER 5773 Query: 1807 KQEGKKWKXXXXXXXXXARIQK--------LSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 + + LS TTY +R+ A ++G + +D Sbjct: 5774 HDGDGNFDDVTTLSVSLPPLPTDTTFTDTGLSQGTTYTYRVSAVTQLGPGIASGTDS--- 5830 Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK---TVKGKS-WTK 1914 T P +P ++ + V L WTEP +N G+ IT Y++++ T + Sbjct: 5831 -DTTFDVPDKP-EITSADRGNTQVDLSWTEP-ANNGAAITAYLVQYSDDGTFDNTTPSVT 5887 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + T + I+ ++ +E FRI A N+VG S P++ + AT P PT + Sbjct: 5888 LATADLTELSTTIDGLENGEEYSFRIIAINSVGQSDPSD---IVTATPATFPDAPT--IT 5942 Query: 1975 IRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSEN 2034 G V +W P DGG+ +L Y I I T + V L I L Sbjct: 5943 SATFGDGQVTLTWTGPTEDGGSDVLDYTITITSSLGTDTLVVPNTPFTRL---IDGLDNG 5999 Query: 2035 HTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 +Y I ARN++G S P P VIP Sbjct: 6000 VSYTFTISARNDVG-SGP--DSAPETVIP 6025 Score = 93.1 bits (221), Expect = 8e-17 Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 48/441 (10%) Query: 1642 KYTIEASNTAGTSSVEVTLKVYDKPSK-PEGPVIMREI-SRESVTIEWKPPLDDGGLELT 1699 +YT T S + +V + P++ P+ P + + ESVT+ W P DGG +LT Sbjct: 4108 EYTFRVKATNDNGSSGYSNEVTETPARAPDAPTLDSAVRGDESVTLSWTPGF-DGGSDLT 4166 Query: 1700 KYAIEK-----HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN-----PVGF 1749 +Y ++ +P+N +V D + T I L Y FRV A N PV Sbjct: 4167 QYTVQYTPTGIFDPENT-VSEVFDTEPLPTTVTIDSLTNGVTYTFRVFATNIEDNGPV-- 4223 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809 S L+++P + T N V + W NGG IIDY +E + Sbjct: 4224 SNTLDAKPATVPT--------KPLQLNAEFGNLLVILDWQLPADNGGEEIIDYIIEYRLA 4275 Query: 1810 GK----KWK-----XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 + W+ + L+ TY+FR+ A N + P TS+ + Sbjct: 4276 SQIPEATWQVFDEGVGGVNTNLFVTVTGLTNGLTYEFRVSAENAVDVG-P-TSN--VATA 4331 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 + T P + + L+W P GG+ I Y IE + +T IV G Sbjct: 4332 RPATLSDAPTGLDAEAISDTEIDLEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTG 4391 Query: 1921 SVH-EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 S + + +R++A GV T S + + T P + G Sbjct: 4392 SADTTYSDTGLDRGTSYTYRVAAITDAGVG-DTSSTA----EATTFDVPGKTEIISLTPG 4446 Query: 1980 SNIVMTSWGTPEWDGGAPLLGYNIAI----RDVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + V W P +GG P+ GY I D ++ V + L I +L+ Sbjct: 4447 NAQVEVEWSEPT-NGGTPITGYRIEYTTNETDANNGVFTSSVDVAASPLSATINNLNNGD 4505 Query: 2036 TYMIRIYARNEIGLSEPLESD 2056 TY R+ A N + EP + D Sbjct: 4506 TYYFRVTATNSVDFGEPSDVD 4526 Score = 92.7 bits (220), Expect = 1e-16 Identities = 91/393 (23%), Positives = 146/393 (37%), Gaps = 21/393 (5%) Query: 1666 PSKPEGPVIMREI-SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 P P P + I S V I W D+ + +Y +E D W+ V + D +V Sbjct: 7709 PDPPGTPTNLSYIGSDRRVDITW----DESTGTVDRYLLEFSLNDGEEWLIVEEKDDNVP 7764 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 ++ + Y+ RV A N G S + P+ +A +P + V Sbjct: 7765 SFSKDGMVNGKVYLIRVSAANAGGISNSTSPIPV---SAFTIPGKPFDLTTQ--FGDSQV 7819 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQE-GKKWKXXXXXXXX--XARIQKLSINTTYQFRIYA 1841 + W NGG I +Y +E + G W A + L+ Y+FR+ A Sbjct: 7820 TLLWSAPVNNGGEEITNYVIEYSSDNGANWNVFDDGTSADPTATVTGLTNGQEYKFRVSA 7879 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP-ITNY 1900 N G LP K T S+P + + S+T+ W PE GG+ I+ Y Sbjct: 7880 ENIAGVGLP----SKTASDVPATQSSRPTGLSATPALD-SITITWNAPEDIGGATEISGY 7934 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 +IE G + G ++ ++ + +RI+A + P E Sbjct: 7935 VIERSISSGFFNPYVDDTGSALTSFVDTSLFSGTDYSYRIAAITLLPSGEPVVGDFSG-E 7993 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 T P P +++ +T +W PE G P+LGY I R V Sbjct: 7994 VSTTTLDLPDEPTSLQVFADRGQLTLTWIDPEDTSGLPVLGYEIERRSTGAEFTTIVENT 8053 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 D + + L++N +Y R+ G S+P Sbjct: 8054 DSDETIYTDSGLNDNTSYSYRVSTITAAGTSDP 8086 Score = 91.5 bits (217), Expect = 2e-16 Identities = 165/755 (21%), Positives = 285/755 (37%), Gaps = 64/755 (8%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDKPSP-PGKPNILEIDSS 1395 D S T+ + T+ +Y R+ N G +D T KP+ PG P+ L++D + Sbjct: 6597 DGSDTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDP---ATASAKPATTPGAPDALQLDFA 6653 Query: 1396 S--INICWDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSY 1449 + +++ W P + G I Y+VEY +DT+EWI +V T ++ +L Y Sbjct: 6654 NQLVSLEWAVPTDDGGDEIDDYIVEY-SLDTSEWIVFPDNVTPANSTAVTVTDLINGFQY 6712 Query: 1450 RFRAYAVNEVDISDASE--TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI---ELTC- 1503 FR VN I + SE T + + T + ++T ED+ L+ Sbjct: 6713 FFRISGVNIAGIGEPSEFRATTPATLPSAPRDLEATRDNTSVHLTWNVPEDLGGAPLSAY 6772 Query: 1504 IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 + +P + TW + G L + + K A D G + Sbjct: 6773 MVEYLPPGQSTWIKFGDDLPATQTSV--TVDGLTNGDQYQFRITAKNTAITDFGPASDTV 6830 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNI 1621 P I ++ W V E + YK ++ ++ Y+ Sbjct: 6831 SATPATTPTAPRDLVVIAGNNQATLSWNVP---ESNGGDSITDYKIEIRIAGQDWDVYDD 6887 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 T I I L + ++ + A N+ G +S V K P+ P+ V++ + Sbjct: 6888 GVSTTTQGIVIPNLTNGVTYEFRVTAINSVNPGPASDVVPGKPATIPTPPKKLVVIPGDT 6947 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPD-----NNRWIKVADVDRDVETYCIQKLNEN 1734 + VT W P ++GG +T Y ++ + D + + V D+ + T I L + Sbjct: 6948 KLDVT--WTKPTNNGGSAITSYLVQ-YSTDGTFDASTPSVTVTDLTNLMVT--ISGLEND 7002 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 +V A N VG S + P++ +L S I + V+++W P ++ Sbjct: 7003 VPIHVQVTAINGVGSSG--PAGPVIGVPSLG--SSSPVGLFADAISDTEVFVSWSPPQEL 7058 Query: 1795 GGSPIIDYKVE-IKQEGKKWKXXXXXXXXXARIQKLSI--NTTYQFRIYARNEI-GTSLP 1850 G + + +E + G + + TTY++++ A + G Sbjct: 7059 GDRTLEGFVLERLDANGNVLETFTINDPTKLDFTDTGLLPGTTYKYQVSALLSLEGADTV 7118 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT--VK 1908 + T TL P P + + + V L W+ P ++GGS IT Y I++ T Sbjct: 7119 QSDPSSRTSVTTLDAPGAPLSPSATPGNAH-VDLSWSAP-NDGGSLITEYRIQYSTDGTF 7176 Query: 1909 GKSWTKIVTVGGSVH----EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 ++ +I G S + + E FR+ A + SLP S +V + T Sbjct: 7177 DETTPEISVFGTSTEPPQTSVDVTGLTNDQEYTFRVIAVTVIDTSLP--SVTVTATPY-T 7233 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME----VGKVD 2020 VP P+ R G SWG P D G + Y + D T ++ V Sbjct: 7234 VPDAPSNLTANR--GPGEAKLSWGVPN-DNGRSITQYVVEYTDATDGIFTVANTLTATVS 7290 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + I L +++ R+ A N G P +S Sbjct: 7291 ASETSTTITGLGIGNSFTFRVSAENLAGQGPPSDS 7325 Score = 88.6 bits (210), Expect = 2e-15 Identities = 83/287 (28%), Positives = 119/287 (41%), Gaps = 30/287 (10%) Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKX---XXXXXXXXARIQKLSINTTYQF 1837 +E V ++W P NGGS I DY +E +G W+ + L+ +Y F Sbjct: 1292 DEQVLLSWAPPASNGGSAITDYIIEY-NDGNGWQTFNDGTSTDTTDVAVTGLTNGQSYDF 1350 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGS 1895 R+ A N GT D I T TP P V+ E+ + V L W P +NG + Sbjct: 1351 RVSAVNTEGTG------DASDIA-TATPAGVPDAPVIDEALGGNGQVYLTWEHPPNNGAA 1403 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTES 1954 IT+YIIE G W ++ G S + ++N++ + FR+ A N+ G P + Sbjct: 1404 -ITDYIIEVN--DGNGW-EVFNDGTSTNRFVTVDNLENGETYSFRVKAVNSAGEG-PFST 1458 Query: 1955 QSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 AT S TAP L G + V W P DGG+ + Y I T Sbjct: 1459 PVT-----ATPSSTATAPFLHTLTPGDSEVFVDWDAPNDDGGSTISSYEIQY-STDGTFD 1512 Query: 2014 MEVGKVDVN----TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESD 2056 V V+ ++ + L+ TY R+ A NE G S P D Sbjct: 1513 QNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRVIAINENGSSPPSNLD 1559 Score = 88.6 bits (210), Expect = 2e-15 Identities = 100/415 (24%), Positives = 159/415 (38%), Gaps = 30/415 (7%) Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKH 1706 +N T S VT P+ P + +S + + W PP + LT Y IE+ Sbjct: 2630 NNLTSTPSTPVTATPITTPNAPTN-LDATALSDTEIELTWTAPPTNPQFGTLTGYQIERQ 2688 Query: 1707 -EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 E + + I VAD T+ L+ EY +RV A G +A S P T Sbjct: 2689 AEGEADFTIIVADTQTTATTFNDLGLSSGVEYTYRVSAITTAGIGDA--SSP-ASATTFT 2745 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR 1825 VP+ + + S+ ++W NGG+PI Y + I A Sbjct: 2746 VPAKPVLNEPV--VGDSSLTVSW-SKPSNGGTPITGYTLSITNLTTGIDLDDVSLSADAT 2802 Query: 1826 IQKLSINTT---YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSV 1882 S+ T Y F + A N +G+S S D +T G L P+ P N + S + V Sbjct: 2803 DYTASLLTNGNEYSFTLVAINSVGSS---ESSDPVT-GIPLGAPAAPGNLTPT-SGDKQV 2857 Query: 1883 TLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS----VHEHCIENIKEKDEIIF 1938 L WT+P+ NG IT+Y + + G I G + + F Sbjct: 2858 DLTWTQPDLNGSGDITSYTVTVRDPNGAIVDTITLTGSQGAPPATSTTVTGLTNGVNYTF 2917 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV-GSNIVMTSWGTPEWDGGAP 1997 ++A N + P + + T P AP + G V +W P+ +G Sbjct: 2918 EVTATNENNSTGPAATTT------ETPLGAPAAPGNLTPTSGDKQVDLTWTQPDLNGSGD 2971 Query: 1998 LLGYNIAIRDVTKTM--WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 + Y I +RD + + + +G + T + + L+ + Y + A NE L+ Sbjct: 2972 ITLYTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLT 3026 Score = 87.0 bits (206), Expect = 5e-15 Identities = 109/437 (24%), Positives = 170/437 (38%), Gaps = 43/437 (9%) Query: 1669 PEGPVIMREISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK-----VADVDR 1721 P+ P ++ + V++ W + DGG L Y +E + +N + + + D Sbjct: 4033 PDAPTLLEVTDHGNGFVSLSWTASVFDGGSTLNTYVVEYTDDENGVFDEPPSSVIIGDDE 4092 Query: 1722 DVETYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 ++T + L+ EY FRV A N G S +E V +T P Sbjct: 4093 TLDTQATVSGLDNGVEYTFRVKATNDNG-SSGYSNE--VTETPARAPDAPTLDSAVRG-- 4147 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEG-------KKWKXXXXXXXXXARIQKLSINT 1833 +ESV ++W P +GGS + Y V+ G I L+ Sbjct: 4148 DESVTLSWTPGF-DGGSDLTQYTVQYTPTGIFDPENTVSEVFDTEPLPTTVTIDSLTNGV 4206 Query: 1834 TYQFRIYARN-EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 TY FR++A N E + T D K T P++P + +E + V L W P N Sbjct: 4207 TYTFRVFATNIEDNGPVSNTLD-----AKPATVPTKPLQ-LNAEFGNLLVILDWQLPADN 4260 Query: 1893 GGSPITNYIIEFK---TVKGKSWTKIVTVGGSVHEHCIENIKEKDEII---FRISAENTV 1946 GG I +YIIE++ + +W G V+ + + + FR+SAEN V Sbjct: 4261 GGEEIIDYIIEYRLASQIPEATWQVFDEGVGGVNTNLFVTVTGLTNGLTYEFRVSAENAV 4320 Query: 1947 GVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 V PT +V + AT+ PT L+ + + W P GGA + GY I R Sbjct: 4321 DVG-PT--SNVATARPATLSDAPTG-LDAEAISDTEIDLEWNAPLLTGGASIDGYQIE-R 4375 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRD--LSENHTYMIRIYARNEIGLSEPLESDEPFKV-IP 2063 + D + D L +Y R+ A + G+ + + E +P Sbjct: 4376 QAEGEADFTIIVADTGSADTTYSDTGLDRGTSYTYRVAAITDAGVGDTSSTAEATTFDVP 4435 Query: 2064 GEGSHADEEPGE-QTEV 2079 G+ PG Q EV Sbjct: 4436 GKTEIISLTPGNAQVEV 4452 Score = 86.6 bits (205), Expect = 7e-15 Identities = 115/467 (24%), Positives = 179/467 (38%), Gaps = 55/467 (11%) Query: 1635 LKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 L+ ++ + A +T GTS S T PS P V R + S+T W P D Sbjct: 6195 LENGEEYEFRVYAISTVGTSLPSDVATGIPATTPSAPLNVVATRGDTEVSLT--WDLPAD 6252 Query: 1693 DGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFS 1750 DGG + Y +E + N + + + + + + L EY FRV A N + Sbjct: 6253 DGGSAIRDYLVEYASAELNLIYTPFVEPEESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG 6312 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 + S A+ D+E V +TW S+ NGG+ ++ Y++E +G Sbjct: 6313 DY--SAVTADSAAVPAGDPSTPVISTVIADDELVNLTWLASDANGGNNLV-YRIETSTDG 6369 Query: 1811 KKWKXXX---XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 + L Y FRI A + G+S P T T TP + Sbjct: 6370 FTTLIEDPAPTTSNLVYNVDDLQNGQEYSFRITAITDAGSSDP-------TAPVTATPFA 6422 Query: 1868 QPRNFVVSESTSRS-VTLKWTEPESNGGSPITNYII-----EFKTV-------------- 1907 P V+ S + VTL WT+ ++ GG I ++I EF + Sbjct: 6423 LPDAPVLDGSRGNTEVTLTWTQGDT-GGFAIQEFVIEYTADEFTSDTPIVRTNDDDDDDD 6481 Query: 1908 -------KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 G S +TV H IE + FRI A+ ++G S S +V Sbjct: 6482 DDDDDDGNGNSSVTSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYSA---SSNVVTF 6538 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK---TMWMEVG 2017 AT+P PT PL + G+ +V ++ P +GG + + I R + T + Sbjct: 6539 TPATIPGAPT-PLSAQF-GNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFA 6596 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064 + + DL+ Y R+ A NE+G S+P + PG Sbjct: 6597 DGSDTSTTVTVTDLTNGEVYDFRVIAVNEVGQSDPATASAKPATTPG 6643 Score = 85.4 bits (202), Expect = 2e-14 Identities = 101/421 (23%), Positives = 157/421 (37%), Gaps = 30/421 (7%) Query: 1643 YTIEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 YT E S T +S T Y P+ P + + V + W P +G ++ Sbjct: 3113 YTFEVSATNENNSTGPAATATATPYGPPAAPGN--LTPTPGDKQVDLTWTQPDLNGSGDI 3170 Query: 1699 TKYAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 T Y I +P + I + D + +Y + L + Y F V A N + + + Sbjct: 3171 TLYTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLTSSAATT 3230 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKX 1815 TA + + ++W ++ N I Y + I +G Sbjct: 3231 -----TATPRGAPLQVTGLEATPGDRQASLSWNEADDNNSGDISYYTITITGSDGVPVDP 3285 Query: 1816 XXXXX-XXXARIQKLSINTTYQFRIYARNEIG-TSLPYTSDDKITIGKTLTPPSQPRNFV 1873 I L+ Y+F I A NE G TS P G PP+ Sbjct: 3286 VQVTAPADNTVIPGLTSGVEYEFTITATNEHGLTSTPSAPATATPFG----PPNAVTGLG 3341 Query: 1874 VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEK 1933 + + V L+WTEP N G I +Y I G + + +T+ E I+ + Sbjct: 3342 ATPG-DKQVDLEWTEPVPNAGGEIASYTITVTDPNG-NVVQTITINAPADEANIDGLNNG 3399 Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 E F I+A N GV T + ATVP PP L+ G+ V SW TP++D Sbjct: 3400 VEYTFTITATNVNGV---TGDAATITAIPATVPLPPV--LDSADRGNQSVTLSW-TPQFD 3453 Query: 1994 GGAPLLGYNI--AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 G+ + Y I + + T + +G + I L+ TY ++ A N G S+ Sbjct: 3454 QGSTITQYTIQYSSDNFQTTGTVVIGDDEALATSTTISGLTNGLTYQFQVIASNAFGPSD 3513 Query: 2052 P 2052 P Sbjct: 3514 P 3514 Score = 77.4 bits (182), Expect = 4e-12 Identities = 138/691 (19%), Positives = 249/691 (36%), Gaps = 56/691 (8%) Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV---KNITKTQTSIQNLKTN 1446 +E + + W P N G I YV+E D ++ ++I T + L+ Sbjct: 1672 VERGDEQVLLTWSAPNNHG-FPITDYVIEVDYGDGNGFVVYNDGQSIDTTDVPVTGLENG 1730 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL---TC 1503 ++FR YAVN + +A+ + E ++ T ++P + P+ + IE+ T Sbjct: 1731 VLHKFRVYAVNA--LGNATPSNE----VEATPARAP--DAPVITELNAGDGQIEVIWSTP 1782 Query: 1504 IFGG--VPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGE 1558 GG + + ++ W + T ++ IA ND E Sbjct: 1783 DDGGESIDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTYYFRVIAINDVDE 1842 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV---TAVIEGIPPPEVIWYKNGNKLEN 1615 + S ++ +T+ + + VGD L +A +G P + Sbjct: 1843 SDPS---DVESAIPVTVPAKPVLNTPVVGDSSLTVSWSAPNDGGSPLTGYTLSITDVTGG 1899 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 + +++ EL ++ +T+ A N G+S + + + + Sbjct: 1900 NTFPDVSLPANAIDYNASELTNGNTYSFTLIAINAEGSSDPSDAVTGIPIGAPGQIDDLG 1959 Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV----DRDVETYCIQKL 1731 E + V + W P +G ++T Y IE + + + + + L Sbjct: 1960 AESGDKQVDLTWTQPDLNGSGDITSYTIEVRDSSGTLVDTIVITGTGGNPPATSTTVTGL 2019 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 N Y F + A N + S+P+ T L P+ ++ V +TW Sbjct: 2020 TNNETYSFTITATNENNLTST-PSDPVT-STPLGAPAAPGNLTPTPG--DKQVDLTWTQP 2075 Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXAR-----IQKLSINTTYQFRIYARNEIG 1846 + NG II Y V ++ A + L+ + Y F + A NE Sbjct: 2076 DLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENN 2135 Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 TS T L P Q + +ES + V L WT+P+ NG IT+Y IE + Sbjct: 2136 L----TSSAATTTSTPLGAPGQI-DTPTAESGDKQVDLTWTQPDLNGSGDITSYTIEVRD 2190 Query: 1907 VKGKSWTKIVTVGGS----VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 G IV G + + + + F I+A N ++ T S V Sbjct: 2191 SSGTLVDTIVITGTGGNPPATSYTVPGLDNGETYSFTITATNENNLT-STPSDPVT---- 2245 Query: 1963 ATVPSPPTAPLEIRMV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKV 2019 +T P AP + G V +W P+ + + Y I +RD + + + +G Sbjct: 2246 STPLGAPAAPGNLAPTPGDKQVDLTWTQPDLNNSGDITLYTITVRDPSGAVVQTIVIGDD 2305 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 + + + L+ + Y + A NE L+ Sbjct: 2306 EALATETTVTGLTNSVNYTFEVTATNENNLT 2336 Score = 73.7 bits (173), Expect = 5e-11 Identities = 92/365 (25%), Positives = 139/365 (38%), Gaps = 30/365 (8%) Query: 1643 YTIEASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 Y I A AGT SS + ++ P KP + + + I W P D+GG +T Sbjct: 6106 YRISAITGAGTGSSSQPASDTTFNVPDKPT--ITEVNVGNNELEIVWTAPTDNGGSPVTS 6163 Query: 1701 YAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y +E +N W V D ++ I L EY FRV A + VG S P Sbjct: 6164 YTVEYKLTTDNTWQLSPVPPADGALDVTVI-GLENGEEYEFRVYAISTVG-----TSLPS 6217 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-----KKW 1813 + T + + + V +TW +GGS I DY VE + Sbjct: 6218 DVATGIPATTPSAPLNVVATRGDTEVSLTWDLPADDGGSAIRDYLVEYASAELNLIYTPF 6277 Query: 1814 KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV 1873 + L+ Y FR+ A NEI Y++ +T P P V Sbjct: 6278 VEPEESTDRFTTVTGLTNGVEYTFRVQAVNEIAAG-DYSA---VTADSAAVPAGDPSTPV 6333 Query: 1874 VSE--STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 +S + V L W ++NGG+ + Y IE T + + S + +++++ Sbjct: 6334 ISTVIADDELVNLTWLASDANGGNNLV-YRIETSTDGFTTLIEDPAPTTSNLVYNVDDLQ 6392 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 E FRI+A G S PT + AT + P AP+ G+ V +W + Sbjct: 6393 NGQEYSFRITAITDAGSSDPTAPVT------ATPFALPDAPVLDGSRGNTEVTLTWTQGD 6446 Query: 1992 WDGGA 1996 G A Sbjct: 6447 TGGFA 6451 Score = 70.5 bits (165), Expect = 5e-10 Identities = 106/461 (22%), Positives = 170/461 (36%), Gaps = 55/461 (11%) Query: 1609 NGNKLENDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTS-SVEVTLKVYDK 1665 NGN LE + T + T ++ K S+ ++E ++T + S ++ D Sbjct: 7074 NGNVLETFTINDPTKLDFTDTGLLPGTTYKYQVSALLSLEGADTVQSDPSSRTSVTTLDA 7133 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP----DNNRWIKV--ADV 1719 P P P V + W P +DGG +T+Y I+ + I V Sbjct: 7134 PGAPLSPSATP--GNAHVDLSWSAP-NDGGSLITEYRIQYSTDGTFDETTPEISVFGTST 7190 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXI 1779 + + + L + EY FRVIA + S + T D PS Sbjct: 7191 EPPQTSVDVTGLTNDQEYTFRVIAVTVIDTSLPSVTVTATPYTVPDAPSNLTANRGPG-- 7248 Query: 1780 DNESVYITWFPSEKNGGSPIIDYKVE-------IKQEGKKWKXXXXXXXXXARIQKLSIN 1832 ++W NG S I Y VE I I L I Sbjct: 7249 ---EAKLSWGVPNDNGRS-ITQYVVEYTDATDGIFTVANTLTATVSASETSTTITGLGIG 7304 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 ++ FR+ A N G P S I T P P + + + W P S+ Sbjct: 7305 NSFTFRVSAENLAGQGPPSDS----AIATPATAPDAPTGLSATRGDPDVLAI-WFNPPSD 7359 Query: 1893 GGSPITNYIIEFKT---------VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 GGSPI++Y++E+ T S T ++T SV +++++ FR+ A Sbjct: 7360 GGSPISHYVLEYTTSPFFVPPEIADFTSKTNVITESTSVE---LDDLENGLYYYFRVRAI 7416 Query: 1944 NTVGVSLPTE---------SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS---WGTPE 1991 TVG S+PT+ S S A +P + ++G+ + W TP Sbjct: 7417 TTVGSSIPTDPVCLVNGGGSNSAANAGGACIPMFDRPVFQDTIIGTPFDAAAELRWNTPA 7476 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 D G+P+ GY + R V + + + + N + + DL+ Sbjct: 7477 ADNGSPITGYQVQ-RQVVSGTSVVLEQFNQNQIIYGFDDLT 7516 Score = 69.3 bits (162), Expect = 1e-09 Identities = 57/233 (24%), Positives = 96/233 (41%), Gaps = 15/233 (6%) Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 I+ L+ Y FRI+A+ IG Y++ + T P P + ++ + VTL Sbjct: 6508 IEGLANGVAYDFRIFAKTSIG----YSASSNVVTFTPATIPGAPTP-LSAQFGNALVTLT 6562 Query: 1886 WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH---CIENIKEKDEIIFRISA 1942 ++ P NGG + +++I+++ T T + ++ + FR+ A Sbjct: 6563 FSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTSTTVTVTDLTNGEVYDFRVIA 6622 Query: 1943 ENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYN 2002 N VG S P + + K AT P P A L++ + +V W P DGG + Y Sbjct: 6623 VNEVGQSDPATASA----KPATTPGAPDA-LQLDF-ANQLVSLEWAVPTDDGGDEIDDYI 6676 Query: 2003 IAIR-DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + D ++ + N+ + DL Y RI N G+ EP E Sbjct: 6677 VEYSLDTSEWIVFPDNVTPANSTAVTVTDLINGFQYFFRISGVNIAGIGEPSE 6729 Score = 68.5 bits (160), Expect = 2e-09 Identities = 49/178 (27%), Positives = 77/178 (43%), Gaps = 9/178 (5%) Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXX---XXXXARIQKLSINTTYQ 1836 +E V ++W +GG+ I Y V+ + G W + L TY+ Sbjct: 342 DEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTTSLPVTGLINGVTYE 401 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 F++ A N +G S P + T ++T P QP S + ++ V L WT P S+GGS Sbjct: 402 FQVLAHNSVGNSNP-SGAANATPEDSVTVPGQPTELTAS-AGNQQVLLSWTAP-SDGGSA 458 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 IT+YI+E G W + + + + E FR+SA N G +E+ Sbjct: 459 ITDYIVEVD--DGDGWETFADGTSTDTTATVTGLTNEQEHTFRVSAVNDEGTGNTSET 514 Score = 67.7 bits (158), Expect = 3e-09 Identities = 58/194 (29%), Positives = 82/194 (42%), Gaps = 14/194 (7%) Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKI 1915 IT L P P N + +ES V L W P SNGGS IT+YIIE+ G W T Sbjct: 1271 ITYTAELGVPGAPTN-LTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFN 1327 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + + + FR+SA NT G ++ + A VP P ++ Sbjct: 1328 DGTSTDTTDVAVTGLTNGQSYDFRVSAVNTEGTG---DASDIATATPAGVPDAPV--IDE 1382 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF-NIRDLSEN 2034 + G+ V +W P + GA + Y I + D W EV +T +F + +L Sbjct: 1383 ALGGNGQVYLTWEHPP-NNGAAITDYIIEVND--GNGW-EVFNDGTSTNRFVTVDNLENG 1438 Query: 2035 HTYMIRIYARNEIG 2048 TY R+ A N G Sbjct: 1439 ETYSFRVKAVNSAG 1452 Score = 67.3 bits (157), Expect = 4e-09 Identities = 49/195 (25%), Positives = 82/195 (42%), Gaps = 7/195 (3%) Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGG 1920 T + P QP N + + + VT+ WT P S+GG+ I Y ++++ +WT T G Sbjct: 326 TASVPGQPLN-ISATAGDEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDG 384 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + + F++ A N+VG S P+ + + E TVP PT G+ Sbjct: 385 TTTSLPVTGLINGVTYEFQVLAHNSVGNSNPSGAANATPEDSVTVPGQPTE--LTASAGN 442 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 V+ SW P DGG+ + Y + + D W + L+ + R Sbjct: 443 QQVLLSWTAPS-DGGSAITDYIVEVDD--GDGWETFADGTSTDTTATVTGLTNEQEHTFR 499 Query: 2041 IYARNEIGLSEPLES 2055 + A N+ G E+ Sbjct: 500 VSAVNDEGTGNTSET 514 Score = 66.9 bits (156), Expect = 6e-09 Identities = 92/428 (21%), Positives = 152/428 (35%), Gaps = 43/428 (10%) Query: 1643 YTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREISRES-VTIEWKPPLDDGGLELTK 1700 YT E + T +S + P P P + S + V + W P +G ++T Sbjct: 2915 YTFEVTATNENNSTGPAATTTETPLGAPAAPGNLTPTSGDKQVDLTWTQPDLNGSGDITL 2974 Query: 1701 YAIEKHEPDNN--RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y I +P + I + D + +Y + L + Y F V A N + + + Sbjct: 2975 YTITVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVTATNENNLTSSAATT-- 3032 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXX 1818 TA + ++ V + W P+++N I Y VE+ Sbjct: 3033 ---TATPRGAPLQVTGLEATPGDKQVSLEWDPADENNSGAITSYTVEVYDSSNTLVDTIT 3089 Query: 1819 XX-------XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + L TY F + A NE ++ P + G PP+ P N Sbjct: 3090 VTGTGGNPPATSTTVTGLDNGETYTFEVSATNENNSTGPAATATATPYG----PPAAPGN 3145 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS---VHEHCIE 1928 + + V L WT+P+ NG IT Y I + G + + + +G + + Sbjct: 3146 LTPTPG-DKQVDLTWTQPDLNGSGDITLYTITVRDPSG-AVVQTIVIGDDEALTTSYLVT 3203 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV----GSNIVM 1984 + F ++A N + T S + T +P APL++ + G Sbjct: 3204 GLTNSVNYTFEVTATNENNL---TSSAA------TTTATPRGAPLQVTGLEATPGDRQAS 3254 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFN--IRDLSENHTYMIRIY 2042 SW + + + Y I I T + + V V V N I L+ Y I Sbjct: 3255 LSWNEADDNNSGDISYYTITI---TGSDGVPVDPVQVTAPADNTVIPGLTSGVEYEFTIT 3311 Query: 2043 ARNEIGLS 2050 A NE GL+ Sbjct: 3312 ATNEHGLT 3319 Score = 60.1 bits (139), Expect = 7e-07 Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 7/170 (4%) Query: 1681 ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMF 1739 E VT+ W P DGG + Y ++ W + D + + L Y F Sbjct: 343 EQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTTSLPVTGLINGVTYEF 402 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 +V+A N VG S + + ++ VP N+ V ++W + +GGS I Sbjct: 403 QVLAHNSVGNSNPSGAANATPEDSVTVPGQPTELTASA--GNQQVLLSW-TAPSDGGSAI 459 Query: 1800 IDYKVEIKQEGKKWKXXX--XXXXXXARIQKLSINTTYQFRIYARNEIGT 1847 DY VE+ +G W+ A + L+ + FR+ A N+ GT Sbjct: 460 TDYIVEV-DDGDGWETFADGTSTDTTATVTGLTNEQEHTFRVSAVNDEGT 508 Score = 58.8 bits (136), Expect = 2e-06 Identities = 104/468 (22%), Positives = 170/468 (36%), Gaps = 49/468 (10%) Query: 1638 SHSSKYTIEAS----NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 ++S YT E + N +S+ T P + + P E + V + W P + Sbjct: 2119 TNSVNYTFEVTATNENNLTSSAATTTSTPLGAPGQIDTPTA--ESGDKQVDLTWTQPDLN 2176 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADV----DRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 G ++T Y IE + + + +Y + L+ Y F + A N Sbjct: 2177 GSGDITSYTIEVRDSSGTLVDTIVITGTGGNPPATSYTVPGLDNGETYSFTITATNENNL 2236 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQE 1809 + S+P+ T L P+ ++ V +TW + N I Y + ++ Sbjct: 2237 TST-PSDPVT-STPLGAPAAPGNLAPTPG--DKQVDLTWTQPDLNNSGDITLYTITVRDP 2292 Query: 1810 GKKWKXXXXXXXXXA-----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864 A + L+ + Y F + A NE TS T T T Sbjct: 2293 SGAVVQTIVIGDDEALATETTVTGLTNSVNYTFEVTATNENNL----TSSAATT---TAT 2345 Query: 1865 PPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS- 1921 P P E+T R V+L+W + N IT+Y +E + +TV G+ Sbjct: 2346 PRGAPEQVTGLEATPGDRQVSLEWDPADENNSGAITSYTVEVYD-SSNTLVDTITVTGTG 2404 Query: 1922 ----VHEHCIENIKEKDEIIFRISAENTVGV-SLPTESQSVRLEKHATVPSPPTAPLEIR 1976 + + + F I+A N G+ S+P+ L AT PP +++ Sbjct: 2405 GNPPATSTTVPGLTSGETYSFTITATNGHGLTSIPS------LPVTATPFGPPNPVTDLQ 2458 Query: 1977 MV-GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM--WMEVGKVDVNTLKFNIRDLSE 2033 + G V W P + G + Y I +RD + + + +G + NI L+ Sbjct: 2459 AISGDKQVDLIWTQPVPNAGGAIETYTITVRDPSGNVVQTIVIGDDEPLATSVNIDGLNN 2518 Query: 2034 NHTYMIRIYARNEIGL-SEPLESDE-PFKVIPG--EGSHADEEPGEQT 2077 Y I A N L S + + E PF PG + AD GE T Sbjct: 2519 GVEYTFEIIATNSNNLDSSAVSTTEIPFGP-PGVIDTPTADAGDGEVT 2565 Score = 53.2 bits (122), Expect = 8e-05 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 15/184 (8%) Query: 1585 KVGDEWLVTAVIEGIPPPEVI--WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH--- 1639 K+ +W+ G P + W NG N T K S + +K S+ Sbjct: 8595 KIVIDWVAPTSNGGTPIVNYLIQWSDNGGSKWN------TLKRDASAVTSATVKSSNIVL 8648 Query: 1640 SSKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGP-VIMREISRESVTIEWKPPLDDGGL 1696 ++Y I A NT G ++K + P P ++ + V + W PL DGG Sbjct: 8649 GTEYQIRVYAENTIGPGPAS-SVKSVTPTTIPTAPRSLVTDPQDGQVVLSWSKPLSDGGS 8707 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +T Y + E + +++ AD T + L + Y FRV+A N VG S A + Sbjct: 8708 AITDYLVRYSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRVVAVNSVGNSPASTGK 8767 Query: 1757 PIVI 1760 + + Sbjct: 8768 SVAV 8771 Score = 51.2 bits (117), Expect = 3e-04 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 11/137 (8%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN---ILEIDSSSINIC 1400 S+TI + N +++ +N + NV + S P P + I ++I Sbjct: 5285 SITIDDLTNGVTYEFRVFAKNTVPGQSLPSNVLSAEPSSAPSVPRDLRVTNIGDEFVSIS 5344 Query: 1401 WDEPENTGNSTIIYYVVEYQE-----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 W P + G I+ Y V+Y + I T E + V + T ++ +L+ Y+FR A Sbjct: 5345 WLAPADNGGDDIVGYTVQYSDDNFTTISTQEIVPVSGVLPTDATVSSLENGVDYQFRVIA 5404 Query: 1456 VNEVD---ISDASETTE 1469 NE D I D+S+ ++ Sbjct: 5405 HNEDDDPQIPDSSDPSD 5421 Score = 51.2 bits (117), Expect = 3e-04 Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 13/156 (8%) Query: 1346 TIKKVENTDAGIYKLRLEN--NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 T +EN Y++ N G A + T LD P PP ++ + + WD Sbjct: 8337 TDNSLENGQTYYYRISAINAKGTGTASDVASATPLDVPGPPRNLQTTP-GNAQVTLAWDI 8395 Query: 1404 PE-------NTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAY 1454 P + G S I YVV Y IDT W + + IT+ + L +Y+FR + Sbjct: 8396 PSTDGGITADNGGSIITGYVVHYA-IDTNFWKTFNEEPITERTVDVTGLTNGQNYKFRVF 8454 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 AVNEV S + V + T+ P +N Sbjct: 8455 AVNEVGFLHPSLVSSEIPVTVPERPWGLTITAPSQN 8490 Score = 49.6 bits (113), Expect = 0.001 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 9/91 (9%) Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTE------WISVKNITK 1435 P KP I D ++ +++ W EP N G + I Y+V+Y + T + ++ ++T+ Sbjct: 5837 PDKPEITSADRGNTQVDLSWTEPANNG-AAITAYLVQYSDDGTFDNTTPSVTLATADLTE 5895 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 T+I L+ Y FR A+N V SD S+ Sbjct: 5896 LSTTIDGLENGEEYSFRIIAINSVGQSDPSD 5926 Score = 48.8 bits (111), Expect = 0.002 Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 +T + PS P N + + + V+L WT P NGGS IT+Y++E+ + G W Sbjct: 983 VTYSFEASAPSAPTNLIATAGNT-DVSLSWTAP-FNGGSDITDYVVEYSS--GSGWNTFA 1038 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 + + + E FR+SA N G Sbjct: 1039 DGTSTDTTATVTGLTNDQEYSFRVSAVNAEG 1069 Score = 47.6 bits (108), Expect = 0.004 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 10/114 (8%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE-----IDTTEWISVKNITK 1435 P PP + + ++ +++ W P + G ++ Y V+Y + I T E I V + Sbjct: 3925 PLPPRDLQVTDSGNAFVSLSWLTPLDDGGDDLVGYTVQYSDDNFATISTQEIIPVDGVLP 3984 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNE-----VDISDASETTEYYKVIKETKIQSPTV 1484 T +I L S Y+FR A NE D D+S+ + T +PT+ Sbjct: 3985 TTATISGLDNGSEYKFRVIAHNEDDGDNDDTDDSSDPSNTVSATPSTVPDAPTL 4038 Score = 47.2 bits (107), Expect = 0.005 Identities = 34/133 (25%), Positives = 59/133 (44%), Gaps = 5/133 (3%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSS 1396 D + SL + + N +++ N+ G+++ N T D + PG+P L + + Sbjct: 383 DGTTTSLPVTGLINGVTYEFQVLAHNSVGNSNPSGAANATPEDSVTVPGQPTELTASAGN 442 Query: 1397 --INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + W P + G S I Y+VE + D E + T T ++ L + FR Sbjct: 443 QQVLLSWTAPSD-GGSAITDYIVEVDDGDGWETFADGTSTDTTATVTGLTNEQEHTFRVS 501 Query: 1455 AVNEVDISDASET 1467 AVN+ + SET Sbjct: 502 AVNDEGTGNTSET 514 Score = 46.8 bits (106), Expect = 0.007 Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 7/132 (5%) Query: 1340 SKSASLTIKKVENTDAGIYKLRL--ENNCGH--ADVEMNVTILDKPSPPGKPNILEIDSS 1395 S S T+K Y++R+ EN G A +VT P+ P + + + Sbjct: 8634 SAVTSATVKSSNIVLGTEYQIRVYAENTIGPGPASSVKSVTPTTIPTAP-RSLVTDPQDG 8692 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRA 1453 + + W +P + G S I Y+V Y E + ++++ + T T ++ L + +Y FR Sbjct: 8693 QVVLSWSKPLSDGGSAITDYLVRYSEAGSGQFVTFADGVSTSTTATVTGLTNDVTYEFRV 8752 Query: 1454 YAVNEVDISDAS 1465 AVN V S AS Sbjct: 8753 VAVNSVGNSPAS 8764 Score = 46.4 bits (105), Expect = 0.009 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 1384 PGKPNILEIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT--- 1438 PG P L +S + + W P + G S I Y++EY D W + + T T T Sbjct: 1280 PGAPTNLTAESGDEQVLLSWAPPASNGGSAITDYIIEYN--DGNGWQTFNDGTSTDTTDV 1337 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASE 1466 ++ L SY FR AVN DAS+ Sbjct: 1338 AVTGLTNGQSYDFRVSAVNTEGTGDASD 1365 Score = 46.4 bits (105), Expect = 0.009 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 15/125 (12%) Query: 1384 PGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT----Q 1437 P KP I E++ ++ + I W P + G S + Y VEY+ W + + Sbjct: 6131 PDKPTITEVNVGNNELEIVWTAPTDNGGSPVTSYTVEYKLTTDNTW-QLSPVPPADGALD 6189 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 ++ L+ Y FR YA++ V S S+ T I + T PL + T + Sbjct: 6190 VTVIGLENGEEYEFRVYAISTVGTSLPSDVA--------TGIPATTPSAPLNVVATRGDT 6241 Query: 1498 DIELT 1502 ++ LT Sbjct: 6242 EVSLT 6246 Score = 46.0 bits (104), Expect = 0.011 Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 11/133 (8%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWD 1402 SL I ++ N ++++ N+ G D+ VT +P N++ + + + W+ Sbjct: 3680 SLVIDELTNGTPYLFEIFAHNDVGDGDISDRVTATPATAPSAPQNLVATPQTGQVLLVWE 3739 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----------KTQTSIQNLKTNSSYRFR 1452 +P + G +TI Y V++ +T + + +++T T T++ L +Y F Sbjct: 3740 KPSSNGGATITSYTVKWTPGETFDPNNFESVTITSVDGVAPPVTTTTVTGLTNGQTYTFV 3799 Query: 1453 AYAVNEVDISDAS 1465 A N D AS Sbjct: 3800 VTATNSADEGPAS 3812 Score = 45.6 bits (103), Expect = 0.015 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 6/125 (4%) Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSIN 1398 S + +T+ +EN + ++++ N+ G VT + + L S + Sbjct: 1425 STNRFVTVDNLENGETYSFRVKAVNSAGEGPFSTPVTATPSSTATAPFLHTLTPGDSEVF 1484 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDT----TEWISVK-NITKTQTSIQNLKTNSSYRFRA 1453 + WD P + G STI Y ++Y T T ++V N T+ ++ L +Y FR Sbjct: 1485 VDWDAPNDDGGSTISSYEIQYSTDGTFDQNTPSVTVSGNPPLTEYTVPGLTNGQTYTFRV 1544 Query: 1454 YAVNE 1458 A+NE Sbjct: 1545 IAINE 1549 Score = 45.2 bits (102), Expect = 0.020 Identities = 31/129 (24%), Positives = 57/129 (44%), Gaps = 5/129 (3%) Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWDE 1403 +T+ +EN + +++ + G + T + +P N++ + +++ WD Sbjct: 6190 VTVIGLENGEEYEFRVYAISTVGTSLPSDVATGIPATTPSAPLNVVATRGDTEVSLTWDL 6249 Query: 1404 PENTGNSTIIYYVVEYQEIDT----TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 P + G S I Y+VEY + T ++ + T T++ L Y FR AVNE+ Sbjct: 6250 PADDGGSAIRDYLVEYASAELNLIYTPFVEPEESTDRFTTVTGLTNGVEYTFRVQAVNEI 6309 Query: 1460 DISDASETT 1468 D S T Sbjct: 6310 AAGDYSAVT 6318 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 +T T PS P N + + V+L WT P S+GGS IT+YIIE G W Sbjct: 696 VTYSFVATAPSAPTNLSATAGNEQ-VSLSWTAP-SDGGSAITDYIIEVD--DGDGWETFA 751 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 + + + E FR+SA N G Sbjct: 752 DGTSTDTTATVTGLTNGQEHTFRVSAVNGEG 782 Score = 44.0 bits (99), Expect = 0.046 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 6/90 (6%) Query: 1382 SPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITK 1435 S PG P LE + I I W P + G + I+ Y++++ + ++W ++K +T Sbjct: 8579 SVPGAPRNLTLEAEGKKIVIDWVAPTSNGGTPIVNYLIQWSDNGGSKWNTLKRDASAVTS 8638 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 N+ + Y+ R YA N + AS Sbjct: 8639 ATVKSSNIVLGTEYQIRVYAENTIGPGPAS 8668 Score = 43.2 bits (97), Expect = 0.081 Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 13/126 (10%) Query: 1353 TDAGIYKLRL--ENNCGHADVEMNVTILDKPSPPGKPNIL--EIDSSSINICWDEPENTG 1408 T+ Y+ R+ EN+ G ++ NV + P KP + E +++ W EPE +G Sbjct: 5601 TNGQTYEFRVIAENSVGESEAS-NVLQAKPATTPSKPLQVGAEFGDRQVSLTWLEPEISG 5659 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKNI--------TKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 I Y++E++ T S + T I L +Y FR A N+V Sbjct: 5660 GEDIFDYILEFRLASQTPEASWQTFDEGLGGVNTNLSAIITGLTNGQTYEFRVSAENDVG 5719 Query: 1461 ISDASE 1466 + D S+ Sbjct: 5720 VGDVSD 5725 Score = 42.3 bits (95), Expect = 0.14 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 9/136 (6%) Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNC----GHADVEMNVTILDKPSPPGKPNILEID 1393 + + S+T+ + N D +++ +N G A ++ T P+ P + ++ Sbjct: 6791 LPATQTSVTVDGLTNGDQYQFRITAKNTAITDFGPASDTVSATPATTPTAP-RDLVVIAG 6849 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYR 1450 ++ + W+ PE+ G +I Y +E + I +W + T T I NL +Y Sbjct: 6850 NNQATLSWNVPESNGGDSITDYKIEIR-IAGQDWDVYDDGVSTTTQGIVIPNLTNGVTYE 6908 Query: 1451 FRAYAVNEVDISDASE 1466 FR A+N V+ AS+ Sbjct: 6909 FRVTAINSVNPGPASD 6924 Score = 41.9 bits (94), Expect = 0.19 Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 9/107 (8%) Query: 1367 GHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY------- 1419 G A T + P P ++ D I W++P N G S II Y+VEY Sbjct: 3809 GPASNPATTTPANPPDAPVLVSVTSDDDQESTIVWNQPAN-GGSPIIDYLVEYTSTGAFN 3867 Query: 1420 -QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 Q+ ++ + +N T+I L Y FR A N VD D S Sbjct: 3868 PQDTESVVITAPQNNDPITTTIDGLDNGVEYSFRVTARNLVDSGDPS 3914 Score = 41.5 bits (93), Expect = 0.25 Identities = 31/137 (22%), Positives = 62/137 (45%), Gaps = 8/137 (5%) Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL--E 1391 T ++ + + S TI+ + N A +++ + + G++ NV + PG P L + Sbjct: 6495 TSITVSADAVSHTIEGLANGVAYDFRIFAKTSIGYS-ASSNVVTFTPATIPGAPTPLSAQ 6553 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI-----TKTQTSIQNLKTN 1446 ++ + + + P + G ++ +V++Y+ +E T T ++ +L Sbjct: 6554 FGNALVTLTFSIPSDNGGESVDDFVIQYRLQSASEDTPFTTFADGSDTSTTVTVTDLTNG 6613 Query: 1447 SSYRFRAYAVNEVDISD 1463 Y FR AVNEV SD Sbjct: 6614 EVYDFRVIAVNEVGQSD 6630 Score = 40.3 bits (90), Expect = 0.57 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 5/89 (5%) Query: 1382 SPPGKP-NI-LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI---TKT 1436 S PG+P NI + + W P + G + I YY V+Y+ W N T T Sbjct: 328 SVPGQPLNISATAGDEQVTVSWTAPNSDGGAAIDYYTVQYRVSGIPAWTDFGNTPDGTTT 387 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + L +Y F+ A N V S+ S Sbjct: 388 SLPVTGLINGVTYEFQVLAHNSVGNSNPS 416 Score = 39.9 bits (89), Expect = 0.75 Identities = 80/416 (19%), Positives = 144/416 (34%), Gaps = 35/416 (8%) Query: 1648 SNTAGTSSVEVTLKVYD-KPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 S+ +S+ + + Y + S P P ++ V++ W P + GG ++T Y +E Sbjct: 970 SHDGDSSAAPLLVVTYSFEASAPSAPTNLIATAGNTDVSLSWTAPFN-GGSDITDYVVEY 1028 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESEPI-VIK 1761 + W AD T + L + EY FRV A N G S + PI + Sbjct: 1029 SS--GSGWNTFADGTSTDTTATVTGLTNDQEYSFRVSAVNAEGTGPVSNIATATPIGALT 1086 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821 + + +D + + +GG + Y +++ + Sbjct: 1087 ITIQISQSSDDAEQIRTVDEDD-------DDDDGGGGGVSYSMDLDDDDLDLDEDRFVGL 1139 Query: 1822 XXARI---QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + +I Y N+ G+S + + T T S + S S Sbjct: 1140 RFNNVGIPNGATITGAYVEFTSQDNDSGSSSVTIYGEDVDNASTFTTDSTNISSRTSTSA 1199 Query: 1879 SRSVTLK-WTEPESNGGSPITNYI-IEFKTVKGKSWTKIVTVGGSVHEHCIENI-KEKDE 1935 + S ++ W+E E + + + + I + V W V G+ E++ + D Sbjct: 1200 TVSWSISDWSENEISSDTQTPSLVSIVQEIVNRGGW-----VSGNSLALIFEDVNSDNDR 1254 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 A+++ L + VP PT L G V+ SW P +GG Sbjct: 1255 DALSYDADSSEAPRL-----IITYTAELGVPGAPT-NLTAES-GDEQVLLSWAPPASNGG 1307 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 + + Y I D G +T + L+ +Y R+ A N G + Sbjct: 1308 SAITDYIIEYNDGNGWQTFNDG-TSTDTTDVAVTGLTNGQSYDFRVSAVNTEGTGD 1362 Score = 39.9 bits (89), Expect = 0.75 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 8/128 (6%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNV---TILDKPSPPGKPNILEIDSSSINIC 1400 S T+ + N D +++ + +N NV T PS P P E + + + Sbjct: 3585 SYTVTGLTNGDTYYFRI-ISSNVIDDSAPSNVLSQTPATTPSEPLNP-AAEPGPNQVEVS 3642 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRAYAVNE 1458 W P + G + I YYVV Y D W + S I L + Y F +A N+ Sbjct: 3643 WTLPASDGGAEIEYYVVRY-STDGGSWTEEQTANGNTFSLVIDELTNGTPYLFEIFAHND 3701 Query: 1459 VDISDASE 1466 V D S+ Sbjct: 3702 VGDGDISD 3709 Score = 39.5 bits (88), Expect = 0.99 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 1339 DSKSASLTIKKVENTDAGI-YKLRLE--NNCGHADVEMNVTILDKPSPPGKPNILEIDSS 1395 D +S T V + G+ +K R+ N G+A V +P P I E+++ Sbjct: 1713 DGQSIDTTDVPVTGLENGVLHKFRVYAVNALGNATPSNEVEATPARAPDA-PVITELNAG 1771 Query: 1396 S--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----KTQTSIQNLKTNSSY 1449 I + W P++ G S I Y +E+ D + + ++ T ++ L +Y Sbjct: 1772 DGQIEVIWSTPDDGGES-IDEYRLEWSTNDFSSILDDVTLSGNPPDTTYTVTGLTNGDTY 1830 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETK--IQSPTV-EKPLKNITTEPNE 1497 FR A+N+VD SD S+ V K + +P V + L + PN+ Sbjct: 1831 YFRVIAINDVDESDPSDVESAIPVTVPAKPVLNTPVVGDSSLTVSWSAPND 1881 Score = 39.5 bits (88), Expect = 0.99 Identities = 35/157 (22%), Positives = 65/157 (41%), Gaps = 8/157 (5%) Query: 1342 SASLTIKKVENTDAGIYKLRL--ENNCGHADVE-MNVTILDKPSPPGKPNILEIDSSSIN 1398 + S T+ + N + + + ENN + + T L P+ PG D ++ Sbjct: 2011 ATSTTVTGLTNNETYSFTITATNENNLTSTPSDPVTSTPLGAPAAPGNLTPTPGDKQ-VD 2069 Query: 1399 ICWDEPENTGNSTIIYYVVEYQE----IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + W +P+ G+ II Y V ++ + T I T + L + +Y F Sbjct: 2070 LTWTQPDLNGSGDIISYTVTVRDPSGAVVQTIVIGDDEALTTSYLVTGLTNSVNYTFEVT 2129 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 A NE +++ ++ TT + +I +PT E K + Sbjct: 2130 ATNENNLTSSAATTTSTPLGAPGQIDTPTAESGDKQV 2166 Score = 39.5 bits (88), Expect = 0.99 Identities = 24/81 (29%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQ---EIDTTEWISVKNITKTQTSIQNLKTNSS 1448 I + I++ W+ P TG ++I Y +E Q E D T ++ T S L +S Sbjct: 4348 ISDTEIDLEWNAPLLTGGASIDGYQIERQAEGEADFTIIVADTGSADTTYSDTGLDRGTS 4407 Query: 1449 YRFRAYAVNEVDISDASETTE 1469 Y +R A+ + + D S T E Sbjct: 4408 YTYRVAAITDAGVGDTSSTAE 4428 Score = 38.3 bits (85), Expect = 2.3 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 3/85 (3%) Query: 1375 VTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 VT + S P P I ++ +++ W P N G S I YVVEY + Sbjct: 983 VTYSFEASAPSAPTNLIATAGNTDVSLSWTAPFN-GGSDITDYVVEYSSGSGWNTFADGT 1041 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVN 1457 T T ++ L + Y FR AVN Sbjct: 1042 STDTTATVTGLTNDQEYSFRVSAVN 1066 Score = 38.3 bits (85), Expect = 2.3 Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 14/141 (9%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEID--SS 1395 +S + +T+ + N +++ N G D +V + + P+ G P L ++ Sbjct: 4587 ESTTPEITVTGLNNGQEYLFRAVAVNGVGPGDE--SVPVAETPAALSGNPTDLVATRGNT 4644 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEW---ISVKNITK------TQTSIQNLKTN 1446 +++ W P TG + Y+VEY + ++ S + +T T T I L+ Sbjct: 4645 QVSLTWAAPAVTGGVPVTSYIVEYTDDANGDFGANPSSQTVTSETLPVPTNTIINGLQNG 4704 Query: 1447 SSYRFRAYAVNEVDISDASET 1467 +Y FR AVN S S T Sbjct: 4705 VTYTFRVIAVNTAGPSGPSNT 4725 Score = 38.3 bits (85), Expect = 2.3 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 9/133 (6%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVE--MNVTILDKPSPPGKPNILEIDSSSINICW 1401 S I + N +++ EN+ G DV T + P + I + I + W Sbjct: 5696 SAIITGLTNGQTYEFRVSAENDVGVGDVSDVATATPATASNAPTALSATAISGTEITLSW 5755 Query: 1402 DEPENTGNSTIIYYVVEYQEID------TTEWISVKNI-TKTQTSIQNLKTNSSYRFRAY 1454 P+NTG I Y++E + D TT +S+ + T T + L ++Y +R Sbjct: 5756 IAPQNTGGFAITGYLIERHDGDGNFDDVTTLSVSLPPLPTDTTFTDTGLSQGTTYTYRVS 5815 Query: 1455 AVNEVDISDASET 1467 AV ++ AS T Sbjct: 5816 AVTQLGPGIASGT 5828 Score = 37.1 bits (82), Expect = 5.3 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%) Query: 1382 SPPGKPNILEIDSS-----SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 +P G P+ ID + + + W+ P N G + I Y++E + + E + T Sbjct: 1370 TPAGVPDAPVIDEALGGNGQVYLTWEHPPNNG-AAITDYIIEVNDGNGWEVFNDGTSTNR 1428 Query: 1437 QTSIQNLKTNSSYRFRAYAVN 1457 ++ NL+ +Y FR AVN Sbjct: 1429 FVTVDNLENGETYSFRVKAVN 1449 Score = 36.3 bits (80), Expect = 9.2 Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 10/134 (7%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEID--SSSINICW 1401 S ++ +EN +K+R + + + +P P LE + + + W Sbjct: 5083 SYPVEDLENARTYSFKVRANSIASFGPFSNTLDAVPFTTP-NAPTDLEATRGNGEVTLQW 5141 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ----TSIQNLKTNSSYRFRAYAVN 1457 ++P+ G S I YVVEY + +T + T I L + Y FR AVN Sbjct: 5142 NKPDFNGGSLITSYVVEYSSDSFATDPESQTVTPSDDPITTVISGLDNGTLYSFRVKAVN 5201 Query: 1458 ---EVDISDASETT 1468 E +SD + T Sbjct: 5202 AAGEGALSDIATAT 5215 >UniRef50_Q4STB1 Cluster: Chromosome 11 SCAF14249, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11 SCAF14249, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 495 Score = 134 bits (323), Expect = 3e-29 Identities = 98/380 (25%), Positives = 175/380 (46%), Gaps = 23/380 (6%) Query: 1600 PPPE---VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 PP E V W++ G+++++ I + S + ++ RS + + I+ N G + Sbjct: 32 PPQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEIRIQIKNLFGVAEA 91 Query: 1657 EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV 1716 L V D+PS PE PV E + + I+W PP DDGG +T Y IE+ + + W K+ Sbjct: 92 TSQLIVLDRPSPPEAPVETVETTSSIIVIKWNPPRDDGGSAVTNYIIERQQVGQSLWKKL 151 Query: 1717 ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 +V D + + + +Y +R+ A+N G S++LE++ ++ + + S Sbjct: 152 GNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETKDSIMAGVM-ILSGPPGTPKV 210 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKW----KXXXXXXXXXARIQKLSI 1831 + + +TW P E + G PII Y +E K++ +W +++++ Sbjct: 211 GSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIALNDVSDPIEDVKYAVKEVTE 270 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP--SQPRNFVVSESTSRSVTLKWTEP 1889 Y+FR+ A NE G+ P + P P +FVV + SV +K Sbjct: 271 GAEYEFRVSAINESGSGDPSPPSAMVCAKNPNLRPCFKDPEDFVVVRA-GNSVRVKVCY- 328 Query: 1890 ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 E+ IT ++ + + + W +++ G + + CI + K D I+ I A+N+VG + Sbjct: 329 EAEPPPEIT-WMKDDEPI--SPWIQVINTEG-MSQLCIPSSKRSDSAIYTIKAKNSVGEA 384 Query: 1950 LPTESQSVRLEKHATVPSPP 1969 L +E TV SPP Sbjct: 385 LHD------IEVRVTVHSPP 398 Score = 102 bits (244), Expect = 1e-19 Identities = 93/403 (23%), Positives = 167/403 (41%), Gaps = 23/403 (5%) Query: 1282 EVVEFPPK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 +V EF + + + + ++ G + T + + W IK K + Sbjct: 1 DVPEFDTEDLCKFSKPVIVRVGQNATFKMSFPPQESLVVSWFREGSEIKDGGGVKIVREL 60 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI 1399 + L + +DAG +++++N G A+ + +LD+PSPP P +E SS I I Sbjct: 61 NHSRLLFRDCLRSDAGEIRIQIKNLFGVAEATSQLIVLDRPSPPEAPVETVETTSSIIVI 120 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVN 1457 W+ P + G S + Y++E Q++ + W + N++ +T +N+ Y +R YA N Sbjct: 121 KWNPPRDDGGSAVTNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAEN 180 Query: 1458 EVDISDASETTEYYK---VIKETKIQSP---TVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 + +SD+ ET + +I +P +V K N+T P ED + I G + + Sbjct: 181 QEGLSDSLETKDSIMAGVMILSGPPGTPKVGSVSKTCINLTWTPPEDDKGMPIIGYLLEK 240 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS------CVV 1565 + + L E+ ++ A N+ G + S C Sbjct: 241 RKKDTTEWIALNDVSDPIED-VKYAVKEVTEGAEYEFRVSAINESGSGDPSPPSAMVCAK 299 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 +P + + + G+ V E PPPE+ W K+ + + E Sbjct: 300 NPNLRPCFKDPEDFVVV--RAGNSVRVKVCYEAEPPPEITWMKDDEPI--SPWIQVINTE 355 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDKP 1666 S + I KRS S+ YTI+A N+ G + +EV + V+ P Sbjct: 356 GMSQLCIPSSKRSDSAIYTIKAKNSVGEALHDIEVRVTVHSPP 398 Score = 101 bits (242), Expect = 2e-19 Identities = 104/473 (21%), Positives = 184/473 (38%), Gaps = 45/473 (9%) Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC------------ 1268 P E+L V+W+++ S I+D ++ ++ L+ R C D E Sbjct: 33 PQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEIRIQIKNLFGVAEAT 92 Query: 1269 ---VLLDAKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVT-LLVDYQAFPQPNDEWIV 1323 ++LD S + VE VE I+ + R GS VT +++ Q Q + + Sbjct: 93 SQLIVLDRPSPPEAPVETVETTSSIIVIKWNPPRDDGGSAVTNYIIERQQVGQSLWKKLG 152 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 N K C + K + I EN + L +++ + V IL P Sbjct: 153 NVSADKTCFRDRNVTHGKKYNYRIY-AENQEGLSDSLETKDS-----IMAGVMILS--GP 204 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT----KTQTS 1439 PG P + + + IN+ W PE+ II Y++E ++ DTTEWI++ +++ + + Sbjct: 205 PGTPKVGSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIALNDVSDPIEDVKYA 264 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 ++ + + Y FR A+NE D S + V + P + P + + Sbjct: 265 VKEVTEGAEYEFRVSAINESGSGDPSPPSA--MVCAKNPNLRPCFKDPEDFVVVRAGNSV 322 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 + + P P++TW +D + + E Y A N G Sbjct: 323 RVKVCYEAEPPPEITWMKDDEPISPWIQVINTEGMSQLCIPSSKRSDSAIYTIKAKNSVG 382 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 E V +T+ + G + +T + G P P V WY N + +DK Sbjct: 383 EALHDIEVR------VTVHSP------PKGYQLYMTCAVRGCPTPSVSWYLNDVCINSDK 430 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 Y IT + I ++ + + +Y + A N+ G + + V K + E Sbjct: 431 NYYITNSCGVCSMYILRVRPTDNGEYKVVALNSLGKAECATKIIVRGKHIRTE 483 Score = 99.1 bits (236), Expect = 1e-18 Identities = 61/219 (27%), Positives = 103/219 (47%), Gaps = 8/219 (3%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 + RI +N G + + ++ + +PP P V E+TS + +KW P +GGS Sbjct: 77 EIRIQIKNLFGVA---EATSQLIVLDRPSPPEAPVETV--ETTSSIIVIKWNPPRDDGGS 131 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 +TNYIIE + V W K+ V N+ + +RI AEN G+S E++ Sbjct: 132 AVTNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETK 191 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + + PP P ++ V + +W PE D G P++GY + R T W+ Sbjct: 192 DSIMAGVMILSGPPGTP-KVGSVSKTCINLTWTPPEDDKGMPIIGYLLEKRKKDTTEWIA 250 Query: 2016 VGKVD--VNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + V + +K+ +++++E Y R+ A NE G +P Sbjct: 251 LNDVSDPIEDVKYAVKEVTEGAEYEFRVSAINESGSGDP 289 Score = 77.0 bits (181), Expect = 5e-12 Identities = 42/119 (35%), Positives = 67/119 (56%), Gaps = 5/119 (4%) Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 RI +N GV+ T SQ + L++ PSPP AP+E S+I++ W P DGG+ + Sbjct: 79 RIQIKNLFGVAEAT-SQLIVLDR----PSPPEAPVETVETTSSIIVIKWNPPRDDGGSAV 133 Query: 1999 LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 Y I + V +++W ++G V + F R+++ Y RIYA N+ GLS+ LE+ + Sbjct: 134 TNYIIERQQVGQSLWKKLGNVSADKTCFRDRNVTHGKKYNYRIYAENQEGLSDSLETKD 192 Score = 64.5 bits (150), Expect = 3e-08 Identities = 60/245 (24%), Positives = 100/245 (40%), Gaps = 23/245 (9%) Query: 700 VKKFQEGT---YTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 VK+ EG + V A+N G + S P + P +P ++VR G SV + Sbjct: 265 VKEVTEGAEYEFRVSAINESGSGDPSPPSAMVCAKNPNLRPCFKDPEDFVVVRAGNSVRV 324 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 P P ITW K+++P+ + + S + K D +YT+KA+NS G Sbjct: 325 KVCYEAEPPPEITWMKDDEPISPWIQVINTEGMSQLCIPSSKRSDSAIYTIKAKNSVG-- 382 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 A+ +E ++ P + + + V P PS++WY N+ I+ Sbjct: 383 --EALHDIEVRVTVHSPPKGY-------------QLYMTCAVRGCPTPSVSWYLNDVCIN 427 Query: 875 PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 + + I V D+G+YK VA NS GK+ ++ + + + L Sbjct: 428 SDKNYYITNSCGVCSMYILRV-RPTDNGEYKVVALNSLGKAECATKIIVRGKHIRTELTL 486 Query: 935 QKSYE 939 YE Sbjct: 487 MICYE 491 Score = 45.6 bits (103), Expect = 0.015 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P G + C V G P P ++W+ I +++ + + V ++ I V P D G + Sbjct: 398 PKGYQLYMTCAVRGCPTPSVSWYLNDVCINSDKNYYI-TNSCGVCSMYILRVRPTDNGEY 456 Query: 582 TCVAKNAAGFASSTTELIV 600 VA N+ G A T++IV Sbjct: 457 KVVALNSLGKAECATKIIV 475 Score = 42.7 bits (96), Expect = 0.11 Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 26/193 (13%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F V G+ + ++ A P P+I W+ E I P I V M C Sbjct: 305 PCFKDPEDFVVVRAGNSVRVKVCYEAEPPPEITWMKDDEPISP--WIQVINTEGMSQLC- 361 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 I + K+ YT+ A N GEA I +++ PP +G + Sbjct: 362 ---IPSSKRSDSAIYTIKAKNSVGEALHDIEVRVTV--HSPP------------KGYQLY 404 Query: 754 LSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 ++ V G P P+++W N N T S G S+ IL+ + D G Y + A N Sbjct: 405 MTCAVRGCPTPSVSWYLNDVCINSDKNYYITNSCG-VCSMYILRVRPT-DNGEYKVVALN 462 Query: 810 SEGIAETSAVITV 822 S G AE + I V Sbjct: 463 SLGKAECATKIIV 475 Score = 41.9 bits (94), Expect = 0.19 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Query: 1118 VNKGNKATFEIELTKGDALV-RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V G ATF++ ++LV WF++GSEI+ +++ + +L DC DAGE Sbjct: 19 VRVGQNATFKMSFPPQESLVVSWFREGSEIKDGGGVKIVRELNHSRLLFRDCLRSDAGEI 78 Query: 1177 SCEVGN 1182 ++ N Sbjct: 79 RIQIKN 84 >UniRef50_UPI0000660A1C Cluster: Homolog of Gallus gallus "Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast-isoform).; n=1; Takifugu rubripes|Rep: Homolog of Gallus gallus "Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast-isoform). - Takifugu rubripes Length = 844 Score = 132 bits (320), Expect = 8e-29 Identities = 105/469 (22%), Positives = 207/469 (44%), Gaps = 20/469 (4%) Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF--EKRGHIRKLY 1075 +F+ K+QD + +E++ A+ E I+ + W + I + K+D + I L Sbjct: 269 DFLYKIQDVKAEEREDAVFECVISQPLKKITW-KGKNIPLEQGEKFDILVSEDMLIHTLV 327 Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGD 1134 +++ D+G Y+ + SC+A + V E E R++ + K +A +++ K Sbjct: 328 VKDCMPLDKGIYAAVAGLASCSAWLVVEE--SEAKARVEAEIKAKARAEAKAKLKAKKKS 385 Query: 1135 ALVRWFKDGSEI--QFSNHIQLTID----GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188 + K+ ++ + +L+ D G ++++ + D +D + E S + Sbjct: 386 SATEKGKEKQKMVKKAKAKAELSADSEDKGDSEEIEDIEEDTNDDNDMDGEQEESVKEDV 445 Query: 1189 LTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247 V + + FT L + + +A L ++ E D WYK I T++ ++ D Sbjct: 446 EGVPTGAGVYFTSGLCDVTAI-LGANAELVCKLSSEECDGVWYKDGKEITATDEICIVKD 504 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEF--PPKIVDYEREYRIKRGSDV 1305 R LII+ C E+D +Y C K+ LKVE P + ++++ +IK G Sbjct: 505 HNFRKLIIKNCKEEDAGKYRCEADGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSA 564 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 TL + + +W + + + + K S L + K +G K++++N Sbjct: 565 TLKISFVGREPMKVQWYHEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNE 624 Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425 CG + ++ +L P PP P I+ IN+ W P NTG + ++ Y VE ++ + Sbjct: 625 CGTTEATTDIVVLAFPGPPAAPKIVSAFKDCINLVWIAPSNTGGTNLLGYNVEKRKNGSN 684 Query: 1426 EWISV----KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 W V + I + + +++++ Y FR A+N + S +E+ Sbjct: 685 LWSFVNPPDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSPPSEF 733 Score = 77.4 bits (182), Expect = 4e-12 Identities = 87/386 (22%), Positives = 137/386 (35%), Gaps = 24/386 (6%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXX 1543 L ++T + EL C V WY+DGK++ N Sbjct: 460 LCDVTAILGANAELVCKLSSEECDGV-WYKDGKEITATDEICIVKDHNFRKLIIKNCKEE 518 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-----KHKVGDEWLVTAVIEG 1598 Y+C A G +T ++ ++ P I+ +D+K+ K K G + G Sbjct: 519 DAGKYRCEA---DGR-KTEAMLKVEDPP--RINPDDLKEFQKPVKIKTGKSATLKISFVG 572 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P +V WY G +L D I + + + + +R S + I+ N GT+ Sbjct: 573 REPMKVQWYHEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEATT 632 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 + V P P P I+ ++ + + W P + GG L Y +EK + +N W V Sbjct: 633 DIVVLAFPGPPAAPKIVSAF-KDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNP 691 Query: 1719 VDRDV--ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 D + + Y ++ + E EY FRV A N G E V P Sbjct: 692 PDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRV 751 Query: 1777 XXIDNESVYITWF--PSEKNGGSPIIDYKVEIK-QEGKKWK--XXXXXXXXXARIQKLSI 1831 ++ + W E+ Y VE + E +W I L Sbjct: 752 TDSTYTTLSLGWTKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKS 811 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKI 1857 Y R+ A NE G P D+ I Sbjct: 812 MAMYWVRVVATNEGGDGEPQDLDNYI 837 Score = 66.9 bits (156), Expect = 6e-09 Identities = 179/861 (20%), Positives = 326/861 (37%), Gaps = 75/861 (8%) Query: 937 SYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD- 993 S +EGK V+ + T + W N EI H+ + +G D Sbjct: 16 SITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSGEHQLQIPDVSADE 75 Query: 994 VGVIKCIVKDQE-----TSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETADV 1047 KC ++ T+T+ V++ E + ++ D + KE++ ++E + + +V Sbjct: 76 ADTYKCFATNEYGKAIVTATLNVIEAEDFKKALKNKIDIDAKEEN----KMEADEKFFEV 131 Query: 1048 VW---ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVE 1104 + ++D E I + DF RG ++KL + E E +L + V Sbjct: 132 LMSAEKKDYESICIQYGVTDF--RGMLKKL--NEKKIEREKEQEKVLFPHVFFLKEYRVN 187 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 T + N K TF L K D ++ F ++I+ L GKK Sbjct: 188 ------TMIWNLIFLLCWKMTFSSLLFKQDGVMIPFDADTDIKHG----LKQVGKKYVFS 237 Query: 1165 IYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET 1224 I D +D+G Y EV K + + P+++F ++ + + DA I Sbjct: 238 INGVDPEDSGLYQVEVDGVKVFS-TDFKVPNVDFLYKIQD-VKAEEREDAVFECVISQPL 295 Query: 1225 LDVTWYKKKSVIEDTEKFTLI--SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 +TW K +E EKF ++ D+ TL+++ C D+ Y V A + L VE Sbjct: 296 KKITWKGKNIPLEQGEKFDILVSEDMLIHTLVVKDCMPLDKGIYAAVAGLASCSAWLVVE 355 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDS- 1340 E ++ E E + K ++ + + ++ K++KK K + S DS Sbjct: 356 ESEAKARV---EAEIKAKARAEAKAKLKAKKKSSATEKGKEKQKMVKKAKAKAELSADSE 412 Query: 1341 -KSASLTIKKV-ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 K S I+ + E+T+ + DVE T G ++ I ++ Sbjct: 413 DKGDSEEIEDIEEDTNDDNDMDGEQEESVKEDVEGVPTGAGVYFTSGLCDVTAILGANAE 472 Query: 1399 -ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAV 1456 +C E ++Y + +EI T+ I VK+ + I+N K + ++R A Sbjct: 473 LVCKLSSEECDG---VWY-KDGKEITATDEICIVKDHNFRKLIIKNCKEEDAGKYRCEA- 527 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 D +T KV +I +++ K + + + L F G KV WY Sbjct: 528 ------DGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSATLKISFVGREPMKVQWY 581 Query: 1517 RDGKK-LKTAKATYENRXXXXXXXXX---XXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 +G++ L+ E K N+ G E + + + P Sbjct: 582 HEGEELLEDTNIKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEATTDIVVLAFPG 641 Query: 1573 ITISNEDIKQ-KHKVGDEWLVTAVIEG--IPPPEVIWYKNGNKL---ENDKEYNITTKEK 1626 + + + K + W+ + G + V KNG+ L N + I K+ Sbjct: 642 PPAAPKIVSAFKDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNPPDEPIREKK- 700 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-VYDK-PSKPEGPVIMREISRESVT 1684 +K++ ++ + A N +G+ + V+ + P KP G VI ++ + T Sbjct: 701 ---YAVKDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRVTDSTYT 757 Query: 1685 ---IEWKPPLDDGGL--ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 + W P ++ + E Y +E ++ W + + +Y I L Y Sbjct: 758 TLSLGWTKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKSMAMYWV 817 Query: 1740 RVIAQNPVGFSEALESEPIVI 1760 RV+A N G E + + +I Sbjct: 818 RVVATNEGGDGEPQDLDNYII 838 Score = 61.7 bits (143), Expect = 2e-07 Identities = 79/369 (21%), Positives = 141/369 (38%), Gaps = 41/369 (11%) Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT----- 1659 +WYK+G ++ E I + IK K + KY EA + ++V Sbjct: 485 VWYKDGKEITATDEICIVKDHNFRKLIIKNCKEEDAGKYRCEADGRKTEAMLKVEDPPRI 544 Query: 1660 ----LKVYDKPSKPE-GPVIMREIS---RESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 LK + KP K + G +IS RE + ++W ++ LE T IEK Sbjct: 545 NPDDLKEFQKPVKIKTGKSATLKISFVGREPMKVQWYHEGEEL-LEDTNIKIEKSSTHTQ 603 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 V T C +K + ++ +N G +EA + IV+ P+ Sbjct: 604 L----------VLTKCRRKSSGE----IKIKIKNECGTTEA--TTDIVVLAFPGPPAAPK 647 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI 1831 + + + W GG+ ++ Y VE ++ G R +K ++ Sbjct: 648 IVSAF----KDCINLVWIAPSNTGGTNLLGYNVEKRKNGSNLWSFVNPPDEPIREKKYAV 703 Query: 1832 NTT-----YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 Y+FR+ A N G+ P + + PP + + V++ST +++L W Sbjct: 704 KDVVEGIEYEFRVSAINISGSGEPSPPSEFVFARDPKKPPGKVIDLRVTDSTYTTLSLGW 763 Query: 1887 TEP--ESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 T+P E Y +EF+ + W++ + ++ + I +K R+ A N Sbjct: 764 TKPKEEEEVQDEAKGYFVEFRPAEDPEWSRCNSSAIIMNSYTIMGLKSMAMYWVRVVATN 823 Query: 1945 TVGVSLPTE 1953 G P + Sbjct: 824 EGGDGEPQD 832 Score = 60.5 bits (140), Expect = 5e-07 Identities = 56/237 (23%), Positives = 95/237 (40%), Gaps = 14/237 (5%) Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 + +I +NE GT+ T+D I + PP+ P+ +VS + + L W P + GG+ Sbjct: 616 EIKIKIKNECGTT-EATTD--IVVLAFPGPPAAPK--IVS-AFKDCINLVWIAPSNTGGT 669 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPTE 1953 + Y +E + W+ + + E + ++++ E E FR+SA N G P+ Sbjct: 670 NLLGYNVEKRKNGSNLWSFVNPPDEPIREKKYAVKDVVEGIEYEFRVSAINISGSGEPSP 729 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS--WGTP--EWDGGAPLLGYNIAIRDVT 2009 + PP +++R+ S S W P E + GY + R Sbjct: 730 PSEFVFARDPK--KPPGKVIDLRVTDSTYTTLSLGWTKPKEEEEVQDEAKGYFVEFRPAE 787 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 W + + I L Y +R+ A NE G EP + D +P G Sbjct: 788 DPEWSRCNSSAIIMNSYTIMGLKSMAMYWVRVVATNEGGDGEPQDLDNYIIAMPPPG 844 Score = 50.0 bits (114), Expect = 7e-04 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 3/115 (2%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGE 886 E P F + IT++E + A V NP P++TW RNN EI I + Sbjct: 3 EGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSG 62 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 +L I +V ++ ++ YKC A+N GK+ A + + +E F K L+ + + Sbjct: 63 EHQLQIPDVSAD-EADTYKCFATNEYGKAIVTATLNV-IEAEDFKKALKNKIDID 115 Score = 49.2 bits (112), Expect = 0.001 Identities = 82/360 (22%), Positives = 138/360 (38%), Gaps = 34/360 (9%) Query: 758 VVGNPRPTITWCKNNKPVKA-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 V+ P ITW N P++ + D H++ ++K D+G+Y A G Sbjct: 290 VISQPLKKITWKGKNIPLEQGEKFDILVSEDMLIHTL-VVKDCMPLDKGIYAAVA----G 344 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-- 870 +A SA + VEE +E A I K K K + T + Sbjct: 345 LASCSAWLVVEE-SEAKARVEAEIKAKARAEAKAKLKAKKKSSATEKGKEKQKMVKKAKA 403 Query: 871 --EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEK 927 E+ + SE + + E+IE TN D+++D + V + G + G T + Sbjct: 404 KAELSADSEDKGDSEEIEDIE-EDTNDDNDMDGEQEESVKEDVEGVPTGAGVYFTSGLCD 462 Query: 928 VTFVKHLQKSYETEEGKTVILECQ-TSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 VT + G L C+ +S WY + KEI+ D I+++ Sbjct: 463 VTAIL----------GANAELVCKLSSEECDGVWYKDGKEITATDEICIVKDHNFRKLII 512 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKE---TIPEFIRKLQ-DFEVKEKDVAILEVE-IN 1041 D G +C ++T ML V++ P+ +++ Q ++K A L++ + Sbjct: 513 KNCKEEDAGKYRCEADGRKTEAMLKVEDPPRINPDDLKEFQKPVKIKTGKSATLKISFVG 572 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 E V W +GE + N EK +L + GE +++E T E T Sbjct: 573 REPMKVQWYHEGEELLEDTN-IKIEKSSTHTQLVLTKCRRKSSGEIKIKIKNECGTTEAT 631 Score = 48.8 bits (111), Expect = 0.002 Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 10/104 (9%) Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-----KALPTK 781 I G P +P+ S+ +++G+ V+ A VVGNP PT+TW +NN + K L K Sbjct: 1 IPEGMSTPDFTRKPI-SITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDK 59 Query: 782 SDGDTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEE 824 G+ H + I P DE Y A N G A +A + V E Sbjct: 60 GSGE-HQLQI--PDVSADEADTYKCFATNEYGKAIVTATLNVIE 100 Score = 43.6 bits (98), Expect = 0.061 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 1/99 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E P F K +G V F V G P P +TW R I + +Y Sbjct: 3 EGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEIGDERHKILYDKGSG 62 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEA 602 L I +V ++A T+ C A N G A T L ++EA Sbjct: 63 EHQLQIPDVSADEADTYKCFATNEYGKAIVTATLNVIEA 101 Score = 39.9 bits (89), Expect = 0.75 Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 4/105 (3%) Query: 628 ILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 I EG+ P F++KP + + EG ++ +V P P + WL EI DE + + Sbjct: 1 IPEGMSTPDFTRKPISITIQEGKLVVFRAVVVGNPTPTVTWLRNNGEI-GDERHKILYDK 59 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 + L+I +V + TY A N G+A + L + E Sbjct: 60 GSGEH--QLQIPDVSADEADTYKCFATNEYGKAIVTATLNVIEAE 102 Score = 39.9 bits (89), Expect = 0.75 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN-VATLVI 570 F+ K++ + FEC + P +ITW + ++ + F + +D + TLV+ Sbjct: 270 FLYKIQDVKAEEREDAVFECVIS-QPLKKITWKGKNIPLEQGEKFDILVSEDMLIHTLVV 328 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 ++ P D G + V AG AS + L+VE Sbjct: 329 KDCMPLDKGIYAAV----AGLASCSAWLVVE 355 >UniRef50_Q8TD84 Cluster: Down syndrome cell adhesion molecule-like protein 1 precursor; n=63; Euteleostomi|Rep: Down syndrome cell adhesion molecule-like protein 1 precursor - Homo sapiens (Human) Length = 2053 Score = 130 bits (314), Expect = 4e-28 Identities = 317/1535 (20%), Positives = 562/1535 (36%), Gaps = 164/1535 (10%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQIT---WFRQTAIIKPSQDFQMYYDDDNVATL 568 + ++ + + G+ F+C + + ++ W + T I P F + Y L Sbjct: 127 YTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGG----L 182 Query: 569 VIREVFPEDA-GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 I +V EDA T+ C+ K+ ++ T + +G+ ++V D Sbjct: 183 YISDVQKEDALSTYRCITKHK--YSGETRQ--------SNGARLSVT------------D 220 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 E IP T +Q V G + L C P P I WL G + D + I Sbjct: 221 PAESIP-TILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG- 278 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 L I++++ GTY N G A +L + +P V K + Sbjct: 279 -------LTISDLRTEDSGTYICEVTNTFGSAEATGILMVI----DPLHVTLTPKKLKTG 327 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYT 804 G +VILS + G+P TI W +N + V LP ++ G ++ ++ + G Y Sbjct: 328 IGSTVILSCALTGSPEFTIRWYRNTELV--LPDEAISIRGLSNETLLITSAQKSHSGAYQ 385 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A A+ A+I +E+ T P ++ F E V L+ P P++ Sbjct: 386 CFATRKAQTAQDFAIIALEDGT------PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTV 439 Query: 865 TWYRNNE-IISPSETITQNF---DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 TW ++E I+ T + DG I + D G Y+C A N G + + AR Sbjct: 440 TWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQAR 499 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQE 978 I+V ++ + ++ G+ ++ C+ S KWY + + +HR+++ E Sbjct: 500 --INVRGPPSIRAM-RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPD-NHRQVVFE 555 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA-ILE 1037 D G C V Q ++ + +Q FE + +L Sbjct: 556 -NGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLY 614 Query: 1038 VEINSETAD----VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 + + D + W +DG++I + E + + L I + S+ G Y+CI + Sbjct: 615 IPCVVSSGDMPIRITWRKDGQVI-ISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 673 Query: 1094 ESCTA---EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS 1149 + T +V +PP + + NQ G + V W Sbjct: 674 AAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQ 733 Query: 1150 NHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNSKCTAI-----LTVEEPSINFT 1199 + + + G+ Q L I +D G Y C+ N T I LTV+ P++ T Sbjct: 734 QYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAM-IT 792 Query: 1200 LRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE--KFTLIS----DVKKRTL 1253 I + + + + + W K +VI+ ++ + + D TL Sbjct: 793 SHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTL 852 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQ 1312 ++ D ++C +++ + +++ V+ PP E E R + + L Q Sbjct: 853 KLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPD--PPELEIREVKARSMNLRWT-Q 909 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSI--DSKSASLTIKKVENTD---AGIYKLRLE--NN 1365 F + I I K K +++ S TI + D A +Y +R+ N Sbjct: 910 RF--DGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNK 967 Query: 1366 CGHADVEMNVTI-LDKPSPPGKP---NILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQ 1420 G ++ +TI ++ +P G P + + S SI + W P + N I Y + Y+ Sbjct: 968 IGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR 1027 Query: 1421 EID--TTEWISVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASE-----TTE 1469 E + S+ + T S + NLK + Y A N +S T E Sbjct: 1028 ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLE 1087 Query: 1470 YYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 +++ ++ + I+ L + G + Y DG+ + T Sbjct: 1088 DVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNIT- 1146 Query: 1530 ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK----QKHK 1585 R + +A+ G+ S V+ IQ K + IK Sbjct: 1147 TTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASS 1206 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 V WL G+ I+ + G+ EY T + RI L R Sbjct: 1207 VVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE--TSPEQLFYRIAHLNRGQQYLLW 1264 Query: 1645 IEASNTA--GTSSVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEW----KPPLDDGGLE 1697 + A +A G SS +VT+ +P G + IS +VT W + P + G Sbjct: 1265 VAAVTSAGRGNSSEKVTI-------EPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1317 Query: 1698 LTKYAIEKHEPDNNRWIKVADVDRDVE---TYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 K D+ + + D R + T ++ + + A N GF Sbjct: 1318 APAVKWTKDSEDSAIPVSM-DGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGF----- 1371 Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKW 1813 + I++ + VP S+ +TW P + NGGS I + ++ ++W Sbjct: 1372 -DTIIVNLLVQVPPDQPRLTVSKT-SASSITLTWIPGD-NGGSSIRGFVLQYSVDNSEEW 1428 Query: 1814 KXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 K + ++ L T Y+ ++ A+N +G+ + T G+ + F Sbjct: 1429 KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLF 1488 Query: 1873 VVSESTSRSVTLK-WTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 ST + L+ W +NGG PIT ++E++ KG +W S E + ++ Sbjct: 1489 THINSTHARLNLQGW----NNGGCPITAIVLEYRP-KG-TWAWQGLRANSSGEVFLTELR 1542 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 E R+ A N+ G T + +T+P Sbjct: 1543 EATWYELRMRACNSAGCGNETAQFATLDYDGSTIP 1577 Score = 120 bits (289), Expect = 4e-25 Identities = 221/1098 (20%), Positives = 417/1098 (37%), Gaps = 124/1098 (11%) Query: 1022 KLQDFEVKEKDVAILEVEINSETADVV----WERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 +++D +VA+ + I S + V WE+D I P+ + G LYI Sbjct: 130 RVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHRFFITYHGG----LYIS 185 Query: 1078 NTSVHDE-GEYSCILRD-------ESCTAEVTVV---ELPPEIITRLQNQKVNKGNKATF 1126 + D Y CI + +S A ++V E P I+ +Q+V G+ T Sbjct: 186 DVQKEDALSTYRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGH--TV 243 Query: 1127 EIELTKGD---ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV--- 1180 E+ T +RW KDG + + I G L I D +D+G Y CEV Sbjct: 244 ELPCTASGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTEDSGTYICEVTNT 299 Query: 1181 -GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYKKKSVIED 1238 G+++ T IL V +P ++ TL P+ + + L+ + + WY+ ++ Sbjct: 300 FGSAEATGILMVIDP-LHVTLT-PKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLP 357 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYERE 1296 E + I + TL+I + Y C T + + + + P+IV E Sbjct: 358 DEAIS-IRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSE 416 Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT--- 1353 + G +L+ + P P W ++ + I + + + + S TI + T Sbjct: 417 KVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQ 476 Query: 1354 --DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 D G+Y+ N G A+ + + + PS NI + I N Sbjct: 477 IRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLI------NCRVIG 530 Query: 1412 IIYYVVE-YQEI----DTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 YY ++ Y++ D + +N T T +Q Y ++ IS + Sbjct: 531 YPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVH 590 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525 ++ P + +P + + + + C+ P ++TW +DG+ + + Sbjct: 591 VA----------VKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG 640 Query: 1526 KA-TYENRXXXXXXXXXXXXXXX---YKCIAFNDHGEV--ETSCVVGIQQKPVITISNED 1579 T E++ Y CIA N V E +V + + V+ +N+D Sbjct: 641 SGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD 700 Query: 1580 IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN---ITTKEK---TSVIRIK 1633 G ++ ++G PPP+V+W K+ N ++Y+ +T + + S + I+ Sbjct: 701 ----GIYGKAGVLNCSVDGYPPPKVMW-KHAKGSGNPQQYHPVPLTGRIQILPNSSLLIR 755 Query: 1634 ELKRSHSSKYTIEASNTAGTS---SVEVTLKVYDK-PSKPEGPVIMREISRE-SVTIEWK 1688 + Y +ASN GT S+ +T+K+ S P + ++ ++E + T + Sbjct: 756 HVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGE 815 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD-----VETYCIQKLNENCEYMFRVIA 1743 P+ + ++ D +R ++ A +D V T ++ + F A Sbjct: 816 RPI------IIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHA 869 Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 N G L + ++ D P + S+ + W +G S I + Sbjct: 870 INSYGEDRGLIQ--LTVQEPPDPPELEIRE-----VKARSMNLRW-TQRFDGNSIITGFD 921 Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIGTSLPYTSDDKIT 1858 +E K + W I + +I + Y R+Y+ N+IG S P ++T Sbjct: 922 IEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEP---SKELT 978 Query: 1859 IG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKT----VKGKSW 1912 I + P P + + TS+S+ + W P+ I Y I ++ G+ Sbjct: 979 ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYS 1038 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 + G + ++N+K+ + + A N G P+ S+ + VPS P Sbjct: 1039 IVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSE-INATTLEDVPSQPPEN 1096 Query: 1973 LEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV-TKTMWMEVGKVDVNTLKFNIRD 2030 + + S++ + SW P L GY + + W E+ + + +R Sbjct: 1097 VRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRG 1156 Query: 2031 LSENHTYMIRIYARNEIG 2048 + + Y +++ A + G Sbjct: 1157 MEKFTNYSVQVLAYTQAG 1174 Score = 90.2 bits (214), Expect = 5e-16 Identities = 157/749 (20%), Positives = 266/749 (35%), Gaps = 49/749 (6%) Query: 651 ILLECRLVAIPEPDIAW-LFKGEEIVPDENIS-VAIESDMHMYCSVLKITNVKKFQEGTY 708 +++ C P + W L G++I +I V + +Y N + Y Sbjct: 43 VVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFN-SFIHDNDY 101 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 A N G+ P + ++K +EP V +E +SM L V ++ Sbjct: 102 FCTAENAAGKIRSPNI-RVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVS 160 Query: 768 WCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W K+ P G + + K + T + E A ++V + Sbjct: 161 WEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLSVTD 220 Query: 825 PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 P E P ++ F V T++L + P+P+I W ++ + T+ Sbjct: 221 PAESI---PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTKRIT 277 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEG 943 G L I+++ +E DSG Y C +N+ G + + G + ID VT K +T G Sbjct: 278 G----LTISDLRTE-DSGTYICEVTNTFGSAEATGILMVIDPLHVTLTP---KKLKTGIG 329 Query: 944 KTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 TVIL C S + +WY N E+ D I+ G +C Sbjct: 330 STVILSCALTGSPEFTIRWYRNT-ELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388 Query: 1002 -KDQETS---TMLVVKETIPEFIRKLQDFEVKE-KDVAILEVEINSETADVVWERDGEII 1056 + +T+ ++ +++ P + + V + +++ + V W D E I Sbjct: 389 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPI 448 Query: 1057 ----KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEI 1109 + N+Y I + + + D G Y C R+ +AE V PP I Sbjct: 449 VRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSI 508 Query: 1110 ITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 ++N G + ++W+KD + NH Q+ + KL Sbjct: 509 -RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLP-DNHRQVVFENGTLKLTDVQK 566 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL----TVEIPDET 1224 +D+ GEY C V +I ++ + F PA+ L V D Sbjct: 567 GMDE-GEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMP 625 Query: 1225 LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-V 1283 + +TW K VI T+ S +L I + YTC+ +A +T + + + Sbjct: 626 IRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLI 685 Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDS-- 1340 V PP+ V G L +P P W + H P Sbjct: 686 VRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQ 745 Query: 1341 --KSASLTIKKVENTDAGIYKLRLENNCG 1367 ++SL I+ V D G Y + N G Sbjct: 746 ILPNSSLLIRHVLEEDIGYYLCQASNGVG 774 Score = 61.7 bits (143), Expect = 2e-07 Identities = 96/440 (21%), Positives = 167/440 (37%), Gaps = 36/440 (8%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678 NITT + +R E ++S + + A AG L + K P P ++ + Sbjct: 1144 NITTTRERVELRGMEKFTNYSVQ--VLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVP 1201 Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736 S SV + W PP G+ + KY I P + + + + Y I LN + Sbjct: 1202 SSASSVVVSWLPPTKPNGV-IRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQ 1260 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y+ V A G + SE + I+ A P+ +V W + Sbjct: 1261 YLLWVAAVTSAGRGNS--SEKVTIEPAGKAPAKIISFGG-------TVTTPWMKDVRLPC 1311 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852 + + D +K R+ + N T R + G T+ Sbjct: 1312 NSVGDPAPAVKWTKDSEDSAIPVSMDGHRL--IHTNGTLLLRAVKAEDSGYYTCTATNTG 1369 Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 D I + + PP QPR VS++++ S+TL W P NGGS I +++++ + Sbjct: 1370 GFDTIIVNLLVQVPPDQPR-LTVSKTSASSITLTWI-PGDNGGSSIRGFVLQYSVDNSEE 1427 Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS---P 1968 W K V + S ++++K +++A+N+VG S+ + + H PS Sbjct: 1428 W-KDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG--RISEIIEAKTHGREPSFSKD 1484 Query: 1969 PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNI 2028 I + + + W +GG P+ + R K W G ++ + + Sbjct: 1485 QHLFTHINSTHARLNLQGWN----NGGCPITAIVLEYR--PKGTWAWQGLRANSSGEVFL 1538 Query: 2029 RDLSENHTYMIRIYARNEIG 2048 +L E Y +R+ A N G Sbjct: 1539 TELREATWYELRMRACNSAG 1558 Score = 47.2 bits (107), Expect = 0.005 Identities = 33/108 (30%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQD 555 EK T E AP + TP V+ C G P P + W + + + I S D Sbjct: 1278 EKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMD 1337 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + TL++R V ED+G +TC A N GF + L+V+ P Sbjct: 1338 GHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383 Score = 45.6 bits (103), Expect = 0.015 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%) Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 TV PP P LEIR V + + W T +DG + + G++I ++ + + + +++ Sbjct: 883 TVQEPPDPPELEIREVKARSMNLRW-TQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNIS 941 Query: 2023 TL--KFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + NI DL Y IR+Y+ N+IG SEP Sbjct: 942 PTINQANIVDLHPASVYSIRMYSFNKIGRSEP 973 Score = 44.8 bits (101), Expect = 0.026 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 5/95 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P ++ + G TV+ C GYP P I W + + + + L Sbjct: 226 PTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTK-----RITGLT 280 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 I ++ ED+GT+ C N G A +T L+V PL Sbjct: 281 ISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPL 315 >UniRef50_UPI0000E8095E Cluster: PREDICTED: similar to novel immunoglobulin I-set domain containing protein; n=1; Gallus gallus|Rep: PREDICTED: similar to novel immunoglobulin I-set domain containing protein - Gallus gallus Length = 561 Score = 129 bits (312), Expect = 7e-28 Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 4/280 (1%) Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKR 1068 M V E +F+R L D + + +L E+ DVVW +DG +++P + + + Sbjct: 280 MAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARR-EVRVQ 338 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFE 1127 G R L + D GEY C D+ A +TV V EII LQ+ V +G+ ATF+ Sbjct: 339 GRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATFK 398 Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 ++ D +V W DG + S +Q+ G L + C DA + TA Sbjct: 399 CMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLSTA 458 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISD 1247 L+V+E + F +L + ++ D L VE+ E +V W K+ +++ +K+ + Sbjct: 459 RLSVQEAQVLFVRKLRD-VVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRES 517 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP 1287 +RTL IR + D+ Y C L ++ KL VE E+P Sbjct: 518 GCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVE-REYP 556 Score = 115 bits (277), Expect = 1e-23 Identities = 117/528 (22%), Positives = 200/528 (37%), Gaps = 39/528 (7%) Query: 864 ITWYRNNEIIS----PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 + WY++ E + P E + G EL + DSG Y C A++ +S Sbjct: 17 VKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPG-DSGCYVCDAASDRMVTS--V 73 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQE 978 V ++ + Q E +EG +V L Q S T + +W + + + + E Sbjct: 74 EVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGGRLLVCSE 133 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFE---VKEKDVAI 1035 G D G C D E L VKE F+ K ++ E V E A+ Sbjct: 134 GPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAV 193 Query: 1036 LEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE- 1094 L ++ E ADV W ++ P + + G + L + N + D G Y+C+ D+ Sbjct: 194 LSAVVSKEQADVTWLCPRQLAVPSE-RCQLRCDGRVHSLVLSNVAKEDAGVYTCLSPDDQ 252 Query: 1095 -----------------------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT 1131 +CT EL + + L + + +G EL Sbjct: 253 MQFDISVRGEHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSDVRARRGETVVLWCELC 312 Query: 1132 KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTV 1191 K V W KDG ++ ++ + G+++ L + +DAGEY CE + + A LTV Sbjct: 313 KAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTV 372 Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 + + + + ++V DA + E + VTW + +E+ + Sbjct: 373 QVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCH 432 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 +L +R C D T ST +L V+ E V R+ + DV L V+ Sbjct: 433 SLTVRGCQPSDAATVTANAEGLLSTARLSVQ--EAQVLFVRKLRDVVAEEQQDVCLEVEV 490 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + +W+ +++ +LTI+ V +D G Y+ Sbjct: 491 -SHEAAEVQWLKQGVLLQPGDKYLMRESGCRRTLTIRSVSPSDRGTYR 537 Score = 105 bits (252), Expect = 1e-20 Identities = 138/576 (23%), Positives = 235/576 (40%), Gaps = 59/576 (10%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIV----PDENISVAIESDMHMYCSVLKITNVKKFQE 705 D++LE +L + ++ W GE++ P E + + + L + + Sbjct: 3 DLVLEVQL-SHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRE----LPQSGAQPGDS 57 Query: 706 GTYTVVAVNREGEASLPIVLK-IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y A + S+ + + ++ KE Q PL+ V++G+SV L AQ+ +P Sbjct: 58 GCYVCDAASDRMVTSVEVPAQAVRIVNKEEAQ--SPLE---VQEGDSVTLVAQL--SPET 110 Query: 765 TIT-WCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 W K+ + + + L S+G S+TI K ++ D G + A G E + Sbjct: 111 AAAQWQKDGQMLLSGGRLLVCSEGPARSLTI-KQVELGDAGTFLCDA----GDDEVYFTL 165 Query: 821 TVEEPTEENAEPPLFINRFQE---ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE 877 V+E P LF+N+ +E + V E G+ L A V++ +TW ++ PSE Sbjct: 166 HVKEA------PVLFVNKQEEREKLLVLEGGSAVLSAVVSKEQA-DVTWLCPRQLAVPSE 218 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNS------AGKSSH--------GARVTI 923 DG LV++NV E D+G Y C++ + + + H GAR T Sbjct: 219 RCQLRCDGRVHSLVLSNVAKE-DAGVYTCLSPDDQMQFDISVRGEHWWLWGAQRGARGTC 277 Query: 924 DVEKVTF---VKHLQ--KSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQ 977 + V VK L+ G+TV+L C+ W + + + RE+ Sbjct: 278 TLMAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRV 337 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQET-STMLVVKETIPEFIRKLQDFEVKEKDVAIL 1036 +GR D G C D T +T+ V + E I +LQ V E D A Sbjct: 338 QGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATF 397 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 + ++ E V W+ DG + P + + + G L +R D + Sbjct: 398 KCMVSPEDVVVTWQLDGRPVVPSE-RLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLS 456 Query: 1097 TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI 1156 TA ++V E + +L++ + E+E++ A V+W K G +Q + + Sbjct: 457 TARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRE 516 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 G ++ L I D G Y CE + + L+VE Sbjct: 517 SGCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVE 552 Score = 90.2 bits (214), Expect = 5e-16 Identities = 105/464 (22%), Positives = 186/464 (40%), Gaps = 38/464 (8%) Query: 645 VDEGSDILLECRLVAIPEPDIA-WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V EG + L +L PE A W G+ ++ + V E L I V+ Sbjct: 94 VQEGDSVTLVAQLS--PETAAAQWQKDGQMLLSGGRLLVCSEGPARS----LTIKQVELG 147 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 GT+ A G+ + L +K E + ++V +G S +LSA VV + Sbjct: 148 DAGTFLCDA----GDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAVLSA-VVSKEQ 202 Query: 764 PTITW-CKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-- 818 +TW C P + + DG HS+ + K +D GVYT + + + + S Sbjct: 203 ADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAK-EDAGVYTCLSPDDQMQFDISVRG 261 Query: 819 ----VITVEEPTEEN-------AEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 + + AE + F+ ++ + T+ L + + + W Sbjct: 262 EHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSDVRARRGETVVLWCELCKAH-GDVVW 320 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ ++ P G LV++ V E D+G+Y C +++ A +T+ V Sbjct: 321 LKDGRVLEPDARREVRVQGRERSLVLSCVGPE-DAGEYCCESNDDRTL----ATLTVQVR 375 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTS-HTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 +V + +S EG +C S V W + + + + ++ + G Sbjct: 376 RVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLT 435 Query: 986 XXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA 1045 D + + ++ L V+E F+RKL+D +E+ LEVE++ E A Sbjct: 436 VRGCQPSDAATVTANAEGLLSTARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAA 495 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 +V W + G +++P +KY + G R L IR+ S D G Y C Sbjct: 496 EVQWLKQGVLLQP-GDKYLMRESGCRRTLTIRSVSPSDRGTYRC 538 Score = 89.8 bits (213), Expect = 7e-16 Identities = 65/249 (26%), Positives = 116/249 (46%), Gaps = 14/249 (5%) Query: 1035 ILEVEINSETADVVWERDGEIIKPKKNKYD---FEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 +LEV+++ +V W +DGE ++ + + RG +R+L D G Y C Sbjct: 5 VLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVC-- 62 Query: 1092 RDESCTAEVTVVELPPE---IITRLQNQ---KVNKGNKATFEIELTKGDALVRWFKDGSE 1145 D + VT VE+P + I+ + + Q +V +G+ T +L+ A +W KDG Sbjct: 63 -DAASDRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQM 121 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLP-- 1203 + + + +G + L I +L DAG + C+ G+ + L V+E + F + Sbjct: 122 LLSGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEER 181 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 E +LV A L+ + E DVTW + + +E+ L D + +L++ ++D Sbjct: 182 EKLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDA 241 Query: 1264 CEYTCVLLD 1272 YTC+ D Sbjct: 242 GVYTCLSPD 250 Score = 74.5 bits (175), Expect = 3e-11 Identities = 92/448 (20%), Positives = 163/448 (36%), Gaps = 45/448 (10%) Query: 946 VILECQTSHTVS-TKWYHNKKEISGMDHRE----IIQEGRXXXXXXXXXXXXDVGVIKCI 1000 ++LE Q SH KWY + +++ H I+ G D G C Sbjct: 4 LVLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVCD 63 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQ---DFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 T + V + K + EV+E D L +++ ETA W++DG+++ Sbjct: 64 AASDRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLL 123 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQK 1117 + G R L I+ + D G + C D+ + V E P + + + ++ Sbjct: 124 -SGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEERE 182 Query: 1118 ---VNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 V +G A ++K A V W S QL DG+ L + + +DAG Sbjct: 183 KLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAG 242 Query: 1175 EYSC------------------------EVGNSKCTAILTVEEPSINFTLRLPEFILVPA 1210 Y+C CT + E + F L + + Sbjct: 243 VYTCLSPDDQMQFDISVRGEHWWLWGAQRGARGTCTLMAVCAELQVKFLRGLSD-VRARR 301 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 L E+ DV W K V+E + + ++R+L++ +D EY C Sbjct: 302 GETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCES 361 Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND---EWIVNSKI 1327 D ++ L V+V I + + + G D T ++ P D W ++ + Sbjct: 362 NDDRTLATLTVQVRRVVEIIAELQ-SLMVLEGDDAT----FKCMVSPEDVVVTWQLDGRP 416 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + + + + SLT++ + +DA Sbjct: 417 VVPSERLQVARSGLCHSLTVRGCQPSDA 444 Score = 53.6 bits (123), Expect = 6e-05 Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 10/240 (4%) Query: 1127 EIELTKGDALVRWFKDGSEIQFSNH----IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 E++L+ V+W+KDG ++Q + H + + G ++L D+G Y C+ + Sbjct: 7 EVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVCDAAS 66 Query: 1183 SKCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE 1240 + + V ++ + + V L ++ ET W K ++ Sbjct: 67 DRMVTSVEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGG 126 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYR 1298 + + S+ R+L I++ D + C D + T +K V F K + E+ Sbjct: 127 RLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLV 186 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 ++ GS V V + Q + W+ ++ + + D + SL + V DAG+Y Sbjct: 187 LEGGSAVLSAVVSKE--QADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAGVY 244 Score = 40.3 bits (90), Expect = 0.57 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 2/78 (2%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q +FV KLR + V E +V + ++ W +Q +++P + M + Sbjct: 463 QEAQVLFVRKLRDVVAEEQQDVCLEVEVS-HEAAEVQWLKQGVLLQPGDKYLMR-ESGCR 520 Query: 566 ATLVIREVFPEDAGTFTC 583 TL IR V P D GT+ C Sbjct: 521 RTLTIRSVSPSDRGTYRC 538 Score = 36.3 bits (80), Expect = 9.2 Identities = 45/179 (25%), Positives = 73/179 (40%), Gaps = 18/179 (10%) Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDT----EKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 D L V++ +V WYK ++DT E+ +++ R L D Y C Sbjct: 3 DLVLEVQLSHAHGEVKWYKDGEKLQDTGHPGERVCIVARGALRELPQSGAQPGDSGCYVC 62 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREY---RIKRGSDVTLLVDYQAFPQPND-EWIVN 1324 + T VEV +IV+ E ++ G VTL+ Q P+ +W + Sbjct: 63 DAASDRMVTS--VEVPAQAVRIVNKEEAQSPLEVQEGDSVTLVA--QLSPETAAAQWQKD 118 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 +++ + + SLTIK+VE DAG + C D E+ T+ K +P Sbjct: 119 GQMLLSGGRLLVCSEGPARSLTIKQVELGDAGTFL------CDAGDDEVYFTLHVKEAP 171 >UniRef50_UPI0000ECB822 Cluster: Obscurin-like protein 1 precursor.; n=4; Gallus gallus|Rep: Obscurin-like protein 1 precursor. - Gallus gallus Length = 1173 Score = 128 bits (308), Expect = 2e-27 Identities = 159/722 (22%), Positives = 300/722 (41%), Gaps = 45/722 (6%) Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE----SVILSAQVVGNPR 763 + V AVN+ G + P+ + L+ VR GE SV LSA V G Sbjct: 431 FRVCAVNKHGRSD-PVEFPGCVHLVPAVHLERGLQDARVRDGEDARFSVELSASVQGEWF 489 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 T ++ + + + G HS+ +++ ++++ G +S SA++ V+ Sbjct: 490 LNGTRLQSEESGR-FSVQHCGTEHSL-LIRSARLRESGARVTFVASS---VRDSAILHVQ 544 Query: 824 EPTEENAEPPLFINRFQEI--TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 E P I+ +E T ++L +++R VP + WY++ E + E++ Sbjct: 545 EA------PVRIISSNEETPHTYMAGQRVELWCQLSRAEVP-VRWYKDGEEVEEGESLVL 597 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 +G LV+ + D+G++ C G S +T+ V V +++ T Sbjct: 598 EREGPRCRLVLPCAHPQ-DTGEFVC----DVGGDSAFYTITVAEPPVRIVGSNEEAPHTY 652 Query: 942 -EGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 G+ V L CQ S + +WY + +E+ + + ++G D G C Sbjct: 653 MAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLERKGPQCRLVLPCACPQDTGEFVC 712 Query: 1000 IVKDQE---TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 V T T+ + I Q E+ +LE E++ A V W +DGE + Sbjct: 713 DVGGDSVFYTITVAAPQAHIAPVPEAQQLQELLAGLPLLLECEVSPAGAPVRWLKDGEAM 772 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQ 1116 P ++ + G R+L+I D G Y+C D++ + VTV E P I++ + Sbjct: 773 VPSES-LGIQAEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIVSSNEET 831 Query: 1117 KVN--KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAG 1174 G + +L++ +A VRW+KDG E++ + L +G + +L + L D G Sbjct: 832 PHTYVAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQDTG 891 Query: 1175 EYSCEVGNSKCTAILTVEEPSINF--TLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 E+ C+ G++ + + V EP + R P + V L+ E+ V W ++ Sbjct: 892 EFVCDTGDAAVSYHVMVAEPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWARE 951 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD 1292 +E + L + R L+I + +Y C D T V+V + P +I++ Sbjct: 952 GVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYLCDAADDAVT--FTVQVSDPPVRILE 1009 Query: 1293 YEREYRIKRGSDV-TLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI--- 1347 + +R + L+++ Q + +W + + ++ H + D + +L I Sbjct: 1010 RDALPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEKDGQRRALVILGA 1069 Query: 1348 --KKVENTDAGIYKLRLENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEP 1404 V DAG+Y ++ D+ + V +++ + +LE D ++ C P Sbjct: 1070 TGSNVAKEDAGVYTCLSPDDQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFK-CMVSP 1128 Query: 1405 EN 1406 E+ Sbjct: 1129 ED 1130 Score = 104 bits (250), Expect = 2e-20 Identities = 155/717 (21%), Positives = 268/717 (37%), Gaps = 54/717 (7%) Query: 573 VFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGI 632 V P DAG + C A++ + A + L+VE S S+ T A G Sbjct: 29 VRPPDAGVYVCRARSGSKEALAAAVLLVEPRCSP--SDSTQPRRLRHACTDTWAPAPNGT 86 Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P + KA V G C + P+P+I W G+ + P I D Y Sbjct: 87 P-----RAKAFAVSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRR--HLIYEDREGY- 138 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 +LK+ + +G Y A N G+ + L++ + QV PL+ + V + E Sbjct: 139 FILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQV-AEHRLRFQV--PLEDVEVAEREDA 195 Query: 753 ILSAQVVGNPRPTITWCKNN--KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK-AEN 809 +L QV PT + ++ +P + G +TI + + D+G+Y + + Sbjct: 196 VLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVRRLTI-RDARTDDDGIYLCQMKDR 254 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 IAE S L + R +G TR V I+W RN Sbjct: 255 GRSIAEVSV-------------RGLIVKRLPRKLDVMEGENAAFCVETREAVEGISWTRN 301 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKV 928 + S G LV+ +V E D+G + S G+S +++ + V++ Sbjct: 302 GLQLHESPRAVLKSFGRTHLLVLVHVTRE-DAG----IICFSVGESLTSSQLRVKCVKRD 356 Query: 929 TFVKHLQKSYETEEGKTVILE-C---QTSHTVSTKWYHNKKEISGMDHREIIQ---EGRX 981 + TE+ +L C H + + ++E +G + + GR Sbjct: 357 PPGVPMAAQLSTEQSNAALLTWCPAPDVHHCPPSAYIVERREAAGGSWVQCLSTELPGRV 416 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVK---ETIP--EFIRKLQDFEVKEKDVAIL 1036 D C V S + +P R LQD V++ + A Sbjct: 417 QVLGDSVPREADYCFRVCAVNKHGRSDPVEFPGCVHLVPAVHLERGLQDARVRDGEDARF 476 Query: 1037 EVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEG-EYSCILRDE 1094 VE+ S + W +G ++ +++ ++ + G L IR+ + + G + + Sbjct: 477 SVEL-SASVQGEWFLNGTRLQSEESGRFSVQHCGTEHSLLIRSARLRESGARVTFVASSV 535 Query: 1095 SCTAEVTVVELPPEIITRLQN--QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI 1152 +A + V E P II+ + G + +L++ + VRW+KDG E++ + Sbjct: 536 RDSAILHVQEAPVRIISSNEETPHTYMAGQRVELWCQLSRAEVPVRWYKDGEEVEEGESL 595 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF-ILVPAN 1211 L +G + +L + D GE+ C+VG +TV EP + E A Sbjct: 596 VLEREGPRCRLVLPCAHPQDTGEFVCDVGGDSAFYTITVAEPPVRIVGSNEEAPHTYMAG 655 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 L ++ V WYK +E+ E L + L++ D E+ C Sbjct: 656 QRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLERKGPQCRLVLPCACPQDTGEFVC 712 Score = 77.8 bits (183), Expect = 3e-12 Identities = 94/414 (22%), Positives = 169/414 (40%), Gaps = 34/414 (8%) Query: 749 GESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKV-KDEGVYT 804 G ++L +V P + W K+ + P ++L +++G + I P V D G YT Sbjct: 747 GLPLLLECEVSPAGAP-VRWLKDGEAMVPSESLGIQAEGCWRRLHI--PTAVPSDSGTYT 803 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI--TVKEKGTIKLVARVTRNPVP 862 A G S V+TV E P ++ +E T ++L +++R P Sbjct: 804 CDA----GDDTVSFVVTVSEA------PVRIVSSNEETPHTYVAGQRVELWCQLSRAEAP 853 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + WY++ E + E++ +G LV+ + D+G++ C ++A S+ V Sbjct: 854 -VRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQ-DTGEFVCDTGDAA--VSYHVMVA 909 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 K+ + + G+TV L C+ S W + + +EG Sbjct: 910 EPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAH 969 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK--LQDFE-VKEKDVAILEV 1038 G C D + + V + + + L + + +LEV Sbjct: 970 RRLLIPAARAEHAGKYLCDAADDAVTFTVQVSDPPVRILERDALPTCRRCRAMEDLVLEV 1029 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI-----RNTSVHDEGEYSCILRD 1093 +++ +V W +DGE ++ + EK G R L I N + D G Y+C+ D Sbjct: 1030 QLSHAHGEVKWYKDGEKLQDTGH-VRLEKDGQRRALVILGATGSNVAKEDAGVYTCLSPD 1088 Query: 1094 ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI 1146 + +++V V EII LQ+ V +G+ ATF+ ++ D +V W DG + Sbjct: 1089 DQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPV 1142 Score = 72.5 bits (170), Expect = 1e-10 Identities = 97/432 (22%), Positives = 170/432 (39%), Gaps = 36/432 (8%) Query: 640 PKAQYVDE---GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 P+AQ + E G +LLEC + P + WL GE +VP E++ + E L Sbjct: 736 PEAQQLQELLAGLPLLLECEVSPAGAP-VRWLKDGEAMVPSESLGIQAEGCWRR----LH 790 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSA 756 I GTYT A G+ ++ V+ + E V G+ V L Sbjct: 791 IPTAVPSDSGTYTCDA----GDDTVSFVVTVSEAPVRIVSSNEETPHTYVA-GQRVELWC 845 Query: 757 QVVGNPRPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 Q+ P + W K+ + V+ +L + +G + +L +++D G + G Sbjct: 846 QLSRAEAP-VRWYKDGEEVEEGESLVLEREGPRCRL-VLPCARLQDTGEFVCDT----GD 899 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 A S + V EP + +P + V T+ L ++R P + W R + Sbjct: 900 AAVSYHVMVAEPPVKILQPQ---RPPPVVKVSPGETVTLSCELSRPDAP-VCWAREGVRL 955 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + +G + L+I +E +G Y C A++ A + +V+ ++ Sbjct: 956 EAGGSWVLEEEGAHRRLLIPAARAE-HAGKYLCDAADDA--VTFTVQVSDPPVRILERDA 1012 Query: 934 LQKSYETEEGKTVILECQTSHTVS-TKWYHNKKEISGMDHREIIQEGRXXX-----XXXX 987 L + ++LE Q SH KWY + +++ H + ++G+ Sbjct: 1013 LPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEKDGQRRALVILGATGS 1072 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVK-ETIPEFIRKLQDFEVKEKDVAILEVEINSETAD 1046 D GV C+ D + + V+ + E I +LQ V E D A + ++ E Sbjct: 1073 NVAKEDAGVYTCLSPDDQMQFDISVRVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVV 1132 Query: 1047 VVWERDGEIIKP 1058 V W+ DG + P Sbjct: 1133 VTWQLDGRPVVP 1144 Score = 71.7 bits (168), Expect = 2e-10 Identities = 102/513 (19%), Positives = 192/513 (37%), Gaps = 32/513 (6%) Query: 1118 VNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK-LKIYDCDLDDAGE 1175 V+ G A F +T K + W KDG + + D + LK+ C D G Sbjct: 94 VSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGL 153 Query: 1176 YSCEVGNSKCTAI----LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 Y C N+ + L V E + F + L E + V DA L ++P ++ W+ Sbjct: 154 YVCTASNTAGQTLSAVQLQVAEHRLRFQVPL-EDVEVAEREDAVLECQVPLGSIPTAWFL 212 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVE--VVEFPP 1288 + ++ + K+ + R L IR DD Y C + D +S ++ V +V+ P Sbjct: 213 EDRELQPSHKYVMEECGVVRRLTIRDARTDDDGIYLCQMKDRGRSIAEVSVRGLIVKRLP 272 Query: 1289 KIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK 1348 + +D + G + V+ + + W N + + ++ L + Sbjct: 273 RKLD------VMEGENAAFCVETREAVE-GISWTRNGLQLHESPRAVLKSFGRTHLLVLV 325 Query: 1349 KVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG 1408 V DAGI + + + + + D P P + S++ + W + Sbjct: 326 HVTREDAGIICFSVGESLTSSQLRVKCVKRDPPGVPMAAQLSTEQSNAALLTWCPAPDVH 385 Query: 1409 NSTIIYYVVEYQEIDTTEWI---SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + Y+VE +E W+ S + + Q ++ + Y FR AVN+ SD Sbjct: 386 HCPPSAYIVERREAAGGSWVQCLSTELPGRVQVLGDSVPREADYCFRVCAVNKHGRSDPV 445 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 E ++ + E+ L++ ED + Q + W+ +G +L++ Sbjct: 446 EFPGCVHLVPAVHL-----ERGLQDARVRDGEDARFSVELSASVQGE--WFLNGTRLQSE 498 Query: 1526 KA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV-ITISNEDIK 1581 ++ + ++ V S ++ +Q+ PV I SNE+ Sbjct: 499 ESGRFSVQHCGTEHSLLIRSARLRESGARVTFVASSVRDSAILHVQEAPVRIISSNEETP 558 Query: 1582 QKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 + G + + P V WYK+G ++E Sbjct: 559 HTYMAGQRVELWCQLSRAEVP-VRWYKDGEEVE 590 Score = 63.7 bits (148), Expect = 5e-08 Identities = 51/247 (20%), Positives = 107/247 (43%), Gaps = 6/247 (2%) Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVT 1101 +++W++DG+ + P + +E R L + D+G Y C + + ++ Sbjct: 113 EIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQ 172 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 V E L++ +V + A E ++ G WF + E+Q S+ + G + Sbjct: 173 VAEHRLRFQVPLEDVEVAEREDAVLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVR 232 Query: 1162 KLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP 1221 +L I D DD G Y C++ + +I V + RLP + V +A VE Sbjct: 233 RLTIRDARTDDDGIYLCQM-KDRGRSIAEVSVRGL-IVKRLPRKLDVMEGENAAFCVETR 290 Query: 1222 DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 + ++W + + ++ + L S + L++ T +D + ++ ++++L+V Sbjct: 291 EAVEGISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRV 350 Query: 1282 EVVEFPP 1288 + V+ P Sbjct: 351 KCVKRDP 357 Score = 51.6 bits (118), Expect = 2e-04 Identities = 24/77 (31%), Positives = 35/77 (45%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +F C V G P+P+I W + + P + +Y D + L + P D G + C Sbjct: 97 GKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVC 156 Query: 584 VAKNAAGFASSTTELIV 600 A N AG S +L V Sbjct: 157 TASNTAGQTLSAVQLQV 173 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P PE+IW K+G + + + I +E ++++ + Y ASNTAG + Sbjct: 106 VTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQT 165 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREIS-RESVTIEWKPPL 1691 V L+V + + + P+ E++ RE +E + PL Sbjct: 166 LSAVQLQVAEHRLRFQVPLEDVEVAEREDAVLECQVPL 203 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/152 (19%), Positives = 58/152 (38%), Gaps = 2/152 (1%) Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 + W +NG +L + + +T ++ + + R + + +S + V Sbjct: 296 ISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRVKCVKR 355 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 D P P + E S ++ + W P D + Y +E+ E W++ + Sbjct: 356 DPPGVPMAAQLSTEQSNAAL-LTWCPAPDVHHCPPSAYIVERREAAGGSWVQCLSTELPG 414 Query: 1724 ETYCI-QKLNENCEYMFRVIAQNPVGFSEALE 1754 + + +Y FRV A N G S+ +E Sbjct: 415 RVQVLGDSVPREADYCFRVCAVNKHGRSDPVE 446 Score = 38.7 bits (86), Expect = 1.7 Identities = 39/195 (20%), Positives = 75/195 (38%), Gaps = 3/195 (1%) Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 +T + + E ++ + + + T + +EL C P V WY+DG++++ Sbjct: 809 DTVSFVVTVSEAPVRIVSSNEETPH-TYVAGQRVELWCQLSRAEAP-VRWYKDGEEVEEG 866 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK 1585 ++ R D G+ S V + + PV + + K Sbjct: 867 ESLVLEREGPRCRLVLPCARLQDTGEFVCDTGDAAVSYHVMVAEPPVKILQPQRPPPVVK 926 Query: 1586 VGDEWLVTAVIE-GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 V VT E P V W + G +LE + + + + I + H+ KY Sbjct: 927 VSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYL 986 Query: 1645 IEASNTAGTSSVEVT 1659 +A++ A T +V+V+ Sbjct: 987 CDAADDAVTFTVQVS 1001 >UniRef50_Q4RH47 Cluster: Chromosome undetermined SCAF15069, whole genome shotgun sequence; n=3; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF15069, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1485 Score = 128 bits (308), Expect = 2e-27 Identities = 103/401 (25%), Positives = 183/401 (45%), Gaps = 22/401 (5%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P +P V++ E ++ V + WKPP+ G E Y IEK + W +V + V++ Sbjct: 475 PGEPTD-VVVTEATKSYVVLAWKPPVQRGH-EGVMYYIEKCVSGTDSWQRV-NTGMPVKS 531 Query: 1726 --YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + + L E Y FRV N G EA + + I + LD+P+ N Sbjct: 532 PRFAMFDLAEGKTYSFRVRCCNSAGVGEASVSTGEITVGDVLDLPAAPGNPVVIRNT-NT 590 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXARI--QKLSINTTYQFRI 1839 SV +TW S+ ++ Y +E Q G W R L+ Y FR+ Sbjct: 591 SVVVTWGASKDV--KHLVGYYIECSQTGTDIWMACNNKPVKETRFVCHGLTNGANYVFRV 648 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N G S + + + ++ P +P + E+ + L WT P ++GG+ + Sbjct: 649 KAVNAAGYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMVLGWTAPANDGGATVRG 708 Query: 1900 YIIEFKTVKGK---SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 Y ++++TVKG W ++ + + EN+KE F++ A N G+S + + Sbjct: 709 YFVDYRTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGSVPSA 768 Query: 1957 VRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT--KTM 2012 V K T+ + P AP+++R+ V V+ W P + G P+ GY + +++ + + Sbjct: 769 VLECKEWTI-TLPGAPVDLRVLEVRDTSVVLLWEPPAFCGRTPVNGYYVDLKEASAGEDG 827 Query: 2013 WMEVGKVDVNTLKF-NIRDLSENHTYMIRIYARNEIGLSEP 2052 W V + VN +K+ ++ L + +Y+ R+ A+N G+ +P Sbjct: 828 WKAVHE-KVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKP 867 Score = 97.5 bits (232), Expect = 4e-18 Identities = 80/335 (23%), Positives = 134/335 (40%), Gaps = 20/335 (5%) Query: 1634 ELKRSHSSKYTIEASNTAGT-----SSVEVTL-KVYDKPSKPEGPVIMREISRESVTIEW 1687 +L + + + N+AG S+ E+T+ V D P+ P PV++R + SV + W Sbjct: 538 DLAEGKTYSFRVRCCNSAGVGEASVSTGEITVGDVLDLPAAPGNPVVIRN-TNTSVVVTW 596 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 D L Y IE + + W+ + + L Y+FRV A N Sbjct: 597 GASKDVK--HLVGYYIECSQTGTDIWMACNNKPVKETRFVCHGLTNGANYVFRVKAVNAA 654 Query: 1748 GFSEAL-ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI----IDY 1802 G+S + +SE +V+K A+ VP + + V + W +GG+ + +DY Sbjct: 655 GYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMV-LGWTAPANDGGATVRGYFVDY 713 Query: 1803 KVEIKQEGKKWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 + KW + + L N Y+F++ A N G S + Sbjct: 714 RTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGSVPSAVLECK 773 Query: 1861 K-TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG--KSWTKIVT 1917 + T+T P P + V E SV L W P G +P+ Y ++ K W + Sbjct: 774 EWTITLPGAPVDLRVLEVRDTSVVLLWEPPAFCGRTPVNGYYVDLKEASAGEDGWKAVHE 833 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 V ++ +K +FR+ A+N GV P+ Sbjct: 834 KVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKPS 868 Score = 70.1 bits (164), Expect = 6e-10 Identities = 56/214 (26%), Positives = 95/214 (44%), Gaps = 20/214 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F KP+ Q V EG + L C + P+P IAW +K ++ + ++ Sbjct: 75 PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAW-YKNNVLIDAKAHPEKYTAESTYNM 133 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP----------PQVIEPLK 742 L+I N Y+V A+N +GEAS + +K +++ + + + Sbjct: 134 HSLEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193 Query: 743 SMIVRQGESVILSAQV-----VGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKP 794 +GE+V L V V N +P + W +++ KP K + T G+ +T++ Sbjct: 194 VAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLVHL 253 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 K +DEG+YTL+ G SA + V + E Sbjct: 254 NK-EDEGMYTLRVNTKSGYDSYSAYVFVRDADVE 286 Score = 67.7 bits (158), Expect = 3e-09 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 20/208 (9%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDT----H 787 PP+ I + V +G+++ L V G P+P I W KNN + KA P K ++ H Sbjct: 75 PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMH 134 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN--AEPPL-----FINRFQ 840 S+ I K D Y++ A N +G A A I V+ E+ AE + ++F+ Sbjct: 135 SLEI-KNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193 Query: 841 EITVKEKGTIKLVARV-----TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 E T+ L V +N P + WYR++ + PS+ + ++ GE L + ++ Sbjct: 194 VAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLVHL 253 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTI 923 + E D G Y + +G S+ A V + Sbjct: 254 NKE-DEGMYTLRVNTKSGYDSYSAYVFV 280 Score = 51.2 bits (117), Expect = 3e-04 Identities = 49/240 (20%), Positives = 95/240 (39%), Gaps = 28/240 (11%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--NVAT 567 P F+ K R + +G T+ C V G+P+P+I W++ +I + Y + N+ + Sbjct: 76 PEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMHS 135 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 L I+ D ++ A N G AS ++V+ D A+ Sbjct: 136 LEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQED----------------AFCAE 179 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-----EPDIAWLFKGEEIVPDENISV 682 T + K + + EG + L C ++ P +P++ W + P + + Sbjct: 180 HGVTFLTTITDKFEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQT 239 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPL 741 + ++L + ++ K EG YT+ + G S + ++ + E V + PL Sbjct: 240 HWSGER----AILTLVHLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVEVEGVPVAPL 295 Score = 48.8 bits (111), Expect = 0.002 Identities = 61/318 (19%), Positives = 121/318 (38%), Gaps = 40/318 (12%) Query: 1426 EWISVKNI----TKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQ 1480 ++++++N+ + ++ K + R R A E+ E E+ + + + Sbjct: 14 QYVAMRNLFVREAREAVDVKVQKKTRTTRMRESAERVELSKDGLDEWVEFRRKMNPDSLT 73 Query: 1481 SPT--VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-----DGK---KLKTAKATYE 1530 P + KP + T + + L C G P+PK+ WY+ D K + TA++TY Sbjct: 74 HPPEFIIKP-RGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTY- 131 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED-IKQKHKVGDE 1589 N Y A N GE + +++ E + + D+ Sbjct: 132 NMHSLEIKNCSFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDK 191 Query: 1590 WLVTAVIEG----------IPP------PEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 + V EG + P PEV+WY++ L+ K + +++ + Sbjct: 192 FEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYRDSVPLKPSKWVQTHWSGERAILTLV 251 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG------PVIMREISRESVTIEW 1687 L + YT+ + +G S + V D + EG V + +++ V + W Sbjct: 252 HLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVEVEGVPVAPLDVCCHDANKDYVVVTW 311 Query: 1688 KPPLDDGGLELTKYAIEK 1705 K P +G + Y +++ Sbjct: 312 KQPAVEGSSSILGYYVDR 329 Score = 46.4 bits (105), Expect = 0.009 Identities = 24/95 (25%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Query: 1377 ILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--IT 1434 +LD P+ PG P ++ ++S+ + W ++ + ++ Y +E + T W++ N + Sbjct: 572 VLDLPAAPGNPVVIRNTNTSVVVTWGASKDVKH--LVGYYIECSQTGTDIWMACNNKPVK 629 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 +T+ L ++Y FR AVN S +S +E Sbjct: 630 ETRFVCHGLTNGANYVFRVKAVNAAGYSPSSPDSE 664 Score = 46.0 bits (104), Expect = 0.011 Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650 +T + G P PEV W KN +L +D Y +T + K + I I + + S KY + N Sbjct: 1407 LTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGKYALLVKNK 1466 Query: 1651 AGTSSVEVTLKVYDKPSKPE 1670 GT + T+ VY+ P + E Sbjct: 1467 YGTEAGAFTVSVYN-PEEEE 1485 Score = 45.6 bits (103), Expect = 0.015 Identities = 73/323 (22%), Positives = 124/323 (38%), Gaps = 30/323 (9%) Query: 1357 IYKLRLENNCGHADVEMN---VTILDKPSPPGKPN---ILEIDSSSINICWDEPENTGNS 1410 +++++ N G++ + V + S PGKP +LE + + W P N G + Sbjct: 645 VFRVKAVNAAGYSPSSPDSEAVVVKAAISVPGKPTGVTLLEAVKDRMVLGWTAPANDGGA 704 Query: 1411 TIIYYVVEYQEID---TTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 T+ Y V+Y+ + +W + + +T T +NLK N Y F+ A+N +S S Sbjct: 705 TVRGYFVDYRTVKGDVVGKWHEMNHQALTTTSYKAENLKENVFYEFQVRAMNMAGLSKGS 764 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLK 1523 + + KE I P L+ + + L F G P +Y D K+ Sbjct: 765 VPSAVLE-CKEWTITLPGAPVDLRVLEVRDTSVVLLWEPPAFCG-RTPVNGYYVDLKEAS 822 Query: 1524 TA----KATYE--NRXXXXXXXXXX-XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 KA +E NR ++ A N G + S +G PV+ + Sbjct: 823 AGEDGWKAVHEKVNRVKYLKVKGLKPDTSYVFRVRAQNLTGVGKPSATLG----PVLAQT 878 Query: 1577 NEDIKQKH-KVGDEWLVTAVI---EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 K+ + V D+ +++ V E E IW KN + + I + S Sbjct: 879 RAGTKEIYVDVDDDGVISMVFECSEMTESSEFIWSKNYQAITDTSRVTIVNERGRSRAIF 938 Query: 1633 KELKRSHSSKYTIEASNTAGTSS 1655 ++ A+NT G SS Sbjct: 939 NNPSLEDLGTFSCVATNTDGMSS 961 Score = 44.8 bits (101), Expect = 0.026 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 6/103 (5%) Query: 731 EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGD 785 E+ +VI L ++ +++G+S+ L+ V G+P P ++W KN K + + T G Sbjct: 1383 ERNRARVIGGLPDVVAIQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGK 1442 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 SITI + D G Y L +N G + ++V P EE Sbjct: 1443 FASITIAAVTEA-DSGKYALLVKNKYGTEAGAFTVSVYNPEEE 1484 Score = 43.2 bits (97), Expect = 0.081 Identities = 49/222 (22%), Positives = 81/222 (36%), Gaps = 30/222 (13%) Query: 1227 VTWYKKKSVIE---DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 + WYK +I+ EK+T S +L I+ C+ D +Y+ L+ K + Sbjct: 107 IAWYKNNVLIDAKAHPEKYTAESTYNMHSLEIKNCSFTDTAQYSVSALNVKGEASYVATI 166 Query: 1284 V---------------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFP-----QPNDEWIV 1323 V F I D G V+L +P QP W Sbjct: 167 VVKRYQEDAFCAEHGVTFLTTITDKFEVAFGTEGETVSLGCTVIVYPTVKNYQPEVVWYR 226 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--- 1380 +S +K K + + A LT+ + D G+Y LR+ G+ V + D Sbjct: 227 DSVPLKPSKWVQTHWSGERAILTLVHLNKEDEGMYTLRVNTKSGYDSYSAYVFVRDADVE 286 Query: 1381 ----PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 P P + + + + W +P G+S+I+ Y V+ Sbjct: 287 VEGVPVAPLDVCCHDANKDYVVVTWKQPAVEGSSSILGYYVD 328 Score = 41.9 bits (94), Expect = 0.19 Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS---ETITQNFDGENI 888 PP FI + + TV E T+ L V P P I WY+NN +I E T Sbjct: 75 PPEFIIKPRGQTVWEGQTLSLHCTVAGWPKPKIAWYKNNVLIDAKAHPEKYTAESTYNMH 134 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID---------VEKVTFVKHLQKSYE 939 L I N S D+ Y A N G++S+ A + + VTF+ + +E Sbjct: 135 SLEIKNC-SFTDTAQYSVSALNVKGEASYVATIVVKRYQEDAFCAEHGVTFLTTITDKFE 193 Query: 940 T---EEGKTVILEC 950 EG+TV L C Sbjct: 194 VAFGTEGETVSLGC 207 Score = 37.9 bits (84), Expect = 3.0 Identities = 36/152 (23%), Positives = 65/152 (42%), Gaps = 11/152 (7%) Query: 789 ITILKPKKVKDEG--VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 + LK K +K + V+ ++A+N G+ + SA + ++++ V + Sbjct: 838 VKYLKVKGLKPDTSYVFRVRAQNLTGVGKPSATLGPVLAQTRAGTKEIYVD------VDD 891 Query: 847 KGTIKLVARVTRNPVPS-ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 G I +V + S W +N + I+ + +T + + N E D G + Sbjct: 892 DGVISMVFECSEMTESSEFIWSKNYQAITDTSRVTIVNERGRSRAIFNNPSLE-DLGTFS 950 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 CVA+N+ G SS ++FV HLQ S Sbjct: 951 CVATNTDGMSSSYTLTEEGKSHLSFV-HLQNS 981 Score = 37.1 bits (82), Expect = 5.3 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRN-NEIISPSETITQNFDGENIELVITNVDSEID 900 + ++E ++ L V +PVP ++W +N E++S G+ + I V +E D Sbjct: 1397 VAIQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAV-TEAD 1455 Query: 901 SGDYKCVASNSAGKSSHGARVTI 923 SG Y + N G + V++ Sbjct: 1456 SGKYALLVKNKYGTEAGAFTVSV 1478 Score = 36.3 bits (80), Expect = 9.2 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGI 1357 I+ G + L + P P W N K + H K + + K AS+TI V D+G Sbjct: 1399 IQEGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGK 1458 Query: 1358 YKLRLENNCG 1367 Y L ++N G Sbjct: 1459 YALLVKNKYG 1468 Score = 36.3 bits (80), Expect = 9.2 Identities = 17/81 (20%), Positives = 36/81 (44%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G ++ V G P P+++W + + +++ Y+ A++ I V D+G + Sbjct: 1401 EGKSLNLTGNVWGDPVPEVSWTKNEKELLSDDHYKLTYEHGKFASITIAAVTEADSGKYA 1460 Query: 583 CVAKNAAGFASSTTELIVEAP 603 + KN G + + V P Sbjct: 1461 LLVKNKYGTEAGAFTVSVYNP 1481 >UniRef50_UPI000065D2BB Cluster: Homolog of Homo sapiens "Palladin; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Palladin - Takifugu rubripes Length = 986 Score = 127 bits (307), Expect = 3e-27 Identities = 97/364 (26%), Positives = 165/364 (45%), Gaps = 23/364 (6%) Query: 478 NNYTQYLQKKLNEKIDKLPVFEKPTS---EEQSM----APIFVEKLRPKHTPDGSTVQFE 530 +++ Q L ++ ++++ PV E +E S AP F KL+ +G V F Sbjct: 591 SSFEQRLISEIEFRLERSPVEESDDDVQHDEDSAGRGAAPSFDRKLKHYKVFEGMPVTFS 650 Query: 531 CQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 C+V G P+P++ WF+ I K S+ +++ D D +L +D G +T +A N Sbjct: 651 CKVNGDPKPKVYWFKDGKQISKRSEHYRISRDADGTCSLHTVAASLDDDGNYTIMASNPE 710 Query: 590 GFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQY 644 G S T ++V+A S+ ++ D + I P F + P Sbjct: 711 GRVSCTGRMMVQAVNQRGRSKRSMPGHMRRSRSRDSGDENDNIQERHFRPHFLQAPGDLI 770 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNVKKF 703 V EG ++C++ +P PD+ W G+ I PD + + E+ +H L I V Sbjct: 771 VQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHS----LVIEPVTSR 826 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 G YT +A NR G+ S + L + E + P +E L++ V +G V L +V G P Sbjct: 827 DAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLECRVSGVP 886 Query: 763 RPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P I W + N+ + + D + I++P +D G YT+ A+N GI ++A Sbjct: 887 YPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKNEAGIVSSTA 946 Query: 819 VITV 822 + + Sbjct: 947 RLDI 950 Score = 82.6 bits (195), Expect = 1e-13 Identities = 41/111 (36%), Positives = 63/111 (56%), Gaps = 2/111 (1%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 P+S+E P F++KL+ + +GS + ECQV G P+P + WF + + S D Q+ Sbjct: 5 PSSQEPLSPPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQI-S 63 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610 D + TLVI E F +D G +TC+A N G +++ E+ +E A SD E Sbjct: 64 SDGVLHTLVISEAFEDDTGRYTCIASNCLGADNTSAEVYIEGASSSDSDGE 114 Score = 81.8 bits (193), Expect = 2e-13 Identities = 80/330 (24%), Positives = 146/330 (44%), Gaps = 37/330 (11%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESD-- 687 G P+F +K K V EG + C++ P+P + W G++I E+ ++ ++D Sbjct: 627 GAAPSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQISKRSEHYRISRDADGT 686 Query: 688 --MHMYCSVL----KITNVKKFQEGTYT------VVAVNREGEA--SLPIVLKIK----T 729 +H + L T + EG + V AVN+ G + S+P ++ + Sbjct: 687 CSLHTVAASLDDDGNYTIMASNPEGRVSCTGRMMVQAVNQRGRSKRSMPGHMRRSRSRDS 746 Query: 730 GEKEP--------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK 781 G++ P ++ +IV++G + +V G P P + W N + ++ Sbjct: 747 GDENDNIQERHFRPHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAH 806 Query: 782 S----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 + HS+ +++P +D G+YT A N G + S + + +E + P F+ Sbjct: 807 KMLVRENGVHSL-VIEPVTSRDAGIYTCIASNRAG--QNSFNLELIVAAKEMHKVPTFME 863 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP-SETITQNFDGENIELVITNVD 896 + Q +V E ++L RV+ P P I W R NE ++ ++ I+ + D +I Sbjct: 864 KLQNTSVAEGHPVRLECRVSGVPYPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPA 923 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + D+G Y A N AG S AR+ I + Sbjct: 924 LKEDAGWYTVSAKNEAGIVSSTARLDIHTQ 953 Score = 63.3 bits (147), Expect = 7e-08 Identities = 38/101 (37%), Positives = 49/101 (48%), Gaps = 8/101 (7%) Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DDDNVATL 568 L+ +G V E +V G P Q+ WFRQ I S DF++ + + + TL Sbjct: 172 LQDVQASEGQVVVLESRVRGSPPLQVRWFRQGEEILDSPDFRILQKKPRSAAESEEICTL 231 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 VI E FPED G F C N G +ST L V A S HG+ Sbjct: 232 VIAEAFPEDGGLFCCTVSNPYGSKNSTAHLAVTAGES-HGN 271 Score = 56.8 bits (131), Expect = 6e-06 Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 1/99 (1%) Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 ++E PP F+ + + V E I L +VT NP P + W+ + S I + DG Sbjct: 7 SQEPLSPPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDG 66 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 LVI+ E D+G Y C+ASN G + A V I+ Sbjct: 67 VLHTLVISEA-FEDDTGRYTCIASNCLGADNTSAEVYIE 104 Score = 55.2 bits (127), Expect = 2e-05 Identities = 34/125 (27%), Positives = 60/125 (48%), Gaps = 5/125 (4%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P F+ ++ V+E ++ +V+ P P + W N + I P + ++ Sbjct: 760 PHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLV 819 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKV-TFVKHLQKSYETEEGKTVIL 948 + D+G Y C+ASN AG++S + + ++ KV TF++ LQ + EG V L Sbjct: 820 IEPVTSRDAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNT-SVAEGHPVRL 878 Query: 949 ECQTS 953 EC+ S Sbjct: 879 ECRVS 883 Score = 54.8 bits (126), Expect = 2e-05 Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 4/101 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSIT 790 PP ++ LKS V +G + L QV GNP+P + W + + P SDG H++ Sbjct: 13 PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLHTLV 72 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 I + + D G YT A N G TSA + +E + +++ Sbjct: 73 ISEAFE-DDTGRYTCIASNCLGADNTSAEVYIEGASSSDSD 112 Score = 53.6 bits (123), Expect = 6e-05 Identities = 28/78 (35%), Positives = 43/78 (55%), Gaps = 1/78 (1%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP + +L++Q+V +G+ E ++T LVRWF +G E+ S IQ++ DG L Sbjct: 13 PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLHTLV 72 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 I + DD G Y+C N Sbjct: 73 ISEAFEDDTGRYTCIASN 90 Score = 52.8 bits (121), Expect = 1e-04 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F +K K+Q V EGS I LEC++ P+P + W +G E+ +I ++ + +H Sbjct: 13 PPCFLQKLKSQEVAEGSPIHLECQVTGNPQPLVRWFCEGRELHNSPDIQISSDGVLH--- 69 Query: 693 SVLKITNVKKFQEGTYTVVAVN 714 L I+ + G YT +A N Sbjct: 70 -TLVISEAFEDDTGRYTCIASN 90 Score = 41.9 bits (94), Expect = 0.19 Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEK-TSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G+P P++IW NG + D + + +E + I+ + + YT ASN AG + Sbjct: 783 VSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLVIEPVTSRDAGIYTCIASNRAGQN 842 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESV 1683 S + L V K + P M ++ SV Sbjct: 843 SFNLELIVAAK-EMHKVPTFMEKLQNTSV 870 Score = 41.5 bits (93), Expect = 0.25 Identities = 39/178 (21%), Positives = 76/178 (42%), Gaps = 12/178 (6%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D V+E + ++ +++ T D++W+ +G+ I+P + + L Sbjct: 760 PHFLQAPGDLIVQEGRLCRMDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLV 819 Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y+CI + S E+ V + P + +LQN V +G+ E Sbjct: 820 IEPVTSRDAGIYTCIASNRAGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLE 879 Query: 1128 IELTKGD-ALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDL-DDAGEYSCEVGN 1182 ++ + W ++ + Q ++ I + D I L +DAG Y+ N Sbjct: 880 CRVSGVPYPQIFWKRENESLTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKN 937 Score = 37.9 bits (84), Expect = 3.0 Identities = 28/115 (24%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + E+ + +E + P F + + V E + +V +P P + W+++ + Sbjct: 610 VEESDDDVQHDEDSAGRGAAPSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQ 669 Query: 873 ISP-SE--TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 IS SE I+++ DG ++ V ++D D G+Y +ASN G+ S R+ + Sbjct: 670 ISKRSEHYRISRDADGTCSLHTVAASLD---DDGNYTIMASNPEGRVSCTGRMMV 721 Score = 37.9 bits (84), Expect = 3.0 Identities = 34/182 (18%), Positives = 67/182 (36%), Gaps = 10/182 (5%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXXXXXYKCIAFND 1555 + C G+P P + W +G+ ++ A EN Y CIA N Sbjct: 779 MDCKVSGLPTPDLIWQLNGQTIRPDSAHKMLVRENGVHSLVIEPVTSRDAGIYTCIASNR 838 Query: 1556 HGE--VETSCVVGIQQKPVITISNEDIKQKHKV-GDEWLVTAVIEGIPPPEVIWYKNGNK 1612 G+ +V ++ + E ++ G + + G+P P++ W + Sbjct: 839 AGQNSFNLELIVAAKEMHKVPTFMEKLQNTSVAEGHPVRLECRVSGVPYPQIFWKRENES 898 Query: 1613 LENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 L + + ++ + I+ + + YT+ A N AG S L ++ + +P Sbjct: 899 LTQNTDRISMHQDNCGYLCMIIQPALKEDAGWYTVSAKNEAGIVSSTARLDIHTQWQQPN 958 Query: 1671 GP 1672 P Sbjct: 959 LP 960 Score = 37.5 bits (83), Expect = 4.0 Identities = 14/49 (28%), Positives = 26/49 (53%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY 1529 +P+ ++ LK+ + +C G P+PKV W++DGK++ Y Sbjct: 629 APSFDRKLKHYKVFEGMPVTFSCKVNGDPKPKVYWFKDGKQISKRSEHY 677 Score = 36.3 bits (80), Expect = 9.2 Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 9/94 (9%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQ-K 1162 P +L++ KV +G TF ++ GD V WFKDG +I + S H +++ D Sbjct: 630 PSFDRKLKHYKVFEGMPVTFSCKVN-GDPKPKVYWFKDGKQISKRSEHYRISRDADGTCS 688 Query: 1163 LKIYDCDLDDAGEYSCEVGNSK----CTAILTVE 1192 L LDD G Y+ N + CT + V+ Sbjct: 689 LHTVAASLDDDGNYTIMASNPEGRVSCTGRMMVQ 722 >UniRef50_UPI000065E224 Cluster: eEF1A2 binding protein; n=2; Takifugu rubripes|Rep: eEF1A2 binding protein - Takifugu rubripes Length = 788 Score = 127 bits (306), Expect = 4e-27 Identities = 95/397 (23%), Positives = 156/397 (39%), Gaps = 15/397 (3%) Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K + G + G P + WY+ G +L D + S + + +R + + Sbjct: 103 KVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNNVKVEKCRSQSRLLLSRCQRKDTGE 162 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 I+ N G + L V DKP+ P GP E S V +W+PP DDGG +T Y Sbjct: 163 IKIKLKNQHGVTEAISQLIVLDKPTPPLGPAETTESSATCVEFKWRPPKDDGGSPVTHYL 222 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 +E+ + N W K+ ++ V + + +Y +R+ A G SE +E++ + T Sbjct: 223 MERQQVGRNTWKKLGEIP-GVPRHRDTDVEHGRKYCYRIWAVTAEGTSEMMETDEMQAGT 281 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822 L P D + + I W GGS I+ Y VE +++G Sbjct: 282 -LAFPGPPAPPAVVSAFD-DCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTINATDD 339 Query: 1823 XARIQKLSINTT-----YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 + +K ++ Y+FR+ A N G + + + PP + VSE+ Sbjct: 340 LIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSSPSEFVFARDPKKPPGKVVGLKVSET 399 Query: 1878 TSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE 1935 + L WT+PE G Y I+ + W++ T + +K D Sbjct: 400 SYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCIEWSRCNTSPLITTSFSVRGLKHMDM 459 Query: 1936 IIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 R++A N G P E L+K+ T P P Sbjct: 460 YWARVTATNDGGDGPPEE-----LQKYITAMPRPVRP 491 Score = 101 bits (242), Expect = 2e-19 Identities = 111/472 (23%), Positives = 177/472 (37%), Gaps = 25/472 (5%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 E +W+K G K+ D ++ I + + I + K HS KY A E + V Sbjct: 29 EGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVADG----RKTEAMINV 84 Query: 1663 YDKPS-KPEGPVIMRE--ISRESVTIEWKPP-LDDGGLELTKYAI-EKHEPDNNRWIKVA 1717 D P +PE + E R +K P + + + Y E+ DNN +KV Sbjct: 85 KDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNN--VKV- 141 Query: 1718 DVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXX 1777 + R + + ++ +N G +EA+ S+ IV LD P+ Sbjct: 142 EKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAI-SQLIV----LDKPTPPLGPAETT 196 Query: 1778 XIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXX-XXXXARIQKLSINTTY 1835 V W P + +GGSP+ Y +E +Q G+ WK R + Y Sbjct: 197 ESSATCVEFKWRPPKDDGGSPVTHYLMERQQVGRNTWKKLGEIPGVPRHRDTDVEHGRKY 256 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 +RI+A GTS D++ G TL P P V + + + W P + GGS Sbjct: 257 CYRIWAVTAEGTS-EMMETDEMQAG-TLAFPGPPAPPAVVSAFDDCINIAWEAPSNRGGS 314 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEH--CIENIKEKDEIIFRISAENTVGVSLPTE 1953 I Y++E + W+ I + E + ++ E FR++A N GV + Sbjct: 315 RILGYLVEKRKKGSNLWSTINATDDLIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSS 374 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA--PLLGYNIAIRDVTKT 2011 + P L++ + +W PE G GY I +R Sbjct: 375 PSEFVFARDPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCI 434 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 W + T F++R L Y R+ A N+ G P E + +P Sbjct: 435 EWSRCNTSPLITTSFSVRGLKHMDMYWARVTATNDGGDGPPEELQKYITAMP 486 Score = 89.0 bits (211), Expect = 1e-15 Identities = 62/240 (25%), Positives = 112/240 (46%), Gaps = 16/240 (6%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K G+ V +++ ++A P P+ W+ ++ + K + T + DS S+ L I E +D+G+Y Sbjct: 504 VKAGNSVRIMMHFEASPLPDIMWLKDNVPVTK-RVTISNSDS-SSQLLIPSSERSDSGVY 561 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + ++N G + V + D P PPG + E ++ + W + ++Y V Sbjct: 562 SVLVKNLAGQETFSIEVRVTDDPRPPGPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVS 621 Query: 1419 YQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET----TEYYK- 1472 + W +V + + + ++ N Y FR YA N++ IS SE+ TE K Sbjct: 622 KLDSTKGTWATVADRLFNNRFTVCNTMHGRVYHFRVYAKNDMGISPPSESPTWGTEKKKE 681 Query: 1473 -------VIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 ++ +Q P V PLK + ++C G P+P++TWYR+ L T Sbjct: 682 RFALSTPAHRDRDMQCPPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNT 741 Score = 84.6 bits (200), Expect = 3e-14 Identities = 56/263 (21%), Positives = 113/263 (42%), Gaps = 4/263 (1%) Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 N A L ++ E + W+K+ I ++F +I + LII KC E+ +Y V Sbjct: 14 NEAAELMCKLSSEDCEGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVA 73 Query: 1271 LDAKSTTKLKV-EVVEFPPK-IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 K+ + V + F P+ + + +++ G + + + +W + + Sbjct: 74 DGRKTEAMINVKDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEEL 133 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKP 1387 + K + L + + + D G K++L+N G + + +LDKP+PP G Sbjct: 134 LGDNNVKVEKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAISQLIVLDKPTPPLGPA 193 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT-QTSIQNLKTN 1446 E ++ + W P++ G S + +Y++E Q++ W + I + +++ Sbjct: 194 ETTESSATCVEFKWRPPKDDGGSPVTHYLMERQQVGRNTWKKLGEIPGVPRHRDTDVEHG 253 Query: 1447 SSYRFRAYAVNEVDISDASETTE 1469 Y +R +AV S+ ET E Sbjct: 254 RKYCYRIWAVTAEGTSEMMETDE 276 Score = 72.5 bits (170), Expect = 1e-10 Identities = 48/172 (27%), Positives = 79/172 (45%), Gaps = 6/172 (3%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 K G+ + E P P+++W K+ + K I+ + +S + I +RS S Y+ Sbjct: 505 KAGNSVRIMMHFEASPLPDIMWLKDNVPVT--KRVTISNSDSSSQLLIPSSERSDSGVYS 562 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + N AG + + ++V D P +P GP+ + E +VT+ W P D+ + Y + Sbjct: 563 VLVKNLAGQETFSIEVRVTDDP-RPPGPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVS 621 Query: 1705 KHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 K + W VAD + + T C Y FRV A+N +G S ES Sbjct: 622 KLDSTKGTWATVADRLFNNRFTVC--NTMHGRVYHFRVYAKNDMGISPPSES 671 Score = 72.1 bits (169), Expect = 2e-10 Identities = 104/450 (23%), Positives = 168/450 (37%), Gaps = 35/450 (7%) Query: 1625 EKTSVIRIKELKRSHSSKYT--IEASNTAGTSSV----EVTLKVYDKPSKPEGPVIMREI 1678 E V R ++ H KY I A GTS + E+ P P P ++ Sbjct: 238 EIPGVPRHRDTDVEHGRKYCYRIWAVTAEGTSEMMETDEMQAGTLAFPGPPAPPAVVSAF 297 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV-ETYC-IQKLNENCE 1736 + + I W+ P + GG + Y +EK + +N W + D + E C ++ + E Sbjct: 298 D-DCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTINATDDLIKEKKCAVRDVVSGME 356 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNG 1795 Y FRV A N G E V P +TW P EK G Sbjct: 357 YEFRVTAVNLSGVGECSSPSEFVFARDPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPG 416 Query: 1796 -GSPIIDYKVEIKQ-EGKKWKXXXXX--XXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851 Y ++++Q + +W ++ L Y R+ A N+ G P Sbjct: 417 IQDEAKGYFIDVRQADCIEWSRCNTSPLITTSFSVRGLKHMDMYWARVTATNDGGDGPPE 476 Query: 1852 TSDDKITIGKTLTPPS----QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 IT P + ++F+V ++ + + E SP+ + I+ K Sbjct: 477 ELQKYITAMPRPVRPKFTNHKMKSFMVVKAGNSVRIMMHFE-----ASPLPD-IMWLKD- 529 Query: 1908 KGKSWTKIVTVGGS--VHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965 TK VT+ S + I + + D ++ + +N G T S VR+ Sbjct: 530 -NVPVTKRVTISNSDSSSQLLIPSSERSDSGVYSVLVKNLAGQE--TFSIEVRVTDD--- 583 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP P+E+ V +W + L Y ++ D TK W V N + Sbjct: 584 PRPP-GPIEVEENVPGTVTLTWLPSPDEKLDDRLHYTVSKLDSTKGTWATVADRLFNN-R 641 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 F + + Y R+YA+N++G+S P ES Sbjct: 642 FTVCNTMHGRVYHFRVYAKNDMGISPPSES 671 Score = 58.0 bits (134), Expect = 3e-06 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 4/103 (3%) Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 EM L P PP P ++ INI W+ P N G S I+ Y+VE ++ + W ++ Sbjct: 276 EMQAGTLAFPGPPAPPAVVSAFDDCINIAWEAPSNRGGSRILGYLVEKRKKGSNLWSTIN 335 Query: 1432 N----ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I + + +++++ + Y FR AVN + + S +E+ Sbjct: 336 ATDDLIKEKKCAVRDVVSGMEYEFRVTAVNLSGVGECSSPSEF 378 Score = 56.4 bits (130), Expect = 8e-06 Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP I PLK +G +S V GNP+P ITW +N+ + +T + L Sbjct: 698 PPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYISNTCGVCSLL 757 Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITV 822 +V KD G YT+ AE+++G AE S V++V Sbjct: 758 ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788 Score = 56.0 bits (129), Expect = 1e-05 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F+ L+ + P G C V G P+P+ITW+R + ++ + + V +L+ Sbjct: 699 PVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYI-SNTCGVCSLL 757 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 I V P+D G +T A++ G A +T L V Sbjct: 758 ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788 Score = 48.4 bits (110), Expect = 0.002 Identities = 45/185 (24%), Positives = 85/185 (45%), Gaps = 13/185 (7%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V+E ++++ C+L + + + W +G +I PD+ + E +H L IT K+ Sbjct: 13 VNEAAELM--CKLSS-EDCEGVWFKEGRKIPPDDQFCIIREGAVHK----LIITKCKEEH 65 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y VA R+ EA + + + ++ EP+K VR G++ + +G Sbjct: 66 SGKYRFVADGRKTEAMINVKDPPRFRPEDVCVFTEPVK---VRAGQNAMFKMPFIGQEPI 122 Query: 765 TITWCKNNKPVKA-LPTKSDG-DTHSITILKPKKVKDEGVYTLKAENSEGIAET-SAVIT 821 I W + + + K + + S +L + KD G +K +N G+ E S +I Sbjct: 123 RIQWYREGEELLGDNNVKVEKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTEAISQLIV 182 Query: 822 VEEPT 826 +++PT Sbjct: 183 LDKPT 187 Score = 48.4 bits (110), Expect = 0.002 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 M+V+ G SV + +P P I W K+N PV T S+ D+ S ++ + D GVY Sbjct: 502 MVVKAGNSVRIMMHFEASPLPDIMWLKDNVPVTKRVTISNSDSSSQLLIPSSERSDSGVY 561 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPP 833 ++ +N G ET ++E ++ PP Sbjct: 562 SVLVKNLAG-QET---FSIEVRVTDDPRPP 587 Score = 41.1 bits (92), Expect = 0.33 Identities = 34/160 (21%), Positives = 58/160 (36%), Gaps = 8/160 (5%) Query: 1379 DKPSPPGKPNILEIDSSSIN---ICWDEPENTGN--STIIYYVVEYQEIDTTEW--ISVK 1431 D PPGK L++ +S + W +PE Y ++ ++ D EW + Sbjct: 383 DPKKPPGKVVGLKVSETSYTHFVLTWTKPEEKPGIQDEAKGYFIDVRQADCIEWSRCNTS 442 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 + T S++ LK Y R A N+ E +Y + T K + Sbjct: 443 PLITTSFSVRGLKHMDMYWARVTATNDGGDGPPEELQKYITAMPRPVRPKFTNHKMKSFM 502 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 + + + F P P + W +D + T + T N Sbjct: 503 VVKAGNSVRIMMHFEASPLPDIMWLKDNVPV-TKRVTISN 541 Score = 41.1 bits (92), Expect = 0.33 Identities = 21/76 (27%), Positives = 32/76 (42%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G P P + WY+N L D Y I+ + I + +YTI Sbjct: 713 GYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYISNTCGVCSLLILRVGPKDMGEYTIT 772 Query: 1647 ASNTAGTSSVEVTLKV 1662 A +T G + L V Sbjct: 773 AESTQGRAECSTVLSV 788 Score = 38.3 bits (85), Expect = 2.3 Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 4/95 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K +G + + C + P+P I W + D N + S+ C Sbjct: 698 PPVFIVPLKLHNAPKGYECYMSCAVTGNPKPRITWYRNHVSLNTDTNYYI---SNTCGVC 754 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 S+L I V G YT+ A + +G A VL + Sbjct: 755 SLL-ILRVGPKDMGEYTITAESTQGRAECSTVLSV 788 Score = 37.9 bits (84), Expect = 3.0 Identities = 32/154 (20%), Positives = 61/154 (39%), Gaps = 4/154 (2%) Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188 +L+ D WFK+G +I + + +G KL I C + +G+Y K A+ Sbjct: 22 KLSSEDCEGVWFKEGRKIPPDDQFCIIREGAVHKLIITKCKEEHSGKYRFVADGRKTEAM 81 Query: 1189 LTVEEP---SINFTLRLPEFILVPANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKFTL 1244 + V++P E + V A +A + I E + + WY++ + + Sbjct: 82 INVKDPPRFRPEDVCVFTEPVKVRAGQNAMFKMPFIGQEPIRIQWYREGEELLGDNNVKV 141 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK 1278 + L++ +C D E L + T+ Sbjct: 142 EKCRSQSRLLLSRCQRKDTGEIKIKLKNQHGVTE 175 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 833 PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P F N + + VK +++++ +P+P I W ++N ++ TI+ N D + +L Sbjct: 491 PKFTNHKMKSFMVVKAGNSVRIMMHFEASPLPDIMWLKDNVPVTKRVTIS-NSDSSS-QL 548 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +I + + DSG Y + N AG+ + V + Sbjct: 549 LIPSSERS-DSGVYSVLVKNLAGQETFSIEVRV 580 >UniRef50_Q4R5Y9 Cluster: Testis cDNA, clone: QtsA-19723, similar to human palladin (KIAA0992),; n=3; Eutheria|Rep: Testis cDNA, clone: QtsA-19723, similar to human palladin (KIAA0992), - Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) Length = 452 Score = 127 bits (306), Expect = 4e-27 Identities = 97/336 (28%), Positives = 148/336 (44%), Gaps = 20/336 (5%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYD 561 S E MAP F KL+ +G V F C+V G P+P+I WF+ I P D + + D Sbjct: 63 SVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 122 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA-------PLSDHGSEMTVX 614 D +L +D G +T +A N G S T L+V+A P S G Sbjct: 123 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 182 Query: 615 XXXXXXXXXXXADILEG--IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672 + ++ P F + P V EG ++C++ +P PD++W G+ Sbjct: 183 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 242 Query: 673 EIVPDENISVAI-ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 I PD + + E+ +H L I V G YT +A NR G+ S + L + E Sbjct: 243 PIRPDSAHKMLVRENGVHS----LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 298 Query: 732 -KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDT 786 +PP IE L++ V G V L +V+G P P I W K N+ + + D Sbjct: 299 AHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHG 358 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + +++ +D G YT+ A+N GI +A + V Sbjct: 359 YICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 394 Score = 89.4 bits (212), Expect = 9e-16 Identities = 86/333 (25%), Positives = 143/333 (42%), Gaps = 45/333 (13%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G+ P F K K + EG + CR+ P+P I W G++I P + I+ D+ Sbjct: 67 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDG 125 Query: 691 YCSVLKITNVKKFQEGTYT-----------------VVAVNREGEASL-----PIVLKIK 728 CS L T +G YT V AVN+ G + P V + + Sbjct: 126 TCS-LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 184 Query: 729 T------GEKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 + E EP P ++ + V++G+ + +V G P P ++W + KP+ Sbjct: 185 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPI 244 Query: 776 KALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + + HS+ I++P +D G+YT A N G S + V +E + Sbjct: 245 RPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA--AKEAHK 301 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIEL 890 PP+FI + Q V + ++L RV P P I W + NE ++ S + ++ + D Sbjct: 302 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 361 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ ++ D+G Y A N AG S AR+ + Sbjct: 362 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 394 Score = 86.2 bits (204), Expect = 9e-15 Identities = 68/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E +E+ P F++ +G + +C+V G P P ++W I+P +M Sbjct: 193 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKM 252 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618 ++ V +L+I V DAG +TC+A N AG S + EL V A H Sbjct: 253 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK---------- 301 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 PP F +K + V +G + LECR++ +P P I W + E + Sbjct: 302 --------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 347 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 + V++ D H Y +L I K G YTV A N G S L + T + Q Sbjct: 348 D-RVSMHQDNHGYICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQST 405 Query: 739 EPLK 742 +P K Sbjct: 406 KPKK 409 Score = 53.2 bits (122), Expect = 8e-05 Identities = 36/153 (23%), Positives = 69/153 (45%), Gaps = 6/153 (3%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 EP +E P F+ ++TV+E ++ +V+ P P ++W + + I P Sbjct: 195 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLV 254 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939 + +I + D+G Y C+A+N AG++S + + ++ F++ LQ + Sbjct: 255 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-G 313 Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972 +G V LEC+ + + KKE + H Sbjct: 314 VADGYPVRLECRVLGVPPPQIFW-KKENESLTH 345 Score = 50.0 bits (114), Expect = 7e-04 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 16/187 (8%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544 ++T + + + C G+P P ++W DGK ++ A EN Sbjct: 212 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLIIEPVTSRD 271 Query: 1545 XXXYKCIAFNDHGEVETS--CVVGIQQ--KPVITISNEDIKQKHKVGDEWLV--TAVIEG 1598 Y CIA N G+ S VV ++ KP + I Q V D + V + G Sbjct: 272 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLG 328 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSV 1656 +PPP++ W K L + + ++ I I+ + + YT+ A N AG S Sbjct: 329 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 388 Query: 1657 EVTLKVY 1663 L VY Sbjct: 389 TARLDVY 395 Score = 48.0 bits (109), Expect = 0.003 Identities = 49/191 (25%), Positives = 78/191 (40%), Gaps = 16/191 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D V+E + ++ +++ T D+ W+ DG+ I+P + + L Sbjct: 204 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLI 263 Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y+CI + S + E+ V PP I +LQN V G E Sbjct: 264 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 323 Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180 L + W K+ + S + + + D L I +DAG Y+ E Sbjct: 324 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 383 Query: 1181 GNSKCTAILTV 1191 G CTA L V Sbjct: 384 GIVSCTARLDV 394 Score = 46.8 bits (106), Expect = 0.007 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 7/115 (6%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + E+ + + + EN P F + + + E + RV NP P I W+++ + Sbjct: 50 VDESGDEVQYGDVSVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 109 Query: 873 ISPSE---TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ISP TI ++ DG ++ + +D D G+Y +A+N G+ S R+ + Sbjct: 110 ISPKSDHYTIQRDLDGTCSLHTTASTLD---DDGNYTIMAANPQGRISCTGRLMV 161 Score = 40.3 bits (90), Expect = 0.57 Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 Y + + ++ + +Y V E + +P E LK+ + TC G P+PK+ Sbjct: 43 YRLERSPVDESGDEVQYGDVSVENGM-APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKI 101 Query: 1514 TWYRDGKKLKTAKATY 1529 W++DGK++ Y Sbjct: 102 YWFKDGKQISPKSDHY 117 >UniRef50_Q8WX93 Cluster: Palladin; n=14; Euarchontoglires|Rep: Palladin - Homo sapiens (Human) Length = 1383 Score = 127 bits (306), Expect = 4e-27 Identities = 102/367 (27%), Positives = 162/367 (44%), Gaps = 23/367 (6%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 Q L+ E Y + + ++E D++ + P E MAP F KL+ +G V F C Sbjct: 966 QRLISEIEY-RLERSPVDESGDEVQYGDVPV--ENGMAPFFEMKLKHYKIFEGMPVTFTC 1022 Query: 532 QVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +V G P+P+I WF+ I P D + + D D +L +D G +T +A N G Sbjct: 1023 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 1082 Query: 591 FASSTTELIVEA-------PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK 641 S T L+V+A P S G + ++ P F + P Sbjct: 1083 RISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPG 1142 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNV 700 V EG ++C++ +P PD++W G+ + PD + + E+ +H L I V Sbjct: 1143 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS----LIIEPV 1198 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVV 759 G YT +A NR G+ S + L + E +PP IE L++ V G V L +V+ Sbjct: 1199 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1258 Query: 760 GNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G P P I W K N+ + + D + +++ +D G YT+ A+N GI Sbjct: 1259 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1318 Query: 816 TSAVITV 822 +A + V Sbjct: 1319 CTARLDV 1325 Score = 89.8 bits (213), Expect = 7e-16 Identities = 87/333 (26%), Positives = 143/333 (42%), Gaps = 45/333 (13%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G+ P F K K + EG + CR+ P+P I W G++I P + I+ D+ Sbjct: 998 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDG 1056 Query: 691 YCSVLKITNVKKFQEGTYT-----------------VVAVNREGEASL-----PIVLKIK 728 CS L T +G YT V AVN+ G + P V + + Sbjct: 1057 TCS-LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 1115 Query: 729 T------GEKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 + E EP P ++ + V++G+ + +V G P P ++W + KPV Sbjct: 1116 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 1175 Query: 776 KALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + + HS+ I++P +D G+YT A N G S + V +E + Sbjct: 1176 RPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA--AKEAHK 1232 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIEL 890 PP+FI + Q V + ++L RV P P I W + NE ++ S + ++ + D Sbjct: 1233 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1292 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ ++ D+G Y A N AG S AR+ + Sbjct: 1293 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1325 Score = 85.8 bits (203), Expect = 1e-14 Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E +E+ P F++ +G + +C+V G P P ++W ++P +M Sbjct: 1124 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 1183 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXX 618 ++ V +L+I V DAG +TC+A N AG S + EL V A H Sbjct: 1184 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL-VVAAKEAHK---------- 1232 Query: 619 XXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 PP F +K + V +G + LECR++ +P P I W + E + Sbjct: 1233 --------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 1278 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 + V++ D H Y +L I K G YTV A N G S L + T + Q Sbjct: 1279 D-RVSMHQDNHGYICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQST 1336 Query: 739 EPLK 742 +P K Sbjct: 1337 KPKK 1340 Score = 83.0 bits (196), Expect = 8e-14 Identities = 42/107 (39%), Positives = 64/107 (59%), Gaps = 7/107 (6%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-------DD 562 P+F ++L+ +G V EC+V G P Q+ WFRQ + I+ S DF++ + Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 + + TLVI E FPEDAG FTC A+N G A+ST +L+V + +++ S Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547 Score = 81.8 bits (193), Expect = 2e-13 Identities = 37/103 (35%), Positives = 63/103 (61%), Gaps = 1/103 (0%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F++KLR + +GS V EC+V G P P++ WF + + + D Q++ + ++ TL Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE-APLSDHGSE 610 +I E F +D G +TC+A N +G +++ E+ +E A +D SE Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372 Score = 53.2 bits (122), Expect = 8e-05 Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 8/138 (5%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSIT 790 P+ I+ L+S V +G V L +V GNP P + W K + P GD H++ Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPPLFINRFQEITVKEKG 848 I + + D G YT A N G TSA + +E T+ ++E F +R + +K Sbjct: 331 IAEAFE-DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389 Query: 849 TIKLVARV-TRNPVPSIT 865 T + + + +P +T Sbjct: 390 TTSVSLTIGSSSPKTGVT 407 Score = 53.2 bits (122), Expect = 8e-05 Identities = 27/92 (29%), Positives = 46/92 (50%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P FI + + V E + L RVT NP P + W+ + + + I + +G ++ +I Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 E D+G Y C+A+N +G + A V I+ Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362 Score = 52.8 bits (121), Expect = 1e-04 Identities = 35/153 (22%), Positives = 69/153 (45%), Gaps = 6/153 (3%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 EP +E P F+ ++TV+E ++ +V+ P P ++W + + + P Sbjct: 1126 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLV 1185 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939 + +I + D+G Y C+A+N AG++S + + ++ F++ LQ + Sbjct: 1186 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-G 1244 Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972 +G V LEC+ + + KKE + H Sbjct: 1245 VADGYPVRLECRVLGVPPPQIFW-KKENESLTH 1276 Score = 50.4 bits (115), Expect = 5e-04 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE-SDMHMYC 692 P F +K ++Q V EGS + LECR+ P P + W +G+E+ +I + E D+H Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH--- 327 Query: 693 SVLKITNVKKFQEGTYTVVAVNREG 717 L I + G YT +A N G Sbjct: 328 -TLIIAEAFEDDTGRYTCLATNPSG 351 Score = 49.6 bits (113), Expect = 0.001 Identities = 47/187 (25%), Positives = 74/187 (39%), Gaps = 16/187 (8%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544 ++T + + + C G+P P ++W DGK ++ A EN Sbjct: 1143 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 1202 Query: 1545 XXXYKCIAFNDHGEVETS--CVVGIQQ--KPVITISNEDIKQKHKVGDEWLV--TAVIEG 1598 Y CIA N G+ S VV ++ KP + I Q V D + V + G Sbjct: 1203 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLG 1259 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSV 1656 +PPP++ W K L + + ++ I I+ + + YT+ A N AG S Sbjct: 1260 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 1319 Query: 1657 EVTLKVY 1663 L VY Sbjct: 1320 TARLDVY 1326 Score = 47.6 bits (108), Expect = 0.004 Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 16/191 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D V+E + ++ +++ T D+ W+ DG+ ++P + + L Sbjct: 1135 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 1194 Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y+CI + S + E+ V PP I +LQN V G E Sbjct: 1195 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1254 Query: 1128 IE-LTKGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180 L + W K+ + S + + + D L I +DAG Y+ E Sbjct: 1255 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1314 Query: 1181 GNSKCTAILTV 1191 G CTA L V Sbjct: 1315 GIVSCTARLDV 1325 Score = 46.4 bits (105), Expect = 0.009 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---TITQNFD 884 EN P F + + + E + RV NP P I W+++ + ISP TI ++ D Sbjct: 996 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 1055 Query: 885 GE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 G ++ + +D D G+Y +A+N G+ S R+ + Sbjct: 1056 GTCSLHTTASTLD---DDGNYTIMAANPQGRISCTGRLMV 1092 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID-GKKQKLK 1164 P I +L++Q+V +G++ E +T VRWF +G E+ + IQ+ + G L Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 I + DD G Y+C N Sbjct: 331 IAEAFEDDTGRYTCLATN 348 Score = 39.9 bits (89), Expect = 0.75 Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 Y + + ++ + +Y V E + +P E LK+ + TC G P+PK+ Sbjct: 974 YRLERSPVDESGDEVQYGDVPVENGM-APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKI 1032 Query: 1514 TWYRDGKKLKTAKATY 1529 W++DGK++ Y Sbjct: 1033 YWFKDGKQISPKSDHY 1048 Score = 39.5 bits (88), Expect = 0.99 Identities = 62/278 (22%), Positives = 101/278 (36%), Gaps = 30/278 (10%) Query: 930 FVKHLQKSYETEEGKTVILECQTSH--TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 F++ L +S E EG V LEC+ + T +W+ KE+ +I EG Sbjct: 273 FIQKL-RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331 Query: 988 XXXXXD-VGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D G C+ + +T++ V E + K + A+ + + + Sbjct: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTT 391 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVV 1103 + + PK I+ L + VH Y C R + T Sbjct: 392 SVSLTIGSSS----PKTGV----TTAVIQPLSVPVQQVHSPTSYLC--RPDG----TTTA 437 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQK 1162 PP LQN V +G E + L V+WF+ GSEIQ S ++ + Sbjct: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497 Query: 1163 LKIYD-CDL-------DDAGEYSCEVGNSKCTAILTVE 1192 + + C L +DAG ++C N +A T + Sbjct: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535 Score = 38.3 bits (85), Expect = 2.3 Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 10/106 (9%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--------TKSDGD 785 PP + L++ V +G+ V+L +V G P + W + ++ P +S + Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499 Query: 786 THSITILKPKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 I L + +D G++T A N G A ++A + V EN Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545 Score = 37.9 bits (84), Expect = 3.0 Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 4/105 (3%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENISVAIESDMHM 690 PP F+K+ + V EG ++LECR+ P + W +G EI PD I Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499 Query: 691 YCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKE 733 + + + F E G +T A N G A+ L + + E Sbjct: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE 544 Score = 36.3 bits (80), Expect = 9.2 Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 9/100 (9%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIE 889 PP+F Q V E + L RV P + W+R I SP I Q E Sbjct: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499 Query: 890 ------LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 LVI E D+G + C A N G ++ A++ + Sbjct: 500 PEEICTLVIAETFPE-DAGIFTCSARNDYGSATSTAQLVV 538 >UniRef50_UPI0000D8E943 Cluster: Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).; n=1; Danio rerio|Rep: Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2). - Danio rerio Length = 1862 Score = 126 bits (303), Expect = 9e-27 Identities = 280/1349 (20%), Positives = 487/1349 (36%), Gaps = 128/1349 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G I L C P P I WL G + D + + L I++++ Sbjct: 70 VQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG--------LTISDLRLED 121 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y N G + L + EP +V K++ +VILS V G+P Sbjct: 122 SGNYICEVTNSFGSKEVTGHLNVI----EPLRVTLSPKNLKTGISSTVILSCAVQGSPHF 177 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 T++W +N +P+ S H+ T+ + + + G Y A A+ ++I +E Sbjct: 178 TVSWFRNTEPIVPDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLE 237 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN- 882 + T P ++ F E V L+ P P+ITW ++E ++ + Sbjct: 238 DGT------PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQ 291 Query: 883 ---FDGENIELV-ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 DG + V +TN D G Y+C A NSAG + + AR I+V ++ + ++ Sbjct: 292 YTLSDGSTVSHVNVTNPQIR-DGGVYRCAARNSAGSAEYQAR--INVRGPPSIRAM-RNI 347 Query: 939 ETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 G+ + C+ S KWY + + +HR+++ E D G Sbjct: 348 TAVAGRNTFINCRVIGYPYYSIKWYKDGMLLPD-NHRQVVYE-NGTLKLSDVQKGMDEGA 405 Query: 997 IKCIVKDQ---ETSTMLVVKETIPEFIRKLQDF---EVKEKDVAILEVEINSETADVVWE 1050 C V Q S + V +P I+ DF + + V + W Sbjct: 406 YLCSVLIQPQLSISQTVYVTVKVPPLIQPF-DFPPTSIGKLMYIACVVSSGDMPIRITWR 464 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTVVELPP 1107 +DG+ I E + + L I S+ G Y+CI +++ T +V +PP Sbjct: 465 KDGQEIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPP 524 Query: 1108 EIITRLQNQK--VNKGNKATFEIELTKGDALVRWFKDG-------SEIQFSNHIQLTIDG 1158 + NQ K +E +V G + + IQ+ +G Sbjct: 525 RFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNG 584 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANTD 1213 L I +D G Y C+ N + +LTV+ P++ + + N + Sbjct: 585 ---SLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSHPNTTMAIKGQNKE 641 Query: 1214 AYLTVEIPDETLDVTWYKKKSVIED--TEKFTLI------SDVKKRTLIIRKCTEDDQCE 1265 T + + + W + +VI+ ++++ SD TL ++ D Sbjct: 642 LNCTAR-GEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERGDSVF 700 Query: 1266 YTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDV--TLLVDYQAFPQPNDEWI 1322 ++C +++ + +++ V+ PP + E R ++ T D + D Sbjct: 701 FSCHAINSYGEGRGLIQLTVQEPPDPPELEVREVKDRSMNLRWTQRFDGNSIITSYDIEY 760 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVEMNVTILDK 1380 N + KH I + I VE A +Y +R+ N G + +TI + Sbjct: 761 KNKSDPWELKHATRKISPTNNQANI--VELHPASVYSIRMYSYNKIGRSQASKELTISTE 818 Query: 1381 PSPPGKPN---ILE-IDSSSINICWDEP-ENTGNSTIIYYVVEYQE--IDTTEWISVKNI 1433 +PP P IL+ + S SI + W P + N I Y + Y+E + S+ + Sbjct: 819 EAPPDGPPMEVILQPMTSQSIRVTWKAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEM 878 Query: 1434 TKTQTS----IQNLKTNSSYRFRAYAVNEVDISDASE-----TTEYYKVIKETKIQSPTV 1484 T S + NLK + Y A N +S T E +++ TV Sbjct: 879 KATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPQNVRAITV 938 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544 IT + L + G + Y DG+ + T R Sbjct: 939 TSDEAVITWSEPPRMTLNGVLKGYRVVFWSLYPDGEWGEMQNIT-TTREQVELKGLEKFT 997 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK----QKHKVGDEWLVTAVIEGIP 1600 + +A+ G+ S V+ IQ + IK V WL GI Sbjct: 998 NYSVQVLAYTQAGDGVRSNVLYIQTREDHPGPPAGIKAVPSSASSVVVSWLPPVKPNGII 1057 Query: 1601 PPEVIWYKN-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 I+ + G+ EY + + RI L R A TAG ++ Sbjct: 1058 RKYTIYCSSPGSGQPAPSEYE--ANPELLIYRITHLTRGQQYLIWAAAVTTAGRGNISEK 1115 Query: 1660 LKVYDKPSKPEGPVIMREIS-RESVTIEW----KPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + V +P G + +S +VT W + P G E T + ++ Sbjct: 1116 VTV-----EPAGKAPAKILSFGGTVTTPWMKEVRLPCSSVG-EPTPTIKWTKDSEDTAIP 1169 Query: 1715 KVADVDRDV---ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 D R++ T ++ + + A N +GF + I++ + VP Sbjct: 1170 VTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGF------DTIIVNLLVQVPPDQP 1223 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXA-RIQKL 1829 S+ + W P + NGGS I + ++ + ++WK + ++ L Sbjct: 1224 RLTVSTT-STSSITLAWIPGD-NGGSSIRGFVLQYSVDNTEEWKDVFISSSERSFKLDNL 1281 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK-WTE 1888 T Y+ ++ A+N +G + T G+ F ST + L+ WT Sbjct: 1282 RCGTWYKVKLAAKNSVGAGRISEIIEAKTHGREPQFNKDQPLFTHINSTHARMNLQGWT- 1340 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 +GG PIT ++EF+ +W + T Sbjct: 1341 ---SGGCPITAVLLEFRPKGTWAWQSVRT 1366 Score = 120 bits (289), Expect = 4e-25 Identities = 199/995 (20%), Positives = 370/995 (37%), Gaps = 90/995 (9%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 E P ++ Q+ +V G I + +RW KDG + + + G Sbjct: 56 ESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRLTG---- 111 Query: 1163 LKIYDCDLDDAGEYSCEVGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 L I D L+D+G Y CEV NS + T L V EP + TL P+ + ++ L+ Sbjct: 112 LTISDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEP-LRVTLS-PKNLKTGISSTVILSC 169 Query: 1219 EIPDET-LDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTT 1277 + V+W++ I + F+ I TL I + Y C K T Sbjct: 170 AVQGSPHFTVSWFRNTEPIVPDQHFS-IQGAHNETLFITAAQKRHSGAYQC-FATRKGQT 227 Query: 1278 KLKVEVV---EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 ++ + P+IV E + G +L+ + P P W ++ + + + Sbjct: 228 AQDFSIILLEDGTPRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAH 287 Query: 1335 KPSIDSKSASLTIKKVENT-----DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + S + S T+ V T D G+Y+ N+ G A+ + + + PS NI Sbjct: 288 RASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRNI 347 Query: 1390 LEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 + + I C +I +Y D + +N T + +Q + Sbjct: 348 TAVAGRNTFINC--RVIGYPYYSIKWYKDGMLLPDNHRQVVYENGTLKLSDVQKGMDEGA 405 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGV 1508 Y ++ IS T ++ P + +P T + + + C+ Sbjct: 406 YLCSVLIQPQLSISQTVYVT----------VKVPPLIQPFDFPPTSIGKLMYIACVVSSG 455 Query: 1509 PQP-KVTWYRDGKKL--KTAKATYENR---XXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 P ++TW +DG+++ TA T E + Y CIA ND V + Sbjct: 456 DMPIRITWRKDGQEIVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSE 515 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-- 1620 + + P + + Q G ++ +EG PPP+V+W K+ + N ++Y+ Sbjct: 516 RQLIVTVPPRFRVQPNN--QDGIYGKSEVLNCSVEGYPPPKVVW-KHAKGIGNPQQYHPV 572 Query: 1621 -ITTKEK---TSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDK-PSKPEGP 1672 +T + + + I+ + Y +ASN G + S+ +T+K+ S P Sbjct: 573 PLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSHPNTT 632 Query: 1673 VIMREISRE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-----DVDRDVETY 1726 + ++ ++E + T + P+ + + +PD N + D + T Sbjct: 633 MAIKGQNKELNCTARGEYPI----IIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTL 688 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 ++ F A N G L + ++ D P + + S+ + Sbjct: 689 KLKPAERGDSVFFSCHAINSYGEGRGLIQ--LTVQEPPDPPE-----LEVREVKDRSMNL 741 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX-----XXXXARIQKLSINTTYQFRIYA 1841 W +G S I Y +E K + W+ A I +L + Y R+Y+ Sbjct: 742 RW-TQRFDGNSIITSYDIEYKNKSDPWELKHATRKISPTNNQANIVELHPASVYSIRMYS 800 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GGSPITN 1899 N+IG S + ++TI PP P ++ TS+S+ + W P+ I Sbjct: 801 YNKIGRS---QASKELTISTEEAPPDGPPMEVILQPMTSQSIRVTWKAPKKELQNGVIRG 857 Query: 1900 YIIEFKT----VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 Y I ++ G+ + G + ++N+K+ + + A N G P+ S+ Sbjct: 858 YQIGYRENGPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSE 916 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLLGYNIAIRDV-TKTMW 2013 + VPS P + V S+ + +W P L GY + + W Sbjct: 917 -INATTLEDVPSQPPQNVRAITVTSDEAVITWSEPPRMTLNGVLKGYRVVFWSLYPDGEW 975 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 E+ + + ++ L + Y +++ A + G Sbjct: 976 GEMQNITTTREQVELKGLEKFTNYSVQVLAYTQAG 1010 Score = 117 bits (282), Expect = 3e-24 Identities = 175/814 (21%), Positives = 323/814 (39%), Gaps = 69/814 (8%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784 L + + P V++ +S V+ G S+ L G P PTI W K+ +P+ A ++ Sbjct: 49 LSVLDPTESTPSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPA-DSRWTR 107 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 +TI +++D G Y + NS G E + + V EP P + + Sbjct: 108 RLTGLTI-SDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEPLRVTLSP-------KNLKT 159 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 T+ L V +P +++W+RN E I P + + G + E + + SG Y Sbjct: 160 GISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHF--SIQGAHNETLFITAAQKRHSGAY 217 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWYHN 963 +C A+ + + + ++ V ++ E +++ + + + W + Sbjct: 218 QCFATRKGQTAQDFSIILLEDGTPRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLD 277 Query: 964 KKEIS-GMDHRE---IIQEGRXXXXXXXXX-XXXDVGVIKCIVKDQETSTMLVVKETI-- 1016 + ++ HR + +G D GV +C ++ S + + Sbjct: 278 DEPVARDSAHRASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRG 337 Query: 1017 PEFIRKLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P IR +++ V ++ I I + W +DG ++ P ++ + G ++ Sbjct: 338 PPSIRAMRNITAVAGRNTFINCRVIGYPYYSIKWYKDGMLL-PDNHRQVVYENGTLKLSD 396 Query: 1076 IRNTSVHDEGEYSC-ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT 1131 ++ DEG Y C +L + TV V++PP +I + G ++ Sbjct: 397 VQKGM--DEGAYLCSVLIQPQLSISQTVYVTVKVPP-LIQPFDFPPTSIGKLMYIACVVS 453 Query: 1132 KGDALVR--WFKDGSEIQFSNHIQLTIDGKK--QKLKIYDCDLDDAGEYSCEVGNSKCTA 1187 GD +R W KDG EI S +TI+ K+ L+I L G Y+C N T Sbjct: 454 SGDMPIRITWRKDGQEI-VSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAAT- 511 Query: 1188 ILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLD------VTWYKKKSVIEDTE 1240 E + T+ P F + P N D Y E+ + +++ V W K + + Sbjct: 512 --VSSERQLIVTVP-PRFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQ 568 Query: 1241 KFTL-----ISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDY 1293 + I + +L+IR E+D+ Y C + +K + V+ P I + Sbjct: 569 YHPVPLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSH 628 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI--------DSKSASL 1345 +G + L + W +I ++ + SI D ++L Sbjct: 629 PNTTMAIKGQNKELNCTARGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTL 688 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 +K E D+ + N+ G + +T+ + P PP + + E+ S+N+ W + Sbjct: 689 KLKPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPP-ELEVREVKDRSMNLRWTQ-R 746 Query: 1406 NTGNSTIIYYVVEYQEIDTTEW---ISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 GNS I Y +EY+ + W + + I T Q +I L S Y R Y+ N++ Sbjct: 747 FDGNSIITSYDIEYKN-KSDPWELKHATRKISPTNNQANIVELHPASVYSIRMYSYNKIG 805 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 S AS+ E +E P +E L+ +T++ Sbjct: 806 RSQASK--ELTISTEEAPPDGPPMEVILQPMTSQ 837 Score = 89.4 bits (212), Expect = 9e-16 Identities = 77/287 (26%), Positives = 120/287 (41%), Gaps = 28/287 (9%) Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 +++E + T S PK S ++L C + P ++W E IVPD++ S+ Sbjct: 143 NVIEPLRVTLS--PKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHFSI---- 196 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + L IT +K G Y A + A ++ ++ G P+++ +V Sbjct: 197 -QGAHNETLFITAAQKRHSGAYQCFATRKGQTAQDFSIILLEDGT---PRIVSSFSERVV 252 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVK-------ALPTKSDGDTHSITILKPKKVKD 799 GE L G P PTITW +++PV + T SDG T S + +++D Sbjct: 253 APGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSHVNVTNPQIRD 312 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 GVY A NS G AE A I V P I + IT + RV Sbjct: 313 GGVYRCAARNSAGSAEYQARINVRGPPS--------IRAMRNITAVAGRNTFINCRVIGY 364 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 P SI WY++ ++ + + EN L +++V +D G Y C Sbjct: 365 PYYSIKWYKDGMLLPDNH---RQVVYENGTLKLSDVQKGMDEGAYLC 408 Score = 61.7 bits (143), Expect = 2e-07 Identities = 97/439 (22%), Positives = 168/439 (38%), Gaps = 34/439 (7%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678 NITT + + +K L++ + + A AG L + + P P ++ + Sbjct: 980 NITTTREQ--VELKGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDHPGPPAGIKAVP 1037 Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736 S SV + W PP+ G+ + KY I P + + + + ++ Y I L + Sbjct: 1038 SSASSVVVSWLPPVKPNGI-IRKYTIYCSSPGSGQPAPSEYEANPELLIYRITHLTRGQQ 1096 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y+ A G SE + ++ A P+ +V W + Sbjct: 1097 YLIWAAAVTTAGRGNI--SEKVTVEPAGKAPAKILSFGG-------TVTTPWMKEVRLPC 1147 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852 S + + IK K + LS N T R + G T+ Sbjct: 1148 SSVGEPTPTIKWT-KDSEDTAIPVTQDGHRNILS-NGTLVLRSVKAEDSGYYTCTATNTL 1205 Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 D I + + PP QPR V + STS S+TL W P NGGS I +++++ + Sbjct: 1206 GFDTIIVNLLVQVPPDQPRLTVSTTSTS-SITLAWI-PGDNGGSSIRGFVLQYSVDNTEE 1263 Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS-PPT 1970 W K V + S ++N++ +++A+N+VG S+ + + H P Sbjct: 1264 W-KDVFISSSERSFKLDNLRCGTWYKVKLAAKNSVGAG--RISEIIEAKTHGREPQFNKD 1320 Query: 1971 APLEIRMVGSNIVMTSWGTPEW-DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIR 2029 PL + ++ M G W GG P+ + R W V + + + F + Sbjct: 1321 QPLFTHINSTHARMNLQG---WTSGGCPITAVLLEFRPKGTWAWQSV-RTNASADIF-LA 1375 Query: 2030 DLSENHTYMIRIYARNEIG 2048 +L E Y +++ A N G Sbjct: 1376 ELREATWYELKMKACNSAG 1394 Score = 58.8 bits (136), Expect = 2e-06 Identities = 61/254 (24%), Positives = 101/254 (39%), Gaps = 15/254 (5%) Query: 1598 GIPPPEVIWYKNGNK----LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 G P P + W K+ + D NI + T V+R +K S YT A+NT G Sbjct: 1151 GEPTPTIKWTKDSEDTAIPVTQDGHRNILSNG-TLVLR--SVKAEDSGYYTCTATNTLGF 1207 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 ++ V L V P +P + + S S+T+ W P D+GG + + ++ + DN Sbjct: 1208 DTIIVNLLVQVPPDQPR--LTVSTTSTSSITLAWIPG-DNGGSSIRGFVLQ-YSVDNTEE 1263 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 K + ++ + L Y ++ A+N VG SE I KT P Sbjct: 1264 WKDVFISSSERSFKLDNLRCGTWYKVKLAAKNSVGAGRI--SEIIEAKTHGREPQFNKDQ 1321 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSIN 1832 I++ + +GG PI +E + +G W+ + +L Sbjct: 1322 PLFTHINSTHARMN-LQGWTSGGCPITAVLLEFRPKGTWAWQSVRTNASADIFLAELREA 1380 Query: 1833 TTYQFRIYARNEIG 1846 T Y+ ++ A N G Sbjct: 1381 TWYELKMKACNSAG 1394 Score = 48.8 bits (111), Expect = 0.002 Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 5/110 (4%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPS 553 + EK T E AP + TP V+ C G P P I W + + I + Sbjct: 1112 ISEKVTVEPAGKAPAKILSFGGTVTTPWMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVT 1171 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 QD + TLV+R V ED+G +TC A N GF + L+V+ P Sbjct: 1172 QDGHRNILSNG--TLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQVP 1219 Score = 48.4 bits (110), Expect = 0.002 Identities = 66/382 (17%), Positives = 133/382 (34%), Gaps = 27/382 (7%) Query: 1245 ISDVKKR-TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 ISDV+K L +C + Y+ + ++ E P ++D + ++ G Sbjct: 17 ISDVQKEDALSTYRCITKHK--YSGETRQSNGARLSVLDPTESTPSVMDSFQSGEVQVGR 74 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 + L +P P W+ + + + + LTI + D+G Y + Sbjct: 75 SIELPCIASGYPNPTIRWLKDGRPLPADSRWTRRL----TGLTISDLRLEDSGNYICEVT 130 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 N+ G +V ++ +++ P L+ SS I + + + T+ ++ + I Sbjct: 131 NSFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSPHFTVSWFR-NTEPIV 189 Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 + S++ I + S ++ +A + +T + + +I + +P Sbjct: 190 PDQHFSIQGAHNETLFITAAQKRHSGAYQCFATRK------GQTAQDFSIIL-LEDGTPR 242 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543 + P E L C G P P +TW D + + A ++ Sbjct: 243 IVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTVSH 302 Query: 1544 XXXX---------YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y+C A N G E + ++ P I G + Sbjct: 303 VNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRNITA---VAGRNTFINC 359 Query: 1595 VIEGIPPPEVIWYKNGNKLEND 1616 + G P + WYK+G L ++ Sbjct: 360 RVIGYPYYSIKWYKDGMLLPDN 381 Score = 42.7 bits (96), Expect = 0.11 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD----NVATLVIREVFPEDAG 579 G + C VEGYP P++ W I P Q + + +L+IR V ED G Sbjct: 538 GKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNGSLLIRHVLEEDRG 597 Query: 580 TFTCVAKNAAGF-ASSTTELIVEAP 603 + C A N G S + L V+ P Sbjct: 598 YYLCQASNGVGSDISKSMMLTVKIP 622 Score = 41.9 bits (94), Expect = 0.19 Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Query: 516 LRPKHTPDG--STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 L PK+ G STV C V+G P ++WFR T I P Q F + + TL I Sbjct: 152 LSPKNLKTGISSTVILSCAVQGSPHFTVSWFRNTEPIVPDQHFSI--QGAHNETLFITAA 209 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601 +G + C A A + +++E Sbjct: 210 QKRHSGAYQCFATRKGQTAQDFSIILLE 237 Score = 40.7 bits (91), Expect = 0.43 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%) Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME--VGKVD 2020 TV PP P LE+R V + W T +DG + + Y+I ++ + ++ K+ Sbjct: 719 TVQEPPDPPELEVREVKDRSMNLRW-TQRFDGNSIITSYDIEYKNKSDPWELKHATRKIS 777 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 + NI +L Y IR+Y+ N+IG S+ Sbjct: 778 PTNNQANIVELHPASVYSIRMYSYNKIGRSQ 808 Score = 39.9 bits (89), Expect = 0.75 Identities = 51/260 (19%), Positives = 90/260 (34%), Gaps = 20/260 (7%) Query: 584 VAKNAAGFASSTTELIVEAPLSD----HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 + AG T E + +S H T ++ +PP F + Sbjct: 470 IVSGTAGVTIETKEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPPRFRVQ 529 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKIT 698 P Q G +L C + P P + W P + V + + + + L I Sbjct: 530 PNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNGSLLIR 589 Query: 699 NVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 +V + G Y A N G + S ++L +K P + + + +G++ L+ Sbjct: 590 HVLEEDRGYYLCQASNGVGSDISKSMMLTVKI----PAMITSHPNTTMAIKGQNKELNCT 645 Query: 758 VVGNPRPTITWCKNNK----------PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 G I W + + + P + + S LKP + D ++ A Sbjct: 646 ARGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERGDSVFFSCHA 705 Query: 808 ENSEGIAETSAVITVEEPTE 827 NS G +TV+EP + Sbjct: 706 INSYGEGRGLIQLTVQEPPD 725 Score = 36.7 bits (81), Expect = 7.0 Identities = 22/95 (23%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P ++ + G +++ C GYP P I W + + + + L Sbjct: 59 PSVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLKDGRPLPADSRWTR-----RLTGLT 113 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 I ++ ED+G + C N+ G T L V PL Sbjct: 114 ISDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEPL 148 Score = 36.7 bits (81), Expect = 7.0 Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 4/100 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY---DDDNV 565 P V + G C +G P P ITW + + S Y D V Sbjct: 241 PRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARDSAHRASQYTLSDGSTV 300 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 + + + D G + C A+N+AG A + V P S Sbjct: 301 SHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPS 340 >UniRef50_A7RGL7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 553 Score = 126 bits (303), Expect = 9e-27 Identities = 92/352 (26%), Positives = 151/352 (42%), Gaps = 23/352 (6%) Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 V + EP + W EIVPD + + + L + ++K G Y +A N G Sbjct: 207 VQVEEPSVTWYRNKNEIVPDGRSRTTFDGETYK----LILQDIKIKDAGQYECIASNPIG 262 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 +A + + ++E P + L+ + V +G++V +V G PRPT+ W ++N+P++A Sbjct: 263 KAFCTAEMTVN--KREAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRA 320 Query: 778 -LPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 K D D ++ L KD+GVY NS G A +SA + V ++ A P Sbjct: 321 DTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQV----DKKANKPKV 376 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 I + ++ E + R + P P +TWYRN+ + + DG+ L IT+ Sbjct: 377 IEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDT 436 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955 +D+G YKCVA+N GK + +R +DV + F E +E V + Sbjct: 437 -KLVDTGTYKCVATNEGGKIT--SRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFK 493 Query: 956 VSTK--------WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 V + WY + + + + EI G D G C Sbjct: 494 VRVRGKPVPTIVWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTC 545 Score = 122 bits (294), Expect = 1e-25 Identities = 128/573 (22%), Positives = 231/573 (40%), Gaps = 62/573 (10%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 ++ + P F+++ + I + E +L VT P P + W+R+ +I PS ++DG Sbjct: 10 QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 69 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 L + + + D G YKCV +N+ G S A VT+ + + + +E E+ Sbjct: 70 VSALTVKEAELD-DDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFE-EKQFLE 127 Query: 947 ILECQTSHTV------------STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDV 994 LE Q V + W+ N KE+ H EI G D Sbjct: 128 PLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDA 187 Query: 995 GVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERD-G 1053 G KC+ ++ D E+ + EV++ E V W R+ Sbjct: 188 GSYKCLARN---------------------DVGSAER---LFEVQV--EEPSVTWYRNKN 221 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVEL-PPE 1108 EI+ +++ F+ G KL +++ + D G+Y CI + CTAE+TV + P Sbjct: 222 EIVPDGRSRTTFD--GETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPV 279 Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 +++L+ V +G+ ++ ++ V W++D ++ ++ DG+ L + + Sbjct: 280 FVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSE 339 Query: 1168 CDLDDAGEYSCEVGNSKCTAILTVE---EPSINFTLRLPEF--ILVPANTDAYLTVEIPD 1222 D D G Y+C + NS +A + E + N + + + T+A V Sbjct: 340 ADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSG 399 Query: 1223 -ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTK- 1278 +VTWY+ + + +F L D + +L I D Y CV + K T++ Sbjct: 400 LPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRG 459 Query: 1279 -LKVEVVEFPPKIV--DYEREYRIKRGSD-VTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 L V +F P+ D +E + + SD + V + P P W + ++++ + Sbjct: 460 DLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRF 519 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + + DAG Y N G Sbjct: 520 EIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552 Score = 121 bits (291), Expect = 3e-25 Identities = 89/343 (25%), Positives = 154/343 (44%), Gaps = 26/343 (7%) Query: 764 PTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P++TW +N P T DG+T+ + IL+ K+KD G Y A N G A +A + Sbjct: 212 PSVTWYRNKNEIVPDGRSRTTFDGETYKL-ILQDIKIKDAGQYECIASNPIGKAFCTAEM 270 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 TV + E P+F+++ + + V E + + +V P P++ WYR+N+ + Sbjct: 271 TVNK-----REAPVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWK 325 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK--SY 938 +FDG L ++ D + D G Y CV +NSAG + A + +D +K K ++K Sbjct: 326 MDFDGRVCSLFLSEADCK-DKGVYNCVITNSAGSAFSSAELQVD-KKANKPKVIEKMNDV 383 Query: 939 ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 +T EG + + S WY N ++ + ++G D G Sbjct: 384 QTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGT 443 Query: 997 IKCIVKDQ----ETSTMLVVKET--IPEFI---RKLQDFEVKEKDVAILEVEINSE-TAD 1046 KC+ ++ + L V+E PEF + V+E D +V + + Sbjct: 444 YKCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPT 503 Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 +VW +DGE+++ + +++ RG I + S D G Y+C Sbjct: 504 IVWYKDGEMVRDVR-RFEIRSRGDIYTFATYSASAEDAGTYTC 545 Score = 116 bits (278), Expect = 9e-24 Identities = 101/390 (25%), Positives = 161/390 (41%), Gaps = 45/390 (11%) Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 FE QVE P +TW+R I P + +D + L+++++ +DAG + C+A N Sbjct: 205 FEVQVE---EPSVTWYRNKNEIVPDGRSRTTFDGETYK-LILQDIKIKDAGQYECIASNP 260 Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEG 648 G A T +EMTV P F K + +V EG Sbjct: 261 IGKAFCT-------------AEMTVNKREA---------------PVFVSKLRPLFVTEG 292 Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTY 708 ++ C++ +P P + W + + D + + + CS L ++ +G Y Sbjct: 293 DNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRV---CS-LFLSEADCKDKGVY 348 Query: 709 TVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 V N G A L++ + P+VIE + + +G + G PRP +TW Sbjct: 349 NCVITNSAGSAFSSAELQVDK-KANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTW 407 Query: 769 CKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 +N+ V+ DGD +S+TI K V D G Y A N G + + V E Sbjct: 408 YRNSIKVRNESRFHLSEDGDRYSLTITDTKLV-DTGTYKCVATNEGGKITSRGDLDVRE- 465 Query: 826 TEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 + A + +E + V+E I RV PVP+I WY++ E++ Sbjct: 466 -RQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSR 524 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGK 914 G+ + +E D+G Y C ASN GK Sbjct: 525 GDIYTFATYSASAE-DAGTYTCEASNKLGK 553 Score = 93.9 bits (223), Expect = 4e-17 Identities = 120/563 (21%), Positives = 222/563 (39%), Gaps = 58/563 (10%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSI 789 + P + L+ + + +G+ LS V G P+P + W ++ KP + DG+ ++ Sbjct: 14 DTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSAL 73 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKG 848 T+ + + D + N ++ + V +++ E P+F +EK Sbjct: 74 TVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIF---------EEKQ 124 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 ++ + R PV ++++ P T+T +G+ + D K V Sbjct: 125 FLEPLEIQVRQPV-EVSYHVRGR---PKPTVTWWKNGKELR-------------DGKHVE 167 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEIS 968 S G + + E K L ++ + + E Q S WY NK EI Sbjct: 168 IRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAER--LFEVQVEEP-SVTWYRNKNEIV 224 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE-----TSTMLVVKETIPEFIRKL 1023 +G D G +CI + T+ M V K P F+ KL Sbjct: 225 PDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKL 284 Query: 1024 QDFEVKEKD-VAILEVEINSETADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSV 1081 + V E D V+ + V W RD + ++ K DF+ G + L++ Sbjct: 285 RPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFD--GRVCSLFLSEADC 342 Query: 1082 HDEGEYSCILRDES----CTAEVTVVELP--PEIITRLQNQKVNKGNKATFEIELTK-GD 1134 D+G Y+C++ + + +AE+ V + P++I ++ + + +G +A F++ + Sbjct: 343 KDKGVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPR 402 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAI--LT 1190 V W+++ +++ + L+ DG + L I D L D G Y C N K T+ L Sbjct: 403 PEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLD 462 Query: 1191 VEE----PSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLI 1245 V E P L E ++V + V + + + + WYK ++ D +F + Sbjct: 463 VRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIR 522 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTC 1268 S T + +D YTC Sbjct: 523 SRGDIYTFATYSASAEDAGTYTC 545 Score = 93.1 bits (221), Expect = 8e-17 Identities = 109/485 (22%), Positives = 195/485 (40%), Gaps = 60/485 (12%) Query: 929 TFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXX 986 TF+ L+ E EG L C + +W+ ++ I + +G Sbjct: 17 TFMSKLEP-IEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTV 75 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETI-PEFIRKLQDFE--VKEKD-VAILEVEINS 1042 D GV KC+V + S T+ + +R +D+ +EK + LE+++ Sbjct: 76 KEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQ 135 Query: 1043 ETA-----------DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 V W ++G+ ++ K+ + G LYI + D G Y C+ Sbjct: 136 PVEVSYHVRGRPKPTVTWWKNGKELRDGKH-VEIRSGGTYHTLYILRSEEEDAGSYKCLA 194 Query: 1092 RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH 1151 R++ +AE RL FE+++ + V W+++ +EI Sbjct: 195 RNDVGSAE------------RL------------FEVQVEEPS--VTWYRNKNEIVPDGR 228 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV---EEPSINFTLRLPE 1204 + T DG+ KL + D + DAG+Y C +G + CTA +TV E P LR P Sbjct: 229 SRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEMTVNKREAPVFVSKLR-PL 287 Query: 1205 FILVPANTDAYLTVE-IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 F+ N V +P T++ WY+ + ++ + D + +L + + D+ Sbjct: 288 FVTEGDNVSWMCKVAGMPRPTVE--WYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDK 345 Query: 1264 CEYTCVLLD----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPND 1319 Y CV+ + A S+ +L+V+ PK+++ + + G++ V + P+P Sbjct: 346 GVYNCVITNSAGSAFSSAELQVDKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEV 405 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 W NS ++ S D SLTI + D G YK N G ++ + + Sbjct: 406 TWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLDVRE 465 Query: 1380 KPSPP 1384 + P Sbjct: 466 RQFAP 470 Score = 85.0 bits (201), Expect = 2e-14 Identities = 58/208 (27%), Positives = 101/208 (48%), Gaps = 17/208 (8%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDM 688 +G PTF K + + EG D L C + P+P++ W F+ E ++ P + + ++ Sbjct: 12 KGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQW-FRDEVLIKPSRRFKASYDGNV 70 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGEKEPPQVIEP---L 741 S L + + +G Y V N G +A + ++ K E++ + E L Sbjct: 71 ----SALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFL 126 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVK 798 + + ++ + V +S V G P+PT+TW KN K + K + +S G H++ IL+ ++ + Sbjct: 127 EPLEIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEE-E 185 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPT 826 D G Y A N G AE + VEEP+ Sbjct: 186 DAGSYKCLARNDVGSAERLFEVQVEEPS 213 Score = 82.2 bits (194), Expect = 1e-13 Identities = 95/405 (23%), Positives = 171/405 (42%), Gaps = 64/405 (15%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHI 1071 K P F+ KL+ E+ E D L + +V W RD +IKP + ++ G++ Sbjct: 12 KGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSR-RFKASYDGNV 70 Query: 1072 RKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVE--LPPE-----IITRLQ-----N 1115 L ++ + D+G Y C++ + S A+VTV++ L PE I Q Sbjct: 71 SALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLE 130 Query: 1116 QKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 +V + + ++ + + V W+K+G E++ H+++ G L I + +DAG Sbjct: 131 IQVRQPVEVSYHVR-GRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGS 189 Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 Y C +VG+++ + VEEPS+ + E +PD T+ Sbjct: 190 YKCLARNDVGSAERLFEVQVEEPSVTWYRNKNEI--------------VPDGRSRTTF-- 233 Query: 1232 KKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVEVVEF 1286 D E + LI D+K + D +Y C+ + A T ++ V E Sbjct: 234 ------DGETYKLILQDIKIK----------DAGQYECIASNPIGKAFCTAEMTVNKRE- 276 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P V R + G +V+ + P+P EW +++ ++ K D + SL Sbjct: 277 APVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLF 336 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 + + + D G+Y + N+ G A + + DK + KP ++E Sbjct: 337 LSEADCKDKGVYNCVITNSAGSAFSSAELQV-DKKA--NKPKVIE 378 Score = 77.4 bits (182), Expect = 4e-12 Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +++ P F+ KL P +G Q C V G P+P++ WFR +IKPS+ F+ Y D Sbjct: 10 QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASY-DG 68 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 NV+ L ++E +D G + CV N G SS ++ V Sbjct: 69 NVSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTV 105 Score = 74.1 bits (174), Expect = 4e-11 Identities = 35/93 (37%), Positives = 53/93 (56%), Gaps = 1/93 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+FV KLRP +G V + C+V G PRP + W+R ++ ++M + D V +L Sbjct: 277 APVFVSKLRPLFVTEGDNVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDF-DGRVCSL 335 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 + E +D G + CV N+AG A S+ EL V+ Sbjct: 336 FLSEADCKDKGVYNCVITNSAGSAFSSAELQVD 368 Score = 72.9 bits (171), Expect = 9e-11 Identities = 66/348 (18%), Positives = 131/348 (37%), Gaps = 17/348 (4%) Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA--DVEM 1373 +P+ W N I ++ + D ++ L ++ ++ DAG Y+ N G A EM Sbjct: 211 EPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTAEM 270 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 V + P K L + N+ W + T+ +Y T W + Sbjct: 271 TVNKREAPVFVSKLRPLFVTEGD-NVSWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFD 329 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 + + N + +S + K K P V + + ++ Sbjct: 330 GRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDK-----KANKPKVIEKMNDVQ 384 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXY 1548 T + F G+P+P+VTWYR+ K++ + +R Y Sbjct: 385 TVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGDRYSLTITDTKLVDTGTY 444 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVIT--ISNEDIKQKHKVGDEWLVT--AVIEGIPPPEV 1604 KC+A N+ G++ + + ++++ ++++K+ V + + + G P P + Sbjct: 445 KCVATNEGGKITSRGDLDVRERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTI 504 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 +WYK+G + + + + I ++ + YT EASN G Sbjct: 505 VWYKDGEMVRDVRRFEIRSRGDIYTFATYSASAEDAGTYTCEASNKLG 552 Score = 68.5 bits (160), Expect = 2e-09 Identities = 53/238 (22%), Positives = 96/238 (40%), Gaps = 15/238 (6%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 +Q++K + ++ A N I A T E + K ++P L+ + +++ Sbjct: 242 LQDIKIKDAGQYECIASNP--IGKAFCTAE----MTVNKREAPVFVSKLRPLFVTEGDNV 295 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTA---KATYENRXXXXXXXXXX-XXXXXYKCIAFND 1555 C G+P+P V WYRD + L+ K ++ R Y C+ N Sbjct: 296 SWMCKVAGMPRPTVEWYRDNQPLRADTRWKMDFDGRVCSLFLSEADCKDKGVYNCVITNS 355 Query: 1556 HGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK 1612 G +S + + +K P + D++ G E G+P PEV WY+N K Sbjct: 356 AGSAFSSAELQVDKKANKPKVIEKMNDVQTVE--GTEARFDVRFSGLPRPEVTWYRNSIK 413 Query: 1613 LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 + N+ ++++ + I + K + Y A+N G + L V ++ PE Sbjct: 414 VRNESRFHLSEDGDRYSLTITDTKLVDTGTYKCVATNEGGKITSRGDLDVRERQFAPE 471 Score = 64.5 bits (150), Expect = 3e-08 Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 14/205 (6%) Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-N 1531 + K +PT L+ I +D +L+C G PQP+V W+RD +K + KA+Y+ N Sbjct: 10 QKKGDTPTFMSKLEPIEITEGDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGN 69 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK---------PVITISNEDIKQ 1582 YKC+ N+ G V + V + +K P+ Sbjct: 70 VSALTVKEAELDDDGVYKCVVTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPL 129 Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 + +V V+ + G P P V W+KNG +L + K I + + I + + Sbjct: 130 EIQVRQPVEVSYHVRGRPKPTVTWWKNGKELRDGKHVEIRSGGTYHTLYILRSEEEDAGS 189 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS 1667 Y A N G++ ++V ++PS Sbjct: 190 YKCLARNDVGSAERLFEVQV-EEPS 213 Score = 61.7 bits (143), Expect = 2e-07 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 1/97 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 ++++ P +EK+ T +G+ +F+ + G PRP++TW+R + ++ F + D D Sbjct: 368 DKKANKPKVIEKMNDVQTVEGTEARFDVRFSGLPRPEVTWYRNSIKVRNESRFHLSEDGD 427 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +L I + D GT+ CVA N G +S +L V Sbjct: 428 RY-SLTITDTKLVDTGTYKCVATNEGGKITSRGDLDV 463 Score = 55.2 bits (127), Expect = 2e-05 Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 4/118 (3%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEK--LRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 ++ K D + V +K E+ APIF EK L P V+ V G P+P +TW++ Sbjct: 97 VSSKAD-VTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWK 155 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 ++ + ++ TL I EDAG++ C+A+N G A E+ VE P Sbjct: 156 NGKELRDGKHVEIR-SGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEP 212 Score = 48.8 bits (111), Expect = 0.002 Identities = 36/169 (21%), Positives = 66/169 (39%), Gaps = 8/169 (4%) Query: 1508 VPQPKVTWYRDGKKL---KTAKATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGEV--ET 1561 V +P VTWYR+ ++ ++ T++ Y+CIA N G+ Sbjct: 209 VEEPSVTWYRNKNEIVPDGRSRTTFDGETYKLILQDIKIKDAGQYECIASNPIGKAFCTA 268 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 V ++ PV + W+ + G+P P V WY++ L D + + Sbjct: 269 EMTVNKREAPVFVSKLRPLFVTEGDNVSWM--CKVAGMPRPTVEWYRDNQPLRADTRWKM 326 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 + + + E Y +N+AG++ L+V K +KP+ Sbjct: 327 DFDGRVCSLFLSEADCKDKGVYNCVITNSAGSAFSSAELQVDKKANKPK 375 Score = 47.2 bits (107), Expect = 0.005 Identities = 26/89 (29%), Positives = 41/89 (46%), Gaps = 4/89 (4%) Query: 505 EQSMAPIFV---EKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 E+ AP F E P + + F+ +V G P P I W++ +++ + F++ Sbjct: 465 ERQFAPEFYGDDELKEPVVVQESDAINFKVRVRGKPVPTIVWYKDGEMVRDVRRFEIRSR 524 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAG 590 D + T EDAGT+TC A N G Sbjct: 525 GD-IYTFATYSASAEDAGTYTCEASNKLG 552 Score = 44.0 bits (99), Expect = 0.046 Identities = 24/109 (22%), Positives = 53/109 (48%), Gaps = 3/109 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 GD++ ++ + G P PEV W+++ ++ + + + S + +KE + Y Sbjct: 30 GDDFQLSCNVTGRPQPEVQWFRDEVLIKPSRRFKASYDGNVSALTVKEAELDDDGVYKCV 89 Query: 1647 ASNTAG--TSSVEVT-LKVYDKPSKPEGPVIMREISRESVTIEWKPPLD 1692 +N G +S +VT LK + +P + P+ + E + I+ + P++ Sbjct: 90 VTNNFGSVSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVE 138 Score = 42.7 bits (96), Expect = 0.11 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 8/126 (6%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKP--LKNITTEPNEDIELTCIFGGVPQPKVTWYRD 1518 +S ++ T K ++ + +P E+ L+ + + + +E++ G P+P VTW+++ Sbjct: 97 VSSKADVTVLKKHLRPERDYAPIFEEKQFLEPLEIQVRQPVEVSYHVRGRPKPTVTWWKN 156 Query: 1519 GKKLKTAKATYENRXXXXXXX-----XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 GK+L+ K E R YKC+A ND G E V +++ V Sbjct: 157 GKELRDGKHV-EIRSGGTYHTLYILRSEEEDAGSYKCLARNDVGSAERLFEVQVEEPSVT 215 Query: 1574 TISNED 1579 N++ Sbjct: 216 WYRNKN 221 >UniRef50_O94856 Cluster: Neurofascin precursor; n=64; Euteleostomi|Rep: Neurofascin precursor - Homo sapiens (Human) Length = 1347 Score = 126 bits (303), Expect = 9e-27 Identities = 90/320 (28%), Positives = 149/320 (46%), Gaps = 24/320 (7%) Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 +Q V G D+LLEC +P PDIAW KG ++ D+ + + L+ITNV Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDK-------AKFENFNKALRITNVS 307 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + G Y +A N+ G I +++K P ++ K++I+ GE L + GN Sbjct: 308 EEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGN 363 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENSEGIAETSAVI 820 P+PT+ W N +P+++ P + + TI+ + ++ VY N G +A + Sbjct: 364 PKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFV 423 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 +V + P + R Q I V +L +P+P++ W++N + S Sbjct: 424 SVLD-----VPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQ---GSNLDG 475 Query: 881 QNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 N+ EN L I + E D G Y CVA+N GK+ + +V ++V+ T + + + Sbjct: 476 GNYHVYENGSLEIKMIRKE-DQGIYTCVATNILGKAEN--QVRLEVKDPTRIYRMPEDQV 532 Query: 940 TEEGKTVILECQTSHTVSTK 959 G TV LEC+ H S K Sbjct: 533 ARRGTTVQLECRVKHDPSLK 552 Score = 101 bits (242), Expect = 2e-19 Identities = 121/520 (23%), Positives = 205/520 (39%), Gaps = 38/520 (7%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXX---XXXXXXXX 1545 KN+ P ED L C G P+P V W +G+ L++A Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C N+HG + + V + P +S + + + + + G P P + Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLR 463 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+KNG D N E S + IK +++ YT A+N G + +V L+V D Sbjct: 464 WFKNGQGSNLDGG-NYHVYENGS-LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDP 521 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPL-DDGGLELTKYAIEKHEP--DNNRWIKVAD---- 1718 P +++R T++ + + D L+LT ++ EP NR K D Sbjct: 522 TRIYRMP--EDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTI 579 Query: 1719 ---VDRDVETY-CI--QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772 +RD +Y C+ +L+++ + + + + L + P K D P Sbjct: 580 FGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALP---KGRPDRP----R 632 Query: 1773 XXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK----QEGKKWKXXXXXXXXXARIQK 1828 + SV +TW P + N SPI DY V+ + Q G + + + Sbjct: 633 DLELTDLAERSVRLTWIPGDAN-NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLR 691 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 LS YQFR+ A NE+G+S P ++ P S P + + ++ + WT Sbjct: 692 LSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGA-PPESNPGDVKGEGTRKNNMEITWTP 750 Query: 1889 PESNGG-SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 + P YI++++ + + VTV GS + + EI R+ AEN G Sbjct: 751 MNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEI--RVQAENDFG 808 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 E +SV P +++R++ S + W Sbjct: 809 KG--PEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQW 846 Score = 69.3 bits (162), Expect = 1e-09 Identities = 76/303 (25%), Positives = 123/303 (40%), Gaps = 31/303 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV---PDENISVAIESDMHM 690 P + +PK + G D L CR P+P + W+ GE + P+ N VA ++ Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT---- 392 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQG 749 + + T + Y N G + + PP+++ P +I V Sbjct: 393 --IIFRDTQISS--RAVYQCNTSNEHGYLLANAFVSVLD---VPPRMLSPRNQLIRVILY 445 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L G+P PT+ W KN + + +K + +D+G+YT A N Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT--W 866 G AE + V++PT I R E V +GT ++L RV +P +T W Sbjct: 506 ILGKAENQVRLEVKDPTR--------IYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +++E + I E+ L I V +E D G Y CVAS + A +T+ + Sbjct: 558 LKDDEPLY----IGNRMKKEDDSLTIFGV-AERDQGSYTCVASTELDQDLAKAYLTVLAD 612 Query: 927 KVT 929 + T Sbjct: 613 QAT 615 Score = 67.7 bits (158), Expect = 3e-09 Identities = 132/604 (21%), Positives = 220/604 (36%), Gaps = 57/604 (9%) Query: 633 PPTFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMH 689 PPT +K+ K VD +IL+EC P P W I D +S+ S Sbjct: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + + + EG Y A N+ G A S I L++ P + ++P ++V++ Sbjct: 100 VI--DFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP---VVVQE 154 Query: 749 GESVILSAQ-VVGNPRPTITWCKNN-KPV---KALPTKSDGDTHSITILKPKKVKDEG-- 801 G + L G P P I W ++ +P+ K + +GD + ++ D Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCN 214 Query: 802 -----VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 +T++ +N T V+T E V + L Sbjct: 215 ARFHFTHTIQQKN----PFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIA 270 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + P P I WY+ + + +NF N L ITNV SE DSG+Y C+ASN G Sbjct: 271 SGVPTPDIAWYKKGGDLPSDKAKFENF---NKALRITNV-SEEDSGEYFCLASNKMGSIR 326 Query: 917 HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHRE 974 H +++ V+ + K+ G+ L C+ + + +W N + + Sbjct: 327 H--TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIR-KLQDFEVK 1029 +E V +C ++ + + V + P + + Q V Sbjct: 385 -NREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVI 443 Query: 1030 EKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 + L+ S + W ++G+ Y + G + IR D+G Y+ Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRK---EDQGIYT 500 Query: 1089 CILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKD 1142 C+ + AE V V+ P I ++Q +G E + +L V W KD Sbjct: 501 CVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560 Query: 1143 GSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINF 1198 + N ++ D L I+ D G Y+C E+ A LTV Sbjct: 561 DEPLYIGNRMKKEDD----SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATP 616 Query: 1199 TLRL 1202 T RL Sbjct: 617 TNRL 620 Score = 62.9 bits (146), Expect = 9e-08 Identities = 117/589 (19%), Positives = 215/589 (36%), Gaps = 45/589 (7%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 L C F G P P + W+++G+ Y Y C+A N G+ Sbjct: 450 LDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509 Query: 1559 VETSCVVGIQQKPVITISNED--------IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 E + ++ I ED ++ + +V + + + + E ++ N Sbjct: 510 AENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNR 569 Query: 1611 NKLENDKE--YNITTKEKTSV--IRIKELKRSHSSKY-TIEASNTAGTSSVEVTLKVYDK 1665 K E+D + + +++ S + EL + + Y T+ A T+ + K + Sbjct: 570 MKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPK--GR 627 Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR--WIKVADVDRDV 1723 P +P + + +++ SV + W P D +T Y ++ E W + V Sbjct: 628 PDRPRD-LELTDLAERSVRLTWIPG-DANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSV 685 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNE 1782 + + +L+ Y FRVIA N VG S +L SE +T+ P Sbjct: 686 NS-AVLRLSPYVNYQFRVIAINEVGSSHPSLPSER--YRTSGAPPESNPGDVKGEGTRKN 742 Query: 1783 SVYITWFPSEKNGG-SPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRI 1839 ++ ITW P P + Y V+ ++ + W + + + Y+ R+ Sbjct: 743 NMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYV-VGQTPVYVPYEIRV 801 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N+ G P + I P + P V S +++L+W S+ + Sbjct: 802 QAENDFGKG-P-EPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSD---TVQG 856 Query: 1900 YIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEI--IFRISAENTVGVSLPTESQ 1955 + E++ + S K + V + + + + +F S V + Sbjct: 857 QLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGD 916 Query: 1956 SVRLE-KHATVP-SPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNI--AIRDVT 2009 R E K T P P+AP R+ N+ + W PE G ++GY + + T Sbjct: 917 GPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGI-MIGYTLKYVAFNGT 975 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 K V N KF ++ Y + AR ++G E + + P Sbjct: 976 KVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1024 Score = 60.1 bits (139), Expect = 7e-07 Identities = 146/705 (20%), Positives = 255/705 (36%), Gaps = 79/705 (11%) Query: 828 ENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 E +PP + ++ V + I + NP PS W RN+ + ++ + Sbjct: 36 ELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRR 95 Query: 887 NIELVI---TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT-FVKHLQKSYETEE 942 + LVI + E G+Y+C A N G + R+ + V K + K +E Sbjct: 96 SGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSN-RIRLQVSKSPLWPKENLDPVVVQE 154 Query: 943 GKTVILECQTSHTVSTK---WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV-IK 998 G + L+C + + W + E D R + +G D+ Sbjct: 155 GAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKR--VSQGHNGDLYFSNVMLQDMQTDYS 212 Query: 999 C--------IVKDQETSTMLV-----VKETIPEFI----RKLQDFEVKEKDVAILEVEIN 1041 C ++ + T+ V V E P F+ ++ D+ + + Sbjct: 213 CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272 Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 T D+ W + G + K K++ + L I N S D GEY C+ ++ + T Sbjct: 273 VPTPDIAWYKKGGDLPSDKAKFE----NFNKALRITNVSEEDSGEYFCLASNKMGSIRHT 328 Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157 + V+ P + +N + G V+W +G +Q S + Sbjct: 329 ISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ-SAPPNPNRE 387 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAILTVEEPSINFTLRLPEFILVPA 1210 + D + Y C N + ++L V ++ +L IL Sbjct: 388 VAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNR 447 Query: 1211 NTDAYLTVEIPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 P TL W+K D + + + +IRK +DQ YTCV Sbjct: 448 TRLDCPFFGSPIPTL--RWFKNGQGSNLDGGNYHVYENGSLEIKMIRK---EDQGIYTCV 502 Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNS 1325 + K+ ++++EV + P +I + +RG+ V L V + + W+ + Sbjct: 503 ATNILGKAENQVRLEVKD-PTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDD 561 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-DKPSP- 1383 + + K DS LTI V D G Y + +T+L D+ +P Sbjct: 562 EPLYIGNRMKKEDDS----LTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPT 617 Query: 1384 ----------PGKPNILEIDS---SSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWI 1428 P +P LE+ S+ + W P + NS I YVV+++E W Sbjct: 618 NRLAALPKGRPDRPRDLELTDLAERSVRLTWI-PGDANNSPITDYVVQFEEDQFQPGVWH 676 Query: 1429 S-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 K +++ L +Y+FR A+NEV S S +E Y+ Sbjct: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYR 721 Score = 59.7 bits (138), Expect = 9e-07 Identities = 79/403 (19%), Positives = 153/403 (37%), Gaps = 24/403 (5%) Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 PP I +++ + ++ + + + P P+ W NS+ K + S+ +S +L Sbjct: 40 PPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTL 99 Query: 1346 TIK-----KVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKPNILEI---DSSS 1396 I + E + G Y+ N G A + + + P P K N+ + + + Sbjct: 100 VIDFRSGGRPEEYE-GEYQCFARNKFGTALSNRIRLQVSKSPLWP-KENLDPVVVQEGAP 157 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSYRFRA 1453 + + + P + I + + I + +S + + + +Q+++T+ S R Sbjct: 158 LTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARF 217 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP---NEDIELTCIFGGVPQ 1510 + + I + T + ++P+ P +++ D+ L CI GVP Sbjct: 218 HFTHT--IQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT 275 Query: 1511 PKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 P + WY+ G L + KA +EN Y C+A N G + + V ++ Sbjct: 276 PDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA 335 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 P +E G++ + G P P V W NG L++ N + Sbjct: 336 APYWL--DEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPP-NPNREVAGDT 392 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 I ++ + S + Y SN G + V D P + P Sbjct: 393 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 435 Score = 52.4 bits (120), Expect = 1e-04 Identities = 68/267 (25%), Positives = 110/267 (41%), Gaps = 28/267 (10%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923 P +PR+ +++ RSV L W ++N SPIT+Y+++F+ + + W GSV+ Sbjct: 628 PDRPRDLELTDLAERSVRLTWIPGDAN-NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVN 686 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTA-PLEIRMVGS-- 1980 + + FR+ A N VG S P S+ E++ T +PP + P +++ G+ Sbjct: 687 S-AVLRLSPYVNYQFRVIAINEVGSSHP----SLPSERYRTSGAPPESNPGDVKGEGTRK 741 Query: 1981 NIVMTSWGTP--EWDGGAPLLGYNIA-IRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTY 2037 N + +W TP P L Y + R T+ W V V ++ + Y Sbjct: 742 NNMEITW-TPMNATSAFGPNLRYIVKWRRRETREAW---NNVTVWGSRYVVGQTPVYVPY 797 Query: 2038 MIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREH 2097 IR+ A N+ G + EP VI G D TEV W R + Sbjct: 798 EIRVQAENDFG-----KGPEPESVIGYSGE--DYPRAAPTEVKVRVMNSTAISLQWNRVY 850 Query: 2098 N--MDADIRSYARGSLLRRDEYFFRIW 2122 + + +R Y R R +W Sbjct: 851 SDTVQGQLREY-RAYYWRESSLLKNLW 876 Score = 39.5 bits (88), Expect = 0.99 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC G P P I W+++ + PS + +++ N A L I V ED+G + C Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDL-PSD--KAKFENFNKA-LRITNVSEEDSGEYFC 316 Query: 584 VAKNAAGFASSTTELIVEA 602 +A N G T + V+A Sbjct: 317 LASNKMGSIRHTISVRVKA 335 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 3/76 (3%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + +C G P P + WF+ + D Y+ +N +L I+ + ED G +TCVA N Sbjct: 449 RLDCPFFGSPIPTLRWFKNGQ--GSNLDGGNYHVYEN-GSLEIKMIRKEDQGIYTCVATN 505 Query: 588 AAGFASSTTELIVEAP 603 G A + L V+ P Sbjct: 506 ILGKAENQVRLEVKDP 521 Score = 37.9 bits (84), Expect = 3.0 Identities = 28/110 (25%), Positives = 43/110 (39%), Gaps = 4/110 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE- 1924 PS PR F V + ++ L+W PE G I Y +++ G K + S ++ Sbjct: 932 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMI-GYTLKYVAFNGTKVGKQIVENFSPNQT 990 Query: 1925 -HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT-VPSPPTAP 1972 ++ F +SA VG +S AT +PPT P Sbjct: 991 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAPPTLP 1040 Score = 37.1 bits (82), Expect = 5.3 Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 5/88 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS--VKNITKTQT 1438 PS P + + + + +IN+ WD PE+ N +I Y ++Y + T+ V+N + QT Sbjct: 932 PSAPRRFRVRQPNLETINLEWDHPEHP-NGIMIGYTLKYVAFNGTKVGKQIVENFSPNQT 990 Query: 1439 --SIQNLKTNSSYRFRAYAVNEVDISDA 1464 ++Q S YRF A +V +A Sbjct: 991 KFTVQRTDPVSRYRFTLSARTQVGSGEA 1018 >UniRef50_Q6IDE9 Cluster: LP21844p; n=2; Sophophora|Rep: LP21844p - Drosophila melanogaster (Fruit fly) Length = 1006 Score = 125 bits (302), Expect = 1e-26 Identities = 175/829 (21%), Positives = 327/829 (39%), Gaps = 77/829 (9%) Query: 648 GSDILLECRLVAIPEP--DIAWLFKGEEIV-PDEN------ISVAIESDMHMYCSVLKIT 698 G+ L++C + P +A +GEEI+ PD + + +A D+++ SV Sbjct: 152 GNSALIKCAIPEYVRPYVRVASWHRGEEILLPDLSDVAGRYVVLAASGDLYVR-SVRSED 210 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSA 756 + KF +N E + S ++L++K K P +P+ + V +G V L Sbjct: 211 GLMKFS--CLVTNTLNGERQRSDAVMLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPC 268 Query: 757 QVVGNPRPTITWCKNNKPVKALPTKSDGD---THSITILKPKKVKDEGVYTLKAENSEGI 813 + GNP P TW + + P S + ++ ++K +D G + +A N G Sbjct: 269 NIQGNPFPIFTWYRVSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGE 328 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 ++V + P + I V GT T + + +I W N + + Sbjct: 329 QRIEIRLSVNSYVSVHILPQVQI-------VNSGGTANFNCTTTGSAIDAIDWLHNGKPL 381 Query: 874 SPSETITQNFDG----ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + +T D L++ NV D G Y+C+ N + A + + + V Sbjct: 382 QANNALTTGRDNIRFLSKSSLLVQNVGRR-DRGVYQCLVENQRASAQAMAELKLG-DTVP 439 Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEIS--GMDHREIIQE------G 979 + + G + L+C S + + W + + I + HR I + Sbjct: 440 ELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGD 499 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKLQDFE-VKEKDVAIL 1036 D G+ KC+ + S + + P ++R + + V +D+ + Sbjct: 500 VISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGPIKAVAGEDIIVH 559 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV-HDEGEYSCILRD-- 1093 + WE+ + + N Y+ +L I+N D+G Y+CI+R Sbjct: 560 CPFAGYPVEQIRWEKAHQELTTS-NHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRA 618 Query: 1094 -ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFS 1149 E ++ + V PP I + + +G +A ++ GD + W KD S I S Sbjct: 619 GEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPSS 678 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-PEFILV 1208 I + L D +G+Y+C N+ T E +R+ P + Sbjct: 679 LQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAKVNYTAE-----LQVRVAPRWRYE 733 Query: 1209 PANTDAYL--TVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTED 1261 P +T L T+ I E +TW+K + + ++ F +S ++ +L++ T++ Sbjct: 734 PMDTAIMLGNTISINCEAEGYPIPTITWFKGQG--KGSKDFKPLS-MRNHSLLLNLATDN 790 Query: 1262 DQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 D+ Y C + A +++ V E P + R +R VTL + Sbjct: 791 DEGYYMCQATNEIGAGLKKTIRINVNE-PARFEQSARNISSRRNDPVTLDCHAKGDEPIT 849 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKS-----ASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 W N+ I + K+ + LTI + D+G+Y+ EN G A+ + Sbjct: 850 IGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQII 909 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 + + ++P P I E+ S ++ + W P + GNS ++ Y+V+YQ + Sbjct: 910 FLAVQERPDTPSHLEIFEVGSRTVKLSWRRPFD-GNSPVLSYLVQYQAL 957 Score = 84.6 bits (200), Expect = 3e-14 Identities = 135/607 (22%), Positives = 241/607 (39%), Gaps = 64/607 (10%) Query: 627 DILEGIPPTFSKKPKAQ-YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 ++ + + P ++KP + +V+ G+D+ L C + P P W V D I Sbjct: 239 ELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYR-----VSDSAALYPIP 293 Query: 686 SDMHMYCS--VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPL 741 S + S +L I N + G + A N+ GE + I L + + PQV Sbjct: 294 SSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQV---- 349 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGD---THSITILKPK 795 IV G + + G+ I W N KP++A L T D + S +++ Sbjct: 350 --QIVNSGGTANFNCTTTGSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNV 407 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 +D GVY EN A+ A + + + E I F E V+ I L Sbjct: 408 GRRDRGVYQCLVENQRASAQAMAELKLGDTVPE------LIYTFIEQNVRPGPLISLKCS 461 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIEL---VITNVD-SEI---DSGDYKCVA 908 + +P P W +++ I + G+ +++ VI++++ S + D G YKCVA Sbjct: 462 ASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVA 521 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ-TSHTV-STKWYHNKKE 966 SNS G H AR ++V +V+ + + G+ +I+ C + V +W +E Sbjct: 522 SNSMGSVQHSAR--LNVYGPPYVRAI-GPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQE 578 Query: 967 ISGMDHREI--IQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIR 1021 ++ +H E+ + +G D G+ CIV+ +E + + P I Sbjct: 579 LTTSNHYELASVADG-GQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIE 637 Query: 1022 KLQ-DFEVKEKDVAILEVEINSETADVV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 + ++E A + ++S + W++D I P + +K L ++ Sbjct: 638 PFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSI-PSSLQITEKKEEFYSLLVFKD 696 Query: 1079 TSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 S G+Y+C + + T V + P + + GN + E +G Sbjct: 697 ISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCE-AEGYP 755 Query: 1136 L--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAI 1188 + + WFK G + L++ + L + +D G Y C+ N K T Sbjct: 756 IPTITWFK-GQGKGSKDFKPLSM--RNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIR 812 Query: 1189 LTVEEPS 1195 + V EP+ Sbjct: 813 INVNEPA 819 Score = 70.5 bits (165), Expect = 5e-10 Identities = 130/664 (19%), Positives = 237/664 (35%), Gaps = 48/664 (7%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130 L I+N D G++ C ++ + + V + Q Q VN G A F Sbjct: 305 LLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTT 364 Query: 1131 TKGDAL--VRWFKDGSEIQFSNHIQLTIDG----KKQKLKIYDCDLDDAGEYSCEVGNSK 1184 T G A+ + W +G +Q +N + D K L + + D G Y C V N + Sbjct: 365 T-GSAIDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVENQR 423 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-----DVTWYKKKSVIEDT 1239 +A + E + T+ + + N + + W I D Sbjct: 424 ASA-QAMAELKLGDTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDV 482 Query: 1240 E--------KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 +F +S L I DD Y CV ++ + + + + P V Sbjct: 483 SLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYV 542 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 + G D+ + + +P W + + H + + + L IK VE Sbjct: 543 RAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVE 602 Query: 1352 -NTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 D GIY + + G D+++NV P P L+ + C ++ Sbjct: 603 PGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEGGRAQITC---AVSS 659 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 G+ I + +++ D++ S++ IT+ + +L R S+A+ Sbjct: 660 GDMPIYF---SWKKDDSSIPSSLQ-ITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAK 715 Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAK 1526 Y + + ++ +P+ N I + C G P P +TW++ GK K K Sbjct: 716 VNYTAEL-QVRVAPRWRYEPMDTAIMLGNT-ISINCEAEGYPIPTITWFKGQGKGSKDFK 773 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHK 1585 Y C A N+ G ++ + + + + S +I + Sbjct: 774 PLSMRNHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRR- 832 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNI----TTKEKTSVIRIKELKRSHS 1640 D + +G P + W +N +++ N+ ++I T K S + I R S Sbjct: 833 -NDPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAEMKTEKGVDSQLTIGHSDRHDS 891 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 Y A N G + + L V ++P P I E+ +V + W+ P DG + Sbjct: 892 GVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIF-EVGSRTVKLSWRRPF-DGNSPVLS 949 Query: 1701 YAIE 1704 Y ++ Sbjct: 950 YLVQ 953 Score = 59.7 bits (138), Expect = 9e-07 Identities = 100/471 (21%), Positives = 173/471 (36%), Gaps = 50/471 (10%) Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYENRX 1533 + P + + I EDI + C F G P ++ W + ++L T+ + + Sbjct: 536 VYGPPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQ 595 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y CI + GE + + PVI K + G + Sbjct: 596 LVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFP-KNLQEGGRAQIT 654 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 AV G P W K+ + + + + +E S++ K++ HS KYT ASN A Sbjct: 655 CAVSSGDMPIYFSWKKDDSSIPSSLQITEKKEEFYSLLVFKDISARHSGKYTCYASNAAA 714 Query: 1653 TSSVEVTLKVYDKPS---KPEGPVIMR----EISRESV-----TIEWKPPLDDGGLELTK 1700 + L+V P +P IM I+ E+ TI W G + Sbjct: 715 KVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGKGSKDFKP 774 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE---NCEYMFRVIAQNPVGFSEALESEP 1757 ++ H + + +A D D Y Q NE + R+ P F ++ + Sbjct: 775 LSMRNH----SLLLNLA-TDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARN-- 827 Query: 1758 IVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXX 1817 I + + P +E + I W ++ NG + +++ I E K K Sbjct: 828 --ISSRRNDPVTLDCHAKG----DEPITIGW--TQNNGRIDLNNFRFSIA-EMKTEKGVD 878 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 I + + +R A N PY ++I P P + + E Sbjct: 879 SQLT----IGHSDRHDSGVYRCIAEN------PYGRAEQIIFLAVQERPDTPSHLEIFEV 928 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSVHEHCI 1927 SR+V L W P +G SP+ +Y+++++ +K +S + GG + H I Sbjct: 929 GSRTVKLSWRRP-FDGNSPVLSYLVQYQALKYLQSHGSLAAAGGDWNGHVI 978 Score = 58.4 bits (135), Expect = 2e-06 Identities = 71/295 (24%), Positives = 119/295 (40%), Gaps = 34/295 (11%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + + EG + C + + P K + +P S+ I + Sbjct: 633 PPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSIPS---SLQITEKKEEFY 689 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 S+L ++ G YT A N + + L+++ P EP+ + I+ G ++ Sbjct: 690 SLLVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVA---PRWRYEPMDTAIML-GNTI 745 Query: 753 ILSAQVVGNPRPTITWCKN----NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 ++ + G P PTITW K +K K L ++ HS+ +L DEG Y +A Sbjct: 746 SINCEAEGYPIPTITWFKGQGKGSKDFKPLSMRN----HSL-LLNLATDNDEGYYMCQAT 800 Query: 809 NSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G + I V EP F + I+ + + L + +I W Sbjct: 801 NEIGAGLKKTIRINVNEPAR-------FEQSARNISSRRNDPVTLDCHAKGDEPITIGWT 853 Query: 868 RNNEII-------SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 +NN I S +E T+ G + +L I + D DSG Y+C+A N G++ Sbjct: 854 QNNGRIDLNNFRFSIAEMKTEK--GVDSQLTIGHSDRH-DSGVYRCIAENPYGRA 905 Score = 48.4 bits (110), Expect = 0.002 Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 17/236 (7%) Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 H + T A++ + P + +P + G+ I + C P P I Sbjct: 701 HSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTIT 760 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 W FKG+ + +++ + H L N EG Y A N G A L ++ Sbjct: 761 W-FKGQGKGSKDFKPLSMRN--HSLLLNLATDN----DEGYYMCQATNEIG-AGLKKTIR 812 Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV-------KALP 779 I E P + + +++ R+ + V L G+ TI W +NN + Sbjct: 813 INVNE--PARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNGRIDLNNFRFSIAE 870 Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 K++ S + D GVY AEN G AE + V+E + + +F Sbjct: 871 MKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIF 926 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+T+ C+ EGYP P ITWF+ K S+DF+ ++ +L++ D G + C Sbjct: 742 GNTISINCEAEGYPIPTITWFKGQG--KGSKDFKPLSMRNH--SLLLNLATDNDEGYYMC 797 Query: 584 VAKNAAG 590 A N G Sbjct: 798 QATNEIG 804 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 3/96 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +V + P G + C GYP QI W + + S +++ D LV Sbjct: 539 PPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADG-GQLV 597 Query: 570 IREVFP-EDAGTFTCVAKNAAG-FASSTTELIVEAP 603 I+ V P D G +TC+ ++ AG A +L V +P Sbjct: 598 IKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSP 633 Score = 40.3 bits (90), Expect = 0.57 Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 5/105 (4%) Query: 506 QSMAPIFVEK-LRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQDFQMYYDD 562 +++AP +K + H G+ V C ++G P P TW+R +A + P Q Sbjct: 242 KNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYRVSDSAALYPIPSSQRVILS 301 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + L+I+ DAG + C A N G L V + +S H Sbjct: 302 RTL--LLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVH 344 Score = 39.9 bits (89), Expect = 0.75 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY----------DDDNVATLVIREV 573 G + +C G P PQ W + +P D +++ D ++ L I V Sbjct: 453 GPLISLKCSASGSPPPQFAWLLDS---QPIMDVSLHHRFAIGQFVDMSGDVISHLNISHV 509 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 P+D G + CVA N+ G + L V P Sbjct: 510 RPDDGGLYKCVASNSMGSVQHSARLNVYGP 539 Score = 38.3 bits (85), Expect = 2.3 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 509 APIFVEKLR-PKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVA 566 +P +E + PK+ +G Q C V P +W + + I PS ++ + Sbjct: 632 SPPVIEPFKFPKNLQEGGRAQITCAVSSGDMPIYFSWKKDDSSI-PSSLQITEKKEEFYS 690 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 LV +++ +G +TC A NAA + T EL V Sbjct: 691 LLVFKDISARHSGKYTCYASNAAAKVNYTAELQV 724 Score = 36.7 bits (81), Expect = 7.0 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 23/123 (18%) Query: 1882 VTLKWTEPESNGGSPITNY---IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIF 1938 +T+ WT+ +NG + N+ I E KT KG +T+G S D ++ Sbjct: 848 ITIGWTQ--NNGRIDLNNFRFSIAEMKTEKGVD--SQLTIGHS---------DRHDSGVY 894 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL 1998 R AEN G + Q + L +P + LEI VGS V SW P +DG +P+ Sbjct: 895 RCIAENPYGRA----EQIIFLAVQERPDTP--SHLEIFEVGSRTVKLSWRRP-FDGNSPV 947 Query: 1999 LGY 2001 L Y Sbjct: 948 LSY 950 >UniRef50_UPI000066030F Cluster: Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).; n=2; Takifugu rubripes|Rep: Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein). - Takifugu rubripes Length = 1351 Score = 124 bits (299), Expect = 3e-26 Identities = 108/421 (25%), Positives = 171/421 (40%), Gaps = 16/421 (3%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVE 1724 P +P V EI R + + WKPP G L Y IEK W +V + Sbjct: 368 PGEPTN-VHASEIFRSYIVLSWKPPSPRGRAPLW-YVIEKCLAGTGAWQRVNTGIQLLAP 425 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXXIDNES 1783 Y + L + +Y FRV + N G SEA E + K LD VPS S Sbjct: 426 RYPVFDLQDGQKYQFRVYSVNMYGSSEASEPSESIQKVNLDGVPSAPGHVVATRN-SKSS 484 Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIY 1840 V++ W S+ ++ Y ++ + G K W R + L +Y FR+ Sbjct: 485 VFVQWEASKHPKN--LMGYYIDGRVVGAKDWFPCNHKPFKQNRFVVHGLVPGESYVFRVQ 542 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N G S I++ L PS P + S+TL W P+ GGS I Y Sbjct: 543 AVNVFGLSEESQESTPISVEPALATPSAPYGITMLNCDGSSITLAWKSPKHCGGSKINAY 602 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 I+ + V W ++ + ++++ E F++ A N GV LP+ Sbjct: 603 YIDKRDVDSLVWKEVNQEAVTERIFTVDSLIEGTFYEFKVQAANMAGVGLPSVPSLPMKC 662 Query: 1961 KHATVPSP-PTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 T+ P P L V S+ ++ W P + G + + GY + + + + + + Sbjct: 663 VAWTMEEPGPAYDLSFSEVRSHSLVFLWKAPVYYGMSAITGYYVDMAKKGLSEFETLNQE 722 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF--KVIPGEG---SHADEEPG 2074 V+ + L E +Y+ R+ A N +G+ +P E +P K +PG + DEE G Sbjct: 723 PVSHRYLQVTGLEEGQSYVFRVRAVNSVGVGKPSEVSDPVCAKALPGTKEIVASVDEETG 782 Query: 2075 E 2075 + Sbjct: 783 D 783 Score = 67.7 bits (158), Expect = 3e-09 Identities = 64/277 (23%), Positives = 112/277 (40%), Gaps = 34/277 (12%) Query: 1227 VTWYKKKSVIEDTE---KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK--STTKLKV 1281 V WYK+ ++ K+ + S +L+I +C D EY+ V ++ +T+K V Sbjct: 38 VKWYKEGVPVDPLSTPGKYKIESKYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATV 97 Query: 1282 EV---------------VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ-----PNDEW 1321 V V+ ++D+ G ++L+ P P +W Sbjct: 98 IVKSKKLFFLLCHSDVFVKLEVTLIDHFPVSFGVEGDSISLVCSMVVVPNLPNLPPLAQW 157 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-K 1380 + K++K K + S+ +A LT+ + D G+Y LR+ G + + + D Sbjct: 158 YRDDKLLKPNKFVEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDGSTEHSAYLFVSDAA 217 Query: 1381 PSPPGKP------NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-- 1432 PS G P +I+S + I W P + II Y V+ E + W+ + Sbjct: 218 PSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSDTWVQCNDSP 277 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + + + LK +Y FR AVN IS S ++ Sbjct: 278 VNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSD 314 Score = 65.7 bits (153), Expect = 1e-08 Identities = 73/299 (24%), Positives = 121/299 (40%), Gaps = 34/299 (11%) Query: 1499 IELTCIFGGVPQPKVTWYRDG---KKLKT-AKATYENRXXXXXXXXXX---XXXXXYKCI 1551 I+L C G P+P V WY++G L T K E++ Y + Sbjct: 24 IKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIESKYGVHSLVISRCAVSDTAEYSAV 83 Query: 1552 AFNDHGEVETSCVVGIQQKPVI-TISNEDIKQKHKVG--DEWLVTAVIEG---------- 1598 A N HG + V ++ K + + + D+ K +V D + V+ +EG Sbjct: 84 ATNSHGMATSKATVIVKSKKLFFLLCHSDVFVKLEVTLIDHFPVSFGVEGDSISLVCSMV 143 Query: 1599 -IP-----PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 +P PP WY++ L+ +K ++ + + + L + YT+ G Sbjct: 144 VVPNLPNLPPLAQWYRDDKLLKPNKFVEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDG 203 Query: 1653 TSSVEVTLKVYDK-PS---KPEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKH 1706 ++ L V D PS P P+ ++ +I+ + V I WKPP + Y +++ Sbjct: 204 STEHSAYLFVSDAAPSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRC 263 Query: 1707 EPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 E ++ W++ D +V Y + L Y FRV A N G S V TALD Sbjct: 264 EAGSDTWVQCNDSPVNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSDKV--TALD 320 Score = 62.1 bits (144), Expect = 2e-07 Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 6/203 (2%) Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGS 1921 +T P +P N SE + L W P G +P+ Y+IE +W ++ T + Sbjct: 365 VTIPGEPTNVHASEIFRSYIVLSWKPPSPRGRAPLW-YVIEKCLAGTGAWQRVNTGIQLL 423 Query: 1922 VHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMVGS 1980 + + ++++ + FR+ + N G S +E S+S++ VPS P + R S Sbjct: 424 APRYPVFDLQDGQKYQFRVYSVNMYGSSEASEPSESIQKVNLDGVPSAPGHVVATRNSKS 483 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + V W + L+GY I R V W +F + L +Y+ R Sbjct: 484 S-VFVQWEASKHPKN--LMGYYIDGRVVGAKDWFPCNHKPFKQNRFVVHGLVPGESYVFR 540 Query: 2041 IYARNEIGLSEPLESDEPFKVIP 2063 + A N GLSE + P V P Sbjct: 541 VQAVNVFGLSEESQESTPISVEP 563 Score = 60.1 bits (139), Expect = 7e-07 Identities = 42/187 (22%), Positives = 83/187 (44%), Gaps = 10/187 (5%) Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 P+ + + K +K + ++ +VGG + ++ + DE ++ + G TE Sbjct: 153 PLAQWYRDDKLLKPNKFVEM-SVGGGAARLTLPHLAKDDEGLYTLRVFTKDG---STEHS 208 Query: 1956 SVRLEKHA--TVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + A +V P AP+ ++ + S+ V+ +W P AP++GY + + Sbjct: 209 AYLFVSDAAPSVAGAPGAPMSVKAYDINSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSD 268 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADE 2071 W++ VN K+ + L HTY R+ A N G+S P + KV + + +++ Sbjct: 269 TWVQCNDSPVNVCKYPVHGLKVGHTYHFRVRAVNSAGISRPSRKSD--KVTALDTAESEK 326 Query: 2072 EPGEQTE 2078 G + E Sbjct: 327 LQGTEEE 333 Score = 54.8 bits (126), Expect = 2e-05 Identities = 47/220 (21%), Positives = 92/220 (41%), Gaps = 23/220 (10%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +E P F+ LRP + + ++ C V+G PRP + W+++ + P Y + Sbjct: 1 DEVPKMPDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIES 60 Query: 564 --NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 V +LVI D ++ VA N+ G A+S +IV++ ++ Sbjct: 61 KYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATVIVKS------KKLFFLLCHSDVF 114 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE----PDIAWLFKGEEIVPD 677 +++ P +F EG I L C +V +P P +A ++ ++++ Sbjct: 115 VKLEVTLIDHFPVSFGV--------EGDSISLVCSMVVVPNLPNLPPLAQWYRDDKLLKP 166 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 +E + + L + ++ K EG YT+ ++G Sbjct: 167 NKF---VEMSVGGGAARLTLPHLAKDDEGLYTLRVFTKDG 203 Score = 52.4 bits (120), Expect = 1e-04 Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 22/205 (10%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT------KSDGDTHS 788 P I L+ V + + L V GNPRP + W K PV L T +S HS Sbjct: 7 PDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIESKYGVHS 66 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP------TEENAEPPLFINRFQEI 842 + I + V D Y+ A NS G+A + A + V+ + L + Sbjct: 67 LVISR-CAVSDTAEYSAVATNSHGMATSKATVIVKSKKLFFLLCHSDVFVKLEVTLIDHF 125 Query: 843 TVK---EKGTIKLVARVT-----RNPVPSITWYRNNEIISPSETITQNFDGENIELVITN 894 V E +I LV + N P WYR+++++ P++ + + G L + + Sbjct: 126 PVSFGVEGDSISLVCSMVVVPNLPNLPPLAQWYRDDKLLKPNKFVEMSVGGGAARLTLPH 185 Query: 895 VDSEIDSGDYKCVASNSAGKSSHGA 919 + + D G Y G + H A Sbjct: 186 LAKD-DEGLYTLRVFTKDGSTEHSA 209 Score = 49.6 bits (113), Expect = 0.001 Identities = 52/286 (18%), Positives = 108/286 (37%), Gaps = 8/286 (2%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435 L PS P +L D SSI + W P++ G S I Y ++ +++D+ W ++ + +T+ Sbjct: 565 LATPSAPYGITMLNCDGSSITLAWKSPKHCGGSKINAYYIDKRDVDSLVWKEVNQEAVTE 624 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494 ++ +L + Y F+ A N + S + K + T + P + + + Sbjct: 625 RIFTVDSLIEGTFYEFKVQAANMAGVGLPSVPSLPMKCVAWTMEEPGPAYDLSFSEVRSH 684 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXXXXXXXXXXXXYKC 1550 + ++ G+ + KK +T + ++ Sbjct: 685 SLVFLWKAPVYYGMSAITGYYVDMAKKGLSEFETLNQEPVSHRYLQVTGLEEGQSYVFRV 744 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 A N G + S V + + E + + GD +L E + +W KN Sbjct: 745 RAVNSVGVGKPSEVSDPVCAKALPGTKEIVASVDEETGDIYLSLEACEISETSKFVWSKN 804 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + ++T K +TS + + +Y++ ++T G S+ Sbjct: 805 YKPIGECPRVSVTAKGRTSRLTFTNPDKDDLGRYSVVVTDTDGVSA 850 Score = 47.6 bits (108), Expect = 0.004 Identities = 19/65 (29%), Positives = 37/65 (56%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 ++ C V G P P++TWF+ + ++ ++ +D A+LVI +V P+D+G ++ Sbjct: 1271 SLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINV 1330 Query: 586 KNAAG 590 +N G Sbjct: 1331 RNKYG 1335 Score = 46.8 bits (106), Expect = 0.007 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ-NFDG 885 +E + P FI + TV EK IKL V NP P + WY+ + P T + + Sbjct: 1 DEVPKMPDFIIALRPHTVWEKTPIKLFCTVQGNPRPIVKWYKEGVPVDPLSTPGKYKIES 60 Query: 886 E-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + + ++ + + D+ +Y VA+NS G ++ A V + +K+ F+ Sbjct: 61 KYGVHSLVISRCAVSDTAEYSAVATNSHGMATSKATVIVKSKKLFFL 107 Score = 46.8 bits (106), Expect = 0.007 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +T+ E+ ++ L V P P +TW++N + + +E FDG ++ N + DS Sbjct: 1264 VTIMEEKSLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDS 1323 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEK 927 G Y N G +T+ V K Sbjct: 1324 GKYSINVRNKYG--GEFVEITVSVYK 1347 Score = 45.2 bits (102), Expect = 0.020 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTIEASNT 1650 +T + G P PEV W+KN ++ +++ +T K + + I ++ S KY+I N Sbjct: 1274 LTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRNK 1333 Query: 1651 AGTSSVEVTLKVY 1663 G VE+T+ VY Sbjct: 1334 YGGEFVEITVSVY 1346 Score = 42.3 bits (95), Expect = 0.14 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P W N + + +HT+ + D K ASL I KV D+G Y + + N G VE+ Sbjct: 1282 PTPEVTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRNKYGGEFVEI 1341 Query: 1374 NVTI 1377 V++ Sbjct: 1342 TVSV 1345 Score = 41.1 bits (92), Expect = 0.33 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P P + EI S I + W P G + + +YV+E T W V + + Sbjct: 368 PGEPTNVHASEIFRSYIVLSWKPPSPRGRAPL-WYVIEKCLAGTGAWQRVNTGIQLLAPR 426 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +L+ Y+FR Y+VN S+ASE +E Sbjct: 427 YPVFDLQDGQKYQFRVYSVNMYGSSEASEPSE 458 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835 I+++ V I W P +PII Y V+ + G W + + L + TY Sbjct: 235 INSDYVLIAWKPPNIVNQAPIIGYFVDRCEAGSDTWVQCNDSPVNVCKYPVHGLKVGHTY 294 Query: 1836 QFRIYARNEIGTSLPYTSDDKIT 1858 FR+ A N G S P DK+T Sbjct: 295 HFRVRAVNSAGISRPSRKSDKVT 317 Score = 36.7 bits (81), Expect = 7.0 Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 4/102 (3%) Query: 731 EKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDT 786 EK +V+ L ++ + + +S+ L+ V G P P +TW KN + V + DG Sbjct: 1250 EKNRGRVVGGLPDVVTIMEEKSLSLTCTVWGEPTPEVTWFKNEQEVISNEHTRVTFDGGK 1309 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + ++ D G Y++ N G ++V + E+ Sbjct: 1310 FASLVINKVTPDDSGKYSINVRNKYGGEFVEITVSVYKHGEQ 1351 Score = 36.7 bits (81), Expect = 7.0 Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGN 1182 V WFK+ E+ + H ++T DG K L I DD+G+YS V N Sbjct: 1286 VTWFKNEQEVISNEHTRVTFDGGKFASLVINKVTPDDSGKYSINVRN 1332 >UniRef50_Q4RJ21 Cluster: Chromosome 1 SCAF15039, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF15039, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1702 Score = 123 bits (297), Expect = 5e-26 Identities = 162/720 (22%), Positives = 259/720 (35%), Gaps = 60/720 (8%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 +L V+ +P S + E LR T +G C+V P P ITW ++ +I P Sbjct: 865 QLTVYVRPRSNAEGPGSS-AEPLRMSVT-EGEDAILPCEVHSVPPPTITWAKER-LISP- 920 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------- 605 F + ++ I E D+G + CVA N AG + + L V P S Sbjct: 921 --FAPRHHPLPSCSMKILESKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGPRVM 978 Query: 606 ----DHGSEMTVXXXX----XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 H E+ ++E + P F+ + + ++ I C Sbjct: 979 KVQVGHPVELPCMVSGVPEPTLTWTRDVPPVVEVLEPPFNSPLQERVANQR--IAFPCPA 1036 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 +P+P I WL G+E+ +E V+I D ++L + +V G Y A N G Sbjct: 1037 KGLPKPVIRWLRNGQELTGNEP-GVSILEDG----TLLLLASVSPLDSGEYVCAAANDAG 1091 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 LK+ + S+++ Q S++ V G+P P ITW K PV A Sbjct: 1092 STERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSLV--CDVTGSPSPVITWYKEEMPVVA 1149 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 D L D G Y+ KA N G AE + V P Sbjct: 1150 SDNVQILDMGKTLRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGS-----G 1204 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 + I L +V P P+I WY++ + + + N + N ++ + Sbjct: 1205 SSHDTVAMVTQEISLECKVEGLPFPTIQWYKDRKQVFLGD---PNLEVTNRGQILRIKSA 1261 Query: 898 EI-DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT- 955 + D Y+C N+AGK S +++ V + G V LEC+ Sbjct: 1262 RLGDKARYQCSVMNTAGKESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVP 1321 Query: 956 -VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE 1014 + WY N + I + + GR K T + Sbjct: 1322 PPTVTWYRNGQAILSGRQTQYTERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDV 1381 Query: 1015 TIPEFIRKLQDFEVKEKDVA-----ILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKR 1068 +P I K D E+ V ILE E + W +DG ++ ++ E Sbjct: 1382 YLPPTI-KGDDAGPTERKVVLSASLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELG 1440 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPPEI--ITRLQNQKVNKGNK 1123 G K+ I + ++ D G Y C+ + EV V +PP I + + V + Sbjct: 1441 G---KIEISSATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHP 1497 Query: 1124 ATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 E + T +V W+KDG IQ ++ G Q+L + + D + C N Sbjct: 1498 LEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGG--QRLLVSRAQISDTARFQCVAAN 1555 Score = 89.8 bits (213), Expect = 7e-16 Identities = 104/450 (23%), Positives = 179/450 (39%), Gaps = 41/450 (9%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V C GYP P++ W +K S +M D L IR +D G + C Sbjct: 480 GDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPD----GMLAIRNTEQKDGGVYRC 535 Query: 584 VAKNAAGFASSTTELI-VEAPLSDHG-SEMTVXXXXXXXXXXXXADILEG------IPPT 635 +A N AG ++ + L +E+P+ ++ V + + P Sbjct: 536 LASNQAGTDATNSVLTYIESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAAPE 595 Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+++P D GS++ L C + P+P + W + ++ +P N S + L Sbjct: 596 FTREPSDTASDIGSNVTLWCLVRGYPDPQVTW--RRQDGLPPFNRPRTYGS-VTQSRRGL 652 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 T++ E Y A N G+ + + TG P P +V + Sbjct: 653 HFTHLWVEDEAVYVCEAHNHFGKIEAKARITV-TGLVLPVIARSPSVLSVVEDQPVTLPC 711 Query: 756 AQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + GNP P W N V + + + DG H ++ ++ G YT AEN G Sbjct: 712 VLLAGNPLPARQWLHNYGLVTTDQYVKVRKDGSLH----IERVRLDHVGDYTCLAENVVG 767 Query: 813 IAETSAVITVEE-PTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 + + + V PT ++ P +F E + L R P P ITW + + Sbjct: 768 LYNHTTTLNVYVIPTIQHG-PQVF-------NTIEGTPVTLPCRAIGVPSPEITWTKEGK 819 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 ++ +F ++ + N S +SG++ C+A+N+AG +S ++T+ V + Sbjct: 820 LLYLG---GPDFFLDSDGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNA 876 Query: 932 KHLQKSYE-----TEEGKTVILECQTSHTV 956 + S E EG+ IL C+ H+V Sbjct: 877 EGPGSSAEPLRMSVTEGEDAILPCEV-HSV 905 Score = 84.6 bits (200), Expect = 3e-14 Identities = 71/276 (25%), Positives = 117/276 (42%), Gaps = 19/276 (6%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 L +E DH + T + + PT P+ EG+ + L CR Sbjct: 745 LHIERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVIPTIQHGPQVFNTIEGTPVTLPCRA 804 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 + +P P+I W +G +++ ++SD ++ I + + G + +A N G Sbjct: 805 IGVPSPEITWTKEG-KLLYLGGPDFFLDSDGSLF-----INSPSGNESGEFICMATNAAG 858 Query: 718 EAS----LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 AS L + ++ ++ + P EPL+ M V +GE IL +V P PTITW K Sbjct: 859 HASRRVQLTVYVRPRSNAEGPGSSAEPLR-MSVTEGEDAILPCEVHSVPPPTITWAKERL 917 Query: 774 PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 P + S+ IL+ KV D G+Y A N G S +++V P P Sbjct: 918 ISPFAPRHHPLPSCSMKILE-SKVSDSGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGP- 975 Query: 834 LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 R ++ V ++L V+ P P++TW R+ Sbjct: 976 ----RVMKVQVGH--PVELPCMVSGVPEPTLTWTRD 1005 Score = 82.2 bits (194), Expect = 1e-13 Identities = 78/258 (30%), Positives = 111/258 (43%), Gaps = 41/258 (15%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATLVIREVFPEDA 578 +T +G+ V C+ G P P+ITW ++ ++ DF + D D +L I ++ Sbjct: 791 NTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDF--FLDSDG--SLFINSPSGNES 846 Query: 579 GTFTCVAKNAAGFASSTTELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 G F C+A NAAG AS +L V P S+ EG P S Sbjct: 847 GEFICMATNAAGHASRRVQLTVYVRPRSN----------------------AEG--PGSS 882 Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 +P V EG D +L C + ++P P I W K I P + S CS +KI Sbjct: 883 AEPLRMSVTEGEDAILPCEVHSVPPPTITWA-KERLISPFAPRHHPLPS-----CS-MKI 935 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 K G Y VA N G +L ++L + PP + + M V+ G V L Sbjct: 936 LESKVSDSGIYVCVASNIAGNLTLSVLLSVLV----PPSIQPGPRVMKVQVGHPVELPCM 991 Query: 758 VVGNPRPTITWCKNNKPV 775 V G P PT+TW ++ PV Sbjct: 992 VSGVPEPTLTWTRDVPPV 1009 Score = 80.2 bits (189), Expect = 6e-13 Identities = 112/575 (19%), Positives = 229/575 (39%), Gaps = 38/575 (6%) Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VEL 1105 W R+G+ + + + G + L + + S D GEY C +++ + E V + Sbjct: 1046 WLRNGQELTGNEPGVSILEDGTL--LLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNV 1103 Query: 1106 PPEIITRLQNQKVNK--GNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 PP+ ++ V+ + ++T + ++ W+K+ + S+++Q+ GK Sbjct: 1104 PPDFTDNEVSRNVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQILDMGKT-- 1161 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA-----ILTVEEPSINFTLRLPEFI-LVPANTDAYL 1216 L++ D D+G YSC+ N +A + + P+I + + + +V Sbjct: 1162 LRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISLEC 1221 Query: 1217 TVE-IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 VE +P T+ WYK + + + +++ + + L I+ D+ Y C +++ Sbjct: 1222 KVEGLPFPTIQ--WYKDRKQVFLGDPNLEVTN-RGQILRIKSARLGDKARYQCSVMNTAG 1278 Query: 1276 TTKLKVEV-VEFPPKIVDYEREYRIKR--GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 + V PP I + G+ VTL + + P P W N + I + Sbjct: 1279 KESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGR 1338 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNI 1389 T+ + + L I +V+ TDAG Y + + G + + + P+ G P Sbjct: 1339 QTQYT--ERGRFLKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTE 1396 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 ++ S+ I E ++ + + + + ++ + V + + I + + S Sbjct: 1397 RKVVLSASLILECEAGGRPPPSLTW-LKDGVPVRHSQSLRVLELGG-KIEISSATLSDSG 1454 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 R+ A + ++ E V+ IQ V + + T N +E+ C G P Sbjct: 1455 RYVCVATS---VAGEKEVKYDVTVLVPPFIQGAGV---ITHSTVIINHPLEMECQATGTP 1508 Query: 1510 QPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 P VTWY+DGK ++ + ++C+A N+ G+++ V + Sbjct: 1509 TPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAANEAGDIQRDFTVVV 1568 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 + P + + + I Q G + G P P Sbjct: 1569 HEPPSVPHAGDVINQTILAGFSTQLECKATGTPLP 1603 Score = 74.9 bits (176), Expect = 2e-11 Identities = 111/560 (19%), Positives = 216/560 (38%), Gaps = 34/560 (6%) Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191 ++RW ++G E+ N ++I L + D+GEY C + G+++ L V Sbjct: 1043 VIRWLRNGQELT-GNEPGVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTERKYQLKV 1101 Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDV-TWYKKKSVIEDTEKFTLISDVKK 1250 P + + + + L ++ V TWYK++ + ++ ++ D+ K Sbjct: 1102 NVPPDFTDNEVSRNVSLVLSQSTSLVCDVTGSPSPVITWYKEEMPVVASDNVQIL-DMGK 1160 Query: 1251 RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTL 1307 TL + K D Y+C ++ A S K V PP I + +++L Sbjct: 1161 -TLRLLKADPADSGSYSCKAVNIAGSAEKGFFVAVLVPPTIKGSGSSHDTVAMVTQEISL 1219 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + P P +W + K + + ++ L IK D Y+ + N G Sbjct: 1220 ECKVEGLPFPTIQWYKDRKQVF-LGDPNLEVTNRGQILRIKSARLGDKARYQCSVMNTAG 1278 Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTG--NSTIIYYVVEYQEIDTT 1425 + N+++ P+ G + + + E E G T+ +Y + Sbjct: 1279 KESRDFNLSVHVPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGR 1338 Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 + T+ ++ L+ ++ R Y + ++E T V I+ Sbjct: 1339 Q----TQYTERGRFLKILRVQATDAGR-YTCKAASVVGSTEKTFELDVYLPPTIKGDDAG 1393 Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXX 1543 + + + + L C GG P P +TW +DG ++ +++ E Sbjct: 1394 PTERKVVLSAS--LILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLS 1451 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y C+A + GE E V + P I I++ + H + E T G Sbjct: 1452 DSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGAGVITHSTVIINHPLEMECQAT----GT 1507 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P V WYK+G ++ + + + + ++ ++ S ++++ A+N AG + T Sbjct: 1508 PTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQI--SDTARFQCVAANEAGDIQRDFT 1565 Query: 1660 LKVYDKPSKPE-GPVIMREI 1678 + V++ PS P G VI + I Sbjct: 1566 VVVHEPPSVPHAGDVINQTI 1585 Score = 72.5 bits (170), Expect = 1e-10 Identities = 81/323 (25%), Positives = 124/323 (38%), Gaps = 22/323 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P ++ P V E + L C L+A P P WL + D+ + V + +H Sbjct: 690 PVIARSPSVLSVVEDQPVTLPCVLLAGNPLPARQWLHNYGLVTTDQYVKVRKDGSLH--- 746 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE--KEPPQVIEPLKSMIVRQGE 750 I V+ G YT +A N G + L + + PQV + +G Sbjct: 747 ----IERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVIPTIQHGPQVFNTI------EGT 796 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 V L + +G P P ITW K K + D+ + + G + A N+ Sbjct: 797 PVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDSDGSLFINSPSGNESGEFICMATNA 856 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A +TV NAE P ++V E L V P P+ITW + Sbjct: 857 AGHASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTEGEDAILPCEVHSVPPPTITWAKER 916 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 +ISP +++++ + V DSG Y CVASN AG + V + V Sbjct: 917 -LISPFAPRHHPLPSCSMKILESKVS---DSGIYVCVASNIAGNLT--LSVLLSVLVPPS 970 Query: 931 VKHLQKSYETEEGKTVILECQTS 953 ++ + + + G V L C S Sbjct: 971 IQPGPRVMKVQVGHPVELPCMVS 993 Score = 68.9 bits (161), Expect = 1e-09 Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 20/258 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP S K GS +L C +++ ++ WL G + ++V Sbjct: 376 PPAISVKGNVT-ASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNRS----- 429 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L++++V Q G Y VA+N G S I L T ++EP + P R G+ V Sbjct: 430 --LQLSSVSPDQSGWYECVAMNEGGVTSEQIYL---TVQEEPRVSVHPANQTFSR-GDEV 483 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + G P P + W N+ VKA G + I ++ KD GVY A N G Sbjct: 484 HMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIRNTEQ-KDGGVYRCLASNQAG 542 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 T++V+T E P+ ++ V L + P P I WY+ Sbjct: 543 TDATNSVLTY-------IESPVVTVALGDVLVALGEAAVLACAASGTPQPEIWWYKAAPE 595 Query: 873 ISPSETITQNFDGENIEL 890 + + T + G N+ L Sbjct: 596 FTREPSDTASDIGSNVTL 613 Score = 66.5 bits (155), Expect = 8e-09 Identities = 63/284 (22%), Positives = 105/284 (36%), Gaps = 17/284 (5%) Query: 632 IPPTFSKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 +PPT + V G+ + LEC +P P + W G+ I+ Sbjct: 1290 VPPTIKGGNASTGVTALLGTVVTLECEGRGVPPPTVTWYRNGQAILSGRQTQYTERGRF- 1348 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 LKI V+ G YT A + G L + P + +V Sbjct: 1349 -----LKILRVQATDAGRYTCKAASVVGSTEKTFELDVYLPPTIKGDDAGPTERKVVLSA 1403 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 S+IL + G P P++TW K+ PV+ + + + + D G Y A + Sbjct: 1404 -SLILECEAGGRPPPSLTWLKDGVPVRHSQSLRVLELGGKIEISSATLSDSGRYVCVATS 1462 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 G E +TV P + TV +++ + T P P +TWY++ Sbjct: 1463 VAGEKEVKYDVTVLVPPFIQGAGVI-----THSTVIINHPLEMECQATGTPTPVVTWYKD 1517 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 + I E G+ + + + D+ ++CVA+N AG Sbjct: 1518 GKPIQQGEGWRVAAGGQRLLVSRAQIS---DTARFQCVAANEAG 1558 Score = 64.9 bits (151), Expect = 2e-08 Identities = 79/390 (20%), Positives = 147/390 (37%), Gaps = 33/390 (8%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKL 1360 GS+VTL + +P P W + + T S+ L + D +Y Sbjct: 608 GSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGLHFTHLWVEDEAVYVC 667 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN------TGNSTII- 1413 N+ G + + +T+ P ++ S +++ D+P GN Sbjct: 668 EAHNHFGKIEAKARITVTGLVLP-----VIARSPSVLSVVEDQPVTLPCVLLAGNPLPAR 722 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 ++ Y + T +++ V+ I+ ++ + + A N V + + + T Y + Sbjct: 723 QWLHNYGLVTTDQYVKVRK--DGSLHIERVRLDHVGDYTCLAENVVGLYNHTTTLNVYVI 780 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--EN 1531 PT++ + T + L C GVP P++TW ++GK L + ++ Sbjct: 781 --------PTIQHGPQVFNTIEGTPVTLPCRAIGVPSPEITWTKEGKLLYLGGPDFFLDS 832 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI-----SNEDIKQKHKV 1586 + C+A N G + + +P S E ++ Sbjct: 833 DGSLFINSPSGNESGEFICMATNAAGHASRRVQLTVYVRPRSNAEGPGSSAEPLRMSVTE 892 Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G++ ++ + +PPP + W K +L + S+ +I E K S S Y Sbjct: 893 GEDAILPCEVHSVPPPTITWAKE--RLISPFAPRHHPLPSCSM-KILESKVSDSGIYVCV 949 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 ASN AG ++ V L V PS GP +M+ Sbjct: 950 ASNIAGNLTLSVLLSVLVPPSIQPGPRVMK 979 Score = 63.3 bits (147), Expect = 7e-08 Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 14/206 (6%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 ++ ECQ G P P +TW++ KP Q + + L++ D F CVA Sbjct: 1498 LEMECQATGTPTPVVTWYKDG---KPIQQGEGWRVAAGGQRLLVSRAQISDTARFQCVAA 1554 Query: 587 NAAG-FASSTTELIVEAPLSDHGSEM---TVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 N AG T ++ E P H ++ T+ +PP S + Sbjct: 1555 NEAGDIQRDFTVVVHEPPSVPHAGDVINQTILAGFSTQLECKATGTPLPVPPVISSQGGT 1614 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVK 701 V LEC +P P WL G + + V E L + + Sbjct: 1615 VTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQVLSEG------RALSLNSAL 1668 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKI 727 GTYT VAVN GE L++ Sbjct: 1669 VTDTGTYTCVAVNAGGEQQREYDLRV 1694 Score = 62.9 bits (146), Expect = 9e-08 Identities = 56/243 (23%), Positives = 91/243 (37%), Gaps = 16/243 (6%) Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH 787 K EPP I ++ G +L+ V+ +TW + + + P + D Sbjct: 369 KISSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSFNLTWLRGGRDARLGPQVNVLDNR 428 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 S+ L G Y A N G+ +TV+E EP + ++ + T Sbjct: 429 SLQ-LSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQE------EPRVSVHPANQ-TFSRG 480 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 + + + PVP + W N+ + S DG L I N + + D G Y+C+ Sbjct: 481 DEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDG---MLAIRNTEQK-DGGVYRCL 536 Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKK 965 ASN AG + + +T V V G+ +L C S T + WY Sbjct: 537 ASNQAGTDATNSVLTYIESPVVTV--ALGDVLVALGEAAVLACAASGTPQPEIWWYKAAP 594 Query: 966 EIS 968 E + Sbjct: 595 EFT 597 Score = 57.2 bits (132), Expect = 5e-06 Identities = 48/212 (22%), Positives = 82/212 (38%), Gaps = 11/212 (5%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DG----KKLKTAKATYENRXXX 1535 +P + + ++ ++ L C+ G P P+VTW R DG + +T + ++R Sbjct: 593 APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE--WLVT 1593 Y C A N G++E + + V+ + V D+ L Sbjct: 653 HFTHLWVEDEAVYVCEAHNHFGKIEAKARITVTGL-VLPVIARSPSVLSVVEDQPVTLPC 711 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 ++ G P P W N + D+ + K + I+ ++ H YT A N G Sbjct: 712 VLLAGNPLPARQWLHNYGLVTTDQYVKV---RKDGSLHIERVRLDHVGDYTCLAENVVGL 768 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 + TL VY P+ GP + I VT+ Sbjct: 769 YNHTTTLNVYVIPTIQHGPQVFNTIEGTPVTL 800 Score = 55.6 bits (128), Expect = 1e-05 Identities = 46/217 (21%), Positives = 82/217 (37%), Gaps = 11/217 (5%) Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 RA +V+ I A ++ K+ + + P N+T P LTC Sbjct: 349 RASSVSFSSIKPAGVEGDWEKI---SSSEPPPAISVKGNVTASPGSRAVLTCHVISTVSF 405 Query: 1512 KVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 +TW R G+ +L +NR Y+C+A N+ G + +Q+ Sbjct: 406 NLTWLRGGRDARLGPQVNVLDNR-SLQLSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQE 464 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 +P +++ Q GDE + G P P ++W N ++ + + + Sbjct: 465 EPRVSV--HPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRM---GPDGM 519 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + I+ ++ Y ASN AGT + L + P Sbjct: 520 LAIRNTEQKDGGVYRCLASNQAGTDATNSVLTYIESP 556 Score = 52.8 bits (121), Expect = 1e-04 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 7/180 (3%) Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXX 1534 ++ P PL+ N+ I C G+P+P + W R+G++L + + E+ Sbjct: 1011 EVLEPPFNSPLQERVA--NQRIAFPCPAKGLPKPVIRWLRNGQELTGNEPGVSILEDGTL 1068 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y C A ND G E + + P T + + + Sbjct: 1069 LLLASVSPLDSGEYVCAAANDAGSTERKYQLKVNVPPDFTDNEVSRNVSLVLSQSTSLVC 1128 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P + WYK + I KT +R+ + + S Y+ +A N AG++ Sbjct: 1129 DVTGSPSPVITWYKEEMPVVASDNVQILDMGKT--LRLLKADPADSGSYSCKAVNIAGSA 1186 Score = 50.8 bits (116), Expect = 4e-04 Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 3/130 (2%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXX 1538 + P V N T +++ + C G P P++ W + +K +++ Sbjct: 464 EEPRVSVHPANQTFSRGDEVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGMLAIR 523 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y+C+A N G T+ V+ + PV+T++ D+ +G+ ++ G Sbjct: 524 NTEQKDGGVYRCLASNQAGTDATNSVLTYIESPVVTVALGDVLV--ALGEAAVLACAASG 581 Query: 1599 IPPPEVIWYK 1608 P PE+ WYK Sbjct: 582 TPQPEIWWYK 591 Score = 45.6 bits (103), Expect = 0.015 Identities = 28/138 (20%), Positives = 54/138 (39%), Gaps = 4/138 (2%) Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGS 1303 ++ + R+L + + D Y CV ++ T ++ + V+ P++ + RG Sbjct: 422 VNVLDNRSLQLSSVSPDQSGWYECVAMNEGGVTSEQIYLTVQEEPRVSVHPANQTFSRGD 481 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 +V + +P P W N +K + D L I+ E D G+Y+ Sbjct: 482 EVHMRCSASGYPVPRLVWTHNDMFVKASSRHRMGPDGM---LAIRNTEQKDGGVYRCLAS 538 Query: 1364 NNCGHADVEMNVTILDKP 1381 N G +T ++ P Sbjct: 539 NQAGTDATNSVLTYIESP 556 Score = 44.0 bits (99), Expect = 0.046 Identities = 76/333 (22%), Positives = 123/333 (36%), Gaps = 32/333 (9%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 EK +L V+ PT + P E+ K S + EC+ G P P +TW + Sbjct: 1374 EKTFELDVYLPPTIKGDDAGP--TER---KVVLSASLI-LECEAGGRPPPSLTWLKDGVP 1427 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 ++ SQ ++ + + I D+G + CVA + AG ++ V P G+ Sbjct: 1428 VRHSQSLRVL---ELGGKIEISSATLSDSGRYVCVATSVAGEKEVKYDVTVLVPPFIQGA 1484 Query: 610 EMTVXXXXXXXXXXXXADILEGIPP---TFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 + G P T+ K K EG + + + + I+ Sbjct: 1485 GVITHSTVIINHPLEMECQATGTPTPVVTWYKDGKPIQQGEGWRVAAGGQRLLVSRAQIS 1544 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK 726 + + + +E D+ +V+ V + + +N+ A L+ Sbjct: 1545 DTARFQCVAANE------AGDIQRDFTVV----VHEPPSVPHAGDVINQTILAGFSTQLE 1594 Query: 727 IK-TGEKEP-PQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---- 779 K TG P P VI + V E L + G P P+ TW K+ PV ++P Sbjct: 1595 CKATGTPLPVPPVISSQGGTVTVLVNEPARLECEATGVPSPSFTWLKDGSPVASVPHGLQ 1654 Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 S+G S L V D G YT A N+ G Sbjct: 1655 VLSEGRALS---LNSALVTDTGTYTCVAVNAGG 1684 Score = 39.5 bits (88), Expect = 0.99 Identities = 25/92 (27%), Positives = 37/92 (40%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F + + GS V C V GYP PQ+TW RQ + ++ + L Sbjct: 593 APEFTREPSDTASDIGSNVTLWCLVRGYPDPQVTWRRQDGLPPFNRPRTYGSVTQSRRGL 652 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 ++ ED + C A N G + + V Sbjct: 653 HFTHLWVEDEAVYVCEAHNHFGKIEAKARITV 684 Score = 38.3 bits (85), Expect = 2.3 Identities = 20/77 (25%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 +G+P P + W +NG +L + E ++ E +++ + + S +Y A+N AG++ Sbjct: 1037 KGLPKPVIRWLRNGQELTGN-EPGVSILEDGTLLLLASVSPLDSGEYVCAAANDAGSTER 1095 Query: 1657 EVTLKVYDKPSKPEGPV 1673 + LKV P + V Sbjct: 1096 KYQLKVNVPPDFTDNEV 1112 Score = 36.7 bits (81), Expect = 7.0 Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 4/125 (3%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX-XXXXXXXXXXX 1544 +PL+ TE ED L C VP P +TW ++ A + Sbjct: 884 EPLRMSVTE-GEDAILPCEVHSVPPPTITWAKERLISPFAPRHHPLPSCSMKILESKVSD 942 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C+A N G + S ++ + P I +K + VG + ++ G+P P + Sbjct: 943 SGIYVCVASNIAGNLTLSVLLSVLVPPSIQPGPRVMKVQ--VGHPVELPCMVSGVPEPTL 1000 Query: 1605 IWYKN 1609 W ++ Sbjct: 1001 TWTRD 1005 >UniRef50_UPI0000F1EA79 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 512 Score = 123 bits (296), Expect = 6e-26 Identities = 100/413 (24%), Positives = 163/413 (39%), Gaps = 12/413 (2%) Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADV 1719 K K P V E R V + W P+ + Y IEK + W +V V Sbjct: 68 KAEGKAPGPPSKVCASETDRTYVVLSWVSPVYHSKAPMWYY-IEKLQVGAGSWQRVNTKV 126 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD-VPSXXXXXXXXXX 1778 Y + L+E +Y+FRV++ N G SE E + L VPS Sbjct: 127 PIRSPRYAVFDLSEGKDYLFRVLSANIYGISEPSEPTSTITTLQLKGVPSAPGQVVATRE 186 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835 D SV I W P + +I Y ++ +G K W R + L+ +Y Sbjct: 187 TDT-SVLIQWAPPKDPNN--LIGYYIDSCVKGSKDWASANHKPHKHTRFVVHGLTTGESY 243 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 FR+ A NE+G S +++ L PS P + + S+ L W +P +GG+ Sbjct: 244 VFRVQAINELGLSDESQESAPLSVRAALKLPSSPYDISLLYCDGESMVLNWKQPIHSGGA 303 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TES 1954 +T+Y I+ V K+W ++ H + + FR+ N VGV P T S Sbjct: 304 EVTDYYIDKCNVAKKTWKEVNIPPVKERLHKVGGLTAGSVYQFRVYGANVVGVGDPSTAS 363 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM 2014 S R + P L V + ++ W P ++G + + GY I W Sbjct: 364 PSFRCDAWTMSEPGPAYDLTFTEVRDDSLVVEWKPPVYNGASAVTGYFIEKCKKGSDSWS 423 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARN--EIGLSEPLESDEPFKVIPGE 2065 +V + V+ ++ L +Y+ R+ A N ++G++ + +P + Sbjct: 424 KVNESSVDHCYLKVKGLETGTSYLFRVRAENAKDVGMASTPSDPVCVRALPAQ 476 Score = 45.6 bits (103), Expect = 0.015 Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 19/187 (10%) Query: 1301 RGSDVTLLVDYQAFPQPN-------DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 R +D ++L+ + PN D + SK H KP K + + Sbjct: 185 RETDTSVLIQWAPPKDPNNLIGYYIDSCVKGSKDWASANH-KPH---KHTRFVVHGLTTG 240 Query: 1354 DAGIYKLRLENNCGHAD-----VEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 ++ +++++ N G +D ++V L PS P ++L D S+ + W +P ++ Sbjct: 241 ESYVFRVQAINELGLSDESQESAPLSVRAALKLPSSPYDISLLYCDGESMVLNWKQPIHS 300 Query: 1408 GNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G + + Y ++ + W +++ + + + L S Y+FR Y N V + D S Sbjct: 301 GGAEVTDYYIDKCNVAKKTWKEVNIPPVKERLHKVGGLTAGSVYQFRVYGANVVGVGDPS 360 Query: 1466 ETTEYYK 1472 + ++ Sbjct: 361 TASPSFR 367 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 4/103 (3%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV--KNITKTQT 1438 PS PG+ +S+ I W P++ N +I Y ++ + +W S K T+ Sbjct: 175 PSAPGQVVATRETDTSVLIQWAPPKDPNN--LIGYYIDSCVKGSKDWASANHKPHKHTRF 232 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481 + L T SY FR A+NE+ +SD S+ + V K+ S Sbjct: 233 VVHGLTTGESYVFRVQAINELGLSDESQESAPLSVRAALKLPS 275 Score = 41.5 bits (93), Expect = 0.25 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 2/94 (2%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITK 1435 + +P P E+ S+ + W P G S + Y +E + + W V ++ Sbjct: 373 MSEPGPAYDLTFTEVRDDSLVVEWKPPVYNGASAVTGYFIEKCKKGSDSWSKVNESSVDH 432 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ L+T +SY FR A N D+ AS ++ Sbjct: 433 CYLKVKGLETGTSYLFRVRAENAKDVGMASTPSD 466 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 4/91 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP K E D + + + W P + + YY +E ++ W V I + Sbjct: 74 PGPPSKVCASETDRTYVVLSWVSPVYHSKAPMWYY-IEKLQVGAGSWQRVNTKVPIRSPR 132 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 ++ +L Y FR + N IS+ SE T Sbjct: 133 YAVFDLSEGKDYLFRVLSANIYGISEPSEPT 163 >UniRef50_P0C5E3 Cluster: Palladin; n=24; Amniota|Rep: Palladin - Rattus norvegicus (Rat) Length = 603 Score = 122 bits (294), Expect = 1e-25 Identities = 102/367 (27%), Positives = 159/367 (43%), Gaps = 23/367 (6%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 Q L+ E Y + + + E D++ E P E + AP F KL+ +G V F C Sbjct: 243 QRLISEIEY-RLERSPVEESGDEVQEAEVPV--ENAAAPFFEMKLKHYKIFEGMPVTFTC 299 Query: 532 QVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +V G P+P+I WF+ I P D + + D D +L +D G +T +A N G Sbjct: 300 RVAGSPKPKIYWFKDGKQISPKSDHYTIQRDVDGTCSLHTTASTLDDDGNYTIMAANTQG 359 Query: 591 FASSTTELIVEA-------PLSDHGSEMTVXXXXXXXXXXXXADILEG--IPPTFSKKPK 641 S T L+V+A P S G + ++ P F + P Sbjct: 360 RVSCTGRLMVQAVNQRGRSPRSPPGHPHARRPRSRSRDSGDENEPIQERFFRPHFLQAPG 419 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI-ESDMHMYCSVLKITNV 700 V EG ++C++ +P PD++W G+ I PD + + E+ +H L I V Sbjct: 420 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHS----LIIEPV 475 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVV 759 G YT +A NR G+ S + L + E + P IE L++ V G V L +V Sbjct: 476 TSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNTGVADGYPVRLECRVS 535 Query: 760 GNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G P P I W K N+ + + D + +++ +D G YT+ A+N GI Sbjct: 536 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 595 Query: 816 TSAVITV 822 +A + V Sbjct: 596 CTARLDV 602 Score = 83.8 bits (198), Expect = 5e-14 Identities = 84/330 (25%), Positives = 140/330 (42%), Gaps = 45/330 (13%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F K K + EG + CR+ P+P I W G++I P + I+ D+ CS Sbjct: 278 PFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKIYWFKDGKQISPKSD-HYTIQRDVDGTCS 336 Query: 694 VLKITNVKKFQEGTYT-----------------VVAVNREGE----------ASLPIVLK 726 L T +G YT V AVN+ G A P Sbjct: 337 -LHTTASTLDDDGNYTIMAANTQGRVSCTGRLMVQAVNQRGRSPRSPPGHPHARRPRSRS 395 Query: 727 IKTG-EKEP-------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL 778 +G E EP P ++ + V++G+ + +V G P P ++W + KP++ Sbjct: 396 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPD 455 Query: 779 PTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 + HS+ I++P +D G+YT A N G + S + + +E + P+ Sbjct: 456 SAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAG--QNSFNLELVVAAKEAHKAPV 512 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIELVIT 893 FI + Q V + ++L RV+ P P I W + NE ++ S + ++ + D ++ Sbjct: 513 FIEKLQNTGVADGYPVRLECRVSGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI 572 Query: 894 NVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ D+G Y A N AG S AR+ + Sbjct: 573 QGATKEDAGWYTVSAKNEAGIVSCTARLDV 602 Score = 55.6 bits (128), Expect = 1e-05 Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%) Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 EP +E P F+ ++TV+E ++ +V+ P P ++W + + I P Sbjct: 403 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLV 462 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYE 939 + +I + D+G Y C+A+N AG++S + + ++ F++ LQ + Sbjct: 463 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNT-G 521 Query: 940 TEEGKTVILECQTSHTVSTKWYHNKKEISGMDH 972 +G V LEC+ S + + KKE + H Sbjct: 522 VADGYPVRLECRVSGVPPPQIFW-KKENESLTH 553 Score = 51.2 bits (117), Expect = 3e-04 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 12/185 (6%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXX-XXXXX 1544 ++T + + + C G+P P ++W DGK ++ A EN Sbjct: 420 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLIIEPVTSRD 479 Query: 1545 XXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV--TAVIEGIP 1600 Y CIA N G+ VV ++ + E + Q V D + V + G+P Sbjct: 480 AGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKL-QNTGVADGYPVRLECRVSGVP 538 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVI--RIKELKRSHSSKYTIEASNTAGTSSVEV 1658 PP++ W K L + + ++ I I+ + + YT+ A N AG S Sbjct: 539 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 598 Query: 1659 TLKVY 1663 L VY Sbjct: 599 RLDVY 603 Score = 48.8 bits (111), Expect = 0.002 Identities = 22/47 (46%), Positives = 32/47 (68%) Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 + + TLVI E FPEDAG FTC A+N G +ST +L+V + +++ S Sbjct: 2 EEICTLVIAESFPEDAGIFTCSARNDYGSVTSTAQLVVTSANTENCS 48 Score = 48.0 bits (109), Expect = 0.003 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 + E+ + E ENA P F + + + E + RV +P P I W+++ + Sbjct: 258 VEESGDEVQEAEVPVENAAAPFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKIYWFKDGKQ 317 Query: 873 ISPSE---TITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ISP TI ++ DG ++ + +D D G+Y +A+N+ G+ S R+ + Sbjct: 318 ISPKSDHYTIQRDVDGTCSLHTTASTLD---DDGNYTIMAANTQGRVSCTGRLMV 369 Score = 44.4 bits (100), Expect = 0.035 Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 16/191 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F++ D V+E + ++ +++ T D+ W+ DG+ I+P + + L Sbjct: 412 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPIRPDSAHKMLVRENGVHSLI 471 Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTV----VELPPEIITRLQNQKVNKGNKATFE 1127 I + D G Y+CI + S E+ V P I +LQN V G E Sbjct: 472 IEPVTSRDAGIYTCIATNRAGQNSFNLELVVAAKEAHKAPVFIEKLQNTGVADGYPVRLE 531 Query: 1128 IELT-KGDALVRWFKDGSEIQFS-NHIQLTIDGKKQ-KLKIYDCDLDDAGEYSC----EV 1180 ++ + W K+ + S + + + D L I +DAG Y+ E Sbjct: 532 CRVSGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 591 Query: 1181 GNSKCTAILTV 1191 G CTA L V Sbjct: 592 GIVSCTARLDV 602 Score = 37.5 bits (83), Expect = 4.0 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 Y + + ++ + + +V E +P E LK+ + TC G P+PK+ Sbjct: 251 YRLERSPVEESGDEVQEAEVPVENAA-APFFEMKLKHYKIFEGMPVTFTCRVAGSPKPKI 309 Query: 1514 TWYRDGKKLKTAKATY 1529 W++DGK++ Y Sbjct: 310 YWFKDGKQISPKSDHY 325 >UniRef50_Q92859 Cluster: Neogenin precursor; n=34; Euteleostomi|Rep: Neogenin precursor - Homo sapiens (Human) Length = 1461 Score = 122 bits (294), Expect = 1e-25 Identities = 134/576 (23%), Positives = 226/576 (39%), Gaps = 37/576 (6%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 +D+ L C+ G+P P + W ++ + L T + Y CIA Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N + +E + +Q +P +I + + + + G P P V W KNG+ + Sbjct: 324 NGNETIEAQAELTVQAQPEFLKQPTNIYAHESM--DIVFECEVTGKPTPTVKWVKNGDMV 381 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP- 1672 + I + V+ L +S Y A N G + L + + GP Sbjct: 382 IPSDYFKIVKEHNLQVL---GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPL 438 Query: 1673 ------VIMREISRESVTIEWKPPLDD-GGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 V+ +S + + W+ P D G LT E ++ +++ Sbjct: 439 PSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQV 498 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP-SXXXXXXXXXXIDNESV 1784 IQ L Y+FRV+AQN G E+ S P+ ++T +V S+ Sbjct: 499 -TIQNLMPATVYIFRVMAQNKHGSGES--SAPLRVETQPEVQLPGPAPNLRAYAASPTSI 555 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 +TW + +G I +YK+ ++G + I L T Y FR+ A N+ Sbjct: 556 TVTW-ETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNK 614 Query: 1845 IGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYI 1901 G P S + + +TL+ P + P+N + S+S+ + W P + IT Y Sbjct: 615 HG---PGVSTPDVAV-RTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYK 670 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 I ++ KS V G+ IE + E FR++A G T+ S + Sbjct: 671 IRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFE 730 Query: 1962 ----HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 VP P++ L +R + ++IV+ SW PE + + GY AI + + Sbjct: 731 SDLDETRVPEVPSS-LHVRPLVTSIVV-SWTPPE-NQNIVVRGY--AIGYGIGSPHAQTI 785 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 KVD + I +L + Y+I + A N +G PL Sbjct: 786 KVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPL 821 Score = 86.2 bits (204), Expect = 9e-15 Identities = 208/1008 (20%), Positives = 359/1008 (35%), Gaps = 106/1008 (10%) Query: 1035 ILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNT--SVH---DEGEYS 1088 IL SE + + W++DG + + D + L+I N S H DEG Y Sbjct: 71 ILNCSAYSEPSPKIEWKKDGTFLNLVSD--DRRQLLPDGSLFISNVVHSKHNKPDEGYYQ 128 Query: 1089 CILRDESC------TAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFK 1141 C+ ES TA++ V LP ++ + V GN A E+ VRW + Sbjct: 129 CVATVESLGTIISRTAKLIVAGLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQ 187 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPS 1195 + + + + G L I + D G Y C V + S + + +P Sbjct: 188 NRQPLLLDDRVIKLPSGM---LVISNATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPE 244 Query: 1196 INFTL---RLPEFILVPANTDAYLT-VEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 + L + P ++ D L V T + W K + + DTE + + Sbjct: 245 VISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL-DTESSERLVLLAGG 303 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 +L I TEDD Y C+ + T + + E+ V+ P+ + D+ + Sbjct: 304 SLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECE 363 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 P P +W+ N ++ + K K +L + + +D G Y+ EN+ G+A Sbjct: 364 VTGKPTPTVKWVKNGDMVIPSDYFKIV---KEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420 Query: 1371 VEMNVTILDK--------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 + IL+ PS P + + I + W P + + + Y V Y Sbjct: 421 AGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFY--- 477 Query: 1423 DTTEWISVKNITKT------QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 T E I+ + + T Q +IQNL + Y FR A N+ + E++ +V + Sbjct: 478 -TKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNK---HGSGESSAPLRVETQ 533 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX 1534 ++Q P L+ P T + G Y K + + Sbjct: 534 PEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHS 593 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGE-VETS--CVVGIQQKPVITISN--EDIKQKHKVGDE 1589 ++ +A+N HG V T V + P N +++ + Sbjct: 594 YTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIH 653 Query: 1590 WL--VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 W A G I Y+ ++ + E ++ + + + I+ L R + + A Sbjct: 654 WQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQL--IEGLDRGTEYNFRVAA 711 Query: 1648 SNTAGTS------SVEVTLKVYDKPSKPEGPVIMR-EISRESVTIEWKPPLDDGGLELTK 1700 GT S E D+ PE P + S+ + W PP ++ + + Sbjct: 712 LTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPP-ENQNIVVRG 770 Query: 1701 YAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG----FSEALESE 1756 YAI + + VD Y I+ L+ + Y+ + A N VG E+ + Sbjct: 771 YAI--GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTR 828 Query: 1757 PIVIKTALDV--------------PSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIID- 1801 P + +D+ P + ++++ ITW + I D Sbjct: 829 PHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDS 888 Query: 1802 --YKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 Y V K K+K + L NT Y+F + +S + Sbjct: 889 RYYTVRWKTNIPANTKYKNANATTLSYL-VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHG 947 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT---VKGKSWT 1913 T T P + V E +++ + W +P S IT YII + T + W Sbjct: 948 TTFELVPTSPPKDVTVVSKEGKPKTIIVNW-QPPSEANGKITGYIIYYSTDVNAEIHDWV 1006 Query: 1914 KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 I V G+ H I+ + F+I A N+ G+ +E+ R K Sbjct: 1007 -IEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPK 1053 Score = 81.8 bits (193), Expect = 2e-13 Identities = 102/468 (21%), Positives = 183/468 (39%), Gaps = 28/468 (5%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 +G + ++ V G+P P + W KN L+ + + S + I ++ + Y Sbjct: 262 IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGS-LEISDVTEDDAGTYFC 320 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 A N T + L V +P + P + + ES+ I ++ + K+ Sbjct: 321 IADNGNETIEAQAELTVQAQPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKWV--- 375 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLN--ENCEYMFRVIAQNPVGFSEALESEPIVIK-- 1761 N + +D + V+ + +Q L ++ E ++ IA+N VG ++A ++ I+++ Sbjct: 376 ---KNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQA-GAQLIILEHA 431 Query: 1762 --TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG---KKWKXX 1816 T +PS + + +TW + + Y V +EG ++ + Sbjct: 432 PATTGPLPSAPRDVVASL-VSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENT 490 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 IQ L T Y FR+ A+N+ G+ ++ ++ + P N Sbjct: 491 SHPGEMQVTIQNLMPATVYIFRVMAQNKHGSG-ESSAPLRVETQPEVQLPGPAPNLRAYA 549 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEI 1936 ++ S+T+ W P S G I NY + + KG + V V S H + I +K+ E Sbjct: 550 ASPTSITVTWETPVSGNGE-IQNYKLYYME-KGTDKEQDVDV--SSHSYTINGLKKYTEY 605 Query: 1937 IFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP-EWDGG 1995 FR+ A N G + T +VR +P LE+R S +M W P Sbjct: 606 SFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVR--NSKSIMIHWQPPAPATQN 663 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 + GY I R ++ + V L I L Y R+ A Sbjct: 664 GQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAA 711 Score = 79.0 bits (186), Expect = 1e-12 Identities = 85/306 (27%), Positives = 137/306 (44%), Gaps = 35/306 (11%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 I+ G+P F+ +P+ V G++ +L C + A P + W + ++ D+ + + + S Sbjct: 147 IVAGLP-RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRV-IKLPSG 204 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-----K 742 M L I+N + G Y V V G +++K P+VI L Sbjct: 205 M------LVISNATEGDGGLYRCV-VESGGPPKYSDEVELKV--LPDPEVISDLVFLKQP 255 Query: 743 SMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVK- 798 S +VR G+ V+L G P PTI W KN + AL T+S + L+ V Sbjct: 256 SPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE---ALDTESSERLVLLAGGSLEISDVTE 312 Query: 799 -DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 D G Y A+N E A +TV+ A+P F+ + I E I VT Sbjct: 313 DDAGTYFCIADNGNETIEAQAELTVQ------AQPE-FLKQPTNIYAHESMDIVFECEVT 365 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P++ W +N +++ PS+ + N++ V+ V S D G Y+C+A N G + Sbjct: 366 GKPTPTVKWVKNGDMVIPSDYF-KIVKEHNLQ-VLGLVKS--DEGFYQCIAENDVGNAQA 421 Query: 918 GARVTI 923 GA++ I Sbjct: 422 GAQLII 427 Score = 68.1 bits (159), Expect = 2e-09 Identities = 91/384 (23%), Positives = 157/384 (40%), Gaps = 40/384 (10%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-----SDGDTHSITI 791 ++EP+ ++ VR G SVIL+ P P I W K+ + + DG + Sbjct: 56 LVEPVDTLSVR-GSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114 Query: 792 LKPKKVK-DEGVYTLKA--ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + K K DEG Y A E+ I +A + V A P F ++ + +V Sbjct: 115 VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIV-------AGLPRFTSQPEPSSVYAGN 167 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 L V + VP + W +N + + + + + G LVI+N +E D G Y+CV Sbjct: 168 NAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSG---MLVISNA-TEGDGGLYRCVV 223 Query: 909 SNSAGKSSHGARVTI----DVEKVTFVKHLQKSYETEE--GKTVILECQTS--HTVSTKW 960 S G + V + D E ++ + L++ G+ V+L C S T + KW Sbjct: 224 -ESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKW 282 Query: 961 YHNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--- 1016 N++ + + R ++ G D G CI + + + T+ Sbjct: 283 MKNEEALDTESSERLVLLAG--GSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 PEF+++ + E + E E+ + T V W ++G+++ P D+ K L Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPS----DYFKIVKEHNLQ 396 Query: 1076 IRNTSVHDEGEYSCILRDESCTAE 1099 + DEG Y CI ++ A+ Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQ 420 Score = 65.7 bits (153), Expect = 1e-08 Identities = 52/197 (26%), Positives = 87/197 (44%), Gaps = 10/197 (5%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F K+P G D++L C +P P I W+ K EE + E+ E + + L Sbjct: 251 FLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWM-KNEEALDTESS----ERLVLLAGGSL 305 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +I++V + GTY +A N G ++ ++ T + +P + +P ++ + ++ Sbjct: 306 EISDVTEDDAGTYFCIADN--GNETIEAQAEL-TVQAQPEFLKQPT-NIYAHESMDIVFE 361 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 +V G P PT+ W KN V H++ +L K DEG Y AEN G A+ Sbjct: 362 CEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVK-SDEGFYQCIAENDVGNAQ 420 Query: 816 TSAVITVEEPTEENAEP 832 A + + E P Sbjct: 421 AGAQLIILEHAPATTGP 437 Score = 64.1 bits (149), Expect = 4e-08 Identities = 87/402 (21%), Positives = 151/402 (37%), Gaps = 24/402 (5%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVA 683 A I P F +P GS ++L C + P P I W G +V D+ + Sbjct: 45 ASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLL 104 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 D ++ S + + K EG Y VA + K+ P+ + Sbjct: 105 --PDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL--PRFTSQPEP 160 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 V G + IL+ +V + P + W +N +P+ L + + ++ D G+Y Sbjct: 161 SSVYAGNNAILNCEVNADLVPFVRWEQNRQPL-LLDDRVIKLPSGMLVISNATEGDGGLY 219 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 E+ + V P E +F+ + + + L + P P+ Sbjct: 220 RCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPT 279 Query: 864 ITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 I W +N E + SE + G L I++V +E D+G Y C+A N A + Sbjct: 280 IKWMKNEEALDTESSERLVLLAGG---SLEISDV-TEDDAGTYFCIADNGNETIEAQAEL 335 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979 T+ + F+K Y E ++ EC+ + T + KW N + D+ +I++E Sbjct: 336 TVQAQP-EFLKQPTNIY-AHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKE- 392 Query: 980 RXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKETIP 1017 D G +CI V + + L++ E P Sbjct: 393 --HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAP 432 Score = 46.8 bits (106), Expect = 0.007 Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 4/91 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ + + + FEC+V G P P + W + ++ PS F++ + + L Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN----LQ 396 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + D G + C+A+N G A + +LI+ Sbjct: 397 VLGLVKSDEGFYQCIAENDVGNAQAGAQLII 427 Score = 40.3 bits (90), Expect = 0.57 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVI 570 +F+++ P G V C G P P I W + + ++ +L I Sbjct: 250 VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGG--SLEI 307 Query: 571 REVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 +V +DAGT+ C+A N + EL V+A Sbjct: 308 SDVTEDDAGTYFCIADNGNETIEAQAELTVQA 339 >UniRef50_UPI00015A60B9 Cluster: UPI00015A60B9 related cluster; n=3; Danio rerio|Rep: UPI00015A60B9 UniRef100 entry - Danio rerio Length = 3050 Score = 121 bits (291), Expect = 3e-25 Identities = 154/716 (21%), Positives = 267/716 (37%), Gaps = 76/716 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+ + D V E + V + + ++ W RD IK E ++ Sbjct: 671 PAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMI 730 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE----IITRLQNQKVNKGNKATFE 1127 I++ D G Y+C + +E C ++ V P E II +++ V G A FE Sbjct: 731 IKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVRDVMVKAGETALFE 790 Query: 1128 IELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC------- 1178 + D V W DG IQ + + ++ DGK+ +L + DD+G Y+C Sbjct: 791 CHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKE 850 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIED 1238 E+ +S ++ EP FT +L ++ + V W +E+ Sbjct: 851 ELTSSAKLKVIASIEPL--FTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEE 908 Query: 1239 TEKFTLISDVKKRTLII---------------RKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 E ++ + + +LII R +D+C + + + ++ Sbjct: 909 NEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAK 968 Query: 1284 VEFPPKIVDYER--EYRIKR-----------------GSDVTLLVDYQAFPQPNDEWIVN 1324 +E P I + E I+R G + L P P W N Sbjct: 969 LEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHN 1028 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-KPSP 1383 K I + K + SL ++ V + G+YK + N G A ++ + D P P Sbjct: 1029 GKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDP 1088 Query: 1384 P-GKPNILEIDSSSINICWDEPENTGNS---TIIYYVVEYQEIDTTEWISVKNITKTQT- 1438 P G P + I +I + W +P+ S + + Y ++ Q + + +W + + K T Sbjct: 1089 PDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTY 1148 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPN 1496 +I NL Y FR ++ S S TE +++ ++P + + Sbjct: 1149 TISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEK 1208 Query: 1497 EDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE------NRXXXXXXXXXXXXXXXYK 1549 + + +T V VTW R G L +E ++ Sbjct: 1209 QPLSITVTLNHV-NASVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSSDVGQLT 1267 Query: 1550 CIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 CIA N +G SCV+ ++ P ED+ VG+ V+EG P P+++WY Sbjct: 1268 CIANNKYGS--DSCVLTLEMAVAPTFETIMEDLDVN--VGETPRFAVVVEGKPVPDILWY 1323 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 K L + + + + + S YT A N AG+ S + L V+ Sbjct: 1324 KGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVH 1379 Score = 109 bits (263), Expect = 6e-22 Identities = 102/452 (22%), Positives = 183/452 (40%), Gaps = 29/452 (6%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E+ AP+F L+ G+ V +C + G P P++ W + +K S + + + Sbjct: 527 EDPLEAPVFEFPLQDTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGE 586 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE--APLSDHGSEMTVXXXXXXXX 621 +L+I+ P DAGT+T A N G SS+ L ++ A S + S +T Sbjct: 587 R-HSLLIKWTKPSDAGTYTVTAVNEVGEVSSSATLFIKPGACKSKYSSPITSDEEYLSPL 645 Query: 622 XXXX-------------ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL 668 D PP F Q V EG ++ + + P+P + WL Sbjct: 646 EESMDFSSYRGPEPRKIVDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWL 705 Query: 669 FKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 + + + E++ + ++K + ++ G YT +N G L++K Sbjct: 706 -RDRVTIKTGTRHIVQETEEGNFEMIIK--SAQRSDTGVYTCKIINEYGTKQCEGKLEVK 762 Query: 729 TGEKEPP-QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTKSDGD 785 EP +I P++ ++V+ GE+ + V+G + W + K ++ L K D Sbjct: 763 ARPVEPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFD 822 Query: 786 THSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 +L +D+ G YT K ++ +SA + V E PLF + + V Sbjct: 823 GKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIE-----PLFTRKLDVLEV 877 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 E + +V+ P P + W + + +E I +G L+I++V +E D G Y Sbjct: 878 IEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNE-DEGLY 936 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 A NS G+ A + + + + K Sbjct: 937 TVAARNSHGEDECAAELYVQEPRPAISSQIAK 968 Score = 91.9 bits (218), Expect = 2e-16 Identities = 109/475 (22%), Positives = 178/475 (37%), Gaps = 67/475 (14%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 + + Y L++ ++ + P K P F+ + + +G V V Sbjct: 635 ITSDEEYLSPLEESMDFSSYRGPEPRKIVDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLV 694 Query: 534 EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFAS 593 G P+P + W R IK + ++ ++I+ D G +TC N G Sbjct: 695 TGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVYTCKIINEYGTKQ 754 Query: 594 STTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILL 653 +L V+A + G L I P KA G L Sbjct: 755 CEGKLEVKARPVEPG--------------------LAIIRPVRDVMVKA-----GETALF 789 Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVKKFQEGTYTV 710 EC ++ + D+ WL G+ I P + MH C +L + +V + GTYT Sbjct: 790 ECHVIGPQDTDVDWLSDGKLIQP-----ALLNCKMHFDGKRCRLL-LNSVHEDDSGTYTC 843 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 + E L K+K P L + V +G + +V G P P + W Sbjct: 844 KLSTAKEE--LTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSH 901 Query: 771 NNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP-- 825 ++P++ + +G HS+ I+ +DEG+YT+ A NS G E +A + V+EP Sbjct: 902 FDRPLEENEDIRILKEGGRHSL-IISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRP 960 Query: 826 ---------------TEENAEP---------PLFINRFQEITVKEKGTIKLVARVTRNPV 861 EE P P F+ ++ V E L +V P Sbjct: 961 AISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPY 1020 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P+ITW+ N + I +E + ++ ++ G YKCV SN GK++ Sbjct: 1021 PTITWFHNGKRIDSTED-RKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKVGKAT 1074 Score = 87.4 bits (207), Expect = 4e-15 Identities = 112/529 (21%), Positives = 202/529 (38%), Gaps = 32/529 (6%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S+ P+F KL +G +F+C+V G P PQ+ W ++ ++D ++ + Sbjct: 863 SIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGR-H 921 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623 +L+I V ED G +T A+N+ G EL V+ P +S +++ Sbjct: 922 SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEV 981 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +I P F K V EG + +L C++ +P P I W G+ I E+ + Sbjct: 982 PENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMT 1041 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 D+H L + V G Y V N+ G+A+ L + +PP ++S Sbjct: 1042 QFRDVHS----LVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDPPDGAPVVES 1097 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK----D 799 + G+++ LS + P+I ++ S T + LK Sbjct: 1098 I---TGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLS 1154 Query: 800 EGV---YTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGTIKLV 853 +GV + + + S+ ++ S + + E P+ I++ + + EK + + Sbjct: 1155 KGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEKQPLSIT 1214 Query: 854 ARVTRNPV-PSITWYRNNEII---SPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 VT N V S+TW R + P D + L + V S D G C+A+ Sbjct: 1215 --VTLNHVNASVTWKRIGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSS-DVGQLTCIAN 1271 Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEI 967 N G S +T+++ + + + + G+T + + WY + Sbjct: 1272 NKYGSDS--CVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLL 1329 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016 S H + + D GV C K+ S + T+ Sbjct: 1330 SESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1378 Score = 81.0 bits (191), Expect = 3e-13 Identities = 71/312 (22%), Positives = 123/312 (39%), Gaps = 15/312 (4%) Query: 727 IKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786 + T KEPP + + V +G+ V +S V G P+P + W ++ +K +T Sbjct: 663 VDTRFKEPPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQET 722 Query: 787 HS---ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINR-FQEI 842 I+K + D GVYT K N G + + V+ EP L I R +++ Sbjct: 723 EEGNFEMIIKSAQRSDTGVYTCKIINEYGTKQCEGKLEVK---ARPVEPGLAIIRPVRDV 779 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDS 901 VK T V + W + ++I P+ +FDG+ L++ +V E DS Sbjct: 780 MVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSV-HEDDS 838 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-- 959 G Y C S + + + A++ + E EG+ +C+ S T + Sbjct: 839 GTYTCKLSTAKEELTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVI 898 Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTMLVVKET 1015 W H + + + I++EG D G+ + + E + L V+E Sbjct: 899 WSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP 958 Query: 1016 IPEFIRKLQDFE 1027 P ++ E Sbjct: 959 RPAISSQIAKLE 970 Score = 71.7 bits (168), Expect = 2e-10 Identities = 41/169 (24%), Positives = 83/169 (49%), Gaps = 5/169 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G+P P + W+ NG ++++ ++ +T + ++ + +H Y Sbjct: 1006 GREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCV 1065 Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702 SN G ++ L V D P P+G ++ I+ +++T+ WK P D ++ + YA Sbjct: 1066 ISNKVGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYA 1125 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 I++ + +W +A + TY I L++ Y FRV++ FS+ Sbjct: 1126 IQQQALGSIQWTIIASCLKQT-TYTISNLSKGVRYAFRVLSITSKAFSK 1173 Score = 68.1 bits (159), Expect = 2e-09 Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 1/101 (0%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E ++AP F + G T +F VEG P P I W++ ++ S F Y DDN Sbjct: 1284 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVY-DDN 1342 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 +LV+ +D+G +TC AKN AG S EL V ++ Sbjct: 1343 ECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTVHTNIT 1383 Score = 63.7 bits (148), Expect = 5e-08 Identities = 76/320 (23%), Positives = 131/320 (40%), Gaps = 24/320 (7%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF-SNHI-QLTIDGKKQK 1162 PP + + +Q V +G + T + +T + ++ W +D I+ + HI Q T +G + Sbjct: 670 PPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEM 729 Query: 1163 LKIYDCDLDDAGEYSCEV----GNSKCTAILTVE----EPSINFTLRLPEFILVPANTDA 1214 + I D G Y+C++ G +C L V+ EP + +R ++V A A Sbjct: 730 I-IKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAI-IRPVRDVMVKAGETA 787 Query: 1215 YLTVEI--PDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 + P +T DV W +I+ + D K+ L++ EDD YTC L Sbjct: 788 LFECHVIGPQDT-DVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLS 846 Query: 1272 DAK----STTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 AK S+ KLKV + P + G + P P W + Sbjct: 847 TAKEELTSSAKLKV-IASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRP 905 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 +++ + + + SL I V N D G+Y + N+ G + + + +P P Sbjct: 906 LEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYV-QEPRPAISS 964 Query: 1388 NILEIDS-SSINICWDEPEN 1406 I +++ SI + PEN Sbjct: 965 QIAKLEKMPSIPEEPEVPEN 984 Score = 58.0 bits (134), Expect = 3e-06 Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 8/215 (3%) Query: 1284 VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKS 1342 ++FPP R++ + G VTL P P+ W+ + K ++ + S Sbjct: 2371 IDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGR 2430 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L I K DAG+Y+ N V++ P+ PG P + + ++ + W Sbjct: 2431 QLLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVVWR 2490 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 + T T Y +E + W+ V + ++ +L +SYRFR VN+ Sbjct: 2491 PSDTTAPCT---YSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQ 2547 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 S +E V+ ++ ++ P KP + + P+ Sbjct: 2548 GPYSSLSEV--VVLDSTVK-PAAIKPAPSTNSAPS 2579 Score = 56.0 bits (129), Expect = 1e-05 Identities = 40/121 (33%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Query: 491 KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 K++K+P E P +E E+ P FV+ L +G C+V G P P ITWF Sbjct: 968 KLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFH 1027 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 I ++D +M D V +LV+R V G + CV N G A+ + L V L Sbjct: 1028 NGKRIDSTEDRKMTQFRD-VHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILP 1086 Query: 606 D 606 D Sbjct: 1087 D 1087 Score = 53.2 bits (122), Expect = 8e-05 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 6/163 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTI 1645 GD ++ + G P P + W K+ LE D N I+ + ++ I + + + Y Sbjct: 2389 GDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYEC 2448 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 A+N T + + + P+ P P + ++ ++ + W+P D T Y++E+ Sbjct: 2449 VAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVV-WRP--SDTTAPCT-YSLER 2504 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 N W+ VA D Y + L Y FRV N G Sbjct: 2505 KTEGENNWLIVATGVADC-YYNVLDLPAGASYRFRVACVNKAG 2546 Score = 48.8 bits (111), Expect = 0.002 Identities = 25/74 (33%), Positives = 38/74 (51%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E L+ +I G P PEVIW K+ +++N + + + + + IK K S + YT+ Sbjct: 547 GTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSDAGTYTVT 606 Query: 1647 ASNTAGTSSVEVTL 1660 A N G S TL Sbjct: 607 AVNEVGEVSSSATL 620 Score = 48.4 bits (110), Expect = 0.002 Identities = 65/320 (20%), Positives = 119/320 (37%), Gaps = 28/320 (8%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK-CKHTKPSIDSKSASL 1345 PP + + + G +VT+ V P+P W+ + IK +H + + + Sbjct: 670 PPAFLAVIGDQSVIEGQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEM 729 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 IK + +D G+Y ++ N G E + + +P PG I + D Sbjct: 730 IIKSAQRSDTGVYTCKIINEYGTKQCEGKLEVKARPVEPGLAIIRPVR--------DVMV 781 Query: 1406 NTGNSTII-YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 G + + +V+ Q+ D +W+S + Q ++ N K + + +N V D+ Sbjct: 782 KAGETALFECHVIGPQDTD-VDWLSDGKL--IQPALLNCKMHFDGKRCRLLLNSVHEDDS 838 Query: 1465 SETTEYYKVIKETKIQSPTVE-----KPLKNITTEPNEDIE-----LTCIFGGVPQPKVT 1514 T KE S ++ +PL + E IE C G P P+V Sbjct: 839 GTYTCKLSTAKEELTSSAKLKVIASIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVI 898 Query: 1515 WYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ- 1569 W + L+ + R Y A N HGE E + + +Q+ Sbjct: 899 WSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEP 958 Query: 1570 KPVITISNEDIKQKHKVGDE 1589 +P I+ +++ + +E Sbjct: 959 RPAISSQIAKLEKMPSIPEE 978 Score = 48.0 bits (109), Expect = 0.003 Identities = 26/95 (27%), Positives = 41/95 (43%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 P +++ P+F KLR +G V C G P P I+W + ++ M Sbjct: 2366 PFNQKIDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMIS 2425 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 D L+I + +DAG + CVA N +S+ Sbjct: 2426 CPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSS 2460 Score = 47.6 bits (108), Expect = 0.004 Identities = 47/203 (23%), Positives = 75/203 (36%), Gaps = 10/203 (4%) Query: 1375 VTILDKP--SPPGKPNILEIDSSS--INICWDEPENTGNSTIIYYVVEYQEIDT-TEWIS 1429 V I D P +PP P + SS + + P TI +VE + ++T T Sbjct: 422 VAIQDFPVQAPPKPPRVSSSSSSEEKMELEVTPPPPPLKLTIPKIIVEEEPMETDTPVEK 481 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 + K T S R R +++ S Y E +++P E PL+ Sbjct: 482 TEKAVKVGTGKDEKHQRSRGRGRRQRPMSPELATESSDDSYVSA-GEDPLEAPVFEFPLQ 540 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXX 1545 + ++ L CI G P P+V W +D ++K + R Sbjct: 541 DTVASTGTEVLLKCIISGTPLPEVIWKKDNTEVKNSPTHVVKIEGERHSLLIKWTKPSDA 600 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQ 1568 Y A N+ GEV +S + I+ Sbjct: 601 GTYTVTAVNEVGEVSSSATLFIK 623 Score = 45.6 bits (103), Expect = 0.015 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 PP L+ ++ +G+ V LS G+P P I+W K+ KP++ P S D + Sbjct: 2374 PPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLL 2433 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ KD G+Y A N +S V+++ Sbjct: 2434 MIMKTTKKDAGLYECVAANPLATVTSSCVVSL 2465 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 9/118 (7%) Query: 993 DVGVIKCIVKDQ--ETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETA-DVV 1048 DVG + CI ++ S +L ++ + P F ++D +V + V + + D++ Sbjct: 1262 DVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDIL 1321 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102 W + G+ + + + + F + L + NT D G Y+C ++ SC AE+TV Sbjct: 1322 WYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1378 Score = 40.7 bits (91), Expect = 0.43 Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 8/136 (5%) Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTV-EKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 V++ DI AS E + KI P V L++ + + L+C+ G P P ++ Sbjct: 2349 VSQPDIP-ASIARENGSLPFNQKIDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHIS 2407 Query: 1515 WYRDGKKLK-----TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 W +D K L+ + + R Y+C+A N V +SCVV + + Sbjct: 2408 WMKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLAR 2467 Query: 1570 KPVITISNEDIKQKHK 1585 P + ++ QK+K Sbjct: 2468 LP-NSPGTPEVPQKYK 2482 Score = 40.3 bits (90), Expect = 0.57 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT-TKEKTSVIRIKELKRSHSSKYTI 1645 G E ++ ++ G P P + W ++ ++ + + T+E + IK +RS + YT Sbjct: 685 GQEVTMSVLVTGQPKPMLYWLRDRVTIKTGTRHIVQETEEGNFEMIIKSAQRSDTGVYTC 744 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 + N GT E L+V +P +P G I+R + Sbjct: 745 KIINEYGTKQCEGKLEVKARPVEP-GLAIIRPV 776 Score = 39.1 bits (87), Expect = 1.3 Identities = 38/186 (20%), Positives = 68/186 (36%), Gaps = 9/186 (4%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYEN-RXXXXXXXX 1540 +P++++ + E C G V W DGK ++ A K ++ R Sbjct: 774 RPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLNSV 833 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGI--QQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C E+ +S + + +P+ T D+ + + G + G Sbjct: 834 HEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPLFT-RKLDVLEVIE-GRNARFDCKVSG 891 Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 PPP+VIW LE +++ I + + I + YT+ A N+ G Sbjct: 892 TPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDECAA 951 Query: 1659 TLKVYD 1664 L V + Sbjct: 952 ELYVQE 957 >UniRef50_Q17AE8 Cluster: Titin; n=3; Culicidae|Rep: Titin - Aedes aegypti (Yellowfever mosquito) Length = 1393 Score = 120 bits (290), Expect = 3e-25 Identities = 116/433 (26%), Positives = 184/433 (42%), Gaps = 57/433 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ E +V G P P++ W +++F +Y++ A LVI E F +DAG +T Sbjct: 21 GQKIKLEAEVAGTPPPEVMWSHDGMHFS-NREF--FYENGR-AQLVIDEAFLKDAGVYTL 76 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 AKN AG S + ++V+ L + S+ + A +E + P+ + K Sbjct: 77 TAKNIAGEKSCSCNVVVKGRLPNETSDSEL------------ASDMEPVKPSVQLQLKDV 124 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V EG + L+C +V PEP++ W + + + + D +CS L I Sbjct: 125 SVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGD---HCS-LVIREAFLE 180 Query: 704 QEGTYTVVAVNREGEASLP---IVLKIKTGE---KEPPQVIEP-----------LKSMIV 746 G Y VVA+N GEAS IV + E ++P + I P L ++ Sbjct: 181 DAGEYRVVAINSAGEASSKCSVIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDILA 240 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPT-----KSDGDTHSITILKPKKVKDEG 801 +GE V G+PRP I W NN+ + P + DG I++ D+G Sbjct: 241 AEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHSVYRDDGVVK--LIIEQVFPDDKG 298 Query: 802 VYTLKAENSEGIAE--TSAVITVEEPTEENAEP---------PLFINRFQEITVKEKGTI 850 VYT KA N G A+ ++ ++ E + P P F F + VK + Sbjct: 299 VYTAKAFNPSGEAKCFSNLIVKSINAAEFESVPAFLSDSVVCPTFKELFADRVVKLHEST 358 Query: 851 KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 K V P P I W+ N++ + + + G+ L I V E+ +G C A N Sbjct: 359 KFECIVVGKPQPKIKWFFNDQPVQGHDFLVST-SGDRQVLTIPEVSPEL-AGKITCFAEN 416 Query: 911 SAGKSSHGARVTI 923 AG + A V + Sbjct: 417 EAGNAQCVAYVRL 429 Score = 112 bits (270), Expect = 9e-23 Identities = 100/338 (29%), Positives = 143/338 (42%), Gaps = 30/338 (8%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+ + + P +L+ +G V+ +C + G P P++ W+ +K S DFQ+ + Sbjct: 108 SDMEPVKPSVQLQLKDVSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQG 167 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 D+ +LVIRE F EDAG + VA N+AG ASS +IV PL+ +E V Sbjct: 168 DH-CSLVIREAFLEDAGEYRVVAINSAGEASSKCSVIV-TPLNI--AEPAVRQPAERILP 223 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 G PP F + EG EC + P P+I W EIV + + Sbjct: 224 AL------GAPPKFERLLSDILAAEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHS 277 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA---SLPIVLKIKTGEKEP----- 734 D + L I V +G YT A N GEA S IV I E E Sbjct: 278 VYRDDGVV---KLIIEQVFPDDKGVYTAKAFNPSGEAKCFSNLIVKSINAAEFESVPAFL 334 Query: 735 ------PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDT 786 P E +V+ ES VVG P+P I W N++PV+ + GD Sbjct: 335 SDSVVCPTFKELFADRVVKLHESTKFECIVVGKPQPKIKWFFNDQPVQGHDFLVSTSGDR 394 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +TI + + G T AEN G A+ A + + + Sbjct: 395 QVLTIPEVSP-ELAGKITCFAENEAGNAQCVAYVRLAD 431 Score = 81.0 bits (191), Expect = 3e-13 Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 11/205 (5%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + VD+G+D+ E + P P++ E+ PD +A+ ++ Sbjct: 568 PRFVSPFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGE-RIAVSYSLNKI-- 624 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 V+++ NV G YT A N G +S L +K PP L++ V +GE +I Sbjct: 625 VVELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIF-PPVFGRRLQAQSVHRGERII 683 Query: 754 LSAQVVGNPRPTITWCKNNKPVK------ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 L A+V G P PT+ W K+N+PV+ + + G T + I + D G + + A Sbjct: 684 LDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKL-IFEQIDFADAGKFMIVA 742 Query: 808 ENSEGIAETSAVITVEEPTEENAEP 832 N+ G A++ A I V E + +P Sbjct: 743 RNTGGEAQSIADIAVMEAEQPQPQP 767 Score = 74.5 bits (175), Expect = 3e-11 Identities = 82/314 (26%), Positives = 125/314 (39%), Gaps = 41/314 (13%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+F P G I LE + P P++ W G N E+ + Sbjct: 7 PSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHF---SNREFFYENGR----A 59 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK------TGEKEPPQVIEP------- 740 L I G YT+ A N GE S + +K T + E +EP Sbjct: 60 QLVIDEAFLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQL 119 Query: 741 -LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796 LK + V +G+ V L +VG P P + W ++PVK GD H +++ Sbjct: 120 QLKDVSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGD-HCSLVIREAF 178 Query: 797 VKDEGVYTLKAENSEGIAET--SAVIT--------VEEPTEE----NAEPPLFINRFQEI 842 ++D G Y + A NS G A + S ++T V +P E PP F +I Sbjct: 179 LEDAGEYRVVAINSAGEASSKCSVIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDI 238 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDS 901 E + V+ +P P+I W+ NN EI+ + D ++L+I V + D Sbjct: 239 LAAEGEKCQFECAVSGDPRPNIKWFVNNREIVENPRVHSVYRDDGVVKLIIEQVFPD-DK 297 Query: 902 GDYKCVASNSAGKS 915 G Y A N +G++ Sbjct: 298 GVYTAKAFNPSGEA 311 Score = 73.7 bits (173), Expect = 5e-11 Identities = 54/202 (26%), Positives = 90/202 (44%), Gaps = 13/202 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 E P P +++ R G+ + L A+V G P P + W + + + ++ Sbjct: 5 EYPSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHFSNREFFYENGRAQL-VI 63 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEE--PTE-------ENAEP--PLFINRFQE 841 +KD GVYTL A+N G S + V+ P E + EP P + ++ Sbjct: 64 DEAFLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKD 123 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 ++V E ++L + P P + WY + + S F G++ LVI E D+ Sbjct: 124 VSVFEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLE-DA 182 Query: 902 GDYKCVASNSAGKSSHGARVTI 923 G+Y+ VA NSAG++S V + Sbjct: 183 GEYRVVAINSAGEASSKCSVIV 204 Score = 70.9 bits (166), Expect = 4e-10 Identities = 62/234 (26%), Positives = 100/234 (42%), Gaps = 20/234 (8%) Query: 704 QEGTYTVVAVNREGEASLPIVL---KIKTGE----KEPPQVIEPLKSMIVRQGESVILSA 756 QE + +A N E I+ +I TG+ P+ + P IV QG V Sbjct: 530 QETSILNIANNNASELHETIIANSGQISTGKPARRSSAPRFVSPFNGKIVDQGADVAFEG 589 Query: 757 QVVGNPRPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 + G P P + KN+ +P S + LK D G YT A N+ G Sbjct: 590 IIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGA 649 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN--- 870 + T+A + V++ + PP+F R Q +V I L A V+ P P++ W+++N Sbjct: 650 SSTTADLVVKK----SIFPPVFGRRLQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPV 705 Query: 871 -EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 E + P Q G +L+ +D D+G + VA N+ G++ A + + Sbjct: 706 QEALRPGSYTLQQV-GPTCKLIFEQIDF-ADAGKFMIVARNTGGEAQSIADIAV 757 Score = 60.1 bits (139), Expect = 7e-07 Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 11/207 (5%) Query: 399 VTIKKRLNPFEIFYTPVE-VRCGDTVFAVYSYVAETDEAINLVEGERLYILDTSNQDWWY 457 VT++K++ Y+ V G + V+S A D + V G+ I +T + Sbjct: 460 VTLQKQVTTSSSSYSSSTLVENGVSQSEVHSKSAHLDRSFKQVGGQAPEIAETKQ----F 515 Query: 458 VQKHLTEEKGWVPAQ---YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVE 514 Q HL + + Q L NN L + + ++ KP +S AP FV Sbjct: 516 AQFHLANNQPPMIQQETSILNIANNNASELHETIIANSGQIST-GKPA--RRSSAPRFVS 572 Query: 515 KLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF 574 K G+ V FE ++GYP P++ + ++P + N + ++ V Sbjct: 573 PFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVS 632 Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVE 601 DAG +T A NAAG +S+T +L+V+ Sbjct: 633 TNDAGRYTATASNAAGASSTTADLVVK 659 Score = 54.8 bits (126), Expect = 2e-05 Identities = 48/198 (24%), Positives = 75/198 (37%), Gaps = 17/198 (8%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXX 1540 P+ P N+ + I+L G P P+V W DG + YEN R Sbjct: 7 PSFPVPPSNVMARVGQKIKLEAEVAGTPPPEVMWSHDGMHFSNREFFYENGRAQLVIDEA 66 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQK-PVITISNEDIKQKHKV------------- 1586 Y A N GE SC V ++ + P T +E V Sbjct: 67 FLKDAGVYTLTAKNIAGEKSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKDVSV 126 Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G + VI G P PEVIWY ++ ++ + + + I+E + +Y Sbjct: 127 FEGKPVRLDCVIVGQPEPEVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLEDAGEYR 186 Query: 1645 IEASNTAGTSSVEVTLKV 1662 + A N+AG +S + ++ V Sbjct: 187 VVAINSAGEASSKCSVIV 204 Score = 44.4 bits (100), Expect = 0.035 Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 4/90 (4%) Query: 1595 VIEGIPPPEVIWYKNGNKLENDKE-YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 +I+G P PEV KN +L+ D E ++ V+ +K + + + +YT ASN AG Sbjct: 590 IIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGA 649 Query: 1654 SSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 SS L V K P PV R + +SV Sbjct: 650 SSTTADL-VVKKSIFP--PVFGRRLQAQSV 676 Score = 43.6 bits (98), Expect = 0.061 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 2/93 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVAT 567 P+F +L+ + G + + +V G P P + WF+ ++ + Y Sbjct: 665 PVFGRRLQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCK 724 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L+ ++ DAG F VA+N G A S ++ V Sbjct: 725 LIFEQIDFADAGKFMIVARNTGGEAQSIADIAV 757 Score = 43.2 bits (97), Expect = 0.081 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD--DNVAT 567 P+FV L+ G +FEC V P + W + I S Q YY + + + Sbjct: 1289 PLFVAPLKDIAVVSGQPARFECIVACDATPAVRWTKNNVPIDESG--QRYYPEYRNGLCR 1346 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L + + DAG + C+A+N G + + +L V Sbjct: 1347 LSLPVAYEGDAGKYCCLAENHLGHSQTCADLTV 1379 Score = 41.9 bits (94), Expect = 0.19 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 10/118 (8%) Query: 1076 IRNTSVHDEGEYSCILRD----ESCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIE 1129 ++N S +D G Y+ + S TA++ V + PP RLQ Q V++G + + E Sbjct: 628 LKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRRLQAQSVHRGERIILDAE 687 Query: 1130 LT-KGDALVRWFKDGSEIQFS---NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++ + V WFKD +Q + L G KL D DAG++ N+ Sbjct: 688 VSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKLIFEQIDFADAGKFMIVARNT 745 Score = 40.3 bits (90), Expect = 0.57 Identities = 49/238 (20%), Positives = 92/238 (38%), Gaps = 27/238 (11%) Query: 1164 KIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR-LPEFILVPANTDAYLTVEIPD 1222 K C++ G E +S+ + + +PS+ L+ + F P D + + P+ Sbjct: 85 KSCSCNVVVKGRLPNETSDSELASDMEPVKPSVQLQLKDVSVFEGKPVRLDCVIVGQ-PE 143 Query: 1223 ETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 +V WY ++++ F L+ +L+IR+ +D EY V +++ K Sbjct: 144 P--EVIWYHGDRPVKESTDFQLLFQGDHCSLVIREAFLEDAGEYRVVAINSAGEASSKCS 201 Query: 1283 VVEFPPKIVD-------------------YER---EYRIKRGSDVTLLVDYQAFPQPNDE 1320 V+ P I + +ER + G P+PN + Sbjct: 202 VIVTPLNIAEPAVRQPAERILPALGAPPKFERLLSDILAAEGEKCQFECAVSGDPRPNIK 261 Query: 1321 WIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 W VN++ I++ + D L I++V D G+Y + N G A N+ + Sbjct: 262 WFVNNREIVENPRVHSVYRDDGVVKLIIEQVFPDDKGVYTAKAFNPSGEAKCFSNLIV 319 Score = 39.9 bits (89), Expect = 0.75 Identities = 29/158 (18%), Positives = 66/158 (41%), Gaps = 9/158 (5%) Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KSTTKLKVEVVEFPPKIVDY 1293 D E+ + + K + ++ + +D YT +A +T L V+ FPP Sbjct: 611 DGERIAVSYSLNKIVVELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRR 670 Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC----KHTKPSIDSKSASLTIKK 1349 + + RG + L + P+P W +++ +++ +T + + L ++ Sbjct: 671 LQAQSVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQV-GPTCKLIFEQ 729 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 ++ DAG + + N G A ++ +++ P +P Sbjct: 730 IDFADAGKFMIVARNTGGEAQSIADIAVMEAEQPQPQP 767 Score = 39.9 bits (89), Expect = 0.75 Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 ++ K ++N+ TN + R+ A A N + AS TT V+K++ I P + L+ Sbjct: 620 SLNKIVVELKNVSTNDAGRYTATASNA---AGASSTTADL-VVKKS-IFPPVFGRRLQAQ 674 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + E I L G P+P V W++D + ++ A Sbjct: 675 SVHRGERIILDAEVSGTPEPTVAWFKDNRPVQEA 708 Score = 37.9 bits (84), Expect = 3.0 Identities = 39/216 (18%), Positives = 84/216 (38%), Gaps = 14/216 (6%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKATYE-NRXXX 1535 +P P + D+ I G P P+V ++ +L+ +Y N+ Sbjct: 567 APRFVSPFNGKIVDQGADVAFEGIIDGYPTPEVKVTKNDVELQPDGERIAVSYSLNKIVV 626 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDEWLVT 1593 Y A N G T+ + +++ P + + H+ G+ ++ Sbjct: 627 ELKNVSTNDAGRYTATASNAAGASSTTADLVVKKSIFPPVFGRRLQAQSVHR-GERIILD 685 Query: 1594 AVIEGIPPPEVIWYKNGNKLE---NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 A + G P P V W+K+ ++ Y + T + +++ + + K+ I A NT Sbjct: 686 AEVSGTPEPTVAWFKDNRPVQEALRPGSYTLQQVGPTCKLIFEQIDFADAGKFMIVARNT 745 Query: 1651 AG--TSSVEVTLKVYDKPS-KPEGPVIMREISRESV 1683 G S ++ + ++P +P+ V ++ + +V Sbjct: 746 GGEAQSIADIAVMEAEQPQPQPQKHVSFIDVQKTTV 781 >UniRef50_Q6WRI0 Cluster: Immunoglobulin superfamily member 10 precursor; n=20; Mammalia|Rep: Immunoglobulin superfamily member 10 precursor - Homo sapiens (Human) Length = 2623 Score = 120 bits (289), Expect = 4e-25 Identities = 215/948 (22%), Positives = 368/948 (38%), Gaps = 101/948 (10%) Query: 645 VDEGSDILLECRLVAIPEPDIAW--LFKGEEIVP-DENISVAIESDMHMYCSVLKITNVK 701 + SD L C V P P I W + G ++ +N V + + L I V+ Sbjct: 1660 IPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN-----GTLSIQRVE 1714 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVG 760 G Y A N G L + L + + PP+++E K + V G +V L + G Sbjct: 1715 IQDRGQYLCSASNLFGTDHLHVTLSVVS---YPPRILERRTKEITVHSGSTVELKCRAEG 1771 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSIT------ILKPKKVKDEGVYTLKAENSEGIA 814 P PT+TW N+ V + S G ++ +L + D G Y A N G Sbjct: 1772 RPSPTVTWILANQTV--VSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGG-- 1827 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNN--E 871 + S ++ + + A PP+ + + +++ V G ++KL P PS+ W ++ E Sbjct: 1828 QDSLLVKI----QVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTE 1883 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 + T ++ F N L I N+ S D G Y+C+A++S G +T++ E+VT Sbjct: 1884 VKPLQFTNSKLFLFSNGTLYIRNLASS-DRGTYECIATSSTGSERRVVMLTME-ERVTSP 1941 Query: 932 K---HLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXX 984 + QK E G ++L C + + W K + HR I Sbjct: 1942 RIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSL 2001 Query: 985 XXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE---VKEKDVAILEV 1038 D GV C+ +++ ++++ ++ P I Q F + KD + Sbjct: 2002 FIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCK 2061 Query: 1039 EINSETADVVWE-RDGEIIKPKKNKYDFEKRGHIRK---------LYIRNTSVHDEGEYS 1088 S ++ W DG +I N + GH + LY V +EG+Y+ Sbjct: 2062 ASGSPVPEISWSLPDGTMI---NNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYT 2118 Query: 1089 C----ILRDESCTAEVTVVELPPEI-ITRLQNQKVNKGNKATFEIELTKGD--ALVRWFK 1141 C L + +TV+ P I + N+++ G+ A + E+T GD + W Sbjct: 2119 CYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVT-GDPKPKIFWLL 2177 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS- 1195 +++ S I L I L D+GEY C N +K + V +P Sbjct: 2178 PSNDM-ISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPL 2236 Query: 1196 IN--FTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKF-TLISDVKKR 1251 IN +T R ++ + + +V W ++ + + I+ K Sbjct: 2237 INGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG 2296 Query: 1252 TLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF---PPKIVDYEREYRIKRGSDVT 1306 TL IR D ++ CV + +S +++EV+E P + + + G Sbjct: 2297 TLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTA 2356 Query: 1307 LLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 L P P WI+ N + + + + S I K DAG Y+ N Sbjct: 2357 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNK 2416 Query: 1366 CGHADVEMNVTILDKP----SPPGKPNILEIDSSSINICWDE-PENTGNSTI-IYYVVEY 1419 G+ + + + I KP PG + +S S++ D P+ T+ YVV+ Sbjct: 2417 VGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDR 2476 Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETK 1478 +I+ ++I N T +K ++Y Y + + T V + Sbjct: 2477 PQIN-GKYILHDNGTLV------IKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTA 1525 I +P ++I T +L C+ GVP+P++TW D L TA Sbjct: 2530 I----TNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTA 2573 Score = 105 bits (251), Expect = 2e-20 Identities = 169/798 (21%), Positives = 304/798 (38%), Gaps = 64/798 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P ++ K V GS + L+CR P P + W+ + +V + S + Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSES--SQGSRQAVVTVD 1802 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV-RQGES 751 L + N+ + G Y VA N G+ SL + +++ PP ++E + +IV GES Sbjct: 1803 GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAA---PPVILEQRRQVIVGTWGES 1859 Query: 752 VILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 + L G P+P++ W ++ KP++ +K ++ ++ D G Y A Sbjct: 1860 LKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIA 1919 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 +S G ++T+EE P + + V + L T P P I W Sbjct: 1920 TSSTGSERRVVMLTMEERV---TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWR 1976 Query: 868 RNNEIISPSETITQNFDG--ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 ++ + + ++ N L I +V +E DSG Y CVA N G V++ + Sbjct: 1977 LPSKAVVDQQHRVGSWIHVYPNGSLFIGSV-TEKDSGVYLCVARNKMGDDLILMHVSLRL 2035 Query: 926 E--KVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKW-------YHNKKEISGMDHR- 973 + K+ ++ +K + GK ++C+ S + W +N + HR Sbjct: 2036 KPAKIDHKQYFRK--QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRT 2093 Query: 974 ---EIIQEGRXXXXXXXXXXXXDVGVI--KCIVKDQETSTMLVVKETIPEFIRKLQ-DFE 1027 + G D + KD E L V P + + + Sbjct: 2094 RRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKD-EMKVHLTVITAAPRIRQSNKTNKR 2152 Query: 1028 VKEKDVAILEVEINSE-TADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 +K D A+L+ E+ + + W ++I ++Y F G L I + D G Sbjct: 2153 IKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANG---SLTINKVKLLDSG 2209 Query: 1086 EYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKG-----NKATFE--IELTKGD 1134 EY C+ R D++ ++ VV PP I N+ V K +K F+ E T Sbjct: 2210 EYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSP 2269 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 ++ D + + K L+I + L D+ ++ C N ++L V+ Sbjct: 2270 EVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLE 2329 Query: 1195 SINF----TLRLP--EFILVPANTDAYLTVEIP-DETLDVTWYKKKSV-IEDTEKFTLIS 1246 + T R P E I+ L + + ++ W + + Sbjct: 2330 VLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYL 2389 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDY-EREYRIKRGSD 1304 + II K T +D +Y C + KL + + P I+ Y + G Sbjct: 2390 IASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGES 2449 Query: 1305 VTLLVDYQAFPQPNDEWIVNS-KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 ++L P+PN +W + S ++ + + I + +L IK+ D G Y + + Sbjct: 2450 LSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQ 2509 Query: 1364 NNCGHADVEMNVTILDKP 1381 N+ GH + + V I+ P Sbjct: 2510 NSVGHTLITVPVMIVAYP 2527 Score = 77.4 bits (182), Expect = 4e-12 Identities = 98/465 (21%), Positives = 183/465 (39%), Gaps = 25/465 (5%) Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 +PD T+ + T ++TL ++ TL K ++ +YTC + ++ Sbjct: 2074 LPDGTMINNAMQADDSGHRTRRYTLFNN---GTLYFNKVGVAEEGDYTCYAQNTLGKDEM 2130 Query: 1280 KVE--VVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 KV V+ P+I + RIK G L + P+P W++ S + + Sbjct: 2131 KVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRY 2190 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEIDS 1394 + + + SLTI KV+ D+G Y N G + ++ KP N I + Sbjct: 2191 TFHA-NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKA 2249 Query: 1395 SSINIC---WD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449 +++ +D E T + +++ + + + + S + K T I+N++ + S Sbjct: 2250 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 2309 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 F A NE S E ++++ ++P EK I + + L C G P Sbjct: 2310 DFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEK----IVAQLGKSTALNCSVDGNP 2365 Query: 1510 QPKVTWYR-DGKKLKTAKATYE----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 P++ W +G + +Y+ + Y+C A N G +E + Sbjct: 2366 PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 2425 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKEYNITT 1623 + I QKPVI ++ K G+ + V +GIP P + W +G ++ + Sbjct: 2426 LEIGQKPVI-LTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYI 2484 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + IKE Y +A N+ G + + V + + P + Sbjct: 2485 LHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529 Score = 76.2 bits (179), Expect = 9e-12 Identities = 99/405 (24%), Positives = 161/405 (39%), Gaps = 56/405 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 G +++ C +G P+P + W +KP Q + TL IR + D GT+ Sbjct: 1857 GESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYE 1916 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C+A ++ G L +E ++ P + K Sbjct: 1917 CIATSSTGSERRVVMLTMEERVTS--------------------------PRIEAASQKR 1950 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVK 701 V+ G +LL C P+P I W + +V ++ + S +H+Y + L I +V Sbjct: 1951 TEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQH---RVGSWIHVYPNGSLFIGSVT 2007 Query: 702 KFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 + G Y VA N+ G+ + + L++K + + Q V G+ + + Sbjct: 2008 EKDSGVYLCVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQ----VLHGKDFQVDCKAS 2063 Query: 760 GNPRPTITWCKNNKPV--KALPTKSDGD-THSITI-------LKPKKVKDEGVYTLKAEN 809 G+P P I+W + + A+ G T T+ V +EG YT A+N Sbjct: 2064 GSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQN 2123 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YR 868 + G E +TV A P + + +K T L VT +P P I W Sbjct: 2124 TLGKDEMKVHLTV-----ITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLP 2178 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +N++IS S I + N L I V +DSG+Y CVA N +G Sbjct: 2179 SNDMISFS--IDRYTFHANGSLTINKV-KLLDSGEYVCVARNPSG 2220 Score = 75.8 bits (178), Expect = 1e-11 Identities = 196/999 (19%), Positives = 355/999 (35%), Gaps = 91/999 (9%) Query: 733 EPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI-- 789 E P+++ S + L + VGNP PTI W + + K + + Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705 Query: 790 -TI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 T+ ++ +++D G Y A N G ++V + P + R +EITV Sbjct: 1706 GTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVV-----SYPPRILERRTKEITVHSG 1760 Query: 848 GTIKLVARVTRNPVPSITWYRNNEII--SPSETITQNFDGENIELVITNVDSEIDSGDYK 905 T++L R P P++TW N+ + S+ Q + LV+ N+ S D G YK Sbjct: 1761 STVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNL-SIYDRGFYK 1819 Query: 906 CVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKW-YH 962 CVASN G+ S ++ + ++ ++ G+++ L C T S W Sbjct: 1820 CVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLS 1879 Query: 963 NKKEISGMDH-REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI- 1020 + E+ + + D G +CI S VV T+ E + Sbjct: 1880 DGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVT 1939 Query: 1021 ------RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIR- 1072 + EV D +L E ++W + + ++++ + Sbjct: 1940 SPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNG 1999 Query: 1073 KLYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 L+I + + D G Y C+ R D+ V+ + L P I Q + + F++ Sbjct: 2000 SLFIGSVTEKDSGVYLCVARNKMGDDLILMHVS-LRLKPAKIDHKQYFRKQVLHGKDFQV 2058 Query: 1129 EL-TKGDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQK---------LKIYDCDLDDAGE 1175 + G + + W DG+ I +N +Q G + + L + + G+ Sbjct: 2059 DCKASGSPVPEISWSLPDGTMI--NNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGD 2116 Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWY 1230 Y+C +G + LTV + + A A L E+ D + W Sbjct: 2117 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWL 2176 Query: 1231 --KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF 1286 + +++T ++ +L I K D EY CV + T K++VV Sbjct: 2177 LPSNDMISFSIDRYTFHAN---GSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSK 2233 Query: 1287 PPKIVD-YEREYRIK----RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-S 1340 PP I Y IK R S + P P WI+ I + I Sbjct: 2234 PPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVH 2293 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD---KP---SPPGKPNILEIDS 1394 K+ +L I+ V +D+ + N G + + + + +L+ +P +P + + ++ Sbjct: 2294 KNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGK 2353 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT--NSSYRFR 1452 S+ C + II+ + S + + + S KT + ++R Sbjct: 2354 STALNC--SVDGNPPPEIIWILPNGTRFSNGPQ-SYQYLIASNGSFIISKTTREDAGKYR 2410 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A N+V + E I + + +K I+ E + L C+ G+P+P Sbjct: 2411 CAARNKVGYIEKLVILE----IGQKPVILTYAPGTVKGIS---GESLSLHCVSDGIPKPN 2463 Query: 1513 VTW-----YRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 + W Y + K + Y C A N G + V I Sbjct: 2464 IKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMI 2523 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL----ENDKEYNITT 1623 P + + G + + V G+P PE+ W + L ++ + Sbjct: 2524 VAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQ 2583 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + I+ + S S Y A N G+ ++V Sbjct: 2584 LHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622 Score = 66.5 bits (155), Expect = 8e-09 Identities = 100/441 (22%), Positives = 159/441 (36%), Gaps = 50/441 (11%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPED 577 K G T +C+V G P+P+I W +I S D ++ + +L I +V D Sbjct: 2151 KRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHAN---GSLTINKVKLLD 2207 Query: 578 AGTFTCVAKNAAGFASSTTEL-IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF 636 +G + CVA+N +G + +L +V P +G +++ Sbjct: 2208 SGEYVCVARNPSGDDTKMYKLDVVSKPPLING-------------LYTNRTVIKATAVRH 2254 Query: 637 SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 SKK +CR P P++ W+ + I + L+ Sbjct: 2255 SKKH------------FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKN---GTLE 2299 Query: 697 ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVILS 755 I NV+ + VA N GE+ L + L++ + P P IV Q G+S L+ Sbjct: 2300 IRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRR-PTFRNPFNEKIVAQLGKSTALN 2358 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSE 811 V GNP P I W N + +S S I K + +D G Y A N Sbjct: 2359 CSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTR-EDAGKYRCAARNKV 2417 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN--PVPSITWYRN 869 G E ++ E + P+ + + TVK L + P P+I W Sbjct: 2418 GYIEKLVIL-------EIGQKPVILT-YAPGTVKGISGESLSLHCVSDGIPKPNIKWTMP 2469 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + I + + ++ + D G+Y C A NS G + V I Sbjct: 2470 SGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529 Query: 930 FVKHLQKSYETEEGKTVILEC 950 +S T G L C Sbjct: 2530 ITNRPPRSIVTRTGAAFQLHC 2550 Score = 59.3 bits (137), Expect = 1e-06 Identities = 77/292 (26%), Positives = 111/292 (38%), Gaps = 28/292 (9%) Query: 634 PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PTF + V + G L C + P P+I W+ S +S ++ Sbjct: 2337 PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPN-----GTRFSNGPQSYQYLIA 2391 Query: 693 S--VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QG 749 S I+ + G Y A N+ G ++L+I G+K P ++ + G Sbjct: 2392 SNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEI--GQK--PVILTYAPGTVKGISG 2447 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLK 806 ES+ L G P+P I W + V P K + ++K D G Y K Sbjct: 2448 ESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICK 2507 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT 865 A+NS G +ITV P A PP NR V G +L P P IT Sbjct: 2508 AQNSVG----HTLITV--PVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEIT 2561 Query: 866 WYRNNEIISPSETITQNFDGENIEL----VITNVDSEIDSGDYKCVASNSAG 913 W + + + + + E + L VI N + DSG YKC A N G Sbjct: 2562 WEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTS-DSGIYKCTAKNPLG 2612 Score = 48.8 bits (111), Expect = 0.002 Identities = 86/406 (21%), Positives = 156/406 (38%), Gaps = 39/406 (9%) Query: 1288 PKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSAS 1344 P+IV + + I SD L + P P W + + + K K + + Sbjct: 1648 PRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGT 1707 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 L+I++VE D G Y N G + + ++++ P P ILE + I + Sbjct: 1708 LSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYP-----PRILERRTKEITV----- 1757 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD- 1463 ++G++ + E + T WI + N T S Q + ++ + I D Sbjct: 1758 -HSGSTVELKCRAEGRPSPTVTWI-LANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDR 1815 Query: 1464 -------ASETTEYYKVIKETKIQSPTV--EKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 ++ + ++K I +P V E+ + I E ++L C G PQP V Sbjct: 1816 GFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVY 1875 Query: 1515 W-YRDGKKLKTAKATYE-----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 W DG ++K + T + Y+CIA + G E V+ Sbjct: 1876 WVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGS-ERRVVMLTM 1934 Query: 1569 QKPVITISNEDIKQKH---KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-- 1623 ++ V + E QK GD+ L+ G P P+++W + +K D+++ + + Sbjct: 1935 EERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMW-RLPSKAVVDQQHRVGSWI 1993 Query: 1624 -KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + I + S Y A N G + + + + KP+K Sbjct: 1994 HVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLKPAK 2039 Score = 48.0 bits (109), Expect = 0.003 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 4/83 (4%) Query: 524 GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 GSTV+ +C+ EG P P +TW QT + + SQ + + TLV+ + D G + Sbjct: 1760 GSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVD-GTLVLHNLSIYDRGFY 1818 Query: 582 TCVAKNAAGFASSTTEL-IVEAP 603 CVA N G S ++ ++ AP Sbjct: 1819 KCVASNPGGQDSLLVKIQVIAAP 1841 Score = 47.2 bits (107), Expect = 0.005 Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 17/184 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L C IP+P+I W +V I+ + +H L I + G Sbjct: 2447 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQING--KYILHDN-GTLVIKEATAYDRGN 2503 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTI 766 Y A N G + + + I PP++ P +S++ R G + L +G P+P I Sbjct: 2504 YICKAQNSVGHTLITVPVMIVA---YPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEI 2560 Query: 767 TWCKNNKPVKALPTKSDGDTH--------SITILKPKKVKDEGVYTLKAENSEGIAETSA 818 TW + + L T S TH +++ + D G+Y A+N G + Sbjct: 2561 TWEMPDHSL--LSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAAT 2618 Query: 819 VITV 822 I V Sbjct: 2619 YIQV 2622 Score = 44.4 bits (100), Expect = 0.035 Identities = 48/209 (22%), Positives = 77/209 (36%), Gaps = 15/209 (7%) Query: 1497 EDIELTCIFGGVPQPKVTW-YRDGKKL-----------KTAKATYENRXXXXXXXXXXXX 1544 +D ++ C G P P+++W DG + +T + T N Sbjct: 2054 KDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAE 2113 Query: 1545 XXXYKCIAFNDHGEVETSC-VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 Y C A N G+ E + I P I SN+ K + K GD ++ + G P P+ Sbjct: 2114 EGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNK-RIKAGDTAVLDCEVTGDPKPK 2172 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 + W N + + T S + I ++K S +Y A N +G + L V Sbjct: 2173 IFWLLPSNDMISFSIDRYTFHANGS-LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVV 2231 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLD 1692 KP G R + + + K D Sbjct: 2232 SKPPLINGLYTNRTVIKATAVRHSKKHFD 2260 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV---ATLVIREVFPED 577 T G+ Q C G P+P+ITW + + + + + + TLVI+ D Sbjct: 2540 TRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSD 2599 Query: 578 AGTFTCVAKNAAGFASSTTELIV 600 +G + C AKN G + T + V Sbjct: 2600 SGIYKCTAKNPLGSDYAATYIQV 2622 Score = 37.5 bits (83), Expect = 4.0 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 4/92 (4%) Query: 502 TSEEQSMAPIFVEKLRPKHTPD--GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQM 558 T EE+ +P +E K T G + C G P+PQI W A++ Sbjct: 1933 TMEERVTSPR-IEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGS 1991 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 + +L I V +D+G + CVA+N G Sbjct: 1992 WIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG 2023 Score = 36.7 bits (81), Expect = 7.0 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 524 GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 G T+ C G P I+W + + S+D ++ N TL I +V P+D G + Sbjct: 588 GETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVL----NNGTLRILQVTPKDQGYY 643 Query: 582 TCVAKNAAG 590 CVA N +G Sbjct: 644 RCVAANPSG 652 >UniRef50_A0RX14 Cluster: Putative uncharacterized protein; n=1; Cenarchaeum symbiosum|Rep: Putative uncharacterized protein - Cenarchaeum symbiosum Length = 506 Score = 118 bits (285), Expect = 1e-24 Identities = 95/359 (26%), Positives = 154/359 (42%), Gaps = 25/359 (6%) Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE--ISRES 1682 +KTS L + Y I A N G S V +KP+ + PV + +S S Sbjct: 40 QKTSYTHTA-LSSGETYSYKIYAKNQHGESRASNI--VSEKPAGTQSPVKLTATGLSPTS 96 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 ++W P D GL++ Y+IE+ NN ++ + + L + EY FRV Sbjct: 97 ARLDWFAPSDTVGLKIVSYSIERLT-SNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVF 155 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX------XXIDNESVYITWFPSEKNGG 1796 A G S +SEP+V D ++ V +TW NGG Sbjct: 156 AHLTQGVSSP-KSEPVVFTLTEDSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGG 214 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS---INTTYQFRIYARNEIGTSLPYTS 1853 +PI Y+++++ +G ++ +R + T Y +R+YA N+IG+ P T Sbjct: 215 TPITGYRIDVRSDGN-YETIEADTGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPPTTE 273 Query: 1854 DDKITIGK----TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG 1909 T + L PS PRN S S+S + LKW EP +GG+ I+ Y +E + G Sbjct: 274 VSVTTAAEPEEPVLAAPSSPRNLEASASSSDRIDLKWVEPADDGGARISEYRLEADS--G 331 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 + +I GG + +++ + +R+ A N+ G S P+ + S E+ P Sbjct: 332 DGFERI--SGGRSTTYAHMGLEQDTKYTYRVYATNSEGTSSPSVAASATTEEEEEPEDP 388 Score = 96.3 bits (229), Expect = 8e-18 Identities = 91/379 (24%), Positives = 151/379 (39%), Gaps = 22/379 (5%) Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 I W+ P + G + T Y I+ D + + + D + +Y L+ Y +++ A+ Sbjct: 4 ISWEEPTANDGPKATGYRIDYKTRDGD-YTTLIDDNGQKTSYTHTALSSGETYSYKIYAK 62 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N G S A S + K A + + S + WF G I+ Y + Sbjct: 63 NQHGESRA--SNIVSEKPA---GTQSPVKLTATGLSPTSARLDWFAPSDTVGLKIVSYSI 117 Query: 1805 EIKQEGKKWKXX--XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI--- 1859 E + + + L + Y+FR++A G S P + T+ Sbjct: 118 ERLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLTED 177 Query: 1860 -GKTLT-PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT 1917 GK + P P + V+ S+ V+L W EP +NGG+PIT Y I+ ++ G T Sbjct: 178 SGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRS-DGNYETIEAD 236 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL--EKHATVPSPPTAP--L 1973 G + + + + E +R+ A N +G PT SV E V + P++P L Sbjct: 237 TGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPPTTEVSVTTAAEPEEPVLAAPSSPRNL 296 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSE 2033 E S+ + W P DGGA + Y + + G+ + + L + Sbjct: 297 EASASSSDRIDLKWVEPADDGGARISEYRLEADSGDGFERISGGR----STTYAHMGLEQ 352 Query: 2034 NHTYMIRIYARNEIGLSEP 2052 + Y R+YA N G S P Sbjct: 353 DTKYTYRVYATNSEGTSSP 371 Score = 70.1 bits (164), Expect = 6e-10 Identities = 64/276 (23%), Positives = 100/276 (36%), Gaps = 14/276 (5%) Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQK--LSINTTYQFRIYA 1841 ++I+W N G Y+++ K + LS TY ++IYA Sbjct: 2 LHISWEEPTANDGPKATGYRIDYKTRDGDYTTLIDDNGQKTSYTHTALSSGETYSYKIYA 61 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 +N+ G S + G P + + S L W P G I +Y Sbjct: 62 KNQHGESRASNIVSEKPAGT-----QSPVKLTATGLSPTSARLDWFAPSDTVGLKIVSYS 116 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL-- 1959 IE + + G S + N++ E FR+ A T GVS P V Sbjct: 117 IE-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLT 175 Query: 1960 -EKHATVPSPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + V P +P +++ S+ V +W P +GG P+ GY I +R +E Sbjct: 176 EDSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRSDGNYETIE- 234 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + + D Y R+YA N+IG P Sbjct: 235 ADTGSTSRSYTHTDRVAETEYTYRVYAINKIGSGPP 270 Score = 54.8 bits (126), Expect = 2e-05 Identities = 43/215 (20%), Positives = 79/215 (36%), Gaps = 7/215 (3%) Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 + W EP +N G T Y I++KT G +T ++ G + + + ++I A+ Sbjct: 4 ISWEEPTANDGPKATGYRIDYKTRDG-DYTTLIDDNGQKTSYTHTALSSGETYSYKIYAK 62 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 N G S + ++ EK A SP L + W P G ++ Y+I Sbjct: 63 NQHGES---RASNIVSEKPAGTQSP--VKLTATGLSPTSARLDWFAPSDTVGLKIVSYSI 117 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 R + ++++ K + + +L + Y R++A G+S P F + Sbjct: 118 E-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRVFAHLTQGVSSPKSEPVVFTLTE 176 Query: 2064 GEGSHADEEPGEQTEVXXXXXXXXXXXXXWLREHN 2098 G + + P + W N Sbjct: 177 DSGKNVERSPESPGSLQVTSSSHDQVSLTWNEPSN 211 Score = 40.3 bits (90), Expect = 0.57 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 7/108 (6%) Query: 1384 PGKPNILEIDSSS---INICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTS 1439 P P L++ SSS +++ W+EP N G + I Y ++ + E I T + Sbjct: 186 PESPGSLQVTSSSHDQVSLTWNEPSNNGGTPITGYRIDVRSDGNYETIEADTGSTSRSYT 245 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 + + Y +R YA+N+ I TTE V + + P + P Sbjct: 246 HTDRVAETEYTYRVYAINK--IGSGPPTTE-VSVTTAAEPEEPVLAAP 290 Score = 37.5 bits (83), Expect = 4.0 Identities = 34/171 (19%), Positives = 73/171 (42%), Gaps = 10/171 (5%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---PPGKPNILEIDSS 1395 + + S T + + + YK+ +N H + + + +KP+ P K + + Sbjct: 38 NGQKTSYTHTALSSGETYSYKIYAKNQ--HGESRASNIVSEKPAGTQSPVKLTATGLSPT 95 Query: 1396 SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTNSSYRFRA 1453 S + W P +T I+ Y +E + ++ + + TS + NL+T+ YRFR Sbjct: 96 SARLDWFAPSDTVGLKIVSYSIE-RLTSNNVFLDAEKTGSSDTSSILNNLETDKEYRFRV 154 Query: 1454 YAVNEVDISDASETTEYYKVIKET-KIQSPTVEKP-LKNITTEPNEDIELT 1502 +A +S + + +++ K + E P +T+ ++ + LT Sbjct: 155 FAHLTQGVSSPKSEPVVFTLTEDSGKNVERSPESPGSLQVTSSSHDQVSLT 205 >UniRef50_Q4S8U5 Cluster: Chromosome 7 SCAF14703, whole genome shotgun sequence; n=5; Tetraodontidae|Rep: Chromosome 7 SCAF14703, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2095 Score = 118 bits (284), Expect = 2e-24 Identities = 172/815 (21%), Positives = 320/815 (39%), Gaps = 71/815 (8%) Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784 L + + P +++ ++ V G+S+ L G P PT+ W K+ +P LP+ + Sbjct: 219 LSVMDPNESSPTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRP---LPSDARW 275 Query: 785 DTHSIT--ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI 842 T +T + +++D G Y + NS G E S + V +P P + + Sbjct: 276 -TRRLTGLTISDLRLEDSGSYACEVTNSFGSKEVSGQLHVIDPLRVTLSP-------KNL 327 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902 T+ V +P +ITW+RN E+I P + I + G+N + + + SG Sbjct: 328 KTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHI--SIQGQNNDTLQITAAQKFHSG 385 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHL-QKSYETEEGKTVILECQTSHTVSTKWY 961 Y+C AS + + + ++ V ++ E +++ + + S W Sbjct: 386 AYQCFASRKGHTAQDFSIILLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWT 445 Query: 962 HNKKEI----SGMDHREIIQEGRXXXXXXXXX-XXXDVGVIKCIVKDQETSTMLVVKETI 1016 + + + + + + +G D GV +C+ ++ S + + Sbjct: 446 LDDEPVVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINV 505 Query: 1017 --PEFIRKLQDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 P IR ++D V ++ I I + W +DG + + FE G +R Sbjct: 506 RGPPRIRPMRDMTAVAGRNTYITCRVIGYPYYSIKWLKDGMQLPDNHRQVVFE-NGTLRL 564 Query: 1074 LYIRNTSVHDEGEYSC-ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIE 1129 ++ + DEG Y C +L + TV V++PP +I + G Sbjct: 565 TDVQKGA--DEGTYLCSVLIQPQVSINQTVHVTVKVPP-LIQPFDIPSTSVGKLIYIACV 621 Query: 1130 LTKGDALVR--WFKDGSEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCEVGNSKC 1185 ++ GD +R W KDG I + + I+ K L+I L G Y+C N Sbjct: 622 VSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASN--- 678 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDA-YLTVEIPDETLD------VTWYKKKSVIED 1238 TA E + T+ P F++ P N D Y + + +++ V W K V Sbjct: 679 TAATVSWERQLIVTVP-PRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNP 737 Query: 1239 TEKFTL-----ISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE---VVEFPPKI 1290 + + I + +L+IR E+D+ Y C + + + V+ P I Sbjct: 738 QQYHPVPLTGRIQIMSNGSLLIRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMI 797 Query: 1291 VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI------DSKSAS 1344 + ++G L + W +I ++ + SI D ++ Sbjct: 798 TSHPNTTMARKGQTKELNCTARGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVIST 857 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEP 1404 L + E D+ + N+ G + +T+ + P PP + + E+ S+N+ W + Sbjct: 858 LKLNPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPP-ELEVREVKDRSMNLRWIQ- 915 Query: 1405 ENTGNSTIIYYVVEYQEIDTTEW---ISVKNI--TKTQTSIQNLKTNSSYRFRAYAVNEV 1459 GNS I Y +EY+ + W + +NI T Q +I L Y R Y+ N++ Sbjct: 916 RFDGNSIITSYDIEYKN-KSDSWDHMYTTRNISPTNNQANIVELHPACVYSIRMYSYNKI 974 Query: 1460 DISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 S S+ E +E P ++ L+ +T++ Sbjct: 975 GRSLPSK--ELTISTEEAPPDGPPMDVILQPMTSQ 1007 Score = 105 bits (251), Expect = 2e-20 Identities = 212/1054 (20%), Positives = 387/1054 (36%), Gaps = 117/1054 (11%) Query: 1074 LYIRNTSVHDE-GEYSCILRD-------ESCTAEVTVV---ELPPEIITRLQNQKVNKGN 1122 LYI D Y CI R +S A ++V+ E P I+ Q +V G Sbjct: 185 LYISEVQKEDALSTYRCITRHKYSGETRQSNGARLSVMDPNESSPTILDSFQAGEVYAGQ 244 Query: 1123 KATFEIELTKG---DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 + E+ G + VRW KDG + + G L I D L+D+G Y+CE Sbjct: 245 --SIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG----LTISDLRLEDSGSYACE 298 Query: 1180 VGNS----KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKS 1234 V NS + + L V +P + TL P+ + ++ + T + +TW++ Sbjct: 299 VTNSFGSKEVSGQLHVIDP-LRVTLS-PKNLKTGISSTLFFTCSVEGSPEYTITWFRNTE 356 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIV 1291 +I + + I TL I + Y C K T ++ + P+IV Sbjct: 357 LIVPDQHIS-IQGQNNDTLQITAAQKFHSGAYQC-FASRKGHTAQDFSIILLEDGTPRIV 414 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 E + G +L+ + P P+ W ++ + + + K S + S LT+ V Sbjct: 415 SSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVSHVN 474 Query: 1352 NT-----DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 + D G+Y+ N+ G A+ + + + P ++ + + I Sbjct: 475 VSSPHIRDGGVYRCVARNSAGSAEYQARINVRGPPRIRPMRDMTAVAGRNTYITC-RVIG 533 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 +I + Q D + +N T T +Q +Y +V I+ Sbjct: 534 YPYYSIKWLKDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSINQTVH 593 Query: 1467 TTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA 1525 T ++ P + +P +T + I + C+ P ++TW++DG+ + Sbjct: 594 VT----------VKVPPLIQPFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPG 643 Query: 1526 KA------TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV--ETSCVVGIQQKPVITISN 1577 A T + Y CIA N V E +V + + V+ +N Sbjct: 644 SASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNN 703 Query: 1578 EDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN---ITTK---EKTSVIR 1631 +D G ++ +EG PPP+V+W K+ + N ++Y+ +T + + Sbjct: 704 QDC----IYGKAGVLNCSVEGYPPPKVMW-KHAKGVGNPQQYHPVPLTGRIQIMSNGSLL 758 Query: 1632 IKELKRSHSSKYTIEASNTAGTS-SVE---VTLKVYDK-PSKPEGPVIMREISRE-SVTI 1685 I+ + Y +ASN G+ S E VT+K+ S P + + ++E + T Sbjct: 759 IRHVLEEDRGYYLCQASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKGQTKELNCTA 818 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN 1745 + P+ + P + I D + T + F A N Sbjct: 819 RGEQPIIIRWERGDTVIDAERNPRYSITINKKG-DEVISTLKLNPAERGDSVFFSCHAIN 877 Query: 1746 PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G L + ++ D P + + S+ + W +G S I Y +E Sbjct: 878 SYGEGRGLIQ--LTVQEPPDPPE-----LEVREVKDRSMNLRWI-QRFDGNSIITSYDIE 929 Query: 1806 IKQEGKKWKXXXXX-----XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 K + W A I +L Y R+Y+ N+IG SLP ++TI Sbjct: 930 YKNKSDSWDHMYTTRNISPTNNQANIVELHPACVYSIRMYSYNKIGRSLP---SKELTIS 986 Query: 1861 KTLTPP-SQPRNFVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKT----VKGKSWTK 1914 PP P + ++ TS+S+ + W P+ I Y I ++ G+ Sbjct: 987 TEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGYQIGYRENGPGSNGQYSIV 1046 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV--------SLPTESQSVRLEKHATV- 1965 + G + ++N+K+ + + A N G + E + R ++ + + Sbjct: 1047 EMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSTEINATTLEDEDARKQRPSAIT 1106 Query: 1966 -------PSPPTAPLEIRMVG--SNIVMTSWG-TPEWDGGAPLLGYNIAIRDV-TKTMWM 2014 P P P +R + S+ + +W P L GY + + + W Sbjct: 1107 DSYPPLFPVPSEPPQNVRAISVTSDEAVITWSEPPRLTLHGVLKGYRVVFWSLFSNGEWG 1166 Query: 2015 EVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 E+ + + +R L + Y +++ A + G Sbjct: 1167 EMQNITTTREQVELRGLEKFTNYSVQVLAYTQAG 1200 Score = 97.1 bits (231), Expect = 5e-18 Identities = 177/845 (20%), Positives = 320/845 (37%), Gaps = 96/845 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT +A V G I L C P P + WL G + D + + Sbjct: 229 PTILDSFQAGEVYAGQSIELPCIAGGYPNPTVRWLKDGRPLPSDARWTRRLTG------- 281 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I++++ G+Y N G + L + +P +V K++ ++ Sbjct: 282 -LTISDLRLEDSGSYACEVTNSFGSKEVSGQLHVI----DPLRVTLSPKNLKTGISSTLF 336 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + V G+P TITW +N + + S G + + + G Y A Sbjct: 337 FTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQKFHSGAYQCFASRKGH 396 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE- 871 A+ ++I +E+ T P ++ F E V L+ P PSITW ++E Sbjct: 397 TAQDFSIILLEDGT------PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEP 450 Query: 872 IISPSETITQNF---DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 ++ S T + DG + V + D G Y+CVA NSAG + + AR I+V Sbjct: 451 VVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQAR--INVRGP 508 Query: 929 TFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXX 986 ++ + + G+ + C+ S KW + ++ +HR+++ E Sbjct: 509 PRIRPM-RDMTAVAGRNTYITCRVIGYPYYSIKWLKDGMQLPD-NHRQVVFE-NGTLRLT 565 Query: 987 XXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVA-ILEVEINSETA 1045 D G C V Q ++ + +Q F++ V ++ + + Sbjct: 566 DVQKGADEGTYLCSVLIQPQVSINQTVHVTVKVPPLIQPFDIPSTSVGKLIYIACVVSSG 625 Query: 1046 D----VVWERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA-- 1098 D + W +DG+ I P + E + + L I ++ G Y+CI + + T Sbjct: 626 DMPIRITWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSW 685 Query: 1099 -EVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKD---GSEIQF----- 1148 +V +PP + + NQ G + V W G+ Q+ Sbjct: 686 ERQLIVTVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPL 745 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILV 1208 + IQ+ +G L I +D G Y C+ N + I + + T+++P I Sbjct: 746 TGRIQIMSNG---SLLIRHVLEEDRGYYLCQASNGVGSDISREHD---HVTVKIPAMITS 799 Query: 1209 PANTDAY---LTVEI-----PDETLDVTWYKKKSVI--EDTEKFTLISDVKK----RTLI 1254 NT T E+ ++ + + W + +VI E ++++ + K TL Sbjct: 800 HPNTTMARKGQTKELNCTARGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLK 859 Query: 1255 IRKCTEDDQCEYTCVLL----DAKSTTKLKVEVVEFPPKIVDYEREYR------IKRGSD 1304 + D ++C + + + +L V+ PP++ E + R I+R Sbjct: 860 LNPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPPELEVREVKDRSMNLRWIQRFDG 919 Query: 1305 VTLLVDYQ-AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL- 1362 +++ Y + +D W +T +I + I VE A +Y +R+ Sbjct: 920 NSIITSYDIEYKNKSDSW--------DHMYTTRNISPTNNQANI--VELHPACVYSIRMY 969 Query: 1363 -ENNCGHADVEMNVTILDKPSPPGKPN---ILE-IDSSSINICWDEP-ENTGNSTIIYYV 1416 N G + +TI + +PP P IL+ + S SI + W P + N I Y Sbjct: 970 SYNKIGRSLPSKELTISTEEAPPDGPPMDVILQPMTSQSIRVTWRAPKKELQNGVIRGYQ 1029 Query: 1417 VEYQE 1421 + Y+E Sbjct: 1030 IGYRE 1034 Score = 89.0 bits (211), Expect = 1e-15 Identities = 135/602 (22%), Positives = 226/602 (37%), Gaps = 65/602 (10%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P + PK S + C + PE I W E IVPD++IS+ +++ Sbjct: 317 PLRVTLSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNN----- 371 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L+IT +KF G Y A +R+G + + + E P+++ +V GE Sbjct: 372 DTLQITAAQKFHSGAYQCFA-SRKGHTAQDFSIILL--EDGTPRIVSSFSERVVNPGEPF 428 Query: 753 ILSAQVVGNPRPTITWCKNNKPV-------KALPTKSDGDTHSITILKPKKVKDEGVYTL 805 L G P P+ITW +++PV + T SDG T S + ++D GVY Sbjct: 429 SLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTVSHVNVSSPHIRDGGVYRC 488 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A NS G AE A I V P I +++T + RV P SI Sbjct: 489 VARNSAGSAEYQARINVRGPPR--------IRPMRDMTAVAGRNTYITCRVIGYPYYSIK 540 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVTID 924 W ++ + + + EN L +T+V D G Y C V + VT+ Sbjct: 541 WLKDGMQLPDNH---RQVVFENGTLRLTDVQKGADEGTYLCSVLIQPQVSINQTVHVTVK 597 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGMDHREIIQEGR- 980 V + + T GK + + C S + W+ + + I + E + Sbjct: 598 VPPLIQPFDIP---STSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKD 654 Query: 981 -XXXXXXXXXXXXDVGVIKCIVKDQETST---MLVVKETIPEFIRKLQDFEVKEKDVAIL 1036 G CI + + ++ P F+ + + + +L Sbjct: 655 FMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQPNNQDCIYGKAGVL 714 Query: 1037 EVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIR-----KLYIRNTSVHDEGEYSC- 1089 + V+W+ + P++ + G I+ L IR+ D G Y C Sbjct: 715 NCSVEGYPPPKVMWKHAKGVGNPQQ-YHPVPLTGRIQIMSNGSLLIRHVLEEDRGYYLCQ 773 Query: 1090 ----ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGD--ALVRWFKD 1142 + D S + V++P I + KG T E+ T +G+ ++RW + Sbjct: 774 ASNGVGSDISREHDHVTVKIPAMITSHPNTTMARKGQ--TKELNCTARGEQPIIIRWERG 831 Query: 1143 GSEIQFSNH--IQLTIDGKKQK----LKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192 + I + +TI+ K + LK+ + D+ +SC G + LTV+ Sbjct: 832 DTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDSVFFSCHAINSYGEGRGLIQLTVQ 891 Query: 1193 EP 1194 EP Sbjct: 892 EP 893 Score = 68.1 bits (159), Expect = 2e-09 Identities = 77/344 (22%), Positives = 134/344 (38%), Gaps = 23/344 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IES 686 +LE P + V+ G L C P P I W E +V D + Sbjct: 405 LLEDGTPRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTL 464 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + S + +++ G Y VA N G A + + + PP+ I P++ M Sbjct: 465 SDGLTVSHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINV----RGPPR-IRPMRDMTA 519 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 G + ++ +V+G P +I W K+ + + + ++ + +K DEG Y Sbjct: 520 VAGRNTYITCRVIGYPYYSIKWLKDGMQLPDNHRQVVFENGTLRLTDVQKGADEGTYLCS 579 Query: 807 AENSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SI 864 ++ V +TV+ PPL I F + I + V+ +P I Sbjct: 580 VLIQPQVSINQTVHVTVK-------VPPL-IQPFDIPSTSVGKLIYIACVVSSGDMPIRI 631 Query: 865 TWYRNNEIISPSETITQNFDGENI--ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 TW+++ + I P + ++ L IT V + +G+Y C+ASN+A S ++ Sbjct: 632 TWHKDGQPIVPGSASGVAIETKDFMSSLQITKVTLK-HNGNYTCIASNTAATVSWERQLI 690 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNK 964 + V V+ + + GK +L C K W H K Sbjct: 691 VTVPPRFVVQ--PNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAK 732 Score = 51.6 bits (118), Expect = 2e-04 Identities = 74/336 (22%), Positives = 133/336 (39%), Gaps = 25/336 (7%) Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI- 1678 NITT + + ++ L++ + + A AG L + + P P ++ + Sbjct: 1170 NITTTREQ--VELRGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDLPGPPAGIKAVP 1227 Query: 1679 -SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCE 1736 S SV + W PP G+ + KY I P + + + + ++ Y I L+ + Sbjct: 1228 SSPSSVVVSWLPPNKPNGI-IRKYTIYCSSPGSGQPAPSEYEANPEMLFYRITHLSRGKQ 1286 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGG 1796 Y A G S + ++ A VP+ +V W + Sbjct: 1287 YHIWAAAVTTAGKGNF--SSKVTVEPAGKVPAKILSFGG-------TVTTPWMKEVRLPC 1337 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG----TSLPYT 1852 S + + IK K + ++ Q LS N T R + G T+ Sbjct: 1338 SSVGEPAPTIKWT-KDSEDSAVPVTSDSQRQVLS-NGTLVLRSVKAEDSGYYTCTATNTL 1395 Query: 1853 SDDKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 D I + + PP QPR V + STS S+TL W P NGGS I +++++ + Sbjct: 1396 GFDTIIVNLVVQVPPDQPRLTVSTTSTS-SITLAWI-PGDNGGSSIRGFVLQYSVDNTEE 1453 Query: 1912 WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 W + V + + ++N++ +++A+N+VG Sbjct: 1454 W-RDVFISSTERSFKLDNLRCGTWYKVKLAAKNSVG 1488 Score = 50.4 bits (115), Expect = 5e-04 Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 16/167 (9%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR-----IKELKRSHSSKYTIEASNTAG 1652 G P P + W K+ D +T+ + V+ ++ +K S YT A+NT G Sbjct: 1341 GEPAPTIKWTKDSE----DSAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTLG 1396 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 ++ V L V P +P + + S S+T+ W P D+GG + + ++ + Sbjct: 1397 FDTIIVNLVVQVPPDQPR--LTVSTTSTSSITLAWIPG-DNGGSSIRGFVLQYSVDNTEE 1453 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756 W V + ++ + L Y ++ A+N VG SE +E++ Sbjct: 1454 WRDVF-ISSTERSFKLDNLRCGTWYKVKLAAKNSVGSGRISEIIEAK 1499 Score = 49.6 bits (113), Expect = 0.001 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 5/137 (3%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +IT++ + ++ AV G+ + + ++ K P +++ ++ + V L Sbjct: 1277 RITHLSRGKQYHIWAAAVTTAGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKEVRLP 1336 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVYTLKAENSE 811 VG P PTI W K+++ A+P SD ++ +L+ K +D G YT A N+ Sbjct: 1337 CSSVGEPAPTIKWTKDSED-SAVPVTSDSQRQVLSNGTLVLRSVKAEDSGYYTCTATNTL 1395 Query: 812 GIAETSAVITVEEPTEE 828 G + V+ P ++ Sbjct: 1396 GFDTIIVNLVVQVPPDQ 1412 Score = 48.8 bits (111), Expect = 0.002 Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 TP V+ C G P P I W + + + + + D Q + TLV+R V ED+ Sbjct: 1327 TPWMKEVRLPCSSVGEPAPTIKWTKDSEDSAVPVTSDSQRQVLSNG--TLVLRSVKAEDS 1384 Query: 579 GTFTCVAKNAAGFASSTTELIVEAP 603 G +TC A N GF + L+V+ P Sbjct: 1385 GYYTCTATNTLGFDTIIVNLVVQVP 1409 Score = 48.0 bits (109), Expect = 0.003 Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 4/88 (4%) Query: 516 LRPKHTPDG--STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV 573 L PK+ G ST+ F C VEG P ITWFR T +I P Q + +++ + + Sbjct: 322 LSPKNLKTGISSTLFFTCSVEGSPEYTITWFRNTELIVPDQHISIQGQNNDTLQITAAQK 381 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601 F +G + C A A + +++E Sbjct: 382 F--HSGAYQCFASRKGHTAQDFSIILLE 407 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD--- 563 ++ P FV + + G C VEGYP P++ W + P Q + Sbjct: 692 TVPPRFVVQPNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRIQI 751 Query: 564 -NVATLVIREVFPEDAGTFTCVAKNAAG 590 + +L+IR V ED G + C A N G Sbjct: 752 MSNGSLLIRHVLEEDRGYYLCQASNGVG 779 Score = 39.1 bits (87), Expect = 1.3 Identities = 52/224 (23%), Positives = 97/224 (43%), Gaps = 10/224 (4%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK--EPPQVIEPLKSMIVRQGESV 752 +++ ++KF + V+A + G+ VL I+T E PP I+ + S S Sbjct: 1178 VELRGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDLPGPPAGIKAVPSSPSSVVVSW 1237 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI--TILKPKKVKDEGVYTLKAENS 810 + + G R +C + + P++ + + + I + K ++ A + Sbjct: 1238 LPPNKPNGIIRKYTIYCSSPGSGQPAPSEYEANPEMLFYRITHLSRGKQYHIWAA-AVTT 1296 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G S+ +TVE + A+ F +KE ++L P P+I W +++ Sbjct: 1297 AGKGNFSSKVTVEPAGKVPAKILSFGGTVTTPWMKE---VRLPCSSVGEPAPTIKWTKDS 1353 Query: 871 EIIS-PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 E + P + +Q N LV+ +V +E DSG Y C A+N+ G Sbjct: 1354 EDSAVPVTSDSQRQVLSNGTLVLRSVKAE-DSGYYTCTATNTLG 1396 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 4/98 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYY---DDDNV 565 P V + G C +G P P ITW +++ S Y D V Sbjct: 411 PRIVSSFSERVVNPGEPFSLMCAAKGAPPPSITWTLDDEPVVRDSTYKTSQYTLSDGLTV 470 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + + D G + CVA+N+AG A + V P Sbjct: 471 SHVNVSSPHIRDGGVYRCVARNSAGSAEYQARINVRGP 508 Score = 37.9 bits (84), Expect = 3.0 Identities = 84/403 (20%), Positives = 143/403 (35%), Gaps = 42/403 (10%) Query: 584 VAKNAAGFASSTTELIVEAPLSD----HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 V +A+G A T + + ++ H T ++ +PP F + Sbjct: 641 VPGSASGVAIETKDFMSSLQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVPPRFVVQ 700 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH-MYCSVLKIT 698 P Q G +L C + P P + W P + V + + M L I Sbjct: 701 PNNQDCIYGKAGVLNCSVEGYPPPKVMWKHAKGVGNPQQYHPVPLTGRIQIMSNGSLLIR 760 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 +V + G Y A N G + K P + + + R+G++ L+ Sbjct: 761 HVLEEDRGYYLCQASNGVGSDISREHDHVTV--KIPAMITSHPNTTMARKGQTKELNCTA 818 Query: 759 VGNPRPTITWCKNN-------KPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENS 810 G I W + + P ++ GD T+ L P + D ++ A NS Sbjct: 819 RGEQPIIIRWERGDTVIDAERNPRYSITINKKGDEVISTLKLNPAERGDSVFFSCHAINS 878 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G +TV+EP + P L + ++ ++ ++ + R N + IT Y + Sbjct: 879 YGEGRGLIQLTVQEPPD---PPELEVREVKDRSM----NLRWIQRFDGNSI--ITSY-DI 928 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS------NSAGKSSHGARVTID 924 E + S++ + NI TN + I CV S N G+S +TI Sbjct: 929 EYKNKSDSWDHMYTTRNIS--PTNNQANIVELHPACVYSIRMYSYNKIGRSLPSKELTIS 986 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967 E+ VIL+ TS ++ W KKE+ Sbjct: 987 TEEAP---------PDGPPMDVILQPMTSQSIRVTWRAPKKEL 1020 Score = 37.5 bits (83), Expect = 4.0 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDD-DNVAT 567 P ++ T G + C V P +ITW + I P + + D +++ Sbjct: 599 PPLIQPFDIPSTSVGKLIYIACVVSSGDMPIRITWHKDGQPIVPGSASGVAIETKDFMSS 658 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 L I +V + G +TC+A N A S +LIV P Sbjct: 659 LQITKVTLKHNGNYTCIASNTAATVSWERQLIVTVP 694 >UniRef50_Q53EP0 Cluster: Fibronectin type III domain-containing protein 3B; n=32; Euteleostomi|Rep: Fibronectin type III domain-containing protein 3B - Homo sapiens (Human) Length = 1204 Score = 117 bits (282), Expect = 3e-24 Identities = 122/466 (26%), Positives = 197/466 (42%), Gaps = 36/466 (7%) Query: 1597 EGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS- 1654 EG P EVI Y + END ++ + +K LKRS K+ + ASNT G S Sbjct: 499 EGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSC 558 Query: 1655 --SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN-- 1710 V V D+P P P++ ++ +++W PP D+GG E+ KY +E + ++ Sbjct: 559 PSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEA 618 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 N+W +VA E Y L Y R + G S+ ES P ++T P Sbjct: 619 NQW-EVAYSGSATE-YTFTHLKPGTLYKLRACCISTGGHSQCSESLP--VRTLSIAPGQC 674 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS 1830 ++ V++ W G + +Y VE+ + + L Sbjct: 675 RPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLL 734 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 T Y+FR+ A N+ G PY+ +IT PP Q + +S + V + W P+ Sbjct: 735 PGTVYRFRVRALNDGGYG-PYSDVSEIT--TAAGPPGQCKAPCISCTPDGCVLVGWESPD 791 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 S+ G+ I+ Y +E+ + + +++ G I ++ + R+ A N G Sbjct: 792 SS-GADISEYRLEWG--EDEESLELIYHGTDTRFE-IRDLLPAAQYCCRLQAFNQAGAG- 846 Query: 1951 PTESQSVRLEKHATVPSPPTA-------PLEIRMVG-SNIVMTSWGTPEWDGGAPLLGYN 2002 S+ V + A+ P P + PL+ S ++ +W P + G+ +L Y Sbjct: 847 -PYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEP-CNNGSEILAYT 904 Query: 2003 IAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 I + D + T VG NT ++DL TY IRI A NEIG Sbjct: 905 IDLGDTSIT----VG----NTTMHVMKDLLPETTYRIRIQAINEIG 942 Score = 92.3 bits (219), Expect = 1e-16 Identities = 101/438 (23%), Positives = 175/438 (39%), Gaps = 18/438 (4%) Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEA--SNTAGTSSVEVTLKVYDKPSKPEGPV 1673 D +Y I + +K+L+ + + A ++ G+ S V+ + + P Sbjct: 326 DGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPP 385 Query: 1674 IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLN 1732 + S+ S+T++WK P+D+G ++T Y +E E N + + +C + KL Sbjct: 386 KLAHRSKSSLTLQWKAPIDNGS-KITNYLLEWDEGKRNSGFRQCFFGS--QKHCKLTKLC 442 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 Y FR+ A+N +G S S+ +V T ++P V + W E Sbjct: 443 PAMGYTFRLAARNDIGTSG--YSQEVVCYTLGNIPQMPSAPRLVRA-GITWVTLQWSKPE 499 Query: 1793 KNGGSPIIDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 +I Y +EI+++ + ++ L +T Y+FR+ A N G S P Sbjct: 500 GCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCP 559 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 T PP++P V TS ++KW P+ NGGS I Y++E + Sbjct: 560 SEVLVCTTSPDRPGPPTRP--LVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSE 617 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 + V GS E+ ++K R +T G S +ES VR A P Sbjct: 618 ANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIA--PGQCR 675 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRD 2030 P + V W P + G + Y++ + + + + EV L+ + + Sbjct: 676 PPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTE-PEDVASEV--YHGPELECTVGN 732 Query: 2031 LSENHTYMIRIYARNEIG 2048 L Y R+ A N+ G Sbjct: 733 LLPGTVYRFRVRALNDGG 750 Score = 53.6 bits (123), Expect = 6e-05 Identities = 32/138 (23%), Positives = 67/138 (48%), Gaps = 6/138 (4%) Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL-E 1391 P + + T+K ++ + ++L N G + +V + T D+P PP +P + Sbjct: 524 PKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGP 583 Query: 1392 IDSSSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWISVKNITKTQTSIQNLKTNSSY 1449 + S ++ WD P++ G S I+ Y++E + + +W + + T+ + +LK + Y Sbjct: 584 VTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLY 643 Query: 1450 RFRAYAVNEVDISDASET 1467 + RA ++ S SE+ Sbjct: 644 KLRACCISTGGHSQCSES 661 Score = 45.6 bits (103), Expect = 0.015 Identities = 29/113 (25%), Positives = 51/113 (45%), Gaps = 4/113 (3%) Query: 1358 YKLRLENNCGHADVEMNV---TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 ++L N+ G + V T+ + P P P ++ + + + W +PE +I Sbjct: 449 FRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVIT 508 Query: 1415 YVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASE 1466 Y +E QE + K + T +++NLK ++ Y+FR A N S SE Sbjct: 509 YTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSE 561 Score = 41.9 bits (94), Expect = 0.19 Identities = 50/221 (22%), Positives = 81/221 (36%), Gaps = 8/221 (3%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI-MREISRE 1681 T T++ +K+L + + I+A N G +K +P P P + + Sbjct: 913 TVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQ 972 Query: 1682 SVTIEWKPPLDDG-GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 S+ ++W E Y ++ E N R+I + TY +Q+L E Y FR Sbjct: 973 SLKLKWGDSNSKTHAAEDIVYTLQL-EDRNKRFISI--YRGPSHTYKVQRLTEFTCYSFR 1029 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII 1800 + A + G E SE T VP ++ S I W G P+ Sbjct: 1030 IQAASEAG--EGPFSETYTFSTTKSVPP-TIKAPRVTQLEGNSCEILWETVPSMKGDPVN 1086 Query: 1801 DYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 + ++K +I L NT Y+FR+ A Sbjct: 1087 YILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCA 1127 Score = 41.5 bits (93), Expect = 0.25 Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 9/163 (5%) Query: 1782 ESVYITWFPSE-KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 +S+ + W S K + I Y ++++ K++ ++Q+L+ T Y FRI Sbjct: 972 QSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQ 1031 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPP-SQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A +E G P++ + K++ P PR V++ S + W S G P+ N Sbjct: 1032 AASEAGEG-PFSETYTFSTTKSVPPTIKAPR---VTQLEGNSCEILWETVPSMKGDPV-N 1086 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISA 1942 YI++ + + ++ G I ++ + FR+ A Sbjct: 1087 YILQVLVGRESEYKQVYK--GEEATFQISGLQTNTDYRFRVCA 1127 >UniRef50_A7RGL5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 428 Score = 117 bits (281), Expect = 4e-24 Identities = 95/381 (24%), Positives = 168/381 (44%), Gaps = 22/381 (5%) Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 +ATL + ED +TCVA NA G SS+ EL V+ E T Sbjct: 1 IATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPI 60 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP--EPDIAWLFKGEEIVPDEN--- 679 + T S KP+ ++ +G + R + + EP++ L +++ P++ Sbjct: 61 GQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVI-DDVQPEDAGKY 119 Query: 680 --ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPP 735 I+ + ++ ++ + E V + E + P + + G E P Sbjct: 120 KCIAFNEKGEVEAEANLSIKEETETAPEKVEPTADVGVKEELTAPEFMDKERGPIEGHAP 179 Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITIL 792 ++I ++ M + +GE +++ +V G P P++ W K++KP+ + L +G+ ++ + Sbjct: 180 KLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQ 239 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEP-----TEENAEPPLFINRFQEITVKEK 847 K ++DE +YT A NS G +SA + V+E + E PP I EI V+E Sbjct: 240 K-AILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEG 298 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSE--TITQNFDGENIELVITNVDSEIDSGDYK 905 + RV +P P I WY+ I + I + + L+I N + DSG YK Sbjct: 299 EDARFDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTEL-TDSGKYK 357 Query: 906 CVASNSAGKSSHGARVTIDVE 926 VA+N G+ + +T+ E Sbjct: 358 VVATNEVGRETSRGELTVTEE 378 Score = 112 bits (269), Expect = 1e-22 Identities = 88/376 (23%), Positives = 162/376 (43%), Gaps = 32/376 (8%) Query: 494 KLPVFEKPT-SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 +L V EKP S +S P+ L P G + + +V G P+P++ WF+ +++ Sbjct: 33 ELQVDEKPEISAPESTTPVAETALI---VPIGQEAKLDARVTGSPKPEVEWFKDGKVVED 89 Query: 553 SQDFQMYYDDDN--VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSE 610 + F +Y +D+ V +LVI +V PEDAG + C+A N G + L ++ + Sbjct: 90 AGRF-LYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANLSIKEETETAPEK 148 Query: 611 MTVXXXXXXXXXXXXADI-------LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP 663 + + +EG P + + + EG D ++ C + PEP Sbjct: 149 VEPTADVGVKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEP 208 Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG----EA 719 + WL + + D+ ++ ++ + LK+ E YT A N G A Sbjct: 209 SVEWLKDDKPLPRDQRLTPMYNGEV----ATLKLQKAILEDEALYTCTASNSLGSVSSSA 264 Query: 720 SLPI----VLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 L + V+ I PP +I PL + V++GE +V G+P+P I W K + Sbjct: 265 ELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPEIQWYKGTTEI 324 Query: 776 -----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 + +++ + +S+ I+ ++ D G Y + A N G + +TV E + + Sbjct: 325 FDEDRFEIVEEAEDNLYSLIIVN-TELTDSGKYKVVATNEVGRETSRGELTVTEELQNSR 383 Query: 831 EPPLFINRFQEITVKE 846 +F +T+++ Sbjct: 384 IKMVFDGETCSLTIRD 399 Score = 80.6 bits (190), Expect = 4e-13 Identities = 85/323 (26%), Positives = 137/323 (42%), Gaps = 50/323 (15%) Query: 705 EGTYTVVAVNREGEASLPIVLKI-KTGEKEPPQVIEPLK--SMIVRQGESVILSAQVVGN 761 E YT VA N G S L++ + E P+ P+ ++IV G+ L A+V G+ Sbjct: 14 EALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARVTGS 73 Query: 762 PRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 P+P + W K+ K V + L + + ++ + +D G Y A N +G E Sbjct: 74 PKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAE 133 Query: 818 AVITVEEPTE---ENAEPPLFINRFQEITV-----KEKGTI-----KLVAR--------- 855 A ++++E TE E EP + +E+T KE+G I KL+A Sbjct: 134 ANLSIKEETETAPEKVEPTADVGVKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEG 193 Query: 856 --------VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 VT P PS+ W ++++ + + +T ++GE L + E D Y C Sbjct: 194 EDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILE-DEALYTCT 252 Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKS----------YETEEGKTVILECQT--SHT 955 ASNS G S A + +D + V + S E +EG+ + + S Sbjct: 253 ASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQ 312 Query: 956 VSTKWYHNKKEISGMDHREIIQE 978 +WY EI D EI++E Sbjct: 313 PEIQWYKGTTEIFDEDRFEIVEE 335 Score = 77.0 bits (181), Expect = 5e-12 Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 23/231 (9%) Query: 488 LNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 + E++ +K + AP + ++RP +G C+V G P P + W + Sbjct: 157 VKEELTAPEFMDKERGPIEGHAPKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDD 216 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 + Q Y+ + VATL +++ ED +TC A N+ G SS+ EL V D Sbjct: 217 KPLPRDQRLTPMYNGE-VATLKLQKAILEDEALYTCTASNSLGSVSSSAELQV-----DE 270 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIA 666 + + E + P P + V EG D + R+ P+P+I Sbjct: 271 KGVVPISP--------------EPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPEIQ 316 Query: 667 WLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 W EI ++ + E++ ++Y L I N + G Y VVA N G Sbjct: 317 WYKGTTEIFDEDRFEIVEEAEDNLYS--LIIVNTELTDSGKYKVVATNEVG 365 Score = 64.9 bits (151), Expect = 2e-08 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 3/139 (2%) Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K ++DE +YT A N+ G +SA + V+E E +A + V KL Sbjct: 7 KSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKL 66 Query: 853 VARVTRNPVPSITWYRNNEIISPSETI--TQNFDGENIELVITNVDSEIDSGDYKCVASN 910 ARVT +P P + W+++ +++ + ++ + E LVI +V E D+G YKC+A N Sbjct: 67 DARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPE-DAGKYKCIAFN 125 Query: 911 SAGKSSHGARVTIDVEKVT 929 G+ A ++I E T Sbjct: 126 EKGEVEAEANLSIKEETET 144 Score = 59.7 bits (138), Expect = 9e-07 Identities = 46/182 (25%), Positives = 79/182 (43%), Gaps = 18/182 (9%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL-KTAKAT--YENR-XXXXXXXXXXXXXXXYKCIA 1552 ED +TC G P+P V W +D K L + + T Y Y C A Sbjct: 194 EDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTA 253 Query: 1553 FNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV----------GDEWLVTAVIEGIPPP 1602 N G V +S + + +K V+ IS E + + G++ ++G P P Sbjct: 254 SNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQP 313 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAG--TSSVEV 1658 E+ WYK ++ ++ + I + + ++ + I + + S KY + A+N G TS E+ Sbjct: 314 EIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATNEVGRETSRGEL 373 Query: 1659 TL 1660 T+ Sbjct: 374 TV 375 Score = 55.2 bits (127), Expect = 2e-05 Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 6/144 (4%) Query: 474 LMDENNYTQYLQKKLNEKID--KLPVFEK---PTSEEQSMAPIFVEKLRPKHTPDGSTVQ 528 L DE YT L +L V EK P S E P + L +G + Sbjct: 243 LEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDAR 302 Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGTFTCVAKN 587 F+ +V+G P+P+I W++ T I F++ + +DN+ +L+I D+G + VA N Sbjct: 303 FDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATN 362 Query: 588 AAGFASSTTELIVEAPLSDHGSEM 611 G +S EL V L + +M Sbjct: 363 EVGRETSRGELTVTEELQNSRIKM 386 Score = 53.6 bits (123), Expect = 6e-05 Identities = 51/210 (24%), Positives = 96/210 (45%), Gaps = 26/210 (12%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P+ I +++ ++ E + A++ E+ + V W +D + + P+ + G + L Sbjct: 179 PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPL-PRDQRLTPMYNGEVATLK 237 Query: 1076 IRNTSVHDEGEYSCI----LRDESCTAEVTVVEL-----------PPEIITRLQNQKVNK 1120 ++ + DE Y+C L S +AE+ V E PP+IIT L +V + Sbjct: 238 LQKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQE 297 Query: 1121 GNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEY 1176 G A F++ + KG ++W+K +EI + ++ + + L I + +L D+G+Y Sbjct: 298 GEDARFDVRV-KGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKY 356 Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRL 1202 EVG LTV E N +++ Sbjct: 357 KVVATNEVGRETSRGELTVTEELQNSRIKM 386 Score = 50.0 bits (114), Expect = 7e-04 Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITI--SNEDIKQKH---KVGDEWLVTAVIEGIPPP 1602 Y C+A N G V +S + + +KP I+ S + + +G E + A + G P P Sbjct: 17 YTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARVTGSPKP 76 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSV--IRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 EV W+K+G +E+ + E+ V + I +++ + KY A N G E L Sbjct: 77 EVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEVEAEANL 136 Query: 1661 KVYDK 1665 + ++ Sbjct: 137 SIKEE 141 Score = 46.8 bits (106), Expect = 0.007 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 16/184 (8%) Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-- 1269 DA +T E+ + V W K + ++ T + + + TL ++K +D+ YTC Sbjct: 195 DAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCTAS 254 Query: 1270 --LLDAKSTTKLKVE---VVEF------PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 L S+ +L+V+ VV PP I+ E ++ G D V + PQP Sbjct: 255 NSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEGEDARFDVRVKGSPQPE 314 Query: 1319 DEWIV-NSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 +W ++I + + + SL I E TD+G YK+ N G +T Sbjct: 315 IQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKVVATNEVGRETSRGELT 374 Query: 1377 ILDK 1380 + ++ Sbjct: 375 VTEE 378 Score = 46.0 bits (104), Expect = 0.011 Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 20/199 (10%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P++I ++ ++ +G A E+T K + V W KD + + +G+ LK+ Sbjct: 179 PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKL 238 Query: 1166 YDCDLDDAGEYSCEVGNS----KCTAILTVEE----PSINFTLRLPEFIL------VPAN 1211 L+D Y+C NS +A L V+E P + P+ I V Sbjct: 239 QKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISPEPVSPPDIITPLGEIEVQEG 298 Query: 1212 TDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTC 1268 DA V + ++ WYK + I D ++F ++ + + +LII D +Y Sbjct: 299 EDARFDVRVKGSPQPEIQWYKGTTEIFDEDRFEIVEEAEDNLYSLIIVNTELTDSGKYKV 358 Query: 1269 VLLD--AKSTTKLKVEVVE 1285 V + + T++ ++ V E Sbjct: 359 VATNEVGRETSRGELTVTE 377 Score = 44.0 bits (99), Expect = 0.046 Identities = 36/139 (25%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR-------GS 1303 TL + T +D+ YTCV +A + E+ V+ P+I E + G Sbjct: 3 TLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQ 62 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA--SLTIKKVENTDAGIYKLR 1361 + L P+P EW + K+++ D + SL I V+ DAG YK Sbjct: 63 EAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCI 122 Query: 1362 LENNCGHADVEMNVTILDK 1380 N G + E N++I ++ Sbjct: 123 AFNEKGEVEAEANLSIKEE 141 Score = 44.0 bits (99), Expect = 0.046 Identities = 22/100 (22%), Positives = 44/100 (44%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 PK++ R +I G D + + P+P+ EW+ + K + + + P + + A+L + Sbjct: 179 PKLIAEMRPMQIIEGEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKL 238 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 +K D +Y N+ G + + +K P P Sbjct: 239 QKAILEDEALYTCTASNSLGSVSSSAELQVDEKGVVPISP 278 Score = 42.7 bits (96), Expect = 0.11 Identities = 22/86 (25%), Positives = 41/86 (47%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G++ ++T + G P P V W K+ L D+ + + +++++ + YT Sbjct: 193 GEDAVMTCEVTGKPEPSVEWLKDDKPLPRDQRLTPMYNGEVATLKLQKAILEDEALYTCT 252 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ASN+ G+ S L+V +K P P Sbjct: 253 ASNSLGSVSSSAELQVDEKGVVPISP 278 Score = 41.5 bits (93), Expect = 0.25 Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 13/127 (10%) Query: 1071 IRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELP----PEIITRLQNQK--VNK 1120 I L ++ ++ DE Y+C+ L S +AE+ V E P PE T + V Sbjct: 1 IATLTFKSATLEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPI 60 Query: 1121 GNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQ--KLKIYDCDLDDAGEYS 1177 G +A + +T V WFKDG ++ + D + + L I D +DAG+Y Sbjct: 61 GQEAKLDARVTGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYK 120 Query: 1178 CEVGNSK 1184 C N K Sbjct: 121 CIAFNEK 127 Score = 37.9 bits (84), Expect = 3.0 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 12/126 (9%) Query: 1170 LDDAGEYSC----EVGNSKCTAILTVEE-PSINF---TLRLPEF-ILVPANTDAYLTVEI 1220 L+D Y+C +G+ +A L V+E P I+ T + E ++VP +A L + Sbjct: 11 LEDEALYTCVATNALGSVSSSAELQVDEKPEISAPESTTPVAETALIVPIGQEAKLDARV 70 Query: 1221 PDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--TLIIRKCTEDDQCEYTCVLLDAKSTT 1277 +V W+K V+ED +F + D + +L+I +D +Y C+ + K Sbjct: 71 TGSPKPEVEWFKDGKVVEDAGRFLYVEDEEPEVFSLVIDDVQPEDAGKYKCIAFNEKGEV 130 Query: 1278 KLKVEV 1283 + + + Sbjct: 131 EAEANL 136 >UniRef50_A7RNP0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1874 Score = 116 bits (280), Expect = 5e-24 Identities = 182/877 (20%), Positives = 326/877 (37%), Gaps = 73/877 (8%) Query: 1224 TLDVTWYKKK-SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL------------ 1270 T ++TW+K + ++ + + +++SD +K L I E D +Y+CV Sbjct: 130 TPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLRESDNGKYSCVARNALGMVFSSQA 187 Query: 1271 LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + A+ L + VV P+ ++ + +DV L + P P+ W V+ Sbjct: 188 MPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGS---- 243 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 I ++ L I+ ++ + G Y ++N G VT+ P P +PN Sbjct: 244 ------RISGQNGELIIRGIQRS--GNYSCIADSNMGRVQAYAYVTVRLLPFAPSRPNAA 295 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSY 1449 I S +I I W P G + Y V+Y+ TEW + N+ Q+ + L+ SSY Sbjct: 296 SITSDAIKITW-HPR--GAHVVTSYEVQYRLKGKTEWQEITNVRGMQSLVVSGLRPFSSY 352 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSP--TVEKPLKNITTEPNEDIELTCIFGG 1507 FR +AVN + S S EY ETK S +E + T+ + G Sbjct: 353 EFRVFAVNSLGRSRPSLMAEY--TTSETKPGSAPRNIEAMGVSDTSFKAGWLPPISANGR 410 Query: 1508 VPQPKVTWYRD-GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVG 1566 + ++ + D + + + + ++ +A+N G+ S VV Sbjct: 411 IRGYRLYYSLDLLEDISQWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVA 470 Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNITTKE 1625 ++ + + ++ VT P + Y NK + D + + Sbjct: 471 VKTQKGVPGQPRSVQLSVLSSTAIRVTWSPPRYPGDGIFGYDVYYNKSKQDMD-TVIGAF 529 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP-EGPVIMREISRESVT 1684 + + I L K + A + G + L +P + P ++ SR+S T Sbjct: 530 QMNTKEIMGLTPYTVYKVAVAAKSDKGVGPMSFVLTARTDEDRPSDAPQNIQGRSRDSTT 589 Query: 1685 IE--WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 +E W PP + L + K+ R K VD + + L++ Y V Sbjct: 590 LEISWDPPRPEHRNGLITHFTIKYRAKGQRGAKYLTVDATKTSVVLHNLDKFTNYFIWVQ 649 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 A G + S+ + TA DVP+ ++ ++ + W P I+ Y Sbjct: 650 ASTKQG--DGPFSDKHTVSTAEDVPNGAPRDVRIRVHNSTTMTVKWNPPTTKQDGKILGY 707 Query: 1803 KV---EIKQEGKKW--------KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPY 1851 V + +G + K + L+ TTYQ + A G Sbjct: 708 MVFYTRVDDQGNQLRPPAQPESKDSMSEENHKVHLTGLAPETTYQIEVAAYTIKGDGARS 767 Query: 1852 TSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS 1911 + T+ ++ PP + S VTL W + Y + ++G+ Sbjct: 768 VTRLAKTMAQSPDPPFVYLERASGDPIS-DVTLAWRTSATGVIEYKVRYAKSVRRLRGRD 826 Query: 1912 W----TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 K + + +++ +F +S G S P S+ + + P Sbjct: 827 QGNLKMKEIKFKSHTTKQKFQSLANGIWYLFNVSLRTKAGWS-PETSRWIEIP-----PG 880 Query: 1968 PPTA-PLEIR--MVGSNIVMTSWGTPE-WDGGAPLLGYNIAIRDVTKTMWMEVGKV-DVN 2022 PP+ PL +R V S V +W P+ W+ G P+LGY++ K + V V N Sbjct: 881 PPSGPPLNVRAVAVSSTSVEVTWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVTSPN 940 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 K ++ L + Y +R+ A +G+ + EPF Sbjct: 941 IFKVVLKRLKKFREYEVRVRAIGMLGMG---PASEPF 974 Score = 71.7 bits (168), Expect = 2e-10 Identities = 77/303 (25%), Positives = 124/303 (40%), Gaps = 34/303 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT + PK + + C + P P + W +K ++ + I + Y Sbjct: 1 PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTW-YKNGSVIRNSRIQIFTMP----YGG 55 Query: 694 VLKITNVK-KFQEGTYTVVAVNREG----EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 +++I ++ K + TY A N G ++S IV T P++ + R Sbjct: 56 LIRIGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRS 115 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGVYT 804 G+ V + VG P P ITW K+ P+ + SDG IT L+ D G Y+ Sbjct: 116 GDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRKLRITDLRE---SDNGKYS 172 Query: 805 LKAENSEGIAETS----AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 A N+ G+ +S A + + P F R Q+ TV ++L +P Sbjct: 173 CVARNALGMVFSSQAMPARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSP 232 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 PSI W + IS G+N EL+I + SG+Y C+A ++ G+ A Sbjct: 233 TPSIVWEVDGSRIS----------GQNGELIIRGIQR---SGNYSCIADSNMGRVQAYAY 279 Query: 921 VTI 923 VT+ Sbjct: 280 VTV 282 Score = 49.6 bits (113), Expect = 0.001 Identities = 77/342 (22%), Positives = 130/342 (38%), Gaps = 55/342 (16%) Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPS--ETITQNFDGENIELVITNVDSEIDSGDY 904 +G + ++ VT +P+P++TWY+N +I S + T + G + I + ++I Y Sbjct: 15 RGFVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGG---LIRIGPLRAKIHKATY 71 Query: 905 KCVASNSAGKSSHGARV----TIDVEKVTF---VKHLQKSYETEEGKTVILECQT--SHT 955 +C A N G + T + F KH + G V C + T Sbjct: 72 ECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKH-PSFKQRRSGDDVTFTCAAVGTPT 130 Query: 956 VSTKWYHNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD--------QET 1006 + W+ ++ I D R ++ +GR D G C+ ++ Q Sbjct: 131 PNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDNGKYSCVARNALGMVFSSQAM 188 Query: 1007 STMLVVKETI------PEFIRKLQDFEV-KEKDVAILEVEINSETADVVWERDGEIIKPK 1059 L + T+ PEF + QD V + DV + S T +VWE DG I Sbjct: 189 PARLFIYLTLSVVRSKPEFTLRPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRIS-- 246 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVN 1119 G +L IR + G YSCI + + V+ + RL + Sbjct: 247 ---------GQNGELIIR--GIQRSGNYSCI-----ADSNMGRVQAYAYVTVRLLPFAPS 290 Query: 1120 KGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQ 1161 + N A+ + K + W G+ + S +Q + GK + Sbjct: 291 RPNAASITSDAIK----ITWHPRGAHVVTSYEVQYRLKGKTE 328 Score = 48.4 bits (110), Expect = 0.002 Identities = 42/156 (26%), Positives = 60/156 (38%), Gaps = 21/156 (13%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 K G V F C G P P ITWF+ I + D L I ++ D Sbjct: 111 KQRRSGDDVTFTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGR--KLRITDLRESDN 168 Query: 579 GTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSK 638 G ++CVA+NA G S+ + A L + + V P F+ Sbjct: 169 GKYSCVARNALGMVFSSQAM--PARLFIYLTLSVVRS-----------------KPEFTL 209 Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 +P+ + VD +D+ L+C P P I W G I Sbjct: 210 RPQDKTVDPDTDVELKCSARGSPTPSIVWEVDGSRI 245 Score = 47.6 bits (108), Expect = 0.004 Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 13/182 (7%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX- 1540 PTV K+ + + C G P P +TWY++G ++ ++ Sbjct: 1 PTVTLTPKDFAGVTRGFVYMICNVTGSPMPTLTWYKNGSVIRNSRIQIFTMPYGGLIRIG 60 Query: 1541 ---XXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPV--ITISNEDIKQKHKVGDEWL 1591 Y+C A N G + T V KP I+ ++ + GD+ Sbjct: 61 PLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAGFPRIAKHPSFKQRRSGDDVT 120 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 T G P P + W+K+ + ND ++ + + +RI +L+ S + KY+ A N Sbjct: 121 FTCAAVGTPTPNITWFKDRLPIVLNDPRVSVLSDGRK--LRITDLRESDNGKYSCVARNA 178 Query: 1651 AG 1652 G Sbjct: 179 LG 180 Score = 47.6 bits (108), Expect = 0.004 Identities = 54/227 (23%), Positives = 91/227 (40%), Gaps = 18/227 (7%) Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 + Q L+ Y F + R + G S + +I G PP R VS S SV + Sbjct: 845 KFQSLANGIWYLFNVSLRTKAGWSPETSRWIEIPPGPPSGPPLNVRAVAVS---STSVEV 901 Query: 1885 KWTEPES-NGGSPITNYIIEFKTV--KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 W+ P+ N G PI Y + + +G K VT ++ + ++ +K+ E R+ Sbjct: 902 TWSAPDIWNRGGPILGYSVMYNPANKRGDVTVKNVT-SPNIFKVVLKRLKKFREYEVRVR 960 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 A +G+ +E R ++ P R VGS+ V+ W P D G Sbjct: 961 AIGMLGMGPASEPFIDRTKEDGKCHCRDVRP---RTVGSDWVILEWLPPRIDAGID---- 1013 Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 +T + V + + F ++ L + Y +R+ A N +G Sbjct: 1014 ----TPLTHADEVRVDALTADVQTFKVQGLVPHMKYTVRLSASNAMG 1056 Score = 44.0 bits (99), Expect = 0.046 Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 5/103 (4%) Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P +T++ +D + G +++ V G P P + WYKNG+ + N + I T +I Sbjct: 1 PTVTLTPKDFAGVTR-GFVYMICNVT-GSPMPTLTWYKNGSVIRNSR-IQIFTMPYGGLI 57 Query: 1631 RIKELK-RSHSSKYTIEASNTAGTSSVE-VTLKVYDKPSKPEG 1671 RI L+ + H + Y EA N G + TL V+ +KP G Sbjct: 58 RIGPLRAKIHKATYECEADNGVGPPLRDSSTLIVHTASTKPAG 100 >UniRef50_Q94155 Cluster: Unc-40 protein; n=2; Caenorhabditis|Rep: Unc-40 protein - Caenorhabditis elegans Length = 1415 Score = 115 bits (277), Expect = 1e-23 Identities = 135/605 (22%), Positives = 230/605 (38%), Gaps = 51/605 (8%) Query: 1479 IQSPTVEKPLKNITT------EPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE 1530 + + TV L ITT E ++ L C+ + +P+V W +D +++ + Sbjct: 236 VTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVDGVRIRRV 295 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEW 1590 Y C A N+ ++ + V ++ P IT + K + D Sbjct: 296 GVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRAPPRIT-TRPTTKVAVETADVE 354 Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 L P V WYKNG + EY + + +RI + R+ + Y A N Sbjct: 355 LECGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNR---LRILGVVRADQAIYQCIAEND 410 Query: 1651 AGT--SSVEVTLKVYDK---------PSKPEGPVIMREISRES--VTIEWKPPLDDGGLE 1697 G+ +S ++ + D P P+ +R S S + +EW PP+ G Sbjct: 411 VGSEQASAQLLVDAPDSSSVAASSGVPMTSSAPLGLRSTSSGSRFINVEWDPPVQRNG-N 469 Query: 1698 LTKYAI--EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALES 1755 + +Y I + + D R I + + + L + Y+ RV A+N G + +S Sbjct: 470 IMRYHIFYKDNLIDRERMINSSST-----SATLTSLQPSTMYLIRVTAENEAGMGKFSDS 524 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKK 1812 + VP E++ I W P +GG P + YK+ E + Sbjct: 525 LKVTTNKEQAVPGKVASLTTTAT-GPETIDIRWSP--PSGGQPALRYKIFYSHDPLEKNE 581 Query: 1813 WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR-N 1871 + + + T YQ RI A G+ L S D + + PS P N Sbjct: 582 KETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGL---SSDTVKVRTQSDEPSAPPVN 638 Query: 1872 FVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENI 1930 +S SV + W EPE IT Y +++KT + + + + E+ + N+ Sbjct: 639 IQAEADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYTMGNL 698 Query: 1931 KEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMTSWGT 1989 + + + R++ N G ++ S+ AP EIR G + ++ SW Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAPREIRPHAGIDYILVSW-L 757 Query: 1990 PEWDGGAPLLGYNIAI-RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 P D + GY I V T E +V +T ++ I L Y+I + A N +G Sbjct: 758 PPADEQNLVRGYQIGWGLSVPDT---ETIRVTASTTQYKIARLHSERDYVISLRAFNNLG 814 Query: 2049 LSEPL 2053 P+ Sbjct: 815 SGFPI 819 Score = 70.1 bits (164), Expect = 6e-10 Identities = 62/281 (22%), Positives = 107/281 (38%), Gaps = 21/281 (7%) Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 +G C + + P P WL E IV + S+ L+I++ + EG Sbjct: 161 KGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSN------TLEISSTQSRHEG 214 Query: 707 TYTVV---AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 TY A R + + + +T E + P + +V QG+ +L V R Sbjct: 215 TYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTP-RLQVVEQGDEFLLECLVASLIR 273 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P + W K+++ + + S ++ ++D G+YT +A N++ + + + V Sbjct: 274 PQVRWLKDSRQIIVDGVRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRAVSVEVR 333 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 P P ++ V+ P + WY+N E I SE F Sbjct: 334 APPRITTRPT------TKVAVETADVELECGTAAARPEARVNWYKNGEAIIGSE----YF 383 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 E L I V D Y+C+A N G A++ +D Sbjct: 384 VIEPNRLRILGV-VRADQAIYQCIAENDVGSEQASAQLLVD 423 Score = 54.0 bits (124), Expect = 4e-05 Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 13/191 (6%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F P+ Q V++G + LLEC + ++ P + WL +I+ D V I + S + Sbjct: 247 FITTPRLQVVEQGDEFLLECLVASLIRPQVRWLKDSRQIIVD---GVRIR---RVGVSSI 300 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVIL 754 ++ G YT A N + + ++++ PP++ P + V + + Sbjct: 301 LVSRASIEDTGLYTCRASNNDDSIDRAVSVEVRA----PPRITTRPTTKVAVETADVELE 356 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 P + W KN + + + + + IL + D+ +Y AEN G Sbjct: 357 CGTAAARPEARVNWYKNGEAIIG-SEYFVIEPNRLRILGVVRA-DQAIYQCIAENDVGSE 414 Query: 815 ETSAVITVEEP 825 + SA + V+ P Sbjct: 415 QASAQLLVDAP 425 Score = 37.1 bits (82), Expect = 5.3 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 9/109 (8%) Query: 1358 YKLRLE----NNCGHADVEMNV-TILDKPSPPGKPNILEIDSS-SINICWDEPENTG-NS 1410 Y++R+E N G + + V T D+PS P E DSS S+ + WDEPE N Sbjct: 604 YQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQAEADSSTSVRVSWDEPEEESVNG 663 Query: 1411 TIIYYVVEY--QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 I Y ++Y + V + T + ++ NL+ N+ Y R VN Sbjct: 664 EITGYRLKYKTKARGAKGNTLVIDATAREYTMGNLEPNTQYLIRMAVVN 712 >UniRef50_Q9Y2H6 Cluster: Fibronectin type-III domain-containing protein 3a; n=37; Euteleostomi|Rep: Fibronectin type-III domain-containing protein 3a - Homo sapiens (Human) Length = 1134 Score = 115 bits (277), Expect = 1e-23 Identities = 115/430 (26%), Positives = 181/430 (42%), Gaps = 34/430 (7%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMREISRESVTIEWK 1688 +K L+RS K+ + A N+ G S+ ++ DKP P P + +I S I W Sbjct: 463 VKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWD 522 Query: 1689 PPLDDGGLELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 PP D+GG + KY +E E N N+W + + +LN C Y RV + Sbjct: 523 PPKDNGGATINKYVVEMAEGSNGNKWEMI--YSGATREHLCDRLNPGCFYRLRVYCISDG 580 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G ++ SE ++++T P + + + W P +GGSPI Y VE+ Sbjct: 581 G--QSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMS 638 Query: 1808 Q-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 E + + + L TY FR+ A N++G P++ +K I PP Sbjct: 639 PIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFG-PFS--EKCDITTAPGPP 695 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 Q + V+ ++ + W P SN G+ +T Y +E+ V+G +I G + + Sbjct: 696 DQCKPPQVTCRSATCAQVNWEVPLSN-GTDVTEYRLEWGGVEGS--MQICYCGPGL-SYE 751 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI--------RMV 1978 I+ + R+ A + VG S+ V +VP T EI Sbjct: 752 IKGLSPATTYYCRVQALSVVGAG--PFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYS 809 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 S + SW P D G+ +L Y+I D + VGKV + I +L + TY Sbjct: 810 PSTCLAISWEKP-CDHGSEILAYSIDFGDKQS---LTVGKV----TSYIINNLQPDTTYR 861 Query: 2039 IRIYARNEIG 2048 IRI A N +G Sbjct: 862 IRIQALNSLG 871 Score = 108 bits (260), Expect = 1e-21 Identities = 104/428 (24%), Positives = 172/428 (40%), Gaps = 30/428 (7%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREISRESVTIEW 1687 +I +L + K+ + A N GTS + Y PS P PV+ + ++++W Sbjct: 365 KITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKA-GITWLSLQW 423 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 P E Y +E E + K D+ Y ++ L + +Y F+VIA N Sbjct: 424 SKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDL-AYTVKNLRRSTKYKFKVIAYNSE 482 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G S SE + T D P I + S ITW P + NGG+ I Y VE+ Sbjct: 483 GKSN--PSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMA 540 Query: 1808 Q--EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 + G KW+ +L+ Y+ R+Y ++ G S + + + P Sbjct: 541 EGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQS---AVSESLLVQTPAVP 597 Query: 1866 PS---QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P PR + ++ + L+W P +GGSPI+ Y +E ++ K + V G V Sbjct: 598 PGPCLPPR--LQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIE-KDEPREVYQGSEV 654 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP--TAPLEIRMVGS 1980 E + ++ FR+ A N +G +E + T P PP P ++ + Sbjct: 655 -ECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDI-----TTAPGPPDQCKPPQVTCRSA 708 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 +W P G + Y + V + M++ L + I+ LS TY R Sbjct: 709 TCAQVNWEVP-LSNGTDVTEYRLEWGGVEGS--MQICYCGPG-LSYEIKGLSPATTYYCR 764 Query: 2041 IYARNEIG 2048 + A + +G Sbjct: 765 VQALSVVG 772 Score = 99.1 bits (236), Expect = 1e-18 Identities = 111/462 (24%), Positives = 193/462 (41%), Gaps = 32/462 (6%) Query: 1614 ENDKEYNITTKEKTSVIRIKELKRS--HSSKYTIEASNTAGT-SSVEVTLKVYDKPSKPE 1670 ++ K ++ E+T+ I + +LK + + +K E ++ GT S E+ + +P P Sbjct: 253 KDGKYKSVYVGEETN-ITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPN 311 Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQK 1730 P I ++ S+T++WK P D+G ++ + +E E N + + + I K Sbjct: 312 PPRIANR-TKNSLTLQWKAPSDNGS-KIQNFVLEWDEGKGNGEFCQCYMGSQ-KQFKITK 368 Query: 1731 LNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 L+ FR+ A+N G S SE ++ T+ PS ITW Sbjct: 369 LSPAMGCKFRLSARNDYGTSGF--SEEVLYYTSGCAPSMPASPVLT------KAGITWLS 420 Query: 1791 SE--KNGGSPI---IDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 + K G+P I Y +E+++E G +K ++ L +T Y+F++ A N Sbjct: 421 LQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYN 480 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 G S P + T P +P V + S S + W P+ NGG+ I Y++E Sbjct: 481 SEGKSNPSEVVEFTTCPDKPGIPVKPS--VKGKIHSHSFKITWDPPKDNGGATINKYVVE 538 Query: 1904 F-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 + G W I + G+ EH + + R+ + G S S+S+ ++ Sbjct: 539 MAEGSNGNKWEMIYS--GATREHLCDRLNPGCFYRLRVYCISDGGQS--AVSESLLVQTP 594 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 A P P P + + WG P DGG+P+ Y++ + + K EV + Sbjct: 595 AVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREV--YQGS 652 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064 ++ + L TY R+ A N++G P PG Sbjct: 653 EVECTVSSLLPGKTYSFRLRAANKMGFG-PFSEKCDITTAPG 693 Score = 65.3 bits (152), Expect = 2e-08 Identities = 68/286 (23%), Positives = 109/286 (38%), Gaps = 19/286 (6%) Query: 1779 IDNESVYITWFPSEK--NGGSP------IIDYKVEIKQEGK--KWKXXXXXXXXXARIQK 1828 I +V +TW P NG + + Y+V I GK K+K + Sbjct: 213 IQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLND 272 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE 1888 L Y ++ A P ++ T+ P+ PR ++ T S+TL+W Sbjct: 273 LKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPR---IANRTKNSLTLQWKA 329 Query: 1889 PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 P N GS I N+++E+ KG GS + I + FR+SA N G Sbjct: 330 PSDN-GSKIQNFVLEWDEGKGNG-EFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGT 387 Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 S S+ V PS P +P+ + G + W P + Y + + + Sbjct: 388 S--GFSEEVLYYTSGCAPSMPASPV-LTKAGITWLSLQWSKPSGTPSDEGISYILEMEEE 444 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 T + K D L + +++L + Y ++ A N G S P E Sbjct: 445 TSGYGFK-PKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSE 489 Score = 59.7 bits (138), Expect = 9e-07 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 5/138 (3%) Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNIL- 1390 KP D + + T+K + + +K+ N+ G + +V T DKP P KP++ Sbjct: 451 KPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKG 510 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSY 1449 +I S S I WD P++ G +TI YVVE E + +W + + + L Y Sbjct: 511 KIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFY 570 Query: 1450 RFRAYAVNEVDISDASET 1467 R R Y +++ S SE+ Sbjct: 571 RLRVYCISDGGQSAVSES 588 Score = 41.1 bits (92), Expect = 0.33 Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK-NITKTQTS 1439 PS P P + + + +++ W +P T + I Y++E +E + K + + Sbjct: 403 PSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYT 462 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 ++NL+ ++ Y+F+ A N S+ SE E+ Sbjct: 463 VKNLRRSTKYKFKVIAYNSEGKSNPSEVVEF 493 Score = 36.3 bits (80), Expect = 9.2 Identities = 48/227 (21%), Positives = 90/227 (39%), Gaps = 24/227 (10%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV-------- 1683 IK L + + ++A + G + PS P ++EIS + + Sbjct: 752 IKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPS 811 Query: 1684 ---TIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFR 1740 I W+ P D G E+ Y+I+ + + KV +Y I L + Y R Sbjct: 812 TCLAISWEKPCDHGS-EILAYSIDFGDKQSLTVGKVT-------SYIINNLQPDTTYRIR 863 Query: 1741 VIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPI 1799 + A N +G S I +KT P ++++ + W + K + Sbjct: 864 IQALNSLGAGPF--SHMIKLKTKPLPPDPPRLECVA--FSHQNLKLKWGEGTPKTLSTDS 919 Query: 1800 IDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 I Y ++++ + ++ ++Q+L+ +T+Y+F I A NE G Sbjct: 920 IQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAG 966 >UniRef50_UPI0000F1ECB5 Cluster: PREDICTED: similar to novel hemicentin protein; n=1; Danio rerio|Rep: PREDICTED: similar to novel hemicentin protein - Danio rerio Length = 841 Score = 115 bits (276), Expect = 2e-23 Identities = 102/425 (24%), Positives = 169/425 (39%), Gaps = 35/425 (8%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 T+Q V G P PQ+ WF+ + + + + +D LVI +G F CV Sbjct: 252 TIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGVSLAEDGA--LVIGSASASHSGDFKCV 309 Query: 585 AKNAAGFASSTTEL-IVEAP----------------LSDHGSEMTVXXXXXXXXXXXXAD 627 A N AG T L ++E P DH + Sbjct: 310 ATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYT 369 Query: 628 ILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 I PP S Q V G ++ ++CR+ P P + W GE + P+ + V Sbjct: 370 IEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFL 429 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 VL++ +V+ G Y VA N G + L I+ + +++ Sbjct: 430 EKGQ----VLRVKSVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVV 485 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 + G +L +V G P PTITW K+N+P+ + P + + + +D G YT Sbjct: 486 L--GFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQGGQSLRVAAARGEDAGAYTC 543 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A N G A + + P + + + +E V+ GT+ L P P Sbjct: 544 RATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEPVTQ 603 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDS--GDYKCVASNSAGKSSHGARVTI 923 W+++ ++++ + G ++ + +VD+ + S G Y CV SNSAG+ +TI Sbjct: 604 WFKDGQLLNGN-----THSGLSVNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHLTI 658 Query: 924 DVEKV 928 V V Sbjct: 659 QVPPV 663 Score = 87.8 bits (208), Expect = 3e-15 Identities = 131/574 (22%), Positives = 231/574 (40%), Gaps = 69/574 (12%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS+++L C + P P + W G+ I P + S LKI++V+ Sbjct: 104 GSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPS------GSLKISDVRVVDSKL 157 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 YT AVN G SL L+++ + P LK++I G++V+L V G P P ++ Sbjct: 158 YTCSAVNPAGNVSLTYNLQVQAKPRIHP-APSTLKALI---GQTVVLPCVVQGEPSPQVS 213 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV---EE 824 W N LP SD + ++ + D G Y A NS G V+ V Sbjct: 214 WLHN-----GLPVASD----RMLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPA 264 Query: 825 PTEENAEPPLFINRFQE---ITVKEKGTIKLVAR----------VTRNPVPSITWYRNNE 871 P + L ++ + +++ E G + + + V N S+ + Sbjct: 265 PQVRWFKNGLEVHMERSEHGVSLAEDGALVIGSASASHSGDFKCVATNEAGSVERKTRLK 324 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 ++ QN G+ + L I V + +G + C A NSAG++ + + V Sbjct: 325 VLETPGVYLQN--GKRL-LKIYRVQHD-HAGRFSCTAQNSAGEAKREYTIEVQAPPVISG 380 Query: 932 KHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEIS--GMDHREIIQEGRXXXXXXX 987 + G+ V ++C+ S S +W H+ + +S G H E +++G+ Sbjct: 381 TSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQ--VLRVK 438 Query: 988 XXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFIRKLQDFEVKE--KDVAILEVEINS 1042 D G+ +C+ + +T + + P +D EV A+L E+ Sbjct: 439 SVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEG 498 Query: 1043 -ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE-- 1099 + W +D + I + + + G + L + D G Y+C + + TA Sbjct: 499 IPLPTITWLKDNQPI-VSSPQLTYTQGG--QSLRVAAARGEDAGAYTCRATNPAGTAHRH 555 Query: 1100 -VTVVELPPEI---ITRL----QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFS 1149 + +PP+I T L + +KV T L KG + + +WFKDG + + Sbjct: 556 YTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSC-LAKGFPEPVTQWFKDGQLLNGN 614 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 H L+++ L + + L G+Y+C V NS Sbjct: 615 THSGLSVN--SHMLHVDNAMLSHEGQYTCVVSNS 646 Score = 81.8 bits (193), Expect = 2e-13 Identities = 99/465 (21%), Positives = 184/465 (39%), Gaps = 46/465 (9%) Query: 1227 VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 VTW + I T FT++ + +R D YTC ++ L + V Sbjct: 121 VTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVV---DSKLYTCSAVNPAGNVSLTYNLQV 177 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P+I + G V L Q P P W+ N + + Sbjct: 178 QAKPRIHPAPSTLKALIGQTVVLPCVVQGEPSPQVSWLHNGLPV-----------ASDRM 226 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK--PNILEI----DSSSIN 1398 L I+ V+++D+G Y+ N+ G +++ + +L P+P + N LE+ ++ Sbjct: 227 LKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPAPQVRWFKNGLEVHMERSEHGVS 286 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS------IQN----LKTNSS 1448 + D G+++ + +++ + T E SV+ T+ + +QN LK Sbjct: 287 LAEDGALVIGSASASHSG-DFKCVATNEAGSVERKTRLKVLETPGVYLQNGKRLLKIYRV 345 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV---EKPLKNITTEPNEDIELTCIF 1505 A + + A E Y + ++Q+P V ++ +T +++++ C Sbjct: 346 QHDHAGRFSCTAQNSAGEAKREYTI----EVQAPPVISGTSGVQEVTIMAGQEVDMQCRV 401 Query: 1506 GGVPQPKVTWYRDGKKLKTAKATY----ENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P V W DG+ L + E Y+C+A N+ G Sbjct: 402 SGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAGTQTR 461 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + IQ P+I S ED + +G ++ +EGIP P + W K+ + + + + Sbjct: 462 QFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQ--L 519 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 T + +R+ + + YT A+N AGT+ TL++ P Sbjct: 520 TYTQGGQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPP 564 Score = 70.9 bits (166), Expect = 4e-10 Identities = 58/250 (23%), Positives = 99/250 (39%), Gaps = 15/250 (6%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 T+ C +G+P P WF+ ++ + + N L + G +TCV Sbjct: 587 TLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSV---NSHMLHVDNAMLSHEGQYTCVV 643 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 N+AG L ++ P H + D E P + + + V Sbjct: 644 SNSAGEDKRDFHLTIQVPPVFH---RVINGAADFTLGEREGD--EEDPDSPDGMVERREV 698 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 G I L C AIP P ++W +G ++ + + +A H +L+I V+ Sbjct: 699 LLGHSISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLA---PGH----ILQIPRVQLEDA 751 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 G YT AVN GE + L++ Q E ++ + +V L V G+P P+ Sbjct: 752 GKYTCQAVNEAGEDKMHYDLEVLVPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPS 811 Query: 766 ITWCKNNKPV 775 ++W K+ P+ Sbjct: 812 VSWIKDGLPL 821 Score = 67.3 bits (157), Expect = 4e-09 Identities = 106/483 (21%), Positives = 185/483 (38%), Gaps = 68/483 (14%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDE 800 M G VIL +V G+P P +TW +N + PV A T + I+ + +V D Sbjct: 99 MAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDV---RVVDS 155 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 +YT A N G + + V+ + P + T+ L V P Sbjct: 156 KLYTCSAVNPAGNVSLTYNLQVQAKPRIHPAP-------STLKALIGQTVVLPCVVQGEP 208 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P ++W N ++ + I+ V DSG Y+CVA NSAG+ + + Sbjct: 209 SPQVSWLHNGLPVASDRML-------KIQAV-----QHSDSGTYRCVARNSAGEDT--IQ 254 Query: 921 VTIDV-----EKVTFVK-----HLQKSYE----TEEGKTVILECQTSHT-----VSTK-- 959 + +DV +V + K H+++S E+G VI SH+ V+T Sbjct: 255 IVLDVLGSPAPQVRWFKNGLEVHMERSEHGVSLAEDGALVIGSASASHSGDFKCVATNEA 314 Query: 960 -WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETI 1016 K + ++ + + G C ++ E ++ Sbjct: 315 GSVERKTRLKVLETPGVYLQNGKRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQA 374 Query: 1017 PEFI---RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKY-DFEKRGHI 1071 P I +Q+ + ++ ++ V W DGE++ P + + +F ++G + Sbjct: 375 PPVISGTSGVQEVTIMAGQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQV 434 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVN--KGNKATF 1126 L +++ D G Y C+ + + T ++ P I ++ +V G A Sbjct: 435 --LRVKSVRPRDRGLYQCVATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVL 492 Query: 1127 EIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 E+ +G L + W KD I S + T G Q L++ +DAG Y+C N Sbjct: 493 HCEV-EGIPLPTITWLKDNQPIVSSPQLTYTQGG--QSLRVAAARGEDAGAYTCRATNPA 549 Query: 1185 CTA 1187 TA Sbjct: 550 GTA 552 Score = 67.3 bits (157), Expect = 4e-09 Identities = 94/451 (20%), Positives = 168/451 (37%), Gaps = 44/451 (9%) Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE--REYRIKRGSDVT 1306 KR L I + D ++C ++ K + + V+ PP I +E I G +V Sbjct: 337 KRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQEVTIMAGQEVD 396 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 + P P+ EW + +++ K L +K V D G+Y+ NN Sbjct: 397 MQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNA 456 Query: 1367 GHADVEMNVTILDKP--SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 G + +TI P G+ + + + + E E TI + D Sbjct: 457 GTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLK------DN 510 Query: 1425 TEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQ-- 1480 +S +T TQ Q+L+ ++ A A + A +Y +++ +I+ Sbjct: 511 QPIVSSPQLTYTQGG-QSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGD 569 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXX 1538 S + + N + L+C+ G P+P W++DG+ L T N Sbjct: 570 STILSFGRREEKVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSHMLHVD 629 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV----------ITI-----------SN 1577 Y C+ N GE + + IQ PV T+ S Sbjct: 630 NAMLSHEGQYTCVVSNSAGEDKRDFHLTIQVPPVFHRVINGAADFTLGEREGDEEDPDSP 689 Query: 1578 EDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKEL 1635 + + ++ +V G ++ IPPP + WY+ G +L + + +++I + Sbjct: 690 DGMVERREVLLGHSISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLAPGH---ILQIPRV 746 Query: 1636 KRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + KYT +A N AG + L+V P Sbjct: 747 QLEDAGKYTCQAVNEAGEDKMHYDLEVLVPP 777 Score = 65.7 bits (153), Expect = 1e-08 Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 15/179 (8%) Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXXXXXXXXXXXXXXXY 1548 + E ++ L C G P P VTW R+G+ + TA T Y Sbjct: 99 MAAEVGSEVILPCEVQGSPTPLVTWSRNGQTIPPVTAWFTMLPSGSLKISDVRVVDSKLY 158 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 C A N G V + + +Q KP I + +K +G ++ V++G P P+V W Sbjct: 159 TCSAVNPAGNVSLTYNLQVQAKPRIHPAPSTLKAL--IGQTVVLPCVVQGEPSPQVSWLH 216 Query: 1609 NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 NG + +D+ +++I+ ++ S S Y A N+AG ++++ L V P+ Sbjct: 217 NGLPVASDR-----------MLKIQAVQHSDSGTYRCVARNSAGEDTIQIVLDVLGSPA 264 Score = 64.9 bits (151), Expect = 2e-08 Identities = 87/370 (23%), Positives = 139/370 (37%), Gaps = 63/370 (17%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G C+VEG P P ITW + I S Q+ Y +L + EDAG +TC Sbjct: 487 GFPAVLHCEVEGIPLPTITWLKDNQPIVSSP--QLTYTQGG-QSLRVAAARGEDAGAYTC 543 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A N AG A L + P +EG S + + Sbjct: 544 RATNPAGTAHRHYTLRIMVPPQ-----------------------IEGDSTILSFGRREE 580 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V + L C PEP W G+ + + + +++ S M L + N Sbjct: 581 KVRINGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSHM------LHVDNAMLS 634 Query: 704 QEGTYTVVAVNREGEASLPIVLKI--------------------KTGEKEPPQVIEPL-K 742 EG YT V N GE L I + G++E P + + + Sbjct: 635 HEGQYTCVVSNSAGEDKRDFHLTIQVPPVFHRVINGAADFTLGEREGDEEDPDSPDGMVE 694 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHS---ITILKPKKVKD 799 V G S+ LS + P P ++W + + + T SDG + I + +++D Sbjct: 695 RREVLLGHSISLSCESNAIPPPRLSWYRQGRQL----TSSDGVVLAPGHILQIPRVQLED 750 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G YT +A N G + + V P + + F+ Q++ T+ L V+ + Sbjct: 751 AGKYTCQAVNEAGEDKMHYDLEVLVPPVISGQTDEFM---QDVDTVVNSTVSLRCDVSGH 807 Query: 860 PVPSITWYRN 869 P PS++W ++ Sbjct: 808 PSPSVSWIKD 817 Score = 53.2 bits (122), Expect = 8e-05 Identities = 78/360 (21%), Positives = 127/360 (35%), Gaps = 39/360 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G +L C + IP P I WL + IV ++ L++ + G Sbjct: 487 GFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQGGQS------LRVAAARGEDAGA 540 Query: 708 YTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPL--KSMIVRQGESVILSAQVVGNPRP 764 YT A N G A L+I + E I + VR ++ LS G P P Sbjct: 541 YTCRATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVRINGTLTLSCLAKGFPEP 600 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 W K+ + + + + + EG YT NS G + +T++ Sbjct: 601 VTQWFKDGQLLNGNTHSGLSVNSHMLHVDNAMLSHEGQYTCVVSNSAGEDKRDFHLTIQV 660 Query: 825 PT--------------------EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 P EE+ + P + +E+ + +I L P P + Sbjct: 661 PPVFHRVINGAADFTLGEREGDEEDPDSPDGMVERREVLLGH--SISLSCESNAIPPPRL 718 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 +WYR ++ S+ + L I V E D+G Y C A N AG+ + + Sbjct: 719 SWYRQGRQLTSSDGVVL---APGHILQIPRVQLE-DAGKYTCQAVNEAGEDKMHYDLEVL 774 Query: 925 VEKVTF--VKHLQKSYETEEGKTVILECQTS-H-TVSTKWYHNKKEISGMDHREIIQEGR 980 V V + +T TV L C S H + S W + + I+++G+ Sbjct: 775 VPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLPLYSDSRHNILEDGK 834 Score = 51.2 bits (117), Expect = 3e-04 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V +C+V G P P + W ++ P+ D + + + L ++ V P D G + C Sbjct: 392 GQEVDMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKG-QVLRVKSVRPRDRGLYQC 450 Query: 584 VAKNAAGFASSTTELIVE-APL---SDHGSEMTV 613 VA N AG + L ++ APL S SE+TV Sbjct: 451 VATNNAGTQTRQFRLTIQAAPLIRDSGEDSEVTV 484 Score = 51.2 bits (117), Expect = 3e-04 Identities = 36/139 (25%), Positives = 59/139 (42%), Gaps = 4/139 (2%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 I L+C +P P+++WYR G++L ++ Y C A N+ G Sbjct: 704 ISLSCESNAIPPPRLSWYRQGRQLTSSDGVVLAPGHILQIPRVQLEDAGKYTCQAVNEAG 763 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 E + + + PVI+ ++ Q V + + G P P V W K+G L + Sbjct: 764 EDKMHYDLEVLVPPVISGQTDEFMQDVDTVVNSTVSLRCDVSGHPSPSVSWIKDGLPLYS 823 Query: 1616 DKEYNITTKEKTSVIRIKE 1634 D +NI K + R+KE Sbjct: 824 DSRHNILEDGKL-LERLKE 841 Score = 49.2 bits (112), Expect = 0.001 Identities = 70/321 (21%), Positives = 128/321 (39%), Gaps = 26/321 (8%) Query: 1082 HDE-GEYSCILRDESCTA--EVTV-VELPPEI--ITRLQNQKVNKGNKATFEIELTKGDA 1135 HD G +SC ++ + A E T+ V+ PP I + +Q + G + + ++ G Sbjct: 347 HDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQEVTIMAGQEVDMQCRVS-GRP 405 Query: 1136 L--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----L 1189 L V W DG + + + K Q L++ D G Y C N+ T L Sbjct: 406 LPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNNAGTQTRQFRL 465 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDV 1248 T++ + + V A L E+ L +TW K I + + T Sbjct: 466 TIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPIVSSPQLTYTQG- 524 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEV---VEFPPKIVDY-EREYRIK 1300 ++L + +D YTC + T L++ V +E I+ + RE +++ Sbjct: 525 -GQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGDSTILSFGRREEKVR 583 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 +TL + FP+P +W + +++ H+ S++S L + + G Y Sbjct: 584 INGTLTLSCLAKGFPEPVTQWFKDGQLLNGNTHSGLSVNSH--MLHVDNAMLSHEGQYTC 641 Query: 1361 RLENNCGHADVEMNVTILDKP 1381 + N+ G + ++TI P Sbjct: 642 VVSNSAGEDKRDFHLTIQVPP 662 Score = 48.0 bits (109), Expect = 0.003 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 5/141 (3%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITI---SNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C A + G + + KP I S +K +VG E ++ ++G P P V Sbjct: 62 YICTATSAVGYTSREMHLIVNSKPRIVGADGSQVTVKMAAEVGSEVILPCEVQGSPTPLV 121 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W +NG + + T + ++I +++ S YT A N AG S+ L+V Sbjct: 122 TWSRNGQTIPPVTAW--FTMLPSGSLKISDVRVVDSKLYTCSAVNPAGNVSLTYNLQVQA 179 Query: 1665 KPSKPEGPVIMREISRESVTI 1685 KP P ++ + ++V + Sbjct: 180 KPRIHPAPSTLKALIGQTVVL 200 Score = 46.0 bits (104), Expect = 0.011 Identities = 55/240 (22%), Positives = 90/240 (37%), Gaps = 12/240 (5%) Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVE---EPSINFTLRLPEFILVPANTDA 1214 K+ LKIY D AG +SC NS + T+E P I+ T + E + + A + Sbjct: 337 KRLLKIYRVQHDHAGRFSCTAQNSAGEAKREYTIEVQAPPVISGTSGVQE-VTIMAGQEV 395 Query: 1215 YLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 + + L V W V+ + K + L ++ D+ Y CV + Sbjct: 396 DMQCRVSGRPLPSVEWTHDGEVLSPNGDPHVEFLEKGQVLRVKSVRPRDRGLYQCVATNN 455 Query: 1274 KSTTKLKVEV-VEFPPKIVD--YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 T + + ++ P I D + E + G L + + P P W+ +++ I Sbjct: 456 AGTQTRQFRLTIQAAPLIRDSGEDSEVTVVLGFPAVLHCEVEGIPLPTITWLKDNQPI-- 513 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNIL 1390 + + SL + DAG Y R N G A + I+ P G IL Sbjct: 514 VSSPQLTYTQGGQSLRVAAARGEDAGAYTCRATNPAGTAHRHYTLRIMVPPQIEGDSTIL 573 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V C+V+G P P +TW R I P ++ +L I +V D+ +TC Sbjct: 104 GSEVILPCEVQGSPTPLVTWSRNGQTIPP---VTAWFTMLPSGSLKISDVRVVDSKLYTC 160 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTV 613 A N AG S T L V+A H + T+ Sbjct: 161 SAVNPAGNVSLTYNLQVQAKPRIHPAPSTL 190 >UniRef50_UPI0000E46511 Cluster: PREDICTED: similar to Fibronectin type-III domain-containing protein 3a; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Fibronectin type-III domain-containing protein 3a - Strongylocentrotus purpuratus Length = 1345 Score = 114 bits (275), Expect = 2e-23 Identities = 120/451 (26%), Positives = 182/451 (40%), Gaps = 42/451 (9%) Query: 1616 DKEYNITTKEKTSVIRIK-ELKRSHSSKYTIEAS---------NTAGTS---SVEVTLKV 1662 DK+Y IT + +++ R + + SH S + + +S N G S S+ + Sbjct: 654 DKQYKITKLQPSTLYRFRLQAINSHGSSFYLYSSSINFDLCAFNEEGNSRWSSIVAFRTM 713 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRD 1722 D P P P + + S I W PP D GG E+T Y +EK E N + + R Sbjct: 714 PDAPRAPSKPSLKGKPHSTSFKIMWDPPRDCGGSEITSYQLEKAEVRNGPF---SPAYRG 770 Query: 1723 VE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 +E + L C Y RV + G S SE I T VP Sbjct: 771 MEREHQFDNLKPGCTYYLRVSCTSKGGASPC--SEVFSITTLPIVPGQSHTPRVHGKPKA 828 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRI 1839 SV + W + NGG+PI ++ VE+ + L TY FR+ Sbjct: 829 TSVNLRWGMPDYNGGAPITEFSVEMTAADNVTSEVHRATADITECTVNSLLPGRTYDFRL 888 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 + N+IG PY+ +++ G PP P S T+ V L W +P N G+ IT Sbjct: 889 RSCNKIGYG-PYSEPLRVSTG--AGPPDAPTELTASCVTTSVVLLSWQKPCFN-GADITE 944 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRL 1959 Y +E + G T + GS I ++ R+ A N G P S + Sbjct: 945 YRVEKASENG---TFSLAYSGSATTCEIRGLQPATYYYMRVQALNAAGHG-PFSS----V 996 Query: 1960 EKHATVPSPPTAPLEIRMVG--SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 T+PS P A +R+V S+ ++ W P D G+ ++ YN+ I + Sbjct: 997 ATCQTLPSSPEAVPSLRVVSSTSDSLLIQWTEPS-DCGSEIIAYNLDIGEGQPIF----- 1050 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 V+ N ++ + L + Y IR+ A N IG Sbjct: 1051 -VEGNVTQYCVDQLEPDTKYRIRVQALNSIG 1080 Score = 66.1 bits (154), Expect = 1e-08 Identities = 62/300 (20%), Positives = 121/300 (40%), Gaps = 18/300 (6%) Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG 1671 K + +++ + I+ L+ + ++A N AG PS PE Sbjct: 949 KASENGTFSLAYSGSATTCEIRGLQPATYYYMRVQALNAAGHGPFSSVATCQTLPSSPEA 1008 Query: 1672 PVIMREISR--ESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQ 1729 +R +S +S+ I+W P D G E+ Y ++ E + V+ +V YC+ Sbjct: 1009 VPSLRVVSSTSDSLLIQWTEPSDCGS-EIIAYNLDIGEG------QPIFVEGNVTQYCVD 1061 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789 +L + +Y RV A N +G + + +P ++S+ + W Sbjct: 1062 QLEPDTKYRIRVQALNSIGEGPYSAVLKAITRALPPIPPRLECVYYS----HQSLKLKWG 1117 Query: 1790 PSEKNGG-SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 + G S +++ +E++ + ++ ++ +LS +T+Y+FRI A NE GT Sbjct: 1118 DQNRIAGDSKSVNFTLEMEDKRGRFVVVYSGINLNQKVTRLSESTSYKFRILASNEAGTG 1177 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 PY+ D T PP + E S + W E + + +Y +++ + Sbjct: 1178 -PYSED--FVFATTKAPPVTLK-APTMEVDQDSCQISWAEAILHQQEDLMHYQCQYQRTR 1233 Score = 43.6 bits (98), Expect = 0.061 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 E N + + T+ D P P KP++ + S+S I WD P + G S I Y +E E Sbjct: 699 EGNSRWSSIVAFRTMPDAPRAPSKPSLKGKPHSTSFKIMWDPPRDCGGSEITSYQLEKAE 758 Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 + + + + NLK +Y R ++ S SE Sbjct: 759 VRNGPFSPAYRGMEREHQFDNLKPGCTYYLRVSCTSKGGASPCSE 803 Score = 37.5 bits (83), Expect = 4.0 Identities = 32/110 (29%), Positives = 49/110 (44%), Gaps = 10/110 (9%) Query: 1355 AGIYKLRLE--NNCGHADVEMNVTILDKPSPPGKPNILEIDSS---SINICWDEPENTGN 1409 A Y +R++ N GH T PS P L + SS S+ I W EP + G+ Sbjct: 975 ATYYYMRVQALNAAGHGPFSSVATCQTLPSSPEAVPSLRVVSSTSDSLLIQWTEPSDCGS 1034 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 I Y + +I + I V+ TQ + L+ ++ YR R A+N + Sbjct: 1035 EIIAYNL----DIGEGQPIFVEG-NVTQYCVDQLEPDTKYRIRVQALNSI 1079 >UniRef50_Q98902 Cluster: Neural cell adhesion molecule L1 precursor; n=7; Clupeocephala|Rep: Neural cell adhesion molecule L1 precursor - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 1277 Score = 114 bits (275), Expect = 2e-23 Identities = 154/710 (21%), Positives = 271/710 (38%), Gaps = 62/710 (8%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 PP + + +TV + + + NP P+ W ++ E PS E V Sbjct: 50 PPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSSV 109 Query: 892 ITNVDSEIDS-----GDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 + + +D+ G Y C ASN G + S+ A + ID V K + + + E G + Sbjct: 110 FYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMIDAPPVQ-QKEKKVTEKAEAGHS 168 Query: 946 VILEC---QTSHTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXXD-------- 993 + L C Q+S W N+ + I D + ++G + Sbjct: 169 IALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCNIQY 228 Query: 994 VGVIKCIVKDQETSTM----LVVKETIPEFIRKL---QDFEVKEKDVAILEVEINS-ETA 1045 + + K+ T T+ LV + P+ +R + LE + T Sbjct: 229 LATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGLPTP 288 Query: 1046 DVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVT 1101 V W R DGE+ + + +K F++R L N S D GEY C ++ + Sbjct: 289 KVSWLRKDGEMSESRISKDMFDRR-----LQFTNISESDGGEYQCTAENVQGRTFHTYTV 343 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKK 1160 VE P +Q G + + + W +G + ++ + Sbjct: 344 TVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTES 403 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 L + D D Y C+ N T + + + LP IL N + Y VE Sbjct: 404 GSLILKDVIFGDTAIYQCQASNKHGTILANTNV----YVIELPPQILTE-NGNTYTFVEG 458 Query: 1221 PDETLDVTWY---KKKSVIEDTEKFTLISDVKKRTLI-----IRKCTEDDQCEYTCVLLD 1272 L+ + K K E + L++D + L I + DD+ YTC++ Sbjct: 459 QKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNGGLEIANVSHDDEGIYTCLVQG 518 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQ---PNDEWIVNSKIIK 1329 + + +VEV+ I+ + R++ G Y P+ P +W N + I Sbjct: 519 SNISVNAEVEVLN-RTVILSPPQALRLQPGKTAIFTCLYVTDPKLSSPLLQWRKNDQKIF 577 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 + H+ L I VE D G+Y ++ + +T+ D+P PP + Sbjct: 578 E-SHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRPDPPVHLQV 636 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKNITKTQTSIQ-NLKTN 1446 + + W P + NS I+ YVVE+++ D E W +K + + + L Sbjct: 637 TNAKHRVVTLNW-TPGDDNNSPILEYVVEFEDQDMKENGWEELKRVAADKKHVNLPLWPY 695 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 SYRFR A+N+ SD S+ ++ YK + +P + +++ +T+P+ Sbjct: 696 MSYRFRVIAINDQGKSDPSKLSDLYKTPADAPDSNP---EDVRSESTDPD 742 Score = 101 bits (241), Expect = 3e-19 Identities = 143/580 (24%), Positives = 226/580 (38%), Gaps = 50/580 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP--DENISVAIESDMH 689 IPP + +P++ V D+++ C P P W GEE P D + V E+ Sbjct: 49 IPPAITTQPESVTVFSVEDLVMRCEASGNPSPTFHWTKDGEEFDPSSDPEMKVTEEAGSS 108 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 ++ ++ + K +G Y A N G A S VL I + P Q E + Sbjct: 109 VFYTLSNTMDTLKQYQGKYICYASNELGTAVSNAAVLMI---DAPPVQQKEKKVTEKAEA 165 Query: 749 GESVILSAQ-VVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITILKPKKVKDEGVY 803 G S+ LS + +P I W N L + DG+ + +L D Sbjct: 166 GHSIALSCNPPQSSMQPIIHWMDNRLRHIRLSDRVMVGKDGNLYFANLLTEDSRNDYTCN 225 Query: 804 TLKAENSEGIAETSAVITVEEP--TEENAEPPLFINRFQEITVKE-KG-TIKLVARVTRN 859 +A+ +TV N P + T +G T++L V Sbjct: 226 IQYLATRTILAKEPITLTVNPSNLVPRNRRPQMMRPTGSHSTYHALRGQTLELECIVQGL 285 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P ++W R + +S S FD L TN+ SE D G+Y+C A N G++ H Sbjct: 286 PTPKVSWLRKDGEMSESRISKDMFDR---RLQFTNI-SESDGGEYQCTAENVQGRTFH-- 339 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEIS--GMDHREI 975 T+ VE + + S G+TV L+CQ S W N +S ++ R Sbjct: 340 TYTVTVEASPYWTNAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRS 399 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKL-QDFEVKE 1030 + E D + +C ++ +T + V E P+ + + + E Sbjct: 400 LTE--SGSLILKDVIFGDTAIYQCQASNKHGTILANTNVYVIELPPQILTENGNTYTFVE 457 Query: 1031 KDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 A+LE E S V WE + + + G L I N S DEG Y+C Sbjct: 458 GQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNG---GLEIANVSHDDEGIYTC 514 Query: 1090 ILRDE--SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKD 1142 +++ S AEV TV+ PP+ + RLQ K + + L++W K+ Sbjct: 515 LVQGSNISVNAEVEVLNRTVILSPPQAL-RLQPGKTAIFT-CLYVTDPKLSSPLLQWRKN 572 Query: 1143 GSEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSCEV 1180 +I F +H + T DG L I + + D G Y+C++ Sbjct: 573 DQKI-FESHSDKKYTFDG--PGLIISNVEPGDEGVYTCQI 609 Score = 60.9 bits (141), Expect = 4e-07 Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 9/174 (5%) Query: 1497 EDIELTCIFGGVPQPKVTWYR-DGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 + +EL CI G+P PKV+W R DG+ + + +K ++ R Y+C A Sbjct: 274 QTLELECIVQGLPTPKVSWLRKDGEMSESRISKDMFDRR--LQFTNISESDGGEYQCTAE 331 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N G + V ++ P T N + Q + G+ + +GIP P + W NG L Sbjct: 332 NVQGRTFHTYTVTVEASPYWT--NAPVSQLYAPGETVKLDCQADGIPSPTITWTVNGVPL 389 Query: 1614 E-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 E + E S+I +K++ ++ Y +ASN GT + V + P Sbjct: 390 SATSLEPRRSLTESGSLI-LKDVIFGDTAIYQCQASNKHGTILANTNVYVIELP 442 Score = 46.4 bits (105), Expect = 0.009 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 H G T++ EC V+G P P+++W R+ + S+ + +D L + D G Sbjct: 269 HALRGQTLELECIVQGLPTPKVSWLRKDGEMSESRISKDMFD----RRLQFTNISESDGG 324 Query: 580 TFTCVAKNAAGFASSTTELIVEA 602 + C A+N G T + VEA Sbjct: 325 EYQCTAENVQGRTFHTYTVTVEA 347 Score = 46.0 bits (104), Expect = 0.011 Identities = 38/171 (22%), Positives = 64/171 (37%), Gaps = 10/171 (5%) Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTA----KATYENRXXXXXXXXXXXXXXXYKC 1550 P E ++L C G+P P +TW +G L + + Y+C Sbjct: 362 PGETVKLDCQADGIPSPTITWTVNGVPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQC 421 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 A N HG + + V + + P ++ G + L+ G P P+V W + Sbjct: 422 QASNKHGTILANTNVYVIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSS 481 Query: 1611 -NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT--IEASNTAGTSSVEV 1658 + L D N+ T + I + YT ++ SN + + VEV Sbjct: 482 ISLLLADPRVNLLT---NGGLEIANVSHDDEGIYTCLVQGSNISVNAEVEV 529 Score = 46.0 bits (104), Expect = 0.011 Identities = 46/203 (22%), Positives = 85/203 (41%), Gaps = 24/203 (11%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKG-EEIVPDENISVAIES 686 ++E P ++ EG LLEC P+P + W ++ D +++ Sbjct: 438 VIELPPQILTENGNTYTFVEGQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNG 497 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 L+I NV EG YT + + + + +T PPQ + + Sbjct: 498 G-------LEIANVSHDDEGIYTCLVQGSNISVNAEVEVLNRTVILSPPQALR------L 544 Query: 747 RQGESVILSAQVVGNPR---PTITWCKNNKPV-KALPTKS---DGDTHSITILKPKKVKD 799 + G++ I + V +P+ P + W KN++ + ++ K DG I+ ++P D Sbjct: 545 QPGKTAIFTCLYVTDPKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEP---GD 601 Query: 800 EGVYTLKAENSEGIAETSAVITV 822 EGVYT + + E S+ +T+ Sbjct: 602 EGVYTCQIITKLDMVEASSTLTL 624 Score = 41.9 bits (94), Expect = 0.19 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 5/93 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV+ +CQ +G P P ITW + + + +L++++V D + C Sbjct: 363 GETVKLDCQADGIPSPTITW-TVNGVPLSATSLEPRRSLTESGSLILKDVIFGDTAIYQC 421 Query: 584 VAKNAAG-FASSTTELIVEAP---LSDHGSEMT 612 A N G ++T ++E P L+++G+ T Sbjct: 422 QASNKHGTILANTNVYVIELPPQILTENGNTYT 454 Score = 41.5 bits (93), Expect = 0.25 Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 7/107 (6%) Query: 1852 TSDDKITIGKTLT---PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KT 1906 T D + TLT P P + V+ + R VTL WT P + SPI Y++EF + Sbjct: 611 TKLDMVEASSTLTLCDRPDPPVHLQVTNAKHRVVTLNWT-PGDDNNSPILEYVVEFEDQD 669 Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 +K W ++ V +H + FR+ A N G S P++ Sbjct: 670 MKENGWEELKRVAAD-KKHVNLPLWPYMSYRFRVIAINDQGKSDPSK 715 >UniRef50_UPI0000F1D6A2 Cluster: PREDICTED: hypothetical protein; n=3; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1495 Score = 113 bits (273), Expect = 4e-23 Identities = 93/400 (23%), Positives = 169/400 (42%), Gaps = 18/400 (4%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727 P + + E ++ V + WKPP+ G E Y +EK + W +V + + Sbjct: 556 PPTDLAVTEATKSYVVLSWKPPVQRGH-EGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFA 614 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L E+ Y FRV + N G E + E+ + LD+PS D+ SV + Sbjct: 615 LFDLAEDKSYTFRVRSCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDS-SVVV 673 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINTTYQ--FRIYARN 1843 W S++ ++ Y +E+ +G W R +N T + FR+ A N Sbjct: 674 CWGASKE--VKDLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVN 731 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 G S + + ++ PS P E + + W P GG+ I Y ++ Sbjct: 732 AAGYSGSSAESEACLVKASIAVPSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLD 791 Query: 1904 FKTVKG---KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSV 1957 ++TVK W ++ + + + ++KE + F++ A N G+ S+PT Sbjct: 792 YRTVKDGVTSKWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLEC 851 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + E VP PP L ++ V + ++ W P ++G +P+ GY + ++ W V Sbjct: 852 K-EWTVAVPGPPHG-LRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKE-ENGRWRCVQ 908 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + + L E +Y +RI+A+N G+ P ++ + Sbjct: 909 ERSTKHTYMKVSGLQEGISYRLRIHAKNLAGVGVPSKATD 948 Score = 92.3 bits (219), Expect = 1e-16 Identities = 88/327 (26%), Positives = 139/327 (42%), Gaps = 18/327 (5%) Query: 1637 RSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 RS +S E S G ++V L D PS P GPVI + SV + W + Sbjct: 629 RSCNSAGVGEPSEETGATTVGDRL---DLPSAP-GPVIPIRNTDSSVVVCWGASKEVK-- 682 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALES 1755 +L Y IE + W + + LN + FRV A N G+S + ES Sbjct: 683 DLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAES 742 Query: 1756 EPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK--QEG--K 1811 E ++K ++ VPS + + V I W K GG+ I Y ++ + ++G Sbjct: 743 EACLVKASIAVPSPPTGVTTLERLRDYMV-IGWQAPAKTGGADIRGYYLDYRTVKDGVTS 801 Query: 1812 KWKXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK-TLTPPSQ 1868 KW + ++ L N YQF++ A N+ G S + + T+ P Sbjct: 802 KWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGP 861 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-I 1927 P V E S+ + W P NG SP+T Y ++FK G+ W + V + H + + Sbjct: 862 PHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKEENGR-W-RCVQERSTKHTYMKV 919 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTES 1954 ++E RI A+N GV +P+++ Sbjct: 920 SGLQEGISYRLRIHAKNLAGVGVPSKA 946 Score = 89.8 bits (213), Expect = 7e-16 Identities = 74/295 (25%), Positives = 118/295 (40%), Gaps = 18/295 (6%) Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA---RIQKLSINTTYQFRIY 1840 V ++W P + G ++ Y + W+ + + L+ + +Y FR+ Sbjct: 570 VVLSWKPPVQRGHEGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVR 629 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 + N G P T+G L PS P + +T SV + W S + Y Sbjct: 630 SCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDSSVVVCWGA--SKEVKDLVGY 687 Query: 1901 IIEFKTVKGKS-WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQSVR 1958 IE TV G W + D+ FR+ A N G S ES++ Sbjct: 688 YIEV-TVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACL 746 Query: 1959 LEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI---AIRDVTKTMWME 2015 ++ VPSPPT + + +V+ W P GGA + GY + ++D + W E Sbjct: 747 VKASIAVPSPPTGVTTLERLRDYMVI-GWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHE 805 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE------PLESDEPFKVIPG 2064 + V + + + DL EN Y ++ A N+ G+SE PLE E +PG Sbjct: 806 LNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPG 860 Score = 73.7 bits (173), Expect = 5e-11 Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 7/165 (4%) Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 PE++WY+NG L + K ++ + + + + L + YT+ + +G + + Sbjct: 355 PEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVF 414 Query: 1662 VYDKPSKPEG----PVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V D + EG P+ +R + +++ V + WK P +G +T Y I++ E N+ W + Sbjct: 415 VRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQ 474 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIV 1759 D + + L E YMFRV A N G S + S+P+V Sbjct: 475 CNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVV 519 Score = 73.3 bits (172), Expect = 7e-11 Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 7/198 (3%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 PS P G + + R+ + I W+ P GG ++ Y ++ + K +++ T Sbjct: 754 PSPPTGVTTLERL-RDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVT 812 Query: 1726 ---YCIQKLNENCEYMFRVIAQNPVGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 Y + L EN Y F+V A N G SEA + + P+ K + Sbjct: 813 SSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGPPHGLRVQEVRK 872 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRI 1839 +S+ + W P NG SP+ Y V+ K+E +W+ ++ L +Y+ RI Sbjct: 873 DSMVVLWEPPTFNGRSPVTGYYVDFKEENGRWRCVQERSTKHTYMKVSGLQEGISYRLRI 932 Query: 1840 YARNEIGTSLPYTSDDKI 1857 +A+N G +P + D I Sbjct: 933 HAKNLAGVGVPSKATDAI 950 Score = 70.5 bits (165), Expect = 5e-10 Identities = 76/294 (25%), Positives = 127/294 (43%), Gaps = 36/294 (12%) Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV----VAVNREGEASLPI 723 L + +E V +E + + ++ S K+ VKK +E + +A++++ Sbjct: 131 LMETQEEVKEEGVGYVVMRNLFARESGFKMRTVKKTRETSMRESAERMALSQKLHEKEQF 190 Query: 724 VLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALP- 779 K+ PP+ I + V +G+SV L V G P+P + W KNN + KA P Sbjct: 191 QKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKNNVLIDAKARPE 250 Query: 780 ---TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE--EPTEENAEPP- 833 T+S + HS+ I K D Y + A N +G + A + ++ + EE E P Sbjct: 251 KYFTESQYNMHSLEI-KNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPH 309 Query: 834 ------------LFINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPS 876 I++F +E T+ L V P P I WYRN +S S Sbjct: 310 GYSPEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSS 369 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEK 927 + + ++ GE L + +++ E D G Y + +G +H A V + DVE+ Sbjct: 370 KWVHMHWSGEKATLTLVHLNKE-DEGLYTLRVNTKSGFDTHSAYVFVRDADVEE 422 Score = 64.5 bits (150), Expect = 3e-08 Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 28/228 (12%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F KP+ Q V EG + L C + P+P +AW +K ++ + ++ Sbjct: 202 PPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAW-YKNNVLIDAKARPEKYFTESQYNM 260 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEAS--LPIVLKIKTGEKE--------PPQ------ 736 L+I N Y + A+N +GE+S P+++K E+E P+ Sbjct: 261 HSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPHGYSPEYGVTFN 320 Query: 737 --VIEPLKSMIVRQGESVILSAQVVGNP-----RPTITWCKNNKPV---KALPTKSDGDT 786 +I+ R+GE++ L V+ P +P I W +N + K + G+ Sbjct: 321 TTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEK 380 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 ++T++ K +DEG+YTL+ G SA + V + E P+ Sbjct: 381 ATLTLVHLNK-EDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEGVPV 427 Score = 58.8 bits (136), Expect = 2e-06 Identities = 53/214 (24%), Positives = 85/214 (39%), Gaps = 8/214 (3%) Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTP--PSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 AR G S P+T K T P P + V+E+T V L W P G + Sbjct: 527 ARLRAGPSAPWTGVIKFTEEDPTVGVIPGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVM 586 Query: 1899 NYIIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQS 1956 Y +E V +W ++ T + + ++ E FR+ + N+ GV P+ E+ + Sbjct: 587 -YYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSEETGA 645 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV 2016 + +PS P + IR S++V+ WG + L+GY I + +W Sbjct: 646 TTVGDRLDLPSAPGPVIPIRNTDSSVVV-CWGASK--EVKDLVGYYIEVTVDGSGVWAPC 702 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 V +F L+ R+ A N G S Sbjct: 703 NNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYS 736 Score = 55.6 bits (128), Expect = 1e-05 Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 3/132 (2%) Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IVMTS 1986 ++ ++DE ++ + G + VR + P APL++R +N V+ + Sbjct: 387 HLNKEDEGLYTLRVNTKSGFDTHSAYVFVR-DADVEEEGVPVAPLDVRCHDANKDYVVVT 445 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P +G + + GY I +V W + V +F + L E +YM R+ A N Sbjct: 446 WKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARFPVTGLIEGRSYMFRVRALNN 505 Query: 2047 IGLSEPLESDEP 2058 G+S P +P Sbjct: 506 AGVSRPSRVSDP 517 Score = 53.6 bits (123), Expect = 6e-05 Identities = 45/238 (18%), Positives = 97/238 (40%), Gaps = 20/238 (8%) Query: 488 LNEKIDKLPVFEKPTSEEQ-SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 L++K+ + F+K + + + P F+ K R + +G +V C V G+P+P++ W++ Sbjct: 180 LSQKLHEKEQFQKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKN 239 Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 +I + Y+ + N+ +L I+ D + A N G +S+ +I++ Sbjct: 240 NVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFK 299 Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP--- 661 + I++ +F + EG + L C ++ P Sbjct: 300 EEEELVERPHGYSPEYGVTFNTTIIDKFDVSFGR--------EGETMSLGCTVIVYPTVK 351 Query: 662 --EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 +P+I W G + + + + + + L + ++ K EG YT+ + G Sbjct: 352 RYQPEIVWYRNGVALSSSKWVHMHWSGEK----ATLTLVHLNKEDEGLYTLRVNTKSG 405 Score = 53.6 bits (123), Expect = 6e-05 Identities = 60/283 (21%), Positives = 99/283 (34%), Gaps = 40/283 (14%) Query: 1227 VTWYKKKSVIEDT---EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 V WYK +I+ EK+ S +L I+ CT D EY L+ K + V Sbjct: 234 VAWYKNNVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPV 293 Query: 1284 V--------EFPPKIVDYEREYRI---------------KRGSDVTLLVDYQAFP----- 1315 + E + Y EY + + G ++L +P Sbjct: 294 IIKRFKEEEELVERPHGYSPEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRY 353 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 QP W N + K + A+LT+ + D G+Y LR+ G V Sbjct: 354 QPEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYV 413 Query: 1376 TILDK-------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 + D P P + + + + W +P G+S I Y ++ E+ W Sbjct: 414 FVRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWT 473 Query: 1429 SVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + + + + L SY FR A+N +S S ++ Sbjct: 474 QCNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSD 516 Score = 52.0 bits (119), Expect = 2e-04 Identities = 55/218 (25%), Positives = 84/218 (38%), Gaps = 31/218 (14%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P + ++ V + W +P G S IT Y I+ V WT+ Sbjct: 426 PVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARF 485 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE----------SQSVRL---------------E 1960 + + E +FR+ A N GVS P+ S RL E Sbjct: 486 PVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVVAMDPSDRARLRAGPSAPWTGVIKFTE 545 Query: 1961 KHATV---PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 + TV P PPT L + + V+ SW P G ++ Y + V W V Sbjct: 546 EDPTVGVIPGPPT-DLAVTEATKSYVVLSWKPPVQRGHEGVM-YYVEKCLVGTDAWQRVN 603 Query: 2018 K-VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + V + +F + DL+E+ +Y R+ + N G+ EP E Sbjct: 604 TGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSE 641 Score = 52.0 bits (119), Expect = 2e-04 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID---TTEW--ISVKNITK 1435 PSPP LE + I W P TG + I Y ++Y+ + T++W +++K +T Sbjct: 754 PSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVTS 813 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 + + +LK N Y+F+ A N+ IS+AS T Sbjct: 814 SPYKVTDLKENEFYQFQVRAFNQAGISEASIPT 846 Score = 50.8 bits (116), Expect = 4e-04 Identities = 69/280 (24%), Positives = 109/280 (38%), Gaps = 40/280 (14%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC---DLDDAGEYSCEVGNSKCTAILTVEE 1193 + WFKDG EI+ + I GK ++ +D DAG Y ++ + + + Sbjct: 1206 IAWFKDGIEIEEDDEDAKKI-GKSDEVLTFDIGKISKKDAGVYEVKLKDERGKDKTLLNL 1264 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPD-------------ETLDVTWYKKKSVIEDTE 1240 + L E V AN+ L V + E L V W K+S I ++ Sbjct: 1265 TDAGYQAVLNEVFRVIANSSTELKVMSTEHGIILYSFVVHYLEDLRVGWLHKESKISHSD 1324 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---------EFP---- 1287 + ++ L I + TE D+ +Y + D K + K +++ EF Sbjct: 1325 RVQCGVTGEQLWLKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKA 1384 Query: 1288 PKIVDYERE---------YRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPS 1337 I + R I+ G + L + P P WI N K ++ HT Sbjct: 1385 AAIAERNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKY 1444 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 SK AS+TI V TD+G Y L ++N G E V++ Sbjct: 1445 EHSKFASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSV 1484 Score = 47.6 bits (108), Expect = 0.004 Identities = 69/341 (20%), Positives = 131/341 (38%), Gaps = 47/341 (13%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGY-PRPQITWFRQ-TAIIKPSQDFQMYYDDDNVAT 567 P FVE L + TP+ V +C+V P +I WF+ I + +D + D V T Sbjct: 1175 PHFVEYLSFEVTPE-CDVHLKCKVGNIKPATEIAWFKDGIEIEEDDEDAKKIGKSDEVLT 1233 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 I ++ +DAG + K+ + G + T+ + Sbjct: 1234 FDIGKISKKDAGVYEVKLKD------------------ERGKDKTLLNLTDAGYQAVLNE 1275 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 + I + S + K + G IL + + + + WL K +I + + + + Sbjct: 1276 VFRVIANS-STELKVMSTEHGI-ILYSFVVHYLEDLRVGWLHKESKISHSDRVQCGVTGE 1333 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL-------------KIKTG---E 731 LKI + +G Y + + +G + L ++K E Sbjct: 1334 QLW----LKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKAAAIAE 1389 Query: 732 KEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTH 787 + +V+ L ++ +++G+S+ L+ V G+P P ++W KN KP+ + K + Sbjct: 1390 RNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKF 1449 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + + D G Y L +N G ++V P +E Sbjct: 1450 ASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSVYIPEDE 1490 Score = 46.0 bits (104), Expect = 0.011 Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 5/100 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKTQT 1438 P PP + E+ S+ + W+ P G S + Y V+++E + W + ++ T Sbjct: 859 PGPPHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKE-ENGRWRCVQERSTKHTYM 917 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + L+ SYR R +A N + S+ T+ ++ ET+ Sbjct: 918 KVSGLQEGISYRLRIHAKNLAGVGVPSKATD--AILAETR 955 Score = 43.6 bits (98), Expect = 0.061 Identities = 67/295 (22%), Positives = 125/295 (42%), Gaps = 48/295 (16%) Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184 FE K D+ W K+ S+ + + G K + D LDD G YSC V N+ Sbjct: 975 FECSDLKEDSQFVWSKNYEAFTDSSRLTIQTTGGKSRAIFNDPSLDDLGIYSCVVTNTDG 1034 Query: 1185 CTAILTVEEPSINFTLRLP---EFILVPANTDAYLTVEIPDE--------------TLDV 1227 +A T+ E + L + +F ++P ++ + +E+ ++ L V Sbjct: 1035 VSASYTLTEEGLKRLLDISHDHQFPIIPFKSE--MAIELQEKGRVRFWAEVGKFTSNLQV 1092 Query: 1228 TWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTE----DDQCEYTCVLLDAKSTTKLKVEV 1283 + +VI + +K+T+ + K T II + D+ +T L+D K+T + + + Sbjct: 1093 EYVFNDNVIHEGKKYTM--NFNKSTGIIEMFMDLLEVTDEGTFTFNLVDGKATGRTSLVL 1150 Query: 1284 V--EFP--PKIVDYER-EYRIKRGSDVTLLVDYQAFPQ-------------PNDE--WIV 1323 + EF K ++ER E+ ++G + ++ P+ P E W Sbjct: 1151 IGEEFAELQKKSEFERAEWVRRQGPHFVEYLSFEVTPECDVHLKCKVGNIKPATEIAWFK 1210 Query: 1324 NSKIIKKCKHTKPSIDSKSASLT--IKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 + I++ I LT I K+ DAG+Y+++L++ G +N+T Sbjct: 1211 DGIEIEEDDEDAKKIGKSDEVLTFDIGKISKKDAGVYEVKLKDERGKDKTLLNLT 1265 Score = 43.6 bits (98), Expect = 0.061 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650 +T + G P PEV W KN L D+ + + + K + I I + + S KY + N Sbjct: 1413 LTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDSGKYALLVKNK 1472 Query: 1651 AGTSSVEVTLKVY 1663 GT + E T+ VY Sbjct: 1473 YGTEAAEFTVSVY 1485 Score = 41.5 bits (93), Expect = 0.25 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP + E S + + W P G+ ++YY VE + T W V + + Sbjct: 554 PGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVMYY-VEKCLVGTDAWQRVNTGIPVKSPR 612 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETT 1468 ++ +L + SY FR + N + + SE T Sbjct: 613 FALFDLAEDKSYTFRVRSCNSAGVGEPSEET 643 Score = 39.9 bits (89), Expect = 0.75 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 7/102 (6%) Query: 513 VEKLRPKHTPDGSTVQFECQVEGYP-----RPQITWFRQTAIIKPSQDFQMYYDDDNVAT 567 ++K +G T+ C V YP +P+I W+R + S+ M++ + AT Sbjct: 324 IDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEK-AT 382 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHG 608 L + + ED G +T +GF + + + V +A + + G Sbjct: 383 LTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEG 424 Score = 37.9 bits (84), Expect = 3.0 Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +T++E ++ L V +P P ++W +N + + E T ++ + + DS Sbjct: 1403 VTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDS 1462 Query: 902 GDYKCVASNSAGKSSHGARVTIDV 925 G Y + N G + A T+ V Sbjct: 1463 GKYALLVKNKYG--TEAAEFTVSV 1484 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 4/107 (3%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435 LD PS PG + SS+ +CW + ++ Y +E + W N + Sbjct: 652 LDLPSAPGPVIPIRNTDSSVVVCWGASKEV--KDLVGYYIEVTVDGSGVWAPCNNKPVKG 709 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 T+ L FR AVN S +S +E V + SP Sbjct: 710 TRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACLVKASIAVPSP 756 >UniRef50_UPI00004D93F2 Cluster: immunoglobulin superfamily, member 10; n=3; Xenopus tropicalis|Rep: immunoglobulin superfamily, member 10 - Xenopus tropicalis Length = 2566 Score = 113 bits (273), Expect = 4e-23 Identities = 200/925 (21%), Positives = 355/925 (38%), Gaps = 84/925 (9%) Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGT 707 SD + C P P I W + V + M ++ + L I +V G Sbjct: 1607 SDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRV---NKMEVFMNGTLSIPSVGIQDGGQ 1663 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766 Y VA N+ G L + L + T PP++++ + + V G SV ++ Q G+P PTI Sbjct: 1664 YLCVANNQLGSDRLLVTLSVIT---YPPRILQGRSREITVHSGNSVNVNCQAEGSPFPTI 1720 Query: 767 TWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 TW N+ + + S+ I+K V D G+Y A N G E + + + Sbjct: 1721 TWTLKNETIPFGTSTSNRKIFVQPDGTLIIKDVTVYDRGIYRCLATNLAG--EDTFTVRI 1778 Query: 823 EEPTEENAEPPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYR-NNEIISPSETIT 880 + A PP+ + ++ + G +K+ NP P++ W + I P + + Sbjct: 1779 ----QVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVN 1834 Query: 881 QN-FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ---K 936 F N L I NV S D G+Y+C+A++S G + ++ + TF K K Sbjct: 1835 AKLFLFSNGTLYIRNVAS-TDRGNYECIATSSTGSERRVVNLIVE-QSDTFPKITDASPK 1892 Query: 937 SYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQEGRXXXXXXXXXXXX 992 + E G ++L C + + W K + HR IQ Sbjct: 1893 ATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDK 1952 Query: 993 DVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVK---EKDVAILEVEINSETAD 1046 D G C+ +++ ++++K ++ P I + Q + KD + S D Sbjct: 1953 DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQVPYGKDFKVDCKASGSPLPD 2012 Query: 1047 VVWE-RDGEIIKPKKNKYDF--EKRGHI----RKLYIRNTSVHDEGEYSCI----LRDES 1095 + W DG +I D KR +I LY+ + +EG+Y+C L + Sbjct: 2013 ISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLGRDE 2072 Query: 1096 CTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQ 1153 +TVV P I ++ + G + E + + W S++ +H + Sbjct: 2073 MKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIAISHDR 2132 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVE----EPSINFTLRLPEFIL 1207 + + L + L DAGEY C N T +L +E P IN I Sbjct: 2133 YLLH-ENGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYSNKSIIK 2191 Query: 1208 VPANTDAYLTVEIPDE---TLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 A + ++ E L V W ++ + + I + TL IR D Sbjct: 2192 DTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIRPSDT 2251 Query: 1264 CEYTCVLLD--AKSTTKLKVEVVEF--PPKIVDYEREYRIKRGSDVTLLVDY-QAFPQPN 1318 E+TCV + +S +++EV+E P + E I + S + +L + + P P Sbjct: 2252 AEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPE 2311 Query: 1319 DEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 W++ ++ + +K S + + I DAG Y+ N G+ + + + Sbjct: 2312 IIWLLPNGTRFLNGPSISKYHAGS-NGTFIIYSPTKDDAGKYRCAARNKVGYIEKLIILE 2370 Query: 1377 ILDKPS----PPGKPNILEIDSSSINICWDEPENTGNSTII--YYVVEYQEIDTTEWISV 1430 + KP+ P G + ++ S++ D + I+ Y +E ++ + Sbjct: 2371 VGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKLLE 2430 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 Q + + + N + + YA + + T V +I KP + Sbjct: 2431 NGTLVIQETALHDRGNYQCKAKNYA------GETAITVTVVVVAYPPRI----TNKPPQT 2480 Query: 1491 ITTEPNEDIELTCIFGGVPQPKVTW 1515 I T + L C+ G+P+P + W Sbjct: 2481 IHTRAGSAVRLNCMAIGIPKPDIFW 2505 Score = 96.7 bits (230), Expect = 6e-18 Identities = 163/792 (20%), Positives = 300/792 (37%), Gaps = 68/792 (8%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWL-FKGEEIVPDENISVAIES 686 ++ P +K + G ++ + C P+P + W+ F G +I P + ++ + Sbjct: 1780 VIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFL 1839 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + L I NV G Y +A + G + L ++ + P K+ + Sbjct: 1840 FSN---GTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPKATEM 1896 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802 G+ ++L+ G P+P I W +K V + ++ + + KD G Sbjct: 1897 NFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDKDAGD 1956 Query: 803 YTLKAENSEGIAETSAVITVE-EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y A N G ++V +P + + PL V K+ + + +P+ Sbjct: 1957 YLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQ------VPYGKDFKVDCKASGSPL 2010 Query: 862 PSITWYRN-----NEIISPSETITQN-----FDGENIELVITNVDSEIDSGDYKCVASNS 911 P I+W N I+ ++ + FD + L + E GDY C A N Sbjct: 2011 PDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEE---GDYTCYAENQ 2067 Query: 912 AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISG 969 G+ +T+ +++ Y G++VIL+C+ + K W ++ Sbjct: 2068 LGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIA 2127 Query: 970 MDH-REIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQD 1025 + H R ++ E D G C+ ++ +T + + P I L Sbjct: 2128 ISHDRYLLHEN--GSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYS 2185 Query: 1026 FEVKEKDVAILE----VEINSETA---DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 + KD AI ++ +E A V+W I L IRN Sbjct: 2186 NKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRN 2245 Query: 1079 TSVHDEGEYSCILRDES----CTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132 D E++C+ R++ ++ V+E+ P + + K +K + Sbjct: 2246 IRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAE 2305 Query: 1133 GDAL--VRW-FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185 G+ + W +G+ I G IY DDAG+Y C +VG + Sbjct: 2306 GNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEK 2365 Query: 1186 TAILTV-EEPSINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTWYKKKS-VIEDTEKF 1242 IL V ++P+I R P + I+ A + L+ +P + VTW IE + Sbjct: 2366 LIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGMPRPS--VTWILPSGYAIERPQVQ 2423 Query: 1243 TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKIVDY-EREYRI 1299 ++ TL+I++ D+ Y C + T + V VV +PP+I + + Sbjct: 2424 GRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPPRITNKPPQTIHT 2483 Query: 1300 KRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKH---TKPSIDSKSASLTIKKVENTDA 1355 + GS V L P+P+ W + + ++ T + +L I+ +++D+ Sbjct: 2484 RAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDS 2543 Query: 1356 GIYKLRLENNCG 1367 GIYK +N+ G Sbjct: 2544 GIYKCIAKNSLG 2555 Score = 82.2 bits (194), Expect = 1e-13 Identities = 157/788 (19%), Positives = 296/788 (37%), Gaps = 68/788 (8%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEI---VPDENISVAIESDMHMYCSVLKITNVK 701 V G+ + + C+ P P I W K E I N + ++ D L I +V Sbjct: 1700 VHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPD-----GTLIIKDVT 1754 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESVILSAQVVG 760 + G Y +A N GE + + +++ PP ++E + +++ GE++ + G Sbjct: 1755 VYDRGIYRCLATNLAGEDTFTVRIQVIAA---PPVIVEEKRQTVLAGPGENLKIPCTAKG 1811 Query: 761 NPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 NP+PT+ W + KP++ + K ++ ++ D G Y A +S G +E Sbjct: 1812 NPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTG-SER 1870 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW-YRNNEIISP 875 V + E ++ + + E+ +K + L T P P I W + ++ Sbjct: 1871 RVVNLIVEQSDTFPKITDASPKATEMNFGDK--LMLNCTATGEPKPRIIWRLPSKAVVDQ 1928 Query: 876 SETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL 934 + N L + +V+ + D+GDY CVA N G +V++ ++ ++ Sbjct: 1929 LHRMGSRIQVFPNGTLFVDSVNDK-DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQ 1987 Query: 935 QKSYETEEGKTVILECQTSHT--VSTKW-------YHN--KKEISGMDHREIIQEGRXXX 983 + + GK ++C+ S + W +N + + SG R I Sbjct: 1988 PLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTL 2047 Query: 984 XXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKLQD-FEVKEKDVAILEV 1038 + G C ++Q E + V P ++ + + IL+ Sbjct: 2048 YLNKVGIAEE-GDYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDC 2106 Query: 1039 EINSE-TADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR---- 1092 E N E + W ++I ++Y + G L + + D GEY C+ R Sbjct: 2107 EANGEPKPKIFWLLPSSDMIAISHDRYLLHENG---SLTVSQVKLLDAGEYMCVARNPAG 2163 Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL----TKGDA--LVRW-FKDGSE 1145 D++ + V PP I N+ + K +L +G A V W D Sbjct: 2164 DDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIY 2223 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF 1205 + H + + L+I + D E++C N ++L V+ + LR P F Sbjct: 2224 LTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEM-LRRPMF 2282 Query: 1206 -------ILVPANTDAYLTVEIP-DETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIR 1256 + ++ A L + T ++ W + + T II Sbjct: 2283 KNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIY 2342 Query: 1257 KCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDYER-EYRIKRGSDVTLLVDYQAF 1314 T+DD +Y C + KL + V P I+ + R + G ++L Sbjct: 2343 SPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSDGM 2402 Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P+P+ WI+ S + + ++ +L I++ D G Y+ + +N G + + Sbjct: 2403 PRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITV 2462 Query: 1374 NVTILDKP 1381 V ++ P Sbjct: 2463 TVVVVAYP 2470 Score = 80.2 bits (189), Expect = 6e-13 Identities = 177/823 (21%), Positives = 309/823 (37%), Gaps = 99/823 (12%) Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVAT 567 P+ VE+ R G ++ C +G P+P + W IKP Q + T Sbjct: 1785 PVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGT 1844 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 L IR V D G + C+A ++ G LIVE SD ++T Sbjct: 1845 LYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQ--SDTFPKIT--------------- 1887 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 PKA ++ G ++L C P+P I W + +V + + S Sbjct: 1888 ---------DASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLH---RMGSR 1935 Query: 688 MHMYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSM 744 + ++ + L + +V G Y VA N+ G+ I++K+ K P ++I +PL Sbjct: 1936 IQVFPNGTLFVDSVNDKDAGDYLCVARNKMGDD--VILMKVSVTMK-PAKIIQKQPLAKQ 1992 Query: 745 IVRQGESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGD---------THSITILKP 794 V G+ + + G+P P I+W + + + D + L Sbjct: 1993 -VPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTLYLNK 2051 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 + +EG YT AEN G E ITV A P + +N ++ L Sbjct: 2052 VGIAEEGDYTCYAENQLGRDEMKVHITV-----VTAAPLIKLNMKTRYAAMAGESVILDC 2106 Query: 855 RVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P P I W ++++I+ S + EN L ++ V +D+G+Y CVA N AG Sbjct: 2107 EANGEPKPKIFWLLPSSDMIAISH--DRYLLHENGSLTVSQV-KLLDAGEYMCVARNPAG 2163 Query: 914 KSSHGARVTID-----VEKVTFVKHLQKSYETEEGKTVI-LECQTSHTVSTKW-YHNKKE 966 + R+ + + + K + K + + +I + + + + W + Sbjct: 2164 DDTKLLRLEVHPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIY 2223 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK---- 1022 ++ H I + D C+ ++ +MLVV+ + E +R+ Sbjct: 2224 LTAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFK 2283 Query: 1023 ---LQDFEVKEKDVAILE-VEINSETADVVW---ERDGEIIKPKKNKYDFEKRGHIRKLY 1075 + F K +AIL + T +++W + P +KY G Sbjct: 2284 NPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNG---TFI 2340 Query: 1076 IRNTSVHDEGEYSCILRDE-SCTAEVTVVEL--PPEIITRLQNQKVNKGNKATFEIELTK 1132 I + + D G+Y C R++ ++ ++E+ P I+T + + +A L+ Sbjct: 2341 IYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKSIIGEALSLHCLSD 2400 Query: 1133 G--DALVRW-FKDGSEI---QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 G V W G I Q +L +G L I + L D G Y C+ N Sbjct: 2401 GMPRPSVTWILPSGYAIERPQVQGRYKLLENG---TLVIQETALHDRGNYQCKAKNYAGE 2457 Query: 1187 AILTVEEPSINFTLRL----PEFILVPANTDAYLT-VEIPDETLDVTW-YKKKSVIEDTE 1240 +TV + + R+ P+ I A + L + I D+ W SV+ Sbjct: 2458 TAITVTVVVVAYPPRITNKPPQTIHTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTAS 2517 Query: 1241 KFTLISDV---KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 + +L + TL+I+ D Y C+ ++ T K Sbjct: 2518 QGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLGTDMSK 2560 Score = 79.8 bits (188), Expect = 8e-13 Identities = 184/914 (20%), Positives = 339/914 (37%), Gaps = 77/914 (8%) Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNEII 873 T+ V T ++P + + TV + + NP P+I W + + + Sbjct: 1575 TTTVSTSFSTQNSRSKPRIIGGKAASFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFV 1634 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 S + + + N L I +V + D G Y CVA+N G +++ ++ Sbjct: 1635 SKTRRVNKMEVFMNGTLSIPSVGIQ-DGGQYLCVANNQLGSDRLLVTLSVITYPPRILQG 1693 Query: 934 LQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEI---SGMDHREIIQEGRXXXXXXXX 988 + G +V + CQ S + W + I + +R+I + Sbjct: 1694 RSREITVHSGNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQP-DGTLIIKD 1752 Query: 989 XXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-- 1043 D G+ +C+ + ++T T+ + P I + + V L++ ++ Sbjct: 1753 VTVYDRGIYRCLATNLAGEDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGN 1812 Query: 1044 -TADVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 V W DG IKP + LYIRN + D G Y CI S +E Sbjct: 1813 PQPTVHWVAFDGTKIKPLQYVNAKLFLFSNGTLYIRNVASTDRGNYECIATS-STGSERR 1871 Query: 1102 VVELPPEI------ITRLQNQ--KVNKGNKATFEIELTKGDALVR--WFKDGSEI----- 1146 VV L E IT + ++N G+K T G+ R W + Sbjct: 1872 VVNLIVEQSDTFPKITDASPKATEMNFGDKLMLNCTAT-GEPKPRIIWRLPSKAVVDQLH 1930 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRL 1202 + + IQ+ +G L + + DAG+Y C ++G+ ++V + Sbjct: 1931 RMGSRIQVFPNGT---LFVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQ 1987 Query: 1203 PEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKR--------TL 1253 P VP D + + L D++W + + S +KR TL Sbjct: 1988 PLAKQVPYGKDFKVDCKASGSPLPDISWSLPDGTMINNILQADDSGRRKRRYILFDNGTL 2047 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVE--VVEFPPKI-VDYEREYRIKRGSDVTLLVD 1310 + K ++ +YTC + ++KV VV P I ++ + Y G V L + Sbjct: 2048 YLNKVGIAEEGDYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCE 2107 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 P+P W++ S + H + + ++ SLT+ +V+ DAG Y N G Sbjct: 2108 ANGEPKPKIFWLLPSSDMIAISHDRYLLH-ENGSLTVSQVKLLDAGEYMCVARNPAGDDT 2166 Query: 1371 VEMNVTILDKPSPP------GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 + + + P PP +I++ + + + + G + + + I Sbjct: 2167 KLLRLEV--HPKPPIINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYL 2224 Query: 1425 TEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481 T I Q I+N++ + + F A N+ S E ++++ ++ Sbjct: 2225 TAPYHGSRILVHQNGTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKN 2284 Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKL----KTAKATYENRXXXX 1536 P EK + ++ L C G P P++ W +G + +K + Sbjct: 2285 PFNEK----FIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAGSNGTFI 2340 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP-VITISNEDIKQKHKVGDEWLVTAV 1595 Y+C A N G +E ++ + QKP ++T IK +G+ + + Sbjct: 2341 IYSPTKDDAGKYRCAARNKVGYIEKLIILEVGQKPNILTHPRGPIKS--IIGEALSLHCL 2398 Query: 1596 IEGIPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 +G+P P V W +G +E + + + I+E Y +A N AG + Sbjct: 2399 SDGMPRPSVTWILPSGYAIERPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGET 2458 Query: 1655 SVEVTLKVYDKPSK 1668 ++ VT+ V P + Sbjct: 2459 AITVTVVVVAYPPR 2472 Score = 77.4 bits (182), Expect = 4e-12 Identities = 205/988 (20%), Positives = 376/988 (38%), Gaps = 90/988 (9%) Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTHSITILKPKKVK 798 S V + + GNP PTI W K + T K + + + ++ Sbjct: 1600 SFTVLANSDAFIPCEASGNPSPTILWTKVSSGTFVSKTRRVNKMEVFMNGTLSIPSVGIQ 1659 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G Y A N G ++T+ T P + R +EITV ++ + + Sbjct: 1660 DGGQYLCVANNQLG--SDRLLVTLSVIT---YPPRILQGRSREITVHSGNSVNVNCQAEG 1714 Query: 859 NPVPSITWYRNNEIISPSETITQN---FDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 +P P+ITW NE I P T T N F + L+I +V + D G Y+C+A+N AG+ Sbjct: 1715 SPFPTITWTLKNETI-PFGTSTSNRKIFVQPDGTLIIKDV-TVYDRGIYRCLATNLAGED 1772 Query: 916 SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWY-HNKKEISGMDH 972 + R+ + V+ +++ G+ + + C + + + W + +I + + Sbjct: 1773 TFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKIKPLQY 1832 Query: 973 -REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVV------KETIPEFI-RKLQ 1024 + D G +CI S VV +T P+ + Sbjct: 1833 VNAKLFLFSNGTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFPKITDASPK 1892 Query: 1025 DFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIR-KLYIRNTSVH 1082 E+ D +L E ++W + + + ++ + L++ + + Sbjct: 1893 ATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTLFVDSVNDK 1952 Query: 1083 DEGEYSCILR----DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL- 1136 D G+Y C+ R D+ +V+V P +II + K K F+++ G L Sbjct: 1953 DAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPLAKQVPYGK-DFKVDCKASGSPLP 2011 Query: 1137 -VRW-FKDGSEIQFSNHIQLTIDGKKQK---------LKIYDCDLDDAGEYSC----EVG 1181 + W DG+ I +N +Q G++++ L + + + G+Y+C ++G Sbjct: 2012 DISWSLPDGTMI--NNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEGDYTCYAENQLG 2069 Query: 1182 NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKS-VIEDT 1239 + +TV + L + A L E E + W S +I + Sbjct: 2070 RDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFWLLPSSDMIAIS 2129 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD-AKSTTK-LKVEVVEFPPKIVD-YERE 1296 L+ + +L + + D EY CV + A TK L++EV PP I Y + Sbjct: 2130 HDRYLLHE--NGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPPIINGLYSNK 2187 Query: 1297 YRIKRGS--DVTLLVDYQAFPQPNDE--WIVNSKI-IKKCKHTKPSIDSKSASLTIKKVE 1351 IK + L+D +A + WI+ I + H + ++ +L I+ + Sbjct: 2188 SIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQNGTLEIRNIR 2247 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILD---KP---SPPGKPNILEIDSSSINICWDEPE 1405 +D + N+ G + + + + +L+ +P +P + I + +I C+ E Sbjct: 2248 PSDTAEFTCVARNDGGESMLVVQLEVLEMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGN 2307 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT-NSSYRFRAYAVNEVDISDA 1464 T II+ + IS + T I T + + ++R A N+V + Sbjct: 2308 PT--PEIIWLLPNGTRFLNGPSISKYHAGSNGTFIIYSPTKDDAGKYRCAARNKVGYIEK 2365 Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-----YRDG 1519 E + K + P P+K+I E + L C+ G+P+P VTW Y Sbjct: 2366 LIILEVGQ--KPNILTHP--RGPIKSII---GEALSLHCLSDGMPRPSVTWILPSGYAIE 2418 Query: 1520 KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED 1579 + + Y+C A N GE + V + P I+N+ Sbjct: 2419 RPQVQGRYKLLENGTLVIQETALHDRGNYQCKAKNYAGETAITVTVVVVAYPP-RITNKP 2477 Query: 1580 IKQKH-KVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKEYNITTKE---KTSVIRIKE 1634 + H + G + + GIP P++ W + + L + ++T E + I+ Sbjct: 2478 PQTIHTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQN 2537 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 + S S Y A N+ GT + L V Sbjct: 2538 PQSSDSGIYKCIAKNSLGTDMSKTYLNV 2565 Score = 54.0 bits (124), Expect = 4e-05 Identities = 135/642 (21%), Positives = 227/642 (35%), Gaps = 58/642 (9%) Query: 1074 LYIRNTSVHDEGEYSCI----LRDESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEI 1128 L I + + D G+Y C+ L + ++V+ PP I+ R + V+ GN Sbjct: 1651 LSIPSVGIQDGGQYLCVANNQLGSDRLLVTLSVITYPPRILQGRSREITVHSGNSVNVNC 1710 Query: 1129 ELTKGD-ALVRWFKDGSEIQF----SNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + + W I F SN I + DG L I D + D G Y C N Sbjct: 1711 QAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPDGT---LIIKDVTVYDRGIYRCLATN 1767 Query: 1183 -----SKCTAILTVEEPSINFTLRLPEFILVPA-NTDAYLTVE-IPDETLDVTWY---KK 1232 + I + P + + + P N T + P T+ + K Sbjct: 1768 LAGEDTFTVRIQVIAAPPVIVEEKRQTVLAGPGENLKIPCTAKGNPQPTVHWVAFDGTKI 1827 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPP 1288 K + K L S+ TL IR D+ Y C+ + + + L VE + P Sbjct: 1828 KPLQYVNAKLFLFSN---GTLYIRNVASTDRGNYECIATSSTGSERRVVNLIVEQSDTFP 1884 Query: 1289 KIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASL 1345 KI D + + G + L P+P W + SK + H S + +L Sbjct: 1885 KITDASPKATEMNFGDKLMLNCTATGEPKPRIIWRLPSKAVVDQLHRMGSRIQVFPNGTL 1944 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPE 1405 + V + DAG Y N G + M V++ KP+ + L + + D Sbjct: 1945 FVDSVNDKDAGDYLCVARNKMGDDVILMKVSVTMKPAKIIQKQPL---AKQVPYGKDFKV 2001 Query: 1406 NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + S + + D T + NI + S + + + +N+V I++ Sbjct: 2002 DCKASGSPLPDISWSLPDGT---MINNILQADDSGRRKRRYILFDNGTLYLNKVGIAEEG 2058 Query: 1466 ETTEY---------YKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTW 1515 + T Y KV +P ++ +K E + L C G P+PK+ W Sbjct: 2059 DYTCYAENQLGRDEMKVHITVVTAAPLIKLNMKTRYAAMAGESVILDCEANGEPKPKIFW 2118 Query: 1516 Y---RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPV 1572 D + + Y C+A N G+ + + KP Sbjct: 2119 LLPSSDMIAISHDRYLLHENGSLTVSQVKLLDAGEYMCVARNPAGDDTKLLRLEVHPKPP 2178 Query: 1573 I---TISNED-IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN-KLENDKEYNITTKEKT 1627 I SN+ IK L+ EG P +V+W N L + + Sbjct: 2179 IINGLYSNKSIIKDTAIKHSRKLIDCKAEGAAPLQVMWIMPDNIYLTAPYHGSRILVHQN 2238 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP 1669 + I+ ++ S ++++T A N G S + V L+V + +P Sbjct: 2239 GTLEIRNIRPSDTAEFTCVARNDGGESMLVVQLEVLEMLRRP 2280 Score = 47.2 bits (107), Expect = 0.005 Identities = 40/184 (21%), Positives = 71/184 (38%), Gaps = 17/184 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L C +P P + W+ + + + + L I G Sbjct: 2390 GEALSLHCLSDGMPRPSVTWILPSGYAIERPQVQGRYKL---LENGTLVIQETALHDRGN 2446 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTI 766 Y A N GE ++ + + + PP++ +P +++ R G +V L+ +G P+P I Sbjct: 2447 YQCKAKNYAGETAITVTVVVVA---YPPRITNKPPQTIHTRAGSAVRLNCMAIGIPKPDI 2503 Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPK--------KVKDEGVYTLKAENSEGIAETSA 818 W + L T S G +L P+ + D G+Y A+NS G + Sbjct: 2504 FW--ELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSSDSGIYKCIAKNSLGTDMSKT 2561 Query: 819 VITV 822 + V Sbjct: 2562 YLNV 2565 Score = 46.4 bits (105), Expect = 0.009 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 6/84 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAII---KPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 G++V CQ EG P P ITW + I + + +++ D TL+I++V D G Sbjct: 1703 GNSVNVNCQAEGSPFPTITWTLKNETIPFGTSTSNRKIFVQPD--GTLIIKDVTVYDRGI 1760 Query: 581 FTCVAKNAAGFASSTTEL-IVEAP 603 + C+A N AG + T + ++ AP Sbjct: 1761 YRCLATNLAGEDTFTVRIQVIAAP 1784 Score = 45.6 bits (103), Expect = 0.015 Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 11/119 (9%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTP-DGSTVQFECQ 532 + +E +YT Y + +L D++ V + AP+ ++ ++ G +V +C+ Sbjct: 2054 IAEEGDYTCYAENQLGR--DEMKVHITVVTA----APLIKLNMKTRYAAMAGESVILDCE 2107 Query: 533 VEGYPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 G P+P+I W ++ +I S D + +++ +L + +V DAG + CVA+N AG Sbjct: 2108 ANGEPKPKIFWLLPSSDMIAISHDRYLLHEN---GSLTVSQVKLLDAGEYMCVARNPAG 2163 Score = 43.6 bits (98), Expect = 0.061 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 520 HTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPE 576 HT GS V+ C G P+P I W +++ + + + TLVI+ Sbjct: 2482 HTRAGSAVRLNCMAIGIPKPDIFWELPDLSVLSTASQGSLTGTELLHPQGTLVIQNPQSS 2541 Query: 577 DAGTFTCVAKNAAGFASSTTELIV 600 D+G + C+AKN+ G S T L V Sbjct: 2542 DSGIYKCIAKNSLGTDMSKTYLNV 2565 Score = 40.3 bits (90), Expect = 0.57 Identities = 49/188 (26%), Positives = 73/188 (38%), Gaps = 12/188 (6%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-----ILKPKKVKDEGVY 803 G +V + +V+G P P I W + P S +IT ILK D G+Y Sbjct: 487 GGTVEMDCEVLGEPTPAIEWILPDGSKIRAPYASQEGRITITKNGKFILKSADNFDTGIY 546 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 A N S ITV E F+N E++V I L + P S Sbjct: 547 HCIATNYIDADVLSFRITVVSSDVEEQ----FVNGV-ELSVSNGDYINLPCGSSGVPDAS 601 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++W + + E N L I + SE DSG ++C+A+N G RV + Sbjct: 602 VSWILPDHSVL-YEPSRNKIILANGTLKIQGI-SERDSGHFRCLAANQYGLDILTHRVLV 659 Query: 924 DVEKVTFV 931 ++ + Sbjct: 660 KERQINVI 667 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 3/89 (3%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQF-ECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDD 562 E P+F K S + C EG P P+I W Y+ Sbjct: 2275 EMLRRPMFKNPFNEKFIAKSSKMAILNCFAEGNPTPEIIWLLPNGTRFLNGPSISKYHAG 2334 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGF 591 N T +I +DAG + C A+N G+ Sbjct: 2335 SN-GTFIIYSPTKDDAGKYRCAARNKVGY 2362 >UniRef50_P98160 Cluster: Basement membrane-specific heparan sulfate proteoglycan core protein precursor; n=26; Eumetazoa|Rep: Basement membrane-specific heparan sulfate proteoglycan core protein precursor - Homo sapiens (Human) Length = 4391 Score = 113 bits (272), Expect = 5e-23 Identities = 178/814 (21%), Positives = 311/814 (38%), Gaps = 104/814 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 PI++E H +G T+ C V G Q+TW+++ + P++ + + L Sbjct: 2926 PIYIEA-SSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSL-PARH------QTHGSQLR 2977 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + V P D+G + C A + G V P S+ GS + Sbjct: 2978 LHLVSPADSGEYVCRAASGPG-PEQEASFTVTVPPSE-GSSYRLRS-------------- 3021 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEP-DIAWLFKGEEIVPDENISVAIESDM 688 P S P + V +G D +C + P + W + +E+ ++N+ ++ Sbjct: 3022 ----PVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL--EDNVHISPNG-- 3073 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVR 747 S++ I + GTY VA N G A + L + PP V + P + V+ Sbjct: 3074 ----SIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHG----PPTVSVLPEGPVWVK 3125 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTL 805 G++V L G PR + W + + L ++ G D+H++ + K D G Y Sbjct: 3126 VGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVC 3185 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A+N+ G A+ + V+ P + E+TV+ T L T +P P+I Sbjct: 3186 LAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEE-AELTVEAGHTATLRCSATGSPAPTIH 3244 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W +++ SP +G+ L+I V + DSG Y C A++ AG + A + + V Sbjct: 3245 W---SKLRSPLPW-QHRLEGDT--LIIPRVAQQ-DSGQYICNATSPAGHAE--ATIILHV 3295 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXX 983 E + + + + G+TV L+C T ++ +W + G R Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGR------ATARNEL 3349 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE 1043 D G +C V ++ S + + L + ++V E Sbjct: 3350 LHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLE 3409 Query: 1044 TADVVWERDGEIIKPKKNKYD---FEKRGHIRK--------LYIRNTSVHDEGEYSCILR 1092 T + + P F++ G + L I+N +G Y C Sbjct: 3410 TKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAH 3469 Query: 1093 DE----SCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSE 1145 +A++ + LP +I R Q V G+ FE L GD V W K G Sbjct: 3470 GPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFEC-LALGDPKPQVTWSKVGG- 3527 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT----AILTVEE-PSINFTL 1200 H++ I ++I +L DAG+Y C N+ T +L V+ P I+ Sbjct: 3528 -----HLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQIS--- 3579 Query: 1201 RLPEFILVPANTDA-YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 +P+ + VPA + A + + T D++W K + S ++ L++ Sbjct: 3580 -MPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPD------SRLENNMLMLPSVR 3632 Query: 1260 EDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDY 1293 D Y C + + K ++ P ++V Y Sbjct: 3633 PQDAGTYVCTATNRQGKVKAFAH-LQVPERVVPY 3665 Score = 99.1 bits (236), Expect = 1e-18 Identities = 260/1257 (20%), Positives = 443/1257 (35%), Gaps = 187/1257 (14%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV+ C+ G P ITW ++ + P Q + ++ATL+I + DAG + C Sbjct: 1970 GRTVRLYCRAAGVPSATITWRKEGGSLPP----QARSERTDIATLLIPAITTADAGFYLC 2025 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 VA + AG A + + +V SD PP + + Sbjct: 2026 VATSPAGTAQARIQ-VVVLSASDAS------------------------PPPVKIESSSP 2060 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V EG + L C + + W +G + P + + S L++ V Sbjct: 2061 SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV----------HGSRLRLPQVSPA 2110 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-----------IEPLKSMIVRQGESV 752 G Y N G I + + G P IEP S V +G+++ Sbjct: 2111 DSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTL 2169 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVKDEGVYTLKAENSE 811 L+ V G +TW K +LP + TH S+ L D G Y + Sbjct: 2170 DLNCVVPGQAHAQVTWHKRG---GSLPARH--QTHGSLLRLHQVTPADSGEYVCHVVGTS 2224 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G E S ++T+E PP+ I TV E T+ L V +TWY+ Sbjct: 2225 GPLEASVLVTIEASVIPGPIPPVRIES-SSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGG 2283 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-------SHGARVTID 924 + + G + + S D+G Y C ASN S + GA + Sbjct: 2284 SLPARHQVR----GSRLYIFQA---SPADAGQYVCRASNGMEASITVTVTGTQGANLAYP 2336 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWYH--NKKEISGMDHREIIQEG 979 ++ S + EG+T+ L C SH T W+ + H +++ Sbjct: 2337 AGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVT-WHKRGGSLPVRHQTHGSLLRLY 2395 Query: 980 RXXXXXXX----XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI 1035 + V + ++ E + + P + +V E Sbjct: 2396 QASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLD 2455 Query: 1036 LEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 L + + A V W + G + P +++ H +L + + D GEY C + Sbjct: 2456 LNCLVAGQAHAQVTWHKRGGSL-PARHQV------HGSRLRLLQVTPADSGEYVCRVVGS 2508 Query: 1095 SCTAEVTVVELPPEIIT-----------RLQNQKVNKGNKATFEIE---LTKGDALVRWF 1140 S T E +V+ + ++ R+++ + N T ++ ++ + W+ Sbjct: 2509 SGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWY 2568 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE---- 1192 K G + S H I G +L+I D+GEY C V G+ + + I+T++ Sbjct: 2569 KRGGSLP-SRH---QIVG--SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622 Query: 1193 --EPSINFTLRLPEF--ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE-------K 1241 PS++ +R+ +V T V +TWYK+ + + Sbjct: 2623 SHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLR 2682 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR 1301 +S + R D E + V+ + S P +I Sbjct: 2683 LHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGE 2742 Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 D+ +V QA Q W + T+ S L + V D+G Y R Sbjct: 2743 TLDLNCVVPGQAHAQVT--WHKRGGSLPSHHQTRGS------RLRLHHVSPADSGEYVCR 2794 Query: 1362 LENNCGHADVEMNVTI-------LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 + + G + + VTI + P+P G P I I+ SS + G + + Sbjct: 2795 VMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPI-RIEPSSSRVA------EGQTLDLK 2847 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQN--LKTN--SSYRFRAYAVNEVDISDASETTEY 1470 VV Q W + + L+ N S Y+ S E + Sbjct: 2848 CVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVL 2907 Query: 1471 YKVIKET--KIQSPTVEKPL----KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 + + I +P + +P+ + + ++L C+ G +VTWY+ G L Sbjct: 2908 VTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPA 2967 Query: 1525 AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-EVETSCVVGIQ---------QKPVIT 1574 T+ ++ Y C A + G E E S V + + PVI+ Sbjct: 2968 RHQTHGSQ--LRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVIS 3025 Query: 1575 IS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 I + ++Q + L+ +G P + W +LE+ N+ S+I I Sbjct: 3026 IDPPSSTVQQGQDASFKCLIH---DGAAPISLEWKTRNQELED----NVHISPNGSIITI 3078 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVIMREISRESVTIE 1686 + S+ Y ASN G + V L V+ P+ PEGPV ++ ++VT+E Sbjct: 3079 VGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVK--VGKAVTLE 3133 Score = 90.6 bits (215), Expect = 4e-16 Identities = 265/1244 (21%), Positives = 452/1244 (36%), Gaps = 190/1244 (15%) Query: 505 EQSMAPIFVEKLRPKHT--PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 E + AP+ VE + P + P G + CQV G P W R+ PS Q + Sbjct: 1671 ETNQAPLVVE-VHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1729 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV-EAPLSDHGSEMTVXXXXXXXX 621 + L V P DAG + C +N +S EL+V EAP +TV Sbjct: 1730 E----LHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAP----SKPITV-----TVE 1776 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 + G TF K++ + L+ RL P A F G I+ N+ Sbjct: 1777 EQRSQSVRPGADVTFICTAKSK---SPAYTLVWTRLHNGKLPTRAMDFNG--ILTIRNVQ 1831 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 + SD Y V +N+ +GT T + V G S P+V PPQ Sbjct: 1832 L---SDAGTY--VCTGSNMFAMDQGTAT-LHVQASGTLSAPVV------SIHPPQ----- 1874 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH-SITILKPKKVKDE 800 + V+ G+ G+P PT+ W P LP K+ H I L + D+ Sbjct: 1875 --LTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQLPAKA--QIHGGILRLPAVEPTDQ 1928 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 Y +A +S G AV+ V P + ++ + V T++L R P Sbjct: 1929 AQYLCRAHSSAGQQVARAVLHV----HGGGGPRVQVSP-ERTQVHAGRTVRLYCRAAGVP 1983 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 +ITW + + P + +I ++ + D+G Y CVA++ AG + AR Sbjct: 1984 SATITWRKEGGSLPPQ----ARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQ--AR 2037 Query: 921 VTIDVEKVTF-----VKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR 973 + + V + VK S EG+T+ L C + + + WY + H Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLP--PHT 2095 Query: 974 EIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETS-TMLVVKET--------IPEFI 1020 ++ D G C V++ +E S T+ V+ T +P Sbjct: 2096 QV----HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGST 2151 Query: 1021 RKLQ----DFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 R ++ V E L + + A V W + G + P ++ + G + +L+ Sbjct: 2152 RPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSL-PARH----QTHGSLLRLH 2206 Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEII------TRLQNQKVNKGNKATFEI 1128 + D GEY C + S E +V V + +I R+++ T ++ Sbjct: 2207 --QVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDL 2264 Query: 1129 ELT---KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKC 1185 + A V W+K G + + + + +L I+ DAG+Y C N Sbjct: 2265 SCVVAGQAHAQVTWYKRGGSLPARHQV------RGSRLYIFQASPADAGQYVCRASNGME 2318 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD------------VTWYKKK 1233 +I + L P P + + +TLD VTW+K+ Sbjct: 2319 ASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRG 2378 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP------ 1287 + L + + + D EY C +L + + V V P Sbjct: 2379 G------SLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPA 2432 Query: 1288 ----PKIVDYEREYRIKRGS--DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 P + ++ G D+ LV QA Q W + +H Sbjct: 2433 LGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVT--WHKRGGSL-PARH-----QVH 2484 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI---LEIDSSSIN 1398 + L + +V D+G Y R+ + G + + VTI + S + + I+SSS + Sbjct: 2485 GSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSAS 2544 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWI-------SVKNITKTQTSIQNLKTNSSYRF 1451 + G++ + +V Q T W S I ++ I + S + Sbjct: 2545 LA------NGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEY 2598 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP----NEDIELTCIFGG 1507 + N + + ET+ + P+V P++ ++ P + ++L C+ Sbjct: 2599 VCHVSNG---AGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVAR 2655 Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 PQ +TWY+ G L + T+ + Y C A N+ +E S V+ + Sbjct: 2656 QPQAIITWYKRGGSLPSRHQTHGSH--LRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713 Query: 1568 QQ---KPVITISNEDIK----QKHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEY 1619 P S+ I+ H E L + V+ G +V W+K G L + + Sbjct: 2714 SPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ- 2772 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTLK 1661 + S +R+ + + S +Y ++G +SV VT++ Sbjct: 2773 -----TRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIE 2811 Score = 87.8 bits (208), Expect = 3e-15 Identities = 205/1006 (20%), Positives = 354/1006 (35%), Gaps = 118/1006 (11%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G+ PT + + V EG + L C + + W +G ++ + + Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGG----------SLPARHQV 2483 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLK----SM 744 + S L++ V G Y V G EAS+ + ++ + V P++ S Sbjct: 2484 HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSA 2543 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGV 802 + G ++ L+ V TITW K +LP++ G I + P D G Sbjct: 2544 SLANGHTLDLNCLVASQAPHTITWYKRG---GSLPSRHQIVGSRLRIPQVTP---ADSGE 2597 Query: 803 YTLKAENSEGIAETSAVITVEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 Y N G ETS ++T++ + PP+ I TV E T+ L V R Sbjct: 2598 YVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIES-SSPTVVEGQTLDLNCVVARQ 2656 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P ITWY+ + PS T G ++ L + S DSG+Y C A+N+ Sbjct: 2657 PQAIITWYKRGGSL-PSRHQTH---GSHLRL---HQMSVADSGEYVCRANNNIDALEASI 2709 Query: 920 RVTIDVE--------KVTFVKHLQKSYETEEGKTVILECQT---SHTVSTKWY------- 961 +++ ++ S EG+T+ L C +H T W+ Sbjct: 2710 VISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVT-WHKRGGSLP 2768 Query: 962 -HNKKEIS--GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018 H++ S + H G + V+ I ++ + P Sbjct: 2769 SHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPP 2828 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 + V E L+ + + A V W + G + P +++ H L + Sbjct: 2829 IRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNL-PARHQV------HGPLLRLN 2881 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV-VELPPE-------------IITRLQNQKVNKGNK 1123 S D GEYSC + S T E +V V + P I + V +G Sbjct: 2882 QVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQT 2941 Query: 1124 ATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + + A V W+K G + + H +L+++ D+GEY C + Sbjct: 2942 LDLNCVVPGQAHAQVTWYKRGGSLP-ARH-----QTHGSQLRLHLVSPADSGEYVCRAAS 2995 Query: 1183 S---KCTAILTVEEP---SINFTLRLPEFILVPANT------DAYLTVEIPD--ETLDVT 1228 + A TV P ++ LR P + P ++ DA I D + + Sbjct: 2996 GPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLE 3055 Query: 1229 WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFP 1287 W + +ED + + + I + Y CV +A + V + V P Sbjct: 3056 WKTRNQELEDNVHISPNGSI----ITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGP 3111 Query: 1288 PKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 P + V E +K G VTL P+ + W S K + + A L Sbjct: 3112 PTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQ 3171 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 I + +DAG Y +N G A ++ V + PG P + + + + + + Sbjct: 3172 ISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQV-QAEEAELTV------E 3224 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 G++ + T W +++ Q ++ T R + I +A+ Sbjct: 3225 AGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEG-DTLIIPRVAQQDSGQY-ICNATS 3282 Query: 1467 TTEYYKVIKETKIQSPTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 + + ++SP + ++ + + E ++L C+ G P W R G L Sbjct: 3283 PAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSL-PG 3341 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 +AT N Y+C N G E + +Q P Sbjct: 3342 RATARNE-LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPP 3386 Score = 79.8 bits (188), Expect = 8e-13 Identities = 237/1247 (19%), Positives = 431/1247 (34%), Gaps = 144/1247 (11%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 ++ + S P+ +E P T +G T+ C V G Q+TW+R+ + P + Sbjct: 2044 SASDASPPPVKIESSSPSVT-EGQTLDLNCVVAGSAHAQVTWYRRGGSLPP-------HT 2095 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 + + L + +V P D+G + C +N +G ++ + V HG+ Sbjct: 2096 QVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL-----HGTHSGPSYTP---- 2146 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 + G +P + +V EG + L C + + W +G Sbjct: 2147 -------VPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGG--------- 2190 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIE 739 ++ + + S+L++ V G Y V G EAS+ + ++ P V Sbjct: 2191 -SLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRI 2249 Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799 S V +G+++ LS V G +TW K +LP + + I + D Sbjct: 2250 ESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG---GSLPARHQVRGSRLYIFQASPA-D 2305 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-----TVKEKGTIKLVA 854 G Y +A N E S +TV N P + I V E T+ L Sbjct: 2306 AGQYVCRASNG---MEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNC 2362 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V +TW++ S + G + L S DSG+Y C S+ Sbjct: 2363 VVPGQSHAQVTWHKR----GGSLPVRHQTHGSLLRLYQA---SPADSGEYVCRVLGSSVP 2415 Query: 915 SSHGARVTID-------VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967 VTI+ + V+ S + EG+T+ L C + + +K+ Sbjct: 2416 LEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRG- 2474 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV----KDQETSTMLVVKETIPEFIRKL 1023 + R + R D G C V QE S ++ +++ + + Sbjct: 2475 GSLPARHQVHGSR---LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQG 2531 Query: 1024 QDFEVK-EKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHI--RKLYIRNTS 1080 + V+ E A L + +V + I K R I +L I + Sbjct: 2532 VAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVT 2591 Query: 1081 VHDEGEYSCILRDESCTAEVTVV------------ELPPEIITRLQNQKVNKGNKATFE- 1127 D GEY C + + + + E +++ + P I + V +G Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNC 2651 Query: 1128 IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS---- 1183 + + A++ W+K G + S H L+++ + D+GEY C N+ Sbjct: 2652 VVARQPQAIITWYKRGGSLP-SRH-----QTHGSHLRLHQMSVADSGEYVCRANNNIDAL 2705 Query: 1184 KCTAILTV-------EEPSINFTLRLPEFILVPANTDAY-LTVEIPDET-LDVTWYKKKS 1234 + + +++V P + +R+ A + L +P + VTW+K+ Sbjct: 2706 EASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGG 2765 Query: 1235 VI---EDTEKFTL----ISDVKKRTLIIRKCTEDDQCEYT-CVLLDAKSTTKLKVEVVEF 1286 + T L +S + R E + V ++A ++ + V Sbjct: 2766 SLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGG 2825 Query: 1287 PPKIVDYEREYRIKRGS--DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 P I R+ G D+ +V QA Q W K+ + Sbjct: 2826 APPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVT--W------HKRGGNLPARHQVHGPL 2877 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSP---PGKPNILEIDSSSINIC 1400 L + +V D+G Y ++ + G + + VTI P P PG + I++SS ++ Sbjct: 2878 LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHV- 2936 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWI----SVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 G + + VV Q W S+ +T S L S Y Sbjct: 2937 -----TEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVC 2991 Query: 1457 NEVDISDASETTEYYKVIKETK-----IQSPTVEKPLKNITTEPNEDIELTC-IFGGVPQ 1510 + + + ++ ++SP + + T + +D C I G Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAP 3051 Query: 1511 PKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 + W ++L+ N Y+C+A N +G ++ + + Sbjct: 3052 ISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGP 3111 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI 1630 P +++ E KVG + V G P W + + ++ + +V+ Sbjct: 3112 PTVSVLPEG-PVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVL 3170 Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 +I K S + Y A N GT+ +V + V P P + E Sbjct: 3171 QISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAE 3217 Score = 77.4 bits (182), Expect = 4e-12 Identities = 158/752 (21%), Positives = 274/752 (36%), Gaps = 88/752 (11%) Query: 472 QYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFEC 531 +Y+ NN L+ + I P P++ SM PI +E H +G T+ C Sbjct: 2693 EYVCRANNNIDALEASI--VISVSPSAGSPSAPGSSM-PIRIES-SSSHVAEGETLDLNC 2748 Query: 532 QVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 V G Q+TW ++ + PS + + L + V P D+G + C ++G Sbjct: 2749 VVPGQAHAQVTWHKRGGSL-PS------HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGP 2801 Query: 592 ASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDI 651 ++ + +EA GS G PP +P + V EG + Sbjct: 2802 LEASVLVTIEA----SGS------------SAVHVPAPGGAPP-IRIEPSSSRVAEGQTL 2844 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 L+C + + W +G + P + ++ +L++ V G Y+ Sbjct: 2845 DLKCVVPGQAHAQVTWHKRGGNL-PARH---------QVHGPLLRLNQVSPADSGEYSCQ 2894 Query: 712 AVNREGEASLPIVLKIKTGEKEP---PQVIEPL----KSMIVRQGESVILSAQVVGNPRP 764 G +++ I+ P P + +P+ S V +G+++ L+ V G Sbjct: 2895 VTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHA 2954 Query: 765 TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +TW K + A ++ G + ++ P D G Y +A + G E A TV Sbjct: 2955 QVTWYKRGGSLPA-RHQTHGSQLRLHLVSP---ADSGEYVCRAASGPG-PEQEASFTVTV 3009 Query: 825 PTEENA----EPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYRNNEIISPSETI 879 P E + P+ TV++ + P S+ W N+ + + I Sbjct: 3010 PPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHI 3069 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS-Y 938 + N G I +V T + G Y+CVASN+ G + + V + V V L + Sbjct: 3070 SPN--GSIITIVGTRPSNH---GTYRCVASNAYGVAQ--SVVNLSVHGPPTVSVLPEGPV 3122 Query: 939 ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 + GK V LEC ++ S +W + ++ R D G Sbjct: 3123 WVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGT 3182 Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEII 1056 C+ ++ + V E I + + + A L VE TA + G Sbjct: 3183 YVCLAQNALGTAQKQV-EVIVDTGAMAPGAPQVQAEEAELTVEA-GHTATLRCSATGSPA 3240 Query: 1057 -----KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPE 1108 ++ ++ R L I + D G+Y C + AE T+ VE PP Sbjct: 3241 PTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPY 3300 Query: 1109 IITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 T ++ V G + L G +W + GS + + + L Sbjct: 3301 ATTVPEHASVQAGETVQLQC-LAHGTPPLTFQWSRVGSSLPG------RATARNELLHFE 3353 Query: 1167 DCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194 +D+G Y C +VG+++ A L V+ P Sbjct: 3354 RAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP 3385 Score = 73.7 bits (173), Expect = 5e-11 Identities = 217/1116 (19%), Positives = 390/1116 (34%), Gaps = 139/1116 (12%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P P+ V G + L CR +P I W +G + P + +D+ + Sbjct: 1956 PRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQAR---SERTDI----A 2008 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPI-VLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I + G Y VA + G A I V+ + + PP V S V +G+++ Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSE 811 L+ V G+ +TW + +LP + H + P+ D G Y + EN Sbjct: 2069 DLNCVVAGSAHAQVTWYRRG---GSLPPHT--QVHGSRLRLPQVSPADSGEYVCRVENGS 2123 Query: 812 GIAETSAVITVEEPTEE--------NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 G E S ++V T + P+ I V E T+ L V Sbjct: 2124 GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP-SSSHVAEGQTLDLNCVVPGQAHAQ 2182 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +TW++ + P+ T L+ + + DSG+Y C ++G VTI Sbjct: 2183 VTWHKRGGSL-PARHQTHG------SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235 Query: 924 DVE----KVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQ 977 + + V+ S EG+T+ L C + + WY K + R ++ Sbjct: 2236 EASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWY---KRGGSLPARHQVR 2292 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKD-QETSTMLVVKET----IPEFIRKLQDFEVKEKD 1032 R D G C + E S + V T + Q ++ Sbjct: 2293 GSR---LYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSS 2349 Query: 1033 VAILE---VEIN-----SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 + E +++N A V W + G + P ++ + G + +LY S D Sbjct: 2350 SQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL-PVRH----QTHGSLLRLY--QASPADS 2402 Query: 1085 GEYSCILRDESCTAEVTVV-------ELPPEIIT---RLQNQKVNKGNKATFEIE-LTKG 1133 GEY C + S E +V+ +P +T R+++ T ++ L G Sbjct: 2403 GEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAG 2462 Query: 1134 D--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTA 1187 A V W K G + + + +L++ D+GEY C V G + + Sbjct: 2463 QAHAQVTWHKRGGSLPARHQVH------GSRLRLLQVTPADSGEYVCRVVGSSGTQEASV 2516 Query: 1188 ILTVEE-------PSINFTLRLPEFILVPANTDAY-LTVEIPDET-LDVTWYKKKSVIED 1238 ++T+++ + + +R+ AN L + + +TWYK+ + Sbjct: 2517 LVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPS 2576 Query: 1239 TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYER 1295 + V R L I + T D EY C + + + + + V + Sbjct: 2577 RHQI-----VGSR-LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSP 2630 Query: 1296 EYRIKRGSDVTL---LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 RI+ S + +D + I+ K+ + + L + ++ Sbjct: 2631 PIRIESSSPTVVEGQTLDLNCVVARQPQAIIT--WYKRGGSLPSRHQTHGSHLRLHQMSV 2688 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTI---LDKPSPPGKPNILEIDSSSINICWDEPENTGN 1409 D+G Y R NN + + +++ PS PG + I+SSS ++ E E Sbjct: 2689 ADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVA--EGETLDL 2746 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + ++ Q S+ + +T+ S L S Y + S E + Sbjct: 2747 NCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASV 2806 Query: 1470 YYKV----IKETKIQSPTVEKPLK----NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK 1521 + + +P P++ + + ++L C+ G +VTW++ G Sbjct: 2807 LVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGN 2866 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIK 1581 L + Y C G +E S +V I+ I + Sbjct: 2867 LPARHQVH--GPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLA 2924 Query: 1582 Q--------KHKVGDEWL-VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 Q H + L + V+ G +V WYK G L + + S +R+ Sbjct: 2925 QPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTH------GSQLRL 2978 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + + S +Y A++ G E + V PS+ Sbjct: 2979 HLVSPADSGEYVCRAASGPGPEQ-EASFTVTVPPSE 3013 Score = 73.3 bits (172), Expect = 7e-11 Identities = 89/415 (21%), Positives = 159/415 (38%), Gaps = 54/415 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TVQ +C G P W R + + + L PED+G + C Sbjct: 3313 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARN-------ELLHFERAAPEDSGRYRC 3365 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 N G A + +L+V+ P GS I G PT P+ + Sbjct: 3366 RVTNKVGSAEAFAQLLVQGP---PGS-------------LPATSIPAGSTPTVQVTPQLE 3409 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 G+ + C + + + W +G ++ P ++ VL+I N+ + Sbjct: 3410 TKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDG----------VLRIQNLDQS 3459 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 +GTY A G+A L I+ + +++++V G +V +G+P+ Sbjct: 3460 CQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVV--GHAVEFECLALGDPK 3517 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P +TW K ++ +S G + + ++ D G Y A N+ G ++ ++ V+ Sbjct: 3518 PQVTWSKVGGHLRPGIVQSGG----VVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ 3573 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 A P I+ QE+ V + P P I+W + + + P + Sbjct: 3574 ------ALPQ--ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRL---- 3621 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 EN L++ +V + D+G Y C A+N GK A + + V + S+ Sbjct: 3622 --ENNMLMLPSVRPQ-DAGTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTPYSF 3673 Score = 53.2 bits (122), Expect = 8e-05 Identities = 92/435 (21%), Positives = 153/435 (35%), Gaps = 49/435 (11%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-------EFPPKIVDYEREYRIKRGSDV 1305 L I D Y C+ +A T + +VEV+ P++ E E ++ G Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLEN 1364 TL P P W K + P + +L I +V D+G Y + Sbjct: 3230 TLRCSATGSPAPTIHW-------SKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATS 3282 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 GHA+ + IL SPP + E +S+ G + + + T Sbjct: 3283 PAGHAEATI---ILHVESPPYATTVPE--HASVQ--------AGETVQLQCLAHGTPPLT 3329 Query: 1425 TEWISVKNITKTQTSIQN-------LKTNSSYRFRAYAVNEVDISDASETTEYYKV---I 1474 +W V + + + +N S R+R N+V ++A + Sbjct: 3330 FQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSL 3389 Query: 1475 KETKI---QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 T I +PTV+ + T +E C ++ W+++G +L + + Sbjct: 3390 PATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDG 3449 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C A G+ + S + IQ P + I+ Q VG Sbjct: 3450 --VLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVE 3507 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + G P P+V W K G L + V+RI ++ + + +Y A+N A Sbjct: 3508 FECLALGDPKPQVTWSKVGGHLRPG------IVQSGGVVRIAHVELADAGQYRCTATNAA 3561 Query: 1652 GTSSVEVTLKVYDKP 1666 GT+ V L V P Sbjct: 3562 GTTQSHVLLLVQALP 3576 Score = 46.4 bits (105), Expect = 0.009 Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV F C G P P I W I PS + TL+IR+V D G +TC Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHI-PSHPRVTVTSEGGRGTLIIRDVKESDQGAYTC 479 Query: 584 VAKNAAGFASSTTELIVE 601 A NA G + ++E Sbjct: 480 EAMNARGMVFGIPDGVLE 497 Score = 44.8 bits (101), Expect = 0.026 Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 734 PPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSIT 790 PPQV+ P + I +G++V + +G P P I W N + + P T + Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464 Query: 791 ILKPKKVKDEGVYTLKAENSEGI 813 I++ K D+G YT +A N+ G+ Sbjct: 465 IIRDVKESDQGAYTCEAMNARGM 487 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%) Query: 1550 CIAFNDHGEVETSCV-----VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 CI + H + E+ C G V+T E I+ G T V G+P P + Sbjct: 381 CIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASR--GQTVTFTCVAIGVPTPII 438 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 W N + + +T++ + I+++K S YT EA N G Sbjct: 439 NWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARG 486 >UniRef50_UPI0000F1EF3F Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 3366 Score = 113 bits (271), Expect = 7e-23 Identities = 142/664 (21%), Positives = 247/664 (37%), Gaps = 75/664 (11%) Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIY 1166 II +++ V G A FE + D V W DG IQ + + ++ DGK+ +L + Sbjct: 831 IIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLN 890 Query: 1167 DCDLDDAGEYSC-------EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 DD+G Y+C E+ +S ++ EP FT +L ++ + Sbjct: 891 SVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPL--FTRKLDVLEVIEGRNARFDCKV 948 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLII---------------RKCTEDDQC 1264 V W +E+ E ++ + + +LII R +D+C Sbjct: 949 SGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNEDEGLYTVAARNSHGEDEC 1008 Query: 1265 EYTCVLLDAKSTTKLKVEVVEFPPKIVDYER--EYRIKR-----------------GSDV 1305 + + + ++ +E P I + E I+R G + Sbjct: 1009 AAELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREA 1068 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 L P P W N K I + K + SL ++ V + G+YK + N Sbjct: 1069 VLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCVISNK 1128 Query: 1366 CGHADVEMNVTILD-KPSPP-GKPNILEIDSSSINICWDEPENTGNS---TIIYYVVEYQ 1420 G A ++ + D P PP G P + I +I + W +P+ S + + Y ++ Q Sbjct: 1129 VGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYAIQQQ 1188 Query: 1421 EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 + + +W + + K T +I NL Y FR ++ S S TE +++ Sbjct: 1189 ALGSIQWTIIASCLKQTTYTISNLSKGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPY 1248 Query: 1480 --QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE------N 1531 ++P + + + + +T V VTW R G L +E + Sbjct: 1249 VQEAPVIIDKPDIVYMVEKQPLSITVTLNHV-NASVTWKRGGVTLSNRPGLFELSMPDDD 1307 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK--PVITISNEDIKQKHKVGDE 1589 + CIA N +G SCV+ ++ P ED+ VG+ Sbjct: 1308 QHTLKLCKVKSSDVGQLTCIANNKYGS--DSCVLTLEMAVAPTFETIMEDLDVN--VGET 1363 Query: 1590 WLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 V+EG P P+++WYK L + + + + + S YT A N Sbjct: 1364 PRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKN 1423 Query: 1650 TAGTSSVEVTLKVY--------DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 AG+ S + L V+ D P + E I+R++ R + + + G K Sbjct: 1424 LAGSVSCKAELTVHTSKHLKDKDDPMEDEAS-ILRKMRRLTDYYDVHKEIGRGAFSYVKR 1482 Query: 1702 AIEK 1705 I+K Sbjct: 1483 VIQK 1486 Score = 91.1 bits (216), Expect = 3e-16 Identities = 113/528 (21%), Positives = 203/528 (38%), Gaps = 31/528 (5%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S+ P+F KL +G +F+C+V G P PQ+ W ++ ++D ++ + Sbjct: 922 SIEPLFTRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGR-H 980 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623 +L+I V ED G +T A+N+ G EL V+ P +S +++ Sbjct: 981 SLIISHVSNEDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEV 1040 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +I P F K V EG + +L C++ +P P I W G+ I E+ + Sbjct: 1041 PENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMT 1100 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 D+H L + V G Y V N+ G+A+ L + +PP ++S Sbjct: 1101 QFRDVHS----LVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILPDPPDGAPVVES 1156 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK----D 799 + G+++ LS + P+I ++ S T + LK Sbjct: 1157 I---TGKTITLSWKKPKRLDPSIDPSSLMYAIQQQALGSIQWTIIASCLKQTTYTISNLS 1213 Query: 800 EGV---YTLKAENSEGIAETSAVITVEEPTEEN---AEPPLFINRFQEITVKEKGTIKLV 853 +GV + + + S+ ++ S + + E P+ I++ + + EK + + Sbjct: 1214 KGVRYAFRVLSITSKAFSKPSPATEPMQLLDRGPYVQEAPVIIDKPDIVYMVEKQPLSIT 1273 Query: 854 ARVTRNPV-PSITWYRNNEIIS--PSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 VT N V S+TW R +S P D + L + V S D G C+A+N Sbjct: 1274 --VTLNHVNASVTWKRGGVTLSNRPGLFELSMPDDDQHTLKLCKVKSS-DVGQLTCIANN 1330 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNKKEIS 968 G S +T+++ + + + + G+T + + WY +S Sbjct: 1331 KYGSDS--CVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLS 1388 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI 1016 H + + D GV C K+ S + T+ Sbjct: 1389 ESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436 Score = 80.2 bits (189), Expect = 6e-13 Identities = 77/304 (25%), Positives = 125/304 (41%), Gaps = 42/304 (13%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVK 701 V G L EC ++ + D+ WL G+ I P + MH C +L + +V Sbjct: 840 VKAGETALFECHVIGPQDTDVDWLSDGKLIQP-----ALLNCKMHFDGKRCRLL-LNSVH 893 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + GTYT + E + LK+ + P L + V +G + +V G Sbjct: 894 EDDSGTYTCKLSTAKEELTSSAKLKVIASIE--PLFTRKLDVLEVIEGRNARFDCKVSGT 951 Query: 762 PRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P P + W ++P++ + +G HS+ I+ +DEG+YT+ A NS G E +A Sbjct: 952 PPPQVIWSHFDRPLEENEDIRILKEGGRHSL-IISHVSNEDEGLYTVAARNSHGEDECAA 1010 Query: 819 VITVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKL 852 + V+EP EE P P F+ ++ V E L Sbjct: 1011 ELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVL 1070 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 +V P P+ITW+ N + I +E + ++ ++ G YKCV SN Sbjct: 1071 RCKVAGLPYPTITWFHNGKRIDSTED-RKMTQFRDVHSLVVRCVCHAHGGVYKCVISNKV 1129 Query: 913 GKSS 916 GK++ Sbjct: 1130 GKAT 1133 Score = 73.3 bits (172), Expect = 7e-11 Identities = 62/202 (30%), Positives = 90/202 (44%), Gaps = 17/202 (8%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNP-RPTITWCK-----NNKPVKALPTKSDGD 785 +E P +I+ K IV E LS V N ++TW + +N+P + D D Sbjct: 1250 QEAPVIID--KPDIVYMVEKQPLSITVTLNHVNASVTWKRGGVTLSNRPGLFELSMPDDD 1307 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 H++ + K K D G T A N G S V+T+E A P F +++ V Sbjct: 1308 QHTLKLCKVKS-SDVGQLTCIANNKYG--SDSCVLTLEM-----AVAPTFETIMEDLDVN 1359 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 T + V PVP I WY+ + ++S S T +D LV+ N ++ DSG Y Sbjct: 1360 VGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQAD-DSGVYT 1418 Query: 906 CVASNSAGKSSHGARVTIDVEK 927 C A N AG S A +T+ K Sbjct: 1419 CTAKNLAGSVSCKAELTVHTSK 1440 Score = 71.7 bits (168), Expect = 2e-10 Identities = 41/169 (24%), Positives = 83/169 (49%), Gaps = 5/169 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G+P P + W+ NG ++++ ++ +T + ++ + +H Y Sbjct: 1065 GREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLVVRCVCHAHGGVYKCV 1124 Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702 SN G ++ L V D P P+G ++ I+ +++T+ WK P D ++ + YA Sbjct: 1125 ISNKVGKATCYSHLYVTDILPDPPDGAPVVESITGKTITLSWKKPKRLDPSIDPSSLMYA 1184 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 I++ + +W +A + TY I L++ Y FRV++ FS+ Sbjct: 1185 IQQQALGSIQWTIIASCLKQT-TYTISNLSKGVRYAFRVLSITSKAFSK 1232 Score = 68.9 bits (161), Expect = 1e-09 Identities = 78/301 (25%), Positives = 121/301 (40%), Gaps = 66/301 (21%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582 G T FEC V G + W +I+P+ + +M++D L++ V +D+GT+T Sbjct: 843 GETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKR-CRLLLNSVHEDDSGTYT 901 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C +++ EL A L ++ I P F++K Sbjct: 902 CK------LSTAKEELTSSAKLK----------------------VIASIEPLFTRKLDV 933 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 V EG + +C++ P P + W + +E+I + E H L I++V Sbjct: 934 LEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHS----LIISHVSN 989 Query: 703 FQEGTYTVVAVNREGE----ASL-------PIVLKIKTGEKEP-----PQV--------- 737 EG YTV A N GE A L I +I EK P P+V Sbjct: 990 EDEGLYTVAARNSHGEDECAAELYVQEPRPAISSQIAKLEKMPSIPEEPEVPENEIERFT 1049 Query: 738 ----IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 ++PL M V +G +L +V G P PTITW N K + + + D HS+ Sbjct: 1050 MPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFHNGKRIDSTEDRKMTQFRDVHSLV 1109 Query: 791 I 791 + Sbjct: 1110 V 1110 Score = 67.7 bits (158), Expect = 3e-09 Identities = 35/96 (36%), Positives = 48/96 (50%), Gaps = 1/96 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E ++AP F + G T +F VEG P P I W++ ++ S F Y DDN Sbjct: 1342 EMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVY-DDN 1400 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +LV+ +D+G +TC AKN AG S EL V Sbjct: 1401 ECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436 Score = 61.7 bits (143), Expect = 2e-07 Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 9/203 (4%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKP 794 +I P++ ++V+ GE+ + V+G + W + K ++ L K D +L Sbjct: 831 IIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGKLIQPALLNCKMHFDGKRCRLLLN 890 Query: 795 KKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 +D+ G YT K ++ +SA + V E PLF + + V E + Sbjct: 891 SVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIE-----PLFTRKLDVLEVIEGRNARFD 945 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +V+ P P + W + + +E I +G L+I++V +E D G Y A NS G Sbjct: 946 CKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHVSNE-DEGLYTVAARNSHG 1004 Query: 914 KSSHGARVTIDVEKVTFVKHLQK 936 + A + + + + K Sbjct: 1005 EDECAAELYVQEPRPAISSQIAK 1027 Score = 58.8 bits (136), Expect = 2e-06 Identities = 53/210 (25%), Positives = 97/210 (46%), Gaps = 14/210 (6%) Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGE 1054 ++KCI+K + + + E IR ++D VK + A+ E I + DV W DG+ Sbjct: 811 LLKCIIKQGQVARPV---EPGLAIIRPVRDVMVKAGETALFECHVIGPQDTDVDWLSDGK 867 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDE-SCTAEVTVV-ELPPEI 1109 +I+P G +L + + D G Y+C L ++E + +A++ V+ + P Sbjct: 868 LIQPALLNCKMHFDGKRCRLLLNSVHEDDSGTYTCKLSTAKEELTSSAKLKVIASIEPLF 927 Query: 1110 ITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 +L +V +G A F+ +++ V W ++ + I++ +G + L I Sbjct: 928 TRKLDVLEVIEGRNARFDCKVSGTPPPQVIWSHFDRPLEENEDIRILKEGGRHSLIISHV 987 Query: 1169 DLDDAGEYSCEVGNS----KCTAILTVEEP 1194 +D G Y+ NS +C A L V+EP Sbjct: 988 SNEDEGLYTVAARNSHGEDECAAELYVQEP 1017 Score = 56.8 bits (131), Expect = 6e-06 Identities = 48/213 (22%), Positives = 86/213 (40%), Gaps = 6/213 (2%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSA 1343 +FPP R++ + G VTL P P+ W+ + K ++ + S Sbjct: 2616 DFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQ 2675 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L I K DAG+Y+ N V++ P+ PG P + + ++ + W Sbjct: 2676 LLMIMKTTKKDAGLYECVAANPLATVTSSCVVSLARLPNSPGTPEVPQKYKNTALVVWRP 2735 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 + T T Y +E + W+ V + ++ +L +SYRFR VN+ Sbjct: 2736 SDTTAPCT---YSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQG 2792 Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 S +E V+ T+ Q + +K +++ P Sbjct: 2793 PYSSLSEVV-VLDSTEPQKSSGTVVVKTLSSAP 2824 Score = 56.0 bits (129), Expect = 1e-05 Identities = 40/121 (33%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Query: 491 KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 K++K+P E P +E E+ P FV+ L +G C+V G P P ITWF Sbjct: 1027 KLEKMPSIPEEPEVPENEIERFTMPDFVKPLYDMDVVEGREAVLRCKVAGLPYPTITWFH 1086 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 I ++D +M D V +LV+R V G + CV N G A+ + L V L Sbjct: 1087 NGKRIDSTEDRKMTQFRD-VHSLVVRCVCHAHGGVYKCVISNKVGKATCYSHLYVTDILP 1145 Query: 606 D 606 D Sbjct: 1146 D 1146 Score = 48.8 bits (111), Expect = 0.002 Identities = 29/112 (25%), Positives = 44/112 (39%) Query: 484 LQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW 543 L + +K P + E P+F KLR +G V C G P P I+W Sbjct: 2593 LTRGKKDKTVSQPDIPASIARENDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISW 2652 Query: 544 FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 + ++ M D L+I + +DAG + CVA N +S+ Sbjct: 2653 MKDKKPLEIDPRMNMISCPDGRQLLMIMKTTKKDAGLYECVAANPLATVTSS 2704 Score = 48.4 bits (110), Expect = 0.002 Identities = 41/192 (21%), Positives = 81/192 (42%), Gaps = 15/192 (7%) Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNH---IQLT 1155 E V+ P+I+ ++ Q ++ + L +A V W + G + SN +L+ Sbjct: 1251 EAPVIIDKPDIVYMVEKQPLS------ITVTLNHVNASVTWKRGG--VTLSNRPGLFELS 1302 Query: 1156 I-DGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVEEP-SINFTLRLPEFILVPAN 1211 + D + LK+ D G+ +C N + +LT+E + F + + + Sbjct: 1303 MPDDDQHTLKLCKVKSSDVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGE 1362 Query: 1212 TDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 T + V D+ WYK +++ ++ FT + D + +L++ DD YTC Sbjct: 1363 TPRFAVVVEGKPVPDILWYKGDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAK 1422 Query: 1272 DAKSTTKLKVEV 1283 + + K E+ Sbjct: 1423 NLAGSVSCKAEL 1434 Score = 45.6 bits (103), Expect = 0.015 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 PP L+ ++ +G+ V LS G+P P I+W K+ KP++ P S D + Sbjct: 2618 PPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLL 2677 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++ KD G+Y A N +S V+++ Sbjct: 2678 MIMKTTKKDAGLYECVAANPLATVTSSCVVSL 2709 Score = 45.6 bits (103), Expect = 0.015 Identities = 45/208 (21%), Positives = 82/208 (39%), Gaps = 15/208 (7%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536 P L++ + + L+C+ G P P ++W +D K L+ + + R Sbjct: 2619 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHISWMKDKKPLEIDPRMNMISCPDGRQLLM 2678 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y+C+A N V +SCVV + + P + ++ QK+K +V Sbjct: 2679 IMKTTKKDAGLYECVAANPLATVTSSCVVSLARLP-NSPGTPEVPQKYK-NTALVVWRPS 2736 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTIEASNTAG--- 1652 + P Y K E + + I T + +L S ++ + N AG Sbjct: 2737 DTTAP---CTYSLERKTEGENNWLIVATGVADCYYNVLDLPAGASYRFRVACVNKAGQGP 2793 Query: 1653 -TSSVEVTLKVYDKPSKPEGPVIMREIS 1679 +S EV + +P K G V+++ +S Sbjct: 2794 YSSLSEVVVLDSTEPQKSSGTVVVKTLS 2821 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 9/118 (7%) Query: 993 DVGVIKCIVKDQ--ETSTMLVVKETI-PEFIRKLQDFEVKEKDVAILEVEINSETA-DVV 1048 DVG + CI ++ S +L ++ + P F ++D +V + V + + D++ Sbjct: 1320 DVGQLTCIANNKYGSDSCVLTLEMAVAPTFETIMEDLDVNVGETPRFAVVVEGKPVPDIL 1379 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102 W + G+ + + + + F + L + NT D G Y+C ++ SC AE+TV Sbjct: 1380 WYK-GDTLLSESSHFTFVYDDNECSLVVLNTQADDSGVYTCTAKNLAGSVSCKAELTV 1436 >UniRef50_UPI0000F2138A Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 667 Score = 112 bits (270), Expect = 9e-23 Identities = 136/663 (20%), Positives = 253/663 (38%), Gaps = 63/663 (9%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVI 892 P F+ R + ++ L + NPVP +TW + IS DG+ L I Sbjct: 10 PRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTI 69 Query: 893 TNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK---HLQKSYETEEGK--TVI 947 ++ E DSG Y C A N+ G++ + + + + + + K T G V Sbjct: 70 YDLTLE-DSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPVSTRVGLGGDVT 128 Query: 948 LECQTS-HTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE 1005 C+ S H W + + + + +I E D G C V++ Sbjct: 129 FYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRSLDSGTYNCRVQNS- 187 Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDF 1065 + ++ + LQD +L + ++ + +R E+ + F Sbjct: 188 ----IGRAQSAATLVVDLQDTH-------LLNADKSTSLLSHMQKRKQEM----RTDISF 232 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKAT 1125 + +T + +E + RD+ LP + TR V +G A Sbjct: 233 YRTTESSSTTSSSTKITEEHGSFGLARDQEQRVSALTSMLPKGVFTRTCT--VTEGKHAK 290 Query: 1126 FEIELT-KGDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN- 1182 +T + W KDG+ I + H+ + LK+ C D G Y+C N Sbjct: 291 LSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYTCNASNL 350 Query: 1183 -----------------------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 ++ + + V++P I F +L + + V A L E Sbjct: 351 AGQTYSAVLVIVKGTLEKGHRNLAEYQSTIAVQKPKIPFKKKLQD-VEVKEKETATLQCE 409 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL 1279 +P +W+ +++ +E K+ + + R L IR T +D Y C + + T Sbjct: 410 VPVSNTKASWFMEETRLEQNTKYRMDEEGTLRRLTIRNVTTNDDAVYICEMNEGSRTVAE 469 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 + K+ R + V V+ + P + W N + +K+ + Sbjct: 470 LTVLGNITKKL---PRRTVVPVSDTVIFCVELEK-PVDDAYWTRNGERLKEDSRIIIARV 525 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--PSPPGKPNILEIDSSSI 1397 ++ +LTI++ D+G + ++C +VT K P PP +P + SSI Sbjct: 526 NRQYTLTIRECTAEDSGEVAF-IAHDC-KTSTRFSVTAPRKHPPDPPVEPIVQNKTDSSI 583 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYA 1455 +CW P++ I Y+VE +++ T W+ + ++ T+ +I ++ +SY+FR A Sbjct: 584 TLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTKYTITDVLEETSYQFRISA 643 Query: 1456 VNE 1458 VN+ Sbjct: 644 VND 646 Score = 89.8 bits (213), Expect = 7e-16 Identities = 63/236 (26%), Positives = 108/236 (45%), Gaps = 16/236 (6%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P+ + K+ + G LS +VGNP P +TW K + A T DGD + +TI Sbjct: 10 PRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTI 69 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 ++D G Y +A+N+ G A + + V P P+FI + V G + Sbjct: 70 YD-LTLEDSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPVSTRVGLGGDVT 128 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNS 911 RV+ +P P+ W ++ + + I + ++ L I +V S +DSG Y C NS Sbjct: 129 FYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRS-LDSGTYNCRVQNS 187 Query: 912 AGKSSHGARVTIDVE---------KVTFVKHLQKSYETEEGKTVILECQTSHTVST 958 G++ A + +D++ + + H+QK +E +T I +T+ + ST Sbjct: 188 IGRAQSAATLVVDLQDTHLLNADKSTSLLSHMQK--RKQEMRTDISFYRTTESSST 241 Score = 71.3 bits (167), Expect = 3e-10 Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 1/155 (0%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P + W +NG +L+ D I + + I+E S + A + ++ VT Sbjct: 501 PVDDAYWTRNGERLKEDSRIIIARVNRQYTLTIRECTAEDSGEVAFIAHDCKTSTRFSVT 560 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 P P P++ + S+T+ W PP + + +T Y +E+ + W+K+ Sbjct: 561 APRKHPPDPPVEPIVQNKTD-SSITLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTT 619 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE 1754 Y I + E Y FR+ A N G S LE Sbjct: 620 PVSTTKYTITDVLEETSYQFRISAVNDFGQSAYLE 654 Score = 65.7 bits (153), Expect = 1e-08 Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 13/202 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L G P F +PKA + G D L C +V P P + W + I + D+ Sbjct: 5 LFGGAPRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDI 64 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI----KTGEKEPPQVIEPLKSM 744 + L I ++ G Y A N GEA + LK+ E+ P +++P+ S Sbjct: 65 YR----LTIYDLTLEDSGQYMCRAKNTVGEAYAAVTLKVGLPETVVERAPVFIVKPV-ST 119 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKDEG 801 V G V +V +P P W K+ + + S+ D+ S+ I + + D G Sbjct: 120 RVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDSSSLRIQSVRSL-DSG 178 Query: 802 VYTLKAENSEGIAETSAVITVE 823 Y + +NS G A+++A + V+ Sbjct: 179 TYNCRVQNSIGRAQSAATLVVD 200 Score = 65.7 bits (153), Expect = 1e-08 Identities = 33/85 (38%), Positives = 46/85 (54%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 PP P +V T S+TL W+ P+S PIT YI+E + V ++W KI T S + Sbjct: 566 PPDPPVEPIVQNKTDSSITLCWSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTK 625 Query: 1925 HCIENIKEKDEIIFRISAENTVGVS 1949 + I ++ E+ FRISA N G S Sbjct: 626 YTITDVLEETSYQFRISAVNDFGQS 650 Score = 64.9 bits (151), Expect = 2e-08 Identities = 59/219 (26%), Positives = 83/219 (37%), Gaps = 28/219 (12%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP F+ + + G C + G P P +TW ++ I F+ D D + L Sbjct: 9 APRFLTRPKAFSLCVGRDASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGD-IYRL 67 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I ++ ED+G + C AKN G A + L V P E V Sbjct: 68 TIYDLTLEDSGQYMCRAKNTVGEAYAAVTLKVGLP------ETVVERA------------ 109 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 P F KP + V G D+ CR+ A P P+ W G + I + ESD Sbjct: 110 -----PVFIVKPVSTRVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESD- 163 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 S L+I +V+ GTY N G A L + Sbjct: 164 ---SSSLRIQSVRSLDSGTYNCRVQNSIGRAQSAATLVV 199 Score = 57.2 bits (132), Expect = 5e-06 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP P+ S+I + W P+ + P+ GY + R V W+++ V+T K Sbjct: 567 PDPPVEPIVQNKTDSSITLC-WSPPDSERPVPITGYIVERRKVGTQTWVKITTTPVSTTK 625 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + I D+ E +Y RI A N+ G S LE Sbjct: 626 YTITDVLEETSYQFRISAVNDFGQSAYLE 654 Score = 50.0 bits (114), Expect = 7e-04 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 1/93 (1%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F+ K G V F C+V +P P W + + + ++ + D+ ++L Sbjct: 109 APVFIVKPVSTRVGLGGDVTFYCRVSAHPAPNFDWEKDGRYLGETNRIKITSESDS-SSL 167 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I+ V D+GT+ C +N+ G A S L+V+ Sbjct: 168 RIQSVRSLDSGTYNCRVQNSIGRAQSAATLVVD 200 Score = 47.2 bits (107), Expect = 0.005 Identities = 26/82 (31%), Positives = 36/82 (43%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G + C V G+P+PQI W + I + MY D L + D G +T Sbjct: 285 EGKHAKLSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYT 344 Query: 583 CVAKNAAGFASSTTELIVEAPL 604 C A N AG S +IV+ L Sbjct: 345 CNASNLAGQTYSAVLVIVKGTL 366 Score = 45.2 bits (102), Expect = 0.020 Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 13/176 (7%) Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXXXXXX--YKCIAF 1553 D L+C G P P VTW ++ ++ T E+ Y C A Sbjct: 26 DASLSCTIVGNPVPVVTWEKEKLRISAGGRFKTVEDGDIYRLTIYDLTLEDSGQYMCRAK 85 Query: 1554 NDHGEVETSCV--VG-----IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 N GE + VG +++ PV + + + + +G + + P P W Sbjct: 86 NTVGEAYAAVTLKVGLPETVVERAPVFIV--KPVSTRVGLGGDVTFYCRVSAHPAPNFDW 143 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 K+G L IT++ +S +RI+ ++ S Y N+ G + TL V Sbjct: 144 EKDGRYLGETNRIKITSESDSSSLRIQSVRSLDSGTYNCRVQNSIGRAQSAATLVV 199 Score = 37.5 bits (83), Expect = 4.0 Identities = 20/73 (27%), Positives = 39/73 (53%), Gaps = 3/73 (4%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 ++ + G P P+++W K+G + E + + + ++++ K+S + YT ASN Sbjct: 291 LSCFVTGHPKPQIMWRKDGTNISEGRRHVMYEDQAENFILKVLYCKQSDNGLYTCNASNL 350 Query: 1651 AGT--SSVEVTLK 1661 AG S+V V +K Sbjct: 351 AGQTYSAVLVIVK 363 >UniRef50_UPI0000D5788D Cluster: PREDICTED: similar to CG31738-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG31738-PB, isoform B - Tribolium castaneum Length = 965 Score = 112 bits (270), Expect = 9e-23 Identities = 103/412 (25%), Positives = 172/412 (41%), Gaps = 31/412 (7%) Query: 1642 KYTIEASNTAGTS--SVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 K+ + A N G S S EVT + D+P +P PV+ I S ++W+PP GG ++ Sbjct: 312 KFRLRAENDGGQSPWSDEVTYQTLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADI 371 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 T+Y + E ++ +V + E C KL Y R + G S S P Sbjct: 372 TEYIL---EVNSGSGYEVVYTGTETEAVC-DKLTPGTTYQLRASCISAGGRSN--YSNPC 425 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWK-XXX 1817 + T P + S+ I W + NGG+P+++Y+VE+ + Sbjct: 426 TVTTDAIAPGQCAAPRLHGKPKSSSITIRWCEPDYNGGAPVLEYEVEMAGPPDHTRNLVH 485 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 L+ Y+F + A N IG L ++ K+T G PP + Sbjct: 486 KSKETECTAANLTPGCEYEFFVRAVNRIGPGL-WSDPLKVTSG--AAPPDVIETLATNCK 542 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 + + ++W EP SN G+PI +Y +E T + G+ + H ++ + Sbjct: 543 SPFHIFVEWREPPSN-GAPILDYRLEISTSNNDFH---LVYQGAENYHDVKGLSPFTTYY 598 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGA 1996 FR+ A N+ G SL + + T +PP++ +R + +T +W P + G+ Sbjct: 599 FRVQACNSAGCSLYSPVAAT-----VTPAAPPSSVTTLRSDSTPTSITLNWNEPS-NNGS 652 Query: 1997 PLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + YNI D ++ D ++ I +L TY I+I A N IG Sbjct: 653 EITHYNIEFGD-------KLIVTDGPVREYQIDNLQPETTYKIKIQAVNAIG 697 Score = 54.4 bits (125), Expect = 3e-05 Identities = 60/244 (24%), Positives = 95/244 (38%), Gaps = 20/244 (8%) Query: 1606 WYKNGNKLENDKEYNITTKEKTSVI-------RIKELKRSHSSKYTIEASNTAGTSSVEV 1658 W + N YNI +K V +I L+ + K I+A N GT S+ Sbjct: 644 WNEPSNNGSEITHYNIEFGDKLIVTDGPVREYQIDNLQPETTYKIKIQAVNAIGTGSLSS 703 Query: 1659 TLKVYDKPSKPEGPVI-MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA 1717 TLKV P P + I + ++W D ++ T Y IE +N R Sbjct: 704 TLKVSTLKLPPAAPRLECIGIGHNYLKLKWG---DGKNVDYTHYLIEM---ENGRTHDFQ 757 Query: 1718 DVDRDVE-TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXX 1776 V + TY + KL+E Y FR+ A N G + S+ T++ P Sbjct: 758 CVYKGTALTYKVNKLHELTTYRFRICASNDAGVGDF--SDIYEFTTSI-APPAVVKQPKL 814 Query: 1777 XXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXXXXXARIQKLSINTTY 1835 +D S I W PS+ P+I ++V++ + + + +K I+ L Y Sbjct: 815 IEVDQTSCVIEWMPSKNQFVDPVI-FQVQVARVKDQFFKETYRGAESKCSIENLESGVEY 873 Query: 1836 QFRI 1839 R+ Sbjct: 874 SARV 877 Score = 52.8 bits (121), Expect = 1e-04 Identities = 58/225 (25%), Positives = 93/225 (41%), Gaps = 17/225 (7%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 S+ + W S + GS I Y +E + +G + I KL T Y+FR+ A Sbjct: 169 SLQLKW-NSVNDNGSHITCYILEYDEGKGGDFVEFHRGRVKQYTIHKLQPATPYRFRLAA 227 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 NEIG S Y+ + +T PP++P V++E++ + L+W++ S+ Sbjct: 228 MNEIGKS-GYS--EVVTYNTCNNPPTKPPPPVLAEASINYLHLQWSKRPSDE-------- 276 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCI-ENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 EF S T V CI + E FR+ AEN G S S V + Sbjct: 277 -EFTLQMNDSRTSYRPVYNGRETICICTGLSNFTEYKFRLRAENDGGQS--PWSDEVTYQ 333 Query: 1961 KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005 P P+ P+ + ++ W P + GGA + Y + + Sbjct: 334 TLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADITEYILEV 378 Score = 52.0 bits (119), Expect = 2e-04 Identities = 78/336 (23%), Positives = 124/336 (36%), Gaps = 26/336 (7%) Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 D N+ K K + L ++ + A N G LKV + P+ + Sbjct: 478 DHTRNLVHKSKETECTAANLTPGCEYEFFVRAVNRIGPGLWSDPLKVTSGAAPPDVIETL 537 Query: 1676 REISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLN 1732 + + +EW+ P +G + Y +E +N+ + V + E Y ++ L+ Sbjct: 538 ATNCKSPFHIFVEWREPPSNGA-PILDYRLEISTSNNDFHL----VYQGAENYHDVKGLS 592 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 Y FRV A N G S L S T PS S+ + W Sbjct: 593 PFTTYYFRVQACNSAGCS--LYSPVAATVTPAAPPSSVTTLRSDST--PTSITLNW-NEP 647 Query: 1793 KNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYT 1852 N GS I Y +E G K +I L TTY+ +I A N IGT + Sbjct: 648 SNNGSEITHYNIEF---GDKL-IVTDGPVREYQIDNLQPETTYKIKIQAVNAIGTG---S 700 Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW 1912 + + PP+ PR + + LKW + ++ T+Y+IE + G++ Sbjct: 701 LSSTLKVSTLKLPPAAPRLECIGIG-HNYLKLKWGDGKN---VDYTHYLIEME--NGRTH 754 Query: 1913 TKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 G+ + + + E FRI A N GV Sbjct: 755 DFQCVYKGTALTYKVNKLHELTTYRFRICASNDAGV 790 Score = 47.2 bits (107), Expect = 0.005 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 +P P P + + +S+ + W+ + G S I Y++EY E +++ Q + Sbjct: 153 EPDQPQPPKLHQRQKTSLQLKWNSVNDNG-SHITCYILEYDEGKGGDFVEFHRGRVKQYT 211 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 I L+ + YRFR A+NE+ S SE Y Sbjct: 212 IHKLQPATPYRFRLAAMNEIGKSGYSEVVTY 242 Score = 46.8 bits (106), Expect = 0.007 Identities = 43/173 (24%), Positives = 71/173 (41%), Gaps = 13/173 (7%) Query: 1802 YKVEIKQEGK--KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 Y+V + + K K+K RI+ L Y + + L + D + Sbjct: 91 YEVLLSDKSKEMKFKSIYSGTSLSCRIRDLKPGQEYSVCLQVHYD---ELQGAATDPVKF 147 Query: 1860 GKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVG 1919 P QP+ + + S+ LKW N GS IT YI+E+ KG + + Sbjct: 148 TTPPCEPDQPQPPKLHQRQKTSLQLKWNSVNDN-GSHITCYILEYDEGKGGDFVEFHR-- 204 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAP 1972 G V ++ I ++ FR++A N +G S +E + + T +PPT P Sbjct: 205 GRVKQYTIHKLQPATPYRFRLAAMNEIGKSGYSE-----VVTYNTCNNPPTKP 252 Score = 43.2 bits (97), Expect = 0.081 Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 6/104 (5%) Query: 1358 YKLRLENNCGHADVEMNVT---ILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTII 1413 ++LR EN+ G + VT + D+P P KP + I + S + W+ P TG + I Sbjct: 313 FRLRAENDGGQSPWSDEVTYQTLPDRPREPSKPVVKGRIHAHSFKLKWEPPNYTGGADIT 372 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 Y++E E V T+T+ L ++Y+ RA ++ Sbjct: 373 EYILEVNSGSGYE--VVYTGTETEAVCDKLTPGTTYQLRASCIS 414 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 8/88 (9%) Query: 1382 SPPGKPNILEIDSS--SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS 1439 +PP L DS+ SI + W+EP N G S I +Y +E+ + + V + + Sbjct: 623 APPSSVTTLRSDSTPTSITLNWNEPSNNG-SEITHYNIEF-----GDKLIVTDGPVREYQ 676 Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASET 1467 I NL+ ++Y+ + AVN + S T Sbjct: 677 IDNLQPETTYKIKIQAVNAIGTGSLSST 704 Score = 39.5 bits (88), Expect = 0.99 Identities = 32/141 (22%), Positives = 61/141 (43%), Gaps = 12/141 (8%) Query: 1358 YKLRLE--NNCGHADVEMNVTILDKPSPPGKPNI--LEIDSSSINICWDEPENTGNSTII 1413 YK++++ N G + + + PP P + + I + + + W + +N + Sbjct: 686 YKIKIQAVNAIGTGSLSSTLKVSTLKLPPAAPRLECIGIGHNYLKLKWGDGKNVDYT--- 742 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +Y++E + T ++ V T + L ++YRFR A N+ + D S+ E+ Sbjct: 743 HYLIEMENGRTHDFQCVYKGTALTYKVNKLHELTTYRFRICASNDAGVGDFSDIYEF--- 799 Query: 1474 IKETKIQSPTVEKPLKNITTE 1494 T I P V K K I + Sbjct: 800 --TTSIAPPAVVKQPKLIEVD 818 >UniRef50_UPI0000E4A8AD Cluster: PREDICTED: similar to Ptprd protein, partial; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Ptprd protein, partial - Strongylocentrotus purpuratus Length = 1773 Score = 112 bits (269), Expect = 1e-22 Identities = 126/537 (23%), Positives = 213/537 (39%), Gaps = 36/537 (6%) Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXX 1546 P + + E N + C G P+P++ W+++ ++ Sbjct: 76 PRRYMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRISMTDSGLQFSRAQLSDQG 135 Query: 1547 XYKCIAFNDHG---EVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 Y+C A N G VE V +Q +P TI E+ Q+ G +T G P P Sbjct: 136 RYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPEN--QEVVPGGSVNLTCAAYGSPMP 193 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 V W K G L++ + I +V++++++ S+ YT A++ GT + V Sbjct: 194 RVRWMKAGMDLDDMDDLPI----GRNVLQLRDI--YESANYTCVATSLLGTIDTSARVTV 247 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE-KHEPDNNRWIKVADVDR 1721 +PS P PV+ S S+T+EW D +T + +E K + ++ Sbjct: 248 RTRPSVPNSPVVTGYTS-SSLTVEWSTLSSD---TVTSHVLEYKRSRSGGSFTEMEIPSP 303 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 ++ I+ L EY R++A N +G S S+ + T DVPS I Sbjct: 304 QDTSFTIEGLLPYTEYAVRLLAVNSIGRSN--PSDEVTAMTGEDVPS-QPEQFEGVAISA 360 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIK-QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 + +TW + II Y++ + L NT Y R+ Sbjct: 361 SQIRLTWMMRDTE--PQIIRYELYYNVSTNDNDMHKTITPTTDYVLDNLRPNTLYHIRLA 418 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVV-SESTSRSVTLKWTEP--ESNGGSPI 1897 AR+E G S IT+ + P P V + +S S+ ++W+ P E G I Sbjct: 419 ARSETGEG---ASSPVITVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGD-I 474 Query: 1898 TNYIIEFK---TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 T Y I ++ V + V V V + +E +++ R+ A +G P++S Sbjct: 475 TGYKIIYRKMSLVSTNNPEMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPPSDS 534 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTK 2010 S+R + A P P + +R+ S + W P+ D + GY I + VT+ Sbjct: 535 LSIRTAEDA--PEGPPRKVRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTVTE 589 Score = 70.9 bits (166), Expect = 4e-10 Identities = 114/517 (22%), Positives = 191/517 (36%), Gaps = 40/517 (7%) Query: 1407 TGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 TGN I + E+ I+ + IS+ T + + + R+ A N + + Sbjct: 95 TGNPEPEILWFKEFVPIEANDRISM---TDSGLQFSRAQLSDQGRYECAAKNSLGTRYSV 151 Query: 1466 ETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA 1525 E Y +K+ +++ P +N P + LTC G P P+V W + G L Sbjct: 152 EAQVY---VKDRQVEPRFTILP-ENQEVVPGGSVNLTCAAYGSPMPRVRWMKAGMDLDDM 207 Query: 1526 KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK 1585 R Y C+A + G ++TS V ++ +P ++ N + + Sbjct: 208 DDLPIGR--NVLQLRDIYESANYTCVATSLLGTIDTSARVTVRTRP--SVPNSPVVTGYT 263 Query: 1586 VGD---EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 EW + + V+ YK + E I + + TS I+ L Sbjct: 264 SSSLTVEW--STLSSDTVTSHVLEYKRSRSGGSFTEMEIPSPQDTS-FTIEGLLPYTEYA 320 Query: 1643 YTIEASNTAGTS--SVEVT-LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT 1699 + A N+ G S S EVT + D PS+PE IS + + W + D ++ Sbjct: 321 VRLLAVNSIGRSNPSDEVTAMTGEDVPSQPE-QFEGVAISASQIRLTWM--MRDTEPQII 377 Query: 1700 KYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 +Y + + N N K D Y + L N Y R+ A++ G E S I Sbjct: 378 RYELYYNVSTNDNDMHKTITPTTD---YVLDNLRPNTLYHIRLAARSETG--EGASSPVI 432 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNG---GSPIIDYKVE-IKQEGK 1811 ++T P + + S+ + W P ++NG G II K+ + Sbjct: 433 TVRTQQSAPGAPPQEVSGTVLSSTSIEVRWSPPPLEDQNGDITGYKIIYRKMSLVSTNNP 492 Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + ++ L T Y R+ A IG P SD P PR Sbjct: 493 EMNVPVEADVRSYILEALRKYTLYDIRVVACTAIGDGPP--SDSLSIRTAEDAPEGPPRK 550 Query: 1872 FVVSESTSRSVTLKWTEPESN-GGSPITNYIIEFKTV 1907 V S ++ ++W P+ + I Y I+++TV Sbjct: 551 VRVRVHNSTTIRVQWQAPDPDLQNGEIRGYRIDYQTV 587 Score = 55.6 bits (128), Expect = 1e-05 Identities = 55/230 (23%), Positives = 90/230 (39%), Gaps = 16/230 (6%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 P P + M+V + GNP P I W K P++A S T S Sbjct: 70 PEITSNPRRYMVVENNRPATIYCGATGNPEPEILWFKEFVPIEANDRIS--MTDSGLQFS 127 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 ++ D+G Y A+NS G T + + ++ P F + V G++ L Sbjct: 128 RAQLSDQGRYECAAKNSLG---TRYSVEAQVYVKDRQVEPRFTILPENQEVVPGGSVNLT 184 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +P+P + W + + + + G N+ L + ++ +S +Y CVA++ G Sbjct: 185 CAAYGSPMPRVRWMKAGMDLDDMDDLP---IGRNV-LQLRDI---YESANYTCVATSLLG 237 Query: 914 KSSHGARVTI----DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959 ARVT+ V V S T E T+ + TSH + K Sbjct: 238 TIDTSARVTVRTRPSVPNSPVVTGYTSSSLTVEWSTLSSDTVTSHVLEYK 287 Score = 53.6 bits (123), Expect = 6e-05 Identities = 57/207 (27%), Positives = 94/207 (45%), Gaps = 16/207 (7%) Query: 1845 IGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 + TSL T D + T PS P + VV+ TS S+T++W+ S+ +T++++E+ Sbjct: 231 VATSLLGTIDTSARV-TVRTRPSVPNSPVVTGYTSSSLTVEWSTLSSD---TVTSHVLEY 286 Query: 1905 KTVK-GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 K + G S+T++ IE + E R+ A N++G S P S V Sbjct: 287 KRSRSGGSFTEMEIPSPQDTSFTIEGLLPYTEYAVRLLAVNSIGRSNP--SDEVTAMTGE 344 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPL--LGYNIAIRDVTKTMWMEVGKVDV 2021 VPS P + + S I +T W + + L YN++ D ++ K Sbjct: 345 DVPSQPEQFEGVAISASQIRLT-WMMRDTEPQIIRYELYYNVSTND------NDMHKTIT 397 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIG 2048 T + + +L N Y IR+ AR+E G Sbjct: 398 PTTDYVLDNLRPNTLYHIRLAARSETG 424 Score = 52.4 bits (120), Expect = 1e-04 Identities = 52/202 (25%), Positives = 82/202 (40%), Gaps = 15/202 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G P S + V+ + C PEP+I W FK E VP + + M Sbjct: 68 GYPEITSNPRRYMVVENNRPATIYCGATGNPEPEILW-FK--EFVP-----IEANDRISM 119 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 S L+ + + +G Y A N G S+ + +K + EP I P +V G Sbjct: 120 TDSGLQFSRAQLSDQGRYECAAKNSLGTRYSVEAQVYVKDRQVEPRFTILPENQEVV-PG 178 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 SV L+ G+P P + W K + + G +L+ + + + YT A + Sbjct: 179 GSVNLTCAAYGSPMPRVRWMKAGMDLDDMDDLPIGR----NVLQLRDIYESANYTCVATS 234 Query: 810 SEGIAETSAVITVE-EPTEENA 830 G +TSA +TV P+ N+ Sbjct: 235 LLGTIDTSARVTVRTRPSVPNS 256 Score = 44.8 bits (101), Expect = 0.026 Identities = 60/284 (21%), Positives = 104/284 (36%), Gaps = 21/284 (7%) Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP--VIMREISRESVTIEWKPPL 1691 +L+ ++ + ASN G S+ + + + P V +S S+++ W PPL Sbjct: 710 DLRLGTRYEFKLTASNEEGNSNEAIFYYTTHEGTPSGSPMNVTASPLSSSSISVSWDPPL 769 Query: 1692 DD--GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGF 1749 ++ GL L KY I + + + D+ + L N Y V A VG Sbjct: 770 EEERNGLIL-KYTIRYYSSAMPTELTNRTTETDI---VLTSLVPNTAYSVEVRAHTSVG- 824 Query: 1750 SEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGGSPIIDYKVEIKQ 1808 S + T + P+ + + W PS P +Y V Sbjct: 825 -PGPYSTKDIATTPREAPASAPLDLRCAAPHGTQLEVKWSHPSNIQRSGPGYNYLVYSTN 883 Query: 1809 EGKK-----W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 W + ++ L TTY + G S P + IT Sbjct: 884 SADNTDVSTWGRPVSAGEFTKLELRGLQEETTYYVAVKLDTPEGNS-PLSQI--ITCLTG 940 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 + PS+PR+F ++ ++ L W+EP G + +Y+I++ T Sbjct: 941 TSAPSEPRSFDAHIASDNTINLVWSEPSDIPGR-LKDYVIKYHT 983 Score = 43.6 bits (98), Expect = 0.061 Identities = 49/251 (19%), Positives = 95/251 (37%), Gaps = 25/251 (9%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKST-----TKLK 1280 ++ W+K+ IE ++ ++ L + DQ Y C ++ T ++ Sbjct: 101 EILWFKEFVPIEANDRISMTDS----GLQFSRAQLSDQGRYECAAKNSLGTRYSVEAQVY 156 Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V+ + P+ + G V L P P W+ K +D Sbjct: 157 VKDRQVEPRFTILPENQEVVPGGSVNLTCAAYGSPMPRVRWM-------KAGMDLDDMDD 209 Query: 1341 KSASLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 + ++ + ++ Y + G D VT+ +PS P P + SSS+ + Sbjct: 210 LPIGRNVLQLRDIYESANYTCVATSLLGTIDTSARVTVRTRPSVPNSPVVTGYTSSSLTV 269 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDT----TEWISVKNITKTQTSIQNLKTNSSYRFRAYA 1455 W + T+ +V+EY+ + TE + + + T +I+ L + Y R A Sbjct: 270 EW---STLSSDTVTSHVLEYKRSRSGGSFTE-MEIPSPQDTSFTIEGLLPYTEYAVRLLA 325 Query: 1456 VNEVDISDASE 1466 VN + S+ S+ Sbjct: 326 VNSIGRSNPSD 336 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 5/106 (4%) Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKP-NILE--IDSSSINICWDEP-ENTGNSTII 1413 +KL N G+++ + + +P G P N+ + SSSI++ WD P E N I+ Sbjct: 719 FKLTASNEEGNSNEAIFYYTTHEGTPSGSPMNVTASPLSSSSISVSWDPPLEEERNGLIL 778 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 Y + Y ++ T+T + +L N++Y A V Sbjct: 779 KYTIRYYSSAMPTELT-NRTTETDIVLTSLVPNTAYSVEVRAHTSV 823 >UniRef50_UPI0000E47894 Cluster: PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to scavenger receptor cysteine-rich protein type 12 precursor - Strongylocentrotus purpuratus Length = 2255 Score = 112 bits (269), Expect = 1e-22 Identities = 89/354 (25%), Positives = 164/354 (46%), Gaps = 27/354 (7%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI---AWLFKGEEIVPDENISVAI 684 ++ PPTF+++PK + ++ GS L C+ P P + +WL G+ + + S + Sbjct: 1772 VVSSYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRL 1831 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSM 744 ++ L+ ++ G YT V N +G + L + KE P ++ Sbjct: 1832 R--VYTSSGSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVV----KERPHIMSTHPDT 1885 Query: 745 IVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 + GE+ L VVG P T++W +N +P+ +S G+ ++ +++ +++D G+Y Sbjct: 1886 RI-LGETAELGCIVVGLPESTVSWRRNGQPLMGERFQSFGENGTL-LIRDVRLEDNGMYE 1943 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N G + S +TV E P F+ QE+ V+ + + V+ P+P I Sbjct: 1944 CVAVNQLGEDQASVKLTV-------YEVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEI 1996 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TW ++ ++IS + +T E+ LVI E D G+Y C+ASN S+ A++ I Sbjct: 1997 TWKKDGQMISLNGRVTIL---EDNTLVIHKSQRE-DMGEYACIASNKVQTSARIAKLLI- 2051 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREII 976 + + G+TV+L C ++ W HN +++ D R ++ Sbjct: 2052 -IGPPHITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVVN-DERHLM 2103 Score = 74.1 bits (174), Expect = 4e-11 Identities = 83/333 (24%), Positives = 135/333 (40%), Gaps = 26/333 (7%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 + SS + V D G+ V +++ P S P + + E ++ Sbjct: 1834 YTSSGSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRILGETAE 1893 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 L C +V +PE ++W G+ ++ + S L I +V+ G Y Sbjct: 1894 --LGCIVVGLPESTVSWRRNGQPLMGERFQSFGENG-------TLLIRDVRLEDNGMYEC 1944 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 VAVN+ GE + L + E P +E + M VR G V + V G P P ITW K Sbjct: 1945 VAVNQLGEDQASVKLTVY----EVPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKK 2000 Query: 771 NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 + + + + + +++ I K ++ +D G Y A N + A + + P Sbjct: 2001 DGQMISLNGRVTILEDNTLVIHKSQR-EDMGEYACIASNKVQTSARIAKLLIIGPPHITE 2059 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P N+ + +T + T+ L V P +TW N E + E D L Sbjct: 2060 APT---NQTR-VTGE---TVVLPCTVIGAYNPVVTWQHNGEDVVNDERHLMVDDS----L 2108 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +T+VD D G Y C A+N+ G S A V+I Sbjct: 2109 TVTDVDPA-DGGLYVCTATNTEGAVSANAYVSI 2140 Score = 70.9 bits (166), Expect = 4e-10 Identities = 45/190 (23%), Positives = 85/190 (44%), Gaps = 6/190 (3%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 E EL CI G+P+ V+W R+G+ L + ++ Y+C+A N Sbjct: 1890 ETAELGCIVVGLPESTVSWRRNGQPLMGERFQSFGENGTLLIRDVRLEDNGMYECVAVNQ 1949 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 GE + S + + + P ++++ + G + + V+ G+P PE+ W K+G + Sbjct: 1950 LGEDQASVKLTVYEVPTFLEGPQEMEV--RTGSDVSIPCVVSGVPLPEITWKKDGQMISL 2007 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 + +T E +++ I + +R +Y ASN TS+ L + P E P Sbjct: 2008 NG--RVTILEDNTLV-IHKSQREDMGEYACIASNKVQTSARIAKLLIIGPPHITEAPTNQ 2064 Query: 1676 REISRESVTI 1685 ++ E+V + Sbjct: 2065 TRVTGETVVL 2074 Score = 66.9 bits (156), Expect = 6e-09 Identities = 62/236 (26%), Positives = 99/236 (41%), Gaps = 16/236 (6%) Query: 591 FASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSD 650 F + T LI + L D+G V + +P TF + P+ V GSD Sbjct: 1923 FGENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTVYEVP-TFLEGPQEMEVRTGSD 1981 Query: 651 ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 + + C + +P P+I W G+ I N V I D + L I ++ G Y Sbjct: 1982 VSIPCVVSGVPLPEITWKKDGQMI--SLNGRVTILED-----NTLVIHKSQREDMGEYAC 2034 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 +A N+ + S I + G PP + E + GE+V+L V+G P +TW Sbjct: 2035 IASNKV-QTSARIAKLLIIG---PPHITEAPTNQTRVTGETVVLPCTVIGAYNPVVTWQH 2090 Query: 771 NNKP-VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 N + V D+ ++T + P D G+Y A N+EG +A +++ P Sbjct: 2091 NGEDVVNDERHLMVDDSLTVTDVDP---ADGGLYVCTATNTEGAVSANAYVSITGP 2143 Score = 64.9 bits (151), Expect = 2e-08 Identities = 69/309 (22%), Positives = 127/309 (41%), Gaps = 23/309 (7%) Query: 1079 TSVHDEGEYSCILRDE---SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 T D G Y+C++R+ + ++ VV+ P I++ + ++ I + ++ Sbjct: 1845 TRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRILGETAELGCIVVGLPES 1904 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTV 1191 V W ++G + G+ L I D L+D G Y C ++G + + LTV Sbjct: 1905 TVSWRRNGQPLMGERFQSF---GENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTV 1961 Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKK 1250 E + L P+ + V +D + + L ++TW K +I + T++ D Sbjct: 1962 YE--VPTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDGQMISLNGRVTILED--- 2016 Query: 1251 RTLIIRKCTEDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 TL+I K +D EY C+ + +++ ++ ++ PP I + G V L Sbjct: 2017 NTLVIHKSQREDMGEYACIASNKVQTSARIAKLLIIGPPHITEAPTNQTRVTGETVVLPC 2076 Query: 1310 DYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 P W N + ++ +H +D SLT+ V+ D G+Y N G Sbjct: 2077 TVIGAYNPVVTWQHNGEDVVNDERHL--MVDD---SLTVTDVDPADGGLYVCTATNTEGA 2131 Query: 1369 ADVEMNVTI 1377 V+I Sbjct: 2132 VSANAYVSI 2140 Score = 60.1 bits (139), Expect = 7e-07 Identities = 48/213 (22%), Positives = 85/213 (39%), Gaps = 15/213 (7%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT---WYRDGKKLKTAKAT------YENR 1532 PT + KN T C G P P+VT W +DG+ L + Y + Sbjct: 1778 PTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVYTSS 1837 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C+ N G +S + ++++P I ++ D + +G+ + Sbjct: 1838 GSLQFVRTRREDSGNYTCVIRNTQGVNTSSAFLVVKERPHIMSTHPDTRI---LGETAEL 1894 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 ++ G+P V W +NG L ++ + + + I++++ + Y A N G Sbjct: 1895 GCIVVGLPESTVSWRRNGQPLMGER---FQSFGENGTLLIRDVRLEDNGMYECVAVNQLG 1951 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 V L VY+ P+ EGP M + V+I Sbjct: 1952 EDQASVKLTVYEVPTFLEGPQEMEVRTGSDVSI 1984 Score = 59.3 bits (137), Expect = 1e-06 Identities = 50/227 (22%), Positives = 90/227 (39%), Gaps = 21/227 (9%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I++++ + + AVN++ AS +K T + PT + + + D+ Sbjct: 1931 IRDVRLEDNGMYECVAVNQLGEDQAS--------VKLTVYEVPTFLEGPQEMEVRTGSDV 1982 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 + C+ GVP P++TW +DG+ + + T Y CIA N + Sbjct: 1983 SIPCVVSGVPLPEITWKKDGQMISLNGRVTILEDNTLVIHKSQREDMGEYACIASN---K 2039 Query: 1559 VETSCVVG---IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 V+TS + I P IT Q G+ ++ + G P V W NG + N Sbjct: 2040 VQTSARIAKLLIIGPPHIT--EAPTNQTRVTGETVVLPCTVIGAYNPVVTWQHNGEDVVN 2097 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 D+ + + T + ++ + Y A+NT G S + + Sbjct: 2098 DERHLMVDDSLT----VTDVDPADGGLYVCTATNTEGAVSANAYVSI 2140 Score = 57.6 bits (133), Expect = 4e-06 Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 20/205 (9%) Query: 993 DVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV 1048 D G C++++ + +S LVVKE P + D + + + + + + V Sbjct: 1849 DSGNYTCVIRNTQGVNTSSAFLVVKER-PHIMSTHPDTRILGETAELGCIVVGLPESTVS 1907 Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI----LRDESCTAEVTVVE 1104 W R+G+ + ++ F+ G L IR+ + D G Y C+ L ++ + ++TV E Sbjct: 1908 WRRNGQPLMGER----FQSFGENGTLLIRDVRLEDNGMYECVAVNQLGEDQASVKLTVYE 1963 Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQK 1162 + P + Q +V G+ + + G L + W KDG I + + + D Sbjct: 1964 V-PTFLEGPQEMEVRTGSDVSIPC-VVSGVPLPEITWKKDGQMISLNGRVTILED---NT 2018 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA 1187 L I+ +D GEY+C N T+ Sbjct: 2019 LVIHKSQREDMGEYACIASNKVQTS 2043 Score = 50.4 bits (115), Expect = 5e-04 Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E + GS V C V G P P+ITW + +I S + ++ +DN TLV Sbjct: 1965 PTFLEGPQEMEVRTGSDVSIPCVVSGVPLPEITWKKDGQMI--SLNGRVTILEDN--TLV 2020 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + ED G + C+A N ++ +L++ P Sbjct: 2021 IHKSQREDMGEYACIASNKVQTSARIAKLLIIGP 2054 Score = 42.3 bits (95), Expect = 0.14 Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 6/92 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T + C V G P ++W R + + FQ + ++ TL+IR+V ED G + C Sbjct: 1889 GETAELGCIVVGLPESTVSWRRNGQPLM-GERFQSFGEN---GTLLIRDVRLEDNGMYEC 1944 Query: 584 VAKNAAGFASSTTELIV-EAPLSDHG-SEMTV 613 VA N G ++ +L V E P G EM V Sbjct: 1945 VAVNQLGEDQASVKLTVYEVPTFLEGPQEMEV 1976 Score = 41.5 bits (93), Expect = 0.25 Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 10/102 (9%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQIT---WFRQTAIIKP----SQDFQMY 559 S P F E+ + + GS F C+ +G P P++T W + + S ++Y Sbjct: 1775 SYPPTFAEEPKNRTINAGSGALFRCKADGRPTPRVTVSSWLKDGQPLSQRDLSSGRLRVY 1834 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 ++ + R ED+G +TCV +N G +S+ L+V+ Sbjct: 1835 TSSGSLQFVRTRR---EDSGNYTCVIRNTQGVNTSSAFLVVK 1873 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV C V G P +TW + + + + DD +L + +V P D G + C Sbjct: 2069 GETVVLPCTVIGAYNPVVTWQHNGEDVV-NDERHLMVDD----SLTVTDVDPADGGLYVC 2123 Query: 584 VAKNAAGFASSTTELIVEAPL 604 A N G S+ + + P+ Sbjct: 2124 TATNTEGAVSANAYVSITGPV 2144 >UniRef50_P79757 Cluster: Connectin/titin; n=3; Amniota|Rep: Connectin/titin - Gallus gallus (Chicken) Length = 1021 Score = 112 bits (269), Expect = 1e-22 Identities = 182/774 (23%), Positives = 302/774 (39%), Gaps = 109/774 (14%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +P T KP++ V EG C + P P I W+ G+ IV + Y Sbjct: 326 LPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRAGQPIVSSRRFQIT----RTQY 381 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S +I+ V+ EG+YTVV N EG L ++ K P E Sbjct: 382 KSTFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQ--RKRIP--------------EK 425 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD-EGVYTLKAENS 810 I S + +P P + K+ +PVK+ PK+VK E + T S Sbjct: 426 AITSPPRIKSPEPRV---KSPEPVKS----------------PKRVKSPEPISTPSKAKS 466 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 +T+ V V+ PT A PP + + T+ +K + + + + WY++ Sbjct: 467 PPGDKTAPVEKVQLPT---ASPPKIKEQLKAETLGDKVKLSCAVESSVLSIREVAWYKDG 523 Query: 871 EIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 + + ++ + EL I N+ +E D G+Y C G S + T V K Sbjct: 524 KKLKEDHHFKFHYAADGTYELKIHNL-TESDKGEYTCEIMGEGGISKTNFQFTGQVFKNI 582 Query: 930 FVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 H Q +E K+V + VST+ KK + + + I+E Sbjct: 583 ---HSQVQSVSETPKSV-EKGDKVLAVSTQ----KKSSAATEEKAAIEE----------- 623 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVW 1049 VIK + ++ VK+ E V E L+ I ++V W Sbjct: 624 ------VIKKSIVTED------VKQLQAEIRASSTQMTVSEGQKVTLKANIPG-ASEVKW 670 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR-DE---SCTAEVTVVEL 1105 +G ++ + Y + G L I+ S DEG +C + DE C +T + Sbjct: 671 VLNGMELR-NSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEGTIKCQYVLTFSKE 729 Query: 1106 P---PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK 1160 P P IT+ ++Q VN+G F E++ GD V W ++ I S+H++ T Sbjct: 730 PSNEPAFITQPKSQNVNEGQDVLFTCEVS-GDPSPEVEWLRNNQPIAVSSHMRATRSKNT 788 Query: 1161 QKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 L+I + + D G+Y+ + G TA LTV P I P+ +++ + DA + Sbjct: 789 YSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTV-FPLIE---EPPKEVVLKTSGDASM 844 Query: 1217 TVEIPDETLDVTWYKKKSVIED------TE-KFTLISDVKKRTL---IIRKCTEDDQCEY 1266 ++ + K+++ TE KF +S ++ + + + Sbjct: 845 HESFSSQSFQMAASKQEASFSSFSSSSMTETKFASMSAKSMSSMKESFVEMSSSSIMGKS 904 Query: 1267 TCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS- 1325 + L++ ++ LK V PPKI + I G +TL + P P W Sbjct: 905 SMAQLESSTSKMLKSGVRGVPPKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGR 964 Query: 1326 KIIKKCKHTKPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 KI + + + I++ +L I V+ D GIY L L N G +N+ I Sbjct: 965 KITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLGNEFGTDSATVNINI 1018 Score = 76.6 bits (180), Expect = 7e-12 Identities = 66/318 (20%), Positives = 129/318 (40%), Gaps = 20/318 (6%) Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 L IP + +V W + +++ + TL I+K + D+ TC + Sbjct: 658 LKANIPGAS-EVKWVLNGMELRNSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEG 716 Query: 1276 TTKLKVEVVEFP------PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 T K + V+ F P + + + G DV + P P EW+ N++ I Sbjct: 717 TIKCQY-VLTFSKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIA 775 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 H + + + SL I+ +D G Y ++ +N G ++T+ P K + Sbjct: 776 VSSHMRATRSKNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIEEPPKEVV 835 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 L+ + + +S QE + + S ++T+T+ + + K+ SS Sbjct: 836 LKTSGDA------SMHESFSSQSFQMAASKQEASFSSF-SSSSMTETKFASMSAKSMSSM 888 Query: 1450 RFRAYAVNEVDISDASETTEY----YKVIKE-TKIQSPTVEKPLKNITTEPNEDIELTCI 1504 + ++ I S + K++K + P +E +I+ + + + L+C Sbjct: 889 KESFVEMSSSSIMGKSSMAQLESSTSKMLKSGVRGVPPKIEALPSDISIDEGKVLTLSCA 948 Query: 1505 FGGVPQPKVTWYRDGKKL 1522 F G P P++TWY G+K+ Sbjct: 949 FSGEPAPEITWYCRGRKI 966 Score = 66.5 bits (155), Expect = 8e-09 Identities = 126/613 (20%), Positives = 220/613 (35%), Gaps = 48/613 (7%) Query: 1094 ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHI 1152 E T + ++ P I R+++ +V G+ F + + +K A V+W+ +G E+Q S+ I Sbjct: 128 EVLTQQPFTLDHAPRITLRMRSHRVPCGHNTRFILNVQSKPTADVKWYHNGIELQESSKI 187 Query: 1153 QLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK--CTAILTVEEPSINFTLRLPE--FILV 1208 + L+I DC +DD+G Y N K C+ T++ ++T + V Sbjct: 188 HFSNTSGVLTLEILDCHIDDSGTYRAVCTNYKGECSDYATLDVTGGDYTTYSSQRRDEEV 247 Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYT 1267 P + LT E V+ +KK + E + + S+V + E Sbjct: 248 PRSILPDLT---RTEAYAVSSFKKATAAEASSSVREVKSEVSATRESLLSYEHHASSEEK 304 Query: 1268 CVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 + KS + V P I+ R + G D P P W+ Sbjct: 305 ITASEEKSLEERTVHKAFKSTLPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRA 364 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK---- 1380 + I + + + ++ I V+ D G Y + +EN+ G + +T+ K Sbjct: 365 GQPIVSSRRFQITRTQYKSTFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQRKRIPE 424 Query: 1381 ---PSPP----GKPNIL--EIDSSSINICWDEPENTGNSTII-----YYVVEYQEIDTTE 1426 SPP +P + E S + EP +T + VE ++ T Sbjct: 425 KAITSPPRIKSPEPRVKSPEPVKSPKRVKSPEPISTPSKAKSPPGDKTAPVEKVQLPTAS 484 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD-ISDASETTEYYKVIKETKIQSPTVE 1485 +K K +T +K + + ++ EV D + E + K T E Sbjct: 485 PPKIKEQLKAETLGDKVKLSCAVESSVLSIREVAWYKDGKKLKEDHH-FKFHYAADGTYE 543 Query: 1486 KPLKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544 + N+T ++ E TC I G K + G+ K + ++ Sbjct: 544 LKIHNLT--ESDKGEYTCEIMGEGGISKTNFQFTGQVFKNIHSQVQSVSETPKSVEKGDK 601 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ-KHKVGDEWLVTAVIEG----- 1598 + E + + + +K ++T ED+KQ + ++ V EG Sbjct: 602 VLAVSTQKKSSAATEEKAAIEEVIKKSIVT---EDVKQLQAEIRASSTQMTVSEGQKVTL 658 Query: 1599 ---IP-PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 IP EV W NG +L N +Y + IK+ T E GT Sbjct: 659 KANIPGASEVKWVLNGMELRNSDDYRYGISGSNHTLTIKKASNKDEGILTCEGKTDEGTI 718 Query: 1655 SVEVTLKVYDKPS 1667 + L +PS Sbjct: 719 KCQYVLTFSKEPS 731 Score = 65.7 bits (153), Expect = 1e-08 Identities = 65/297 (21%), Positives = 117/297 (39%), Gaps = 11/297 (3%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F +PK+Q V+EG D+L C + P P++ WL + I ++ + + Sbjct: 734 PAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIAVSSHMRATRSKNTYS--- 790 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+I N G YTV A N G+ S L + +EPP+ + S ES Sbjct: 791 -LEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIEEPPKEVVLKTSGDASMHESFS 849 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 + + + ++ + + S++ +K V + ++ ++S Sbjct: 850 SQSFQMAASKQEASFSSFSSSSMTETKFASMSAKSMSSMKESFV-EMSSSSIMGKSSMAQ 908 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEI 872 E+S ++ PP +I++ E + L + P P ITWY R +I Sbjct: 909 LESSTSKMLKSGV--RGVPPKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGRKI 966 Query: 873 ISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 S + + + E++ +I + D G Y N G S A V I++ + Sbjct: 967 TSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLGNEFGTDS--ATVNINIRSI 1021 Score = 56.8 bits (131), Expect = 6e-06 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+E S P F+ + + ++ +G V F C+V G P P++ W R I S + Sbjct: 727 SKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWLRNNQPIAVSSHMRA-TRS 785 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 N +L IR D G +T AKN G S+T L V Sbjct: 786 KNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTV 823 Score = 52.8 bits (121), Expect = 1e-04 Identities = 31/129 (24%), Positives = 53/129 (41%), Gaps = 2/129 (1%) Query: 1550 CIAFNDHGEVETSCVVGIQQKPVI--TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 C D G ++ V+ ++P + Q G + L T + G P PEV W Sbjct: 709 CEGKTDEGTIKCQYVLTFSKEPSNEPAFITQPKSQNVNEGQDVLFTCEVSGDPSPEVEWL 768 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 +N + T + T + I+ S + KYT++A N G S +L V+ Sbjct: 769 RNNQPIAVSSHMRATRSKNTYSLEIRNAAVSDTGKYTVKAKNYHGQCSATASLTVFPLIE 828 Query: 1668 KPEGPVIMR 1676 +P V+++ Sbjct: 829 EPPKEVVLK 837 Score = 50.0 bits (114), Expect = 7e-04 Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 4/157 (2%) Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIP 633 F + T T A +A SS E VE S + ++ + + G+P Sbjct: 867 FSSSSMTETKFASMSAKSMSSMKESFVEMSSSSIMGKSSMAQLESSTSKMLKSGV-RGVP 925 Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMHMYC 692 P P +DEG + L C P P+I W +G +I D+ IE+ + Sbjct: 926 PKIEALPSDISIDEGKVLTLSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDL-- 983 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 + L I +V+K G YT+ N G S + + I++ Sbjct: 984 TTLIIMDVQKNDGGIYTLNLGNEFGTDSATVNINIRS 1020 Score = 46.0 bits (104), Expect = 0.011 Identities = 29/97 (29%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 + ++ + K R +G T +F C V+G P P ITW R I S+ FQ+ Sbjct: 323 KSTLPATILTKPRSITVSEGETARFSCDVDGEPAPTITWVRAGQPIVSSRRFQITRTQYK 382 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +T I V D G++T V +N+ G + L V+ Sbjct: 383 -STFEISLVQIADEGSYTVVVENSEGRQEAHFTLTVQ 418 Score = 44.0 bits (99), Expect = 0.046 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 ++ G P PE+ WY G K+ + + ++I T E + + I +++++ YT+ Sbjct: 945 LSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGIYTLNLG 1004 Query: 1649 NTAGTSSVEVTLKV 1662 N GT S V + + Sbjct: 1005 NEFGTDSATVNINI 1018 Score = 42.3 bits (95), Expect = 0.14 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Query: 523 DGSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYD-DDNVATLVIREVFPEDAGT 580 +G + C G P P+ITW+ R I Q + + + +++ TL+I +V D G Sbjct: 939 EGKVLTLSCAFSGEPAPEITWYCRGRKITSQDQQGRFHIETSEDLTTLIIMDVQKNDGGI 998 Query: 581 FTCVAKNAAGFASSTTELIVEA 602 +T N G S+T + + + Sbjct: 999 YTLNLGNEFGTDSATVNINIRS 1020 >UniRef50_Q23991 Cluster: Peroxidasin precursor; n=7; Coelomata|Rep: Peroxidasin precursor - Drosophila melanogaster (Fruit fly) Length = 1535 Score = 112 bits (269), Expect = 1e-22 Identities = 100/428 (23%), Positives = 172/428 (40%), Gaps = 31/428 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+ + G V+ C+V G RPQITW T + + Q +L+ Sbjct: 238 PQFLVAPQDAQVAAGEQVELSCEVTGLHRPQITWMHNTQELGLEEQTQAEILPS--GSLL 295 Query: 570 IREVFPEDAGTFTCVAKNAAG-FASSTTELIV-------EAPLSDHGSEMTVXXXX-XXX 620 R D G + C+A+N G S L+V ++P+ +++ Sbjct: 296 HRSADTSDMGIYQCIARNEMGALRSQPVRLVVNGGNHPLDSPIDARSNQVWADAGTPTHG 355 Query: 621 XXXXXADILEGIPPTFSKKPKAQYV--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 + PP F+ +P Q V +LL+C P+PDI W G +++ Sbjct: 356 ATPLPSPSPSHSPPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLL-QS 414 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 S+ ++++ L + + GTY A N G +++ KE P+++ Sbjct: 415 TPSLQLQAN-----GSLILLQPNQLSAGTYRCEARNSLGSVQATARIEL----KELPEIL 465 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHSITILKPKKV 797 +S ++ G++ +L GNP PTI W N P+ P + ++ ++ + Sbjct: 466 TAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTELVVGAARQ 525 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVT 857 + GVY A N G ETS T++ E + PP + TI+L + Sbjct: 526 EHAGVYRCTAHNENG--ETSVEATIK--VERSQSPPQLAIEPSNLVAITGTTIELPCQAD 581 Query: 858 R-NPVPSITWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKS 915 + I+W + +I P+ + + + L + NV D G Y+C N G++ Sbjct: 582 QPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIP-DGGRYECQLKNQFGRA 640 Query: 916 SHGARVTI 923 S A VTI Sbjct: 641 SASALVTI 648 Score = 66.9 bits (156), Expect = 6e-09 Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 5/172 (2%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 L C G PQP + W+ +G++L T + Y+C A N G Sbjct: 390 LDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLILLQPNQLSAGTYRCEARNSLGS 449 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 V+ + + +++ P I + + Q K+G +++ +G P P + W NG L + Sbjct: 450 VQATARIELKELPEILTAPQS--QTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTP 507 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 E T ++ + ++ H+ Y A N G +SVE T+KV S P+ Sbjct: 508 DLQLENENTELV-VGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQ 558 Score = 56.8 bits (131), Expect = 6e-06 Identities = 63/295 (21%), Positives = 119/295 (40%), Gaps = 25/295 (8%) Query: 832 PPLFINR--FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 PP F ++ Q + + G + L + P P I W+ N + S Q ++ Sbjct: 368 PPHFTHQPHDQIVALHSSGHVLLDCAASGWPQPDIQWFVNGRQLLQSTPSLQLQANGSLI 427 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 L+ N ++ +G Y+C A NS G AR I+++++ + +S + GK +LE Sbjct: 428 LLQPN---QLSAGTYRCEARNSLGSVQATAR--IELKELPEILTAPQSQTIKLGKAFVLE 482 Query: 950 CQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--E 1005 C + W N + G + ++ E GV +C ++ E Sbjct: 483 CDADGNPLPTIDWQLNGVPLPG-NTPDLQLENENTELVVGAARQEHAGVYRCTAHNENGE 541 Query: 1006 TSTMLVVK----ETIPEFIRKLQDFEVKEKDVAILEVEINS--ETADVVWERDGEIIKPK 1059 TS +K ++ P+ + + L + + + + W DG +I P Sbjct: 542 TSVEATIKVERSQSPPQLAIEPSNLVAITGTTIELPCQADQPEDGLQISWRHDGRLIDPN 601 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTV---VELPP 1107 + + L+++N ++ D G Y C L+++ S +A VT+ V+L P Sbjct: 602 VQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKNQFGRASASALVTIRNNVDLAP 656 Score = 41.9 bits (94), Expect = 0.19 Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 14/190 (7%) Query: 1226 DVTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVE 1282 D+ W+ + +++ T L ++ +LI+ + + Y C ++ + + ++E Sbjct: 401 DIQWFVNGRQLLQSTPSLQLQAN---GSLILLQPNQLSAGTYRCEARNSLGSVQATARIE 457 Query: 1283 VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 + E P +I+ + IK G L D P P +W +N + +++++ Sbjct: 458 LKELP-EILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPG-NTPDLQLENEN 515 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG---KP-NILEIDSSSIN 1398 L + AG+Y+ N G VE + + SPP +P N++ I ++I Sbjct: 516 TELVVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIE 575 Query: 1399 I-CW-DEPEN 1406 + C D+PE+ Sbjct: 576 LPCQADQPED 585 Score = 37.1 bits (82), Expect = 5.3 Identities = 56/253 (22%), Positives = 94/253 (37%), Gaps = 18/253 (7%) Query: 1137 VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--KCTAILTVEE 1193 ++WF +G ++ Q + +QL +G L + + AG Y CE NS A +E Sbjct: 402 IQWFVNGRQLLQSTPSLQLQANGS---LILLQPNQLSAGTYRCEARNSLGSVQATARIEL 458 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 + L P+ + L + L ++ V L + + L Sbjct: 459 KELPEILTAPQSQTIKLGKAFVLECDADGNPLPTIDWQLNGVPLPGNTPDLQLENENTEL 518 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 ++ ++ Y C + T +KVE + PP++ G+ + L Sbjct: 519 VVGAARQEHAGVYRCTAHNENGETSVEATIKVERSQSPPQLAIEPSNLVAITGTTIEL-- 576 Query: 1310 DYQAFPQPND----EWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLEN 1364 QA QP D W + ++I S + SL +K V D G Y+ +L+N Sbjct: 577 PCQA-DQPEDGLQISWRHDGRLIDPNVQLAEKYQISGAGSLFVKNVTIPDGGRYECQLKN 635 Query: 1365 NCGHADVEMNVTI 1377 G A VTI Sbjct: 636 QFGRASASALVTI 648 >UniRef50_UPI0000E80BF7 Cluster: PREDICTED: similar to bone specific CMF608; n=2; Gallus gallus|Rep: PREDICTED: similar to bone specific CMF608 - Gallus gallus Length = 1817 Score = 111 bits (267), Expect = 2e-22 Identities = 203/942 (21%), Positives = 355/942 (37%), Gaps = 89/942 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P K A V SD + C P+P I W ++ PD + + + Sbjct: 845 PRIIGGKLAAFTVLANSDAFIPCEATGNPQPTIEWT----KMSPDTDAPASGSRWTVLPN 900 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I G Y A N G A L L + PP++ + + G V Sbjct: 901 GTLAIAQAALQDGGQYRCTATNVLGTARLLATLAVVA---YPPRIAGSTRLLTAHAGMPV 957 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT------ILKPKKVKDEGVYTLK 806 + G P P+I+W N + + S G+ + +K V D G+YT Sbjct: 958 AMRCPAEGRPPPSISWVLANGT--HVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCT 1015 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVPSIT 865 A N G T A +TV+ + A PP+ + + Q+I + L NP P + Sbjct: 1016 ATNPAG---TDA-LTVK--LQVIAAPPIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVH 1069 Query: 866 WYRNN-EIISPSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + + P + + T+ N L ++++ DSG+Y+C+A++S G +T+ Sbjct: 1070 WVLSKGTAVKPLQFVNTRVLLLPNGTLQLSSI-VPADSGNYECIATSSTGSERRVVILTV 1128 Query: 924 DVEKV--TFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHR--EIIQ 977 Q + G ++L C + + W K + HR I Sbjct: 1129 RHRDTLPRIAAASQGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIH 1188 Query: 978 EGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFE---VKEK 1031 D G C+ +++ ++++K +I P I + Q F+ K Sbjct: 1189 VYPNGSLVIEAVTEKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFKKLVPYGK 1248 Query: 1032 DVAILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRGH------IRKLYIRNTSVHDE 1084 D + S ++ W DG +I D R LY+ V +E Sbjct: 1249 DFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAGVTEE 1308 Query: 1085 GEYSCILRD----ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELT-KGDALVR 1138 G+Y+C ++ + VTVV P+I + KV G+ A + E + + Sbjct: 1309 GDYTCYAQNSLGRDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIF 1368 Query: 1139 WFKDGSEIQFSN---HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-----SKCTAI-L 1189 W S+I S+ H+ L ++G L + L DAGEY C N +K + + Sbjct: 1369 WLLPSSDIISSSTDRHL-LHVNG---SLSVRRAKLLDAGEYMCVARNAGGDDTKLYKLDV 1424 Query: 1190 TVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKF-TLI 1245 + P IN I V A + ++ E + W ++ + + I Sbjct: 1425 DAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRI 1484 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEF---PPKIVDYEREYRIK 1300 K TL IR D ++ CV + +S +++EV+E P + + K Sbjct: 1485 VIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAK 1544 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 G +TL P P W++ N + K T + + +L+I+ AG Y+ Sbjct: 1545 PGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYR 1604 Query: 1360 LRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSINICWDEPENTGNSTII-- 1413 +N G+ + + + + KP+ P G + +S S++ D + + Sbjct: 1605 CAAKNQVGYIEKLIVLEVAQKPTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPG 1664 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 +V++ +I++ I ++N T + +Y RA+ D S T V Sbjct: 1665 GHVLDRPQINSRH-ILLENGTLV-IRAATIHDRGNYVCRAHN----PAGDFSITIPVTIV 1718 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 +I +P + I T P ++L+C G+P+P++TW Sbjct: 1719 AYPPRI----TNRPPQTIHTMPGAAVQLSCTALGIPRPEITW 1756 Score = 74.1 bits (174), Expect = 4e-11 Identities = 98/438 (22%), Positives = 175/438 (39%), Gaps = 32/438 (7%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLL 1308 TL + + ++ +YTC ++ + K+ V VV P+I Y+ ++K G L Sbjct: 1297 TLYLNRAGVTEEGDYTCYAQNSLGRDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLD 1356 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 + P+P W++ S I T + + SL++++ + DAG Y + + N G Sbjct: 1357 CEAAGEPKPKIFWLLPSSDIISSS-TDRHLLHVNGSLSVRRAKLLDAGEY-MCVARNAGG 1414 Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE---------PENTGNSTIIYYVVEY 1419 D ++ LD + P N L + + I + E T I++ + + Sbjct: 1415 DDTKLYK--LDVDAKPPIINGLYTNKTIIKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDN 1472 Query: 1420 QEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + + S I K T I+NL+ + + F A N+ S E ++++ Sbjct: 1473 IFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICVARNDWGESVLVVRLEVLEMLRRPM 1532 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYE----NRX 1533 ++P EK I +P + I L C G P P+V+W +G L T E + Sbjct: 1533 FKNPFNEK----IIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNG 1588 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y+C A N G +E V+ + QKP I +++ + G+ + Sbjct: 1589 TLSIRNPSRDKAGKYRCAAKNQVGYIEKLIVLEVAQKPTI-LTHPKGPMRGISGESLSLH 1647 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYN---ITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + +G P P W G + + + N I + T VIR + Y A N Sbjct: 1648 CLSDGSPKPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATI--HDRGNYVCRAHNP 1705 Query: 1651 AGTSSVEVTLKVYDKPSK 1668 AG S+ + + + P + Sbjct: 1706 AGDFSITIPVTIVAYPPR 1723 Score = 69.7 bits (163), Expect = 8e-10 Identities = 99/430 (23%), Positives = 164/430 (38%), Gaps = 51/430 (11%) Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVAT 567 PI +E+ R + G + C EG P+P + W + +KP Q T Sbjct: 1036 PIILEEKRQQIAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPLQFVNTRVLLLPNGT 1095 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXAD 627 L + + P D+G + C+A ++ G S +++ +TV D Sbjct: 1096 LQLSSIVPADSGNYECIATSSTG---SERRVVI----------LTV----------RHRD 1132 Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 L I + + D+ +LL C P+P I W + +V + + S Sbjct: 1133 TLPRIAAASQGMTQLSFGDK---LLLNCTATGEPQPRIMWRLPSKAVVDQWH---RMGSR 1186 Query: 688 MHMYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 +H+Y + L I V + G Y VA N+ G+ I++K+ K + +V Sbjct: 1187 IHVYPNGSLVIEAVTEKDAGDYLCVARNKIGDDL--ILMKVSITMKPAKIDQKQYFKKLV 1244 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH----------SITILKPKK 796 G+ + + G+P P I+W + V +D H L Sbjct: 1245 PYGKDFQVDCKASGSPAPEISWSLPDGMVINNAMLADDSGHRARRYVLFDNGTLYLNRAG 1304 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 V +EG YT A+NS G E +TV A P + + + VK T L Sbjct: 1305 VTEEGDYTCYAQNSLGRDEMKIHVTV-----VTAAPQIKHSYKTYVKVKAGDTALLDCEA 1359 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P I W + I S T ++ N L + +D+G+Y CVA N+ G + Sbjct: 1360 AGEPKPKIFWLLPSSDIISSST-DRHLLHVNGSLSVRRA-KLLDAGEYMCVARNAGGDDT 1417 Query: 917 HGARVTIDVE 926 ++ +D + Sbjct: 1418 KLYKLDVDAK 1427 Score = 66.9 bits (156), Expect = 6e-09 Identities = 93/399 (23%), Positives = 142/399 (35%), Gaps = 51/399 (12%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S Q +C+ EG P PQI W I + + TL IR + P D F CV Sbjct: 1449 SKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPSDTADFICV 1508 Query: 585 AKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 A+ +D G + V ++LE + K P + Sbjct: 1509 AR------------------NDWGESVLVVRL----------EVLEMLRRPMFKNPFNEK 1540 Query: 645 V--DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 + G I L C + P P+++W+ + + + L I N + Sbjct: 1541 IIAKPGKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSN---GTLSIRNPSR 1597 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 + G Y A N+ G IVL++ ++P + P M GES+ L G+P Sbjct: 1598 DKAGKYRCAAKNQVGYIEKLIVLEVA---QKPTILTHPKGPMRGISGESLSLHCLSDGSP 1654 Query: 763 RPTITWCKNNKPVKALPTKSDGDT---HSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 +P+ W V P + + +++ + D G Y +A N G + Sbjct: 1655 KPSTAWTLPGGHVLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIP 1714 Query: 820 ITVEEPTEENAEPPLFINRF-QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 +T+ A PP NR Q I ++L P P ITW + I + Sbjct: 1715 VTIV------AYPPRITNRPPQTIHTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGN 1768 Query: 879 ITQNFDGENIE----LVITNVDSEIDSGDYKCVASNSAG 913 + E + L I N DSG YKC A N G Sbjct: 1769 HGRASGSELLHPQGTLRIQNPQPS-DSGTYKCTARNHLG 1806 Score = 54.0 bits (124), Expect = 4e-05 Identities = 129/649 (19%), Positives = 227/649 (34%), Gaps = 39/649 (6%) Query: 1074 LYIRNTSVHDEGEYSC----ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIE 1129 L I ++ D G+Y C +L A + VV PP I + + G Sbjct: 903 LAIAQAALQDGGQYRCTATNVLGTARLLATLAVVAYPPRIAGSTRLLTAHAGMPVAMRCP 962 Query: 1130 LT-KGDALVRW-FKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCT 1186 + + W +G+ + S+ Q + L I D + D G Y+C N T Sbjct: 963 AEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGT 1022 Query: 1187 AILTVE-----EPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTE 1240 LTV+ P I + + I A D L V W K Sbjct: 1023 DALTVKLQVIAAPPIILEEKRQQ-IAATAGQDLNLPCTAEGNPQPHVHWVLSKGTAVKPL 1081 Query: 1241 KF--TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK----LKVEVVEFPPKIVDYE 1294 +F T + + TL + D Y C+ + + + L V + P+I Sbjct: 1082 QFVNTRVLLLPNGTLQLSSIVPADSGNYECIATSSTGSERRVVILTVRHRDTLPRIAAAS 1141 Query: 1295 REY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS--KSASLTIKKVE 1351 + ++ G + L PQP W + SK + H S + SL I+ V Sbjct: 1142 QGMTQLSFGDKLLLNCTATGEPQPRIMWRLPSKAVVDQWHRMGSRIHVYPNGSLVIEAVT 1201 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNS 1410 DAG Y N G + M V+I KP+ K ++ + D + + Sbjct: 1202 EKDAGDYLCVARNKIGDDLILMKVSITMKPAKIDQKQYFKKLVPYGKDFQVDCKASGSPA 1261 Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETT-- 1468 I + + + ++ + + + + + Y RA E D + ++ + Sbjct: 1262 PEISWSLPDGMVINNAMLADDSGHRARRYVL-FDNGTLYLNRAGVTEEGDYTCYAQNSLG 1320 Query: 1469 -EYYKVIKETKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---K 1523 + K+ +P ++ K + + + L C G P+PK+ W + Sbjct: 1321 RDEMKIHVTVVTAAPQIKHSYKTYVKVKAGDTALLDCEAAGEPKPKIFWLLPSSDIISSS 1380 Query: 1524 TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT---ISNEDI 1580 T + Y C+A N G+ + + KP I +N+ I Sbjct: 1381 TDRHLLHVNGSLSVRRAKLLDAGEYMCVARNAGGDDTKLYKLDVDAKPPIINGLYTNKTI 1440 Query: 1581 KQKHKVG-DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEY-NITTKEKTSVIRIKELKRS 1638 + V + + EG PPP+++W N Y + K + I+ L+ S Sbjct: 1441 IKVTAVRHSKKQIDCRAEGTPPPQIMWIMPDNIFLTAPYYGSRIVIHKNGTLEIRNLRPS 1500 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKP--EGPVIMREISRESVTI 1685 ++ + A N G S + V L+V + +P + P + I++ TI Sbjct: 1501 DTADFICVARNDWGESVLVVRLEVLEMLRRPMFKNPFNEKIIAKPGKTI 1549 Score = 46.8 bits (106), Expect = 0.007 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 9/128 (7%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 +E +YT Y Q L D++ + + + + ++ K G T +C+ G Sbjct: 1307 EEGDYTCYAQNSLGR--DEMKIHVTVVTAAPQIKHSYKTYVKVKA---GDTALLDCEAAG 1361 Query: 536 YPRPQITWFRQTA-IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 P+P+I W ++ II S D + + + +L +R DAG + CVA+NA G + Sbjct: 1362 EPKPKIFWLLPSSDIISSSTDRHLLHVN---GSLSVRRAKLLDAGEYMCVARNAGGDDTK 1418 Query: 595 TTELIVEA 602 +L V+A Sbjct: 1419 LYKLDVDA 1426 Score = 46.0 bits (104), Expect = 0.011 Identities = 44/196 (22%), Positives = 69/196 (35%), Gaps = 12/196 (6%) Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT----AKATYENRXXXXXXXXXXX 1543 L T N D + C G PQP + W + ++ T Sbjct: 852 LAAFTVLANSDAFIPCEATGNPQPTIEWTKMSPDTDAPASGSRWTVLPNGTLAIAQAALQ 911 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 Y+C A N G + + P + + H G + EG PPP Sbjct: 912 DGGQYRCTATNVLGTARLLATLAVVAYPPRIAGSTRLLTAH-AGMPVAMRCPAEGRPPPS 970 Query: 1604 VIWY-KNGNKLENDKEYNITTKEKTS-VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 + W NG + + + N + + IK++ YT A+N AGT ++ V L+ Sbjct: 971 ISWVLANGTHVSSSSQGNQKVLVRPDGTLTIKDVTVYDRGLYTCTATNPAGTDALTVKLQ 1030 Query: 1662 VYDKPSKPEGPVIMRE 1677 V P P+I+ E Sbjct: 1031 VIAAP-----PIILEE 1041 Score = 45.6 bits (103), Expect = 0.015 Identities = 51/199 (25%), Positives = 74/199 (37%), Gaps = 18/199 (9%) Query: 634 PTFSKKPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PT PK G + L C P+P AW G ++ I+ + + Sbjct: 1626 PTILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGHVLDRPQIN---SRHILLEN 1682 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE-PLKSMIVRQGES 751 L I G Y A N G+ S+ I + I PP++ P +++ G + Sbjct: 1683 GTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVA---YPPRITNRPPQTIHTMPGAA 1739 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK--------KVKDEGVY 803 V LS +G PRP ITW + + L T + G +L P+ + D G Y Sbjct: 1740 VQLSCTALGIPRPEITWELPDHSI--LSTGNHGRASGSELLHPQGTLRIQNPQPSDSGTY 1797 Query: 804 TLKAENSEGIAETSAVITV 822 A N G T I V Sbjct: 1798 KCTARNHLGSDFTVTYIHV 1816 Score = 44.8 bits (101), Expect = 0.026 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 520 HTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPE 576 HT G+ VQ C G PRP+ITW +I+ + + TL I+ P Sbjct: 1733 HTMPGAAVQLSCTALGIPRPEITWELPDHSILSTGNHGRASGSELLHPQGTLRIQNPQPS 1792 Query: 577 DAGTFTCVAKNAAGFASSTTELIV 600 D+GT+ C A+N G + T + V Sbjct: 1793 DSGTYKCTARNHLGSDFTVTYIHV 1816 Score = 44.4 bits (100), Expect = 0.035 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 524 GSTVQFECQVEGYPRPQITWF--RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 G V C EG P P I+W T + SQ Q + TL I++V D G + Sbjct: 954 GMPVAMRCPAEGRPPPSISWVLANGTHVSSSSQGNQKVLVRPD-GTLTIKDVTVYDRGLY 1012 Query: 582 TCVAKNAAGFASSTTEL-IVEAP 603 TC A N AG + T +L ++ AP Sbjct: 1013 TCTATNPAGTDALTVKLQVIAAP 1035 Score = 40.7 bits (91), Expect = 0.43 Identities = 19/68 (27%), Positives = 30/68 (44%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T+ C V+G P P+++W + + + TL IR + AG + C Sbjct: 1546 GKTITLNCSVDGNPPPEVSWMLPNGMWLSKGTGTPEFLPGSNGTLSIRNPSRDKAGKYRC 1605 Query: 584 VAKNAAGF 591 AKN G+ Sbjct: 1606 AAKNQVGY 1613 Score = 37.9 bits (84), Expect = 3.0 Identities = 44/186 (23%), Positives = 75/186 (40%), Gaps = 12/186 (6%) Query: 749 GESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSDGDTHSIT----ILKPKKVKDEGVY 803 G +V L Q +G P P I W + V+A DG + L+ D G+Y Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTFDTGLY 583 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 N + ITV +P E++ +N Q ++ + L T P + Sbjct: 584 HCIGTNYNDADILTFRITVVDPYVEHSS----VNGAQ-LSAAVGSILDLPCTSTAVPDAA 638 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++W ++ ++ +N L I V +E DSG ++CVA++ G +V + Sbjct: 639 VSWVLPERVVL-HHSVRNRHIFDNGTLRIQGV-TERDSGYFRCVAASQYGVDLLVFQVLV 696 Query: 924 DVEKVT 929 +K T Sbjct: 697 RKDKST 702 Score = 37.5 bits (83), Expect = 4.0 Identities = 30/113 (26%), Positives = 41/113 (36%), Gaps = 8/113 (7%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 EK+ L V +KPT I P G ++ C +G P+P W Sbjct: 1615 EKLIVLEVAQKPT--------ILTHPKGPMRGISGESLSLHCLSDGSPKPSTAWTLPGGH 1666 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + + TLVIR D G + C A N AG S T + + A Sbjct: 1667 VLDRPQINSRHILLENGTLVIRAATIHDRGNYVCRAHNPAGDFSITIPVTIVA 1719 Score = 36.3 bits (80), Expect = 9.2 Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 6/90 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQ--TAIIKP--SQDFQMYYDDDNVATLVIREVFPEDAG 579 G TVQ +CQ G P P I W + + P S+D ++ TL + F D G Sbjct: 524 GGTVQLDCQAIGEPAPAIEWILADGSKVRAPYVSEDGRIIVVKSGTFTLRTADTF--DTG 581 Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGS 609 + C+ N T + V P +H S Sbjct: 582 LYHCIGTNYNDADILTFRITVVDPYVEHSS 611 >UniRef50_UPI0000D56997 Cluster: PREDICTED: similar to CG8581-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG8581-PA, isoform A - Tribolium castaneum Length = 1429 Score = 111 bits (267), Expect = 2e-22 Identities = 144/641 (22%), Positives = 257/641 (40%), Gaps = 52/641 (8%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I N+K + ++ A N D DAS T + ++ +KP I N+DI Sbjct: 265 ITNIKEEDAGTYQCRAANREDSLDASATIQ-------VQVPPRFRKKPQDKIENA-NKDI 316 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 EL C G P+PK++W++DG+ + + Y+ N ++C A N G Sbjct: 317 ELECSVYGNPEPKISWFKDGEAI-ISNDYYQIVNGHNLKIMGLMPSDSGIFQCFASNPAG 375 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 ++ + + + P + K + D+ + + P + + + Sbjct: 376 NIQAAASLKVLN-PGPKKRKKSKKNRDNPIDQMQSFTLFSHLKPDSSARLGDVDFGHFAR 434 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEA----------------SNTAGTSSVEVTLK 1661 N +S I + +R+ SS + E+ S+T+ T+ V Sbjct: 435 RKNFMQDSSSSSQTIYDPQRAFSSLKSSESYDNINLGDTQHAFFPPSSTSITAESSVAKT 494 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 P P+ + + VT+ W+ PL + + Y + + + RW +V + R Sbjct: 495 TEGFPGPPQD-LKAPIVKARFVTLSWRAPLVNSD-NIHTYTVYYRQEGSERW-RVQNTSR 551 Query: 1722 D-VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 +E I L + Y FRV+A N VG + ES + ++ V S Sbjct: 552 SRLEEINIAGLTPSKVYHFRVVAINSVGAGVSSESLTVTTQSEEHVASAPTHFVAYAT-S 610 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 ++Y+ W P E G+ I+ Y V + + + LS+ T Y + Sbjct: 611 PRTIYLNWRPPETPNGN-ILRYMVYYMETSSSVEHNIDTTELKYHLVGLSVYTEYSVWVV 669 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESN-GGSPIT 1898 A NE G +D+KI +TL+ PS+P + + E TS +V ++W P IT Sbjct: 670 AVNENGPGA--ATDEKIV--RTLSASPSEPPSNITLEPTSTTVIVRWEPPPPEYQNGVIT 725 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 Y ++++ K T VT + + + +++ E ++ A N G S PTE +V Sbjct: 726 GYKLKYRKQGKKGVT--VTTSANERFYVLNDLERGAEYQVKLWAINVNGTSPPTEWITVE 783 Query: 1959 LEKH----ATVPSPPTAPLEIRMV--GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 K+ + VP P PL + +V SN + W TP + + Y + M Sbjct: 784 TYKNDLDESRVPDLP-GPLRVILVRPTSNKLYVLW-TPPSNQNIRVRNYILGWGKGIPDM 841 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 + + ++D T + I L N Y++ + A N++G P+ Sbjct: 842 YTQ--ELDEKTRSYLIDKLEANSEYVLSLRAANQMGPGPPV 880 Score = 95.5 bits (227), Expect = 1e-17 Identities = 149/685 (21%), Positives = 257/685 (37%), Gaps = 46/685 (6%) Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFG 1506 +YR A +N +S+ + T +E PT + +P + E +++ L C Sbjct: 172 AYRCNATGLNLYKLSNKATLTVSGDR-EEAHFVPPTFIARPKSAVVVE-GQNVSLDCAAN 229 Query: 1507 GVPQPKVTWYRDGKK-----LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 G P P +TW +DG L + + + Y+C A N ++ Sbjct: 230 GYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDA 289 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 S + +Q P +D K ++ D L +V G P P++ W+K+G + ++ Y I Sbjct: 290 SATIQVQVPPRFRKKPQD-KIENANKDIELECSVY-GNPEPKISWFKDGEAIISNDYYQI 347 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD------KPSKPEGPVIM 1675 ++I L S S + ASN AG +LKV + K SK + Sbjct: 348 VNGHN---LKIMGLMPSDSGIFQCFASNPAGNIQAAASLKVLNPGPKKRKKSKKNRDNPI 404 Query: 1676 REISRESVTIEWKPPLDD--GGLELTKYAIEKH--EPDNNRWIKVADVDRDVETYCIQKL 1731 ++ ++ KP G ++ +A K+ + ++ + D R + + Sbjct: 405 DQMQSFTLFSHLKPDSSARLGDVDFGHFARRKNFMQDSSSSSQTIYDPQRAFSSLKSSES 464 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 +N A P S ++ +E V KT P + V ++W Sbjct: 465 YDNINLGDTQHAFFPPS-STSITAESSVAKTTEGFPG-PPQDLKAPIVKARFVTLSWRAP 522 Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXARIQ--KLSINTTYQFRIYARNEIGTS 1848 N + I Y V +QEG ++W+ I L+ + Y FR+ A N +G Sbjct: 523 LVNSDN-IHTYTVYYRQEGSERWRVQNTSRSRLEEINIAGLTPSKVYHFRVVAINSVGAG 581 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 + + +T S P +FV ++ R++ L W PE+ G+ I Y++ + Sbjct: 582 VS-SESLTVTTQSEEHVASAPTHFVAYATSPRTIYLNWRPPETPNGN-ILRYMVYYMETS 639 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 I T H + + E + A N G T+ + VR + PS Sbjct: 640 SSVEHNIDTTELKYH---LVGLSVYTEYSVWVVAVNENGPGAATDEKIVR--TLSASPSE 694 Query: 1969 PTAPLEIRMVGSNIVMTSW--GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKF 2026 P + + + S V+ W PE+ G + GY + R K + V N + Sbjct: 695 PPSNITLEPT-STTVIVRWEPPPPEYQNGV-ITGYKLKYRKQGK-KGVTV-TTSANERFY 750 Query: 2027 NIRDLSENHTYMIRIYARNEIGLSEPLE--SDEPFKVIPGEGSHADEEPGEQTEVXXXXX 2084 + DL Y ++++A N G S P E + E +K E S + PG V Sbjct: 751 VLNDLERGAEYQVKLWAINVNGTSPPTEWITVETYKNDLDE-SRVPDLPG-PLRVILVRP 808 Query: 2085 XXXXXXXXWLREHNMDADIRSYARG 2109 W N + +R+Y G Sbjct: 809 TSNKLYVLWTPPSNQNIRVRNYILG 833 Score = 91.1 bits (216), Expect = 3e-16 Identities = 82/297 (27%), Positives = 128/297 (43%), Gaps = 27/297 (9%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F ++P+ V EG C +VA P I WL K E + + + + + + L Sbjct: 107 FLEEPRDLRVYEGQRAHFACHVVAAPPAKIRWL-KDERPLQIDELRMTL-----LPSGAL 160 Query: 696 KITNVKKFQEGTYTVVAV-----NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 +I V + +G Y A +A+L + + PP I KS +V +G+ Sbjct: 161 EIDEVAESDQGAYRCNATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQ 220 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPKKVKDEGVYTLK 806 +V L G P P+ITW K+ + S G T S+ I K+ +D G Y + Sbjct: 221 NVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLRITNIKE-EDAGTYQCR 279 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N E + SA I V+ PP F + Q+ I+L V NP P I+W Sbjct: 280 AANREDSLDASATIQVQ-------VPPRFRKKPQDKIENANKDIELECSVYGNPEPKISW 332 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 +++ E I S Q +G N++++ DSG ++C ASN AG A + + Sbjct: 333 FKDGEAII-SNDYYQIVNGHNLKIMGL---MPSDSGIFQCFASNPAGNIQAAASLKV 385 Score = 88.6 bits (210), Expect = 2e-15 Identities = 81/314 (25%), Positives = 128/314 (40%), Gaps = 32/314 (10%) Query: 512 FVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 F+E+ R +G F C V P +I W + +P Q ++ L I Sbjct: 107 FLEEPRDLRVYEGQRAHFACHVVAAPPAKIRWLKDE---RPLQIDELRMTLLPSGALEID 163 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEG 631 EV D G + C NA G + +L +A L+ G Sbjct: 164 EVAESDQGAYRC---NATGL--NLYKLSNKATLTVSGDREEAHF---------------- 202 Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PPTF +PK+ V EG ++ L+C P P I WL G I D + S + Sbjct: 203 VPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTI--DMTFLDSRFSKVGS- 259 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 S L+ITN+K+ GTY A NRE ++++ PP+ + + I + Sbjct: 260 TSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQV----PPRFRKKPQDKIENANKD 315 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L V GNP P I+W K+ + + + + H++ I+ D G++ A N Sbjct: 316 IELECSVYGNPEPKISWFKDGEAIISNDYYQIVNGHNLKIM-GLMPSDSGIFQCFASNPA 374 Query: 812 GIAETSAVITVEEP 825 G + +A + V P Sbjct: 375 GNIQAAASLKVLNP 388 Score = 67.3 bits (157), Expect = 4e-09 Identities = 62/245 (25%), Positives = 96/245 (39%), Gaps = 10/245 (4%) Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797 +E + + V +G+ + VV P I W K+ +P++ + + Sbjct: 108 LEEPRDLRVYEGQRAHFACHVVAAPPAKIRWLKDERPLQIDELRMTLLPSGALEIDEVAE 167 Query: 798 KDEGVYTLKAENSEGIA-ETSAVITVEEPTEE-NAEPPLFINRFQEITVKEKGTIKLVAR 855 D+G Y A A +TV EE + PP FI R + V E + L Sbjct: 168 SDQGAYRCNATGLNLYKLSNKATLTVSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCA 227 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFD--GENIELVITNVDSEIDSGDYKCVASNSAG 913 P PSITW ++ I + + F G L ITN+ E D+G Y+C A+N Sbjct: 228 ANGYPHPSITWLKDGSTIDMT-FLDSRFSKVGSTSSLRITNIKEE-DAGTYQCRAANRED 285 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMD 971 A + + V F K Q E K + LEC K W+ + + I D Sbjct: 286 SLDASATIQVQVPP-RFRKKPQDKIE-NANKDIELECSVYGNPEPKISWFKDGEAIISND 343 Query: 972 HREII 976 + +I+ Sbjct: 344 YYQIV 348 Score = 57.2 bits (132), Expect = 5e-06 Identities = 54/189 (28%), Positives = 80/189 (42%), Gaps = 16/189 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSET-ADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P FI + + V E L+ N + W +DG I F K G L Sbjct: 205 PTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVGSTSSLR 264 Query: 1076 IRNTSVHDEGEYSC--ILRDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELT- 1131 I N D G Y C R++S A T+ V++PP + Q+ K+ NK E+E + Sbjct: 265 ITNIKEEDAGTYQCRAANREDSLDASATIQVQVPPRFRKKPQD-KIENANK-DIELECSV 322 Query: 1132 --KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185 + + WFKDG I +++ Q+ ++G LKI D+G + C GN + Sbjct: 323 YGNPEPKISWFKDGEAIISNDYYQI-VNG--HNLKIMGLMPSDSGIFQCFASNPAGNIQA 379 Query: 1186 TAILTVEEP 1194 A L V P Sbjct: 380 AASLKVLNP 388 Score = 53.2 bits (122), Expect = 8e-05 Identities = 26/100 (26%), Positives = 45/100 (45%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 E + P F+ + + +G V +C GYP P ITW + + I + + Sbjct: 199 EAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDSRFSKVG 258 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + ++L I + EDAGT+ C A N ++ + V+ P Sbjct: 259 STSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQVP 298 Score = 52.4 bits (120), Expect = 1e-04 Identities = 35/95 (36%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATL 568 P F +K + K ++ EC V G P P+I+WF+ AII S D YY N L Sbjct: 299 PRFRKKPQDKIENANKDIELECSVYGNPEPKISWFKDGEAII--SND---YYQIVNGHNL 353 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + P D+G F C A N AG + L V P Sbjct: 354 KIMGLMPSDSGIFQCFASNPAGNIQAAASLKVLNP 388 Score = 37.1 bits (82), Expect = 5.3 Identities = 37/142 (26%), Positives = 66/142 (46%), Gaps = 9/142 (6%) Query: 1363 ENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWD-EPENTGNSTIIYYVVEYQ 1420 EN G A E V T+ PS P LE S+++ + W+ P N I Y ++Y+ Sbjct: 673 ENGPGAATDEKIVRTLSASPSEPPSNITLEPTSTTVIVRWEPPPPEYQNGVITGYKLKYR 732 Query: 1421 EIDTTEWISVKNITKTQTSIQN-LKTNSSYRFRAYAVNEVDISDASE--TTEYYK-VIKE 1476 + + ++V + + N L+ + Y+ + +A+N S +E T E YK + E Sbjct: 733 K-QGKKGVTVTTSANERFYVLNDLERGAEYQVKLWAINVNGTSPPTEWITVETYKNDLDE 791 Query: 1477 TKIQSPTVEKPLKNITTEPNED 1498 +++ P + PL+ I P + Sbjct: 792 SRV--PDLPGPLRVILVRPTSN 811 Score = 37.1 bits (82), Expect = 5.3 Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 13/126 (10%) Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPSPPGKPNILE----- 1391 +D K+ S I K+E + LR N G V V D+P P P ++ Sbjct: 846 LDEKTRSYLIDKLEANSEYVLSLRAANQMGPGPPVYTTVRTQDEPPPEPSPPLIPPVGLK 905 Query: 1392 ---IDSSSINICWDEPENTGNSTI---IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 + ++S+ + W + + + + YYVV+Y T +V N++ I +LK Sbjct: 906 AQILSATSVVLYWTDTTLSKSQFVRDNRYYVVKYTAERTMRTRTV-NVSDLNVMIDDLKP 964 Query: 1446 NSSYRF 1451 N+ Y F Sbjct: 965 NTLYEF 970 Score = 36.7 bits (81), Expect = 7.0 Identities = 39/173 (22%), Positives = 67/173 (38%), Gaps = 15/173 (8%) Query: 1227 VTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTC-------VLLDAKSTTK 1278 + W K + ++ D + TL+ L I + E DQ Y C L K+T Sbjct: 136 IRWLKDERPLQIDELRMTLLPS---GALEIDEVAESDQGAYRCNATGLNLYKLSNKATLT 192 Query: 1279 LKVEVVE---FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC-KHT 1334 + + E PP + + + G +V+L +P P+ W+ + I + Sbjct: 193 VSGDREEAHFVPPTFIARPKSAVVVEGQNVSLDCAANGYPHPSITWLKDGSTIDMTFLDS 252 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 + S ++SL I ++ DAG Y+ R N D + + P KP Sbjct: 253 RFSKVGSTSSLRITNIKEEDAGTYQCRAANREDSLDASATIQVQVPPRFRKKP 305 >UniRef50_Q13332 Cluster: Receptor-type tyrosine-protein phosphatase S precursor; n=34; Craniata|Rep: Receptor-type tyrosine-protein phosphatase S precursor - Homo sapiens (Human) Length = 1948 Score = 111 bits (266), Expect = 3e-22 Identities = 132/604 (21%), Positives = 232/604 (38%), Gaps = 52/604 (8%) Query: 1473 VIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----------GK 1520 V++E ++ S P ++ + E + C G P P++TW++D G+ Sbjct: 124 VLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 183 Query: 1521 KLKTAKATYEN---RXXXXXXXXXXXXXXXYKCIAFNDHGEVETS----CVVGIQQKPVI 1573 + T+E+ R Y+C+A N G +S V +++ + Sbjct: 184 IKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRV 243 Query: 1574 TISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 + H++ G +T V G P P V W + L + + + +V+ Sbjct: 244 APRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLE 299 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 + ++K S+ YT A ++ G + V P P P++ E + S+TI W Sbjct: 300 LTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMV-TENTATSITITW---- 352 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 D G + Y + +++ + D Y I L+ N EY V A N +G + Sbjct: 353 DSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG--Q 410 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNG--GSPIIDYKVEIKQ 1808 SE +V +T P+ + ++ + W P E NG + Y +E + Sbjct: 411 GPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEH 470 Query: 1809 EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868 W+ + L + TY R+ A +G P + D I + P Q Sbjct: 471 PVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDG-PLS--DPIQVKTQQGVPGQ 527 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 P N + S+TL W+ P I Y + F+ +G ++ + +E Sbjct: 528 PMNLRAEARSETSITLSWSPPRQES---IIKYELLFR--EGDHGREVGRTFDPTTSYVVE 582 Query: 1929 NIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW- 1987 ++K E FR++A + G+ T VR + PS P ++ V S ++ SW Sbjct: 583 DLKPNTEYAFRLAARSPQGLGAFT--PVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWR 640 Query: 1988 -GTPEWDGGAPLLGYNIAIRDV--TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 PE GA L+GY++ R + EV + T + + L + Y I A Sbjct: 641 PPPPETHNGA-LVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAH 699 Query: 2045 NEIG 2048 E+G Sbjct: 700 TEVG 703 Score = 89.0 bits (211), Expect = 1e-15 Identities = 153/740 (20%), Positives = 282/740 (38%), Gaps = 59/740 (7%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343 E PP+ + ++ G + + P+P W K + + D S A Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGA 89 Query: 1344 SLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNI--------LEID 1393 L I+ + D +Y+ +N+ G V +T+L + P G PNI +E Sbjct: 90 VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERT 149 Query: 1394 SSSINICWDEPENTGN-STIIYYVVEYQEIDTT----EWISVKNITKTQTSIQN-LKTNS 1447 ++ +C +GN I + ++ +D + +++ T T I+ L+ S Sbjct: 150 RTATMLC----AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIES 205 Query: 1448 SY-----RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELT 1502 S ++ A N + +S Y + ++E + +P + P ++ +T Sbjct: 206 SEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNIT 265 Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 C+ G P P V W + + L R Y C+A + G +E Sbjct: 266 CVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSAN--YTCVAMSSLGVIEAV 323 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNI 1621 + ++ P + + +T + P V +Y K ++ D Y I Sbjct: 324 AQITVKSLPKAP-GTPMVTENTATS----ITITWDSGNPDPVSYYVIEYKSKSQDGPYQI 378 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREI 1678 T+ I L + + + A N+ G S VT P+ V R + Sbjct: 379 KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARML 438 Query: 1679 SRESVTIEWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 S ++ ++W+ P++ GL Y +E P N W K +VD + T + L E+ Sbjct: 439 SATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGN-WQK-HNVDDSLLT-TVGSLLEDE 495 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y RV+A VG + S+PI +KT VP + S+ ++W P + Sbjct: 496 TYTVRVLAFTSVG--DGPLSDPIQVKTQQGVPGQPMNLRAEARSET-SITLSWSPPRQES 552 Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTS 1853 II Y++ + +EG + ++ L NT Y FR+ AR+ G Sbjct: 553 ---IIKYEL-LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPV 608 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 + T+ + P Q V ST+ V+ + PE++ G+ + Y + ++ + G Sbjct: 609 VRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGA-LVGYSVRYRPL-GSEDP 666 Query: 1914 KIVTVGG---SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 + V G + + +E +++ + +RI+ V ES V + VPS P Sbjct: 667 EPKEVNGIPPTTTQILLEALEKWTQ--YRITTVAHTEVGPGPESSPVVVRTDEDVPSAPP 724 Query: 1971 APLEIRMVGSNIVMTSWGTP 1990 +E + + + W +P Sbjct: 725 RKVEAEALNATAIRVLWRSP 744 Score = 83.4 bits (197), Expect = 6e-14 Identities = 157/757 (20%), Positives = 287/757 (37%), Gaps = 71/757 (9%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161 E PP I ++Q G A+F + T GD R W K G ++ + D Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQAT-GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 88 Query: 1162 K-LKIYDCDLD-DAGEYSCEVGNS--------KCTAILTVEEPSINFTLRL-PEFILVP- 1209 L+I D Y C NS K T + + PS + + P+ +V Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT---------LIIRKCTE 1260 T L + ++TW+K ++ + I ++ T L I E Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEE 208 Query: 1261 DDQCEYTCVLLDA-----KSTTKLKV----EVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 DQ +Y CV ++ S L V EV P+ + I G +V + Sbjct: 209 TDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVA 268 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 P P +W+ ++ + P D ++ + D+ Y ++ G + Sbjct: 269 VGSPMPYVKWMQGAEDLT------PEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEA 322 Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISV 1430 +T+ P PG P + E ++SI I WD +GN + YYV+EY+ + Sbjct: 323 VAQITVKSLPKAPGTPMVTENTATSITITWD----SGNPDPVSYYVIEYKSKSQDGPYQI 378 Query: 1431 K-NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP-TVEKPL 1488 K +IT T+ SI L NS Y AVN + SE+ + ++ +P V+ + Sbjct: 379 KEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESV-VTRTGEQAPASAPRNVQARM 437 Query: 1489 KNITT---EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545 + TT + E +E + G + T + K ++ Sbjct: 438 LSATTMIVQWEEPVEPNGLIRGY-RVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDET 496 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-- 1603 + +AF G+ S IQ K + + + + + E +T + PP + Sbjct: 497 YTVRVLAFTSVGDGPLS--DPIQVKTQQGVPGQPMNLRAEARSETSIT--LSWSPPRQES 552 Query: 1604 VIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK- 1661 +I Y+ + ++ +E T TS + +++LK + + + A + G + ++ Sbjct: 553 IIKYELLFREGDHGREVGRTFDPTTSYV-VEDLKPNTEYAFRLAARSPQGLGAFTPVVRQ 611 Query: 1662 --VYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEP---DNNRWIK 1715 + KPS P V + ++ + W+ PP + L Y++ ++ P ++ + Sbjct: 612 RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSV-RYRPLGSEDPEPKE 670 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 V + ++ L + +Y +A VG ES P+V++T DVPS Sbjct: 671 VNGIPPTTTQILLEALEKWTQYRITTVAHTEVG--PGPESSPVVVRTDEDVPSAPPRKVE 728 Query: 1776 XXXIDNESVYITW-FPSEKNGGSPIIDYKVE-IKQEG 1810 ++ ++ + W P+ I Y+V ++ EG Sbjct: 729 AEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEG 765 Score = 82.6 bits (195), Expect = 1e-13 Identities = 81/309 (26%), Positives = 134/309 (43%), Gaps = 30/309 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K+PK Q G C+ P+P + W KG+++ + IE D Sbjct: 32 PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV--NSQRFETIEFD-ESAG 88 Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748 +VL+I ++ E Y VA N GE ++ L + ++ P P + + +V + Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-------DTHSITILK------PK 795 + + GNP P ITW K+ PV P+ S+G +T T ++ Sbjct: 149 TRTATMLCAASGNPDPEITWFKDFLPVD--PSASNGRIKQLRSETFESTPIRGALQIESS 206 Query: 796 KVKDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 + D+G Y A NS G+ +S A + V E E P F + G + + Sbjct: 207 EETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITC 266 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 +P+P + W + E ++P + + G N+ L +T+V DS +Y CVA +S G Sbjct: 267 VAVGSPMPYVKWMQGAEDLTPEDDMPV---GRNV-LELTDVK---DSANYTCVAMSSLGV 319 Query: 915 SSHGARVTI 923 A++T+ Sbjct: 320 IEAVAQITV 328 Score = 75.4 bits (177), Expect = 2e-11 Identities = 73/276 (26%), Positives = 120/276 (43%), Gaps = 21/276 (7%) Query: 717 GEASLPIVLKIK-TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 G L +VL + +EPP+ I+ K I G Q G+P+P +TW K K V Sbjct: 14 GPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 73 Query: 776 KALPTKS---DGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + ++ D ++ ++P + +DE VY A+NS G A +TV + + Sbjct: 74 NSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS-------ETITQNFD 884 P Q V+ T ++ + NP P ITW+++ + PS + ++ F+ Sbjct: 134 FPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFE 193 Query: 885 GENIELVITNVDS-EIDSGDYKCVASNSAG-KSSHGARVTI----DVEKVT-FVKHLQKS 937 I + S E D G Y+CVA+NSAG + S A + + +V +V L S Sbjct: 194 STPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMS 253 Query: 938 YETEEGKTVILECQT--SHTVSTKWYHNKKEISGMD 971 +E G V + C S KW ++++ D Sbjct: 254 HEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED 289 Score = 70.9 bits (166), Expect = 4e-10 Identities = 80/346 (23%), Positives = 140/346 (40%), Gaps = 39/346 (11%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ + + G F CQ G P+P++TW ++ + + + +D+ A L Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92 Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I+ + P D + CVA+N+ G E+ V A L+ D Sbjct: 93 IQPLRTPRDENVYECVAQNSVG------EITVHAKLT-----------------VLREDQ 129 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L P P+ + V+ + C P+P+I W + P + + Sbjct: 130 LPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRS 189 Query: 689 HMYCSV-----LKITNVKKFQEGTYTVVAVNREG-EASLPI---VLKIKTGEKEPPQV-I 738 + S L+I + ++ +G Y VA N G S P V +++ + P+ I Sbjct: 190 ETFESTPIRGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRELREVRRVAPRFSI 249 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798 P+ I+ G +V ++ VG+P P + W + + + T D +L+ VK Sbjct: 250 LPMSHEIM-PGGNVNITCVAVGSPMPYVKWMQGAEDL----TPEDDMPVGRNVLELTDVK 304 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 D YT A +S G+ E A ITV+ + P + N IT+ Sbjct: 305 DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITI 350 Score = 56.8 bits (131), Expect = 6e-06 Identities = 83/433 (19%), Positives = 164/433 (37%), Gaps = 38/433 (8%) Query: 1643 YTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE--SVTIEWKPPLDDGGLEL 1698 YT+ A + G + ++V + P P+ +R +R S+T+ W PP + + Sbjct: 497 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES---I 553 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 KY + E D+ R +V +Y ++ L N EY FR+ A++P G P+ Sbjct: 554 IKYELLFREGDHGR--EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLG---AFTPV 608 Query: 1759 V-IKTALDVPSXXXXXXXXXXIDNESVYITWF--PSEKNGGSPIIDYKVEIKQEGK---- 1811 V +T PS + + ++ ++W P E + G+ ++ Y V + G Sbjct: 609 VRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGA-LVGYSVRYRPLGSEDPE 667 Query: 1812 -KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPR 1870 K ++ L T Y+ A E+G P +S + + + P + PR Sbjct: 668 PKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPG-PESSPVVVRTDEDV-PSAPPR 725 Query: 1871 NFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEFKTVKG---KSWTKIVTVGGSVHEHC 1926 + ++ + W P I Y + + ++G + +I V + + Sbjct: 726 KVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWE 785 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPT---ESQSVRLEKHATVPSPPT---APLEIRMVGS 1980 ++ E + +I + E +++ + R + V L ++ Sbjct: 786 TDDTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPE 845 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAI--RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 ++ W P +LGY + D T +E + ++ + + TY+ Sbjct: 846 GSLLARWEPPAGTAEDQVLGYRLQFGREDSTPLATLEFPPSED---RYTASGVHKGATYV 902 Query: 2039 IRIYARNEIGLSE 2051 R+ AR+ GL E Sbjct: 903 FRLAARSRGGLGE 915 Score = 43.2 bits (97), Expect = 0.081 Identities = 56/252 (22%), Positives = 96/252 (38%), Gaps = 27/252 (10%) Query: 1682 SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV 1741 S+ W+PP ++ Y ++ D+ + + + Y +++ Y+FR+ Sbjct: 847 SLLARWEPPAGTAEDQVLGYRLQFGREDSTP-LATLEFPPSEDRYTASGVHKGATYVFRL 905 Query: 1742 IAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGS 1797 A++ G E A E I T P +V + W P +E+NG Sbjct: 906 AARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASA---GTVLLRWLPPVPAERNGA- 961 Query: 1798 PIIDYKVEIKQEGKKWKXXXXXXXXXAR--------IQKLSINTTYQFRIYARNEIGTSL 1849 I+ Y V +++ G A +Q L +T Y ++ A G Sbjct: 962 -IVKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPG- 1019 Query: 1850 PYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK---- 1905 P++ + L P+NF V SV L W P+ N SP T Y I++ Sbjct: 1020 PFSPP--VRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEFPD-NYNSP-TPYKIQYNGLTL 1075 Query: 1906 TVKGKSWTKIVT 1917 V G++ K++T Sbjct: 1076 DVDGRTTKKLIT 1087 >UniRef50_UPI0000F1EDBC Cluster: PREDICTED: similar to adlican; n=1; Danio rerio|Rep: PREDICTED: similar to adlican - Danio rerio Length = 1903 Score = 110 bits (265), Expect = 4e-22 Identities = 193/925 (20%), Positives = 354/925 (38%), Gaps = 92/925 (9%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDD 563 Q A I +KL G+ VQ C G PRP +TW + + A++ + Q + Sbjct: 926 QMRARITDDKLHTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHP 985 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 N T IR V +D G + C A NA HG++ + Sbjct: 986 N-GTFTIRNVHLQDRGQYLCSASNA------------------HGTDKMMVTLV------ 1020 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 +L +P S + + V G+ LL+C+ +P P+I+W+ ++ ++S Sbjct: 1021 ----VLAHVPRMTSPRHQDVTVYIGNTALLQCQAQGLPIPNISWMLPDRSML--RSVSNT 1074 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 + M + L+I G Y +A N G L + L+I P + ++ Sbjct: 1075 QQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSVRLQITA--LAPVIQEQRWEN 1132 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKD 799 + G + ++ G P PT+ W ++ +P + + + + ++ VKD Sbjct: 1133 YTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQFVNSNLFVFPNGTLFIRNPTVKD 1192 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G+Y A +S G+A+ S + V+ + + V + L + + Sbjct: 1193 SGIYECVAVSSVGMAKRSVNLQVK---RNSGSARILSTSAHSTDVHYGDQLSLNCSASGS 1249 Query: 860 PVPSITWYR-NNEIISPSETITQNFDG-ENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P I W +++ + + N L IT+V +E D G+Y C A N+AG Sbjct: 1250 PTPRIIWRTPAKKLVDSYYSFDRRMKVLSNGTLTITSV-TEQDEGEYLCAARNNAGDDYV 1308 Query: 918 GARVTIDVEKVTFVKHLQKS-YETEEGKTVILECQTS--HTVSTKW-YHNKKEISGM--D 971 +VT+ + K + H S ++ G + ++C S W + I+ + Sbjct: 1309 LLKVTV-MMKAAKIDHKSLSEHKVLYGGELKVDCIASGLPNPEVSWSLPDGTMINSVLSS 1367 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGV-----IKCIVKDQ----ETSTMLVVKETIPEFIRK 1022 + I+ R +VG+ C K+Q E + V P Sbjct: 1368 DKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNN 1427 Query: 1023 LQD-FEVKEKDVAILEVEINSETADVV-W-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 +V + AIL E V+ W D ++I P NKY G L+I T Sbjct: 1428 AYSVIKVTYGETAILNCSAKGEPTPVITWISPDKKVIVPMTNKYQISNDG---TLHIHKT 1484 Query: 1080 SVHDEGEYSCILRD-ESCTAEVTVVELP--PEIITRLQN-----QKVNKGNKATFEIELT 1131 + G Y+C+ R +V +VE+ P +I ++ + + + F+ + Sbjct: 1485 QKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFEHPGIIRKTAVRDQRVLFDCK-A 1543 Query: 1132 KGDALVR--WFKDGSEIQFSNHI--QLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183 G+ R W + + + + ++T+ + L I+ + D+ E C E G + Sbjct: 1544 NGNPFPRIIWLFPNNVVLPAPYYGSRITVH-RNGTLDIHAVRMSDSVELICIARNEFGET 1602 Query: 1184 KCTAILTVEEPSINFTLR--LPEFILVPANTDAYLTVEIP-DETLDVTW-YKKKSVIEDT 1239 K L V E I LR + I + L I + +TW + + Sbjct: 1603 KLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQG 1662 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV-EFPPKIVD-YEREY 1297 F+ L+I++ + D Y CV ++ + V +V P+I + Y Sbjct: 1663 TTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLL 1722 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKII-KKCKHTKPSIDSKSASLTIKKVENTDAG 1356 I G D+ L A P P W + S ++ + + + + +L+I + D G Sbjct: 1723 SIINGEDLHLDCVSDAHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRG 1782 Query: 1357 IYKLRLENNCGHADVEMNVTILDKP 1381 Y+ ++ N+ G + + ++V ++ P Sbjct: 1783 TYRCQISNDHGSSSLSVSVIVIAYP 1807 Score = 105 bits (251), Expect = 2e-20 Identities = 220/1002 (21%), Positives = 372/1002 (37%), Gaps = 109/1002 (10%) Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDG-DTH--SITILKP 794 + L ++ V G V L VG PRP +TW K + V + TK + H ++ Sbjct: 934 DKLHTVSVNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQRFEVHPNGTFTIRN 993 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 ++D G Y A N+ G + + V P R Q++TV T L Sbjct: 994 VHLQDRGQYLCSASNAHGTDKMMVTLVVLAHVPRMTSP-----RHQDVTVYIGNTALLQC 1048 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQN----FDGENIELVITNVDSEIDSGDYKCVASN 910 + P+P+I+W + + S + TQ +++ TN +D+G YKC+ASN Sbjct: 1049 QAQGLPIPNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNY---LDTGVYKCIASN 1105 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEIS 968 +AG R+ I + ++Y +G ++ C + + +W + S Sbjct: 1106 AAGADMLSVRLQITALAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTS----S 1161 Query: 969 GMDHR--EIIQEGRXXXXXXXXX----XXXDVGVIKCIVKDQ----ETSTMLVVKETIPE 1018 GM R + + D G+ +C+ + S L VK Sbjct: 1162 GMQLRPSQFVNSNLFVFPNGTLFIRNPTVKDSGIYECVAVSSVGMAKRSVNLQVKRNSGS 1221 Query: 1019 ---FIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRK- 1073 +V D L + S T ++W + K + Y F++R + Sbjct: 1222 ARILSTSAHSTDVHYGDQLSLNCSASGSPTPRIIWRTPAK--KLVDSYYSFDRRMKVLSN 1279 Query: 1074 --LYIRNTSVHDEGEYSCILR----DESCTAEVTVVELPPEIITR-LQNQKVNKGNKATF 1126 L I + + DEGEY C R D+ +VTV+ +I + L KV G + Sbjct: 1280 GTLTITSVTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSEHKVLYGGELKV 1339 Query: 1127 E-IELTKGDALVRW-FKDGSEIQ-FSNHIQLTIDGKKQ------KLKIYDCDLDDAGEYS 1177 + I + V W DG+ I + + TI K+ L + + + + G+Y+ Sbjct: 1340 DCIASGLPNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYT 1399 Query: 1178 C----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYK- 1231 C ++G + + V + I V A L E T +TW Sbjct: 1400 CYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCSAKGEPTPVITWISP 1459 Query: 1232 -KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPP 1288 KK ++ T K+ + +D TL I K + + YTC+ + + VEV+ FPP Sbjct: 1460 DKKVIVPMTNKYQISND---GTLHIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPP 1516 Query: 1289 KIVDYEREYRIKRGS--DVTLLVDYQAF--PQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343 I +E I++ + D +L D +A P P W+ + ++ + I ++ Sbjct: 1517 VINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNG 1576 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 +L I V +D+ N G + + + + + KP + + SI + Sbjct: 1577 TLDIHAVRMSDSVELICIARNEFGETKLHVKLEVTEDII---KPQLRNSPTDSIQL---- 1629 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR---AYAVNEVD 1460 G T + +E W ++ N TS+ T S + R A + E Sbjct: 1630 --TIGKPTTLNCSIEGNPAPQITW-TLPN----GTSLYQGTTFSRFHHRSDGALLIKEPS 1682 Query: 1461 ISDAS------ETTEYYKVIKETKIQS--PTVEKPLKNITTEPN-EDIELTCIFGGVPQP 1511 SDA + + T + + P + ++ + N ED+ L C+ P P Sbjct: 1683 SSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742 Query: 1512 KVTW-YRDGKKLKTAKATYE----NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS-CVV 1565 K+TW G L A+++ N Y+C NDHG S V+ Sbjct: 1743 KLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVSVI 1802 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW-YKNGNKLENDKE---YNI 1621 I P IT S +VG + P EV+W +G +L+ D + Y Sbjct: 1803 VIAYPPRIT-SGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQLKVDVQPRLYGN 1861 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 V++I S Y A N G+ S + V+ Sbjct: 1862 KHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYVF 1903 Score = 91.1 bits (216), Expect = 3e-16 Identities = 166/792 (20%), Positives = 298/792 (37%), Gaps = 73/792 (9%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V+ G+D+ L C V P P + W V N V ++H I NV Sbjct: 941 VNAGTDVQLPCNSVGEPRPLLTWTKVSTGAVMSTNTKVQ-RFEVHPN-GTFTIRNVHLQD 998 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPR 763 G Y A N G + + L + P++ P + + V G + +L Q G P Sbjct: 999 RGQYLCSASNAHGTDKMMVTLVVLA---HVPRMTSPRHQDVTVYIGNTALLQCQAQGLPI 1055 Query: 764 PTITWCKNNKPVKALPTKSDGD----THSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P I+W ++ + + + + +K D GVY A N+ G S Sbjct: 1056 PNISWMLPDRSMLRSVSNTQQKIMLLANGTLQIKQTNYLDTGVYKCIASNAAGADMLSVR 1115 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSET 878 + + P + R++ T+ + + P P++ W ++ + + PS+ Sbjct: 1116 LQITA-----LAPVIQEQRWENYTLSDGHAALIHCTANGAPNPTVRWVTSSGMQLRPSQF 1170 Query: 879 ITQN-FDGENIELVITNVDSEIDSGDYKCVASNSAG--KSSHGARVTIDVEKVTFVKHLQ 935 + N F N L I N + DSG Y+CVA +S G K S +V + + Sbjct: 1171 VNSNLFVFPNGTLFIRNPTVK-DSGIYECVAVSSVGMAKRSVNLQVKRNSGSARILSTSA 1229 Query: 936 KSYETEEGKTVILECQTSHTVSTK--WYHNKKEI----SGMDHR-EIIQEGRXXXXXXXX 988 S + G + L C S + + + W K++ D R +++ G Sbjct: 1230 HSTDVHYGDQLSLNCSASGSPTPRIIWRTPAKKLVDSYYSFDRRMKVLSNG---TLTITS 1286 Query: 989 XXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAI---LEVEINSE-- 1043 D G C ++ +++K T+ K+ + E V L+V+ + Sbjct: 1287 VTEQDEGEYLCAARNNAGDDYVLLKVTVMMKAAKIDHKSLSEHKVLYGGELKVDCIASGL 1346 Query: 1044 -TADVVWE-RDGEIIKP--KKNKYDFEKRGHIR----KLYIRNTSVHDEGEYSCILRD-- 1093 +V W DG +I +K + ++ LY+ + +EG+Y+C ++ Sbjct: 1347 PNPEVSWSLPDGTMINSVLSSDKNTIRAKRYVMFDNGTLYLNEVGMKEEGDYTCYAKNQM 1406 Query: 1094 --ESCTAEVTVVELPPEIITRLQNQ-KVNKGNKATFEIELTKGD--ALVRWFKDGSE--I 1146 + + V+ P I + KV G A KG+ ++ W + + Sbjct: 1407 GKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILNCS-AKGEPTPVITWISPDKKVIV 1465 Query: 1147 QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVG-NSKCTAILTVEEPSINFTLR 1201 +N Q++ DG L I+ ++G Y+C VG + K + + P + Sbjct: 1466 PMTNKYQISNDG---TLHIHKTQKINSGNYTCMARSVVGIDRKVVLVEVLVFPPVINGFE 1522 Query: 1202 LPEFILVPANTDAYLTVEIP---DETLDVTWYKKKSVIEDTEKF-TLISDVKKRTLIIRK 1257 P I A D + + + + W +V+ + + I+ + TL I Sbjct: 1523 HPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDIHA 1582 Query: 1258 CTEDDQCEYTCVLLDAKSTTKL--KVEVVE--FPPKIVDYERE-YRIKRGSDVTLLVDYQ 1312 D E C+ + TKL K+EV E P++ + + ++ G TL + Sbjct: 1583 VRMSDSVELICIARNEFGETKLHVKLEVTEDIIKPQLRNSPTDSIQLTIGKPTTLNCSIE 1642 Query: 1313 AFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 P P W + N + + +L IK+ ++DAG+Y+ N+ G V Sbjct: 1643 GNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALLIKEPSSSDAGLYRCVGRNSGGF--V 1700 Query: 1372 EMNVTILDKPSP 1383 E NVT++ P Sbjct: 1701 ERNVTLVSNRKP 1712 Score = 50.4 bits (115), Expect = 5e-04 Identities = 86/408 (21%), Positives = 141/408 (34%), Gaps = 53/408 (12%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V F+C+ G P P+I W ++ P+ + TL I V D+ C+A+ Sbjct: 1537 VLFDCKANGNPFPRIIWLFPNNVVLPAPYYGSRITVHRNGTLDIHAVRMSDSVELICIAR 1596 Query: 587 NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD 646 N G T+L V+ +++ DI++ P + + + Sbjct: 1597 NEFG----ETKLHVKLEVTE--------------------DIIK--PQLRNSPTDSIQLT 1630 Query: 647 EGSDILLECRLVAIPEPDIAW-LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 G L C + P P I W L G + S H L I Sbjct: 1631 IGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFS----RFHHRSDGALLIKEPSSSDA 1686 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRP 764 G Y V N G + L P++ S++ + GE + L +P P Sbjct: 1687 GLYRCVGRNSGGFVERNVTLV----SNRKPEITNQYSSLLSIINGEDLHLDCVSDAHPPP 1742 Query: 765 TITWCKNNKPVKALPTKSDGDTHSI----TI-LKPKKVKDEGVYTLKAENSEGIAETSAV 819 +TW + V L HS+ T+ + V D G Y + N G + S Sbjct: 1743 KLTWTLPSGVV--LSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSSLSVS 1800 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSITWYRNNEIISPSET 878 + V A PP + +T G + L R +P + W + + + Sbjct: 1801 VIVI------AYPPRITSGPAAVTYGRVGVALTLDCRSLASPRAEVVWQMPDGLQLKVDV 1854 Query: 879 ITQNFDGENIE---LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + + +++ ++ + S DSG YKC A N G S V + Sbjct: 1855 QPRLYGNKHLHPQGVLQIHSPSSRDSGVYKCTAKNVLGSDSRSTYVYV 1902 Score = 46.8 bits (106), Expect = 0.007 Identities = 89/438 (20%), Positives = 155/438 (35%), Gaps = 24/438 (5%) Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREY---RIKRGSDVTLL 1308 TL + + ++ +YTC + ++KV + V Y ++ G L Sbjct: 1384 TLYLNEVGMKEEGDYTCYAKNQMGKDEMKVHIKVLADAPVIRNNAYSVIKVTYGETAILN 1443 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 + P P WI K + K I S +L I K + ++G Y + G Sbjct: 1444 CSAKGEPTPVITWISPDKKVIVPMTNKYQI-SNDGTLHIHKTQKINSGNYTCMARSVVGI 1502 Query: 1369 ADVEMNVTILDKPSPPG---KPNILEIDSSSINICWDEPENTGNS--TIIYYVVEYQEID 1423 + V +L P P I+ + + + GN II+ + Sbjct: 1503 DRKVVLVEVLVFPPVINGFEHPGIIRKTAVRDQRVLFDCKANGNPFPRIIWLFPNNVVLP 1562 Query: 1424 TTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETKIQS 1481 + S + + T I ++ + S A NE ET + K+ + E I+ Sbjct: 1563 APYYGSRITVHRNGTLDIHAVRMSDSVELICIARNEF-----GETKLHVKLEVTEDIIKP 1617 Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKL--KTAKATYENRXXXXXX 1538 P +I + L C G P P++TW +G L T + + +R Sbjct: 1618 QLRNSPTDSIQLTIGKPTTLNCSIEGNPAPQITWTLPNGTSLYQGTTFSRFHHRSDGALL 1677 Query: 1539 XX--XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y+C+ N G VE + + +KP IT + G++ + V Sbjct: 1678 IKEPSSSDAGLYRCVGRNSGGFVERNVTLVSNRKPEITNQYSSLLSIIN-GEDLHLDCVS 1736 Query: 1597 EGIPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + PPP++ W +G L + + + I Y + SN G+SS Sbjct: 1737 DAHPPPKLTWTLPSGVVLSRAQSSGRHSVLNNGTLSIHRTSVYDRGTYRCQISNDHGSSS 1796 Query: 1656 VEVTLKVYDKPSK-PEGP 1672 + V++ V P + GP Sbjct: 1797 LSVSVIVIAYPPRITSGP 1814 Score = 38.7 bits (86), Expect = 1.7 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 9/118 (7%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 + +E +YT Y + ++ + D++ V K ++ + ++ + G T C Sbjct: 1392 MKEEGDYTCYAKNQMGK--DEMKVHIKVLADAPVIRNNAYSVIKVTY---GETAILNCSA 1446 Query: 534 EGYPRPQITWFR-QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 +G P P ITW +I P + Y N TL I + ++G +TC+A++ G Sbjct: 1447 KGEPTPVITWISPDKKVIVPMTN---KYQISNDGTLHIHKTQKINSGNYTCMARSVVG 1501 >UniRef50_Q172S1 Cluster: Stretchin-mlck; n=1; Aedes aegypti|Rep: Stretchin-mlck - Aedes aegypti (Yellowfever mosquito) Length = 712 Score = 110 bits (265), Expect = 4e-22 Identities = 111/434 (25%), Positives = 179/434 (41%), Gaps = 52/434 (11%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ + L+ + P GSTV+ C + G P + WF+ I+ S + + + +L Sbjct: 284 PLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAK-HTFKVSEGLLSLE 341 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 I V D G ++C+ KN G S++T + V Sbjct: 342 IVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFES----------------------- 378 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 + IPPTF K Y +I+LECR+ P P+IAW+ GE I+P + +D Sbjct: 379 KPIPPTFISI-KETYSLHSDEIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGT 437 Query: 690 MYCSVLKITNVKKFQEGTYTVVA------------VNREGEASLPIVLKIKTGEKEP--P 735 C ++ IT + GTYT A V G+ + + + P P Sbjct: 438 --CKLI-ITKPGEEDSGTYTCEAESGGCSDAISHNVQFVGKEKIMMERTHSYYHRNPNLP 494 Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITI 791 + L + G ++ L +V GN + W K+ VK P K SDG Sbjct: 495 HFYQSLADYSIPSGGNICLVVEVQGNCE--VQWFKDKYEVKGRPPKFRFYSDGTGVFALC 552 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQ-EITVKEKGT 849 + + G YT +A N+ G AE+S+ + V P + A+PP+F+ R Q EI +++ Sbjct: 553 ITAATMDASGKYTCRATNAFGKAESSSNVDVINPNAIKGAKPPIFMARPQPEIKIRQGQE 612 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 I + ++ +P P I W + + I+ + + + I I D G Y VA Sbjct: 613 ISMAFKIIGDPKPKIQWMKGTKDITNAARTVKEVHNDFIRFSIKEA-LTTDEGAYFIVAR 671 Query: 910 NSAGKSSHGARVTI 923 N G +VT+ Sbjct: 672 NRYGIDRCFTKVTV 685 Score = 88.2 bits (209), Expect = 2e-15 Identities = 86/358 (24%), Positives = 142/358 (39%), Gaps = 26/358 (7%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D+ Y+ ++ K E V + E + + P F+ ++ ++ + EC+V G Sbjct: 349 DQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFIS-IKETYSLHSDEIVLECRVRG 407 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 PRP I W + I P ++ Y D L+I + ED+GT+TC A+ +G S Sbjct: 408 SPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAE--SGGCSDA 465 Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 V+ G E + ++ P F + + G +I C Sbjct: 466 ISHNVQFV----GKE-KIMMERTHSYYHRNPNL-----PHFYQSLADYSIPSGGNI---C 512 Query: 656 RLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714 +V + ++ W FK + V SD L IT G YT A N Sbjct: 513 LVVEVQGNCEVQW-FKDKYEVKGRPPKFRFYSD-GTGVFALCITAATMDASGKYTCRATN 570 Query: 715 REGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC 769 G+A + + G K P + P + +RQG+ + ++ +++G+P+P I W Sbjct: 571 AFGKAESSSNVDVINPNAIKGAKPPIFMARPQPEIKIRQGQEISMAFKIIGDPKPKIQWM 630 Query: 770 KNNKPV-KALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 K K + A T + I +K DEG Y + A N GI +TV+ P Sbjct: 631 KGTKDITNAARTVKEVHNDFIRFSIKEALTTDEGAYFIVARNRYGIDRCFTKVTVKHP 688 Score = 79.4 bits (187), Expect = 1e-12 Identities = 69/257 (26%), Positives = 109/257 (42%), Gaps = 26/257 (10%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP +I LKS +G +V L+ + G P T+ W K+ P++ + + + L+ Sbjct: 283 PPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLSLE 341 Query: 794 PKKV--KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 V D+G Y+ +N G TS + V E E PP FI+ +E I Sbjct: 342 IVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFIS-IKETYSLHSDEIV 400 Query: 852 LVARVTRNPVPSITWYRNNEIISPSETITQ--NFDGENIELVITNVDSEIDSGDYKCVAS 909 L RV +P P+I W ++ E I P + Q + DG +L+IT E DSG Y C A Sbjct: 401 LECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADG-TCKLIITKPGEE-DSGTYTCEAE 458 Query: 910 NS--AGKSSHGARVTIDVEKVTF------------VKHLQKS---YETEEGKTVILECQT 952 + + SH + + EK+ + H +S Y G + L + Sbjct: 459 SGGCSDAISHNVQF-VGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEV 517 Query: 953 SHTVSTKWYHNKKEISG 969 +W+ +K E+ G Sbjct: 518 QGNCEVQWFKDKYEVKG 534 Score = 77.4 bits (182), Expect = 4e-12 Identities = 73/309 (23%), Positives = 125/309 (40%), Gaps = 26/309 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP K++ +GS + L C + P + W G I + + + Sbjct: 283 PPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLS-- 339 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI-KTGEKEP-PQVIEPLKSMIVRQGE 750 L+I NV +G Y+ + N+ GE S +K+ ++ E +P P +K + Sbjct: 340 --LEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSD 397 Query: 751 SVILSAQVVGNPRPTITWCKNNK---PVKALPTKSDGD-THSITILKPKKVKDEGVYTLK 806 ++L +V G+PRP I W K+ + P D T + I KP + +D G YT + Sbjct: 398 EIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGE-EDSGTYTCE 456 Query: 807 AEN---SEGIAETSAVITVEEPTEE--------NAEPPLFINRFQEITVKEKGTIKLVAR 855 AE+ S+ I+ + E+ E N P F + ++ G I LV Sbjct: 457 AESGGCSDAISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVE 516 Query: 856 VTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V N + W+++ E+ DG + + + SG Y C A+N+ GK Sbjct: 517 VQGN--CEVQWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNAFGK 574 Query: 915 SSHGARVTI 923 + + V + Sbjct: 575 AESSSNVDV 583 Score = 70.1 bits (164), Expect = 6e-10 Identities = 93/395 (23%), Positives = 160/395 (40%), Gaps = 47/395 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 P I L+ + L I+ V W +DG I+ K K+ F+ + L I Sbjct: 284 PLIISHLKSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIE-KSAKHTFKVSEGLLSLEI 342 Query: 1077 RNTSVHDEGEYSCILRDE----SCTAEVTVVE------LPPEIITRLQNQKVNKGNKATF 1126 N D+GEYSCI++++ S + V V E +PP I+ + ++ ++ Sbjct: 343 VNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHS-DEIVL 401 Query: 1127 EIELTKGDAL-VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 E + + W KDG I + Q KL I +D+G Y+CE + Sbjct: 402 ECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGG 461 Query: 1185 CTAILT-----------VEEPSINFTLR---LPEFIL------VPANTDAYLTVEIPDET 1224 C+ ++ + E + ++ R LP F +P+ + L VE+ Sbjct: 462 CSDAISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEVQGNC 521 Query: 1225 LDVTWYKKKSVIEDTE-KFTLISD-VKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLK 1280 +V W+K K ++ KF SD L I T D +YTC +A K+ + Sbjct: 522 -EVQWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNAFGKAESSSN 580 Query: 1281 VEVVE-------FPPKIVDYER-EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK 1332 V+V+ PP + + E +I++G ++++ P+P +W+ +K I Sbjct: 581 VDVINPNAIKGAKPPIFMARPQPEIKIRQGQEISMAFKIIGDPKPKIQWMKGTKDITNAA 640 Query: 1333 HTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 T + + +IK+ TD G Y + N G Sbjct: 641 RTVKEVHNDFIRFSIKEALTTDEGAYFIVARNRYG 675 Score = 61.7 bits (143), Expect = 2e-07 Identities = 60/261 (22%), Positives = 107/261 (40%), Gaps = 17/261 (6%) Query: 1420 QEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 +E D + W SV ++ T+ + S + K + + + E TE + ++ + Sbjct: 217 EEFDPSVWKSVDDLETQLKNSEEETKKAKAKEAKEASKESSRRESTHEMTERERDLEWQR 276 Query: 1479 ----IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-KTAKATY---E 1530 ++ P + LK+ ++LTC G P V W++DG + K+AK T+ E Sbjct: 277 QRQLMRPPLIISHLKSRAAPKGSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSE 335 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI----QQKPVITISNEDIKQKHKV 1586 Y CI N +GE TS V + + KP I + IK+ + + Sbjct: 336 GLLSLEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKP-IPPTFISIKETYSL 394 Query: 1587 -GDEWLVTAVIEGIPPPEVIWYKNGNK-LENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 DE ++ + G P P + W K+G + DK + T + I + S YT Sbjct: 395 HSDEIVLECRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYT 454 Query: 1645 IEASNTAGTSSVEVTLKVYDK 1665 EA + + ++ ++ K Sbjct: 455 CEAESGGCSDAISHNVQFVGK 475 Score = 54.8 bits (126), Expect = 2e-05 Identities = 68/288 (23%), Positives = 109/288 (37%), Gaps = 38/288 (13%) Query: 931 VKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXX 988 + HL KS +G TV L C S ++ +W+ + I H + EG Sbjct: 287 ISHL-KSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEG-LLSLEIVN 344 Query: 989 XXXXDVGVIKCIVKDQ--ETSTMLVVK-------ETIPEFIRKLQDFEVKEKDVAILEVE 1039 D G CI+K++ ETST VK + IP +++ D +LE Sbjct: 345 VDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSDEIVLECR 404 Query: 1040 IN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT- 1097 + S ++ W +DGE I P ++ KL I D G Y+C C+ Sbjct: 405 VRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGGCSD 464 Query: 1098 ----------AEVTVVELP----------PEIITRLQNQKVNKGNKATFEIELTKGDALV 1137 E ++E P L + + G +E+ +G+ V Sbjct: 465 AISHNVQFVGKEKIMMERTHSYYHRNPNLPHFYQSLADYSIPSGGNICLVVEV-QGNCEV 523 Query: 1138 RWFKDGSEIQ-FSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGNS 1183 +WFKD E++ + DG L I +D +G+Y+C N+ Sbjct: 524 QWFKDKYEVKGRPPKFRFYSDGTGVFALCITAATMDASGKYTCRATNA 571 Score = 53.2 bits (122), Expect = 8e-05 Identities = 47/173 (27%), Positives = 73/173 (42%), Gaps = 10/173 (5%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 PP II+ L+++ KG+ ++ VRWFKDG+ I+ S + L+I Sbjct: 283 PPLIISHLKSRAAPKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEGLLSLEI 342 Query: 1166 YDCDLDDAGEYSCEVGNSKC-TAILTVEEPSINFTLR-LPEFILVPANTDAYLTVEIPDE 1223 + D D GEYSC + N T+ T + +F + +P + T + + EI E Sbjct: 343 VNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSLHSDEIVLE 402 Query: 1224 TL-------DVTWYKKKSVIEDTEKFTLISDVKKR-TLIIRKCTEDDQCEYTC 1268 ++ W K I +K+ LII K E+D YTC Sbjct: 403 CRVRGSPRPNIAWIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTC 455 Score = 51.6 bits (118), Expect = 2e-04 Identities = 46/182 (25%), Positives = 76/182 (41%), Gaps = 12/182 (6%) Query: 1209 PANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 P + LT I + V W+K + IE + K T +L I DQ EY+C Sbjct: 296 PKGSTVKLTCTISGPGITVRWFKDGNPIEKSAKHTFKVSEGLLSLEIVNVDYSDQGEYSC 355 Query: 1269 VL--LDAKSTTKLKVEVVE------FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE 1320 ++ + +++T V+V E PP + + Y + ++ L + P+PN Sbjct: 356 IIKNKNGETSTSTTVKVYESFESKPIPPTFISIKETYSL-HSDEIVLECRVRGSPRPNIA 414 Query: 1321 WIVNSK-IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLEN-NCGHADVEMNVTIL 1378 WI + + II K+ + + L I K D+G Y E+ C A + NV + Sbjct: 415 WIKDGEYIIPGDKYEQYDHADGTCKLIITKPGEEDSGTYTCEAESGGCSDA-ISHNVQFV 473 Query: 1379 DK 1380 K Sbjct: 474 GK 475 Score = 44.4 bits (100), Expect = 0.035 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 3/107 (2%) Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 +P + IS+ + K G +T I G P V W+K+GN +E ++ E Sbjct: 282 RPPLIISHLKSRAAPK-GSTVKLTCTISG-PGITVRWFKDGNPIEKSAKHTFKVSEGLLS 339 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK-PSKPEGPVIM 1675 + I + S +Y+ N G +S T+KVY+ SKP P + Sbjct: 340 LEIVNVDYSDQGEYSCIIKNKNGETSTSTTVKVYESFESKPIPPTFI 386 >UniRef50_UPI00005BDC8C Cluster: PREDICTED: similar to hemicentin; n=1; Bos taurus|Rep: PREDICTED: similar to hemicentin - Bos taurus Length = 2756 Score = 110 bits (264), Expect = 5e-22 Identities = 134/575 (23%), Positives = 229/575 (39%), Gaps = 65/575 (11%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE-EIV--PDENISVAIESDMH 689 PP+ S +G + +LEC +P P + W ++G+ E++ P+++IS Sbjct: 1147 PPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIW-YRGDLEMILAPEDSIS-------- 1197 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 +L+I V++ G YT AVN G+AS I L++ PQ++E + + V G Sbjct: 1198 ---GMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVG----HAPQLLELPQDVTVELG 1250 Query: 750 ESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKA 807 S +L+ + G+P PTITW + +++P+ P G S + + +D+ +Y +A Sbjct: 1251 RSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQALYVCEA 1310 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV-TRNPVPSITW 866 EN G + A + V PP + + V E+ + L V P P W Sbjct: 1311 ENVFGKVQAEAYLLV-----TGHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRW 1365 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + + P + DG ++ L ++ D+G Y CV SN+AG SH V + V+ Sbjct: 1366 LKAGMPLPPGSRHSIRADG-SLHLDQALLE---DAGRYSCVVSNTAG--SHHRDVQLVVQ 1419 Query: 927 KVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-HREIIQEGRXXX 983 ++ + T EG L C S T + W ++ D H + ++G Sbjct: 1420 VPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVSKDG---T 1476 Query: 984 XXXXXXXXXDVGVIKCIVKDQ---ETSTMLVVKETIPEFI-------RKLQDFEVKEKDV 1033 D G C + + M + T P + K K D Sbjct: 1477 LVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAKAGDE 1536 Query: 1034 AILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 L+ E +V W +D + P +++ G L++ V D G Y C Sbjct: 1537 VTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPG---SLHLAQAQVSDSGLYECTAS 1593 Query: 1093 DESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQF 1148 + + +A + V++PP++ + KV G + + V W KDG Sbjct: 1594 NPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPRVTWSKDG----- 1648 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 + L +G + + AG Y CE +S Sbjct: 1649 ---VALRGEGPEGSVHFAAIQTSHAGTYRCEASSS 1680 Score = 100 bits (239), Expect = 5e-19 Identities = 153/732 (20%), Positives = 275/732 (37%), Gaps = 76/732 (10%) Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +I K +EGTY AV+R G + + TG PPQ++ P+ ++ V GE+ ILS Sbjct: 932 EIPRASKAEEGTYECTAVSRAGTGRAKTQIVV-TGP--PPQLV-PVPNVTVSPGETAILS 987 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 V+ +TW ++ + + A + ++ D G Y A NS G+ Sbjct: 988 CLVLSEAPYNLTWVRDWRVLSASTGRVTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTR 1047 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 S + V E + + R Q + + +++ + P P I+W R + Sbjct: 1048 ASVWLLVREAPQVSIH-----TRSQRFS--QGMEVRVRCSASGYPAPHISWSREGRALQE 1100 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 + + G L+I V E D+G Y C A+N G+ VT+ V + Sbjct: 1101 DSRVRVDAQG---TLIIQGVAPE-DAGSYSCQAANEIGRDEE--TVTLYYTDPPSVSAVN 1154 Query: 936 KSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXD 993 +G+ +LEC+ + + WY E+ I D Sbjct: 1155 GVVLAAKGEEAVLECEATGVPPPRVIWYRGDLEMILAPEDSI-----SGMLRIPVVRERD 1209 Query: 994 VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVW 1049 GV C ++ ++ + P+ + QD V+ A+L + W Sbjct: 1210 AGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITW 1269 Query: 1050 ER--DGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDESCTAEVTVV 1103 R D + ++ + G L+ + D+ Y C + A + V Sbjct: 1270 HRGDDQPLGLRPGSRTGWPDSG---VLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVT 1326 Query: 1104 -ELPPEIITRLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSEIQFSNHIQLTIDGKK 1160 +PP+I + +V + + + G RW K G + + + DG Sbjct: 1327 GHVPPQIASSAPTVRVLERQPVSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRADG-- 1384 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN---TDAYLT 1217 L + L+DAG YSC V N+ + + +++P I A T+ + Sbjct: 1385 -SLHLDQALLEDAGRYSCVVSNTAGS-----HHRDVQLVVQVPPRIQPTATHHITNEGVP 1438 Query: 1218 VEIP-----DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 +P T +TW K+ + + + +S K TL+I + + D Y C + Sbjct: 1439 ASLPCVASGVPTPTITWTKETNALASRDPHYNVS--KDGTLVIPRPSVQDAGAYVCTATN 1496 Query: 1273 AKSTTKLKVEV-VEFPPKIV-----DYEREYRI--KRGSDVTLLVDYQAFPQPNDEWIVN 1324 A + ++ + V P+I+ + ++ R+ K G +VTL + Q P P W Sbjct: 1497 AVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAKAGDEVTLDCEAQGSPPPLVTW--- 1553 Query: 1325 SKIIKKCKHTKPSIDS----KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 K +H P D SL + + + +D+G+Y+ N G A + + Sbjct: 1554 ---TKDSRHMLPITDRHHLLPPGSLHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVP 1610 Query: 1381 PSPPGKPNILEI 1392 P P +L++ Sbjct: 1611 PQVQPGPRVLKV 1622 Score = 91.9 bits (218), Expect = 2e-16 Identities = 110/472 (23%), Positives = 188/472 (39%), Gaps = 46/472 (9%) Query: 632 IPPTFS---KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 +PPT + P+ G + LEC P P ++W +G +V + Sbjct: 2209 VPPTIEGTGEGPRVVKAVAGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGG-- 2266 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 VL + ++ + G Y+ VA + GEA L ++++ + V E L + Sbjct: 2267 ----GVLSLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQL--LVAEGLGQVTTLV 2320 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILKPKKVKDEGVYTL 805 G+S+ L G+P PTI W +N P + LP S+G T I ++ + G++ Sbjct: 2321 GQSLYLPCYASGSPVPTIQWLQNGHPAEELPGVHVTSEGTTLHIDHVE---LGHAGLFAC 2377 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A N G A ++V E P + I + IT + L T P PS+ Sbjct: 2378 QATNEAGTAAAEVELSVHEL------PSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLR 2431 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W+++ ++ S G +++ I VD + D G Y CVA+N AG+S + + V Sbjct: 2432 WWKDGVALAAS--------GGSLQ--IEKVDLK-DEGTYTCVATNLAGESRKEVILRVLV 2480 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXX 983 + K+ E +V LEC S W+ ++ IS D + +GR Sbjct: 2481 PPNIEPGLVNKA--VLENASVTLECLASGVPPPDISWFKGRQPISAWDRAMVSTDGRVLL 2538 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLV--VKETIPEFIR---KLQDFEVKEKDVAILEV 1038 D G +C+ + ST L ++ +P I L + V + Sbjct: 2539 IEQAQLS--DAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 + + ++W +DG + + R L + + V D G YSC+ Sbjct: 2597 AAGAPSPMLMWLKDGNPVSTAGTA-GLQVFPGGRVLMLASARVSDSGSYSCV 2647 Score = 91.5 bits (217), Expect = 2e-16 Identities = 158/780 (20%), Positives = 299/780 (38%), Gaps = 77/780 (9%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 ++ G PP P V G +L C +++ ++ W+ + ++ V +D Sbjct: 962 VVTGPPPQLVPVPNVT-VSPGETAILSCLVLSEAPYNLTWV-RDWRVLSASTGRVTQLAD 1019 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + L++ N G Y +A N G + L ++ E PQV +S Sbjct: 1020 LS-----LEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVR----EAPQVSIHTRSQRFS 1070 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 QG V + G P P I+W + + ++ ++ D I++ +D G Y+ +A Sbjct: 1071 QGMEVRVRCSASGYPAPHISWSREGRALQE-DSRVRVDAQGTLIIQGVAPEDAGSYSCQA 1129 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 N G E + + +P +A + + E V E T P P + WY Sbjct: 1130 ANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLE-------CEATGVPPPRVIWY 1182 Query: 868 RNN--EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 R + I++P ++I+ ++ V E D+G Y C A N G +S A + ++V Sbjct: 1183 RGDLEMILAPEDSISG--------MLRIPVVRERDAGVYTCRAVNELGDAS--AEIRLEV 1232 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQ-TSHTVST-KWYHNKKEISGMDHREIIQEGRXXX 983 + L + E G++ +L C+ T H + T W+ + G+ Sbjct: 1233 GHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292 Query: 984 XXXXXXXXXDVGVIKCIVKD-----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE- 1037 D + C ++ Q + +LV P+ V E+ L Sbjct: 1293 LFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVSLPC 1352 Query: 1038 -VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 V + W + G + P +++ G L++ + D G YSC++ + + Sbjct: 1353 IVLAGRPRPERRWLKAGMPLPPG-SRHSIRADG---SLHLDQALLEDAGRYSCVVSNTAG 1408 Query: 1097 TAE---VTVVELPPEIITRLQNQKVNKGNKATFE-IELTKGDALVRWFKDGSEIQFSN-H 1151 + VV++PP I + N+G A+ + + W K+ + + + H Sbjct: 1409 SHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPH 1468 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 ++ DG L I + DAG Y C N+ + + S+N R+ A+ Sbjct: 1469 YNVSKDGT---LVIPRPSVQDAGAYVCTATNAVGFSSQEMRL-SVNTKPRILVNGSHEAD 1524 Query: 1212 TDAYLTVEIPDE-TLD----------VTWYK-KKSVIEDTEKFTLISDVKKRTLIIRKCT 1259 +T + DE TLD VTW K + ++ T++ L+ +L + + Sbjct: 1525 KPLRVTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPP---GSLHLAQAQ 1581 Query: 1260 EDDQCEYTCVLLD-AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPN 1318 D Y C + A S T+ + V+ PP++ R ++ G V L + P+P Sbjct: 1582 VSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDLNCVAEGSPEPR 1641 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 W + ++ + S+ ++ + AG Y+ ++ G E+++ +L Sbjct: 1642 VTWSKDGVALRG--------EGPEGSVHFAAIQTSHAGTYRCEASSSAGVDAWELDLRVL 1693 Score = 90.6 bits (215), Expect = 4e-16 Identities = 160/788 (20%), Positives = 276/788 (35%), Gaps = 54/788 (6%) Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSH 954 S+ + G Y+C A + AG ++ + V + G+T IL C + Sbjct: 937 SKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVP--VPNVTVSPGETAILSCLVLSEA 994 Query: 955 TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTML 1010 + W + + +S R + + D G +C+ + S L Sbjct: 995 PYNLTWVRDWRVLSASTGR--VTQLADLSLEVRNTTPSDGGRYQCMASNSNGVTRASVWL 1052 Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGH 1070 +V+E I + +V + + W R+G ++ + ++ + +G Sbjct: 1053 LVREAPQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQ-EDSRVRVDAQG- 1110 Query: 1071 IRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL---PPEIITRLQNQKVNKGNKATFE 1127 L I+ + D G YSC +E E TV PP + KG +A E Sbjct: 1111 --TLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLE 1168 Query: 1128 IELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--K 1184 E T V W++ E+ I D L+I DAG Y+C N Sbjct: 1169 CEATGVPPPRVIWYRGDLEM-----ILAPEDSISGMLRIPVVRERDAGVYTCRAVNELGD 1223 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFT 1243 +A + +E L LP+ + V A L L +TW++ + Sbjct: 1224 ASAEIRLEVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGS 1283 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV---EFPPKIVDYEREYRIK 1300 L +DQ Y C + + + ++ PP+I R+ Sbjct: 1284 RTGWPDSGVLFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVL 1343 Query: 1301 RGSDVTL-LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 V+L + P+P W+ + ++ SI + SL + + DAG Y Sbjct: 1344 ERQPVSLPCIVLAGRPRPERRWLKAGMPLPP--GSRHSIRA-DGSLHLDQALLEDAGRYS 1400 Query: 1360 LRLENNCG--HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 + N G H DV++ V + + P +I + C T T + Sbjct: 1401 CVVSNTAGSHHRDVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTIT---WTK 1457 Query: 1418 EYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 E + + + N++K T I + + A N V S + Sbjct: 1458 ETNALASRD--PHYNVSKDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRI 1515 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK--TAKATYENRXX 1534 S +KPL+ +T + +++ L C G P P VTW +D + + T + Sbjct: 1516 LVNGSHEADKPLR-VTAKAGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPPGS 1574 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y+C A N G ++ +Q P + +K VG+ + Sbjct: 1575 LHLAQAQVSDSGLYECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVL--VGEAVDLNC 1632 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 V EG P P V W K+G L + + ++ SH+ Y EAS++AG Sbjct: 1633 VAEGSPEPRVTWSKDGVALRGEGP--------EGSVHFAAIQTSHAGTYRCEASSSAGVD 1684 Query: 1655 SVEVTLKV 1662 + E+ L+V Sbjct: 1685 AWELDLRV 1692 Score = 88.6 bits (210), Expect = 2e-15 Identities = 137/702 (19%), Positives = 259/702 (36%), Gaps = 54/702 (7%) Query: 1008 TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFE 1066 T +VV P+ + + + V + AIL + SE ++ W RD ++ + Sbjct: 959 TQIVVTGPPPQLV-PVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSASTGRVT-- 1015 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNK 1123 + + L +RNT+ D G Y C+ + + +V V P++ ++Q+ ++G + Sbjct: 1016 QLADL-SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQRFSQGME 1074 Query: 1124 ATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178 + A + W ++G +Q + +++ G L I +DAG YSC Sbjct: 1075 VRVRCSASGYPAPHISWSREGRALQEDSRVRVDAQGT---LIIQGVAPEDAGSYSCQAAN 1131 Query: 1179 EVGNSKCTAILT-VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVI 1236 E+G + T L + PS++ + +L +A L E V WY+ Sbjct: 1132 EIGRDEETVTLYYTDPPSVS---AVNGVVLAAKGEEAVLECEATGVPPPRVIWYRG---- 1184 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER 1295 D E D L I E D YTC ++ ++ + V P++++ + Sbjct: 1185 -DLEMILAPEDSISGMLRIPVVRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELPQ 1243 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + ++ G L P P W + + S L + V D Sbjct: 1244 DVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGVLFFESVVPEDQ 1303 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYY 1415 +Y EN G E + + P +I SS+ + E + I Sbjct: 1304 ALYVCEAENVFGKVQAEAYLLVTGHVPP-------QIASSAPTVRVLERQPVSLPCI--- 1353 Query: 1416 VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA--SETT-EYYK 1472 V+ + W+ + S +++ + S + + S T +++ Sbjct: 1354 VLAGRPRPERRWLKA-GMPLPPGSRHSIRADGSLHLDQALLEDAGRYSCVVSNTAGSHHR 1412 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--E 1530 ++ P ++ + T L C+ GVP P +TW ++ L + Y Sbjct: 1413 DVQLVVQVPPRIQPTATHHITNEGVPASLPCVASGVPTPTITWTKETNALASRDPHYNVS 1472 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI-----SNEDIKQKHK 1585 Y C A N G + + KP I + +++ ++ K Sbjct: 1473 KDGTLVIPRPSVQDAGAYVCTATNAVGFSSQEMRLSVNTKPRILVNGSHEADKPLRVTAK 1532 Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 GDE + +G PPP V W K+ + D+ + + + + + + S S Y Sbjct: 1533 AGDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLL----PPGSLHLAQAQVSDSGLY 1588 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 ASN AG+++ L+V P GP +++ + E+V + Sbjct: 1589 ECTASNPAGSATQYYILRVQVPPQVQPGPRVLKVLVGEAVDL 1630 Score = 80.2 bits (189), Expect = 6e-13 Identities = 108/511 (21%), Positives = 200/511 (39%), Gaps = 36/511 (7%) Query: 1181 GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE-DT 1239 G +K ++T P + + +P + P T + + + ++TW + V+ T Sbjct: 955 GRAKTQIVVTGPPPQL---VPVPNVTVSPGETAILSCLVLSEAPYNLTWVRDWRVLSAST 1011 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYR 1298 + T ++D+ +L +R T D Y C+ ++ T+ V + V P++ + R R Sbjct: 1012 GRVTQLADL---SLEVRNTTPSDGGRYQCMASNSNGVTRASVWLLVREAPQVSIHTRSQR 1068 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +G +V + +P P+ W + +++ + +D++ +L I+ V DAG Y Sbjct: 1069 FSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVR--VDAQG-TLIIQGVAPEDAGSY 1125 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE 1418 + N G + + + D PS ++ + E +I+Y + Sbjct: 1126 SCQAANEIGRDEETVTLYYTDPPSVSAVNGVVLAAKGEEAVLECEATGVPPPRVIWYRGD 1185 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 + I E S+ + + I ++ + + AVNE + DAS ++ E Sbjct: 1186 LEMILAPE-DSISGMLR----IPVVRERDAGVYTCRAVNE--LGDASA-----EIRLEVG 1233 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKL---KTAKATYENRXX 1534 +E P +++T E L C G P P +TW+R D + L ++ + + Sbjct: 1234 HAPQLLELP-QDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGSRTGWPDSGV 1292 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEV--ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C A N G+V E +V P I S ++ + L Sbjct: 1293 LFFESVVPEDQALYVCEAENVFGKVQAEAYLLVTGHVPPQIASSAPTVRVLERQPVS-LP 1351 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 V+ G P PE W K G L ++I + + + + +Y+ SNTAG Sbjct: 1352 CIVLAGRPRPERRWLKAGMPLPPGSRHSI---RADGSLHLDQALLEDAGRYSCVVSNTAG 1408 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESV 1683 + +V L V P P I+ E V Sbjct: 1409 SHHRDVQLVVQVPPRIQ--PTATHHITNEGV 1437 Score = 77.8 bits (183), Expect = 3e-12 Identities = 114/550 (20%), Positives = 204/550 (37%), Gaps = 45/550 (8%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTV 1191 + WFKDG + S + T G+ +L++ DAG YSC+ N+ K T + Sbjct: 2151 ITWFKDGDPLVPSTEVVYTRGGR--QLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVY 2208 Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVE-----IPDETLDVTWYKKKSVIEDTEKFTLIS 1246 P+I T P +V A LT+E P T V+WY + + D L Sbjct: 2209 VPPTIEGTGEGPR--VVKAVAGRPLTLECVARGYPPPT--VSWYHEGLPVVDRNGTWL-- 2262 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKR--GS 1303 L + E Y+CV L V V+ P+++ E ++ G Sbjct: 2263 GAGGGVLSLESLGEASGGLYSCVASSPAGEAVLHYSVEVQVAPQLLVAEGLGQVTTLVGQ 2322 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 + L P P +W+ N ++ + S+ +L I VE AG++ + Sbjct: 2323 SLYLPCYASGSPVPTIQWLQNGHPAEELPGV--HVTSEGTTLHIDHVELGHAGLFACQAT 2380 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID 1423 N G A E+ +++ + PS ++ + +I + +P T+ Sbjct: 2381 NEAGTAAAEVELSVHELPS------VVIVGGENITAPFLQP-----VTLRCAGTGVPTPS 2429 Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 W + + S+Q K + Y +++ S +V+ I+ Sbjct: 2430 LRWWKDGVALAASGGSLQIEKVDLKDE-GTYTCVATNLAGESRKEVILRVLVPPNIEPGL 2488 Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXX 1540 V K + N + L C+ GVP P ++W++ + + A + + R Sbjct: 2489 VNKAVLE-----NASVTLECLASGVPPPDISWFKGRQPISAWDRAMVSTDGR-VLLIEQA 2542 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y+C+A N G E + + P IT+ + + +T G P Sbjct: 2543 QLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLP-PSLPGPVLLHSPVRLTCDAAGAP 2601 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P ++W K+GN + + V+ + + S S Y+ A + G +V L Sbjct: 2602 SPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGEDRRDVVL 2661 Query: 1661 KVYDKPSKPE 1670 +V+ + PE Sbjct: 2662 RVHSESRAPE 2671 Score = 77.8 bits (183), Expect = 3e-12 Identities = 59/221 (26%), Positives = 92/221 (41%), Gaps = 13/221 (5%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L+I V EGTYT VA N GE+ ++L++ PP + L + V + SV L Sbjct: 2446 LQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLV----PPNIEPGLVNKAVLENASVTL 2501 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 G P P I+W K +P+ A + +++ ++ D G Y A N G Sbjct: 2502 ECLASGVPPPDISWFKGRQPISAWDRAMVSTDGRVLLIEQAQLSDAGSYRCVASNVVGST 2561 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 E + V P P L V ++L P P + W ++ +S Sbjct: 2562 ELQYSLRVNVPPRITLPPSL------PGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVS 2615 Query: 875 PSETI-TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 + T Q F G + ++ + S DSG Y CVA ++ G+ Sbjct: 2616 TAGTAGLQVFPGGRVLMLASARVS--DSGSYSCVAVSAVGE 2654 Score = 69.3 bits (162), Expect = 1e-09 Identities = 68/338 (20%), Positives = 137/338 (40%), Gaps = 24/338 (7%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP-PGKPNI-LEIDSSS 1396 +S ++S I + + G Y+ + G + + + P PN+ + ++ Sbjct: 925 ESGNSSWEIPRASKAEEGTYECTAVSRAGTGRAKTQIVVTGPPPQLVPVPNVTVSPGETA 984 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 I C E N T +V +++ + + V + ++N + R++ A Sbjct: 985 ILSCLVLSEAPYNLT---WVRDWRVLSASTG-RVTQLADLSLEVRNTTPSDGGRYQCMAS 1040 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N ++ AS + +++E +P V ++ ++ + C G P P ++W Sbjct: 1041 NSNGVTRAS----VWLLVRE----APQVSIHTRSQRFSQGMEVRVRCSASGYPAPHISWS 1092 Query: 1517 RDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITI 1575 R+G+ L+ ++ + + Y C A N+ G E + + P ++ Sbjct: 1093 REGRALQEDSRVRVDAQGTLIIQGVAPEDAGSYSCQAANEIGRDEETVTLYYTDPPSVSA 1152 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS-VIRIKE 1634 N + G+E ++ G+PPP VIWY+ D E + ++ S ++RI Sbjct: 1153 VNGVVLAAK--GEEAVLECEATGVPPPRVIWYR------GDLEMILAPEDSISGMLRIPV 1204 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++ + YT A N G +S E+ L+V P E P Sbjct: 1205 VRERDAGVYTCRAVNELGDASAEIRLEVGHAPQLLELP 1242 Score = 67.7 bits (158), Expect = 3e-09 Identities = 112/543 (20%), Positives = 195/543 (35%), Gaps = 43/543 (7%) Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896 N E+ V E + + P P ITW+++ + + PS + G ++L Sbjct: 2124 NETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQLQLERAQGS 2183 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHLQKSYETEEGKTVILECQTSH- 954 D+G Y C ASN+ G R+ + V + + + G+ + LEC Sbjct: 2184 ---DAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAVAGRPLTLECVARGY 2240 Query: 955 -TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML--- 1010 + WYH + +D G+ C+ +L Sbjct: 2241 PPPTVSWYHEGLPV--VDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEAVLHYS 2298 Query: 1011 VVKETIPEFIRKL---QDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK 1067 V + P+ + Q + + + + S + W ++G P + Sbjct: 2299 VEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNGH---PAEELPGVHV 2355 Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVTVVELPPEIITRLQNQKVNKGNK 1123 L+I + + G ++C +E+ TA E++V ELP +I +N Sbjct: 2356 TSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHELPSVVIVGGENITAPFLQP 2415 Query: 1124 ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE--- 1179 T T +RW+KDG + L G L+I DL D G Y+C Sbjct: 2416 VTLRCAGTGVPTPSLRWWKDG--------VALAASGGS--LQIEKVDLKDEGTYTCVATN 2465 Query: 1180 -VGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE 1237 G S+ IL V P+I L + + T L +P D++W+K + I Sbjct: 2466 LAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECLASGVPPP--DISWFKGRQPIS 2523 Query: 1238 DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYER 1295 ++ + +D R L+I + D Y CV + +T+L+ + V PP+I + Sbjct: 2524 AWDRAMVSTD--GRVLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNVPPRITLPPSL 2581 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 + S V L D P P W+ + + + L + +D+ Sbjct: 2582 PGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDS 2641 Query: 1356 GIY 1358 G Y Sbjct: 2642 GSY 2644 Score = 67.3 bits (157), Expect = 4e-09 Identities = 63/272 (23%), Positives = 108/272 (39%), Gaps = 23/272 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP + V E + + LEC +P PDI+W FKG + + + ++ + +D Sbjct: 2480 VPPNIEPGLVNKAVLENASVTLECLASGVPPPDISW-FKGRQPISAWDRAM-VSTDGR-- 2535 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGE 750 VL I + G+Y VA N G L L++ PP++ + P V Sbjct: 2536 --VLLIEQAQLSDAGSYRCVASNVVGSTELQYSLRVNV----PPRITLPPSLPGPVLLHS 2589 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVYTLKAE 808 V L+ G P P + W K+ PV T + +L +V D G Y+ A Sbjct: 2590 PVRLTCDAAGAPSPMLMWLKDGNPVSTAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAV 2649 Query: 809 NSEGIAETSAVITVEEPT----------EENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 ++ G V+ V + E PP + Q ++V ++ L R Sbjct: 2650 SAVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHA 2709 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P P ++W ++ + P + + D +E+ Sbjct: 2710 VPPPVLSWRKDGRPLEPRPGVYLSADKALLEV 2741 Score = 62.9 bits (146), Expect = 9e-08 Identities = 66/274 (24%), Positives = 110/274 (40%), Gaps = 22/274 (8%) Query: 661 PEPDIAWLFKGEEIVP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719 P+P + W KG P + +A+ + ++ + +V G Y A N G A Sbjct: 1815 PKPQVTWR-KGPSSEPLRDRPGLAVLDEGSLF-----LASVSPSDGGDYECQATNEAGSA 1868 Query: 720 SLPIVLKIKTGEKEPPQVIEPLKSMIVR--QGESVILSAQVVGNPRPTITWCKNNKPVKA 777 S L + PP + E + V G+S+ L G P P ITW KN + + A Sbjct: 1869 SRRAKLVVHV----PPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPA 1924 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 + + D + D G+Y+ +AEN G A+ + V P L Sbjct: 1925 VGSHRLLDGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPS-----VLGAE 1979 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ-NFDGENIELVITNVD 896 QE+ +L R P P + W ++ + + E Q DG+ + + +++ Sbjct: 1980 AAQEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRITNSHLG 2039 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 D G Y+CVA + AG+ + ++ I E F Sbjct: 2040 ---DEGWYQCVAFSPAGQQTKDFQLRIHGEPSPF 2070 Score = 62.5 bits (145), Expect = 1e-07 Identities = 123/588 (20%), Positives = 217/588 (36%), Gaps = 62/588 (10%) Query: 633 PPTF--SKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 PPT S + V EG + C +P PDI W G+ +VP + Sbjct: 2117 PPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPLVPSTEVVYTRGGRQ-- 2174 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-----GEKEPPQVIEPLKSMI 745 L++ + GTY+ A N G L++ G E P+V++ + Sbjct: 2175 ----LQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAV---- 2226 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 G + L G P PT++W PV G + L+ G+Y+ Sbjct: 2227 --AGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGVLSLESLGEASGGLYSC 2284 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFI-NRFQEITVKEKGTIKLVARVTRNPVPSI 864 A + G A + E P L + ++T ++ L + +PVP+I Sbjct: 2285 VASSPAGEA------VLHYSVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTI 2338 Query: 865 TWYRNNEIISPSETIT-QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W +N P+E + + E L I +V+ +G + C A+N AG ++ A V + Sbjct: 2339 QWLQNGH---PAEELPGVHVTSEGTTLHIDHVELG-HAGLFACQATNEAGTAA--AEVEL 2392 Query: 924 DVEKVTFVKHLQKSYETEEG-KTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGR 980 V ++ V + T + V L C + T S +W+ + ++ I++ Sbjct: 2393 SVHELPSVVIVGGENITAPFLQPVTLRCAGTGVPTPSLRWWKDGVALAASGGSLQIEK-- 2450 Query: 981 XXXXXXXXXXXXDVGVIKCIVKD--QETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILE 1037 D G C+ + E+ ++++ +P I L + V E LE Sbjct: 2451 --------VDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLE 2502 Query: 1038 -VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 + D+ W + + I ++ G R L I + D G Y C+ + Sbjct: 2503 CLASGVPPPDISWFKGRQPIS-AWDRAMVSTDG--RVLLIEQAQLSDAGSYRCVASNVVG 2559 Query: 1097 TAEVTV---VELPPEI-ITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNH 1151 + E+ V +PP I + V + + + ++ W KDG+ + + Sbjct: 2560 STELQYSLRVNVPPRITLPPSLPGPVLLHSPVRLTCDAAGAPSPMLMWLKDGNPVSTAGT 2619 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPS 1195 L + + L + + D+G YSC VG + +L V S Sbjct: 2620 AGLQVFPGGRVLMLASARVSDSGSYSCVAVSAVGEDRRDVVLRVHSES 2667 Score = 61.7 bits (143), Expect = 2e-07 Identities = 99/499 (19%), Positives = 181/499 (36%), Gaps = 39/499 (7%) Query: 1279 LKVEVVEFPPKI--VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 L+ ++V PP I + E + G V L + + P P+ W + + T+ Sbjct: 2109 LQRKLVTAPPTIWGSNETSEVAVMEGHPVWFLCEARGVPTPDITWFKDGDPL--VPSTEV 2166 Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNILEID 1393 L +++ + +DAG Y + N G + + + P+ G P +++ Sbjct: 2167 VYTRGGRQLQLERAQGSDAGTYSCKASNAVGVVEKTTRLEVYVPPTIEGTGEGPRVVKAV 2226 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTT-EWISVKNITKTQTSIQNLKTNSSYRFR 1452 + T+ +Y +D W+ S+++L S + Sbjct: 2227 AGRPLTLECVARGYPPPTVSWYHEGLPVVDRNGTWLGAGGGV---LSLESLGEASGGLYS 2283 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A S A E +Y V + Q V + L +TT + + L C G P P Sbjct: 2284 CVAS-----SPAGEAVLHYSVEVQVAPQL-LVAEGLGQVTTLVGQSLYLPCYASGSPVPT 2337 Query: 1513 VTWYRDG---KKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ 1569 + W ++G ++L T E + C A N+ G + + + Sbjct: 2338 IQWLQNGHPAEELPGVHVTSEG-TTLHIDHVELGHAGLFACQATNEAGTAAAEVELSVHE 2396 Query: 1570 KP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 P V+ + E+I + G+P P + W+K+G + Sbjct: 2397 LPSVVIVGGENITAPFL--QPVTLRCAGTGVPTPSLRWWKDG----------VALAASGG 2444 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWK 1688 ++I+++ YT A+N AG S EV L+V P+ G V + SVT+E Sbjct: 2445 SLQIEKVDLKDEGTYTCVATNLAGESRKEVILRVLVPPNIEPGLVNKAVLENASVTLECL 2504 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 G+ + K + W + A V D I++ + +R +A N VG Sbjct: 2505 A----SGVPPPDISWFKGRQPISAWDR-AMVSTDGRVLLIEQAQLSDAGSYRCVASNVVG 2559 Query: 1749 FSEALESEPIVIKTALDVP 1767 +E S + + + +P Sbjct: 2560 STELQYSLRVNVPPRITLP 2578 Score = 54.0 bits (124), Expect = 4e-05 Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 517 RPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576 R + G V+ C GYP P I+W R+ ++ ++ D TL+I+ V PE Sbjct: 1065 RSQRFSQGMEVRVRCSASGYPAPHISWSREGRALQEDSRVRV----DAQGTLIIQGVAPE 1120 Query: 577 DAGTFTCVAKNAAGFASSTTELIVEAPLS 605 DAG+++C A N G T L P S Sbjct: 1121 DAGSYSCQAANEIGRDEETVTLYYTDPPS 1149 Score = 53.2 bits (122), Expect = 8e-05 Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G V F C+ G P P ITWF+ + PS ++ Y L + DAGT++ Sbjct: 2133 EGHPVWFLCEARGVPTPDITWFKDGDPLVPST--EVVYTRGG-RQLQLERAQGSDAGTYS 2189 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGS 609 C A NA G TT L V P + G+ Sbjct: 2190 CKASNAVGVVEKTTRLEVYVPPTIEGT 2216 Score = 52.8 bits (121), Expect = 1e-04 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 6/169 (3%) Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKVEVVE 1285 VTW K S E ++ + + +L + + D +Y C +A S ++ VV Sbjct: 1819 VTWRKGPSS-EPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASRRAKLVVH 1877 Query: 1286 FPPKIVDYEREYRIK--RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 PP + + R + G +TL D FP P W+ N + I + +D A Sbjct: 1878 VPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHR-LLDGARA 1936 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI 1392 L +++ D+G+Y R EN G A + ++ +L PS G E+ Sbjct: 1937 -LHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEV 1984 Score = 51.6 bits (118), Expect = 2e-04 Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGT 580 T +G C G P P ITW ++T + S+D +Y+ TLVI +DAG Sbjct: 1433 TNEGVPASLPCVASGVPTPTITWTKETNALA-SRD--PHYNVSKDGTLVIPRPSVQDAGA 1489 Query: 581 FTCVAKNAAGFASSTTELIV 600 + C A NA GF+S L V Sbjct: 1490 YVCTATNAVGFSSQEMRLSV 1509 Score = 51.2 bits (117), Expect = 3e-04 Identities = 53/241 (21%), Positives = 100/241 (41%), Gaps = 18/241 (7%) Query: 860 PVPSITWYR--NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P P +TW + ++E + + +G L + +V S D GDY+C A+N AG +S Sbjct: 1815 PKPQVTWRKGPSSEPLRDRPGLAVLDEGS---LFLASV-SPSDGGDYECQATNEAGSASR 1870 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNKKEISGMDHREI 975 A++ + V + + G+++ LEC + + + W N ++I + + Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRL 1930 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKD 1032 + R D G+ C ++Q + + P + EV Sbjct: 1931 LDGAR--ALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLA 1988 Query: 1033 VAILEVE---INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 A E+E + T V W +DG+ + + + ++ G + L I N+ + DEG Y C Sbjct: 1989 GAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQV--LRITNSHLGDEGWYQC 2046 Query: 1090 I 1090 + Sbjct: 2047 V 2047 Score = 49.6 bits (113), Expect = 0.001 Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 23/198 (11%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY-VDEGSDILLECR 656 LI +A LSD GS V + + +PP + P V S + L C Sbjct: 2538 LIEQAQLSDAGSYRCVASNVVGSTELQYS-LRVNVPPRITLPPSLPGPVLLHSPVRLTCD 2596 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS--VLKITNVKKFQEGTYTVVAVN 714 P P + WL G + S A + + ++ VL + + + G+Y+ VAV+ Sbjct: 2597 AAGAPSPMLMWLKDGNPV------STAGTAGLQVFPGGRVLMLASARVSDSGSYSCVAVS 2650 Query: 715 REGEASLPIVLKIKT-------------GEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 GE +VL++ + + PP ++ +++ V ESV L + Sbjct: 2651 AVGEDRRDVVLRVHSESRAPEAAGCGLEAQDAPPSILGEEQNVSVVANESVALECRSHAV 2710 Query: 762 PRPTITWCKNNKPVKALP 779 P P ++W K+ +P++ P Sbjct: 2711 PPPVLSWRKDGRPLEPRP 2728 Score = 49.2 bits (112), Expect = 0.001 Identities = 51/206 (24%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 749 GESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 G+S+ G P+P +TW K +++P++ P + D S+ L D G Y + Sbjct: 1802 GKSLERDEGWAGTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSL-FLASVSPSDGGDYECQ 1860 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N G A A + V P + R ++ ++ L P P ITW Sbjct: 1861 ATNEAGSASRRAKLVVHVPPSLRED-----GRRANVSGMAGQSLTLECDANGFPAPEITW 1915 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +N I P+ + DG L + E DSG Y C A N AG + + + + Sbjct: 1916 LKNGRQI-PAVGSHRLLDGAR-ALHFPRI-QEGDSGLYSCRAENQAGTAQRDFDLLVLIP 1972 Query: 927 KVTFVKHLQKSYETEEGKTVILECQT 952 + G LEC+T Sbjct: 1973 PSVLGAEAAQEVVGLAGAGAELECRT 1998 Score = 48.0 bits (109), Expect = 0.003 Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 21/195 (10%) Query: 626 ADILEGIPPTFSKKPKAQYVD--EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 A ++ +PP+ + + V G + LEC P P+I WL G +I P Sbjct: 1872 AKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQI-PAVGSHRL 1930 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPL 741 ++ L +++ G Y+ A N+ G A L + PP V+ E Sbjct: 1931 LDG-----ARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLI----PPSVLGAEAA 1981 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKV 797 + ++ G L + +G P P + W K+ +PV + + DG IT + Sbjct: 1982 QEVVGLAGAGAELECRTLGVPTPQVEWTKDGQPVFLGEPRVQLQEDGQVLRIT---NSHL 2038 Query: 798 KDEGVYTLKAENSEG 812 DEG Y A + G Sbjct: 2039 GDEGWYQCVAFSPAG 2053 Score = 47.6 bits (108), Expect = 0.004 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ EC G+P P+ITW + I ++ D L + D+G ++C Sbjct: 1896 GQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLL---DGARALHFPRIQEGDSGLYSC 1952 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSE 610 A+N AG A +L+V P S G+E Sbjct: 1953 RAENQAGTAQRDFDLLVLIPPSVLGAE 1979 Score = 47.2 bits (107), Expect = 0.005 Identities = 33/166 (19%), Positives = 58/166 (34%), Gaps = 5/166 (3%) Query: 1505 FGGVPQPKVTWYR--DGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 + G P+P+VTW + + L+ + Y+C A N+ G Sbjct: 1811 WAGTPKPQVTWRKGPSSEPLRDRPGLAVLDEGSLFLASVSPSDGGDYECQATNEAGSASR 1870 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 + + P + G + G P PE+ W KNG ++ + + Sbjct: 1871 RAKLVVHVPPSLREDGRRANVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRL 1930 Query: 1622 TTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + + ++ S Y+ A N AGT+ + L V PS Sbjct: 1931 L--DGARALHFPRIQEGDSGLYSCRAENQAGTAQRDFDLLVLIPPS 1974 Score = 46.4 bits (105), Expect = 0.009 Identities = 37/186 (19%), Positives = 71/186 (38%), Gaps = 4/186 (2%) Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT--AKATYENRXXXXXXXXXXXXXXX 1547 N++ + + L C G P P++TW ++G+++ + + Sbjct: 1890 NVSGMAGQSLTLECDANGFPAPEITWLKNGRQIPAVGSHRLLDGARALHFPRIQEGDSGL 1949 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWY 1607 Y C A N G + + + P + + + G + G+P P+V W Sbjct: 1950 YSCRAENQAGTAQRDFDLLVLIPPSVLGAEAAQEVVGLAGAGAELECRTLGVPTPQVEWT 2009 Query: 1608 KNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 K+G + E + +E V+RI Y A + AG + + L+++ +PS Sbjct: 2010 KDGQPVFLG-EPRVQLQEDGQVLRITNSHLGDEGWYQCVAFSPAGQQTKDFQLRIHGEPS 2068 Query: 1668 K-PEGP 1672 P P Sbjct: 2069 PFPSSP 2074 Score = 45.2 bits (102), Expect = 0.020 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 + ++V EC G P P I+WF+ I + D M D V L+I + DAG++ Sbjct: 2495 ENASVTLECLASGVPPPDISWFKGRQPIS-AWDRAMVSTDGRV--LLIEQAQLSDAGSYR 2551 Query: 583 CVAKNAAGFASSTTELIVEAP 603 CVA N G L V P Sbjct: 2552 CVASNVVGSTELQYSLRVNVP 2572 Score = 44.0 bits (99), Expect = 0.046 Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 2/71 (2%) Query: 535 GYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 G P+PQ+TW R+ +P +D D +L + V P D G + C A N AG AS Sbjct: 1813 GTPKPQVTW-RKGPSSEPLRDRPGLAVLDE-GSLFLASVSPSDGGDYECQATNEAGSASR 1870 Query: 595 TTELIVEAPLS 605 +L+V P S Sbjct: 1871 RAKLVVHVPPS 1881 Score = 40.3 bits (90), Expect = 0.57 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 3/80 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V +C+ +G P P +TW + + + P D +L + + D+G + C Sbjct: 1534 GDEVTLDCEAQGSPPPLVTWTKDSRHMLPITDRHHLLPP---GSLHLAQAQVSDSGLYEC 1590 Query: 584 VAKNAAGFASSTTELIVEAP 603 A N AG A+ L V+ P Sbjct: 1591 TASNPAGSATQYYILRVQVP 1610 Score = 39.5 bits (88), Expect = 0.99 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 5/78 (6%) Query: 527 VQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 V C V G PRP+ W + + P + D +L + + EDAG ++CV Sbjct: 1348 VSLPCIVLAGRPRPERRWLKAGMPLPPGSRHSIRAD----GSLHLDQALLEDAGRYSCVV 1403 Query: 586 KNAAGFASSTTELIVEAP 603 N AG +L+V+ P Sbjct: 1404 SNTAGSHHRDVQLVVQVP 1421 Score = 39.5 bits (88), Expect = 0.99 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 5/100 (5%) Query: 503 SEEQSMAP--IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 S E +AP + E L T G ++ C G P P I W + P+++ + Sbjct: 2298 SVEVQVAPQLLVAEGLGQVTTLVGQSLYLPCYASGSPVPTIQWLQNG---HPAEELPGVH 2354 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 TL I V AG F C A N AG A++ EL V Sbjct: 2355 VTSEGTTLHIDHVELGHAGLFACQATNEAGTAAAEVELSV 2394 Score = 38.3 bits (85), Expect = 2.3 Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 7/99 (7%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR---QTAIIKPSQDFQMYYD 561 E AP +E + G + C+ G+P P ITW R Q ++P + + Sbjct: 1231 EVGHAPQLLELPQDVTVELGRSALLACRATGHPLPTITWHRGDDQPLGLRPGS--RTGWP 1288 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 D V L V PED + C A+N G + L+V Sbjct: 1289 DSGV--LFFESVVPEDQALYVCEAENVFGKVQAEAYLLV 1325 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 9/103 (8%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 EK +L V+ PT E P V+ + G + EC GYP P ++W+ + Sbjct: 2200 EKTTRLEVYVPPTIEGTGEGPRVVKAVA------GRPLTLECVARGYPPPTVSWYHEGL- 2252 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 P D + L + + G ++CVA + AG A Sbjct: 2253 --PVVDRNGTWLGAGGGVLSLESLGEASGGLYSCVASSPAGEA 2293 Score = 37.5 bits (83), Expect = 4.0 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 10/79 (12%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY-DDDNVATLV-IREVFPEDAGTF 581 G EC+ G P P++ W+R D +M +D+++ ++ I V DAG + Sbjct: 1162 GEEAVLECEATGVPPPRVIWYR--------GDLEMILAPEDSISGMLRIPVVRERDAGVY 1213 Query: 582 TCVAKNAAGFASSTTELIV 600 TC A N G AS+ L V Sbjct: 1214 TCRAVNELGDASAEIRLEV 1232 >UniRef50_A7RT26 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 457 Score = 110 bits (264), Expect = 5e-22 Identities = 92/396 (23%), Positives = 165/396 (41%), Gaps = 24/396 (6%) Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 ++L + + + P FV + K +G +V FEC +G P P +TW + + + Sbjct: 71 NELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALNT 130 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE----LIVEAPLSDHG 608 S D + Y N L+I V D+G + C A + G + E +I +D Sbjct: 131 SVDPRFY---SNGTHLMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEA 187 Query: 609 SEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAW 667 S ++ PP F + K + ++E ++ L C+L P + W Sbjct: 188 SYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVW 247 Query: 668 LFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 L E+ PD + + S + S L I NV + E Y +A N + + Sbjct: 248 LKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 307 Query: 728 KTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK------ 781 + PP+ + K+ V + +V L+ Q+ P+ ++TW K+N P+ P + Sbjct: 308 VV--QYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHP 365 Query: 782 -SDGDTHSITILKPKKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRF 839 S G+T S + DE Y+ KA N+ G + ++TV P + L I + Sbjct: 366 GSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKF-----LEILKA 420 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 +E+ E + L ++ P+ ++ W ++N + P Sbjct: 421 EEMR-NETDNLTLTCKLEGKPLATVLWLKDNTELEP 455 Score = 88.6 bits (210), Expect = 2e-15 Identities = 84/347 (24%), Positives = 139/347 (40%), Gaps = 47/347 (13%) Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 +PK + EG + EC+ P P++ WL G ++ +++ + ++L IT Sbjct: 2 EPKGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSA------VNTSVDPRFYSNDTILMIT 55 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 NV + GTY+ A N G S L ++ G P+ + + +G SV Sbjct: 56 NVSRIDSGTYSCNASNELGIISAEAALDVRYG----PEFVNVPQDKTPNEGWSVTFECHT 111 Query: 759 VGNPRPTITWCKNNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAEN-----SE 811 GNP PT+TW KN + P TH + I + D G Y A + ++ Sbjct: 112 KGNPPPTVTWLKNGSALNTSVDPRFYSNGTH-LMITNVNRT-DSGAYRCNASSILGPEND 169 Query: 812 GIAETSAVITVEEPTEE--------NAE--------------PPLFINRFQ-EITVKEKG 848 G + +I+ T+E NA PP F+ + E T+ E Sbjct: 170 GNETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNETD 229 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSE--TITQ--NFDGENIELVITNVDSEIDSGDY 904 + L ++ P+ ++ W ++N + P ITQ + D L I NV D Y Sbjct: 230 NLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH-DEAYY 288 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 KC+A+N+ ++ ++ V+ K+ E V L CQ Sbjct: 289 KCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQ 335 Score = 76.6 bits (180), Expect = 7e-12 Identities = 89/362 (24%), Positives = 147/362 (40%), Gaps = 58/362 (16%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F P+ + +EG + EC P P + WL G ++ +++ + + Sbjct: 88 PEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSA------LNTSVDPRFYSNGT 141 Query: 694 VLKITNVKKFQEGTYTVVA--------------------VNREGEASLPIVLKIKTGEKE 733 L ITNV + G Y A +NR EAS K GEK Sbjct: 142 HLMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKT 201 Query: 734 ----------PPQVIEPLKSM-IVRQGESVILSAQVVGNPRPTITWCKNN---KPVKAL- 778 PP+ ++ LK + + +++ L+ ++ G P T+ W K+N +P L Sbjct: 202 SGSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLI 261 Query: 779 ---PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 P+ D ++TI+ + DE Y A N+ +T+ T + PP F Sbjct: 262 ITQPSSVDSGESTLTIINVHR-HDEAYYKCLANNT---VDTTTSTTNTSVVVQY--PPKF 315 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE---TITQ--NFDGENIEL 890 + TV EK + L ++ P S+TW ++N + S T+T ++ L Sbjct: 316 FQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSL 375 Query: 891 VITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILE 949 ITN+ D Y C A N+AG KSS +T++ F++ L+ E + L Sbjct: 376 TITNL-VRTDEARYSCKAINAAGEKSSEQGLLTVNYPP-KFLEILKAEEMRNETDNLTLT 433 Query: 950 CQ 951 C+ Sbjct: 434 CK 435 Score = 59.7 bits (138), Expect = 9e-07 Identities = 30/82 (36%), Positives = 44/82 (53%), Gaps = 3/82 (3%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 K T +G V+FECQ G P P +TW + + + S D +Y +D + L+I V D+ Sbjct: 6 KTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVD-PRFYSNDTI--LMITNVSRIDS 62 Query: 579 GTFTCVAKNAAGFASSTTELIV 600 GT++C A N G S+ L V Sbjct: 63 GTYSCNASNELGIISAEAALDV 84 Score = 58.8 bits (136), Expect = 2e-06 Identities = 91/373 (24%), Positives = 147/373 (39%), Gaps = 61/373 (16%) Query: 1074 LYIRNTSVHDEGEYSCILRDES--CTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIEL 1130 L I N S D G YSC +E +AE + V PE + Q++ N+G TFE Sbjct: 52 LMITNVSRIDSGTYSCNASNELGIISAEAALDVRYGPEFVNVPQDKTPNEGWSVTFECH- 110 Query: 1131 TKGDA--LVRWFKDGSEIQ-------FSN--HIQLTI---------------------DG 1158 TKG+ V W K+GS + +SN H+ +T DG Sbjct: 111 TKGNPPPTVTWLKNGSALNTSVDPRFYSNGTHLMITNVNRTDSGAYRCNASSILGPENDG 170 Query: 1159 KKQK-LKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPANT 1212 + L I + + D Y+C N+ + L V P F L + + Sbjct: 171 NETSFLMISNLNRTDEASYTCRAKNAAGEKTSGSVNLAVNYPP-KFLQSLKDEETLNETD 229 Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLIS----DVKKRTLIIRKCTEDDQCEYT 1267 + LT ++ + L V W K + +E + + D + TL I D+ Y Sbjct: 230 NLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYK 289 Query: 1268 CVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 C+ +D ++T VV++PPK + + S+VTL + P+ + W+ + Sbjct: 290 CLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNVTLTCQLECKPKCSVTWLKD 349 Query: 1325 SKII----KKCKHTKP-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 + + + T P S + ++SLTI + TD Y + N G E + ++ Sbjct: 350 NTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEKSSEQGLLTVN 409 Query: 1380 KPSPPGKPNILEI 1392 P P LEI Sbjct: 410 YP-----PKFLEI 417 Score = 58.4 bits (135), Expect = 2e-06 Identities = 41/168 (24%), Positives = 64/168 (38%), Gaps = 10/168 (5%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXX 1546 K TT + ++ C G P P VTW + G + T+ Y N Sbjct: 4 KGKTTTEGQVVKFECQTTGNPSPNVTWLKSGSAVNTSVDPRFYSNDTILMITNVSRIDSG 63 Query: 1547 XYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT--AVIEGIPPPEV 1604 Y C A N+ G + + ++ P ++ Q + W VT +G PPP V Sbjct: 64 TYSCNASNELGIISAEAALDVRYGPEFV----NVPQDKTPNEGWSVTFECHTKGNPPPTV 119 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 W KNG+ L + + + + I + R+ S Y AS+ G Sbjct: 120 TWLKNGSALNTSVDPRFYS--NGTHLMITNVNRTDSGAYRCNASSILG 165 Score = 49.6 bits (113), Expect = 0.001 Identities = 95/438 (21%), Positives = 155/438 (35%), Gaps = 55/438 (12%) Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 +VTW K S + + S+ L+I + D Y+C + + + V Sbjct: 27 NVTWLKSGSAVNTSVDPRFYSN--DTILMITNVSRIDSGTYSCNASNELGIISAEAALDV 84 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 + P+ V+ ++ G VT + P P W+ N + P S Sbjct: 85 RYGPEFVNVPQDKTPNEGWSVTFECHTKGNPPPTVTWLKNGSALN--TSVDPRFYSNGTH 142 Query: 1345 LTIKKVENTDAGIYK------LRLENNCGHADVEM--NVTILDKPSPP--GKPNILEIDS 1394 L I V TD+G Y+ L EN+ M N+ D+ S K E S Sbjct: 143 LMITNVNRTDSGAYRCNASSILGPENDGNETSFLMISNLNRTDEASYTCRAKNAAGEKTS 202 Query: 1395 SSINICWDEP---------ENTGNST---IIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 S+N+ + P E T N T + +E + + T W+ K+ T+ + + Sbjct: 203 GSVNLAVNYPPKFLQSLKDEETLNETDNLTLTCKLEGKPLATVVWL--KDNTELEPDSRL 260 Query: 1443 LKTN-SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--------VEKP------ 1487 + T SS + +++ E YYK + + + T V+ P Sbjct: 261 IITQPSSVDSGESTLTIINVHRHDEA--YYKCLANNTVDTTTSTTNTSVVVQYPPKFFQS 318 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--------KATYENRXXX-XXX 1538 KN T ++ LTC P+ VTW +D L T+ +Y N Sbjct: 319 PKNETVTEKSNVTLTCQLECKPKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTIT 378 Query: 1539 XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y C A N GE + + P + ++ D +T +EG Sbjct: 379 NLVRTDEARYSCKAINAAGEKSSEQGLLTVNYPPKFLEILKAEEMRNETDNLTLTCKLEG 438 Query: 1599 IPPPEVIWYKNGNKLEND 1616 P V+W K+ +LE D Sbjct: 439 KPLATVLWLKDNTELEPD 456 Score = 47.2 bits (107), Expect = 0.005 Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 21/194 (10%) Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-------TAKATYEN-RXXXXXXXXXXX 1543 T +++ LTC G P V W +D +L+ T ++ ++ Sbjct: 224 TLNETDNLTLTCKLEGKPLATVVWLKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRH 283 Query: 1544 XXXXYKCIAFN--DHGEVETSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGI 1599 YKC+A N D T+ V +Q P S NE + +K V +T +E Sbjct: 284 DEAYYKCLANNTVDTTTSTTNTSVVVQYPPKFFQSPKNETVTEKSNV----TLTCQLECK 339 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTK-----EKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 P V W K+ L+ + T TS + I L R+ ++Y+ +A N AG Sbjct: 340 PKCSVTWLKDNTPLDTSPDRITVTHPGSYGNTTSSLTITNLVRTDEARYSCKAINAAGEK 399 Query: 1655 SVEVTLKVYDKPSK 1668 S E L + P K Sbjct: 400 SSEQGLLTVNYPPK 413 Score = 39.5 bits (88), Expect = 0.99 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 7/127 (5%) Query: 1548 YKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIW 1606 Y C A N GE + V + + P S +D + ++ D +T +EG P V+W Sbjct: 189 YTCRAKNAAGEKTSGSVNLAVNYPPKFLQSLKDEETLNET-DNLTLTCKLEGKPLATVVW 247 Query: 1607 YKNGNKLENDKEYNITTKEKT----SVIRIKELKRSHSSKYTIEASNTAG-TSSVEVTLK 1661 K+ +LE D IT S + I + R + Y A+NT T+S T Sbjct: 248 LKDNTELEPDSRLIITQPSSVDSGESTLTIINVHRHDEAYYKCLANNTVDTTTSTTNTSV 307 Query: 1662 VYDKPSK 1668 V P K Sbjct: 308 VVQYPPK 314 >UniRef50_Q62234 Cluster: Myomesin-1; n=32; cellular organisms|Rep: Myomesin-1 - Mus musculus (Mouse) Length = 1666 Score = 109 bits (263), Expect = 6e-22 Identities = 106/461 (22%), Positives = 189/461 (40%), Gaps = 23/461 (4%) Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKP 1669 EN + N K+ + +L S ++ + SN+AG + + EVT+ V DK P Sbjct: 660 ENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTV-VGDKLDIP 718 Query: 1670 EGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 + P +I + SV + W+ D EL Y IE + +W + + Sbjct: 719 KAPGKIIPSRNTDTSVVVSWEESRD--AKELVGYYIEASVVGSGKWEPCNNNPVKGSRFT 776 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 L Y+FRV A N G SE + +SE I +K A+ + + + Sbjct: 777 CHGLTTAQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAI---GGGVSPDVWPQLSDTPGGL 833 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 T NG SP K + + + +++ + Q + + + Sbjct: 834 TDSRGGMNGASPPTSQKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEA 893 Query: 1847 TSLPYTSDDKITIGKT--LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF 1904 S + K + PS P + ES S+ L W +P++ GG+ IT Y + + Sbjct: 894 APEEEQSQSEPPKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNY 953 Query: 1905 KTVKGK---SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP-TESQSVRLE 1960 + V G+ W + S + I N+KE F++SA N G+ P T S+ + E Sbjct: 954 REVVGEVPGKWREANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCE 1013 Query: 1961 KHA-TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT--KTMWMEVG 2017 + VP PP + +++ V N ++ W P + G P+ GY + +++ + W + Sbjct: 1014 EWTIAVPGPPHS-VKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLN 1072 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 + + ++ L E Y+ R+ A N+ G+ +P + P Sbjct: 1073 EAAIVNKYLRVQGLKEGTCYVFRVRAVNQAGVGKPSDLAGP 1113 Score = 88.2 bits (209), Expect = 2e-15 Identities = 101/407 (24%), Positives = 160/407 (39%), Gaps = 29/407 (7%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727 P + + E +R V + WKPP G E Y +EK + W +V ++ + Sbjct: 619 PPTDLSVTEATRSYVVLSWKPP-GQRGHEGIMYFVEKCDVGAENWQRVNTELPVKSPRFA 677 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L E Y FRV N G E E +E V+ LD+P D SV + Sbjct: 678 LFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDT-SVVV 736 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINT--TYQFRIYARN 1843 +W E ++ Y +E G KW+ +R + T +Y FR+ A N Sbjct: 737 SW--EESRDAKELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVN 794 Query: 1844 EIGTSLPYTSDD-----KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT 1898 G S Y+ D K IG ++P P+ +S++ L + NG SP T Sbjct: 795 AAGLS-EYSQDSEAIEVKAAIGGGVSPDVWPQ---LSDTPG---GLTDSRGGMNGASPPT 847 Query: 1899 NYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 + + + G + K E + + +S+ +SQS Sbjct: 848 S---QKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEAAPEEEQSQSEP 904 Query: 1959 LEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM---W 2013 +K + P+AP +I + S + ++ W P+ GGA + GY + R+V + W Sbjct: 905 PKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKW 964 Query: 2014 MEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 E V+ + I +L EN Y ++ A N GL P E FK Sbjct: 965 REANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFK 1011 Score = 66.5 bits (155), Expect = 8e-09 Identities = 57/239 (23%), Positives = 97/239 (40%), Gaps = 33/239 (13%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P+ P + V ++ + + W +P +GGSPI Y I+ V +W++ Sbjct: 489 PAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARF 548 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE----------SQSVRLEKH------------- 1962 + + E IFR+ A N G+ LP+ ++ RL+ H Sbjct: 549 PVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHPSAPWTGQIIVTE 608 Query: 1963 -----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 +P PPT L + + V+ SW P G ++ Y + DV W V Sbjct: 609 EEPTEGVIPGPPT-DLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCDVGAENWQRVN 666 Query: 2018 -KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEGSHADEEPGE 2075 ++ V + +F + DL E +Y R+ N G+ EP E+ E + G+ + PG+ Sbjct: 667 TELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTE--VTVVGDKLDIPKAPGK 723 Score = 64.5 bits (150), Expect = 3e-08 Identities = 51/198 (25%), Positives = 82/198 (41%), Gaps = 6/198 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHE 1924 P P + V+E+T V L W P G I Y +E V ++W ++ T + Sbjct: 617 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCDVGAENWQRVNTELPVKSPR 675 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIV 1983 + ++ E FR+ N+ GV P+E+ V + +P P + R +++V Sbjct: 676 FALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTSVV 735 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 + SW E L+GY I V W V +F L+ +Y+ R+ A Sbjct: 736 V-SW--EESRDAKELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRA 792 Query: 2044 RNEIGLSEPLESDEPFKV 2061 N GLSE + E +V Sbjct: 793 VNAAGLSEYSQDSEAIEV 810 Score = 63.7 bits (148), Expect = 5e-08 Identities = 34/114 (29%), Positives = 54/114 (47%), Gaps = 3/114 (2%) Query: 1963 ATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 A + P APL++ + +N ++ SW P DGG+P+LGY I +V W + Sbjct: 483 AEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTP 542 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVI-PGEGSHADEEP 2073 V +F + L E +Y+ R+ A N+ G+ P EP + P E + P Sbjct: 543 VKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHP 596 Score = 58.8 bits (136), Expect = 2e-06 Identities = 42/164 (25%), Positives = 65/164 (39%), Gaps = 7/164 (4%) Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 PEV WY+NG + K + + L + YTI + Sbjct: 418 PEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 477 Query: 1662 VYDKPSKPEGP------VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIK 1715 V D ++ EG V+ + +++ + I WK P DGG + Y I+K E + W + Sbjct: 478 VRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQ 537 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPI 1758 D + + L E Y+FRV A N G + SEP+ Sbjct: 538 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPV 581 Score = 57.6 bits (133), Expect = 4e-06 Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 13/201 (6%) Query: 1280 KVEVVEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS 1337 KVE+ F K V + RE + G V + + + F QP +W N + K +P Sbjct: 381 KVEI-HFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEVQWYRNGAPVSPSKWVQPH 438 Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD-----KPSPPGKPNILEI 1392 A+LT + D G+Y +R+ + V + D + +P +++ + Sbjct: 439 WSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSL 498 Query: 1393 DSSS--INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSS 1448 D++ I I W +P G S I+ Y ++ E+ T W + + + + L S Sbjct: 499 DANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGRS 558 Query: 1449 YRFRAYAVNEVDISDASETTE 1469 Y FR AVN+ I S +E Sbjct: 559 YIFRVRAVNKTGIGLPSRVSE 579 Score = 54.4 bits (125), Expect = 3e-05 Identities = 49/232 (21%), Positives = 90/232 (38%), Gaps = 13/232 (5%) Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 L + +++ + +E+ + AP F+ K R + V+ C V G+P P++TW++ Sbjct: 234 LKKTLEETQTYHGKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKN 293 Query: 547 TAIIKPSQDFQMYYDDD--NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 I + Y + + TL I + ED + A N G S+ ++V+ Sbjct: 294 QVPINVHANPGKYIIESRYGMHTLEISKCDFEDTAQYRASAMNVQGELSAYASVVVKRYK 353 Query: 605 SD-HGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPE- 662 + S + + F K + EG + L CR+V PE Sbjct: 354 GELDESLLRGGVSMPLSFAVTPYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEI 413 Query: 663 ----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 P++ W G + P + + D + L +++ K EG YT+ Sbjct: 414 KHFQPEVQWYRNGAPVSPSKWVQPHWSGDR----ATLTFSHLNKEDEGLYTI 461 Score = 49.2 bits (112), Expect = 0.001 Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 5/97 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEW--ISVKNITK 1435 PS P LE S+ + W +P+ TG + I Y V Y+E+ +W ++K ++ Sbjct: 915 PSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKWREANIKAVSD 974 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 I NLK N+ Y+F+ A+N + S +E +K Sbjct: 975 AAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFK 1011 Score = 48.8 bits (111), Expect = 0.002 Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 9/141 (6%) Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGP---VIMREISRESVT 1684 +I LK + ++ + A N AG S+V K + GP V + E+ + S+ Sbjct: 978 KISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCEEWTIAVPGPPHSVKLSEVRKNSLV 1037 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPD--NNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 ++WKPP+ G +T Y ++ E +++W + + + +Q L E Y+FRV Sbjct: 1038 LQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNKYLRVQGLKEGTCYVFRVR 1097 Query: 1743 AQNPVGFSEALE-SEPIVIKT 1762 A N G + + + P+V +T Sbjct: 1098 AVNQAGVGKPSDLAGPVVAET 1118 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP ++ E S + + W P G+ I+Y+ VE ++ W V + + Sbjct: 617 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYF-VEKCDVGAENWQRVNTELPVKSPR 675 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI-QSPTVEKPLKNITT 1493 ++ +L SYRFR N + + SETTE V + I ++P P +N T Sbjct: 676 FALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDT 732 Score = 47.2 bits (107), Expect = 0.005 Identities = 68/332 (20%), Positives = 128/332 (38%), Gaps = 25/332 (7%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDN 564 + P F E L + T + V +C+V + I W++ I + D Sbjct: 1335 RKQGPHFAEYLSWEVTGE-CNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF---KDG 1390 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA---PLSDHGSEMTVXXXXXXXX 621 + TL+I E +DAG + + K+ G S +L+ EA +++ ++ + Sbjct: 1391 ICTLLITEFSKKDAGFYEVILKDDRGKDKSRLKLVDEAFQDLMTEVCKKIALSATDLKIQ 1450 Query: 622 XXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS 681 L + K + G+ I R+ + + WL E P N Sbjct: 1451 STAEGIRLYSFVCYYLDDLKVNWSHNGTGIKYTDRVKSGVTGEQIWLQINE---PTPN-- 1505 Query: 682 VAIESDMHMYCSVLKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEP 740 D Y V+++ + K + T + E A + + EK +V+ Sbjct: 1506 -----DKGKY--VMELFDGKTGHQKTVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGG 1558 Query: 741 LKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796 L ++ +++G+++ L+ V G+P P ++W KN KP+ + K + + + Sbjct: 1559 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVS 1618 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 D G Y L +N G + ++V P EE Sbjct: 1619 TADSGKYGLVVKNKYGSETSDFTVSVFIPEEE 1650 Score = 46.8 bits (106), Expect = 0.007 Identities = 57/206 (27%), Positives = 85/206 (41%), Gaps = 38/206 (18%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK--ALPTK----SDGDTH 787 P +I+P +S V + E+V L V G P P +TW KN P+ A P K S H Sbjct: 257 PEFIIKP-RSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH 315 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEP--------PL----- 834 ++ I K +D Y A N +G A + V+ E E PL Sbjct: 316 TLEISKCD-FEDTAQYRASAMNVQGELSAYASVVVKRYKGELDESLLRGGVSMPLSFAVT 374 Query: 835 -----------FINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSET 878 F ++F +E T+ L RV P P + WYRN +SPS+ Sbjct: 375 PYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGAPVSPSKW 434 Query: 879 ITQNFDGENIELVITNVDSEIDSGDY 904 + ++ G+ L ++++ E D G Y Sbjct: 435 VQPHWSGDRATLTFSHLNKE-DEGLY 459 Score = 45.2 bits (102), Expect = 0.020 Identities = 60/231 (25%), Positives = 92/231 (39%), Gaps = 39/231 (16%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENIS-VAIESDMHMYC 692 P F KP++ V E ++ L C + PEP + W I N IES M+ Sbjct: 257 PEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH- 315 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASL--PIVLKIKTGEKEPPQ----VIEPLKSMIV 746 L+I+ Y A+N +GE S +V+K GE + V PL + Sbjct: 316 -TLEISKCDFEDTAQYRASAMNVQGELSAYASVVVKRYKGELDESLLRGGVSMPLSFAVT 374 Query: 747 ---------------------RQGESVILSAQVVGNP-----RPTITWCKNNKPV---KA 777 R+GE++ L +VV P +P + W +N PV K Sbjct: 375 PYGYASKVEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGAPVSPSKW 434 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + GD ++T K +DEG+YT++ E + SA + V + E Sbjct: 435 VQPHWSGDRATLTFSHLNK-EDEGLYTIRVRMGEYYEQYSAYVFVRDADAE 484 Score = 42.7 bits (96), Expect = 0.11 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 6/102 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN--ITKT 1436 P PP + E+ +S+ + W P +G + + Y V+ +E + W + I Sbjct: 1020 PGPPHSVKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNK 1079 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 +Q LK + Y FR AVN+ + S+ V+ ET+ Sbjct: 1080 YLRVQGLKEGTCYVFRVRAVNQAGVGKPSDLAG--PVVAETR 1119 Score = 42.7 bits (96), Expect = 0.11 Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE-KTSVIRIKELKRSHSSKYTIEASNT 1650 +T + G PPPEV W KN L +D ++ + KT+ I + + S KY + N Sbjct: 1573 LTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNK 1632 Query: 1651 AGTSSVEVTLKVY 1663 G+ + + T+ V+ Sbjct: 1633 YGSETSDFTVSVF 1645 Score = 42.3 bits (95), Expect = 0.14 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 10/124 (8%) Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++R N+ G + VT+ LD P PGK +S+ + W+E + Sbjct: 689 FRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESRDA--KE 746 Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ Y +E + + +W N + ++ + L T SY FR AVN +S+ S+ +E Sbjct: 747 LVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVNAAGLSEYSQDSE 806 Query: 1470 YYKV 1473 +V Sbjct: 807 AIEV 810 Score = 41.1 bits (92), Expect = 0.33 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 6/95 (6%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN----NEIISPSETITQNFDGENI 888 P FI + + TV EK +KL V P P +TWY+N N +P + I ++ G + Sbjct: 257 PEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMH- 315 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 L I+ D E D+ Y+ A N G+ S A V + Sbjct: 316 TLEISKCDFE-DTAQYRASAMNVQGELSAYASVVV 349 Score = 39.9 bits (89), Expect = 0.75 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GENIELVITNVDSEID 900 +T++E + L V +P P ++W +N + ++ + + F+ G+ I+ V S D Sbjct: 1563 VTIQEGKALNLTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGV-STAD 1621 Query: 901 SGDYKCVASNSAGKSSHGARVTI 923 SG Y V N G + V++ Sbjct: 1622 SGKYGLVVKNKYGSETSDFTVSV 1644 >UniRef50_UPI0000ECA0F8 Cluster: Neurofascin precursor.; n=3; Gallus gallus|Rep: Neurofascin precursor. - Gallus gallus Length = 1249 Score = 109 bits (262), Expect = 8e-22 Identities = 80/319 (25%), Positives = 144/319 (45%), Gaps = 22/319 (6%) Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 +Q V G D+LLEC +P PDI W KG E+ A ++ + + L+I+NV Sbjct: 271 SQMVLRGVDLLLECIASGVPAPDIMWYKKGGELP-------AGKTKLENFNKALRISNVS 323 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + G Y +A N+ G I +++K P ++ +++I+ GE L + GN Sbjct: 324 EEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEPQNLILAPGEDGRLVCRANGN 379 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENSEGIAETSAVI 820 P+P+I W N +P++ P + TI+ + ++ VY A N G +A + Sbjct: 380 PKPSIQWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFV 439 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 +V + P + R Q I V + +L +P+P++ W++N + Sbjct: 440 SVLD-----VPPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNY 494 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + + ++E+ + + D G Y CVA+N GK A+V ++V+ T + + Sbjct: 495 KAHENGSLEMSMARKE---DQGIYTCVATNILGKVE--AQVRLEVKDPTRIVRGPEDQVV 549 Query: 941 EEGKTVILECQTSHTVSTK 959 + G L C+ H + K Sbjct: 550 KRGSMPRLHCRVKHDPTLK 568 Score = 76.2 bits (179), Expect = 9e-12 Identities = 77/295 (26%), Positives = 122/295 (41%), Gaps = 27/295 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV-PDENISVAIESDMHMYC 692 P + +P+ + G D L CR P+P I WL GE I N S + D ++ Sbjct: 353 PYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPPNPSREVAGDTIVF- 411 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751 + Q G+ V N E + + PP+++ P +I V Q Sbjct: 412 --------RDTQIGSSAVYQCNASNEHGYLLANAFVSVLDVPPRILAPRNQLIKVIQYNR 463 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L G+P PT+ W KN + + + + +D+G+YT A N Sbjct: 464 TRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEMSMARKEDQGIYTCVATNIL 523 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI-KLVARVTRNPV--PSITWYR 868 G E + V++PT I R E V ++G++ +L RV +P ++TW + Sbjct: 524 GKVEAQVRLEVKDPTR--------IVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLK 575 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ + + + DG L I V +E D GDY CVAS K S A +T+ Sbjct: 576 DDAPLYIGNRMKKEDDG----LTIYGV-AEKDQGDYTCVASTELDKDSAKAYLTV 625 Score = 68.1 bits (159), Expect = 2e-09 Identities = 162/814 (19%), Positives = 294/814 (36%), Gaps = 63/814 (7%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + RG D+ L P P+ W + K TK +++ + +L I V D+G Y Sbjct: 274 VLRGVDLLLECIASGVPAPDIMWYKKGGELPAGK-TK--LENFNKALRISNVSEEDSGEY 330 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYV 1416 N G ++V + P +P IL +C N I ++ Sbjct: 331 FCLASNKMGSIRHTISVRVKAAPYWLDEPQNLILAPGEDGRLVC---RANGNPKPSIQWL 387 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 V + I+ + + + ++ + SS ++ A NE A+ V Sbjct: 388 VNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDV--P 445 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXX 1534 +I +P + +K I L C F G P P + W+++G+ Y+ Sbjct: 446 PRILAPR-NQLIKVIQYNRTR---LDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGS 501 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y C+A N G+VE + ++ I ED Q K G + Sbjct: 502 LEMSMARKEDQGIYTCVATNILGKVEAQVRLEVKDPTRIVRGPED--QVVKRGSMPRLHC 559 Query: 1595 VIEGIPPPE--VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 ++ P + V W K+ L K++ + I + YT AS Sbjct: 560 RVKHDPTLKLTVTWLKDDAPLYIGNRM----KKEDDGLTIYGVAEKDQGDYTCVASTELD 615 Query: 1653 TSSVEVTLKVY-------DKPSKPEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 S + L V +KP +P+ P + + +++ SV + W P DD +T Y + Sbjct: 616 KDSAKAYLTVLALPITPAEKPERPDRPRDLELSDLAERSVKLTWIPG-DDNNSPITDYIV 674 Query: 1704 EKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EALESEPIVI 1760 + E W + +V + + L+ Y FRVIA N VG S ++ SE Sbjct: 675 QFEEDRFQPGTWHNHSRYPGNVNS-ALLSLSPYVNYQFRVIAVNDVGSSLPSMPSER--Y 731 Query: 1761 KTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVEIKQEGKK--WKXXX 1817 +T+ P ++ ITW P + P + Y V ++ + W Sbjct: 732 QTSGARPEINPTGVQGAGTQKNNMEITWTPLNATQAYGPNLRYIVRWRRRDPRGSWYNET 791 Query: 1818 XXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 + I Y+ ++ A N+ G + P + I P + P + + Sbjct: 792 VKAPRHV-VWNTPIYVPYEIKVQAENDFGRA-P-EPETYIGYSGEDYPKAAPTDVRIRVL 848 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDE-I 1936 S ++ L WT + I + E++ + + + + S + +++ I Sbjct: 849 NSTAIALTWTRVHLD---TIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGI 905 Query: 1937 IFRISAENTVGVSLPT-----ESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGT 1989 + R+ + + + + +++ T P++P L IR + W Sbjct: 906 VSRLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRYLRIRQPNLESINLEWDH 965 Query: 1990 PEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 PE G L GYN+ + + +KT V N +F ++ Y + AR ++ Sbjct: 966 PEHPNGV-LTGYNLRYQAFNGSKTGRTLVENFSPNQTRFTVQRTDPISRYRFFLRARTQV 1024 Query: 2048 GLSEPLESDEPFKVIPGEG---SHADEEPGEQTE 2078 G E + + P + G G D+ G +TE Sbjct: 1025 GDGEVIVEESPALLNEGFGFPEPQLDKGRGNKTE 1058 Score = 62.5 bits (145), Expect = 1e-07 Identities = 82/417 (19%), Positives = 161/417 (38%), Gaps = 35/417 (8%) Query: 1287 PPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 PP I ++Y + ++ + + + P P W N K K K S+ +S +L Sbjct: 39 PPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKDPKVSMRRRSGTL 98 Query: 1346 TIK-----KVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPS-PPGKPNILEIDSSS-I 1397 I + ++ + G Y+ N+ G A ++++ + P P K +++E+D + + Sbjct: 99 VIDFHGGGRPDDYE-GEYQCFARNDYGTALSSKIHLQVSRSPLWPKEKVDVIEVDEGAPL 157 Query: 1398 NICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNSSYRFRAY 1454 ++ + P I + + I + +S ++ + +Q+ +T+ S R + Sbjct: 158 SLQCNPPPGLPPPVIFWMSSSMEPIHQDKRVSQGQNGDLYFSNVMLQDAQTDYSCNARFH 217 Query: 1455 AVNEVDISDA-SETTEYYKVIKETKIQSPTVEKPLKNIT-TEPN---------------- 1496 + + + + + K ET +++ T + +T T P+ Sbjct: 218 FTHTIQQKNPYTLKVKTKKPHNETSLRNHTDMYSARGVTETTPSFMYPYGTSSSQMVLRG 277 Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFND 1555 D+ L CI GVP P + WY+ G +L K EN Y C+A N Sbjct: 278 VDLLLECIASGVPAPDIMWYKKGGELPAGKTKLENFNKALRISNVSEEDSGEYFCLASNK 337 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G + + V ++ P +++ G++ + G P P + W NG +E Sbjct: 338 MGSIRHTISVRVKAAPYWLDEPQNLIL--APGEDGRLVCRANGNPKPSIQWLVNGEPIEG 395 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 N + + I ++ + S+ Y ASN G + V D P + P Sbjct: 396 SPP-NPSREVAGDTIVFRDTQIGSSAVYQCNASNEHGYLLANAFVSVLDVPPRILAP 451 Score = 57.6 bits (133), Expect = 4e-06 Identities = 107/488 (21%), Positives = 181/488 (37%), Gaps = 57/488 (11%) Query: 1046 DVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102 D++W ++ GE+ K +F K L I N S D GEY C+ ++ + T+ Sbjct: 293 DIMWYKKGGELPAGKTKLENFNKA-----LRISNVSEEDSGEYFCLASNKMGSIRHTISV 347 Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKK 1160 V+ P + QN + G ++W +G I+ S + + Sbjct: 348 RVKAAPYWLDEPQNLILAPGEDGRLVCRANGNPKPSIQWLVNGEPIEGSPP-NPSREVAG 406 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 + D + + Y C N + + L +P IL P N ++ Sbjct: 407 DTIVFRDTQIGSSAVYQCNASNEHGYLLAN----AFVSVLDVPPRILAPRN-QLIKVIQY 461 Query: 1221 PDETLD----------VTWYKK-KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 LD + W+K + + D + + + RK +DQ YTCV Sbjct: 462 NRTRLDCPFFGSPIPTLRWFKNGQGNMLDGGNYKAHENGSLEMSMARK---EDQGIYTCV 518 Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSK 1326 + + +V + V+ P +IV + +KRGS L V + + W+ + Sbjct: 519 ATNILGKVEAQVRLEVKDPTRIVRGPEDQVVKRGSMPRLHCRVKHDPTLKLTVTWLKDDA 578 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL-------D 1379 + K D LTI V D G Y + +T+L + Sbjct: 579 PLYIGNRMKKEDDG----LTIYGVAEKDQGDYTCVASTELDKDSAKAYLTVLALPITPAE 634 Query: 1380 KPSPPGKPNILEIDS---SSINICWDEPENTGNSTIIYYVVEYQE--IDTTEWISVKNIT 1434 KP P +P LE+ S+ + W P + NS I Y+V+++E W + Sbjct: 635 KPERPDRPRDLELSDLAERSVKLTWI-PGDDNNSPITDYIVQFEEDRFQPGTWHNHSRYP 693 Query: 1435 -KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV------IKETKIQSPTVEKP 1487 +++ +L +Y+FR AVN+V S S +E Y+ I T +Q +K Sbjct: 694 GNVNSALLSLSPYVNYQFRVIAVNDVGSSLPSMPSERYQTSGARPEINPTGVQGAGTQKN 753 Query: 1488 LKNITTEP 1495 IT P Sbjct: 754 NMEITWTP 761 Score = 36.7 bits (81), Expect = 7.0 Identities = 29/136 (21%), Positives = 59/136 (43%), Gaps = 5/136 (3%) Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + +E P + P + ++ V + I + NPVP+ +W RN + + ++ Sbjct: 27 ISAIEVPLDLPQPPTITKQSVKDYIVDPRDNIFIECEAKGNPVPTFSWTRNGKFFNVAKD 86 Query: 879 ITQNFDGENIELVIT-NVDSEID--SGDYKCVASNSAGKSSHGARVTIDVEK-VTFVKHL 934 + + LVI + D G+Y+C A N G ++ +++ + V + + K Sbjct: 87 PKVSMRRRSGTLVIDFHGGGRPDDYEGEYQCFARNDYG-TALSSKIHLQVSRSPLWPKEK 145 Query: 935 QKSYETEEGKTVILEC 950 E +EG + L+C Sbjct: 146 VDVIEVDEGAPLSLQC 161 Score = 36.3 bits (80), Expect = 9.2 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC G P P I W+++ + P+ ++ ++ N A L I V ED+G + C Sbjct: 277 GVDLLLECIASGVPAPDIMWYKKGGEL-PAGKTKL--ENFNKA-LRISNVSEEDSGEYFC 332 Query: 584 VAKNAAGFASSTTELIVEA 602 +A N G T + V+A Sbjct: 333 LASNKMGSIRHTISVRVKA 351 >UniRef50_Q4STB0 Cluster: Chromosome 11 SCAF14249, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 11 SCAF14249, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 673 Score = 109 bits (262), Expect = 8e-22 Identities = 80/318 (25%), Positives = 140/318 (44%), Gaps = 17/318 (5%) Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRES 1682 + EK+ K K + ++ Y E T G S + TL + DKP++P+GPV + E + S Sbjct: 86 SSEKSEGRWYKNGKLADAALYHFE---TEGRKS-QATLAIQDKPTQPQGPVDVTESAVTS 141 Query: 1683 VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVI 1742 V +WKPP D GG ++ Y IE+ + N+W V +V ++ ++ +Y +R+ Sbjct: 142 VEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRIR 201 Query: 1743 AQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDY 1802 A+N G S+ LE+E I L P + + +TW NGG+ I+ Y Sbjct: 202 AKNAEGVSDYLETEDI-SAGVLRYPGPPSAPKVASTF-KDHINLTWSCPCDNGGTKILGY 259 Query: 1803 KVEIKQEGKK-WKXXXX---XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT 1858 +E K++G W ++ + Y+FR+ A N GT P D + Sbjct: 260 NLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPSIPCDTVI 319 Query: 1859 IGKTLTPPSQPRNFVVSES---TSRSVTLKWTEPESNGG--SPITNYIIEFKTVKGKSWT 1913 L PP + + + + + +L W +P G Y +E + V+ W Sbjct: 320 ARDPLKPPG--KGYQIESNILWIYTTFSLAWMKPREIKGQEDEAQGYYVEIRPVESLQWI 377 Query: 1914 KIVTVGGSVHEHCIENIK 1931 + +V ++ + + +K Sbjct: 378 RCNSVSTTLTSYSVRGLK 395 Score = 87.0 bits (206), Expect = 5e-15 Identities = 58/191 (30%), Positives = 91/191 (47%), Gaps = 8/191 (4%) Query: 1866 PSQPRNFV-VSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P+QP+ V V+ES SV KW P+ GG ++ Y+IE + V W+ + V GS Sbjct: 125 PTQPQGPVDVTESAVTSVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPS 184 Query: 1925 HCIENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 ++ + +RI A+N GVS L TE S + ++ P PP+AP +I Sbjct: 185 FKDSDVDPGRKYCYRIRAKNAEGVSDYLETEDISAGVLRY---PGPPSAPKVASTFKDHI 241 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRI 2041 +T W P +GG +LGYN+ + W V + + + ++D+ E Y R+ Sbjct: 242 NLT-WSCPCDNGGTKILGYNLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRV 300 Query: 2042 YARNEIGLSEP 2052 A N G +P Sbjct: 301 SAINLSGTGDP 311 Score = 83.4 bits (197), Expect = 6e-14 Identities = 65/280 (23%), Positives = 113/280 (40%), Gaps = 22/280 (7%) Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 + Y A P P W + KH + K + L I E TD+GIY + ++N G Sbjct: 397 MASYWASPLPEVTWFKDG--FPMPKHVTITNYDKGSQLLIPTSEWTDSGIYTINVKNIVG 454 Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 + V + D P PPG + + ++ I W + ++Y+V+ ++ W Sbjct: 455 QESFNIEVKVTDDPKPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTW 514 Query: 1428 ISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK-------- 1478 +V N+ + ++ N+ Y FR +A N++ +S SE + +++ KE + Sbjct: 515 KTVADNLFNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSE-SPVFEIKKEKEKPSINMLK 573 Query: 1479 -----IQS-PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 +QS P+ PL+ + ++C G P P VTWY + L T Y Sbjct: 574 KKSLDLQSPPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYITN 633 Query: 1533 X----XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 YK + N G E+S V+ ++ Sbjct: 634 VCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESSMVMNVR 673 Score = 82.6 bits (195), Expect = 1e-13 Identities = 55/169 (32%), Positives = 79/169 (46%), Gaps = 4/169 (2%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P PEV W+K+G + K IT +K S + I + + S YTI N G S + Sbjct: 404 PLPEVTWFKDGFPMP--KHVTITNYDKGSQLLIPTSEWTDSGIYTINVKNIVGQESFNIE 461 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADV 1719 +KV D P KP GPV + + +VTI W D+ + Y ++K + W VAD Sbjct: 462 VKVTDDP-KPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTWKTVAD- 519 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768 + + + + EY FRV A+N +G S ES IK + PS Sbjct: 520 NLFNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSESPVFEIKKEKEKPS 568 Score = 70.9 bits (166), Expect = 4e-10 Identities = 63/263 (23%), Positives = 106/263 (40%), Gaps = 11/263 (4%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARIQKLSINT--TYQFRI 1839 SV W P + GG + Y +E +Q G+ KW + ++ Y +RI Sbjct: 141 SVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRI 200 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A+N G S Y + I+ G L P P V+ + + L W+ P NGG+ I Sbjct: 201 RAKNAEGVS-DYLETEDISAG-VLRYPGPPSAPKVASTFKDHINLTWSCPCDNGGTKILG 258 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHE--HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 Y +E K KG ++ +V G + + + ++++ E FR+SA N G P+ Sbjct: 259 YNLE-KKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPSIPCDT 317 Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMT-SWGTPEWDGGAP--LLGYNIAIRDVTKTMWM 2014 + + P +E ++ + +W P G GY + IR V W+ Sbjct: 318 VIARDPLKPPGKGYQIESNILWIYTTFSLAWMKPREIKGQEDEAQGYYVEIRPVESLQWI 377 Query: 2015 EVGKVDVNTLKFNIRDLSENHTY 2037 V +++R L +Y Sbjct: 378 RCNSVSTTLTSYSVRGLKAMASY 400 Score = 52.4 bits (120), Expect = 1e-04 Identities = 34/132 (25%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI 1399 KS K + DA +Y E A + I DKP+ P P ++ E +S+ Sbjct: 89 KSEGRWYKNGKLADAALYHFETEGRKSQA----TLAIQDKPTQPQGPVDVTESAVTSVEF 144 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQ--NLKTNSSYRFRAYAVN 1457 W P++ G T+ YV+E +++ +W +V + + S + ++ Y +R A N Sbjct: 145 KWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPSFKDSDVDPGRKYCYRIRAKN 204 Query: 1458 EVDISDASETTE 1469 +SD ET + Sbjct: 205 AEGVSDYLETED 216 Score = 52.4 bits (120), Expect = 1e-04 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 1358 YKLRLENNCGHADV----EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 Y++R +N G +D +++ +L P PP P + IN+ W P + G + I+ Sbjct: 198 YRIRAKNAEGVSDYLETEDISAGVLRYPGPPSAPKVASTFKDHINLTWSCPCDNGGTKIL 257 Query: 1414 YYVVEYQEIDTTEWISVKN---ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 Y +E ++ T W V IT T +++++ ++Y FR A+N D S Sbjct: 258 GYNLEKKKKGTNYWSLVNQRGPITDTNYTVKDVFEGAAYEFRVSAINLSGTGDPS 312 Score = 51.6 bits (118), Expect = 2e-04 Identities = 27/92 (29%), Positives = 43/92 (46%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P+ P P+++ V W P+ GG + Y I R V + W VG+V + Sbjct: 125 PTQPQGPVDVTESAVTSVEFKWKPPKDCGGCTVSAYVIERRQVGRNKWSNVGEVPGSNPS 184 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 F D+ Y RI A+N G+S+ LE+++ Sbjct: 185 FKDSDVDPGRKYCYRIRAKNAEGVSDYLETED 216 Score = 49.6 bits (113), Expect = 0.001 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 3/116 (2%) Query: 710 VVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW 768 V + +E E +LK K+ + + PP PL+ + QG +S + G+P P +TW Sbjct: 557 VFEIKKEKEKPSINMLKKKSLDLQSPPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTW 616 Query: 769 CKNNKPVKALPTKSDGDTHSI-TILKPK-KVKDEGVYTLKAENSEGIAETSAVITV 822 NN + + + ++L PK KD G Y + EN G AE+S V+ V Sbjct: 617 YLNNISLNTNTNYYITNVCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESSMVMNV 672 Score = 49.6 bits (113), Expect = 0.001 Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 3/110 (2%) Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 KK EK + + +K + + QS P F LR P G C ++G P P +TW+ Sbjct: 561 KKEKEK-PSINMLKKKSLDLQS-PPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYL 618 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 + + ++ + + V +L+I +V P+D G + V +N G A S+ Sbjct: 619 NNISLNTNTNYYI-TNVCGVCSLLIPKVSPKDGGEYKVVVENKLGTAESS 667 Score = 46.8 bits (106), Expect = 0.007 Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 7/122 (5%) Query: 1934 DEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 D I+ I+ +N VG +S +E T P P+++ V SW + + Sbjct: 441 DSGIYTINVKNIVG------QESFNIEVKVTDDPKPPGPVKLDQNILGTVTISWLSSPDE 494 Query: 1994 GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 L Y + RD K W V N KF + ++ Y R++A+N+IGLS P Sbjct: 495 KRDDRLHYLVKKRDSFKRTWKTVADNLFNN-KFTVVNVLPGREYHFRVFAKNDIGLSPPS 553 Query: 2054 ES 2055 ES Sbjct: 554 ES 555 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 1/107 (0%) Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGG 1920 K P P + ++ +VT+ W +Y+++ + ++W K V Sbjct: 463 KVTDDPKPPGPVKLDQNILGTVTISWLSSPDEKRDDRLHYLVKKRDSFKRTW-KTVADNL 521 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 ++ + N+ E FR+ A+N +G+S P+ES ++K PS Sbjct: 522 FNNKFTVVNVLPGREYHFRVFAKNDIGLSPPSESPVFEIKKEKEKPS 568 Score = 39.1 bits (87), Expect = 1.3 Identities = 20/76 (26%), Positives = 32/76 (42%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ I+G P P V WY N L + Y IT + I ++ +Y + Sbjct: 597 GYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYITNVCGVCSLLIPKVSPKDGGEYKVV 656 Query: 1647 ASNTAGTSSVEVTLKV 1662 N GT+ + + V Sbjct: 657 VENKLGTAESSMVMNV 672 Score = 38.3 bits (85), Expect = 2.3 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+FS + +G + + C + P P + W + + N + +++ C Sbjct: 582 PPSFSVPLRRHVAPQGYECSMSCAIKGDPTPHVTWYLNNISLNTNTNYYI---TNVCGVC 638 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 S+L I V G Y VV N+ G A +V+ ++ Sbjct: 639 SLL-IPKVSPKDGGEYKVVVENKLGTAESSMVMNVR 673 >UniRef50_A6H8Q3 Cluster: Zgc:165344 protein; n=9; Clupeocephala|Rep: Zgc:165344 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 529 Score = 108 bits (260), Expect = 1e-21 Identities = 76/317 (23%), Positives = 149/317 (47%), Gaps = 22/317 (6%) Query: 1277 TKLKVEVVEFPP-KIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 T L EVV+ P ++ + R+ +K+ G + L++ + PQP W + + I K Sbjct: 209 TVLVREVVDRPKIRLPRFLRQRYVKKVGEKINLVIPFGGKPQPVVSWTKDGQPIDTKKVN 268 Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + D K + I+ E D+G+Y++ ++ + ++ + I++ P PP I++ Sbjct: 269 IRNSD-KDSIFFIRAAERVDSGVYEMCVKVDSFEDKAQLTLQIIELPGPPASVKIVDTWG 327 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRA 1453 ++ + W EP++ GN+TI Y ++ + T +W +V ++ + +I +L ++Y FR Sbjct: 328 FNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNATISDLIMGNTYIFRV 387 Query: 1454 YAVNEVDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIE 1500 + N+ IS + TT+ I++T I ++P P+++ +T + + Sbjct: 388 FTENKCGISQEATTTKTSATIQKTGIDYKPPVYKEHDFSEAPKFTTPMQDRSTTVGYNTK 447 Query: 1501 LTCIFGGVPQPKVTWYRD----GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 L C G P+PK+ W ++ G K + + Y C A N+H Sbjct: 448 LLCAVRGFPKPKIEWLKNQMIIGDDPKFRQINNQGICSLEIRKPGNFDGGVYSCRAKNEH 507 Query: 1557 GEVETSCVVGIQQKPVI 1573 GE +C + ++Q PVI Sbjct: 508 GEAVVTCKLEVKQ-PVI 523 Score = 72.5 bits (170), Expect = 1e-10 Identities = 53/211 (25%), Positives = 96/211 (45%), Gaps = 9/211 (4%) Query: 1560 ETSCVVGIQQKPVITISNEDIKQKH--KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 +T V + +P I + ++Q++ KVG++ + G P P V W K+G ++ K Sbjct: 208 DTVLVREVVDRPKIRLPRF-LRQRYVKKVGEKINLVIPFGGKPQPVVSWTKDGQPIDT-K 265 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 + NI +K S+ I+ +R S Y + + ++TL++ + P P I+ + Sbjct: 266 KVNIRNSDKDSIFFIRAAERVDSGVYEMCVKVDSFEDKAQLTLQIIELPGPPASVKIV-D 324 Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 +V +EW P D+G +T Y I+K + W V + + I L Y Sbjct: 325 TWGFNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNA-TISDLIMGNTY 383 Query: 1738 MFRVIAQNPVGFSE---ALESEPIVIKTALD 1765 +FRV +N G S+ ++ + KT +D Sbjct: 384 IFRVFTENKCGISQEATTTKTSATIQKTGID 414 Score = 64.9 bits (151), Expect = 2e-08 Identities = 44/159 (27%), Positives = 70/159 (44%), Gaps = 10/159 (6%) Query: 1381 PSPPGKP---NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435 P P +P + +++ +S+ I W P GNS + YVVE + T +W + Sbjct: 115 PEPTSEPLELGVEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVS 174 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDIS---DASETTEYYKVIKETKIQSPTVEKPLKNIT 1492 + I+N T R A+N S ++T +V+ KI+ P + + Sbjct: 175 CRYVIKNQTTGDRLNIRVVAMNPGGRSPPATLADTVLVREVVDRPKIRLPRFLR--QRYV 232 Query: 1493 TEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 + E I L FGG PQP V+W +DG+ + T K N Sbjct: 233 KKVGEKINLVIPFGGKPQPVVSWTKDGQPIDTKKVNIRN 271 Score = 58.8 bits (136), Expect = 2e-06 Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 10/276 (3%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXXXXAR--IQKLSINTTY 1835 +++ SV I+W P G S + Y VE+ +EG WK R I+ + Sbjct: 129 VNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVSCRYVIKNQTTGDRL 188 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 R+ A N G S P T D + + + + P + + + V K GG Sbjct: 189 NIRVVAMNPGGRSPPATLADTVLVREVVDRPKIRLPRFLRQRYVKKVGEKINLVIPFGGK 248 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 P ++ + TK V + S + I I+ + + + E V V + Sbjct: 249 P--QPVVSWTKDGQPIDTKKVNIRNS-DKDSIFFIRAAERVDSGVY-EMCVKVDSFEDKA 304 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + L+ +P PP + + G N+ + W P+ +G + GY I D W Sbjct: 305 QLTLQI-IELPGPPASVKIVDTWGFNVAL-EWTEPKDNGNTTITGYTIQKADKKTGDWFT 362 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 V + + L I DL +TY+ R++ N+ G+S+ Sbjct: 363 VLE-HYHRLNATISDLIMGNTYIFRVFTENKCGISQ 397 Score = 58.4 bits (135), Expect = 2e-06 Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 4/111 (3%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 K PV+++ + S AP F ++ + T G + C V G+P+P+I W + II Sbjct: 416 KPPVYKE---HDFSEAPKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKIEWLKNQMIIGDD 472 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 F+ ++ + +L IR+ D G ++C AKN G A T +L V+ P+ Sbjct: 473 PKFRQ-INNQGICSLEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVKQPV 522 Score = 47.6 bits (108), Expect = 0.004 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P + + ++ +V L+WTEP+ NG + IT Y I+ K W ++ ++ Sbjct: 314 PGPPASVKIVDTWGFNVALEWTEPKDNGNTTITGYTIQKADKKTGDWFTVLEHYHRLNA- 372 Query: 1926 CIENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATVPSPP 1969 I ++ + IFR+ EN G+S T S ++K PP Sbjct: 373 TISDLIMGNTYIFRVFTENKCGISQEATTTKTSATIQKTGIDYKPP 418 Score = 44.8 bits (101), Expect = 0.026 Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 3/127 (2%) Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 T T + + G P V K + E P+ P++ G + L V G P+P I Sbjct: 402 TKTSATIQKTGIDYKPPVYK-EHDFSEAPKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKI 460 Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAVITVEE 824 W KN + P + I L+ +K D GVY+ +A+N G A + + V++ Sbjct: 461 EWLKNQMIIGDDPKFRQINNQGICSLEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVKQ 520 Query: 825 PTEENAE 831 P +A+ Sbjct: 521 PVIADAD 527 Score = 41.9 bits (94), Expect = 0.19 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE-TYCIQKLNE 1733 + +++ SVTI W+PP G L Y +E + W K A+ + V Y I+ Sbjct: 126 VEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADW-KAANEELTVSCRYVIKNQTT 184 Query: 1734 NCEYMFRVIAQNPVGFS-EALESEPIVIKTALDVP 1767 RV+A NP G S A ++ ++++ +D P Sbjct: 185 GDRLNIRVVAMNPGGRSPPATLADTVLVREVVDRP 219 Score = 36.3 bits (80), Expect = 9.2 Identities = 23/87 (26%), Positives = 34/87 (39%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE 1924 P S+P V + SVT+ W P + G S + Y++E W Sbjct: 117 PTSEPLELGVEDVNDTSVTISWRPPATIGNSGLDGYVVEVCKEGTADWKAANEELTVSCR 176 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLP 1951 + I+N D + R+ A N G S P Sbjct: 177 YVIKNQTTGDRLNIRVVAMNPGGRSPP 203 Score = 36.3 bits (80), Expect = 9.2 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+ + + G + L C + P+P I WL K + I+ D+ I + CS Sbjct: 429 PKFTTPMQDRSTTVGYNTKLLCAVRGFPKPKIEWL-KNQMIIGDDPKFRQINNQG--ICS 485 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 L+I F G Y+ A N GEA + L++K Sbjct: 486 -LEIRKPGNFDGGVYSCRAKNEHGEAVVTCKLEVK 519 >UniRef50_UPI0000D576E1 Cluster: PREDICTED: similar to CG12002-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG12002-PA, isoform A - Tribolium castaneum Length = 1388 Score = 107 bits (258), Expect = 3e-21 Identities = 93/370 (25%), Positives = 162/370 (43%), Gaps = 27/370 (7%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P+++E + + + G + + + +V G+P+P+I W +++K ++ K D + ++K Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNGSLVIKH 293 Query: 795 KKVKDEGVYTLKAENSEG-IAETSAVITVEEPTEE----NAEPPLFINRFQEITVKEKGT 849 D G Y A+N +G + A + + P ++ N P + T + + Sbjct: 294 TDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTSESDPS 353 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + L + NP P+ITW RN ++ S+ ++F E+ LVI V + D G Y+C A+ Sbjct: 354 VSLHCKAFGNPHPTITWSRNGIQLTTSQ---RHFIDEDGTLVIRPVKAS-DHGTYRCDAT 409 Query: 910 NSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEI 967 NS G+ S A V ++V V F H Q + ET G T+ LEC S W+ + E+ Sbjct: 410 NSNGRISSEADVIVNVAPV-FTVHPQNT-ETTPGSTIKLECFAVGSPPPEITWFKDDLEV 467 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETI---PEFI 1020 I +G D G+ C ++ +E S + V P+FI Sbjct: 468 RSDGRLSISPDG--SSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPKFI 525 Query: 1021 RKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT 1079 K + E L + + + T + W++DG ++ + K I LYI Sbjct: 526 YKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQ----RTGRTKVSLIGNLYIYGV 581 Query: 1080 SVHDEGEYSC 1089 D+G Y C Sbjct: 582 VPDDQGRYEC 591 Score = 106 bits (254), Expect = 8e-21 Identities = 111/431 (25%), Positives = 166/431 (38%), Gaps = 45/431 (10%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555 P+ T + AP +E + GST F C+V G P+P I W R I+ + D Sbjct: 220 PLKGMTTRDFHCKAPEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNND 279 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE--LIVEAPLSDHGSEMTV 613 YD + +LVI+ D+G + C+AKN G S ++V G + Sbjct: 280 ---KYDIMDNGSLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGS- 335 Query: 614 XXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS-DILLECRLVAIPEPDIAWLFKGE 672 P F P + E + L C+ P P I W G Sbjct: 336 --------------------PVFLVTPVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGI 375 Query: 673 EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 ++ + I+ D L I VK GTY A N G S + + Sbjct: 376 QLTTSQRHF--IDED-----GTLVIRPVKASDHGTYRCDATNSNGRISSEADVIVNVA-- 426 Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 P + P ++ G ++ L VG+P P ITW K++ V++ S S + Sbjct: 427 -PVFTVHP-QNTETTPGSTIKLECFAVGSPPPEITWFKDDLEVRSDGRLSISPDGSSLQI 484 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 K D G+Y +A N G E SA + V T +PP FI + I TI+L Sbjct: 485 HNAKETDSGLYICEARNHLGFREVSAKVKV---TPLARKPPKFIYKPYNIEALVGSTIEL 541 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 + +P P I W ++ + + + G L I V + D G Y+C A N Sbjct: 542 PCKADGDPTPGIQWQKDGASLQRTGRTKVSLIGN---LYIYGVVPD-DQGRYECAAINDF 597 Query: 913 GKSSHGARVTI 923 G+S+ VT+ Sbjct: 598 GRSTASCYVTV 608 Score = 97.1 bits (231), Expect = 5e-18 Identities = 87/328 (26%), Positives = 137/328 (41%), Gaps = 27/328 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + P+ + GS + CR+ P+P I W+ +EI + + + D+ M Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNND-----KYDI-MDNG 287 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEA-SLP--IVL-----KIKTGEKEPPQVIEPLKSMI 745 L I + + G Y +A N +GE S P ++L + + G P ++ P+ Sbjct: 288 SLVIKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTT 347 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 SV L + GNP PTITW +N + + D +++P K D G Y Sbjct: 348 SESDPSVSLHCKAFGNPHPTITWSRNGIQL-TTSQRHFIDEDGTLVIRPVKASDHGTYRC 406 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A NS G + A + V P+F Q TIKL +P P IT Sbjct: 407 DATNSNGRISSEADVIVN-------VAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEIT 459 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W++++ + ++ + DG +++ I N E DSG Y C A N G A+V + Sbjct: 460 WFKDDLEVRSDGRLSISPDGSSLQ--IHNA-KETDSGLYICEARNHLGFREVSAKVKVTP 516 Query: 926 EKVTFVKHLQKSYETEE--GKTVILECQ 951 K + K Y E G T+ L C+ Sbjct: 517 LARKPPKFIYKPYNIEALVGSTIELPCK 544 Score = 73.7 bits (173), Expect = 5e-11 Identities = 47/184 (25%), Positives = 80/184 (43%), Gaps = 5/184 (2%) Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXXX 1545 P+ T+E + + L C G P P +TW R+G +L T++ + + Sbjct: 342 PVSVTTSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGTLVIRPVKASDH 401 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C A N +G + + V + PV T+ ++ + G + G PPPE+ Sbjct: 402 GTYRCDATNSNGRISSEADVIVNVAPVFTVHPQNTET--TPGSTIKLECFAVGSPPPEIT 459 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W+K+ ++ +D +I+ S ++I K + S Y EA N G V +KV Sbjct: 460 WFKDDLEVRSDGRLSIS--PDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPL 517 Query: 1666 PSKP 1669 KP Sbjct: 518 ARKP 521 Score = 73.3 bits (172), Expect = 7e-11 Identities = 58/229 (25%), Positives = 94/229 (41%), Gaps = 8/229 (3%) Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 T +I SDHG+ AD++ + P F+ P+ GS I LEC Sbjct: 390 TLVIRPVKASDHGT-YRCDATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLEC 448 Query: 656 RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 V P P+I W E+ D +S++ + S L+I N K+ G Y A N Sbjct: 449 FAVGSPPPEITWFKDDLEVRSDGRLSISPDG------SSLQIHNAKETDSGLYICEARNH 502 Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 G + +K+ ++PP+ I ++ G ++ L + G+P P I W K+ + Sbjct: 503 LGFREVSAKVKVTPLARKPPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASL 562 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 + ++ I D+G Y A N G + S +TV+E Sbjct: 563 QRTGRTKVSLIGNLYIYGVVP-DDQGRYECAAINDFGRSTASCYVTVKE 610 Score = 64.1 bits (149), Expect = 4e-08 Identities = 84/397 (21%), Positives = 148/397 (37%), Gaps = 46/397 (11%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 PE + QD E+ A+ + + + W RD + I+ +KYD G L Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDNG---SLV 290 Query: 1076 IRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATF----EIELT 1131 I++T D G Y C+ ++E + V P +I +Q+ GN + + +T Sbjct: 291 IKHTDESDSGHYECMAKNE----DGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVT 346 Query: 1132 KGDA----------------LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 ++ + W ++G ++ S + DG L I D G Sbjct: 347 TSESDPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDEDGT---LVIRPVKASDHGT 403 Query: 1176 YSCEVGNSKCTAILTVEEPSIN----FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 Y C+ NS I + + +N FT+ P +T + ++TW+K Sbjct: 404 YRCDATNSN-GRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFK 462 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD----AKSTTKLKVE-VVEF 1286 + + ++ D +L I E D Y C + + + K+KV + Sbjct: 463 DDLEVRSDGRLSISPDGS--SLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARK 520 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PPK + GS + L P P +W + +++ TK S+ +L Sbjct: 521 PPKFIYKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQRTGRTKVSL---IGNLY 577 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 I V D G Y+ N+ G + VT+ + +P Sbjct: 578 IYGVVPDDQGRYECAAINDFGRSTASCYVTVKENQNP 614 Score = 56.8 bits (131), Expect = 6e-06 Identities = 65/298 (21%), Positives = 115/298 (38%), Gaps = 26/298 (8%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PEI+ Q+ +++ G+ A F +T GD + W +D EI+ +N +D L Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVT-GDPKPSIYWMRDDKEIEMNNDKYDIMDNGS--LV 290 Query: 1165 IYDCDLDDAGEYSC-------EVGNSKCTAILTVEEPSINFTLRLPEFILVPAN---TDA 1214 I D D+G Y C EV + IL + P F++ P + +++ Sbjct: 291 IKHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFLVTPVSVTTSES 350 Query: 1215 YLTVEIPDETLD-----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 +V + + +TW + + +++ + D TL+IR D Y C Sbjct: 351 DPSVSLHCKAFGNPHPTITWSRNGIQLTTSQRHFIDED---GTLVIRPVKASDHGTYRCD 407 Query: 1270 LLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 ++ + +V V P + + GS + L P P W + + Sbjct: 408 ATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDDLEV 467 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 + + SI +SL I + TD+G+Y N+ G +V V + P K Sbjct: 468 RS--DGRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPK 523 Score = 52.8 bits (121), Expect = 1e-04 Identities = 85/398 (21%), Positives = 146/398 (36%), Gaps = 34/398 (8%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P+I++ ++ I GS P+P+ W+ + K I+ +D+ SL I Sbjct: 234 PEIMEGPQDVEISWGSTAVFTCRVTGDPKPSIYWMRDDKEIEMNNDKYDIMDN--GSLVI 291 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP-----GKPNILEIDSSSINICWD 1402 K + +D+G Y+ +N G IL +P G P L + S+ Sbjct: 292 KHTDESDSGHYECMAKNEDGEVKSRPARMILVRPDQQFRGGNGSPVFL-VTPVSVTTSES 350 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 +P S ++ T W S I T + + + + R ++ Sbjct: 351 DP-----SVSLHCKAFGNPHPTITW-SRNGIQLTTSQRHFIDEDGTLVIRPVKASDHGTY 404 Query: 1463 DASETTEYYKVIKETKI---QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 T ++ E + +P +N T P I+L C G P P++TW++D Sbjct: 405 RCDATNSNGRISSEADVIVNVAPVFTVHPQNTETTPGSTIKLECFAVGSPPPEITWFKDD 464 Query: 1520 KKLKT--AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVIT 1574 ++++ + + Y C A N G E S V + +KP Sbjct: 465 LEVRSDGRLSISPDGSSLQIHNAKETDSGLYICEARNHLGFREVSAKVKVTPLARKPPKF 524 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI---R 1631 I + + VG + +G P P + W K+G L+ T + K S+I Sbjct: 525 I-YKPYNIEALVGSTIELPCKADGDPTPGIQWQKDGASLQR------TGRTKVSLIGNLY 577 Query: 1632 IKELKRSHSSKYTIEASNTAG--TSSVEVTLKVYDKPS 1667 I + +Y A N G T+S VT+K P+ Sbjct: 578 IYGVVPDDQGRYECAAINDFGRSTASCYVTVKENQNPT 615 Score = 41.1 bits (92), Expect = 0.33 Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 473 YLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQ 532 Y+ + N+ + ++++ K+ P+ KP P F+ K GST++ C+ Sbjct: 495 YICEARNHLGF--REVSAKVKVTPLARKP--------PKFIYKPYNIEALVGSTIELPCK 544 Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 +G P P I W + A ++ + ++ + L I V P+D G + C A N G + Sbjct: 545 ADGDPTPGIQWQKDGASLQRTGRTKV----SLIGNLYIYGVVPDDQGRYECAAINDFGRS 600 Query: 593 SSTTELIVE 601 +++ + V+ Sbjct: 601 TASCYVTVK 609 >UniRef50_P23468 Cluster: Receptor-type tyrosine-protein phosphatase delta precursor; n=183; Eumetazoa|Rep: Receptor-type tyrosine-protein phosphatase delta precursor - Homo sapiens (Human) Length = 1912 Score = 107 bits (258), Expect = 3e-21 Identities = 220/1036 (21%), Positives = 393/1036 (37%), Gaps = 111/1036 (10%) Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTID- 1157 T E PP +Q G A+F + T GD + W K G ++ + D Sbjct: 18 TDAETPPRFTRTPVDQTGVSGGVASFICQAT-GDPRPKIVWNKKGKKVSNQRFEVIEFDD 76 Query: 1158 GKKQKLKIYDCDLD-DAGEYSCEVGN-----SKCTAILTVEEPSI--NF-TLRL-PEFIL 1207 G L+I D Y C N S T + + E I F T+ + P+ + Sbjct: 77 GSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKV 136 Query: 1208 VP-ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT---------LIIRK 1257 V T L + ++TW+K ++ + I ++ + L I + Sbjct: 137 VERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQ 196 Query: 1258 CTEDDQCEYTCVLLDAKST-----TKLKV----EVVEFPPKIVDYEREYRIKRGSDVTLL 1308 E DQ +Y CV ++ T L V EV PP+ + I G V + Sbjct: 197 SEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNIT 256 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH 1368 P P +W++ ++ + P D ++ + + Y + G Sbjct: 257 CVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGV 310 Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTE- 1426 + +T+ P PPG P + E ++SI + WD +GN + YY+++++ ++ E Sbjct: 311 IEAIAQITVKALPKPPGTPVVTESTATSITLTWD----SGNPEPVSYYIIQHKPKNSEEL 366 Query: 1427 WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--- 1483 + + + T+ S+ L S Y FR AVN + SE V+ +T Q+P+ Sbjct: 367 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE-----PVLTQTSEQAPSSAP 421 Query: 1484 --VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXX 1539 V+ + + TT + E G + +V + D + K + Sbjct: 422 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 481 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 K +AF G+ S IQ + + + K + E T+++ Sbjct: 482 LVPQKTYSVKVLAFTSIGDGPLSS--DIQVITQTGVPGQPLNFKAEPESE---TSILLSW 536 Query: 1600 PPPEVIWYKNGNKLEND----KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT--AGT 1653 PP N + D +E IT + TS R++ LK + + + A + G Sbjct: 537 TPPRSDTIANYELVYKDGEHGEEQRITIEPGTS-YRLQGLKPNSLYYFRLAARSPQGLGA 595 Query: 1654 SSVEVTLK-VYDKPSKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPD-- 1709 S+ E++ + + KPS P + S S+ + W+ PP++ +T+Y+I+ D Sbjct: 596 STAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGE 655 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 +++ ++ + D Y +++L + EY V A VG ES ++I+T DVPS Sbjct: 656 DDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPESLSVLIRTNEDVPSG 713 Query: 1770 XXXXXXXXXIDNESVYITW---FPSEKNG---GSPIIDYKVE------------IKQEGK 1811 +++ SV ++W P++++G G + ++E + Sbjct: 714 PPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADA 773 Query: 1812 KWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 +W+ I L T+Y + A G S K+ + T P +PR Sbjct: 774 QWEFDDTTEHDMI-ISGLQPETSYSLTVTAYTTKGDGA--RSKPKL-VSTTGAVPGKPR- 828 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE--HCIEN 1929 V++ + + ++W P G P+ Y ++F K + T+ S E + Sbjct: 829 LVINHTQMNTALIQWHPPVDTFG-PLQGYRLKFGR---KDMEPLTTLEFSEKEDHFTATD 884 Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGT 1989 I + +FR+SA N VG E + VP+ L S V SW Sbjct: 885 IHKGASYVFRLSARNKVGFG---EEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQP 941 Query: 1990 PEW-DGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P + + Y + RD+ + ME V +T + L + TY +++ A Sbjct: 942 PVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADT-TMTLTGLKPDTTYDVKVRAHTSK 1000 Query: 2048 GLSEPLESDEPFKVIP 2063 G P F+ +P Sbjct: 1001 G-PGPYSPSVQFRTLP 1015 Score = 78.2 bits (184), Expect = 2e-12 Identities = 81/307 (26%), Positives = 131/307 (42%), Gaps = 26/307 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F++ P Q G C+ P P I W KG++ V ++ V IE D Sbjct: 23 PPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKK-VSNQRFEV-IEFD-DGSG 79 Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748 SVL+I ++ E Y VA N GE S+ L + ++ P P + + +V + Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139 Query: 749 GESVILSAQVVGNPRPTITWCK---------NNKPVKALPTKSDGDT--HSITILKPKKV 797 + + GNP P ITW K NN +K L ++S G T ++ + Sbjct: 140 TRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEE 199 Query: 798 KDEGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 D+G Y A NS G ++ A + V E E PP F + G++ + Sbjct: 200 SDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVA 259 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 +P+P + W E ++P + + G N+ L + +V S +Y CVA ++ G Sbjct: 260 VGSPMPYVKWMLGAEDLTPEDDMP---IGRNV-LELNDVR---QSANYTCVAMSTLGVIE 312 Query: 917 HGARVTI 923 A++T+ Sbjct: 313 AIAQITV 319 Score = 73.7 bits (173), Expect = 5e-11 Identities = 62/230 (26%), Positives = 102/230 (44%), Gaps = 19/230 (8%) Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 +IT+ PP P VV+EST+ S+TL W +S P++ YII+ K + K Sbjct: 316 QITVKALPKPPGTP---VVTESTATSITLTW---DSGNPEPVSYYIIQHKPKNSEELYKE 369 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 + G + + + + + FR+ A N +G P+E + + A PS ++ Sbjct: 370 ID-GVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA--PSSAPRDVQA 426 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTM--WMEVGKVDVNTLKFNIRDLS 2032 RM+ S ++ W PE G + GY + D T+ + WM+ D I +L Sbjct: 427 RMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQIT--TIGNLV 483 Query: 2033 ENHTYMIRIYARNEIGLSEPLESDEPFKV---IPGEGSHADEEPGEQTEV 2079 TY +++ A IG PL SD +PG+ + EP +T + Sbjct: 484 PQKTYSVKVLAFTSIG-DGPLSSDIQVITQTGVPGQPLNFKAEPESETSI 532 Score = 65.7 bits (153), Expect = 1e-08 Identities = 76/311 (24%), Positives = 121/311 (38%), Gaps = 39/311 (12%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV-FPEDAGTFT 582 G F CQ G PRP+I W ++ + + + +DD + + L I+ + P D + Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 CVA N G S +T L V I G PT P+ Sbjct: 98 CVASNNVGEISVSTRLTV----------------------LREDQIPRGF-PTIDMGPQL 134 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC------SVLK 696 + V+ + C P+P+I W FK V N + I+ L+ Sbjct: 135 KVVERTRTATMLCAASGNPDPEITW-FKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQ 193 Query: 697 ITNVKKFQEGTYTVVAVNREG-EASLP---IVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 I ++ +G Y VA N G S P V +++ + PP+ P + + G SV Sbjct: 194 IEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSV 253 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ VG+P P + W + + T D +L+ V+ YT A ++ G Sbjct: 254 NITCVAVGSPMPYVKWMLGAEDL----TPEDDMPIGRNVLELNDVRQSANYTCVAMSTLG 309 Query: 813 IAETSAVITVE 823 + E A ITV+ Sbjct: 310 VIEAIAQITVK 320 Score = 53.2 bits (122), Expect = 8e-05 Identities = 92/435 (21%), Positives = 153/435 (35%), Gaps = 54/435 (12%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQD---FQMYYDDDNVAT-----LVIREVFPED 577 T C G P P+ITWF+ + S + + + T L I + D Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201 Query: 578 AGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFS 637 G + CVA N+AG S AP + + E+ + +PP FS Sbjct: 202 QGKYECVATNSAGTRYS-------APANLYVRELRE---------------VRRVPPRFS 239 Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 P + G + + C V P P + W+ E++ P E DM + +VL++ Sbjct: 240 IPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIGRNVLEL 291 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQGESVILS 755 +V+ Q YT VA++ G + +K K P P V E + I +S Sbjct: 292 NDVR--QSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDS---- 345 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 GNP P + +KP + + D + T + Y + I Sbjct: 346 ----GNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGR 401 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 V T E A P R + + TI + + P I YR + P Sbjct: 402 GPPSEPVLTQTSEQA--PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDP 459 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDY--KCVASNSAGKSSHGARVTIDVEKVTFVKH 933 ++ + + IT + + + Y K +A S G + + + + + Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519 Query: 934 LQKSYETEEGKTVIL 948 L E E +++L Sbjct: 520 LNFKAEPESETSILL 534 Score = 51.6 bits (118), Expect = 2e-04 Identities = 65/275 (23%), Positives = 107/275 (38%), Gaps = 22/275 (8%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP-VIMREISRESVTIEWKPP 1690 I L+ S T+ A T G + V + P P +++ + I+W PP Sbjct: 787 ISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPP 846 Query: 1691 LDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 +D G L Y ++ D + + + + +++ Y+FR+ A+N VGF Sbjct: 847 VDTFG-PLQGYRLKFGRKDMEP-LTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGSPIIDYKV--- 1804 E + E I +VP+ + SV ++W P +E+NG I Y + Sbjct: 905 EEMVKE---ISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNG--IITKYTLLYR 959 Query: 1805 EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT 1864 +I + + L +TTY ++ A G PY+ + +TL Sbjct: 960 DINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPG-PYSPSVQF---RTL- 1014 Query: 1865 PPSQ--PRNFVVSESTSRSVTLKWTEPES-NGGSP 1896 P Q +NF V SV L W PE+ N P Sbjct: 1015 PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP 1049 >UniRef50_O94779 Cluster: Contactin-5 precursor; n=52; Euteleostomi|Rep: Contactin-5 precursor - Homo sapiens (Human) Length = 1100 Score = 107 bits (257), Expect = 3e-21 Identities = 182/880 (20%), Positives = 341/880 (38%), Gaps = 72/880 (8%) Query: 1138 RWFKDGSEIQFSNHIQLT-IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI---LTVEE 1193 RW ++G+EI + + + IDG + + D+G Y C N+ + + T++ Sbjct: 134 RWLRNGTEIDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLATNTVGSILSREATLQF 191 Query: 1194 PSI-NFTLRLPEFILVPANTDAYLTVEIPDETLDV--TWYKKKS---VIEDTEKFTLISD 1247 + NF+ R + V L P + ++ +W + V ED+ +F IS Sbjct: 192 AYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRF--ISQ 249 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTK---------LKVEVV--EFPPKI-VDYER 1295 + L I K D Y C++ + + + L+ + V E+ PKI V + Sbjct: 250 -ETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPF 308 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWI-VNSKIIKKCKHTKPSIDSKSASLTIKKVENTD 1354 +G+ V + P P W+ VN I K + K A L I V+ D Sbjct: 309 TVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK-----SQAVLEIPNVQLDD 363 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 AGIY+ R EN+ G + + P K N ++DS S + W E + TG Y Sbjct: 364 AGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGS-PLRW-ECKATGKPRPTY 421 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 ++ + + V+ + I N+ + + ++ A N+ AS K++ Sbjct: 422 RWLK-NGVPLSPQSRVEMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYASAE---LKIL 476 Query: 1475 KETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-ATYENRX 1533 + + + K I ++++ + C G P+P ++W + + ++ K Sbjct: 477 --ASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDG 534 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y C N G E + +++ I ++ + + + VG+ ++ Sbjct: 535 SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPK--RTELTVGESIVLN 592 Query: 1594 --AVIEGIPPPEVIWYKNGNKLENDKE----YNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 A+ + W G ++ ++E +I + ++ + I+ + H+ +Y Sbjct: 593 CKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRV 652 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 TA + S E L V P P G VI+ EI+ + T+ W P D+ ++ Y ++ Sbjct: 653 QTTADSVSDEAELLVRGPPG-PPGIVIVEEITESTATLSWSPAADNHS-PISSYNLQARS 710 Query: 1708 PDNNRWIKVADVDR----DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 P + W V V D+E+ LN EY FRV+A NP+G + + +I+T Sbjct: 711 PFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDP-STPSRMIRTN 769 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVEIKQEGKK-WKXXXXXXX 1821 VP + I W P SE+ Y V + G + WK Sbjct: 770 EAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSS 829 Query: 1822 XXA----RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSES 1877 + R + + T ++ ++ N G P+ S + P + P + + Sbjct: 830 EASKFIYRDESVPPLTPFEVKVGVYNNKGDG-PF-SQIVVICSAEGEPSAAPTDVKATSV 887 Query: 1878 TSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 + + + W + + G P + +K ++ + + V G+ + ++ Sbjct: 888 SVSEILVAWKHIKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYH 947 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPT-APLEIR 1976 F + A N G P+ S +K SPP+ AP +R Sbjct: 948 FTVRAYNGAGYGPPSSEVSATTKK-----SPPSQAPSNLR 982 Score = 104 bits (249), Expect = 3e-20 Identities = 198/916 (21%), Positives = 352/916 (38%), Gaps = 77/916 (8%) Query: 833 PLFINRFQEI---TVKEKGTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENI 888 P+F+ +I T ++ + L V NPVPS W RN EI S+ DG Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT-- 156 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV-TFVKHLQKSYETEEGKTVI 947 +I+N DSG Y+C+A+N+ G S T+ + F + + EG+ V+ Sbjct: 157 -FIISNPSEAKDSGHYQCLATNTVG-SILSREATLQFAYLGNFSGRTRSAVSVREGQGVV 214 Query: 948 LECQT---SHTVSTKWYHNK-KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 L C S + W N+ D R I + DVG C+VK+ Sbjct: 215 LMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKN 273 Query: 1004 QETSTMLVVKETIPEFIRK---LQDFEVK-EKDVAILEVEINSETADVVWERDGE----I 1055 T+ ++ T P +R + ++E K E T + G I Sbjct: 274 TVTNARVLSPPT-PLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTI 332 Query: 1056 IKPKKNKYDFEKRGHIRK----LYIRNTSVHDEGEYSCIL---RDESCTAEVTVVELPPE 1108 K N Y + +RK L I N + D G Y C R ++ V P Sbjct: 333 TWMKVNGY-IPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPH 391 Query: 1109 IITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYD 1167 + +L + +++ G+ +E + T K RW K+G + + +++ ++G L I++ Sbjct: 392 WVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-VNG---VLMIHN 447 Query: 1168 CDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTL-RLPEFILVPANTDAYLTVEIPD 1222 + DAG Y C + G +A L + + F L +L + I+V + + + + Sbjct: 448 VNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQG 507 Query: 1223 ETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV 1281 ++W K + + ++ ++ D R L ++ D+ +Y C + + ++ Sbjct: 508 SPKPTISWKKGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIA 564 Query: 1282 EV-VEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKII---KKCKHTK 1335 + V+ P +I + + G + L + A W + + I ++ H + Sbjct: 565 SLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFE 624 Query: 1336 P-SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDS 1394 + SA L I+ + AG Y R++ E + + P PPG + EI Sbjct: 625 SIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITE 684 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN----ITKTQTSIQNLKTNS--S 1448 S+ + W P +S I Y ++ + + W +VK IT S + N Sbjct: 685 STATLSW-SPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVE 743 Query: 1449 YRFRAYAVNEVDISDAS------ETTEYYKVIKETKIQSPTVEKPLKNITTEP-NEDIEL 1501 Y FR A N + D S T E T + + + I EP +E+ + Sbjct: 744 YEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQN 803 Query: 1502 TCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 FG + + R G K K ++ ++ K +N+ G+ Sbjct: 804 GEGFGYIVAFRPNGTR-GWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPF 862 Query: 1562 SCVVGI-QQKPVITISNEDIKQKHKVGDEWLVT--AVIEGIPPP---EVIWYKNGNKLEN 1615 S +V I + + + D+K E LV + E + P EV ++K+ + Sbjct: 863 SQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVGYWKDME--QE 920 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKP-EGPVI 1674 D + T+ S + + L+ + +T+ A N AG + K S P + P Sbjct: 921 DTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSN 980 Query: 1675 MR-EISRESVTIEWKP 1689 +R E V++ W+P Sbjct: 981 LRWEQQGSQVSLGWEP 996 Score = 85.4 bits (202), Expect = 2e-14 Identities = 69/235 (29%), Positives = 107/235 (45%), Gaps = 19/235 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + +K +D GS + EC+ P P WL G + P +S + M Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSP--------QSRVEMVNG 441 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK-SMIVRQGESV 752 VL I NV + G Y +A N+ G LKI P + LK ++IV + + V Sbjct: 442 VLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASA--PTFALNQLKKTIIVTKDQEV 499 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 ++ + G+P+PTI+W K ++ V+ + S+ IL K DEG Y + EN G Sbjct: 500 VIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASK-SDEGKYVCRGENVFG 558 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 AE A ++V+EPT P + E+TV E +I L + + +T+Y Sbjct: 559 SAEIIASLSVKEPTRIELTP-----KRTELTVGE--SIVLNCKAIHDASLDVTFY 606 Score = 83.4 bits (197), Expect = 6e-14 Identities = 110/464 (23%), Positives = 184/464 (39%), Gaps = 39/464 (8%) Query: 645 VDEGSDILLECRLVA-IPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKITNVKK 702 V EG ++L C PE +W+F V +++ + ++Y S ++ ++V Sbjct: 207 VREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS 266 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 + V R P+ L+ GE EP + ++ +G +V + +G Sbjct: 267 YICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALG 326 Query: 761 NPRPTITWCKNNK--PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 NP PTITW K N P KA KS ++ + ++ D G+Y +AENS G Sbjct: 327 NPVPTITWMKVNGYIPSKARLRKS----QAVLEIPNVQLDDAGIYECRAENSRGKNSFRG 382 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 + V P ++ + + + ++ + T P P+ W +N +SP Sbjct: 383 QLQV-------YTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR 435 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF-VKHLQKS 937 + + N L+I NV ++ D+G Y+C+A N G A + I TF + L+K+ Sbjct: 436 V----EMVNGVLMIHNV-NQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKT 490 Query: 938 YETEEGKTVILEC--QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVG 995 + + V++EC Q S + W + + I+ +G D G Sbjct: 491 IIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEG 547 Query: 996 VIKC----IVKDQETSTMLVVKE-TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-- 1048 C + E L VKE T E K + V E V + I+ + DV Sbjct: 548 KYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKA-IHDASLDVTFY 606 Query: 1049 WERDGEIIKPKKNKYDFEK---RGHIRKLYIRNTSVHDEGEYSC 1089 W G+ I ++ FE + L IRN + G Y C Sbjct: 607 WTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGC 650 Score = 56.8 bits (131), Expect = 6e-06 Identities = 113/529 (21%), Positives = 201/529 (37%), Gaps = 55/529 (10%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSIT 790 +EP +I P S + V L+ +V GNP P+ W +N + + + Sbjct: 103 QEPDDIIFPTDS----DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE-ITVKE-KG 848 I P + KD G Y A N+ G I E T + A F R + ++V+E +G Sbjct: 159 ISNPSEAKDSGHYQCLATNTVG------SILSREATLQFAYLGNFSGRTRSAVSVREGQG 212 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 + + + +P +W N +E + E L I+ V + D G Y C+ Sbjct: 213 VVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTS-DVGSYICLV 271 Query: 909 SNSAGKS---SHGARVTIDVEKV------TFVKHLQKSYETEEGKTVILEC-QTSHTVST 958 N+ + S +T+ + V H + +G TV +EC + V T Sbjct: 272 KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPT 331 Query: 959 -KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKE 1014 W +++G + D G+ +C ++ + Sbjct: 332 ITW----MKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVY 387 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRK 1073 T P ++ KL D ++ E + + W ++G + P+ E + Sbjct: 388 TYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSR---VEMVNGV-- 442 Query: 1074 LYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPEI-ITRLQNQ-KVNKGNKATFE 1127 L I N + D G Y C+ ++ +AE+ ++ P + +L+ V K + E Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 502 Query: 1128 IE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGN 1182 + + W K ++ + I + DG L+I + D G+Y C G+ Sbjct: 503 CKPQGSPKPTISWKKGDRAVRENKRIAILPDG---SLRILNASKSDEGKYVCRGENVFGS 559 Query: 1183 SKCTAILTVEEPS-INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230 ++ A L+V+EP+ I T + E L + I D +LDVT+Y Sbjct: 560 AEIIASLSVKEPTRIELTPKRTE--LTVGESIVLNCKAIHDASLDVTFY 606 Score = 55.2 bits (127), Expect = 2e-05 Identities = 30/96 (31%), Positives = 47/96 (48%), Gaps = 7/96 (7%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P +VEKL GS +++EC+ G PRP W + + P +M L+ Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN-----GVLM 444 Query: 570 IREVFPEDAGTFTCVAKNAAG--FASSTTELIVEAP 603 I V DAG + C+A+N G +AS+ +++ AP Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAP 480 Score = 38.7 bits (86), Expect = 1.7 Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+TV+ EC G P P ITW + I + + A L I V +DAG + C Sbjct: 315 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLR-----KSQAVLEIPNVQLDDAGIYEC 369 Query: 584 VAKNAAGFASSTTELIV 600 A+N+ G S +L V Sbjct: 370 RAENSRGKNSFRGQLQV 386 >UniRef50_Q9W213 Cluster: CG13521-PB, isoform B; n=5; Sophophora|Rep: CG13521-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 1429 Score = 107 bits (256), Expect = 4e-21 Identities = 132/539 (24%), Positives = 222/539 (41%), Gaps = 51/539 (9%) Query: 730 GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS------D 783 G+ + P++IE ++V++ E L+ +V G P PTI W K+ +PV KS D Sbjct: 85 GQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKD 144 Query: 784 GDTHSITILKPKKVKDEGVYTLKAENSEGIAETS-AVITVEEPTEE-NAEPPLFINRFQE 841 G ++ KK +D G Y A+N G A + A + + ++ EP E Sbjct: 145 GALFFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGE 204 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT-------QNFDGENIELVITN 894 + E G K + P P++ W ++ + + ++ + DG N L+I+N Sbjct: 205 TALLECGPPKGI------PEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGN--LLISN 256 Query: 895 VDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953 V+ ID G+YKC+A N G + S A++ + V K F+K K G+T C Sbjct: 257 VEP-IDEGNYKCIAQNLVGTRESSYAKLIVQV-KPYFMKE-PKDQVMLYGQTATFHCSVG 313 Query: 954 HTVSTKWYHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTM 1009 K K+E + + I+ + + D G C + Q ++ Sbjct: 314 GDPPPKVLWKKEEGNIPVSRARILHDEK--SLEISNITPTDEGTYVCEAHNNVGQISARA 371 Query: 1010 LVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSETADVVWERDG-EIIKPKKNKYDFEK 1067 ++ P F ++ + +V V L + + V W ++G + + + + Sbjct: 372 SLIVHAPPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQH 431 Query: 1068 RGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEV-----TVVELPPEII-TRLQNQKVN 1119 L I + DEG Y C +S T V ++ E PP II NQ + Sbjct: 432 VAADGTLQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLP 491 Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 KG+ AT T + ++WF DG +Q N + I G L++ D L D+G Y+C Sbjct: 492 KGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYSI-IQG--SSLRVDDLQLSDSGTYTC 548 Query: 1179 ----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 E G + A LTVE+P R + PA + + ++ + W K + Sbjct: 549 TASGERGETSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPKVLNVSRTSISLRWAKSQ 607 Score = 91.1 bits (216), Expect = 3e-16 Identities = 87/368 (23%), Positives = 143/368 (38%), Gaps = 26/368 (7%) Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665 D G+ + A ++ + P F K+PK Q + G C + P P + Sbjct: 261 DEGNYKCIAQNLVGTRESSYAKLIVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKV 320 Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W K EE NI V+ +H S L+I+N+ EGTY A N G+ S L Sbjct: 321 LW--KKEE----GNIPVSRARILHDEKS-LEISNITPTDEGTYVCEAHNNVGQISARASL 373 Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD 785 + PP + + V V L GNP P++ W K P S G Sbjct: 374 IVHA----PPNFTKRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGR 429 Query: 786 TH----SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 H + + +DEG Y A + + ++S V + + + PP I Sbjct: 430 QHVAADGTLQITDVRQEDEGYYVCSAFS---VVDSSTVRVFLQVSSLDERPPPIIQIGPA 486 Query: 842 ITVKEKGTI-KLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 KG++ L R T NP P I W+ + + + G ++ + + D Sbjct: 487 NQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRYS-IIQGSSLRVDDLQLS---D 542 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHL--QKSYETEEGKTVILECQTSHTVST 958 SG Y C AS G++S A +T++ T + +Y G +L + ++S Sbjct: 543 SGTYTCTASGERGETSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPKVLNVSRT-SISL 601 Query: 959 KWYHNKKE 966 +W ++++ Sbjct: 602 RWAKSQEK 609 Score = 83.8 bits (198), Expect = 5e-14 Identities = 115/494 (23%), Positives = 189/494 (38%), Gaps = 62/494 (12%) Query: 501 PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYY 560 P Q +P +E C+VEG P P I WF+ + ++ Sbjct: 81 PAVRGQYQSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRV 140 Query: 561 DDDNVATLVIREV---FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXX 617 + A R + +D G + CVAKN G A S + A L D + V Sbjct: 141 QFKDGALFFYRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRD---DFRVEPKD 197 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD 677 A +LE PP +P ++ +G +P D+ K Sbjct: 198 TRVAKGETA-LLECGPPKGIPEPTLIWIKDG-----------VPLDDL----KAMSFGAS 241 Query: 678 ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG--EAS-LPIVLKIKTGEKEP 734 + + + L I+NV+ EG Y +A N G E+S +++++K Sbjct: 242 SRVRIVDGGN-------LLISNVEPIDEGNYKCIAQNLVGTRESSYAKLIVQVK------ 288 Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK--NNKPVKALPTKSDGDTHSITIL 792 P ++ K ++ G++ V G+P P + W K N PV D + I+ + Sbjct: 289 PYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLWKKEEGNIPVSRARILHDEKSLEISNI 348 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 P DEG Y +A N+ G A + V PP F R V G ++L Sbjct: 349 TP---TDEGTYVCEAHNNVGQISARASLIVH-------APPNFTKRPSNKKVGLNGVVQL 398 Query: 853 VARVTRNPVPSITWYRN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 + NP PS+ W + + ++ P+ + + + L IT+V E D G Y C A + Sbjct: 399 PCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGTLQITDVRQE-DEGYYVCSAFS 457 Query: 911 SAGKSSHGARVTIDV----EKVTFVKHLQKSYET-EEGKTVILECQTSHTVS--TKWYHN 963 S+ RV + V E+ + + + +T +G L C+ + S KW+H+ Sbjct: 458 VVDSST--VRVFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHD 515 Query: 964 KKEISGMDHREIIQ 977 + + IIQ Sbjct: 516 GHAVQAGNRYSIIQ 529 Score = 69.7 bits (163), Expect = 8e-10 Identities = 151/817 (18%), Positives = 292/817 (35%), Gaps = 78/817 (9%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL-- 1345 P+I+++ + +K+ TL + P+P EW + + + + + K +L Sbjct: 90 PRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFF 149 Query: 1346 --TIKKVENTDAGIYKLRLENNCG-----HADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 T++ + D G Y +N G HA +++ V D P + + +++ + Sbjct: 150 YRTMQGKKEQDGGEYWCVAKNRVGQAVSRHASLQIAVLRDDFRVEPKDTRVAKGETALLE 209 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWIS------VKNITKTQTSIQNLKTNSSYRFR 1452 C P+ T+I ++ + +D + +S V+ + I N++ ++ Sbjct: 210 -C-GPPKGIPEPTLI-WIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNYK 266 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A N V ++S Y K+I + K P K K+ + C GG P PK Sbjct: 267 CIAQNLVGTRESS----YAKLIVQVK---PYFMKEPKDQVMLYGQTATFHCSVGGDPPPK 319 Query: 1513 VTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 V W ++ + ++A + Y C A N+ G++ + + P Sbjct: 320 VLWKKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPP 379 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG--NKLENDKEYNITTKEKTSV 1629 T +K + + + G PPP V W K G + + + Sbjct: 380 NFT--KRPSNKKVGLNGVVQLPCMASGNPPPSVFWTKEGVSTLMFPNSSHGRQHVAADGT 437 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV---TIE 1686 ++I ++++ Y A + +S+V V L+V +P P+I + +++ ++ Sbjct: 438 LQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPP-PIIQIGPANQTLPKGSVA 496 Query: 1687 WKPPLDDGG-LELTKYAIEKHEPD-NNRW-------IKVADVD-RDVETYCIQKLNENCE 1736 P G K+ + H NR+ ++V D+ D TY E E Sbjct: 497 TLPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGE 556 Query: 1737 --YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 + + + P S ++P P + S+ + W S++ Sbjct: 557 TSWAATLTVEKPGSTSLHRAADPSTYPAPPGTPK-------VLNVSRTSISLRWAKSQEK 609 Query: 1795 GGS--PIIDYKVEIKQEGKK--W-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSL 1849 G+ PII Y VE + W I L+ T+Y F + A N G S+ Sbjct: 610 PGAVGPIIGYTVEYFSPDLQTGWIVAAQRVGDTQVTISGLTPGTSYVFLVRAENTQGISV 669 Query: 1850 P---------------YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 P S + ++ +TL S + +V L+W S Sbjct: 670 PSGLSNTIKTIEADFDAASANDLSAARTLLTGKSVELIDASAINASAVRLEWMLHVSADE 729 Query: 1895 SPITNYIIEFK--TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 + I +K +V + I + S + N+K+ + F ++ P+ Sbjct: 730 KYVEGLRIHYKDASVPSAQYHSITVMDASAESFVVGNLKKYTKYEFFLTPFFETIEGQPS 789 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW-GTPEWDGGAPLLGYNIAIRDVTKT 2011 S++ + VPS P ++I M W P L GY I + Sbjct: 790 NSKTAL--TYEDVPSAPPDNIQIGMYNQTAGWVRWTPPPSQHHNGNLYGYKIEVSAGNTM 847 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + ++ T + +L+ Y +R+ + + G Sbjct: 848 KVLANMTLNATTTSVLLNNLTTGAVYSVRLNSFTKAG 884 Score = 49.6 bits (113), Expect = 0.001 Identities = 93/490 (18%), Positives = 173/490 (35%), Gaps = 39/490 (7%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P II + V K AT ++ K + + WFKDG + + + K L Sbjct: 90 PRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGALFF 149 Query: 1166 YDC----DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT------DAY 1215 Y D GEY C N A+ S+ + +F + P +T A Sbjct: 150 YRTMQGKKEQDGGEYWCVAKNRVGQAV--SRHASLQIAVLRDDFRVEPKDTRVAKGETAL 207 Query: 1216 LTV----EIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEY 1266 L IP+ TL W K ++D + + + + R L+I D+ Y Sbjct: 208 LECGPPKGIPEPTL--IWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPIDEGNY 265 Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 C+ L+ + ++ K+ +V+ P + ++ + G T P P W Sbjct: 266 KCIAQNLVGTRESSYAKL-IVQVKPYFMKEPKDQVMLYGQTATFHCSVGGDPPPKVLW-- 322 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 K ++ I SL I + TD G Y NN G ++ + P+ Sbjct: 323 -KKEEGNIPVSRARILHDEKSLEISNITPTDEGTYVCEAHNNVGQISARASLIVHAPPNF 381 Query: 1384 PGKPNILEIDSSSINICWDEP-ENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 +P+ ++ +N P +GN + + + + T + + + + + Sbjct: 382 TKRPSNKKV---GLNGVVQLPCMASGNPPPSVFWTK-EGVSTLMFPNSSHGRQHVAADGT 437 Query: 1443 LK-TNSSYRFRAYAV-NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 L+ T+ Y V + + D+S + +V + P ++ N T Sbjct: 438 LQITDVRQEDEGYYVCSAFSVVDSSTVRVFLQVSSLDERPPPIIQIGPANQTLPKGSVAT 497 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 L C G P P++ W+ DG ++ + + Y C A + GE Sbjct: 498 LPCRATGNPSPRIKWFHDGHAVQAGNRYSIIQGSSLRVDDLQLSDSGTYTCTASGERGET 557 Query: 1560 ETSCVVGIQQ 1569 + + +++ Sbjct: 558 SWAATLTVEK 567 Score = 46.0 bits (104), Expect = 0.011 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 4/107 (3%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 VF + +S ++ PI + P GS C+ G P P+I WF ++ + Sbjct: 466 VFLQVSSLDERPPPIIQIGPANQTLPKGSVATLPCRATGNPSPRIKWFHDGHAVQAGNRY 525 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + ++L + ++ D+GT+TC A G S L VE P Sbjct: 526 SIIQG----SSLRVDDLQLSDSGTYTCTASGERGETSWAATLTVEKP 568 Score = 41.5 bits (93), Expect = 0.25 Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 29/209 (13%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXX 1538 QSP + + ++ + NE L C G P+P + W++DG+ + T K ++ + Sbjct: 88 QSPRIIEHPTDLVVKKNEPATLNCKVEGKPEPTIEWFKDGEPVSTNEKKSHRVQFKDGAL 147 Query: 1539 XXXXX-------XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C+A N G+ S +Q I + +D + + K D + Sbjct: 148 FFYRTMQGKKEQDGGEYWCVAKNRVGQA-VSRHASLQ----IAVLRDDFRVEPK--DTRV 200 Query: 1592 V---TAVIE-----GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI-----RIKELKRS 1638 TA++E GIP P +IW K+G L++ K + + ++ I ++ Sbjct: 201 AKGETALLECGPPKGIPEPTLIWIKDGVPLDDLKAMSFGASSRVRIVDGGNLLISNVEPI 260 Query: 1639 HSSKYTIEASNTAGT-SSVEVTLKVYDKP 1666 Y A N GT S L V KP Sbjct: 261 DEGNYKCIAQNLVGTRESSYAKLIVQVKP 289 >UniRef50_Q4RFP3 Cluster: Chromosome 16 SCAF15113, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF15113, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1184 Score = 106 bits (255), Expect = 6e-21 Identities = 90/341 (26%), Positives = 143/341 (41%), Gaps = 18/341 (5%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVY---DKPSKPEGPVIMREISRESVTIEWK 1688 I+ L RS K+ + A N+ G S+ +++ D+PS P PVI + S + W+ Sbjct: 511 IRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKPVIRGRVLPTSFKMAWE 570 Query: 1689 PPLDDGGLELTKYAIEKHEP-DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 PP DDGG E+TKY +E E W V + + + L C Y RV + Sbjct: 571 PPKDDGGAEITKYVVELSEGLSGVSWELV--YSGPAKEHVCEGLKPGCSYQTRVYCMSEG 628 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI- 1806 G S SE + ++T P V + W P + +GGSP+ Y VE+ Sbjct: 629 GQSPL--SETLQVQTPAVPPGTCLAPRLAGKPKAREVQLRWGPPQVDGGSPVSCYSVEMC 686 Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPP 1866 Q+ ++ + + L TY FRI A N+ G P++ ++T G P Sbjct: 687 GQQSEESREVYQGPELDCSVGGLMPGKTYSFRIKAANKAGFG-PFSERCEVTTGP--GAP 743 Query: 1867 SQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 Q + + + V + W P N G+P+T Y +E+ +G T HE Sbjct: 744 EQCKAPSIMCKSPTCVVISWEAPPCN-GAPVTEYRLEWGAAEG-CMQMCYTGPALCHE-- 799 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPS 1967 ++ + R A N GV S++V + +VP+ Sbjct: 800 MKGLSPATNYFCRTQAVNVAGVG--PFSEAVLCQTPCSVPA 838 Score = 97.9 bits (233), Expect = 3e-18 Identities = 100/405 (24%), Positives = 168/405 (41%), Gaps = 26/405 (6%) Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G S V+ P P ++ S+ ++WK P D+G ++ Y ++ E Sbjct: 340 GNPSEPVSFTTLSCEPDPPNPPRKASGTKNSLVLQWKAPCDNGS-KIQNYILQWDEGKGT 398 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 + + Y + KL+ Y FR+ A+N +G SE SE + + T+ VP Sbjct: 399 GIYEQCYYGPQKQ-YRVTKLSPASRYAFRLAAKNDMGVSEF--SEVVDLFTSCSVPLPPF 455 Query: 1772 XXXXXXXIDNESVYITWF--PSEKNGGSPIID---YKVEIKQEGKKW--KXXXXXXXXXA 1824 + E +TW ++ SP D Y +E+++EG + + Sbjct: 456 PP------ELEKAGVTWLCLKWQRPTSSPKEDDIYYILEMEEEGSGYGFQPSYDGEELTC 509 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 I+ L+ +T Y+FR+ A N G S P + IT + P +P + S + Sbjct: 510 TIRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKP--VIRGRVLPTSFKM 567 Query: 1885 KWTEPESNGGSPITNYIIEFKT-VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 W P+ +GG+ IT Y++E + G SW + + G EH E +K R+ Sbjct: 568 AWEPPKDDGGAEITKYVVELSEGLSGVSWELVYS--GPAKEHVCEGLKPGCSYQTRVYCM 625 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 + G S P S++++++ A P AP + V WG P+ DGG+P+ Y++ Sbjct: 626 SEGGQS-PL-SETLQVQTPAVPPGTCLAPRLAGKPKAREVQLRWGPPQVDGGSPVSCYSV 683 Query: 2004 AIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + EV L ++ L TY RI A N+ G Sbjct: 684 EMCGQQSEESREV--YQGPELDCSVGGLMPGKTYSFRIKAANKAG 726 Score = 58.0 bits (134), Expect = 3e-06 Identities = 38/140 (27%), Positives = 68/140 (48%), Gaps = 5/140 (3%) Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKPSPPGKPNIL- 1390 +PS D + + TI+ + + +++ N+ G ++ V ++ D+PS P KP I Sbjct: 499 QPSYDGEELTCTIRNLNRSTKYKFRVAAYNSEGKSNPSQVVELITNPDRPSSPCKPVIRG 558 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQE-IDTTEWISVKNITKTQTSIQNLKTNSSY 1449 + +S + W+ P++ G + I YVVE E + W V + + + LK SY Sbjct: 559 RVLPTSFKMAWEPPKDDGGAEITKYVVELSEGLSGVSWELVYSGPAKEHVCEGLKPGCSY 618 Query: 1450 RFRAYAVNEVDISDASETTE 1469 + R Y ++E S SET + Sbjct: 619 QTRVYCMSEGGQSPLSETLQ 638 Score = 52.0 bits (119), Expect = 2e-04 Identities = 67/263 (25%), Positives = 105/263 (39%), Gaps = 22/263 (8%) Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845 I W P N GS I Y +++ G++ IQ L +T+Y+ RI A N + Sbjct: 885 ICWDPP-CNHGSEITSYSIDL---GERQPIVIGPVTKHI-IQHLQPDTSYRIRIQALNSL 939 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEF 1904 G P++ K+ KT P QP + + +++ LKW + P S Y ++ Sbjct: 940 GAG-PFSHTFKL---KTKPLPPQPPRLECTAFSHQTLRLKWGDGPAKASTSDALQYQLQM 995 Query: 1905 KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 + G+ I G H H ++ + E FRI A N G E + T Sbjct: 996 EDKSGRF---ISLYKGPCHTHKVQRLNESTSYTFRIQAFNEAG-----EGPFSTVYTFTT 1047 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT- 2023 SPP AP++ V + + T W+ AP+ G + T E ++ Sbjct: 1048 PRSPP-APVKAPKVERHDDNSCEVT--WEALAPMRGDPVIYTLQCMTGNSEFKQLYKGPG 1104 Query: 2024 LKFNIRDLSENHTYMIRIYARNE 2046 F+I+ L N Y R+ A E Sbjct: 1105 TSFHIQSLQLNSDYRFRVCAVRE 1127 Score = 48.8 bits (111), Expect = 0.002 Identities = 55/257 (21%), Positives = 106/257 (41%), Gaps = 20/257 (7%) Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W PP + G E+T Y+I+ E + I + V + + IQ L + Y R+ A N Sbjct: 887 WDPPCNHGS-EITSYSIDLGE---RQPIVIGPVTKHI----IQHLQPDTSYRIRIQALNS 938 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVE 1805 +G + + K P ++++ + W K S + Y+++ Sbjct: 939 LGAGPFSHTFKLKTKPLPPQPPRLECTA----FSHQTLRLKWGDGPAKASTSDALQYQLQ 994 Query: 1806 IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 ++ + ++ ++Q+L+ +T+Y FRI A NE G P+++ T + +P Sbjct: 995 MEDKSGRFISLYKGPCHTHKVQRLNESTSYTFRIQAFNEAGEG-PFSTVYTFTTPR--SP 1051 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P+ + V S + W G P+ I + + G S K + G H Sbjct: 1052 PAPVKAPKVERHDDNSCEVTWEALAPMRGDPV---IYTLQCMTGNSEFKQLYKGPGTSFH 1108 Query: 1926 CIENIKEKDEIIFRISA 1942 I++++ + FR+ A Sbjct: 1109 -IQSLQLNSDYRFRVCA 1124 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 4/127 (3%) Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN-IC--WDE 1403 + K+ ++L +N+ G ++ V + S P P E++ + + +C W Sbjct: 414 VTKLSPASRYAFRLAAKNDMGVSEFSEVVDLFTSCSVPLPPFPPELEKAGVTWLCLKWQR 473 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDIS 1462 P ++ IYY++E +E + + T +I+NL ++ Y+FR A N S Sbjct: 474 PTSSPKEDDIYYILEMEEEGSGYGFQPSYDGEELTCTIRNLNRSTKYKFRVAAYNSEGKS 533 Query: 1463 DASETTE 1469 + S+ E Sbjct: 534 NPSQVVE 540 Score = 37.5 bits (83), Expect = 4.0 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 6/74 (8%) Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 S+ + ICWD P N G+ Y + ++ + I + +TK IQ+L+ ++SYR R Sbjct: 880 STCLGICWDPPCNHGSEITSYSI----DLGERQPIVIGPVTK--HIIQHLQPDTSYRIRI 933 Query: 1454 YAVNEVDISDASET 1467 A+N + S T Sbjct: 934 QALNSLGAGPFSHT 947 Score = 37.5 bits (83), Expect = 4.0 Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 7/128 (5%) Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK---PNILEIDSSSINICWDE 1403 ++++ + + ++++ N G T SPP P + D +S + W+ Sbjct: 1015 VQRLNESTSYTFRIQAFNEAGEGPFSTVYTFTTPRSPPAPVKAPKVERHDDNSCEVTWEA 1074 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 +IY + +E+ + T IQ+L+ NS YRFR AV E D Sbjct: 1075 LAPMRGDPVIYTL--QCMTGNSEFKQLYKGPGTSFHIQSLQLNSDYRFRVCAVRE--CQD 1130 Query: 1464 ASETTEYY 1471 A E + Y Sbjct: 1131 APELSGPY 1138 >UniRef50_Q58EX2 Cluster: Protein sidekick-2 precursor; n=19; Euteleostomi|Rep: Protein sidekick-2 precursor - Homo sapiens (Human) Length = 2170 Score = 106 bits (255), Expect = 6e-21 Identities = 131/588 (22%), Positives = 220/588 (37%), Gaps = 33/588 (5%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-----KATYENRXXX 1535 +P + + + T + L C G P+P +TW + + L + + T Sbjct: 399 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 458 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y C+A N G E S + + + IT +D Q G + + Sbjct: 459 LISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQD--QSVIKGTQASMVCG 516 Query: 1596 IEGIPPPEV--IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 + P + IW K+G L + I ++ + I + YT + G Sbjct: 517 VTHDPRVTIRYIWEKDGATLGTESHPRIRL-DRNGSLHISQTWSGDIGTYTCRVISAGGN 575 Query: 1654 SSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 S L+V P PE PV + + R ++ + W P DG L +Y +E E +N Sbjct: 576 DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPF-DGNSPLIRYILEMSE-NNAP 633 Query: 1713 W-IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 W + +A VD + ++ L Y FR+ A N VG + + + + P+ Sbjct: 634 WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ-FSKDTERVSLPEEPPTAPP 692 Query: 1772 XXXXXXXIDNESVYITWFP---SEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826 N+S+ I W P S +NG II Y + G ++K + Sbjct: 693 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLL 752 Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST-SRSVTLK 1885 + L I T Y+ + A N G + Y+S K+T P+ P V +E+T S ++ Sbjct: 753 EDLIIWTNYEIEVAAYNSAGLGV-YSS--KVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 809 Query: 1886 WTEPESNGGSPITN--YIIEFKTVKGKSWTKIV---TVGGSVHEHCIENIKEKDEIIFRI 1940 W P + I +I ++ + + T + S+H + +K+ E + Sbjct: 810 WNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV 869 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 T G + Q VR H VP P L + + SW P G L G Sbjct: 870 LCFTTPGDGPRSTPQLVR--THEDVPG-PVGHLSFSEILDTSLKVSWQEPGEKNGI-LTG 925 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 Y I+ + +T + TL++ + L+ TY I + A G Sbjct: 926 YRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKG 973 Score = 87.0 bits (206), Expect = 5e-15 Identities = 110/522 (21%), Positives = 199/522 (38%), Gaps = 32/522 (6%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT---YENRXXXXXXXX 1540 V++P ++IT E + +++ C GVP P +TWY+D ++ K T N Sbjct: 309 VKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGL 368 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 ++C A N GEV+TS + + P IT D G ++ G Sbjct: 369 VPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVID--GMSVVLACETSGA 426 Query: 1600 PPPEVIWYKNGNKLENDKEY--NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 P P + W K L + T E S++ I S + YT A+N+ G Sbjct: 427 PRPAITWQKGERILASGSVQLPRFTPLESGSLL-ISPTHISDAGTYTCLATNSRGVDEAS 485 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD-NNRWIKV 1716 L V+ + + P I ++ D +Y EK Sbjct: 486 ADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDP--RVTIRYIWEKDGATLGTESHPR 543 Query: 1717 ADVDRDVETYCIQKLNENC-EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 +DR+ + Q + + Y RVI+ G +++ S + ++ P Sbjct: 544 IRLDRNGSLHISQTWSGDIGTYTCRVIS---AGGNDS-RSAHLRVRQLPHAPE--HPVAT 597 Query: 1776 XXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXX---XXXXARIQKLSIN 1832 ++ ++ +TW +G SP+I Y +E+ + W ++ L Sbjct: 598 LSTVERRAINLTW-TKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPA 656 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW-TEPES 1891 +YQFR+ A N++G +++++ + P + P+N + S T++S+ ++W PES Sbjct: 657 RSYQFRLCAVNDVGKGQFSKDTERVSLPEE-PPTAPPQNVIASGRTNQSIMIQWQPPPES 715 Query: 1892 NGGSPITNYIIEFKTV---KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 + + YII + G + I V+ +E++ ++A N+ G Sbjct: 716 HQNGILKGYIIRYCLAGLPVGYQFKNI--TDADVNNLLLEDLIIWTNYEIEVAAYNSAG- 772 Query: 1949 SLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 L S V VP+ P + S + +W P Sbjct: 773 -LGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAP 813 Score = 85.8 bits (203), Expect = 1e-14 Identities = 98/425 (23%), Positives = 175/425 (41%), Gaps = 50/425 (11%) Query: 1658 VTLKVYDKPSKPEGPVIMRE-ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW-IK 1715 VT + D+P P P++ +E + SV + W+P DG + Y I+ E + RW + Sbjct: 1390 VTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSPVRYYTIQTRELPSGRWALH 1448 Query: 1716 VADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXX 1775 A V + ++ + +L Y FRV A N +G SE E E + T P Sbjct: 1449 SASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE-ESESLTTLQAAPDEAPTILS 1507 Query: 1776 XXXIDNESVYITWFP-SEKNGGSPIIDYKVE----------------IKQEGKKW----- 1813 SV I W P +E ++ +++ I G W Sbjct: 1508 VTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTS 1567 Query: 1814 ----KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQP 1869 + + L+ + Y+ R+ N +G P + ++ +G+ + P + P Sbjct: 1568 MYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEG-PSSPPQEVFVGEAV-PTAAP 1625 Query: 1870 RNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEF-KTVKGKSWTKIVTVGGSVHEHC 1926 RN VV +T+ + + W P +S G I Y I F + +G ++ T+ + + Sbjct: 1626 RNVVVHGATATQLDVTWEPPPLDSQNGD-IQGYKIYFWEAQRGNLTERVKTLFLAENSVK 1684 Query: 1927 IENIKEKDEIIFRISAENTVG---VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 ++N+ + ++A N G S PT+ Q+ PS P++ ++ + + V Sbjct: 1685 LKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQT-----QQAAPSAPSS-VKFSELTTTSV 1738 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM-EVGKVDV---NTLKFNIRDLSENHTYMI 2039 SW P++ G L GY + + + ++ VDV + L ++DL+E TY Sbjct: 1739 NVSWEAPQFPNGI-LEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRF 1797 Query: 2040 RIYAR 2044 RI A+ Sbjct: 1798 RIRAK 1802 Score = 81.8 bits (193), Expect = 2e-13 Identities = 98/459 (21%), Positives = 189/459 (41%), Gaps = 36/459 (7%) Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC--ILRDESCTAEVTVVE 1104 ++W++DG ++ + H R+L I N + D G Y C +LR S + V Sbjct: 247 IIWKKDGVLLSGGISD-------HNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAY 299 Query: 1105 L----PPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGS--EIQFSNHIQLTI 1156 L PP+ + + + K KG + W+KD + E++ + Sbjct: 300 LSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 359 Query: 1157 DGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 DG L+I DD G + C G + + L V + N T R P V Sbjct: 360 DGG---LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNIT-RGPLDSTVIDGM 415 Query: 1213 DAYLTVEIPDETLD-VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 L E +TW K + ++ + + + ++ +L+I D YTC+ Sbjct: 416 SVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLA 475 Query: 1271 LDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDE--WIVNSKI 1327 +++ + ++V + +I ++ + +G+ +++ P+ W + Sbjct: 476 TNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGAT 535 Query: 1328 IKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP 1387 + H + +D ++ SL I + + D G Y R+ + G+ ++ + P P P Sbjct: 536 LGTESHPRIRLD-RNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHP 594 Query: 1388 --NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNL 1443 + ++ +IN+ W +P + GNS +I Y++E E + + + ++ TS+ + L Sbjct: 595 VATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGL 653 Query: 1444 KTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 SY+FR AVN+V S+ TE + +E P Sbjct: 654 VPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 692 Score = 78.2 bits (184), Expect = 2e-12 Identities = 115/497 (23%), Positives = 204/497 (41%), Gaps = 47/497 (9%) Query: 635 TFSKKPKAQYVDEGSDILLEC-RLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 +F + K Q V G ++ R+ + P+P + W G +I P ++ +E+ + + + Sbjct: 114 SFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSR-AITLENTLVILST 172 Query: 694 VLKITNVKKFQEGTYTVVAV---NREGEASLPIVLKIKT-GEKEP--PQVIEPLKSMIVR 747 V G Y V AV N + + S PI L ++ G +P P +I P K+ V Sbjct: 173 VAP-------DAGRYYVQAVNDKNGDNKTSQPITLTVEVGGPADPIAPTIIIPPKNTSVV 225 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD-THSITILKPKKVKDEGVYTLK 806 G S + + + V N RP I K L + D +TI P D G Y Sbjct: 226 AGTSEV-TLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTG-SDAGYY--- 280 Query: 807 AENSEGIAETSAVITVEEPTEENA-EPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSI 864 E + +S+V +V + EPP F+ + IT + + + + + P PSI Sbjct: 281 --ECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSI 338 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 TWY++ ++ E +T+ + L I+ + + D+G ++C A N+AG+ + + Sbjct: 339 TWYKDAAVVE-VEKLTRFRQRNDGGLQISGLVPD-DTGMFQCFARNAAGEVQTSTYLAVT 396 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEI-SGMDHREIIQEGRX 981 + S +G +V+L C+TS + W ++ + SG Sbjct: 397 SIAPNITRGPLDS-TVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLES 455 Query: 982 XXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037 D G C+ + E S LVV + QD V + A + Sbjct: 456 GSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR-TRITKPPQDQSVIKGTQASMV 514 Query: 1038 VEINSE---TADVVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCIL-- 1091 + + T +WE+DG + + + + ++ G L+I T D G Y+C + Sbjct: 515 CGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG---SLHISQTWSGDIGTYTCRVIS 571 Query: 1092 --RDESCTAEVTVVELP 1106 ++S +A + V +LP Sbjct: 572 AGGNDSRSAHLRVRQLP 588 Score = 77.8 bits (183), Expect = 3e-12 Identities = 77/298 (25%), Positives = 128/298 (42%), Gaps = 25/298 (8%) Query: 633 PPTFSKKPKAQYVDEGSDIL-LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F K+P+ E ++ + C+ +P P I W +K +V E ++ + + Sbjct: 305 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITW-YKDAAVVEVEKLTRFRQRND--- 360 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I+ + G + A N GE L + + P PL S ++ G S Sbjct: 361 -GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTS--IAPNITRGPLDSTVI-DGMS 416 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKA----LPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V+L+ + G PRP ITW K + + + LP + ++ S+ ++ P + D G YT A Sbjct: 417 VVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL-LISPTHISDAGTYTCLA 475 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI--T 865 NS G+ E SA + V T +PP Q+ +V + +V VT +P +I Sbjct: 476 TNSRGVDEASADLVVWART-RITKPP------QDQSVIKGTQASMVCGVTHDPRVTIRYI 528 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W ++ + D N L I+ S D G Y C ++ G S A + + Sbjct: 529 WEKDGATLGTESHPRIRLD-RNGSLHISQTWSG-DIGTYTCRVISAGGNDSRSAHLRV 584 Score = 67.7 bits (158), Expect = 3e-09 Identities = 91/414 (21%), Positives = 157/414 (37%), Gaps = 19/414 (4%) Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G S ++ ++ P G + EI S+ + W+ P + G+ LT Y I E + Sbjct: 878 GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGI-LTGYRISWEEYNRT 936 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 + Y + L Y V A G + + + I ++P Sbjct: 937 NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQ-VSASTISSGVPPELPGPPT 995 Query: 1772 XXXXXXXIDNESVYITWFPSEKNGGSP---IIDYKVEIKQEGKKW----KXXXXXXXXXA 1824 I SV + + P S +++ +V + EG++W + Sbjct: 996 NLGISN-IGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSM 1054 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 + L+ T Y FR+ N +GTS P KI + P P N + ++ S+ L Sbjct: 1055 EVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQA-PPDMAPANVSLRTASETSLWL 1113 Query: 1885 KW---TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV-HEHCIENIKEKDEIIFRI 1940 +W E E NG Y I++ G T V V ++ IE+++E E ++ Sbjct: 1114 RWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQV 1173 Query: 1941 SAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLL 1999 A N +G S P SQ+V +VPS + S+ ++ W PE D +L Sbjct: 1174 QAFNAIG-SGPW-SQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVL 1231 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLK-FNIRDLSENHTYMIRIYARNEIGLSEP 2052 GY + ++ V+ N+ + + L + Y +++ A IG P Sbjct: 1232 GYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP 1285 Score = 60.9 bits (141), Expect = 4e-07 Identities = 33/120 (27%), Positives = 65/120 (54%), Gaps = 6/120 (5%) Query: 1379 DKPSPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITK 1435 D+P PP +P + + D + S+ + W EP + G S + YY ++ +E+ + W + +++ Sbjct: 1396 DRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSASVSH 1454 Query: 1436 TQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 +S + LK +SY+FR A N++ S+ SE +E ++ ++PT+ + TT Sbjct: 1455 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1514 Score = 60.1 bits (139), Expect = 7e-07 Identities = 86/392 (21%), Positives = 146/392 (37%), Gaps = 24/392 (6%) Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GPVIMREISR--ESVTIEWK 1688 I++L+ + ++A N G+ T+ + S P GP + ++ S+ + W Sbjct: 1160 IEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 1219 Query: 1689 --PPLDDGGLELTKYAIEKHEPDNNR---WIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 P D GL L + K + + + W+ + R + + L + Y +V+A Sbjct: 1220 EVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQ---LTGLGKYVLYEVQVLA 1276 Query: 1744 QNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYK 1803 +G + S P +++ LD + SV + W P G I+ Y+ Sbjct: 1277 FTRIG--DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI-ILAYQ 1333 Query: 1804 VEIKQEGKKWKXXXXXXXXXARIQK----LSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 + + + Q L + Y FRI A+ G +T Sbjct: 1334 ITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWG-EAAEALVVTT 1392 Query: 1860 GKTLTPPSQPRNFVVSEST-SRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT-KIVT 1917 K P R V E +RSV L W EP S+G SP+ Y I+ + + W + Sbjct: 1393 EKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSPVRYYTIQTRELPSGRWALHSAS 1451 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM 1977 V + ++ +K FR+ A N +G S +E A PT L + Sbjct: 1452 VSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTP 1510 Query: 1978 VGSNIVMTSWGTPEWDG-GAPLLGYNIAIRDV 2008 + V+ W P D LLG+ I R++ Sbjct: 1511 HTTTSVLIRWQPPAEDKINGILLGFRIRYREL 1542 Score = 53.6 bits (123), Expect = 6e-05 Identities = 26/74 (35%), Positives = 40/74 (54%), Gaps = 2/74 (2%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V CQ +G P P ITW++ A+++ + + +D L I + P+D G F C A+ Sbjct: 324 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--GLQISGLVPDDTGMFQCFAR 381 Query: 587 NAAGFASSTTELIV 600 NAAG ++T L V Sbjct: 382 NAAGEVQTSTYLAV 395 Score = 52.0 bits (119), Expect = 2e-04 Identities = 26/80 (32%), Positives = 40/80 (50%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 DG +V C+ G PRP ITW + I+ + +L+I DAGT+T Sbjct: 413 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 472 Query: 583 CVAKNAAGFASSTTELIVEA 602 C+A N+ G ++ +L+V A Sbjct: 473 CLATNSRGVDEASADLVVWA 492 Score = 50.8 bits (116), Expect = 4e-04 Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 16/199 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 I P ++ P V +G ++L C P P I W KGE I+ ++ + + + Sbjct: 398 IAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESG 456 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 ++ T++ GTYT +A N G EAS +V+ +T +PPQ V +G Sbjct: 457 SLLISPTHIS--DAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ------DQSVIKG 508 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTL 805 + V +PR TI + K L T+S D + + D G YT Sbjct: 509 TQASMVCGVTHDPRVTIRYIW-EKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTC 567 Query: 806 KAENSEGIAETSAVITVEE 824 + ++ G SA + V + Sbjct: 568 RVISAGGNDSRSAHLRVRQ 586 Score = 49.2 bits (112), Expect = 0.001 Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 9/126 (7%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV---YDKPSKPEGPVIMREISRESVTIE 1686 +++K+L + ++ I A +E + P P P+I+R S ++ I Sbjct: 1784 LKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSS--AIAIH 1841 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQK--LNENCEYMFRVIA 1743 W D G +T+Y IE D W I + D+ ++V +Y L Y FRVIA Sbjct: 1842 WSSG-DPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIA 1900 Query: 1744 QNPVGF 1749 N GF Sbjct: 1901 VNDYGF 1906 Score = 48.8 bits (111), Expect = 0.002 Identities = 44/144 (30%), Positives = 67/144 (46%), Gaps = 13/144 (9%) Query: 1337 SIDSKSASLTIKKVENTDAGI---YKLRLENNCGHADVEMNVTI---LDKPSPPGKPNIL 1390 ++D K S KV++ G+ +++R + ++E NVT P PPG P I+ Sbjct: 1773 TVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIV 1832 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTS----IQNLKT 1445 SS+I I W + G I YV+E + D W I +K+I K +S + LK Sbjct: 1833 RY-SSAIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1890 Query: 1446 NSSYRFRAYAVNEVDISDASETTE 1469 SY FR AVN+ S ++ Sbjct: 1891 GVSYDFRVIAVNDYGFGTPSSPSQ 1914 >UniRef50_Q7Q3K8 Cluster: ENSANGP00000009916; n=4; Endopterygota|Rep: ENSANGP00000009916 - Anopheles gambiae str. PEST Length = 1448 Score = 106 bits (254), Expect = 8e-21 Identities = 119/494 (24%), Positives = 211/494 (42%), Gaps = 50/494 (10%) Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 D IL + + + T +++W +D + P F +R IR+ D G+Y+CI Sbjct: 270 DSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRH---EDIGDYTCI 326 Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141 R+ S TA V V+ +PP T+L+ +KV + T E + G+ VRWF+ Sbjct: 327 ARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKV----QFTCEAKAMPGNVTVRWFR 382 Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS 1195 +GS ++ ++ + +K L I DD+G+Y+CEV N +A L +E P+ Sbjct: 383 EGSPVREVAALETRVTIRKDGSLIINPVSADDSGQYTCEVSNGIGEPQSASAYLNIEYPA 442 Query: 1196 -INFTLRLPEF-ILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 + FT + + Y+ P + VTW K K ++E + ++ + +L Sbjct: 443 KVTFTPTIQYLPFRLAGVVQCYIKANPPLQY--VTWTKDKRLLEPYQTKDIVI-MNNGSL 499 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 + + ++ Q YTC +A+ T ++V V + P V+ + Y+ K G V + Sbjct: 500 LFTRVNQNHQGRYTCTPYNAQGTQGSSGHMEVLVRKPPAFTVEPDPLYQRKVGESVEMHC 559 Query: 1310 DYQ---AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNC 1366 D Q +PN +W + + + + I+ S ++TI+ + +D G Y+ N Sbjct: 560 DAQEAEGTSKPNIQW--QRRDGQPLQKNRVRIN--SGNITIENLRRSDFGYYQCVASNEV 615 Query: 1367 GHADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425 V +++ P N+ S+ + W + G Y + Y+E + Sbjct: 616 A-TIVSATQLVIEGTQPHAPYNLSGSATEFSVTLSWMPGYSGGPDYKQDYTIWYREAGVS 674 Query: 1426 EW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT 1483 EW I V TQ +I L ++Y F+ N + S KVI + + Sbjct: 675 EWSTIPVTPSGSTQVTINRLSPGTTYEFQVIGKNALGDGMMS------KVITIRTLDAQK 728 Query: 1484 VEKPLKNITTEPNE 1497 +KP T PN+ Sbjct: 729 AKKP-STTTAAPND 741 Score = 89.0 bits (211), Expect = 1e-15 Identities = 77/333 (23%), Positives = 134/333 (40%), Gaps = 25/333 (7%) Query: 633 PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP FS P+ YV+ G I+L C+ P P+I W + P + + + Sbjct: 253 PPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDG----- 307 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I+ ++ G YT +A N EG+ S + I G ++ P + +GE Sbjct: 308 -TELRISTIRHEDIGDYTCIARNGEGQVSHTARVIIAGG----AVIMVPPTNQTKLEGEK 362 Query: 752 VILSAQVVGNP-RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V + + P T+ W + PV+ AL T+ I+ P D G YT + Sbjct: 363 VQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKDGSLIINPVSADDSGQYTCEV 422 Query: 808 ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G ++ SA + +E P + P + Q + + G ++ + P+ +TW Sbjct: 423 SNGIGEPQSASAYLNIEYPAKVTFTPTI-----QYLPFRLAGVVQCYIK-ANPPLQYVTW 476 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ ++ P +T N L+ T V+ G Y C N+ G + + V Sbjct: 477 TKDKRLLEPYQT-KDIVIMNNGSLLFTRVNQN-HQGRYTCTPYNAQGTQGSSGHMEVLVR 534 Query: 927 K-VTFVKHLQKSYETEEGKTVILECQTSHTVST 958 K F Y+ + G++V + C T Sbjct: 535 KPPAFTVEPDPLYQRKVGESVEMHCDAQEAEGT 567 Score = 60.5 bits (140), Expect = 5e-07 Identities = 70/252 (27%), Positives = 109/252 (43%), Gaps = 24/252 (9%) Query: 695 LKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L +T++++ +G Y VV +NR + P + P + V G+S+ Sbjct: 213 LNLTDIRESDQGWYECKVVFLNRPPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSI 272 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE--GVYTLKAENS 810 IL+ Q G P P I W K+ PV P+ + G + T L+ ++ E G YT A N Sbjct: 273 ILNCQADGTPTPEILWYKDANPVD--PSSTVGIFNDGTELRISTIRHEDIGDYTCIARNG 330 Query: 811 EG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 EG ++ T+ VI PP + + EK A+ V ++ W+R Sbjct: 331 EGQVSHTARVIIAGGAV--IMVPPTNQTKLE----GEKVQFTCEAKAMPGNV-TVRWFRE 383 Query: 870 ----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK-SSHGARVTID 924 E+ + +T DG L+I V ++ DSG Y C SN G+ S A + I+ Sbjct: 384 GSPVREVAALETRVTIRKDG---SLIINPVSAD-DSGQYTCEVSNGIGEPQSASAYLNIE 439 Query: 925 V-EKVTFVKHLQ 935 KVTF +Q Sbjct: 440 YPAKVTFTPTIQ 451 Score = 60.1 bits (139), Expect = 7e-07 Identities = 94/409 (22%), Positives = 153/409 (37%), Gaps = 58/409 (14%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ CQ +G P P+I W++ + PS ++ D + IR ED G +TC Sbjct: 269 GDSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRH---EDIGDYTC 325 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A+N G S T +I+ G + + +PPT K Sbjct: 326 IARNGEGQVSHTARVIIA------GGAVIM------------------VPPTNQTKL--- 358 Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEI--VPDENISVAIESDMHMYCSVLKITNV 700 EG + C A+P + W +G + V V I D L I V Sbjct: 359 ---EGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKD-----GSLIINPV 410 Query: 701 KKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 G YT N GE S L I+ K P + + V+ Sbjct: 411 SADDSGQYTCEVSNGIGEPQSASAYLNIEYPAK---VTFTPTIQYLPFRLAGVVQCYIKA 467 Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSA 818 P +TW K+ + ++ TK ++ ++L + +G YT N++G +S Sbjct: 468 NPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNHQGRYTCTPYNAQGTQGSSG 527 Query: 819 --VITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 + V +P EP PL+ + E +V+ + ++ P+I W R + P Sbjct: 528 HMEVLVRKPPAFTVEPDPLYQRKVGE-SVEMHCDAQEAEGTSK---PNIQWQRRDG--QP 581 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + + NI I N+ D G Y+CVASN ++ I+ Sbjct: 582 LQKNRVRINSGNI--TIENL-RRSDFGYYQCVASNEVATIVSATQLVIE 627 Score = 58.4 bits (135), Expect = 2e-06 Identities = 64/264 (24%), Positives = 105/264 (39%), Gaps = 20/264 (7%) Query: 1509 PQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--C 1563 P VTW +D + L+ T N Y C +N G +S Sbjct: 470 PLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNHQGRYTCTPYNAQGTQGSSGHM 529 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLV---TAVIEGIPPPEVIWYK-NGNKLENDKEY 1619 V +++ P T+ + + Q+ KVG+ + EG P + W + +G L+ ++ Sbjct: 530 EVLVRKPPAFTVEPDPLYQR-KVGESVEMHCDAQEAEGTSKPNIQWQRRDGQPLQKNR-- 586 Query: 1620 NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 + + I I+ L+RS Y ASN T V T V + ++P P + + Sbjct: 587 ---VRINSGNITIENLRRSDFGYYQCVASNEVATI-VSATQLVIEG-TQPHAPYNLSGSA 641 Query: 1680 RE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 E SVT+ W P G Y I E + W + I +L+ Y Sbjct: 642 TEFSVTLSWMPGYSGGPDYKQDYTIWYREAGVSEWSTIPVTPSGSTQVTINRLSPGTTYE 701 Query: 1739 FRVIAQNPVGFSEALESEPIVIKT 1762 F+VI +N +G + + S+ I I+T Sbjct: 702 FQVIGKNALG--DGMMSKVITIRT 723 Score = 47.6 bits (108), Expect = 0.004 Identities = 38/161 (23%), Positives = 64/161 (39%), Gaps = 8/161 (4%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT--YENRXXXXXXXXXXXXXXXYKCIAFN 1554 + I L C G P P++ WY+D + + + + Y CIA N Sbjct: 270 DSIILNCQADGTPTPEILWYKDANPVDPSSTVGIFNDGTELRISTIRHEDIGDYTCIARN 329 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI-WYKNGNKL 1613 G+V + V I VI + Q G++ T + +P + W++ G+ + Sbjct: 330 GEGQVSHTARVIIAGGAVIMV--PPTNQTKLEGEKVQFTCEAKAMPGNVTVRWFREGSPV 387 Query: 1614 EN--DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 E +T ++ S+I I + S +YT E SN G Sbjct: 388 REVAALETRVTIRKDGSLI-INPVSADDSGQYTCEVSNGIG 427 Score = 40.7 bits (91), Expect = 0.43 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 1567 IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 + P +++ EDI + +GD ++ +G P PE++WYK+ N + D + Sbjct: 250 VHAPPRFSVTPEDIIYVN-LGDSIILNCQADGTPTPEILWYKDANPV--DPSSTVGIFND 306 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + +RI ++ YT A N G S Sbjct: 307 GTELRISTIRHEDIGDYTCIARNGEGQVS 335 Score = 40.3 bits (90), Expect = 0.57 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G VQF C+ + P + WFR+ + ++ + +L+I V +D+G + Sbjct: 359 EGEKVQFTCEAKAMPGNVTVRWFREGSPVREVAALETRVTIRKDGSLIINPVSADDSGQY 418 Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603 TC N G S++ L +E P Sbjct: 419 TCEVSNGIGEPQSASAYLNIEYP 441 >UniRef50_Q98SW3 Cluster: Transmembrane receptor Roundabout3; n=23; Euteleostomi|Rep: Transmembrane receptor Roundabout3 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1419 Score = 105 bits (252), Expect = 1e-20 Identities = 98/372 (26%), Positives = 159/372 (42%), Gaps = 28/372 (7%) Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664 SD G + V A+++ P F ++P Q V + +C + P P Sbjct: 228 SDAGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLADDTVDFQCEVQGDPAPT 287 Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 I W K E +P + ++ L++T VK EG+YT ++ N G+A Sbjct: 288 IRWK-KEEGELPRGRFEIRADNS-------LRLTQVKAEDEGSYTCLSENSVGKAEASGS 339 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK--S 782 L++ PPQ++ + I QG +V GNP P + W K V P++ S Sbjct: 340 LQVHV----PPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPS 395 Query: 783 DGDTHSITI-----LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 S+++ + +D G Y +A + G T A++ VE T + PP+ Sbjct: 396 QSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVES-TPSDRIPPIIRQ 454 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIELVITNVD 896 T+ T +L V NP+PSI W R+ + I+ E I+ EN L IT + Sbjct: 455 GPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLM---ENGTLQITAL- 510 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSH 954 E DSG Y CVAS+ +G++S +T+ + + Y+ K V+ + T + Sbjct: 511 QETDSGAYTCVASSLSGETSWSGVLTVKESGGLSASPVSEPYQLPGPPQKPVVTDV-TRN 569 Query: 955 TVSTKWYHNKKE 966 +V+ W N E Sbjct: 570 SVTLTWQPNAHE 581 Score = 82.6 bits (195), Expect = 1e-13 Identities = 112/485 (23%), Positives = 181/485 (37%), Gaps = 44/485 (9%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD----ENISVAI 684 LE P + P V +G L C+ P P + W GE + D + + + Sbjct: 58 LEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLL 117 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKS 743 S + ++ K EG Y VA N GEA S L++ + Q P Sbjct: 118 PSGSLFFLRIVHGRRSKP-DEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQT--P-SD 173 Query: 744 MIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802 ++V GE ++ G+P PTI+W +NN V + + I +K D G+ Sbjct: 174 VVVAAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDERITIRGGKLMISNTRK-SDAGM 232 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y N G ++ V E P+F+ R V T+ V +P P Sbjct: 233 YVCVGTNMVGEKDSDPAELVV------FERPMFVRRPVNQVVLADDTVDFQCEVQGDPAP 286 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +I W + E P D L +T V +E D G Y C++ NS GK+ + Sbjct: 287 TIRW-KKEEGELPRGRFEIRADN---SLRLTQVKAE-DEGSYTCLSENSVGKAEASGSLQ 341 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGR 980 + V V+ + + +G+TV C T + + W ++ + Q GR Sbjct: 342 VHVPPQIVVR--PRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGR 399 Query: 981 XXXXXXXXXXXXDV-----GVIKC----IVKDQETSTMLVVKET----IPEFIRK-LQDF 1026 DV G C + T +L V+ T IP IR+ + Sbjct: 400 FSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQ 459 Query: 1027 EVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 + A L+ + + + WERDG+ I + + G ++ ++ T D G Sbjct: 460 TLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQET---DSG 516 Query: 1086 EYSCI 1090 Y+C+ Sbjct: 517 AYTCV 521 Score = 79.0 bits (186), Expect = 1e-12 Identities = 89/365 (24%), Positives = 155/365 (42%), Gaps = 48/365 (13%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+FV + + TV F+C+V+G P P I W ++ + P F++ D+ +L Sbjct: 257 PMFVRRPVNQVVLADDTVDFQCEVQGDPAPTIRWKKEEGEL-PRGRFEIRADN----SLR 311 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 + +V ED G++TC+++N+ G A ++ L V P ++ V L Sbjct: 312 LTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVP-----PQIVVRPRDQISAQGRTVTFL 366 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 G + P + EGS +L LF + SV++ + Sbjct: 367 CGTKG--NPPPAVFWQKEGSQVL---------------LFPSQPPSQSGRFSVSLSGE-- 407 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEPLKSMIVR 747 L IT+V G Y A++ G +L++++ ++ PP + + + + Sbjct: 408 -----LTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLA 462 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSITILKPKKVKDEGVYT 804 G + L V+GNP P+I W ++ + + + + + T IT L+ D G YT Sbjct: 463 PGTTAQLQCHVMGNPLPSIQWERDGQRILGIDERISLMENGTLQITALQE---TDSGAYT 519 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A + G S V+TV+E +A P +Q +K +V VTRN V ++ Sbjct: 520 CVASSLSGETSWSGVLTVKESGGLSASP--VSEPYQLPGPPQK---PVVTDVTRNSV-TL 573 Query: 865 TWYRN 869 TW N Sbjct: 574 TWQPN 578 Score = 73.7 bits (173), Expect = 5e-11 Identities = 169/845 (20%), Positives = 312/845 (36%), Gaps = 86/845 (10%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASL 1345 P+IV++ + + +G TL + P P EW + + ++ + S + S SL Sbjct: 63 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLPSGSL 122 Query: 1346 TIKKV-----ENTDAGIYKLRLENNCGHA---DVEMNVTIL-DKPSPPGKPNILEIDSSS 1396 ++ D G+Y N G A + + V IL D ++ + Sbjct: 123 FFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVVAAGEPA 182 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 + C P TI + + D E I+++ + I N + + + + Sbjct: 183 VMEC-IPPRGHPEPTISWKRNNVKVNDKDERITIRG---GKLMISNTRKSDAGMYVCVGT 238 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N V D S+ E V+ E + V +P+ + ++ ++ C G P P + W Sbjct: 239 NMVGEKD-SDPAEL--VVFERPM---FVRRPVNQVVL-ADDTVDFQCEVQGDPAPTIRWK 291 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 ++ +L + Y C++ N G+ E S + + P I + Sbjct: 292 KEEGELPRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQIVVR 351 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-----ENDKEYNITTKEKTSVIR 1631 D Q G +G PPP V W K G+++ + + + + + Sbjct: 352 PRD--QISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGELT 409 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPL 1691 I ++ S Y +A + AG+ + L+V PS P+I + + +++ L Sbjct: 410 ITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPGTTAQL 469 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE--TYCIQKLNENCEYMFRVIAQN---- 1745 + +I+ E D R + + + +E T I L E + +A + Sbjct: 470 QCHVMGNPLPSIQ-WERDGQRILGIDERISLMENGTLQITALQETDSGAYTCVASSLSGE 528 Query: 1746 -------PVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSP 1798 V S L + P+ L P + SV +TW P+ GG+ Sbjct: 529 TSWSGVLTVKESGGLSASPVSEPYQLPGPP---QKPVVTDVTRNSVTLTWQPNAHEGGAA 585 Query: 1799 IIDYKVEI--KQEGKKWKXXXXXXXXXAR-IQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 + Y +E + G W+ + LS NT Y F + A N G S P + Sbjct: 586 VTSYIIEAFSQSAGSTWQTVADFVKLEKHTVTGLSPNTIYLFIVRAVNAYGLSDPSPISE 645 Query: 1856 KITIGKTLTPPSQ--PRNFVVSE-------------STSRSVTLKWTEPESNGGSPITNY 1900 + + ++P Q V E T+ SV + W + I Y Sbjct: 646 PVRT-QDVSPTGQGVDHRQVQRELGEMSVQLHEPVLLTASSVKISWNVDRQS--QYIQGY 702 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 + ++ V G SW++ G + I N+ + E +I L + SQ++R Sbjct: 703 RLLYRPV-GGSWSQQEVKGATERSAVIANLLKGTEYEIKIRPYFNEFQGLDSRSQTLRTP 761 Query: 1961 KHATVPS-PPTA--PLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNI-AIRDVTKTMWME 2015 + VPS PP A +++ S+ + SW P D + Y + + + ++T + Sbjct: 762 EE--VPSAPPRAVNVATVKLSNSSSISVSWQPPPTDMQNGVIQEYKVWCLGNDSQTRYNI 819 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL---SEP------LESDEPFKVIPGEG 2066 VD + L ++ L Y + + A G+ S+P L +++P + G G Sbjct: 820 NQTVDGSVLSTVLKGLLPGVLYQVEVAAVTSAGVGKHSQPVSVLIKLPAEQP--TVTGGG 877 Query: 2067 SHADE 2071 S ++E Sbjct: 878 SESEE 882 Score = 66.9 bits (156), Expect = 6e-09 Identities = 117/535 (21%), Positives = 202/535 (37%), Gaps = 54/535 (10%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA--------LPTKS 782 E P+++E +IV +GE L+ + G P P + W K+ + V+ Sbjct: 59 EDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLLP 118 Query: 783 DGDTHSITILKPKKVK-DEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQ 840 G + I+ ++ K DEGVY A N G A +A + V ++ + P + Sbjct: 119 SGSLFFLRIVHGRRSKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDV---- 174 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 + E ++ + +P P+I+W RNN ++ + + +L+I+N + D Sbjct: 175 VVAAGEPAVMECIP-PRGHPEPTISWKRNNVKVNDKD---ERITIRGGKLMISNT-RKSD 229 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVST 958 +G Y CV +N G+ + E+ FV+ + TV +C Q + Sbjct: 230 AGMYVCVGTNMVGEKDSDPAELVVFERPMFVRRPVNQVVLAD-DTVDFQCEVQGDPAPTI 288 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI----VKDQETSTMLVVKE 1014 +W KKE G R + D G C+ V E S L V Sbjct: 289 RW---KKE-EGELPRGRFEIRADNSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHV 344 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGE--IIKPKKNKYDFEKRGHIR 1072 +R + + V L + V W+++G ++ P + + Sbjct: 345 PPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSL 404 Query: 1073 KLYIRNTSVH--DEGEYSC--------ILRDESCTAEVTVVE-LPPEIITRLQNQKVNKG 1121 + T VH D G Y C IL E T + +PP I NQ + G Sbjct: 405 SGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDRIPPIIRQGPANQTLAPG 464 Query: 1122 NKATFEIELTKGDAL--VRWFKDGSEI-QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 A + + G+ L ++W +DG I I L +G L+I D+G Y+C Sbjct: 465 TTAQLQCHV-MGNPLPSIQWERDGQRILGIDERISLMENG---TLQITALQETDSGAYTC 520 Query: 1179 EV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 G + + +LTV+E + E +P + ++ ++ +TW Sbjct: 521 VASSLSGETSWSGVLTVKESGGLSASPVSEPYQLPGPPQKPVVTDVTRNSVTLTW 575 Score = 64.5 bits (150), Expect = 3e-08 Identities = 69/248 (27%), Positives = 103/248 (41%), Gaps = 37/248 (14%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDF 556 E S + + P V + R + + G TV F C +G P P + W ++ ++ PSQ Sbjct: 335 EASGSLQVHVPPQIVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPP 394 Query: 557 QM--YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVX 614 + L I +V ED+G + C A + AG + L VE+ SD Sbjct: 395 SQSGRFSVSLSGELTITDVHSEDSGYYICQAISVAGSILTKALLEVESTPSDR------- 447 Query: 615 XXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 IPP + P Q + G+ L+C ++ P P I W G+ I Sbjct: 448 -----------------IPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRI 490 Query: 675 VP-DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK-TGEK 732 + DE IS+ M L+IT +++ G YT VA + GE S VL +K +G Sbjct: 491 LGIDERISL-------MENGTLQITALQETDSGAYTCVASSLSGETSWSGVLTVKESGGL 543 Query: 733 EPPQVIEP 740 V EP Sbjct: 544 SASPVSEP 551 Score = 50.0 bits (114), Expect = 7e-04 Identities = 84/374 (22%), Positives = 147/374 (39%), Gaps = 37/374 (9%) Query: 1012 VKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIK-----PKKNKYDF 1065 +++ P + D V + + A L + +V W +DGE ++ P+ ++ Sbjct: 58 LEDAAPRIVEHPSDLIVSKGEPATLNCKAEGRPTPMVEWYKDGERVETDREDPRSHRMLL 117 Query: 1066 EKRG--HIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKV 1118 +R ++ R S DEG Y C+ R+ S A + V L + + V Sbjct: 118 PSGSLFFLRIVHGRR-SKPDEGVYVCVARNYLGEAVSRNASLEVAILRDDFRQTPSDVVV 176 Query: 1119 NKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 G A E +G + + W ++ ++ + ++TI G K L I + DAG Y Sbjct: 177 AAGEPAVMECIPPRGHPEPTISWKRNNVKVNDKDE-RITIRGGK--LMISNTRKSDAGMY 233 Query: 1177 SCE----VG--NSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY 1230 C VG +S ++ E P +R P +V A+ E+ + + Sbjct: 234 VCVGTNMVGEKDSDPAELVVFERPMF---VRRPVNQVVLADDTVDFQCEVQGDPAPTIRW 290 Query: 1231 KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPK 1289 KK+ +F + +D +L + + +D+ YTC+ ++ + + V PP+ Sbjct: 291 KKEEGELPRGRFEIRAD---NSLRLTQVKAEDEGSYTCLSENSVGKAEASGSLQVHVPPQ 347 Query: 1290 IVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-----SKSAS 1344 IV R+ +G VT L + P P W + PS S S Sbjct: 348 IVVRPRDQISAQGRTVTFLCGTKGNPPPAVFWQKEGSQVLLFPSQPPSQSGRFSVSLSGE 407 Query: 1345 LTIKKVENTDAGIY 1358 LTI V + D+G Y Sbjct: 408 LTITDVHSEDSGYY 421 Score = 39.9 bits (89), Expect = 0.75 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 3/105 (2%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 + E ++ + PI + + G+T Q +C V G P P I W R I + Sbjct: 437 LLEVESTPSDRIPPIIRQGPANQTLAPGTTAQLQCHVMGNPLPSIQWERDGQRILGIDER 496 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 ++ TL I + D+G +TCVA + +G S + L V+ Sbjct: 497 ISLMEN---GTLQITALQETDSGAYTCVASSLSGETSWSGVLTVK 538 >UniRef50_UPI0000E46930 Cluster: PREDICTED: similar to sidekick-2; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to sidekick-2 - Strongylocentrotus purpuratus Length = 2931 Score = 105 bits (251), Expect = 2e-20 Identities = 144/654 (22%), Positives = 251/654 (38%), Gaps = 45/654 (6%) Query: 1379 DKPSPPGKPNI--LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKT 1436 ++P PP N+ I S S+ + + P GN+ I + V+ + W +V ++ + Sbjct: 965 ERPQPPTNLNVPGSTIQSRSVQLHFT-PGLDGNAGITLWTVQGLIGQSDRWETVFELSDS 1023 Query: 1437 QT---SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP------TVEKP 1487 I L+ + Y+FR A N S+ SE +E + ++ +P Sbjct: 1024 SARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSEQIQTDQDVPAIAPRDVRVRAFNAT 1083 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547 +T P +D E + GG ++ W G ++ + Sbjct: 1084 ALRVTWMPLDDTEWNGVPGGY---RIYWKPYGTNMQEMIFDLASPYINNHVIGGLEEWMP 1140 Query: 1548 Y--KCIAFND-HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT-----AVIEG- 1598 Y + A+N+ H + V G + V + +I+ E + T A+ + Sbjct: 1141 YDVRIEAYNEQHSGPTSGMVAGWTNEAVPSAGPSNIQALPIYYSEIMATWGDVPAIHQNG 1200 Query: 1599 -IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV- 1656 I +VI+ +NG L TT+E T I LK T+ A G + Sbjct: 1201 EILGFKVIFRENGGILMYLDVPGNTTREAT----ITHLKGYTVYTITVLAYTVVGDGVIG 1256 Query: 1657 -EVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELT-KYAIEKHEPDNNRWI 1714 EV ++ ++ P G + + SVTI W PL G++LT K N + Sbjct: 1257 NEVPVRTHEWFPGPPGGITFPTVQESSVTIAWNEPLLPNGVDLTYKVGYRLQAAPANTLV 1316 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 + +V E + + L Y F V A GF + + +VI T Sbjct: 1317 E-ENVGGSRE-HTVAGLMPEETYYFEVTASTLTGFGQ--PASALVITTTDRTAPEAPSKP 1372 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKW---KXXXXXXXXXARIQKLSI 1831 I + V ++W P NG SP+ Y ++++ + W + L+ Sbjct: 1373 TVDHIKSRQVRLSWTPG-NNGNSPLRYYIIDVRVDSGPWAQHSMTVDASQVSYIVTGLNP 1431 Query: 1832 NTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-E 1890 +T Y FR+ N+IG S + D+ T + + P P + T S+ + W P + Sbjct: 1432 HTLYYFRLKVYNDIGASPESPTSDQTTTEQDI-PEGVPTITGATPITVTSLLVTWQPPLQ 1490 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 + P+T Y +F+ + G S+ + V EH + N+ +++A N++G L Sbjct: 1491 AQTNGPLTGYSFQFRQLPGGSFMEETISDAGVTEHELLNLVRYQNYEVKLAATNSIG--L 1548 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG-GAPLLGYNI 2003 S V + VPS P + + + GS+ SW P + L GY + Sbjct: 1549 GPYSAPVYVYIGEAVPSEPPSAVTVATTGSSAFQISWVPPSTESQNGGLQGYKV 1602 Score = 94.3 bits (224), Expect = 3e-17 Identities = 170/838 (20%), Positives = 300/838 (35%), Gaps = 60/838 (7%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTL--LV 1309 L++++ ++D EYTC+ + +T ++ + ++ + + G TL +V Sbjct: 537 LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVISQKPTSVQTILGETTTLNCVV 596 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 + + P W+ + +I I +S SL I + D G+Y ++ + G Sbjct: 597 QHDSRVTPTVTWMQDGGVIIP---NGRFIIQESGSLVILSTDANDMGLYVCKVTSIAGDD 653 Query: 1370 DVEMNVTILDKP-SPPGKPNILEIDSS-SINICWDEPENTGNSTIIYYVVEYQEIDT--T 1425 N+T+L P P G D +I + W P GNS +I Y++E +E D+ T Sbjct: 654 LGSANLTVLQVPYQPQGVTATKSQDQDRTIIVSW-LPVFDGNSALIRYILEQKEDDSAFT 712 Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 E + N TQ + ++ + Y++R A N + +S+ SE + + +E PT Sbjct: 713 EVEATINPLLTQFLVTGVRPSRRYQYRLRAQNAIGMSEKSEASNVVHLPEEL----PTA- 767 Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXX 1544 P + + IF P + G KL + E N Sbjct: 768 -PPQEVDIVVTSSTSFMYIFSSPPVQFINGINQGYKLLAWEPGMESNPITELVPPNVAQS 826 Query: 1545 XXXYKCIAFNDHGEVETSCVV------GIQQKPVITISNEDIK---QKHKVGDEWLVTAV 1595 E + S + G+ PV +++ED+ + + + + Sbjct: 827 RFIGNITTLKKFTEYQASVLCYTNPGDGVPSTPVTLMTHEDVPGPVSNLGLNNVYDTSVQ 886 Query: 1596 IEGIPPPEVIWYKNGNKL---ENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + P EV +G + E+++ YN K + I L + + A Sbjct: 887 VSWEQPQEVNGALSGYSISWQEHNRTSNIYNANRKPNETSYTITALTPDTTYLIQVWAKT 946 Query: 1650 TAGTS-SVEVTLKVYDKPSKPEGPVIMR----EISRESVTIEWKPPLDDGGLELTKYAIE 1704 + G + ++ + P +P+ P + I SV + + P L DG +T + ++ Sbjct: 947 SVGPGPTTDIIISSGIPPERPQPPTNLNVPGSTIQSRSVQLHFTPGL-DGNAGITLWTVQ 1005 Query: 1705 KHEPDNNRWIKVADV-DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 ++RW V ++ D + I L Y FR+IA N G S E I+T Sbjct: 1006 GLIGQSDRWETVFELSDSSARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSE-QIQTD 1064 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXX 1822 DVP+ + ++ +TW P + + + Y++ K G + Sbjct: 1065 QDVPAIAPRDVRVRAFNATALRVTWMPLDDTEWNGVPGGYRIYWKPYGTNMQEMIFDLAS 1124 Query: 1823 ----XARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 I L Y RI A NE S P TS P + P N Sbjct: 1125 PYINNHVIGGLEEWMPYDVRIEAYNE-QHSGP-TSGMVAGWTNEAVPSAGPSNIQALPIY 1182 Query: 1879 SRSVTLKWTE-PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEII 1937 + W + P + I + + F+ G + G + E I ++K Sbjct: 1183 YSEIMATWGDVPAIHQNGEILGFKVIFRE-NGGILMYLDVPGNTTREATITHLKGYTVYT 1241 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 + A VG + VR H P PP + V + V +W P G Sbjct: 1242 ITVLAYTVVGDGVIGNEVPVR--THEWFPGPP-GGITFPTVQESSVTIAWNEPLLPNGVD 1298 Query: 1998 L---LGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 L +GY + + VG + + + L TY + A G +P Sbjct: 1299 LTYKVGYRLQAAPANTLVEENVG----GSREHTVAGLMPEETYYFEVTASTLTGFGQP 1352 Score = 82.2 bits (194), Expect = 1e-13 Identities = 92/409 (22%), Positives = 160/409 (39%), Gaps = 30/409 (7%) Query: 1669 PEG-PVIM--REISRESVTIEWKPPLD-DGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 PEG P I I+ S+ + W+PPL LT Y+ + + +++ D V Sbjct: 1464 PEGVPTITGATPITVTSLLVTWQPPLQAQTNGPLTGYSFQFRQLPGGSFMEETISDAGVT 1523 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + + L Y ++ A N +G S P+ + VPS + + Sbjct: 1524 EHELLNLVRYQNYEVKLAATNSIGLGPY--SAPVYVYIGEAVPSEPPSAVTVATTGSSAF 1581 Query: 1785 YITWFP---SEKNGGSPIIDYKVEIKQEGKKWKXXXX--------XXXXXARIQKLSINT 1833 I+W P +NGG + YKV + + A + L T Sbjct: 1582 QISWVPPSTESQNGG--LQGYKVLYWENHSRQARATIVQQTKTFPASATVATLDDLECFT 1639 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 Y + N G P + T G+ + PS+ + S+ S+ + W P S Sbjct: 1640 EYGISVKGFNAAGDG-PGSPTSYSTTGEDV--PSEVSSLQFSQVRMSSLKVSWGPPTSPC 1696 Query: 1894 GSPITNYII--EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 G+ I + + + G+ + +VT+ + + + + E++ +F + AE T P Sbjct: 1697 GTIIQYKLFYQPHEPINGERTSVVVTLPSDQYSYVAKRLGERERYLFEVHAE-TASFEGP 1755 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 Q++ P PT ++ GS+ + SW + G PL+GY I ++ + Sbjct: 1756 RRGQNITTGPQEGAPDSPTN-IDXSP-GSSFLTVSWEELVFHGDNPLIGYIIQSQEKGQD 1813 Query: 2012 MWMEVG-KVDVNTLKFNI--RDLSENHTYMIRIYARNEIGLSEPLESDE 2057 W V + N +F+I L Y R+ A +EI +SEP S+E Sbjct: 1814 TWENVNDTIGANQSQFSIPYSSLDPVTVYTFRVMAESEISVSEPAPSEE 1862 Score = 77.4 bits (182), Expect = 4e-12 Identities = 120/607 (19%), Positives = 225/607 (37%), Gaps = 39/607 (6%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX- 1539 +P + + T E L C G P P + W +DG+ + +A +R Sbjct: 477 APEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQTFGN 536 Query: 1540 -----XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y CIA N +S + + Q+ VI S + + +G+ + Sbjct: 537 LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVI--SQKPTSVQTILGETTTLNC 594 Query: 1595 VIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 V++ P V W ++G + + + I +E S++ I + Y + ++ AG Sbjct: 595 VVQHDSRVTPTVTWMQDGGVIIPNGRFII--QESGSLV-ILSTDANDMGLYVCKVTSIAG 651 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRE-SVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 L V P +P+G + ++ ++ + W P D G L +Y +E+ E D+ Sbjct: 652 DDLGSANLTVLQVPYQPQGVTATKSQDQDRTIIVSWLPVFD-GNSALIRYILEQKEDDSA 710 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 A ++ + + + + + Y +R+ AQN +G SE E+ V+ ++P+ Sbjct: 711 FTEVEATINPLLTQFLVTGVRPSRRYQYRLRAQNAIGMSEKSEASN-VVHLPEELPTAPP 769 Query: 1772 XXXXXXXIDNES-VYITWFPSEK-----NGGSPIIDYK--VEIKQEGKKWKXXXXXXXXX 1823 + S +YI P + N G ++ ++ +E + Sbjct: 770 QEVDIVVTSSTSFMYIFSSPPVQFINGINQGYKLLAWEPGMESNPITELVPPNVAQSRFI 829 Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883 I L T YQ + G +P T +T+ P N ++ SV Sbjct: 830 GNITTLKKFTEYQASVLCYTNPGDGVPST---PVTLMTHEDVPGPVSNLGLNNVYDTSVQ 886 Query: 1884 LKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 + W +P+ G+ ++ Y I ++ S + + I + + ++ A+ Sbjct: 887 VSWEQPQEVNGA-LSGYSISWQEHNRTSNIYNANRKPNETSYTITALTPDTTYLIQVWAK 945 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS---WGTPEWDGGAPLLG 2000 +VG T+ + P P P + + GS I S TP DG A + Sbjct: 946 TSVGPGPTTDI----IISSGIPPERPQPPTNLNVPGSTIQSRSVQLHFTPGLDGNAGITL 1001 Query: 2001 YNIAIRDVTKTMWMEVGKV-DVNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESD 2056 + + W V ++ D + I L Y R+ A N G +SEP E Sbjct: 1002 WTVQGLIGQSDRWETVFELSDSSARSVKITGLEPFTYYQFRMIATNVAGSSNVSEPSEQI 1061 Query: 2057 EPFKVIP 2063 + + +P Sbjct: 1062 QTDQDVP 1068 Score = 70.5 bits (165), Expect = 5e-10 Identities = 57/218 (26%), Positives = 89/218 (40%), Gaps = 7/218 (3%) Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 TY F + A G P ++ T +T P P V SR V L WT P +NG Sbjct: 1336 TYYFEVTASTLTGFGQPASALVITTTDRTA--PEAPSKPTVDHIKSRQVRLSWT-PGNNG 1392 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 SP+ YII+ + G +TV S + + + FR+ N +G S P Sbjct: 1393 NSPLRYYIIDVRVDSGPWAQHSMTVDASQVSYIVTGLNPHTLYYFRLKVYNDIGAS-PES 1451 Query: 1954 SQSVRLEKHATVP-SPPTAPLEIRMVGSNIVMTSWGTP-EWDGGAPLLGYNIAIRDVTKT 2011 S + +P PT + +++++T W P + PL GY+ R + Sbjct: 1452 PTSDQTTTEQDIPEGVPTITGATPITVTSLLVT-WQPPLQAQTNGPLTGYSFQFRQLPGG 1510 Query: 2012 MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 +ME D + + +L Y +++ A N IGL Sbjct: 1511 SFMEETISDAGVTEHELLNLVRYQNYEVKLAATNSIGL 1548 Score = 65.7 bits (153), Expect = 1e-08 Identities = 74/313 (23%), Positives = 123/313 (39%), Gaps = 25/313 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS++ C G P PQI W+R A I + + +DD +L + + D+G F C Sbjct: 360 GSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDD--GSLKLSNIEKADSGMFQC 417 Query: 584 VAKNAAGFASSTT-----ELIVEAPLSDHGS-----EMTVXXXXXXXXXXXXADILEGIP 633 A N G T E+ E L+ + + E T + I Sbjct: 418 QAINDVGEQIVDTWLQVQEIAPEITLAPNDTTILEGETTYLECAAEGAPHPTIHWEKEIA 477 Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + P + EG LEC P P I W K ++V + + + + + Sbjct: 478 PEITLSPNDTTILEGETTYLECAAEGAPHPTIHW-EKDGQLVLSASFRLNDRYVLQTFGN 536 Query: 694 VLKITNVKKFQEGTYTVVAVN--REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +L VK+ G YT +A N +S +++ +T + P ++ + GE+ Sbjct: 537 LLLQQAVKE-DSGEYTCIATNTLNTANSSASLIVYQRTVISQKPTSVQTI------LGET 589 Query: 752 VILSAQVVGNPR--PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 L+ V + R PT+TW ++ + ++ S+ IL D G+Y K + Sbjct: 590 TTLNCVVQHDSRVTPTVTWMQDGGVIIPNGRFIIQESGSLVILS-TDANDMGLYVCKVTS 648 Query: 810 SEGIAETSAVITV 822 G SA +TV Sbjct: 649 IAGDDLGSANLTV 661 Score = 60.1 bits (139), Expect = 7e-07 Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 10/140 (7%) Query: 637 SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 +K P + + E GS I L C +P P I W +I N +E D Sbjct: 347 NKSPLERIIQEAAGSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDD-----GS 401 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 LK++N++K G + A+N GE + L+++ E P + P + I+ +GE+ L Sbjct: 402 LKLSNIEKADSGMFQCQAINDVGEQIVDTWLQVQ--EIAPEITLAPNDTTIL-EGETTYL 458 Query: 755 SAQVVGNPRPTITWCKNNKP 774 G P PTI W K P Sbjct: 459 ECAAEGAPHPTIHWEKEIAP 478 Score = 58.0 bits (134), Expect = 3e-06 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 14/198 (7%) Query: 731 EKE-PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----D 785 EKE P++ + +GE+ L G P PTI W K+ + V + + + Sbjct: 473 EKEIAPEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQ 532 Query: 786 THSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 T +L+ +D G YT A N+ A +SA + V + T + +P Q I + Sbjct: 533 TFGNLLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTVISQKP----TSVQTI-LG 587 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYK 905 E T+ V + P++TW ++ +I P+ G LVI + D+ D G Y Sbjct: 588 ETTTLNCVVQHDSRVTPTVTWMQDGGVIIPNGRFIIQESG---SLVILSTDAN-DMGLYV 643 Query: 906 CVASNSAGKSSHGARVTI 923 C ++ AG A +T+ Sbjct: 644 CKVTSIAGDDLGSANLTV 661 Score = 52.0 bits (119), Expect = 2e-04 Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 7/100 (7%) Query: 505 EQSMAPIFVEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY--Y 560 E+ +AP L P T +G T EC EG P P I W + ++ S F++ Y Sbjct: 473 EKEIAPEIT--LSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQLVL-SASFRLNDRY 529 Query: 561 DDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L++++ ED+G +TC+A N A+S+ LIV Sbjct: 530 VLQTFGNLLLQQAVKEDSGEYTCIATNTLNTANSSASLIV 569 Score = 49.6 bits (113), Expect = 0.001 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 7/115 (6%) Query: 1375 VTILDKPSP--PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VK 1431 +T D+ +P P KP + I S + + W P N GNS + YY+++ + +D+ W Sbjct: 1358 ITTTDRTAPEAPSKPTVDHIKSRQVRLSW-TPGNNGNSPLRYYIIDVR-VDSGPWAQHSM 1415 Query: 1432 NITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 + +Q S + L ++ Y FR N++ S S T++ ++ PT+ Sbjct: 1416 TVDASQVSYIVTGLNPHTLYYFRLKVYNDIGASPESPTSDQTTTEQDIPEGVPTI 1470 Score = 49.2 bits (112), Expect = 0.001 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 7/129 (5%) Query: 1485 EKPLKNITTEP-NEDIELTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXX 1540 + PL+ I E I L C+ GVP P++ WYR+ + T ++ E+ Sbjct: 348 KSPLERIIQEAAGSSITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDDGSLKLSNI 407 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 ++C A ND GE + +Q+ P IT++ D G+ + EG Sbjct: 408 EKADSGMFQCQAINDVGEQIVDTWLQVQEIAPEITLAPNDTTILE--GETTYLECAAEGA 465 Query: 1600 PPPEVIWYK 1608 P P + W K Sbjct: 466 PHPTIHWEK 474 Score = 42.3 bits (95), Expect = 0.14 Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 3/115 (2%) Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGENIELVITNVDSEI 899 + T+ E T L P P+I W ++ +++ S S + + + ++ + Sbjct: 486 DTTILEGETTYLECAAEGAPHPTIHWEKDGQLVLSASFRLNDRYVLQTFGNLLLQQAVKE 545 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 DSG+Y C+A+N+ ++ A ++ V + T + S +T G+T L C H Sbjct: 546 DSGEYTCIATNTLNTANSSA--SLIVYQRTVISQKPTSVQTILGETTTLNCVVQH 598 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 7/103 (6%) Query: 1374 NVTILDKPSPPGKPNILEID--SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 N+T + P P ++ SS + + W+E G++ +I Y+++ QE W +V Sbjct: 1760 NITTGPQEGAPDSPTNIDXSPGSSFLTVSWEELVFHGDNPLIGYIIQSQEKGQDTWENVN 1819 Query: 1432 N---ITKTQTSI--QNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + ++Q SI +L + Y FR A +E+ +S+ + + E Sbjct: 1820 DTIGANQSQFSIPYSSLDPVTVYTFRVMAESEISVSEPAPSEE 1862 Score = 39.1 bits (87), Expect = 1.3 Identities = 43/198 (21%), Positives = 74/198 (37%), Gaps = 23/198 (11%) Query: 997 IKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEI 1055 ++C + T+ KE PE D + E + LE + WE+DG++ Sbjct: 458 LECAAEGAPHPTIHWEKEIAPEITLSPNDTTILEGETTYLECAAEGAPHPTIHWEKDGQL 517 Query: 1056 IKPKK----NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---------EVTV 1102 + ++Y + G+ L ++ D GEY+CI + TA + TV Sbjct: 518 VLSASFRLNDRYVLQTFGN---LLLQQAVKEDSGEYTCIATNTLNTANSSASLIVYQRTV 574 Query: 1103 VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 + P + + + + +T V W +DG I + + G Sbjct: 575 ISQKPTSVQTILGETTTLNCVVQHDSRVT---PTVTWMQDGGVIIPNGRFIIQESG---S 628 Query: 1163 LKIYDCDLDDAGEYSCEV 1180 L I D +D G Y C+V Sbjct: 629 LVILSTDANDMGLYVCKV 646 Score = 37.5 bits (83), Expect = 4.0 Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 +I L T P P I WYRN I+ + + L ++N++ + DSG ++C A Sbjct: 362 SITLPCMATGVPAPQIKWYRNAADITTMGNSRFRMEDDG-SLKLSNIE-KADSGMFQCQA 419 Query: 909 SNSAGKSSHGARVTIDVEKVTFVKHLQKSYET-EEGKTVILECQTSHTVSTKWYHNKKEI 967 N G+ + V+++ L + T EG+T LEC + H +KEI Sbjct: 420 INDVGEQI--VDTWLQVQEIAPEITLAPNDTTILEGETTYLEC-AAEGAPHPTIHWEKEI 476 Query: 968 S 968 + Sbjct: 477 A 477 >UniRef50_UPI0000DB7210 Cluster: PREDICTED: similar to Stretchin-Mlck CG18255-PA, isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar to Stretchin-Mlck CG18255-PA, isoform A - Apis mellifera Length = 2577 Score = 104 bits (250), Expect = 2e-20 Identities = 144/614 (23%), Positives = 255/614 (41%), Gaps = 67/614 (10%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 EG PP F ++ V G+ + + P I W E+I S E + Sbjct: 112 EGDPPIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEG--N 169 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK-EPPQVIEPLKSMIVRQ 748 YC + + V EG +T +A NR G +S L + + + P+ +E L++++ Sbjct: 170 FYC--VDVAPVTVEDEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPEFVEELRALLTET 227 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 G +V L +VVG P P + W K+NK +KA GD ++T G+YT +A Sbjct: 228 G-TVSLECKVVGVPTPVLRWFKDNKEIKA------GDVFALT-ANLDDPTSLGIYTCEAV 279 Query: 809 NSEGIAETSAVITV--EEPTEENAEP----------PLFINRFQEITVKEKGTIKLVARV 856 N GIA +S+ + V + E + +P P+F Q+ + T++L +V Sbjct: 280 NCMGIAYSSSKVHVVGKGSREGSLKPADSLIPFGPLPIFTKILQDECCRIGDTLRLSCQV 339 Query: 857 TRNPVP-SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-K 914 P P +ITWY I SE DG + N +D G++KCVA+N+ K Sbjct: 340 QVPPWPKAITWYNKEGRIEASEKYHVMEDGLGGYSIEVNPVEAMDEGEWKCVATNAEDMK 399 Query: 915 SSHGARVTIDV----EKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEIS 968 V + + K F++ L K+ TEEG V EC+ T +W+ + +E+ Sbjct: 400 QFTTCHVAMSIPKNYRKPRFMESL-KAVLTEEG-LVSFECKVVGFPTPLLRWFKDGQELK 457 Query: 969 GMDHREIIQE---------GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEF 1019 D ++ R + I+ + ++E +L + P F Sbjct: 458 PGDVYQLTGTNSLGSYCCIARNCMGEAKSTAELTIEDIQNQLNEEERLQLLNTNQP-PIF 516 Query: 1020 IRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 I+ L+ E + + V+++ S W RD ++ + ++ I L ++ Sbjct: 517 IKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQK 576 Query: 1079 TSVHDEGEYSCILRDE------SCTAEVTVVE--LPPEIITRLQNQKVNKGNKATFEIE- 1129 D+ E+ C+ ++ SC ++ + + P+ + L+ ++G E + Sbjct: 577 LEFVDQAEWKCVASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEG-AVNLECKV 635 Query: 1130 LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAIL 1189 + +++W+KDG E++ I I G+ C L G Y+CE N C + Sbjct: 636 IGVPQPILKWYKDGVELK-PGDIHRIISGQDG-----TCCL---GTYTCEATN--CMGTV 684 Query: 1190 TVEEPSINFTLRLP 1203 + + F +LP Sbjct: 685 SSSASLLGFEDKLP 698 Score = 93.9 bits (223), Expect = 4e-17 Identities = 153/659 (23%), Positives = 273/659 (41%), Gaps = 81/659 (12%) Query: 729 TGEKEPPQVIEPLKSMIV--RQGESVILSAQVVGNP---RPTITWCKNNKPVKA--LPTK 781 T K PP+ ++P +++ V R GE +++ ++ + + + P+ + + Sbjct: 2 TKVKGPPRWLDPDQALPVQGRVGEDIVIEPRLRWSDVFDELRFELIRGDVPIPSDRYRVQ 61 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAEN-SEGIAETSAV---ITVEEPTEENAEPPLFIN 837 G+ +T LK + D G Y L A +G + S+ ++V+E E +PP+F+ Sbjct: 62 MRGNVVQLT-LKQSQKDDTGHYALVATRVGQGFEKGSSKKIHLSVDEAISEEGDPPIFLR 120 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 R ++ VK + + + + P ITW+RN E I + +G + + V Sbjct: 121 RLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEGNFYCVDVAPVTV 180 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTIDVEKV----TFVKHLQKSYETEEGKTVILECQT- 952 E D G + C+A N G+SS +R+T+ V K FV+ L ++ TE G TV LEC+ Sbjct: 181 E-DEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPEFVEEL-RALLTETG-TVSLECKVV 237 Query: 953 -SHTVSTKWYHNKKEISGMDHREIIQ--EGRXXXXXXXXXXXXDVGV------IKCIVKD 1003 T +W+ + KEI D + + +G+ + + K Sbjct: 238 GVPTPVLRWFKDNKEIKAGDVFALTANLDDPTSLGIYTCEAVNCMGIAYSSSKVHVVGKG 297 Query: 1004 QETSTM-----LVVKETIPEFIRKLQDFEVKEKDVAIL--EVEINSETADVVW-ERDGEI 1055 ++ L+ +P F + LQD + D L +V++ + W ++G I Sbjct: 298 SREGSLKPADSLIPFGPLPIFTKILQDECCRIGDTLRLSCQVQVPPWPKAITWYNKEGRI 357 Query: 1056 IKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQN 1115 +K + G + + DEGE+ C+ + + T + I + Sbjct: 358 EASEKYHVMEDGLGGY-SIEVNPVEAMDEGEWKCVATNAEDMKQFTTCHVAMSIPKNYRK 416 Query: 1116 QKVNKGNKA--------TFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIY 1166 + + KA +FE ++ L+RWFKDG E++ + QLT L Y Sbjct: 417 PRFMESLKAVLTEEGLVSFECKVVGFPTPLLRWFKDGQELKPGDVYQLT---GTNSLGSY 473 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVE--EPSINFTLRL--------PEFIL------VPA 1210 C + +G +K TA LT+E + +N RL P FI Sbjct: 474 CCIARNC------MGEAKSTAELTIEDIQNQLNEEERLQLLNTNQPPIFIKGLRSCEARI 527 Query: 1211 NTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTC 1268 N D TV++ +WY+ + +E+ E++ + + + L ++K DQ E+ C Sbjct: 528 NEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKC 587 Query: 1269 VLLD--AKSTTK--LKVEVVEF--PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 V + +S T LK+ + + PK ++ R G+ V L PQP +W Sbjct: 588 VASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEGA-VNLECKVIGVPQPILKW 645 Score = 89.4 bits (212), Expect = 9e-16 Identities = 102/431 (23%), Positives = 178/431 (41%), Gaps = 59/431 (13%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E+ PIF+ +L G+ +F ++ P+ITW R I F ++ N Sbjct: 111 EEGDPPIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAGTRFSFVHEG-N 169 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 + + V ED G +TC+A+N G +S T+ L V P + E Sbjct: 170 FYCVDVAPVTVEDEGHWTCMAENRGGRSSCTSRLTVIVPKAYKRPE-------------- 215 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 F ++ +A + G+ + LEC++V +P P + W +EI + ++ Sbjct: 216 -----------FVEELRALLTETGT-VSLECKVVGVPTPVLRWFKDNKEIKAGDVFALTA 263 Query: 685 ESD----MHMY-CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE 739 D + +Y C + + + V +REG P I G P + Sbjct: 264 NLDDPTSLGIYTCEAVNCMGIAYSSSKVHVVGKGSREGSLK-PADSLIPFGPL--PIFTK 320 Query: 740 PLKSMIVRQGESVILSAQVVGNPRP-TITWCKNNKPVKA---LPTKSDG-DTHSITILKP 794 L+ R G+++ LS QV P P ITW ++A DG +SI + P Sbjct: 321 ILQDECCRIGDTLRLSCQVQVPPWPKAITWYNKEGRIEASEKYHVMEDGLGGYSIEV-NP 379 Query: 795 KKVKDEGVYTLKAENSEGIAE-TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 + DEG + A N+E + + T+ + + P +N P F+ + + + E+G + Sbjct: 380 VEAMDEGEWKCVATNAEDMKQFTTCHVAMSIP--KNYRKPRFMESLKAV-LTEEGLVSFE 436 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +V P P + W+++ + + P G+ +L TN G Y C+A N G Sbjct: 437 CKVVGFPTPLLRWFKDGQELKP---------GDVYQLTGTN-----SLGSYCCIARNCMG 482 Query: 914 KSSHGARVTID 924 ++ A +TI+ Sbjct: 483 EAKSTAELTIE 493 Score = 80.6 bits (190), Expect = 4e-13 Identities = 70/308 (22%), Positives = 133/308 (43%), Gaps = 24/308 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + KA +EG + EC++V P P + W G+E+ P + + + + YC Sbjct: 417 PRFMESLKAVLTEEGL-VSFECKVVGFPTPLLRWFKDGQELKPGDVYQLTGTNSLGSYCC 475 Query: 694 VLK--ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + + + K E T + E L ++ +PP I+ L+S R E Sbjct: 476 IARNCMGEAKSTAELTIEDIQNQLNEEERLQLL-----NTNQPPIFIKGLRSCEARINED 530 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT-KSDGDTHSITILKPKKVK--DEGVYTLKAE 808 + QV +P P+ +W +++ PV+ + + I L +K++ D+ + A Sbjct: 531 FRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKCVAS 590 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N G + TS + + P ++ + P F+ + I + ++G + L +V P P + WY+ Sbjct: 591 NDHGQSITSCFLKLIIP--KHYKKPKFLESLRAI-LSDEGAVNLECKVIGVPQPILKWYK 647 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 + + P + I +I+ D G Y C A+N G S A + +K+ Sbjct: 648 DGVELKPGD----------IHRIISGQDGTCCLGTYTCEATNCMGTVSSSASLLGFEDKL 697 Query: 929 TFVKHLQK 936 K +++ Sbjct: 698 PVRKEIKE 705 Score = 77.4 bits (182), Expect = 4e-12 Identities = 121/546 (22%), Positives = 222/546 (40%), Gaps = 47/546 (8%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+R+L D VK VEI S T + W R+ E I ++ F G+ + Sbjct: 116 PIFLRRLTDLAVKVGTRTRFLVEIRSSTTPKITWHRNAEQIHAG-TRFSFVHEGNFYCVD 174 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELP-----PEIITRLQNQKVNKGNKATF 1126 + +V DEG ++C+ + SCT+ +TV+ +P PE + L+ G + Sbjct: 175 VAPVTVEDEGHWTCMAENRGGRSSCTSRLTVI-VPKAYKRPEFVEELRALLTETGTVSLE 233 Query: 1127 EIELTKGDALVRWFKDGSEIQFSNHIQLTID-GKKQKLKIYDCD-LDDAG-EYSCE---- 1179 + ++RWFKD EI+ + LT + L IY C+ ++ G YS Sbjct: 234 CKVVGVPTPVLRWFKDNKEIKAGDVFALTANLDDPTSLGIYTCEAVNCMGIAYSSSKVHV 293 Query: 1180 VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--------TVEIPDETLDVTWYK 1231 VG L + I F LP F + + + V++P +TWY Sbjct: 294 VGKGSREGSLKPADSLIPFG-PLPIFTKILQDECCRIGDTLRLSCQVQVPPWPKAITWYN 352 Query: 1232 KKSVIEDTEKFTLISD-VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV--EVVEFP- 1287 K+ IE +EK+ ++ D + ++ + D+ E+ CV +A+ + + P Sbjct: 353 KEGRIEASEKYHVMEDGLGGYSIEVNPVEAMDEGEWKCVATNAEDMKQFTTCHVAMSIPK 412 Query: 1288 ----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKS 1342 P+ ++ + + G V+ FP P W + + +K + +S Sbjct: 413 NYRKPRFMESLKAVLTEEGL-VSFECKVVGFPTPLLRWFKDGQELKPGDVYQLTGTNSLG 471 Query: 1343 ASLTIKKVENTDA-GIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 + I + +A +L +E+ + E + +L+ PP L + IN + Sbjct: 472 SYCCIARNCMGEAKSTAELTIEDIQNQLNEEERLQLLNTNQPPIFIKGLRSCEARINEDF 531 Query: 1402 DEPENTGNS---TIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 S + +Y + + + ++ +N+ +Q L+ ++ A N Sbjct: 532 RFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLDVQKLEFVDQAEWKCVASN 591 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 + S T+ + K+I + P + L+ I ++ + L C GVPQP + WY+ Sbjct: 592 D---HGQSITSCFLKLIIPKHYKKPKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYK 647 Query: 1518 DGKKLK 1523 DG +LK Sbjct: 648 DGVELK 653 Score = 53.6 bits (123), Expect = 6e-05 Identities = 54/227 (23%), Positives = 90/227 (39%), Gaps = 18/227 (7%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYENRX--X 1534 Q P K L++ NED T P+P +WYRD ++ + + EN Sbjct: 512 QPPIFIKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICH 571 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI-----QQKPVITISNEDIKQKHKVGDE 1589 +KC+A NDHG+ TSC + + +KP S I + DE Sbjct: 572 LDVQKLEFVDQAEWKCVASNDHGQSITSCFLKLIIPKHYKKPKFLESLRAI-----LSDE 626 Query: 1590 WLVT--AVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 V + G+P P + WYK+G +L+ D I+ ++ T + + ++ Sbjct: 627 GAVNLECKVIGVPQPILKWYKDGVELKPGDIHRIISGQDGTCCLGTYTCEATNCMGTVSS 686 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 +++ G K +P P G + R +S ++ E L D Sbjct: 687 SASLLGFEDKLPVRKEIKEPQSPNGHELARNLSLSTIHEERTSQLYD 733 Score = 48.0 bits (109), Expect = 0.003 Identities = 37/169 (21%), Positives = 73/169 (43%), Gaps = 26/169 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 PIF++ LR +F QV P P +W+R ++ ++ +++ ++ + L Sbjct: 514 PIFIKGLRSCEARINEDFRFTVQVSISPEPSFSWYRDDTPVEENERYRVAKENLGICHLD 573 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 ++++ D + CVA N G S T ++ + H + Sbjct: 574 VQKLEFVDQAEWKCVASNDHG--QSITSCFLKLIIPKHYKK------------------- 612 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 P F + +A DEG+ + LEC+++ +P+P + W G E+ P + Sbjct: 613 ----PKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYKDGVELKPGD 656 Score = 46.8 bits (106), Expect = 0.007 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 11/90 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+E LR + +G+ V EC+V G P+P + W++ +KP ++ D L Sbjct: 613 PKFLESLRAILSDEGA-VNLECKVIGVPQPILKWYKDGVELKPGDIHRIISGQDGTCCL- 670 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELI 599 GT+TC A N G SS+ L+ Sbjct: 671 ---------GTYTCEATNCMGTVSSSASLL 691 >UniRef50_Q4S0Y7 Cluster: Chromosome 5 SCAF14773, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 5 SCAF14773, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 931 Score = 104 bits (249), Expect = 3e-20 Identities = 76/294 (25%), Positives = 125/294 (42%), Gaps = 11/294 (3%) Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732 VI + SV I+W PP + L Y I++ + W+ + + + L Sbjct: 115 VIATRETDTSVLIQWAPPKEPNNL--IGYYIDQCVKGSKDWMSANHKPHNSTKFVVSGLT 172 Query: 1733 ENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 + Y+FRV A N +G SE + ES PI +K AL PS D S+ +TW Sbjct: 173 KGETYVFRVQAINELGLSEESQESAPITVKAALTPPSAPYDISLLS-CDGHSMLLTWKKP 231 Query: 1792 EKNGGSPIIDYKVEIKQEG-KKWKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 +GGS I +Y V+ ++ G W+ +++ L+ YQF++YA N G Sbjct: 232 LLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQVYAANLAGLG 291 Query: 1849 -LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTV 1907 SDD G T+ P + ++E S+ ++W +P G P+T Y +E+ Sbjct: 292 PASKHSDDFACEGWTMPEPGPAYDLSLTEVRDHSMVVEWKKPVYTGSGPVTGYHVEYCKT 351 Query: 1908 KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG---VSLPTESQSVR 1958 WT + ++E FR+ N G VS+P++ + + Sbjct: 352 GTSEWTTATETAVHQRFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAK 405 Score = 98.3 bits (234), Expect = 2e-18 Identities = 70/305 (22%), Positives = 123/305 (40%), Gaps = 6/305 (1%) Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ 1808 F + E + +++ LD + SV I W P ++ +I Y ++ Sbjct: 90 FCLPISMETVSLQSRLDPSRLRSSKVIATRETDTSVLIQWAPPKEPNN--LIGYYIDQCV 147 Query: 1809 EGKK-WKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTP 1865 +G K W + + L+ TY FR+ A NE+G S IT+ LTP Sbjct: 148 KGSKDWMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQESAPITVKAALTP 207 Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 PS P + + S+ L W +P +GGS I Y ++ + W ++ S + Sbjct: 208 PSAPYDISLLSCDGHSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVY 267 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP-PTAPLEIRMVGSNIVM 1984 +E + E F++ A N G+ ++ + T+P P P L + V + ++ Sbjct: 268 KVEGLTEGAVYQFQVYAANLAGLGPASKHSDDFACEGWTMPEPGPAYDLSLTEVRDHSMV 327 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 W P + G P+ GY++ + W + V+ F + L E Y R+ Sbjct: 328 VEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQRFFKVTGLEEGVNYEFRVRGV 387 Query: 2045 NEIGL 2049 N+ G+ Sbjct: 388 NDAGV 392 Score = 77.4 bits (182), Expect = 4e-12 Identities = 74/350 (21%), Positives = 133/350 (38%), Gaps = 18/350 (5%) Query: 1606 WYKNGNKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 W +K N ++ ++ TK +T V R++ + S+ + E S +T+K Sbjct: 153 WMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQE--------SAPITVKAA 204 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 P + + S+ + WK PL GG + +Y ++K W +V Sbjct: 205 LTPPSAPYDISLLSCDGHSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISE 264 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS-XXXXXXXXXXIDNE 1782 Y ++ L E Y F+V A N G A + +P + + Sbjct: 265 RVYKVEGLTEGAVYQFQVYAANLAGLGPASKHSDDFACEGWTMPEPGPAYDLSLTEVRDH 324 Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXXA--RIQKLSINTTYQFRI 1839 S+ + W G P+ Y VE + G +W ++ L Y+FR+ Sbjct: 325 SMVVEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQRFFKVTGLEEGVNYEFRV 384 Query: 1840 YARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 N+ G + D +T K L SQ + V + T + L + N S Sbjct: 385 RGVNDAGVGMVSMPSDPMT-AKALA-GSQEVSCTVDKKTG-DIVLSFESCVMNQESQFI- 440 Query: 1900 YIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 + ++K + S +V G+ + +N +++D ++ +S NT GVS Sbjct: 441 WKKDYKEITDFSKGVVVKTEGNTSKLIFKNAEKEDFGVYSVSVTNTDGVS 490 Score = 69.3 bits (162), Expect = 1e-09 Identities = 48/199 (24%), Positives = 92/199 (46%), Gaps = 10/199 (5%) Query: 1866 PSQPRN--FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSV 1922 PS+ R+ + + T SV ++W P+ + Y I+ + VKG K W + Sbjct: 107 PSRLRSSKVIATRETDTSVLIQWAPPKEPNN--LIGYYID-QCVKGSKDWMSANHKPHNS 163 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG--S 1980 + + + + + +FR+ A N +G+S ++ + K A +PP+AP +I ++ Sbjct: 164 TKFVVSGLTKGETYVFRVQAINELGLSEESQESAPITVKAAL--TPPSAPYDISLLSCDG 221 Query: 1981 NIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + ++ +W P GG+ + Y + R TMW EV ++ + + L+E Y + Sbjct: 222 HSMLLTWKKPLLSGGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQ 281 Query: 2041 IYARNEIGLSEPLESDEPF 2059 +YA N GL + + F Sbjct: 282 VYAANLAGLGPASKHSDDF 300 Score = 51.2 bits (117), Expect = 3e-04 Identities = 40/184 (21%), Positives = 82/184 (44%), Gaps = 19/184 (10%) Query: 1301 RGSDVTLLVDYQAFPQPN-------DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 R +D ++L+ + +PN D+ + SK H KP S + + Sbjct: 119 RETDTSVLIQWAPPKEPNNLIGYYIDQCVKGSKDWMSANH-KPH---NSTKFVVSGLTKG 174 Query: 1354 DAGIYKLRLENNCGHADVEMN---VTILDKPSPPGKP---NILEIDSSSINICWDEPENT 1407 + +++++ N G ++ +T+ +PP P ++L D S+ + W +P + Sbjct: 175 ETYVFRVQAINELGLSEESQESAPITVKAALTPPSAPYDISLLSCDGHSMLLTWKKPLLS 234 Query: 1408 GNSTIIYYVVEYQEIDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 G S I Y V+ + TT W + + I++ ++ L + Y+F+ YA N + AS Sbjct: 235 GGSNIKEYYVDKRRSGTTMWREVHIPPISERVYKVEGLTEGAVYQFQVYAANLAGLGPAS 294 Query: 1466 ETTE 1469 + ++ Sbjct: 295 KHSD 298 Score = 47.6 bits (108), Expect = 0.004 Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 6/122 (4%) Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 IS+E + +S+ T S RL+ S A E V+ W P+ L+ Sbjct: 86 ISSEFCLPISMETVSLQSRLDPSRLRSSKVIATRET----DTSVLIQWAPPKEPNN--LI 139 Query: 2000 GYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPF 2059 GY I WM N+ KF + L++ TY+ R+ A NE+GLSE + P Sbjct: 140 GYYIDQCVKGSKDWMSANHKPHNSTKFVVSGLTKGETYVFRVQAINELGLSEESQESAPI 199 Query: 2060 KV 2061 V Sbjct: 200 TV 201 Score = 44.8 bits (101), Expect = 0.026 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 + +P P ++ E+ S+ + W +P TG+ + Y VEY + T+EW + Q Sbjct: 307 MPEPGPAYDLSLTEVRDHSMVVEWKKPVYTGSGPVTGYHVEYCKTGTSEWTTATETAVHQ 366 Query: 1438 T--SIQNLKTNSSYRFRAYAVNEVDISDASETTE--YYKVIKETKIQSPTVEKPLKNI 1491 + L+ +Y FR VN+ + S ++ K + ++ S TV+K +I Sbjct: 367 RFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAKALAGSQEVSCTVDKKTGDI 424 Score = 43.2 bits (97), Expect = 0.081 Identities = 52/253 (20%), Positives = 109/253 (43%), Gaps = 29/253 (11%) Query: 681 SVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASL-----PIVLKIKTGEKEPP 735 + A E+ +H K+T +++ + V VN G + P+ K G +E Sbjct: 357 TTATETAVHQ--RFFKVTGLEEGVNYEFRVRGVNDAGVGMVSMPSDPMTAKALAGSQEVS 414 Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITI 791 ++ IV ES ++ N W K+ K + K + K++G+T + I Sbjct: 415 CTVDKKTGDIVLSFESCVM------NQESQFIWKKDYKEITDFSKGVVVKTEGNTSKL-I 467 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA------EPPLFINRFQEITVK 845 K + +D GVY++ N++G++ + + + EE T+ A P + + + Sbjct: 468 FKNAEKEDFGVYSVSVTNTDGVSSSYGIYS-EEMTKMLALSYDIRHPIIPLKAELAYKIL 526 Query: 846 EKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGEN--IELVITNVDSEIDSG 902 E+G ++ + +P + ++ NN+ +S ++ D IE ++ + E + G Sbjct: 527 ERGRVRFWLQAEEISPNVTYKFFANNKELSGADPNKMGHDVSTGIIEFILDHFTEE-NEG 585 Query: 903 DYKCVASNSAGKS 915 + C ++ GK+ Sbjct: 586 TFTCQITDGGGKA 598 Score = 40.3 bits (90), Expect = 0.57 Identities = 32/155 (20%), Positives = 63/155 (40%), Gaps = 11/155 (7%) Query: 527 VQFECQVEGYPRPQ-ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +Q +C ++ Y ITW+ + S F++ ++AT+ + E +D GT++ V Sbjct: 741 IQLQCHMKYYTSEMNITWYHGETKLLHSDKFKIG-GTPSMATMEVIEPTEKDQGTYSIVI 799 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYV 645 + T L E H + + ++ G+P + + Sbjct: 800 VDPENSHKRTLNLSGEVYEKAHAEFLQLNLHVCVCLDR--GKVVGGLPDVVT-------I 850 Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENI 680 E + L C + P+P ++WL G E+ PD+ + Sbjct: 851 MEKKTLSLTCTVCGDPKPQVSWLKSGAEVEPDDKV 885 >UniRef50_A6NI63 Cluster: Uncharacterized protein MYOM3; n=42; Tetrapoda|Rep: Uncharacterized protein MYOM3 - Homo sapiens (Human) Length = 1441 Score = 104 bits (249), Expect = 3e-20 Identities = 131/533 (24%), Positives = 218/533 (40%), Gaps = 73/533 (13%) Query: 1591 LVTAVIEGIPPPEVIWYKNGNKLE----NDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 L+T ++ PPP+V WYKN +++ +Y IT + I+ S+ YT+ Sbjct: 172 LLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVR 231 Query: 1647 ASNTAGTSS--VEVTLKVY-DKPSKPEGPVIMREISRESV--TIEWKPPL--DDGGLELT 1699 N G +S +V ++ Y K + + + R SV T KP + L+ Sbjct: 232 VKNAHGQASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLS 291 Query: 1700 -KYAIEKHEPDNNRWI------------KVADVDRD--VETYCIQKLNENCEYMFRVIAQ 1744 ++ + + ++ +W K+ DR ++ C K +E YM RV Sbjct: 292 CLFSEDVLDAESIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGL-YMVRV--- 347 Query: 1745 NPVGFSEALESEPIVIKTA-LDVPSXXXXXXXXXXID--NESVYITWFPSEKNGGSPIID 1801 P F +S ++++ A + P +D + + +TW P G+PI Sbjct: 348 -PSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITA 406 Query: 1802 YKVEIKQ-EGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTS---------- 1848 Y +E Q E +W R IQ L +Y+FR+ A + +G+S Sbjct: 407 YTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVV 466 Query: 1849 ------------LPYTSDDKITIGK-----TLTPPSQPRNFVVSESTSRSVTLKWTEPES 1891 +P+ +KITI T+T PS P N SE V L W EP Sbjct: 467 MGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSP 526 Query: 1892 NGGSPITNYIIEFKTVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 +P+T Y +E + +W I + + ++++K +FR+ A N G+S Sbjct: 527 RDRAPLT-YSLEKSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSD 585 Query: 1951 PTE-SQSVRLE-KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 P+E S+ + L AT+P PP R +++ +T W P D LLGY I R V Sbjct: 586 PSEPSEPIALRGPPATLP-PPAQVQAFRDTQTSVSLT-W-DPVKD--PELLGYYIYSRKV 640 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 + W V + +F + L Y + + +E G+ E + EP +V Sbjct: 641 GTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRV 693 Score = 83.8 bits (198), Expect = 5e-14 Identities = 80/332 (24%), Positives = 130/332 (39%), Gaps = 16/332 (4%) Query: 1632 IKELKRSHSSKYTIEASNTAGTS-----SVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + +L++ S + + A N G S S + L+ P V ++ SV++ Sbjct: 562 VLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLT 621 Query: 1687 WKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 W P D EL Y I + + W V + + + L EY F V + + Sbjct: 622 WDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSE 678 Query: 1747 VGFSEA-LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE 1805 G E+ +EPI +K AL PS NE V I W P ++ GG I+ Y ++ Sbjct: 679 AGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMV-IGWKPPKRRGGGKILGYFLD 737 Query: 1806 IKQ-EGKKWKXXXXXX--XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK- 1861 E W ++ L Y+FR A N G + Sbjct: 738 QHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEW 797 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGS 1921 T+ P P + SE + S+ L+W P G P+T Y + F+ + W K VT G Sbjct: 798 TMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQW-KPVTPGPI 856 Query: 1922 VHEHC-IENIKEKDEIIFRISAENTVGVSLPT 1952 H + +++ +F++ A N+ G+ P+ Sbjct: 857 SGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPS 888 Score = 70.5 bits (165), Expect = 5e-10 Identities = 56/222 (25%), Positives = 93/222 (41%), Gaps = 11/222 (4%) Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIG---KTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 +Y FR+ A N+ G S P + I + TL PP+Q + F T SV+L W +P Sbjct: 570 SYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAF---RDTQTSVSLTW-DPV 625 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 + + Y I + V W + + ++ E F + + + GV Sbjct: 626 KD--PELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGE 683 Query: 1951 PTES-QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVT 2009 + + + +R+++ PS P + G N ++ W P+ GG +LGY + D Sbjct: 684 SSAATEPIRVKQALATPSAPYG-FALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSE 742 Query: 2010 KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 + W V + + T + DL E H Y R A N G+ E Sbjct: 743 ELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGE 784 Score = 64.1 bits (149), Expect = 4e-08 Identities = 63/279 (22%), Positives = 116/279 (41%), Gaps = 36/279 (12%) Query: 1227 VTWYKKKSVIED----TEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLK 1280 VTWYK + I+ K+ + ++ +L IR+C +D YT + +A ++++ K Sbjct: 185 VTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAK 244 Query: 1281 VEVVEFPPKIVDYEREY---------------------RIKRGSDVTLLVDYQAFPQPND 1319 V V + K ++ E R K ++ L + Sbjct: 245 VLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLSCLFSEDVLDAESI 304 Query: 1320 EWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 +W + +++ + K + ASL + D G+Y +R+ + G + V + D Sbjct: 305 QWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRD 364 Query: 1380 ----KPSPPGKP-NI--LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 P PG P N+ L+++ + + W P +T + I Y +E + ++ EWI+ Sbjct: 365 AEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE 424 Query: 1433 IT--KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + IQ L SYRFR A++ V S S+ +E Sbjct: 425 APGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASE 463 Score = 61.7 bits (143), Expect = 2e-07 Identities = 48/215 (22%), Positives = 81/215 (37%), Gaps = 6/215 (2%) Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 ++A T + V + PS P G ++ + + I WKPP GG ++ Y +++H+ Sbjct: 684 SSAATEPIRVK-QALATPSAPYGFALLN-CGKNEMVIGWKPPKRRGGGKILGYFLDQHDS 741 Query: 1709 DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPS 1768 + W V + L+E Y FR A N G E + +P Sbjct: 742 EELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQ 801 Query: 1769 -XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWK--XXXXXXXXXA 1824 + S+ + W P G P+ Y V ++EG ++WK Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHL 861 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITI 1859 R+ L +Y F++ A N G P D + + Sbjct: 862 RVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLL 896 Score = 48.0 bits (109), Expect = 0.003 Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN---VA 566 P F LR + +TV C V+ P PQ+TW++ I P Y N + Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 +L IR ED+ T+T KNA G ASS +++V L Sbjct: 214 SLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVRTYL 251 Score = 46.8 bits (106), Expect = 0.007 Identities = 30/141 (21%), Positives = 67/141 (47%), Gaps = 11/141 (7%) Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMN---VTILDKPS---PPGKPNILEIDS 1394 +S + +E + ++++R N G +D + + P+ PP + Sbjct: 556 RSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQ 615 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFR 1452 +S+++ WD ++ ++ Y + +++ T+EW +V N I T+ ++ L+T Y F Sbjct: 616 TSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFC 672 Query: 1453 AYAVNEVDISDASETTEYYKV 1473 +V+E + ++S TE +V Sbjct: 673 VRSVSEAGVGESSAATEPIRV 693 Score = 46.4 bits (105), Expect = 0.009 Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 21/205 (10%) Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKK 796 PLK +G + + TW +K +++ + T + D + IL PK Sbjct: 1230 PLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIWLHILDPKD 1289 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE----PPLFI---NRFQEI------- 842 D+G YTL+ + + + S ++ + + AE L I NR + + Sbjct: 1290 -SDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKVVRGLPDVA 1348 Query: 843 TVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSG 902 T+ E T+ L V+ +P P I+W +N++ ++ + G + + I V+SE DSG Sbjct: 1349 TIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSE-DSG 1407 Query: 903 DYKCVASNSAGKSSHGARVTIDVEK 927 Y N G S +VTI V K Sbjct: 1408 RYGVFVKNKYG--SETGQVTISVFK 1430 Score = 46.0 bits (104), Expect = 0.011 Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 4/92 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 PSPP + EI + + + W+EP + + Y +E I + W ++ + + + Sbjct: 501 PSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-YSLEKSVIGSGTWEAISSESPVRSPR 559 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ +L+ SY FR A+N+ +SD SE +E Sbjct: 560 FAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSE 591 Score = 44.8 bits (101), Expect = 0.026 Identities = 23/94 (24%), Positives = 45/94 (47%), Gaps = 2/94 (2%) Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITK 1435 + +P PP E+ ++S+ + W+ P G + Y V +QE + +W ++ I+ Sbjct: 799 MPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISG 858 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 T + +L+ SY F+ A+N + S T+ Sbjct: 859 THLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTD 892 Score = 44.4 bits (100), Expect = 0.035 Identities = 19/79 (24%), Positives = 38/79 (48%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T ++ G P PE+ W KN + Y + + I I+++ S +Y + N Sbjct: 1358 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKY 1417 Query: 1652 GTSSVEVTLKVYDKPSKPE 1670 G+ + +VT+ V+ +P+ Sbjct: 1418 GSETGQVTISVFKHGDEPK 1436 Score = 41.5 bits (93), Expect = 0.25 Identities = 37/167 (22%), Positives = 67/167 (40%), Gaps = 12/167 (7%) Query: 1320 EW-IVNSKIIKKCKHTKPSIDS-KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 EW VN+K I+ + T P + + K ++ V G E++ + + Sbjct: 644 EWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVG------ESSAATEPIRVKQA- 696 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITK 1435 L PS P +L + + I W P+ G I+ Y ++ + + +W +V I Sbjct: 697 LATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPT 756 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 + +L Y FRA A N + + S + ++ KE + P Sbjct: 757 RVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFE-CKEWTMPQP 802 Score = 39.9 bits (89), Expect = 0.75 Identities = 92/398 (23%), Positives = 152/398 (38%), Gaps = 51/398 (12%) Query: 458 VQKHLTEEKGWVPAQYLMDENNYTQYLQKKLNEKIDKL--PVFEKPTSEEQSMAPIFVEK 515 +Q E+KG AQ L D Q +++ DKL K ++ P F Sbjct: 1067 IQNLSEEDKGSYTAQ-LQDGKAKNQITLTLVDDDFDKLLRKADAKRRDWKRKQGPYFERP 1125 Query: 516 LRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP 575 L+ K T D CQV Q+T K FQ ++ A + + P Sbjct: 1126 LQWKVTED-------CQV------QLTCKASVTNTKKETRFQWFFQR---AEMPDGQYDP 1169 Query: 576 EDAGTFTCVAKNAAGFASSTTELIVEAPLSD-HGSEMTVXXXXXXXXXXXXADILEGIPP 634 E C+ + + S + I A +SD G + T+ ++ G Sbjct: 1170 ETGTGLLCIEEASL---SKKDKGIYRAMVSDDRGEDDTILDLTGDALDAIFTEL--GRIG 1224 Query: 635 TFSKKP-KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 S P K Q +EG I + + + W K + + + I D Sbjct: 1225 ALSATPLKIQGTEEGIRIFSKVKYYNVEYMKTTWFHKDKRLESGDRIRTGTTLDEIW--- 1281 Query: 694 VLKITNVKKFQEGTYTV-VAVNRE---------GEA---SLPIVLKIKTG---EKEPPQV 737 L I + K +G YT+ +A +E G+A ++ ++KT EK +V Sbjct: 1282 -LHILDPKDSDKGKYTLEIAAGKEVRQLSTDLSGQAFEDAMAEHQRLKTLAIIEKNRAKV 1340 Query: 738 IEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSITILK 793 + L + + + +++ L+ V G+P P I+W KN++PV L + G +ITI K Sbjct: 1341 VRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEK 1400 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 +D G Y + +N G I+V + +E E Sbjct: 1401 VNS-EDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKE 1437 Score = 37.9 bits (84), Expect = 3.0 Identities = 22/89 (24%), Positives = 47/89 (52%), Gaps = 6/89 (6%) Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD----GDTHSITILKPK 795 PL+S V + +V+L+ V +P P +TW KN+ + ++ + + + L+ + Sbjct: 159 PLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIR 218 Query: 796 K--VKDEGVYTLKAENSEGIAETSAVITV 822 + ++D YT++ +N+ G A + A + V Sbjct: 219 RCAIEDSATYTVRVKNAHGQASSFAKVLV 247 Score = 37.5 bits (83), Expect = 4.0 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 9/97 (9%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP------SETITQNFDGE 886 P F + V E T+ L V +P P +TWY+N+ I P IT N+ Sbjct: 154 PWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLL 213 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++E+ ++ DS Y N+ G++S A+V + Sbjct: 214 SLEIRRCAIE---DSATYTVRVKNAHGQASSFAKVLV 247 >UniRef50_Q9GPP6 Cluster: Roundabout 3; n=4; Diptera|Rep: Roundabout 3 - Drosophila melanogaster (Fruit fly) Length = 1342 Score = 103 bits (248), Expect = 4e-20 Identities = 88/353 (24%), Positives = 152/353 (43%), Gaps = 25/353 (7%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 I +A +D G + A + + P + P Q V EG+ + CR+ Sbjct: 180 IQDARQTDEGQYQCIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVG 239 Query: 659 AIPEPDIAWLFKGEE-IVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P PD+ WL +P + +SV + L++ V EG Y+ A N G Sbjct: 240 GDPMPDVLWLRTASGGNMPLDRVSVLEDRS-------LRLERVTIADEGEYSCEADNVVG 292 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWC-KNNK--- 773 + L + PP+ I+ S V G + +GNP+PTI W KNN Sbjct: 293 AITAMGTLTVYA----PPKFIQRPASKSVELGADTSFECRAIGNPKPTIFWTIKNNSTLI 348 Query: 774 -----PVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 P+ + + + HSI L + D+ + L +E +A ++ + + ++E Sbjct: 349 FPGAPPLDRFHSLNTEEGHSILTLTRFQRTDKDLVILCNAMNE-VASITSRVQLSLDSQE 407 Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888 + PP+ I+ T+ K L + P P+I+WYR+ + PS + G+ Sbjct: 408 DRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSGD-- 465 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 L+I+++D + D G Y CVAS+ AGKS+ + I++ +K + +T+ Sbjct: 466 -LIISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKFYRAPEQTK 517 Score = 68.5 bits (160), Expect = 2e-09 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 20/227 (8%) Query: 734 PPQVIE-PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-----TKSDGDTH 787 PP+++E P+ + + R E L+ + G+P PTI W K+ P+K LP T G Sbjct: 22 PPRIVEHPIDTTVPRH-EPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLF 80 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKE 846 + ++ ++ D G+Y +A+N G+A + +A + V +E P Q + + Sbjct: 81 FLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEP------QNTRIAQ 134 Query: 847 KGTIKLVARVTRN-PVPSITWYRNNEIIS-PSETITQNFDGENIELVITNVDSEIDSGDY 904 T L R P P++TW + + + + DG N L I + + D G Y Sbjct: 135 GDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN--LAIQDA-RQTDEGQY 191 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 +C+A N G + T+ V ++ EG +V C+ Sbjct: 192 QCIAKNPVG-VRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCR 237 Score = 68.1 bits (159), Expect = 2e-09 Identities = 80/317 (25%), Positives = 125/317 (39%), Gaps = 25/317 (7%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN---EIISPSETITQNFD 884 + + PP + + TV L + +P P+I WY++ +I+ S IT Sbjct: 18 QGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAG 77 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEG 943 G L + N E D+G Y C A N G + S A + + V + F Q + +G Sbjct: 78 G-LFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNT-RIAQG 135 Query: 944 KTVILECQTSH-----TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 T +LEC TV+ K K ++ G I+ G D G + Sbjct: 136 DTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN---LAIQDARQTDEGQYQ 192 Query: 999 CIVKD----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDG 1053 CI K+ +E+S + P IR D V E + + DV+W R Sbjct: 193 CIAKNPVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTA 252 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTV-VELPPEII 1110 ++ + R L + ++ DEGEYSC + + TA T+ V PP+ I Sbjct: 253 SGGNMPLDRVSVLED---RSLRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFI 309 Query: 1111 TRLQNQKVNKGNKATFE 1127 R ++ V G +FE Sbjct: 310 QRPASKSVELGADTSFE 326 Score = 59.3 bits (137), Expect = 1e-06 Identities = 103/445 (23%), Positives = 168/445 (37%), Gaps = 48/445 (10%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQF---SNHIQLTIDGKKQ 1161 PP I+ + V + AT + ++W+KDG ++ S+ I L G Sbjct: 22 PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFF 81 Query: 1162 KLKIYDCDLD-DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT------DA 1214 LK+ + + DAG Y CE N + ++ + EF L P NT A Sbjct: 82 -LKVVNSRRETDAGIYWCEAKNE--LGVARSRNATLQVAVLRDEFRLEPQNTRIAQGDTA 138 Query: 1215 YLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 L P + VTW KK D E + V L I+ + D+ +Y C+ + Sbjct: 139 LLECAAPRGIPEPTVTW-KKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKN 197 Query: 1273 AKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 + L V P I+ + + G+ VT P P+ W+ + Sbjct: 198 PVGVRESSLATLKVHVKPYIIRGPHDQTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNM 257 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS----PPGK 1386 ++ +S L +++V D G Y +N G +T+ P P K Sbjct: 258 PLDRVSVLEDRS--LRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRPASK 315 Query: 1387 PNILEIDSSSINICWDEPENT------GNSTIIYY----VVEYQEIDTTEWISVKNITKT 1436 L D+S P+ T NST+I+ + + ++T E S+ +T+ Sbjct: 316 SVELGADTSFECRAIGNPKPTIFWTIKNNSTLIFPGAPPLDRFHSLNTEEGHSILTLTRF 375 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLKNITTE 1494 Q +T+ A+NEV AS T+ + + + P + P+ N T Sbjct: 376 Q------RTDKDLVILCNAMNEV----ASITSRVQLSLDSQEDRPPPIIISGPV-NQTLP 424 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDG 1519 L C G+P P ++WYRDG Sbjct: 425 IKSLATLQCKAIGLPSPTISWYRDG 449 Score = 59.3 bits (137), Expect = 1e-06 Identities = 79/328 (24%), Positives = 130/328 (39%), Gaps = 30/328 (9%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMHM 690 PP + P V L C+ P P I W G +I+P + + + + Sbjct: 22 PPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSH-RITLPAGGLF 80 Query: 691 YCSVLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 + LK+ N ++ + G Y A N G A S L++ E +EP + I Q Sbjct: 81 F---LKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDE--FRLEPQNTRIA-Q 134 Query: 749 GESVILS-AQVVGNPRPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVY 803 G++ +L A G P PT+TW K + + +K DG +I + + DEG Y Sbjct: 135 GDTALLECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAI---QDARQTDEGQY 191 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 A+N G+ E S++ T++ + P I + TV E ++ RV +P+P Sbjct: 192 QCIAKNPVGVRE-SSLATLKVHVK-----PYIIRGPHDQTVLEGASVTFPCRVGGDPMPD 245 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W R + + ++ L + D G+Y C A N G + +T+ Sbjct: 246 VLWLRTASGGNMPLDRVSVLEDRSLRLERVTI---ADEGEYSCEADNVVGAITAMGTLTV 302 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQ 951 + KS E G EC+ Sbjct: 303 YAPPKFIQRPASKSVEL--GADTSFECR 328 Score = 57.2 bits (132), Expect = 5e-06 Identities = 52/180 (28%), Positives = 83/180 (46%), Gaps = 24/180 (13%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSH-SSKYTIEASNTAGTSS- 1655 G+P P + WY++G ++ + NITT + + I +L R YT AS+ AG S+ Sbjct: 437 GLPSPTISWYRDGIPVQPSSKLNITT---SGDLIISDLDRQQDQGLYTCVASSRAGKSTW 493 Query: 1656 -----VEV----TLKVYDK------PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK 1700 +E+ +K Y PS P P I+ + ++TI W G Sbjct: 494 SGFLRIELPTNPNIKFYRAPEQTKCPSAPGQPKIL-NATASALTIVWPTSDKAGASSFLG 552 Query: 1701 YAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPI 1758 Y++E + + +R WI +A + ++ L + YMF V A+N +GFS SEPI Sbjct: 553 YSVEMYCTNQSRTWIPIAS-RLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEPI 611 Score = 52.4 bits (120), Expect = 1e-04 Identities = 57/214 (26%), Positives = 84/214 (39%), Gaps = 19/214 (8%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----- 1538 VE P+ + T +E L C G P P + WY+DG LK ++ Sbjct: 26 VEHPI-DTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRITLPAGGLFFLKV 84 Query: 1539 --XXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C A N+ G T V ++ + + N I Q GD L+ Sbjct: 85 VNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRIAQ----GDTALL 140 Query: 1593 T-AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 A GIP P V W K G KL+ + + + + + I++ +++ +Y A N Sbjct: 141 ECAAPRGIPEPTVTWKKGGQKLDLEGSKRVRIVDGGN-LAIQDARQTDEGQYQCIAKNPV 199 Query: 1652 GT-SSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 G S TLKV+ KP GP + SVT Sbjct: 200 GVRESSLATLKVHVKPYIIRGPHDQTVLEGASVT 233 Score = 52.0 bits (119), Expect = 2e-04 Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 12/172 (6%) Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS- 1562 G+P+P VTW + G+KL + + + Y+CIA N G E+S Sbjct: 147 GIPEPTVTWKKGGQKLDLEGSKRVRIVDGGNLAIQDARQTDEGQYQCIAKNPVGVRESSL 206 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK--NGNKLENDKEYN 1620 + + KP I D Q G + G P P+V+W + +G + D+ Sbjct: 207 ATLKVHVKPYIIRGPHD--QTVLEGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDR--- 261 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++ E S +R++ + + +Y+ EA N G + TL VY P + P Sbjct: 262 VSVLEDRS-LRLERVTIADEGEYSCEADNVVGAITAMGTLTVYAPPKFIQRP 312 Score = 49.6 bits (113), Expect = 0.001 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 3/101 (2%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+E PI + + P S +C+ G P P I+W+R ++PS + Sbjct: 405 SQEDRPPPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSG 464 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 D + + + R+ +D G +TCVA + AG ++ + L +E P Sbjct: 465 DLIISDLDRQ---QDQGLYTCVASSRAGKSTWSGFLRIELP 502 Score = 47.6 bits (108), Expect = 0.004 Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWISV-KNITKTQT 1438 PS PG+P IL +S++ I W + G S+ + Y VE Y + WI + +++ Sbjct: 519 PSAPGQPKILNATASALTIVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIF 578 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++++L ++Y F A N + S S +E Sbjct: 579 TVESLTQGAAYMFIVRAENSLGFSPPSPISE 609 Score = 41.5 bits (93), Expect = 0.25 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 5/114 (4%) Query: 1948 VSLPTES--QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAI 2005 + LPT + R + PS P P + S + + W T + G + LGY++ + Sbjct: 499 IELPTNPNIKFYRAPEQTKCPSAPGQPKILNATASALTIV-WPTSDKAGASSFLGYSVEM 557 Query: 2006 RDVTKTM-WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ W+ + ++ F + L++ YM + A N +G S P EP Sbjct: 558 YCTNQSRTWIPIAS-RLSEPIFTVESLTQGAAYMFIVRAENSLGFSPPSPISEP 610 Score = 40.3 bits (90), Expect = 0.57 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G++V F C+V G P P + W R + D +D +L + V D G ++ Sbjct: 228 EGASVTFPCRVGGDPMPDVLWLRTASGGNMPLDRVSVLED---RSLRLERVTIADEGEYS 284 Query: 583 CVAKNAAGFASSTTELIVEAP 603 C A N G ++ L V AP Sbjct: 285 CEADNVVGAITAMGTLTVYAP 305 Score = 37.5 bits (83), Expect = 4.0 Identities = 42/155 (27%), Positives = 52/155 (33%), Gaps = 5/155 (3%) Query: 500 KPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK--PSQDFQ 557 K T + S P VE P C+ EG P P I W++ +K P Sbjct: 13 KWTHAQGSHPPRIVEHPIDTTVPRHEPATLNCKAEGSPTPTIQWYKDGVPLKILPGSHRI 72 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH-GSEMTVXXX 616 V+ DAG + C AKN G A S + A L D E Sbjct: 73 TLPAGGLFFLKVVNSRRETDAGIYWCEAKNELGVARSRNATLQVAVLRDEFRLEPQNTRI 132 Query: 617 XXXXXXXXXADILEGIP-PTFSKKPKAQYVD-EGS 649 GIP PT + K Q +D EGS Sbjct: 133 AQGDTALLECAAPRGIPEPTVTWKKGGQKLDLEGS 167 Score = 37.1 bits (82), Expect = 5.3 Identities = 36/133 (27%), Positives = 56/133 (42%), Gaps = 13/133 (9%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIE-LTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP II+ NQ + + AT + + + + W++DG +Q S+ + +T G L Sbjct: 411 PPIIISGPVNQTLPIKSLATLQCKAIGLPSPTISWYRDGIPVQPSSKLNITTSG---DLI 467 Query: 1165 IYDCD-LDDAGEYSC----EVGNSKCTAILTVE---EPSINFTLRLPEFILVPANTDAYL 1216 I D D D G Y+C G S + L +E P+I F R PE P+ Sbjct: 468 ISDLDRQQDQGLYTCVASSRAGKSTWSGFLRIELPTNPNIKF-YRAPEQTKCPSAPGQPK 526 Query: 1217 TVEIPDETLDVTW 1229 + L + W Sbjct: 527 ILNATASALTIVW 539 Score = 36.7 bits (81), Expect = 7.0 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 1786 ITWFPSEKNGGSPIIDYKVEI--KQEGKKW-KXXXXXXXXXARIQKLSINTTYQFRIYAR 1842 I W S+K G S + Y VE+ + + W ++ L+ Y F + A Sbjct: 537 IVWPTSDKAGASSFLGYSVEMYCTNQSRTWIPIASRLSEPIFTVESLTQGAAYMFIVRAE 596 Query: 1843 NEIGTSLPYTSDDKITIGK 1861 N +G S P + IT GK Sbjct: 597 NSLGFSPPSPISEPITAGK 615 >UniRef50_Q49AK4 Cluster: DCC protein; n=9; Euteleostomi|Rep: DCC protein - Homo sapiens (Human) Length = 772 Score = 103 bits (248), Expect = 4e-20 Identities = 123/585 (21%), Positives = 221/585 (37%), Gaps = 34/585 (5%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXX 1541 +++P + E + + C+ G P P TW R + +L++ K + Sbjct: 177 LQRPSNVVAIEGKDAVLEGCV-SGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVT 235 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C+ + + S + + P ++ + E+ T + G P Sbjct: 236 DDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECT--VSGKPV 293 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P V W KNG+ + + I S +RI + +S Y A N AG + L Sbjct: 294 PTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL- 349 Query: 1662 VYDKPSKPEGPVIMRE--------ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRW 1713 + KP+ P V+ +S V + W+PP + G T E DN Sbjct: 350 IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRER 409 Query: 1714 IKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 ++ + L Y FRV+A N G E+ + + + L VP Sbjct: 410 ALNTTQPGSLQ-LTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENL 468 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINT 1833 S+ ITW P G P+ Y++ + + +++ L T Sbjct: 469 QAVST-SPTSILITWEPPAYANG-PVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFT 526 Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 Y R A N G + ++DD + + P + P+N + SRS+ + W P S Sbjct: 527 EYSLRFLAYNRYGPGV--STDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGT 584 Query: 1894 GSP-ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 + IT Y I + + ++ T+ + + +++ + F++SA G P+ Sbjct: 585 QNGFITGYKIRHRKTTRRG--EMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPS 642 Query: 1953 ESQSVRLEKH----ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDV 2008 + ++ + VP P++ L +R +N ++ SW TP + + GY I Sbjct: 643 NWYTAETPENDLDESQVPDQPSS-LHVR-PQTNCIIMSW-TPPLNPNIVVRGYIIGYG-- 697 Query: 2009 TKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 + + E +VD ++I L + Y+I + A N G PL Sbjct: 698 VGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPL 742 Score = 90.2 bits (214), Expect = 5e-16 Identities = 150/723 (20%), Positives = 265/723 (36%), Gaps = 50/723 (6%) Query: 1263 QCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 QCE + L D+ S +V V P + + G V L + P P W Sbjct: 50 QCEAS--LGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHW 107 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG-HADVEMNVTILDK 1380 N + + + S +L I +++ D GIY+ N E V IL Sbjct: 108 QKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSD 167 Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 P + L+ S+ + I G ++ V + W+ + + + ++ Sbjct: 168 PGLHRQLYFLQRPSNVVAI-------EGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKK 220 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE---TKIQSPTVEKPLKNITTEPNE 1497 +L S+ ++ + T + + T + P N+ + Sbjct: 221 YSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESM 280 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKK-LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 DIE C G P P V W ++G + + Y+C+A N+ Sbjct: 281 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEA 340 Query: 1557 GEVETSCVVGIQQKPVITISN------EDIK----QKHKVGDEWLVTAVIEG-IPPPEVI 1605 G +TS + I KP I S+ D+ V W A +G I V Sbjct: 341 GNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVF 399 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 + + G+ E + N TT+ + + + LK + + A N G +KV + Sbjct: 400 FSREGDNRE--RALN-TTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQ 456 Query: 1666 PS-KPEGPVI-MREISRE--SVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 P + GPV ++ +S S+ I W+PP G + Y + E K +++ Sbjct: 457 PELQVPGPVENLQAVSTSPTSILITWEPPAYANG-PVQGYRLFCTEVSTG---KEQNIEV 512 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 D +Y ++ L + EY R +A N G + ++ I + T DVPS +++ Sbjct: 513 DGLSYKLEGLKKFTEYSLRFLAYNRYG--PGVSTDDITVVTLSDVPSAPPQNVSLEVVNS 570 Query: 1782 ESVYITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRI 1839 S+ ++W P + I YK+ ++ ++ + + L + Y F++ Sbjct: 571 RSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQV 630 Query: 1840 YARNEIGTSLP---YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 A GT P YT++ P QP + V T+ + + WT P N Sbjct: 631 SAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTN-CIIMSWT-PPLNPNIV 688 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQ 1955 + YII + G + + V V + IE ++ + + A N G +P ES Sbjct: 689 VRGYIIGYGV--GSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESA 746 Query: 1956 SVR 1958 + R Sbjct: 747 TTR 749 Score = 81.4 bits (192), Expect = 2e-13 Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 20/280 (7%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G +LL+C ++ P P I W +++ P S + + L+I+ ++ G Sbjct: 88 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVV----LPSGALQISRLQPGDIGI 143 Query: 708 YTVVAVN----REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 Y A N R G + +L G ++ +++ +G+ +L V G P Sbjct: 144 YRCSARNPASSRTGNEAEVRILS-DPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPP 202 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 P+ TW + + ++ K S ++ D G+YT SA +TV Sbjct: 203 PSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV- 261 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 PP F+N + E I+ V+ PVP++ W +N +++ PS+ Q Sbjct: 262 ------LVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYF-QIV 314 Query: 884 DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 G N+ ++ V S D G Y+CVA N AG + A++ + Sbjct: 315 GGSNLR-ILGVVKS--DEGFYQCVAENEAGNAQTSAQLIV 351 Score = 77.0 bits (181), Expect = 5e-12 Identities = 83/326 (25%), Positives = 129/326 (39%), Gaps = 21/326 (6%) Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 K EG Y A G++ I K P + + +S+ G++V+L +V+G Sbjct: 43 KPDEGLYQCEA--SLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGE 100 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAETSAV 819 P PTI W KN + + +P S L+ +++ D G+Y A N + T Sbjct: 101 PMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS-SRTGNE 159 Query: 820 ITVEEPTEENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 V ++ L F+ R + E L V+ P PS TW R E+I Sbjct: 160 AEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSK 219 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 G N L+I+NV + DSG Y CV + S A +T+ V F+ H Y Sbjct: 220 KYSLLGGSN--LLISNVTDD-DSGMYTCVVTYKNENISASAELTVLVPP-WFLNHPSNLY 275 Query: 939 ETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 E + EC S + W N + D+ +I+ D G Sbjct: 276 -AYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV---GGSNLRILGVVKSDEGF 331 Query: 997 IKCIVKDQ----ETSTMLVV-KETIP 1017 +C+ +++ +TS L+V K IP Sbjct: 332 YQCVAENEAGNAQTSAQLIVPKPAIP 357 Score = 71.3 bits (167), Expect = 3e-10 Identities = 80/302 (26%), Positives = 115/302 (38%), Gaps = 35/302 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G TV +C+V G P P I W + + P + A L I + P D G + C Sbjct: 88 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGA-LQISRLQPGDIGIYRC 146 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A+N A +S T LSD G + F ++P Sbjct: 147 SARNPA--SSRTGNEAEVRILSDPGLHRQLY---------------------FLQRPSNV 183 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 EG D +LE + P P WL +GEE++ + ++ + S L I+NV Sbjct: 184 VAIEGKDAVLEGCVSGYPPPSFTWL-RGEEVIQLRSKKYSL-----LGGSNLLISNVTDD 237 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G YT V + S L + PP + ++ + + V G P Sbjct: 238 DSGMYTCVVTYKNENISASAELTVLV----PPWFLNHPSNLYAYESMDIEFECTVSGKPV 293 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 PT+ W KN V ++ IL K DEG Y AEN G A+TSA + V Sbjct: 294 PTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVK-SDEGFYQCVAENEAGNAQTSAQLIVP 352 Query: 824 EP 825 +P Sbjct: 353 KP 354 Score = 68.1 bits (159), Expect = 2e-09 Identities = 95/443 (21%), Positives = 174/443 (39%), Gaps = 42/443 (9%) Query: 1083 DEGEYSC--ILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL 1136 DEG Y C L D S TA+V V P +++ ++ G+ + E+ G+ + Sbjct: 45 DEGLYQCEASLGDSGSIISRTAKVAVAG-PLRFLSQTESVTAFMGDTVLLKCEVI-GEPM 102 Query: 1137 --VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA------I 1188 + W K+ ++ + L+I D G Y C N + + Sbjct: 103 PTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEV 162 Query: 1189 LTVEEPSIN---FTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYKKKSVIE-DTEKFT 1243 + +P ++ + L+ P ++ DA L + TW + + VI+ ++K++ Sbjct: 163 RILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYS 222 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRG 1302 L+ L+I T+DD YTCV+ E+ V PP +++ Sbjct: 223 LLGG---SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYES 279 Query: 1303 SDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 D+ P P W+ N ++ + + S +L I V +D G Y+ Sbjct: 280 MDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGS---NLRILGVVKSDEGFYQCVA 336 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNI---------LEIDSSSINICWDEPENTGNSTII 1413 EN G+A + I+ KP+ P + + + S + + W P + Sbjct: 337 ENEAGNAQTSAQL-IVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKGNIQT 395 Query: 1414 YYVVEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 + V +E D E ++ Q ++ NLK + Y FR A NE E+++ K Sbjct: 396 FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNE---WGPGESSQPIK 452 Query: 1473 VIKETKIQSPTVEKPLKNITTEP 1495 V + ++Q P + L+ ++T P Sbjct: 453 VATQPELQVPGPVENLQAVSTSP 475 Score = 55.2 bits (127), Expect = 2e-05 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+ + + ++FEC V G P P + W + ++ PS FQ+ + L Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIV----GGSNLR 320 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I V D G + CVA+N AG A ++ +LIV P Sbjct: 321 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKP 354 Score = 39.9 bits (89), Expect = 0.75 Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 3/81 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G E V GYP P TW R +I+ N L+I V +D+G +T Sbjct: 187 EGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSN---LLISNVTDDDSGMYT 243 Query: 583 CVAKNAAGFASSTTELIVEAP 603 CV S++ EL V P Sbjct: 244 CVVTYKNENISASAELTVLVP 264 >UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG8967-PA - Tribolium castaneum Length = 1094 Score = 103 bits (247), Expect = 5e-20 Identities = 146/668 (21%), Positives = 266/668 (39%), Gaps = 72/668 (10%) Query: 1049 WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV------ 1102 WE +G I ++ HI ++ D G+++CI D + + ++ Sbjct: 56 WELNGSKIANTTRRHQQGSNLHITRV----DRERDSGQFTCIAEDSTSSLAGSIRSSEAS 111 Query: 1103 --VELPPEIITRLQNQK----VNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLT 1155 ++ E+ +LQ + +++G+ T GD WF++ + S+ I++ Sbjct: 112 LNIQWIDEVSVQLQEPESASFISRGSDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEI- 170 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVP 1209 KK++L I + D G Y C N S L V +P LVP Sbjct: 171 ---KKKRLHIKNVGPSDNGVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVP 227 Query: 1210 ANTDAYLTVEIPDETLDVT-WYKKKSV--IEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 AY + + +VT WY KK +E+ +KF + S+ TL I DQ Y Sbjct: 228 QGGTAYFDCQY--QQAEVTEWYFKKDTRPLENGKKFVIHSN---GTLQINDVQGKDQGFY 282 Query: 1267 TCVLLDAKST-------TKLKVE------VVEFPPKIVDYEREYRIKRGSDVTLL-VDYQ 1312 +CV + ++ST +LK+ V F P + + + G L ++ Sbjct: 283 SCVGIRSESTEIPQSYIAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPD 342 Query: 1313 AFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE 1372 + P P +W +N+ + +D L I+KV AG Y EN G + Sbjct: 343 SLP-PAKKWWLNTGGHTVSDSGEVRVDD--GRLIIEKVRMDHAGNYTCVAENMAGKTEKI 399 Query: 1373 MNVTILDKPSPPGKPNILEIDSS--SINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + + +L+KP +P + +D + S+ C EP+N + +V++++ + Sbjct: 400 IELVVLNKPVVTAQPLSVTVDENEPSMLTCDYEPKNH------FTIVKWRKDGKSLRHDF 453 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN 1490 + + I+ K N+S R ++ + ++ + +EK LK Sbjct: 454 GENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISVIEK-LKF 512 Query: 1491 ITTEPNEDIELT------CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXX 1544 + N+ +EL C G P P +TW + G+ ++ N Sbjct: 513 VPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRIISMN-GTLVFNGVLNED 571 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C+A N G + + + + P ++ ++ + + G + V+EG P P + Sbjct: 572 KGKYTCVATNSQGVINVTINIDVVVAPKFSVEPKNPTEVTE-GQSVTIDCVVEGDPKPTI 630 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W KN ND +++ T + + I E+ R +KY A N+AG + EV L V+ Sbjct: 631 HWDKNLKM--NDFDHSRFTVLENGTLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHS 688 Query: 1665 KPS-KPEG 1671 + P+G Sbjct: 689 RDGYHPDG 696 Score = 89.8 bits (213), Expect = 7e-16 Identities = 148/712 (20%), Positives = 281/712 (39%), Gaps = 85/712 (11%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 KE P E +++ V QG+SV L +V T W N + A T+ ++ I Sbjct: 20 KEDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKI-ANTTRRHQQGSNLHI 78 Query: 792 LKPKKVKDEGVYTLKAENSE-----GIAETSAVITVEEPTE-----ENAEPPLFINRFQE 841 + + +D G +T AE+S I + A + ++ E + E FI+R + Sbjct: 79 TRVDRERDSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASFISRGSD 138 Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 +T++ + W+RN++ + S+ I + + L I NV D+ Sbjct: 139 VTLR--------CHTDASGDVHYEWFRNSDRLLKSDKI----EIKKKRLHIKNVGPS-DN 185 Query: 902 GDYKCVASNSAGK--SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK 959 G Y+C+A+N+AG S+ + + E+ ++ + + +G T +CQ T+ Sbjct: 186 GVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTE 245 Query: 960 WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI-VKDQETSTMLVVKETIPE 1018 WY KK+ +++ + D G C+ ++ + T E Sbjct: 246 WYF-KKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCVGIRSEST-------EIPQS 297 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDG---------EIIKPKK------NKY 1063 +I +L+ + E V E ++ + VV G + + P K + Sbjct: 298 YIAELKLAYLSEFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGH 357 Query: 1064 DFEKRGHIR----KLYIRNTSVHDEGEYSCILRDESCTAE--VTVVELPPEIITRLQ--- 1114 G +R +L I + G Y+C+ + + E + +V L ++T Sbjct: 358 TVSDSGEVRVDDGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSV 417 Query: 1115 NQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS------NHIQLTIDGKKQKLKIYDC 1168 N+ + T + E +V+W KDG ++ + ++ I L I + Sbjct: 418 TVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRET 477 Query: 1169 DLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL--TVEIPDETLD 1226 + D GEY CEV +L+ EP+ + +F+ P N L ++ + Sbjct: 478 ESHDRGEYVCEVLAKGFEPVLS--EPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQG 535 Query: 1227 -----VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKL 1279 +TW K + E + +IS TL+ +D+ +YTCV +++ + Sbjct: 536 TPPPIITWEK---LGESFDNSRIIS--MNGTLVFNGVLNEDKGKYTCVATNSQGVINVTI 590 Query: 1280 KVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 ++VV P V+ + + G VT+ + P+P W N K + H++ ++ Sbjct: 591 NIDVVVAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLK-MNDFDHSRFTV- 648 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCG--HADVEMNVTILDKPSPPGKPNI 1389 ++ +L I +V D Y N+ G +V++ V D P G + Sbjct: 649 LENGTLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHSRDGYHPDGDSTV 700 Score = 70.5 bits (165), Expect = 5e-10 Identities = 152/707 (21%), Positives = 267/707 (37%), Gaps = 88/707 (12%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV-ATL 568 P F E R G +V C+V P +T++ + K + + + N+ T Sbjct: 23 PYFSESPRNVDVVQGKSVTLPCKVT--PGIGMTYYWELNGSKIANTTRRHQQGSNLHITR 80 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 V RE D+G FTC+A++ ST+ L S SE ++ Sbjct: 81 VDRE---RDSGQFTCIAED------STSSLAG----SIRSSEASLNIQW----------- 116 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 ++ + + A ++ GSD+ L C A + W + ++ + I + + Sbjct: 117 IDEVSVQLQEPESASFISRGSDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEIKKKR-- 174 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 L I NV G Y +A N G + +E + + +V Q Sbjct: 175 ------LHIKNVGPSDNGVYRCLANNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQ 228 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYT-- 804 G + Q + +T K + L HS L+ V KD+G Y+ Sbjct: 229 GGTAYFDCQY---QQAEVTEWYFKKDTRPLENGKKFVIHSNGTLQINDVQGKDQGFYSCV 285 Query: 805 -LKAENSE----GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 +++E++E IAE + + E T + EPPL N ++ E G +L + Sbjct: 286 GIRSESTEIPQSYIAELK-LAYLSEFTVNSFEPPLSENS-NQVVAPEGGLFQLTCLEPDS 343 Query: 860 PVPSITWYRN--NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P+ W+ N +S S + + DG L+I V + +G+Y CVA N AGK+ Sbjct: 344 LPPAKKWWLNTGGHTVSDSGEVRVD-DG---RLIIEKVRMD-HAGNYTCVAENMAGKTEK 398 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ---TSHTVSTKWYHNKKEI------S 968 + + + V + L S +E + +L C +H KW + K + + Sbjct: 399 IIELVVLNKPVVTAQPL--SVTVDENEPSMLTCDYEPKNHFTIVKWRKDGKSLRHDFGEN 456 Query: 969 GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIP-----EFIRKL 1023 +D + I D G C V + +L TI +F+ Sbjct: 457 SLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLAKGFEPVLSEPATISVIEKLKFVPPP 516 Query: 1024 QDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 + +++ VA + + ++ WE+ GE N G L Sbjct: 517 VNKKLELGSVAKVHCKAQGTPPPIITWEKLGESF---DNSRIISMNG---TLVFNGVLNE 570 Query: 1083 DEGEYSCILRDESCTAEVTV---VELPPEIITRLQN-QKVNKGNKATFEIELTKGD--AL 1136 D+G+Y+C+ + VT+ V + P+ +N +V +G T + + +GD Sbjct: 571 DKGKYTCVATNSQGVINVTINIDVVVAPKFSVEPKNPTEVTEGQSVTIDC-VVEGDPKPT 629 Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 + W K+ F +H + T+ + L I + +D +Y C GNS Sbjct: 630 IHWDKNLKMNDF-DHSRFTV-LENGTLFISEVHREDENKYGCTAGNS 674 Score = 66.1 bits (154), Expect = 1e-08 Identities = 136/618 (22%), Positives = 245/618 (39%), Gaps = 69/618 (11%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 E P F + + V + ++ L +VT + W N I+ T ++ G N+ Sbjct: 21 EDPYFSESPRNVDVVQGKSVTLPCKVTPGIGMTYYWELNGSKIA--NTTRRHQQGSNLH- 77 Query: 891 VITNVDSEIDSGDYKCVASNSAGK---SSHGARVTIDVEKVTFVK-HLQKSYET---EEG 943 IT VD E DSG + C+A +S S + +++++ + V LQ+ G Sbjct: 78 -ITRVDRERDSGQFTCIAEDSTSSLAGSIRSSEASLNIQWIDEVSVQLQEPESASFISRG 136 Query: 944 KTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 V L C T S V +W+ N + D EI + D GV +C+ Sbjct: 137 SDVTLRCHTDASGDVHYEWFRNSDRLLKSDKIEI----KKKRLHIKNVGPSDNGVYRCLA 192 Query: 1002 KD------QETSTMLVVKETIPEFIRKL-QDFEVKEKDVAILEVEI-NSETADVVWERDG 1053 + T+ L V I+ + +D V + A + + +E + +++D Sbjct: 193 NNTAGARYSTTNFALAVAGEETALIQVVPRDQLVPQGGTAYFDCQYQQAEVTEWYFKKDT 252 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI-LRDESC------TAEVTVVELP 1106 ++ K K+ G L I + D+G YSC+ +R ES AE+ + L Sbjct: 253 RPLENGK-KFVIHSNG---TLQINDVQGKDQGFYSCVGIRSESTEIPQSYIAELKLAYLS 308 Query: 1107 PEIITRLQNQKVNKGNKAT------FEIELTKGDAL---VRWFKDGSEIQFSNHIQLTID 1157 + + N+ F++ + D+L +W+ + S+ ++ +D Sbjct: 309 EFTVNSFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVRVD 368 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 +L I +D AG Y+C N K I+ + + P + V N + Sbjct: 369 --DGRLIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSVTVDENEPSM 426 Query: 1216 LTVEI-PDETLDVTWYKK--KSVIEDTEKFTL----ISDVK-KRTLIIRKCTEDDQCEYT 1267 LT + P + ++K KS+ D + +L I K +L+IR+ D+ EY Sbjct: 427 LTCDYEPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYV 486 Query: 1268 CVLL----DAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 C +L + + + V+E K V +++ GS + Q P P W Sbjct: 487 CEVLAKGFEPVLSEPATISVIE-KLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITW-- 543 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 K+ + +++ I S + +L V N D G Y N+ G +V +N+ ++ P Sbjct: 544 -EKLGESFDNSR--IISMNGTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAPKF 600 Query: 1384 PGKP-NILEI-DSSSINI 1399 +P N E+ + S+ I Sbjct: 601 SVEPKNPTEVTEGQSVTI 618 Score = 57.2 bits (132), Expect = 5e-06 Identities = 50/185 (27%), Positives = 76/185 (41%), Gaps = 17/185 (9%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L+ +PP +KK ++ GS + C+ P P I W GE IS+ Sbjct: 510 LKFVPPPVNKK-----LELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRIISMN----- 559 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 L V +G YT VA N +G ++ I + + P +EP V + Sbjct: 560 ----GTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVA---PKFSVEPKNPTEVTE 612 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAE 808 G+SV + V G+P+PTI W KN K ++ + + +DE Y A Sbjct: 613 GQSVTIDCVVEGDPKPTIHWDKNLKMNDFDHSRFTVLENGTLFISEVHREDENKYGCTAG 672 Query: 809 NSEGI 813 NS G+ Sbjct: 673 NSAGL 677 Score = 53.6 bits (123), Expect = 6e-05 Identities = 78/322 (24%), Positives = 117/322 (36%), Gaps = 23/322 (7%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 LI+E DH T +++ P + +P + VDE +L C Sbjct: 372 LIIEKVRMDHAGNYTCVAENMAGKTEKIIELVVLNKPVVTAQPLSVTVDENEPSMLTCDY 431 Query: 658 VAIPEPDIA-WLFKGEEIVPD--ENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714 I W G+ + D EN + + + L I + G Y + Sbjct: 432 EPKNHFTIVKWRKDGKSLRHDFGENSLDRQRIKIFKHNASLVIRETESHDRGEYVCEVLA 491 Query: 715 REGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKP 774 + E L I EK + + P + + G + + G P P ITW K + Sbjct: 492 KGFEPVLSEPATISVIEKL--KFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGES 549 Query: 775 VKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPL 834 S T + +D+G YT A NS+G+ + I V + + EP Sbjct: 550 FDNSRIISMNGT---LVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAPKFSVEP-- 604 Query: 835 FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN---NEIISPSETITQNFDGENIELV 891 E+T + TI V V +P P+I W +N N+ T+ EN L Sbjct: 605 --KNPTEVTEGQSVTIDCV--VEGDPKPTIHWDKNLKMNDFDHSRFTVL-----ENGTLF 655 Query: 892 ITNVDSEIDSGDYKCVASNSAG 913 I+ V E D Y C A NSAG Sbjct: 656 ISEVHRE-DENKYGCTAGNSAG 676 Score = 51.2 bits (117), Expect = 3e-04 Identities = 33/96 (34%), Positives = 46/96 (47%), Gaps = 4/96 (4%) Query: 508 MAPIF-VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +AP F VE P +G +V +C VEG P+P I W + + D + +N Sbjct: 596 VAPKFSVEPKNPTEVTEGQSVTIDCVVEGDPKPTIHWDKNLKM--NDFDHSRFTVLEN-G 652 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 TL I EV ED + C A N+AG +LIV + Sbjct: 653 TLFISEVHREDENKYGCTAGNSAGLNRQEVQLIVHS 688 Score = 45.2 bits (102), Expect = 0.020 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 7/109 (6%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555 PV +P + FV K GS + C+ +G P P ITW + S+ Sbjct: 496 PVLSEPATISVIEKLKFVPPPVNKKLELGSVAKVHCKAQGTPPPIITWEKLGESFDNSRI 555 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 M TLV V ED G +TCVA N+ G + T + +V AP Sbjct: 556 ISMN------GTLVFNGVLNEDKGKYTCVATNSQGVINVTINIDVVVAP 598 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/94 (29%), Positives = 38/94 (40%), Gaps = 3/94 (3%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S P E P+G Q C P W+ T S ++ DD Sbjct: 314 SFEPPLSENSNQVVAPEGGLFQLTCLEPDSLPPAKKWWLNTGGHTVSDSGEVRVDDGR-- 371 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L+I +V + AG +TCVA+N AG EL+V Sbjct: 372 -LIIEKVRMDHAGNYTCVAENMAGKTEKIIELVV 404 >UniRef50_Q9VQ08 Cluster: CG5481-PA; n=6; Diptera|Rep: CG5481-PA - Drosophila melanogaster (Fruit fly) Length = 1463 Score = 103 bits (247), Expect = 5e-20 Identities = 96/381 (25%), Positives = 153/381 (40%), Gaps = 29/381 (7%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLV 658 I EA SD G V A + + P + P+ Q GS ++ +CR+ Sbjct: 248 IQEARQSDDGRYQCVVKNVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIG 307 Query: 659 AIPEPDIAWLFKGE-EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P PD+ W +P + V + LK+ +V G YT A N G Sbjct: 308 GDPLPDVLWRRTASGGNMPLRRVHVLEDRS-------LKLDDVTLEDMGEYTCEADNAVG 360 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 + +L + PP+ + K+ +V G+ V+ Q G+PRPT+ W Sbjct: 361 GITATGILTVHA----PPKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLL 416 Query: 778 LPTKSDG--------DTHSITILKPKKVKDEG-VYTLKAENSEGIAETSAVITVEEPTEE 828 LP DG + S+ + +D G V T A N+ G + V++V+ T+ Sbjct: 417 LPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVD--TQF 474 Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENI 888 PP+ T+ K + L R PVP ++WY + I E +N Sbjct: 475 ELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAG- 533 Query: 889 ELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ----KSYETEEGK 944 L I+++ D G Y CVASN GKSS + +D +K + +Y GK Sbjct: 534 ALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGK 593 Query: 945 TVILECQTSHTVSTKWYHNKK 965 ++E + ++V+ W + K Sbjct: 594 PQMVE-KGENSVTLSWTRSNK 613 Score = 92.7 bits (220), Expect = 1e-16 Identities = 142/578 (24%), Positives = 234/578 (40%), Gaps = 69/578 (11%) Query: 949 ECQTSHTVSTKWYHNKKEISGM--DHREIIQEGRXXXXXXXXXXX-XDVGVIKCIVKDQ- 1004 + + + T + +W+ + +E+ HR ++ G D G C K++ Sbjct: 113 QAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFLKVIHSRRESDAGTYWCEAKNEF 172 Query: 1005 ----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI--NSETADVVWERDGEIIKP 1058 + L V EF + + V + +VA++E S + W ++G+ + Sbjct: 173 GVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNL 232 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD-----ESCTAEVTVVELPPEIITRL 1113 NK G L I+ D+G Y C++++ ES TA + V + P +I Sbjct: 233 VGNKRIRIVDGG--NLAIQEARQSDDGRYQCVVKNVVGTRESATAFLKV-HVRPFLIRGP 289 Query: 1114 QNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 QNQ G+ F+ + GD L V W + S ++ + LK+ D L+ Sbjct: 290 QNQTAVVGSSVVFQCRIG-GDPLPDVLWRRTASGGNMPLRRVHVLEDRS--LKLDDVTLE 346 Query: 1172 DAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDET 1224 D GEY+CE VG T ILTV P F +R P+ LV + + P T Sbjct: 347 DMGEYTCEADNAVGGITATGILTVHAPP-KFVIR-PKNQLVEIGDEVLFECQANGHPRPT 404 Query: 1225 LDVTWYKKKSVI-----EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA----KS 1275 L + S++ + + TL + + I R ED TC L+A S Sbjct: 405 LYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSIARFAREDSGKVVTCNALNAVGSVSS 464 Query: 1276 TTKLKVEV-VEFPPKIVDY-EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 T + V+ E PP I++ + S V L P P W ++ I +H Sbjct: 465 RTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEH 524 Query: 1334 TKPSIDSKSASLTIKKVE-NTDAGIYKLRLENNCGHA--------DVEMNVTI------- 1377 + ++ S + +LTI ++ + D G+Y N G + D N I Sbjct: 525 ERRNL-SDAGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDTPTNPNIKFFRAPE 583 Query: 1378 -LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE-YQEIDTTEWIS----VK 1431 P PPGKP ++E +S+ + W G S+++ YV+E + + +T W++ V+ Sbjct: 584 LSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQ 643 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 N T TQT L +Y F A N +S S +E Sbjct: 644 NTTFTQT---GLLPGVNYFFLIRAENSHGLSLPSPMSE 678 Score = 60.5 bits (140), Expect = 5e-07 Identities = 75/330 (22%), Positives = 130/330 (39%), Gaps = 22/330 (6%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE-NISVAIESD 687 L+G P + P V + C+ P P I W G E+ D + + + + Sbjct: 86 LKGENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAG 145 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + V I + ++ GTY A N G A S L++ E +EP + V Sbjct: 146 GLFFLKV--IHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDE--FRLEPANTR-V 200 Query: 747 RQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDG--DTHSITILKPKKVKDEGVY 803 QGE ++ G+P P I+W KN + + + K D ++ I + ++ D+G Y Sbjct: 201 AQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQ-SDDGRY 259 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 +N G E++ P I Q T ++ R+ +P+P Sbjct: 260 QCVVKNVVGTRESATAFLKVHVR------PFLIRGPQNQTAVVGSSVVFQCRIGGDPLPD 313 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W R + + + E+ L + +V E D G+Y C A N+ G + +T+ Sbjct: 314 VLWRRTAS--GGNMPLRRVHVLEDRSLKLDDVTLE-DMGEYTCEADNAVGGITATGILTV 370 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTS 953 ++ K+ E G V+ ECQ + Sbjct: 371 HAPPKFVIR--PKNQLVEIGDEVLFECQAN 398 Score = 58.4 bits (135), Expect = 2e-06 Identities = 70/316 (22%), Positives = 128/316 (40%), Gaps = 25/316 (7%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF---DGEN 887 E P I + TV + + NP P+I W+++ + ++T + G Sbjct: 89 ENPRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELK-TDTGSHRIMLPAGGL 147 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY-ETEEGKTV 946 L + + E D+G Y C A N G + T+ V + L+ + +G+ Sbjct: 148 FFLKVIHSRRESDAGTYWCEAKNEFGVA-RSRNATLQVAFLRDEFRLEPANTRVAQGEVA 206 Query: 947 ILEC---QTSHTVSTKWYHNKKEISGMDHREI-IQEGRXXXXXXXXXXXXDVGVIKCIVK 1002 ++EC + S W N + ++ + ++ I I +G D G +C+VK Sbjct: 207 LMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDG--GNLAIQEARQSDDGRYQCVVK 264 Query: 1003 D----QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETA-DVVWERDGEIIK 1057 + +E++T + P IR Q+ + + I + DV+W R Sbjct: 265 NVVGTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLWRRTASGGN 324 Query: 1058 -PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE--SCTAE-VTVVELPPEIITRL 1113 P + + E R L + + ++ D GEY+C + TA + V PP+ + R Sbjct: 325 MPLRRVHVLEDRS----LKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRP 380 Query: 1114 QNQKVNKGNKATFEIE 1129 +NQ V G++ FE + Sbjct: 381 KNQLVEIGDEVLFECQ 396 Score = 58.0 bits (134), Expect = 3e-06 Identities = 62/227 (27%), Positives = 99/227 (43%), Gaps = 37/227 (16%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPS-QD--FQMYYDDDN 564 P FV + + + G V FECQ G+PRP + W + ++++ P +D ++ + Sbjct: 374 PKFVIRPKNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEG 433 Query: 565 VATLVIREVFPEDAG-TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXX 623 + L I ED+G TC A NA G SS T + V+ Sbjct: 434 RSVLSIARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQ-------------------- 473 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 E PP + P Q + S ++L CR + P P ++W G I E+ Sbjct: 474 -----FELPPPIIEQGPVNQTLPVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRN 528 Query: 684 IESDMHMYCSVLKITNVKKFQ-EGTYTVVAVNREGEASLPIVLKIKT 729 + SD L I+++++ + EG YT VA NR G++S L++ T Sbjct: 529 L-SD----AGALTISDLQRHEDEGLYTCVASNRNGKSSWSGYLRLDT 570 Score = 56.4 bits (130), Expect = 8e-06 Identities = 80/310 (25%), Positives = 113/310 (36%), Gaps = 42/310 (13%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTW------------YRDGKKLKTAKATYENRXXXX 1536 KN E +++ C G P+P + W YRDG+ T T E R Sbjct: 381 KNQLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTL--TPEGRSVLS 438 Query: 1537 XXXXXXXXXXXY-KCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLV 1592 C A N G V + VV + + P I + Q V ++ Sbjct: 439 IARFAREDSGKVVTCNALNAVGSVSSRTVVSVDTQFELPPPIIEQGPVNQTLPVKSIVVL 498 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKR-SHSSKYTIEASNTA 1651 G P P+V WY +G ++ +E+ + I +L+R YT ASN Sbjct: 499 PCRTLGTPVPQVSWYLDGIPID-VQEHERRNLSDAGALTISDLQRHEDEGLYTCVASNRN 557 Query: 1652 GTSS----------VEVTLKVYDKPS-----KPEGPVIMREISRESVTIEWKPPLDDGGL 1696 G SS +K + P P G M E SVT+ W GG Sbjct: 558 GKSSWSGYLRLDTPTNPNIKFFRAPELSTYPGPPGKPQMVEKGENSVTLSWTRSNKVGGS 617 Query: 1697 ELTKYAIE---KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS-EA 1752 L Y IE K+E D W+ V ++ T+ L Y F + A+N G S + Sbjct: 618 SLVGYVIEMFGKNETDG--WVAVGTRVQNT-TFTQTGLLPGVNYFFLIRAENSHGLSLPS 674 Query: 1753 LESEPIVIKT 1762 SEPI + T Sbjct: 675 PMSEPITVGT 684 Score = 55.6 bits (128), Expect = 1e-05 Identities = 77/332 (23%), Positives = 120/332 (36%), Gaps = 26/332 (7%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDF--EKRGHIRK 1073 P I D V + D + T + W +DG +K + G Sbjct: 91 PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150 Query: 1074 LYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 I + D G Y C ++E S A + V L E N +V +G A E Sbjct: 151 KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQGEVALMEC 210 Query: 1129 ELTKG--DALVRWFKDGSEIQFSNHIQLTI-DGKKQKLKIYDCDLDDAGEYSCEVGN--- 1182 +G + + W K+G + + ++ I DG L I + D G Y C V N Sbjct: 211 GAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGN--LAIQEARQSDDGRYQCVVKNVVG 268 Query: 1183 --SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDT 1239 TA L V F +R P+ + I + L DV W +++ Sbjct: 269 TRESATAFLKVHVRP--FLIRGPQNQTAVVGSSVVFQCRIGGDPLPDVLW--RRTASGGN 324 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS-TTKLKVEVVEFPPKIVDYEREYR 1298 + ++ R+L + T +D EYTC +A T + V PPK V + Sbjct: 325 MPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPKNQL 384 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIV--NSKII 1328 ++ G +V P+P W V NS ++ Sbjct: 385 VEIGDEVLFECQANGHPRPTLYWSVEGNSSLL 416 Score = 49.2 bits (112), Expect = 0.001 Identities = 50/216 (23%), Positives = 83/216 (38%), Gaps = 19/216 (8%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX----- 1538 +E P+ + T N+ C G P P + W++DG++LKT ++ Sbjct: 94 IEHPM-DTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFLKV 152 Query: 1539 --XXXXXXXXXYKCIAFNDHGEVE----TSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C A N+ G T V ++ + + +N + Q G+ L+ Sbjct: 153 IHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRDEFRLEPANTRVAQ----GEVALM 208 Query: 1593 TA-VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 G P P++ W KNG L I + + + I+E ++S +Y N Sbjct: 209 ECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGN-LAIQEARQSDDGRYQCVVKNVV 267 Query: 1652 GT-SSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 GT S LKV+ +P GP + SV + Sbjct: 268 GTRESATAFLKVHVRPFLIRGPQNQTAVVGSSVVFQ 303 Score = 48.8 bits (111), Expect = 0.002 Identities = 75/391 (19%), Positives = 137/391 (35%), Gaps = 27/391 (6%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P+I+++ + + + T + P P +W + + +K + + + Sbjct: 91 PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150 Query: 1348 KKVEN---TDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 K + + +DAG Y +N G A + + V L + +P + + + Sbjct: 151 KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFL-RDEFRLEPANTRVAQGEVALME 209 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 I + Q ++ ++ + +IQ + + R++ N V Sbjct: 210 CGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGT 269 Query: 1462 SDASETTEYYKV-IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR--D 1518 +++ T + KV ++ I+ P +N T + C GG P P V W R Sbjct: 270 RESA--TAFLKVHVRPFLIRGP------QNQTAVVGSSVVFQCRIGGDPLPDVLWRRTAS 321 Query: 1519 GKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNE 1578 G + + Y C A N G + + ++ + P I + Sbjct: 322 GGNMPLRRVHVLEDRSLKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPPKFVIRPK 381 Query: 1579 DIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL-----ENDKEYNIT-TKEKTSVIRI 1632 + Q ++GDE L G P P + W GN D +T T E SV+ I Sbjct: 382 N--QLVEIGDEVLFECQANGHPRPTLYWSVEGNSSLLLPGYRDGRMEVTLTPEGRSVLSI 439 Query: 1633 KELKRSHSSK-YTIEASNTAGTSSVEVTLKV 1662 R S K T A N G+ S + V Sbjct: 440 ARFAREDSGKVVTCNALNAVGSVSSRTVVSV 470 Score = 47.6 bits (108), Expect = 0.004 Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 3/80 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS+V F+C++ G P P + W R+TA +++ +D +L + +V ED G +TC Sbjct: 297 GSSVVFQCRIGGDPLPDVLW-RRTASGGNMPLRRVHVLEDR--SLKLDDVTLEDMGEYTC 353 Query: 584 VAKNAAGFASSTTELIVEAP 603 A NA G ++T L V AP Sbjct: 354 EADNAVGGITATGILTVHAP 373 Score = 46.4 bits (105), Expect = 0.009 Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 3/105 (2%) Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-MWMEV 2016 R + +T P PP P + G N V SW GG+ L+GY I + +T W+ V Sbjct: 580 RAPELSTYPGPPGKPQMVEK-GENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAV 638 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 G NT F L Y I A N GLS P EP V Sbjct: 639 GTRVQNT-TFTQTGLLPGVNYFFLIRAENSHGLSLPSPMSEPITV 682 Score = 44.4 bits (100), Expect = 0.035 Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 2/99 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATL 568 P +E P F CQ EG P P I WF+ +K + ++ + L Sbjct: 91 PRIIEHPMDTTVPKNDPFTFNCQAEGNPTPTIQWFKDGRELKTDTGSHRIMLPAGGLFFL 150 Query: 569 -VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 VI DAGT+ C AKN G A S + A L D Sbjct: 151 KVIHSRRESDAGTYWCEAKNEFGVARSRNATLQVAFLRD 189 Score = 41.1 bits (92), Expect = 0.33 Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 9/91 (9%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923 PP +P+ + E SVTL WT GGS + Y+IE F + W V VG V Sbjct: 590 PPGKPQ---MVEKGENSVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGW---VAVGTRVQ 643 Query: 1924 EHCI--ENIKEKDEIIFRISAENTVGVSLPT 1952 + F I AEN+ G+SLP+ Sbjct: 644 NTTFTQTGLLPGVNYFFLIRAENSHGLSLPS 674 Score = 40.3 bits (90), Expect = 0.57 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 3/81 (3%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWKXXXXXXXXXARIQK-LSINTTYQFRI 1839 SV ++W S K GGS ++ Y +E+ K E W Q L Y F I Sbjct: 603 SVTLSWTRSNKVGGSSLVGYVIEMFGKNETDGWVAVGTRVQNTTFTQTGLLPGVNYFFLI 662 Query: 1840 YARNEIGTSLPYTSDDKITIG 1860 A N G SLP + IT+G Sbjct: 663 RAENSHGLSLPSPMSEPITVG 683 Score = 38.3 bits (85), Expect = 2.3 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 1/82 (1%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P S V C+ G P PQ++W+ I + + D T+ + ED G + Sbjct: 491 PVKSIVVLPCRTLGTPVPQVSWYLDGIPIDVQEHERRNLSDAGALTISDLQRH-EDEGLY 549 Query: 582 TCVAKNAAGFASSTTELIVEAP 603 TCVA N G +S + L ++ P Sbjct: 550 TCVASNRNGKSSWSGYLRLDTP 571 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 5/88 (5%) Query: 515 KLRPKHT--PDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIR 571 +L P +T G EC G P PQI+W + + + ++ D L I+ Sbjct: 192 RLEPANTRVAQGEVALMECGAPRGSPEPQISWRKNGQTLNLVGNKRIRIVDGG--NLAIQ 249 Query: 572 EVFPEDAGTFTCVAKNAAGFASSTTELI 599 E D G + CV KN G S T + Sbjct: 250 EARQSDDGRYQCVVKNVVGTRESATAFL 277 Score = 36.3 bits (80), Expect = 9.2 Identities = 33/164 (20%), Positives = 66/164 (40%), Gaps = 8/164 (4%) Query: 1507 GVPQPKVTWYRDGKKLK---TAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-S 1562 G P+P+++W ++G+ L + + Y+C+ N G E+ + Sbjct: 215 GSPEPQISWRKNGQTLNLVGNKRIRIVDGGNLAIQEARQSDDGRYQCVVKNVVGTRESAT 274 Query: 1563 CVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNIT 1622 + + +P + ++ Q VG + I G P P+V+W + + N + Sbjct: 275 AFLKVHVRPFLIRGPQN--QTAVVGSSVVFQCRIGGDPLPDVLWRRTASG-GNMPLRRVH 331 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 E S +++ ++ +YT EA N G + L V+ P Sbjct: 332 VLEDRS-LKLDDVTLEDMGEYTCEADNAVGGITATGILTVHAPP 374 >UniRef50_Q15772 Cluster: Striated muscle preferentially expressed protein kinase; n=26; Theria|Rep: Striated muscle preferentially expressed protein kinase - Homo sapiens (Human) Length = 3223 Score = 103 bits (247), Expect = 5e-20 Identities = 112/449 (24%), Positives = 185/449 (41%), Gaps = 38/449 (8%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 EE AP+F L+ G+ V +C + P PQ++W + + ++ S+ + + Sbjct: 716 EEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALR-SEGRLLLRAEG 774 Query: 564 NVATLVIREVFPEDAGTF-----------TCVAK-------NAAGFASSTT---ELIV-- 600 TL++RE DAG++ TC A + + F+S T E + Sbjct: 775 ERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPP 834 Query: 601 -EAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVA 659 E P T +D PPTF Q V EG D+++ R+ Sbjct: 835 EEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQG 894 Query: 660 IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEA 719 P+P ++WL + + PD+ A E++ + C L+I ++ G YT AVN G Sbjct: 895 EPKPVVSWLRNRQPVRPDQR-RFAEEAEGGL-CR-LRILAAERGDAGFYTCKAVNEYGAR 951 Query: 720 SLPIVLKIKT-GEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKPVKA 777 L+++ E V+ PL+ + V GE + V G + W C+ A Sbjct: 952 QCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA 1011 Query: 778 -LPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 L K D +L +D+ GVYT K ++ SA +TV + PLF Sbjct: 1012 LLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRP-----SLAPLF 1066 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 +++ V E + +++ P P +TW + SE + DG L I +V Sbjct: 1067 TRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHV 1126 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTID 924 SE D G Y A N+ G++ A++ ++ Sbjct: 1127 GSE-DEGLYAVSAVNTHGQAHCSAQLYVE 1154 Score = 91.9 bits (218), Expect = 2e-16 Identities = 69/259 (26%), Positives = 115/259 (44%), Gaps = 13/259 (5%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDG 784 TG K PP L VR+G+ VI+S +V G P+P ++W +N +PV + +++G Sbjct: 863 TGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEG 922 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 + IL ++ D G YT KA N G + A + V E + L Q++ V Sbjct: 923 GLCRLRILAAER-GDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVL--APLQDVDV 979 Query: 845 KEKGTIKLVARVTRNPVP-SITWYRNNEIISPS-ETITQNFDGENIELVITNVDSEIDSG 902 G + L + P + W ++ P+ +FDG +L++T+V E DSG Sbjct: 980 -GAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSV-HEDDSG 1037 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS--TKW 960 Y C S + + + AR+T+ L + E EG+ +C+ S T W Sbjct: 1038 VYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTW 1097 Query: 961 YHNKKEISGMDHREIIQEG 979 H + ++ + Q+G Sbjct: 1098 THFGCPMEESENLRLRQDG 1116 Score = 75.4 bits (177), Expect = 2e-11 Identities = 61/250 (24%), Positives = 102/250 (40%), Gaps = 7/250 (2%) Query: 487 KLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 KL+ D+L + T S+AP+F L +G +F+C++ G P P +TW Sbjct: 1042 KLSTAKDELTCSARLTVRP-SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHF 1100 Query: 547 TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 ++ S++ ++ D + +L I V ED G + A N G A + +L VE P + Sbjct: 1101 GCPMEESENLRL-RQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTA 1159 Query: 607 HGSEMTVXXXXXXXXXXXXADILEGIP-PTFSKKPKAQYVDEGSDILLECRLVAIPEPDI 665 + LE + P F + + V + +LEC++ +P P I Sbjct: 1160 ASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTI 1219 Query: 666 AWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 +W G I ++ + D+H L V G Y V N+ G+A+ L Sbjct: 1220 SWFHNGHRIQSSDDRRMTQYRDVHR----LVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1275 Query: 726 KIKTGEKEPP 735 + PP Sbjct: 1276 YVTDVVPGPP 1285 Score = 73.7 bits (173), Expect = 5e-11 Identities = 75/302 (24%), Positives = 122/302 (40%), Gaps = 40/302 (13%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVK 701 V G L EC + + ++ WL +G + P ++ MH C +L +T+V Sbjct: 979 VGAGEMALFECLVAGPTDVEVDWLCRGRLLQP-----ALLKCKMHFDGRKCKLL-LTSVH 1032 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 + G YT + E + L ++ P L+ + V +G + ++ G Sbjct: 1033 EDDSGVYTCKLSTAKDELTCSARLTVRPSLA--PLFTRLLEDVEVLEGRAARFDCKISGT 1090 Query: 762 PRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 P P +TW P++ L + DG HS+ I +DEG+Y + A N+ G A SA Sbjct: 1091 PPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGS-EDEGLYAVSAVNTHGQAHCSA 1149 Query: 819 VITVEEPTEENAEP------------------------PLFINRFQEITVKEKGTIKLVA 854 + VEEP + P P F+ Q++ V L Sbjct: 1150 QLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLEC 1209 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 +VT P P+I+W+ N I S+ + LV V + +G YK V +N GK Sbjct: 1210 QVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQ-HAGVYKSVIANKLGK 1268 Query: 915 SS 916 ++ Sbjct: 1269 AA 1270 Score = 73.7 bits (173), Expect = 5e-11 Identities = 74/371 (19%), Positives = 137/371 (36%), Gaps = 18/371 (4%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMN 1374 P P W N I+ + + L V AG+YK + N G A + Sbjct: 1215 PYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAH 1274 Query: 1375 VTILDK-PSPP-GKPNILEIDSSSINICWDEPENTG---NSTIIYYVVEYQEIDTTEWIS 1429 + + D P PP G P ++ + + + W+ P + + + Y V++Q + + +W + Sbjct: 1275 LYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTA 1334 Query: 1430 -VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE--TKIQSPTVEK 1486 V + + + L+ + FR + S S +E ++++ T ++P + Sbjct: 1335 LVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLD 1394 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAKATYE------NRXXXXXXX 1539 + + +T F V + +V W G L+ YE ++ Sbjct: 1395 KPDIVYVVEGQPASVTVTFNHV-EAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICR 1453 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 C A N HG S + + + P ED++ G+ V+EG Sbjct: 1454 VSRRDMGALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVG--AGETARFAVVVEGK 1511 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P+++WYK+ L + +E + + YT A N AG S + Sbjct: 1512 PLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAE 1571 Query: 1660 LKVYDKPSKPE 1670 L V+ + E Sbjct: 1572 LAVHSAQTAME 1582 Score = 70.1 bits (164), Expect = 6e-10 Identities = 73/267 (27%), Positives = 112/267 (41%), Gaps = 18/267 (6%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F L D V+E I+ + + E VV W R+ + ++P + ++ E G + +L Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928 Query: 1076 IRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE----IITRLQNQKVNKGNKATFE 1127 I D G Y+C +E C A + V P ++ LQ+ V G A FE Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFE 988 Query: 1128 IELTKG--DALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 L G D V W G +Q + ++ DG+K KL + DD+G Y+C++ +K Sbjct: 989 C-LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAK 1047 Query: 1185 ----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIEDT 1239 C+A LTV RL E + V A +I VTW +E++ Sbjct: 1048 DELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEES 1107 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEY 1266 E L D +L I +D+ Y Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLY 1134 Score = 60.1 bits (139), Expect = 7e-07 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E + AP F + G T +F VEG P P I W++ ++ S Y ++N Sbjct: 1480 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVY-EEN 1538 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 +LV+ +D G +TC A+N AG S EL V + Sbjct: 1539 ECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHS 1576 Score = 58.0 bits (134), Expect = 3e-06 Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 16/156 (10%) Query: 780 TKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF 839 ++ D D + + I + + +D G T A N G +T +V T E AE P F + Sbjct: 1440 SQPDDDQYCLRICRVSR-RDMGALTCTARNRHG-TQTCSV------TLELAEAPRFESIM 1491 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 +++ V T + V P+P I WY++ +++ S ++ ++ LV+ + ++ Sbjct: 1492 EDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQ- 1550 Query: 900 DSGDYKCVASNSAGKSS-------HGARVTIDVEKV 928 D G Y C A N AG+ S H A+ ++VE V Sbjct: 1551 DGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGV 1586 Score = 51.6 bits (118), Expect = 2e-04 Identities = 29/101 (28%), Positives = 54/101 (53%), Gaps = 6/101 (5%) Query: 727 IKTGEK--EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTK 781 + GE+ E P PL++++V G V+L + NP P ++W K+ +++ L + Sbjct: 712 VSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLR 771 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 ++G+ H++ +L+ + D G Y A N G A +A +TV Sbjct: 772 AEGERHTL-LLREARAADAGSYMATATNELGQATCAASLTV 811 Score = 50.4 bits (115), Expect = 5e-04 Identities = 36/175 (20%), Positives = 78/175 (44%), Gaps = 6/175 (3%) Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 E ++ + G+P P + W+ NG+++++ + +T + + H+ Y + Sbjct: 1204 EAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIA 1263 Query: 1649 NTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPP--LDDG-GLELTKYAIE 1704 N G ++ L V D P P+G + ++ VT+ W PP LD + Y ++ Sbjct: 1264 NKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQ 1323 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758 +++W + R+ + L + +++FRV++ S+ + SEP+ Sbjct: 1324 HQVLGSDQWTALVTGLRE-PGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPV 1377 Score = 49.2 bits (112), Expect = 0.001 Identities = 19/62 (30%), Positives = 34/62 (54%) Query: 1463 DASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + + + Y E +++P E PL+N+ P D+ L CI P P+V+W++DG L Sbjct: 703 ELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSAL 762 Query: 1523 KT 1524 ++ Sbjct: 763 RS 764 Score = 49.2 bits (112), Expect = 0.001 Identities = 64/280 (22%), Positives = 102/280 (36%), Gaps = 19/280 (6%) Query: 552 PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEM 611 P + M D D++ V +V D T G+A++ V+ + Sbjct: 1305 PPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLST-- 1362 Query: 612 TVXXXXXXXXXXXXADILEGIP-----PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIA 666 TV +LE P P KP YV EG + + E + Sbjct: 1363 TVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHV-EAQVV 1421 Query: 667 WLF-KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVL 725 W +G + + + D YC L+I V + G T A NR G + + L Sbjct: 1422 WRSCRGALLEARAGVYELSQPDDDQYC--LRICRVSRRDMGALTCTARNRHGTQTCSVTL 1479 Query: 726 KIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKS--- 782 ++ E P+ ++ + V GE+ + V G P P I W K+ + S Sbjct: 1480 ELA----EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVY 1535 Query: 783 DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + + S+ +L +D GVYT A+N G A + V Sbjct: 1536 EENECSLVVLS-TGAQDGGVYTCTAQNLAGEVSCKAELAV 1574 Score = 48.8 bits (111), Expect = 0.002 Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 10/177 (5%) Query: 1014 ETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER-DGEIIKPKKNKYDFEKRGHIR 1072 E P + K V E A + V N A VVW G +++ + Y+ + + Sbjct: 1387 EEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQ 1446 Query: 1073 K-LYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFE 1127 L I S D G +C R+ ++C+ + + E P + +++ +V G A F Sbjct: 1447 YCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEAP-RFESIMEDVEVGAGETARFA 1505 Query: 1128 IELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 + + +G L + W+KD + S+H+ + + L + D G Y+C N Sbjct: 1506 V-VVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQN 1561 Score = 47.2 bits (107), Expect = 0.005 Identities = 61/278 (21%), Positives = 103/278 (37%), Gaps = 14/278 (5%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQ-FSNHIQLTIDGKKQKL 1163 PP L +Q V +G I + + +V W ++ ++ +G +L Sbjct: 868 PPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRL 927 Query: 1164 KIYDCDLDDAGEYSC----EVGNSKCTAILTVEE--PSINFTLRLP-EFILVPANTDAYL 1216 +I + DAG Y+C E G +C A L V S + + P + + V A A Sbjct: 928 RILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALF 987 Query: 1217 TVEIPDET-LDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 + T ++V W + +++ K + D +K L++ EDD YTC L AK Sbjct: 988 ECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAK 1047 Query: 1275 STTKLKVEVVEFP---PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 + P P + + G P P W +++ Sbjct: 1048 DELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEES 1107 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 ++ + D SL I V + D G+Y + N G A Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQA 1145 Score = 46.0 bits (104), Expect = 0.011 Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 7/116 (6%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P + PLK+ V G V L V G P P + W ++ + LP + S L+ Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDG---QLLP--APAPEPSCLWLRR 97 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITV-EEPTEENAEPPLF-INRFQEITVKEKG 848 +D GVY+ A+N G A AV+TV E E AE + + Q + +++ G Sbjct: 98 CGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDG 153 Score = 44.0 bits (99), Expect = 0.046 Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Query: 496 PVFEKPTSEEQSMAP-IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQ 554 P + +S+ S AP F L + +G V +V+G P+P ++W R ++P Q Sbjct: 854 PSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQ 913 Query: 555 DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 + + L I DAG +TC A N G L V A Sbjct: 914 RRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRA 961 Score = 43.2 bits (97), Expect = 0.081 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 6/150 (4%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 P P + W K+ L ++ I + K+ ++ I + H+ Y A+N G+ + Sbjct: 2611 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD 1718 T+ V P K P + + +++ + WKP D T Y +E+ + W V+ Sbjct: 2671 TVAVARVPGKLAPPEV-TQTYQDTALVLWKP--GDSRAPCT-YTLERRVDGESVWHPVSS 2726 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 D Y + L FRV N G Sbjct: 2727 GIPDC-YYNVTHLPVGVTVRFRVACANRAG 2755 Score = 42.7 bits (96), Expect = 0.11 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 8/92 (8%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP+F+ L+ GS V+ V G P P + WFR ++ P+ + L Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDGQLL-PA-------PAPEPSCL 93 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +R +DAG ++C+A+N G AS L V Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125 Score = 42.7 bits (96), Expect = 0.11 Identities = 18/76 (23%), Positives = 40/76 (52%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G + L+ +I PPP+V W+K+G+ L ++ + + + + ++E + + + Y Sbjct: 736 GADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMAT 795 Query: 1647 ASNTAGTSSVEVTLKV 1662 A+N G ++ +L V Sbjct: 796 ATNELGQATCAASLTV 811 Score = 41.1 bits (92), Expect = 0.33 Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 3/100 (3%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXX 1540 +P +PLKN D+ L + G P P + W+RDG+ L A Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPHPILRWFRDGQLL---PAPAPEPSCLWLRRC 98 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 Y C+A N+ G V+ + + + +DI Sbjct: 99 GAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDI 138 Score = 40.3 bits (90), Expect = 0.57 Identities = 46/226 (20%), Positives = 76/226 (33%), Gaps = 9/226 (3%) Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 Y V+ A + +V + +S V PL+++ E C+ G +V Sbjct: 940 YTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEV 999 Query: 1514 TWYRDGKKLKTA----KATYENRX-XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 W G+ L+ A K ++ R Y C E+ S + ++ Sbjct: 1000 DWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVR 1059 Query: 1569 QK--PVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEK 1626 P+ T ED++ G I G PPP V W G +E + + Sbjct: 1060 PSLAPLFTRLLEDVEVLE--GRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGG 1117 Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + I + Y + A NT G + L V + + GP Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP 1163 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%) Query: 1113 LQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 LQN V G + +T V W KDGS ++ + L +G++ L + + Sbjct: 728 LQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAA 787 Query: 1172 DAGEYSC----EVGNSKCTAILTV 1191 DAG Y E+G + C A LTV Sbjct: 788 DAGSYMATATNELGQATCAASLTV 811 Score = 39.1 bits (87), Expect = 1.3 Identities = 40/191 (20%), Positives = 71/191 (37%), Gaps = 13/191 (6%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS 1344 +FPP ++ + G TLL A P P+ W+ + KK ++PS+ S Sbjct: 2581 DFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD----KKSLRSEPSVIIVSCK 2636 Query: 1345 -----LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 L+I + AG+Y+ N G V + P P + + + + Sbjct: 2637 DGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQTYQDTALV 2696 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W ++ T Y +E + + W V + I ++ +L + RFR N Sbjct: 2697 LWKPGDSRAPCT---YTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANR 2753 Query: 1459 VDISDASETTE 1469 S ++E Sbjct: 2754 AGQGPFSNSSE 2764 Score = 38.3 bits (85), Expect = 2.3 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 5/109 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K K Q + EG L C A P P I+W+ + + + ++ + D Sbjct: 2583 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR--- 2639 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIE 739 +L I K G Y A N G +S + + G+ PP+V + Sbjct: 2640 QLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVTQ 2688 Score = 37.5 bits (83), Expect = 4.0 Identities = 24/100 (24%), Positives = 35/100 (35%), Gaps = 1/100 (1%) Query: 505 EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDN 564 E P+F KL+ + +G C P P I+W + ++ + D Sbjct: 2579 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDG 2638 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAG-FASSTTELIVEAP 603 L I AG + C A N G SS T + P Sbjct: 2639 RQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678 Score = 37.1 bits (82), Expect = 5.3 Identities = 22/95 (23%), Positives = 36/95 (37%), Gaps = 5/95 (5%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY-----ENRXXXX 1536 P LK+ E L C+ P P ++W +D K L++ + + R Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 Y+C A N G + +SC V + + P Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678 Score = 36.3 bits (80), Expect = 9.2 Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 4/111 (3%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSIT 790 PP LK ++ +GE+ L P P I+W K+ K +++ P+ S D + Sbjct: 2583 PPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLL 2642 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQE 841 + + G+Y A N G +S + V + A PP +Q+ Sbjct: 2643 SIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLA-PPEVTQTYQD 2692 >UniRef50_P97798 Cluster: Neogenin precursor; n=37; Euteleostomi|Rep: Neogenin precursor - Mus musculus (Mouse) Length = 1493 Score = 103 bits (247), Expect = 5e-20 Identities = 137/592 (23%), Positives = 226/592 (38%), Gaps = 57/592 (9%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKT---AKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 L C+ G+P P V W ++ + L T + Y CIA N + Sbjct: 279 LPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEISDVTEDDAGTYFCIADNGNK 338 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 VE + +Q P +I + + + + G P P V W KNG+ + Sbjct: 339 TVEAQAELTVQVPPGFLKQPANIYAHESM--DIVFECEVTGKPTPTVKWVKNGDVVIPSD 396 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK----PSKPE--- 1670 + I + V+ L +S Y A N G + L + + P+ P Sbjct: 397 NFKIVKEHNLQVLG---LVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSL 453 Query: 1671 -------------GP-------VIMREISRESVTIEWKPPLDDG-GLELTKYAIEKHEPD 1709 GP V+ +S + + W+ P D G LT E Sbjct: 454 TSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGV 513 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP-S 1768 + ++ +++ IQ L Y+F+V+AQN G E+ S P+ ++T +V Sbjct: 514 DRERVENTSQPGEMQV-TIQNLMPATVYIFKVMAQNKHGSGES--SAPLRVETQPEVQLP 570 Query: 1769 XXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQK 1828 S+ +TW + +G I +YK+ ++G + I Sbjct: 571 GPAPNIRAYATSPTSITVTW-ETPLSGNGEIQNYKLYYMEKGTDKEQDIDVSSHSYTING 629 Query: 1829 LSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTSRSVTLKW 1886 L T Y FR+ A N+ G P S + + +TL+ P + P+N + S+S+ + W Sbjct: 630 LKKYTEYSFRVVAYNKHG---PGVSTQDVAV-RTLSDVPSAAPQNLSLEVRNSKSIVIHW 685 Query: 1887 TEPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENT 1945 P S IT Y I ++ KS V G+ IE + E FR++A Sbjct: 686 QPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTV 745 Query: 1946 VGVSLPTESQSVRLEK----HATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 G T+ S + VP P++ L +R + ++IV+ SW PE + + GY Sbjct: 746 NGTGPATDWLSAETFESDLDETRVPEVPSS-LHVRPLVTSIVV-SWTPPE-NQNIVVRGY 802 Query: 2002 NIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 AI + + KVD + I +L + Y+I + A N +G PL Sbjct: 803 --AIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPL 852 Score = 84.6 bits (200), Expect = 3e-14 Identities = 79/326 (24%), Positives = 130/326 (39%), Gaps = 21/326 (6%) Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPS-KPEGP---VIMREISRESVTIEWKPPLDDGGLEL 1698 + + A N G+ L+V +P + GP + S S+T+ W+ PL G E+ Sbjct: 542 FKVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNG-EI 600 Query: 1699 TKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 Y + E + K D+D +Y I L + EY FRV+A N G + ++ + Sbjct: 601 QNYKLYYMEKGTD---KEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHG--PGVSTQDV 655 Query: 1759 VIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEGKK---WK 1814 ++T DVPS +++S+ I W PS I YK+ ++ +K + Sbjct: 656 AVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTE 715 Query: 1815 XXXXXXXXXARIQKLSINTTYQFRIYAR--NEIGTSLPYTSDDKITIGKTLT-PPSQPRN 1871 I+ L T Y FR+ A N G + + S + T P P + Sbjct: 716 TLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSS 775 Query: 1872 FVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIK 1931 V + S+ + WT PE N + Y I + G + + V + IEN+ Sbjct: 776 LHVRPLVT-SIVVSWTPPE-NQNIVVRGYAIGYGI--GSPHAQTIKVDYKQRYYTIENLD 831 Query: 1932 EKDEIIFRISAENTVGVSLPTESQSV 1957 + + A N VG +P +V Sbjct: 832 PSSHYVITLKAFNNVGEGIPLYESAV 857 Score = 83.4 bits (197), Expect = 6e-14 Identities = 78/299 (26%), Positives = 131/299 (43%), Gaps = 32/299 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+ +P+ V G+ +L C + A P + W + ++ D+ I V + S Sbjct: 163 PRFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQNRQPLLLDDRI-VKLPS------G 215 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-----KSMIVRQ 748 L I+N + G Y + V G ++K + +P ++++ + SM+ Sbjct: 216 TLVISNATEGDGGLYRCI-VESGGPPKFSDEAELKVLQ-DPEEIVDLVFLMRPSSMMKVT 273 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVK--DEGVYT 804 G+S +L V G P P + W KN + L T+S G + L+ V D G Y Sbjct: 274 GQSAVLPCVVSGLPAPVVRWMKNEE---VLDTESSGRLVLLAGGCLEISDVTEDDAGTYF 330 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A+N E A +TV+ P P F+ + I E I VT P P++ Sbjct: 331 CIADNGNKTVEAQAELTVQVP-------PGFLKQPANIYAHESMDIVFECEVTGKPTPTV 383 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W +N +++ PS+ + N++ V+ V S D G Y+C+A N G + GA++ I Sbjct: 384 KWVKNGDVVIPSDNF-KIVKEHNLQ-VLGLVKS--DEGFYQCIAENDVGNAQAGAQLII 438 Score = 71.7 bits (168), Expect = 2e-10 Identities = 203/1021 (19%), Positives = 357/1021 (34%), Gaps = 112/1021 (10%) Query: 1035 ILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNT--SVH---DEGEYS 1088 IL SE + ++ W++DG + + + D + L+I N S H DEG Y Sbjct: 82 ILNCSAYSEPSPNIEWKKDGTFLNLESD--DRRQLLPDGSLFISNVVHSKHNKPDEGFYQ 139 Query: 1089 CILRDE------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFK 1141 C+ + S TA++TV LP ++ + V GN A E+ VRW + Sbjct: 140 CVATVDNLGTIVSRTAKLTVAGLP-RFTSQPEPSSVYVGNSAILNCEVNADLVPFVRWEQ 198 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN------SKCTAILTVEEPS 1195 + + + I G L I + D G Y C V + S + +++P Sbjct: 199 NRQPLLLDDRIVKLPSGT---LVISNATEGDGGLYRCIVESGGPPKFSDEAELKVLQDPE 255 Query: 1196 ----INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 + F +R P ++ A L + V + K + DTE + + Sbjct: 256 EIVDLVFLMR-PSSMMKVTGQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGG 314 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVD 1310 L I TEDD Y C+ + T + + E+ V+ PP + D+ + Sbjct: 315 CLEISDVTEDDAGTYFCIADNGNKTVEAQAELTVQVPPGFLKQPANIYAHESMDIVFECE 374 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKK-------------VENTDAGI 1357 P P +W+ N ++ + K + L + K V N AG Sbjct: 375 VTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGA 434 Query: 1358 YKLRLENNCG----------HADVEMNVTILDKPSPPGKPNILE--IDSSSINICWDEPE 1405 + LE++ A + P P +++ + + I + W P Sbjct: 435 QLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPA 494 Query: 1406 NTGNSTIIYYVVEYQE--IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISD 1463 + + + Y V Y + +D + + Q +IQNL + Y F+ A N+ Sbjct: 495 SDPHGDNLTYSVFYTKEGVDRERVENTSQPGEMQVTIQNLMPATVYIFKVMAQNK---HG 551 Query: 1464 ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL--TCIFGGVPQPKVTWYRDGKK 1521 + E++ +V + ++Q P ++ T P T + G Y K Sbjct: 552 SGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITVTWETPLSGNGEIQNYKLYYMEKG 611 Query: 1522 LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVV--GIQQKPVITISNE 1578 + + ++ +A+N HG V T V + P N Sbjct: 612 TDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNL 671 Query: 1579 --DIKQKHKVGDEWLV--TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 +++ + W + G I Y+ ++ + E +T + + +I + Sbjct: 672 SLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLI--EG 729 Query: 1635 LKRSHSSKYTIEASNTAGTS------SVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEW 1687 L R + + A GT S E D+ PE P + S+ + W Sbjct: 730 LDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSW 789 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 PP ++ + + YAI + + VD Y I+ L+ + Y+ + A N V Sbjct: 790 TPP-ENQNIVVRGYAIGYGIGSPHA--QTIKVDYKQRYYTIENLDPSSHYVITLKAFNNV 846 Query: 1748 G----FSEALESEPIVIKTALDV--------------PSXXXXXXXXXXIDNESVYITWF 1789 G E+ + P + +D+ P + ++++ ITW Sbjct: 847 GEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWA 906 Query: 1790 PSEKNGGSPIID---YKVEIKQE---GKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 + I D Y V K K+K + L NT Y+F + Sbjct: 907 DNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYL-VTGLKPNTLYEFSVMVTK 965 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 +S + T T P + V E R++ + W +P S IT YII Sbjct: 966 GRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNW-QPPSEANGKITGYIIY 1024 Query: 1904 FKT---VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 + T + W I V G+ H I+ + F+I A N+ G+ +E+ R Sbjct: 1025 YSTDVNAEIHDWV-IEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTP 1083 Query: 1961 K 1961 K Sbjct: 1084 K 1084 Score = 69.3 bits (162), Expect = 1e-09 Identities = 95/384 (24%), Positives = 161/384 (41%), Gaps = 40/384 (10%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-----NNKPVKALPTKSDGDTHSITI 791 ++EP+ ++ VR G SVIL+ P P I W K N + DG + Sbjct: 67 LVEPVDTLSVR-GSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNV 125 Query: 792 LKPKKVK-DEGVYTLKA--ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 + K K DEG Y A +N I +A +TV A P F ++ + +V Sbjct: 126 VHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTV-------AGLPRFTSQPEPSSVYVGN 178 Query: 849 TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-V 907 + L V + VP + W +N + + + I + G LVI+N +E D G Y+C V Sbjct: 179 SAILNCEVNADLVPFVRWEQNRQPLLLDDRIVKLPSG---TLVISNA-TEGDGGLYRCIV 234 Query: 908 ASNSAGKSSHGARVTI--DVEKVTFVKHLQK--SYETEEGKTVILECQTSHTVS--TKWY 961 S K S A + + D E++ + L + S G++ +L C S + +W Sbjct: 235 ESGGPPKFSDEAELKVLQDPEEIVDLVFLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWM 294 Query: 962 HNKKEI-SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV----KDQETSTMLVVKETI 1016 N++ + + R ++ G D G CI K E L V + Sbjct: 295 KNEEVLDTESSGRLVLLAG--GCLEISDVTEDDAGTYFCIADNGNKTVEAQAELTV-QVP 351 Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F+++ + E + E E+ + T V W ++G+++ P N + K +++ L Sbjct: 352 PGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDN-FKIVKEHNLQVLG 410 Query: 1076 IRNTSVHDEGEYSCILRDESCTAE 1099 + + DEG Y CI ++ A+ Sbjct: 411 LVKS---DEGFYQCIAENDVGNAQ 431 Score = 65.3 bits (152), Expect = 2e-08 Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F +P + G +L C + +P P + W+ K EE++ E+ + + L Sbjct: 262 FLMRPSSMMKVTGQSAVLPCVVSGLPAPVVRWM-KNEEVLDTESSGRLVL----LAGGCL 316 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 +I++V + GTY +A N L ++ PP ++ ++ + ++ Sbjct: 317 EISDVTEDDAGTYFCIADNGNKTVEAQAELTVQV----PPGFLKQPANIYAHESMDIVFE 372 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 +V G P PT+ W KN V H++ +L K DEG Y AEN G A+ Sbjct: 373 CEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHNLQVLGLVK-SDEGFYQCIAENDVGNAQ 431 Query: 816 TSAVITVEE 824 A + + E Sbjct: 432 AGAQLIILE 440 Score = 63.3 bits (147), Expect = 7e-08 Identities = 80/336 (23%), Positives = 139/336 (41%), Gaps = 15/336 (4%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS ++L C + P P+I W G + + + + D ++ S + + K EG Sbjct: 78 GSSVILNCSAYSEPSPNIEWKKDGTFLNLESDDRRQLLPDGSLFISNVVHSKHNKPDEGF 137 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y VA + K+ T P +P S V G S IL+ +V + P + Sbjct: 138 YQCVATVDNLGTIVSRTAKL-TVAGLPRFTSQPEPSS-VYVGNSAILNCEVNADLVPFVR 195 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS--AVITVEEP 825 W +N +P+ L + ++ D G+Y E S G + S A + V + Sbjct: 196 WEQNRQPL-LLDDRIVKLPSGTLVISNATEGDGGLYRCIVE-SGGPPKFSDEAELKVLQD 253 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFD 884 EE + + + V + + L V+ P P + W +N E++ + S Sbjct: 254 PEEIVDLVFLMRPSSMMKVTGQSAV-LPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLA 312 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 G +E I++V +E D+G Y C+A N A +T+ V F+K Y E Sbjct: 313 GGCLE--ISDV-TEDDAGTYFCIADNGNKTVEAQAELTVQVPP-GFLKQPANIY-AHESM 367 Query: 945 TVILECQTS--HTVSTKWYHNKKEISGMDHREIIQE 978 ++ EC+ + T + KW N + D+ +I++E Sbjct: 368 DIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKE 403 Score = 60.9 bits (141), Expect = 4e-07 Identities = 62/297 (20%), Positives = 108/297 (36%), Gaps = 39/297 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + C V G P P + W + ++ ++ L I +V +DAGT+ C Sbjct: 274 GQSAVLPCVVSGLPAPVVRWMKNEEVLDTESSGRLVLLAGGC--LEISDVTEDDAGTYFC 331 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 ++D+G++ TV A++ +PP F K+P Sbjct: 332 --------------------IADNGNK-TVEAQ---------AELTVQVPPGFLKQPANI 361 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 Y E DI+ EC + P P + W+ G+ ++P +N + E + L++ + K Sbjct: 362 YAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHN-------LQVLGLVKS 414 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 EG Y +A N G A L I + P + + + + + PR Sbjct: 415 DEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPR 474 Query: 764 PTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + + + +K D H + EGV + EN+ E I Sbjct: 475 DVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVDRERVENTSQPGEMQVTI 531 Score = 48.8 bits (111), Expect = 0.002 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 4/91 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ + + + FEC+V G P P + W + ++ PS +F++ + + L Sbjct: 352 PGFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDNFKIVKEHN----LQ 407 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + + D G + C+A+N G A + +LI+ Sbjct: 408 VLGLVKSDEGFYQCIAENDVGNAQAGAQLII 438 >UniRef50_UPI0000E46659 Cluster: PREDICTED: similar to roundabout homolog 2; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to roundabout homolog 2 - Strongylocentrotus purpuratus Length = 1809 Score = 103 bits (246), Expect = 7e-20 Identities = 128/534 (23%), Positives = 212/534 (39%), Gaps = 54/534 (10%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-DTHSI 789 E+ P + E KS+IV +G+ + + G P PTI+W KN +P+ T+ D+ S+ Sbjct: 18 EESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSL 77 Query: 790 TILK----PKKVKDEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEITV 844 L+ + +D GVY A NS G A +A + + E+ E P+ + + Sbjct: 78 FFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPV-----SDQLI 132 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 + P P +TW ++++ I + + N+ L D D G Y Sbjct: 133 SGDSAVLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELRKD---DEGTY 189 Query: 905 KCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVSTKWY 961 KC A N AG + S A +T+ V K F+ Q + T G+ +L C+ + W Sbjct: 190 KCKAQNVAGERISKDAYLTVQV-KPAFINPPQDTI-TAPGEAAVLRCEVEGDPPPTVSWS 247 Query: 962 HNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD----QETSTMLVVKETIP 1017 E+ D R Q+ D GV C ++ + L V +P Sbjct: 248 REIGELP--DGR--TQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRV-SAVP 302 Query: 1018 EFIRKLQDFEVKEKDVAILEVE-INSETADVVWERDGE-----IIKPKKNKYDFEKRGHI 1071 +FIR +D V ++ + E + S + W++ G I ++ +++ G Sbjct: 303 DFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASG-- 360 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVTVV--------ELPPEIITRLQNQKVNKGNK 1123 +L I + D G Y C + AE V PP I NQ + G+ Sbjct: 361 -ELQINPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGST 419 Query: 1124 ATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 ATF + + W KDG + SN + ++ L+I +DD+G YSC + Sbjct: 420 ATFMCRSAGNPSPQIEWTKDGIALTTSNP-RFSLMYPDNTLEITGVQVDDSGLYSCLASS 478 Query: 1183 -----SKCTAILTVE--EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 S+ +L +E E S P +P + L V + ++ V W Sbjct: 479 NSGETSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRW 532 Score = 89.0 bits (211), Expect = 1e-15 Identities = 78/293 (26%), Positives = 127/293 (43%), Gaps = 19/293 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT +++PK+ V G C+ PEP I+WL G+ +V + ++S + Sbjct: 22 PTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSLFFLQ 81 Query: 694 VLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 V + N + Q+ G Y +A N G A S L+I ++ + EP+ ++ + Sbjct: 82 V--VGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFRE--EPVSDQLISGDSA 137 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 V+ G P P +TW K+++P+ + +LK + DEG Y KA+N Sbjct: 138 VLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGNLLLKELRKDDEGTYKCKAQNVA 197 Query: 812 G-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A +TV+ P FIN Q+ L V +P P+++W R Sbjct: 198 GERISKDAYLTVQ-------VKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSR-- 248 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 EI + TQ ++ + T+ E+D G Y C A N G S AR+ + Sbjct: 249 EIGELPDGRTQQLPDNSLRIRHTD---ELDDGVYICTAENIWGTSDAKARLRV 298 Score = 83.4 bits (197), Expect = 6e-14 Identities = 102/425 (24%), Positives = 169/425 (39%), Gaps = 53/425 (12%) Query: 495 LPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKP 552 L F P + AP E+ + G F C+ EG P P I+W + Q +I+ Sbjct: 7 LATFVSPGRRTEESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRD 66 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMT 612 ++ + +V +D G + C+A N+ G A S + A L + E Sbjct: 67 TRHTVLDSGSLFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEP 126 Query: 613 VXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGE 672 V +LE PP P+ ++ + I+L+ V Sbjct: 127 VSDQLISGDSA----VLECTPPRGYPTPEVTWLKDDQPIILDNNRV-------------- 168 Query: 673 EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGE 731 +IV D N+ +LK ++K EGTY A N GE S L ++ Sbjct: 169 KIVEDGNL-------------LLK--ELRKDDEGTYKCKAQNVAGERISKDAYLTVQV-- 211 Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 P I P + I GE+ +L +V G+P PT++W + + T+ D +S+ I Sbjct: 212 --KPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREIGELPDGRTQQLPD-NSLRI 268 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 ++ D+GVY AEN G ++ A + V + P FI ++ TV ++ Sbjct: 269 RHTDEL-DDGVYICTAENIWGTSDAKARLRV-------SAVPDFIRAPRDKTVHVNEMVR 320 Query: 852 LVARVTRNPVPSITWYR---NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVA 908 +P PSI W + + ++ ++ + + EL I V + D+G Y C A Sbjct: 321 FQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMD-DAGTYICYA 379 Query: 909 SNSAG 913 + G Sbjct: 380 TGGTG 384 Score = 82.6 bits (195), Expect = 1e-13 Identities = 71/298 (23%), Positives = 118/298 (39%), Gaps = 23/298 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P F P+ G +L C + P P ++W + E+ PD ++ Sbjct: 211 VKPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREIGEL-PDGRTQQLPDNS---- 265 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L+I + + +G Y A N G + L++ P I + V E Sbjct: 266 ---LRIRHTDELDDGVYICTAENIWGTSDAKARLRVSA----VPDFIRAPRDKTVHVNEM 318 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-----LKPKKVKDEGVYTLK 806 V + VG+P P+I W K L ++ + P ++ D G Y Sbjct: 319 VRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTYICY 378 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A G+AE AV+ V + E A PPL T+ T + R NP P I W Sbjct: 379 ATGGTGVAEAKAVLRVLD--ESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQIEW 436 Query: 867 YRNNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++ ++ S + + +E+ VD DSG Y C+AS+++G++S A + + Sbjct: 437 TKDGIALTTSNPRFSLMYPDNTLEITGVQVD---DSGLYSCLASSNSGETSQSATLLV 491 Score = 62.1 bits (144), Expect = 2e-07 Identities = 73/298 (24%), Positives = 114/298 (38%), Gaps = 24/298 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F + P+ + V + +C V P P I W G E +N+ + S Sbjct: 302 PDFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTE----DNLLFINQQRGRFEVS 357 Query: 694 V---LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIVRQ 748 L+I V+ GTY A G A VL++ PP +I+ P +V Sbjct: 358 ASGELQINPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLV-V 416 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 G + + GNP P I W K+ + + P S + + +V D G+Y+ A Sbjct: 417 GSTATFMCRSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLA 476 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL-VARVT--------- 857 ++ G SA + V E TE + P E+ +++ V R + Sbjct: 477 SSNSGETSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPA 536 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV--ASNSAG 913 N PS+T Y+ E SP G I+ N++ + S + V A NS G Sbjct: 537 ANRAPSVTGYQ-VEYFSPERVTGWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNG 593 Score = 60.1 bits (139), Expect = 7e-07 Identities = 110/512 (21%), Positives = 189/512 (36%), Gaps = 55/512 (10%) Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEV 1100 T +V W +D + I N+ + G+ L ++ DEG Y C ++ E + + Sbjct: 149 TPEVTWLKDDQPIILDNNRVKIVEDGN---LLLKELRKDDEGTYKCKAQNVAGERISKDA 205 Query: 1101 TV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQFSNHIQLTID 1157 + V++ P I Q+ G A E+ +GD V W ++ E+ QL Sbjct: 206 YLTVQVKPAFINPPQDTITAPGEAAVLRCEV-EGDPPPTVSWSREIGELPDGRTQQLP-- 262 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEEPSINFTLRLPEFILVPANTD 1213 L+I D D G Y C G S A L V ++ +R P V N Sbjct: 263 --DNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVS--AVPDFIRAPRDKTVHVNEM 318 Query: 1214 AYLTVE-IPDETLDVTWYK---KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 E + + W K + +++ ++ L I DD Y C Sbjct: 319 VRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINPVQMDDAGTYICY 378 Query: 1270 ------LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 + +AK+ ++ E + PP I + GS T + P P EW Sbjct: 379 ATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMCRSAGNPSPQIEWTK 438 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK--- 1380 + I + + S+ +L I V+ D+G+Y +N G + +++ Sbjct: 439 DG-IALTTSNPRFSLMYPDNTLEITGVQVDDSGLYSCLASSNSGETSQSATLLVIESTET 497 Query: 1381 --------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID-TT 1425 P P +P + + SSI + W P ++ Y VEY + T Sbjct: 498 SGIPVKTAPSINELPGSPSQPLRVNVTRSSIQVRWTAPAANRAPSVTGYQVEYFSPERVT 557 Query: 1426 EWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 W+ N + +T +I +L +SS+ A+N I +E +ET P+ Sbjct: 558 GWVVAGNGIQGETYNINHLVPSSSHLVVVRAINSNGIGPPGPMSESISTSEETANPPPSR 617 Query: 1485 EKPLKNITTEPNEDIELTCIFG-GVPQPKVTW 1515 E ++ + + +E+T I KV+W Sbjct: 618 E----CLSDQSSITVEITTIIALSSTAIKVSW 645 Score = 53.2 bits (122), Expect = 8e-05 Identities = 79/414 (19%), Positives = 154/414 (37%), Gaps = 29/414 (7%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK--IIKKCKHTKPSIDSKS 1342 E P I + + + RG + + P+P W+ N + +I+ +HT +DS S Sbjct: 19 ESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTV--LDSGS 76 Query: 1343 A---SLTIKKVENTDAGIYKLRLENNCG---HADVEMNVTIL--DKPSPPGKPNILEIDS 1394 + + D G+Y+ N+ G A+ + + L D P ++ DS Sbjct: 77 LFFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDS 136 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + + C P + + ++ + Q I + VK + ++ L+ + ++ Sbjct: 137 AVLE-C--TPPRGYPTPEVTWLKDDQPI-ILDNNRVKIVEDGNLLLKELRKDDEGTYKCK 192 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVT 1514 A N ++ + + Y ++ P P ++ T P E L C G P P V+ Sbjct: 193 AQN---VAGERISKDAYLTVQV----KPAFINPPQDTITAPGEAAVLRCEVEGDPPPTVS 245 Query: 1515 WYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 W R+ +L + Y C A N G + + + P Sbjct: 246 WSREIGELPDGRTQQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFI 305 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG---NKLENDKEYNITTKEKTSVIR 1631 + D K H V + G PPP + W K G N L +++ + ++ Sbjct: 306 RAPRD-KTVH-VNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQ 363 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 I ++ + Y A+ G + + L+V D+ P P+I + +++ + Sbjct: 364 INPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPP-PLIQYGPANQTLVV 416 Score = 49.2 bits (112), Expect = 0.001 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 5/81 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 GST F C+ G P PQI W + A+ + F + Y D+ TL I V +D+G ++ Sbjct: 417 GSTATFMCRSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDN---TLEITGVQVDDSGLYS 473 Query: 583 CVAKNAAGFAS-STTELIVEA 602 C+A + +G S S T L++E+ Sbjct: 474 CLASSNSGETSQSATLLVIES 494 Score = 48.4 bits (110), Expect = 0.002 Identities = 97/473 (20%), Positives = 169/473 (35%), Gaps = 60/473 (12%) Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-D 1370 + +P P W+ + + I + ++ +L +K++ D G YK + +N G Sbjct: 145 RGYPTPEVTWLKDDQPIILDNNRVKIVED--GNLLLKELRKDDEGTYKCKAQNVAGERIS 202 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-S 1429 + +T+ KP+ IN D G + ++ VE T W Sbjct: 203 KDAYLTVQVKPA-------------FINPPQDTITAPGEAAVLRCEVEGDPPPTVSWSRE 249 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS-----PTV 1484 + + +T Q L NS R +E+D T E + K + P Sbjct: 250 IGELPDGRT--QQLPDNS---LRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDF 304 Query: 1485 EKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK-----LKTAKATYENRXXXXXXX 1539 + ++ T NE + C G P P + W + G + + + +E Sbjct: 305 IRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQI 364 Query: 1540 X--XXXXXXXYKCIAFNDHGEVETSCVVGIQQK---PVITISNEDIKQKHKVGDEWLVTA 1594 Y C A G E V+ + + P I Q VG Sbjct: 365 NPVQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAPPPLIQYGPANQTLVVGSTATFMC 424 Query: 1595 VIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGT 1653 G P P++ W K+G L ++ +++ + T + I ++ S Y+ AS+ +G Sbjct: 425 RSAGNPSPQIEWTKDGIALTTSNPRFSLMYPDNT--LEITGVQVDDSGLYSCLASSNSGE 482 Query: 1654 SSVEVTLKVYDK-----------------PSKPEGPVIMREISRESVTIEWKPPLDDGGL 1696 +S TL V + P P P+ + ++R S+ + W P + Sbjct: 483 TSQSATLLVIESTETSGIPVKTAPSINELPGSPSQPLRVN-VTRSSIQVRWTAPAANRAP 541 Query: 1697 ELTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 +T Y +E P+ W+ VA ETY I L + ++ V A N G Sbjct: 542 SVTGYQVEYFSPERVTGWV-VAGNGIQGETYNINHLVPSSSHLVVVRAINSNG 593 Score = 44.4 bits (100), Expect = 0.035 Identities = 80/395 (20%), Positives = 142/395 (35%), Gaps = 34/395 (8%) Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHI 1071 +E+ P + + V D A + + W ++G+ + + ++ G + Sbjct: 18 EESAPTITEQPKSLIVTRGDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSL 77 Query: 1072 RKLYI--RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124 L + D G Y C+ + S A + + L + + ++ G+ A Sbjct: 78 FFLQVVGNRQGGQDGGVYQCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDSA 137 Query: 1125 TFEIELTKGDAL--VRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVG 1181 E +G V W KD I N+ +++ DG L + + DD G Y C+ Sbjct: 138 VLECTPPRGYPTPEVTWLKDDQPIILDNNRVKIVEDGN---LLLKELRKDDEGTYKCKAQ 194 Query: 1182 N------SKCTAILTVE-EPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKK 1233 N SK A LTV+ +P+ + P+ + A L E+ D V+W ++ Sbjct: 195 NVAGERISK-DAYLTVQVKPAF---INPPQDTITAPGEAAVLRCEVEGDPPPTVSWSREI 250 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVD 1292 + D + +L IR E D Y C + T+ K + V P + Sbjct: 251 GELPDGRT----QQLPDNSLRIRHTDELDDGVYICTAENIWGTSDAKARLRVSAVPDFIR 306 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWI---VNSKIIKKCKHTKPSIDSKSASLTIKK 1349 R+ + V + P P+ W ++ + S S L I Sbjct: 307 APRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQRGRFEVSASGELQINP 366 Query: 1350 VENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 V+ DAG Y G A+ + + +LD+ P Sbjct: 367 VQMDDAGTYICYATGGTGVAEAKAVLRVLDESLAP 401 Score = 41.1 bits (92), Expect = 0.33 Identities = 45/170 (26%), Positives = 77/170 (45%), Gaps = 15/170 (8%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKR--SHSSKY 1643 GD EG P P + W KNG L D + + +++ ++ Y Sbjct: 36 GDPASFNCKAEGRPEPTISWLKNGQPLVIRDTRHTVLDSGSLFFLQVVGNRQGGQDGGVY 95 Query: 1644 TIEASNTAGTS-SVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKY 1701 A N+ GT+ S TL++ Y + E PV + IS +S +E PP E+T Sbjct: 96 QCMAHNSLGTAYSANATLEIAYLREDFREEPVSDQLISGDSAVLECTPPRGYPTPEVT-- 153 Query: 1702 AIEKHEP---DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 ++ +P DNNR +K+ + D ++ +++L ++ E ++ AQN G Sbjct: 154 WLKDDQPIILDNNR-VKIVE-DGNL---LLKELRKDDEGTYKCKAQNVAG 198 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 4/97 (4%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR---QTAIIKPSQDFQMYYDDD 563 S P F+ R K V+F+C+ G P P I W + + ++ +Q + ++ Sbjct: 299 SAVPDFIRAPRDKTVHVNEMVRFQCEAVGSPPPSIHWQKAGTEDNLLFINQQ-RGRFEVS 357 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L I V +DAGT+ C A G A + L V Sbjct: 358 ASGELQINPVQMDDAGTYICYATGGTGVAEAKAVLRV 394 >UniRef50_Q4SK53 Cluster: Chromosome 2 SCAF14570, whole genome shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 2 SCAF14570, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1792 Score = 103 bits (246), Expect = 7e-20 Identities = 86/383 (22%), Positives = 146/383 (38%), Gaps = 17/383 (4%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 G + L P P W N K I+ + K + SL I+ V + G+YK Sbjct: 223 GKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSVRHAHGGVYKSV 282 Query: 1362 LENNCGHADVEMNVTILD-KPSPP-GKPNILEIDSSSINICWDEPENTGNS---TIIYYV 1416 + N G A ++ + D P PP G P I I +I + W +P+ S + + Y Sbjct: 283 ISNKVGKATCYAHLYVTDILPDPPDGTPVIESITGKTITLSWKKPKRLDPSIDPSSLMYA 342 Query: 1417 VEYQEIDTTEW-ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK 1475 ++ Q + + +W I + T +I +L Y FR + S S T+ +++ Sbjct: 343 IQQQSLGSIQWTIIASGLKDTMYTISSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLLD 402 Query: 1476 ETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--- 1530 ++P + + + N+ + +T V V W R G L + YE Sbjct: 403 RGPYLQEAPIIVDKPEIVYVIENQSVTITITLNHV-NAAVLWKRKGVILASKPGVYEMSM 461 Query: 1531 ---NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 ++ +A N HG + V + P ED+ G Sbjct: 462 PDDDQHTLKLFKVKSDDIGEMTFMASNKHGNDGCTFSVEMAAAPTFETIMEDLDVC--AG 519 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + V+EG P P+++W+K+ + L Y + + + S YT A Sbjct: 520 ESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTA 579 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPE 1670 N AG+ S + L V++ SK E Sbjct: 580 RNLAGSVSCKAELTVHEAISKEE 602 Score = 97.1 bits (231), Expect = 5e-18 Identities = 113/546 (20%), Positives = 223/546 (40%), Gaps = 45/546 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F KL +G +F+C+V G P PQ+TW ++ S+D ++ + +L+ Sbjct: 83 PLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFDHLLTESEDIRILQEGGR-HSLI 141 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXXA 626 I V ED G + A+N G A ++ EL ++ P +S ++M Sbjct: 142 ISHVTKEDEGFYIVTARNCHGEAETSAELYIQEPRPAISSQMAKMEKMPSIPEEPEIPEN 201 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 ++ P F K V EG + +L+C++ +P P I W G+ I E+ + Sbjct: 202 EVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLR 261 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 D+H L I +V+ G Y V N+ G+A+ L + +PP ++S+ Sbjct: 262 DVHS----LVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILPDPPDGTPVIESI-- 315 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 G+++ LS + P+I + + A+ +S G I K + +YT+ Sbjct: 316 -TGKTITLSWKKPKRLDPSI---DPSSLMYAIQQQSLGSIQWTIIASGLK---DTMYTI- 367 Query: 807 AENSEGIAETSAVITV-----EEPTEEN------------AEPPLFINRFQEITVKEKGT 849 + S+G+ V+T+ +P+ E P+ +++ + + V E + Sbjct: 368 SSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLLDRGPYLQEAPIIVDKPEIVYVIENQS 427 Query: 850 IKLVARVTRNPV-PSITWYRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKC 906 + + +T N V ++ W R I++ + + D + L + V S+ D G+ Sbjct: 428 VTIT--ITLNHVNAAVLWKRKGVILASKPGVYEMSMPDDDQHTLKLFKVKSD-DIGEMTF 484 Query: 907 VASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT--VILECQTSHTVSTKWYHNK 964 +ASN G + G ++++ + + + + G++ + + W+ + Sbjct: 485 MASNKHG--NDGCTFSVEMAAAPTFETIMEDLDVCAGESPRFAVVVEGKPVPDILWFKSD 542 Query: 965 KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 ++ H + + D GV C ++ S + T+ E I K + Sbjct: 543 SLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTARNLAGSVSCKAELTVHEAISKEE 602 Query: 1025 DFEVKE 1030 E +E Sbjct: 603 PIEDEE 608 Score = 85.0 bits (201), Expect = 2e-14 Identities = 112/446 (25%), Positives = 183/446 (41%), Gaps = 49/446 (10%) Query: 491 KIDKLPVF----EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 K++K+P E P +E E+ P F++ L +G +C+V G P P I WF Sbjct: 185 KMEKMPSIPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFH 244 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 I+ ++D +M D V +LVIR V G + V N G A+ L V L Sbjct: 245 NGKRIESTEDRKMTQLRD-VHSLVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILP 303 Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFS-KKPKAQYVDEGSDILLECRLVAIPEPD 664 D V + + G T S KKPK +D D + AI + Sbjct: 304 DPPDGTPV------------IESITGKTITLSWKKPKR--LDPSID--PSSLMYAIQQQS 347 Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 + + I+ ++ M+ S+ K F+ T T A ++ A+ P+ Sbjct: 348 LG-------SIQWTIIASGLKDTMYTISSLSKGLRY-AFRVLTITSKAFSKPSPATDPVQ 399 Query: 725 LKIKTGE--KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-----NKPVKA 777 L + G +E P +++ + + V + +SV ++ + + + W + +KP Sbjct: 400 L-LDRGPYLQEAPIIVDKPEIVYVIENQSVTITI-TLNHVNAAVLWKRKGVILASKPGVY 457 Query: 778 LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 + D D H++ + K K D G T A N G +V E A P F Sbjct: 458 EMSMPDDDQHTLKLFKVKS-DDIGEMTFMASNKHG--NDGCTFSV-----EMAAAPTFET 509 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 +++ V + + V PVP I W++++ +++ S T +D LV+ N Sbjct: 510 IMEDLDVCAGESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACP 569 Query: 898 EIDSGDYKCVASNSAGKSSHGARVTI 923 E DSG Y C A N AG S A +T+ Sbjct: 570 E-DSGVYTCTARNLAGSVSCKAELTV 594 Score = 79.4 bits (187), Expect = 1e-12 Identities = 51/210 (24%), Positives = 100/210 (47%), Gaps = 10/210 (4%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G+P P ++W+ NG ++E+ ++ +T + I+ ++ +H Y Sbjct: 223 GKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSVRHAHGGVYKSV 282 Query: 1647 ASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702 SN G ++ L V D P P+G ++ I+ +++T+ WK P D ++ + YA Sbjct: 283 ISNKVGKATCYAHLYVTDILPDPPDGTPVIESITGKTITLSWKKPKRLDPSIDPSSLMYA 342 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVI- 1760 I++ + +W +A +D Y I L++ Y FRV+ FS+ + ++P+ + Sbjct: 343 IQQQSLGSIQWTIIASGLKDT-MYTISSLSKGLRYAFRVLTITSKAFSKPSPATDPVQLL 401 Query: 1761 ---KTALDVPSXXXXXXXXXXIDNESVYIT 1787 + P I+N+SV IT Sbjct: 402 DRGPYLQEAPIIVDKPEIVYVIENQSVTIT 431 Score = 72.1 bits (169), Expect = 2e-10 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 1/103 (0%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S E + AP F + G + +F VEG P P I WF+ +++ S + YDD Sbjct: 498 SVEMAAAPTFETIMEDLDVCAGESPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDD 557 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 N +LV+ PED+G +TC A+N AG S EL V +S Sbjct: 558 -NECSLVVLNACPEDSGVYTCTARNLAGSVSCKAELTVHEAIS 599 Score = 71.3 bits (167), Expect = 3e-10 Identities = 80/302 (26%), Positives = 122/302 (40%), Gaps = 44/302 (14%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM---YCSVLKITNVKKFQ 704 G +L EC + + D+ WL G+ I P + MH C +L + +V + Sbjct: 1 GETVLFECHIRGPKDTDVDWLADGKLIQP-----ALLNCKMHFDGRKCRLL-LNSVHEDD 54 Query: 705 EGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 GTYT ++ +E S K++ P L + V +G + +V G P Sbjct: 55 SGTYTCKLSTAKEEVISCG---KLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPS 111 Query: 764 PTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P +TW + + + + +G HS+ I K +DEG Y + A N G AETSA + Sbjct: 112 PQVTWSHFDHLLTESEDIRILQEGGRHSLIISHVTK-EDEGFYIVTARNCHGEAETSAEL 170 Query: 821 TVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKLVA 854 ++EP EE P P FI ++ V E L Sbjct: 171 YIQEPRPAISSQMAKMEKMPSIPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKC 230 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 +V P P+I W+ N + I +E + LVI +V G YK V SN GK Sbjct: 231 KVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSLVIRSV-RHAHGGVYKSVISNKVGK 289 Query: 915 SS 916 ++ Sbjct: 290 AT 291 Score = 67.7 bits (158), Expect = 3e-09 Identities = 97/374 (25%), Positives = 147/374 (39%), Gaps = 73/374 (19%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582 G TV FEC + G + W +I+P+ + +M++D L++ V +D+GT+T Sbjct: 1 GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRK-CRLLLNSVHEDDSGTYT 59 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C A S +L V P +D DILE Sbjct: 60 CKLSTAKEEVISCGKLRV-IPSND-------------PLFTRKLDILE------------ 93 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 V EG + +C++ P P + W + E+I + E H L I++V K Sbjct: 94 --VIEGRNARFDCKVSGTPSPQVTWSHFDHLLTESEDIRILQEGGRHS----LIISHVTK 147 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTG-----------EKEP-----PQV--------- 737 EG Y V A N GEA L I+ EK P P++ Sbjct: 148 EDEGFYIVTARNCHGEAETSAELYIQEPRPAISSQMAKMEKMPSIPEEPEIPENEVERFT 207 Query: 738 ----IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD---GDTHSIT 790 I+PL + V +G+ +L +V G P PTI W N K +++ + D HS+ Sbjct: 208 MPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIESTEDRKMTQLRDVHSL- 266 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTI 850 +++ + GVY N G A A + V T+ +PP + IT K TI Sbjct: 267 VIRSVRHAHGGVYKSVISNKVGKATCYAHLYV---TDILPDPPDGTPVIESITGK---TI 320 Query: 851 KLVARVTRNPVPSI 864 L + + PSI Sbjct: 321 TLSWKKPKRLDPSI 334 Score = 52.4 bits (120), Expect = 1e-04 Identities = 45/192 (23%), Positives = 85/192 (44%), Gaps = 15/192 (7%) Query: 1099 EVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHI-QLTI- 1156 E ++ PEI+ ++NQ V T I L +A V W + G + + ++++ Sbjct: 409 EAPIIVDKPEIVYVIENQSV------TITITLNHVNAAVLWKRKGVILASKPGVYEMSMP 462 Query: 1157 DGKKQKLKIYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANT 1212 D + LK++ DD GE S + GN CT +VE + + E + V A Sbjct: 463 DDDQHTLKLFKVKSDDIGEMTFMASNKHGNDGCT--FSVEMAAAPTFETIMEDLDVCAGE 520 Query: 1213 DAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 V + + + D+ W+K S++ ++ +T + D + +L++ +D YTC Sbjct: 521 SPRFAVVVEGKPVPDILWFKSDSLLAESSHYTFVYDDNECSLVVLNACPEDSGVYTCTAR 580 Query: 1272 DAKSTTKLKVEV 1283 + + K E+ Sbjct: 581 NLAGSVSCKAEL 592 Score = 51.2 bits (117), Expect = 3e-04 Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 9/191 (4%) Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDE-GVYTL 805 GE+V+ + G + W + K ++ L K D +L +D+ G YT Sbjct: 1 GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTC 60 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 K ++ VI+ + + PLF + + V E + +V+ P P +T Sbjct: 61 KLSTAK-----EEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVT 115 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + +++ SE I +G L+I++V E D G Y A N G++ A + I Sbjct: 116 WSHFDHLLTESEDIRILQEGGRHSLIISHVTKE-DEGFYIVTARNCHGEAETSAELYIQE 174 Query: 926 EKVTFVKHLQK 936 + + K Sbjct: 175 PRPAISSQMAK 185 Score = 50.0 bits (114), Expect = 7e-04 Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 1/95 (1%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F KLR +G V C G P P ITW + ++ M D L+ Sbjct: 1340 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLM 1399 Query: 570 IREVFPEDAGTFTCVAKN-AAGFASSTTELIVEAP 603 I + +DAG + CVA N A +SS T + P Sbjct: 1400 IMQTTKKDAGVYECVATNPLASVSSSCTISLARLP 1434 Score = 48.4 bits (110), Expect = 0.002 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 6/163 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN-ITTKEKTSVIRIKELKRSHSSKYTI 1645 GD ++ + G P P + W K+ LE D N I + ++ I + + + Y Sbjct: 1354 GDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLMIMQTTKKDAGVYEC 1413 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 A+N + S T+ + P++P P I ++ + ++ + W+P L Y++E+ Sbjct: 1414 VATNPLASVSSSCTISLARLPNRPGTPEIPQKYNNTALVL-WRP---SDTLAPCTYSLER 1469 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 W+ VA D Y + L FRV N G Sbjct: 1470 RAEGEPNWLIVATGVADC-YYNVVDLPAGGVIRFRVACVNKAG 1511 Score = 46.0 bits (104), Expect = 0.011 Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 8/116 (6%) Query: 712 AVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 A++RE A L K PP L+ ++ +G+ V LS G+P P ITW K+ Sbjct: 1318 AISRENSA-LRSRQYSKLASDFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKD 1376 Query: 772 NKPVKA-----LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 KP++ + DG H + I++ K KD GVY A N +S I++ Sbjct: 1377 KKPLEIDARMNMIACPDG-RHLLMIMQTTK-KDAGVYECVATNPLASVSSSCTISL 1430 Score = 44.8 bits (101), Expect = 0.026 Identities = 36/176 (20%), Positives = 72/176 (40%), Gaps = 7/176 (3%) Query: 1121 GNKATFEIELT-KGDALVRWFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 G FE + D V W DG IQ + + ++ DG+K +L + DD+G Y+C Sbjct: 1 GETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTC 60 Query: 1179 EVGNSK-----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKK 1233 ++ +K C + + FT +L ++ + + VTW Sbjct: 61 KLSTAKEEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFD 120 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPK 1289 ++ ++E ++ + + +LII T++D+ Y + + E+ P+ Sbjct: 121 HLLTESEDIRILQEGGRHSLIISHVTKEDEGFYIVTARNCHGEAETSAELYIQEPR 176 Score = 44.0 bits (99), Expect = 0.046 Identities = 36/176 (20%), Positives = 68/176 (38%), Gaps = 5/176 (2%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSA 1343 +FPP R++ + G VTL P P+ W+ + K ++ + + Sbjct: 1337 DFPPVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRH 1396 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L I + DAG+Y+ N +++ P+ PG P I + +++ + W Sbjct: 1397 LLMIMQTTKKDAGVYECVATNPLASVSSSCTISLARLPNRPGTPEIPQKYNNTALVLWRP 1456 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 + T Y +E + W+ V + ++ +L RFR VN+ Sbjct: 1457 SDTLAPCT---YSLERRAEGEPNWLIVATGVADCYYNVVDLPAGGVIRFRVACVNK 1509 Score = 40.3 bits (90), Expect = 0.57 Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 5/95 (5%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536 P L++ + + L+C+ G P P +TW +D K L+ A + R Sbjct: 1340 PVFHIKLRDHVLLEGDPVTLSCLPAGSPHPHITWMKDKKPLEIDARMNMIACPDGRHLLM 1399 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 Y+C+A N V +SC + + + P Sbjct: 1400 IMQTTKKDAGVYECVATNPLASVSSSCTISLARLP 1434 Score = 39.9 bits (89), Expect = 0.75 Identities = 41/175 (23%), Positives = 73/175 (41%), Gaps = 13/175 (7%) Query: 1032 DVAILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 + + E I + DV W DG++I+P G +L + + D G Y+C Sbjct: 2 ETVLFECHIRGPKDTDVDWLADGKLIQPALLNCKMHFDGRKCRLLLNSVHEDDSGTYTCK 61 Query: 1091 L---RDE--SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144 L ++E SC + P +L +V +G A F+ +++ V W Sbjct: 62 LSTAKEEVISCGKLRVIPSNDPLFTRKLDILEVIEGRNARFDCKVSGTPSPQVTWSHFDH 121 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY-----SCEVGNSKCTAILTVEEP 1194 + S I++ +G + L I +D G Y +C G ++ +A L ++EP Sbjct: 122 LLTESEDIRILQEGGRHSLIISHVTKEDEGFYIVTARNCH-GEAETSAELYIQEP 175 Score = 36.7 bits (81), Expect = 7.0 Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 6/114 (5%) Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKP 1058 I ++ E V + T+P+FI+ L D +V E A+L+ ++ +VW +G+ I+ Sbjct: 192 IPEEPEIPENEVERFTMPDFIKPLYDLDVIEGKEAVLKCKVAGLPYPTIVWFHNGKRIES 251 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108 +++ + R + L IR+ G Y ++ ++ +C A + V ++ P+ Sbjct: 252 TEDRKMTQLR-DVHSLVIRSVRHAHGGVYKSVISNKVGKATCYAHLYVTDILPD 304 >UniRef50_A7RZM7 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 629 Score = 103 bits (246), Expect = 7e-20 Identities = 92/349 (26%), Positives = 146/349 (41%), Gaps = 26/349 (7%) Query: 1627 TSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESV--- 1683 TSV+ + + Y A + V +K KPS P G V + + R S Sbjct: 221 TSVLTVHTYDDADFGPYVCVAMTPNTNQTHVVHIKRLHKPSAP-GNVTRQRLLRPSANCS 279 Query: 1684 ---TIEWKPPLDDGGLELTKYAIEKHEPDNNRW--IKVADVDRDVETYCIQKLNENCEYM 1738 ++ W PPLD+GG +T Y ++ +P W + A V+ C + Sbjct: 280 VQTSVTWMPPLDNGGSPVTHYDVQ-FKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLE 338 Query: 1739 FRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI--TWFPSEKNGG 1796 RV+A+N VG E E + I T P+ ++ YI TW +GG Sbjct: 339 MRVMARNVVGQGEPSE---VFIVTFWGEPTPPRNLAYRLVRNDGYPYIRVTWDYPYDDGG 395 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXX--ARIQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 + YKVE K G W R++K S Y+ R+ A N +G S P Sbjct: 396 VSVNGYKVEYKATGAAWARAIQTGTFAKEVRLEKKSNLKEYEIRVIAYNGVGPSKP---- 451 Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRS-----VTLKWTEPESNGGSPITNYIIEFKTVKG 1909 ++ PS+P N +S + + + ++W P NGGSPIT Y++E+K Sbjct: 452 SEVLKAAFAEKPSRPLNVGISATALNTNHGPHIQIRWDSPLDNGGSPITEYMVEYKEEVQ 511 Query: 1910 KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVR 1958 +W++ V +E + I + R+SA N++G P++ SV+ Sbjct: 512 TNWSQGRYVEVDRNEFILTGIDRNMKYDIRVSARNSMGYGPPSKVVSVK 560 Score = 101 bits (242), Expect = 2e-19 Identities = 72/275 (26%), Positives = 114/275 (41%), Gaps = 13/275 (4%) Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTT----YQFRIYA 1841 +TW P NGGSP+ Y V+ K G+ W I + R+ A Sbjct: 284 VTWMPPLDNGGSPVTHYDVQFKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLEMRVMA 343 Query: 1842 RNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 RN +G P + +T TPP +V + + W P +GG + Y Sbjct: 344 RNVVGQGEP-SEVFIVTFWGEPTPPRNLAYRLVRNDGYPYIRVTWDYPYDDGGVSVNGYK 402 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 +E+K G +W + + G E +E E R+ A N VG S P+E V Sbjct: 403 VEYKAT-GAAWARAIQTGTFAKEVRLEKKSNLKEYEIRVIAYNGVGPSKPSE---VLKAA 458 Query: 1962 HATVPSPP-TAPLEIRMVGSNI---VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 A PS P + + +N + W +P +GG+P+ Y + ++ +T W + Sbjct: 459 FAEKPSRPLNVGISATALNTNHGPHIQIRWDSPLDNGGSPITEYMVEYKEEVQTNWSQGR 518 Query: 2018 KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 V+V+ +F + + N Y IR+ ARN +G P Sbjct: 519 YVEVDRNEFILTGIDRNMKYDIRVSARNSMGYGPP 553 Score = 73.7 bits (173), Expect = 5e-11 Identities = 57/212 (26%), Positives = 86/212 (40%), Gaps = 9/212 (4%) Query: 1850 PYTSDDKITIGKTLTPPSQPRNFV------VSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 P T+ + K L PS P N S + S ++ W P NGGSP+T+Y ++ Sbjct: 244 PNTNQTHVVHIKRLHKPSAPGNVTRQRLLRPSANCSVQTSVTWMPPLDNGGSPVTHYDVQ 303 Query: 1904 FKTVKGKSWTKIVTVGGSVHEH-CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 FK W V + + H C + ++ + R+ A N VG P+E V Sbjct: 304 FKPFGEGWWEAETAVVNTPYIHMCRPRDQGRNGLEMRVMARNVVGQGEPSEVFIVTFWGE 363 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 T P L +R G + +W P DGG + GY + + T W + Sbjct: 364 PTPPRNLAYRL-VRNDGYPYIRVTWDYPYDDGGVSVNGYKVEYK-ATGAAWARAIQTGTF 421 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 + + S Y IR+ A N +G S+P E Sbjct: 422 AKEVRLEKKSNLKEYEIRVIAYNGVGPSKPSE 453 Score = 38.3 bits (85), Expect = 2.3 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK--NITKTQTSIQNLKTNSSYRFRAY 1454 I I WD P + G S I Y+VEY+E T W + + + + + + N Y R Sbjct: 484 IQIRWDSPLDNGGSPITEYMVEYKEEVQTNWSQGRYVEVDRNEFILTGIDRNMKYDIRVS 543 Query: 1455 AVNEVDISDASE 1466 A N + S+ Sbjct: 544 ARNSMGYGPPSK 555 >UniRef50_Q4S5Q4 Cluster: Chromosome 9 SCAF14729, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF14729, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 675 Score = 102 bits (244), Expect = 1e-19 Identities = 64/228 (28%), Positives = 100/228 (43%), Gaps = 3/228 (1%) Query: 1583 KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K K G + G P +V WY+ G +L ND + S + + +R + + Sbjct: 10 KVKAGQNAIFKMQFVGQDPIKVQWYREGEELLNDTNVRVEKCTSQSRLLLSRCQRKDTGE 69 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 I+ N G + L V DKPS P GP E S V W+PP DDGG ++ Y Sbjct: 70 IKIKLKNEHGVTEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSPVSHYV 129 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 +E+ + N W K+ V V TY ++ +Y +R+ A G SE +E++ + T Sbjct: 130 MERQQVGRNTWKKMG-VIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTSEMMETDEMQAGT 188 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG 1810 L P D + + + W GGS I+ Y +E +++G Sbjct: 189 -LAFPGPPAPPVVVSAFD-DCINLAWEAPSNRGGSRILGYILEKRKKG 234 Score = 74.9 bits (176), Expect = 2e-11 Identities = 51/194 (26%), Positives = 89/194 (45%), Gaps = 10/194 (5%) Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 M+V+ G SV ++ +P P I W K+N PV T S+ D+ S ++ + D G+Y Sbjct: 440 MVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTISNSDSSSQLLIPSSERSDSGIY 499 Query: 804 TLKAENSEGIAETSAVITVEE------PTEENAE---PPLFINRFQEITVKEKGTIKLVA 854 ++ +N G S + V E P ++ + PP+F+ + V + + Sbjct: 500 SILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLKLHNVPKGYECYMSC 559 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 VT NP P ITWYRN+ ++ + L+I V + D G+Y +A N+ G+ Sbjct: 560 AVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPK-DMGEYTIMAENTLGR 618 Query: 915 SSHGARVTIDVEKV 928 + + + E + Sbjct: 619 AESATVLNVKGENM 632 Score = 70.9 bits (166), Expect = 4e-10 Identities = 46/187 (24%), Positives = 88/187 (47%), Gaps = 8/187 (4%) Query: 1834 TYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNG 1893 T + +I +NE G + + ++T+ +PP P +ES++ V +W P+ +G Sbjct: 67 TGEIKIKLKNEHGVT---EAISQLTVLDKPSPPLGPAE--TTESSATCVEFRWRPPKDDG 121 Query: 1894 GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE 1953 GSP+++Y++E + V +W K+ + G V + ++ + +RI A G S E Sbjct: 122 GSPVSHYVMERQQVGRNTWKKMGVIPG-VPTYRDTDVDHGRKYCYRIWAVTAEGTSEMME 180 Query: 1954 SQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 + ++ A P PP P+ + + + +W P GG+ +LGY + R +W Sbjct: 181 TDEMQAGTLA-FPGPPAPPVVVSAF-DDCINLAWEAPSNRGGSRILGYILEKRKKGSNLW 238 Query: 2014 MEVGKVD 2020 + D Sbjct: 239 STINAAD 245 Score = 66.9 bits (156), Expect = 6e-09 Identities = 39/179 (21%), Positives = 78/179 (43%), Gaps = 2/179 (1%) Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVEN 1352 + + ++K G + + + +W + + + + + + L + + + Sbjct: 5 FTQAVKVKAGQNAIFKMQFVGQDPIKVQWYREGEELLNDTNVRVEKCTSQSRLLLSRCQR 64 Query: 1353 TDAGIYKLRLENNCGHADVEMNVTILDKPSPP-GKPNILEIDSSSINICWDEPENTGNST 1411 D G K++L+N G + +T+LDKPSPP G E ++ + W P++ G S Sbjct: 65 KDTGEIKIKLKNEHGVTEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSP 124 Query: 1412 IIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + +YV+E Q++ W + I T ++ Y +R +AV S+ ET E Sbjct: 125 VSHYVMERQQVGRNTWKKMGVIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTSEMMETDE 183 Score = 66.1 bits (154), Expect = 1e-08 Identities = 68/315 (21%), Positives = 115/315 (36%), Gaps = 25/315 (7%) Query: 1379 DKPSPPGKPNILEIDSSSIN---ICWDEPENTGN--STIIYYVVEYQEIDTTEW--ISVK 1431 D PPGK L+ +S + W +PE Y ++ ++ D+ EW + Sbjct: 321 DPKKPPGKVIGLKTSETSYTHFVLTWTKPEEKPGIQDEARGYFIDIRQADSIEWSRCNTS 380 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 + T S++ LK Y R A N+ A E +Y + T K + Sbjct: 381 PLITTSFSVKGLKPMDMYWVRVTASNDGGDGPAEEMDKYIIAMPRPVRPKFTNHKMKSFM 440 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX---XXXXXXXXXY 1548 + + +T F P P + W +D + T + T N Y Sbjct: 441 VVKAGNSVRITLHFEASPLPVIMWLKDNVPV-TKRVTISNSDSSSQLLIPSSERSDSGIY 499 Query: 1549 KCIAFNDHGEVETSCVVGIQQKPVITI---SNEDIK---------QKHKV--GDEWLVTA 1594 + N G+ S V + ++ V + + D++ + H V G E ++ Sbjct: 500 SILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLKLHNVPKGYECYMSC 559 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 + G P P + WY+N L D Y I+ + I ++ +YTI A NT G + Sbjct: 560 AVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPKDMGEYTIMAENTLGRA 619 Query: 1655 SVEVTLKVYDKPSKP 1669 L V + +P Sbjct: 620 ESATVLNVKGENMQP 634 Score = 63.3 bits (147), Expect = 7e-08 Identities = 58/215 (26%), Positives = 93/215 (43%), Gaps = 23/215 (10%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T K V G+ + + A P P I WL + IS + S S Sbjct: 432 TNHKMKSFMVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTISNSDSS------SQ 485 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT-------GEKE-----PPQVIEPLK 742 L I + ++ G Y+++ N G+ + + +++ K+ PP + PLK Sbjct: 486 LLIPSSERSDSGIYSILLKNLAGQETFSLEVRVTERFVTSTPARKDRDLQCPPVFVVPLK 545 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDE 800 V +G +S V GNP+P ITW +N+ + +T + L +V KD Sbjct: 546 LHNVPKGYECYMSCAVTGNPKPRITWYRNHISLNTDTNYYISNTCGVCSLLILQVGPKDM 605 Query: 801 GVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 G YT+ AEN+ G AE++ V+ V+ EN +P F Sbjct: 606 GEYTIMAENTLGRAESATVLNVK---GENMQPIQF 637 Score = 61.3 bits (142), Expect = 3e-07 Identities = 48/163 (29%), Positives = 66/163 (40%), Gaps = 4/163 (2%) Query: 1755 SEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK-W 1813 +E I T LD PS V W P + +GGSP+ Y +E +Q G+ W Sbjct: 81 TEAISQLTVLDKPSPPLGPAETTESSATCVEFRWRPPKDDGGSPVSHYVMERQQVGRNTW 140 Query: 1814 KXXXXX-XXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNF 1872 K R + Y +RI+A GTS D++ G TL P P Sbjct: 141 KKMGVIPGVPTYRDTDVDHGRKYCYRIWAVTAEGTS-EMMETDEMQAG-TLAFPGPPAPP 198 Query: 1873 VVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 VV + + L W P + GGS I YI+E + W+ I Sbjct: 199 VVVSAFDDCINLAWEAPSNRGGSRILGYILEKRKKGSNLWSTI 241 Score = 61.3 bits (142), Expect = 3e-07 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 3/93 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD-NVATL 568 P+FV L+ + P G C V G P+P+ITW+R I + D Y + V +L Sbjct: 538 PVFVVPLKLHNVPKGYECYMSCAVTGNPKPRITWYRNH--ISLNTDTNYYISNTCGVCSL 595 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +I +V P+D G +T +A+N G A S T L V+ Sbjct: 596 LILQVGPKDMGEYTIMAENTLGRAESATVLNVK 628 Score = 55.2 bits (127), Expect = 2e-05 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 6/131 (4%) Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 + + KD +I +N GV+ SQ L+K PSPP P E + V Sbjct: 59 LSRCQRKDTGEIKIKLKNEHGVT-EAISQLTVLDK----PSPPLGPAETTESSATCVEFR 113 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ DGG+P+ Y + + V + W ++G + + D+ Y RI+A Sbjct: 114 WRPPKDDGGSPVSHYVMERQQVGRNTWKKMGVIP-GVPTYRDTDVDHGRKYCYRIWAVTA 172 Query: 2047 IGLSEPLESDE 2057 G SE +E+DE Sbjct: 173 EGTSEMMETDE 183 Score = 49.2 bits (112), Expect = 0.001 Identities = 51/213 (23%), Positives = 81/213 (38%), Gaps = 21/213 (9%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G++V+ E P P I W + + + D+ + L+I D+G ++ Sbjct: 445 GNSVRITLHFEASPLPVIMWLKDNVPVTKRVTIS---NSDSSSQLLIPSSERSDSGIYSI 501 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 + KN AG + + E+ V +E V PP F K Sbjct: 502 LLKNLAGQETFSLEVRV--------TERFVTSTPARKDRDLQC------PPVFVVPLKLH 547 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 V +G + + C + P+P I W + D N + S+ CS+L I V Sbjct: 548 NVPKGYECYMSCAVTGNPKPRITWYRNHISLNTDTNYYI---SNTCGVCSLL-ILQVGPK 603 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 G YT++A N G A VL +K +P Q Sbjct: 604 DMGEYTIMAENTLGRAESATVLNVKGENMQPIQ 636 Score = 44.4 bits (100), Expect = 0.035 Identities = 18/59 (30%), Positives = 30/59 (50%) Query: 1372 EMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 EM L P PP P ++ IN+ W+ P N G S I+ Y++E ++ + W ++ Sbjct: 183 EMQAGTLAFPGPPAPPVVVSAFDDCINLAWEAPSNRGGSRILGYILEKRKKGSNLWSTI 241 Score = 41.1 bits (92), Expect = 0.33 Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 +K G+ V + + ++A P P W+ ++ + K + T + DS S+ L I E +D+GIY Sbjct: 442 VKAGNSVRITLHFEASPLPVIMWLKDNVPVTK-RVTISNSDS-SSQLLIPSSERSDSGIY 499 Query: 1359 KLRLENNCGHADVEMNVTILDK 1380 + L+N G + V + ++ Sbjct: 500 SILLKNLAGQETFSLEVRVTER 521 Score = 38.7 bits (86), Expect = 1.7 Identities = 26/115 (22%), Positives = 44/115 (38%), Gaps = 2/115 (1%) Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGG 1894 Y+FR+ A N G + + + PP + SE++ L WT+PE G Sbjct: 295 YEFRVTAVNLSGPGECSSPSEFVFARDPKKPPGKVIGLKTSETSYTHFVLTWTKPEEKPG 354 Query: 1895 --SPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 Y I+ + W++ T ++ +K D R++A N G Sbjct: 355 IQDEARGYFIDIRQADSIEWSRCNTSPLITTSFSVKGLKPMDMYWVRVTASNDGG 409 Score = 37.5 bits (83), Expect = 4.0 Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 5/99 (5%) Query: 833 PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 P F N + + VK ++++ +P+P I W ++N ++ TI+ N D + +L Sbjct: 429 PKFTNHKMKSFMVVKAGNSVRITLHFEASPLPVIMWLKDNVPVTKRVTIS-NSDSSS-QL 486 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 +I + + DSG Y + N AG+ + V + VT Sbjct: 487 LIPSSERS-DSGIYSILLKNLAGQETFSLEVRVTERFVT 524 >UniRef50_UPI0000F2E6F1 Cluster: PREDICTED: similar to L1 cell adhesion molecule; n=1; Monodelphis domestica|Rep: PREDICTED: similar to L1 cell adhesion molecule - Monodelphis domestica Length = 1344 Score = 101 bits (242), Expect = 2e-19 Identities = 170/781 (21%), Positives = 303/781 (38%), Gaps = 57/781 (7%) Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 RG + L + FP P +W S ++ + T + + +L + +VE D G Y+ Sbjct: 344 RGQPLVLECIAEGFPTPTIKWSYPSNQMQAGRVTYQNFNK---TLRLVRVEEEDDGEYRC 400 Query: 1361 RLENNCGHADVEMNVTILDKPSPPGKPNILEI---DSSSINICWDEPENTGNSTIIYYVV 1417 EN G A VT+ P +P L + +++ +N C + T V Sbjct: 401 WAENTLGSAQHVYYVTVEAAPYWLQEPESLVLAPGETARLN-CQVQGRPRPMVTWRINGV 459 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIK-E 1476 + + + + V+ + N++ N + + A N+ + A+ Y V++ Sbjct: 460 SLENLTRDDKLRVQG---GALILSNVQPNDTMVTQCEARNKHGLLLANA---YISVVQLP 513 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY-RD-GKKLKTAKATYENRXX 1534 TKI +P K + + L C GVP P + W RD L+ + Sbjct: 514 TKILTPD-NKTYREVQ---GSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGT 569 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNED--IKQKHKVGDEWLV 1592 Y C A ND V + +++ I ED +K+ V LV Sbjct: 570 LAIRDLQTNDTGSYFCQADNDQNRVSIKAHLQVKEATQIKKGPEDRTVKKGSNVNFPCLV 629 Query: 1593 TAVIEGIPPPEVIWYKNGNKLEND-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + + ++ WY N +++ KE KE+ + I L + Y+ A Sbjct: 630 S--FDPSLNIQIDWYWNDQNIKDFYKEDKYLIKEEE--LTIISLDYADQGNYSCVAKTAL 685 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP--D 1709 + + T+ V P P G + + + V + W P ++ + KY IE + + Sbjct: 686 DSVEKKATVLVVGSPG-PVGQLELYKQKDFHVQLSWSPA-EEHNSPIEKYNIEFEDRTME 743 Query: 1710 NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPS 1768 W +A V + ET KL+ Y FRVIA N G SE + +SEP + T VP Sbjct: 744 PGTWYPLATVPGN-ETSTRLKLSPFVHYNFRVIANNKFGASEPSPDSEPFI--TPKSVPE 800 Query: 1769 XXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI 1826 + ++ ITW P + + P + Y+V+ +Q+ + +W+ + Sbjct: 801 KNPTNVKGEGNETNNMVITWKPLKWIDWNGPELKYRVQWRQKNESEWREVMVRASKYV-V 859 Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE-STSRSVTLK 1885 Y+ ++ A NE+G D I IG + Q V E + +V +K Sbjct: 860 SNTPTFVPYEIKVQAINEVGKG----PDPHIVIGYSGEDVPQAIPIVAIELLNATTVRIK 915 Query: 1886 WTEPESN------GGSPITNYIIEFKTVKGKSWT--KIVTVGGSVHEHCIENIKEKDEII 1937 W + N G +T + + + + K T I+ S E + +++ I Sbjct: 916 WEPVDLNEVRGHLRGYRVTYWWVNSRWSRSKRHTPKTIIDKPASAMEAVLPDLRPYS--I 973 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 + + + SL S++++ E VP P + L +R + + SW P + Sbjct: 974 YSVHVQVFNSRSLGPPSETIKFETEEGVPDRPQS-LNLRRLSDTALQLSW-RPPLNPNGE 1031 Query: 1998 LLGYNIAIRDVT-KTMWMEVGK-VDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 L GY + R + E+ + + TL FN+ DL Y ++ A ++G E + Sbjct: 1032 LKGYQLIYRPFNQEPEENEMTEFLPPTTLMFNLSDLKPQTLYRFQLRATTKVGPGEMITQ 1091 Query: 2056 D 2056 + Sbjct: 1092 E 1092 Score = 75.4 bits (177), Expect = 2e-11 Identities = 93/397 (23%), Positives = 161/397 (40%), Gaps = 39/397 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G ++LEC P P I W + ++ V ++ + L++ V++ +G Sbjct: 345 GQPLVLECIAEGFPTPTIKWSYPSNQMQAGR---VTYQN----FNKTLRLVRVEEEDDGE 397 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y A N G A + + E P + EP +S+++ GE+ L+ QV G PRP +T Sbjct: 398 YRCWAENTLGSAQHVYYVTV---EAAPYWLQEP-ESLVLAPGETARLNCQVQGRPRPMVT 453 Query: 768 WCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 W N ++ L T+ D IL + D V +A N G+ +A I+V + Sbjct: 454 WRINGVSLENL-TRDDKLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQL 512 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY-RNNEIISPSETITQNFD 884 + P ++E+ + T L+ P+PSI W R+ + E + Sbjct: 513 PTKILTPD--NKTYREV---QGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYAN 567 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGK 944 G L I ++ + D+G Y C A N + S + + V++ T +K + ++G Sbjct: 568 G---TLAIRDLQTN-DTGSYFCQADNDQNRVS--IKAHLQVKEATQIKKGPEDRTVKKGS 621 Query: 945 TVILECQTSH----TVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 V C S + WY N + I ++E + D G C+ Sbjct: 622 NVNFPCLVSFDPSLNIQIDWYWNDQNIKDF-YKEDKYLIKEEELTIISLDYADQGNYSCV 680 Query: 1001 VKD-----QETSTMLVVKETIPE---FIRKLQDFEVK 1029 K ++ +T+LVV P + K +DF V+ Sbjct: 681 AKTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQ 717 Score = 66.1 bits (154), Expect = 1e-08 Identities = 76/331 (22%), Positives = 141/331 (42%), Gaps = 21/331 (6%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIP-EPDIAWL-FKGEEIVPDENISVAIE 685 + EG P +K + V+EG ++L C A +P I W+ + I DE +++ Sbjct: 219 VAEGAPKWPKEKVQPFEVEEGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQN 278 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEP-- 740 +++ + +VL TN + R PI L++K P+++ P Sbjct: 279 GNLY-FANVL--TNDSHSDYICHAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEG 335 Query: 741 LKSMIVR-QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799 L S +V +G+ ++L G P PTI W + ++A ++ +++ ++ +D Sbjct: 336 LTSRLVALRGQPLVLECIAEGFPTPTIKWSYPSNQMQAGRVTYQNFNKTLRLVRVEE-ED 394 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 +G Y AEN+ G A+ +TVE P ++ + + + T +L +V Sbjct: 395 DGEYRCWAENTLGSAQHVYYVTVE-------AAPYWLQEPESLVLAPGETARLNCQVQGR 447 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P +TW R N + + T + L+++NV D+ +C A N G A Sbjct: 448 PRPMVTW-RINGVSLENLTRDDKLRVQGGALILSNVQPN-DTMVTQCEARNKHGLLLANA 505 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 +++ + K+Y +G T L C Sbjct: 506 YISVVQLPTKILTPDNKTYREVQGSTAYLLC 536 Score = 63.3 bits (147), Expect = 7e-08 Identities = 79/333 (23%), Positives = 134/333 (40%), Gaps = 27/333 (8%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP +++ P+ V DI+L+C PE W + P++ + + + Sbjct: 124 PPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGSF 183 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 +N + +GTY A NR G A S I L + K P + ++P + V +G+ Sbjct: 184 IITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAEGAPKWPKEKVQPFE---VEEGQ 240 Query: 751 SVILSAQVVGNP-RPTITWCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 SV+L + +P I W + + + +G+ + +L D Y Sbjct: 241 SVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTMGQNGNLYFANVLTNDSHSD---YIC 297 Query: 806 KAE--NSEGIAETSAVITVEEPTEE--NAEPPLFI-NRFQEITVKEKGTIKLVARVTRN- 859 A + I + + +PT P L + V +G ++ + Sbjct: 298 HAHFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECIAEGF 357 Query: 860 PVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P+I W Y +N++ + T QNF N L + V+ E D G+Y+C A N+ G + H Sbjct: 358 PTPTIKWSYPSNQMQAGRVTY-QNF---NKTLRLVRVEEE-DDGEYRCWAENTLGSAQHV 412 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 VT VE + +S G+T L CQ Sbjct: 413 YYVT--VEAAPYWLQEPESLVLAPGETARLNCQ 443 Score = 63.3 bits (147), Expect = 7e-08 Identities = 97/433 (22%), Positives = 176/433 (40%), Gaps = 36/433 (8%) Query: 1083 DEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVR 1138 D+GEY C + +A+ VE P + ++ + G A ++ + +V Sbjct: 394 DDGEYRCWAENTLGSAQHVYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVT 453 Query: 1139 WFKDGSEIQ-FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 W +G ++ + +L + G L + + +D CE N K +L S+ Sbjct: 454 WRINGVSLENLTRDDKLRVQGGA--LILSNVQPNDTMVTQCEARN-KHGLLLANAYISV- 509 Query: 1198 FTLRLPEFILVPAN--------TDAYLTVE---IPDETLDVTWYKKKSVIEDTEKFTLIS 1246 ++LP IL P N + AYL +P ++ + +V++D E+F + Sbjct: 510 --VQLPTKILTPDNKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQD-ERFVPYA 566 Query: 1247 DVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDV 1305 + TL IR +D Y C + ++ +K + V+ +I + +K+GS+V Sbjct: 567 N---GTLAIRDLQTNDTGSYFCQADNDQNRVSIKAHLQVKEATQIKKGPEDRTVKKGSNV 623 Query: 1306 TL--LVDYQAFPQPNDEWIVNSKIIKKC-KHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 LV + +W N + IK K K I K LTI ++ D G Y Sbjct: 624 NFPCLVSFDPSLNIQIDWYWNDQNIKDFYKEDKYLI--KEEELTIISLDYADQGNYSCVA 681 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE- 1421 + + + V ++ P P G+ + + + + W P NS I Y +E+++ Sbjct: 682 KTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQLSW-SPAEEHNSPIEKYNIEFEDR 740 Query: 1422 -IDTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 ++ W + + +TS + L Y FR A N+ S+ S +E + K Sbjct: 741 TMEPGTWYPLATVPGNETSTRLKLSPFVHYNFRVIANNKFGASEPSPDSEPFITPKSVPE 800 Query: 1480 QSPTVEKPLKNIT 1492 ++PT K N T Sbjct: 801 KNPTNVKGEGNET 813 Score = 57.2 bits (132), Expect = 5e-06 Identities = 61/293 (20%), Positives = 117/293 (39%), Gaps = 20/293 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + ++P++ + G L C++ P P + W G + EN++ + + + Sbjct: 421 PYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSL---ENLT--RDDKLRVQGG 475 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEP-LKSMIVRQGESV 752 L ++NV+ A N+ G + + + P +++ P K+ QG + Sbjct: 476 ALILSNVQPNDTMVTQCEARNKHGLLLANAYISV---VQLPTKILTPDNKTYREVQGSTA 532 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 L G P P+I W ++ + + ++ + D G Y +A+N + Sbjct: 533 YLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDTGSYFCQADNDQN 592 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS--ITWYRNN 870 A + V+E T+ P ++ TVK+ + V+ +P + I WY N+ Sbjct: 593 RVSIKAHLQVKEATQIKKGP-------EDRTVKKGSNVNFPCLVSFDPSLNIQIDWYWND 645 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + I + E EL I ++D D G+Y CVA + A V + Sbjct: 646 QNIKDFYKEDKYLIKEE-ELTIISLD-YADQGNYSCVAKTALDSVEKKATVLV 696 Score = 48.4 bits (110), Expect = 0.002 Identities = 124/598 (20%), Positives = 218/598 (36%), Gaps = 71/598 (11%) Query: 733 EPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNN---KPVKALPTKSDGDTHS 788 +PP + E + ++V + ++L + G P W K N P K L + ++ S Sbjct: 123 QPPNITEQSPEKLVVFPTDDIVLKCEASGKPEVQFRWTKENIHFSPEKELGATTHINSGS 182 Query: 789 ITILKPKK---VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVK 845 I + +G Y A N G A + + V E P + Q V+ Sbjct: 183 FIITGNTSNFAQRYQGTYRCFASNRLGTAMSHEIHLVAE-----GAPKWPKEKVQPFEVE 237 Query: 846 EKGTIKLVARVTRNPVPSITWYRNNEI--ISPSETITQNFDGENIELVITNVDSEIDSGD 903 E ++ L + V ++ N+ I I+ E +T G+N L NV + D Sbjct: 238 EGQSVVLPCNPPASAVQPRIYWMNSRIFHIAQDERVTM---GQNGNLYFANVLTNDSHSD 294 Query: 904 YKCVASNSAGKSSHGARVTIDVE------------KVTFVKHLQKSYETEEGKTVILEC- 950 Y C A + G + + ID+ ++ + L G+ ++LEC Sbjct: 295 YICHA-HFLGARTIMQKEPIDLRVKPTNNMIYRRPRLLLPEGLTSRLVALRGQPLVLECI 353 Query: 951 -QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTM 1009 + T + KW + + M + + D G +C ++ S Sbjct: 354 AEGFPTPTIKWSYPSNQ---MQAGRVTYQNFNKTLRLVRVEEEDDGEYRCWAENTLGSAQ 410 Query: 1010 ---LVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDF 1065 V E P ++++ + + + A L ++ +V W +G + + D Sbjct: 411 HVYYVTVEAAPYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRING--VSLENLTRDD 468 Query: 1066 EKRGHIRKLYIRNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQKVNKG 1121 + R L + N +D C R++ A ++VV+LP +I+T Sbjct: 469 KLRVQGGALILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQLPTKILT--------PD 520 Query: 1122 NKATFEIELTKGDALVRWF-KDGSEIQFSNHIQLTI--DGK-----KQKLKIYDCDLDDA 1173 NK E++ + L F IQ+ N Q T+ D + L I D +D Sbjct: 521 NKTYREVQGSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYANGTLAIRDLQTNDT 580 Query: 1174 GEYSCEVGNSK----CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI---PDETLD 1226 G Y C+ N + A L V+E + + PE V ++ + P + Sbjct: 581 GSYFCQADNDQNRVSIKAHLQVKEAT--QIKKGPEDRTVKKGSNVNFPCLVSFDPSLNIQ 638 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV 1284 + WY I+D K +K+ L I DQ Y+CV A + + K V+ Sbjct: 639 IDWYWNDQNIKDFYKEDKYL-IKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVL 695 Score = 45.6 bits (103), Expect = 0.015 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 8/136 (5%) Query: 1930 IKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV---PSP-PTAPLEIRMVGSNIVMT 1985 IKE++ I + + S ++ +EK ATV SP P LE+ V Sbjct: 659 IKEEELTIISLDYADQGNYSCVAKTALDSVEKKATVLVVGSPGPVGQLELYKQKDFHVQL 718 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKT--MWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 SW +P + +P+ YNI D T W + V N ++ LS Y R+ A Sbjct: 719 SW-SPAEEHNSPIEKYNIEFEDRTMEPGTWYPLATVPGNETSTRLK-LSPFVHYNFRVIA 776 Query: 2044 RNEIGLSEPLESDEPF 2059 N+ G SEP EPF Sbjct: 777 NNKFGASEPSPDSEPF 792 Score = 40.3 bits (90), Expect = 0.57 Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVAT 567 AP ++++ G T + CQV+G PRP +TW ++ ++D ++ Sbjct: 420 APYWLQEPESLVLAPGETARLNCQVQGRPRPMVTWRINGVSLENLTRDDKLRVQG---GA 476 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 L++ V P D C A+N G + + +V+ P Sbjct: 477 LILSNVQPNDTMVTQCEARNKHGLLLANAYISVVQLP 513 Score = 38.7 bits (86), Expect = 1.7 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC EG+P P I W + Q ++ Y + N TL + V ED G + C Sbjct: 345 GQPLVLECIAEGFPTPTIKWSYPS---NQMQAGRVTYQNFN-KTLRLVRVEEEDDGEYRC 400 Query: 584 VAKNAAGFASSTTELIVEA 602 A+N G A + VEA Sbjct: 401 WAENTLGSAQHVYYVTVEA 419 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 5/79 (6%) Query: 524 GSTVQFECQVEGYPRPQITWF-RQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 GST C G P P I W R A + + F Y + TL IR++ D G++ Sbjct: 529 GSTAYLLCNAFGVPMPSIQWLNRDQATVLQDERFVPYAN----GTLAIRDLQTNDTGSYF 584 Query: 583 CVAKNAAGFASSTTELIVE 601 C A N S L V+ Sbjct: 585 CQADNDQNRVSIKAHLQVK 603 >UniRef50_Q4RRT1 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1098 Score = 101 bits (242), Expect = 2e-19 Identities = 95/378 (25%), Positives = 156/378 (41%), Gaps = 26/378 (6%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 +I A SD G + V A+++ P ++P Q V E + +C + Sbjct: 175 MISHARKSDAGMYVCVGKNMVGERDSDPAELVVYERPVLVRRPVNQVVMEEDTVDFQCEV 234 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P P + W + E+ P + H ++L++ +VK+ EG YT + N G Sbjct: 235 HGDPAPTVRWRREEGEL-PRGRFEI------HNG-NILRLFHVKEEDEGMYTCTSENSVG 286 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA 777 + +L++ PPQ+ + I QG SV GNP P I W K + Sbjct: 287 KTEASAMLQVHV----PPQIATKPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLL 342 Query: 778 LPTK--SDGDTHSITI-----LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 P + S +S+++ + +D G Y +A + G + ++ V E N Sbjct: 343 FPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKVLLDV-EGGPSNR 401 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 PP+ T T++L RV P I+W +N E + +E EN L Sbjct: 402 IPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLM--ENGTL 459 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVIL 948 IT++ E DSG Y C+AS++ G+SS +T+ V + + + K V+ Sbjct: 460 QITDI-KETDSGTYTCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPVMT 518 Query: 949 ECQTSHTVSTKWYHNKKE 966 E T +TV+ W N E Sbjct: 519 EV-TKNTVTLTWQSNPHE 535 Score = 88.6 bits (210), Expect = 2e-15 Identities = 129/537 (24%), Positives = 211/537 (39%), Gaps = 58/537 (10%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL---PTKS----- 782 E PP++ E +IV +GE L+ + G P P I W K+ + V+ P Sbjct: 13 EDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLP 72 Query: 783 DGDTHSITILKPKKVK-DEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINRFQ 840 G + I+ ++ K DEGVYT A N G A + +A + V ++ + P + Sbjct: 73 SGSLFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDV---- 128 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 + E ++ V +P P + W RNN I + G+ L+I++ D Sbjct: 129 VVAAGEPAVLECVPP-RGHPEPIVFWKRNNVRIGSKDDRIAMRGGK---LMISHARKS-D 183 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT--SHTVST 958 +G Y CV N G+ + E+ V+ EE TV +C+ + Sbjct: 184 AGMYVCVGKNMVGERDSDPAELVVYERPVLVRRPVNQVVMEED-TVDFQCEVHGDPAPTV 242 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKE 1014 +W + E+ R I G D G+ C ++ E S ML V Sbjct: 243 RWRREEGELPR--GRFEIHNGNILRLFHVKEE--DEGMYTCTSENSVGKTEASAMLQV-H 297 Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVEINSETADVVWERDGE--IIKP-----KKNKYDFE 1066 P+ K +D + + V + + W+++G ++ P + +Y Sbjct: 298 VPPQIATKPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVS 357 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSC--ILRDESCTAEVTV-VE------LPPEIITRLQNQK 1117 G L I + D G Y C I S ++V + VE +PP I NQ Sbjct: 358 MSGD---LTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQT 414 Query: 1118 VNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 G + G ++ + W K+G E+ N +LT+ + L+I D D+G Y Sbjct: 415 ATLGATVQLHCRVIGGPSIHISWEKNGEELH-GNEARLTLM-ENGTLQITDIKETDSGTY 472 Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 +C G S + LTV E + T R+ EFI +P + E+ T+ +TW Sbjct: 473 TCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPVMTEVTKNTVTLTW 529 Score = 87.0 bits (206), Expect = 5e-15 Identities = 117/481 (24%), Positives = 193/481 (40%), Gaps = 56/481 (11%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF-----DGE 886 PP ++ V + L + P P I WY++ E + ++ G Sbjct: 16 PPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLPSGS 75 Query: 887 NIEL-VITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGK 944 L ++ S+ D G Y CVA N G++ S A + + + + F + G+ Sbjct: 76 LFFLRIVHGRRSKPDEGVYTCVARNYLGEAVSRNASLDVAILRDDF-RQAPSDVVVAAGE 134 Query: 945 TVILEC--QTSHTVSTK-WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 +LEC H W N I D R ++ G+ D G+ C+ Sbjct: 135 PAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMISHARKS---DAGMYVCVG 191 Query: 1002 KDQ-----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERD-GE 1054 K+ LVV E P +R+ + V E+D + E++ + A V W R+ GE Sbjct: 192 KNMVGERDSDPAELVVYER-PVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGE 250 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIIT 1111 + + +++ G+I +L+ + DEG Y+C + E + V +PP+I T Sbjct: 251 L---PRGRFEIHN-GNILRLF--HVKEEDEGMYTCTSENSVGKTEASAMLQVHVPPQIAT 304 Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGK-----KQKLKI 1165 + ++Q +G TFE T + W K+GS++ + G+ L I Sbjct: 305 KPRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTI 364 Query: 1166 YDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL--TV 1218 D +D+G Y C+ G+ +L VE N R+P I PAN A L TV Sbjct: 365 TDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSN---RIPPIIRQGPANQTATLGATV 421 Query: 1219 E-----IPDETLDVTWYKKKSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 + I ++ ++W K + E + TL ++ TL I E D YTC+ Sbjct: 422 QLHCRVIGGPSIHISWEKNGEELHGNEARLTL---MENGTLQITDIKETDSGTYTCIASS 478 Query: 1273 A 1273 A Sbjct: 479 A 479 Score = 78.6 bits (185), Expect = 2e-12 Identities = 108/488 (22%), Positives = 178/488 (36%), Gaps = 52/488 (10%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD----ENISVAIE 685 E PP ++ P V +G L C+ P P I W GE + D + + + Sbjct: 13 EDSPPRIAEDPSDLIVSKGEPATLNCKAEGRPTPIIEWYKDGERVETDRDDPRSHRMLLP 72 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-----ASLPIVLKIKTGEKEPPQVIEP 740 S + ++ K EG YT VA N GE ASL + + ++ ++ P Sbjct: 73 SGSLFFLRIVHGRRSKP-DEGVYTCVARNYLGEAVSRNASLDVAI-LRDDFRQAP----- 125 Query: 741 LKSMIVRQGESVILS-AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799 ++V GE +L G+P P + W +NN + + + + I +K D Sbjct: 126 -SDVVVAAGEPAVLECVPPRGHPEPIVFWKRNNVRIGSKDDRIAMRGGKLMISHARK-SD 183 Query: 800 EGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 G+Y +N G ++ V E P+ + R V E+ T+ V + Sbjct: 184 AGMYVCVGKNMVGERDSDPAELVV------YERPVLVRRPVNQVVMEEDTVDFQCEVHGD 237 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P++ W R E F+ N ++ E D G Y C + NS GK+ A Sbjct: 238 PAPTVRWRREE-----GELPRGRFEIHNGNILRLFHVKEEDEGMYTCTSENSVGKTEASA 292 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKEISGMDHREIIQ 977 + + V K + +G++V EC T+ + W ++ + Q Sbjct: 293 MLQVHVPPQIATK--PRDQIATQGRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQ 350 Query: 978 EGRXXXXXXXXXXXXDV-----GVIKCIVKDQETSTMLVV--------KETIPEFIRKLQ 1024 GR DV G C S M V IP IR+ Sbjct: 351 SGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGP 410 Query: 1025 DFEVKEKDVAI-LEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 + + L I + + WE++GE + + + + G ++ I+ T Sbjct: 411 ANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLMENGTLQITDIKET--- 467 Query: 1083 DEGEYSCI 1090 D G Y+CI Sbjct: 468 DSGTYTCI 475 Score = 70.5 bits (165), Expect = 5e-10 Identities = 86/365 (23%), Positives = 148/365 (40%), Gaps = 48/365 (13%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+ V + + + TV F+C+V G P P + W R+ + P F+++ + N+ L Sbjct: 211 PVLVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGEL-PRGRFEIH--NGNILRLF 267 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 V ED G +TC ++N+ G ++ L V P + + Sbjct: 268 --HVKEEDEGMYTCTSENSVGKTEASAMLQVHVP-------PQIATKPRDQIATQGRSVT 318 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 T + P + EGS +L LF G+ SV++ D Sbjct: 319 FECGTTGNPPPAIFWQKEGSQML---------------LFPGQPPSQSGRYSVSMSGD-- 361 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTG--EKEPPQVIEPLKSMIVR 747 L IT+V G Y A++ G ++L ++ G + PP + + + Sbjct: 362 -----LTITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTAT 416 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYT 804 G +V L +V+G P I+W KN + + +A T + T IT +K D G YT Sbjct: 417 LGATVQLHCRVIGGPSIHISWEKNGEELHGNEARLTLMENGTLQITDIKE---TDSGTYT 473 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A ++ G + S +TV E + I+ F ++ + + + VT+N V ++ Sbjct: 474 CIASSATGESSWSGTLTVREYGVYSTSR---ISEFIQLPGPPQKPV--MTEVTKNTV-TL 527 Query: 865 TWYRN 869 TW N Sbjct: 528 TWQSN 532 Score = 69.7 bits (163), Expect = 8e-10 Identities = 74/302 (24%), Positives = 121/302 (40%), Gaps = 34/302 (11%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL---------KTAKATYENRXXXX 1536 KP I T+ + C G P P + W ++G ++ ++ + + Sbjct: 305 KPRDQIATQ-GRSVTFECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLT 363 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS----NEDIKQKHKVGDEWLV 1592 Y C A + G V + ++ ++ P I Q +G + Sbjct: 364 ITDVHPEDSGFYICQAISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQL 423 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + G P + W KNG +L + E +T E ++I ++K + S YT AS+ G Sbjct: 424 HCRVIGGPSIHISWEKNGEELHGN-EARLTLMEN-GTLQITDIKETDSGTYTCIASSATG 481 Query: 1653 TSSVEVTLKVYDK--------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 SS TL V + P P+ PV M E+++ +VT+ W+ +GG + Sbjct: 482 ESSWSGTLTVREYGVYSTSRISEFIQLPGPPQKPV-MTEVTKNTVTLTWQSNPHEGGAAV 540 Query: 1699 TKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SE 1756 T Y IE + W VAD + E + + L N Y+F V A N G S+ SE Sbjct: 541 TSYIIEAFSQSVGSTWQTVADHVKQ-ERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599 Query: 1757 PI 1758 P+ Sbjct: 600 PV 601 Score = 61.3 bits (142), Expect = 3e-07 Identities = 109/522 (20%), Positives = 201/522 (38%), Gaps = 57/522 (10%) Query: 993 DVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE-VEINSETAD 1046 D GV C+ ++ + L V +F + D V + A+LE V Sbjct: 90 DEGVYTCVARNYLGEAVSRNASLDVAILRDDFRQAPSDVVVAAGEPAVLECVPPRGHPEP 149 Query: 1047 VV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD-----ESCTAEV 1100 +V W+R+ I K ++ RG KL I + D G Y C+ ++ +S AE+ Sbjct: 150 IVFWKRNNVRIGSKDDR--IAMRGG--KLMISHARKSDAGMYVCVGKNMVGERDSDPAEL 205 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGK 1159 V E P ++ R NQ V + + F+ E+ A VRW ++ E+ ++ Sbjct: 206 VVYERPV-LVRRPVNQVVMEEDTVDFQCEVHGDPAPTVRWRREEGELP-RGRFEIH---N 260 Query: 1160 KQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 L+++ +D G Y+C VG ++ +A+L V P + + I + + Sbjct: 261 GNILRLFHVKEEDEGMYTCTSENSVGKTEASAMLQVHVPP-QIATKPRDQIATQGRSVTF 319 Query: 1216 LTVEIPDETLDVTWYKKKSVI-----EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 + + W K+ S + + + S L I +D Y C Sbjct: 320 ECGTTGNPPPAIFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQA 379 Query: 1271 LDAKSTTKLKVEV-VE------FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 + + KV + VE PP I G+ V L P + W Sbjct: 380 ISVAGSVMSKVLLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEK 439 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI------ 1377 N + + + +++ +L I ++ TD+G Y + G + +T+ Sbjct: 440 NGEELHGNEARLTLMEN--GTLQITDIKETDSGTYTCIASSATGESSWSGTLTVREYGVY 497 Query: 1378 --------LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEW 1427 + P PP KP + E+ +++ + W + G + + Y++E Q + +T Sbjct: 498 STSRISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQ 557 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ + + ++ L N+ Y F AVN +SD S +E Sbjct: 558 TVADHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISE 599 Score = 57.6 bits (133), Expect = 4e-06 Identities = 82/391 (20%), Positives = 139/391 (35%), Gaps = 34/391 (8%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXX 1543 V +P+ + E + ++ C G P P V W R+ +L + N Sbjct: 214 VRRPVNQVVME-EDTVDFQCEVHGDPAPTVRWRREEGELPRGRFEIHNGNILRLFHVKEE 272 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 Y C + N G+ E S ++ + P I D Q G G PPP Sbjct: 273 DEGMYTCTSENSVGKTEASAMLQVHVPPQIATKPRD--QIATQGRSVTFECGTTGNPPPA 330 Query: 1604 VIWYKNGNKL-----ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 + W K G+++ + + + + + I ++ S Y +A + AG+ +V Sbjct: 331 IFWQKEGSQMLLFPGQPPSQSGRYSVSMSGDLTITDVHPEDSGFYICQAISVAGSVMSKV 390 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKPPLD---DGG----LELTKYAIEKHEPD-- 1709 L V PS P+I + + ++ T+ L GG + K E H + Sbjct: 391 LLDVEGGPSNRIPPIIRQGPANQTATLGATVQLHCRVIGGPSIHISWEKNGEELHGNEAR 450 Query: 1710 ----NNRWIKVADV-DRDVETY-CIQKLNENCEYMFRVIAQNPVG-FSEALESEPIVIKT 1762 N +++ D+ + D TY CI + G +S + SE I + Sbjct: 451 LTLMENGTLQITDIKETDSGTYTCIASSATGESSWSGTLTVREYGVYSTSRISEFIQLPG 510 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI--KQEGKKWKXXXXXX 1820 P + +V +TW + GG+ + Y +E + G W+ Sbjct: 511 PPQKP-------VMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQTVADHV 563 Query: 1821 XXXAR-IQKLSINTTYQFRIYARNEIGTSLP 1850 + L NT Y F + A N G S P Sbjct: 564 KQERHTVVGLFPNTVYLFIVRAVNSYGLSDP 594 Score = 48.8 bits (111), Expect = 0.002 Identities = 31/104 (29%), Positives = 51/104 (49%), Gaps = 3/104 (2%) Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVT 1917 I + + P P+ V++E T +VTL W GG+ +T+YIIE F G +W + V Sbjct: 502 ISEFIQLPGPPQKPVMTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTW-QTVA 560 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLE 1960 H + + +F + A N+ G+S P+ S+ VR + Sbjct: 561 DHVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISEPVRTQ 604 Score = 44.4 bits (100), Expect = 0.035 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 3/108 (2%) Query: 1958 RLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEV 2016 R+ + +P PP P+ + V N V +W + +GGA + Y I A + W V Sbjct: 501 RISEFIQLPGPPQKPV-MTEVTKNTVTLTWQSNPHEGGAAVTSYIIEAFSQSVGSTWQTV 559 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPG 2064 V + + L N Y+ + A N GLS+P EP + G Sbjct: 560 AD-HVKQERHTVVGLFPNTVYLFIVRAVNSYGLSDPSPISEPVRTQDG 606 >UniRef50_Q4SR22 Cluster: Chromosome 11 SCAF14528, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 11 SCAF14528, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1154 Score = 101 bits (241), Expect = 3e-19 Identities = 126/514 (24%), Positives = 206/514 (40%), Gaps = 56/514 (10%) Query: 629 LEGIPPTFSKKPKAQY----VDEGSDILLECRLV-AIPEPDIAWL-FKGEEIVPDENISV 682 +E I P K PK V+EG +L+C IP I W+ + I DE +S Sbjct: 95 IEFIVPNVPKFPKETIDPVVVEEGQPFVLKCNPPDGIPPLQIYWMTISLQHIEQDERVST 154 Query: 683 AIESDMHM-----------YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE 731 ++ D++ YC ++ + T V V + +AS + I + Sbjct: 155 SLNGDLYFSHAVDKDSRRDYCCFAAFPRIRTIVQKTAMSVIVKTKKDASPEVANAIL--Q 212 Query: 732 KEPPQVIEPLKSMIVR--QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSI 789 + P + P R +GE + L G P P + W K + LPTK+ ++H Sbjct: 213 RRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKMGQ---RLPTKATIESHGK 269 Query: 790 TILKPK-KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRF-QEITVKEK 847 + P + +D G Y KA+N+ G A +TVE P E +EP ++ ++ +K Sbjct: 270 LLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIGSDVLIK-- 327 Query: 848 GTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCV 907 V+ P P++TW N + S + G+ I L T DS Y+C Sbjct: 328 ------CSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPS---DSAVYQCE 378 Query: 908 ASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEI 967 ASN G A + I + + Y EGK V++ C+ + S +K + Sbjct: 379 ASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDT 438 Query: 968 SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETST----MLVVKETI-----PE 1018 S D G C K+ E S+ ML VK+ PE Sbjct: 439 SDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPE 498 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK--KNKYDFEKRGHIRKLYI 1076 R L+ + +A + +++ +++WE+D + I +N F + G L I Sbjct: 499 DSRILKGTTAQFSCLAEYDKSFSNDF-EILWEKDDKEIAVNYTENSRYFVEDG---LLQI 554 Query: 1077 RNTSVHDEGEYSCILR----DESCTAEVTVVELP 1106 N S D+G Y+C+ R + TA + V+++P Sbjct: 555 VNVSHLDKGVYTCLARTPMDGDKATALLLVIDVP 588 Score = 94.7 bits (225), Expect = 2e-17 Identities = 101/427 (23%), Positives = 177/427 (41%), Gaps = 41/427 (9%) Query: 639 KPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 K +A+ V +G D+ LEC P P + W+ G+ + P + IES + +L + Sbjct: 224 KSEARLV-KGEDLNLECIAAGFPTPQVEWVKMGQRL-PTK---ATIES----HGKLLFVP 274 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 V++ G Y A N GEA + ++ PP+ + +S + G V++ V Sbjct: 275 TVEQEDGGKYMCKAKNTLGEAVHYFTVTVEG----PPEWVSEPESQLSMIGSDVLIKCSV 330 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 G P+PT+TW N ++ P + +L K D VY +A N G ++A Sbjct: 331 SGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNRHGTLLSNA 390 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 I + N P + ++ + E + + +V +P P+ITW +++ S Sbjct: 391 NIMI-----MNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGP 445 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSY 938 D +E I + E D+G Y C A N+ G S+ A + V+ T + + Sbjct: 446 RFSVHDNGTLE--IYRAEKE-DAGPYTCFAKNTEGSSAINA--MLSVKDPTRIVEPPEDS 500 Query: 939 ETEEGKTVILECQTSHTVSTK------WYHNKKEIS---GMDHREIIQEGRXXXXXXXXX 989 +G T C + S W + KEI+ + R +++G Sbjct: 501 RILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDG---LLQIVNV 557 Query: 990 XXXDVGVIKCIVK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV---EINSE 1043 D GV C+ + D + +T L++ +P+ + L E K K V + + + NS Sbjct: 558 SHLDKGVYTCLARTPMDGDKATALLLVIDVPDAPQYLVLSEHKSKSVKLKWIPGDDHNSS 617 Query: 1044 TADVVWE 1050 T + + E Sbjct: 618 TTEFIIE 624 Score = 74.9 bits (176), Expect = 2e-11 Identities = 57/193 (29%), Positives = 82/193 (42%), Gaps = 11/193 (5%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX-XXXXXXXXXYKCIAFND 1555 ED+ L CI G P P+V W + G++L T KAT E+ Y C A N Sbjct: 233 EDLNLECIAAGFPTPQVEWVKMGQRLPT-KATIESHGKLLFVPTVEQEDGGKYMCKAKNT 291 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 GE V ++ P +E Q +G + L+ + G P P V W NGN+L++ Sbjct: 292 LGEAVHYFTVTVEGPPEWV--SEPESQLSMIGSDVLIKCSVSGTPQPTVTWRVNGNRLQD 349 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIM 1675 N T V+ K S S+ Y EASN GT + + + P P+I+ Sbjct: 350 SPAPNRRVLGDTIVLH--NTKPSDSAVYQCEASNRHGTLLSNANIMIMNFP-----PMIL 402 Query: 1676 REISRESVTIEWK 1688 E + +E K Sbjct: 403 TENDEDYSAVEGK 415 Score = 74.5 bits (175), Expect = 3e-11 Identities = 122/607 (20%), Positives = 220/607 (36%), Gaps = 42/607 (6%) Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 E R+ +G D+ L FP P EW+ + + TK +I+S L + VE D Sbjct: 226 EARLVKGEDLNLECIAAGFPTPQVEWVKMGQRLP----TKATIESHGKLLFVPTVEQEDG 281 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEIDSSSINICWDEPENTGNSTII 1413 G Y + +N G A VT+ P +P + I S + C T T+ Sbjct: 282 GKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSMIGSDVLIKC--SVSGTPQPTVT 339 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 + V + D+ + + + N K + S AV + + S+ T Sbjct: 340 WRVNGNRLQDSP--APNRRVLGDTIVLHNTKPSDS------AVYQCEASNRHGTLLSNAN 391 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD--GKKLKTAKATYEN 1531 I + + ++ + + + + C P P +TW +D + + + + Sbjct: 392 IMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSVDGPRFSVHD 451 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C A N G + ++ ++ I ED + ++ Sbjct: 452 NGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFS 511 Query: 1592 VTAVIEG--IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 A + E++W K+ ++ + N + +++I + YT A Sbjct: 512 CLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNVSHLDKGVYTCLART 571 Query: 1650 TAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP- 1708 L V D P P+ +++ E +SV ++W P DD T++ IE E Sbjct: 572 PMDGDKATALLLVIDVPDAPQ-YLVLSEHKSKSVKLKWIPG-DDHNSSTTEFIIEYEESQ 629 Query: 1709 -DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALDV 1766 + W ++ V + I KL+ + +Y FRV N VG S+P +T Sbjct: 630 REPGNWKELLRVPGN-HNSAILKLHGHVDYCFRVSGVNAVG--RGPSSQPTERYRTPPAA 686 Query: 1767 PSXXXXXXXXXXIDNESVYITW---FPSEKNGGSPIIDYKVEIKQEG--KKWKXXXXXXX 1821 P + I W P E+NG P ++YKV +++ + W+ Sbjct: 687 PDKNPENIKIESHLPHEMDINWEPLLPIEQNG--PGLEYKVSYRRQDVEEDWQEHIVKRH 744 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLT--PPSQPRNFVVSESTS 1879 ++ Y+ +I ARN G + + +I G + P + P + V S Sbjct: 745 SFV-VKNTPTFVPYEIKIQARNHQG----WGPEPRIATGYSGEDFPSAAPDDVAVEVINS 799 Query: 1880 RSVTLKW 1886 V + W Sbjct: 800 SVVKVSW 806 Score = 72.9 bits (171), Expect = 9e-11 Identities = 101/505 (20%), Positives = 185/505 (36%), Gaps = 36/505 (7%) Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXX--XXXXXYKCIAFND 1555 D+ + C G PQP VTW +G +L+ + A Y+C A N Sbjct: 323 DVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGDTIVLHNTKPSDSAVYQCEASNR 382 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 HG + ++ + I P + ++ D G ++ + P P + W K+ Sbjct: 383 HGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHCKVFSSPSPTITWSKDDTSDSV 442 Query: 1616 D-KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 D +++ + I ++ + YT A NT G+S++ L V D E P Sbjct: 443 DGPRFSV---HDNGTLEIYRAEKEDAGPYTCFAKNTEGSSAINAMLSVKDPTRIVEPPED 499 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR-DVETYCIQKLNE 1733 R + + T ++ + + I + D + + R VE +Q +N Sbjct: 500 SRIL--KGTTAQFSCLAEYDKSFSNDFEILWEKDDKEIAVNYTENSRYFVEDGLLQIVNV 557 Query: 1734 N--CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 + + ++ +A+ P+ +A + +DVP ++SV + W P Sbjct: 558 SHLDKGVYTCLARTPMDGDKA-----TALLLVIDVPDAPQYLVLSEH-KSKSVKLKWIPG 611 Query: 1792 EKNGGSP---IIDYKVEIKQEGKKWKXXXXX-XXXXARIQKLSINTTYQFRIYARNEIGT 1847 + + S II+Y+ E ++E WK + I KL + Y FR+ N +G Sbjct: 612 DDHNSSTTEFIIEYE-ESQREPGNWKELLRVPGNHNSAILKLHGHVDYCFRVSGVNAVGR 670 Query: 1848 SLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----ESNGGSPITNYIIE 1903 P + + P P N + + + W EP E NG P Y + Sbjct: 671 G-PSSQPTERYRTPPAAPDKNPENIKIESHLPHEMDINW-EPLLPIEQNG--PGLEYKVS 726 Query: 1904 FKTVK-GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 ++ + W + + H ++N +I A N G E + Sbjct: 727 YRRQDVEEDWQEHIV---KRHSFVVKNTPTFVPYEIKIQARNHQGWG--PEPRIATGYSG 781 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSW 1987 PS + + ++ S++V SW Sbjct: 782 EDFPSAAPDDVAVEVINSSVVKVSW 806 Score = 47.2 bits (107), Expect = 0.005 Identities = 29/81 (35%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G V C+V P P ITW + S D + DN TL I EDAG +T Sbjct: 413 EGKRVMMHCKVFSSPSPTITWSKDDT--SDSVDGPRFSVHDN-GTLEIYRAEKEDAGPYT 469 Query: 583 CVAKNAAGFASSTTELIVEAP 603 C AKN G ++ L V+ P Sbjct: 470 CFAKNTEGSSAINAMLSVKDP 490 Score = 46.0 bits (104), Expect = 0.011 Identities = 64/300 (21%), Positives = 117/300 (39%), Gaps = 27/300 (9%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI----LTVE 1192 V W K G + + TI+ + L + + +D G+Y C+ N+ A+ +TVE Sbjct: 249 VEWVKMGQRLP----TKATIESHGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVE 304 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVK 1249 P + PE L +D + + P T VTW + ++D+ V Sbjct: 305 GPP--EWVSEPESQLSMIGSDVLIKCSVSGTPQPT--VTWRVNGNRLQDSPAPN--RRVL 358 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIV-DYEREYRIKRGSDVT 1306 T+++ D Y C + T + + ++ FPP I+ + + +Y G V Sbjct: 359 GDTIVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVM 418 Query: 1307 LLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLENN 1365 + + P P W SK P + +L I + E DAG Y +N Sbjct: 419 MHCKVFSSPSPTITW---SKDDTSDSVDGPRFSVHDNGTLEIYRAEKEDAGPYTCFAKNT 475 Query: 1366 CGHADVEMNVTILDKP---SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI 1422 G + + +++ D PP IL+ ++ + + ++ N I + + +EI Sbjct: 476 EGSSAINAMLSVKDPTRIVEPPEDSRILKGTTAQFSCLAEYDKSFSNDFEILWEKDDKEI 535 Score = 38.3 bits (85), Expect = 2.3 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 5/80 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC G+P PQ+ W + + + + L + V ED G + C Sbjct: 232 GEDLNLECIAAGFPTPQVEWVKMGQRLPTKATI-----ESHGKLLFVPTVEQEDGGKYMC 286 Query: 584 VAKNAAGFASSTTELIVEAP 603 AKN G A + VE P Sbjct: 287 KAKNTLGEAVHYFTVTVEGP 306 Score = 36.7 bits (81), Expect = 7.0 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 3/77 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V +C V G P+P +TW ++ S D T+V+ P D+ + C Sbjct: 321 GSDVLIKCSVSGTPQPTVTWRVNGNRLQDSPAPNRRVLGD---TIVLHNTKPSDSAVYQC 377 Query: 584 VAKNAAGFASSTTELIV 600 A N G S +++ Sbjct: 378 EASNRHGTLLSNANIMI 394 Score = 36.7 bits (81), Expect = 7.0 Identities = 30/132 (22%), Positives = 56/132 (42%), Gaps = 12/132 (9%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCT----AEVTVVELPPEIITRL-QNQKVNKGNKATFEI 1128 + + NT D Y C + T A + ++ PP I+T ++ +G + Sbjct: 362 IVLHNTKPSDSAVYQCEASNRHGTLLSNANIMIMNFPPMILTENDEDYSAVEGKRVMMHC 421 Query: 1129 ELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183 ++ + + W KD + D L+IY + +DAG Y+C G+S Sbjct: 422 KVFSSPSPTITWSKDDTSDSVDGPRFSVHDNGT--LEIYRAEKEDAGPYTCFAKNTEGSS 479 Query: 1184 KCTAILTVEEPS 1195 A+L+V++P+ Sbjct: 480 AINAMLSVKDPT 491 Score = 36.3 bits (80), Expect = 9.2 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 8/113 (7%) Query: 1567 IQQKP-VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 +Q++P ++T + + G++ + + G P P+V W K G +L T + Sbjct: 211 LQRRPSIMTPPGGKSEARLVKGEDLNLECIAAGFPTPQVEWVKMGQRLPT----KATIES 266 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVIM 1675 ++ + +++ KY +A NT G + T+ V P S+PE + M Sbjct: 267 HGKLLFVPTVEQEDGGKYMCKAKNTLGEAVHYFTVTVEGPPEWVSEPESQLSM 319 >UniRef50_UPI0000D55AA5 Cluster: PREDICTED: similar to CG13521-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG13521-PA, isoform A - Tribolium castaneum Length = 1073 Score = 100 bits (240), Expect = 4e-19 Identities = 128/526 (24%), Positives = 204/526 (38%), Gaps = 44/526 (8%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSD--------GDT 786 P++ E +IV + E V L+ + G P PTI W K+ +PVK PT + G Sbjct: 19 PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIA-ETSAVITVEEPTEENAEPPLFINRFQEITVK 845 + + KK +D GVY A N+ G A +A + V +E P + V Sbjct: 79 FFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMP------SDTRVA 132 Query: 846 EKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDY 904 T L R +P P++ W ++ E++ + DG N L+I++V + D G Y Sbjct: 133 AGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVDGGN--LMISDV-RQHDEGRY 189 Query: 905 KCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTKWYHN 963 +CVA N G S V + V F + GK V+ +C V + Sbjct: 190 QCVAHNLVG-SRETPPVMLTVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWRR 248 Query: 964 KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFI 1020 + + I+ + D G+ C ++ T+ +V + P FI Sbjct: 249 EDGKMPIGRARILDD---KSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFI 305 Query: 1021 RKLQDFEVKEKDVAILEVE-INSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRN 1078 K +D +V V + V W ++G +++ N Y L I+ Sbjct: 306 EKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365 Query: 1079 TSVHDEGEYSC----ILRDESCTA--EVT-VVELPPEII-TRLQNQKVNKGNKATFEIEL 1130 D G C + S A +VT V +LPP II NQ + + T + Sbjct: 366 VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425 Query: 1131 TKGDA---LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183 + + +RW KDG +Q + L I D LDD+G Y+C E G S Sbjct: 426 SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 +A L+V E S R P+ P + + + ++ + W Sbjct: 486 SWSASLSVVEGSSALLHRSPDPSTFPKAPNQPRILNATESSITLAW 531 Score = 69.7 bits (163), Expect = 8e-10 Identities = 109/531 (20%), Positives = 202/531 (38%), Gaps = 54/531 (10%) Query: 993 DVGVIKCIVKDQETSTM-----LVVKETIPEFIRKLQDFEVKEKDVAILEVEI--NSETA 1045 D GV C+ ++ S + L V EF D V + A+L+ Sbjct: 91 DAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETALLQCGAPRGHPEP 150 Query: 1046 DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE----VT 1101 +++W +DGE+++ + G+ L I + HDEG Y C+ + + E + Sbjct: 151 NLMWRKDGEVLEVDGRRIRIVDGGN---LMISDVRQHDEGRYQCVAHNLVGSRETPPVML 207 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGK 1159 V + P Q+ G + F+ + G+ + V W ++ ++ +D K Sbjct: 208 TVHVKPFFNKEPQDVVALLGKRVVFQCAVD-GEPVPNVLWRREDGKMPIGR--ARILDDK 264 Query: 1160 KQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAY 1215 L I + D G Y C VG+ A L V P + + + + + Sbjct: 265 S--LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEKPRDQKVSLNGVVEFH 322 Query: 1216 LTVEIPDETLDVTWYKKKS--VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 + + V W K+ S ++ + + TL I+ +D C L Sbjct: 323 CSAT-GNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQGVQREDAGFLVCSALSV 381 Query: 1274 KSTTKLKV-----EVVEFPPKIVDY-EREYRIKRGSDVTLLVDYQA--FPQPNDEWIVNS 1325 ++ ++ V + PP I+ + S VTL + QP W + Sbjct: 382 AGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKASSPEGEQPKIRWSKDG 441 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD------ 1379 K++++ + S++ +L I + D+G+Y + G + ++++++ Sbjct: 442 KVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGESSWSASLSVVEGSSALL 501 Query: 1380 --KPSP------PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEID-TTEWISV 1430 P P P +P IL SSI + WD+ G ++ Y VEY D T W+ Sbjct: 502 HRSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAG---LVGYTVEYWSPDLQTGWVIA 558 Query: 1431 KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQS 1481 + ++ LK +SSY F A N +S AS + + + ++ S Sbjct: 559 AHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSSIARTLANSRAVS 609 Score = 64.1 bits (149), Expect = 4e-08 Identities = 91/397 (22%), Positives = 150/397 (37%), Gaps = 53/397 (13%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPS----QDFQMYYDDDNVATL-VIREVFPEDAGTF 581 V C+ EG P P I WF+ +K S + ++ ++ L + +DAG + Sbjct: 36 VTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSLFFLRTMNSKKEQDAGVY 95 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 CVA+N AG A S + A L D E V A +L+ P +P Sbjct: 96 WCVARNTAGSAVSRNATLQVAVLRD---EFRVMPSDTRVAAGETA-LLQCGAPRGHPEPN 151 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 + +G + ++ R + IV N+ + SD+ + + Sbjct: 152 LMWRKDGEVLEVDGRRI--------------RIVDGGNLMI---SDVRQH-------DEG 187 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 ++Q + +V L + +K KEP V+ L G+ V+ V G Sbjct: 188 RYQCVAHNLVGSRETPPVMLTVHVK-PFFNKEPQDVVALL-------GKRVVFQCAVDGE 239 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P P + W + + + + D ++ + DEG+Y AEN G A + Sbjct: 240 PVPNVLWRREDGKMPIGRARILDD--KSLLIDNVQTSDEGIYICAAENVVGSITAKASLV 297 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--IISPSETI 879 V PP FI + ++ V G ++ T NP PS+ W + ++ P + Sbjct: 298 VN-------SPPTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSY 350 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 + L I V E D+G C A + AG SS Sbjct: 351 GHMHVNAHGTLRIQGVQRE-DAGFLVCSALSVAGSSS 386 Score = 63.3 bits (147), Expect = 7e-08 Identities = 161/824 (19%), Positives = 291/824 (35%), Gaps = 78/824 (9%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKSASL 1345 P+I ++ + + + VTL + P+P EW + + +K S + + SL Sbjct: 19 PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78 Query: 1346 ----TIKKVENTDAGIYKLRLENNCGHA---DVEMNVTIL-DKPSPPGKPNILEIDSSSI 1397 T+ + DAG+Y N G A + + V +L D+ + +++ Sbjct: 79 FFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAGETAL 138 Query: 1398 NICWDEPENTGNSTIIYYVV-EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 C P +++ E E+D ++ + I +++ + R++ A Sbjct: 139 LQC-GAPRGHPEPNLMWRKDGEVLEVDGRR---IRIVDGGNLMISDVRQHDEGRYQCVAH 194 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 N V S T + K P K +++ + + C G P P V W Sbjct: 195 NLV----GSRETPPVMLTVHVK---PFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWR 247 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITIS 1576 R+ K+ +A + Y C A N G + + + P Sbjct: 248 REDGKMPIGRARILDDKSLLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEK 307 Query: 1577 NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK--LENDKEYNITTKEKTSVIRIKE 1634 D K E+ +A G PPP V W K G++ + D Y +RI+ Sbjct: 308 PRDQKVSLNGVVEFHCSAT--GNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-----GPVIMREISRESVTIEWKP 1689 ++R + A + AG+SSV L+V P GP VT+ K Sbjct: 366 VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425 Query: 1690 PLDDGGLELTKYA------IEKHEPDNNRWIKVADVD------RDVETYCIQKLNENCEY 1737 +G +++ E+ PD + +D D Y ++E+ E Sbjct: 426 SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 + G S L P T P+ S+ + W + G Sbjct: 486 SWSASLSVVEGSSALLHRSPDP-STFPKAPNQPRILNAT----ESSITLAWDDGPEAG-- 538 Query: 1798 PIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS--LPYTS 1853 ++ Y VE + W +++L +++Y F + A N G S P +S Sbjct: 539 -LVGYTVEYWSPDLQTGWVIAAHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSS 597 Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPIT------NYI----IE 1903 + T+ + + + +++ V L+ P+S+ +T +YI I Sbjct: 598 IAR-TLANSRAVSGSELDTARTALSTKLVELRDARPQSSSSVKLTWSLAALDYIEGLYIR 656 Query: 1904 FKTVKGKSWT-KIVTV-GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 F+ + G S I+TV + + N+K+ + F I+ P+ S+ + + Sbjct: 657 FRELSGGSHNYNILTVLDVQTKSYTVSNLKKFTKYEFFIAPFYKSVEGQPSNSRVAQTLE 716 Query: 1962 HATVPSPPTAPLEIRMVGSNIVMTSWG-TPEWDGGAPLLGYNIAIR-DVTKTMWMEVGKV 2019 VPS P + + W P ++GY I IR +T+++ V Sbjct: 717 --DVPSAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRGSITRSL-----TV 769 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + +T I +L+ +Y RI A G P + P P Sbjct: 770 NSSTTSVLISNLTSGGSYNARIAALTHAG-QGPYSNQVPLLTAP 812 Score = 62.5 bits (145), Expect = 1e-07 Identities = 64/298 (21%), Positives = 115/298 (38%), Gaps = 21/298 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P F+K+P+ G ++ +C + P P++ W + + +P + + Sbjct: 211 VKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLWR-REDGKMPIGRARILDDKS---- 265 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L I NV+ EG Y A N G + L + + PP IE + V Sbjct: 266 ---LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNS----PPTFIEKPRDQKVSLNGV 318 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDG----DTHSITILKPKKVKDEGVYTLKA 807 V GNP P++ W K + P S G + H ++ + +D G A Sbjct: 319 VEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQGVQREDAGFLVCSA 378 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFI--NRFQEITVKEKGTIKLVARVTRNPVPSIT 865 + G + A + V + PP+ Q + + T+ A P I Sbjct: 379 LSVAGSSSVRAFLQVTSVAD--LPPPIIQIGPANQTLPLHSMVTLHCKASSPEGEQPKIR 436 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W ++ +++ + E L I ++ + DSG Y C A + +G+SS A +++ Sbjct: 437 WSKDGKVLQEERLPDRYTISETGTLDIDDLRLD-DSGLYTCSAISESGESSWSASLSV 493 Score = 60.9 bits (141), Expect = 4e-07 Identities = 77/307 (25%), Positives = 124/307 (40%), Gaps = 27/307 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI--VPDENIS--VAIESDMH 689 P ++ P V + + L C+ PEP I W GE + P +N S V + + Sbjct: 19 PRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKTSPTDNKSHRVLLPAGSL 78 Query: 690 MYCSVLKITNVKKFQE-GTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + L+ N KK Q+ G Y VA N G A S L++ E + + V Sbjct: 79 FF---LRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTR---VA 132 Query: 748 QGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 GE+ +L G+P P + W K+ + ++ + ++ + DEG Y Sbjct: 133 AGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVDGGNLMISDVRQHDEGRYQCV 192 Query: 807 AENSEGIAETSAV-ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A N G ET V +TV N EP Q++ + V PVP++ Sbjct: 193 AHNLVGSRETPPVMLTVHVKPFFNKEP-------QDVVALLGKRVVFQCAVDGEPVPNVL 245 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W R + + + D ++ L+I NV + D G Y C A N G + A + ++ Sbjct: 246 WRREDGKMPIGR--ARILDDKS--LLIDNVQTS-DEGIYICAAENVVGSITAKASLVVN- 299 Query: 926 EKVTFVK 932 TF++ Sbjct: 300 SPPTFIE 306 Score = 57.6 bits (133), Expect = 4e-06 Identities = 48/207 (23%), Positives = 91/207 (43%), Gaps = 13/207 (6%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV--PDENISVA 683 A ++ PPTF +KP+ Q V + C P P + W +G +++ PD + Sbjct: 294 ASLVVNSPPTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSY--- 350 Query: 684 IESDMHMYC-SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--P 740 MH+ L+I V++ G A++ G +S+ L++ + PP +I+ P Sbjct: 351 --GHMHVNAHGTLRIQGVQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGP 408 Query: 741 L-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKV 797 +++ + ++ A +P I W K+ K + + LP + + ++ Sbjct: 409 ANQTLPLHSMVTLHCKASSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRL 468 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEE 824 D G+YT A + G + SA ++V E Sbjct: 469 DDSGLYTCSAISESGESSWSASLSVVE 495 Score = 50.0 bits (114), Expect = 7e-04 Identities = 162/807 (20%), Positives = 288/807 (35%), Gaps = 78/807 (9%) Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFS-----NHIQLTI 1156 + E P +II +N+ V KA E T + WFKDG ++ S +H L Sbjct: 21 ITEHPSDIIVA-KNEPVTLNCKAEGRPEPT-----IEWFKDGEPVKTSPTDNKSHRVLLP 74 Query: 1157 DGKKQKLKIYDCDLD-DAGEYSCEVGNSKCTAI---LTVEEPSINFTLR-LPEFILVPAN 1211 G L+ + + DAG Y C N+ +A+ T++ + R +P V A Sbjct: 75 AGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDEFRVMPSDTRVAAG 134 Query: 1212 TDAYLTVEIP--DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 A L P ++ W K V+E + I D L+I + D+ Y CV Sbjct: 135 ETALLQCGAPRGHPEPNLMWRKDGEVLEVDGRRIRIVD--GGNLMISDVRQHDEGRYQCV 192 Query: 1270 ---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 L+ ++ T + + V P ++ G V P PN W + Sbjct: 193 AHNLVGSRETPPVML-TVHVKPFFNKEPQDVVALLGKRVVFQCAVDGEPVPNVLW--RRE 249 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGK 1386 K +D KS L I V+ +D GIY EN G + ++ + P+ K Sbjct: 250 DGKMPIGRARILDDKS--LLIDNVQTSDEGIYICAAENVVGSITAKASLVVNSPPTFIEK 307 Query: 1387 PNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKT 1445 P ++ S + TGN +++ E ++ S ++ ++ Sbjct: 308 PRDQKV--SLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAHGTLRIQG 365 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIF 1505 + + ++ +S + +V + P ++ N T + + L C Sbjct: 366 VQREDAGFLVCSALSVAGSSSVRAFLQVTSVADLPPPIIQIGPANQTLPLHSMVTLHCKA 425 Query: 1506 GGV--PQPKVTWYRDGKKLKTAKA----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGE- 1558 QPK+ W +DGK L+ + T Y C A ++ GE Sbjct: 426 SSPEGEQPKIRWSKDGKVLQEERLPDRYTISETGTLDIDDLRLDDSGLYTCSAISESGES 485 Query: 1559 --------VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK-N 1609 VE S + + T + + E +T + P ++ Y Sbjct: 486 SWSASLSVVEGSSALLHRSPDPSTFPKAPNQPRILNATESSITLAWDDGPEAGLVGYTVE 545 Query: 1610 GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG------TSSVEVTLKVY 1663 + + I ++ I ++ELK S + + A N G SS+ TL Sbjct: 546 YWSPDLQTGWVIAAHRVSNYIVVRELKPDSSYMFIVRAENAHGLSPASPVSSIARTLANS 605 Query: 1664 DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD--- 1720 S E +S + V + P ++LT +++ + +I+ ++ Sbjct: 606 RAVSGSELDTARTALSTKLVELRDARPQSSSSVKLT-WSLAALDYIEGLYIRFRELSGGS 664 Query: 1721 --------RDVET--YCIQKLNENCEYMFRVIAQNPVGFSEALESEPI---VIKTALDVP 1767 DV+T Y + L + +Y F + F +++E +P V +T DVP Sbjct: 665 HNYNILTVLDVQTKSYTVSNLKKFTKYEFFI-----APFYKSVEGQPSNSRVAQTLEDVP 719 Query: 1768 SXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI 1826 S ++ + ++ W P ++ II YK++I+ + I Sbjct: 720 SAPPDGVTAGVFNDTAGWVRWSPPPPQHHNGIIIGYKIQIRGSITR-SLTVNSSTTSVLI 778 Query: 1827 QKLSINTTYQFRIYARNEIGTSLPYTS 1853 L+ +Y RI A G PY++ Sbjct: 779 SNLTSGGSYNARIAALTHAGQG-PYSN 804 Score = 46.8 bits (106), Expect = 0.007 Identities = 45/216 (20%), Positives = 90/216 (41%), Gaps = 18/216 (8%) Query: 1465 SETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 +E + + + +++ +SP + + +I NE + L C G P+P + W++DG+ +KT Sbjct: 2 AECEKSWAQLNDSQFRSPRITEHPSDIIVAKNEPVTLNCKAEGRPEPTIEWFKDGEPVKT 61 Query: 1525 AKATYENR----------XXXXXXXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQ-QKPV 1572 + ++ Y C+A N G V + + + + Sbjct: 62 SPTDNKSHRVLLPAGSLFFLRTMNSKKEQDAGVYWCVARNTAGSAVSRNATLQVAVLRDE 121 Query: 1573 ITISNEDIKQKHKVGDEWLV-TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 + D + G+ L+ G P P ++W K+G LE D I + +++ Sbjct: 122 FRVMPSDTRV--AAGETALLQCGAPRGHPEPNLMWRKDGEVLEVDGR-RIRIVDGGNLM- 177 Query: 1632 IKELKRSHSSKYTIEASNTAGT-SSVEVTLKVYDKP 1666 I ++++ +Y A N G+ + V L V+ KP Sbjct: 178 ISDVRQHDEGRYQCVAHNLVGSRETPPVMLTVHVKP 213 Score = 44.4 bits (100), Expect = 0.035 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 3/86 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVAT 567 P F+EK R + V+F C G P P + W ++ + ++ P + + + + T Sbjct: 302 PTFIEKPRDQKVSLNGVVEFHCSATGNPPPSVFWTKEGSQMLMFPDNSYGHMHVNAH-GT 360 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFAS 593 L I+ V EDAG C A + AG +S Sbjct: 361 LRIQGVQREDAGFLVCSALSVAGSSS 386 Score = 43.2 bits (97), Expect = 0.081 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V F+C V+G P P + W R+ + + DD + L+I V D G + C Sbjct: 227 GKRVVFQCAVDGEPVPNVLWRREDGKMPIGR--ARILDDKS---LLIDNVQTSDEGIYIC 281 Query: 584 VAKNAAGFASSTTELIVEAP 603 A+N G ++ L+V +P Sbjct: 282 AAENVVGSITAKASLVVNSP 301 >UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-Mlck CG18255-PA, isoform A; n=2; Coelomata|Rep: PREDICTED: similar to Stretchin-Mlck CG18255-PA, isoform A - Apis mellifera Length = 3978 Score = 100 bits (239), Expect = 5e-19 Identities = 104/443 (23%), Positives = 181/443 (40%), Gaps = 46/443 (10%) Query: 496 PVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD 555 P+ +K E+ P F +L + G + C V G+P P++ W + + + + Sbjct: 3445 PIKDKLAPREKGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTN 3504 Query: 556 FQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXX 615 D+ +A + E PED+G +TCVA+N G AS+ + L V S T Sbjct: 3505 KYKTRFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTR 3564 Query: 616 XXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV 675 + G + + Y ++++LECR+ P P I+WL G + Sbjct: 3565 S------------IRG----YIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILR 3608 Query: 676 PDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN--REGEASLPIVLK------I 727 D ++ ++ L+I K G YT A+N R E S + + Sbjct: 3609 GDRYKQSYLDDGIYR----LEIAAPKSTDNGRYTCRAMNDLRTEEISHIVQFNERDRRIV 3664 Query: 728 KTGEK-----------EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK--P 774 EK + P+ L V G ++ L +V G P P + W + + P Sbjct: 3665 NKHEKLFDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREP 3724 Query: 775 VKALPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAVITVEEPTE-ENAEP 832 V K+ ++ T++ P+ + E G Y +A N+ G ++ A + V P+ + +P Sbjct: 3725 VSIPKAKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKP 3784 Query: 833 PLFINRFQE--ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 +F++R E ITV + + RVT P P +TW + + I+ + + + L Sbjct: 3785 AMFVSRPSEKSITVNSGEDVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDYVRL 3844 Query: 891 VITNVDSEIDSGDYKCVASNSAG 913 + V + D G Y + N G Sbjct: 3845 TLKRVVA-TDEGTYCILVKNRYG 3866 Score = 84.2 bits (199), Expect = 4e-14 Identities = 81/305 (26%), Positives = 122/305 (40%), Gaps = 23/305 (7%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 EC+V G P P I+W + I++ + ++ Y DD + L I D G +TC A N Sbjct: 3587 ECRVRGNPTPVISWLKDGCILRGDR-YKQSYLDDGIYRLEIAAPKSTDNGRYTCRAMN-- 3643 Query: 590 GFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS 649 TE I + V + + P FS V G Sbjct: 3644 ---DLRTEEISHIVQFNERDRRIVNKHEKLFDDYFSLETYKR--PRFSSYLSDYSVPTGG 3698 Query: 650 DILLECRLVAIPEPDIAWLFKGE--EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 I L+ + +P P++ W F+GE E V ES +H L + V + ++GT Sbjct: 3699 TIALQVEVKGVPAPEVRW-FRGERREPVSIPKAKTFTESGVH----TLVLPEVTESEKGT 3753 Query: 708 YTVVAVNREGEASLPIVLKIKT-----GEKEPPQVIEPL-KSMIVRQGESVILSAQVVGN 761 Y A+N G +++ + G K V P KS+ V GE V +S +V G Sbjct: 3754 YICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVSRPSEKSITVNSGEDVSVSFRVTGI 3813 Query: 762 PRPTITWCKNNKPVK--ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 P+P +TW K K + K D + LK DEG Y + +N G + Sbjct: 3814 PKPRVTWMKGLKDITDGLRSHKETIDDYVRLTLKRVVATDEGTYCILVKNRYGCDRSFFS 3873 Query: 820 ITVEE 824 I V++ Sbjct: 3874 IKVKQ 3878 Score = 72.5 bits (170), Expect = 1e-10 Identities = 77/324 (23%), Positives = 123/324 (37%), Gaps = 35/324 (10%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIESDM 688 +G P+F + + V G L C ++ PEP + W GE++ + ++ M Sbjct: 3455 KGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKTRFDNGM 3514 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK---EPPQVIEPLKSMI 745 + ++ G YT VA N G AS LK+ + PP ++ I Sbjct: 3515 AYF----ELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTRSIRGYI 3570 Query: 746 ------VRQGES-VILSAQVVGNPRPTITWCKNNKPVKALPTKS---DGDTHSITILKPK 795 R ++ +IL +V GNP P I+W K+ ++ K D + + I PK Sbjct: 3571 RFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRGDRYKQSYLDDGIYRLEIAAPK 3630 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTE----------------ENAEPPLFINRF 839 D G YT +A N E S ++ E E + P F + Sbjct: 3631 ST-DNGRYTCRAMNDLRTEEISHIVQFNERDRRIVNKHEKLFDDYFSLETYKRPRFSSYL 3689 Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 + +V GTI L V P P + W+R S + F + ++ +E Sbjct: 3690 SDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLVLPEVTES 3749 Query: 900 DSGDYKCVASNSAGKSSHGARVTI 923 + G Y C A N+ G A V + Sbjct: 3750 EKGTYICRAINAYGHVDSIATVEV 3773 Score = 69.7 bits (163), Expect = 8e-10 Identities = 64/234 (27%), Positives = 99/234 (42%), Gaps = 30/234 (12%) Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 +++ K +KL F+ S E P F L P G T+ + +V+G P P++ WFR Sbjct: 3661 RRIVNKHEKL--FDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFR 3718 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS 605 S + + V TLV+ EV + GT+ C A NA G S + V +P + Sbjct: 3719 GERREPVSIPKAKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSA 3778 Query: 606 DHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP--KAQYVDEGSDILLECRLVAIPEP 663 G G P F +P K+ V+ G D+ + R+ IP+P Sbjct: 3779 IDG----------------------GKPAMFVSRPSEKSITVNSGEDVSVSFRVTGIPKP 3816 Query: 664 DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 + W+ KG + + D S D ++ L + V EGTY ++ NR G Sbjct: 3817 RVTWM-KGLKDITDGLRSHKETIDDYVR---LTLKRVVATDEGTYCILVKNRYG 3866 Score = 50.4 bits (115), Expect = 5e-04 Identities = 47/202 (23%), Positives = 72/202 (35%), Gaps = 17/202 (8%) Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 K+ K + P+ L N T LTC G P+P+V W +DG+KL Y+ Sbjct: 3449 KLAPREKGKKPSFCTRLTNRTVGVGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKT 3508 Query: 1532 RXXXXXXXXXX-----XXXXXYKCIAFNDHGEVETSCVVGIQ-------QKPVITISNED 1579 R Y C+A N HG T + + P T S Sbjct: 3509 RFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKVYPDFQPTLSPPTFTRSIRG 3568 Query: 1580 ----IKQKHKVGD-EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 ++ D E ++ + G P P + W K+G L D+ + + I Sbjct: 3569 YIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRGDRYKQSYLDDGIYRLEIAA 3628 Query: 1635 LKRSHSSKYTIEASNTAGTSSV 1656 K + + +YT A N T + Sbjct: 3629 PKSTDNGRYTCRAMNDLRTEEI 3650 Score = 44.0 bits (99), Expect = 0.046 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 1/79 (1%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 VG + +T + G P P V W K+G KL+ +Y + + E S YT Sbjct: 3472 VGMKTRLTCTVLGHPEPRVYWTKDGEKLDITTNKYKTRFDNGMAYFELHEPLPEDSGLYT 3531 Query: 1645 IEASNTAGTSSVEVTLKVY 1663 A N G +S E LKVY Sbjct: 3532 CVAENVHGIASTESALKVY 3550 Score = 41.9 bits (94), Expect = 0.19 Identities = 80/378 (21%), Positives = 135/378 (35%), Gaps = 58/378 (15%) Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD----ESCTAEVTV 1102 V W +DGE + NKY + + D G Y+C+ + S + + V Sbjct: 3490 VYWTKDGEKLDITTNKYKTRFDNGMAYFELHEPLPEDSGLYTCVAENVHGIASTESALKV 3549 Query: 1103 VE-----LPPEIITRLQNQKV--------NKGNKATFEIELTKGDA-LVRWFKDGSEIQF 1148 L P TR + + N+ E + ++ W KDG ++ Sbjct: 3550 YPDFQPTLSPPTFTRSIRGYIRFCNYTYRSSDNELILECRVRGNPTPVISWLKDGCILRG 3609 Query: 1149 SNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA--------------ILTVEEP 1194 + Q +D +L+I D G Y+C N T I+ E Sbjct: 3610 DRYKQSYLDDGIYRLEIAAPKSTDNGRYTCRAMNDLRTEEISHIVQFNERDRRIVNKHEK 3669 Query: 1195 SIN--FTL---RLPEF------ILVPANTDAYLTVEIPDETL-DVTWYK-KKSVIEDTEK 1241 + F+L + P F VP L VE+ +V W++ ++ K Sbjct: 3670 LFDDYFSLETYKRPRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPK 3729 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVD--------- 1292 ++ TL++ + TE ++ Y C ++A V P +D Sbjct: 3730 AKTFTESGVHTLVLPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVS 3789 Query: 1293 --YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK-IIKKCKHTKPSIDSKSASLTIKK 1349 E+ + G DV++ P+P W+ K I + K +ID LT+K+ Sbjct: 3790 RPSEKSITVNSGEDVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDY-VRLTLKR 3848 Query: 1350 VENTDAGIYKLRLENNCG 1367 V TD G Y + ++N G Sbjct: 3849 VVATDEGTYCILVKNRYG 3866 Score = 39.5 bits (88), Expect = 0.99 Identities = 42/194 (21%), Positives = 70/194 (36%), Gaps = 13/194 (6%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKK----LKTAKATYENRXXXXX 1537 P L + + I L GVP P+V W+R ++ + AK E+ Sbjct: 3683 PRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLV 3742 Query: 1538 X-XXXXXXXXXYKCIAFNDHGEVETSCVVGIQQ-------KPVITISNEDIKQ-KHKVGD 1588 Y C A N +G V++ V + KP + +S K G+ Sbjct: 3743 LPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKPAMFVSRPSEKSITVNSGE 3802 Query: 1589 EWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 + V+ + GIP P V W K + + + T + + +K + + Y I Sbjct: 3803 DVSVSFRVTGIPKPRVTWMKGLKDITDGLRSHKETIDDYVRLTLKRVVATDEGTYCILVK 3862 Query: 1649 NTAGTSSVEVTLKV 1662 N G ++KV Sbjct: 3863 NRYGCDRSFFSIKV 3876 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/102 (23%), Positives = 40/102 (39%), Gaps = 2/102 (1%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK-KCKHTKPSIDSKSASLT 1346 P+ Y +Y + G + L V+ + P P W + K +S +L Sbjct: 3683 PRFSSYLSDYSVPTGGTIALQVEVKGVPAPEVRWFRGERREPVSIPKAKTFTESGVHTLV 3742 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKP 1387 + +V ++ G Y R N GH D V ++ + GKP Sbjct: 3743 LPEVTESEKGTYICRAINAYGHVDSIATVEVISPSAIDGGKP 3784 >UniRef50_Q0E8G9 Cluster: CG33274-PB; n=9; Endopterygota|Rep: CG33274-PB - Drosophila melanogaster (Fruit fly) Length = 1876 Score = 100 bits (239), Expect = 5e-19 Identities = 173/848 (20%), Positives = 320/848 (37%), Gaps = 81/848 (9%) Query: 707 TYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV------ 759 +YT VNR GE + + EP +++P ++ V+L+ Q Sbjct: 64 SYTCRTVNRLTGEVQIS-TYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTTLPCIAQ 122 Query: 760 GNPRPTITWCKN-NKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKAENSEGIAET 816 G+P PT W K N+ + L S +LK K + D G Y N+ G Sbjct: 123 GHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEETI 182 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 +TV P + +P + Q + V + + + V+ +PV + W + + I Sbjct: 183 QVSLTVTAPLTAHLQPQV-----QTVDVDKDAQFQCI--VSGHPVHDVNWLHDGKPILRD 235 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + D L+I V E D G Y+C SN + A + + + + Sbjct: 236 NRVEILTDPPR--LIIKKVQKE-DPGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSE 292 Query: 937 SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREI-------IQEGRXXXXXXXXX 989 + G TV L+C + ++ + D I + Sbjct: 293 Q-TLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNV 351 Query: 990 XXXDVGVIKCIVKDQETSTMLVVKETIP--EFIRKLQDFEVKEKDVAILEVEINSETADV 1047 D G C ++ K I +IR++ I++ + D Sbjct: 352 KEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDK 411 Query: 1048 V-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVEL- 1105 + WERDG+ + + + + I + R + D G Y+C+ +++ VE+ Sbjct: 412 IHWERDGQTLPINRRQRAYNNGTLIIEQLQR---LEDAGTYTCMAQNKQKQTSRRNVEIQ 468 Query: 1106 ---PPEIIT-RLQNQKVNKGNKATFEIELTKGDALV--RWFKDGSE-IQFSNHIQLTIDG 1158 PP+I+ + + +G +A ++ +GD V RW ++G I N + +D Sbjct: 469 VLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDE 528 Query: 1159 KKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTV 1218 L I D +G Y+C N T TV ++N P++IL P ++ A Sbjct: 529 YSASLVIEHISSDHSGNYTCIASNVAGTERFTVPL-TVNVP---PKWILEPKDSSAQAGA 584 Query: 1219 EI-------PDETLDVTWYKKKSVIEDTEKFTLISDVKKR----TLIIRKCTEDDQCEYT 1267 ++ T +TW K K L + T+ +K +++ Q + Sbjct: 585 DVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFL 644 Query: 1268 CVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNS 1325 C + +K+ V P ++ + +G V + + Q + +W + + Sbjct: 645 CEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQA 704 Query: 1326 --KIIKKCKHTKPSI------DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + + + ++ +I D + L I D GIY + N G ++ + + + Sbjct: 705 TQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIV 764 Query: 1378 LDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT--- 1434 + P P I S S+ + W +P GNS I Y + Y++I W + +++T Sbjct: 765 QEVPEQPKNLRINSQQSRSLQLTWSQP-FAGNSPIEEYHIYYKQISDI-WQNAEHLTIAG 822 Query: 1435 -KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 +T +IQ L+ +Y R A N++ S+ SE V++ T ++ PL + Sbjct: 823 AQTVINIQQLRPAKAYHIRMSAENKLGASEFSE------VVQVTTLEEVPSGPPLA-VRA 875 Query: 1494 EPNEDIEL 1501 EP E+ Sbjct: 876 EPKSSTEI 883 Score = 88.2 bits (209), Expect = 2e-15 Identities = 185/908 (20%), Positives = 346/908 (38%), Gaps = 79/908 (8%) Query: 638 KKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 +K ++V L C P P W + E + +S I + +LKI Sbjct: 102 EKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFKEENEQLLPLQLSERITI---VSAGLLKI 158 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 T + G Y N GE ++ + L + ++P + V + Sbjct: 159 TKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAH---LQP-QVQTVDVDKDAQFQCI 214 Query: 758 VVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAET 816 V G+P + W + KP+ + + D + I K +K +D G+Y N ++ Sbjct: 215 VSGHPVHDVNWLHDGKPILRDNRVEILTDPPRLIIKKVQK-EDPGMYQCFVSNEWEQIQS 273 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 +A + + + A P L + F E T++ T+ L T NP+P TW + I S Sbjct: 274 TAELQLGD-----ASPEL-LYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDS 327 Query: 877 ETITQN-----FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFV 931 D + I+NV E D G+Y C A N+ GK SH A+V ++ + ++ Sbjct: 328 SRFLVGQYVTIHDDVISHVNISNVKEE-DGGEYTCTAQNAIGKVSHSAKV--NIYGLPYI 384 Query: 932 KHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 + + K G +I++C + K + + + +R Sbjct: 385 REMPK-ITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQRL 443 Query: 992 XDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDFE--VKEKDVAILEVEINSETAD 1046 D G C+ ++++ T + ++ +P I +Q ++E A + +I Sbjct: 444 EDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLP 503 Query: 1047 VV--WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV-- 1102 V WER+G+ + N+ + L I + S G Y+CI + + T TV Sbjct: 504 VSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPL 563 Query: 1103 -VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK-------DGSEIQFSNHIQ 1153 V +PP+ I ++ G + + + W K + + + +Q Sbjct: 564 TVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQ 623 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL---PEFILVPA 1210 L +G KI + G + CE N+ + + V +N + I V Sbjct: 624 LFPNGTIFFKKI---SKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAK 680 Query: 1211 NTDAYLTVEIP-DETLDVTW--YKKKSVIEDT--EKFTL----ISDVKKRTLIIRKCTED 1261 ++ + D +D W + ++++ ++T+ + D L I Sbjct: 681 GKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQ 740 Query: 1262 DQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY-QAFP--QPN 1318 D Y C +A ++ ++++ ++ + + RI +L + + Q F P Sbjct: 741 DTGIYICQASNAFGQDEMSIQLI--VQEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPI 798 Query: 1319 DEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL--ENNCGHADVE--MN 1374 +E+ + K I + A I + A Y +R+ EN G ++ + Sbjct: 799 EEYHIYYKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQ 858 Query: 1375 VTILDK-PS-PPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVK 1431 VT L++ PS PP S+ I + WD PE + N ++ Y V YQ T E K Sbjct: 859 VTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPE---DK 915 Query: 1432 NITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNI 1491 + TQ + KT R++ E +++ ++ T+Y+ +++ Q P K I Sbjct: 916 EVNPTQGF--SFKT---VEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGS--GPPSKEI 968 Query: 1492 TTEPNEDI 1499 + ED+ Sbjct: 969 AVQTMEDV 976 Score = 87.8 bits (208), Expect = 3e-15 Identities = 206/986 (20%), Positives = 365/986 (37%), Gaps = 89/986 (9%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130 L I + D G+Y C + + + + V V P + Q Q V+ A F+ + Sbjct: 156 LKITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQC-I 214 Query: 1131 TKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS----K 1184 G + V W DG I N +++ D +L I +D G Y C V N + Sbjct: 215 VSGHPVHDVNWLHDGKPILRDNRVEILTD--PPRLIIKKVQKEDPGMYQCFVSNEWEQIQ 272 Query: 1185 CTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244 TA L + + S E L P T + V + TW I D+ +F + Sbjct: 273 STAELQLGDASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLV 332 Query: 1245 -----ISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREY 1297 I D + I E+D EYTC +A K + KV + P I + + Sbjct: 333 GQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLP-YIREMPKIT 391 Query: 1298 RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT-DAG 1356 I GSD+ + +P W + + + + + + +L I++++ DAG Sbjct: 392 GIS-GSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAY---NNGTLIIEQLQRLEDAG 447 Query: 1357 IYKLRLENN---CGHADVEMNVTILDKPSP-PGKPNILEIDSSSINICWDEPENTGNSTI 1412 Y +N +VE+ V + K P N+L + C G+ + Sbjct: 448 TYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISC---QILEGDLPV 504 Query: 1413 IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 + E + I N + + + ++ N I+ TE + Sbjct: 505 SFR----WERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFT 560 Query: 1473 VIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR 1532 V + + +P K+ + + D+ L C G P P +TW K + Y++ Sbjct: 561 VPLTVNVPPKWILEP-KDSSAQAGADVLLHCQSSGYPTPTITWK---KAIGPTPGEYKDF 616 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHG----EVETSCVVGIQQKPVITIS---NEDIKQKH- 1584 +K I+ G E + + G+ + + ++ + K K Sbjct: 617 LYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQI 676 Query: 1585 --KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVI---RIKELKRSH 1639 G + V ++G P + W + D+ + + V+ + EL SH Sbjct: 677 SVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISH 736 Query: 1640 SSK-----YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDG 1694 + + Y +ASN G + + L V + P +P+ I + SR S+ + W P G Sbjct: 737 TYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSR-SLQLTWSQPFA-G 794 Query: 1695 GLELTKYAIEKHEPDNNRWIKVADVD-RDVETYC-IQKLNENCEYMFRVIAQNPVGFSEA 1752 + +Y I ++ ++ W + +T IQ+L Y R+ A+N +G SE Sbjct: 795 NSPIEEYHIY-YKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEF 853 Query: 1753 LESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI-----IDYKVEIK 1807 SE + + T +VPS + +++TW E++ + I + Y++ + Sbjct: 854 --SEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLT 911 Query: 1808 QEGKKWKXXXXXXXXXARIQ----------KLSINTTYQFRIYARNEIGTSLPYTSDDKI 1857 E K+ ++ L+ T Y + A G+ P Sbjct: 912 PEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGSGPPSKEIAVQ 971 Query: 1858 TIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNG-GSPITNYIIEFKTVKGKSWTKI 1915 T+ +PP P+ V+ S S+ + W+ P+ +G I Y + + +V T Sbjct: 972 TMEDVPSSPPESPQCDVLG---STSIYITWSPPDIDGQNGKIKGYKVFYISVDELYETDP 1028 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 V + IEN+++ + A VG + T+ R H VPS P A I Sbjct: 1029 EVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCR--THEDVPSAPQAIKAI 1086 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGY 2001 S I++ SW P+ G + GY Sbjct: 1087 PASSSKIII-SWLPPDLPNG-DITGY 1110 Score = 80.2 bits (189), Expect = 6e-13 Identities = 123/586 (20%), Positives = 222/586 (37%), Gaps = 59/586 (10%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P T +P+ Q VD D +C + P D+ WL G+ I+ D + + + Sbjct: 191 PLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPR---- 246 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I V+K G Y V+ E E + +++ G+ P+++ ++ G +V Sbjct: 247 --LIIKKVQKEDPGMYQCF-VSNEWE-QIQSTAELQLGDAS-PELLYWFSEQTLQPGPTV 301 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDG-------DTHSITILKPKKVKDEGVYTL 805 L GNP P TW + P+ G D S + K +D G YT Sbjct: 302 SLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTC 361 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A+N+ G SA + + P +I +IT + + V P+ I Sbjct: 362 TAQNAIGKVSHSAKVNI------YGLP--YIREMPKITGISGSDLIVKCPVAGYPIDKIH 413 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W R+ + + P + ++ N L+I + D+G Y C+A N ++S V I V Sbjct: 414 WERDGQTL-PINRRQRAYN--NGTLIIEQLQRLEDAGTYTCMAQNKQKQTSR-RNVEIQV 469 Query: 926 EKVTFVKHLQ-KSYETEEGKTVILECQTSH---TVSTKWYHNKKEISGMDHREIIQEGRX 981 + +Q + EG + CQ VS +W N K + G + + Sbjct: 470 LVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEY 529 Query: 982 XXXXXXXXXXXD-VGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAILE 1037 D G CI + + V T+ P++I + +D + +L Sbjct: 530 SASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLH 589 Query: 1038 VEINS-ETADVVWERDGEIIKPKKNKY-DFEKRGHIR-----KLYIRNTSVHDEGEYSCI 1090 + + T + W++ I P +Y DF ++ ++ + S +G + C Sbjct: 590 CQSSGYPTPTITWKK---AIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCE 646 Query: 1091 LRDE--SCTAEVTV--VELPPEIITRLQNQKVNKGNKATFEIELT---------KGDALV 1137 ++ S ++V V +P T+ + V KG + + + K A Sbjct: 647 AKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQ 706 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 ++ + + +++ Q+ DG +L I D G Y C+ N+ Sbjct: 707 QYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNA 752 Score = 78.6 bits (185), Expect = 2e-12 Identities = 190/962 (19%), Positives = 353/962 (36%), Gaps = 82/962 (8%) Query: 1138 RWFKDGSE----IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE- 1192 RWFK+ +E +Q S I + G LKI L+D+G+Y C V N+ + V Sbjct: 130 RWFKEENEQLLPLQLSERITIVSAGL---LKITKARLEDSGKYLCWVNNTAGEETIQVSL 186 Query: 1193 EPSINFTLRL-PEFILVPANTDAYLTVEIPDETL-DVTW-YKKKSVIEDTEKFTLISDVK 1249 + T L P+ V + DA + + DV W + K ++ D + +++D Sbjct: 187 TVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDN-RVEILTDPP 245 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 + LII+K ++D Y C + + + + ++++ + P+++ + E ++ G V+L Sbjct: 246 R--LIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTVSL 303 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI-----DSKSASLTIKKVENTDAGIYKLRL 1362 P P W ++ I D + + I V+ D G Y Sbjct: 304 KCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTA 363 Query: 1363 ENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQE 1421 +N G V I P P I I S + + C P I++ + Q Sbjct: 364 QNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKC---PVAGYPIDKIHWERDGQT 420 Query: 1422 IDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ 1480 + + N T +Q L+ +Y A + + T V E ++ Sbjct: 421 LPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMA--------QNKQKQTSRRNV--EIQVL 470 Query: 1481 SPTVEKPLKNITTEPNEDIE--LTC-IFGGVPQPKVTWYRDGKKL-----KTAKATYENR 1532 P P++ +T E + ++C I G W R+GK L + + E Sbjct: 471 VPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYS 530 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y CIA N G + + + P + +D + G + L+ Sbjct: 531 ASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKD--SSAQAGADVLL 588 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKE---YNITTKE-KTSVIRIKELKRSHSSKYTIEAS 1648 G P P + W K + + Y T + I K++ + + EA Sbjct: 589 HCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAK 648 Query: 1649 NTAGTSSVEVTLKVYDKPSKPEGPVIMREISR-ESVTIEWKPPLDDGGLELTKYAIEKHE 1707 N G+ +V + P+ + +++ + V ++ D+ K + Sbjct: 649 NNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQQY 708 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRV---IAQNPVGFSEALESEPIVIKTAL 1764 D + + D+ ++ + +L + Y I Q F + S ++++ Sbjct: 709 LDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVP 768 Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXA 1824 + P + S+ +TW G SPI +Y + KQ W+ A Sbjct: 769 EQPKNLRINSQ----QSRSLQLTW-SQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAGA 823 Query: 1825 R----IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE-STS 1879 + IQ+L Y R+ A N++G S ++ ++T + + PS P V +E +S Sbjct: 824 QTVINIQQLRPAKAYHIRMSAENKLGAS-EFSEVVQVTTLEEV--PSGPPLAVRAEPKSS 880 Query: 1880 RSVTLKWTEPESNGGSPIT-NYII--------EFKTVKGKSWTKIVTVGGSVH---EHCI 1927 + + W PE + + I Y + E K V TV H E + Sbjct: 881 TEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVL 940 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 N+ + + + A + G P S+ + ++ VPS P + ++GS + +W Sbjct: 941 ANLNKFTQYHVIVQAYTSQGSGPP--SKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITW 998 Query: 1988 GTPEWDG-GAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 P+ DG + GY + V + + V I +L + Y + + A + Sbjct: 999 SPPDIDGQNGKIKGYKVFYISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTK 1058 Query: 2047 IG 2048 +G Sbjct: 1059 VG 1060 Score = 74.9 bits (176), Expect = 2e-11 Identities = 106/431 (24%), Positives = 171/431 (39%), Gaps = 52/431 (12%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 QF+C V G+P + W I ++ D L+I++V ED G + C N Sbjct: 210 QFQCIVSGHPVHDVNWLHDGKPILRDNRVEILTDPPR---LIIKKVQKEDPGMYQCFVSN 266 Query: 588 AAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDE 647 ST EL L D E+ + G PT S K V Sbjct: 267 EWEQIQSTAEL----QLGDASPELLYWFSEQT--------LQPG--PTVSLK----CVAT 308 Query: 648 GSDI-LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 G+ + L P PD + G+ V I D+ S + I+NVK+ G Sbjct: 309 GNPLPQFTWSLDGFPIPDSSRFLVGQ--------YVTIHDDV---ISHVNISNVKEEDGG 357 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTI 766 YT A N G+ S K P + E K + G +I+ V G P I Sbjct: 358 EYTCTAQNAIGKVS----HSAKVNIYGLPYIREMPKITGI-SGSDLIVKCPVAGYPIDKI 412 Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W ++ + + + + ++ I + ++++D G YT A+N + +TS Sbjct: 413 HWERDGQTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQ--KQTS-----RRNV 465 Query: 827 EENAEPPLFINRFQEIT--VKEKGTIKLVARVTRNPVP-SITWYRNNE-IISPSETITQN 882 E P I Q +T ++E + ++ +P S W RN + +I + + Sbjct: 466 EIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRR 525 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 D + LVI ++ S+ SG+Y C+ASN AG +T++V ++ K + Sbjct: 526 LDEYSASLVIEHISSD-HSGNYTCIASNVAGTERFTVPLTVNVPPKWILE--PKDSSAQA 582 Query: 943 GKTVILECQTS 953 G V+L CQ+S Sbjct: 583 GADVLLHCQSS 593 Score = 68.5 bits (160), Expect = 2e-09 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 10/196 (5%) Query: 1855 DKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK 1914 D+I + P + N V + + S+ L+W + S+GGSPI Y+I +K G W + Sbjct: 1255 DEIVYNIVVKVPPEAPNLTVINAYTDSLLLEWMD-NSHGGSPILGYVINYKRDNG-DWEE 1312 Query: 1915 IVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE 1974 + V H + N+ I+A N +G LP + + T +PP P Sbjct: 1313 L-QVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCD-----IVNSYTKGNPPVQPKH 1366 Query: 1975 IRMVGSNIV-MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK-VDVNTLKFNIRDLS 2032 +M+ +N +T W DGG +L + I R ++ W V + + + DL Sbjct: 1367 SQMITNNSTSVTCWLDSWGDGGCGILYFMIESRVYGRSSWAVVSNHIPPTERIYTVSDLV 1426 Query: 2033 ENHTYMIRIYARNEIG 2048 Y +++ A N G Sbjct: 1427 PGTKYQLKVTAHNNAG 1442 Score = 65.3 bits (152), Expect = 2e-08 Identities = 83/382 (21%), Positives = 140/382 (36%), Gaps = 16/382 (4%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPE-NTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 D PS P + SS I I W P+ G+ T + + E E + + Sbjct: 1075 DVPSAPQAIKAIPASSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGPFV 1134 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNE 1497 + ++T S ++ + + + E T+ V K+ + V + I T E Sbjct: 1135 EMHETVRTQESATYQFWLTASTKMGEG-EKTQVVTVPPNNKVPARIVSFS-QRIVTPWKE 1192 Query: 1498 DIELTCIFGGVPQPKVTWYRDGKKLKT-AKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 +EL C G P P W +DG ++T A+ T Y C N Sbjct: 1193 HLELPCRKVGAPAPVTIWRQDGHNMETSARKTIAKNGTLYMKECQASDAGNYTCSVENTW 1252 Query: 1557 G--EVETSCVVGI-QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 G E+ + VV + + P +T+ N + EW+ + G P ++ Y K Sbjct: 1253 GKDEIVYNIVVKVPPEAPNLTVIN---AYTDSLLLEWMDNS--HGGSP--ILGYVINYKR 1305 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 +N + KT+ + L + I A N GT + Y K + P P Sbjct: 1306 DNGDWEELQVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGNPPVQPK 1365 Query: 1674 IMREISRESVTIE-WKPPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKL 1731 + I+ S ++ W DGG + + IE + W V++ + Y + L Sbjct: 1366 HSQMITNNSTSVTCWLDSWGDGGCGILYFMIESRVYGRSSWAVVSNHIPPTERIYTVSDL 1425 Query: 1732 NENCEYMFRVIAQNPVGFSEAL 1753 +Y +V A N G + A+ Sbjct: 1426 VPGTKYQLKVTAHNNAGSTTAI 1447 Score = 65.3 bits (152), Expect = 2e-08 Identities = 43/168 (25%), Positives = 77/168 (45%), Gaps = 7/168 (4%) Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARI-QKLSINTTYQFRIY 1840 +S+ + W + +GGSPI+ Y + K++ W+ + + L T YQ I Sbjct: 1280 DSLLLEWMDNS-HGGSPILGYVINYKRDNGDWEELQVDSKTTSHLLTNLWCGTRYQLYIT 1338 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N+IGT LP + T G PP QP++ + + S SVT W + +GG I + Sbjct: 1339 AYNKIGTGLPCDIVNSYTKG---NPPVQPKHSQMITNNSTSVTC-WLDSWGDGGCGILYF 1394 Query: 1901 IIEFKTVKGKSWTKIVT-VGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 +IE + SW + + + + + ++ + +++A N G Sbjct: 1395 MIESRVYGRSSWAVVSNHIPPTERIYTVSDLVPGTKYQLKVTAHNNAG 1442 Score = 57.2 bits (132), Expect = 5e-06 Identities = 104/465 (22%), Positives = 172/465 (36%), Gaps = 44/465 (9%) Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV--I 1605 Y C A N G+ E S + +Q+ P N I + + + G P E I Sbjct: 745 YICQASNAFGQDEMSIQLIVQEVPEQP-KNLRINSQQSRSLQLTWSQPFAGNSPIEEYHI 803 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 +YK + + + E+ +T +VI I++L+ + + + A N G S ++V Sbjct: 804 YYKQISDIWQNAEH-LTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTL 862 Query: 1666 PSKPEGPVIMREISRESVT---IEWKPPLDD--GGLELTKYA---------IEKHEPDNN 1711 P GP + +S T + W P D G+ L Y ++ P Sbjct: 863 EEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQG 922 Query: 1712 RWIKVADVDRDV--ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 K +V ET + LN+ +Y VI Q S+ I ++T DVPS Sbjct: 923 FSFKTVEVRSHFGGETV-LANLNKFTQY--HVIVQAYTSQGSGPPSKEIAVQTMEDVPSS 979 Query: 1770 XXXXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKV---EIKQEGKKWKXXXXXXXXXAR 1825 + + S+YITW P + +G I YKV + + + Sbjct: 980 PPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFYISVDELYETDPEVVKSTNQYVT 1039 Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 I+ L T Y + A ++G + T + + PS P+ ++S + + Sbjct: 1040 IENLRKYTNYTVWVLAYTKVGDGMK-TKPFYCRTHEDV--PSAPQAIKAIPASSSKIIIS 1096 Query: 1886 WTEPESNGGSPITNYIIEFKTVKG--KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 W P+ G IT Y ++G + T +G V H +E F ++A Sbjct: 1097 WLPPDLPNGD-ITGYTFYMSMLEGGREEGTHKRLLGPFVEMHETVRTQESATYQFWLTAS 1155 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG-SNIVMTSW 1987 +G EK V PP + R+V S ++T W Sbjct: 1156 TKMGEG----------EKTQVVTVPPNNKVPARIVSFSQRIVTPW 1190 Score = 52.8 bits (121), Expect = 1e-04 Identities = 55/247 (22%), Positives = 92/247 (37%), Gaps = 19/247 (7%) Query: 595 TTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLE 654 + L++E SDH T + +PP + +PK G+D+LL Sbjct: 530 SASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLH 589 Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGTYTVVAV 713 C+ P P I W K P E E + ++ + + + K +G + A Sbjct: 590 CQSSGYPTPTITWK-KAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAK 648 Query: 714 NREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW---C 769 N G S I LK+ P K + V +G+ V + V G+ W Sbjct: 649 NNIGSGVSKVIFLKVNV----PAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQA 704 Query: 770 KNNKPVKALPTK--------SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 ++L ++ DG + I + +D G+Y +A N+ G E S + Sbjct: 705 TQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYR-QDTGIYICQASNAFGQDEMSIQLI 763 Query: 822 VEEPTEE 828 V+E E+ Sbjct: 764 VQEVPEQ 770 Score = 52.4 bits (120), Expect = 1e-04 Identities = 42/166 (25%), Positives = 79/166 (47%), Gaps = 14/166 (8%) Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 +K+ +L +K+ + +DAG Y +EN G ++ N+ + PP PN+ I++ + ++ Sbjct: 1226 AKNGTLYMKECQASDAGNYTCSVENTWGKDEIVYNIVV---KVPPEAPNLTVINAYTDSL 1282 Query: 1400 CWDEPENT-GNSTIIYYVVEYQEIDTTEWISVKNITKTQTS-IQNLKTNSSYRFRAYAVN 1457 + +N+ G S I+ YV+ Y+ D +W ++ +KT + + NL + Y+ A N Sbjct: 1283 LLEWMDNSHGGSPILGYVINYKR-DNGDWEELQVDSKTTSHLLTNLWCGTRYQLYITAYN 1341 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTC 1503 ++ + Y TK P K + IT N +TC Sbjct: 1342 KIGTGLPCDIVNSY-----TKGNPPVQPKHSQMIT---NNSTSVTC 1379 Score = 50.8 bits (116), Expect = 4e-04 Identities = 86/414 (20%), Positives = 159/414 (38%), Gaps = 28/414 (6%) Query: 1648 SNTAGTSSVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPP-LDDGGLELTKYAIEK 1705 S +G S E+ ++ D PS P + S+ I W PP +D ++ Y + Sbjct: 958 SQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFY 1017 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALD 1765 D V + I+ L + Y V+A VG + ++++P +T D Sbjct: 1018 ISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVG--DGMKTKPFYCRTHED 1075 Query: 1766 VPSXXXXXXXXXXIDNESVYITWFPSE-KNGGSPIIDYKVEIKQEGKK---WKXXXXXXX 1821 VPS + + I+W P + NG + + + + G++ K Sbjct: 1076 VPSAPQAIKAIPA-SSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGPFV 1134 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + + TYQF + A ++G +T+ P++ +F T Sbjct: 1135 EMHETVRTQESATYQFWLTASTKMGEG---EKTQVVTVPPNNKVPARIVSFSQRIVTPWK 1191 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 L+ + +P+T + + ++ S K + G+++ ++ + D + S Sbjct: 1192 EHLELPCRKVGAPAPVTIWRQDGHNME-TSARKTIAKNGTLY---MKECQASDAGNYTCS 1247 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLG 2000 ENT G + + V PP AP L + ++ ++ W GG+P+LG Sbjct: 1248 VENTWGKD--------EIVYNIVVKVPPEAPNLTVINAYTDSLLLEW-MDNSHGGSPILG 1298 Query: 2001 YNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLE 2054 Y I + W E+ +VD T + +L Y + I A N+IG P + Sbjct: 1299 YVINYKR-DNGDWEEL-QVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCD 1350 Score = 46.0 bits (104), Expect = 0.011 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF----QMYYDDDNVATLVIREVFPEDAG 579 G TV +C G P PQ TW I S F + DD ++ + I V ED G Sbjct: 298 GPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGG 357 Query: 580 TFTCVAKNAAGFASSTTEL 598 +TC A+NA G S + ++ Sbjct: 358 EYTCTAQNAIGKVSHSAKV 376 Score = 41.5 bits (93), Expect = 0.25 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 6/72 (8%) Query: 518 PKHTP-DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFP- 575 PK T GS + +C V GYP +I W R + ++ + Y N TL+I ++ Sbjct: 388 PKITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAY----NNGTLIIEQLQRL 443 Query: 576 EDAGTFTCVAKN 587 EDAGT+TC+A+N Sbjct: 444 EDAGTYTCMAQN 455 Score = 40.3 bits (90), Expect = 0.57 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 2/98 (2%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLV 569 I VEK +H C +G+P P WF++ + P Q + L Sbjct: 99 INVEKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFKEENEQLLPLQ-LSERITIVSAGLLK 157 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 I + ED+G + C N AG + L V APL+ H Sbjct: 158 ITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAH 195 Score = 40.3 bits (90), Expect = 0.57 Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 3/130 (2%) Query: 700 VKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 V+ + TY + A + GE V+ + K P +++ + ++ E + L + Sbjct: 1140 VRTQESATYQFWLTASTKMGEGEKTQVVTVPPNNKVPARIVSFSQRIVTPWKEHLELPCR 1199 Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETS 817 VG P P W ++ ++ K+ ++ +K + D G YT EN+ G E Sbjct: 1200 KVGAPAPVTIWRQDGHNMETSARKTIAKNGTL-YMKECQASDAGNYTCSVENTWGKDEIV 1258 Query: 818 AVITVEEPTE 827 I V+ P E Sbjct: 1259 YNIVVKVPPE 1268 Score = 39.5 bits (88), Expect = 0.99 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 11/152 (7%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV- 565 ++ P ++ + + G+ V CQ GYP P ITW + AI +++ + + V Sbjct: 566 NVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITW--KKAIGPTPGEYKDFLYEPTVQ 623 Query: 566 ----ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 T+ +++ E G F C AKN G S + ++ + H T Sbjct: 624 LFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKV-IFLKVNVPAHFQTKTKQISVAKGK 682 Query: 622 XXXXADILEGIPP-TFSKKPKA--QYVDEGSD 650 ++G P F K +A QY+DE D Sbjct: 683 QVHVQCNVQGDNPIDFKWKIQATQQYLDESLD 714 Score = 37.5 bits (83), Expect = 4.0 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G CQ+ EG W R + + + D+ A+LVI + + +G + Sbjct: 487 EGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNY 546 Query: 582 TCVAKNAAGFASSTTELIVEAP 603 TC+A N AG T L V P Sbjct: 547 TCIASNVAGTERFTVPLTVNVP 568 >UniRef50_Q696W0 Cluster: Striated muscle preferentially expressed protein kinase; n=7; Danio rerio|Rep: Striated muscle preferentially expressed protein kinase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 2995 Score = 100 bits (239), Expect = 5e-19 Identities = 85/390 (21%), Positives = 156/390 (40%), Gaps = 17/390 (4%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P + + + G + L P P W N K I+ K + SL I Sbjct: 840 PDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVI 899 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTI-LDKPSPPGKPNILE-IDSSSINICWDEPE 1405 + V + +G+YK + N G A ++ + + P PP P ++E + I + W +P+ Sbjct: 900 QSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPK 959 Query: 1406 NTGNS---TIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 N S + YVV+ Q + +T+W ++ ++T T ++ +L Y FR + + Sbjct: 960 NLDPSIDPASLMYVVQQQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTL 1019 Query: 1462 SDASETTEYYKVIKETKI--QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 S S+ T+ +++ + ++P + + N+ + +T V Q TW R G Sbjct: 1020 SKPSQPTDLVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTITITINHV-QATCTWKRRG 1078 Query: 1520 ----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI--AFNDHGEVETSCVVGIQQKPVI 1573 KL + T + + I A N +G + + I P+ Sbjct: 1079 VVLVNKLGALEMTTPDDDQHALHIAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIF 1138 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIK 1633 ED+ VG+ V++G P P+++WYK+G L ++ + + Sbjct: 1139 ETIMEDLDVC--VGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVL 1196 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 + YT A N AG+ S + L V+ Sbjct: 1197 NAQPEDVGVYTCTAKNLAGSVSCKAELTVH 1226 Score = 97.5 bits (232), Expect = 4e-18 Identities = 71/263 (26%), Positives = 117/263 (44%), Gaps = 11/263 (4%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S P+F KL +G + QF+C+V G P P++TW + S + + + + Sbjct: 711 SKEPLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHI-LNVNGHH 769 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXX 623 +L+I V E G +T +A+N G A+S+ EL V+ P +S H S + Sbjct: 770 SLLITHVNKESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEV 829 Query: 624 XXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA 683 ++ P F K V EG + +L+CR+ +P P I W G++I + + Sbjct: 830 PEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMT 889 Query: 684 IESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKS 743 D+H L I +V G Y V N+ G+A+ L + EPP ++S Sbjct: 890 QYRDVHS----LVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIES 945 Query: 744 MIVRQGESVILSAQVVGNPRPTI 766 + G ++LS + N P+I Sbjct: 946 V---TGRMILLSWKKPKNLDPSI 965 Score = 77.4 bits (182), Expect = 4e-12 Identities = 88/311 (28%), Positives = 130/311 (41%), Gaps = 38/311 (12%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G LLEC + D+ WL G+ I P ++ D H C +L + + Sbjct: 629 VKAGETALLECFIAGSQAVDVDWLANGKLIQP-ALFDCKMQFDGHR-CRLL-FKSAHEND 685 Query: 705 EGTYTV-VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G YT ++ +E +L I + E + +E L+++ +G S +V G P Sbjct: 686 SGCYTCKLSTAKEELICTANLLVIPSKEPLFTRKLEVLEAI---EGRSAQFDCKVSGCPP 742 Query: 764 PTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 P +TW KP+ + + HS+ I K + EG+YT A+N G A +SA + Sbjct: 743 PEVTWTHCEKPLVESDNIHILNVNGHHSLLITHVNK-ESEGLYTAIAQNVHGKAASSAEL 801 Query: 821 TVEEP-----------------TEENAEP---------PLFINRFQEITVKEKGTIKLVA 854 V+EP EE P P FI ++ V E L Sbjct: 802 YVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKC 861 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 RVT P P ITWY N + I + + LVI +V + SG YKCV SN GK Sbjct: 862 RVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVIQSVCHD-HSGVYKCVISNKVGK 920 Query: 915 SSHGARVTIDV 925 ++ A + + V Sbjct: 921 AACYAHLYVAV 931 Score = 72.5 bits (170), Expect = 1e-10 Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 5/161 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G E ++ + G+P P++ WY NG K+E+ + +T + I+ + HS Y Sbjct: 854 GKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSLVIQSVCHDHSGVYKCV 913 Query: 1647 ASNTAGTSSVEVTLKV-YDKPSKPEGPVIMREISRESVTIEWKPPLD-DGGLELTK--YA 1702 SN G ++ L V P P+GP ++ ++ + + WK P + D ++ Y Sbjct: 914 ISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPKNLDPSIDPASLMYV 973 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIA 1743 +++ + +W +A D +Y + L++ Y FRV++ Sbjct: 974 VQQQVLGSTQWTTIASSLTDT-SYTVTSLSKGVCYSFRVLS 1013 Score = 69.7 bits (163), Expect = 8e-10 Identities = 82/343 (23%), Positives = 130/343 (37%), Gaps = 67/343 (19%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQ-DFQMYYDDDNVATLVIREVFPEDAGTFT 582 G T EC + G + W +I+P+ D +M +D L+ + D+G +T Sbjct: 632 GETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHR-CRLLFKSAHENDSGCYT 690 Query: 583 CVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 C A ELI A L ++ P F++K + Sbjct: 691 CKLSTAK------EELICTANLL----------------------VIPSKEPLFTRKLEV 722 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 EG +C++ P P++ W + +V +NI + + H L IT+V K Sbjct: 723 LEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILNVNGHHS----LLITHVNK 778 Query: 703 FQEGTYTVVAVNREGEA--------------------------SLPIVLKIKTGEKEP-- 734 EG YT +A N G+A S+P ++ GE E Sbjct: 779 ESEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSRLEKMPSIPEEPEVPEGEVERRT 838 Query: 735 -PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK---SDGDTHSIT 790 P I+PL + V +G+ +L +V G P P ITW N K +++ + D HS+ Sbjct: 839 MPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIESTNDRKMTQYRDVHSL- 897 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 +++ GVY N G A A + V E + P Sbjct: 898 VIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPEPPDGP 940 Score = 67.7 bits (158), Expect = 3e-09 Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 17/234 (7%) Query: 712 AVNREGEASLPIVLKIKTGEKEPPQ----VIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 A+ G L ++K T + P + + P++ + V+ GE+ +L + G+ + Sbjct: 591 ALGTAGSELLQCIIKENTVARAPAESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVD 650 Query: 768 WCKNNKPVK--ALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENS-EGIAETSAVITVE 823 W N K ++ K D H +L K D G YT K + E + T+ ++ + Sbjct: 651 WLANGKLIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTANLLVI- 709 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI-TQN 882 P++E PLF + + + E + + +V+ P P +TW + + S+ I N Sbjct: 710 -PSKE----PLFTRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILN 764 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 +G + L+IT+V+ E G Y +A N GK++ A + + + H+ + Sbjct: 765 VNGHH-SLLITHVNKE-SEGLYTAIAQNVHGKAASSAELYVQEPRPAISTHMSR 816 Score = 63.7 bits (148), Expect = 5e-08 Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 1/94 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 ++ PIF + G T F V+G P P I W++ ++ S YDD Sbjct: 1133 AVPPIFETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRE-C 1191 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +LV+ PED G +TC AKN AG S EL V Sbjct: 1192 SLVVLNAQPEDVGVYTCTAKNLAGSVSCKAELTV 1225 Score = 62.1 bits (144), Expect = 2e-07 Identities = 53/214 (24%), Positives = 96/214 (44%), Gaps = 11/214 (5%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK--HTKPSIDSKS 1342 +FPP +++ + G+ VTL P+P W+ + K +K C + + D + Sbjct: 2321 DFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQ 2380 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWD 1402 L I + DAGIY+ NN +T+ P+ PG P I +I ++++ + W Sbjct: 2381 L-LMIMNISKKDAGIYECVATNNLASVTTSCILTLACIPNCPGTPEIRQIYNNTVLVQW- 2438 Query: 1403 EPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 +P +T Y +E + +W++ +T + L + S+ RFR VN+ Sbjct: 2439 KPSDT--KVPCTYTIEKKFDGDDKWLTEATGVTDCFFNSSELPSGSTIRFRVACVNKAGQ 2496 Query: 1462 SDASETTEYYKVIKETKIQSPTVEKPLKNITTEP 1495 S S ++ + +TK+ +P +P K T P Sbjct: 2497 SPYSNESDGVSI--DTKV-TPQ-HQPAKMKTHSP 2526 Score = 61.3 bits (142), Expect = 3e-07 Identities = 62/252 (24%), Positives = 104/252 (41%), Gaps = 25/252 (9%) Query: 723 IVLKIKTGE--KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN-----NKPV 775 +V + GE ++ P +I+ + + + V ++ + + + T TW + NK Sbjct: 1028 LVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTITI-TINHVQATCTWKRRGVVLVNKLG 1086 Query: 776 KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF 835 T D D H++ I K K D G A N G + + + A PP+F Sbjct: 1087 ALEMTTPDDDQHALHIAKVKST-DVGQLIFMANNQYGSDLGTLQLVI-------AVPPIF 1138 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV 895 +++ V T V P P I WY++ +++ S +T +D LV+ N Sbjct: 1139 ETIMEDLDVCVGETCHFAVVVDGKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVLNA 1198 Query: 896 DSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT 955 E D G Y C A N AG S A +T+ +++++ E E + IL Sbjct: 1199 QPE-DVGVYTCTAKNLAGSVSCKAELTVHT-----AQNVEEEEEQMEDEATILR---RMR 1249 Query: 956 VSTKWYHNKKEI 967 + T +Y KEI Sbjct: 1250 MLTDYYDIHKEI 1261 Score = 58.4 bits (135), Expect = 2e-06 Identities = 54/210 (25%), Positives = 98/210 (46%), Gaps = 13/210 (6%) Query: 996 VIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE 1054 +++CI+K E + E++ R +QD +VK + A+LE I S+ DV W +G+ Sbjct: 599 LLQCIIK--ENTVARAPAESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVDWLANGK 656 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL---RDE-SCTAEVTVVELPPEII 1110 +I+P + GH +L ++ +D G Y+C L ++E CTA + V+ + Sbjct: 657 LIQPALFDCKMQFDGHRCRLLFKSAHENDSGCYTCKLSTAKEELICTANLLVIPSKEPLF 716 Query: 1111 TR-LQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDC 1168 TR L+ + +G A F+ +++ V W + S++I + L I Sbjct: 717 TRKLEVLEAIEGRSAQFDCKVSGCPPPEVTWTHCEKPLVESDNIHILNVNGHHSLLITHV 776 Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVEEP 1194 + + G Y+ G + +A L V+EP Sbjct: 777 NKESEGLYTAIAQNVHGKAASSAELYVQEP 806 Score = 57.2 bits (132), Expect = 5e-06 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 3/119 (2%) Query: 490 EKIDKLPVF-EKPTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT 547 EK+ +P E P E E+ P F++ L +G +C+V G P P+ITW+ Sbjct: 818 EKMPSIPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNG 877 Query: 548 AIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 I+ + D +M D V +LVI+ V + +G + CV N G A+ L V L + Sbjct: 878 KKIESTNDRKMTQYRD-VHSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPE 935 Score = 50.0 bits (114), Expect = 7e-04 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Query: 491 KIDKLPVFEK-PTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 K D+ P + P + ++ P+F L+ +G+ V C G P P+I W + Sbjct: 2304 KRDRTPSNSRAPATPKEDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKP 2363 Query: 550 IKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +K + D L+I + +DAG + CVA N AS TT I+ Sbjct: 2364 LKLCDGMNLEACPDGRQLLMIMNISKKDAGIYECVATN--NLASVTTSCIL 2412 Score = 49.2 bits (112), Expect = 0.001 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 5/96 (5%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 PP + LK V G V L V GNPRPT+ W N+ P+ D + + ++ Sbjct: 27 PPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDDPLVI-----DHEDYDGLWIR 81 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 + D G+YT A N G A TSAV+ V + E++ Sbjct: 82 DCQQADGGLYTCVAVNHLGEARTSAVLAVLDLEEDS 117 Score = 49.2 bits (112), Expect = 0.001 Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPTKSDGDTH 787 E PP LK ++ +G V LS G+P P I W K+ KP+K + ++ D Sbjct: 2320 EDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGR 2379 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 + ++ KD G+Y A N+ TS ++T+ Sbjct: 2380 QLLMIMNISKKDAGIYECVATNNLASVTTSCILTL 2414 Score = 48.4 bits (110), Expect = 0.002 Identities = 43/178 (24%), Positives = 78/178 (43%), Gaps = 7/178 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI-TTKEKTSVIRIKELKRSHSSKYTI 1645 G+ ++ + G P P+++W K+ L+ N+ + ++ I + + + Y Sbjct: 2338 GNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQLLMIMNISKKDAGIYEC 2397 Query: 1646 EASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEK 1705 A+N + + L + P+ P P I R+I +V ++WKP D + T Y IEK Sbjct: 2398 VATNNLASVTTSCILTLACIPNCPGTPEI-RQIYNNTVLVQWKP--SDTKVPCT-YTIEK 2453 Query: 1706 HEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKT 1762 +++W+ A D + +L FRV N G S + ES+ + I T Sbjct: 2454 KFDGDDKWLTEATGVTDC-FFNSSELPSGSTIRFRVACVNKAGQSPYSNESDGVSIDT 2510 Score = 44.0 bits (99), Expect = 0.046 Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 5/89 (5%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-----TAKATYENRXXXX 1536 P LK+ + L+C+ G P+PK+ W +D K LK +A + R Sbjct: 2324 PVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQLLM 2383 Query: 1537 XXXXXXXXXXXYKCIAFNDHGEVETSCVV 1565 Y+C+A N+ V TSC++ Sbjct: 2384 IMNISKKDAGIYECVATNNLASVTTSCIL 2412 Score = 43.6 bits (98), Expect = 0.061 Identities = 37/151 (24%), Positives = 60/151 (39%), Gaps = 5/151 (3%) Query: 830 AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE-TITQNFDGEN 887 AE L I R Q++ VK T L + + + W N ++I P+ FDG Sbjct: 614 AESLLIITRPMQDVKVKAGETALLECFIAGSQAVDVDWLANGKLIQPALFDCKMQFDGHR 673 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 L+ + E DSG Y C S + + A + + K + E EG++ Sbjct: 674 CRLLFKSAH-ENDSGCYTCKLSTAKEELICTANLLVIPSKEPLFTRKLEVLEAIEGRSAQ 732 Query: 948 LECQTS--HTVSTKWYHNKKEISGMDHREII 976 +C+ S W H +K + D+ I+ Sbjct: 733 FDCKVSGCPPPEVTWTHCEKPLVESDNIHIL 763 Score = 43.2 bits (97), Expect = 0.081 Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 8/91 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P+F+ KL+ G V+ V G PRP + W+ D + D ++ L Sbjct: 28 PVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYH--------NDDPLVIDHEDYDGLW 79 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 IR+ D G +TCVA N G A ++ L V Sbjct: 80 IRDCQQADGGLYTCVAVNHLGEARTSAVLAV 110 Score = 40.7 bits (91), Expect = 0.43 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 9/99 (9%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 A PP+F+ + + V ++L V NP P++ WY N++ P +++DG Sbjct: 25 AAPPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDD---PLVIDHEDYDG---- 77 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEK 927 L I + + D G Y CVA N G++ A + + D+E+ Sbjct: 78 LWIRDC-QQADGGLYTCVAVNHLGEARTSAVLAVLDLEE 115 Score = 39.9 bits (89), Expect = 0.75 Identities = 28/114 (24%), Positives = 53/114 (46%), Gaps = 6/114 (5%) Query: 1000 IVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKP 1058 I ++ E V + T+P+FI+ L D EV E A+L+ + + W +G+ I+ Sbjct: 823 IPEEPEVPEGEVERRTMPDFIKPLSDLEVIEGKEAVLKCRVTGLPYPKITWYHNGKKIES 882 Query: 1059 KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE----SCTAEVTVVELPPE 1108 ++ + R + L I++ G Y C++ ++ +C A + V PE Sbjct: 883 TNDRKMTQYR-DVHSLVIQSVCHDHSGVYKCVISNKVGKAACYAHLYVAVSLPE 935 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/98 (26%), Positives = 40/98 (40%), Gaps = 3/98 (3%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E PP F K + EG+ + L C PEP I WL + + + +++ D Sbjct: 2320 EDFPPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGR 2379 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 +L I N+ K G Y VA N + +L + Sbjct: 2380 ---QLLMIMNISKKDAGIYECVATNNLASVTTSCILTL 2414 Score = 39.1 bits (87), Expect = 1.3 Identities = 40/196 (20%), Positives = 78/196 (39%), Gaps = 13/196 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSE-IQFSNHIQLTI-DGKKQKLK 1164 P+I+ ++NQ V T I + A W + G + +++T D + L Sbjct: 1048 PDIVYAVENQPV------TITITINHVQATCTWKRRGVVLVNKLGALEMTTPDDDQHALH 1101 Query: 1165 IYDCDLDDAGEY----SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEI 1220 I D G+ + + G+ T L + P I T+ + + + T + V Sbjct: 1102 IAKVKSTDVGQLIFMANNQYGSDLGTLQLVIAVPPIFETI-MEDLDVCVGETCHFAVVVD 1160 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 D+ WYK ++ ++ T + D ++ +L++ +D YTC + + K Sbjct: 1161 GKPDPDILWYKDGVLLAESSHLTFVYDDRECSLVVLNAQPEDVGVYTCTAKNLAGSVSCK 1220 Query: 1281 VEVVEFPPKIVDYERE 1296 E+ + V+ E E Sbjct: 1221 AELTVHTAQNVEEEEE 1236 Score = 37.1 bits (82), Expect = 5.3 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 11/101 (10%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F +K K V G D+ L + P P + W + +V D H Sbjct: 27 PPVFLRKLKWAAVAAGCDVRLRVCVGGNPRPTLHWYHNDDPLVID-----------HEDY 75 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKE 733 L I + ++ G YT VAVN GEA VL + E++ Sbjct: 76 DGLWIRDCQQADGGLYTCVAVNHLGEARTSAVLAVLDLEED 116 Score = 36.3 bits (80), Expect = 9.2 Identities = 32/143 (22%), Positives = 65/143 (45%), Gaps = 9/143 (6%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF--DGENIE 889 PP+F ++ + E + L +P P I W ++ + + + + DG + Sbjct: 2323 PPVFHIALKDHVLLEGNPVTLSCLPAGSPEPKILWLKDKKPLKLCDGMNLEACPDGRQL- 2381 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-VEKVTFVKHLQKSYETEEGKTVIL 948 L+I N+ S+ D+G Y+CVA+N+ + +T+ + +++ Y TV++ Sbjct: 2382 LMIMNI-SKKDAGIYECVATNNLASVTTSCILTLACIPNCPGTPEIRQIY----NNTVLV 2436 Query: 949 ECQTSHTVSTKWYHNKKEISGMD 971 + + S T Y +K+ G D Sbjct: 2437 QWKPSDTKVPCTYTIEKKFDGDD 2459 >UniRef50_UPI00015B5045 Cluster: PREDICTED: similar to receptor tyrosine phosphatase type r2a; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to receptor tyrosine phosphatase type r2a - Nasonia vitripennis Length = 2046 Score = 99 bits (238), Expect = 7e-19 Identities = 137/630 (21%), Positives = 238/630 (37%), Gaps = 36/630 (5%) Query: 1436 TQTSIQNLKTN-SSYRFRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITT 1493 T I+ +++N + + A N V D A+ + Y+V K K + P + Sbjct: 98 TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVV- 156 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCI 1551 E + +L+C G P P ++W R+ + T+ Y Y+C+ Sbjct: 157 EKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYECV 216 Query: 1552 AFNDHG-EVETSCVVGIQQKPVIT-ISNE-DIKQKHKVGDEWLVTAVIEGIPPPEVIWYK 1608 A N G E S + ++ + V+ S + D + +G+ +T V G P P V W K Sbjct: 217 ATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRK 276 Query: 1609 N-GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 L D + K +V+ +K + S+ YT A + G + +KV P Sbjct: 277 EPATDLTPDNQMPPIGK---NVLHLKNV--HESANYTCIAQSDLGVINTTTYVKVRSLPL 331 Query: 1668 KPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC 1727 PE V + EI+ SV + W G E Y + +H+P + Y Sbjct: 332 APEN-VQVSEITATSVKLTWSYK----GPESLAYYVIQHKPKHAHQAYAEISGITTMYYM 386 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYIT 1787 ++ L+ EY F VIA N +G S P+V+ T P + + + I Sbjct: 387 VRSLSPYTEYEFFVIAVNDIG--RGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTALIQ 444 Query: 1788 WFPSEKNGGSPIIDYKV----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 W E G + YKV + Q W+ I L+ + Y R+ A Sbjct: 445 WDEPETPNGQ-VTGYKVYYTTDSGQPMSNWQFQTVDNNQLTTISDLTAHAIYTIRVQALT 503 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 +G P +S +I + + PSQP E VTLKW +P + + ++ + Sbjct: 504 SVGPG-PLSSPVQIKTQQGV--PSQPEMLQAVEVGENKVTLKWNKPSISAENILSYELYW 560 Query: 1904 FKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHA 1963 T + + + V + + N+ ++A + G T VR E++ Sbjct: 561 NDTYAQEKHHRKIPV---AENYTLTNLYPNTLYYVWLAARSQRGEGATTIPLPVRTEQY- 616 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 VP P + ++ W P + ++ Y + + ++ E V +N Sbjct: 617 -VPGAPPRNVTGLPTSPTSILVKWEPPPVERSNGRIVYYKLHYVENGRSD-SESSIVTLN 674 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 +F + +L + Y I + A +G P Sbjct: 675 GTEFVLDELKKWTEYRIWVVAGTSVGDGPP 704 Score = 85.8 bits (203), Expect = 1e-14 Identities = 202/998 (20%), Positives = 367/998 (36%), Gaps = 90/998 (9%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQF---SNHIQLTIDGKKQ 1161 PP I + Q+Q V G A+F + + W K+ +I SN + Sbjct: 39 PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGT 98 Query: 1162 KLKIYDCDLD-DAGEYSCEVGNS-----KCTAILTVEE-----PSINFTLRLPEFILVPA 1210 L+I + DA Y C N TA LT+ E + P +V Sbjct: 99 LLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVEK 158 Query: 1211 NTDAYLTVEIPDETLD-VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 +A L+ + ++W + + I+ + ++ ++ L I DDQ +Y CV Sbjct: 159 GHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVV--LESGALQITDSDPDDQGKYECV 216 Query: 1270 LLDAKST-----TKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 ++ T T+L V++ P + + G L P P +W Sbjct: 217 ATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVEVTLGESTNLTCVAYGSPMPYVKWRK 276 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + P I L +K V ++ Y +++ G + V + P Sbjct: 277 EPATDLTPDNQMPPIGKN--VLHLKNVH--ESANYTCIAQSDLGVINTTTYVKVRSLPLA 332 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE-WISVKNITKTQTSIQN 1442 P + EI ++S+ + W G ++ YYV++++ + + + IT +++ Sbjct: 333 PENVQVSEITATSVKLTW---SYKGPESLAYYVIQHKPKHAHQAYAEISGITTMYYMVRS 389 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP---TVEKPLKNITTEPNEDI 1499 L + Y F AVN DI ++ ETK S +PL + T D Sbjct: 390 LSPYTEYEFFVIAVN--DIGRGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTALIQWD- 446 Query: 1500 ELTCIFGGVPQPKVTWYRD-GKKLKTAK-ATYENRXXXXXXXXXXXXXXXYKCIAFNDHG 1557 E G V KV + D G+ + + T +N + A G Sbjct: 447 EPETPNGQVTGYKVYYTTDSGQPMSNWQFQTVDNNQLTTISDLTAHAIYTIRVQALTSVG 506 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQ----KHKVGDEWLVTAV-IEGIPPPEVIW------ 1606 S V I+ + + E ++ ++KV +W ++ E I E+ W Sbjct: 507 PGPLSSPVQIKTQQGVPSQPEMLQAVEVGENKVTLKWNKPSISAENILSYELYWNDTYAQ 566 Query: 1607 YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 K+ K+ + Y +T ++ + RS + A T + V + Y P Sbjct: 567 EKHHRKIPVAENYTLTNLYPNTLYYVWLAARS-------QRGEGATTIPLPVRTEQY-VP 618 Query: 1667 SKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVE 1724 P V S S+ ++W+ PP++ + Y + H +N R + V + Sbjct: 619 GAPPRNVTGLPTSPTSILVKWEPPPVERSNGRIVYYKL--HYVENGRSDSESSIVTLNGT 676 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + + +L + EY V+A VG + S PI ++T DVP I+ ++ Sbjct: 677 EFVLDELKKWTEYRIWVVAGTSVG--DGPPSYPITVRTHEDVPG-DPQNVKATPINATAI 733 Query: 1785 YITWFPSEKNGGSPII-DYKVEIKQEGKKWKXXXXXXXXXARIQK--LSIN-------TT 1834 Y+ W P + + II Y V +++ ++ K +++ L +N T Sbjct: 734 YVEWEPPKSKERNGIIRGYHVHVQEVSEETKNQLNDPIRSISLEEDVLHVNISGLQPDTR 793 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFV--VSESTSRSVTLKWTEPESN 1892 Y ++ A G T G PS+P + +S + L WT P Sbjct: 794 YDVQVAALTRKGDGARSIPVSVKTPGGV---PSRPSLIIKTISREDPIEMQLDWTRPTQT 850 Query: 1893 GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD-EIIFRISAENTVGVSLP 1951 G I Y I + + ++ ++ G SVH + I++++E+ + FR++ +N VG Sbjct: 851 YGQ-ILGYRIRYGII-NQTLKEVFLEGDSVHSYRIKDLEERGVDYEFRVAGKNEVGFG-- 906 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTK 2010 + Q P+ P L + V +W P+ ++ YN+ + Sbjct: 907 -QEQVRNWFSQEGAPTGPPTNLSFHFQTPDTVCVTWDPPQQKFRNGKIVSYNVQFHKKSD 965 Query: 2011 TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 EV + ++ + +L EN Y+ + A G Sbjct: 966 HT-SEVTR-NITKTRAVFTNLDENTEYVFHVKAYTSRG 1001 Score = 75.4 bits (177), Expect = 2e-11 Identities = 82/317 (25%), Positives = 126/317 (39%), Gaps = 34/317 (10%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQT-AIIKPSQDFQ-MYYDDDNVAT 567 P F++K + + +G F C G P PQI W + I+ +Q + M Y +N Sbjct: 40 PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99 Query: 568 LVIREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 L I V DA + C+A+N G A S T + +T+ Sbjct: 100 LRIEPVRSNRDAIAYECLAENGVGDAVSAT------------ASLTI----------YEV 137 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 D L P ++ P + V++G + L C + P P I+W+ I V +ES Sbjct: 138 DKLPKGFPMITQAPTTKVVEKGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLES 197 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMI 745 L+IT+ +G Y VA N G E S L +K P +P + Sbjct: 198 ------GALQITDSDPDDQGKYECVATNSVGTEYSKSTQLYVKIRRVLPHFSRQPDPVVE 251 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 V GES L+ G+P P + W K +P L + +L K V + YT Sbjct: 252 VTLGESTNLTCVAYGSPMPYVKWRK--EPATDLTPDNQMPPIGKNVLHLKNVHESANYTC 309 Query: 806 KAENSEGIAETSAVITV 822 A++ G+ T+ + V Sbjct: 310 IAQSDLGVINTTTYVKV 326 Score = 67.7 bits (158), Expect = 3e-09 Identities = 66/289 (22%), Positives = 118/289 (40%), Gaps = 19/289 (6%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F +KP++Q V G C P P I W ++I+ N S + Sbjct: 39 PPRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIM-STNQSNRFMVYPYENG 97 Query: 693 SVLKITNVKKFQEG-TYTVVAVNREGEA-SLPIVLKIKTGEKEP---PQVIEPLKSMIVR 747 ++L+I V+ ++ Y +A N G+A S L I +K P P + + + +V Sbjct: 98 TLLRIEPVRSNRDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVE 157 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 +G + LS +G+P P I+W +N P+ + + D+G Y A Sbjct: 158 KGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGALQITDSDPDDQGKYECVA 217 Query: 808 ENSEGI---AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 NS G T + + + P + E+T+ E + VA +P+P + Sbjct: 218 TNSVGTEYSKSTQLYVKIRRVLPHFSRQP---DPVVEVTLGESTNLTCVA--YGSPMPYV 272 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 W + P+ +T + I + ++ + +S +Y C+A + G Sbjct: 273 KWRK-----EPATDLTPDNQMPPIGKNVLHLKNVHESANYTCIAQSDLG 316 Score = 56.8 bits (131), Expect = 6e-06 Identities = 92/420 (21%), Positives = 163/420 (38%), Gaps = 38/420 (9%) Query: 1604 VIWYKNGNKLEN---DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEV 1658 +++YK + +EN D E +I T T + + ELK+ + + A + G S + Sbjct: 651 IVYYKL-HYVENGRSDSESSIVTLNGTEFV-LDELKKWTEYRIWVVAGTSVGDGPPSYPI 708 Query: 1659 TLKVY-DKPSKPEGPVIMREISRESVTIEWKPP--LDDGGLELTKYAIEKHEPDN----- 1710 T++ + D P P+ V I+ ++ +EW+PP + G+ + Y + E Sbjct: 709 TVRTHEDVPGDPQN-VKATPINATAIYVEWEPPKSKERNGI-IRGYHVHVQEVSEETKNQ 766 Query: 1711 -NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSX 1769 N I+ ++ DV I L + Y +V A G + S P+ +KT VPS Sbjct: 767 LNDPIRSISLEEDVLHVNISGLQPDTRYDVQVAALTRKG--DGARSIPVSVKTPGGVPSR 824 Query: 1770 -XXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE--IKQEGKKWKXXXXXXXXXARI 1826 D + + W + G I+ Y++ I + K RI Sbjct: 825 PSLIIKTISREDPIEMQLDWTRPTQTYGQ-ILGYRIRYGIINQTLKEVFLEGDSVHSYRI 883 Query: 1827 QKL-SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 + L Y+FR+ +NE+G + + P P N T +V + Sbjct: 884 KDLEERGVDYEFRVAGKNEVGFGQEQVRN---WFSQEGAPTGPPTNLSFHFQTPDTVCVT 940 Query: 1886 WTEPESN-GGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 W P+ I +Y ++F K T VT + N+ E E +F + A Sbjct: 941 WDPPQQKFRNGKIVSYNVQFH--KKSDHTSEVTRNITKTRAVFTNLDENTEYVFHVKAYT 998 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG-SNIVMTSWGTPEWDGGAPLLGYNI 2003 + G +E ++ +K AP+ ++ + S+ W P + G ++GY I Sbjct: 999 SRGGGPYSEKITILTDKDI-----GRAPMSVKAIATSDSSAEVWWEPVPNRG-KIIGYEI 1052 Score = 46.4 bits (105), Expect = 0.009 Identities = 111/487 (22%), Positives = 182/487 (37%), Gaps = 65/487 (13%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKP--KKNK---YDFEKRGH 1070 P FI+K Q VK +A + S + W ++ + I + N+ Y +E Sbjct: 40 PRFIQKPQSQMVKNGGIASFFCSASGSPPPQIFWRKNNKKIMSTNQSNRFMVYPYENGTL 99 Query: 1071 IRKLYIRNTSVHDEGEYSCILRDE-----SCTAEVTVVE---LPP--EIITRLQNQKV-N 1119 +R +R+ D Y C+ + S TA +T+ E LP +IT+ KV Sbjct: 100 LRIEPVRSN--RDAIAYECLAENGVGDAVSATASLTIYEVDKLPKGFPMITQAPTTKVVE 157 Query: 1120 KGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 KG+ A ++ W ++ I SN + ++ L+I D D DD G+Y C Sbjct: 158 KGHNAQLSCSAMGSPMPIISWMRNQLPIDTSNPRYVVLESGA--LQITDSDPDDQGKYEC 215 Query: 1179 EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDET-LDVTWYK------ 1231 NS T + + LP F P D + V + + T L Y Sbjct: 216 VATNSVGTEYSKSTQLYVKIRRVLPHFSRQP---DPVVEVTLGESTNLTCVAYGSPMPYV 272 Query: 1232 --KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVE 1285 +K D + + K L ++ E YTC+ L +TT +KV + Sbjct: 273 KWRKEPATDLTPDNQMPPIGKNVLHLKNVHE--SANYTCIAQSDLGVINTTTYVKVRSLP 330 Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASL 1345 P+ V S++T + E + I K KH + S Sbjct: 331 LAPENVQV---------SEITATSVKLTWSYKGPESLAYYVIQHKPKHAHQAYAEISGIT 381 Query: 1346 T----IKKVENTDAGIYKLRLENNCGHADVEMNVTIL---DKP-SPPGKPNILEIDSSSI 1397 T ++ + + + N+ G V + KP S P + + + S++ Sbjct: 382 TMYYMVRSLSPYTEYEFFVIAVNDIGRGPPSSPVVVTTGETKPGSAPRRVQVRPLSSTTA 441 Query: 1398 NICWDEPENTGNSTIIYYVVEY-----QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFR 1452 I WDEPE T N + Y V Y Q + ++ +V N T+I +L ++ Y R Sbjct: 442 LIQWDEPE-TPNGQVTGYKVYYTTDSGQPMSNWQFQTVDN--NQLTTISDLTAHAIYTIR 498 Query: 1453 AYAVNEV 1459 A+ V Sbjct: 499 VQALTSV 505 >UniRef50_O44928 Cluster: SAX-3; n=3; Caenorhabditis|Rep: SAX-3 - Caenorhabditis elegans Length = 1273 Score = 99.5 bits (237), Expect = 9e-19 Identities = 100/405 (24%), Positives = 158/405 (39%), Gaps = 35/405 (8%) Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 F +P+ G +LEC PEP ++W +E+ + + SD ++ Sbjct: 135 FRVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI--- 191 Query: 695 LKITNVKKFQEGTYTVVAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 I V + GTY VA N GE S P L + E P+ + K M V G +V+ Sbjct: 192 --IDPVDRSDSGTYQCVANNMVGERVSNPARLSVF----EKPKFEQEPKDMTVDVGAAVL 245 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 +V G+P+P ITW + N+P+ D + I + + DEG Y A N G Sbjct: 246 FDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIERVQP-SDEGEYVCYARNPAGT 304 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNE 871 E SA + V+ PP F + + +V GT + P P+ W + + Sbjct: 305 LEASAHLRVQ-------APPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQD 357 Query: 872 IISPSETITQNFDGENIELVITNVD-SEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT- 929 ++ PS + +T + ++D G Y C NSAG S A + + + VT Sbjct: 358 LLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTG 417 Query: 930 --------FVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEG 979 ++H ++ G + IL CQ S T W + I D R I + Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSR--ISQH 475 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ 1024 D GV CI K+++ + T+ + Q Sbjct: 476 STGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQ 520 Score = 93.1 bits (221), Expect = 8e-17 Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 28/303 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F ++PK VD G+ +L +CR+ P+P I W K E +P +A ++ Sbjct: 227 PKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP-MPVTRAYIAKDN------R 279 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+I V+ EG Y A N G L+++ PP V G + Sbjct: 280 GLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQA----PPSFQTKPADQSVPAGGTAT 335 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPT--KSDG-----DTHSITILKPKKVKDEGVYTLK 806 +VG P P W K + P+ +DG T ++TI + ++V DEG Y Sbjct: 336 FECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQV-DEGAYVCA 394 Query: 807 AENSEG--IAETSAVITVEEPTEEN-AEPPLFINR-FQEITVKEKGTIKLVARVTRNPVP 862 NS G +++ + +T + T A+PP I Q T+ + L + + P P Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454 Query: 863 SITWYRNNEIISPSET-ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 I+W R+ I +++ I+Q+ G L I ++ + D+G Y C+A N G+S+ A + Sbjct: 455 GISWLRDGLPIDITDSRISQHSTG---SLHIADL-KKPDTGVYTCIAKNEDGESTWSASL 510 Query: 922 TID 924 T++ Sbjct: 511 TVE 513 Score = 93.1 bits (221), Expect = 8e-17 Identities = 66/207 (31%), Positives = 95/207 (45%), Gaps = 10/207 (4%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KP Q V G EC LV P P W +G++ + + A Sbjct: 316 PPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPT 375 Query: 693 SVLKITNVKKFQEGTYTVVAVNREG----EASLPIVLKIKTGE---KEPPQVIEPLKSMI 745 L I V++ EG Y +N G +A+L + K TG K PP + ++ Sbjct: 376 GTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQT 435 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYT 804 + G S IL Q G P P I+W ++ P+ ++ S T S+ I KK D GVYT Sbjct: 436 LMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKK-PDTGVYT 494 Query: 805 LKAENSEGIAETSAVITVEEPTEENAE 831 A+N +G + SA +TVE+ T NA+ Sbjct: 495 CIAKNEDGESTWSASLTVEDHT-SNAQ 520 Score = 78.6 bits (185), Expect = 2e-12 Identities = 126/603 (20%), Positives = 223/603 (36%), Gaps = 62/603 (10%) Query: 1203 PEFILVPANTDAYLTVEIPDETLDVTWYKK-KSVIEDTEKFT---LISDVKKRTLII--- 1255 P ++V + A L T +TWYK + VI + E+ ++ D L+ Sbjct: 37 PIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNS 96 Query: 1256 -RKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKR--GSDVTLLV--D 1310 + + D Y CV + K ++ D+ R + G ++ +L Sbjct: 97 GKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMAVLECSP 156 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGH-A 1369 + FP+P W + K ++ + ++ S +L I V+ +D+G Y+ N G Sbjct: 157 PRGFPEPVVSWRKDDKELRIQDMPRYTLHS-DGNLIIDPVDRSDSGTYQCVANNMVGERV 215 Query: 1370 DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 +++ +KP +P + +D + + +D I + + + + T Sbjct: 216 SNPARLSVFEKPKFEQEPKDMTVDVGAA-VLFDCRVTGDPQPQITWKRKNEPMPVTRAYI 274 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 K+ I+ ++ + + YA N +AS + +V Q+ ++ + Sbjct: 275 AKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASA---HLRVQAPPSFQTKPADQSVP 329 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK--LKTAKATYENRXXXXXXXXXXXXXX- 1546 T E C G P P W ++G++ L + + + R Sbjct: 330 AGGTATFE-----CTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVR 384 Query: 1547 -----XYKCIAFNDHG--------EVETSCVVG-IQQKPVITISNEDIKQKHKVGDEWLV 1592 Y C N G +V T V G KP TI + Q VG ++ Sbjct: 385 QVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAIL 444 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 G P P + W ++G L D + ++ T + I +LK+ + YT A N G Sbjct: 445 PCQASGKPTPGISWLRDG--LPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDG 502 Query: 1653 TSSVEVTLKVYDK---------------PSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 S+ +L V D PS P P+I+ ++ V + W P G Sbjct: 503 ESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIV-NVTDTEVELHWNAPSTSGAGP 561 Query: 1698 LTKYAIEKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 +T Y I+ + PD W + D E Y I+ L + YMF + A+N G S Sbjct: 562 ITGYIIQYYSPDLGQTWFNIPDYVASTE-YRIKGLKPSHSYMFVIRAENEKGIGTPSVSS 620 Query: 1757 PIV 1759 +V Sbjct: 621 ALV 623 Score = 72.5 bits (170), Expect = 1e-10 Identities = 135/617 (21%), Positives = 231/617 (37%), Gaps = 82/617 (13%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTAKATYENRXXXXXXXXXX 1542 +E P+ ++ L C G P K+TWY+DG+ + T K + Sbjct: 34 IEHPI-DVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90 Query: 1543 ------------XXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHK----V 1586 Y C+A N+HGEV+++ + + + ED + + + + Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSN-----EGSLKLAMLREDFRVRPRTVQAL 145 Query: 1587 GDEWLVTAVI--EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G E V G P P V W K+ +L T ++I I + RS S Y Sbjct: 146 GGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLI-IDPVDRSDSGTYQ 204 Query: 1645 IEASNTAGTS-SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 A+N G S L V++KP + P M +V + + D K Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWK--- 261 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA-----LESEPI 1758 K+EP +A +R + +Q +E EY+ A+NP G EA +++ P Sbjct: 262 RKNEPMPVTRAYIAKDNRGLRIERVQPSDEG-EYV--CYARNPAGTLEASAHLRVQAPPS 318 Query: 1759 VIKTALD--VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXX 1816 D VP+ + S W K G ++ + + +G+ K Sbjct: 319 FQTKPADQSVPAGGTATFECTLVGQPSPAYFW---SKEGQQDLL-FPSYVSADGRT-KVS 373 Query: 1817 XXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSE 1876 ++++ + N G+SL + T T P++P + Sbjct: 374 PTGTLTIEEVRQVDEGA---YVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHG 430 Query: 1877 STSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTK----IVTVGGSVHEHC-----I 1927 ++++ + G S I K G SW + I + +H I Sbjct: 431 HQNQTLMV--------GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHI 482 Query: 1928 ENIKEKDEIIFRISAENTVG-----VSLPTE-----SQSVRLEKHATVPSPPTAPLEIRM 1977 ++K+ D ++ A+N G SL E +Q VR+ + PS PT P+ + + Sbjct: 483 ADLKKPDTGVYTCIAKNEDGESTWSASLTVEDHTSNAQFVRMPDPSNFPSSPTQPIIVNV 542 Query: 1978 VGSNIVMTSWGTPEWDGGAPLLGYNIAIR--DVTKTMWMEVGKVDVNTLKFNIRDLSENH 2035 + + + W P G P+ GY I D+ +T W + +T ++ I+ L +H Sbjct: 543 TDTEVEL-HWNAPSTSGAGPITGYIIQYYSPDLGQT-WFNIPDYVAST-EYRIKGLKPSH 599 Query: 2036 TYMIRIYARNEIGLSEP 2052 +YM I A NE G+ P Sbjct: 600 SYMFVIRAENEKGIGTP 616 Score = 65.3 bits (152), Expect = 2e-08 Identities = 107/496 (21%), Positives = 183/496 (36%), Gaps = 43/496 (8%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI-----QFSNHIQLTIDGK 1159 L P II + V++G+ AT A + W+KDG + Q ++H + G Sbjct: 29 LAPVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGS 88 Query: 1160 KQKLKI---YDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTD--- 1213 LK+ + DAG Y C N + E S+ + +F + P Sbjct: 89 LFLLKVNSGKNGKDSDAGAYYCVASNEH--GEVKSNEGSLKLAMLREDFRVRPRTVQALG 146 Query: 1214 ---AYLTVEIPDETLD--VTWYK--KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 A L P + V+W K K+ I+D ++TL SD LII D Y Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD---GNLIIDPVDRSDSGTY 203 Query: 1267 TCV---LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIV 1323 CV ++ + + ++ V E PK ++ + G+ V PQP W Sbjct: 204 QCVANNMVGERVSNPARLSVFE-KPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITW-- 260 Query: 1324 NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSP 1383 + + T+ I + L I++V+ +D G Y N G + ++ + PS Sbjct: 261 -KRKNEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSF 319 Query: 1384 PGKPNILEIDSSSINICWDEPENTGNSTIIYYVVE--YQEIDTTEWISVKNITKTQ---- 1437 KP + + E G + Y+ + Q++ ++S TK Sbjct: 320 QTKPADQSVPAG--GTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGT 377 Query: 1438 TSIQNLKTNSSYRFRAYAVNEV--DISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTE 1494 +I+ ++ + +N +S A+ V T + PT+E +N T Sbjct: 378 LTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLM 437 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGK--KLKTAKATYENRXXXXXXXXXXXXXXXYKCIA 1552 L C G P P ++W RDG + ++ + + Y CIA Sbjct: 438 VGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIA 497 Query: 1553 FNDHGEVETSCVVGIQ 1568 N+ GE S + ++ Sbjct: 498 KNEDGESTWSASLTVE 513 Score = 64.5 bits (150), Expect = 3e-08 Identities = 84/350 (24%), Positives = 144/350 (41%), Gaps = 42/350 (12%) Query: 864 ITWYRNNE-IISPSETITQN---FDGENIELVITNVDS---EIDSGDYKCVASNSAG--K 914 ITWY++ + +I+ E + + D ++ L+ N + D+G Y CVASN G K Sbjct: 61 ITWYKDGQPVITNKEQVNSHRIVLDTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVK 120 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVS---TKWYHNKKE--ISG 969 S+ G+ + + + + F + ++ + G+ +LEC W + KE I Sbjct: 121 SNEGS-LKLAMLREDF-RVRPRTVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQD 178 Query: 970 MDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ-----ETSTMLVVKETIPEFIRKLQ 1024 M + +G D G +C+ + L V E P+F ++ + Sbjct: 179 MPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PKFEQEPK 234 Query: 1025 DFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHD 1083 D V + + + + + W+R E + + + RG L I D Sbjct: 235 DMTVDVGAAVLFDCRVTGDPQPQITWKRKNEPMPVTRAYIAKDNRG----LRIERVQPSD 290 Query: 1084 EGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRW 1139 EGEY C R+ + T E + V+ PP T+ +Q V G ATFE L + W Sbjct: 291 EGEYVCYARNPAGTLEASAHLRVQAPPSFQTKPADQSVPAGGTATFECTLVGQPSPAYFW 350 Query: 1140 FKDG-SEIQFSNHIQLTIDGKKQ-----KLKIYDCDLDDAGEYSCEVGNS 1183 K+G ++ F +++ + DG+ + L I + D G Y C NS Sbjct: 351 SKEGQQDLLFPSYV--SADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMNS 398 Score = 62.5 bits (145), Expect = 1e-07 Identities = 60/223 (26%), Positives = 84/223 (37%), Gaps = 30/223 (13%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR--QTAIIKPSQ-DFQMYYDDDNVA 566 P F K + P G T FEC + G P P W + Q ++ PS Sbjct: 317 PSFQTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTG 376 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXA 626 TL I EV D G + C N+AG + S L V Sbjct: 377 TLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKV-------------------TTKAVTG 417 Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI-VPDENISVAIE 685 + PPT + Q + GS +L C+ P P I+WL G I + D IS Sbjct: 418 NTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHST 477 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 +H I ++KK G YT +A N +GE++ L ++ Sbjct: 478 GSLH-------IADLKKPDTGVYTCIAKNEDGESTWSASLTVE 513 Score = 61.7 bits (143), Expect = 2e-07 Identities = 101/466 (21%), Positives = 181/466 (38%), Gaps = 60/466 (12%) Query: 1047 VVWERDGEIIKPKKN-KYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE-----SCTAEV 1100 V W +D + ++ + +Y G+ L I D G Y C+ + S A + Sbjct: 165 VSWRKDDKELRIQDMPRYTLHSDGN---LIIDPVDRSDSGTYQCVANNMVGERVSNPARL 221 Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDG 1158 +V E P+ ++ V+ G F+ +T GD + W + + + + I Sbjct: 222 SVFE-KPKFEQEPKDMTVDVGAAVLFDCRVT-GDPQPQITWKRKNEPMPVT---RAYIAK 276 Query: 1159 KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 + L+I D GEY C G + +A L V+ P +F + P VPA A Sbjct: 277 DNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPP-SFQTK-PADQSVPAGGTA 334 Query: 1215 YLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR-----TLIIRKCTEDDQCEYTCV 1269 + + ++ K+ + + +D + + TL I + + D+ Y C Sbjct: 335 TFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCA 394 Query: 1270 LLDA------KSTTKLKVEVV------EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQP 1317 +++ K+ K+ + V + PP I + + GS L P P Sbjct: 395 GMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMVGSSAILPCQASGKPTP 454 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSA-SLTIKKVENTDAGIYKLRLENNCGHADVEMNVT 1376 W+ + I T I S SL I ++ D G+Y +N G + ++T Sbjct: 455 GISWLRDGLPIDI---TDSRISQHSTGSLHIADLKKPDTGVYTCIAKNEDGESTWSASLT 511 Query: 1377 ILDK---------------PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 + D PS P +P I+ + + + + W+ P +G I Y+++Y Sbjct: 512 VEDHTSNAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYS 571 Query: 1422 IDTTE-WISVKN-ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 D + W ++ + + T+ I+ LK + SY F A NE I S Sbjct: 572 PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPS 617 Score = 61.7 bits (143), Expect = 2e-07 Identities = 47/135 (34%), Positives = 65/135 (48%), Gaps = 20/135 (14%) Query: 476 DENNYTQYLQKKLNEKID---KLPVFEKPTSEEQSMAPIFVEKLRPKH-TPD-GSTVQFE 530 D Y + E++ +L VFEKP E++ PK T D G+ V F+ Sbjct: 199 DSGTYQCVANNMVGERVSNPARLSVFEKPKFEQE-----------PKDMTVDVGAAVLFD 247 Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+V G P+PQITW R+ +P + Y DN L I V P D G + C A+N AG Sbjct: 248 CRVTGDPQPQITWKRKN---EPMPVTRAYIAKDN-RGLRIERVQPSDEGEYVCYARNPAG 303 Query: 591 FASSTTELIVEAPLS 605 ++ L V+AP S Sbjct: 304 TLEASAHLRVQAPPS 318 Score = 56.4 bits (130), Expect = 8e-06 Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 2/93 (2%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK-GKSWTKIVTVGGSVHE 1924 PS P ++ T V L W P ++G PIT YII++ + G++W I S E Sbjct: 531 PSSPTQPIIVNVTDTEVELHWNAPSTSGAGPITGYIIQYYSPDLGQTWFNIPDYVAST-E 589 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 + I+ +K +F I AEN G+ P+ S ++ Sbjct: 590 YRIKGLKPSHSYMFVIRAENEKGIGTPSVSSAL 622 Score = 54.8 bits (126), Expect = 2e-05 Identities = 84/403 (20%), Positives = 142/403 (35%), Gaps = 42/403 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEK----RGHIR 1072 P I D V A L TA + W +DG+ + K + + + G + Sbjct: 31 PVIIEHPIDVVVSRGSPATLNCGAKPSTAKITWYKDGQPVITNKEQVNSHRIVLDTGSLF 90 Query: 1073 KLYI---RNTSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124 L + +N D G Y C+ +E S + + L + R + + G A Sbjct: 91 LLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQALGGEMA 150 Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 E +G + +V W KD E++ + + T+ L I D D+G Y C N Sbjct: 151 VLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLH-SDGNLIIDPVDRSDSGTYQCVANN 209 Query: 1183 ------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSV 1235 S + E+P + P+ + V + D +TW +K Sbjct: 210 MVGERVSNPARLSVFEKPKFE---QEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRKNEP 266 Query: 1236 IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYE 1294 + T + + D R L I + D+ EY C + T + + V+ PP Sbjct: 267 MPVTRAY-IAKD--NRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTKP 323 Query: 1295 REYRIKRGSDVTLLVDYQAFPQPNDEW-------IVNSKIIKKCKHTKPSIDSKSASLTI 1347 + + G T P P W ++ + TK S + +LTI Sbjct: 324 ADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKV---SPTGTLTI 380 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKP 1387 ++V D G Y N+ G + + + + K + P KP Sbjct: 381 EEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKP 423 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Query: 524 GSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMY--YDDDNVATLVIREVFPEDAGT 580 G EC G+P P ++W + ++ QD Y + D N L+I V D+GT Sbjct: 147 GEMAVLECSPPRGFPEPVVSWRKDDKELR-IQDMPRYTLHSDGN---LIIDPVDRSDSGT 202 Query: 581 FTCVAKNAAG 590 + CVA N G Sbjct: 203 YQCVANNMVG 212 >UniRef50_Q9UQ52 Cluster: Contactin-6 precursor; n=78; Euteleostomi|Rep: Contactin-6 precursor - Homo sapiens (Human) Length = 1028 Score = 99.5 bits (237), Expect = 9e-19 Identities = 188/929 (20%), Positives = 333/929 (35%), Gaps = 68/929 (7%) Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI- 1196 RW ++G++I F+ +DG + D D G Y C N T + + Sbjct: 61 RWKQNGTDIDFTMSYHYRLDGGSLAINSPHTD-QDIGMYQCLATNLLGTILSRKAKLQFA 119 Query: 1197 ---NFTLRLPEFILVPANTDAYLTVEIPDETLDVT--WYKKKSVIEDTEKFTLISDVKKR 1251 +F + + V L P D++ W + + E + Sbjct: 120 YIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETG 179 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTTKLK------VE-----VVEFPPKI-VDYEREYRI 1299 L I K D YTC + + ++ ++ V+ + E+ PKI V + + Sbjct: 180 NLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQA 239 Query: 1300 KRGSDVTLLVDYQAFPQPNDEW--IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 + S V L P P+ W + S + K K++K A L I + D G Sbjct: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSK-----SQAILEIPNFQQEDEGF 294 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY-YV 1416 Y+ N G + + P K + S N+ W E + +G Y ++ Sbjct: 295 YECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHL-SIYDNLLW-ECKASGKPNPWYTWL 352 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + ++ E I ++N T T L + S ++ A N+ I A+ + Sbjct: 353 KNGERLNPEERIQIENGTLIITM---LNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXX 1535 +SP +K + DI + C P+ ++W R + L+ +K + Sbjct: 410 FS-KSPVKKKSFVQV----GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSL 464 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y CIA N G + + + ++++ VIT+ K VG+ ++ Sbjct: 465 KIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPS--KMDVTVGESIVLPCQ 522 Query: 1596 IEGIPPPEVI--WYKNGNKLENDK---EYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + P EV+ W+ NG+ ++ K + E + I+ ++ HS KY T Sbjct: 523 VSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTT 582 Query: 1651 AGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN 1710 + S + V P PE V + +IS + + W+ D+ + + I+ P + Sbjct: 583 LESLSAVADIIVRGPPGPPED-VQVEDISSTTSQLSWRAGPDNNS-PIQIFTIQTRTPFS 640 Query: 1711 NRWIKVADVDRDV--ETY--CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDV 1766 W VA V + +TY + L+ EY FRV+A N +G E E + ++T V Sbjct: 641 VGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSEL-LRTKASV 699 Query: 1767 PSXXXXXXXXXXIDNESVYITW--FPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXX 1823 P + ITW P E G Y + + G W Sbjct: 700 PVVAPVNIHGGGGSRSELVITWESIPEELQNGEG-FGYIIMFRPVGSTTWSKEKVSSVES 758 Query: 1824 ARI----QKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTS 1879 +R + + + ++ ++ N G S I P PR + ++ Sbjct: 759 SRFVYRNESIIPLSPFEVKVGVYNNEGEG--SLSTVTIVYSGEDEPQLAPRGTSLQSFSA 816 Query: 1880 RSVTLKWTEPESNGGS-PITNYIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEII 1937 + + W N + + Y + + T K S + V G+V I +K Sbjct: 817 SEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNITGLKANTIYF 876 Query: 1938 FRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAP 1997 + A NT G S V + + PS P A + ++ S + + + + Sbjct: 877 ASVRAYNTAGTG--PSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESE 934 Query: 1998 LLGYNIAIRD--VTKTMWMEVGKVDVNTL 2024 +LGY I R +KT +E L Sbjct: 935 VLGYKILYRQNRQSKTHILETNNTSAELL 963 Score = 85.4 bits (202), Expect = 2e-14 Identities = 79/328 (24%), Positives = 142/328 (43%), Gaps = 27/328 (8%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ + S + LEC + P PDI+W +P + V ++L+I N Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGK---VKYSKSQ----AILEIPN 286 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 ++ EG Y +A N G + K + PP+ + +++ + ++++ + Sbjct: 287 FQQEDEGFYECIASNLRGRN----LAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKAS 342 Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 G P P TW KN + + P + + I+ V D GVY AEN I +A Sbjct: 343 GKPNPWYTWLKNGERLN--PEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAE 400 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 + V + ++ P+ F V+ G I + + P +I+W R E + S+ I Sbjct: 401 LRVLASAPDFSKSPVKKKSF----VQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRI 456 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 DG L I N+ + D+G Y C+A+N G + + ++ V++ T + + Sbjct: 457 FLLEDG---SLKIYNI-TRSDAGSYTCIATNQFGTAKNTG--SLIVKERTVITVPPSKMD 510 Query: 940 TEEGKTVILECQTSHTVSTK----WYHN 963 G++++L CQ SH S + W+ N Sbjct: 511 VTVGESIVLPCQVSHDPSIEVVFVWFFN 538 Score = 66.1 bits (154), Expect = 1e-08 Identities = 68/302 (22%), Positives = 128/302 (42%), Gaps = 35/302 (11%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP + +K + ++ ++L EC+ P P WL GE + P+E I + + + Sbjct: 317 PPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI---ENGTLII 373 Query: 693 SVLKITNVKKFQ---EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 ++L +++ +Q E Y ++ N A L ++ K P + K V+ G Sbjct: 374 TMLNVSDSGVYQCAAENKYQIIYAN----AELRVLASAPDFSKSPVK-----KKSFVQVG 424 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 +++ + PR I+W + + + K + DG I + D G YT Sbjct: 425 GDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITR----SDAGSYTCI 480 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI-- 864 A N G A+ + + V+E T P ++TV E +I L +V+ +P + Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSK-----MDVTVGE--SIVLPCQVSHDPSIEVVF 533 Query: 865 TWYRNNEIISPSETIT--QNFDGENI-ELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 W+ N ++I + + + GE++ +L+I N+ SG Y C + S A + Sbjct: 534 VWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLH-HSGKYLCTVQTTLESLSAVADI 592 Query: 922 TI 923 + Sbjct: 593 IV 594 Score = 59.7 bits (138), Expect = 9e-07 Identities = 125/560 (22%), Positives = 213/560 (38%), Gaps = 52/560 (9%) Query: 649 SDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE-GT 707 S+++L C P P W G +I D +S D L I + Q+ G Sbjct: 44 SEVILNCAANGYPSPHYRWKQNGTDI--DFTMSYHYRLDG----GSLAINSPHTDQDIGM 97 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP--- 764 Y +A N G L K++ E + + ++ VR+G+ V+L + G P Sbjct: 98 YQCLATNLLGTI-LSRKAKLQFAYIEDFET-KTRSTVSVREGQGVVL---LCGPPPHFGD 152 Query: 765 -TITWCKNNKPVKALPTKS---DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVI 820 + W N+ P+ +T ++ I K + D G YT N E Sbjct: 153 LSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEP-SDVGNYTCFITNKEAQRSVQGPP 211 Query: 821 T-VEEPTEE---NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 T + + T+ EP + + + I + ++KL NPVP I+W R + P Sbjct: 212 TPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPG 271 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + + L I N E D G Y+C+ASN G++ ++ I + + +Q Sbjct: 272 KV---KYSKSQAILEIPNFQQE-DEGFYECIASNLRGRNLAKGQL-IFYAPPEWEQKIQN 326 Query: 937 SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 ++ ++ EC+ S WY K ++ E IQ D GV Sbjct: 327 TH-LSIYDNLLWECKASGK-PNPWYTWLKNGERLNPEERIQI-ENGTLIITMLNVSDSGV 383 Query: 997 IKCIVKDQ----ETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEINSETADVVW 1049 +C +++ + L V + P+F + K + F D+ I A + W Sbjct: 384 YQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW 443 Query: 1050 ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELP 1106 +R E ++ K + E G + K+Y N + D G Y+CI ++ TA+ T +V+ Sbjct: 444 KRGTETLRQSKRIFLLED-GSL-KIY--NITRSDAGSYTCIATNQFGTAKNTGSLIVKER 499 Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEIQFSN---HIQLTIDGKK 1160 I V G +++ + + WF +G I H + Sbjct: 500 TVITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESV 559 Query: 1161 QKLKIYDCDLDDAGEYSCEV 1180 L I + L +G+Y C V Sbjct: 560 GDLMIRNIQLHHSGKYLCTV 579 Score = 58.4 bits (135), Expect = 2e-06 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 11/175 (6%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV----GG 1920 PP P + V + +S + L W N SPI + I+ +T W + TV G Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNN-SPIQIFTIQTRTPFSVGWQAVATVPEILNG 655 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG- 1979 + + + E FR+ A N++G+ P+E + L A+VP AP+ I G Sbjct: 656 KTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSEL-LRTKASVPV--VAPVNIHGGGG 712 Query: 1980 --SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLS 2032 S +V+T PE GY I R V T W + V + +F R+ S Sbjct: 713 SRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFVYRNES 767 Score = 47.2 bits (107), Expect = 0.005 Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + C+ +PR I+W R T ++ S+ + D +L I + DAG++TC Sbjct: 424 GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLED----GSLKIYNITRSDAGSYTC 479 Query: 584 VAKNAAGFASSTTELIVE 601 +A N G A +T LIV+ Sbjct: 480 IATNQFGTAKNTGSLIVK 497 Score = 45.6 bits (103), Expect = 0.015 Identities = 131/620 (21%), Positives = 230/620 (37%), Gaps = 57/620 (9%) Query: 732 KEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK-ALPTKSDGDTHSIT 790 +EP VI PL + + E VIL+ G P P W +N + + D S+ Sbjct: 30 QEPHDVIFPLD---LSKSE-VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE-KGT 849 I P +D G+Y A N G S ++ E+ E ++V+E +G Sbjct: 86 INSPHTDQDIGMYQCLATNLLGTI-LSRKAKLQFAYIEDFET----KTRSTVSVREGQGV 140 Query: 850 IKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS 909 + L S W N+ + E + E L I V+ D G+Y C + Sbjct: 141 VLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPS-DVGNYTCFIT 199 Query: 910 NSAGKSSHGARVTIDVEKVTFVK---------HLQKSYETEEGKTVILECQTSHTVSTKW 960 N + S T V++ V ++ + + +V LEC Sbjct: 200 NKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDI 259 Query: 961 YHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIP 1017 + + S + + + + D G +CI + + ++ P Sbjct: 260 SWRRLDGSPLPGKVKYSKSQAILEIPNFQQE-DEGFYECIASNLRGRNLAKGQLIFYAPP 318 Query: 1018 EFIRKLQDFEVKEKDVAILEVEINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYI 1076 E+ +K+Q+ + D + E + + + W ++GE + P++ + E L I Sbjct: 319 EWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEE-RIQIENG----TLII 373 Query: 1077 RNTSVHDEGEYSCILRDES----CTAEVTVVELPPEIITRLQNQK--VNKGNKATFEIEL 1130 +V D G Y C ++ AE+ V+ P+ +K V G + Sbjct: 374 TMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKP 433 Query: 1131 TKGD-ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKC 1185 A + W + ++ S I L DG LKIY+ DAG Y+C + G +K Sbjct: 434 NAFPRAAISWKRGTETLRQSKRIFLLEDGS---LKIYNITRSDAGSYTCIATNQFGTAKN 490 Query: 1186 TAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETLDV--TWYKKKSVIE---DT 1239 T L V+E ++ T+ P + V L ++ D +++V W+ VI+ Sbjct: 491 TGSLIVKERTV-ITVP-PSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGV 548 Query: 1240 EKFTLISDVKKRTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEFPPKIVDYEREYR 1298 F I L+IR +Y C V +S + + +V PP + + Sbjct: 549 AHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPP---GPPEDVQ 605 Query: 1299 IKRGSDVTLLVDYQAFPQPN 1318 ++ S T + ++A P N Sbjct: 606 VEDISSTTSQLSWRAGPDNN 625 Score = 43.6 bits (98), Expect = 0.061 Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 5/97 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P + +K++ H + +EC+ G P P TW + + P + Q+ +N TL+ Sbjct: 318 PEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQI----EN-GTLI 372 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSD 606 I + D+G + C A+N + EL V A D Sbjct: 373 ITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPD 409 Score = 36.7 bits (81), Expect = 7.0 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 4/79 (5%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S+V+ EC G P P I+W R P + + Y A L I ED G + C+ Sbjct: 243 SSVKLECFALGNPVPDISWRRLDGSPLPGK---VKYSKSQ-AILEIPNFQQEDEGFYECI 298 Query: 585 AKNAAGFASSTTELIVEAP 603 A N G + +LI AP Sbjct: 299 ASNLRGRNLAKGQLIFYAP 317 >UniRef50_Q59FX6 Cluster: Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant; n=14; Amniota|Rep: Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant - Homo sapiens (Human) Length = 1560 Score = 99.1 bits (236), Expect = 1e-18 Identities = 108/530 (20%), Positives = 198/530 (37%), Gaps = 37/530 (6%) Query: 1473 VIKETKIQS--PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRD----GKKLKTAK 1526 V++E ++ S P ++ + E + C G P P++TW++D + Sbjct: 150 VLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGR 209 Query: 1527 ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKV 1586 Y+C+A N G +S + + + H++ Sbjct: 210 IKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEI 269 Query: 1587 --GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 G +T V G P P V W + L + + + +V+ + ++K S+ YT Sbjct: 270 MPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDDMPV----GRNVLELTDVK--DSANYT 323 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 A ++ G + V P P P++ E + S+TI W D G + Y + Sbjct: 324 CVAMSSLGVIEAVAQITVKSLPKAPGTPMV-TENTATSITITW----DSGNPDPVSYYVI 378 Query: 1705 KHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTAL 1764 +++ + D Y I L+ N EY V A N +G + SE +V +T Sbjct: 379 EYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG--QGPPSESVVTRTGE 436 Query: 1765 DVPSXXXXXXXXXXIDNESVYITW-FPSEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXX 1821 P+ + ++ + W P E NG + Y +E + W+ Sbjct: 437 QAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDS 496 Query: 1822 XXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + L + TY R+ A +G P + D I + P QP N + S Sbjct: 497 LLTTVGSLLEDETYTVRVLAFTSVGDG-PLS--DPIQVKTQQGVPGQPMNLRAEARSETS 553 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 +TL W+ P I Y + F+ +G ++ + +E++K E FR++ Sbjct: 554 ITLSWSPPRQES---IIKYELLFR--EGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLA 608 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 A + G+ T + + T+ S +++M+ V+ SW P+ Sbjct: 609 ARSPQGLGAFTP-----VVRQRTLQSISPKNFKVKMIMKTSVLLSWEFPD 653 Score = 88.6 bits (210), Expect = 2e-15 Identities = 144/659 (21%), Positives = 253/659 (38%), Gaps = 58/659 (8%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSA 1343 E PP+ + ++ G + + P+P W K + + D S A Sbjct: 56 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGA 115 Query: 1344 SLTIKKVENT-DAGIYKLRLENNCGHADVEMNVTILDKPS-PPGKPNI--------LEID 1393 L I+ + D +Y+ +N+ G V +T+L + P G PNI +E Sbjct: 116 VLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERT 175 Query: 1394 SSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRF 1451 ++ +C +GN I + ++ +D + +K + I++ + ++ Sbjct: 176 RTATMLC----AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKY 231 Query: 1452 RAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQP 1511 A N + +S Y +V ++ P+ + P ++ +TC+ G P P Sbjct: 232 ECVATNSAGVRYSSPANLYVRV---RRVAPRFSILPMSH-EIMPGGNVNITCVAVGSPMP 287 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 V W + + L R Y C+A + G +E + ++ P Sbjct: 288 YVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSAN--YTCVAMSSLGVIEAVAQITVKSLP 345 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKEYNITTKEKTSVI 1630 + + +T + P V +Y K ++ D Y I T+ Sbjct: 346 KAP-GTPMVTENTATS----ITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRY 400 Query: 1631 RIKELKRSHSSKYTIEASNTAGT---SSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 I L + + + A N+ G S VT P+ V R +S ++ ++W Sbjct: 401 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 460 Query: 1688 KPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + P++ GL Y +E P N W K +VD + T + L E+ Y RV+A Sbjct: 461 EEPVEPNGLIRGYRVYYTMEPEHPVGN-WQK-HNVDDSLLT-TVGSLLEDETYTVRVLAF 517 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 VG + S+PI +KT VP + S+ ++W P + II Y++ Sbjct: 518 TSVG--DGPLSDPIQVKTQQGVPGQPMNLRAEARSET-SITLSWSPPRQES---IIKYEL 571 Query: 1805 EIKQEGKKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 + +EG + ++ L NT Y FR+ AR+ G +T + +T Sbjct: 572 -LFREGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGA-FTP---VVRQRT 626 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK----TVKGKSWTKIVT 1917 L S P+NF V SV L W P+ N SP T Y I++ V G++ K++T Sbjct: 627 LQSIS-PKNFKVKMIMKTSVLLSWEFPD-NYNSP-TPYKIQYNGLTLDVDGRTTKKLIT 682 Score = 82.6 bits (195), Expect = 1e-13 Identities = 72/264 (27%), Positives = 117/264 (44%), Gaps = 10/264 (3%) Query: 717 GEASLPIVLKIK-TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV 775 G L +VL + +EPP+ I+ K I G Q G+P+P +TW K K V Sbjct: 40 GPMGLLVVLLVGGCAAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV 99 Query: 776 KALPTKS---DGDTHSITILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + ++ D ++ ++P + +DE VY A+NS G A +TV + + Sbjct: 100 NSQRFETIEFDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 159 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P Q V+ T ++ + NP P ITW+++ + PS + + + L Sbjct: 160 FPNIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQ 219 Query: 892 ITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDVEKVT-FVKHLQKSYETEEGKTVILE 949 I + E D G Y+CVA+NSAG + S A + + V +V L S+E G V + Sbjct: 220 IES-SEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNIT 278 Query: 950 CQT--SHTVSTKWYHNKKEISGMD 971 C S KW ++++ D Sbjct: 279 CVAVGSPMPYVKWMQGAEDLTPED 302 Score = 81.8 bits (193), Expect = 2e-13 Identities = 82/337 (24%), Positives = 140/337 (41%), Gaps = 34/337 (10%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ + + G F CQ G P+P++TW ++ + + + +D+ A L Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118 Query: 570 IREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADI 628 I+ + P D + CVA+N+ G E+ V A L+ D Sbjct: 119 IQPLRTPRDENVYECVAQNSVG------EITVHAKLT-----------------VLREDQ 155 Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 L P P+ + V+ + C P+P+I W FK + +P + S + Sbjct: 156 LPSGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITW-FK--DFLPVDP-SASNGRIK 211 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + L+I + ++ +G Y VA N G S P L ++ P I P+ I+ Sbjct: 212 QLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM- 270 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 G +V ++ VG+P P + W + + + T D +L+ VKD YT A Sbjct: 271 PGGNVNITCVAVGSPMPYVKWMQGAEDL----TPEDDMPVGRNVLELTDVKDSANYTCVA 326 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 +S G+ E A ITV+ + P + N IT+ Sbjct: 327 MSSLGVIEAVAQITVKSLPKAPGTPMVTENTATSITI 363 Score = 80.2 bits (189), Expect = 6e-13 Identities = 75/299 (25%), Positives = 127/299 (42%), Gaps = 23/299 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F K+PK Q G C+ P+P + W KG+++ + IE D Sbjct: 58 PPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKV--NSQRFETIEFD-ESAG 114 Query: 693 SVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP---PQVIEPLKSMIVRQ 748 +VL+I ++ E Y VA N GE ++ L + ++ P P + + +V + Sbjct: 115 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 174 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYT 804 + + GNP P ITW K+ PV P+ S+G + ++ + D+G Y Sbjct: 175 TRTATMLCAASGNPDPEITWFKDFLPVD--PSASNGRIKQLRSGALQIESSEETDQGKYE 232 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A NS G+ +S P F + G + + +P+P + Sbjct: 233 CVATNSAGVRYSSPANLY---VRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 289 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + E ++P + + G N+ L +T+V DS +Y CVA +S G A++T+ Sbjct: 290 KWMQGAEDLTPEDDMPV---GRNV-LELTDVK---DSANYTCVAMSSLGVIEAVAQITV 341 Score = 79.4 bits (187), Expect = 1e-12 Identities = 92/385 (23%), Positives = 148/385 (38%), Gaps = 32/385 (8%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFSNHIQLTIDGKKQ 1161 E PP I ++Q G A+F + T GD R W K G ++ + D Sbjct: 56 EEPPRFIKEPKDQIGVSGGVASFVCQAT-GDPKPRVTWNKKGKKVNSQRFETIEFDESAG 114 Query: 1162 K-LKIYDCDLD-DAGEYSCEVGNS--------KCTAILTVEEPSINFTLRL-PEFILVP- 1209 L+I D Y C NS K T + + PS + + P+ +V Sbjct: 115 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 174 Query: 1210 ANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 T L + ++TW+K ++ + I ++ L I E DQ +Y CV Sbjct: 175 TRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECV 234 Query: 1270 LLDA-----KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 ++ S L V V P+ + I G +V + P P +W+ Sbjct: 235 ATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQG 294 Query: 1325 SKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 ++ + P D ++ + D+ Y ++ G + +T+ P P Sbjct: 295 AEDLT------PEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAP 348 Query: 1385 GKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWISVK-NITKTQTSIQN 1442 G P + E ++SI I WD +GN + YYV+EY+ +K +IT T+ SI Sbjct: 349 GTPMVTENTATSITITWD----SGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGG 404 Query: 1443 LKTNSSYRFRAYAVNEVDISDASET 1467 L NS Y AVN + SE+ Sbjct: 405 LSPNSEYEIWVSAVNSIGQGPPSES 429 Score = 63.7 bits (148), Expect = 5e-08 Identities = 51/218 (23%), Positives = 101/218 (46%), Gaps = 12/218 (5%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P +V+E+T+ S+T+ W +S P++ Y+IE+K+ K + + + + Sbjct: 345 PKAPGTPMVTENTATSITITW---DSGNPDPVSYYVIEYKS-KSQDGPYQIKEDITTTRY 400 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 I + E +SA N++G P+ES R + A +P ++ RM+ + ++ Sbjct: 401 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRN--VQARMLSATTMIV 458 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN-TLKFNIRDLSENHTYMIRIYAR 2044 W P G + GY + + K +V+ +L + L E+ TY +R+ A Sbjct: 459 QWEEPVEPNGL-IRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAF 517 Query: 2045 NEIG---LSEPLESDEPFKVIPGEGSHADEEPGEQTEV 2079 +G LS+P++ + + +PG+ + E +T + Sbjct: 518 TSVGDGPLSDPIQV-KTQQGVPGQPMNLRAEARSETSI 554 >UniRef50_P16621 Cluster: Tyrosine-protein phosphatase Lar precursor; n=37; cellular organisms|Rep: Tyrosine-protein phosphatase Lar precursor - Drosophila melanogaster (Fruit fly) Length = 2029 Score = 99.1 bits (236), Expect = 1e-18 Identities = 128/610 (20%), Positives = 234/610 (38%), Gaps = 38/610 (6%) Query: 1451 FRAYAVNEV-DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 + A N V D A T Y+ K T P + + E + +TC G P Sbjct: 109 YECVAENGVGDAVSADATLTIYEGDK-TPAGFPVITQGPGTRVIEVGHTVLMTCKAIGNP 167 Query: 1510 QPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX-YKCIAFNDHGEVE---TSCVV 1565 P + W ++ K+ + Y + Y+C+A N G T+ V Sbjct: 168 TPNIYWIKNQTKVDMSNPRYSLKDGFLQIENSREEDQGKYECVAENSMGTEHSKATNLYV 227 Query: 1566 GIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKE 1625 +++ P + + +G ++ + G P P V W K L + E I + Sbjct: 228 KVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKWMKGSEDLTPENEMPIG-RN 286 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 +I I+E S+ YT A++T G +KV P+ P V + E++ SV + Sbjct: 287 VLQLINIQE-----SANYTCIAASTLGQIDSVSVVKVQSLPTAPTD-VQISEVTATSVRL 340 Query: 1686 EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY-CIQKLNENCEYMFRVIAQ 1744 EW G E +Y + +++P N +++ + Y ++ L+ EY F VIA Sbjct: 341 EWSYK----GPEDLQYYVIQYKPKNANQA-FSEISGIITMYYVVRALSPYTEYEFYVIAV 395 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKV 1804 N +G S P T + + ++ ITW P E G + YKV Sbjct: 396 NNIG--RGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMVITWEPPETPNGQ-VTGYKV 452 Query: 1805 ----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIG 1860 Q W + +L+ + Y R+ A +G P ++ ++ Sbjct: 453 YYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAG-PMSTPVQVKAQ 511 Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-TVKGKSWTKIVTVG 1919 + + PSQP NF ++ +VTL+WT+P ++ I +Y + + T ++ K ++ Sbjct: 512 QGV--PSQPSNFRATDIGETAVTLQWTKP-THSSENIVHYELYWNDTYANQAHHKRIS-- 566 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 + + ++ + ++A + G T VR +++ VP P + Sbjct: 567 -NSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQY--VPGAPPRNITAIATS 623 Query: 1980 SNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYM 2038 S + SW P + ++ Y + +V + E + +N + +L Y Sbjct: 624 STTISLSWLPPPVERSNGRIIYYKVFFVEVGRED-DEATTMTLNMTSIVLDELKRWTEYK 682 Query: 2039 IRIYARNEIG 2048 I + A +G Sbjct: 683 IWVLAGTSVG 692 Score = 88.2 bits (209), Expect = 2e-15 Identities = 74/289 (25%), Positives = 131/289 (45%), Gaps = 21/289 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP +KP+ Q V G C P P I W G+++ ++ +E + Sbjct: 35 PPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGI-- 92 Query: 693 SVLKITNVKKFQEGT-YTVVAVNREGEA-SLPIVLKIKTGEKEP---PQVIEPLKSMIVR 747 S+L+I V+ ++ Y VA N G+A S L I G+K P P + + + ++ Sbjct: 93 SILRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIE 152 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 G +V+++ + +GNP P I W KN V + P S D ++ + +D+G Y Sbjct: 153 VGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKD--GFLQIENSREEDQGKYECV 210 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT-IKLVARVTRNPVPSIT 865 AENS G + A + PP F + I+ G+ + L +P+P + Sbjct: 211 AENSMGTEHSKATNLY---VKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVK 267 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 W + +E ++P + G N+ L + N+ +S +Y C+A+++ G+ Sbjct: 268 WMKGSEDLTPENEMP---IGRNV-LQLINIQ---ESANYTCIAASTLGQ 309 Score = 83.4 bits (197), Expect = 6e-14 Identities = 197/995 (19%), Positives = 370/995 (37%), Gaps = 91/995 (9%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEIQF--SNHIQLTIDGKKQ 1161 PPEII + QNQ V G A+F +GD + W K+G ++ S + L G Sbjct: 35 PPEIIRKPQNQGVRVGGVASFYCA-ARGDPPPSIVWRKNGKKVSGTQSRYTVLEQPGGIS 93 Query: 1162 KLKIYD--CDLDDAGEYSCEVGNS-----KCTAILTVEEPS---INFTL--RLPEFILVP 1209 L+I DDA Y C N A LT+ E F + + P ++ Sbjct: 94 ILRIEPVRAGRDDA-PYECVAENGVGDAVSADATLTIYEGDKTPAGFPVITQGPGTRVIE 152 Query: 1210 ANTDAYLTVE-IPDETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 +T + I + T ++ W K ++ ++ +++L K L I E+DQ +Y Sbjct: 153 VGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSL----KDGFLQIENSREEDQGKYE 208 Query: 1268 CVLLDAKST-----TKLKVEVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 CV ++ T T L V+V PP E + GS++ L P P+ +W Sbjct: 209 CVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLSCIAVGSPMPHVKW 268 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + S+ + P + ++ + ++ Y + G D V + P Sbjct: 269 MKGSEDL------TPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKVQSLP 322 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSI 1440 + P I E+ ++S+ + W G + YYV++Y+ + + S + I + Sbjct: 323 TAPTDVQISEVTATSVRLEW---SYKGPEDLQYYVIQYKPKNANQAFSEISGIITMYYVV 379 Query: 1441 QNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIE 1500 + L + Y F AVN + S ETK++S ++ ++ + + Sbjct: 380 RALSPYTEYEFYVIAVNNIGRGPPSAPATC--TTGETKMESAPRNVQVRTLS---SSTMV 434 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 +T P +VT Y+ + + + + Sbjct: 435 ITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAY 494 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 TS G PV + + + + + T + G + W K + EN Y Sbjct: 495 TSMGAGPMSTPVQVKAQQGVPSQ---PSNFRATDI--GETAVTLQWTKPTHSSENIVHYE 549 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIE-------------ASNTAGTSSVEVTLKVYDKPS 1667 + + T + + S+S YT++ A + G + + V K Sbjct: 550 LYWND-TYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQY 608 Query: 1668 KPEGP---VIMREISRESVTIEW-KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDV 1723 P P + S ++++ W PP++ + Y + E + + ++ Sbjct: 609 VPGAPPRNITAIATSSTTISLSWLPPPVERSNGRIIYYKVFFVEVGRED-DEATTMTLNM 667 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 + + +L EY V+A VG + S PI+++T DVP +++ S Sbjct: 668 TSIVLDELKRWTEYKIWVLAGTSVG--DGPRSHPIILRTQEDVPG-DPQDVKATPLNSTS 724 Query: 1784 VYITWFPS-EKNGGSPIIDYKV---EIKQEGKKWK----XXXXXXXXXARIQKLSINTTY 1835 ++++W P EK+ I Y + E++ EGK + + L +T Y Sbjct: 725 IHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKY 784 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGS 1895 ++ A G + T G P+ + E S+ L+W P G Sbjct: 785 SIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPIV-SIELEWERPAQTYGE 843 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 + Y + + VK ++ + + G + + +N++ E FR++ N +G+ E+ Sbjct: 844 -LRGYRLRW-GVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIG--QETV 899 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD-GGAPLLGYNIAIRDVTKTMWM 2014 + T P P + + IR +++ +W P + + Y++ K + Sbjct: 900 KIFQTPEGT-PGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFH---KKIDH 955 Query: 2015 EVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIG 2048 +G TL K +L EN Y+ R+ A + G Sbjct: 956 GLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQG 990 Score = 57.2 bits (132), Expect = 5e-06 Identities = 108/453 (23%), Positives = 169/453 (37%), Gaps = 40/453 (8%) Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVY-DKPSKPEGP 1672 D E T TS++ + ELKR K + A + G S + L+ D P P+ Sbjct: 657 DDEATTMTLNMTSIV-LDELKRWTEYKIWVLAGTSVGDGPRSHPIILRTQEDVPGDPQD- 714 Query: 1673 VIMREISRESVTIEWKPPLD-DGGLELTKYAIEKHE-PDNNRWIKVADVDRD-VET--YC 1727 V ++ S+ + WKPPL+ D + Y I E D + D V+T + Sbjct: 715 VKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFN 774 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN-ESVYI 1786 + L + +Y +V A G + S IV+KT VP + S+ + Sbjct: 775 VTGLQPDTKYSIQVAALTRKGDGD--RSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIEL 832 Query: 1787 TW-FPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845 W P++ G + +K + K + R L Y+FR+ N I Sbjct: 833 EWERPAQTYGELRGYRLRWGVKDQALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHI 892 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEF 1904 G KI TP P N + T + + W P + IT Y ++F Sbjct: 893 GIG---QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQF 949 Query: 1905 --KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 K G + +T+ +V N++E E IFR+ A G ++ V E+ Sbjct: 950 HKKIDHGLGSERNMTLRKAV----FTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETER- 1004 Query: 1963 ATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNI-----AIRDVTKTMWMEV 2016 AP+ ++ S W P G LLGY I A+ D+ V Sbjct: 1005 ----DMGRAPMSLQAEATSEQTAEIWWEPVTSRG-KLLGYKIFYTMTAVEDLDDWQTKTV 1059 Query: 2017 GKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 G + L N+ ++ Y + I AR + GL Sbjct: 1060 GLTESADL-VNLEKFAQ---YAVAIAARFKNGL 1088 Score = 56.0 bits (129), Expect = 1e-05 Identities = 83/359 (23%), Positives = 143/359 (39%), Gaps = 39/359 (10%) Query: 1631 RIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGP---VIMREISRESVTIE 1686 R L+R ++ + SN G + T+K++ P P GP + +R + + + + Sbjct: 872 RFDNLERGVEYEFRVAGSNHIGIG--QETVKIFQTPEGTPGGPPSNITIRFQTPDVLCVT 929 Query: 1687 WKPPLDD--GGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 W PP + G+ +T+Y ++ H+ ++ ++ + + L EN EY+FRV A Sbjct: 930 WDPPTREHRNGI-ITRYDVQFHKKIDHGL--GSERNMTLRKAVFTNLEENTEYIFRVRAY 986 Query: 1745 NPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG---GSPIID 1801 G S+ ++++T D+ ++ I W P G G I Sbjct: 987 TKQGAGPF--SDKLIVETERDM-GRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIF- 1042 Query: 1802 YKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGK 1861 Y + ++ W+ A + L Y I AR + G +K+T+ Sbjct: 1043 YTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLG---RLSEKVTV-- 1097 Query: 1862 TLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK------GKSWTKI 1915 + P P N + ++ S+TL W+ P +P+ NY I F +K G S T+I Sbjct: 1098 RIKPEDVPLNLRAHDVSTHSMTLSWSPPIRL--TPV-NYKISFDAMKVFVDSQGFSQTQI 1154 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENT--VGVSLPTESQSVRLEKHATVPSPPTAP 1972 V + +H + K I +S T V VS S R TV + AP Sbjct: 1155 VPKREIILKHYV-----KTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAP 1208 Score = 49.6 bits (113), Expect = 0.001 Identities = 64/294 (21%), Positives = 121/294 (41%), Gaps = 32/294 (10%) Query: 818 AVITVEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 +++T PT + A PP I + Q V+ G +P PSI W +N + +S + Sbjct: 20 SLLTWTHPTIVDAAHPPEIIRKPQNQGVRVGGVASFYCAARGDPPPSIVWRKNGKKVSGT 79 Query: 877 E---TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTI---DVEKVT 929 + T+ + G +I L I V + D Y+CVA N G + S A +TI D Sbjct: 80 QSRYTVLEQPGGISI-LRIEPVRAGRDDAPYECVAENGVGDAVSADATLTIYEGDKTPAG 138 Query: 930 F--VKHLQKSYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEGRXXXXX 985 F + + E G TV++ C+ + T + W N+ ++ + R +++G Sbjct: 139 FPVITQGPGTRVIEVGHTVLMTCKAIGNPTPNIYWIKNQTKVDMSNPRYSLKDG---FLQ 195 Query: 986 XXXXXXXDVGVIKCIVKD-------QETSTMLVVKETIPEFIRKLQDFE--VKEKDVAIL 1036 D G +C+ ++ + T+ + V+ P F R + + ++ + Sbjct: 196 IENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNLS 255 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 + + S V W + E + P E I + ++ ++ + Y+CI Sbjct: 256 CIAVGSPMPHVKWMKGSEDLTP-------ENEMPIGRNVLQLINIQESANYTCI 302 >UniRef50_UPI0000E4A6A5 Cluster: PREDICTED: similar to heparan sulfate proteoglycan perlecan; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to heparan sulfate proteoglycan perlecan - Strongylocentrotus purpuratus Length = 2331 Score = 98.3 bits (234), Expect = 2e-18 Identities = 211/952 (22%), Positives = 342/952 (35%), Gaps = 105/952 (11%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT +P+ + EG + C P P + W G + + S+ Sbjct: 819 PTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRW--SGGQ-------GGVLNSESTFENG 869 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 + I + E Y A N G A++ VL + + + P I P S V +GE VI Sbjct: 870 LFVIPKARASDEAEYFCEATNSAGMATIRTVLYV-SPSRVPSVTISP-ASESVSEGERVI 927 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 Q G+P P TW + + + + + +G ++ + EGVY A NS G Sbjct: 928 FYCQATGDPAPERTWSRIDGDMPSSAREENG----YLVISAVTYEVEGVYRCTATNSHGS 983 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + A IT+ T+ P I+ EITV + T L T P P+ITW R Sbjct: 984 DYSDAQITIS--TDSRRSPTARIDP-AEITVTQGATQVLRCLTTGVPTPTITWTRG---- 1036 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 S ++ N N L I N D D Y C A+N AG S+ A V I+ + ++ Sbjct: 1037 --SGPLSANQQALNGVLRIINAD-VTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEI 1093 Query: 934 LQKS-YETEEGKTVILECQTSHTVST---KWYH-NKKEISGMDHREIIQEGRXXXXXXXX 988 L S Y +G + ++C+ + T W N +S + E+ Sbjct: 1094 LPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSSNTNDEM------GVLTIMG 1147 Query: 989 XXXXDVGVIKCIVKD---QETSTMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSET 1044 + G C + T+T + + +P+ I E + + A+LE E Sbjct: 1148 VTAENQGAYICTGTNSAGSATATATIRVQGLPQISITPTNPAEFRVGETAVLECVATGEP 1207 Query: 1045 ADVV-W--ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 V W + + +P ++ E+ YI++ S++D G Y C AE Sbjct: 1208 LPTVQWMVMNNERVYQPIAAAFNMEEESSAMH-YIQSVSMNDAGSY-------MCRAENG 1259 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIEL--TKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 + E++ L+ +V +G A F T + W + S + T+ Sbjct: 1260 AGYVEQELL--LRELEVIEGETAVFSCTSPGTPAGYTITWRR------VSQRMPSTVSIS 1311 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 L I AG+Y C VGN ++ + L LP + P T E Sbjct: 1312 NGLLTIPQARSQYAGQYYCIVGNEHGYQ----QDLVTLYVLVLPSLSISP-TTQTVTAGE 1366 Query: 1220 I------PDETLDVT--WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLL 1271 I + T +T W K + T + L I T D +Y CV Sbjct: 1367 IIRISCFAEGTQPITCEWSKYGGSLPPT------AIQSGGILQISPATATDAGQYRCVCS 1420 Query: 1272 DAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 + + + V V P RE R GS V P P W ++ Sbjct: 1421 NTAGFRDSYMTVRVQVIPTVTAIPARETRAIGGS-VEFSCQATGTPPPQITWEKEDGVL- 1478 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNI 1389 +H + L++ + + D G Y N G + + + P+ N Sbjct: 1479 PAQHR-----ITNGVLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNT 1533 Query: 1390 LEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSY 1449 E +TG+ T VV + ++++ ISV + + +I + + Sbjct: 1534 TVHYIRVGETTTFECLSTGDPT---PVVTWTKVNSEMPISVV-LQGARLTIPQVSLSDVG 1589 Query: 1450 RFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP 1509 +R A N V S S+ Y + + + T P+ +E +C+ GG P Sbjct: 1590 FYRCTATNIVG-SRTSQVFLYVQAAPQLTVVPSTRTAPV-------GSTLEFSCLAGGFP 1641 Query: 1510 QPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 P++TW++D L Y+ + Y CIA N G E Sbjct: 1642 TPEITWHKDDGDLPD---NYQIDNGLLTITNVKEADEGTYVCIATNQGGSTE 1690 Score = 79.4 bits (187), Expect = 1e-12 Identities = 81/317 (25%), Positives = 136/317 (42%), Gaps = 29/317 (9%) Query: 640 PKAQYVDEGSDILLECRLVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKIT 698 P+ V EG + CR ++ P IAW + + +P ++ + +L I Sbjct: 734 PQTVEVPEGETVQFVCRGISQTPAYTIAWS-RSDGTLP---------TNARDFMGILTID 783 Query: 699 NVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQV 758 V+ G Y + N+ A L + + +EP IEP + + + +G+ V Sbjct: 784 TVRLSDAGQYVCMGSNQRDTADAYATLIVTSSVQEPTVRIEP-RFIRITEGDRVEFRCIA 842 Query: 759 VGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 GNP PT+ W V L ++S + + + ++ + DE Y +A NS G+A Sbjct: 843 TGNPTPTLRWSGGQGGV--LNSESTFE-NGLFVIPKARASDEAEYFCEATNSAGMATIRT 899 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET 878 V+ V + P + I+ E +V E + + T +P P TW R + + PS Sbjct: 900 VLYV----SPSRVPSVTISPASE-SVSEGERVIFYCQATGDPAPERTWSRIDGDM-PSSA 953 Query: 879 ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI--DVEKVTFVKHLQK 936 EN LVI+ V E++ G Y+C A+NS G A++TI D + + Sbjct: 954 -----REENGYLVISAVTYEVE-GVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPA 1007 Query: 937 SYETEEGKTVILECQTS 953 +G T +L C T+ Sbjct: 1008 EITVTQGATQVLRCLTT 1024 Score = 76.6 bits (180), Expect = 7e-12 Identities = 193/968 (19%), Positives = 355/968 (36%), Gaps = 102/968 (10%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH 787 TG++ P + P ++ V G +++ ++ GN + W + + +P+ G T+ Sbjct: 632 TGDRIPTVIASPTEASSVLGG-TIVFQVRITGN-YTSAQWRRADGQPLSPSAYVEPG-TY 688 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 + I + + D G++ A N G + V + IN Q + V E Sbjct: 689 RLQI-RNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMR-----VVINDPQTVEVPEG 742 Query: 848 GTIKLVAR-VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 T++ V R +++ P +I W R++ + T ++F G L I V D+G Y C Sbjct: 743 ETVQFVCRGISQTPAYTIAWSRSDGTLP---TNARDFMGI---LTIDTVRLS-DAGQYVC 795 Query: 907 VASNSAGKSSHGAR--VTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWYH 962 + SN + A VT V++ T V+ + EG V C + T + +W Sbjct: 796 MGSNQRDTADAYATLIVTSSVQEPT-VRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSG 854 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQET-STMLVVKET-IPEFI 1020 + + ++ + G + T T+L V + +P Sbjct: 855 GQGGV--LNSESTFENGLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVT 912 Query: 1021 RKLQDFEVKEKDVAILEVEINSETA-DVVWER-DGEIIKPKKNKYDFEKRGHIRKLYIRN 1078 V E + I + + A + W R DG++ P + E+ G+ L I Sbjct: 913 ISPASESVSEGERVIFYCQATGDPAPERTWSRIDGDM--PSSAR---EENGY---LVISA 964 Query: 1079 TSVHDEGEYSCILRD----ESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIE-LTK 1132 + EG Y C + + A++T+ + R+ ++ AT + LT Sbjct: 965 VTYEVEGVYRCTATNSHGSDYSDAQITISTDSRRSPTARIDPAEITVTQGATQVLRCLTT 1024 Query: 1133 G--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCT 1186 G + W + + + Q ++G L+I + D+ D YSC G+S T Sbjct: 1025 GVPTPTITWTRGSGPLSAN---QQALNGV---LRIINADVTDRDMYSCTATNIAGSSTAT 1078 Query: 1187 AILTVE--EPSINFTLRLPEFILVPA-NTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFT 1243 A + +E E + L +I + N + T V+W + + Sbjct: 1079 AYVEIERRESPVIEILPYSTYIAIDGDNIQIQCRILSGIPTPTVSWSRANGAPLSSN--- 1135 Query: 1244 LISDVKKRTLIIRKCTEDDQCEYTCVLLDA--KSTTKLKVEVVEFPPKIVDYEREYRIKR 1301 ++ + L I T ++Q Y C ++ +T + V P + + Sbjct: 1136 --TNDEMGVLTIMGVTAENQGAYICTGTNSAGSATATATIRVQGLPQISITPTNPAEFRV 1193 Query: 1302 GSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 G L P P +W+V N ++ + + SA I+ V DAG Y Sbjct: 1194 GETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYM 1253 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEY 1419 R EN G+ + E+ + L+ ++E +++ + C P TI + V Sbjct: 1254 CRAENGAGYVEQELLLRELE---------VIEGETAVFS-C-TSPGTPAGYTITWRRVS- 1301 Query: 1420 QEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 Q + +T IS +T Q S Y + Y + + + Y ++ + Sbjct: 1302 QRMPSTVSISNGLLTIPQA-------RSQYAGQYYCIVGNEHGYQQDLVTLYVLVLPSLS 1354 Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539 SPT + T E I ++C G W + G L ++ Sbjct: 1355 ISPTTQ------TVTAGEIIRISCFAEGTQPITCEWSKYGGSLPPT--AIQSGGILQISP 1406 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y+C+ N G ++ V +Q P +T ++ +G + G Sbjct: 1407 ATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAI--PARETRAIGGSVEFSCQATGT 1464 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 PPP++ W K L ++ IT V+ + L+ +Y A+N AG+S Sbjct: 1465 PPPQITWEKEDGVL--PAQHRIT----NGVLSLISLRDGDEGRYVCTATNQAGSSKAYAR 1518 Query: 1660 LKVYDKPS 1667 L ++ P+ Sbjct: 1519 LFLHAAPT 1526 Score = 73.7 bits (173), Expect = 5e-11 Identities = 70/305 (22%), Positives = 118/305 (38%), Gaps = 31/305 (10%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PT + P + G + C+ P P I W K + ++P ++ + Sbjct: 1438 PTVTAIPARETRAIGGSVEFSCQATGTPPPQITWE-KEDGVLPAQH---------RITNG 1487 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 VL + +++ EG Y A N+ G + L + Q+ +R GE+ Sbjct: 1488 VLSLISLRDGDEGRYVCTATNQAGSSKAYARLFLHAAPTV--QITVNTTVHYIRVGETTT 1545 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 G+P P +TW K N +P +TI + + D G Y A N G Sbjct: 1546 FECLSTGDPTPVVTWTKVNSE---MPISVVLQGARLTIPQVS-LSDVGFYRCTATNIVGS 1601 Query: 814 AETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII 873 + + V+ + P T T++ P P ITW++++ Sbjct: 1602 RTSQVFLYVQAAPQLTVVP-------STRTAPVGSTLEFSCLAGGFPTPEITWHKDDG-- 1652 Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + N+ +N L ITNV E D G Y C+A+N G + H AR+ + E + + Sbjct: 1653 ----DLPDNYQIDNGLLTITNV-KEADEGTYVCIATNQGGSTEHRARLVVG-ELIPYFVQ 1706 Query: 934 LQKSY 938 + +SY Sbjct: 1707 MPQSY 1711 Score = 72.1 bits (169), Expect = 2e-10 Identities = 147/726 (20%), Positives = 269/726 (37%), Gaps = 94/726 (12%) Query: 599 IVEAPLSDHGS-EMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVD-EGSDILLECR 656 I+ A ++D T +I P P + Y+ +G +I ++CR Sbjct: 1053 IINADVTDRDMYSCTATNIAGSSTATAYVEIERRESPVIEILPYSTYIAIDGDNIQIQCR 1112 Query: 657 LVA-IPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNR 715 +++ IP P ++W + S+ + VL I V +G Y N Sbjct: 1113 ILSGIPTPTVSW---------SRANGAPLSSNTNDEMGVLTIMGVTAENQGAYICTGTNS 1163 Query: 716 EGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNK 773 G A+ ++++ PQ+ I P R GE+ +L G P PT+ W NN+ Sbjct: 1164 AGSATATATIRVQG----LPQISITPTNPAEFRVGETAVLECVATGEPLPTVQWMVMNNE 1219 Query: 774 PVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA 830 V A + ++ ++ ++ + D G Y +AEN G E ++ E E Sbjct: 1220 RVYQPIAAAFNMEEESSAMHYIQSVSMNDAGSYMCRAENGAGYVEQELLLRELEVIE--G 1277 Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 E +F + GT A T ITW R ++ + + +I+ L Sbjct: 1278 ETAVF-------SCTSPGT---PAGYT------ITWRRVSQRMPSTVSISNGL------L 1315 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 I S+ +G Y C+ N G VT+ V + + + G+ + + C Sbjct: 1316 TIPQARSQY-AGQYYCIVGNEHGYQQD--LVTLYVLVLPSLSISPTTQTVTAGEIIRISC 1372 Query: 951 --QTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ---E 1005 + + ++ +W + G IQ G D G +C+ + Sbjct: 1373 FAEGTQPITCEW----SKYGGSLPPTAIQSG--GILQISPATATDAGQYRCVCSNTAGFR 1426 Query: 1006 TSTMLVVKETIPEFIR-KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYD 1064 S M V + IP ++ V + + WE++ ++ P +++ Sbjct: 1427 DSYMTVRVQVIPTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVL-PAQHRI- 1484 Query: 1065 FEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV---TVVELPP--EIITRLQNQKVN 1119 G + + +R+ DEG Y C +++ +++ + P +I + Sbjct: 1485 --TNGVLSLISLRD---GDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIR 1539 Query: 1120 KGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYS 1177 G TFE L+ GD +V W K SE+ I + + G +L I L D G Y Sbjct: 1540 VGETTTFEC-LSTGDPTPVVTWTKVNSEMP----ISVVLQG--ARLTIPQVSLSDVGFYR 1592 Query: 1178 CEVGN---SKCTAILTVEEPSINFTLRLPEFILVP-ANTDAYLTVEIPDETLDVTWYKKK 1233 C N S+ + + + + T+ +P P +T + + T ++TW+K Sbjct: 1593 CTATNIVGSRTSQVFLYVQAAPQLTV-VPSTRTAPVGSTLEFSCLAGGFPTPEITWHKDD 1651 Query: 1234 SVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIV 1291 + D + + L I E D+ Y C+ + +T+ + +V E P V Sbjct: 1652 GDLPDNYQ------IDNGLLTITNVKEADEGTYVCIATNQGGSTEHRARLVVGELIPYFV 1705 Query: 1292 DYEREY 1297 + Y Sbjct: 1706 QMPQSY 1711 Score = 68.1 bits (159), Expect = 2e-09 Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 19/261 (7%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L+I N++ G + A NR G + + L++ G+ + +P +++ V +GE+V Sbjct: 690 LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEV-VGQAMRVVINDP-QTVEVPEGETVQF 747 Query: 755 SAQVVGN-PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGI 813 + + P TI W +++ LPT + D I + ++ D G Y N Sbjct: 748 VCRGISQTPAYTIAWSRSDG---TLPTNAR-DFMGILTIDTVRLSDAGQYVCMGSNQRDT 803 Query: 814 AETSAVITVEEPTEENAEPPLFIN-RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 A+ A + V T EP + I RF IT ++ + +A T NP P++ W Sbjct: 804 ADAYATLIV---TSSVQEPTVRIEPRFIRITEGDRVEFRCIA--TGNPTPTLRWSGGQGG 858 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 + SE+ +N L + D +Y C A+NSAG ++ + + +V V Sbjct: 859 VLNSESTFEN------GLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVT 912 Query: 933 HLQKSYETEEGKTVILECQTS 953 S EG+ VI CQ + Sbjct: 913 ISPASESVSEGERVIFYCQAT 933 Score = 54.4 bits (125), Expect = 3e-05 Identities = 66/341 (19%), Positives = 130/341 (38%), Gaps = 26/341 (7%) Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP--GKPNILEI-DSSSIN-IC 1400 L I+ + DAGI+ N G E+ + ++ + P +E+ + ++ +C Sbjct: 690 LQIRNLRANDAGIFIFTASNRFGSGTAEVRLEVVGQAMRVVINDPQTVEVPEGETVQFVC 749 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 G S Y + + D T + ++ T I ++ + + ++ N+ D Sbjct: 750 ------RGISQTPAYTIAWSRSDGTLPTNARDFMGILT-IDTVRLSDAGQYVCMGSNQRD 802 Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 +DA Y +I + +Q PTV + I + +E CI G P P + W Sbjct: 803 TADA-----YATLIVTSSVQEPTVRIEPRFIRITEGDRVEFRCIATGNPTPTLRWSGGQG 857 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 + +++T+EN Y C A N G V+ + V +++ Sbjct: 858 GVLNSESTFEN-GLFVIPKARASDEAEYFCEATNSAGMATIRTVLYVSPSRVPSVTISPA 916 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 + G+ + G P PE W ++++ D + +E+ + I + Sbjct: 917 SESVSEGERVIFYCQATGDPAPERTW----SRIDGDMP--SSAREENGYLVISAVTYEVE 970 Query: 1641 SKYTIEASNTAGT--SSVEVTLKVYDKPSKPEGPVIMREIS 1679 Y A+N+ G+ S ++T+ D P + EI+ Sbjct: 971 GVYRCTATNSHGSDYSDAQITIST-DSRRSPTARIDPAEIT 1010 Score = 52.0 bits (119), Expect = 2e-04 Identities = 29/79 (36%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 522 PDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 P GST++F C G+P P+ITW K D Y DN L I V D GT+ Sbjct: 1626 PVGSTLEFSCLAGGFPTPEITWH------KDDGDLPDNYQIDN-GLLTITNVKEADEGTY 1678 Query: 582 TCVAKNAAGFASSTTELIV 600 C+A N G L+V Sbjct: 1679 VCIATNQGGSTEHRARLVV 1697 Score = 44.4 bits (100), Expect = 0.035 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 7/79 (8%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +V+F CQ G P PQITW ++ ++ P+Q + + V +L+ + D G + C Sbjct: 1452 GGSVEFSCQATGTPPPQITWEKEDGVL-PAQ----HRITNGVLSLI--SLRDGDEGRYVC 1504 Query: 584 VAKNAAGFASSTTELIVEA 602 A N AG + + L + A Sbjct: 1505 TATNQAGSSKAYARLFLHA 1523 Score = 43.6 bits (98), Expect = 0.061 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 7/80 (8%) Query: 523 DGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 DG +Q +C++ G P P ++W R S +D + L I V E+ G + Sbjct: 1103 DGDNIQIQCRILSGIPTPTVSWSRANGAPLSSNT------NDEMGVLTIMGVTAENQGAY 1156 Query: 582 TCVAKNAAGFASSTTELIVE 601 C N+AG A++T + V+ Sbjct: 1157 ICTGTNSAGSATATATIRVQ 1176 Score = 43.2 bits (97), Expect = 0.081 Identities = 70/331 (21%), Positives = 116/331 (35%), Gaps = 30/331 (9%) Query: 1336 PSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP--NILEID 1393 P+ L I TDAG Y+ N G D M V + P+ P I Sbjct: 1393 PTAIQSGGILQISPATATDAGQYRCVCSNTAGFRDSYMTVRVQVIPTVTAIPARETRAIG 1452 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRA 1453 S C + TG + +++ D + IT S+ +L+ R+ Sbjct: 1453 GSVEFSC----QATGTPPP---QITWEKEDGV-LPAQHRITNGVLSLISLRDGDEGRYVC 1504 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNIT--TEPNEDIELTCIFGGVPQP 1511 A N+ S A Y ++ +PTV+ + E C+ G P P Sbjct: 1505 TATNQAGSSKA-----YARLFLHA---APTVQITVNTTVHYIRVGETTTFECLSTGDPTP 1556 Query: 1512 KVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKP 1571 VTW + ++ + R Y+C A N G + + +Q P Sbjct: 1557 VVTWTKVNSEMPISVVLQGARLTIPQVSLSDVGF--YRCTATNIVGSRTSQVFLYVQAAP 1614 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIR 1631 +T+ + VG + + G P PE+ W+K+ L ++ Y I ++ Sbjct: 1615 QLTVVPST--RTAPVGSTLEFSCLAGGFPTPEITWHKDDGDLPDN--YQI----DNGLLT 1666 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 I +K + Y A+N G++ L V Sbjct: 1667 ITNVKEADEGTYVCIATNQGGSTEHRARLVV 1697 Score = 41.5 bits (93), Expect = 0.25 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 5/93 (5%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF--RQTAIIKP-SQDFQM 558 T Q + I + P G T EC G P P + W + +P + F M Sbjct: 1172 TIRVQGLPQISITPTNPAEFRVGETAVLECVATGEPLPTVQWMVMNNERVYQPIAAAFNM 1231 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 ++++ A I+ V DAG++ C A+N AG+ Sbjct: 1232 --EEESSAMHYIQSVSMNDAGSYMCRAENGAGY 1262 Score = 40.3 bits (90), Expect = 0.57 Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 8/185 (4%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXX 1541 PTV T +E +C G P P++TW ++ L A+ N Sbjct: 1438 PTVTAIPARETRAIGGSVEFSCQATGTPPPQITWEKEDGVLP-AQHRITN-GVLSLISLR 1495 Query: 1542 XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C A N G + + + P + I+ +VG+ + G P Sbjct: 1496 DGDEGRYVCTATNQAGSSKAYARLFLHAAPTVQITVNTTVHYIRVGETTTFECLSTGDPT 1555 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P V W K + E I+ + + + I ++ S Y A+N G+ + +V L Sbjct: 1556 PVVTWTK------VNSEMPISVVLQGARLTIPQVSLSDVGFYRCTATNIVGSRTSQVFLY 1609 Query: 1662 VYDKP 1666 V P Sbjct: 1610 VQAAP 1614 Score = 38.3 bits (85), Expect = 2.3 Identities = 26/79 (32%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T FEC G P P +TW + + + S Q A L I +V D G + C Sbjct: 1541 GETTTFECLSTGDPTPVVTWTKVNSEMPISVVLQ-------GARLTIPQVSLSDVGFYRC 1593 Query: 584 VAKNAAGFASSTTELIVEA 602 A N G +S L V+A Sbjct: 1594 TATNIVGSRTSQVFLYVQA 1612 >UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; n=3; Danio rerio|Rep: hypothetical protein LOC553690 - Danio rerio Length = 981 Score = 98.3 bits (234), Expect = 2e-18 Identities = 107/472 (22%), Positives = 184/472 (38%), Gaps = 32/472 (6%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 F+K+PK Q G +L C + +W+ GE + E + L Sbjct: 1 FTKEPKPQDALHGRSAMLRCEVNDPQGVSYSWIQNGEPVTNSER--------RFLDGGNL 52 Query: 696 KITNVKK-FQEGTYTVVAVNR---EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 K T + + G + +A E E + IK E + P ++ Sbjct: 53 KFTAIDRTLDSGNFQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQ 112 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 VIL + G PRPT W K+ + K + S+T+L D G+Y A+N+ Sbjct: 113 VILRCNIDGYPRPTNRWFKDGTQITEKNYKINNKERSVTLLNASP-DDNGLYHCCAKNAA 171 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G +S T+ + +P + + +++ V + + T P+P++ WY NE Sbjct: 172 GQVCSSDNFTLNIIDKSFPQP---LVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENE 228 Query: 872 II-SPSET--ITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEK 927 ++ + S T + F N L+IT V + ++G YKCVA G S A + I E Sbjct: 229 LVANKSRTGHFIRVFILSNGSLLITQV-KQRNTGLYKCVAQGPRGPPVSLEASLRI-AEI 286 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + + + + + V H W+ + DH + Q+G Sbjct: 287 EDMMAKQSRVFSADSLERVTCRAPYGHPQPEVWWERAGQ-RVPDHGRVFQKGH--DLIFS 343 Query: 988 XXXXXDVGVIKCIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE- 1043 D G+ C ++ Q+ + V T PE+++K D +++E L + Sbjct: 344 PTHGEDSGIYTCFAQNKAGQKKQELTVTVATKPEWVQKPVDSQLEEGRAGFLHCHTRANP 403 Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES 1095 V W R+ + I + ++ G +R I N V+D YSC R E+ Sbjct: 404 EPQVTWYRNLQPISAEDVRFKLFSNGTLR---INNVEVYDGHMYSCESRTEA 452 Score = 64.5 bits (150), Expect = 3e-08 Identities = 86/380 (22%), Positives = 150/380 (39%), Gaps = 39/380 (10%) Query: 1034 AILEVEINS-ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR 1092 A+L E+N + W ++GE + + + F G+++ I T D G + CI Sbjct: 16 AMLRCEVNDPQGVSYSWIQNGEPVTNSERR--FLDGGNLKFTAIDRTL--DSGNFQCIAS 71 Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVN-KGNKATFEIELTKGDALV-----------RWF 1140 S E E I L++ V+ K ++ EI+ + L RWF Sbjct: 72 KNSTGEEERTAETSFNI-KWLESGAVSLKSPESVAEIQSSSQVILRCNIDGYPRPTNRWF 130 Query: 1141 KDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK---CTA---ILTVEEP 1194 KDG++I N+ I+ K++ + + + DD G Y C N+ C++ L + + Sbjct: 131 KDGTQITEKNY---KINNKERSVTLLNASPDDNGLYHCCAKNAAGQVCSSDNFTLNIIDK 187 Query: 1195 SINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKSVIED---TEKFTLISDVKK 1250 S L PE ++V N +A + E + V WY + ++ + T F + + Sbjct: 188 SFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEWYHENELVANKSRTGHFIRVFILSN 247 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKS---TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL 1307 +L+I + + + Y CV + + + + + E + R + VT Sbjct: 248 GSLLITQVKQRNTGLYKCVAQGPRGPPVSLEASLRIAEIEDMMAKQSRVFSADSLERVTC 307 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 Y PQP W + + H + + K L D+GIY +N G Sbjct: 308 RAPY-GHPQPEVWWERAGQRVPD--HGR--VFQKGHDLIFSPTHGEDSGIYTCFAQNKAG 362 Query: 1368 HADVEMNVTILDKPSPPGKP 1387 E+ VT+ KP KP Sbjct: 363 QKKQELTVTVATKPEWVQKP 382 Score = 54.4 bits (125), Expect = 3e-05 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 8/96 (8%) Query: 513 VEKLRPKHTP--DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQD-FQMYYDDDNVATLV 569 V KL+P++T G T CQ G P P I W ++ ++ + FQ + +LV Sbjct: 509 VFKLKPENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKMAN----GSLV 564 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAPL 604 I +V ED G++TC+A N+ A ++ EL +VE P+ Sbjct: 565 IHDVSTEDTGSYTCIAGNSCNIAHTSAELYVVEKPV 600 Score = 52.0 bits (119), Expect = 2e-04 Identities = 85/393 (21%), Positives = 137/393 (34%), Gaps = 46/393 (11%) Query: 476 DENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEG 535 D YT + Q K +K +L V + P +V+K +G C Sbjct: 349 DSGIYTCFAQNKAGQKKQELTV-------TVATKPEWVQKPVDSQLEEGRAGFLHCHTRA 401 Query: 536 YPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASST 595 P PQ+TW+R ++P + + + TL I V D ++C ++ AG ++ Sbjct: 402 NPEPQVTWYRN---LQPISAEDVRFKLFSNGTLRINNVEVYDGHMYSCESRTEAGRVNAQ 458 Query: 596 TELIVEAP-----------LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQY 644 + V A + + + F KP+ Sbjct: 459 ARVFVLAKGRQTPTIHWMRTGQQDNAACHKAQSSQISVESRVSVFCSVYVVFKLKPENTT 518 Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V +G +L C+ P P I W K D+ + M L I +V Sbjct: 519 VYQGHTAVLHCQATGDPPPFIQWKKK------DKFLEAGKSRFQKMANGSLVIHDVSTED 572 Query: 705 EGTYTVVAVN----REGEASLPIVLK-----IKTGEKEPPQVIEPLKSMIVRQGESVILS 755 G+YT +A N A L +V K + EK P ++I+ + + G +V Sbjct: 573 TGSYTCIAGNSCNIAHTSAELYVVEKPVQHSLSDDEKTPYKMIQTIGLSV---GAAVAYI 629 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 V+G + +CK + K L DGD + L +V+ G T AE E +A Sbjct: 630 IIVLG----LMFYCKQRRNAKRLQKGQDGDEREVECLN-GEVQQNGHTT--AEIQEEVAL 682 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKG 848 T+ + E L R T+ G Sbjct: 683 TNMAAAGNNKRHSSHESKLQFPRSNLHTITTLG 715 Score = 51.6 bits (118), Expect = 2e-04 Identities = 72/375 (19%), Positives = 143/375 (38%), Gaps = 23/375 (6%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 I+ S V L + +P+P + W + I + K+ K I++K S+T+ D G+Y Sbjct: 107 IQSSSQVILRCNIDGYPRPTNRWFKDGTQITE-KNYK--INNKERSVTLLNASPDDNGLY 163 Query: 1359 KLRLENNCGHADVEMNVT--ILDK--PSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 +N G N T I+DK P P KP L + + + + + + Sbjct: 164 HCCAKNAAGQVCSSDNFTLNIIDKSFPQPLVKPEDLVVMKNEEAVFHCQFTAEPMPAVEW 223 Query: 1415 Y---VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY 1471 Y + + T +I V ++ I +K ++ ++ A + E + Sbjct: 224 YHENELVANKSRTGHFIRVFILSNGSLLITQVKQRNTGLYKCVAQGPRGPPVSLEAS--- 280 Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 ++ +I+ + K + + + E + +G PQP+V W R G+++ ++ Sbjct: 281 --LRIAEIED-MMAKQSRVFSADSLERVTCRAPYGH-PQPEVWWERAGQRVPDHGRVFQK 336 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C A N G+ + V + KP + + + + G Sbjct: 337 GHDLIFSPTHGEDSGIYTCFAQNKAGQKKQELTVTVATKPEWV--QKPVDSQLEEGRAGF 394 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLE-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNT 1650 + P P+V WY+N + D + + + +RI ++ Y+ E+ Sbjct: 395 LHCHTRANPEPQVTWYRNLQPISAEDVRFKLFS---NGTLRINNVEVYDGHMYSCESRTE 451 Query: 1651 AGTSSVEVTLKVYDK 1665 AG + + + V K Sbjct: 452 AGRVNAQARVFVLAK 466 Score = 45.2 bits (102), Expect = 0.020 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S V C ++GYPRP WF+ I Y ++ ++ + P+D G + C Sbjct: 111 SQVILRCNIDGYPRPTNRWFKDGTQITEKN----YKINNKERSVTLLNASPDDNGLYHCC 166 Query: 585 AKNAAGFASST 595 AKNAAG S+ Sbjct: 167 AKNAAGQVCSS 177 Score = 42.7 bits (96), Expect = 0.11 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 15/141 (10%) Query: 1548 YKCIAF-NDHGE----VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPP 1602 ++CIA N GE ETS + + +++ + + + + + ++ I+G P P Sbjct: 66 FQCIASKNSTGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVILRCNIDGYPRP 125 Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG--TSSVEVTL 1660 W+K+G ++ +K Y I KE++ + + + Y A N AG SS TL Sbjct: 126 TNRWFKDGTQI-TEKNYKINNKERS--VTLLNASPDDNGLYHCCAKNAAGQVCSSDNFTL 182 Query: 1661 KVYDK--PS---KPEGPVIMR 1676 + DK P KPE V+M+ Sbjct: 183 NIIDKSFPQPLVKPEDLVVMK 203 Score = 40.3 bits (90), Expect = 0.57 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Query: 840 QEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEI 899 + TV + T L + T +P P I W + ++ + ++ Q N LVI +V +E Sbjct: 515 ENTTVYQGHTAVLHCQATGDPPPFIQWKKKDKFLEAGKSRFQKM--ANGSLVIHDVSTE- 571 Query: 900 DSGDYKCVASNSAGKSSHGARVTIDVEK 927 D+G Y C+A NS + A + + VEK Sbjct: 572 DTGSYTCIAGNSCNIAHTSAELYV-VEK 598 >UniRef50_A1L1W0 Cluster: Zgc:158442; n=3; Danio rerio|Rep: Zgc:158442 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 523 Score = 98.3 bits (234), Expect = 2e-18 Identities = 76/308 (24%), Positives = 141/308 (45%), Gaps = 25/308 (8%) Query: 1295 REYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 R+ IK+ G + L++ +Q P+P W N + + + + D+ + L I++ E Sbjct: 221 RQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTI-LFIRRSERK 279 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 D+G Y ++++ +N+ I+D P PP ++++ ++ + W P++ GN I Sbjct: 280 DSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKDNGNCDIT 339 Query: 1414 YYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 Y ++ + T EW +V + +T + +L + Y FR YA N V +S ++ Sbjct: 340 GYNIQKADKKTMEWYTVFEQYRRTNCVVSDLIMGNEYVFRVYAANMVGLSPEPCLSKDSA 399 Query: 1473 VIKETKI-------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG 1519 I++T I ++P PLK+ + + L+C G+ +PK+TWY++ Sbjct: 400 YIQKTGIVYKPPSYKDHDFSEAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNK 459 Query: 1520 KKLKTAKATY---ENRXXXXXXXXX--XXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 + T +A Y N+ Y C A ND GE C + + + P +T Sbjct: 460 MDI-TNEAKYRMFSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDLVECKLEV-RLPQVT 517 Query: 1575 ISNEDIKQ 1582 EDIK+ Sbjct: 518 --KEDIKK 523 Score = 88.2 bits (209), Expect = 2e-15 Identities = 56/187 (29%), Positives = 92/187 (49%), Gaps = 8/187 (4%) Query: 1567 IQQKPVITISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 I Q+P I + +++Q KVG+ + +G P P+V W KN L+ K +I Sbjct: 208 IMQRPKIWLPR-NLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLD-PKSVSIRNS 265 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVT 1684 + +++ I+ +R S KY ++ V +++ D P P+ +M ++ +V Sbjct: 266 DTDTILFIRRSERKDSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVM-DVWGFNVA 324 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIA 1743 +EWKPP D+G ++T Y I+K + W V + R T C + L EY+FRV A Sbjct: 325 LEWKPPKDNGNCDITGYNIQKADKKTMEWYTVFEQYR--RTNCVVSDLIMGNEYVFRVYA 382 Query: 1744 QNPVGFS 1750 N VG S Sbjct: 383 ANMVGLS 389 Score = 60.9 bits (141), Expect = 4e-07 Identities = 72/312 (23%), Positives = 120/312 (38%), Gaps = 19/312 (6%) Query: 1754 ESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-K 1812 E +P + P+ I + ++ + W E+ G + + Y VE +EG + Sbjct: 97 EPQPAPEPEPVGTPTSEPIGLCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDE 156 Query: 1813 W--KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--Q 1868 W I+ L QFR+ A N G S P T +TI + + P Sbjct: 157 WIPAFSGLTERTSVIIRDLPTGEKMQFRVRAYNMAGPSAPATLQQAVTIREIMQRPKIWL 216 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC-- 1926 PRN + T+ P P ++ + + KS V++ S + Sbjct: 217 PRNLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKS----VSIRNSDTDTILF 272 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I + KD + + + + + SV ++ VP PP + + G N+ + Sbjct: 273 IRRSERKDSGKYDVQVQ----IENVEDKASVNIQI-VDVPGPPQNLKVMDVWGFNVAL-E 326 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P+ +G + GYNI D W V + T + DL + Y+ R+YA N Sbjct: 327 WKPPKDNGNCDITGYNIQKADKKTMEWYTVFEQYRRT-NCVVSDLIMGNEYVFRVYAANM 385 Query: 2047 IGLS-EPLESDE 2057 +GLS EP S + Sbjct: 386 VGLSPEPCLSKD 397 Score = 59.3 bits (137), Expect = 1e-06 Identities = 58/240 (24%), Positives = 99/240 (41%), Gaps = 26/240 (10%) Query: 1380 KPSPPGKPN-------ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI-SVK 1431 +P P G P + +I ++I++ W PE G++ + Y VEY + + EWI + Sbjct: 103 EPEPVGTPTSEPIGLCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDEWIPAFS 162 Query: 1432 NIT-KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP--- 1487 +T +T I++L T +FR A N S A T + I+E +Q P + P Sbjct: 163 GLTERTSVIIRDLPTGEKMQFRVRAYNMAGPS-APATLQQAVTIREI-MQRPKIWLPRNL 220 Query: 1488 LKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXX 1547 + + + E I L F G P+P+V+W ++ + L + N Sbjct: 221 RQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSER-- 278 Query: 1548 YKCIAFNDHGEVETSC-VVGIQQKPVITISNEDI---KQKHKVGDEWLVTAVIEGIPPPE 1603 D G+ + + ++ K + I D+ Q KV D W +E PP + Sbjct: 279 ------KDSGKYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKD 332 Score = 55.2 bits (127), Expect = 2e-05 Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 4/115 (3%) Query: 492 IDKLPVFEKPTSEEQ---SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 I K + KP S + S AP F L+ + G C V G +P+ITW++ Sbjct: 401 IQKTGIVYKPPSYKDHDFSEAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNKM 460 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I ++M + + V TL IR+ P D G + C A N +G +L V P Sbjct: 461 DITNEAKYRM-FSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDLVECKLEVRLP 514 Score = 53.2 bits (122), Expect = 8e-05 Identities = 67/311 (21%), Positives = 123/311 (39%), Gaps = 17/311 (5%) Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 S+P G + + +IS +++++W+ P G EL Y +E + ++ WI + + Sbjct: 112 SEPIG-LCVDDISDTTISLKWRTPERIGSAELEGYGVEYCKEGSDEWIPAFSGLTERTSV 170 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 I+ L + FRV A N G S P ++ A+ + + I Sbjct: 171 IIRDLPTGEKMQFRVRAYNMAG-----PSAPATLQQAVTIREIMQRPKIWLPRNLRQTLI 225 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 N +I ++ + + + K I+ +T R R + G Sbjct: 226 KKVGETIN---LVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSERKDSG 282 Query: 1847 TSLPYTS----DDKITIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYI 1901 +DK ++ + + P P+N V + +V L+W P+ NG IT Y Sbjct: 283 KYDVQVQIENVEDKASVNIQIVDVPGPPQNLKVMDVWGFNVALEWKPPKDNGNCDITGYN 342 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS-LPTESQ-SVRL 1959 I+ K W + + + ++ +E +FR+ A N VG+S P S+ S + Sbjct: 343 IQKADKKTMEWYTVFEQYRRTN-CVVSDLIMGNEYVFRVYAANMVGLSPEPCLSKDSAYI 401 Query: 1960 EKHATVPSPPT 1970 +K V PP+ Sbjct: 402 QKTGIVYKPPS 412 Score = 44.0 bits (99), Expect = 0.046 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 4/90 (4%) Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDE 800 +++I + GE++ L G PRP ++W KN++P+ + DT +I ++ + KD Sbjct: 222 QTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNSDTDTILFIRRSERKDS 281 Query: 801 GVYTLKA--ENSEGIAETS-AVITVEEPTE 827 G Y ++ EN E A + ++ V P + Sbjct: 282 GKYDVQVQIENVEDKASVNIQIVDVPGPPQ 311 Score = 43.2 bits (97), Expect = 0.081 Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 4/101 (3%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 E P+ PLKS V G + LS V G +P ITW KN + + L Sbjct: 420 EAPKFTHPLKSRSVIAGYNATLSCSVRGISKPKITWYKNKMDITNEAKYRMFSNQGVLTL 479 Query: 793 KPKK--VKDEGVYTLKAENSEG--IAETSAVITVEEPTEEN 829 + +K D GVY KA N G + E + + + T+E+ Sbjct: 480 EIRKPCPFDGGVYMCKAVNDSGEDLVECKLEVRLPQVTKED 520 Score = 39.5 bits (88), Expect = 0.99 Identities = 18/67 (26%), Positives = 33/67 (49%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + GI P++ WYKN + N+ +Y + + + + I++ Y +A N +G Sbjct: 445 VRGISKPKITWYKNKMDITNEAKYRMFSNQGVLTLEIRKPCPFDGGVYMCKAVNDSGEDL 504 Query: 1656 VEVTLKV 1662 VE L+V Sbjct: 505 VECKLEV 511 Score = 39.1 bits (87), Expect = 1.3 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 5/141 (3%) Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 + +CK + +P S + I++ ++ + ++A N G + + + Sbjct: 147 VEYCKEGSD-EWIPAFSGLTERTSVIIRDLPTGEKMQFRVRAYNMAGPSAPATLQQAVTI 205 Query: 826 TEENAEPPLFINR-FQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNF 883 E P +++ R ++ +K+ G TI LV P P ++W +N+E + P +N Sbjct: 206 REIMQRPKIWLPRNLRQTLIKKVGETINLVIPFQGKPRPQVSWTKNDEPLDPKSVSIRNS 265 Query: 884 DGENIELVITNVDSEIDSGDY 904 D + I L I + + DSG Y Sbjct: 266 DTDTI-LFIRRSERK-DSGKY 284 >UniRef50_Q967D7 Cluster: Protein turtle; n=5; Drosophila melanogaster|Rep: Protein turtle - Drosophila melanogaster (Fruit fly) Length = 1531 Score = 98.3 bits (234), Expect = 2e-18 Identities = 106/453 (23%), Positives = 199/453 (43%), Gaps = 38/453 (8%) Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 D IL + + + T +++W +D + P F +R IR+ D GEY+CI Sbjct: 269 DSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRH---EDIGEYTCI 325 Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141 R+ S TA V V+ +PP T+L+ +KV + E + G+ VRW++ Sbjct: 326 ARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVI----FSCEAKAMPGNVTVRWYR 381 Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEPS 1195 +GS ++ ++ + +K L I DD+G+Y CEV N +A L+VE P+ Sbjct: 382 EGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPA 441 Query: 1196 -INFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLI 1254 + FT + +++ ++ + VTW K K ++E + ++ + +L+ Sbjct: 442 KVTFTPTV-QYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVV-MANGSLL 499 Query: 1255 IRKCTEDDQCEYTCVLLDAKSTT----KLKVEVVEFPPKIVDYEREYRIKRGSDVTL--- 1307 + E+ Q +Y C +A+ T + V V + P V+ E Y+ K G V + Sbjct: 500 FTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCD 559 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 ++ + +P +W + + + + I ++TI+ + D G Y+ + N Sbjct: 560 ALEAEGTERPTIKW-QRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVA 618 Query: 1368 HADVEMNVTILDKPSPPGKPNIL-EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE 1426 + + +++ P NI + SSI + W + G+ Y + ++E + Sbjct: 619 TL-MAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVND 677 Query: 1427 W--ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 W ISV TQ +I L + ++Y F+ N Sbjct: 678 WQTISVTPSGSTQVTINGLASGTTYEFQVVGRN 710 Score = 91.9 bits (218), Expect = 2e-16 Identities = 92/398 (23%), Positives = 161/398 (40%), Gaps = 32/398 (8%) Query: 633 PPTFSKKPK-AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP FS P+ YV+ G I+L C+ P P+I W + P + + + Sbjct: 252 PPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDG----- 306 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I+ ++ G YT +A N EG+ S + I G ++ P + +GE Sbjct: 307 -TELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGG----AVIMVPPTNQTKLEGEK 361 Query: 752 VILSAQVVGNP-RPTITWCKNNKPVK---ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 VI S + P T+ W + PV+ AL T+ I+ P K D G Y + Sbjct: 362 VIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEV 421 Query: 808 ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G ++ SA ++VE P + P + Q + + G ++ + + + +TW Sbjct: 422 TNGIGDPQSASAYLSVEYPAKVTFTPTV-----QYLPFRLAGVVQCYIK-SSPQLQYVTW 475 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 ++ ++ P + + N L+ T V+ E G Y C N+ G + + + V Sbjct: 476 TKDKRLLEPYQ-MKDIVVMANGSLLFTRVNEE-HQGQYACTPYNAQGTAGASGVMDVLVR 533 Query: 927 K-VTFVKHLQKSYETEEGKTVILECQTSHTVST-----KWYHNKKEISGMDHREIIQEGR 980 K F + Y+ + G +V + C T KW + E R I+ Sbjct: 534 KPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKIS- 592 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPE 1018 D G +C+V + E +T++ V + + E Sbjct: 593 GGNITIENLRREDFGYYQCVVSN-EVATLMAVTQLVIE 629 Score = 65.3 bits (152), Expect = 2e-08 Identities = 105/500 (21%), Positives = 177/500 (35%), Gaps = 32/500 (6%) Query: 1284 VEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 V PP+ V E + G + L P P W ++ + I + Sbjct: 249 VHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTV--GIFNDG 306 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 L I + + D G Y N G V I P N +++ + Sbjct: 307 TELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSC 366 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN-LKTNSSYRFRAYAVNEVD 1460 + GN T+ +Y + + I K + I N +K + S ++ N Sbjct: 367 EAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTN--G 424 Query: 1461 ISDASETTEYYKVIKETKIQ-SPTVEK-PLKNITTEPNEDIELTCIFGGVPQPK-VTWYR 1517 I D + Y V K+ +PTV+ P + + C PQ + VTW + Sbjct: 425 IGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGV-------VQCYIKSSPQLQYVTWTK 477 Query: 1518 DGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI--QQKPV 1572 D + L+ + Y C +N G S V+ + ++ P Sbjct: 478 DKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPA 537 Query: 1573 ITISNEDIKQKHKVGD--EWLVTAV-IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV 1629 T+ E + Q+ KVGD E A+ EG P + W + + + + N K Sbjct: 538 FTVEPETLYQR-KVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRN-RIKISGGN 595 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK 1688 I I+ L+R Y SN T L + + ++P P I + + S+T++W Sbjct: 596 ITIENLRREDFGYYQCVVSNEVATLMAVTQLVI--EGTQPHAPYNITGKATESSITLQWL 653 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 P G Y I E N W ++ I L Y F+V+ +N +G Sbjct: 654 PGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLG 713 Query: 1749 FSEALESEPIVIKTALDVPS 1768 + + S+ + ++T D P+ Sbjct: 714 --DGMMSKVMTVRTLEDAPA 731 Score = 63.3 bits (147), Expect = 7e-08 Identities = 68/261 (26%), Positives = 109/261 (41%), Gaps = 20/261 (7%) Query: 684 IESDMHMYCSVLKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 + D + L +TN+++ +G Y VV +NR+ + P + P Sbjct: 201 VSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPE 260 Query: 742 KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEG 801 + V G+S+IL+ Q G P P I W K+ PV PT + + + + +D G Sbjct: 261 DIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIG 320 Query: 802 VYTLKAENSEG-IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 YT A N EG ++ T+ VI PP + + EK A+ Sbjct: 321 EYTCIARNGEGQVSHTARVIIAGGAV--IMVPPTNQTKLE----GEKVIFSCEAKAMPGN 374 Query: 861 VPSITWYRN----NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KS 915 V ++ WYR E+ + +T DG L+I + + DSG Y C +N G Sbjct: 375 V-TVRWYREGSPVREVAALETRVTIRKDG---SLIINPIKPD-DSGQYLCEVTNGIGDPQ 429 Query: 916 SHGARVTIDV-EKVTFVKHLQ 935 S A ++++ KVTF +Q Sbjct: 430 SASAYLSVEYPAKVTFTPTVQ 450 Score = 62.5 bits (145), Expect = 1e-07 Identities = 92/395 (23%), Positives = 149/395 (37%), Gaps = 55/395 (13%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ++ CQ +G P P+I W++ + PS ++ D + IR ED G +TC Sbjct: 268 GDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRH---EDIGEYTC 324 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A+N G S T +I+ G + + +PPT K Sbjct: 325 IARNGEGQVSHTARVIIA------GGAVIM------------------VPPTNQTKL--- 357 Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEI--VPDENISVAIESDMHMYCSVLKITNV 700 EG ++ C A+P + W +G + V V I D L I + Sbjct: 358 ---EGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKD-----GSLIINPI 409 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 K G Y N G+ P + P +V + + ++ + Sbjct: 410 KPDDSGQYLCEVTNGIGD---PQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKS 466 Query: 761 NPR-PTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSA 818 +P+ +TW K+ + ++ K + ++L + + +G Y N++G A S Sbjct: 467 SPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASG 526 Query: 819 V--ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNEIISP 875 V + V +P EP R +V E L A T P+I W R E ++ Sbjct: 527 VMDVLVRKPPAFTVEPETLYQRKVGDSV-EMHCDALEAEGTER--PTIKWQRQEGEQLTE 583 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 S+ G NI I N+ E D G Y+CV SN Sbjct: 584 SQRNRIKISGGNI--TIENLRRE-DFGYYQCVVSN 615 Score = 42.7 bits (96), Expect = 0.11 Identities = 123/643 (19%), Positives = 237/643 (36%), Gaps = 66/643 (10%) Query: 1284 VEFP-----PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSI 1338 VEFP P ++ ++++ + GSD+ + + Y+++P+ +E K + ++ S Sbjct: 152 VEFPNDHPVPYVLQWDKKVS-ETGSDLPIYIWYESYPEHIEEGY-------KGRVSRVSQ 203 Query: 1339 DSK--SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI--LDKPSPPG----KPNIL 1390 DS SASL + + +D G Y+ ++ N T LD +PP +I+ Sbjct: 204 DSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDII 263 Query: 1391 EIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 ++ I + + T I++Y + +D + + + N T+ I ++ Sbjct: 264 YVNLGDSIILNCQADGTPTPEILWYK-DANPVDPSPTVGIFN-DGTELRISTIRHEDIGE 321 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP- 1509 + A N + + +VI + P N T E + +C +P Sbjct: 322 YTCIARN-----GEGQVSHTARVIIAG---GAVIMVPPTNQTKLEGEKVIFSCEAKAMPG 373 Query: 1510 QPKVTWYRDGKKLKTAKA-----TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-SC 1563 V WYR+G ++ A T Y C N G+ ++ S Sbjct: 374 NVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASA 433 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE-VIWYKNGNKLENDKEYNIT 1622 + ++ +T + ++ +V I+ P + V W K+ LE + +I Sbjct: 434 YLSVEYPAKVTFTPTVQYLPFRLAG--VVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIV 491 Query: 1623 TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-DKPS----KPEGPVIMRE 1677 S++ + H +Y N GT+ + V KP +PE + R+ Sbjct: 492 VMANGSLL-FTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPE-TLYQRK 549 Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 + +SV + L+ G E ++ E + + + I+ L Sbjct: 550 VG-DSVEMHCDA-LEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFG 607 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGS 1797 ++ + N V A+ ++ ++ T P S+ + W P G Sbjct: 608 YYQCVVSNEVATLMAV-TQLVIEGTQPHAPYNITGKAT-----ESSITLQWLPGYSGGSE 661 Query: 1798 PIIDYKVEIKQEG-KKWKXXXXXXXXXAR--IQKLSINTTYQFRIYARNEIGTSLPYTSD 1854 DY + ++ G W+ + I L+ TTY+F++ RN +G + Sbjct: 662 YKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMM---- 717 Query: 1855 DKITIGKTL-TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 K+ +TL P+ PRN V +T + P+ G P Sbjct: 718 SKVMTVRTLEDAPAAPRN--VKAATQPPDSFFQLMPDEAGPKP 758 Score = 40.3 bits (90), Expect = 0.57 Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%) Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI-VTVGGSV 1922 T P P N + ++T S+TL+W S G +Y I F+ W I VT GS Sbjct: 631 TQPHAPYN-ITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGST 689 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR 1976 + I + F++ N +G + ++ +VR T+ P AP ++ Sbjct: 690 -QVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVR-----TLEDAPAAPRNVK 737 Score = 36.7 bits (81), Expect = 7.0 Identities = 20/83 (24%), Positives = 38/83 (45%), Gaps = 2/83 (2%) Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G V F C+ + P + W+R+ + ++ + +L+I + P+D+G + Sbjct: 358 EGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQY 417 Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603 C N G S++ L VE P Sbjct: 418 LCEVTNGIGDPQSASAYLSVEYP 440 Score = 36.7 bits (81), Expect = 7.0 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 7/82 (8%) Query: 524 GSTVQFEC---QVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLVIREVFPEDAG 579 G +V+ C + EG RP I W RQ + SQ ++ N+ +R ED G Sbjct: 551 GDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRR---EDFG 607 Query: 580 TFTCVAKNAAGFASSTTELIVE 601 + CV N + T+L++E Sbjct: 608 YYQCVVSNEVATLMAVTQLVIE 629 >UniRef50_O15394 Cluster: Neural cell adhesion molecule 2 precursor; n=35; Tetrapoda|Rep: Neural cell adhesion molecule 2 precursor - Homo sapiens (Human) Length = 837 Score = 97.9 bits (233), Expect = 3e-18 Identities = 138/660 (20%), Positives = 256/660 (38%), Gaps = 45/660 (6%) Query: 1215 YLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 + T E + WY + I T++ + + L I +D Y C DA Sbjct: 39 FFTCTAIGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDA 98 Query: 1274 KSTTKLKVEVVEFPPKIVDYE--REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 K T+ V+E K+ E K+G D ++ + P P W+ +++ + Sbjct: 99 KGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTI 158 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKL--RLENNCGHADVEMNVTILDKPSPPGKP-- 1387 + ++ + + +L I + +D GIY+ R+E G D + I++ P P Sbjct: 159 SDNRLAMLANN-NLQILNINKSDEGIYRCEGRVEAR-GEIDFRDIIVIVNVPPAISMPQK 216 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 + + + + I + + I+ E +K + T+ +++N+ + Sbjct: 217 SFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKG-SNTELTVRNIINSD 275 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + A N+ + E + +V +Q ++ LKN TT N + L C G Sbjct: 276 GGPYVCRATNK---AGEDEKQAFLQVF----VQPHIIQ--LKNETTYENGQVTLVCDAEG 326 Query: 1508 VPQPKVTWYR--------DGKKLKTAKATYENRXXXXXXXXXX---XXXXXYKCIAFNDH 1556 P P++TW R +G K + + + Y C A + Sbjct: 327 EPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRI 386 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G + S + I+ P ISN+ I + G+ ++ ++ PP + W ++ L Sbjct: 387 GGHQKSMYLDIEYAPKF-ISNQTIYYSWE-GNPINISCDVKSNPPASIHWRRDKLVLPAK 444 Query: 1617 KEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 N+ T + ++ I + +Y A+N GT E L + D PS P G I Sbjct: 445 NTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKI 504 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI-QKLNE 1733 + E+S+ + + + P GG+ + Y ++ E + W V V+T + L Sbjct: 505 I-ELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVR--SHGVQTMVVLNNLEP 561 Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 N Y RV A N G + + E I + PS + + IT + Sbjct: 562 NTTYEIRVAAVNGKGQGDYSKIE-IFQTLPVREPSPPSIHGQPSSGKSFKLSIT---KQD 617 Query: 1794 NGGSPIIDYKVEIKQEGK--KW-KXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 +GG+PI++Y V+ + + K +W + ++ L +FR+ A N +G S P Sbjct: 618 DGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGMKFRLPAANRLGYSEP 677 Score = 88.6 bits (210), Expect = 2e-15 Identities = 116/562 (20%), Positives = 224/562 (39%), Gaps = 46/562 (8%) Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXX-DVGVIKCIVKD-----QETSTML 1010 S WY+ + E R ++Q+G D G+ +C D QE + +L Sbjct: 50 SIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVL 109 Query: 1011 VVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-W-ERDGEIIKPKKNKYDFEKR 1068 + + + F + E K+ + A + ++S A V W + E+ N+ Sbjct: 110 EIYQKLT-FREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLAN 168 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDES-----CTAEVTVVELPPEIITRLQ--NQKVNKG 1121 +++ I N + DEG Y C R E+ + +V +PP I + N +G Sbjct: 169 NNLQ---ILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERG 225 Query: 1122 NKATFEIELTKG-DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC-- 1178 + TF + + + WF++G I+ + + + G +L + + D G Y C Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLIEENE--KYILKGSNTELTVRNIINSDGGPYVCRA 283 Query: 1179 --EVGNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-DVTWYKKKS 1234 + G + A L V +P I ++L N L + E + ++TW + Sbjct: 284 TNKAGEDEKQAFLQVFVQPHI---IQLKNETTYE-NGQVTLVCDAEGEPIPEITWKRAVD 339 Query: 1235 VIEDTE-------KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEF 1286 TE + + +L I+ Y C + + + +E+ Sbjct: 340 GFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKSMYLDIEY 399 Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT---KPSIDSKSA 1343 PK + + Y G+ + + D ++ P + W K++ K+T K + Sbjct: 400 APKFISNQTIYYSWEGNPINISCDVKSNPPASIHWR-RDKLVLPAKNTTNLKTYSTGRKM 458 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 L I + D G Y N+ G E + + D PS P I+E+ ++ + +++ Sbjct: 459 ILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNK 518 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDIS 1462 P++ G I +Y V+ +E+ + W V++ +T + NL+ N++Y R AVN Sbjct: 519 PDSHGGVPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQG 578 Query: 1463 DASETTEYYKVIKETKIQSPTV 1484 D S+ E ++ + + P++ Sbjct: 579 DYSK-IEIFQTLPVREPSPPSI 599 Score = 85.4 bits (202), Expect = 2e-14 Identities = 85/342 (24%), Positives = 140/342 (40%), Gaps = 31/342 (9%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 TF + Q +G D + CR+ + P P ++WL+ EE+ + +A+ ++ + Sbjct: 116 TFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNN----- 170 Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSM--IVRQGES 751 L+I N+ K EG Y V GE ++ I PP + P KS +GE Sbjct: 171 LQILNINKSDEGIYRCEGRVEARGEIDFRDIIVI---VNVPPAISMPQKSFNATAERGEE 227 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + S + G+P P I+W +N K ++ +++ ++ D G Y +A N Sbjct: 228 MTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKA 287 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G E A + V +P I + + T E G + LV P+P ITW R + Sbjct: 288 GEDEKQAFLQV------FVQP--HIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVD 339 Query: 872 II-------SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 SP I + L I +V SG Y C A++ G H + +D Sbjct: 340 GFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLS-GSGRYDCEAASRIG--GHQKSMYLD 396 Query: 925 VEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNK 964 +E Q Y + EG + + C +++ S W +K Sbjct: 397 IEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDK 438 Score = 72.5 bits (170), Expect = 1e-10 Identities = 95/471 (20%), Positives = 182/471 (38%), Gaps = 37/471 (7%) Query: 736 QVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSITI 791 QV L + + GES + +G PR +I W N + K + T+ G S Sbjct: 22 QVTISLSKVELSVGESKFFTCTAIGEPR-SIDWY-NPQGEKIISTQRVVVQKGGVRSRLT 79 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIK 851 + ++D G+Y +A +++G + + V+ E + F K+ + Sbjct: 80 IYNANIEDAGIYRCQATDAKGQTQEATVVL------EIYQKLTFREVVSPQEFKQGEDAE 133 Query: 852 LVARVTRNPVPSITW-YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 +V RV+ +P P+++W Y N E+ + S+ N++++ N + D G Y+C Sbjct: 134 VVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNIN---KSDEGIYRCEGRV 190 Query: 911 SAGKSSHGARVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSHTV--STKWYHNKKE 966 A + + V + QKS+ E G+ + C+ S + + W+ N K Sbjct: 191 EARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKL 250 Query: 967 ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ--ETSTMLVVKETIPEFIRKLQ 1024 I ++ + I +G D G C ++ E ++ + I +L+ Sbjct: 251 IE--ENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLK 308 Query: 1025 DFEVKEKDVAILEVEINSETA-DVVWER--DG----EIIKPKKNKYDFEKRGHIRKLYIR 1077 + E L + E ++ W+R DG E K + + + + L+I+ Sbjct: 309 NETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIK 368 Query: 1078 NTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134 + + G Y C + ++ +E P+ I+ +GN ++ Sbjct: 369 DVKLSGSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNP 428 Query: 1135 -ALVRWFKDGSEIQFSNHIQLTI--DGKKQKLKIYDCDLDDAGEYSCEVGN 1182 A + W +D + N L G+K L+I +D G Y+C N Sbjct: 429 PASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479 Score = 64.9 bits (151), Expect = 2e-08 Identities = 72/300 (24%), Positives = 117/300 (39%), Gaps = 34/300 (11%) Query: 628 ILEGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 ++ +PP S K+ + G ++ CR PEP I+W G+ I +EN ++ Sbjct: 203 VIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLI--EENEKYILK 260 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + L + N+ G Y A N+ GE L++ P +I+ LK+ Sbjct: 261 GSN----TELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFV----QPHIIQ-LKNET 311 Query: 746 VRQGESVILSAQVVGNPRPTITWCK----------NNKPVKALPTKSDGDTHSITILKPK 795 + V L G P P ITW + + P + K + S+ I K Sbjct: 312 TYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHI-KDV 370 Query: 796 KVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 K+ G Y +A + G + S + +E P FI+ E I + Sbjct: 371 KLSGSGRYDCEAASRIGGHQKSMYLDIEYA-------PKFISNQTIYYSWEGNPINISCD 423 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV--DSEIDSGDYKCVASNSAG 913 V NP SI W R ++++ P++ T +I + S+ D G Y C A+N G Sbjct: 424 VKSNPPASIHW-RRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482 Score = 61.7 bits (143), Expect = 2e-07 Identities = 52/189 (27%), Positives = 81/189 (42%), Gaps = 9/189 (4%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 PS P + E + + + + +P+S+GG PI +Y ++ K V + W KIV G Sbjct: 496 PSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIW-KIVRSHGVQTMV 554 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-MVGSNIVM 1984 + N++ R++A N G + ++E T+P +P I S Sbjct: 555 VLNNLEPNTTYEIRVAAVNGKG-----QGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSF 609 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTK-TMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 T + DGGAP+L Y + R K W+E KV N + L R+ A Sbjct: 610 KLSITKQDDGGAPILEYIVKYRSKDKEDQWLE-KKVQGNKDHIILEHLQWTMGMKFRLPA 668 Query: 2044 RNEIGLSEP 2052 N +G SEP Sbjct: 669 ANRLGYSEP 677 Score = 59.7 bits (138), Expect = 9e-07 Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 21/288 (7%) Query: 1108 EIITRLQNQKVNKGNKATFEIELTKGDALVRWFK-DGSEIQFSNHIQLTIDGKKQKLKIY 1166 ++ L +++ G F + W+ G +I + + + G + +L IY Sbjct: 22 QVTISLSKVELSVGESKFFTCTAIGEPRSIDWYNPQGEKIISTQRVVVQKGGVRSRLTIY 81 Query: 1167 DCDLDDAGEYSCEVGNSK-----CTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEI 1220 + +++DAG Y C+ ++K T +L + ++ + + EF DA + + Sbjct: 82 NANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEF---KQGEDAEVVCRV 138 Query: 1221 PDETLD-VTW-YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-LLDAKSTT 1277 V+W Y + V T ++ + L I + D+ Y C ++A+ Sbjct: 139 SSSPAPAVSWLYHNEEV--TTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEI 196 Query: 1278 KLK--VEVVEFPPKIVDYEREYR--IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + + +V PP I ++ + +RG ++T P+P W N K+I+ ++ Sbjct: 197 DFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIE--EN 254 Query: 1334 TKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 K + + LT++ + N+D G Y R N G + + + + +P Sbjct: 255 EKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQP 302 Score = 45.6 bits (103), Expect = 0.015 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 3/67 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + F C+ G P P I+WFR +I ++ + Y + L +R + D G + C Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLI---EENEKYILKGSNTELTVRNIINSDGGPYVC 281 Query: 584 VAKNAAG 590 A N AG Sbjct: 282 RATNKAG 288 >UniRef50_P13591 Cluster: Neural cell adhesion molecule 1, 140 kDa isoform precursor; n=109; Euteleostomi|Rep: Neural cell adhesion molecule 1, 140 kDa isoform precursor - Homo sapiens (Human) Length = 848 Score = 97.9 bits (233), Expect = 3e-18 Identities = 140/691 (20%), Positives = 269/691 (38%), Gaps = 60/691 (8%) Query: 1101 TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI---D 1157 T V L +I+ V + ++ D + WF E N ++++ D Sbjct: 16 TAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWND 75 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEV---GNSKCTAILTVEEPSINFTLRLPEFILVPANTDA 1214 L IY+ ++DDAG Y C V S+ A + V+ P DA Sbjct: 76 DSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDA 135 Query: 1215 YLTVEIPDETLDVTWYKKKS---VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTC--- 1268 + ++ +K K +++ +F ++S+ L IR + D+ Y C Sbjct: 136 VIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSN---NYLQIRGIKKTDEGTYRCEGR 192 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYER--EYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 +L + K +V PP I + G VTL+ D + FP+P W + + Sbjct: 193 ILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGE 252 Query: 1327 IIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 I++ + + I S +S LTIKKV+ D Y EN G D +++ + KP Sbjct: 253 QIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY 312 Query: 1386 KPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNITKTQTSIQ- 1441 N +E++ C E +G+ I + W S +NI+ + ++ Sbjct: 313 VENQTAMELEEQVTLTC----EASGD-----------PIPSITWRTSTRNISSEEKTLDG 357 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASE--TTEYYKVIKET-----KIQ-SPTVEKPLKNITT 1493 ++ S R + + + +DA E T + +++ ++Q +P ++ P+ T Sbjct: 358 HMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW 417 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT----YENRXXXXXXXX--XXXXXXX 1547 E N+ + +TC P ++W+RDG+ L ++ + Y Sbjct: 418 EGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476 Query: 1548 YKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGD-EWLVTAVIEGIP--PPEV 1604 Y C A N G+ ++ +Q + S + ++ ++ G+P + Sbjct: 477 YNCTAVNRIGQESLEFIL-VQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKA 535 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 W G ++ + K Y+ ++ I LK + + A N G + + Sbjct: 536 EWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 595 Query: 1665 KP--SKPEGPVIMREISRESVTIEWK-PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 +P +P P + ++ + +I+ DDGG + Y + ++ ++ W + Sbjct: 596 QPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLV-RYRALSSEWKPEIRLPS 654 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 + ++ L+ N EY V+A+N G S+A Sbjct: 655 GSDHVMLKSLDWNAEYEVYVVAENQQGKSKA 685 Score = 89.8 bits (213), Expect = 7e-16 Identities = 130/655 (19%), Positives = 241/655 (36%), Gaps = 54/655 (8%) Query: 1226 DVTWYKK--KSVIEDTEKFTLI-SDVKKRTLIIRKCTEDDQCEYTCVLL-DAKSTTKLKV 1281 D++W+ + + + ++ +++ +D TL I DD Y CV+ + S ++ V Sbjct: 51 DISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATV 110 Query: 1282 EVVEFPPKIV-DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V F + + + G D ++ D + P W + + K + + S Sbjct: 111 NVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLS 170 Query: 1341 KSASLTIKKVENTDAGIYK----LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS- 1395 + L I+ ++ TD G Y+ + D+++ V + P+ + NI+ ++ Sbjct: 171 NNY-LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNV--PPTIQARQNIVNATANL 227 Query: 1396 --SINICWDE---PENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYR 1450 S+ + D PE T + T +E QE D ++I + +Q +I+ + N Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIE-QEEDDEKYIFSDD--SSQLTIKKVDKNDEAE 284 Query: 1451 FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQ 1510 + A N+ DA+ + + K T +++ T E E + LTC G P Sbjct: 285 YICIAENKAGEQDATIHLKVFAKPKITYVENQTA--------MELEEQVTLTCEASGDPI 336 Query: 1511 PKVTWYRDGKKLKTAKATYENR---------XXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 P +TW + + + + T + Y C A N G+ Sbjct: 337 PSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQ 396 Query: 1562 SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNI 1621 S + +Q P + + G++ +T + P + W+++G L + NI Sbjct: 397 SMYLEVQYAPKL---QGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453 Query: 1622 T--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREIS 1679 S + + + Y A N G S+E L D PS P + E Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPS--IDQVEPY 511 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIE----KHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 + +++ P GG+ + KY E E +++W + + I L Sbjct: 512 SSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME-GIVTIVGLKPET 570 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 Y R+ A N G E + + PS D S+ + + +G Sbjct: 571 TYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGE-DGNSIKVNLI-KQDDG 628 Query: 1796 GSPIIDYKVEIKQEGKKWK--XXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 GSPI Y V + +WK ++ L N Y+ + A N+ G S Sbjct: 629 GSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKS 683 Score = 89.0 bits (211), Expect = 1e-15 Identities = 93/398 (23%), Positives = 166/398 (41%), Gaps = 36/398 (9%) Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDIL 652 SS+T I A + D G V ++ F P Q EG D + Sbjct: 77 SSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAV 136 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 + C +V+ P I W KG +++ +++ + S+ + L+I +KK EGTY Sbjct: 137 IVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSN-----NYLQIRGIKKTDEGTYRCEG 191 Query: 713 -VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKN 771 + GE + + ++ Q + + + G+SV L G P PT++W K+ Sbjct: 192 RILARGEINFKDI-QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKD 250 Query: 772 NKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 + ++ D+ +TI K K DE Y AEN G E A I + + Sbjct: 251 GEQIEQEEDDEKYIFSDDSSQLTIKKVDK-NDEAEYICIAENKAG--EQDATIHL----K 303 Query: 828 ENAEPPL-FINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 A+P + ++ + ++E+ + L + +P+PSITW + IS E + DG Sbjct: 304 VFAKPKITYVENQTAMELEEQ--VTLTCEASGDPIPSITWRTSTRNISSEE---KTLDGH 358 Query: 887 NIELVITNVDS-------EIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYE 939 + V S D+G+Y C ASN+ G+ S + ++V+ ++ Y Sbjct: 359 MVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQS--MYLEVQYAPKLQGPVAVY- 415 Query: 940 TEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975 T EG V + C+ + + W+ + + + ++ I Sbjct: 416 TWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453 Score = 85.4 bits (202), Expect = 2e-14 Identities = 74/299 (24%), Positives = 126/299 (42%), Gaps = 25/299 (8%) Query: 628 ILEGIPPTFSKKPKA--QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 ++ +PPT + + G + L C PEP ++W GE+I +E+ I Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 SD S L I V K E Y +A N+ GE I LK+ P++ Sbjct: 266 SDDS---SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA----KPKITYVENQTA 318 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGD----TH---SITILKPKKVK 798 + E V L+ + G+P P+ITW + + + + DG +H S LK + Sbjct: 319 MELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYT 378 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G Y A N+ I + S + +E + P+ + + E + + V Sbjct: 379 DAGEYICTASNT--IGQDSQSMYLEVQYAPKLQGPVAVYTW------EGNQVNITCEVFA 430 Query: 859 NPVPSITWYRNNEIISPSE-TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P +I+W+R+ +++ S + + ++ + + DSE D G+Y C A N G+ S Sbjct: 431 YPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQES 489 Score = 73.7 bits (173), Expect = 5e-11 Identities = 112/536 (20%), Positives = 218/536 (40%), Gaps = 51/536 (9%) Query: 1025 DFEVKEKDVAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRK-LYIRNTSVH 1082 + V E + +V +++ D+ W +GE + P + + L I N ++ Sbjct: 30 EISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANID 89 Query: 1083 DEGEYSCILRDESCT-AEVTV-VELPPEIITRLQN--QKVNKGNKATFEIELTKG-DALV 1137 D G Y C++ E + +E TV V++ +++ + Q+ +G A ++ + Sbjct: 90 DAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTI 149 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-------NSKCTAILT 1190 W G ++ ++ + L+I D G Y CE N K ++ Sbjct: 150 IWKHKGRDVILKKDVRFIVLSNNY-LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIV 208 Query: 1191 VEEPSI-------NFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIE---DTE 1240 P+I N T L + + + + + + P+ T+ +W K IE D E Sbjct: 209 NVPPTIQARQNIVNATANLGQSVTLVCDAEGF-----PEPTM--SWTKDGEQIEQEEDDE 261 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRI 1299 K+ D + T I+K ++D+ EY C+ + + + F PKI E + + Sbjct: 262 KYIFSDDSSQLT--IKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAM 319 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-----HTKPSIDSKSASLTIKKVENTD 1354 + VTL + P P+ W +++ I + H ++ +SLT+K ++ TD Sbjct: 320 ELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTD 379 Query: 1355 AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY 1414 AG Y N G M + + P G + + + +NI E ++TI + Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITC-EVFAYPSATISW 438 Query: 1415 YVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 + + Q + ++ + ++K S + +S F Y V+ E+ E+ V Sbjct: 439 F-RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVN-RIGQESLEFILVQ 496 Query: 1475 KETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVP--QPKVTWYRDGKKLKTAK 1526 +T SP+++ +P + ++ E T GGVP + K W G+++ +K Sbjct: 497 ADTP-SSPSIDQVEPYSSTAQVQFDEPEAT---GGVPILKYKAEWRAVGEEVWHSK 548 Score = 54.4 bits (125), Expect = 3e-05 Identities = 25/79 (31%), Positives = 41/79 (51%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +V C EG+P P ++W + I+ +D + Y D+ + L I++V D + C Sbjct: 228 GQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYIC 287 Query: 584 VAKNAAGFASSTTELIVEA 602 +A+N AG +T L V A Sbjct: 288 IAENKAGEQDATIHLKVFA 306 Score = 48.0 bits (109), Expect = 0.003 Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 5/106 (4%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P A Y EG+ + + C + A P I+W F+ +++P N S I+ S L++T Sbjct: 411 PVAVYTWEGNQVNITCEVFAYPSATISW-FRDGQLLPSSNYS-NIKIYNTPSASYLEVTP 468 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV--IEPLKS 743 + G Y AVNR G+ SL +L ++ P + +EP S Sbjct: 469 DSENDFGNYNCTAVNRIGQESLEFIL-VQADTPSSPSIDQVEPYSS 513 Score = 45.6 bits (103), Expect = 0.015 Identities = 44/189 (23%), Positives = 85/189 (44%), Gaps = 7/189 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHE 1924 PS P V E S + +++ EPE+ GG PI Y E++ V + W +K + E Sbjct: 500 PSSPSIDQV-EPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASME 558 Query: 1925 HCIENIKEKDEIIF--RISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 + + K E + R++A N G+ + + + + PS P ++ G++I Sbjct: 559 GIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSI 618 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 + + DGG+P+ Y + R ++ + W ++ + ++ L N Y + + Sbjct: 619 KVNL--IKQDDGGSPIRHYLVRYRALS-SEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVV 675 Query: 2043 ARNEIGLSE 2051 A N+ G S+ Sbjct: 676 AENQQGKSK 684 Score = 41.1 bits (92), Expect = 0.33 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Query: 520 HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ--MYYDDDNVATLVIREVFPED 577 +T +G+ V C+V YP I+WFR ++ PS ++ Y+ + + L + D Sbjct: 415 YTWEGNQVNITCEVFAYPSATISWFRDGQLL-PSSNYSNIKIYNTPSASYLEVTPDSEND 473 Query: 578 AGTFTCVAKNAAGFASSTTELIVEA 602 G + C A N G S ++V+A Sbjct: 474 FGNYNCTAVNRIG-QESLEFILVQA 497 Score = 40.7 bits (91), Expect = 0.43 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 3/131 (2%) Query: 524 GSTVQFECQVEGYPRPQ-ITWFRQTAI-IKPSQD-FQMYYDDDNVATLVIREVFPEDAGT 580 G + F CQV G + + I+WF + P+Q + ++DD+ +TL I +DAG Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGI 93 Query: 581 FTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP 640 + CV G S T + + T D++ +PPT K Sbjct: 94 YKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKH 153 Query: 641 KAQYVDEGSDI 651 K + V D+ Sbjct: 154 KGRDVILKKDV 164 Score = 36.7 bits (81), Expect = 7.0 Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQ---DFQMYYDDD-NVATLVIREVFPEDAGTFT 582 V C+ G P P ITW T I + D M V++L ++ + DAG + Sbjct: 325 VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 384 Query: 583 CVAKNAAGFASSTTELIVE 601 C A N G S + L V+ Sbjct: 385 CTASNTIGQDSQSMYLEVQ 403 >UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 protein tyrosine kinase 7 isoform a precursor; n=1; Apis mellifera|Rep: PREDICTED: similar to PTK7 protein tyrosine kinase 7 isoform a precursor - Apis mellifera Length = 1112 Score = 97.5 bits (232), Expect = 4e-18 Identities = 145/666 (21%), Positives = 269/666 (40%), Gaps = 57/666 (8%) Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 V +G V L + + R W + +P+ P + D + I + ++ D G + Sbjct: 38 VAEGSPVRLRCEAQPSSRVKYMWKIDGQPLAPSPRRHQ-DGGDLRITRVNRILDSGNFVC 96 Query: 806 KAENSE-GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A + E G + S+ ++ A L + ++ G I+L V + Sbjct: 97 VATHEETGYSIESSPAKIDIQWISEASVQLQQPKLPS-AIRVGGEIELRCHVDGSGDIKY 155 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS--HGARVT 922 W+RN E ++ S+ I + + +L + +E DSG Y C+A N AG S + Sbjct: 156 EWFRNREPVARSDRI----EIKKKKLHVHRAVAE-DSGMYNCLAKNDAGSSPKMESFPLI 210 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKK-EISGMDHREIIQEGRX 981 + + VK + + + G+ +L C S +W+ + D R + + G Sbjct: 211 VSSNETASVKVVPRDLIAKRGEPAVLHCVFEDADSVQWFFKDMGPLETDDERTVFENG-- 268 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQ--DFE-VKEKDVAILEV 1038 D G C D+ ST+ + ++ L FE + VA++ Sbjct: 269 -TLVIRSAEHRDQGFYSCH-GDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGE 326 Query: 1039 EINSETADVVWERDGEIIKPKKNKYDFEKRGHI-----------RKLYIRNTSV-HDEGE 1086 E + + + E G P Y + +GHI L + + D+G Sbjct: 327 EQELQVSCL--EPSG---LPPPRVYWRDPKGHIISDSGPVRVQDNTLIVAKARMGEDDGN 381 Query: 1087 YSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDALV---RWF 1140 Y+C+ + + +++ V+ PP +I+ +N V +G+ T + DA V RW Sbjct: 382 YTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWL 441 Query: 1141 KDGSEIQFSN---HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 KDG ++ S ++T L + DL D G Y+CE+ I + E + Sbjct: 442 KDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFS-ERAGLT 500 Query: 1198 FTLRLPEFILVPANTDAYL--TVEIPDETLDVTWYKKKSVIEDT-EKFTL-ISDVKKRTL 1253 +L +F P + L T ++P ++ T K + E + E+F + D+ TL Sbjct: 501 VEEKL-KFSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGSGEEFPKHVQDING-TL 558 Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTK--LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 E+D+ YTC+ +A+ + + ++VV P + + G V L Sbjct: 559 HFNGVLEEDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAA 618 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG--HA 1369 + P+P +W +S+ + +++ + + SL IK+V +D G Y N+ G Sbjct: 619 EGDPKPTIQWDRDSR-MNNLNNSRFEV-LGNGSLYIKEVYMSDEGKYGCTAGNSGGLKRE 676 Query: 1370 DVEMNV 1375 +V++NV Sbjct: 677 EVQLNV 682 Score = 76.6 bits (180), Expect = 7e-12 Identities = 132/657 (20%), Positives = 244/657 (37%), Gaps = 59/657 (8%) Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE------- 1094 S +W+ DG+ + P ++ + G +R R + D G + C+ E Sbjct: 53 SSRVKYMWKIDGQPLAPSPRRH--QDGGDLR--ITRVNRILDSGNFVCVATHEETGYSIE 108 Query: 1095 SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-----KGDALVRWFKDGSEIQFS 1149 S A++ + + E +LQ K+ + EIEL GD WF++ + S Sbjct: 109 SSPAKIDIQWIS-EASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNREPVARS 167 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS-KCTAILTVEEPSINFTLRL-P 1203 + I++ KK+KL ++ +D+G Y+C + G+S K + + + ++++ P Sbjct: 168 DRIEI----KKKKLHVHRAVAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVP 223 Query: 1204 EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQ 1263 ++ A L D ++K +E ++ T+ + TL+IR DQ Sbjct: 224 RDLIAKRGEPAVLHCVFEDADSVQWFFKDMGPLETDDERTVFEN---GTLVIRSAEHRDQ 280 Query: 1264 CEYTC----------VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 Y+C +D + + + F P + ++ V+ L + Sbjct: 281 GFYSCHGDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSCL-EPSG 339 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P P W I + P + + K D G Y EN G D+ Sbjct: 340 LPPPRVYWRDPKGHI--ISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETDISA 397 Query: 1374 NVTILDKPSPPGKP-NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN 1432 V I P+ P N+ ++ S+ + T + ++ + + + + + Sbjct: 398 QVVISTPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPLKESGGPTRHR 457 Query: 1433 ITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQ-SPT-VEKPLK 1489 +T ++ +LK+ YA +E + E K++ SP V+K L Sbjct: 458 VTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFSERAGLTVEEKLKFSPQPVDKRL- 516 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYK 1549 E ++ C G P V W ++G + K + Y Sbjct: 517 ----ELGSTAKVPCKSQGATNPTVKWIKEGSGEEFPKHVQDINGTLHFNGVLEEDKGRYT 572 Query: 1550 CIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKN 1609 CIA N G + + + + P TI ++ + + G ++ EG P P + W ++ Sbjct: 573 CIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIE-GYPVMLHCAAEGDPKPTIQWDRD 631 Query: 1610 G--NKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD 1664 N L N + + + + IKE+ S KY A N+ G EV L V D Sbjct: 632 SRMNNLNNSR-FEVLGNGS---LYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVKD 684 Score = 70.1 bits (164), Expect = 6e-10 Identities = 128/606 (21%), Positives = 231/606 (38%), Gaps = 62/606 (10%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 FS P V EGS + L C W G+ + P H L Sbjct: 29 FSVSPGEHSVAEGSPVRLRCEAQPSSRVKYMWKIDGQPLAPSPR--------RHQDGGDL 80 Query: 696 KITNVKK-FQEGTYTVVAVNREGEASL---PIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 +IT V + G + VA + E S+ P + I+ + Q+ +P +R G Sbjct: 81 RITRVNRILDSGNFVCVATHEETGYSIESSPAKIDIQWISEASVQLQQPKLPSAIRVGGE 140 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + L V G+ W +N +PV A + + + + + +D G+Y A+N Sbjct: 141 IELRCHVDGSGDIKYEWFRNREPV-ARSDRIEIKKKKLHVHR-AVAEDSGMYNCLAKNDA 198 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G + + + E A + + ++G V S+ W+ + Sbjct: 199 GSSPKMESFPLIVSSNETAS----VKVVPRDLIAKRGE-PAVLHCVFEDADSVQWFFKD- 252 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI----DVEK 927 + P ET + EN LVI + + D G Y C S+ + I ++ Sbjct: 253 -MGPLETDDERTVFENGTLVIRSAEHR-DQGFYSCHGDRGESTISYTVDLQIAYLMNLSA 310 Query: 928 VTFVKHLQKSY----ETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXX 983 +F L E +E + LE W K I +Q+ Sbjct: 311 ASFEPLLSSQVAVVGEEQELQVSCLEPSGLPPPRVYWRDPKGHIISDSGPVRVQDN--TL 368 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTML---VVKETIPEFIRKLQDFEVKEKDVAILEVEI 1040 D G C+ ++ T + VV T P I ++ V E D + Sbjct: 369 IVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTCSY 428 Query: 1041 NSETADVV---WERDGEIIK----PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 + A V W +DGE +K P +++ + G++ L++++ + D+G Y+C + Sbjct: 429 SGMDAPVTHVRWLKDGEPLKESGGPTRHRVT-DHHGNV-TLHLKSADLSDKGGYACEITT 486 Query: 1094 E------SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKDGSE 1145 + S A +TV E + + ++++ G+ A + ++G + V+W K+GS Sbjct: 487 KGFPPIFSERAGLTVEE-KLKFSPQPVDKRLELGSTAKVPCK-SQGATNPTVKWIKEGSG 544 Query: 1146 IQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEF 1205 +F H+Q I+G + + +D G Y+C N++ + T+ SI+ + P+F Sbjct: 545 EEFPKHVQ-DINGTLHFNGVLE---EDKGRYTCIASNAQGSINHTI---SIDVVI-APKF 596 Query: 1206 ILVPAN 1211 + P N Sbjct: 597 TIQPQN 602 Score = 68.1 bits (159), Expect = 2e-09 Identities = 67/255 (26%), Positives = 111/255 (43%), Gaps = 26/255 (10%) Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 +G YT VA N GE + + I T PP +I +++ V +G+SV ++ G P Sbjct: 379 DGNYTCVAENMAGETDISAQVVIST----PPTLISSPENLSVMEGDSVTMTCSYSGMDAP 434 Query: 765 T--ITWCKNNKPVKAL--PTKSDGDTH--SITI-LKPKKVKDEGVYT--LKAENSEGIAE 815 + W K+ +P+K PT+ H ++T+ LK + D+G Y + + I Sbjct: 435 VTHVRWLKDGEPLKESGGPTRHRVTDHHGNVTLHLKSADLSDKGGYACEITTKGFPPIFS 494 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISP 875 A +TVEE + + +P +++ E+ T K+ + P++ W + Sbjct: 495 ERAGLTVEEKLKFSPQP---VDKRLELG----STAKVPCKSQGATNPTVKWIKEGS---- 543 Query: 876 SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQ 935 E ++ N L V E D G Y C+ASN+ G +H + + V F Q Sbjct: 544 GEEFPKHVQDINGTLHFNGVLEE-DKGRYTCIASNAQGSINHTISIDV-VIAPKFTIQPQ 601 Query: 936 KSYETEEGKTVILEC 950 E EG V+L C Sbjct: 602 NPTEAIEGYPVMLHC 616 Score = 65.3 bits (152), Expect = 2e-08 Identities = 103/513 (20%), Positives = 188/513 (36%), Gaps = 41/513 (7%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P+ G +L C V + W FK + ++ E+ L I + Sbjct: 223 PRDLIAKRGEPAVLHC--VFEDADSVQWFFKDMGPLETDDERTVFEN------GTLVIRS 274 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQV 758 + +G Y+ E S + L+I EPL S + GE L Sbjct: 275 AEHRDQGFYSCHGDRGESTISYTVDLQIAYLMNLSAASFEPLLSSQVAVVGEEQELQVSC 334 Query: 759 V---GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 + G P P + W + + +++ + K + +D+G YT AEN G + Sbjct: 335 LEPSGLPPPRVYWRDPKGHIISDSGPVRVQDNTLIVAKARMGEDDGNYTCVAENMAGETD 394 Query: 816 TSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN--PVPSITWYRNNEII 873 SA + + + PP I+ + ++V E ++ + + PV + W ++ E + Sbjct: 395 ISAQVVI-------STPPTLISSPENLSVMEGDSVTMTCSYSGMDAPVTHVRWLKDGEPL 447 Query: 874 SPSETITQNFDGE---NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 S T++ + N+ L + + D D G Y C + R + VE+ Sbjct: 448 KESGGPTRHRVTDHHGNVTLHLKSADLS-DKGGYACEITTKGFPPIFSERAGLTVEEKLK 506 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 E G T + C++ + KW KE SG + + +Q+ Sbjct: 507 FSPQPVDKRLELGSTAKVPCKSQGATNPTVKWI---KEGSGEEFPKHVQDINGTLHFNGV 563 Query: 989 XXXXDVGVIKCIVKDQETS---TMLVVKETIPEF-IRKLQDFEVKEKDVAILEVEINSET 1044 D G CI + + S T+ + P+F I+ E E +L + Sbjct: 564 LEE-DKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAIEGYPVMLHCAAEGDP 622 Query: 1045 ADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES--CTAEVT 1101 + W+RD + ++++ G LYI+ + DEG+Y C + EV Sbjct: 623 KPTIQWDRDSRMNNLNNSRFEVLGNG---SLYIKEVYMSDEGKYGCTAGNSGGLKREEVQ 679 Query: 1102 VVELPPEIITRLQNQKVNKGNKATFEIELTKGD 1134 + + R+ + G+ F+++L GD Sbjct: 680 LNVKDTSVDERVNHLSSTAGDTYRFDMDLEVGD 712 Score = 54.0 bits (124), Expect = 4e-05 Identities = 42/189 (22%), Positives = 83/189 (43%), Gaps = 11/189 (5%) Query: 636 FSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 FS +P + ++ GS + C+ P + W+ +G E ++ D++ L Sbjct: 507 FSPQPVDKRLELGSTAKVPCKSQGATNPTVKWIKEGS----GEEFPKHVQ-DIN---GTL 558 Query: 696 KITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILS 755 V + +G YT +A N +G + I + + K Q P +++ +G V+L Sbjct: 559 HFNGVLEEDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQPQNPTEAI---EGYPVMLH 615 Query: 756 AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAE 815 G+P+PTI W ++++ ++ + + +K + DEG Y A NS G+ Sbjct: 616 CAAEGDPKPTIQWDRDSRMNNLNNSRFEVLGNGSLYIKEVYMSDEGKYGCTAGNSGGLKR 675 Query: 816 TSAVITVEE 824 + V++ Sbjct: 676 EEVQLNVKD 684 Score = 47.2 bits (107), Expect = 0.005 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GST + C+ +G P + W ++ + ++F + D N TL V ED G +TC Sbjct: 519 GSTAKVPCKSQGATNPTVKWIKEGS----GEEFPKHVQDIN-GTLHFNGVLEEDKGRYTC 573 Query: 584 VAKNAAGFASSTTEL-IVEAP 603 +A NA G + T + +V AP Sbjct: 574 IASNAQGSINHTISIDVVIAP 594 Score = 46.0 bits (104), Expect = 0.011 Identities = 71/347 (20%), Positives = 127/347 (36%), Gaps = 21/347 (6%) Query: 596 TELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 T ++ +A + + T A ++ PPT P+ V EG + + C Sbjct: 367 TLIVAKARMGEDDGNYTCVAENMAGETDISAQVVISTPPTLISSPENLSVMEGDSVTMTC 426 Query: 656 RLVAIPEP--DIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 + P + WL GE + + +D H + L + + +G Y + Sbjct: 427 SYSGMDAPVTHVRWLKDGEPLKESGGPTRHRVTDHHGNVT-LHLKSADLSDKGGY-ACEI 484 Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK 773 +G + T E++ +P+ + G + + + G PT+ W K Sbjct: 485 TTKGFPPIFSERAGLTVEEKLKFSPQPVDKRL-ELGSTAKVPCKSQGATNPTVKWIKEGS 543 Query: 774 PVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + D G H +L+ +D+G YT A N++G + I V + + Sbjct: 544 GEEFPKHVQDINGTLHFNGVLE----EDKGRYTCIASNAQGSINHTISIDVVIAPKFTIQ 599 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P N + I E + L +P P+I W R++ + + + + + N L Sbjct: 600 PQ---NPTEAI---EGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNSRFEVLG--NGSLY 651 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTI-DVEKVTFVKHLQKS 937 I V D G Y C A NS G ++ + D V HL + Sbjct: 652 IKEVYMS-DEGKYGCTAGNSGGLKREEVQLNVKDTSVDERVNHLSST 697 Score = 44.0 bits (99), Expect = 0.046 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 4/95 (4%) Query: 508 MAPIF-VEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 +AP F ++ P +G V C EG P+P I W R + + + ++ Sbjct: 592 IAPKFTIQPQNPTEAIEGYPVMLHCAAEGDPKPTIQWDRDSRMNNLNNS---RFEVLGNG 648 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 +L I+EV+ D G + C A N+ G +L V+ Sbjct: 649 SLYIKEVYMSDEGKYGCTAGNSGGLKREEVQLNVK 683 Score = 42.3 bits (95), Expect = 0.14 Identities = 66/298 (22%), Positives = 117/298 (39%), Gaps = 29/298 (9%) Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N GI AV + P F E +V E ++L + W Sbjct: 2 AVNGNGIPRFKAV-NITSPVFGQDGDLYFSVSPGEHSVAEGSPVRLRCEAQPSSRVKYMW 60 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN-SAGKSSHGARVTIDV 925 + + ++PS Q DG ++ IT V+ +DSG++ CVA++ G S + ID+ Sbjct: 61 KIDGQPLAPSPRRHQ--DGGDLR--ITRVNRILDSGNFVCVATHEETGYSIESSPAKIDI 116 Query: 926 EKVTFVK-HLQK---SYETEEGKTVILECQT--SHTVSTKWYHNKKEISGMDHREIIQEG 979 + ++ LQ+ G + L C S + +W+ N++ ++ D EI Sbjct: 117 QWISEASVQLQQPKLPSAIRVGGEIELRCHVDGSGDIKYEWFRNREPVARSDRIEI---- 172 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETST------MLVVKETIPEFIRKL-QDFEVKEKD 1032 + D G+ C+ K+ S+ L+V ++ + +D K + Sbjct: 173 KKKKLHVHRAVAEDSGMYNCLAKNDAGSSPKMESFPLIVSSNETASVKVVPRDLIAKRGE 232 Query: 1033 VAILEVEINSETADVVW-ERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 A+L + + V W +D ++ + FE L IR+ D+G YSC Sbjct: 233 PAVLHC-VFEDADSVQWFFKDMGPLETDDERTVFEN----GTLVIRSAEHRDQGFYSC 285 >UniRef50_Q177W1 Cluster: Factor for adipocyte differentiation; n=2; Culicidae|Rep: Factor for adipocyte differentiation - Aedes aegypti (Yellowfever mosquito) Length = 895 Score = 97.5 bits (232), Expect = 4e-18 Identities = 90/385 (23%), Positives = 161/385 (41%), Gaps = 24/385 (6%) Query: 1611 NKLENDKEY-NITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-P 1666 N L+ Y NI T T V L+R+ + ++ ++A N G S S EV K P Sbjct: 249 NDLDQGYGYKNIYTGPDT-VYECVGLRRATTFQFRVKAENENGVSPFSKEVVFKTLPSCP 307 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 S+P P + +I ++W PP+D GG E+ Y + E + + ++ E Sbjct: 308 SRPTKPQVKGKIHATGFKVKWDPPVDTGGAEINLYHL---EISSGAIYERIYSGKESEA- 363 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 I +L+ Y RV+ + P G S S+ ++ T +VP + + Sbjct: 364 MIDRLSPGTTYQIRVLCEGPGGISAF--SDQSLVTTEPEVPGAPPRPHCNGAPTPYAACL 421 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 W + NGG+P+++Y++E++ K ++ L Y ++ A N IG Sbjct: 422 IWEKPDYNGGAPVLEYEMEVEMTNKSRNSCYRGKDQFCVVKDLRPGEMYTVQVRAINRIG 481 Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKT 1906 ++ + G PP+ P++ + + +T+ W EP N G+PI+ YI++ T Sbjct: 482 AG-GWSEEYSFHAG--AAPPNAPKDLNIILKSPTHLTVIWDEPHCN-GAPISEYILQSST 537 Query: 1907 VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVP 1966 + ++N+ FR+ A N+ G S + + S + T Sbjct: 538 SADHPSPPSTE---ELLFQTLKNLAPFTNYHFRVCAVNSAGSSRYSATFSQK-----TPA 589 Query: 1967 SPPTAP-LEIRMVGSNIVMTSWGTP 1990 +PP P L + + ++ W TP Sbjct: 590 APPNVPVLGQHKITARSILICWETP 614 Score = 84.2 bits (199), Expect = 4e-14 Identities = 89/386 (23%), Positives = 160/386 (41%), Gaps = 24/386 (6%) Query: 1665 KPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVE 1724 +P P+ P ++ ++ S+ + W D+G ++ Y +E N I + + ++ + Sbjct: 118 EPDVPKAPTLIAR-TKNSLQLRWNAAADNGA-HISNYILEYDNGKYNGMIHLIN-SQNWK 174 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + + KL+ + Y+FR+ A N G S S+ + TA + PS + S+ Sbjct: 175 QFTVNKLHPSTSYIFRLAAVNEYGRSGY--SDMVKYNTAGNPPSVPAPPTLQHATAS-SL 231 Query: 1785 YITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 + W ++ S ++ +G +K L TT+QFR+ A NE Sbjct: 232 KLAW---QRRSPSEGFTLQMNDLDQGYGYKNIYTGPDTVYECVGLRRATTFQFRVKAENE 288 Query: 1845 IGTSLPYTSDDKITIGKTLTP-PSQP-RNFVVSESTSRSVTLKWTEPESNGGSPITNYII 1902 G S P++ + + KTL PS+P + V + + +KW P GG+ I Y + Sbjct: 289 NGVS-PFSKE---VVFKTLPSCPSRPTKPQVKGKIHATGFKVKWDPPVDTGGAEINLYHL 344 Query: 1903 EFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 E + G + +I + G E I+ + R+ E G+S ++ V E Sbjct: 345 EISS--GAIYERIYS--GKESEAMIDRLSPGTTYQIRVLCEGPGGISAFSDQSLVTTEPE 400 Query: 1963 ATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVN 2022 VP P P W P+++GGAP+L Y + + K+ D Sbjct: 401 --VPGAPPRPHCNGAPTPYAACLIWEKPDYNGGAPVLEYEMEVEMTNKSRNSCYRGKDQF 458 Query: 2023 TLKFNIRDLSENHTYMIRIYARNEIG 2048 + ++DL Y +++ A N IG Sbjct: 459 CV---VKDLRPGEMYTVQVRAINRIG 481 Score = 39.1 bits (87), Expect = 1.3 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 2/104 (1%) Query: 1380 KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK-TQT 1438 +P P P ++ +S+ + W+ + G + I Y++EY I + N Q Sbjct: 118 EPDVPKAPTLIARTKNSLQLRWNAAADNG-AHISNYILEYDNGKYNGMIHLINSQNWKQF 176 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 ++ L ++SY FR AVNE S S+ +Y + +P Sbjct: 177 TVNKLHPSTSYIFRLAAVNEYGRSGYSDMVKYNTAGNPPSVPAP 220 >UniRef50_Q7Z5N4 Cluster: Protein sidekick-1 precursor; n=62; Euteleostomi|Rep: Protein sidekick-1 precursor - Homo sapiens (Human) Length = 2213 Score = 97.5 bits (232), Expect = 4e-18 Identities = 120/443 (27%), Positives = 178/443 (40%), Gaps = 49/443 (11%) Query: 533 VEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA 592 + YPRPQ+TWFR+ I PS + ++ LVI DAG + A N Sbjct: 215 ITSYPRPQVTWFREGHKIIPSNRIAITLENQ----LVILATTTSDAGAYYVQAVNEKNGE 270 Query: 593 SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGS-DI 651 + T+ I + D G+ T+ PT P + V GS + Sbjct: 271 NKTSPFIHLSIARDVGTPETMA-------------------PTIVVPPGNRSVVAGSSET 311 Query: 652 LLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVV 711 LEC A P D++ +K V I S +H + L I+N G Y Sbjct: 312 TLECIASARPVEDLSVTWKRN--------GVRITSGLHSFGRHLTISNPTSADTGPYVCE 363 Query: 712 AVNREGEASLPIVLKIKTGEKEPPQ-VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCK 770 A G A P EPP EP + E+V + Q +G P PT+ W K Sbjct: 364 AA-LPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYK 422 Query: 771 NNKPVKAL--PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 + + L P + + I K + +D G++ A N G +T + V Sbjct: 423 DAISISRLQNPRYKVLASGGLRIQKLRP-EDSGIFQCFASNEGGEIQTHTYLDVTNIA-- 479 Query: 829 NAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEII-SPSETITQNFDGEN 887 P+F R + TV + T L V+ P P+ITW R N I+ S S I + E+ Sbjct: 480 ----PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLES 535 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 L I V + D+G+Y C A+N+ G S A T+ V T + H + + +G T Sbjct: 536 GGLQIAPVFIQ-DAGNYTCYAANTEG--SLNASATLTVWNRTSIVHPPEDHVVIKGTTAT 592 Query: 948 LECQTSH--TVSTKWYHNKKEIS 968 L C +H VS ++ K ++ Sbjct: 593 LHCGATHDPRVSLRYVWKKDNVA 615 Score = 87.0 bits (206), Expect = 5e-15 Identities = 107/468 (22%), Positives = 180/468 (38%), Gaps = 30/468 (6%) Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG----PVI 1674 Y + ++ I L ++ ++ N G S + +V P V Sbjct: 1122 YEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVT 1181 Query: 1675 MREISRESVTIEWKPPLD---DGGLELTKYAIEKHEPDNNRWIKVADV--DRDVETYCIQ 1729 +R S S+ + W P D +G E Y I+ D VA V DR + I+ Sbjct: 1182 VRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQS-SAVAQVVSDRLEREFTIE 1240 Query: 1730 KLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF 1789 +L E EY ++ A N VG SE + +T VPS + + + +TW Sbjct: 1241 ELEEWMEYELQMQAFNAVGAGPW--SEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWT 1298 Query: 1790 P-SEKNGGSPIIDYKVEIKQEG----KKWKXXXXXXXXXARIQKLSINTTYQFRIYARNE 1844 E++ I+ YK+ + + + A + L Y+ ++ A Sbjct: 1299 SVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTR 1358 Query: 1845 IGTSLPYTSDDKITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE 1903 IG +P T + + +T P P V E SV + W PE G I Y I Sbjct: 1359 IGNGVPSTP---LILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGI-ILGYQIA 1414 Query: 1904 FKTVKGKSWT-KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKH 1962 ++ T V VG +V + ++ + IFR+SA+ G P E+ + EK Sbjct: 1415 YRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKR 1474 Query: 1963 ATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEV-GKVD 2020 P+PP L + V + + W P DG +P+ + + +R++ + W + Sbjct: 1475 ER-PAPPRELLVPQAEVTARSLRLQW-VPGSDGASPIRYFTMQVRELPRGEWQTYSSSIS 1532 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIG---LSEPLESDEPFKVIPGE 2065 + L +Y +R+ A N+IG S E+ + +PGE Sbjct: 1533 HEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGE 1580 Score = 81.8 bits (193), Expect = 2e-13 Identities = 129/541 (23%), Positives = 210/541 (38%), Gaps = 48/541 (8%) Query: 685 ESDMHMYCSVLK--ITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 +S++ Y S K I +++K G Y V NR G A L +++ + K Sbjct: 142 DSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMG-ALLQRKSEVQVAYMGSFMDTDQRK 200 Query: 743 SMIVRQGESVILSA-QVVGNPRPTITWCKNNKPVKALPTKSDGDT-HSITILKPKKVKDE 800 + V QG + IL+ + PRP +TW + K +P+ T + ++ D Sbjct: 201 T--VSQGRAAILNLLPITSYPRPQVTWFREGH--KIIPSNRIAITLENQLVILATTTSDA 256 Query: 801 GVYTLKAENSE-GIAETSAVITV----EEPTEENAEPPLFINRFQEITVKEKGTIKLVAR 855 G Y ++A N + G +TS I + + T E P + + V L Sbjct: 257 GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316 Query: 856 VTRNPVP--SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVAS--NS 911 + PV S+TW RN IT L I+N S D+G Y C A+ S Sbjct: 317 ASARPVEDLSVTWKRNGV------RITSGLHSFGRHLTISNPTSA-DTGPYVCEAALPGS 369 Query: 912 AGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYHNKKEISG 969 A + + +E F + E +TV + CQ + +WY + IS Sbjct: 370 AFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISR 429 Query: 970 MDHR--EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPEFIRKL 1023 + + +++ G D G+ +C ++ +T T L V P F ++ Sbjct: 430 LQNPRYKVLASG---GLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRP 486 Query: 1024 QDFEVKEKDVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 D V + AIL E++ + + W+R+ I+ + L I + Sbjct: 487 VDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQ 546 Query: 1083 DEGEYSCIL--RDESCTAEVTV-VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VR 1138 D G Y+C + S A T+ V I+ ++ V KG AT T + +R Sbjct: 547 DAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLR 606 Query: 1139 --WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192 W KD + S+ ++ ++ K L I D G+YSCE+ GN A L V Sbjct: 607 YVWKKDNVALTPSSTSRIVVE-KDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVI 665 Query: 1193 E 1193 E Sbjct: 666 E 666 Score = 70.5 bits (165), Expect = 5e-10 Identities = 118/503 (23%), Positives = 195/503 (38%), Gaps = 57/503 (11%) Query: 635 TFSKKPKAQYVDEGSDILLECR-LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 +F + + V +G +L + + P P + W +G +I+P I++ +E+ + Sbjct: 192 SFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQL----- 246 Query: 694 VLKITNVKKFQEGTYTVVAVN-REGE------ASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 V+ T G Y V AVN + GE L I + T E P ++ P + V Sbjct: 247 VILATTTS--DAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSV 304 Query: 747 RQGESVILSAQVVGNPRP----TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802 G S + + + + RP ++TW +N + + S G +TI P D G Sbjct: 305 VAGSSE-TTLECIASARPVEDLSVTWKRNGVRITS-GLHSFG--RHLTISNPTSA-DTGP 359 Query: 803 YTLKAE---NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN 859 Y +A ++ A +A + + EP AEP I+ + + T+ + + Sbjct: 360 YVCEAALPGSAFEPARATAFLFIIEPPYFTAEPE------SRISAEVEETVDIGCQAMGV 413 Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P+P++ WY++ IS + L I + E DSG ++C ASN G+ Sbjct: 414 PLPTLQWYKDAISISRLQNPRYKVLASG-GLRIQKLRPE-DSGIFQCFASNEGGEIQ--T 469 Query: 920 RVTIDVEKVTFVKHLQKSYET--EEGKTVILECQTSHT--VSTKW-YHNKKEISGMDHRE 974 +DV + V Q+ +T +G T IL C+ S + W N SG Sbjct: 470 HTYLDVTNIAPV-FTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIP 528 Query: 975 IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEK 1031 D G C + E S T+ + +D V + Sbjct: 529 RFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKG 588 Query: 1032 DVAILEVEINSE---TADVVWERDGEIIKPKK-NKYDFEKRGHIRKLYIRNTSVHDEGEY 1087 A L + + VW++D + P ++ EK G L I T D G+Y Sbjct: 589 TTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDG---SLLISQTWSGDIGDY 645 Query: 1088 SCILRDE----SCTAEVTVVELP 1106 SC + E S A + V+ELP Sbjct: 646 SCEIVSEGGNDSRMARLEVIELP 668 Score = 63.3 bits (147), Expect = 7e-08 Identities = 50/216 (23%), Positives = 96/216 (44%), Gaps = 11/216 (5%) Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX---XXARIQKLSINTTYQF 1837 + +V ++W +G SPI+ Y VE+ + WK + L+ TYQF Sbjct: 683 SHAVVLSWV-RPFDGNSPILYYIVELSENSSPWKVHLSNVGPEMTGVTVSGLTPARTYQF 741 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW-TEPESNGGSP 1896 R+ A NE+G Y+++ + P + P+N V S T++S+ ++W PE+ Sbjct: 742 RVCAVNEVGRG-QYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGV 800 Query: 1897 ITNYIIEFKT--VKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTES 1954 + YI+ ++ + G+ + +T V+ + ++ + +++A N G L S Sbjct: 801 LRGYILRYRLAGLPGEYQQRNIT-SPEVNYCLVTDLIIWTQYEIQVAAYN--GAGLGVFS 857 Query: 1955 QSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 ++V VP+ P ++ V S + W P Sbjct: 858 RAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPP 893 Score = 61.7 bits (143), Expect = 2e-07 Identities = 102/467 (21%), Positives = 178/467 (38%), Gaps = 44/467 (9%) Query: 1043 ETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC-------ILRDES 1095 E V W+R+G I + + R L I N + D G Y C Sbjct: 323 EDLSVTWKRNGVRITSGLHSFG-------RHLTISNPTSADTGPYVCEAALPGSAFEPAR 375 Query: 1096 CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TKGDAL--VRWFKDG---SEIQFS 1149 TA + ++E P T +++ + T +I G L ++W+KD S +Q Sbjct: 376 ATAFLFIIE--PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNP 433 Query: 1150 NHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEF 1205 + L G L+I +D+G + C E G + L V + FT R P Sbjct: 434 RYKVLASGG----LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQR-PVD 488 Query: 1206 ILVPANTDAYLTVEIPDETLD-VTWYKKKSVIED-TEKFTLISDVKKRTLIIRKCTEDDQ 1263 V A L E+ +TW ++ ++ + + ++ L I D Sbjct: 489 TTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDA 548 Query: 1264 CEYTCVLLDAKSTTKLKVEVVEFP-PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 YTC + + + + + IV ++ + +G+ TL P+ + ++ Sbjct: 549 GNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYV 608 Query: 1323 -VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + T + K SL I + + D G Y + + G+ + +++ P Sbjct: 609 WKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELP 668 Query: 1382 SPPGKPNILEIDSSS----INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNI--TK 1435 P N+L +SS + + W P + GNS I+YY+VE E + + + N+ Sbjct: 669 HSP--QNLLVSPNSSHSHAVVLSWVRPFD-GNSPILYYIVELSENSSPWKVHLSNVGPEM 725 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSP 1482 T ++ L +Y+FR AVNEV S T + +E P Sbjct: 726 TGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPP 772 Score = 58.4 bits (135), Expect = 2e-06 Identities = 92/402 (22%), Positives = 153/402 (38%), Gaps = 30/402 (7%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDD--GGLELTKYAIEKHEPDNNRWIKVADVDRD- 1722 P+ P V ++ ++ W PP G+ Y + D + V + D Sbjct: 869 PTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN-QGYKLLAWPADAPEAVTVVTIAPDF 927 Query: 1723 --VETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 V I L + Y V+ G + S P ++ T D P +D Sbjct: 928 HGVHHGHITNLKKFTAYFTSVLCFTTPG--DGPPSTPQLVWTQEDKPGAVGHLSFTEILD 985 Query: 1781 NESVYITWF-PSEKNGGSPIIDYKVEIKQEGK---KWKXXXXXXXXXARIQKLSINTTYQ 1836 S+ ++W P EKNG I Y++ + G+ + +IQ LS TTY Sbjct: 986 T-SLKVSWQEPLEKNG--IITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYT 1042 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + A +GT L +S I+ G P P N V+S + RS TL++ P +G + Sbjct: 1043 IDVAAVTAVGTGLVTSST--ISSGVPPDLPGAPSNLVISNISPRSATLQF-RPGYDGKTS 1099 Query: 1897 ITNYIIEFKT---VKGKSWTKIVTVGGSVHEHCIE--NIKEKDEIIFRISAENTVGVSLP 1951 I+ +I+E + + W + +E N+ FR+ N VG S Sbjct: 1100 ISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPY 1159 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW---GTPEWDGGAPLLGYNIAI--R 2006 + S V A PT+ + +R + W +++G +GY I Sbjct: 1160 SPSSRVIQTLQAPPDVAPTS-VTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRS 1218 Query: 2007 DVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 D+ + +V D +F I +L E Y +++ A N +G Sbjct: 1219 DLQSSAVAQVVS-DRLEREFTIEELEEWMEYELQMQAFNAVG 1259 Score = 55.6 bits (128), Expect = 1e-05 Identities = 30/94 (31%), Positives = 45/94 (47%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 ++AP+F ++ DG T C+V G P+P ITW R+ I+ + Sbjct: 477 NIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESG 536 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L I VF +DAG +TC A N G +++ L V Sbjct: 537 GLQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570 Score = 55.2 bits (127), Expect = 2e-05 Identities = 81/344 (23%), Positives = 133/344 (38%), Gaps = 30/344 (8%) Query: 1725 TYC-IQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNES 1783 T C + L + Y + A N +G S A S P+ + P+ + Sbjct: 1660 TMCELTHLKKYRRYEVIMTAYNIIGESPA--SAPVEVFVGEAAPAMAPQNVQVTPLTASQ 1717 Query: 1784 VYITWFP---SEKNG---GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 + +TW P +NG G I ++ + + E +K K R++ L+ +T Y Sbjct: 1718 LEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPV-VRLKNLTSHTKYLV 1776 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 I A N G P + + G+T P P SE TS ++ + W EP + G Sbjct: 1777 SISAFNAAGDG-PKSDPQQ---GRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGI- 1831 Query: 1897 ITNYIIEFK---TVKGKSWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAEN-TVGVSLP 1951 + Y + ++ V+G S V V G+ + ++ + FR+ A T G L Sbjct: 1832 LQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQ 1891 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 + E P +P ++ + S +T T G P GY I R + Sbjct: 1892 ANITAGPAE------GSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEG 1945 Query: 2012 MW-MEVGKV--DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 +W M V + + ++ L + TY R+ A NE G EP Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEP 1989 Score = 53.2 bits (122), Expect = 8e-05 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 10/199 (5%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDG---KKLKTAKATYENRXXXXXXXXXX 1542 +P I+ E E +++ C GVP P + WY+D +L+ + Sbjct: 391 EPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRP 450 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 ++C A N+ GE++T + + PV T + G ++ + G P Sbjct: 451 EDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFT--QRPVDTTVTDGMTAILRCEVSGAPK 508 Query: 1602 PEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P + W + + L + ++ ++I + + YT A+NT G+ + TL Sbjct: 509 PAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATL 568 Query: 1661 KVYDKPS---KPEGPVIMR 1676 V+++ S PE V+++ Sbjct: 569 TVWNRTSIVHPPEDHVVIK 587 Score = 45.6 bits (103), Expect = 0.015 Identities = 35/137 (25%), Positives = 65/137 (47%), Gaps = 10/137 (7%) Query: 1355 AGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKPNIL-----EIDSSSINICWDEPENTG 1408 A I++L + G + +E V +K P P L E+ + S+ + W P + G Sbjct: 1447 AYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW-VPGSDG 1505 Query: 1409 NSTIIYYVVEYQEIDTTEWISVKN-ITKTQTS--IQNLKTNSSYRFRAYAVNEVDISDAS 1465 S I Y+ ++ +E+ EW + + I+ T+ + L+ +SY+ R A N++ SD S Sbjct: 1506 ASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFS 1565 Query: 1466 ETTEYYKVIKETKIQSP 1482 TE +++ + P Sbjct: 1566 SETEAVTTLQDVPGEPP 1582 Score = 43.6 bits (98), Expect = 0.061 Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 5/126 (3%) Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV-IMREISRESVTIEWK 1688 +++++L + + + ++A ++ + P P ++ S +T++W Sbjct: 1864 LKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWT 1923 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRW-IKVADVDRDVETYCIQ--KLNENCEYMFRVIAQN 1745 G T Y IE D W + V D+ R +Y + KL + Y FRV+A N Sbjct: 1924 EG-HSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVN 1982 Query: 1746 PVGFSE 1751 G+ E Sbjct: 1983 EAGYGE 1988 Score = 41.5 bits (93), Expect = 0.25 Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 8/103 (7%) Query: 1370 DVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 +++ N+T PG P ++ +S + + W E ++G++ YV+E + D W Sbjct: 1889 ELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEG-HSGDTPTTGYVIEARPSDEGLW 1947 Query: 1428 -ISVKNITKTQTS----IQNLKTNSSYRFRAYAVNEVDISDAS 1465 + VK+I ++ TS + L+ +Y FR AVNE + S Sbjct: 1948 DMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPS 1990 Score = 41.1 bits (92), Expect = 0.33 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 2/75 (2%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 TV CQ G P P + W++ I Q+ + Y L I+++ PED+G F C A Sbjct: 403 TVDIGCQAMGVPLPTLQWYKDAISISRLQNPR--YKVLASGGLRIQKLRPEDSGIFQCFA 460 Query: 586 KNAAGFASSTTELIV 600 N G + T L V Sbjct: 461 SNEGGEIQTHTYLDV 475 Score = 39.9 bits (89), Expect = 0.75 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 1/96 (1%) Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTM 2012 +S+ RLE SP + S+ V+ SW P +DG +P+L Y + + + + Sbjct: 656 DSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRP-FDGNSPILYYIVELSENSSPW 714 Query: 2013 WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + + V + L+ TY R+ A NE+G Sbjct: 715 KVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVG 750 Score = 37.9 bits (84), Expect = 3.0 Identities = 21/79 (26%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPVI 1674 Y+ + + + + L+ S K ++A+N G +S E + D P +P G V Sbjct: 1527 YSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVS 1586 Query: 1675 MREISRESVTIEWKPPLDD 1693 + SV I+W+PP D+ Sbjct: 1587 ATPHTTSSVLIQWQPPRDE 1605 >UniRef50_UPI0000DB7802 Cluster: PREDICTED: similar to Neogenin precursor; n=1; Apis mellifera|Rep: PREDICTED: similar to Neogenin precursor - Apis mellifera Length = 1492 Score = 97.1 bits (231), Expect = 5e-18 Identities = 88/326 (26%), Positives = 146/326 (44%), Gaps = 26/326 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F K+P+ V G L C L+A I K E + ++++S M + S Sbjct: 124 PGFEKEPQDTMVYPGQIAYLSCTLLATSSSLIIQWLKDEH-----PLIISMDSRMTILPS 178 Query: 694 -VLKITNVKKFQEGTYTVVAVNR-----EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 L+I NVK G+Y A + +A L ++ I P + +PL+ +I+ Sbjct: 179 GALEIDNVKTEDVGSYRCNASSYGQYRLSNKAQLGLLSDIDQESTPPVFIAKPLQQVII- 237 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTL 805 +G ++ L G P+P+I W K+ + KS + + L V+ D G Y Sbjct: 238 EGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQC 297 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +AEN I + +A + V+ P P FI + ++ E ++ + P P IT Sbjct: 298 RAENEVEILDATADLIVQVP-------PRFIKKPEDKIASENQDLEFECEIYGKPQPKIT 350 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W +N E I+ S Q +G N+ + N ID+G ++C+ +NSAG AR+TI+ Sbjct: 351 WLKNGERITLS-AYWQIVNGYNLRI---NGLLPIDAGIFQCIGTNSAGTVQAAARLTINQ 406 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQ 951 K + H + +T K ++L Q Sbjct: 407 PKKA-ISHKSTTPKTVPKKKLLLHRQ 431 Score = 89.0 bits (211), Expect = 1e-15 Identities = 156/727 (21%), Positives = 270/727 (37%), Gaps = 59/727 (8%) Query: 1342 SASLTIKKVENTDAGIYKLRLENN-----CGHADVEMNVTILDKPSPP---GKPNILEID 1393 S +L I V+ D G Y+ + A + + I + +PP KP + ++ Sbjct: 178 SGALEIDNVKTEDVGSYRCNASSYGQYRLSNKAQLGLLSDIDQESTPPVFIAKP-LQQVI 236 Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQNLKTNSSYRFR 1452 I + N I ++ + ID T + S I + I N++ + ++ Sbjct: 237 IEGSTITLECAANGYPKPSILWLKDGVAIDLTSFKSRYSRIAASSLVISNVEEIDNGSYQ 296 Query: 1453 AYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPK 1512 A NEV+I DA T + ++ ++KP I +E N+D+E C G PQPK Sbjct: 297 CRAENEVEILDA--TADLI-----VQVPPRFIKKPEDKIASE-NQDLEFECEIYGKPQPK 348 Query: 1513 VTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 +TW ++G+++ T A ++ N ++CI N G V+ + + I Q Sbjct: 349 ITWLKNGERI-TLSAYWQIVNGYNLRINGLLPIDAGIFQCIGTNSAGTVQAAARLTINQ- 406 Query: 1571 PVITISNEDIKQKHKVGDEWLVTAVIEGIP---PPEVIWYKNGNKLENDKEYNITTKEKT 1627 P IS++ K + L+ + P ++ + N + + Sbjct: 407 PKKAISHKSTTPKTVPKKKLLLHRQLYNKTWQHPSTLLGHTMSAFTPNPPLSISPSDDPA 466 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 + SH + +T S+E ++ PS P + + ++ VT+ W Sbjct: 467 DLPGSVRFPNSHYDPKSPFIDDTDSLESIEGSV-----PSAPRN-LSLVIVTARFVTLRW 520 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPV 1747 + P + G L Y K E +V + + +E I+ L + Y FRV+A N Sbjct: 521 QEPENTNGEILNYYIYYKQEGAQRE--RVINTQQKLEA-VIRGLQPSMTYHFRVVALNER 577 Query: 1748 GFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIK 1807 G + E + T +VP + S+ ++W E G + EI Sbjct: 578 GSGISSEILQVTTLTEANVPGPPLNLEGYAT-SSVSIALSW--EEPQGDNE------EIT 628 Query: 1808 QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 +E + L T Y ++ A NE G + S D + + P Sbjct: 629 RE---------TTSTMHDLIDLVPYTEYSIKVQAVNENGPGV--FSRDIVVRTYSAQPTQ 677 Query: 1868 QPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P N V + S+ ++W P IT Y I ++ S + G+ + Sbjct: 678 PPHNVTVEPVSPTSIMIRWEPPLEGQNGIITGYKIRYRRHDRASPPVNIATEGNQRSRVL 737 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIR-MVGSNIVMT 1985 +++ RI A N G TE Q E + P P +R V S+ + Sbjct: 738 TGLEKHVVYQVRICALNVNGTGPWTEWIQIETYETESDENRVPNTPSNLRTKVMSDYIQV 797 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARN 2045 W P+ D + GY + +EV +D F I L Y+I + A N Sbjct: 798 FWNPPK-DQSIKVKGYKLGWGKGVPD--VEVRLLDGKERSFTIDQLEPITEYVISLRATN 854 Query: 2046 EIGLSEP 2052 + G +P Sbjct: 855 DAGDGQP 861 Score = 78.2 bits (184), Expect = 2e-12 Identities = 52/198 (26%), Positives = 92/198 (46%), Gaps = 13/198 (6%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E PP F KP Q + EGS I LEC P+P I WL G I +++ Sbjct: 221 ESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAI----DLTSFKSRYSR 276 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREG--EASLPIVLKIKTGEKEPPQVIEPLKSMIVR 747 + S L I+NV++ G+Y A N +A+ +++++ PP+ I+ + I Sbjct: 277 IAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQV------PPRFIKKPEDKIAS 330 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 + + + ++ G P+P ITW KN + + + +++ I + D G++ Sbjct: 331 ENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQIVNGYNLRINGLLPI-DAGIFQCIG 389 Query: 808 ENSEGIAETSAVITVEEP 825 NS G + +A +T+ +P Sbjct: 390 TNSAGTVQAAARLTINQP 407 Score = 65.3 bits (152), Expect = 2e-08 Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Query: 504 EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDD 563 +++S P+F+ K + +GST+ EC GYP+P I W + I + F+ Y Sbjct: 219 DQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLT-SFKSRYSRI 277 Query: 564 NVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 ++LVI V D G++ C A+N +T +LIV+ P Sbjct: 278 AASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVP 317 Score = 58.8 bits (136), Expect = 2e-06 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F++K K + ++FEC++ G P+P+ITW + I S Y+ N L Sbjct: 318 PRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERITLS----AYWQIVNGYNLR 373 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + P DAG F C+ N+AG + L + P Sbjct: 374 INGLLPIDAGIFQCIGTNSAGTVQAAARLTINQP 407 Score = 58.8 bits (136), Expect = 2e-06 Identities = 95/440 (21%), Positives = 172/440 (39%), Gaps = 27/440 (6%) Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYD-KPSKPEGPVIMREISRESVTIEWKPPLDDGGLE 1697 +S K N G S ++ ++ Y +P++P V + +S S+ I W+PPL+ Sbjct: 647 YSIKVQAVNENGPGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRWEPPLEGQNGI 706 Query: 1698 LTKYAIEKHEPDN-NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEAL 1753 +T Y I D + + +A + + + + L ++ Y R+ A N G ++E + Sbjct: 707 ITGYKIRYRRHDRASPPVNIA-TEGNQRSRVLTGLEKHVVYQVRICALNVNGTGPWTEWI 765 Query: 1754 ESEPIVIKTALD-VPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK 1812 + E ++ + VP+ D V+ W P K+ + YK+ + Sbjct: 766 QIETYETESDENRVPNTPSNLRTKVMSDYIQVF--WNPP-KDQSIKVKGYKLGWGKGVPD 822 Query: 1813 WKXXXXXXXXXA-RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT---IGKTLTPPSQ 1868 + + I +L T Y + A N+ G P ++ + T + + P Sbjct: 823 VEVRLLDGKERSFTIDQLEPITEYVISLRATNDAGDGQPAYANVRTTERSVSEFSAPLLP 882 Query: 1869 PRNFVVSESTSRSVTLKWTE---PESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P S + +V L WT+ P++ + Y++ + T S + + Sbjct: 883 PVGLKASVLSDTTVVLYWTDTTLPKTQFVTDNRYYVVRY-TSHHHSSNPRYKYHNATDLN 941 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSN--IV 1983 C+ N K ++ + + G S V + PS L I+ + V Sbjct: 942 CMIN-DLKPNTLYEFTVKLVKGKRESLWSMVVSNQTQEAAPSSAPRNLTIQSIEDRPTSV 1000 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIR-DVTK--TMWMEVGKVDVNTLKFNIRDLSENHTYMIR 2040 + W P+ G P+ GY I D TK W+ G + T +F ++ L + TY + Sbjct: 1001 LLRWQPPKQPNG-PITGYIIFYSIDNTKWDRDWLIEGVIGDKT-EFIVKGLQPSMTYYFK 1058 Query: 2041 IYARNEIGLSEPLESDEPFK 2060 I ARN G P + PFK Sbjct: 1059 IQARNSKGYG-PFSTTYPFK 1077 Score = 50.0 bits (114), Expect = 7e-04 Identities = 20/49 (40%), Positives = 28/49 (57%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 AD++ +PP F KKP+ + E D+ EC + P+P I WL GE I Sbjct: 310 ADLIVQVPPRFIKKPEDKIASENQDLEFECEIYGKPQPKITWLKNGERI 358 Score = 48.4 bits (110), Expect = 0.002 Identities = 75/377 (19%), Positives = 140/377 (37%), Gaps = 27/377 (7%) Query: 1024 QDFEVKEKDVAILEVEINSETA--DVVWERD-GEIIKPKKNKYDFE-KRGHIRKLYIRNT 1079 QD V++ + A L+ E NS ++ W D G+ I + Y + G + + T Sbjct: 32 QDVVVEQGNPARLDCEANSSFGKPNIQWRTDDGQPINFIGDSYRSQLSNGSLYINSVYGT 91 Query: 1080 SVHDEGEYSCILRDESCTA---EVTVVELP--PEIITRLQNQKVNKGNKATFEIEL--TK 1132 S+ G Y C+ + A + +++ P Q+ V G A L T Sbjct: 92 SLELTGSYQCLASVDDIGAIVSRIATIKIASLPGFEKEPQDTMVYPGQIAYLSCTLLATS 151 Query: 1133 GDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE--------VGNSK 1184 +++W KD + S ++TI L+I + +D G Y C + N Sbjct: 152 SSLIIQWLKDEHPLIISMDSRMTIL-PSGALEIDNVKTEDVGSYRCNASSYGQYRLSNKA 210 Query: 1185 CTAILT-VEEPSIN--FTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEK 1241 +L+ +++ S F + + +++ +T + W K I+ T Sbjct: 211 QLGLLSDIDQESTPPVFIAKPLQQVIIEGSTITLECAANGYPKPSILWLKDGVAIDLTSF 270 Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIK 1300 + S + +L+I E D Y C + + +V+ PP+ + + Sbjct: 271 KSRYSRIAASSLVISNVEEIDNGSYQCRAENEVEILDATADLIVQVPPRFIKKPEDKIAS 330 Query: 1301 RGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKL 1360 D+ + PQP W+ N + I + + +L I + DAGI++ Sbjct: 331 ENQDLEFECEIYGKPQPKITWLKNGERITLSAYWQ---IVNGYNLRINGLLPIDAGIFQC 387 Query: 1361 RLENNCGHADVEMNVTI 1377 N+ G +TI Sbjct: 388 IGTNSAGTVQAAARLTI 404 Score = 39.5 bits (88), Expect = 0.99 Identities = 55/262 (20%), Positives = 98/262 (37%), Gaps = 17/262 (6%) Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 EY +V A N G + S IV++T P+ + S+ I W P + Sbjct: 646 EYSIKVQAVNENG--PGVFSRDIVVRTYSAQPTQPPHNVTVEPVSPTSIMIRWEPPLEGQ 703 Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYT 1852 I YK+ ++ + R + L + YQ RI A N GT P+T Sbjct: 704 NGIITGYKIRYRRHDRASPPVNIATEGNQRSRVLTGLEKHVVYQVRICALNVNGTG-PWT 762 Query: 1853 SDDKITIGKTLTP----PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVK 1908 +I +T + P+ P N + ++ S + + W P+ + Y + + K Sbjct: 763 EWIQIETYETESDENRVPNTPSN-LRTKVMSDYIQVFWNPPKDQ-SIKVKGYKLGWG--K 818 Query: 1909 GKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 G ++ + G I+ ++ E + + A N G P + E+ + S Sbjct: 819 GVPDVEVRLLDGKERSFTIDQLEPITEYVISLRATNDAGDGQPAYANVRTTERSVSEFSA 878 Query: 1969 PTAP---LEIRMVGSNIVMTSW 1987 P P L+ ++ V+ W Sbjct: 879 PLLPPVGLKASVLSDTTVVLYW 900 >UniRef50_Q96MS0 Cluster: Roundabout homolog 3 precursor; n=23; Euteleostomi|Rep: Roundabout homolog 3 precursor - Homo sapiens (Human) Length = 1386 Score = 97.1 bits (231), Expect = 5e-18 Identities = 81/319 (25%), Positives = 134/319 (42%), Gaps = 23/319 (7%) Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664 SD G + V A+++ P+F ++P Q V + + C + P P Sbjct: 229 SDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPR 288 Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 + W + E+ I SD ++ I +V EGTYT VA N G A Sbjct: 289 LRWRKEDGELPTGR---YEIRSDHSLW-----IGHVSAEDEGTYTCVAENSVGRAEASGS 340 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDG 784 L + PPQ++ + + GESV + GNP P I W K V P++S Sbjct: 341 LSVHV----PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQ 396 Query: 785 DTHSITILKPKKVK-------DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFIN 837 T ++ ++ D G Y +A + G A++ ++ + + PP+ + Sbjct: 397 PTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGL-PPVILQ 455 Query: 838 RFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS 897 T+ ++ L RVT NP PS+ W ++ + + + + N L I NV Sbjct: 456 GPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTM--ANGTLYIANV-Q 512 Query: 898 EIDSGDYKCVASNSAGKSS 916 E+D G Y CVA +S G+++ Sbjct: 513 EMDMGFYSCVAKSSTGEAT 531 Score = 75.8 bits (178), Expect = 1e-11 Identities = 116/487 (23%), Positives = 201/487 (41%), Gaps = 65/487 (13%) Query: 833 PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL-- 890 P + + ++ V L R P P+I WY+N ++ T+ ++ + L Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVA---TVREDPRAHRLLLPS 120 Query: 891 -------VITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEE 942 ++ + D G Y CVA N G + S A + + V + F + + Sbjct: 121 GALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDF-RQSPGNVVVAV 179 Query: 943 GKTVILEC--QTSHTV-STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 G+ +LEC H S W + + + R I+ G+ D G+ C Sbjct: 180 GEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKS---DAGMYVC 236 Query: 1000 IVK----DQETSTMLVVKETIPEFIRK-LQDFEVKEKDVAILEVEINSETADVVWER-DG 1053 + ++E++ V+ P F+R+ + + + V L + W + DG Sbjct: 237 VASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDG 296 Query: 1054 EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEII 1110 E+ +Y+ + H L+I + S DEG Y+C+ + AE + V +PP+++ Sbjct: 297 EL---PTGRYEI-RSDH--SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLV 350 Query: 1111 TRLQNQKVNKGNKATFEIELTKGD--ALVRWFKDGSEIQFSNHIQLTIDGK-----KQKL 1163 T+ Q+Q G F+ E TKG+ + W K+GS++ L G+ + +L Sbjct: 351 TQPQDQMAAPGESVAFQCE-TKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQL 409 Query: 1164 KIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILV-PANTDAYL-- 1216 I DAG Y C+ G+ A+L ++ S++ LP IL PAN L Sbjct: 410 NITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLD---GLPPVILQGPANQTLVLGS 466 Query: 1217 TVEIP-----DETLDVTWYKKKSVIE-DTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 +V +P + V W K ++ D +F +++ TL I E D Y+CV Sbjct: 467 SVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMAN---GTLYIANVQEMDMGFYSCV- 522 Query: 1271 LDAKSTT 1277 AKS+T Sbjct: 523 --AKSST 527 Score = 75.4 bits (177), Expect = 2e-11 Identities = 83/348 (23%), Positives = 148/348 (42%), Gaps = 48/348 (13%) Query: 527 VQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAK 586 V F C+V+G P P++ W ++ + P+ +++ D +L I V ED GT+TCVA+ Sbjct: 275 VTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDH----SLWIGHVSAEDEGTYTCVAE 329 Query: 587 NAAGFASSTTELIVEAP---LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 N+ G A ++ L V P ++ +M +G PP P Sbjct: 330 NSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCET-----KGNPP-----PAIF 379 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 + EGS +L LF + + P SV+ L IT V++ Sbjct: 380 WQKEGSQVL---------------LFPSQSLQPTGRFSVSPRGQ-------LNITAVQRG 417 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGN 761 G Y AV+ G +L+IK + PP +++ + + G SV L +V GN Sbjct: 418 DAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P+P++ W K+ + ++ + + + + D G Y+ A++S G A S + Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 + E + +PP + + + +V +T+N + ++TW N Sbjct: 538 MREDWGVSPDPPT-----EPSSPPGAPSQPVVTEITKNSI-TLTWKPN 579 Score = 70.9 bits (166), Expect = 4e-10 Identities = 114/532 (21%), Positives = 199/532 (37%), Gaps = 56/532 (10%) Query: 1262 DQCEYTCVL---LDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL-LVDYQAFPQP 1317 D+ YTCV L A ++ +EV + G L V + P+P Sbjct: 137 DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEP 196 Query: 1318 NDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVT 1376 + W K + K + I + L + +DAG+Y N G + V Sbjct: 197 SVSW---RKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVM 253 Query: 1377 ILDKPSPPGKP--NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNIT 1434 +L++PS +P ++ D+ +C + + + + E E+ T + +++ Sbjct: 254 VLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPR---LRWRKEDGELPTGRY-EIRS-- 307 Query: 1435 KTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTE 1494 I ++ + A N V ++AS + + + V +P + Sbjct: 308 DHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH-------VPPQLVTQPQDQMAA- 359 Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKL---------KTAKATYENRXXXXXXXXXXXXX 1545 P E + C G P P + W ++G ++ T + + R Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDA 419 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVI----TISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 Y C A + G + ++ I+ + I Q +G + + G P Sbjct: 420 GYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQ 479 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P V W K+G L+ D T T + I ++ Y+ A ++ G ++ LK Sbjct: 480 PSVRWKKDGQWLQGDDLQFKTMANGT--LYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537 Query: 1662 VY-------DKPSKPEGPV------IMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP 1708 + D P++P P ++ EI++ S+T+ WKP G +T Y IE P Sbjct: 538 MREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPN-PQTGAAVTSYVIEAFSP 596 Query: 1709 -DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758 N W VAD +ET+ + L N Y+F V A G SE + SEP+ Sbjct: 597 AAGNTWRTVAD-GVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPV 647 Score = 62.1 bits (144), Expect = 2e-07 Identities = 75/329 (22%), Positives = 127/329 (38%), Gaps = 24/329 (7%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV---PDENISVAIES 686 E P ++P V G L CR P P+I W G + D + Sbjct: 60 EDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLP 119 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVIEPLKSMI 745 ++ + + EG YT VA N G AS L++ + Q P +++ Sbjct: 120 SGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQ--SP-GNVV 176 Query: 746 VRQGESVILS-AQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 V GE +L G+P P+++W K+ +K + + + K D G+Y Sbjct: 177 VAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLK-SDAGMYV 235 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N G E++A + E P F+ R V + + V +P P + Sbjct: 236 CVASNMAGERESAAAEVMV------LERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRL 289 Query: 865 TWYRNNEIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 W + + E T ++ + L I +V +E D G Y CVA NS G++ +++ Sbjct: 290 RWRKED-----GELPTGRYEIRSDHSLWIGHVSAE-DEGTYTCVAENSVGRAEASGSLSV 343 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQT 952 V + + G++V +C+T Sbjct: 344 HVPPQLVTQ--PQDQMAAPGESVAFQCET 370 Score = 60.1 bits (139), Expect = 7e-07 Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 34/223 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ--TAIIKPSQDFQM--YYDDDNV 565 P V + + + G +V F+C+ +G P P I W ++ ++ PSQ Q + Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 L I V DAG + C A + AG ++ +A L G+ Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAG------SILAKALLEIKGAS--------------- 445 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 L+G+PP + P Q + GS + L CR+ P+P + W G+ + D+ + + Sbjct: 446 ---LDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDD---LQFK 499 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 + M L I NV++ G Y+ VA + GEA+ LK++ Sbjct: 500 T---MANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMR 539 Score = 56.4 bits (130), Expect = 8e-06 Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 9/113 (7%) Query: 1864 TPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSV 1922 +PP P VV+E T S+TL W +P G+ +T+Y+IE F G +W + V G + Sbjct: 554 SPPGAPSQPVVTEITKNSITLTW-KPNPQTGAAVTSYVIEAFSPAAGNTW-RTVADGVQL 611 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLE 1974 H + ++ +F + A G+S P+ S+ VR T S P+ P+E Sbjct: 612 ETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVR-----TQDSSPSRPVE 659 >UniRef50_Q4S2G4 Cluster: Chromosome undetermined SCAF14761, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14761, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 912 Score = 96.7 bits (230), Expect = 6e-18 Identities = 88/299 (29%), Positives = 126/299 (42%), Gaps = 26/299 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP P +EG I L C+ +P+PD+ W G + ++ + +H Sbjct: 600 VPPEIHAGPYHYIANEGVSITLFCKSSGVPKPDVVW---GGSL----SLGTMLPVSVHQM 652 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + I + G Y + N G AS I L + T + P LK++I G+S Sbjct: 653 AT-FHIPHPTTDDAGIYVCTSTNPVGYASREIQLSVNTKPRIQPAATL-LKALI---GQS 707 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 V L V G P P +TW N PV +T + I K K + D+G Y A NS Sbjct: 708 VTLPCVVQGEPSPEVTWFHNGLPVGIK------NTTPLRIQKAK-LNDQGTYKCVATNSA 760 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G ETS + AEP + E K I A +P P I WYRN Sbjct: 761 G-QETSEIKLDILDAPSFAEPG---DALLEKVANTKVIIPCPAE--GSPRPKIRWYRNGL 814 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I P ++ + F E+ L I++ S SGD+ CVA+N AG R+ I+ + F Sbjct: 815 EIHPEQSSPELFVSEDGALTISSA-SASHSGDFMCVATNEAGSVERKTRLKIEGDPPVF 872 Score = 93.9 bits (223), Expect = 4e-17 Identities = 105/411 (25%), Positives = 158/411 (38%), Gaps = 37/411 (9%) Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSEMTVXXXXXX 619 DD TL IR V DAG +TCVA + AG A+ T L V E+ +E T+ Sbjct: 438 DDYHGTLHIRGVQKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDCTQ 497 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAW-LFKGEEIVPDE 678 + P FS+ P G ++ L C P+P ++W G +I+ Sbjct: 498 RRFSPLTE-----DPLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGS 552 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 + D H L I V EG Y A N G L + TG PP++ Sbjct: 553 RSRMVQLEDGH-----LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSV-TG-LVPPEIH 605 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVK 798 I +G S+ L + G P+P + W + LP S + I P Sbjct: 606 AGPYHYIANEGVSITLFCKSSGVPKPDVVWGGSLSLGTMLPV-SVHQMATFHIPHP-TTD 663 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 D G+Y + N G A ++V T+ +P + + + + T+ V V Sbjct: 664 DAGIYVCTSTNPVGYASREIQLSVN--TKPRIQPAATL---LKALIGQSVTLPCV--VQG 716 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P +TW+ N + T + D G YKCVA+NSAG+ + Sbjct: 717 EPSPEVTWFHNGLPVGIKNTTPLRIQKAKLN----------DQGTYKCVATNSAGQETSE 766 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKWYHNKKEI 967 ++ I ++ +F + E VI+ C + S +WY N EI Sbjct: 767 IKLDI-LDAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEI 816 Score = 70.1 bits (164), Expect = 6e-10 Identities = 82/369 (22%), Positives = 146/369 (39%), Gaps = 38/369 (10%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEF-PPKIVDYEREYRIKRGSDVTLLV 1309 L+I+ D+ Y C + T K ++ V PP+I Y G +TL Sbjct: 564 LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFC 623 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 P+P+ W + + P + A+ I DAGIY N G+A Sbjct: 624 KSSGVPKPDVVWGGSLSLGTML----PVSVHQMATFHIPHPTTDDAGIYVCTSTNPVGYA 679 Query: 1370 DVEMNVTILDKPS-PPGKPNILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 E+ +++ KP P + + S+ + C + E + T + + Sbjct: 680 SREIQLSVNTKPRIQPAATLLKALIGQSVTLPCVVQGEPSPEVTWFHNGLP--------- 730 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 + +KN T + IQ K N ++ A N S ET+E IK + +P+ +P Sbjct: 731 VGIKNTTPLR--IQKAKLNDQGTYKCVATN----SAGQETSE----IKLDILDAPSFAEP 780 Query: 1488 LKNITTE-PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE----NRXXXXXXXXXX 1542 + + N + + C G P+PK+ WYR+G ++ +++ E Sbjct: 781 GDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGALTISSASA 840 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPP 1601 + C+A N+ G VE + I+ PV I E ++ + + + +G P Sbjct: 841 SHSGDFMCVATNEAGSVERKTRLKIEGDPPVFGIQEEKVRMNGSL----TLACMTKGFPE 896 Query: 1602 PEVIWYKNG 1610 P++ W+K+G Sbjct: 897 PKIQWFKDG 905 Score = 65.3 bits (152), Expect = 2e-08 Identities = 56/229 (24%), Positives = 95/229 (41%), Gaps = 30/229 (13%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L C + P P++ W G + V I++ + L+I K +GT Sbjct: 705 GQSVTLPCVVQGEPSPEVTWFHNG--------LPVGIKNT-----TPLRIQKAKLNDQGT 751 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES-VILSAQVVGNPRPTI 766 Y VA N G+ + I L I + P EP +++ + + VI+ G+PRP I Sbjct: 752 YKCVATNSAGQETSEIKLDIL----DAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKI 807 Query: 767 TWCKNN---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 W +N P ++ P + ++TI G + A N G E + +E Sbjct: 808 RWYRNGLEIHPEQSSPELFVSEDGALTI-SSASASHSGDFMCVATNEAGSVERKTRLKIE 866 Query: 824 EPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 +PP+F QE V+ G++ L P P I W+++ ++ Sbjct: 867 ------GDPPVF--GIQEEKVRMNGSLTLACMTKGFPEPKIQWFKDGQV 907 Score = 65.3 bits (152), Expect = 2e-08 Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 6/170 (3%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + + L C+ G P P+VTW+ +G + +N YKC+A N Sbjct: 706 QSVTLPCVVQGEPSPEVTWFHNGLPVGI-----KNTTPLRIQKAKLNDQGTYKCVATNSA 760 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEND 1616 G+ + + I P + + +K + ++ EG P P++ WY+NG ++ + Sbjct: 761 GQETSEIKLDILDAPSFAEPGDALLEK-VANTKVIIPCPAEGSPRPKIRWYRNGLEIHPE 819 Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + + + I SHS + A+N AG+ + LK+ P Sbjct: 820 QSSPELFVSEDGALTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDP 869 Score = 59.3 bits (137), Expect = 1e-06 Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 14/193 (7%) Query: 1496 NEDIELT--CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 NE + +T C GVP+P V W + Y C + Sbjct: 614 NEGVSITLFCKSSGVPKPDVVWGGSLSLGTMLPVSVHQMATFHIPHPTTDDAGIYVCTST 673 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N G + + KP I + +K +G + V++G P PEV W+ NG + Sbjct: 674 NPVGYASREIQLSVNTKPRIQPAATLLKAL--IGQSVTLPCVVQGEPSPEVTWFHNGLPV 731 Query: 1614 ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPE-GP 1672 + T+ +RI++ K + Y A+N+AG + E+ L + D PS E G Sbjct: 732 GI---------KNTTPLRIQKAKLNDQGTYKCVATNSAGQETSEIKLDILDAPSFAEPGD 782 Query: 1673 VIMREISRESVTI 1685 ++ +++ V I Sbjct: 783 ALLEKVANTKVII 795 Score = 50.0 bits (114), Expect = 7e-04 Identities = 56/271 (20%), Positives = 100/271 (36%), Gaps = 15/271 (5%) Query: 1420 QEIDTTEWISVKNITK-TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 Q++D ++ V + T T +LK F+ + SD T + + E Sbjct: 450 QKVDAGQYTCVASSPAGTATGTVSLKVGGESAFQCFNTEPTLPSDC--TQRRFSPLTEDP 507 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKT---AKATYENRXX 1534 + S T + I E++ L C G PQP V+W+R DG+++ T ++ Sbjct: 508 LFSETPADLMAKI----GENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGH 563 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y C A N G ++T + + I G + Sbjct: 564 LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSVTGLVPPEIHAGPYHYIANEGVSITLFC 623 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 G+P P+V+W G L ++ + + I + Y ++N G + Sbjct: 624 KSSGVPKPDVVW---GGSLSLGTMLPVSV-HQMATFHIPHPTTDDAGIYVCTSTNPVGYA 679 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTI 1685 S E+ L V KP +++ + +SVT+ Sbjct: 680 SREIQLSVNTKPRIQPAATLLKALIGQSVTL 710 Score = 48.8 bits (111), Expect = 0.002 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDF-QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 C EG PRP+I W+R I P Q +++ +D L I +G F CVA N A Sbjct: 797 CPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSED--GALTISSASASHSGDFMCVATNEA 854 Query: 590 GFASSTTELIVE 601 G T L +E Sbjct: 855 GSVERKTRLKIE 866 Score = 47.6 bits (108), Expect = 0.004 Identities = 62/252 (24%), Positives = 96/252 (38%), Gaps = 52/252 (20%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +V C V+G P P++TWF + N L I++ D GT+ C Sbjct: 705 GQSVTLPCVVQGEPSPEVTWFHNGLPV----------GIKNTTPLRIQKAKLNDQGTYKC 754 Query: 584 VAKNAAGFASSTTEL-IVEAP-LSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 VA N+AG +S +L I++AP ++ G + ++ P S +PK Sbjct: 755 VATNSAGQETSEIKLDILDAPSFAEPGDAL--------LEKVANTKVIIPCPAEGSPRPK 806 Query: 642 AQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVK 701 ++ G +I PE LF E+ L I++ Sbjct: 807 IRWYRNGLEI--------HPEQSSPELFVSED-------------------GALTISSAS 839 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 G + VA N G LKI E +PP + ++ VR S+ L+ G Sbjct: 840 ASHSGDFMCVATNEAGSVERKTRLKI---EGDPP--VFGIQEEKVRMNGSLTLACMTKGF 894 Query: 762 PRPTITWCKNNK 773 P P I W K+ + Sbjct: 895 PEPKIQWFKDGQ 906 Score = 41.1 bits (92), Expect = 0.33 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 5/93 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVAT 567 P+F E G V C G P+P ++W R I+ S+ + +D + Sbjct: 507 PLFSETPADLMAKIGENVTLRCSARGSPQPTVSWHRHDGRQILTGSRSRMVQLEDGH--- 563 Query: 568 LVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 L+I+ V+ D G + C AKN G + L V Sbjct: 564 LLIQGVWLSDEGLYVCEAKNPFGTIKTGARLSV 596 Score = 39.1 bits (87), Expect = 1.3 Identities = 77/352 (21%), Positives = 141/352 (40%), Gaps = 37/352 (10%) Query: 1047 VVWER-DG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT----AEV 1100 V W R DG +I+ +++ + GH L I+ + DEG Y C ++ T A + Sbjct: 538 VSWHRHDGRQILTGSRSRMVQLEDGH---LLIQGVWLSDEGLYVCEAKNPFGTIKTGARL 594 Query: 1101 TVVEL-PPEIITRLQNQKVNKGNKATFEIE---LTKGDALVRWFKDGSEIQFSNHIQLTI 1156 +V L PPEI + N+G T + + K D + W G + + +++ Sbjct: 595 SVTGLVPPEIHAGPYHYIANEGVSITLFCKSSGVPKPDVV--W---GGSLSLGTMLPVSV 649 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL-PEFILVPANTDAY 1215 + I DDAG Y C N A ++ S+N R+ P L+ A Sbjct: 650 H-QMATFHIPHPTTDDAGIYVCTSTNPVGYASREIQL-SVNTKPRIQPAATLLKALIGQS 707 Query: 1216 LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRT-LIIRKCTEDDQCEYTCVLL 1271 +T+ + + +VTW+ + +K T L I+K +DQ Y CV Sbjct: 708 VTLPCVVQGEPSPEVTWFHNGLPV----------GIKNTTPLRIQKAKLNDQGTYKCVAT 757 Query: 1272 DA--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIK 1329 ++ + T+++K+++++ P + + V + + P+P W N I Sbjct: 758 NSAGQETSEIKLDILDAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIH 817 Query: 1330 KCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + + S+ +LTI + +G + N G + + + I P Sbjct: 818 PEQSSPELFVSEDGALTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDP 869 Score = 37.5 bits (83), Expect = 4.0 Identities = 38/196 (19%), Positives = 75/196 (38%), Gaps = 15/196 (7%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI 1196 V WF +G + N L I QK K L+D G Y C NS ++ + Sbjct: 722 VTWFHNGLPVGIKNTTPLRI----QKAK-----LNDQGTYKCVATNSAGQETSEIKLDIL 772 Query: 1197 NF-TLRLPEFILVPANTDAYLTVEIPDETLD---VTWYKKKSVIEDTEKFTLISDVKKRT 1252 + + P L+ + + + P E + WY+ I + + + Sbjct: 773 DAPSFAEPGDALLEKVANTKVIIPCPAEGSPRPKIRWYRNGLEIHPEQSSPELFVSEDGA 832 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 L I + ++ CV + + + K + +E P + + E +++ +TL Sbjct: 833 LTISSASASHSGDFMCVATNEAGSVERKTRLKIEGDPPVFGIQEE-KVRMNGSLTLACMT 891 Query: 1312 QAFPQPNDEWIVNSKI 1327 + FP+P +W + ++ Sbjct: 892 KGFPEPKIQWFKDGQV 907 >UniRef50_Q1CVL1 Cluster: FG-GAP repeat/fibronectin type III domain protein; n=1; Myxococcus xanthus DK 1622|Rep: FG-GAP repeat/fibronectin type III domain protein - Myxococcus xanthus (strain DK 1622) Length = 1267 Score = 96.7 bits (230), Expect = 6e-18 Identities = 95/404 (23%), Positives = 156/404 (38%), Gaps = 37/404 (9%) Query: 1665 KPSKPEGPVIMREISRES----VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720 KP +P P R++S + VT+ W P +GG +T Y + ++ ++V Sbjct: 64 KPPEPTAPSAPRQVSAMTDPGTVTLSWFEPAQNGGSAITGYDVGVEPLEDGIQVQVEGT- 122 Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 T + L Y F + A+N VG S + + + DVP+ Sbjct: 123 ----TARVTGLRAGGTYRFTITARNAVGVSPVARVDSVNLP---DVPTAPVALGVERG-- 173 Query: 1781 NESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIY 1840 + V +TW +GG ++ Y V G + L+ F ++ Sbjct: 174 DRQVRVTWNAPASDGGRSVLHYVVTAHPSGAS--VATDSPVRTTTVSGLTNGVASTFTVH 231 Query: 1841 ARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNY 1900 A N +G P +++ + P P + S R V++ W PE GG P++ Y Sbjct: 232 AVNAVGAG-PASAESTAVV--PAAQPGTPVSVAASPGV-REVSVSWQPPEDTGGLPVSGY 287 Query: 1901 IIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLE 1960 ++ T T V G E N+++ E F +SA N VG + + S R Sbjct: 288 VV---TASPGGTTH--QVEGLASEATFTNLQDDTEYTFTVSARNDVGQGPDSSTASAR-- 340 Query: 1961 KHATVPSPPTAPLEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV 2019 HA PP AP ++ G + +W P DG + L GY + + + +EV Sbjct: 341 THA----PPGAPASVQAEPGVRSLTVAWAPPVSDGRSRLTGYTVMAQ--PSGVRIEVSAD 394 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 + + D+ I + ARN +G S + EP K P Sbjct: 395 QHGAV---LEDVPSTKAQTISVVARNAVGDSPAATAGEPVKSQP 435 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/131 (23%), Positives = 53/131 (40%), Gaps = 5/131 (3%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSS--S 1396 DS + T+ + N A + + N G T + + PG P + Sbjct: 209 DSPVRTTTVSGLTNGVASTFTVHAVNAVGAGPASAESTAVVPAAQPGTPVSVAASPGVRE 268 Query: 1397 INICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 +++ W PE+TG + YVV TT V+ + ++ + NL+ ++ Y F A Sbjct: 269 VSVSWQPPEDTGGLPVSGYVVTASPGGTTH--QVEGLA-SEATFTNLQDDTEYTFTVSAR 325 Query: 1457 NEVDISDASET 1467 N+V S T Sbjct: 326 NDVGQGPDSST 336 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 1380 KPSPPGKPNILEI--DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 +P+ P P + D ++ + W EP G S I Y V + ++ + I V+ + T Sbjct: 67 EPTAPSAPRQVSAMTDPGTVTLSWFEPAQNGGSAITGYDVGVEPLE--DGIQVQ-VEGTT 123 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDIS 1462 + L+ +YRF A N V +S Sbjct: 124 ARVTGLRAGGTYRFTITARNAVGVS 148 >UniRef50_Q4T1M4 Cluster: Chromosome undetermined SCAF10538, whole genome shotgun sequence; n=9; Euteleostomi|Rep: Chromosome undetermined SCAF10538, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2293 Score = 96.3 bits (229), Expect = 8e-18 Identities = 112/489 (22%), Positives = 185/489 (37%), Gaps = 41/489 (8%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L C+ P P WL + PD + L I + + GTY Sbjct: 287 LPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTG--------LLIESAQPGDSGTYVCEV 338 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N G A + L +K K V+ P K + G V LS V G+ ++W +N Sbjct: 339 WNSYGNAEVVGRLYVKQPLKA---VVSPRK-VKGSVGSKVSLSCSVSGSDEYELSWYRNG 394 Query: 773 KPV-KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + + + G I++ D G Y A + A+ + +E+ T Sbjct: 395 EIIYPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGT----- 449 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE-IISPSETITQNFDGENIEL 890 P ++ F E V + LV V P P +W +++ +I S +++ + Sbjct: 450 -PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHV 508 Query: 891 V----ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 V +T+ + D G Y+C NSAG H AR I+V V+ + K+ G+ Sbjct: 509 VSQLNVTHTQVQ-DGGQYRCTCGNSAGVVHHQAR--INVRGRASVRAM-KNLTAIAGRDA 564 Query: 947 ILECQTSHT--VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ 1004 + C+ S KWY N + +HR+ E D G C V Q Sbjct: 565 FVHCRVIGYPYYSIKWYKNSALLP-FNHRQRAFENNGTLKLSNVQQV-DAGEYTCKVMVQ 622 Query: 1005 ET---STMLVVKETIPEFIR--KLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPK 1059 S + V+ +P +I+ + Q F + ++ V D+ W++DG I P Sbjct: 623 PNKMDSQSVHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI-PA 681 Query: 1060 KNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE---VTVVELPPEIITRLQNQ 1116 + L I N + G Y+CI R+E+ E +V +PP+ + + ++Q Sbjct: 682 GLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPEDQ 741 Query: 1117 KVNKGNKAT 1125 G T Sbjct: 742 DGIYGKTVT 750 Score = 89.4 bits (212), Expect = 9e-16 Identities = 131/595 (22%), Positives = 227/595 (38%), Gaps = 62/595 (10%) Query: 772 NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 NK + L T S G + + +L + + T E SA + V +PT NAE Sbjct: 211 NKRQRYLIT-SAGALYILDVLPEDGLNNYRCTTRHRYTGETRQSNSARLIVSDPT--NAE 267 Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 P + ++ F+ V ++L + + P P W ++N + P Q G IE Sbjct: 268 PAI-LDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTGLLIESA 326 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ 951 DSG Y C NS G + R+ + V + + G V L C Sbjct: 327 QPG-----DSGTYVCEVWNSYGNAEVVGRLYVKQPLKAVVS--PRKVKGSVGSKVSLSCS 379 Query: 952 TSHT--VSTKWYHNKKEI--------SGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 S + WY N + I +G++ +I EG D G +C Sbjct: 380 VSGSDEYELSWYRNGEIIYPGNSVRFTGLNRENLIMEG---------MSKSDGGAYQCFA 430 Query: 1002 KDQETS----TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGE-I 1055 + + S +++++ P+ + + V + L + + W D + + Sbjct: 431 RKGKMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPV 490 Query: 1056 IKPKKNKY-DFEK-RGH-IRKLYIRNTSVHDEGEYSCILRDESCTA--EVTVVELPPEII 1110 IK + +E GH + +L + +T V D G+Y C + + + + + Sbjct: 491 IKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRASV 550 Query: 1111 TRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 ++N G A + ++W+K+ + + F NH Q + LK+ + Sbjct: 551 RAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPF-NHRQRAFE-NNGTLKLSNVQ 608 Query: 1170 LDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL---TVEIP----- 1221 DAGEY+C+V ++ S++ +R+P +I P + V IP Sbjct: 609 QVDAGEYTCKV----MVQPNKMDSQSVHVRVRVPPYI-QPFEFQRFTIGQRVFIPCVVMS 663 Query: 1222 -DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 D LD+TW K I T+ + +L I T D YTC+ + + + + Sbjct: 664 GDRPLDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQ 723 Query: 1281 VE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHT 1334 +V PP+ V + G VTL + +P P W +SK +C HT Sbjct: 724 SRLIVRVPPQFVVQPEDQDGIYGKTVTLNCSAEGYPPPTIVW-EHSK--GRCHHT 775 Score = 74.1 bits (174), Expect = 4e-11 Identities = 105/496 (21%), Positives = 182/496 (36%), Gaps = 38/496 (7%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP 794 P +++ + V V L + G P P W K+N P++ P T + +++ Sbjct: 268 PAILDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLE--PDSRFRQTVTGLLIES 325 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVA 854 + D G Y + NS G AE + V++P + P +++ + L Sbjct: 326 AQPGDSGTYVCEVWNSYGNAEVVGRLYVKQPLKAVVSP-------RKVKGSVGSKVSLSC 378 Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGK 914 V+ + ++WYRN EII P ++ F G N E +I S+ D G Y+C A GK Sbjct: 379 SVSGSDEYELSWYRNGEIIYPGNSV--RFTGLNRENLIMEGMSKSDGGAYQCFARK--GK 434 Query: 915 SSHGARVTIDVEKVTFVKHLQKSYE--TEEGKTVILECQTSHTVSTK--WYHNKKEISGM 970 S V + +E T K L E + V L C T + W + + Sbjct: 435 MSAQDFVQVILEDGT-PKILSSFSEKVVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKD 493 Query: 971 DHREI----IQEGR-XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI--PEFIRKL 1023 H + EG D G +C + + + +R + Sbjct: 494 SHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRASVRAM 553 Query: 1024 QDF-EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 ++ + +D + I + W ++ ++ + FE G ++ + N Sbjct: 554 KNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLK---LSNVQQV 610 Query: 1083 DEGEYSC---ILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--V 1137 D GEY+C + ++ + V V P I + Q+ G + + GD + Sbjct: 611 DAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDI 670 Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 W KDG I + + L+I + D G Y+C N VE S Sbjct: 671 TWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAA----AVEHQSRL 726 Query: 1198 FTLRLPEFILVPANTD 1213 P+F++ P + D Sbjct: 727 IVRVPPQFVVQPEDQD 742 Score = 74.1 bits (174), Expect = 4e-11 Identities = 94/445 (21%), Positives = 165/445 (37%), Gaps = 50/445 (11%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V C V G +++W+R II P + + N L++ + D G + C Sbjct: 371 GSKVSLSCSVSGSDEYELSWYRNGEIIYPGNSVR--FTGLNRENLIMEGMSKSDGGAYQC 428 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A+ A ++I+E D I +FS+K Sbjct: 429 FARKGKMSAQDFVQVILE-------------------------DGTPKILSSFSEK---- 459 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKK 702 V+ + L C + P P +W + ++ D + + ES S L +T+ + Sbjct: 460 VVNPNEPVFLVCNVKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHTQV 519 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 G Y N G + ++ G + +K++ G + +V+G P Sbjct: 520 QDGGQYRCTCGNSAGVVHHQARINVR-GRAS----VRAMKNLTAIAGRDAFVHCRVIGYP 574 Query: 763 RPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV-IT 821 +I W KN+ + + + + L + D G YT K ++ +V + Sbjct: 575 YYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNKMDSQSVHVR 634 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V P P + FQ T+ ++ I V P+ ITW ++ I +T Sbjct: 635 VRVP------PYIQPFEFQRFTIGQRVFIPCVVMSGDRPL-DITWQKDGRPIPAGLGVTV 687 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 + L I N+ + +G+Y C+A N A H +R+ + V V+ + + Sbjct: 688 DNIDFTSSLRINNLTPD-HNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQ--PEDQDGI 744 Query: 942 EGKTVILECQTS--HTVSTKWYHNK 964 GKTV L C + W H+K Sbjct: 745 YGKTVTLNCSAEGYPPPTIVWEHSK 769 Score = 68.5 bits (160), Expect = 2e-09 Identities = 91/486 (18%), Positives = 176/486 (36%), Gaps = 37/486 (7%) Query: 1138 RWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVEE 1193 RW KD S ++ + + T+ G L I D+G Y CEV GN++ L V++ Sbjct: 300 RWLKDNSPLEPDSRFRQTVTG----LLIESAQPGDSGTYVCEVWNSYGNAEVVGRLYVKQ 355 Query: 1194 PSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 P + P + + L+ + + +++WY+ +I + + + Sbjct: 356 PL--KAVVSPRKVKGSVGSKVSLSCSVSGSDEYELSWYRNGEIIYPGNS-VRFTGLNREN 412 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVV--EFPPKIVDYEREYRIKRGSDVTLLVD 1310 LI+ ++ D Y C K + + V+V+ + PKI+ E + V L+ + Sbjct: 413 LIMEGMSKSDGGAYQCFARKGKMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCN 472 Query: 1311 YQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKS----ASLTIKKVENTDAGIYKLRLENN 1365 + P P W + + +IK H +S + L + + D G Y+ N+ Sbjct: 473 VKGTPPPRCSWSLDDDPVIKDSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNS 532 Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT 1425 G + + + + S N+ I + + +I Y Y I Sbjct: 533 AGVVHHQARINVRGRASVRAMKNLTAIAGRDAFV---------HCRVIGY--PYYSIKWY 581 Query: 1426 EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE 1485 + ++ Q + +N T + E + + +++ P Sbjct: 582 KNSALLPFNHRQRAFENNGTLKLSNVQQVDAGEYTCKVMVQPNKMDSQSVHVRVRVPPYI 641 Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQP-KVTWYRDGKKLKTA-KATYEN---RXXXXXXXX 1540 +P + + + + C+ +P +TW +DG+ + T +N Sbjct: 642 QPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNL 701 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y CIA N+ VE + ++ P + ED Q G + EG P Sbjct: 702 TPDHNGNYTCIARNEAAAVEHQSRLIVRVPPQFVVQPED--QDGIYGKTVTLNCSAEGYP 759 Query: 1601 PPEVIW 1606 PP ++W Sbjct: 760 PPTIVW 765 Score = 62.1 bits (144), Expect = 2e-07 Identities = 102/479 (21%), Positives = 179/479 (37%), Gaps = 49/479 (10%) Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 VI++ N E + N+T + + + + L++ + + + A +AG + V Sbjct: 1219 VIYWANLPDGELGEIRNVTAVQPS--LELDGLEKYTNYRIQVLAFTSAGDGVRSEQIYVR 1276 Query: 1664 DKPSKPEGPVIMREISRES--VTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 K P P ++ + S V + W PPL G+ + KY I + + + + Sbjct: 1277 TKEDVPGPPAGVKAAASSSSAVFVSWLPPLKLNGI-IRKYIIFCSDL-HPMVMSEFEASP 1334 Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 D Y I L N +Y V+A G SE I ++ P+ N Sbjct: 1335 DAHFYRIPNLAGNRQYTIWVVAVTAAGHGN--NSEKITVEPLAKAPARILTF-------N 1385 Query: 1782 ESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYA 1841 +V W + D +K R + + N ++ R Sbjct: 1386 GTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGR-RTVHANGSFFIRTVK 1444 Query: 1842 RNEIGTSLPYTSD----DKITIG-KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + G + D+IT+ + PP QPR V+++T+ S+TL W P NGGS Sbjct: 1445 AEDSGNYSCVAGNTWGGDEITLNLQVQVPPDQPR-LTVTKTTTTSITLSWI-PGDNGGSS 1502 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG-------VS 1949 I YI+++ + W + S + +EN+K F ++A+N VG + Sbjct: 1503 IRGYILQYSEDNSEQWGSF-PISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEIIE 1561 Query: 1950 LPTESQSVRL-----------EKHATV----PSPPTAPLEIRMVGS-NIVMTSWGTPEW- 1992 T + R + H+ + PS P E + S N W Sbjct: 1562 AKTHGKGNRCGHQEAGGVATRQTHSHLWRLSPSEPQFAKEHELFTSINSTRARLNLAGWN 1621 Query: 1993 DGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 +GG P+ + + R V + W + + T + + DL E Y +++ N G +E Sbjct: 1622 NGGCPITSFVLEYRAVDSSTWTSAQRTSL-TKSYVLYDLQEATWYELQMKVTNSAGSAE 1679 Score = 58.8 bits (136), Expect = 2e-06 Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 11/165 (6%) Query: 1598 GIPPPEVIWYK---NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 G PPP V W K NG + T S I+ +K S Y+ A NT G Sbjct: 1404 GDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFF-IRTVKAEDSGNYSCVAGNTWGGD 1462 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + + L+V P +P + + + + S+T+ W P D+GG + Y ++ E ++ +W Sbjct: 1463 EITLNLQVQVPPDQPR--LTVTKTTTTSITLSWIPG-DNGGSSIRGYILQYSEDNSEQWG 1519 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG---FSEALESE 1756 + +Y ++ L Y F + AQN VG SE +E++ Sbjct: 1520 SF-PISPSERSYRLENLKCGTWYKFTLTAQNVVGPGRISEIIEAK 1563 Score = 56.0 bits (129), Expect = 1e-05 Identities = 50/203 (24%), Positives = 92/203 (45%), Gaps = 14/203 (6%) Query: 1275 STTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 ++ K+ VE + + P +I+ + D+ L P P +WI S Sbjct: 1365 NSEKITVEPLAKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSA---NGTP 1421 Query: 1334 TKPSIDSK-----SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 T +D + + S I+ V+ D+G Y N G ++ +N+ + P P + Sbjct: 1422 TNVLVDGRRTVHANGSFFIRTVKAEDSGNYSCVAGNTWGGDEITLNLQVQVPPDQP-RLT 1480 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTS--IQNLKTN 1446 + + ++SI + W P + G S+I Y+++Y E ++ +W S I+ ++ S ++NLK Sbjct: 1481 VTKTTTTSITLSWI-PGDNGGSSIRGYILQYSEDNSEQWGSFP-ISPSERSYRLENLKCG 1538 Query: 1447 SSYRFRAYAVNEVDISDASETTE 1469 + Y+F A N V SE E Sbjct: 1539 TWYKFTLTAQNVVGPGRISEIIE 1561 Score = 50.0 bits (114), Expect = 7e-04 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 5/102 (4%) Query: 503 SEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD 562 S+ + P ++ + V+ C+ GYP P+ W + + ++P F+ Sbjct: 261 SDPTNAEPAILDGFERREVMISHRVELPCKASGYPAPKYRWLKDNSPLEPDSRFR----- 315 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPL 604 V L+I P D+GT+ C N+ G A L V+ PL Sbjct: 316 QTVTGLLIESAQPGDSGTYVCEVWNSYGNAEVVGRLYVKQPL 357 Score = 50.0 bits (114), Expect = 7e-04 Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 7/137 (5%) Query: 1854 DDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWT 1913 +D+ I T+ P P + E R++ L+WT +G SPIT Y IE K K SW Sbjct: 946 EDRGIIQLTVQEPPDPPEVEIREVKDRTIALRWTMG-FDGNSPITGYDIECKN-KSASWL 1003 Query: 1914 KI-VT--VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 VT V +++ I ++ R+ A+N +G S P+ ++ ++ A P P Sbjct: 1004 SAQVTKDVSPQLNQATIIDLHPSSTYNIRMVAKNVIGNSNPSNELTITTDEAA--PDGPP 1061 Query: 1971 APLEIRMVGSNIVMTSW 1987 + + + SW Sbjct: 1062 LDVTLEPTSPQSIKVSW 1078 Score = 48.8 bits (111), Expect = 0.002 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 1964 TVPSPPTAP-LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWM--EVGK-V 2019 TV PP P +EIR V + W T +DG +P+ GY+I ++ + + W+ +V K V Sbjct: 954 TVQEPPDPPEVEIREVKDRTIALRW-TMGFDGNSPITGYDIECKNKSAS-WLSAQVTKDV 1011 Query: 2020 DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + I DL + TY IR+ A+N IG S P Sbjct: 1012 SPQLNQATIIDLHPSSTYNIRMVAKNVIGNSNP 1044 Score = 48.4 bits (110), Expect = 0.002 Identities = 44/204 (21%), Positives = 75/204 (36%), Gaps = 7/204 (3%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXX 1543 + +KN+T D + C G P + WY++ L + +EN Sbjct: 551 RAMKNLTAIAGRDAFVHCRVIGYPYYSIKWYKNSALLPFNHRQRAFENNGTLKLSNVQQV 610 Query: 1544 XXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVI-EGIPP 1601 Y C ++++ V V ++ P I Q+ +G + V+ G P Sbjct: 611 DAGEYTCKVMVQPNKMDSQSVHVRVRVPPYIQPFEF---QRFTIGQRVFIPCVVMSGDRP 667 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 ++ W K+G + + + TS +RI L H+ YT A N A + L Sbjct: 668 LDITWQKDGRPIPAGLGVTVDNIDFTSSLRINNLTPDHNGNYTCIARNEAAAVEHQSRLI 727 Query: 1662 VYDKPSKPEGPVIMREISRESVTI 1685 V P P I ++VT+ Sbjct: 728 VRVPPQFVVQPEDQDGIYGKTVTL 751 Score = 46.8 bits (106), Expect = 0.007 Identities = 31/145 (21%), Positives = 55/145 (37%), Gaps = 3/145 (2%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 +EL C G P PK W +D L+ + Y C +N +G Sbjct: 285 VELPCKASGYPAPKYRWLKDNSPLEPDSRFRQTVTGLLIESAQPGDSGTYVCEVWNSYGN 344 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 E + ++Q +S K K VG + ++ + G E+ WY+NG + Sbjct: 345 AEVVGRLYVKQPLKAVVSPR--KVKGSVGSKVSLSCSVSGSDEYELSWYRNGEIIYPGNS 402 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKY 1643 T + ++I ++ + +S Y Sbjct: 403 VRFTGLNRENLI-MEGMSKSDGGAY 426 Score = 44.8 bits (101), Expect = 0.026 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 8/146 (5%) Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 D H Y +I N+ ++ T VVAV G + + ++ K P +++ ++ Sbjct: 1335 DAHFY----RIPNLAGNRQYTIWVVAVTAAGHGNNSEKITVEPLAKAPARILTFNGTVTT 1390 Query: 747 RQGESVILSAQVVGNPRPTITWCK---NNKPVKAL-PTKSDGDTHSITILKPKKVKDEGV 802 + ++L + VG+P PT+ W K N P L + + ++ K +D G Sbjct: 1391 PWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLVDGRRTVHANGSFFIRTVKAEDSGN 1450 Query: 803 YTLKAENSEGIAETSAVITVEEPTEE 828 Y+ A N+ G E + + V+ P ++ Sbjct: 1451 YSCVAGNTWGGDEITLNLQVQVPPDQ 1476 Score = 42.3 bits (95), Expect = 0.14 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 1794 NGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIGTS 1848 +G SPI Y +E K + W ++ + +I ++TY R+ A+N IG S Sbjct: 983 DGNSPITGYDIECKNKSASWLSAQVTKDVSPQLNQATIIDLHPSSTYNIRMVAKNVIGNS 1042 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTS-RSVTLKW-TEPESNG 1893 P +++TI P P V E TS +S+ + W P G Sbjct: 1043 NP---SNELTITTDEAAPDGPPLDVTLEPTSPQSIKVSWKVRPRPQG 1086 Score = 41.9 bits (94), Expect = 0.19 Identities = 54/237 (22%), Positives = 98/237 (41%), Gaps = 15/237 (6%) Query: 695 LKITNVKKFQEGTYTVVAVNREGEA--SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L++ ++K+ V+A G+ S I ++ K PP ++ S S Sbjct: 1243 LELDGLEKYTNYRIQVLAFTSAGDGVRSEQIYVRTKEDVPGPPAGVKAAASSSSAVFVSW 1302 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 + ++ G R I +C + P+ ++ D H I + ++ + A + G Sbjct: 1303 LPPLKLNGIIRKYIIFCSDLHPMVMSEFEASPDAHFYRIPNLAGNRQYTIWVV-AVTAAG 1361 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 S ITVE P A+ P I F +T I L + +P P++ W + + Sbjct: 1362 HGNNSEKITVE-PL---AKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSA 1417 Query: 872 IISPSETIT--QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +P+ + + N I V +E DSG+Y CVA N+ G G +T++++ Sbjct: 1418 NGTPTNVLVDGRRTVHANGSFFIRTVKAE-DSGNYSCVAGNTWG----GDEITLNLQ 1469 Score = 41.5 bits (93), Expect = 0.25 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 17/185 (9%) Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDE 1403 SL I D+G + N+ G + +T+ + P PP + I E+ +I + W Sbjct: 922 SLQIMPTVREDSGFFSCHAINSFGEDRGIIQLTVQEPPDPP-EVEIREVKDRTIALRWTM 980 Query: 1404 PENTGNSTIIYYVVEYQEIDTTEWISVKNITK------TQTSIQNLKTNSSYRFRAYAVN 1457 + GNS I Y +E + + W+S + +TK Q +I +L +S+Y R A N Sbjct: 981 GFD-GNSPITGYDIECKN-KSASWLSAQ-VTKDVSPQLNQATIIDLHPSSTYNIRMVAKN 1037 Query: 1458 EVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR 1517 + S+ S ++ T +P + P ++T EP + + P+P+ T + Sbjct: 1038 VIGNSNPSN-----ELTITTDEAAP--DGPPLDVTLEPTSPQSIKVSWKVRPRPQGTCLK 1090 Query: 1518 DGKKL 1522 + L Sbjct: 1091 GRRAL 1095 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 2/85 (2%) Query: 650 DILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYT 709 DI+L C+ V P P + W+ KG N+ V +H S I VK G Y+ Sbjct: 1395 DIVLPCKAVGDPPPTVKWI-KGSANGTPTNVLVDGRRTVHANGSFF-IRTVKAEDSGNYS 1452 Query: 710 VVAVNREGEASLPIVLKIKTGEKEP 734 VA N G + + L+++ +P Sbjct: 1453 CVAGNTWGGDEITLNLQVQVPPDQP 1477 Score = 37.1 bits (82), Expect = 5.3 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 2/107 (1%) Query: 499 EKPTSEEQSMAPIFVEKLRPK-HTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 EK T E + AP + TP + C+ G P P + W + +A P+ Sbjct: 1367 EKITVEPLAKAPARILTFNGTVTTPWMKDIVLPCKAVGDPPPTVKWIKGSANGTPTNVLV 1426 Query: 558 MYYDDDNV-ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + + IR V ED+G ++CVA N G T L V+ P Sbjct: 1427 DGRRTVHANGSFFIRTVKAEDSGNYSCVAGNTWGGDEITLNLQVQVP 1473 Score = 36.7 bits (81), Expect = 7.0 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRP-QITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P +++ + G V C V RP ITW + I P+ + D ++L Sbjct: 638 PPYIQPFEFQRFTIGQRVFIPCVVMSGDRPLDITWQKDGRPI-PAGLGVTVDNIDFTSSL 696 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + P+ G +TC+A+N A + LIV P Sbjct: 697 RINNLTPDHNGNYTCIARNEAAAVEHQSRLIVRVP 731 Score = 36.3 bits (80), Expect = 9.2 Identities = 34/177 (19%), Positives = 69/177 (38%), Gaps = 9/177 (5%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIAFND 1555 + L+C G + +++WYR+G+ + + + T NR Y+C A Sbjct: 374 VSLSCSVSGSDEYELSWYRNGEIIYPGNSVRFTGLNRENLIMEGMSKSDGGAYQCFARKG 433 Query: 1556 HGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 + V ++ +S+ K + +LV V +G PPP W + + + Sbjct: 434 KMSAQDFVQVILEDGTPKILSSFSEKVVNPNEPVFLVCNV-KGTPPPRCSWSLDDDPVIK 492 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHS-----SKYTIEASNTAGTSSVEVTLKVYDKPS 1667 D +++ E + +L +H+ +Y N+AG + + V + S Sbjct: 493 DSHHHLGHYESHEGHVVSQLNVTHTQVQDGGQYRCTCGNSAGVVHHQARINVRGRAS 549 >UniRef50_Q9N3X8 Cluster: Protein sidekick homolog precursor; n=2; Caenorhabditis|Rep: Protein sidekick homolog precursor - Caenorhabditis elegans Length = 2325 Score = 96.3 bits (229), Expect = 8e-18 Identities = 186/914 (20%), Positives = 358/914 (39%), Gaps = 83/914 (9%) Query: 1193 EPSINFTLRLPEFILVPANTDAYLT--VEIPDETLDVTWYKKKSVIE-DTEKFTLISDVK 1249 EPS ++ P+ + V + TD + ++ W I+ D K+ L +D Sbjct: 455 EPSQKL-IKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTND-- 511 Query: 1250 KRTLIIRKCTEDDQCEYTCVLL--DAKSTTKLKVE---VVEFPPKIVDYEREYRIKRGSD 1304 L I + D+ EYTC + + K+T ++V ++E+ P +++ I + Sbjct: 512 --GLAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDSLIEYGPA----DQKSLIGTNVE 565 Query: 1305 VTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLE 1363 + V + + + EW +N ++ ++ I ++ SL I++V + G Y+ R+ Sbjct: 566 FSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEYRCRVT 625 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNIL---EIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 + + + I++KP+ P + E + + + W+E + GN II + +E + Sbjct: 626 VDGREENASAMLQIIEKPAMPERVRAELHNETMPAKVRVRWNEGFD-GNEPIIKHAIEMR 684 Query: 1421 EIDTT----EWIS-VKNITKTQ------TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 + T +W + + NI K + T I++L+ +S+ FR A N+ S + Sbjct: 685 TMGPTGLWSDWTTAIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSY 744 Query: 1470 YYKVIKETKIQSP-----TVEKPLKNITT--EPNEDIELTCIFGGVPQPKV------TWY 1516 + ++ +P + P + +P E+++ + G V + ++ TW Sbjct: 745 SVTMPQQPPSAAPRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWN 804 Query: 1517 RDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIA-FNDHGEVETSCVVGIQQKPVITI 1575 K A+ T + + + F++ EV TS + +P Sbjct: 805 EKNLTTKDARNTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTS-----EGRPTQAP 859 Query: 1576 SNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYK------NGNKLENDKEYNITTKEKTSV 1629 N +K + TA + P + YK K E K+ + + Sbjct: 860 KNVRVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLT 919 Query: 1630 IRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEG--PVIMREISRESVTIEW 1687 + EL++ T T G +KV + PE + + E+ I W Sbjct: 920 TVVNELEKFGHYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITW 979 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 PL G+ +TKY I +H ++ +K +VD + I L + Y V+A Sbjct: 980 NSPLKQNGI-VTKYTI-RHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTR 1037 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 G +E ++P I +V + + P +G + I + VE Sbjct: 1038 KG-DGPVEETKFESGVPPELPGRPSMLSIGD-ISATTVQLHFTPGF-DGHTAIRQWVVEG 1094 Query: 1807 KQ-EGKKWKXXXXXXXXXAR---IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 K + + AR + L T YQ R+ A N G P S+ + Sbjct: 1095 KMADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAP--SEPSRSFETL 1152 Query: 1863 LTPPSQPRNFVVSESTSR-SVTLKWTEPESN--GGSPITNYIIEFKTVKGKSWTKIVTVG 1919 T P P + +E S S+++ WT + G P Y+I ++ + ++W ++ T Sbjct: 1153 QTNPDTPSQRLFAEPVSATSISVSWTPLLATHWNGQP-KGYLIVYREIDDENWKEVRTPA 1211 Query: 1920 GSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVG 1979 EH + +++ + +EN G SLPT+ SV+ + +VPS + + G Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTD--SVKARTYESVPSGSPRNIVVTAEG 1269 Query: 1980 SNIVMTSWG-TPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV-DV---NTLKFNIRDLSEN 2034 S + W E ++GY + + +++ + KV D+ +TL + DL Sbjct: 1270 SKAAIIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPF 1329 Query: 2035 HTYMIRIYARNEIG 2048 +Y + + A +G Sbjct: 1330 TSYHVYMSAYTIVG 1343 Score = 79.8 bits (188), Expect = 8e-13 Identities = 103/455 (22%), Positives = 174/455 (38%), Gaps = 30/455 (6%) Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG----TSSVEVTLKVYDKPSKPEGPV 1673 E N+TTK+ + + + EL + + A N G + S+EVT +P++ V Sbjct: 805 EKNLTTKDARNTL-VDELITWREYEIQVAAYNKRGLGVFSESIEVTTSE-GRPTQAPKNV 862 Query: 1674 IMREISRESVTIEWKPPLDDG--GLELT-KYAIEKHEPDNNRWIK--VADVDRDVETYCI 1728 ++ ++ +V IE+ P G+ L K K EP+ K + D DR T + Sbjct: 863 RVKVLNSTAVAIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVV 922 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 +L + Y + G + S + + T D P + N +V ITW Sbjct: 923 NELEKFGHYNLTTLCFTTPG--DGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAV-ITW 979 Query: 1789 FPSEKNGGSPIIDYKVE---IKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845 K G + Y + K K I L +T Y + A Sbjct: 980 NSPLKQNGI-VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRK 1038 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 G P + K G P +P + + ++ +V L +T P +G + I +++E K Sbjct: 1039 GDG-P-VEETKFESGVPPELPGRPSMLSIGDISATTVQLHFT-PGFDGHTAIRQWVVEGK 1095 Query: 1906 TVKGKSWTKIVTVGG-SVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHAT 1964 + + V + ++ + R+ AEN G P+E S E T Sbjct: 1096 MADSSVFAHVFNVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAPSEP-SRSFETLQT 1154 Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTP----EWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 P P+ L V + + SW TP W+G GY I R++ W EV Sbjct: 1155 NPDTPSQRLFAEPVSATSISVSW-TPLLATHWNGQPK--GYLIVYREIDDENWKEVRTPA 1211 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLES 2055 + + + + DL +Y + +++ N G S P +S Sbjct: 1212 LRSSEHTVTDLRPFTSYEVNVFSENGFGRSLPTDS 1246 Score = 72.1 bits (169), Expect = 2e-10 Identities = 86/394 (21%), Positives = 149/394 (37%), Gaps = 24/394 (6%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTK-YAIEKHEPDNNRWIKVADVDRDVE 1724 P P + +S S+++ W P L K Y I E D+ W +V Sbjct: 1156 PDTPSQRLFAEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSS 1215 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + + L Y V ++N GF +L ++ + +T VPS +++ Sbjct: 1216 EHTVTDLRPFTSYEVNVFSEN--GFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAA 1273 Query: 1785 YITWFP-SEKNGGSPIIDYKVEIKQEGKKWKXXXX-------XXXXXARIQKLSINTTYQ 1836 I W P +E + +I YK+ + E + A++ L T+Y Sbjct: 1274 IIKWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYH 1333 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 + A +G P S I+ P+ P +F S + + V +KW P S G Sbjct: 1334 VYMSAYTIVGNG-PENS-TPISFETMEDVPAPPESFQCSYISEQEVRMKWLPPGSPNGK- 1390 Query: 1897 ITNYIIEF-KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS----LP 1951 ITNYII + K+ + +S + G++ ++ + F I A N+ G S Sbjct: 1391 ITNYIISYWKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAE 1450 Query: 1952 TESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE---WDGGAPLLGYNIAIRDV 2008 + SVRL P+P L I+ P D +P+ ++ + Sbjct: 1451 VMTSSVRLPVR-NAPAPVRDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKT 1509 Query: 2009 TKTMWMEV-GKVDVNTLKFNIRDLSENHTYMIRI 2041 + W+ + K + + + I+ LS N + RI Sbjct: 1510 NEDEWITLEKKFEYSKRRSVIKHLSPNSMFRFRI 1543 Score = 65.7 bits (153), Expect = 1e-08 Identities = 123/608 (20%), Positives = 219/608 (36%), Gaps = 42/608 (6%) Query: 1486 KPLKNITTEPNED-IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-NRXXXXXXXXXXX 1543 K K++T D I + C G P P + W +G +++T Y+ Sbjct: 462 KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTNDGLAIHDIRKS 521 Query: 1544 XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 Y C + V+ + V + +I D K E+ E + Sbjct: 522 DEGEYTCEISGSN--VKATANVQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKAS 579 Query: 1604 VIWYKNGNKL--ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 V WY N L + I+ K S+I I+++ ++ +Y + + L+ Sbjct: 580 VEWYLNDVLLPVNGNSGLRISRNRKGSLI-IRQVGPDNTGEYRCRVTVDGREENASAMLQ 638 Query: 1662 VYDKPSKPE--GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDN--NRWIK 1715 + +KP+ PE + E V + W DG + K+AIE P + W Sbjct: 639 IIEKPAMPERVRAELHNETMPAKVRVRWNEGF-DGNEPIIKHAIEMRTMGPTGLWSDWTT 697 Query: 1716 VAD-VDRDVETYC----IQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIKTALDVPSX 1769 D + ++ C I+ L + FRV+A N G + +L S + + PS Sbjct: 698 AIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQ--QPPSA 755 Query: 1770 XXXXXXXXXIDNESVYITW-FPSEKNGGSPIIDYKVEIKQEGKK---W--KXXXXXXXXX 1823 SV + W P E+ ++ Y V + G W K Sbjct: 756 APRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWNEKNLTTKDARN 815 Query: 1824 ARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVT 1883 + +L Y+ ++ A N+ G + ++ ++T + P P+N V S +V Sbjct: 816 TLVDELITWREYEIQVAAYNKRGLGV-FSESIEVTTSEG-RPTQAPKNVRVKVLNSTAVA 873 Query: 1884 LKWTEPESNGGSPIT-NYIIEF---KTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 +++T PE + Y ++F + KG+ + +++ + N EK F Sbjct: 874 IEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVVNELEK----FG 929 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTA--PLEIRMVGSNIVMTSWGTPEWDGGAP 1997 T+ + P + + K T P + L I V N + +W +P G Sbjct: 930 HYNLTTLCFTTPGDGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITWNSPLKQNGI- 988 Query: 1998 LLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 + Y I + +VD +T F I L + Y + + A G P+E + Sbjct: 989 VTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKG-DGPVEETK 1047 Query: 2058 PFKVIPGE 2065 +P E Sbjct: 1048 FESGVPPE 1055 Score = 54.8 bits (126), Expect = 2e-05 Identities = 132/654 (20%), Positives = 249/654 (38%), Gaps = 53/654 (8%) Query: 1321 WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 W +S +K TK +D + + TI ++ + + G VE Sbjct: 997 WAASSPDVK----TKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKGDGPVEETKFESGV 1052 Query: 1381 PSP-PGKPNILEI-DSSSINICWD-EPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQ 1437 P PG+P++L I D S+ + P G++ I +VVE + D++ + V N++ + Sbjct: 1053 PPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWVVEGKMADSSVFAHVFNVSAPK 1112 Query: 1438 T---SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVE---KPLKNI 1491 ++ L+ + Y+ R A N SE + ++ + +T +P+ +P+ Sbjct: 1113 ARSITVTGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETL-QTNPDTPSQRLFAEPVSAT 1171 Query: 1492 TTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 + + L + G P+ + YR+ + Y+ Sbjct: 1172 SISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSSEHTVTDLRPFTSYEVN 1231 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE------VI 1605 F+++G + ++ + ++ + + V E A+I+ P E VI Sbjct: 1232 VFSENGFGRSLPTDSVKARTYESVPSGS-PRNIVVTAEGSKAAIIKWNPVAELSTNGDVI 1290 Query: 1606 WYKNGNKLENDKEYNITTK------EKTSVIRIKELK-----RSHSSKYTIEASNTAGTS 1654 YK E + TK + T + ++ +L+ + S YTI + ++ Sbjct: 1291 GYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVYMSAYTIVGNGPENST 1350 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 + + D P+ PE IS + V ++W PP G ++T Y I + R + Sbjct: 1351 PISFET-MEDVPAPPES-FQCSYISEQEVRMKWLPPGSPNG-KITNYIISYWKSHEPRSM 1407 Query: 1715 KV-ADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXX 1773 + A + ++ + LN N +Y F + A+N G SE +E + L V + Sbjct: 1408 AIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEEAVAEVMTSSVRLPVRNAPAPV 1467 Query: 1774 XXXXXIDNES-VYITWFPS-----EKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR- 1825 + + I W S ++ SP+ +V ++ + +W R Sbjct: 1468 RDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWITLEKKFEYSKRR 1527 Query: 1826 --IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTL--TPPSQPRNFVVSESTSRS 1881 I+ LS N+ ++FRI IG L + + +TL P +QP + + S Sbjct: 1528 SVIKHLSPNSMFRFRI---RFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNS 1584 Query: 1882 VTLKWTEP-ESNGGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEK 1933 V L+W P +S S Y I ++ ++W HE E I K Sbjct: 1585 VQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAIRDEHEDKEEKILAK 1638 Score = 48.8 bits (111), Expect = 0.002 Identities = 45/156 (28%), Positives = 67/156 (42%), Gaps = 11/156 (7%) Query: 1139 WFKDGSEIQFSN-HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSIN 1197 W +G EIQ N LT DG L I+D D GEY+CE+ S A V+ + Sbjct: 492 WLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATANVQVNGDS 547 Query: 1198 FTLRLPEFILVPANTDAYLTVEIPDETL---DVTWYKKKSVIEDTEKFTL-ISDVKKRTL 1253 P T+ + E+ E + V WY ++ L IS +K +L Sbjct: 548 LIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSL 607 Query: 1254 IIRKCTEDDQCEYTC-VLLDAK-STTKLKVEVVEFP 1287 IIR+ D+ EY C V +D + ++++E P Sbjct: 608 IIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEKP 643 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 8/73 (10%) Query: 638 KKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLK 696 K PK V G+D I++EC P P+I WL G EI D N+ + +D L Sbjct: 462 KTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTD-NVKYDLTND------GLA 514 Query: 697 ITNVKKFQEGTYT 709 I +++K EG YT Sbjct: 515 IHDIRKSDEGEYT 527 Score = 43.2 bits (97), Expect = 0.081 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 1042 SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 S +++W +G I+ KYD G L I + DEGEY+C + + A Sbjct: 485 SPPPNIIWLLNGHEIQTDNVKYDLTNDG----LAIHDIRKSDEGEYTCEISGSNVKATAN 540 Query: 1102 VVELPPEIIT-RLQNQKVNKGNKATFEIELTK---GDALVRWFKDGSEIQFSNHIQLTID 1157 V +I +QK G F E+ K A V W+ + + + + L I Sbjct: 541 VQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRKASVEWYLNDVLLPVNGNSGLRIS 600 Query: 1158 -GKKQKLKIYDCDLDDAGEYSCEV 1180 +K L I D+ GEY C V Sbjct: 601 RNRKGSLIIRQVGPDNTGEYRCRV 624 Score = 40.3 bits (90), Expect = 0.57 Identities = 47/219 (21%), Positives = 90/219 (41%), Gaps = 19/219 (8%) Query: 729 TGEKEPPQ-VIEPLKSMIVRQG-ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDT 786 T E EP Q +I+ K + V G + +++ G+P P I W N ++ K D Sbjct: 451 TSELEPSQKLIKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTN 510 Query: 787 HSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKE 846 + I +K DEG YT + S A + + + E ++ I Sbjct: 511 DGLAIHDIRK-SDEGEYTCEISGSNVKATANVQVNGDSLIEYGP-----ADQKSLIGTNV 564 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEII----SPSETITQNFDGENIELVITNVDSEIDSG 902 + + ++ R S+ WY N+ ++ + I++N G L+I V + ++G Sbjct: 565 EFSCEVAKEYVRK--ASVEWYLNDVLLPVNGNSGLRISRNRKG---SLIIRQVGPD-NTG 618 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE 941 +Y+C + + + A + I +EK + ++ E Sbjct: 619 EYRCRVTVDGREENASAMLQI-IEKPAMPERVRAELHNE 656 Score = 37.9 bits (84), Expect = 3.0 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 T+ DKP P G ++ S+ + WDEP N +I Y+V Y+ E KN + Sbjct: 1769 TLEDKPGPVGILRFSDVLMDSVKVSWDEPSQP-NGNVIGYIVNYKGYRMQE--EFKNEDQ 1825 Query: 1436 TQTS 1439 +TS Sbjct: 1826 QRTS 1829 >UniRef50_Q13203 Cluster: Myosin-binding protein H; n=35; Tetrapoda|Rep: Myosin-binding protein H - Homo sapiens (Human) Length = 477 Score = 96.3 bits (229), Expect = 8e-18 Identities = 68/302 (22%), Positives = 136/302 (45%), Gaps = 21/302 (6%) Query: 1282 EVVEFPP-KIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSID 1339 E +E P ++ + R+ I++ G V L + +Q P+P W N + + + + D Sbjct: 167 ENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGD 226 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 S L I+ + +D+G Y+L + A +++ +++KP PP +L++ + + Sbjct: 227 QDSI-LFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAAL 285 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 W P++TGN+ ++ Y+V+ + T +W +V + T +I +L +SY FR ++ N Sbjct: 286 QWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENL 345 Query: 1459 VDISDASETTEYYKVIKETKI-------------QSPTVEKPLKNITTEPNEDIELTCIF 1505 +S ++ T+ I++ I ++P+ +PL + T+ P +L C Sbjct: 346 CGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSV 405 Query: 1506 GGVPQPKVTWYRDGKKL----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET 1561 P+PK+ W ++ ++ K + + Y C A N GE Sbjct: 406 RASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASV 465 Query: 1562 SC 1563 C Sbjct: 466 DC 467 Score = 72.5 bits (170), Expect = 1e-10 Identities = 43/167 (25%), Positives = 81/167 (48%), Gaps = 5/167 (2%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 +VG+ + +G P P+ W NG+ L++ + ++ T ++ S++ I+ +RS S +Y Sbjct: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQR-VSMRTGDQDSILFIRSAQRSDSGRYE 245 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + + + + V +KP P + + ++ + ++W PP D G EL Y ++ Sbjct: 246 LTVRVEDLEAKAVIDILVIEKPGPPSS-IRLLDVWGCNAALQWTPPQDTGNTELLGYMVQ 304 Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFS 1750 K + +W V ++R T C I L Y FRV ++N G S Sbjct: 305 KADKKTGQWFTV--LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349 Score = 61.3 bits (142), Expect = 3e-07 Identities = 37/155 (23%), Positives = 69/155 (44%), Gaps = 7/155 (4%) Query: 1379 DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW--ISVKNITKT 1436 D PS P + ++ SSS+ + W+ PE G + YV+E +EW +S + + T Sbjct: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP---LKNITT 1493 Q +++NL + R AV+ + + + I++P + P + Sbjct: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI--RENIEAPKIRVPRHLRQTYIR 186 Query: 1494 EPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKAT 1528 + E + L F G P+P+ TW +G L + + + Sbjct: 187 QVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVS 221 Score = 56.8 bits (131), Expect = 6e-06 Identities = 36/114 (31%), Positives = 53/114 (46%), Gaps = 4/114 (3%) Query: 492 IDKLPVFEKPTS---EEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA 548 I K + KP + S AP F + L + G + Q C V P+P+I W + Sbjct: 361 IQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKM 420 Query: 549 IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 I+ + ++ + V TL IR+ P D+G +TC A N G AS L V+A Sbjct: 421 EIQGNPKYRAL-SEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKA 473 Score = 46.8 bits (106), Expect = 0.007 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 PS P + + +S SVT+ W PE G + Y++E W + V + Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVP 1966 + N+ D+ + R+SA ++ G P Q + + ++ P Sbjct: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172 Score = 45.6 bits (103), Expect = 0.015 Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 4/150 (2%) Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR--EI 1678 + T E + + E R + A T+S T P P+++ ++ Sbjct: 24 VPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTAST-ATKPAPPSEDVPSAPLLLTLDDV 82 Query: 1679 SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYM 1738 S SVT+ W+PP G L L Y +E + W+ V+ V ++ L +++ Sbjct: 83 SSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFL 142 Query: 1739 FRVIAQNPVGFS-EALESEPIVIKTALDVP 1767 RV A + G A+ +PI I+ ++ P Sbjct: 143 LRVSAVSSAGAGPPAMLDQPIHIRENIEAP 172 Score = 45.2 bits (102), Expect = 0.020 Identities = 65/299 (21%), Positives = 114/299 (38%), Gaps = 31/299 (10%) Query: 1765 DVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEG-KKWKXXXXXXXXX 1823 DVPS + + SV ++W P E+ G + Y +E+ +EG +W Sbjct: 69 DVPSAPLLLTLDD-VSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMV 127 Query: 1824 AR--IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS--QPRNFVVSESTS 1879 + ++ L++ + R+ A + G P D I I + + P PR+ Sbjct: 128 TQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRH-------- 179 Query: 1880 RSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE-NIKEKDEIIF 1938 L+ T G + + K +WT G ++ + ++D I+F Sbjct: 180 ----LRQTYIRQVGETVNLQIPFQGKPKPQATWTHN---GHALDSQRVSMRTGDQDSILF 232 Query: 1939 RISAENTVGVSLPTESQSVRLEKHATV-------PSPPTAPLEIRMVGSNIVMTSWGTPE 1991 SA+ + + LE A + P PP++ + + G N + W P+ Sbjct: 233 IRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAAL-QWTPPQ 291 Query: 1992 WDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 G LLGY + D W V + + I DL ++Y R+++ N GLS Sbjct: 292 DTGNTELLGYMVQKADKKTGQWFTVLE-RYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349 Score = 43.6 bits (98), Expect = 0.061 Identities = 30/94 (31%), Positives = 40/94 (42%), Gaps = 4/94 (4%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSI 789 E P +PL G S L V +P+P I W KN ++ P S+ ++ Sbjct: 380 EAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTL 439 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 I KP D GVYT KA N G A + V+ Sbjct: 440 EIRKPSPF-DSGVYTCKAINVLGEASVDCRLEVK 472 Score = 43.2 bits (97), Expect = 0.081 Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 7/106 (6%) Query: 1963 ATVPSPPT-----APLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 AT P+PP+ APL + + V S+ V SW PE G L GY + + + W+ Sbjct: 60 ATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVP 119 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKV 2061 V + + +R+L+ +++R+ A + G P D+P + Sbjct: 120 VSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165 Score = 42.7 bits (96), Expect = 0.11 Identities = 18/67 (26%), Positives = 36/67 (53%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSS 1655 + P P++IW KN +++ + +Y +++ + I++ S YT +A N G +S Sbjct: 405 VRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEAS 464 Query: 1656 VEVTLKV 1662 V+ L+V Sbjct: 465 VDCRLEV 471 Score = 39.9 bits (89), Expect = 0.75 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 7/99 (7%) Query: 733 EPPQVIEP--LKSMIVRQ-GESVILSAQVVGNPRPTITWCKNNKPVKA-LPTKSDGDTHS 788 E P++ P L+ +RQ GE+V L G P+P TW N + + + GD S Sbjct: 170 EAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDS 229 Query: 789 ITILKPKKVKDEGVY--TLKAENSEGIAETSAVITVEEP 825 I ++ + D G Y T++ E+ E A ++ +E+P Sbjct: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVID-ILVIEKP 267 Score = 39.1 bits (87), Expect = 1.3 Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 6/96 (6%) Query: 634 PTFSKKPKAQYVDE-GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P+F++ P A + G L C + A P+P I W+ EI + E + C Sbjct: 382 PSFTQ-PLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGV---C 437 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK 728 + L+I F G YT A+N GEAS+ L++K Sbjct: 438 T-LEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472 >UniRef50_Q9BMN8 Cluster: Tyrosine-protein phosphatase Lar-like precursor; n=6; Caenorhabditis|Rep: Tyrosine-protein phosphatase Lar-like precursor - Caenorhabditis elegans Length = 2200 Score = 96.3 bits (229), Expect = 8e-18 Identities = 117/527 (22%), Positives = 203/527 (38%), Gaps = 39/527 (7%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL------KTAKATYENRXXX 1535 P +E + E + ++C G P+ KV W RD L + + +T N Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCV---VGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y+CIA N G + V +++ P + + VG + Sbjct: 211 MIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINL 270 Query: 1593 TAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 T V G P P V W K + +D T +V+ + ++ + + +T A + G Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPS---TAPIGKNVLTLTHVESTEN--FTCVAVSALG 325 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLE--LTKYAIEKHEPDN 1710 T+ + P P +++ ++ ESV I WKPP + + + Y ++ E + Sbjct: 326 NIEATTTVIAKELPPPPVN-IVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGRS 384 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 +R + ++ + I L Y F V + PVG LES P+ +T P+ Sbjct: 385 SRGKTMETLENSL---VIDGLVAFQTYEFTVRSAGPVGV--GLESLPVEAQTKPSKPATA 439 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-----IKQEGKKWK-XXXXXXXXXA 1824 ++ +S+ + W P E+ G I YKV + ++WK Sbjct: 440 PVSPQARSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMT 498 Query: 1825 RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTL 1884 I L ++ Y R+ A+N G S P ++ +T+ P QP V SR + L Sbjct: 499 TINGLEPDSRYFVRVIAQNSEGDS-PLST--LVTVATRQGIPGQPPMLTVKALDSRRMQL 555 Query: 1885 KWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 W +P + SP+ Y + + T G+ K +T+ +H + + FR++A + Sbjct: 556 TWDKPLYS--SPVVGYTVRYNTSDGE---KELTLTSPHEKHVVTGLHPDKYYYFRVAAYS 610 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPE 1991 G TE + A++P + S V W PE Sbjct: 611 DRGQGEFTEPMISK--TIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655 Score = 66.9 bits (156), Expect = 6e-09 Identities = 76/301 (25%), Positives = 131/301 (43%), Gaps = 36/301 (11%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E P +P + V + S I CR P P + W G+ I IS+ + Sbjct: 44 EDDPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISI---KSLA 100 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV----LKIKTGEKEP---PQV-IEP- 740 S L+ V + TVV+ + + + P+V L + +K P PQ+ + P Sbjct: 101 TGLSTLRFERVS--LDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPS 158 Query: 741 LKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKP------ 794 LKS V QG++ +S +V G+PR + W ++ P L ++DG TI P Sbjct: 159 LKS--VEQGKTAYVSCRVRGDPRAKVLWLRDLIP---LDIRADGRYSVSTIGNPGALMIQ 213 Query: 795 -KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQ-EITVKEKGTIKL 852 + +D+G Y A N+ G+A + A + PP F + + + V G I L Sbjct: 214 HAREEDQGKYECIARNTLGVAHSKAANLY---VKVRRVPPYFSYKLERQYVVGVGGNINL 270 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 P+P + W + + ++ + G+N+ L +T+V+S + ++ CVA ++ Sbjct: 271 TCVAVGYPMPRVFWKKTDLMVLDDPSTAP--IGKNV-LTLTHVES---TENFTCVAVSAL 324 Query: 913 G 913 G Sbjct: 325 G 325 Score = 64.5 bits (150), Expect = 3e-08 Identities = 206/967 (21%), Positives = 345/967 (35%), Gaps = 115/967 (11%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQL-TIDGKKQK 1162 P ++ R + V +K +F G+ L V W +G I N I + ++ Sbjct: 47 PARLVVRPDSSTVVDESKISFFCR-ADGNPLPSVIWRVNGKSITDHNRISIKSLATGLST 105 Query: 1163 LKIYDCDLDD-AGEYSCEVGNSKCTAILTVEE----PSINFTLRLPEFILVPA------N 1211 L+ LDD A SC N ++ P + P+ L P+ Sbjct: 106 LRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQG 165 Query: 1212 TDAYLTVEIP-DETLDVTWYKKKSVIEDTE--KFTLISDVKKRTLIIRKCTEDDQCEYTC 1268 AY++ + D V W + ++ ++++ + L+I+ E+DQ +Y C Sbjct: 166 KTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYEC 225 Query: 1269 VLLDA-----KSTTKLKVEVVEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWI 1322 + + L V+V PP ER+Y + G ++ L +P P W Sbjct: 226 IARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWK 285 Query: 1323 VNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 ++ T P K+ LT+ VE+T+ + + G+ + V + P Sbjct: 286 KTDLMVLDDPSTAPI--GKNV-LTLTHVESTEN--FTCVAVSALGNIEATTTVIAKELPP 340 Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 PP + + S S+ I W P+ N I YVV Y+ + +E S + KT +++N Sbjct: 341 PPVNIVVSSVTSESVVITWKPPKY--NEAINKYVVNYR-LKYSEGRSSRG--KTMETLEN 395 Query: 1443 -LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 L + F+ Y E V +TK P P+ N D + Sbjct: 396 SLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPAT-APVSPQARSLNRD-SI 453 Query: 1502 TCIFGGVPQPK--VTWYR---DGKKLKTAKATYENRXXXXXXXXXX------XXXXXYKC 1550 +G QP +T Y+ + T ++ + Sbjct: 454 LVKWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDSRYFVRV 513 Query: 1551 IAFNDHGEVETSCVVGIQ-------QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPE 1603 IA N G+ S +V + Q P++T+ D ++ D+ L ++ + G Sbjct: 514 IAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGY---- 569 Query: 1604 VIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK-V 1662 + Y N + +KE +T+ + V+ + + + + G + + K + Sbjct: 570 TVRY---NTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTI 626 Query: 1663 YDKPSKPEGPVIMREISRESVTIEWKPP-------------LDDGGLELTKYA-IEKHEP 1708 P V S +SV I WK P ++ LE +K A +E E Sbjct: 627 ASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTANLESVEY 686 Query: 1709 DNNRWIKVADVDR-------DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIK 1761 D + + +DR D +Y + L Y V A G+ ES V+K Sbjct: 687 DEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGP--ESSIRVVK 744 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITW-FPSEKNGG----SPIIDYKVE---IKQEGKKW 1813 T DVPS SV +TW P+ NG +D V + ++G K Sbjct: 745 TLEDVPSAPRNFNAELT-SATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKK 803 Query: 1814 KXXXXXXXXXA--RIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRN 1871 + + L NT Y FR+ A N G IT G PP P Sbjct: 804 RIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQG---IPPEAPE- 859 Query: 1872 FVVSESTSRS-----VTLKWTEPESN-GGSPITNYIIEFKTV-KGKSWTKIVTVGGSVHE 1924 +VS S R ++W P+ +PI Y + + S+ K TV G+ Sbjct: 860 -IVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRM-VGSNIV 1983 I + ++AEN G SQ+ V SP P++++ V + Sbjct: 919 TTISGLWMGVVYDVLLAAENREG-----RSQNATETIATPVGSPDGEPIDVQYEVMKGKI 973 Query: 1984 MTSWGTP 1990 + SW P Sbjct: 974 VVSWRPP 980 Score = 61.3 bits (142), Expect = 3e-07 Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 20/205 (9%) Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEF--KTVKGKSWTKIV 1916 I K L PP P N VVS TS SV + W P+ N I Y++ + K +G+S ++ Sbjct: 334 IAKELPPP--PVNIVVSSVTSESVVITWKPPKYN--EAINKYVVNYRLKYSEGRS-SRGK 388 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGV---SLPTESQSVRLEKHATVPSPPTAPL 1973 T+ + I+ + F + + VGV SLP E+Q+ + K AT P P A Sbjct: 389 TMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQT-KPSKPATAPVSPQA-- 445 Query: 1974 EIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNTLKF--NIRD 2030 R + + ++ WG E G + GY + D+ T E + D + +F I Sbjct: 446 --RSLNRDSILVKWGPCEQPNGL-ITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTING 502 Query: 2031 LSENHTYMIRIYARNEIGLSEPLES 2055 L + Y +R+ A+N G PL + Sbjct: 503 LEPDSRYFVRVIAQNSEG-DSPLST 526 Score = 60.1 bits (139), Expect = 7e-07 Identities = 100/451 (22%), Positives = 177/451 (39%), Gaps = 53/451 (11%) Query: 1641 SKYTIE--ASNTAGTSSVEVTLKVYDKPSKPEGPVIM--REISRESVTIEWKPPLDDGGL 1696 S+Y + A N+ G S + + V + P P ++ + + + + W PL Sbjct: 507 SRYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRMQLTWDKPLYSS-- 564 Query: 1697 ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESE 1756 + Y + + D + + + E + + L+ + Y FRV A + G E +E Sbjct: 565 PVVGYTVRYNTSDGEKELTLTSPH---EKHVVTGLHPDKYYYFRVAAYSDRGQGEF--TE 619 Query: 1757 PIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVE-IKQEGKKW- 1813 P++ KT +P ++SV I W P +K + Y++ + E K Sbjct: 620 PMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKTA 679 Query: 1814 -----KXXXXXXXXXARIQKLSI-----NTTY---QFRIYARNEI----GTSLPYTSDDK 1856 + + + ++S+ T+Y Y+ EI T Y + Sbjct: 680 NLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESS 739 Query: 1857 ITIGKTLTP-PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK----- 1910 I + KTL PS PRNF +++ SV L W P + G+ + Y+ + V G+ Sbjct: 740 IRVVKTLEDVPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEK 799 Query: 1911 -SWTKIVTVGGSVHEHC-IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSP 1968 S +IV + S + ++++ E FR++A N G +E +S+ T P Sbjct: 800 GSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSI-----ITQGIP 854 Query: 1969 PTAPLEIRMVGSN------IVMTSWGTPEW-DGGAPLLGYNIAIR-DVTKTMWMEVGKVD 2020 P AP EI V + + W P+ P+ YN+ +R +++ VD Sbjct: 855 PEAP-EIVSVSLDRDEPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVD 913 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 L I L Y + + A N G S+ Sbjct: 914 GTDLSTTISGLWMGVVYDVLLAAENREGRSQ 944 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 519 KHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDD-DNVATLVIREVFPED 577 K G T C+V G PR ++ W R + D + N L+I+ ED Sbjct: 160 KSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREED 219 Query: 578 AGTFTCVAKNAAGFASS 594 G + C+A+N G A S Sbjct: 220 QGKYECIARNTLGVAHS 236 Score = 39.9 bits (89), Expect = 0.75 Identities = 100/460 (21%), Positives = 164/460 (35%), Gaps = 35/460 (7%) Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG---TSSVEVTLKVYDKPSKPEGP 1672 D+ + + TS + + +L S + T+ AS G SS+ V + D PS P Sbjct: 698 DRMSVVVPSDATSYV-LSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRN- 755 Query: 1673 VIMREI-SRESVTIEWKPPLDDGGLELTKYA----IEKHEPDNNRWIKVADV---DRDVE 1724 E+ S SV + W P G L Y + EP + K V D Sbjct: 756 -FNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKR 814 Query: 1725 TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESV 1784 + + L+ N EY FR+ A N G E E + I+ T P D V Sbjct: 815 YFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSII--TQGIPPEAPEIVSVSLDRDEPPV 872 Query: 1785 Y--ITW-FPSEKNGGSPIIDYKVEIKQEG-----KKWKXXXXXXXXXARIQKLSINTTYQ 1836 I W P K +PI Y + ++ +G K K I L + Y Sbjct: 873 VARIEWKMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTT-ISGLWMGVVYD 931 Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGS 1895 + A N G S T +G +P +P + V E + + W P E Sbjct: 932 VLLAAENREGRSQNATETIATPVG---SPDGEPID-VQYEVMKGKIVVSWRPPSEEKRNG 987 Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 IT+Y + + V E + + +F+++A G+ + Sbjct: 988 NITSYKAILSAMDATADRYEQPVPAPSTSSTFE-VNVRRAYLFKVAAATMKGIGPYSPVL 1046 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR-DVTKTMWM 2014 ++ + A V P +E + +V + + + D + R D K + Sbjct: 1047 TINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQL 1106 Query: 2015 EVGKVD-VNTLKFN-IRDLSENHTYMIRIYA-RNEIGLSE 2051 V +D N +F + DL+ + Y + A +N + L+E Sbjct: 1107 PVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNE 1146 Score = 37.5 bits (83), Expect = 4.0 Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 13/96 (13%) Query: 510 PIFVEKLRPKHTPD-GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P F KL ++ G + C GYP P++ W ++T + M DD + A + Sbjct: 250 PYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFW-KKTDL--------MVLDDPSTAPI 300 Query: 569 ---VIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 V+ E FTCVA +A G +TT +I + Sbjct: 301 GKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAK 336 >UniRef50_A4JYL6 Cluster: Sid4; n=4; Clupeocephala|Rep: Sid4 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 381 Score = 95.9 bits (228), Expect = 1e-17 Identities = 80/330 (24%), Positives = 152/330 (46%), Gaps = 27/330 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+ S +P+ V G + +CR+ + +P + K +N+ + + + Sbjct: 22 PSVSVRPRTAAVRLGETVSFQCRVTSGAQPVMLEWRKINNQPLGDNVKIGPDG------A 75 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESV 752 VL I NV+ +G Y +A N +G++++ L +K PP+V + P + +R GE V Sbjct: 76 VLTIANVRLNNQGGYRCIATNAQGKSTVTANLSVK----HPPKVRVSPAGPLTLRVGEIV 131 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 L V G PRP+++W + + + D+ + + ++ G+Y +A+N EG Sbjct: 132 TLDCSVSGKPRPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGEG 191 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 +AE VE E A P ++ E+T E ++ + + + +P ++W +++ Sbjct: 192 LAEGE----VELVMEGGAFPQASVSE-TELTAVEGQSVSMHCQASGSPAAVLSW---SKL 243 Query: 873 ISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVK 932 +P DG L ++NV + DSG Y C A+++ G S A V ++V+ + Sbjct: 244 RAPLPW-QHKVDGGT--LTLSNVGRQ-DSGQYICNATSALGFSE--AYVQLEVDSPPYAT 297 Query: 933 HLQKSYETEEGKTVILEC--QTSHTVSTKW 960 L + G + L+C SH + +W Sbjct: 298 VLTEVVVLRVGDALRLQCLAHGSHPIRFRW 327 Score = 60.9 bits (141), Expect = 4e-07 Identities = 69/278 (24%), Positives = 114/278 (41%), Gaps = 28/278 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L+C + P P ++W+ + + E +S +S + L++T G Sbjct: 128 GEIVTLDCSVSGKPRPSVSWI-RRQAGGETELVSTTTDST-----TSLQVTMATAENAGM 181 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y A N EG A + L ++ G V E + + +G+SV + Q G+P ++ Sbjct: 182 YVCRAQNGEGLAEGEVELVMEGGAFPQASVSETELTAV--EGQSVSMHCQASGSPAAVLS 239 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 W K P LP + D ++T+ + +D G Y A ++ G +E + V+ P Sbjct: 240 WSKLRAP---LPWQHKVDGGTLTLSNVGR-QDSGQYICNATSALGFSEAYVQLEVDSPP- 294 Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SITWYR-NNEIISPSETITQNFDG 885 + E+ V G + + P W R +S T+ DG Sbjct: 295 -------YATVLTEVVVLRVGDALRLQCLAHGSHPIRFRWMRVGGACMSTGAESTK--DG 345 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 L I + S DSG YKC A+N G S +RVT+ Sbjct: 346 L---LRIPQLKSS-DSGTYKCTATNHVGSSEALSRVTV 379 Score = 49.2 bits (112), Expect = 0.001 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 3/78 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V +C V G PRP ++W R+ A + + D+ +L + E+AG + C Sbjct: 128 GEIVTLDCSVSGKPRPSVSWIRRQA---GGETELVSTTTDSTTSLQVTMATAENAGMYVC 184 Query: 584 VAKNAAGFASSTTELIVE 601 A+N G A EL++E Sbjct: 185 RAQNGEGLAEGEVELVME 202 Score = 39.5 bits (88), Expect = 0.99 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 7/81 (8%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 +G +V CQ G P ++W + A + +Q D TL + V +D+G + Sbjct: 220 EGQSVSMHCQASGSPAAVLSWSKLRAPLP----WQHKVDG---GTLTLSNVGRQDSGQYI 272 Query: 583 CVAKNAAGFASSTTELIVEAP 603 C A +A GF+ + +L V++P Sbjct: 273 CNATSALGFSEAYVQLEVDSP 293 Score = 38.7 bits (86), Expect = 1.7 Identities = 50/232 (21%), Positives = 81/232 (34%), Gaps = 19/232 (8%) Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 +I N++ N+ +R A N S T V K++ P +T E Sbjct: 78 TIANVRLNNQGGYRCIATNA---QGKSTVTANLSVKHPPKVRV----SPAGPLTLRVGEI 130 Query: 1499 IELTCIFGGVPQPKVTWYR--DGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + L C G P+P V+W R G + + T ++ Y C A N Sbjct: 131 VTLDCSVSGKPRPSVSWIRRQAGGETELVSTTTDSTTSLQVTMATAENAGMYVCRAQNGE 190 Query: 1557 G--EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 G E E V+ P ++S ++ G + G P + W +KL Sbjct: 191 GLAEGEVELVMEGGAFPQASVSETELTAVE--GQSVSMHCQASGSPAAVLSW----SKLR 244 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP 1666 + K + + + R S +Y A++ G S V L+V P Sbjct: 245 APLPWQ--HKVDGGTLTLSNVGRQDSGQYICNATSALGFSEAYVQLEVDSPP 294 Score = 36.7 bits (81), Expect = 7.0 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 4/127 (3%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKI-VDYEREYRIKRGSDVTLLVD 1310 L I ++Q Y C+ +A+ + + + V+ PPK+ V ++ G VTL Sbjct: 77 LTIANVRLNNQGGYRCIATNAQGKSTVTANLSVKHPPKVRVSPAGPLTLRVGEIVTLDCS 136 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 P+P+ WI + + + + DS + SL + +AG+Y R +N G A+ Sbjct: 137 VSGKPRPSVSWI-RRQAGGETELVSTTTDS-TTSLQVTMATAENAGMYVCRAQNGEGLAE 194 Query: 1371 VEMNVTI 1377 E+ + + Sbjct: 195 GEVELVM 201 >UniRef50_Q90478 Cluster: Neural cell adhesion molecule L1.1; n=9; Cyprinidae|Rep: Neural cell adhesion molecule L1.1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1197 Score = 95.9 bits (228), Expect = 1e-17 Identities = 158/779 (20%), Positives = 289/779 (37%), Gaps = 47/779 (6%) Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 Y + RG +TL + P P W + TK +++ L I V +D G Sbjct: 187 YLVLRGQTLTLQCIPEGLPTPEVHWDRIDSALSP-NRTKKLYNNRW--LQIDNVLESDDG 243 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y N+ VT+ P P + + + D + + I + Sbjct: 244 EYVCTARNSENSVKHHYTVTVEAAPYWTRSPEE-HLYAPGETVRLDCKADGIPAPNITWS 302 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 + + T+ + ++ + + N++ + + ++ AVN+ S + + E Sbjct: 303 INGVPVSGTDVDPRRRVSSGKLILSNVEFSDTAVYQCEAVNK----HGSILINTHVHVVE 358 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDG-KKLKTAKATYENRXX 1534 Q T ++ L T + + L C G P PK+ W D L AK + Sbjct: 359 LPAQILTPDERLYQATA--GQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGS 416 Query: 1535 XXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTA 1594 Y C + + V + K V N + + T Sbjct: 417 LKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYT- 475 Query: 1595 VIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 V + P V W K+G+K+ N E +++ +++ Y+ E S T + Sbjct: 476 VDHNLKSPTVQWNKDGHKITASTS-NDKYHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSD 534 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE---PDNN 1711 + + V DKP P+ + ++ R SVTI W P +++ +T+Y IE +E PD Sbjct: 535 TASGYITVQDKPDPPQSLKLSEKMER-SVTISWMPSVENNS-PVTEYVIEMNEGETPDEG 592 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 +W K V +D++++ + + +Y F++ A N +G S ES + T P Sbjct: 593 QWQKYRSVSQDIDSW--RSICSYSKYHFQIRAVNSIGTSAPTESS-LSYSTPAAKPDTNP 649 Query: 1772 XXXXXXXIDNESVYITWFPSEKNG-GSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQ 1827 D +S+ I+W ++ P YKV G W + Sbjct: 650 ENVMTLSTDPKSMIISWQEMDRRQFNGPGFQYKVFWRRAADSGAHW-TESSVSNPPLMVN 708 Query: 1828 KLSINTTYQFRIYARNEIGTS-LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 +++ ++ A N++G + P T I P P V+E SV ++W Sbjct: 709 NTGTFVSFEIKVQAVNDLGAAPEPLT---VIGYSGEDFPLEAPSALSVTELQKTSVMVRW 765 Query: 1887 T--EPESNGGSPITNYIIEFKTVKGKSW-TKIVTVGGSVHEHCIE---NIKEKDEIIFRI 1940 + PES G + Y I + +KG W T V S + IE + EK + Sbjct: 766 SPVRPESVRGH-LLGYKI-YLRMKGSQWETPGRAVSSSGNPTVIEVPADAAEKIVSDLQF 823 Query: 1941 SAENTVGV-SLPTESQSVRLEKHATVPSPPTAP---LEIRMVGSNIVMTSWGTPEWDGGA 1996 ++ T+ + + ++ + E+ + P P L + + W P G Sbjct: 824 YSDYTLTITAFNSKGEGPHSEESFSTPEGAPGPVLFLPFDSPSESEITLRWEAPHKPNG- 882 Query: 1997 PLLGYNIAIRDVT--KTMWMEVGKVDVNTL-KFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + GY + ++V V +D+ + +F +++L+ Y + ARN+ G P Sbjct: 883 EIRGYLLQYQEVVIGSESPQHVESIDLPAVTEFTLKNLNPESRYTFHLSARNDAGDGAP 941 Score = 90.2 bits (214), Expect = 5e-16 Identities = 107/446 (23%), Positives = 169/446 (37%), Gaps = 31/446 (6%) Query: 1044 TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILR--DESCTAEVT 1101 T +V W+R + P + K + R L I N D+GEY C R + S T Sbjct: 206 TPEVHWDRIDSALSPNRTKKLYNNRW----LQIDNVLESDDGEYVCTARNSENSVKHHYT 261 Query: 1102 V-VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGK 1159 V VE P + G + + A + W +G + ++ + Sbjct: 262 VTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTD-VDPRRRVS 320 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPAN----TDAY 1215 KL + + + D Y CE N + ++ + LP IL P A Sbjct: 321 SGKLILSNVEFSDTAVYQCEAVNKHGSILINTHV----HVVELPAQILTPDERLYQATAG 376 Query: 1216 LTVEIPDETLDVTWYKKKSVIEDTEKF---TLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 TV + T K I D+ IS +L I +E+D YTC + + Sbjct: 377 QTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSLKISNVSEEDSNRYTCSVSE 436 Query: 1273 AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA---FPQPNDEWIVNS-KII 1328 + VEV+ KIV + + RGSD L Y P +W + KI Sbjct: 437 TNKSISADVEVLN-RTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDGHKIT 495 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 + K SL + V+ D GIY + +T+ DKP PP Sbjct: 496 ASTSNDK--YHEIEGSLKVLDVQMEDMGIYSCEVSTTLDSDTASGYITVQDKPDPPQSLK 553 Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTT---EWISVKNITKTQTSIQNLKT 1445 + E S+ I W P NS + YV+E E +T +W +++++ S +++ + Sbjct: 554 LSEKMERSVTISW-MPSVENNSPVTEYVIEMNEGETPDEGQWQKYRSVSQDIDSWRSICS 612 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYY 1471 S Y F+ AVN + S +E++ Y Sbjct: 613 YSKYHFQIRAVNSIGTSAPTESSLSY 638 Score = 73.7 bits (173), Expect = 5e-11 Identities = 86/342 (25%), Positives = 138/342 (40%), Gaps = 34/342 (9%) Query: 860 PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 P P + W R + +SP+ T N L I NV E D G+Y C A NS H Sbjct: 205 PTPEVHWDRIDSALSPNRTKKLY---NNRWLQIDNV-LESDDGEYVCTARNSENSVKH-- 258 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISG--MDHREI 975 T+ VE + + + G+TV L+C+ + W N +SG +D R Sbjct: 259 HYTVTVEAAPYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSINGVPVSGTDVDPRRR 318 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKL-----QDFEVKE 1030 + G+ D V +C ++ S ++ + E ++ + ++ Sbjct: 319 VSSGK---LILSNVEFSDTAVYQCEAVNKHGSILINTHVHVVELPAQILTPDERLYQATA 375 Query: 1031 KDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 +L+ S + WE I K G ++ I N S D Y+C Sbjct: 376 GQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNGSLK---ISNVSEEDSNRYTC 432 Query: 1090 ILRD--ESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL----VRWFKDG 1143 + + +S +A+V V+ +I+ QN V +G+ A + T L V+W KDG Sbjct: 433 SVSETNKSISADVEVLN-RTKIVGPPQNLHVIRGSDAILHCKYTVDHNLKSPTVQWNKDG 491 Query: 1144 SEI--QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS 1183 +I SN I+G LK+ D ++D G YSCEV + Sbjct: 492 HKITASTSNDKYHEIEG---SLKVLDVQMEDMGIYSCEVSTT 530 Score = 66.5 bits (155), Expect = 8e-09 Identities = 101/421 (23%), Positives = 163/421 (38%), Gaps = 39/421 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + L+C +P P++ W + P N + + ++ L+I NV + +G Sbjct: 192 GQTLTLQCIPEGLPTPEVHWDRIDSALSP--NRTKKLYNNRW-----LQIDNVLESDDGE 244 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y A N E + T E P P + + GE+V L + G P P IT Sbjct: 245 YVCTARNSENSVKHHYTV---TVEAAPYWTRSP-EEHLYAPGETVRLDCKADGIPAPNIT 300 Query: 768 WCKNNKPVKALPTKSDGDTHS-ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W N PV S IL + D VY +A N G + + V E Sbjct: 301 WSINGVPVSGTDVDPRRRVSSGKLILSNVEFSDTAVYQCEAVNKHGSILINTHVHVVELP 360 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSET-ITQNFDG 885 + P R + T + T+ L R +P+P I W + I + S I+Q +G Sbjct: 361 AQILTPD---ERLYQATAGQ--TVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQTTNG 415 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 L I+NV SE DS Y C S +++ ++V T + ++ G Sbjct: 416 ---SLKISNV-SEEDSNRYTC----SVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSD 467 Query: 946 VILECQ--TSHTV---STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 IL C+ H + + +W + +I+ + E D+G+ C Sbjct: 468 AILHCKYTVDHNLKSPTVQWNKDGHKITASTSNDKYHE-IEGSLKVLDVQMEDMGIYSCE 526 Query: 1001 VK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAIL---EVEINSETADVVWE-RDG 1053 V D +T++ + + P+ + L+ E E+ V I VE NS + V E +G Sbjct: 527 VSTTLDSDTASGYITVQDKPDPPQSLKLSEKMERSVTISWMPSVENNSPVTEYVIEMNEG 586 Query: 1054 E 1054 E Sbjct: 587 E 587 Score = 64.5 bits (150), Expect = 3e-08 Identities = 83/375 (22%), Positives = 148/375 (39%), Gaps = 25/375 (6%) Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802 S +V +G+++ L G P P + W + + + TK + + I + D+G Sbjct: 186 SYLVLRGQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLYNNRWLQIDNVLE-SDDGE 244 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y A NSE + +TVE P + +E T++L + P P Sbjct: 245 YVCTARNSENSVKHHYTVTVE-------AAPYWTRSPEEHLYAPGETVRLDCKADGIPAP 297 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 +ITW N +S ++ + +L+++NV+ D+ Y+C A N G V Sbjct: 298 NITWSINGVPVSGTDVDPRRRVSSG-KLILSNVEFS-DTAVYQCEAVNKHGSILINTHVH 355 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-WYHNKKEISGMDHREIIQEGRX 981 + + ++ Y+ G+TV+L+C+T + K + I + + +I Q Sbjct: 356 VVELPAQILTPDERLYQATAGQTVMLDCRTFGSPLPKIHWEILDSIPALSNAKISQT-TN 414 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKE-TIPEFIRKLQDFEVKEKDVAILE--- 1037 D C V + S V+ + + Q+ V AIL Sbjct: 415 GSLKISNVSEEDSNRYTCSVSETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKY 474 Query: 1038 -VEINSETADVVWERDG-EIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC----IL 1091 V+ N ++ V W +DG +I N E G ++ L + + D G YSC L Sbjct: 475 TVDHNLKSPTVQWNKDGHKITASTSNDKYHEIEGSLKVL---DVQMEDMGIYSCEVSTTL 531 Query: 1092 RDESCTAEVTVVELP 1106 ++ + +TV + P Sbjct: 532 DSDTASGYITVQDKP 546 Score = 58.8 bits (136), Expect = 2e-06 Identities = 73/317 (23%), Positives = 130/317 (41%), Gaps = 24/317 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P +++ P+ G + L+C+ IP P+I W G VP V + + Sbjct: 268 PYWTRSPEEHLYAPGETVRLDCKADGIPAPNITWSING---VPVSGTDV--DPRRRVSSG 322 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESV 752 L ++NV+ Y AVN+ G S+ I + E P Q++ P + + G++V Sbjct: 323 KLILSNVEFSDTAVYQCEAVNKHG--SILINTHVHVVEL-PAQILTPDERLYQATAGQTV 379 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--ILKPKKVKDEGVYTLKAENS 810 +L + G+P P I W + + ++P S+ T LK V +E S Sbjct: 380 MLDCRTFGSPLPKIHW----EILDSIPALSNAKISQTTNGSLKISNVSEEDSNRYTCSVS 435 Query: 811 EGIAETSAVITVEEPTEENAEPP-LFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 E SA + V T+ P L + R + + K T+ + P++ W ++ Sbjct: 436 ETNKSISADVEVLNRTKIVGPPQNLHVIRGSDAILHCKYTVDHNLK-----SPTVQWNKD 490 Query: 870 NEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVT 929 I+ S + + + E L + +V E D G Y C S + + +T+ +K Sbjct: 491 GHKITASTSNDKYHEIEG-SLKVLDVQME-DMGIYSCEVSTTLDSDTASGYITVQ-DKPD 547 Query: 930 FVKHLQKSYETEEGKTV 946 + L+ S + E T+ Sbjct: 548 PPQSLKLSEKMERSVTI 564 Score = 49.2 bits (112), Expect = 0.001 Identities = 68/328 (20%), Positives = 123/328 (37%), Gaps = 23/328 (7%) Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPSPP------GKPNILEIDSSSINICWDEPENTGN 1409 G Y+ N G A V V + +P P K E+ S++ C + P+++ Sbjct: 43 GTYRCYAANELGTA-VSNLVHLTTEPVPSLAKVKKQKRRAYEVGESAVLRC-NPPKSSVT 100 Query: 1410 STIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS---YRFRAYAVNEVDISDASE 1466 I + +++ I E +++ NL N S Y A+ +N I Sbjct: 101 PKIHWMDMQFHHIPLNERVTISR--DGNLYFANLIANDSRDDYTCNAHYINASIILPKEP 158 Query: 1467 TTEYY----KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 + Y V+K + + + + + L CI G+P P+V W R L Sbjct: 159 MSIYVTPSNSVVKNRRAKLHHPAGARSSYLVLRGQTLTLQCIPEGLPTPEVHWDRIDSAL 218 Query: 1523 --KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDI 1580 K Y NR Y C A N V+ V ++ P T S E+ Sbjct: 219 SPNRTKKLYNNR-WLQIDNVLESDDGEYVCTARNSENSVKHHYTVTVEAAPYWTRSPEE- 276 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 + G+ + +GIP P + W NG + + + + + + + + ++ S + Sbjct: 277 -HLYAPGETVRLDCKADGIPAPNITWSINGVPV-SGTDVDPRRRVSSGKLILSNVEFSDT 334 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + Y EA N G+ + + V + P++ Sbjct: 335 AVYQCEAVNKHGSILINTHVHVVELPAQ 362 Score = 43.2 bits (97), Expect = 0.081 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T+ +C EG P P++ W R + + P++ ++Y N L I V D G + C Sbjct: 192 GQTLTLQCIPEGLPTPEVHWDRIDSALSPNRTKKLY----NNRWLQIDNVLESDDGEYVC 247 Query: 584 VAKNAAGFASSTTELIVEA 602 A+N+ + VEA Sbjct: 248 TARNSENSVKHHYTVTVEA 266 >UniRef50_O44328 Cluster: Receptor tyrosine phosphatase; n=6; Eumetazoa|Rep: Receptor tyrosine phosphatase - Hirudo medicinalis (Medicinal leech) Length = 2051 Score = 95.5 bits (227), Expect = 1e-17 Identities = 103/464 (22%), Positives = 172/464 (37%), Gaps = 24/464 (5%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISD-ASETTEYYKVIKETKIQSPTVEKPLKNITTEPNED 1498 ++ +K R+ A N V + D S Y P + K + E Sbjct: 93 VEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVERYRS 152 Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXXYKCIAFNDH 1556 + C G P+P +W +D ++ + Y+CIA N H Sbjct: 153 TVMACSGKGNPEPTFSWLKDFIPIEFTPVRFSVMPTGALQLLNSTYSYEGKYECIAENSH 212 Query: 1557 GEVETSCVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 G + + + I + +V G +T + G P P ++W +N L Sbjct: 213 GVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMWKRNNLDLS 272 Query: 1615 NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVI 1674 + + T V+R++ + + S+ YT A + GT+S V +KV P KP + Sbjct: 273 HRSNNH---SHGTGVLRLEGI--TESANYTCHAISELGTASHVVQVKVNVLP-KPPSSLW 326 Query: 1675 MREISRESVTIEWKPPLDDG-GLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNE 1733 + E+S +V ++W P D + ++ PDN + + DV D + I +L Sbjct: 327 ITEVSPNTVHLKWSPGNSDPVDSYIIRFRPRYSHPDN--FTEFTDVGSDTTDHHIARLIR 384 Query: 1734 NCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEK 1793 EY FRV A N +G S + S P+ + T VP + +V +T + Sbjct: 385 YTEYEFRVYAVNKLGRSAS--STPVDVVTGELVPGSEPPNVRARPVSGTTVVVTMGRTNH 442 Query: 1794 NGGSPIIDYKV-----EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTS 1848 YKV + W + L N TY + A +G Sbjct: 443 CATGSYKGYKVYYTGQPVVTPVSLWTLHIVENSHLTTLTNLKENHTYTISVLAFTSVGDG 502 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESN 1892 P + D + + P QP NF+ +S S+ ++W P SN Sbjct: 503 -PLS--DNVQVFTRPGVPDQPTNFLGESVSSTSIHIQWDRPASN 543 Score = 84.2 bits (199), Expect = 4e-14 Identities = 76/297 (25%), Positives = 126/297 (42%), Gaps = 19/297 (6%) Query: 637 SKKPKA-QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVL 695 S+ P+ Q V EG+ C +V P P++ W ++ + + H SVL Sbjct: 32 SRPPRVVQKVMEGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVL 91 Query: 696 KITNVKKFQEGTYTVVAVNREGEAS-LPIVLKIKTGEKEP-----PQVIEPLKSMIVRQG 749 ++ VKK EG Y A N G + L + T + +P P+++ K V + Sbjct: 92 RVEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYT-KNDPIPAGFPEILVHPKLGSVERY 150 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAE 808 S +++ GNP PT +W K+ P++ P + S T ++ +L EG Y AE Sbjct: 151 RSTVMACSGKGNPEPTFSWLKDFIPIEFTPVRFSVMPTGALQLLN-STYSYEGKYECIAE 209 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 NS G+ + V + PP F V G++ L + +P P I W R Sbjct: 210 NSHGVTNSQQATLV---LKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMWKR 266 Query: 869 NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 NN +S + G + ++ +S +Y C A + G +SH +V ++V Sbjct: 267 NNLDLSHRSNNHSHGTG------VLRLEGITESANYTCHAISELGTASHVVQVKVNV 317 Score = 75.8 bits (178), Expect = 1e-11 Identities = 114/487 (23%), Positives = 184/487 (37%), Gaps = 42/487 (8%) Query: 1596 IEGIPPPEVIWYKNGNKLEN----DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 + G P PE+ WY KLE+ I T SV+R++ +K+ +Y EA N Sbjct: 53 VVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVLRVEPVKKRDEGRYECEAHNGV 112 Query: 1652 GTSS-VEVTLKVYDKPSK-PEG-PVIMREISRESVTIEWKPPL---DDGGLELTKYAIEK 1705 G V L VY K P G P I+ SV + G E T ++ Sbjct: 113 GVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVERYRSTVMACSGKGNPEPTFSWLKD 172 Query: 1706 HEPDNNRWIKVADVDRDV-ETYCIQKLNENCEY--MFRVIAQNPVGFSEALESEPIVIKT 1762 P I+ V V T +Q LN Y + IA+N G + + ++ +V+K Sbjct: 173 FIP-----IEFTPVRFSVMPTGALQLLNSTYSYEGKYECIAENSHGVTNSQQAT-LVLKA 226 Query: 1763 ALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXX 1822 P + S+ +T S GSP + + K+ Sbjct: 227 RRIPPHFSALPDNAEVVHGGSLNLTCIAS----GSP--EPFIMWKRNNLDLSHRSNNHSH 280 Query: 1823 XARIQKLS-INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRS 1881 + +L I + + +A +E+GT+ + K P P + ++E + + Sbjct: 281 GTGVLRLEGITESANYTCHAISELGTA------SHVVQVKVNVLPKPPSSLWITEVSPNT 334 Query: 1882 VTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVHEHCIENIKEKDEIIFR 1939 V LKW+ S+ P+ +YII F+ ++T+ VG +H I + E FR Sbjct: 335 VHLKWSPGNSD---PVDSYIIRFRPRYSHPDNFTEFTDVGSDTTDHHIARLIRYTEYEFR 391 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLL 1999 + A N +G S S V + VP + R V V+ + G Sbjct: 392 VYAVNKLGRS--ASSTPVDVVTGELVPGSEPPNVRARPVSGTTVVVTMGRTNHCATGSYK 449 Query: 2000 GYNIAI--RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 GY + + V + + + N+ + +L ENHTY I + A +G PL + Sbjct: 450 GYKVYYTGQPVVTPVSLWTLHIVENSHLTTLTNLKENHTYTISVLAFTSVG-DGPLSDNV 508 Query: 2058 PFKVIPG 2064 PG Sbjct: 509 QVFTRPG 515 Score = 63.7 bits (148), Expect = 5e-08 Identities = 74/328 (22%), Positives = 120/328 (36%), Gaps = 35/328 (10%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKP---SQDFQMYYDDDNVATLVIREVFPEDAG 579 +G+ F C V G P P++TW+ ++ Q + + N++ L + V D G Sbjct: 43 EGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNLSVLRVEPVKKRDEG 102 Query: 580 TFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKK 639 + C A N G + + +D I G P Sbjct: 103 RYECEAHNGVGVPDRVSFNLSVYTKND--------------------PIPAGFPEILVH- 141 Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 PK V+ ++ C PEP +WL ++ +P E V M L++ N Sbjct: 142 PKLGSVERYRSTVMACSGKGNPEPTFSWL---KDFIPIEFTPVRFSV---MPTGALQLLN 195 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 EG Y +A N G + + + PP + V G S+ L+ Sbjct: 196 STYSYEGKYECIAENSHGVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIAS 255 Query: 760 GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 G+P P I W +NN L +S+ +H +L+ + + + YT A + G A S V Sbjct: 256 GSPEPFIMWKRNNLD---LSHRSNNHSHGTGVLRLEGITESANYTCHAISELGTA--SHV 310 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEK 847 + V+ L+I TV K Sbjct: 311 VQVKVNVLPKPPSSLWITEVSPNTVHLK 338 Score = 51.6 bits (118), Expect = 2e-04 Identities = 63/280 (22%), Positives = 116/280 (41%), Gaps = 22/280 (7%) Query: 1722 DVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDN 1781 D+ + + L + Y V N G E S+ I++KT D+P +++ Sbjct: 690 DLRSATLHDLKKFTAYKIWVAGYNRAG--EGPLSDVIIVKTEEDIPGEPKRVKVEA-LNS 746 Query: 1782 ESVYITWFP---SEKNGGSP--IIDYKVEIKQEGKKWKXXXXXXXXXAR----IQKLSIN 1832 SV++ W E NG ++ Y + E +K++ + I LS + Sbjct: 747 TSVHLEWKAPQDGEHNGDIKGYVVFYTELDENEEEKFEPVRSDPLSSHQTELTIGGLSPS 806 Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS--ESTSRSVTLKWTEPE 1890 T YQF++ A G + K+ + PS P+ F +S + + V + W +P+ Sbjct: 807 TLYQFQVCAYTRKGDG-DKSKSKKVKTKAAV--PSPPKGFTLSLMKEENPIVLVTWQDPK 863 Query: 1891 SNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSL 1950 + G I Y++ F VKG+S + G++H +++ F+I+A+N VG Sbjct: 864 FSHGV-IEGYLVAFG-VKGESHVEERRFNGNIHRFITPFLEKGATYEFKIAAKNAVGYG- 920 Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTP 1990 E + + PS L ++G++ + W P Sbjct: 921 --EYATEVITTPDGAPSGAPQNLSAAVLGAHTIRLHWDPP 958 Score = 47.6 bits (108), Expect = 0.004 Identities = 84/387 (21%), Positives = 148/387 (38%), Gaps = 43/387 (11%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQ----LTIDGKK 1160 PP ++ QKV +GN ATF + K + W+ +++ + Q + Sbjct: 34 PPRVV-----QKVMEGNMATFWCGVVGKPAPEMTWYHMNRKLESFTYQQSSRKIFTHHNL 88 Query: 1161 QKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVP--ANTD 1213 L++ D G Y CE N + + L+V + PE ++ P + + Sbjct: 89 SVLRVEPVKKRDEGRYECEAHNGVGVPDRVSFNLSVYTKNDPIPAGFPEILVHPKLGSVE 148 Query: 1214 AYLTVEI-------PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEY 1266 Y + + P+ T +W K IE T S + L + T + +Y Sbjct: 149 RYRSTVMACSGKGNPEPTF--SWLKDFIPIEFTP--VRFSVMPTGALQLLNSTYSYEGKY 204 Query: 1267 TCVLLDAKSTTK-----LKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 C+ ++ T L ++ PP + G + L P+P W Sbjct: 205 ECIAENSHGVTNSQQATLVLKARRIPPHFSALPDNAEVVHGGSLNLTCIASGSPEPFIMW 264 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 N+ + H + + L ++ + T++ Y + G A + V + P Sbjct: 265 KRNNLDLS---HRSNNHSHGTGVLRLEGI--TESANYTCHAISELGTASHVVQVKVNVLP 319 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTG--NSTIIYYVVEYQEIDT-TEWISVKNITKTQT 1438 PP I E+ +++++ W P N+ +S II + Y D TE+ V + T T Sbjct: 320 KPPSSLWITEVSPNTVHLKWS-PGNSDPVDSYIIRFRPRYSHPDNFTEFTDVGSDT-TDH 377 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDAS 1465 I L + Y FR YAVN++ S +S Sbjct: 378 HIARLIRYTEYEFRVYAVNKLGRSASS 404 Score = 39.1 bits (87), Expect = 1.3 Identities = 54/235 (22%), Positives = 93/235 (39%), Gaps = 18/235 (7%) Query: 1826 IQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLK 1885 I +L T Y+FR+YA N++G S T D +T G+ L P S+P N + +V + Sbjct: 379 IARLIRYTEYEFRVYAVNKLGRSASSTPVDVVT-GE-LVPGSEPPNVRARPVSGTTVVVT 436 Query: 1886 WTEPESNGGSPITNYIIEFK----TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRIS 1941 Y + + WT + + + H + N+KE + Sbjct: 437 MGRTNHCATGSYKGYKVYYTGQPVVTPVSLWT--LHIVENSHLTTLTNLKENHTYTISVL 494 Query: 1942 AENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGY 2001 A +VG P S +V++ VP PT L V S + W P + ++ Y Sbjct: 495 AFTSVGDG-PL-SDNVQVFTRPGVPDQPTNFLG-ESVSSTSIHIQWDRPASNN---IVRY 548 Query: 2002 NIAIRD--VTKTMWMEVG--KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 + D +++G + D + + + DL+ + Y + + A E G P Sbjct: 549 KLRYMDSNTRSNFSVDIGRKRQDQRIIWYLLTDLAASTVYHMTLSAVAEGGEGPP 603 Score = 37.1 bits (82), Expect = 5.3 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 4/98 (4%) Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILE---IDSSSINICWDEP-ENTGNSTII 1413 +K+ +N G+ + V +P G P L + + +I + WD P + + I Sbjct: 909 FKIAAKNAVGYGEYATEVITTPDGAPSGAPQNLSAAVLGAHTIRLHWDPPVKKLRHGVIQ 968 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRF 1451 Y V Y E D + N T+T + L+ + SY F Sbjct: 969 MYEVVYCESDDPGQDVMVNTTETSLVVDKLEADRSYTF 1006 >UniRef50_UPI0000DB6D93 Cluster: PREDICTED: similar to CG32387-PB, isoform B; n=3; Apocrita|Rep: PREDICTED: similar to CG32387-PB, isoform B - Apis mellifera Length = 792 Score = 95.1 bits (226), Expect = 2e-17 Identities = 111/535 (20%), Positives = 209/535 (39%), Gaps = 40/535 (7%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP F+++ + G I+L C IP P W E V + E ++ Sbjct: 188 VPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWF---RESVTGTAMIFNSER-IYAR 243 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 VL + + + G Y A N G + + + I + + P + + V G+ Sbjct: 244 AGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIH---LVP-QQVTVDLGKD 299 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPT---KSDGDTHSITILKPKKVKDEGVYTLKAE 808 V G P P I W K+ PV + K G+ S + D+G+Y A+ Sbjct: 300 AEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAK 359 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N + + +A + + + P + +F E T++ ++ L T NP P +W Sbjct: 360 NDYEMVQATAELRLGDAA------PQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTL 413 Query: 869 NNEIISPSET--ITQ--NFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + + ++ I Q G+ I V +V D G+Y+C A+N K H AR ++ Sbjct: 414 DGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAANRMAKVHHSAR--LN 471 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXX 982 + + V+ + +Y G+T +++C + S W + K + +E+ G Sbjct: 472 IYGLPHVRPM-GNYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNG--T 528 Query: 983 XXXXXXXXXXDVGVIKCIVKDQE---TSTMLVVKETIPEFIRKLQ---DFEVKEKDVAIL 1036 D G C K+++ S + ++ +P I + + + + Sbjct: 529 LVLHHVDRSTDHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVHVVC 588 Query: 1037 EVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC 1096 V + W +DG + + + + T+ H+ G Y+C+ +++ Sbjct: 589 VVSEGDSPLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHN-GNYTCVASNDAA 647 Query: 1097 TAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELTKGDA--LVRWFKDGSEI 1146 T +V +PP I N+ +++G +A + KGD + W KDG I Sbjct: 648 ETSRTASLLVHVPPTIAPFSFNKDLSEGVRAQVTCMVEKGDPPFTIAWSKDGEAI 702 Score = 61.7 bits (143), Expect = 2e-07 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 8/187 (4%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKA--TYENRXXXXXXXXXXX 1543 +P+ N E + C G P +TW +DGK L T++ + N Sbjct: 479 RPMGNYAAVAGETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPNGTLVLHHVDRST 538 Query: 1544 XXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISN--EDIKQKHKVGDEWLVTAVIEGIP 1600 Y C A N G ++ V + ++ P I + +I++ +V +V V EG Sbjct: 539 DHGAYTCTAKNKQGRSDSQTVHIEVKVPPKIDPFSFPANIQEGARVH---VVCVVSEGDS 595 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P ++ W K+G L + + E + I+ +H+ YT ASN A +S +L Sbjct: 596 PLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAAETSRTASL 655 Query: 1661 KVYDKPS 1667 V+ P+ Sbjct: 656 LVHVPPT 662 Score = 51.6 bits (118), Expect = 2e-04 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T + P F E++ P G T+ C +G P P WFR+ ++ + F Sbjct: 182 TDPHTPVPPRFNERVSPAPIRTGETIVLSCISQGIPPPMYLWFRE-SVTGTAMIFNSERI 240 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDH 607 LV++ EDAG + C A N AG E+ + + LS H Sbjct: 241 YARAGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIH 286 Score = 47.2 bits (107), Expect = 0.005 Identities = 69/301 (22%), Positives = 116/301 (38%), Gaps = 40/301 (13%) Query: 639 KPKAQYVD-EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKI 697 +P Y G +++C + P I W G+ ++P + + V + Sbjct: 479 RPMGNYAAVAGETTVIKCPVAGFPIASITWEKDGK-VLPTSRRQEVFPNGTLVLHHVDRS 537 Query: 698 TNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILS 755 T+ G YT A N++G + S + +++K PP+ I+P +++G V + Sbjct: 538 TD-----HGAYTCTAKNKQGRSDSQTVHIEVKV----PPK-IDPFSFPANIQEGARVHVV 587 Query: 756 AQVVGNPRPT-ITWCKNNKPVKALPTKSD--GDTHSITILKPKKVKDEGVYTLKAENSEG 812 V P ITW K+ +P+ + T + G+ +++ G YT A N Sbjct: 588 CVVSEGDSPLKITWLKDGRPLNSTETTTHHIGEYDLTLMIQSATTAHNGNYTCVASNDAA 647 Query: 813 IAETSAVITVEEPTEENAEPPLFIN-------RFQEITVKEKGTIKLVARVTRN------ 859 +A + V P P N R Q + EKG +++ Sbjct: 648 ETSRTASLLVHVPP---TIAPFSFNKDLSEGVRAQVTCMVEKGDPPFTIAWSKDGEAIAG 704 Query: 860 PVPSITWYRNNEIISPSETITQ------NFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P P+ + N I P T T N D + +VI V S SG+Y C+A NS Sbjct: 705 PSPAAAGFGNTGITGPRHTQTPAGLRVTNIDAHSSTIVIERV-SAAHSGNYTCMARNSVA 763 Query: 914 K 914 + Sbjct: 764 E 764 Score = 44.4 bits (100), Expect = 0.035 Identities = 49/219 (22%), Positives = 82/219 (37%), Gaps = 14/219 (6%) Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEP--- 1495 S+ + SSYR R V+ V D E++ Y +++ T +P + + ++ P Sbjct: 148 SVTSSDAQSSYRCRT--VHRVT-GDTVESSSYARLVV-TDPHTPVPPRFNERVSPAPIRT 203 Query: 1496 NEDIELTCIFGGVPQPKVTWYRDG----KKLKTAKATYENRXXXXXXXXXXXXXXXYKCI 1551 E I L+CI G+P P W+R+ + ++ Y Y C Sbjct: 204 GETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSERIYARAGVLVLQSARAEDAGRYVCH 263 Query: 1552 AFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 A N G V I I + + + +G + + G P P + W K+G Sbjct: 264 ANNTAGSEMVELEVSIISSLSIHLVPQQVTV--DLGKDAEFQCSVTGQPIPVIFWTKDGL 321 Query: 1612 KL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASN 1649 + E+ + T S +RI + R Y A N Sbjct: 322 PVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKN 360 Score = 44.0 bits (99), Expect = 0.046 Identities = 23/75 (30%), Positives = 34/75 (45%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +F+C V G P P I W + + S + ++ +TL I V +D G + C Sbjct: 297 GKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQC 356 Query: 584 VAKNAAGFASSTTEL 598 AKN +T EL Sbjct: 357 FAKNDYEMVQATAEL 371 Score = 42.3 bits (95), Expect = 0.14 Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 6/82 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREV-FPEDAGTFT 582 G T +C V G+P ITW + ++ S+ +++ + TLV+ V D G +T Sbjct: 489 GETTVIKCPVAGFPIASITWEKDGKVLPTSRRQEVFPN----GTLVLHHVDRSTDHGAYT 544 Query: 583 CVAKNAAGFA-SSTTELIVEAP 603 C AKN G + S T + V+ P Sbjct: 545 CTAKNKQGRSDSQTVHIEVKVP 566 Score = 41.1 bits (92), Expect = 0.33 Identities = 42/204 (20%), Positives = 76/204 (37%), Gaps = 12/204 (5%) Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL-----KTAKATYENRX 1533 I S ++ + +T + +D E C G P P + W +DG + +K T + Sbjct: 280 ISSLSIHLVPQQVTVDLGKDAEFQCSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGS 339 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y+C A ND+ V+ + + + + + I+Q + G + Sbjct: 340 TLRISSVVRDDKGMYQCFAKNDYEMVQATAELRLGD-AAPQLLYKFIEQTIQPGPSVSLK 398 Query: 1594 AVIEGIPPPEVIWYKNGNKL-ENDK----EYNITTKEKTSVIRIKELKRSHSSKYTIEAS 1648 + G P P W +G L +ND+ +Y + S + I + +Y A+ Sbjct: 399 CIATGNPTPHFSWTLDGFPLPQNDRFMIGQYVTVHGDVISHVNISVVHVEDGGEYRCTAA 458 Query: 1649 NTAGTSSVEVTLKVYDKPS-KPEG 1671 N L +Y P +P G Sbjct: 459 NRMAKVHHSARLNIYGLPHVRPMG 482 Score = 38.3 bits (85), Expect = 2.3 Identities = 18/81 (22%), Positives = 42/81 (51%), Gaps = 6/81 (7%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKN---GNKLENDKEYNITTKEKTSVIRIKELKRSHSS 1641 + G+ +++ + +GIPPP +W++ G + + E + V+ ++ + + Sbjct: 202 RTGETIVLSCISQGIPPPMYLWFRESVTGTAMIFNSE---RIYARAGVLVLQSARAEDAG 258 Query: 1642 KYTIEASNTAGTSSVEVTLKV 1662 +Y A+NTAG+ VE+ + + Sbjct: 259 RYVCHANNTAGSEMVELEVSI 279 Score = 36.3 bits (80), Expect = 9.2 Identities = 46/231 (19%), Positives = 92/231 (39%), Gaps = 15/231 (6%) Query: 1105 LPPEIITRLQNQKVNKGNKATFEIELTKG--DALVRWFKD---GSEIQFSNHIQLTIDGK 1159 +PP R+ + G +++G + WF++ G+ + F++ I + Sbjct: 188 VPPRFNERVSPAPIRTGETIVLSC-ISQGIPPPMYLWFRESVTGTAMIFNSE---RIYAR 243 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI-NFTLRL-PEFILVPANTDAYLT 1217 L + +DAG Y C N+ + ++ +E I + ++ L P+ + V DA Sbjct: 244 AGVLVLQSARAEDAGRYVCHANNTAGSEMVELEVSIISSLSIHLVPQQVTVDLGKDAEFQ 303 Query: 1218 VEIPDETLDVTWYKKKS--VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS 1275 + + + V ++ K V E + I+ TL I DD+ Y C + Sbjct: 304 CSVTGQPIPVIFWTKDGLPVGESASGRSKITGNDGSTLRISSVVRDDKGMYQCFAKNDYE 363 Query: 1276 TTKLKVE--VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVN 1324 + E + + P+++ E I+ G V+L P P+ W ++ Sbjct: 364 MVQATAELRLGDAAPQLLYKFIEQTIQPGPSVSLKCIATGNPTPHFSWTLD 414 >UniRef50_Q501U7 Cluster: Ttnl protein; n=2; Danio rerio|Rep: Ttnl protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 384 Score = 95.1 bits (226), Expect = 2e-17 Identities = 76/356 (21%), Positives = 155/356 (43%), Gaps = 33/356 (9%) Query: 491 KIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAII 550 ++ P+ + PT ++++ P F +L+ + V+ ++ G +P I+W + + Sbjct: 35 RVKSPPMVKSPTPKDKTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNL 94 Query: 551 KPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS----D 606 ++++ ++ A L I + D+G +TC A+N+ G S+ L ++A + + Sbjct: 95 SQGGKYEIF-EEHGSAHLEIYDADLSDSGVYTCTAQNSVGSVSTNCTLTIQARTTAAALE 153 Query: 607 HGSEMT---VXXXXXXXXXXXXADI-----------LEGIPPTFSKKPKAQYVDEGSDIL 652 SE+T V +I P+F +P +Q V+EG ++ Sbjct: 154 GKSELTEEIVKKENTYEEVQSYTEIKASKTQMTVSATHSGSPSFLVQPHSQNVNEGQNVT 213 Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 C + P P++ WL I N+ ++ +++ L+I N G +TV A Sbjct: 214 FTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVY----TLEIHNATIEDSGKFTVKA 269 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N+ G+ S L + + PP++ + + + G+ + ++ G+P P I W + Sbjct: 270 KNKFGQCSATASLNVLS---VPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSG 326 Query: 773 KPVKA------LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 K + + L ++ D ++ I K+ D G YTLK N G T+ +++ Sbjct: 327 KTLSSKEESGRLQIENSQDVTTLFISAVKET-DAGAYTLKLSNEFGSDTTTVNVSI 381 Score = 62.5 bits (145), Expect = 1e-07 Identities = 40/137 (29%), Positives = 64/137 (46%), Gaps = 5/137 (3%) Query: 464 EEKGWVPAQYLMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPD 523 E K + + + EN Y + +Q K K + S S +P F+ + ++ + Sbjct: 153 EGKSELTEEIVKKENTYEE-VQSYTEIKASKT---QMTVSATHSGSPSFLVQPHSQNVNE 208 Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V F C++ G P P++ W + A+I + + ++ NV TL I ED+G FT Sbjct: 209 GQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKL-SRSKNVYTLEIHNATIEDSGKFTV 267 Query: 584 VAKNAAGFASSTTELIV 600 AKN G S+T L V Sbjct: 268 KAKNKFGQCSATASLNV 284 Score = 59.7 bits (138), Expect = 9e-07 Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 6/167 (3%) Query: 1217 TVEIPDE-TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--A 1273 T EI E + +V W K +VI T L TL I T +D ++T + Sbjct: 215 TCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVKAKNKFG 274 Query: 1274 KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKH 1333 + + + V+ PPKI R+ I+ G +++ + P P EW + K + + Sbjct: 275 QCSATASLNVLSVPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEE 334 Query: 1334 T-KPSIDSKS--ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 + + I++ +L I V+ TDAG Y L+L N G +NV+I Sbjct: 335 SGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSI 381 Score = 50.0 bits (114), Expect = 7e-04 Identities = 43/187 (22%), Positives = 83/187 (44%), Gaps = 10/187 (5%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKI 1165 P + + +Q VN+G TF E+T + V W KD + I +++++L+ L+I Sbjct: 195 PSFLVQPHSQNVNEGQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEI 254 Query: 1166 YDCDLDDAGEYSCEVGN--SKCTAILTVEEPSINFTLR-LPEFILV-PANTDAYLTVEIP 1221 ++ ++D+G+++ + N +C+A ++ S+ + P I + P + Sbjct: 255 HNATIEDSGKFTVKAKNKFGQCSATASLNVLSVPPKIEAAPRDISIEPGKVLSVACAFTG 314 Query: 1222 DETLDVTWY---KKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKST 1276 D T + W K S E++ + + + TL I E D YT L + T Sbjct: 315 DPTPCIEWSHSGKTLSSKEESGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDT 374 Query: 1277 TKLKVEV 1283 T + V + Sbjct: 375 TTVNVSI 381 Score = 47.2 bits (107), Expect = 0.005 Identities = 41/183 (22%), Positives = 72/183 (39%), Gaps = 8/183 (4%) Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 VK E Y E + E A T + ++ P F+ + V E + + Sbjct: 163 VKKENTY----EEVQSYTEIKASKTQMTVSATHSGSPSFLVQPHSQNVNEGQNVTFTCEI 218 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 T P P + W ++N +IS + + + L I N E DSG + A N G+ S Sbjct: 219 TGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIE-DSGKFTVKAKNKFGQCS 277 Query: 917 HGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHRE 974 A + + + ++ + E GK + + C + T +W H+ K +S + Sbjct: 278 ATASLNV-LSVPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEESG 336 Query: 975 IIQ 977 +Q Sbjct: 337 RLQ 339 Score = 46.4 bits (105), Expect = 0.009 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 3/122 (2%) Query: 822 VEEPT-EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 V+ PT ++ P F ++I+ +KL +++ + PSI+W ++ + +S Sbjct: 42 VKSPTPKDKTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQGGKYE 101 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 + + L I + D DSG Y C A NS G S +TI + T KS T Sbjct: 102 IFEEHGSAHLEIYDADLS-DSGVYTCTAQNSVGSVSTNCTLTIQA-RTTAAALEGKSELT 159 Query: 941 EE 942 EE Sbjct: 160 EE 161 Score = 42.3 bits (95), Expect = 0.14 Identities = 34/174 (19%), Positives = 65/174 (37%), Gaps = 10/174 (5%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAK----ATYENRXXXXXXXXXXXXXXXYKCIA 1552 +++ TC G P P+V W +D + + +N + A Sbjct: 210 QNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVKA 269 Query: 1553 FNDHGEVETSCVVGI-QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N G+ + + + P I + DI + G V G P P + W +G Sbjct: 270 KNKFGQCSATASLNVLSVPPKIEAAPRDI--SIEPGKVLSVACAFTGDPTPCIEWSHSGK 327 Query: 1612 KLENDKE---YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 L + +E I + + + I +K + + YT++ SN G+ + V + + Sbjct: 328 TLSSKEESGRLQIENSQDVTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSI 381 Score = 41.9 bits (94), Expect = 0.19 Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 6/98 (6%) Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE-----NR 1532 K P+ LK+I+ + ++LT G +P ++W +DGK L YE Sbjct: 50 KTSKPSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQG-GKYEIFEEHGS 108 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQK 1570 Y C A N G V T+C + IQ + Sbjct: 109 AHLEIYDADLSDSGVYTCTAQNSVGSVSTNCTLTIQAR 146 Score = 41.5 bits (93), Expect = 0.25 Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 2/95 (2%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G T I G P PEV W K+ + ++ + + I S K+T++ Sbjct: 209 GQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEIHNATIEDSGKFTVK 268 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE 1681 A N G S +L V P K E R+IS E Sbjct: 269 AKNKFGQCSATASLNVLSVPPKIE--AAPRDISIE 301 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK- 793 P LK + V L+ ++ G+ +P+I+W K+ K + + H L+ Sbjct: 54 PSFSTELKDISASADTIVKLTVKLSGDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLEI 113 Query: 794 -PKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 + D GVYT A+NS G T+ +T++ T Sbjct: 114 YDADLSDSGVYTCTAQNSVGSVSTNCTLTIQART 147 Score = 40.3 bits (90), Expect = 0.57 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 3/79 (3%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 P T L++ + ++L+ GD + W KDG + ++ + L+ Sbjct: 54 PSFSTELKDISASADTIVKLTVKLS-GDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLE 112 Query: 1165 IYDCDLDDAGEYSCEVGNS 1183 IYD DL D+G Y+C NS Sbjct: 113 IYDADLSDSGVYTCTAQNS 131 Score = 40.3 bits (90), Expect = 0.57 Identities = 20/71 (28%), Positives = 33/71 (46%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T + G P + W K+G L +Y I + ++ + I + S S YT A N+ Sbjct: 73 LTVKLSGDLKPSISWMKDGKNLSQGGKYEIFEEHGSAHLEIYDADLSDSGVYTCTAQNSV 132 Query: 1652 GTSSVEVTLKV 1662 G+ S TL + Sbjct: 133 GSVSTNCTLTI 143 Score = 38.3 bits (85), Expect = 2.3 Identities = 19/94 (20%), Positives = 37/94 (39%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P + + G +VT + P P EW+ ++ +I + K S +L I Sbjct: 195 PSFLVQPHSQNVNEGQNVTFTCEITGEPSPEVEWLKDNAVISITSNMKLSRSKNVYTLEI 254 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 D+G + ++ +N G ++ +L P Sbjct: 255 HNATIEDSGKFTVKAKNKFGQCSATASLNVLSVP 288 Score = 37.9 bits (84), Expect = 3.0 Identities = 22/98 (22%), Positives = 42/98 (42%), Gaps = 1/98 (1%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP P+ ++ G + + C P P I W G+ + E S ++ + Sbjct: 287 VPPKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSSKEE-SGRLQIENSQD 345 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT 729 + L I+ VK+ G YT+ N G + + + I++ Sbjct: 346 VTTLFISAVKETDAGAYTLKLSNEFGSDTTTVNVSIRS 383 Score = 36.3 bits (80), Expect = 9.2 Identities = 14/43 (32%), Positives = 23/43 (53%) Query: 1482 PTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKT 1524 P +E ++I+ EP + + + C F G P P + W GK L + Sbjct: 289 PKIEAAPRDISIEPGKVLSVACAFTGDPTPCIEWSHSGKTLSS 331 >UniRef50_Q4SR20 Cluster: Chromosome 11 SCAF14528, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 11 SCAF14528, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 786 Score = 95.1 bits (226), Expect = 2e-17 Identities = 103/436 (23%), Positives = 189/436 (43%), Gaps = 41/436 (9%) Query: 785 DTHSITILKPKKVKDEGVYTLKAENS----EGIAETSAVITVEEPTEENAEPPLFINRFQ 840 +T S+ I K ++ D G YT N+ + ++ + ++ + EP + ++ + Sbjct: 26 ETGSLYIAKVER-SDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPE 84 Query: 841 EITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 + ++ +KL NPVP I+W R + I PS+ +N N L I N E D Sbjct: 85 SVPAAKESAVKLECFALGNPVPEISWRRTSGIPFPSKVKMKN---SNAVLEIPNFQQE-D 140 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVST 958 +G Y+CVA N GK++ R++ K +++ + + + E + EC+ + S Sbjct: 141 AGTYECVAENRRGKNAARGRLSFHA-KPHWLQTMADTALSIEA-NLFWECKANGKPKPSY 198 Query: 959 KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014 W N ++++ + R I G D G+ +C+ +++ +S L+V Sbjct: 199 SWLKNGEQVAA-EGRIQIDNG---ALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLA 254 Query: 1015 TIPEFIRKLQDFEVKEKDVAILEVEINSET---ADVVWERDGEIIKPKKNKYDFEKRGHI 1071 + P F + +K + + + +E E A +W++ EI+ P+ + + G I Sbjct: 255 SPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEIL-PRTERINLLPNGTI 313 Query: 1072 RKLYIRNTSVHDEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEI 1128 + I N + D G Y+CI +++ TA T ++ P I R N ++ G A Sbjct: 314 K---IANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPC 370 Query: 1129 ELTKGDAL---VRWFKDGSEIQF---SNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178 ++ AL W +G I F NH + L I + L G+Y C Sbjct: 371 QIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDT 430 Query: 1179 EVGNSKCTAILTVEEP 1194 +V + +AIL V+ P Sbjct: 431 DVESLSTSAILVVKGP 446 Score = 81.0 bits (191), Expect = 3e-13 Identities = 125/535 (23%), Positives = 197/535 (36%), Gaps = 51/535 (9%) Query: 1499 IELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXX-XXXXXXXXXYKCIAFNDHG 1557 ++L C G P P+++W R +K +N Y+C+A N G Sbjct: 94 VKLECFALGNPVPEISWRRTSGIPFPSKVKMKNSNAVLEIPNFQQEDAGTYECVAENRRG 153 Query: 1558 EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDK 1617 + + KP + D + W A G P P W KNG ++ + Sbjct: 154 KNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKA--NGKPKPSYSWLKNGEQVAAEG 211 Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP---SKPEGPVI 1674 I + I L S S Y A N G L V P SK + Sbjct: 212 RIQIDN----GALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASPPNFSKSPLKAL 267 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIE---KHEPDN---NRWIKVADVDR-DVETY- 1726 ++ S VT+E KP + L K E + E N N IK+A+ R D +Y Sbjct: 268 LKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPNGTIKIANATRQDAGSYT 327 Query: 1727 CIQKLN-ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY 1785 CI K +++ P + + I++ + +P V Sbjct: 328 CIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQIAFDPAL------DVS 381 Query: 1786 ITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEI 1845 +W NG +ID++ ++G ++ I+ + ++ ++ I Sbjct: 382 FSW---AFNG--QLIDFQ----RDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCL----I 428 Query: 1846 GTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK 1905 T + S I + K PP P V E T + L WT P + GSPIT YII+ + Sbjct: 429 DTDVESLSTSAILVVKG--PPGPPDKVTVEEITDSTAQLSWT-PGRDNGSPITGYIIQAR 485 Query: 1906 TVKGKSWTKIVTV----GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEK 1961 T W + TV G++ + + E FR+ A N VG+ P+ + S + Sbjct: 486 TPFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPSPA-SAKTRT 544 Query: 1962 HATVPSPPTAPLEIRMVG---SNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMW 2013 ++P TAP ++ G S +V+T PE GY IA R + W Sbjct: 545 EDSIPD--TAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPLGMVTW 597 Score = 79.0 bits (186), Expect = 1e-12 Identities = 101/435 (23%), Positives = 174/435 (40%), Gaps = 39/435 (8%) Query: 695 LKITNVKKFQEGTYTVVAVNR-EGEASL----PIVLKIK--TGEKEPPQVIEPLKSMIVR 747 L I V++ G YT V N G+ L P+VL+ GE EP + +S+ Sbjct: 30 LYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPESVPAA 89 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLK 806 + +V L +GNP P I+W + + P+K + + P + +D G Y Sbjct: 90 KESAVKLECFALGNPVPEISWRRTSG--IPFPSKVKMKNSNAVLEIPNFQQEDAGTYECV 147 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 AEN G ++ P ++ + + + + + P PS +W Sbjct: 148 AENRRGKNAARGRLSFH-------AKPHWLQTMADTALSIEANLFWECKANGKPKPSYSW 200 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 +N E ++ I D + + + N+ DSG Y+CVA N G A++ + Sbjct: 201 LKNGEQVAAEGRI--QIDNGALSIAVLNLS---DSGMYQCVAENKHGIIYSSAQLMVLAS 255 Query: 927 KVTFVKH-LQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRXXX 983 F K L+ + G V LEC+ + W + + + ++ G Sbjct: 256 PPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPNG---T 312 Query: 984 XXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIR---KLQDFEVKEKDVAILEVEI 1040 D G CI K+Q + K I E R + + E+ + A+L +I Sbjct: 313 IKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVGESAVLPCQI 372 Query: 1041 NSETA-DV--VWERDGEIIKPKKNKYDFEKRGH--IRKLYIRNTSVHDEGEYSCILR--- 1092 + A DV W +G++I +++ FE+ G L IRN + G+Y C++ Sbjct: 373 AFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDV 432 Query: 1093 DESCTAEVTVVELPP 1107 + T+ + VV+ PP Sbjct: 433 ESLSTSAILVVKGPP 447 Score = 76.2 bits (179), Expect = 9e-12 Identities = 82/331 (24%), Positives = 138/331 (41%), Gaps = 33/331 (9%) Query: 640 PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITN 699 P++ + S + LEC + P P+I+W I + M +VL+I N Sbjct: 83 PESVPAAKESAVKLECFALGNPVPEISWR-------RTSGIPFPSKVKMKNSNAVLEIPN 135 Query: 700 VKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVV 759 ++ GTY VA NR G+ + + + P ++ + + ++ + Sbjct: 136 FQQEDAGTYECVAENRRGKNA----ARGRLSFHAKPHWLQTMADTALSIEANLFWECKAN 191 Query: 760 GNPRPTITWCKNNKPVKAL-PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 G P+P+ +W KN + V A + D SI +L + D G+Y AEN GI +SA Sbjct: 192 GKPKPSYSWLKNGEQVAAEGRIQIDNGALSIAVL---NLSDSGMYQCVAENKHGIIYSSA 248 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEK--GTIKLVARVTRNPVPSITWYRNNEIISPS 876 + V A PP F + +K + + L + P W + NEI+ + Sbjct: 249 QLMV------LASPPNFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRT 302 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 E I +G + I N + D+G Y C+A N G +S ++ I + T + Sbjct: 303 ERINLLPNG---TIKIANATRQ-DAGSYTCIAKNQFGTASTTGKLLI--TEPTRITMRPT 356 Query: 937 SYETEEGKTVILECQTSH----TVSTKWYHN 963 + E G++ +L CQ + VS W N Sbjct: 357 NTEIIVGESAVLPCQIAFDPALDVSFSWAFN 387 Score = 74.1 bits (174), Expect = 4e-11 Identities = 94/442 (21%), Positives = 157/442 (35%), Gaps = 30/442 (6%) Query: 1503 CIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 C G P+P +W ++G+++ + Y+C+A N HG + +S Sbjct: 188 CKANGKPKPSYSWLKNGEQVAAEGRIQIDNGALSIAVLNLSDSGMYQCVAENKHGIIYSS 247 Query: 1563 CVVGIQQKPVITISNEDIKQ--KHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + + P S +K K + G E + E PP +W K L + N Sbjct: 248 AQLMVLASPP-NFSKSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERIN 306 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISR 1680 + I+I R + YT A N GT+S L + + P I Sbjct: 307 LLPN---GTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITMRPTNTEIIVG 363 Query: 1681 ESVT----IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVA-DVDRDVETYCIQKLNENC 1735 ES I + P LD + + D N + +V V D+ IQ L+ Sbjct: 364 ESAVLPCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQ-LSHGG 422 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 +Y+ + E+L + I++ P I + + ++W P NG Sbjct: 423 KYVCLIDTD-----VESLSTSAILVVKG---PPGPPDKVTVEEITDSTAQLSWTPGRDNG 474 Query: 1796 GSPIIDYKVEIKQEGKK-WKXXXXX------XXXXARIQKLSINTTYQFRIYARNEIGTS 1848 SPI Y ++ + W+ A + L+ Y+FR+ ARN +G Sbjct: 475 -SPITGYIIQARTPFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLG 533 Query: 1849 LPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTE-PESNGGSPITNYIIEFKTV 1907 P + K T + P + P + T + + W PE YII F+ + Sbjct: 534 EPSPASAK-TRTEDSIPDTAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPL 592 Query: 1908 KGKSWTKIVTVGGSVHEHCIEN 1929 +WT+ V + N Sbjct: 593 GMVTWTRAAISTPGVARYVFRN 614 Score = 73.7 bits (173), Expect = 5e-11 Identities = 127/567 (22%), Positives = 207/567 (36%), Gaps = 51/567 (8%) Query: 1252 TLIIRKCTEDDQCEYTCVL---------LDAKSTTKLKVEVV--EFPPKI-VDYEREYRI 1299 +L I K D YTCV+ L + + L+ + V E+ PKI V + Sbjct: 29 SLYIAKVERSDVGNYTCVVNNTVTGDKVLSSPTPLVLRSDGVMGEYEPKIEVHFPESVPA 88 Query: 1300 KRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYK 1359 + S V L P P W S I +K + + +A L I + DAG Y+ Sbjct: 89 AKESAVKLECFALGNPVPEISWRRTSGIPFP---SKVKMKNSNAVLEIPNFQQEDAGTYE 145 Query: 1360 LRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 EN G ++ KP L I++ N+ W+ N ++ Sbjct: 146 CVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEA---NLFWECKANGKPKPSYSWLK 202 Query: 1418 EYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +++ I + N SI L + S ++ A N+ I Y + Sbjct: 203 NGEQVAAEGRIQIDN---GALSIAVLNLSDSGMYQCVAENKHGI--------IYSSAQLM 251 Query: 1478 KIQSPT--VEKPLKNIT-TEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYENR 1532 + SP + PLK + ++ L C P P ++ ++ G ++ +T + Sbjct: 252 VLASPPNFSKSPLKALLKARSGSEVTLECKPEAWP-PAISLWKKGNEILPRTERINLLPN 310 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLV 1592 Y CIA N G T+ + I + IT+ + VG+ ++ Sbjct: 311 GTIKIANATRQDAGSYTCIAKNQFGTASTTGKLLITEPTRITM--RPTNTEIIVGESAVL 368 Query: 1593 TAVIEGIPPPEVI--WYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHSSKYTIEA 1647 I P +V W NG ++ ++ N + SV + I+ ++ SH KY Sbjct: 369 PCQIAFDPALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLI 428 Query: 1648 SNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 + S L V P P+ V + EI+ + + W P D+G +T Y I+ Sbjct: 429 DTDVESLSTSAILVVKGPPGPPD-KVTVEEITDSTAQLSWTPGRDNGS-PITGYIIQART 486 Query: 1708 PDNNRWIKVADVDRDVE----TYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 P W V V + T + LN EY FRV+A+N VG E + +T Sbjct: 487 PFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPSPAS-AKTRTE 545 Query: 1764 LDVPSXXXXXXXXXXIDNESVYITWFP 1790 +P + ITW P Sbjct: 546 DSIPDTAPTDVGGGGGTKSELVITWEP 572 Score = 73.7 bits (173), Expect = 5e-11 Identities = 99/461 (21%), Positives = 168/461 (36%), Gaps = 38/461 (8%) Query: 1029 KEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYS 1088 KE V + + + ++ W R I P K K + L I N D G Y Sbjct: 90 KESAVKLECFALGNPVPEISWRRTSGIPFPSKVKM----KNSNAVLEIPNFQQEDAGTYE 145 Query: 1089 CIL---RDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGS 1144 C+ R ++ P + + + ++ +E + K W K+G Sbjct: 146 CVAENRRGKNAARGRLSFHAKPHWLQTMADTALSIEANLFWECKANGKPKPSYSWLKNGE 205 Query: 1145 EIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK----CTAILTVEEPSINFTL 1200 ++ IQ+ L I +L D+G Y C N +A L V NF+ Sbjct: 206 QVAAEGRIQID----NGALSIAVLNLSDSGMYQCVAENKHGIIYSSAQLMVLASPPNFS- 260 Query: 1201 RLPEFILVPANTDAYLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTLIIRK 1257 + P L+ A + + +T+E E W K ++ TE+ L+ + T+ I Sbjct: 261 KSPLKALLKARSGSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPN---GTIKIAN 317 Query: 1258 CTEDDQCEYTCVLLDAKST--TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFP 1315 T D YTC+ + T T K+ + E P +I I G L P Sbjct: 318 ATRQDAGSYTCIAKNQFGTASTTGKLLITE-PTRITMRPTNTEIIVGESAVLPCQIAFDP 376 Query: 1316 --QPNDEWIVNSKII---KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 + W N ++I + H + S S L I+ ++ + G Y ++ + Sbjct: 377 ALDVSFSWAFNGQLIDFQRDGNHFERVGGSVSGDLMIRNIQLSHGGKYVCLIDTDVESLS 436 Query: 1371 VEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISV 1430 + + P PP K + EI S+ + W P S I Y+++ + T W +V Sbjct: 437 TSAILVVKGPPGPPDKVTVEEITDSTAQLSW-TPGRDNGSPITGYIIQARTPFTVGWQAV 495 Query: 1431 KNITKT------QTSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 + + ++ L Y FR A N V + + S Sbjct: 496 DTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEPS 536 Score = 48.0 bits (109), Expect = 0.003 Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 4/80 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS V EC+ E +P W + I+ ++ + + T+ I +DAG++TC Sbjct: 273 GSEVTLECKPEAWPPAISLWKKGNEILPRTERINLLPN----GTIKIANATRQDAGSYTC 328 Query: 584 VAKNAAGFASSTTELIVEAP 603 +AKN G AS+T +L++ P Sbjct: 329 IAKNQFGTASTTGKLLITEP 348 Score = 46.0 bits (104), Expect = 0.011 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 7/109 (6%) Query: 1950 LPTESQSVRLEKHATVPSPPTAP--LEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD 2007 + T+ +S+ V PP P + + + + SW TP D G+P+ GY I R Sbjct: 428 IDTDVESLSTSAILVVKGPPGPPDKVTVEEITDSTAQLSW-TPGRDNGSPITGYIIQART 486 Query: 2008 VTKTMWMEVGKV----DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 W V V + N L + L+ Y R+ ARN +GL EP Sbjct: 487 PFTVGWQAVDTVPEVINGNMLTATVVGLNAWVEYEFRVVARNAVGLGEP 535 Score = 44.0 bits (99), Expect = 0.046 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Query: 525 STVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCV 584 S V+ EC G P P+I+W R + I PS ++ + N A L I EDAGT+ CV Sbjct: 92 SAVKLECFALGNPVPEISWRRTSGIPFPS---KVKMKNSN-AVLEIPNFQQEDAGTYECV 147 Query: 585 AKNAAG 590 A+N G Sbjct: 148 AENRRG 153 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 529 FECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 +EC+ G P+P +W + + Q+ DN A L I + D+G + CVA+N Sbjct: 186 WECKANGKPKPSYSWLKNGEQVAAEGRIQI----DNGA-LSIAVLNLSDSGMYQCVAENK 240 Query: 589 AGFASSTTELIVEA 602 G S+ +L+V A Sbjct: 241 HGIIYSSAQLMVLA 254 >UniRef50_A4JYE0 Cluster: CDNA, clone cssl:d0205; n=2; Danio rerio|Rep: CDNA, clone cssl:d0205 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 744 Score = 95.1 bits (226), Expect = 2e-17 Identities = 80/326 (24%), Positives = 142/326 (43%), Gaps = 26/326 (7%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G ++LLEC +P P I W +G ++ P + + + + L+I NV + G+ Sbjct: 260 GEELLLECIAAGVPTPTITWSKRGGDL-PTKKVRIG------NFDKTLRILNVSEEDIGS 312 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 YT +A NR G + +++K P +E ++++ ES L + G+P+PTI Sbjct: 313 YTCMASNRIGSIRHTVEVQVKAA----PFWLEKPINLVLAPDESGRLVCRANGSPKPTIQ 368 Query: 768 WCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W N +P++ +LP + I + + + VY A N G +A ++V + Sbjct: 369 WLVNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLD-- 426 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGE 886 P + + Q I V E L +P+P + W++N + + Sbjct: 427 ---MAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG 483 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTV 946 +E I +E D G Y CVAS GK + +V ++V++ T + + G TV Sbjct: 484 TLE--IKQAQTE-DQGTYTCVASIILGKMEN--QVRLEVKEPTRIVRAPEHKTEPRGTTV 538 Query: 947 ILECQTSHTVS----TKWYHNKKEIS 968 +C+ H S W ++K +S Sbjct: 539 RFDCRVKHDPSLPATVTWLKDEKPLS 564 Score = 88.6 bits (210), Expect = 2e-15 Identities = 138/594 (23%), Positives = 227/594 (38%), Gaps = 55/594 (9%) Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT K+ Y VD +I++EC P P W G+ N+ M Sbjct: 41 PPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFF----NVGKDPRVTMRSR 96 Query: 692 CSVLKITNVKKFQ--EGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 L+I + K + EG Y A N G A S I+L++ P +V+EP + VR+ Sbjct: 97 SGTLEIRSSGKPEDYEGEYQCFASNNLGTAISNKILLRVSKSPLWPKEVLEP---VTVRE 153 Query: 749 GESVILSAQ-VVGNPRPTITWCKN-NKPV---KALPTKSDGDTHSITILKPKKVKDEGVY 803 G ++L+ G P P W + P+ + + +GD +L K K + Sbjct: 154 GSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVL-AKDAKTDYSC 212 Query: 804 TLKAENSEGIAETSAVITVEEPTEEN--AEPPLFINRFQEITVKE--KGTIKLVARVTRN 859 + E + I + + T++ T N P F++ + K +G L+ + Sbjct: 213 NARFEFTHTIQQKNP-YTLKVQTMRNIPETQPTFLSPTGLSSTKMVLRGEELLLECIAAG 271 Query: 860 -PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P+ITW + + + NFD L I NV SE D G Y C+ASN G H Sbjct: 272 VPTPTITWSKRGGDLPTKKVRIGNFDK---TLRILNV-SEEDIGSYTCMASNRIGSIRHT 327 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM---DHREI 975 V + K + +E ++ S + +W N + I +R + Sbjct: 328 VEVQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRV 387 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFI-RKLQDFEVKE 1030 + + V +C ++ + + V + P + K Q +V E Sbjct: 388 LDD----TIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKNQLIKVIE 443 Query: 1031 KDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 + LE ++ W ++G Y G L I+ D+G Y+C Sbjct: 444 NNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG---TLEIKQAQTEDQGTYTC 500 Query: 1090 ILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL---VRWFKDG 1143 + E V V+ P I+ +++ +G F+ + +L V W KD Sbjct: 501 VASIILGKMENQVRLEVKEPTRIVRAPEHKTEPRGTTVRFDCRVKHDPSLPATVTWLKDE 560 Query: 1144 SEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEE 1193 + FS +L D + L IY+ + DD G Y+C E+ +A LTV E Sbjct: 561 KPLSFSWIGRLKKD--DESLTIYNVNPDDGGTYTCTAKTEIDEDTASARLTVTE 612 Score = 70.5 bits (165), Expect = 5e-10 Identities = 136/602 (22%), Positives = 240/602 (39%), Gaps = 64/602 (10%) Query: 709 TVVAVNREGEASLPIVL--KIKTGEKEPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPT 765 +++++ E A++ + L KI+ K+PP ++ + LK IV +++I+ + GNP PT Sbjct: 14 SIISLLSEEAAAIEVPLDPKIQQELKQPPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPT 73 Query: 766 ITWCKNNK---PVKALPTKSDGDTHSITILKPKKVKD-EGVYTLKAENSEGIAETSAVIT 821 W +N K K + ++ I K +D EG Y A N+ G A ++ ++ Sbjct: 74 FQWRRNGKFFNVGKDPRVTMRSRSGTLEIRSSGKPEDYEGEYQCFASNNLGTAISNKILL 133 Query: 822 VEEPTEENAEPPLFINRFQE-ITVKEKGTIKLVARVTRN-PVPSITWYRNNEIISPSETI 879 ++ PL+ E +TV+E + L P P W + I P Sbjct: 134 ------RVSKSPLWPKEVLEPVTVREGSPLVLACNPPPGLPPPETFWM--DSFIMPIAQD 185 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVA-----SNSAGKSSHGARV----TIDVEKVTF 930 + G N +L +NV ++ DY C A K+ + +V I + TF Sbjct: 186 RRVSMGLNGDLFFSNVLAKDAKTDYSCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTF 245 Query: 931 VK--HLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXX 988 + L + G+ ++LEC + V T K + +++ Sbjct: 246 LSPTGLSSTKMVLRGEELLLEC-IAAGVPTPTITWSKRGGDLPTKKVRIGNFDKTLRILN 304 Query: 989 XXXXDVGVIKCIVKDQETS---TMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN-SET 1044 D+G C+ ++ S T+ V + P ++ K + + + L N S Sbjct: 305 VSEEDIGSYTCMASNRIGSIRHTVEVQVKAAPFWLEKPINLVLAPDESGRLVCRANGSPK 364 Query: 1045 ADVVWERDGEIIK---PKKNKYDFEKRGHIRKLYIRNTSVHD---EGEYSCILRDESCTA 1098 + W +GE I+ P N+ + + +++V+ E+ +L A Sbjct: 365 PTIQWLVNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLL----ANA 420 Query: 1099 EVTVVELPPEII-TRLQNQKVNKGNKATFEIELTKGD-ALVRWFKDGSEIQF-SNHIQLT 1155 V+V+++ P ++ + Q KV + N+ E L+RWFK+G H +L Sbjct: 421 FVSVLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLY 480 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEPSINFTLRLPEFILVPAN 1211 +G L+I +D G Y+C +G + L V+EP+ +R PE P Sbjct: 481 HNG---TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKEPT--RIVRAPEHKTEPRG 535 Query: 1212 TDAYLTVEI---PDETLDVTWYKKKSVIEDTEKFTLISDVKK--RTLIIRKCTEDDQCEY 1266 T + P VTW K + + F+ I +KK +L I DD Y Sbjct: 536 TTVRFDCRVKHDPSLPATVTWLKDEKPL----SFSWIGRLKKDDESLTIYNVNPDDGGTY 591 Query: 1267 TC 1268 TC Sbjct: 592 TC 593 Score = 67.7 bits (158), Expect = 3e-09 Identities = 83/385 (21%), Positives = 144/385 (37%), Gaps = 28/385 (7%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXX 1540 +EKP+ N+ P+E L C G P+P + W +G+ ++++ R Sbjct: 339 LEKPI-NLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLPNPNRRVLDDTIIFETV 397 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y+C A N+HG + + V + + ++ K + + G P Sbjct: 398 QFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSP 457 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 P + W+KNG L + + + IK+ + YT AS G +V L Sbjct: 458 LPLLRWFKNG--LGSGLDGGHYRLYHNGTLEIKQAQTEDQGTYTCVASIILGKMENQVRL 515 Query: 1661 KVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVD 1720 +V + P E +V + + D L T ++ +P + WI + Sbjct: 516 EVKEPTRIVRAPEHKTEPRGTTVRFDCRVK-HDPSLPATVTWLKDEKPLSFSWI--GRLK 572 Query: 1721 RDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 +D E+ I +N + + A+ + E S + + T D S D Sbjct: 573 KDDESLTIYNVNPDDGGTYTCTAKTEI--DEDTASARLTV-TENDSSSASNRSASAGRPD 629 Query: 1781 -----------NESVYITWFPSEKNGGSPIIDYKVEIKQ---EGKKWKXXXXXXXXXARI 1826 SV +TW P +N SP+ + V+ ++ E KW+ + Sbjct: 630 PPQDLELSDPSARSVRLTWVPGNEN-NSPVTHFLVQFEEDRWEPGKWQNLSIYDWNLNSV 688 Query: 1827 Q-KLSINTTYQFRIYARNEIGTSLP 1850 +LS YQFR+ A N +G S P Sbjct: 689 NLQLSPFVNYQFRVIAINAVGQSQP 713 Score = 58.8 bits (136), Expect = 2e-06 Identities = 84/409 (20%), Positives = 152/409 (37%), Gaps = 21/409 (5%) Query: 1278 KLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKP 1336 K++ E+ + PP IV ++Y + ++ + + + P P +W N K K + Sbjct: 33 KIQQELKQ-PPTIVKQSLKDYIVDPRDNIIIECEAKGNPVPTFQWRRNGKFFNVGKDPRV 91 Query: 1337 SIDSKSASLTIKKVENTD--AGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEI-- 1392 ++ S+S +L I+ + G Y+ NN G A + + + SP +LE Sbjct: 92 TMRSRSGTLEIRSSGKPEDYEGEYQCFASNNLGTA-ISNKILLRVSKSPLWPKEVLEPVT 150 Query: 1393 --DSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVK---NITKTQTSIQNLKTNS 1447 + S + + + P + I +S+ ++ + ++ KT+ Sbjct: 151 VREGSPLVLACNPPPGLPPPETFWMDSFIMPIAQDRRVSMGLNGDLFFSNVLAKDAKTDY 210 Query: 1448 SYRFRAYAVNEVDISDA-SETTEYYKVIKETK--IQSPTVEKPLKNITTEPNEDIELTCI 1504 S R + + + + + + I ET+ SPT K + E++ L CI Sbjct: 211 SCNARFEFTHTIQQKNPYTLKVQTMRNIPETQPTFLSPTGLSSTKMVLR--GEELLLECI 268 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC 1563 GVP P +TW + G L T K N Y C+A N G + + Sbjct: 269 AAGVPTPTITWSKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSYTCMASNRIGSIRHTV 328 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 V ++ P + I + + G P P + W NG +E+ N Sbjct: 329 EVQVKAAPFWL--EKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIESSLP-NPNR 385 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + I + ++ S+ Y ASN G + V D + GP Sbjct: 386 RVLDDTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLDMAPRMLGP 434 Score = 51.2 bits (117), Expect = 3e-04 Identities = 56/243 (23%), Positives = 102/243 (41%), Gaps = 27/243 (11%) Query: 1252 TLIIRKCTEDDQCEYTCV--LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL-- 1307 TL I++ +DQ YTCV ++ K ++++EV E P +IV RG+ V Sbjct: 484 TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKE-PTRIVRAPEHKTEPRGTTVRFDC 542 Query: 1308 LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCG 1367 V + W+ + K + + D + SLTI V D G Y + Sbjct: 543 RVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDE--SLTIYNVNPDDGGTYTCTAKTEID 600 Query: 1368 HADVEMNVTILD--------------KPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 +T+ + +P PP + + + S+ + W P N NS + Sbjct: 601 EDTASARLTVTENDSSSASNRSASAGRPDPPQDLELSDPSARSVRLTW-VPGNENNSPVT 659 Query: 1414 YYVVEYQE--IDTTEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 +++V+++E + +W +S+ + ++Q L +Y+FR A+N V S S + Sbjct: 660 HFLVQFEEDRWEPGKWQNLSIYDWNLNSVNLQ-LSPFVNYQFRVIAINAVGQSQPSHPSA 718 Query: 1470 YYK 1472 Y+ Sbjct: 719 RYQ 721 Score = 46.4 bits (105), Expect = 0.009 Identities = 50/208 (24%), Positives = 84/208 (40%), Gaps = 18/208 (8%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +L+ P K + V E + LEC P P + W G + ++ Sbjct: 424 VLDMAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNG--------LGSGLDGG 475 Query: 688 MH--MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + + L+I + +GTYT VA G+ + L++ KEP +++ + Sbjct: 476 HYRLYHNGTLEIKQAQTEDQGTYTCVASIILGKMENQVRLEV----KEPTRIVRAPEHKT 531 Query: 746 VRQGESVILSAQVVGNPR--PTITWCKNNKPVK-ALPTKSDGDTHSITILKPKKVKDEGV 802 +G +V +V +P T+TW K+ KP+ + + D S+TI D G Sbjct: 532 EPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNP-DDGGT 590 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENA 830 YT A+ SA +TV E +A Sbjct: 591 YTCTAKTEIDEDTASARLTVTENDSSSA 618 Score = 45.6 bits (103), Expect = 0.015 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query: 519 KHTPDGSTVQFECQVEGYPR--PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPE 576 K P G+TV+F+C+V+ P +TW + + S ++ DD++ L I V P+ Sbjct: 530 KTEPRGTTVRFDCRVKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDES---LTIYNVNPD 586 Query: 577 DAGTFTCVAKNAAGFASSTTELIV 600 D GT+TC AK +++ L V Sbjct: 587 DGGTYTCTAKTEIDEDTASARLTV 610 Score = 44.0 bits (99), Expect = 0.046 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC G P P ITW ++ + P++ ++ D TL I V ED G++TC Sbjct: 260 GEELLLECIAAGVPTPTITWSKRGGDL-PTKKVRIGNFDK---TLRILNVSEEDIGSYTC 315 Query: 584 VAKNAAGFASSTTELIVEA 602 +A N G T E+ V+A Sbjct: 316 MASNRIGSIRHTVEVQVKA 334 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+E L+ + G+P P + W K G L K+ I +KT +RI + YT Sbjct: 260 GEELLLECIAAGVPTPTITWSKRGGDLPT-KKVRIGNFDKT--LRILNVSEEDIGSYTCM 316 Query: 1647 ASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 ASN G+ V ++V P E P+ Sbjct: 317 ASNRIGSIRHTVEVQVKAAPFWLEKPI 343 Score = 40.7 bits (91), Expect = 0.43 Identities = 94/475 (19%), Positives = 174/475 (36%), Gaps = 41/475 (8%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 + RG ++ L P P W SK K I + +L I V D G Y Sbjct: 257 VLRGEELLLECIAAGVPTPTITW---SKRGGDLPTKKVRIGNFDKTLRILNVSEEDIGSY 313 Query: 1359 KLRLENNCGHADVEMNVTILDKPSPPGKPN--ILEIDSSSINICWDEPENTGNSTIIYYV 1416 N G + V + P KP +L D S +C N I ++ Sbjct: 314 TCMASNRIGSIRHTVEVQVKAAPFWLEKPINLVLAPDESGRLVC---RANGSPKPTIQWL 370 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 V + I+++ + + + ++ SS ++ A NE A+ + V+ Sbjct: 371 VNGEPIESSLPNPNRRVLDDTIIFETVQFESSAVYQCNASNEHGYLLANA---FVSVLD- 426 Query: 1477 TKIQSPTVEKPLKN-ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRX 1533 +P + P I N L C F G P P + W+++G Y + Sbjct: 427 ---MAPRMLGPKNQLIKVIENNRTFLECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHNG 483 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y C+A G++E + +++ I + E + + Sbjct: 484 TLEIKQAQTEDQGTYTCVASIILGKMENQVRLEVKEPTRIVRAPEHKTEPRGTTVRFDCR 543 Query: 1594 AVIEGIPPPEVIWYKNGN--------KLENDKE----YNITTKEK---TSVIRIKELKRS 1638 + P V W K+ +L+ D E YN+ + T + + + + Sbjct: 544 VKHDPSLPATVTWLKDEKPLSFSWIGRLKKDDESLTIYNVNPDDGGTYTCTAKTEIDEDT 603 Query: 1639 HSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLEL 1698 S++ T+ ++++ S+ + D P E + + S SV + W P ++ + Sbjct: 604 ASARLTVTENDSSSASNRSASAGRPDPPQDLE----LSDPSARSVRLTWVPG-NENNSPV 658 Query: 1699 TKYAIEKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 T + ++ E + +W ++ D ++ + +Q L+ Y FRVIA N VG S+ Sbjct: 659 THFLVQFEEDRWEPGKWQNLSIYDWNLNSVNLQ-LSPFVNYQFRVIAINAVGQSQ 712 Score = 39.5 bits (88), Expect = 0.99 Identities = 25/106 (23%), Positives = 54/106 (50%), Gaps = 8/106 (7%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK--SWTKIVTVGGSVH 1923 P P++ +S+ ++RSV L W P + SP+T+++++F+ + + W + +++ Sbjct: 628 PDPPQDLELSDPSARSVRLTWV-PGNENNSPVTHFLVQFEEDRWEPGKWQNLSIYDWNLN 686 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPP 1969 ++ + FR+ A N VG S P+ + ++ T +PP Sbjct: 687 SVNLQ-LSPFVNYQFRVIAINAVGQSQPSHPSA----RYQTSGAPP 727 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 5/75 (6%) Query: 530 ECQVEGYPRPQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 EC G P P + WF+ +++Y++ TL I++ ED GT+TCVA Sbjct: 450 ECPFFGSPLPLLRWFKNGLGSGLDGGHYRLYHN----GTLEIKQAQTEDQGTYTCVASII 505 Query: 589 AGFASSTTELIVEAP 603 G + L V+ P Sbjct: 506 LGKMENQVRLEVKEP 520 Score = 36.3 bits (80), Expect = 9.2 Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 5/157 (3%) Query: 1224 TLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV 1283 T +TW K+ + T+K I + K TL I +E+D YTC+ + + + VEV Sbjct: 274 TPTITWSKRGGDLP-TKKVR-IGNFDK-TLRILNVSEEDIGSYTCMASNRIGSIRHTVEV 330 Query: 1284 -VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 V+ P ++ + L+ P+P +W+VN + I+ P+ Sbjct: 331 QVKAAPFWLEKPINLVLAPDESGRLVCRANGSPKPTIQWLVNGEPIES-SLPNPNRRVLD 389 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 ++ + V+ + +Y+ N G+ V++LD Sbjct: 390 DTIIFETVQFESSAVYQCNASNEHGYLLANAFVSVLD 426 >UniRef50_P20241 Cluster: Neuroglian precursor; n=17; Endopterygota|Rep: Neuroglian precursor - Drosophila melanogaster (Fruit fly) Length = 1302 Score = 95.1 bits (226), Expect = 2e-17 Identities = 158/795 (19%), Positives = 281/795 (35%), Gaps = 35/795 (4%) Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKII 1328 VLLD K + P + R+ RG + L Y P P W + + I Sbjct: 228 VLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRMELFCIYGGTPLPQTVWSKDGQRI 287 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD-VEMNVTILDKPSPPGKP 1387 + KS L I++ DAG Y + N G+A + + + P +P Sbjct: 288 QWSDRITQGHYGKS--LVIRQTNFDDAGTYTCDVSNGVGNAQSFSIILNVNSVPYFTKEP 345 Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 I + ++ I ++ + I+ + + +T I NL Sbjct: 346 EIATAAEDE-EVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDNTIRIINLVKGD 404 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 + + A N + Y V + + PT+ + ++T ++ + C G Sbjct: 405 TGNYGCNATNSLGYV-------YKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKCRVNG 457 Query: 1508 VPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGI 1567 P+P V W R L + + Y C A N GE++ + + Sbjct: 458 SPKPLVKWLRASNWLTGGRYNVQANGDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVV 517 Query: 1568 QQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKT 1627 ++ IT ++ + + + E+ W+K+G ++ + + Sbjct: 518 KEHTRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDN 577 Query: 1628 SVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEW 1687 S+ K ++ S +YT A ++ L V D P+ P+ I + + I W Sbjct: 578 SLTIAKTMELD-SGEYTCVARTRLDEATARANLIVQDVPNAPKLTGITCQADKAE--IHW 634 Query: 1688 KPPLDDGGLELTKYAIEKHEPDNNR-WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNP 1746 + D+ + Y I+ + W + + ++ + +++ Y FRVIA N Sbjct: 635 EQQGDNRS-PILHYTIQFNTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNK 693 Query: 1747 VGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP-SEKNGGSPIIDYKVE 1805 +G S + T DVP + ++ I+W P E +P Y V Sbjct: 694 IGASPP-SAHSDSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNFHYYVS 752 Query: 1806 IKQE--GKKWKXXXXXXXXXARIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGK 1861 K++ W+ I T Y ++ A N+ G S +++ + Sbjct: 753 WKRDIPAAAWENNNIFDWRQNNIVIADQPTFVKYLIKVVAINDRGES-NVAAEEVVGYSG 811 Query: 1862 TLTPPSQPRNFVVSEST-SRSVTLKWTE-PESNGGSPITNYIIEFKTV-KGKSWTKIVTV 1918 P P NF + + T S S + WT E + Y I+ T +G+ + + V Sbjct: 812 EDRPLDAPTNFTMRQITSSTSGYMAWTPVSEESVRGHFKGYKIQTWTENEGEEGLREIHV 871 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMV 1978 G H + K + RI A N G S + + VPS P L+ + Sbjct: 872 KGDTHNALVTQFKPDSKNYARILAYN--GRFNGPPSAVIDFDTPEGVPS-PVQGLDAYPL 928 Query: 1979 GSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGK-----VDVNTLKFNIRDLSE 2033 GS+ M W P + G L GY I +V ++ E + D + + L Sbjct: 929 GSSAFMLHWKKPLYPNG-KLTGYKIYYEEVKESYVGERREYDPHITDPRVTRMKMAGLKP 987 Query: 2034 NHTYMIRIYARNEIG 2048 N Y I I A ++G Sbjct: 988 NSKYRISITATTKMG 1002 Score = 93.5 bits (222), Expect = 6e-17 Identities = 129/589 (21%), Positives = 224/589 (38%), Gaps = 51/589 (8%) Query: 530 ECQVEGYPRPQITWFRQTAIIK-PSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNA 588 EC+ +G P P+ +W + + D +M TLVI ED G + C A N Sbjct: 58 ECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQPGR-GTLVITIPKDEDRGHYQCFASNE 116 Query: 589 AGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX-XXXXADILEGIPPTFSKKPKAQYVDE 647 G A+S + + +A L+ E +G P + +D Sbjct: 117 FGTATSNSVYVRKAELNAFKDEAAKTLEAVEGEPFMLKCAAPDGFPSPTVNWMIQESIDG 176 Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 + R+ PE ++ W V E+ S SD + CS + +++ G Sbjct: 177 SIKSINNSRMTLDPEGNL-WFSN----VTREDAS----SDFYYACSATSVFR-SEYKIGN 226 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPP--QVIEPLKSMIVRQGESVILSAQVVGNPRPT 765 ++ V + G ++ + K PP Q + +S+ +R G+ + L G P P Sbjct: 227 KVLLDVKQMGVSA--------SQNKHPPVRQYVSRRQSLALR-GKRMELFCIYGGTPLPQ 277 Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 W K+ + ++ + G +++ D G YT N G A++ ++I Sbjct: 278 TVWSKDGQRIQWSDRITQGHYGKSLVIRQTNFDDAGTYTCDVSNGVGNAQSFSII----- 332 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 N+ P F + T E + R P P I+W N + I S + Sbjct: 333 LNVNS-VPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVT 391 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 +N +I V D+G+Y C A+NS G + + E T + + T +G+ Sbjct: 392 DNTIRIINLVKG--DTGNYGCNATNSLGYVYKDVYLNVQAEPPT-ISEAPAAVSTVDGRN 448 Query: 946 VILECQTSHTVS--TKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 V ++C+ + + KW ++G R +Q D G C ++ Sbjct: 449 VTIKCRVNGSPKPLVKWLRASNWLTG--GRYNVQAN--GDLEIQDVTFSDAGKYTCYAQN 504 Query: 1004 Q----ETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEV-EINSETADVV--WERDGEII 1056 + + LVVKE ++ Q++EV A E + +T ++ W +DG+ I Sbjct: 505 KFGEIQADGSLVVKEH-TRITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDWWKDGQSI 563 Query: 1057 KPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD--ESCTAEVTVV 1103 + F K L I T D GEY+C+ R + TA ++ Sbjct: 564 DFEAQP-RFVKTND-NSLTIAKTMELDSGEYTCVARTRLDEATARANLI 610 Score = 86.6 bits (205), Expect = 7e-15 Identities = 70/297 (23%), Positives = 126/297 (42%), Gaps = 23/297 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F+K+P+ E +++ ECR +PEP I+W+ G+ I +D + Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTD-----N 393 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 ++I N+ K G Y A N G + L + + EPP + E ++ G +V Sbjct: 394 TIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNV---QAEPPTISEAPAAVSTVDGRNVT 450 Query: 754 LSAQVVGNPRPTITWCKNNKPVKA--LPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 + +V G+P+P + W + + + +++GD ++ D G YT A+N Sbjct: 451 IKCRVNGSPKPLVKWLRASNWLTGGRYNVQANGDLE----IQDVTFSDAGKYTCYAQNKF 506 Query: 812 GIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 G + + V+E T EP + E+ + T + I W+++ + Sbjct: 507 GEIQADGSLVVKEHTRITQEPQNY-----EVAAGQSATFRCNEAHDDTLEIEIDWWKDGQ 561 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKV 928 I E + + L I E+DSG+Y CVA +++ AR + V+ V Sbjct: 562 SID-FEAQPRFVKTNDNSLTIAKT-MELDSGEYTCVARTRLDEAT--ARANLIVQDV 614 Score = 50.0 bits (114), Expect = 7e-04 Identities = 128/605 (21%), Positives = 221/605 (36%), Gaps = 59/605 (9%) Query: 729 TGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV--KALPTKS--DG 784 T + P +++ + I+ + G P P +W KN K +A + Sbjct: 32 TKQPAPGELLFKVAQQNKESDNPFIIECEADGQPEPEYSWIKNGKKFDWQAYDNRMLRQP 91 Query: 785 DTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV 844 ++ I PK +D G Y A N G A +++V E NA + + Sbjct: 92 GRGTLVITIPKD-EDRGHYQCFASNEFGTATSNSVYV--RKAELNAFKDEAAKTLEAVE- 147 Query: 845 KEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN---FDGENIELVITNVDSEIDS 901 E +K A P P++ W I ++I + D E L +NV E S Sbjct: 148 GEPFMLKCAAP-DGFPSPTVNWMIQESIDGSIKSINNSRMTLDPEG-NLWFSNVTREDAS 205 Query: 902 GD-YKCVASNSAGKSSH--GARVTIDVEKVTFV----KHLQ-KSYETEE------GKTVI 947 D Y ++ S +S + G +V +DV+++ KH + Y + GK + Sbjct: 206 SDFYYACSATSVFRSEYKIGNKVLLDVKQMGVSASQNKHPPVRQYVSRRQSLALRGKRME 265 Query: 948 LECQTSHTV--STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD-- 1003 L C T T W + + I D I Q D G C V + Sbjct: 266 LFCIYGGTPLPQTVWSKDGQRIQWSDR--ITQGHYGKSLVIRQTNFDDAGTYTCDVSNGV 323 Query: 1004 --QETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINS-ETADVVWERDGEIIKPKK 1060 ++ ++++ ++P F ++ + E + + E + W +G+ I+ + Sbjct: 324 GNAQSFSIILNVNSVPYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIE--Q 381 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESC----TAEVTVVELPPEIITRLQNQ 1116 + + + + I N D G Y C + + V PP I Sbjct: 382 STPNPRRTVTDNTIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAV 441 Query: 1117 KVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 G T + + LV+W + + + + + +G L+I D DAG+ Sbjct: 442 STVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGRY-NVQANGD---LEIQDVTFSDAGK 497 Query: 1176 YSC----EVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVT--W 1229 Y+C + G + L V+E + T + + + + E D+TL++ W Sbjct: 498 YTCYAQNKFGEIQADGSLVVKEHT-RITQEPQNYEVAAGQSATFRCNEAHDDTLEIEIDW 556 Query: 1230 YKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV----LLDAKSTTKLKVEVVE 1285 +K I D E +L I K E D EYTCV L +A + L V+ V Sbjct: 557 WKDGQSI-DFEAQPRFVKTNDNSLTIAKTMELDSGEYTCVARTRLDEATARANLIVQDVP 615 Query: 1286 FPPKI 1290 PK+ Sbjct: 616 NAPKL 620 Score = 49.6 bits (113), Expect = 0.001 Identities = 57/263 (21%), Positives = 104/263 (39%), Gaps = 19/263 (7%) Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE----VGNSKCTAILTVEEP 1194 W KDG IQ+S+ I GK L I + DDAG Y+C+ VGN++ +I+ + Sbjct: 280 WSKDGQRIQWSDRITQGHYGKS--LVIRQTNFDDAGTYTCDVSNGVGNAQSFSII-LNVN 336 Query: 1195 SINFTLRLPEFILVPANTDAYL---TVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKR 1251 S+ + + PE + + +P+ ++W IE + V Sbjct: 337 SVPYFTKEPEIATAAEDEEVVFECRAAGVPEP--KISWIHNGKPIEQSTP-NPRRTVTDN 393 Query: 1252 TLIIRKCTEDDQCEYTCVLLDAKSTT--KLKVEVVEFPPKIVDYEREYRIKRGSDVTLLV 1309 T+ I + D Y C ++ + + V PP I + G +VT+ Sbjct: 394 TIRIINLVKGDTGNYGCNATNSLGYVYKDVYLNVQAEPPTISEAPAAVSTVDGRNVTIKC 453 Query: 1310 DYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA 1369 P+P +W+ S + ++ + + L I+ V +DAG Y +N G Sbjct: 454 RVNGSPKPLVKWLRASNWLTGGRYNVQA----NGDLEIQDVTFSDAGKYTCYAQNKFGEI 509 Query: 1370 DVEMNVTILDKPSPPGKPNILEI 1392 + ++ + + +P E+ Sbjct: 510 QADGSLVVKEHTRITQEPQNYEV 532 Score = 47.6 bits (108), Expect = 0.004 Identities = 52/198 (26%), Positives = 84/198 (42%), Gaps = 21/198 (10%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PPT S+ P A +G ++ ++CR+ P+P + WL + + +V D Sbjct: 431 PPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWL-RASNWLTGGRYNVQANGD----- 484 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L+I +V G YT A N+ GE A +V+K T + PQ E V G+ Sbjct: 485 --LEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVKEHTRITQEPQNYE------VAAGQ 536 Query: 751 SVILSAQVVGNP--RPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLK 806 S + I W K+ + + +A P + +S+TI K ++ D G YT Sbjct: 537 SATFRCNEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLTIAKTMEL-DSGEYTCV 595 Query: 807 AENSEGIAETSAVITVEE 824 A A A + V++ Sbjct: 596 ARTRLDEATARANLIVQD 613 Score = 46.0 bits (104), Expect = 0.011 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 5/96 (5%) Query: 506 QSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV 565 Q+ P E T DG V +C+V G P+P + W R + + + Y+ Sbjct: 428 QAEPPTISEAPAAVSTVDGRNVTIKCRVNGSPKPLVKWLRASNWLTGGR-----YNVQAN 482 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 L I++V DAG +TC A+N G + L+V+ Sbjct: 483 GDLEIQDVTFSDAGKYTCYAQNKFGEIQADGSLVVK 518 Score = 41.5 bits (93), Expect = 0.25 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 2/93 (2%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F ++ + V FEC+ G P P+I+W I+ S DN T+ Sbjct: 339 PYFTKEPEIATAAEDEEVVFECRAAGVPEPKISWIHNGKPIEQSTPNPRRTVTDN--TIR 396 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEA 602 I + D G + C A N+ G+ L V+A Sbjct: 397 IINLVKGDTGNYGCNATNSLGYVYKDVYLNVQA 429 Score = 37.9 bits (84), Expect = 3.0 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF-QMYYDDDNVATLVIREVFPEDAGTFT 582 G ++ C G P PQ W + I+ S Q +Y +LVIR+ +DAGT+T Sbjct: 261 GKRMELFCIYGGTPLPQTVWSKDGQRIQWSDRITQGHYGK----SLVIRQTNFDDAGTYT 316 Query: 583 CVAKNAAGFASS 594 C N G A S Sbjct: 317 CDVSNGVGNAQS 328 >UniRef50_Q4KMQ7 Cluster: NRCAM protein; n=10; Euteleostomi|Rep: NRCAM protein - Homo sapiens (Human) Length = 771 Score = 94.7 bits (225), Expect = 2e-17 Identities = 114/478 (23%), Positives = 194/478 (40%), Gaps = 48/478 (10%) Query: 507 SMAPIFV-EKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKP-SQDFQMYYDDD 563 S +P++ EKL P G ++ C+ G P P I W + P S+ + D Sbjct: 136 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD 195 Query: 564 NVATLVIREVFPEDAGT-FTCVAK-NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 L V PED + C A+ N + V+ D ++ T+ Sbjct: 196 ----LYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND-TIAANLSDTE 250 Query: 622 XXXXADILEGIPPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 E PPTF + + A +E G+ + LEC +P P I W K + ++P + Sbjct: 251 FYGAKSSRER-PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA-KEDGMLP-K 307 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 N +V + L+I +V + G Y +A N G I +++K P I Sbjct: 308 NRTVYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA----PYWI 358 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKP 794 +++++ GE L + GNP+P I+W N P++ P K DGDT I Sbjct: 359 TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT---IIFSN 415 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLV 853 + + VY A N G +A + V AEPP + + V L Sbjct: 416 VQERSSAVYQCNASNEYGYLLANAFVNV------LAEPPRILTPANTLYQVIANRPALLD 469 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +P+P+I W++ + + E I + +E+ + DS +G Y CVA N G Sbjct: 470 CAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDS---TGTYTCVARNKLG 526 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH----TVSTKWYHNKKEI 967 + + V ++++ T++ + + G V EC+ H +++ W + +E+ Sbjct: 527 MAKN--EVHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 582 Score = 81.8 bits (193), Expect = 2e-13 Identities = 132/623 (21%), Positives = 249/623 (39%), Gaps = 71/623 (11%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT +++ PK +D +I+++C P P +W G D++ V ++ Sbjct: 39 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 98 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + + EG Y A N G A S IV++ + P E L+ + ++ G+ Sbjct: 99 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKEKLEPITLQSGQ 155 Query: 751 SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803 S++L + +G P P I W N+ + LP +GD + +L P+ +++ + Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 212 Query: 804 TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843 + +++ I + + VI+V+E TE PP F+ + Sbjct: 213 YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNAS 272 Query: 844 VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 KE +G + + + P P I W + + ++ + T+ +NF+ + ++++ SE D Sbjct: 273 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-KTLQIIHV---SEAD 328 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960 SG+Y+C+A N+ G H V + E T+I + W Sbjct: 329 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388 Query: 961 YHN--KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014 N EI+ D I +G V +C ++ + + V Sbjct: 389 LTNGVPIEIAPDDPSRKI-DGDTIIFSNVQERSS--AVYQCNASNEYGYLLANAFVNVLA 445 Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 P + ++V A+L+ S + W + + ++ Y + G Sbjct: 446 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--- 502 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPE--IITRLQNQKVNKGNKATFEIE 1129 L I G Y+C+ R++ A+ V +E+ I+ + + V +G+ +FE + Sbjct: 503 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECK 562 Query: 1130 LTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--- 1183 + L V W KD E+ + T+D K L + D DD+G Y+C + Sbjct: 563 VKHDHTLSLTVLWLKDNRELPSDE--RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDS 618 Query: 1184 -KCTAILT-VEEPSINFTLRLPE 1204 +A+L+ V+ P+ F L L + Sbjct: 619 VSASAVLSVVDVPNPPFDLELTD 641 Score = 79.4 bits (187), Expect = 1e-12 Identities = 95/423 (22%), Positives = 171/423 (40%), Gaps = 41/423 (9%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXX 1545 +N+ P ED L C G P+P+++W +G ++ A + Sbjct: 362 QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSS 421 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C A N++G + + V + +P ++ + + L+ G P P + Sbjct: 422 AVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIE 481 Query: 1606 WYK--NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 W+K G+ L D I + + I ++ + YT A N G + EV L++ Sbjct: 482 WFKGAKGSALHED----IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 537 Query: 1664 DKP---SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVAD 1718 D +PE V+ R V+ E K D L LT ++ + P + R+ Sbjct: 538 DATWIVKQPEYAVVQR---GSMVSFECKVK-HDHTLSLTVLWLKDNRELPSDERF----T 589 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXX 1778 VD+D + ++++ + +A + +++ + ++ + +DVP+ Sbjct: 590 VDKD--HLVVADVSDDDSGTYTCVANTTL---DSVSASAVL--SVVDVPNPPFDLELTDQ 642 Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARIQ-KLSINTT 1834 +D +SV ++W P + N SPI + +E + K W Q KLS Sbjct: 643 LD-KSVQLSWTPGDDN-NSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVN 700 Query: 1835 YQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----E 1890 Y FR+ A N IG SLP + ++ + K P P S ++ + W +P E Sbjct: 701 YSFRVMAVNSIGKSLPSEASEQY-LTKASEPDKNPTAVEGLGSEPDNLVITW-KPLNGFE 758 Query: 1891 SNG 1893 SNG Sbjct: 759 SNG 761 Score = 71.3 bits (167), Expect = 3e-10 Identities = 108/467 (23%), Positives = 183/467 (39%), Gaps = 41/467 (8%) Query: 1044 TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 T + W ++ ++ + Y +FEK L I + S D G Y CI ++ T+ Sbjct: 293 TPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNALGAIHHTI 347 Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFS-NHIQLTI 1156 V+ P IT QN ++ G T I G+ R W +G I+ + + I Sbjct: 348 SVRVKAAPYWITAPQNLVLSPGEDGTL-ICRANGNPKPRISWLTNGVPIEIAPDDPSRKI 406 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 DG + + + Y C N + +N L P IL PANT Y Sbjct: 407 DG--DTIIFSNVQERSSAVYQCNASNEYGYLLANA---FVN-VLAEPPRILTPANT-LYQ 459 Query: 1217 TVEIPDETLDVTWYKKK-SVIE---DTEKFTLISDV----KKRTLIIRKCTEDDQCEYTC 1268 + LD ++ IE + L D+ + TL I +D YTC Sbjct: 460 VIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 519 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 V + K +V + + + EY + +RGS +V ++ + +D + + + Sbjct: 520 VARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGS----MVSFECKVK-HDHTLSLTVL 574 Query: 1328 IKKCKHTKPSIDSKSAS---LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPP 1384 K PS + + L + V + D+G Y ++++D P+PP Sbjct: 575 WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPP 634 Query: 1385 GKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQ- 1441 + + S+ + W P + NS I +++EY++ W ++ TQT+ Q Sbjct: 635 FDLELTDQLDKSVQLSW-TPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL 693 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPL 1488 L +Y FR AVN + S SE +E Y ++PT + L Sbjct: 694 KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGL 740 Score = 57.6 bits (133), Expect = 4e-06 Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 12/290 (4%) Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 PP P I +D+S + E + G + +Y+ E ++I TQT IQ Sbjct: 168 PP--PIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQ 224 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDI 1499 + S +N+ ++ S+T E+Y K ++ + PT P N + + + Sbjct: 225 KQPISVKVISVDELNDTIAANLSDT-EFYGA-KSSRERPPTFLTPEGNASNKEELRGNVL 282 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 L CI G+P P + W ++ L + Y+N Y+CIA N G Sbjct: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 342 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + + V ++ P + +++ G++ + G P P + W NG +E + Sbjct: 343 IHHTISVRVKAAPYWITAPQNLVL--SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 400 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + + K I ++ S+ Y ASN G + V +P + Sbjct: 401 -DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPR 449 Score = 54.0 bits (124), Expect = 4e-05 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 4/122 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923 P+ P + +++ +SV L WT P + SPIT +IIE++ K W V G+ Sbjct: 631 PNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 689 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 ++ + FR+ A N++G SLP+E+ L K + PTA + N+V Sbjct: 690 TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 748 Query: 1984 MT 1985 +T Sbjct: 749 IT 750 Score = 40.7 bits (91), Expect = 0.43 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 8/92 (8%) Query: 524 GSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 GS V FEC+V+ +T W + + + F + D D+ LV+ +V +D+GT+ Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDH---LVVADVSDDDSGTY 608 Query: 582 TCVAKNAAGFASSTTEL-IVEAPLSDHGSEMT 612 TCVA S++ L +V+ P E+T Sbjct: 609 TCVANTTLDSVSASAVLSVVDVPNPPFDLELT 640 >UniRef50_Q9NR99 Cluster: Matrix-remodeling-associated protein 5 precursor; n=12; Amniota|Rep: Matrix-remodeling-associated protein 5 precursor - Homo sapiens (Human) Length = 2828 Score = 94.7 bits (225), Expect = 2e-17 Identities = 179/935 (19%), Positives = 341/935 (36%), Gaps = 72/935 (7%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P +K P+ V +D + C P+P + W + N I+ + Sbjct: 1853 PQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPN--TRIQRFEVLKN 1910 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L I V+ G Y A N G + ++L + ++P + + + V G+++ Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTV--QQPQILASHYQDVTVYLGDTI 1968 Query: 753 ILSAQVVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPKKV--KDEGVYTLKAE 808 + G P P I+W ++ V P +S H L K+ D GVY A Sbjct: 1969 AMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVAS 2028 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 N+ G + + V P + + + I++ +I + P+PS+ W Sbjct: 2029 NAAGADSLAIRLHVAA-----LPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVL 2083 Query: 869 NNEI-ISPSETITQN-FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID-- 924 + I PS+ + N F N L I N+ + DSG Y+CVA+N G + ++ + Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPK-DSGRYECVAANLVGSARRTVQLNVQRA 2142 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--W-YHNKKEISGM-DHREIIQEGR 980 + + G T+ L+C S + W +K+ I + I+ Sbjct: 2143 AANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFA 2202 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEK------DVA 1034 D G C+ +++ +V+K + K++ E + D+ Sbjct: 2203 NGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLK 2262 Query: 1035 ILEVEINSETADVVWE-RDGEIIKPKKNKYDFEKRG------HIRKLYIRNTSVHDEGEY 1087 + V ++ W DG ++ D R + LY + +EG+Y Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDY 2322 Query: 1088 SCILRD----ESCTAEVTVVELPPEIITRLQ-NQKVNKGNKATFEIELTKGDAL--VRWF 1140 +C + + V VV P I + +V G+ T E KG+ + V W Sbjct: 2323 TCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACE-AKGEPMPKVTWL 2381 Query: 1141 KDGSEI--QFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAI-LTVE 1192 +++ S Q+ DG L I D+G Y+C V NS K I + V+ Sbjct: 2382 SPTNKVIPTSSEKYQIYQDG---TLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQ 2438 Query: 1193 EPSINFTLRLPEFILVPANTDAYLTVEIPDE---TLDVTWYKKKSVIEDTEKF-TLISDV 1248 P IN + A + ++ E T V W + V+ + I+ Sbjct: 2439 PPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVH 2498 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPP--KIVDYE---REYRIKRGS 1303 +L IR + D + C+ + +L +++ P K + ++ + G Sbjct: 2499 GNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKPIFHDPISEKITAMAGH 2558 Query: 1304 DVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRL 1362 ++L P P+ W++ N ++ + + L I + + DAG Y+ Sbjct: 2559 TISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVA 2618 Query: 1363 ENNCGHADVEMNVTILDKPSPPGK-PNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 N GH + +++ + KP + N++ I + P G + + Sbjct: 2619 RNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLPNGMH 2678 Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVN-EVDISDASETTEYYKVIKETKIQ 1480 ++ + ++ ++ ++ S + Y E + + + + +I Sbjct: 2679 LEGPQ--TLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRIT 2736 Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW 1515 S +P I T P ++L C+ G+P+ +TW Sbjct: 2737 S----EPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767 Score = 74.9 bits (176), Expect = 2e-11 Identities = 171/830 (20%), Positives = 297/830 (35%), Gaps = 85/830 (10%) Query: 599 IVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTF-SKKPKAQYVDEGSDILLECRL 657 I EA SD G V + +PP +K + + G I + C Sbjct: 2012 IKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTA 2071 Query: 658 VAIPEPDIAWLF-KGEEIVPDENISVAIESDMHMYCS-VLKITNVKKFQEGTYTVVAVNR 715 A P P + W+ G +I P + + ++ ++ + L I N+ G Y VA N Sbjct: 2072 KAAPLPSVRWVLGDGTQIRPSQ----FLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANL 2127 Query: 716 EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITW-CKNNKP 774 G A + L ++ + VR G ++ L G+P P I W + + Sbjct: 2128 VGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRM 2187 Query: 775 VKAL---PTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + AL ++ + ++K KD G Y A N G + V+ V+ + Sbjct: 2188 IDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVG--DDYVVLKVDVVMK---- 2241 Query: 832 PPLFINRFQEITVKE--KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 P I +E K G +K+ T P P I+W + + S + + G Sbjct: 2242 -PAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKR 2300 Query: 890 LVITNVDS----EI---DSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEE 942 V+ N + E+ + GDY C A N GK RV + T + + Sbjct: 2301 YVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPY 2360 Query: 943 GKTVILECQTSHTVSTK--WYH--NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIK 998 G V + C+ K W NK + + +I Q+G D G Sbjct: 2361 GDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDG---TLLIQKAQRSDSGNYT 2417 Query: 999 CIVKD---QETSTMLVVKETIPEFIRKLQDFEVKEKDVA------ILEVEINS-ETADVV 1048 C+V++ ++ T+ + P I + +++A +++ + T V+ Sbjct: 2418 CLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVL 2477 Query: 1049 WERDGEIIKPKK---NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA----EVT 1101 W ++ P N+ G L IR+ D + C+ R+E A ++T Sbjct: 2478 WAFPEGVVLPAPYYGNRITVHGNG---SLDIRSLRKSDSVQLVCMARNEGGEARLILQLT 2534 Query: 1102 VVE-LPPEIITRLQNQKVNKGNKATFEIEL----TKGDALVRWFKDGSEIQFSNHIQLTI 1156 V+E + I ++K+ T + T +LV +G+++Q +Q Sbjct: 2535 VLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFY 2594 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNS-----KCTAILTVEEPSINFTLRLPEFILVPAN 1211 L I DAG Y C N+ + ++ +P N + + + Sbjct: 2595 HKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEAN--KQYHNLVSIING 2652 Query: 1212 TDAYLTVEIPDETLD-VTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 L P +W + +E + +S + TL +R+ + D+ Y C Sbjct: 2653 ETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCR 2712 Query: 1270 LLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKR-GSDVTLLVDYQAFPQPNDEWIVNSK 1326 + S T + V V+ +PP+I R G+ V L P+ + W + K Sbjct: 2713 METEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDK 2772 Query: 1327 IIKKCKHTKPSIDSK---------SASLTIKKVENTDAGIYKLRLENNCG 1367 H K + ++ SLTI+ DAG YK +N G Sbjct: 2773 -----SHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILG 2817 Score = 74.5 bits (175), Expect = 3e-11 Identities = 154/761 (20%), Positives = 275/761 (36%), Gaps = 84/761 (11%) Query: 511 IFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI-IKPSQDFQMYYDDDNVATLV 569 I EKL P G ++ C + P P + W I+PSQ TL Sbjct: 2049 IHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLY 2108 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADIL 629 IR + P+D+G + CVA N G A T +L V+ ++ Sbjct: 2109 IRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAAN----------------------- 2145 Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 I T ++ +Y G + L+C P P I W + ++ + + +S + Sbjct: 2146 ARITGTSPRRTDVRY---GGTLKLDCSASGDPWPRILWRLPSKRMI---DALFSFDSRIK 2199 Query: 690 MYCS-VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 ++ + L + +V G Y VA N+ G+ +VLK+ K + V Sbjct: 2200 VFANGTLVVKSVTDKDAGDYLCVARNKVGDDY--VVLKVDVVMKPAKIEHKEENDHKVFY 2257 Query: 749 GESVILSAQVVGNPRPTITW-CKNNKPVKALPTKSD--GDTHSITI-------LKPKKVK 798 G + + G P P I+W + V + D G T + ++ Sbjct: 2258 GGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMR 2317 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 +EG YT AEN G E + V A + + + V + + Sbjct: 2318 EEGDYTCFAENQVGKDEMRVRVKV-----VTAPATIRNKTYLAVQVPYGDVVTVACEAKG 2372 Query: 859 NPVPSITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 P+P +TW N++I S Q + ++ L+I DSG+Y C+ NSAG+ Sbjct: 2373 EPMPKVTWLSPTNKVIPTSSEKYQIY--QDGTLLIQKAQRS-DSGNYTCLVRNSAGEDRK 2429 Query: 918 GARVTIDVEKVTFVKHLQKSYETEE----GKTVILECQTS--HTVSTKWYHNKKEISGMD 971 + ++V+ + E G +++C+ T W + + Sbjct: 2430 TVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAP 2489 Query: 972 H--REIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRK-LQDFEV 1028 + I G V ++ C+ +++ L+++ T+ E + K + + Sbjct: 2490 YYGNRITVHGNGSLDIRSLRKSDSVQLV-CMARNEGGEARLILQLTVLEPMEKPIFHDPI 2548 Query: 1029 KEKDVAIL--EVEIN-----SETADVVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTS 1080 EK A+ + +N + T +VW +G ++ + F + L+I S Sbjct: 2549 SEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKAD-GMLHISGLS 2607 Query: 1081 VHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELT---KGD 1134 D G Y C+ R+ + E V V L PE + N V+ N T ++ T G Sbjct: 2608 SVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHN-LVSIINGETLKLPCTPPGAGQ 2666 Query: 1135 ALVRW-FKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE 1193 W +G ++ + L + + + D G Y C + ++ ++ Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726 Query: 1194 PSINFTLRL-----PEFILVPANTDAYLTVEIPDETLDVTW 1229 I + R+ P P NT + + D+TW Sbjct: 2727 IVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767 Score = 73.7 bits (173), Expect = 5e-11 Identities = 136/660 (20%), Positives = 247/660 (37%), Gaps = 46/660 (6%) Query: 1072 RKLYIRNTSVHDEGEYSCILRD----ESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATF 1126 R L I+ S D G Y C+ + +S + V LPP I +L+N + G + Sbjct: 2008 RTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPG--LSI 2065 Query: 1127 EIELTKGDA---LVRW-FKDGSEIQFSNHIQLTIDG-KKQKLKIYDCDLDDAGEYSCE-- 1179 I T A VRW DG++I+ S + + L I + D+G Y C Sbjct: 2066 HIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAA 2125 Query: 1180 --VGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP---DETLDVTW-YKKK 1233 VG+++ T L V+ + N + L ++ D + W K Sbjct: 2126 NLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSK 2185 Query: 1234 SVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKI 1290 +I+ F + I TL+++ T+ D +Y CV + LKV+VV P KI Sbjct: 2186 RMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKI 2245 Query: 1291 VDYER-EYRIKRGSDVTLLVDYQAFPQPNDEW------IVNSKIIKKCK--HTKPSIDSK 1341 E ++++ G D+ + P P W +VNS + TK + Sbjct: 2246 EHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFN 2305 Query: 1342 SASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICW 1401 + +L +V + G Y EN G ++ + V ++ P+ L + ++ Sbjct: 2306 NGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVT 2365 Query: 1402 DEPENTGNSTI-IYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVD 1460 E G + ++ ++ T + IQ + + S + N Sbjct: 2366 VACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSA- 2424 Query: 1461 ISDASETTEYYKVIKETKIQ-SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW-YRD 1518 + +T + ++ KI +P ++ I + + + C G+P P+V W + + Sbjct: 2425 -GEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKL-IDCKAEGIPTPRVLWAFPE 2482 Query: 1519 GKKLKTA----KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 G L + T C+A N+ GE + + + Sbjct: 2483 GVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLEPMEKP 2542 Query: 1575 ISNEDIKQK--HKVGDEWLVTAVIEGIPPPEVIWY-KNGNKLENDKEYNITTKEKTSVIR 1631 I ++ I +K G + G P P ++W NG L++ ++ + ++ Sbjct: 2543 IFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLH 2602 Query: 1632 IKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKP-SKPEGPVIMREISRESVTIEWKPP 1690 I L + Y A N AG + V+LKV KP + + ++ I+ E++ + PP Sbjct: 2603 ISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPP 2662 Score = 69.7 bits (163), Expect = 8e-10 Identities = 99/504 (19%), Positives = 186/504 (36%), Gaps = 36/504 (7%) Query: 1192 EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD-VTWYKKKS--VIEDTEKFTLISDV 1248 E+P I + P+ + V A TD E + VTW K + ++ + + Sbjct: 1851 EKPQI--LTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVL 1908 Query: 1249 KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKV---EVVEFPPKIVDYEREYRIKRGSDV 1305 K TL+IRK D+ +Y C + ++ V V+ P + + ++ + G + Sbjct: 1909 KNGTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTI 1968 Query: 1306 TLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSID-SKSASLTIKKVENTDAGIYKLRLE 1363 + + P P WI + ++ + + I ++ +L+IK+ +D G+YK Sbjct: 1969 AMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVAS 2028 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEID---SSSINI-CWDEPENTGNSTIIYYVVEY 1419 N G + + + + P + + I SI+I C + ++ + + + Sbjct: 2029 NAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHC--TAKAAPLPSVRWVLGDG 2086 Query: 1420 QEIDTTEWI--SVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKET 1477 +I ++++ ++ I+NL S R+ A N V + + + Sbjct: 2087 TQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANA 2146 Query: 1478 KIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR----- 1532 +I T P + ++L C G P P++ W K++ A ++++R Sbjct: 2147 RI---TGTSP-RRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFA 2202 Query: 1533 -XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C+A N G+ V + KP E+ K G + Sbjct: 2203 NGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLK 2262 Query: 1592 VTAVIEGIPPPEVIWYKNGNKLEN----DKEYNITTKE----KTSVIRIKELKRSHSSKY 1643 V V G+P PE+ W L N + TK + E+ Y Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDY 2322 Query: 1644 TIEASNTAGTSSVEVTLKVYDKPS 1667 T A N G + V +KV P+ Sbjct: 2323 TCFAENQVGKDEMRVRVKVVTAPA 2346 Score = 64.9 bits (151), Expect = 2e-08 Identities = 57/240 (23%), Positives = 102/240 (42%), Gaps = 21/240 (8%) Query: 733 EPPQVIEPLKSMIVRQGES-VILSAQVVGNPRPTITWCKNNKPVKALPT----KSDGDTH 787 E PQ++ + E+ + + G P+P +TW K + P + + + Sbjct: 1851 EKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN 1910 Query: 788 SITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEK 847 +++ +V+D G Y A N G+ +++V +P + + +Q++TV Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTV-----QQPQILASHYQDVTVYLG 1965 Query: 848 GTIKLVARVTRNPVPSITWY----RNNEIISPSET-ITQNFDGENIELVITNVDSEIDSG 902 TI + P P I+W R + +SP E+ IT + EN L I S D G Sbjct: 1966 DTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLH---ENRTLSIKEA-SFSDRG 2021 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC--QTSHTVSTKW 960 YKCVASN+AG S R+ + + ++ G ++ + C + + S +W Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRW 2081 Score = 63.3 bits (147), Expect = 7e-08 Identities = 149/672 (22%), Positives = 238/672 (35%), Gaps = 63/672 (9%) Query: 1047 VVWER--DGEIIKPKKNKYDFE--KRGHIRKLYIRNTSVHDEGEYSCILR-----DESCT 1097 V W + G ++ P FE K G L IR V D G+Y C D Sbjct: 1885 VTWTKVSTGALMTPNTRIQRFEVLKNG---TLVIRKVQVQDRGQYMCTASNLHGLDRMVV 1941 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRW-FKDGSEIQFSNHIQL 1154 V+ P + + Q+ V G+ E L KG + W F D Q + ++ Sbjct: 1942 LLSVTVQQPQILASHYQDVTVYLGDTIAMEC-LAKGTPAPQISWIFPDRRVWQTVSPVES 2000 Query: 1155 TID-GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEE-----PSINFTLRLPEFILV 1208 I + + L I + D G Y C N+ L + P + +L E I + Sbjct: 2001 RITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKL-ENISL 2059 Query: 1209 PANTDAYLTVEIPDETL-DVTWYKKKSVIEDTEKFTL--ISDVKKRTLIIRKCTEDDQCE 1265 P ++ L V W +F + TL IR D Sbjct: 2060 PPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGR 2119 Query: 1266 YTCVLLD----AKSTTKLKVEVVEFPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDE 1320 Y CV + A+ T +L V+ +I R ++ G + L P P Sbjct: 2120 YECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRIL 2179 Query: 1321 WIVNSKIIKKCKHTKPSIDSK-----SASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 W + SK + S DS+ + +L +K V + DAG Y N G V + V Sbjct: 2180 WRLPSKRMIDALF---SFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKV 2236 Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITK 1435 ++ K P K E + + D + + + + + D + V + + Sbjct: 2237 DVVMK---PAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGS---LVNSFMQ 2290 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK--VIK-ETKIQSPTVEKP--LKN 1490 + S K + NEV + + + T + + V K E +++ V P ++N Sbjct: 2291 SDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRN 2350 Query: 1491 IT----TEPNEDI-ELTCIFGGVPQPKVTWYRDGKK-LKTAKATYE--NRXXXXXXXXXX 1542 T P D+ + C G P PKVTW K + T+ Y+ Sbjct: 2351 KTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQR 2410 Query: 1543 XXXXXYKCIAFNDHGEVETSCVVGIQ-QKPVITISNEDIKQKHKV---GDEWLVTAVIEG 1598 Y C+ N GE + + + Q P I + I ++ G L+ EG Sbjct: 2411 SDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEG 2470 Query: 1599 IPPPEVIW-YKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 IP P V+W + G L N T + I+ L++S S + A N G + + Sbjct: 2471 IPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLI 2530 Query: 1658 VTLKVYDKPSKP 1669 + L V + KP Sbjct: 2531 LQLTVLEPMEKP 2542 Score = 60.5 bits (140), Expect = 5e-07 Identities = 109/493 (22%), Positives = 186/493 (37%), Gaps = 69/493 (13%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 + +E +YT + + ++ + D++ V K + + A I + P G V C+ Sbjct: 2316 MREEGDYTCFAENQVGK--DEMRVRVKVVT---APATIRNKTYLAVQVPYGDVVTVACEA 2370 Query: 534 EGYPRPQITWFRQTAIIKP--SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 +G P P++TW T + P S+ +Q+Y D TL+I++ D+G +TC+ +N+AG Sbjct: 2371 KGEPMPKVTWLSPTNKVIPTSSEKYQIYQD----GTLLIQKAQRSDSGNYTCLVRNSAGE 2426 Query: 592 ASSTT--ELIVEAP-LSDHGSEMTVXXXXXXXXXXXXADI-LEGIPPTFSKKPKAQYV-D 646 T + V+ P ++ + + +T D EGIP P+ + Sbjct: 2427 DRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIP-----TPRVLWAFP 2481 Query: 647 EGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEG 706 EG V +P P + G I N S+ I S ++K Sbjct: 2482 EG---------VVLPAP-----YYGNRITVHGNGSLDIRS-------------LRKSDSV 2514 Query: 707 TYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ-GESVILSAQVVGNPRPT 765 +A N GEA L + L + E P +P+ I G ++ L+ G P P+ Sbjct: 2515 QLVCMARNEGGEARLILQLTV-LEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPS 2573 Query: 766 ITW-------CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA 818 + W ++ + ++ K+DG H + D G Y A N+ G E Sbjct: 2574 LVWVLPNGTDLQSGQQLQRFYHKADGMLH----ISGLSSVDAGAYRCVARNAAGHTERLV 2629 Query: 819 VITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI-ISPSE 877 + V E N + + N +++ T+KL +W N + + + Sbjct: 2630 SLKVGLKPEANKQ---YHNL---VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQ 2683 Query: 878 TITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKS 937 T+ + +N L + S D G Y C G S V + Sbjct: 2684 TLGRVSLLDNGTLTVREA-SVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPV 2742 Query: 938 YETEEGKTVILEC 950 T G TV L C Sbjct: 2743 IYTRPGNTVKLNC 2755 Score = 54.4 bits (125), Expect = 3e-05 Identities = 63/288 (21%), Positives = 113/288 (39%), Gaps = 20/288 (6%) Query: 831 EPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR--NNEIISPSETITQNFDG-EN 887 +P + Q ++V + T P P +TW + +++P+ I Q F+ +N Sbjct: 1852 KPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRI-QRFEVLKN 1910 Query: 888 IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVI 947 LVI V + D G Y C ASN G +++ V++ + + G T+ Sbjct: 1911 GTLVIRKVQVQ-DRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIA 1969 Query: 948 LECQTSHTVSTK--WYHNKKE----ISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIV 1001 +EC T + + W + +S ++ R + E R D GV KC+ Sbjct: 1970 MECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENR--TLSIKEASFSDRGVYKCVA 2027 Query: 1002 KDQETSTMLVVK---ETIPEFIRKLQDFEVKEKDVAILEVEINSETA---DVVWE-RDGE 1054 + + L ++ +P I + + + + + ++ A V W DG Sbjct: 2028 SNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGT 2087 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 I+P + + LYIRN + D G Y C+ + +A TV Sbjct: 2088 QIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTV 2135 Score = 49.6 bits (113), Expect = 0.001 Identities = 65/278 (23%), Positives = 104/278 (37%), Gaps = 23/278 (8%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G I L C P P + W+ D ++ H +L I+ + G Sbjct: 2557 GHTISLNCSAAGTPTPSLVWVLPNGT---DLQSGQQLQRFYHKADGMLHISGLSSVDAGA 2613 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y VA N G + LK+ + E + L S+I GE++ L G + + Sbjct: 2614 YRCVARNAAGHTERLVSLKVGL-KPEANKQYHNLVSII--NGETLKLPCTPPGAGQGRFS 2670 Query: 768 WCKNN----KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSA-VITV 822 W N + + L S D ++T+ + V D G Y + E G + TS VI + Sbjct: 2671 WTLPNGMHLEGPQTLGRVSLLDNGTLTV-REASVFDRGTYVCRMETEYGPSVTSIPVIVI 2729 Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 P +EP I + T+KL P ITW ++ + + Sbjct: 2730 AYPPRITSEPT------PVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARL 2783 Query: 883 FDGENIE----LVITNVDSEIDSGDYKCVASNSAGKSS 916 + + L I + ++ D+G YKC+A N G S Sbjct: 2784 YGNRFLHPQGSLTIQHA-TQRDAGFYKCMAKNILGSDS 2820 Score = 46.8 bits (106), Expect = 0.007 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 1/80 (1%) Query: 524 GSTVQFECQVEGYPRPQITW-FRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFT 582 G T+ EC +G P PQI+W F + + + TL I+E D G + Sbjct: 1965 GDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYK 2024 Query: 583 CVAKNAAGFASSTTELIVEA 602 CVA NAAG S L V A Sbjct: 2025 CVASNAAGADSLAIRLHVAA 2044 Score = 46.0 bits (104), Expect = 0.011 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 8/99 (8%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQT--AIIKPSQDFQMYYDDDNVATLVIREVFPEDA 578 T + TV F C+ G P+P +TW + + A++ P+ Q + N TLVIR+V +D Sbjct: 1866 TAETDTV-FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN-GTLVIRKVQVQDR 1923 Query: 579 GTFTCVAKNAAGFASSTT--ELIVEAP--LSDHGSEMTV 613 G + C A N G + V+ P L+ H ++TV Sbjct: 1924 GQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTV 1962 Score = 44.0 bits (99), Expect = 0.046 Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 8/130 (6%) Query: 474 LMDENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQV 533 + D Y ++ + + +PV + P V RP G+TV+ C Sbjct: 2703 VFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRP-----GNTVKLNCMA 2757 Query: 534 EGYPRPQITW-FRQTAIIKPSQDFQMYYDD--DNVATLVIREVFPEDAGTFTCVAKNAAG 590 G P+ ITW + +K ++Y + +L I+ DAG + C+AKN G Sbjct: 2758 MGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILG 2817 Query: 591 FASSTTELIV 600 S TT + V Sbjct: 2818 SDSKTTYIHV 2827 Score = 42.7 bits (96), Expect = 0.11 Identities = 58/241 (24%), Positives = 92/241 (38%), Gaps = 28/241 (11%) Query: 1486 KPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK-KLKTAKATYEN-----RXXXXXXX 1539 K + ++ D C G P+P VTW + L T + Sbjct: 1858 KSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRK 1917 Query: 1540 XXXXXXXXYKCIAFNDHG--EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y C A N HG + V +QQ ++ +D+ +GD + + + Sbjct: 1918 VQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVY--LGDTIAMECLAK 1975 Query: 1598 GIPPPEVIWYKNGNKL---ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 G P P++ W ++ + E IT E + + IKE S Y ASN AG Sbjct: 1976 GTPAPQISWIFPDRRVWQTVSPVESRITLHENRT-LSIKEASFSDRGVYKCVASNAAGAD 2034 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP-DNNRW 1713 S+ + L V P PVI +E E++++ PP GL + + K P + RW Sbjct: 2035 SLAIRLHVAALP-----PVIHQE-KLENISL---PP----GLSIHIHCTAKAAPLPSVRW 2081 Query: 1714 I 1714 + Sbjct: 2082 V 2082 Score = 39.9 bits (89), Expect = 0.75 Identities = 51/220 (23%), Positives = 91/220 (41%), Gaps = 22/220 (10%) Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV-----LKI 697 Q V EG L C + A P I W ++PD +I A D S+ L+I Sbjct: 489 QTVLEGGPCQLSCNVKASESPSIFW------VLPDGSILKAPMDDPDSKFSILSSGWLRI 542 Query: 698 TNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQ 757 +++ G Y +A R+ + + +++ +P + + ++ GESV L Sbjct: 543 KSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAE--KDTVTIGKNPGESVTLPCN 600 Query: 758 VVGNPRPTITWCKNNKPV--KALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIA 814 + P ++W N+ + T + T+ PK +V D G Y A N +G Sbjct: 601 ALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGAD 660 Query: 815 ETSAVITVEE-----PTEENAEP-PLFINRFQEITVKEKG 848 + ITV + P++ P ++R +E V+++G Sbjct: 661 HFTVGITVTKKGSGLPSKRGRRPGAKALSRVREDIVEDEG 700 Score = 39.9 bits (89), Expect = 0.75 Identities = 38/155 (24%), Positives = 69/155 (44%), Gaps = 8/155 (5%) Query: 1233 KSVIEDTE-KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV 1291 K+ ++D + KF+++S R I+ D Y C+ ++ V+ P Sbjct: 522 KAPMDDPDSKFSILSSGWLR---IKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQ 578 Query: 1292 DYERE-YRIKR--GSDVTLLVDYQAFPQPNDEWIV-NSKIIKKCKHTKPSIDSKSASLTI 1347 E++ I + G VTL + A P+ + WI+ N +II +T + +L+I Sbjct: 579 PAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSI 638 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS 1382 KV+ +D+G Y+ N G + +T+ K S Sbjct: 639 PKVQVSDSGYYRCVAVNQQGADHFTVGITVTKKGS 673 >UniRef50_UPI000155E24A Cluster: PREDICTED: similar to myosin binding protein H-like; n=4; Eutheria|Rep: PREDICTED: similar to myosin binding protein H-like - Equus caballus Length = 507 Score = 94.3 bits (224), Expect = 3e-17 Identities = 63/290 (21%), Positives = 127/290 (43%), Gaps = 19/290 (6%) Query: 1297 YRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAG 1356 Y K G V LL+ +Q P+P W + + + + + + + L I++ + D+G Sbjct: 63 YIRKVGDTVNLLIPFQGKPKPRATWTCDGCALDASRVSVRN-GERDSILFIREAQRADSG 121 Query: 1357 IYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 Y+L ++ A +++ ++++P PP ++++ S+ + W P++TGN ++ Y Sbjct: 122 RYQLSVQLGELEATATIDILVIERPGPPQSIKLVDVWGSNAILEWTPPQDTGNVALLGYT 181 Query: 1417 VEYQEIDTTEWISV-KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE-TTEYYKVI 1474 V+ + + W +V + +T ++ L +SY FR +A N+ +S+ + T + + Sbjct: 182 VQKADTKSGLWFTVLERYHRTSCTVSKLIVGNSYAFRVFAENQCGLSETAPITADLAHIQ 241 Query: 1475 KETKI------------QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL 1522 K + ++P +PL + TT D +L C P+PK+ W ++ + Sbjct: 242 KAATVYKTEGFAQRDFSEAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDI 301 Query: 1523 ----KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQ 1568 K T+ Y C A N GE C V ++ Sbjct: 302 QGNPKYRALTHLGICSLEIRKPGPFDRGIYTCKAVNPLGEASVDCRVDVK 351 Score = 78.6 bits (185), Expect = 2e-12 Identities = 45/168 (26%), Positives = 82/168 (48%), Gaps = 5/168 (2%) Query: 1585 KVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYT 1644 KVGD + +G P P W +G L+ + ++ E+ S++ I+E +R+ S +Y Sbjct: 66 KVGDTVNLLIPFQGKPKPRATWTCDGCALDASR-VSVRNGERDSILFIREAQRADSGRYQ 124 Query: 1645 IEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIE 1704 + ++ + + V ++P P+ + + ++ + +EW PP D G + L Y ++ Sbjct: 125 LSVQLGELEATATIDILVIERPGPPQS-IKLVDVWGSNAILEWTPPQDTGNVALLGYTVQ 183 Query: 1705 KHEPDNNRWIKVADVDRDVETYC-IQKLNENCEYMFRVIAQNPVGFSE 1751 K + + W V ++R T C + KL Y FRV A+N G SE Sbjct: 184 KADTKSGLWFTV--LERYHRTSCTVSKLIVGNSYAFRVFAENQCGLSE 229 Score = 50.8 bits (116), Expect = 4e-04 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 11/134 (8%) Query: 1932 EKDEIIFRISAENTVGVSLPTESQSVRLEKHATV-------PSPPTAPLEIRMVGSNIVM 1984 E+D I+F A+ Q LE AT+ P PP + + + GSN ++ Sbjct: 105 ERDSILFIREAQRADSGRYQLSVQLGELEATATIDILVIERPGPPQSIKLVDVWGSNAIL 164 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 W P+ G LLGY + D +W V + + + L ++Y R++A Sbjct: 165 -EWTPPQDTGNVALLGYTVQKADTKSGLWFTVLE-RYHRTSCTVSKLIVGNSYAFRVFAE 222 Query: 2045 NEIGLSE--PLESD 2056 N+ GLSE P+ +D Sbjct: 223 NQCGLSETAPITAD 236 Score = 44.0 bits (99), Expect = 0.046 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 1/87 (1%) Query: 507 SMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVA 566 S AP F + L T G Q C V P+P+I W + I+ + ++ + Sbjct: 258 SEAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDIQGNPKYRA-LTHLGIC 316 Query: 567 TLVIREVFPEDAGTFTCVAKNAAGFAS 593 +L IR+ P D G +TC A N G AS Sbjct: 317 SLEIRKPGPFDRGIYTCKAVNPLGEAS 343 Score = 41.1 bits (92), Expect = 0.33 Identities = 31/95 (32%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH----S 788 E P+ +PL G L V +P+P I W KN ++ P K TH S Sbjct: 259 EAPKFSQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKIDIQGNP-KYRALTHLGICS 317 Query: 789 ITILKPKKVKDEGVYTLKAENSEGIAETSAVITVE 823 + I KP D G+YT KA N G A + V+ Sbjct: 318 LEIRKPGPF-DRGIYTCKAVNPLGEASVDCRVDVK 351 Score = 37.1 bits (82), Expect = 5.3 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 7/104 (6%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHE- 1924 P P++ + + + L+WT P+ G + Y ++ K W TV H Sbjct: 146 PGPPQSIKLVDVWGSNAILEWTPPQDTGNVALLGYTVQKADTKSGLW---FTVLERYHRT 202 Query: 1925 HC-IENIKEKDEIIFRISAENTVGVS--LPTESQSVRLEKHATV 1965 C + + + FR+ AEN G+S P + ++K ATV Sbjct: 203 SCTVSKLIVGNSYAFRVFAENQCGLSETAPITADLAHIQKAATV 246 >UniRef50_UPI0000E472F6 Cluster: PREDICTED: similar to myosin light chain kinase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to myosin light chain kinase - Strongylocentrotus purpuratus Length = 1627 Score = 94.3 bits (224), Expect = 3e-17 Identities = 66/238 (27%), Positives = 99/238 (41%), Gaps = 8/238 (3%) Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 D+ P + P EQ+ P F +K + DG V E + G + W R I Sbjct: 1071 DEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVD 1130 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV--EAPLSDHGSE 610 ++F+ Y N+ L I E+FPED+G +TC A N G + + + V E +S S+ Sbjct: 1131 CKEFR-YVSRGNIYQLEIAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQ 1189 Query: 611 -MTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLF 669 M V + IPP F ++P++Q V+EG+ + C + P P + W Sbjct: 1190 SMDVDVSLSTDMPCTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSK 1249 Query: 670 KGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 G S+ + H L+I N + G Y A N EGE L I Sbjct: 1250 DGRPFTDGGRFSIRSDKFTH----TLEIQNARSTDAGVYACTARNSEGEVVCEFTLDI 1303 Score = 87.8 bits (208), Expect = 3e-15 Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 9/220 (4%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSAS-L 1345 PPK + +E +V L Q P P +W V++K I+ K ++D+ S L Sbjct: 1375 PPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSRL 1434 Query: 1346 TIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK----PSPPGKPNILEIDSSSINICW 1401 TI + D+G+Y+ N+ G A + + K +P GKP + + +S I W Sbjct: 1435 TISEAFAEDSGVYRCEATNSSGTASTSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITW 1494 Query: 1402 DEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDI 1461 P G S I Y V+ ++ T W V N+T+T + + Y +R A NE Sbjct: 1495 AAPAEDGGSPIFNYKVDGRKAKETGWTEVANVTQTSFEVTGIVPGVEYVYRVSAENEAGW 1554 Query: 1462 SDASETTEYYKVIKETKI---QSPTVEKPLKNITTEPNED 1498 S ++ ++ VI E++ S + +KP + PN+D Sbjct: 1555 SPSTAISD-RAVITESESPPKTSSSTDKPPVVKDSPPNKD 1593 Score = 86.6 bits (205), Expect = 7e-15 Identities = 52/184 (28%), Positives = 90/184 (48%), Gaps = 6/184 (3%) Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT-KEKTSVIRIKELKRSHSSKYTIE 1646 DE ++ ++G+P P V W+ + ++E+DK IT + S + I E S Y E Sbjct: 1391 DEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCE 1450 Query: 1647 ASNTAGTSSVEVTLKVYDK---PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 A+N++GT+S L V K P P G + + S+ S I W P +DGG + Y + Sbjct: 1451 ATNSSGTASTSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKV 1510 Query: 1704 EKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTA 1763 + + W +VA+V + ++ + + EY++RV A+N G+S + + T Sbjct: 1511 DGRKAKETGWTEVANVTQ--TSFEVTGIVPGVEYVYRVSAENEAGWSPSTAISDRAVITE 1568 Query: 1764 LDVP 1767 + P Sbjct: 1569 SESP 1572 Score = 82.6 bits (195), Expect = 1e-13 Identities = 67/258 (25%), Positives = 107/258 (41%), Gaps = 23/258 (8%) Query: 477 ENNYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGY 536 E + ++ +E++ E S + P F LR K DG + C V+G Sbjct: 513 EGGSARSMESSEDERVVSRSKIEPVRSGSRVQLPFFSLPLRRKTVYDGEPARISCNVQGT 572 Query: 537 PRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTT 596 P+P+I+W + I + + Y VA + IR D GTF C AKNA G A+S Sbjct: 573 PKPKISWSKNGVPIYDGTFYNITYRW-GVAMVEIRHASKSDTGTFRCTAKNAEGEATSAC 631 Query: 597 ELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECR 656 EL+VE + +E + I P+F+K + EG + LE + Sbjct: 632 ELVVEQRVPRSETE-------------------DYIRPSFAKPLRRIRAKEGRKVRLEIQ 672 Query: 657 LVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNRE 716 ++ PEP + WL ++V +++ V L I V G Y +A + Sbjct: 673 VMGWPEPKVTWLKDNVDVVHSDHMYV---EKFPNGLQSLVIYRVVPTDAGRYQAIASSPA 729 Query: 717 GEASLPIVLKIKTGEKEP 734 G+A+ + + GE P Sbjct: 730 GKATCSADVDVIPGEALP 747 Score = 79.4 bits (187), Expect = 1e-12 Identities = 57/197 (28%), Positives = 92/197 (46%), Gaps = 20/197 (10%) Query: 740 PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-------- 791 PL+ V GE +S V G P+P I+W KN P+ DG ++IT Sbjct: 551 PLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIY------DGTFYNITYRWGVAMVE 604 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEE--PTEENAE--PPLFINRFQEITVKEK 847 ++ D G + A+N+EG A ++ + VE+ P E + P F + I KE Sbjct: 605 IRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIRAKEG 664 Query: 848 GTIKLVARVTRNPVPSITWYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 ++L +V P P +TW ++N +++ + F LVI V D+G Y+ Sbjct: 665 RKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRV-VPTDAGRYQA 723 Query: 907 VASNSAGKSSHGARVTI 923 +AS+ AGK++ A V + Sbjct: 724 IASSPAGKATCSADVDV 740 Score = 69.3 bits (162), Expect = 1e-09 Identities = 33/99 (33%), Positives = 54/99 (54%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYD 561 T ++ P F+ L+ ++ + V EC V+G P P + WF I+ + + D Sbjct: 1368 TDSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMD 1427 Query: 562 DDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 +D V+ L I E F ED+G + C A N++G AS++ EL+V Sbjct: 1428 NDGVSRLTISEAFAEDSGVYRCEATNSSGTASTSGELMV 1466 Score = 65.3 bits (152), Expect = 2e-08 Identities = 59/210 (28%), Positives = 89/210 (42%), Gaps = 31/210 (14%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPV---KALPTKSDGDTHSIT 790 PP + + M +R GE V+L + G+ + W +N + + K S G+ + + Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLE 1146 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITV-EEPT----------------------- 826 I + +D G YT +A N G +E SA+ITV EEP+ Sbjct: 1147 IAEIFP-EDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMPCTA 1205 Query: 827 --EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD 884 +E+ PP F Q V+E T V +PVPS+TW ++ + + D Sbjct: 1206 TMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSIRSD 1265 Query: 885 GENIELVITNVDSEIDSGDYKCVASNSAGK 914 L I N S D+G Y C A NS G+ Sbjct: 1266 KFTHTLEIQNARS-TDAGVYACTARNSEGE 1294 Score = 64.1 bits (149), Expect = 4e-08 Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 37/212 (17%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+F KK + + +G ++LE + D+ WL G++IV + +++ Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQ-- 1144 Query: 693 SVLKITNVKKFQEGTYT--------------VVAVNREGEASLPIVLKIK---------- 728 L+I + G YT ++ VN E S+ I + Sbjct: 1145 --LEIAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMP 1202 Query: 729 ---TGEKE--PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVK---ALPT 780 T +++ PP+ E +S +V +G + + + V G+P P++TW K+ +P Sbjct: 1203 CTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSI 1262 Query: 781 KSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 +SD TH++ I + D GVY A NSEG Sbjct: 1263 RSDKFTHTLEIQNARST-DAGVYACTARNSEG 1293 Score = 63.7 bits (148), Expect = 5e-08 Identities = 54/200 (27%), Positives = 84/200 (42%), Gaps = 16/200 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P FS + + V +G + C + P+P I+W G I ++ + M Sbjct: 546 PFFSLPLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIYDGTFYNITYRWGVAM--- 602 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEAS----LPIVLKIKTGEKEP---PQVIEPLKSMIV 746 ++I + K GT+ A N EGEA+ L + ++ E E P +PL+ + Sbjct: 603 -VEIRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIRA 661 Query: 747 RQGESVILSAQVVGNPRPTITWCKNNKPV----KALPTKSDGDTHSITILKPKKVKDEGV 802 ++G V L QV+G P P +TW K+N V K S+ I + D G Sbjct: 662 KEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRVVPT-DAGR 720 Query: 803 YTLKAENSEGIAETSAVITV 822 Y A + G A SA + V Sbjct: 721 YQAIASSPAGKATCSADVDV 740 Score = 62.1 bits (144), Expect = 2e-07 Identities = 36/114 (31%), Positives = 57/114 (50%), Gaps = 3/114 (2%) Query: 501 PTSE-EQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY 559 P SE E + P F + LR +G V+ E QV G+P P++TW + + S + Sbjct: 640 PRSETEDYIRPSFAKPLRRIRAKEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVE 699 Query: 560 YDDDNVATLVIREVFPEDAGTFTCVAKNAAGFA--SSTTELIVEAPLSDHGSEM 611 + + +LVI V P DAG + +A + AG A S+ ++I L D G ++ Sbjct: 700 KFPNGLQSLVIYRVVPTDAGRYQAIASSPAGKATCSADVDVIPGEALPDRGGDV 753 Score = 62.1 bits (144), Expect = 2e-07 Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 4/116 (3%) Query: 1837 FRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSP 1896 +R A N GT+ TS + + GK + P + V +++ S + W P +GGSP Sbjct: 1447 YRCEATNSSGTAS--TSGELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSP 1504 Query: 1897 ITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 I NY ++ + K WT++ V + E + I E ++R+SAEN G S T Sbjct: 1505 IFNYKVDGRKAKETGWTEVANVTQTSFE--VTGIVPGVEYVYRVSAENEAGWSPST 1558 Score = 58.0 bits (134), Expect = 3e-06 Identities = 32/133 (24%), Positives = 68/133 (51%), Gaps = 6/133 (4%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP + Q+ + G + E+ +T + V W ++G +I + G +L+ Sbjct: 1087 PPSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLE 1146 Query: 1165 IYDCDLDDAGEYSCEV----GNSKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVE 1219 I + +D+G+Y+CE G S+C+A++TV EEPS++ ++ + V +TD T Sbjct: 1147 IAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVDVSLSTDMPCTAT 1206 Query: 1220 IPDETLDVTWYKK 1232 + ++ + ++++ Sbjct: 1207 MDEDHIPPEFFEE 1219 Score = 58.0 bits (134), Expect = 3e-06 Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 4/155 (2%) Query: 1896 PITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQ 1955 P + + K ++ + I V I +D ++R A N+ G + + S Sbjct: 1405 PTVKWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCEATNSSGTA--STSG 1462 Query: 1956 SVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWME 2015 + + VP P ++ +W P DGG+P+ Y + R +T W E Sbjct: 1463 ELMVAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTE 1522 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLS 2050 V +V F + + Y+ R+ A NE G S Sbjct: 1523 V--ANVTQTSFEVTGIVPGVEYVYRVSAENEAGWS 1555 Score = 55.2 bits (127), Expect = 2e-05 Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 3/153 (1%) Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTE-ENAEPPLFINRFQEITVKEKGTIKLVARVT 857 DE A ++ G+A P E E A PP F +FQ++++++ + L +T Sbjct: 1053 DEFTMRTYAPSATGVAADDEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVVIT 1112 Query: 858 RNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 + + W RN + I + G +L I + E DSG Y C A N G+S Sbjct: 1113 GSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPE-DSGKYTCEALNDHGESEC 1171 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 A +T++ E + + +S + + + + C Sbjct: 1172 SAMITVNEEPSVSIS-ISQSMDVDVSLSTDMPC 1203 Score = 54.4 bits (125), Expect = 3e-05 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 6/108 (5%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEI-NSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLY 1075 P F +K QD +++ + +LEV I S DV W R+G+ I K ++ + RG+I +L Sbjct: 1088 PSFDKKFQDMSIRDGERVVLEVVITGSRPMDVGWLRNGQDIVDCK-EFRYVSRGNIYQLE 1146 Query: 1076 IRNTSVHDEGEYSC-ILRD---ESCTAEVTVVELPPEIITRLQNQKVN 1119 I D G+Y+C L D C+A +TV E P I+ Q+ V+ Sbjct: 1147 IAEIFPEDSGKYTCEALNDHGESECSAMITVNEEPSVSISISQSMDVD 1194 Score = 53.6 bits (123), Expect = 6e-05 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 2/110 (1%) Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIIS 874 E++ ++ + + PP F+ QE E+ + L V P+P++ W+ +N+ I Sbjct: 1358 ESTTGVSGSDTDSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIE 1417 Query: 875 PSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + + D + + L I+ +E DSG Y+C A+NS+G +S + + Sbjct: 1418 SDKFVVITMDNDGVSRLTISEAFAE-DSGVYRCEATNSSGTASTSGELMV 1466 Score = 53.6 bits (123), Expect = 6e-05 Identities = 56/242 (23%), Positives = 97/242 (40%), Gaps = 11/242 (4%) Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 D EG PP F + + +Y E +++LEC + +P P + W +EI D+ + + +++ Sbjct: 1369 DSQEGGPPKFLRGLQEEYAWEEDEVVLECHVQGVPMPTVKWFVHNKEIESDKFVVITMDN 1428 Query: 687 DMHMYCSVLKITNVKKFQE--GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLK 742 D V ++T + F E G Y A N G AS L + G+ P+ +P Sbjct: 1429 D-----GVSRLTISEAFAEDSGVYRCEATNSSGTASTSGELMV-AGKVVVPKAPGGKPKV 1482 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP-TKSDGDTHSITILKPKKVKDEG 801 + + +A P + + + K T+ T + + E Sbjct: 1483 EQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTEVANVTQTSFEVTGIVPGVEY 1542 Query: 802 VYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 VY + AEN G + ++A+ TE + P + + VK+ K A P Sbjct: 1543 VYRVSAENEAGWSPSTAISDRAVITESESPPKTSSSTDKPPVVKDSPPNKDQAGKGPGPK 1602 Query: 862 PS 863 PS Sbjct: 1603 PS 1604 Score = 50.8 bits (116), Expect = 4e-04 Identities = 42/208 (20%), Positives = 85/208 (40%), Gaps = 14/208 (6%) Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA---KATYE-NR 1532 +++Q P PL+ T E ++C G P+PK++W ++G + TY Sbjct: 541 SRVQLPFFSLPLRRKTVYDGEPARISCNVQGTPKPKISWSKNGVPIYDGTFYNITYRWGV 600 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ---------K 1583 ++C A N GE ++C + ++Q+ + + + I+ + Sbjct: 601 AMVEIRHASKSDTGTFRCTAKNAEGEATSACELVVEQRVPRSETEDYIRPSFAKPLRRIR 660 Query: 1584 HKVGDEWLVTAVIEGIPPPEVIWYK-NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 K G + + + G P P+V W K N + + +D Y + I + + + + Sbjct: 661 AKEGRKVRLEIQVMGWPEPKVTWLKDNVDVVHSDHMYVEKFPNGLQSLVIYRVVPTDAGR 720 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPE 1670 Y AS+ AG ++ + V + P+ Sbjct: 721 YQAIASSPAGKATCSADVDVIPGEALPD 748 Score = 50.8 bits (116), Expect = 4e-04 Identities = 31/136 (22%), Positives = 58/136 (42%), Gaps = 4/136 (2%) Query: 1445 TNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCI 1504 ++ + R YA + ++ E EY + + P+ +K ++++ E + L + Sbjct: 1051 SDDEFTMRTYAPSATGVAADDEEPEYSAPEEPEQAGPPSFDKKFQDMSIRDGERVVLEVV 1110 Query: 1505 FGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXX---XXXYKCIAFNDHGEVE 1560 G V W R+G+ + K Y +R Y C A NDHGE E Sbjct: 1111 ITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPEDSGKYTCEALNDHGESE 1170 Query: 1561 TSCVVGIQQKPVITIS 1576 S ++ + ++P ++IS Sbjct: 1171 CSAMITVNEEPSVSIS 1186 Score = 48.8 bits (111), Expect = 0.002 Identities = 25/81 (30%), Positives = 40/81 (49%) Query: 1587 GDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G+ ++ VI G P +V W +NG + + KE+ ++ + I E+ S KYT E Sbjct: 1102 GERVVLEVVITGSRPMDVGWLRNGQDIVDCKEFRYVSRGNIYQLEIAEIFPEDSGKYTCE 1161 Query: 1647 ASNTAGTSSVEVTLKVYDKPS 1667 A N G S + V ++PS Sbjct: 1162 ALNDHGESECSAMITVNEEPS 1182 Score = 48.8 bits (111), Expect = 0.002 Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 1093 DESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSN 1150 D CTA + +PPE Q+Q V +G A F ++ GD + + W KDG Sbjct: 1200 DMPCTATMDEDHIPPEFFEEPQSQMVEEGTTAVFTCDV-DGDPVPSLTWSKDGRPFTDGG 1258 Query: 1151 HIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 + D L+I + DAG Y+C NS+ Sbjct: 1259 RFSIRSDKFTHTLEIQNARSTDAGVYACTARNSE 1292 Score = 48.8 bits (111), Expect = 0.002 Identities = 42/194 (21%), Positives = 76/194 (39%), Gaps = 9/194 (4%) Query: 1700 KYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV 1759 K+ + E ++++++ + + V I + ++R A N G A S ++ Sbjct: 1408 KWFVHNKEIESDKFVVITMDNDGVSRLTISEAFAEDSGVYRCEATNSSG--TASTSGELM 1465 Query: 1760 IKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVE-IKQEGKKWKXXXX 1818 + + VP S ITW ++GGSPI +YKV+ K + W Sbjct: 1466 VAGKVVVPKAPGGKPKVEQASKTSFKITWAAPAEDGGSPIFNYKVDGRKAKETGWTEVAN 1525 Query: 1819 XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST 1878 + + Y +R+ A NE G S D+ I ++ +PP S ST Sbjct: 1526 VTQTSFEVTGIVPGVEYVYRVSAENEAGWSPSTAISDRAVITESESPPK------TSSST 1579 Query: 1879 SRSVTLKWTEPESN 1892 + +K + P + Sbjct: 1580 DKPPVVKDSPPNKD 1593 Score = 39.1 bits (87), Expect = 1.3 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKK-QK 1162 PP+ + LQ + + ++ E + +G + V+WF EI+ + +T+D + Sbjct: 1375 PPKFLRGLQEEYAWEEDEVVLECHV-QGVPMPTVKWFVHNKEIESDKFVVITMDNDGVSR 1433 Query: 1163 LKIYDCDLDDAGEYSCEVGNSKCTA 1187 L I + +D+G Y CE NS TA Sbjct: 1434 LTISEAFAEDSGVYRCEATNSSGTA 1458 Score = 37.9 bits (84), Expect = 3.0 Identities = 40/188 (21%), Positives = 71/188 (37%), Gaps = 14/188 (7%) Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 V EG E+SE S + + P F + TV + ++ V Sbjct: 510 VDSEGGSARSMESSEDERVVSRSKIEPVRSGSRVQLPFFSLPLRRKTVYDGEPARISCNV 569 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P I+W +N I + + +V S+ D+G ++C A N+ G+++ Sbjct: 570 QGTPKPKISWSKNGVPIYDGTFYNITYRW-GVAMVEIRHASKSDTGTFRCTAKNAEGEAT 628 Query: 917 HGARVTI----------DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK--WYHNK 964 + + D + +F K L++ +EG+ V LE Q K W + Sbjct: 629 SACELVVEQRVPRSETEDYIRPSFAKPLRR-IRAKEGRKVRLEIQVMGWPEPKVTWLKDN 687 Query: 965 KEISGMDH 972 ++ DH Sbjct: 688 VDVVHSDH 695 Score = 36.3 bits (80), Expect = 9.2 Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 2/110 (1%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+ + + ++ G+ D P P+ W + + D + +L Sbjct: 1213 PPEFFEEPQSQMVEEGTTAVFTCDVDGDPVPSLTWSKDGRPFTDGGRFSIRSDKFTHTLE 1272 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSS 1396 I+ +TDAG+Y N+ G E + IL P+ I D SS Sbjct: 1273 IQNARSTDAGVYACTARNSEGEVVCEFTLDIL--PTGADDKGITASDVSS 1320 >UniRef50_A4AI84 Cluster: Serine protease, subtilase family protein; n=1; marine actinobacterium PHSC20C1|Rep: Serine protease, subtilase family protein - marine actinobacterium PHSC20C1 Length = 1226 Score = 94.3 bits (224), Expect = 3e-17 Identities = 94/422 (22%), Positives = 156/422 (36%), Gaps = 25/422 (5%) Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE-SVTIEWKPPLD 1692 ++ ++ S T A + S + KP+ + P ++R SV + W P Sbjct: 509 DVGKTISITVTANAQGFSTLSKTSTSTATVTKPALTQ-PQTFGVVARPGSVDLSWTEPAS 567 Query: 1693 DGGLELTKYAIEKHEPDNNRWIKVAD-VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 GG ++ Y I+ + + D V D+ T + L Y +V A+ F Sbjct: 568 FGGT-ISDYVIQYRPTSTSTYTTYNDGVSADL-TATLAGLKFGSSYYVKVAAKTE--FGT 623 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGGSPIIDYKVEIKQEG 1810 + P+++KT PS SV + W PS NGG+ I DY V + G Sbjct: 624 GTSTSPVLVKTLTGRPSAPTGLLATAA--PRSVSLDWLTPSTSNGGT-ISDYTVRYRLSG 680 Query: 1811 KK-WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPS 1867 WK A + LS + Y+F + A+ + G+ T G P Sbjct: 681 TTTWKTFTDGVSTDTTATVTGLSGSRKYEFAVSAKTQFGSGSSATVARSTPSGVASAPTG 740 Query: 1868 QPRNFVVSESTSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHC 1926 +V + S+ L W P + NGG +T+Y I ++T +WT +V + H Sbjct: 741 -----LVGTPSLTSMELTWNSPSTTNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHT 795 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTS 1986 I + F I+A+ G S + + + S P + R + + + Sbjct: 796 ISGLTRNKSYEFAIAAKTVFGTG---SSAVLAKSTQSGIASAPKSLTATR--AATTLSLN 850 Query: 1987 WGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNE 2046 W P G + Y + R T W I L+ + +Y + +YAR Sbjct: 851 WTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTL 910 Query: 2047 IG 2048 G Sbjct: 911 AG 912 Score = 94.3 bits (224), Expect = 3e-17 Identities = 96/421 (22%), Positives = 150/421 (35%), Gaps = 20/421 (4%) Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVTLKVYDK--PSKPEGPVIMREISRESVTIEWKPP-L 1691 L S ++ + A G+ S + S P G ++ S S+ + W P Sbjct: 702 LSGSRKYEFAVSAKTQFGSGSSATVARSTPSGVASAPTG--LVGTPSLTSMELTWNSPST 759 Query: 1692 DDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE 1751 +GG +T Y+I W V D + I L N Y F + A+ G Sbjct: 760 TNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHTISGLTRNKSYEFAIAAKTVFGTGS 819 Query: 1752 ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK 1811 S + T + S S+ T PS NGG+ I DY V + G Sbjct: 820 ---SAVLAKSTQSGIASAPKSLTATRAATTLSLNWT-APSTTNGGT-ITDYIVRYRVAGT 874 Query: 1812 K-WKXXXX--XXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQ 1868 WK A I L+ + +Y +YAR GT+ S + S Sbjct: 875 TTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTLAGTTALSGSSTTLRTSTPSGVASA 934 Query: 1869 PRNFVVSESTSRSVTLKWTEPES-NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCI 1927 P V + S + S+ L W P + NGG +T+Y I ++T +WT +V + H I Sbjct: 935 PTGLVGTPSLT-SMELTWNSPSTTNGGGSVTDYSIRYRTKGTTTWTTVVDGVSTSTNHTI 993 Query: 1928 ENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 + F I+A+ G S + + + S P + R + + +W Sbjct: 994 SGLTRNKSYEFAIAAKTVFGTG---SSAVLAKSTQSGIASAPKSLTATR--AATTLSLNW 1048 Query: 1988 GTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEI 2047 P G + Y + R T W I L+ + +Y + +YAR Sbjct: 1049 TAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDVNVYARTLA 1108 Query: 2048 G 2048 G Sbjct: 1109 G 1109 Score = 37.9 bits (84), Expect = 3.0 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451 ++++++ W P T TI Y+V Y+ TT W + + T T +I L + SY Sbjct: 844 ATTLSLNWTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDV 903 Query: 1452 RAYA 1455 YA Sbjct: 904 NVYA 907 Score = 37.9 bits (84), Expect = 3.0 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 1394 SSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRF 1451 ++++++ W P T TI Y+V Y+ TT W + + T T +I L + SY Sbjct: 1041 ATTLSLNWTAPSTTNGGTITDYIVRYRVAGTTTWKTFADGVSTDTTATITGLTRSRSYDV 1100 Query: 1452 RAYA 1455 YA Sbjct: 1101 NVYA 1104 >UniRef50_UPI0000F1ECB4 Cluster: PREDICTED: similar to hemicentin 1,; n=1; Danio rerio|Rep: PREDICTED: similar to hemicentin 1, - Danio rerio Length = 413 Score = 93.9 bits (223), Expect = 4e-17 Identities = 87/324 (26%), Positives = 133/324 (41%), Gaps = 26/324 (8%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP+ S + V G D LEC+ P P + W KG+ D + E D+H Sbjct: 95 PPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQ-KGDL---DLGTAPFAEQDVHR-- 148 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L+I V++ G YT VA N G +S +VL++ P E + G+++ Sbjct: 149 GTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAA----PTFSESPVDITASVGDNI 204 Query: 753 ILSAQVVGNPRPTITWCK-NNKPVKALPTKSDGDTH---SITILKPKKVKDEGVYTLKAE 808 L G P P++ W + + +P+ + G + ++ V DEGVY +A+ Sbjct: 205 TLPCIARGFPTPSLIWRRQDGRPIFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAK 264 Query: 809 NSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRN-PVPSITWY 867 N G + A +TV EPPL + IT + L R+ P+P W Sbjct: 265 NQFGSIKALARVTV-----TGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWT 319 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 N + + + DG L + E D+G Y C A N AG S VT++V Sbjct: 320 HNGKQVRVGGRVFLRSDG---SLHVDRAVPE-DAGTYVCTAVNVAG--SANITVTVEVHA 373 Query: 928 VTFVKHLQKSYETEEGKTVILECQ 951 +K Y EG + L C+ Sbjct: 374 PPDIKAGPLHYTASEGTPISLSCE 397 Score = 77.0 bits (181), Expect = 5e-12 Identities = 84/340 (24%), Positives = 129/340 (37%), Gaps = 26/340 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P+ P+ Q G+++ + C P P + W + +S++ ES M Sbjct: 6 PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSIS-ESGM----- 59 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I G YT +A N G AS + EPP + + ++V GE Sbjct: 60 -LTIRGAAPEDSGNYTCLATNEVGTAS----QSVNVNYAEPPSISVVQQMVMVVAGEDAS 114 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKAENSEG 812 L Q G P P + W K + + P ++ D H T+ ++ + D G YT A N G Sbjct: 115 LECQASGTPSPIVKWQKGDLDLGTAPF-AEQDVHRGTLQIRGVQELDSGDYTCVASNIAG 173 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN-- 870 +SAV+ ++ P F +IT I L P PS+ W R + Sbjct: 174 --SSSAVVVLQV-----GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGR 226 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTF 930 I S + L I +V + D G Y C A N G ARVT+ + Sbjct: 227 PIFGKSSGHVGTSQLPSGALQIQSVWVD-DEGVYLCEAKNQFGSIKALARVTVTGLEPPL 285 Query: 931 VKHLQKSYETEEGKTVILECQTSHTVSTK---WYHNKKEI 967 + S T + + L C+ + W HN K++ Sbjct: 286 LVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQV 325 Score = 63.3 bits (147), Expect = 7e-08 Identities = 61/244 (25%), Positives = 96/244 (39%), Gaps = 19/244 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G PTFS+ P G +I L C P P + W + ++ P S + Sbjct: 184 GAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIW--RRQDGRPIFGKSSGHVGTSQL 241 Query: 691 YCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 L+I +V EG Y A N+ G S+ + ++ EPP +++ S+ + Sbjct: 242 PSGALQIQSVWVDDEGVYLCEAKNQFG--SIKALARVTVTGLEPPLLVQGAPSITTMIAQ 299 Query: 751 SVILSAQVV-GNPRPTITWCKNNKPVKA---LPTKSDGDTHSITILKPKKVKDEGVYTLK 806 + L +++ G P P W N K V+ + +SDG H + P +D G Y Sbjct: 300 PLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLH-VDRAVP---EDAGTYVCT 355 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 A N G A + + V P + A P T E I L P P+I+W Sbjct: 356 AVNVAGSANITVTVEVHAPPDIKAGP-------LHYTASEGTPISLSCEARGVPKPTISW 408 Query: 867 YRNN 870 + + Sbjct: 409 SKQH 412 Score = 61.7 bits (143), Expect = 2e-07 Identities = 59/218 (27%), Positives = 83/218 (38%), Gaps = 13/218 (5%) Query: 733 EPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL 792 E P V+ ++ G V +S G+P P + W N + S ++ +TI Sbjct: 4 EAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSISESGMLTI- 62 Query: 793 KPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKL 852 + +D G YT A N G A S + AEPP Q + V L Sbjct: 63 RGAAPEDSGNYTCLATNEVGTASQSVNVNY-------AEPPSISVVQQMVMVVAGEDASL 115 Query: 853 VARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 + + P P + W + + + + Q D L I V E+DSGDY CVASN A Sbjct: 116 ECQASGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGTLQIRGVQ-ELDSGDYTCVASNIA 172 Query: 913 GKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 G SS A V + V G + L C Sbjct: 173 GSSS--AVVVLQVGAAPTFSESPVDITASVGDNITLPC 208 Score = 58.4 bits (135), Expect = 2e-06 Identities = 81/393 (20%), Positives = 145/393 (36%), Gaps = 23/393 (5%) Query: 1288 PKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTI 1347 P +V + G++V + P P W + + H + SI S+S LTI Sbjct: 6 PSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSN--HHRMSI-SESGMLTI 62 Query: 1348 KKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENT 1407 + D+G Y N G A +NV + PS ++ + + + T Sbjct: 63 RGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASGT 122 Query: 1408 GNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASET 1467 S I+ + ++ T + +++ + I+ ++ S + A N S A Sbjct: 123 P-SPIVKWQKGDLDLGTAPFAE-QDVHRGTLQIRGVQELDSGDYTCVASNIAGSSSA--- 177 Query: 1468 TEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYR-DGKKLKTAK 1526 V+ +PT + +IT ++I L CI G P P + W R DG+ + Sbjct: 178 -----VVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPTPSLIWRRQDGRPIFGKS 232 Query: 1527 ATYENRXXXXXXXXXXXXX-----XXYKCIAFNDHGEVETSCVVGIQQ-KPVITISNEDI 1580 + + Y C A N G ++ V + +P + + Sbjct: 233 SGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPS 292 Query: 1581 KQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS 1640 L +++GIP PE IW NG ++ + + V R + Sbjct: 293 ITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVP---EDA 349 Query: 1641 SKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPV 1673 Y A N AG++++ VT++V+ P GP+ Sbjct: 350 GTYVCTAVNVAGSANITVTVEVHAPPDIKAGPL 382 Score = 56.8 bits (131), Expect = 6e-06 Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 5/208 (2%) Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXX 1537 +++P+V + + ++ ++C G P PKV W L + + Sbjct: 3 LEAPSVVVSPQTQSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSISESGMLTI 62 Query: 1538 XXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIE 1597 Y C+A N+ G S V + P I++ + + G++ + Sbjct: 63 RGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVV--AGEDASLECQAS 120 Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 G P P V W K L T ++I+ ++ S YT ASN AG+SS Sbjct: 121 GTPSPIVKWQKGDLDLGTAPFAEQDVHRGT--LQIRGVQELDSGDYTCVASNIAGSSSAV 178 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTI 1685 V L+V P+ E PV + +++T+ Sbjct: 179 VVLQVGAAPTFSESPVDITASVGDNITL 206 Score = 46.8 bits (106), Expect = 0.007 Identities = 68/363 (18%), Positives = 128/363 (35%), Gaps = 19/363 (5%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 L IR +D YTC+ + T V V PP I ++ + G D +L Sbjct: 60 LTIRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQA 119 Query: 1312 QAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADV 1371 P P +W + + D +L I+ V+ D+G Y N G + Sbjct: 120 SGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGTLQIRGVQELDSGDYTCVASNIAGSSSA 177 Query: 1372 EMNVTILDKPSPPGKP-NILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEI--DTTEW 1427 + + + P+ P +I +I + C T ++I+ + + I ++ Sbjct: 178 VVVLQVGAAPTFSESPVDITASVGDNITLPCIARGFPT--PSLIWRRQDGRPIFGKSSGH 235 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKP 1487 + + IQ++ + + A N+ A + T ++ P + + Sbjct: 236 VGTSQLPSGALQIQSVWVDDEGVYLCEAKNQFGSIKALAR------VTVTGLEPPLLVQG 289 Query: 1488 LKNITTEPNEDIELTC-IFGGVPQPKVTWYRDGKKLKTAKATY-ENRXXXXXXXXXXXXX 1545 +ITT + + L C + G+P P+ W +GK+++ + + Sbjct: 290 APSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGGRVFLRSDGSLHVDRAVPEDA 349 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y C A N G + V + P I + G ++ G+P P + Sbjct: 350 GTYVCTAVNVAGSANITVTVEVHAPP--DIKAGPLHYTASEGTPISLSCEARGVPKPTIS 407 Query: 1606 WYK 1608 W K Sbjct: 408 WSK 410 Score = 45.6 bits (103), Expect = 0.015 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 4/82 (4%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ V C G P P++ W + S +M + + T IR PED+G +TC Sbjct: 20 GAEVHISCSASGSPPPKVFWSHGNIFL--SNHHRMSISESGMLT--IRGAAPEDSGNYTC 75 Query: 584 VAKNAAGFASSTTELIVEAPLS 605 +A N G AS + + P S Sbjct: 76 LATNEVGTASQSVNVNYAEPPS 97 Score = 43.2 bits (97), Expect = 0.081 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G ECQ G P P + W + + + + D + TL IR V D+G +TC Sbjct: 110 GEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQ---DVHRGTLQIRGVQELDSGDYTC 166 Query: 584 VAKNAAGFASSTTELIVEA 602 VA N AG +S+ L V A Sbjct: 167 VASNIAGSSSAVVVLQVGA 185 Score = 42.7 bits (96), Expect = 0.11 Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 5/118 (4%) Query: 1569 QKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS 1628 + P + +S + Q +G E ++ G PPP+V W L N +I+ ++ Sbjct: 4 EAPSVVVSPQT--QSFSLGAEVHISCSASGSPPPKVFWSHGNIFLSNHHRMSIS---ESG 58 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 ++ I+ S YT A+N GT+S V + + PS ++ ++ E ++E Sbjct: 59 MLTIRGAAPEDSGNYTCLATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLE 116 Score = 42.7 bits (96), Expect = 0.11 Identities = 91/402 (22%), Positives = 145/402 (36%), Gaps = 36/402 (8%) Query: 943 GKTVILECQTSHTVSTK--WYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 G V + C S + K W H +S HR I E D G C+ Sbjct: 20 GAEVHISCSASGSPPPKVFWSHGNIFLSN-HHRMSISES--GMLTIRGAAPEDSGNYTCL 76 Query: 1001 VKDQ--ETSTMLVVKETIPEFIRKLQDFE-VKEKDVAILEVEINSETADVVWERDGEIIK 1057 ++ S + V P I +Q V + A LE + + + +V + G++ Sbjct: 77 ATNEVGTASQSVNVNYAEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDL-- 134 Query: 1058 PKKNKYDF-EKRGHIRKLYIRNTSVHDEGEYSCI---LRDESCTAEVTVVELPPEIITRL 1113 F E+ H L IR D G+Y+C+ + S V V P Sbjct: 135 -DLGTAPFAEQDVHRGTLQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAAPTFSESP 193 Query: 1114 QNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI--QFSNHIQLTIDGKKQKLKIYDC 1168 + + G+ T + +G +L+ +DG I + S H+ T L+I Sbjct: 194 VDITASVGDNITLPC-IARGFPTPSLIWRRQDGRPIFGKSSGHVG-TSQLPSGALQIQSV 251 Query: 1169 DLDDAGEYSCEV----GNSKCTAILTVE--EPS--INFTLRLPEFILVPANTDAYLTVEI 1220 +DD G Y CE G+ K A +TV EP + + I P N L I Sbjct: 252 WVDDEGVYLCEAKNQFGSIKALARVTVTGLEPPLLVQGAPSITTMIAQPLNLPCRLLDGI 311 Query: 1221 PDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLK 1280 P + W + + L SD +L + + +D Y C ++ + + Sbjct: 312 P--LPERIWTHNGKQVRVGGRVFLRSD---GSLHVDRAVPEDAGTYVCTAVNVAGSANIT 366 Query: 1281 VEV-VEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEW 1321 V V V PP I Y G+ ++L + + P+P W Sbjct: 367 VTVEVHAPPDIKAGPLHYTASEGTPISLSCEARGVPKPTISW 408 Score = 41.1 bits (92), Expect = 0.33 Identities = 78/362 (21%), Positives = 131/362 (36%), Gaps = 38/362 (10%) Query: 1047 VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---V 1103 V W G I ++ + G L IR + D G Y+C+ +E TA +V Sbjct: 37 VFWSH-GNIFLSNHHRMSISESG---MLTIRGAAPEDSGNYTCLATNEVGTASQSVNVNY 92 Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQK 1162 PP I Q V G A+ E + + +V+W K ++ + + D + Sbjct: 93 AEPPSISVVQQMVMVVAGEDASLECQASGTPSPIVKWQKGDLDLGTAPFAEQ--DVHRGT 150 Query: 1163 LKIYDCDLDDAGEYSCE----VGNSKCTAIL------TVEEPSINFTLRLPEFILVPANT 1212 L+I D+G+Y+C G+S +L T E ++ T + + I +P Sbjct: 151 LQIRGVQELDSGDYTCVASNIAGSSSAVVVLQVGAAPTFSESPVDITASVGDNITLPCIA 210 Query: 1213 DAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 + P +L + + + S + L I+ DD+ Y C + Sbjct: 211 RGF-----PTPSLIWRRQDGRPIFGKSSGHVGTSQLPSGALQIQSVWVDDEGVYLCEAKN 265 Query: 1273 ----AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL---LVDYQAFPQPNDEWIVNS 1325 K+ ++ V +E PP +V + L L+D P P W N Sbjct: 266 QFGSIKALARVTVTGLE-PPLLVQGAPSITTMIAQPLNLPCRLLD--GIPLPERIWTHNG 322 Query: 1326 KIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPG 1385 K ++ D SL + + DAG Y N G A++ + V + P Sbjct: 323 KQVRVGGRVFLRSD---GSLHVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAPPDIKA 379 Query: 1386 KP 1387 P Sbjct: 380 GP 381 Score = 39.9 bits (89), Expect = 0.75 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 5/95 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQV-EGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 P+ V+ T + C++ +G P P+ W ++ +++ D +L Sbjct: 284 PLLVQGAPSITTMIAQPLNLPCRLLDGIPLPERIWTHNGKQVRVGG--RVFLRSDG--SL 339 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + PEDAGT+ C A N AG A+ T + V AP Sbjct: 340 HVDRAVPEDAGTYVCTAVNVAGSANITVTVEVHAP 374 >UniRef50_Q08CM9 Cluster: Zgc:152904; n=12; Euteleostomi|Rep: Zgc:152904 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 809 Score = 93.9 bits (223), Expect = 4e-17 Identities = 130/664 (19%), Positives = 249/664 (37%), Gaps = 50/664 (7%) Query: 1215 YLTVEIPDETLDVTWYKKKSV-IEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDA 1273 + T E + + W+ + I E+ + ++ + L I ++ Y C DA Sbjct: 8 FFTCTAIGEPVSINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADA 67 Query: 1274 KSTTKLKVEVVEFPPKIV--DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKC 1331 K ++ V+E K+ + + ++G D ++ D + P P W ++ I Sbjct: 68 KGQSQEATVVLEIYQKLTFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYKNREITSE 127 Query: 1332 KHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILE 1391 +++ + + +L I KV D G Y+ +++ ++ PP +L Sbjct: 128 PNSRFQV-LPTNNLQILKVGKADEGAYRCEARVEA-RGEIDFRDIVVQVNVPP----VLS 181 Query: 1392 IDSSSINICWDEPENTGNSTI--------IYYVVEYQEIDTTEW--ISVKNITKTQTSIQ 1441 + S N D E+ + + + + + I+ +E ++ N K+ +++ Sbjct: 182 VPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVK 241 Query: 1442 NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIEL 1501 N+K + A N+ + +SE+ + KV + I L+N+T + Sbjct: 242 NIKQTDGGPYMCRASNK---AGSSESQLFLKVFVQPHITQ------LRNVTAVEGSAAMI 292 Query: 1502 TCIFGGVPQPKVTWYR--------DGKKLKTAKATYENRXXXXXXXXXXXXXX---XYKC 1550 +C G P P+++W R DG+K K + R + C Sbjct: 293 SCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDC 352 Query: 1551 IAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG 1610 A + G + S + I+ P +N+ I + G+ ++ ++ P ++W + Sbjct: 353 EALSRIGGHQKSMFLDIEYAPKFQ-TNQSIFYSWE-GNPVNISCEVKSNPAATMLWRRER 410 Query: 1611 NKLENDKEYNIT--TKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + + NI + + S++ + + +Y A N G E L D PS Sbjct: 411 FTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSS 470 Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P V M +S+ T+ + P GG+ ++ Y I + + + + A + Sbjct: 471 PYS-VRMTAVSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEWRSARTHGVQTAVVL 529 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 L N Y RV A N G E +E + PS Y Sbjct: 530 TSLEPNTTYEVRVSAVNGKGQGEFSHTESFQ-TLPIREPSPPTVHGQRGV---GKAYRLG 585 Query: 1789 FPSEKNGGSPIIDYKVEIK-QEGKKWKXXXX-XXXXXARIQKLSINTTYQFRIYARNEIG 1846 + +GG PI++Y ++ K + ++W A +Q L NT Y I ARN G Sbjct: 586 LVKQDDGGMPIVEYILKYKTDKEEQWMTKLVPGMNDFALLQPLQWNTRYNVEITARNVKG 645 Query: 1847 TSLP 1850 S P Sbjct: 646 LSEP 649 Score = 67.3 bits (157), Expect = 4e-09 Identities = 84/353 (23%), Positives = 143/353 (40%), Gaps = 42/353 (11%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 TF + Q +G D + C +++ P P ++W +K EI + N + + + Sbjct: 85 TFREVKTPQEFRQGDDAEVVCDVISSPVPAVSWFYKNREITSEPNSRFQV-----LPTNN 139 Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASL-PIVLKIKTGEKEPPQVIEPLKSM--IVRQGE 750 L+I V K EG Y A V GE IV+++ PP + P +S E Sbjct: 140 LQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNV----PPVLSVPQQSFNATADYQE 195 Query: 751 SVILSAQVVGNPRPTITWCKNNKPVK-----ALPTKSDGDTHSITILKPKKVKDEGVYTL 805 SV + G+P P +TW ++ L T + G + ++T+ K K D G Y Sbjct: 196 SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKS-TLTV-KNIKQTDGGPYMC 253 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A N G +E+ + V +P I + + +T E + P+P I+ Sbjct: 254 RASNKAGSSESQLFLKV------FVQP--HITQLRNVTAVEGSAAMISCTAEGEPLPEIS 305 Query: 866 WYR--------NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSH 917 W R + E + G+++ L I+ V D G + C A + G H Sbjct: 306 WRRASDGHSFTDGEKSKDGRVEVRGRHGKSM-LTISGVQLS-DWGRFDCEALSRIG--GH 361 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT-SHTVSTK-WYHNKKEIS 968 + +D+E + Q + + EG V + C+ S+ +T W + IS Sbjct: 362 QKSMFLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFTIS 414 Score = 61.3 bits (142), Expect = 3e-07 Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFK-TVKGKSWTKIVTVGGSVHE 1924 PS P + ++ + R T+ + +P+S+GG PI+ YII ++ T + W T G Sbjct: 468 PSSPYSVRMTAVSQRMATVSFMKPDSHGGVPISFYIINYRDTSSAQEWRSARTHGVQT-A 526 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVM 1984 + +++ R+SA N G + ++S + PSPPT + R VG + Sbjct: 527 VVLTSLEPNTTYEVRVSAVNGKGQGEFSHTESFQ-TLPIREPSPPTVHGQ-RGVGKAYRL 584 Query: 1985 TSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYAR 2044 + DGG P++ Y + + + WM +N ++ L N Y + I AR Sbjct: 585 GL--VKQDDGGMPIVEYILKYKTDKEEQWMTKLVPGMNDFAL-LQPLQWNTRYNVEITAR 641 Query: 2045 NEIGLSEP 2052 N GLSEP Sbjct: 642 NVKGLSEP 649 Score = 60.1 bits (139), Expect = 7e-07 Identities = 58/282 (20%), Positives = 117/282 (41%), Gaps = 15/282 (5%) Query: 1137 VRWFKDGSEIQFSNH-IQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK-----CTAILT 1190 + WF E SN + + +G + +L IY+ +++AG Y C+ ++K T +L Sbjct: 20 INWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIENAGIYRCQAADAKGQSQEATVVLE 79 Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 + + ++ P+ + + V I V+W+ K I +E + + Sbjct: 80 IYQKLTFREVKTPQEFRQGDDAEVVCDV-ISSPVPAVSWFYKNREIT-SEPNSRFQVLPT 137 Query: 1251 RTLIIRKCTEDDQCEYTC-VLLDAKSTTKLKVEVVEF--PPKIVDYEREYRIKRG--SDV 1305 L I K + D+ Y C ++A+ + VV+ PP + ++ + V Sbjct: 138 NNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQSFNATADYQESV 197 Query: 1306 TLLVDYQAFPQPNDEWIVNSKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKLRLEN 1364 T P P W I+ + + +++ ++LT+K ++ TD G Y R N Sbjct: 198 TFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRASN 257 Query: 1365 NCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI-CWDEPE 1405 G ++ ++ + + +P N+ ++ S+ I C E E Sbjct: 258 KAGSSESQLFLKVFVQPHITQLRNVTAVEGSAAMISCTAEGE 299 Score = 54.4 bits (125), Expect = 3e-05 Identities = 76/340 (22%), Positives = 141/340 (41%), Gaps = 28/340 (8%) Query: 863 SITWYR-NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 SI W+ E I +E + + +G L I N E ++G Y+C A+++ G+S V Sbjct: 19 SINWFSPQGERIISNERVIVHTEGVRSRLTIYNAIIE-NAGIYRCQAADAKGQSQEATVV 77 Query: 922 TIDVEKVTF--VKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979 +K+TF VK Q+ + ++ + V+ + +S + W++ +EI+ + Q Sbjct: 78 LEIYQKLTFREVKTPQEFRQGDDAE-VVCDVISSPVPAVSWFYKNREITS-EPNSRFQVL 135 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETSTM----LVVKETIPEFIR-KLQDFEVK---EK 1031 D G +C + + + +VV+ +P + Q F ++ Sbjct: 136 PTNNLQILKVGKADEGAYRCEARVEARGEIDFRDIVVQVNVPPVLSVPQQSFNATADYQE 195 Query: 1032 DVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCIL 1091 V V S V W G I+ + G L ++N D G Y C Sbjct: 196 SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRA 255 Query: 1092 RDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFK--DG- 1143 +++ ++E + V + P IT+L+N +G+ A +G+ L + W + DG Sbjct: 256 SNKAGSSESQLFLKVFVQPH-ITQLRNVTAVEGSAAMISC-TAEGEPLPEISWRRASDGH 313 Query: 1144 --SEIQFSNHIQLTIDGK--KQKLKIYDCDLDDAGEYSCE 1179 ++ + S ++ + G+ K L I L D G + CE Sbjct: 314 SFTDGEKSKDGRVEVRGRHGKSMLTISGVQLSDWGRFDCE 353 Score = 50.0 bits (114), Expect = 7e-04 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +V F C G P PQ+TW+ + I+ S+ + + + +TL ++ + D G + C A Sbjct: 196 SVTFTCVTSGSPDPQVTWYWKGHAIEHSEQYVLNTMNGGKSTLTVKNIKQTDGGPYMCRA 255 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEM 611 N AG SS ++L ++ + H +++ Sbjct: 256 SNKAG--SSESQLFLKVFVQPHITQL 279 Score = 38.7 bits (86), Expect = 1.7 Identities = 31/149 (20%), Positives = 54/149 (36%), Gaps = 2/149 (1%) Query: 490 EKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAI 549 E + ++ +K + AP F ++ +G+ V C+V+ P + W R+ Sbjct: 353 EALSRIGGHQKSMFLDIEYAPKFQTNQSIFYSWEGNPVNISCEVKSNPAATMLWRRERFT 412 Query: 550 IKPSQDFQM-YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELI-VEAPLSDH 607 I + + D + L + V D G + C A+N G L + P S + Sbjct: 413 ISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIGARYQEFILAQADVPSSPY 472 Query: 608 GSEMTVXXXXXXXXXXXXADILEGIPPTF 636 MT D G+P +F Sbjct: 473 SVRMTAVSQRMATVSFMKPDSHGGVPISF 501 Score = 37.1 bits (82), Expect = 5.3 Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 13/174 (7%) Query: 647 EGSDILLECRLVAIPEPDIAW--LFKGEEIVPDENISVA-IESDMHMYCSVLKITNVKKF 703 EGS ++ C P P+I+W G E +E S+L I+ V+ Sbjct: 286 EGSAAMISCTAEGEPLPEISWRRASDGHSFTDGEKSKDGRVEVRGRHGKSMLTISGVQLS 345 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVR-QGESVILSAQVVGNP 762 G + A++R G + L I+ K + +S+ +G V +S +V NP Sbjct: 346 DWGRFDCEALSRIGGHQKSMFLDIEYAPK-----FQTNQSIFYSWEGNPVNISCEVKSNP 400 Query: 763 RPTITWCKNNKPVKALPTKS----DGDTHSITILKPKKVKDEGVYTLKAENSEG 812 T+ W + + + T + D S+ + P +D G Y A N+ G Sbjct: 401 AATMLWRRERFTISSQGTSNIRIHSTDGRSLLEVTPVSDRDFGRYNCTARNNIG 454 >UniRef50_Q9HCK4 Cluster: Roundabout homolog 2 precursor; n=45; Euteleostomi|Rep: Roundabout homolog 2 precursor - Homo sapiens (Human) Length = 1378 Score = 93.9 bits (223), Expect = 4e-17 Identities = 82/312 (26%), Positives = 130/312 (41%), Gaps = 25/312 (8%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 PTF ++P Q V E + C++ P+P + W K + +P I+ D Sbjct: 225 PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWK-KDDADLPRGRYD--IKDDY----- 276 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+I EGTY +A NR G+ L ++ PPQ + + IV QG +V Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVT 332 Query: 754 LSAQVVGNPRPTITWCKN--------NKPVKALPTKSDGDTHSITILKPKKVKDEGVYTL 805 + GNP+P + W K N+P + S T +TI ++ D G Y Sbjct: 333 FPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQR-SDAGYYIC 391 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A G A + V + + PP+ + T+ GT L + T +P+P I+ Sbjct: 392 QALTVAGSILAKAQLEVTDVLTDRP-PPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 450 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W + P E L I N+ D+G Y CVA++S+G++S A + + Sbjct: 451 WLKEG-FTFPGRDPRATIQ-EQGTLQIKNLRIS-DTGTYTCVATSSSGETSWSAVLDVTE 507 Query: 926 EKVTFVKHLQKS 937 T K+ S Sbjct: 508 SGATISKNYDLS 519 Score = 81.0 bits (191), Expect = 3e-13 Identities = 88/418 (21%), Positives = 161/418 (38%), Gaps = 29/418 (6%) Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPS--IDSKS 1342 +FPP+IV++ + + +G TL + P P EW + + ++ K S + S Sbjct: 28 DFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPS 87 Query: 1343 ASLTIKKV-----ENTDAGIYKLRLENNCGHA---DVEMNVTILDKPSPPGKPNILEIDS 1394 SL ++ D G Y N G A + + V +L +++ Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAG 147 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY 1454 + P TI + + + D E IS++ + I N + + + + Sbjct: 148 EPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRG---GKLMISNTRKSDAGMYTCV 204 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPT-VEKPLKNITTEPNEDIELTCIFGGVPQPKV 1513 N V D S+ E T + PT + +P+ + E E +E C G PQP V Sbjct: 205 GTNMVGERD-SDPAEL------TVFERPTFLRRPINQVVLE-EEAVEFRCQVQGDPQPTV 256 Query: 1514 TWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVI 1573 W +D L + ++ Y CIA N G++E S + ++ P Sbjct: 257 RWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQF 316 Query: 1574 TISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNK---LENDKEY--NITTKEKTS 1628 + D Q G +G P P V W K G++ N + + + T Sbjct: 317 VVRPRD--QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTG 374 Query: 1629 VIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + I ++RS + Y +A AG+ + L+V D + P+I++ + +++ ++ Sbjct: 375 DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432 Score = 79.0 bits (186), Expect = 1e-12 Identities = 82/334 (24%), Positives = 132/334 (39%), Gaps = 34/334 (10%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDE----NISVAIE 685 E PP + P V +G L C+ P P I W GE + D+ + + + Sbjct: 27 EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLP 86 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGE-----ASLPIVLKIKTGEKEPPQVIEP 740 S + ++ K EG+Y VA N GE ASL + L + P V Sbjct: 87 SGSLFFLRIVHGRRSKP-DEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDV--- 142 Query: 741 LKSMIVRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKD 799 +V GE IL Q G+P PTI W K+ + + + I +K D Sbjct: 143 ----VVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRK-SD 197 Query: 800 EGVYTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 G+YT N G ++ A +TV E P F+ R V E+ ++ +V Sbjct: 198 AGMYTCVGTNMVGERDSDPAELTV-------FERPTFLRRPINQVVLEEEAVEFRCQVQG 250 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 +P P++ W +++ ++ +D ++ + D G Y C+A N GK Sbjct: 251 DPQPTVRWKKDD-----ADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEAS 305 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 A +T+ V+ + +G+TV C+T Sbjct: 306 ATLTVRAPPQFVVR--PRDQIVAQGRTVTFPCET 337 Score = 72.1 bits (169), Expect = 2e-10 Identities = 114/495 (23%), Positives = 195/495 (39%), Gaps = 46/495 (9%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790 E PP+++E +IV +GE L+ + G P PTI W K+ + V+ K D +H + Sbjct: 27 EDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVET--DKDDPRSHRML 84 Query: 791 ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENA--EPPLFINRFQ----EITV 844 + V+ +++ EG A + E NA E L + F+ ++ V Sbjct: 85 LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV 144 Query: 845 KEKGTIKLVARVTR-NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 L + R +P P+I W ++ I E + +L+I+N + D+G Sbjct: 145 AAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKE---ERISIRGGKLMISNT-RKSDAGM 200 Query: 904 YKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYH 962 Y CV +N G + S A +T+ E+ TF++ EE + V CQ Sbjct: 201 YTCVGTNMVGERDSDPAELTV-FERPTFLRRPINQVVLEE-EAVEFRCQVQGDPQPTVRW 258 Query: 963 NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVVKETIPE 1018 K + R I++ D G CI +++ E S L V+ P+ Sbjct: 259 KKDDADLPRGRYDIKD--DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-PQ 315 Query: 1019 FIRKLQDFEVKEKDVAILEVEINSETADVV-WERDG--EIIKPKKNKYDFEK--RGHIRK 1073 F+ + +D V + E V W+++G ++ P + + + Sbjct: 316 FVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGD 375 Query: 1074 LYIRNTSVHDEGEYSC----ILRDESCTAEVTVVEL-----PPEIITRLQNQKVNKGNKA 1124 L I N D G Y C + A++ V ++ PP I+ NQ + A Sbjct: 376 LTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTA 435 Query: 1125 TFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC---- 1178 + + T GD L + W K+G F ++ L+I + + D G Y+C Sbjct: 436 LLKCKAT-GDPLPVISWLKEG--FTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 492 Query: 1179 EVGNSKCTAILTVEE 1193 G + +A+L V E Sbjct: 493 SSGETSWSAVLDVTE 507 Score = 66.9 bits (156), Expect = 6e-09 Identities = 45/195 (23%), Positives = 80/195 (41%), Gaps = 3/195 (1%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY- 691 PP F +P+ Q V +G + C P+P + W +G + + N S + Sbjct: 313 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIK--TGEKEPPQVIEPLKSMIVRQG 749 L ITN+++ G Y A+ G L++ ++ PP +++ + + Sbjct: 373 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + +L + G+P P I+W K ++ +K ++ D G YT A + Sbjct: 433 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATS 492 Query: 810 SEGIAETSAVITVEE 824 S G SAV+ V E Sbjct: 493 SSGETSWSAVLDVTE 507 Score = 60.5 bits (140), Expect = 5e-07 Identities = 103/477 (21%), Positives = 181/477 (37%), Gaps = 57/477 (11%) Query: 1315 PQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVE-M 1373 P+P W K+ K + SI + L I +DAG+Y N G D + Sbjct: 161 PEPTIYW-KKDKVRIDDKEERISI--RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPA 217 Query: 1374 NVTILDKPSPPGKP-NILEIDSSSINI-CWDEPENTGNSTIIYYVVEYQEIDTTEWISVK 1431 +T+ ++P+ +P N + ++ ++ C + + T+ + + D + + Sbjct: 218 ELTVFERPTFLRRPINQVVLEEEAVEFRC--QVQGDPQPTVRW------KKDDADLPRGR 269 Query: 1432 NITKTQTSIQNLKTNSSYR--FRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLK 1489 K +++ KT S+ + A N V +AS T + V +P Sbjct: 270 YDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLT-------VRAPPQFVVRPRD 322 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKK---------LKTAKATYENRXXXXXXXX 1540 I + + C G PQP V W ++G + ++ + Sbjct: 323 QIVAQ-GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 381 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQ----KPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C A G + + + +P I Q V L+ Sbjct: 382 QRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKA 441 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSV 1656 G P P + W K G ++ T +E+ ++IK L+ S + YT A++++G +S Sbjct: 442 TGDPLPVISWLKEGFTFPG-RDPRATIQEQ-GTLQIKNLRISDTGTYTCVATSSSGETSW 499 Query: 1657 EVTLKVY-------------DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAI 1703 L V D P P P + ++++ SVT+ W+P G L + Y I Sbjct: 500 SAVLDVTESGATISKNYDLSDLPGPPSKPQVT-DVTKNSVTLSWQPGTP-GTLPASAYII 557 Query: 1704 EKHEPD-NNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPI 1758 E +N W VA+ + Y ++ L N Y+F V A NP G S+ + S+P+ Sbjct: 558 EAFSQSVSNSWQTVANHVKTT-LYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPV 613 Score = 58.4 bits (135), Expect = 2e-06 Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 34/222 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQ--MYYDDDNV 565 P FV + R + G TV F C+ +G P+P + W ++ + ++ P+Q Q Sbjct: 314 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 373 Query: 566 ATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXX 625 L I + DAG + C A AG + +L V L+D Sbjct: 374 GDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP----------------- 416 Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 PP + P Q + LL+C+ P P I+WL +G P + I+ Sbjct: 417 -------PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTF-PGRDPRATIQ 468 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKI 727 L+I N++ GTYT VA + GE S VL + Sbjct: 469 EQ-----GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505 Score = 55.2 bits (127), Expect = 2e-05 Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 14/110 (12%) Query: 494 KLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS 553 +L VFE+PT + + + +E+ V+F CQV+G P+P + W + A + Sbjct: 218 ELTVFERPTFLRRPINQVVLEE---------EAVEFRCQVQGDPQPTVRWKKDDADLPRG 268 Query: 554 QDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 + YD + TL I++ D GT+ C+A+N G ++ L V AP Sbjct: 269 R-----YDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP 313 Score = 54.0 bits (124), Expect = 4e-05 Identities = 96/418 (22%), Positives = 162/418 (38%), Gaps = 43/418 (10%) Query: 1017 PEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKR----GHI 1071 P + D V + + L + T + W +DGE ++ K+ + G + Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90 Query: 1072 RKLYIRN--TSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRLQNQKVNKGNKA 1124 L I + S DEG Y C+ R+ S A + V L + + V G A Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 150 Query: 1125 TFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 E + +G + + W KD I +++I G K L I + DAG Y+C N Sbjct: 151 ILECQPPRGHPEPTIYWKKDKVRIDDKEE-RISIRGGK--LMISNTRKSDAGMYTCVGTN 207 Query: 1183 -----SKCTAILTV-EEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVI 1236 A LTV E P+ LR P +V ++ + +KK Sbjct: 208 MVGERDSDPAELTVFERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDAD 264 Query: 1237 EDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDYER 1295 ++ + D TL I+K D+ Y C+ + + + V PP+ V R Sbjct: 265 LPRGRYDIKDDY---TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 321 Query: 1296 EYRIKRGSDVTLLVDYQAFPQPNDEWIV--NSKIIKKCKHTKPSID---SKSASLTIKKV 1350 + + +G VT + + PQP W + ++ + +P+ S + LTI + Sbjct: 322 DQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 381 Query: 1351 ENTDAGIYKLRLENNCG----HADVEMNVTILDKPSP---PGKPN-ILEIDSSSINIC 1400 + +DAG Y + G A +E+ + D+P P G N L +D +++ C Sbjct: 382 QRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKC 439 Score = 41.1 bits (92), Expect = 0.33 Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 15/118 (12%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVH 1923 PPS+P+ V++ T SVTL W +P + G P + YIIE F SW TV V Sbjct: 524 PPSKPQ---VTDVTKNSVTLSW-QPGTPGTLPASAYIIEAFSQSVSNSWQ---TVANHVK 576 Query: 1924 E--HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHATVPSPPTAPLEIRMV 1978 + + ++ +F + A N G+S P+ S VR + SPP ++ R V Sbjct: 577 TTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQD----ISPPAQGVDHRQV 630 >UniRef50_Q92823 Cluster: Neuronal cell adhesion molecule precursor; n=22; Euteleostomi|Rep: Neuronal cell adhesion molecule precursor - Homo sapiens (Human) Length = 1304 Score = 93.9 bits (223), Expect = 4e-17 Identities = 114/478 (23%), Positives = 194/478 (40%), Gaps = 48/478 (10%) Query: 507 SMAPIFV-EKLRPKHTPDGSTVQFECQVE-GYPRPQITWFRQTAIIKP-SQDFQMYYDDD 563 S +P++ EKL P G ++ C+ G P P I W + P S+ + D Sbjct: 142 SRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGD 201 Query: 564 NVATLVIREVFPEDAGT-FTCVAK-NAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXX 621 L V PED + C A+ N + V+ D ++ T+ Sbjct: 202 ----LYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELND-TIAANLSDTE 256 Query: 622 XXXXADILEGIPPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDE 678 E PPTF + + A +E G+ + LEC +P P I W K + ++P + Sbjct: 257 FYGAKSSRER-PPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWA-KEDGMLP-K 313 Query: 679 NISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI 738 N +V + L+I +V + G Y +A N G I +++K P I Sbjct: 314 NRTVYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAA----PYWI 364 Query: 739 EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP----TKSDGDTHSITILKP 794 +++++ GE L + GNP+P I+W N P++ P K DGDT I Sbjct: 365 TAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT---IIFSN 421 Query: 795 KKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLV 853 + + VY A N G +A + V AEPP + + V L Sbjct: 422 VQERSSAVYQCNASNEYGYLLANAFVNV------LAEPPRILTPANTLYQVIANRPALLD 475 Query: 854 ARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 +P+P+I W++ + + E I + +E+ + DS +G Y CVA N G Sbjct: 476 CAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDS---TGTYTCVARNKLG 532 Query: 914 KSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH----TVSTKWYHNKKEI 967 + + V ++++ T++ + + G V EC+ H +++ W + +E+ Sbjct: 533 MAKN--EVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNREL 588 Score = 89.4 bits (212), Expect = 9e-16 Identities = 117/529 (22%), Positives = 207/529 (39%), Gaps = 53/529 (10%) Query: 1489 KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR---XXXXXXXXXXXXX 1545 +N+ P ED L C G P+P+++W +G ++ A + Sbjct: 368 QNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSS 427 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C A N++G + + V + +P ++ + + L+ G P P + Sbjct: 428 AVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIE 487 Query: 1606 WYK--NGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 W+K G+ L D I + + I ++ + YT A N G + EV L++ Sbjct: 488 WFKGAKGSALHED----IYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 543 Query: 1664 DKP---SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE--PDNNRWIKVAD 1718 D +PE V+ R V+ E K D L LT ++ + P + R+ Sbjct: 544 DPTWIVKQPEYAVVQR---GSMVSFECKVK-HDHTLSLTVLWLKDNRELPSDERF----T 595 Query: 1719 VDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT-----ALDVPSXXXXX 1773 VD+D + ++++ + +A + A +V T DVP+ Sbjct: 596 VDKD--HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDL 653 Query: 1774 XXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKK---WKXXXXXXXXXARIQ-KL 1829 +D +SV ++W P + N SPI + +E + K W Q KL Sbjct: 654 ELTDQLD-KSVQLSWTPGDDN-NSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKL 711 Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP 1889 S Y FR+ A N IG SLP + ++ + K P P S ++ + W +P Sbjct: 712 SPYVNYSFRVMAVNSIGKSLPSEASEQY-LTKASEPDKNPTAVEGLGSEPDNLVITW-KP 769 Query: 1890 ----ESNGGSPITNYIIEFKTVKG-KSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAEN 1944 ESNG P Y + ++ G WT +V +V ++ + + ++ A N Sbjct: 770 LNGFESNG--PGLQYKVSWRQKDGDDEWTSVVV--ANVSKYIVSGTPTFVPYLIKVQALN 825 Query: 1945 TVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWD 1993 +G + + + H+ P AP +R+ N+V ++ WD Sbjct: 826 DMGFA----PEPAVVMGHSGEDLPMVAPGNVRV---NVVNSTLAEVHWD 867 Score = 84.6 bits (200), Expect = 3e-14 Identities = 135/647 (20%), Positives = 259/647 (40%), Gaps = 74/647 (11%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT +++ PK +D +I+++C P P +W G D++ V ++ Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + + EG Y A N G A S IV++ + P E L+ + ++ G+ Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKEKLEPITLQSGQ 161 Query: 751 SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803 S++L + +G P P I W N+ + LP +GD + +L P+ +++ + Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 218 Query: 804 TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843 + +++ I + + VI+V+E TE PP F+ + Sbjct: 219 YARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNAS 278 Query: 844 VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 KE +G + + + P P I W + + ++ + T+ +NF+ + ++++ SE D Sbjct: 279 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFE-KTLQIIHV---SEAD 334 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960 SG+Y+C+A N+ G H V + E T+I + W Sbjct: 335 SGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394 Query: 961 YHN--KKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKE 1014 N EI+ D I +G V +C ++ + + V Sbjct: 395 LTNGVPIEIAPDDPSRKI-DGDTIIFSNVQERSS--AVYQCNASNEYGYLLANAFVNVLA 451 Query: 1015 TIPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIR 1072 P + ++V A+L+ S + W + + ++ Y + G Sbjct: 452 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENG--- 508 Query: 1073 KLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIE 1129 L I G Y+C+ R++ A+ V ++ P I+ + + V +G+ +FE + Sbjct: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568 Query: 1130 LTKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNS--- 1183 + L V W KD E+ + T+D K L + D DD+G Y+C + Sbjct: 569 VKHDHTLSLTVLWLKDNRELPSDE--RFTVD--KDHLVVADVSDDDSGTYTCVANTTLDS 624 Query: 1184 -KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 +A+L+V P+ P + + D LT ++ D+++ ++W Sbjct: 625 VSASAVLSVVAPT---PTPAPVYDVPNPPFDLELTDQL-DKSVQLSW 667 Score = 76.6 bits (180), Expect = 7e-12 Identities = 165/773 (21%), Positives = 294/773 (38%), Gaps = 84/773 (10%) Query: 1044 TADVVWERDGEIIKPKKNKY-DFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV 1102 T + W ++ ++ + Y +FEK L I + S D G Y CI ++ T+ Sbjct: 299 TPIIYWAKEDGMLPKNRTVYKNFEKT-----LQIIHVSEADSGNYQCIAKNALGAIHHTI 353 Query: 1103 ---VELPPEIITRLQNQKVNKGNKATFEIELTKGDALVR--WFKDGSEIQFS-NHIQLTI 1156 V+ P IT QN ++ G T I G+ R W +G I+ + + I Sbjct: 354 SVRVKAAPYWITAPQNLVLSPGEDGTL-ICRANGNPKPRISWLTNGVPIEIAPDDPSRKI 412 Query: 1157 DGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYL 1216 DG + + + Y C N + +N L P IL PANT Y Sbjct: 413 DG--DTIIFSNVQERSSAVYQCNASNEYGYLLANA---FVN-VLAEPPRILTPANT-LYQ 465 Query: 1217 TVEIPDETLDVTWYKKK-SVIE---DTEKFTLISDV----KKRTLIIRKCTEDDQCEYTC 1268 + LD ++ IE + L D+ + TL I +D YTC Sbjct: 466 VIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTC 525 Query: 1269 VLLDAKSTTKLKVEVVEFPPKIVDYEREYRI-KRGSDVTLLVDYQAFPQPNDEWIVNSKI 1327 V + K +V + P + + EY + +RGS +V ++ + +D + + + Sbjct: 526 VARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGS----MVSFECKVK-HDHTLSLTVL 580 Query: 1328 IKKCKHTKPSIDSKSAS---LTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL------ 1378 K PS + + L + V + D+G Y ++++ Sbjct: 581 WLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTP 640 Query: 1379 ----DKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--WISVKN 1432 D P+PP + + S+ + W P + NS I +++EY++ W Sbjct: 641 APVYDVPNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTE 699 Query: 1433 ITKTQTSIQ-NLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKN- 1490 ++ TQT+ Q L +Y FR AVN + S SE +E Y ++PT + L + Sbjct: 700 VSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSE 759 Query: 1491 -----ITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545 IT +P E G Q KV+W + + N Sbjct: 760 PDNLVITWKPLNGFESN---GPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVP 816 Query: 1546 XXYKCIAFNDHG-EVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 K A ND G E + V+G + + ++ +++ V + L + +P + Sbjct: 817 YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV--NVVNSTLAEVHWDPVPLKSI 874 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSV---IRIKELKRSHS--------SKYTIEASNTAGT 1653 + G ++ K + + + + + I + ++H S YT+ G Sbjct: 875 RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934 Query: 1654 SSVEVTL-KVYDKP-SKPEGPVIMREI--SRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 + +V++ P P P ++ + + +S+T+EW PP G+ LT+Y + K++P Sbjct: 935 GEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTL-KYQPI 992 Query: 1710 NNRWIKVADVDRDVET----YCIQKLNENCEYMFRVIAQNPVGFSEALESEPI 1758 N+ VD + + ++ LN + Y F AQ G + E + Sbjct: 993 NSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAV 1045 Score = 65.3 bits (152), Expect = 2e-08 Identities = 52/191 (27%), Positives = 87/191 (45%), Gaps = 8/191 (4%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923 P+ P + +++ +SV L WT P + SPIT +IIE++ K W V G+ Sbjct: 647 PNPPFDLELTDQLDKSVQLSWT-PGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQT 705 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 ++ + FR+ A N++G SLP+E+ L K + PTA + N+V Sbjct: 706 TAQLK-LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLV 764 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 +T ++ P L Y ++ R W V V N K+ + Y+I++ Sbjct: 765 ITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSV--VVANVSKYIVSGTPTFVPYLIKVQ 822 Query: 2043 ARNEIGLS-EP 2052 A N++G + EP Sbjct: 823 ALNDMGFAPEP 833 Score = 57.6 bits (133), Expect = 4e-06 Identities = 63/290 (21%), Positives = 114/290 (39%), Gaps = 12/290 (4%) Query: 1383 PPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQN 1442 PP P I +D+S + E + G + +Y+ E ++I TQT IQ Sbjct: 174 PP--PIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQ 230 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDI 1499 + S +N+ ++ S+T E+Y K ++ + PT P N + + + Sbjct: 231 KQPISVKVISVDELNDTIAANLSDT-EFYGA-KSSRERPPTFLTPEGNASNKEELRGNVL 288 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGE 1558 L CI G+P P + W ++ L + Y+N Y+CIA N G Sbjct: 289 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGA 348 Query: 1559 VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + + V ++ P + +++ G++ + G P P + W NG +E + Sbjct: 349 IHHTISVRVKAAPYWITAPQNLVL--SPGEDGTLICRANGNPKPRISWLTNGVPIEIAPD 406 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 + + K I ++ S+ Y ASN G + V +P + Sbjct: 407 -DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPR 455 Score = 56.4 bits (130), Expect = 8e-06 Identities = 171/816 (20%), Positives = 308/816 (37%), Gaps = 97/816 (11%) Query: 721 LPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA-- 777 +P+ K+ +PP + + K I+ E++++ + G P P+ +W +N Sbjct: 32 VPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDK 91 Query: 778 --LPTKSDGD-THSITILKPKKVKD-EGVYTLKAENSEGIAETSAVIT--VEEP--TEEN 829 L T G T I I+ K + EGVY A N G A ++ ++ P T+E Sbjct: 92 DPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEK 151 Query: 830 AEP---------------------PLFI---NRFQEITVKEKGTIKLVARVT-RNPVPSI 864 EP P+ N FQ + E+ + L + N +P Sbjct: 152 LEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPED 211 Query: 865 TWYRNNEIISPSETITQNFDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 T R + I TQ + I + + +VD D+ +A+N + +GA+ + Sbjct: 212 T--REDYICYARFNHTQTIQQKQPISVKVISVDELNDT-----IAANLSDTEFYGAKSSR 264 Query: 924 DVEKVTFVKHLQKSYETEE--GKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRX 981 + TF+ + EE G + LEC + + T + KE + + + Sbjct: 265 E-RPPTFLTPEGNASNKEELRGNVLSLEC-IAEGLPTPIIYWAKEDGMLPKNRTVYKNFE 322 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETS---TMLVVKETIPEFIRKLQDFEVKEKDVAILEV 1038 D G +CI K+ + T+ V + P +I Q+ + + L Sbjct: 323 KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC 382 Query: 1039 EINSETAD-VVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDES-- 1095 N + W +G I+ + D ++ + N Y C +E Sbjct: 383 RANGNPKPRISWLTNGVPIEIAPD--DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGY 440 Query: 1096 --CTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDAL--VRWFKDGSEIQFSNH 1151 A V V+ PP I+T N+ G L + WFK H Sbjct: 441 LLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSAL--H 498 Query: 1152 IQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEPSINFTLRLPEFIL 1207 + + + L+I D G Y+C ++G +K L +++P+ + ++ PE+ + Sbjct: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPT--WIVKQPEYAV 556 Query: 1208 VPANTDAYLTVEIP-DETLDVT--WYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQC 1264 V + ++ D TL +T W K + E+FT V K L++ ++DD Sbjct: 557 VQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFT----VDKDHLVVADVSDDDSG 612 Query: 1265 EYTCV---LLDAKSTTKLKVEVVEFPPKIVDYE---REYRIKRGSDVTLLVDYQAFPQPN 1318 YTCV LD+ S + + V P Y+ + ++ + V P + Sbjct: 613 TYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672 Query: 1319 DEWIVNSKIIK-KCKHTKPSI----DSKSASLTIKKVENTDAGIYKLRL--ENNCGHA-D 1370 + + II+ + KP + S + T +++ + Y R+ N+ G + Sbjct: 673 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 732 Query: 1371 VEMNVTILDKPSPPGK-PNILE---IDSSSINICWDEPEN--TGNSTIIYYVVEYQEID- 1423 E + L K S P K P +E + ++ I W +P N N + Y V +++ D Sbjct: 733 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITW-KPLNGFESNGPGLQYKVSWRQKDG 791 Query: 1424 TTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 EW SV ++ + T Y + A+N++ Sbjct: 792 DDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDM 827 Score = 41.9 bits (94), Expect = 0.19 Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 7/82 (8%) Query: 524 GSTVQFECQVEGYPRPQIT--WFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 GS V FEC+V+ +T W + + + F + D D+ LV+ +V +D+GT+ Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTV--DKDH---LVVADVSDDDSGTY 614 Query: 582 TCVAKNAAGFASSTTELIVEAP 603 TCVA S++ L V AP Sbjct: 615 TCVANTTLDSVSASAVLSVVAP 636 Score = 41.1 bits (92), Expect = 0.33 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE----WISVK-NITK 1435 PS P I+ S+ + WD P + N + Y ++YQ I++T + +K K Sbjct: 952 PSAPSSLKIVNPTLDSLTLEWDPPSHP-NGILTEYTLKYQPINSTHELGPLVDLKIPANK 1010 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 T+ +++NL ++ Y+F YA S + T E + E I P V Sbjct: 1011 TRWTLKNLNFSTRYKFYFYAQTSAG-SGSQITEEAVTTVDEAGILPPDV 1058 >UniRef50_Q4RRR9 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 875 Score = 93.5 bits (222), Expect = 6e-17 Identities = 139/652 (21%), Positives = 249/652 (38%), Gaps = 62/652 (9%) Query: 1339 DSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSIN 1398 D S+ LT+ K DAG+YK N A+ + V I K + P+ E I Sbjct: 65 DESSSILTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIA 124 Query: 1399 ICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 + E++ T+++ + ++I + + K ++ I+ +K + E Sbjct: 125 DIICDIESSPPPTVLWKY-KGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTC----E 179 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVE--KPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 + E ++VIK PT+ + N T + + ++LTC G P+P VTW Sbjct: 180 GRLMSRGEID--FRVIKVIVNVLPTIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWT 237 Query: 1517 RDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVET-------SCVVGI 1567 R+G L+ + + E+ Y CIA N GE E V+ Sbjct: 238 RNGVVLEAGEKYSFNEDGSEMTLLEVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVF 297 Query: 1568 QQKPVIT--ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNG-----------NKLE 1614 KP IT I+ ++ + +V +T G P P + W G N++ Sbjct: 298 AVKPKITYIINTTALETEEQV----TLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIY 353 Query: 1615 NDKEYNITTKE--KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 + N+ T+ + S + +K +K + + +Y A + G L+V P K G Sbjct: 354 QSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAP-KIHGD 412 Query: 1673 VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYC-IQKL 1731 V + +V I + + + P+ N V +Y I Sbjct: 413 VAVYTWEENAVNISCEVQAHPSDVSIVWLRDGLQLPNANA-TNVKIFRTPSSSYLQINPG 471 Query: 1732 NENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS 1791 +EN + A N +G ES+ ++ A +VPS + + I + Sbjct: 472 SENDFGSYNCTASNELG----TESKEFLLIQA-EVPSAPFIIEVRAF--STTAQIQFEEP 524 Query: 1792 EKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSI-----NTTYQFRIYARNEIG 1846 E GG P++ YKV+ + +G+ I +++I T+YQ ++ A N G Sbjct: 525 ESTGGVPVLKYKVQWRIKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAINGKG 584 Query: 1847 TSLPYTSDDKIT---------IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 +D T + P+ P+ E S+ + W + + +GGSPI Sbjct: 585 EGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKGNSMKVSWLK-QDDGGSPI 643 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVS 1949 +Y+I +K ++ W + + + + ++ E + AEN G S Sbjct: 644 LHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKS 695 Score = 91.5 bits (217), Expect = 2e-16 Identities = 75/292 (25%), Positives = 127/292 (43%), Gaps = 10/292 (3%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 TF P Q EG + C + + P P + W +KG +I D+++ S+ H Sbjct: 108 TFRNAPSPQEFTEGDIADIICDIESSPPPTVLWKYKGRKIQMDKDVRFKELSNNH----- 162 Query: 695 LKITNVKKFQEGTYTVVA-VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L+I +KK EG YT + GE ++ K+ +V + + G+ V Sbjct: 163 LQIRGIKKTDEGPYTCEGRLMSRGEIDFRVI-KVIVNVLPTIRVWQTEVNATADVGQPVK 221 Query: 754 LSAQVVGNPRPTITWCKNNKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAENSEG 812 L+ V G P P +TW +N ++A S + D +T+L+ K+ DEG YT A+N G Sbjct: 222 LTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDGSEMTLLEVAKL-DEGEYTCIAKNKAG 280 Query: 813 IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI 872 +E + V + A P ++ + + L + +P P+I+W + Sbjct: 281 ESEQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCEASGDPTPTISWSYGGNV 340 Query: 873 ISPSETITQNFDGENIE-LVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 S E N ++++ V+T D+ + S + K V AG+ AR I Sbjct: 341 FSEGEQAHLNRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAI 392 Score = 72.9 bits (171), Expect = 9e-11 Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 36/292 (12%) Query: 646 DEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQE 705 D G + L C + PEP + W G + E S + S + + V K E Sbjct: 215 DVGQPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYSFNEDG------SEMTLLEVAKLDE 268 Query: 706 GTYTVVAVNREGEASLPIVLKIKTGE---KEPPQVIEPLKSMIVRQGESVILSAQVVGNP 762 G YT +A N+ GE+ + L++ P++ + + + E V L+ + G+P Sbjct: 269 GEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCEASGDP 328 Query: 763 RPTITWCKN------------NKPVKALP----TKSDGDTHSITILKPKKVKDEGVYTLK 806 PTI+W N+ ++L T+SD S+ LK K D G Y Sbjct: 329 TPTISWSYGGNVFSEGEQAHLNRIYQSLDGNVVTRSDARVSSLN-LKHVKYTDAGQYLCT 387 Query: 807 AENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP-SIT 865 A ++ G E SA + V + + + ++ E+ + + V +P SI Sbjct: 388 ARSAIGEDEQSAYLEVRYAPKIHGDVAVY--------TWEENAVNISCEVQAHPSDVSIV 439 Query: 866 WYRNN-EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 W R+ ++ + + T + F + + N SE D G Y C ASN G S Sbjct: 440 WLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTASNELGTES 491 Score = 67.3 bits (157), Expect = 4e-09 Identities = 64/236 (27%), Positives = 111/236 (47%), Gaps = 25/236 (10%) Query: 1830 SINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVS-ESTSRSVTLKWTE 1888 S N + A NE+GT S + + I + PS P F++ + S + +++ E Sbjct: 472 SENDFGSYNCTASNELGTE----SKEFLLIQAEV--PSAP--FIIEVRAFSTTAQIQFEE 523 Query: 1889 PESNGGSPITNYIIEFKTVKGKS-WTKIV--TVGGSVHEHCIENIKEKDEIIFRISAENT 1945 PES GG P+ Y ++++ +KG+S WT+ V G+++E I +K + ++SA N Sbjct: 524 PESTGGVPVLKYKVQWR-IKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAING 582 Query: 1946 VGVSLPTESQSVRLE----------KHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGG 1995 G + + + E + A P+PP E+ G N + SW + DGG Sbjct: 583 KGEGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKG-NSMKVSWLKQD-DGG 640 Query: 1996 APLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSE 2051 +P+L Y I + + + W ++ N+ +R L + Y + + A NE G SE Sbjct: 641 SPILHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKSE 696 Score = 56.0 bits (129), Expect = 1e-05 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G V+ C V+GYP P +TW R +++ + + + +D + TL+ EV D G +TC Sbjct: 217 GQPVKLTCAVDGYPEPMVTWTRNGVVLEAGEKYS-FNEDGSEMTLL--EVAKLDEGEYTC 273 Query: 584 VAKNAAGFASSTTELIV 600 +AKN AG + L V Sbjct: 274 IAKNKAGESEQELSLRV 290 Score = 52.4 bits (120), Expect = 1e-04 Identities = 127/656 (19%), Positives = 255/656 (38%), Gaps = 79/656 (12%) Query: 874 SPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 SP T+T+N + +I L + +E D+G YKC+A+N ++ +V I +K+TF ++ Sbjct: 56 SPDITVTRNDESSSI-LTLYKAGTE-DAGVYKCIATNGDQQAESTVKVKI-FQKITF-RN 111 Query: 934 LQKSYETEEG--KTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXX 991 E EG +I + ++S + W + ++I MD +E Sbjct: 112 APSPQEFTEGDIADIICDIESSPPPTVLWKYKGRKIQ-MDKDVRFKELSNNHLQIRGIKK 170 Query: 992 XDVGVIKCIVK-----DQETSTMLVVKETIPEFIRKLQDFEVKEKDV---AILEVEINSE 1043 D G C + + + + V+ +P IR Q DV L ++ Sbjct: 171 TDEGPYTCEGRLMSRGEIDFRVIKVIVNVLPT-IRVWQTEVNATADVGQPVKLTCAVDGY 229 Query: 1044 TADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAE--- 1099 +V W R+G +++ + KY F + G ++ + + DEGEY+CI ++++ +E Sbjct: 230 PEPMVTWTRNGVVLEAGE-KYSFNEDG--SEMTLLEVAKLDEGEYTCIAKNKAGESEQEL 286 Query: 1100 -------VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGD--ALVRW------FKDGS 1144 V V + P+I + + + T E GD + W F +G Sbjct: 287 SLRVFDSVLVFAVKPKITYIINTTALETEEQVTLTCE-ASGDPTPTISWSYGGNVFSEGE 345 Query: 1145 EIQFSNHIQLTIDG--------KKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVE 1192 + N I ++DG + L + DAG+Y C +G + +A L V Sbjct: 346 QAHL-NRIYQSLDGNVVTRSDARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVR 404 Query: 1193 -EPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTE--KFTLISDVK 1249 P I+ + + + N V+ + + W + + + + Sbjct: 405 YAPKIHGDVAVYTWEENAVNISC--EVQAHPSDVSIVWLRDGLQLPNANATNVKIFRTPS 462 Query: 1250 KRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYR-IKRGSDVTLL 1308 L I +E+D Y C + T + +++ + E R + + Sbjct: 463 SSYLQINPGSENDFGSYNCTASNELGTESKEFLLIQAEVPSAPFIIEVRAFSTTAQIQFE 522 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI-YKLRLENNCG 1367 P ++ V +I + T+ D + ++ + Y+++L G Sbjct: 523 EPESTGGVPVLKYKVQWRIKGRSSWTQGVYDIQQGTINEVTITGLKPETSYQVQLSAING 582 Query: 1368 HADVEMNVTILDKPSP-----------PGKPNILEID------SSSINICWDEPENTGNS 1410 + E + K P G PN ++D +S+ + W + ++ G S Sbjct: 583 KGEGESSAADFFKTEPVNGLYHYFSEDAGNPNPPKVDGELEPKGNSMKVSWLK-QDDGGS 641 Query: 1411 TIIYYVVEYQEIDTTEW-ISVKNITKTQ-TSIQNLKTNSSYRFRAYAVNEVDISDA 1464 I++Y++ Y+ + ++EW ++ + ++ ++ L+ ++ Y A NE S+A Sbjct: 642 PILHYLIRYKPLQSSEWKPEIRMPSNSEYVVLRGLEWDTEYSVHVVAENEKGKSEA 697 Score = 52.4 bits (120), Expect = 1e-04 Identities = 103/486 (21%), Positives = 192/486 (39%), Gaps = 51/486 (10%) Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV-VELPPEIITRL--QNQKVNKGNKATFEIEL 1130 L + D G Y CI + AE TV V++ +I R Q+ +G+ A ++ Sbjct: 71 LTLYKAGTEDAGVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIADIICDI 130 Query: 1131 TKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG-NSKCTAI 1188 V W G +IQ ++ + L+I D G Y+CE S+ Sbjct: 131 ESSPPPTVLWKYKGRKIQMDKDVRFK-ELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEID 189 Query: 1189 LTVEEPSINF--TLRLPEFILVPANTDAYLTVEIP------DETLDVTWYKKKSVIEDTE 1240 V + +N T+R+ + V A D V++ E + VTW + V+E E Sbjct: 190 FRVIKVIVNVLPTIRVWQ-TEVNATADVGQPVKLTCAVDGYPEPM-VTWTRNGVVLEAGE 247 Query: 1241 KFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVE------FPPKIVD 1292 K++ D + TL+ + + D+ EYTC+ + +S +L + V + PKI Sbjct: 248 KYSFNEDGSEMTLL--EVAKLDEGEYTCIAKNKAGESEQELSLRVFDSVLVFAVKPKITY 305 Query: 1293 YEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCK-------------HTKPSID 1339 ++ VTL + P P W + + + + D Sbjct: 306 IINTTALETEEQVTLTCEASGDPTPTISWSYGGNVFSEGEQAHLNRIYQSLDGNVVTRSD 365 Query: 1340 SKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINI 1399 ++ +SL +K V+ TDAG Y + G + + + P G + + +++NI Sbjct: 366 ARVSSLNLKHVKYTDAGQYLCTARSAIGEDEQSAYLEVRYAPKIHGDVAVYTWEENAVNI 425 Query: 1400 CWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAY---AV 1456 + + + +I+ ++ + ++ +VK +S + S F +Y A Sbjct: 426 SCEVQAHPSDVSIV-WLRDGLQLPNANATNVKIFRTPSSSYLQINPGSENDFGSYNCTAS 484 Query: 1457 NEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP--QPKVT 1514 NE+ +E+ E+ ++ + ++ S ++ +T E GGVP + KV Sbjct: 485 NEL----GTESKEF--LLIQAEVPSAPFIIEVRAFSTTAQIQFEEPESTGGVPVLKYKVQ 538 Query: 1515 WYRDGK 1520 W G+ Sbjct: 539 WRIKGR 544 Score = 50.0 bits (114), Expect = 7e-04 Identities = 58/273 (21%), Positives = 101/273 (36%), Gaps = 12/273 (4%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTI---DGKKQKLKIYDCDLDDA 1173 +++ G F E+ + WF + N +T+ D L +Y +DA Sbjct: 22 EISLGESKFFMCEVAGVAKHIDWFGPSGDRIEQNSPDITVTRNDESSSILTLYKAGTEDA 81 Query: 1174 GEYSCEVGNSKCTAILTVEEPSI-NFTLR-LPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 G Y C N A TV+ T R P A + +I +K Sbjct: 82 GVYKCIATNGDQQAESTVKVKIFQKITFRNAPSPQEFTEGDIADIICDIESSPPPTVLWK 141 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV-LLDAKSTTKLKV--EVVEFPP 1288 K +K ++ L IR + D+ YTC L ++ +V +V P Sbjct: 142 YKGRKIQMDKDVRFKELSNNHLQIRGIKKTDEGPYTCEGRLMSRGEIDFRVIKVIVNVLP 201 Query: 1289 KIVDYEREYRIKR--GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 I ++ E G V L +P+P W N +++ + K S + + +T Sbjct: 202 TIRVWQTEVNATADVGQPVKLTCAVDGYPEPMVTWTRNGVVLEAGE--KYSFNEDGSEMT 259 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 + +V D G Y +N G ++ E+++ + D Sbjct: 260 LLEVAKLDEGEYTCIAKNKAGESEQELSLRVFD 292 Score = 40.7 bits (91), Expect = 0.43 Identities = 31/130 (23%), Positives = 55/130 (42%), Gaps = 4/130 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTA--IIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 G + F C+V G + I WF + I + S D + +D++ + L + + EDAG + Sbjct: 26 GESKFFMCEVAGVAK-HIDWFGPSGDRIEQNSPDITVTRNDESSSILTLYKAGTEDAGVY 84 Query: 582 TCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPK 641 C+A N A ST ++ + ++ + + DI PPT K K Sbjct: 85 KCIATNGDQQAESTVKVKIFQKITFRNAP-SPQEFTEGDIADIICDIESSPPPTVLWKYK 143 Query: 642 AQYVDEGSDI 651 + + D+ Sbjct: 144 GRKIQMDKDV 153 >UniRef50_A7RYG4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 760 Score = 93.5 bits (222), Expect = 6e-17 Identities = 106/452 (23%), Positives = 177/452 (39%), Gaps = 47/452 (10%) Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 Y V Y D ++ S + I+K ++ SS RF Y N S + E KV Sbjct: 272 YTCVAYNIRDYSDSASAE-ISKVYV-LEQRSPRSSVRFAIYPANN------SASAEISKV 323 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 I KP+ + E +E L C+ G P P+V W RDG+ + + T R Sbjct: 324 FVRPSI------KPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRR 377 Query: 1534 XXXXXXXXXXXXXX-YKCIAFNDHGEVETSCVVG-------IQQKPVITISNEDIKQKHK 1585 Y C A N+ + E +V I+ P + + Sbjct: 378 SRIYIQDVRLEDEGRYTCEARNNARDQEGHPIVATEEIGLYIKSLPRLNKKGTPLTVYSY 437 Query: 1586 VGDEW--LVTAVIEGIPPPEV-IWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSK 1642 +G+ + +G P P V IW+ N ++ N E+ + I EL+ Sbjct: 438 LGNPKPVFIRCRFDGYPFPNVTIWFDN-KQIANGTEFAMFD------IITNELE--DFGD 488 Query: 1643 YTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYA 1702 Y + N G+ +V V L +PS+P + ++ VT+ W PP+DDGG+E+ +Y Sbjct: 489 YLCWSWNIHGSKNVTVKLTHAREPSRPVN--VKANVTCSRVTLTWDPPIDDGGMEIMQYV 546 Query: 1703 IEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSE-ALESEPIVIK 1761 IE K+ + + Y I L + Y ++ A+N +G + E+ I+ + Sbjct: 547 IEYDG-------KIFNTEDTYPKYYITNLKRDTMYDIKIWARNKMGKGKNNYETVSIITQ 599 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXX 1821 ID+ + ++ W E NGG P + YKV + ++ + Sbjct: 600 KYCPPSRPIIWFPYEKVIDDTAFFLKWHEPESNGGDPDVRYKVVVSEDLDEGPFAIKTEF 659 Query: 1822 XXAR---IQKLSINTTYQFRIYARNEIGTSLP 1850 R + +L YQ +++ N+ G S P Sbjct: 660 TALREYYVDELKFGQRYQLEVFSYNKAGMSEP 691 Score = 63.3 bits (147), Expect = 7e-08 Identities = 54/205 (26%), Positives = 92/205 (44%), Gaps = 18/205 (8%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 PS+P N + + SR VTL W P +GG I Y+IE+ KI + ++ Sbjct: 512 PSRPVNVKANVTCSR-VTLTWDPPIDDGGMEIMQYVIEYD-------GKIFNTEDTYPKY 563 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTA--PLEIRMVGSNI 1982 I N+K +I A N +G E+ S+ +K+ PS P P E +++ Sbjct: 564 YITNLKRDTMYDIKIWARNKMGKGKNNYETVSIITQKYCP-PSRPIIWFPYE-KVIDDTA 621 Query: 1983 VMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK-FNIRDLSENHTYMIRI 2041 W PE +GG P + Y + + + + K + L+ + + +L Y + + Sbjct: 622 FFLKWHEPESNGGDPDVRYKVVVSEDLDEGPFAI-KTEFTALREYYVDELKFGQRYQLEV 680 Query: 2042 YARNEIGLSEPLESDEPFKVIPGEG 2066 ++ N+ G+SEP + + IP EG Sbjct: 681 FSYNKAGMSEPAIA---YYFIPNEG 702 Score = 59.7 bits (138), Expect = 9e-07 Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 7/170 (4%) Query: 1784 VYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARN 1843 V +TW P +GG I+ Y +E +GK + I L +T Y +I+ARN Sbjct: 527 VTLTWDPPIDDGGMEIMQYVIEY--DGKIFNTEDTYPKYY--ITNLKRDTMYDIKIWARN 582 Query: 1844 EIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSEST--SRSVTLKWTEPESNGGSPITNYI 1901 ++G I I + PPS+P + E + LKW EPESNGG P Y Sbjct: 583 KMGKGKNNYETVSI-ITQKYCPPSRPIIWFPYEKVIDDTAFFLKWHEPESNGGDPDVRYK 641 Query: 1902 IEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLP 1951 + + I T ++ E+ ++ +K + + N G+S P Sbjct: 642 VVVSEDLDEGPFAIKTEFTALREYYVDELKFGQRYQLEVFSYNKAGMSEP 691 Score = 48.0 bits (109), Expect = 0.003 Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 16/190 (8%) Query: 738 IEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV 797 I+P+ +V E L GNP P + W ++ + + G I I + ++ Sbjct: 329 IKPMYDEVVEIDEQAYLDCVGEGNPLPEVRWIRDGRYERRQQITLGGRRSRIYI-QDVRL 387 Query: 798 KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITV-KEKGTIKLV--- 853 +DEG YT +A N+ E ++ EE P + +TV G K V Sbjct: 388 EDEGRYTCEARNNARDQEGHPIVATEEIGLYIKSLPRLNKKGTPLTVYSYLGNPKPVFIR 447 Query: 854 ARVTRNPVPSIT-WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSA 912 R P P++T W+ N +I + +E FD +ITN + E D GDY C + N Sbjct: 448 CRFDGYPFPNVTIWFDNKQIANGTEFAM--FD------IITN-ELE-DFGDYLCWSWNIH 497 Query: 913 GKSSHGARVT 922 G + ++T Sbjct: 498 GSKNVTVKLT 507 Score = 47.2 bits (107), Expect = 0.005 Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 8/124 (6%) Query: 1063 YDFEKRGHIRKLYI-RNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKG 1121 Y I K+Y+ S ++ + S +AE++ V + P I + ++ V Sbjct: 282 YSDSASAEISKVYVLEQRSPRSSVRFAIYPANNSASAEISKVFVRPSI-KPMYDEVVEID 340 Query: 1122 NKATFEIELTKGDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCE 1179 +A + + +G+ L VRW +DG ++ Q+T+ G++ ++ I D L+D G Y+CE Sbjct: 341 EQAYLDC-VGEGNPLPEVRWIRDG---RYERRQQITLGGRRSRIYIQDVRLEDEGRYTCE 396 Query: 1180 VGNS 1183 N+ Sbjct: 397 ARNN 400 Score = 45.6 bits (103), Expect = 0.015 Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 27/270 (10%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 + G +++++C + E W ++G +P ++ S+ L + N+ Sbjct: 32 ISAGKNLVIKCTISG--EQFQGW-YRGGSKIPTDSSQTKYVSNPTSGAYQLHLNNIVVAD 88 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRP 764 G Y + G + + + T E Q + R + ++ V G P+P Sbjct: 89 GGEY--ICRGNRGSKTFQLYVDFTTTHVELIQYL--------RISNADMIDIDVYGYPKP 138 Query: 765 TITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLK-AENSEGIAETS--AVI 820 T W KN +P + S D S+ + ++ D+G YT A ++ G++ VI Sbjct: 139 TFVWTKNGQPWNPNEGRFSTQDGGSVKFSR-VEISDQGNYTCTIAVDTLGLSSVKKIEVI 197 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 T E P E P NR +TV T + P P W N+I+ + Sbjct: 198 TFEPP--RLIERPAPFNRL--LTVGYNTTFH--CKAEGYPKPKYRWL--NQIMREVDLSN 249 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASN 910 F + ITN+ D G+Y CVA N Sbjct: 250 PRFTVADEYFHITNIQLS-DVGNYTCVAYN 278 Score = 44.8 bits (101), Expect = 0.026 Identities = 54/249 (21%), Positives = 91/249 (36%), Gaps = 19/249 (7%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G F C+ EGYP+P+ W Q + + D+ I + D G +TC Sbjct: 218 GYNTTFHCKAEGYPKPKYRWLNQIMREVDLSNPRFTVADE---YFHITNIQLSDVGNYTC 274 Query: 584 VAKNAAGFA-SSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKA 642 VA N ++ S++ E+ L +V A+I + K Sbjct: 275 VAYNIRDYSDSASAEISKVYVLEQRSPRSSVRFAIYPANNSASAEISKVFVRPSIKPMYD 334 Query: 643 QYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 + V+ L+C P P++ W+ G + + + S + I +V+ Sbjct: 335 EVVEIDEQAYLDCVGEGNPLPEVRWIRDGRY---ERRQQITLGGRR----SRIYIQDVRL 387 Query: 703 FQEGTYTVVAVNR-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 EG YT A N + PIV + G I+ L + + + S +GN Sbjct: 388 EDEGRYTCEARNNARDQEGHPIVATEEIG-----LYIKSLPRLNKKGTPLTVYS--YLGN 440 Query: 762 PRPTITWCK 770 P+P C+ Sbjct: 441 PKPVFIRCR 449 Score = 38.7 bits (86), Expect = 1.7 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 8/110 (7%) Query: 1351 ENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 E D G Y N G +V + +T +PS P + S + + WD P + G Sbjct: 482 ELEDFGDYLCWSWNIHGSKNVTVKLTHAREPSRPVNVKA-NVTCSRVTLTWDPPIDDGGM 540 Query: 1411 TIIYYVVEYQ-EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEV 1459 I+ YV+EY +I TE T + I NLK ++ Y + +A N++ Sbjct: 541 EIMQYVIEYDGKIFNTE------DTYPKYYITNLKRDTMYDIKIWARNKM 584 >UniRef50_UPI0000E48C89 Cluster: PREDICTED: similar to Nr-CAM protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Nr-CAM protein - Strongylocentrotus purpuratus Length = 1235 Score = 92.7 bits (220), Expect = 1e-16 Identities = 143/615 (23%), Positives = 228/615 (37%), Gaps = 61/615 (9%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+ ++P++ D + L CR IPEP W G D N +++ Sbjct: 22 VPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDRASLDG----- 76 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLK----IKTGEKEPPQVI--EPLKSMI 745 L I ++ +G Y A NR G A ++ + E P+ I + + + Sbjct: 77 -GNLVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVDQGRPLK 135 Query: 746 VRQGESVILSAQVVGNPRPTITWC-KNNKPVK-ALPTKSDGDTHSITILKPKKVKD-EGV 802 +R G S GNP P I W KP + + D + D +G Sbjct: 136 LRCGGS---PGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDAKGY 192 Query: 803 YTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVP 862 Y N G ++ + +T+ E A + EI ++ + KL P P Sbjct: 193 YCQAINNVVGSSQRTPKVTLMVSVESGAS-LITKPAANEIAIRTQ-LFKLKCIAYGYPTP 250 Query: 863 SITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 ITW R E + ++ G+ ELVI+ V++ D G Y CVASN+ G VT Sbjct: 251 VITWKRGEEQLQSGGRVSIEESGQ--ELVISTVENS-DKGTYTCVASNTGGDDEFSTVVT 307 Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMD-----HREI 975 VE + G++V +EC++ + W N + + + R Sbjct: 308 --VESAPYFPAPPSDETKGPGESVDIECRSEGVPAPAVDWLVNGQPWADFESNIDTERWT 365 Query: 976 IQEG--RXXXXXXXXXXXXDVGVIKCIV----KDQETSTML---VVKETIPEFIRKLQDF 1026 + G + D V +CI K++ TS +L + IP F + Sbjct: 366 VVTGNPQLATISISNLQTTDSNVFQCIATNKYKEELTSVVLNVVSIPARIPSFTPVTRKL 425 Query: 1027 EVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 V E A + T + W G ++ +KY ++ + I N D G Sbjct: 426 SVVEDSSAAFTCHVEGRPTPTITWTFKGSVL-TNGDKYTIDELA--GSIVINNALEVDSG 482 Query: 1086 EYSCIL------RDESCTAEVTVVELPPEIIT-RLQNQKVNKGNKATFEIELTKGDALVR 1138 Y C +D T T+ L IIT + V + ATF+ E+T L + Sbjct: 483 AYECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHELDK 542 Query: 1139 ----WFKDGSEIQFSNHIQLTIDGKK-QKLKIYDCDLDDAGEYSCEVGNS-KCTAILTVE 1192 W KDG ++ + L ID Y C ++ + S + +S +A L V+ Sbjct: 543 PETYWMKDGQRLEANQDNSLRIDNAMFSNSGTYTCFVETTLDESTDTVHSVNASAQLVVK 602 Query: 1193 ---EPSINFTLRLPE 1204 P N LR E Sbjct: 603 GHPGPPQNLQLRAKE 617 Score = 77.8 bits (183), Expect = 3e-12 Identities = 215/1035 (20%), Positives = 370/1035 (35%), Gaps = 113/1035 (10%) Query: 1096 CTAEVTVV-ELPPEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQ 1153 C A +T+ ++PP I+ + ++ + T T + W+KDG+ N+ + Sbjct: 12 CIATLTLAYDVPPSIVEQPESINGDTRLPLTLTCRATGIPEPSYYWYKDGALFDVDNNDR 71 Query: 1154 LTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTA----ILTVEEPSINFTLRLPEFILVP 1209 ++DG L I D G+Y C N TA I+T F PE I V Sbjct: 72 ASLDGGN--LVIESLTTADDGQYQCFANNRLGTAMSQKIMTSLAFMDQFENTAPETIQVD 129 Query: 1210 ANTDAYL----TVEIPDETLDVTWYKKKSVIEDTEKF--TLISDVKKRTLIIRKCTEDDQ 1263 L + +P+ Y + + T I+ + L+ D Sbjct: 130 QGRPLKLRCGGSPGVPNGNPAPLIYWTDAAAKPTPITYNARINQDPEGNLVFSNVIASDA 189 Query: 1264 CEYTC-----VLLDAKSTTKLKVEV-VEFPPKIVDYEREYRIKRGSDVTLL--VDYQAFP 1315 Y C V+ ++ T K+ + V VE ++ I + + L + Y +P Sbjct: 190 KGYYCQAINNVVGSSQRTPKVTLMVSVESGASLITKPAANEIAIRTQLFKLKCIAY-GYP 248 Query: 1316 QPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNV 1375 P W + ++ + SI+ L I VEN+D G Y N G + V Sbjct: 249 TPVITWKRGEEQLQS--GGRVSIEESGQELVISTVENSDKGTYTCVASNTGGDDEFSTVV 306 Query: 1376 TILDKPSPPGKPNI-LEIDSSSINI-CWDEPENTGNSTIIYYV-----VEYQE-IDTTEW 1427 T+ P P P+ + S++I C E + + V +++ IDT W Sbjct: 307 TVESAPYFPAPPSDETKGPGESVDIEC--RSEGVPAPAVDWLVNGQPWADFESNIDTERW 364 Query: 1428 ISVKNITKTQT-SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEK 1486 V + T SI NL+T S F+ A N+ E T + + P+ Sbjct: 365 TVVTGNPQLATISISNLQTTDSNVFQCIATNKYK----EELTSVVLNVVSIPARIPSFTP 420 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA-KATYENRXXXXXXXXXXXXX 1545 + ++ + TC G P P +TW G L K T + Sbjct: 421 VTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGSVLTNGDKYTIDELAGSIVINNALEVD 480 Query: 1546 X-XYKCIAFN--DHGEVET--SCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG-I 1599 Y+C A N D + E S + + K +IT+ D+ + + + + Sbjct: 481 SGAYECTAENSIDGQDYEATGSATLTVLGKTIITLPPADLTVREDTTATFQCEITYDHEL 540 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI-------EASNTAG 1652 PE W K+G +LE +++ ++ RI S+S YT E+++T Sbjct: 541 DKPETYWMKDGQRLEANQDNSL---------RIDNAMFSNSGTYTCFVETTLDESTDTVH 591 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 + + L V P P+ + + ++ + W+P +D + Y I+ + + Sbjct: 592 SVNASAQLVVKGHPGPPQNLQLRAKEQEFAMDLFWEPG-NDNNAPIQYYIIQY----DTK 646 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXX 1772 W AD+ + + +Y FRVIA N +G SE + + PS Sbjct: 647 W---ADMHWQFQAPFV-------DYQFRVIAVNEIGRSEPSAGVAPTVDPQVAPPSKNPI 696 Query: 1773 XXXXXXIDNESVYITWFPSEK--NGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXAR-- 1825 ES+ I W GG + Y+ + E K A Sbjct: 697 EVSGSGTRPESMVIRWQSIHPFYYGGDDFHYEVAYRPRMSSE-PFVKDTVYPENTDANPT 755 Query: 1826 --IQKLSINT-----TYQFRIYARNEIGTSLPYTSDDKITIGKT--LTPPSQPRNFVVSE 1876 IQ +N Y+F + + N G + +I G + P + P V Sbjct: 756 GIIQNFIVNARKPYEEYEFSVRSMNSGGPG----PEPEIHYGFSGEAAPGASPSGVTVEA 811 Query: 1877 STSRSVTLKW--TEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 ++ V + W +PE G + Y + + K + V + N++ Sbjct: 812 ISANEVNVTWEPIDPEDANGK-LGGYNVYYNVKIASGQDKQMCVKSPC---VVGNLQAAT 867 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDG 1994 + A G ++ V + + P P L++ + +V+ +W P Sbjct: 868 TYEITVKAFTNAGEGPASDVVEVVTD---SAPPGPVYKLKVDVYSYRLVL-NWQEPILTN 923 Query: 1995 GAPLLGYNIAIRDVT-KTMWMEVG-KVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 G L GYN+ I V +T+ E + V+ I + S Y + + A N IG E Sbjct: 924 G-DLTGYNVIITPVVDETLGDEENFPLAVDDDLTLIYEASPETKYRVEVLALNTIGDGEK 982 Query: 2053 LESDEPFKVIPGEGS 2067 ++EP + G S Sbjct: 983 -TTEEPTTFLQGRPS 996 Score = 45.6 bits (103), Expect = 0.015 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F R + S+ F C VEG P P ITW + +++ + + D+ ++V Sbjct: 416 PSFTPVTRKLSVVEDSSAAFTCHVEGRPTPTITWTFKGSVLTNGDKYTI---DELAGSIV 472 Query: 570 IREVFPEDAGTFTCVAKNA 588 I D+G + C A+N+ Sbjct: 473 INNALEVDSGAYECTAENS 491 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + +C GYP P ITW R ++ + +++ LVI V D GT+TCVA N Sbjct: 239 KLKCIAYGYPTPVITWKRGEEQLQSGGRVSI---EESGQELVISTVENSDKGTYTCVASN 295 Query: 588 AAGFASSTTELIVEA 602 G +T + VE+ Sbjct: 296 TGGDDEFSTVVTVES 310 >UniRef50_UPI0000DA2C8C Cluster: PREDICTED: similar to myosin binding protein C, slow type; n=1; Rattus norvegicus|Rep: PREDICTED: similar to myosin binding protein C, slow type - Rattus norvegicus Length = 1162 Score = 92.7 bits (220), Expect = 1e-16 Identities = 50/157 (31%), Positives = 86/157 (54%), Gaps = 3/157 (1%) Query: 1038 VEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT 1097 VE+ +V W ++G+ I+P KY FE +G+ R ++I N ++ D+ EY DE C+ Sbjct: 300 VELADPKLEVKWFKNGQEIRPS-TKYIFEHKGNERIMFINNCALTDDSEYYVTAGDEKCS 358 Query: 1098 AEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEI--QFSNHIQLT 1155 E+ V E P + +L++ G + E+E+++ DA V+WFK+G EI + ++ Sbjct: 359 TELFVREPPIMVTKQLEDMNAYCGERVELEVEVSEDDANVKWFKNGEEIVPGPKSRYRIK 418 Query: 1156 IDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVE 1192 ++GKK L I D+ EYS + +A L+V+ Sbjct: 419 VEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKLSVD 455 Score = 86.2 bits (204), Expect = 9e-15 Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 3/168 (1%) Query: 1117 KVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 +++KG + F +EL V+WFK+G EI+ S G ++ + I +C L D EY Sbjct: 289 QIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCALTDDSEY 348 Query: 1177 SCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK--KKS 1234 G+ KC+ L V EP I T +L E + L VE+ ++ +V W+K ++ Sbjct: 349 YVTAGDEKCSTELFVREPPIMVTKQL-EDMNAYCGERVELEVEVSEDDANVKWFKNGEEI 407 Query: 1235 VIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 V ++ + + KK TLII T+ D EY+ + +S+ KL V+ Sbjct: 408 VPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKLSVD 455 Score = 59.7 bits (138), Expect = 9e-07 Identities = 43/182 (23%), Positives = 78/182 (42%), Gaps = 2/182 (1%) Query: 923 IDVEKVTFVKHLQKSYETEEGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRX 981 ++ + F K L +Y+ ++G V + + + KW+ N +EI +G Sbjct: 273 VEKKSAAFAKILDPAYQIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNE 332 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEIN 1041 D D++ ST L V+E ++L+D + LEVE++ Sbjct: 333 RIMFINNCALTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVELEVEVS 392 Query: 1042 SETADVVWERDGEIIKP-KKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEV 1100 + A+V W ++GE I P K++Y + G L I + D EYS + +A++ Sbjct: 393 EDDANVKWFKNGEEIVPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKL 452 Query: 1101 TV 1102 +V Sbjct: 453 SV 454 Score = 44.0 bits (99), Expect = 0.046 Identities = 41/172 (23%), Positives = 65/172 (37%), Gaps = 5/172 (2%) Query: 1191 VEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 VE+ S F L + VE+ D L+V W+K I + K+ + Sbjct: 273 VEKKSAAFAKILDPAYQIDKGGRVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNE 332 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVD 1310 R + I C D EY D K +T+L V E P + + G V L V+ Sbjct: 333 RIMFINNCALTDDSEYYVTAGDEKCSTELFVR--EPPIMVTKQLEDMNAYCGERVELEVE 390 Query: 1311 YQAFPQPNDEWIVN-SKIIKKCK-HTKPSIDSKSASLTIKKVENTDAGIYKL 1360 N +W N +I+ K + ++ K +L I+ D+ Y + Sbjct: 391 VSE-DDANVKWFKNGEEIVPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSV 441 >UniRef50_Q4SW90 Cluster: Chromosome undetermined SCAF13667, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13667, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1278 Score = 92.3 bits (219), Expect = 1e-16 Identities = 75/297 (25%), Positives = 130/297 (43%), Gaps = 24/297 (8%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + PT S+ K V G +LLEC +P P I W KG ++ P+ + + Sbjct: 326 LSPTGSQSSKM--VLRGQQLLLECIAAGVPTPTIKWYRKGGDL-PERKVK------FENF 376 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L + V + G Y +A+N +G I++++K P ++ ++++ E+ Sbjct: 377 NKTLLVVGVSEEDAGEYVCMAINHQGSIRHSILVQVKAA----PYWLDKPTNLVLAPNEN 432 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITIL-KPKKVKDEGVYTLKAENS 810 L + GNP+P I W N +P+++ P D TI+ + ++ VY A N Sbjct: 433 GRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVLGDTIIFRSVQMGSSAVYQCNASNQ 492 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G ++A ++V + P + + Q I V E L +P+P + W++N Sbjct: 493 YGYLLSNAFVSVLD-----MPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNG 547 Query: 871 EIISPSETITQNFD-GENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE 926 + S ++ N L I SE D G Y CVAS+ GK+ + R+ + E Sbjct: 548 Q---GSGVDGGHYSVHNNGTLEIKRARSE-DEGTYTCVASSLLGKAENQVRLEVKEE 600 Score = 83.4 bits (197), Expect = 6e-14 Identities = 95/441 (21%), Positives = 167/441 (37%), Gaps = 37/441 (8%) Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE 1530 + ++ + K ++KP N+ PNE+ L C G P+P + W +G+ ++++ Sbjct: 406 HSILVQVKAAPYWLDKPT-NLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPS 464 Query: 1531 NRXXXXXXXXXXX---XXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVG 1587 Y+C A N +G + ++ V + P + ++ K Sbjct: 465 RDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIEN 524 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDK-EYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 + + G P P++ W+KNG D Y++ + IK + YT Sbjct: 525 NHTFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSV---HNNGTLEIKRARSEDEGTYTCV 581 Query: 1647 ASNTAGTSSVEVTLKVYDK------------PSKPEGPVIM--REISRESVTIEWKPPLD 1692 AS+ G + +V L+V ++ P +P+ P+ + + + SV + W P + Sbjct: 582 ASSLLGKAENQVRLEVKEEASLNPSVSSALPPDRPDPPLELDLSDPAVRSVRLTWIPG-N 640 Query: 1693 DGGLELTKYAIEKHEP--DNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFS 1750 D +T + ++ E + RW ++ + + +Q L Y FRVIA N VG S Sbjct: 641 DNRSPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQ-LAPFVNYQFRVIAINSVGQS 699 Query: 1751 EALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEKNGGSPIIDYKVEIK 1807 E P KT+ P ++ ITW P E+NG + + K Sbjct: 700 EPSLPSP-QYKTSGAAPDVIPRGLRGWGSMKGNMEITWEPLLDLERNGANLYYSVWWKRK 758 Query: 1808 QEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKT--LTP 1865 + W + YQ +I A NE G+ + I IG + TP Sbjct: 759 DTSEDWNNVTTVRTKHV-VHNTETYVPYQIKIQAGNEFGSG----PESNIIIGYSGEDTP 813 Query: 1866 PSQPRNFVVSESTSRSVTLKW 1886 P VS + + W Sbjct: 814 TDAPTELRVSRVDTNRAHIHW 834 Score = 64.1 bits (149), Expect = 4e-08 Identities = 48/193 (24%), Positives = 73/193 (37%), Gaps = 6/193 (3%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXX 1539 SPT + K + + + L CI GVP P + WYR G L K +EN Sbjct: 327 SPTGSQSSKMVLR--GQQLLLECIAAGVPTPTIKWYRKGGDLPERKVKFENFNKTLLVVG 384 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGI 1599 Y C+A N G + S +V ++ P ++ + A G Sbjct: 385 VSEEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRA--NGN 442 Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P + W NG +E+ + N + I + ++ S+ Y ASN G Sbjct: 443 PKPNIQWLINGQPIESSPQ-NPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAF 501 Query: 1660 LKVYDKPSKPEGP 1672 + V D P + GP Sbjct: 502 VSVLDMPPRMLGP 514 Score = 57.6 bits (133), Expect = 4e-06 Identities = 88/447 (19%), Positives = 184/447 (41%), Gaps = 41/447 (9%) Query: 1057 KPKKNKYDFEKRGHIRKL---YIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEII--T 1111 +P ++ D + G + K+ Y+ + S ++ E + + C + + P ++ T Sbjct: 273 RPDQDGLDMPREGLVNKMVERYLESNSQAEDPEEGLM---DGCGRSRKLPQTMPTLLSPT 329 Query: 1112 RLQNQK-VNKGNKATFE-IELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCD 1169 Q+ K V +G + E I ++W++ G ++ ++ + + L + Sbjct: 330 GSQSSKMVLRGQQLLLECIAAGVPTPTIKWYRKGGDLP---ERKVKFENFNKTLLVVGVS 386 Query: 1170 LDDAGEYSCEVGNSKCTA--ILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL-D 1226 +DAGEY C N + + + V+ + + L P +++ N + L + Sbjct: 387 EEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNLVLAPNENGRLVCRANGNPKPN 446 Query: 1227 VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVV 1284 + W IE + + DV T+I R Y C + + V V+ Sbjct: 447 IQWLINGQPIESSPQ-NPSRDVLGDTIIFRSVQMGSSAVYQCNASNQYGYLLSNAFVSVL 505 Query: 1285 EFPPKIVDYEREY-RIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA 1343 + PP+++ + + ++ + L + P P+ W N + S+ + + Sbjct: 506 DMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQG-SGVDGGHYSVHN-NG 563 Query: 1344 SLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPS---------PPGKPNI-LEID 1393 +L IK+ + D G Y + G A+ ++ + + ++ S PP +P+ LE+D Sbjct: 564 TLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSSALPPDRPDPPLELD 623 Query: 1394 SS-----SINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTS-IQNLKT 1445 S S+ + W P N S + +++V+++E + W ++ + S I L Sbjct: 624 LSDPAVRSVRLTWI-PGNDNRSPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQLAP 682 Query: 1446 NSSYRFRAYAVNEVDISDASETTEYYK 1472 +Y+FR A+N V S+ S + YK Sbjct: 683 FVNYQFRVIAINSVGQSEPSLPSPQYK 709 Score = 54.0 bits (124), Expect = 4e-05 Identities = 120/580 (20%), Positives = 205/580 (35%), Gaps = 41/580 (7%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVF---PED-AGTFTCVA 585 EC+ +G P P +W R +D ++ D+ TL I ED G + C A Sbjct: 24 ECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDS-GTLEINFRSGGKQEDYEGEYQCFA 82 Query: 586 KNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKP-KAQY 644 N G A S ++++ D A LE P + K+ Sbjct: 83 SNELGVALSN-KILLRVSSEDTLLNTCRFSHSSVVSDCFCATTLEA--PLWPKEVLDPVL 139 Query: 645 VDEGSDILLECRLV-AIPEPDIAWLFKG-EEIVPDENISVAIESDMHMYCSVLKIT-NVK 701 V EGS ++L C +P P I W+ IV D+ +S+ + D++ + K N Sbjct: 140 VTEGSSLILPCNPPPGLPPPLIFWMDSTMTPIVQDKRVSMGLNGDLYFSNVMAKDAHNEY 199 Query: 702 KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGN 761 K + ++ P +LK+ T KEP + + GE + + Sbjct: 200 KCNARCRLTQTIQQKN----PFILKVHT--KEPFN--DTSHNDTDPYGEDEEDARGQISQ 251 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEGVYTLKAEN-SEGIAET 816 P I + PV+ K D + + L K V+ +AE+ EG+ + Sbjct: 252 ISPLIVKRASVHPVRCCGGKERPDQDGLDMPREGLVNKMVERYLESNSQAEDPEEGLMDG 311 Query: 817 SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPS 876 T P + + ++ ++ +A P P+I WYR + Sbjct: 312 CGRSRKLPQTMPTLLSPTGSQSSKMVLRGQQLLLECIAAGV--PTPTIKWYRKGGDLPER 369 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQK 936 + +NF N L++ V SE D+G+Y C+A N G H V + K Sbjct: 370 KVKFENF---NKTLLVVGV-SEEDAGEYVCMAINHQGSIRHSILVQVKAAPYWLDKPTNL 425 Query: 937 SYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGV 996 E ++ + + +W N + I ++ V Sbjct: 426 VLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNP-SRDVLGDTIIFRSVQMGSSAV 484 Query: 997 IKCIVKDQE----TSTMLVVKETIPEFI-RKLQDFEVKEKDVAILEVE-INSETADVVWE 1050 +C +Q ++ + V + P + K Q +V E + L+ S D+ W Sbjct: 485 YQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWF 544 Query: 1051 RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 ++G+ Y G L I+ DEG Y+C+ Sbjct: 545 KNGQGSGVDGGHYSVHNNG---TLEIKRARSEDEGTYTCV 581 Score = 50.0 bits (114), Expect = 7e-04 Identities = 50/207 (24%), Positives = 81/207 (39%), Gaps = 16/207 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPD-ENISVAIESDMHMYC 692 P + KP + + L CR P+P+I WL G+ I +N S + D ++ Sbjct: 416 PYWLDKPTNLVLAPNENGRLVCRANGNPKPNIQWLINGQPIESSPQNPSRDVLGDTIIFR 475 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGES 751 SV Q G+ V N + + + PP+++ P +I V + Sbjct: 476 SV---------QMGSSAVYQCNASNQYGYLLSNAFVSVLDMPPRMLGPKNQLIKVIENNH 526 Query: 752 VILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSE 811 L G+P P + W KN + + +K + +DEG YT A + Sbjct: 527 TFLDCPFFGSPLPDLRWFKNGQGSGVDGGHYSVHNNGTLEIKRARSEDEGTYTCVASSLL 586 Query: 812 GIAETSAVITVEE-----PTEENAEPP 833 G AE + V+E P+ +A PP Sbjct: 587 GKAENQVRLEVKEEASLNPSVSSALPP 613 Score = 41.9 bits (94), Expect = 0.19 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 7/95 (7%) Query: 733 EPPQVI-EPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNK-----PVKALPTKSDGDT 786 +PP ++ + +K IV +++I+ + GNP P +W +N K + T+ D T Sbjct: 1 QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60 Query: 787 HSITILKPKKVKD-EGVYTLKAENSEGIAETSAVI 820 I K +D EG Y A N G+A ++ ++ Sbjct: 61 LEINFRSGGKQEDYEGEYQCFASNELGVALSNKIL 95 Score = 40.7 bits (91), Expect = 0.43 Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 3/76 (3%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 +C G P P + WF+ + S +Y N TL I+ ED GT+TCVA + Sbjct: 530 DCPFFGSPLPDLRWFKNG---QGSGVDGGHYSVHNNGTLEIKRARSEDEGTYTCVASSLL 586 Query: 590 GFASSTTELIVEAPLS 605 G A + L V+ S Sbjct: 587 GKAENQVRLEVKEEAS 602 Score = 39.9 bits (89), Expect = 0.75 Identities = 55/215 (25%), Positives = 84/215 (39%), Gaps = 21/215 (9%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQ---EGKKWKXXXXX-XXXXARIQKLSINTTYQFR 1838 SV +TW P N SP+ + V+ ++ E +W+ + I +L+ YQFR Sbjct: 631 SVRLTWIPGNDNR-SPVTHFLVQFEEDRWEPGRWRNLSSYPGHLNSVILQLAPFVNYQFR 689 Query: 1839 IYARNEIGTSLP-YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP----ESNG 1893 + A N +G S P S T G P PR S ++ + W EP E NG Sbjct: 690 VIAINSVGQSEPSLPSPQYKTSG--AAPDVIPRGLRGWGSMKGNMEITW-EPLLDLERNG 746 Query: 1894 GSPITNYIIEFKTV-KGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 + Y + +K + W + TV +H + N + +I A N G S P Sbjct: 747 AN--LYYSVWWKRKDTSEDWNNVTTVR---TKHVVHNTETYVPYQIKIQAGNEFG-SGPE 800 Query: 1953 ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSW 1987 + + T PT L + V +N W Sbjct: 801 SNIIIGYSGEDTPTDAPT-ELRVSRVDTNRAHIHW 834 Score = 38.3 bits (85), Expect = 2.3 Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 2/99 (2%) Query: 633 PPTFSKKPKAQY-VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT K+ Y VD +I++EC P PD +W G+ ++ VA + D Sbjct: 2 PPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGTL 61 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKT 729 + ++ EG Y A N G A S I+L++ + Sbjct: 62 EINFRSGGKQEDYEGEYQCFASNELGVALSNKILLRVSS 100 Score = 37.9 bits (84), Expect = 3.0 Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + EC G P P I W+R+ + P + ++ +++ N TL++ V EDAG + C Sbjct: 340 GQQLLLECIAAGVPTPTIKWYRKGGDL-PER--KVKFENFN-KTLLVVGVSEEDAGEYVC 395 Query: 584 VAKNAAG 590 +A N G Sbjct: 396 MAINHQG 402 Score = 37.5 bits (83), Expect = 4.0 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 4/87 (4%) Query: 831 EPPLFINR-FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEI--ISPSETITQNFDGEN 887 +PP + + ++ V + I + NPVP +W RN + + + D Sbjct: 1 QPPTIVKQSVKDYIVDPRDNIIIECEAKGNPVPDFSWRRNGKFFNLGKDPRVATQKDSGT 60 Query: 888 IELVITNVDSEID-SGDYKCVASNSAG 913 +E+ + + D G+Y+C ASN G Sbjct: 61 LEINFRSGGKQEDYEGEYQCFASNELG 87 Score = 36.7 bits (81), Expect = 7.0 Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 6/114 (5%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +L+ P K + V E + L+C P PD+ W G+ D ++ ++ Sbjct: 504 VLDMPPRMLGPKNQLIKVIENNHTFLDCPFFGSPLPDLRWFKNGQGSGVDGG-HYSVHNN 562 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL 741 L+I + EGTYT VA + G+A + L++K P V L Sbjct: 563 -----GTLEIKRARSEDEGTYTCVASSLLGKAENQVRLEVKEEASLNPSVSSAL 611 >UniRef50_Q4SCT9 Cluster: Chromosome 7 SCAF14650, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7 SCAF14650, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1450 Score = 92.3 bits (219), Expect = 1e-16 Identities = 89/284 (31%), Positives = 120/284 (42%), Gaps = 26/284 (9%) Query: 636 FSKKPKAQYVDEGSDILLECRLV-AIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 F + P V G +LEC+ PEP I+W G + D++ + I S Sbjct: 9 FRQNPVDVMVAVGEPAVLECQPPRGHPEPTISWRRDGANL-NDKDERITIRSGK------ 61 Query: 695 LKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVIL 754 L ITN KK G Y V N GE I + E P ++ +S++V ESV Sbjct: 62 LMITNTKKSDAGKYICVGTNMVGERESEIA---ELTVLERPTFVKRPRSVVVLAEESVKF 118 Query: 755 SAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIA 814 V G+P PT+ W K++ + D H++ I + V DEG YT EN G + Sbjct: 119 HCVVQGDPVPTVRWRKDDSDLPK-GRFEILDDHTLNIRQVTSV-DEGSYTCVVENMVGKS 176 Query: 815 ETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE--- 871 E SA +TV P P R QE V T + A T NP P+I W + Sbjct: 177 EASATLTVHVPPAFAVRP-----RNQEAAVGRIVTFQCEA--TGNPQPAIFWQKEGSESL 229 Query: 872 --IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 P + ++ + L ITNV DSG Y C A N AG Sbjct: 230 LFSYQPPQPFSRLSVSQTGSLTITNVQHS-DSGFYSCQALNIAG 272 Score = 66.9 bits (156), Expect = 6e-09 Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 17/212 (8%) Query: 744 MIVRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGV 802 ++V GE +L Q G+P PTI+W ++ + + + + I KK D G Sbjct: 16 VMVAVGEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKK-SDAGK 74 Query: 803 YTLKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPV 861 Y N G E+ A +TV E P F+ R + + V + ++K V +PV Sbjct: 75 YICVGTNMVGERESEIAELTV-------LERPTFVKRPRSVVVLAEESVKFHCVVQGDPV 127 Query: 862 PSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARV 921 P++ W +++ + + NI V + +D G Y CV N GKS A + Sbjct: 128 PTVRWRKDDSDLPKGRFEILDDHTLNIRQV-----TSVDEGSYTCVVENMVGKSEASATL 182 Query: 922 TIDVEKVTFVKHLQKSYETEEGKTVILECQTS 953 T+ V V+ ++ E G+ V +C+ + Sbjct: 183 TVHVPPAFAVR--PRNQEAAVGRIVTFQCEAT 212 Score = 63.3 bits (147), Expect = 7e-08 Identities = 74/295 (25%), Positives = 116/295 (39%), Gaps = 25/295 (8%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-----IIKPSQDFQMYYDDDN 564 P F + R + G V F+C+ G P+P I W ++ + +P Q F Sbjct: 188 PAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRL-SVSQ 246 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLS-------DHGSEMTVXXXX 617 +L I V D+G ++C A N AG S T+ ++E S + + Sbjct: 247 TGSLTITNVQHSDSGFYSCQALNIAG--SVITKALLEVTDSYFLQAWRKYAAAFFPHWPW 304 Query: 618 XXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP- 676 + + PP + P Q V S ++L C V IP P I W G + P Sbjct: 305 LWFAESHHSAGADHPPPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPA 364 Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 D +S+ +DM L+I K G+YT VA + GEAS L+++ G Sbjct: 365 DSRMSI---TDM----GSLEIRYAKLGDTGSYTCVATSPNGEASWTAHLQVE-GRVWSCC 416 Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI 791 + P + + G + +TW K+N+ A PT + S T+ Sbjct: 417 SLRPPADLNLIPGAPSKPEVTDITRTSVMLTW-KSNQSSGAAPTSYLIEAFSYTL 470 Score = 60.9 bits (141), Expect = 4e-07 Identities = 41/198 (20%), Positives = 79/198 (39%), Gaps = 7/198 (3%) Query: 1472 KVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYEN 1531 ++ + T ++ PT K +++ E ++ C+ G P P V W +D L + + Sbjct: 89 EIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDLPKGRFEILD 148 Query: 1532 RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWL 1591 Y C+ N G+ E S + + P + + Q+ VG Sbjct: 149 DHTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFAVRPRN--QEAAVGRIVT 206 Query: 1592 VTAVIEGIPPPEVIWYKNGNK-----LENDKEYNITTKEKTSVIRIKELKRSHSSKYTIE 1646 G P P + W K G++ + + ++ + +T + I ++ S S Y+ + Sbjct: 207 FQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLTITNVQHSDSGFYSCQ 266 Query: 1647 ASNTAGTSSVEVTLKVYD 1664 A N AG+ + L+V D Sbjct: 267 ALNIAGSVITKALLEVTD 284 Score = 60.1 bits (139), Expect = 7e-07 Identities = 57/235 (24%), Positives = 87/235 (37%), Gaps = 21/235 (8%) Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 +I SD G + V A++ PTF K+P++ V + C + Sbjct: 63 MITNTKKSDAGKYICVGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVV 122 Query: 658 VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG 717 P P + W K + +P + D H L I V EG+YT V N G Sbjct: 123 QGDPVPTVRWR-KDDSDLPKGRFEIL---DDH----TLNIRQVTSVDEGSYTCVVENMVG 174 Query: 718 EASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN----- 772 ++ L + PP ++ G V + GNP+P I W K Sbjct: 175 KSEASATLTVHV----PPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLL 230 Query: 773 ---KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEE 824 +P + S T S+TI + D G Y+ +A N G T A++ V + Sbjct: 231 FSYQPPQPFSRLSVSQTGSLTITNVQH-SDSGFYSCQALNIAGSVITKALLEVTD 284 Score = 58.4 bits (135), Expect = 2e-06 Identities = 65/273 (23%), Positives = 110/273 (40%), Gaps = 23/273 (8%) Query: 1121 GNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC 1178 G A E + +G + + W +DG+ + + ++TI + KL I + DAG+Y C Sbjct: 21 GEPAVLECQPPRGHPEPTISWRRDGANLNDKDE-RITI--RSGKLMITNTKKSDAGKYIC 77 Query: 1179 EVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKK 1232 N S+ + +E P+ F R +++ + + V D V W K Sbjct: 78 VGTNMVGERESEIAELTVLERPT--FVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKD 135 Query: 1233 KSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIV 1291 S + +F ++ D TL IR+ T D+ YTCV+ + ++ + V PP Sbjct: 136 DSDLPKG-RFEILDD---HTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFA 191 Query: 1292 DYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK-----SASLT 1346 R G VT + PQP W + P S+ + SLT Sbjct: 192 VRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVSQTGSLT 251 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILD 1379 I V+++D+G Y + N G + + + D Sbjct: 252 ITNVQHSDSGFYSCQALNIAGSVITKALLEVTD 284 Score = 55.2 bits (127), Expect = 2e-05 Identities = 60/258 (23%), Positives = 106/258 (41%), Gaps = 27/258 (10%) Query: 943 GKTVILECQT--SHTVST-KWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC 999 G+ +LECQ H T W + ++ D R I+ G+ D G C Sbjct: 21 GEPAVLECQPPRGHPEPTISWRRDGANLNDKDERITIRSGKLMITNTKKS---DAGKYIC 77 Query: 1000 I----VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGE 1054 + V ++E+ + P F+++ + V ++ + + V W +D Sbjct: 78 VGTNMVGERESEIAELTVLERPTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDS 137 Query: 1055 IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD---ESCTAEVTVVELPPEIIT 1111 + K +++ L IR + DEG Y+C++ + +S + V +PP Sbjct: 138 DLP--KGRFEILDD---HTLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPAFAV 192 Query: 1112 RLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSE-IQFSNH-----IQLTIDGKKQKLK 1164 R +NQ+ G TF+ E T + W K+GSE + FS +L++ + L Sbjct: 193 RPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSV-SQTGSLT 251 Query: 1165 IYDCDLDDAGEYSCEVGN 1182 I + D+G YSC+ N Sbjct: 252 ITNVQHSDSGFYSCQALN 269 Score = 51.6 bits (118), Expect = 2e-04 Identities = 31/94 (32%), Positives = 50/94 (53%), Gaps = 5/94 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV++ R +V+F C V+G P P + W + + + P F++ DD+ TL Sbjct: 99 PTFVKRPRSVVVLAEESVKFHCVVQGDPVPTVRWRKDDSDL-PKGRFEIL--DDH--TLN 153 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 IR+V D G++TCV +N G + ++ L V P Sbjct: 154 IRQVTSVDEGSYTCVVENMVGKSEASATLTVHVP 187 Score = 51.2 bits (117), Expect = 3e-04 Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 1/90 (1%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI 1440 P P KP + +I +S+ + W +++G + Y + + + W+++ KT T + Sbjct: 428 PGAPSKPEVTDITRTSVMLTWKSNQSSGAAPTSYLIEAFSYTLGSRWVTLVEHVKTDTFV 487 Query: 1441 -QNLKTNSSYRFRAYAVNEVDISDASETTE 1469 +NL+ + Y F AVN ISD S T+ Sbjct: 488 LKNLRPATVYLFMVRAVNSHGISDPSPITD 517 Score = 46.4 bits (105), Expect = 0.009 Identities = 73/274 (26%), Positives = 105/274 (38%), Gaps = 44/274 (16%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIV--------PDENISVA 683 +PP F+ +P+ Q G + +C P+P I W +G E + P +SV+ Sbjct: 186 VPPAFAVRPRNQEAAVGRIVTFQCEATGNPQPAIFWQKEGSESLLFSYQPPQPFSRLSVS 245 Query: 684 I----------ESDMHMY-CSVLKITN---VKKFQEGT--YTVVAVNREGEASLP----- 722 SD Y C L I K E T Y + A + A P Sbjct: 246 QTGSLTITNVQHSDSGFYSCQALNIAGSVITKALLEVTDSYFLQAWRKYAAAFFPHWPWL 305 Query: 723 --IVLKIKTGEKEPPQVIE--PLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKAL 778 G PP VI+ PL + V +V+LS VG P P I W K+ + Sbjct: 306 WFAESHHSAGADHPPPVIKRGPL-NQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPA 364 Query: 779 PTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE--NAEPPLF 835 ++ S D S+ I + K+ D G YT A + G A +A + VE + PP Sbjct: 365 DSRMSITDMGSLEI-RYAKLGDTGSYTCVATSPNGEASWTAHLQVEGRVWSCCSLRPPAD 423 Query: 836 INRFQEITVKEKGTIKLVARVTRNPVPSITWYRN 869 +N K + V +TR V +TW N Sbjct: 424 LNLIPGAPSKPE-----VTDITRTSV-MLTWKSN 451 Score = 45.2 bits (102), Expect = 0.020 Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVHE 1924 P P V++ T SV L W +S+G +P T+Y+IE F G W +V Sbjct: 428 PGAPSKPEVTDITRTSVMLTWKSNQSSGAAP-TSYLIEAFSYTLGSRWVTLVE-HVKTDT 485 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRL-EKHATVP 1966 ++N++ +F + A N+ G+S P+ + SVR + +T+P Sbjct: 486 FVLKNLRPATVYLFMVRAVNSHGISDPSPITDSVRTQDSPSTIP 529 Score = 40.7 bits (91), Expect = 0.43 Identities = 36/164 (21%), Positives = 63/164 (38%), Gaps = 10/164 (6%) Query: 1507 GVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G P+P ++W RDG L K + T + Y C+ N GE E+ Sbjct: 33 GHPEPTISWRRDGANLNDKDERITIRS-GKLMITNTKKSDAGKYICVGTNMVGERESEIA 91 Query: 1565 -VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + + ++P + + ++ V++G P P V W K+ + L + + I Sbjct: 92 ELTVLERPTFVKRPRSVVVLAEESVKF--HCVVQGDPVPTVRWRKDDSDLPKGR-FEILD 148 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS 1667 + I+++ YT N G S TL V+ P+ Sbjct: 149 DH---TLNIRQVTSVDEGSYTCVVENMVGKSEASATLTVHVPPA 189 Score = 38.7 bits (86), Expect = 1.7 Identities = 23/93 (24%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Query: 832 PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELV 891 PP+ TV T+ L P P I W ++ ++SP+++ D ++E+ Sbjct: 320 PPVIKRGPLNQTVPVDSTVVLSCHAVGIPPPVIHWKKDGVVLSPADSRMSITDMGSLEIR 379 Query: 892 ITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 + D+G Y CVA++ G++S A + ++ Sbjct: 380 YAKLG---DTGSYTCVATSPNGEASWTAHLQVE 409 >UniRef50_Q9UMZ3 Cluster: Phosphotidylinositol phosphatase PTPRQ precursor; n=14; Amniota|Rep: Phosphotidylinositol phosphatase PTPRQ precursor - Homo sapiens (Human) Length = 2332 Score = 92.3 bits (219), Expect = 1e-16 Identities = 86/355 (24%), Positives = 143/355 (40%), Gaps = 17/355 (4%) Query: 1676 REISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENC 1735 + IS S+ + W PP G ++T Y I E D NR ++ +D ++ I L + Sbjct: 620 KNISSSSILLYWDPPEYPNG-KITHYTIYAMELDTNRAFQITTIDN---SFLITGLKKYT 675 Query: 1736 EYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNG 1795 +Y RV A VG S E I ++T+ D P + + + + W P EK Sbjct: 676 KYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKPN 735 Query: 1796 GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDD 1855 G II Y+V K + R L +T Y + + G +S Sbjct: 736 GI-IIAYEVLYKNIDTLYMKNTSTTDIILR--NLRPHTLYNISVRSYTRFGHGNQVSSLL 792 Query: 1856 KITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKI 1915 + +T+ P S P N +S + L + P S G I Y I K G I Sbjct: 793 SVRTSETV-PDSAPENITYKNISSGEIELSFLPPSSPNGI-IKKYTIYLKRSNGNEERTI 850 Query: 1916 VTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEI 1975 T S+ ++ I+ +K+ + I +SA G + + S+ E+ A P P + Sbjct: 851 NTT--SLTQN-IKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDA--PDSPPQDFSV 905 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAI--RDVTKTMWMEVGKVDVNTLKFNI 2028 + + V SW P G +L Y + + R KT+ + ++++ L +N+ Sbjct: 906 KQLSGVTVKLSWQPPLEPNGI-ILYYTVYVWNRSSLKTINVTETSLELSDLDYNV 959 Score = 78.6 bits (185), Expect = 2e-12 Identities = 126/636 (19%), Positives = 229/636 (36%), Gaps = 39/636 (6%) Query: 1388 NILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNS 1447 N I SSSI + WD PE N I +Y + E+DT + I + I LK + Sbjct: 618 NYKNISSSSILLYWDPPEYP-NGKITHYTIYAMELDTNRAFQITTIDNSFL-ITGLKKYT 675 Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 Y+ R A V S SE + + E + +S + + ++T + +I L Sbjct: 676 KYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTAD---EIRLKWSPPE 732 Query: 1508 VPQPKVTWYRD-GKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 P + Y K + T K T + HG +S + Sbjct: 733 KPNGIIIAYEVLYKNIDTLYMKNTSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLL 792 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDE----WLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + V + E+I K+ E +L + GI I+ K N ++E Sbjct: 793 SVRTSETVPDSAPENITYKNISSGEIELSFLPPSSPNGIIKKYTIYLKRSN---GNEERT 849 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT-LKVYDKPSKPEGPVIMREIS 1679 I T T I++ + + + + G S ++ L D P P ++++S Sbjct: 850 INTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLS 909 Query: 1680 RESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMF 1739 +V + W+PPL+ G+ + Y + + + I V + + + L+ N EY Sbjct: 910 GVTVKLSWQPPLEPNGI-ILYYTVYVWNRSSLKTINVTETSLE-----LSDLDYNVEYSA 963 Query: 1740 RVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPI 1799 V A G + S I +T PS + + S+ + W P K G I Sbjct: 964 YVTASTRFGDGKT-RSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGI-I 1021 Query: 1800 IDYKVEIKQEGKKWKXXXX---------XXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 Y V + + I KL+I + Y F + A +G Sbjct: 1022 QYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNK 1081 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGK 1910 + ++ + + P N +S ++ + W P G + + Sbjct: 1082 SSDIIEVYTDQDI-PEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRH 1140 Query: 1911 SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPT 1970 +VT S++ +N+++ + I +I+ G S T + + ++ VP Sbjct: 1141 VRPPLVTYERSIY---FDNLEKYTDYILKITPSTEKGFS-DTYTAQLYIKTEEDVPETSP 1196 Query: 1971 APLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIR 2006 + + S V+ SW P GA ++ Y++ ++ Sbjct: 1197 IINTFKNLSSTSVLLSWDPPVKPNGA-IISYDLTLQ 1231 Score = 59.3 bits (137), Expect = 1e-06 Identities = 81/354 (22%), Positives = 135/354 (38%), Gaps = 34/354 (9%) Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKP-PLDDGGLELTKYAIEKHEPDN 1710 G SS+ P P + + + + V ++W P PL G +++ + I +HE D Sbjct: 1270 GPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDT 1329 Query: 1711 NRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 + ++ + + ++ ++ Y RV A VG S + T VP Sbjct: 1330 IYYKNISGFKTEAKLVGLEPVST---YSIRVSAFTKVGNGNQF-SNVVKFTTQESVPDVV 1385 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLS 1830 +SV + W P +K G I Y V +++ K KL Sbjct: 1386 QNMQCMAT-SWQSVLVKWDPPKKANGI-ITQYMVTVERNSTKVSPQDHMYTFI----KLL 1439 Query: 1831 INTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPE 1890 NT+Y F++ A G T T+ +T+ PS P N S+ S S TL W P+ Sbjct: 1440 ANTSYVFKVRASTSAGEGDESTCHVS-TLPETV--PSVPTNIAFSDVQSTSATLTWIRPD 1496 Query: 1891 SNGGSPITNYII--EFKTVKGKSWTKIVTV---------GGSVHEHCIENIKEKDEIIFR 1939 + G NY I + + K K W V + E + +K+ F+ Sbjct: 1497 TILGY-FQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQ 1555 Query: 1940 ISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLE-IRMVGSN--IVMTSWGTP 1990 ++A G + S + T+P PP P E + +V ++ + SW P Sbjct: 1556 VAASTNAGYGNASNWISTK-----TLPGPPDGPPENVHVVATSPFSISISWSEP 1604 Score = 52.4 bits (120), Expect = 1e-04 Identities = 75/406 (18%), Positives = 156/406 (38%), Gaps = 27/406 (6%) Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY-----DKP 1666 +L+ ++ + ITT + + +I LK+ K + AS G SS+ ++ D+P Sbjct: 650 ELDTNRAFQITTIDNSFLIT--GLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEP 707 Query: 1667 SKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETY 1726 V + +++ + + ++W PP G+ + + K+ + ++K + Sbjct: 708 ESSPQDVEVIDVTADEIRLKWSPPEKPNGIIIAYEVLYKN--IDTLYMK----NTSTTDI 761 Query: 1727 CIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYI 1786 ++ L + Y V + G + S + ++T+ VP I + + + Sbjct: 762 ILRNLRPHTLYNISVRSYTRFGHGNQV-SSLLSVRTSETVPDSAPENITYKNISSGEIEL 820 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 ++ P G I Y + +K+ + I+ L T Y + A G Sbjct: 821 SFLPPSSPNGI-IKKYTIYLKRSNGNEERTINTTSLTQNIKVLKKYTQYIIEVSASTLKG 879 Query: 1847 TSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP-ESNGGSPITNYIIEFK 1905 + +T + P S P++F V + + +V L W P E NG II + Sbjct: 880 EGVRSAPISILT--EEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEPNG-------IILYY 930 Query: 1906 TVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATV 1965 TV + + + T+ + + ++ E ++A G T S + + Sbjct: 931 TVYVWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDG-KTRSNIISFQTPEGA 989 Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT 2011 PS P + + S+ ++ W P G + Y++ R+ + T Sbjct: 990 PSDPPKDVYYANLSSSSIILFWTPPSKPNGI-IQYYSVYYRNTSGT 1034 Score = 36.3 bits (80), Expect = 9.2 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 5/95 (5%) Query: 1376 TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEWISVKN 1432 T + KP PP + S+ I + W+ P N N II Y+V+Y+E+ T + V++ Sbjct: 93 TNVTKPGPPVFLAGERVGSAGILLSWNTPPNP-NGRIISYIVKYKEVCPWMQTVYTQVRS 151 Query: 1433 ITKT-QTSIQNLKTNSSYRFRAYAVNEVDISDASE 1466 + + + NL ++Y + A N I S+ Sbjct: 152 KPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSD 186 >UniRef50_UPI00015B59DF Cluster: PREDICTED: similar to turtle protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to turtle protein - Nasonia vitripennis Length = 1402 Score = 91.5 bits (217), Expect = 2e-16 Identities = 92/401 (22%), Positives = 159/401 (39%), Gaps = 38/401 (9%) Query: 633 PPTFSKKPKAQ-YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PP F+ P+ YV+ G I+L C+ P P+I W + P +++ + Sbjct: 309 PPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG----- 363 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 + L+I+ +K G YT +A N EG+ S + I G + P ++ +GE+ Sbjct: 364 -TELRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGG----AVITIPPQNETKLEGEN 418 Query: 752 VILSAQVVGNP-RPTITWCKNNKP---VKALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V+ + P T++W + P V L T++ + P D G Y Sbjct: 419 VVFPCEAKALPGNVTVSWYREGAPISEVSELDTRASVRMDGSLAINPVSADDSGTYLCTV 478 Query: 808 ENSEGIAET-SAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW 866 N G +T SA + VE P + P + Q + + G ++ + P+ +TW Sbjct: 479 SNGIGEPQTASAYLNVEYPAKVTFNPTV-----QYLPFRMAGVVQCYIK-ANPPLQYVTW 532 Query: 867 YRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG-KSSHGARVTIDV 925 ++ ++ P + G N L+ T V +E G Y C N+ G + S G + Sbjct: 533 TKDKRLLEPYQVKDIVVMG-NGSLLFTRV-NENHHGQYTCTPYNAHGTQGSSGYMEVLVR 590 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTVSTK-----WYHNKKEISGMDHREIIQEGR 980 F Q Y+ + G+TV + C + T+ W E +++ Sbjct: 591 NPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRAKVV---- 646 Query: 981 XXXXXXXXXXXXDVGVIKCIVKDQET----STMLVVKETIP 1017 D GV +C+V ++ ST L+V+ T P Sbjct: 647 GGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIVEGTQP 687 Score = 80.6 bits (190), Expect = 4e-13 Identities = 102/455 (22%), Positives = 186/455 (40%), Gaps = 45/455 (9%) Query: 1032 DVAILEVEIN-SETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCI 1090 D IL + + T +++W +D ++P +R I D G+Y+C+ Sbjct: 326 DAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDGTELR---ISTIKTEDIGDYTCL 382 Query: 1091 LRDE----SCTAEV-----TVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFK 1141 R+ S TA V V+ +PP+ T+L+ + V E + G+ V W++ Sbjct: 383 ARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENV----VFPCEAKALPGNVTVSWYR 438 Query: 1142 DGSEIQFSNHIQLTIDGKKQ-KLKIYDCDLDDAGEYSCEVGN-----SKCTAILTVEEP- 1194 +G+ I + + + L I DD+G Y C V N +A L VE P Sbjct: 439 EGAPISEVSELDTRASVRMDGSLAINPVSADDSGTYLCTVSNGIGEPQTASAYLNVEYPA 498 Query: 1195 --SINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRT 1252 + N T++ F + Y+ P + VTW K K ++E + ++ + + Sbjct: 499 KVTFNPTVQYLPFRMAGV-VQCYIKANPPLQY--VTWTKDKRLLEPYQVKDIVV-MGNGS 554 Query: 1253 LIIRKCTEDDQCEYTCVLLDAKST--TKLKVEV-VEFPPKI-VDYEREYRIKRGSDVTL- 1307 L+ + E+ +YTC +A T + +EV V PP V+ + Y+ K G V + Sbjct: 555 LLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEVLVRNPPVFTVEPQPMYQRKVGETVEMH 614 Query: 1308 --LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN 1365 + +P W K ++ + + +LTI+ ++ D G+Y+ + N Sbjct: 615 CAAQESSGTQKPTVTW--QRKDGEELARGRAKV--VGGNLTIENLKQQDFGVYECVVSNE 670 Query: 1366 CGHADVEMNVTILDKPSPPGKPNILEI-DSSSINICWDEPENTGNSTIIYYVVEYQEIDT 1424 V+ I++ P N+ + D S+ + W + G Y + ++E Sbjct: 671 VA-TIVKSTHLIVEGTQPHAPHNVTGVADQFSVTLSWQPGYSGGPDYKQDYTIWHREEGA 729 Query: 1425 TEW--ISVKNITKTQTSIQNLKTNSSYRFRAYAVN 1457 EW I V T +I LK+ +++ F+ N Sbjct: 730 QEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGKN 764 Score = 74.1 bits (174), Expect = 4e-11 Identities = 75/272 (27%), Positives = 112/272 (41%), Gaps = 24/272 (8%) Query: 832 PPLFINRFQEITVKEKG-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIEL 890 PP F +E+ G I L + P P I WY++ + PS T+T DG EL Sbjct: 309 PPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG--TEL 366 Query: 891 VITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETE-EGKTVILE 949 I+ + +E D GDY C+A N G+ SH ARV I V + ET+ EG+ V+ Sbjct: 367 RISTIKTE-DIGDYTCLARNGEGQISHTARVIIAGGAVITI---PPQNETKLEGENVVFP 422 Query: 950 CQTS---HTVSTKWYHNK---KEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKD 1003 C+ V+ WY E+S +D R ++ D G C V + Sbjct: 423 CEAKALPGNVTVSWYREGAPISEVSELDTRASVR--MDGSLAINPVSADDSGTYLCTVSN 480 Query: 1004 -----QETSTMLVVKETIP-EFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIK 1057 Q S L V+ F +Q + V ++ N V W +D +++ Sbjct: 481 GIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANPPLQYVTWTKDKRLLE 540 Query: 1058 PKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 P + K D G+ L+ R H G+Y+C Sbjct: 541 PYQVK-DIVVMGNGSLLFTRVNENH-HGQYTC 570 Score = 64.1 bits (149), Expect = 4e-08 Identities = 70/243 (28%), Positives = 105/243 (43%), Gaps = 16/243 (6%) Query: 695 LKITNVKKFQEGTYT--VVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 L +TN+++ +G Y VV +NR + P I P + + V G+++ Sbjct: 269 LNLTNIQESDQGWYECKVVFLNRSPNNNKNGTWFHLDVHAPPRFTITPEEMIYVNLGDAI 328 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEG 812 IL+ Q G P P I W K+ PV+ T + + + + K +D G YT A N EG Sbjct: 329 ILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDGTELRISTIKTEDIGDYTCLARNGEG 388 Query: 813 -IAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 I+ T+ VI PP + + E A+ V +++WYR Sbjct: 389 QISHTARVIIAGGAV--ITIPPQNETKLE----GENVVFPCEAKALPGNV-TVSWYREGA 441 Query: 872 IISP-SETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVE---K 927 IS SE T+ + L I V ++ DSG Y C SN G+ A ++VE K Sbjct: 442 PISEVSELDTRASVRMDGSLAINPVSAD-DSGTYLCTVSNGIGE-PQTASAYLNVEYPAK 499 Query: 928 VTF 930 VTF Sbjct: 500 VTF 502 Score = 60.1 bits (139), Expect = 7e-07 Identities = 96/404 (23%), Positives = 154/404 (38%), Gaps = 59/404 (14%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G + CQ EG P P+I W++ ++PS + D L I + ED G +TC Sbjct: 325 GDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIINDG---TELRISTIKTEDIGDYTC 381 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 +A+N G S T +I+ G+ +T IPP K Sbjct: 382 LARNGEGQISHTARVIIAG-----GAVIT-------------------IPPQNETKL--- 414 Query: 644 YVDEGSDILLECRLVAIP-EPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKK 702 EG +++ C A+P ++W +G I E + + + M S L I V Sbjct: 415 ---EGENVVFPCEAKALPGNVTVSWYREGAPI--SEVSELDTRASVRMDGS-LAINPVSA 468 Query: 703 FQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV-IEPLKSMIVRQGESVILSAQVVGN 761 GTY N GE P + P +V P + + V+ Sbjct: 469 DDSGTYLCTVSNGIGE---PQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKANP 525 Query: 762 PRPTITWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTLKAENSEGIAETSAV- 819 P +TW K+ + ++ K + ++L + G YT N+ G +S Sbjct: 526 PLQYVTWTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQYTCTPYNAHGTQGSSGYM 585 Query: 820 -ITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR-NNEIISPS 876 + V P EP P++ + E TV+ + + + P++TW R + E ++ Sbjct: 586 EVLVRNPPVFTVEPQPMYQRKVGE-TVEMHCAAQESSGTQK---PTVTWQRKDGEELARG 641 Query: 877 ETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG---KSSH 917 G N L I N+ + D G Y+CV SN KS+H Sbjct: 642 RA---KVVGGN--LTIENLKQQ-DFGVYECVVSNEVATIVKSTH 679 Score = 56.4 bits (130), Expect = 8e-06 Identities = 100/498 (20%), Positives = 177/498 (35%), Gaps = 43/498 (8%) Query: 1284 VEFPPKI-VDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKS 1342 V PP+ + E + G + L + P P W ++ ++ +I + Sbjct: 306 VHAPPRFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTV--TIINDG 363 Query: 1343 ASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINICW 1401 L I ++ D G Y N G V I P N +++ ++ Sbjct: 364 TELRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENVVFPC 423 Query: 1402 DEPENTGNSTIIYY-----VVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAV 1456 + GN T+ +Y + E E+DT + + +I + + S + Sbjct: 424 EAKALPGNVTVSWYREGAPISEVSELDTRASVRMDG----SLAINPVSADDSGTYLCTVS 479 Query: 1457 NEVDISDASETTEYYKVIKETKIQ-SPTVEK-PLKNITTEPNEDIELTCIFGGVPQPKVT 1514 N I + + Y V K+ +PTV+ P + + I P VT Sbjct: 480 N--GIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMA------GVVQCYIKANPPLQYVT 531 Query: 1515 WYRDGKKLKTAKA---TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS--CVVGIQQ 1569 W +D + L+ + Y C +N HG +S V ++ Sbjct: 532 WTKDKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQYTCTPYNAHGTQGSSGYMEVLVRN 591 Query: 1570 KPVITISNEDIKQKHKVGDEWLVTAVIE---GIPPPEVIWY-KNGNKLENDKEYNITTKE 1625 PV T+ + + Q+ KVG+ + + G P V W K+G +L + K Sbjct: 592 PPVFTVEPQPMYQR-KVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGR-----AKV 645 Query: 1626 KTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRE-SVT 1684 + I+ LK+ Y SN T L V + ++P P + ++ + SVT Sbjct: 646 VGGNLTIENLKQQDFGVYECVVSNEVATIVKSTHLIV--EGTQPHAPHNVTGVADQFSVT 703 Query: 1685 IEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQ 1744 + W+P G Y I E W + T I +L + F+V+ + Sbjct: 704 LSWQPGYSGGPDYKQDYTIWHREEGAQEWKTIPVTPSGSTTVTISRLKSGTNHEFQVVGK 763 Query: 1745 NPVGFSEALESEPIVIKT 1762 N +G + + S I ++T Sbjct: 764 NALG--DGMSSGIITVRT 779 Score = 42.3 bits (95), Expect = 0.14 Identities = 75/354 (21%), Positives = 134/354 (37%), Gaps = 29/354 (8%) Query: 1189 LTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDE-TLDVTWYKKKSVIEDTEKFTLISD 1247 L V P FT+ E I V L + T ++ WYK + +E + T+I+D Sbjct: 304 LDVHAPP-RFTITPEEMIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSSTVTIIND 362 Query: 1248 VKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIK-RGSDVT 1306 + L I +D +YTC+ + + V+ ++ + K G +V Sbjct: 363 GTE--LRISTIKTEDIGDYTCLARNGEGQISHTARVIIAGGAVITIPPQNETKLEGENVV 420 Query: 1307 LLVDYQAFP-QPNDEWIVNSKIIKKCKH--TKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 + +A P W I + T+ S+ SL I V D+G Y + Sbjct: 421 FPCEAKALPGNVTVSWYREGAPISEVSELDTRASV-RMDGSLAINPVSADDSGTYLCTVS 479 Query: 1364 NNCGH---ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 N G A +NV K + L + + C+ + + + YV + Sbjct: 480 NGIGEPQTASAYLNVEYPAKVTFNPTVQYLPFRMAGVVQCYIKA-----NPPLQYVTWTK 534 Query: 1421 EIDTTEWISVKNI-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKI 1479 + E VK+I S+ + N ++ + Y + ++ Y +V+ + Sbjct: 535 DKRLLEPYQVKDIVVMGNGSLLFTRVNENHHGQ-YTCTPYNAHGTQGSSGYMEVL----V 589 Query: 1480 QSPTV--EKPLKNITTEPNEDIELTCI---FGGVPQPKVTWYR-DGKKLKTAKA 1527 ++P V +P + E +E+ C G +P VTW R DG++L +A Sbjct: 590 RNPPVFTVEPQPMYQRKVGETVEMHCAAQESSGTQKPTVTWQRKDGEELARGRA 643 Score = 37.5 bits (83), Expect = 4.0 Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 2/83 (2%) Query: 523 DGSTVQFECQVEGYP-RPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 +G V F C+ + P ++W+R+ A I + +L I V +D+GT+ Sbjct: 415 EGENVVFPCEAKALPGNVTVSWYREGAPISEVSELDTRASVRMDGSLAINPVSADDSGTY 474 Query: 582 TCVAKNAAGF-ASSTTELIVEAP 603 C N G +++ L VE P Sbjct: 475 LCTVSNGIGEPQTASAYLNVEYP 497 >UniRef50_UPI0000D9D1DB Cluster: PREDICTED: similar to obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; n=1; Macaca mulatta|Rep: PREDICTED: similar to obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF - Macaca mulatta Length = 381 Score = 91.5 bits (217), Expect = 2e-16 Identities = 57/184 (30%), Positives = 91/184 (49%), Gaps = 3/184 (1%) Query: 1009 MLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKR 1068 M+V+ + +R L+D V E A ++E++ E W R G + P K Sbjct: 1 MVVIARQL-RVLRPLEDVTVSEGGSATFQLELSQEGVTGEWARGGVRLHPGP-KCHIHSE 58 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTVVELPPEIITRLQNQKVNKGNKATFEI 1128 GH +L ++ + D G S C A + V E+P I+ Q+ +V +G+ AT E Sbjct: 59 GHSHRLVLKGLGLADSGCVSFTADSLRCAARLVVREVPVTIVQGPQDLEVTEGDTATLEC 118 Query: 1129 ELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAI 1188 EL++ A V W KDG+ + S ++L G ++ L++ C DAG YSC VG ++ + Sbjct: 119 ELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCSPSDAGTYSCAVGTTRAGPV 178 Query: 1189 -LTV 1191 LTV Sbjct: 179 RLTV 182 Score = 66.5 bits (155), Expect = 8e-09 Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 1/171 (0%) Query: 1100 VTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGK 1159 + V+ ++ L++ V++G ATF++EL++ W + G + + +G Sbjct: 1 MVVIARQLRVLRPLEDVTVSEGGSATFQLELSQEGVTGEWARGGVRLHPGPKCHIHSEGH 60 Query: 1160 KQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVE 1219 +L + L D+G S + +C A L V E + ++ P+ + V A L E Sbjct: 61 SHRLVLKGLGLADSGCVSFTADSLRCAARLVVREVPVTI-VQGPQDLEVTEGDTATLECE 119 Query: 1220 IPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVL 1270 + DVTW K + + + + L + +R L +R+C+ D Y+C + Sbjct: 120 LSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCSPSDAGTYSCAV 170 Score = 63.7 bits (148), Expect = 5e-08 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 2/149 (1%) Query: 942 EGKTVILECQTSHT-VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCI 1000 EG + + + S V+ +W + I EG D G + Sbjct: 21 EGGSATFQLELSQEGVTGEWARGGVRLHPGPKCHIHSEGHSHRLVLKGLGLADSGCVSFT 80 Query: 1001 VKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWERDGEIIKPKK 1060 + LVV+E ++ QD EV E D A LE E++ ADV WE+DG + P Sbjct: 81 ADSLRCAARLVVREVPVTIVQGPQDLEVTEGDTATLECELSQALADVTWEKDGNALTPSP 140 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSC 1089 + + G R L +R S D G YSC Sbjct: 141 -RLRLQALGTRRLLQLRRCSPSDAGTYSC 168 Score = 48.0 bits (109), Expect = 0.003 Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 1/171 (0%) Query: 1113 LQNQKVNKGNKATFEIEL-TKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 LQ ++ + + T+ + T VR G ++ +++ +GKK L + + + Sbjct: 153 LQLRRCSPSDAGTYSCAVGTTRAGPVRLTVRGRPLRPGARVRIRQEGKKHILVLSELRAE 212 Query: 1172 DAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWYK 1231 DAGE + G ++ A+L VE + P V A L V + V W + Sbjct: 213 DAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLMGRRAVLEVTVSRSGSHVCWLR 272 Query: 1232 KKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVE 1282 + + + +K+ + S +L+I +DQ Y C + T+L VE Sbjct: 273 EGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSAHTRLLVE 323 Score = 38.7 bits (86), Expect = 1.7 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRD 1093 A+LEV ++ + V W R+G + P +KY+ G L I + D+G Y C Sbjct: 255 AVLEVTVSRSGSHVCWLREGAELCPG-DKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQ 313 Query: 1094 ESCTAEVTV 1102 +S + V Sbjct: 314 DSAHTRLLV 322 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 5/62 (8%) Query: 541 ITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIV 600 + W R+ A + P ++M +LVI +V PED GT+ C AG S+ T L+V Sbjct: 268 VCWLREGAELCPGDKYEMR-SHGPTHSLVIHDVRPEDQGTYCC----QAGQDSAHTRLLV 322 Query: 601 EA 602 EA Sbjct: 323 EA 324 >UniRef50_Q4RVM2 Cluster: Chromosome 9 SCAF14991, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9 SCAF14991, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1049 Score = 91.1 bits (216), Expect = 3e-16 Identities = 142/643 (22%), Positives = 250/643 (38%), Gaps = 62/643 (9%) Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W N +I+ + G N L+I+++D D G Y+C+A N+AG + R ++ Sbjct: 92 WSLNGTLINLGLDRRRRLSGGN--LIISSLDRYQDVGMYQCMAFNTAG-AILSRRASLQF 148 Query: 926 EKVTFVK-HLQKSYETEEGKTVILECQT---SHTVSTKWYHNKKE-ISGMDHREIIQEGR 980 + K H + + EG+ V+L C T S ++ W N+ D+R + + + Sbjct: 149 AYLDHFKVHTRSAVSVREGQGVVLLCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQ-Q 207 Query: 981 XXXXXXXXXXXXDVGVIKCIV-------KDQETSTMLVVKET--IPEFIRKLQ-----DF 1026 DVG C+V K Q + T L+++ + E+ K++ + Sbjct: 208 TGNLYIAKVEPSDVGNYTCVVTNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNV 267 Query: 1027 EVKEKDVAILEV-EINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEG 1085 LE + + ++ W+R + P K K + L I + D G Sbjct: 268 SAARGSTVTLECFALGNPVPEITWKRANGVPFPSKVKMKYSNA----VLEIPSFQQDDTG 323 Query: 1086 EYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFK 1141 Y C+ + T P+ I +++ + + +E K W K Sbjct: 324 GYECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEERLHWECRANGKPKPSYAWLK 383 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSI----- 1196 +G ++ + I + DG L + L DAG Y C V +K I V E + Sbjct: 384 NGQQLLSGDRITVE-DGV---LSVPALALSDAGMYQC-VAENKHGVIYFVAELMVLASPP 438 Query: 1197 NFTLRLPEFILVPANTDAYLTVEIPDETLDVT---WYKKKSVIEDTEKFTLISDVKKRTL 1253 +FT L +L A +T+E + V W K I ++ TL SD TL Sbjct: 439 DFTGNLLRALL-KAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSD---GTL 494 Query: 1254 IIRKCTEDDQCEYTCVLLD--AKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDY 1311 + ++ D YTC + S+T ++ V + P +I + I G + L Sbjct: 495 RLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTD-PTRITQGPADMEIIVGESIVLPCQV 553 Query: 1312 QAFP--QPNDEWIVNSKIIKKCKHTKPSIDSKSAS-LTIKKVENTDAGIYKLRLENNCGH 1368 + P + W N ++I K + ++A L I+ ++ AG Y ++ + Sbjct: 554 ASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVES 613 Query: 1369 ADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWI 1428 + + PSPP + E+ S+ + W + G S I+ Y V+ + T W Sbjct: 614 LSAVAILIVKGPPSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNYFVQTRTPFTVGWQ 672 Query: 1429 SVKNITK-----TQT-SIQNLKTNSSYRFRAYAVNEVDISDAS 1465 V + + T T ++ +L Y FR A N V + + S Sbjct: 673 RVNTVPEIIDGNTLTATVVDLNAWVEYEFRVLARNSVGVGEPS 715 Score = 86.2 bits (204), Expect = 9e-15 Identities = 93/336 (27%), Positives = 142/336 (42%), Gaps = 32/336 (9%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 GS + LEC + P P+I W K VP + + M +VL+I + ++ G Sbjct: 272 GSTVTLECFALGNPVPEITW--KRANGVPFPS-----KVKMKYSNAVLEIPSFQQDDTGG 324 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 Y VA NR G+ L PQ I+ +K + E + + G P+P+ Sbjct: 325 YECVAENRMGKNMATGRLAFYA----KPQWIQAVKDTALAIEERLHWECRANGKPKPSYA 380 Query: 768 WCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE 827 W KN + + + + D + + + D G+Y AEN G+ A + V Sbjct: 381 WLKNGQQLLSGDRITVED--GVLSVPALALSDAGMYQCVAENKHGVIYFVAELMV----- 433 Query: 828 ENAEPPLFINRFQEITVKEKG--TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 A PP F +K K T+ L + PV SI W + N I ++ IT + DG Sbjct: 434 -LASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSDG 492 Query: 886 ENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKT 945 L + NV S+ D+G Y C A N G SS R+ V T + E G++ Sbjct: 493 ---TLRLANV-SKSDAGGYTCFARNRFGMSSTTGRLL--VTDPTRITQGPADMEIIVGES 546 Query: 946 VILECQTSH----TVSTKWYHNKKEIS-GMDHREII 976 ++L CQ + VS W N + I+ G H E++ Sbjct: 547 IVLPCQVASDPVLDVSFSWAFNGQLIAKGDGHFELV 582 Score = 72.5 bits (170), Expect = 1e-10 Identities = 120/531 (22%), Positives = 214/531 (40%), Gaps = 50/531 (9%) Query: 695 LKITNVKKFQE-GTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVI 753 L I+++ ++Q+ G Y +A N G A L ++ + +V ++ VR+G+ V+ Sbjct: 114 LIISSLDRYQDVGMYQCMAFNTAG-AILSRRASLQFAYLDHFKV-HTRSAVSVREGQGVV 171 Query: 754 LSAQVVGNPRPT----ITWCKNNKPVKALPTKSDGDTHSITILKPKKVK--DEGVYTLKA 807 L + G P + W N P + L KV+ D G YT Sbjct: 172 L---LCGTPTSSGDLAYAWVFNEYPYFVQQDNRRFVSQQTGNLYIAKVEPSDVGNYTCVV 228 Query: 808 ENS--EGIAETS--AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 NS +G ++S A+I + EP + +N ++ T+ L NPVP Sbjct: 229 TNSVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVSAARGSTVTLECFALGNPVPE 288 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ITW R N + PS+ + + +E+ D D+G Y+CVA N GK+ R+ Sbjct: 289 ITWKRANGVPFPSK-VKMKYSNAVLEIPSFQQD---DTGGYECVAENRMGKNMATGRLAF 344 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGMDHREIIQEGRX 981 K +++ ++ + E + + EC+ + S W N +++ D R +++G Sbjct: 345 -YAKPQWIQAVKDTALAIE-ERLHWECRANGKPKPSYAWLKNGQQLLSGD-RITVEDG-- 399 Query: 982 XXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037 D G+ +C+ +++ L+V + P+F L +K K + Sbjct: 400 -VLSVPALALSDAGMYQCVAENKHGVIYFVAELMVLASPPDFTGNLLRALLKAKAGTTVT 458 Query: 1038 VEINSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 +E + A ++W++ G + ++ G +R + N S D G Y+C R+ Sbjct: 459 LECKPQAYPVASILWKK-GNLPIHINDRITLSSDGTLR---LANVSKSDAGGYTCFARNR 514 Query: 1095 ---SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKG---DALVRWFKDGSEI-Q 1147 S T +V P I + ++ G ++ D W +G I + Sbjct: 515 FGMSSTTGRLLVTDPTRITQGPADMEIIVGESIVLPCQVASDPVLDVSFSWAFNGQLIAK 574 Query: 1148 FSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194 H +L L I + L AG+Y C +V + AIL V+ P Sbjct: 575 GDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVESLSAVAILIVKGP 625 Score = 64.1 bits (149), Expect = 4e-08 Identities = 69/261 (26%), Positives = 111/261 (42%), Gaps = 29/261 (11%) Query: 654 ECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAV 713 ECR P+P AWL G++++ + I+V D VL + + G Y VA Sbjct: 368 ECRANGKPKPSYAWLKNGQQLLSGDRITV---ED-----GVLSVPALALSDAGMYQCVAE 419 Query: 714 NREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNN 772 N+ G + V ++ P L++++ + G +V L + P +I W K N Sbjct: 420 NKHG--VIYFVAELMVLASPPDFTGNLLRALLKAKAGTTVTLECKPQAYPVASILWKKGN 477 Query: 773 KPV---KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEEN 829 P+ + SDG + K D G YT A N G++ T+ + V +PT Sbjct: 478 LPIHINDRITLSSDGTLRLANVSK----SDAGGYTCFARNRFGMSSTTGRLLVTDPTRIT 533 Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPV--PSITWYRNNEIISPSETITQNFDGEN 887 P EI V E +I L +V +PV S +W N ++I+ + + G Sbjct: 534 QGP-----ADMEIIVGE--SIVLPCQVASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRT 586 Query: 888 I-ELVITNVDSEIDSGDYKCV 907 +L+I N+ +G Y CV Sbjct: 587 AGDLMIRNIQL-YHAGKYICV 606 Score = 60.5 bits (140), Expect = 5e-07 Identities = 112/534 (20%), Positives = 193/534 (36%), Gaps = 47/534 (8%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAKSTTKLKVE-------------VVEFPPKI-VDYEREYR 1298 L I K D YTCV+ + S TK KV+ + E+ PKI V++ Sbjct: 211 LYIAKVEPSDVGNYTCVVTN--SVTKGKVQSSPTALILRTDGMMGEYEPKIEVNFPDNVS 268 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 RGS VTL P P W + + +K + +A L I + D G Y Sbjct: 269 AARGSTVTLECFALGNPVPEITWKRANGVPFP---SKVKMKYSNAVLEIPSFQQDDTGGY 325 Query: 1359 KLRLENNCGHADVEMNVTILDKPS--PPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 + EN G + KP K L I+ + W+ N ++ Sbjct: 326 ECVAENRMGKNMATGRLAFYAKPQWIQAVKDTALAIEE---RLHWECRANGKPKPSYAWL 382 Query: 1417 VEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKE 1476 Q++ + + I+V++ S+ L + + ++ A N+ + E + Sbjct: 383 KNGQQLLSGDRITVEDGV---LSVPALALSDAGMYQCVAENKHGV--IYFVAELMVLASP 437 Query: 1477 TKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLK-TAKATYENRXXX 1535 + LK + + L C P + W + + + T + Sbjct: 438 PDFTGNLLRALLK---AKAGTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSDGTL 494 Query: 1536 XXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAV 1595 Y C A N G T+ + + IT D++ VG+ ++ Sbjct: 495 RLANVSKSDAGGYTCFARNRFGMSSTTGRLLVTDPTRITQGPADMEII--VGESIVLPCQ 552 Query: 1596 IEGIPPPEVI--WYKNGNKL-ENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + P +V W NG + + D + + + I+ ++ H+ KY Sbjct: 553 VASDPVLDVSFSWAFNGQLIAKGDGHFELVGGRTAGDLMIRNIQLYHAGKYICVVDTDVE 612 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 + S L V PS P+ V + E++ + + W D+G + Y ++ P Sbjct: 613 SLSAVAILIVKGPPSPPDS-VTVEEVTDSTAQLAWSRGRDNGS-PIVNYFVQTRTPFTVG 670 Query: 1713 WIKVADV----DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKT 1762 W +V V D + T + LN EY FRV+A+N VG E P+ ++T Sbjct: 671 WQRVNTVPEIIDGNTLTATVVDLNAWVEYEFRVLARNSVGVG---EPSPVSVRT 721 Score = 52.0 bits (119), Expect = 2e-04 Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 1865 PPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV----GG 1920 PPS P + V E T + L W+ NG SPI NY ++ +T W ++ TV G Sbjct: 625 PPSPPDSVTVEEVTDSTAQLAWSRGRDNG-SPIVNYFVQTRTPFTVGWQRVNTVPEIIDG 683 Query: 1921 SVHEHCIENIKEKDEIIFRISAENTVGVSLPT 1952 + + ++ E FR+ A N+VGV P+ Sbjct: 684 NTLTATVVDLNAWVEYEFRVLARNSVGVGEPS 715 Score = 47.6 bits (108), Expect = 0.004 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 4/80 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+TV EC+ + YP I W + I + + D TL + V DAG +TC Sbjct: 454 GTTVTLECKPQAYPVASILWKKGNLPIHINDRITLSSD----GTLRLANVSKSDAGGYTC 509 Query: 584 VAKNAAGFASSTTELIVEAP 603 A+N G +S+T L+V P Sbjct: 510 FARNRFGMSSTTGRLLVTDP 529 Score = 46.4 bits (105), Expect = 0.009 Identities = 29/75 (38%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GSTV EC G P P+ITW R + PS+ +M Y + A L I +D G + C Sbjct: 272 GSTVTLECFALGNPVPEITWKRANGVPFPSK-VKMKYSN---AVLEIPSFQQDDTGGYEC 327 Query: 584 VAKNAAGFASSTTEL 598 VA+N G +T L Sbjct: 328 VAENRMGKNMATGRL 342 Score = 46.4 bits (105), Expect = 0.009 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 6/91 (6%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKV----DV 2021 PSPP + + + V + +W D G+P++ Y + R W V V D Sbjct: 626 PSPPDS-VTVEEVTDSTAQLAWSRGR-DNGSPIVNYFVQTRTPFTVGWQRVNTVPEIIDG 683 Query: 2022 NTLKFNIRDLSENHTYMIRIYARNEIGLSEP 2052 NTL + DL+ Y R+ ARN +G+ EP Sbjct: 684 NTLTATVVDLNAWVEYEFRVLARNSVGVGEP 714 >UniRef50_Q4RV19 Cluster: Chromosome 15 SCAF14992, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15 SCAF14992, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1790 Score = 91.1 bits (216), Expect = 3e-16 Identities = 102/411 (24%), Positives = 163/411 (39%), Gaps = 31/411 (7%) Query: 1548 YKCIAFNDHGEVETS----CVVGIQQKPVITISNEDIKQKHKV--GDEWLVTAVIEGIPP 1601 Y+C+A N G +S V +++ ++ + H++ G +T V G P Sbjct: 23 YECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGGSVNITCVAVGSPM 82 Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 P V W L + E I +V+ + ++ S + YT A ++ G + Sbjct: 83 PYVKWMLGAEDLTPEDEMPIGR----NVLELNGVRES--ANYTCMAMSSLGVIEAVAQVL 136 Query: 1662 VYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDR 1721 V P KP G I+ E + SVTI W D G + Y I ++ K VD Sbjct: 137 VKTLP-KPPGTPIVTETTATSVTITW----DSGNPDPVSYYIIQYRAKGPE-SKYETVDS 190 Query: 1722 DVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXID 1780 T Y I L N EY RV A N +G + S + +T P+ I Sbjct: 191 ITTTRYSIGGLYPNTEYEIRVSAFNSIG--QGPPSARVEARTGEQAPASPPRNVQAHIIS 248 Query: 1781 NESVYITW-FPSEKNG--GSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQF 1837 +V + W P E NG + Y ++ + +W+ IQ L + TY Sbjct: 249 QNTVMVRWEEPEEPNGQVKGYRVYYTMDPSRPMNEWQIHNVQDSVITTIQNLVTSETYTI 308 Query: 1838 RIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPI 1897 ++ A +G P++ D + + P QP F V T S+ L W + G I Sbjct: 309 QVLAFTSVGDG-PFS--DPVHVKVMPGVPGQPGKFKVGRVTDTSIELTWEPAYTKEG--I 363 Query: 1898 TNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV 1948 NY + +K VK S K+ G + + +E +K E F ++A + G+ Sbjct: 364 VNYELLYKPVKFGSLEKLTF--GPRNSYTVEGLKPNTEYSFSLAAISNKGI 412 Score = 57.2 bits (132), Expect = 5e-06 Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 21/228 (9%) Query: 1253 LIIRKCTEDDQCEYTCVLLDAK-----STTKLKV----EVVEFPPKIVDYEREYRIKRGS 1303 L I E DQ +Y CV +++ S L V EV P+ + I G Sbjct: 10 LQIENSEETDQGKYECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGG 69 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 V + P P +W++ ++ + P + ++ ++ Y Sbjct: 70 SVNITCVAVGSPMPYVKWMLGAEDLT------PEDEMPIGRNVLELNGVRESANYTCMAM 123 Query: 1364 NNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGN-STIIYYVVEYQ-E 1421 ++ G + V + P PPG P + E ++S+ I WD +GN + YY+++Y+ + Sbjct: 124 SSLGVIEAVAQVLVKTLPKPPGTPIVTETTATSVTITWD----SGNPDPVSYYIIQYRAK 179 Query: 1422 IDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 +++ +V +IT T+ SI L N+ Y R A N + S E Sbjct: 180 GPESKYETVDSITTTRYSIGGLYPNTEYEIRVSAFNSIGQGPPSARVE 227 Score = 57.2 bits (132), Expect = 5e-06 Identities = 86/415 (20%), Positives = 152/415 (36%), Gaps = 23/415 (5%) Query: 1440 IQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDI 1499 I+N + ++ A N + +S Y + ++E + SP N P + Sbjct: 12 IENSEETDQGKYECVATNSQGVRYSSPANLYVRELREVRRVSPRFSILPSNHEIMPGGSV 71 Query: 1500 ELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 +TC+ G P P V W + L R Y C+A + G + Sbjct: 72 NITCVAVGSPMPYVKWMLGAEDLTPEDEMPIGR--NVLELNGVRESANYTCMAMSSLGVI 129 Query: 1560 ETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN-DKE 1618 E V ++ P + + VT + P V +Y + + + + Sbjct: 130 EAVAQVLVKTLPK-PPGTPIVTETTATS----VTITWDSGNPDPVSYYIIQYRAKGPESK 184 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-PSKPEGPVIM 1675 Y T+ I L + + + A N+ G S V + ++ P+ P V Sbjct: 185 YETVDSITTTRYSIGGLYPNTEYEIRVSAFNSIGQGPPSARVEARTGEQAPASPPRNVQA 244 Query: 1676 REISRESVTIEWKPPLDDGGL---ELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLN 1732 IS+ +V + W+ P + G Y ++ P N W ++ +V V T IQ L Sbjct: 245 HIISQNTVMVRWEEPEEPNGQVKGYRVYYTMDPSRP-MNEW-QIHNVQDSVIT-TIQNLV 301 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSE 1792 + Y +V+A VG + S+P+ +K VP D S+ +TW P+ Sbjct: 302 TSETYTIQVLAFTSVG--DGPFSDPVHVKVMPGVPGQPGKFKVGRVTDT-SIELTWEPAY 358 Query: 1793 KNGGSPIIDYKVEIKQ-EGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 G I++Y++ K + + ++ L NT Y F + A + G Sbjct: 359 TKEG--IVNYELLYKPVKFGSLEKLTFGPRNSYTVEGLKPNTEYSFSLAAISNKG 411 Score = 40.7 bits (91), Expect = 0.43 Identities = 69/304 (22%), Positives = 115/304 (37%), Gaps = 36/304 (11%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P FS P + G + + C V P P + W+ E++ P E +M + Sbjct: 52 VSPRFSILPSNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDEMPIG 103 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749 +VL++ V+ + YT +A++ G + +KT K P P V E + + Sbjct: 104 RNVLELNGVR--ESANYTCMAMSSLGVIEAVAQVLVKTLPKPPGTPIVTETTATSVTITW 161 Query: 750 ESVILSAQVVGNPRPT---ITWCKNNKPVKALPTKSDGDT--HSITILKPKKVKDEGVYT 804 +S GNP P I + P T T +SI L P E Sbjct: 162 DS--------GNPDPVSYYIIQYRAKGPESKYETVDSITTTRYSIGGLYP---NTEYEIR 210 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 + A NS G SA + + A PP R + + + T+ + P + Sbjct: 211 VSAFNSIGQGPPSARVEARTGEQAPASPP----RNVQAHIISQNTVMVRWEEPEEPNGQV 266 Query: 865 TWYRNNEIISPSETITQNFDGENI-ELVITNVDSEIDSGDY--KCVASNSAGKSSHGARV 921 YR + PS + + + N+ + VIT + + + S Y + +A S G V Sbjct: 267 KGYRVYYTMDPSRPMNE-WQIHNVQDSVITTIQNLVTSETYTIQVLAFTSVGDGPFSDPV 325 Query: 922 TIDV 925 + V Sbjct: 326 HVKV 329 >UniRef50_Q810U4 Cluster: Neuronal cell adhesion molecule precursor; n=48; Euteleostomi|Rep: Neuronal cell adhesion molecule precursor - Mus musculus (Mouse) Length = 1256 Score = 91.1 bits (216), Expect = 3e-16 Identities = 86/330 (26%), Positives = 145/330 (43%), Gaps = 33/330 (10%) Query: 633 PPTF-SKKPKAQYVDE--GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 PPTF + + + +E G+ + LEC +P P I W+ K + ++P A + Sbjct: 261 PPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWI-KEDGMLP------ANRTFYR 313 Query: 690 MYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQG 749 + L+IT+V + G Y +A N G I + +K P ++ P +++++ G Sbjct: 314 NFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAA---PYWIVAP-QNLVLSPG 369 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVK-AL--PT-KSDGDTHSITILKPKKVKDEGVYTL 805 E+ L + GNP+P I+W N P++ AL P+ K DGDT I + VY Sbjct: 370 ENGTLICRANGNPKPRISWLTNGVPIEIALDDPSRKIDGDT---IIFSNVQESSSAVYQC 426 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEI-TVKEKGTIKLVARVTRNPVPSI 864 A N G +A + V AEPP + + V L +P+P+I Sbjct: 427 NASNKYGYLLANAFVNV------LAEPPRILTSANTLYQVIANRPALLDCAFFGSPMPTI 480 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W++ + + E I D +E+ + DS +G Y CVA N G + + V ++ Sbjct: 481 EWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDS---TGTYTCVARNKLGMAKN--EVHLE 535 Query: 925 VEKVTFVKHLQKSYETEEGKTVILECQTSH 954 ++ T + + + G V EC+ H Sbjct: 536 IKDPTRIIKQPEYAVVQRGSKVSFECRVKH 565 Score = 91.1 bits (216), Expect = 3e-16 Identities = 130/588 (22%), Positives = 222/588 (37%), Gaps = 56/588 (9%) Query: 1496 NEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXXXXXXXXXXXYKCIAF 1553 N L C F G P P + W++ K + Y + Y C+A Sbjct: 463 NRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVAR 522 Query: 1554 NDHGEVETSCVVGIQQKPVITISNED--IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN 1611 N G + + I+ I E +++ KV E V IP ++W K+ Sbjct: 523 NKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPT--IMWLKDNG 580 Query: 1612 KLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV--------- 1662 +L ND+ ++ T K+ + + ++K YT A+ T ++S L+V Sbjct: 581 ELPNDERFS-TDKDH---LVVSDVKDDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAP 636 Query: 1663 -YDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEP--DNNRWIKVADV 1719 YD P+ P + ++ + SV + W P DD +TK+ IE + D W A+V Sbjct: 637 IYDVPNPPFDLELTNQLDK-SVQLTWTPG-DDNNSPITKFIIEYEDAMHDAGLWRHQAEV 694 Query: 1720 DRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTALDVPSXXXXXXXXXX 1778 +T KL+ Y FRV+A+N +G S E SE + K A P Sbjct: 695 S-GTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEASEQYLTKAA--EPDQNPMAVEGLG 751 Query: 1779 IDNESVYITWFP-SEKNGGSPIIDYKVEIKQE--GKKWKXXXXXXXXXARIQKLSINTTY 1835 + +++ ITW P + P + YKV +Q+ +W + Y Sbjct: 752 TEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPY 811 Query: 1836 QFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW--TEPESNG 1893 ++ A N++G + P + G+ L P P N VS S + W P+S Sbjct: 812 LIKVQALNDVGFA-PEPAAVMGHSGEDL-PMVAPGNVRVSVVNSTLAEVHWDPVPPKSVR 869 Query: 1894 GSPITNYIIEFKTVKGKSWT------KIVTVGGSVHEHCIENIKEKDEIIFRISAENTVG 1947 G I +KT KI+T G+ + ++ + N G Sbjct: 870 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKG 929 Query: 1948 VSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI--VMTSWGTPEWDGGAPLLGYNIAI 2005 + + T P+AP +++V + + W P G L Y + Sbjct: 930 EGPASTDRGFH-----TPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYILQY 983 Query: 2006 RDVTKTMWMEVG-----KVDVNTLKFNIRDLSENHTYMIRIYARNEIG 2048 + + T E+G K+ N ++ +++L+ + Y YA+ +G Sbjct: 984 QPINST--HELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVG 1029 Score = 89.4 bits (212), Expect = 9e-16 Identities = 140/646 (21%), Positives = 256/646 (39%), Gaps = 72/646 (11%) Query: 633 PPTFSKK-PKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT +++ PK +D +I+++C P P +W G D++ V ++ Sbjct: 39 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGSGTL 98 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQGE 750 + + EG Y A N G A S IV++ + P E L+ ++++ G+ Sbjct: 99 VINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVR---PSRSPLWTKERLEPIVLQNGQ 155 Query: 751 SVILSAQ-VVGNPRPTITWCKNNKPVKALPTKS------DGDTHSITILKPKKVKDEGVY 803 S++L + +G P I W N+ + LP +GD + +L P+ +++ + Sbjct: 156 SLVLPCRPPIGLPPAIIFWMDNS--FQRLPQSERVSQGLNGDLYFSNVL-PEDTREDYIC 212 Query: 804 TLKAENSEGIAE----TSAVITVEE----------PTE------ENAEPPLFINRFQEIT 843 + +++ I + + VI+V+E TE PP F+ + Sbjct: 213 YARFNHTQTIQQKQPISLKVISVDELNDTIAANLSDTEFYGAKSSKERPPTFLTPEGNES 272 Query: 844 VKE--KGTIKLVARVTRN-PVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEID 900 KE +G + + + P P I W + + ++ + T +NF L IT+V SE D Sbjct: 273 HKEELRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNF---KKTLQITHV-SEAD 328 Query: 901 SGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKW 960 SG+Y+C+A N+ G H VT+ V E T+I + W Sbjct: 329 SGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGTLICRANGNPKPRISW 388 Query: 961 YHNKKEIS-GMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKET 1015 N I +D +G V +C ++ + + V Sbjct: 389 LTNGVPIEIALDDPSRKIDGDTIIFSNVQESSS--AVYQCNASNKYGYLLANAFVNVLAE 446 Query: 1016 IPEFIRKLQD-FEVKEKDVAILEVE-INSETADVVWERDGEIIKPKKNKYDFEKRGHIRK 1073 P + ++V A+L+ S + W + + ++ Y G Sbjct: 447 PPRILTSANTLYQVIANRPALLDCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDNG---T 503 Query: 1074 LYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIEL 1130 L I G Y+C+ R++ A+ V ++ P II + + V +G+K +FE + Sbjct: 504 LEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRV 563 Query: 1131 TKGDAL---VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNS 1183 L + W KD E+ N + + D K L + D DD G Y+C + ++ Sbjct: 564 KHDHTLIPTIMWLKDNGEL--PNDERFSTD--KDHLVVSDVKDDDGGTYTCTANTTLDSA 619 Query: 1184 KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTW 1229 +A+L V P+ P + + D LT ++ D+++ +TW Sbjct: 620 SASAVLRVVAPT---PTPAPIYDVPNPPFDLELTNQL-DKSVQLTW 661 Score = 82.2 bits (194), Expect = 1e-13 Identities = 173/815 (21%), Positives = 302/815 (37%), Gaps = 84/815 (10%) Query: 1013 KETIPEFIRKLQDFEVKEKDVA-ILEVEINSE---TADVVWERDGEIIKPKKNKYDFEKR 1068 KE P F+ + KE+ +L +E +E T + W ++ ++ + Y R Sbjct: 258 KERPPTFLTPEGNESHKEELRGNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFY----R 313 Query: 1069 GHIRKLYIRNTSVHDEGEYSCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKAT 1125 + L I + S D G Y CI ++ T+ V+ P I QN ++ G T Sbjct: 314 NFKKTLQITHVSEADSGNYQCIAKNALGAVHHTISVTVKAAPYWIVAPQNLVLSPGENGT 373 Query: 1126 FEIELTKGDALVR--WFKDGSEIQFS-NHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 I G+ R W +G I+ + + IDG + + + Y C N Sbjct: 374 L-ICRANGNPKPRISWLTNGVPIEIALDDPSRKIDG--DTIIFSNVQESSSAVYQCNASN 430 Query: 1183 SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLDVTWY-KKKSVIE---D 1238 K +L +N L P IL ANT Y + LD ++ IE Sbjct: 431 -KYGYLLA--NAFVN-VLAEPPRILTSANT-LYQVIANRPALLDCAFFGSPMPTIEWFKG 485 Query: 1239 TEKFTLISDV----KKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-VEFPPKIVDY 1293 T+ L D+ TL I +D YTCV + K +V + ++ P +I+ Sbjct: 486 TKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTRIIKQ 545 Query: 1294 EREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVE 1351 ++RGS V+ V + P W+ ++ + + D L + V+ Sbjct: 546 PEYAVVQRGSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFSTDKDH----LVVSDVK 601 Query: 1352 NTDAGIYKLRLENNCGHADVEMNVTIL----------DKPSPPGKPNILEIDSSSINICW 1401 + D G Y A + ++ D P+PP + S+ + W Sbjct: 602 DDDGGTYTCTANTTLDSASASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTW 661 Query: 1402 DEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQ-NLKTNSSYRFRAYAVNE 1458 P + NS I +++EY++ D W ++ TQT+ Q L +Y FR A N Sbjct: 662 T-PGDDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENS 720 Query: 1459 VDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVP------QPK 1512 + S SE +E Y Q+P ++ + TEP+ + G Q K Sbjct: 721 IGRSMPSEASEQYLTKAAEPDQNPMA---VEGLGTEPDNLVITWKPLNGFQSNGPGLQYK 777 Query: 1513 VTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHG-EVETSCVVGIQQKP 1571 V+W + + N K A ND G E + V+G + Sbjct: 778 VSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDVGFAPEPAAVMGHSGED 837 Query: 1572 VITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-- 1629 + ++ +++ V + L + +PP V + G ++ K + + + + + Sbjct: 838 LPMVAPGNVRV--SVVNSTLAEVHWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEK 895 Query: 1630 -IRIKELKRSHS--------SKY--TIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREI 1678 I + ++H S Y + N G + P P ++ + Sbjct: 896 KILTFQGTKTHGMLPGLQPYSHYALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIV 955 Query: 1679 --SRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET----YCIQKLN 1732 + +S+T+EW PP G+ LT+Y ++ ++P N+ VD + + ++ LN Sbjct: 956 NPTLDSLTLEWDPPSHPNGI-LTEYILQ-YQPINSTHELGPLVDLKIPANKTRWTLKNLN 1013 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVP 1767 + Y F AQ VG + E I +P Sbjct: 1014 FSTRYKFYFYAQTSVGPGSQITEEAITTVDEAGIP 1048 Score = 63.3 bits (147), Expect = 7e-08 Identities = 51/191 (26%), Positives = 85/191 (44%), Gaps = 8/191 (4%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKS--WTKIVTVGGSVH 1923 P+ P + ++ +SV L WT P + SPIT +IIE++ + W V G+ Sbjct: 641 PNPPFDLELTNQLDKSVQLTWT-PGDDNNSPITKFIIEYEDAMHDAGLWRHQAEVSGTQT 699 Query: 1924 EHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIV 1983 ++ + FR+ AEN++G S+P+E+ L K A P A + N+V Sbjct: 700 TAQLK-LSPYVNYSFRVMAENSIGRSMPSEASEQYLTKAAEPDQNPMAVEGLGTEPDNLV 758 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVT-KTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIY 2042 +T + P L Y ++ R W V V N K+ + Y+I++ Sbjct: 759 ITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSV--VVANVSKYIVSGTPTFVPYLIKVQ 816 Query: 2043 ARNEIGLS-EP 2052 A N++G + EP Sbjct: 817 ALNDVGFAPEP 827 Score = 58.8 bits (136), Expect = 2e-06 Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 10/284 (3%) Query: 1389 ILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSS 1448 I +D+S + E + G + +Y+ E ++I TQT IQ + S Sbjct: 172 IFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQT-IQQKQPISL 230 Query: 1449 YRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN---EDIELTCIF 1505 +N+ ++ S+T E+Y K +K + PT P N + + + L CI Sbjct: 231 KVISVDELNDTIAANLSDT-EFYGA-KSSKERPPTFLTPEGNESHKEELRGNVLSLECIA 288 Query: 1506 GGVPQPKVTWYRDGKKLKTAKATYEN-RXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G+P P + W ++ L + Y N + Y+CIA N G V + Sbjct: 289 EGLPTPIIYWIKEDGMLPANRTFYRNFKKTLQITHVSEADSGNYQCIAKNALGAVHHTIS 348 Query: 1565 VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTK 1624 V ++ P ++ +++ G+ + G P P + W NG +E + + + K Sbjct: 349 VTVKAAPYWIVAPQNLVL--SPGENGTLICRANGNPKPRISWLTNGVPIEIALD-DPSRK 405 Query: 1625 EKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSK 1668 I ++ S S+ Y ASN G + V +P + Sbjct: 406 IDGDTIIFSNVQESSSAVYQCNASNKYGYLLANAFVNVLAEPPR 449 Score = 49.6 bits (113), Expect = 0.001 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G+ + EC EG P P I W ++ ++ ++ F + TL I V D+G + C Sbjct: 279 GNVLSLECIAEGLPTPIIYWIKEDGMLPANRTFYRNFKK----TLQITHVSEADSGNYQC 334 Query: 584 VAKNAAGFASSTTELIVEA 602 +AKNA G T + V+A Sbjct: 335 IAKNALGAVHHTISVTVKA 353 Score = 45.6 bits (103), Expect = 0.015 Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 +C G P P I WF+ T +D + +D+ TL I + GT+TCVA+N Sbjct: 469 DCAFFGSPMPTIEWFKGTKGSALHEDIYVLHDN---GTLEIPVAQKDSTGTYTCVARNKL 525 Query: 590 GFASSTTELIVEAP 603 G A + L ++ P Sbjct: 526 GMAKNEVHLEIKDP 539 Score = 42.7 bits (96), Expect = 0.11 Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE----WISVK-NITK 1435 PS P I+ S+ + WD P + N + Y+++YQ I++T + +K K Sbjct: 946 PSAPSSLKIVNPTLDSLTLEWDPPSHP-NGILTEYILQYQPINSTHELGPLVDLKIPANK 1004 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV 1484 T+ +++NL ++ Y+F YA V + T E + E I P V Sbjct: 1005 TRWTLKNLNFSTRYKFYFYAQTSVG-PGSQITEEAITTVDEAGIPPPDV 1052 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 7/82 (8%) Query: 524 GSTVQFECQVEGYPR--PQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTF 581 GS V FEC+V+ P I W + + + F D D+ LV+ +V +D GT+ Sbjct: 554 GSKVSFECRVKHDHTLIPTIMWLKDNGELPNDERFST--DKDH---LVVSDVKDDDGGTY 608 Query: 582 TCVAKNAAGFASSTTELIVEAP 603 TC A AS++ L V AP Sbjct: 609 TCTANTTLDSASASAVLRVVAP 630 >UniRef50_A7SWF5 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 588 Score = 90.6 bits (215), Expect = 4e-16 Identities = 95/460 (20%), Positives = 169/460 (36%), Gaps = 40/460 (8%) Query: 1294 EREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENT 1353 +R + D ++ P PN W+ K + + + SA L++ K++ Sbjct: 9 DRSRDVAEDKDFSITCSASGRPAPNVTWV------NKTSGSPVAHGTGSAILSLLKIQRH 62 Query: 1354 DAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTII 1413 AG+Y+ + N+ + + TI + P I I ++++ G + + Sbjct: 63 QAGVYQCQATNDVKRGAITQDFTI----NVQYPPEITPIQNTTVR--------AGETITL 110 Query: 1414 YYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 V + W + T ++ N + Y V+I + T+ Sbjct: 111 TCAVAGNPTPSVSWSKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVST 170 Query: 1474 IKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRX 1533 K + + E ++L+CI G P P VTW RDG + Y + Sbjct: 171 YVIVKYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTSVYYSD-- 228 Query: 1534 XXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVT 1593 Y C A N+ G + V + KP + S + ++ + Sbjct: 229 -----SVTRSEAGTYTCTATNEMGSDTNTVQVTVNYKPEMASSTTNTSSWNR--KVLSLQ 281 Query: 1594 AVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHS-SKYTIEASNTAG 1652 G+P P++ WYK G + I+ + +++ + S +Y ASN G Sbjct: 282 CKARGVPLPQITWYKPGGQPITAGVSPISGGQ----LQVTTTQDSGDYGQYKCRASNLLG 337 Query: 1653 TSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNR 1712 + + + + P P +I+ I S+ + W PP DGG + Y +E +P Sbjct: 338 SVGRLIYVTQWFSPGPP--IIIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEV-DPAKPP 394 Query: 1713 WIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEA 1752 VA I L +N EY +V A+N VG+ EA Sbjct: 395 REGVAG-----GPVVISGLTKNTEYTVKVTARNVVGYGEA 429 Score = 66.5 bits (155), Expect = 8e-09 Identities = 64/285 (22%), Positives = 115/285 (40%), Gaps = 37/285 (12%) Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 +++ V E D + C P P++ W+ K AI L + + Sbjct: 10 RSRDVAEDKDFSITCSASGRPAPNVTWVNKTSGSPVAHGTGSAI----------LSLLKI 59 Query: 701 KKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG 760 ++ Q G Y A N ++ I + PP+ I P+++ VR GE++ L+ V G Sbjct: 60 QRHQAGVYQCQATNDVKRGAITQDFTINV--QYPPE-ITPIQNTTVRAGETITLTCAVAG 116 Query: 761 NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDE-GVYTLKAENSEGIAETSAV 819 NP P+++W K S T + K E G Y A N ++ + Sbjct: 117 NPTPSVSWSKAG---------SGQSTGGNVFNEAGATKAETGQYVCTAVNI--VSGNTQT 165 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 TV +P + N + + G++KL P P +TW R+ ++SP Sbjct: 166 KTVSTYVIVKYKPSIIANSPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSP---- 221 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 T + +++ + ++G Y C A+N G ++ +VT++ Sbjct: 222 TSVYYSDSV--------TRSEAGTYTCTATNEMGSDTNTVQVTVN 258 Score = 46.0 bits (104), Expect = 0.011 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 12/75 (16%) Query: 526 TVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVA 585 +++ C +GYP P +TW R ++ P+ +YY D V +AGT+TC A Sbjct: 195 SLKLSCISDGYPAPMVTWSRDGVVVSPT---SVYYSD---------SVTRSEAGTYTCTA 242 Query: 586 KNAAGFASSTTELIV 600 N G ++T ++ V Sbjct: 243 TNEMGSDTNTVQVTV 257 Score = 45.6 bits (103), Expect = 0.015 Identities = 68/272 (25%), Positives = 96/272 (35%), Gaps = 39/272 (14%) Query: 645 VDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQ 704 V G I L C + P P ++W G S +V K + Sbjct: 102 VRAGETITLTCAVAGNPTPSVSWSKAG--------------SGQSTGGNVFNEAGATKAE 147 Query: 705 EGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVI--EPLKSMIVRQGESVILSAQVVGNP 762 G Y AVN + + K P +I P +++ G S+ LS G P Sbjct: 148 TGQYVCTAVNIVSGNTQTKTVSTYVIVKYKPSIIANSPYQTVNETTG-SLKLSCISDGYP 206 Query: 763 RPTITWCKNNKPVKALPTK-SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P +TW ++ V SD T S + G YT A N G + +T Sbjct: 207 APMVTWSRDGVVVSPTSVYYSDSVTRS----------EAGTYTCTATNEMGSDTNTVQVT 256 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 V N +P + + + K + L + P+P ITWY+ P Sbjct: 257 V------NYKPEMASSTTNTSSWNRK-VLSLQCKARGVPLPQITWYKPGG--QPITAGVS 307 Query: 882 NFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 G ++ V T DS D G YKC ASN G Sbjct: 308 PISGGQLQ-VTTTQDSG-DYGQYKCRASNLLG 337 Score = 44.4 bits (100), Expect = 0.035 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFR 1838 I+ S+ + W P +GGSP+IDYKVE+ + I L+ NT Y + Sbjct: 361 IEASSIKVNWAPPSSDGGSPVIDYKVEVDPAKPPREGVAGGPVV---ISGLTKNTEYTVK 417 Query: 1839 IYARNEIG 1846 + ARN +G Sbjct: 418 VTARNVVG 425 Score = 43.2 bits (97), Expect = 0.081 Identities = 36/133 (27%), Positives = 55/133 (41%), Gaps = 11/133 (8%) Query: 735 PQVIEPL-KSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILK 793 P PL +S V + + ++ G P P +TW NK P + +++LK Sbjct: 2 PAFNPPLDRSRDVAEDKDFSITCSASGRPAPNVTWV--NK-TSGSPVAHGTGSAILSLLK 58 Query: 794 PKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV 853 ++ GVY +A N + T+ N + P I Q TV+ TI L Sbjct: 59 IQR-HQAGVYQCQATNDVKRGAITQDFTI------NVQYPPEITPIQNTTVRAGETITLT 111 Query: 854 ARVTRNPVPSITW 866 V NP PS++W Sbjct: 112 CAVAGNPTPSVSW 124 Score = 40.3 bits (90), Expect = 0.57 Identities = 74/352 (21%), Positives = 129/352 (36%), Gaps = 44/352 (12%) Query: 844 VKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGD 903 V E + + P P++TW N SP T G I L + + +G Sbjct: 14 VAEDKDFSITCSASGRPAPNVTWV-NKTSGSPVAHGT----GSAI-LSLLKIQRH-QAGV 66 Query: 904 YKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH--TVSTKWY 961 Y+C A+N + + TI+V+ + +Q + G+T+ L C + T S W Sbjct: 67 YQCQATNDVKRGAITQDFTINVQYPPEITPIQNT-TVRAGETITLTCAVAGNPTPSVSW- 124 Query: 962 HNKKEISGMDHR-EIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI 1020 K SG + E V ++ + + ST ++VK P I Sbjct: 125 --SKAGSGQSTGGNVFNEAGATKAETGQYVCTAVNIVSGNTQTKTVSTYVIVKYK-PSII 181 Query: 1021 RKLQDFEVKEKDVAILEVEINSE---TADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIR 1077 ++ + L++ S+ V W RDG ++ P Y Sbjct: 182 AN-SPYQTVNETTGSLKLSCISDGYPAPMVTWSRDGVVVSPTS------------VYYSD 228 Query: 1078 NTSVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIEL-TK 1132 + + + G Y+C +E + T +VT V PE+ + N + N+ ++ + Sbjct: 229 SVTRSEAGTYTCTATNEMGSDTNTVQVT-VNYKPEMASSTTN--TSSWNRKVLSLQCKAR 285 Query: 1133 GDAL--VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN 1182 G L + W+K G + + + G+ Q D D G+Y C N Sbjct: 286 GVPLPQITWYKPGGQ-PITAGVSPISGGQLQVTTTQDS--GDYGQYKCRASN 334 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIE 1928 P +VS + S+ + W P S+GGSP+ +Y +E K + GG V I Sbjct: 353 PPIIIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEVDPAKP---PREGVAGGPV---VIS 406 Query: 1929 NIKEKDEIIFRISAENTVG 1947 + + E +++A N VG Sbjct: 407 GLTKNTEYTVKVTARNVVG 425 Score = 36.7 bits (81), Expect = 7.0 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 8/86 (9%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLK 2025 P PP + + + ++ + +W P DGG+P++ Y + + D K V V Sbjct: 351 PGPPI--IIVSNIEASSIKVNWAPPSSDGGSPVIDYKVEV-DPAKPPREGVAGGPV---- 403 Query: 2026 FNIRDLSENHTYMIRIYARNEIGLSE 2051 I L++N Y +++ ARN +G E Sbjct: 404 -VISGLTKNTEYTVKVTARNVVGYGE 428 >UniRef50_UPI00015B613E Cluster: PREDICTED: similar to frazzled protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to frazzled protein - Nasonia vitripennis Length = 1478 Score = 90.2 bits (214), Expect = 5e-16 Identities = 87/339 (25%), Positives = 144/339 (42%), Gaps = 31/339 (9%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P F ++P+ V G L C+L + +I WL + ++ DE+ + S Sbjct: 133 PGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMTILPS------G 186 Query: 694 VLKITNVKKFQEGTYTVVAVN-REGEASLPIVLKIKT-----GEKEPPQVIEPLKSMIVR 747 L+I V G+Y A + S L ++T GE P V +P + + Sbjct: 187 ALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIE 246 Query: 748 QGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKV--KDEGVYTL 805 + ++ L GNP+P + W K+ + S T + + L K V +D G Y Sbjct: 247 KS-TITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQC 305 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 +A+N + A + V+ P P FI R Q+ E ++ + P P IT Sbjct: 306 RAKNDIDTLDAVAEVVVQVP-------PRFIKRPQDKEASEHQELEFECEIYGKPPPLIT 358 Query: 866 WYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDV 925 W +N E+I S Q +G N+++ N ID+G ++C+ +N AG AR+TI Sbjct: 359 WLKNGEVIKLS-NYWQLTNGYNLKI---NGLLNIDAGIFQCMGTNPAGSVQASARLTIHQ 414 Query: 926 EKVTFVKHLQKSYETEEGKTVILECQTSHTV--STKWYH 962 K + + + GK V + + SH V ++ W H Sbjct: 415 PKKE--RKGPGRHRSANGKPVCKK-RLSHKVLSNSTWQH 450 Score = 74.9 bits (176), Expect = 2e-11 Identities = 103/433 (23%), Positives = 160/433 (36%), Gaps = 30/433 (6%) Query: 1649 NTAGTSSVEVTLKVY-DKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHE 1707 N G S+ E+ ++ + D PS P V + S+ I W+PP + +T Y I Sbjct: 701 NGPGASTSEIRVRTFGDVPSNPPN-VTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRP 759 Query: 1708 PDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQN-----PVGFSEALESEPIVIK- 1761 D + D + Y + +L +N Y RV A N P G SE E E Sbjct: 760 TDRRIHSSLITTDGNARYYVLNRLQKNISYQVRVCAFNVNGTGPTGCSEWQEVETYENDL 819 Query: 1762 TALDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI-KQEGKKWKXXXXXX 1820 + DVPS D S+ + W P KN + Y + K ++K Sbjct: 820 SESDVPSAPTNLKTNPMSD--SIDVRWGP-PKNQSIKVRGYVLTWGKGIPDEYKKVLDGK 876 Query: 1821 XXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDKIT------IGKTLTPPSQPRNFVV 1874 +I L N+ Y + A+NE G L + + T LTPP + V+ Sbjct: 877 QRYYQIDNLEPNSDYVITLRAKNEAGEGLQVYENVRTTEKTSAESAAPLTPPVGLKTVVM 936 Query: 1875 SESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKD 1934 S ST V L WT+ ++ + YI+ + + S + + I ++K Sbjct: 937 SSST---VVLHWTDSKNQHVTDNRYYIVRYTSYHRSSNQRYKYYNTTDLNCMIHDLKPNT 993 Query: 1935 EIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGS--NIVMTSWGTPEW 1992 E F + G S V + PS P L ++ + V+ W P+ Sbjct: 994 EYEFTVKV--VKGRRESPWSMVVMNKTLEAKPSSPPRDLTVQSIDEYPKSVLLRWLPPKL 1051 Query: 1993 DGGAPLLGYNIAI---RDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 G + GY I + + W V T +L + TY +I ARN G Sbjct: 1052 SNG-DINGYIIRYTTDNNKDERDWKTEAFVGDKTEFVLPAELQPSTTYYFKIGARNAKGY 1110 Query: 2050 SEPLESDEPFKVI 2062 P S P++ + Sbjct: 1111 G-PFSSTVPYRTL 1122 Score = 71.3 bits (167), Expect = 3e-10 Identities = 91/360 (25%), Positives = 146/360 (40%), Gaps = 36/360 (10%) Query: 861 VPSITWYRNNEIISPSETITQNFDG--ENIELVITNVDSEIDSGDYKCVAS-NSAGKSSH 917 +P ITW E P I + EN L I+ + E G Y+CVAS + G + Sbjct: 66 LPVITW--RTEDGQPINFIGDKYRSQLENGSLYISAANQE-SIGSYQCVASIENVGAIAS 122 Query: 918 GARVTIDVEKVTFVKHLQKSYETEEGKTVILECQ--TSHTVSTKWYHNKKEISGMDHREI 975 V F + Q + G+ L C+ TS V+ +W +++ + + R Sbjct: 123 RTAVVKLASLPGFDREPQDTM-VYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDESRMT 181 Query: 976 IQEGRXXXXXXXXXXXXDVGVIKCIVKD-----QETSTMLVVK-------ETIPEFIRKL 1023 I DVG +C T L ++ E++P F+ K Sbjct: 182 ILPS--GALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKP 239 Query: 1024 QDFEVKEKDVAILEVEINSETA-DVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVH 1082 + EK LE N +V W +DG I ++ L I++ + Sbjct: 240 FNQVAIEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVA-ASSLMIKDVTEE 298 Query: 1083 DEGEYSCILRDESCTAEVT---VVELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVR 1138 D G Y C +++ T + VV++PP I R Q+++ ++ + FE E+ K L+ Sbjct: 299 DNGSYQCRAKNDIDTLDAVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLIT 358 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSC----EVGNSKCTAILTVEEP 1194 W K+G I+ SN+ QLT LKI DAG + C G+ + +A LT+ +P Sbjct: 359 WLKNGEVIKLSNYWQLT---NGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415 Score = 70.1 bits (164), Expect = 6e-10 Identities = 80/377 (21%), Positives = 147/377 (38%), Gaps = 19/377 (5%) Query: 1678 ISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEY 1737 ++ V + W+ P G E++ Y I + R ++ R+ T I L Y Sbjct: 539 VNSRFVALRWQEPEITSG-EISNYLIYYKQEGFERE-RIERTPREETTVTISGLQPGTTY 596 Query: 1738 MFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWF-PSEKNGG 1796 +FR +A S + + + ++ +VPS ++S+ ++W P+ NG Sbjct: 597 LFRAVANVSNVLSASSKVLELTTESEPNVPSHPLNLRGWPT-SSQSIMLSWEEPTTTNGR 655 Query: 1797 SPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLPYTSDDK 1856 I Y + EG + + L Y + A N+ G P S + Sbjct: 656 --ISGYLITYA-EGDYEELNRNTTNTSYELTGLKPYREYNIWVQAINDNG---PGASTSE 709 Query: 1857 ITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIV 1916 I + PS P N + + S+ ++W P IT Y I ++ + + ++ Sbjct: 710 IRVRTFGDVPSNPPNVTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRPTDRRIHSSLI 769 Query: 1917 TVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT---ESQSVR-LEKHATVPSPPTAP 1972 T G+ + + +++ R+ A N G PT E Q V E + P+AP Sbjct: 770 TTDGNARYYVLNRLQKNISYQVRVCAFNVNGTG-PTGCSEWQEVETYENDLSESDVPSAP 828 Query: 1973 LEIRM-VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDL 2031 ++ S+ + WG P+ + + GY + + +V +D + I +L Sbjct: 829 TNLKTNPMSDSIDVRWGPPK-NQSIKVRGYVLTWGKGIPDEYKKV--LDGKQRYYQIDNL 885 Query: 2032 SENHTYMIRIYARNEIG 2048 N Y+I + A+NE G Sbjct: 886 EPNSDYVITLRAKNEAG 902 Score = 62.5 bits (145), Expect = 1e-07 Identities = 81/351 (23%), Positives = 136/351 (38%), Gaps = 27/351 (7%) Query: 1047 VVWE-RDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTA---EVTV 1102 + W DG+ I +KY + LYI + G Y C+ E+ A V Sbjct: 69 ITWRTEDGQPINFIGDKYRSQLENG--SLYISAANQESIGSYQCVASIENVGAIASRTAV 126 Query: 1103 VELP--PEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGK 1159 V+L P Q+ V G A +L D + ++W KD + ++TI Sbjct: 127 VKLASLPGFDREPQDTMVYPGQIAYLSCKLATSDQVNIQWLKDEQPLLLDES-RMTIL-P 184 Query: 1160 KQKLKIYDCDLDDAGEYSCEV---GNSKCT--AILTVEEPSINFTLRLPEFILVPANTDA 1214 L+I + D G Y C G + + A L ++ I +P F+ P N A Sbjct: 185 SGALEIDEVLPGDVGSYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVA 244 Query: 1215 Y----LTVEIP---DETLDVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYT 1267 +T+E + +V W K + I+ + V +L+I+ TE+D Y Sbjct: 245 IEKSTITLECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQ 304 Query: 1268 CVLLDAKSTTKLKVE-VVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSK 1326 C + T E VV+ PP+ + ++ ++ + P P W+ N + Sbjct: 305 CRAKNDIDTLDAVAEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGE 364 Query: 1327 IIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTI 1377 +IK + + + +L I + N DAGI++ N G +TI Sbjct: 365 VIKLSNYWQL---TNGYNLKINGLLNIDAGIFQCMGTNPAGSVQASARLTI 412 Score = 58.8 bits (136), Expect = 2e-06 Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 5/126 (3%) Query: 479 NYTQYLQKKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPR 538 N + + Q +L+ K +L + E +SM P+FV K + + ST+ EC G P+ Sbjct: 204 NASGFGQYRLSTKA-QLALQTSDIGEGESM-PVFVAKPFNQVAIEKSTITLECAANGNPK 261 Query: 539 PQITWFRQ-TAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 P++ W + T+I S D + Y ++L+I++V ED G++ C AKN + E Sbjct: 262 PEVYWLKDGTSIDLASLDSR--YQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVAE 319 Query: 598 LIVEAP 603 ++V+ P Sbjct: 320 VVVQVP 325 Score = 58.4 bits (135), Expect = 2e-06 Identities = 51/229 (22%), Positives = 85/229 (37%), Gaps = 10/229 (4%) Query: 1448 SYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG 1507 SYR A + +S ++ I E + V KP + E + I L C G Sbjct: 200 SYRCNASGFGQYRLSTKAQLALQTSDIGEGESMPVFVAKPFNQVAIEKST-ITLECAANG 258 Query: 1508 VPQPKVTWYRDGKKLKTAK--ATYENRXXXXXXXXXXXXXX--XYKCIAFNDHGEVETSC 1563 P+P+V W +DG + A + Y+ Y+C A ND ++ Sbjct: 259 NPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKDVTEEDNGSYQCRAKNDIDTLDAVA 318 Query: 1564 VVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 V +Q P +D + E I G PPP + W KNG ++ + +T Sbjct: 319 EVVVQVPPRFIKRPQDKEASEH--QELEFECEIYGKPPPLITWLKNGEVIKLSNYWQLTN 376 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGP 1672 ++I L + + +N AG+ L ++ + +GP Sbjct: 377 GYN---LKINGLLNIDAGIFQCMGTNPAGSVQASARLTIHQPKKERKGP 422 Score = 57.2 bits (132), Expect = 5e-06 Identities = 29/94 (30%), Positives = 46/94 (48%), Gaps = 4/94 (4%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P F+++ + K + ++FEC++ G P P ITW + +IK S Y+ N L Sbjct: 326 PRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVIKLSN----YWQLTNGYNLK 381 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 I + DAG F C+ N AG ++ L + P Sbjct: 382 INGLLNIDAGIFQCMGTNPAGSVQASARLTIHQP 415 Score = 54.0 bits (124), Expect = 4e-05 Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 12/192 (6%) Query: 1859 IGKTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 +G+ T P PRN + SR V L+W EPE G I+NY+I +K +G +I Sbjct: 521 LGEAGTLPLAPRNLSIGLVNSRFVALRWQEPEITSGE-ISNYLIYYKQ-EGFERERIERT 578 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIR-- 1976 I ++ +FR A V L S+ + L + P+ P+ PL +R Sbjct: 579 PREETTVTISGLQPGTTYLFRAVA--NVSNVLSASSKVLELTTESE-PNVPSHPLNLRGW 635 Query: 1977 MVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHT 2036 S +M SW P G + GY I + + E+ + NT + + L Sbjct: 636 PTSSQSIMLSWEEPTTTNGR-ISGYLITYAEGD---YEELNRNTTNT-SYELTGLKPYRE 690 Query: 2037 YMIRIYARNEIG 2048 Y I + A N+ G Sbjct: 691 YNIWVQAINDNG 702 Score = 41.1 bits (92), Expect = 0.33 Identities = 17/49 (34%), Positives = 27/49 (55%) Query: 626 ADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEI 674 A+++ +PP F K+P+ + E ++ EC + P P I WL GE I Sbjct: 318 AEVVVQVPPRFIKRPQDKEASEHQELEFECEIYGKPPPLITWLKNGEVI 366 Score = 40.3 bits (90), Expect = 0.57 Identities = 41/190 (21%), Positives = 81/190 (42%), Gaps = 19/190 (10%) Query: 1386 KP-NILEIDSSSINICWDEPENTGN-STIIYYVVEYQEIDTTEWIS-VKNITKTQTSIQN 1442 KP N + I+ S+I + E GN +Y++ + ID S + + + I++ Sbjct: 238 KPFNQVAIEKSTITL---ECAANGNPKPEVYWLKDGTSIDLASLDSRYQTVAASSLMIKD 294 Query: 1443 LKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTEPNEDIE 1500 + + ++ A N++D DA + E +Q P +++P +E ++++E Sbjct: 295 VTEEDNGSYQCRAKNDIDTLDA---------VAEVVVQVPPRFIKRPQDKEASE-HQELE 344 Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKA-TYENRXXXXXXXXXXXXXXXYKCIAFNDHGEV 1559 C G P P +TW ++G+ +K + N ++C+ N G V Sbjct: 345 FECEIYGKPPPLITWLKNGEVIKLSNYWQLTNGYNLKINGLLNIDAGIFQCMGTNPAGSV 404 Query: 1560 ETSCVVGIQQ 1569 + S + I Q Sbjct: 405 QASARLTIHQ 414 Score = 38.3 bits (85), Expect = 2.3 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 6/89 (6%) Query: 1373 MNVTILDKPSPPGKPNILE---IDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWIS 1429 + +T +P+ P P L S SI + W+EP T N I Y++ Y E D E Sbjct: 615 LELTTESEPNVPSHPLNLRGWPTSSQSIMLSWEEPTTT-NGRISGYLITYAEGDYEE--L 671 Query: 1430 VKNITKTQTSIQNLKTNSSYRFRAYAVNE 1458 +N T T + LK Y A+N+ Sbjct: 672 NRNTTNTSYELTGLKPYREYNIWVQAIND 700 Score = 37.5 bits (83), Expect = 4.0 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 11/133 (8%) Query: 1335 KPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHA-DVEMNVTILDKPS--------PPG 1385 K +D K I +E + LR +N G V NV +K S PP Sbjct: 870 KKVLDGKQRYYQIDNLEPNSDYVITLRAKNEAGEGLQVYENVRTTEKTSAESAAPLTPPV 929 Query: 1386 KPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI--DTTEWISVKNITKTQTSIQNL 1443 + + SS++ + W + +N + YY+V Y + + N T I +L Sbjct: 930 GLKTVVMSSSTVVLHWTDSKNQHVTDNRYYIVRYTSYHRSSNQRYKYYNTTDLNCMIHDL 989 Query: 1444 KTNSSYRFRAYAV 1456 K N+ Y F V Sbjct: 990 KPNTEYEFTVKVV 1002 Score = 36.7 bits (81), Expect = 7.0 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 5/140 (3%) Query: 1363 ENNCGHADVEMNV-TILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQE 1421 +N G + E+ V T D PS P I ++SI I W+ P N I Y + Y+ Sbjct: 700 DNGPGASTSEIRVRTFGDVPSNPPNVTIEAGGATSIVIRWEPPSEGQNGIITGYKIRYRP 759 Query: 1422 IDTTEWISV--KNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV-IKETK 1478 D S+ + + L+ N SY+ R A N V+ + + +E+ +V E Sbjct: 760 TDRRIHSSLITTDGNARYYVLNRLQKNISYQVRVCAFN-VNGTGPTGCSEWQEVETYEND 818 Query: 1479 IQSPTVEKPLKNITTEPNED 1498 + V N+ T P D Sbjct: 819 LSESDVPSAPTNLKTNPMSD 838 >UniRef50_UPI000065FAD3 Cluster: Homolog of Brachydanio rerio "Neural adhesion molecule L1.2.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Neural adhesion molecule L1.2. - Takifugu rubripes Length = 1204 Score = 90.2 bits (214), Expect = 5e-16 Identities = 141/689 (20%), Positives = 274/689 (39%), Gaps = 66/689 (9%) Query: 830 AEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIE 889 ++PP+ + IT I L + NP P+ W ++ +I S E E Sbjct: 3 SQPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIR-SGLHLGTLKAEEEE 61 Query: 890 LVITNVDSEIDSGDYKCVASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKTVIL 948 + + G Y+C ASN G + + +V ++ + V K Q E+ EG+++IL Sbjct: 62 PL------QQFEGHYRCYASNDYGTAMTQSVQVIVEAQPV-LPKQQQVHKESYEGESIIL 114 Query: 949 ECQTSHTVSTKWYH-----------NKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVI 997 C + + H +++ + G+D + Sbjct: 115 SCNPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLYFSNLLRNDSRTDYMCNAQYLAA 174 Query: 998 KCIVKDQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSETADVVWER--DGEI 1055 + I+ + S +V + + RK F+ ++L + + T + + + ++ Sbjct: 175 RTILTESVISLTVVPSNDVAQ-ARKPHFFKHTGPHSSVLALRGHKVTLECIPKGLPTPKV 233 Query: 1056 IKPKKNKYDFEKRG----HIRKLYIRNTSVHDEGEYSCILRDES--CTAEVTV-VELPPE 1108 KK+ E G H R + + ++D+GEY C + T TV VE P Sbjct: 234 EWKKKDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKAWNSHGFTTHSFTVTVEAAPY 293 Query: 1109 IITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEI-QFSNHIQLTIDGKKQKLKIY 1166 + + +Q + G + + + W +G I + + ++ G L+ Sbjct: 294 WVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILR-- 351 Query: 1167 DCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETLD 1226 D D Y CE N +A+L + + LP IL +D L Sbjct: 352 DVVFADTAVYQCEATNKHGSALLN----TFLHVVELPPQILT---SDGLL--------YR 396 Query: 1227 VTWYKKKSVIEDTEKF-TLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVE 1285 VT + ++++ D E F + + TL+I + DD Y+C + + + + Sbjct: 397 VT--EGRNILMDCEVFGSPRPHITCGTLVISEVDHDDAGVYSCSVKH-NNNVSINAHLEV 453 Query: 1286 FPPKIVDYE-REYRIKRGSDVTLLVDYQAFPQPNDEWIV----NSKIIKKCKHTKPSIDS 1340 + ++ + R RG++ L + P+ +V K++ K S+ Sbjct: 454 YNRTVIPAPPQNLRFLRGTNALLTCGFYTDPRLPPAQVVWRRDGHKLMGSETANKYSV-F 512 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 + +L + ++ D+ Y + + H ++T++D+P PP ++ E+ ++ + Sbjct: 513 EDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMGSITVVDRPDPPKYLSLAEVTDHNLTLN 572 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTE-----WISVKNITKTQTSIQ-NLKTNSSYRFRAY 1454 W P + NS +I ++VE++E TE W +K + +Q +L+ +YRFR Sbjct: 573 WT-PGSAHNSPMIDFIVEFREEQHTEGKKWKWEEMKKVPADVQHVQLSLRPFCTYRFRVI 631 Query: 1455 AVNEVDISDASETTEYYKVIKETKIQSPT 1483 AVNEV SD SE ++ Y+ ++PT Sbjct: 632 AVNEVGRSDPSEPSDTYRTSPAVPDRNPT 660 Score = 79.8 bits (188), Expect = 8e-13 Identities = 68/299 (22%), Positives = 134/299 (44%), Gaps = 21/299 (7%) Query: 1599 IPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEV 1658 +PP +V+W ++G+KL + N + + +++ ++ + S++Y+ E + Sbjct: 486 LPPAQVVWRRDGHKLMGSETANKYSVFEDGTLKVSNIQFNDSAQYSCEVISLLDHVKAMG 545 Query: 1659 TLKVYDKPSKPEGPVIMREISRESVTIEWKP------PLDDGGLELTKYAIEKH-EPDNN 1711 ++ V D+P P+ + + E++ ++T+ W P P+ D + ++ E+H E Sbjct: 546 SITVVDRPDPPK-YLSLAEVTDHNLTLNWTPGSAHNSPMID---FIVEFREEQHTEGKKW 601 Query: 1712 RWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXX 1771 +W ++ V DV+ + L C Y FRVIA N VG S+ E +T+ VP Sbjct: 602 KWEEMKKVPADVQ-HVQLSLRPFCTYRFRVIAVNEVGRSDPSEPSD-TYRTSPAVPDRNP 659 Query: 1772 XXXXXXXIDNESVYITWFPSEK---NGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQ 1827 D +S+ ITW +K NG + + E ++ +W +Q Sbjct: 660 TGVRSESADPDSLVITWDEMDKMYHNGHGFLYEVSWREARKRDARWNSAEVKSPPFL-VQ 718 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 T ++ ++ A N +G+ P + G+ P++P V + + +VT+KW Sbjct: 719 NTGTYTPFEIKVKAVNSLGSG-PAPEPEIGHSGE--DKPAEPPTGVKTTVINSTVTVKW 774 Score = 65.7 bits (153), Expect = 1e-08 Identities = 107/491 (21%), Positives = 181/491 (36%), Gaps = 58/491 (11%) Query: 640 PKAQYVD----EGSDILLECRLVAIPEPDIA-WLFK-GEEIVPDENISVAIESDMHMYCS 693 PK Q V EG I+L C P + W+ K I E + V ++ ++ + + Sbjct: 97 PKQQQVHKESYEGESIILSCNPPESSTPPVIHWMDKLMVHISQSERVLVGLDGKLY-FSN 155 Query: 694 VLKITNVKKFQEGTYTVVA--VNREGEASLPIVLKIKTGEKEPPQVIE---PLKSMIVRQ 748 +L+ + + + A + E SL +V + P + P S++ + Sbjct: 156 LLRNDSRTDYMCNAQYLAARTILTESVISLTVVPSNDVAQARKPHFFKHTGPHSSVLALR 215 Query: 749 GESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI-LKPKKVKDEGVYTLKA 807 G V L G P P + W K K + T D H+ + + D+G Y KA Sbjct: 216 GHKVTLECIPKGLPTPKVEWKK--KDGRLGETSGQLDKHNRWFHFESIGLNDDGEYECKA 273 Query: 808 ENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWY 867 NS G S +TVE P ++ + T++L + P PSITW Sbjct: 274 WNSHGFTTHSFTVTVEAA-------PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWS 326 Query: 868 RNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEK 927 N I+ E + + L++ +V D+ Y+C A+N G + + + Sbjct: 327 INGRNITEVEEEPRRSVSGGV-LILRDV-VFADTAVYQCEATNKHGSALLNTFLHVVELP 384 Query: 928 VTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEGRXXXXXXX 987 + Y EG+ ++++C+ + IS +DH Sbjct: 385 PQILTSDGLLYRVTEGRNILMDCEVFGSPRPHITCGTLVISEVDH--------------- 429 Query: 988 XXXXXDVGVIKCIVKDQETSTMLVVKETIPEFI--RKLQDFEVKEKDVAILEVEINSE-- 1043 D GV C VK ++ E + Q+ A+L ++ Sbjct: 430 ----DDAGVYSCSVKHNNNVSINAHLEVYNRTVIPAPPQNLRFLRGTNALLTCGFYTDPR 485 Query: 1044 --TADVVWERDGEIIKPKK--NKYDFEKRGHIRKLYIRNTSVHDEGEYSC----ILRDES 1095 A VVW RDG + + NKY + G ++ + N +D +YSC +L Sbjct: 486 LPPAQVVWRRDGHKLMGSETANKYSVFEDGTLK---VSNIQFNDSAQYSCEVISLLDHVK 542 Query: 1096 CTAEVTVVELP 1106 +TVV+ P Sbjct: 543 AMGSITVVDRP 553 Score = 60.9 bits (141), Expect = 4e-07 Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 4/181 (2%) Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTW-YRDGKKLKTAKATYENRXXXXXXXXXXXXX 1545 P ++ + L CI G+P PKV W +DG+ +T+ ++ Sbjct: 207 PHSSVLALRGHKVTLECIPKGLPTPKVEWKKKDGRLGETSGQLDKHNRWFHFESIGLNDD 266 Query: 1546 XXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVI 1605 Y+C A+N HG S V ++ P + Q + G+ + EGIP P + Sbjct: 267 GEYECKAWNSHGFTTHSFTVTVEAAPYWV--KKPASQLYSPGETVRLDCQAEGIPTPSIT 324 Query: 1606 WYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK 1665 W NG + + E V+ ++++ + ++ Y EA+N G++ + L V + Sbjct: 325 WSINGRNI-TEVEEEPRRSVSGGVLILRDVVFADTAVYQCEATNKHGSALLNTFLHVVEL 383 Query: 1666 P 1666 P Sbjct: 384 P 384 Score = 58.8 bits (136), Expect = 2e-06 Identities = 107/542 (19%), Positives = 207/542 (38%), Gaps = 65/542 (11%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXX---XXXXXX 1540 V+KP + + P E + L C G+P P +TW +G+ + + Sbjct: 295 VKKPASQLYS-PGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGVLILRDV 353 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y+C A N HG + + + + P ++++ + + G L+ + G P Sbjct: 354 VFADTAVYQCEATNKHGSALLNTFLHVVELPPQILTSDGLLYRVTEGRNILMDCEVFGSP 413 Query: 1601 PPEVIWYKNG-NKLENDKE--YNITTKEKTSVIRIKELKRSHSSKYTIEASN---TAGTS 1654 P + +++++D Y+ + K +V L+ + + N GT+ Sbjct: 414 RPHITCGTLVISEVDHDDAGVYSCSVKHNNNVSINAHLEVYNRTVIPAPPQNLRFLRGTN 473 Query: 1655 SVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 ++ +T Y P P V+ R DG + K+ + + Sbjct: 474 AL-LTCGFYTDPRLPPAQVVWRR---------------DGHKLMGSETANKYSVFEDGTL 517 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXX 1774 KV+++ + N++ +Y VI+ + +A+ S +V + D P Sbjct: 518 KVSNI----------QFNDSAQYSCEVISL--LDHVKAMGSITVVDRP--DPPK----YL 559 Query: 1775 XXXXIDNESVYITWFPSEKNGGSPIIDYKVEIKQ----EGKKWKXXXXXXXXXARIQKLS 1830 + + ++ + W P + SP+ID+ VE ++ EGKKWK A +Q + Sbjct: 560 SLAEVTDHNLTLNWTPGSAH-NSPMIDFIVEFREEQHTEGKKWK-WEEMKKVPADVQHVQ 617 Query: 1831 IN----TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKW 1886 ++ TY+FR+ A NE+G S P D + P P + S+ + W Sbjct: 618 LSLRPFCTYRFRVIAVNEVGRSDPSEPSDTYRTSPAV-PDRNPTGVRSESADPDSLVITW 676 Query: 1887 TEPES---NGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAE 1943 E + NG + Y + ++ + K + + ++N ++ A Sbjct: 677 DEMDKMYHNGHGFL--YEVSWREAR-KRDARWNSAEVKSPPFLVQNTGTYTPFEIKVKAV 733 Query: 1944 NTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI 2003 N++G S P + PPT ++ ++ S + + W + D LLGY I Sbjct: 734 NSLG-SGPAPEPEIGHSGEDKPAEPPTG-VKTTVINSTVTV-KWDAAQ-DVRGLLLGYKI 789 Query: 2004 AI 2005 I Sbjct: 790 HI 791 Score = 58.0 bits (134), Expect = 3e-06 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Query: 634 PTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCS 693 P + KKP +Q G + L+C+ IP P I W G I E E + Sbjct: 292 PYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEE-----EPRRSVSGG 346 Query: 694 VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI-VRQGESV 752 VL + +V Y A N+ G A L L + + PPQ++ + V +G ++ Sbjct: 347 VLILRDVVFADTAVYQCEATNKHGSALLNTFLHV---VELPPQILTSDGLLYRVTEGRNI 403 Query: 753 ILSAQVVGNPRPTIT 767 ++ +V G+PRP IT Sbjct: 404 LMDCEVFGSPRPHIT 418 Score = 47.6 bits (108), Expect = 0.004 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATL 568 AP +V+K + G TV+ +CQ EG P P ITW I ++ V L Sbjct: 291 APYWVKKPASQLYSPGETVRLDCQAEGIPTPSITWSINGRNITEVEEEPRRSVSGGV--L 348 Query: 569 VIREVFPEDAGTFTCVAKNAAGFASSTTEL-IVEAP 603 ++R+V D + C A N G A T L +VE P Sbjct: 349 ILRDVVFADTAVYQCEATNKHGSALLNTFLHVVELP 384 Score = 41.5 bits (93), Expect = 0.25 Identities = 31/128 (24%), Positives = 51/128 (39%), Gaps = 3/128 (2%) Query: 1480 QSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXX 1539 Q P + + ++IT DI L C G P P W +DG +++ + Sbjct: 4 QPPVLSEVPESITAFSPVDIHLPCKAKGNPPPTFHWMKDGVLIRS--GLHLGTLKAEEEE 61 Query: 1540 XXXXXXXXYKCIAFNDHGEVETSCV-VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEG 1598 Y+C A ND+G T V V ++ +PV+ + K+ ++ L E Sbjct: 62 PLQQFEGHYRCYASNDYGTAMTQSVQVIVEAQPVLPKQQQVHKESYEGESIILSCNPPES 121 Query: 1599 IPPPEVIW 1606 PP + W Sbjct: 122 STPPVIHW 129 Score = 40.3 bits (90), Expect = 0.57 Identities = 31/126 (24%), Positives = 50/126 (39%), Gaps = 6/126 (4%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCI 1728 P + ++ S SV + W PP + G+ L K E N+ + D V + + Sbjct: 875 PPASLRLQSPSETSVILYWAPPTEANGILLGYVIQHKQEGANSESLLQMISDPSVTHFEL 934 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 L+ N Y+F+VIA G E PI ++ A + S ++W Sbjct: 935 HHLDPNSYYIFKVIAYTAAG-----EGPPIQLRGATMLEGVPPSNVTIVT-GTTSFNLSW 988 Query: 1789 FPSEKN 1794 P E+N Sbjct: 989 VPEERN 994 Score = 39.1 bits (87), Expect = 1.3 Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 12/105 (11%) Query: 1966 PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKT-----MWMEVGKV- 2019 P PP L + V + + +W TP +P++ + + R+ T W E+ KV Sbjct: 553 PDPPKY-LSLAEVTDHNLTLNW-TPGSAHNSPMIDFIVEFREEQHTEGKKWKWEEMKKVP 610 Query: 2020 -DVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIP 2063 DV ++ ++R TY R+ A NE+G S+P E + ++ P Sbjct: 611 ADVQHVQLSLRPFC---TYRFRVIAVNEVGRSDPSEPSDTYRTSP 652 >UniRef50_Q05D81 Cluster: MYLK protein; n=14; Eutheria|Rep: MYLK protein - Homo sapiens (Human) Length = 236 Score = 90.2 bits (214), Expect = 5e-16 Identities = 41/116 (35%), Positives = 66/116 (56%) Query: 486 KKLNEKIDKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFR 545 +KL + E E+ + P F + +R +GS +F+C++EGYP P++ WF+ Sbjct: 97 EKLESEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 156 Query: 546 QTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVE 601 I+ S+ FQ+ YD+D +L+I +V +D +TC A N+ G A+ T ELIVE Sbjct: 157 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212 Score = 49.6 bits (113), Expect = 0.001 Identities = 32/101 (31%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 + P FSK + V EGS +C++ P+P++ W FK ++ + E+ I+ D Sbjct: 119 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVW-FKDDQSI-RESRHFQIDYDEDGN 176 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEK 732 CS++ I++V + YT AVN GEA+ L ++T E+ Sbjct: 177 CSLI-ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 216 Score = 44.8 bits (101), Expect = 0.026 Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Query: 805 LKAENSEGIAETSAVITVEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 L AE E +E + +E EE P F +++ V E + ++ P P Sbjct: 94 LNAEKLE--SEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPE 151 Query: 864 ITWYRNNEIISPSETITQNFDGE-NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVT 922 + W+++++ I S ++D + N L+I++V + D Y C A NS G+++ A + Sbjct: 152 VVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-DDAKYTCKAVNSLGEATCTAELI 210 Query: 923 ID 924 ++ Sbjct: 211 VE 212 Score = 42.3 bits (95), Expect = 0.14 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 1107 PEIITRLQNQKVNKGNKATFEIELTK-GDALVRWFKDGSEIQFSNHIQLTIDGKKQ-KLK 1164 P +++ +V +G+ A F+ ++ D V WFKD I+ S H Q+ D L Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180 Query: 1165 IYDCDLDDAGEYSCE----VGNSKCTAILTVE 1192 I D DD +Y+C+ +G + CTA L VE Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212 Score = 40.7 bits (91), Expect = 0.43 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 1596 IEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSV-IRIKELKRSHSSKYTIEASNTAGTS 1654 IEG P PEV+W+K+ + + + I E + + I ++ +KYT +A N+ G + Sbjct: 144 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 203 Query: 1655 SVEVTLKV 1662 + L V Sbjct: 204 TCTAELIV 211 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/100 (25%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 735 PQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKA---LPTKSDGDTHSITI 791 P + ++ + V +G + ++ G P P + W K+++ ++ D D + I Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180 Query: 792 LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 + D+ YT KA NS G A +A + VE E E Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 220 >UniRef50_Q9Y6N7 Cluster: Roundabout homolog 1 precursor; n=74; Coelomata|Rep: Roundabout homolog 1 precursor - Homo sapiens (Human) Length = 1651 Score = 90.2 bits (214), Expect = 5e-16 Identities = 78/327 (23%), Positives = 132/327 (40%), Gaps = 25/327 (7%) Query: 605 SDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPD 664 SD G + V A++ P+F K+P V +C P P Sbjct: 233 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 292 Query: 665 IAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIV 724 + W K + +P + D H LKI V G+YT VA N G+A Sbjct: 293 VRWR-KDDGELPKSRYEI---RDDH----TLKIRKVTAGDMGSYTCVAENMVGKAEASAT 344 Query: 725 LKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN--------KPVK 776 L + +EPP + + +V G +V + GNP+P I W + +P + Sbjct: 345 LTV----QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQ 400 Query: 777 ALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFI 836 + S T +TI ++ D G Y + N G T A + V + + PP+ Sbjct: 401 SSSRFSVSQTGDLTITNVQR-SDVGYYICQTLNVAGSIITKAYLEVTDVIADR-PPPVIR 458 Query: 837 NRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVD 896 TV GT L T +PVP+I W ++ ++S ++ + + +++ + Sbjct: 459 QGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLG 518 Query: 897 SEIDSGDYKCVASNSAGKSSHGARVTI 923 D+G Y C+AS +G+++ A + + Sbjct: 519 ---DTGRYTCIASTPSGEATWSAYIEV 542 Score = 79.4 bits (187), Expect = 1e-12 Identities = 108/484 (22%), Positives = 179/484 (36%), Gaps = 44/484 (9%) Query: 630 EGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMH 689 E PP + P V +G L C+ P P I W GE + D++ + + Sbjct: 64 EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123 Query: 690 M-YCSVLKITNVKKFQ--EGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMI 745 L+I + +K + EG Y VA N GEA S L++ + Q P ++ Sbjct: 124 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQ--NP-SDVM 180 Query: 746 VRQGESVILSAQVV-GNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 V GE ++ Q G+P PTI+W K+ P+ + + I +K D G Y Sbjct: 181 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK-SDAGKYV 239 Query: 805 LKAENSEGIAETS-AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPS 863 N G E+ A +TV E P F+ R + V + + +PVP+ Sbjct: 240 CVGTNMVGERESEVAELTV-------LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPT 292 Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 + W +++ + S ++ I V D G Y CVA N GK+ A +T+ Sbjct: 293 VRWRKDDGELPKSRYEIRDDHTLKIRKVTAG-----DMGSYTCVAENMVGKAEASATLTV 347 Query: 924 DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGM-------DHREII 976 VK + G+TV +C+ + + ++ + Sbjct: 348 QEPPHFVVK--PRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRF 405 Query: 977 QEGRXXXXXXXXXXXXDVGVIKC----IVKDQETSTMLVVKETI----PEFIRK--LQDF 1026 + DVG C + T L V + I P IR+ + Sbjct: 406 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465 Query: 1027 EVKEKDVAILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGE 1086 + + V S ++W +DG ++ + ++ + G L IR + D G Sbjct: 466 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG---VLQIRYAKLGDTGR 522 Query: 1087 YSCI 1090 Y+CI Sbjct: 523 YTCI 526 Score = 77.4 bits (182), Expect = 4e-12 Identities = 108/462 (23%), Positives = 184/462 (39%), Gaps = 56/462 (12%) Query: 1338 IDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM-NVTILDKPSPPGKPNILEI--DS 1394 I + L I +DAG Y N G + E+ +T+L++PS +P+ L + D Sbjct: 218 ITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDD 277 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRA 1453 S+ C E G+ V +++ D S I T I+ + + Sbjct: 278 SAEFKC----EARGDPVP---TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTC 330 Query: 1454 YAVNEVDISDASETTEYYKVIKETKIQSPT--VEKPLKNITTEPNEDIELTCIFGGVPQP 1511 A N V ++AS T +Q P V KP + + C G PQP Sbjct: 331 VAENMVGKAEASATLT---------VQEPPHFVVKPRDQVVAL-GRTVTFQCEATGNPQP 380 Query: 1512 KVTWYRDGKK---------LKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 + W R+G + +++ + Y C N G + T Sbjct: 381 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITK 440 Query: 1563 CVVG----IQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKE 1618 + I +P I + Q V ++++ V G P P ++W K+G L + ++ Sbjct: 441 AYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDG-VLVSTQD 499 Query: 1619 YNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYD-----KPSKPEGPV 1673 I E V++I+ K + +YT AS +G ++ ++V + +P +P P Sbjct: 500 SRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPN 558 Query: 1674 I---------MREISRESVTIEWKPPLDDGGLELTKYAIEK-HEPDNNRWIKVADVDRDV 1723 + + ++SR +VT+ W+P L+ G T Y IE + W VA+ + Sbjct: 559 LIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSSWQTVAE-NVKT 616 Query: 1724 ETYCIQKLNENCEYMFRVIAQNPVGFSEALE-SEPIVIKTAL 1764 ET I+ L N Y+F V A N G S+ + S+P+ + L Sbjct: 617 ETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL 658 Score = 70.5 bits (165), Expect = 5e-10 Identities = 98/408 (24%), Positives = 157/408 (38%), Gaps = 39/408 (9%) Query: 1006 TSTMLVVKETIPEFIRKLQDFEVKEKDVAILEVEINSE-TADVVWERDGEIIKPKKNKYD 1064 T + L ++ P + D V + + A L + T + W + GE ++ K+ Sbjct: 57 TGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 116 Query: 1065 FEKR----GHIRKLYIRN--TSVHDEGEYSCILRDE-----SCTAEVTVVELPPEIITRL 1113 + G + L I + S DEG Y C+ R+ S A + V L + Sbjct: 117 SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP 176 Query: 1114 QNQKVNKGNKATFEIELTKG--DALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLD 1171 + V G A E + +G + + W KDGS + + ++TI G K L I Sbjct: 177 SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDE-RITIRGGK--LMITYTRKS 233 Query: 1172 DAGEYSCEVGN------SKCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIPDETL 1225 DAG+Y C N S+ + +E PS ++ P + V + A E + + Sbjct: 234 DAGKYVCVGTNMVGERESEVAELTVLERPSF---VKRPSNLAVTVDDSAEFKCEARGDPV 290 Query: 1226 DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEV-V 1284 ++K ++ + D TL IRK T D YTCV + + + V Sbjct: 291 PTVRWRKDDGELPKSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347 Query: 1285 EFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK--- 1341 + PP V R+ + G VT + PQP W + P S+ Sbjct: 348 QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSV 407 Query: 1342 --SASLTIKKVENTDAGIYKLRLENNCG----HADVEMNVTILDKPSP 1383 + LTI V+ +D G Y + N G A +E+ I D+P P Sbjct: 408 SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPP 455 Score = 70.5 bits (165), Expect = 5e-10 Identities = 71/274 (25%), Positives = 112/274 (40%), Gaps = 14/274 (5%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM-Y 691 PP F KP+ Q V G + +C P+P I W +G + + S + Sbjct: 350 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEPLKSMIVRQG 749 L ITNV++ G Y +N G L++ ++ PP + + + V Sbjct: 410 TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 469 Query: 750 ESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAEN 809 + +LS G+P PTI W K+ V ++ + + ++ K+ D G YT A Sbjct: 470 GTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIAST 529 Query: 810 SEGIAETSAVITVEEPTEENAEP-PLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYR 868 G A SA I V+E P P N K + V V+RN V +++W Sbjct: 530 PSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPE-----VTDVSRNTV-TLSWQP 583 Query: 869 N-NEIISPSETITQNF---DGENIELVITNVDSE 898 N N +P+ I + F G + + V NV +E Sbjct: 584 NLNSGATPTSYIIEAFSHASGSSWQTVAENVKTE 617 Score = 68.9 bits (161), Expect = 1e-09 Identities = 122/538 (22%), Positives = 207/538 (38%), Gaps = 59/538 (10%) Query: 731 EKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTH--- 787 E PP+++E +IV +GE L+ + G P PTI W K + V+ K D +H Sbjct: 64 EDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVET--DKDDPRSHRML 121 Query: 788 ----SITILK----PKKVKDEGVYTLKAENSEGIAET-SAVITVEEPTEENAEPPLFINR 838 S+ L+ K DEGVY A N G A + +A + V ++ + P + Sbjct: 122 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDV-- 179 Query: 839 FQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSE 898 + V E ++ +P P+I+W ++ SP + + +L+IT + Sbjct: 180 --MVAVGEPAVME-CQPPRGHPEPTISWKKDG---SPLDDKDERITIRGGKLMIT-YTRK 232 Query: 899 IDSGDYKCVASNSAG-KSSHGARVTIDVEKVTFVKHLQK-SYETEEGKTVILECQTSHTV 956 D+G Y CV +N G + S A +T+ +E+ +FVK + ++ E + Sbjct: 233 SDAGKYVCVGTNMVGERESEVAELTV-LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVP 291 Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQ----ETSTMLVV 1012 + +W + E+ EI + D+G C+ ++ E S L V Sbjct: 292 TVRWRKDDGELP-KSRYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETADVV-WERDGE-----IIKPKKNKYDFE 1066 +E P F+ K +D V + E + W R+G +P ++ F Sbjct: 348 QEP-PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFS 406 Query: 1067 KRGHIRKLYIRNTSVHDEGEYSCILRD------ESCTAEVT--VVELPPEIITR-LQNQK 1117 L I N D G Y C + EVT + + PP +I + NQ Sbjct: 407 V-SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465 Query: 1118 VNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEY 1176 V T + W KDG + S + L+I L D G Y Sbjct: 466 VAVDGTFVLSCVATGSPVPTILWRKDG--VLVSTQDSRIKQLENGVLQIRYAKLGDTGRY 523 Query: 1177 SC----EVGNSKCTAILTVEEPSINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTW 1229 +C G + +A + V+E + P + L+P+ ++ T+ ++W Sbjct: 524 TCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSW 581 Score = 58.4 bits (135), Expect = 2e-06 Identities = 109/502 (21%), Positives = 192/502 (38%), Gaps = 58/502 (11%) Query: 1104 ELPPEIITRLQNQKVNKGNKATFEIELT-KGDALVRWFKDGSEIQFS-----NHIQLTID 1157 + PP I+ + V+KG AT + + + W+K G ++ +H L Sbjct: 65 DFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPS 124 Query: 1158 GKKQKLKIYDC--DLDDAGEYSCEVGNSKCTAI---LTVEEPSINFTLRL-PEFILVPAN 1211 G L+I D G Y C N A+ ++E + R P ++V Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVG 184 Query: 1212 TDAYLTVEIPDETLD--VTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCV 1269 A + + P + ++W K S ++D ++ I K L+I + D +Y CV Sbjct: 185 EPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK---LMITYTRKSDAGKYVCV 241 Query: 1270 LLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAF--------PQPNDEW 1321 + + EV E + ER +KR S++ + VD A P P W Sbjct: 242 --GTNMVGERESEVAE----LTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRW 295 Query: 1322 IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP 1381 + + K ++ +L I+KV D G Y EN G A+ +T+ + P Sbjct: 296 RKDDGELPKSRYEIRD----DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPP 351 Query: 1382 SPPGKPNILEIDSSSINICWDEPENTGN-STIIYY--------VVEYQEIDTTEWISVKN 1432 KP ++ + + + + E TGN I++ + YQ ++ SV Sbjct: 352 HFVVKPRD-QVVALGRTVTF-QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ 409 Query: 1433 I-TKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTV--EKPLK 1489 T T++Q +++ Y Y ++++ + T Y +V + P V + P+ Sbjct: 410 TGDLTITNVQ--RSDVGY----YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV- 462 Query: 1490 NITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYE--NRXXXXXXXXXXXXXXX 1547 N T + L+C+ G P P + W +DG + T + + Sbjct: 463 NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGR 522 Query: 1548 YKCIAFNDHGEVETSCVVGIQQ 1569 Y CIA GE S + +Q+ Sbjct: 523 YTCIASTPSGEATWSAYIEVQE 544 Score = 50.0 bits (114), Expect = 7e-04 Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 5/94 (5%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLV 569 P FV++ + +F+C+ G P P + W + + P +++ DD+ TL Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYEIR--DDH--TLK 316 Query: 570 IREVFPEDAGTFTCVAKNAAGFASSTTELIVEAP 603 IR+V D G++TCVA+N G A ++ L V+ P Sbjct: 317 IRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 350 Score = 48.8 bits (111), Expect = 0.002 Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 3/89 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIE-FKTVKGKSWTKIVTVGGSVHE 1924 PS P V++ + +VTL W +P N G+ T+YIIE F G SW + V Sbjct: 561 PSAPSKPEVTDVSRNTVTLSW-QPNLNSGATPTSYIIEAFSHASGSSW-QTVAENVKTET 618 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTE 1953 I+ +K +F + A N G+S P++ Sbjct: 619 SAIKGLKPNAIYLFLVRAANAYGISDPSQ 647 Score = 48.0 bits (109), Expect = 0.003 Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 38/238 (15%) Query: 510 PIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTA-----IIKPSQDFQMYYDDDN 564 P FV K R + G TV F+C+ G P+P I W R+ + +P Q + Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQS-SSRFSVSQ 409 Query: 565 VATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXX 624 L I V D G + C N AG +I +A L E+T Sbjct: 410 TGDLTITNVQRSDVGYYICQTLNVAG------SIITKAYL-----EVTDV---------- 448 Query: 625 XADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAI 684 I + PP + P Q V +L C P P I W G + ++ + Sbjct: 449 ---IADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQL 505 Query: 685 ESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKT--GEKEPPQVIEP 740 E+ VL+I K G YT +A GEA+ ++++ +PP+ +P Sbjct: 506 EN------GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDP 557 Score = 46.8 bits (106), Expect = 0.007 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 4/97 (4%) Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNI-AIRDVTKTMWMEVGKVDVNT 2023 +PS P+ P E+ V N V SW P + GA Y I A + + W V + +V T Sbjct: 560 IPSAPSKP-EVTDVSRNTVTLSW-QPNLNSGATPTSYIIEAFSHASGSSWQTVAE-NVKT 616 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 I+ L N Y+ + A N G+S+P + +P K Sbjct: 617 ETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVK 653 Score = 41.9 bits (94), Expect = 0.19 Identities = 40/174 (22%), Positives = 64/174 (36%), Gaps = 13/174 (7%) Query: 1507 GVPQPKVTWYRDGKKL--KTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCV 1564 G P+P ++W +DG L K + T Y C+ N GE E+ Sbjct: 196 GHPEPTISWKKDGSPLDDKDERITIRG-GKLMITYTRKSDAGKYVCVGTNMVGERESEVA 254 Query: 1565 -VGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITT 1623 + + ++P ++ V D G P P V W K+ +L + Y I Sbjct: 255 ELTVLERPSFVKRPSNLAV--TVDDSAEFKCEARGDPVPTVRWRKDDGELPKSR-YEI-- 309 Query: 1624 KEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS---KPEGPVI 1674 ++I+++ YT A N G + TL V + P KP V+ Sbjct: 310 -RDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVV 362 >UniRef50_Q4SAP1 Cluster: Chromosome undetermined SCAF14681, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14681, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1751 Score = 89.8 bits (213), Expect = 7e-16 Identities = 91/362 (25%), Positives = 150/362 (41%), Gaps = 24/362 (6%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T V G P P V W L + + I +V+ + ++++S + YT A +T Sbjct: 25 ITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR----NVLELTDVRQS--ANYTCVAMSTL 78 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G + V P P PV+ E + S+T+ W D G E Y I +H+ + Sbjct: 79 GVIEAMAQITVKALPKAPGTPVVT-ERTATSITLTW----DSGNPEPVSYYIIQHKSKYS 133 Query: 1712 RWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 + ++D T Y + L+ +Y FRV+A N +G SE I KTA PS Sbjct: 134 DDL-YKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIG--RGPPSEIIEAKTAEQAPSTA 190 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827 + + + I W E+ G + + Y ++ Q W+ IQ Sbjct: 191 PRQVRGHMMSSTTAVIHWDEPEEANGQIMGYRVYYTMDSSQHVNLWEKQIVRGSKFVTIQ 250 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 L N TY ++ A +G P + D +I I KT P SQP +F + S+ L W Sbjct: 251 GLIPNKTYYIKVLAYTSVGDG-PLSPDLQI-ITKTGVP-SQPTDFKAEAKSETSILLSWI 307 Query: 1888 EPESNG-GSPITNYIIEFKTVKGKSWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTV 1946 P G + IT Y + ++ +I + + ++++K FR++A + Sbjct: 308 APAQTGQENQITGYELVYRKSDDTEEKRISFEPTTT--YLLKDLKPFTTYTFRLAARSKH 365 Query: 1947 GV 1948 GV Sbjct: 366 GV 367 Score = 60.9 bits (141), Expect = 4e-07 Identities = 66/289 (22%), Positives = 116/289 (40%), Gaps = 20/289 (6%) Query: 1618 EYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMRE 1677 EY+ +T+ + + I +L+ + T+ A T G + + + PE P +M Sbjct: 502 EYDDSTEHE---MIITDLQAETTYSVTVAAYTTKGDGARSKPKLITTTGAVPEKPRLMVS 558 Query: 1678 ISRESVTI-EWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCE 1736 + + +W PP G L Y + D + + +R+ Y +++++ Sbjct: 559 TTNMGTALLQWHPPAITHG-PLQGYRLRFGRKDMDPLTVIEFPERE-NHYTTKEIHKGAS 616 Query: 1737 YMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFP---SEK 1793 Y FR+ A+N VGF E E + T DVPS ++ ++W P +E+ Sbjct: 617 YTFRLSARNKVGFGEETVKE---VSTNEDVPSGYPQSITAEGATTSTIQVSWQPVLLTER 673 Query: 1794 NGGSPIIDYKV---EIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIGTSLP 1850 NG II Y + +I + + L +TTY ++ A G+ P Sbjct: 674 NG--KIIKYALQYKDINSPRSPSELFITAPESTVILDGLKADTTYDIKMCAFTSKGSG-P 730 Query: 1851 YTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEPES-NGGSPIT 1898 Y+ + + L +NF V + SV L W P++ N P T Sbjct: 731 YSPSVQFRT-QPLDQAVFAKNFHVKAAMKSSVLLTWEIPDTYNPAQPFT 778 Score = 51.6 bits (118), Expect = 2e-04 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 12/185 (6%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+ + I G V + P P +W++ ++ + P D Sbjct: 5 PPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNV 58 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 ++ + + Y + G + +T+ P PG P + E ++SI + WD Sbjct: 59 LELTDVRQSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTWD---- 114 Query: 1407 TGN-STIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 +GN + YY+++++ + + + + + T+ S+ L S Y FR A+N + Sbjct: 115 SGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPP 174 Query: 1465 SETTE 1469 SE E Sbjct: 175 SEIIE 179 Score = 50.0 bits (114), Expect = 7e-04 Identities = 62/274 (22%), Positives = 106/274 (38%), Gaps = 21/274 (7%) Query: 1783 SVYITWFPSEKNGGSPIIDYKVEIKQEGKK--WKXXXXXXXXXARIQKLSINTTYQFRIY 1840 S+ +TW + P+ Y ++ K + +K + LS + Y+FR+ Sbjct: 108 SITLTW---DSGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVV 164 Query: 1841 ARNEIGTSLPYTSDDKITIGKT-LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITN 1899 A N IG P + T + T P Q R ++S +T+ + W EPE G I Sbjct: 165 AINNIGRGPPSEIIEAKTAEQAPSTAPRQVRGHMMSSTTA---VIHWDEPEEANGQ-IMG 220 Query: 1900 YIIEFKTVKGKS---WTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTESQS 1956 Y + + + W K + G I+ + ++ A +VG P S Sbjct: 221 YRVYYTMDSSQHVNLWEKQIVRGSKFVT--IQGLIPNKTYYIKVLAYTSVGDG-PL-SPD 276 Query: 1957 VRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGA-PLLGYNIAIRDVTKTMWME 2015 +++ VPS PT + ++ SW P G + GY + R T Sbjct: 277 LQIITKTGVPSQPT-DFKAEAKSETSILLSWIAPAQTGQENQITGYELVYRKSDDTEEKR 335 Query: 2016 VGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGL 2049 + T + ++DL TY R+ AR++ G+ Sbjct: 336 ISFEPTTT--YLLKDLKPFTTYTFRLAARSKHGV 367 Score = 46.8 bits (106), Expect = 0.007 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 20/135 (14%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP FS P + G + + C V P P + W+ E++ P E DM + Sbjct: 4 VPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIG 55 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749 +VL++T+V+ Q YT VA++ G + +K K P P V E + I Sbjct: 56 RNVLELTDVR--QSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTW 113 Query: 750 ESVILSAQVVGNPRP 764 +S GNP P Sbjct: 114 DS--------GNPEP 120 Score = 46.0 bits (104), Expect = 0.011 Identities = 73/360 (20%), Positives = 132/360 (36%), Gaps = 20/360 (5%) Query: 1495 PNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN 1554 P + +TC+ G P P V W + L R Y C+A + Sbjct: 19 PGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR--NVLELTDVRQSANYTCVAMS 76 Query: 1555 DHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 G +E + ++ P + ++ +T + P V +Y +K + Sbjct: 77 TLGVIEAMAQITVKALPKAP-GTPVVTERTATS----ITLTWDSGNPEPVSYYIIQHKSK 131 Query: 1615 -NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS--SVEVTLKVYDK-PSKPE 1670 +D Y T+ + L ++ + A N G S + K ++ PS Sbjct: 132 YSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPPSEIIEAKTAEQAPSTAP 191 Query: 1671 GPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV--ADVDRDVETYCI 1728 V +S + I W P + G ++ Y + + D+++ + + + R + I Sbjct: 192 RQVRGHMMSSTTAVIHWDEPEEANG-QIMGYRV-YYTMDSSQHVNLWEKQIVRGSKFVTI 249 Query: 1729 QKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITW 1788 Q L N Y +V+A VG I+ KT VPS + S+ ++W Sbjct: 250 QGLIPNKTYYIKVLAYTSVGDGPLSPDLQIITKTG--VPSQPTDFKAEAKSET-SILLSW 306 Query: 1789 F-PSEKNGGSPIIDYK-VEIKQEGKKWKXXXXXXXXXARIQKLSINTTYQFRIYARNEIG 1846 P++ + I Y+ V K + + K ++ L TTY FR+ AR++ G Sbjct: 307 IAPAQTGQENQITGYELVYRKSDDTEEKRISFEPTTTYLLKDLKPFTTYTFRLAARSKHG 366 Score = 37.1 bits (82), Expect = 5.3 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSVRLEKHATVPSPPTAPLEIRMVGSNI 1982 H++ +EN+ + E ++A VG + Q VR E+ VPS P +E+ + S+ Sbjct: 396 HQYLLENLDKFTEYRVSVTAHTDVGAGPESPPQLVRTEED--VPSGPPRKVEVEALNSSS 453 Query: 1983 VMTSWGTP 1990 + W +P Sbjct: 454 IKVIWRSP 461 >UniRef50_Q4S5S6 Cluster: Chromosome 9 SCAF14729, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF14729, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1238 Score = 89.8 bits (213), Expect = 7e-16 Identities = 101/434 (23%), Positives = 175/434 (40%), Gaps = 35/434 (8%) Query: 628 ILEGIPPTFSKKPKAQ--YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIE 685 ++E P S K + V G ++LLEC +P P I W GE++V + Sbjct: 240 VVESAPTWLSPKGSSSSTLVLLGEELLLECIAAGVPTPHITWRKDGEDLVVRSPVKA--- 296 Query: 686 SDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMI 745 + +++I G Y A N+ I +++K P +E ++ Sbjct: 297 ---KNFNKMIQIPRASFEDAGEYVCTATNKLDYIQHTITVQVKAA----PFWLEKPADLV 349 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT-ILKPKKVKDEGVYT 804 + E L + G PRPT+TW N +P+ + + + T +L+ + VY Sbjct: 350 LAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTVTTLNNAVYQ 409 Query: 805 LKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSI 864 A N G +A + V +A P + +R + + V E L R +PVP + Sbjct: 410 CNASNPYGYLLANAFVNV-----LHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPEL 464 Query: 865 TWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTID 924 W + + + +G L I N+ +D G Y CV SN AG+ + +V I+ Sbjct: 465 RWSKYGQGSLEGNRFRTHSNG---TLEIKNI-QVVDQGAYLCVVSNVAGRDEN--QVRIE 518 Query: 925 VEKVTFVKHLQKSYETEEGKTVILEC--QTSHT--VSTKWYHNKKEISGMDHREIIQEGR 980 V++ T + + G V EC +T T V+T W K ++ + R + E Sbjct: 519 VKEPTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPVT-LGWRISMDESN 577 Query: 981 XXXXXXXXXXXXDVGVIKCIVK---DQETSTMLVVKETIPEFIRKLQDFEVKEKDVAILE 1037 D G C+VK +Q++++ ++ P+ L+ + E+ V + Sbjct: 578 ---LVISNINTADGGNYTCLVKSELEQKSASARLMVMDRPDPPTDLELSDPHERSVRLSW 634 Query: 1038 VEINSETADVVWER 1051 V NS + ER Sbjct: 635 VPGNSHHNPITGER 648 Score = 55.6 bits (128), Expect = 1e-05 Identities = 48/206 (23%), Positives = 77/206 (37%), Gaps = 7/206 (3%) Query: 1484 VEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKL--KTAKATYE-NRXXXXXXXX 1540 +EKP ++ P ED L C G P+P VTW+ +G+ + T + E + Sbjct: 342 LEKPA-DLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPSTLQPNVEVSGETVVLRTV 400 Query: 1541 XXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIP 1600 Y+C A N +G + + V + + + + K G + G P Sbjct: 401 TTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSP 460 Query: 1601 PPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTL 1660 PE+ W K G + E N + IK ++ Y SN AG +V + Sbjct: 461 VPELRWSKYG---QGSLEGNRFRTHSNGTLEIKNIQVVDQGAYLCVVSNVAGRDENQVRI 517 Query: 1661 KVYDKPSKPEGPVIMREISRESVTIE 1686 +V + P M+ I V E Sbjct: 518 EVKEPTLIVTRPTDMKVIRGADVRFE 543 Score = 48.8 bits (111), Expect = 0.002 Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 9/160 (5%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKL---KTAKATYENRXXXXXXXXXXXXXXXYKCIAF 1553 E++ L CI GVP P +TW +DG+ L KA N+ Y C A Sbjct: 263 EELLLECIAAGVPTPHITWRKDGEDLVVRSPVKAKNFNK-MIQIPRASFEDAGEYVCTAT 321 Query: 1554 NDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKL 1613 N ++ + V ++ P D+ + ++ + +G P P V W+ NG + Sbjct: 322 NKLDYIQHTITVQVKAAPFWLEKPADLVLAPE--EDGRLVCRSDGAPRPTVTWFINGEPI 379 Query: 1614 E-NDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAG 1652 + + + N+ +T V+R + +++ Y ASN G Sbjct: 380 DPSTLQPNVEVSGETVVLR--TVTTLNNAVYQCNASNPYG 417 Score = 48.8 bits (111), Expect = 0.002 Identities = 55/262 (20%), Positives = 98/262 (37%), Gaps = 12/262 (4%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN--SKCTAILTVEEP 1194 + W KDG ++ + ++ K ++I +DAGEY C N +TV+ Sbjct: 279 ITWRKDGEDLVVRSPVKAKNFNKM--IQIPRASFEDAGEYVCTATNKLDYIQHTITVQVK 336 Query: 1195 SINFTLRLP-EFILVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTLISDVKKRTL 1253 + F L P + +L P + VTW+ I D +V T+ Sbjct: 337 AAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPI-DPSTLQPNVEVSGETV 395 Query: 1254 IIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREY-RIKRGSDVTLLVD 1310 ++R T + Y C + V V+ P+I+ EY ++ GS L Sbjct: 396 VLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSRAFLDCR 455 Query: 1311 YQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHAD 1370 Y P P W SK + + +L IK ++ D G Y + N G + Sbjct: 456 YFGSPVPELRW---SKYGQGSLEGNRFRTHSNGTLEIKNIQVVDQGAYLCVVSNVAGRDE 512 Query: 1371 VEMNVTILDKPSPPGKPNILEI 1392 ++ + + + +P +++ Sbjct: 513 NQVRIEVKEPTLIVTRPTDMKV 534 Score = 48.0 bits (109), Expect = 0.003 Identities = 75/384 (19%), Positives = 147/384 (38%), Gaps = 30/384 (7%) Query: 1044 TADVVWERDGE--IIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCTAEVT 1101 T + W +DGE +++ +F K + I S D GEY C ++ + T Sbjct: 276 TPHITWRKDGEDLVVRSPVKAKNFNKM-----IQIPRASFEDAGEYVCTATNKLDYIQHT 330 Query: 1102 V---VELPPEIITRLQNQKVNKGNKATFEIELTKGDA-LVRWFKDGSEIQFSNHIQLTID 1157 + V+ P + + + + V WF +G I S +Q ++ Sbjct: 331 ITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDPST-LQPNVE 389 Query: 1158 GKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLRL----PEFILVPANTD 1213 + + + + Y C N + ++ T R+ E++ V + Sbjct: 390 VSGETVVLRTVTTLNNAVYQCNASNPYGYLLANAFVNVLHATPRILGSRNEYLKVIEGSR 449 Query: 1214 AYLTVEIPDETL-DVTWYKKKSVIEDTEKFTLISDVKKRTLIIRKCTEDDQCEYTCVLLD 1272 A+L + ++ W K + +F S+ TL I+ DQ Y CV+ + Sbjct: 450 AFLDCRYFGSPVPELRWSKYGQGSLEGNRFRTHSN---GTLEIKNIQVVDQGAYLCVVSN 506 Query: 1273 A--KSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTL--LVDYQAFPQPNDEWIVNSKII 1328 + ++++EV E P IV + ++ RG+DV V A W+ +K + Sbjct: 507 VAGRDENQVRIEVKE-PTLIVTRPTDMKVIRGADVRFECAVKTDATTPVTTTWMKGTKPV 565 Query: 1329 KKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPN 1388 + S+D ++L I + D G Y +++ + ++D+P PP Sbjct: 566 TL--GWRISMDE--SNLVISNINTADGGNYTCLVKSELEQKSASARLMVMDRPDPPTDLE 621 Query: 1389 ILEIDSSSINICWDEPENTGNSTI 1412 + + S+ + W P N+ ++ I Sbjct: 622 LSDPHERSVRLSW-VPGNSHHNPI 644 Score = 44.0 bits (99), Expect = 0.046 Identities = 47/202 (23%), Positives = 81/202 (40%), Gaps = 16/202 (7%) Query: 627 DILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIES 686 ++L P + + V EGS L+CR P P++ W G+ + E S Sbjct: 426 NVLHATPRILGSRNEYLKVIEGSRAFLDCRYFGSPVPELRWSKYGQGSL--EGNRFRTHS 483 Query: 687 DMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIV 746 + L+I N++ +G Y V N G + +++ KEP ++ M V Sbjct: 484 N-----GTLEIKNIQVVDQGAYLCVVSNVAGRDENQVRIEV----KEPTLIVTRPTDMKV 534 Query: 747 RQGESVILSAQVVGNPRP--TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT 804 +G V V + T TW K KPV L + D ++ ++ D G YT Sbjct: 535 IRGADVRFECAVKTDATTPVTTTWMKGTKPV-TLGWRISMDESNL-VISNINTADGGNYT 592 Query: 805 -LKAENSEGIAETSAVITVEEP 825 L E + ++ ++ ++ P Sbjct: 593 CLVKSELEQKSASARLMVMDRP 614 Score = 43.6 bits (98), Expect = 0.061 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 12/141 (8%) Query: 633 PPTFSKKPKAQYVDEGSD-ILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 PPT K+ +++ + D +++EC P P +W G N++ ++ M + Sbjct: 2 PPTIIKQSMKEHIVDAKDAMVIECEAKGNPHPIFSWRRNGRYY----NVARDPQASMRRH 57 Query: 692 CSVLKI--TNVKKFQEGTYTVVAVNREGEA-SLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 L I N + E Y VA N G A S I L++ P ++IEP +++ Sbjct: 58 SGTLDIYARNNPEQYEAEYQCVASNMYGSAYSNKIRLRLYRAPVWPREIIEP---VVISA 114 Query: 749 GESVILSAQ-VVGNPRPTITW 768 G ++LS G P+P W Sbjct: 115 GLPLVLSCDPPPGPPKPETYW 135 Score = 38.7 bits (86), Expect = 1.7 Identities = 47/196 (23%), Positives = 74/196 (37%), Gaps = 15/196 (7%) Query: 1833 TTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP--E 1890 T Y+FR+ A NEIG S P + P P+N + ++ + W EP Sbjct: 707 TYYEFRVIAINEIGMSRPSRPSSRFQ-SSGAPPDVIPKNLKGVGTWRNNMEISW-EPLAY 764 Query: 1891 SNGGSPITNYIIEFKTVKGK-SWTKIVTVGGSVHEHCIENIKEKDEIIFRISAENTVGV- 1948 + P Y++ +K + W T + + + D ++ A N G+ Sbjct: 765 KDWNGPHLKYLVWWKRKDSREEWKNATTRWSKYYIYGADTFTPYD---LKVQAVNDFGMG 821 Query: 1949 --SLPTESQSVRLEKHATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDG-GAPLLGYNI 2003 S S A P P TAPL +R+ + SN V W D L Y + Sbjct: 822 PESPIVTGFSGEDLSDAFSPGPLTAPLNLRVSDIESNQVTVHWDPVSHDSIMGELKEYKV 881 Query: 2004 AI-RDVTKTMWMEVGK 2018 RD ++ W+ V + Sbjct: 882 YYWRDSSQLRWLRVNR 897 Score = 37.1 bits (82), Expect = 5.3 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 2/99 (2%) Query: 493 DKLPVFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKP 552 +KL + + + AP ++EK + C+ +G PRP +TWF I P Sbjct: 322 NKLDYIQHTITVQVKAAPFWLEKPADLVLAPEEDGRLVCRSDGAPRPTVTWFINGEPIDP 381 Query: 553 SQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGF 591 S Q + T+V+R V + + C A N G+ Sbjct: 382 S-TLQPNVEVSG-ETVVLRTVTTLNNAVYQCNASNPYGY 418 >UniRef50_UPI0000E47478 Cluster: PREDICTED: similar to hemicentin, partial; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to hemicentin, partial - Strongylocentrotus purpuratus Length = 1839 Score = 89.4 bits (212), Expect = 9e-16 Identities = 79/334 (23%), Positives = 132/334 (39%), Gaps = 28/334 (8%) Query: 597 ELIVEA-PLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLEC 655 EL++ A SD G+ V +E P F P + G + +EC Sbjct: 1316 ELVISAVENSDEGTYTCVASNSGGDDEFSTVVTVESAP-YFPYPPSDESKRPGESVDIEC 1374 Query: 656 RLVAIPEPDIAWLFKGE-----EIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 R +P P + W G+ E D + D + + + ITN++ + Sbjct: 1375 RSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGDPQL--ATISITNLQTTDSNVFQC 1432 Query: 711 VAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVG---------- 760 +A N E +VL + + P + + V Q +S + V G Sbjct: 1433 IATNMYKEELTSVVLNVFSIPASIPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISV 1492 Query: 761 -NPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAV 819 +P P ITW + + +++ S + ++ ++ DEG YT A N+ G E S V Sbjct: 1493 LDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVASNTGGDDEFSTV 1552 Query: 820 ITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETI 879 +TVE PP + + + I E+ + L R T P P+ W ++ + + Sbjct: 1553 VTVEYDV-----PPSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSND 1607 Query: 880 TQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 + DG N LVI ++ + D G Y+C A N G Sbjct: 1608 RVSLDGGN--LVIESL-TTADDGQYQCFAKNRLG 1638 Score = 81.0 bits (191), Expect = 3e-13 Identities = 122/558 (21%), Positives = 209/558 (37%), Gaps = 67/558 (12%) Query: 628 ILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESD 687 +L+ PP+ ++P++ D+ + L CR + PEP W G D N +++ Sbjct: 509 LLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG- 567 Query: 688 MHMYCSVLKITNVKKFQEGTYTVVAVNR----EGEASLPIVLKIKTGEKEPPQVIEPLKS 743 L I ++ +G Y A NR + E + P ++++ G +PLK Sbjct: 568 -----GNLVIESLTTADDGQYQCFANNRLVMEQFENTAPAMVQLSQG--------QPLK- 613 Query: 744 MIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP--TKSDGDTHSITILKPKKVKD-E 800 +R G S + GNP P I W + ++ + + D + D + Sbjct: 614 --LRCGGSPGIPN---GNPAPLIYWTDASPKHTSITYNARINQDLEGNLVFSNIIASDAK 668 Query: 801 GVYTLKAENSEGIAETS--AVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTR 858 G Y L N G+ + S +++V + + L + + KL Sbjct: 669 GYYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFG 728 Query: 859 NPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHG 918 P P ITW R E + ++ G+ LVI+ V++ D G Y CVASN+ G Sbjct: 729 YPTPVITWKRGEEQLQSGGRVSIEESGQ--ALVISAVENS-DEGTYTCVASNTGGDDEFS 785 Query: 919 ARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT--VSTKWYHNKKE----ISGMDH 972 VT VE + G++V +EC++ + +W N + S +D Sbjct: 786 TVVT--VESAPYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDT 843 Query: 973 RE---IIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVK 1029 + + + D V +CI ++ + V + F ++ F Sbjct: 844 ERWTVVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPL 903 Query: 1030 EKDVAILEVEI--------NSETADVVWERDGEIIKPKKNKYDF-EKRGHIRKLYIRNTS 1080 + ++++E + + W G ++ KY E G L I N Sbjct: 904 TRRLSVVEDDSAKFICHSRGRPDPTITWTFKGSVL-TNGIKYTINETEG---SLVINNVK 959 Query: 1081 VHDEGEYSCIL------RDESCTAEVTVVEL-PPEIITRLQNQKVNKGNKATFEIELTKG 1133 D GEY C D T T+ L I N + +GN ATF+ E+T Sbjct: 960 KVDGGEYECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYD 1019 Query: 1134 DALVR----WFKDGSEIQ 1147 + L+ W KDG ++ Sbjct: 1020 EELIEPYVYWMKDGQRLE 1037 Score = 75.4 bits (177), Expect = 2e-11 Identities = 83/324 (25%), Positives = 127/324 (39%), Gaps = 38/324 (11%) Query: 661 PEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEAS 720 P P I W E++ +S+ H + L I+ V+ EGTYT VA N G+ Sbjct: 1291 PTPVITWKRGEEQLQSGGRVSI------HEH--ELVISAVENSDEGTYTCVASNSGGDDE 1342 Query: 721 LPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPT 780 V+ +++ P P R GESV + + G P PT+ W N +P + Sbjct: 1343 FSTVVTVESA----PYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFES 1398 Query: 781 KSD--------GDTHSITI-LKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAE 831 D GD TI + + D V+ A N TS V+ V A Sbjct: 1399 NRDTERWEVVTGDPQLATISITNLQTTDSNVFQCIATNMYKEELTSVVLNVFSIP---AS 1455 Query: 832 PPLFINRFQEITVKEKGTIKLVARV-----------TRNPVPSITWYRNNEIISPSETIT 880 P F ++++V + + K V +P P ITW R E + ++ Sbjct: 1456 IPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVS 1515 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKHLQKSYET 940 G+ ELVI + D G Y CVASN+ G VT++ + + +S Sbjct: 1516 IQEFGQ--ELVIFAFEIS-DEGTYTCVASNTGGDDEFSTVVTVEYDVPPSIVEQPESING 1572 Query: 941 EEGKTVILECQTSHTVSTKWYHNK 964 +E + L C+ + T +Y K Sbjct: 1573 DERIPLTLTCRATGTPEPTYYWEK 1596 Score = 67.3 bits (157), Expect = 4e-09 Identities = 96/445 (21%), Positives = 171/445 (38%), Gaps = 44/445 (9%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF---RQTAIIKPSQD---FQMYYDD 562 AP F + G +V EC+ EG P P + WF + A + ++D +++ D Sbjct: 1352 APYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGD 1411 Query: 563 DNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXX 622 +AT+ I + D+ F C+A N + T +++ Sbjct: 1412 PQLATISITNLQTTDSNVFQCIATNM--YKEELTSVVLNV-------------FSIPASI 1456 Query: 623 XXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISV 682 + + + K EG + + V P P I W E++ +S+ Sbjct: 1457 PSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKISVLDPTPVITWKRGEEQLQSGGRVSI 1516 Query: 683 AIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLK 742 E + +I++ EGTYT VA N G+ V+ ++ PP ++E + Sbjct: 1517 Q-EFGQELVIFAFEISD-----EGTYTCVASNTGGDDEFSTVVTVEYDV--PPSIVEQPE 1568 Query: 743 SMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT----ILKPKKVK 798 S+ + + L+ + G P PT W K+ AL D S+ +++ Sbjct: 1569 SINGDERIPLTLTCRATGTPEPTYYWEKDG----ALFNVDSNDRVSLDGGNLVIESLTTA 1624 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTE--ENAEPP-LFINRFQEITVKEKGTIKLVAR 855 D+G Y A+N G A + ++T + EN EP + +++ Q + ++ G+ + Sbjct: 1625 DDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENIEPARIQVSQGQPLKLRCGGSPGVP-- 1682 Query: 856 VTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 P P I W +P + LV +NV + G Y +N G S Sbjct: 1683 -NGTPAPLIYWTDATPKPTPITYNARINQDPQGNLVFSNVIASDAKGYYCQAINNVVGSS 1741 Query: 916 SHGARVTIDVEKVTFVKH-LQKSYE 939 +VT+ V + H L + +E Sbjct: 1742 QRSPKVTLRVRVDACLGHTLDQGWE 1766 Score = 65.7 bits (153), Expect = 1e-08 Identities = 81/332 (24%), Positives = 131/332 (39%), Gaps = 32/332 (9%) Query: 629 LEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDM 688 + +PP+ ++P++ D+ + L CR IPEP W G D N +++ Sbjct: 27 IHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDGGN 86 Query: 689 HMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIE--PLKSMIV 746 L I ++ +G Y A NR ++ + + E QV + PLK + Sbjct: 87 ------LVIESLTTADDGQYQCFANNRL------VMDQFENTAWETIQVDQGRPLK---L 131 Query: 747 RQGESVILSAQVVGNPRPTITW---CKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 R G S + GNP P + W P+ S S+ +G Y Sbjct: 132 RCGGSPGVPN---GNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYY 188 Query: 804 TLKAENSEGIAETSAVITV---EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNP 860 N G ++ S +T+ + P ++ + EI ++ + + KL P Sbjct: 189 CQAINNVVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQ-SFKLKCIAYGYP 247 Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 P ITW R E + I+ G+ ELVI+ V++ D G Y CVASN G Sbjct: 248 TPEITWKRGEEQLQSGGRISIEESGQ--ELVISTVENS-DKGTYTCVASNCEGIDEFSTV 304 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQT 952 VT VE + G++V +EC++ Sbjct: 305 VT--VESAPYFPAPPSDETKRPGESVDIECRS 334 Score = 62.9 bits (146), Expect = 9e-08 Identities = 95/432 (21%), Positives = 157/432 (36%), Gaps = 36/432 (8%) Query: 1254 IIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQA 1313 ++ T D + V++ A T L + +FPP IV+ + +TL Sbjct: 484 VVGSPTSDARALEKSVVIAATDTRTL---LDDFPPSIVEQPESVTGDQRIPLTLTCRAIG 540 Query: 1314 FPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEM 1373 P+P W + + + + S+D +L I+ + D G Y+ N E Sbjct: 541 TPEPAYYWEKDGALFDMDSNDRASLDG--GNLVIESLTTADDGQYQCFANNRLVMEQFEN 598 Query: 1374 NVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV-VEYQEIDTTEWISVKN 1432 + + S G+P L S N + +IY+ + T + Sbjct: 599 TAPAMVQLSQ-GQPLKLRCGGSP------GIPNGNPAPLIYWTDASPKHTSITYNARINQ 651 Query: 1433 ITKTQTSIQNLKTNSSYRFRAYAVNEV-DISDAS-----ETTEYYKVIKETKIQSPTVEK 1486 + N+ + + + A+N V + S T+ V + S Sbjct: 652 DLEGNLVFSNIIASDAKGYYCLAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAAS 711 Query: 1487 PLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXX 1544 + N T + +L CI G P P +TW R ++L++ + E+ Sbjct: 712 EVANRT----QSFKLKCIAFGYPTPVITWKRGEEQLQSGGRVSIEESGQALVISAVENSD 767 Query: 1545 XXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEV 1604 Y C+A N G+ E S VV ++ P D K K G+ + EG+PPP V Sbjct: 768 EGTYTCVASNTGGDDEFSTVVTVESAPYFLAPPSD-KTKGP-GESVDIECRSEGVPPPTV 825 Query: 1605 IWYKNGNKLENDKEYNITTKEKTSV--------IRIKELKRSHSSKYTIEASNTAGTSSV 1656 W NG D E NI T+ T V I I L+ + S+ + A+N Sbjct: 826 EWLVNGQTWA-DFESNIDTERWTVVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELT 884 Query: 1657 EVTLKVYDKPSK 1668 V L V P++ Sbjct: 885 SVVLNVVSFPAR 896 Score = 62.5 bits (145), Expect = 1e-07 Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 19/183 (10%) Query: 737 VIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKK 796 V +P S I + +S L G P P ITW + + +++ S ++ ++ + Sbjct: 222 VTKPAASEIAIRTQSFKLKCIAYGYPTPEITWKRGEEQLQSGGRISIEESGQELVISTVE 281 Query: 797 VKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARV 856 D+G YT A N EGI E S V+TVE A P + T + ++ + R Sbjct: 282 NSDKGTYTCVASNCEGIDEFSTVVTVESAPYFPAPP-------SDETKRPGESVDIECRS 334 Query: 857 TRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSS 916 P P++T N + + +ET +G LVI NV ++DSG+Y+C A N+ Sbjct: 335 KGVPAPTLT---NRDKYTVNET-----EG---SLVINNV-KKVDSGEYECRAENAIDGDD 382 Query: 917 HGA 919 H A Sbjct: 383 HEA 385 Score = 56.0 bits (129), Expect = 1e-05 Identities = 152/708 (21%), Positives = 261/708 (36%), Gaps = 93/708 (13%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--- 790 PP ++E +S+ Q + L+ + +G P P W K+ AL D S+ Sbjct: 514 PPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDG----ALFDMDSNDRASLDGGN 569 Query: 791 -ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 +++ D+G Y A N V E E A + +++ Q + ++ G+ Sbjct: 570 LVIESLTTADDGQYQCFANNR----------LVMEQFENTAPAMVQLSQGQPLKLRCGGS 619 Query: 850 IKLVARVTRNPVPSITWYR---NNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC 906 + NP P I W + I+ + I Q+ +G LV +N+ + D+ Y C Sbjct: 620 PGIP---NGNPAPLIYWTDASPKHTSITYNARINQDLEGN---LVFSNIIAS-DAKGYYC 672 Query: 907 VASNSA-GKSSHGARVTI---DVEKVTFVKHLQKSYETEE----GKTVILECQTSH--TV 956 +A N+ G ++ + D+ V HL E ++ L+C T Sbjct: 673 LAINNVVGLFQRSPKIMLSVTDLPAVASAAHLDSHPAASEVANRTQSFKLKCIAFGYPTP 732 Query: 957 STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKCIVK----DQETSTMLVV 1012 W ++++ I + G+ D G C+ D E ST++ V Sbjct: 733 VITWKRGEEQLQSGGRVSIEESGQALVISAVENS--DEGTYTCVASNTGGDDEFSTVVTV 790 Query: 1013 KETIPEFIRKLQDFEVKEKDVAILEVEINSETAD---VVWERDGEIIKPKKNKYDFEK-- 1067 E+ P F+ D + K ++ ++E SE V W +G+ ++ D E+ Sbjct: 791 -ESAPYFLAPPSD-KTKGPGESV-DIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWT 847 Query: 1068 ----RGHIRKLYIRNTSVHDEGEYSCIL----RDESCTAEVTVVELPPEI--ITRLQNQ- 1116 + + I N D + CI ++E + + VV P I T L + Sbjct: 848 VVTGDPQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRL 907 Query: 1117 KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 V + + A F + D + W GS + +N I+ TI+ + L I + D GE Sbjct: 908 SVVEDDSAKFICHSRGRPDPTITWTFKGSVL--TNGIKYTINETEGSLVINNVKKVDGGE 965 Query: 1176 YSCEVGNS------KCTAILTVEEPSINFTLRLPEFILVPANTDAYLTVEIP-DETL--- 1225 Y C N+ + T T+ P +++ A EI DE L Sbjct: 966 YECRAENAIDGEDYEATGSATLTMLGKTTIYLSPANLMIREGNTATFQCEITYDEELIEP 1025 Query: 1226 DVTWYKKKSVIEDTE-------KFTL----ISDVKKRTLIIRKCTEDDQCEYTCVLLDAK 1274 V W K +E + +F ++ R I R E Q LL Sbjct: 1026 YVYWMKDGQRLEANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEG 1085 Query: 1275 ST----TKLKVEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKK 1330 T T+ + + PP IV+ + +TL P+P W + + Sbjct: 1086 RTRAHDTRRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNV 1145 Query: 1331 CKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTIL 1378 + + S+D +L IK + D G Y+ +N G A + +T L Sbjct: 1146 DSNDRVSLD--GGNLVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSL 1191 Score = 55.2 bits (127), Expect = 2e-05 Identities = 65/273 (23%), Positives = 102/273 (37%), Gaps = 25/273 (9%) Query: 655 CRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVN 714 C P+P I W FKG + I I L I NVKK G Y A N Sbjct: 919 CHSRGRPDPTITWTFKGSVLT--NGIKYTINETE----GSLVINNVKKVDGGEYECRAEN 972 Query: 715 R-EGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR---PTITWCK 770 +GE T + + P MI R+G + ++ + P + W K Sbjct: 973 AIDGEDYEATGSATLTMLGKTTIYLSPANLMI-REGNTATFQCEITYDEELIEPYVYWMK 1031 Query: 771 NNKPVKALPTKSDGDTHSITILKP-------KKVKDEGVYTLKAENSEGI---AETSAVI 820 + + ++A G + L P + + V ++A EG+ T A Sbjct: 1032 DGQRLEANQFLDSGGVRFMRCLPPLATSASRESISRSIVEAIQAAGPEGLLPEGRTRAHD 1091 Query: 821 TVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETIT 880 T N PP + + + I ++ + L R T P P+ W ++ + + Sbjct: 1092 T-RRYIGYNDVPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1150 Query: 881 QNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 + DG N LVI ++ + D G Y+C A N G Sbjct: 1151 VSLDGGN--LVIKSL-TTADDGQYQCFAKNRLG 1180 Score = 54.0 bits (124), Expect = 4e-05 Identities = 78/334 (23%), Positives = 122/334 (36%), Gaps = 34/334 (10%) Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKP-NILEIDSSSINI-CWD 1402 L I VEN+D G Y N+ G + VT+ P P P + + S++I C Sbjct: 1317 LVISAVENSDEGTYTCVASNSGGDDEFSTVVTVESAPYFPYPPSDESKRPGESVDIEC-- 1374 Query: 1403 EPENTGNSTIIYYV-----VEYQ-EIDTTEWISVKNITKTQT-SIQNLKTNSSYRFRAYA 1455 E T+ ++V +++ DT W V + T SI NL+T S F+ A Sbjct: 1375 RSEGVPAPTVDWFVNGQPWADFESNRDTERWEVVTGDPQLATISITNLQTTDSNVFQCIA 1434 Query: 1456 VNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGG-------- 1507 N E T + P+ + ++ N+ + TC G Sbjct: 1435 TNMY----KEELTSVVLNVFSIPASIPSFTPLTRKLSVVQNDSAKFTCHVEGRPLPIIKI 1490 Query: 1508 ---VPQPKVTWYRDGKKLKTA--KATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETS 1562 P P +TW R ++L++ + E Y C+A N G+ E S Sbjct: 1491 SVLDPTPVITWKRGEEQLQSGGRVSIQEFGQELVIFAFEISDEGTYTCVASNTGGDDEFS 1550 Query: 1563 CVVGIQQ--KPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 VV ++ P I E I ++ +T G P P W K+G D Sbjct: 1551 TVVTVEYDVPPSIVEQPESINGDERI--PLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1608 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTS 1654 ++ V I+ L + +Y A N GT+ Sbjct: 1609 VSLDGGNLV--IESLTTADDGQYQCFAKNRLGTA 1640 Score = 52.4 bits (120), Expect = 1e-04 Identities = 50/158 (31%), Positives = 72/158 (45%), Gaps = 19/158 (12%) Query: 653 LECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVA 712 L+C P P+I W E++ IS+ ES L I+ V+ +GTYT VA Sbjct: 239 LKCIAYGYPTPEITWKRGEEQLQSGGRISIE-ESGQE-----LVISTVENSDKGTYTCVA 292 Query: 713 VNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNN 772 N EG V+ +++ P P R GESV + + G P PT+T N Sbjct: 293 SNCEGIDEFSTVVTVESA----PYFPAPPSDETKRPGESVDIECRSKGVPAPTLT----N 344 Query: 773 KPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENS 810 + K +++G S+ I KKV D G Y +AEN+ Sbjct: 345 RD-KYTVNETEG---SLVINNVKKV-DSGEYECRAENA 377 Score = 51.2 bits (117), Expect = 3e-04 Identities = 78/385 (20%), Positives = 135/385 (35%), Gaps = 29/385 (7%) Query: 1281 VEVVEFPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDS 1340 V + + PP IV+ + +TL P+P W + + + + S+D Sbjct: 25 VPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGSLFDVDSNDRASLDG 84 Query: 1341 KSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINIC 1400 +L I+ + D G Y+ NN D N G+P L S Sbjct: 85 --GNLVIESLTTADDGQYQC-FANNRLVMDQFENTAWETIQVDQGRPLKLRCGGSP---- 137 Query: 1401 WDEPENTGNSTIIYYVVEYQEIDTTEWISVKNITKTQTSI--QNLKTNSSYRFRAYAVNE 1458 P GN + Y + T + + + S+ N+ + + + A+N Sbjct: 138 -GVPN--GNPAPLMYWTDAAAKPTPISYNARISQDPEGSLVFSNVIASDAKGYYCQAINN 194 Query: 1459 V--DISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWY 1516 V + + T + + V KP + + +L CI G P P++TW Sbjct: 195 VVGSSQQSPKVTLMVSDLPAVDSGASLVTKPAASEIAIRTQSFKLKCIAYGYPTPEITWK 254 Query: 1517 RDGKKLKTAK--ATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVIT 1574 R ++L++ + E+ Y C+A N G E S VV ++ P Sbjct: 255 RGEEQLQSGGRISIEESGQELVISTVENSDKGTYTCVASNCEGIDEFSTVVTVESAPYFP 314 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKE 1634 D + + G+ + +G+P P L N +Y + E + V I Sbjct: 315 APPSD--ETKRPGESVDIECRSKGVPAP---------TLTNRDKYTVNETEGSLV--INN 361 Query: 1635 LKRSHSSKYTIEASNTAGTSSVEVT 1659 +K+ S +Y A N E T Sbjct: 362 VKKVDSGEYECRAENAIDGDDHEAT 386 Score = 48.4 bits (110), Expect = 0.002 Identities = 42/192 (21%), Positives = 70/192 (36%), Gaps = 15/192 (7%) Query: 1481 SPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENR-------- 1532 +P P + T P E +++ C GVP P V W +G+ ++ + Sbjct: 793 APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGD 852 Query: 1533 ---XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQKHKVGDE 1589 ++CIA N + E TS V+ + P S + ++ V ++ Sbjct: 853 PQLATIAITNLQTTDSNVFQCIATNKYKEELTSVVLNVVSFPARITSFTPLTRRLSVVED 912 Query: 1590 WLVTAVIE--GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEA 1647 + G P P + W G+ L N +Y I E + V I +K+ +Y A Sbjct: 913 DSAKFICHSRGRPDPTITWTFKGSVLTNGIKYTINETEGSLV--INNVKKVDGGEYECRA 970 Query: 1648 SNTAGTSSVEVT 1659 N E T Sbjct: 971 ENAIDGEDYEAT 982 Score = 46.0 bits (104), Expect = 0.011 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + +C GYP P+ITW R ++ + +++ LVI V D GT+TCVA N Sbjct: 238 KLKCIAYGYPTPEITWKRGEEQLQSGGRISI---EESGQELVISTVENSDKGTYTCVASN 294 Query: 588 AAGFASSTTELIVEA 602 G +T + VE+ Sbjct: 295 CEGIDEFSTVVTVES 309 Score = 45.6 bits (103), Expect = 0.015 Identities = 70/296 (23%), Positives = 110/296 (37%), Gaps = 26/296 (8%) Query: 1337 SIDSKSASLTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDKP---SPPGKPNILEID 1393 SI+ +L I VEN+D G Y N G + VT+ P +PP + Sbjct: 750 SIEESGQALVISAVENSDEGTYTCVASNTGGDDEFSTVVTVESAPYFLAPPSDKTKGPGE 809 Query: 1394 SSSINICWDEPENTGNSTIIYYV-----VEYQ-EIDTTEWISVKNITKTQT-SIQNLKTN 1446 S I C E T+ + V +++ IDT W V + T +I NL+T Sbjct: 810 SVDIE-C--RSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGDPQLATIAITNLQTT 866 Query: 1447 SSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFG 1506 S F+ A N+ E T + + + + ++ ++ + C Sbjct: 867 DSNVFQCIATNKY----KEELTSVVLNVVSFPARITSFTPLTRRLSVVEDDSAKFICHSR 922 Query: 1507 GVPQPKVTWYRDGKKLKTA-KATY-ENRXXXXXXXXXXXXXXXYKCIAFN----DHGEVE 1560 G P P +TW G L K T E Y+C A N + E Sbjct: 923 GRPDPTITWTFKGSVLTNGIKYTINETEGSLVINNVKKVDGGEYECRAENAIDGEDYEAT 982 Query: 1561 TSCVVGIQQKPVITIS--NEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLE 1614 S + + K I +S N I++ + + +T E + P V W K+G +LE Sbjct: 983 GSATLTMLGKTTIYLSPANLMIREGNTATFQCEIT-YDEELIEPYVYWMKDGQRLE 1037 Score = 43.6 bits (98), Expect = 0.061 Identities = 27/145 (18%), Positives = 59/145 (40%), Gaps = 3/145 (2%) Query: 766 ITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEP 825 + +C+ + L + I+ P + GV ++ + ++ + + Sbjct: 448 LDFCQARYDIHCLDPGPSKGAIGLPIISPHRRMKAGVVGSPTSDARALEKSVVIAATDTR 507 Query: 826 TEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDG 885 T + PP + + + +T ++ + L R P P+ W ++ + + DG Sbjct: 508 TLLDDFPPSIVEQPESVTGDQRIPLTLTCRAIGTPEPAYYWEKDGALFDMDSNDRASLDG 567 Query: 886 ENIELVITNVDSEIDSGDYKCVASN 910 N LVI ++ + D G Y+C A+N Sbjct: 568 GN--LVIESL-TTADDGQYQCFANN 589 Score = 43.6 bits (98), Expect = 0.061 Identities = 47/194 (24%), Positives = 72/194 (37%), Gaps = 13/194 (6%) Query: 1600 PPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVT 1659 P P + W + +L++ +I E + I ++ S YT ASN+ G Sbjct: 1291 PTPVITWKRGEEQLQSGGRVSIHEHE----LVISAVENSDEGTYTCVASNSGGDDEFSTV 1346 Query: 1660 LKVYDKPSKPEGPVIMREISRESVTIEWK-----PPLDDGGLELTKYAIEKHEPDNNRWI 1714 + V P P P + ESV IE + P D + +A + D RW Sbjct: 1347 VTVESAPYFPYPPSDESKRPGESVDIECRSEGVPAPTVDWFVNGQPWADFESNRDTERW- 1405 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQNPVGFSEALESEPI-VIKTALDVPSXXXXX 1773 +V D + T I L +F+ IA N + E L S + V +PS Sbjct: 1406 EVVTGDPQLATISITNLQTTDSNVFQCIATNM--YKEELTSVVLNVFSIPASIPSFTPLT 1463 Query: 1774 XXXXXIDNESVYIT 1787 + N+S T Sbjct: 1464 RKLSVVQNDSAKFT 1477 Score = 43.2 bits (97), Expect = 0.081 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 528 QFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKN 587 + +C GYP P ITW R ++ + +++ LVI V D GT+TCVA N Sbjct: 721 KLKCIAFGYPTPVITWKRGEEQLQSGGRVSI---EESGQALVISAVENSDEGTYTCVASN 777 Query: 588 AAGFASSTTELIVEA 602 G +T + VE+ Sbjct: 778 TGGDDEFSTVVTVES 792 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 4/99 (4%) Query: 813 IAETSAVITVEEPTEENAE-PPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNE 871 I E I ++PT + PP + + + I ++ + L R T P P+ W ++ Sbjct: 11 IVEQPESINGDQPTVPIHDVPPSIVEQPESINGDQRIPLTLTCRATGIPEPTYYWEKDGS 70 Query: 872 IISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASN 910 + + DG N LVI ++ + D G Y+C A+N Sbjct: 71 LFDVDSNDRASLDGGN--LVIESL-TTADDGQYQCFANN 106 Score = 39.5 bits (88), Expect = 0.99 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 6/85 (7%) Query: 509 APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWF--RQT-AIIKPSQDFQMY---YDD 562 AP F+ K G +V EC+ EG P P + W QT A + + D + + D Sbjct: 793 APYFLAPPSDKTKGPGESVDIECRSEGVPPPTVEWLVNGQTWADFESNIDTERWTVVTGD 852 Query: 563 DNVATLVIREVFPEDAGTFTCVAKN 587 +AT+ I + D+ F C+A N Sbjct: 853 PQLATIAITNLQTTDSNVFQCIATN 877 Score = 39.1 bits (87), Expect = 1.3 Identities = 25/97 (25%), Positives = 39/97 (40%), Gaps = 3/97 (3%) Query: 498 FEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQ 557 F + E + P VE+ + + + C+ G P P W + A+ + + Sbjct: 1549 FSTVVTVEYDVPPSIVEQPESINGDERIPLTLTCRATGTPEPTYYWEKDGALFNVDSNDR 1608 Query: 558 MYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 + D N LVI + D G + C AKN G A S Sbjct: 1609 VSLDGGN---LVIESLTTADDGQYQCFAKNRLGTAMS 1642 Score = 38.3 bits (85), Expect = 2.3 Identities = 25/89 (28%), Positives = 37/89 (41%), Gaps = 2/89 (2%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVE 1657 G P PE+ W + +L++ +I +E + I ++ S YT ASN G Sbjct: 245 GYPTPEITWKRGEEQLQSGGRISI--EESGQELVISTVENSDKGTYTCVASNCEGIDEFS 302 Query: 1658 VTLKVYDKPSKPEGPVIMREISRESVTIE 1686 + V P P P + ESV IE Sbjct: 303 TVVTVESAPYFPAPPSDETKRPGESVDIE 331 Score = 38.3 bits (85), Expect = 2.3 Identities = 53/208 (25%), Positives = 86/208 (41%), Gaps = 23/208 (11%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT--- 790 PP ++E +S+ Q + L+ + G P PT W K+ AL D S+ Sbjct: 1102 PPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDG----ALFNVDSNDRVSLDGGN 1157 Query: 791 -ILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTE--ENAEPP-LFINRFQEITVKE 846 ++K D+G Y A+N G A + ++T + EN EP + + R + + + Sbjct: 1158 LVIKSLTTADDGQYQCFAKNRLGTAMSQKILTSLAFMDQFENTEPAWIQVRRGRPLKLLC 1217 Query: 847 KGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNF----DGENIELVITNVDSEIDSG 902 G+ + NP P I W N P+ IT N D E LV ++ + D+ Sbjct: 1218 GGSPGI---PNGNPAPLIYW--TNAAAKPT-PITYNARIAQDPEG-NLVFSHAIAS-DAQ 1269 Query: 903 DYKCVASNSAGKSSHGARVTIDVEKVTF 930 Y C A N+ SS + +T+ Sbjct: 1270 GYYCQAINNIVGSSQRTPIISPTPVITW 1297 Score = 37.1 bits (82), Expect = 5.3 Identities = 41/153 (26%), Positives = 62/153 (40%), Gaps = 15/153 (9%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP+ ++P++ D+ + L CR PEP W G D N V+++ Sbjct: 1101 VPPSIVEQPESINGDQRVPLTLTCRATGTPEPTYYWEKDGALFNVDSNDRVSLDG----- 1155 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGES 751 L I ++ +G Y A NR G A +L + + EP + VR+G Sbjct: 1156 -GNLVIKSLTTADDGQYQCFAKNRLGTAMSQKIL-TSLAFMDQFENTEP-AWIQVRRGRP 1212 Query: 752 VIL----SAQVV-GNPRPTITWCKNNKPVKALP 779 + L S + GNP P I W N K P Sbjct: 1213 LKLLCGGSPGIPNGNPAPLIYW--TNAAAKPTP 1243 Score = 36.7 bits (81), Expect = 7.0 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 531 CQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAG 590 C+ G P P W + A+ + ++ D N LVI+ + D G + C AKN G Sbjct: 1124 CRATGTPEPTYYWEKDGALFNVDSNDRVSLDGGN---LVIKSLTTADDGQYQCFAKNRLG 1180 Query: 591 FASS 594 A S Sbjct: 1181 TAMS 1184 >UniRef50_UPI00015A6655 Cluster: myomesin family, member 3; n=6; Danio rerio|Rep: myomesin family, member 3 - Danio rerio Length = 1172 Score = 89.4 bits (212), Expect = 9e-16 Identities = 91/395 (23%), Positives = 154/395 (38%), Gaps = 46/395 (11%) Query: 1603 EVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKV 1662 +V WY++G + + T +++ + +K + + H YT+ GT VE + V Sbjct: 39 DVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHEGLYTVRLRTWDGT--VEHSAYV 96 Query: 1663 YDKPSK------PEGPVIMR--EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWI 1714 Y K P P+ ++ +++R+ V + W PP DG + Y IE+ + +W Sbjct: 97 YVKDGSAVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWE 156 Query: 1715 KVADVDRDVETYCIQKLNENCEYMFRVIAQN------------PVGFSEALE-SEPIVIK 1761 + DV + V Y + L EN Y FRV A N P+ S+ LE S +V+K Sbjct: 157 RCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVK 216 Query: 1762 TA---------------LDVPSXXXXXXXXXXIDNESVYITWFPSEKNGGSPIIDYKVEI 1806 + VP D +V + W + G P+ Y VE Sbjct: 217 VERGRQIVITKDQLEGQIRVPFPPTEVQVCELSDTYAV-LRWTEPDPRGREPL-KYFVER 274 Query: 1807 KQEG-KKWKXXXXXXXXXA-RIQKLSINT--TYQFRIYARNEIGTSLPYTSDDKITIGKT 1862 G + W + R +Y +R+ + N+ G S P I++G+ Sbjct: 275 SISGTESWHLASMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQP 334 Query: 1863 LTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSV 1922 P+ P + T+ SV L+W EP G I Y + W I + Sbjct: 335 QGVPAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITT 392 Query: 1923 HEHCIENIKEKDEIIFRISAENTVGVSLPTESQSV 1957 ++ +K + +FR+ + G S+ +E V Sbjct: 393 TRFTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPV 427 Score = 75.4 bits (177), Expect = 2e-11 Identities = 69/296 (23%), Positives = 120/296 (40%), Gaps = 38/296 (12%) Query: 1779 IDNESVYITWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXAR--IQKLSINTTY 1835 ++ + V+++W P +G + + Y +E G KW+ + + L NT Y Sbjct: 120 VNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMY 179 Query: 1836 QFRIYARNEIGTSLP-------YTSDD---------KITIGKTLT-----------PPSQ 1868 QFR+ A N+ G P TSD K+ G+ + P Sbjct: 180 QFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVKVERGRQIVITKDQLEGQIRVPFP 239 Query: 1869 PRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSW--TKIVTVGGSVHEHC 1926 P V E + L+WTEP+ G P+ Y +E +SW + S Sbjct: 240 PTEVQVCELSDTYAVLRWTEPDPRGREPL-KYFVERSISGTESWHLASMDMTVLSTRFSA 298 Query: 1927 IENIKEKDEIIFRISAENTVGVSLPT-ESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMT 1985 + K K +R+ + N G+S P+ S+ + L + VP+PP+ L +R S++++ Sbjct: 299 FDQQKGK-SYSYRVRSVNKYGISEPSLPSKPISLGQPQGVPAPPSGVLPMRDTNSSVLL- 356 Query: 1986 SWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRI 2041 W P G ++GY + + W + + T +F + L N Y+ R+ Sbjct: 357 QWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRFTVDGLKSNKQYVFRV 410 Score = 63.3 bits (147), Expect = 7e-08 Identities = 27/83 (32%), Positives = 44/83 (53%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T ++G P PE+ W KN ++ + +YNI + K+S + I + S Y+I N Sbjct: 1088 LTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSMEDSGNYSIFVRNKH 1147 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVI 1674 G+ +V VT+ VY KP G + Sbjct: 1148 GSQTVLVTVSVYKHGEKPRGDAV 1170 Score = 57.6 bits (133), Expect = 4e-06 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 16/185 (8%) Query: 1299 IKRGSDVTLLVDYQAFPQPNDE---WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA 1355 +K G ++ L + P + W + ++ + +SASLT+K V Sbjct: 17 VKEGDNLVLQCSFTTALLPFQQDVTWYRDGLAVRPSSRVELQTALRSASLTVKHVHKEHE 76 Query: 1356 GIYKLRLENNCGHADVEMNVTILDKPS----PPGKPNILEIDSSSIN-----ICWDEPEN 1406 G+Y +RL G + V + D + PG P L++ S +N + W P Sbjct: 77 GLYTVRLRTWDGTVEHSAYVYVKDGSAVVVGAPGSP--LQVKCSDVNRDYVFLSWIPPSA 134 Query: 1407 TGNSTIIYYVVEYQEIDTTEWISVKNITKT--QTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 G + + Y +E +I +W ++ + Q + LK N+ Y+FR AVN+ + Sbjct: 135 DGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQYPVMGLKENTMYQFRVCAVNQAGVGRP 194 Query: 1465 SETTE 1469 S+ +E Sbjct: 195 SKPSE 199 Score = 53.6 bits (123), Expect = 6e-05 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 2/98 (2%) Query: 1963 ATVPSPPTAPLEIRM--VGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVD 2020 A V P +PL+++ V + V SW P DG A + GY I D+ W V Sbjct: 103 AVVVGAPGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVI 162 Query: 2021 VNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEP 2058 ++ + L EN Y R+ A N+ G+ P + EP Sbjct: 163 QKVCQYPVMGLKENTMYQFRVCAVNQAGVGRPSKPSEP 200 Score = 48.4 bits (110), Expect = 0.002 Identities = 49/231 (21%), Positives = 91/231 (39%), Gaps = 33/231 (14%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTVGGSVHEH 1925 P P S+ V L W P ++G + + Y IE + W + V V ++ Sbjct: 109 PGSPLQVKCSDVNRDYVFLSWIPPSADGAAAVQGYFIERCDIGVGKWERCNDVIQKVCQY 168 Query: 1926 CIENIKEKDEIIFRISAENTVGVSLPTE---------------SQSVRLEKHATV----- 1965 + +KE FR+ A N GV P++ + V++E+ + Sbjct: 169 PVMGLKENTMYQFRVCAVNQAGVGRPSKPSEPIMTSDPLEPSRTMVVKVERGRQIVITKD 228 Query: 1966 --------PSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG 2017 P PPT +++ + + W P+ G PL + R ++ T + Sbjct: 229 QLEGQIRVPFPPT-EVQVCELSDTYAVLRWTEPDPRGREPLKYF--VERSISGTESWHLA 285 Query: 2018 KVDVNTL--KFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFKVIPGEG 2066 +D+ L +F+ D + +Y R+ + N+ G+SEP +P + +G Sbjct: 286 SMDMTVLSTRFSAFDQQKGKSYSYRVRSVNKYGISEPSLPSKPISLGQPQG 336 Score = 42.3 bits (95), Expect = 0.14 Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 4/95 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN--ITKTQT 1438 P+PP + +SS+ + W EP T I+ Y + E + +W ++ N IT T+ Sbjct: 338 PAPPSGVLPMRDTNSSVLLQWKEPAVTEG--IVGYYLYCSEAGSGQWKTINNKPITTTRF 395 Query: 1439 SIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKV 1473 ++ LK+N Y FR +V S SE + +V Sbjct: 396 TVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRV 430 Score = 41.9 bits (94), Expect = 0.19 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 4/101 (3%) Query: 1666 PSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVET 1725 P+ P G + MR+ + SV ++WK P G+ Y + E + +W + + Sbjct: 338 PAPPSGVLPMRD-TNSSVLLQWKEPAVTEGI--VGYYLYCSEAGSGQWKTINNKPITTTR 394 Query: 1726 YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIV-IKTALD 1765 + + L N +Y+FRV + G S E P++ +K AL+ Sbjct: 395 FTVDGLKSNKQYVFRVKSVGVSGNSIYSEESPVIRVKAALN 435 Score = 37.9 bits (84), Expect = 3.0 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW-ISVKNIT--KTQ 1437 P PP + + E+ + + W EP+ G + Y+ VE T W ++ ++T T+ Sbjct: 237 PFPPTEVQVCELSDTYAVLRWTEPDPRGREPLKYF-VERSISGTESWHLASMDMTVLSTR 295 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDAS 1465 S + + SY +R +VN+ IS+ S Sbjct: 296 FSAFDQQKGKSYSYRVRSVNKYGISEPS 323 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/107 (21%), Positives = 54/107 (50%), Gaps = 5/107 (4%) Query: 726 KIKTGEKEPPQVIEPLKSMI-VRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TK 781 +++ EK +V + L ++ + + +S+ L+ V G+P P + W KN++ + + K Sbjct: 1059 QVEFAEKNRARVTKGLPDVVAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIK 1118 Query: 782 SDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEE 828 ++ + ++TI ++D G Y++ N G ++V + E+ Sbjct: 1119 NENKSSTLTI-NHVSMEDSGNYSIFVRNKHGSQTVLVTVSVYKHGEK 1164 Score = 37.1 bits (82), Expect = 5.3 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 842 ITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDS 901 + + E ++ L V +P P + W +N+ IS + + ++ L I +V E DS Sbjct: 1078 VAIMEDKSLCLTCFVDGDPAPEMFWMKNDREISSAAQYNIKNENKSSTLTINHVSME-DS 1136 Query: 902 GDYKCVASNSAGKSSHGARVTIDVEK 927 G+Y N G S VT+ V K Sbjct: 1137 GNYSIFVRNKHG--SQTVLVTVSVYK 1160 >UniRef50_A7TAR2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 253 Score = 89.4 bits (212), Expect = 9e-16 Identities = 69/269 (25%), Positives = 119/269 (44%), Gaps = 24/269 (8%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G + CR+ IP+PDI W + G + N++ S ++ V + N ++ EG+ Sbjct: 3 GKNFTFTCRVEGIPKPDIKWKYNGGPL----NLA---HSTINNTLVVFNVQNTDRY-EGS 54 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQVVGNPRPTI 766 Y A +R G AS L + P++ + L K+++ +G +V LS Q G+P P Sbjct: 55 YECEASSRAGNASSSASLTVYA----LPKITKLLNKTLVAERGSNVQLSCQASGDPTPKY 110 Query: 767 TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPT 826 W P+ D + + ILK GVY A N+EG T + V Sbjct: 111 KWTYKGVPISPRENVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIV---- 166 Query: 827 EENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSE----TITQN 882 + + + +++ E + L P+P++TWY ++II+ ++ +IT N Sbjct: 167 --HVSVGIVVPLPEKVIFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNN 224 Query: 883 FDGENIELVITNVDSEI-DSGDYKCVASN 910 G +E + ++ D G+Y CV N Sbjct: 225 VSGVRLESTLRLNNTRFGDRGNYSCVFKN 253 Score = 61.3 bits (142), Expect = 3e-07 Identities = 43/153 (28%), Positives = 70/153 (45%), Gaps = 19/153 (12%) Query: 641 KAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNV 700 K + GS++ L C+ P P W +KG I P EN V +E D + L + V Sbjct: 86 KTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPREN--VQLEDDNRL----LILKKV 139 Query: 701 KKFQEGTYTVVAVNREGE--ASLPIVLKIKTGEKEPPQVIEPL-KSMIVRQGESVILSAQ 757 G Y +A N EG +++ + G ++ PL + +I +G+ + L+ Sbjct: 140 SPVSNGVYRCIAYNAEGNDTTETKLIVHVSVG------IVVPLPEKVIFMEGQPLNLTCA 193 Query: 758 VVGNPRPTITWCKNNKPVKALPTKSDGDTHSIT 790 G P P +TW +K + T++DG +SIT Sbjct: 194 AEGIPLPNVTWYHYDKII----TQTDGSRYSIT 222 Score = 57.2 bits (132), Expect = 5e-06 Identities = 29/77 (37%), Positives = 44/77 (57%), Gaps = 3/77 (3%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 GS VQ CQ G P P+ W + I P ++ Q+ +DDN L++++V P G + C Sbjct: 93 GSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQL--EDDN-RLLILKKVSPVSNGVYRC 149 Query: 584 VAKNAAGFASSTTELIV 600 +A NA G ++ T+LIV Sbjct: 150 IAYNAEGNDTTETKLIV 166 Score = 55.6 bits (128), Expect = 1e-05 Identities = 65/253 (25%), Positives = 104/253 (41%), Gaps = 24/253 (9%) Query: 855 RVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNV-DSEIDSGDYKCVASNSAG 913 RV P P I W N ++ + + N LV+ NV +++ G Y+C AS+ AG Sbjct: 11 RVEGIPKPDIKWKYNGGPLNLAHSTINN------TLVVFNVQNTDRYEGSYECEASSRAG 64 Query: 914 KSSHGARVTI-DVEKVTFVKHLQKSYETEEGKTVILECQTS--HTVSTKWYHNKKEISGM 970 +S A +T+ + K+T K L K+ E G V L CQ S T KW + IS Sbjct: 65 NASSSASLTVYALPKIT--KLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPR 122 Query: 971 DHREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQE----TSTMLVVKETIPEFIRKLQDF 1026 ++ ++ + R GV +CI + E T T L+V ++ + + Sbjct: 123 ENVQLEDDNRLLILKKVSPVSN--GVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKV 180 Query: 1027 EVKEKDVAILEVEINS-ETADVVWERDGEII-KPKKNKYDFEKR-GHIR---KLYIRNTS 1080 E L +V W +II + ++Y +R L + NT Sbjct: 181 IFMEGQPLNLTCAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTR 240 Query: 1081 VHDEGEYSCILRD 1093 D G YSC+ ++ Sbjct: 241 FGDRGNYSCVFKN 253 Score = 50.8 bits (116), Expect = 4e-04 Identities = 37/167 (22%), Positives = 66/167 (39%), Gaps = 8/167 (4%) Query: 1482 PTVEKPL-KNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAKATY--ENRXXXXXX 1538 P + K L K + E +++L+C G P PK W G + + ++ Sbjct: 78 PKITKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDDNRLLILK 137 Query: 1539 XXXXXXXXXYKCIAFNDHGE--VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y+CIA+N G ET +V + V+ + + I + G +T Sbjct: 138 KVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKVIFME---GQPLNLTCAA 194 Query: 1597 EGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 EGIP P V WY + + S +R++ R +++++ Sbjct: 195 EGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRF 241 Score = 48.8 bits (111), Expect = 0.002 Identities = 36/168 (21%), Positives = 69/168 (41%), Gaps = 5/168 (2%) Query: 1497 EDIELTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDH 1556 ++ TC G+P+P + W +G L A +T N Y+C A + Sbjct: 4 KNFTFTCRVEGIPKPDIKWKYNGGPLNLAHSTINNTLVVFNVQNTDRYEGSYECEASSRA 63 Query: 1557 GEVETSCVVGIQQKPVIT-ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLEN 1615 G +S + + P IT + N+ + + G ++ G P P+ W G + + Sbjct: 64 GNASSSASLTVYALPKITKLLNKTLVAER--GSNVQLSCQASGDPTPKYKWTYKGVPI-S 120 Query: 1616 DKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVY 1663 +E N+ ++ ++ +K++ + Y A N G + E L V+ Sbjct: 121 PRE-NVQLEDDNRLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVH 167 Score = 44.4 bits (100), Expect = 0.035 Identities = 57/242 (23%), Positives = 99/242 (40%), Gaps = 22/242 (9%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEV----GNSKCTAILTVE 1192 ++W +G + ++ TI+ + + D + G Y CE GN+ +A LTV Sbjct: 20 IKWKYNGGPLNLAHS---TINNTLVVFNVQNTDRYE-GSYECEASSRAGNASSSASLTVY 75 Query: 1193 E-PSINFTLRLPEFILVPANTDAYLTVEIP-DETLDVTWYKKKSVIEDTEKFTLISDVKK 1250 P I T L + ++ ++ L+ + D T W K I E L D Sbjct: 76 ALPKI--TKLLNKTLVAERGSNVQLSCQASGDPTPKYKWTYKGVPISPRENVQLEDD--N 131 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKS--TTKLKVEVVEFPPKIVDYEREYRIKRGSDVTLL 1308 R LI++K + Y C+ +A+ TT+ K+ V +V + G + L Sbjct: 132 RLLILKKVSPVSNGVYRCIAYNAEGNDTTETKLIVHVSVGIVVPLPEKVIFMEGQPLNLT 191 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIK---KVENT---DAGIYKLRL 1362 + P PN W KII + ++ SI + + + ++ ++ NT D G Y Sbjct: 192 CAAEGIPLPNVTWYHYDKIITQTDGSRYSITNNVSGVRLESTLRLNNTRFGDRGNYSCVF 251 Query: 1363 EN 1364 +N Sbjct: 252 KN 253 Score = 42.3 bits (95), Expect = 0.14 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 4/81 (4%) Query: 1586 VGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTI 1645 VG + T +EGIP P++ W NG L + T V ++ R + Y Sbjct: 2 VGKNFTFTCRVEGIPKPDIKWKYNGGPL---NLAHSTINNTLVVFNVQNTDR-YEGSYEC 57 Query: 1646 EASNTAGTSSVEVTLKVYDKP 1666 EAS+ AG +S +L VY P Sbjct: 58 EASSRAGNASSSASLTVYALP 78 Score = 40.7 bits (91), Expect = 0.43 Identities = 51/222 (22%), Positives = 94/222 (42%), Gaps = 18/222 (8%) Query: 1302 GSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDA--GIYK 1359 G + T + P+P+ +W N + T I++ +L + V+NTD G Y+ Sbjct: 3 GKNFTFTCRVEGIPKPDIKWKYNGGPLNLAHST---INN---TLVVFNVQNTDRYEGSYE 56 Query: 1360 LRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIY-YVVE 1418 + G+A ++T+ P N + N+ + +G+ T Y + + Sbjct: 57 CEASSRAGNASSSASLTVYALPKITKLLNKTLVAERGSNVQLS-CQASGDPTPKYKWTYK 115 Query: 1419 YQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETK 1478 I E + +++ + ++ + S+ +R A N ++ ++TTE K+I Sbjct: 116 GVPISPRENVQLEDDNRLLI-LKKVSPVSNGVYRCIAYN----AEGNDTTET-KLIVHVS 169 Query: 1479 IQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 + V P K I E + + LTC G+P P VTWY K Sbjct: 170 V-GIVVPLPEKVIFME-GQPLNLTCAAEGIPLPNVTWYHYDK 209 Score = 37.1 bits (82), Expect = 5.3 Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 7/71 (9%) Query: 523 DGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNV------ATLVIREVFPE 576 +G + C EG P P +TW+ II + D Y +NV +TL + Sbjct: 184 EGQPLNLTCAAEGIPLPNVTWYHYDKIITQT-DGSRYSITNNVSGVRLESTLRLNNTRFG 242 Query: 577 DAGTFTCVAKN 587 D G ++CV KN Sbjct: 243 DRGNYSCVFKN 253 >UniRef50_UPI0000F2C7E8 Cluster: PREDICTED: similar to myomesin 1; n=1; Monodelphis domestica|Rep: PREDICTED: similar to myomesin 1 - Monodelphis domestica Length = 1245 Score = 89.0 bits (211), Expect = 1e-15 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%) Query: 1861 KTLTPPSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKG---KSWTKIVT 1917 K + PS P + ES S+ L W +PE GG+ IT Y + ++ V G W + Sbjct: 922 KAVAAPSPPYDITCLESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKWKEANI 981 Query: 1918 VGGSVHEHCIENIKEKDEIIFRISAENTVGVSLPTE-SQSVRLEKHA-TVPSPPTAPLEI 1975 S + I N+KE F+++A N GV P++ S S + E+ VP PP L+ Sbjct: 982 KAVSDQAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFKCEEWTIAVPGPPHG-LKY 1040 Query: 1976 RMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRD--VTKTMWMEVGKVDVNTLKFNIRDLSE 2033 V ++ W P + G P+ G+ + +++ W + + + +++L E Sbjct: 1041 SEVRKTSLVLQWKHPVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNTYLKVQNLKE 1100 Query: 2034 NHTYMIRIYARNEIGLSEPLESDEP 2058 +YM R+ A N+ G+ +P + P Sbjct: 1101 GVSYMFRVRALNQAGVGKPSDIAGP 1125 Score = 64.5 bits (150), Expect = 3e-08 Identities = 51/198 (25%), Positives = 79/198 (39%), Gaps = 6/198 (3%) Query: 1866 PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVT-VGGSVHE 1924 P P + V+EST V L W P G I Y +E ++W ++ T + Sbjct: 590 PGPPTDLSVTESTRSYVVLSWKPPGQRGHEGIM-YFVEKCVADTENWQRVNTEIPVKSPR 648 Query: 1925 HCIENIKEKDEIIFRISAENTVGVSLPTESQSVR-LEKHATVPSPPTAPLEIRMVGSNIV 1983 + ++ E FR+ N+ GV P+E+ V + +P P + R +++V Sbjct: 649 FALFDLAEGKSYRFRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDTSVV 708 Query: 1984 MTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNTLKFNIRDLSENHTYMIRIYA 2043 +T W E L+GY I V W V +F L Y+ R+ A Sbjct: 709 VT-W--EESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRA 765 Query: 2044 RNEIGLSEPLESDEPFKV 2061 N GLSE + E +V Sbjct: 766 VNAAGLSEYSQDSEAIEV 783 Score = 57.6 bits (133), Expect = 4e-06 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%) Query: 1669 PEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKV-ADVDRDVETYC 1727 P + + E +R V + WKPP G E Y +EK D W +V ++ + Sbjct: 592 PPTDLSVTESTRSYVVLSWKPP-GQRGHEGIMYFVEKCVADTENWQRVNTEIPVKSPRFA 650 Query: 1728 IQKLNENCEYMFRVIAQNPVGFSEALESEPI-VIKTALDVPSXXXXXXXXXXIDNESVYI 1786 + L E Y FRV N G E E+ + V+ LD+P D SV + Sbjct: 651 LFDLAEGKSYRFRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDT-SVVV 709 Query: 1787 TWFPSEKNGGSPIIDYKVEIKQEGK-KWKXXXXXXXXXARI--QKLSINTTYQFRIYARN 1843 TW E ++ Y +E G +W+ +R L Y FR+ A N Sbjct: 710 TW--EESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRAVN 767 Query: 1844 EIGTSLPYTSDDK 1856 G S Y+ D + Sbjct: 768 AAGLS-EYSQDSE 779 Score = 52.8 bits (121), Expect = 1e-04 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 5/97 (5%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEI---DTTEW--ISVKNITK 1435 PSPP LE S+ + W +PE TG + I Y V Y+E+ +W ++K ++ Sbjct: 927 PSPPYDITCLESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKWKEANIKAVSD 986 Query: 1436 TQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYK 1472 I NLK N Y+F+ AVN + S+ + +K Sbjct: 987 QAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFK 1023 Score = 52.4 bits (120), Expect = 1e-04 Identities = 58/245 (23%), Positives = 94/245 (38%), Gaps = 15/245 (6%) Query: 1617 KEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMR 1676 KE + TT ++ + K + K E + A T K PS P + Sbjct: 879 KEVSETTVQEALAPLAEPQKAADQGKSKSEPAAPA-TLEKGKKKKAVAAPSPPYD-ITCL 936 Query: 1677 EISRESVTIEWKPPLDDGGLELTKYAIEKHEPDN---NRWIKVADVDR-DVETYCIQKLN 1732 E R+S+ + WK P GG E+T Y + E +W K A++ + Y I L Sbjct: 937 ESFRDSMVLGWKQPEKTGGAEITGYYVNYREVIGGVPGKW-KEANIKAVSDQAYKISNLK 995 Query: 1733 ENCEYMFRVIAQNPVGFSEALESEPI--VIKTALDVPSXXXXXXXXXXIDNESVYITWFP 1790 EN Y F+V A N G + + + VP + S+ + W Sbjct: 996 ENMIYQFQVAAVNLAGVGTPSQPSASFKCEEWTIAVPG-PPHGLKYSEVRKTSLVLQWKH 1054 Query: 1791 SEKNGGSPIIDYKVEIKQEGKK---WKXXXXXX--XXXARIQKLSINTTYQFRIYARNEI 1845 +G +P+ + V++K+ K W+ ++Q L +Y FR+ A N+ Sbjct: 1055 PVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNTYLKVQNLKEGVSYMFRVRALNQA 1114 Query: 1846 GTSLP 1850 G P Sbjct: 1115 GVGKP 1119 Score = 48.8 bits (111), Expect = 0.002 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 4/113 (3%) Query: 1951 PTESQSVRLEKHATVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTK 2010 P + + +K PSPP + ++V+ W PE GGA + GY + R+V Sbjct: 912 PATLEKGKKKKAVAAPSPPYDITCLESFRDSMVL-GWKQPEKTGGAEITGYYVNYREVIG 970 Query: 2011 TM---WMEVGKVDVNTLKFNIRDLSENHTYMIRIYARNEIGLSEPLESDEPFK 2060 + W E V+ + I +L EN Y ++ A N G+ P + FK Sbjct: 971 GVPGKWKEANIKAVSDQAYKISNLKENMIYQFQVAAVNLAGVGTPSQPSASFK 1023 Score = 48.8 bits (111), Expect = 0.002 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 10/142 (7%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTE--W--ISVKNITKT 1436 P PP E+ +S+ + W P +G + + + V+ +E + W I+ K I T Sbjct: 1032 PGPPHGLKYSEVRKTSLVLQWKHPVYSGRTPVTGFFVDMKETKAKDDQWRGINEKAIPNT 1091 Query: 1437 QTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPN 1496 +QNLK SY FR A+N+ + S+ ++ ET+ P ++ + N+ + Sbjct: 1092 YLKVQNLKEGVSYMFRVRALNQAGVGKPSDIAG--PIVAETR---PGTKEIVINVDDDGV 1146 Query: 1497 EDIELTCIFGGVPQPKVTWYRD 1518 + C P K W +D Sbjct: 1147 ISLNFECDQMS-PDSKFVWSKD 1167 Score = 45.2 bits (102), Expect = 0.020 Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 4/92 (4%) Query: 1381 PSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEWISVKN---ITKTQ 1437 P PP ++ E S + + W P G+ I+Y+ VE DT W V + + Sbjct: 590 PGPPTDLSVTESTRSYVVLSWKPPGQRGHEGIMYF-VEKCVADTENWQRVNTEIPVKSPR 648 Query: 1438 TSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ +L SYRFR N + + SE T+ Sbjct: 649 FALFDLAEGKSYRFRVRCSNSAGVGEPSEATD 680 Score = 43.6 bits (98), Expect = 0.061 Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 6/114 (5%) Query: 1602 PEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLK 1661 PEV WY+NG + K + + L + YT+ + Sbjct: 351 PEVQWYRNGTLVSPSKWVQTQWSGDRATLTFSHLNKEDEGLYTLRVRMGEYYEQYSAYVF 410 Query: 1662 VYDKPSK----PEGP--VIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPD 1709 V D ++ P P V+ + +++ V I WK P DGG + Y I+K E + Sbjct: 411 VRDADAEIAGAPASPLDVVCLDANKDYVIISWKQPAVDGGSPILGYFIDKEEQE 464 Score = 43.2 bits (97), Expect = 0.081 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Query: 747 RQGESVILSAQVVGNP-----RPTITWCKNN---KPVKALPTKSDGDTHSITILKPKKVK 798 R+GE++ L +VV P +P + W +N P K + T+ GD ++T K + Sbjct: 329 REGETMSLGCRVVITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDRATLTFSHLNK-E 387 Query: 799 DEGVYTLKAENSEGIAETSAVITVEEPTEENAEPP 833 DEG+YTL+ E + SA + V + E A P Sbjct: 388 DEGLYTLRVRMGEYYEQYSAYVFVRDADAEIAGAP 422 Score = 42.3 bits (95), Expect = 0.14 Identities = 35/147 (23%), Positives = 61/147 (41%), Gaps = 10/147 (6%) Query: 1284 VEFPPKI-VDYEREYR-IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSK 1341 + F K V + RE + G V + + + F QP +W N ++ K + Sbjct: 317 IHFDDKFDVSFGREGETMSLGCRVVITPEIKHF-QPEVQWYRNGTLVSPSKWVQTQWSGD 375 Query: 1342 SASLTIKKVENTDAGIYKLRL------ENNCGHADV-EMNVTILDKPSPPGKPNILEIDS 1394 A+LT + D G+Y LR+ E + V + + I P+ P L+ + Sbjct: 376 RATLTFSHLNKEDEGLYTLRVRMGEYYEQYSAYVFVRDADAEIAGAPASPLDVVCLDANK 435 Query: 1395 SSINICWDEPENTGNSTIIYYVVEYQE 1421 + I W +P G S I+ Y ++ +E Sbjct: 436 DYVIISWKQPAVDGGSPILGYFIDKEE 462 Score = 41.1 bits (92), Expect = 0.33 Identities = 52/238 (21%), Positives = 87/238 (36%), Gaps = 26/238 (10%) Query: 488 LNEKIDKLPVFEKPTSEEQSM-APIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQ 546 L + +++ F + +E+ + AP FV K R + V+ C V G+P P++TW++ Sbjct: 168 LRKTLEETEEFHRKLNEDSLLHAPEFVIKPRSHTVWEKQNVRLHCSVSGWPEPRLTWYKN 227 Query: 547 TAII----KPSQ-----DFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTE 597 I P + + M+Y + N T P + N A E Sbjct: 228 HVPINVHANPGKYIIESRYGMHYLEINADTQGPEGKKPNACWGRPPLTANPAAMKGYKGE 287 Query: 598 LIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRL 657 E S M + +I F K + EG + L CR+ Sbjct: 288 -YDETRFHAGASTMPLSFGVTPYGFASKFEI------HFDDKFDVSFGREGETMSLGCRV 340 Query: 658 VAIPE-----PDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGTYTV 710 V PE P++ W G + P + + D + L +++ K EG YT+ Sbjct: 341 VITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDR----ATLTFSHLNKEDEGLYTL 394 Score = 40.3 bits (90), Expect = 0.57 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 3/94 (3%) Query: 1965 VPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVG-KVDVNT 2023 VP PPT L + + V+ SW P G ++ Y + W V ++ V + Sbjct: 589 VPGPPT-DLSVTESTRSYVVLSWKPPGQRGHEGIM-YFVEKCVADTENWQRVNTEIPVKS 646 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPLESDE 2057 +F + DL+E +Y R+ N G+ EP E+ + Sbjct: 647 PRFALFDLAEGKSYRFRVRCSNSAGVGEPSEATD 680 Score = 39.9 bits (89), Expect = 0.75 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%) Query: 1126 FEIELTKGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK- 1184 FE + D+ W KD ++ S +Q+ G K K D +DD G YSC+V ++ Sbjct: 1151 FECDQMSPDSKFVWSKDYVPVEDSPRLQVDTKGNKTKTTFKDLGIDDLGIYSCDVTDTDG 1210 Query: 1185 CTAILTVEEPSINFTLRLPE 1204 A ++E + L L + Sbjct: 1211 IAASYLIDEEEMKRLLALSQ 1230 Score = 38.7 bits (86), Expect = 1.7 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%) Query: 835 FINRFQEITVKEKGTIKLVARVTRNPV-----PSITWYRNNEIISPSETITQNFDGENIE 889 F ++F +E T+ L RV P P + WYRN ++SPS+ + + G+ Sbjct: 319 FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGTLVSPSKWVQTQWSGDRAT 378 Query: 890 LVITNVDSEIDSGDY 904 L ++++ E D G Y Sbjct: 379 LTFSHLNKE-DEGLY 392 Score = 38.3 bits (85), Expect = 2.3 Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 10/124 (8%) Query: 1358 YKLRLENNCGHADVE--MNVTI----LDKPSPPGKPNILEIDSSSINICWDEPENTGNST 1411 +++R N+ G + +VT+ LD P PG+ +S+ + W+E ++ Sbjct: 662 FRVRCSNSAGVGEPSEATDVTVVGDKLDIPKAPGRIIPSRNTDTSVVVTWEESKDA--KE 719 Query: 1412 IIYYVVEYQEIDTTEWISVKN--ITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTE 1469 ++ Y +E + + +W N + ++ L +Y FR AVN +S+ S+ +E Sbjct: 720 LVGYYIESSVVGSGQWEPCNNNPVKGSRFICHGLVNGQNYIFRVRAVNAAGLSEYSQDSE 779 Query: 1470 YYKV 1473 +V Sbjct: 780 AIEV 783 Score = 37.1 bits (82), Expect = 5.3 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 1963 ATVPSPPTAPLEIRMVGSN--IVMTSWGTPEWDGGAPLLGYNI 2003 A + P +PL++ + +N V+ SW P DGG+P+LGY I Sbjct: 416 AEIAGAPASPLDVVCLDANKDYVIISWKQPAVDGGSPILGYFI 458 >UniRef50_UPI0000DB7443 Cluster: PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to Fasciclin 2 CG3665-PB, isoform B isoform 1 - Apis mellifera Length = 741 Score = 89.0 bits (211), Expect = 1e-15 Identities = 147/653 (22%), Positives = 253/653 (38%), Gaps = 69/653 (10%) Query: 1242 FTLISDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIV-DYE--REYR 1298 +T + +L E +YTC A S K ++ I D +Y Sbjct: 68 YTELHQDNSLSLFFNSLQEQQAGKYTCKATYANSIQLQKSVTIDTIVAITWDNAPLNQYP 127 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIY 1358 I G D + +A P P+ +W+ N ++IK H ID+ + L IK V+ +D G+Y Sbjct: 128 IL-GEDFAIQCKVRARPSPSVDWLYNGELIKTNDHY--IIDTYA--LKIKNVQESDDGVY 182 Query: 1359 KLR--------LENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNS 1410 R L+ +V + T+ + P+P N++E +SI C + Sbjct: 183 TCRASVFSTGELKERPIRVEVHIRPTVSEMPNPI---NMIEGKDASIK-CEARGKPPPKF 238 Query: 1411 TIIYYVVEYQEIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEY 1470 T + + +Q + + SV T T I N+ + + ++ A N ++ + T Sbjct: 239 TWVKSLT-HQNLSNVDRFSVDPDTGVLT-ITNVNRDDAGEYQCTATN---LAGTANTNIM 293 Query: 1471 YKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTW--------YRDGKKL 1522 VI + KI +E N T +++ L C G P P+VT+ Y G +L Sbjct: 294 VNVIVKPKI----IE--FLNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQL 347 Query: 1523 KTAKATYENRXXXXXXXXXXXXXXX-------YKCIAFNDHGEVETSCVVGIQQKPVI-T 1574 + EN Y+CIA N G+ + ++ P + Sbjct: 348 DDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFAS 407 Query: 1575 ISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGN-KLENDKEYNITTKEKTSVIRIK 1633 +SN + + ++ + E IP + W G+ K++NDK S++ I Sbjct: 408 MSNTSVWSWDQKPVN--ISCIAESIPNATIRWTMYGDQKIDNDKMITQIGNGPRSILTIV 465 Query: 1634 ELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDD 1693 L + + + Y ASN GT + L+ KP + M EI+ ++ + PP Sbjct: 466 PLDKRYYTTYKCIASNAHGTRQRNIELREATKPGEML-QAKMAEITATTIRFDLVPPSTH 524 Query: 1694 GGLELTKYAIEKHEPDNNRWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSE- 1751 L ++ ++ D WI+ + V++ Y ++ L Y FR A+N VG Sbjct: 525 PEQPLRTINVQ-YKEDGQTWIQARNKTWSVDSYYVLEGLKPQTMYEFRFAARNDVGLGNW 583 Query: 1752 -ALESEPIVIKTALDVPSXXXXXXXXXXIDNESVY-ITWFPSEKNGGSPIIDYKV---EI 1806 AL E +T + P + Y +TW N G PI Y++ +I Sbjct: 584 GALHREMTPGRTVPNEPKIVMSREEYDMSRYSNQYELTWLAPADN-GEPIDMYQIKYCQI 642 Query: 1807 KQEGKKWKX-----XXXXXXXXARI----QKLSINTTYQFRIYARNEIGTSLP 1850 ++ +W+ R+ + L +T Y+ + A N IG S P Sbjct: 643 RRVSGEWETLEDTCRTEDIRTQGRVRHWLRNLYSDTFYKVELKAHNAIGFSKP 695 Score = 77.0 bits (181), Expect = 5e-12 Identities = 82/331 (24%), Positives = 138/331 (41%), Gaps = 37/331 (11%) Query: 635 TFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV 694 T+ P QY G D ++C++ A P P + WL+ GE I +++ + D + Sbjct: 117 TWDNAPLNQYPILGEDFAIQCKVRARPSPSVDWLYNGELIKTNDHYII----DTY----A 168 Query: 695 LKITNVKKFQEGTYTV-VAVNREGE-ASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 LKI NV++ +G YT +V GE PI +++ P V E + + +G+ Sbjct: 169 LKIKNVQESDDGVYTCRASVFSTGELKERPIRVEVHI----RPTVSEMPNPINMIEGKDA 224 Query: 753 ILSAQVVGNPRPTITWCKN--NKPVKALPTKS-DGDTHSITILKPKKVKDEGVYTLKAEN 809 + + G P P TW K+ ++ + + S D DT +TI + D G Y A N Sbjct: 225 SIKCEARGKPPPKFTWVKSLTHQNLSNVDRFSVDPDTGVLTITNVNR-DDAGEYQCTATN 283 Query: 810 SEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITW--- 866 G A T+ ++ V +P + F TV E LV + P P +T+ Sbjct: 284 LAGTANTNIMVNV------IVKPKII--EFLNSTVVEDKEATLVCKAFGRPPPQVTFRKL 335 Query: 867 -----YRNNEIISPSETITQNF--DGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 Y + I +N D E I + + + G Y+C+A N+ G + Sbjct: 336 TAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIG 395 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILEC 950 +T++ +F S + + K V + C Sbjct: 396 HLTVEFPP-SFASMSNTSVWSWDQKPVNISC 425 Score = 71.3 bits (167), Expect = 3e-10 Identities = 102/403 (25%), Positives = 163/403 (40%), Gaps = 61/403 (15%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G +C+V P P + W +IK + +Y D A L I+ V D G +TC Sbjct: 130 GEDFAIQCKVRARPSPSVDWLYNGELIKTND----HYIIDTYA-LKIKNVQESDDGVYTC 184 Query: 584 VAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXXXXXXXXADILEGIPPTFSKKPKAQ 643 A+ F ST EL E P+ + I PT S+ P Sbjct: 185 ---RASVF--STGEL-KERPIR----------------------VEVHIRPTVSEMPNPI 216 Query: 644 YVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKF 703 + EG D ++C P P W+ + + +N+S + VL ITNV + Sbjct: 217 NMIEGKDASIKCEARGKPPPKFTWV----KSLTHQNLSNVDRFSVDPDTGVLTITNVNRD 272 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 G Y A N G A+ I++ + P++IE L S +V E+ ++ + G P Sbjct: 273 DAGEYQCTATNLAGTANTNIMVNVIV----KPKIIEFLNSTVVEDKEATLV-CKAFGRPP 327 Query: 764 PTITWCK---NNKPVKA--------LPTKSDGDTHSI-TILKPKKVK-DEGVYTLKAENS 810 P +T+ K VK + S D+ +I T+ + ++ ++G+Y A+N+ Sbjct: 328 PQVTFRKLTAEKAYVKGPQLDDDRIILENSGDDSETIGTLTISQSLRSNDGLYECIAQNA 387 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 G A +TVE P + + + + V I +A N T Y + Sbjct: 388 GGDARRIGHLTVEFPPSFASMSNTSVWSWDQKPV----NISCIAESIPNATIRWTMY-GD 442 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAG 913 + I + ITQ +G L I +D + YKC+ASN+ G Sbjct: 443 QKIDNDKMITQIGNGPRSILTIVPLDKRYYT-TYKCIASNAHG 484 Score = 49.2 bits (112), Expect = 0.001 Identities = 100/469 (21%), Positives = 179/469 (38%), Gaps = 37/469 (7%) Query: 1023 LQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSV 1081 L + + +D AI + ++ + + V W +GE+IK + Y + L I+N Sbjct: 123 LNQYPILGEDFAI-QCKVRARPSPSVDWLYNGELIKTNDH-YIIDTYA----LKIKNVQE 176 Query: 1082 HDEGEYSCILRDESCTAEVTVVELPPEI-----ITRLQNQ-KVNKGNKATFEIELT-KGD 1134 D+G Y+C S T E+ + E+ ++ + N + +G A+ + E K Sbjct: 177 SDDGVYTCRASVFS-TGELKERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPP 235 Query: 1135 ALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEP 1194 W K + SN + ++D L I + + DDAGEY C N TA + Sbjct: 236 PKFTWVKSLTHQNLSNVDRFSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANTNI-MV 294 Query: 1195 SINFTLRLPEFI--LVPANTDAYLTVEI----PDE------TLDVTWYKKKSVIEDTEKF 1242 ++ ++ EF+ V + +A L + P + T + + K + +D Sbjct: 295 NVIVKPKIIEFLNSTVVEDKEATLVCKAFGRPPPQVTFRKLTAEKAYVKGPQLDDDRIIL 354 Query: 1243 TLISDVKKR--TLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYER-EYR 1298 D + TL I + + Y C+ +A ++ VEFPP Sbjct: 355 ENSGDDSETIGTLTISQSLRSNDGLYECIAQNAGGDARRIGHLTVEFPPSFASMSNTSVW 414 Query: 1299 IKRGSDVTLLVDYQAFPQPNDEW-IVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGI 1357 V + ++ P W + + I K + + LTI ++ Sbjct: 415 SWDQKPVNISCIAESIPNATIRWTMYGDQKIDNDKMITQIGNGPRSILTIVPLDKRYYTT 474 Query: 1358 YKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVV 1417 YK N G + + KP + + EI +++I P + V Sbjct: 475 YKCIASNAHGTRQRNIELREATKPGEMLQAKMAEITATTIRFDLVPPSTHPEQPLRTINV 534 Query: 1418 EYQEIDTTEWISVKNITKTQTS---IQNLKTNSSYRFRAYAVNEVDISD 1463 +Y+E D WI +N T + S ++ LK + Y FR A N+V + + Sbjct: 535 QYKE-DGQTWIQARNKTWSVDSYYVLEGLKPQTMYEFRFAARNDVGLGN 582 Score = 49.2 bits (112), Expect = 0.001 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 1/96 (1%) Query: 499 EKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQM 558 E+P E + P E P + +G +C+ G P P+ TW + S + Sbjct: 196 ERPIRVEVHIRPTVSEMPNPINMIEGKDASIKCEARGKPPPKFTWVKSLTHQNLS-NVDR 254 Query: 559 YYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASS 594 + D + L I V +DAG + C A N AG A++ Sbjct: 255 FSVDPDTGVLTITNVNRDDAGEYQCTATNLAGTANT 290 >UniRef50_UPI00004D30C0 Cluster: Sialoadhesin precursor (Sialic acid-binding Ig-like lectin 1) (Siglec- 1) (CD169 antigen).; n=3; Xenopus tropicalis|Rep: Sialoadhesin precursor (Sialic acid-binding Ig-like lectin 1) (Siglec- 1) (CD169 antigen). - Xenopus tropicalis Length = 1483 Score = 89.0 bits (211), Expect = 1e-15 Identities = 211/1096 (19%), Positives = 415/1096 (37%), Gaps = 137/1096 (12%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP K EG ++ C + + P P + L+K +++ N A +++ Sbjct: 276 PPRIPKFNSFLETQEGKLSIIHCSVDSNP-PSVLTLYKNGQVLATTNSHGAPTQRLNVIS 334 Query: 693 S----VLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQ 748 S L+I V G Y+ VA N G ++ + L ++ VI P S + + Sbjct: 335 SRNSLKLEIREVVMSDAGAYSCVATNAIGNSTACLRLTVEIARL----VISP--SSEIEE 388 Query: 749 GESVILSAQVVGNPRPTI--TWCKNNKPVKALPTKSDGDTHSITILKPK-KVKDEGVYTL 805 G+ V L+ + I TW +N K +K +T T+ P+ +D G Y Sbjct: 389 GKEVTLTCFATRSSEKGIKYTWYRNGKWLK--------ETEEDTVTFPRVSSRDAGSYYC 440 Query: 806 KAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSIT 865 A++S+G + +S T+ A L ++ F + + G I + V +P + Sbjct: 441 LAQSSQG-SSSSPPRTLHVFF---APRDLSVSSFVGSSGRNLGII--LCTVDSDPHSELF 494 Query: 866 WYRNNEIISPSETITQN------FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGA 919 YR +++ S + N +++L I +V E D G Y+C+A+N+ G Sbjct: 495 LYRKETLVASSTMLLHNRRYNISTSPNSLKLEIQDVFLE-DEGAYRCIANNTYGHMMGSL 553 Query: 920 RVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQEG 979 T++ K++ + + T IL + WY N + EG Sbjct: 554 DFTMETAKISVIPTSEVHEAEAVNLTCILNSVSKGNFIYTWYKNS---------VLYSEG 604 Query: 980 RXXXXXXXXXXXXDVGVIKCIVKDQETS------TMLVVKETIPEFIRKLQDFEVKEKDV 1033 D G C + TS + V E ++ D EV + Sbjct: 605 PEPFLMFQRVSSSDSGSYYCRAWNNATSKSSSSCRLHVFYEPRSMQLKSYLDTEVGKSAF 664 Query: 1034 AILEVEINSETADVVWERDGEIIKPKKNKYDFEKRGHIR------KLYIRNTSVHDEGEY 1087 + V+ +++ +D E++ KKN + +R + ++ I++ + DEG+Y Sbjct: 665 ILCTVDSYPPAQMLLYYQD-ELVISKKNLSNVNQRYRVSFSSNALRVDIQDVKLEDEGKY 723 Query: 1088 SCILRDESCTAEVTV---VELPPEIITRLQNQKVNKGNKATFEIELTKGD---ALVRWFK 1141 +C + + T+ V+L ++T + +V + K +LTK + W+K Sbjct: 724 TCTSVNSVGSTNKTIYFKVQLARILVT--PSPEVKENEKVVLTCDLTKTQLEGTMYIWYK 781 Query: 1142 DGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSKCTAILTVEEPSINFTLR 1201 + ++ S+ L D K +D+G Y C+ +S+ + I +++ R Sbjct: 782 NSQRLRESSENTLVFDAVKS---------NDSGYYHCKAHSSQDSTISPSVSLHVSYAPR 832 Query: 1202 LP---EFILVPANTDAYLTVEIPDETL-DVTWYKKKSVIEDT-------EKFTLISDVKK 1250 +P F + + + + L ++ Y+ K ++ T ++ T+ S Sbjct: 833 VPNMTSFWESHSGQVGIIECNVDSDPLSSLSLYRGKLLVGLTASSQTLNQRMTVSSSQNS 892 Query: 1251 RTLIIRKCTEDDQCEYTCVLLDAKSTTKLKVEVVEFPPKIVDYEREYRIKRGSDV--TLL 1308 L+IR +D+ EY C ++ + + +I+ +++ G V T L Sbjct: 893 LKLVIRDVVLEDEGEYVCTASNSIGHSTSAINFTAQTSRIL-ISPSSQVQEGMTVNLTCL 951 Query: 1309 VDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLENN-CG 1367 V A + W N K +H + S S +L +V + D G+Y + ++ Sbjct: 952 VASNAPGEVEYSWFQNGK-----EHPRGS----SKTLLFGRVSSEDGGLYYCTVRSDKVT 1002 Query: 1368 HADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQEIDTTEW 1427 A +N+ + P + +E + + I ++ S ++ + E+Q + Sbjct: 1003 KASPTINLNVTYAPRNAYIKSFVETQNGEVAIIQCGVDSNPPSQLL-LLKEHQVV----- 1056 Query: 1428 ISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYY--KVIKETKIQSPTVE 1485 + + + + + N + + D+ E T + K + TK S + Sbjct: 1057 -----ASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPTDEGTYIFTAKNVHGTKSVSSHLA 1111 Query: 1486 KPLKNITTEPN------EDIELTCIFGGVPQP--KVTWYRDGKKLKTAKATYENRXXXXX 1537 + I P+ + LTC PQP TWY++G+ + Sbjct: 1112 VEVARILVNPSPKLNEGQSATLTCNVLSTPQPVTSYTWYKNGRWFQEGFP-----GSLAF 1166 Query: 1538 XXXXXXXXXXYKCIAFNDHGE-VETSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVI 1596 Y C +G + +Q P + ++ K D+ ++ + Sbjct: 1167 EKVLSADAGTYACTGHTANGTWPSLPITLYVQYAPKNLLVTSFLEPHGK--DQGIILCKL 1224 Query: 1597 EGIPPPEVIWYKNGNKL------ENDKEYNITTKEKTSVIR--IKELKRSHSSKYTIEAS 1648 + +PP + ++ G L + D+ + + +R I+++ S +Y A+ Sbjct: 1225 DSVPPSVITLHREGTVLASTMPAQPDQGQKFWSFSSHNYLRLEIRDVTAEDSGRYVCTAN 1284 Query: 1649 NTAG--TSSVEVTLKV 1662 NT G TSSV T+ V Sbjct: 1285 NTIGSTTSSVLFTINV 1300 Score = 82.6 bits (195), Expect = 1e-13 Identities = 192/979 (19%), Positives = 369/979 (37%), Gaps = 129/979 (13%) Query: 746 VRQGESVILSAQVVGNPRPTI--TWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVY 803 VR+GE+V L+ V G I +W KN+ +K DG T S+ IL D G Y Sbjct: 201 VREGEAVTLTCDVPGADPDQIHYSWYKNSLWIK------DGATRSL-ILYEAAASDAGYY 253 Query: 804 TLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLV-ARVTRNPVP 862 + K +N +G + VI PP I +F ++G + ++ V NP Sbjct: 254 SCKVQNDKGSDSSPPVIL------HVLYPPR-IPKFNSFLETQEGKLSIIHCSVDSNPPS 306 Query: 863 SITWYRNNEIIS-------PSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKS 915 +T Y+N ++++ P++ + +++L I V D+G Y CVA+N+ G S Sbjct: 307 VLTLYKNGQVLATTNSHGAPTQRLNVISSRNSLKLEIREVVMS-DAGAYSCVATNAIGNS 365 Query: 916 SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSHT----VSTKWYHNKKEISGMD 971 + R+T+++ ++ + S E EEGK V L C + + + WY N K Sbjct: 366 TACLRLTVEIARLV----ISPSSEIEEGKEVTLTCFATRSSEKGIKYTWYRNGK------ 415 Query: 972 HREIIQEGRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETIPEFIRKLQDFEVKE- 1030 ++E D G C+ + + S+ + T+ F +D V Sbjct: 416 ---WLKETEEDTVTFPRVSSRDAGSYYCLAQSSQGSSSSPPR-TLHVFFAP-RDLSVSSF 470 Query: 1031 -----KDVAILEVEINSET-ADVVWERDGEIIKPK-----KNKYDFEKRGHIRKLYIRNT 1079 +++ I+ ++S+ +++ R ++ +Y+ + KL I++ Sbjct: 471 VGSSGRNLGIILCTVDSDPHSELFLYRKETLVASSTMLLHNRRYNISTSPNSLKLEIQDV 530 Query: 1080 SVHDEGEYSCILRDE----SCTAEVTVVELPPEIITRLQNQKVNKGNKATFEIELTKGDA 1135 + DEG Y CI + + + T+ +I + + N ++KG+ Sbjct: 531 FLEDEGAYRCIANNTYGHMMGSLDFTMETAKISVIPTSEVHEAEAVNLTCILNSVSKGNF 590 Query: 1136 LVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGN-------SKCTAI 1188 + W+K + + +S +G + L D+G Y C N S C Sbjct: 591 IYTWYK--NSVLYS-------EGPEPFLMFQRVSSSDSGSYYCRAWNNATSKSSSSCRLH 641 Query: 1189 LTVEEPSINFTLRLPEFI----LVPANTDAYLTVEIPDETLDVTWYKKKSVIEDTEKFTL 1244 + E S+ L + + D+Y ++ D KK++ +++ + Sbjct: 642 VFYEPRSMQLKSYLDTEVGKSAFILCTVDSYPPAQMLLYYQDELVISKKNLSNVNQRYRV 701 Query: 1245 ISDVKKRTLIIRKCTEDDQCEYTCVLLDA-KSTTKLKVEVVEFPPKIVDYEREYRIKRGS 1303 + I+ +D+ +YTC +++ ST K V+ +V E +K Sbjct: 702 SFSSNALRVDIQDVKLEDEGKYTCTSVNSVGSTNKTIYFKVQLARILVTPSPE--VKENE 759 Query: 1304 DVTLLVDYQAFPQPNDE--WIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLR 1361 V L D W NS+ ++ +S +L V++ D+G Y + Sbjct: 760 KVVLTCDLTKTQLEGTMYIWYKNSQRLR---------ESSENTLVFDAVKSNDSGYYHCK 810 Query: 1362 LENNCGHA-DVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYVVEYQ 1420 ++ +++ + P P + E S + I ++ S++ Y + Sbjct: 811 AHSSQDSTISPSVSLHVSYAPRVPNMTSFWESHSGQVGIIECNVDSDPLSSLSLYRGK-- 868 Query: 1421 EIDTTEWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASE--TTEYYKVIKETK 1478 + V +QT Q + +SS + +V + D E T + T Sbjct: 869 -------LLVGLTASSQTLNQRMTVSSSQNSLKLVIRDVVLEDEGEYVCTASNSIGHSTS 921 Query: 1479 IQSPTVE--KPLKNITTEPNE--DIELTC-IFGGVP-QPKVTWYRDGKKLKTAKATYENR 1532 + T + + L + +++ E + LTC + P + + +W+++GK+ + Sbjct: 922 AINFTAQTSRILISPSSQVQEGMTVNLTCLVASNAPGEVEYSWFQNGKEHPRGSS----- 976 Query: 1533 XXXXXXXXXXXXXXXYKCIAFNDHGEVETSCVVGIQQKPVITISNEDIKQ--KHKVGDEW 1590 Y C +D T I N IK + + G+ Sbjct: 977 KTLLFGRVSSEDGGLYYCTVRSDK---VTKASPTINLNVTYAPRNAYIKSFVETQNGEVA 1033 Query: 1591 LVTAVIEGIPPPEVIWYKN-------GNKLENDKEYNITTKEKTSVIRIKELKRSHSSKY 1643 ++ ++ PP +++ K G+ + + +N T + IK+L + Y Sbjct: 1034 IIQCGVDSNPPSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPTDEGTY 1093 Query: 1644 TIEASNTAGTSSVEVTLKV 1662 A N GT SV L V Sbjct: 1094 IFTAKNVHGTKSVSSHLAV 1112 Score = 62.1 bits (144), Expect = 2e-07 Identities = 103/483 (21%), Positives = 189/483 (39%), Gaps = 62/483 (12%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSV----LKITNVKKF 703 G +++C + + P P L K ++V S + Y S L+I ++ Sbjct: 1030 GEVAIIQCGVDSNP-PSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLMPT 1088 Query: 704 QEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPR 763 EGTY A N G S+ L ++ ++ P S + +G+S L+ V+ P+ Sbjct: 1089 DEGTYIFTAKNVHGTKSVSSHLAVEVARI----LVNP--SPKLNEGQSATLTCNVLSTPQ 1142 Query: 764 P--TITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVIT 821 P + TW KN + + +G S+ K D G Y + G + + Sbjct: 1143 PVTSYTWYKNGRWFQ------EGFPGSLAFEKVLSA-DAGTYACTGHTANGTWPSLPITL 1195 Query: 822 VEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQ 881 + +N L + F E K++G I + ++ P IT +R +++ + Sbjct: 1196 YVQYAPKN----LLVTSFLEPHGKDQGII--LCKLDSVPPSVITLHREGTVLASTMPAQP 1249 Query: 882 N-------FDGEN-IELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTIDVEKVTFVKH 933 + F N + L I +V +E DSG Y C A+N+ G ++ TI+V ++ Sbjct: 1250 DQGQKFWSFSSHNYLRLEIRDVTAE-DSGRYVCTANNTIGSTTSSVLFTINVARIL---- 1304 Query: 934 LQKSYETEEGKTVILECQTSHT----VSTKWYHNKKEISGMDHREIIQEGRXXXXXXXXX 989 + S E +E + V+L C + T WY N + ++E Sbjct: 1305 VTPSPEVKENEKVVLTCDLTKTQLEGTMYIWYKNSQR---------LRESSENTLVFDAV 1355 Query: 990 XXXDVGVIKCIVKDQETSTM---LVVKETIPEFIRKLQDF-EVKEKDVAILEVEINSE-T 1044 D G C + ST+ + + + P L F E + K ++ + S+ Sbjct: 1356 KSNDSGYYHCKAHSSQDSTISPSVSLHVSYPPRNLSLSSFLEAQGKRQGVISCRVESDPP 1415 Query: 1045 ADVVWERDGEI----IKPKKNKYDFEKRGH-IRKLYIRNTSVHDEGEYSCILRDESCTAE 1099 + +V + G++ + NK H +L + + D+GEY+C + A+ Sbjct: 1416 SQLVLYKGGQVAASFVPQSTNKRVRLSSSHNALRLEMEEVAPEDQGEYTCQATNSLGAAQ 1475 Query: 1100 VTV 1102 +V Sbjct: 1476 TSV 1478 Score = 46.8 bits (106), Expect = 0.007 Identities = 75/346 (21%), Positives = 128/346 (36%), Gaps = 58/346 (16%) Query: 861 VPSITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGAR 920 V TWYRNN++ S + +F IT D GD++C N G + Sbjct: 137 VSGYTWYRNNKVFSREPIV--SFPS------ITRQ----DFGDFRCEVQNPEGTGTSEVS 184 Query: 921 VTIDVEKVTFVKHLQKSYETEEGKTVILECQT----SHTVSTKWYHNKKEISGMDHREII 976 I T V S E EG+ V L C + WY N I Sbjct: 185 RLIVFSANTLV---SPSSEVREGEAVTLTCDVPGADPDQIHYSWYKNSL---------WI 232 Query: 977 QEGRXXXXXXXXXXXXDVGVIKCIV---KDQETSTMLVVKETIPEFIRKLQDF-EVKEKD 1032 ++G D G C V K ++S +++ P I K F E +E Sbjct: 233 KDGATRSLILYEAAASDAGYYSCKVQNDKGSDSSPPVILHVLYPPRIPKFNSFLETQEGK 292 Query: 1033 VAILEVEINSETADVV-WERDGEII-------KPKKNKYDFEKRGHIRKLYIRNTSVHDE 1084 ++I+ ++S V+ ++G+++ P + R + KL IR + D Sbjct: 293 LSIIHCSVDSNPPSVLTLYKNGQVLATTNSHGAPTQRLNVISSRNSL-KLEIREVVMSDA 351 Query: 1085 GEYSCILRD---ESCTAEVTVVELPPEIITRLQNQKVNKGNKAT---FEIELTKGDALVR 1138 G YSC+ + S VE+ +I+ + ++ +G + T F ++ Sbjct: 352 GAYSCVATNAIGNSTACLRLTVEIARLVIS--PSSEIEEGKEVTLTCFATRSSEKGIKYT 409 Query: 1139 WFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVGNSK 1184 W+++G ++ + +T + DAG Y C +S+ Sbjct: 410 WYRNGKWLKETEEDTVTFPRVSSR---------DAGSYYCLAQSSQ 446 Score = 39.1 bits (87), Expect = 1.3 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 8/88 (9%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIK-------PSQDFQMYYDDDNVATLVIREV 573 T +G C V+ P +T ++ ++ P+Q + N L IREV Sbjct: 288 TQEGKLSIIHCSVDSNPPSVLTLYKNGQVLATTNSHGAPTQRLNVI-SSRNSLKLEIREV 346 Query: 574 FPEDAGTFTCVAKNAAGFASSTTELIVE 601 DAG ++CVA NA G +++ L VE Sbjct: 347 VMSDAGAYSCVATNAIGNSTACLRLTVE 374 Score = 39.1 bits (87), Expect = 1.3 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 6/87 (6%) Query: 521 TPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY------YDDDNVATLVIREVF 574 T +G +C V+ P Q+ ++ ++ D ++ Y N L I+++ Sbjct: 1027 TQNGEVAIIQCGVDSNPPSQLLLLKEHQVVASLGDSGLHHQRFNPYFSPNTLRLEIKDLM 1086 Query: 575 PEDAGTFTCVAKNAAGFASSTTELIVE 601 P D GT+ AKN G S ++ L VE Sbjct: 1087 PTDEGTYIFTAKNVHGTKSVSSHLAVE 1113 >UniRef50_Q4SAP3 Cluster: Chromosome undetermined SCAF14681, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14681, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 862 Score = 89.0 bits (211), Expect = 1e-15 Identities = 85/332 (25%), Positives = 137/332 (41%), Gaps = 22/332 (6%) Query: 1592 VTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRIKELKRSHSSKYTIEASNTA 1651 +T V G P P V W L + + I +V+ + ++++S + YT A +T Sbjct: 339 ITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGR----NVLELTDVRQS--ANYTCVAMSTL 392 Query: 1652 GTSSVEVTLKVYDKPSKPEGPVIMREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNN 1711 G + V P P PV+ E + S+T+ W D G E Y I +H+ + Sbjct: 393 GVIEAMAQITVKALPKAPGTPVVT-ERTATSITLTW----DSGNPEPVSYYIIQHKSKYS 447 Query: 1712 RWIKVADVDRDVET-YCIQKLNENCEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXX 1770 + ++D T Y + L+ +Y FRV+A N +G SE I KTA PS Sbjct: 448 DDL-YKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIG--RGPPSEIIEAKTAEQAPSTA 504 Query: 1771 XXXXXXXXIDNESVYITWFPSEKNGGSPI---IDYKVEIKQEGKKWKXXXXXXXXXARIQ 1827 + + + I W E+ G + + Y ++ Q W+ IQ Sbjct: 505 PRQVRGHMMSSTTAVIHWDEPEEANGQIMGYRVYYTMDSSQHVNLWEKQIVRGSKFVTIQ 564 Query: 1828 KLSINTTYQFRIYARNEIGTSLPYTSDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWT 1887 L N TY ++ A +G P + D +I I KT P SQP +F + S+ L W Sbjct: 565 GLIPNKTYYIKVLAYTSVGDG-PLSPDLQI-ITKTGVP-SQPTDFKAEAKSETSILLSWI 621 Query: 1888 EPESNG-GSPITNYIIEFKTVKGKSWTKIVTV 1918 P G + IT Y + ++ +I+ + Sbjct: 622 APAQTGQENQITGYELVYRKSDDTEEVRILAI 653 Score = 66.5 bits (155), Expect = 8e-09 Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 15/189 (7%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALP---TKSDGDTHSIT 790 PP+ + QG Q G+PRP I W K K V + + D + S+ Sbjct: 67 PPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVSSQRFEVIEFDDGSGSVL 126 Query: 791 ILKPKKV-KDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLF--INRFQEITVKEK 847 ++P + +DE +Y A NS G + +TV E+ PP F I+ ++ V E+ Sbjct: 127 RIQPLRTPRDEAIYECVASNSVGETSATTRLTV---LREDQLPPGFPTIDMGPQLKVVER 183 Query: 848 G-TIKLVARVTRNPVPSITWYRNNEIISPSETITQNFDGENIELVITNVDS--EIDSGDY 904 T ++ + NP P I+W+++ P T T N + + ++ E D G Y Sbjct: 184 TRTATMLCAASGNPDPDISWFKD---FLPVNTTTNNGRIKQLRSGALQIEQSEESDQGKY 240 Query: 905 KCVASNSAG 913 +CVA+N+ G Sbjct: 241 ECVATNNDG 249 Score = 59.3 bits (137), Expect = 1e-06 Identities = 63/247 (25%), Positives = 99/247 (40%), Gaps = 32/247 (12%) Query: 502 TSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMY-Y 560 T + P F+ + G F CQ G PRP+I W ++ + SQ F++ + Sbjct: 60 TPVDSGAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVS-SQRFEVIEF 118 Query: 561 DDDNVATLVIREV-FPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXXXXX 619 DD + + L I+ + P D + CVA N+ G S+TT L V Sbjct: 119 DDGSGSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTV------------------- 159 Query: 620 XXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDEN 679 D L PT P+ + V+ + C P+PDI+W FK + +P N Sbjct: 160 ----LREDQLPPGFPTIDMGPQLKVVERTRTATMLCAASGNPDPDISW-FK--DFLP-VN 211 Query: 680 ISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREG-EASLPIVLKIKTGEKEPPQVI 738 + + L+I ++ +G Y VA N +G S P L ++ G K P Sbjct: 212 TTTNNGRIKQLRSGALQIEQSEESDQGKYECVATNNDGTRYSAPANLYVR-GRKLAPAAF 270 Query: 739 EPLKSMI 745 L + + Sbjct: 271 ARLSNTL 277 Score = 57.2 bits (132), Expect = 5e-06 Identities = 55/191 (28%), Positives = 83/191 (43%), Gaps = 15/191 (7%) Query: 631 GIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 G PP F + P Q +G C+ P P I W KG++ V + V IE D Sbjct: 65 GAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKK-VSSQRFEV-IEFD-DG 121 Query: 691 YCSVLKITNVK-KFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQV----IEPLKSMI 745 SVL+I ++ E Y VA N GE S L + ++ PP + P ++ Sbjct: 122 SGSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTVLREDQLPPGFPTIDMGPQLKVV 181 Query: 746 VRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITI----LKPKKVKDEG 801 R + +L A GNP P I+W K+ PV T ++G + ++ + D+G Sbjct: 182 ERTRTATMLCA-ASGNPDPDISWFKDFLPVNT--TTNNGRIKQLRSGALQIEQSEESDQG 238 Query: 802 VYTLKAENSEG 812 Y A N++G Sbjct: 239 KYECVATNNDG 249 Score = 51.6 bits (118), Expect = 2e-04 Identities = 38/185 (20%), Positives = 75/185 (40%), Gaps = 12/185 (6%) Query: 1287 PPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLT 1346 PP+ + I G V + P P +W++ ++ + P D Sbjct: 319 PPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT------PEDDMPIGRNV 372 Query: 1347 IKKVENTDAGIYKLRLENNCGHADVEMNVTILDKPSPPGKPNILEIDSSSINICWDEPEN 1406 ++ + + Y + G + +T+ P PG P + E ++SI + WD Sbjct: 373 LELTDVRQSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTWD---- 428 Query: 1407 TGN-STIIYYVVEYQEIDTTE-WISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDA 1464 +GN + YY+++++ + + + + + T+ S+ L S Y FR A+N + Sbjct: 429 SGNPEPVSYYIIQHKSKYSDDLYKEIDGVATTRYSVGGLSPYSDYEFRVVAINNIGRGPP 488 Query: 1465 SETTE 1469 SE E Sbjct: 489 SEIIE 493 Score = 51.2 bits (117), Expect = 3e-04 Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 1/97 (1%) Query: 828 ENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQNFD-GE 886 ++ PP F+ + T + G V + T +P P I W + + +S FD G Sbjct: 63 DSGAPPKFLRTPNDQTGVQGGVASFVCQATGDPRPKIVWNKKGKKVSSQRFEVIEFDDGS 122 Query: 887 NIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 L I + + D Y+CVASNS G++S R+T+ Sbjct: 123 GSVLRIQPLRTPRDEAIYECVASNSVGETSATTRLTV 159 Score = 46.8 bits (106), Expect = 0.007 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 20/135 (14%) Query: 632 IPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMY 691 +PP FS P + G + + C V P P + W+ E++ P E DM + Sbjct: 318 VPPRFSIPPTDNEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP--------EDDMPIG 369 Query: 692 CSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEP--PQVIEPLKSMIVRQG 749 +VL++T+V+ Q YT VA++ G + +K K P P V E + I Sbjct: 370 RNVLELTDVR--QSANYTCVAMSTLGVIEAMAQITVKALPKAPGTPVVTERTATSITLTW 427 Query: 750 ESVILSAQVVGNPRP 764 +S GNP P Sbjct: 428 DS--------GNPEP 434 Score = 37.9 bits (84), Expect = 3.0 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 1598 GIPPPEVIWYKNGNKLENDKEYNITTKEKT-SVIRIKELKRSHSSK-YTIEASNTAGTSS 1655 G P P+++W K G K+ + + I + + SV+RI+ L+ Y ASN+ G +S Sbjct: 93 GDPRPKIVWNKKGKKVSSQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNSVGETS 152 Query: 1656 VEVTLKVYDKPSKPEG 1671 L V + P G Sbjct: 153 ATTRLTVLREDQLPPG 168 >UniRef50_Q9UBF9 Cluster: Myotilin; n=18; Tetrapoda|Rep: Myotilin - Homo sapiens (Human) Length = 498 Score = 88.6 bits (210), Expect = 2e-15 Identities = 55/206 (26%), Positives = 94/206 (45%), Gaps = 8/206 (3%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 PP F + P+ +DEG ++ ++ +P PD++W G + D+ + I S+ ++ Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD-LHKMIVSEKGLHS 307 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGE-KEPPQVIEPLKSMIVRQGES 751 + ++ V+ G Y VA NR GEA+ + L + E K P I +S V +G+S Sbjct: 308 LIFEV--VRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365 Query: 752 VILSAQVVGNPRPTITWCKNNKPVK----ALPTKSDGDTHSITILKPKKVKDEGVYTLKA 807 V L Q+ P P + W +NN+ V+ + D ++K KD G YT+ A Sbjct: 366 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 425 Query: 808 ENSEGIAETSAVITVEEPTEENAEPP 833 N G+ + + V + P Sbjct: 426 VNEAGVTTCNTRLDVTARPNQTLPAP 451 Score = 77.0 bits (181), Expect = 5e-12 Identities = 65/251 (25%), Positives = 108/251 (43%), Gaps = 30/251 (11%) Query: 497 VFEKPTSEEQSMAPIFVEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPSQDF 556 V ++ +E+ P F++ +G + + +V G P P ++W+ ++ Sbjct: 237 VNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLH 296 Query: 557 QMYYDDDNVATLVIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTVXXX 616 +M + + +L+ V DAG + CVAKN AG A+ T +L V A +H Sbjct: 297 KMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA--KEHKR------- 347 Query: 617 XXXXXXXXXADILEGIPPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVP 676 P F KP+++ V EG + LEC++ AIP P + W + E+V Sbjct: 348 ----------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK-RNNEMVQ 390 Query: 677 DENISVAIESDMHMYCSVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQ 736 +++ D ++L I +V K G YTV AVN G + L + P Q Sbjct: 391 FNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA---RPNQ 446 Query: 737 VIEPLKSMIVR 747 + K + VR Sbjct: 447 TLPAPKQLRVR 457 Score = 74.9 bits (176), Expect = 2e-11 Identities = 52/196 (26%), Positives = 99/196 (50%), Gaps = 10/196 (5%) Query: 734 PPQVIEPLKSMIVRQGESVILSAQVVGNPRPTITWCKNNKPVKALPTK----SDGDTHSI 789 PP+ I+ ++M + +G + +V G P P ++W N + V++ S+ HS+ Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308 Query: 790 TILKPKKVKDEGVYTLKAENSEGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGT 849 I + + D G Y A+N G E + + ++ +E+ P+FI + Q V E + Sbjct: 309 -IFEVVRASDAGAYACVAKNRAG--EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 365 Query: 850 IKLVARVTRNPVPSITWYRNNEIIS-PSETITQNFDGE-NIELVITNVDSEIDSGDYKCV 907 +KL +++ P P + W RNNE++ ++ I+ D + L+I +V+ + D+G Y Sbjct: 366 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKK-DAGWYTVS 424 Query: 908 ASNSAGKSSHGARVTI 923 A N AG ++ R+ + Sbjct: 425 AVNEAGVTTCNTRLDV 440 Score = 57.6 bits (133), Expect = 4e-06 Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%) Query: 823 EEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNNEIISPSETITQN 882 ++ +E PP FI + +++ E ++ +V+ P P ++WY N + + Sbjct: 240 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 299 Query: 883 FDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI---DVEKVTFVKHLQKSYE 939 + + +I V D+G Y CVA N AG+++ ++ + + ++ + +S + Sbjct: 300 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK 359 Query: 940 TEEGKTVILECQTSHTVSTK--WYHNKKEI 967 EG +V LECQ S K W N + + Sbjct: 360 VLEGDSVKLECQISAIPPPKLFWKRNNEMV 389 Score = 54.0 bits (124), Expect = 4e-05 Identities = 40/203 (19%), Positives = 83/203 (40%), Gaps = 10/203 (4%) Query: 1476 ETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGKKLKTAK-----ATYE 1530 + K P + +N++ + + G+P P V+WY +G+ +++ + + Sbjct: 244 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 303 Query: 1531 NRXXXXXXXXXXXXXXXYKCIAFNDHGEVETSC---VVGIQQKPVITISNEDIKQKHKVG 1587 Y C+A N GE + V+ + K + +K G Sbjct: 304 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEG 363 Query: 1588 DEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTS--VIRIKELKRSHSSKYTI 1645 D + I IPPP++ W +N ++ + + ++ T + IK++ + + YT+ Sbjct: 364 DSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 423 Query: 1646 EASNTAGTSSVEVTLKVYDKPSK 1668 A N AG ++ L V +P++ Sbjct: 424 SAVNEAGVTTCNTRLDVTARPNQ 446 Score = 39.1 bits (87), Expect = 1.3 Identities = 22/96 (22%), Positives = 38/96 (39%), Gaps = 1/96 (1%) Query: 1286 FPPKIVDYEREYRIKRGSDVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSA-S 1344 +PP+ + I G + P P+ W +N + ++ K + K S Sbjct: 248 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 307 Query: 1345 LTIKKVENTDAGIYKLRLENNCGHADVEMNVTILDK 1380 L + V +DAG Y +N G A + + +L K Sbjct: 308 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 343 Score = 38.3 bits (85), Expect = 2.3 Identities = 42/209 (20%), Positives = 90/209 (43%), Gaps = 14/209 (6%) Query: 1106 PPEIITRLQNQKVNKGNKATFEIELTKGDAL-VRWFKDGSEIQFSNHIQLTIDGKKQKLK 1164 PP I +N +++G + +++ A V W+ +G +Q + ++ + K Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308 Query: 1165 IYDC-DLDDAGEYSCEVGNSKCTAILTVE-EPSINFTLRLPEFILVPANTDAY----LTV 1218 I++ DAG Y+C N A TV+ + R P FI P + + + Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368 Query: 1219 EIPDETL---DVTWYKKKSVIE-DTEKFTLISDVKKR-TLIIRKCTEDDQCEYTCVLLD- 1272 E + + W + +++ +T++ +L D R TL+I+ + D YT ++ Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 428 Query: 1273 -AKSTTKLKVEVVEFPPKIVDYEREYRIK 1300 +T +++V P + + ++ R++ Sbjct: 429 AGVTTCNTRLDVTARPNQTLPAPKQLRVR 457 >UniRef50_Q5XNV8 Cluster: Neogenin/DCC long isoform; n=5; Vertebrata|Rep: Neogenin/DCC long isoform - Petromyzon marinus (Sea lamprey) Length = 1415 Score = 88.2 bits (209), Expect = 2e-15 Identities = 116/521 (22%), Positives = 203/521 (38%), Gaps = 40/521 (7%) Query: 1461 ISDASETTEYYKVIKETKIQSPTVEKPLKNITTEPNEDIELTCIFGGVPQPKVTWYRDGK 1520 I +ET Y K T ++ P + +N ++DI L C G P+P ++W+++G Sbjct: 312 IKAQNETQRLYA--KLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGD 369 Query: 1521 KLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFN--DHGEVETSCVVGIQQKPVITISNE 1578 + Y+C+A + D + VV P I S+ Sbjct: 370 LIIPDDFIQIVDGSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSP 429 Query: 1579 D------IKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYNITTKEKTSVIRI 1632 + + W A G ++Y + + + E V+ Sbjct: 430 PRGMTAVLVSTRFIRLSWRAPAESRGSVLHYSVYYVRVGSVRERRVDTLQVSELQLVVG- 488 Query: 1633 KELKRSHSSKYTIEASNTAGTSSVEVTLKVYDKPS-KPEGPVI---MREISRESVTIEWK 1688 EL+ + + A N AG L++ +P + GPV+ + IS SV+++W Sbjct: 489 -ELRPETGYSFQVVAVNQAGPGERSAPLRITTQPEVQVPGPVLNLHVVAISTTSVSLQWD 547 Query: 1689 PPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNENCEYMFRVIAQNPVG 1748 PP + + Y + + D + D D D ++ + L + Y FRV+A N G Sbjct: 548 PPANVFS-PIMHYKLYYMQLDGEATTE-HDQDTDGPSFTKEGLRKFTRYSFRVVAYNKHG 605 Query: 1749 FSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPS--EKNGGSPIIDYKVEI 1806 + SE +++T DVPS ++++SV + W P E + G I YK Sbjct: 606 --PGVSSEDTIVRTYSDVPSGSPQELILEVVNSQSVLVRWKPPLLETHNGD-ITGYK--- 659 Query: 1807 KQEGKKWKXXXXXXXXXARIQKLSI----NTTYQFRIYARNEIGTSLPYTS-DDKITIGK 1861 + EGK + A + L++ + Y FR+ A N GT P++ T Sbjct: 660 RHEGKAGRRAEAEIEETAHLSYLAVGLDRGSEYSFRVAAVNSNGTG-PFSDWLSSETFQA 718 Query: 1862 TLTP---PSQPRNFVVSESTSRSVTLKWTEPESNGGSPITNYIIEFKTVKGKSWTKIVTV 1918 L P QP + V + S+ + WT P +N + Y + + G K + V Sbjct: 719 DLDESRVPDQPSSLHVRPFPT-SIVVSWT-PPANPQIMVRGYALGYGI--GSPHGKSLRV 774 Query: 1919 GGSVHEHCIENIKEKDEIIFRISAENTVGVSLPT-ESQSVR 1958 + I+N++ + + + A N +G +P ES + R Sbjct: 775 DSKQRYYTIDNLEPSSQYVISLKAFNHMGEGIPLYESATTR 815 Score = 85.8 bits (203), Expect = 1e-14 Identities = 123/570 (21%), Positives = 217/570 (38%), Gaps = 39/570 (6%) Query: 1501 LTCIFGGVPQPKVTWYRDGKKLKTAKATYENRXXXXXXXXXXXXXXXYKCIAFNDHGEVE 1560 L C+ G P P V W R + + + + + Y CI + Sbjct: 261 LECVVAGFPAPSVHWTRGTESVLSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQNETQR 320 Query: 1561 TSCVVGIQQKPVITISNEDIKQKHKVGDEWLVTAVIEGIPPPEVIWYKNGNKLENDKEYN 1620 + + + P I E+ + V D+ ++ EG P P + W++NG+ + D Sbjct: 321 LYAKLTVLEPPRILHGPEN--RNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQ 378 Query: 1621 ITTKEKTSVIRIKELKRSHSSKYTIEASNTAGTSSVEVTLKVYDK------PSKPEGPVI 1674 I + I + S Y A + L V + S P + Sbjct: 379 IV----DGSLHILGVMASDEGVYQCMAESEVDGMQAAAQLVVINHAVPGILASSPPRGMT 434 Query: 1675 MREISRESVTIEWKPPLDDGGLELTKYAIEKHEPDNNRWIKVADVDRDVETYCIQKLNEN 1734 +S + + W+ P + G + Y++ + R +V + + +L Sbjct: 435 AVLVSTRFIRLSWRAPAESRG-SVLHYSVYYVRVGSVRERRVDTLQVSELQLVVGELRPE 493 Query: 1735 CEYMFRVIAQNPVGFSEALESEPIVIKTALDVPSXXXXXXXXXXIDNESVYITWFPSEKN 1794 Y F+V+A N G E I + + VP I SV + W P N Sbjct: 494 TGYSFQVVAVNQAGPGERSAPLRITTQPEVQVPG-PVLNLHVVAISTTSVSLQWDP-PAN 551 Query: 1795 GGSPIIDYKVEIKQEGKKWKXXXXXXXXXARIQKLSIN--TTYQFRIYARNEIGTSLPYT 1852 SPI+ YK+ Q + K + T Y FR+ A N+ G + + Sbjct: 552 VFSPIMHYKLYYMQLDGEATTEHDQDTDGPSFTKEGLRKFTRYSFRVVAYNKHGPGV--S 609 Query: 1853 SDDKITIGKTLTPPSQPRNFVVSESTSRSVTLKWTEP--ESNGGSPITNYIIEFKTVKGK 1910 S+D I + P P+ ++ S+SV ++W P E++ G IT Y K +GK Sbjct: 610 SEDTIVRTYSDVPSGSPQELILEVVNSQSVLVRWKPPLLETHNGD-ITGY----KRHEGK 664 Query: 1911 SWTKI-VTVGGSVH-EHCIENIKEKDEIIFRISAENTVGVS-----LPTESQSVRLEKHA 1963 + + + + H + + E FR++A N+ G L +E+ L++ + Sbjct: 665 AGRRAEAEIEETAHLSYLAVGLDRGSEYSFRVAAVNSNGTGPFSDWLSSETFQADLDE-S 723 Query: 1964 TVPSPPTAPLEIRMVGSNIVMTSWGTPEWDGGAPLLGYNIAIRDVTKTMWMEVGKVDVNT 2023 VP P++ L +R ++IV+ SW TP + + GY + + + +VD Sbjct: 724 RVPDQPSS-LHVRPFPTSIVV-SW-TPPANPQIMVRGYALGY-GIGSPHGKSL-RVDSKQ 778 Query: 2024 LKFNIRDLSENHTYMIRIYARNEIGLSEPL 2053 + I +L + Y+I + A N +G PL Sbjct: 779 RYYTIDNLEPSSQYVISLKAFNHMGEGIPL 808 Score = 66.9 bits (156), Expect = 6e-09 Identities = 79/368 (21%), Positives = 150/368 (40%), Gaps = 39/368 (10%) Query: 1137 VRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGEYSCEVG------NSKCTAILT 1190 VRWFK+G I + + + G L + + D G+Y C++ ++ T + Sbjct: 176 VRWFKEGRSITEDSQVMVLSSGD---LLLQNASKADGGKYFCQLVFGGRTFTNQGTNLSV 232 Query: 1191 VEEPSIN---FTLRLPEFILVPANTDAYLTVEIPD-ETLDVTWYK-KKSVIEDTEKFTLI 1245 + E N LR P + V A L + V W + +SV+ +E+F+++ Sbjct: 233 LPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVL--SERFSVV 290 Query: 1246 SDVKKRTLIIRKCTEDDQCEYTCVLLDAKSTTKL--KVEVVEFPPKIVDYEREYRIKRGS 1303 + L I +DD +YTC++ T +L K+ V+E PP+I+ Sbjct: 291 AG---GILRIDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLE-PPRILHGPENRNASVSD 346 Query: 1304 DVTLLVDYQAFPQPNDEWIVNSKIIKKCKHTKPSIDSKSASLTIKKVENTDAGIYKLRLE 1363 D+ L + P+P W N +I I SL I V +D G+Y+ E Sbjct: 347 DIILECQAEGRPRPVISWFQNGDLI----IPDDFIQIVDGSLHILGVMASDEGVYQCMAE 402 Query: 1364 NNCGHADVEMNVTILD-------KPSPPGKPNILEIDSSSINICWDEPENTGNSTIIYYV 1416 + + +++ SPP + + + I + W P + S +++Y Sbjct: 403 SEVDGMQAAAQLVVINHAVPGILASSPPRGMTAVLVSTRFIRLSWRAPAESRGS-VLHYS 461 Query: 1417 VEYQEIDTT--EWISVKNITKTQTSIQNLKTNSSYRFRAYAVNEVDISDASETTEYYKVI 1474 V Y + + + +++ Q + L+ + Y F+ AVN+ + E + ++ Sbjct: 462 VYYVRVGSVRERRVDTLQVSELQLVVGELRPETGYSFQVVAVNQ---AGPGERSAPLRIT 518 Query: 1475 KETKIQSP 1482 + ++Q P Sbjct: 519 TQPEVQVP 526 Score = 61.3 bits (142), Expect = 3e-07 Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 18/177 (10%) Query: 648 GSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYCSVLKITNVKKFQEGT 707 G LEC + P P + W +G E V E SV +L+I NV++ G Sbjct: 256 GHTATLECVVAGFPAPSVHWT-RGTESVLSERFSVVAGG-------ILRIDNVQQDDAGD 307 Query: 708 YTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESVILSAQVVGNPRPTIT 767 YT + + + E L K EPP+++ ++ + +IL Q G PRP I+ Sbjct: 308 YTCI-IKAQNETQR---LYAKLTVLEPPRILHGPENRNASVSDDIILECQAEGRPRPVIS 363 Query: 768 WCKNNKPV--KALPTKSDGDTHSITILKPKKVKDEGVYTLKAENSEGIAETSAVITV 822 W +N + DG H + ++ DEGVY AE+ + +A + V Sbjct: 364 WFQNGDLIIPDDFIQIVDGSLHILGVM----ASDEGVYQCMAESEVDGMQAAAQLVV 416 Score = 57.6 bits (133), Expect = 4e-06 Identities = 67/293 (22%), Positives = 119/293 (40%), Gaps = 23/293 (7%) Query: 634 PTFSKKPKAQYVDEGSDILLECRL-VAIPEPDIAWLFKGEEIVPDENISVAIESDMHMYC 692 P F + V +G ++L+C V ++ W +G I D + V D+ + Sbjct: 144 PRFVSSSLSTLVIQGDSVVLDCGAEVTGLWNEVRWFKEGRSITEDSQVMVLSSGDLLLQ- 202 Query: 693 SVLKITNVKKFQEGTYTVVAVNREGEASLPIVLKIKTGEKEPPQVIEPLKSMIVRQGESV 752 + K K F + + +G +L ++ ++++ P V+ + VR G + Sbjct: 203 NASKADGGKYFCQLVFGGRTFTNQG-TNLSVLPEMESNR--PCVVLRHPVDVSVRLGHTA 259 Query: 753 ILSAQVVGNPRPTITWCKNNKPVKALPTKSDGDTHSITILKPKKVKDEGVYT--LKAENS 810 L V G P P++ W + + V L + I + + D G YT +KA+N Sbjct: 260 TLECVVAGFPAPSVHWTRGTESV--LSERFSVVAGGILRIDNVQQDDAGDYTCIIKAQNE 317 Query: 811 EGIAETSAVITVEEPTEENAEPPLFINRFQEITVKEKGTIKLVARVTRNPVPSITWYRNN 870 A +TV EPP ++ + I L + P P I+W++N Sbjct: 318 T--QRLYAKLTV-------LEPPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNG 368 Query: 871 EIISPSETITQNFDGENIELVITNVDSEIDSGDYKCVASNSAGKSSHGARVTI 923 ++I P + I Q DG L I V + D G Y+C+A + A++ + Sbjct: 369 DLIIPDDFI-QIVDG---SLHILGVMAS-DEGVYQCMAESEVDGMQAAAQLVV 416 Score = 46.0 bits (104), Expect = 0.011 Identities = 75/303 (24%), Positives = 124/303 (40%), Gaps = 36/303 (11%) Query: 897 SEIDSGDYKC-VASNSAGKS-SHGARVTIDVEKVTFVKHLQKSYETEEGKTVILECQTSH 954 + IDSG Y+C V + G S A VT+ + + FV S +G +V+L+C Sbjct: 112 ARIDSGRYQCEVTVHGLGSIISRPAAVTL-IGEPRFVSS-SLSTLVIQGDSVVLDCGAEV 169 Query: 955 TV---STKWYHNKKEISGMDHREIIQEGRXXXXXXXXXXXXDVGVIKC-IVKDQETSTML 1010 T +W+ + I+ ++ G D G C +V T T Sbjct: 170 TGLWNEVRWFKEGRSITEDSQVMVLSSG---DLLLQNASKADGGKYFCQLVFGGRTFTNQ 226 Query: 1011 VVK-ETIPEF--------IRKLQDFEVKEKDVAILEVEINSETADVV-WERDGEIIKPKK 1060 +PE +R D V+ A LE + A V W R E + ++ Sbjct: 227 GTNLSVLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSER 286 Query: 1061 NKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDESCT----AEVTVVELPPEIITRLQNQ 1116 + G +R I N D G+Y+CI++ ++ T A++TV+E PP I+ +N+ Sbjct: 287 --FSVVAGGILR---IDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLE-PPRILHGPENR 340 Query: 1117 KVNKGNKATFEIELT-KGDALVRWFKDGSEIQFSNHIQLTIDGKKQKLKIYDCDLDDAGE 1175 + + E + + ++ WF++G I + IQ+ +DG L I D G Sbjct: 341 NASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQI-VDG---SLHILGVMASDEGV 396 Query: 1176 YSC 1178 Y C Sbjct: 397 YQC 399 Score = 44.8 bits (101), Expect = 0.026 Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 530 ECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTCVAKNAA 589 ECQ EG PRP I+WF+ +I P DF D +L I V D G + C+A++ Sbjct: 351 ECQAEGRPRPVISWFQNGDLIIP-DDFIQIVD----GSLHILGVMASDEGVYQCMAESEV 405 Query: 590 GFASSTTELIV 600 + +L+V Sbjct: 406 DGMQAAAQLVV 416 Score = 42.7 bits (96), Expect = 0.11 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 633 PPTFSKKPKAQYVDEGSDILLECRLVAIPEPDIAWLFKGEEIVPDENISVAIESDMHM 690 PP P+ + DI+LEC+ P P I+W G+ I+PD+ I + ++ +H+ Sbjct: 330 PPRILHGPENRNASVSDDIILECQAEGRPRPVISWFQNGDLIIPDDFIQI-VDGSLHI 386 Score = 39.5 bits (88), Expect = 0.99 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 6/88 (6%) Query: 524 GSTVQFECQVEGYPRPQITWFRQTAIIKPSQDFQMYYDDDNVATLVIREVFPEDAGTFTC 583 G T EC V G+P P + W R T + S+ F + L I V +DAG +TC Sbjct: 256 GHTATLECVVAGFPAPSVHWTRGTESVL-SERFSVVAG----GILRIDNVQQDDAGDYTC 310 Query: 584 VAKNAAGFASSTTEL-IVEAPLSDHGSE 610 + K +L ++E P HG E Sbjct: 311 IIKAQNETQRLYAKLTVLEPPRILHGPE 338 Score = 36.7 bits (81), Expect = 7.0 Identities = 49/240 (20%), Positives = 87/240 (36%), Gaps = 20/240 (8%) Query: 864 ITWYRNNEIISPSETITQNFDGENIELVITNVDSEIDSGDYKC-VASNSAGKSSHGARVT 922 + W++ I+ + G+ L++ N S+ D G Y C + ++ G ++ Sbjct: 176 VRWFKEGRSITEDSQVMVLSSGD---LLLQNA-SKADGGKYFCQLVFGGRTFTNQGTNLS 231 Query: 923 I----DVEKVTFVKHLQKSYETEEGKTVILECQTSHTVSTKWYHNKKEISGMDHREIIQE 978 + + + V G T LEC + + + + S + R + Sbjct: 232 VLPEMESNRPCVVLRHPVDVSVRLGHTATLECVVAGFPAPSVHWTRGTESVLSERFSVVA 291 Query: 979 GRXXXXXXXXXXXXDVGVIKCIVKDQETSTMLVVKETI---PEFIRKLQDFEVKEKDVAI 1035 G D G CI+K Q + L K T+ P + ++ D I Sbjct: 292 G--GILRIDNVQQDDAGDYTCIIKAQNETQRLYAKLTVLEPPRILHGPENRNASVSDDII 349 Query: 1036 LEVEINSETADVV-WERDGEIIKPKKNKYDFEKRGHIRKLYIRNTSVHDEGEYSCILRDE 1094 LE + V+ W ++G++I P DF + L+I DEG Y C+ E Sbjct: 350 LECQAEGRPRPVISWFQNGDLIIPD----DFIQIVD-GSLHILGVMASDEGVYQCMAESE 404 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.312 0.131 0.377 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 2,321,944,652 Number of Sequences: 1657284 Number of extensions: 99355269 Number of successful extensions: 284776 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 690 Number of HSP's successfully gapped in prelim test: 1169 Number of HSP's that attempted gapping in prelim test: 237496 Number of HSP's gapped (non-prelim): 27038 length of query: 2130 length of database: 575,637,011 effective HSP length: 112 effective length of query: 2018 effective length of database: 390,021,203 effective search space: 787062787654 effective search space used: 787062787654 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 42 (21.8 bits) S2: 80 (36.3 bits)
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